GeneModel BLAST Result against human

BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000208-TA|BGIBMGA000208-PA|IPR013091|EGF
calcium-binding, IPR002212|Matrix fibril-associated,
IPR000152|Aspartic acid and asparagine hydroxylation site,
IPR013032|EGF-like region, IPR000742|EGF-like, type 3,
IPR001881|EGF-like calcium-binding, IPR006210|EGF
         (229 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.             197   2e-50
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.             197   2e-50
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.         197   2e-50
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.           195   9e-50
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital...   195   9e-50
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ...   193   4e-49
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ...   193   4e-49
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ...   193   4e-49
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.         193   4e-49
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.         193   4e-49
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.         193   4e-49
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.         193   4e-49
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.          193   5e-49
X62009-1|CAB56757.1|  754|Homo sapiens fibrillin 5 protein.           168   2e-41
X62008-1|CAB56534.1|  517|Homo sapiens fibrillin 15 protein.          161   2e-39
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.         161   2e-39
AK131282-1|BAD18457.1|  872|Homo sapiens protein ( Homo sapiens ...   153   7e-37
AB208840-1|BAD92077.1|  830|Homo sapiens fibrillin 1 variant pro...   147   3e-35
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p...   118   1e-26
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro...   118   2e-26
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro...   118   2e-26
BC008761-1|AAH08761.2|  743|Homo sapiens LTBP3 protein protein.       115   2e-25
AL117551-1|CAB55988.1|  511|Homo sapiens hypothetical protein pr...   115   2e-25
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.    115   2e-25
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro...   115   2e-25
M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.                 107   4e-23
BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro...   107   4e-23
AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac...   107   4e-23
AC019127-1|AAY24260.1|  697|Homo sapiens unknown protein.             107   4e-23
AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro...   107   4e-23
Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein.      105   1e-22
S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt...   105   1e-22
BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming gro...   105   1e-22
AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming gro...   105   1e-22
AF054502-1|AAC39882.1|  669|Homo sapiens latent transforming gro...    99   6e-21
AC013451-1|AAF87081.1|  969|Homo sapiens LTBP-2 protein.               97   6e-20
AC019195-1|AAY14953.1|  546|Homo sapiens unknown protein.              94   4e-19
S54426-1|AAB25244.1|  109|Homo sapiens fibrillin protein.              85   3e-16
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.           81   4e-15
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.       80   6e-15
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop...    80   6e-15
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop...    80   6e-15
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop...    80   6e-15
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.              80   6e-15
AK027344-1|BAB55049.1|  741|Homo sapiens protein ( Homo sapiens ...    80   7e-15
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq...    79   2e-14
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq...    79   2e-14
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq...    79   2e-14
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq...    79   2e-14
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq...    79   2e-14
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq...    79   2e-14
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq...    79   2e-14
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq...    79   2e-14
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.            79   2e-14
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.                 78   2e-14
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.               78   2e-14
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.              78   2e-14
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant...    78   2e-14
U76764-1|AAB36682.1|  835|Homo sapiens CD97 protein.                   78   3e-14
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai...    77   7e-14
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai...    77   7e-14
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr...    77   7e-14
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.                77   7e-14
X94630-1|CAA64333.1|  835|Homo sapiens seven-span transmembrane ...    76   9e-14
AK074499-1|BAC11024.1|  636|Homo sapiens protein ( Homo sapiens ...    76   9e-14
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.       76   9e-14
AB065966-1|BAC06178.1|  837|Homo sapiens seven transmembrane hel...    76   9e-14
X81479-1|CAA57232.1|  886|Homo sapiens EMR1 protein.                   76   1e-13
AY358898-1|AAQ89257.1|  448|Homo sapiens FBLN5 protein.                76   1e-13
DQ217942-1|ABB70739.1|  886|Homo sapiens EGF-like module contain...    75   2e-13
BC059395-1|AAH59395.1|  821|Homo sapiens EMR1 protein protein.         75   2e-13
AB065918-1|BAC06133.1|  929|Homo sapiens seven transmembrane hel...    75   2e-13
CR457140-1|CAG33421.1|  448|Homo sapiens FBLN5 protein.                75   2e-13
BC022280-1|AAH22280.1|  448|Homo sapiens fibulin 5 protein.            75   2e-13
AJ133490-1|CAB38568.1|  448|Homo sapiens fibulin-5 protein.            75   2e-13
AF112152-1|AAD41768.1|  448|Homo sapiens developmental arteries ...    75   2e-13
AK131562-1|BAD18695.1|  867|Homo sapiens protein ( Homo sapiens ...    74   4e-13
BC127005-1|AAI27006.1|  823|Homo sapiens egf-like module contain...    73   6e-13
BC127004-1|AAI27005.1|  823|Homo sapiens egf-like module contain...    73   6e-13
AC005327-1|AAC27673.1|  287|Homo sapiens CD97_HUMAN, partial CDS...    73   6e-13
AK222891-1|BAD96611.1|  810|Homo sapiens egf-like module contain...    73   1e-12
AF114491-1|AAF21974.1|  823|Homo sapiens EGF-like module EMR2 pr...    73   1e-12
AB065931-1|BAC06146.1|  837|Homo sapiens seven transmembrane hel...    73   1e-12
X53743-1|CAA37772.1|  683|Homo sapiens fibulin-1 C protein.            70   6e-12
X53742-1|CAA37771.1|  601|Homo sapiens fibulin-1 B protein.            70   6e-12
X53741-1|CAA37770.1|  566|Homo sapiens fibulin-1 A protein.            70   6e-12
U01244-1|AAB17099.1|  703|Homo sapiens fibulin-1D protein.             70   6e-12
BC022497-1|AAH22497.1|  683|Homo sapiens fibulin 1 protein.            70   6e-12
AF126110-1|AAK37822.1|  703|Homo sapiens fibulin-1 isoform D pre...    70   6e-12
Z98047-1|CAI19628.1|  703|Homo sapiens fibulin 1 protein.              70   8e-12
Z95331-3|CAI41717.1|  703|Homo sapiens fibulin 1 protein.              70   8e-12
AL021391-3|CAI18930.1|  703|Homo sapiens fibulin 1 protein.            70   8e-12
AK075566-1|BAC11705.1|  638|Homo sapiens protein ( Homo sapiens ...    70   8e-12
AF217999-1|AAG17241.1|  495|Homo sapiens unknown protein.              70   8e-12
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl...    68   2e-11
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl...    68   2e-11
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va...    68   2e-11
AL133553-4|CAI17860.1|  240|Homo sapiens protein ( Human DNA seq...    68   3e-11
Z99756-1|CAI18854.1|  988|Homo sapiens protein ( Human DNA seque...    67   4e-11
Z97832-1|CAI20187.1|  993|Homo sapiens protein ( Human DNA seque...    67   4e-11
Z82214-3|CAI21674.1|  988|Homo sapiens protein ( Human DNA seque...    67   4e-11
AY639608-1|AAU08347.1|  993|Homo sapiens signal peptide, CUB and...    67   4e-11
AF452494-1|AAN76808.1|  993|Homo sapiens CUB and EGF containing ...    67   4e-11
X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein.              66   7e-11
BC052263-1|AAH52263.2|  992|Homo sapiens signal peptide, CUB dom...    66   7e-11
BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein.            66   7e-11
AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein.            66   7e-11
AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein.            66   7e-11
AF054501-1|AAC39881.1|  161|Homo sapiens latent transforming gro...    66   1e-10
AK092062-1|BAC03798.1|  880|Homo sapiens protein ( Homo sapiens ...    65   2e-10
U03877-1|AAA65590.1|  387|Homo sapiens extracellular protein pro...    64   3e-10
CR541934-1|CAG46732.1|  443|Homo sapiens EFEMP2 protein.               64   3e-10
BC098561-1|AAH98561.1|  493|Homo sapiens EGF-containing fibulin-...    64   3e-10
BC053933-1|AAH53933.1|  239|Homo sapiens EMR2 protein protein.         64   3e-10
BC034949-1|AAH34949.1|  239|Homo sapiens EMR2 protein protein.         64   3e-10
BC014410-1|AAH14410.1|  493|Homo sapiens EGF-containing fibulin-...    64   3e-10
BC010456-1|AAH10456.1|  443|Homo sapiens EGF-containing fibulin-...    64   3e-10
AY358899-1|AAQ89258.1|  443|Homo sapiens EFEMP2 protein.               64   3e-10
AY004330-1|AAK11491.1|  493|Homo sapiens EGF-containing fibulin-...    64   3e-10
AJ132819-1|CAA10791.2|  443|Homo sapiens fibulin-4 protein.            64   3e-10
AF525689-1|AAN77133.1|  988|Homo sapiens signal peptide-CUB-EGF-...    64   3e-10
AF109121-1|AAF65188.1|  443|Homo sapiens EGF-containing fibulin-...    64   3e-10
AB209212-1|BAD92449.1|  418|Homo sapiens EGF-containing fibulin-...    64   3e-10
AB209121-1|BAD92358.1|  620|Homo sapiens Mutant p53 binding prot...    64   3e-10
AB030655-1|BAA92880.1|  443|Homo sapiens mutant p53 binding prot...    64   3e-10
AJ295142-1|CAC82720.1|  652|Homo sapiens C1q receptor protein pr...    64   4e-10
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.                   64   5e-10
L13720-1|AAA58494.1|  678|Homo sapiens growth-arrest-specific pr...    64   5e-10
BX072579-3|CAH71174.1|  678|Homo sapiens growth arrest-specific ...    64   5e-10
BC038984-1|AAH38984.1|  678|Homo sapiens growth arrest-specific ...    64   5e-10
AY256843-1|AAO84057.1|  678|Homo sapiens growth arrested-specifi...    64   5e-10
AK126533-1|BAC86580.1|  624|Homo sapiens protein ( Homo sapiens ...    64   5e-10
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.              64   5e-10
U94333-1|AAB53110.1|  652|Homo sapiens C1qR(p) protein.                63   7e-10
BC028075-1|AAH28075.1|  652|Homo sapiens CD93 molecule protein.        63   7e-10
AL118508-1|CAC00597.1|  652|Homo sapiens complement component 1,...    63   7e-10
AK131552-1|BAD18686.1|  682|Homo sapiens protein ( Homo sapiens ...    63   7e-10
AB209895-1|BAD93132.1|  671|Homo sapiens complement component 1,...    63   7e-10
BC111690-1|AAI11691.1|  807|Homo sapiens SCUBE2 protein protein.       62   1e-09
AK123039-1|BAC85521.1|  971|Homo sapiens protein ( Homo sapiens ...    62   1e-09
AJ400877-1|CAB92285.1|  999|Homo sapiens CEGP1 protein protein.        62   1e-09
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.                 61   4e-09
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.                 61   4e-09
M16552-1|AAB59508.1|  575|Homo sapiens THBD protein.                   61   4e-09
J02973-1|AAA61175.1|  575|Homo sapiens THBD protein.                   61   4e-09
D86566-1|BAA13116.1|  955|Homo sapiens notch related protein pro...    61   4e-09
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop...    61   4e-09
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop...    61   4e-09
BC063815-1|AAH63815.1|  647|Homo sapiens NOTCH4 protein protein.       61   4e-09
BC053357-1|AAH53357.1|  575|Homo sapiens thrombomodulin protein.       61   4e-09
BC038587-1|AAH38587.1|  553|Homo sapiens EGF-like-domain, multip...    61   4e-09
AY358333-1|AAQ88699.1|  338|Homo sapiens EGFL6 protein.                61   4e-09
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop...    61   4e-09
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso...    61   4e-09
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso...    61   4e-09
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop...    61   4e-09
AL049651-2|CAB51954.1|  575|Homo sapiens thrombomodulin protein.       61   4e-09
AK075214-1|BAC11477.1|  553|Homo sapiens protein ( Homo sapiens ...    61   4e-09
AJ245671-1|CAB92132.1|  554|Homo sapiens hypothetical protein pr...    61   4e-09
AF495471-1|AAM03232.1|  575|Homo sapiens thrombomodulin protein.       61   4e-09
AF186084-1|AAF27812.1|  553|Homo sapiens epidermal growth factor...    61   4e-09
AF093118-1|AAC62107.1|  448|Homo sapiens UP50 protein.                 61   4e-09
U69263-1|AAC51260.2|  956|Homo sapiens matrilin-2 precursor prot...    60   5e-09
BC016394-1|AAH16394.1|  715|Homo sapiens MATN2 protein protein.        60   5e-09
BC010444-1|AAH10444.1|  937|Homo sapiens matrilin 2 protein.           60   5e-09
AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein pr...    60   5e-09
AK075489-1|BAC11648.1|  451|Homo sapiens rase 7.  protein.             60   5e-09
AF093119-1|AAC62108.1|  439|Homo sapiens UPH1 protein.                 60   5e-09
AY358336-1|AAQ88702.1|  509|Homo sapiens DFLL295 protein.              60   6e-09
AF193055-1|AAG22483.1|  474|Homo sapiens unknown protein.              60   6e-09
AF124486-1|AAG45245.1|  443|Homo sapiens fibulin-like extracellu...    60   6e-09
X05495-1|CAA29045.1|  575|Homo sapiens thrombomodulin protein.         59   1e-08
D00210-1|BAA00149.1|  575|Homo sapiens thrombomodulin precursor ...    59   1e-08
BC035602-1|AAH35602.2|  575|Homo sapiens thrombomodulin protein.       59   1e-08
AC010895-1|AAY14669.1|  320|Homo sapiens unknown protein.              59   1e-08
AY358895-1|AAQ89254.1|  915|Homo sapiens MATN2 protein.                58   2e-08
AB023961-1|BAB20317.1|  502|Homo sapiens notch4 protein.               58   2e-08
Y00692-1|CAA68687.1|  676|Homo sapiens preproprotein S protein.        58   3e-08
M57853-1|AAA60357.1|  676|Homo sapiens S protein protein.              58   3e-08
M36564-1|AAA60180.1|  650|Homo sapiens PROS1 protein.                  58   3e-08
M15036-1|AAA36479.1|  676|Homo sapiens protein ( Human vitamin K...    58   3e-08
BC015801-1|AAH15801.1|  676|Homo sapiens PROS1 protein protein.        58   3e-08
AY308744-1|AAP45054.1|  497|Homo sapiens protein S (alpha) protein.    58   3e-08
AF011407-1|AAB64201.1|  180|Homo sapiens latent TGF beta binding...    58   3e-08
BC127263-1|AAI27264.1|  363|Homo sapiens SCUBE1 protein protein.       57   6e-08
AK027775-1|BAB55358.1|  537|Homo sapiens protein ( Homo sapiens ...    57   6e-08
X84700-1|CAA59173.1|  742|Homo sapiens leucocyte antigen CD97 pr...    56   1e-07
BC026690-1|AAH26690.1|  742|Homo sapiens CD97 molecule protein.        56   1e-07
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ...    56   1e-07
AK074396-1|BAB85069.1|  220|Homo sapiens protein ( Homo sapiens ...    55   2e-07
BC077719-1|AAH77719.1|  219|Homo sapiens VWCE protein protein.         55   2e-07
BC052564-1|AAH52564.1|  219|Homo sapiens VWCE protein protein.         55   2e-07
BC042143-1|AAH42143.1|  237|Homo sapiens VWCE protein protein.         55   2e-07
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs...    55   2e-07
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso...    55   2e-07
AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso...    55   2e-07
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso...    55   2e-07
AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso...    55   2e-07
AK056571-1|BAB71219.1|  955|Homo sapiens protein ( Homo sapiens ...    55   2e-07
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.                 55   2e-07
AB208923-1|BAD92160.1|  441|Homo sapiens crumbs homolog 1 isofor...    55   2e-07
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.     54   3e-07
X12892-1|CAA31383.1|  650|Homo sapiens protein ( H.sapiens mRNA ...    54   4e-07
M17778-1|AAA36799.1|  640|Homo sapiens protein ( Human uromoduli...    54   4e-07
M15881-1|AAA36798.1|  640|Homo sapiens protein ( Human uromoduli...    54   4e-07
M14338-1|AAA60181.1|  650|Homo sapiens protein S precursor protein.    54   4e-07
BC035975-1|AAH35975.1|  611|Homo sapiens UMOD protein protein.         54   4e-07
AY162970-1|AAO64446.1|  640|Homo sapiens uromodulin precursor pr...    54   4e-07
D83017-1|BAA11680.1|  810|Homo sapiens nel-related protein protein.    53   7e-07
BC096102-1|AAH96102.1|  810|Homo sapiens NEL-like 1 (chicken) pr...    53   7e-07
BC096101-1|AAH96101.1|  810|Homo sapiens NEL-like 1 (chicken) pr...    53   7e-07
BC069674-1|AAH69674.1|  810|Homo sapiens nel-like 1, precursor p...    53   7e-07
X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for ...    52   1e-06
BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor...    52   1e-06
BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor...    52   1e-06
AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal gro...    52   1e-06
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag...    52   2e-06
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.               52   2e-06
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag...    52   2e-06
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd...    52   2e-06
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd...    52   2e-06
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd...    52   2e-06
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd...    52   2e-06
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J...    52   2e-06
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.              52   2e-06
BC035784-1|AAH35784.1|  439|Homo sapiens hypothetical protein FL...    50   5e-06
AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso...    50   5e-06
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso...    50   5e-06
AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso...    50   5e-06
AK094759-1|BAC04416.1|  439|Homo sapiens protein ( Homo sapiens ...    50   5e-06
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt...    50   5e-06
AC092645-2|AAY14854.1|  439|Homo sapiens unknown protein.              50   5e-06
U57523-1|AAB06946.1|  446|Homo sapiens protein ( Human nel homol...    50   7e-06
BC106950-1|AAI06951.1|  685|Homo sapiens delta-like 4 (Drosophil...    50   7e-06
AY358894-1|AAQ89253.1|  685|Homo sapiens DLL4 protein.                 50   7e-06
AF279305-1|AAF81912.1|  653|Homo sapiens delta 4 protein.              50   7e-06
AF253468-1|AAF76427.1|  685|Homo sapiens notch ligand DLL4 protein.    50   7e-06
AB043894-1|BAB18581.1|  685|Homo sapiens Delta-4 protein.              50   7e-06
AB036931-1|BAB16085.1|  685|Homo sapiens notch ligand delta-2 pr...    50   7e-06
D89629-1|BAB46925.1|  815|Homo sapiens cerebral protein-12 protein.    50   9e-06
D83018-1|BAA11681.1|  816|Homo sapiens nel-related protein 2 pro...    50   9e-06
BC020544-1|AAH20544.1|  816|Homo sapiens NELL2 protein protein.        50   9e-06
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.         50   9e-06
D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein.           49   1e-05
BC113577-1|AAI13578.1| 1015|Homo sapiens tolloid-like 2 protein.       49   1e-05
BC112366-1|AAI12367.1| 1015|Homo sapiens tolloid-like 2 protein.       49   1e-05
BC112341-1|AAI12342.1| 1015|Homo sapiens tolloid-like 2 protein.       49   1e-05
BC035608-1|AAH35608.1|  969|Homo sapiens NID2 protein protein.         49   1e-05
AL391136-1|CAH72234.1| 1015|Homo sapiens tolloid-like 2 protein.       49   1e-05
AL138765-2|CAI13580.1| 1015|Homo sapiens tolloid-like 2 protein.       49   1e-05
AL136181-1|CAH72983.1| 1015|Homo sapiens tolloid-like 2 protein.       49   1e-05
AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein.            49   1e-05
AF059516-1|AAD42979.1| 1015|Homo sapiens tolloid-like 2 protein ...    49   1e-05
AB023149-1|BAA76776.2| 1078|Homo sapiens KIAA0932 protein protein.     49   1e-05
AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein.         49   1e-05
AY358892-1|AAQ89251.1|  723|Homo sapiens DLL1 protein.                 49   2e-05
AL078605-2|CAB89569.1|  723|Homo sapiens delta-like 1 (Drosophil...    49   2e-05
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami...    49   2e-05
AF222310-1|AAG09716.1|  723|Homo sapiens Delta1 protein.               49   2e-05
AF196571-1|AAF05834.1|  723|Homo sapiens Delta-like-1 protein pr...    49   2e-05
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re...    49   2e-05
AF003522-1|AAB61286.1|  723|Homo sapiens Delta protein.                49   2e-05
X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein.                48   2e-05
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein.        48   2e-05
U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein.       48   2e-05
M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein.                48   2e-05
M27445-1|AAA57261.1|  581|Homo sapiens nidogen protein.                48   2e-05
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g...    48   2e-05
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g...    48   2e-05
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p...    48   2e-05
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact...    48   2e-05
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact...    48   2e-05
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact...    48   2e-05
AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein.            48   2e-05
AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein.            48   2e-05
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.       48   2e-05
AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein.              48   2e-05
BC096103-1|AAH96103.1|  763|Homo sapiens NELL1 protein protein.        48   3e-05
BC096100-1|AAH96100.1|  763|Homo sapiens NELL1 protein protein.        48   3e-05
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p...    48   3e-05
AY165866-1|AAO18148.1|   41|Homo sapiens fibrillin-3 precursor p...    48   3e-05
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso...    48   3e-05
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso...    48   3e-05
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso...    48   3e-05
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso...    48   3e-05
AK123000-1|BAC85516.1| 1176|Homo sapiens  3 (HIVEP3).  protein.        48   3e-05
BC126986-1|AAI26987.1|  393|Homo sapiens FLJ37440 protein protein.     48   4e-05
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres...    48   4e-05
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein...    48   4e-05
AC093039-1|AAX88911.1|  425|Homo sapiens unknown protein.              48   4e-05
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein...    48   4e-05
AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) varia...    48   4e-05
Y08724-1|CAA69974.1|  622|Homo sapiens BMP1-5 protein.                 47   5e-05
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f...    47   5e-05
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f...    47   5e-05
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f...    47   5e-05
Y08725-1|CAA69975.1|  717|Homo sapiens BMP1-6 protein.                 47   6e-05
U50330-1|AAA93462.1|  986|Homo sapiens procollagen C-proteinase ...    47   6e-05
M22488-1|AAA51833.1|  730|Homo sapiens BMP1 protein.                   47   6e-05
AB209590-1|BAD92827.1|  803|Homo sapiens bone morphogenetic prot...    47   6e-05
AB024578-1|BAA88952.1|   78|Homo sapiens notch4 protein.               47   6e-05
AL021578-2|CAI21077.1|  432|Homo sapiens matrilin 4 protein.           46   8e-05
U91963-1|AAB93878.1| 1013|Homo sapiens tolloid-like protein prot...    46   1e-04
BC105633-1|AAI05634.1|  757|Homo sapiens tumor endothelial marke...    46   1e-04
BC104484-1|AAI04485.1|  757|Homo sapiens tumor endothelial marke...    46   1e-04
BC088371-1|AAH88371.1|  273|Homo sapiens EGF-like-domain, multip...    46   1e-04
BC051340-1|AAH51340.1|  757|Homo sapiens CD248 molecule, endosia...    46   1e-04
BC012377-1|AAH12377.1|  273|Homo sapiens EGF-like-domain, multip...    46   1e-04
AY358902-1|AAQ89261.1|  273|Homo sapiens VEMF protein.                 46   1e-04
AY358901-1|AAQ89260.1|  273|Homo sapiens VEMF protein.                 46   1e-04
AJ295846-1|CAC34381.1|  757|Homo sapiens endosialin protein prot...    46   1e-04
AF282732-1|AAF86287.1| 1013|Homo sapiens tolloid-like protein pr...    46   1e-04
AF279142-1|AAG00867.1|  757|Homo sapiens tumor endothelial marke...    46   1e-04
AF135961-1|AAF62353.2|   46|Homo sapiens latent transforming gro...    46   1e-04
AB125649-1|BAD01469.1|  273|Homo sapiens VE-statin protein.            46   1e-04
L00352-1|AAA56833.1|  860|Homo sapiens low density lipoprotein r...    46   1e-04
BT007361-1|AAP36025.1|  860|Homo sapiens low density lipoprotein...    46   1e-04
BC038242-1|AAH38242.1|  261|Homo sapiens Similar to RIKEN cDNA 1...    46   1e-04
BC014514-1|AAH14514.1|  860|Homo sapiens low density lipoprotein...    46   1e-04
AY358903-1|AAQ89262.1|  273|Homo sapiens VEMF protein.                 46   1e-04
AY324609-1|AAP72971.1|  860|Homo sapiens low density lipoprotein...    46   1e-04
AY114155-1|AAM56036.1|  860|Homo sapiens low density lipoprotein...    46   1e-04
AL590226-1|CAH71721.1|  273|Homo sapiens EGF-like-domain, multip...    46   1e-04
AF217403-1|AAF24515.1|  837|Homo sapiens low density lipoprotein...    46   1e-04
AF186111-1|AAF01429.1|  273|Homo sapiens NOTCH4-like protein pro...    46   1e-04
AB231861-1|BAE19679.1| 1950|Homo sapiens low-density lipoprotein...    46   1e-04
AB209409-1|BAD92646.1|  870|Homo sapiens low density lipoprotein...    46   1e-04
AB084910-1|BAD83615.1| 1905|Homo sapiens low density lipoprotein...    46   1e-04
AB083391-1|BAC54139.1|   41|Homo sapiens Protein S protein.            46   1e-04
D86407-2|BAA21825.1|  793|Homo sapiens ApoER2delta4-7 protein.         45   2e-04
D86407-1|BAA21824.1|  963|Homo sapiens ApoER2 protein.                 45   2e-04
D50678-1|BAA09328.1|  963|Homo sapiens apolipoprotein E receptor...    45   2e-04
BC051836-1|AAH51836.2|  904|Homo sapiens low density lipoprotein...    45   2e-04
AL606760-4|CAI18908.1|  963|Homo sapiens low density lipoprotein...    45   2e-04
AL606760-3|CAI18909.1|  700|Homo sapiens low density lipoprotein...    45   2e-04
AL606760-2|CAI18910.1|  904|Homo sapiens low density lipoprotein...    45   2e-04
AL355483-3|CAI22782.1|  700|Homo sapiens low density lipoprotein...    45   2e-04
AL355483-2|CAI22780.1|  904|Homo sapiens low density lipoprotein...    45   2e-04
AL355483-1|CAI22781.1|  963|Homo sapiens low density lipoprotein...    45   2e-04
BC060770-1|AAH60770.2|  757|Homo sapiens SUSD1 protein protein.        45   3e-04
BC027939-1|AAH27939.1|  600|Homo sapiens SNED1 protein protein.        45   3e-04
AY358746-1|AAQ89106.1|  747|Homo sapiens GRGP2438 protein.             45   3e-04
AL158824-3|CAI12348.2|  705|Homo sapiens sushi domain containing...    45   3e-04
AL158824-2|CAI12347.2|  747|Homo sapiens sushi domain containing...    45   3e-04
AL138756-2|CAI95300.2|  705|Homo sapiens sushi domain containing...    45   3e-04
AL138756-1|CAI95299.2|  747|Homo sapiens sushi domain containing...    45   3e-04
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ...    45   3e-04
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.              45   3e-04
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.              45   3e-04
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.             45   3e-04
AC020594-1|AAY15036.1|  150|Homo sapiens unknown protein.              45   3e-04
U89336-6|AAB47494.1|  293|Homo sapiens NG3 protein.                    44   3e-04
S73849-1|AAB31735.1|  873|Homo sapiens very low density lipoprot...    44   3e-04
L22431-1|AAA61344.1|  873|Homo sapiens very low density lipoprot...    44   3e-04
D16532-1|BAA03969.1|  873|Homo sapiens very low density lipoprot...    44   3e-04
D16494-1|BAA03946.1|  845|Homo sapiens very low density lipoprot...    44   3e-04
D16493-1|BAA03945.1|  873|Homo sapiens very low density lipoprot...    44   3e-04
DQ067198-1|AAY46157.1|  873|Homo sapiens very low density lipopr...    44   3e-04
BX284686-12|CAM26220.1|  293|Homo sapiens EGF-like-domain, multi...    44   3e-04
BC090943-1|AAH90943.1|  249|Homo sapiens NOTCH2NL protein protein.     44   3e-04
BC065219-1|AAH65219.2|  236|Homo sapiens Notch homolog 2 (Drosop...    44   3e-04
BC052591-1|AAH52591.1|  293|Homo sapiens EGF-like-domain, multip...    44   3e-04
BC035574-1|AAH35574.1|  293|Homo sapiens EGF-like-domain, multip...    44   3e-04
BC019835-1|AAH19835.1|  236|Homo sapiens Notch homolog 2 N-termi...    44   3e-04
AY358139-1|AAQ88506.1|  293|Homo sapiens NG3 protein.                  44   3e-04
AL845464-11|CAI41800.2|  293|Homo sapiens EGF-like-domain, multi...    44   3e-04
AL662884-17|CAI18345.2|  293|Homo sapiens EGF-like-domain, multi...    44   3e-04
AL662828-17|CAI17428.1|  293|Homo sapiens EGF-like-domain, multi...    44   3e-04
AL450467-4|CAH72455.1|  845|Homo sapiens very low density lipopr...    44   3e-04
AL450467-3|CAH72454.1|  873|Homo sapiens very low density lipopr...    44   3e-04
AL450467-2|CAH72453.1|  752|Homo sapiens very low density lipopr...    44   3e-04
AK092381-1|BAC03874.1|  752|Homo sapiens protein ( Homo sapiens ...    44   3e-04
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.             44   3e-04
AB208822-1|BAD92059.1|  555|Homo sapiens Very low-density lipopr...    44   3e-04
AB190520-1|BAD51398.1|  293|Homo sapiens VE-statin2 protein.           44   3e-04
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.        44   4e-04
AY358360-1|AAQ88726.1|  690|Homo sapiens ETL protein.                  44   4e-04
AY358347-1|AAQ88713.1|  406|Homo sapiens VPPP1921 protein.             44   4e-04
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ...    44   4e-04
AL596269-1|CAI13205.1|  690|Homo sapiens EGF, latrophilin and se...    44   4e-04
AL021578-1|CAB46380.1|  622|Homo sapiens matrilin 4 protein.           44   4e-04
AB075863-1|BAB85569.1|  418|Homo sapiens KIAA1983 protein protein.     44   4e-04
AB032017-1|BAD83584.1|  690|Homo sapiens KPG_003 protein protein.      44   4e-04
AB011540-1|BAA32468.1| 1576|Homo sapiens MEGF7 protein.                44   4e-04
U77493-1|AAB19224.1|  263|Homo sapiens Notch2 protein.                 44   6e-04
D86864-1|BAA24070.1|  830|Homo sapiens acetyl LDL receptor protein.    44   6e-04
D63483-1|BAA09770.1|  830|Homo sapiens KIAA0149 protein.               44   6e-04
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph...    44   6e-04
BC039735-1|AAH39735.1|  830|Homo sapiens scavenger receptor clas...    44   6e-04
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.                44   6e-04
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula...    44   6e-04
AB052948-1|BAC02694.1|  569|Homo sapiens SREC-3 protein.               44   6e-04
AB052946-1|BAC02692.1|  830|Homo sapiens SREC protein.                 44   6e-04
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.       44   6e-04
Y00406-1|CAA68467.1|  933|Homo sapiens protein ( Human mRNA for ...    43   8e-04
X17358-1|CAA35235.1|  876|Homo sapiens protein ( Human mRNA from...    43   8e-04
M55702-2|AAA61218.1|  264|Homo sapiens thyroperoxidase protein.        43   8e-04
M55702-1|AAA61219.1|  260|Homo sapiens thyroperoxidase protein.        43   8e-04
M25715-1|AAA97517.1|  933|Homo sapiens TPO protein.                    43   8e-04
M17755-1|AAA61217.2|  933|Homo sapiens thyroid peroxidase protein.     43   8e-04
J02970-1|AAA61216.1|  876|Homo sapiens TPO protein.                    43   8e-04
J02969-1|AAA61215.1|  933|Homo sapiens TPO protein.                    43   8e-04
DQ011222-1|AAY16985.1|  933|Homo sapiens thyroid peroxidase prot...    43   8e-04
BX537434-1|CAD97676.1|  236|Homo sapiens hypothetical protein pr...    43   8e-04
BC095448-1|AAH95448.1|  933|Homo sapiens thyroid peroxidase prot...    43   8e-04
BC084572-1|AAH84572.1|  343|Homo sapiens NOTCH2NL protein protein.     43   8e-04
BC010154-1|AAH10154.3|  236|Homo sapiens Notch homolog 2 (Drosop...    43   8e-04
AL592307-2|CAH73994.1|  230|Homo sapiens Notch homolog 2 (Drosop...    43   8e-04
AL592307-1|CAH73993.1|  236|Homo sapiens Notch homolog 2 (Drosop...    43   8e-04
AK075065-1|BAC11381.1|  269|Homo sapiens protein ( Homo sapiens ...    43   8e-04
AF533530-1|AAN04473.1|  350|Homo sapiens thyroid peroxidase isof...    43   8e-04
AC105450-1|AAX93261.1|  916|Homo sapiens unknown protein.              43   8e-04
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec...    43   0.001
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein...    43   0.001
AF283342-1|AAL38107.1|  881|Homo sapiens candidate tumor suppres...    43   0.001
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re...    43   0.001
AC068287-1|AAY24318.1|  223|Homo sapiens unknown protein.              43   0.001
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein...    43   0.001
BC047916-1|AAH47916.1|  347|Homo sapiens SCUBE1 protein protein.       42   0.001
L20470-1|AAA53684.1|  873|Homo sapiens very low density lipoprot...    42   0.002
BC128053-1|AAI28054.1|  409|Homo sapiens EMR3 protein protein.         42   0.002
BC121131-1|AAI21132.2|  377|Homo sapiens EMR3 protein protein.         42   0.002
BC121130-1|AAI21131.2|  409|Homo sapiens EMR3 protein protein.         42   0.002
AF239764-1|AAK15076.1|  652|Homo sapiens EGF-like module-contain...    42   0.002
AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein.     42   0.002
Z75190-1|CAA99509.1|  699|Homo sapiens apolipoprotein E receptor...    42   0.002
X14787-1|CAA32889.1| 1170|Homo sapiens precursor polypeptide (AA...    42   0.002
X04665-1|CAA28370.1| 1170|Homo sapiens protein ( Human mRNA for ...    42   0.002
L35279-1|AAC41710.1|  284|Homo sapiens bone morphogenetic protei...    42   0.002
DQ470676-1|ABF06668.1|  321|Homo sapiens CRELD2-alpha protein.         42   0.002
BC072015-1|AAH72015.1|  296|Homo sapiens LRP1 protein protein.         42   0.002
BC052593-1|AAH52593.1|  296|Homo sapiens LRP1 protein protein.         42   0.002
BC050456-1|AAH50456.1|  961|Homo sapiens thrombospondin 4 protein.     42   0.002
BC045107-1|AAH45107.1|  292|Homo sapiens LRP1 protein protein.         42   0.002
BC021204-1|AAH21204.1|  439|Homo sapiens LRP1 protein protein.         42   0.002
BC002894-1|AAH02894.1|  321|Homo sapiens CRELD2 protein protein.       42   0.002
AY566253-1|AAS66982.1|  961|Homo sapiens thrombospondin 4 protein.     42   0.002
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.                42   0.002
AF075240-1|AAD19336.1|  850|Homo sapiens SLIT1 protein protein.        42   0.002
AB209912-1|BAD93149.1| 1225|Homo sapiens thrombospondin 1 precur...    42   0.002
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.       42   0.002
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.                42   0.002
Z19585-1|CAA79635.1|  961|Homo sapiens thrombospondin-4 protein.       41   0.003
AF439430-1|AAL74416.1|  760|Homo sapiens thyroid peroxidase prot...    41   0.003
L32137-1|AAA57253.1|  757|Homo sapiens matrix protein protein.         41   0.004
DQ470680-1|ABF06672.1|  373|Homo sapiens CRELD2-zeta protein.          41   0.004
DQ470679-1|ABF06671.1|  402|Homo sapiens CRELD2-epsilon protein.       41   0.004
DQ470678-1|ABF06670.1|  353|Homo sapiens CRELD2-delta protein.         41   0.004
DQ470677-1|ABF06669.1|  325|Homo sapiens CRELD2-gamma protein.         41   0.004
AY771620-1|AAX14815.1| 1318|Homo sapiens olfactorin short isofor...    41   0.004
AY771619-1|AAX14814.1| 1446|Homo sapiens olfactorin long isoform...    41   0.004
AY358355-1|AAQ88721.1|  353|Homo sapiens RLPR185 protein.              41   0.004
AK223216-1|BAD96936.1|  757|Homo sapiens cartilage oligomeric ma...    41   0.004
AB086984-1|BAC53888.1|  757|Homo sapiens cartilage oligomeric ma...    41   0.004
AB051811-1|BAD23799.1| 1246|Homo sapiens Uromodulin-like protein...    41   0.004
AB051810-1|BAD23798.1| 1374|Homo sapiens Uromodulin-like protein...    41   0.004
BC034245-1|AAH34245.1|  451|Homo sapiens CRTAC1 protein protein.       40   0.006
BC024766-1|AAH24766.2|  454|Homo sapiens DNER protein protein.         40   0.006
AY358891-1|AAQ89250.1|  737|Homo sapiens QPRR262 protein.              40   0.006
AL358938-7|CAI14277.1|  661|Homo sapiens cartilage acidic protei...    40   0.006
AL139239-4|CAI12585.1|  661|Homo sapiens cartilage acidic protei...    40   0.006
AL139239-3|CAI12584.1|  637|Homo sapiens cartilage acidic protei...    40   0.006
AJ421515-1|CAD13394.1|  637|Homo sapiens CRTAC1-B protein protein.     40   0.006
AJ279016-1|CAC08451.1|  653|Homo sapiens chondrocyte expressed p...    40   0.006
AJ276171-3|CAB98269.1|  650|Homo sapiens ASPIC protein.                40   0.006
AJ276171-2|CAB98268.1|  653|Homo sapiens ASPIC protein.                40   0.006
AJ276171-1|CAB98267.1|  661|Homo sapiens ASPIC protein.                40   0.006
AF442487-1|AAM21557.1|  737|Homo sapiens delta-notch-like EGF re...    40   0.006
AC008273-1|AAF19247.2|  291|Homo sapiens unknown protein.              40   0.006
BC050675-1|AAH50675.1|  353|Homo sapiens cysteine-rich with EGF-...    40   0.007
U15979-1|AAA75364.1|  382|Homo sapiens dlk protein.                    40   0.010
BC125092-1|AAI25093.1|  757|Homo sapiens cartilage oligomeric ma...    40   0.010
BC110847-1|AAI10848.1|  757|Homo sapiens cartilage oligomeric ma...    40   0.010
BC035009-1|AAH35009.1|  737|Homo sapiens delta/notch-like EGF re...    40   0.010
AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein.              40   0.010
AC003107-1|AAB86501.1|  817|Homo sapiens COMP_HUMAN protein.           40   0.010
U77914-1|AAC50909.1|  263|Homo sapiens soluble protein Jagged pr...    39   0.013
AK126775-1|BAC86684.1|  952|Homo sapiens protein ( Homo sapiens ...    39   0.013
U15981-1|AAA75365.1|  310|Homo sapiens dlk protein.                    39   0.017
AL359813-8|CAI23223.1|  377|Homo sapiens EGF-like-domain, multip...    38   0.022
AK128680-1|BAC87567.1|  191|Homo sapiens protein ( Homo sapiens ...    38   0.022
AJ968414-1|CAI91316.1|  284|Homo sapiens Cysteine-rich with EGF-...    38   0.022
CR457380-1|CAG33661.1|  422|Homo sapiens CRELD1 protein.               38   0.029
BC131763-1|AAI31764.1|  581|Homo sapiens matrilin 4 protein.           38   0.029
BC008720-1|AAH08720.1|  422|Homo sapiens cysteine-rich with EGF-...    38   0.029
AY358363-1|AAQ88729.1|  420|Homo sapiens CRELD1 protein.               38   0.029
AL021578-3|CAB39280.1|  581|Homo sapiens matrilin 4 protein.           38   0.029
AJ007581-1|CAA07569.1|  581|Homo sapiens matrilin-4 protein.           38   0.029
AF452623-1|AAM75206.1|  420|Homo sapiens cysteine-rich with EGF-...    38   0.029
AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein.                 38   0.029
AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein.       38   0.039
AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo ...    38   0.039
X02750-1|CAA26528.1|  461|Homo sapiens protein ( Human liver mRN...    37   0.051
M12712-1|AAA60165.1|  462|Homo sapiens PROC protein.                   37   0.051
M11228-1|AAA60166.1|  461|Homo sapiens protein ( Human protein C...    37   0.051
BX640729-1|CAE45845.1|  674|Homo sapiens hypothetical protein pr...    37   0.051
BC034377-1|AAH34377.1|  461|Homo sapiens protein C (inactivator ...    37   0.051
AL136322-1|CAI16644.1|  674|Homo sapiens crumbs homolog 1 (Droso...    37   0.051
AF378903-1|AAK56377.1|  461|Homo sapiens protein C protein.            37   0.051
AC068282-2|AAY15044.1|  461|Homo sapiens unknown protein.              37   0.051

>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
          Length = 3002

 Score =  197 bits (481), Expect = 2e-50
 Identities = 88/208 (42%), Positives = 112/208 (53%), Gaps = 4/208 (1%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G NCTDV+EC  P +C  G C+NT GSY C CPP++EL      C D+R   CY  +  R
Sbjct: 1613 GGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPR 1672

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
                    S+E+    + A+CCCS+G AWG  C+ CP   +  Y+ LCPGG G++P   P
Sbjct: 1673 GDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRP--NP 1730

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
                V L DIDEC    GLC  G C NTFGSF C C  G+ L               P +
Sbjct: 1731 --ITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGI 1788

Query: 183  CGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
            CGPG C N  G+Y C+CP  Y+ +  G+
Sbjct: 1789 CGPGTCYNTVGNYTCICPPDYMQVNGGN 1816



 Score =  161 bits (391), Expect = 2e-39
 Identities = 82/204 (40%), Positives = 106/204 (51%), Gaps = 10/204 (4%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D+DEC+  P  C+ G C+NT+GS+ C+CP    L + G  C D R   C+    L
Sbjct: 1036 GTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCF----L 1091

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGYQPVL 120
            R   E C  +  ++    M ACCCSVGAAWG   C+ CP   +  Y +LCP GPG+    
Sbjct: 1092 RYEDEEC--TLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFA-TK 1148

Query: 121  EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXR 179
            E  +      DI+EC     LC HG C NT GSF C C +G++L +              
Sbjct: 1149 EITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRIS 1208

Query: 180  PDVCGPGVCRNLPGSYVCLCPEGY 203
            PD+CG G C N PG + C C EGY
Sbjct: 1209 PDLCGRGQCVNTPGDFECKCDEGY 1232



 Score =  148 bits (359), Expect = 1e-35
 Identities = 76/204 (37%), Positives = 104/204 (50%), Gaps = 16/204 (7%)

Query: 6    CTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC + P+ C  G C NT+GS+ C CP  + L S G  C D R + CY K      
Sbjct: 2142 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKF----- 2196

Query: 65   TETCRDSDELSEDGTMAACCCSV-GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPP 123
             E  + S   S + +   CCC++ G  WG+ C+ CP    EA+RQ+CP G G   ++ P 
Sbjct: 2197 -EGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGI--IVGPD 2253

Query: 124  SYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC 183
               V   D+DEC   + +C HG C NT GS+ C C  G++LA              P  C
Sbjct: 2254 DSAV---DMDECKEPD-VCKHGQCINTDGSYRCECPFGYTLAGNECVDTDECSVGNP--C 2307

Query: 184  GPGVCRNLPGSYVCLCPEGYVAMP 207
            G G C+N+ G + C C EG+   P
Sbjct: 2308 GNGTCKNVIGGFECTCEEGFEPGP 2331



 Score =  137 bits (331), Expect = 3e-32
 Identities = 71/209 (33%), Positives = 102/209 (48%), Gaps = 18/209 (8%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  C D++EC++P  C  G+C+NT GSY C C P   +  DG  C D+  ++ CYG    
Sbjct: 739 GRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYG---- 794

Query: 62  RSGTETCRDSDELSEDGTMAACCC-SVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
             G +  +    L    T + CCC S   A+G  C PCP   S  Y+ LC  GPG     
Sbjct: 795 --GYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAG 852

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXR 179
                    +DI+ECA    +C +G C N  G++ C C +G+ + +              
Sbjct: 853 ---------SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLN 903

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
             +C  G CRN PGS+VC CP+G++  P+
Sbjct: 904 SLLCDNGQCRNTPGSFVCTCPKGFIYKPD 932



 Score =  137 bits (331), Expect = 3e-32
 Identities = 69/209 (33%), Positives = 104/209 (49%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D +EC++ P  C+ G+C+NT+GSYTC C   +    +   C D+R+  C+ +V L
Sbjct: 2417 GEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEV-L 2475

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++    C+         T + CCC  G  WG +C+ CP  G+ A+++LCP G G      
Sbjct: 2476 QN---MCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRG------ 2526

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               ++   ADIDEC     +C +G C N  GS+ C C  G++                 P
Sbjct: 2527 ---FMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAP 2583

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GSY C CP+GY+   +G
Sbjct: 2584 KPCN-FICKNTEGSYQCSCPKGYILQEDG 2611



 Score =  136 bits (330), Expect = 5e-32
 Identities = 75/202 (37%), Positives = 98/202 (48%), Gaps = 12/202 (5%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C DV+EC++P  C  G C NT G+YTC CPP+Y  V+ G  C D R++ CY   +  +  
Sbjct: 1777 CDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYR--NYYADN 1834

Query: 66   ETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPG-GPGYQPVLEP 122
            +TC    EL  + T   CCCS  +G AW   C+ CP P ++ +  LC    PG+  V++ 
Sbjct: 1835 QTC--DGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGF--VID- 1889

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
              Y     DIDEC    G+C +G C N  GSF C C  G+                   V
Sbjct: 1890 -IYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV 1948

Query: 183  CGPGV-CRNLPGSYVCLCPEGY 203
            C     C N  GSY C C  GY
Sbjct: 1949 CQRNAECINTAGSYRCDCKPGY 1970



 Score =  105 bits (253), Expect = 1e-22
 Identities = 66/210 (31%), Positives = 91/210 (43%), Gaps = 23/210 (10%)

Query: 6    CTDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC++   CQ   +CINT GSY C C P Y   S G         +C  + + +  
Sbjct: 1937 CEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG---------QCNDRNECQEI 1987

Query: 65   TETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE--- 121
               C     +   G+   C C  G    +    C +  +E  R  C  G     +     
Sbjct: 1988 PNICSHGQCIDTVGSFY-CLCHTGFKTNDDQTMCLDI-NECERDACGNGTCRNTIGSFNC 2045

Query: 122  --PPSYVVT----LADIDECAAHEG-LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
                 ++++      D+DECA+  G LC +G C NT GSF C C  G+ +AP        
Sbjct: 2046 RCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDI 2105

Query: 175  XX-XXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  C PG C+NL GSY C+CP GY
Sbjct: 2106 NECLLEPRKCAPGTCQNLDGSYRCICPPGY 2135



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 67/214 (31%), Positives = 93/214 (43%), Gaps = 22/214 (10%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  GQC+NT G + C+C   YE      + +   K  C    + + 
Sbjct: 1198 NCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYE------SGFMMMK-NCMDIDECQR 1250

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS-EAYRQLCPGGP------GY 116
                CR     + +G+   C C  G         C +    E    LCP G        Y
Sbjct: 1251 DPLLCRGGVCHNTEGSYR-CECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKY 1309

Query: 117  QPVLEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
            Q    P  +         DIDEC+   G C    CTN+ GS+ C+C  G++L P      
Sbjct: 1310 QCACNPGYHSTPDRLFCVDIDECSIMNGGC-ETFCTNSEGSYECSCQPGFALMPDQRSCT 1368

Query: 173  XXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                    P++C  G C N+PG Y CLC +G++A
Sbjct: 1369 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMA 1402



 Score = 96.7 bits (230), Expect = 6e-20
 Identities = 72/226 (31%), Positives = 93/226 (41%), Gaps = 28/226 (12%)

Query: 2    PGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            P  +  D+DECK P  C++GQCINT GSY C CP  Y L   G  C D+ +      V  
Sbjct: 2252 PDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYTLA--GNECVDTDEC----SVGN 2305

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY--CDPCPE----PGSEAYRQLCPGGPG 115
              G  TC++     E      C C  G   G    C+   E    P   A+R  C    G
Sbjct: 2306 PCGNGTCKNVIGGFE------CTCEEGFEPGPMMTCEDINECAQNPLLCAFR--CVNTYG 2357

Query: 116  YQPVLEPPSYVV-----TLADIDECAAHEGLCAHG--TCTNTFGSFVCTCGAGWSLAPXX 168
                  P  YV+        D DEC   +  C      C N  G+++C CG G+   P  
Sbjct: 2358 SYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDG 2417

Query: 169  XX-XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
                       +P +C  G C N  GSY C C +G+ A PN  + L
Sbjct: 2418 EGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 2463



 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 69/212 (32%), Positives = 91/212 (42%), Gaps = 16/212 (7%)

Query: 6    CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCYGKVD 60
            C D +EC+  P  C +GQCI+T GS+ C C   ++   D T C D     R A   G   
Sbjct: 1978 CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCR 2037

Query: 61   LRSGTETCRDSDE--LSEDGTMAACC-CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
               G+  CR +    LS +        C+ G   GN C       +    Q C    GY+
Sbjct: 2038 NTIGSFNCRCNHGFILSHNNDCIDVDECASGN--GNLCRNGQCINTVGSFQ-CQCNEGYE 2094

Query: 118  PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
              + P     T  DI+EC      CA GTC N  GS+ C C  G+SL             
Sbjct: 2095 --VAPDGR--TCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL-QNEKCEDIDECV 2149

Query: 178  XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              P++C  G C N  GS+ CLCPEG+    +G
Sbjct: 2150 EEPEICALGTCSNTEGSFKCLCPEGFSLSSSG 2181



 Score = 87.4 bits (207), Expect = 4e-17
 Identities = 48/134 (35%), Positives = 60/134 (44%), Gaps = 12/134 (8%)

Query: 79  TMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAH 138
           T   CC +VG AWG+ C+ CP        Q  P   G+ P +   +      D+DEC A 
Sbjct: 336 TKTLCCATVGRAWGHPCEMCPA-------QPHPCRRGFIPNIRTGA----CQDVDECQAI 384

Query: 139 EGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCGPGVCRNLPGSYVC 197
            GLC  G C NT GSF C C AG  L                P +C  G C N   SY C
Sbjct: 385 PGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFC 444

Query: 198 LCPEGYVAMPNGSQ 211
            CP G+   P+G++
Sbjct: 445 KCPPGFYTSPDGTR 458



 Score = 87.4 bits (207), Expect = 4e-17
 Identities = 58/211 (27%), Positives = 83/211 (39%), Gaps = 10/211 (4%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +CTD+DEC+ +P  C  GQC N  G Y C C   +    D   C D  +      + L  
Sbjct: 1366 SCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG 1425

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGGPGYQPVLEP 122
              E  + S     D   +      G    N C+      G  A   +C    G       
Sbjct: 1426 TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHA---VCTNTAGSFKCSCS 1482

Query: 123  PSYV---VTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            P ++   +   D+DEC+    +C+ H  C NT GS+ C C  G++               
Sbjct: 1483 PGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT-GDGFTCTDLDECSE 1541

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              ++CG G C N PG Y C C  G+V   +G
Sbjct: 1542 NLNLCGNGQCLNAPGGYRCECDMGFVPSADG 1572



 Score = 87.4 bits (207), Expect = 4e-17
 Identities = 62/213 (29%), Positives = 84/213 (39%), Gaps = 22/213 (10%)

Query: 6    CTDVDECK-SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            CTD++EC+    +C ++  C NT GS+ C C P +  + DG  C D  +          +
Sbjct: 1451 CTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDGIKCTDLDECS--------N 1500

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNY-C---DPCPEPGSEAYRQLCPGGPG-YQP 118
            GT  C    +         C C  G     + C   D C E  +      C   PG Y+ 
Sbjct: 1501 GTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRC 1560

Query: 119  VLE----PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
              +    P +      DIDEC+    +C  GTC N  G F C C  G+ L          
Sbjct: 1561 ECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDV 1619

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMP 207
                 P  C  G C N PGSY+C CP  +   P
Sbjct: 1620 NECLDPTTCISGNCVNTPGSYICDCPPDFELNP 1652



 Score = 86.2 bits (204), Expect = 8e-17
 Identities = 61/208 (29%), Positives = 78/208 (37%), Gaps = 19/208 (9%)

Query: 6    CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C DV+EC  +P  C  G C NT+GS+ C C   Y      T C D  +           G
Sbjct: 1409 CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEI--------G 1460

Query: 65   TETCRDSDELSEDGTMAACCCSVG-AAWGNYC---DPCPEPGSEAYRQL--CPGGPGYQP 118
               C      +       C CS G    G  C   D C   G+    Q   C    G   
Sbjct: 1461 AHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSN-GTHMCSQHADCKNTMGSYR 1519

Query: 119  VLEPPSYV---VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             L    Y     T  D+DEC+ +  LC +G C N  G + C C  G+  +          
Sbjct: 1520 CLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDID 1579

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                P++C  G C NLPG + C C  GY
Sbjct: 1580 ECSLPNICVFGTCHNLPGLFRCECEIGY 1607



 Score = 85.4 bits (202), Expect = 1e-16
 Identities = 54/159 (33%), Positives = 72/159 (45%), Gaps = 20/159 (12%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D+DEC+S   C  G C N+ GS+ C C     L    T C ++ K  C+  V    G 
Sbjct: 936  CEDIDECES-SPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVI--DG- 991

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSY 125
               R    ++     + CC S+GAAWG+ C  C          +C  G GY  +      
Sbjct: 992  ---RCEININGATLKSQCCSSLGAAWGSPCTLC------QVDPIC--GKGYSRIKG---- 1036

Query: 126  VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
                 DIDEC    G+C +G C NT GSF C C +G +L
Sbjct: 1037 -TQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTL 1074



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 72/236 (30%), Positives = 93/236 (39%), Gaps = 40/236 (16%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-----GKV 59
           C D+DEC + P  C+ G+C NT  SY C+CPP +    DGT C D R   CY     G+ 
Sbjct: 417 CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRC 476

Query: 60  DLR-----SGTETCRDSDELSEDG-TMAACCCSVGAA--WGNYCD-PCPEPGSEAYRQ-- 108
             +     +  + C D+      G T+A   C + A   +   C  P   PG   Y    
Sbjct: 477 SNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPP 536

Query: 109 ------LCPGGPGYQP-----VLEPP-SY---------VVTLADIDECAAHEGLCAHGTC 147
                 + P  PG+ P     V  PP  Y         V+ +   D C     LC +G C
Sbjct: 537 LGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRC 596

Query: 148 TNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             T GS+ C C  G+ L               P  C  G C N  GSY C C  GY
Sbjct: 597 IPTPGSYRCECNKGFQLDLRGECIDVDECEKNP--CAGGECINNQGSYTCQCRAGY 650



 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 68/218 (31%), Positives = 95/218 (43%), Gaps = 24/218 (11%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----CY 56
            G +C D+DEC + Q +CQ+  C+NT G +TC+CPP +      T+C D+ +       C 
Sbjct: 2611 GRSCKDLDECATKQHNCQF-LCVNTIGGFTCKCPPGF--TQHHTSCIDNNECTSDINLCG 2667

Query: 57   GKVDLRS--GTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
             K   ++  G+ TC      S D T  + C  V    GN+ C    +     YR  CP  
Sbjct: 2668 SKGICQNTPGSFTCECQRGFSLDQT-GSSCEDVDECEGNHRCQHGCQNIIGGYRCSCP-- 2724

Query: 114  PGYQPVLEPPSYVVTLADIDEC-AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
             GY    +    V    D +EC +AH  +C   +C NT GS+ C C AG+          
Sbjct: 2725 QGYLQHYQWNQCV----DENECLSAH--ICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ 2778

Query: 173  XXXXXXRPDV-CGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       C  G C N  G Y+C CP GY  +  G
Sbjct: 2779 DINECGSAQAPCSYG-CSNTEGGYLCGCPPGYFRIGQG 2815



 Score = 83.0 bits (196), Expect = 8e-16
 Identities = 63/214 (29%), Positives = 85/214 (39%), Gaps = 26/214 (12%)

Query: 6    CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D++EC+ S   C  G+C+N  G Y C C P Y    D   C D  +        +  G
Sbjct: 1284 CIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSI-----MNGG 1338

Query: 65   TET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS-EAYRQLCPGG-----PGYQ 117
             ET C +S+   E      C C  G A       C +    E    +C GG     PG  
Sbjct: 1339 CETFCTNSEGSYE------CSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEY 1392

Query: 118  PVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS-LAPXXXXX 171
              L    ++      T  D++EC  +  +C  GTC NT GSF+C C  G+S         
Sbjct: 1393 RCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1452

Query: 172  XXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYV 204
                       CG   VC N  GS+ C C  G++
Sbjct: 1453 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI 1486



 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 18/212 (8%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----C-YGKVD 60
            D++ECK  P  C +G+C NT GS+ CRC   + L S+   C D  + R     C  G+  
Sbjct: 1159 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1218

Query: 61   LRSGTETCRDSDELSEDG-TMAACCCSVGAAWGN--YCDPCPEPGSE-AYRQLCPGGPGY 116
               G   C+  DE  E G  M   C  +     +   C       +E +YR  CP  PG+
Sbjct: 1219 NTPGDFECK-CDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECP--PGH 1275

Query: 117  QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
            Q  L P   +    DI+EC     LC +G C N  G + C C  G+   P          
Sbjct: 1276 Q--LSPN--ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1331

Query: 177  XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                +      C N  GSY C C  G+  MP+
Sbjct: 1332 CSIMNGGCETFCTNSEGSYECSCQPGFALMPD 1363



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 63/222 (28%), Positives = 92/222 (41%), Gaps = 21/222 (9%)

Query: 5    NCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            N  D+DECK     C+ G+C+N +GSY C C   Y     GT+C D  +     K     
Sbjct: 2530 NGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPK----P 2585

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGGPGYQP 118
                C++++   +      C C  G      G  C    E  ++ +  + LC    G   
Sbjct: 2586 CNFICKNTEGSYQ------CSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFT 2639

Query: 119  VLEPPSYV---VTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
               PP +     +  D +EC +   LC + G C NT GSF C C  G+SL          
Sbjct: 2640 CKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDV 2699

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
                    C  G C+N+ G Y C CP+GY+     +Q + +N
Sbjct: 2700 DECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDEN 2740



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 59/209 (28%), Positives = 86/209 (41%), Gaps = 18/209 (8%)

Query: 3    GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCY 56
            G +C D++EC ++P+ C +  C NT+GSY C CP  Y L  DG +C D     +++  C 
Sbjct: 2570 GTSCVDLNECNQAPKPCNF-ICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ 2628

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG--P 114
                   G  TC+     ++  T     C       +  + C   GS+   Q  PG    
Sbjct: 2629 FLCVNTIGGFTCKCPPGFTQHHT----SCIDNNECTSDINLC---GSKGICQNTPGSFTC 2681

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
              Q          +  D+DEC  +   C HG C N  G + C+C  G+            
Sbjct: 2682 ECQRGFSLDQTGSSCEDVDECEGNH-RCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDE 2739

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                   +CG   C N  GSY C+CP G+
Sbjct: 2740 NECLSAHICGGASCHNTLGSYKCMCPAGF 2768



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 49/166 (29%), Positives = 74/166 (44%), Gaps = 21/166 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC+    C  G+CIN QGSYTC+C   Y+     T C D  +    G++      
Sbjct: 619 CIDVDECEK-NPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRI------ 671

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG------PGYQPV 119
             C +   ++ DG+   C C+ G         C +    + R +C  G        ++ +
Sbjct: 672 --CNNGRCINTDGSF-HCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCI 728

Query: 120 LEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
            +P   + +      DI+EC    G+C +G C NT GS+ C C  G
Sbjct: 729 CKPGFQLASDGRYCKDINECET-PGICMNGRCVNTDGSYRCECFPG 773



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 18/176 (10%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARC 55
            + G  C D DEC     C  G C N  G + C C   +E        D   C  +     
Sbjct: 2290 LAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCA 2349

Query: 56   YGKVDLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR----QLC 110
            +  V+     E  C     L ED  M  C        G +   C E   E        +C
Sbjct: 2350 FRCVNTYGSYECKCPVGYVLREDRRM--CKDEDECEEGKH--DCTEKQMECKNLIGTYMC 2405

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              GPGYQ   +    V    D +EC    G+C +G C NT GS+ C C  G++ +P
Sbjct: 2406 ICGPGYQRRPDGEGCV----DENECQTKPGICENGRCLNTRGSYTCECNDGFTASP 2457



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/177 (30%), Positives = 71/177 (40%), Gaps = 26/177 (14%)

Query: 3    GFNCTDVDECKS-PQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G  CTD+DEC +    C Q+  C NT GSY C C   Y    DG  C D  +  C   ++
Sbjct: 1489 GIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDE--CSENLN 1544

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCPGGP 114
            L      C +   L+  G    C C +G   +A G  C   D C  P    +   C   P
Sbjct: 1545 L------CGNGQCLNAPGGY-RCECDMGFVPSADGKACEDIDECSLPNICVF-GTCHNLP 1596

Query: 115  GYQPVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
            G         Y +        D++EC      C  G C NT GS++C C   + L P
Sbjct: 1597 GLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCISGNCVNTPGSYICDCPPDFELNP 1652



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 36/119 (30%), Positives = 49/119 (41%), Gaps = 8/119 (6%)

Query: 95  CDPCPEPGSEAYRQ----LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNT 150
           C+  P  G E         C    GYQ  L          DIDEC  +  +C +G C NT
Sbjct: 625 CEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTE----CRDIDECLQNGRICNNGRCINT 680

Query: 151 FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            GSF C C AG+ +                ++C  G+C N  GS+ C+C  G+    +G
Sbjct: 681 DGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDG 739



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 59/213 (27%), Positives = 81/213 (38%), Gaps = 25/213 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D++EC   P+ C  G C N  GSY C CPP Y L ++   C D  +  C  + ++
Sbjct: 2099 GRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE--KCEDIDE--CVEEPEI 2154

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
                 TC +++     G+   C C  G +  +    C +           GG    P   
Sbjct: 2155 -CALGTCSNTE-----GSFK-CLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSR 2207

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTC----TNTFGSF--VCTCGAGWSLAPXXXXXXXXX 175
              S        + C A +G      C    T    +F  +C  G+G  + P         
Sbjct: 2208 NHSKQ------ECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDE 2261

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                PDVC  G C N  GSY C CP GY    N
Sbjct: 2262 CK-EPDVCKHGQCINTDGSYRCECPFGYTLAGN 2293



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 47/162 (29%), Positives = 71/162 (43%), Gaps = 14/162 (8%)

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-GNYC---DPCPEPGSEAYRQLCPGG-PGYQPVL 120
            + C+    ++ DG+   C C  G    GN C   D C   G+      C     G++   
Sbjct: 2266 DVCKHGQCINTDGSYR-CECPFGYTLAGNECVDTDEC-SVGNPCGNGTCKNVIGGFECTC 2323

Query: 121  EP---PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX- 176
            E    P  ++T  DI+ECA +  LCA   C NT+GS+ C C  G+ L             
Sbjct: 2324 EEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDEC 2382

Query: 177  -XXRPDVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
               + D     + C+NL G+Y+C+C  GY   P+G   + +N
Sbjct: 2383 EEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDEN 2424



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 24/47 (51%), Positives = 29/47 (61%), Gaps = 2/47 (4%)

Query: 5    NCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
            +C DVDEC S     C+ GQCINT GS+ C+C   YE+  DG  C D
Sbjct: 2058 DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVD 2104



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 22/45 (48%), Positives = 28/45 (62%), Gaps = 1/45 (2%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           C DVDEC++ P  CQ G CINT GS+ C+CP  ++L      C D
Sbjct: 375 CQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCED 419



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 55/208 (26%), Positives = 69/208 (33%), Gaps = 18/208 (8%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCY-G 57
            G  C D+DEC  P  C +G C N  G + C C   YEL   G  C D  +      C  G
Sbjct: 1572 GKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISG 1631

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
                  G+  C    +   + T   C   V    GN C     P  +     C    G  
Sbjct: 1632 NCVNTPGSYICDCPPDFELNPTRVGC---VDTRSGN-CYLDIRPRGDNGDTACSNEIGVG 1687

Query: 118  PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFG-SFVCTCGAGWSLAPXXXXXXXXXX 176
              +   S   +L       A    C      NT     +C  G G+   P          
Sbjct: 1688 --VSKASCCCSLG-----KAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDE 1740

Query: 177  XXR-PDVCGPGVCRNLPGSYVCLCPEGY 203
                P +C  G C N  GS+ C CP GY
Sbjct: 1741 CQELPGLCQGGKCINTFGSFQCRCPTGY 1768



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 8/57 (14%)

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
           CP G  Y+P L+      T  DIDEC +    C +G C N+ GSF+C C +  +L P
Sbjct: 923 CPKGFIYKPDLK------TCEDIDECESSP--CINGVCKNSPGSFICECSSESTLDP 971


>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
          Length = 2871

 Score =  197 bits (481), Expect = 2e-50
 Identities = 88/208 (42%), Positives = 112/208 (53%), Gaps = 4/208 (1%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G NCTDV+EC  P +C  G C+NT GSY C CPP++EL      C D+R   CY  +  R
Sbjct: 1482 GGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPR 1541

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
                    S+E+    + A+CCCS+G AWG  C+ CP   +  Y+ LCPGG G++P   P
Sbjct: 1542 GDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRP--NP 1599

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
                V L DIDEC    GLC  G C NTFGSF C C  G+ L               P +
Sbjct: 1600 --ITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGI 1657

Query: 183  CGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
            CGPG C N  G+Y C+CP  Y+ +  G+
Sbjct: 1658 CGPGTCYNTVGNYTCICPPDYMQVNGGN 1685



 Score =  161 bits (391), Expect = 2e-39
 Identities = 82/204 (40%), Positives = 106/204 (51%), Gaps = 10/204 (4%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D+DEC+  P  C+ G C+NT+GS+ C+CP    L + G  C D R   C+    L
Sbjct: 905  GTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCF----L 960

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGYQPVL 120
            R   E C  +  ++    M ACCCSVGAAWG   C+ CP   +  Y +LCP GPG+    
Sbjct: 961  RYEDEEC--TLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFA-TK 1017

Query: 121  EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXR 179
            E  +      DI+EC     LC HG C NT GSF C C +G++L +              
Sbjct: 1018 EITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRIS 1077

Query: 180  PDVCGPGVCRNLPGSYVCLCPEGY 203
            PD+CG G C N PG + C C EGY
Sbjct: 1078 PDLCGRGQCVNTPGDFECKCDEGY 1101



 Score =  148 bits (359), Expect = 1e-35
 Identities = 76/204 (37%), Positives = 104/204 (50%), Gaps = 16/204 (7%)

Query: 6    CTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC + P+ C  G C NT+GS+ C CP  + L S G  C D R + CY K      
Sbjct: 2011 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKF----- 2065

Query: 65   TETCRDSDELSEDGTMAACCCSV-GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPP 123
             E  + S   S + +   CCC++ G  WG+ C+ CP    EA+RQ+CP G G   ++ P 
Sbjct: 2066 -EGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGI--IVGPD 2122

Query: 124  SYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC 183
               V   D+DEC   + +C HG C NT GS+ C C  G++LA              P  C
Sbjct: 2123 DSAV---DMDECKEPD-VCKHGQCINTDGSYRCECPFGYTLAGNECVDTDECSVGNP--C 2176

Query: 184  GPGVCRNLPGSYVCLCPEGYVAMP 207
            G G C+N+ G + C C EG+   P
Sbjct: 2177 GNGTCKNVIGGFECTCEEGFEPGP 2200



 Score =  137 bits (331), Expect = 3e-32
 Identities = 71/209 (33%), Positives = 102/209 (48%), Gaps = 18/209 (8%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  C D++EC++P  C  G+C+NT GSY C C P   +  DG  C D+  ++ CYG    
Sbjct: 608 GRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYG---- 663

Query: 62  RSGTETCRDSDELSEDGTMAACCC-SVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
             G +  +    L    T + CCC S   A+G  C PCP   S  Y+ LC  GPG     
Sbjct: 664 --GYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAG 721

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXR 179
                    +DI+ECA    +C +G C N  G++ C C +G+ + +              
Sbjct: 722 ---------SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLN 772

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
             +C  G CRN PGS+VC CP+G++  P+
Sbjct: 773 SLLCDNGQCRNTPGSFVCTCPKGFIYKPD 801



 Score =  137 bits (331), Expect = 3e-32
 Identities = 69/209 (33%), Positives = 104/209 (49%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D +EC++ P  C+ G+C+NT+GSYTC C   +    +   C D+R+  C+ +V L
Sbjct: 2286 GEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEV-L 2344

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++    C+         T + CCC  G  WG +C+ CP  G+ A+++LCP G G      
Sbjct: 2345 QN---MCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRG------ 2395

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               ++   ADIDEC     +C +G C N  GS+ C C  G++                 P
Sbjct: 2396 ---FMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAP 2452

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GSY C CP+GY+   +G
Sbjct: 2453 KPCN-FICKNTEGSYQCSCPKGYILQEDG 2480



 Score =  136 bits (330), Expect = 5e-32
 Identities = 75/202 (37%), Positives = 98/202 (48%), Gaps = 12/202 (5%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C DV+EC++P  C  G C NT G+YTC CPP+Y  V+ G  C D R++ CY   +  +  
Sbjct: 1646 CDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYR--NYYADN 1703

Query: 66   ETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPG-GPGYQPVLEP 122
            +TC    EL  + T   CCCS  +G AW   C+ CP P ++ +  LC    PG+  V++ 
Sbjct: 1704 QTC--DGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGF--VID- 1758

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
              Y     DIDEC    G+C +G C N  GSF C C  G+                   V
Sbjct: 1759 -IYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV 1817

Query: 183  CGPGV-CRNLPGSYVCLCPEGY 203
            C     C N  GSY C C  GY
Sbjct: 1818 CQRNAECINTAGSYRCDCKPGY 1839



 Score =  105 bits (253), Expect = 1e-22
 Identities = 66/210 (31%), Positives = 91/210 (43%), Gaps = 23/210 (10%)

Query: 6    CTDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC++   CQ   +CINT GSY C C P Y   S G         +C  + + +  
Sbjct: 1806 CEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG---------QCNDRNECQEI 1856

Query: 65   TETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE--- 121
               C     +   G+   C C  G    +    C +  +E  R  C  G     +     
Sbjct: 1857 PNICSHGQCIDTVGSFY-CLCHTGFKTNDDQTMCLDI-NECERDACGNGTCRNTIGSFNC 1914

Query: 122  --PPSYVVT----LADIDECAAHEG-LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
                 ++++      D+DECA+  G LC +G C NT GSF C C  G+ +AP        
Sbjct: 1915 RCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDI 1974

Query: 175  XX-XXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  C PG C+NL GSY C+CP GY
Sbjct: 1975 NECLLEPRKCAPGTCQNLDGSYRCICPPGY 2004



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 67/214 (31%), Positives = 93/214 (43%), Gaps = 22/214 (10%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  GQC+NT G + C+C   YE      + +   K  C    + + 
Sbjct: 1067 NCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYE------SGFMMMK-NCMDIDECQR 1119

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS-EAYRQLCPGGP------GY 116
                CR     + +G+   C C  G         C +    E    LCP G        Y
Sbjct: 1120 DPLLCRGGVCHNTEGSYR-CECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKY 1178

Query: 117  QPVLEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
            Q    P  +         DIDEC+   G C    CTN+ GS+ C+C  G++L P      
Sbjct: 1179 QCACNPGYHSTPDRLFCVDIDECSIMNGGC-ETFCTNSEGSYECSCQPGFALMPDQRSCT 1237

Query: 173  XXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                    P++C  G C N+PG Y CLC +G++A
Sbjct: 1238 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMA 1271



 Score = 96.7 bits (230), Expect = 6e-20
 Identities = 72/226 (31%), Positives = 93/226 (41%), Gaps = 28/226 (12%)

Query: 2    PGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            P  +  D+DECK P  C++GQCINT GSY C CP  Y L   G  C D+ +      V  
Sbjct: 2121 PDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYTLA--GNECVDTDEC----SVGN 2174

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY--CDPCPE----PGSEAYRQLCPGGPG 115
              G  TC++     E      C C  G   G    C+   E    P   A+R  C    G
Sbjct: 2175 PCGNGTCKNVIGGFE------CTCEEGFEPGPMMTCEDINECAQNPLLCAFR--CVNTYG 2226

Query: 116  YQPVLEPPSYVV-----TLADIDECAAHEGLCAHG--TCTNTFGSFVCTCGAGWSLAPXX 168
                  P  YV+        D DEC   +  C      C N  G+++C CG G+   P  
Sbjct: 2227 SYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDG 2286

Query: 169  XX-XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
                       +P +C  G C N  GSY C C +G+ A PN  + L
Sbjct: 2287 EGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 2332



 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 69/212 (32%), Positives = 91/212 (42%), Gaps = 16/212 (7%)

Query: 6    CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCYGKVD 60
            C D +EC+  P  C +GQCI+T GS+ C C   ++   D T C D     R A   G   
Sbjct: 1847 CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCR 1906

Query: 61   LRSGTETCRDSDE--LSEDGTMAACC-CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
               G+  CR +    LS +        C+ G   GN C       +    Q C    GY+
Sbjct: 1907 NTIGSFNCRCNHGFILSHNNDCIDVDECASGN--GNLCRNGQCINTVGSFQ-CQCNEGYE 1963

Query: 118  PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
              + P     T  DI+EC      CA GTC N  GS+ C C  G+SL             
Sbjct: 1964 --VAPDGR--TCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL-QNEKCEDIDECV 2018

Query: 178  XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              P++C  G C N  GS+ CLCPEG+    +G
Sbjct: 2019 EEPEICALGTCSNTEGSFKCLCPEGFSLSSSG 2050



 Score = 87.4 bits (207), Expect = 4e-17
 Identities = 58/211 (27%), Positives = 83/211 (39%), Gaps = 10/211 (4%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +CTD+DEC+ +P  C  GQC N  G Y C C   +    D   C D  +      + L  
Sbjct: 1235 SCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG 1294

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGGPGYQPVLEP 122
              E  + S     D   +      G    N C+      G  A   +C    G       
Sbjct: 1295 TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHA---VCTNTAGSFKCSCS 1351

Query: 123  PSYV---VTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            P ++   +   D+DEC+    +C+ H  C NT GS+ C C  G++               
Sbjct: 1352 PGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT-GDGFTCTDLDECSE 1410

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              ++CG G C N PG Y C C  G+V   +G
Sbjct: 1411 NLNLCGNGQCLNAPGGYRCECDMGFVPSADG 1441



 Score = 87.4 bits (207), Expect = 4e-17
 Identities = 62/213 (29%), Positives = 84/213 (39%), Gaps = 22/213 (10%)

Query: 6    CTDVDECK-SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            CTD++EC+    +C ++  C NT GS+ C C P +  + DG  C D  +          +
Sbjct: 1320 CTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDGIKCTDLDECS--------N 1369

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNY-C---DPCPEPGSEAYRQLCPGGPG-YQP 118
            GT  C    +         C C  G     + C   D C E  +      C   PG Y+ 
Sbjct: 1370 GTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRC 1429

Query: 119  VLE----PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
              +    P +      DIDEC+    +C  GTC N  G F C C  G+ L          
Sbjct: 1430 ECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDV 1488

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMP 207
                 P  C  G C N PGSY+C CP  +   P
Sbjct: 1489 NECLDPTTCISGNCVNTPGSYICDCPPDFELNP 1521



 Score = 87.0 bits (206), Expect = 5e-17
 Identities = 48/134 (35%), Positives = 60/134 (44%), Gaps = 12/134 (8%)

Query: 79  TMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAH 138
           T   CC +VG AWG+ C+ CP        Q  P   G+ P +   +      D+DEC A 
Sbjct: 205 TKQLCCATVGRAWGHPCEMCPA-------QPHPCRRGFIPNIRTGA----CQDVDECQAI 253

Query: 139 EGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCGPGVCRNLPGSYVC 197
            GLC  G C NT GSF C C AG  L                P +C  G C N   SY C
Sbjct: 254 PGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFC 313

Query: 198 LCPEGYVAMPNGSQ 211
            CP G+   P+G++
Sbjct: 314 KCPPGFYTSPDGTR 327



 Score = 86.2 bits (204), Expect = 8e-17
 Identities = 61/208 (29%), Positives = 78/208 (37%), Gaps = 19/208 (9%)

Query: 6    CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C DV+EC  +P  C  G C NT+GS+ C C   Y      T C D  +           G
Sbjct: 1278 CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEI--------G 1329

Query: 65   TETCRDSDELSEDGTMAACCCSVG-AAWGNYC---DPCPEPGSEAYRQL--CPGGPGYQP 118
               C      +       C CS G    G  C   D C   G+    Q   C    G   
Sbjct: 1330 AHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSN-GTHMCSQHADCKNTMGSYR 1388

Query: 119  VLEPPSYV---VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             L    Y     T  D+DEC+ +  LC +G C N  G + C C  G+  +          
Sbjct: 1389 CLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDID 1448

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                P++C  G C NLPG + C C  GY
Sbjct: 1449 ECSLPNICVFGTCHNLPGLFRCECEIGY 1476



 Score = 85.4 bits (202), Expect = 1e-16
 Identities = 54/159 (33%), Positives = 72/159 (45%), Gaps = 20/159 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C D+DEC+S   C  G C N+ GS+ C C     L    T C ++ K  C+  V    G 
Sbjct: 805 CEDIDECES-SPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVI--DG- 860

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSY 125
              R    ++     + CC S+GAAWG+ C  C          +C  G GY  +      
Sbjct: 861 ---RCEININGATLKSQCCSSLGAAWGSPCTLC------QVDPIC--GKGYSRIKG---- 905

Query: 126 VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
                DIDEC    G+C +G C NT GSF C C +G +L
Sbjct: 906 -TQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTL 943



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 72/236 (30%), Positives = 93/236 (39%), Gaps = 40/236 (16%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-----GKV 59
           C D+DEC + P  C+ G+C NT  SY C+CPP +    DGT C D R   CY     G+ 
Sbjct: 286 CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRC 345

Query: 60  DLR-----SGTETCRDSDELSEDG-TMAACCCSVGAA--WGNYCD-PCPEPGSEAYRQ-- 108
             +     +  + C D+      G T+A   C + A   +   C  P   PG   Y    
Sbjct: 346 SNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPP 405

Query: 109 ------LCPGGPGYQP-----VLEPP-SY---------VVTLADIDECAAHEGLCAHGTC 147
                 + P  PG+ P     V  PP  Y         V+ +   D C     LC +G C
Sbjct: 406 LGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRC 465

Query: 148 TNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             T GS+ C C  G+ L               P  C  G C N  GSY C C  GY
Sbjct: 466 IPTPGSYRCECNKGFQLDLRGECIDVDECEKNP--CAGGECINNQGSYTCQCRAGY 519



 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 68/218 (31%), Positives = 95/218 (43%), Gaps = 24/218 (11%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----CY 56
            G +C D+DEC + Q +CQ+  C+NT G +TC+CPP +      T+C D+ +       C 
Sbjct: 2480 GRSCKDLDECATKQHNCQF-LCVNTIGGFTCKCPPGF--TQHHTSCIDNNECTSDINLCG 2536

Query: 57   GKVDLRS--GTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
             K   ++  G+ TC      S D T  + C  V    GN+ C    +     YR  CP  
Sbjct: 2537 SKGICQNTPGSFTCECQRGFSLDQT-GSSCEDVDECEGNHRCQHGCQNIIGGYRCSCP-- 2593

Query: 114  PGYQPVLEPPSYVVTLADIDEC-AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
             GY    +    V    D +EC +AH  +C   +C NT GS+ C C AG+          
Sbjct: 2594 QGYLQHYQWNQCV----DENECLSAH--ICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ 2647

Query: 173  XXXXXXRPDV-CGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       C  G C N  G Y+C CP GY  +  G
Sbjct: 2648 DINECGSAQAPCSYG-CSNTEGGYLCGCPPGYFRIGQG 2684



 Score = 83.0 bits (196), Expect = 8e-16
 Identities = 63/214 (29%), Positives = 85/214 (39%), Gaps = 26/214 (12%)

Query: 6    CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D++EC+ S   C  G+C+N  G Y C C P Y    D   C D  +        +  G
Sbjct: 1153 CIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSI-----MNGG 1207

Query: 65   TET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS-EAYRQLCPGG-----PGYQ 117
             ET C +S+   E      C C  G A       C +    E    +C GG     PG  
Sbjct: 1208 CETFCTNSEGSYE------CSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEY 1261

Query: 118  PVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS-LAPXXXXX 171
              L    ++      T  D++EC  +  +C  GTC NT GSF+C C  G+S         
Sbjct: 1262 RCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321

Query: 172  XXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYV 204
                       CG   VC N  GS+ C C  G++
Sbjct: 1322 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI 1355



 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 18/212 (8%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----C-YGKVD 60
            D++ECK  P  C +G+C NT GS+ CRC   + L S+   C D  + R     C  G+  
Sbjct: 1028 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087

Query: 61   LRSGTETCRDSDELSEDG-TMAACCCSVGAAWGN--YCDPCPEPGSE-AYRQLCPGGPGY 116
               G   C+  DE  E G  M   C  +     +   C       +E +YR  CP  PG+
Sbjct: 1088 NTPGDFECK-CDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECP--PGH 1144

Query: 117  QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
            Q  L P   +    DI+EC     LC +G C N  G + C C  G+   P          
Sbjct: 1145 Q--LSPN--ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1200

Query: 177  XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                +      C N  GSY C C  G+  MP+
Sbjct: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFALMPD 1232



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 63/222 (28%), Positives = 92/222 (41%), Gaps = 21/222 (9%)

Query: 5    NCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            N  D+DECK     C+ G+C+N +GSY C C   Y     GT+C D  +     K     
Sbjct: 2399 NGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPK----P 2454

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGGPGYQP 118
                C++++   +      C C  G      G  C    E  ++ +  + LC    G   
Sbjct: 2455 CNFICKNTEGSYQ------CSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFT 2508

Query: 119  VLEPPSYV---VTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
               PP +     +  D +EC +   LC + G C NT GSF C C  G+SL          
Sbjct: 2509 CKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDV 2568

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
                    C  G C+N+ G Y C CP+GY+     +Q + +N
Sbjct: 2569 DECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDEN 2609



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 59/209 (28%), Positives = 86/209 (41%), Gaps = 18/209 (8%)

Query: 3    GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCY 56
            G +C D++EC ++P+ C +  C NT+GSY C CP  Y L  DG +C D     +++  C 
Sbjct: 2439 GTSCVDLNECNQAPKPCNF-ICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ 2497

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG--P 114
                   G  TC+     ++  T     C       +  + C   GS+   Q  PG    
Sbjct: 2498 FLCVNTIGGFTCKCPPGFTQHHT----SCIDNNECTSDINLC---GSKGICQNTPGSFTC 2550

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
              Q          +  D+DEC  +   C HG C N  G + C+C  G+            
Sbjct: 2551 ECQRGFSLDQTGSSCEDVDECEGNH-RCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDE 2608

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                   +CG   C N  GSY C+CP G+
Sbjct: 2609 NECLSAHICGGASCHNTLGSYKCMCPAGF 2637



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 49/166 (29%), Positives = 74/166 (44%), Gaps = 21/166 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC+    C  G+CIN QGSYTC+C   Y+     T C D  +    G++      
Sbjct: 488 CIDVDECEK-NPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRI------ 540

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG------PGYQPV 119
             C +   ++ DG+   C C+ G         C +    + R +C  G        ++ +
Sbjct: 541 --CNNGRCINTDGSF-HCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCI 597

Query: 120 LEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
            +P   + +      DI+EC    G+C +G C NT GS+ C C  G
Sbjct: 598 CKPGFQLASDGRYCKDINECET-PGICMNGRCVNTDGSYRCECFPG 642



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 18/176 (10%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARC 55
            + G  C D DEC     C  G C N  G + C C   +E        D   C  +     
Sbjct: 2159 LAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCA 2218

Query: 56   YGKVDLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR----QLC 110
            +  V+     E  C     L ED  M  C        G +   C E   E        +C
Sbjct: 2219 FRCVNTYGSYECKCPVGYVLREDRRM--CKDEDECEEGKH--DCTEKQMECKNLIGTYMC 2274

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              GPGYQ   +    V    D +EC    G+C +G C NT GS+ C C  G++ +P
Sbjct: 2275 ICGPGYQRRPDGEGCV----DENECQTKPGICENGRCLNTRGSYTCECNDGFTASP 2326



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/177 (30%), Positives = 71/177 (40%), Gaps = 26/177 (14%)

Query: 3    GFNCTDVDECKS-PQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G  CTD+DEC +    C Q+  C NT GSY C C   Y    DG  C D  +  C   ++
Sbjct: 1358 GIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDE--CSENLN 1413

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCPGGP 114
            L      C +   L+  G    C C +G   +A G  C   D C  P    +   C   P
Sbjct: 1414 L------CGNGQCLNAPGGY-RCECDMGFVPSADGKACEDIDECSLPNICVF-GTCHNLP 1465

Query: 115  GYQPVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
            G         Y +        D++EC      C  G C NT GS++C C   + L P
Sbjct: 1466 GLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCISGNCVNTPGSYICDCPPDFELNP 1521



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 36/119 (30%), Positives = 49/119 (41%), Gaps = 8/119 (6%)

Query: 95  CDPCPEPGSEAYRQ----LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNT 150
           C+  P  G E         C    GYQ  L          DIDEC  +  +C +G C NT
Sbjct: 494 CEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTE----CRDIDECLQNGRICNNGRCINT 549

Query: 151 FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            GSF C C AG+ +                ++C  G+C N  GS+ C+C  G+    +G
Sbjct: 550 DGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDG 608



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 59/213 (27%), Positives = 81/213 (38%), Gaps = 25/213 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D++EC   P+ C  G C N  GSY C CPP Y L ++   C D  +  C  + ++
Sbjct: 1968 GRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE--KCEDIDE--CVEEPEI 2023

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
                 TC +++     G+   C C  G +  +    C +           GG    P   
Sbjct: 2024 -CALGTCSNTE-----GSFK-CLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSR 2076

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTC----TNTFGSF--VCTCGAGWSLAPXXXXXXXXX 175
              S        + C A +G      C    T    +F  +C  G+G  + P         
Sbjct: 2077 NHSKQ------ECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDE 2130

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                PDVC  G C N  GSY C CP GY    N
Sbjct: 2131 CK-EPDVCKHGQCINTDGSYRCECPFGYTLAGN 2162



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 47/162 (29%), Positives = 71/162 (43%), Gaps = 14/162 (8%)

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-GNYC---DPCPEPGSEAYRQLCPGG-PGYQPVL 120
            + C+    ++ DG+   C C  G    GN C   D C   G+      C     G++   
Sbjct: 2135 DVCKHGQCINTDGSYR-CECPFGYTLAGNECVDTDEC-SVGNPCGNGTCKNVIGGFECTC 2192

Query: 121  EP---PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX- 176
            E    P  ++T  DI+ECA +  LCA   C NT+GS+ C C  G+ L             
Sbjct: 2193 EEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDEC 2251

Query: 177  -XXRPDVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
               + D     + C+NL G+Y+C+C  GY   P+G   + +N
Sbjct: 2252 EEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDEN 2293



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 24/47 (51%), Positives = 29/47 (61%), Gaps = 2/47 (4%)

Query: 5    NCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
            +C DVDEC S     C+ GQCINT GS+ C+C   YE+  DG  C D
Sbjct: 1927 DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVD 1973



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 22/45 (48%), Positives = 28/45 (62%), Gaps = 1/45 (2%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           C DVDEC++ P  CQ G CINT GS+ C+CP  ++L      C D
Sbjct: 244 CQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCED 288



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 55/208 (26%), Positives = 69/208 (33%), Gaps = 18/208 (8%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCY-G 57
            G  C D+DEC  P  C +G C N  G + C C   YEL   G  C D  +      C  G
Sbjct: 1441 GKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISG 1500

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
                  G+  C    +   + T   C   V    GN C     P  +     C    G  
Sbjct: 1501 NCVNTPGSYICDCPPDFELNPTRVGC---VDTRSGN-CYLDIRPRGDNGDTACSNEIGVG 1556

Query: 118  PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFG-SFVCTCGAGWSLAPXXXXXXXXXX 176
              +   S   +L       A    C      NT     +C  G G+   P          
Sbjct: 1557 --VSKASCCCSLG-----KAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDE 1609

Query: 177  XXR-PDVCGPGVCRNLPGSYVCLCPEGY 203
                P +C  G C N  GS+ C CP GY
Sbjct: 1610 CQELPGLCQGGKCINTFGSFQCRCPTGY 1637



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 8/57 (14%)

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
           CP G  Y+P L+      T  DIDEC +    C +G C N+ GSF+C C +  +L P
Sbjct: 792 CPKGFIYKPDLK------TCEDIDECESSP--CINGVCKNSPGSFICECSSESTLDP 840


>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
          Length = 2871

 Score =  197 bits (481), Expect = 2e-50
 Identities = 88/208 (42%), Positives = 112/208 (53%), Gaps = 4/208 (1%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G NCTDV+EC  P +C  G C+NT GSY C CPP++EL      C D+R   CY  +  R
Sbjct: 1482 GGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPR 1541

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
                    S+E+    + A+CCCS+G AWG  C+ CP   +  Y+ LCPGG G++P   P
Sbjct: 1542 GDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRP--NP 1599

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
                V L DIDEC    GLC  G C NTFGSF C C  G+ L               P +
Sbjct: 1600 --ITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGI 1657

Query: 183  CGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
            CGPG C N  G+Y C+CP  Y+ +  G+
Sbjct: 1658 CGPGTCYNTVGNYTCICPPDYMQVNGGN 1685



 Score =  161 bits (391), Expect = 2e-39
 Identities = 82/204 (40%), Positives = 106/204 (51%), Gaps = 10/204 (4%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D+DEC+  P  C+ G C+NT+GS+ C+CP    L + G  C D R   C+    L
Sbjct: 905  GTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCF----L 960

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGYQPVL 120
            R   E C  +  ++    M ACCCSVGAAWG   C+ CP   +  Y +LCP GPG+    
Sbjct: 961  RYEDEEC--TLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFA-TK 1017

Query: 121  EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXR 179
            E  +      DI+EC     LC HG C NT GSF C C +G++L +              
Sbjct: 1018 EITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRIS 1077

Query: 180  PDVCGPGVCRNLPGSYVCLCPEGY 203
            PD+CG G C N PG + C C EGY
Sbjct: 1078 PDLCGRGQCVNTPGDFECKCDEGY 1101



 Score =  147 bits (356), Expect = 3e-35
 Identities = 76/204 (37%), Positives = 103/204 (50%), Gaps = 16/204 (7%)

Query: 6    CTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC + P+ C  G C NT+GS+ C CP  + L S G  C D R + CY K      
Sbjct: 2011 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKF----- 2065

Query: 65   TETCRDSDELSEDGTMAACCCSV-GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPP 123
             E  + S   S + +   CCC++ G  WG+ C+ CP    EA+RQ+CP G G   ++ P 
Sbjct: 2066 -EGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGI--IVGPD 2122

Query: 124  SYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC 183
               V   D+DEC   + +C HG C NT GS+ C C  G+ LA              P  C
Sbjct: 2123 DSAV---DMDECKEPD-VCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNP--C 2176

Query: 184  GPGVCRNLPGSYVCLCPEGYVAMP 207
            G G C+N+ G + C C EG+   P
Sbjct: 2177 GNGTCKNVIGGFECTCEEGFEPGP 2200



 Score =  137 bits (331), Expect = 3e-32
 Identities = 71/209 (33%), Positives = 102/209 (48%), Gaps = 18/209 (8%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  C D++EC++P  C  G+C+NT GSY C C P   +  DG  C D+  ++ CYG    
Sbjct: 608 GRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYG---- 663

Query: 62  RSGTETCRDSDELSEDGTMAACCC-SVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
             G +  +    L    T + CCC S   A+G  C PCP   S  Y+ LC  GPG     
Sbjct: 664 --GYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAG 721

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXR 179
                    +DI+ECA    +C +G C N  G++ C C +G+ + +              
Sbjct: 722 ---------SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLN 772

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
             +C  G CRN PGS+VC CP+G++  P+
Sbjct: 773 SLLCDNGQCRNTPGSFVCTCPKGFIYKPD 801



 Score =  137 bits (331), Expect = 3e-32
 Identities = 69/209 (33%), Positives = 104/209 (49%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D +EC++ P  C+ G+C+NT+GSYTC C   +    +   C D+R+  C+ +V L
Sbjct: 2286 GEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEV-L 2344

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++    C+         T + CCC  G  WG +C+ CP  G+ A+++LCP G G      
Sbjct: 2345 QN---MCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRG------ 2395

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               ++   ADIDEC     +C +G C N  GS+ C C  G++                 P
Sbjct: 2396 ---FMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAP 2452

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GSY C CP+GY+   +G
Sbjct: 2453 KPCN-FICKNTEGSYQCSCPKGYILQEDG 2480



 Score =  136 bits (330), Expect = 5e-32
 Identities = 75/202 (37%), Positives = 98/202 (48%), Gaps = 12/202 (5%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C DV+EC++P  C  G C NT G+YTC CPP+Y  V+ G  C D R++ CY   +  +  
Sbjct: 1646 CDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYR--NYYADN 1703

Query: 66   ETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPG-GPGYQPVLEP 122
            +TC    EL  + T   CCCS  +G AW   C+ CP P ++ +  LC    PG+  V++ 
Sbjct: 1704 QTC--DGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGF--VID- 1758

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
              Y     DIDEC    G+C +G C N  GSF C C  G+                   V
Sbjct: 1759 -IYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV 1817

Query: 183  CGPGV-CRNLPGSYVCLCPEGY 203
            C     C N  GSY C C  GY
Sbjct: 1818 CQRNAECINTAGSYRCDCKPGY 1839



 Score =  105 bits (253), Expect = 1e-22
 Identities = 66/210 (31%), Positives = 91/210 (43%), Gaps = 23/210 (10%)

Query: 6    CTDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC++   CQ   +CINT GSY C C P Y   S G         +C  + + +  
Sbjct: 1806 CEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG---------QCNDRNECQEI 1856

Query: 65   TETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE--- 121
               C     +   G+   C C  G    +    C +  +E  R  C  G     +     
Sbjct: 1857 PNICSHGQCIDTVGSFY-CLCHTGFKTNDDQTMCLDI-NECERDACGNGTCRNTIGSFNC 1914

Query: 122  --PPSYVVT----LADIDECAAHEG-LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
                 ++++      D+DECA+  G LC +G C NT GSF C C  G+ +AP        
Sbjct: 1915 RCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDI 1974

Query: 175  XX-XXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  C PG C+NL GSY C+CP GY
Sbjct: 1975 NECLLEPRKCAPGTCQNLDGSYRCICPPGY 2004



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 67/214 (31%), Positives = 93/214 (43%), Gaps = 22/214 (10%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  GQC+NT G + C+C   YE      + +   K  C    + + 
Sbjct: 1067 NCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYE------SGFMMMK-NCMDIDECQR 1119

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS-EAYRQLCPGGP------GY 116
                CR     + +G+   C C  G         C +    E    LCP G        Y
Sbjct: 1120 DPLLCRGGVCHNTEGSYR-CECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKY 1178

Query: 117  QPVLEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
            Q    P  +         DIDEC+   G C    CTN+ GS+ C+C  G++L P      
Sbjct: 1179 QCACNPGYHSTPDRLFCVDIDECSIMNGGC-ETFCTNSEGSYECSCQPGFALMPDQRSCT 1237

Query: 173  XXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                    P++C  G C N+PG Y CLC +G++A
Sbjct: 1238 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMA 1271



 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 72/226 (31%), Positives = 93/226 (41%), Gaps = 28/226 (12%)

Query: 2    PGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            P  +  D+DECK P  C++GQCINT GSY C CP  Y L   G  C D+ +      V  
Sbjct: 2121 PDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDEC----SVGN 2174

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY--CDPCPE----PGSEAYRQLCPGGPG 115
              G  TC++     E      C C  G   G    C+   E    P   A+R  C    G
Sbjct: 2175 PCGNGTCKNVIGGFE------CTCEEGFEPGPMMTCEDINECAQNPLLCAFR--CVNTYG 2226

Query: 116  YQPVLEPPSYVV-----TLADIDECAAHEGLCAHG--TCTNTFGSFVCTCGAGWSLAPXX 168
                  P  YV+        D DEC   +  C      C N  G+++C CG G+   P  
Sbjct: 2227 SYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDG 2286

Query: 169  XX-XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
                       +P +C  G C N  GSY C C +G+ A PN  + L
Sbjct: 2287 EGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 2332



 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 69/212 (32%), Positives = 91/212 (42%), Gaps = 16/212 (7%)

Query: 6    CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCYGKVD 60
            C D +EC+  P  C +GQCI+T GS+ C C   ++   D T C D     R A   G   
Sbjct: 1847 CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCR 1906

Query: 61   LRSGTETCRDSDE--LSEDGTMAACC-CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
               G+  CR +    LS +        C+ G   GN C       +    Q C    GY+
Sbjct: 1907 NTIGSFNCRCNHGFILSHNNDCIDVDECASGN--GNLCRNGQCINTVGSFQ-CQCNEGYE 1963

Query: 118  PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
              + P     T  DI+EC      CA GTC N  GS+ C C  G+SL             
Sbjct: 1964 --VAPDGR--TCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL-QNEKCEDIDECV 2018

Query: 178  XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              P++C  G C N  GS+ CLCPEG+    +G
Sbjct: 2019 EEPEICALGTCSNTEGSFKCLCPEGFSLSSSG 2050



 Score = 87.4 bits (207), Expect = 4e-17
 Identities = 48/134 (35%), Positives = 60/134 (44%), Gaps = 12/134 (8%)

Query: 79  TMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAH 138
           T   CC +VG AWG+ C+ CP        Q  P   G+ P +   +      D+DEC A 
Sbjct: 205 TKTLCCATVGRAWGHPCEMCPA-------QPHPCRRGFIPNIRTGA----CQDVDECQAI 253

Query: 139 EGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCGPGVCRNLPGSYVC 197
            GLC  G C NT GSF C C AG  L                P +C  G C N   SY C
Sbjct: 254 PGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFC 313

Query: 198 LCPEGYVAMPNGSQ 211
            CP G+   P+G++
Sbjct: 314 KCPPGFYTSPDGTR 327



 Score = 87.4 bits (207), Expect = 4e-17
 Identities = 58/211 (27%), Positives = 83/211 (39%), Gaps = 10/211 (4%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +CTD+DEC+ +P  C  GQC N  G Y C C   +    D   C D  +      + L  
Sbjct: 1235 SCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG 1294

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGGPGYQPVLEP 122
              E  + S     D   +      G    N C+      G  A   +C    G       
Sbjct: 1295 TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHA---VCTNTAGSFKCSCS 1351

Query: 123  PSYV---VTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            P ++   +   D+DEC+    +C+ H  C NT GS+ C C  G++               
Sbjct: 1352 PGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT-GDGFTCTDLDECSE 1410

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              ++CG G C N PG Y C C  G+V   +G
Sbjct: 1411 NLNLCGNGQCLNAPGGYRCECDMGFVPSADG 1441



 Score = 87.4 bits (207), Expect = 4e-17
 Identities = 62/213 (29%), Positives = 84/213 (39%), Gaps = 22/213 (10%)

Query: 6    CTDVDECK-SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            CTD++EC+    +C ++  C NT GS+ C C P +  + DG  C D  +          +
Sbjct: 1320 CTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDGIKCTDLDECS--------N 1369

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNY-C---DPCPEPGSEAYRQLCPGGPG-YQP 118
            GT  C    +         C C  G     + C   D C E  +      C   PG Y+ 
Sbjct: 1370 GTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRC 1429

Query: 119  VLE----PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
              +    P +      DIDEC+    +C  GTC N  G F C C  G+ L          
Sbjct: 1430 ECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDV 1488

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMP 207
                 P  C  G C N PGSY+C CP  +   P
Sbjct: 1489 NECLDPTTCISGNCVNTPGSYICDCPPDFELNP 1521



 Score = 86.2 bits (204), Expect = 8e-17
 Identities = 61/208 (29%), Positives = 78/208 (37%), Gaps = 19/208 (9%)

Query: 6    CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C DV+EC  +P  C  G C NT+GS+ C C   Y      T C D  +           G
Sbjct: 1278 CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEI--------G 1329

Query: 65   TETCRDSDELSEDGTMAACCCSVG-AAWGNYC---DPCPEPGSEAYRQL--CPGGPGYQP 118
               C      +       C CS G    G  C   D C   G+    Q   C    G   
Sbjct: 1330 AHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSN-GTHMCSQHADCKNTMGSYR 1388

Query: 119  VLEPPSYV---VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             L    Y     T  D+DEC+ +  LC +G C N  G + C C  G+  +          
Sbjct: 1389 CLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDID 1448

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                P++C  G C NLPG + C C  GY
Sbjct: 1449 ECSLPNICVFGTCHNLPGLFRCECEIGY 1476



 Score = 85.4 bits (202), Expect = 1e-16
 Identities = 54/159 (33%), Positives = 72/159 (45%), Gaps = 20/159 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C D+DEC+S   C  G C N+ GS+ C C     L    T C ++ K  C+  V    G 
Sbjct: 805 CEDIDECES-SPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVI--DG- 860

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSY 125
              R    ++     + CC S+GAAWG+ C  C          +C  G GY  +      
Sbjct: 861 ---RCEININGATLKSQCCSSLGAAWGSPCTLC------QVDPIC--GKGYSRIKG---- 905

Query: 126 VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
                DIDEC    G+C +G C NT GSF C C +G +L
Sbjct: 906 -TQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTL 943



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 48/124 (38%), Positives = 61/124 (49%), Gaps = 17/124 (13%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC + P  C+ G+C NT  SY C+CPP +    DGT C D R   CY    L +G
Sbjct: 286 CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCY--TALTNG 343

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW--GNYCDP--CPEPGSEAYRQLC------PGGP 114
               R S++L +  T   CCC  G  W  G    P  CP   +E + +LC      PG P
Sbjct: 344 ----RCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRP 399

Query: 115 GYQP 118
            Y P
Sbjct: 400 EYPP 403



 Score = 83.0 bits (196), Expect = 8e-16
 Identities = 63/214 (29%), Positives = 85/214 (39%), Gaps = 26/214 (12%)

Query: 6    CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D++EC+ S   C  G+C+N  G Y C C P Y    D   C D  +        +  G
Sbjct: 1153 CIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSI-----MNGG 1207

Query: 65   TET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS-EAYRQLCPGG-----PGYQ 117
             ET C +S+   E      C C  G A       C +    E    +C GG     PG  
Sbjct: 1208 CETFCTNSEGSYE------CSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEY 1261

Query: 118  PVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS-LAPXXXXX 171
              L    ++      T  D++EC  +  +C  GTC NT GSF+C C  G+S         
Sbjct: 1262 RCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321

Query: 172  XXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYV 204
                       CG   VC N  GS+ C C  G++
Sbjct: 1322 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI 1355



 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 18/212 (8%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----C-YGKVD 60
            D++ECK  P  C +G+C NT GS+ CRC   + L S+   C D  + R     C  G+  
Sbjct: 1028 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087

Query: 61   LRSGTETCRDSDELSEDG-TMAACCCSVGAAWGN--YCDPCPEPGSE-AYRQLCPGGPGY 116
               G   C+  DE  E G  M   C  +     +   C       +E +YR  CP  PG+
Sbjct: 1088 NTPGDFECK-CDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECP--PGH 1144

Query: 117  QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
            Q  L P   +    DI+EC     LC +G C N  G + C C  G+   P          
Sbjct: 1145 Q--LSPN--ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1200

Query: 177  XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                +      C N  GSY C C  G+  MP+
Sbjct: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFALMPD 1232



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 63/222 (28%), Positives = 92/222 (41%), Gaps = 21/222 (9%)

Query: 5    NCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            N  D+DECK     C+ G+C+N +GSY C C   Y     GT+C D  +     K     
Sbjct: 2399 NGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPK----P 2454

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGGPGYQP 118
                C++++   +      C C  G      G  C    E  ++ +  + LC    G   
Sbjct: 2455 CNFICKNTEGSYQ------CSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFT 2508

Query: 119  VLEPPSYV---VTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
               PP +     +  D +EC +   LC + G C NT GSF C C  G+SL          
Sbjct: 2509 CKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDV 2568

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
                    C  G C+N+ G Y C CP+GY+     +Q + +N
Sbjct: 2569 DECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDEN 2609



 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 67/218 (30%), Positives = 94/218 (43%), Gaps = 24/218 (11%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----CY 56
            G +C D+DEC + Q +CQ+  C+NT G +TC+CPP +      T+C D+ +       C 
Sbjct: 2480 GRSCKDLDECATKQHNCQF-LCVNTIGGFTCKCPPGF--TQHHTSCIDNNECTSDINLCG 2536

Query: 57   GKVDLRS--GTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
             K   ++  G+ TC      S D T  + C  V    GN+ C    +     YR  CP  
Sbjct: 2537 SKGICQNTPGSFTCECQRGFSLDQT-GSSCEDVDECEGNHRCQHGCQNIIGGYRCSCP-- 2593

Query: 114  PGYQPVLEPPSYVVTLADIDEC-AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
             GY    +    V    D +EC +AH  +C   +C NT GS+ C C AG+          
Sbjct: 2594 QGYLQHYQWNQCV----DENECLSAH--ICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ 2647

Query: 173  XXXXXXRPDV-CGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       C  G   N  G Y+C CP GY  +  G
Sbjct: 2648 DINECGSAQAPCSYG-SSNTEGGYLCGCPPGYFRIGQG 2684



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 59/209 (28%), Positives = 86/209 (41%), Gaps = 18/209 (8%)

Query: 3    GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCY 56
            G +C D++EC ++P+ C +  C NT+GSY C CP  Y L  DG +C D     +++  C 
Sbjct: 2439 GTSCVDLNECNQAPKPCNF-ICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ 2497

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG--P 114
                   G  TC+     ++  T     C       +  + C   GS+   Q  PG    
Sbjct: 2498 FLCVNTIGGFTCKCPPGFTQHHT----SCIDNNECTSDINLC---GSKGICQNTPGSFTC 2550

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
              Q          +  D+DEC  +   C HG C N  G + C+C  G+            
Sbjct: 2551 ECQRGFSLDQTGSSCEDVDECEGNH-RCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDE 2608

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                   +CG   C N  GSY C+CP G+
Sbjct: 2609 NECLSAHICGGASCHNTLGSYKCMCPAGF 2637



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 49/166 (29%), Positives = 74/166 (44%), Gaps = 21/166 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC+    C  G+CIN QGSYTC+C   Y+     T C D  +    G++      
Sbjct: 488 CIDVDECEK-NPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRI------ 540

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG------PGYQPV 119
             C +   ++ DG+   C C+ G         C +    + R +C  G        ++ +
Sbjct: 541 --CNNGRCINTDGSF-HCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCI 597

Query: 120 LEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
            +P   + +      DI+EC    G+C +G C NT GS+ C C  G
Sbjct: 598 CKPGFQLASDGRYCKDINECET-PGICMNGRCVNTDGSYRCECFPG 642



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 56/194 (28%), Positives = 72/194 (37%), Gaps = 20/194 (10%)

Query: 18  CQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCYGKVDLRS-GTETCRDSDE 73
           CQ G+CI T GS  C C   ++L   G  C D     K  C G   + + G+ TC+    
Sbjct: 460 CQNGRCIPTPGSCRCECNKGFQLDLRG-ECIDVDECEKNPCAGGECINNQGSYTCQCRAG 518

Query: 74  LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG-YQPVLEPPSYVV----T 128
                T   C            D C + G       C    G +  V     +V      
Sbjct: 519 YQSTLTRTEC---------RDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 569

Query: 129 LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVC 188
             D+DEC+    +C +G C N  GSF C C  G+ LA              P +C  G C
Sbjct: 570 CEDMDECSI-RNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRC 628

Query: 189 RNLPGSYVCLCPEG 202
            N  GSY C C  G
Sbjct: 629 VNTDGSYRCECFPG 642



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 18/176 (10%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARC 55
            + G  C D DEC     C  G C N  G + C C   +E        D   C  +     
Sbjct: 2159 LAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCA 2218

Query: 56   YGKVDLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR----QLC 110
            +  V+     E  C     L ED  M  C        G +   C E   E        +C
Sbjct: 2219 FRCVNTYGSYECKCPVGYVLREDRRM--CKDEDECEEGKH--DCTEKQMECKNLIGTYMC 2274

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              GPGYQ   +    V    D +EC    G+C +G C NT GS+ C C  G++ +P
Sbjct: 2275 ICGPGYQRRPDGEGCV----DENECQTKPGICENGRCLNTRGSYTCECNDGFTASP 2326



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 59/213 (27%), Positives = 82/213 (38%), Gaps = 25/213 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D++EC   P+ C  G C N  GSY C CPP Y L ++   C D  +  C  + ++
Sbjct: 1968 GRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE--KCEDIDE--CVEEPEI 2023

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
                 TC +++     G+   C C  G +  +    C +           GG    P   
Sbjct: 2024 -CALGTCSNTE-----GSFK-CLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSR 2076

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTC----TNTFGSF--VCTCGAGWSLAPXXXXXXXXX 175
              S        + C A +G      C    T    +F  +C  G+G  + P         
Sbjct: 2077 NHSKQ------ECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDE 2130

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                PDVC  G C N  GSY C CP GY+   N
Sbjct: 2131 CK-EPDVCKHGQCINTDGSYRCECPFGYILAGN 2162



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/177 (30%), Positives = 71/177 (40%), Gaps = 26/177 (14%)

Query: 3    GFNCTDVDECKS-PQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G  CTD+DEC +    C Q+  C NT GSY C C   Y    DG  C D  +  C   ++
Sbjct: 1358 GIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDE--CSENLN 1413

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCPGGP 114
            L      C +   L+  G    C C +G   +A G  C   D C  P    +   C   P
Sbjct: 1414 L------CGNGQCLNAPGGY-RCECDMGFVPSADGKACEDIDECSLPNICVF-GTCHNLP 1465

Query: 115  GYQPVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
            G         Y +        D++EC      C  G C NT GS++C C   + L P
Sbjct: 1466 GLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCISGNCVNTPGSYICDCPPDFELNP 1521



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 36/119 (30%), Positives = 49/119 (41%), Gaps = 8/119 (6%)

Query: 95  CDPCPEPGSEAYRQ----LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNT 150
           C+  P  G E         C    GYQ  L          DIDEC  +  +C +G C NT
Sbjct: 494 CEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTE----CRDIDECLQNGRICNNGRCINT 549

Query: 151 FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            GSF C C AG+ +                ++C  G+C N  GS+ C+C  G+    +G
Sbjct: 550 DGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDG 608



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 47/162 (29%), Positives = 71/162 (43%), Gaps = 14/162 (8%)

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-GNYC---DPCPEPGSEAYRQLCPGG-PGYQPVL 120
            + C+    ++ DG+   C C  G    GN C   D C   G+      C     G++   
Sbjct: 2135 DVCKHGQCINTDGSYR-CECPFGYILAGNECVDTDEC-SVGNPCGNGTCKNVIGGFECTC 2192

Query: 121  EP---PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX- 176
            E    P  ++T  DI+ECA +  LCA   C NT+GS+ C C  G+ L             
Sbjct: 2193 EEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDEC 2251

Query: 177  -XXRPDVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
               + D     + C+NL G+Y+C+C  GY   P+G   + +N
Sbjct: 2252 EEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDEN 2293



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 24/47 (51%), Positives = 29/47 (61%), Gaps = 2/47 (4%)

Query: 5    NCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
            +C DVDEC S     C+ GQCINT GS+ C+C   YE+  DG  C D
Sbjct: 1927 DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVD 1973



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 22/45 (48%), Positives = 28/45 (62%), Gaps = 1/45 (2%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           C DVDEC++ P  CQ G CINT GS+ C+CP  ++L      C D
Sbjct: 244 CQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCED 288



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 55/208 (26%), Positives = 69/208 (33%), Gaps = 18/208 (8%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCY-G 57
            G  C D+DEC  P  C +G C N  G + C C   YEL   G  C D  +      C  G
Sbjct: 1441 GKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISG 1500

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
                  G+  C    +   + T   C   V    GN C     P  +     C    G  
Sbjct: 1501 NCVNTPGSYICDCPPDFELNPTRVGC---VDTRSGN-CYLDIRPRGDNGDTACSNEIGVG 1556

Query: 118  PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFG-SFVCTCGAGWSLAPXXXXXXXXXX 176
              +   S   +L       A    C      NT     +C  G G+   P          
Sbjct: 1557 --VSKASCCCSLG-----KAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDE 1609

Query: 177  XXR-PDVCGPGVCRNLPGSYVCLCPEGY 203
                P +C  G C N  GS+ C CP GY
Sbjct: 1610 CQELPGLCQGGKCINTFGSFQCRCPTGY 1637



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           D+DEC  +   CA G C N  GS+ C C AG+ S                  +C  G C 
Sbjct: 490 DVDECEKNP--CAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCI 547

Query: 190 NLPGSYVCLCPEGYVAMPNG 209
           N  GS+ C+C  G+    +G
Sbjct: 548 NTDGSFHCVCNAGFHVTRDG 567



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 8/57 (14%)

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
           CP G  Y+P L+      T  DIDEC +    C +G C N+ GSF+C C +  +L P
Sbjct: 792 CPKGFIYKPDLK------TCEDIDECESSP--CINGVCKNSPGSFICECSSESTLDP 840


>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
          Length = 2911

 Score =  195 bits (476), Expect = 9e-50
 Identities = 90/209 (43%), Positives = 115/209 (55%), Gaps = 8/209 (3%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G NCTD+DEC  P +C  G C+NT G Y C CPP+++L   G  C D+R   CY K   R
Sbjct: 1526 GGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPR 1585

Query: 63   -SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
              G+ +C  + E+    + ++CCCS+G AWGN C+ CP   S  Y  LCPGG G++P   
Sbjct: 1586 GDGSLSC--NTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRP--N 1641

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRP 180
            P    + L DIDEC    GLC  G C NTFGSF C C  G+ L+               P
Sbjct: 1642 P--ITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHP 1699

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
             VCGPG C N  G+Y C+CP  Y+ +  G
Sbjct: 1700 GVCGPGTCYNTLGNYTCICPPEYMQVNGG 1728



 Score =  168 bits (408), Expect = 2e-41
 Identities = 81/203 (39%), Positives = 108/203 (53%), Gaps = 8/203 (3%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C DV+EC+  P  C  G+C+N++GS+ C CP    L   G  C D R  +CY K D 
Sbjct: 949  GVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWD- 1007

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
                + C     +     M ACCC+VGAAWG  C+ CP+PG++ Y  LCP G G+    +
Sbjct: 1008 ---EDEC--IHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGD 1062

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
              +      DI+EC A  G+C +G C NT GSF C C +G++L                P
Sbjct: 1063 VLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISP 1122

Query: 181  DVCGPGVCRNLPGSYVCLCPEGY 203
            D+CG G+C N PGS+ C C EGY
Sbjct: 1123 DLCGSGICVNTPGSFECECFEGY 1145



 Score =  153 bits (370), Expect = 7e-37
 Identities = 76/209 (36%), Positives = 104/209 (49%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D +EC++ P  C+ G+C+N  GSY C C   ++  S GT C D+R+  C+ +V L
Sbjct: 2332 GEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEV-L 2390

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++  +    S  L    T + CCC  G  WG+ C+ CP PG+  Y+++CP GPG      
Sbjct: 2391 QTICQMASSSRNLV---TKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPG------ 2441

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               Y     DIDEC     LC +G C NT GSF C C  G++                 P
Sbjct: 2442 ---YTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSP 2498

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GSY C CP GYV   +G
Sbjct: 2499 KPCN-YICKNTEGSYQCSCPRGYVLQEDG 2526



 Score =  147 bits (356), Expect = 3e-35
 Identities = 73/206 (35%), Positives = 105/206 (50%), Gaps = 14/206 (6%)

Query: 5    NCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NC D++EC + P  C +G C NT G + C CPP + L  +G  C+D+R++ C+      +
Sbjct: 2052 NCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCF------T 2105

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
              E  + S   + + T A CCCS   G  WG+ C+ CP+    A++ LCP G G  P L 
Sbjct: 2106 NFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLH 2165

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
                  T  D++EC    G+C++G C NT GSF C C  G++L                +
Sbjct: 2166 D-----TREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGN 2220

Query: 182  VCGPGVCRNLPGSYVCLCPEGYVAMP 207
             CG G C N+ GS+ C C EG+   P
Sbjct: 2221 PCGNGTCTNVIGSFECNCNEGFEPGP 2246



 Score =  144 bits (349), Expect = 2e-34
 Identities = 82/210 (39%), Positives = 104/210 (49%), Gaps = 15/210 (7%)

Query: 6    CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC + P  C  G C NT G+YTC CPP Y  V+ G  C D RK+ CY      +G
Sbjct: 1689 CEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSY---NG 1745

Query: 65   TETCRDSDELSEDGTMAACCC--SVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
            T TC   +EL  + T   CCC  +VG A    C+PCP PG+  ++ +C   PG+   +  
Sbjct: 1746 T-TC--ENELPFNVTKRMCCCTYNVGKAGNKPCEPCPTPGTADFKTICGNIPGFTFDIHT 1802

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD- 181
               V    DIDEC    G+CA+G C N  GSF C C  G+S                 D 
Sbjct: 1803 GKAV----DIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDN 1858

Query: 182  VCGPGV-CRNLPGSYVCLCPEGYVAMPNGS 210
            +C     C N PGSY C C  G+   PNG+
Sbjct: 1859 LCQRNADCINSPGSYRCECAAGFKLSPNGA 1888



 Score =  137 bits (331), Expect = 3e-32
 Identities = 73/204 (35%), Positives = 95/204 (46%), Gaps = 16/204 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  CTDVDEC++P  C  G CIN++GS+ C CPP   +  DG  C D+  ++ CYG +  
Sbjct: 652 GRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKK 711

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
                    +   SE      CC +    +G  C PCP   S  +  LC  G G      
Sbjct: 712 GVCVRPFPGAVTKSE-----CCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVG------ 760

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                V   DI+ECA    +CA+G C N  GS+ C C +G+   A               
Sbjct: 761 ---ITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNR 817

Query: 181 DVCGPGVCRNLPGSYVCLCPEGYV 204
            +C  G+CRN PGSY C CP GYV
Sbjct: 818 LLCDNGLCRNTPGSYSCTCPPGYV 841



 Score = 98.7 bits (235), Expect = 1e-20
 Identities = 71/212 (33%), Positives = 99/212 (46%), Gaps = 26/212 (12%)

Query: 6    CTDVDECKSPQS-CQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----C-YG 57
            C D+DEC +  + CQ    CIN+ GSY C C   ++L  +G AC D  +       C +G
Sbjct: 1847 CEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHG 1905

Query: 58   K-VDLRSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYCD--PCPEPGSEAYRQLCPGG 113
              VDL+   +  C +  + S+D TM   C  V     + C    C      +Y  LC   
Sbjct: 1906 LCVDLQGSYQCICHNGFKASQDQTM---CMDVDECERHPCGNGTCKNTVG-SYNCLCY-- 1959

Query: 114  PGYQPVLEPPSYVVTLADIDECAAHEG-LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
            PG++      ++     DIDEC++  G +C +G C N  GSF C C  G+ L P      
Sbjct: 1960 PGFEL-----THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCI 2014

Query: 173  XXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                    P  C PG C+NL GS+ C+CP GY
Sbjct: 2015 DTNECVALPGSCSPGTCQNLEGSFRCICPPGY 2046



 Score = 97.1 bits (231), Expect = 5e-20
 Identities = 67/214 (31%), Positives = 91/214 (42%), Gaps = 22/214 (10%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  G C+NT GS+ C C   YE      + +   K  C        
Sbjct: 1111 NCTDIDECRISPDLCGSGICVNTPGSFECECFEGYE------SGFMMMK-NCMDIDGCER 1163

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQ-LCPGGP-----GYQ 117
                CR    ++ +G+   C C +G       + C +    +    LC  G      G  
Sbjct: 1164 NPLLCRGGTCVNTEGSFQ-CDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTY 1222

Query: 118  PVLEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                 P Y  T       DIDEC    G C    CTN+ GS+ C+C  G++L P      
Sbjct: 1223 QCSCNPGYQATPDRQGCTDIDECMIMNGGC-DTQCTNSEGSYECSCSEGYALMPDGRSCA 1281

Query: 173  XXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                    PD+C  G C N+PG Y CLC +G++A
Sbjct: 1282 DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMA 1315



 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 69/225 (30%), Positives = 92/225 (40%), Gaps = 28/225 (12%)

Query: 1   MPGFNCTDVDECKSPQSCQYGQCINTQGSYTCR--CPPNYELVSDGTAC-YDSRKARCYG 57
           M G  C D D C+    CQ G      G   C   C      ++   AC Y     +C  
Sbjct: 154 MNGGTCAD-DHCQ----CQKGYIGTYCGQPVCENGCQNGGRCIAQPCACVYGFTGPQC-- 206

Query: 58  KVDLRSGTETCRDSDELSEDG------TMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCP 111
           + D R+G    + ++++ +        T   CC + G AWG+ C+ CP     A  Q C 
Sbjct: 207 ERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATTGRAWGHPCEMCP-----AQPQPCR 261

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX- 170
            G        P        D+DEC A  G+C  G C NT GSF C C AG   +      
Sbjct: 262 RG------FIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKC 315

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQ 215
                    P +C  G C N  GSY C+CP GYV   +GS+ + Q
Sbjct: 316 EDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQ 360



 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 52/159 (32%), Positives = 73/159 (45%), Gaps = 20/159 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C D++EC+S   C  G C N  GS+ C C P  +L S G  C DS K  C+  +      
Sbjct: 849 CEDINECES-NPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNI------ 901

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSY 125
           +  R    ++     + CC ++GAAWG+ C+ C           CP G            
Sbjct: 902 QDSRCEVNINGATLKSECCATLGAAWGSPCERC------ELDTACPRGLA-------RIK 948

Query: 126 VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
            VT  D++EC    G+C +G C N+ GSF C C  G +L
Sbjct: 949 GVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTL 987



 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 57/207 (27%), Positives = 84/207 (40%), Gaps = 17/207 (8%)

Query: 6    CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C DV+EC  +   C +G+C NT+GS+ C C   Y +    T C D  +           G
Sbjct: 1322 CIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEI--------G 1373

Query: 65   TETC-RDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSE-AYRQLCPGGPGYQPV 119
               C   +  L+  G+    C       G  C   D C     + +    C   PG    
Sbjct: 1374 AHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRC 1433

Query: 120  LEPPSYV---VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
                 +     T +D+DECA +  LC +G C N  G++ C C  G++ A           
Sbjct: 1434 ACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDE 1493

Query: 177  XXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                ++C  G C NLPG + C+C +GY
Sbjct: 1494 CSFQNICVSGTCNNLPGMFHCICDDGY 1520



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 67/221 (30%), Positives = 93/221 (42%), Gaps = 26/221 (11%)

Query: 2    PGFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            P   C D +EC + P  C +G C++ QGSY C C   ++   D T C D  +   +    
Sbjct: 1885 PNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHP--- 1941

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVG--AAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
               G  TC+++      G+   C C  G      N C    E  S  + Q+C  G  +  
Sbjct: 1942 --CGNGTCKNTV-----GSYN-CLCYPGFELTHNNDCLDIDECSS-FFGQVCRNGRCFNE 1992

Query: 119  V-----LEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXX 168
            +     L    Y +T       D +EC A  G C+ GTC N  GSF C C  G+ +    
Sbjct: 1993 IGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN 2052

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       P++C  G C N PG + CLCP G+V   NG
Sbjct: 2053 CIDINECDED-PNICLFGSCTNTPGGFQCLCPPGFVLSDNG 2092



 Score = 90.2 bits (214), Expect = 5e-18
 Identities = 46/111 (41%), Positives = 55/111 (49%), Gaps = 9/111 (8%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC   P  C+ G+C NT GSY C CP  Y   +DG+ C D R   C+      SG
Sbjct: 315 CEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCF------SG 368

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQLCPGG 113
               R + EL    T   CCC  G  W  G   + CP  GSE YR+LC  G
Sbjct: 369 LVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDG 419



 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 61/212 (28%), Positives = 86/212 (40%), Gaps = 16/212 (7%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----CYGKVDL 61
            D++ECK+ P  C YG+C NT GS+ CRC   + L  +   C D  + R     C   + +
Sbjct: 1072 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 1131

Query: 62   RS-GTETCRDSDELSEDGTMAACCCSVGAAWGN--YCDPCPEPGSEAYRQL-CPGGPGYQ 117
             + G+  C   +       M   C  +     N   C       +E   Q  CP G    
Sbjct: 1132 NTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELS 1191

Query: 118  PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
            P  E         DI+EC+  + LC +G C N  G++ C+C  G+   P           
Sbjct: 1192 PSRED------CVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDEC 1245

Query: 178  XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
               +      C N  GSY C C EGY  MP+G
Sbjct: 1246 MIMNGGCDTQCTNSEGSYECSCSEGYALMPDG 1277



 Score = 87.8 bits (208), Expect = 3e-17
 Identities = 64/217 (29%), Positives = 91/217 (41%), Gaps = 30/217 (13%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D++EC  S   C+ G+C+N  G+Y C C P Y+   D   C D  +        +  
Sbjct: 1196 DCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMI-----MNG 1250

Query: 64   GTET-CRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLCPGG-----P 114
            G +T C +S+   E      C CS G A    G  C    E   E    +C GG     P
Sbjct: 1251 GCDTQCTNSEGSYE------CSCSEGYALMPDGRSCADIDE--CENNPDICDGGQCTNIP 1302

Query: 115  GYQPVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX 169
            G    L    ++      T  D++EC  +  +C  G C NT GSF+C C  G+S+     
Sbjct: 1303 GEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTT 1362

Query: 170  X-XXXXXXXXRPDVCG-PGVCRNLPGSYVCLCPEGYV 204
                          C     C N+PGS+ C C EG++
Sbjct: 1363 GCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWI 1399



 Score = 86.6 bits (205), Expect = 6e-17
 Identities = 65/210 (30%), Positives = 86/210 (40%), Gaps = 20/210 (9%)

Query: 3    GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCY 56
            G +C D+DEC +SP+ C Y  C NT+GSY C CP  Y L  DG  C D     +++  C 
Sbjct: 2485 GTSCIDLDECSQSPKPCNY-ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQ 2543

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-EPGSEAYRQLCPGGPG 115
                   G  TC+     ++  T  AC  +      N C   P   G +   Q  PG   
Sbjct: 2544 FLCVNTLGGFTCKCPPGFTQHHT--ACIDN------NECGSQPLLCGGKGICQNTPGSFS 2595

Query: 116  --YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
               Q      +  +   D+DEC  +   C HG C N  G + C C  G+           
Sbjct: 2596 CECQRGFSLDATGLNCEDVDECDGNH-RCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVD 2653

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P+ CG   C N  GSY C CP G+
Sbjct: 2654 ENECSNPNACGSASCYNTLGSYKCACPSGF 2683



 Score = 86.6 bits (205), Expect = 6e-17
 Identities = 68/217 (31%), Positives = 95/217 (43%), Gaps = 22/217 (10%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCY 56
            G  C D+DEC++ Q +CQ+  C+NT G +TC+CPP +      TAC D     S+   C 
Sbjct: 2526 GKTCKDLDECQTKQHNCQF-LCVNTLGGFTCKCPPGF--TQHHTACIDNNECGSQPLLCG 2582

Query: 57   GKVDLRS--GTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
            GK   ++  G+ +C      S D T    C  V    GN+ C    +     YR  CP  
Sbjct: 2583 GKGICQNTPGSFSCECQRGFSLDAT-GLNCEDVDECDGNHRCQHGCQNILGGYRCGCP-- 2639

Query: 114  PGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XX 172
             GY    +    V    D +EC ++   C   +C NT GS+ C C +G+S          
Sbjct: 2640 QGYIQHYQWNQCV----DENEC-SNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHD 2694

Query: 173  XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                    + C  G C N  G Y+C CP GY  +  G
Sbjct: 2695 VNECSSSKNPCNYG-CSNTEGGYLCGCPPGYYRVGQG 2730



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 69/222 (31%), Positives = 93/222 (41%), Gaps = 24/222 (10%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
            D+DECK  P  C  G CIN  GS+ C CP  +         Y+     C    +  +G  
Sbjct: 1807 DIDECKEIPGICANGVCINQIGSFRCECPTGFS--------YNDLLLVCEDIDECSNGDN 1858

Query: 67   TC-RDSDELSEDGTMAACCCSVG--AAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQPV 119
             C R++D ++  G+   C C+ G   +    C   + C E  +     LC    G YQ +
Sbjct: 1859 LCQRNADCINSPGSYR-CECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCI 1917

Query: 120  LE---PPSYVVTLA-DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                   S   T+  D+DEC  H   C +GTC NT GS+ C C  G+ L           
Sbjct: 1918 CHNGFKASQDQTMCMDVDECERHP--CGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDE 1975

Query: 176  -XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
                   VC  G C N  GS+ CLC EGY   P+G   +  N
Sbjct: 1976 CSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTN 2017



 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 66/220 (30%), Positives = 90/220 (40%), Gaps = 25/220 (11%)

Query: 8    DVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
            DV+EC +SP  C  GQCINT GS+ C CP  Y L   G  C D+ +      +    G  
Sbjct: 2170 DVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDEC----SIGNPCGNG 2225

Query: 67   TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL-----CPGGPGYQPVLE 121
            TC +     E      C C+ G   G   + C +    A   L     C    G      
Sbjct: 2226 TCTNVIGSFE------CNCNEGFEPGPMMN-CEDINECAQNPLLCALRCMNTFGSYECTC 2278

Query: 122  PPSYVVT-----LADIDECAA--HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
            P  Y +        D+DECA   H+       C N  G+F+C C  G +  P        
Sbjct: 2279 PIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDE 2338

Query: 175  XX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
                 +P +C  G C N+ GSY C C EG+ +  +G++ L
Sbjct: 2339 NECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECL 2378



 Score = 83.0 bits (196), Expect = 8e-16
 Identities = 68/231 (29%), Positives = 94/231 (40%), Gaps = 23/231 (9%)

Query: 2    PGFNCT--DVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
            PG+     D+DECK  P  C  GQCINT GS+ C C   Y     GT+C D  +     K
Sbjct: 2440 PGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPK 2499

Query: 59   VDLRSGTETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGG 113
                     C++++   +      C C  G      G  C    E  ++ +  + LC   
Sbjct: 2500 ----PCNYICKNTEGSYQ------CSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNT 2549

Query: 114  PGYQPVLEPPSYV---VTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXX 169
             G      PP +        D +EC +   LC   G C NT GSF C C  G+SL     
Sbjct: 2550 LGGFTCKCPPGFTQHHTACIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGL 2609

Query: 170  XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQNLSTN 220
                         C  G C+N+ G Y C CP+GY+     +Q + +N  +N
Sbjct: 2610 NCEDVDECDGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSN 2659



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 64/209 (30%), Positives = 81/209 (38%), Gaps = 45/209 (21%)

Query: 3    GFNCTDVDECKS-PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G  C D+DEC +    C    QC+NT GSY C C   +    DG  C D           
Sbjct: 1402 GIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF--TGDGFTCSD----------- 1448

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
                 + C ++  L E+G     C +V             PG  AYR  C    G+ P  
Sbjct: 1449 ----VDECAENINLCENGQ----CLNV-------------PG--AYR--CECEMGFTPAS 1483

Query: 121  EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
            +  S      DIDEC + + +C  GTC N  G F C C  G+ L               P
Sbjct: 1484 DSRS----CQDIDEC-SFQNICVSGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADP 1538

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C  G+C N PG Y C CP  +   P G
Sbjct: 1539 INCVNGLCVNTPGRYECNCPPDFQLNPTG 1567



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 50/168 (29%), Positives = 74/168 (44%), Gaps = 23/168 (13%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           +C DVDEC S   C  G C+NT GSY C+C   ++      AC D  +        +++G
Sbjct: 531 DCIDVDECTS-NPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDEC-------IQNG 582

Query: 65  TETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCPGGPGYQP 118
              C++   ++ DG+   C C+ G      G  C   D C    +     +C    G   
Sbjct: 583 V-LCKNGRCVNSDGSF-QCICNAGFELTTDGKNCVDHDECTTT-NMCLNGMCINEDGSFK 639

Query: 119 VLEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
            +  P +V+        D+DEC    G+C +G C N+ GSF C C  G
Sbjct: 640 CICKPGFVLAPNGRYCTDVDECQT-PGICMNGHCINSEGSFRCDCPPG 686



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 31/79 (39%), Positives = 41/79 (51%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           DIDEC  +  LC +G C N+ GSF C C AG+ L                ++C  G+C N
Sbjct: 574 DIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCIN 633

Query: 191 LPGSYVCLCPEGYVAMPNG 209
             GS+ C+C  G+V  PNG
Sbjct: 634 EDGSFKCICKPGFVLAPNG 652



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 61/213 (28%), Positives = 82/213 (38%), Gaps = 25/213 (11%)

Query: 9   VDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           +D CK   + C  G+CI T  SY C C   Y+  ++G  C D         VD    +  
Sbjct: 494 IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD-CID---------VD-ECTSNP 542

Query: 68  CRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQPVL 120
           C + D ++  G+   C C  G         C   D C + G       C    G +Q + 
Sbjct: 543 CTNGDCVNTPGSY-YCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCIC 601

Query: 121 EPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
                + T      D DEC     +C +G C N  GSF C C  G+ LAP          
Sbjct: 602 NAGFELTTDGKNCVDHDECTT-TNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDE 660

Query: 177 XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              P +C  G C N  GS+ C CP G     +G
Sbjct: 661 CQTPGICMNGHCINSEGSFRCDCPPGLAVGMDG 693



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 4/97 (4%)

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP-- 180
            P  ++   DI+ECA +  LCA   C NTFGS+ CTC  G++L                  
Sbjct: 2244 PGPMMNCEDINECAQNPLLCAL-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLH 2302

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
            D    G+ C+NL G+++C+CP G    P+G   + +N
Sbjct: 2303 DCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDEN 2339



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 58/222 (26%), Positives = 79/222 (35%), Gaps = 21/222 (9%)

Query: 3    GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            GF C+DVDEC ++   C+ GQC+N  G+Y C C   +   SD  +C D  +  C  +   
Sbjct: 1443 GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDE--CSFQNIC 1500

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCPGGPG 115
             SG  TC +         M  C C  G      G  C   D C +P       LC   PG
Sbjct: 1501 VSG--TCNNLP------GMFHCICDDGYELDRTGGNCTDIDECADP-INCVNGLCVNTPG 1551

Query: 116  YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                  PP + +    +       G C         GS  C    G  ++          
Sbjct: 1552 RYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGK 1611

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQNL 217
                P    P V       Y  LCP G    PN    +L+++
Sbjct: 1612 AWGNPCETCPPVNST---EYYTLCPGGEGFRPNPITIILEDI 1650



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 29/82 (35%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
           EP +      DIDEC  +  LC +G C NT GS+ CTC  G+                  
Sbjct: 799 EPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFR-TETETCEDINECES 857

Query: 181 DVCGPGVCRNLPGSYVCLCPEG 202
           + C  G CRN  GS+ C C  G
Sbjct: 858 NPCVNGACRNNLGSFNCECSPG 879



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 48/179 (26%), Positives = 63/179 (35%), Gaps = 36/179 (20%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTAC---------- 47
            G  C D DEC     C  G C N  GS+ C C   +E        D   C          
Sbjct: 2207 GVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCALR 2266

Query: 48   ----YDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS 103
                + S +  C     LR   + C+D DE +E       C S G    N          
Sbjct: 2267 CMNTFGSYECTCPIGYALREDQKMCKDLDECAEG---LHDCESRGMMCKNLIG------- 2316

Query: 104  EAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGW 162
              +  +CP G   +P  E         D +EC    G+C +G C N  GS+ C C  G+
Sbjct: 2317 -TFMCICPPGMARRPDGE------GCVDENECRTKPGICENGRCVNIIGSYRCECNEGF 2368



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 4/96 (4%)

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXX 171
           G  G  P++      +    ID C  H  LC +G C  T  S+ C C  G+         
Sbjct: 476 GAGGQGPIIT--GLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCI 533

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMP 207
                   P  C  G C N PGSY C C  G+   P
Sbjct: 534 DVDECTSNP--CTNGDCVNTPGSYYCKCHAGFQRTP 567



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 2    PGFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
            P  NC D++EC ++P  C   +C+NT GSY C CP  Y L  D   C D
Sbjct: 2246 PMMNCEDINECAQNPLLCAL-RCMNTFGSYECTCPIGYALREDQKMCKD 2293



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 24/62 (38%), Positives = 29/62 (46%), Gaps = 7/62 (11%)

Query: 109 LCPGGPGYQPVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS 163
           LC   PG      PP YV      T  DI+EC ++   C +G C N  GSF C C  G  
Sbjct: 824 LCRNTPGSYSCTCPPGYVFRTETETCEDINECESNP--CVNGACRNNLGSFNCECSPGSK 881

Query: 164 LA 165
           L+
Sbjct: 882 LS 883


>AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital
           contractural arachnodactyly) variant protein.
          Length = 1976

 Score =  195 bits (476), Expect = 9e-50
 Identities = 90/209 (43%), Positives = 115/209 (55%), Gaps = 8/209 (3%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NCTD+DEC  P +C  G C+NT G Y C CPP+++L   G  C D+R   CY K   R
Sbjct: 591 GGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPR 650

Query: 63  -SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
             G+ +C  + E+    + ++CCCS+G AWGN C+ CP   S  Y  LCPGG G++P   
Sbjct: 651 GDGSLSC--NTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRP--N 706

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRP 180
           P    + L DIDEC    GLC  G C NTFGSF C C  G+ L+               P
Sbjct: 707 P--ITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHP 764

Query: 181 DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            VCGPG C N  G+Y C+CP  Y+ +  G
Sbjct: 765 GVCGPGTCYNTLGNYTCICPPEYMQVNGG 793



 Score =  168 bits (408), Expect = 2e-41
 Identities = 81/203 (39%), Positives = 108/203 (53%), Gaps = 8/203 (3%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C DV+EC+  P  C  G+C+N++GS+ C CP    L   G  C D R  +CY K D 
Sbjct: 14  GVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWD- 72

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
               + C     +     M ACCC+VGAAWG  C+ CP+PG++ Y  LCP G G+    +
Sbjct: 73  ---EDEC--IHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGD 127

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
             +      DI+EC A  G+C +G C NT GSF C C +G++L                P
Sbjct: 128 VLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISP 187

Query: 181 DVCGPGVCRNLPGSYVCLCPEGY 203
           D+CG G+C N PGS+ C C EGY
Sbjct: 188 DLCGSGICVNTPGSFECECFEGY 210



 Score =  153 bits (370), Expect = 7e-37
 Identities = 76/209 (36%), Positives = 104/209 (49%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D +EC++ P  C+ G+C+N  GSY C C   ++  S GT C D+R+  C+ +V L
Sbjct: 1397 GEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEV-L 1455

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++  +    S  L    T + CCC  G  WG+ C+ CP PG+  Y+++CP GPG      
Sbjct: 1456 QTICQMASSSRNLV---TKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPG------ 1506

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               Y     DIDEC     LC +G C NT GSF C C  G++                 P
Sbjct: 1507 ---YTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSP 1563

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GSY C CP GYV   +G
Sbjct: 1564 KPCN-YICKNTEGSYQCSCPRGYVLQEDG 1591



 Score =  149 bits (362), Expect = 6e-36
 Identities = 83/210 (39%), Positives = 105/210 (50%), Gaps = 15/210 (7%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC + P  C  G C NT G+YTC CPP Y  V+ G  C D RK+ CY      +G
Sbjct: 754 CEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSY---NG 810

Query: 65  TETCRDSDELSEDGTMAACCC--SVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
           T TC   +EL  + T   CCC  +VG AW   C+PCP PG+  ++ +C   PG+   +  
Sbjct: 811 T-TC--ENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHT 867

Query: 123 PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD- 181
              V    DIDEC    G+CA+G C N  GSF C C  G+S                 D 
Sbjct: 868 GKAV----DIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDN 923

Query: 182 VCGPGV-CRNLPGSYVCLCPEGYVAMPNGS 210
           +C     C N PGSY C C  G+   PNG+
Sbjct: 924 LCQRNADCINSPGSYRCECAAGFKLSPNGA 953



 Score =  147 bits (356), Expect = 3e-35
 Identities = 73/206 (35%), Positives = 105/206 (50%), Gaps = 14/206 (6%)

Query: 5    NCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NC D++EC + P  C +G C NT G + C CPP + L  +G  C+D+R++ C+      +
Sbjct: 1117 NCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCF------T 1170

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
              E  + S   + + T A CCCS   G  WG+ C+ CP+    A++ LCP G G  P L 
Sbjct: 1171 NFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLH 1230

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
                  T  D++EC    G+C++G C NT GSF C C  G++L                +
Sbjct: 1231 D-----TREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGN 1285

Query: 182  VCGPGVCRNLPGSYVCLCPEGYVAMP 207
             CG G C N+ GS+ C C EG+   P
Sbjct: 1286 PCGNGTCTNVIGSFECNCNEGFEPGP 1311



 Score = 98.7 bits (235), Expect = 1e-20
 Identities = 71/212 (33%), Positives = 99/212 (46%), Gaps = 26/212 (12%)

Query: 6    CTDVDECKSPQS-CQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----C-YG 57
            C D+DEC +  + CQ    CIN+ GSY C C   ++L  +G AC D  +       C +G
Sbjct: 912  CEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHG 970

Query: 58   K-VDLRSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYCD--PCPEPGSEAYRQLCPGG 113
              VDL+   +  C +  + S+D TM   C  V     + C    C      +Y  LC   
Sbjct: 971  LCVDLQGSYQCICHNGFKASQDQTM---CMDVDECERHPCGNGTCKNTVG-SYNCLCY-- 1024

Query: 114  PGYQPVLEPPSYVVTLADIDECAAHEG-LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
            PG++      ++     DIDEC++  G +C +G C N  GSF C C  G+ L P      
Sbjct: 1025 PGFEL-----THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCI 1079

Query: 173  XXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                    P  C PG C+NL GS+ C+CP GY
Sbjct: 1080 DTNECVALPGSCSPGTCQNLEGSFRCICPPGY 1111



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 67/214 (31%), Positives = 92/214 (42%), Gaps = 22/214 (10%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           NCTD+DEC+ SP  C  G C+NT GS+ C C   YE      + +   K  C    +   
Sbjct: 176 NCTDIDECRISPDLCGSGICVNTPGSFECECFEGYE------SGFMMMK-NCMDIDECER 228

Query: 64  GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQ-LCPGGP-----GYQ 117
               CR    ++ +G+   C C +G       + C +    +    LC  G      G  
Sbjct: 229 NPLLCRGGTCVNTEGSFQ-CDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTY 287

Query: 118 PVLEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                P Y  T       DIDEC    G C    CTN+ GS+ C+C  G++L P      
Sbjct: 288 QCSCNPGYQATPDRQGCTDIDECMIMNGGC-DTQCTNSEGSYECSCSEGYALMPDGRSCA 346

Query: 173 XXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                   PD+C  G C N+PG Y CLC +G++A
Sbjct: 347 DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMA 380



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 67/221 (30%), Positives = 93/221 (42%), Gaps = 26/221 (11%)

Query: 2    PGFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            P   C D +EC + P  C +G C++ QGSY C C   ++   D T C D  +   +    
Sbjct: 950  PNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHP--- 1006

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVG--AAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
               G  TC+++      G+   C C  G      N C    E  S  + Q+C  G  +  
Sbjct: 1007 --CGNGTCKNTV-----GSYN-CLCYPGFELTHNNDCLDIDECSS-FFGQVCRNGRCFNE 1057

Query: 119  V-----LEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXX 168
            +     L    Y +T       D +EC A  G C+ GTC N  GSF C C  G+ +    
Sbjct: 1058 IGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN 1117

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       P++C  G C N PG + CLCP G+V   NG
Sbjct: 1118 CIDINECDED-PNICLFGSCTNTPGGFQCLCPPGFVLSDNG 1157



 Score = 89.8 bits (213), Expect = 7e-18
 Identities = 57/207 (27%), Positives = 84/207 (40%), Gaps = 17/207 (8%)

Query: 6   CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DV+EC  +   C +G+C NT+GS+ C C   Y +    T C D  +           G
Sbjct: 387 CIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEI--------G 438

Query: 65  TETC-RDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSE-AYRQLCPGGPGYQPV 119
              C   +  L+  G+    C       G  C   D C     + +    C   PG    
Sbjct: 439 AHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRC 498

Query: 120 LEPPSYV---VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
                +     T +D+DECA +  LC +G C N  G++ C C  G++ A           
Sbjct: 499 ACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDE 558

Query: 177 XXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               ++C  G C NLPG + C+C +GY
Sbjct: 559 CSFQNICVFGTCNNLPGMFHCICDDGY 585



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 61/212 (28%), Positives = 86/212 (40%), Gaps = 16/212 (7%)

Query: 8   DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----CYGKVDL 61
           D++ECK+ P  C YG+C NT GS+ CRC   + L  +   C D  + R     C   + +
Sbjct: 137 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 196

Query: 62  RS-GTETCRDSDELSEDGTMAACCCSVGAAWGN--YCDPCPEPGSEAYRQL-CPGGPGYQ 117
            + G+  C   +       M   C  +     N   C       +E   Q  CP G    
Sbjct: 197 NTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELS 256

Query: 118 PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
           P  E         DI+EC+  + LC +G C N  G++ C+C  G+   P           
Sbjct: 257 PSRED------CVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDEC 310

Query: 178 XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              +      C N  GSY C C EGY  MP+G
Sbjct: 311 MIMNGGCDTQCTNSEGSYECSCSEGYALMPDG 342



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 65/210 (30%), Positives = 87/210 (41%), Gaps = 20/210 (9%)

Query: 3    GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCY 56
            G +C D+DEC +SP+ C Y  C NT+GSY C CP  Y L  DG  C D     +++  C 
Sbjct: 1550 GTSCIDLDECSQSPKPCNY-ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQ 1608

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE-PGSEAYRQLCPGGPG 115
                   G  TC+     ++  T  AC  +      N C   P   G++   Q  PG   
Sbjct: 1609 FLCVNTLGGFTCKCPPGFTQHHT--ACIDN------NECGSQPSLCGAKGICQNTPGSFS 1660

Query: 116  --YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
               Q      +  +   D+DEC  +   C HG C N  G + C C  G+           
Sbjct: 1661 CECQRGFSLDATGLNCEDVDECDGNH-RCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVD 1718

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P+ CG   C N  GSY C CP G+
Sbjct: 1719 ENECSNPNACGSASCYNTLGSYKCACPSGF 1748



 Score = 87.8 bits (208), Expect = 3e-17
 Identities = 64/217 (29%), Positives = 91/217 (41%), Gaps = 30/217 (13%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           +C D++EC  S   C+ G+C+N  G+Y C C P Y+   D   C D  +        +  
Sbjct: 261 DCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMI-----MNG 315

Query: 64  GTET-CRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLCPGG-----P 114
           G +T C +S+   E      C CS G A    G  C    E   E    +C GG     P
Sbjct: 316 GCDTQCTNSEGSYE------CSCSEGYALMPDGRSCADIDE--CENNPDICDGGQCTNIP 367

Query: 115 GYQPVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX 169
           G    L    ++      T  D++EC  +  +C  G C NT GSF+C C  G+S+     
Sbjct: 368 GEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTT 427

Query: 170 X-XXXXXXXXRPDVCG-PGVCRNLPGSYVCLCPEGYV 204
                         C     C N+PGS+ C C EG++
Sbjct: 428 GCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWI 464



 Score = 86.2 bits (204), Expect = 8e-17
 Identities = 69/231 (29%), Positives = 95/231 (41%), Gaps = 23/231 (9%)

Query: 2    PGFNCT--DVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
            PG+     D+DECK  P  C  GQCINT GS+ C C   Y     GT+C D  +     K
Sbjct: 1505 PGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPK 1564

Query: 59   VDLRSGTETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGG 113
                     C++++   +      C C  G      G  C    E  ++ +  + LC   
Sbjct: 1565 ----PCNYICKNTEGSYQ------CSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNT 1614

Query: 114  PGYQPVLEPPSYV---VTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXX 169
             G      PP +        D +EC +   LC A G C NT GSF C C  G+SL     
Sbjct: 1615 LGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGL 1674

Query: 170  XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQNLSTN 220
                         C  G C+N+ G Y C CP+GY+     +Q + +N  +N
Sbjct: 1675 NCEDVDECDGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSN 1724



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 69/222 (31%), Positives = 93/222 (41%), Gaps = 24/222 (10%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
            D+DECK  P  C  G CIN  GS+ C CP  +         Y+     C    +  +G  
Sbjct: 872  DIDECKEIPGICANGVCINQIGSFRCECPTGFS--------YNDLLLVCEDIDECSNGDN 923

Query: 67   TC-RDSDELSEDGTMAACCCSVG--AAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQPV 119
             C R++D ++  G+   C C+ G   +    C   + C E  +     LC    G YQ +
Sbjct: 924  LCQRNADCINSPGSYR-CECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCI 982

Query: 120  LE---PPSYVVTLA-DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                   S   T+  D+DEC  H   C +GTC NT GS+ C C  G+ L           
Sbjct: 983  CHNGFKASQDQTMCMDVDECERHP--CGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDE 1040

Query: 176  -XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
                   VC  G C N  GS+ CLC EGY   P+G   +  N
Sbjct: 1041 CSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTN 1082



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 67/217 (30%), Positives = 95/217 (43%), Gaps = 22/217 (10%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCY 56
            G  C D+DEC++ Q +CQ+  C+NT G +TC+CPP +      TAC D     S+ + C 
Sbjct: 1591 GKTCKDLDECQTKQHNCQF-LCVNTLGGFTCKCPPGF--TQHHTACIDNNECGSQPSLCG 1647

Query: 57   GKVDLRS--GTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
             K   ++  G+ +C      S D T    C  V    GN+ C    +     YR  CP  
Sbjct: 1648 AKGICQNTPGSFSCECQRGFSLDAT-GLNCEDVDECDGNHRCQHGCQNILGGYRCGCP-- 1704

Query: 114  PGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XX 172
             GY    +    V    D +EC ++   C   +C NT GS+ C C +G+S          
Sbjct: 1705 QGYIQHYQWNQCV----DENEC-SNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHD 1759

Query: 173  XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                    + C  G C N  G Y+C CP GY  +  G
Sbjct: 1760 VNECSSSKNPCNYG-CSNTEGGYLCGCPPGYYRVGQG 1795



 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 66/220 (30%), Positives = 90/220 (40%), Gaps = 25/220 (11%)

Query: 8    DVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
            DV+EC +SP  C  GQCINT GS+ C CP  Y L   G  C D+ +      +    G  
Sbjct: 1235 DVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDEC----SIGNPCGNG 1290

Query: 67   TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL-----CPGGPGYQPVLE 121
            TC +     E      C C+ G   G   + C +    A   L     C    G      
Sbjct: 1291 TCTNVIGSFE------CNCNEGFEPGPMMN-CEDINECAQNPLLCAFRCMNTFGSYECTC 1343

Query: 122  PPSYVVT-----LADIDECAA--HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
            P  Y +        D+DECA   H+       C N  G+F+C C  G +  P        
Sbjct: 1344 PIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDE 1403

Query: 175  XX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
                 +P +C  G C N+ GSY C C EG+ +  +G++ L
Sbjct: 1404 NECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECL 1443



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 64/209 (30%), Positives = 81/209 (38%), Gaps = 45/209 (21%)

Query: 3   GFNCTDVDECKS-PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C D+DEC +    C    QC+NT GSY C C   +    DG  C D           
Sbjct: 467 GIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF--TGDGFTCSD----------- 513

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
                + C ++  L E+G     C +V             PG  AYR  C    G+ P  
Sbjct: 514 ----VDECAENINLCENGQ----CLNV-------------PG--AYR--CECEMGFTPAS 548

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
           +  S      DIDEC + + +C  GTC N  G F C C  G+ L               P
Sbjct: 549 DSRS----CQDIDEC-SFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADP 603

Query: 181 DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
             C  G+C N PG Y C CP  +   P G
Sbjct: 604 INCVNGLCVNTPGRYECNCPPDFQLNPTG 632



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 4/97 (4%)

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP-- 180
            P  ++   DI+ECA +  LCA   C NTFGS+ CTC  G++L                  
Sbjct: 1309 PGPMMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLH 1367

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
            D    G+ C+NL G+++C+CP G    P+G   + +N
Sbjct: 1368 DCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDEN 1404



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 56/221 (25%), Positives = 77/221 (34%), Gaps = 19/221 (8%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARC-Y 56
           GF C+DVDEC ++   C+ GQC+N  G+Y C C   +   SD  +C D    S +  C +
Sbjct: 508 GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVF 567

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
           G  +   G   C   D    D T   C            D C +P       LC   PG 
Sbjct: 568 GTCNNLPGMFHCICDDGYELDRTGGNC---------TDIDECADP-INCVNGLCVNTPGR 617

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
                PP + +    +       G C         GS  C    G  ++           
Sbjct: 618 YECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKA 677

Query: 177 XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQNL 217
              P    P V       Y  LCP G    PN    +L+++
Sbjct: 678 WGNPCETCPPVNST---EYYTLCPGGEGFRPNPITIILEDI 715



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 44/168 (26%), Positives = 60/168 (35%), Gaps = 14/168 (8%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARCYG 57
            G  C D DEC     C  G C N  GS+ C C   +E        D   C  +     + 
Sbjct: 1272 GVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFR 1331

Query: 58   KVDLRSGTE-TCRDSDELSEDGTMAACC--CSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
             ++     E TC     L ED  M      C+ G           +     +  +CP G 
Sbjct: 1332 CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGM 1391

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGW 162
              +P  E         D +EC    G+C +G C N  GS+ C C  G+
Sbjct: 1392 ARRPDGE------GCVDENECRTKPGICENGRCVNIIGSYRCECNEGF 1433



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 22/49 (44%), Positives = 29/49 (59%), Gaps = 2/49 (4%)

Query: 2    PGFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
            P  NC D++EC ++P  C + +C+NT GSY C CP  Y L  D   C D
Sbjct: 1311 PMMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKD 1358


>AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form
            precursor transcript variant 3 protein.
          Length = 2809

 Score =  193 bits (471), Expect = 4e-49
 Identities = 90/209 (43%), Positives = 112/209 (53%), Gaps = 6/209 (2%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G NCTD++EC  P +C  G CINT GSY C CP ++EL   G  C D+R   C+ +   R
Sbjct: 1440 GGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDR 1499

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
             G      S E+    T A+CCCS+G AWGN C+ CP   +  YR LCPGG G+Q    P
Sbjct: 1500 -GDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQ----P 1554

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPD 181
                V L DIDEC    GLC  G C NTFGSF C C  G+ L+                 
Sbjct: 1555 NRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSS 1614

Query: 182  VCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
            +CGPG C N  G+Y C+CP  Y+ +  G+
Sbjct: 1615 ICGPGTCYNTLGNYTCVCPAEYLQVNGGN 1643



 Score =  162 bits (393), Expect = 1e-39
 Identities = 83/205 (40%), Positives = 104/205 (50%), Gaps = 9/205 (4%)

Query: 1    MPGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            M G  C DV+EC+S P  C  G+C+NT GS+ C CP    L + G  C D R   C+   
Sbjct: 862  MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCF--- 918

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
             LR   + C  +  L     M  CCCS+GA WG  C+ CP+P S  +  LCP G G+   
Sbjct: 919  -LRWDEDECGVT--LPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS- 974

Query: 120  LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXX 178
             +  S      D++EC    GLC HGTC NT GSF C C  G++L A             
Sbjct: 975  RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGY 203
             PD+CG G C N PGS+ C C  GY
Sbjct: 1035 SPDLCGQGTCVNTPGSFECECFPGY 1059



 Score =  153 bits (370), Expect = 7e-37
 Identities = 80/209 (38%), Positives = 106/209 (50%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  CTD +EC + P  C  G+C+NT GS+ C C   ++     T C+D R+  C+ +V L
Sbjct: 2247 GEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV-L 2305

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++    CR     SE  T A CCC  G  WG  C+ CP PG+ AYR+LCP G G      
Sbjct: 2306 QT---MCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSG------ 2356

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               Y     D+DEC     LCAHG C N+ GSF C C AG++  A              P
Sbjct: 2357 ---YTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP 2413

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GS++C CP GY+   +G
Sbjct: 2414 KPC-TFLCKNTKGSFLCSCPRGYLLEEDG 2441



 Score =  147 bits (357), Expect = 2e-35
 Identities = 71/202 (35%), Positives = 106/202 (52%), Gaps = 14/202 (6%)

Query: 5    NCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D+DEC + P  C +G C N+ GS+ C CPP + L  +G  C+D+R++ C+ +     
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRF---- 2021

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
              E  + S   + + T   CCCS   G  WG+ C+ CP+ GS A+++LCP G G  P  +
Sbjct: 2022 --EAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPD 2079

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
                  +  D++ECA + G+C +G C NT GSF C C  G+SL                 
Sbjct: 2080 D-----SREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGH 2134

Query: 182  VCGPGVCRNLPGSYVCLCPEGY 203
             CG G C N+ G + C C +G+
Sbjct: 2135 PCGQGTCTNVIGGFECACADGF 2156



 Score =  138 bits (333), Expect = 2e-32
 Identities = 79/211 (37%), Positives = 102/211 (48%), Gaps = 17/211 (8%)

Query: 6    CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC +  S C  G C NT G+YTC CP  Y  V+ G  C D RK+ C+     R  
Sbjct: 1603 CEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCF-----RHY 1657

Query: 65   TETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPG-GPGYQPVLE 121
              TC+  +EL+ + T   CCCS  +G AW   C+ CP P S  Y+ LC    PG+   + 
Sbjct: 1658 NGTCQ--NELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIH 1715

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                +    DIDEC     +CA+G C N  GSF C C AG++  +             R 
Sbjct: 1716 TGKPL----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRE 1771

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGS 210
              C     C N+PGSY C C  GY   P G+
Sbjct: 1772 SPCQQNADCINIPGSYRCKCTRGYKLSPGGA 1802



 Score =  120 bits (290), Expect = 3e-27
 Identities = 65/203 (32%), Positives = 91/203 (44%), Gaps = 16/203 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  C D+DEC++P  C  G C NT+GS+ C+C     + +DG  C D+  ++ CYG ++ 
Sbjct: 567 GHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEK 626

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            S       +   SE      CC +    +G  C  CP   S  ++ LC  G G      
Sbjct: 627 GSCARPFPGTVTKSE-----CCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLG------ 675

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                    DI+ECA    +CA+G C N  GS+ C C  G+   A               
Sbjct: 676 ---ITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732

Query: 181 DVCGPGVCRNLPGSYVCLCPEGY 203
            +C  G C+N PGSY C CP G+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGF 755



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 72/222 (32%), Positives = 95/222 (42%), Gaps = 32/222 (14%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  G C+NT GS+ C C P YE    G     +    C    +   
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYE---SGFMLMKN----CMDVDECAR 1077

Query: 64   GTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPE--------PGSEAYRQL--- 109
                CR     + DG+   C C  G    A G  C+   E        P  +    +   
Sbjct: 1078 DPLLCRGGTCTNTDGSYK-CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAF 1136

Query: 110  -CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPX 167
             C    G+Q   +    V    DI+EC    G C  H  C NT GS+ C+CG G+SL P 
Sbjct: 1137 QCSCHAGFQSTPDRQGCV----DINECRVQNGGCDVH--CINTEGSYRCSCGQGYSLMPD 1190

Query: 168  XXXXXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                         P VC  G C N+PG + CLC +G++A P+
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232



 Score = 99.1 bits (236), Expect = 1e-20
 Identities = 70/214 (32%), Positives = 92/214 (42%), Gaps = 20/214 (9%)

Query: 6    CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            C+DVDEC+    +C  +  C+N  GS++CRC P +  V DG  C+D  +  C  +    S
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECHDLDE--CVSQEHRCS 1333

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQPV 119
                C     L+  G+    C    A  G +C   D C E         C   PG Y+  
Sbjct: 1334 PRGDC-----LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCE 1388

Query: 120  LE----PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E    P        D+DECA    LCA G+C N  G F C C  G+ L           
Sbjct: 1389 CEMGFDPTEDHRACQDVDECA-QGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDIN 1447

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                P  C  GVC N PGSY+C CP+ +   P+G
Sbjct: 1448 ECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 59/160 (36%), Positives = 74/160 (46%), Gaps = 22/160 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC S   C  G C N  GSYTC+C P   L   GT C DS K  C+ K+      
Sbjct: 764 CKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKI------ 816

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-EPGSEAYRQLCPGGPGYQPVLEPPS 124
           +  R    L      + CC ++GAAWG+ C+ C  +P        C  G           
Sbjct: 817 QESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPA-------CARGFARMT------ 863

Query: 125 YVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
             VT  D++EC +  G+C +G C NT GSF C C  G  L
Sbjct: 864 -GVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLML 902



 Score = 89.8 bits (213), Expect = 7e-18
 Identities = 63/215 (29%), Positives = 88/215 (40%), Gaps = 22/215 (10%)

Query: 3    GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVD 60
            G  C D+DEC  S   C +GQC+N  G++ C C   ++   D   C D  + R   G  D
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167

Query: 61   LRS-GTE-----TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
            +    TE     +C     L  DG     C  V     + C+  P    + +    PGG 
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGR---ACADV-----DECEENPRVCDQGHCTNMPGGH 1219

Query: 115  G---YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX-- 169
                Y   +  P  + T  D+DEC  +  +C HG C NT GSFVC C  G+ +       
Sbjct: 1220 RCLCYDGFMATPD-MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGC 1278

Query: 170  XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +      C N+PGS+ C C  G+V
Sbjct: 1279 SDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV 1313



 Score = 86.6 bits (205), Expect = 6e-17
 Identities = 65/219 (29%), Positives = 93/219 (42%), Gaps = 22/219 (10%)

Query: 2    PGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCY 56
            PG  C   +EC+  P  C +G C++T+GSY C C   ++  +D T C D     R+    
Sbjct: 1799 PGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGN 1858

Query: 57   GKVDLRSGTETCR--DSDELSEDGTMA---ACCCSVGAAWG-NYCDPCPEPGSEAYRQLC 110
            G      G+  C       ++ +G       C   VG      +C      GS  +  LC
Sbjct: 1859 GTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHC--LNTAGS--FHCLC 1914

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
              G  ++   +  + V    D +EC +  G C  GTC N  GSF C C  G+ +      
Sbjct: 1915 QDG--FELTADGKNCV----DTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQ-SDHC 1967

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     P++C  G C N PGS+ CLCP G+V   NG
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 67/219 (30%), Positives = 90/219 (41%), Gaps = 21/219 (9%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
            DVDEC+     C +G+CIN+ GS+ C C   Y   +  T C D  +     K      T 
Sbjct: 2363 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPK----PCTF 2418

Query: 67   TCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGGPGYQPVLE 121
             C+++      G+   C C  G      G  C    E  S  +  + LC    G      
Sbjct: 2419 LCKNTK-----GSFL-CSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRC 2472

Query: 122  PPSYVV---TLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
            PP +        D DEC+A  G C AHG C NT GSF C C  G++L             
Sbjct: 2473 PPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532

Query: 178  XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
              P  C  G C+N  G Y C CP+G+      +Q + +N
Sbjct: 2533 DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDEN 2570



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 48/125 (38%), Positives = 60/125 (48%), Gaps = 16/125 (12%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DVDEC++ P  CQ G C+N  GS+ CRCP  + L     AC D R   C+    L  G
Sbjct: 245 CQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSV--LFGG 302

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQLC-------PGGPG 115
               R + +L+   T   CCC  G  W  G   + CP  GS  ++QLC       PG PG
Sbjct: 303 ----RCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPG 358

Query: 116 YQPVL 120
             P L
Sbjct: 359 LFPGL 363



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 63/220 (28%), Positives = 87/220 (39%), Gaps = 27/220 (12%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
            G  C D+DEC S Q +CQ+  C+NT G++TCRCPP +       AC+D+ +         
Sbjct: 2441 GRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGF--TQHHQACFDNDECSAQPGPCG 2497

Query: 56   -YGKVDLRSGTETCRDSDELSEDGTMAAC---CCSVGAAWGNY-CDPCPEPGSEAYRQLC 110
             +G      G+  C    E  +  T+ +    C  V    G + C    +     YR  C
Sbjct: 2498 AHGHCHNTPGSFRC----ECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSC 2553

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
            P G          S      D +ECA     C   +C NT G F C C +G+        
Sbjct: 2554 PQG------FTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607

Query: 171  XXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     R   C    C N PG ++C CP+GY     G
Sbjct: 2608 CQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQG 2646



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 63/210 (30%), Positives = 85/210 (40%), Gaps = 25/210 (11%)

Query: 6    CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCYGKV 59
            C D+DEC   P+ C +  C NT+GS+ C CP  Y L  DG  C D     SR+  C    
Sbjct: 2403 CLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLC 2461

Query: 60   DLRSGTETCRDSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
                G  TCR     ++     AC     C +     G +      PGS  +R  C    
Sbjct: 2462 VNTVGAFTCRCPPGFTQH--HQACFDNDECSAQPGPCGAHGHCHNTPGS--FR--CECHQ 2515

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXX 173
            G+  V    S      D++EC      C HG C N  G + C+C  G++  +        
Sbjct: 2516 GFTLV----SSGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDE 2569

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  CG   CRN  G + C+CP G+
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGF 2599



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 58/167 (34%), Positives = 74/167 (44%), Gaps = 23/167 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-----ARCY-GKV 59
           C DVDEC S   C +G C+N  G+Y CRC P ++      AC D  +       C+ G+ 
Sbjct: 447 CIDVDECTS-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505

Query: 60  DLRSGTE--TCRDSDELSEDGTMAAC---CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
               G+    C    ELS DG        C +        C    E GS  +  LC   P
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVC--LNEDGS--FSCLCK--P 559

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
           G+  +L P  +     DIDEC    G+C +G CTNT GSF C C  G
Sbjct: 560 GF--LLAPGGHY--CMDIDECQT-PGICVNGHCTNTEGSFRCQCLGG 601



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 54/175 (30%), Positives = 65/175 (37%), Gaps = 19/175 (10%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARCYG 57
            G NC D DEC     C  G C N  G + C C   +E        D   C       C  
Sbjct: 2121 GINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDEC-SLNPLLCAF 2179

Query: 58   KVDLRSGTE--TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CP 111
            +     G+   TC     L EDG M   C  V        D C   G E    +    C 
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAM---CRDVDECADGQQD-CHARGMECKNLIGTFACV 2235

Query: 112  GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              PG +P+   P       D +EC A   LC +G C NT GSF C C  G+  +P
Sbjct: 2236 CPPGMRPL---PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSP 2287



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 19/210 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC D +EC +   C  G C+N  GS++C C P + L   G  C D  + +  G     
Sbjct: 526 GKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPG----- 580

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
                C +    + +G+   C C  G A G     C +      R  C G         P
Sbjct: 581 ----ICVNGHCTNTEGSFR-CQCLGGLAVGTDGRVCVDTH---VRSTCYGAIEKGSCARP 632

Query: 123 PSYVVTLADIDECAAHEGL---CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
               VT ++        G    C      N+   F   C +G  L               
Sbjct: 633 FPGTVTKSECCCANPDHGFGEPCQLCPAKNS-AEFQALCSSG--LGITTDGRDINECALD 689

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P+VC  GVC NL GSY C+C  GY A  +G
Sbjct: 690 PEVCANGVCENLRGSYRCVCNLGYEAGASG 719



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 59/187 (31%), Positives = 73/187 (39%), Gaps = 28/187 (14%)

Query: 21  GQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSGTETCRDSDELSEDGT 79
           G+CI   G   C C   +     G  C  D R   C+G+V    G E C+         T
Sbjct: 159 GRCI---GPNRCACVYGFM----GPQCERDYRTGPCFGQV----GPEGCQHQ-LTGLVCT 206

Query: 80  MAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHE 139
            A CC +VG AWG  C+ CP        Q  P   G+ P +    +     D+DEC A  
Sbjct: 207 KALCCATVGRAWGLPCELCPA-------QPHPCRRGFIPNI----HTGACQDVDECQAVP 255

Query: 140 GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR-NLPGSYV-- 196
           GLC  G+C N  GSF C C  G  L+                V   G C  +L G Y   
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRR 315

Query: 197 -CLCPEG 202
            C C  G
Sbjct: 316 QCCCDRG 322



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 26/177 (14%)

Query: 3    GFNCTDVDECKSPQ-SCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            GF C D+DEC S +  C   G C+N  GSY C C   +    DG  C D  +  C   VD
Sbjct: 1316 GFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCED--RDECAENVD 1371

Query: 61   LRSGTETC------RDSDELSEDGT--MAACCCSVGAAWGNYC--DPCPE-PGSEAYRQL 109
            L    +        R   E+  D T    AC      A GN C    C   PG   +R +
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPG--MFRCI 1429

Query: 110  CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
            C G  GY+  L+      T  DI+ECA     C +G C NT GS++C+C   + L P
Sbjct: 1430 CNG--GYE--LDRGGGNCT--DINECADPVN-CINGVCINTPGSYLCSCPQDFELNP 1479



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 61/210 (29%), Positives = 77/210 (36%), Gaps = 19/210 (9%)

Query: 9   VDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCY-GKVDLRS 63
           +D C+     C  G+C+ T  SY C C   Y     G  C D      + C+ G      
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHGDCVNIP 467

Query: 64  GTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           GT  CR         T  AC     C V    G  C       +E   Q C    G++  
Sbjct: 468 GTYHCRCYPGFQATPTRQACVDVDECIVS---GGLCHLGRCVNTEGSFQ-CVCNAGFE-- 521

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
           L P        D +ECA    +C +G C N  GSF C C  G+ LAP             
Sbjct: 522 LSPDGK--NCVDHNECATST-MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQT 578

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P +C  G C N  GS+ C C  G     +G
Sbjct: 579 PGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D+DECA +  LC +G C N+ GS+ C+C  G+                    C  GVCRN
Sbjct: 724 DVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVSGVCRN 782

Query: 191 LPGSYVCLCPEGYVAMPNGSQYLLQNLSTNMRLKIQ 226
           L GSY C C  G    P+G+ + L +      LKIQ
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT-FCLDSTKGTCWLKIQ 817



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX--XXXRP 180
            P  ++T  DIDEC+ +  LCA   C NT GS++CTC AG++L                + 
Sbjct: 2158 PGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQ 2216

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQ 211
            D    G+ C+NL G++ C+CP G   +P   +
Sbjct: 2217 DCHARGMECKNLIGTFACVCPPGMRPLPGSGE 2248



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 131  DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXXXXXXRPDVCGPGVC 188
            DIDEC     LC  GTC NT GSF C C  G+                   P +C  G C
Sbjct: 1028 DIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTC 1087

Query: 189  RNLPGSYVCLCPEGYVAMPNGS 210
             N  GSY C CP G+     G+
Sbjct: 1088 TNTDGSYKCQCPPGHELTAKGT 1109



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 55/211 (26%), Positives = 77/211 (36%), Gaps = 27/211 (12%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +CTDVDEC  +   C  G C N+ GSY+C CPP +    D                  
Sbjct: 719 GKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQD------------------ 760

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE-PGSEAYRQLCPGGPGYQPVL 120
              TE C+D DE      ++  C ++  ++   C P      S  +      G  +  + 
Sbjct: 761 ---TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQ 817

Query: 121 EPPSYV-VTLADI-DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           E    V +  A +  EC A  G      C          C  G++               
Sbjct: 818 ESRCEVNLQGASLRSECCATLGAAWGSPCERC--EIDPACARGFARMTGVTCDDVNECES 875

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            P VC  G C N  GS+ C CPEG +   +G
Sbjct: 876 FPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 127  VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
            +   D DEC+     C  GTCTN  G F C C  G+                 P +C   
Sbjct: 2122 INCVDTDECSVGHP-CGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR 2180

Query: 187  VCRNLPGSYVCLCPEGYVAMPNGS 210
             C N  GSY+C CP GY    +G+
Sbjct: 2181 -CHNTEGSYLCTCPAGYTLREDGA 2203



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCR 189
           D+DEC +    C HG C N  G++ C C  G+   P                +C  G C 
Sbjct: 449 DVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCV 506

Query: 190 NLPGSYVCLCPEGYVAMPNGSQYLLQN 216
           N  GS+ C+C  G+   P+G   +  N
Sbjct: 507 NTEGSFQCVCNAGFELSPDGKNCVDHN 533



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 11/24 (45%), Positives = 15/24 (62%)

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P +C  G C N+ GS+ C CP G+
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGH 278


>AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form
            precursor transcript variant 2 protein.
          Length = 2809

 Score =  193 bits (471), Expect = 4e-49
 Identities = 90/209 (43%), Positives = 112/209 (53%), Gaps = 6/209 (2%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G NCTD++EC  P +C  G CINT GSY C CP ++EL   G  C D+R   C+ +   R
Sbjct: 1440 GGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDR 1499

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
             G      S E+    T A+CCCS+G AWGN C+ CP   +  YR LCPGG G+Q    P
Sbjct: 1500 -GDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQ----P 1554

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPD 181
                V L DIDEC    GLC  G C NTFGSF C C  G+ L+                 
Sbjct: 1555 NRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSS 1614

Query: 182  VCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
            +CGPG C N  G+Y C+CP  Y+ +  G+
Sbjct: 1615 ICGPGTCYNTLGNYTCVCPAEYLQVNGGN 1643



 Score =  162 bits (393), Expect = 1e-39
 Identities = 83/205 (40%), Positives = 104/205 (50%), Gaps = 9/205 (4%)

Query: 1    MPGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            M G  C DV+EC+S P  C  G+C+NT GS+ C CP    L + G  C D R   C+   
Sbjct: 862  MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCF--- 918

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
             LR   + C  +  L     M  CCCS+GA WG  C+ CP+P S  +  LCP G G+   
Sbjct: 919  -LRWDEDECGVT--LPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS- 974

Query: 120  LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXX 178
             +  S      D++EC    GLC HGTC NT GSF C C  G++L A             
Sbjct: 975  RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGY 203
             PD+CG G C N PGS+ C C  GY
Sbjct: 1035 SPDLCGQGTCVNTPGSFECECFPGY 1059



 Score =  153 bits (370), Expect = 7e-37
 Identities = 80/209 (38%), Positives = 106/209 (50%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  CTD +EC + P  C  G+C+NT GS+ C C   ++     T C+D R+  C+ +V L
Sbjct: 2247 GEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV-L 2305

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++    CR     SE  T A CCC  G  WG  C+ CP PG+ AYR+LCP G G      
Sbjct: 2306 QT---MCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSG------ 2356

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               Y     D+DEC     LCAHG C N+ GSF C C AG++  A              P
Sbjct: 2357 ---YTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP 2413

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GS++C CP GY+   +G
Sbjct: 2414 KPC-TFLCKNTKGSFLCSCPRGYLLEEDG 2441



 Score =  147 bits (357), Expect = 2e-35
 Identities = 71/202 (35%), Positives = 106/202 (52%), Gaps = 14/202 (6%)

Query: 5    NCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D+DEC + P  C +G C N+ GS+ C CPP + L  +G  C+D+R++ C+ +     
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRF---- 2021

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
              E  + S   + + T   CCCS   G  WG+ C+ CP+ GS A+++LCP G G  P  +
Sbjct: 2022 --EAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPD 2079

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
                  +  D++ECA + G+C +G C NT GSF C C  G+SL                 
Sbjct: 2080 D-----SREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGH 2134

Query: 182  VCGPGVCRNLPGSYVCLCPEGY 203
             CG G C N+ G + C C +G+
Sbjct: 2135 PCGQGTCTNVIGGFECACADGF 2156



 Score =  138 bits (333), Expect = 2e-32
 Identities = 79/211 (37%), Positives = 102/211 (48%), Gaps = 17/211 (8%)

Query: 6    CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC +  S C  G C NT G+YTC CP  Y  V+ G  C D RK+ C+     R  
Sbjct: 1603 CEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCF-----RHY 1657

Query: 65   TETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPG-GPGYQPVLE 121
              TC+  +EL+ + T   CCCS  +G AW   C+ CP P S  Y+ LC    PG+   + 
Sbjct: 1658 NGTCQ--NELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIH 1715

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                +    DIDEC     +CA+G C N  GSF C C AG++  +             R 
Sbjct: 1716 TGKPL----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRE 1771

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGS 210
              C     C N+PGSY C C  GY   P G+
Sbjct: 1772 SPCQQNADCINIPGSYRCKCTRGYKLSPGGA 1802



 Score =  120 bits (290), Expect = 3e-27
 Identities = 65/203 (32%), Positives = 91/203 (44%), Gaps = 16/203 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  C D+DEC++P  C  G C NT+GS+ C+C     + +DG  C D+  ++ CYG ++ 
Sbjct: 567 GHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEK 626

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            S       +   SE      CC +    +G  C  CP   S  ++ LC  G G      
Sbjct: 627 GSCARPFPGTVTKSE-----CCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLG------ 675

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                    DI+ECA    +CA+G C N  GS+ C C  G+   A               
Sbjct: 676 ---ITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732

Query: 181 DVCGPGVCRNLPGSYVCLCPEGY 203
            +C  G C+N PGSY C CP G+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGF 755



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 72/222 (32%), Positives = 95/222 (42%), Gaps = 32/222 (14%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  G C+NT GS+ C C P YE    G     +    C    +   
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYE---SGFMLMKN----CMDVDECAR 1077

Query: 64   GTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPE--------PGSEAYRQL--- 109
                CR     + DG+   C C  G    A G  C+   E        P  +    +   
Sbjct: 1078 DPLLCRGGTCTNTDGSYK-CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAF 1136

Query: 110  -CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPX 167
             C    G+Q   +    V    DI+EC    G C  H  C NT GS+ C+CG G+SL P 
Sbjct: 1137 QCSCHAGFQSTPDRQGCV----DINECRVQNGGCDVH--CINTEGSYRCSCGQGYSLMPD 1190

Query: 168  XXXXXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                         P VC  G C N+PG + CLC +G++A P+
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232



 Score = 99.1 bits (236), Expect = 1e-20
 Identities = 70/214 (32%), Positives = 92/214 (42%), Gaps = 20/214 (9%)

Query: 6    CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            C+DVDEC+    +C  +  C+N  GS++CRC P +  V DG  C+D  +  C  +    S
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECHDLDE--CVSQEHRCS 1333

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQPV 119
                C     L+  G+    C    A  G +C   D C E         C   PG Y+  
Sbjct: 1334 PRGDC-----LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCE 1388

Query: 120  LE----PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E    P        D+DECA    LCA G+C N  G F C C  G+ L           
Sbjct: 1389 CEMGFDPTEDHRACQDVDECA-QGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDIN 1447

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                P  C  GVC N PGSY+C CP+ +   P+G
Sbjct: 1448 ECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 59/160 (36%), Positives = 74/160 (46%), Gaps = 22/160 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC S   C  G C N  GSYTC+C P   L   GT C DS K  C+ K+      
Sbjct: 764 CKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKI------ 816

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-EPGSEAYRQLCPGGPGYQPVLEPPS 124
           +  R    L      + CC ++GAAWG+ C+ C  +P        C  G           
Sbjct: 817 QESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPA-------CARGFARMT------ 863

Query: 125 YVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
             VT  D++EC +  G+C +G C NT GSF C C  G  L
Sbjct: 864 -GVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLML 902



 Score = 89.8 bits (213), Expect = 7e-18
 Identities = 63/215 (29%), Positives = 88/215 (40%), Gaps = 22/215 (10%)

Query: 3    GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVD 60
            G  C D+DEC  S   C +GQC+N  G++ C C   ++   D   C D  + R   G  D
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167

Query: 61   LRS-GTE-----TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
            +    TE     +C     L  DG     C  V     + C+  P    + +    PGG 
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGR---ACADV-----DECEENPRVCDQGHCTNMPGGH 1219

Query: 115  G---YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX-- 169
                Y   +  P  + T  D+DEC  +  +C HG C NT GSFVC C  G+ +       
Sbjct: 1220 RCLCYDGFMATPD-MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGC 1278

Query: 170  XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +      C N+PGS+ C C  G+V
Sbjct: 1279 SDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV 1313



 Score = 86.6 bits (205), Expect = 6e-17
 Identities = 65/219 (29%), Positives = 93/219 (42%), Gaps = 22/219 (10%)

Query: 2    PGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCY 56
            PG  C   +EC+  P  C +G C++T+GSY C C   ++  +D T C D     R+    
Sbjct: 1799 PGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGN 1858

Query: 57   GKVDLRSGTETCR--DSDELSEDGTMA---ACCCSVGAAWG-NYCDPCPEPGSEAYRQLC 110
            G      G+  C       ++ +G       C   VG      +C      GS  +  LC
Sbjct: 1859 GTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHC--LNTAGS--FHCLC 1914

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
              G  ++   +  + V    D +EC +  G C  GTC N  GSF C C  G+ +      
Sbjct: 1915 QDG--FELTADGKNCV----DTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQ-SDHC 1967

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     P++C  G C N PGS+ CLCP G+V   NG
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 67/219 (30%), Positives = 90/219 (41%), Gaps = 21/219 (9%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
            DVDEC+     C +G+CIN+ GS+ C C   Y   +  T C D  +     K      T 
Sbjct: 2363 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPK----PCTF 2418

Query: 67   TCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGGPGYQPVLE 121
             C+++      G+   C C  G      G  C    E  S  +  + LC    G      
Sbjct: 2419 LCKNTK-----GSFL-CSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRC 2472

Query: 122  PPSYVV---TLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
            PP +        D DEC+A  G C AHG C NT GSF C C  G++L             
Sbjct: 2473 PPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532

Query: 178  XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
              P  C  G C+N  G Y C CP+G+      +Q + +N
Sbjct: 2533 DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDEN 2570



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 48/125 (38%), Positives = 60/125 (48%), Gaps = 16/125 (12%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DVDEC++ P  CQ G C+N  GS+ CRCP  + L     AC D R   C+    L  G
Sbjct: 245 CQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSV--LFGG 302

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQLC-------PGGPG 115
               R + +L+   T   CCC  G  W  G   + CP  GS  ++QLC       PG PG
Sbjct: 303 ----RCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPG 358

Query: 116 YQPVL 120
             P L
Sbjct: 359 LFPGL 363



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 63/220 (28%), Positives = 87/220 (39%), Gaps = 27/220 (12%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
            G  C D+DEC S Q +CQ+  C+NT G++TCRCPP +       AC+D+ +         
Sbjct: 2441 GRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGF--TQHHQACFDNDECSAQPGPCG 2497

Query: 56   -YGKVDLRSGTETCRDSDELSEDGTMAAC---CCSVGAAWGNY-CDPCPEPGSEAYRQLC 110
             +G      G+  C    E  +  T+ +    C  V    G + C    +     YR  C
Sbjct: 2498 AHGHCHNTPGSFRC----ECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSC 2553

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
            P G          S      D +ECA     C   +C NT G F C C +G+        
Sbjct: 2554 PQG------FTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607

Query: 171  XXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     R   C    C N PG ++C CP+GY     G
Sbjct: 2608 CQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQG 2646



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 63/210 (30%), Positives = 85/210 (40%), Gaps = 25/210 (11%)

Query: 6    CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCYGKV 59
            C D+DEC   P+ C +  C NT+GS+ C CP  Y L  DG  C D     SR+  C    
Sbjct: 2403 CLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLC 2461

Query: 60   DLRSGTETCRDSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
                G  TCR     ++     AC     C +     G +      PGS  +R  C    
Sbjct: 2462 VNTVGAFTCRCPPGFTQH--HQACFDNDECSAQPGPCGAHGHCHNTPGS--FR--CECHQ 2515

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXX 173
            G+  V    S      D++EC      C HG C N  G + C+C  G++  +        
Sbjct: 2516 GFTLV----SSGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDE 2569

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  CG   CRN  G + C+CP G+
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGF 2599



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 58/167 (34%), Positives = 74/167 (44%), Gaps = 23/167 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-----ARCY-GKV 59
           C DVDEC S   C +G C+N  G+Y CRC P ++      AC D  +       C+ G+ 
Sbjct: 447 CIDVDECTS-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505

Query: 60  DLRSGTE--TCRDSDELSEDGTMAAC---CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
               G+    C    ELS DG        C +        C    E GS  +  LC   P
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVC--LNEDGS--FSCLCK--P 559

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
           G+  +L P  +     DIDEC    G+C +G CTNT GSF C C  G
Sbjct: 560 GF--LLAPGGHY--CMDIDECQT-PGICVNGHCTNTEGSFRCQCLGG 601



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 54/175 (30%), Positives = 65/175 (37%), Gaps = 19/175 (10%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARCYG 57
            G NC D DEC     C  G C N  G + C C   +E        D   C       C  
Sbjct: 2121 GINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDEC-SLNPLLCAF 2179

Query: 58   KVDLRSGTE--TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CP 111
            +     G+   TC     L EDG M   C  V        D C   G E    +    C 
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAM---CRDVDECADGQQD-CHARGMECKNLIGTFACV 2235

Query: 112  GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              PG +P+   P       D +EC A   LC +G C NT GSF C C  G+  +P
Sbjct: 2236 CPPGMRPL---PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSP 2287



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 19/210 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC D +EC +   C  G C+N  GS++C C P + L   G  C D  + +  G     
Sbjct: 526 GKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPG----- 580

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
                C +    + +G+   C C  G A G     C +      R  C G         P
Sbjct: 581 ----ICVNGHCTNTEGSFR-CQCLGGLAVGTDGRVCVDTH---VRSTCYGAIEKGSCARP 632

Query: 123 PSYVVTLADIDECAAHEGL---CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
               VT ++        G    C      N+   F   C +G  L               
Sbjct: 633 FPGTVTKSECCCANPDHGFGEPCQLCPAKNS-AEFQALCSSG--LGITTDGRDINECALD 689

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P+VC  GVC NL GSY C+C  GY A  +G
Sbjct: 690 PEVCANGVCENLRGSYRCVCNLGYEAGASG 719



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 59/187 (31%), Positives = 73/187 (39%), Gaps = 28/187 (14%)

Query: 21  GQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSGTETCRDSDELSEDGT 79
           G+CI   G   C C   +     G  C  D R   C+G+V    G E C+         T
Sbjct: 159 GRCI---GPNRCACVYGFM----GPQCERDYRTGPCFGQV----GPEGCQHQ-LTGLVCT 206

Query: 80  MAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHE 139
            A CC +VG AWG  C+ CP        Q  P   G+ P +    +     D+DEC A  
Sbjct: 207 KALCCATVGRAWGLPCELCPA-------QPHPCRRGFIPNI----HTGACQDVDECQAVP 255

Query: 140 GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR-NLPGSYV-- 196
           GLC  G+C N  GSF C C  G  L+                V   G C  +L G Y   
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRR 315

Query: 197 -CLCPEG 202
            C C  G
Sbjct: 316 QCCCDRG 322



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 26/177 (14%)

Query: 3    GFNCTDVDECKSPQ-SCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            GF C D+DEC S +  C   G C+N  GSY C C   +    DG  C D  +  C   VD
Sbjct: 1316 GFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCED--RDECAENVD 1371

Query: 61   LRSGTETC------RDSDELSEDGT--MAACCCSVGAAWGNYC--DPCPE-PGSEAYRQL 109
            L    +        R   E+  D T    AC      A GN C    C   PG   +R +
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPG--MFRCI 1429

Query: 110  CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
            C G  GY+  L+      T  DI+ECA     C +G C NT GS++C+C   + L P
Sbjct: 1430 CNG--GYE--LDRGGGNCT--DINECADPVN-CINGVCINTPGSYLCSCPQDFELNP 1479



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 61/210 (29%), Positives = 77/210 (36%), Gaps = 19/210 (9%)

Query: 9   VDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCY-GKVDLRS 63
           +D C+     C  G+C+ T  SY C C   Y     G  C D      + C+ G      
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHGDCVNIP 467

Query: 64  GTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           GT  CR         T  AC     C V    G  C       +E   Q C    G++  
Sbjct: 468 GTYHCRCYPGFQATPTRQACVDVDECIVS---GGLCHLGRCVNTEGSFQ-CVCNAGFE-- 521

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
           L P        D +ECA    +C +G C N  GSF C C  G+ LAP             
Sbjct: 522 LSPDGK--NCVDHNECATST-MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQT 578

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P +C  G C N  GS+ C C  G     +G
Sbjct: 579 PGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D+DECA +  LC +G C N+ GS+ C+C  G+                    C  GVCRN
Sbjct: 724 DVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVSGVCRN 782

Query: 191 LPGSYVCLCPEGYVAMPNGSQYLLQNLSTNMRLKIQ 226
           L GSY C C  G    P+G+ + L +      LKIQ
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT-FCLDSTKGTCWLKIQ 817



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX--XXXRP 180
            P  ++T  DIDEC+ +  LCA   C NT GS++CTC AG++L                + 
Sbjct: 2158 PGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQ 2216

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQ 211
            D    G+ C+NL G++ C+CP G   +P   +
Sbjct: 2217 DCHARGMECKNLIGTFACVCPPGMRPLPGSGE 2248



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 131  DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXXXXXXRPDVCGPGVC 188
            DIDEC     LC  GTC NT GSF C C  G+                   P +C  G C
Sbjct: 1028 DIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTC 1087

Query: 189  RNLPGSYVCLCPEGYVAMPNGS 210
             N  GSY C CP G+     G+
Sbjct: 1088 TNTDGSYKCQCPPGHELTAKGT 1109



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 55/211 (26%), Positives = 77/211 (36%), Gaps = 27/211 (12%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +CTDVDEC  +   C  G C N+ GSY+C CPP +    D                  
Sbjct: 719 GKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQD------------------ 760

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE-PGSEAYRQLCPGGPGYQPVL 120
              TE C+D DE      ++  C ++  ++   C P      S  +      G  +  + 
Sbjct: 761 ---TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQ 817

Query: 121 EPPSYV-VTLADI-DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           E    V +  A +  EC A  G      C          C  G++               
Sbjct: 818 ESRCEVNLQGASLRSECCATLGAAWGSPCERC--EIDPACARGFARMTGVTCDDVNECES 875

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            P VC  G C N  GS+ C CPEG +   +G
Sbjct: 876 FPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 127  VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
            +   D DEC+     C  GTCTN  G F C C  G+                 P +C   
Sbjct: 2122 INCVDTDECSVGHP-CGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR 2180

Query: 187  VCRNLPGSYVCLCPEGYVAMPNGS 210
             C N  GSY+C CP GY    +G+
Sbjct: 2181 -CHNTEGSYLCTCPAGYTLREDGA 2203



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCR 189
           D+DEC +    C HG C N  G++ C C  G+   P                +C  G C 
Sbjct: 449 DVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCV 506

Query: 190 NLPGSYVCLCPEGYVAMPNGSQYLLQN 216
           N  GS+ C+C  G+   P+G   +  N
Sbjct: 507 NTEGSFQCVCNAGFELSPDGKNCVDHN 533



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 11/24 (45%), Positives = 15/24 (62%)

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P +C  G C N+ GS+ C CP G+
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGH 278


>AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form
            precursor transcript variant 1 protein.
          Length = 2809

 Score =  193 bits (471), Expect = 4e-49
 Identities = 90/209 (43%), Positives = 112/209 (53%), Gaps = 6/209 (2%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G NCTD++EC  P +C  G CINT GSY C CP ++EL   G  C D+R   C+ +   R
Sbjct: 1440 GGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDR 1499

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
             G      S E+    T A+CCCS+G AWGN C+ CP   +  YR LCPGG G+Q    P
Sbjct: 1500 -GDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQ----P 1554

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPD 181
                V L DIDEC    GLC  G C NTFGSF C C  G+ L+                 
Sbjct: 1555 NRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSS 1614

Query: 182  VCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
            +CGPG C N  G+Y C+CP  Y+ +  G+
Sbjct: 1615 ICGPGTCYNTLGNYTCVCPAEYLQVNGGN 1643



 Score =  162 bits (393), Expect = 1e-39
 Identities = 83/205 (40%), Positives = 104/205 (50%), Gaps = 9/205 (4%)

Query: 1    MPGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            M G  C DV+EC+S P  C  G+C+NT GS+ C CP    L + G  C D R   C+   
Sbjct: 862  MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCF--- 918

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
             LR   + C  +  L     M  CCCS+GA WG  C+ CP+P S  +  LCP G G+   
Sbjct: 919  -LRWDEDECGVT--LPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS- 974

Query: 120  LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXX 178
             +  S      D++EC    GLC HGTC NT GSF C C  G++L A             
Sbjct: 975  RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGY 203
             PD+CG G C N PGS+ C C  GY
Sbjct: 1035 SPDLCGQGTCVNTPGSFECECFPGY 1059



 Score =  153 bits (370), Expect = 7e-37
 Identities = 80/209 (38%), Positives = 106/209 (50%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  CTD +EC + P  C  G+C+NT GS+ C C   ++     T C+D R+  C+ +V L
Sbjct: 2247 GEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV-L 2305

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++    CR     SE  T A CCC  G  WG  C+ CP PG+ AYR+LCP G G      
Sbjct: 2306 QT---MCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSG------ 2356

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               Y     D+DEC     LCAHG C N+ GSF C C AG++  A              P
Sbjct: 2357 ---YTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP 2413

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GS++C CP GY+   +G
Sbjct: 2414 KPC-TFLCKNTKGSFLCSCPRGYLLEEDG 2441



 Score =  147 bits (357), Expect = 2e-35
 Identities = 71/202 (35%), Positives = 106/202 (52%), Gaps = 14/202 (6%)

Query: 5    NCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D+DEC + P  C +G C N+ GS+ C CPP + L  +G  C+D+R++ C+ +     
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRF---- 2021

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
              E  + S   + + T   CCCS   G  WG+ C+ CP+ GS A+++LCP G G  P  +
Sbjct: 2022 --EAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPD 2079

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
                  +  D++ECA + G+C +G C NT GSF C C  G+SL                 
Sbjct: 2080 D-----SREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGH 2134

Query: 182  VCGPGVCRNLPGSYVCLCPEGY 203
             CG G C N+ G + C C +G+
Sbjct: 2135 PCGQGTCTNVIGGFECACADGF 2156



 Score =  138 bits (333), Expect = 2e-32
 Identities = 79/211 (37%), Positives = 102/211 (48%), Gaps = 17/211 (8%)

Query: 6    CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC +  S C  G C NT G+YTC CP  Y  V+ G  C D RK+ C+     R  
Sbjct: 1603 CEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCF-----RHY 1657

Query: 65   TETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPG-GPGYQPVLE 121
              TC+  +EL+ + T   CCCS  +G AW   C+ CP P S  Y+ LC    PG+   + 
Sbjct: 1658 NGTCQ--NELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIH 1715

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                +    DIDEC     +CA+G C N  GSF C C AG++  +             R 
Sbjct: 1716 TGKPL----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRE 1771

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGS 210
              C     C N+PGSY C C  GY   P G+
Sbjct: 1772 SPCQQNADCINIPGSYRCKCTRGYKLSPGGA 1802



 Score =  120 bits (290), Expect = 3e-27
 Identities = 65/203 (32%), Positives = 91/203 (44%), Gaps = 16/203 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  C D+DEC++P  C  G C NT+GS+ C+C     + +DG  C D+  ++ CYG ++ 
Sbjct: 567 GHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEK 626

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            S       +   SE      CC +    +G  C  CP   S  ++ LC  G G      
Sbjct: 627 GSCARPFPGTVTKSE-----CCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLG------ 675

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                    DI+ECA    +CA+G C N  GS+ C C  G+   A               
Sbjct: 676 ---ITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732

Query: 181 DVCGPGVCRNLPGSYVCLCPEGY 203
            +C  G C+N PGSY C CP G+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGF 755



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 72/222 (32%), Positives = 95/222 (42%), Gaps = 32/222 (14%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  G C+NT GS+ C C P YE    G     +    C    +   
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYE---SGFMLMKN----CMDVDECAR 1077

Query: 64   GTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPE--------PGSEAYRQL--- 109
                CR     + DG+   C C  G    A G  C+   E        P  +    +   
Sbjct: 1078 DPLLCRGGTCTNTDGSYK-CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAF 1136

Query: 110  -CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPX 167
             C    G+Q   +    V    DI+EC    G C  H  C NT GS+ C+CG G+SL P 
Sbjct: 1137 QCSCHAGFQSTPDRQGCV----DINECRVQNGGCDVH--CINTEGSYRCSCGQGYSLMPD 1190

Query: 168  XXXXXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                         P VC  G C N+PG + CLC +G++A P+
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232



 Score = 99.1 bits (236), Expect = 1e-20
 Identities = 70/214 (32%), Positives = 92/214 (42%), Gaps = 20/214 (9%)

Query: 6    CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            C+DVDEC+    +C  +  C+N  GS++CRC P +  V DG  C+D  +  C  +    S
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECHDLDE--CVSQEHRCS 1333

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQPV 119
                C     L+  G+    C    A  G +C   D C E         C   PG Y+  
Sbjct: 1334 PRGDC-----LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCE 1388

Query: 120  LE----PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E    P        D+DECA    LCA G+C N  G F C C  G+ L           
Sbjct: 1389 CEMGFDPTEDHRACQDVDECA-QGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDIN 1447

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                P  C  GVC N PGSY+C CP+ +   P+G
Sbjct: 1448 ECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 59/160 (36%), Positives = 74/160 (46%), Gaps = 22/160 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC S   C  G C N  GSYTC+C P   L   GT C DS K  C+ K+      
Sbjct: 764 CKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKI------ 816

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-EPGSEAYRQLCPGGPGYQPVLEPPS 124
           +  R    L      + CC ++GAAWG+ C+ C  +P        C  G           
Sbjct: 817 QESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPA-------CARGFARMT------ 863

Query: 125 YVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
             VT  D++EC +  G+C +G C NT GSF C C  G  L
Sbjct: 864 -GVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLML 902



 Score = 89.8 bits (213), Expect = 7e-18
 Identities = 63/215 (29%), Positives = 88/215 (40%), Gaps = 22/215 (10%)

Query: 3    GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVD 60
            G  C D+DEC  S   C +GQC+N  G++ C C   ++   D   C D  + R   G  D
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167

Query: 61   LRS-GTE-----TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
            +    TE     +C     L  DG     C  V     + C+  P    + +    PGG 
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGR---ACADV-----DECEENPRVCDQGHCTNMPGGH 1219

Query: 115  G---YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX-- 169
                Y   +  P  + T  D+DEC  +  +C HG C NT GSFVC C  G+ +       
Sbjct: 1220 RCLCYDGFMATPD-MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGC 1278

Query: 170  XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +      C N+PGS+ C C  G+V
Sbjct: 1279 SDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV 1313



 Score = 86.6 bits (205), Expect = 6e-17
 Identities = 65/219 (29%), Positives = 93/219 (42%), Gaps = 22/219 (10%)

Query: 2    PGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCY 56
            PG  C   +EC+  P  C +G C++T+GSY C C   ++  +D T C D     R+    
Sbjct: 1799 PGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGN 1858

Query: 57   GKVDLRSGTETCR--DSDELSEDGTMA---ACCCSVGAAWG-NYCDPCPEPGSEAYRQLC 110
            G      G+  C       ++ +G       C   VG      +C      GS  +  LC
Sbjct: 1859 GTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHC--LNTAGS--FHCLC 1914

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
              G  ++   +  + V    D +EC +  G C  GTC N  GSF C C  G+ +      
Sbjct: 1915 QDG--FELTADGKNCV----DTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQ-SDHC 1967

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     P++C  G C N PGS+ CLCP G+V   NG
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 67/219 (30%), Positives = 90/219 (41%), Gaps = 21/219 (9%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
            DVDEC+     C +G+CIN+ GS+ C C   Y   +  T C D  +     K      T 
Sbjct: 2363 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPK----PCTF 2418

Query: 67   TCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGGPGYQPVLE 121
             C+++      G+   C C  G      G  C    E  S  +  + LC    G      
Sbjct: 2419 LCKNTK-----GSFL-CSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRC 2472

Query: 122  PPSYVV---TLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
            PP +        D DEC+A  G C AHG C NT GSF C C  G++L             
Sbjct: 2473 PPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532

Query: 178  XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
              P  C  G C+N  G Y C CP+G+      +Q + +N
Sbjct: 2533 DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDEN 2570



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 48/125 (38%), Positives = 60/125 (48%), Gaps = 16/125 (12%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DVDEC++ P  CQ G C+N  GS+ CRCP  + L     AC D R   C+    L  G
Sbjct: 245 CQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSV--LFGG 302

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQLC-------PGGPG 115
               R + +L+   T   CCC  G  W  G   + CP  GS  ++QLC       PG PG
Sbjct: 303 ----RCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPG 358

Query: 116 YQPVL 120
             P L
Sbjct: 359 LFPGL 363



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 63/220 (28%), Positives = 87/220 (39%), Gaps = 27/220 (12%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
            G  C D+DEC S Q +CQ+  C+NT G++TCRCPP +       AC+D+ +         
Sbjct: 2441 GRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGF--TQHHQACFDNDECSAQPGPCG 2497

Query: 56   -YGKVDLRSGTETCRDSDELSEDGTMAAC---CCSVGAAWGNY-CDPCPEPGSEAYRQLC 110
             +G      G+  C    E  +  T+ +    C  V    G + C    +     YR  C
Sbjct: 2498 AHGHCHNTPGSFRC----ECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSC 2553

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
            P G          S      D +ECA     C   +C NT G F C C +G+        
Sbjct: 2554 PQG------FTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607

Query: 171  XXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     R   C    C N PG ++C CP+GY     G
Sbjct: 2608 CQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQG 2646



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 63/210 (30%), Positives = 85/210 (40%), Gaps = 25/210 (11%)

Query: 6    CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCYGKV 59
            C D+DEC   P+ C +  C NT+GS+ C CP  Y L  DG  C D     SR+  C    
Sbjct: 2403 CLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLC 2461

Query: 60   DLRSGTETCRDSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
                G  TCR     ++     AC     C +     G +      PGS  +R  C    
Sbjct: 2462 VNTVGAFTCRCPPGFTQH--HQACFDNDECSAQPGPCGAHGHCHNTPGS--FR--CECHQ 2515

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXX 173
            G+  V    S      D++EC      C HG C N  G + C+C  G++  +        
Sbjct: 2516 GFTLV----SSGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDE 2569

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  CG   CRN  G + C+CP G+
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGF 2599



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 58/167 (34%), Positives = 74/167 (44%), Gaps = 23/167 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-----ARCY-GKV 59
           C DVDEC S   C +G C+N  G+Y CRC P ++      AC D  +       C+ G+ 
Sbjct: 447 CIDVDECTS-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505

Query: 60  DLRSGTE--TCRDSDELSEDGTMAAC---CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
               G+    C    ELS DG        C +        C    E GS  +  LC   P
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVC--LNEDGS--FSCLCK--P 559

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
           G+  +L P  +     DIDEC    G+C +G CTNT GSF C C  G
Sbjct: 560 GF--LLAPGGHY--CMDIDECQT-PGICVNGHCTNTEGSFRCQCLGG 601



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 54/175 (30%), Positives = 65/175 (37%), Gaps = 19/175 (10%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARCYG 57
            G NC D DEC     C  G C N  G + C C   +E        D   C       C  
Sbjct: 2121 GINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDEC-SLNPLLCAF 2179

Query: 58   KVDLRSGTE--TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CP 111
            +     G+   TC     L EDG M   C  V        D C   G E    +    C 
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAM---CRDVDECADGQQD-CHARGMECKNLIGTFACV 2235

Query: 112  GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              PG +P+   P       D +EC A   LC +G C NT GSF C C  G+  +P
Sbjct: 2236 CPPGMRPL---PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSP 2287



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 19/210 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC D +EC +   C  G C+N  GS++C C P + L   G  C D  + +  G     
Sbjct: 526 GKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPG----- 580

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
                C +    + +G+   C C  G A G     C +      R  C G         P
Sbjct: 581 ----ICVNGHCTNTEGSFR-CQCLGGLAVGTDGRVCVDTH---VRSTCYGAIEKGSCARP 632

Query: 123 PSYVVTLADIDECAAHEGL---CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
               VT ++        G    C      N+   F   C +G  L               
Sbjct: 633 FPGTVTKSECCCANPDHGFGEPCQLCPAKNS-AEFQALCSSG--LGITTDGRDINECALD 689

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P+VC  GVC NL GSY C+C  GY A  +G
Sbjct: 690 PEVCANGVCENLRGSYRCVCNLGYEAGASG 719



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 59/187 (31%), Positives = 73/187 (39%), Gaps = 28/187 (14%)

Query: 21  GQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSGTETCRDSDELSEDGT 79
           G+CI   G   C C   +     G  C  D R   C+G+V    G E C+         T
Sbjct: 159 GRCI---GPNRCACVYGFM----GPQCERDYRTGPCFGQV----GPEGCQHQ-LTGLVCT 206

Query: 80  MAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHE 139
            A CC +VG AWG  C+ CP        Q  P   G+ P +    +     D+DEC A  
Sbjct: 207 KALCCATVGRAWGLPCELCPA-------QPHPCRRGFIPNI----HTGACQDVDECQAVP 255

Query: 140 GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR-NLPGSYV-- 196
           GLC  G+C N  GSF C C  G  L+                V   G C  +L G Y   
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRR 315

Query: 197 -CLCPEG 202
            C C  G
Sbjct: 316 QCCCDRG 322



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 26/177 (14%)

Query: 3    GFNCTDVDECKSPQ-SCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            GF C D+DEC S +  C   G C+N  GSY C C   +    DG  C D  +  C   VD
Sbjct: 1316 GFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCED--RDECAENVD 1371

Query: 61   LRSGTETC------RDSDELSEDGT--MAACCCSVGAAWGNYC--DPCPE-PGSEAYRQL 109
            L    +        R   E+  D T    AC      A GN C    C   PG   +R +
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPG--MFRCI 1429

Query: 110  CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
            C G  GY+  L+      T  DI+ECA     C +G C NT GS++C+C   + L P
Sbjct: 1430 CNG--GYE--LDRGGGNCT--DINECADPVN-CINGVCINTPGSYLCSCPQDFELNP 1479



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 61/210 (29%), Positives = 77/210 (36%), Gaps = 19/210 (9%)

Query: 9   VDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCY-GKVDLRS 63
           +D C+     C  G+C+ T  SY C C   Y     G  C D      + C+ G      
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHGDCVNIP 467

Query: 64  GTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           GT  CR         T  AC     C V    G  C       +E   Q C    G++  
Sbjct: 468 GTYHCRCYPGFQATPTRQACVDVDECIVS---GGLCHLGRCVNTEGSFQ-CVCNAGFE-- 521

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
           L P        D +ECA    +C +G C N  GSF C C  G+ LAP             
Sbjct: 522 LSPDGK--NCVDHNECATST-MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQT 578

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P +C  G C N  GS+ C C  G     +G
Sbjct: 579 PGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D+DECA +  LC +G C N+ GS+ C+C  G+                    C  GVCRN
Sbjct: 724 DVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVSGVCRN 782

Query: 191 LPGSYVCLCPEGYVAMPNGSQYLLQNLSTNMRLKIQ 226
           L GSY C C  G    P+G+ + L +      LKIQ
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT-FCLDSTKGTCWLKIQ 817



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX--XXXRP 180
            P  ++T  DIDEC+ +  LCA   C NT GS++CTC AG++L                + 
Sbjct: 2158 PGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQ 2216

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQ 211
            D    G+ C+NL G++ C+CP G   +P   +
Sbjct: 2217 DCHARGMECKNLIGTFACVCPPGMRPLPGSGE 2248



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 131  DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXXXXXXRPDVCGPGVC 188
            DIDEC     LC  GTC NT GSF C C  G+                   P +C  G C
Sbjct: 1028 DIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTC 1087

Query: 189  RNLPGSYVCLCPEGYVAMPNGS 210
             N  GSY C CP G+     G+
Sbjct: 1088 TNTDGSYKCQCPPGHELTAKGT 1109



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 55/211 (26%), Positives = 77/211 (36%), Gaps = 27/211 (12%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +CTDVDEC  +   C  G C N+ GSY+C CPP +    D                  
Sbjct: 719 GKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQD------------------ 760

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE-PGSEAYRQLCPGGPGYQPVL 120
              TE C+D DE      ++  C ++  ++   C P      S  +      G  +  + 
Sbjct: 761 ---TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQ 817

Query: 121 EPPSYV-VTLADI-DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           E    V +  A +  EC A  G      C          C  G++               
Sbjct: 818 ESRCEVNLQGASLRSECCATLGAAWGSPCERC--EIDPACARGFARMTGVTCDDVNECES 875

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            P VC  G C N  GS+ C CPEG +   +G
Sbjct: 876 FPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 127  VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
            +   D DEC+     C  GTCTN  G F C C  G+                 P +C   
Sbjct: 2122 INCVDTDECSVGHP-CGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR 2180

Query: 187  VCRNLPGSYVCLCPEGYVAMPNGS 210
             C N  GSY+C CP GY    +G+
Sbjct: 2181 -CHNTEGSYLCTCPAGYTLREDGA 2203



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCR 189
           D+DEC +    C HG C N  G++ C C  G+   P                +C  G C 
Sbjct: 449 DVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCV 506

Query: 190 NLPGSYVCLCPEGYVAMPNGSQYLLQN 216
           N  GS+ C+C  G+   P+G   +  N
Sbjct: 507 NTEGSFQCVCNAGFELSPDGKNCVDHN 533



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 11/24 (45%), Positives = 15/24 (62%)

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P +C  G C N+ GS+ C CP G+
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGH 278


>AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.
          Length = 2809

 Score =  193 bits (471), Expect = 4e-49
 Identities = 90/209 (43%), Positives = 112/209 (53%), Gaps = 6/209 (2%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G NCTD++EC  P +C  G CINT GSY C CP ++EL   G  C D+R   C+ +   R
Sbjct: 1440 GGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDR 1499

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
             G      S E+    T A+CCCS+G AWGN C+ CP   +  YR LCPGG G+Q    P
Sbjct: 1500 -GDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQ----P 1554

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPD 181
                V L DIDEC    GLC  G C NTFGSF C C  G+ L+                 
Sbjct: 1555 NRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSS 1614

Query: 182  VCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
            +CGPG C N  G+Y C+CP  Y+ +  G+
Sbjct: 1615 ICGPGTCYNTLGNYTCVCPAEYLQVNGGN 1643



 Score =  162 bits (393), Expect = 1e-39
 Identities = 83/205 (40%), Positives = 104/205 (50%), Gaps = 9/205 (4%)

Query: 1    MPGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            M G  C DV+EC+S P  C  G+C+NT GS+ C CP    L + G  C D R   C+   
Sbjct: 862  MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCF--- 918

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
             LR   + C  +  L     M  CCCS+GA WG  C+ CP+P S  +  LCP G G+   
Sbjct: 919  -LRWDEDECGVT--LPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS- 974

Query: 120  LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXX 178
             +  S      D++EC    GLC HGTC NT GSF C C  G++L A             
Sbjct: 975  RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGY 203
             PD+CG G C N PGS+ C C  GY
Sbjct: 1035 SPDLCGQGTCVNTPGSFECECFPGY 1059



 Score =  153 bits (370), Expect = 7e-37
 Identities = 80/209 (38%), Positives = 106/209 (50%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  CTD +EC + P  C  G+C+NT GS+ C C   ++     T C+D R+  C+ +V L
Sbjct: 2247 GEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV-L 2305

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++    CR     SE  T A CCC  G  WG  C+ CP PG+ AYR+LCP G G      
Sbjct: 2306 QT---MCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSG------ 2356

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               Y     D+DEC     LCAHG C N+ GSF C C AG++  A              P
Sbjct: 2357 ---YTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP 2413

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GS++C CP GY+   +G
Sbjct: 2414 KPC-TFLCKNTKGSFLCSCPRGYLLEEDG 2441



 Score =  147 bits (357), Expect = 2e-35
 Identities = 71/202 (35%), Positives = 106/202 (52%), Gaps = 14/202 (6%)

Query: 5    NCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D+DEC + P  C +G C N+ GS+ C CPP + L  +G  C+D+R++ C+ +     
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRF---- 2021

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
              E  + S   + + T   CCCS   G  WG+ C+ CP+ GS A+++LCP G G  P  +
Sbjct: 2022 --EAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPD 2079

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
                  +  D++ECA + G+C +G C NT GSF C C  G+SL                 
Sbjct: 2080 D-----SREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGH 2134

Query: 182  VCGPGVCRNLPGSYVCLCPEGY 203
             CG G C N+ G + C C +G+
Sbjct: 2135 PCGQGTCTNVIGGFECACADGF 2156



 Score =  138 bits (333), Expect = 2e-32
 Identities = 79/211 (37%), Positives = 102/211 (48%), Gaps = 17/211 (8%)

Query: 6    CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC +  S C  G C NT G+YTC CP  Y  V+ G  C D RK+ C+     R  
Sbjct: 1603 CEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCF-----RHY 1657

Query: 65   TETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPG-GPGYQPVLE 121
              TC+  +EL+ + T   CCCS  +G AW   C+ CP P S  Y+ LC    PG+   + 
Sbjct: 1658 NGTCQ--NELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIH 1715

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                +    DIDEC     +CA+G C N  GSF C C AG++  +             R 
Sbjct: 1716 TGKPL----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRE 1771

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGS 210
              C     C N+PGSY C C  GY   P G+
Sbjct: 1772 SPCQQNADCINIPGSYRCKCTRGYKLSPGGA 1802



 Score =  120 bits (290), Expect = 3e-27
 Identities = 65/203 (32%), Positives = 91/203 (44%), Gaps = 16/203 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  C D+DEC++P  C  G C NT+GS+ C+C     + +DG  C D+  ++ CYG ++ 
Sbjct: 567 GHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEK 626

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            S       +   SE      CC +    +G  C  CP   S  ++ LC  G G      
Sbjct: 627 GSCARPFPGTVTKSE-----CCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLG------ 675

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                    DI+ECA    +CA+G C N  GS+ C C  G+   A               
Sbjct: 676 ---ITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732

Query: 181 DVCGPGVCRNLPGSYVCLCPEGY 203
            +C  G C+N PGSY C CP G+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGF 755



 Score = 99.1 bits (236), Expect = 1e-20
 Identities = 70/214 (32%), Positives = 92/214 (42%), Gaps = 20/214 (9%)

Query: 6    CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            C+DVDEC+    +C  +  C+N  GS++CRC P +  V DG  C+D  +  C  +    S
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECHDLDE--CVSQEHRCS 1333

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQPV 119
                C     L+  G+    C    A  G +C   D C E         C   PG Y+  
Sbjct: 1334 PRGDC-----LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCE 1388

Query: 120  LE----PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E    P        D+DECA    LCA G+C N  G F C C  G+ L           
Sbjct: 1389 CEMGFDPTEDHRACQDVDECA-QGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDIN 1447

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                P  C  GVC N PGSY+C CP+ +   P+G
Sbjct: 1448 ECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 59/160 (36%), Positives = 74/160 (46%), Gaps = 22/160 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC S   C  G C N  GSYTC+C P   L   GT C DS K  C+ K+      
Sbjct: 764 CKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKI------ 816

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-EPGSEAYRQLCPGGPGYQPVLEPPS 124
           +  R    L      + CC ++GAAWG+ C+ C  +P        C  G           
Sbjct: 817 QESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPA-------CARGFARMT------ 863

Query: 125 YVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
             VT  D++EC +  G+C +G C NT GSF C C  G  L
Sbjct: 864 -GVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLML 902



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 71/207 (34%), Positives = 93/207 (44%), Gaps = 42/207 (20%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  G C+NT GS+ C C P YE                 G + +++
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYES----------------GFMLMKN 1068

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPP 123
                C D DE + D  +          WG  C      GS  Y+  CP  PG++   +  
Sbjct: 1069 ----CMDVDECARDPLLC---------WGGTCTNTD--GS--YKCQCP--PGHELTAKGT 1109

Query: 124  SYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC 183
            +      DIDEC+  +GLC HG C N  G+F C+C AG+   P            R    
Sbjct: 1110 A----CEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP-DRQGCVDINECRVQNG 1164

Query: 184  GPGV-CRNLPGSYVCLCPEGYVAMPNG 209
            G  V C N  GSY C C +GY  MP+G
Sbjct: 1165 GCDVHCINTEGSYRCSCGQGYSLMPDG 1191



 Score = 89.8 bits (213), Expect = 7e-18
 Identities = 63/215 (29%), Positives = 88/215 (40%), Gaps = 22/215 (10%)

Query: 3    GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVD 60
            G  C D+DEC  S   C +GQC+N  G++ C C   ++   D   C D  + R   G  D
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167

Query: 61   LRS-GTE-----TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
            +    TE     +C     L  DG     C  V     + C+  P    + +    PGG 
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGR---ACADV-----DECEENPRVCDQGHCTNMPGGH 1219

Query: 115  G---YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX-- 169
                Y   +  P  + T  D+DEC  +  +C HG C NT GSFVC C  G+ +       
Sbjct: 1220 RCLCYDGFMATPD-MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGC 1278

Query: 170  XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +      C N+PGS+ C C  G+V
Sbjct: 1279 SDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV 1313



 Score = 86.6 bits (205), Expect = 6e-17
 Identities = 65/219 (29%), Positives = 93/219 (42%), Gaps = 22/219 (10%)

Query: 2    PGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCY 56
            PG  C   +EC+  P  C +G C++T+GSY C C   ++  +D T C D     R+    
Sbjct: 1799 PGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGN 1858

Query: 57   GKVDLRSGTETCR--DSDELSEDGTMA---ACCCSVGAAWG-NYCDPCPEPGSEAYRQLC 110
            G      G+  C       ++ +G       C   VG      +C      GS  +  LC
Sbjct: 1859 GTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHC--LNTAGS--FHCLC 1914

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
              G  ++   +  + V    D +EC +  G C  GTC N  GSF C C  G+ +      
Sbjct: 1915 QDG--FELTADGKNCV----DTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQ-SDHC 1967

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     P++C  G C N PGS+ CLCP G+V   NG
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 67/219 (30%), Positives = 90/219 (41%), Gaps = 21/219 (9%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
            DVDEC+     C +G+CIN+ GS+ C C   Y   +  T C D  +     K      T 
Sbjct: 2363 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPK----PCTF 2418

Query: 67   TCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGGPGYQPVLE 121
             C+++      G+   C C  G      G  C    E  S  +  + LC    G      
Sbjct: 2419 LCKNTK-----GSFL-CSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRC 2472

Query: 122  PPSYVV---TLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
            PP +        D DEC+A  G C AHG C NT GSF C C  G++L             
Sbjct: 2473 PPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532

Query: 178  XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
              P  C  G C+N  G Y C CP+G+      +Q + +N
Sbjct: 2533 DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDEN 2570



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 48/125 (38%), Positives = 60/125 (48%), Gaps = 16/125 (12%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DVDEC++ P  CQ G C+N  GS+ CRCP  + L     AC D R   C+    L  G
Sbjct: 245 CQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSV--LFGG 302

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQLC-------PGGPG 115
               R + +L+   T   CCC  G  W  G   + CP  GS  ++QLC       PG PG
Sbjct: 303 ----RCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPG 358

Query: 116 YQPVL 120
             P L
Sbjct: 359 LFPGL 363



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 63/220 (28%), Positives = 87/220 (39%), Gaps = 27/220 (12%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
            G  C D+DEC S Q +CQ+  C+NT G++TCRCPP +       AC+D+ +         
Sbjct: 2441 GRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGF--TQHHQACFDNDECSAQPGPCG 2497

Query: 56   -YGKVDLRSGTETCRDSDELSEDGTMAAC---CCSVGAAWGNY-CDPCPEPGSEAYRQLC 110
             +G      G+  C    E  +  T+ +    C  V    G + C    +     YR  C
Sbjct: 2498 AHGHCHNTPGSFRC----ECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSC 2553

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
            P G          S      D +ECA     C   +C NT G F C C +G+        
Sbjct: 2554 PQG------FTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607

Query: 171  XXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     R   C    C N PG ++C CP+GY     G
Sbjct: 2608 CQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQG 2646



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 63/210 (30%), Positives = 85/210 (40%), Gaps = 25/210 (11%)

Query: 6    CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCYGKV 59
            C D+DEC   P+ C +  C NT+GS+ C CP  Y L  DG  C D     SR+  C    
Sbjct: 2403 CLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLC 2461

Query: 60   DLRSGTETCRDSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
                G  TCR     ++     AC     C +     G +      PGS  +R  C    
Sbjct: 2462 VNTVGAFTCRCPPGFTQH--HQACFDNDECSAQPGPCGAHGHCHNTPGS--FR--CECHQ 2515

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXX 173
            G+  V    S      D++EC      C HG C N  G + C+C  G++  +        
Sbjct: 2516 GFTLV----SSGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDE 2569

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  CG   CRN  G + C+CP G+
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGF 2599



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 58/167 (34%), Positives = 74/167 (44%), Gaps = 23/167 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-----ARCY-GKV 59
           C DVDEC S   C +G C+N  G+Y CRC P ++      AC D  +       C+ G+ 
Sbjct: 447 CIDVDECTS-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505

Query: 60  DLRSGTE--TCRDSDELSEDGTMAAC---CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
               G+    C    ELS DG        C +        C    E GS  +  LC   P
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVC--LNEDGS--FSCLCK--P 559

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
           G+  +L P  +     DIDEC    G+C +G CTNT GSF C C  G
Sbjct: 560 GF--LLAPGGHY--CMDIDECQT-PGICVNGHCTNTEGSFRCQCLGG 601



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 54/175 (30%), Positives = 65/175 (37%), Gaps = 19/175 (10%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARCYG 57
            G NC D DEC     C  G C N  G + C C   +E        D   C       C  
Sbjct: 2121 GINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDEC-SLNPLLCAF 2179

Query: 58   KVDLRSGTE--TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CP 111
            +     G+   TC     L EDG M   C  V        D C   G E    +    C 
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAM---CRDVDECADGQQD-CHARGMECKNLIGTFACV 2235

Query: 112  GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              PG +P+   P       D +EC A   LC +G C NT GSF C C  G+  +P
Sbjct: 2236 CPPGMRPL---PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSP 2287



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 19/210 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC D +EC +   C  G C+N  GS++C C P + L   G  C D  + +  G     
Sbjct: 526 GKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPG----- 580

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
                C +    + +G+   C C  G A G     C +      R  C G         P
Sbjct: 581 ----ICVNGHCTNTEGSFR-CQCLGGLAVGTDGRVCVDTH---VRSTCYGAIEKGSCARP 632

Query: 123 PSYVVTLADIDECAAHEGL---CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
               VT ++        G    C      N+   F   C +G  L               
Sbjct: 633 FPGTVTKSECCCANPDHGFGEPCQLCPAKNS-AEFQALCSSG--LGITTDGRDINECALD 689

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P+VC  GVC NL GSY C+C  GY A  +G
Sbjct: 690 PEVCANGVCENLRGSYRCVCNLGYEAGASG 719



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 59/187 (31%), Positives = 73/187 (39%), Gaps = 28/187 (14%)

Query: 21  GQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSGTETCRDSDELSEDGT 79
           G+CI   G   C C   +     G  C  D R   C+G+V    G E C+         T
Sbjct: 159 GRCI---GPNRCACVYGFM----GPQCERDYRTGPCFGQV----GPEGCQHQ-LTGLVCT 206

Query: 80  MAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHE 139
            A CC +VG AWG  C+ CP        Q  P   G+ P +    +     D+DEC A  
Sbjct: 207 KALCCATVGRAWGLPCELCPA-------QPHPCRRGFIPNI----HTGACQDVDECQAVP 255

Query: 140 GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR-NLPGSYV-- 196
           GLC  G+C N  GSF C C  G  L+                V   G C  +L G Y   
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRR 315

Query: 197 -CLCPEG 202
            C C  G
Sbjct: 316 QCCCDRG 322



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 26/177 (14%)

Query: 3    GFNCTDVDECKSPQ-SCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            GF C D+DEC S +  C   G C+N  GSY C C   +    DG  C D  +  C   VD
Sbjct: 1316 GFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCED--RDECAENVD 1371

Query: 61   LRSGTETC------RDSDELSEDGT--MAACCCSVGAAWGNYC--DPCPE-PGSEAYRQL 109
            L    +        R   E+  D T    AC      A GN C    C   PG   +R +
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPG--MFRCI 1429

Query: 110  CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
            C G  GY+  L+      T  DI+ECA     C +G C NT GS++C+C   + L P
Sbjct: 1430 CNG--GYE--LDRGGGNCT--DINECADPVN-CINGVCINTPGSYLCSCPQDFELNP 1479



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 61/210 (29%), Positives = 77/210 (36%), Gaps = 19/210 (9%)

Query: 9   VDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCY-GKVDLRS 63
           +D C+     C  G+C+ T  SY C C   Y     G  C D      + C+ G      
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHGDCVNIP 467

Query: 64  GTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           GT  CR         T  AC     C V    G  C       +E   Q C    G++  
Sbjct: 468 GTYHCRCYPGFQATPTRQACVDVDECIVS---GGLCHLGRCVNTEGSFQ-CVCNAGFE-- 521

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
           L P        D +ECA    +C +G C N  GSF C C  G+ LAP             
Sbjct: 522 LSPDGK--NCVDHNECATST-MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQT 578

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P +C  G C N  GS+ C C  G     +G
Sbjct: 579 PGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D+DECA +  LC +G C N+ GS+ C+C  G+                    C  GVCRN
Sbjct: 724 DVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVSGVCRN 782

Query: 191 LPGSYVCLCPEGYVAMPNGSQYLLQNLSTNMRLKIQ 226
           L GSY C C  G    P+G+ + L +      LKIQ
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT-FCLDSTKGTCWLKIQ 817



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX--XXXRP 180
            P  ++T  DIDEC+ +  LCA   C NT GS++CTC AG++L                + 
Sbjct: 2158 PGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQ 2216

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQ 211
            D    G+ C+NL G++ C+CP G   +P   +
Sbjct: 2217 DCHARGMECKNLIGTFACVCPPGMRPLPGSGE 2248



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 131  DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXXXXXXRPDVCGPGVC 188
            DIDEC     LC  GTC NT GSF C C  G+                   P +C  G C
Sbjct: 1028 DIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCWGGTC 1087

Query: 189  RNLPGSYVCLCPEGYVAMPNGS 210
             N  GSY C CP G+     G+
Sbjct: 1088 TNTDGSYKCQCPPGHELTAKGT 1109



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 55/211 (26%), Positives = 77/211 (36%), Gaps = 27/211 (12%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +CTDVDEC  +   C  G C N+ GSY+C CPP +    D                  
Sbjct: 719 GKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQD------------------ 760

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE-PGSEAYRQLCPGGPGYQPVL 120
              TE C+D DE      ++  C ++  ++   C P      S  +      G  +  + 
Sbjct: 761 ---TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQ 817

Query: 121 EPPSYV-VTLADI-DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           E    V +  A +  EC A  G      C          C  G++               
Sbjct: 818 ESRCEVNLQGASLRSECCATLGAAWGSPCERC--EIDPACARGFARMTGVTCDDVNECES 875

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            P VC  G C N  GS+ C CPEG +   +G
Sbjct: 876 FPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 127  VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
            +   D DEC+     C  GTCTN  G F C C  G+                 P +C   
Sbjct: 2122 INCVDTDECSVGHP-CGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR 2180

Query: 187  VCRNLPGSYVCLCPEGYVAMPNGS 210
             C N  GSY+C CP GY    +G+
Sbjct: 2181 -CHNTEGSYLCTCPAGYTLREDGA 2203



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCR 189
           D+DEC +    C HG C N  G++ C C  G+   P                +C  G C 
Sbjct: 449 DVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCV 506

Query: 190 NLPGSYVCLCPEGYVAMPNGSQYLLQN 216
           N  GS+ C+C  G+   P+G   +  N
Sbjct: 507 NTEGSFQCVCNAGFELSPDGKNCVDHN 533



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 11/24 (45%), Positives = 15/24 (62%)

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P +C  G C N+ GS+ C CP G+
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGH 278


>AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.
          Length = 2809

 Score =  193 bits (471), Expect = 4e-49
 Identities = 90/209 (43%), Positives = 112/209 (53%), Gaps = 6/209 (2%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G NCTD++EC  P +C  G CINT GSY C CP ++EL   G  C D+R   C+ +   R
Sbjct: 1440 GGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDR 1499

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
             G      S E+    T A+CCCS+G AWGN C+ CP   +  YR LCPGG G+Q    P
Sbjct: 1500 -GDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQ----P 1554

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPD 181
                V L DIDEC    GLC  G C NTFGSF C C  G+ L+                 
Sbjct: 1555 NRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSS 1614

Query: 182  VCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
            +CGPG C N  G+Y C+CP  Y+ +  G+
Sbjct: 1615 ICGPGTCYNTLGNYTCVCPAEYLQVNGGN 1643



 Score =  161 bits (391), Expect = 2e-39
 Identities = 83/205 (40%), Positives = 104/205 (50%), Gaps = 9/205 (4%)

Query: 1    MPGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            M G  C DV+EC+S P  C  G+C+NT GS+ C CP    L + G  C D R   C+   
Sbjct: 862  MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCF--- 918

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
             LR   + C  +  L     M  CCCS+GA WG  C+ CP+P S  +  LCP G G+   
Sbjct: 919  -LRWDEDECGVT--LPGKYRMDFCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS- 974

Query: 120  LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXX 178
             +  S      D++EC    GLC HGTC NT GSF C C  G++L A             
Sbjct: 975  RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGY 203
             PD+CG G C N PGS+ C C  GY
Sbjct: 1035 SPDLCGQGTCVNTPGSFECECFPGY 1059



 Score =  153 bits (370), Expect = 7e-37
 Identities = 80/209 (38%), Positives = 106/209 (50%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  CTD +EC + P  C  G+C+NT GS+ C C   ++     T C+D R+  C+ +V L
Sbjct: 2247 GEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV-L 2305

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++    CR     SE  T A CCC  G  WG  C+ CP PG+ AYR+LCP G G      
Sbjct: 2306 QT---MCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSG------ 2356

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               Y     D+DEC     LCAHG C N+ GSF C C AG++  A              P
Sbjct: 2357 ---YTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP 2413

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GS++C CP GY+   +G
Sbjct: 2414 KPC-TFLCKNTKGSFLCSCPRGYLLEEDG 2441



 Score =  147 bits (357), Expect = 2e-35
 Identities = 71/202 (35%), Positives = 106/202 (52%), Gaps = 14/202 (6%)

Query: 5    NCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D+DEC + P  C +G C N+ GS+ C CPP + L  +G  C+D+R++ C+ +     
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRF---- 2021

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
              E  + S   + + T   CCCS   G  WG+ C+ CP+ GS A+++LCP G G  P  +
Sbjct: 2022 --EAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPD 2079

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
                  +  D++ECA + G+C +G C NT GSF C C  G+SL                 
Sbjct: 2080 D-----SREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGH 2134

Query: 182  VCGPGVCRNLPGSYVCLCPEGY 203
             CG G C N+ G + C C +G+
Sbjct: 2135 PCGQGTCTNVIGGFECACADGF 2156



 Score =  138 bits (333), Expect = 2e-32
 Identities = 79/211 (37%), Positives = 102/211 (48%), Gaps = 17/211 (8%)

Query: 6    CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC +  S C  G C NT G+YTC CP  Y  V+ G  C D RK+ C+     R  
Sbjct: 1603 CEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCF-----RHY 1657

Query: 65   TETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPG-GPGYQPVLE 121
              TC+  +EL+ + T   CCCS  +G AW   C+ CP P S  Y+ LC    PG+   + 
Sbjct: 1658 NGTCQ--NELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIH 1715

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                +    DIDEC     +CA+G C N  GSF C C AG++  +             R 
Sbjct: 1716 TGKPL----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRE 1771

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGS 210
              C     C N+PGSY C C  GY   P G+
Sbjct: 1772 SPCQQNADCINIPGSYRCKCTRGYKLSPGGA 1802



 Score =  120 bits (290), Expect = 3e-27
 Identities = 65/203 (32%), Positives = 91/203 (44%), Gaps = 16/203 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  C D+DEC++P  C  G C NT+GS+ C+C     + +DG  C D+  ++ CYG ++ 
Sbjct: 567 GHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEK 626

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            S       +   SE      CC +    +G  C  CP   S  ++ LC  G G      
Sbjct: 627 GSCARPFPGTVTKSE-----CCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLG------ 675

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                    DI+ECA    +CA+G C N  GS+ C C  G+   A               
Sbjct: 676 ---ITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732

Query: 181 DVCGPGVCRNLPGSYVCLCPEGY 203
            +C  G C+N PGSY C CP G+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGF 755



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 72/222 (32%), Positives = 95/222 (42%), Gaps = 32/222 (14%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  G C+NT GS+ C C P YE    G     +    C    +   
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYE---SGFMLMKN----CMDVDECAR 1077

Query: 64   GTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPE--------PGSEAYRQL--- 109
                CR     + DG+   C C  G    A G  C+   E        P  +    +   
Sbjct: 1078 DPLLCRGGTCTNTDGSYK-CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAF 1136

Query: 110  -CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPX 167
             C    G+Q   +    V    DI+EC    G C  H  C NT GS+ C+CG G+SL P 
Sbjct: 1137 QCSCHAGFQSTPDRQGCV----DINECRVQNGGCDVH--CINTEGSYRCSCGQGYSLMPD 1190

Query: 168  XXXXXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                         P VC  G C N+PG + CLC +G++A P+
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232



 Score = 99.1 bits (236), Expect = 1e-20
 Identities = 70/214 (32%), Positives = 92/214 (42%), Gaps = 20/214 (9%)

Query: 6    CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            C+DVDEC+    +C  +  C+N  GS++CRC P +  V DG  C+D  +  C  +    S
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECHDLDE--CVSQEHRCS 1333

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQPV 119
                C     L+  G+    C    A  G +C   D C E         C   PG Y+  
Sbjct: 1334 PRGDC-----LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCE 1388

Query: 120  LE----PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E    P        D+DECA    LCA G+C N  G F C C  G+ L           
Sbjct: 1389 CEMGFDPTEDHRACQDVDECA-QGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDIN 1447

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                P  C  GVC N PGSY+C CP+ +   P+G
Sbjct: 1448 ECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 59/160 (36%), Positives = 74/160 (46%), Gaps = 22/160 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC S   C  G C N  GSYTC+C P   L   GT C DS K  C+ K+      
Sbjct: 764 CKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKI------ 816

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-EPGSEAYRQLCPGGPGYQPVLEPPS 124
           +  R    L      + CC ++GAAWG+ C+ C  +P        C  G           
Sbjct: 817 QESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPA-------CARGFARMT------ 863

Query: 125 YVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
             VT  D++EC +  G+C +G C NT GSF C C  G  L
Sbjct: 864 -GVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLML 902



 Score = 89.8 bits (213), Expect = 7e-18
 Identities = 63/215 (29%), Positives = 88/215 (40%), Gaps = 22/215 (10%)

Query: 3    GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVD 60
            G  C D+DEC  S   C +GQC+N  G++ C C   ++   D   C D  + R   G  D
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167

Query: 61   LRS-GTE-----TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
            +    TE     +C     L  DG     C  V     + C+  P    + +    PGG 
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGR---ACADV-----DECEENPRVCDQGHCTNMPGGH 1219

Query: 115  G---YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX-- 169
                Y   +  P  + T  D+DEC  +  +C HG C NT GSFVC C  G+ +       
Sbjct: 1220 RCLCYDGFMATPD-MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGC 1278

Query: 170  XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +      C N+PGS+ C C  G+V
Sbjct: 1279 SDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV 1313



 Score = 86.6 bits (205), Expect = 6e-17
 Identities = 65/219 (29%), Positives = 93/219 (42%), Gaps = 22/219 (10%)

Query: 2    PGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCY 56
            PG  C   +EC+  P  C +G C++T+GSY C C   ++  +D T C D     R+    
Sbjct: 1799 PGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGN 1858

Query: 57   GKVDLRSGTETCR--DSDELSEDGTMA---ACCCSVGAAWG-NYCDPCPEPGSEAYRQLC 110
            G      G+  C       ++ +G       C   VG      +C      GS  +  LC
Sbjct: 1859 GTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHC--LNTAGS--FHCLC 1914

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
              G  ++   +  + V    D +EC +  G C  GTC N  GSF C C  G+ +      
Sbjct: 1915 QDG--FELTADGKNCV----DTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQ-SDHC 1967

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     P++C  G C N PGS+ CLCP G+V   NG
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 67/219 (30%), Positives = 90/219 (41%), Gaps = 21/219 (9%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
            DVDEC+     C +G+CIN+ GS+ C C   Y   +  T C D  +     K      T 
Sbjct: 2363 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPK----PCTF 2418

Query: 67   TCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGGPGYQPVLE 121
             C+++      G+   C C  G      G  C    E  S  +  + LC    G      
Sbjct: 2419 LCKNTK-----GSFL-CSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRC 2472

Query: 122  PPSYVV---TLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
            PP +        D DEC+A  G C AHG C NT GSF C C  G++L             
Sbjct: 2473 PPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532

Query: 178  XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
              P  C  G C+N  G Y C CP+G+      +Q + +N
Sbjct: 2533 DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDEN 2570



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 48/125 (38%), Positives = 60/125 (48%), Gaps = 16/125 (12%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DVDEC++ P  CQ G C+N  GS+ CRCP  + L     AC D R   C+    L  G
Sbjct: 245 CQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSV--LFGG 302

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQLC-------PGGPG 115
               R + +L+   T   CCC  G  W  G   + CP  GS  ++QLC       PG PG
Sbjct: 303 ----RCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPG 358

Query: 116 YQPVL 120
             P L
Sbjct: 359 LFPGL 363



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 63/220 (28%), Positives = 87/220 (39%), Gaps = 27/220 (12%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
            G  C D+DEC S Q +CQ+  C+NT G++TCRCPP +       AC+D+ +         
Sbjct: 2441 GRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGF--TQHHQACFDNDECSAQPGPCG 2497

Query: 56   -YGKVDLRSGTETCRDSDELSEDGTMAAC---CCSVGAAWGNY-CDPCPEPGSEAYRQLC 110
             +G      G+  C    E  +  T+ +    C  V    G + C    +     YR  C
Sbjct: 2498 AHGHCHNTPGSFRC----ECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSC 2553

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
            P G          S      D +ECA     C   +C NT G F C C +G+        
Sbjct: 2554 PQG------FTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607

Query: 171  XXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     R   C    C N PG ++C CP+GY     G
Sbjct: 2608 CQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQG 2646



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 63/210 (30%), Positives = 85/210 (40%), Gaps = 25/210 (11%)

Query: 6    CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCYGKV 59
            C D+DEC   P+ C +  C NT+GS+ C CP  Y L  DG  C D     SR+  C    
Sbjct: 2403 CLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLC 2461

Query: 60   DLRSGTETCRDSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
                G  TCR     ++     AC     C +     G +      PGS  +R  C    
Sbjct: 2462 VNTVGAFTCRCPPGFTQH--HQACFDNDECSAQPGPCGAHGHCHNTPGS--FR--CECHQ 2515

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXX 173
            G+  V    S      D++EC      C HG C N  G + C+C  G++  +        
Sbjct: 2516 GFTLV----SSGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDE 2569

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  CG   CRN  G + C+CP G+
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGF 2599



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 58/167 (34%), Positives = 74/167 (44%), Gaps = 23/167 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-----ARCY-GKV 59
           C DVDEC S   C +G C+N  G+Y CRC P ++      AC D  +       C+ G+ 
Sbjct: 447 CIDVDECTS-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505

Query: 60  DLRSGTE--TCRDSDELSEDGTMAAC---CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
               G+    C    ELS DG        C +        C    E GS  +  LC   P
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVC--LNEDGS--FSCLCK--P 559

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
           G+  +L P  +     DIDEC    G+C +G CTNT GSF C C  G
Sbjct: 560 GF--LLAPGGHY--CMDIDECQT-PGICVNGHCTNTEGSFRCQCLGG 601



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 54/175 (30%), Positives = 65/175 (37%), Gaps = 19/175 (10%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARCYG 57
            G NC D DEC     C  G C N  G + C C   +E        D   C       C  
Sbjct: 2121 GINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDEC-SLNPLLCAF 2179

Query: 58   KVDLRSGTE--TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CP 111
            +     G+   TC     L EDG M   C  V        D C   G E    +    C 
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAM---CRDVDECADGQQD-CHARGMECKNLIGTFACV 2235

Query: 112  GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              PG +P+   P       D +EC A   LC +G C NT GSF C C  G+  +P
Sbjct: 2236 CPPGMRPL---PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSP 2287



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 19/210 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC D +EC +   C  G C+N  GS++C C P + L   G  C D  + +  G     
Sbjct: 526 GKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPG----- 580

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
                C +    + +G+   C C  G A G     C +      R  C G         P
Sbjct: 581 ----ICVNGHCTNTEGSFR-CQCLGGLAVGTDGRVCVDTH---VRSTCYGAIEKGSCARP 632

Query: 123 PSYVVTLADIDECAAHEGL---CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
               VT ++        G    C      N+   F   C +G  L               
Sbjct: 633 FPGTVTKSECCCANPDHGFGEPCQLCPAKNS-AEFQALCSSG--LGITTDGRDINECALD 689

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P+VC  GVC NL GSY C+C  GY A  +G
Sbjct: 690 PEVCANGVCENLRGSYRCVCNLGYEAGASG 719



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 59/187 (31%), Positives = 73/187 (39%), Gaps = 28/187 (14%)

Query: 21  GQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSGTETCRDSDELSEDGT 79
           G+CI   G   C C   +     G  C  D R   C+G+V    G E C+         T
Sbjct: 159 GRCI---GPNRCACVYGFM----GPQCERDYRTGPCFGQV----GPEGCQHQ-LTGLVCT 206

Query: 80  MAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHE 139
            A CC +VG AWG  C+ CP        Q  P   G+ P +    +     D+DEC A  
Sbjct: 207 KALCCATVGRAWGLPCELCPA-------QPHPCRRGFIPNI----HTGACQDVDECQAVP 255

Query: 140 GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR-NLPGSYV-- 196
           GLC  G+C N  GSF C C  G  L+                V   G C  +L G Y   
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRR 315

Query: 197 -CLCPEG 202
            C C  G
Sbjct: 316 QCCCDRG 322



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 26/177 (14%)

Query: 3    GFNCTDVDECKSPQ-SCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            GF C D+DEC S +  C   G C+N  GSY C C   +    DG  C D  +  C   VD
Sbjct: 1316 GFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCED--RDECAENVD 1371

Query: 61   LRSGTETC------RDSDELSEDGT--MAACCCSVGAAWGNYC--DPCPE-PGSEAYRQL 109
            L    +        R   E+  D T    AC      A GN C    C   PG   +R +
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPG--MFRCI 1429

Query: 110  CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
            C G  GY+  L+      T  DI+ECA     C +G C NT GS++C+C   + L P
Sbjct: 1430 CNG--GYE--LDRGGGNCT--DINECADPVN-CINGVCINTPGSYLCSCPQDFELNP 1479



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 61/210 (29%), Positives = 77/210 (36%), Gaps = 19/210 (9%)

Query: 9   VDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCY-GKVDLRS 63
           +D C+     C  G+C+ T  SY C C   Y     G  C D      + C+ G      
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHGDCVNIP 467

Query: 64  GTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           GT  CR         T  AC     C V    G  C       +E   Q C    G++  
Sbjct: 468 GTYHCRCYPGFQATPTRQACVDVDECIVS---GGLCHLGRCVNTEGSFQ-CVCNAGFE-- 521

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
           L P        D +ECA    +C +G C N  GSF C C  G+ LAP             
Sbjct: 522 LSPDGK--NCVDHNECATST-MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQT 578

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P +C  G C N  GS+ C C  G     +G
Sbjct: 579 PGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D+DECA +  LC +G C N+ GS+ C+C  G+                    C  GVCRN
Sbjct: 724 DVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVSGVCRN 782

Query: 191 LPGSYVCLCPEGYVAMPNGSQYLLQNLSTNMRLKIQ 226
           L GSY C C  G    P+G+ + L +      LKIQ
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT-FCLDSTKGTCWLKIQ 817



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX--XXXRP 180
            P  ++T  DIDEC+ +  LCA   C NT GS++CTC AG++L                + 
Sbjct: 2158 PGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQ 2216

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQ 211
            D    G+ C+NL G++ C+CP G   +P   +
Sbjct: 2217 DCHARGMECKNLIGTFACVCPPGMRPLPGSGE 2248



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 131  DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXXXXXXRPDVCGPGVC 188
            DIDEC     LC  GTC NT GSF C C  G+                   P +C  G C
Sbjct: 1028 DIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTC 1087

Query: 189  RNLPGSYVCLCPEGYVAMPNGS 210
             N  GSY C CP G+     G+
Sbjct: 1088 TNTDGSYKCQCPPGHELTAKGT 1109



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 55/211 (26%), Positives = 77/211 (36%), Gaps = 27/211 (12%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +CTDVDEC  +   C  G C N+ GSY+C CPP +    D                  
Sbjct: 719 GKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQD------------------ 760

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE-PGSEAYRQLCPGGPGYQPVL 120
              TE C+D DE      ++  C ++  ++   C P      S  +      G  +  + 
Sbjct: 761 ---TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQ 817

Query: 121 EPPSYV-VTLADI-DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           E    V +  A +  EC A  G      C          C  G++               
Sbjct: 818 ESRCEVNLQGASLRSECCATLGAAWGSPCERC--EIDPACARGFARMTGVTCDDVNECES 875

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            P VC  G C N  GS+ C CPEG +   +G
Sbjct: 876 FPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 127  VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
            +   D DEC+     C  GTCTN  G F C C  G+                 P +C   
Sbjct: 2122 INCVDTDECSVGHP-CGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR 2180

Query: 187  VCRNLPGSYVCLCPEGYVAMPNGS 210
             C N  GSY+C CP GY    +G+
Sbjct: 2181 -CHNTEGSYLCTCPAGYTLREDGA 2203



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCR 189
           D+DEC +    C HG C N  G++ C C  G+   P                +C  G C 
Sbjct: 449 DVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCV 506

Query: 190 NLPGSYVCLCPEGYVAMPNGSQYLLQN 216
           N  GS+ C+C  G+   P+G   +  N
Sbjct: 507 NTEGSFQCVCNAGFELSPDGKNCVDHN 533



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 11/24 (45%), Positives = 15/24 (62%)

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P +C  G C N+ GS+ C CP G+
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGH 278


>AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.
          Length = 2809

 Score =  193 bits (471), Expect = 4e-49
 Identities = 90/209 (43%), Positives = 112/209 (53%), Gaps = 6/209 (2%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G NCTD++EC  P +C  G CINT GSY C CP ++EL   G  C D+R   C+ +   R
Sbjct: 1440 GGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDR 1499

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
             G      S E+    T A+CCCS+G AWGN C+ CP   +  YR LCPGG G+Q    P
Sbjct: 1500 -GDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQ----P 1554

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPD 181
                V L DIDEC    GLC  G C NTFGSF C C  G+ L+                 
Sbjct: 1555 NRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSS 1614

Query: 182  VCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
            +CGPG C N  G+Y C+CP  Y+ +  G+
Sbjct: 1615 ICGPGTCYNTLGNYTCVCPAEYLQVNGGN 1643



 Score =  162 bits (393), Expect = 1e-39
 Identities = 83/205 (40%), Positives = 104/205 (50%), Gaps = 9/205 (4%)

Query: 1    MPGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            M G  C DV+EC+S P  C  G+C+NT GS+ C CP    L + G  C D R   C+   
Sbjct: 862  MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCF--- 918

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
             LR   + C  +  L     M  CCCS+GA WG  C+ CP+P S  +  LCP G G+   
Sbjct: 919  -LRWDEDECGVT--LPGKYLMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS- 974

Query: 120  LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXX 178
             +  S      D++EC    GLC HGTC NT GSF C C  G++L A             
Sbjct: 975  RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGY 203
             PD+CG G C N PGS+ C C  GY
Sbjct: 1035 SPDLCGQGTCVNTPGSFECECFPGY 1059



 Score =  153 bits (370), Expect = 7e-37
 Identities = 80/209 (38%), Positives = 106/209 (50%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  CTD +EC + P  C  G+C+NT GS+ C C   ++     T C+D R+  C+ +V L
Sbjct: 2247 GEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV-L 2305

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++    CR     SE  T A CCC  G  WG  C+ CP PG+ AYR+LCP G G      
Sbjct: 2306 QT---MCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSG------ 2356

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               Y     D+DEC     LCAHG C N+ GSF C C AG++  A              P
Sbjct: 2357 ---YTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP 2413

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GS++C CP GY+   +G
Sbjct: 2414 KPC-TFLCKNTKGSFLCSCPRGYLLEEDG 2441



 Score =  147 bits (357), Expect = 2e-35
 Identities = 71/202 (35%), Positives = 106/202 (52%), Gaps = 14/202 (6%)

Query: 5    NCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D+DEC + P  C +G C N+ GS+ C CPP + L  +G  C+D+R++ C+ +     
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRF---- 2021

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
              E  + S   + + T   CCCS   G  WG+ C+ CP+ GS A+++LCP G G  P  +
Sbjct: 2022 --EAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPD 2079

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
                  +  D++ECA + G+C +G C NT GSF C C  G+SL                 
Sbjct: 2080 D-----SREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGH 2134

Query: 182  VCGPGVCRNLPGSYVCLCPEGY 203
             CG G C N+ G + C C +G+
Sbjct: 2135 PCGQGTCTNVIGGFECACADGF 2156



 Score =  138 bits (333), Expect = 2e-32
 Identities = 79/211 (37%), Positives = 102/211 (48%), Gaps = 17/211 (8%)

Query: 6    CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC +  S C  G C NT G+YTC CP  Y  V+ G  C D RK+ C+     R  
Sbjct: 1603 CEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCF-----RHY 1657

Query: 65   TETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPG-GPGYQPVLE 121
              TC+  +EL+ + T   CCCS  +G AW   C+ CP P S  Y+ LC    PG+   + 
Sbjct: 1658 NGTCQ--NELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIH 1715

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                +    DIDEC     +CA+G C N  GSF C C AG++  +             R 
Sbjct: 1716 TGKPL----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRE 1771

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGS 210
              C     C N+PGSY C C  GY   P G+
Sbjct: 1772 SPCQQNADCINIPGSYRCKCTRGYKLSPGGA 1802



 Score =  120 bits (290), Expect = 3e-27
 Identities = 65/203 (32%), Positives = 91/203 (44%), Gaps = 16/203 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  C D+DEC++P  C  G C NT+GS+ C+C     + +DG  C D+  ++ CYG ++ 
Sbjct: 567 GHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEK 626

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            S       +   SE      CC +    +G  C  CP   S  ++ LC  G G      
Sbjct: 627 GSCARPFPGTVTKSE-----CCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLG------ 675

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                    DI+ECA    +CA+G C N  GS+ C C  G+   A               
Sbjct: 676 ---ITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732

Query: 181 DVCGPGVCRNLPGSYVCLCPEGY 203
            +C  G C+N PGSY C CP G+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGF 755



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 72/222 (32%), Positives = 95/222 (42%), Gaps = 32/222 (14%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  G C+NT GS+ C C P YE    G     +    C    +   
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYE---SGFMLMKN----CMDVDECAR 1077

Query: 64   GTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPE--------PGSEAYRQL--- 109
                CR     + DG+   C C  G    A G  C+   E        P  +    +   
Sbjct: 1078 DPLLCRGGTCTNTDGSYK-CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAF 1136

Query: 110  -CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPX 167
             C    G+Q   +    V    DI+EC    G C  H  C NT GS+ C+CG G+SL P 
Sbjct: 1137 QCSCHAGFQSTPDRQGCV----DINECRVQNGGCDVH--CINTEGSYRCSCGQGYSLMPD 1190

Query: 168  XXXXXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                         P VC  G C N+PG + CLC +G++A P+
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232



 Score = 99.1 bits (236), Expect = 1e-20
 Identities = 70/214 (32%), Positives = 92/214 (42%), Gaps = 20/214 (9%)

Query: 6    CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            C+DVDEC+    +C  +  C+N  GS++CRC P +  V DG  C+D  +  C  +    S
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECHDLDE--CVSQEHRCS 1333

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQPV 119
                C     L+  G+    C    A  G +C   D C E         C   PG Y+  
Sbjct: 1334 PRGDC-----LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCE 1388

Query: 120  LE----PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E    P        D+DECA    LCA G+C N  G F C C  G+ L           
Sbjct: 1389 CEMGFDPTEDHRACQDVDECA-QGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDIN 1447

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                P  C  GVC N PGSY+C CP+ +   P+G
Sbjct: 1448 ECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 59/160 (36%), Positives = 74/160 (46%), Gaps = 22/160 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC S   C  G C N  GSYTC+C P   L   GT C DS K  C+ K+      
Sbjct: 764 CKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKI------ 816

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-EPGSEAYRQLCPGGPGYQPVLEPPS 124
           +  R    L      + CC ++GAAWG+ C+ C  +P        C  G           
Sbjct: 817 QESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPA-------CARGFARMT------ 863

Query: 125 YVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
             VT  D++EC +  G+C +G C NT GSF C C  G  L
Sbjct: 864 -GVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLML 902



 Score = 89.8 bits (213), Expect = 7e-18
 Identities = 63/215 (29%), Positives = 88/215 (40%), Gaps = 22/215 (10%)

Query: 3    GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVD 60
            G  C D+DEC  S   C +GQC+N  G++ C C   ++   D   C D  + R   G  D
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167

Query: 61   LRS-GTE-----TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
            +    TE     +C     L  DG     C  V     + C+  P    + +    PGG 
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGR---ACADV-----DECEENPRVCDQGHCTNMPGGH 1219

Query: 115  G---YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX-- 169
                Y   +  P  + T  D+DEC  +  +C HG C NT GSFVC C  G+ +       
Sbjct: 1220 RCLCYDGFMATPD-MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGC 1278

Query: 170  XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +      C N+PGS+ C C  G+V
Sbjct: 1279 SDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV 1313



 Score = 86.6 bits (205), Expect = 6e-17
 Identities = 65/219 (29%), Positives = 93/219 (42%), Gaps = 22/219 (10%)

Query: 2    PGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCY 56
            PG  C   +EC+  P  C +G C++T+GSY C C   ++  +D T C D     R+    
Sbjct: 1799 PGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGN 1858

Query: 57   GKVDLRSGTETCR--DSDELSEDGTMA---ACCCSVGAAWG-NYCDPCPEPGSEAYRQLC 110
            G      G+  C       ++ +G       C   VG      +C      GS  +  LC
Sbjct: 1859 GTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHC--LNTAGS--FHCLC 1914

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
              G  ++   +  + V    D +EC +  G C  GTC N  GSF C C  G+ +      
Sbjct: 1915 QDG--FELTADGKNCV----DTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQ-SDHC 1967

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     P++C  G C N PGS+ CLCP G+V   NG
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 67/219 (30%), Positives = 90/219 (41%), Gaps = 21/219 (9%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
            DVDEC+     C +G+CIN+ GS+ C C   Y   +  T C D  +     K      T 
Sbjct: 2363 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPK----PCTF 2418

Query: 67   TCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGGPGYQPVLE 121
             C+++      G+   C C  G      G  C    E  S  +  + LC    G      
Sbjct: 2419 LCKNTK-----GSFL-CSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRC 2472

Query: 122  PPSYVV---TLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
            PP +        D DEC+A  G C AHG C NT GSF C C  G++L             
Sbjct: 2473 PPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532

Query: 178  XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
              P  C  G C+N  G Y C CP+G+      +Q + +N
Sbjct: 2533 DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDEN 2570



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 48/125 (38%), Positives = 60/125 (48%), Gaps = 16/125 (12%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DVDEC++ P  CQ G C+N  GS+ CRCP  + L     AC D R   C+    L  G
Sbjct: 245 CQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSV--LFGG 302

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQLC-------PGGPG 115
               R + +L+   T   CCC  G  W  G   + CP  GS  ++QLC       PG PG
Sbjct: 303 ----RCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPG 358

Query: 116 YQPVL 120
             P L
Sbjct: 359 LFPGL 363



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 63/220 (28%), Positives = 87/220 (39%), Gaps = 27/220 (12%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
            G  C D+DEC S Q +CQ+  C+NT G++TCRCPP +       AC+D+ +         
Sbjct: 2441 GRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGF--TQHHQACFDNDECSAQPGPCG 2497

Query: 56   -YGKVDLRSGTETCRDSDELSEDGTMAAC---CCSVGAAWGNY-CDPCPEPGSEAYRQLC 110
             +G      G+  C    E  +  T+ +    C  V    G + C    +     YR  C
Sbjct: 2498 AHGHCHNTPGSFRC----ECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSC 2553

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
            P G          S      D +ECA     C   +C NT G F C C +G+        
Sbjct: 2554 PQG------FTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607

Query: 171  XXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     R   C    C N PG ++C CP+GY     G
Sbjct: 2608 CQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQG 2646



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 63/210 (30%), Positives = 85/210 (40%), Gaps = 25/210 (11%)

Query: 6    CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCYGKV 59
            C D+DEC   P+ C +  C NT+GS+ C CP  Y L  DG  C D     SR+  C    
Sbjct: 2403 CLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLC 2461

Query: 60   DLRSGTETCRDSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
                G  TCR     ++     AC     C +     G +      PGS  +R  C    
Sbjct: 2462 VNTVGAFTCRCPPGFTQH--HQACFDNDECSAQPGPCGAHGHCHNTPGS--FR--CECHQ 2515

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXX 173
            G+  V    S      D++EC      C HG C N  G + C+C  G++  +        
Sbjct: 2516 GFTLV----SSGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDE 2569

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  CG   CRN  G + C+CP G+
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGF 2599



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 58/167 (34%), Positives = 74/167 (44%), Gaps = 23/167 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-----ARCY-GKV 59
           C DVDEC S   C +G C+N  G+Y CRC P ++      AC D  +       C+ G+ 
Sbjct: 447 CIDVDECTS-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505

Query: 60  DLRSGTE--TCRDSDELSEDGTMAAC---CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
               G+    C    ELS DG        C +        C    E GS  +  LC   P
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVC--LNEDGS--FSCLCK--P 559

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
           G+  +L P  +     DIDEC    G+C +G CTNT GSF C C  G
Sbjct: 560 GF--LLAPGGHY--CMDIDECQT-PGICVNGHCTNTEGSFRCQCLGG 601



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 54/175 (30%), Positives = 65/175 (37%), Gaps = 19/175 (10%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARCYG 57
            G NC D DEC     C  G C N  G + C C   +E        D   C       C  
Sbjct: 2121 GINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDEC-SLNPLLCAF 2179

Query: 58   KVDLRSGTE--TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CP 111
            +     G+   TC     L EDG M   C  V        D C   G E    +    C 
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAM---CRDVDECADGQQD-CHARGMECKNLIGTFACV 2235

Query: 112  GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              PG +P+   P       D +EC A   LC +G C NT GSF C C  G+  +P
Sbjct: 2236 CPPGMRPL---PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSP 2287



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 19/210 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC D +EC +   C  G C+N  GS++C C P + L   G  C D  + +  G     
Sbjct: 526 GKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPG----- 580

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
                C +    + +G+   C C  G A G     C +      R  C G         P
Sbjct: 581 ----ICVNGHCTNTEGSFR-CQCLGGLAVGTDGRVCVDTH---VRSTCYGAIEKGSCARP 632

Query: 123 PSYVVTLADIDECAAHEGL---CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
               VT ++        G    C      N+   F   C +G  L               
Sbjct: 633 FPGTVTKSECCCANPDHGFGEPCQLCPAKNS-AEFQALCSSG--LGITTDGRDINECALD 689

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P+VC  GVC NL GSY C+C  GY A  +G
Sbjct: 690 PEVCANGVCENLRGSYRCVCNLGYEAGASG 719



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 59/187 (31%), Positives = 73/187 (39%), Gaps = 28/187 (14%)

Query: 21  GQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSGTETCRDSDELSEDGT 79
           G+CI   G   C C   +     G  C  D R   C+G+V    G E C+         T
Sbjct: 159 GRCI---GPNRCACVYGFM----GPQCERDYRTGPCFGQV----GPEGCQHQ-LTGLVCT 206

Query: 80  MAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHE 139
            A CC +VG AWG  C+ CP        Q  P   G+ P +    +     D+DEC A  
Sbjct: 207 KALCCATVGRAWGLPCELCPA-------QPHPCRRGFIPNI----HTGACQDVDECQAVP 255

Query: 140 GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR-NLPGSYV-- 196
           GLC  G+C N  GSF C C  G  L+                V   G C  +L G Y   
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRR 315

Query: 197 -CLCPEG 202
            C C  G
Sbjct: 316 QCCCDRG 322



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 26/177 (14%)

Query: 3    GFNCTDVDECKSPQ-SCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            GF C D+DEC S +  C   G C+N  GSY C C   +    DG  C D  +  C   VD
Sbjct: 1316 GFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCED--RDECAENVD 1371

Query: 61   LRSGTETC------RDSDELSEDGT--MAACCCSVGAAWGNYC--DPCPE-PGSEAYRQL 109
            L    +        R   E+  D T    AC      A GN C    C   PG   +R +
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPG--MFRCI 1429

Query: 110  CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
            C G  GY+  L+      T  DI+ECA     C +G C NT GS++C+C   + L P
Sbjct: 1430 CNG--GYE--LDRGGGNCT--DINECADPVN-CINGVCINTPGSYLCSCPQDFELNP 1479



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 61/210 (29%), Positives = 77/210 (36%), Gaps = 19/210 (9%)

Query: 9   VDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCY-GKVDLRS 63
           +D C+     C  G+C+ T  SY C C   Y     G  C D      + C+ G      
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHGDCVNIP 467

Query: 64  GTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           GT  CR         T  AC     C V    G  C       +E   Q C    G++  
Sbjct: 468 GTYHCRCYPGFQATPTRQACVDVDECIVS---GGLCHLGRCVNTEGSFQ-CVCNAGFE-- 521

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
           L P        D +ECA    +C +G C N  GSF C C  G+ LAP             
Sbjct: 522 LSPDGK--NCVDHNECATST-MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQT 578

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P +C  G C N  GS+ C C  G     +G
Sbjct: 579 PGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D+DECA +  LC +G C N+ GS+ C+C  G+                    C  GVCRN
Sbjct: 724 DVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVSGVCRN 782

Query: 191 LPGSYVCLCPEGYVAMPNGSQYLLQNLSTNMRLKIQ 226
           L GSY C C  G    P+G+ + L +      LKIQ
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT-FCLDSTKGTCWLKIQ 817



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX--XXXRP 180
            P  ++T  DIDEC+ +  LCA   C NT GS++CTC AG++L                + 
Sbjct: 2158 PGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQ 2216

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQ 211
            D    G+ C+NL G++ C+CP G   +P   +
Sbjct: 2217 DCHARGMECKNLIGTFACVCPPGMRPLPGSGE 2248



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 131  DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXXXXXXRPDVCGPGVC 188
            DIDEC     LC  GTC NT GSF C C  G+                   P +C  G C
Sbjct: 1028 DIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTC 1087

Query: 189  RNLPGSYVCLCPEGYVAMPNGS 210
             N  GSY C CP G+     G+
Sbjct: 1088 TNTDGSYKCQCPPGHELTAKGT 1109



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 55/211 (26%), Positives = 77/211 (36%), Gaps = 27/211 (12%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +CTDVDEC  +   C  G C N+ GSY+C CPP +    D                  
Sbjct: 719 GKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQD------------------ 760

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE-PGSEAYRQLCPGGPGYQPVL 120
              TE C+D DE      ++  C ++  ++   C P      S  +      G  +  + 
Sbjct: 761 ---TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQ 817

Query: 121 EPPSYV-VTLADI-DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           E    V +  A +  EC A  G      C          C  G++               
Sbjct: 818 ESRCEVNLQGASLRSECCATLGAAWGSPCERC--EIDPACARGFARMTGVTCDDVNECES 875

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            P VC  G C N  GS+ C CPEG +   +G
Sbjct: 876 FPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 127  VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
            +   D DEC+     C  GTCTN  G F C C  G+                 P +C   
Sbjct: 2122 INCVDTDECSVGHP-CGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR 2180

Query: 187  VCRNLPGSYVCLCPEGYVAMPNGS 210
             C N  GSY+C CP GY    +G+
Sbjct: 2181 -CHNTEGSYLCTCPAGYTLREDGA 2203



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCR 189
           D+DEC +    C HG C N  G++ C C  G+   P                +C  G C 
Sbjct: 449 DVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCV 506

Query: 190 NLPGSYVCLCPEGYVAMPNGSQYLLQN 216
           N  GS+ C+C  G+   P+G   +  N
Sbjct: 507 NTEGSFQCVCNAGFELSPDGKNCVDHN 533



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 11/24 (45%), Positives = 15/24 (62%)

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P +C  G C N+ GS+ C CP G+
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGH 278


>AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.
          Length = 2809

 Score =  193 bits (471), Expect = 4e-49
 Identities = 90/209 (43%), Positives = 112/209 (53%), Gaps = 6/209 (2%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G NCTD++EC  P +C  G CINT GSY C CP ++EL   G  C D+R   C+ +   R
Sbjct: 1440 GGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDR 1499

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
             G      S E+    T A+CCCS+G AWGN C+ CP   +  YR LCPGG G+Q    P
Sbjct: 1500 -GDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQ----P 1554

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPD 181
                V L DIDEC    GLC  G C NTFGSF C C  G+ L+                 
Sbjct: 1555 NRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSS 1614

Query: 182  VCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
            +CGPG C N  G+Y C+CP  Y+ +  G+
Sbjct: 1615 ICGPGTCYNTLGNYTCVCPAEYLQVNGGN 1643



 Score =  162 bits (393), Expect = 1e-39
 Identities = 83/205 (40%), Positives = 104/205 (50%), Gaps = 9/205 (4%)

Query: 1    MPGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            M G  C DV+EC+S P  C  G+C+NT GS+ C CP    L + G  C D R   C+   
Sbjct: 862  MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCF--- 918

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
             LR   + C  +  L     M  CCCS+GA WG  C+ CP+P S  +  LCP G G+   
Sbjct: 919  -LRWDEDECGVT--LPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS- 974

Query: 120  LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXX 178
             +  S      D++EC    GLC HGTC NT GSF C C  G++L A             
Sbjct: 975  RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGY 203
             PD+CG G C N PGS+ C C  GY
Sbjct: 1035 SPDLCGQGTCVNTPGSFECECFPGY 1059



 Score =  153 bits (370), Expect = 7e-37
 Identities = 80/209 (38%), Positives = 106/209 (50%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  CTD +EC + P  C  G+C+NT GS+ C C   ++     T C+D R+  C+ +V L
Sbjct: 2247 GEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV-L 2305

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++    CR     SE  T A CCC  G  WG  C+ CP PG+ AYR+LCP G G      
Sbjct: 2306 QT---MCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSG------ 2356

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               Y     D+DEC     LCAHG C N+ GSF C C AG++  A              P
Sbjct: 2357 ---YTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP 2413

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GS++C CP GY+   +G
Sbjct: 2414 KPC-TFLCKNTKGSFLCSCPRGYLLEEDG 2441



 Score =  147 bits (357), Expect = 2e-35
 Identities = 71/202 (35%), Positives = 106/202 (52%), Gaps = 14/202 (6%)

Query: 5    NCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D+DEC + P  C +G C N+ GS+ C CPP + L  +G  C+D+R++ C+ +     
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRF---- 2021

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
              E  + S   + + T   CCCS   G  WG+ C+ CP+ GS A+++LCP G G  P  +
Sbjct: 2022 --EAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPD 2079

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
                  +  D++ECA + G+C +G C NT GSF C C  G+SL                 
Sbjct: 2080 D-----SREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGH 2134

Query: 182  VCGPGVCRNLPGSYVCLCPEGY 203
             CG G C N+ G + C C +G+
Sbjct: 2135 PCGQGTCTNVIGGFECACADGF 2156



 Score =  138 bits (333), Expect = 2e-32
 Identities = 79/211 (37%), Positives = 102/211 (48%), Gaps = 17/211 (8%)

Query: 6    CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC +  S C  G C NT G+YTC CP  Y  V+ G  C D RK+ C+     R  
Sbjct: 1603 CEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCF-----RHY 1657

Query: 65   TETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPG-GPGYQPVLE 121
              TC+  +EL+ + T   CCCS  +G AW   C+ CP P S  Y+ LC    PG+   + 
Sbjct: 1658 NGTCQ--NELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIH 1715

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                +    DIDEC     +CA+G C N  GSF C C AG++  +             R 
Sbjct: 1716 TGKPL----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRE 1771

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGS 210
              C     C N+PGSY C C  GY   P G+
Sbjct: 1772 SPCQQNADCINIPGSYRCKCTRGYKLSPGGA 1802



 Score =  120 bits (290), Expect = 3e-27
 Identities = 65/203 (32%), Positives = 91/203 (44%), Gaps = 16/203 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  C D+DEC++P  C  G C NT+GS+ C+C     + +DG  C D+  ++ CYG ++ 
Sbjct: 567 GHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEK 626

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            S       +   SE      CC +    +G  C  CP   S  ++ LC  G G      
Sbjct: 627 GSCARPFPGTVTKSE-----CCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLG------ 675

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                    DI+ECA    +CA+G C N  GS+ C C  G+   A               
Sbjct: 676 ---ITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732

Query: 181 DVCGPGVCRNLPGSYVCLCPEGY 203
            +C  G C+N PGSY C CP G+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGF 755



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 72/222 (32%), Positives = 95/222 (42%), Gaps = 32/222 (14%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  G C+NT GS+ C C P YE    G     +    C    +   
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYE---SGFMLMKN----CMDVDECAR 1077

Query: 64   GTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPE--------PGSEAYRQL--- 109
                CR     + DG+   C C  G    A G  C+   E        P  +    +   
Sbjct: 1078 DPLLCRGGTCTNTDGSYK-CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAF 1136

Query: 110  -CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPX 167
             C    G+Q   +    V    DI+EC    G C  H  C NT GS+ C+CG G+SL P 
Sbjct: 1137 QCSCHAGFQSTPDRQGCV----DINECRVQNGGCDVH--CINTEGSYRCSCGQGYSLMPD 1190

Query: 168  XXXXXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                         P VC  G C N+PG + CLC +G++A P+
Sbjct: 1191 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232



 Score = 99.1 bits (236), Expect = 1e-20
 Identities = 70/214 (32%), Positives = 92/214 (42%), Gaps = 20/214 (9%)

Query: 6    CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            C+DVDEC+    +C  +  C+N  GS++CRC P +  V DG  C+D  +  C  +    S
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECHDLDE--CVSQEHRCS 1333

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQPV 119
                C     L+  G+    C    A  G +C   D C E         C   PG Y+  
Sbjct: 1334 PRGDC-----LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCE 1388

Query: 120  LE----PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E    P        D+DECA    LCA G+C N  G F C C  G+ L           
Sbjct: 1389 CEMGFDPTEDHRACQDVDECA-QGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDIN 1447

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                P  C  GVC N PGSY+C CP+ +   P+G
Sbjct: 1448 ECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 59/160 (36%), Positives = 74/160 (46%), Gaps = 22/160 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC S   C  G C N  GSYTC+C P   L   GT C DS K  C+ K+      
Sbjct: 764 CKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKI------ 816

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-EPGSEAYRQLCPGGPGYQPVLEPPS 124
           +  R    L      + CC ++GAAWG+ C+ C  +P        C  G           
Sbjct: 817 QESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPA-------CARGFARMT------ 863

Query: 125 YVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
             VT  D++EC +  G+C +G C NT GSF C C  G  L
Sbjct: 864 -GVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLML 902



 Score = 89.8 bits (213), Expect = 7e-18
 Identities = 63/215 (29%), Positives = 88/215 (40%), Gaps = 22/215 (10%)

Query: 3    GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVD 60
            G  C D+DEC  S   C +GQC+N  G++ C C   ++   D   C D  + R   G  D
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1167

Query: 61   LRS-GTE-----TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
            +    TE     +C     L  DG     C  V     + C+  P    + +    PGG 
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGR---ACADV-----DECEENPRVCDQGHCTNMPGGH 1219

Query: 115  G---YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX-- 169
                Y   +  P  + T  D+DEC  +  +C HG C NT GSFVC C  G+ +       
Sbjct: 1220 RCLCYDGFMATPD-MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGC 1278

Query: 170  XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +      C N+PGS+ C C  G+V
Sbjct: 1279 SDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV 1313



 Score = 86.6 bits (205), Expect = 6e-17
 Identities = 65/219 (29%), Positives = 93/219 (42%), Gaps = 22/219 (10%)

Query: 2    PGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCY 56
            PG  C   +EC+  P  C +G C++T+GSY C C   ++  +D T C D     R+    
Sbjct: 1799 PGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGN 1858

Query: 57   GKVDLRSGTETCR--DSDELSEDGTMA---ACCCSVGAAWG-NYCDPCPEPGSEAYRQLC 110
            G      G+  C       ++ +G       C   VG      +C      GS  +  LC
Sbjct: 1859 GTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHC--LNTAGS--FHCLC 1914

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
              G  ++   +  + V    D +EC +  G C  GTC N  GSF C C  G+ +      
Sbjct: 1915 QDG--FELTADGKNCV----DTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQ-SDHC 1967

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     P++C  G C N PGS+ CLCP G+V   NG
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 67/219 (30%), Positives = 90/219 (41%), Gaps = 21/219 (9%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
            DVDEC+     C +G+CIN+ GS+ C C   Y   +  T C D  +     K      T 
Sbjct: 2363 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPK----PCTF 2418

Query: 67   TCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGGPGYQPVLE 121
             C+++      G+   C C  G      G  C    E  S  +  + LC    G      
Sbjct: 2419 LCKNTK-----GSFL-CSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRC 2472

Query: 122  PPSYVV---TLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
            PP +        D DEC+A  G C AHG C NT GSF C C  G++L             
Sbjct: 2473 PPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532

Query: 178  XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
              P  C  G C+N  G Y C CP+G+      +Q + +N
Sbjct: 2533 DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDEN 2570



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 48/125 (38%), Positives = 60/125 (48%), Gaps = 16/125 (12%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DVDEC++ P  CQ G C+N  GS+ CRCP  + L     AC D R   C+    L  G
Sbjct: 245 CQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSV--LFGG 302

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQLC-------PGGPG 115
               R + +L+   T   CCC  G  W  G   + CP  GS  ++QLC       PG PG
Sbjct: 303 ----RCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPG 358

Query: 116 YQPVL 120
             P L
Sbjct: 359 LFPGL 363



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 63/220 (28%), Positives = 87/220 (39%), Gaps = 27/220 (12%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
            G  C D+DEC S Q +CQ+  C+NT G++TCRCPP +       AC+D+ +         
Sbjct: 2441 GRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGF--TQHHQACFDNDECSAQPGPCG 2497

Query: 56   -YGKVDLRSGTETCRDSDELSEDGTMAAC---CCSVGAAWGNY-CDPCPEPGSEAYRQLC 110
             +G      G+  C    E  +  T+ +    C  V    G + C    +     YR  C
Sbjct: 2498 AHGHCHNTPGSFRC----ECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSC 2553

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
            P G          S      D +ECA     C   +C NT G F C C +G+        
Sbjct: 2554 PQG------FTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2607

Query: 171  XXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     R   C    C N PG ++C CP+GY     G
Sbjct: 2608 CQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQG 2646



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 63/210 (30%), Positives = 85/210 (40%), Gaps = 25/210 (11%)

Query: 6    CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCYGKV 59
            C D+DEC   P+ C +  C NT+GS+ C CP  Y L  DG  C D     SR+  C    
Sbjct: 2403 CLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLC 2461

Query: 60   DLRSGTETCRDSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
                G  TCR     ++     AC     C +     G +      PGS  +R  C    
Sbjct: 2462 VNTVGAFTCRCPPGFTQH--HQACFDNDECSAQPGPCGAHGHCHNTPGS--FR--CECHQ 2515

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXX 173
            G+  V    S      D++EC      C HG C N  G + C+C  G++  +        
Sbjct: 2516 GFTLV----SSGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDE 2569

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  CG   CRN  G + C+CP G+
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGF 2599



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 57/167 (34%), Positives = 74/167 (44%), Gaps = 23/167 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-----ARCY-GKV 59
           C DVDEC S   C +G C+N  G+Y C+C P ++      AC D  +       C+ G+ 
Sbjct: 447 CIDVDECTS-SPCHHGDCVNIPGTYHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505

Query: 60  DLRSGTE--TCRDSDELSEDGTMAAC---CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
               G+    C    ELS DG        C +        C    E GS  +  LC   P
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVC--LNEDGS--FSCLCK--P 559

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
           G+  +L P  +     DIDEC    G+C +G CTNT GSF C C  G
Sbjct: 560 GF--LLAPGGHY--CMDIDECQT-PGICVNGHCTNTEGSFRCQCLGG 601



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 54/175 (30%), Positives = 65/175 (37%), Gaps = 19/175 (10%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARCYG 57
            G NC D DEC     C  G C N  G + C C   +E        D   C       C  
Sbjct: 2121 GINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDEC-SLNPLLCAF 2179

Query: 58   KVDLRSGTE--TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CP 111
            +     G+   TC     L EDG M   C  V        D C   G E    +    C 
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAM---CRDVDECADGQQD-CHARGMECKNLIGTFACV 2235

Query: 112  GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              PG +P+   P       D +EC A   LC +G C NT GSF C C  G+  +P
Sbjct: 2236 CPPGMRPL---PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSP 2287



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 19/210 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC D +EC +   C  G C+N  GS++C C P + L   G  C D  + +  G     
Sbjct: 526 GKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPG----- 580

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
                C +    + +G+   C C  G A G     C +      R  C G         P
Sbjct: 581 ----ICVNGHCTNTEGSFR-CQCLGGLAVGTDGRVCVDTH---VRSTCYGAIEKGSCARP 632

Query: 123 PSYVVTLADIDECAAHEGL---CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
               VT ++        G    C      N+   F   C +G  L               
Sbjct: 633 FPGTVTKSECCCANPDHGFGEPCQLCPAKNS-AEFQALCSSG--LGITTDGRDINECALD 689

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P+VC  GVC NL GSY C+C  GY A  +G
Sbjct: 690 PEVCANGVCENLRGSYRCVCNLGYEAGASG 719



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 59/187 (31%), Positives = 73/187 (39%), Gaps = 28/187 (14%)

Query: 21  GQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSGTETCRDSDELSEDGT 79
           G+CI   G   C C   +     G  C  D R   C+G+V    G E C+         T
Sbjct: 159 GRCI---GPNRCACVYGFM----GPQCERDYRTGPCFGQV----GPEGCQHQ-LTGLVCT 206

Query: 80  MAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHE 139
            A CC +VG AWG  C+ CP        Q  P   G+ P +    +     D+DEC A  
Sbjct: 207 KALCCATVGRAWGLPCELCPA-------QPHPCRRGFIPNI----HTGACQDVDECQAVP 255

Query: 140 GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR-NLPGSYV-- 196
           GLC  G+C N  GSF C C  G  L+                V   G C  +L G Y   
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRR 315

Query: 197 -CLCPEG 202
            C C  G
Sbjct: 316 QCCCDRG 322



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 26/177 (14%)

Query: 3    GFNCTDVDECKSPQ-SCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            GF C D+DEC S +  C   G C+N  GSY C C   +    DG  C D  +  C   VD
Sbjct: 1316 GFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCED--RDECAENVD 1371

Query: 61   LRSGTETC------RDSDELSEDGT--MAACCCSVGAAWGNYC--DPCPE-PGSEAYRQL 109
            L    +        R   E+  D T    AC      A GN C    C   PG   +R +
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPG--MFRCI 1429

Query: 110  CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
            C G  GY+  L+      T  DI+ECA     C +G C NT GS++C+C   + L P
Sbjct: 1430 CNG--GYE--LDRGGGNCT--DINECADPVN-CINGVCINTPGSYLCSCPQDFELNP 1479



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 60/210 (28%), Positives = 77/210 (36%), Gaps = 19/210 (9%)

Query: 9   VDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCY-GKVDLRS 63
           +D C+     C  G+C+ T  SY C C   Y     G  C D      + C+ G      
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHGDCVNIP 467

Query: 64  GTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           GT  C+         T  AC     C V    G  C       +E   Q C    G++  
Sbjct: 468 GTYHCQCYPGFQATPTRQACVDVDECIVS---GGLCHLGRCVNTEGSFQ-CVCNAGFE-- 521

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
           L P        D +ECA    +C +G C N  GSF C C  G+ LAP             
Sbjct: 522 LSPDGK--NCVDHNECATST-MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQT 578

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P +C  G C N  GS+ C C  G     +G
Sbjct: 579 PGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D+DECA +  LC +G C N+ GS+ C+C  G+                    C  GVCRN
Sbjct: 724 DVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVSGVCRN 782

Query: 191 LPGSYVCLCPEGYVAMPNGSQYLLQNLSTNMRLKIQ 226
           L GSY C C  G    P+G+ + L +      LKIQ
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT-FCLDSTKGTCWLKIQ 817



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX--XXXRP 180
            P  ++T  DIDEC+ +  LCA   C NT GS++CTC AG++L                + 
Sbjct: 2158 PGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQ 2216

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQ 211
            D    G+ C+NL G++ C+CP G   +P   +
Sbjct: 2217 DCHARGMECKNLIGTFACVCPPGMRPLPGSGE 2248



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 131  DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXXXXXXRPDVCGPGVC 188
            DIDEC     LC  GTC NT GSF C C  G+                   P +C  G C
Sbjct: 1028 DIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTC 1087

Query: 189  RNLPGSYVCLCPEGYVAMPNGS 210
             N  GSY C CP G+     G+
Sbjct: 1088 TNTDGSYKCQCPPGHELTAKGT 1109



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 55/211 (26%), Positives = 77/211 (36%), Gaps = 27/211 (12%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +CTDVDEC  +   C  G C N+ GSY+C CPP +    D                  
Sbjct: 719 GKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQD------------------ 760

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE-PGSEAYRQLCPGGPGYQPVL 120
              TE C+D DE      ++  C ++  ++   C P      S  +      G  +  + 
Sbjct: 761 ---TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQ 817

Query: 121 EPPSYV-VTLADI-DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           E    V +  A +  EC A  G      C          C  G++               
Sbjct: 818 ESRCEVNLQGASLRSECCATLGAAWGSPCERC--EIDPACARGFARMTGVTCDDVNECES 875

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            P VC  G C N  GS+ C CPEG +   +G
Sbjct: 876 FPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 127  VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
            +   D DEC+     C  GTCTN  G F C C  G+                 P +C   
Sbjct: 2122 INCVDTDECSVGHP-CGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR 2180

Query: 187  VCRNLPGSYVCLCPEGYVAMPNGS 210
             C N  GSY+C CP GY    +G+
Sbjct: 2181 -CHNTEGSYLCTCPAGYTLREDGA 2203



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCR 189
           D+DEC +    C HG C N  G++ C C  G+   P                +C  G C 
Sbjct: 449 DVDECTSSP--CHHGDCVNIPGTYHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGRCV 506

Query: 190 NLPGSYVCLCPEGYVAMPNGSQYLLQN 216
           N  GS+ C+C  G+   P+G   +  N
Sbjct: 507 NTEGSFQCVCNAGFELSPDGKNCVDHN 533



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 11/24 (45%), Positives = 15/24 (62%)

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P +C  G C N+ GS+ C CP G+
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGH 278


>AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.
          Length = 2816

 Score =  193 bits (470), Expect = 5e-49
 Identities = 90/209 (43%), Positives = 112/209 (53%), Gaps = 6/209 (2%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G NCTD++EC  P +C  G CINT GSY C CP ++EL   G  C D+R   C+ +   R
Sbjct: 1447 GGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDR 1506

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
             G      S E+    T A+CCCS+G AWGN C+ CP   +  YR LCPGG G+Q    P
Sbjct: 1507 -GDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQ----P 1561

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPD 181
                V L DIDEC    GLC  G C NTFGSF C C  G+ L+                 
Sbjct: 1562 NRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSG 1621

Query: 182  VCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
            +CGPG C N  G+Y C+CP  Y+ +  G+
Sbjct: 1622 ICGPGTCYNTLGNYTCVCPAEYLQVNGGN 1650



 Score =  162 bits (393), Expect = 1e-39
 Identities = 83/205 (40%), Positives = 104/205 (50%), Gaps = 9/205 (4%)

Query: 1    MPGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            M G  C DV+EC+S P  C  G+C+NT GS+ C CP    L + G  C D R   C+   
Sbjct: 869  MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCF--- 925

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
             LR   + C  +  L     M  CCCS+GA WG  C+ CP+P S  +  LCP G G+   
Sbjct: 926  -LRWDEDECGVT--LPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS- 981

Query: 120  LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXX 178
             +  S      D++EC    GLC HGTC NT GSF C C  G++L A             
Sbjct: 982  RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1041

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGY 203
             PD+CG G C N PGS+ C C  GY
Sbjct: 1042 SPDLCGQGTCVNTPGSFECECFPGY 1066



 Score =  153 bits (370), Expect = 7e-37
 Identities = 80/209 (38%), Positives = 106/209 (50%), Gaps = 16/209 (7%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  CTD +EC + P  C  G+C+NT GS+ C C   ++     T C+D R+  C+ +V L
Sbjct: 2254 GEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV-L 2312

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            ++    CR     SE  T A CCC  G  WG  C+ CP PG+ AYR+LCP G G      
Sbjct: 2313 QT---MCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSG------ 2363

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
               Y     D+DEC     LCAHG C N+ GSF C C AG++  A              P
Sbjct: 2364 ---YTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP 2420

Query: 181  DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              C   +C+N  GS++C CP GY+   +G
Sbjct: 2421 KPC-TFLCKNTKGSFLCSCPRGYLLEEDG 2448



 Score =  147 bits (357), Expect = 2e-35
 Identities = 71/202 (35%), Positives = 106/202 (52%), Gaps = 14/202 (6%)

Query: 5    NCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D+DEC + P  C +G C N+ GS+ C CPP + L  +G  C+D+R++ C+ +     
Sbjct: 1973 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRF---- 2028

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
              E  + S   + + T   CCCS   G  WG+ C+ CP+ GS A+++LCP G G  P  +
Sbjct: 2029 --EAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPD 2086

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
                  +  D++ECA + G+C +G C NT GSF C C  G+SL                 
Sbjct: 2087 D-----SREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGH 2141

Query: 182  VCGPGVCRNLPGSYVCLCPEGY 203
             CG G C N+ G + C C +G+
Sbjct: 2142 PCGQGTCTNVIGGFECACADGF 2163



 Score =  136 bits (329), Expect = 6e-32
 Identities = 78/211 (36%), Positives = 101/211 (47%), Gaps = 17/211 (8%)

Query: 6    CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D+DEC +    C  G C NT G+YTC CP  Y  V+ G  C D RK+ C+     R  
Sbjct: 1610 CEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCF-----RHY 1664

Query: 65   TETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPG-GPGYQPVLE 121
              TC+  +EL+ + T   CCCS  +G AW   C+ CP P S  Y+ LC    PG+   + 
Sbjct: 1665 NGTCQ--NELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIH 1722

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                +    DIDEC     +CA+G C N  GSF C C AG++  +             R 
Sbjct: 1723 TGKPL----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRE 1778

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGS 210
              C     C N+PGSY C C  GY   P G+
Sbjct: 1779 SPCQQNADCINIPGSYRCKCTRGYKLSPGGA 1809



 Score =  120 bits (290), Expect = 3e-27
 Identities = 65/203 (32%), Positives = 91/203 (44%), Gaps = 16/203 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  C D+DEC++P  C  G C NT+GS+ C+C     + +DG  C D+  ++ CYG ++ 
Sbjct: 574 GHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEK 633

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
            S       +   SE      CC +    +G  C  CP   S  ++ LC  G G      
Sbjct: 634 GSCARPFPGTVTKSE-----CCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLG------ 682

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
                    DI+ECA    +CA+G C N  GS+ C C  G+   A               
Sbjct: 683 ---ITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 739

Query: 181 DVCGPGVCRNLPGSYVCLCPEGY 203
            +C  G C+N PGSY C CP G+
Sbjct: 740 LLCDNGWCQNSPGSYSCSCPPGF 762



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 72/222 (32%), Positives = 95/222 (42%), Gaps = 32/222 (14%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  G C+NT GS+ C C P YE    G     +    C    +   
Sbjct: 1032 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYE---SGFMLMKN----CMDVDECAR 1084

Query: 64   GTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPE--------PGSEAYRQL--- 109
                CR     + DG+   C C  G    A G  C+   E        P  +    +   
Sbjct: 1085 DPLLCRGGTCTNTDGSYK-CQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAF 1143

Query: 110  -CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPX 167
             C    G+Q   +    V    DI+EC    G C  H  C NT GS+ C+CG G+SL P 
Sbjct: 1144 QCSCHAGFQSTPDRQGCV----DINECRVQNGGCDVH--CINTEGSYRCSCGQGYSLMPD 1197

Query: 168  XXXXXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                         P VC  G C N+PG + CLC +G++A P+
Sbjct: 1198 GRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1239



 Score = 99.1 bits (236), Expect = 1e-20
 Identities = 70/214 (32%), Positives = 92/214 (42%), Gaps = 20/214 (9%)

Query: 6    CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            C+DVDEC+    +C  +  C+N  GS++CRC P +  V DG  C+D  +  C  +    S
Sbjct: 1285 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECHDLDE--CISQEHRCS 1340

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQPV 119
                C     L+  G+    C    A  G +C   D C E         C   PG Y+  
Sbjct: 1341 PRGDC-----LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCE 1395

Query: 120  LE----PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E    P        D+DECA    LCA G+C N  G F C C  G+ L           
Sbjct: 1396 CEMGFDPTEDHRACQDVDECA-QGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDIN 1454

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                P  C  GVC N PGSY+C CP+ +   P+G
Sbjct: 1455 ECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1488



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 59/160 (36%), Positives = 74/160 (46%), Gaps = 22/160 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC S   C  G C N  GSYTC+C P   L   GT C DS K  C+ K+      
Sbjct: 771 CKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKI------ 823

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-EPGSEAYRQLCPGGPGYQPVLEPPS 124
           +  R    L      + CC ++GAAWG+ C+ C  +P        C  G           
Sbjct: 824 QESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPA-------CARGFARMT------ 870

Query: 125 YVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
             VT  D++EC +  G+C +G C NT GSF C C  G  L
Sbjct: 871 -GVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLML 909



 Score = 89.8 bits (213), Expect = 7e-18
 Identities = 63/215 (29%), Positives = 88/215 (40%), Gaps = 22/215 (10%)

Query: 3    GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVD 60
            G  C D+DEC  S   C +GQC+N  G++ C C   ++   D   C D  + R   G  D
Sbjct: 1115 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD 1174

Query: 61   LRS-GTE-----TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
            +    TE     +C     L  DG     C  V     + C+  P    + +    PGG 
Sbjct: 1175 VHCINTEGSYRCSCGQGYSLMPDGR---ACADV-----DECEENPRVCDQGHCTNMPGGH 1226

Query: 115  G---YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX-- 169
                Y   +  P  + T  D+DEC  +  +C HG C NT GSFVC C  G+ +       
Sbjct: 1227 RCLCYDGFMATPD-MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGC 1285

Query: 170  XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +      C N+PGS+ C C  G+V
Sbjct: 1286 SDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV 1320



 Score = 87.0 bits (206), Expect = 5e-17
 Identities = 65/219 (29%), Positives = 93/219 (42%), Gaps = 22/219 (10%)

Query: 2    PGFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCY 56
            PG  C   +EC+  P  C +G C++T+GSY C C   ++  +D T C D     R+    
Sbjct: 1806 PGGACVGQNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGN 1865

Query: 57   GKVDLRSGTETCR--DSDELSEDGTMA---ACCCSVGAAWG-NYCDPCPEPGSEAYRQLC 110
            G      G+  C       ++ +G       C   VG      +C      GS  +  LC
Sbjct: 1866 GTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHC--LNTAGS--FHCLC 1921

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
              G  ++   +  + V    D +EC +  G C  GTC N  GSF C C  G+ +      
Sbjct: 1922 QDG--FELTADGKNCV----DTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQ-SDHC 1974

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     P++C  G C N PGS+ CLCP G+V   NG
Sbjct: 1975 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2013



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 67/219 (30%), Positives = 90/219 (41%), Gaps = 21/219 (9%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
            DVDEC+     C +G+CIN+ GS+ C C   Y   +  T C D  +     K      T 
Sbjct: 2370 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPK----PCTF 2425

Query: 67   TCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAY--RQLCPGGPGYQPVLE 121
             C+++      G+   C C  G      G  C    E  S  +  + LC    G      
Sbjct: 2426 LCKNTK-----GSFL-CSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRC 2479

Query: 122  PPSYVV---TLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
            PP +        D DEC+A  G C AHG C NT GSF C C  G++L             
Sbjct: 2480 PPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2539

Query: 178  XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
              P  C  G C+N  G Y C CP+G+      +Q + +N
Sbjct: 2540 DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDEN 2577



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 48/125 (38%), Positives = 60/125 (48%), Gaps = 16/125 (12%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DVDEC++ P  CQ G C+N  GS+ CRCP  + L     AC D R   C+    L  G
Sbjct: 252 CQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSV--LFGG 309

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQLC-------PGGPG 115
               R + +L+   T   CCC  G  W  G   + CP  GS  ++QLC       PG PG
Sbjct: 310 ----RCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPG 365

Query: 116 YQPVL 120
             P L
Sbjct: 366 LFPGL 370



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 63/220 (28%), Positives = 87/220 (39%), Gaps = 27/220 (12%)

Query: 3    GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
            G  C D+DEC S Q +CQ+  C+NT G++TCRCPP +       AC+D+ +         
Sbjct: 2448 GRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGF--TQHHQACFDNDECSAQPGPCG 2504

Query: 56   -YGKVDLRSGTETCRDSDELSEDGTMAAC---CCSVGAAWGNY-CDPCPEPGSEAYRQLC 110
             +G      G+  C    E  +  T+ +    C  V    G + C    +     YR  C
Sbjct: 2505 AHGHCHNTPGSFRC----ECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSC 2560

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
            P G          S      D +ECA     C   +C NT G F C C +G+        
Sbjct: 2561 PQG------FTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGG 2614

Query: 171  XXXXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                     R   C    C N PG ++C CP+GY     G
Sbjct: 2615 CQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQG 2653



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 63/210 (30%), Positives = 85/210 (40%), Gaps = 25/210 (11%)

Query: 6    CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCYGKV 59
            C D+DEC   P+ C +  C NT+GS+ C CP  Y L  DG  C D     SR+  C    
Sbjct: 2410 CLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLC 2468

Query: 60   DLRSGTETCRDSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
                G  TCR     ++     AC     C +     G +      PGS  +R  C    
Sbjct: 2469 VNTVGAFTCRCPPGFTQH--HQACFDNDECSAQPGPCGAHGHCHNTPGS--FR--CECHQ 2522

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXX 173
            G+  V    S      D++EC      C HG C N  G + C+C  G++  +        
Sbjct: 2523 GFTLV----SSGHGCEDVNECDGPH-RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDE 2576

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  CG   CRN  G + C+CP G+
Sbjct: 2577 NECALSPPTCGSASCRNTLGGFRCVCPSGF 2606



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 58/167 (34%), Positives = 74/167 (44%), Gaps = 23/167 (13%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-----ARCY-GKV 59
           C DVDEC S   C +G C+N  G+Y CRC P ++      AC D  +       C+ G+ 
Sbjct: 454 CIDVDECTS-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 512

Query: 60  DLRSGTE--TCRDSDELSEDGTMAAC---CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
               G+    C    ELS DG        C +        C    E GS  +  LC   P
Sbjct: 513 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVC--LNEDGS--FSCLCK--P 566

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
           G+  +L P  +     DIDEC    G+C +G CTNT GSF C C  G
Sbjct: 567 GF--LLAPGGHY--CMDIDECQT-PGICVNGHCTNTEGSFRCQCLGG 608



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 54/175 (30%), Positives = 65/175 (37%), Gaps = 19/175 (10%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARCYG 57
            G NC D DEC     C  G C N  G + C C   +E        D   C       C  
Sbjct: 2128 GINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDEC-SLNPLLCAF 2186

Query: 58   KVDLRSGTE--TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CP 111
            +     G+   TC     L EDG M   C  V        D C   G E    +    C 
Sbjct: 2187 RCHNTEGSYLCTCPAGYTLREDGAM---CRDVDECADGQQD-CHARGMECKNLIGTFACV 2242

Query: 112  GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              PG +P+   P       D +EC A   LC +G C NT GSF C C  G+  +P
Sbjct: 2243 CPPGMRPL---PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSP 2294



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 19/210 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC D +EC +   C  G C+N  GS++C C P + L   G  C D  + +  G     
Sbjct: 533 GKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPG----- 587

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
                C +    + +G+   C C  G A G     C +      R  C G         P
Sbjct: 588 ----ICVNGHCTNTEGSFR-CQCLGGLAVGTDGRVCVDTH---VRSTCYGAIEKGSCARP 639

Query: 123 PSYVVTLADIDECAAHEGL---CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
               VT ++        G    C      N+   F   C +G  L               
Sbjct: 640 FPGTVTKSECCCANPDHGFGEPCQLCPAKNS-AEFQALCSSG--LGITTDGRDINECALD 696

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P+VC  GVC NL GSY C+C  GY A  +G
Sbjct: 697 PEVCANGVCENLRGSYRCVCNLGYEAGASG 726



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 59/187 (31%), Positives = 73/187 (39%), Gaps = 28/187 (14%)

Query: 21  GQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSGTETCRDSDELSEDGT 79
           G+CI   G   C C   +     G  C  D R   C+G+V    G E C+         T
Sbjct: 166 GRCI---GPNRCACVYGFM----GPQCERDYRTGPCFGQV----GPEGCQHQ-LTGLVCT 213

Query: 80  MAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHE 139
            A CC +VG AWG  C+ CP        Q  P   G+ P +    +     D+DEC A  
Sbjct: 214 KALCCATVGRAWGLPCELCPA-------QPHPCRRGFIPNI----HTGACQDVDECQAVP 262

Query: 140 GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR-NLPGSYV-- 196
           GLC  G+C N  GSF C C  G  L+                V   G C  +L G Y   
Sbjct: 263 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRR 322

Query: 197 -CLCPEG 202
            C C  G
Sbjct: 323 QCCCDRG 329



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 61/210 (29%), Positives = 77/210 (36%), Gaps = 19/210 (9%)

Query: 9   VDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCY-GKVDLRS 63
           +D C+     C  G+C+ T  SY C C   Y     G  C D      + C+ G      
Sbjct: 416 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHGDCVNIP 474

Query: 64  GTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           GT  CR         T  AC     C V    G  C       +E   Q C    G++  
Sbjct: 475 GTYHCRCYPGFQATPTRQACVDVDECIVS---GGLCHLGRCVNTEGSFQ-CVCNAGFE-- 528

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
           L P        D +ECA    +C +G C N  GSF C C  G+ LAP             
Sbjct: 529 LSPDGK--NCVDHNECATST-MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQT 585

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           P +C  G C N  GS+ C C  G     +G
Sbjct: 586 PGICVNGHCTNTEGSFRCQCLGGLAVGTDG 615



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 26/177 (14%)

Query: 3    GFNCTDVDECKSPQ-SCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            GF C D+DEC S +  C   G C+N  GSY C C   +    DG  C D  +  C   VD
Sbjct: 1323 GFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCED--RDECAENVD 1378

Query: 61   LRSGTETC------RDSDELSEDGT--MAACCCSVGAAWGNYC--DPCPE-PGSEAYRQL 109
            L    +        R   E+  D T    AC      A GN C    C   PG   +R +
Sbjct: 1379 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPG--MFRCI 1436

Query: 110  CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
            C G  GY+  L+      T  DI+ECA     C +G C NT GS++C+C   + L P
Sbjct: 1437 CNG--GYE--LDRGGGNCT--DINECADPVN-CINGVCINTPGSYLCSCPQDFELNP 1486



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D+DECA +  LC +G C N+ GS+ C+C  G+                    C  GVCRN
Sbjct: 731 DVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVSGVCRN 789

Query: 191 LPGSYVCLCPEGYVAMPNGSQYLLQNLSTNMRLKIQ 226
           L GSY C C  G    P+G+ + L +      LKIQ
Sbjct: 790 LAGSYTCKCGPGSRLDPSGT-FCLDSTKGTCWLKIQ 824



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 123  PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX--XXXRP 180
            P  ++T  DIDEC+ +  LCA   C NT GS++CTC AG++L                + 
Sbjct: 2165 PGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQ 2223

Query: 181  DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQ 211
            D    G+ C+NL G++ C+CP G   +P   +
Sbjct: 2224 DCHARGMECKNLIGTFACVCPPGMRPLPGSGE 2255



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 131  DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXXXXXXRPDVCGPGVC 188
            DIDEC     LC  GTC NT GSF C C  G+                   P +C  G C
Sbjct: 1035 DIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTC 1094

Query: 189  RNLPGSYVCLCPEGYVAMPNGS 210
             N  GSY C CP G+     G+
Sbjct: 1095 TNTDGSYKCQCPPGHELTAKGT 1116



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 55/211 (26%), Positives = 77/211 (36%), Gaps = 27/211 (12%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +CTDVDEC  +   C  G C N+ GSY+C CPP +    D                  
Sbjct: 726 GKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQD------------------ 767

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE-PGSEAYRQLCPGGPGYQPVL 120
              TE C+D DE      ++  C ++  ++   C P      S  +      G  +  + 
Sbjct: 768 ---TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQ 824

Query: 121 EPPSYV-VTLADI-DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           E    V +  A +  EC A  G      C          C  G++               
Sbjct: 825 ESRCEVNLQGASLRSECCATLGAAWGSPCERC--EIDPACARGFARMTGVTCDDVNECES 882

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            P VC  G C N  GS+ C CPEG +   +G
Sbjct: 883 FPGVCPNGRCVNTAGSFRCECPEGLMLDASG 913



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 127  VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
            +   D DEC+     C  GTCTN  G F C C  G+                 P +C   
Sbjct: 2129 INCVDTDECSVGHP-CGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR 2187

Query: 187  VCRNLPGSYVCLCPEGYVAMPNGS 210
             C N  GSY+C CP GY    +G+
Sbjct: 2188 -CHNTEGSYLCTCPAGYTLREDGA 2210



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCR 189
           D+DEC +    C HG C N  G++ C C  G+   P                +C  G C 
Sbjct: 456 DVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCV 513

Query: 190 NLPGSYVCLCPEGYVAMPNGSQYLLQN 216
           N  GS+ C+C  G+   P+G   +  N
Sbjct: 514 NTEGSFQCVCNAGFELSPDGKNCVDHN 540



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 11/24 (45%), Positives = 15/24 (62%)

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P +C  G C N+ GS+ C CP G+
Sbjct: 262 PGLCQGGSCVNMVGSFHCRCPVGH 285


>X62009-1|CAB56757.1|  754|Homo sapiens fibrillin 5 protein.
          Length = 754

 Score =  168 bits (408), Expect = 2e-41
 Identities = 81/203 (39%), Positives = 108/203 (53%), Gaps = 8/203 (3%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C DV+EC+  P  C  G+C+N++GS+ C CP    L   G  C D R  +CY K D 
Sbjct: 198 GVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWD- 256

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
               + C     +     M ACCC+VGAAWG  C+ CP+PG++ Y  LCP G G+    +
Sbjct: 257 ---EDEC--IHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGD 311

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
             +      DI+EC A  G+C +G C NT GSF C C +G++L                P
Sbjct: 312 VLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISP 371

Query: 181 DVCGPGVCRNLPGSYVCLCPEGY 203
           D+CG G+C N PGS+ C C EGY
Sbjct: 372 DLCGSGICVNTPGSFECECFEGY 394



 Score = 97.1 bits (231), Expect = 5e-20
 Identities = 67/214 (31%), Positives = 91/214 (42%), Gaps = 22/214 (10%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           NCTD+DEC+ SP  C  G C+NT GS+ C C   YE      + +   K  C        
Sbjct: 360 NCTDIDECRISPDLCGSGICVNTPGSFECECFEGYE------SGFMMMK-NCMDIDGCER 412

Query: 64  GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQ-LCPGGP-----GYQ 117
               CR    ++ +G+   C C +G       + C +    +    LC  G      G  
Sbjct: 413 NPLLCRGGTCVNTEGSFQ-CDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTY 471

Query: 118 PVLEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                P Y  T       DIDEC    G C    CTN+ GS+ C+C  G++L P      
Sbjct: 472 QCSCNPGYQATPDRQGCTDIDECMIMNGGC-DTQCTNSEGSYECSCSEGYALMPDGRSCA 530

Query: 173 XXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                   PD+C  G C N+PG Y CLC +G++A
Sbjct: 531 DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMA 564



 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 52/159 (32%), Positives = 73/159 (45%), Gaps = 20/159 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C D++EC+S   C  G C N  GS+ C C P  +L S G  C DS K  C+  +      
Sbjct: 98  CEDINECES-NPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNI------ 150

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSY 125
           +  R    ++     + CC ++GAAWG+ C+ C           CP G            
Sbjct: 151 QDSRCEVNINGATLKSECCATLGAAWGSPCERC------ELDTACPRGLA-------RIK 197

Query: 126 VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
            VT  D++EC    G+C +G C N+ GSF C C  G +L
Sbjct: 198 GVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTL 236



 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 61/212 (28%), Positives = 86/212 (40%), Gaps = 16/212 (7%)

Query: 8   DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----CYGKVDL 61
           D++ECK+ P  C YG+C NT GS+ CRC   + L  +   C D  + R     C   + +
Sbjct: 321 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 380

Query: 62  RS-GTETCRDSDELSEDGTMAACCCSVGAAWGN--YCDPCPEPGSEAYRQL-CPGGPGYQ 117
            + G+  C   +       M   C  +     N   C       +E   Q  CP G    
Sbjct: 381 NTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELS 440

Query: 118 PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
           P  E         DI+EC+  + LC +G C N  G++ C+C  G+   P           
Sbjct: 441 PSRED------CVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDEC 494

Query: 178 XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
              +      C N  GSY C C EGY  MP+G
Sbjct: 495 MIMNGGCDTQCTNSEGSYECSCSEGYALMPDG 526



 Score = 87.8 bits (208), Expect = 3e-17
 Identities = 64/217 (29%), Positives = 91/217 (41%), Gaps = 30/217 (13%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           +C D++EC  S   C+ G+C+N  G+Y C C P Y+   D   C D  +        +  
Sbjct: 445 DCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMI-----MNG 499

Query: 64  GTET-CRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLCPGG-----P 114
           G +T C +S+   E      C CS G A    G  C    E   E    +C GG     P
Sbjct: 500 GCDTQCTNSEGSYE------CSCSEGYALMPDGRSCADIDE--CENNPDICDGGQCTNIP 551

Query: 115 GYQPVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX 169
           G    L    ++      T  D++EC  +  +C  G C NT GSF+C C  G+S+     
Sbjct: 552 GEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTT 611

Query: 170 X-XXXXXXXXRPDVCG-PGVCRNLPGSYVCLCPEGYV 204
                         C     C N+PGS+ C C EG++
Sbjct: 612 GCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWI 648



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 59/217 (27%), Positives = 85/217 (39%), Gaps = 25/217 (11%)

Query: 1   MP-GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR---- 54
           MP G +C D+DEC+ +P  C  GQC N  G Y C C   +    D   C D  +      
Sbjct: 523 MPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSN 582

Query: 55  -C-YGKVDLRSGTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPE-PGSEAYR 107
            C +G+ +   G+  C      S       C     C +GA   +    C   PGS  ++
Sbjct: 583 ICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGS--FK 640

Query: 108 QLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAP 166
             C  G             +   D DEC+     C+ +  C NT GS+ C C  G++   
Sbjct: 641 CSCREG--------WIGNGIKCIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGFT-GD 691

Query: 167 XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                         ++C  G C N+PG+Y C C  G+
Sbjct: 692 GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGF 728



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 31/75 (41%), Positives = 39/75 (52%), Gaps = 1/75 (1%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRPDVCGPGVCR 189
           DI+ECA    +CA+G C N  GS+ C C +G+   A                +C  G+CR
Sbjct: 16  DINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCR 75

Query: 190 NLPGSYVCLCPEGYV 204
           N PGSY C CP GYV
Sbjct: 76  NTPGSYSCTCPPGYV 90



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 46/169 (27%), Positives = 68/169 (40%), Gaps = 17/169 (10%)

Query: 6   CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DV+EC  +   C +G+C NT+GS+ C C   Y +    T C D  +           G
Sbjct: 571 CIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEI--------G 622

Query: 65  TETC-RDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSE-AYRQLCPGGPGYQPV 119
              C   +  L+  G+    C       G  C   D C     + +    C   PG    
Sbjct: 623 AHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDRDECSNGTHQCSINAQCVNTPGSYRC 682

Query: 120 LEPPSYV---VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
                +     T +D+DECA +  LC +G C N  G++ C C  G++ A
Sbjct: 683 ACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPA 731



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 29/82 (35%), Positives = 37/82 (45%), Gaps = 1/82 (1%)

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
           EP +      DIDEC  +  LC +G C NT GS+ CTC  G+ +                
Sbjct: 48  EPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGY-VFRTETETCEDINECES 106

Query: 181 DVCGPGVCRNLPGSYVCLCPEG 202
           + C  G CRN  GS+ C C  G
Sbjct: 107 NPCVNGACRNNLGSFNCECSPG 128



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 20/46 (43%), Positives = 28/46 (60%), Gaps = 1/46 (2%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           GF C+DVDEC ++   C+ GQC+N  G+Y C C   +   SD  +C
Sbjct: 692 GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSC 737



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 54/220 (24%), Positives = 74/220 (33%), Gaps = 27/220 (12%)

Query: 8   DVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----------------- 49
           D++EC   P  C  G C N +GSY C C   YE  + G  C D                 
Sbjct: 16  DINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCR 75

Query: 50  ----SRKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEA 105
               S    C      R+ TETC D +E   +  +   C +   ++   C P  +  S  
Sbjct: 76  NTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTG 135

Query: 106 YRQL-CPGGPGYQPVLEPPSYV-VTLADI-DECAAHEGLCAHGTCTNTFGSFVCTCGAGW 162
              +    G  +  + +    V +  A +  EC A  G      C          C  G 
Sbjct: 136 LICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERC--ELDTACPRGL 193

Query: 163 SLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
           +                P VC  G C N  GS+ C CPEG
Sbjct: 194 ARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEG 233


>X62008-1|CAB56534.1|  517|Homo sapiens fibrillin 15 protein.
          Length = 517

 Score =  161 bits (391), Expect = 2e-39
 Identities = 82/204 (40%), Positives = 106/204 (51%), Gaps = 10/204 (4%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C D+DEC+  P  C+ G C+NT+GS+ C+CP    L + G  C D R   C+    L
Sbjct: 109 GTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCF----L 164

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGYQPVL 120
           R   E C  +  ++    M ACCCSVGAAWG   C+ CP   +  Y +LCP GPG+    
Sbjct: 165 RYEDEEC--TLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFA-TK 221

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXR 179
           E  +      DI+EC     LC HG C NT GSF C C +G++L +              
Sbjct: 222 EITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRIS 281

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           PD+CG G C N PG + C C EGY
Sbjct: 282 PDLCGRGQCVNTPGDFECKCDEGY 305



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 67/214 (31%), Positives = 93/214 (43%), Gaps = 22/214 (10%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           NCTD+DEC+ SP  C  GQC+NT G + C+C   YE      + +   K  C    + + 
Sbjct: 271 NCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYE------SGFMMMK-NCMDIDECQR 323

Query: 64  GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS-EAYRQLCPGGP------GY 116
               CR     + +G+   C C  G         C +    E    LCP G        Y
Sbjct: 324 DPLLCRGGVCHNTEGSYR-CECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKY 382

Query: 117 QPVLEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
           Q    P  +         DIDEC+   G C    CTN+ GS+ C+C  G++L P      
Sbjct: 383 QCACNPGYHSTPDRLFCVDIDECSIMNGGC-ETFCTNSEGSYECSCQPGFALMPDQRSCT 441

Query: 173 XXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                   P++C  G C N+PG Y CLC +G++A
Sbjct: 442 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMA 475



 Score = 91.5 bits (217), Expect = 2e-18
 Identities = 63/211 (29%), Positives = 87/211 (41%), Gaps = 21/211 (9%)

Query: 5   NCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----C-YG 57
           NC D+DEC + P  C+ G C NT+GSY C CPP ++L  + +AC D  +       C  G
Sbjct: 314 NCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNG 373

Query: 58  KVDLRSGTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPGG 113
           +     G   C  +           C     CS+       C+        +Y   C   
Sbjct: 374 RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSI---MNGGCETFCTNSEGSYECSCQ-- 428

Query: 114 PGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
           PG+   L P     T  DIDEC  +  +C  G CTN  G + C C  G+  +        
Sbjct: 429 PGF--ALMPDQRSCT--DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVD 484

Query: 174 XXX-XXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P++C  G C N  GS++C C  GY
Sbjct: 485 VNECDLNPNICLSGTCENTKGSFICHCDMGY 515



 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 18/212 (8%)

Query: 8   DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----C-YGKVD 60
           D++ECK  P  C +G+C NT GS+ CRC   + L S+   C D  + R     C  G+  
Sbjct: 232 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 291

Query: 61  LRSGTETCRDSDELSEDG-TMAACCCSVGAAWGN--YCDPCPEPGSE-AYRQLCPGGPGY 116
              G   C+  DE  E G  M   C  +     +   C       +E +YR  CP  PG+
Sbjct: 292 NTPGDFECK-CDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECP--PGH 348

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
           Q  L P   +    DI+EC     LC +G C N  G + C C  G+   P          
Sbjct: 349 Q--LSPN--ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 404

Query: 177 XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
               +      C N  GSY C C  G+  MP+
Sbjct: 405 CSIMNGGCETFCTNSEGSYECSCQPGFALMPD 436



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 53/171 (30%), Positives = 72/171 (42%), Gaps = 24/171 (14%)

Query: 6   CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D++EC+ S   C  G+C+N  G Y C C P Y    D   C D  +        +  G
Sbjct: 357 CIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSI-----MNGG 411

Query: 65  TET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS-EAYRQLCPGG-----PGYQ 117
            ET C +S+   E      C C  G A       C +    E    +C GG     PG  
Sbjct: 412 CETFCTNSEGSYE------CSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEY 465

Query: 118 PVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS 163
             L    ++      T  D++EC  +  +C  GTC NT GSF+C C  G+S
Sbjct: 466 RCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYS 516



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 48/147 (32%), Positives = 64/147 (43%), Gaps = 19/147 (12%)

Query: 18  CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSED 77
           C  G C N+ GS+ C C     L    T C ++ K  C+  V    G    R    ++  
Sbjct: 20  CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTV--IDG----RCEININGA 73

Query: 78  GTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
              + CC S+GAAWG+ C  C          +C  G GY  +           DIDEC  
Sbjct: 74  TLKSQCCSSLGAAWGSPCTLC------QVDPIC--GKGYSRIKG-----TQCEDIDECEV 120

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSL 164
             G+C +G C NT GSF C C +G +L
Sbjct: 121 FPGVCKNGLCVNTRGSFKCQCPSGMTL 147



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 11/25 (44%), Positives = 16/25 (64%)

Query: 142 CAHGTCTNTFGSFVCTCGAGWSLAP 166
           C +G C N+ GSF+C C +  +L P
Sbjct: 20  CINGVCKNSPGSFICECSSESTLDP 44



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 10/17 (58%), Positives = 13/17 (76%)

Query: 183 CGPGVCRNLPGSYVCLC 199
           C  GVC+N PGS++C C
Sbjct: 20  CINGVCKNSPGSFICEC 36


>AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.
          Length = 1365

 Score =  161 bits (391), Expect = 2e-39
 Identities = 82/204 (40%), Positives = 106/204 (51%), Gaps = 10/204 (4%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D+DEC+  P  C+ G C+NT+GS+ C+CP    L + G  C D R   C+    L
Sbjct: 905  GTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCF----L 960

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGYQPVL 120
            R   E C  +  ++    M ACCCSVGAAWG   C+ CP   +  Y +LCP GPG+    
Sbjct: 961  RYEDEEC--TLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFA-TK 1017

Query: 121  EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXR 179
            E  +      DI+EC     LC HG C NT GSF C C +G++L +              
Sbjct: 1018 EITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRIS 1077

Query: 180  PDVCGPGVCRNLPGSYVCLCPEGY 203
            PD+CG G C N PG + C C EGY
Sbjct: 1078 PDLCGRGQCVNTPGDFECKCDEGY 1101



 Score =  137 bits (331), Expect = 3e-32
 Identities = 71/209 (33%), Positives = 102/209 (48%), Gaps = 18/209 (8%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-KARCYGKVDL 61
           G  C D++EC++P  C  G+C+NT GSY C C P   +  DG  C D+  ++ CYG    
Sbjct: 608 GRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYG---- 663

Query: 62  RSGTETCRDSDELSEDGTMAACCC-SVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
             G +  +    L    T + CCC S   A+G  C PCP   S  Y+ LC  GPG     
Sbjct: 664 --GYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAG 721

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXR 179
                    +DI+ECA    +C +G C N  G++ C C +G+ + +              
Sbjct: 722 ---------SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLN 772

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
             +C  G CRN PGS+VC CP+G++  P+
Sbjct: 773 SLLCDNGQCRNTPGSFVCTCPKGFIYKPD 801



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 67/214 (31%), Positives = 93/214 (43%), Gaps = 22/214 (10%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            NCTD+DEC+ SP  C  GQC+NT G + C+C   YE      + +   K  C    + + 
Sbjct: 1067 NCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYE------SGFMMMK-NCMDIDECQR 1119

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS-EAYRQLCPGGP------GY 116
                CR     + +G+   C C  G         C +    E    LCP G        Y
Sbjct: 1120 DPLLCRGGVCHNTEGSYR-CECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKY 1178

Query: 117  QPVLEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
            Q    P  +         DIDEC+   G C    CTN+ GS+ C+C  G++L P      
Sbjct: 1179 QCACNPGYHSTPDRLFCVDIDECSIMNGGC-ETFCTNSEGSYECSCQPGFALMPDQRSCT 1237

Query: 173  XXXX-XXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                    P++C  G C N+PG Y CLC +G++A
Sbjct: 1238 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMA 1271



 Score = 87.4 bits (207), Expect = 4e-17
 Identities = 48/134 (35%), Positives = 60/134 (44%), Gaps = 12/134 (8%)

Query: 79  TMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAH 138
           T   CC +VG AWG+ C+ CP        Q  P   G+ P +   +      D+DEC A 
Sbjct: 205 TKTLCCATVGRAWGHPCEMCPA-------QPHPCRRGFIPNIRTGA----CQDVDECQAI 253

Query: 139 EGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCGPGVCRNLPGSYVC 197
            GLC  G C NT GSF C C AG  L                P +C  G C N   SY C
Sbjct: 254 PGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFC 313

Query: 198 LCPEGYVAMPNGSQ 211
            CP G+   P+G++
Sbjct: 314 KCPPGFYTSPDGTR 327



 Score = 85.4 bits (202), Expect = 1e-16
 Identities = 54/159 (33%), Positives = 72/159 (45%), Gaps = 20/159 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C D+DEC+S   C  G C N+ GS+ C C     L    T C ++ K  C+  V    G 
Sbjct: 805 CEDIDECES-SPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVI--DG- 860

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSY 125
              R    ++     + CC S+GAAWG+ C  C          +C  G GY  +      
Sbjct: 861 ---RCEININGATLKSQCCSSLGAAWGSPCTLC------QVDPIC--GKGYSRIKG---- 905

Query: 126 VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
                DIDEC    G+C +G C NT GSF C C +G +L
Sbjct: 906 -TQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTL 943



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 48/124 (38%), Positives = 61/124 (49%), Gaps = 17/124 (13%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC + P  C+ G+C NT  SY C+CPP +    DGT C D R   CY    L +G
Sbjct: 286 CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCY--TALTNG 343

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW--GNYCDP--CPEPGSEAYRQLC------PGGP 114
               R S++L +  T   CCC  G  W  G    P  CP   +E + +LC      PG P
Sbjct: 344 ----RCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRP 399

Query: 115 GYQP 118
            Y P
Sbjct: 400 EYPP 403



 Score = 83.0 bits (196), Expect = 8e-16
 Identities = 63/214 (29%), Positives = 85/214 (39%), Gaps = 26/214 (12%)

Query: 6    CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C D++EC+ S   C  G+C+N  G Y C C P Y    D   C D  +        +  G
Sbjct: 1153 CIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSI-----MNGG 1207

Query: 65   TET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS-EAYRQLCPGG-----PGYQ 117
             ET C +S+   E      C C  G A       C +    E    +C GG     PG  
Sbjct: 1208 CETFCTNSEGSYE------CSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEY 1261

Query: 118  PVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS-LAPXXXXX 171
              L    ++      T  D++EC  +  +C  GTC NT GSF+C C  G+S         
Sbjct: 1262 RCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321

Query: 172  XXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYV 204
                       CG   VC N  GS+ C C  G++
Sbjct: 1322 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI 1355



 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 18/212 (8%)

Query: 8    DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----C-YGKVD 60
            D++ECK  P  C +G+C NT GS+ CRC   + L S+   C D  + R     C  G+  
Sbjct: 1028 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087

Query: 61   LRSGTETCRDSDELSEDG-TMAACCCSVGAAWGN--YCDPCPEPGSE-AYRQLCPGGPGY 116
               G   C+  DE  E G  M   C  +     +   C       +E +YR  CP  PG+
Sbjct: 1088 NTPGDFECK-CDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECP--PGH 1144

Query: 117  QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
            Q  L P   +    DI+EC     LC +G C N  G + C C  G+   P          
Sbjct: 1145 Q--LSPN--ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1200

Query: 177  XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                +      C N  GSY C C  G+  MP+
Sbjct: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFALMPD 1232



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 49/166 (29%), Positives = 74/166 (44%), Gaps = 21/166 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC+    C  G+CIN QGSYTC+C   Y+     T C D  +    G++      
Sbjct: 488 CIDVDECEK-NPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRI------ 540

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG------PGYQPV 119
             C +   ++ DG+   C C+ G         C +    + R +C  G        ++ +
Sbjct: 541 --CNNGRCINTDGSF-HCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCI 597

Query: 120 LEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
            +P   + +      DI+EC    G+C +G C NT GS+ C C  G
Sbjct: 598 CKPGFQLASDGRYCKDINECET-PGICMNGRCVNTDGSYRCECFPG 642



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 56/194 (28%), Positives = 72/194 (37%), Gaps = 20/194 (10%)

Query: 18  CQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCYGKVDLRS-GTETCRDSDE 73
           CQ G+CI T GS  C C   ++L   G  C D     K  C G   + + G+ TC+    
Sbjct: 460 CQNGRCIPTPGSCRCECNKGFQLDLRG-ECIDVDECEKNPCAGGECINNQGSYTCQCRAG 518

Query: 74  LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG-YQPVLEPPSYVV----T 128
                T   C            D C + G       C    G +  V     +V      
Sbjct: 519 YQSTLTRTEC---------RDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 569

Query: 129 LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVC 188
             D+DEC+    +C +G C N  GSF C C  G+ LA              P +C  G C
Sbjct: 570 CEDMDECSI-RNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRC 628

Query: 189 RNLPGSYVCLCPEG 202
            N  GSY C C  G
Sbjct: 629 VNTDGSYRCECFPG 642



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 36/119 (30%), Positives = 49/119 (41%), Gaps = 8/119 (6%)

Query: 95  CDPCPEPGSEAYRQ----LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNT 150
           C+  P  G E         C    GYQ  L          DIDEC  +  +C +G C NT
Sbjct: 494 CEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTE----CRDIDECLQNGRICNNGRCINT 549

Query: 151 FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            GSF C C AG+ +                ++C  G+C N  GS+ C+C  G+    +G
Sbjct: 550 DGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDG 608



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 22/45 (48%), Positives = 28/45 (62%), Gaps = 1/45 (2%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           C DVDEC++ P  CQ G CINT GS+ C+CP  ++L      C D
Sbjct: 244 CQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCED 288



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           D+DEC  +   CA G C N  GS+ C C AG+ S                  +C  G C 
Sbjct: 490 DVDECEKNP--CAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCI 547

Query: 190 NLPGSYVCLCPEGYVAMPNG 209
           N  GS+ C+C  G+    +G
Sbjct: 548 NTDGSFHCVCNAGFHVTRDG 567



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 5    NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +CTD+DEC+ +P  C  GQC N  G Y C C   +    D   C D  +      + L  
Sbjct: 1235 SCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG 1294

Query: 64   GTETCRDS 71
              E  + S
Sbjct: 1295 TCENTKGS 1302



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 8/57 (14%)

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
           CP G  Y+P L+      T  DIDEC +    C +G C N+ GSF+C C +  +L P
Sbjct: 792 CPKGFIYKPDLK------TCEDIDECESSP--CINGVCKNSPGSFICECSSESTLDP 840


>AK131282-1|BAD18457.1|  872|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16233 fis, clone FEBRA2028256, moderately
           similar to FIBRILLIN 2 PRECURSOR. ).
          Length = 872

 Score =  153 bits (370), Expect = 7e-37
 Identities = 80/209 (38%), Positives = 106/209 (50%), Gaps = 16/209 (7%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  CTD +EC + P  C  G+C+NT GS+ C C   ++     T C+D R+  C+ +V L
Sbjct: 353 GEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV-L 411

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
           ++    CR     SE  T A CCC  G  WG  C+ CP PG+ AYR+LCP G G      
Sbjct: 412 QT---MCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSG------ 462

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRP 180
              Y     D+DEC     LCAHG C N+ GSF C C AG++  A              P
Sbjct: 463 ---YTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP 519

Query: 181 DVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
             C   +C+N  GS++C CP GY+   +G
Sbjct: 520 KPC-TFLCKNTKGSFLCSCPRGYLLEEDG 547



 Score = 85.4 bits (202), Expect = 1e-16
 Identities = 63/212 (29%), Positives = 80/212 (37%), Gaps = 19/212 (8%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARCYGKV 59
           C D+DEC   P+ C +  C NT+GS+ C CP  Y L  DG  C D     SR+  C    
Sbjct: 509 CLDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLC 567

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGYQP 118
               G  TCR     ++       C  V    G + C    +     YR  CP G     
Sbjct: 568 VNTVGAFTCRCPPGFTQH---HQACFDVNECDGPHRCQHGCQNQLGGYRCSCPQG----- 619

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXX 177
                S      D +ECA     C   +C NT G F C C +G+                
Sbjct: 620 -FTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECA 678

Query: 178 XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
            R   C    C N PG ++C CP+GY     G
Sbjct: 679 GRRGPCSYS-CANTPGGFLCGCPQGYFRAGQG 709



 Score = 76.6 bits (180), Expect = 7e-14
 Identities = 66/214 (30%), Positives = 83/214 (38%), Gaps = 24/214 (11%)

Query: 8   DVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           DV+EC ++P  C  G C+NT GS+ C CP  Y L   G  C D+ +      V    G  
Sbjct: 190 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDEC----SVGHPCGQG 245

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCP-EPGSEAYRQLCPGGPGYQPVLEP 122
           TC +       G   AC           C   D C   P   A+R  C    G      P
Sbjct: 246 TCTN----VIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCP 299

Query: 123 PSYVV-----TLADIDECAAHEGLC-AHG-TCTNTFGSFVCTCGAGWSLAPXXXX--XXX 173
             Y +        D+DECA  +  C A G  C N  G+F C C  G    P         
Sbjct: 300 AGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDD 359

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMP 207
                +PD+C  G C N  GS+ C C EG+   P
Sbjct: 360 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSP 393



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 51/167 (30%), Positives = 73/167 (43%), Gaps = 17/167 (10%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA----RCYG 57
           G  C D+DEC S Q +CQ+  C+NT G++TCRCPP +       AC+D  +     RC  
Sbjct: 547 GRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGF--TQHHQACFDVNECDGPHRCQH 603

Query: 58  KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWG-NYCDPCPEPGS-EAYRQLCPGGPG 115
               + G   C      ++    A C      A     C       +   +R +CP G  
Sbjct: 604 GCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFD 663

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGW 162
           +   L          D+DECA   G C++ +C NT G F+C C  G+
Sbjct: 664 FDQALG------GCQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGY 703



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 54/175 (30%), Positives = 65/175 (37%), Gaps = 19/175 (10%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARCYG 57
           G NC D DEC     C  G C N  G + C C   +E        D   C       C  
Sbjct: 227 GINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDEC-SLNPLLCAF 285

Query: 58  KVDLRSGTE--TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CP 111
           +     G+   TC     L EDG M   C  V        D C   G E    +    C 
Sbjct: 286 RCHNTEGSYLCTCPAGYTLREDGAM---CRDVDECADGQQD-CHARGMECKNLIGTFACV 341

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
             PG +P+   P       D +EC A   LC +G C NT GSF C C  G+  +P
Sbjct: 342 CPPGMRPL---PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSP 393



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 123 PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX--XXXRP 180
           P  ++T  DIDEC+ +  LCA   C NT GS++CTC AG++L                + 
Sbjct: 264 PGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQ 322

Query: 181 DVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQ 211
           D    G+ C+NL G++ C+CP G   +P   +
Sbjct: 323 DCHARGMECKNLIGTFACVCPPGMRPLPGSGE 354



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 59/210 (28%), Positives = 80/210 (38%), Gaps = 46/210 (21%)

Query: 8   DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           DVDEC+     C +G+CIN+ GS+ C C   Y    D TA                    
Sbjct: 469 DVDECRMLAHLCAHGECINSLGSFRCHCQAGY--TPDATAT------------------- 507

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYV 126
           TC D DE S+        C      G++   CP               GY  +LE     
Sbjct: 508 TCLDMDECSQVPKPCTFLCK--NTKGSFLCSCPR--------------GY--LLEEDGR- 548

Query: 127 VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
            T  D+DEC + +  C    C NT G+F C C  G++                P  C  G
Sbjct: 549 -TCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFT--QHHQACFDVNECDGPHRCQHG 604

Query: 187 VCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
            C+N  G Y C CP+G+      +Q + +N
Sbjct: 605 -CQNQLGGYRCSCPQGFTQHSQWAQCVDEN 633



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 127 VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
           +   D DEC+     C  GTCTN  G F C C  G+                 P +C   
Sbjct: 228 INCVDTDECSVGHP-CGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR 286

Query: 187 VCRNLPGSYVCLCPEGYVAMPNGS 210
            C N  GSY+C CP GY    +G+
Sbjct: 287 -CHNTEGSYLCTCPAGYTLREDGA 309


>AB208840-1|BAD92077.1|  830|Homo sapiens fibrillin 1 variant
           protein.
          Length = 830

 Score =  147 bits (356), Expect = 3e-35
 Identities = 76/204 (37%), Positives = 103/204 (50%), Gaps = 16/204 (7%)

Query: 6   CTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC + P+ C  G C NT+GS+ C CP  + L S G  C D R + CY K      
Sbjct: 446 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKF----- 500

Query: 65  TETCRDSDELSEDGTMAACCCSV-GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPP 123
            E  + S   S + +   CCC++ G  WG+ C+ CP    EA+RQ+CP G G   ++ P 
Sbjct: 501 -EGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGI--IVGPD 557

Query: 124 SYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC 183
              V   D+DEC   + +C HG C NT GS+ C C  G+ LA              P  C
Sbjct: 558 DSAV---DMDECKEPD-VCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNP--C 611

Query: 184 GPGVCRNLPGSYVCLCPEGYVAMP 207
           G G C+N+ G + C C EG+   P
Sbjct: 612 GNGTCKNVIGGFECTCEEGFEPGP 635



 Score =  136 bits (330), Expect = 5e-32
 Identities = 75/202 (37%), Positives = 98/202 (48%), Gaps = 12/202 (5%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DV+EC++P  C  G C NT G+YTC CPP+Y  V+ G  C D R++ CY   +  +  
Sbjct: 81  CDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYR--NYYADN 138

Query: 66  ETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPG-GPGYQPVLEP 122
           +TC    EL  + T   CCCS  +G AW   C+ CP P ++ +  LC    PG+  V++ 
Sbjct: 139 QTC--DGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGF--VID- 193

Query: 123 PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
             Y     DIDEC    G+C +G C N  GSF C C  G+                   V
Sbjct: 194 -IYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV 252

Query: 183 CGPGV-CRNLPGSYVCLCPEGY 203
           C     C N  GSY C C  GY
Sbjct: 253 CQRNAECINTAGSYRCDCKPGY 274



 Score =  115 bits (277), Expect = 1e-25
 Identities = 52/124 (41%), Positives = 65/124 (52%), Gaps = 4/124 (3%)

Query: 87  VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT 146
           +G AWG  C+ CP   +  Y+ LCPGG G++P   P    V L DIDEC    GLC  G 
Sbjct: 1   LGKAWGTPCEMCPAVNTSEYKILCPGGEGFRP--NP--ITVILEDIDECQELPGLCQGGK 56

Query: 147 CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           C NTFGSF C C  G+ L               P +CGPG C N  G+Y C+CP  Y+ +
Sbjct: 57  CINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQV 116

Query: 207 PNGS 210
             G+
Sbjct: 117 NGGN 120



 Score =  105 bits (253), Expect = 1e-22
 Identities = 66/210 (31%), Positives = 91/210 (43%), Gaps = 23/210 (10%)

Query: 6   CTDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC++   CQ   +CINT GSY C C P Y   S G         +C  + + +  
Sbjct: 241 CEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG---------QCNDRNECQEI 291

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE--- 121
              C     +   G+   C C  G    +    C +  +E  R  C  G     +     
Sbjct: 292 PNICSHGQCIDTVGSFY-CLCHTGFKTNDDQTMCLDI-NECERDACGNGTCRNTIGSFNC 349

Query: 122 --PPSYVVT----LADIDECAAHEG-LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
                ++++      D+DECA+  G LC +G C NT GSF C C  G+ +AP        
Sbjct: 350 RCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDI 409

Query: 175 XX-XXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                 P  C PG C+NL GSY C+CP GY
Sbjct: 410 NECLLEPRKCAPGTCQNLDGSYRCICPPGY 439



 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 72/226 (31%), Positives = 93/226 (41%), Gaps = 28/226 (12%)

Query: 2   PGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           P  +  D+DECK P  C++GQCINT GSY C CP  Y L   G  C D+ +      V  
Sbjct: 556 PDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDEC----SVGN 609

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY--CDPCPE----PGSEAYRQLCPGGPG 115
             G  TC++     E      C C  G   G    C+   E    P   A+R  C    G
Sbjct: 610 PCGNGTCKNVIGGFE------CTCEEGFEPGPMMTCEDINECAQNPLLCAFR--CVNTYG 661

Query: 116 YQPVLEPPSYVV-----TLADIDECAAHEGLCAHG--TCTNTFGSFVCTCGAGWSLAPXX 168
                 P  YV+        D DEC   +  C      C N  G+++C CG G+   P  
Sbjct: 662 SYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDG 721

Query: 169 XX-XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
                      +P +C  G C N  GSY C C +G+ A PN  + L
Sbjct: 722 EGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 767



 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 69/212 (32%), Positives = 91/212 (42%), Gaps = 16/212 (7%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCYGKVD 60
           C D +EC+  P  C +GQCI+T GS+ C C   ++   D T C D     R A   G   
Sbjct: 282 CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCR 341

Query: 61  LRSGTETCRDSDE--LSEDGTMAACC-CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
              G+  CR +    LS +        C+ G   GN C       +    Q C    GY+
Sbjct: 342 NTIGSFNCRCNHGFILSHNNDCIDVDECASGN--GNLCRNGQCINTVGSFQ-CQCNEGYE 398

Query: 118 PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
             + P     T  DI+EC      CA GTC N  GS+ C C  G+SL             
Sbjct: 399 --VAPDGR--TCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL-QNEKCEDIDECV 453

Query: 178 XRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
             P++C  G C N  GS+ CLCPEG+    +G
Sbjct: 454 EEPEICALGTCSNTEGSFKCLCPEGFSLSSSG 485



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 18/176 (10%)

Query: 1   MPGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE-----LVSDGTACYDSRKARC 55
           + G  C D DEC     C  G C N  G + C C   +E        D   C  +     
Sbjct: 594 LAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCA 653

Query: 56  YGKVDLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR----QLC 110
           +  V+     E  C     L ED  M  C        G +   C E   E        +C
Sbjct: 654 FRCVNTYGSYECKCPVGYVLREDRRM--CKDEDECEEGKH--DCTEKQMECKNLIGTYMC 709

Query: 111 PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
             GPGYQ   +    V    D +EC    G+C +G C NT GS+ C C  G++ +P
Sbjct: 710 ICGPGYQRRPDGEGCV----DENECQTKPGICENGRCLNTRGSYTCECNDGFTASP 761



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 59/213 (27%), Positives = 82/213 (38%), Gaps = 25/213 (11%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C D++EC   P+ C  G C N  GSY C CPP Y L ++   C D  +  C  + ++
Sbjct: 403 GRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE--KCEDIDE--CVEEPEI 458

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
                TC +++     G+   C C  G +  +    C +           GG    P   
Sbjct: 459 -CALGTCSNTE-----GSFK-CLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSR 511

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTC----TNTFGSF--VCTCGAGWSLAPXXXXXXXXX 175
             S        + C A +G      C    T    +F  +C  G+G  + P         
Sbjct: 512 NHSKQ------ECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDE 565

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
               PDVC  G C N  GSY C CP GY+   N
Sbjct: 566 CK-EPDVCKHGQCINTDGSYRCECPFGYILAGN 597



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 47/162 (29%), Positives = 71/162 (43%), Gaps = 14/162 (8%)

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAW-GNYC---DPCPEPGSEAYRQLCPGG-PGYQPVL 120
           + C+    ++ DG+   C C  G    GN C   D C   G+      C     G++   
Sbjct: 570 DVCKHGQCINTDGSYR-CECPFGYILAGNECVDTDEC-SVGNPCGNGTCKNVIGGFECTC 627

Query: 121 EP---PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX- 176
           E    P  ++T  DI+ECA +  LCA   C NT+GS+ C C  G+ L             
Sbjct: 628 EEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDEC 686

Query: 177 -XXRPDVCGPGV-CRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
              + D     + C+NL G+Y+C+C  GY   P+G   + +N
Sbjct: 687 EEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDEN 728



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 24/47 (51%), Positives = 29/47 (61%), Gaps = 2/47 (4%)

Query: 5   NCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           +C DVDEC S     C+ GQCINT GS+ C+C   YE+  DG  C D
Sbjct: 362 DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVD 408



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 24/51 (47%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 8  DVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYG 57
          D+DEC+  P  CQ G+CINT GS+ CRCP  Y L  D   C D  +    G
Sbjct: 41 DIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPG 91



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 1/48 (2%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G  C D +EC++ P  C+ G+C+NT+GSYTC C   +    +   C D
Sbjct: 721 GEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLD 768


>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
           protein-4 protein.
          Length = 1587

 Score =  118 bits (285), Expect = 1e-26
 Identities = 72/216 (33%), Positives = 96/216 (44%), Gaps = 15/216 (6%)

Query: 2   PGFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR----CY 56
           PG  C DVDEC +SP  C YG+C NT+GS+ C CP  ++  + G+ C D  +      C 
Sbjct: 709 PGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACP 768

Query: 57  GKVDLRS-GT---ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
           G+  + S G+    TC     L          CS GA     C P     +      C  
Sbjct: 769 GQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAP---PCGPHGHCTNTEGSFRCSC 825

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
            PGY+     P      AD++EC   +    HG C NT GSF CTC  G+   P      
Sbjct: 826 APGYRAPSGRPG---PCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCL 882

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                   D+C  G+C N  GS+ C+CP G+ A P+
Sbjct: 883 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPD 918



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 52/118 (44%), Positives = 67/118 (56%), Gaps = 12/118 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-----KARCYGKV 59
           +C DVDEC +   CQ+G+C NT+G YTC CP  + L S  ++C         K  C+ +V
Sbjct: 317 SCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCF-RV 375

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            LR G   C  S  +  + T   CCCS VG AWG  C  CP  GSE +R++CP GPGY
Sbjct: 376 -LRDG--GC--SLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGY 428



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 68/209 (32%), Positives = 87/209 (41%), Gaps = 15/209 (7%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G +C DVDEC     CQ G C NT GS+ C CPP +    D  +C D  + R  G     
Sbjct: 878  GASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPA--L 935

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSE-AYRQLCPGGPG-YQ 117
             G++ C +S        +  C     A     C   D C E G E    Q C   PG Y+
Sbjct: 936  CGSQRCENSP--GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYR 993

Query: 118  --PVLEP---PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA-PXXXXX 171
              P  +P   P+      D+DEC       AH  C N  GSF C C  G+  A       
Sbjct: 994  CTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV 1053

Query: 172  XXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
                      VCG  +C N+ GS++C+CP
Sbjct: 1054 DVNECETLQGVCGAALCENVEGSFLCVCP 1082



 Score = 95.5 bits (227), Expect = 1e-19
 Identities = 74/222 (33%), Positives = 95/222 (42%), Gaps = 29/222 (13%)

Query: 6    CTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C DV+EC     C  +G+C+NT GS+ C C P Y     G +C D         VD  S 
Sbjct: 839  CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLD---------VDECSE 889

Query: 65   TETCRDSDELSEDGTMAACCCSVGAAWGN---YC---DPCPEPGSEAY-RQLCPGGPG-Y 116
             + C+     + DG+   C C  G   G     C   D C E G      Q C   PG Y
Sbjct: 890  EDLCQSGICTNTDGSFE-CICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 948

Query: 117  QPVLE-PPSYVV----TLADIDECAAH-EGLCAHGTCTNTFGSFVCT--CGAGWSLAPXX 168
            + V +  P Y      T  D+DEC  +   +C    C NT GS+ CT  C  G+   P  
Sbjct: 949  RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 1008

Query: 169  XXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
                      R   CG   VC+NLPGS+ CLC +GY    +G
Sbjct: 1009 GCQDVDECRNR-SFCGAHAVCQNLPGSFQCLCDQGYEGARDG 1049



 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 68/219 (31%), Positives = 89/219 (40%), Gaps = 19/219 (8%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C DVDEC+  P  C  G+C N+ GS+ C C P +        C D  +  C+ +V  
Sbjct: 545 GTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDE--CH-RVPP 601

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCPGGPG 115
                 C ++      G+   C C  G   A  G  C   D C +      R  C   PG
Sbjct: 602 PCDLGRCENTP-----GSFL-CVCPAGYQAAPHGASCQDVDECTQSPGLCGRGGCKNLPG 655

Query: 116 YQPVLEPPSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXX 172
               + P  +  +    D+DECA     C  G C NT GSF C C AG+ S  P      
Sbjct: 656 SFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQD 715

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
                  P  C  G C N  GS+ C+CP G+     GS+
Sbjct: 716 VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSE 754



 Score = 89.8 bits (213), Expect = 7e-18
 Identities = 66/202 (32%), Positives = 83/202 (41%), Gaps = 22/202 (10%)

Query: 13  KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----CY-GKVDLRSGTE 66
           ++PQ C  G+CI+    YTC C   + L   GT C D  + R     C  G+ +   G+ 
Sbjct: 514 RNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSF 573

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWG--NYCD--PCPE-PGSEAYRQLCPGGPGYQPVLE 121
            C         G  AA C  V         CD   C   PGS  +  +CP G  YQ    
Sbjct: 574 RCVCGPGFRA-GPRAAECLDVDECHRVPPPCDLGRCENTPGS--FLCVCPAG--YQAA-- 626

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
              +  +  D+DEC    GLC  G C N  GSF C C AG+                 P 
Sbjct: 627 --PHGASCQDVDECTQSPGLCGRGGCKNLPGSFRCVCPAGF--RGSACEEDVDECAQEPP 682

Query: 182 VCGPGVCRNLPGSYVCLCPEGY 203
            CGPG C N  GS+ C CP G+
Sbjct: 683 PCGPGRCDNTAGSFHCACPAGF 704



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 72/221 (32%), Positives = 91/221 (41%), Gaps = 26/221 (11%)

Query: 8   DVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-AR----C-YGKVD 60
           DVDEC + P  C  G+C NT GS+ C CP  +     G  C D  + AR    C YG+ +
Sbjct: 673 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCE 732

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGPGY 116
              G+  C       +  T  + C  V     +   P  E    PGS   R  CP G   
Sbjct: 733 NTEGSFQCVCPMGF-QPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRT-CPSGHHL 790

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXXXX--XX 173
                   +     D+DEC++    C  HG CTNT GSF C+C  G+  AP         
Sbjct: 791 --------HRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR-APSGRPGPCAD 841

Query: 174 XXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
                  D C P G C N  GS+ C C  GY   P G+  L
Sbjct: 842 VNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCL 882



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 46/142 (32%), Positives = 59/142 (41%), Gaps = 9/142 (6%)

Query: 74   LSEDGTMAACCCSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLAD 131
            L+ + T   CCC+VG  WG+ C    CP   +  Y+ LCP G GY   L P   +    D
Sbjct: 1160 LARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGY---LAPSGDLSLRRD 1216

Query: 132  IDECAA-HEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRPDVCGPGVCR 189
            +DEC    + +C  G C NT   + C C  G+                     C  G C 
Sbjct: 1217 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 1276

Query: 190  NLPGSYVCLCPEGYVAMPNGSQ 211
            N  GSY C C    V   +GSQ
Sbjct: 1277 NTVGSYHCTCEPPLVL--DGSQ 1296



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 43/128 (33%), Positives = 56/128 (43%), Gaps = 19/128 (14%)

Query: 6    CTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYEL-------VSDGTACYDSRKARCYG 57
            C D DEC   + +C+ G+C+NT GSY C C P   L       VS+ +   D     C+ 
Sbjct: 1257 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1316

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
            +V    G +       L    T   CCC  G AWG  C  CP   S+ +  LC       
Sbjct: 1317 EV----GADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC------- 1365

Query: 118  PVLEPPSY 125
             VL PP+Y
Sbjct: 1366 NVLRPPAY 1373



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 34/118 (28%), Positives = 48/118 (40%), Gaps = 8/118 (6%)

Query: 97  PCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVC 156
           P P PG E      P   G +     PS  +       C  +  +C  G C +    + C
Sbjct: 481 PDPRPGPELPLPSIPAWTGPEIPESGPSSGM-------CQRNPQVCGPGRCISRPSGYTC 533

Query: 157 TCGAGWSLAPXXXXXXXXXXXXR-PDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
            C +G+ L+P            R P  C PG C N PGS+ C+C  G+ A P  ++ L
Sbjct: 534 ACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECL 591



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 11/90 (12%)

Query: 79  TMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGP---GYQPVLEPPSYVVTLADIDE 134
           T   CC   G AWG + C  C E    + R   P GP   G++ V        +  D+DE
Sbjct: 270 TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNG------SCEDVDE 323

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
           CA   G C HG C NT G + C C  G+ L
Sbjct: 324 CATG-GRCQHGECANTRGGYTCVCPDGFLL 352



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 1/49 (2%)

Query: 2    PGFNCTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
            PG  C DVDEC++   C  +  C N  GS+ C C   YE   DG  C D
Sbjct: 1006 PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 1054



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 5/57 (8%)

Query: 2    PGFNCTDVDECK--SPQSCQYGQCINTQGSYTC--RCPPNYELVSDGTACYDSRKAR 54
            P   C DVDEC+   P+ C   +C NT GSY C   C P Y+  + G  C D  + R
Sbjct: 962  PEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECR 1017



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 8/84 (9%)

Query: 8    DVDECK--SPQSCQYGQCINTQGSYTCRCPPNYELVS------DGTACYDSRKARCYGKV 59
            DVDEC+    Q C+ G C+NT   Y+C C   Y   +      D   C D   A   G+ 
Sbjct: 1216 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1275

Query: 60   DLRSGTETCRDSDELSEDGTMAAC 83
                G+  C     L  DG+   C
Sbjct: 1276 VNTVGSYHCTCEPPLVLDGSQRRC 1299



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 1/38 (2%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYE 39
            G +C DV+EC++ Q  C    C N +GS+ C CP + E
Sbjct: 1049 GRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 1086



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 6/83 (7%)

Query: 8    DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
            + +EC     C   +C+     +TCRC   Y L     AC D  +       +  + +  
Sbjct: 1496 EAEECGILDGCTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECD-----EAEAASPL 1550

Query: 68   CRDSDELSEDGTMAACCCSVGAA 90
            C ++  L+ DG+   C C  G A
Sbjct: 1551 CVNARCLNTDGSF-RCICRPGFA 1572



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 4/50 (8%)

Query: 6    CTDVDECKSPQS----CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR 51
            C D++EC   ++    C   +C+NT GS+ C C P +        C  +R
Sbjct: 1535 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1584



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 15/37 (40%), Positives = 20/37 (54%)

Query: 127  VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS 163
            V + + DE  A   LC +  C NT GSF C C  G++
Sbjct: 1536 VDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1572



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 12/35 (34%), Positives = 20/35 (57%)

Query: 183 CGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQNL 217
           C  G C N  G Y C+CP+G++   + S  + Q++
Sbjct: 330 CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHV 364



 Score = 31.9 bits (69), Expect = 1.9
 Identities = 18/77 (23%), Positives = 27/77 (35%), Gaps = 5/77 (6%)

Query: 131  DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGP----G 186
            + +EC   +G C +  C      F C C  G+ L                +   P     
Sbjct: 1496 EAEECGILDG-CTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554

Query: 187  VCRNLPGSYVCLCPEGY 203
             C N  GS+ C+C  G+
Sbjct: 1555 RCLNTDGSFRCICRPGF 1571


>AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth
           factor-beta binding protein 4L protein.
          Length = 1624

 Score =  118 bits (283), Expect = 2e-26
 Identities = 72/216 (33%), Positives = 96/216 (44%), Gaps = 15/216 (6%)

Query: 2   PGFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR----CY 56
           PG  C DVDEC +SP  C YG+C NT+GS+ C CP  ++  + G+ C D  +      C 
Sbjct: 746 PGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECENHLACP 805

Query: 57  GKVDLRS-GTETCR---DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
           G+  + S G+  CR       L          CS GA     C P     +      C  
Sbjct: 806 GQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAP---PCGPHGHCTNTEGSFRCSC 862

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
            PGY+     P      AD++EC   +    HG C NT GSF CTC  G+   P      
Sbjct: 863 APGYRAPSGRPG---PCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCL 919

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                   D+C  G+C N  GS+ C+CP G+ A P+
Sbjct: 920 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPD 955



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 52/118 (44%), Positives = 67/118 (56%), Gaps = 12/118 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-----KARCYGKV 59
           +C DVDEC +   CQ+G+C NT+G YTC CP  + L S  ++C         K  C+ +V
Sbjct: 354 SCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCF-RV 412

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            LR G   C  S  +  + T   CCCS VG AWG  C  CP  GSE +R++CP GPGY
Sbjct: 413 -LRDG--GC--SLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGY 465



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 68/209 (32%), Positives = 87/209 (41%), Gaps = 15/209 (7%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G +C DVDEC     CQ G C NT GS+ C CPP +    D  +C D  + R  G     
Sbjct: 915  GASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPA--L 972

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSE-AYRQLCPGGPG-YQ 117
             G++ C +S        +  C     A     C   D C E G E    Q C   PG Y+
Sbjct: 973  CGSQRCENSP--GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYR 1030

Query: 118  --PVLEP---PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA-PXXXXX 171
              P  +P   P+      D+DEC       AH  C N  GSF C C  G+  A       
Sbjct: 1031 CTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV 1090

Query: 172  XXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
                      VCG  +C N+ GS++C+CP
Sbjct: 1091 DVNECETLQGVCGAALCENVEGSFLCVCP 1119



 Score = 95.5 bits (227), Expect = 1e-19
 Identities = 74/222 (33%), Positives = 95/222 (42%), Gaps = 29/222 (13%)

Query: 6    CTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C DV+EC     C  +G+C+NT GS+ C C P Y     G +C D         VD  S 
Sbjct: 876  CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLD---------VDECSE 926

Query: 65   TETCRDSDELSEDGTMAACCCSVGAAWGN---YC---DPCPEPGSEAY-RQLCPGGPG-Y 116
             + C+     + DG+   C C  G   G     C   D C E G      Q C   PG Y
Sbjct: 927  EDLCQSGICTNTDGSFE-CICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 985

Query: 117  QPVLE-PPSYVV----TLADIDECAAH-EGLCAHGTCTNTFGSFVCT--CGAGWSLAPXX 168
            + V +  P Y      T  D+DEC  +   +C    C NT GS+ CT  C  G+   P  
Sbjct: 986  RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 1045

Query: 169  XXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
                      R   CG   VC+NLPGS+ CLC +GY    +G
Sbjct: 1046 GCQDVDECRNR-SFCGAHAVCQNLPGSFQCLCDQGYEGARDG 1086



 Score = 94.7 bits (225), Expect = 2e-19
 Identities = 68/219 (31%), Positives = 89/219 (40%), Gaps = 19/219 (8%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C DVDEC+  P  C  G+C N+ GS+ C C P +        C D  +  C+ +V  
Sbjct: 582 GTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDE--CH-RVPP 638

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCPGGPG 115
                 C ++      G+   C C  G   A  G  C   D C +      R  C   PG
Sbjct: 639 PCDLGRCENTP-----GSFL-CVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPG 692

Query: 116 YQPVLEPPSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXX 172
               + P  +  +    D+DECA     C  G C NT GSF C C AG+ S  P      
Sbjct: 693 SFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQD 752

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
                  P  C  G C N  GS+ C+CP G+     GS+
Sbjct: 753 VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSE 791



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 66/202 (32%), Positives = 83/202 (41%), Gaps = 22/202 (10%)

Query: 13  KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----CY-GKVDLRSGTE 66
           ++PQ C  G+CI+    YTC C   + L   GT C D  + R     C  G+ +   G+ 
Sbjct: 551 RNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSF 610

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWG--NYCD--PCPE-PGSEAYRQLCPGGPGYQPVLE 121
            C         G  AA C  V         CD   C   PGS  +  +CP G  YQ    
Sbjct: 611 RCVCGPGFRA-GPRAAECLDVDECHRVPPPCDLGRCENTPGS--FLCVCPAG--YQAA-- 663

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
              +  +  D+DEC    GLC  G C N  GSF C C AG+                 P 
Sbjct: 664 --PHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--RGSACEEDVDECAQEPP 719

Query: 182 VCGPGVCRNLPGSYVCLCPEGY 203
            CGPG C N  GS+ C CP G+
Sbjct: 720 PCGPGRCDNTAGSFHCACPAGF 741



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 70/220 (31%), Positives = 88/220 (40%), Gaps = 24/220 (10%)

Query: 8   DVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           DVDEC + P  C  G+C NT GS+ C CP  +     G  C D  +         RS   
Sbjct: 710 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECA-------RSPPP 762

Query: 67  TCRDSDELSEDGTMAACCCSVGA---AWGNYCDPCPEPGSEAY--RQLCPGGPGYQPVLE 121
                 E +E      C C +G    A G+ C+   E  +      Q C   PG      
Sbjct: 763 CTYGRCENTEGSFQ--CVCPMGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRA 820

Query: 122 PPS----YVVTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXXXX--XXX 174
            PS    +     D+DEC++    C  HG CTNT GSF C+C  G+  AP          
Sbjct: 821 CPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR-APSGRPGPCADV 879

Query: 175 XXXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
                 D C P G C N  GS+ C C  GY   P G+  L
Sbjct: 880 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCL 919



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 46/142 (32%), Positives = 59/142 (41%), Gaps = 9/142 (6%)

Query: 74   LSEDGTMAACCCSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLAD 131
            L+ + T   CCC+VG  WG+ C    CP   +  Y+ LCP G GY   L P   +    D
Sbjct: 1197 LARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGY---LAPSGDLSLRRD 1253

Query: 132  IDECAA-HEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRPDVCGPGVCR 189
            +DEC    + +C  G C NT   + C C  G+                     C  G C 
Sbjct: 1254 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 1313

Query: 190  NLPGSYVCLCPEGYVAMPNGSQ 211
            N  GSY C C    V   +GSQ
Sbjct: 1314 NTVGSYHCTCEPPLVL--DGSQ 1333



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 43/128 (33%), Positives = 56/128 (43%), Gaps = 19/128 (14%)

Query: 6    CTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYEL-------VSDGTACYDSRKARCYG 57
            C D DEC   + +C+ G+C+NT GSY C C P   L       VS+ +   D     C+ 
Sbjct: 1294 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1353

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
            +V    G +       L    T   CCC  G AWG  C  CP   S+ +  LC       
Sbjct: 1354 EV----GADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC------- 1402

Query: 118  PVLEPPSY 125
             VL PP+Y
Sbjct: 1403 NVLRPPAY 1410



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 11/90 (12%)

Query: 79  TMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGP---GYQPVLEPPSYVVTLADIDE 134
           T   CC   G AWG + C  C E    + R   P GP   G++ V        +  D+DE
Sbjct: 307 TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNG------SCEDVDE 360

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
           CA   G C HG C NT G + C C  G+ L
Sbjct: 361 CATG-GRCQHGECANTRGGYTCVCPDGFLL 389



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 1/80 (1%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR-PDVCGPGVCRNLPG 193
           C  +  +C  G C +    + C C +G+ L+P            R P  C PG C N PG
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 608

Query: 194 SYVCLCPEGYVAMPNGSQYL 213
           S+ C+C  G+ A P  ++ L
Sbjct: 609 SFRCVCGPGFRAGPRAAECL 628



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 1/49 (2%)

Query: 2    PGFNCTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
            PG  C DVDEC++   C  +  C N  GS+ C C   YE   DG  C D
Sbjct: 1043 PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 1091



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 5/57 (8%)

Query: 2    PGFNCTDVDECK--SPQSCQYGQCINTQGSYTC--RCPPNYELVSDGTACYDSRKAR 54
            P   C DVDEC+   P+ C   +C NT GSY C   C P Y+  + G  C D  + R
Sbjct: 999  PEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECR 1054



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 8    DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
            + +EC     C  G+C+     +TCRC   Y L     AC D  +       +  + +  
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECD-----EAEAASPL 1587

Query: 68   CRDSDELSEDGTMAACCCSVGAA 90
            C ++  L+ DG+   C C  G A
Sbjct: 1588 CVNARCLNTDGSF-RCICRPGFA 1609



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 8/84 (9%)

Query: 8    DVDECK--SPQSCQYGQCINTQGSYTCRCPPNYELVS------DGTACYDSRKARCYGKV 59
            DVDEC+    Q C+ G C+NT   Y+C C   Y   +      D   C D   A   G+ 
Sbjct: 1253 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1312

Query: 60   DLRSGTETCRDSDELSEDGTMAAC 83
                G+  C     L  DG+   C
Sbjct: 1313 VNTVGSYHCTCEPPLVLDGSQRRC 1336



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 1/38 (2%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYE 39
            G +C DV+EC++ Q  C    C N +GS+ C CP + E
Sbjct: 1086 GRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 1123



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 4/50 (8%)

Query: 6    CTDVDECKSPQS----CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR 51
            C D++EC   ++    C   +C+NT GS+ C C P +        C  +R
Sbjct: 1572 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1621



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 15/37 (40%), Positives = 20/37 (54%)

Query: 127  VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS 163
            V + + DE  A   LC +  C NT GSF C C  G++
Sbjct: 1573 VDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1609



 Score = 34.7 bits (76), Expect = 0.27
 Identities = 19/77 (24%), Positives = 28/77 (36%), Gaps = 5/77 (6%)

Query: 131  DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGP----G 186
            + +EC   +G C +G C      F C C  G+ L                +   P     
Sbjct: 1533 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591

Query: 187  VCRNLPGSYVCLCPEGY 203
             C N  GS+ C+C  G+
Sbjct: 1592 RCLNTDGSFRCICRPGF 1608



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 12/35 (34%), Positives = 20/35 (57%)

Query: 183 CGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQNL 217
           C  G C N  G Y C+CP+G++   + S  + Q++
Sbjct: 367 CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHV 401


>AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth
           factor-beta binding protein 4S protein.
          Length = 1557

 Score =  118 bits (283), Expect = 2e-26
 Identities = 72/216 (33%), Positives = 96/216 (44%), Gaps = 15/216 (6%)

Query: 2   PGFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR----CY 56
           PG  C DVDEC +SP  C YG+C NT+GS+ C CP  ++  + G+ C D  +      C 
Sbjct: 679 PGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECENHLACP 738

Query: 57  GKVDLRS-GTETCR---DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
           G+  + S G+  CR       L          CS GA     C P     +      C  
Sbjct: 739 GQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAP---PCGPHGHCTNTEGSFRCSC 795

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
            PGY+     P      AD++EC   +    HG C NT GSF CTC  G+   P      
Sbjct: 796 APGYRAPSGRPG---PCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCL 852

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                   D+C  G+C N  GS+ C+CP G+ A P+
Sbjct: 853 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPD 888



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 52/118 (44%), Positives = 67/118 (56%), Gaps = 12/118 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR-----KARCYGKV 59
           +C DVDEC +   CQ+G+C NT+G YTC CP  + L S  ++C         K  C+ +V
Sbjct: 287 SCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCF-RV 345

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            LR G   C  S  +  + T   CCCS VG AWG  C  CP  GSE +R++CP GPGY
Sbjct: 346 -LRDG--GC--SLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGY 398



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 68/209 (32%), Positives = 87/209 (41%), Gaps = 15/209 (7%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            G +C DVDEC     CQ G C NT GS+ C CPP +    D  +C D  + R  G     
Sbjct: 848  GASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPA--L 905

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSE-AYRQLCPGGPG-YQ 117
             G++ C +S        +  C     A     C   D C E G E    Q C   PG Y+
Sbjct: 906  CGSQRCENSP--GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYR 963

Query: 118  --PVLEP---PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA-PXXXXX 171
              P  +P   P+      D+DEC       AH  C N  GSF C C  G+  A       
Sbjct: 964  CTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV 1023

Query: 172  XXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
                      VCG  +C N+ GS++C+CP
Sbjct: 1024 DVNECETLQGVCGAALCENVEGSFLCVCP 1052



 Score = 95.5 bits (227), Expect = 1e-19
 Identities = 74/222 (33%), Positives = 95/222 (42%), Gaps = 29/222 (13%)

Query: 6    CTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
            C DV+EC     C  +G+C+NT GS+ C C P Y     G +C D         VD  S 
Sbjct: 809  CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLD---------VDECSE 859

Query: 65   TETCRDSDELSEDGTMAACCCSVGAAWGN---YC---DPCPEPGSEAY-RQLCPGGPG-Y 116
             + C+     + DG+   C C  G   G     C   D C E G      Q C   PG Y
Sbjct: 860  EDLCQSGICTNTDGSFE-CICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 918

Query: 117  QPVLE-PPSYVV----TLADIDECAAH-EGLCAHGTCTNTFGSFVCT--CGAGWSLAPXX 168
            + V +  P Y      T  D+DEC  +   +C    C NT GS+ CT  C  G+   P  
Sbjct: 919  RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 978

Query: 169  XXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
                      R   CG   VC+NLPGS+ CLC +GY    +G
Sbjct: 979  GCQDVDECRNR-SFCGAHAVCQNLPGSFQCLCDQGYEGARDG 1019



 Score = 94.7 bits (225), Expect = 2e-19
 Identities = 68/219 (31%), Positives = 89/219 (40%), Gaps = 19/219 (8%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C DVDEC+  P  C  G+C N+ GS+ C C P +        C D  +  C+ +V  
Sbjct: 515 GTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDE--CH-RVPP 571

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCPGGPG 115
                 C ++      G+   C C  G   A  G  C   D C +      R  C   PG
Sbjct: 572 PCDLGRCENTP-----GSFL-CVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPG 625

Query: 116 YQPVLEPPSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXX 172
               + P  +  +    D+DECA     C  G C NT GSF C C AG+ S  P      
Sbjct: 626 SFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQD 685

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
                  P  C  G C N  GS+ C+CP G+     GS+
Sbjct: 686 VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSE 724



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 66/202 (32%), Positives = 83/202 (41%), Gaps = 22/202 (10%)

Query: 13  KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-----CY-GKVDLRSGTE 66
           ++PQ C  G+CI+    YTC C   + L   GT C D  + R     C  G+ +   G+ 
Sbjct: 484 RNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSF 543

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWG--NYCD--PCPE-PGSEAYRQLCPGGPGYQPVLE 121
            C         G  AA C  V         CD   C   PGS  +  +CP G  YQ    
Sbjct: 544 RCVCGPGFRA-GPRAAECLDVDECHRVPPPCDLGRCENTPGS--FLCVCPAG--YQAA-- 596

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
              +  +  D+DEC    GLC  G C N  GSF C C AG+                 P 
Sbjct: 597 --PHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--RGSACEEDVDECAQEPP 652

Query: 182 VCGPGVCRNLPGSYVCLCPEGY 203
            CGPG C N  GS+ C CP G+
Sbjct: 653 PCGPGRCDNTAGSFHCACPAGF 674



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 70/220 (31%), Positives = 88/220 (40%), Gaps = 24/220 (10%)

Query: 8   DVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           DVDEC + P  C  G+C NT GS+ C CP  +     G  C D  +         RS   
Sbjct: 643 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECA-------RSPPP 695

Query: 67  TCRDSDELSEDGTMAACCCSVGA---AWGNYCDPCPEPGSEAY--RQLCPGGPGYQPVLE 121
                 E +E      C C +G    A G+ C+   E  +      Q C   PG      
Sbjct: 696 CTYGRCENTEGSFQ--CVCPMGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRA 753

Query: 122 PPS----YVVTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXXXX--XXX 174
            PS    +     D+DEC++    C  HG CTNT GSF C+C  G+  AP          
Sbjct: 754 CPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR-APSGRPGPCADV 812

Query: 175 XXXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
                 D C P G C N  GS+ C C  GY   P G+  L
Sbjct: 813 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCL 852



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 46/142 (32%), Positives = 59/142 (41%), Gaps = 9/142 (6%)

Query: 74   LSEDGTMAACCCSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLAD 131
            L+ + T   CCC+VG  WG+ C    CP   +  Y+ LCP G GY   L P   +    D
Sbjct: 1130 LARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGY---LAPSGDLSLRRD 1186

Query: 132  IDECAA-HEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRPDVCGPGVCR 189
            +DEC    + +C  G C NT   + C C  G+                     C  G C 
Sbjct: 1187 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 1246

Query: 190  NLPGSYVCLCPEGYVAMPNGSQ 211
            N  GSY C C    V   +GSQ
Sbjct: 1247 NTVGSYHCTCEPPLVL--DGSQ 1266



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 43/128 (33%), Positives = 56/128 (43%), Gaps = 19/128 (14%)

Query: 6    CTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYEL-------VSDGTACYDSRKARCYG 57
            C D DEC   + +C+ G+C+NT GSY C C P   L       VS+ +   D     C+ 
Sbjct: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1286

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
            +V    G +       L    T   CCC  G AWG  C  CP   S+ +  LC       
Sbjct: 1287 EV----GADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC------- 1335

Query: 118  PVLEPPSY 125
             VL PP+Y
Sbjct: 1336 NVLRPPAY 1343



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 11/90 (12%)

Query: 79  TMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGP---GYQPVLEPPSYVVTLADIDE 134
           T   CC   G AWG + C  C E    + R   P GP   G++ V        +  D+DE
Sbjct: 240 TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNG------SCEDVDE 293

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
           CA   G C HG C NT G + C C  G+ L
Sbjct: 294 CATG-GRCQHGECANTRGGYTCVCPDGFLL 322



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 1/80 (1%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR-PDVCGPGVCRNLPG 193
           C  +  +C  G C +    + C C +G+ L+P            R P  C PG C N PG
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541

Query: 194 SYVCLCPEGYVAMPNGSQYL 213
           S+ C+C  G+ A P  ++ L
Sbjct: 542 SFRCVCGPGFRAGPRAAECL 561



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 1/49 (2%)

Query: 2    PGFNCTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
            PG  C DVDEC++   C  +  C N  GS+ C C   YE   DG  C D
Sbjct: 976  PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 1024



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 5/57 (8%)

Query: 2   PGFNCTDVDECK--SPQSCQYGQCINTQGSYTC--RCPPNYELVSDGTACYDSRKAR 54
           P   C DVDEC+   P+ C   +C NT GSY C   C P Y+  + G  C D  + R
Sbjct: 932 PEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECR 987



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 8    DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
            + +EC     C  G+C+     +TCRC   Y L     AC D  +       +  + +  
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECD-----EAEAASPL 1520

Query: 68   CRDSDELSEDGTMAACCCSVGAA 90
            C ++  L+ DG+   C C  G A
Sbjct: 1521 CVNARCLNTDGSF-RCICRPGFA 1542



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 8/84 (9%)

Query: 8    DVDECK--SPQSCQYGQCINTQGSYTCRCPPNYELVS------DGTACYDSRKARCYGKV 59
            DVDEC+    Q C+ G C+NT   Y+C C   Y   +      D   C D   A   G+ 
Sbjct: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1245

Query: 60   DLRSGTETCRDSDELSEDGTMAAC 83
                G+  C     L  DG+   C
Sbjct: 1246 VNTVGSYHCTCEPPLVLDGSQRRC 1269



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 1/38 (2%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYE 39
            G +C DV+EC++ Q  C    C N +GS+ C CP + E
Sbjct: 1019 GRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 1056



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 4/50 (8%)

Query: 6    CTDVDECKSPQS----CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR 51
            C D++EC   ++    C   +C+NT GS+ C C P +        C  +R
Sbjct: 1505 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 15/37 (40%), Positives = 20/37 (54%)

Query: 127  VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS 163
            V + + DE  A   LC +  C NT GSF C C  G++
Sbjct: 1506 VDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1542



 Score = 34.7 bits (76), Expect = 0.27
 Identities = 19/77 (24%), Positives = 28/77 (36%), Gaps = 5/77 (6%)

Query: 131  DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGP----G 186
            + +EC   +G C +G C      F C C  G+ L                +   P     
Sbjct: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524

Query: 187  VCRNLPGSYVCLCPEGY 203
             C N  GS+ C+C  G+
Sbjct: 1525 RCLNTDGSFRCICRPGF 1541



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 12/35 (34%), Positives = 20/35 (57%)

Query: 183 CGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQNL 217
           C  G C N  G Y C+CP+G++   + S  + Q++
Sbjct: 300 CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHV 334


>BC008761-1|AAH08761.2|  743|Homo sapiens LTBP3 protein protein.
          Length = 743

 Score =  115 bits (276), Expect = 2e-25
 Identities = 71/207 (34%), Positives = 88/207 (42%), Gaps = 15/207 (7%)

Query: 3   GFNCTDVDEC-KSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCY 56
           G  C D+DEC + P  C  +G C N QGSY C C   +    D   C +      K  CY
Sbjct: 348 GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECY 407

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD--PCPEPGSEAYRQLCPGGP 114
              D    T  C DS  L+ + T   CCCS+GA WG++C+  PCP   S  +  LCP G 
Sbjct: 408 LNFD---DTVFC-DS-VLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGK 462

Query: 115 GYQPVLEPPSY-VVTLADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
           GY       +Y +    DIDEC      +C  G C NT   + C C  G+          
Sbjct: 463 GYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECV 522

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                     C  GVC N  G Y C C
Sbjct: 523 DVDECLDESNCRNGVCENTRGGYRCAC 549



 Score = 98.7 bits (235), Expect = 1e-20
 Identities = 73/211 (34%), Positives = 94/211 (44%), Gaps = 19/211 (9%)

Query: 3   GFNCTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYEL-VSDGTACYDSRKAR----CY 56
           G +C D++EC  P  C   G CIN  G Y C C P Y L  S    C D  + R    C 
Sbjct: 142 GRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCP 201

Query: 57  -GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP--CPE-PGSEAYRQLCPG 112
            GK + + G+  C             AC      A G+ C P  C   PGS  +R  C  
Sbjct: 202 DGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGS--FRCTC-- 257

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
             GY P  +  S +    D+DEC A + +C +G C+NT GSF C C +G+ L+       
Sbjct: 258 AQGYAPAPDGRSCL----DVDECEAGD-VCDNGICSNTPGSFQCQCLSGYHLSRDRSHCE 312

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  C  G C N  GSY CLCP+G+
Sbjct: 313 DIDECDFPAACIGGDCINTNGSYRCLCPQGH 343



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 70/211 (33%), Positives = 86/211 (40%), Gaps = 26/211 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTC-RCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC+ P SC  G+C N  GS+ C  C P Y     G AC D  +  C        G
Sbjct: 188 CEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGG-ACRDVNE--CAEGSPCSPG 244

Query: 65  TETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCPGGPGYQP 118
              C +       G+   C C+ G   A  G  C   D C E G      +C   PG   
Sbjct: 245 W--CENLP-----GSFR-CTCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQ 295

Query: 119 VLEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                 Y ++       DIDEC      C  G C NT GS+ C C  G  L         
Sbjct: 296 CQCLSGYHLSRDRSHCEDIDECD-FPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDI 354

Query: 174 XXXXXRPDVCGP-GVCRNLPGSYVCLCPEGY 203
                 P +C P G C+NL GSYVC+C EG+
Sbjct: 355 DECSQDPSLCLPHGACKNLQGSYVCVCDEGF 385



 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 68/214 (31%), Positives = 88/214 (41%), Gaps = 28/214 (13%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYEL--VSDGTACYDSRKARCYGKVDLR 62
           C DV+EC++ P     G C+NT GSY C C   Y L   + G +C D  +          
Sbjct: 101 CVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC--------- 151

Query: 63  SGTETCRDSDELSEDGTMAACCCSVG----AAWGNYC---DPCPEPGSEAYRQLCPGGPG 115
           +    C D            C C  G    A+    C   D C +P S      C   PG
Sbjct: 152 AKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDP-SSCPDGKCENKPG 210

Query: 116 -YQPVLEPPSYVV----TLADIDECAAHEGL-CAHGTCTNTFGSFVCTCGAGWSLAPXXX 169
            ++ +   P Y         D++ECA  EG  C+ G C N  GSF CTC  G++ AP   
Sbjct: 211 SFKCIACQPGYRSQGGGACRDVNECA--EGSPCSPGWCENLPGSFRCTCAQGYAPAPDGR 268

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      DVC  G+C N PGS+ C C  GY
Sbjct: 269 SCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGY 302



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 64/224 (28%), Positives = 86/224 (38%), Gaps = 27/224 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-ARCYGKVDL--- 61
           C DVDEC    +C+ G C NT+G Y C C P  E       C    +  R   + D+   
Sbjct: 521 CVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWS 580

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG------ 115
           + G +            T   CCC  G  WG  C PCP  G+ ++   CP          
Sbjct: 581 QRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSH---CPTSQSESNSFW 637

Query: 116 -YQPVL--EPP-SYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL----APX 167
              P+L  +PP     +  D DEC      C  G C    G  VC C  G+ L    A  
Sbjct: 638 DTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARC 692

Query: 168 XXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV-AMPNGS 210
                      R  +C    C N  GS+ C+C  G+  + P+G+
Sbjct: 693 VDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGA 736



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 63/223 (28%), Positives = 85/223 (38%), Gaps = 27/223 (12%)

Query: 7   TDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           T+ DEC+  Q+ C +G+C+     Y+C C P Y        C D  +  C  +     G 
Sbjct: 60  TETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNE--CEAE-PCGPGR 116

Query: 66  ETCRDSDELSEDGTMAACCCSVG-----AAWGNYC---DPCPEPGSEAYRQLCPGGPGYQ 117
             C ++      G    C C+ G      A G  C   + C +P        C   PG+ 
Sbjct: 117 GICMNT------GGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHY 170

Query: 118 PVLEPPSYVVTLA------DIDECAAHEGLCAHGTCTNTFGSFVC-TCGAGWSLAPXXXX 170
                P Y +  +      DIDEC      C  G C N  GSF C  C  G+  +     
Sbjct: 171 KCNCYPGYRLKASRPPVCEDIDEC-RDPSSCPDGKCENKPGSFKCIACQPGYR-SQGGGA 228

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
                       C PG C NLPGS+ C C +GY   P+G   L
Sbjct: 229 CRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCL 271



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 23/45 (51%), Positives = 27/45 (60%), Gaps = 1/45 (2%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           +C D+DEC  P +C  G CINT GSY C CP  + LV  G  C D
Sbjct: 310 HCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG-GRKCQD 353



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 5/112 (4%)

Query: 94  YCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGS 153
           Y +    P     R   P  P  +  +E     VT  + DEC  ++ +C HG C      
Sbjct: 26  YPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVT--ETDECRLNQNICGHGECVPGPPD 83

Query: 154 FVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGP--GVCRNLPGSYVCLCPEGY 203
           + C C  G+   P              + CGP  G+C N  GSY C C  GY
Sbjct: 84  YSCHCNPGYRSHP-QHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGY 134



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 4/51 (7%)

Query: 6   CTDVDECKSPQS----CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK 52
           C D+DEC+        C+  +C+NT GS+ C C   +       AC   R+
Sbjct: 692 CVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRR 742


>AL117551-1|CAB55988.1|  511|Homo sapiens hypothetical protein
           protein.
          Length = 511

 Score =  115 bits (276), Expect = 2e-25
 Identities = 71/207 (34%), Positives = 88/207 (42%), Gaps = 15/207 (7%)

Query: 3   GFNCTDVDEC-KSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCY 56
           G  C D+DEC + P  C  +G C N QGSY C C   +    D   C +      K  CY
Sbjct: 69  GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECY 128

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD--PCPEPGSEAYRQLCPGGP 114
              D    T  C DS  L+ + T   CCCS+GA WG++C+  PCP   S  +  LCP G 
Sbjct: 129 LNFD---DTVFC-DS-VLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGK 183

Query: 115 GYQPVLEPPSY-VVTLADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
           GY       +Y +    DIDEC      +C  G C NT   + C C  G+          
Sbjct: 184 GYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECV 243

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                     C  GVC N  G Y C C
Sbjct: 244 DVDECLDESNCRNGVCENTRGGYRCAC 270



 Score = 83.0 bits (196), Expect = 8e-16
 Identities = 65/223 (29%), Positives = 90/223 (40%), Gaps = 28/223 (12%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY--DSRKARCYGKVDL---R 62
           DVDEC+ P +C+ G+C+N  GSY C C P +     G  C   +S   R   + D+   +
Sbjct: 290 DVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQ 349

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG------- 115
            G +            T   CCC  G  WG  C PCP  G+ ++   CP           
Sbjct: 350 RGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSH---CPTSQSESNSFWD 406

Query: 116 YQPVL--EPP-SYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL----APXX 168
             P+L  +PP     +  D DEC      C  G C    G  VC C  G+ L    A   
Sbjct: 407 TSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCV 461

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV-AMPNGS 210
                     R  +C    C N  GS+ C+C  G+  + P+G+
Sbjct: 462 DIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGA 504



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 31/74 (41%), Positives = 36/74 (48%), Gaps = 2/74 (2%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGP-GVCR 189
           DIDEC      C  G C NT GS+ C C  G  L               P +C P G C+
Sbjct: 34  DIDECD-FPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACK 92

Query: 190 NLPGSYVCLCPEGY 203
           NL GSYVC+C EG+
Sbjct: 93  NLQGSYVCVCDEGF 106



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 23/45 (51%), Positives = 27/45 (60%), Gaps = 1/45 (2%)

Query: 5  NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
          +C D+DEC  P +C  G CINT GSY C CP  + LV  G  C D
Sbjct: 31 HCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG-GRKCQD 74



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 25/63 (39%), Positives = 33/63 (52%)

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
           +C +G C+NT GSF C C +G+ L+              P  C  G C N  GSY CLCP
Sbjct: 2   VCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCP 61

Query: 201 EGY 203
           +G+
Sbjct: 62  QGH 64



 Score = 46.4 bits (105), Expect = 8e-05
 Identities = 53/215 (24%), Positives = 68/215 (31%), Gaps = 22/215 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC    +C+ G C NT+G Y C C P  E       C    +      VD     
Sbjct: 242 CVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEM----DVDECQDP 297

Query: 66  ETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEA--YRQLCPGGPGYQPVLE 121
             CR    ++  G+    C    V    G  C     P   A   R +C    G   +  
Sbjct: 298 AACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCA 357

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTC----TNTFGSFVCT----CGAGWSLAPXXXXXXX 173
            P     L   D+C   +G      C        GS   T      + W  +P       
Sbjct: 358 GPLAGPALT-FDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPP 416

Query: 174 XXXXXRPD-----VCGPGVCRNLPGSYVCLCPEGY 203
                  +      C  G C   PG  VC CP G+
Sbjct: 417 RDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGF 451



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 4/51 (7%)

Query: 6   CTDVDECKSPQS----CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK 52
           C D+DEC+        C+  +C+NT GS+ C C   +       AC   R+
Sbjct: 460 CVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRR 510



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 13/23 (56%), Positives = 15/23 (65%)

Query: 181 DVCGPGVCRNLPGSYVCLCPEGY 203
           DVC  G+C N PGS+ C C  GY
Sbjct: 1   DVCDNGICSNTPGSFQCQCLSGY 23



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 42/165 (25%), Positives = 60/165 (36%), Gaps = 29/165 (17%)

Query: 18  CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCYGKVDLRS---------- 63
           C  G C NT GS+ C+C   Y L  D + C D  +    A C G   + +          
Sbjct: 3   CDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQ 62

Query: 64  -----GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                G   C+D DE S+D ++     +     G+Y   C E  +    Q      G + 
Sbjct: 63  GHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQ-----HGCEE 117

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGTCTN-TFGSFVCTCGAGW 162
           V +P        + D+       C     TN T     C+ GAGW
Sbjct: 118 VEQPHHKKECYLNFDDTV----FCDSVLATNVTQQECCCSLGAGW 158


>AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.
          Length = 1382

 Score =  115 bits (276), Expect = 2e-25
 Identities = 71/207 (34%), Positives = 88/207 (42%), Gaps = 15/207 (7%)

Query: 3    GFNCTDVDEC-KSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCY 56
            G  C D+DEC + P  C  +G C N QGSY C C   +    D   C +      K  CY
Sbjct: 940  GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECY 999

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD--PCPEPGSEAYRQLCPGGP 114
               D    T  C DS  L+ + T   CCCS+GA WG++C+  PCP   S  +  LCP G 
Sbjct: 1000 LNFD---DTVFC-DS-VLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGK 1054

Query: 115  GYQPVLEPPSY-VVTLADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
            GY       +Y +    DIDEC      +C  G C NT   + C C  G+          
Sbjct: 1055 GYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECV 1114

Query: 173  XXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                      C  GVC N  G Y C C
Sbjct: 1115 DVDECLDESNCRNGVCENTRGGYRCAC 1141



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 45/115 (39%), Positives = 62/115 (53%), Gaps = 8/115 (6%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR---KARCYGKVDL 61
           +C D++EC  P  C++G C+N  GSY C CPP + L    T C   +   K+ C+  V  
Sbjct: 431 HCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLV-- 488

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            S    C+    L+   T   CCCSVG AWG  C  CP  G+ A++++CP G GY
Sbjct: 489 -SPEHQCQHP--LTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGY 540



 Score = 98.7 bits (235), Expect = 1e-20
 Identities = 73/211 (34%), Positives = 94/211 (44%), Gaps = 19/211 (9%)

Query: 3   GFNCTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYEL-VSDGTACYDSRKAR----CY 56
           G +C D++EC  P  C   G CIN  G Y C C P Y L  S    C D  + R    C 
Sbjct: 734 GRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCP 793

Query: 57  -GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP--CPE-PGSEAYRQLCPG 112
            GK + + G+  C             AC      A G+ C P  C   PGS  +R  C  
Sbjct: 794 DGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGS--FRCTC-- 849

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
             GY P  +  S +    D+DEC A + +C +G C+NT GSF C C +G+ L+       
Sbjct: 850 AQGYAPAPDGRSCL----DVDECEAGD-VCDNGICSNTPGSFQCQCLSGYHLSRDRSHCE 904

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  C  G C N  GSY CLCP+G+
Sbjct: 905 DIDECDFPAACIGGDCINTNGSYRCLCPQGH 935



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 70/211 (33%), Positives = 86/211 (40%), Gaps = 26/211 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTC-RCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC+ P SC  G+C N  GS+ C  C P Y     G AC D  +  C        G
Sbjct: 780 CEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGG-ACRDVNE--CAEGSPCSPG 836

Query: 65  TETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCPGGPGYQP 118
              C +       G+   C C+ G   A  G  C   D C E G      +C   PG   
Sbjct: 837 W--CENLP-----GSFR-CTCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQ 887

Query: 119 VLEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                 Y ++       DIDEC      C  G C NT GS+ C C  G  L         
Sbjct: 888 CQCLSGYHLSRDRSHCEDIDECD-FPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDI 946

Query: 174 XXXXXRPDVCGP-GVCRNLPGSYVCLCPEGY 203
                 P +C P G C+NL GSYVC+C EG+
Sbjct: 947 DECSQDPSLCLPHGACKNLQGSYVCVCDEGF 977



 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 68/214 (31%), Positives = 88/214 (41%), Gaps = 28/214 (13%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYEL--VSDGTACYDSRKARCYGKVDLR 62
           C DV+EC++ P     G C+NT GSY C C   Y L   + G +C D  +          
Sbjct: 693 CVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC--------- 743

Query: 63  SGTETCRDSDELSEDGTMAACCCSVG----AAWGNYC---DPCPEPGSEAYRQLCPGGPG 115
           +    C D            C C  G    A+    C   D C +P S      C   PG
Sbjct: 744 AKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDP-SSCPDGKCENKPG 802

Query: 116 -YQPVLEPPSYVV----TLADIDECAAHEGL-CAHGTCTNTFGSFVCTCGAGWSLAPXXX 169
            ++ +   P Y         D++ECA  EG  C+ G C N  GSF CTC  G++ AP   
Sbjct: 803 SFKCIACQPGYRSQGGGACRDVNECA--EGSPCSPGWCENLPGSFRCTCAQGYAPAPDGR 860

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      DVC  G+C N PGS+ C C  GY
Sbjct: 861 SCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGY 894



 Score = 83.0 bits (196), Expect = 8e-16
 Identities = 65/223 (29%), Positives = 90/223 (40%), Gaps = 28/223 (12%)

Query: 8    DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY--DSRKARCYGKVDL---R 62
            DVDEC+ P +C+ G+C+N  GSY C C P +     G  C   +S   R   + D+   +
Sbjct: 1161 DVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQ 1220

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG------- 115
             G +            T   CCC  G  WG  C PCP  G+ ++   CP           
Sbjct: 1221 RGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSH---CPTSQSESNSFWD 1277

Query: 116  YQPVL--EPP-SYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL----APXX 168
              P+L  +PP     +  D DEC      C  G C    G  VC C  G+ L    A   
Sbjct: 1278 TSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCV 1332

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV-AMPNGS 210
                      R  +C    C N  GS+ C+C  G+  + P+G+
Sbjct: 1333 DIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGA 1375



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 63/223 (28%), Positives = 85/223 (38%), Gaps = 27/223 (12%)

Query: 7   TDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           T+ DEC+  Q+ C +G+C+     Y+C C P Y        C D  +  C  +     G 
Sbjct: 652 TETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNE--CEAE-PCGPGR 708

Query: 66  ETCRDSDELSEDGTMAACCCSVG-----AAWGNYC---DPCPEPGSEAYRQLCPGGPGYQ 117
             C ++      G    C C+ G      A G  C   + C +P        C   PG+ 
Sbjct: 709 GICMNT------GGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHY 762

Query: 118 PVLEPPSYVVTLA------DIDECAAHEGLCAHGTCTNTFGSFVC-TCGAGWSLAPXXXX 170
                P Y +  +      DIDEC      C  G C N  GSF C  C  G+  +     
Sbjct: 763 KCNCYPGYRLKASRPPVCEDIDEC-RDPSSCPDGKCENKPGSFKCIACQPGYR-SQGGGA 820

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
                       C PG C NLPGS+ C C +GY   P+G   L
Sbjct: 821 CRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCL 863



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 23/45 (51%), Positives = 27/45 (60%), Gaps = 1/45 (2%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           +C D+DEC  P +C  G CINT GSY C CP  + LV  G  C D
Sbjct: 902 HCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG-GRKCQD 945



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 33/90 (36%), Positives = 43/90 (47%), Gaps = 9/90 (10%)

Query: 83  CCCSVGAAWG-NYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTL-----ADIDECA 136
           CC S+G AWG + C  CP+      ++  PG    +   + P     L      DI+ECA
Sbjct: 382 CCGSIGTAWGQSKCHKCPQLQYTGVQK--PGPVRGEVGADCPQGYKRLNSTHCQDINECA 439

Query: 137 AHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              G+C HG C N  GS+ C C  G SL P
Sbjct: 440 M-PGVCRHGDCLNNPGSYRCVCPPGHSLGP 468



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 5/112 (4%)

Query: 94  YCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGS 153
           Y +    P     R   P  P  +  +E     VT  + DEC  ++ +C HG C      
Sbjct: 618 YPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVT--ETDECRLNQNICGHGECVPGPPD 675

Query: 154 FVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGP--GVCRNLPGSYVCLCPEGY 203
           + C C  G+   P              + CGP  G+C N  GSY C C  GY
Sbjct: 676 YSCHCNPGYRSHP-QHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGY 726



 Score = 46.4 bits (105), Expect = 8e-05
 Identities = 53/215 (24%), Positives = 68/215 (31%), Gaps = 22/215 (10%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C DVDEC    +C+ G C NT+G Y C C P  E       C    +      VD     
Sbjct: 1113 CVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEM----DVDECQDP 1168

Query: 66   ETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEA--YRQLCPGGPGYQPVLE 121
              CR    ++  G+    C    V    G  C     P   A   R +C    G   +  
Sbjct: 1169 AACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCA 1228

Query: 122  PPSYVVTLADIDECAAHEGLCAHGTC----TNTFGSFVCT----CGAGWSLAPXXXXXXX 173
             P     L   D+C   +G      C        GS   T      + W  +P       
Sbjct: 1229 GPLAGPALT-FDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPP 1287

Query: 174  XXXXXRPD-----VCGPGVCRNLPGSYVCLCPEGY 203
                   +      C  G C   PG  VC CP G+
Sbjct: 1288 RDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGF 1322



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 16/32 (50%), Positives = 20/32 (62%)

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
           P VC  G C N PGSY C+CP G+   P+ +Q
Sbjct: 441 PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 472



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 4/51 (7%)

Query: 6    CTDVDECKSPQS----CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK 52
            C D+DEC+        C+  +C+NT GS+ C C   +       AC   R+
Sbjct: 1331 CVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRR 1381


>AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming growth
            factor beta binding protein 3 protein.
          Length = 1256

 Score =  115 bits (276), Expect = 2e-25
 Identities = 71/207 (34%), Positives = 88/207 (42%), Gaps = 15/207 (7%)

Query: 3    GFNCTDVDEC-KSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCY 56
            G  C D+DEC + P  C  +G C N QGSY C C   +    D   C +      K  CY
Sbjct: 861  GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECY 920

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD--PCPEPGSEAYRQLCPGGP 114
               D    T  C DS  L+ + T   CCCS+GA WG++C+  PCP   S  +  LCP G 
Sbjct: 921  LNFD---DTVFC-DS-VLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGK 975

Query: 115  GYQPVLEPPSY-VVTLADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
            GY       +Y +    DIDEC      +C  G C NT   + C C  G+          
Sbjct: 976  GYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECV 1035

Query: 173  XXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                      C  GVC N  G Y C C
Sbjct: 1036 DVDECLDESNCRNGVCENTRGGYRCAC 1062



 Score = 99.5 bits (237), Expect = 8e-21
 Identities = 45/115 (39%), Positives = 62/115 (53%), Gaps = 8/115 (6%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR---KARCYGKVDL 61
           +C D++EC  P  C++G C+N  GSY C CPP + L    T C   +   K+ C+  V  
Sbjct: 352 HCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLV-- 409

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            S    C+    L+   T   CCCSVG AWG  C  CP  G+ A++++CP G GY
Sbjct: 410 -SPEHQCQHP--LTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGY 461



 Score = 98.7 bits (235), Expect = 1e-20
 Identities = 73/211 (34%), Positives = 94/211 (44%), Gaps = 19/211 (9%)

Query: 3   GFNCTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYEL-VSDGTACYDSRKAR----CY 56
           G +C D++EC  P  C   G CIN  G Y C C P Y L  S    C D  + R    C 
Sbjct: 655 GRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCP 714

Query: 57  -GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP--CPE-PGSEAYRQLCPG 112
            GK + + G+  C             AC      A G+ C P  C   PGS  +R  C  
Sbjct: 715 DGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGS--FRCTC-- 770

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
             GY P  +  S +    D+DEC A + +C +G C+NT GSF C C +G+ L+       
Sbjct: 771 AQGYAPAPDGRSCL----DVDECEAGD-VCDNGICSNTPGSFQCQCLSGYHLSRDRSHCE 825

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P  C  G C N  GSY CLCP+G+
Sbjct: 826 DIDECDFPAACIGGDCINTNGSYRCLCPQGH 856



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 70/211 (33%), Positives = 86/211 (40%), Gaps = 26/211 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTC-RCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC+ P SC  G+C N  GS+ C  C P Y     G AC D  +  C        G
Sbjct: 701 CEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGG-ACRDVNE--CAEGSPCSPG 757

Query: 65  TETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCPGGPGYQP 118
              C +       G+   C C+ G   A  G  C   D C E G      +C   PG   
Sbjct: 758 W--CENLP-----GSFR-CTCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQ 808

Query: 119 VLEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                 Y ++       DIDEC      C  G C NT GS+ C C  G  L         
Sbjct: 809 CQCLSGYHLSRDRSHCEDIDECD-FPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDI 867

Query: 174 XXXXXRPDVCGP-GVCRNLPGSYVCLCPEGY 203
                 P +C P G C+NL GSYVC+C EG+
Sbjct: 868 DECSQDPSLCLPHGACKNLQGSYVCVCDEGF 898



 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 68/214 (31%), Positives = 88/214 (41%), Gaps = 28/214 (13%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYEL--VSDGTACYDSRKARCYGKVDLR 62
           C DV+EC++ P     G C+NT GSY C C   Y L   + G +C D  +          
Sbjct: 614 CVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC--------- 664

Query: 63  SGTETCRDSDELSEDGTMAACCCSVG----AAWGNYC---DPCPEPGSEAYRQLCPGGPG 115
           +    C D            C C  G    A+    C   D C +P S      C   PG
Sbjct: 665 AKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDP-SSCPDGKCENKPG 723

Query: 116 -YQPVLEPPSYVV----TLADIDECAAHEGL-CAHGTCTNTFGSFVCTCGAGWSLAPXXX 169
            ++ +   P Y         D++ECA  EG  C+ G C N  GSF CTC  G++ AP   
Sbjct: 724 SFKCIACQPGYRSQGGGACRDVNECA--EGSPCSPGWCENLPGSFRCTCAQGYAPAPDGR 781

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      DVC  G+C N PGS+ C C  GY
Sbjct: 782 SCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGY 815



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 64/224 (28%), Positives = 86/224 (38%), Gaps = 27/224 (12%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-ARCYGKVDL--- 61
            C DVDEC    +C+ G C NT+G Y C C P  E       C    +  R   + D+   
Sbjct: 1034 CVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWS 1093

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG------ 115
            + G +            T   CCC  G  WG  C PCP  G+ ++   CP          
Sbjct: 1094 QRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSH---CPTSQSESNSFW 1150

Query: 116  -YQPVL--EPP-SYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL----APX 167
               P+L  +PP     +  D DEC      C  G C    G  VC C  G+ L    A  
Sbjct: 1151 DTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARC 1205

Query: 168  XXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV-AMPNGS 210
                       R  +C    C N  GS+ C+C  G+  + P+G+
Sbjct: 1206 VDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGA 1249



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 63/223 (28%), Positives = 85/223 (38%), Gaps = 27/223 (12%)

Query: 7   TDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           T+ DEC+  Q+ C +G+C+     Y+C C P Y        C D  +  C  +     G 
Sbjct: 573 TETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNE--CEAE-PCGPGR 629

Query: 66  ETCRDSDELSEDGTMAACCCSVG-----AAWGNYC---DPCPEPGSEAYRQLCPGGPGYQ 117
             C ++      G    C C+ G      A G  C   + C +P        C   PG+ 
Sbjct: 630 GICMNT------GGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHY 683

Query: 118 PVLEPPSYVVTLA------DIDECAAHEGLCAHGTCTNTFGSFVC-TCGAGWSLAPXXXX 170
                P Y +  +      DIDEC      C  G C N  GSF C  C  G+  +     
Sbjct: 684 KCNCYPGYRLKASRPPVCEDIDEC-RDPSSCPDGKCENKPGSFKCIACQPGYR-SQGGGA 741

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
                       C PG C NLPGS+ C C +GY   P+G   L
Sbjct: 742 CRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCL 784



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 23/45 (51%), Positives = 27/45 (60%), Gaps = 1/45 (2%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           +C D+DEC  P +C  G CINT GSY C CP  + LV  G  C D
Sbjct: 823 HCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG-GRKCQD 866



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 33/90 (36%), Positives = 43/90 (47%), Gaps = 9/90 (10%)

Query: 83  CCCSVGAAWG-NYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTL-----ADIDECA 136
           CC S+G AWG + C  CP+      ++  PG    +   + P     L      DI+ECA
Sbjct: 303 CCGSIGTAWGQSKCHKCPQLQYTGVQK--PGPVRGEVGADCPQGYKRLNSTHCQDINECA 360

Query: 137 AHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
              G+C HG C N  GS+ C C  G SL P
Sbjct: 361 M-PGVCRHGDCLNNPGSYRCVCPPGHSLGP 389



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 5/112 (4%)

Query: 94  YCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGS 153
           Y +    P     R   P  P  +  +E     VT  + DEC  ++ +C HG C      
Sbjct: 539 YPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVT--ETDECRLNQNICGHGECVPGPPD 596

Query: 154 FVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGP--GVCRNLPGSYVCLCPEGY 203
           + C C  G+   P              + CGP  G+C N  GSY C C  GY
Sbjct: 597 YSCHCNPGYRSHP-QHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGY 647



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 16/32 (50%), Positives = 20/32 (62%)

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
           P VC  G C N PGSY C+CP G+   P+ +Q
Sbjct: 362 PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 4/51 (7%)

Query: 6    CTDVDECKSPQS----CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK 52
            C D+DEC+        C+  +C+NT GS+ C C   +       AC   R+
Sbjct: 1205 CVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRR 1255


>M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.
          Length = 1394

 Score =  107 bits (256), Expect = 4e-23
 Identities = 71/213 (33%), Positives = 87/213 (40%), Gaps = 22/213 (10%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC DVDEC  P  C  G C+NT G++ C  C   Y +   G  C D         +D 
Sbjct: 625 GTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG-RCED---------IDE 674

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVG-AAWGNYC---DPCPEPGSEAYRQLCPGGPGYQ 117
                TC D   ++  G+     C+ G   W   C   D C EP   A    C    G  
Sbjct: 675 CLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSY 733

Query: 118 PVLEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  Y  T       DIDEC     LC +G C NT GSF CTCG G+ L+       
Sbjct: 734 MCSCHKGYTRTPDHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCE 792

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                    +C  G CRN  GS+ C+C +GY A
Sbjct: 793 DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRA 825



 Score = 97.1 bits (231), Expect = 5e-20
 Identities = 67/217 (30%), Positives = 92/217 (42%), Gaps = 23/217 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           +C D+DEC+    C  GQC NT+GS+ C C   Y+L +    C D         +D    
Sbjct: 749 HCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED---------IDECQH 799

Query: 65  TETCRDSDELSEDGTMAACCCSVG---AAWGNYCD---PCPEPGSEAYRQLCPGGPGYQP 118
              C      + +G+   C C  G   +  G++C+    C E  S   R  C    G   
Sbjct: 800 RHLCAHGQCRNTEGSF-QCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD 858

Query: 119 VLEPPSYVV----TLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P  + +    T  DI+EC  H GLC   G C NT GSF C C  G+S++        
Sbjct: 859 CTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCED 917

Query: 174 XXXXXRPDVC-GPGVCRNLPGSYVCLCPEGYVAMPNG 209
                   VC   G C N  GS+ CLC +G+ A  +G
Sbjct: 918 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDG 954



 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 64/215 (29%), Positives = 85/215 (39%), Gaps = 22/215 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC  P  C  G C N +GSY C C   Y    D   C D         +D     
Sbjct: 709 CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRD---------IDECQQG 759

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP------GYQPV 119
             C +    + +G+   C C  G       D C +     +R LC  G        +Q V
Sbjct: 760 NLCVNGQCKNTEGSF-RCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCV 818

Query: 120 LEPPSYVVTLA----DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            +       L     DI+EC   + +C  G C NT GS+ CTC  G+ L           
Sbjct: 819 CDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDIN 877

Query: 176 XXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
               P +CGP G C N  GS+ C+C +G+    +G
Sbjct: 878 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 912



 Score = 95.5 bits (227), Expect = 1e-19
 Identities = 64/214 (29%), Positives = 88/214 (41%), Gaps = 18/214 (8%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C DV+EC+     C    C N +GS+ C C    +  S  T    SR +     VD+
Sbjct: 954  GQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDL-DVDV 1012

Query: 62   RSGTETCRD-----------SDELSEDGTMAACCCSVGAAWGNYCD--PCPEPGSEAYRQ 108
                E  ++            + L+ + T   CCC+ GA WG+ C+  PCP  G+  + +
Sbjct: 1013 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE 1072

Query: 109  LCPGGPGYQPVLEPPSYV--VTLADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLA 165
            +CP G G+ P  E  S        D DEC    + +C +G C NT   + C C  G    
Sbjct: 1073 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 1132

Query: 166  PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
            P             P  C  G C N  GSY C C
Sbjct: 1133 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 1166



 Score = 93.9 bits (223), Expect = 4e-19
 Identities = 63/208 (30%), Positives = 90/208 (43%), Gaps = 21/208 (10%)

Query: 6   CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC   Q  C  G+C NT+GS+ C CP  +    +GT C D         VD    
Sbjct: 586 CVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCID---------VDECLR 636

Query: 65  TETCRDSDELSEDGTMAACCCSVG--AAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQ- 117
            + C +   ++  G      C  G        C   D C  P S    + C   PG YQ 
Sbjct: 637 PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNP-STCPDEQCVNSPGSYQC 695

Query: 118 -PVLEP-PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            P  E    +     D+DEC     +CA+G C+N  GS++C+C  G++  P         
Sbjct: 696 VPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDID 754

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
              + ++C  G C+N  GS+ C C +GY
Sbjct: 755 ECQQGNLCVNGQCKNTEGSFRCTCGQGY 782



 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 74/256 (28%), Positives = 104/256 (40%), Gaps = 42/256 (16%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS-G 64
            C D+DEC+ P SC  GQC+NT+GSY C C   + +V D +     R A    +++     
Sbjct: 1138 CFDMDECQDPSSCIDGQCVNTEGSYNCFC--THPMVLDASEKRCIRPAESNEQIEETDVY 1195

Query: 65   TETCRD--SDE-------LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC----- 110
             + C +  SDE       + +  T   CCC  G AWG  C  CP   S+ Y QLC     
Sbjct: 1196 QDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVT 1255

Query: 111  ----PGG--------PGYQPVLEP----PSYVVTLADI--DECAAHEGLCAHGTCTNTFG 152
                P G          Y P  +P      ++ +  ++  +EC    G C +G C     
Sbjct: 1256 GRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CENGRCVRVQE 1314

Query: 153  SFVCTCGAGWSLAPXXXX----XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
             + C C  G+ L                  R  +C    C N  GSY CLC  GYV  P+
Sbjct: 1315 GYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV--PS 1372

Query: 209  GSQYLLQNLSTNMRLK 224
                    L+T + L+
Sbjct: 1373 DKPNYCTPLNTALNLE 1388



 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 44/117 (37%), Positives = 58/117 (49%), Gaps = 12/117 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCP------PNYELVSDGTACYDSRKARCYGKV 59
           C D++EC+    C  G+C+NT GSY C C       P +             K  CY  V
Sbjct: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLV 357

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
              SG +       LS   T   CCCSVG A G +C+ CP PG+ A++++CPGG GY
Sbjct: 358 S--SGRQCMYP---LSVHLTKQLCCCSVGKA-GPHCEKCPLPGTAAFKEICPGGMGY 408



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 60/208 (28%), Positives = 84/208 (40%), Gaps = 22/208 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C D+DEC+    C +GQC NT+GS+ C C   Y     G  C D  +  C          
Sbjct: 791 CEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE--CL------EDK 842

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNY--C---DPCPEPGSEAYRQLCPGGPGYQPVL 120
             C+  D ++  G+   C C  G    +   C   + C  PG    +  C    G    +
Sbjct: 843 SVCQRGDCINTAGSYD-CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCV 901

Query: 121 EPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               + +     T  DIDEC  +    +HG C NT GSF C C  G+  AP         
Sbjct: 902 CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ-APQDGQGCVDV 960

Query: 176 XXXR--PDVCGPGVCRNLPGSYVCLCPE 201
                   VCG   C N+ GS++C+C +
Sbjct: 961 NECELLSGVCGEAFCENVEGSFLCVCAD 988



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 52/169 (30%), Positives = 70/169 (41%), Gaps = 24/169 (14%)

Query: 3   GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C D++EC   +S CQ G CINT GSY C CP  ++L  D   C D  +    G    
Sbjct: 829 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPGLCGP 887

Query: 62  RS---GTE-----TCRDSDELSEDGTMAACCCSVGAAWGN-YCDP---CPEPGSEAYRQL 109
           +     TE      C+    +S DG     C  +     N  CD    C      ++R L
Sbjct: 888 QGECLNTEGSFHCVCQQGFSISADGRT---CEDIDECVNNTVCDSHGFCDNTAG-SFRCL 943

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTC 158
           C  G       + P       D++EC    G+C    C N  GSF+C C
Sbjct: 944 CYQG------FQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 986



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 8/86 (9%)

Query: 83  CCCSVGAAWG-NYCDPCPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
           CC +VG +WG N C  CP+ P    Y Q+    PGY+ V           DI+EC   +G
Sbjct: 255 CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN-----TFCQDINECQL-QG 308

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAP 166
           +C +G C NT GS+ CTC  G+   P
Sbjct: 309 VCPNGECLNTMGSYRCTCKIGFGPDP 334



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 129 LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD-VCGPGV 187
           + +I+EC  +  +C  G C N    + C C  G+  +             +   +C  G 
Sbjct: 544 VTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR 603

Query: 188 CRNLPGSYVCLCPEGYVAMPNGS 210
           C N  GS++C+CP G++A   G+
Sbjct: 604 CENTEGSFLCICPAGFMASEEGT 626



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 7/96 (7%)

Query: 4    FNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            F     +EC     C+ G+C+  Q  YTC C   Y L +    C+D  +       +L +
Sbjct: 1290 FEELQAEECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECD-----ELNN 1344

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDP 97
                C+++  ++ DG+    C    V +   NYC P
Sbjct: 1345 RMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTP 1380


>BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming growth
           factor beta binding protein 1 protein.
          Length = 1395

 Score =  107 bits (256), Expect = 4e-23
 Identities = 71/213 (33%), Positives = 87/213 (40%), Gaps = 22/213 (10%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC DVDEC  P  C  G C+NT G++ C  C   Y +   G  C D         +D 
Sbjct: 626 GTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG-RCED---------IDE 675

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVG-AAWGNYC---DPCPEPGSEAYRQLCPGGPGYQ 117
                TC D   ++  G+     C+ G   W   C   D C EP   A    C    G  
Sbjct: 676 CLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSY 734

Query: 118 PVLEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  Y  T       DIDEC     LC +G C NT GSF CTCG G+ L+       
Sbjct: 735 MCSCHKGYTRTPDHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCE 793

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                    +C  G CRN  GS+ C+C +GY A
Sbjct: 794 DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRA 826



 Score = 97.1 bits (231), Expect = 5e-20
 Identities = 67/217 (30%), Positives = 92/217 (42%), Gaps = 23/217 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           +C D+DEC+    C  GQC NT+GS+ C C   Y+L +    C D         +D    
Sbjct: 750 HCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED---------IDECQH 800

Query: 65  TETCRDSDELSEDGTMAACCCSVG---AAWGNYCD---PCPEPGSEAYRQLCPGGPGYQP 118
              C      + +G+   C C  G   +  G++C+    C E  S   R  C    G   
Sbjct: 801 RHLCAHGQCRNTEGSF-QCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD 859

Query: 119 VLEPPSYVV----TLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P  + +    T  DI+EC  H GLC   G C NT GSF C C  G+S++        
Sbjct: 860 CTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCED 918

Query: 174 XXXXXRPDVC-GPGVCRNLPGSYVCLCPEGYVAMPNG 209
                   VC   G C N  GS+ CLC +G+ A  +G
Sbjct: 919 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDG 955



 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 64/215 (29%), Positives = 85/215 (39%), Gaps = 22/215 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC  P  C  G C N +GSY C C   Y    D   C D         +D     
Sbjct: 710 CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRD---------IDECQQG 760

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP------GYQPV 119
             C +    + +G+   C C  G       D C +     +R LC  G        +Q V
Sbjct: 761 NLCVNGQCKNTEGSF-RCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCV 819

Query: 120 LEPPSYVVTLA----DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            +       L     DI+EC   + +C  G C NT GS+ CTC  G+ L           
Sbjct: 820 CDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDIN 878

Query: 176 XXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
               P +CGP G C N  GS+ C+C +G+    +G
Sbjct: 879 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 913



 Score = 95.5 bits (227), Expect = 1e-19
 Identities = 64/214 (29%), Positives = 88/214 (41%), Gaps = 18/214 (8%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C DV+EC+     C    C N +GS+ C C    +  S  T    SR +     VD+
Sbjct: 955  GQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDL-DVDV 1013

Query: 62   RSGTETCRD-----------SDELSEDGTMAACCCSVGAAWGNYCD--PCPEPGSEAYRQ 108
                E  ++            + L+ + T   CCC+ GA WG+ C+  PCP  G+  + +
Sbjct: 1014 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE 1073

Query: 109  LCPGGPGYQPVLEPPSYV--VTLADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLA 165
            +CP G G+ P  E  S        D DEC    + +C +G C NT   + C C  G    
Sbjct: 1074 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 1133

Query: 166  PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
            P             P  C  G C N  GSY C C
Sbjct: 1134 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 1167



 Score = 93.9 bits (223), Expect = 4e-19
 Identities = 45/117 (38%), Positives = 59/117 (50%), Gaps = 11/117 (9%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCP------PNYELVSDGTACYDSRKARCYGKV 59
           C D++EC+    C  G+C+NT GSY C C       P +             K  CY  V
Sbjct: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLV 357

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
              SG +       LS   T   CCCSVG AWG +C+ CP PG+ A++++CPGG GY
Sbjct: 358 S--SGRQCMHP---LSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGY 409



 Score = 93.9 bits (223), Expect = 4e-19
 Identities = 63/208 (30%), Positives = 90/208 (43%), Gaps = 21/208 (10%)

Query: 6   CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC   Q  C  G+C NT+GS+ C CP  +    +GT C D         VD    
Sbjct: 587 CVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCID---------VDECLR 637

Query: 65  TETCRDSDELSEDGTMAACCCSVG--AAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQ- 117
            + C +   ++  G      C  G        C   D C  P S    + C   PG YQ 
Sbjct: 638 PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNP-STCPDEQCVNSPGSYQC 696

Query: 118 -PVLEP-PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            P  E    +     D+DEC     +CA+G C+N  GS++C+C  G++  P         
Sbjct: 697 VPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDID 755

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
              + ++C  G C+N  GS+ C C +GY
Sbjct: 756 ECQQGNLCVNGQCKNTEGSFRCTCGQGY 783



 Score = 89.0 bits (211), Expect = 1e-17
 Identities = 74/256 (28%), Positives = 104/256 (40%), Gaps = 42/256 (16%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS-G 64
            C D+DEC+ P SC  GQC+NT+GSY C C   + +V D +     R A    +++     
Sbjct: 1139 CFDMDECQDPSSCIDGQCVNTEGSYNCFC--THPMVLDASEKRCIRPAESNEQIEETDVY 1196

Query: 65   TETCRD--SDE-------LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC----- 110
             + C +  SDE       + +  T   CCC  G AWG  C  CP   S+ Y QLC     
Sbjct: 1197 QDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVT 1256

Query: 111  ----PGG--------PGYQPVLEP----PSYVVTLADI--DECAAHEGLCAHGTCTNTFG 152
                P G          Y P  +P      ++ +  ++  +EC    G C +G C     
Sbjct: 1257 GRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CENGRCVRVQE 1315

Query: 153  SFVCTCGAGWSLAPXXXX----XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
             + C C  G+ L                  R  +C    C N  GSY CLC  GYV  P+
Sbjct: 1316 GYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV--PS 1373

Query: 209  GSQYLLQNLSTNMRLK 224
                    L+T + L+
Sbjct: 1374 DKPNYCTPLNTALNLE 1389



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 60/208 (28%), Positives = 84/208 (40%), Gaps = 22/208 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C D+DEC+    C +GQC NT+GS+ C C   Y     G  C D  +  C          
Sbjct: 792 CEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE--CL------EDK 843

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNY--C---DPCPEPGSEAYRQLCPGGPGYQPVL 120
             C+  D ++  G+   C C  G    +   C   + C  PG    +  C    G    +
Sbjct: 844 SVCQRGDCINTAGSYD-CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCV 902

Query: 121 EPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               + +     T  DIDEC  +    +HG C NT GSF C C  G+  AP         
Sbjct: 903 CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ-APQDGQGCVDV 961

Query: 176 XXXR--PDVCGPGVCRNLPGSYVCLCPE 201
                   VCG   C N+ GS++C+C +
Sbjct: 962 NECELLSGVCGEAFCENVEGSFLCVCAD 989



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 52/169 (30%), Positives = 70/169 (41%), Gaps = 24/169 (14%)

Query: 3   GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C D++EC   +S CQ G CINT GSY C CP  ++L  D   C D  +    G    
Sbjct: 830 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPGLCGP 888

Query: 62  RS---GTE-----TCRDSDELSEDGTMAACCCSVGAAWGN-YCDP---CPEPGSEAYRQL 109
           +     TE      C+    +S DG     C  +     N  CD    C      ++R L
Sbjct: 889 QGECLNTEGSFHCVCQQGFSISADGRT---CEDIDECVNNTVCDSHGFCDNTAG-SFRCL 944

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTC 158
           C  G       + P       D++EC    G+C    C N  GSF+C C
Sbjct: 945 CYQG------FQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 987



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 8/86 (9%)

Query: 83  CCCSVGAAWG-NYCDPCPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
           CC +VG +WG N C  CP+ P    Y Q+    PGY+ V           DI+EC   +G
Sbjct: 255 CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN-----TFCQDINECQL-QG 308

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAP 166
           +C +G C NT GS+ CTC  G+   P
Sbjct: 309 VCPNGECLNTMGSYRCTCKIGFGPDP 334



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 129 LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD-VCGPGV 187
           + +I+EC  +  +C  G C N    + C C  G+  +             +   +C  G 
Sbjct: 545 VTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR 604

Query: 188 CRNLPGSYVCLCPEGYVAMPNGS 210
           C N  GS++C+CP G++A   G+
Sbjct: 605 CENTEGSFLCICPAGFMASEEGT 627



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 7/96 (7%)

Query: 4    FNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            F     +EC     C+ G+C+  Q  YTC C   Y L +    C D  +       +L +
Sbjct: 1291 FEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECD-----ELNN 1345

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDP 97
                C+++  ++ DG+    C    V +   NYC P
Sbjct: 1346 RMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTP 1381


>AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth
           factor-beta binding protein-1S protein.
          Length = 1394

 Score =  107 bits (256), Expect = 4e-23
 Identities = 71/213 (33%), Positives = 87/213 (40%), Gaps = 22/213 (10%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC DVDEC  P  C  G C+NT G++ C  C   Y +   G  C D         +D 
Sbjct: 625 GTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG-RCED---------IDE 674

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVG-AAWGNYC---DPCPEPGSEAYRQLCPGGPGYQ 117
                TC D   ++  G+     C+ G   W   C   D C EP   A    C    G  
Sbjct: 675 CLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSY 733

Query: 118 PVLEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  Y  T       DIDEC     LC +G C NT GSF CTCG G+ L+       
Sbjct: 734 MCSCHKGYTRTPDHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCE 792

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                    +C  G CRN  GS+ C+C +GY A
Sbjct: 793 DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRA 825



 Score = 97.1 bits (231), Expect = 5e-20
 Identities = 67/217 (30%), Positives = 92/217 (42%), Gaps = 23/217 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           +C D+DEC+    C  GQC NT+GS+ C C   Y+L +    C D         +D    
Sbjct: 749 HCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED---------IDECQH 799

Query: 65  TETCRDSDELSEDGTMAACCCSVG---AAWGNYCD---PCPEPGSEAYRQLCPGGPGYQP 118
              C      + +G+   C C  G   +  G++C+    C E  S   R  C    G   
Sbjct: 800 RHLCAHGQCRNTEGSF-QCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD 858

Query: 119 VLEPPSYVV----TLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P  + +    T  DI+EC  H GLC   G C NT GSF C C  G+S++        
Sbjct: 859 CTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCED 917

Query: 174 XXXXXRPDVC-GPGVCRNLPGSYVCLCPEGYVAMPNG 209
                   VC   G C N  GS+ CLC +G+ A  +G
Sbjct: 918 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDG 954



 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 64/215 (29%), Positives = 85/215 (39%), Gaps = 22/215 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC  P  C  G C N +GSY C C   Y    D   C D         +D     
Sbjct: 709 CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRD---------IDECQQG 759

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP------GYQPV 119
             C +    + +G+   C C  G       D C +     +R LC  G        +Q V
Sbjct: 760 NLCVNGQCKNTEGSF-RCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCV 818

Query: 120 LEPPSYVVTLA----DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            +       L     DI+EC   + +C  G C NT GS+ CTC  G+ L           
Sbjct: 819 CDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDIN 877

Query: 176 XXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
               P +CGP G C N  GS+ C+C +G+    +G
Sbjct: 878 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 912



 Score = 95.5 bits (227), Expect = 1e-19
 Identities = 64/214 (29%), Positives = 88/214 (41%), Gaps = 18/214 (8%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C DV+EC+     C    C N +GS+ C C    +  S  T    SR +     VD+
Sbjct: 954  GQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDL-DVDV 1012

Query: 62   RSGTETCRD-----------SDELSEDGTMAACCCSVGAAWGNYCD--PCPEPGSEAYRQ 108
                E  ++            + L+ + T   CCC+ GA WG+ C+  PCP  G+  + +
Sbjct: 1013 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE 1072

Query: 109  LCPGGPGYQPVLEPPSYV--VTLADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLA 165
            +CP G G+ P  E  S        D DEC    + +C +G C NT   + C C  G    
Sbjct: 1073 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 1132

Query: 166  PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
            P             P  C  G C N  GSY C C
Sbjct: 1133 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 1166



 Score = 93.9 bits (223), Expect = 4e-19
 Identities = 63/208 (30%), Positives = 90/208 (43%), Gaps = 21/208 (10%)

Query: 6   CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC   Q  C  G+C NT+GS+ C CP  +    +GT C D         VD    
Sbjct: 586 CVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCID---------VDECLR 636

Query: 65  TETCRDSDELSEDGTMAACCCSVG--AAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQ- 117
            + C +   ++  G      C  G        C   D C  P S    + C   PG YQ 
Sbjct: 637 PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNP-STCPDEQCVNSPGSYQC 695

Query: 118 -PVLEP-PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            P  E    +     D+DEC     +CA+G C+N  GS++C+C  G++  P         
Sbjct: 696 VPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDID 754

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
              + ++C  G C+N  GS+ C C +GY
Sbjct: 755 ECQQGNLCVNGQCKNTEGSFRCTCGQGY 782



 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 74/256 (28%), Positives = 104/256 (40%), Gaps = 42/256 (16%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS-G 64
            C D+DEC+ P SC  GQC+NT+GSY C C   + +V D +     R A    +++     
Sbjct: 1138 CFDMDECQDPSSCIDGQCVNTEGSYNCFC--THPMVLDASEKRCIRPAESNEQIEETDVY 1195

Query: 65   TETCRD--SDE-------LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC----- 110
             + C +  SDE       + +  T   CCC  G AWG  C  CP   S+ Y QLC     
Sbjct: 1196 QDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVT 1255

Query: 111  ----PGG--------PGYQPVLEP----PSYVVTLADI--DECAAHEGLCAHGTCTNTFG 152
                P G          Y P  +P      ++ +  ++  +EC    G C +G C     
Sbjct: 1256 GRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CENGRCVRVQE 1314

Query: 153  SFVCTCGAGWSLAPXXXX----XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
             + C C  G+ L                  R  +C    C N  GSY CLC  GYV  P+
Sbjct: 1315 GYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV--PS 1372

Query: 209  GSQYLLQNLSTNMRLK 224
                    L+T + L+
Sbjct: 1373 DKPNYCTPLNTALNLE 1388



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 44/117 (37%), Positives = 58/117 (49%), Gaps = 12/117 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCP------PNYELVSDGTACYDSRKARCYGKV 59
           C D++EC+    C  G+C+NT GSY C C       P +             K  CY  V
Sbjct: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLV 357

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
              SG +       LS   T   CCCSVG A G +C+ CP PG+ A++++CPGG GY
Sbjct: 358 S--SGRQCMHP---LSVHLTKQLCCCSVGKA-GPHCEKCPLPGTAAFKEICPGGMGY 408



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 60/208 (28%), Positives = 84/208 (40%), Gaps = 22/208 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C D+DEC+    C +GQC NT+GS+ C C   Y     G  C D  +  C          
Sbjct: 791 CEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE--CL------EDK 842

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNY--C---DPCPEPGSEAYRQLCPGGPGYQPVL 120
             C+  D ++  G+   C C  G    +   C   + C  PG    +  C    G    +
Sbjct: 843 SVCQRGDCINTAGSYD-CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCV 901

Query: 121 EPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               + +     T  DIDEC  +    +HG C NT GSF C C  G+  AP         
Sbjct: 902 CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ-APQDGQGCVDV 960

Query: 176 XXXR--PDVCGPGVCRNLPGSYVCLCPE 201
                   VCG   C N+ GS++C+C +
Sbjct: 961 NECELLSGVCGEAFCENVEGSFLCVCAD 988



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 52/169 (30%), Positives = 70/169 (41%), Gaps = 24/169 (14%)

Query: 3   GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C D++EC   +S CQ G CINT GSY C CP  ++L  D   C D  +    G    
Sbjct: 829 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPGLCGP 887

Query: 62  RS---GTE-----TCRDSDELSEDGTMAACCCSVGAAWGN-YCDP---CPEPGSEAYRQL 109
           +     TE      C+    +S DG     C  +     N  CD    C      ++R L
Sbjct: 888 QGECLNTEGSFHCVCQQGFSISADGRT---CEDIDECVNNTVCDSHGFCDNTAG-SFRCL 943

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTC 158
           C  G       + P       D++EC    G+C    C N  GSF+C C
Sbjct: 944 CYQG------FQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 986



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 8/86 (9%)

Query: 83  CCCSVGAAWG-NYCDPCPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
           CC +VG +WG N C  CP+ P    Y Q+    PGY+ V           DI+EC   +G
Sbjct: 255 CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN-----TFCQDINECQL-QG 308

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAP 166
           +C +G C NT GS+ CTC  G+   P
Sbjct: 309 VCPNGECLNTMGSYRCTCKIGFGPDP 334



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 129 LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD-VCGPGV 187
           + +I+EC  +  +C  G C N    + C C  G+  +             +   +C  G 
Sbjct: 544 VTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR 603

Query: 188 CRNLPGSYVCLCPEGYVAMPNGS 210
           C N  GS++C+CP G++A   G+
Sbjct: 604 CENTEGSFLCICPAGFMASEEGT 626



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 7/96 (7%)

Query: 4    FNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            F     +EC     C+ G+C+  Q  YTC C   Y L +    C D  +       +L +
Sbjct: 1290 FEELQAEECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECD-----ELNN 1344

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDP 97
                C+++  ++ DG+    C    V +   NYC P
Sbjct: 1345 RMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTP 1380


>AC019127-1|AAY24260.1|  697|Homo sapiens unknown protein.
          Length = 697

 Score =  107 bits (256), Expect = 4e-23
 Identities = 71/213 (33%), Positives = 87/213 (40%), Gaps = 22/213 (10%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC DVDEC  P  C  G C+NT G++ C  C   Y +   G  C D         +D 
Sbjct: 79  GTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG-RCED---------IDE 128

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVG-AAWGNYC---DPCPEPGSEAYRQLCPGGPGYQ 117
                TC D   ++  G+     C+ G   W   C   D C EP   A    C    G  
Sbjct: 129 CLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSY 187

Query: 118 PVLEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  Y  T       DIDEC     LC +G C NT GSF CTCG G+ L+       
Sbjct: 188 MCSCHKGYTRTPDHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCE 246

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                    +C  G CRN  GS+ C+C +GY A
Sbjct: 247 DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRA 279



 Score = 97.1 bits (231), Expect = 5e-20
 Identities = 67/217 (30%), Positives = 92/217 (42%), Gaps = 23/217 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           +C D+DEC+    C  GQC NT+GS+ C C   Y+L +    C D         +D    
Sbjct: 203 HCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED---------IDECQH 253

Query: 65  TETCRDSDELSEDGTMAACCCSVG---AAWGNYCD---PCPEPGSEAYRQLCPGGPGYQP 118
              C      + +G+   C C  G   +  G++C+    C E  S   R  C    G   
Sbjct: 254 RHLCAHGQCRNTEGSF-QCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD 312

Query: 119 VLEPPSYVV----TLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P  + +    T  DI+EC  H GLC   G C NT GSF C C  G+S++        
Sbjct: 313 CTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCED 371

Query: 174 XXXXXRPDVC-GPGVCRNLPGSYVCLCPEGYVAMPNG 209
                   VC   G C N  GS+ CLC +G+ A  +G
Sbjct: 372 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDG 408



 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 64/215 (29%), Positives = 85/215 (39%), Gaps = 22/215 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC  P  C  G C N +GSY C C   Y    D   C D         +D     
Sbjct: 163 CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRD---------IDECQQG 213

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP------GYQPV 119
             C +    + +G+   C C  G       D C +     +R LC  G        +Q V
Sbjct: 214 NLCVNGQCKNTEGSF-RCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCV 272

Query: 120 LEPPSYVVTLA----DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            +       L     DI+EC   + +C  G C NT GS+ CTC  G+ L           
Sbjct: 273 CDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDIN 331

Query: 176 XXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
               P +CGP G C N  GS+ C+C +G+    +G
Sbjct: 332 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 366



 Score = 93.9 bits (223), Expect = 4e-19
 Identities = 63/208 (30%), Positives = 90/208 (43%), Gaps = 21/208 (10%)

Query: 6   CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC   Q  C  G+C NT+GS+ C CP  +    +GT C D         VD    
Sbjct: 40  CVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCID---------VDECLR 90

Query: 65  TETCRDSDELSEDGTMAACCCSVG--AAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQ- 117
            + C +   ++  G      C  G        C   D C  P S    + C   PG YQ 
Sbjct: 91  PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNP-STCPDEQCVNSPGSYQC 149

Query: 118 -PVLEP-PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            P  E    +     D+DEC     +CA+G C+N  GS++C+C  G++  P         
Sbjct: 150 VPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDID 208

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
              + ++C  G C+N  GS+ C C +GY
Sbjct: 209 ECQQGNLCVNGQCKNTEGSFRCTCGQGY 236



 Score = 93.9 bits (223), Expect = 4e-19
 Identities = 63/214 (29%), Positives = 87/214 (40%), Gaps = 18/214 (8%)

Query: 3   GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C DV+EC+     C    C N +GS+ C C    +  S  T    SR +     VD+
Sbjct: 408 GQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDL-DVDV 466

Query: 62  RSGTETCRD-----------SDELSEDGTMAACCCSVGAAWGNYCD--PCPEPGSEAYRQ 108
               E  ++            + L+ + T   CCC+ G  WG+ C+  PCP  G+  + +
Sbjct: 467 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTE 526

Query: 109 LCPGGPGYQPVLEPPSYV--VTLADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLA 165
           +CP G G+ P  E  S        D DEC    + +C +G C NT   + C C  G    
Sbjct: 527 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 586

Query: 166 PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
           P             P  C  G C N  GSY C C
Sbjct: 587 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 620



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 60/208 (28%), Positives = 84/208 (40%), Gaps = 22/208 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C D+DEC+    C +GQC NT+GS+ C C   Y     G  C D  +  C          
Sbjct: 245 CEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE--CL------EDK 296

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNY--C---DPCPEPGSEAYRQLCPGGPGYQPVL 120
             C+  D ++  G+   C C  G    +   C   + C  PG    +  C    G    +
Sbjct: 297 SVCQRGDCINTAGSYD-CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCV 355

Query: 121 EPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               + +     T  DIDEC  +    +HG C NT GSF C C  G+  AP         
Sbjct: 356 CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ-APQDGQGCVDV 414

Query: 176 XXXR--PDVCGPGVCRNLPGSYVCLCPE 201
                   VCG   C N+ GS++C+C +
Sbjct: 415 NECELLSGVCGEAFCENVEGSFLCVCAD 442



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 52/169 (30%), Positives = 70/169 (41%), Gaps = 24/169 (14%)

Query: 3   GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C D++EC   +S CQ G CINT GSY C CP  ++L  D   C D  +    G    
Sbjct: 283 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPGLCGP 341

Query: 62  RS---GTE-----TCRDSDELSEDGTMAACCCSVGAAWGN-YCDP---CPEPGSEAYRQL 109
           +     TE      C+    +S DG     C  +     N  CD    C      ++R L
Sbjct: 342 QGECLNTEGSFHCVCQQGFSISADGRT---CEDIDECVNNTVCDSHGFCDNTAG-SFRCL 397

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTC 158
           C  G       + P       D++EC    G+C    C N  GSF+C C
Sbjct: 398 CYQG------FQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 440



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 37/104 (35%), Positives = 51/104 (49%), Gaps = 12/104 (11%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS-G 64
           C D+DEC+ P SC  GQC+NT+GSY C C   + +V D +     R A    +++     
Sbjct: 592 CFDMDECQDPSSCIDGQCVNTEGSYNCFC--THPMVLDASEKRCIRPAESNEQIEETDVY 649

Query: 65  TETCRD--SDE-------LSEDGTMAACCCSVGAAWGNYCDPCP 99
            + C +  SDE       + +  T   CCC  G AWG  C  CP
Sbjct: 650 QDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCP 693



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 1/80 (1%)

Query: 132 IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD-VCGPGVCRN 190
           I+EC  +  +C  G C N    + C C  G+  +             +   +C  G C N
Sbjct: 1   INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN 60

Query: 191 LPGSYVCLCPEGYVAMPNGS 210
             GS++C+CP G++A   G+
Sbjct: 61  TEGSFLCICPAGFMASEEGT 80


>AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming growth
           factor beta binding protein 1 isoform LTBP-1S varian
           protein.
          Length = 1348

 Score =  107 bits (256), Expect = 4e-23
 Identities = 71/213 (33%), Positives = 87/213 (40%), Gaps = 22/213 (10%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC DVDEC  P  C  G C+NT G++ C  C   Y +   G  C D         +D 
Sbjct: 579 GTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG-RCED---------IDE 628

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVG-AAWGNYC---DPCPEPGSEAYRQLCPGGPGYQ 117
                TC D   ++  G+     C+ G   W   C   D C EP   A    C    G  
Sbjct: 629 CLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSY 687

Query: 118 PVLEPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  Y  T       DIDEC     LC +G C NT GSF CTCG G+ L+       
Sbjct: 688 MCSCHKGYTRTPDHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCE 746

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
                    +C  G CRN  GS+ C+C +GY A
Sbjct: 747 DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRA 779



 Score = 97.1 bits (231), Expect = 5e-20
 Identities = 67/217 (30%), Positives = 92/217 (42%), Gaps = 23/217 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           +C D+DEC+    C  GQC NT+GS+ C C   Y+L +    C D         +D    
Sbjct: 703 HCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED---------IDECQH 753

Query: 65  TETCRDSDELSEDGTMAACCCSVG---AAWGNYCD---PCPEPGSEAYRQLCPGGPGYQP 118
              C      + +G+   C C  G   +  G++C+    C E  S   R  C    G   
Sbjct: 754 RHLCAHGQCRNTEGSF-QCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD 812

Query: 119 VLEPPSYVV----TLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P  + +    T  DI+EC  H GLC   G C NT GSF C C  G+S++        
Sbjct: 813 CTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCED 871

Query: 174 XXXXXRPDVC-GPGVCRNLPGSYVCLCPEGYVAMPNG 209
                   VC   G C N  GS+ CLC +G+ A  +G
Sbjct: 872 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDG 908



 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 64/215 (29%), Positives = 85/215 (39%), Gaps = 22/215 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C DVDEC  P  C  G C N +GSY C C   Y    D   C D         +D     
Sbjct: 663 CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRD---------IDECQQG 713

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP------GYQPV 119
             C +    + +G+   C C  G       D C +     +R LC  G        +Q V
Sbjct: 714 NLCVNGQCKNTEGSF-RCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCV 772

Query: 120 LEPPSYVVTLA----DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            +       L     DI+EC   + +C  G C NT GS+ CTC  G+ L           
Sbjct: 773 CDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDIN 831

Query: 176 XXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
               P +CGP G C N  GS+ C+C +G+    +G
Sbjct: 832 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 866



 Score = 95.5 bits (227), Expect = 1e-19
 Identities = 64/214 (29%), Positives = 88/214 (41%), Gaps = 18/214 (8%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C DV+EC+     C    C N +GS+ C C    +  S  T    SR +     VD+
Sbjct: 908  GQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDL-DVDV 966

Query: 62   RSGTETCRD-----------SDELSEDGTMAACCCSVGAAWGNYCD--PCPEPGSEAYRQ 108
                E  ++            + L+ + T   CCC+ GA WG+ C+  PCP  G+  + +
Sbjct: 967  DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE 1026

Query: 109  LCPGGPGYQPVLEPPSYV--VTLADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLA 165
            +CP G G+ P  E  S        D DEC    + +C +G C NT   + C C  G    
Sbjct: 1027 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 1086

Query: 166  PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
            P             P  C  G C N  GSY C C
Sbjct: 1087 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 1120



 Score = 93.9 bits (223), Expect = 4e-19
 Identities = 63/208 (30%), Positives = 90/208 (43%), Gaps = 21/208 (10%)

Query: 6   CTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C D+DEC   Q  C  G+C NT+GS+ C CP  +    +GT C D         VD    
Sbjct: 540 CVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCID---------VDECLR 590

Query: 65  TETCRDSDELSEDGTMAACCCSVG--AAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQ- 117
            + C +   ++  G      C  G        C   D C  P S    + C   PG YQ 
Sbjct: 591 PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNP-STCPDEQCVNSPGSYQC 649

Query: 118 -PVLEP-PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            P  E    +     D+DEC     +CA+G C+N  GS++C+C  G++  P         
Sbjct: 650 VPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDID 708

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
              + ++C  G C+N  GS+ C C +GY
Sbjct: 709 ECQQGNLCVNGQCKNTEGSFRCTCGQGY 736



 Score = 89.0 bits (211), Expect = 1e-17
 Identities = 74/256 (28%), Positives = 104/256 (40%), Gaps = 42/256 (16%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS-G 64
            C D+DEC+ P SC  GQC+NT+GSY C C   + +V D +     R A    +++     
Sbjct: 1092 CFDMDECQDPSSCIDGQCVNTEGSYNCFC--THPMVLDASEKRCIRPAESNEQIEETDVY 1149

Query: 65   TETCRD--SDE-------LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC----- 110
             + C +  SDE       + +  T   CCC  G AWG  C  CP   S+ Y QLC     
Sbjct: 1150 QDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVT 1209

Query: 111  ----PGG--------PGYQPVLEP----PSYVVTLADI--DECAAHEGLCAHGTCTNTFG 152
                P G          Y P  +P      ++ +  ++  +EC    G C +G C     
Sbjct: 1210 GRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CENGRCVRVQE 1268

Query: 153  SFVCTCGAGWSLAPXXXX----XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
             + C C  G+ L                  R  +C    C N  GSY CLC  GYV  P+
Sbjct: 1269 GYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV--PS 1326

Query: 209  GSQYLLQNLSTNMRLK 224
                    L+T + L+
Sbjct: 1327 DKPNYCTPLNTALNLE 1342



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 60/208 (28%), Positives = 84/208 (40%), Gaps = 22/208 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C D+DEC+    C +GQC NT+GS+ C C   Y     G  C D  +  C          
Sbjct: 745 CEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE--CL------EDK 796

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNY--C---DPCPEPGSEAYRQLCPGGPGYQPVL 120
             C+  D ++  G+   C C  G    +   C   + C  PG    +  C    G    +
Sbjct: 797 SVCQRGDCINTAGSYD-CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCV 855

Query: 121 EPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               + +     T  DIDEC  +    +HG C NT GSF C C  G+  AP         
Sbjct: 856 CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ-APQDGQGCVDV 914

Query: 176 XXXR--PDVCGPGVCRNLPGSYVCLCPE 201
                   VCG   C N+ GS++C+C +
Sbjct: 915 NECELLSGVCGEAFCENVEGSFLCVCAD 942



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 38/104 (36%), Positives = 48/104 (46%), Gaps = 11/104 (10%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCP------PNYELVSDGTACYDSRKARCYGKV 59
           C D++EC+    C  G+C+NT GSY C C       P +             K  CY  V
Sbjct: 304 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLV 363

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS 103
              SG +       LS   T   CCCSVG AWG +C+ CP PG+
Sbjct: 364 S--SGRQCMHP---LSVHLTKQLCCCSVGKAWGPHCEKCPLPGT 402



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 52/169 (30%), Positives = 70/169 (41%), Gaps = 24/169 (14%)

Query: 3   GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C D++EC   +S CQ G CINT GSY C CP  ++L  D   C D  +    G    
Sbjct: 783 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPGLCGP 841

Query: 62  RS---GTE-----TCRDSDELSEDGTMAACCCSVGAAWGN-YCDP---CPEPGSEAYRQL 109
           +     TE      C+    +S DG     C  +     N  CD    C      ++R L
Sbjct: 842 QGECLNTEGSFHCVCQQGFSISADGRT---CEDIDECVNNTVCDSHGFCDNTAG-SFRCL 897

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTC 158
           C  G       + P       D++EC    G+C    C N  GSF+C C
Sbjct: 898 CYQG------FQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 940



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 8/86 (9%)

Query: 83  CCCSVGAAWG-NYCDPCPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
           CC +VG +WG N C  CP+ P    Y Q+    PGY+ V           DI+EC   +G
Sbjct: 261 CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN-----TFCQDINECQL-QG 314

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAP 166
           +C +G C NT GS+ CTC  G+   P
Sbjct: 315 VCPNGECLNTMGSYRCTCKIGFGPDP 340



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 129 LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD-VCGPGV 187
           + +I+EC  +  +C  G C N    + C C  G+  +             +   +C  G 
Sbjct: 498 VTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR 557

Query: 188 CRNLPGSYVCLCPEGYVAMPNGS 210
           C N  GS++C+CP G++A   G+
Sbjct: 558 CENTEGSFLCICPAGFMASEEGT 580



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 7/96 (7%)

Query: 4    FNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            F     +EC     C+ G+C+  Q  YTC C   Y L +    C D  +       +L +
Sbjct: 1244 FEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECD-----ELNN 1298

Query: 64   GTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDP 97
                C+++  ++ DG+    C    V +   NYC P
Sbjct: 1299 RMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTP 1334


>Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein.
          Length = 1821

 Score =  105 bits (252), Expect = 1e-22
 Identities = 67/216 (31%), Positives = 87/216 (40%), Gaps = 18/216 (8%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYDSRKAR----C-YGKV 59
            C DVDEC S  SC  G C+NT+GS+ C  C   Y +  DGTAC D  +      C  G  
Sbjct: 1049 CQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVC 1108

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
               +G+ +C+D D       +   C  V        D C +P S      C    G    
Sbjct: 1109 TNTAGSFSCKDCDGGYRPSPLGDSCEDV--------DECEDPQSSCLGGECKNTVGSYQC 1160

Query: 120  LEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            L P  + +       D++EC   E    HG C N+ GSF C C  G+  A          
Sbjct: 1161 LCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVD 1220

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
                 D C  G C N  GS+ CLC  G+   P   +
Sbjct: 1221 ECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGE 1256



 Score =  103 bits (247), Expect = 5e-22
 Identities = 66/215 (30%), Positives = 95/215 (44%), Gaps = 19/215 (8%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELV-----------SDGTACYDS 50
            G++C DV+EC+   + C    C N +GS+ C C  + E             + G +  ++
Sbjct: 1340 GWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEA 1399

Query: 51   RK---ARCYGKVDLRSGTETCRD-SDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAY 106
                 A    ++D  SG +     S  L  + T A CCC+ GA WG+ CD CP   S  +
Sbjct: 1400 PTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGATWGDACDLCPSEDSAEF 1459

Query: 107  RQLCPGGPGYQPVLEPPSYVVTL-ADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSL 164
             ++CP G GY PV    ++  T+  D DEC     GLC +G C NT   +VC C  G+  
Sbjct: 1460 SEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHY 1519

Query: 165  APXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                          +   C  G C N  GS+ C C
Sbjct: 1520 -DASHKKCEDHDECQDLACENGECVNTEGSFHCFC 1553



 Score =  101 bits (243), Expect = 2e-21
 Identities = 66/216 (30%), Positives = 93/216 (43%), Gaps = 18/216 (8%)

Query: 5    NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCYGKVD 60
            +C DV+EC +P  C +G+C N +GS+ C C   YE+ SD   C D    + +A C   + 
Sbjct: 1007 SCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLC 1066

Query: 61   LRS----GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP--CPEPGSEAYRQLCPGGP 114
            L +        C +   ++EDGT  AC      A+   C    C         + C G  
Sbjct: 1067 LNTEGSFACSACENGYWVNEDGT--ACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDG-- 1122

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
            GY+P   P     +  D+DEC   +  C  G C NT GS+ C C  G+ LA         
Sbjct: 1123 GYRP--SPLG--DSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVN 1178

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
                       G C N  GS+ CLC  G+V+   G+
Sbjct: 1179 ECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGT 1214



 Score = 96.7 bits (230), Expect = 6e-20
 Identities = 45/114 (39%), Positives = 65/114 (57%), Gaps = 4/114 (3%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS- 63
           +C D++EC +   C+  +C+NT+GSY C C P   L    + C   +       +  RS 
Sbjct: 619 HCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSL 678

Query: 64  GTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
           G  TC  +  L++  T   CCCS VG AWG+ C+ CP PG+EA+R++CP G GY
Sbjct: 679 GPGTC--TLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHGY 730



 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 67/213 (31%), Positives = 99/213 (46%), Gaps = 27/213 (12%)

Query: 3    GFNCTDVDECKSPQSCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C DV+EC   + C  +G+C+N+ GS+ C C P +     GT+C D         VD 
Sbjct: 1171 GTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQD---------VDE 1221

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQL-CPGGP 114
             + T+ C     ++ +G+   C C  G   +     C   D C + G        C   P
Sbjct: 1222 CATTDPCVGGHCVNTEGSFN-CLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSP 1280

Query: 115  G-YQPVL--EPPSYVVT---LADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPX 167
            G Y+ VL  +P  ++       DIDECA ++ +C +HG C NT GSF C C  G+ ++P 
Sbjct: 1281 GSYRCVLGCQPGFHMAPNGDCIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEISPS 1339

Query: 168  X-XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                           VCG  +C N+ GS++CLC
Sbjct: 1340 GWDCVDVNECELMLAVCGAALCENVEGSFLCLC 1372



 Score = 95.1 bits (226), Expect = 2e-19
 Identities = 71/215 (33%), Positives = 89/215 (41%), Gaps = 23/215 (10%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D++EC+ P  C  GQC NT+GSY C C   Y +V  G  C D  + R  G        
Sbjct: 928  CQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINECRHPG-------- 978

Query: 66   ETCRDSDELSEDGTMAACCCSVG--AAWGNYCD--PCPEPGSEAYRQLCPGGPGYQPVLE 121
             TC D   ++  G+     C  G     G+  D   C  PG  A+ + C    G      
Sbjct: 979  -TCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGK-CTNLEGSFRCSC 1036

Query: 122  PPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCT-CGAGWSLAPXXXXXXXXX 175
               Y VT       D+DECA+    C  G C NT GSF C+ C  G+ +           
Sbjct: 1037 EQGYEVTSDEKGCQDVDECASRAS-CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLD 1095

Query: 176  XXXRPDVCGPGVCRNLPGSYVCL-CPEGYVAMPNG 209
                P VC  GVC N  GS+ C  C  GY   P G
Sbjct: 1096 ECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLG 1130



 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 72/226 (31%), Positives = 96/226 (42%), Gaps = 34/226 (15%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C DVDEC+ PQS C  G+C NT GSY C CP  ++L ++GT C D  +  C G+   
Sbjct: 1130 GDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNE--CMGE--- 1183

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG-------- 113
                E C    E         C C+ G         C +    A    C GG        
Sbjct: 1184 ----EHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGS 1239

Query: 114  ------PGYQPVLEPPSYVVTLADIDECAAH-EGLCAHGTCTNTFGSFVCT--CGAGWSL 164
                   G+QP  E    V    DIDEC  + + +C    C N+ GS+ C   C  G+ +
Sbjct: 1240 FNCLCETGFQPSPESGECV----DIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHM 1295

Query: 165  APXXXXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
            AP               +CG  G C N  GS+ CLC +G+   P+G
Sbjct: 1296 APNGDCIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEISPSG 1340



 Score = 87.0 bits (206), Expect = 5e-17
 Identities = 66/220 (30%), Positives = 91/220 (41%), Gaps = 28/220 (12%)

Query: 5    NCTDVDECKSPQSCQYGQCINTQGSYTC-RCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D++EC+ P +C  G+C+N+ GSYTC  C   Y       +C D  +    G      
Sbjct: 967  HCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLTPG------ 1018

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ------ 117
                C      + +G+   C C  G    +    C +    A R  CP G          
Sbjct: 1019 ---VCAHGKCTNLEGSF-RCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFA 1074

Query: 118  -PVLEPPSYV----VTLADIDECAAHEGLCAHGTCTNTFGSFVC-TCGAGWSLAPXXXXX 171
                E   +V        D+DEC A  G+C  G CTNT GSF C  C  G+  +P     
Sbjct: 1075 CSACENGYWVNEDGTACEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSC 1133

Query: 172  XXXXXXXRP-DVCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
                    P   C  G C+N  GSY CLCP+G+  + NG+
Sbjct: 1134 EDVDECEDPQSSCLGGECKNTVGSYQCLCPQGF-QLANGT 1172



 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 70/221 (31%), Positives = 91/221 (41%), Gaps = 23/221 (10%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYD-----SRKARCY 56
            G  C D+DEC  P  C  G C NT GS++C+ C   Y     G +C D       ++ C 
Sbjct: 1088 GTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCL 1147

Query: 57   G---KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWG-NYCDPCPEPGSEAYRQLCPG 112
            G   K  + S    C    +L+ +GT+   C  V    G  +C P  E  +      C  
Sbjct: 1148 GGECKNTVGSYQCLCPQGFQLA-NGTV---CEDVNECMGEEHCAPHGECLNSHGSFFCLC 1203

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX--X 170
             PG+       S      D+DECA  +  C  G C NT GSF C C  G+  +P      
Sbjct: 1204 APGFVSAEGGTS----CQDVDECATTDP-CVGGHCVNTEGSFNCLCETGFQPSPESGECV 1258

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCL--CPEGYVAMPNG 209
                       VCG   C N PGSY C+  C  G+   PNG
Sbjct: 1259 DIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG 1299



 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 63/217 (29%), Positives = 86/217 (39%), Gaps = 24/217 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTA--CYDSRKARCYGKVDLRS 63
            CTD +EC        G+CIN  GSY+C C P Y L + G    C D  +    G      
Sbjct: 885  CTDDNECLRDPCQGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPG------ 938

Query: 64   GTETCRDSDELSEDGTMAACCCSVG--AAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQ 117
                C      + +G+   C C  G       +C   + C  PG+      C   PG Y 
Sbjct: 939  ---VCSGGQCTNTEGSY-HCECDQGYIMVRKGHCQDINECRHPGT-CPDGRCVNSPGSYT 993

Query: 118  PVLEPPSY---VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
             +     Y     +  D++EC    G+CAHG CTN  GSF C+C  G+ +          
Sbjct: 994  CLACEEGYRGQSGSCVDVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDV 1052

Query: 175  XXXXRPDVCGPGVCRNLPGSYVC-LCPEGYVAMPNGS 210
                    C  G+C N  GS+ C  C  GY    +G+
Sbjct: 1053 DECASRASCPTGLCLNTEGSFACSACENGYWVNEDGT 1089



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/112 (31%), Positives = 47/112 (41%), Gaps = 8/112 (7%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-------CYGK 58
            C D DEC+   +C+ G+C+NT+GS+ C C P   L      C +S  +         +  
Sbjct: 1526 CEDHDECQD-LACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMD 1584

Query: 59   VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC 110
            +  +  T             T   CCC  G AW   C  CP   SE Y QLC
Sbjct: 1585 ICWKKVTNDVCSEPLRGHRTTYTECCCQDGKAWSQQCALCPPRSSEVYAQLC 1636



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 56/224 (25%), Positives = 79/224 (35%), Gaps = 25/224 (11%)

Query: 2    PGFNCTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-----ARC 55
            P  +C D+DEC +   C  +G C NT GS+ C C   +E+   G  C D  +     A C
Sbjct: 1297 PNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVC 1356

Query: 56   YGKV-DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGG 113
               + +   G+  C  + +L E       C   GA   +  + P  +      R  C  G
Sbjct: 1357 GAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSG 1416

Query: 114  P-GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCT------NTFGSFVCTCGAG----- 161
              G+ P         T A   EC   +G      C       +   S +C  G G     
Sbjct: 1417 QKGHAPCSSVLGRNTTQA---ECCCTQGATWGDACDLCPSEDSAEFSEICPSGKGYIPVE 1473

Query: 162  --WSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
              W+                P +C  G C N    YVCLC  G+
Sbjct: 1474 GAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGF 1517



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 41/101 (40%), Positives = 49/101 (48%), Gaps = 13/101 (12%)

Query: 71  SDELSEDGTMAACCCSVGAAWG-NYCDPCP-EPGSEAYR--QL-CPGGPGYQPVLEPPSY 125
           ++ L E  T   CC SVGA WG   C PCP  P S      QL CP   GY+ +      
Sbjct: 564 ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECP--QGYKRL-----N 616

Query: 126 VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
           +    DI+EC    GLC    C NT GS++CTC  G  L P
Sbjct: 617 LTHCQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDP 656



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 126 VVTLAD--IDECAAHE-GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +VTL+   ID CAA    +C  GTC N    + C C  G+ L P            R   
Sbjct: 837 LVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPC 896

Query: 183 CGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQNLS 218
            G G C N  GSY C C  GY    +G+    Q+++
Sbjct: 897 QGKGRCINRVGSYSCFCYPGYTLATSGATQECQDIN 932



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 6/89 (6%)

Query: 121  EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX---X 177
            EPP+    L   +EC    G C +G C      + C C  G+ L                
Sbjct: 1724 EPPAGFEGL-QAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDL 1781

Query: 178  XRPDV-CGPGVCRNLPGSYVCLCPEGYVA 205
              P V C  G C N  GSY C C  GYVA
Sbjct: 1782 NGPAVLCVHGYCENTEGSYRCHCSPGYVA 1810



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 6    CTDVDECKSPQS----CQYGQCINTQGSYTCRCPPNY 38
            C DV+EC         C +G C NT+GSY C C P Y
Sbjct: 1772 CVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGY 1808



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 15/47 (31%), Positives = 23/47 (48%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
            GF     +EC     C+ G+C+  +  YTC C   ++L +   AC D
Sbjct: 1728 GFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVD 1774


>S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growth
            factor-beta-binding protein-2 protein.
          Length = 1821

 Score =  105 bits (252), Expect = 1e-22
 Identities = 67/216 (31%), Positives = 87/216 (40%), Gaps = 18/216 (8%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYDSRKAR----C-YGKV 59
            C DVDEC S  SC  G C+NT+GS+ C  C   Y +  DGTAC D  +      C  G  
Sbjct: 1049 CQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVC 1108

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
               +G+ +C+D D       +   C  V        D C +P S      C    G    
Sbjct: 1109 TNTAGSFSCKDCDGGYRPSPLGDSCEDV--------DECEDPQSSCLGGECKNTVGSYQC 1160

Query: 120  LEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            L P  + +       D++EC   E    HG C N+ GSF C C  G+  A          
Sbjct: 1161 LCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVD 1220

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
                 D C  G C N  GS+ CLC  G+   P   +
Sbjct: 1221 ECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGE 1256



 Score =  103 bits (248), Expect = 4e-22
 Identities = 66/215 (30%), Positives = 96/215 (44%), Gaps = 19/215 (8%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELV-----------SDGTACYDS 50
            G++C DV+EC+   + C    C N +GS+ C C  + E             + G +  ++
Sbjct: 1340 GWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEA 1399

Query: 51   RK---ARCYGKVDLRSGTETCRD-SDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAY 106
                 A    ++D  SG +     S  L  + T A CCC+ GA+WG+ CD CP   S  +
Sbjct: 1400 PTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEF 1459

Query: 107  RQLCPGGPGYQPVLEPPSYVVTL-ADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSL 164
             ++CP G GY PV    ++  T+  D DEC     GLC +G C NT   +VC C  G+  
Sbjct: 1460 SEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHY 1519

Query: 165  APXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                          +   C  G C N  GS+ C C
Sbjct: 1520 -DASHKKCEDHDECQDLACENGECVNTEGSFHCFC 1553



 Score =  101 bits (243), Expect = 2e-21
 Identities = 66/216 (30%), Positives = 93/216 (43%), Gaps = 18/216 (8%)

Query: 5    NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCYGKVD 60
            +C DV+EC +P  C +G+C N +GS+ C C   YE+ SD   C D    + +A C   + 
Sbjct: 1007 SCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLC 1066

Query: 61   LRS----GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP--CPEPGSEAYRQLCPGGP 114
            L +        C +   ++EDGT  AC      A+   C    C         + C G  
Sbjct: 1067 LNTEGSFACSACENGYWVNEDGT--ACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDG-- 1122

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
            GY+P   P     +  D+DEC   +  C  G C NT GS+ C C  G+ LA         
Sbjct: 1123 GYRP--SPLG--DSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVN 1178

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
                       G C N  GS+ CLC  G+V+   G+
Sbjct: 1179 ECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGT 1214



 Score = 96.7 bits (230), Expect = 6e-20
 Identities = 45/114 (39%), Positives = 65/114 (57%), Gaps = 4/114 (3%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS- 63
           +C D++EC +   C+  +C+NT+GSY C C P   L    + C   +       +  RS 
Sbjct: 619 HCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSL 678

Query: 64  GTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
           G  TC  +  L++  T   CCCS VG AWG+ C+ CP PG+EA+R++CP G GY
Sbjct: 679 GPGTC--TLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHGY 730



 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 67/213 (31%), Positives = 99/213 (46%), Gaps = 27/213 (12%)

Query: 3    GFNCTDVDECKSPQSCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C DV+EC   + C  +G+C+N+ GS+ C C P +     GT+C D         VD 
Sbjct: 1171 GTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQD---------VDE 1221

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQL-CPGGP 114
             + T+ C     ++ +G+   C C  G   +     C   D C + G        C   P
Sbjct: 1222 CATTDPCVGGHCVNTEGSFN-CLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSP 1280

Query: 115  G-YQPVL--EPPSYVVT---LADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPX 167
            G Y+ VL  +P  ++       DIDECA ++ +C +HG C NT GSF C C  G+ ++P 
Sbjct: 1281 GSYRCVLGCQPGFHMAPNGDCIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEISPS 1339

Query: 168  X-XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                           VCG  +C N+ GS++CLC
Sbjct: 1340 GWDCVDVNECELMLAVCGAALCENVEGSFLCLC 1372



 Score = 95.1 bits (226), Expect = 2e-19
 Identities = 71/215 (33%), Positives = 89/215 (41%), Gaps = 23/215 (10%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D++EC+ P  C  GQC NT+GSY C C   Y +V  G  C D  + R  G        
Sbjct: 928  CQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINECRHPG-------- 978

Query: 66   ETCRDSDELSEDGTMAACCCSVG--AAWGNYCD--PCPEPGSEAYRQLCPGGPGYQPVLE 121
             TC D   ++  G+     C  G     G+  D   C  PG  A+ + C    G      
Sbjct: 979  -TCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGK-CTNLEGSFRCSC 1036

Query: 122  PPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCT-CGAGWSLAPXXXXXXXXX 175
               Y VT       D+DECA+    C  G C NT GSF C+ C  G+ +           
Sbjct: 1037 EQGYEVTSDEKGCQDVDECASRAS-CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLD 1095

Query: 176  XXXRPDVCGPGVCRNLPGSYVCL-CPEGYVAMPNG 209
                P VC  GVC N  GS+ C  C  GY   P G
Sbjct: 1096 ECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLG 1130



 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 72/226 (31%), Positives = 96/226 (42%), Gaps = 34/226 (15%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C DVDEC+ PQS C  G+C NT GSY C CP  ++L ++GT C D  +  C G+   
Sbjct: 1130 GDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNE--CMGE--- 1183

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG-------- 113
                E C    E         C C+ G         C +    A    C GG        
Sbjct: 1184 ----EHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGS 1239

Query: 114  ------PGYQPVLEPPSYVVTLADIDECAAH-EGLCAHGTCTNTFGSFVCT--CGAGWSL 164
                   G+QP  E    V    DIDEC  + + +C    C N+ GS+ C   C  G+ +
Sbjct: 1240 FNCLCETGFQPSPESGECV----DIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHM 1295

Query: 165  APXXXXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
            AP               +CG  G C N  GS+ CLC +G+   P+G
Sbjct: 1296 APNGDCIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEISPSG 1340



 Score = 87.0 bits (206), Expect = 5e-17
 Identities = 66/220 (30%), Positives = 91/220 (41%), Gaps = 28/220 (12%)

Query: 5    NCTDVDECKSPQSCQYGQCINTQGSYTC-RCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D++EC+ P +C  G+C+N+ GSYTC  C   Y       +C D  +    G      
Sbjct: 967  HCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLTPG------ 1018

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ------ 117
                C      + +G+   C C  G    +    C +    A R  CP G          
Sbjct: 1019 ---VCAHGKCTNLEGSF-RCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFA 1074

Query: 118  -PVLEPPSYV----VTLADIDECAAHEGLCAHGTCTNTFGSFVC-TCGAGWSLAPXXXXX 171
                E   +V        D+DEC A  G+C  G CTNT GSF C  C  G+  +P     
Sbjct: 1075 CSACENGYWVNEDGTACEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSC 1133

Query: 172  XXXXXXXRP-DVCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
                    P   C  G C+N  GSY CLCP+G+  + NG+
Sbjct: 1134 EDVDECEDPQSSCLGGECKNTVGSYQCLCPQGF-QLANGT 1172



 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 70/221 (31%), Positives = 91/221 (41%), Gaps = 23/221 (10%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYD-----SRKARCY 56
            G  C D+DEC  P  C  G C NT GS++C+ C   Y     G +C D       ++ C 
Sbjct: 1088 GTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCL 1147

Query: 57   G---KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWG-NYCDPCPEPGSEAYRQLCPG 112
            G   K  + S    C    +L+ +GT+   C  V    G  +C P  E  +      C  
Sbjct: 1148 GGECKNTVGSYQCLCPQGFQLA-NGTV---CEDVNECMGEEHCAPHGECLNSHGSFFCLC 1203

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX--X 170
             PG+       S      D+DECA  +  C  G C NT GSF C C  G+  +P      
Sbjct: 1204 APGFVSAEGGTS----CQDVDECATTDP-CVGGHCVNTEGSFNCLCETGFQPSPESGECV 1258

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCL--CPEGYVAMPNG 209
                       VCG   C N PGSY C+  C  G+   PNG
Sbjct: 1259 DIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG 1299



 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 63/217 (29%), Positives = 86/217 (39%), Gaps = 24/217 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTA--CYDSRKARCYGKVDLRS 63
            CTD +EC        G+CIN  GSY+C C P Y L + G    C D  +    G      
Sbjct: 885  CTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPG------ 938

Query: 64   GTETCRDSDELSEDGTMAACCCSVG--AAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQ 117
                C      + +G+   C C  G       +C   + C  PG+      C   PG Y 
Sbjct: 939  ---VCSGGQCTNTEGSY-HCECDQGYIMVRKGHCQDINECRHPGT-CPDGRCVNSPGSYT 993

Query: 118  PVLEPPSY---VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
             +     Y     +  D++EC    G+CAHG CTN  GSF C+C  G+ +          
Sbjct: 994  CLACEEGYRGQSGSCVDVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDV 1052

Query: 175  XXXXRPDVCGPGVCRNLPGSYVC-LCPEGYVAMPNGS 210
                    C  G+C N  GS+ C  C  GY    +G+
Sbjct: 1053 DECASRASCPTGLCLNTEGSFACSACENGYWVNEDGT 1089



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/112 (31%), Positives = 47/112 (41%), Gaps = 8/112 (7%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-------CYGK 58
            C D DEC+   +C+ G+C+NT+GS+ C C P   L      C +S  +         +  
Sbjct: 1526 CEDHDECQD-LACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMD 1584

Query: 59   VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC 110
            +  +  T             T   CCC  G AW   C  CP   SE Y QLC
Sbjct: 1585 ICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLC 1636



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 56/224 (25%), Positives = 79/224 (35%), Gaps = 25/224 (11%)

Query: 2    PGFNCTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-----ARC 55
            P  +C D+DEC +   C  +G C NT GS+ C C   +E+   G  C D  +     A C
Sbjct: 1297 PNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVC 1356

Query: 56   YGKV-DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGG 113
               + +   G+  C  + +L E       C   GA   +  + P  +      R  C  G
Sbjct: 1357 GAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSG 1416

Query: 114  P-GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCT------NTFGSFVCTCGAG----- 161
              G+ P         T A   EC   +G      C       +   S +C  G G     
Sbjct: 1417 QKGHAPCSSVLGRNTTQA---ECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVE 1473

Query: 162  --WSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
              W+                P +C  G C N    YVCLC  G+
Sbjct: 1474 GAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGF 1517



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 41/101 (40%), Positives = 49/101 (48%), Gaps = 13/101 (12%)

Query: 71  SDELSEDGTMAACCCSVGAAWG-NYCDPCP-EPGSEAYR--QL-CPGGPGYQPVLEPPSY 125
           ++ L E  T   CC SVGA WG   C PCP  P S      QL CP   GY+ +      
Sbjct: 564 ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECP--QGYKRL-----N 616

Query: 126 VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
           +    DI+EC    GLC    C NT GS++CTC  G  L P
Sbjct: 617 LTHCQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDP 656



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 126 VVTLAD--IDECAAHE-GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +VTL+   ID CAA    +C  GTC N    + C C  G+ L P            R   
Sbjct: 837 LVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPC 896

Query: 183 CGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQNLS 218
            G G C N  GSY C C  GY    +G+    Q+++
Sbjct: 897 KGKGRCINRVGSYSCFCYPGYTLATSGATQECQDIN 932



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 6/89 (6%)

Query: 121  EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX---X 177
            EPP+    L   +EC    G C +G C      + C C  G+ L                
Sbjct: 1724 EPPAGFEGL-QAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDL 1781

Query: 178  XRPDV-CGPGVCRNLPGSYVCLCPEGYVA 205
              P V C  G C N  GSY C C  GYVA
Sbjct: 1782 NGPAVLCVHGYCENTEGSYRCHCSPGYVA 1810



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 6    CTDVDECKSPQS----CQYGQCINTQGSYTCRCPPNY 38
            C DV+EC         C +G C NT+GSY C C P Y
Sbjct: 1772 CVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGY 1808



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 15/47 (31%), Positives = 23/47 (48%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
            GF     +EC     C+ G+C+  +  YTC C   ++L +   AC D
Sbjct: 1728 GFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVD 1774


>BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming growth
            factor beta binding protein 2 protein.
          Length = 1821

 Score =  105 bits (252), Expect = 1e-22
 Identities = 67/216 (31%), Positives = 87/216 (40%), Gaps = 18/216 (8%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYDSRKAR----C-YGKV 59
            C DVDEC S  SC  G C+NT+GS+ C  C   Y +  DGTAC D  +      C  G  
Sbjct: 1049 CQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVC 1108

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
               +G+ +C+D D       +   C  V        D C +P S      C    G    
Sbjct: 1109 TNTAGSFSCKDCDGGYRPSPLGDSCEDV--------DECEDPQSSCLGGECKNTVGSYQC 1160

Query: 120  LEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            L P  + +       D++EC   E    HG C N+ GSF C C  G+  A          
Sbjct: 1161 LCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVD 1220

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
                 D C  G C N  GS+ CLC  G+   P   +
Sbjct: 1221 ECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGE 1256



 Score =  103 bits (248), Expect = 4e-22
 Identities = 66/215 (30%), Positives = 96/215 (44%), Gaps = 19/215 (8%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELV-----------SDGTACYDS 50
            G++C DV+EC+   + C    C N +GS+ C C  + E             + G +  ++
Sbjct: 1340 GWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEA 1399

Query: 51   RK---ARCYGKVDLRSGTETCRD-SDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAY 106
                 A    ++D  SG +     S  L  + T A CCC+ GA+WG+ CD CP   S  +
Sbjct: 1400 PTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEF 1459

Query: 107  RQLCPGGPGYQPVLEPPSYVVTL-ADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSL 164
             ++CP G GY PV    ++  T+  D DEC     GLC +G C NT   +VC C  G+  
Sbjct: 1460 SEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHY 1519

Query: 165  APXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                          +   C  G C N  GS+ C C
Sbjct: 1520 -DASHKKCEDHDECQDLACENGECVNTEGSFHCFC 1553



 Score =  101 bits (243), Expect = 2e-21
 Identities = 66/216 (30%), Positives = 93/216 (43%), Gaps = 18/216 (8%)

Query: 5    NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCYGKVD 60
            +C DV+EC +P  C +G+C N +GS+ C C   YE+ SD   C D    + +A C   + 
Sbjct: 1007 SCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLC 1066

Query: 61   LRS----GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP--CPEPGSEAYRQLCPGGP 114
            L +        C +   ++EDGT  AC      A+   C    C         + C G  
Sbjct: 1067 LNTEGSFACSACENGYWVNEDGT--ACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDG-- 1122

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
            GY+P   P     +  D+DEC   +  C  G C NT GS+ C C  G+ LA         
Sbjct: 1123 GYRP--SPLG--DSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVN 1178

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
                       G C N  GS+ CLC  G+V+   G+
Sbjct: 1179 ECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGT 1214



 Score = 96.7 bits (230), Expect = 6e-20
 Identities = 45/114 (39%), Positives = 65/114 (57%), Gaps = 4/114 (3%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS- 63
           +C D++EC +   C+  +C+NT+GSY C C P   L    + C   +       +  RS 
Sbjct: 619 HCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSL 678

Query: 64  GTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
           G  TC  +  L++  T   CCCS VG AWG+ C+ CP PG+EA+R++CP G GY
Sbjct: 679 GPGTC--TLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHGY 730



 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 67/213 (31%), Positives = 99/213 (46%), Gaps = 27/213 (12%)

Query: 3    GFNCTDVDECKSPQSCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C DV+EC   + C  +G+C+N+ GS+ C C P +     GT+C D         VD 
Sbjct: 1171 GTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQD---------VDE 1221

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQL-CPGGP 114
             + T+ C     ++ +G+   C C  G   +     C   D C + G        C   P
Sbjct: 1222 CATTDPCVGGHCVNTEGSFN-CLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSP 1280

Query: 115  G-YQPVL--EPPSYVVT---LADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPX 167
            G Y+ VL  +P  ++       DIDECA ++ +C +HG C NT GSF C C  G+ ++P 
Sbjct: 1281 GSYRCVLGCQPGFHMAPNGDCIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEISPS 1339

Query: 168  X-XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                           VCG  +C N+ GS++CLC
Sbjct: 1340 GWDCVDVNECELMLAVCGAALCENVEGSFLCLC 1372



 Score = 95.1 bits (226), Expect = 2e-19
 Identities = 71/215 (33%), Positives = 89/215 (41%), Gaps = 23/215 (10%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D++EC+ P  C  GQC NT+GSY C C   Y +V  G  C D  + R  G        
Sbjct: 928  CQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINECRHPG-------- 978

Query: 66   ETCRDSDELSEDGTMAACCCSVG--AAWGNYCD--PCPEPGSEAYRQLCPGGPGYQPVLE 121
             TC D   ++  G+     C  G     G+  D   C  PG  A+ + C    G      
Sbjct: 979  -TCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGK-CTNLEGSFRCSC 1036

Query: 122  PPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCT-CGAGWSLAPXXXXXXXXX 175
               Y VT       D+DECA+    C  G C NT GSF C+ C  G+ +           
Sbjct: 1037 EQGYEVTSDEKGCQDVDECASRAS-CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLD 1095

Query: 176  XXXRPDVCGPGVCRNLPGSYVCL-CPEGYVAMPNG 209
                P VC  GVC N  GS+ C  C  GY   P G
Sbjct: 1096 ECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLG 1130



 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 72/226 (31%), Positives = 96/226 (42%), Gaps = 34/226 (15%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C DVDEC+ PQS C  G+C NT GSY C CP  ++L ++GT C D  +  C G+   
Sbjct: 1130 GDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNE--CMGE--- 1183

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG-------- 113
                E C    E         C C+ G         C +    A    C GG        
Sbjct: 1184 ----EHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGS 1239

Query: 114  ------PGYQPVLEPPSYVVTLADIDECAAH-EGLCAHGTCTNTFGSFVCT--CGAGWSL 164
                   G+QP  E    V    DIDEC  + + +C    C N+ GS+ C   C  G+ +
Sbjct: 1240 FNCLCETGFQPSPESGECV----DIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHM 1295

Query: 165  APXXXXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
            AP               +CG  G C N  GS+ CLC +G+   P+G
Sbjct: 1296 APNGDCIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEISPSG 1340



 Score = 87.0 bits (206), Expect = 5e-17
 Identities = 66/220 (30%), Positives = 91/220 (41%), Gaps = 28/220 (12%)

Query: 5    NCTDVDECKSPQSCQYGQCINTQGSYTC-RCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D++EC+ P +C  G+C+N+ GSYTC  C   Y       +C D  +    G      
Sbjct: 967  HCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLTPG------ 1018

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ------ 117
                C      + +G+   C C  G    +    C +    A R  CP G          
Sbjct: 1019 ---VCAHGKCTNLEGSF-RCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFA 1074

Query: 118  -PVLEPPSYV----VTLADIDECAAHEGLCAHGTCTNTFGSFVC-TCGAGWSLAPXXXXX 171
                E   +V        D+DEC A  G+C  G CTNT GSF C  C  G+  +P     
Sbjct: 1075 CSACENGYWVNEDGTACEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSC 1133

Query: 172  XXXXXXXRP-DVCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
                    P   C  G C+N  GSY CLCP+G+  + NG+
Sbjct: 1134 EDVDECEDPQSSCLGGECKNTVGSYQCLCPQGF-QLANGT 1172



 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 70/221 (31%), Positives = 91/221 (41%), Gaps = 23/221 (10%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYD-----SRKARCY 56
            G  C D+DEC  P  C  G C NT GS++C+ C   Y     G +C D       ++ C 
Sbjct: 1088 GTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCL 1147

Query: 57   G---KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWG-NYCDPCPEPGSEAYRQLCPG 112
            G   K  + S    C    +L+ +GT+   C  V    G  +C P  E  +      C  
Sbjct: 1148 GGECKNTVGSYQCLCPQGFQLA-NGTV---CEDVNECMGEEHCAPHGECLNSHGSFFCLC 1203

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX--X 170
             PG+       S      D+DECA  +  C  G C NT GSF C C  G+  +P      
Sbjct: 1204 APGFVSAEGGTS----CQDVDECATTDP-CVGGHCVNTEGSFNCLCETGFQPSPESGECV 1258

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCL--CPEGYVAMPNG 209
                       VCG   C N PGSY C+  C  G+   PNG
Sbjct: 1259 DIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG 1299



 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 63/217 (29%), Positives = 86/217 (39%), Gaps = 24/217 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTA--CYDSRKARCYGKVDLRS 63
            CTD +EC        G+CIN  GSY+C C P Y L + G    C D  +    G      
Sbjct: 885  CTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPG------ 938

Query: 64   GTETCRDSDELSEDGTMAACCCSVG--AAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQ 117
                C      + +G+   C C  G       +C   + C  PG+      C   PG Y 
Sbjct: 939  ---VCSGGQCTNTEGSY-HCECDQGYIMVRKGHCQDINECRHPGT-CPDGRCVNSPGSYT 993

Query: 118  PVLEPPSY---VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
             +     Y     +  D++EC    G+CAHG CTN  GSF C+C  G+ +          
Sbjct: 994  CLACEEGYRGQSGSCVDVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDV 1052

Query: 175  XXXXRPDVCGPGVCRNLPGSYVC-LCPEGYVAMPNGS 210
                    C  G+C N  GS+ C  C  GY    +G+
Sbjct: 1053 DECASRASCPTGLCLNTEGSFACSACENGYWVNEDGT 1089



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/112 (31%), Positives = 47/112 (41%), Gaps = 8/112 (7%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-------CYGK 58
            C D DEC+   +C+ G+C+NT+GS+ C C P   L      C +S  +         +  
Sbjct: 1526 CEDHDECQD-LACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMD 1584

Query: 59   VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC 110
            +  +  T             T   CCC  G AW   C  CP   SE Y QLC
Sbjct: 1585 ICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLC 1636



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 56/224 (25%), Positives = 79/224 (35%), Gaps = 25/224 (11%)

Query: 2    PGFNCTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-----ARC 55
            P  +C D+DEC +   C  +G C NT GS+ C C   +E+   G  C D  +     A C
Sbjct: 1297 PNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVC 1356

Query: 56   YGKV-DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGG 113
               + +   G+  C  + +L E       C   GA   +  + P  +      R  C  G
Sbjct: 1357 GAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSG 1416

Query: 114  P-GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCT------NTFGSFVCTCGAG----- 161
              G+ P         T A   EC   +G      C       +   S +C  G G     
Sbjct: 1417 QKGHAPCSSVLGRNTTQA---ECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVE 1473

Query: 162  --WSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
              W+                P +C  G C N    YVCLC  G+
Sbjct: 1474 GAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGF 1517



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 41/101 (40%), Positives = 49/101 (48%), Gaps = 13/101 (12%)

Query: 71  SDELSEDGTMAACCCSVGAAWG-NYCDPCP-EPGSEAYR--QL-CPGGPGYQPVLEPPSY 125
           ++ L E  T   CC SVGA WG   C PCP  P S      QL CP   GY+ +      
Sbjct: 564 ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECP--QGYKRL-----N 616

Query: 126 VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
           +    DI+EC    GLC    C NT GS++CTC  G  L P
Sbjct: 617 LTHCQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDP 656



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 126 VVTLAD--IDECAAHE-GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +VTL+   ID CAA    +C  GTC N    + C C  G+ L P            R   
Sbjct: 837 LVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPC 896

Query: 183 CGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQNLS 218
            G G C N  GSY C C  GY    +G+    Q+++
Sbjct: 897 KGKGRCINRVGSYSCFCYPGYTLATSGATQECQDIN 932



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 6/89 (6%)

Query: 121  EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX---X 177
            EPP+    L   +EC    G C +G C      + C C  G+ L                
Sbjct: 1724 EPPAGFEGL-QAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDL 1781

Query: 178  XRPDV-CGPGVCRNLPGSYVCLCPEGYVA 205
              P V C  G C N  GSY C C  GYVA
Sbjct: 1782 NGPAVLCVHGYCENTEGSYRCHCSPGYVA 1810



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 6    CTDVDECKSPQS----CQYGQCINTQGSYTCRCPPNY 38
            C DV+EC         C +G C NT+GSY C C P Y
Sbjct: 1772 CVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGY 1808



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 15/47 (31%), Positives = 23/47 (48%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
            GF     +EC     C+ G+C+  +  YTC C   ++L +   AC D
Sbjct: 1728 GFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVD 1774


>AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming growth
            factor beta binding protein 2 variant protein.
          Length = 1700

 Score =  105 bits (252), Expect = 1e-22
 Identities = 67/216 (31%), Positives = 87/216 (40%), Gaps = 18/216 (8%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYDSRKAR----C-YGKV 59
            C DVDEC S  SC  G C+NT+GS+ C  C   Y +  DGTAC D  +      C  G  
Sbjct: 928  CQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVC 987

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
               +G+ +C+D D       +   C  V        D C +P S      C    G    
Sbjct: 988  TNTAGSFSCKDCDGGYRPSPLGDSCEDV--------DECEDPQSSCLGGECKNTVGSYQC 1039

Query: 120  LEPPSYVVT----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
            L P  + +       D++EC   E    HG C N+ GSF C C  G+  A          
Sbjct: 1040 LCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVD 1099

Query: 176  XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
                 D C  G C N  GS+ CLC  G+   P   +
Sbjct: 1100 ECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGE 1135



 Score =  103 bits (248), Expect = 4e-22
 Identities = 66/215 (30%), Positives = 96/215 (44%), Gaps = 19/215 (8%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELV-----------SDGTACYDS 50
            G++C DV+EC+   + C    C N +GS+ C C  + E             + G +  ++
Sbjct: 1219 GWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEA 1278

Query: 51   RK---ARCYGKVDLRSGTETCRD-SDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAY 106
                 A    ++D  SG +     S  L  + T A CCC+ GA+WG+ CD CP   S  +
Sbjct: 1279 PTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEF 1338

Query: 107  RQLCPGGPGYQPVLEPPSYVVTL-ADIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSL 164
             ++CP G GY PV    ++  T+  D DEC     GLC +G C NT   +VC C  G+  
Sbjct: 1339 SEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHY 1398

Query: 165  APXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                          +   C  G C N  GS+ C C
Sbjct: 1399 -DASHKKCEDHDECQDLACENGECVNTEGSFHCFC 1432



 Score =  101 bits (243), Expect = 2e-21
 Identities = 66/216 (30%), Positives = 93/216 (43%), Gaps = 18/216 (8%)

Query: 5    NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD----SRKARCYGKVD 60
            +C DV+EC +P  C +G+C N +GS+ C C   YE+ SD   C D    + +A C   + 
Sbjct: 886  SCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLC 945

Query: 61   LRS----GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP--CPEPGSEAYRQLCPGGP 114
            L +        C +   ++EDGT  AC      A+   C    C         + C G  
Sbjct: 946  LNTEGSFACSACENGYWVNEDGT--ACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDG-- 1001

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
            GY+P   P     +  D+DEC   +  C  G C NT GS+ C C  G+ LA         
Sbjct: 1002 GYRP--SPLG--DSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVN 1057

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
                       G C N  GS+ CLC  G+V+   G+
Sbjct: 1058 ECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGT 1093



 Score = 96.7 bits (230), Expect = 6e-20
 Identities = 45/114 (39%), Positives = 65/114 (57%), Gaps = 4/114 (3%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS- 63
           +C D++EC +   C+  +C+NT+GSY C C P   L    + C   +       +  RS 
Sbjct: 498 HCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSL 557

Query: 64  GTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
           G  TC  +  L++  T   CCCS VG AWG+ C+ CP PG+EA+R++CP G GY
Sbjct: 558 GPGTC--TLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHGY 609



 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 67/213 (31%), Positives = 99/213 (46%), Gaps = 27/213 (12%)

Query: 3    GFNCTDVDECKSPQSCQ-YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C DV+EC   + C  +G+C+N+ GS+ C C P +     GT+C D         VD 
Sbjct: 1050 GTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQD---------VDE 1100

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQL-CPGGP 114
             + T+ C     ++ +G+   C C  G   +     C   D C + G        C   P
Sbjct: 1101 CATTDPCVGGHCVNTEGSFN-CLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSP 1159

Query: 115  G-YQPVL--EPPSYVVT---LADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPX 167
            G Y+ VL  +P  ++       DIDECA ++ +C +HG C NT GSF C C  G+ ++P 
Sbjct: 1160 GSYRCVLGCQPGFHMAPNGDCIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEISPS 1218

Query: 168  X-XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                           VCG  +C N+ GS++CLC
Sbjct: 1219 GWDCVDVNECELMLAVCGAALCENVEGSFLCLC 1251



 Score = 95.1 bits (226), Expect = 2e-19
 Identities = 71/215 (33%), Positives = 89/215 (41%), Gaps = 23/215 (10%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D++EC+ P  C  GQC NT+GSY C C   Y +V  G  C D  + R  G        
Sbjct: 807  CQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINECRHPG-------- 857

Query: 66   ETCRDSDELSEDGTMAACCCSVG--AAWGNYCD--PCPEPGSEAYRQLCPGGPGYQPVLE 121
             TC D   ++  G+     C  G     G+  D   C  PG  A+ + C    G      
Sbjct: 858  -TCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGK-CTNLEGSFRCSC 915

Query: 122  PPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCT-CGAGWSLAPXXXXXXXXX 175
               Y VT       D+DECA+    C  G C NT GSF C+ C  G+ +           
Sbjct: 916  EQGYEVTSDEKGCQDVDECASRAS-CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLD 974

Query: 176  XXXRPDVCGPGVCRNLPGSYVCL-CPEGYVAMPNG 209
                P VC  GVC N  GS+ C  C  GY   P G
Sbjct: 975  ECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLG 1009



 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 72/226 (31%), Positives = 96/226 (42%), Gaps = 34/226 (15%)

Query: 3    GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C DVDEC+ PQS C  G+C NT GSY C CP  ++L ++GT C D  +  C G+   
Sbjct: 1009 GDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNE--CMGE--- 1062

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG-------- 113
                E C    E         C C+ G         C +    A    C GG        
Sbjct: 1063 ----EHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGS 1118

Query: 114  ------PGYQPVLEPPSYVVTLADIDECAAH-EGLCAHGTCTNTFGSFVCT--CGAGWSL 164
                   G+QP  E    V    DIDEC  + + +C    C N+ GS+ C   C  G+ +
Sbjct: 1119 FNCLCETGFQPSPESGECV----DIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHM 1174

Query: 165  APXXXXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
            AP               +CG  G C N  GS+ CLC +G+   P+G
Sbjct: 1175 APNGDCIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEISPSG 1219



 Score = 87.0 bits (206), Expect = 5e-17
 Identities = 66/220 (30%), Positives = 91/220 (41%), Gaps = 28/220 (12%)

Query: 5    NCTDVDECKSPQSCQYGQCINTQGSYTC-RCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
            +C D++EC+ P +C  G+C+N+ GSYTC  C   Y       +C D  +    G      
Sbjct: 846  HCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLTPG------ 897

Query: 64   GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ------ 117
                C      + +G+   C C  G    +    C +    A R  CP G          
Sbjct: 898  ---VCAHGKCTNLEGSF-RCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFA 953

Query: 118  -PVLEPPSYV----VTLADIDECAAHEGLCAHGTCTNTFGSFVC-TCGAGWSLAPXXXXX 171
                E   +V        D+DEC A  G+C  G CTNT GSF C  C  G+  +P     
Sbjct: 954  CSACENGYWVNEDGTACEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSC 1012

Query: 172  XXXXXXXRP-DVCGPGVCRNLPGSYVCLCPEGYVAMPNGS 210
                    P   C  G C+N  GSY CLCP+G+  + NG+
Sbjct: 1013 EDVDECEDPQSSCLGGECKNTVGSYQCLCPQGF-QLANGT 1051



 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 70/221 (31%), Positives = 91/221 (41%), Gaps = 23/221 (10%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYELVSDGTACYD-----SRKARCY 56
            G  C D+DEC  P  C  G C NT GS++C+ C   Y     G +C D       ++ C 
Sbjct: 967  GTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCL 1026

Query: 57   G---KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWG-NYCDPCPEPGSEAYRQLCPG 112
            G   K  + S    C    +L+ +GT+   C  V    G  +C P  E  +      C  
Sbjct: 1027 GGECKNTVGSYQCLCPQGFQLA-NGTV---CEDVNECMGEEHCAPHGECLNSHGSFFCLC 1082

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX--X 170
             PG+       S      D+DECA  +  C  G C NT GSF C C  G+  +P      
Sbjct: 1083 APGFVSAEGGTS----CQDVDECATTDP-CVGGHCVNTEGSFNCLCETGFQPSPESGECV 1137

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCL--CPEGYVAMPNG 209
                       VCG   C N PGSY C+  C  G+   PNG
Sbjct: 1138 DIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG 1178



 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 63/217 (29%), Positives = 86/217 (39%), Gaps = 24/217 (11%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTA--CYDSRKARCYGKVDLRS 63
           CTD +EC        G+CIN  GSY+C C P Y L + G    C D  +    G      
Sbjct: 764 CTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPG------ 817

Query: 64  GTETCRDSDELSEDGTMAACCCSVG--AAWGNYC---DPCPEPGSEAYRQLCPGGPG-YQ 117
               C      + +G+   C C  G       +C   + C  PG+      C   PG Y 
Sbjct: 818 ---VCSGGQCTNTEGSY-HCECDQGYIMVRKGHCQDINECRHPGT-CPDGRCVNSPGSYT 872

Query: 118 PVLEPPSY---VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
            +     Y     +  D++EC    G+CAHG CTN  GSF C+C  G+ +          
Sbjct: 873 CLACEEGYRGQSGSCVDVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDV 931

Query: 175 XXXXRPDVCGPGVCRNLPGSYVC-LCPEGYVAMPNGS 210
                   C  G+C N  GS+ C  C  GY    +G+
Sbjct: 932 DECASRASCPTGLCLNTEGSFACSACENGYWVNEDGT 968



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 35/112 (31%), Positives = 47/112 (41%), Gaps = 8/112 (7%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-------CYGK 58
            C D DEC+   +C+ G+C+NT+GS+ C C P   L      C +S  +         +  
Sbjct: 1405 CEDHDECQD-LACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMD 1463

Query: 59   VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC 110
            +  +  T             T   CCC  G AW   C  CP   SE Y QLC
Sbjct: 1464 ICWKKATNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLC 1515



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 56/224 (25%), Positives = 79/224 (35%), Gaps = 25/224 (11%)

Query: 2    PGFNCTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK-----ARC 55
            P  +C D+DEC +   C  +G C NT GS+ C C   +E+   G  C D  +     A C
Sbjct: 1176 PNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVC 1235

Query: 56   YGKV-DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGG 113
               + +   G+  C  + +L E       C   GA   +  + P  +      R  C  G
Sbjct: 1236 GAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSG 1295

Query: 114  P-GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCT------NTFGSFVCTCGAG----- 161
              G+ P         T A   EC   +G      C       +   S +C  G G     
Sbjct: 1296 QKGHAPCSSVLGRNTTQA---ECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVE 1352

Query: 162  --WSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
              W+                P +C  G C N    YVCLC  G+
Sbjct: 1353 GAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGF 1396



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 41/101 (40%), Positives = 49/101 (48%), Gaps = 13/101 (12%)

Query: 71  SDELSEDGTMAACCCSVGAAWG-NYCDPCP-EPGSEAYR--QL-CPGGPGYQPVLEPPSY 125
           ++ L E  T   CC SVGA WG   C PCP  P S      QL CP   GY+ +      
Sbjct: 443 ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECP--QGYKRL-----N 495

Query: 126 VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
           +    DI+EC    GLC    C NT GS++CTC  G  L P
Sbjct: 496 LTHCQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDP 535



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 126 VVTLAD--IDECAAHE-GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +VTL+   ID CAA    +C  GTC N    + C C  G+ L P            R   
Sbjct: 716 LVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPC 775

Query: 183 CGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQNLS 218
            G G C N  GSY C C  GY    +G+    Q+++
Sbjct: 776 KGKGRCINRVGSYSCFCYPGYTLATSGATQECQDIN 811



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 6/89 (6%)

Query: 121  EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX---X 177
            EPP+    L   +EC    G C +G C      + C C  G+ L                
Sbjct: 1603 EPPAGFEGL-QAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDL 1660

Query: 178  XRPDV-CGPGVCRNLPGSYVCLCPEGYVA 205
              P V C  G C N  GSY C C  GYVA
Sbjct: 1661 NGPAVLCVHGYCENTEGSYRCHCSPGYVA 1689



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 6    CTDVDECKSPQS----CQYGQCINTQGSYTCRCPPNY 38
            C DV+EC         C +G C NT+GSY C C P Y
Sbjct: 1651 CVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGY 1687



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 15/47 (31%), Positives = 23/47 (48%)

Query: 3    GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
            GF     +EC     C+ G+C+  +  YTC C   ++L +   AC D
Sbjct: 1607 GFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVD 1653


>AF054502-1|AAC39882.1|  669|Homo sapiens latent transforming growth
           factor-beta binding protein 4 protein.
          Length = 669

 Score =   99 bits (238), Expect = 6e-21
 Identities = 71/220 (32%), Positives = 93/220 (42%), Gaps = 18/220 (8%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCR-CPPNYEL----VSDGTACYDSRKARC-- 55
           G  C DVDEC++  +C   +C+N+ GS+ CR CP  + L     +D   C  S    C  
Sbjct: 12  GSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDEC-SSGAPPCGP 70

Query: 56  YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAW-GNYCDPCPEPGSEAYRQLCPGGP 114
           +G      G+  C  +            C  V     G++C P  E  +      C   P
Sbjct: 71  HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAP 130

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
           GY+P     S +    D+DEC + E LC  G CTNT GSF C C  G    P        
Sbjct: 131 GYRPGPRGASCL----DVDEC-SEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDV 185

Query: 175 XXXXR--PDVCGPGVCRNLPGSYVCL--CPEGYVAMPNGS 210
                  P +CG   C N PGSY C+  C  GY A P G+
Sbjct: 186 DECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT 225



 Score = 89.8 bits (213), Expect = 7e-18
 Identities = 62/210 (29%), Positives = 85/210 (40%), Gaps = 23/210 (10%)

Query: 6   CTDVDECKS--PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           CTDVDEC S  P    +G C NT+GS+ C C P Y   S        R   C    +   
Sbjct: 55  CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS-------GRPGPCADVNECLE 107

Query: 64  GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG-----PGYQP 118
           G       + L+ DG+ A C C+ G   G     C +    +   LC  G      G   
Sbjct: 108 GDFCFPHGECLNTDGSFA-CTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE 166

Query: 119 VLEPPSY-----VVTLADIDECAAH-EGLCAHGTCTNTFGSFVCT--CGAGWSLAPXXXX 170
            + PP +     + +  D+DEC      LC    C N+ GS+ C   C  G+   P    
Sbjct: 167 CICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC 226

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
                      VCG  +C N+ GS++C+CP
Sbjct: 227 DDVNECETLQGVCGAALCENVEGSFLCVCP 256



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 46/142 (32%), Positives = 59/142 (41%), Gaps = 9/142 (6%)

Query: 74  LSEDGTMAACCCSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLAD 131
           L+ + T   CCC+VG  WG+ C    CP   +  Y+ LCP G GY   L P   +    D
Sbjct: 334 LARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGY---LAPSGDLSLRRD 390

Query: 132 IDECAA-HEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRPDVCGPGVCR 189
           +DEC    + +C  G C NT   + C C  G+                     C  G C 
Sbjct: 391 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 450

Query: 190 NLPGSYVCLCPEGYVAMPNGSQ 211
           N  GSY C C    V   +GSQ
Sbjct: 451 NTVGSYHCTCEPPLVL--DGSQ 470



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 43/128 (33%), Positives = 56/128 (43%), Gaps = 19/128 (14%)

Query: 6   CTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYEL-------VSDGTACYDSRKARCYG 57
           C D DEC   + +C+ G+C+NT GSY C C P   L       VS+ +   D     C+ 
Sbjct: 431 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 490

Query: 58  KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
           +V    G +       L    T   CCC  G AWG  C  CP   S+ +  LC       
Sbjct: 491 EV----GADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC------- 539

Query: 118 PVLEPPSY 125
            VL PP+Y
Sbjct: 540 NVLRPPAY 547



 Score = 59.7 bits (138), Expect = 8e-09
 Identities = 34/87 (39%), Positives = 41/87 (47%), Gaps = 5/87 (5%)

Query: 131 DIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGWSLAPXXXXX--XXXXXXXRPDVCGP-G 186
           D+DEC++    C  HG CTNT GSF C+C  G+  AP                D C P G
Sbjct: 57  DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR-APSGRPGPCADVNECLEGDFCFPHG 115

Query: 187 VCRNLPGSYVCLCPEGYVAMPNGSQYL 213
            C N  GS+ C C  GY   P G+  L
Sbjct: 116 ECLNTDGSFACTCAPGYRPGPRGASCL 142



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 8/84 (9%)

Query: 8   DVDECK--SPQSCQYGQCINTQGSYTCRCPPNYELVS------DGTACYDSRKARCYGKV 59
           DVDEC+    Q C+ G C+NT   Y+C C   Y   +      D   C D   A   G+ 
Sbjct: 390 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 449

Query: 60  DLRSGTETCRDSDELSEDGTMAAC 83
               G+  C     L  DG+   C
Sbjct: 450 VNTVGSYHCTCEPPLVLDGSQRRC 473



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 1/39 (2%)

Query: 2   PGFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYE 39
           P   C DV+EC++ Q  C    C N +GS+ C CP + E
Sbjct: 222 PEGTCDDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 260


>AC013451-1|AAF87081.1|  969|Homo sapiens LTBP-2 protein.
          Length = 969

 Score = 96.7 bits (230), Expect = 6e-20
 Identities = 45/114 (39%), Positives = 65/114 (57%), Gaps = 4/114 (3%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS- 63
           +C D++EC +   C+  +C+NT+GSY C C P   L    + C   +       +  RS 
Sbjct: 619 HCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSL 678

Query: 64  GTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
           G  TC  +  L++  T   CCCS VG AWG+ C+ CP PG+EA+R++CP G GY
Sbjct: 679 GPGTC--TLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHGY 730



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 44/129 (34%), Positives = 56/129 (43%), Gaps = 14/129 (10%)

Query: 85  CSVGAAWGNYCDP--CPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC 142
           C+ GA   N C P  C     + YR +C   PGYQ  L P     T  D +EC   +   
Sbjct: 848 CAAGAT--NVCGPGTCVNL-PDGYRCVC--SPGYQ--LHPSQAYCT--DDNECL-RDPCK 897

Query: 143 AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX--RPDVCGPGVCRNLPGSYVCLCP 200
             G C N  GS+ C C  G++LA               +P VC  G C N  GSY C C 
Sbjct: 898 GKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECD 957

Query: 201 EGYVAMPNG 209
           +GY+ +  G
Sbjct: 958 QGYIMVRKG 966



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 41/101 (40%), Positives = 49/101 (48%), Gaps = 13/101 (12%)

Query: 71  SDELSEDGTMAACCCSVGAAWG-NYCDPCP-EPGSEAYR--QL-CPGGPGYQPVLEPPSY 125
           ++ L E  T   CC SVGA WG   C PCP  P S      QL CP   GY+ +      
Sbjct: 564 ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECP--QGYKRL-----N 616

Query: 126 VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
           +    DI+EC    GLC    C NT GS++CTC  G  L P
Sbjct: 617 LTHCQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDP 656



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 126 VVTLAD--IDECAAHE-GLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +VTL+   ID CAA    +C  GTC N    + C C  G+ L P            R   
Sbjct: 837 LVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPC 896

Query: 183 CGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQNLS 218
            G G C N  GSY C C  GY    +G+    Q+++
Sbjct: 897 KGKGRCINRVGSYSCFCYPGYTLATSGATQECQDIN 932



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 19/39 (48%), Positives = 24/39 (61%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDG 44
           C D++EC+ P  C  GQC NT+GSY C C   Y +V  G
Sbjct: 928 CQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKG 966



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTA--CYD 49
           CTD +EC        G+CIN  GSY+C C P Y L + G    C D
Sbjct: 885 CTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQD 930



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 9   VDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA---RCYGK 58
           +D C +  +  C  G C+N    Y C C P Y+L      C D  +     C GK
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGK 899


>AC019195-1|AAY14953.1|  546|Homo sapiens unknown protein.
          Length = 546

 Score = 93.9 bits (223), Expect = 4e-19
 Identities = 45/117 (38%), Positives = 59/117 (50%), Gaps = 11/117 (9%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCP------PNYELVSDGTACYDSRKARCYGKV 59
           C D++EC+    C  G+C+NT GSY C C       P +             K  CY  V
Sbjct: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLV 357

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
              SG +       LS   T   CCCSVG AWG +C+ CP PG+ A++++CPGG GY
Sbjct: 358 S--SGRQCMHP---LSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGY 409



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 8/86 (9%)

Query: 83  CCCSVGAAWG-NYCDPCPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
           CC +VG +WG N C  CP+ P    Y Q+    PGY+ V           DI+EC   +G
Sbjct: 255 CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN-----TFCQDINECQL-QG 308

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAP 166
           +C +G C NT GS+ CTC  G+   P
Sbjct: 309 VCPNGECLNTMGSYRCTCKIGFGPDP 334


>S54426-1|AAB25244.1|  109|Homo sapiens fibrillin protein.
          Length = 109

 Score = 84.6 bits (200), Expect = 3e-16
 Identities = 43/114 (37%), Positives = 57/114 (50%), Gaps = 8/114 (7%)

Query: 88  GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTC 147
           G  WG+ C+ CP    EA+RQ+CP G G   ++ P    V   D+DEC   + +C HG C
Sbjct: 4   GEGWGDPCELCPTEPDEAFRQICPYGSGI--IVGPDDSAV---DMDECKEPD-VCKHGQC 57

Query: 148 TNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPE 201
            NT GS+ C C  G+ LA              P  CG G C+N+ G + C C E
Sbjct: 58  INTDGSYRCECPFGYILAGNECVDTDECSVGNP--CGNGTCKNVIGGFECTCEE 109



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/49 (51%), Positives = 30/49 (61%), Gaps = 2/49 (4%)

Query: 2  PGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDS 50
          P  +  D+DECK P  C++GQCINT GSY C CP  Y L   G  C D+
Sbjct: 36 PDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDT 82



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 1/54 (1%)

Query: 155 VCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
           +C  G+G  + P             PDVC  G C N  GSY C CP GY+   N
Sbjct: 25  ICPYGSGIIVGPDDSAVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYILAGN 77



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/34 (38%), Positives = 15/34 (44%)

Query: 1   MPGFNCTDVDECKSPQSCQYGQCINTQGSYTCRC 34
           + G  C D DEC     C  G C N  G + C C
Sbjct: 74  LAGNECVDTDECSVGNPCGNGTCKNVIGGFECTC 107


>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
          Length = 5636

 Score = 80.6 bits (190), Expect = 4e-15
 Identities = 69/228 (30%), Positives = 97/228 (42%), Gaps = 24/228 (10%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYG---- 57
            G  C D+DEC+  P+ C + QC NT GS+ C CPP   L+ DG +C    +   YG    
Sbjct: 5311 GRPCMDIDECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYS 5369

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
              +L +     R++ +  +     +   S  + + N             R+ CP G    
Sbjct: 5370 SYNL-ARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRT-RRTIRKTCPEG---- 5423

Query: 118  PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
                  S+  T  DIDEC  +   C H  C NTFGS+ C C  G+ L             
Sbjct: 5424 ---SEASH-DTCVDIDEC-ENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5477

Query: 178  XRPDV-CGPG-VCRNLPGSYVCL---CPEGYVAMPNGSQYLLQNLSTN 220
               +V CGP  +C N+ GSY C+   CP  Y   P  S + L+N   N
Sbjct: 5478 LEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDP-VSGFCLKNCPPN 5524



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 65/221 (29%), Positives = 82/221 (37%), Gaps = 25/221 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKAR---- 54
            G  C D+DEC     +C  GQ C NT GSY C  RC   +   SDG +C D  + +    
Sbjct: 5143 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 5202

Query: 55   CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP---CPEP-GSEAYRQLC 110
            C+ +     G+  C         G     C  V     N C P   C    G      LC
Sbjct: 5203 CHQRCFNAIGSFHCGCEPGYQLKGRK---CMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 5259

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW-SLAPXX 168
            P G          +   T  DIDEC      C +   C NT  S+ C C  G+ S     
Sbjct: 5260 PNGM-------TKAENGTCIDIDECKDGTHQCRYNQICENTRSSYRCVCPRGYRSQGVGR 5312

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       P  C    C N PGS+ C+CP G   + +G
Sbjct: 5313 PCMDIDECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDG 5352



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 53/211 (25%), Positives = 71/211 (33%), Gaps = 24/211 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D DEC +   C +  C N  G+Y C CP    + +DG  C D  +           G 
Sbjct: 5106 CADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECAL--------GR 5156

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-----GNYCDPCPE-PGSEAYRQLCPGGPGYQPV 119
             TC    +         C    G+ +     G  C    E   S    Q C    G    
Sbjct: 5157 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 5216

Query: 120  LEPPSYVV---TLADIDECAAHEGLCAHGT-CTNTFGSFVC--TCGAGWSLAPXXXXXXX 173
               P Y +      D++EC   + +C     C NT G + C   C  G + A        
Sbjct: 5217 GCEPGYQLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDI 5274

Query: 174  XXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
                     C    +C N   SY C+CP GY
Sbjct: 5275 DECKDGTHQCRYNQICENTRSSYRCVCPRGY 5305



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 44/155 (28%), Positives = 58/155 (37%), Gaps = 21/155 (13%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKARCYG 57
            + G  C DV+EC+    C+  Q C NT+G Y C   CP       +GT         C  
Sbjct: 5224 LKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT---------CID 5273

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYC---DPCPEPGSEAYRQLCP 111
              + + GT  CR +       +   C C  G      G  C   D C +       Q C 
Sbjct: 5274 IDECKDGTHQCRYNQICENTRSSYRCVCPRGYRSQGVGRPCMDIDECEQVPKPCAHQ-CS 5332

Query: 112  GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT 146
              PG    + PP   + L D   CA  E L  +GT
Sbjct: 5333 NTPGSFKCICPPGQHL-LGDGKSCAGLERLPNYGT 5366



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 6/84 (7%)

Query: 130  ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCGPGV- 187
            AD DECAA    C+H +C N  G++ C+C  G ++A                  C  G  
Sbjct: 5107 ADEDECAAGNP-CSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQD 5164

Query: 188  CRNLPGSYVCL--CPEGYVAMPNG 209
            C N  GSY C+  C  G+    +G
Sbjct: 5165 CDNTIGSYRCVVRCGSGFRRTSDG 5188


>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
          Length = 1235

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 65/210 (30%), Positives = 85/210 (40%), Gaps = 28/210 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C TDV+EC  P  CQ+G  C+N  GSY C+CP  +     G  C DS    C     
Sbjct: 176 GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-DSLYVPCAPSPC 230

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGY 116
           +  G  TCR + + + +     C C  G   G+ C    D CP    +    +C  G   
Sbjct: 231 VNGG--TCRQTGDFTFE-----CNCLPGFE-GSTCERNIDDCPNHRCQ-NGGVCVDGVNT 281

Query: 117 QPVLEPPSYV--VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP +       D+DEC      C + GTC N  G + C C  GWS          
Sbjct: 282 YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDD 341

Query: 174 XXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                    C PG  C +   S+ C+CPEG
Sbjct: 342 CAFAS----CTPGSTCIDRVASFSCMCPEG 367



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 55/204 (26%), Positives = 74/204 (36%), Gaps = 20/204 (9%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C+D +DEC S      G+CI+    Y C C P    V+      D     C   + +
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQLCPGGPGYQPV 119
             G    R S   S   T   C   +     N C        G   +R +CP GP +   
Sbjct: 661 -DGIN--RYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHH--- 714

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
             P  Y    + ++EC ++   C HG CT     + C C AGW                 
Sbjct: 715 --PSCY----SQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW--VGINCEVDKNECLSN 764

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P   G G C NL   Y C C +G+
Sbjct: 765 PCQNG-GTCDNLVNGYRCTCKKGF 787



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 63/233 (27%), Positives = 89/233 (38%), Gaps = 38/233 (16%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY------ELVSD--------GTAC 47
            G  CT D+DEC S     +G C NTQGSY C CPP +      E + D        G +C
Sbjct: 867  GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSC 926

Query: 48   YD---SRKARCYG-------KVDLRSG-TETCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
             D   +    C         + D+    +E C++    S+      C C  G   G +C+
Sbjct: 927  MDGVNTFSCLCLPGFTGDKYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD-GVHCE 985

Query: 97   ----PCPEPGSEAYRQLCPGGPGYQPVLEPPSYV--VTLADIDECAAHEGLCAHGTCTNT 150
                 C E  S      C  G      L P  +     L +I+EC++H  L   GTC + 
Sbjct: 986  NNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCL-NEGTCVDG 1043

Query: 151  FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G++ C+C  G++               R      G C        CLCP G+
Sbjct: 1044 LGTYRCSCPLGYT---GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 58/215 (26%), Positives = 84/215 (39%), Gaps = 36/215 (16%)

Query: 3   GFNCT-DVDECKSPQS--CQY-GQCINTQGSYTCRCPPNY---ELVSDGTACYD---SRK 52
           G +CT DVDEC    S  C++ G+C+NT G++ C C   Y       D   C+       
Sbjct: 409 GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468

Query: 53  ARCYGKVDLRSGTETCRDSDELSEDGTMAACC-CSVGAAWGNYCDPCPEPGSEAYRQLCP 111
           A C  K+    G  TC     L   G     C   +     N C    +   +  R  C 
Sbjct: 469 ATCLDKI----GGFTC-----LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519

Query: 112 GGPGYQ-PVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXX 169
             PG+  PV +         DID+C++    C +G  C +    + C C  G++      
Sbjct: 520 CPPGFTGPVCQ--------IDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFT----GV 565

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                     PD C  G C++   SY C+C  GY+
Sbjct: 566 LCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM 600



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 62/209 (29%), Positives = 78/209 (37%), Gaps = 28/209 (13%)

Query: 6   CT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVDL 61
           CT DVDEC   P +CQ G  C N  G Y C C   +          D   A C  G   +
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI 354

Query: 62  -RSGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
            R  + +C   +   + G +      C S     G  CD  P  G   Y   CP G    
Sbjct: 355 DRVASFSCMCPE--GKAGLLCHLDDACISNPCHKGALCDTNPLNGQ--YICTCPQGYKGA 410

Query: 118 PVLEPPSYVVTLADIDECA-AHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
              E         D+DECA A+   C H G C NT G+F C C  G++  P         
Sbjct: 411 DCTE---------DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA-GP---RCEMDI 457

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                D C     C +  G + CLC  G+
Sbjct: 458 NECHSDPCQNDATCLDKIGGFTCLCMPGF 486



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 7/83 (8%)

Query: 133 DECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRN 190
           D C +H   CA+G TCT     F C C  G++                P  C  G  C N
Sbjct: 146 DACLSHP--CANGSTCTTVANQFSCKCLTGFT---GQKCETDVNECDIPGHCQHGGTCLN 200

Query: 191 LPGSYVCLCPEGYVAMPNGSQYL 213
           LPGSY C CP+G+      S Y+
Sbjct: 201 LPGSYQCQCPQGFTGQYCDSLYV 223



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 51/215 (23%), Positives = 81/215 (37%), Gaps = 35/215 (16%)

Query: 1   MPGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           MPGF   +C  +++EC+S      GQC++    + C CPP +     G  C         
Sbjct: 483 MPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGPVC--------- 529

Query: 57  GKVDLRSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEAYRQLC 110
            ++D+   + T C +  +  +      C C+ G   G  C    D C P+P    +   C
Sbjct: 530 -QIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFT-GVLCEENIDNCDPDP---CHHGQC 584

Query: 111 PGGPGYQPVLEPPSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXX 168
             G      +  P Y+  +    IDEC +   L   G C +    + C C  G S     
Sbjct: 585 QDGIDSYTCICNPGYMGAICSDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPGTS----G 639

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                       + C  G+C +    Y C+C  G+
Sbjct: 640 VNCEINFDDCASNPCIHGICMDGINRYSCVCSPGF 674



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 58/208 (27%), Positives = 76/208 (36%), Gaps = 24/208 (11%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  D +EC S      G C N    Y C C   ++    G  C       C     L
Sbjct: 751 GINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK----GYNC-QVNIDECASNPCL 805

Query: 62  RSGTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPC-PEPGSEAYRQLCPGGPGYQ-- 117
             G  TC   D++S  G    C     G        PC P P   A   +C   P ++  
Sbjct: 806 NQG--TC--FDDIS--GYTCHCVLPYTGKNCQTVLAPCSPNPCENA--AVCKESPNFESY 857

Query: 118 PVLEPPSY--VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             L  P +       DIDEC + +    HG C NT GS++C C  G+S            
Sbjct: 858 TCLCAPGWQGQRCTIDIDECIS-KPCMNHGLCHNTQGSYMCECPPGFS--GMDCEEDIDD 914

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C +   ++ CLC  G+
Sbjct: 915 CLANPCQNG-GSCMDGVNTFSCLCLPGF 941



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 28/210 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G+NC  ++DEC S      G C +    YTC C   Y     G  C  +  A C    + 
Sbjct: 789 GYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPY----TGKNC-QTVLAPC--SPNP 841

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGY 116
                 C++S           C C+ G  W G  C    D C       +  LC    G 
Sbjct: 842 CENAAVCKESPNFES----YTCLCAPG--WQGQRCTIDIDECISKPCMNH-GLCHNTQGS 894

Query: 117 QPVLEPPSY--VVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP +  +    DID+C A+   C + G+C +   +F C C  G++          
Sbjct: 895 YMCECPPGFSGMDCEEDIDDCLANP--CQNGGSCMDGVNTFSCLCLPGFT--GDKYQTDM 950

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                 P   G G C +   SY C C  G+
Sbjct: 951 NECLSEPCKNG-GTCSDYVNSYTCKCQAGF 979



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 51/211 (24%), Positives = 77/211 (36%), Gaps = 35/211 (16%)

Query: 8    DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
            +++EC S      G C++  G+Y C CP  Y                C   V+L S +  
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYT------------GKNCQTLVNLCSRSP- 1071

Query: 68   CRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEA---------YRQLCPGGP 114
            C++     +    + C C  G A G YCD     C    S           +  +C    
Sbjct: 1072 CKNKGTCVQKKAESQCLCPSGWA-GAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130

Query: 115  GYQPVLEPPSYVVTLAD--IDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
                   P  Y  +  +  +DECA++   C HG TC++  G + C C  G+         
Sbjct: 1131 NTHYCQCPLGYTGSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQ--GVNCEY 1186

Query: 172  XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                   +P   G G C +L   + C CP G
Sbjct: 1187 EVDECQNQPCQNG-GTCIDLVNHFKCSCPPG 1216



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 56/218 (25%), Positives = 73/218 (33%), Gaps = 29/218 (13%)

Query: 1    MPGFNC----TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            +PGF      TD++EC S      G C +   SYTC+C   +    DG  C ++    C 
Sbjct: 938  LPGFTGDKYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----DGVHC-ENNINECT 992

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC-DPCPEPGSE--AYRQLCPGG 113
                   G  TC D           +C C VG   G++C     E  S        C  G
Sbjct: 993  ESSCFNGG--TCVDGI------NSFSCLCPVGFT-GSFCLHEINECSSHPCLNEGTCVDG 1043

Query: 114  PGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLA----PXX 168
             G      P  Y                C + GTC        C C +GW+ A    P  
Sbjct: 1044 LGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNV 1103

Query: 169  X--XXXXXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                           +C   GVC N   ++ C CP GY
Sbjct: 1104 SCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY 1141



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 53/217 (24%), Positives = 75/217 (34%), Gaps = 34/217 (15%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C  +++EC        G C++   S++C CP  +     G+ C       C     L
Sbjct: 981  GVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFT----GSFCLHEIN-ECSSHPCL 1035

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGN------YCD--PCPEPGSEAYRQ----- 108
              GT  C D       GT   C C +G    N       C   PC   G+   ++     
Sbjct: 1036 NEGT--CVDGL-----GTYR-CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQC 1087

Query: 109  LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPX 167
            LCP G       + P+    +A        E LC H G C N   +  C C  G++    
Sbjct: 1088 LCPSGWA-GAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT---- 1142

Query: 168  XXXXXXXXXXXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
                         + C  G  C +  G Y C C  GY
Sbjct: 1143 GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 50/209 (23%), Positives = 72/209 (34%), Gaps = 25/209 (11%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G  C   D C S        C      ++C+C   +     G  C ++    C      +
Sbjct: 139 GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKC-ETDVNECDIPGHCQ 193

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PC-PEPGSEAYRQLCPGGPGYQ 117
            G  TC     L+  G+   C C  G   G YCD    PC P P          G   ++
Sbjct: 194 HGG-TC-----LNLPGSYQ-CQCPQGFT-GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 245

Query: 118 PVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               P     T   +ID+C  H   C +G  C +   ++ C C   W+            
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHR--CQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDE 301

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
              +P+ C   G C N  G Y C+C  G+
Sbjct: 302 CLLQPNACQNGGTCANRNGGYGCVCVNGW 330



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 3/56 (5%)

Query: 151 FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           F S+ C C  GW                +P +   G+C N  GSY+C CP G+  M
Sbjct: 854 FESYTCLCAPGWQ--GQRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGFSGM 906



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 3/36 (8%)

Query: 3    GFNCT-DVDECKSPQSCQYG-QCINTQGSYTCRCPP 36
            G NC  +VDEC++ Q CQ G  CI+    + C CPP
Sbjct: 1181 GVNCEYEVDECQN-QPCQNGGTCIDLVNHFKCSCPP 1215



 Score = 34.3 bits (75), Expect = 0.36
 Identities = 44/171 (25%), Positives = 58/171 (33%), Gaps = 23/171 (13%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC T V+ C        G C+  +    C CP  +     G  C D     C      
Sbjct: 1057 GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWA----GAYC-DVPNVSCDIAASR 1111

Query: 62   RSGT--ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP----- 114
            R       C+ S      G    C C +G   G+YC+   E   E     C  G      
Sbjct: 1112 RGVLVEHLCQHSGVCINAGNTHYCQCPLGYT-GSYCE---EQLDECASNPCQHGATCSDF 1167

Query: 115  --GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAG 161
              GY+    P    V    ++DEC      C +G TC +    F C+C  G
Sbjct: 1168 IGGYRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG 1216


>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2
           (Drosophila) protein.
          Length = 2471

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 65/210 (30%), Positives = 85/210 (40%), Gaps = 28/210 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C TDV+EC  P  CQ+G  C+N  GSY C+CP  +     G  C DS    C     
Sbjct: 176 GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-DSLYVPCAPSPC 230

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGY 116
           +  G  TCR + + + +     C C  G   G+ C    D CP    +    +C  G   
Sbjct: 231 VNGG--TCRQTGDFTFE-----CNCLPGFE-GSTCERNIDDCPNHRCQ-NGGVCVDGVNT 281

Query: 117 QPVLEPPSYV--VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP +       D+DEC      C + GTC N  G + C C  GWS          
Sbjct: 282 YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDD 341

Query: 174 XXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                    C PG  C +   S+ C+CPEG
Sbjct: 342 CAFAS----CTPGSTCIDRVASFSCMCPEG 367



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 55/204 (26%), Positives = 74/204 (36%), Gaps = 20/204 (9%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C+D +DEC S      G+CI+    Y C C P    V+      D     C   + +
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQLCPGGPGYQPV 119
             G    R S   S   T   C   +     N C        G   +R +CP GP +   
Sbjct: 661 -DGIN--RYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHH--- 714

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
             P  Y    + ++EC ++   C HG CT     + C C AGW                 
Sbjct: 715 --PSCY----SQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW--VGINCEVDKNECLSN 764

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P   G G C NL   Y C C +G+
Sbjct: 765 PCQNG-GTCDNLVNGYRCTCKKGF 787



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 63/233 (27%), Positives = 89/233 (38%), Gaps = 38/233 (16%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY------ELVSD--------GTAC 47
            G  CT D+DEC S     +G C NTQGSY C CPP +      E + D        G +C
Sbjct: 867  GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSC 926

Query: 48   YD---SRKARCYG-------KVDLRSG-TETCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
             D   +    C         + D+    +E C++    S+      C C  G   G +C+
Sbjct: 927  MDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD-GVHCE 985

Query: 97   ----PCPEPGSEAYRQLCPGGPGYQPVLEPPSYV--VTLADIDECAAHEGLCAHGTCTNT 150
                 C E  S      C  G      L P  +     L +I+EC++H  L   GTC + 
Sbjct: 986  NNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCL-NEGTCVDG 1043

Query: 151  FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G++ C+C  G++               R      G C        CLCP G+
Sbjct: 1044 LGTYRCSCPLGYT---GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 58/215 (26%), Positives = 84/215 (39%), Gaps = 36/215 (16%)

Query: 3   GFNCT-DVDECKSPQS--CQY-GQCINTQGSYTCRCPPNY---ELVSDGTACYD---SRK 52
           G +CT DVDEC    S  C++ G+C+NT G++ C C   Y       D   C+       
Sbjct: 409 GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468

Query: 53  ARCYGKVDLRSGTETCRDSDELSEDGTMAACC-CSVGAAWGNYCDPCPEPGSEAYRQLCP 111
           A C  K+    G  TC     L   G     C   +     N C    +   +  R  C 
Sbjct: 469 ATCLDKI----GGFTC-----LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519

Query: 112 GGPGYQ-PVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXX 169
             PG+  PV +         DID+C++    C +G  C +    + C C  G++      
Sbjct: 520 CPPGFTGPVCQ--------IDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFT----GV 565

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                     PD C  G C++   SY C+C  GY+
Sbjct: 566 LCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM 600



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 62/209 (29%), Positives = 78/209 (37%), Gaps = 28/209 (13%)

Query: 6   CT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVDL 61
           CT DVDEC   P +CQ G  C N  G Y C C   +          D   A C  G   +
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI 354

Query: 62  -RSGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
            R  + +C   +   + G +      C S     G  CD  P  G   Y   CP G    
Sbjct: 355 DRVASFSCMCPE--GKAGLLCHLDDACISNPCHKGALCDTNPLNGQ--YICTCPQGYKGA 410

Query: 118 PVLEPPSYVVTLADIDECA-AHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
              E         D+DECA A+   C H G C NT G+F C C  G++  P         
Sbjct: 411 DCTE---------DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA-GP---RCEMDI 457

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                D C     C +  G + CLC  G+
Sbjct: 458 NECHSDPCQNDATCLDKIGGFTCLCMPGF 486



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 7/83 (8%)

Query: 133 DECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRN 190
           D C +H   CA+G TCT     F C C  G++                P  C  G  C N
Sbjct: 146 DACLSHP--CANGSTCTTVANQFSCKCLTGFT---GQKCETDVNECDIPGHCQHGGTCLN 200

Query: 191 LPGSYVCLCPEGYVAMPNGSQYL 213
           LPGSY C CP+G+      S Y+
Sbjct: 201 LPGSYQCQCPQGFTGQYCDSLYV 223



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 51/215 (23%), Positives = 81/215 (37%), Gaps = 35/215 (16%)

Query: 1   MPGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           MPGF   +C  +++EC+S      GQC++    + C CPP +     G  C         
Sbjct: 483 MPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGPVC--------- 529

Query: 57  GKVDLRSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEAYRQLC 110
            ++D+   + T C +  +  +      C C+ G   G  C    D C P+P    +   C
Sbjct: 530 -QIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFT-GVLCEENIDNCDPDP---CHHGQC 584

Query: 111 PGGPGYQPVLEPPSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXX 168
             G      +  P Y+  +    IDEC +   L   G C +    + C C  G S     
Sbjct: 585 QDGIDSYTCICNPGYMGAICSDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPGTS----G 639

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                       + C  G+C +    Y C+C  G+
Sbjct: 640 VNCEINFDDCASNPCIHGICMDGINRYSCVCSPGF 674



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 58/208 (27%), Positives = 76/208 (36%), Gaps = 24/208 (11%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  D +EC S      G C N    Y C C   ++    G  C       C     L
Sbjct: 751 GINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK----GYNC-QVNIDECASNPCL 805

Query: 62  RSGTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPC-PEPGSEAYRQLCPGGPGYQ-- 117
             G  TC   D++S  G    C     G        PC P P   A   +C   P ++  
Sbjct: 806 NQG--TC--FDDIS--GYTCHCVLPYTGKNCQTVLAPCSPNPCENA--AVCKESPNFESY 857

Query: 118 PVLEPPSY--VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             L  P +       DIDEC + +    HG C NT GS++C C  G+S            
Sbjct: 858 TCLCAPGWQGQRCTIDIDECIS-KPCMNHGLCHNTQGSYMCECPPGFS--GMDCEEDIDD 914

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C +   ++ CLC  G+
Sbjct: 915 CLANPCQNG-GSCMDGVNTFSCLCLPGF 941



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 28/210 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G+NC  ++DEC S      G C +    YTC C   Y     G  C  +  A C    + 
Sbjct: 789 GYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPY----TGKNC-QTVLAPC--SPNP 841

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGY 116
                 C++S           C C+ G  W G  C    D C       +  LC    G 
Sbjct: 842 CENAAVCKESPNFES----YTCLCAPG--WQGQRCTIDIDECISKPCMNH-GLCHNTQGS 894

Query: 117 QPVLEPPSY--VVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP +  +    DID+C A+   C + G+C +   +F C C  G++          
Sbjct: 895 YMCECPPGFSGMDCEEDIDDCLANP--CQNGGSCMDGVNTFSCLCLPGFT--GDKCQTDM 950

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                 P   G G C +   SY C C  G+
Sbjct: 951 NECLSEPCKNG-GTCSDYVNSYTCKCQAGF 979



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 51/211 (24%), Positives = 76/211 (36%), Gaps = 35/211 (16%)

Query: 8    DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
            +++EC S      G C++  G+Y C CP  Y                C   V+L S    
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGY------------TGKNCQTLVNLCS-RSP 1071

Query: 68   CRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSE---------AYRQLCPGGP 114
            C++     +    + C C  G A G YCD     C    S           +  +C    
Sbjct: 1072 CKNKGTCVQKKAESQCLCPSGWA-GAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130

Query: 115  GYQPVLEPPSYVVTLAD--IDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
                   P  Y  +  +  +DECA++   C HG TC++  G + C C  G+         
Sbjct: 1131 NTHYCQCPLGYTGSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQ--GVNCEY 1186

Query: 172  XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                   +P   G G C +L   + C CP G
Sbjct: 1187 EVDECQNQPCQNG-GTCIDLVNHFKCSCPPG 1216



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 57/218 (26%), Positives = 74/218 (33%), Gaps = 29/218 (13%)

Query: 1    MPGFN---C-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            +PGF    C TD++EC S      G C +   SYTC+C   +    DG  C ++    C 
Sbjct: 938  LPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----DGVHC-ENNINECT 992

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC-DPCPEPGSE--AYRQLCPGG 113
                   G  TC D           +C C VG   G++C     E  S        C  G
Sbjct: 993  ESSCFNGG--TCVDGI------NSFSCLCPVGFT-GSFCLHEINECSSHPCLNEGTCVDG 1043

Query: 114  PGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLA----PXX 168
             G      P  Y                C + GTC        C C +GW+ A    P  
Sbjct: 1044 LGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNV 1103

Query: 169  X--XXXXXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                           +C   GVC N   ++ C CP GY
Sbjct: 1104 SCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY 1141



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 52/213 (24%), Positives = 68/213 (31%), Gaps = 25/213 (11%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC T V+ C        G C+  +    C CP  +     G  C D     C      
Sbjct: 1057 GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWA----GAYC-DVPNVSCDIAASR 1111

Query: 62   RSGT--ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP----- 114
            R       C+ S      G    C C +G   G+YC+   E   E     C  G      
Sbjct: 1112 RGVLVEHLCQHSGVCINAGNTHYCQCPLGYT-GSYCE---EQLDECASNPCQHGATCSDF 1167

Query: 115  --GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXX 170
              GY+    P    V    ++DEC      C +G TC +    F C+C  G         
Sbjct: 1168 IGGYRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG--TRGLLCE 1223

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                     P     G C +  G Y C C  G+
Sbjct: 1224 ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF 1256



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 50/209 (23%), Positives = 72/209 (34%), Gaps = 25/209 (11%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G  C   D C S        C      ++C+C   +     G  C ++    C      +
Sbjct: 139 GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKC-ETDVNECDIPGHCQ 193

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PC-PEPGSEAYRQLCPGGPGYQ 117
            G  TC     L+  G+   C C  G   G YCD    PC P P          G   ++
Sbjct: 194 HGG-TC-----LNLPGSYQ-CQCPQGFT-GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 245

Query: 118 PVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               P     T   +ID+C  H   C +G  C +   ++ C C   W+            
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHR--CQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDE 301

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
              +P+ C   G C N  G Y C+C  G+
Sbjct: 302 CLLQPNACQNGGTCANRNGGYGCVCVNGW 330



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 3/56 (5%)

Query: 151 FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           F S+ C C  GW                +P +   G+C N  GSY+C CP G+  M
Sbjct: 854 FESYTCLCAPGWQ--GQRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGFSGM 906



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 37/147 (25%), Positives = 50/147 (34%), Gaps = 12/147 (8%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCI---NTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
            G +C T VD C        G C    N    + CRCPP +      ++C   +  +    
Sbjct: 1298 GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQC 1357

Query: 59   VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCP-GGPGYQ 117
            V   SG      S    E G     C S     G  C P  +P   + +   P  G   +
Sbjct: 1358 VHTASGPRCFCPSPRDCESG-----CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412

Query: 118  PVLEPPSYVVTLADIDECA--AHEGLC 142
                PPS          CA  A +G+C
Sbjct: 1413 LYTAPPSTPPATCLSQYCADKARDGVC 1439


>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2
           (Drosophila) protein.
          Length = 2471

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 65/210 (30%), Positives = 85/210 (40%), Gaps = 28/210 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C TDV+EC  P  CQ+G  C+N  GSY C+CP  +     G  C DS    C     
Sbjct: 176 GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-DSLYVPCAPSPC 230

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGY 116
           +  G  TCR + + + +     C C  G   G+ C    D CP    +    +C  G   
Sbjct: 231 VNGG--TCRQTGDFTFE-----CNCLPGFE-GSTCERNIDDCPNHRCQ-NGGVCVDGVNT 281

Query: 117 QPVLEPPSYV--VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP +       D+DEC      C + GTC N  G + C C  GWS          
Sbjct: 282 YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDD 341

Query: 174 XXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                    C PG  C +   S+ C+CPEG
Sbjct: 342 CAFAS----CTPGSTCIDRVASFSCMCPEG 367



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 55/204 (26%), Positives = 74/204 (36%), Gaps = 20/204 (9%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C+D +DEC S      G+CI+    Y C C P    V+      D     C   + +
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQLCPGGPGYQPV 119
             G    R S   S   T   C   +     N C        G   +R +CP GP +   
Sbjct: 661 -DGIN--RYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHH--- 714

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
             P  Y    + ++EC ++   C HG CT     + C C AGW                 
Sbjct: 715 --PSCY----SQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW--VGINCEVDKNECLSN 764

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P   G G C NL   Y C C +G+
Sbjct: 765 PCQNG-GTCDNLVNGYRCTCKKGF 787



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 63/233 (27%), Positives = 89/233 (38%), Gaps = 38/233 (16%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY------ELVSD--------GTAC 47
            G  CT D+DEC S     +G C NTQGSY C CPP +      E + D        G +C
Sbjct: 867  GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSC 926

Query: 48   YD---SRKARCYG-------KVDLRSG-TETCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
             D   +    C         + D+    +E C++    S+      C C  G   G +C+
Sbjct: 927  MDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD-GVHCE 985

Query: 97   ----PCPEPGSEAYRQLCPGGPGYQPVLEPPSYV--VTLADIDECAAHEGLCAHGTCTNT 150
                 C E  S      C  G      L P  +     L +I+EC++H  L   GTC + 
Sbjct: 986  NNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCL-NEGTCVDG 1043

Query: 151  FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G++ C+C  G++               R      G C        CLCP G+
Sbjct: 1044 LGTYRCSCPLGYT---GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 58/215 (26%), Positives = 84/215 (39%), Gaps = 36/215 (16%)

Query: 3   GFNCT-DVDECKSPQS--CQY-GQCINTQGSYTCRCPPNY---ELVSDGTACYD---SRK 52
           G +CT DVDEC    S  C++ G+C+NT G++ C C   Y       D   C+       
Sbjct: 409 GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468

Query: 53  ARCYGKVDLRSGTETCRDSDELSEDGTMAACC-CSVGAAWGNYCDPCPEPGSEAYRQLCP 111
           A C  K+    G  TC     L   G     C   +     N C    +   +  R  C 
Sbjct: 469 ATCLDKI----GGFTC-----LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519

Query: 112 GGPGYQ-PVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXX 169
             PG+  PV +         DID+C++    C +G  C +    + C C  G++      
Sbjct: 520 CPPGFTGPVCQ--------IDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFT----GV 565

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                     PD C  G C++   SY C+C  GY+
Sbjct: 566 LCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM 600



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 62/209 (29%), Positives = 78/209 (37%), Gaps = 28/209 (13%)

Query: 6   CT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVDL 61
           CT DVDEC   P +CQ G  C N  G Y C C   +          D   A C  G   +
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI 354

Query: 62  -RSGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
            R  + +C   +   + G +      C S     G  CD  P  G   Y   CP G    
Sbjct: 355 DRVASFSCMCPE--GKAGLLCHLDDACISNPCHKGALCDTNPLNGQ--YICTCPQGYKGA 410

Query: 118 PVLEPPSYVVTLADIDECA-AHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
              E         D+DECA A+   C H G C NT G+F C C  G++  P         
Sbjct: 411 DCTE---------DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA-GP---RCEMDI 457

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                D C     C +  G + CLC  G+
Sbjct: 458 NECHSDPCQNDATCLDKIGGFTCLCMPGF 486



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 7/83 (8%)

Query: 133 DECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRN 190
           D C +H   CA+G TCT     F C C  G++                P  C  G  C N
Sbjct: 146 DACLSHP--CANGSTCTTVANQFSCKCLTGFT---GQKCETDVNECDIPGHCQHGGTCLN 200

Query: 191 LPGSYVCLCPEGYVAMPNGSQYL 213
           LPGSY C CP+G+      S Y+
Sbjct: 201 LPGSYQCQCPQGFTGQYCDSLYV 223



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 51/215 (23%), Positives = 81/215 (37%), Gaps = 35/215 (16%)

Query: 1   MPGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           MPGF   +C  +++EC+S      GQC++    + C CPP +     G  C         
Sbjct: 483 MPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGPVC--------- 529

Query: 57  GKVDLRSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEAYRQLC 110
            ++D+   + T C +  +  +      C C+ G   G  C    D C P+P    +   C
Sbjct: 530 -QIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFT-GVLCEENIDNCDPDP---CHHGQC 584

Query: 111 PGGPGYQPVLEPPSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXX 168
             G      +  P Y+  +    IDEC +   L   G C +    + C C  G S     
Sbjct: 585 QDGIDSYTCICNPGYMGAICSDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPGTS----G 639

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                       + C  G+C +    Y C+C  G+
Sbjct: 640 VNCEINFDDCASNPCIHGICMDGINRYSCVCSPGF 674



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 58/208 (27%), Positives = 76/208 (36%), Gaps = 24/208 (11%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  D +EC S      G C N    Y C C   ++    G  C       C     L
Sbjct: 751 GINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK----GYNC-QVNIDECASNPCL 805

Query: 62  RSGTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPC-PEPGSEAYRQLCPGGPGYQ-- 117
             G  TC   D++S  G    C     G        PC P P   A   +C   P ++  
Sbjct: 806 NQG--TC--FDDIS--GYTCHCVLPYTGKNCQTVLAPCSPNPCENA--AVCKESPNFESY 857

Query: 118 PVLEPPSY--VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             L  P +       DIDEC + +    HG C NT GS++C C  G+S            
Sbjct: 858 TCLCAPGWQGQRCTIDIDECIS-KPCMNHGLCHNTQGSYMCECPPGFS--GMDCEEDIDD 914

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C +   ++ CLC  G+
Sbjct: 915 CLANPCQNG-GSCMDGVNTFSCLCLPGF 941



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 28/210 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G+NC  ++DEC S      G C +    YTC C   Y     G  C  +  A C    + 
Sbjct: 789 GYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPY----TGKNC-QTVLAPC--SPNP 841

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGY 116
                 C++S           C C+ G  W G  C    D C       +  LC    G 
Sbjct: 842 CENAAVCKESPNFES----YTCLCAPG--WQGQRCTIDIDECISKPCMNH-GLCHNTQGS 894

Query: 117 QPVLEPPSY--VVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP +  +    DID+C A+   C + G+C +   +F C C  G++          
Sbjct: 895 YMCECPPGFSGMDCEEDIDDCLANP--CQNGGSCMDGVNTFSCLCLPGFT--GDKCQTDM 950

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                 P   G G C +   SY C C  G+
Sbjct: 951 NECLSEPCKNG-GTCSDYVNSYTCKCQAGF 979



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 51/211 (24%), Positives = 76/211 (36%), Gaps = 35/211 (16%)

Query: 8    DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
            +++EC S      G C++  G+Y C CP  Y                C   V+L S    
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGY------------TGKNCQTLVNLCS-RSP 1071

Query: 68   CRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSE---------AYRQLCPGGP 114
            C++     +    + C C  G A G YCD     C    S           +  +C    
Sbjct: 1072 CKNKGTCVQKKAESQCLCPSGWA-GAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130

Query: 115  GYQPVLEPPSYVVTLAD--IDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
                   P  Y  +  +  +DECA++   C HG TC++  G + C C  G+         
Sbjct: 1131 NTHYCQCPLGYTGSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQ--GVNCEY 1186

Query: 172  XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                   +P   G G C +L   + C CP G
Sbjct: 1187 EVDECQNQPCQNG-GTCIDLVNHFKCSCPPG 1216



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 57/218 (26%), Positives = 74/218 (33%), Gaps = 29/218 (13%)

Query: 1    MPGFN---C-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            +PGF    C TD++EC S      G C +   SYTC+C   +    DG  C ++    C 
Sbjct: 938  LPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----DGVHC-ENNINECT 992

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC-DPCPEPGSE--AYRQLCPGG 113
                   G  TC D           +C C VG   G++C     E  S        C  G
Sbjct: 993  ESSCFNGG--TCVDGI------NSFSCLCPVGFT-GSFCLHEINECSSHPCLNEGTCVDG 1043

Query: 114  PGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLA----PXX 168
             G      P  Y                C + GTC        C C +GW+ A    P  
Sbjct: 1044 LGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNV 1103

Query: 169  X--XXXXXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                           +C   GVC N   ++ C CP GY
Sbjct: 1104 SCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY 1141



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 52/213 (24%), Positives = 68/213 (31%), Gaps = 25/213 (11%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC T V+ C        G C+  +    C CP  +     G  C D     C      
Sbjct: 1057 GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWA----GAYC-DVPNVSCDIAASR 1111

Query: 62   RSGT--ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP----- 114
            R       C+ S      G    C C +G   G+YC+   E   E     C  G      
Sbjct: 1112 RGVLVEHLCQHSGVCINAGNTHYCQCPLGYT-GSYCE---EQLDECASNPCQHGATCSDF 1167

Query: 115  --GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXX 170
              GY+    P    V    ++DEC      C +G TC +    F C+C  G         
Sbjct: 1168 IGGYRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG--TRGLLCE 1223

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                     P     G C +  G Y C C  G+
Sbjct: 1224 ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF 1256



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 50/209 (23%), Positives = 72/209 (34%), Gaps = 25/209 (11%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G  C   D C S        C      ++C+C   +     G  C ++    C      +
Sbjct: 139 GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKC-ETDVNECDIPGHCQ 193

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PC-PEPGSEAYRQLCPGGPGYQ 117
            G  TC     L+  G+   C C  G   G YCD    PC P P          G   ++
Sbjct: 194 HGG-TC-----LNLPGSYQ-CQCPQGFT-GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 245

Query: 118 PVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               P     T   +ID+C  H   C +G  C +   ++ C C   W+            
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHR--CQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDE 301

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
              +P+ C   G C N  G Y C+C  G+
Sbjct: 302 CLLQPNACQNGGTCANRNGGYGCVCVNGW 330



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 3/56 (5%)

Query: 151 FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           F S+ C C  GW                +P +   G+C N  GSY+C CP G+  M
Sbjct: 854 FESYTCLCAPGWQ--GQRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGFSGM 906



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 37/147 (25%), Positives = 50/147 (34%), Gaps = 12/147 (8%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCI---NTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
            G +C T VD C        G C    N    + CRCPP +      ++C   +  +    
Sbjct: 1298 GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQC 1357

Query: 59   VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCP-GGPGYQ 117
            V   SG      S    E G     C S     G  C P  +P   + +   P  G   +
Sbjct: 1358 VHTASGPRCFCPSPRDCESG-----CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412

Query: 118  PVLEPPSYVVTLADIDECA--AHEGLC 142
                PPS          CA  A +G+C
Sbjct: 1413 LYTAPPSTPPATCLSQYCADKARDGVC 1439


>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2
           (Drosophila) protein.
          Length = 2471

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 65/210 (30%), Positives = 85/210 (40%), Gaps = 28/210 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C TDV+EC  P  CQ+G  C+N  GSY C+CP  +     G  C DS    C     
Sbjct: 176 GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-DSLYVPCAPSPC 230

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGY 116
           +  G  TCR + + + +     C C  G   G+ C    D CP    +    +C  G   
Sbjct: 231 VNGG--TCRQTGDFTFE-----CNCLPGFE-GSTCERNIDDCPNHRCQ-NGGVCVDGVNT 281

Query: 117 QPVLEPPSYV--VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP +       D+DEC      C + GTC N  G + C C  GWS          
Sbjct: 282 YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDD 341

Query: 174 XXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                    C PG  C +   S+ C+CPEG
Sbjct: 342 CAFAS----CTPGSTCIDRVASFSCMCPEG 367



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 55/204 (26%), Positives = 74/204 (36%), Gaps = 20/204 (9%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C+D +DEC S      G+CI+    Y C C P    V+      D     C   + +
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQLCPGGPGYQPV 119
             G    R S   S   T   C   +     N C        G   +R +CP GP +   
Sbjct: 661 -DGIN--RYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHH--- 714

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
             P  Y    + ++EC ++   C HG CT     + C C AGW                 
Sbjct: 715 --PSCY----SQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW--VGINCEVDKNECLSN 764

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P   G G C NL   Y C C +G+
Sbjct: 765 PCQNG-GTCDNLVNGYRCTCKKGF 787



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 63/233 (27%), Positives = 89/233 (38%), Gaps = 38/233 (16%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY------ELVSD--------GTAC 47
            G  CT D+DEC S     +G C NTQGSY C CPP +      E + D        G +C
Sbjct: 867  GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSC 926

Query: 48   YD---SRKARCYG-------KVDLRSG-TETCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
             D   +    C         + D+    +E C++    S+      C C  G   G +C+
Sbjct: 927  MDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD-GVHCE 985

Query: 97   ----PCPEPGSEAYRQLCPGGPGYQPVLEPPSYV--VTLADIDECAAHEGLCAHGTCTNT 150
                 C E  S      C  G      L P  +     L +I+EC++H  L   GTC + 
Sbjct: 986  NNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCL-NEGTCVDG 1043

Query: 151  FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G++ C+C  G++               R      G C        CLCP G+
Sbjct: 1044 LGTYRCSCPLGYT---GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 58/215 (26%), Positives = 84/215 (39%), Gaps = 36/215 (16%)

Query: 3   GFNCT-DVDECKSPQS--CQY-GQCINTQGSYTCRCPPNY---ELVSDGTACYD---SRK 52
           G +CT DVDEC    S  C++ G+C+NT G++ C C   Y       D   C+       
Sbjct: 409 GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468

Query: 53  ARCYGKVDLRSGTETCRDSDELSEDGTMAACC-CSVGAAWGNYCDPCPEPGSEAYRQLCP 111
           A C  K+    G  TC     L   G     C   +     N C    +   +  R  C 
Sbjct: 469 ATCLDKI----GGFTC-----LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519

Query: 112 GGPGYQ-PVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXX 169
             PG+  PV +         DID+C++    C +G  C +    + C C  G++      
Sbjct: 520 CPPGFTGPVCQ--------IDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFT----GV 565

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                     PD C  G C++   SY C+C  GY+
Sbjct: 566 LCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM 600



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 62/209 (29%), Positives = 78/209 (37%), Gaps = 28/209 (13%)

Query: 6   CT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVDL 61
           CT DVDEC   P +CQ G  C N  G Y C C   +          D   A C  G   +
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI 354

Query: 62  -RSGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
            R  + +C   +   + G +      C S     G  CD  P  G   Y   CP G    
Sbjct: 355 DRVASFSCMCPE--GKAGLLCHLDDACISNPCHKGALCDTNPLNGQ--YICTCPQGYKGA 410

Query: 118 PVLEPPSYVVTLADIDECA-AHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
              E         D+DECA A+   C H G C NT G+F C C  G++  P         
Sbjct: 411 DCTE---------DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA-GP---RCEMDI 457

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                D C     C +  G + CLC  G+
Sbjct: 458 NECHSDPCQNDATCLDKIGGFTCLCMPGF 486



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 7/83 (8%)

Query: 133 DECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRN 190
           D C +H   CA+G TCT     F C C  G++                P  C  G  C N
Sbjct: 146 DACLSHP--CANGSTCTTVANQFSCKCLTGFT---GQKCETDVNECDIPGHCQHGGTCLN 200

Query: 191 LPGSYVCLCPEGYVAMPNGSQYL 213
           LPGSY C CP+G+      S Y+
Sbjct: 201 LPGSYQCQCPQGFTGQYCDSLYV 223



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 51/215 (23%), Positives = 81/215 (37%), Gaps = 35/215 (16%)

Query: 1   MPGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           MPGF   +C  +++EC+S      GQC++    + C CPP +     G  C         
Sbjct: 483 MPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGPVC--------- 529

Query: 57  GKVDLRSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEAYRQLC 110
            ++D+   + T C +  +  +      C C+ G   G  C    D C P+P    +   C
Sbjct: 530 -QIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFT-GVLCEENIDNCDPDP---CHHGQC 584

Query: 111 PGGPGYQPVLEPPSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXX 168
             G      +  P Y+  +    IDEC +   L   G C +    + C C  G S     
Sbjct: 585 QDGIDSYTCICNPGYMGAICSDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPGTS----G 639

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                       + C  G+C +    Y C+C  G+
Sbjct: 640 VNCEINFDDCASNPCIHGICMDGINRYSCVCSPGF 674



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 58/208 (27%), Positives = 76/208 (36%), Gaps = 24/208 (11%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  D +EC S      G C N    Y C C   ++    G  C       C     L
Sbjct: 751 GINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK----GYNC-QVNIDECASNPCL 805

Query: 62  RSGTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPC-PEPGSEAYRQLCPGGPGYQ-- 117
             G  TC   D++S  G    C     G        PC P P   A   +C   P ++  
Sbjct: 806 NQG--TC--FDDIS--GYTCHCVLPYTGKNCQTVLAPCSPNPCENA--AVCKESPNFESY 857

Query: 118 PVLEPPSY--VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             L  P +       DIDEC + +    HG C NT GS++C C  G+S            
Sbjct: 858 TCLCAPGWQGQRCTIDIDECIS-KPCMNHGLCHNTQGSYMCECPPGFS--GMDCEEDIDD 914

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C +   ++ CLC  G+
Sbjct: 915 CLANPCQNG-GSCMDGVNTFSCLCLPGF 941



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 28/210 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G+NC  ++DEC S      G C +    YTC C   Y     G  C  +  A C    + 
Sbjct: 789 GYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPY----TGKNC-QTVLAPC--SPNP 841

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGY 116
                 C++S           C C+ G  W G  C    D C       +  LC    G 
Sbjct: 842 CENAAVCKESPNFES----YTCLCAPG--WQGQRCTIDIDECISKPCMNH-GLCHNTQGS 894

Query: 117 QPVLEPPSY--VVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP +  +    DID+C A+   C + G+C +   +F C C  G++          
Sbjct: 895 YMCECPPGFSGMDCEEDIDDCLANP--CQNGGSCMDGVNTFSCLCLPGFT--GDKCQTDM 950

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                 P   G G C +   SY C C  G+
Sbjct: 951 NECLSEPCKNG-GTCSDYVNSYTCKCQAGF 979



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 51/211 (24%), Positives = 76/211 (36%), Gaps = 35/211 (16%)

Query: 8    DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
            +++EC S      G C++  G+Y C CP  Y                C   V+L S    
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGY------------TGKNCQTLVNLCS-RSP 1071

Query: 68   CRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSE---------AYRQLCPGGP 114
            C++     +    + C C  G A G YCD     C    S           +  +C    
Sbjct: 1072 CKNKGTCVQKKAESQCLCPSGWA-GAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130

Query: 115  GYQPVLEPPSYVVTLAD--IDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
                   P  Y  +  +  +DECA++   C HG TC++  G + C C  G+         
Sbjct: 1131 NTHYCQCPLGYTGSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQ--GVNCEY 1186

Query: 172  XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                   +P   G G C +L   + C CP G
Sbjct: 1187 EVDECQNQPCQNG-GTCIDLVNHFKCSCPPG 1216



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 57/218 (26%), Positives = 74/218 (33%), Gaps = 29/218 (13%)

Query: 1    MPGFN---C-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            +PGF    C TD++EC S      G C +   SYTC+C   +    DG  C ++    C 
Sbjct: 938  LPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----DGVHC-ENNINECT 992

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC-DPCPEPGSE--AYRQLCPGG 113
                   G  TC D           +C C VG   G++C     E  S        C  G
Sbjct: 993  ESSCFNGG--TCVDGI------NSFSCLCPVGFT-GSFCLHEINECSSHPCLNEGTCVDG 1043

Query: 114  PGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLA----PXX 168
             G      P  Y                C + GTC        C C +GW+ A    P  
Sbjct: 1044 LGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNV 1103

Query: 169  X--XXXXXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                           +C   GVC N   ++ C CP GY
Sbjct: 1104 SCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY 1141



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 52/213 (24%), Positives = 68/213 (31%), Gaps = 25/213 (11%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC T V+ C        G C+  +    C CP  +     G  C D     C      
Sbjct: 1057 GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWA----GAYC-DVPNVSCDIAASR 1111

Query: 62   RSGT--ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP----- 114
            R       C+ S      G    C C +G   G+YC+   E   E     C  G      
Sbjct: 1112 RGVLVEHLCQHSGVCINAGNTHYCQCPLGYT-GSYCE---EQLDECASNPCQHGATCSDF 1167

Query: 115  --GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXX 170
              GY+    P    V    ++DEC      C +G TC +    F C+C  G         
Sbjct: 1168 IGGYRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG--TRGLLCE 1223

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                     P     G C +  G Y C C  G+
Sbjct: 1224 ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF 1256



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 50/209 (23%), Positives = 72/209 (34%), Gaps = 25/209 (11%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G  C   D C S        C      ++C+C   +     G  C ++    C      +
Sbjct: 139 GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKC-ETDVNECDIPGHCQ 193

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PC-PEPGSEAYRQLCPGGPGYQ 117
            G  TC     L+  G+   C C  G   G YCD    PC P P          G   ++
Sbjct: 194 HGG-TC-----LNLPGSYQ-CQCPQGFT-GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 245

Query: 118 PVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               P     T   +ID+C  H   C +G  C +   ++ C C   W+            
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHR--CQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDE 301

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
              +P+ C   G C N  G Y C+C  G+
Sbjct: 302 CLLQPNACQNGGTCANRNGGYGCVCVNGW 330



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 3/56 (5%)

Query: 151 FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           F S+ C C  GW                +P +   G+C N  GSY+C CP G+  M
Sbjct: 854 FESYTCLCAPGWQ--GQRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGFSGM 906



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 37/147 (25%), Positives = 50/147 (34%), Gaps = 12/147 (8%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCI---NTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
            G +C T VD C        G C    N    + CRCPP +      ++C   +  +    
Sbjct: 1298 GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQC 1357

Query: 59   VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCP-GGPGYQ 117
            V   SG      S    E G     C S     G  C P  +P   + +   P  G   +
Sbjct: 1358 VHTASGPRCFCPSPRDCESG-----CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412

Query: 118  PVLEPPSYVVTLADIDECA--AHEGLC 142
                PPS          CA  A +G+C
Sbjct: 1413 LYTAPPSTPPATCLSQYCADKARDGVC 1439


>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
          Length = 2471

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 65/210 (30%), Positives = 85/210 (40%), Gaps = 28/210 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C TDV+EC  P  CQ+G  C+N  GSY C+CP  +     G  C DS    C     
Sbjct: 176 GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-DSLYVPCAPSPC 230

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGY 116
           +  G  TCR + + + +     C C  G   G+ C    D CP    +    +C  G   
Sbjct: 231 VNGG--TCRQTGDFTFE-----CNCLPGFE-GSTCERNIDDCPNHRCQ-NGGVCVDGVNT 281

Query: 117 QPVLEPPSYV--VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP +       D+DEC      C + GTC N  G + C C  GWS          
Sbjct: 282 YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDD 341

Query: 174 XXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                    C PG  C +   S+ C+CPEG
Sbjct: 342 CAFAS----CTPGSTCIDRVASFSCMCPEG 367



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 55/204 (26%), Positives = 74/204 (36%), Gaps = 20/204 (9%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C+D +DEC S      G+CI+    Y C C P    V+      D     C   + +
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQLCPGGPGYQPV 119
             G    R S   S   T   C   +     N C        G   +R +CP GP +   
Sbjct: 661 -DGIN--RYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHH--- 714

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
             P  Y    + ++EC ++   C HG CT     + C C AGW                 
Sbjct: 715 --PSCY----SQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW--VGINCEVDKNECLSN 764

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P   G G C NL   Y C C +G+
Sbjct: 765 PCQNG-GTCDNLVNGYRCTCKKGF 787



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 63/233 (27%), Positives = 89/233 (38%), Gaps = 38/233 (16%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY------ELVSD--------GTAC 47
            G  CT D+DEC S     +G C NTQGSY C CPP +      E + D        G +C
Sbjct: 867  GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSC 926

Query: 48   YD---SRKARCYG-------KVDLRSG-TETCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
             D   +    C         + D+    +E C++    S+      C C  G   G +C+
Sbjct: 927  MDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD-GVHCE 985

Query: 97   ----PCPEPGSEAYRQLCPGGPGYQPVLEPPSYV--VTLADIDECAAHEGLCAHGTCTNT 150
                 C E  S      C  G      L P  +     L +I+EC++H  L   GTC + 
Sbjct: 986  NNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCL-NEGTCVDG 1043

Query: 151  FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G++ C+C  G++               R      G C        CLCP G+
Sbjct: 1044 LGTYRCSCPLGYT---GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 58/215 (26%), Positives = 84/215 (39%), Gaps = 36/215 (16%)

Query: 3   GFNCT-DVDECKSPQS--CQY-GQCINTQGSYTCRCPPNY---ELVSDGTACYD---SRK 52
           G +CT DVDEC    S  C++ G+C+NT G++ C C   Y       D   C+       
Sbjct: 409 GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468

Query: 53  ARCYGKVDLRSGTETCRDSDELSEDGTMAACC-CSVGAAWGNYCDPCPEPGSEAYRQLCP 111
           A C  K+    G  TC     L   G     C   +     N C    +   +  R  C 
Sbjct: 469 ATCLDKI----GGFTC-----LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519

Query: 112 GGPGYQ-PVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXX 169
             PG+  PV +         DID+C++    C +G  C +    + C C  G++      
Sbjct: 520 CPPGFTGPVCQ--------IDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFT----GV 565

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                     PD C  G C++   SY C+C  GY+
Sbjct: 566 LCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM 600



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 62/209 (29%), Positives = 78/209 (37%), Gaps = 28/209 (13%)

Query: 6   CT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVDL 61
           CT DVDEC   P +CQ G  C N  G Y C C   +          D   A C  G   +
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI 354

Query: 62  -RSGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
            R  + +C   +   + G +      C S     G  CD  P  G   Y   CP G    
Sbjct: 355 DRVASFSCMCPE--GKAGLLCHLDDACISNPCHKGALCDTNPLNGQ--YICTCPQGYKGA 410

Query: 118 PVLEPPSYVVTLADIDECA-AHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
              E         D+DECA A+   C H G C NT G+F C C  G++  P         
Sbjct: 411 DCTE---------DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA-GP---RCEMDI 457

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                D C     C +  G + CLC  G+
Sbjct: 458 NECHSDPCQNDATCLDKIGGFTCLCMPGF 486



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 7/83 (8%)

Query: 133 DECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRN 190
           D C +H   CA+G TCT     F C C  G++                P  C  G  C N
Sbjct: 146 DACLSHP--CANGSTCTTVANQFSCKCLTGFT---GQKCETDVNECDIPGHCQHGGTCLN 200

Query: 191 LPGSYVCLCPEGYVAMPNGSQYL 213
           LPGSY C CP+G+      S Y+
Sbjct: 201 LPGSYQCQCPQGFTGQYCDSLYV 223



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 51/215 (23%), Positives = 81/215 (37%), Gaps = 35/215 (16%)

Query: 1   MPGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           MPGF   +C  +++EC+S      GQC++    + C CPP +     G  C         
Sbjct: 483 MPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGPVC--------- 529

Query: 57  GKVDLRSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEAYRQLC 110
            ++D+   + T C +  +  +      C C+ G   G  C    D C P+P    +   C
Sbjct: 530 -QIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFT-GVLCEENIDNCDPDP---CHHGQC 584

Query: 111 PGGPGYQPVLEPPSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXX 168
             G      +  P Y+  +    IDEC +   L   G C +    + C C  G S     
Sbjct: 585 QDGIDSYTCICNPGYMGAICSDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPGTS----G 639

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                       + C  G+C +    Y C+C  G+
Sbjct: 640 VNCEINFDDCASNPCIHGICMDGINRYSCVCSPGF 674



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 58/208 (27%), Positives = 76/208 (36%), Gaps = 24/208 (11%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  D +EC S      G C N    Y C C   ++    G  C       C     L
Sbjct: 751 GINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK----GYNC-QVNIDECASNPCL 805

Query: 62  RSGTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPC-PEPGSEAYRQLCPGGPGYQ-- 117
             G  TC   D++S  G    C     G        PC P P   A   +C   P ++  
Sbjct: 806 NQG--TC--FDDIS--GYTCHCVLPYTGKNCQTVLAPCSPNPCENA--AVCKESPNFESY 857

Query: 118 PVLEPPSY--VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             L  P +       DIDEC + +    HG C NT GS++C C  G+S            
Sbjct: 858 TCLCAPGWQGQRCTIDIDECIS-KPCMNHGLCHNTQGSYMCECPPGFS--GMDCEEDIDD 914

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C +   ++ CLC  G+
Sbjct: 915 CLANPCQNG-GSCMDGVNTFSCLCLPGF 941



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 28/210 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G+NC  ++DEC S      G C +    YTC C   Y     G  C  +  A C    + 
Sbjct: 789 GYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPY----TGKNC-QTVLAPC--SPNP 841

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGY 116
                 C++S           C C+ G  W G  C    D C       +  LC    G 
Sbjct: 842 CENAAVCKESPNFES----YTCLCAPG--WQGQRCTIDIDECISKPCMNH-GLCHNTQGS 894

Query: 117 QPVLEPPSY--VVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP +  +    DID+C A+   C + G+C +   +F C C  G++          
Sbjct: 895 YMCECPPGFSGMDCEEDIDDCLANP--CQNGGSCMDGVNTFSCLCLPGFT--GDKCQTDM 950

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                 P   G G C +   SY C C  G+
Sbjct: 951 NECLSEPCKNG-GTCSDYVNSYTCKCQAGF 979



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 51/211 (24%), Positives = 76/211 (36%), Gaps = 35/211 (16%)

Query: 8    DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
            +++EC S      G C++  G+Y C CP  Y                C   V+L S    
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGY------------TGKNCQTLVNLCS-RSP 1071

Query: 68   CRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSE---------AYRQLCPGGP 114
            C++     +    + C C  G A G YCD     C    S           +  +C    
Sbjct: 1072 CKNKGTCVQKKAESQCLCPSGWA-GAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130

Query: 115  GYQPVLEPPSYVVTLAD--IDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
                   P  Y  +  +  +DECA++   C HG TC++  G + C C  G+         
Sbjct: 1131 NTHYCQCPLGYTGSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQ--GVNCEY 1186

Query: 172  XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                   +P   G G C +L   + C CP G
Sbjct: 1187 EVDECQNQPCQNG-GTCIDLVNHFKCSCPPG 1216



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 57/218 (26%), Positives = 74/218 (33%), Gaps = 29/218 (13%)

Query: 1    MPGFN---C-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            +PGF    C TD++EC S      G C +   SYTC+C   +    DG  C ++    C 
Sbjct: 938  LPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----DGVHC-ENNINECT 992

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC-DPCPEPGSE--AYRQLCPGG 113
                   G  TC D           +C C VG   G++C     E  S        C  G
Sbjct: 993  ESSCFNGG--TCVDGI------NSFSCLCPVGFT-GSFCLHEINECSSHPCLNEGTCVDG 1043

Query: 114  PGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLA----PXX 168
             G      P  Y                C + GTC        C C +GW+ A    P  
Sbjct: 1044 LGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNV 1103

Query: 169  X--XXXXXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                           +C   GVC N   ++ C CP GY
Sbjct: 1104 SCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY 1141



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 52/213 (24%), Positives = 68/213 (31%), Gaps = 25/213 (11%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC T V+ C        G C+  +    C CP  +     G  C D     C      
Sbjct: 1057 GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWA----GAYC-DVPNVSCDIAASR 1111

Query: 62   RSGT--ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP----- 114
            R       C+ S      G    C C +G   G+YC+   E   E     C  G      
Sbjct: 1112 RGVLVEHLCQHSGVCINAGNTHYCQCPLGYT-GSYCE---EQLDECASNPCQHGATCSDF 1167

Query: 115  --GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXX 170
              GY+    P    V    ++DEC      C +G TC +    F C+C  G         
Sbjct: 1168 IGGYRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG--TRGLLCE 1223

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                     P     G C +  G Y C C  G+
Sbjct: 1224 ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF 1256



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 50/209 (23%), Positives = 72/209 (34%), Gaps = 25/209 (11%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G  C   D C S        C      ++C+C   +     G  C ++    C      +
Sbjct: 139 GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKC-ETDVNECDIPGHCQ 193

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PC-PEPGSEAYRQLCPGGPGYQ 117
            G  TC     L+  G+   C C  G   G YCD    PC P P          G   ++
Sbjct: 194 HGG-TC-----LNLPGSYQ-CQCPQGFT-GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 245

Query: 118 PVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               P     T   +ID+C  H   C +G  C +   ++ C C   W+            
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHR--CQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDE 301

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
              +P+ C   G C N  G Y C+C  G+
Sbjct: 302 CLLQPNACQNGGTCANRNGGYGCVCVNGW 330



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 3/56 (5%)

Query: 151 FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           F S+ C C  GW                +P +   G+C N  GSY+C CP G+  M
Sbjct: 854 FESYTCLCAPGWQ--GQRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGFSGM 906



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 37/147 (25%), Positives = 50/147 (34%), Gaps = 12/147 (8%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCI---NTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
            G +C T VD C        G C    N    + CRCPP +      ++C   +  +    
Sbjct: 1298 GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQC 1357

Query: 59   VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCP-GGPGYQ 117
            V   SG      S    E G     C S     G  C P  +P   + +   P  G   +
Sbjct: 1358 VHTASGPRCFCPSPRDCESG-----CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412

Query: 118  PVLEPPSYVVTLADIDECA--AHEGLC 142
                PPS          CA  A +G+C
Sbjct: 1413 LYTAPPSTPPATCLSQYCADKARDGVC 1439


>AK027344-1|BAB55049.1|  741|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14438 fis, clone HEMBB1000317, weakly similar to
           FIBULIN-1, ISOFORM D PRECURSOR. ).
          Length = 741

 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 67/220 (30%), Positives = 82/220 (37%), Gaps = 24/220 (10%)

Query: 3   GFNCTDVDECK-SPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKAR---- 54
           G  C D+DEC     +C  GQ C NT GSY C  RC   +   SDG +C D  + +    
Sbjct: 365 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 424

Query: 55  CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP---CPEP-GSEAYRQLC 110
           C+ +     G+  C         G     C  V     N C P   C    G      LC
Sbjct: 425 CHQRCFNAIGSFHCGCEPGYQLKGRK---CMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 481

Query: 111 PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXX 169
           P G          +   T  DIDEC      C +   C NT GS+ C C  G+       
Sbjct: 482 PNGM-------TKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGR 534

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                      D C    C+N  GSY C+CP GY    NG
Sbjct: 535 PCMDIDECENTDAC-QHECKNTFGSYQCICPPGYQLTHNG 573



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 24/211 (11%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C D DEC +   C +  C N  G+Y C CP    + +DG  C D  +           G 
Sbjct: 328 CADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECAL--------GR 378

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAW-----GNYCDPCPE-PGSEAYRQLCPGGPGYQPV 119
            TC    +         C    G+ +     G  C    E   S    Q C    G    
Sbjct: 379 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 438

Query: 120 LEPPSYVV---TLADIDECAAHEGLCAHGT-CTNTFGSFVC--TCGAGWSLAPXXXXXXX 173
              P Y +      D++EC   + +C     C NT G + C   C  G + A        
Sbjct: 439 GCEPGYQLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDI 496

Query: 174 XXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
                    C    +C N  GSY C+CP GY
Sbjct: 497 DECKDGTHQCRYNQICENTRGSYRCVCPRGY 527



 Score = 59.7 bits (138), Expect = 8e-09
 Identities = 23/47 (48%), Positives = 31/47 (65%), Gaps = 1/47 (2%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G  C D+DEC++  +CQ+ +C NT GSY C CPP Y+L  +G  C D
Sbjct: 533 GRPCMDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQD 578



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 46/169 (27%), Positives = 63/169 (37%), Gaps = 23/169 (13%)

Query: 1   MPGFNCTDVDECKSPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKARCYG 57
           + G  C DV+EC+    C+  Q C NT+G Y C   CP       +GT         C  
Sbjct: 446 LKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT---------CID 495

Query: 58  KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE----PGSEAYRQLCPGG 113
             + + GT  CR +           C C  G        PC +      ++A +  C   
Sbjct: 496 IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECENTDACQHECKNT 555

Query: 114 PGYQPVLEPPSYVV-----TLADIDECAAHEGLCA-HGTCTNTFGSFVC 156
            G    + PP Y +     T  DIDEC      C  +  C N  GS+ C
Sbjct: 556 FGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 604



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 6/84 (7%)

Query: 130 ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCGPGV- 187
           AD DECAA    C+H +C N  G++ C+C  G ++A                  C  G  
Sbjct: 329 ADEDECAAGNP-CSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQD 386

Query: 188 CRNLPGSYVCL--CPEGYVAMPNG 209
           C N  GSY C+  C  G+    +G
Sbjct: 387 CDNTIGSYRCVVRCGSGFRRTSDG 410


>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone RP11-465I11 on chromosome 1. ).
          Length = 5635

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 22/227 (9%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D++EC+  P+ C + QC NT GS+ C CPP   L+ DG +C    +   YG    
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYS 5368

Query: 62   RSGT---ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                      R++ +  +     +   S  + + N             R+ CP G     
Sbjct: 5369 SYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRT-RRTIRKTCPEG----- 5422

Query: 119  VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                 S+  T  DIDEC   +  C H  C NTFGS+ C C  G+ L              
Sbjct: 5423 --SEASHD-TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECL 5477

Query: 179  RPDV-CGPG-VCRNLPGSYVCL---CPEGYVAMPNGSQYLLQNLSTN 220
              +V CGP  +C N+ GSY C+   CP  Y   P  S + L+N   N
Sbjct: 5478 EQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDP-VSGFCLKNCPPN 5523



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 66/221 (29%), Positives = 83/221 (37%), Gaps = 25/221 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKAR---- 54
            G  C D+DEC     +C  GQ C NT GSY C  RC   +   SDG +C D  + +    
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 5201

Query: 55   CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP---CPEP-GSEAYRQLC 110
            C+ +     G+  C         G     C  V     N C P   C    G      LC
Sbjct: 5202 CHQRCFNAIGSFHCGCEPGYQLKGRK---CMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 5258

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW-SLAPXX 168
            P G          +   T  DIDEC      C +   C NT GS+ C C  G+ S     
Sbjct: 5259 PNGM-------TKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGR 5311

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       P  C    C N PGS+ C+CP G   + +G
Sbjct: 5312 PCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDG 5351



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 24/211 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D DEC +   C +  C N  G+Y C CP    + +DG  C D  +           G 
Sbjct: 5105 CADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECAL--------GR 5155

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-----GNYCDPCPE-PGSEAYRQLCPGGPGYQPV 119
             TC    +         C    G+ +     G  C    E   S    Q C    G    
Sbjct: 5156 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 5215

Query: 120  LEPPSYVVT---LADIDECAAHEGLCAHGT-CTNTFGSFVCT--CGAGWSLAPXXXXXXX 173
               P Y +      D++EC   + +C     C NT G + C   C  G + A        
Sbjct: 5216 GCEPGYQLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDI 5273

Query: 174  XXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
                     C    +C N  GSY C+CP GY
Sbjct: 5274 DECKDGTHQCRYNQICENTRGSYRCVCPRGY 5304



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/154 (27%), Positives = 55/154 (35%), Gaps = 19/154 (12%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKARCYG 57
            + G  C DV+EC+    C+  Q C NT+G Y C   CP       +GT         C  
Sbjct: 5223 LKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT---------CID 5272

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPG 112
              + + GT  CR +           C C  G        PC      E   +     C  
Sbjct: 5273 IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSN 5332

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT 146
             PG    + PP   + L D   CA  E L  +GT
Sbjct: 5333 TPGSFKCICPPGQHL-LGDGKSCAGLERLPNYGT 5365


>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-268N14 on chromosome 1. ).
          Length = 5635

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 22/227 (9%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D++EC+  P+ C + QC NT GS+ C CPP   L+ DG +C    +   YG    
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYS 5368

Query: 62   RSGT---ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                      R++ +  +     +   S  + + N             R+ CP G     
Sbjct: 5369 SYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRT-RRTIRKTCPEG----- 5422

Query: 119  VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                 S+  T  DIDEC   +  C H  C NTFGS+ C C  G+ L              
Sbjct: 5423 --SEASHD-TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECL 5477

Query: 179  RPDV-CGPG-VCRNLPGSYVCL---CPEGYVAMPNGSQYLLQNLSTN 220
              +V CGP  +C N+ GSY C+   CP  Y   P  S + L+N   N
Sbjct: 5478 EQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDP-VSGFCLKNCPPN 5523



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 66/221 (29%), Positives = 83/221 (37%), Gaps = 25/221 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKAR---- 54
            G  C D+DEC     +C  GQ C NT GSY C  RC   +   SDG +C D  + +    
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 5201

Query: 55   CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP---CPEP-GSEAYRQLC 110
            C+ +     G+  C         G     C  V     N C P   C    G      LC
Sbjct: 5202 CHQRCFNAIGSFHCGCEPGYQLKGRK---CMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 5258

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW-SLAPXX 168
            P G          +   T  DIDEC      C +   C NT GS+ C C  G+ S     
Sbjct: 5259 PNGM-------TKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGR 5311

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       P  C    C N PGS+ C+CP G   + +G
Sbjct: 5312 PCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDG 5351



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 24/211 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D DEC +   C +  C N  G+Y C CP    + +DG  C D  +           G 
Sbjct: 5105 CADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECAL--------GR 5155

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-----GNYCDPCPE-PGSEAYRQLCPGGPGYQPV 119
             TC    +         C    G+ +     G  C    E   S    Q C    G    
Sbjct: 5156 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 5215

Query: 120  LEPPSYVVT---LADIDECAAHEGLCAHGT-CTNTFGSFVCT--CGAGWSLAPXXXXXXX 173
               P Y +      D++EC   + +C     C NT G + C   C  G + A        
Sbjct: 5216 GCEPGYQLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDI 5273

Query: 174  XXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
                     C    +C N  GSY C+CP GY
Sbjct: 5274 DECKDGTHQCRYNQICENTRGSYRCVCPRGY 5304



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/154 (27%), Positives = 55/154 (35%), Gaps = 19/154 (12%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKARCYG 57
            + G  C DV+EC+    C+  Q C NT+G Y C   CP       +GT         C  
Sbjct: 5223 LKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT---------CID 5272

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPG 112
              + + GT  CR +           C C  G        PC      E   +     C  
Sbjct: 5273 IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSN 5332

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT 146
             PG    + PP   + L D   CA  E L  +GT
Sbjct: 5333 TPGSFKCICPPGQHL-LGDGKSCAGLERLPNYGT 5365


>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-77J13 on chromosome 1. ).
          Length = 5635

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 22/227 (9%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D++EC+  P+ C + QC NT GS+ C CPP   L+ DG +C    +   YG    
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYS 5368

Query: 62   RSGT---ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                      R++ +  +     +   S  + + N             R+ CP G     
Sbjct: 5369 SYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRT-RRTIRKTCPEG----- 5422

Query: 119  VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                 S+  T  DIDEC   +  C H  C NTFGS+ C C  G+ L              
Sbjct: 5423 --SEASHD-TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECL 5477

Query: 179  RPDV-CGPG-VCRNLPGSYVCL---CPEGYVAMPNGSQYLLQNLSTN 220
              +V CGP  +C N+ GSY C+   CP  Y   P  S + L+N   N
Sbjct: 5478 EQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDP-VSGFCLKNCPPN 5523



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 66/221 (29%), Positives = 83/221 (37%), Gaps = 25/221 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKAR---- 54
            G  C D+DEC     +C  GQ C NT GSY C  RC   +   SDG +C D  + +    
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 5201

Query: 55   CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP---CPEP-GSEAYRQLC 110
            C+ +     G+  C         G     C  V     N C P   C    G      LC
Sbjct: 5202 CHQRCFNAIGSFHCGCEPGYQLKGRK---CMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 5258

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW-SLAPXX 168
            P G          +   T  DIDEC      C +   C NT GS+ C C  G+ S     
Sbjct: 5259 PNGM-------TKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGR 5311

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       P  C    C N PGS+ C+CP G   + +G
Sbjct: 5312 PCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDG 5351



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 24/211 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D DEC +   C +  C N  G+Y C CP    + +DG  C D  +           G 
Sbjct: 5105 CADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECAL--------GR 5155

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-----GNYCDPCPE-PGSEAYRQLCPGGPGYQPV 119
             TC    +         C    G+ +     G  C    E   S    Q C    G    
Sbjct: 5156 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 5215

Query: 120  LEPPSYVVT---LADIDECAAHEGLCAHGT-CTNTFGSFVCT--CGAGWSLAPXXXXXXX 173
               P Y +      D++EC   + +C     C NT G + C   C  G + A        
Sbjct: 5216 GCEPGYQLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDI 5273

Query: 174  XXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
                     C    +C N  GSY C+CP GY
Sbjct: 5274 DECKDGTHQCRYNQICENTRGSYRCVCPRGY 5304



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/154 (27%), Positives = 55/154 (35%), Gaps = 19/154 (12%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKARCYG 57
            + G  C DV+EC+    C+  Q C NT+G Y C   CP       +GT         C  
Sbjct: 5223 LKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT---------CID 5272

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPG 112
              + + GT  CR +           C C  G        PC      E   +     C  
Sbjct: 5273 IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSN 5332

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT 146
             PG    + PP   + L D   CA  E L  +GT
Sbjct: 5333 TPGSFKCICPPGQHL-LGDGKSCAGLERLPNYGT 5365


>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-164L12 on chromosome 1. ).
          Length = 5635

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 22/227 (9%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D++EC+  P+ C + QC NT GS+ C CPP   L+ DG +C    +   YG    
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYS 5368

Query: 62   RSGT---ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                      R++ +  +     +   S  + + N             R+ CP G     
Sbjct: 5369 SYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRT-RRTIRKTCPEG----- 5422

Query: 119  VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                 S+  T  DIDEC   +  C H  C NTFGS+ C C  G+ L              
Sbjct: 5423 --SEASHD-TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECL 5477

Query: 179  RPDV-CGPG-VCRNLPGSYVCL---CPEGYVAMPNGSQYLLQNLSTN 220
              +V CGP  +C N+ GSY C+   CP  Y   P  S + L+N   N
Sbjct: 5478 EQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDP-VSGFCLKNCPPN 5523



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 66/221 (29%), Positives = 83/221 (37%), Gaps = 25/221 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKAR---- 54
            G  C D+DEC     +C  GQ C NT GSY C  RC   +   SDG +C D  + +    
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 5201

Query: 55   CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP---CPEP-GSEAYRQLC 110
            C+ +     G+  C         G     C  V     N C P   C    G      LC
Sbjct: 5202 CHQRCFNAIGSFHCGCEPGYQLKGRK---CMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 5258

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW-SLAPXX 168
            P G          +   T  DIDEC      C +   C NT GS+ C C  G+ S     
Sbjct: 5259 PNGM-------TKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGR 5311

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       P  C    C N PGS+ C+CP G   + +G
Sbjct: 5312 PCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDG 5351



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 24/211 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D DEC +   C +  C N  G+Y C CP    + +DG  C D  +           G 
Sbjct: 5105 CADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECAL--------GR 5155

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-----GNYCDPCPE-PGSEAYRQLCPGGPGYQPV 119
             TC    +         C    G+ +     G  C    E   S    Q C    G    
Sbjct: 5156 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 5215

Query: 120  LEPPSYVVT---LADIDECAAHEGLCAHGT-CTNTFGSFVCT--CGAGWSLAPXXXXXXX 173
               P Y +      D++EC   + +C     C NT G + C   C  G + A        
Sbjct: 5216 GCEPGYQLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDI 5273

Query: 174  XXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
                     C    +C N  GSY C+CP GY
Sbjct: 5274 DECKDGTHQCRYNQICENTRGSYRCVCPRGY 5304



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/154 (27%), Positives = 55/154 (35%), Gaps = 19/154 (12%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKARCYG 57
            + G  C DV+EC+    C+  Q C NT+G Y C   CP       +GT         C  
Sbjct: 5223 LKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT---------CID 5272

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPG 112
              + + GT  CR +           C C  G        PC      E   +     C  
Sbjct: 5273 IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSN 5332

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT 146
             PG    + PP   + L D   CA  E L  +GT
Sbjct: 5333 TPGSFKCICPPGQHL-LGDGKSCAGLERLPNYGT 5365


>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-174L6 on chromosome 1. ).
          Length = 5635

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 22/227 (9%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D++EC+  P+ C + QC NT GS+ C CPP   L+ DG +C    +   YG    
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYS 5368

Query: 62   RSGT---ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                      R++ +  +     +   S  + + N             R+ CP G     
Sbjct: 5369 SYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRT-RRTIRKTCPEG----- 5422

Query: 119  VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                 S+  T  DIDEC   +  C H  C NTFGS+ C C  G+ L              
Sbjct: 5423 --SEASHD-TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECL 5477

Query: 179  RPDV-CGPG-VCRNLPGSYVCL---CPEGYVAMPNGSQYLLQNLSTN 220
              +V CGP  +C N+ GSY C+   CP  Y   P  S + L+N   N
Sbjct: 5478 EQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDP-VSGFCLKNCPPN 5523



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 66/221 (29%), Positives = 83/221 (37%), Gaps = 25/221 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKAR---- 54
            G  C D+DEC     +C  GQ C NT GSY C  RC   +   SDG +C D  + +    
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 5201

Query: 55   CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP---CPEP-GSEAYRQLC 110
            C+ +     G+  C         G     C  V     N C P   C    G      LC
Sbjct: 5202 CHQRCFNAIGSFHCGCEPGYQLKGRK---CMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 5258

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW-SLAPXX 168
            P G          +   T  DIDEC      C +   C NT GS+ C C  G+ S     
Sbjct: 5259 PNGM-------TKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGR 5311

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       P  C    C N PGS+ C+CP G   + +G
Sbjct: 5312 PCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDG 5351



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 24/211 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D DEC +   C +  C N  G+Y C CP    + +DG  C D  +           G 
Sbjct: 5105 CADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECAL--------GR 5155

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-----GNYCDPCPE-PGSEAYRQLCPGGPGYQPV 119
             TC    +         C    G+ +     G  C    E   S    Q C    G    
Sbjct: 5156 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 5215

Query: 120  LEPPSYVVT---LADIDECAAHEGLCAHGT-CTNTFGSFVCT--CGAGWSLAPXXXXXXX 173
               P Y +      D++EC   + +C     C NT G + C   C  G + A        
Sbjct: 5216 GCEPGYQLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDI 5273

Query: 174  XXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
                     C    +C N  GSY C+CP GY
Sbjct: 5274 DECKDGTHQCRYNQICENTRGSYRCVCPRGY 5304



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/154 (27%), Positives = 55/154 (35%), Gaps = 19/154 (12%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKARCYG 57
            + G  C DV+EC+    C+  Q C NT+G Y C   CP       +GT         C  
Sbjct: 5223 LKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT---------CID 5272

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPG 112
              + + GT  CR +           C C  G        PC      E   +     C  
Sbjct: 5273 IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSN 5332

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT 146
             PG    + PP   + L D   CA  E L  +GT
Sbjct: 5333 TPGSFKCICPPGQHL-LGDGKSCAGLERLPNYGT 5365


>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-153O3 on chromosome 1. ).
          Length = 5635

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 22/227 (9%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D++EC+  P+ C + QC NT GS+ C CPP   L+ DG +C    +   YG    
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYS 5368

Query: 62   RSGT---ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                      R++ +  +     +   S  + + N             R+ CP G     
Sbjct: 5369 SYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRT-RRTIRKTCPEG----- 5422

Query: 119  VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                 S+  T  DIDEC   +  C H  C NTFGS+ C C  G+ L              
Sbjct: 5423 --SEASHD-TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECL 5477

Query: 179  RPDV-CGPG-VCRNLPGSYVCL---CPEGYVAMPNGSQYLLQNLSTN 220
              +V CGP  +C N+ GSY C+   CP  Y   P  S + L+N   N
Sbjct: 5478 EQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDP-VSGFCLKNCPPN 5523



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 66/221 (29%), Positives = 83/221 (37%), Gaps = 25/221 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKAR---- 54
            G  C D+DEC     +C  GQ C NT GSY C  RC   +   SDG +C D  + +    
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 5201

Query: 55   CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP---CPEP-GSEAYRQLC 110
            C+ +     G+  C         G     C  V     N C P   C    G      LC
Sbjct: 5202 CHQRCFNAIGSFHCGCEPGYQLKGRK---CMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 5258

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW-SLAPXX 168
            P G          +   T  DIDEC      C +   C NT GS+ C C  G+ S     
Sbjct: 5259 PNGM-------TKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGR 5311

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       P  C    C N PGS+ C+CP G   + +G
Sbjct: 5312 PCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDG 5351



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 24/211 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D DEC +   C +  C N  G+Y C CP    + +DG  C D  +           G 
Sbjct: 5105 CADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECAL--------GR 5155

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-----GNYCDPCPE-PGSEAYRQLCPGGPGYQPV 119
             TC    +         C    G+ +     G  C    E   S    Q C    G    
Sbjct: 5156 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 5215

Query: 120  LEPPSYVVT---LADIDECAAHEGLCAHGT-CTNTFGSFVCT--CGAGWSLAPXXXXXXX 173
               P Y +      D++EC   + +C     C NT G + C   C  G + A        
Sbjct: 5216 GCEPGYQLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDI 5273

Query: 174  XXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
                     C    +C N  GSY C+CP GY
Sbjct: 5274 DECKDGTHQCRYNQICENTRGSYRCVCPRGY 5304



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/154 (27%), Positives = 55/154 (35%), Gaps = 19/154 (12%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKARCYG 57
            + G  C DV+EC+    C+  Q C NT+G Y C   CP       +GT         C  
Sbjct: 5223 LKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT---------CID 5272

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPG 112
              + + GT  CR +           C C  G        PC      E   +     C  
Sbjct: 5273 IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSN 5332

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT 146
             PG    + PP   + L D   CA  E L  +GT
Sbjct: 5333 TPGSFKCICPPGQHL-LGDGKSCAGLERLPNYGT 5365


>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
          Length = 5635

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 22/227 (9%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D++EC+  P+ C + QC NT GS+ C CPP   L+ DG +C    +   YG    
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYS 5368

Query: 62   RSGT---ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                      R++ +  +     +   S  + + N             R+ CP G     
Sbjct: 5369 SYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRT-RRTIRKTCPEG----- 5422

Query: 119  VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                 S+  T  DIDEC   +  C H  C NTFGS+ C C  G+ L              
Sbjct: 5423 --SEASHD-TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECL 5477

Query: 179  RPDV-CGPG-VCRNLPGSYVCL---CPEGYVAMPNGSQYLLQNLSTN 220
              +V CGP  +C N+ GSY C+   CP  Y   P  S + L+N   N
Sbjct: 5478 EQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDP-VSGFCLKNCPPN 5523



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 66/221 (29%), Positives = 83/221 (37%), Gaps = 25/221 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKAR---- 54
            G  C D+DEC     +C  GQ C NT GSY C  RC   +   SDG +C D  + +    
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 5201

Query: 55   CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP---CPEP-GSEAYRQLC 110
            C+ +     G+  C         G     C  V     N C P   C    G      LC
Sbjct: 5202 CHQRCFNAIGSFHCGCEPGYQLKGRK---CMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 5258

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW-SLAPXX 168
            P G          +   T  DIDEC      C +   C NT GS+ C C  G+ S     
Sbjct: 5259 PNGM-------TKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGR 5311

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       P  C    C N PGS+ C+CP G   + +G
Sbjct: 5312 PCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDG 5351



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 24/211 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D DEC +   C +  C N  G+Y C CP    + +DG  C D  +           G 
Sbjct: 5105 CADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECAL--------GR 5155

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-----GNYCDPCPE-PGSEAYRQLCPGGPGYQPV 119
             TC    +         C    G+ +     G  C    E   S    Q C    G    
Sbjct: 5156 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 5215

Query: 120  LEPPSYVVT---LADIDECAAHEGLCAHGT-CTNTFGSFVCT--CGAGWSLAPXXXXXXX 173
               P Y +      D++EC   + +C     C NT G + C   C  G + A        
Sbjct: 5216 GCEPGYQLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDI 5273

Query: 174  XXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
                     C    +C N  GSY C+CP GY
Sbjct: 5274 DECKDGTHQCRYNQICENTRGSYRCVCPRGY 5304



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/154 (27%), Positives = 55/154 (35%), Gaps = 19/154 (12%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKARCYG 57
            + G  C DV+EC+    C+  Q C NT+G Y C   CP       +GT         C  
Sbjct: 5223 LKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT---------CID 5272

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPG 112
              + + GT  CR +           C C  G        PC      E   +     C  
Sbjct: 5273 IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSN 5332

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT 146
             PG    + PP   + L D   CA  E L  +GT
Sbjct: 5333 TPGSFKCICPPGQHL-LGDGKSCAGLERLPNYGT 5365


>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
          Length = 5635

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 22/227 (9%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D++EC+  P+ C + QC NT GS+ C CPP   L+ DG +C    +   YG    
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYS 5368

Query: 62   RSGT---ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                      R++ +  +     +   S  + + N             R+ CP G     
Sbjct: 5369 SYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRT-RRTIRKTCPEG----- 5422

Query: 119  VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                 S+  T  DIDEC   +  C H  C NTFGS+ C C  G+ L              
Sbjct: 5423 --SEASHD-TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECL 5477

Query: 179  RPDV-CGPG-VCRNLPGSYVCL---CPEGYVAMPNGSQYLLQNLSTN 220
              +V CGP  +C N+ GSY C+   CP  Y   P  S + L+N   N
Sbjct: 5478 EQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDP-VSGFCLKNCPPN 5523



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 66/221 (29%), Positives = 83/221 (37%), Gaps = 25/221 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKAR---- 54
            G  C D+DEC     +C  GQ C NT GSY C  RC   +   SDG +C D  + +    
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 5201

Query: 55   CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP---CPEP-GSEAYRQLC 110
            C+ +     G+  C         G     C  V     N C P   C    G      LC
Sbjct: 5202 CHQRCFNAIGSFHCGCEPGYQLKGRK---CMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 5258

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW-SLAPXX 168
            P G          +   T  DIDEC      C +   C NT GS+ C C  G+ S     
Sbjct: 5259 PNGM-------TKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGR 5311

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       P  C    C N PGS+ C+CP G   + +G
Sbjct: 5312 PCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDG 5351



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 24/211 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D DEC +   C +  C N  G+Y C CP    + +DG  C D  +           G 
Sbjct: 5105 CADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECAL--------GR 5155

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-----GNYCDPCPE-PGSEAYRQLCPGGPGYQPV 119
             TC    +         C    G+ +     G  C    E   S    Q C    G    
Sbjct: 5156 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 5215

Query: 120  LEPPSYVVT---LADIDECAAHEGLCAHGT-CTNTFGSFVCT--CGAGWSLAPXXXXXXX 173
               P Y +      D++EC   + +C     C NT G + C   C  G + A        
Sbjct: 5216 GCEPGYQLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDI 5273

Query: 174  XXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
                     C    +C N  GSY C+CP GY
Sbjct: 5274 DECKDGTHQCRYNQICENTRGSYRCVCPRGY 5304



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/154 (27%), Positives = 55/154 (35%), Gaps = 19/154 (12%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKARCYG 57
            + G  C DV+EC+    C+  Q C NT+G Y C   CP       +GT         C  
Sbjct: 5223 LKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT---------CID 5272

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPG 112
              + + GT  CR +           C C  G        PC      E   +     C  
Sbjct: 5273 IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSN 5332

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT 146
             PG    + PP   + L D   CA  E L  +GT
Sbjct: 5333 TPGSFKCICPPGQHL-LGDGKSCAGLERLPNYGT 5365


>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
          Length = 2673

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 22/227 (9%)

Query: 3    GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G  C D++EC+  P+ C + QC NT GS+ C CPP   L+ DG +C    +   YG    
Sbjct: 2348 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYS 2406

Query: 62   RSGT---ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                      R++ +  +     +   S  + + N             R+ CP G     
Sbjct: 2407 SYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRT-RRTIRKTCPEG----- 2460

Query: 119  VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                 S+  T  DIDEC   +  C H  C NTFGS+ C C  G+ L              
Sbjct: 2461 --SEASHD-TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECL 2515

Query: 179  RPDV-CGPG-VCRNLPGSYVCL---CPEGYVAMPNGSQYLLQNLSTN 220
              +V CGP  +C N+ GSY C+   CP  Y   P  S + L+N   N
Sbjct: 2516 EQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDP-VSGFCLKNCPPN 2561



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 66/221 (29%), Positives = 83/221 (37%), Gaps = 25/221 (11%)

Query: 3    GFNCTDVDECK-SPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKAR---- 54
            G  C D+DEC     +C  GQ C NT GSY C  RC   +   SDG +C D  + +    
Sbjct: 2180 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 2239

Query: 55   CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP---CPEP-GSEAYRQLC 110
            C+ +     G+  C         G     C  V     N C P   C    G      LC
Sbjct: 2240 CHQRCFNAIGSFHCGCEPGYQLKGRK---CMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 2296

Query: 111  PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW-SLAPXX 168
            P G          +   T  DIDEC      C +   C NT GS+ C C  G+ S     
Sbjct: 2297 PNGM-------TKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGR 2349

Query: 169  XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                       P  C    C N PGS+ C+CP G   + +G
Sbjct: 2350 PCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDG 2389



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 24/211 (11%)

Query: 6    CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
            C D DEC +   C +  C N  G+Y C CP    + +DG  C D  +           G 
Sbjct: 2143 CADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECAL--------GR 2193

Query: 66   ETCRDSDELSEDGTMAACCCSVGAAW-----GNYCDPCPE-PGSEAYRQLCPGGPGYQPV 119
             TC    +         C    G+ +     G  C    E   S    Q C    G    
Sbjct: 2194 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 2253

Query: 120  LEPPSYVVT---LADIDECAAHEGLCAHGT-CTNTFGSFVCT--CGAGWSLAPXXXXXXX 173
               P Y +      D++EC   + +C     C NT G + C   C  G + A        
Sbjct: 2254 GCEPGYQLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDI 2311

Query: 174  XXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
                     C    +C N  GSY C+CP GY
Sbjct: 2312 DECKDGTHQCRYNQICENTRGSYRCVCPRGY 2342



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/154 (27%), Positives = 55/154 (35%), Gaps = 19/154 (12%)

Query: 1    MPGFNCTDVDECKSPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKARCYG 57
            + G  C DV+EC+    C+  Q C NT+G Y C   CP       +GT         C  
Sbjct: 2261 LKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT---------CID 2310

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPG 112
              + + GT  CR +           C C  G        PC      E   +     C  
Sbjct: 2311 IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSN 2370

Query: 113  GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT 146
             PG    + PP   + L D   CA  E L  +GT
Sbjct: 2371 TPGSFKCICPPGQHL-LGDGKSCAGLERLPNYGT 2403


>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
          Length = 2321

 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 66/211 (31%), Positives = 86/211 (40%), Gaps = 30/211 (14%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G +C +DVDEC+  + C++G  C+NT GS+ C+CP  Y     G  C ++    C     
Sbjct: 152 GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY----TGPLC-ENPAVPC-APSP 205

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYR-QLCPGGPG 115
            R+G  TCR S +L+ D     C C  G   G  C    D C  PG        C  G  
Sbjct: 206 CRNG-GTCRQSGDLTYD-----CACLPGFE-GQNCEVNVDDC--PGHRCLNGGTCVDGVN 256

Query: 116 YQPVLEPPSYV--VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                 PP +       D+DEC      C + GTC NT G   C C  GW+         
Sbjct: 257 TYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWT----GESCS 312

Query: 173 XXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                    VC  G  C +   S+ C CP G
Sbjct: 313 QNIDDCATAVCFHGATCHDRVASFYCACPMG 343



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 59/197 (29%), Positives = 76/197 (38%), Gaps = 28/197 (14%)

Query: 16  QSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDS-RKARCYGKVDLRSGTETCRDSDEL 74
           + C +G C +  G + C C P +     G  C  S  +  C         ++ CR     
Sbjct: 702 EPCSHGICYDAPGGFRCVCEPGWS----GPRCSQSLARDACE--------SQPCRAGGTC 749

Query: 75  SEDGTMAACCCSVGAAWGNYCD---PC-PEPGSEAYRQLCPGGPGYQPVLEPPSYVV--- 127
           S DG    C C  G   G  C+   PC P P     R  C   PG  PV   P       
Sbjct: 750 SSDGMGFHCTCPPGVQ-GRQCELLSPCTPNPCEHGGR--CESAPGQLPVCSCPQGWQGPR 806

Query: 128 TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GPG 186
              D+DECA       HG CTN  GSF CTC  G++  P             P+ C   G
Sbjct: 807 CQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT-GPSCDQDINDCD---PNPCLNGG 862

Query: 187 VCRNLPGSYVCLCPEGY 203
            C++  GS+ C C  G+
Sbjct: 863 SCQDGVGSFSCSCLPGF 879



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 54/205 (26%), Positives = 77/205 (37%), Gaps = 21/205 (10%)

Query: 6   CT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           CT DVDEC+  P +C  G  C NT G ++C C   +   S      D   A C+      
Sbjct: 271 CTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCH 330

Query: 63  SGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
               +   +  + + G +      C S        CD  P  G    R +C   PG+   
Sbjct: 331 DRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNG----RAICTCPPGF--- 383

Query: 120 LEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
               +      D+DEC+     C H G C NT GSF+C CG G++  P            
Sbjct: 384 ----TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT-GPRCETDVNECLSG 438

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
                    C +  G + C+C  G+
Sbjct: 439 --PCRNQATCLDRIGQFTCICMAGF 461



 Score = 59.7 bits (138), Expect = 8e-09
 Identities = 57/215 (26%), Positives = 88/215 (40%), Gaps = 29/215 (13%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           +VD+C SP  C +G+C++   S++C C P Y     GT        RC  +VD    ++ 
Sbjct: 545 NVDDC-SPDPCHHGRCVDGIASFSCACAPGY----TGT--------RCESQVD-ECRSQP 590

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQPVLEPPS 124
           CR   +  +      C C  G    N     D C    +     +C  G      +  P 
Sbjct: 591 CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDC--ASNPCTFGVCRDGINRYDCVCQPG 648

Query: 125 YVVTL--ADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
           +   L   +I+ECA+    C   G+C +    F C C  G SL P              +
Sbjct: 649 FTGPLCNVEINECASSP--CGEGGSCVDGENGFRCLCPPG-SLPPLCLPPSHPCAH---E 702

Query: 182 VCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
            C  G+C + PG + C+C  G+ + P  SQ L ++
Sbjct: 703 PCSHGICYDAPGGFRCVCEPGW-SGPRCSQSLARD 736



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 62/216 (28%), Positives = 90/216 (41%), Gaps = 30/216 (13%)

Query: 7    TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY---GKVDLR 62
            T VD C S Q CQ G +C+ T G+Y C CPP +     G  C D R   C     ++ +R
Sbjct: 999  TLVDWC-SRQPCQNGGRCVQT-GAY-CLCPPGWS----GRLC-DIRSLPCREAAAQIGVR 1050

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQP 118
               + C+   +  ++ +   C C  G   G++C    DPC     + +   C G  G   
Sbjct: 1051 L-EQLCQAGGQCVDEDSSHYCVCPEGRT-GSHCEQEVDPCLAQPCQ-HGGTCRGYMGGYM 1107

Query: 119  VLEPPSYVVTLA--DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P Y       D+DECA+    C HG +C +    ++C+C  G +L           
Sbjct: 1108 CECLPGYNGDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCPPG-TLGVLCEINEDDC 1164

Query: 176  XXXRPDVCGP-----GVCRNLPGSYVCLCPEGYVAM 206
                P   GP     G C +L G + C CP GY  +
Sbjct: 1165 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGL 1200



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 54/210 (25%), Positives = 74/210 (35%), Gaps = 30/210 (14%)

Query: 3   GFNCTDVDECKSPQSCQYG-QCINTQGSY-TCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C  +  C +P  C++G +C +  G    C CP  ++              RC   VD
Sbjct: 766 GRQCELLSPC-TPNPCEHGGRCESAPGQLPVCSCPQGWQ------------GPRCQQDVD 812

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP----CPEPGSEAYRQLCPGGPGY 116
             +G   C      +      +C C  G   G  CD     C +P        C  G G 
Sbjct: 813 ECAGPAPCGPHGICTNLAGSFSCTCH-GGYTGPSCDQDINDC-DPNPCLNGGSCQDGVGS 870

Query: 117 QPVLEPPSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
                 P +       D+DEC ++   C  GTCT+   SF CTC  G+            
Sbjct: 871 FSCSCLPGFAGPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYG----GFHCEQD 924

Query: 175 XXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                P  C   G C +   S+ CLC  GY
Sbjct: 925 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGY 954



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 51/213 (23%), Positives = 78/213 (36%), Gaps = 31/213 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           M GF  T    D+DEC+S      G C +    ++C CP  +     G+ C         
Sbjct: 458 MAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF----SGSTC--------- 504

Query: 57  GKVDLRSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS--EAYRQLCPGG 113
            ++D+     T CR+  +  +      C C+ G   G  CD   +  S    +   C  G
Sbjct: 505 -QLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE-GTLCDRNVDDCSPDPCHHGRCVDG 562

Query: 114 PGYQPVLEPPSYVVTLAD--IDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXX 170
                    P Y  T  +  +DEC +    C H G C +    ++C C +G         
Sbjct: 563 IASFSCACAPGYTGTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSG----TTGVN 616

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                     + C  GVCR+    Y C+C  G+
Sbjct: 617 CEVNIDDCASNPCTFGVCRDGINRYDCVCQPGF 649



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 50/209 (23%), Positives = 70/209 (33%), Gaps = 24/209 (11%)

Query: 3   GFNCTDVDECKSPQSCQYGQC-INTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C+  D C S       +C +   G + C CPP Y+    G +C           VD 
Sbjct: 114 GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ----GRSCRSD--------VDE 161

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PC-PEPGSEAYRQLCPGGPGY 116
               E CR             C C  G   G  C+    PC P P          G   Y
Sbjct: 162 CRVGEPCRHGGTCLNTPGSFRCQCPAGYT-GPLCENPAVPCAPSPCRNGGTCRQSGDLTY 220

Query: 117 QPVLEPPSYVVTL-ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P         ++D+C  H  L   GTC +   ++ C C   W+            
Sbjct: 221 DCACLPGFEGQNCEVNVDDCPGHRCLNG-GTCVDGVNTYNCQCPPEWT--GQFCTEDVDE 277

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
              +P+ C   G C N  G + C+C  G+
Sbjct: 278 CQLQPNACHNGGTCFNTLGGHSCVCVNGW 306



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 26/181 (14%)

Query: 32  CRCPPNY--ELVSDGTACYD---SRKARCYGKVDLRSGTETCRDSDEL-SEDGTMAACCC 85
           C CPP +  E       C+    + +  C   V   +   +CR        D ++   C 
Sbjct: 65  CLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCL 124

Query: 86  SVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG 145
           S   A G  C   P+      R LC   PGYQ            +D+DEC   E  C HG
Sbjct: 125 SSPCAHGARCSVGPDG-----RFLCSCPPGYQGRS-------CRSDVDECRVGEP-CRHG 171

Query: 146 -TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GPGVCRNLPG-SYVCLCPEG 202
            TC NT GSF C C AG++  P             P  C   G CR     +Y C C  G
Sbjct: 172 GTCLNTPGSFRCQCPAGYT-GPLCENPAVPCA---PSPCRNGGTCRQSGDLTYDCACLPG 227

Query: 203 Y 203
           +
Sbjct: 228 F 228



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 61/220 (27%), Positives = 80/220 (36%), Gaps = 38/220 (17%)

Query: 1    MPGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            +PGF    C  DVDEC S   C  G C +   S+TC CPP Y     G  C +     C 
Sbjct: 876  LPGFAGPRCARDVDECLS-NPCGPGTCTDHVASFTCTCPPGY----GGFHC-EQDLPDCS 929

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPG 112
                   G  TC D           +C C  G   G +C    DPC       +  +C  
Sbjct: 930  PSSCFNGG--TCVDG------VNSFSCLCRPGYT-GAHCQHEADPCLSRPC-LHGGVCSA 979

Query: 113  G-PGYQ-PVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS------ 163
              PG++   LE  +       +D C+     C + G C  T G++ C C  GWS      
Sbjct: 980  AHPGFRCTCLESFTGPQCQTLVDWCSRQP--CQNGGRCVQT-GAY-CLCPPGWSGRLCDI 1035

Query: 164  -LAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
               P                   G C +   S+ C+CPEG
Sbjct: 1036 RSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG 1075



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 20/36 (55%), Positives = 22/36 (61%), Gaps = 3/36 (8%)

Query: 3    GFNCTD-VDECKSPQSCQYG-QCINTQGSYTCRCPP 36
            G NC D VDEC S Q CQ+G  CI+    Y C CPP
Sbjct: 1116 GDNCEDDVDECAS-QPCQHGGSCIDLVARYLCSCPP 1150



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 49/216 (22%), Positives = 75/216 (34%), Gaps = 30/216 (13%)

Query: 1   MPGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF   NC  +VD+C   +    G C++   +Y C+CPP +     G  C +     C 
Sbjct: 225 LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEW----TGQFCTED-VDECQ 279

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGPG 115
            + +      TC +        T+    C     W    + C +   +    +C  G   
Sbjct: 280 LQPNACHNGGTCFN--------TLGGHSCVCVNGWTG--ESCSQNIDDCATAVCFHGATC 329

Query: 116 YQPVLE-----PPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
           +  V       P      L  +D+            C TN   G  +CTC  G++     
Sbjct: 330 HDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD 389

Query: 169 XXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGY 203
                      P  C   G C N  GS++C C  GY
Sbjct: 390 QDVDECSIGANP--CEHLGRCVNTQGSFLCQCGRGY 423



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 50/177 (28%), Positives = 67/177 (37%), Gaps = 31/177 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G +C  +VD C + Q CQ+G  C    G Y C C P Y    +G  C D         VD
Sbjct: 1078 GSHCEQEVDPCLA-QPCQHGGTCRGYMGGYMCECLPGY----NGDNCEDD--------VD 1124

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEA-----YRQLC 110
                ++ C+      +      C C  G   G  C    D C P P  ++     +   C
Sbjct: 1125 -ECASQPCQHGGSCIDLVARYLCSCPPGTL-GVLCEINEDDCGPGPPLDSGPRCLHNGTC 1182

Query: 111  PGGPGYQPVLEPPSY--VVTLADIDECAAHEGLCAH--GTCTNTFGSFVCTCGAGWS 163
                G      PP Y  +   ADI+EC +     AH      +  G F C C AG+S
Sbjct: 1183 VDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFS 1239



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 23/95 (24%), Positives = 32/95 (33%), Gaps = 7/95 (7%)

Query: 15   PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK------VDLRSGTE-T 67
            P+    G C++  G + C CPP Y  +       + R   C+         D   G    
Sbjct: 1174 PRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCL 1233

Query: 68   CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPG 102
            C          T+ + C S     G  C P P PG
Sbjct: 1234 CHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPG 1268


>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
          Length = 2321

 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 66/211 (31%), Positives = 86/211 (40%), Gaps = 30/211 (14%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G +C +DVDEC+  + C++G  C+NT GS+ C+CP  Y     G  C ++    C     
Sbjct: 152 GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY----TGPLC-ENPAVPC-APSP 205

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYR-QLCPGGPG 115
            R+G  TCR S +L+ D     C C  G   G  C    D C  PG        C  G  
Sbjct: 206 CRNG-GTCRQSGDLTYD-----CACLPGFE-GQNCEVNVDDC--PGHRCLNGGTCVDGVN 256

Query: 116 YQPVLEPPSYV--VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                 PP +       D+DEC      C + GTC NT G   C C  GW+         
Sbjct: 257 TYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWT----GESCS 312

Query: 173 XXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                    VC  G  C +   S+ C CP G
Sbjct: 313 QNIDDCATAVCFHGATCHDRVASFYCACPMG 343



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 59/197 (29%), Positives = 76/197 (38%), Gaps = 28/197 (14%)

Query: 16  QSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDS-RKARCYGKVDLRSGTETCRDSDEL 74
           + C +G C +  G + C C P +     G  C  S  +  C         ++ CR     
Sbjct: 702 EPCSHGICYDAPGGFRCVCEPGWS----GPRCSQSLARDACE--------SQPCRAGGTC 749

Query: 75  SEDGTMAACCCSVGAAWGNYCD---PC-PEPGSEAYRQLCPGGPGYQPVLEPPSYVV--- 127
           S DG    C C  G   G  C+   PC P P     R  C   PG  PV   P       
Sbjct: 750 SSDGMGFHCTCPPGVQ-GRQCELLSPCTPNPCEHGGR--CESAPGQLPVCSCPQGWQGPR 806

Query: 128 TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GPG 186
              D+DECA       HG CTN  GSF CTC  G++  P             P+ C   G
Sbjct: 807 CQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT-GPSCDQDINDCD---PNPCLNGG 862

Query: 187 VCRNLPGSYVCLCPEGY 203
            C++  GS+ C C  G+
Sbjct: 863 SCQDGVGSFSCSCLPGF 879



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 54/205 (26%), Positives = 77/205 (37%), Gaps = 21/205 (10%)

Query: 6   CT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           CT DVDEC+  P +C  G  C NT G ++C C   +   S      D   A C+      
Sbjct: 271 CTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCH 330

Query: 63  SGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
               +   +  + + G +      C S        CD  P  G    R +C   PG+   
Sbjct: 331 DRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNG----RAICTCPPGF--- 383

Query: 120 LEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
               +      D+DEC+     C H G C NT GSF+C CG G++  P            
Sbjct: 384 ----TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT-GPRCETDVNECLSG 438

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
                    C +  G + C+C  G+
Sbjct: 439 --PCRNQATCLDRIGQFTCICMAGF 461



 Score = 59.7 bits (138), Expect = 8e-09
 Identities = 57/215 (26%), Positives = 88/215 (40%), Gaps = 29/215 (13%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           +VD+C SP  C +G+C++   S++C C P Y     GT        RC  +VD    ++ 
Sbjct: 545 NVDDC-SPDPCHHGRCVDGIASFSCACAPGY----TGT--------RCESQVD-ECRSQP 590

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQPVLEPPS 124
           CR   +  +      C C  G    N     D C    +     +C  G      +  P 
Sbjct: 591 CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDC--ASNPCTFGVCRDGINRYDCVCQPG 648

Query: 125 YVVTL--ADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
           +   L   +I+ECA+    C   G+C +    F C C  G SL P              +
Sbjct: 649 FTGPLCNVEINECASSP--CGEGGSCVDGENGFRCLCPPG-SLPPLCLPPSHPCAH---E 702

Query: 182 VCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
            C  G+C + PG + C+C  G+ + P  SQ L ++
Sbjct: 703 PCSHGICYDAPGGFRCVCEPGW-SGPRCSQSLARD 736



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 62/216 (28%), Positives = 90/216 (41%), Gaps = 30/216 (13%)

Query: 7    TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY---GKVDLR 62
            T VD C S Q CQ G +C+ T G+Y C CPP +     G  C D R   C     ++ +R
Sbjct: 999  TLVDWC-SRQPCQNGGRCVQT-GAY-CLCPPGWS----GRLC-DIRSLPCREAAAQIGVR 1050

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQP 118
               + C+   +  ++ +   C C  G   G++C    DPC     + +   C G  G   
Sbjct: 1051 L-EQLCQAGGQCVDEDSSHYCVCPEGRT-GSHCEQEVDPCLAQPCQ-HGGTCRGYMGGYM 1107

Query: 119  VLEPPSYVVTLA--DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P Y       D+DECA+    C HG +C +    ++C+C  G +L           
Sbjct: 1108 CECLPGYNGDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCPPG-TLGVLCEINEDDC 1164

Query: 176  XXXRPDVCGP-----GVCRNLPGSYVCLCPEGYVAM 206
                P   GP     G C +L G + C CP GY  +
Sbjct: 1165 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGL 1200



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 54/210 (25%), Positives = 74/210 (35%), Gaps = 30/210 (14%)

Query: 3   GFNCTDVDECKSPQSCQYG-QCINTQGSY-TCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C  +  C +P  C++G +C +  G    C CP  ++              RC   VD
Sbjct: 766 GRQCELLSPC-TPNPCEHGGRCESAPGQLPVCSCPQGWQ------------GPRCQQDVD 812

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP----CPEPGSEAYRQLCPGGPGY 116
             +G   C      +      +C C  G   G  CD     C +P        C  G G 
Sbjct: 813 ECAGPAPCGPHGICTNLAGSFSCTCH-GGYTGPSCDQDINDC-DPNPCLNGGSCQDGVGS 870

Query: 117 QPVLEPPSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
                 P +       D+DEC ++   C  GTCT+   SF CTC  G+            
Sbjct: 871 FSCSCLPGFAGPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYG----GFHCEQD 924

Query: 175 XXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                P  C   G C +   S+ CLC  GY
Sbjct: 925 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGY 954



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 51/213 (23%), Positives = 78/213 (36%), Gaps = 31/213 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           M GF  T    D+DEC+S      G C +    ++C CP  +     G+ C         
Sbjct: 458 MAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF----SGSTC--------- 504

Query: 57  GKVDLRSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS--EAYRQLCPGG 113
            ++D+     T CR+  +  +      C C+ G   G  CD   +  S    +   C  G
Sbjct: 505 -QLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE-GTLCDRNVDDCSPDPCHHGRCVDG 562

Query: 114 PGYQPVLEPPSYVVTLAD--IDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXX 170
                    P Y  T  +  +DEC +    C H G C +    ++C C +G         
Sbjct: 563 IASFSCACAPGYTGTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSG----TTGVN 616

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                     + C  GVCR+    Y C+C  G+
Sbjct: 617 CEVNIDDCASNPCTFGVCRDGINRYDCVCQPGF 649



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 50/209 (23%), Positives = 70/209 (33%), Gaps = 24/209 (11%)

Query: 3   GFNCTDVDECKSPQSCQYGQC-INTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C+  D C S       +C +   G + C CPP Y+    G +C           VD 
Sbjct: 114 GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ----GRSCRSD--------VDE 161

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PC-PEPGSEAYRQLCPGGPGY 116
               E CR             C C  G   G  C+    PC P P          G   Y
Sbjct: 162 CRVGEPCRHGGTCLNTPGSFRCQCPAGYT-GPLCENPAVPCAPSPCRNGGTCRQSGDLTY 220

Query: 117 QPVLEPPSYVVTL-ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P         ++D+C  H  L   GTC +   ++ C C   W+            
Sbjct: 221 DCACLPGFEGQNCEVNVDDCPGHRCLNG-GTCVDGVNTYNCQCPPEWT--GQFCTEDVDE 277

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
              +P+ C   G C N  G + C+C  G+
Sbjct: 278 CQLQPNACHNGGTCFNTLGGHSCVCVNGW 306



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 26/181 (14%)

Query: 32  CRCPPNY--ELVSDGTACYD---SRKARCYGKVDLRSGTETCRDSDEL-SEDGTMAACCC 85
           C CPP +  E       C+    + +  C   V   +   +CR        D ++   C 
Sbjct: 65  CLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCL 124

Query: 86  SVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG 145
           S   A G  C   P+      R LC   PGYQ            +D+DEC   E  C HG
Sbjct: 125 SSPCAHGARCSVGPDG-----RFLCSCPPGYQGRS-------CRSDVDECRVGEP-CRHG 171

Query: 146 -TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GPGVCRNLPG-SYVCLCPEG 202
            TC NT GSF C C AG++  P             P  C   G CR     +Y C C  G
Sbjct: 172 GTCLNTPGSFRCQCPAGYT-GPLCENPAVPCA---PSPCRNGGTCRQSGDLTYDCACLPG 227

Query: 203 Y 203
           +
Sbjct: 228 F 228



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 61/220 (27%), Positives = 80/220 (36%), Gaps = 38/220 (17%)

Query: 1    MPGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            +PGF    C  DVDEC S   C  G C +   S+TC CPP Y     G  C +     C 
Sbjct: 876  LPGFAGPRCARDVDECLS-NPCGPGTCTDHVASFTCTCPPGY----GGFHC-EQDLPDCS 929

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPG 112
                   G  TC D           +C C  G   G +C    DPC       +  +C  
Sbjct: 930  PSSCFNGG--TCVDG------VNSFSCLCRPGYT-GAHCQHEADPCLSRPC-LHGGVCSA 979

Query: 113  G-PGYQ-PVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS------ 163
              PG++   LE  +       +D C+     C + G C  T G++ C C  GWS      
Sbjct: 980  AHPGFRCTCLESFTGPQCQTLVDWCSRQP--CQNGGRCVQT-GAY-CLCPPGWSGRLCDI 1035

Query: 164  -LAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
               P                   G C +   S+ C+CPEG
Sbjct: 1036 RSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG 1075



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 20/36 (55%), Positives = 22/36 (61%), Gaps = 3/36 (8%)

Query: 3    GFNCTD-VDECKSPQSCQYG-QCINTQGSYTCRCPP 36
            G NC D VDEC S Q CQ+G  CI+    Y C CPP
Sbjct: 1116 GDNCEDDVDECAS-QPCQHGGSCIDLVARYLCSCPP 1150



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 49/216 (22%), Positives = 75/216 (34%), Gaps = 30/216 (13%)

Query: 1   MPGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF   NC  +VD+C   +    G C++   +Y C+CPP +     G  C +     C 
Sbjct: 225 LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEW----TGQFCTED-VDECQ 279

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGPG 115
            + +      TC +        T+    C     W    + C +   +    +C  G   
Sbjct: 280 LQPNACHNGGTCFN--------TLGGHSCVCVNGWTG--ESCSQNIDDCATAVCFHGATC 329

Query: 116 YQPVLE-----PPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
           +  V       P      L  +D+            C TN   G  +CTC  G++     
Sbjct: 330 HDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD 389

Query: 169 XXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGY 203
                      P  C   G C N  GS++C C  GY
Sbjct: 390 QDVDECSIGANP--CEHLGRCVNTQGSFLCQCGRGY 423



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 50/177 (28%), Positives = 67/177 (37%), Gaps = 31/177 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G +C  +VD C + Q CQ+G  C    G Y C C P Y    +G  C D         VD
Sbjct: 1078 GSHCEQEVDPCLA-QPCQHGGTCRGYMGGYMCECLPGY----NGDNCEDD--------VD 1124

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEA-----YRQLC 110
                ++ C+      +      C C  G   G  C    D C P P  ++     +   C
Sbjct: 1125 -ECASQPCQHGGSCIDLVARYLCSCPPGTL-GVLCEINEDDCGPGPPLDSGPRCLHNGTC 1182

Query: 111  PGGPGYQPVLEPPSY--VVTLADIDECAAHEGLCAH--GTCTNTFGSFVCTCGAGWS 163
                G      PP Y  +   ADI+EC +     AH      +  G F C C AG+S
Sbjct: 1183 VDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFS 1239



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 23/95 (24%), Positives = 32/95 (33%), Gaps = 7/95 (7%)

Query: 15   PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK------VDLRSGTE-T 67
            P+    G C++  G + C CPP Y  +       + R   C+         D   G    
Sbjct: 1174 PRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCL 1233

Query: 68   CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPG 102
            C          T+ + C S     G  C P P PG
Sbjct: 1234 CHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPG 1268


>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
          Length = 2281

 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 66/211 (31%), Positives = 86/211 (40%), Gaps = 30/211 (14%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G +C +DVDEC+  + C++G  C+NT GS+ C+CP  Y     G  C ++    C     
Sbjct: 112 GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY----TGPLC-ENPAVPC-APSP 165

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYR-QLCPGGPG 115
            R+G  TCR S +L+ D     C C  G   G  C    D C  PG        C  G  
Sbjct: 166 CRNG-GTCRQSGDLTYD-----CACLPGFE-GQNCEVNVDDC--PGHRCLNGGTCVDGVN 216

Query: 116 YQPVLEPPSYV--VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                 PP +       D+DEC      C + GTC NT G   C C  GW+         
Sbjct: 217 TYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWT----GESCS 272

Query: 173 XXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                    VC  G  C +   S+ C CP G
Sbjct: 273 QNIDDCATAVCFHGATCHDRVASFYCACPMG 303



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 59/197 (29%), Positives = 76/197 (38%), Gaps = 28/197 (14%)

Query: 16  QSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDS-RKARCYGKVDLRSGTETCRDSDEL 74
           + C +G C +  G + C C P +     G  C  S  +  C         ++ CR     
Sbjct: 662 EPCSHGICYDAPGGFRCVCEPGWS----GPRCSQSLARDACE--------SQPCRAGGTC 709

Query: 75  SEDGTMAACCCSVGAAWGNYCD---PC-PEPGSEAYRQLCPGGPGYQPVLEPPSYVV--- 127
           S DG    C C  G   G  C+   PC P P     R  C   PG  PV   P       
Sbjct: 710 SSDGMGFHCTCPPGVQ-GRQCELLSPCTPNPCEHGGR--CESAPGQLPVCSCPQGWQGPR 766

Query: 128 TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GPG 186
              D+DECA       HG CTN  GSF CTC  G++  P             P+ C   G
Sbjct: 767 CQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT-GPSCDQDINDCD---PNPCLNGG 822

Query: 187 VCRNLPGSYVCLCPEGY 203
            C++  GS+ C C  G+
Sbjct: 823 SCQDGVGSFSCSCLPGF 839



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 54/205 (26%), Positives = 77/205 (37%), Gaps = 21/205 (10%)

Query: 6   CT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           CT DVDEC+  P +C  G  C NT G ++C C   +   S      D   A C+      
Sbjct: 231 CTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCH 290

Query: 63  SGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
               +   +  + + G +      C S        CD  P  G    R +C   PG+   
Sbjct: 291 DRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNG----RAICTCPPGF--- 343

Query: 120 LEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
               +      D+DEC+     C H G C NT GSF+C CG G++  P            
Sbjct: 344 ----TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT-GPRCETDVNECLSG 398

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
                    C +  G + C+C  G+
Sbjct: 399 --PCRNQATCLDRIGQFTCICMAGF 421



 Score = 59.7 bits (138), Expect = 8e-09
 Identities = 57/215 (26%), Positives = 88/215 (40%), Gaps = 29/215 (13%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           +VD+C SP  C +G+C++   S++C C P Y     GT        RC  +VD    ++ 
Sbjct: 505 NVDDC-SPDPCHHGRCVDGIASFSCACAPGY----TGT--------RCESQVD-ECRSQP 550

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQPVLEPPS 124
           CR   +  +      C C  G    N     D C    +     +C  G      +  P 
Sbjct: 551 CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDC--ASNPCTFGVCRDGINRYDCVCQPG 608

Query: 125 YVVTL--ADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
           +   L   +I+ECA+    C   G+C +    F C C  G SL P              +
Sbjct: 609 FTGPLCNVEINECASSP--CGEGGSCVDGENGFRCLCPPG-SLPPLCLPPSHPCAH---E 662

Query: 182 VCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
            C  G+C + PG + C+C  G+ + P  SQ L ++
Sbjct: 663 PCSHGICYDAPGGFRCVCEPGW-SGPRCSQSLARD 696



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 62/216 (28%), Positives = 90/216 (41%), Gaps = 30/216 (13%)

Query: 7    TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY---GKVDLR 62
            T VD C S Q CQ G +C+ T G+Y C CPP +     G  C D R   C     ++ +R
Sbjct: 959  TLVDWC-SRQPCQNGGRCVQT-GAY-CLCPPGWS----GRLC-DIRSLPCREAAAQIGVR 1010

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQP 118
               + C+   +  ++ +   C C  G   G++C    DPC     + +   C G  G   
Sbjct: 1011 L-EQLCQAGGQCVDEDSSHYCVCPEGRT-GSHCEQEVDPCLAQPCQ-HGGTCRGYMGGYM 1067

Query: 119  VLEPPSYVVTLA--DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P Y       D+DECA+    C HG +C +    ++C+C  G +L           
Sbjct: 1068 CECLPGYNGDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCPPG-TLGVLCEINEDDC 1124

Query: 176  XXXRPDVCGP-----GVCRNLPGSYVCLCPEGYVAM 206
                P   GP     G C +L G + C CP GY  +
Sbjct: 1125 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGL 1160



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 54/210 (25%), Positives = 74/210 (35%), Gaps = 30/210 (14%)

Query: 3   GFNCTDVDECKSPQSCQYG-QCINTQGSY-TCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C  +  C +P  C++G +C +  G    C CP  ++              RC   VD
Sbjct: 726 GRQCELLSPC-TPNPCEHGGRCESAPGQLPVCSCPQGWQ------------GPRCQQDVD 772

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDP----CPEPGSEAYRQLCPGGPGY 116
             +G   C      +      +C C  G   G  CD     C +P        C  G G 
Sbjct: 773 ECAGPAPCGPHGICTNLAGSFSCTCH-GGYTGPSCDQDINDC-DPNPCLNGGSCQDGVGS 830

Query: 117 QPVLEPPSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
                 P +       D+DEC ++   C  GTCT+   SF CTC  G+            
Sbjct: 831 FSCSCLPGFAGPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYG----GFHCEQD 884

Query: 175 XXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                P  C   G C +   S+ CLC  GY
Sbjct: 885 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGY 914



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 51/213 (23%), Positives = 78/213 (36%), Gaps = 31/213 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           M GF  T    D+DEC+S      G C +    ++C CP  +     G+ C         
Sbjct: 418 MAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF----SGSTC--------- 464

Query: 57  GKVDLRSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS--EAYRQLCPGG 113
            ++D+     T CR+  +  +      C C+ G   G  CD   +  S    +   C  G
Sbjct: 465 -QLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE-GTLCDRNVDDCSPDPCHHGRCVDG 522

Query: 114 PGYQPVLEPPSYVVTLAD--IDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXX 170
                    P Y  T  +  +DEC +    C H G C +    ++C C +G         
Sbjct: 523 IASFSCACAPGYTGTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSG----TTGVN 576

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                     + C  GVCR+    Y C+C  G+
Sbjct: 577 CEVNIDDCASNPCTFGVCRDGINRYDCVCQPGF 609



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 50/209 (23%), Positives = 70/209 (33%), Gaps = 24/209 (11%)

Query: 3   GFNCTDVDECKSPQSCQYGQC-INTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C+  D C S       +C +   G + C CPP Y+    G +C           VD 
Sbjct: 74  GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ----GRSCRSD--------VDE 121

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PC-PEPGSEAYRQLCPGGPGY 116
               E CR             C C  G   G  C+    PC P P          G   Y
Sbjct: 122 CRVGEPCRHGGTCLNTPGSFRCQCPAGYT-GPLCENPAVPCAPSPCRNGGTCRQSGDLTY 180

Query: 117 QPVLEPPSYVVTL-ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P         ++D+C  H  L   GTC +   ++ C C   W+            
Sbjct: 181 DCACLPGFEGQNCEVNVDDCPGHRCLNG-GTCVDGVNTYNCQCPPEWT--GQFCTEDVDE 237

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
              +P+ C   G C N  G + C+C  G+
Sbjct: 238 CQLQPNACHNGGTCFNTLGGHSCVCVNGW 266



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 26/181 (14%)

Query: 32  CRCPPNY--ELVSDGTACYD---SRKARCYGKVDLRSGTETCRDSDEL-SEDGTMAACCC 85
           C CPP +  E       C+    + +  C   V   +   +CR        D ++   C 
Sbjct: 25  CLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCL 84

Query: 86  SVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG 145
           S   A G  C   P+      R LC   PGYQ            +D+DEC   E  C HG
Sbjct: 85  SSPCAHGARCSVGPDG-----RFLCSCPPGYQGRS-------CRSDVDECRVGEP-CRHG 131

Query: 146 -TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GPGVCRNLPG-SYVCLCPEG 202
            TC NT GSF C C AG++  P             P  C   G CR     +Y C C  G
Sbjct: 132 GTCLNTPGSFRCQCPAGYT-GPLCENPAVPCA---PSPCRNGGTCRQSGDLTYDCACLPG 187

Query: 203 Y 203
           +
Sbjct: 188 F 188



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 61/220 (27%), Positives = 80/220 (36%), Gaps = 38/220 (17%)

Query: 1    MPGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            +PGF    C  DVDEC S   C  G C +   S+TC CPP Y     G  C +     C 
Sbjct: 836  LPGFAGPRCARDVDECLS-NPCGPGTCTDHVASFTCTCPPGY----GGFHC-EQDLPDCS 889

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPG 112
                   G  TC D           +C C  G   G +C    DPC       +  +C  
Sbjct: 890  PSSCFNGG--TCVDG------VNSFSCLCRPGYT-GAHCQHEADPCLSRPC-LHGGVCSA 939

Query: 113  G-PGYQ-PVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS------ 163
              PG++   LE  +       +D C+     C + G C  T G++ C C  GWS      
Sbjct: 940  AHPGFRCTCLESFTGPQCQTLVDWCSRQP--CQNGGRCVQT-GAY-CLCPPGWSGRLCDI 995

Query: 164  -LAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
               P                   G C +   S+ C+CPEG
Sbjct: 996  RSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG 1035



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 20/36 (55%), Positives = 22/36 (61%), Gaps = 3/36 (8%)

Query: 3    GFNCTD-VDECKSPQSCQYG-QCINTQGSYTCRCPP 36
            G NC D VDEC S Q CQ+G  CI+    Y C CPP
Sbjct: 1076 GDNCEDDVDECAS-QPCQHGGSCIDLVARYLCSCPP 1110



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 49/216 (22%), Positives = 75/216 (34%), Gaps = 30/216 (13%)

Query: 1   MPGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF   NC  +VD+C   +    G C++   +Y C+CPP +     G  C +     C 
Sbjct: 185 LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEW----TGQFCTED-VDECQ 239

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGPG 115
            + +      TC +        T+    C     W    + C +   +    +C  G   
Sbjct: 240 LQPNACHNGGTCFN--------TLGGHSCVCVNGWTG--ESCSQNIDDCATAVCFHGATC 289

Query: 116 YQPVLE-----PPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
           +  V       P      L  +D+            C TN   G  +CTC  G++     
Sbjct: 290 HDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD 349

Query: 169 XXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGY 203
                      P  C   G C N  GS++C C  GY
Sbjct: 350 QDVDECSIGANP--CEHLGRCVNTQGSFLCQCGRGY 383



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 50/177 (28%), Positives = 67/177 (37%), Gaps = 31/177 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G +C  +VD C + Q CQ+G  C    G Y C C P Y    +G  C D         VD
Sbjct: 1038 GSHCEQEVDPCLA-QPCQHGGTCRGYMGGYMCECLPGY----NGDNCEDD--------VD 1084

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEA-----YRQLC 110
                ++ C+      +      C C  G   G  C    D C P P  ++     +   C
Sbjct: 1085 -ECASQPCQHGGSCIDLVARYLCSCPPGTL-GVLCEINEDDCGPGPPLDSGPRCLHNGTC 1142

Query: 111  PGGPGYQPVLEPPSY--VVTLADIDECAAHEGLCAH--GTCTNTFGSFVCTCGAGWS 163
                G      PP Y  +   ADI+EC +     AH      +  G F C C AG+S
Sbjct: 1143 VDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFS 1199



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 23/95 (24%), Positives = 32/95 (33%), Gaps = 7/95 (7%)

Query: 15   PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK------VDLRSGTE-T 67
            P+    G C++  G + C CPP Y  +       + R   C+         D   G    
Sbjct: 1134 PRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCL 1193

Query: 68   CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPG 102
            C          T+ + C S     G  C P P PG
Sbjct: 1194 CHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPG 1228


>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
           protein.
          Length = 1289

 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 66/211 (31%), Positives = 86/211 (40%), Gaps = 30/211 (14%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G +C +DVDEC+  + C++G  C+NT GS+ C+CP  Y     G  C ++    C     
Sbjct: 155 GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY----TGPLC-ENPAVPC-APSP 208

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYR-QLCPGGPG 115
            R+G  TCR S +L+ D     C C  G   G  C    D C  PG        C  G  
Sbjct: 209 CRNG-GTCRQSGDLTYD-----CACLPGFE-GQNCEVNVDDC--PGHRCLNGGTCVDGVN 259

Query: 116 YQPVLEPPSYV--VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                 PP +       D+DEC      C + GTC NT G   C C  GW+         
Sbjct: 260 TYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWT----GESCS 315

Query: 173 XXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                    VC  G  C +   S+ C CP G
Sbjct: 316 QNIDDCATAVCFHGATCHDRVASFYCACPMG 346



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 54/205 (26%), Positives = 77/205 (37%), Gaps = 21/205 (10%)

Query: 6   CT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           CT DVDEC+  P +C  G  C NT G ++C C   +   S      D   A C+      
Sbjct: 274 CTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCH 333

Query: 63  SGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
               +   +  + + G +      C S        CD  P  G    R +C   PG+   
Sbjct: 334 DRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNG----RAICTCPPGF--- 386

Query: 120 LEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
               +      D+DEC+     C H G C NT GSF+C CG G++  P            
Sbjct: 387 ----TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT-GPRCETDVNECLSG 441

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
                    C +  G + C+C  G+
Sbjct: 442 --PCRNQATCLDRIGQFTCICMAGF 464



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 55/193 (28%), Positives = 72/193 (37%), Gaps = 35/193 (18%)

Query: 16  QSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDS-RKARCYGKVDLRSGTETCRDSDEL 74
           + C +G C +  G + C C P +     G  C  S  +  C         ++ CR     
Sbjct: 705 EPCSHGICYDAPGGFRCVCEPGWS----GPRCSQSLARDACE--------SQPCRAGGTC 752

Query: 75  SEDGTMAACCCSVGAAWGNYCD---PC-PEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLA 130
           S DG    C C  G   G  C+   PC P P     R  C   PG  PV   P       
Sbjct: 753 SSDGMGFHCTCPPGVQ-GRQCELLSPCTPNPCEHGGR--CESAPGQLPVCSCPQ-----G 804

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
             D C    G    G+C +  GSF C+C  G++  P              + CGPG C +
Sbjct: 805 WQDPCL--NG----GSCQDGVGSFSCSCLPGFA-GPRCARDVDECLS---NPCGPGTCTD 854

Query: 191 LPGSYVCLCPEGY 203
              S+ C CP GY
Sbjct: 855 HVASFTCTCPPGY 867



 Score = 59.7 bits (138), Expect = 8e-09
 Identities = 57/215 (26%), Positives = 88/215 (40%), Gaps = 29/215 (13%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           +VD+C SP  C +G+C++   S++C C P Y     GT        RC  +VD    ++ 
Sbjct: 548 NVDDC-SPDPCHHGRCVDGIASFSCACAPGY----TGT--------RCESQVD-ECRSQP 593

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQPVLEPPS 124
           CR   +  +      C C  G    N     D C    +     +C  G      +  P 
Sbjct: 594 CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDC--ASNPCTFGVCRDGINRYDCVCQPG 651

Query: 125 YVVTL--ADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
           +   L   +I+ECA+    C   G+C +    F C C  G SL P              +
Sbjct: 652 FTGPLCNVEINECASSP--CGEGGSCVDGENGFRCLCPPG-SLPPLCLPPSHPCAH---E 705

Query: 182 VCGPGVCRNLPGSYVCLCPEGYVAMPNGSQYLLQN 216
            C  G+C + PG + C+C  G+ + P  SQ L ++
Sbjct: 706 PCSHGICYDAPGGFRCVCEPGW-SGPRCSQSLARD 739



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 62/216 (28%), Positives = 90/216 (41%), Gaps = 30/216 (13%)

Query: 7    TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY---GKVDLR 62
            T VD C S Q CQ G +C+ T G+Y C CPP +     G  C D R   C     ++ +R
Sbjct: 950  TLVDWC-SRQPCQNGGRCVQT-GAY-CLCPPGWS----GRLC-DIRSLPCREAAAQIGVR 1001

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQP 118
               + C+   +  ++ +   C C  G   G++C    DPC     + +   C G  G   
Sbjct: 1002 L-EQLCQAGGQCVDEDSSHYCVCPEGRT-GSHCEQEVDPCLAQPCQ-HGGTCRGYMGGYM 1058

Query: 119  VLEPPSYVVTLA--DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P Y       D+DECA+    C HG +C +    ++C+C  G +L           
Sbjct: 1059 CECLPGYNGDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCPPG-TLGVLCEINEDDC 1115

Query: 176  XXXRPDVCGP-----GVCRNLPGSYVCLCPEGYVAM 206
                P   GP     G C +L G + C CP GY  +
Sbjct: 1116 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGL 1151



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 56/198 (28%), Positives = 72/198 (36%), Gaps = 35/198 (17%)

Query: 10  DECKSPQSCQYGQCINTQG-SYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETC 68
           D C+S Q C+ G   ++ G  + C CPP  +    G  C     + C        G   C
Sbjct: 739 DACES-QPCRAGGTCSSDGMGFHCTCPPGVQ----GRQC--ELLSPCTPNPCEHGGR--C 789

Query: 69  RDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVT 128
                 S  G +  C C  G  W    DPC   GS      C  G G       P +   
Sbjct: 790 E-----SAPGQLPVCSCPQG--WQ---DPCLNGGS------CQDGVGSFSCSCLPGFAGP 833

Query: 129 LA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GP 185
               D+DEC ++   C  GTCT+   SF CTC  G+                 P  C   
Sbjct: 834 RCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYG----GFHCEQDLPDCSPSSCFNG 887

Query: 186 GVCRNLPGSYVCLCPEGY 203
           G C +   S+ CLC  GY
Sbjct: 888 GTCVDGVNSFSCLCRPGY 905



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 51/213 (23%), Positives = 78/213 (36%), Gaps = 31/213 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           M GF  T    D+DEC+S      G C +    ++C CP  +     G+ C         
Sbjct: 461 MAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF----SGSTC--------- 507

Query: 57  GKVDLRSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS--EAYRQLCPGG 113
            ++D+     T CR+  +  +      C C+ G   G  CD   +  S    +   C  G
Sbjct: 508 -QLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE-GTLCDRNVDDCSPDPCHHGRCVDG 565

Query: 114 PGYQPVLEPPSYVVTLAD--IDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXX 170
                    P Y  T  +  +DEC +    C H G C +    ++C C +G         
Sbjct: 566 IASFSCACAPGYTGTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSG----TTGVN 619

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                     + C  GVCR+    Y C+C  G+
Sbjct: 620 CEVNIDDCASNPCTFGVCRDGINRYDCVCQPGF 652



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 50/209 (23%), Positives = 70/209 (33%), Gaps = 24/209 (11%)

Query: 3   GFNCTDVDECKSPQSCQYGQC-INTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C+  D C S       +C +   G + C CPP Y+    G +C           VD 
Sbjct: 117 GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ----GRSCRSD--------VDE 164

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PC-PEPGSEAYRQLCPGGPGY 116
               E CR             C C  G   G  C+    PC P P          G   Y
Sbjct: 165 CRVGEPCRHGGTCLNTPGSFRCQCPAGYT-GPLCENPAVPCAPSPCRNGGTCRQSGDLTY 223

Query: 117 QPVLEPPSYVVTL-ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P         ++D+C  H  L   GTC +   ++ C C   W+            
Sbjct: 224 DCACLPGFEGQNCEVNVDDCPGHRCLNG-GTCVDGVNTYNCQCPPEWT--GQFCTEDVDE 280

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
              +P+ C   G C N  G + C+C  G+
Sbjct: 281 CQLQPNACHNGGTCFNTLGGHSCVCVNGW 309



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 26/181 (14%)

Query: 32  CRCPPNY--ELVSDGTACYD---SRKARCYGKVDLRSGTETCRDSDEL-SEDGTMAACCC 85
           C CPP +  E       C+    + +  C   V   +   +CR        D ++   C 
Sbjct: 68  CLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCL 127

Query: 86  SVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG 145
           S   A G  C   P+      R LC   PGYQ            +D+DEC   E  C HG
Sbjct: 128 SSPCAHGARCSVGPDG-----RFLCSCPPGYQGRS-------CRSDVDECRVGEP-CRHG 174

Query: 146 -TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GPGVCRNLPG-SYVCLCPEG 202
            TC NT GSF C C AG++  P             P  C   G CR     +Y C C  G
Sbjct: 175 GTCLNTPGSFRCQCPAGYT-GPLCENPAVPCA---PSPCRNGGTCRQSGDLTYDCACLPG 230

Query: 203 Y 203
           +
Sbjct: 231 F 231



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 57/210 (27%), Positives = 74/210 (35%), Gaps = 22/210 (10%)

Query: 3    GFNCT-DVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            GF+C  D+ +C SP SC   G C++   S++C C P Y     G  C       C  +  
Sbjct: 869  GFHCEQDLPDC-SPSSCFNGGTCVDGVNSFSCLCRPGY----TGAHCQHEADP-CLSRPC 922

Query: 61   LRSGT-ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPG----SEAYRQLCPGGPG 115
            L  G           +   +     C     W +   PC   G    + AY  LCP  PG
Sbjct: 923  LHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSR-QPCQNGGRCVQTGAY-CLCP--PG 978

Query: 116  YQPVL-EPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
            +   L +  S     A        E LC A G C +   S  C C  G            
Sbjct: 979  WSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG--RTGSHCEQEV 1036

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                 +P   G G CR   G Y+C C  GY
Sbjct: 1037 DPCLAQPCQHG-GTCRGYMGGYMCECLPGY 1065



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 20/36 (55%), Positives = 22/36 (61%), Gaps = 3/36 (8%)

Query: 3    GFNCTD-VDECKSPQSCQYG-QCINTQGSYTCRCPP 36
            G NC D VDEC S Q CQ+G  CI+    Y C CPP
Sbjct: 1067 GDNCEDDVDECAS-QPCQHGGSCIDLVARYLCSCPP 1101



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 49/216 (22%), Positives = 75/216 (34%), Gaps = 30/216 (13%)

Query: 1   MPGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF   NC  +VD+C   +    G C++   +Y C+CPP +     G  C +     C 
Sbjct: 228 LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEW----TGQFCTED-VDECQ 282

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGPG 115
            + +      TC +        T+    C     W    + C +   +    +C  G   
Sbjct: 283 LQPNACHNGGTCFN--------TLGGHSCVCVNGWTG--ESCSQNIDDCATAVCFHGATC 332

Query: 116 YQPVLE-----PPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
           +  V       P      L  +D+            C TN   G  +CTC  G++     
Sbjct: 333 HDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD 392

Query: 169 XXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGY 203
                      P  C   G C N  GS++C C  GY
Sbjct: 393 QDVDECSIGANP--CEHLGRCVNTQGSFLCQCGRGY 426



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 23/95 (24%), Positives = 32/95 (33%), Gaps = 7/95 (7%)

Query: 15   PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK------VDLRSGTE-T 67
            P+    G C++  G + C CPP Y  +       + R   C+         D   G    
Sbjct: 1125 PRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCL 1184

Query: 68   CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPG 102
            C          T+ + C S     G  C P P PG
Sbjct: 1185 CHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPG 1219


>U76764-1|AAB36682.1|  835|Homo sapiens CD97 protein.
          Length = 835

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 64/214 (29%), Positives = 85/214 (39%), Gaps = 42/214 (19%)

Query: 2   PGFNCTDVDECKSPQ--SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           P   C D++EC +P   SC ++  C NT+GSY C C P YE VS GT  + +        
Sbjct: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS-GTKTFKNESEN---- 112

Query: 59  VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                   TC+D DE  ++  +   C S G             GS      C   PG++ 
Sbjct: 113 --------TCQDVDECQQNPRL---CKSYGTCVNTL-------GSYT----CQCLPGFKF 150

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
           + E P       D++EC + +  C   T C N  GS+ C C  GW   P           
Sbjct: 151 IPEDPK---VCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 207

Query: 178 XRPDVCGPG--------VCRNLPGSYVCLCPEGY 203
              D C  G        VC N  GSY C C  G+
Sbjct: 208 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 58/192 (30%), Positives = 83/192 (43%), Gaps = 25/192 (13%)

Query: 26  TQGSYTCR--CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAAC 83
           TQ S  C   CP N   V+  TAC  +     + ++ + + TETC   D+++E  T +  
Sbjct: 20  TQDSRGCARWCPQNSSCVN-ATACRCNPGFSSFSEI-ITTPTETC---DDINECATPSKV 74

Query: 84  CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV----TLADIDECAAHE 139
            C      G + D     GS  Y  +C   PGY+PV    ++      T  D+DEC  + 
Sbjct: 75  SC------GKFSDCWNTEGS--YDCVC--SPGYEPVSGTKTFKNESENTCQDVDECQQNP 124

Query: 140 GLC-AHGTCTNTFGSFVCTCGAGWSLAPX--XXXXXXXXXXXRPDVCGPGV-CRNLPGSY 195
            LC ++GTC NT GS+ C C  G+   P                + C     C N  GSY
Sbjct: 125 RLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSY 184

Query: 196 VCLCPEGYVAMP 207
            C C  G+  +P
Sbjct: 185 QCRCRPGWQPIP 196



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYE 39
           C DVDEC S Q  C     C NT GSY+CRC P ++
Sbjct: 207 CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242


>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains
           6 protein.
          Length = 1229

 Score = 76.6 bits (180), Expect = 7e-14
 Identities = 56/172 (32%), Positives = 76/172 (44%), Gaps = 17/172 (9%)

Query: 3   GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C DVDEC +  + C +G C+NTQGS+ C C   YEL +DG  CY   +       + 
Sbjct: 175 GKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRI-EMEIVNSCEA 232

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGPGYQ 117
            +G   C      +  G +  C C  G         C +      S   +Q+C   PG  
Sbjct: 233 NNGG--CSHGCSHTSAGPL--CTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGY 288

Query: 118 PVLEPPSYVVTL-----ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
                  Y ++       D+DECA+  G C H  CTN  GSF C+C AG+ L
Sbjct: 289 ECGCYAGYRLSADGCGCEDVDECASSRGGCEHH-CTNLAGSFQCSCEAGYRL 339



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 63/212 (29%), Positives = 79/212 (37%), Gaps = 27/212 (12%)

Query: 8   DVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA---------RCYG 57
           DVDEC++    CQ+ +C+NT GSY C C P + L +D   C                C  
Sbjct: 56  DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 114

Query: 58  KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
               R   + CR   +L EDG             G+    C      A    C    GYQ
Sbjct: 115 LTITRHRCQ-CRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLA---RCECHVGYQ 170

Query: 118 PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP------XXXXX 171
              +  +      D+DECAA    CAHG C NT GSF C C AG+ L             
Sbjct: 171 LAADGKA----CEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEME 225

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      C  G C +     +C CP GY
Sbjct: 226 IVNSCEANNGGCSHG-CSHTSAGPLCTCPRGY 256



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 56/224 (25%), Positives = 84/224 (37%), Gaps = 21/224 (9%)

Query: 2   PGFNC-TDVDECKSPQSCQYGQ------CIN-TQGSYTCRCPPNYELVSDGTACYD---- 49
           PGF   TD   C +  SC  G       C+  T   + C+C P ++L  DG  C      
Sbjct: 84  PGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPC 143

Query: 50  -SRKARCYGKVDLRSGTETCRD--SDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAY 106
            +R   C  +  +  G   C      +L+ DG          A        C      ++
Sbjct: 144 ANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQG-SF 202

Query: 107 RQLCPGGPGYQPVLEPPS-YVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
           + +C  G  Y+   +    Y + +  ++ C A+ G C+HG C++T    +CTC  G+ L 
Sbjct: 203 KCVCHAG--YELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELD 259

Query: 166 PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                            C   VC N PG Y C C  GY    +G
Sbjct: 260 TDQRTCIDVDDCADSPCCQQ-VCTNNPGGYECGCYAGYRLSADG 302



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 56/213 (26%), Positives = 81/213 (38%), Gaps = 21/213 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARC-Y 56
           G +C     C +       +C   +G   C C   Y+L +DG AC D     +  A+C +
Sbjct: 134 GRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAH 193

Query: 57  GKVDLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDP----CPEPGSE-AYRQLC 110
           G ++ +   +  C    EL  DG     C  +     N C+     C    S  +   LC
Sbjct: 194 GCLNTQGSFKCVCHAGYELGADGRQ---CYRIEMEIVNSCEANNGGCSHGCSHTSAGPLC 250

Query: 111 PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
               GY+  L+      T  D+D+CA  +  C    CTN  G + C C AG+ L+     
Sbjct: 251 TCPRGYE--LDTDQR--TCIDVDDCA--DSPCCQQVCTNNPGGYECGCYAGYRLSADGCG 304

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                            C NL GS+ C C  GY
Sbjct: 305 CEDVDECASSRGGCEHHCTNLAGSFQCSCEAGY 337



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 2/46 (4%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G  C DVDEC S +  C++  C N  GS+ C C   Y L  D   C
Sbjct: 302 GCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHEDRRGC 346



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 31/106 (29%), Positives = 39/106 (36%), Gaps = 7/106 (6%)

Query: 107 RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
           R  C   PG+Q + E   + V  +    CA   G C H  C    G   C C  G+ LA 
Sbjct: 119 RHRCQCRPGFQ-LQEDGRHCVRRSP---CANRNGSCMH-RCQVVRGLARCECHVGYQLAA 173

Query: 167 XXXXXXXXXXXXRPDV-CGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
                            C  G C N  GS+ C+C  GY    +G Q
Sbjct: 174 DGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQ 218


>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains
           6 protein.
          Length = 1229

 Score = 76.6 bits (180), Expect = 7e-14
 Identities = 56/172 (32%), Positives = 76/172 (44%), Gaps = 17/172 (9%)

Query: 3   GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C DVDEC +  + C +G C+NTQGS+ C C   YEL +DG  CY   +       + 
Sbjct: 175 GKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRI-EMEIVNSCEA 232

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGPGYQ 117
            +G   C      +  G +  C C  G         C +      S   +Q+C   PG  
Sbjct: 233 NNGG--CSHGCSHTSAGPL--CTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGY 288

Query: 118 PVLEPPSYVVTL-----ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
                  Y ++       D+DECA+  G C H  CTN  GSF C+C AG+ L
Sbjct: 289 ECGCYAGYRLSADGCGCEDVDECASSRGGCEHH-CTNLAGSFQCSCEAGYRL 339



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 63/212 (29%), Positives = 79/212 (37%), Gaps = 27/212 (12%)

Query: 8   DVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA---------RCYG 57
           DVDEC++    CQ+ +C+NT GSY C C P + L +D   C                C  
Sbjct: 56  DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 114

Query: 58  KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
               R   + CR   +L EDG             G+    C      A    C    GYQ
Sbjct: 115 LTITRHRCQ-CRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLA---RCECHVGYQ 170

Query: 118 PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP------XXXXX 171
              +  +      D+DECAA    CAHG C NT GSF C C AG+ L             
Sbjct: 171 LAADGKA----CEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEME 225

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      C  G C +     +C CP GY
Sbjct: 226 IVNSCEANNGGCSHG-CSHTSAGPLCTCPRGY 256



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 56/224 (25%), Positives = 84/224 (37%), Gaps = 21/224 (9%)

Query: 2   PGFNC-TDVDECKSPQSCQYGQ------CIN-TQGSYTCRCPPNYELVSDGTACYD---- 49
           PGF   TD   C +  SC  G       C+  T   + C+C P ++L  DG  C      
Sbjct: 84  PGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPC 143

Query: 50  -SRKARCYGKVDLRSGTETCRD--SDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAY 106
            +R   C  +  +  G   C      +L+ DG          A        C      ++
Sbjct: 144 ANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQG-SF 202

Query: 107 RQLCPGGPGYQPVLEPPS-YVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
           + +C  G  Y+   +    Y + +  ++ C A+ G C+HG C++T    +CTC  G+ L 
Sbjct: 203 KCVCHAG--YELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELD 259

Query: 166 PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                            C   VC N PG Y C C  GY    +G
Sbjct: 260 TDQRTCIDVDDCADSPCCQQ-VCTNNPGGYECGCYAGYRLSADG 302



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 56/213 (26%), Positives = 81/213 (38%), Gaps = 21/213 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARC-Y 56
           G +C     C +       +C   +G   C C   Y+L +DG AC D     +  A+C +
Sbjct: 134 GRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAH 193

Query: 57  GKVDLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDP----CPEPGSE-AYRQLC 110
           G ++ +   +  C    EL  DG     C  +     N C+     C    S  +   LC
Sbjct: 194 GCLNTQGSFKCVCHAGYELGADGRQ---CYRIEMEIVNSCEANNGGCSHGCSHTSAGPLC 250

Query: 111 PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
               GY+  L+      T  D+D+CA  +  C    CTN  G + C C AG+ L+     
Sbjct: 251 TCPRGYE--LDTDQR--TCIDVDDCA--DSPCCQQVCTNNPGGYECGCYAGYRLSADGCG 304

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                            C NL GS+ C C  GY
Sbjct: 305 CEDVDECASSRGGCEHHCTNLAGSFQCSCEAGY 337



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 2/46 (4%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G  C DVDEC S +  C++  C N  GS+ C C   Y L  D   C
Sbjct: 302 GCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHEDRRGC 346



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 31/106 (29%), Positives = 39/106 (36%), Gaps = 7/106 (6%)

Query: 107 RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
           R  C   PG+Q + E   + V  +    CA   G C H  C    G   C C  G+ LA 
Sbjct: 119 RHRCQCRPGFQ-LQEDGRHCVRRSP---CANRNGSCMH-RCQVVRGLARCECHVGYQLAA 173

Query: 167 XXXXXXXXXXXXRPDV-CGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
                            C  G C N  GS+ C+C  GY    +G Q
Sbjct: 174 DGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQ 218


>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
           protein.
          Length = 1640

 Score = 76.6 bits (180), Expect = 7e-14
 Identities = 56/172 (32%), Positives = 76/172 (44%), Gaps = 17/172 (9%)

Query: 3   GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C DVDEC +  + C +G C+NTQGS+ C C   YEL +DG  CY   +       + 
Sbjct: 355 GKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRI-EMEIVNSCEA 412

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGPGYQ 117
            +G   C      +  G +  C C  G         C +      S   +Q+C   PG  
Sbjct: 413 NNGG--CSHGCSHTSAGPL--CTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGY 468

Query: 118 PVLEPPSYVVTL-----ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
                  Y ++       D+DECA+  G C H  CTN  GSF C+C AG+ L
Sbjct: 469 ECGCYAGYRLSADGCGCEDVDECASSRGGCEHH-CTNLAGSFQCSCEAGYRL 519



 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 67/222 (30%), Positives = 83/222 (37%), Gaps = 31/222 (13%)

Query: 2   PGFN---CT-DVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA--- 53
           PGF    C  DVDEC++    CQ+ +C+NT GSY C C P + L +D   C         
Sbjct: 226 PGFQGPRCQYDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALG 284

Query: 54  ------RCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR 107
                  C      R   + CR   +L EDG             G+    C      A  
Sbjct: 285 NGGCQHHCVQLTITRHRCQ-CRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLA-- 341

Query: 108 QLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP- 166
             C    GYQ   +  +      D+DECAA    CAHG C NT GSF C C AG+ L   
Sbjct: 342 -RCECHVGYQLAADGKA----CEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGAD 395

Query: 167 -----XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                                C  G C +     +C CP GY
Sbjct: 396 GRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGY 436



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 56/224 (25%), Positives = 84/224 (37%), Gaps = 21/224 (9%)

Query: 2   PGFNC-TDVDECKSPQSCQYGQ------CIN-TQGSYTCRCPPNYELVSDGTACYD---- 49
           PGF   TD   C +  SC  G       C+  T   + C+C P ++L  DG  C      
Sbjct: 264 PGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPC 323

Query: 50  -SRKARCYGKVDLRSGTETCRD--SDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAY 106
            +R   C  +  +  G   C      +L+ DG          A        C      ++
Sbjct: 324 ANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQG-SF 382

Query: 107 RQLCPGGPGYQPVLEPPS-YVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
           + +C  G  Y+   +    Y + +  ++ C A+ G C+HG C++T    +CTC  G+ L 
Sbjct: 383 KCVCHAG--YELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELD 439

Query: 166 PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                            C   VC N PG Y C C  GY    +G
Sbjct: 440 TDQRTCIDVDDCADSPCCQQ-VCTNNPGGYECGCYAGYRLSADG 482



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 56/213 (26%), Positives = 81/213 (38%), Gaps = 21/213 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARC-Y 56
           G +C     C +       +C   +G   C C   Y+L +DG AC D     +  A+C +
Sbjct: 314 GRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAH 373

Query: 57  GKVDLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDP----CPEPGSE-AYRQLC 110
           G ++ +   +  C    EL  DG     C  +     N C+     C    S  +   LC
Sbjct: 374 GCLNTQGSFKCVCHAGYELGADGRQ---CYRIEMEIVNSCEANNGGCSHGCSHTSAGPLC 430

Query: 111 PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
               GY+  L+      T  D+D+CA  +  C    CTN  G + C C AG+ L+     
Sbjct: 431 TCPRGYE--LDTDQR--TCIDVDDCA--DSPCCQQVCTNNPGGYECGCYAGYRLSADGCG 484

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                            C NL GS+ C C  GY
Sbjct: 485 CEDVDECASSRGGCEHHCTNLAGSFQCSCEAGY 517



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 2/46 (4%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G  C DVDEC S +  C++  C N  GS+ C C   Y L  D   C
Sbjct: 482 GCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHEDRRGC 526



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 53/210 (25%), Positives = 72/210 (34%), Gaps = 22/210 (10%)

Query: 11  ECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC-YDSRKAR-----CYGKVDLRSG 64
           EC +      G+C+    +  C CPP ++    G  C YD  + R     C  +     G
Sbjct: 202 ECSAGLCFHGGRCV-PGSAQPCHCPPGFQ----GPRCQYDVDECRTHNGGCQHRCVNTPG 256

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAWGNY-CDP-CPEPGSEAYRQLCPGGPGYQPVLEP 122
           +  C              C      A GN  C   C +     +R  C   PG+Q + E 
Sbjct: 257 SYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHR--CQCRPGFQ-LQED 313

Query: 123 PSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
             + V  +    CA   G C H  C    G   C C  G+ LA                 
Sbjct: 314 GRHCVRRSP---CANRNGSCMH-RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLA 369

Query: 183 -CGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
            C  G C N  GS+ C+C  GY    +G Q
Sbjct: 370 QCAHG-CLNTQGSFKCVCHAGYELGADGRQ 398


>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
          Length = 1246

 Score = 76.6 bits (180), Expect = 7e-14
 Identities = 56/172 (32%), Positives = 76/172 (44%), Gaps = 17/172 (9%)

Query: 3   GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C DVDEC +  + C +G C+NTQGS+ C C   YEL +DG  CY   +       + 
Sbjct: 192 GKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRI-EMEIVNSCEA 249

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGPGYQ 117
            +G   C      +  G +  C C  G         C +      S   +Q+C   PG  
Sbjct: 250 NNGG--CSHGCSHTSAGPL--CTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGY 305

Query: 118 PVLEPPSYVVTL-----ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
                  Y ++       D+DECA+  G C H  CTN  GSF C+C AG+ L
Sbjct: 306 ECGCYAGYRLSADGCGCEDVDECASSRGGCEHH-CTNLAGSFQCSCEAGYRL 356



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 63/212 (29%), Positives = 79/212 (37%), Gaps = 27/212 (12%)

Query: 8   DVDECKSPQS-CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA---------RCYG 57
           DVDEC++    CQ+ +C+NT GSY C C P + L +D   C                C  
Sbjct: 73  DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 131

Query: 58  KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
               R   + CR   +L EDG             G+    C      A    C    GYQ
Sbjct: 132 LTITRHRCQ-CRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLA---RCECHVGYQ 187

Query: 118 PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP------XXXXX 171
              +  +      D+DECAA    CAHG C NT GSF C C AG+ L             
Sbjct: 188 LAADGKA----CEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEME 242

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      C  G C +     +C CP GY
Sbjct: 243 IVNSCEANNGGCSHG-CSHTSAGPLCTCPRGY 273



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 56/224 (25%), Positives = 84/224 (37%), Gaps = 21/224 (9%)

Query: 2   PGFNC-TDVDECKSPQSCQYGQ------CIN-TQGSYTCRCPPNYELVSDGTACYD---- 49
           PGF   TD   C +  SC  G       C+  T   + C+C P ++L  DG  C      
Sbjct: 101 PGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPC 160

Query: 50  -SRKARCYGKVDLRSGTETCRD--SDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAY 106
            +R   C  +  +  G   C      +L+ DG          A        C      ++
Sbjct: 161 ANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQG-SF 219

Query: 107 RQLCPGGPGYQPVLEPPS-YVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
           + +C  G  Y+   +    Y + +  ++ C A+ G C+HG C++T    +CTC  G+ L 
Sbjct: 220 KCVCHAG--YELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELD 276

Query: 166 PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                            C   VC N PG Y C C  GY    +G
Sbjct: 277 TDQRTCIDVDDCADSPCCQQ-VCTNNPGGYECGCYAGYRLSADG 319



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 56/213 (26%), Positives = 81/213 (38%), Gaps = 21/213 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARC-Y 56
           G +C     C +       +C   +G   C C   Y+L +DG AC D     +  A+C +
Sbjct: 151 GRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAH 210

Query: 57  GKVDLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDP----CPEPGSE-AYRQLC 110
           G ++ +   +  C    EL  DG     C  +     N C+     C    S  +   LC
Sbjct: 211 GCLNTQGSFKCVCHAGYELGADGRQ---CYRIEMEIVNSCEANNGGCSHGCSHTSAGPLC 267

Query: 111 PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX 170
               GY+  L+      T  D+D+CA  +  C    CTN  G + C C AG+ L+     
Sbjct: 268 TCPRGYE--LDTDQR--TCIDVDDCA--DSPCCQQVCTNNPGGYECGCYAGYRLSADGCG 321

Query: 171 XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                            C NL GS+ C C  GY
Sbjct: 322 CEDVDECASSRGGCEHHCTNLAGSFQCSCEAGY 354



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 2/46 (4%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G  C DVDEC S +  C++  C N  GS+ C C   Y L  D   C
Sbjct: 319 GCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHEDRRGC 363



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 31/106 (29%), Positives = 39/106 (36%), Gaps = 7/106 (6%)

Query: 107 RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
           R  C   PG+Q + E   + V  +    CA   G C H  C    G   C C  G+ LA 
Sbjct: 136 RHRCQCRPGFQ-LQEDGRHCVRRSP---CANRNGSCMH-RCQVVRGLARCECHVGYQLAA 190

Query: 167 XXXXXXXXXXXXRPDV-CGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
                            C  G C N  GS+ C+C  GY    +G Q
Sbjct: 191 DGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQ 235


>X94630-1|CAA64333.1|  835|Homo sapiens seven-span transmembrane
           protein protein.
          Length = 835

 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 63/214 (29%), Positives = 82/214 (38%), Gaps = 42/214 (19%)

Query: 2   PGFNCTDVDECKSPQ--SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           P   C D++EC +P   SC ++  C NT+GSY C C P YE VS               K
Sbjct: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGA-------------K 104

Query: 59  VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                   TC+D DE  ++  +   C S G             GS      C   PG++ 
Sbjct: 105 TFKNESENTCQDVDECQQNPRL---CKSYGTCVNTL-------GSYT----CQCLPGFKF 150

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
           + E P       D++EC + +  C   T C N  GS+ C C  GW   P           
Sbjct: 151 IPEDPK---VCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 207

Query: 178 XRPDVCGPG--------VCRNLPGSYVCLCPEGY 203
              D C  G        VC N  GSY C C  G+
Sbjct: 208 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 58/192 (30%), Positives = 83/192 (43%), Gaps = 25/192 (13%)

Query: 26  TQGSYTCR--CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAAC 83
           TQ S  C   CP N   V+  TAC  +     + ++ + + TETC   D+++E  T +  
Sbjct: 20  TQDSRGCARWCPQNSSCVN-ATACRCNPGFSSFSEI-ITTPTETC---DDINECATPSKV 74

Query: 84  CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV----TLADIDECAAHE 139
            C      G + D     GS  Y  +C   PGY+PV    ++      T  D+DEC  + 
Sbjct: 75  SC------GKFSDCWNTEGS--YDCVC--SPGYEPVSGAKTFKNESENTCQDVDECQQNP 124

Query: 140 GLC-AHGTCTNTFGSFVCTCGAGWSLAPX--XXXXXXXXXXXRPDVCGPGV-CRNLPGSY 195
            LC ++GTC NT GS+ C C  G+   P                + C     C N  GSY
Sbjct: 125 RLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSY 184

Query: 196 VCLCPEGYVAMP 207
            C C  G+  +P
Sbjct: 185 QCRCRPGWQPIP 196



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYE 39
           C DVDEC S Q  C     C NT GSY+CRC P ++
Sbjct: 207 CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242


>AK074499-1|BAC11024.1|  636|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90018 fis, clone HEMBA1000732, highly similar to
           Homo sapiens mRNA for latent transforming growth
           factor-beta ).
          Length = 636

 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 46/142 (32%), Positives = 59/142 (41%), Gaps = 9/142 (6%)

Query: 74  LSEDGTMAACCCSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLAD 131
           L+ + T   CCC+VG  WG+ C    CP   +  Y+ LCP G GY   L P   +    D
Sbjct: 209 LARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGY---LAPSGDLSLRRD 265

Query: 132 IDECAA-HEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRPDVCGPGVCR 189
           +DEC    + +C  G C NT   + C C  G+                     C  G C 
Sbjct: 266 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 325

Query: 190 NLPGSYVCLCPEGYVAMPNGSQ 211
           N  GSY C C    V   +GSQ
Sbjct: 326 NTVGSYHCTCEPPLVL--DGSQ 345



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 42/128 (32%), Positives = 56/128 (43%), Gaps = 19/128 (14%)

Query: 6   CTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYEL-------VSDGTACYDSRKARCYG 57
           C D DEC   + +C+ G+C+NT GSY C C P   L       VS+ +   D     C+ 
Sbjct: 306 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 365

Query: 58  KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
           +V    G +       L    T   CCC  G AWG  C  CP   S+ +  L       +
Sbjct: 366 EV----GADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEAL-------R 414

Query: 118 PVLEPPSY 125
            VL PP+Y
Sbjct: 415 NVLRPPAY 422



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 41/103 (39%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXX 171
           GG G  P L  P      AD+DEC+  E LC  G CTNT GSF C C  G    P     
Sbjct: 3   GGAGGGPGLRTPCP----ADVDECS-EEDLCQSGICTNTDGSFECICPPGHRAGPDLASC 57

Query: 172 XXXXXXXR--PDVCGPGVCRNLPGSYVCL--CPEGYVAMPNGS 210
                     P +C    C N PGSY C+  C  GY A P G+
Sbjct: 58  LDVDECRERGPALCRSQRCENSPGSYRCVRDCDPGYHAGPEGT 100



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 2/64 (3%)

Query: 8  DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
          DVDEC     CQ G C NT GS+ C CPP +    D  +C D  + R  G    RS  + 
Sbjct: 18 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRS--QR 75

Query: 68 CRDS 71
          C +S
Sbjct: 76 CENS 79



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 34/118 (28%), Positives = 48/118 (40%), Gaps = 14/118 (11%)

Query: 97  PCPEPGSEAYRQ-LCPGG-----PGYQPVLEPPSY-----VVTLADIDECAAH-EGLCAH 144
           PCP    E   + LC  G      G    + PP +     + +  D+DEC      LC  
Sbjct: 14  PCPADVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRS 73

Query: 145 GTCTNTFGSFVCT--CGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
             C N+ GS+ C   C  G+   P               VCG  +C N+ GS++C+CP
Sbjct: 74  QRCENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVCGAALCENVEGSFLCVCP 131



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 38/117 (32%), Positives = 49/117 (41%), Gaps = 14/117 (11%)

Query: 55  CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGN---YC---DPCPEPGSEAYR- 107
           C   VD  S  + C+     + DG+   C C  G   G     C   D C E G    R 
Sbjct: 15  CPADVDECSEEDLCQSGICTNTDGSFE-CICPPGHRAGPDLASCLDVDECRERGPALCRS 73

Query: 108 QLCPGGPG-YQPVLE-PPSYVV----TLADIDECAAHEGLCAHGTCTNTFGSFVCTC 158
           Q C   PG Y+ V +  P Y      T  D++EC   +G+C    C N  GSF+C C
Sbjct: 74  QRCENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVCGAALCENVEGSFLCVC 130



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 5/49 (10%)

Query: 5   NCTDVDECKS--PQSCQYGQCINTQGSYTC--RCPPNYELVSDGTACYD 49
           +C DVDEC+   P  C+  +C N+ GSY C   C P Y    +GT C D
Sbjct: 56  SCLDVDECRERGPALCRSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDD 103



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           + +EC     C  G+C+     +TCRC   Y L     AC D  +       +  + +  
Sbjct: 545 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECD-----EAEAASPL 599

Query: 68  CRDSDELSEDGTMAACCCSVGAA 90
           C ++  L+ DG+   C C  G A
Sbjct: 600 CVNARCLNTDGSF-RCICRPGFA 621



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 8/84 (9%)

Query: 8   DVDECK--SPQSCQYGQCINTQGSYTCRCPPNYELVS------DGTACYDSRKARCYGKV 59
           DVDEC+    Q C+ G C+NT   Y+C C   Y   +      D   C D   A   G+ 
Sbjct: 265 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 324

Query: 60  DLRSGTETCRDSDELSEDGTMAAC 83
               G+  C     L  DG+   C
Sbjct: 325 VNTVGSYHCTCEPPLVLDGSQRRC 348



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 4/50 (8%)

Query: 6   CTDVDECKSPQS----CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR 51
           C D++EC   ++    C   +C+NT GS+ C C P +        C  +R
Sbjct: 584 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 633



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 1/39 (2%)

Query: 2   PGFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYE 39
           P   C DV+EC++ Q  C    C N +GS+ C CP + E
Sbjct: 97  PEGTCDDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 135



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 15/37 (40%), Positives = 20/37 (54%)

Query: 127 VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS 163
           V + + DE  A   LC +  C NT GSF C C  G++
Sbjct: 585 VDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 621



 Score = 34.7 bits (76), Expect = 0.27
 Identities = 19/77 (24%), Positives = 28/77 (36%), Gaps = 5/77 (6%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGP----G 186
           + +EC   +G C +G C      F C C  G+ L                +   P     
Sbjct: 545 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 603

Query: 187 VCRNLPGSYVCLCPEGY 203
            C N  GS+ C+C  G+
Sbjct: 604 RCLNTDGSFRCICRPGF 620


>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
          Length = 2471

 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 64/210 (30%), Positives = 84/210 (40%), Gaps = 28/210 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C TDV+EC  P  CQ+G  C+N  GSY C+C   +     G  C DS    C     
Sbjct: 176 GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFT----GQYC-DSLYVPCAPSPC 230

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGY 116
           +  GT  CR + + + +     C C  G   G+ C    D CP    +    +C  G   
Sbjct: 231 VNGGT--CRQTGDFTFE-----CNCLPGFE-GSTCERNIDDCPNHRCQN-GGVCVDGVNT 281

Query: 117 QPVLEPPSYVVTLA--DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP +       D+DEC      C +G TC N  G + C C  GWS          
Sbjct: 282 YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDD 341

Query: 174 XXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                    C PG  C +   S+ C+CPEG
Sbjct: 342 CAFAS----CTPGSTCIDRVASFSCMCPEG 367



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 55/204 (26%), Positives = 74/204 (36%), Gaps = 20/204 (9%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C+D +DEC S      G+CI+    Y C C P    V+      D     C   + +
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQLCPGGPGYQPV 119
             G    R S   S   T   C   +     N C        G   +R +CP GP +   
Sbjct: 661 -DGIN--RYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHH--- 714

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
             P  Y    + ++EC ++   C HG CT     + C C AGW                 
Sbjct: 715 --PSCY----SQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW--VGINCEVDKNECLSN 764

Query: 180 PDVCGPGVCRNLPGSYVCLCPEGY 203
           P   G G C NL   Y C C +G+
Sbjct: 765 PCQNG-GTCDNLVNGYRCTCKKGF 787



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 63/233 (27%), Positives = 89/233 (38%), Gaps = 38/233 (16%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY------ELVSD--------GTAC 47
            G  CT D+DEC S     +G C NTQGSY C CPP +      E + D        G +C
Sbjct: 867  GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSC 926

Query: 48   YD---SRKARCYG-------KVDLRSG-TETCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
             D   +    C         + D+    +E C++    S+      C C  G   G +C+
Sbjct: 927  MDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD-GVHCE 985

Query: 97   ----PCPEPGSEAYRQLCPGGPGYQPVLEPPSYV--VTLADIDECAAHEGLCAHGTCTNT 150
                 C E  S      C  G      L P  +     L +I+EC++H  L   GTC + 
Sbjct: 986  NNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCL-NEGTCVDG 1043

Query: 151  FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G++ C+C  G++               R      G C        CLCP G+
Sbjct: 1044 LGTYRCSCPLGYT---GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 58/215 (26%), Positives = 84/215 (39%), Gaps = 36/215 (16%)

Query: 3   GFNCT-DVDECKSPQS--CQY-GQCINTQGSYTCRCPPNY---ELVSDGTACYD---SRK 52
           G +CT DVDEC    S  C++ G+C+NT G++ C C   Y       D   C+       
Sbjct: 409 GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468

Query: 53  ARCYGKVDLRSGTETCRDSDELSEDGTMAACC-CSVGAAWGNYCDPCPEPGSEAYRQLCP 111
           A C  K+    G  TC     L   G     C   +     N C    +   +  R  C 
Sbjct: 469 ATCLDKI----GGFTC-----LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519

Query: 112 GGPGYQ-PVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXX 169
             PG+  PV +         DID+C++    C +G  C +    + C C  G++      
Sbjct: 520 CPPGFTGPVCQ--------IDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFT----GV 565

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                     PD C  G C++   SY C+C  GY+
Sbjct: 566 LCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM 600



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 62/209 (29%), Positives = 78/209 (37%), Gaps = 28/209 (13%)

Query: 6   CT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVDL 61
           CT DVDEC   P +CQ G  C N  G Y C C   +          D   A C  G   +
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI 354

Query: 62  -RSGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
            R  + +C   +   + G +      C S     G  CD  P  G   Y   CP G    
Sbjct: 355 DRVASFSCMCPE--GKAGLLCHLDDACISNPCHKGALCDTNPLNGQ--YICTCPQGYKGA 410

Query: 118 PVLEPPSYVVTLADIDECA-AHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
              E         D+DECA A+   C H G C NT G+F C C  G++  P         
Sbjct: 411 DCTE---------DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA-GP---RCEMDI 457

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                D C     C +  G + CLC  G+
Sbjct: 458 NECHSDPCQNDATCLDKIGGFTCLCMPGF 486



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 51/215 (23%), Positives = 81/215 (37%), Gaps = 35/215 (16%)

Query: 1   MPGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           MPGF   +C  +++EC+S      GQC++    + C CPP +     G  C         
Sbjct: 483 MPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGPVC--------- 529

Query: 57  GKVDLRSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEAYRQLC 110
            ++D+   + T C +  +  +      C C+ G   G  C    D C P+P    +   C
Sbjct: 530 -QIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFT-GVLCEENIDNCDPDP---CHHGQC 584

Query: 111 PGGPGYQPVLEPPSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXX 168
             G      +  P Y+  +    IDEC +   L   G C +    + C C  G S     
Sbjct: 585 QDGIDSYTCICNPGYMGAICSDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPGTS----G 639

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                       + C  G+C +    Y C+C  G+
Sbjct: 640 VNCEINFDDCASNPCIHGICMDGINRYSCVCSPGF 674



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 58/208 (27%), Positives = 76/208 (36%), Gaps = 24/208 (11%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  D +EC S      G C N    Y C C   ++    G  C       C     L
Sbjct: 751 GINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK----GYNC-QVNIDECASNPCL 805

Query: 62  RSGTETCRDSDELSEDGTMAACCCS-VGAAWGNYCDPC-PEPGSEAYRQLCPGGPGYQ-- 117
             G  TC   D++S  G    C     G        PC P P   A   +C   P ++  
Sbjct: 806 NQG--TC--FDDIS--GYTCHCVLPYTGKNCQTVLAPCSPNPCENA--AVCKESPNFESY 857

Query: 118 PVLEPPSY--VVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             L  P +       DIDEC + +    HG C NT GS++C C  G+S            
Sbjct: 858 TCLCAPGWQGQRCTIDIDECIS-KPCMNHGLCHNTQGSYMCECPPGFS--GMDCEEDIDD 914

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C +   ++ CLC  G+
Sbjct: 915 CLANPCQNG-GSCMDGVNTFSCLCLPGF 941



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 28/210 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G+NC  ++DEC S      G C +    YTC C   Y     G  C  +  A C    + 
Sbjct: 789 GYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPY----TGKNC-QTVLAPC--SPNP 841

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGY 116
                 C++S           C C+ G  W G  C    D C       +  LC    G 
Sbjct: 842 CENAAVCKESPNFES----YTCLCAPG--WQGQRCTIDIDECISKPCMNH-GLCHNTQGS 894

Query: 117 QPVLEPPSY--VVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP +  +    DID+C A+   C + G+C +   +F C C  G++          
Sbjct: 895 YMCECPPGFSGMDCEEDIDDCLANP--CQNGGSCMDGVNTFSCLCLPGFT--GDKCQTDM 950

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                 P   G G C +   SY C C  G+
Sbjct: 951 NECLSEPCKNG-GTCSDYVNSYTCKCQAGF 979



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 51/211 (24%), Positives = 76/211 (36%), Gaps = 35/211 (16%)

Query: 8    DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
            +++EC S      G C++  G+Y C CP  Y                C   V+L S    
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGY------------TGKNCQTLVNLCS-RSP 1071

Query: 68   CRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSE---------AYRQLCPGGP 114
            C++     +    + C C  G A G YCD     C    S           +  +C    
Sbjct: 1072 CKNKGTCVQKKAESQCLCPSGWA-GAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130

Query: 115  GYQPVLEPPSYVVTLAD--IDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
                   P  Y  +  +  +DECA++   C HG TC++  G + C C  G+         
Sbjct: 1131 NTHYCQCPLGYTGSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQ--GVNCEY 1186

Query: 172  XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                   +P   G G C +L   + C CP G
Sbjct: 1187 EVDECQNQPCQNG-GTCIDLVNHFKCSCPPG 1216



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 7/83 (8%)

Query: 133 DECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRN 190
           D C +H   CA+G TCT     F C C  G++                P  C  G  C N
Sbjct: 146 DACLSHP--CANGSTCTTVANQFSCKCLTGFT---GQKCETDVNECDIPGHCQHGGTCLN 200

Query: 191 LPGSYVCLCPEGYVAMPNGSQYL 213
           LPGSY C C +G+      S Y+
Sbjct: 201 LPGSYQCQCLQGFTGQYCDSLYV 223



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 57/218 (26%), Positives = 74/218 (33%), Gaps = 29/218 (13%)

Query: 1    MPGFN---C-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            +PGF    C TD++EC S      G C +   SYTC+C   +    DG  C ++    C 
Sbjct: 938  LPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----DGVHC-ENNINECT 992

Query: 57   GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC-DPCPEPGSE--AYRQLCPGG 113
                   G  TC D           +C C VG   G++C     E  S        C  G
Sbjct: 993  ESSCFNGG--TCVDGI------NSFSCLCPVGFT-GSFCLHEINECSSHPCLNEGTCVDG 1043

Query: 114  PGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLA----PXX 168
             G      P  Y                C + GTC        C C +GW+ A    P  
Sbjct: 1044 LGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNV 1103

Query: 169  X--XXXXXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                           +C   GVC N   ++ C CP GY
Sbjct: 1104 SCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY 1141



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 52/213 (24%), Positives = 68/213 (31%), Gaps = 25/213 (11%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC T V+ C        G C+  +    C CP  +     G  C D     C      
Sbjct: 1057 GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWA----GAYC-DVPNVSCDIAASR 1111

Query: 62   RSGT--ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP----- 114
            R       C+ S      G    C C +G   G+YC+   E   E     C  G      
Sbjct: 1112 RGVLVEHLCQHSGVCINAGNTHYCQCPLGYT-GSYCE---EQLDECASNPCQHGATCSDF 1167

Query: 115  --GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXX 170
              GY+    P    V    ++DEC      C +G TC +    F C+C  G         
Sbjct: 1168 IGGYRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG--TRGLLCE 1223

Query: 171  XXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                     P     G C +  G Y C C  G+
Sbjct: 1224 ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF 1256



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 3/56 (5%)

Query: 151 FGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           F S+ C C  GW                +P +   G+C N  GSY+C CP G+  M
Sbjct: 854 FESYTCLCAPGWQ--GQRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGFSGM 906



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 50/209 (23%), Positives = 72/209 (34%), Gaps = 25/209 (11%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G  C   D C S        C      ++C+C   +     G  C ++    C      +
Sbjct: 139 GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKC-ETDVNECDIPGHCQ 193

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PC-PEPGSEAYRQLCPGGPGYQ 117
            G  TC     L+  G+   C C  G   G YCD    PC P P          G   ++
Sbjct: 194 HGG-TC-----LNLPGSYQ-CQCLQGFT-GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 245

Query: 118 PVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               P     T   +ID+C  H   C +G  C +   ++ C C   W+            
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHR--CQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDE 301

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
              +P+ C   G C N  G Y C+C  G+
Sbjct: 302 CLLQPNACQNGGTCANRNGGYGCVCVNGW 330



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 37/147 (25%), Positives = 50/147 (34%), Gaps = 12/147 (8%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCI---NTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
            G +C T VD C        G C    N    + CRCPP +      ++C   +  +    
Sbjct: 1298 GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQC 1357

Query: 59   VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCP-GGPGYQ 117
            V   SG      S    E G     C S     G  C P  +P   + +   P  G   +
Sbjct: 1358 VHTASGPRCFCPSPRDCESG-----CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412

Query: 118  PVLEPPSYVVTLADIDECA--AHEGLC 142
                PPS          CA  A +G+C
Sbjct: 1413 LYTAPPSTPPATCLSQYCADKARDGVC 1439


>AB065966-1|BAC06178.1|  837|Homo sapiens seven transmembrane helix
           receptor protein.
          Length = 837

 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 63/214 (29%), Positives = 82/214 (38%), Gaps = 42/214 (19%)

Query: 2   PGFNCTDVDECKSPQ--SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           P   C D++EC +P   SC ++  C NT+GSY C C P YE VS               K
Sbjct: 60  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGA-------------K 106

Query: 59  VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                   TC+D DE  ++  +   C S G             GS      C   PG++ 
Sbjct: 107 TFKNESENTCQDVDECQQNPRL---CKSYGTCVNTL-------GSYT----CQCLPGFKF 152

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
           + E P       D++EC + +  C   T C N  GS+ C C  GW   P           
Sbjct: 153 IPEDPK---VCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 209

Query: 178 XRPDVCGPG--------VCRNLPGSYVCLCPEGY 203
              D C  G        VC N  GSY C C  G+
Sbjct: 210 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 243



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 58/192 (30%), Positives = 83/192 (43%), Gaps = 25/192 (13%)

Query: 26  TQGSYTCR--CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAAC 83
           TQ S  C   CP N   V+  TAC  +     + ++ + + TETC   D+++E  T +  
Sbjct: 22  TQDSRGCARWCPQNSSCVN-ATACRCNPGFSSFSEI-ITTPTETC---DDINECATPSKV 76

Query: 84  CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV----TLADIDECAAHE 139
            C      G + D     GS  Y  +C   PGY+PV    ++      T  D+DEC  + 
Sbjct: 77  SC------GKFSDCWNTEGS--YDCVC--SPGYEPVSGAKTFKNESENTCQDVDECQQNP 126

Query: 140 GLC-AHGTCTNTFGSFVCTCGAGWSLAPX--XXXXXXXXXXXRPDVCGPGV-CRNLPGSY 195
            LC ++GTC NT GS+ C C  G+   P                + C     C N  GSY
Sbjct: 127 RLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSY 186

Query: 196 VCLCPEGYVAMP 207
            C C  G+  +P
Sbjct: 187 QCRCRPGWQPIP 198



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYE 39
           C DVDEC S Q  C     C NT GSY+CRC P ++
Sbjct: 209 CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 244


>X81479-1|CAA57232.1|  886|Homo sapiens EMR1 protein.
          Length = 886

 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 69/239 (28%), Positives = 89/239 (37%), Gaps = 33/239 (13%)

Query: 2   PGFNCTDVDEC-KSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           PG  C D+DEC +SPQ C     C N  G Y C C   +   +     +   K   +   
Sbjct: 74  PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGND--WVPGKPGNFSCT 131

Query: 60  DLRS--GTETCRDSDELSEDGTMAACCCSVGAAWGNY--------CDP--CPEPGS---- 103
           D+     +  C +  +        +C C VG    N          DP  CPE  +    
Sbjct: 132 DINECLTSRVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVNECADPRACPEHATCNNT 191

Query: 104 -EAYRQLC-PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
              Y   C PG       L       +  DIDEC   E    + TCTNT GS+ CTC  G
Sbjct: 192 VGNYSCFCNPGFESSSGHLSCQGLKASCEDIDECT--EMCPINSTCTNTPGSYFCTCHPG 249

Query: 162 WSLAPXXXXXXXXXXXXR--------PDVCGP-GVCRNLPGSYVCLCPEGYVAMPNGSQ 211
           ++ +             R        P  CGP  +C N  GSY C C  G+   P GSQ
Sbjct: 250 FAPSSGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIVGFHPNPEGSQ 308



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 55/225 (24%), Positives = 74/225 (32%), Gaps = 30/225 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC D   C +     Y  C NT  SY C C   + L S+G   +     RC    +  
Sbjct: 32  GNNCRDSTLCPA-----YATCTNTVDSYYCTCKQGF-LSSNGQNHFKDPGVRCKDIDECS 85

Query: 63  SGTETCRDSDELSEDGTMAACCCSVG--AAWGNYCDP-------CPEPGSEAYRQLCP-- 111
              + C  +           C C  G  +  GN   P       C +       ++CP  
Sbjct: 86  QSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSRVCPEH 145

Query: 112 -------GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
                  G       +   S   T  D++ECA       H TC NT G++ C C  G+  
Sbjct: 146 SDCVNSMGSYSCSCQVGFISRNSTCEDVNECADPRACPEHATCNNTVGNYSCFCNPGFES 205

Query: 165 APXXXXXXXXXXXXRP-DVCGP-----GVCRNLPGSYVCLCPEGY 203
           +                D C         C N PGSY C C  G+
Sbjct: 206 SSGHLSCQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGF 250



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 11/83 (13%)

Query: 141 LC-AHGTCTNTFGSFVCTCGAGWSLA--------PXXXXXXXXXXXXRPDVCGP-GVCRN 190
           LC A+ TCTNT  S+ CTC  G+  +        P             P  CGP   C+N
Sbjct: 40  LCPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 99

Query: 191 LPGSYVCLCPEGYVAMPNGSQYL 213
           L G Y C C +G+ + P G+ ++
Sbjct: 100 LSGRYKCSCLDGF-SSPTGNDWV 121


>AY358898-1|AAQ89257.1|  448|Homo sapiens FBLN5 protein.
          Length = 448

 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 67/206 (32%), Positives = 85/206 (41%), Gaps = 24/206 (11%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL-- 61
           C DVDEC +    C   Q CINT+G YTC C   Y L+     C D  + R YG      
Sbjct: 125 CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG--QCLDIDECR-YGYCQQLC 181

Query: 62  ----RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL-CPGGPGY 116
                S + TC     L+EDG     C  V        +PC +     Y  L C   PGY
Sbjct: 182 ANVPGSYSCTCNPGFTLNEDG---RSCQDVNECATE--NPCVQTCVNTYGSLICRCDPGY 236

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXX 175
           +  LE     V  +D+DEC+  E LC H  C N  G++ C+C  G+ L            
Sbjct: 237 E--LEEDG--VHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINE 291

Query: 176 XXXRPDVCG-PGVCRNLPGSYVCLCP 200
              R   C     C NL G + C+ P
Sbjct: 292 CEHRNHTCNLQQTCYNLQGGFKCIDP 317



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 46/182 (25%), Positives = 68/182 (37%), Gaps = 14/182 (7%)

Query: 36  PNYELVSDGTAC---YDSRKA-RCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAW 91
           PNY  +S    C   Y   ++ +C    +  + +  C  +           C C+ G  W
Sbjct: 102 PNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY-W 160

Query: 92  --GNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV-----TLADIDECAAHEGLCAH 144
                C    E      +QLC   PG       P + +     +  D++ECA  E  C  
Sbjct: 161 LLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQ 219

Query: 145 GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
            TC NT+GS +C C  G+ L                +      C N PG+Y C CP GY+
Sbjct: 220 -TCVNTYGSLICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI 278

Query: 205 AM 206
            +
Sbjct: 279 LL 280



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/47 (48%), Positives = 27/47 (57%), Gaps = 1/47 (2%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C DV+EC +   C    C+NT GS  CRC P YEL  DG  C D
Sbjct: 202 GRSCQDVNECATENPCVQ-TCVNTYGSLICRCDPGYELEEDGVHCSD 247



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 22/48 (45%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C+D+DEC  S   CQ+ +C+N  G+Y C CPP Y L+ D  +C D
Sbjct: 242 GVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQD 288



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 49/199 (24%), Positives = 75/199 (37%), Gaps = 24/199 (12%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR-DSDELSEDGTMA 81
           C+ + G+   +C   ++L        D +  +C    + R+  E CR D   ++++G   
Sbjct: 16  CLPSPGNAQAQCTNGFDL--------DRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYL 67

Query: 82  ACCCSVGAAWGNYCDPCPEPGSEAYRQLCP--GGPGYQPVLEPP----SYVVT----LAD 131
               +     G Y +P   P S  Y    P    P Y  +  P      Y +       D
Sbjct: 68  CIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVD 127

Query: 132 IDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           +DECA     C     C NT G + C+C  G+ L              R   C   +C N
Sbjct: 128 VDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDEC---RYGYCQQ-LCAN 183

Query: 191 LPGSYVCLCPEGYVAMPNG 209
           +PGSY C C  G+    +G
Sbjct: 184 VPGSYSCTCNPGFTLNEDG 202



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 53/214 (24%), Positives = 79/214 (36%), Gaps = 21/214 (9%)

Query: 6   CTDVDECKS-PQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVDLR 62
           C D+DEC++ P++C+    C+N  G Y C   P    V  G   Y +  +  Y G     
Sbjct: 40  CLDIDECRTIPEACRGDMMCVNQNGGYLCI--PRTNPVYRGP--YSNPYSTPYSGPYPAA 95

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR----QLCPGGPGYQP 118
           +   +  +   +S       C         N C    E  +++++    Q+C    G   
Sbjct: 96  APPLSAPNYPTISRP---LICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYT 152

Query: 119 VLEPPSYVVT---LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                 Y +      DIDEC    G C    C N  GS+ CTC  G++L           
Sbjct: 153 CSCTDGYWLLEGQCLDIDEC--RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVN 209

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                + C    C N  GS +C C  GY    +G
Sbjct: 210 ECATENPCVQ-TCVNTYGSLICRCDPGYELEEDG 242


>DQ217942-1|ABB70739.1|  886|Homo sapiens EGF-like module containing
           mucin-like hormone receptor-like 1 protein.
          Length = 886

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 69/239 (28%), Positives = 89/239 (37%), Gaps = 33/239 (13%)

Query: 2   PGFNCTDVDEC-KSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           PG  C D+DEC +SPQ C     C N  G Y C C   +   +     +   K   +   
Sbjct: 74  PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGND--WVPGKPGNFSCT 131

Query: 60  DLRS--GTETCRDSDELSEDGTMAACCCSVGAAWGN--------YCDP--CPEPGS---- 103
           D+     +  C +  +        +C C VG    N          DP  CPE  +    
Sbjct: 132 DINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNT 191

Query: 104 -EAYRQLC-PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
              Y   C PG       L       +  DIDEC   E    + TCTNT GS+ CTC  G
Sbjct: 192 VGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT--EMCPINSTCTNTPGSYFCTCHPG 249

Query: 162 WSLAPXXXXXXXXXXXXR--------PDVCGP-GVCRNLPGSYVCLCPEGYVAMPNGSQ 211
           ++ +             R        P  CGP  +C N  GSY C C  G+   P GSQ
Sbjct: 250 FAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 308



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 59/231 (25%), Positives = 76/231 (32%), Gaps = 31/231 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC D   C +     Y  C NT  SY C C   + L S+G   +     RC    +  
Sbjct: 32  GNNCRDSTLCPA-----YATCTNTVDSYYCACKQGF-LSSNGQNHFKDPGVRCKDIDECS 85

Query: 63  SGTETCRDSDELSEDGTMAACCCSVG--AAWGNYCDP-------CPEPGSEAYRQLCP-- 111
              + C  +           C C  G  +  GN   P       C +        +CP  
Sbjct: 86  QSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEH 145

Query: 112 -------GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
                  G       +   S   T  D+DECA       H TC NT G++ C C  G+  
Sbjct: 146 SDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFES 205

Query: 165 APXXXXXXXXXXXXRP-DVCGP-----GVCRNLPGSYVCLCPEGYVAMPNG 209
           +                D C         C N PGSY C C  G+ A  NG
Sbjct: 206 SSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGF-APSNG 255



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 11/83 (13%)

Query: 141 LC-AHGTCTNTFGSFVCTCGAGWSLA--------PXXXXXXXXXXXXRPDVCGP-GVCRN 190
           LC A+ TCTNT  S+ C C  G+  +        P             P  CGP   C+N
Sbjct: 40  LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 99

Query: 191 LPGSYVCLCPEGYVAMPNGSQYL 213
           L G Y C C +G+ + P G+ ++
Sbjct: 100 LSGRYKCSCLDGF-SSPTGNDWV 121


>BC059395-1|AAH59395.1|  821|Homo sapiens EMR1 protein protein.
          Length = 821

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 69/239 (28%), Positives = 89/239 (37%), Gaps = 33/239 (13%)

Query: 2   PGFNCTDVDEC-KSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           PG  C D+DEC +SPQ C     C N  G Y C C   +   +     +   K   +   
Sbjct: 74  PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGND--WVPGKPGNFSCT 131

Query: 60  DLRS--GTETCRDSDELSEDGTMAACCCSVGAAWGN--------YCDP--CPEPGS---- 103
           D+     +  C +  +        +C C VG    N          DP  CPE  +    
Sbjct: 132 DINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNT 191

Query: 104 -EAYRQLC-PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
              Y   C PG       L       +  DIDEC   E    + TCTNT GS+ CTC  G
Sbjct: 192 VGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT--EMCPINSTCTNTPGSYFCTCHPG 249

Query: 162 WSLAPXXXXXXXXXXXXR--------PDVCGP-GVCRNLPGSYVCLCPEGYVAMPNGSQ 211
           ++ +             R        P  CGP  +C N  GSY C C  G+   P GSQ
Sbjct: 250 FAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 308



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 59/231 (25%), Positives = 76/231 (32%), Gaps = 31/231 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC D   C +     Y  C NT  SY C C   + L S+G   +     RC    +  
Sbjct: 32  GNNCRDSTLCPA-----YATCTNTVDSYYCACKQGF-LSSNGQNHFKDPGVRCKDIDECS 85

Query: 63  SGTETCRDSDELSEDGTMAACCCSVG--AAWGNYCDP-------CPEPGSEAYRQLCP-- 111
              + C  +           C C  G  +  GN   P       C +        +CP  
Sbjct: 86  QSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEH 145

Query: 112 -------GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
                  G       +   S   T  D+DECA       H TC NT G++ C C  G+  
Sbjct: 146 SDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFES 205

Query: 165 APXXXXXXXXXXXXRP-DVCGP-----GVCRNLPGSYVCLCPEGYVAMPNG 209
           +                D C         C N PGSY C C  G+ A  NG
Sbjct: 206 SSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGF-APSNG 255



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 11/83 (13%)

Query: 141 LC-AHGTCTNTFGSFVCTCGAGWSLA--------PXXXXXXXXXXXXRPDVCGP-GVCRN 190
           LC A+ TCTNT  S+ C C  G+  +        P             P  CGP   C+N
Sbjct: 40  LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 99

Query: 191 LPGSYVCLCPEGYVAMPNGSQYL 213
           L G Y C C +G+ + P G+ ++
Sbjct: 100 LSGRYKCSCLDGF-SSPTGNDWV 121


>AB065918-1|BAC06133.1|  929|Homo sapiens seven transmembrane helix
           receptor protein.
          Length = 929

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 69/239 (28%), Positives = 89/239 (37%), Gaps = 33/239 (13%)

Query: 2   PGFNCTDVDEC-KSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           PG  C D+DEC +SPQ C     C N  G Y C C   +   +     +   K   +   
Sbjct: 92  PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGND--WVPGKPGNFSCT 149

Query: 60  DLRS--GTETCRDSDELSEDGTMAACCCSVGAAWGN--------YCDP--CPEPGS---- 103
           D+     +  C +  +        +C C VG    N          DP  CPE  +    
Sbjct: 150 DINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNT 209

Query: 104 -EAYRQLC-PGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
              Y   C PG       L       +  DIDEC   E    + TCTNT GS+ CTC  G
Sbjct: 210 VGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT--EMCPINSTCTNTPGSYFCTCHPG 267

Query: 162 WSLAPXXXXXXXXXXXXR--------PDVCGP-GVCRNLPGSYVCLCPEGYVAMPNGSQ 211
           ++ +             R        P  CGP  +C N  GSY C C  G+   P GSQ
Sbjct: 268 FAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 326



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 59/231 (25%), Positives = 76/231 (32%), Gaps = 31/231 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC D   C +     Y  C NT  SY C C   + L S+G   +     RC    +  
Sbjct: 50  GNNCRDSTLCPA-----YATCTNTVDSYYCACKQGF-LSSNGQNHFKDPGVRCKDIDECS 103

Query: 63  SGTETCRDSDELSEDGTMAACCCSVG--AAWGNYCDP-------CPEPGSEAYRQLCP-- 111
              + C  +           C C  G  +  GN   P       C +        +CP  
Sbjct: 104 QSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEH 163

Query: 112 -------GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
                  G       +   S   T  D+DECA       H TC NT G++ C C  G+  
Sbjct: 164 SDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFES 223

Query: 165 APXXXXXXXXXXXXRP-DVCGP-----GVCRNLPGSYVCLCPEGYVAMPNG 209
           +                D C         C N PGSY C C  G+ A  NG
Sbjct: 224 SSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGF-APSNG 273



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 11/83 (13%)

Query: 141 LC-AHGTCTNTFGSFVCTCGAGWSLA--------PXXXXXXXXXXXXRPDVCGP-GVCRN 190
           LC A+ TCTNT  S+ C C  G+  +        P             P  CGP   C+N
Sbjct: 58  LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 117

Query: 191 LPGSYVCLCPEGYVAMPNGSQYL 213
           L G Y C C +G+ + P G+ ++
Sbjct: 118 LSGRYKCSCLDGF-SSPTGNDWV 139


>CR457140-1|CAG33421.1|  448|Homo sapiens FBLN5 protein.
          Length = 448

 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 66/206 (32%), Positives = 85/206 (41%), Gaps = 24/206 (11%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL-- 61
           C DVDEC +    C   Q CINT+G YTC C   Y L+     C D  + R YG      
Sbjct: 125 CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG--QCLDIDECR-YGYCQQLC 181

Query: 62  ----RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQ-LCPGGPGY 116
                S + TC     L+EDG     C  V        +PC +     Y   +C   PGY
Sbjct: 182 ANVPGSYSCTCNPGFTLNEDG---RSCQDVNECATE--NPCVQTCVNTYGSFICRCDPGY 236

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXX 175
           +  LE     V  +D+DEC+  E LC H  C N  G++ C+C  G+ L            
Sbjct: 237 E--LEEDG--VHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINE 291

Query: 176 XXXRPDVCG-PGVCRNLPGSYVCLCP 200
              R   C     C NL G + C+ P
Sbjct: 292 CEHRNHTCNLQQTCYNLQGGFKCIDP 317



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 47/182 (25%), Positives = 69/182 (37%), Gaps = 14/182 (7%)

Query: 36  PNYELVSDGTAC---YDSRKA-RCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAW 91
           PNY  +S    C   Y   ++ +C    +  + +  C  +           C C+ G  W
Sbjct: 102 PNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY-W 160

Query: 92  --GNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV-----TLADIDECAAHEGLCAH 144
                C    E      +QLC   PG       P + +     +  D++ECA  E  C  
Sbjct: 161 LLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQ 219

Query: 145 GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
            TC NT+GSF+C C  G+ L                +      C N PG+Y C CP GY+
Sbjct: 220 -TCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI 278

Query: 205 AM 206
            +
Sbjct: 279 LL 280



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 23/47 (48%), Positives = 28/47 (59%), Gaps = 1/47 (2%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C DV+EC +   C    C+NT GS+ CRC P YEL  DG  C D
Sbjct: 202 GRSCQDVNECATENPCVQ-TCVNTYGSFICRCDPGYELEEDGVHCSD 247



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 22/48 (45%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C+D+DEC  S   CQ+ +C+N  G+Y C CPP Y L+ D  +C D
Sbjct: 242 GVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQD 288



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 49/199 (24%), Positives = 75/199 (37%), Gaps = 24/199 (12%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR-DSDELSEDGTMA 81
           C+ + G+   +C   ++L        D +  +C    + R+  E CR D   ++++G   
Sbjct: 16  CLPSPGNAQAQCTNGFDL--------DRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYL 67

Query: 82  ACCCSVGAAWGNYCDPCPEPGSEAYRQLCP--GGPGYQPVLEPP----SYVVT----LAD 131
               +     G Y +P   P S  Y    P    P Y  +  P      Y +       D
Sbjct: 68  CIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVD 127

Query: 132 IDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           +DECA     C     C NT G + C+C  G+ L              R   C   +C N
Sbjct: 128 VDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDEC---RYGYCQQ-LCAN 183

Query: 191 LPGSYVCLCPEGYVAMPNG 209
           +PGSY C C  G+    +G
Sbjct: 184 VPGSYSCTCNPGFTLNEDG 202



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 53/214 (24%), Positives = 80/214 (37%), Gaps = 21/214 (9%)

Query: 6   CTDVDECKS-PQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVDLR 62
           C D+DEC++ P++C+    C+N  G Y C   P    V  G   Y +  +  Y G     
Sbjct: 40  CLDIDECRTIPEACRGDMMCVNQNGGYLCI--PRTNPVYRGP--YSNPYSTPYSGPYPAA 95

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR----QLCPGGPGYQP 118
           +   +  +   +S       C         N C    E  +++++    Q+C    G   
Sbjct: 96  APPLSAPNYPTISRP---LICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYT 152

Query: 119 VLEPPSYVVT---LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                 Y +      DIDEC    G C    C N  GS+ CTC  G++L           
Sbjct: 153 CSCTDGYWLLEGQCLDIDEC--RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVN 209

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                + C    C N  GS++C C  GY    +G
Sbjct: 210 ECATENPCVQ-TCVNTYGSFICRCDPGYELEEDG 242


>BC022280-1|AAH22280.1|  448|Homo sapiens fibulin 5 protein.
          Length = 448

 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 66/206 (32%), Positives = 85/206 (41%), Gaps = 24/206 (11%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL-- 61
           C DVDEC +    C   Q CINT+G YTC C   Y L+     C D  + R YG      
Sbjct: 125 CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG--QCLDIDECR-YGYCQQLC 181

Query: 62  ----RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQ-LCPGGPGY 116
                S + TC     L+EDG     C  V        +PC +     Y   +C   PGY
Sbjct: 182 ANVPGSYSCTCNPGFTLNEDG---RSCQDVNECATE--NPCVQTCVNTYGSFICRCDPGY 236

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXX 175
           +  LE     V  +D+DEC+  E LC H  C N  G++ C+C  G+ L            
Sbjct: 237 E--LEEDG--VHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINE 291

Query: 176 XXXRPDVCG-PGVCRNLPGSYVCLCP 200
              R   C     C NL G + C+ P
Sbjct: 292 CEHRNHTCNLQQTCYNLQGGFKCIDP 317



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 47/182 (25%), Positives = 69/182 (37%), Gaps = 14/182 (7%)

Query: 36  PNYELVSDGTAC---YDSRKA-RCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAW 91
           PNY  +S    C   Y   ++ +C    +  + +  C  +           C C+ G  W
Sbjct: 102 PNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY-W 160

Query: 92  --GNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV-----TLADIDECAAHEGLCAH 144
                C    E      +QLC   PG       P + +     +  D++ECA  E  C  
Sbjct: 161 LLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQ 219

Query: 145 GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
            TC NT+GSF+C C  G+ L                +      C N PG+Y C CP GY+
Sbjct: 220 -TCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI 278

Query: 205 AM 206
            +
Sbjct: 279 LL 280



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 23/47 (48%), Positives = 28/47 (59%), Gaps = 1/47 (2%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C DV+EC +   C    C+NT GS+ CRC P YEL  DG  C D
Sbjct: 202 GRSCQDVNECATENPCVQ-TCVNTYGSFICRCDPGYELEEDGVHCSD 247



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 22/48 (45%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C+D+DEC  S   CQ+ +C+N  G+Y C CPP Y L+ D  +C D
Sbjct: 242 GVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQD 288



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 49/199 (24%), Positives = 75/199 (37%), Gaps = 24/199 (12%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR-DSDELSEDGTMA 81
           C+ + G+   +C   ++L        D +  +C    + R+  E CR D   ++++G   
Sbjct: 16  CLPSPGNAQAQCTNGFDL--------DRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYL 67

Query: 82  ACCCSVGAAWGNYCDPCPEPGSEAYRQLCP--GGPGYQPVLEPP----SYVVT----LAD 131
               +     G Y +P   P S  Y    P    P Y  +  P      Y +       D
Sbjct: 68  CIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVD 127

Query: 132 IDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           +DECA     C     C NT G + C+C  G+ L              R   C   +C N
Sbjct: 128 VDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDEC---RYGYCQQ-LCAN 183

Query: 191 LPGSYVCLCPEGYVAMPNG 209
           +PGSY C C  G+    +G
Sbjct: 184 VPGSYSCTCNPGFTLNEDG 202



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 53/214 (24%), Positives = 80/214 (37%), Gaps = 21/214 (9%)

Query: 6   CTDVDECKS-PQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVDLR 62
           C D+DEC++ P++C+    C+N  G Y C   P    V  G   Y +  +  Y G     
Sbjct: 40  CLDIDECRTIPEACRGDMMCVNQNGGYLCI--PRTNPVYRGP--YSNPYSTPYSGPYPAA 95

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR----QLCPGGPGYQP 118
           +   +  +   +S       C         N C    E  +++++    Q+C    G   
Sbjct: 96  APPLSAPNYPTISRP---LICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYT 152

Query: 119 VLEPPSYVVT---LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                 Y +      DIDEC    G C    C N  GS+ CTC  G++L           
Sbjct: 153 CSCTDGYWLLEGQCLDIDEC--RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVN 209

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                + C    C N  GS++C C  GY    +G
Sbjct: 210 ECATENPCVQ-TCVNTYGSFICRCDPGYELEEDG 242


>AJ133490-1|CAB38568.1|  448|Homo sapiens fibulin-5 protein.
          Length = 448

 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 66/206 (32%), Positives = 85/206 (41%), Gaps = 24/206 (11%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL-- 61
           C DVDEC +    C   Q CINT+G YTC C   Y L+     C D  + R YG      
Sbjct: 125 CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG--QCLDIDECR-YGYCQQLC 181

Query: 62  ----RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQ-LCPGGPGY 116
                S + TC     L+EDG     C  V        +PC +     Y   +C   PGY
Sbjct: 182 ANVPGSYSCTCNPGFTLNEDG---RSCQDVNECATE--NPCVQTCVNTYGSFICRCDPGY 236

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXX 175
           +  LE     V  +D+DEC+  E LC H  C N  G++ C+C  G+ L            
Sbjct: 237 E--LEEDG--VHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINE 291

Query: 176 XXXRPDVCG-PGVCRNLPGSYVCLCP 200
              R   C     C NL G + C+ P
Sbjct: 292 CEHRNHTCNLQQTCYNLQGGFKCIDP 317



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 47/182 (25%), Positives = 69/182 (37%), Gaps = 14/182 (7%)

Query: 36  PNYELVSDGTAC---YDSRKA-RCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAW 91
           PNY  +S    C   Y   ++ +C    +  + +  C  +           C C+ G  W
Sbjct: 102 PNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY-W 160

Query: 92  --GNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV-----TLADIDECAAHEGLCAH 144
                C    E      +QLC   PG       P + +     +  D++ECA  E  C  
Sbjct: 161 LLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQ 219

Query: 145 GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
            TC NT+GSF+C C  G+ L                +      C N PG+Y C CP GY+
Sbjct: 220 -TCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI 278

Query: 205 AM 206
            +
Sbjct: 279 LL 280



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 23/47 (48%), Positives = 28/47 (59%), Gaps = 1/47 (2%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C DV+EC +   C    C+NT GS+ CRC P YEL  DG  C D
Sbjct: 202 GRSCQDVNECATENPCVQ-TCVNTYGSFICRCDPGYELEEDGVHCSD 247



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 22/48 (45%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C+D+DEC  S   CQ+ +C+N  G+Y C CPP Y L+ D  +C D
Sbjct: 242 GVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQD 288



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 49/199 (24%), Positives = 75/199 (37%), Gaps = 24/199 (12%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR-DSDELSEDGTMA 81
           C+ + G+   +C   ++L        D +  +C    + R+  E CR D   ++++G   
Sbjct: 16  CLPSPGNAQAQCTNGFDL--------DRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYL 67

Query: 82  ACCCSVGAAWGNYCDPCPEPGSEAYRQLCP--GGPGYQPVLEPP----SYVVT----LAD 131
               +     G Y +P   P S  Y    P    P Y  +  P      Y +       D
Sbjct: 68  CIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVD 127

Query: 132 IDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           +DECA     C     C NT G + C+C  G+ L              R   C   +C N
Sbjct: 128 VDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDEC---RYGYCQQ-LCAN 183

Query: 191 LPGSYVCLCPEGYVAMPNG 209
           +PGSY C C  G+    +G
Sbjct: 184 VPGSYSCTCNPGFTLNEDG 202



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 53/214 (24%), Positives = 80/214 (37%), Gaps = 21/214 (9%)

Query: 6   CTDVDECKS-PQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVDLR 62
           C D+DEC++ P++C+    C+N  G Y C   P    V  G   Y +  +  Y G     
Sbjct: 40  CLDIDECRTIPEACRGDMMCVNQNGGYLCI--PRTNPVYRGP--YSNPYSTPYSGPYPAA 95

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR----QLCPGGPGYQP 118
           +   +  +   +S       C         N C    E  +++++    Q+C    G   
Sbjct: 96  APPLSAPNYPTISRP---LICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYT 152

Query: 119 VLEPPSYVVT---LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                 Y +      DIDEC    G C    C N  GS+ CTC  G++L           
Sbjct: 153 CSCTDGYWLLEGQCLDIDEC--RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVN 209

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                + C    C N  GS++C C  GY    +G
Sbjct: 210 ECATENPCVQ-TCVNTYGSFICRCDPGYELEEDG 242


>AF112152-1|AAD41768.1|  448|Homo sapiens developmental arteries and
           neural crest EGF-like protein protein.
          Length = 448

 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 66/206 (32%), Positives = 85/206 (41%), Gaps = 24/206 (11%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL-- 61
           C DVDEC +    C   Q CINT+G YTC C   Y L+     C D  + R YG      
Sbjct: 125 CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG--QCLDIDECR-YGYCQQLC 181

Query: 62  ----RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQ-LCPGGPGY 116
                S + TC     L+EDG     C  V        +PC +     Y   +C   PGY
Sbjct: 182 ANVPGSYSCTCNPGFTLNEDG---RSCQDVNECATE--NPCVQTCVNTYGSFICRCDPGY 236

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXX-XXXXX 175
           +  LE     V  +D+DEC+  E LC H  C N  G++ C+C  G+ L            
Sbjct: 237 E--LEEDG--VHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINE 291

Query: 176 XXXRPDVCG-PGVCRNLPGSYVCLCP 200
              R   C     C NL G + C+ P
Sbjct: 292 CEHRNHTCNLQQTCYNLQGGFKCIDP 317



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 47/182 (25%), Positives = 69/182 (37%), Gaps = 14/182 (7%)

Query: 36  PNYELVSDGTAC---YDSRKA-RCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAW 91
           PNY  +S    C   Y   ++ +C    +  + +  C  +           C C+ G  W
Sbjct: 102 PNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY-W 160

Query: 92  --GNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV-----TLADIDECAAHEGLCAH 144
                C    E      +QLC   PG       P + +     +  D++ECA  E  C  
Sbjct: 161 LLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQ 219

Query: 145 GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
            TC NT+GSF+C C  G+ L                +      C N PG+Y C CP GY+
Sbjct: 220 -TCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI 278

Query: 205 AM 206
            +
Sbjct: 279 LL 280



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 23/47 (48%), Positives = 28/47 (59%), Gaps = 1/47 (2%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C DV+EC +   C    C+NT GS+ CRC P YEL  DG  C D
Sbjct: 202 GRSCQDVNECATENPCVQ-TCVNTYGSFICRCDPGYELEEDGVHCSD 247



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 22/48 (45%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C+D+DEC  S   CQ+ +C+N  G+Y C CPP Y L+ D  +C D
Sbjct: 242 GVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQD 288



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 49/199 (24%), Positives = 75/199 (37%), Gaps = 24/199 (12%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR-DSDELSEDGTMA 81
           C+ + G+   +C   ++L        D +  +C    + R+  E CR D   ++++G   
Sbjct: 16  CLPSPGNAQAQCTNGFDL--------DRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYL 67

Query: 82  ACCCSVGAAWGNYCDPCPEPGSEAYRQLCP--GGPGYQPVLEPP----SYVVT----LAD 131
               +     G Y +P   P S  Y    P    P Y  +  P      Y +       D
Sbjct: 68  CIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVD 127

Query: 132 IDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           +DECA     C     C NT G + C+C  G+ L              R   C   +C N
Sbjct: 128 VDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDEC---RYGYCQQ-LCAN 183

Query: 191 LPGSYVCLCPEGYVAMPNG 209
           +PGSY C C  G+    +G
Sbjct: 184 VPGSYSCTCNPGFTLNEDG 202



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 53/214 (24%), Positives = 80/214 (37%), Gaps = 21/214 (9%)

Query: 6   CTDVDECKS-PQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVDLR 62
           C D+DEC++ P++C+    C+N  G Y C   P    V  G   Y +  +  Y G     
Sbjct: 40  CLDIDECRTIPEACRGDMMCVNQNGGYLCI--PRTNPVYRGP--YSNPYSTPYSGPYPAA 95

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR----QLCPGGPGYQP 118
           +   +  +   +S       C         N C    E  +++++    Q+C    G   
Sbjct: 96  APPLSAPNYPTISRP---LICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYT 152

Query: 119 VLEPPSYVVT---LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                 Y +      DIDEC    G C    C N  GS+ CTC  G++L           
Sbjct: 153 CSCTDGYWLLEGQCLDIDEC--RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVN 209

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                + C    C N  GS++C C  GY    +G
Sbjct: 210 ECATENPCVQ-TCVNTYGSFICRCDPGYELEEDG 242


>AK131562-1|BAD18695.1|  867|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16811 fis, clone THYMU3024602, highly  similar
           to Cell surface glycoprotein EMR1 precursor. ).
          Length = 867

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 66/220 (30%), Positives = 90/220 (40%), Gaps = 47/220 (21%)

Query: 2   PGFNCTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           PG  C D++EC +   C ++  C+N+ GSY+C C   +  +S  + C D           
Sbjct: 74  PGVRCKDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF--ISRNSTCED----------- 120

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
                + C D     E  T   C  +VG    NY   C  PG E+      G   +Q + 
Sbjct: 121 ----VDECADPRACPEHAT---CNNTVG----NYSCFC-NPGFES----SSGHLSFQGLK 164

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR- 179
                  +  DIDEC   E    + TCTNT GS+ CTC  G++ +             R 
Sbjct: 165 ------ASCEDIDECT--EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRD 216

Query: 180 -------PDVCGPG-VCRNLPGSYVCLCPEGYVAMPNGSQ 211
                  P  CGP  +C N  GSY C C  G+   P GSQ
Sbjct: 217 IDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 256


>BC127005-1|AAI27006.1|  823|Homo sapiens egf-like module
           containing, mucin-like, hormone receptor-like 2 protein.
          Length = 823

 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 55/161 (34%), Positives = 71/161 (44%), Gaps = 37/161 (22%)

Query: 6   CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYELV-SDGTACYDSRKARCYGKVDLR 62
           C DVDEC+ +P+ C+ YG C+NT GSYTC+C P ++ +  D   C D          +  
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVN--------ECT 168

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
           SG   C  S     +     C C  G  W       P PGS       P GP    V E 
Sbjct: 169 SGQNPCHSSTHCLNNVGSYQCRCRPG--WQ------PIPGS-------PNGPN-NTVCE- 211

Query: 123 PSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW 162
                   D+DEC++ +  C   T C NT GS+ C C  GW
Sbjct: 212 --------DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244



 Score = 72.9 bits (171), Expect = 8e-13
 Identities = 63/214 (29%), Positives = 81/214 (37%), Gaps = 42/214 (19%)

Query: 2   PGFNCTDVDECK--SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           P   C D++EC   S  SC ++  C NT+GSY C C P YE VS               K
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGA-------------K 107

Query: 59  VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                   TC+D DE  ++  +   C S G             GS      C   PG++ 
Sbjct: 108 TFKNESENTCQDVDECQQNPRL---CKSYGTCVNTL-------GSYT----CQCLPGFKF 153

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
           + E P       D++EC + +  C   T C N  GS+ C C  GW   P           
Sbjct: 154 IPEDPK---VCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 210

Query: 178 XRPDVCGPG--------VCRNLPGSYVCLCPEGY 203
              D C  G        VC N  GSY C C  G+
Sbjct: 211 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 56/192 (29%), Positives = 83/192 (43%), Gaps = 25/192 (13%)

Query: 26  TQGSYTCR--CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAAC 83
           TQ S  C   CP +   V+  TAC  +     + ++ + +  ETC   D+++E  T++  
Sbjct: 23  TQDSRGCARWCPQDSSCVN-ATACRCNPGFSSFSEI-ITTPMETC---DDINECATLSKV 77

Query: 84  CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV----TLADIDECAAHE 139
            C      G + D     GS  Y  +C   PGY+PV    ++      T  D+DEC  + 
Sbjct: 78  SC------GKFSDCWNTEGS--YDCVC--SPGYEPVSGAKTFKNESENTCQDVDECQQNP 127

Query: 140 GLC-AHGTCTNTFGSFVCTCGAGWSLAPX--XXXXXXXXXXXRPDVCGPGV-CRNLPGSY 195
            LC ++GTC NT GS+ C C  G+   P                + C     C N  GSY
Sbjct: 128 RLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSY 187

Query: 196 VCLCPEGYVAMP 207
            C C  G+  +P
Sbjct: 188 QCRCRPGWQPIP 199



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYE 39
           C DVDEC S Q  C     C NT GSY+CRC P ++
Sbjct: 210 CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245


>BC127004-1|AAI27005.1|  823|Homo sapiens egf-like module
           containing, mucin-like, hormone receptor-like 2 protein.
          Length = 823

 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 55/161 (34%), Positives = 71/161 (44%), Gaps = 37/161 (22%)

Query: 6   CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYELV-SDGTACYDSRKARCYGKVDLR 62
           C DVDEC+ +P+ C+ YG C+NT GSYTC+C P ++ +  D   C D          +  
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVN--------ECT 168

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
           SG   C  S     +     C C  G  W       P PGS       P GP    V E 
Sbjct: 169 SGQNPCHSSTHCLNNVGSYQCRCRPG--WQ------PIPGS-------PNGPN-NTVCE- 211

Query: 123 PSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW 162
                   D+DEC++ +  C   T C NT GS+ C C  GW
Sbjct: 212 --------DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244



 Score = 72.9 bits (171), Expect = 8e-13
 Identities = 63/214 (29%), Positives = 81/214 (37%), Gaps = 42/214 (19%)

Query: 2   PGFNCTDVDECK--SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           P   C D++EC   S  SC ++  C NT+GSY C C P YE VS               K
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGA-------------K 107

Query: 59  VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                   TC+D DE  ++  +   C S G             GS      C   PG++ 
Sbjct: 108 TFKNESENTCQDVDECQQNPRL---CKSYGTCVNTL-------GSYT----CQCLPGFKF 153

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
           + E P       D++EC + +  C   T C N  GS+ C C  GW   P           
Sbjct: 154 IPEDPK---VCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 210

Query: 178 XRPDVCGPG--------VCRNLPGSYVCLCPEGY 203
              D C  G        VC N  GSY C C  G+
Sbjct: 211 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 56/192 (29%), Positives = 83/192 (43%), Gaps = 25/192 (13%)

Query: 26  TQGSYTCR--CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAAC 83
           TQ S  C   CP +   V+  TAC  +     + ++ + +  ETC   D+++E  T++  
Sbjct: 23  TQDSRGCARWCPQDSSCVN-ATACRCNPGFSSFSEI-ITTPMETC---DDINECATLSKV 77

Query: 84  CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV----TLADIDECAAHE 139
            C      G + D     GS  Y  +C   PGY+PV    ++      T  D+DEC  + 
Sbjct: 78  SC------GKFSDCWNTEGS--YDCVC--SPGYEPVSGAKTFKNESENTCQDVDECQQNP 127

Query: 140 GLC-AHGTCTNTFGSFVCTCGAGWSLAPX--XXXXXXXXXXXRPDVCGPGV-CRNLPGSY 195
            LC ++GTC NT GS+ C C  G+   P                + C     C N  GSY
Sbjct: 128 RLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSY 187

Query: 196 VCLCPEGYVAMP 207
            C C  G+  +P
Sbjct: 188 QCRCRPGWQPIP 199



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYE 39
           C DVDEC S Q  C     C NT GSY+CRC P ++
Sbjct: 210 CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245


>AC005327-1|AAC27673.1|  287|Homo sapiens CD97_HUMAN, partial CDS
           protein.
          Length = 287

 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 49/168 (29%), Positives = 69/168 (41%), Gaps = 13/168 (7%)

Query: 8   DVDECK--SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           D++EC   S  SC ++  C NT+GSY C C P YE VS      +  +  C    + +  
Sbjct: 59  DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 118

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPG---SEAYRQLCPGGPGYQ 117
              C+             C C  G    N C    +PC       +      C   PG+Q
Sbjct: 119 PRLCKSYGTCVNTLGSYTCQCLPGFKDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 178

Query: 118 PVLEPPS--YVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW 162
           P+   P+        D+DEC++ +  C   T C NT GS+ C C  GW
Sbjct: 179 PIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 226



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 34/104 (32%), Positives = 44/104 (42%), Gaps = 14/104 (13%)

Query: 110 CPGGPGYQPVLEPPSYVV----TLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSL 164
           C   PGY+PV    ++      T  D+DEC  +  LC ++GTC NT GS+ C C      
Sbjct: 86  CVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQC------ 139

Query: 165 APXXXXXXXXXXXXRPDVCGPGV-CRNLPGSYVCLCPEGYVAMP 207
            P             P  C     C N  GSY C C  G+  +P
Sbjct: 140 LPGFKDVNECTSGQNP--CHSSTHCLNNVGSYQCRCRPGWQPIP 181



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYE 39
           C DVDEC S Q  C     C NT GSY+CRC P ++
Sbjct: 192 CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 227


>AK222891-1|BAD96611.1|  810|Homo sapiens egf-like module
           containing, mucin-like, hormone receptor-like sequence 2
           isofor protein.
          Length = 810

 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 56/161 (34%), Positives = 71/161 (44%), Gaps = 37/161 (22%)

Query: 6   CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYEL-VSDGTACYDSRKARCYGKVDLR 62
           C DVDEC+ +P+ C+ YG C+NT GSYTC+C P ++L   D   C D          +  
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVN--------ECT 168

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
           SG   C  S     +     C C  G  W       P PGS       P GP    V E 
Sbjct: 169 SGQNPCHSSTHCLNNVGSYQCRCRPG--WQ------PIPGS-------PNGPN-NTVCE- 211

Query: 123 PSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW 162
                   D+DEC++ +  C   T C NT GS+ C C  GW
Sbjct: 212 --------DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 63/214 (29%), Positives = 80/214 (37%), Gaps = 42/214 (19%)

Query: 2   PGFNCTDVDECK--SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           P   C D++EC   S  SC ++  C NT+GSY C C P YE VS               K
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGA-------------K 107

Query: 59  VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                   TC+D DE  ++  +   C S G             GS      C   PG++ 
Sbjct: 108 TFKNESENTCQDVDECQQNPRL---CKSYGTCVNTL-------GSYT----CQCLPGFKL 153

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
             E P       D++EC + +  C   T C N  GS+ C C  GW   P           
Sbjct: 154 KPEDPKLCT---DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 210

Query: 178 XRPDVCGPG--------VCRNLPGSYVCLCPEGY 203
              D C  G        VC N  GSY C C  G+
Sbjct: 211 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 57/192 (29%), Positives = 84/192 (43%), Gaps = 25/192 (13%)

Query: 26  TQGSYTCR--CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAAC 83
           TQ S  C   CP +   V+  TAC  +     + ++ + +  ETC   D+++E  T++  
Sbjct: 23  TQDSRGCARWCPQDSSCVN-ATACRCNPGFSSFSEI-ITTPMETC---DDINECATLSKV 77

Query: 84  CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV----TLADIDECAAHE 139
            C      G + D     GS  Y  +C   PGY+PV    ++      T  D+DEC  + 
Sbjct: 78  SC------GKFSDCWNTEGS--YDCVC--SPGYEPVSGAKTFKNESENTCQDVDECQQNP 127

Query: 140 GLC-AHGTCTNTFGSFVCTCGAGWSLAPX--XXXXXXXXXXXRPDVCGPGV-CRNLPGSY 195
            LC ++GTC NT GS+ C C  G+ L P                + C     C N  GSY
Sbjct: 128 RLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSY 187

Query: 196 VCLCPEGYVAMP 207
            C C  G+  +P
Sbjct: 188 QCRCRPGWQPIP 199



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYE 39
           C DVDEC S Q  C     C NT GSY+CRC P ++
Sbjct: 210 CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245


>AF114491-1|AAF21974.1|  823|Homo sapiens EGF-like module EMR2
           protein.
          Length = 823

 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 56/161 (34%), Positives = 71/161 (44%), Gaps = 37/161 (22%)

Query: 6   CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYEL-VSDGTACYDSRKARCYGKVDLR 62
           C DVDEC+ +P+ C+ YG C+NT GSYTC+C P ++L   D   C D          +  
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVN--------ECT 168

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
           SG   C  S     +     C C  G  W       P PGS       P GP    V E 
Sbjct: 169 SGQNPCHSSTHCLNNVGSYQCRCRPG--WQ------PIPGS-------PNGPN-NTVCE- 211

Query: 123 PSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW 162
                   D+DEC++ +  C   T C NT GS+ C C  GW
Sbjct: 212 --------DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 63/214 (29%), Positives = 80/214 (37%), Gaps = 42/214 (19%)

Query: 2   PGFNCTDVDECK--SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           P   C D++EC   S  SC ++  C NT+GSY C C P YE VS               K
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGA-------------K 107

Query: 59  VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                   TC+D DE  ++  +   C S G             GS      C   PG++ 
Sbjct: 108 TFKNESENTCQDVDECQQNPRL---CKSYGTCVNTL-------GSYT----CQCLPGFKL 153

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
             E P       D++EC + +  C   T C N  GS+ C C  GW   P           
Sbjct: 154 KPEDPKLCT---DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 210

Query: 178 XRPDVCGPG--------VCRNLPGSYVCLCPEGY 203
              D C  G        VC N  GSY C C  G+
Sbjct: 211 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 57/192 (29%), Positives = 84/192 (43%), Gaps = 25/192 (13%)

Query: 26  TQGSYTCR--CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAAC 83
           TQ S  C   CP +   V+  TAC  +     + ++ + +  ETC   D+++E  T++  
Sbjct: 23  TQDSRGCARWCPQDSSCVN-ATACRCNPGFSSFSEI-ITTPMETC---DDINECATLSKV 77

Query: 84  CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV----TLADIDECAAHE 139
            C      G + D     GS  Y  +C   PGY+PV    ++      T  D+DEC  + 
Sbjct: 78  SC------GKFSDCWNTEGS--YDCVC--SPGYEPVSGAKTFKNESENTCQDVDECQQNP 127

Query: 140 GLC-AHGTCTNTFGSFVCTCGAGWSLAPX--XXXXXXXXXXXRPDVCGPGV-CRNLPGSY 195
            LC ++GTC NT GS+ C C  G+ L P                + C     C N  GSY
Sbjct: 128 RLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSY 187

Query: 196 VCLCPEGYVAMP 207
            C C  G+  +P
Sbjct: 188 QCRCRPGWQPIP 199



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYE 39
           C DVDEC S Q  C     C NT GSY+CRC P ++
Sbjct: 210 CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245


>AB065931-1|BAC06146.1|  837|Homo sapiens seven transmembrane helix
           receptor protein.
          Length = 837

 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 56/161 (34%), Positives = 71/161 (44%), Gaps = 37/161 (22%)

Query: 6   CTDVDECK-SPQSCQ-YGQCINTQGSYTCRCPPNYEL-VSDGTACYDSRKARCYGKVDLR 62
           C DVDEC+ +P+ C+ YG C+NT GSYTC+C P ++L   D   C D          +  
Sbjct: 118 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVN--------ECT 169

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
           SG   C  S     +     C C  G  W       P PGS       P GP    V E 
Sbjct: 170 SGQNPCHSSTHCLNNVGSYQCRCRPG--WQ------PIPGS-------PNGPN-NTVCE- 212

Query: 123 PSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGW 162
                   D+DEC++ +  C   T C NT GS+ C C  GW
Sbjct: 213 --------DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 245



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 63/214 (29%), Positives = 80/214 (37%), Gaps = 42/214 (19%)

Query: 2   PGFNCTDVDECK--SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           P   C D++EC   S  SC ++  C NT+GSY C C P YE VS               K
Sbjct: 62  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGA-------------K 108

Query: 59  VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                   TC+D DE  ++  +   C S G             GS      C   PG++ 
Sbjct: 109 TFKNESENTCQDVDECQQNPRL---CKSYGTCVNTL-------GSYT----CQCLPGFKL 154

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
             E P       D++EC + +  C   T C N  GS+ C C  GW   P           
Sbjct: 155 KPEDPKLCT---DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 211

Query: 178 XRPDVCGPG--------VCRNLPGSYVCLCPEGY 203
              D C  G        VC N  GSY C C  G+
Sbjct: 212 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 245



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 57/192 (29%), Positives = 84/192 (43%), Gaps = 25/192 (13%)

Query: 26  TQGSYTCR--CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAAC 83
           TQ S  C   CP +   V+  TAC  +     + ++ + +  ETC   D+++E  T++  
Sbjct: 24  TQDSRGCARWCPQDSSCVN-ATACRCNPGFSSFSEI-ITTPMETC---DDINECATLSKV 78

Query: 84  CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV----TLADIDECAAHE 139
            C      G + D     GS  Y  +C   PGY+PV    ++      T  D+DEC  + 
Sbjct: 79  SC------GKFSDCWNTEGS--YDCVC--SPGYEPVSGAKTFKNESENTCQDVDECQQNP 128

Query: 140 GLC-AHGTCTNTFGSFVCTCGAGWSLAPX--XXXXXXXXXXXRPDVCGPGV-CRNLPGSY 195
            LC ++GTC NT GS+ C C  G+ L P                + C     C N  GSY
Sbjct: 129 RLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSY 188

Query: 196 VCLCPEGYVAMP 207
            C C  G+  +P
Sbjct: 189 QCRCRPGWQPIP 200



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYE 39
           C DVDEC S Q  C     C NT GSY+CRC P ++
Sbjct: 211 CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 246


>X53743-1|CAA37772.1|  683|Homo sapiens fibulin-1 C protein.
          Length = 683

 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 68/221 (30%), Positives = 91/221 (41%), Gaps = 31/221 (14%)

Query: 3   GFNCTDVDECKSP-QSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKV 59
           G  C DVDEC  P + C  G +C+N+ GS+ C C   Y        C D  + + Y G++
Sbjct: 351 GTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL 410

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPGGPG- 115
                   C    E +    +  C CSVG   +  G  C+   E  S    Q C    G 
Sbjct: 411 --------CGHKCENTLGSYL--CSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGS 460

Query: 116 YQPVLEPPSYV-----VTLADIDECAAHEG--LCAHGTCTNTFGSFVCTC-GAGWSLAPX 167
           YQ        +     VT  DIDECA   G  +C++  C N  GSF C+C  +G+ LAP 
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPN 519

Query: 168 XXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGY 203
                           C     C N+ G++ CL   CPE Y
Sbjct: 520 GRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 23/214 (10%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C+    C+  QC +T     C C   Y+L+SDG +C D  +    G    R G E+C 
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC-ITGSHSCRLG-ESCI 234

Query: 70  DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG---YQPVLEP 122
           ++         ++C         N C    E  S  +  L    C    G    +P L+ 
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294

Query: 123 PSYVVTLA-----DIDECAAHEGLCAHG-TCTNTFGSFVC-----TCGAGWSLAPXXXXX 171
            S  +  A     DI+EC +    C  G TC NT GS+ C      CG G+ L       
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354

Query: 172 XXXXXXXRP-DVCGPG-VCRNLPGSYVCLCPEGY 203
                   P + CG G  C N PGS+ C C  GY
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 68/227 (29%), Positives = 89/227 (39%), Gaps = 33/227 (14%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SR 51
           G +C DV+EC     SC+ G+ CINT GS+ C+    C   YEL  D  +C D     S 
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESG 269

Query: 52  KARCYGKVDLRS--GTETCRDSDELSEDGTMAAC--CCSVGAAWGNYCDPCP-------E 100
              C      ++  G+  CR   +        A   C  +     +   PCP        
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECL-SISAPCPIGHTCINT 328

Query: 101 PGSEAYRQLCPG-GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTC 158
            GS   ++  P  G GY    E    V    D+DECA     C  G  C N+ GSF C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCV----DVDECAPPAEPCGKGHRCVNSPGSFRCEC 384

Query: 159 GAGWSLAPXXXXXXXXXXXXR-PD-VCGPGVCRNLPGSYVCLCPEGY 203
             G+                R P  +CG   C N  GSY+C C  G+
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGF 430



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 64/225 (28%), Positives = 91/225 (40%), Gaps = 40/225 (17%)

Query: 5   NCTDVDECKSP-QSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SRKA 53
           +C D+DEC+S   +C     C NT GS+ CR    C   +   + G  C D     S  A
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISA 317

Query: 54  RC---------YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE 104
            C          G    +     C     L+E+GT    C  V     + C P  EP  +
Sbjct: 318 PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR---CVDV-----DECAPPAEPCGK 369

Query: 105 AYRQLCPGGPG-YQPVLEPPSYVVTLA----DIDECAAHEG-LCAHGTCTNTFGSFVCTC 158
            +R  C   PG ++   +   Y   ++    D++EC  + G LC H  C NT GS++C+C
Sbjct: 370 GHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSC 426

Query: 159 GAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G+ L+                 C    C N+ GSY C C  GY
Sbjct: 427 SVGFRLS-VDGRSCEDINECSSSPCSQ-ECANVYGSYQCYCRRGY 469



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
           C + G E    +C    GYQ + +     V+  D++EC      C  G +C NT GSF C
Sbjct: 190 CRDTGDEV---VCSCFVGYQLLSDG----VSCEDVNECITGSHSCRLGESCINTVGSFRC 242

Query: 157 ----TCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVC----LCPEGYV 204
               +CG G+ L                  C P  +C+N  GS+ C     C  G++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299


>X53742-1|CAA37771.1|  601|Homo sapiens fibulin-1 B protein.
          Length = 601

 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 68/221 (30%), Positives = 91/221 (41%), Gaps = 31/221 (14%)

Query: 3   GFNCTDVDECKSP-QSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKV 59
           G  C DVDEC  P + C  G +C+N+ GS+ C C   Y        C D  + + Y G++
Sbjct: 351 GTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL 410

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPGGPG- 115
                   C    E +    +  C CSVG   +  G  C+   E  S    Q C    G 
Sbjct: 411 --------CGHKCENTLGSYL--CSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGS 460

Query: 116 YQPVLEPPSYV-----VTLADIDECAAHEG--LCAHGTCTNTFGSFVCTC-GAGWSLAPX 167
           YQ        +     VT  DIDECA   G  +C++  C N  GSF C+C  +G+ LAP 
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPN 519

Query: 168 XXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGY 203
                           C     C N+ G++ CL   CPE Y
Sbjct: 520 GRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 23/214 (10%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C+    C+  QC +T     C C   Y+L+SDG +C D  +    G    R G E+C 
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC-ITGSHSCRLG-ESCI 234

Query: 70  DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG---YQPVLEP 122
           ++         ++C         N C    E  S  +  L    C    G    +P L+ 
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294

Query: 123 PSYVVTLA-----DIDECAAHEGLCAHG-TCTNTFGSFVC-----TCGAGWSLAPXXXXX 171
            S  +  A     DI+EC +    C  G TC NT GS+ C      CG G+ L       
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354

Query: 172 XXXXXXXRP-DVCGPG-VCRNLPGSYVCLCPEGY 203
                   P + CG G  C N PGS+ C C  GY
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 68/227 (29%), Positives = 89/227 (39%), Gaps = 33/227 (14%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SR 51
           G +C DV+EC     SC+ G+ CINT GS+ C+    C   YEL  D  +C D     S 
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESG 269

Query: 52  KARCYGKVDLRS--GTETCRDSDELSEDGTMAAC--CCSVGAAWGNYCDPCP-------E 100
              C      ++  G+  CR   +        A   C  +     +   PCP        
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECL-SISAPCPIGHTCINT 328

Query: 101 PGSEAYRQLCPG-GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTC 158
            GS   ++  P  G GY    E    V    D+DECA     C  G  C N+ GSF C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCV----DVDECAPPAEPCGKGHRCVNSPGSFRCEC 384

Query: 159 GAGWSLAPXXXXXXXXXXXXR-PD-VCGPGVCRNLPGSYVCLCPEGY 203
             G+                R P  +CG   C N  GSY+C C  G+
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGF 430



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 64/225 (28%), Positives = 91/225 (40%), Gaps = 40/225 (17%)

Query: 5   NCTDVDECKSP-QSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SRKA 53
           +C D+DEC+S   +C     C NT GS+ CR    C   +   + G  C D     S  A
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISA 317

Query: 54  RC---------YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE 104
            C          G    +     C     L+E+GT    C  V     + C P  EP  +
Sbjct: 318 PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR---CVDV-----DECAPPAEPCGK 369

Query: 105 AYRQLCPGGPG-YQPVLEPPSYVVTLA----DIDECAAHEG-LCAHGTCTNTFGSFVCTC 158
            +R  C   PG ++   +   Y   ++    D++EC  + G LC H  C NT GS++C+C
Sbjct: 370 GHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSC 426

Query: 159 GAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G+ L+                 C    C N+ GSY C C  GY
Sbjct: 427 SVGFRLS-VDGRSCEDINECSSSPCSQ-ECANVYGSYQCYCRRGY 469



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
           C + G E    +C    GYQ + +     V+  D++EC      C  G +C NT GSF C
Sbjct: 190 CRDTGDEV---VCSCFVGYQLLSDG----VSCEDVNECITGSHSCRLGESCINTVGSFRC 242

Query: 157 ----TCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVC----LCPEGYV 204
               +CG G+ L                  C P  +C+N  GS+ C     C  G++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299


>X53741-1|CAA37770.1|  566|Homo sapiens fibulin-1 A protein.
          Length = 566

 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 68/221 (30%), Positives = 91/221 (41%), Gaps = 31/221 (14%)

Query: 3   GFNCTDVDECKSP-QSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKV 59
           G  C DVDEC  P + C  G +C+N+ GS+ C C   Y        C D  + + Y G++
Sbjct: 351 GTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL 410

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPGGPG- 115
                   C    E +    +  C CSVG   +  G  C+   E  S    Q C    G 
Sbjct: 411 --------CGHKCENTLGSYL--CSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGS 460

Query: 116 YQPVLEPPSYV-----VTLADIDECAAHEG--LCAHGTCTNTFGSFVCTC-GAGWSLAPX 167
           YQ        +     VT  DIDECA   G  +C++  C N  GSF C+C  +G+ LAP 
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPN 519

Query: 168 XXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGY 203
                           C     C N+ G++ CL   CPE Y
Sbjct: 520 GRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 23/214 (10%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C+    C+  QC +T     C C   Y+L+SDG +C D  +    G    R G E+C 
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC-ITGSHSCRLG-ESCI 234

Query: 70  DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG---YQPVLEP 122
           ++         ++C         N C    E  S  +  L    C    G    +P L+ 
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294

Query: 123 PSYVVTLA-----DIDECAAHEGLCAHG-TCTNTFGSFVC-----TCGAGWSLAPXXXXX 171
            S  +  A     DI+EC +    C  G TC NT GS+ C      CG G+ L       
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354

Query: 172 XXXXXXXRP-DVCGPG-VCRNLPGSYVCLCPEGY 203
                   P + CG G  C N PGS+ C C  GY
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 68/227 (29%), Positives = 89/227 (39%), Gaps = 33/227 (14%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SR 51
           G +C DV+EC     SC+ G+ CINT GS+ C+    C   YEL  D  +C D     S 
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESG 269

Query: 52  KARCYGKVDLRS--GTETCRDSDELSEDGTMAAC--CCSVGAAWGNYCDPCP-------E 100
              C      ++  G+  CR   +        A   C  +     +   PCP        
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECL-SISAPCPIGHTCINT 328

Query: 101 PGSEAYRQLCPG-GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTC 158
            GS   ++  P  G GY    E    V    D+DECA     C  G  C N+ GSF C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCV----DVDECAPPAEPCGKGHRCVNSPGSFRCEC 384

Query: 159 GAGWSLAPXXXXXXXXXXXXR-PD-VCGPGVCRNLPGSYVCLCPEGY 203
             G+                R P  +CG   C N  GSY+C C  G+
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGF 430



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 64/225 (28%), Positives = 91/225 (40%), Gaps = 40/225 (17%)

Query: 5   NCTDVDECKSP-QSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SRKA 53
           +C D+DEC+S   +C     C NT GS+ CR    C   +   + G  C D     S  A
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISA 317

Query: 54  RC---------YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE 104
            C          G    +     C     L+E+GT    C  V     + C P  EP  +
Sbjct: 318 PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR---CVDV-----DECAPPAEPCGK 369

Query: 105 AYRQLCPGGPG-YQPVLEPPSYVVTLA----DIDECAAHEG-LCAHGTCTNTFGSFVCTC 158
            +R  C   PG ++   +   Y   ++    D++EC  + G LC H  C NT GS++C+C
Sbjct: 370 GHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSC 426

Query: 159 GAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G+ L+                 C    C N+ GSY C C  GY
Sbjct: 427 SVGFRLS-VDGRSCEDINECSSSPCSQ-ECANVYGSYQCYCRRGY 469



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
           C + G E    +C    GYQ + +     V+  D++EC      C  G +C NT GSF C
Sbjct: 190 CRDTGDEV---VCSCFVGYQLLSDG----VSCEDVNECITGSHSCRLGESCINTVGSFRC 242

Query: 157 ----TCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVC----LCPEGYV 204
               +CG G+ L                  C P  +C+N  GS+ C     C  G++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299


>U01244-1|AAB17099.1|  703|Homo sapiens fibulin-1D protein.
          Length = 703

 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 68/221 (30%), Positives = 91/221 (41%), Gaps = 31/221 (14%)

Query: 3   GFNCTDVDECKSP-QSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKV 59
           G  C DVDEC  P + C  G +C+N+ GS+ C C   Y        C D  + + Y G++
Sbjct: 351 GTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL 410

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPGGPG- 115
                   C    E +    +  C CSVG   +  G  C+   E  S    Q C    G 
Sbjct: 411 --------CGHKCENTLGSYL--CSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGS 460

Query: 116 YQPVLEPPSYV-----VTLADIDECAAHEG--LCAHGTCTNTFGSFVCTC-GAGWSLAPX 167
           YQ        +     VT  DIDECA   G  +C++  C N  GSF C+C  +G+ LAP 
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPN 519

Query: 168 XXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGY 203
                           C     C N+ G++ CL   CPE Y
Sbjct: 520 GRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 23/214 (10%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C+    C+  QC +T     C C   Y+L+SDG +C D  +    G    R G E+C 
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC-ITGSHSCRLG-ESCI 234

Query: 70  DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG---YQPVLEP 122
           ++         ++C         N C    E  S  +  L    C    G    +P L+ 
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294

Query: 123 PSYVVTLA-----DIDECAAHEGLCAHG-TCTNTFGSFVC-----TCGAGWSLAPXXXXX 171
            S  +  A     DI+EC +    C  G TC NT GS+ C      CG G+ L       
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354

Query: 172 XXXXXXXRP-DVCGPG-VCRNLPGSYVCLCPEGY 203
                   P + CG G  C N PGS+ C C  GY
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 68/227 (29%), Positives = 89/227 (39%), Gaps = 33/227 (14%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SR 51
           G +C DV+EC     SC+ G+ CINT GS+ C+    C   YEL  D  +C D     S 
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESG 269

Query: 52  KARCYGKVDLRS--GTETCRDSDELSEDGTMAAC--CCSVGAAWGNYCDPCP-------E 100
              C      ++  G+  CR   +        A   C  +     +   PCP        
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECL-SISAPCPIGHTCINT 328

Query: 101 PGSEAYRQLCPG-GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTC 158
            GS   ++  P  G GY    E    V    D+DECA     C  G  C N+ GSF C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCV----DVDECAPPAEPCGKGHRCVNSPGSFRCEC 384

Query: 159 GAGWSLAPXXXXXXXXXXXXR-PD-VCGPGVCRNLPGSYVCLCPEGY 203
             G+                R P  +CG   C N  GSY+C C  G+
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGF 430



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 64/225 (28%), Positives = 91/225 (40%), Gaps = 40/225 (17%)

Query: 5   NCTDVDECKSP-QSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SRKA 53
           +C D+DEC+S   +C     C NT GS+ CR    C   +   + G  C D     S  A
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISA 317

Query: 54  RC---------YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE 104
            C          G    +     C     L+E+GT    C  V     + C P  EP  +
Sbjct: 318 PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR---CVDV-----DECAPPAEPCGK 369

Query: 105 AYRQLCPGGPG-YQPVLEPPSYVVTLA----DIDECAAHEG-LCAHGTCTNTFGSFVCTC 158
            +R  C   PG ++   +   Y   ++    D++EC  + G LC H  C NT GS++C+C
Sbjct: 370 GHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSC 426

Query: 159 GAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G+ L+                 C    C N+ GSY C C  GY
Sbjct: 427 SVGFRLS-VDGRSCEDINECSSSPCSQ-ECANVYGSYQCYCRRGY 469



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
           C + G E    +C    GYQ + +     V+  D++EC      C  G +C NT GSF C
Sbjct: 190 CRDTGDEV---VCSCFVGYQLLSDG----VSCEDVNECITGSHSCRLGESCINTVGSFRC 242

Query: 157 ----TCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVC----LCPEGYV 204
               +CG G+ L                  C P  +C+N  GS+ C     C  G++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299


>BC022497-1|AAH22497.1|  683|Homo sapiens fibulin 1 protein.
          Length = 683

 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 68/221 (30%), Positives = 90/221 (40%), Gaps = 31/221 (14%)

Query: 3   GFNCTDVDECKSP-QSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKV 59
           G  C DVDEC  P + C  G +C+N+ GS+ C C   Y        C D  + + Y G++
Sbjct: 351 GTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL 410

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPGGPG- 115
                   C    E +    +  C CSVG   +  G  C+   E  S    Q C    G 
Sbjct: 411 --------CGHKCENTLGSYL--CSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGS 460

Query: 116 YQPVLEPPSYV-----VTLADIDECAAHEG--LCAHGTCTNTFGSFVCTC-GAGWSLAPX 167
           YQ        +     VT  DIDECA   G  +C++  C N  GSF C+C  +G+ LAP 
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPN 519

Query: 168 XXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGY 203
                           C     C N+ G + CL   CPE Y
Sbjct: 520 GSNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 23/214 (10%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C+    C+  QC +T     C C   Y+L+SDG +C D  +    G    R G E+C 
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC-ITGSHSCRLG-ESCI 234

Query: 70  DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG---YQPVLEP 122
           ++         ++C         N C    E  S  +  L    C    G    +P L+ 
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294

Query: 123 PSYVVTLA-----DIDECAAHEGLCAHG-TCTNTFGSFVC-----TCGAGWSLAPXXXXX 171
            S  +  A     DI+EC +    C  G TC NT GS+ C      CG G+ L       
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354

Query: 172 XXXXXXXRP-DVCGPG-VCRNLPGSYVCLCPEGY 203
                   P + CG G  C N PGS+ C C  GY
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 68/227 (29%), Positives = 89/227 (39%), Gaps = 33/227 (14%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SR 51
           G +C DV+EC     SC+ G+ CINT GS+ C+    C   YEL  D  +C D     S 
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESG 269

Query: 52  KARCYGKVDLRS--GTETCRDSDELSEDGTMAAC--CCSVGAAWGNYCDPCP-------E 100
              C      ++  G+  CR   +        A   C  +     +   PCP        
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECL-SISAPCPIGHTCINT 328

Query: 101 PGSEAYRQLCPG-GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTC 158
            GS   ++  P  G GY    E    V    D+DECA     C  G  C N+ GSF C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCV----DVDECAPPAEPCGKGHRCVNSPGSFRCEC 384

Query: 159 GAGWSLAPXXXXXXXXXXXXR-PD-VCGPGVCRNLPGSYVCLCPEGY 203
             G+                R P  +CG   C N  GSY+C C  G+
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGF 430



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 64/225 (28%), Positives = 91/225 (40%), Gaps = 40/225 (17%)

Query: 5   NCTDVDECKSP-QSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SRKA 53
           +C D+DEC+S   +C     C NT GS+ CR    C   +   + G  C D     S  A
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISA 317

Query: 54  RC---------YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE 104
            C          G    +     C     L+E+GT    C  V     + C P  EP  +
Sbjct: 318 PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR---CVDV-----DECAPPAEPCGK 369

Query: 105 AYRQLCPGGPG-YQPVLEPPSYVVTLA----DIDECAAHEG-LCAHGTCTNTFGSFVCTC 158
            +R  C   PG ++   +   Y   ++    D++EC  + G LC H  C NT GS++C+C
Sbjct: 370 GHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSC 426

Query: 159 GAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G+ L+                 C    C N+ GSY C C  GY
Sbjct: 427 SVGFRLS-VDGRSCEDINECSSSPCSQ-ECANVYGSYQCYCRRGY 469



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
           C + G E    +C    GYQ + +     V+  D++EC      C  G +C NT GSF C
Sbjct: 190 CRDTGDEV---VCSCFVGYQLLSDG----VSCEDVNECITGSHSCRLGESCINTVGSFRC 242

Query: 157 ----TCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVC----LCPEGYV 204
               +CG G+ L                  C P  +C+N  GS+ C     C  G++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299


>AF126110-1|AAK37822.1|  703|Homo sapiens fibulin-1 isoform D
           precursor protein.
          Length = 703

 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 68/221 (30%), Positives = 91/221 (41%), Gaps = 31/221 (14%)

Query: 3   GFNCTDVDECKSP-QSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKV 59
           G  C DVDEC  P + C  G +C+N+ GS+ C C   Y        C D  + + Y G++
Sbjct: 351 GTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL 410

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPGGPG- 115
                   C    E +    +  C CSVG   +  G  C+   E  S    Q C    G 
Sbjct: 411 --------CGHKCENTLGSYL--CSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGS 460

Query: 116 YQPVLEPPSYV-----VTLADIDECAAHEG--LCAHGTCTNTFGSFVCTC-GAGWSLAPX 167
           YQ        +     VT  DIDECA   G  +C++  C N  GSF C+C  +G+ LAP 
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPN 519

Query: 168 XXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGY 203
                           C     C N+ G++ CL   CPE Y
Sbjct: 520 GRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENY 560



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 23/214 (10%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C+    C+  QC +T     C C   Y+L+SDG +C D  +    G    R G E+C 
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC-ITGSHSCRLG-ESCI 234

Query: 70  DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG---YQPVLEP 122
           ++         ++C         N C    E  S  +  L    C    G    +P L+ 
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294

Query: 123 PSYVVTLA-----DIDECAAHEGLCAHG-TCTNTFGSFVC-----TCGAGWSLAPXXXXX 171
            S  +  A     DI+EC +    C  G TC NT GS+ C      CG G+ L       
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354

Query: 172 XXXXXXXRP-DVCGPG-VCRNLPGSYVCLCPEGY 203
                   P + CG G  C N PGS+ C C  GY
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 68/227 (29%), Positives = 89/227 (39%), Gaps = 33/227 (14%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SR 51
           G +C DV+EC     SC+ G+ CINT GS+ C+    C   YEL  D  +C D     S 
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESG 269

Query: 52  KARCYGKVDLRS--GTETCRDSDELSEDGTMAAC--CCSVGAAWGNYCDPCP-------E 100
              C      ++  G+  CR   +        A   C  +     +   PCP        
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECL-SISAPCPIGHTCINT 328

Query: 101 PGSEAYRQLCPG-GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTC 158
            GS   ++  P  G GY    E    V    D+DECA     C  G  C N+ GSF C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCV----DVDECAPPAEPCGKGHRCVNSPGSFRCEC 384

Query: 159 GAGWSLAPXXXXXXXXXXXXR-PD-VCGPGVCRNLPGSYVCLCPEGY 203
             G+                R P  +CG   C N  GSY+C C  G+
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGF 430



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 64/225 (28%), Positives = 91/225 (40%), Gaps = 40/225 (17%)

Query: 5   NCTDVDECKSP-QSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SRKA 53
           +C D+DEC+S   +C     C NT GS+ CR    C   +   + G  C D     S  A
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISA 317

Query: 54  RC---------YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE 104
            C          G    +     C     L+E+GT    C  V     + C P  EP  +
Sbjct: 318 PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR---CVDV-----DECAPPAEPCGK 369

Query: 105 AYRQLCPGGPG-YQPVLEPPSYVVTLA----DIDECAAHEG-LCAHGTCTNTFGSFVCTC 158
            +R  C   PG ++   +   Y   ++    D++EC  + G LC H  C NT GS++C+C
Sbjct: 370 GHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSC 426

Query: 159 GAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G+ L+                 C    C N+ GSY C C  GY
Sbjct: 427 SVGFRLS-VDGRSCEDINECSSSPCSQ-ECANVYGSYQCYCRRGY 469



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
           C + G E    +C    GYQ + +     V+  D++EC      C  G +C NT GSF C
Sbjct: 190 CRDTGDEV---VCSCFVGYQLLSDG----VSCEDVNECITGSHSCRLGESCINTVGSFRC 242

Query: 157 ----TCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVC----LCPEGYV 204
               +CG G+ L                  C P  +C+N  GS+ C     C  G++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299


>Z98047-1|CAI19628.1|  703|Homo sapiens fibulin 1 protein.
          Length = 703

 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 68/221 (30%), Positives = 90/221 (40%), Gaps = 31/221 (14%)

Query: 3   GFNCTDVDECKSP-QSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKV 59
           G  C DVDEC  P + C  G +C+N+ GS+ C C   Y        C D  + + Y G++
Sbjct: 351 GTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL 410

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPGGPG- 115
                   C    E +    +  C CSVG   +  G  C+   E  S    Q C    G 
Sbjct: 411 --------CGHKCENTLGSYL--CSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGS 460

Query: 116 YQPVLEPPSYV-----VTLADIDECAAHEG--LCAHGTCTNTFGSFVCTC-GAGWSLAPX 167
           YQ        +     VT  DIDECA   G  +C++  C N  GSF C+C  +G+ LAP 
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPN 519

Query: 168 XXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGY 203
                           C     C N+ G + CL   CPE Y
Sbjct: 520 GRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 23/214 (10%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C+    C+  QC +T     C C   Y+L+SDG +C D  +    G    R G E+C 
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC-ITGSHSCRLG-ESCI 234

Query: 70  DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG---YQPVLEP 122
           ++         ++C         N C    E  S  +  L    C    G    +P L+ 
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294

Query: 123 PSYVVTLA-----DIDECAAHEGLCAHG-TCTNTFGSFVC-----TCGAGWSLAPXXXXX 171
            S  +  A     DI+EC +    C  G TC NT GS+ C      CG G+ L       
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354

Query: 172 XXXXXXXRP-DVCGPG-VCRNLPGSYVCLCPEGY 203
                   P + CG G  C N PGS+ C C  GY
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 68/227 (29%), Positives = 89/227 (39%), Gaps = 33/227 (14%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SR 51
           G +C DV+EC     SC+ G+ CINT GS+ C+    C   YEL  D  +C D     S 
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESG 269

Query: 52  KARCYGKVDLRS--GTETCRDSDELSEDGTMAAC--CCSVGAAWGNYCDPCP-------E 100
              C      ++  G+  CR   +        A   C  +     +   PCP        
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECL-SISAPCPIGHTCINT 328

Query: 101 PGSEAYRQLCPG-GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTC 158
            GS   ++  P  G GY    E    V    D+DECA     C  G  C N+ GSF C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCV----DVDECAPPAEPCGKGHRCVNSPGSFRCEC 384

Query: 159 GAGWSLAPXXXXXXXXXXXXR-PD-VCGPGVCRNLPGSYVCLCPEGY 203
             G+                R P  +CG   C N  GSY+C C  G+
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGF 430



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 64/225 (28%), Positives = 91/225 (40%), Gaps = 40/225 (17%)

Query: 5   NCTDVDECKSP-QSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SRKA 53
           +C D+DEC+S   +C     C NT GS+ CR    C   +   + G  C D     S  A
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISA 317

Query: 54  RC---------YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE 104
            C          G    +     C     L+E+GT    C  V     + C P  EP  +
Sbjct: 318 PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR---CVDV-----DECAPPAEPCGK 369

Query: 105 AYRQLCPGGPG-YQPVLEPPSYVVTLA----DIDECAAHEG-LCAHGTCTNTFGSFVCTC 158
            +R  C   PG ++   +   Y   ++    D++EC  + G LC H  C NT GS++C+C
Sbjct: 370 GHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSC 426

Query: 159 GAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G+ L+                 C    C N+ GSY C C  GY
Sbjct: 427 SVGFRLS-VDGRSCEDINECSSSPCSQ-ECANVYGSYQCYCRRGY 469



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
           C + G E    +C    GYQ + +     V+  D++EC      C  G +C NT GSF C
Sbjct: 190 CRDTGDEV---VCSCFVGYQLLSDG----VSCEDVNECITGSHSCRLGESCINTVGSFRC 242

Query: 157 ----TCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVC----LCPEGYV 204
               +CG G+ L                  C P  +C+N  GS+ C     C  G++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299


>Z95331-3|CAI41717.1|  703|Homo sapiens fibulin 1 protein.
          Length = 703

 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 68/221 (30%), Positives = 90/221 (40%), Gaps = 31/221 (14%)

Query: 3   GFNCTDVDECKSP-QSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKV 59
           G  C DVDEC  P + C  G +C+N+ GS+ C C   Y        C D  + + Y G++
Sbjct: 351 GTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL 410

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPGGPG- 115
                   C    E +    +  C CSVG   +  G  C+   E  S    Q C    G 
Sbjct: 411 --------CGHKCENTLGSYL--CSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGS 460

Query: 116 YQPVLEPPSYV-----VTLADIDECAAHEG--LCAHGTCTNTFGSFVCTC-GAGWSLAPX 167
           YQ        +     VT  DIDECA   G  +C++  C N  GSF C+C  +G+ LAP 
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPN 519

Query: 168 XXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGY 203
                           C     C N+ G + CL   CPE Y
Sbjct: 520 GRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 23/214 (10%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C+    C+  QC +T     C C   Y+L+SDG +C D  +    G    R G E+C 
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC-ITGSHSCRLG-ESCI 234

Query: 70  DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG---YQPVLEP 122
           ++         ++C         N C    E  S  +  L    C    G    +P L+ 
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294

Query: 123 PSYVVTLA-----DIDECAAHEGLCAHG-TCTNTFGSFVC-----TCGAGWSLAPXXXXX 171
            S  +  A     DI+EC +    C  G TC NT GS+ C      CG G+ L       
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354

Query: 172 XXXXXXXRP-DVCGPG-VCRNLPGSYVCLCPEGY 203
                   P + CG G  C N PGS+ C C  GY
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 68/227 (29%), Positives = 89/227 (39%), Gaps = 33/227 (14%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SR 51
           G +C DV+EC     SC+ G+ CINT GS+ C+    C   YEL  D  +C D     S 
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESG 269

Query: 52  KARCYGKVDLRS--GTETCRDSDELSEDGTMAAC--CCSVGAAWGNYCDPCP-------E 100
              C      ++  G+  CR   +        A   C  +     +   PCP        
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECL-SISAPCPIGHTCINT 328

Query: 101 PGSEAYRQLCPG-GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTC 158
            GS   ++  P  G GY    E    V    D+DECA     C  G  C N+ GSF C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCV----DVDECAPPAEPCGKGHRCVNSPGSFRCEC 384

Query: 159 GAGWSLAPXXXXXXXXXXXXR-PD-VCGPGVCRNLPGSYVCLCPEGY 203
             G+                R P  +CG   C N  GSY+C C  G+
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGF 430



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 64/225 (28%), Positives = 91/225 (40%), Gaps = 40/225 (17%)

Query: 5   NCTDVDECKSP-QSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SRKA 53
           +C D+DEC+S   +C     C NT GS+ CR    C   +   + G  C D     S  A
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISA 317

Query: 54  RC---------YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE 104
            C          G    +     C     L+E+GT    C  V     + C P  EP  +
Sbjct: 318 PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR---CVDV-----DECAPPAEPCGK 369

Query: 105 AYRQLCPGGPG-YQPVLEPPSYVVTLA----DIDECAAHEG-LCAHGTCTNTFGSFVCTC 158
            +R  C   PG ++   +   Y   ++    D++EC  + G LC H  C NT GS++C+C
Sbjct: 370 GHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSC 426

Query: 159 GAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G+ L+                 C    C N+ GSY C C  GY
Sbjct: 427 SVGFRLS-VDGRSCEDINECSSSPCSQ-ECANVYGSYQCYCRRGY 469



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
           C + G E    +C    GYQ + +     V+  D++EC      C  G +C NT GSF C
Sbjct: 190 CRDTGDEV---VCSCFVGYQLLSDG----VSCEDVNECITGSHSCRLGESCINTVGSFRC 242

Query: 157 ----TCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVC----LCPEGYV 204
               +CG G+ L                  C P  +C+N  GS+ C     C  G++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299


>AL021391-3|CAI18930.1|  703|Homo sapiens fibulin 1 protein.
          Length = 703

 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 68/221 (30%), Positives = 90/221 (40%), Gaps = 31/221 (14%)

Query: 3   GFNCTDVDECKSP-QSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKV 59
           G  C DVDEC  P + C  G +C+N+ GS+ C C   Y        C D  + + Y G++
Sbjct: 351 GTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL 410

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPGGPG- 115
                   C    E +    +  C CSVG   +  G  C+   E  S    Q C    G 
Sbjct: 411 --------CGHKCENTLGSYL--CSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGS 460

Query: 116 YQPVLEPPSYV-----VTLADIDECAAHEG--LCAHGTCTNTFGSFVCTC-GAGWSLAPX 167
           YQ        +     VT  DIDECA   G  +C++  C N  GSF C+C  +G+ LAP 
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPN 519

Query: 168 XXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGY 203
                           C     C N+ G + CL   CPE Y
Sbjct: 520 GRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 23/214 (10%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C+    C+  QC +T     C C   Y+L+SDG +C D  +    G    R G E+C 
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC-ITGSHSCRLG-ESCI 234

Query: 70  DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG---YQPVLEP 122
           ++         ++C         N C    E  S  +  L    C    G    +P L+ 
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294

Query: 123 PSYVVTLA-----DIDECAAHEGLCAHG-TCTNTFGSFVC-----TCGAGWSLAPXXXXX 171
            S  +  A     DI+EC +    C  G TC NT GS+ C      CG G+ L       
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354

Query: 172 XXXXXXXRP-DVCGPG-VCRNLPGSYVCLCPEGY 203
                   P + CG G  C N PGS+ C C  GY
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 68/227 (29%), Positives = 89/227 (39%), Gaps = 33/227 (14%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SR 51
           G +C DV+EC     SC+ G+ CINT GS+ C+    C   YEL  D  +C D     S 
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESG 269

Query: 52  KARCYGKVDLRS--GTETCRDSDELSEDGTMAAC--CCSVGAAWGNYCDPCP-------E 100
              C      ++  G+  CR   +        A   C  +     +   PCP        
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECL-SISAPCPIGHTCINT 328

Query: 101 PGSEAYRQLCPG-GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTC 158
            GS   ++  P  G GY    E    V    D+DECA     C  G  C N+ GSF C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCV----DVDECAPPAEPCGKGHRCVNSPGSFRCEC 384

Query: 159 GAGWSLAPXXXXXXXXXXXXR-PD-VCGPGVCRNLPGSYVCLCPEGY 203
             G+                R P  +CG   C N  GSY+C C  G+
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGF 430



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 64/225 (28%), Positives = 91/225 (40%), Gaps = 40/225 (17%)

Query: 5   NCTDVDECKSP-QSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SRKA 53
           +C D+DEC+S   +C     C NT GS+ CR    C   +   + G  C D     S  A
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISA 317

Query: 54  RC---------YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE 104
            C          G    +     C     L+E+GT    C  V     + C P  EP  +
Sbjct: 318 PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR---CVDV-----DECAPPAEPCGK 369

Query: 105 AYRQLCPGGPG-YQPVLEPPSYVVTLA----DIDECAAHEG-LCAHGTCTNTFGSFVCTC 158
            +R  C   PG ++   +   Y   ++    D++EC  + G LC H  C NT GS++C+C
Sbjct: 370 GHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSC 426

Query: 159 GAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G+ L+                 C    C N+ GSY C C  GY
Sbjct: 427 SVGFRLS-VDGRSCEDINECSSSPCSQ-ECANVYGSYQCYCRRGY 469



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
           C + G E    +C    GYQ + +     V+  D++EC      C  G +C NT GSF C
Sbjct: 190 CRDTGDEV---VCSCFVGYQLLSDG----VSCEDVNECITGSHSCRLGESCINTVGSFRC 242

Query: 157 ----TCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVC----LCPEGYV 204
               +CG G+ L                  C P  +C+N  GS+ C     C  G++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299


>AK075566-1|BAC11705.1|  638|Homo sapiens protein ( Homo sapiens
           cDNA PSEC0266 fis, clone NT2RP3003649, highly similar to
           Homo sapiens fibulin-1D mRNA. ).
          Length = 638

 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 68/221 (30%), Positives = 90/221 (40%), Gaps = 31/221 (14%)

Query: 3   GFNCTDVDECKSP-QSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKV 59
           G  C DVDEC  P + C  G +C+N+ GS+ C C   Y        C D  + + Y G++
Sbjct: 286 GTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL 345

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPGGPG- 115
                   C    E +    +  C CSVG   +  G  C+   E  S    Q C    G 
Sbjct: 346 --------CGHKCENTLGSYL--CSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGS 395

Query: 116 YQPVLEPPSYV-----VTLADIDECAAHEG--LCAHGTCTNTFGSFVCTC-GAGWSLAPX 167
           YQ        +     VT  DIDECA   G  +C++  C N  GSF C+C  +G+ LAP 
Sbjct: 396 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPN 454

Query: 168 XXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGY 203
                           C     C N+ G + CL   CPE Y
Sbjct: 455 GRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 495



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 23/214 (10%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C+    C+  QC +T     C C   Y+L+SDG +C D  +    G    R G E+C 
Sbjct: 113 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC-ITGSHSCRLG-ESCI 169

Query: 70  DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG---YQPVLEP 122
           ++         ++C         N C    E  S  +  L    C    G    +P L+ 
Sbjct: 170 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 229

Query: 123 PSYVVTLA-----DIDECAAHEGLCAHG-TCTNTFGSFVC-----TCGAGWSLAPXXXXX 171
            S  +  A     DI+EC +    C  G TC NT GS+ C      CG G+ L       
Sbjct: 230 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 289

Query: 172 XXXXXXXRP-DVCGPG-VCRNLPGSYVCLCPEGY 203
                   P + CG G  C N PGS+ C C  GY
Sbjct: 290 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 323



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 68/227 (29%), Positives = 89/227 (39%), Gaps = 33/227 (14%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SR 51
           G +C DV+EC     SC+ G+ CINT GS+ C+    C   YEL  D  +C D     S 
Sbjct: 146 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESG 204

Query: 52  KARCYGKVDLRS--GTETCRDSDELSEDGTMAAC--CCSVGAAWGNYCDPCP-------E 100
              C      ++  G+  CR   +        A   C  +     +   PCP        
Sbjct: 205 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECL-SISAPCPIGHTCINT 263

Query: 101 PGSEAYRQLCPG-GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTC 158
            GS   ++  P  G GY    E    V    D+DECA     C  G  C N+ GSF C C
Sbjct: 264 EGSYTCQKNVPNCGRGYHLNEEGTRCV----DVDECAPPAEPCGKGHRCVNSPGSFRCEC 319

Query: 159 GAGWSLAPXXXXXXXXXXXXR-PD-VCGPGVCRNLPGSYVCLCPEGY 203
             G+                R P  +CG   C N  GSY+C C  G+
Sbjct: 320 KTGYYFDGISRMCVDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGF 365



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 64/225 (28%), Positives = 91/225 (40%), Gaps = 40/225 (17%)

Query: 5   NCTDVDECKSP-QSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SRKA 53
           +C D+DEC+S   +C     C NT GS+ CR    C   +   + G  C D     S  A
Sbjct: 194 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISA 252

Query: 54  RC---------YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE 104
            C          G    +     C     L+E+GT    C  V     + C P  EP  +
Sbjct: 253 PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR---CVDV-----DECAPPAEPCGK 304

Query: 105 AYRQLCPGGPG-YQPVLEPPSYVVTLA----DIDECAAHEG-LCAHGTCTNTFGSFVCTC 158
            +R  C   PG ++   +   Y   ++    D++EC  + G LC H  C NT GS++C+C
Sbjct: 305 GHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSC 361

Query: 159 GAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G+ L+                 C    C N+ GSY C C  GY
Sbjct: 362 SVGFRLS-VDGRSCEDINECSSSPCSQ-ECANVYGSYQCYCRRGY 404



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
           C + G E    +C    GYQ + +     V+  D++EC      C  G +C NT GSF C
Sbjct: 125 CRDTGDEV---VCSCFVGYQLLSDG----VSCEDVNECITGSHSCRLGESCINTVGSFRC 177

Query: 157 ----TCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVC----LCPEGYV 204
               +CG G+ L                  C P  +C+N  GS+ C     C  G++
Sbjct: 178 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 234


>AF217999-1|AAG17241.1|  495|Homo sapiens unknown protein.
          Length = 495

 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 68/221 (30%), Positives = 90/221 (40%), Gaps = 31/221 (14%)

Query: 3   GFNCTDVDECKSP-QSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKV 59
           G  C DVDEC  P + C  G +C+N+ GS+ C C   Y        C D  + + Y G++
Sbjct: 221 GTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL 280

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPGGPG- 115
                   C    E +    +  C CSVG   +  G  C+   E  S    Q C    G 
Sbjct: 281 --------CGHKCENTLGSYL--CSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGS 330

Query: 116 YQPVLEPPSYV-----VTLADIDECAAHEG--LCAHGTCTNTFGSFVCTC-GAGWSLAPX 167
           YQ        +     VT  DIDECA   G  +C++  C N  GSF C+C  +G+ LAP 
Sbjct: 331 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPN 389

Query: 168 XXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGY 203
                           C     C N+ G + CL   CPE Y
Sbjct: 390 GRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 430



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 23/214 (10%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C+    C+  QC +T     C C   Y+L+SDG +C D  +    G    R G E+C 
Sbjct: 48  DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC-ITGSHSCRLG-ESCI 104

Query: 70  DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG---YQPVLEP 122
           ++         ++C         N C    E  S  +  L    C    G    +P L+ 
Sbjct: 105 NTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 164

Query: 123 PSYVVTLA-----DIDECAAHEGLCAHG-TCTNTFGSFVC-----TCGAGWSLAPXXXXX 171
            S  +  A     DI+EC +    C  G TC NT GS+ C      CG G+ L       
Sbjct: 165 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRC 224

Query: 172 XXXXXXXRP-DVCGPG-VCRNLPGSYVCLCPEGY 203
                   P + CG G  C N PGS+ C C  GY
Sbjct: 225 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 258



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 68/227 (29%), Positives = 89/227 (39%), Gaps = 33/227 (14%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SR 51
           G +C DV+EC     SC+ G+ CINT GS+ C+    C   YEL  D  +C D     S 
Sbjct: 81  GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESG 139

Query: 52  KARCYGKVDLRS--GTETCRDSDELSEDGTMAAC--CCSVGAAWGNYCDPCP-------E 100
              C      ++  G+  CR   +        A   C  +     +   PCP        
Sbjct: 140 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECL-SISAPCPIGHTCINT 198

Query: 101 PGSEAYRQLCPG-GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTC 158
            GS   ++  P  G GY    E    V    D+DECA     C  G  C N+ GSF C C
Sbjct: 199 EGSYTCQKNVPNCGRGYHLNEEGTRCV----DVDECAPPAEPCGKGHRCVNSPGSFRCEC 254

Query: 159 GAGWSLAPXXXXXXXXXXXXR-PD-VCGPGVCRNLPGSYVCLCPEGY 203
             G+                R P  +CG   C N  GSY+C C  G+
Sbjct: 255 KTGYYFDGISRMCVDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGF 300



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 64/225 (28%), Positives = 91/225 (40%), Gaps = 40/225 (17%)

Query: 5   NCTDVDECKSP-QSCQYGQ-CINTQGSYTCR----CPPNYELVSDGTACYD-----SRKA 53
           +C D+DEC+S   +C     C NT GS+ CR    C   +   + G  C D     S  A
Sbjct: 129 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISA 187

Query: 54  RC---------YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE 104
            C          G    +     C     L+E+GT    C  V     + C P  EP  +
Sbjct: 188 PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR---CVDV-----DECAPPAEPCGK 239

Query: 105 AYRQLCPGGPG-YQPVLEPPSYVVTLA----DIDECAAHEG-LCAHGTCTNTFGSFVCTC 158
            +R  C   PG ++   +   Y   ++    D++EC  + G LC H  C NT GS++C+C
Sbjct: 240 GHR--CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSC 296

Query: 159 GAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G+ L+                 C    C N+ GSY C C  GY
Sbjct: 297 SVGFRLS-VDGRSCEDINECSSSPCSQ-ECANVYGSYQCYCRRGY 339



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
           C + G E    +C    GYQ + +     V+  D++EC      C  G +C NT GSF C
Sbjct: 60  CRDTGDEV---VCSCFVGYQLLSDG----VSCEDVNECITGSHSCRLGESCINTVGSFRC 112

Query: 157 ----TCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVC----LCPEGYV 204
               +CG G+ L                  C P  +C+N  GS+ C     C  G++
Sbjct: 113 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 169


>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
           translocation-associated (Drosophila) protein.
          Length = 2555

 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 62/211 (29%), Positives = 91/211 (43%), Gaps = 34/211 (16%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRC-----PPNYELVSDGTACYDSRKARC 55
           G +C T+++EC S Q C++G  C +   +Y C C      PN E+  D  A        C
Sbjct: 597 GHHCETNINECSS-QPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTC 655

Query: 56  YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQLCPG 112
             K+D   G E C  + E    G+M  C  ++    GN C     C E G   +   CP 
Sbjct: 656 LDKID---GYE-C--ACEPGYTGSM--CNINIDECAGNPCHNGGTC-EDGINGFTCRCP- 705

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
             GY    +P      L++++EC ++   C HG C ++   + C C  GWS         
Sbjct: 706 -EGYH---DP----TCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGWS--GTNCDIN 753

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P V G G C+++   YVC C EG+
Sbjct: 754 NNECESNPCVNG-GTCKDMTSGYVCTCREGF 783



 Score = 59.7 bits (138), Expect = 8e-09
 Identities = 58/209 (27%), Positives = 76/209 (36%), Gaps = 23/209 (11%)

Query: 3   GFNCT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           G  CT DVDEC+  P +CQ G  C NT G Y C C   +          D   A C+   
Sbjct: 289 GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGA 348

Query: 60  DLRSGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
                  +          G +      C S     G+ CD  P  G    + +C    GY
Sbjct: 349 TCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNG----KAICTCPSGY 404

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                 P+      D+DEC+     C H G C NT GSF C C  G++  P         
Sbjct: 405 TG----PA---CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT-GPRCEIDVNEC 456

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                + C     C +  G + C+C  GY
Sbjct: 457 VS---NPCQNDATCLDQIGEFQCICMPGY 482



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 57/208 (27%), Positives = 79/208 (37%), Gaps = 29/208 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  D+DEC  P  C YG C +   ++TC C P Y     G  C ++    C  +   
Sbjct: 560 GTHCEVDIDEC-DPDPCHYGSCKDGVATFTCLCRPGY----TGHHC-ETNINECSSQPCR 613

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQP 118
             G  TC+D D          C C  G    N     D C     ++   L     GY+ 
Sbjct: 614 HGG--TCQDRD------NAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCL-DKIDGYEC 664

Query: 119 VLEPPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E P Y  ++   +IDECA +   C + GTC +    F C C  G+             
Sbjct: 665 ACE-PGYTGSMCNINIDECAGNP--CHNGGTCEDGINGFTCRCPEGY----HDPTCLSEV 717

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                + C  G CR+    Y C C  G+
Sbjct: 718 NECNSNPCVHGACRDSLNGYKCDCDPGW 745



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 55/204 (26%), Positives = 76/204 (37%), Gaps = 26/204 (12%)

Query: 8   DVDEC-KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           DV+EC + P  C++G  C N  GSY C C   +     G  C +     C        GT
Sbjct: 178 DVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHT----GPNC-ERPYVPCSPSPCQNGGT 232

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQ-LCPGGPGYQPVLEP 122
             CR + +++ +     C C  G   G  C+   +  PG+       C  G        P
Sbjct: 233 --CRPTGDVTHE-----CACLPGFT-GQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCP 284

Query: 123 PSYV--VTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
           P +       D+DEC      C +G TC NT G + C C  GW+                
Sbjct: 285 PEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASA-- 342

Query: 180 PDVCGPG-VCRNLPGSYVCLCPEG 202
              C  G  C +   S+ C CP G
Sbjct: 343 --ACFHGATCHDRVASFYCECPHG 364



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 61/214 (28%), Positives = 78/214 (36%), Gaps = 29/214 (13%)

Query: 3    GFNC-TDVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            G  C  D++EC  SP  C++G  C NT G Y C C   Y   +  T   D R   C+   
Sbjct: 863  GQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGG 920

Query: 60   DLRSGTETCRDSDELSEDGTMAA----CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG-P 114
                G  T          GT        C S     G  C  C     ++Y   CP G  
Sbjct: 921  SCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDC----VDSYTCTCPAGFS 976

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
            G       P       D  E +   G    GTC +   SF C C  G++           
Sbjct: 977  GIHCENNTP-------DCTESSCFNG----GTCVDGINSFTCLCPPGFT--GSYCQHDVN 1023

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                +P + G G C++  GSY C CP+GY   PN
Sbjct: 1024 ECDSQPCLHG-GTCQDGCGSYRCTCPQGYTG-PN 1055



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 57/214 (26%), Positives = 84/214 (39%), Gaps = 32/214 (14%)

Query: 3    GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G NC TD+D+C+ P  C  G  C +   +  C C P +     GT C +     C     
Sbjct: 901  GRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDIN-EC----- 949

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQ-LCPGGPG 115
                ++ CR+    ++      C C  G + G +C+     C E  S  +    C  G  
Sbjct: 950  ---ASDPCRNGANCTDCVDSYTCTCPAGFS-GIHCENNTPDCTE--SSCFNGGTCVDGIN 1003

Query: 116  YQPVLEPPSYVVTLA--DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                L PP +  +    D++EC +    C HG TC +  GS+ CTC  G++  P      
Sbjct: 1004 SFTCLCPPGFTGSYCQHDVNECDSQP--CLHGGTCQDGCGSYRCTCPQGYT-GPNCQNLV 1060

Query: 173  XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
                   P   G G C      Y C CP G+  +
Sbjct: 1061 HWCDSS-PCKNG-GKCWQTHTQYRCECPSGWTGL 1092



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 26/201 (12%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           DV+EC S        C++  G + C C P YE    G  C +     C     L +G   
Sbjct: 452 DVNECVSNPCQNDATCLDQIGEFQCICMPGYE----GVHC-EVNTDECASSPCLHNG--- 503

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQPVLEPP 123
            R  D+++E      C C  G   G+ C    D C     +   + C  GP     +   
Sbjct: 504 -RCLDKINE----FQCECPTGFT-GHLCQYDVDECASTPCKNGAK-CLDGPNTYTCVCTE 556

Query: 124 SYVVT--LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
            Y  T    DIDEC      C +G+C +   +F C C  G++               +P 
Sbjct: 557 GYTGTHCEVDIDECDPDP--CHYGSCKDGVATFTCLCRPGYT--GHHCETNINECSSQPC 612

Query: 182 VCGPGVCRNLPGSYVCLCPEG 202
             G G C++   +Y+C C +G
Sbjct: 613 RHG-GTCQDRDNAYLCFCLKG 632



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 62/222 (27%), Positives = 80/222 (36%), Gaps = 41/222 (18%)

Query: 2    PGFN---CT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYG 57
            PGF    C  DV+EC S      G C +  GSY C CP  Y     G  C  +    C  
Sbjct: 1011 PGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY----TGPNC-QNLVHWC-- 1063

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAW-GNYCD-PCPEPGSEAYRQ------- 108
                   +  C++  +  +  T   C C  G  W G YCD P       A RQ       
Sbjct: 1064 ------DSSPCKNGGKCWQTHTQYRCECPSG--WTGLYCDVPSVSCEVAAQRQGVDVARL 1115

Query: 109  -----LCPGGPGYQPVLEPPSYVVTLAD--IDECAAHEGLCAHG-TCTNTFGSFVCTCGA 160
                 LC              Y  +  +  +DEC+     C +G TCT+  G + C C A
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVA 1173

Query: 161  GWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
            G+                 P   G G C +LP +Y C CP G
Sbjct: 1174 GYH--GVNCSEEIDECLSHPCQNG-GTCLDLPNTYKCSCPRG 1212



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 57/218 (26%), Positives = 76/218 (34%), Gaps = 26/218 (11%)

Query: 3    GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC + V  C S      G+C  T   Y C CP  +     G  C D     C      
Sbjct: 1053 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT----GLYC-DVPSVSCEVAAQ- 1106

Query: 62   RSGTET---CRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEAYRQLCPGG 113
            R G +    C+      + G    C C  G   G+YC    D C P P           G
Sbjct: 1107 RQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT-GSYCEDLVDECSPSPCQNGATCTDYLG 1165

Query: 114  PGYQPVLEPPSYVVTLAD-IDECAAHEGLCAHG-TCTNTFGSFVCTC-----GAGWSLAP 166
             GY        + V  ++ IDEC +H   C +G TC +   ++ C+C     G    +  
Sbjct: 1166 -GYSCKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQGVHCEINV 1222

Query: 167  XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                         P     G C +  G Y C CP G+V
Sbjct: 1223 DDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1260



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 50/171 (29%), Positives = 66/171 (38%), Gaps = 31/171 (18%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  ++D+C S   C  G C++    Y C C P Y     G+ C +     C G    
Sbjct: 635 GPNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGYT----GSMC-NINIDECAGNPCH 688

Query: 62  RSGTETCRDSDELSEDGTMAACC-CSVGAAWGNYCDP-CPEPGSEAYRQLCPGGP----- 114
             GT  C       EDG     C C  G     Y DP C    +E     C  G      
Sbjct: 689 NGGT--C-------EDGINGFTCRCPEG-----YHDPTCLSEVNECNSNPCVHGACRDSL 734

Query: 115 -GYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWS 163
            GY+   +P  +  T  DI+        C +G TC +    +VCTC  G+S
Sbjct: 735 NGYKCDCDP-GWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFS 784



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 58/212 (27%), Positives = 77/212 (36%), Gaps = 32/212 (15%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC T+++EC S      G CI+    Y C C   Y     G  C +   A C      
Sbjct: 785 GPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY----TGATC-EVVLAPC-APSPC 838

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP------- 114
           R+G E CR     SED    +C C  G  W      C    +E     C  G        
Sbjct: 839 RNGGE-CRQ----SEDYESFSCVCPTG--WQG--QTCEVDINECVLSPCRHGASCQNTHG 889

Query: 115 GYQPVLEPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
           GY+   +   S      DID+C  +   C + G+CT+   +  C C  G+          
Sbjct: 890 GYRCHCQAGYSGRNCETDIDDCRPNP--CHNGGSCTDGINTAFCDCLPGF----RGTFCE 943

Query: 173 XXXXXXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
                   D C  G  C +   SY C CP G+
Sbjct: 944 EDINECASDPCRNGANCTDCVDSYTCTCPAGF 975



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 53/216 (24%), Positives = 78/216 (36%), Gaps = 30/216 (13%)

Query: 1   MPGF---NCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF   NC + +D+C        G C++   +Y CRCPP +     G  C +     C 
Sbjct: 246 LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEW----TGQYCTED-VDECQ 300

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGPG 115
              +      TC +    +  G    C C  G  W    + C E   +     C  G   
Sbjct: 301 LMPNACQNGGTCHN----THGG--YNCVCVNG--WTG--EDCSENIDDCASAACFHGATC 350

Query: 116 YQPVLE-----PPSYVVTLADIDECAAHEGLCAHGT-C-TNTF-GSFVCTCGAGWSLAPX 167
           +  V       P      L  +++ A     C  G+ C TN   G  +CTC +G++  P 
Sbjct: 351 HDRVASFYCECPHGRTGLLCHLND-ACISNPCNEGSNCDTNPVNGKAICTCPSGYT-GPA 408

Query: 168 XXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                             G C N  GS+ C C +GY
Sbjct: 409 CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY 444



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/212 (24%), Positives = 74/212 (34%), Gaps = 29/212 (13%)

Query: 3    GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC++ +DEC S      G C++   +Y C CP      + G  C +     C   VD 
Sbjct: 1177 GVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRG----TQGVHC-EINVDDCNPPVDP 1231

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGSEAYRQL--- 109
             S +  C ++    +     +C C  G   G  C+         PC   G++   Q    
Sbjct: 1232 VSRSPKCFNNGTCVDQVGGYSCTCPPGFV-GERCEGDVNECLSNPCDARGTQNCVQRVND 1290

Query: 110  --CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPX 167
              C    G+         V+       C  + G CA    +NT   F+C C AG+  A  
Sbjct: 1291 FHCECRAGHTG--RRCESVINGCKGKPC-KNGGTCA--VASNTARGFICKCPAGFEGATC 1345

Query: 168  XXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                              G C + P S  CLC
Sbjct: 1346 ENDARTCGSLR---CLNGGTCISGPRSPTCLC 1374



 Score = 34.7 bits (76), Expect = 0.27
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 8/73 (10%)

Query: 133 DECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV-CRN 190
           DECA+    C H G C +    F C C  G++                P  C  G  C +
Sbjct: 492 DECASSP--CLHNGRCLDKINEFQCECPTGFT--GHLCQYDVDECASTP--CKNGAKCLD 545

Query: 191 LPGSYVCLCPEGY 203
            P +Y C+C EGY
Sbjct: 546 GPNTYTCVCTEGY 558


>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
           translocation-associated (Drosophila) protein.
          Length = 2555

 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 62/211 (29%), Positives = 91/211 (43%), Gaps = 34/211 (16%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRC-----PPNYELVSDGTACYDSRKARC 55
           G +C T+++EC S Q C++G  C +   +Y C C      PN E+  D  A        C
Sbjct: 597 GHHCETNINECSS-QPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTC 655

Query: 56  YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQLCPG 112
             K+D   G E C  + E    G+M  C  ++    GN C     C E G   +   CP 
Sbjct: 656 LDKID---GYE-C--ACEPGYTGSM--CNINIDECAGNPCHNGGTC-EDGINGFTCRCP- 705

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
             GY    +P      L++++EC ++   C HG C ++   + C C  GWS         
Sbjct: 706 -EGYH---DP----TCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGWS--GTNCDIN 753

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P V G G C+++   YVC C EG+
Sbjct: 754 NNECESNPCVNG-GTCKDMTSGYVCTCREGF 783



 Score = 59.7 bits (138), Expect = 8e-09
 Identities = 58/209 (27%), Positives = 76/209 (36%), Gaps = 23/209 (11%)

Query: 3   GFNCT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           G  CT DVDEC+  P +CQ G  C NT G Y C C   +          D   A C+   
Sbjct: 289 GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGA 348

Query: 60  DLRSGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
                  +          G +      C S     G+ CD  P  G    + +C    GY
Sbjct: 349 TCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNG----KAICTCPSGY 404

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                 P+      D+DEC+     C H G C NT GSF C C  G++  P         
Sbjct: 405 TG----PA---CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT-GPRCEIDVNEC 456

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                + C     C +  G + C+C  GY
Sbjct: 457 VS---NPCQNDATCLDQIGEFQCICMPGY 482



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 57/208 (27%), Positives = 79/208 (37%), Gaps = 29/208 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  D+DEC  P  C YG C +   ++TC C P Y     G  C ++    C  +   
Sbjct: 560 GTHCEVDIDEC-DPDPCHYGSCKDGVATFTCLCRPGY----TGHHC-ETNINECSSQPCR 613

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQP 118
             G  TC+D D          C C  G    N     D C     ++   L     GY+ 
Sbjct: 614 HGG--TCQDRD------NAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCL-DKIDGYEC 664

Query: 119 VLEPPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E P Y  ++   +IDECA +   C + GTC +    F C C  G+             
Sbjct: 665 ACE-PGYTGSMCNINIDECAGNP--CHNGGTCEDGINGFTCRCPEGY----HDPTCLSEV 717

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                + C  G CR+    Y C C  G+
Sbjct: 718 NECNSNPCVHGACRDSLNGYKCDCDPGW 745



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 55/204 (26%), Positives = 76/204 (37%), Gaps = 26/204 (12%)

Query: 8   DVDEC-KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           DV+EC + P  C++G  C N  GSY C C   +     G  C +     C        GT
Sbjct: 178 DVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHT----GPNC-ERPYVPCSPSPCQNGGT 232

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQ-LCPGGPGYQPVLEP 122
             CR + +++ +     C C  G   G  C+   +  PG+       C  G        P
Sbjct: 233 --CRPTGDVTHE-----CACLPGFT-GQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCP 284

Query: 123 PSYV--VTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
           P +       D+DEC      C +G TC NT G + C C  GW+                
Sbjct: 285 PEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASA-- 342

Query: 180 PDVCGPG-VCRNLPGSYVCLCPEG 202
              C  G  C +   S+ C CP G
Sbjct: 343 --ACFHGATCHDRVASFYCECPHG 364



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 61/214 (28%), Positives = 78/214 (36%), Gaps = 29/214 (13%)

Query: 3    GFNC-TDVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            G  C  D++EC  SP  C++G  C NT G Y C C   Y   +  T   D R   C+   
Sbjct: 863  GQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGG 920

Query: 60   DLRSGTETCRDSDELSEDGTMAA----CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG-P 114
                G  T          GT        C S     G  C  C     ++Y   CP G  
Sbjct: 921  SCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDC----VDSYTCTCPAGFS 976

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
            G       P       D  E +   G    GTC +   SF C C  G++           
Sbjct: 977  GIHCENNTP-------DCTESSCFNG----GTCVDGINSFTCLCPPGFT--GSYCQHDVN 1023

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                +P + G G C++  GSY C CP+GY   PN
Sbjct: 1024 ECDSQPCLHG-GTCQDGCGSYRCTCPQGYTG-PN 1055



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 57/214 (26%), Positives = 84/214 (39%), Gaps = 32/214 (14%)

Query: 3    GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G NC TD+D+C+ P  C  G  C +   +  C C P +     GT C +     C     
Sbjct: 901  GRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDIN-EC----- 949

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQ-LCPGGPG 115
                ++ CR+    ++      C C  G + G +C+     C E  S  +    C  G  
Sbjct: 950  ---ASDPCRNGANCTDCVDSYTCTCPAGFS-GIHCENNTPDCTE--SSCFNGGTCVDGIN 1003

Query: 116  YQPVLEPPSYVVTLA--DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                L PP +  +    D++EC +    C HG TC +  GS+ CTC  G++  P      
Sbjct: 1004 SFTCLCPPGFTGSYCQHDVNECDSQP--CLHGGTCQDGCGSYRCTCPQGYT-GPNCQNLV 1060

Query: 173  XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
                   P   G G C      Y C CP G+  +
Sbjct: 1061 HWCDSS-PCKNG-GKCWQTHTQYRCECPSGWTGL 1092



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 26/201 (12%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           DV+EC S        C++  G + C C P YE    G  C +     C     L +G   
Sbjct: 452 DVNECVSNPCQNDATCLDQIGEFQCICMPGYE----GVHC-EVNTDECASSPCLHNG--- 503

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQPVLEPP 123
            R  D+++E      C C  G   G+ C    D C     +   + C  GP     +   
Sbjct: 504 -RCLDKINE----FQCECPTGFT-GHLCQYDVDECASTPCKNGAK-CLDGPNTYTCVCTE 556

Query: 124 SYVVT--LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
            Y  T    DIDEC      C +G+C +   +F C C  G++               +P 
Sbjct: 557 GYTGTHCEVDIDECDPDP--CHYGSCKDGVATFTCLCRPGYT--GHHCETNINECSSQPC 612

Query: 182 VCGPGVCRNLPGSYVCLCPEG 202
             G G C++   +Y+C C +G
Sbjct: 613 RHG-GTCQDRDNAYLCFCLKG 632



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 62/222 (27%), Positives = 80/222 (36%), Gaps = 41/222 (18%)

Query: 2    PGFN---CT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYG 57
            PGF    C  DV+EC S      G C +  GSY C CP  Y     G  C  +    C  
Sbjct: 1011 PGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY----TGPNC-QNLVHWC-- 1063

Query: 58   KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAW-GNYCD-PCPEPGSEAYRQ------- 108
                   +  C++  +  +  T   C C  G  W G YCD P       A RQ       
Sbjct: 1064 ------DSSPCKNGGKCWQTHTQYRCECPSG--WTGLYCDVPSVSCEVAAQRQGVDVARL 1115

Query: 109  -----LCPGGPGYQPVLEPPSYVVTLAD--IDECAAHEGLCAHG-TCTNTFGSFVCTCGA 160
                 LC              Y  +  +  +DEC+     C +G TCT+  G + C C A
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVA 1173

Query: 161  GWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
            G+                 P   G G C +LP +Y C CP G
Sbjct: 1174 GYH--GVNCSEEIDECLSHPCQNG-GTCLDLPNTYKCSCPRG 1212



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 57/218 (26%), Positives = 76/218 (34%), Gaps = 26/218 (11%)

Query: 3    GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC + V  C S      G+C  T   Y C CP  +     G  C D     C      
Sbjct: 1053 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT----GLYC-DVPSVSCEVAAQ- 1106

Query: 62   RSGTET---CRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEAYRQLCPGG 113
            R G +    C+      + G    C C  G   G+YC    D C P P           G
Sbjct: 1107 RQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT-GSYCEDLVDECSPSPCQNGATCTDYLG 1165

Query: 114  PGYQPVLEPPSYVVTLAD-IDECAAHEGLCAHG-TCTNTFGSFVCTC-----GAGWSLAP 166
             GY        + V  ++ IDEC +H   C +G TC +   ++ C+C     G    +  
Sbjct: 1166 -GYSCKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQGVHCEINV 1222

Query: 167  XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                         P     G C +  G Y C CP G+V
Sbjct: 1223 DDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1260



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 50/171 (29%), Positives = 66/171 (38%), Gaps = 31/171 (18%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  ++D+C S   C  G C++    Y C C P Y     G+ C +     C G    
Sbjct: 635 GPNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGYT----GSMC-NINIDECAGNPCH 688

Query: 62  RSGTETCRDSDELSEDGTMAACC-CSVGAAWGNYCDP-CPEPGSEAYRQLCPGGP----- 114
             GT  C       EDG     C C  G     Y DP C    +E     C  G      
Sbjct: 689 NGGT--C-------EDGINGFTCRCPEG-----YHDPTCLSEVNECNSNPCVHGACRDSL 734

Query: 115 -GYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWS 163
            GY+   +P  +  T  DI+        C +G TC +    +VCTC  G+S
Sbjct: 735 NGYKCDCDP-GWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFS 784



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 58/212 (27%), Positives = 77/212 (36%), Gaps = 32/212 (15%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC T+++EC S      G CI+    Y C C   Y     G  C +   A C      
Sbjct: 785 GPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY----TGATC-EVVLAPC-APSPC 838

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP------- 114
           R+G E CR     SED    +C C  G  W      C    +E     C  G        
Sbjct: 839 RNGGE-CRQ----SEDYESFSCVCPTG--WQG--QTCEVDINECVLSPCRHGASCQNTHG 889

Query: 115 GYQPVLEPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
           GY+   +   S      DID+C  +   C + G+CT+   +  C C  G+          
Sbjct: 890 GYRCHCQAGYSGRNCETDIDDCRPNP--CHNGGSCTDGINTAFCDCLPGF----RGTFCE 943

Query: 173 XXXXXXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
                   D C  G  C +   SY C CP G+
Sbjct: 944 EDINECASDPCRNGANCTDCVDSYTCTCPAGF 975



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 53/216 (24%), Positives = 78/216 (36%), Gaps = 30/216 (13%)

Query: 1   MPGF---NCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF   NC + +D+C        G C++   +Y CRCPP +     G  C +     C 
Sbjct: 246 LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEW----TGQYCTED-VDECQ 300

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGPG 115
              +      TC +    +  G    C C  G  W    + C E   +     C  G   
Sbjct: 301 LMPNACQNGGTCHN----THGG--YNCVCVNG--WTG--EDCSENIDDCASAACFHGATC 350

Query: 116 YQPVLE-----PPSYVVTLADIDECAAHEGLCAHGT-C-TNTF-GSFVCTCGAGWSLAPX 167
           +  V       P      L  +++ A     C  G+ C TN   G  +CTC +G++  P 
Sbjct: 351 HDRVASFYCECPHGRTGLLCHLND-ACISNPCNEGSNCDTNPVNGKAICTCPSGYT-GPA 408

Query: 168 XXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                             G C N  GS+ C C +GY
Sbjct: 409 CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY 444



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/212 (24%), Positives = 74/212 (34%), Gaps = 29/212 (13%)

Query: 3    GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC++ +DEC S      G C++   +Y C CP      + G  C +     C   VD 
Sbjct: 1177 GVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRG----TQGVHC-EINVDDCNPPVDP 1231

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGSEAYRQL--- 109
             S +  C ++    +     +C C  G   G  C+         PC   G++   Q    
Sbjct: 1232 VSRSPKCFNNGTCVDQVGGYSCTCPPGFV-GERCEGDVNECLSNPCDARGTQNCVQRVND 1290

Query: 110  --CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPX 167
              C    G+         V+       C  + G CA    +NT   F+C C AG+  A  
Sbjct: 1291 FHCECRAGHTG--RRCESVINGCKGKPC-KNGGTCA--VASNTARGFICKCPAGFEGATC 1345

Query: 168  XXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                              G C + P S  CLC
Sbjct: 1346 ENDARTCGSLR---CLNGGTCISGPRSPTCLC 1374



 Score = 34.7 bits (76), Expect = 0.27
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 8/73 (10%)

Query: 133 DECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV-CRN 190
           DECA+    C H G C +    F C C  G++                P  C  G  C +
Sbjct: 492 DECASSP--CLHNGRCLDKINEFQCECPTGFT--GHLCQYDVDECASTP--CKNGAKCLD 545

Query: 191 LPGSYVCLCPEGY 203
            P +Y C+C EGY
Sbjct: 546 GPNTYTCVCTEGY 558


>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein
           variant protein.
          Length = 2067

 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 62/211 (29%), Positives = 91/211 (43%), Gaps = 34/211 (16%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRC-----PPNYELVSDGTACYDSRKARC 55
           G +C T+++EC S Q C++G  C +   +Y C C      PN E+  D  A        C
Sbjct: 109 GHHCETNINECSS-QPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTC 167

Query: 56  YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQLCPG 112
             K+D   G E C  + E    G+M  C  ++    GN C     C E G   +   CP 
Sbjct: 168 LDKID---GYE-C--ACEPGYTGSM--CNINIDECAGNPCHNGGTC-EDGINGFTCRCP- 217

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
             GY    +P      L++++EC ++   C HG C ++   + C C  GWS         
Sbjct: 218 -EGYH---DP----TCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGWS--GTNCDIN 265

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P V G G C+++   YVC C EG+
Sbjct: 266 NNECESNPCVNG-GTCKDMTSGYVCTCREGF 295



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 57/208 (27%), Positives = 79/208 (37%), Gaps = 29/208 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  D+DEC  P  C YG C +   ++TC C P Y     G  C ++    C  +   
Sbjct: 72  GTHCEVDIDEC-DPDPCHYGSCKDGVATFTCLCRPGY----TGHHC-ETNINECSSQPCR 125

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQP 118
             G  TC+D D          C C  G    N     D C     ++   L     GY+ 
Sbjct: 126 HGG--TCQDRD------NAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCL-DKIDGYEC 176

Query: 119 VLEPPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E P Y  ++   +IDECA +   C + GTC +    F C C  G+             
Sbjct: 177 ACE-PGYTGSMCNINIDECAGNP--CHNGGTCEDGINGFTCRCPEGY----HDPTCLSEV 229

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                + C  G CR+    Y C C  G+
Sbjct: 230 NECNSNPCVHGACRDSLNGYKCDCDPGW 257



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 61/214 (28%), Positives = 78/214 (36%), Gaps = 29/214 (13%)

Query: 3   GFNC-TDVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           G  C  D++EC  SP  C++G  C NT G Y C C   Y   +  T   D R   C+   
Sbjct: 375 GQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGG 432

Query: 60  DLRSGTETCRDSDELSEDGTMAA----CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG-P 114
               G  T          GT        C S     G  C  C     ++Y   CP G  
Sbjct: 433 SCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDC----VDSYTCTCPAGFS 488

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
           G       P       D  E +   G    GTC +   SF C C  G++           
Sbjct: 489 GIHCENNTP-------DCTESSCFNG----GTCVDGINSFTCLCPPGFT--GSYCQHDVN 535

Query: 175 XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
               +P + G G C++  GSY C CP+GY   PN
Sbjct: 536 ECDSQPCLHG-GTCQDGCGSYRCTCPQGYTG-PN 567



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 57/214 (26%), Positives = 84/214 (39%), Gaps = 32/214 (14%)

Query: 3   GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G NC TD+D+C+ P  C  G  C +   +  C C P +     GT C +     C     
Sbjct: 413 GRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDIN-EC----- 461

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQ-LCPGGPG 115
               ++ CR+    ++      C C  G + G +C+     C E  S  +    C  G  
Sbjct: 462 ---ASDPCRNGANCTDCVDSYTCTCPAGFS-GIHCENNTPDCTE--SSCFNGGTCVDGIN 515

Query: 116 YQPVLEPPSYVVTLA--DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXX 172
               L PP +  +    D++EC +    C HG TC +  GS+ CTC  G++  P      
Sbjct: 516 SFTCLCPPGFTGSYCQHDVNECDSQP--CLHGGTCQDGCGSYRCTCPQGYT-GPNCQNLV 572

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
                  P   G G C      Y C CP G+  +
Sbjct: 573 HWCDSS-PCKNG-GKCWQTHTQYRCECPSGWTGL 604



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 62/222 (27%), Positives = 80/222 (36%), Gaps = 41/222 (18%)

Query: 2   PGFN---CT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYG 57
           PGF    C  DV+EC S      G C +  GSY C CP  Y     G  C  +    C  
Sbjct: 523 PGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY----TGPNC-QNLVHWC-- 575

Query: 58  KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAW-GNYCD-PCPEPGSEAYRQ------- 108
                  +  C++  +  +  T   C C  G  W G YCD P       A RQ       
Sbjct: 576 ------DSSPCKNGGKCWQTHTQYRCECPSG--WTGLYCDVPSVSCEVAAQRQGVDVARL 627

Query: 109 -----LCPGGPGYQPVLEPPSYVVTLAD--IDECAAHEGLCAHG-TCTNTFGSFVCTCGA 160
                LC              Y  +  +  +DEC+     C +G TCT+  G + C C A
Sbjct: 628 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVA 685

Query: 161 GWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
           G+                 P   G G C +LP +Y C CP G
Sbjct: 686 GYH--GVNCSEEIDECLSHPCQNG-GTCLDLPNTYKCSCPRG 724



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 57/218 (26%), Positives = 76/218 (34%), Gaps = 26/218 (11%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC + V  C S      G+C  T   Y C CP  +     G  C D     C      
Sbjct: 565 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT----GLYC-DVPSVSCEVAAQ- 618

Query: 62  RSGTET---CRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEAYRQLCPGG 113
           R G +    C+      + G    C C  G   G+YC    D C P P           G
Sbjct: 619 RQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT-GSYCEDLVDECSPSPCQNGATCTDYLG 677

Query: 114 PGYQPVLEPPSYVVTLAD-IDECAAHEGLCAHG-TCTNTFGSFVCTC-----GAGWSLAP 166
            GY        + V  ++ IDEC +H   C +G TC +   ++ C+C     G    +  
Sbjct: 678 -GYSCKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQGVHCEINV 734

Query: 167 XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                        P     G C +  G Y C CP G+V
Sbjct: 735 DDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 772



 Score = 46.4 bits (105), Expect = 8e-05
 Identities = 51/205 (24%), Positives = 76/205 (37%), Gaps = 33/205 (16%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC-YDSRKARCYGKVDLRSGTE 66
           + DEC S      G+C++    + C CP  +     G  C YD         VD  + T 
Sbjct: 2   NTDECASSPCLHNGRCLDKINEFQCECPTGF----TGHLCQYD---------VDECAST- 47

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEAYRQLCPGGPGYQPVLE 121
            C++  +  +      C C+ G   G +C    D C P+P    +   C  G      L 
Sbjct: 48  PCKNGAKCLDGPNTYTCVCTEGYT-GTHCEVDIDECDPDP---CHYGSCKDGVATFTCLC 103

Query: 122 PPSYV--VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            P Y       +I+EC++    C H GTC +   +++C C  G +  P            
Sbjct: 104 RPGYTGHHCETNINECSSQP--CRHGGTCQDRDNAYLCFCLKG-TTGPNCEINLDDCAS- 159

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
               C  G C +    Y C C  GY
Sbjct: 160 --SPCDSGTCLDKIDGYECACEPGY 182



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 50/171 (29%), Positives = 66/171 (38%), Gaps = 31/171 (18%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  ++D+C S   C  G C++    Y C C P Y     G+ C +     C G    
Sbjct: 147 GPNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGYT----GSMC-NINIDECAGNPCH 200

Query: 62  RSGTETCRDSDELSEDGTMAACC-CSVGAAWGNYCDP-CPEPGSEAYRQLCPGGP----- 114
             GT  C       EDG     C C  G     Y DP C    +E     C  G      
Sbjct: 201 NGGT--C-------EDGINGFTCRCPEG-----YHDPTCLSEVNECNSNPCVHGACRDSL 246

Query: 115 -GYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWS 163
            GY+   +P  +  T  DI+        C +G TC +    +VCTC  G+S
Sbjct: 247 NGYKCDCDP-GWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFS 296



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 58/212 (27%), Positives = 77/212 (36%), Gaps = 32/212 (15%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC T+++EC S      G CI+    Y C C   Y     G  C +   A C      
Sbjct: 297 GPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY----TGATC-EVVLAPC-APSPC 350

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP------- 114
           R+G E CR     SED    +C C  G  W      C    +E     C  G        
Sbjct: 351 RNGGE-CRQ----SEDYESFSCVCPTG--WQG--QTCEVDINECVLSPCRHGASCQNTHG 401

Query: 115 GYQPVLEPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
           GY+   +   S      DID+C  +   C + G+CT+   +  C C  G+          
Sbjct: 402 GYRCHCQAGYSGRNCETDIDDCRPNP--CHNGGSCTDGINTAFCDCLPGF----RGTFCE 455

Query: 173 XXXXXXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
                   D C  G  C +   SY C CP G+
Sbjct: 456 EDINECASDPCRNGANCTDCVDSYTCTCPAGF 487



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/212 (24%), Positives = 74/212 (34%), Gaps = 29/212 (13%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC++ +DEC S      G C++   +Y C CP      + G  C +     C   VD 
Sbjct: 689 GVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRG----TQGVHC-EINVDDCNPPVDP 743

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGSEAYRQL--- 109
            S +  C ++    +     +C C  G   G  C+         PC   G++   Q    
Sbjct: 744 VSRSPKCFNNGTCVDQVGGYSCTCPPGFV-GERCEGDVNECLSNPCDARGTQNCVQRVND 802

Query: 110 --CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPX 167
             C    G+         V+       C  + G CA    +NT   F+C C AG+  A  
Sbjct: 803 FHCECRAGHTG--RRCESVINGCKGKPC-KNGGTCA--VASNTARGFICKCPAGFEGATC 857

Query: 168 XXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                             G C + P S  CLC
Sbjct: 858 ENDARTCGSLR---CLNGGTCISGPRSPTCLC 886


>AL133553-4|CAI17860.1|  240|Homo sapiens protein ( Human DNA
           sequence from clone GS1-174L6 on chromosome 1. ).
          Length = 240

 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 66/208 (31%), Positives = 85/208 (40%), Gaps = 27/208 (12%)

Query: 28  GSYTCRCPPNYELVSDGTACYDSRKAR---CYGK---VDLRSG---TETCRDSDELSEDG 78
           GS+ C C P Y+L   G  C D  + R   C       + R G    + C +    +E+G
Sbjct: 3   GSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 60

Query: 79  TMAACC-CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
           T      C  G     Y   C E    +YR +CP G   Q V  P        DIDEC  
Sbjct: 61  TCIDIDECKDGTHQCRYNQIC-ENTRGSYRCVCPRGYRSQGVGRP------CMDIDEC-E 112

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV-CGPG-VCRNLPGSY 195
           +   C H  C NTFGS+ C C  G+ L                +V CGP  +C N+ GSY
Sbjct: 113 NTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSY 171

Query: 196 VCL---CPEGYVAMPNGSQYLLQNLSTN 220
            C+   CP  Y   P  S + L+N   N
Sbjct: 172 QCIDTPCPPNYQRDP-VSGFCLKNCPPN 198



 Score = 59.7 bits (138), Expect = 8e-09
 Identities = 23/47 (48%), Positives = 31/47 (65%), Gaps = 1/47 (2%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G  C D+DEC++  +CQ+ +C NT GSY C CPP Y+L  +G  C D
Sbjct: 102 GRPCMDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQD 147



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 46/169 (27%), Positives = 63/169 (37%), Gaps = 23/169 (13%)

Query: 1   MPGFNCTDVDECKSPQSCQYGQ-CINTQGSYTC--RCPPNYELVSDGTACYDSRKARCYG 57
           + G  C DV+EC+    C+  Q C NT+G Y C   CP       +GT         C  
Sbjct: 15  LKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT---------CID 64

Query: 58  KVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE----PGSEAYRQLCPGG 113
             + + GT  CR +           C C  G        PC +      ++A +  C   
Sbjct: 65  IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECENTDACQHECKNT 124

Query: 114 PGYQPVLEPPSYVV-----TLADIDECAAHEGLCA-HGTCTNTFGSFVC 156
            G    + PP Y +     T  DIDEC      C  +  C N  GS+ C
Sbjct: 125 FGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 173


>Z99756-1|CAI18854.1|  988|Homo sapiens protein ( Human DNA sequence
           from clone RP1-100N22 on chromosome  22q13.31-13.33.  ).
          Length = 988

 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 59/207 (28%), Positives = 77/207 (37%), Gaps = 21/207 (10%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVS---DGTACYDSRKARC-YGK 58
           G NC + D       C +      +G   C C P ++L     D T   +     C +  
Sbjct: 163 GMNCMNKDH-----GCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSC 217

Query: 59  VDLRSG-TETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
            D  +G T  C     L  DG      C+V       CD   +  +   R  CP G   Q
Sbjct: 218 EDTDTGPTCGCHQKYALHSDGRTCIETCAVN---NGGCDRTCKDTATGVRCSCPVGFTLQ 274

Query: 118 PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
           P  +      T  DI+EC  + G C H  C NT GSF C C  G+ L             
Sbjct: 275 PDGK------TCKDINECLVNNGGCDH-FCRNTVGSFECGCRKGYKLLTDERTCQDIDEC 327

Query: 178 XRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                C   +C N PGS+ CLC  GY+
Sbjct: 328 SFERTCDH-ICINSPGSFQCLCHRGYI 353



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 58/195 (29%), Positives = 71/195 (36%), Gaps = 26/195 (13%)

Query: 18  CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSED 77
           CQ+  C +T    TC C   Y L SDG  C ++    C   V+      TC+D+      
Sbjct: 213 CQHS-CEDTDTGPTCGCHQKYALHSDGRTCIET----C--AVNNGGCDRTCKDT------ 259

Query: 78  GTMAACCCSVGAAW---GNYCDPCPE--PGSEAYRQLCPGGPGYQPVLEPPSYVV----- 127
            T   C C VG      G  C    E    +      C    G         Y +     
Sbjct: 260 ATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDER 319

Query: 128 TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV 187
           T  DIDEC+  E  C H  C N+ GSF C C  G+ L                  C  G 
Sbjct: 320 TCQDIDECS-FERTCDH-ICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG- 376

Query: 188 CRNLPGSYVCLCPEG 202
           C N  GSY C+CP G
Sbjct: 377 CVNTKGSYECVCPPG 391



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 55/209 (26%), Positives = 75/209 (35%), Gaps = 16/209 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY--DSRKARCYGKVD 60
           G NC DVDEC+         C+N  GSY C+C   + L  +   C    +    C  K  
Sbjct: 112 GHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKD- 170

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPG---GP 114
                  CR   E  + G   AC C  G   A     C      G+   +  C     GP
Sbjct: 171 -HGCAHICR---ETPKGG--VACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGP 224

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
                 +   +      I+ CA + G C   TC +T     C+C  G++L P        
Sbjct: 225 TCGCHQKYALHSDGRTCIETCAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTCKDI 283

Query: 175 XXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                 +      CRN  GS+ C C +GY
Sbjct: 284 NECLVNNGGCDHFCRNTVGSFECGCRKGY 312



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 26/60 (43%), Positives = 33/60 (55%), Gaps = 2/60 (3%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           +C DVDEC  S  SC  G C+NT+GSY C CPP   L  +G  C ++ K     K   R+
Sbjct: 359 HCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRA 417



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 34/119 (28%), Positives = 44/119 (36%), Gaps = 7/119 (5%)

Query: 96  DPCPEPGSEAYRQ-LCPGGPGYQPVLEPPSYV---VTLADIDECAA--HEGLCAHGTCTN 149
           D C E   + +   +C   P     L  P Y        DIDEC    + G C H  C N
Sbjct: 35  DECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVH-ECIN 93

Query: 150 TFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
             G++ CTC  G+ LA               +     +C N  GSY C C  G+    N
Sbjct: 94  IPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDN 152



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 4/50 (8%)

Query: 3   GFNCTDVDECKSPQ---SCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G  C D+DEC++      C + +CIN  G+Y C C   + L  DG  C D
Sbjct: 69  GKQCEDIDECENDYYNGGCVH-ECINIPGNYRCTCFDGFMLAHDGHNCLD 117



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 2/44 (4%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           C D+DEC   ++C +  CIN+ GS+ C C   Y L    T C D
Sbjct: 321 CQDIDECSFERTCDH-ICINSPGSFQCLCHRGYILYGT-THCGD 362



 Score = 34.3 bits (75), Expect = 0.36
 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 6/51 (11%)

Query: 1  MPGFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYD 49
          +PG    DVDEC +    C     C NT  SY C C P Y+   +G  C D
Sbjct: 28 LPG--SVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCED 74


>Z97832-1|CAI20187.1|  993|Homo sapiens protein ( Human DNA sequence
           from clone RP3-329A5 on chromosome 6p21.1-21.33. ).
          Length = 993

 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 55/187 (29%), Positives = 70/187 (37%), Gaps = 24/187 (12%)

Query: 27  QGSYTCRCPPNYELVSDGTACYDSRKARC-YGKVDLRSGTETCRDSDELSEDG------- 78
           +G   C C P +EL  +   C    K  C YG    +    TC D+++    G       
Sbjct: 177 KGGIACECRPGFELTKNQRDC----KLTCNYGNGGCQ---HTCDDTEQGPRCGCHIKFVL 229

Query: 79  -TMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
            T    C    A     CD      +      CP G   QP  +      T  DIDEC  
Sbjct: 230 HTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRK------TCKDIDECRL 283

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVC 197
           + G C H  C NT GSF C+C  G+ L                  C   +C N PGS+ C
Sbjct: 284 NNGGCDH-ICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDH-ICVNTPGSFQC 341

Query: 198 LCPEGYV 204
           LC  GY+
Sbjct: 342 LCHRGYL 348



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 54/213 (25%), Positives = 74/213 (34%), Gaps = 14/213 (6%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC DVDEC          C+N  GSY C C   + L  +   C   R       ++  
Sbjct: 107 GHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCI-QRPEEGMNCMNKN 165

Query: 63  SG-TETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP---EPGSEAYRQLCPG---GPG 115
            G    CR   E  + G   AC C  G         C      G+   +  C     GP 
Sbjct: 166 HGCAHICR---ETPKGG--IACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPR 220

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               ++   +      I+ CA + G C    C +      CTC  G+ L P         
Sbjct: 221 CGCHIKFVLHTDGKTCIETCAVNNGGC-DSKCHDAATGVHCTCPVGFMLQPDRKTCKDID 279

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                +     +CRN  GS+ C C +GY  + N
Sbjct: 280 ECRLNNGGCDHICRNTVGSFECSCKKGYKLLIN 312



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 60/213 (28%), Positives = 79/213 (37%), Gaps = 24/213 (11%)

Query: 2   PGFNCT-DVDECKSPQSCQYGQ------CINTQGSYTCRCPPNYELVSDGTACYDS---R 51
           PGF  T +  +CK   +C YG       C +T+    C C   + L +DG  C ++    
Sbjct: 186 PGFELTKNQRDCKL--TCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVN 243

Query: 52  KARCYGKV-DLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
              C  K  D  +G   TC     L  D              G  CD        ++   
Sbjct: 244 NGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGG-CDHICRNTVGSFECS 302

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX 169
           C    GY+ ++   +      DIDEC+  +  C H  C NT GSF C C  G+ L     
Sbjct: 303 CK--KGYKLLINERN----CQDIDECS-FDRTCDH-ICVNTPGSFQCLCHRGYLLYGITH 354

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                        C  G C N PGSY C CP G
Sbjct: 355 CGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 26/69 (37%), Positives = 33/69 (47%), Gaps = 5/69 (7%)

Query: 5   NCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNY-ELVSDGTACYDSRKARCYGKVDLR 62
           +C DVDEC   +  C++G CINT GSY C CP     L  +G  C +  K  C G     
Sbjct: 354 HCGDVDECSINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTEPLK--CQGSPGAS 410

Query: 63  SGTETCRDS 71
               +C  S
Sbjct: 411 KAMLSCNRS 419



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 3/49 (6%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C DVDEC+   +  C +  C+N  G+Y C C   + L  DG  C D
Sbjct: 65  GKHCKDVDECEREDNAGCVH-DCVNIPGNYRCTCYDGFHLAHDGHNCLD 112



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 131 DIDECAAHEGL-CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           D+DEC   +   C H  C N  G++ CTC  G+ LA               +      C 
Sbjct: 70  DVDECEREDNAGCVHD-CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCV 128

Query: 190 NLPGSYVCLCPEGYVAMPN 208
           N+ GSY C C EG+    N
Sbjct: 129 NMMGSYECHCREGFFLSDN 147



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 4/91 (4%)

Query: 125 YVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC 183
           Y     D+DEC      C     C NT  S+ C C +G++               R D  
Sbjct: 23  YSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNA 80

Query: 184 G-PGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
           G    C N+PG+Y C C +G+    +G   L
Sbjct: 81  GCVHDCVNIPGNYRCTCYDGFHLAHDGHNCL 111



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 18/44 (40%), Positives = 20/44 (45%), Gaps = 4/44 (9%)

Query: 8  DVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYD 49
          DVDEC +   +C     C NT  SY C C   Y    DG  C D
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKD 70


>Z82214-3|CAI21674.1|  988|Homo sapiens protein ( Human DNA sequence
           from clone RP3-526I14 on chromosome 22. ).
          Length = 988

 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 59/207 (28%), Positives = 77/207 (37%), Gaps = 21/207 (10%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVS---DGTACYDSRKARC-YGK 58
           G NC + D       C +      +G   C C P ++L     D T   +     C +  
Sbjct: 163 GMNCMNKDH-----GCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSC 217

Query: 59  VDLRSG-TETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
            D  +G T  C     L  DG      C+V       CD   +  +   R  CP G   Q
Sbjct: 218 EDTDTGPTCGCHQKYALHSDGRTCIETCAVN---NGGCDRTCKDTATGVRCSCPVGFTLQ 274

Query: 118 PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
           P  +      T  DI+EC  + G C H  C NT GSF C C  G+ L             
Sbjct: 275 PDGK------TCKDINECLVNNGGCDH-FCRNTVGSFECGCRKGYKLLTDERTCQDIDEC 327

Query: 178 XRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                C   +C N PGS+ CLC  GY+
Sbjct: 328 SFERTCDH-ICINSPGSFQCLCHRGYI 353



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 58/195 (29%), Positives = 71/195 (36%), Gaps = 26/195 (13%)

Query: 18  CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSED 77
           CQ+  C +T    TC C   Y L SDG  C ++    C   V+      TC+D+      
Sbjct: 213 CQHS-CEDTDTGPTCGCHQKYALHSDGRTCIET----C--AVNNGGCDRTCKDT------ 259

Query: 78  GTMAACCCSVGAAW---GNYCDPCPE--PGSEAYRQLCPGGPGYQPVLEPPSYVV----- 127
            T   C C VG      G  C    E    +      C    G         Y +     
Sbjct: 260 ATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDER 319

Query: 128 TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV 187
           T  DIDEC+  E  C H  C N+ GSF C C  G+ L                  C  G 
Sbjct: 320 TCQDIDECS-FERTCDH-ICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG- 376

Query: 188 CRNLPGSYVCLCPEG 202
           C N  GSY C+CP G
Sbjct: 377 CVNTKGSYECVCPPG 391



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 55/209 (26%), Positives = 75/209 (35%), Gaps = 16/209 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY--DSRKARCYGKVD 60
           G NC DVDEC+         C+N  GSY C+C   + L  +   C    +    C  K  
Sbjct: 112 GHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKD- 170

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPG---GP 114
                  CR   E  + G   AC C  G   A     C      G+   +  C     GP
Sbjct: 171 -HGCAHICR---ETPKGG--VACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGP 224

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
                 +   +      I+ CA + G C   TC +T     C+C  G++L P        
Sbjct: 225 TCGCHQKYALHSDGRTCIETCAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTCKDI 283

Query: 175 XXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                 +      CRN  GS+ C C +GY
Sbjct: 284 NECLVNNGGCDHFCRNTVGSFECGCRKGY 312



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 26/60 (43%), Positives = 33/60 (55%), Gaps = 2/60 (3%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           +C DVDEC  S  SC  G C+NT+GSY C CPP   L  +G  C ++ K     K   R+
Sbjct: 359 HCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRA 417



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 34/119 (28%), Positives = 44/119 (36%), Gaps = 7/119 (5%)

Query: 96  DPCPEPGSEAYRQ-LCPGGPGYQPVLEPPSYV---VTLADIDECAA--HEGLCAHGTCTN 149
           D C E   + +   +C   P     L  P Y        DIDEC    + G C H  C N
Sbjct: 35  DECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVH-ECIN 93

Query: 150 TFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
             G++ CTC  G+ LA               +     +C N  GSY C C  G+    N
Sbjct: 94  IPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDN 152



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 4/50 (8%)

Query: 3   GFNCTDVDECKSPQ---SCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G  C D+DEC++      C + +CIN  G+Y C C   + L  DG  C D
Sbjct: 69  GKQCEDIDECENDYYNGGCVH-ECINIPGNYRCTCFDGFMLAHDGHNCLD 117



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 2/44 (4%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           C D+DEC   ++C +  CIN+ GS+ C C   Y L    T C D
Sbjct: 321 CQDIDECSFERTCDH-ICINSPGSFQCLCHRGYILYGT-THCGD 362



 Score = 34.3 bits (75), Expect = 0.36
 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 6/51 (11%)

Query: 1  MPGFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYD 49
          +PG    DVDEC +    C     C NT  SY C C P Y+   +G  C D
Sbjct: 28 LPG--SVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCED 74


>AY639608-1|AAU08347.1|  993|Homo sapiens signal peptide, CUB and
           EGF-like domain containing protein 3 protein.
          Length = 993

 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 55/187 (29%), Positives = 70/187 (37%), Gaps = 24/187 (12%)

Query: 27  QGSYTCRCPPNYELVSDGTACYDSRKARC-YGKVDLRSGTETCRDSDELSEDG------- 78
           +G   C C P +EL  +   C    K  C YG    +    TC D+++    G       
Sbjct: 177 KGGIACECRPGFELTKNQRDC----KLTCNYGNGGCQ---HTCDDTEQGPRCGCHIKFVL 229

Query: 79  -TMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
            T    C    A     CD      +      CP G   QP  +      T  DIDEC  
Sbjct: 230 HTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRK------TCKDIDECRL 283

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVC 197
           + G C H  C NT GSF C+C  G+ L                  C   +C N PGS+ C
Sbjct: 284 NNGGCDH-ICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDH-ICVNTPGSFQC 341

Query: 198 LCPEGYV 204
           LC  GY+
Sbjct: 342 LCHRGYL 348



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 54/213 (25%), Positives = 74/213 (34%), Gaps = 14/213 (6%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC DVDEC          C+N  GSY C C   + L  +   C   R       ++  
Sbjct: 107 GHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCI-QRPEEGMNCMNKN 165

Query: 63  SG-TETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP---EPGSEAYRQLCPG---GPG 115
            G    CR   E  + G   AC C  G         C      G+   +  C     GP 
Sbjct: 166 HGCAHICR---ETPKGG--IACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPR 220

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               ++   +      I+ CA + G C    C +      CTC  G+ L P         
Sbjct: 221 CGCHIKFVLHTDGKTCIETCAVNNGGC-DSKCHDAATGVHCTCPVGFMLQPDRKTCKDID 279

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                +     +CRN  GS+ C C +GY  + N
Sbjct: 280 ECRLNNGGCDHICRNTVGSFECSCKKGYKLLIN 312



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 60/213 (28%), Positives = 79/213 (37%), Gaps = 24/213 (11%)

Query: 2   PGFNCT-DVDECKSPQSCQYGQ------CINTQGSYTCRCPPNYELVSDGTACYDS---R 51
           PGF  T +  +CK   +C YG       C +T+    C C   + L +DG  C ++    
Sbjct: 186 PGFELTKNQRDCKL--TCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVN 243

Query: 52  KARCYGKV-DLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
              C  K  D  +G   TC     L  D              G  CD        ++   
Sbjct: 244 NGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGG-CDHICRNTVGSFECS 302

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX 169
           C    GY+ ++   +      DIDEC+  +  C H  C NT GSF C C  G+ L     
Sbjct: 303 CK--KGYKLLINERN----CQDIDECS-FDRTCDH-ICVNTPGSFQCLCHRGYLLYGITH 354

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                        C  G C N PGSY C CP G
Sbjct: 355 CGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 26/69 (37%), Positives = 33/69 (47%), Gaps = 5/69 (7%)

Query: 5   NCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNY-ELVSDGTACYDSRKARCYGKVDLR 62
           +C DVDEC   +  C++G CINT GSY C CP     L  +G  C +  K  C G     
Sbjct: 354 HCGDVDECSINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTEPLK--CQGSPGAS 410

Query: 63  SGTETCRDS 71
               +C  S
Sbjct: 411 KAMLSCNRS 419



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 3/49 (6%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C DVDEC+   +  C +  C+N  G+Y C C   + L  DG  C D
Sbjct: 65  GKHCKDVDECEREDNAGCVH-DCVNIPGNYRCTCYDGFHLAHDGHNCLD 112



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 131 DIDECAAHEGL-CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           D+DEC   +   C H  C N  G++ CTC  G+ LA               +      C 
Sbjct: 70  DVDECEREDNAGCVHD-CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCV 128

Query: 190 NLPGSYVCLCPEGYVAMPN 208
           N+ GSY C C EG+    N
Sbjct: 129 NMMGSYECHCREGFFLSDN 147



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 4/91 (4%)

Query: 125 YVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC 183
           Y     D+DEC      C     C NT  S+ C C +G++               R D  
Sbjct: 23  YSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNA 80

Query: 184 G-PGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
           G    C N+PG+Y C C +G+    +G   L
Sbjct: 81  GCVHDCVNIPGNYRCTCYDGFHLAHDGHNCL 111



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 18/44 (40%), Positives = 20/44 (45%), Gaps = 4/44 (9%)

Query: 8  DVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYD 49
          DVDEC +   +C     C NT  SY C C   Y    DG  C D
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKD 70


>AF452494-1|AAN76808.1|  993|Homo sapiens CUB and EGF containing
           protein protein.
          Length = 993

 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 55/187 (29%), Positives = 70/187 (37%), Gaps = 24/187 (12%)

Query: 27  QGSYTCRCPPNYELVSDGTACYDSRKARC-YGKVDLRSGTETCRDSDELSEDG------- 78
           +G   C C P +EL  +   C    K  C YG    +    TC D+++    G       
Sbjct: 177 KGGIACECRPGFELTKNQRDC----KLTCNYGNGGCQ---HTCDDTEQGPRCGCHIKFVL 229

Query: 79  -TMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
            T    C    A     CD      +      CP G   QP  +      T  DIDEC  
Sbjct: 230 HTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRK------TCKDIDECRL 283

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVC 197
           + G C H  C NT GSF C+C  G+ L                  C   +C N PGS+ C
Sbjct: 284 NNGGCDH-ICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDH-ICVNTPGSFQC 341

Query: 198 LCPEGYV 204
           LC  GY+
Sbjct: 342 LCHRGYL 348



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 54/213 (25%), Positives = 74/213 (34%), Gaps = 14/213 (6%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC DVDEC          C+N  GSY C C   + L  +   C   R       ++  
Sbjct: 107 GHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCI-QRPEEGMNCMNKN 165

Query: 63  SG-TETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP---EPGSEAYRQLCPG---GPG 115
            G    CR   E  + G   AC C  G         C      G+   +  C     GP 
Sbjct: 166 HGCAHICR---ETPKGG--IACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPR 220

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               ++   +      I+ CA + G C    C +      CTC  G+ L P         
Sbjct: 221 CGCHIKFVLHTDGKTCIETCAVNNGGC-DSKCHDAATGVHCTCPVGFMLQPDRKTCKDID 279

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                +     +CRN  GS+ C C +GY  + N
Sbjct: 280 ECRLNNGGCDHICRNTVGSFECSCKKGYKLLIN 312



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 60/213 (28%), Positives = 79/213 (37%), Gaps = 24/213 (11%)

Query: 2   PGFNCT-DVDECKSPQSCQYGQ------CINTQGSYTCRCPPNYELVSDGTACYDS---R 51
           PGF  T +  +CK   +C YG       C +T+    C C   + L +DG  C ++    
Sbjct: 186 PGFELTKNQRDCKL--TCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVN 243

Query: 52  KARCYGKV-DLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
              C  K  D  +G   TC     L  D              G  CD        ++   
Sbjct: 244 NGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGG-CDHICRNTVGSFECS 302

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX 169
           C    GY+ ++   +      DIDEC+  +  C H  C NT GSF C C  G+ L     
Sbjct: 303 CK--KGYKLLINERN----CQDIDECS-FDRTCDH-ICVNTPGSFQCLCHRGYLLYGITH 354

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                        C  G C N PGSY C CP G
Sbjct: 355 CGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 26/69 (37%), Positives = 33/69 (47%), Gaps = 5/69 (7%)

Query: 5   NCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNY-ELVSDGTACYDSRKARCYGKVDLR 62
           +C DVDEC   +  C++G CINT GSY C CP     L  +G  C +  K  C G     
Sbjct: 354 HCGDVDECSINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTEPLK--CQGSPGAS 410

Query: 63  SGTETCRDS 71
               +C  S
Sbjct: 411 KAMLSCNRS 419



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 3/49 (6%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C DVDEC+   +  C +  C+N  G+Y C C   + L  DG  C D
Sbjct: 65  GKHCKDVDECEREDNAGCVH-DCVNIPGNYRCTCYDGFHLAHDGHNCLD 112



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 131 DIDECAAHEGL-CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           D+DEC   +   C H  C N  G++ CTC  G+ LA               +      C 
Sbjct: 70  DVDECEREDNAGCVHD-CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCV 128

Query: 190 NLPGSYVCLCPEGYVAMPN 208
           N+ GSY C C EG+    N
Sbjct: 129 NMMGSYECHCREGFFLSDN 147



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 4/91 (4%)

Query: 125 YVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC 183
           Y     D+DEC      C     C NT  S+ C C +G++               R D  
Sbjct: 23  YSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNA 80

Query: 184 G-PGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
           G    C N+PG+Y C C +G+    +G   L
Sbjct: 81  GCVHDCVNIPGNYRCTCYDGFHLAHDGHNCL 111



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 18/44 (40%), Positives = 20/44 (45%), Gaps = 4/44 (9%)

Query: 8  DVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYD 49
          DVDEC +   +C     C NT  SY C C   Y    DG  C D
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKD 70


>X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein.
          Length = 1184

 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 70/211 (33%), Positives = 89/211 (42%), Gaps = 40/211 (18%)

Query: 2   PGFNCTDVDECKS-PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           P  NC D++EC S  + C+ G  CINT GSYTC+  P          C     AR Y   
Sbjct: 804 PEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP--------LIC-----ARGYHAS 850

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           D   G + C D +E  E G      C  G    N       PGS  YR  C  G      
Sbjct: 851 D--DGAK-CVDVNEC-ETGVHR---CGEGQVCHNL------PGS--YRCDCKAG------ 889

Query: 120 LEPPSYVVTLADIDECAAHEG-LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            +  ++     D++EC A  G LC H TC NT GS+ C+C +G+ LA             
Sbjct: 890 FQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLA-ADGKRCEDVNEC 947

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
               C    C N+ GSY C C +GY    +G
Sbjct: 948 EAQRCSQ-ECANIYGSYQCYCRQGYQLAEDG 977



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 62/217 (28%), Positives = 85/217 (39%), Gaps = 23/217 (10%)

Query: 3    GFNCTDVDECKSP-QSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G  C DV+EC++    C  GQ C N  GSY C C   ++  + G  C D  +  C+    
Sbjct: 853  GAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE--CWASPG 910

Query: 61   LRSGTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
             R    TC ++      G+    C S  + AA G  C+   E  ++   Q C    G   
Sbjct: 911  -RLCQHTCENTL-----GSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQ 964

Query: 119  VLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTC-GAGWSL-APXXXXX 171
                  Y +     T  DIDECA   G+     C N  GS+ C C   G+++ A      
Sbjct: 965  CYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCK 1024

Query: 172  XXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGYV 204
                       C     C N+ GS+ CL   CP  YV
Sbjct: 1025 DVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYV 1061



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 64/219 (29%), Positives = 88/219 (40%), Gaps = 31/219 (14%)

Query: 8   DVDECK--SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D DEC     + CQ+  CINT GSY C C P + L  DG  C      R  G        
Sbjct: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTC------RPEGHPPQPEAP 656

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQ-LCPGGPGYQPVLE 121
           +      E S+   +A+    +     N C    PC +  S      +C   PGY  + +
Sbjct: 657 QEPALKSEFSQ---VASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMAD 713

Query: 122 PPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVC----TCGAGWSLAPXXXXXXXXXX 176
                V+  DI+EC      C+ G  C NT GSF C    TC  G++L            
Sbjct: 714 G----VSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECA 769

Query: 177 XXRPDVCGPG-VCRNLPGSYVC----LCPEGYVAMPNGS 210
                 C PG +C+N  GS+ C     C +G++  P G+
Sbjct: 770 MG-THTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN 807



 Score = 46.4 bits (105), Expect = 8e-05
 Identities = 57/232 (24%), Positives = 88/232 (37%), Gaps = 28/232 (12%)

Query: 3   GFNCTDVDECKSP-QSCQYGQ-CINTQGSYTC----RCPPNYELVSDGTACYDSRKAR-- 54
           G +C D++EC +   +C  G+ C+NT GS+ C     C P Y L  DG  C D  +    
Sbjct: 714 GVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL-KDGE-CEDVDECAMG 771

Query: 55  ---CYGKVDLRS--GTETCRDSDELSEDGTMA---ACCCSVGAAWGNYCDPCPEPGSEAY 106
              C      ++  G+  C+ + +   DG +      C  +     +  +PC  PG    
Sbjct: 772 THTCQPGFLCQNTKGSFYCQ-ARQRCMDGFLQDPEGNCVDINECT-SLSEPC-RPGFSCI 828

Query: 107 RQLCPGGPGYQPVLEPPSYVVT-----LADIDECAAHEGLCAHG-TCTNTFGSFVCTCGA 160
             +        P++    Y  +       D++EC      C  G  C N  GS+ C C A
Sbjct: 829 NTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKA 888

Query: 161 GWSL-APXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
           G+   A              P       C N  GSY C C  G++   +G +
Sbjct: 889 GFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKR 940


>BC052263-1|AAH52263.2|  992|Homo sapiens signal peptide, CUB
           domain, EGF-like 3 protein.
          Length = 992

 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 55/187 (29%), Positives = 70/187 (37%), Gaps = 24/187 (12%)

Query: 27  QGSYTCRCPPNYELVSDGTACYDSRKARC-YGKVDLRSGTETCRDSDELSEDG------- 78
           +G   C C P +EL  +   C    K  C YG    +    TC D+++    G       
Sbjct: 176 KGGIACECRPGFELTKNQRDC----KLTCNYGNGGCQ---HTCDDTEQGPRCGCHIKFVL 228

Query: 79  -TMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
            T    C    A     CD      +      CP G   QP  +      T  DIDEC  
Sbjct: 229 HTDGKTCIETCAVNNGGCDSKCHDAAIGVHCTCPVGFMLQPDRK------TCKDIDECRL 282

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVC 197
           + G C H  C NT GSF C+C  G+ L                  C   +C N PGS+ C
Sbjct: 283 NNGGCDH-ICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDH-ICVNTPGSFQC 340

Query: 198 LCPEGYV 204
           LC  GY+
Sbjct: 341 LCHRGYL 347



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 15/213 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA-RCYGKVDL 61
           G NC DVDEC          C+N  GSY C C   + L  +   C    +   C  K   
Sbjct: 107 GHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEGMNCMNK--N 164

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCP---EPGSEAYRQLCPG---GPG 115
                 CR   E  + G   AC C  G         C      G+   +  C     GP 
Sbjct: 165 HGCAHICR---ETPKGG--IACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPR 219

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               ++   +      I+ CA + G C    C +      CTC  G+ L P         
Sbjct: 220 CGCHIKFVLHTDGKTCIETCAVNNGGC-DSKCHDAAIGVHCTCPVGFMLQPDRKTCKDID 278

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                +     +CRN  GS+ C C +GY  + N
Sbjct: 279 ECRLNNGGCDHICRNTVGSFECSCKKGYKLLIN 311



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 60/213 (28%), Positives = 78/213 (36%), Gaps = 24/213 (11%)

Query: 2   PGFNCT-DVDECKSPQSCQYGQ------CINTQGSYTCRCPPNYELVSDGTACYDS---R 51
           PGF  T +  +CK   +C YG       C +T+    C C   + L +DG  C ++    
Sbjct: 185 PGFELTKNQRDCKL--TCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVN 242

Query: 52  KARCYGKV-DLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
              C  K  D   G   TC     L  D              G  CD        ++   
Sbjct: 243 NGGCDSKCHDAAIGVHCTCPVGFMLQPDRKTCKDIDECRLNNGG-CDHICRNTVGSFECS 301

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXX 169
           C    GY+ ++   +      DIDEC+  +  C H  C NT GSF C C  G+ L     
Sbjct: 302 CK--KGYKLLINERN----CQDIDECS-FDRTCDH-ICVNTPGSFQCLCHRGYLLYGITH 353

Query: 170 XXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                        C  G C N PGSY C CP G
Sbjct: 354 CGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 385



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 26/69 (37%), Positives = 33/69 (47%), Gaps = 5/69 (7%)

Query: 5   NCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNY-ELVSDGTACYDSRKARCYGKVDLR 62
           +C DVDEC   +  C++G CINT GSY C CP     L  +G  C +  K  C G     
Sbjct: 353 HCGDVDECSINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTEPLK--CQGSPGAS 409

Query: 63  SGTETCRDS 71
               +C  S
Sbjct: 410 KAMLSCNRS 418



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 3/49 (6%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C DVDEC+   +  C +  C+N  G+Y C C   + L  DG  C D
Sbjct: 65  GKHCKDVDECEREDNAGCVH-DCVNIPGNYRCTCYDGFHLAHDGHNCLD 112



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 131 DIDECAAHEGL-CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           D+DEC   +   C H  C N  G++ CTC  G+ LA               +      C 
Sbjct: 70  DVDECEREDNAGCVHD-CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCV 128

Query: 190 NLPGSYVCLCPEGYVAMPN 208
           N+ GSY C C EG+    N
Sbjct: 129 NMMGSYECHCREGFFLSDN 147



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 4/91 (4%)

Query: 125 YVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC 183
           Y     D+DEC      C     C NT  S+ C C +G++               R D  
Sbjct: 23  YSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNA 80

Query: 184 G-PGVCRNLPGSYVCLCPEGYVAMPNGSQYL 213
           G    C N+PG+Y C C +G+    +G   L
Sbjct: 81  GCVHDCVNIPGNYRCTCYDGFHLAHDGHNCL 111



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 18/44 (40%), Positives = 20/44 (45%), Gaps = 4/44 (9%)

Query: 8  DVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYD 49
          DVDEC +   +C     C NT  SY C C   Y    DG  C D
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKD 70


>BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein.
          Length = 1184

 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 70/211 (33%), Positives = 89/211 (42%), Gaps = 40/211 (18%)

Query: 2   PGFNCTDVDECKS-PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           P  NC D++EC S  + C+ G  CINT GSYTC+  P          C     AR Y   
Sbjct: 804 PEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP--------LIC-----ARGYHAS 850

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           D   G + C D +E  E G      C  G    N       PGS  YR  C  G      
Sbjct: 851 D--DGAK-CVDVNEC-ETGVHR---CGEGQVCHNL------PGS--YRCDCKAG------ 889

Query: 120 LEPPSYVVTLADIDECAAHEG-LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            +  ++     D++EC A  G LC H TC NT GS+ C+C +G+ LA             
Sbjct: 890 FQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLA-ADGKRCEDVNEC 947

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
               C    C N+ GSY C C +GY    +G
Sbjct: 948 EAQRCSQ-ECANIYGSYQCYCRQGYQLAEDG 977



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 62/217 (28%), Positives = 85/217 (39%), Gaps = 23/217 (10%)

Query: 3    GFNCTDVDECKSP-QSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G  C DV+EC++    C  GQ C N  GSY C C   ++  + G  C D  +  C+    
Sbjct: 853  GAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE--CWASPG 910

Query: 61   LRSGTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
             R    TC ++      G+    C S  + AA G  C+   E  ++   Q C    G   
Sbjct: 911  -RLCQHTCENTL-----GSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQ 964

Query: 119  VLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTC-GAGWSL-APXXXXX 171
                  Y +     T  DIDECA   G+     C N  GS+ C C   G+++ A      
Sbjct: 965  CYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCK 1024

Query: 172  XXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGYV 204
                       C     C N+ GS+ CL   CP  YV
Sbjct: 1025 DVDECALGTHNCSEAETCHNIQGSFRCLRLECPPNYV 1061



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 64/219 (29%), Positives = 88/219 (40%), Gaps = 31/219 (14%)

Query: 8   DVDECK--SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D DEC     + CQ+  CINT GSY C C P + L  DG  C      R  G        
Sbjct: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTC------RPEGHPPQPEAP 656

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQ-LCPGGPGYQPVLE 121
           +      E S+   +A+    +     N C    PC +  S      +C   PGY  + +
Sbjct: 657 QEPALKSEFSQ---VASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMAD 713

Query: 122 PPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVC----TCGAGWSLAPXXXXXXXXXX 176
                V+  DI+EC      C+ G  C NT GSF C    TC  G++L            
Sbjct: 714 G----VSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECA 769

Query: 177 XXRPDVCGPG-VCRNLPGSYVC----LCPEGYVAMPNGS 210
                 C PG +C+N  GS+ C     C +G++  P G+
Sbjct: 770 MG-THTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN 807



 Score = 46.4 bits (105), Expect = 8e-05
 Identities = 57/232 (24%), Positives = 88/232 (37%), Gaps = 28/232 (12%)

Query: 3   GFNCTDVDECKSP-QSCQYGQ-CINTQGSYTC----RCPPNYELVSDGTACYDSRKAR-- 54
           G +C D++EC +   +C  G+ C+NT GS+ C     C P Y L  DG  C D  +    
Sbjct: 714 GVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL-KDGE-CEDVDECAMG 771

Query: 55  ---CYGKVDLRS--GTETCRDSDELSEDGTMA---ACCCSVGAAWGNYCDPCPEPGSEAY 106
              C      ++  G+  C+ + +   DG +      C  +     +  +PC  PG    
Sbjct: 772 THTCQPGFLCQNTKGSFYCQ-ARQRCMDGFLQDPEGNCVDINECT-SLSEPC-RPGFSCI 828

Query: 107 RQLCPGGPGYQPVLEPPSYVVT-----LADIDECAAHEGLCAHG-TCTNTFGSFVCTCGA 160
             +        P++    Y  +       D++EC      C  G  C N  GS+ C C A
Sbjct: 829 NTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKA 888

Query: 161 GWSL-APXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
           G+   A              P       C N  GSY C C  G++   +G +
Sbjct: 889 GFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKR 940


>AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein.
          Length = 1231

 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 70/211 (33%), Positives = 89/211 (42%), Gaps = 40/211 (18%)

Query: 2    PGFNCTDVDECKS-PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            P  NC D++EC S  + C+ G  CINT GSYTC+  P          C     AR Y   
Sbjct: 851  PEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP--------LIC-----ARGYHAS 897

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
            D   G + C D +E  E G      C  G    N       PGS  YR  C  G      
Sbjct: 898  D--DGAK-CVDVNEC-ETGVHR---CGEGQVCHNL------PGS--YRCDCKAG------ 936

Query: 120  LEPPSYVVTLADIDECAAHEG-LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
             +  ++     D++EC A  G LC H TC NT GS+ C+C +G+ LA             
Sbjct: 937  FQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLA-ADGKRCEDVNEC 994

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                C    C N+ GSY C C +GY    +G
Sbjct: 995  EAQRCSQ-ECANIYGSYQCYCRQGYQLAEDG 1024



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 62/217 (28%), Positives = 85/217 (39%), Gaps = 23/217 (10%)

Query: 3    GFNCTDVDECKSP-QSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G  C DV+EC++    C  GQ C N  GSY C C   ++  + G  C D  +  C+    
Sbjct: 900  GAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE--CWASPG 957

Query: 61   LRSGTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
             R    TC ++      G+    C S  + AA G  C+   E  ++   Q C    G   
Sbjct: 958  -RLCQHTCENTL-----GSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQ 1011

Query: 119  VLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTC-GAGWSL-APXXXXX 171
                  Y +     T  DIDECA   G+     C N  GS+ C C   G+++ A      
Sbjct: 1012 CYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCK 1071

Query: 172  XXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGYV 204
                       C     C N+ GS+ CL   CP  YV
Sbjct: 1072 DVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYV 1108



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 68/235 (28%), Positives = 85/235 (36%), Gaps = 45/235 (19%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G +C D DEC      C   Q C+NT GS+   C  +  L +DG      RK  C GK +
Sbjct: 714 GVSCEDQDECLMGAHDCSRRQFCVNTLGSF--YCVNHTVLCADGYILNAHRK--CVGKNE 769

Query: 61  LRSGTETCRDSDE----LSEDGTMAACCCSVG-------------AAWGNY-CDP---CP 99
             +   TC   +     L       A  C  G              A G + C P   C 
Sbjct: 770 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQ 829

Query: 100 EPGSEAY---RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFV 155
                 Y   RQ C  G      L+ P       DI+EC +    C  G +C NT GS+ 
Sbjct: 830 NTKGSFYCQARQRCMDG-----FLQDPE--GNCVDINECTSLSEPCRPGFSCINTVGSYT 882

Query: 156 C-----TCGAGWSLAPXXXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
           C      C  G+  +                  CG G VC NLPGSY C C  G+
Sbjct: 883 CQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF 937



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 63/219 (28%), Positives = 81/219 (36%), Gaps = 32/219 (14%)

Query: 8   DVDECK--SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D DEC     + CQ+  CINT GSY C C P + L  DG  C      R  G        
Sbjct: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTC------RPEGH---PPQP 653

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSE-AYRQLCPGGPGYQPVLE 121
           E  ++    SE   +A+    +     N C    PC +  S      +C   PGY  + +
Sbjct: 654 EAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMAD 713

Query: 122 PPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCT-----CGAGWSLAPXXXXXXXXX 175
                V+  D DEC      C+    C NT GSF C      C  G+ L           
Sbjct: 714 G----VSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVGKNE 769

Query: 176 XXXRPDVCGPGV-CRNLPGSYVC----LCPEGYVAMPNG 209
                  C  G  C N  GS+ C     C  GY A+ +G
Sbjct: 770 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDG 807



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 55/229 (24%), Positives = 84/229 (36%), Gaps = 28/229 (12%)

Query: 6   CTDVDECKSP-QSCQYGQ-CINTQGSYTC----RCPPNYELVSDGTACYDSRKAR----- 54
           C   +EC +   +C  G+ C+NT GS+ C     C P Y L  DG  C D  +       
Sbjct: 764 CVGKNECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL-KDGE-CEDVDECAMGTHT 821

Query: 55  CYGKVDLRS--GTETCRDSDELSEDGTMA---ACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
           C      ++  G+  C+ + +   DG +      C  +     +  +PC  PG      +
Sbjct: 822 CQPGFLCQNTKGSFYCQ-ARQRCMDGFLQDPEGNCVDINECT-SLSEPC-RPGFSCINTV 878

Query: 110 CPGGPGYQPVLEPPSYVVT-----LADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWS 163
                   P++    Y  +       D++EC      C  G  C N  GS+ C C AG+ 
Sbjct: 879 GSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQ 938

Query: 164 L-APXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
             A              P       C N  GSY C C  G++   +G +
Sbjct: 939 RDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKR 987


>AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein.
          Length = 1231

 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 70/211 (33%), Positives = 89/211 (42%), Gaps = 40/211 (18%)

Query: 2    PGFNCTDVDECKS-PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            P  NC D++EC S  + C+ G  CINT GSYTC+  P          C     AR Y   
Sbjct: 851  PEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP--------LIC-----ARGYHAS 897

Query: 60   DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
            D   G + C D +E  E G      C  G    N       PGS  YR  C  G      
Sbjct: 898  D--DGXK-CVDVNEC-ETGVHR---CGEGQVCHNL------PGS--YRCDCKAG------ 936

Query: 120  LEPPSYVVTLADIDECAAHEG-LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
             +  ++     D++EC A  G LC H TC NT GS+ C+C +G+ LA             
Sbjct: 937  FQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLA-ADGKRCEDVNEC 994

Query: 179  RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                C    C N+ GSY C C +GY    +G
Sbjct: 995  EAQRCSQ-ECANIYGSYQCYCRQGYQLAEDG 1024



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 62/217 (28%), Positives = 85/217 (39%), Gaps = 23/217 (10%)

Query: 3    GFNCTDVDECKSP-QSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G  C DV+EC++    C  GQ C N  GSY C C   ++  + G  C D  +  C+    
Sbjct: 900  GXKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE--CWASPG 957

Query: 61   LRSGTETCRDSDELSEDGTMAACCCS--VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
             R    TC ++      G+    C S  + AA G  C+   E  ++   Q C    G   
Sbjct: 958  -RLCQHTCENTL-----GSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQ 1011

Query: 119  VLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTC-GAGWSL-APXXXXX 171
                  Y +     T  DIDECA   G+     C N  GS+ C C   G+++ A      
Sbjct: 1012 CYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCK 1071

Query: 172  XXXXXXXRPDVCGPG-VCRNLPGSYVCL---CPEGYV 204
                       C     C N+ GS+ CL   CP  YV
Sbjct: 1072 DVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYV 1108



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 63/219 (28%), Positives = 81/219 (36%), Gaps = 32/219 (14%)

Query: 8   DVDECK--SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D DEC     + CQ+  CINT GSY C C P + L  DG  C      R  G        
Sbjct: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTC------RPEGH---PPQP 653

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYC---DPCPEPGSE-AYRQLCPGGPGYQPVLE 121
           E  ++    SE   +A+    +     N C    PC +  S      +C   PGY  + +
Sbjct: 654 EAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMAD 713

Query: 122 PPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCT-----CGAGWSLAPXXXXXXXXX 175
                V+  D DEC      C+    C NT GSF C      C  G+ L           
Sbjct: 714 G----VSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINE 769

Query: 176 XXXRPDVCGPGV-CRNLPGSYVC----LCPEGYVAMPNG 209
                  C  G  C N  GS+ C     C  GY A+ +G
Sbjct: 770 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDG 807



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 66/236 (27%), Positives = 85/236 (36%), Gaps = 47/236 (19%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTC-----------------RCPPNYELVSD 43
           G +C D DEC      C   Q C+NT GS+ C                 +C    E V+D
Sbjct: 714 GVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTD 773

Query: 44  GTACYDSRKARCYGKVDLRSGTE--TCRDSDELSEDGTMAACCCSVGAAWGNYCDP---C 98
              C  SR   C   +      +  TC     L +        C++G    + C P   C
Sbjct: 774 LHTC--SRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGT---HTCQPGFLC 828

Query: 99  PEPGSEAY---RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSF 154
                  Y   RQ C  G      L+ P       DI+EC +    C  G +C NT GS+
Sbjct: 829 QNTKGSFYCQARQRCMDG-----FLQDPE--GNCVDINECTSLSEPCRPGFSCINTVGSY 881

Query: 155 VC-----TCGAGWSLAPXXXX-XXXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEGY 203
            C      C  G+  +                  CG G VC NLPGSY C C  G+
Sbjct: 882 TCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF 937



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 56/229 (24%), Positives = 86/229 (37%), Gaps = 28/229 (12%)

Query: 6   CTDVDECKSP-QSCQYGQ-CINTQGSYTC----RCPPNYELVSDGTACYDSRKAR----- 54
           C D++EC +   +C  G+ C+NT GS+ C     C P Y L  DG  C D  +       
Sbjct: 764 CVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL-KDGE-CEDVDECAMGTHT 821

Query: 55  CYGKVDLRS--GTETCRDSDELSEDGTMA---ACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
           C      ++  G+  C+ + +   DG +      C  +     +  +PC  PG      +
Sbjct: 822 CQPGFLCQNTKGSFYCQ-ARQRCMDGFLQDPEGNCVDINECT-SLSEPC-RPGFSCINTV 878

Query: 110 CPGGPGYQPVLEPPSYVVT-----LADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWS 163
                   P++    Y  +       D++EC      C  G  C N  GS+ C C AG+ 
Sbjct: 879 GSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQ 938

Query: 164 L-APXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
             A              P       C N  GSY C C  G++   +G +
Sbjct: 939 RDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKR 987


>AF054501-1|AAC39881.1|  161|Homo sapiens latent transforming growth
           factor-beta binding protein 4 protein.
          Length = 161

 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 58/184 (31%), Positives = 70/184 (38%), Gaps = 39/184 (21%)

Query: 18  CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSED 77
           CQ G C NT GS+ C CPP +    D                       +C D DE  E 
Sbjct: 2   CQSGICTNTDGSFECICPPGHRAGPD---------------------LASCLDVDECRER 40

Query: 78  GTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
           G   A C S        C+    PGS  YR +    PGY    E      T  D+DEC  
Sbjct: 41  GP--ALCGS------QRCEN--SPGS--YRCVRDCDPGYHAGPEG-----TCDDVDECRN 83

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCRNLPGSYV 196
                AH  C N  GSF C C  G+  A                 VCG  +C N+ GS++
Sbjct: 84  RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFL 143

Query: 197 CLCP 200
           C+CP
Sbjct: 144 CVCP 147



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 30/74 (40%), Positives = 33/74 (44%), Gaps = 4/74 (5%)

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR--PDVCGPGVCRNLPGSYVCL 198
           LC  G CTNT GSF C C  G    P               P +CG   C N PGSY C+
Sbjct: 1   LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 60

Query: 199 --CPEGYVAMPNGS 210
             C  GY A P G+
Sbjct: 61  RDCDPGYHAGPEGT 74



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 10/110 (9%)

Query: 109 LCPGGPGYQPVLEPPSY-----VVTLADIDECAAH-EGLCAHGTCTNTFGSFVCT--CGA 160
           +C    G    + PP +     + +  D+DEC      LC    C N+ GS+ C   C  
Sbjct: 6   ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDP 65

Query: 161 GWSLAPXXXXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGYVAMPNG 209
           G+   P            R   CG   VC+NLPGS+ CLC +GY    +G
Sbjct: 66  GYHAGPEGTCDDVDECRNR-SFCGAHAVCQNLPGSFQCLCDQGYEGARDG 114



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 20/49 (40%), Positives = 24/49 (48%), Gaps = 1/49 (2%)

Query: 2   PGFNCTDVDECKSPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           P   C DVDEC++   C  +  C N  GS+ C C   YE   DG  C D
Sbjct: 71  PEGTCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 119



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 5/54 (9%)

Query: 5  NCTDVDECKS--PQSCQYGQCINTQGSYTC--RCPPNYELVSDGTACYDSRKAR 54
          +C DVDEC+   P  C   +C N+ GSY C   C P Y    +GT C D  + R
Sbjct: 30 SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECR 82



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 1/38 (2%)

Query: 3   GFNCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNYE 39
           G +C DV+EC++ Q  C    C N +GS+ C CP + E
Sbjct: 114 GRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 151


>AK092062-1|BAC03798.1|  880|Homo sapiens protein ( Homo sapiens
           cDNA FLJ34743 fis, clone MESAN2009019, moderately
           similar to CEGP1 protein. ).
          Length = 880

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 63/210 (30%), Positives = 83/210 (39%), Gaps = 38/210 (18%)

Query: 2   PGFNCT-DVDECKSPQSCQYGQ------CINTQGSYTCRCPPNYELVSDGTACYDSRKAR 54
           PGF  T +  +CK   +C YG       C +T+    C C   + L +DG  C   R+  
Sbjct: 57  PGFELTKNQRDCKL--TCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIGERRLE 114

Query: 55  CYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
            +      S  ETC     ++  G  + C     AA G +C              CP G 
Sbjct: 115 QHIPTQAVSN-ETCA----VNNGGCDSKCH---DAATGVHCT-------------CPVGF 153

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
             QP  +      T  DIDEC  + G C H  C NT GSF C+C  G+ L          
Sbjct: 154 MLQPDRK------TCKDIDECRLNNGGCDH-ICRNTVGSFECSCKKGYKLLINERNCQDI 206

Query: 175 XXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                   C   +C N PGS+ CLC  GY+
Sbjct: 207 DECSFDRTCDH-ICVNTPGSFQCLCHRGYL 235



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 26/69 (37%), Positives = 33/69 (47%), Gaps = 5/69 (7%)

Query: 5   NCTDVDECKSPQS-CQYGQCINTQGSYTCRCPPNY-ELVSDGTACYDSRKARCYGKVDLR 62
           +C DVDEC   +  C++G CINT GSY C CP     L  +G  C +  K  C G     
Sbjct: 241 HCGDVDECSINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTEPLK--CQGSPGAS 297

Query: 63  SGTETCRDS 71
               +C  S
Sbjct: 298 KAMLSCNRS 306



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 2/45 (4%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           NC D+DEC   ++C +  C+NT GS+ C C   Y L+   T C D
Sbjct: 202 NCQDIDECSFDRTCDH-ICVNTPGSFQCLCHRGY-LLYGITHCGD 244



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 21/76 (27%), Positives = 30/76 (39%), Gaps = 1/76 (1%)

Query: 133 DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLP 192
           + CA + G C    C +      CTC  G+ L P              +     +CRN  
Sbjct: 125 ETCAVNNGGC-DSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTV 183

Query: 193 GSYVCLCPEGYVAMPN 208
           GS+ C C +GY  + N
Sbjct: 184 GSFECSCKKGYKLLIN 199


>U03877-1|AAA65590.1|  387|Homo sapiens extracellular protein
           protein.
          Length = 387

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 56/216 (25%), Positives = 80/216 (37%), Gaps = 27/216 (12%)

Query: 6   CTDVDECKS-PQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR----CYGKV 59
           C D+DEC +   +C+  Q CIN +GS+ C+CPP Y+    G  C D  +      C+ + 
Sbjct: 65  CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQCVDIDECTIPPYCHQRC 122

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG 115
               G+  C+ S           C         N CD   +   + Y  L    C    G
Sbjct: 123 VNTPGSFYCQCSPGFQLAANNYTCVDI------NECDASNQCAQQCYNILGSFICQCNQG 176

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           Y    E  S  +   DIDEC     LC +  C N  G F C C  G+ +           
Sbjct: 177 Y----ELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQVVRSRTCQDINE 231

Query: 176 XXXRPDVCGPGVCRNLPGSYVCL----CPEGYVAMP 207
                +     +C N  G + C     C + Y+  P
Sbjct: 232 CETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTP 267



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA--------R 54
           G  C D+DEC  P  C + +C+NT GS+ C+C P ++L ++   C D  +         +
Sbjct: 103 GEQCVDIDECTIPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ 161

Query: 55  CYGKVDLRSGTETCRDSDELSEDGTMAACC--CSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
           CY    L S    C    ELS D         C   +    Y     EPG   +  +CP 
Sbjct: 162 CYN--ILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGK--FSCMCP- 215

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVC 156
             GYQ V        T  DI+EC           C N  G F C
Sbjct: 216 -QGYQVVRSR-----TCQDINECETTNECREDEMCWNYHGGFRC 253



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 36/117 (30%), Positives = 43/117 (36%), Gaps = 11/117 (9%)

Query: 93  NYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTF 151
           N  DP   P + ++R  C  G       E   + V   DIDEC A    C A   C N  
Sbjct: 36  NPADPQRIPSNPSHRIQCAAG------YEQSEHNVC-QDIDECTAGTHNCRADQVCINLR 88

Query: 152 GSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
           GSF C C  G+                 P  C    C N PGS+ C C  G+    N
Sbjct: 89  GSFACQCPPGYQKRGEQCVDIDECTI--PPYCHQR-CVNTPGSFYCQCSPGFQLAAN 142


>CR541934-1|CAG46732.1|  443|Homo sapiens EFEMP2 protein.
          Length = 443

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 27/214 (12%)

Query: 5   NCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR---CYGKV 59
           +C DVDEC ++   C+  Q C N  GSY C CP  Y  +  G  C D  + R   C  + 
Sbjct: 120 SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI--GPECVDIDECRYRYCQHRC 177

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQ-LCPGGPG 115
               G+  C+  +   + G     C  V     N CD   PC +    +Y   LC    G
Sbjct: 178 VNLPGSFRCQ-CEPGFQLGPNNRSCVDV-----NECDMGAPCEQRCFNSYGTFLCRCHQG 231

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           Y+  L    +  + +DIDEC+    LC +  C N  G F C C  G+ L           
Sbjct: 232 YE--LHRDGF--SCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGYQLLATRLCQDIDE 286

Query: 176 XXXRPDVCGPG-VCRNLPGSYVCL----CPEGYV 204
                  C     C N  G Y C+    C E Y+
Sbjct: 287 CESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYI 320



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 51/164 (31%), Positives = 71/164 (43%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCYGK 58
           G  C D+DEC+  + CQ+ +C+N  GS+ C+C P ++L  +  +C D  +    A C  +
Sbjct: 159 GPECVDIDECRY-RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQR 216

Query: 59  VDLRSGTETCR--DSDELSEDGTMAACC--CSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
                GT  CR     EL  DG   +    CS  +    Y C    EPG    R  C   
Sbjct: 217 CFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRC--VNEPG----RFSCHCP 270

Query: 114 PGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
            GYQ +           DIDEC +    C+   TC N  G + C
Sbjct: 271 QGYQLLA-----TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 49/179 (27%), Positives = 68/179 (37%), Gaps = 23/179 (12%)

Query: 34  CPPNYELVSDGTACYDSRKAR-----CYGKVDLRS--GTETCRDSDELSEDGTMAACCCS 86
           CPP YE   D  +C D  +       C    D  +  G+  C   D   + G     C  
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE---CVD 164

Query: 87  VGAAWGNYCDP-CPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH 144
           +      YC   C   PGS  +R  C   PG+Q  L P +   +  D++EC    G    
Sbjct: 165 IDECRYRYCQHRCVNLPGS--FRCQCE--PGFQ--LGPNNR--SCVDVNECDM--GAPCE 214

Query: 145 GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             C N++G+F+C C  G+ L                       C N PG + C CP+GY
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273


>BC098561-1|AAH98561.1|  493|Homo sapiens EGF-containing
           fibulin-like extracellular matrix protein 1 protein.
          Length = 493

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 56/216 (25%), Positives = 80/216 (37%), Gaps = 27/216 (12%)

Query: 6   CTDVDECKS-PQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR----CYGKV 59
           C D+DEC +   +C+  Q CIN +GS+ C+CPP Y+    G  C D  +      C+ + 
Sbjct: 171 CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQCVDIDECTIPPYCHQRC 228

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG 115
               G+  C+ S           C         N CD   +   + Y  L    C    G
Sbjct: 229 VNTPGSFYCQCSPGFQLAANNYTCVDI------NECDASNQCAQQCYNILGSFICQCNQG 282

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           Y    E  S  +   DIDEC     LC +  C N  G F C C  G+ +           
Sbjct: 283 Y----ELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQVVRSRTCQDINE 337

Query: 176 XXXRPDVCGPGVCRNLPGSYVCL----CPEGYVAMP 207
                +     +C N  G + C     C + Y+  P
Sbjct: 338 CETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTP 373



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA--------R 54
           G  C D+DEC  P  C + +C+NT GS+ C+C P ++L ++   C D  +         +
Sbjct: 209 GEQCVDIDECTIPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ 267

Query: 55  CYGKVDLRSGTETCRDSDELSEDGTMAACC--CSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
           CY    L S    C    ELS D         C   +    Y     EPG   +  +CP 
Sbjct: 268 CYN--ILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGK--FSCMCP- 321

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVC 156
             GYQ V        T  DI+EC           C N  G F C
Sbjct: 322 -QGYQVVRSR-----TCQDINECETTNECREDEMCWNYHGGFRC 359



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 57/217 (26%), Positives = 78/217 (35%), Gaps = 24/217 (11%)

Query: 6   CTDVDECKS-PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-CYGKVDLR 62
           C D+DEC   P +C+ G +C+N  G Y C       +V++     +++ A    G     
Sbjct: 42  CKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGV 101

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWG----------NYCDPCPEPGSEAYRQLCPG 112
               +   S  L   G +A+     G              N  DP   P + ++R  C  
Sbjct: 102 VAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAA 161

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXX 171
           G       E   + V   DIDEC A    C A   C N  GSF C C  G+         
Sbjct: 162 G------YEQSEHNVC-QDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVD 214

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                   P  C    C N PGS+ C C  G+    N
Sbjct: 215 IDECTI--PPYCHQR-CVNTPGSFYCQCSPGFQLAAN 248


>BC053933-1|AAH53933.1|  239|Homo sapiens EMR2 protein protein.
          Length = 239

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 56/192 (29%), Positives = 83/192 (43%), Gaps = 25/192 (13%)

Query: 26  TQGSYTCR--CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAAC 83
           TQ S  C   CP +   V+  TAC  +     + ++ + +  ETC   D+++E  T++  
Sbjct: 23  TQDSRGCARWCPQDSSCVN-ATACRCNPGFSSFSEI-ITTPMETC---DDINECATLSKV 77

Query: 84  CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV----TLADIDECAAHE 139
            C      G + D     GS  Y  +C   PGY+PV    ++      T  D+DEC  + 
Sbjct: 78  SC------GKFSDCWNTEGS--YDCVC--SPGYEPVSGAKTFKNESENTCQDVDECQQNP 127

Query: 140 GLC-AHGTCTNTFGSFVCTCGAGWSLAPX--XXXXXXXXXXXRPDVCGPGV-CRNLPGSY 195
            LC ++GTC NT GS+ C C  G+   P                + C     C N  GSY
Sbjct: 128 RLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSY 187

Query: 196 VCLCPEGYVAMP 207
            C C  G+  +P
Sbjct: 188 QCRCRPGWQPIP 199



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 51/169 (30%), Positives = 68/169 (40%), Gaps = 34/169 (20%)

Query: 2   PGFNCTDVDECK--SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           P   C D++EC   S  SC ++  C NT+GSY C C P YE VS               K
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSG-------------AK 107

Query: 59  VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                   TC+D DE  ++  +   C S G             GS      C   PG++ 
Sbjct: 108 TFKNESENTCQDVDECQQNPRL---CKSYGTCVNTL-------GS----YTCQCLPGFKF 153

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAP 166
           + E P       D++EC + +  C   T C N  GS+ C C  GW   P
Sbjct: 154 IPEDPK---VCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIP 199


>BC034949-1|AAH34949.1|  239|Homo sapiens EMR2 protein protein.
          Length = 239

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 56/192 (29%), Positives = 83/192 (43%), Gaps = 25/192 (13%)

Query: 26  TQGSYTCR--CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAAC 83
           TQ S  C   CP +   V+  TAC  +     + ++ + +  ETC   D+++E  T++  
Sbjct: 23  TQDSRGCARWCPQDSSCVN-ATACRCNPGFSSFSEI-ITTPMETC---DDINECATLSKV 77

Query: 84  CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV----TLADIDECAAHE 139
            C      G + D     GS  Y  +C   PGY+PV    ++      T  D+DEC  + 
Sbjct: 78  SC------GKFSDCWNTEGS--YDCVC--SPGYEPVSGAKTFKNESENTCQDVDECQQNP 127

Query: 140 GLC-AHGTCTNTFGSFVCTCGAGWSLAPX--XXXXXXXXXXXRPDVCGPGV-CRNLPGSY 195
            LC ++GTC NT GS+ C C  G+   P                + C     C N  GSY
Sbjct: 128 RLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSY 187

Query: 196 VCLCPEGYVAMP 207
            C C  G+  +P
Sbjct: 188 QCRCRPGWQPIP 199



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 51/169 (30%), Positives = 68/169 (40%), Gaps = 34/169 (20%)

Query: 2   PGFNCTDVDECK--SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           P   C D++EC   S  SC ++  C NT+GSY C C P YE VS               K
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSG-------------AK 107

Query: 59  VDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
                   TC+D DE  ++  +   C S G             GS      C   PG++ 
Sbjct: 108 TFKNESENTCQDVDECQQNPRL---CKSYGTCVNTL-------GS----YTCQCLPGFKF 153

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAP 166
           + E P       D++EC + +  C   T C N  GS+ C C  GW   P
Sbjct: 154 IPEDPK---VCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIP 199


>BC014410-1|AAH14410.1|  493|Homo sapiens EGF-containing
           fibulin-like extracellular matrix protein 1 protein.
          Length = 493

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 56/216 (25%), Positives = 80/216 (37%), Gaps = 27/216 (12%)

Query: 6   CTDVDECKS-PQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR----CYGKV 59
           C D+DEC +   +C+  Q CIN +GS+ C+CPP Y+    G  C D  +      C+ + 
Sbjct: 171 CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQCVDIDECTIPPYCHQRC 228

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG 115
               G+  C+ S           C         N CD   +   + Y  L    C    G
Sbjct: 229 VNTPGSFYCQCSPGFQLAANNYTCVDI------NECDASNQCAQQCYNILGSFICQCNQG 282

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           Y    E  S  +   DIDEC     LC +  C N  G F C C  G+ +           
Sbjct: 283 Y----ELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQVVRSRTCQDINE 337

Query: 176 XXXRPDVCGPGVCRNLPGSYVCL----CPEGYVAMP 207
                +     +C N  G + C     C + Y+  P
Sbjct: 338 CETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTP 373



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA--------R 54
           G  C D+DEC  P  C + +C+NT GS+ C+C P ++L ++   C D  +         +
Sbjct: 209 GEQCVDIDECTIPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ 267

Query: 55  CYGKVDLRSGTETCRDSDELSEDGTMAACC--CSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
           CY    L S    C    ELS D         C   +    Y     EPG   +  +CP 
Sbjct: 268 CYN--ILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGK--FSCMCP- 321

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVC 156
             GYQ V        T  DI+EC           C N  G F C
Sbjct: 322 -QGYQVVRSR-----TCQDINECETTNECREDEMCWNYHGGFRC 359



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 57/217 (26%), Positives = 78/217 (35%), Gaps = 24/217 (11%)

Query: 6   CTDVDECKS-PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-CYGKVDLR 62
           C D+DEC   P +C+ G +C+N  G Y C       +V++     +++ A    G     
Sbjct: 42  CKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGV 101

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWG----------NYCDPCPEPGSEAYRQLCPG 112
               +   S  L   G +A+     G              N  DP   P + ++R  C  
Sbjct: 102 VAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAA 161

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXX 171
           G       E   + V   DIDEC A    C A   C N  GSF C C  G+         
Sbjct: 162 G------YEQSEHNVC-QDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVD 214

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                   P  C    C N PGS+ C C  G+    N
Sbjct: 215 IDECTI--PPYCHQR-CVNTPGSFYCQCSPGFQLAAN 248


>BC010456-1|AAH10456.1|  443|Homo sapiens EGF-containing
           fibulin-like extracellular matrix protein 2 protein.
          Length = 443

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 27/214 (12%)

Query: 5   NCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR---CYGKV 59
           +C DVDEC ++   C+  Q C N  GSY C CP  Y  +  G  C D  + R   C  + 
Sbjct: 120 SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI--GPECVDIDECRYRYCQHRC 177

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQ-LCPGGPG 115
               G+  C+  +   + G     C  V     N CD   PC +    +Y   LC    G
Sbjct: 178 VNLPGSFRCQ-CEPGFQLGPNNRSCVDV-----NECDMGAPCEQRCFNSYGTFLCRCHQG 231

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           Y+  L    +  + +DIDEC+    LC +  C N  G F C C  G+ L           
Sbjct: 232 YE--LHRDGF--SCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGYQLLATRLCQDIDE 286

Query: 176 XXXRPDVCGPG-VCRNLPGSYVCL----CPEGYV 204
                  C     C N  G Y C+    C E Y+
Sbjct: 287 CESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYI 320



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 51/164 (31%), Positives = 71/164 (43%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCYGK 58
           G  C D+DEC+  + CQ+ +C+N  GS+ C+C P ++L  +  +C D  +    A C  +
Sbjct: 159 GPECVDIDECRY-RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQR 216

Query: 59  VDLRSGTETCR--DSDELSEDGTMAACC--CSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
                GT  CR     EL  DG   +    CS  +    Y C    EPG    R  C   
Sbjct: 217 CFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRC--VNEPG----RFSCHCP 270

Query: 114 PGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
            GYQ +           DIDEC +    C+   TC N  G + C
Sbjct: 271 QGYQLLA-----TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 49/179 (27%), Positives = 68/179 (37%), Gaps = 23/179 (12%)

Query: 34  CPPNYELVSDGTACYDSRKAR-----CYGKVDLRS--GTETCRDSDELSEDGTMAACCCS 86
           CPP YE   D  +C D  +       C    D  +  G+  C   D   + G     C  
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE---CVD 164

Query: 87  VGAAWGNYCDP-CPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH 144
           +      YC   C   PGS  +R  C   PG+Q  L P +   +  D++EC    G    
Sbjct: 165 IDECRYRYCQHRCVNLPGS--FRCQCE--PGFQ--LGPNNR--SCVDVNECDM--GAPCE 214

Query: 145 GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             C N++G+F+C C  G+ L                       C N PG + C CP+GY
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273


>AY358899-1|AAQ89258.1|  443|Homo sapiens EFEMP2 protein.
          Length = 443

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 27/214 (12%)

Query: 5   NCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR---CYGKV 59
           +C DVDEC ++   C+  Q C N  GSY C CP  Y  +  G  C D  + R   C  + 
Sbjct: 120 SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI--GPECVDIDECRYRYCQHRC 177

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQ-LCPGGPG 115
               G+  C+  +   + G     C  V     N CD   PC +    +Y   LC    G
Sbjct: 178 VNLPGSFRCQ-CEPGFQLGPNNRSCVDV-----NECDMGAPCEQRCFNSYGTFLCRCHQG 231

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           Y+  L    +  + +DIDEC+    LC +  C N  G F C C  G+ L           
Sbjct: 232 YE--LHRDGF--SCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGYQLLATRLCQDIDE 286

Query: 176 XXXRPDVCGPG-VCRNLPGSYVCL----CPEGYV 204
                  C     C N  G Y C+    C E Y+
Sbjct: 287 CESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYI 320



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 51/164 (31%), Positives = 71/164 (43%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCYGK 58
           G  C D+DEC+  + CQ+ +C+N  GS+ C+C P ++L  +  +C D  +    A C  +
Sbjct: 159 GPECVDIDECRY-RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQR 216

Query: 59  VDLRSGTETCR--DSDELSEDGTMAACC--CSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
                GT  CR     EL  DG   +    CS  +    Y C    EPG    R  C   
Sbjct: 217 CFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRC--VNEPG----RFSCHCP 270

Query: 114 PGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
            GYQ +           DIDEC +    C+   TC N  G + C
Sbjct: 271 QGYQLLA-----TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 49/179 (27%), Positives = 68/179 (37%), Gaps = 23/179 (12%)

Query: 34  CPPNYELVSDGTACYDSRKAR-----CYGKVDLRS--GTETCRDSDELSEDGTMAACCCS 86
           CPP YE   D  +C D  +       C    D  +  G+  C   D   + G     C  
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE---CVD 164

Query: 87  VGAAWGNYCDP-CPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH 144
           +      YC   C   PGS  +R  C   PG+Q  L P +   +  D++EC    G    
Sbjct: 165 IDECRYRYCQHRCVNLPGS--FRCQCE--PGFQ--LGPNNR--SCVDVNECDM--GAPCE 214

Query: 145 GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             C N++G+F+C C  G+ L                       C N PG + C CP+GY
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273


>AY004330-1|AAK11491.1|  493|Homo sapiens EGF-containing
           fibulin-like extracellular matrix protein 1 protein.
          Length = 493

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 56/216 (25%), Positives = 80/216 (37%), Gaps = 27/216 (12%)

Query: 6   CTDVDECKS-PQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR----CYGKV 59
           C D+DEC +   +C+  Q CIN +GS+ C+CPP Y+    G  C D  +      C+ + 
Sbjct: 171 CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQCVDIDECTIPPYCHQRC 228

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG 115
               G+  C+ S           C         N CD   +   + Y  L    C    G
Sbjct: 229 VNTPGSFYCQCSPGFQLAANNYTCVDI------NECDASNQCAQQCYNILGSFICQCNQG 282

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           Y    E  S  +   DIDEC     LC +  C N  G F C C  G+ +           
Sbjct: 283 Y----ELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQVVRSRTCQDINE 337

Query: 176 XXXRPDVCGPGVCRNLPGSYVCL----CPEGYVAMP 207
                +     +C N  G + C     C + Y+  P
Sbjct: 338 CETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTP 373



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA--------R 54
           G  C D+DEC  P  C + +C+NT GS+ C+C P ++L ++   C D  +         +
Sbjct: 209 GEQCVDIDECTIPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ 267

Query: 55  CYGKVDLRSGTETCRDSDELSEDGTMAACC--CSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
           CY    L S    C    ELS D         C   +    Y     EPG   +  +CP 
Sbjct: 268 CYN--ILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGK--FSCMCP- 321

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVC 156
             GYQ V        T  DI+EC           C N  G F C
Sbjct: 322 -QGYQVVRSR-----TCQDINECETTNECREDEMCWNYHGGFRC 359



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 57/217 (26%), Positives = 78/217 (35%), Gaps = 24/217 (11%)

Query: 6   CTDVDECKS-PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKAR-CYGKVDLR 62
           C D+DEC   P +C+ G +C+N  G Y C       +V++     +++ A    G     
Sbjct: 42  CKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGV 101

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWG----------NYCDPCPEPGSEAYRQLCPG 112
               +   S  L   G +A+     G              N  DP   P + ++R  C  
Sbjct: 102 VAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAA 161

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXX 171
           G       E   + V   DIDEC A    C A   C N  GSF C C  G+         
Sbjct: 162 G------YEQSEHNVC-QDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVD 214

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                   P  C    C N PGS+ C C  G+    N
Sbjct: 215 IDECTI--PPYCHQR-CVNTPGSFYCQCSPGFQLAAN 248


>AJ132819-1|CAA10791.2|  443|Homo sapiens fibulin-4 protein.
          Length = 443

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 27/214 (12%)

Query: 5   NCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR---CYGKV 59
           +C DVDEC ++   C+  Q C N  GSY C CP  Y  +  G  C D  + R   C  + 
Sbjct: 120 SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI--GPECVDIDECRYRYCQHRC 177

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQ-LCPGGPG 115
               G+  C+  +   + G     C  V     N CD   PC +    +Y   LC    G
Sbjct: 178 VNLPGSFRCQ-CEPGFQLGPNNRSCVDV-----NECDMGAPCEQRCFNSYGTFLCRCHQG 231

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           Y+  L    +  + +DIDEC+    LC +  C N  G F C C  G+ L           
Sbjct: 232 YE--LHRDGF--SCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGYQLLATRLCQDIDE 286

Query: 176 XXXRPDVCGPG-VCRNLPGSYVCL----CPEGYV 204
                  C     C N  G Y C+    C E Y+
Sbjct: 287 CESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYI 320



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 51/164 (31%), Positives = 71/164 (43%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCYGK 58
           G  C D+DEC+  + CQ+ +C+N  GS+ C+C P ++L  +  +C D  +    A C  +
Sbjct: 159 GPECVDIDECRY-RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQR 216

Query: 59  VDLRSGTETCR--DSDELSEDGTMAACC--CSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
                GT  CR     EL  DG   +    CS  +    Y C    EPG    R  C   
Sbjct: 217 CFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRC--VNEPG----RFSCHCP 270

Query: 114 PGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
            GYQ +           DIDEC +    C+   TC N  G + C
Sbjct: 271 QGYQLLA-----TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 49/179 (27%), Positives = 68/179 (37%), Gaps = 23/179 (12%)

Query: 34  CPPNYELVSDGTACYDSRKAR-----CYGKVDLRS--GTETCRDSDELSEDGTMAACCCS 86
           CPP YE   D  +C D  +       C    D  +  G+  C   D   + G     C  
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE---CVD 164

Query: 87  VGAAWGNYCDP-CPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH 144
           +      YC   C   PGS  +R  C   PG+Q  L P +   +  D++EC    G    
Sbjct: 165 IDECRYRYCQHRCVNLPGS--FRCQCE--PGFQ--LGPNNR--SCVDVNECDM--GAPCE 214

Query: 145 GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             C N++G+F+C C  G+ L                       C N PG + C CP+GY
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273


>AF525689-1|AAN77133.1|  988|Homo sapiens signal
           peptide-CUB-EGF-like domain containing protein 1
           protein.
          Length = 988

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 58/207 (28%), Positives = 76/207 (36%), Gaps = 21/207 (10%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVS---DGTACYDSRKARC-YGK 58
           G NC + D       C +      +G   C C P ++L     D T   +     C +  
Sbjct: 163 GMNCMNKDH-----GCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSC 217

Query: 59  VDLRSG-TETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
            D  +G T  C        DG      C+V       CD   +  +   R  CP G   Q
Sbjct: 218 EDTDTGPTCGCHQKYAPHSDGRTCIETCAVN---NGGCDRTCKDTATGVRCSCPVGFTLQ 274

Query: 118 PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
           P  +      T  DI+EC  + G C H  C NT GSF C C  G+ L             
Sbjct: 275 PDGK------TCKDINECLVNNGGCDH-FCRNTVGSFECGCRKGYKLLTDERTCQDIDEC 327

Query: 178 XRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                C   +C N PGS+ CLC  GY+
Sbjct: 328 SFERTCDH-ICINSPGSFQCLCHRGYI 353



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 59/211 (27%), Positives = 77/211 (36%), Gaps = 20/211 (9%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY--DSRKARCYGKVD 60
           G NC DVDEC+         C+N  GSY C+C   + L  +   C    +    C  K  
Sbjct: 112 GHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKD- 170

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPG---GP 114
                  CR   E  + G   AC C  G   A     C      G+   +  C     GP
Sbjct: 171 -HGCAHICR---ETPKGG--VACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGP 224

Query: 115 --GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
             G      P S   T   I+ CA + G C   TC +T     C+C  G++L P      
Sbjct: 225 TCGCHQKYAPHSDGRTC--IETCAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTCK 281

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                   +      CRN  GS+ C C +GY
Sbjct: 282 DINECLVNNGGCDHFCRNTVGSFECGCRKGY 312



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 57/195 (29%), Positives = 70/195 (35%), Gaps = 26/195 (13%)

Query: 18  CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSED 77
           CQ+  C +T    TC C   Y   SDG  C ++    C   V+      TC+D+      
Sbjct: 213 CQHS-CEDTDTGPTCGCHQKYAPHSDGRTCIET----C--AVNNGGCDRTCKDT------ 259

Query: 78  GTMAACCCSVGAAW---GNYCDPCPE--PGSEAYRQLCPGGPGYQPVLEPPSYVV----- 127
            T   C C VG      G  C    E    +      C    G         Y +     
Sbjct: 260 ATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDER 319

Query: 128 TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV 187
           T  DIDEC+  E  C H  C N+ GSF C C  G+ L                  C  G 
Sbjct: 320 TCQDIDECS-FERTCDH-ICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG- 376

Query: 188 CRNLPGSYVCLCPEG 202
           C N  GSY C+CP G
Sbjct: 377 CVNTKGSYECVCPPG 391



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/60 (41%), Positives = 32/60 (53%), Gaps = 2/60 (3%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           +C DVDEC  S  SC  G C+NT+GSY C CPP   L  +   C ++ K     K   R+
Sbjct: 359 HCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNRKDCVETGKCLSRAKTSPRA 417



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 34/119 (28%), Positives = 44/119 (36%), Gaps = 7/119 (5%)

Query: 96  DPCPEPGSEAYRQ-LCPGGPGYQPVLEPPSYV---VTLADIDECAA--HEGLCAHGTCTN 149
           D C E   + +   +C   P     L  P Y        DIDEC    + G C H  C N
Sbjct: 35  DECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGEGKQCGDIDECENDYYNGGCVH-ECIN 93

Query: 150 TFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
             G++ CTC  G+ LA               +     +C N  GSY C C  G+    N
Sbjct: 94  IPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDN 152



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 4/50 (8%)

Query: 3   GFNCTDVDECKSPQ---SCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G  C D+DEC++      C + +CIN  G+Y C C   + L  DG  C D
Sbjct: 69  GKQCGDIDECENDYYNGGCVH-ECINIPGNYRCTCFDGFMLAHDGHNCLD 117



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 2/44 (4%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           C D+DEC   ++C +  CIN+ GS+ C C   Y L    T C D
Sbjct: 321 CQDIDECSFERTCDH-ICINSPGSFQCLCHRGYILYGT-THCGD 362



 Score = 31.9 bits (69), Expect = 1.9
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 6/51 (11%)

Query: 1  MPGFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYD 49
          +PG    DVDEC +    C     C N   SY C C P Y+   +G  C D
Sbjct: 28 LPG--SVDVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYK--GEGKQCGD 74


>AF109121-1|AAF65188.1|  443|Homo sapiens EGF-containing
           fibulin-like extracellular matrix protein 2 protein.
          Length = 443

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 27/214 (12%)

Query: 5   NCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR---CYGKV 59
           +C DVDEC ++   C+  Q C N  GSY C CP  Y  +  G  C D  + R   C  + 
Sbjct: 120 SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI--GPECVDIDECRYRYCQHRC 177

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQ-LCPGGPG 115
               G+  C+  +   + G     C  V     N CD   PC +    +Y   LC    G
Sbjct: 178 VNLPGSFRCQ-CEPGFQLGPNNRSCVDV-----NECDMGAPCEQRCFNSYGTFLCRCHQG 231

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           Y+  L    +  + +DIDEC+    LC +  C N  G F C C  G+ L           
Sbjct: 232 YE--LHRDGF--SCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGYQLLATRLCQDIDE 286

Query: 176 XXXRPDVCGPG-VCRNLPGSYVCL----CPEGYV 204
                  C     C N  G Y C+    C E Y+
Sbjct: 287 CESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYI 320



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 51/164 (31%), Positives = 71/164 (43%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCYGK 58
           G  C D+DEC+  + CQ+ +C+N  GS+ C+C P ++L  +  +C D  +    A C  +
Sbjct: 159 GPECVDIDECRY-RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQR 216

Query: 59  VDLRSGTETCR--DSDELSEDGTMAACC--CSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
                GT  CR     EL  DG   +    CS  +    Y C    EPG    R  C   
Sbjct: 217 CFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRC--VNEPG----RFSCHCP 270

Query: 114 PGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
            GYQ +           DIDEC +    C+   TC N  G + C
Sbjct: 271 QGYQLLA-----TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 49/179 (27%), Positives = 68/179 (37%), Gaps = 23/179 (12%)

Query: 34  CPPNYELVSDGTACYDSRKAR-----CYGKVDLRS--GTETCRDSDELSEDGTMAACCCS 86
           CPP YE   D  +C D  +       C    D  +  G+  C   D   + G     C  
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE---CVD 164

Query: 87  VGAAWGNYCDP-CPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH 144
           +      YC   C   PGS  +R  C   PG+Q  L P +   +  D++EC    G    
Sbjct: 165 IDECRYRYCQHRCVNLPGS--FRCQCE--PGFQ--LGPNNR--SCVDVNECDM--GAPCE 214

Query: 145 GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             C N++G+F+C C  G+ L                       C N PG + C CP+GY
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273


>AB209212-1|BAD92449.1|  418|Homo sapiens EGF-containing
           fibulin-like extracellular matrix protein 1 isoform b
           variant protein.
          Length = 418

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 56/216 (25%), Positives = 80/216 (37%), Gaps = 27/216 (12%)

Query: 6   CTDVDECKS-PQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR----CYGKV 59
           C D+DEC +   +C+  Q CIN +GS+ C+CPP Y+    G  C D  +      C+ + 
Sbjct: 96  CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQCVDIDECTIPPYCHQRC 153

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPG 115
               G+  C+ S           C         N CD   +   + Y  L    C    G
Sbjct: 154 VNTPGSFYCQCSPGFQLAANNYTCVDI------NECDASNQCAQQCYNILGSFICQCNQG 207

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           Y    E  S  +   DIDEC     LC +  C N  G F C C  G+ +           
Sbjct: 208 Y----ELSSDRLNCEDIDECRTSSYLCQY-QCVNQPGKFSCMCPQGYQVVRSRTCQDINE 262

Query: 176 XXXRPDVCGPGVCRNLPGSYVCL----CPEGYVAMP 207
                +     +C N  G + C     C + Y+  P
Sbjct: 263 CETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTP 298



 Score = 57.2 bits (132), Expect = 4e-08
 Identities = 48/164 (29%), Positives = 65/164 (39%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA--------R 54
           G  C D+DEC  P  C + +C+NT GS+ C+C P ++L ++   C D  +         +
Sbjct: 134 GEQCVDIDECTIPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ 192

Query: 55  CYGKVDLRSGTETCRDSDELSEDGTMAACC--CSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
           CY    L S    C    ELS D         C   +    Y     +PG   +  +CP 
Sbjct: 193 CYN--ILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNQPGK--FSCMCP- 246

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVC 156
             GYQ V        T  DI+EC           C N  G F C
Sbjct: 247 -QGYQVVRSR-----TCQDINECETTNECREDEMCWNYHGGFRC 284



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 36/117 (30%), Positives = 43/117 (36%), Gaps = 11/117 (9%)

Query: 93  NYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTF 151
           N  DP   P + ++R  C  G       E   + V   DIDEC A    C A   C N  
Sbjct: 67  NPADPQRIPSNPSHRIQCAAG------YEQSEHNVC-QDIDECTAGTHNCRADQVCINLR 119

Query: 152 GSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
           GSF C C  G+                 P  C    C N PGS+ C C  G+    N
Sbjct: 120 GSFACQCPPGYQKRGEQCVDIDECTI--PPYCHQR-CVNTPGSFYCQCSPGFQLAAN 173


>AB209121-1|BAD92358.1|  620|Homo sapiens Mutant p53 binding protein
           1 variant protein.
          Length = 620

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 55/211 (26%), Positives = 79/211 (37%), Gaps = 14/211 (6%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRS 63
           +C DV+EC     C+  +C N+ G++ CRC   YEL  DG +C  +S     Y  VD ++
Sbjct: 290 SCVDVNECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSGESSIPAVYSSVDPQA 348

Query: 64  GTETCRDSDELSEDGTMAACC---CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY--QP 118
               C        + + +  C   C +G       +     G    R        Y   P
Sbjct: 349 LAMPCLLPHSSPFEASASCHCAPSCLLGTRPRLAVEHSQASGGGTRRGSYVLTEAYWGMP 408

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           +   P +    +DIDEC+    LC +  C N  G F C C  G+ L              
Sbjct: 409 LTRGP-HPHASSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGYQLLATRLCQDIDECES 466

Query: 179 RPDVCGPG-VCRNLPGSYVCL----CPEGYV 204
               C     C N  G Y C+    C E Y+
Sbjct: 467 GAHQCSEAQTCVNFHGGYRCVDTNRCVEPYI 497



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 54/206 (26%), Positives = 80/206 (38%), Gaps = 19/206 (9%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCYGKVDLRS 63
           D+DEC+  + CQ+ +C+N  GS+ C+C P ++L  +  +C D  +    A C  +     
Sbjct: 254 DIDECRY-RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSY 311

Query: 64  GTETCR--DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
           GT  CR     EL  DG   +   S+ A + +      +P + A   L P    ++    
Sbjct: 312 GTFLCRCHQGYELHRDGFSCSGESSIPAVYSSV-----DPQALAMPCLLPHSSPFEASAS 366

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL----APXXXXXXXXXXX 177
                  L       A E   A G  T   GS+V T  A W +     P           
Sbjct: 367 CHCAPSCLLGTRPRLAVEHSQASGGGTRR-GSYVLT-EAYWGMPLTRGPHPHASSDIDEC 424

Query: 178 XRPDVCGPGVCRNLPGSYVCLCPEGY 203
                     C N PG + C CP+GY
Sbjct: 425 SYSSYLCQYRCVNEPGRFSCHCPQGY 450



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 8/90 (8%)

Query: 118 PVLEP-PSYVVTLA---DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
           P L P PS ++ L    DIDEC      C H  C N  GSF C C  G+ L P       
Sbjct: 237 PALCPLPSALLLLPLSLDIDECRYR--YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVD 293

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                    C    C N  G+++C C +GY
Sbjct: 294 VNECDMGAPCEQR-CFNSYGTFLCRCHQGY 322



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 6/56 (10%)

Query: 6   CTDVDECKS-PQSCQYGQ-CINTQGSYTC----RCPPNYELVSDGTACYDSRKARC 55
           C D+DEC+S    C   Q C+N  G Y C    RC   Y  VS+      +    C
Sbjct: 458 CQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLC 513


>AB030655-1|BAA92880.1|  443|Homo sapiens mutant p53 binding protein
           1 (MBP1) protein.
          Length = 443

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 27/214 (12%)

Query: 5   NCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR---CYGKV 59
           +C DVDEC ++   C+  Q C N  GSY C CP  Y  +  G  C D  + R   C  + 
Sbjct: 120 SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI--GPECVDIDECRYRYCQHRC 177

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQ-LCPGGPG 115
               G+  C+  +   + G     C  V     N CD   PC +    +Y   LC    G
Sbjct: 178 VNLPGSFRCQ-CEPGFQLGPNNRSCVDV-----NECDMGAPCEQRCFNSYGTFLCRCHQG 231

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           Y+  L    +  + +DIDEC+    LC +  C N  G F C C  G+ L           
Sbjct: 232 YE--LHRDGF--SCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGYQLLATRLCQDIDE 286

Query: 176 XXXRPDVCGPG-VCRNLPGSYVCL----CPEGYV 204
                  C     C N  G Y C+    C E Y+
Sbjct: 287 CESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYI 320



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 51/164 (31%), Positives = 71/164 (43%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCYGK 58
           G  C D+DEC+  + CQ+ +C+N  GS+ C+C P ++L  +  +C D  +    A C  +
Sbjct: 159 GPECVDIDECRY-RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQR 216

Query: 59  VDLRSGTETCR--DSDELSEDGTMAACC--CSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
                GT  CR     EL  DG   +    CS  +    Y C    EPG    R  C   
Sbjct: 217 CFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRC--VNEPG----RFSCHCP 270

Query: 114 PGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
            GYQ +           DIDEC +    C+   TC N  G + C
Sbjct: 271 QGYQLLA-----TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 49/179 (27%), Positives = 68/179 (37%), Gaps = 23/179 (12%)

Query: 34  CPPNYELVSDGTACYDSRKAR-----CYGKVDLRS--GTETCRDSDELSEDGTMAACCCS 86
           CPP YE   D  +C D  +       C    D  +  G+  C   D   + G     C  
Sbjct: 109 CPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE---CVD 164

Query: 87  VGAAWGNYCDP-CPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH 144
           +      YC   C   PGS  +R  C   PG+Q  L P +   +  D++EC    G    
Sbjct: 165 IDECRYRYCQHRCVNLPGS--FRCQCE--PGFQ--LGPNNR--SCVDVNECDM--GAPCE 214

Query: 145 GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             C N++G+F+C C  G+ L                       C N PG + C CP+GY
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273


>AJ295142-1|CAC82720.1|  652|Homo sapiens C1q receptor protein
           protein.
          Length = 652

 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 63/201 (31%), Positives = 76/201 (37%), Gaps = 36/201 (17%)

Query: 28  GSYTCRCPPNYELVSDGTACYDSR---KARCYGKVDLRSGTE----TCRDSDELSEDGTM 80
           GS+ C C P + L+ D   C        + C G      G      TCR       D + 
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHGKNYTCRCPQGYQLDSSQ 340

Query: 81  AACCCSVGAAWGNYC-DPCPE-PGS---EAYRQLCPGGPGYQPVLEPPSYVVTLADIDEC 135
             C   V     + C   C   PG    E +    PGGPG               D+DEC
Sbjct: 341 LDCV-DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEG----------ACQDVDEC 389

Query: 136 AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GPG------VC 188
           A     CA G CTNT GSF C+C  G+ LA               D C GPG      +C
Sbjct: 390 ALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDV-----DECVGPGGPLCDSLC 443

Query: 189 RNLPGSYVCLCPEGYVAMPNG 209
            N  GS+ C C  G+V  PNG
Sbjct: 444 FNTQGSFHCGCLPGWVLAPNG 464



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 52/179 (29%), Positives = 63/179 (35%), Gaps = 19/179 (10%)

Query: 2   PGFNCTD-VDECKSPQSCQYGQC-------INTQG-SYTCRCPPNYELVSDGTACYD--- 49
           PGF   D +  C S   C    C       +   G +YTCRCP  Y+L S    C D   
Sbjct: 289 PGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHGKNYTCRCPQGYQLDSSQLDCVDVDE 348

Query: 50  SRKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVG-AAWGNYCDPCPEPGSEAYRQ 108
            + + C  +     G   C         G     C  V   A G    PC +  +     
Sbjct: 349 CQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGR--SPCAQGCTNTDGS 406

Query: 109 L-CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
             C    GY    E  +      D+DEC    G      C NT GSF C C  GW LAP
Sbjct: 407 FHCSCEEGYVLAGEDGT---QCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAP 462



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G  C DVDEC  P    C    C NTQGS+ C C P + L  +G +C
Sbjct: 422 GTQCQDVDECVGPGGPLCD-SLCFNTQGSFHCGCLPGWVLAPNGVSC 467



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 19/71 (26%), Positives = 24/71 (33%), Gaps = 2/71 (2%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLP-- 192
           C  + G C         GSF+C C  G+ L                   G   C   P  
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHG 323

Query: 193 GSYVCLCPEGY 203
            +Y C CP+GY
Sbjct: 324 KNYTCRCPQGY 334


>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
          Length = 2444

 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 61/211 (28%), Positives = 89/211 (42%), Gaps = 34/211 (16%)

Query: 3   GFNC-TDVDECKSPQSCQY-GQCINTQGSYTCRC-----PPNYELVSDGTACYDSRKARC 55
           G +C T+++EC S Q C+  G C +   +Y C C      PN E+  D  A        C
Sbjct: 597 GHHCETNINECSS-QPCRLRGTCQDPDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTC 655

Query: 56  YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQLCPG 112
             K+D   G E C  + E    G+M  C  ++    GN C     C E G   +   CP 
Sbjct: 656 LDKID---GYE-C--ACEPGYTGSM--CNSNIDECAGNPCHNGGTC-EDGINGFTCRCP- 705

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
             GY    +P      L++++EC ++   C HG C ++   + C C  GWS         
Sbjct: 706 -EGYH---DP----TCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGWS--GTNCDIN 753

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P V G G C+++    VC C EG+
Sbjct: 754 NNECESNPCVNG-GTCKDMTSGIVCTCREGF 783



 Score = 59.7 bits (138), Expect = 8e-09
 Identities = 58/209 (27%), Positives = 76/209 (36%), Gaps = 23/209 (11%)

Query: 3   GFNCT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           G  CT DVDEC+  P +CQ G  C NT G Y C C   +          D   A C+   
Sbjct: 289 GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGA 348

Query: 60  DLRSGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
                  +          G +      C S     G+ CD  P  G    + +C    GY
Sbjct: 349 TCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNG----KAICTCPSGY 404

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                 P+      D+DEC+     C H G C NT GSF C C  G++  P         
Sbjct: 405 TG----PA---CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT-GPRCEIDVNEC 456

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                + C     C +  G + C+C  GY
Sbjct: 457 VS---NPCQNDATCLDQIGEFQCMCMPGY 482



 Score = 57.2 bits (132), Expect = 4e-08
 Identities = 57/208 (27%), Positives = 80/208 (38%), Gaps = 29/208 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  D+DEC  P  C YG C +   ++TC C P Y     G  C ++    C  +   
Sbjct: 560 GTHCEVDIDEC-DPDPCHYGSCKDGVATFTCLCRPGY----TGHHC-ETNINECSSQPCR 613

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQP 118
             G  TC+D D          C C  G    N     D C     ++   L     GY+ 
Sbjct: 614 LRG--TCQDPD------NAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCL-DKIDGYEC 664

Query: 119 VLEPPSYVVTL--ADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E P Y  ++  ++IDECA +   C + GTC +    F C C  G+             
Sbjct: 665 ACE-PGYTGSMCNSNIDECAGNP--CHNGGTCEDGINGFTCRCPEGY----HDPTCLSEV 717

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                + C  G CR+    Y C C  G+
Sbjct: 718 NECNSNPCVHGACRDSLNGYKCDCDPGW 745



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 55/204 (26%), Positives = 77/204 (37%), Gaps = 26/204 (12%)

Query: 8   DVDEC-KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           DV+EC + P+ C++G  C N  GSY C C   +     G  C +     C        GT
Sbjct: 178 DVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHT----GPNC-ERPYVPCSPSPCQNGGT 232

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQ-LCPGGPGYQPVLEP 122
             CR + +++ +     C C  G   G  C+   +  PG+       C  G        P
Sbjct: 233 --CRPTGDVTHE-----CACLPGFT-GQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCP 284

Query: 123 PSYV--VTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
           P +       D+DEC      C +G TC NT G + C C  GW+                
Sbjct: 285 PEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASA-- 342

Query: 180 PDVCGPG-VCRNLPGSYVCLCPEG 202
              C  G  C +   S+ C CP G
Sbjct: 343 --ACFHGATCHDRVASFYCECPHG 364



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 60/214 (28%), Positives = 77/214 (35%), Gaps = 29/214 (13%)

Query: 3    GFNC-TDVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            G  C  D++EC  SP  C++G  C NT G Y C C   Y   +  T   D R   C+   
Sbjct: 864  GQTCEVDINECVLSP--CRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGG 921

Query: 60   DLRSGTETCRDSDELSEDGTMAA----CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG-P 114
                G  T          GT        C S     G  C  C     ++Y   CP G  
Sbjct: 922  SCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDC----VDSYTCTCPAGFS 977

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
            G       P       D  E +   G    GTC +   SF C C  G++           
Sbjct: 978  GIHCENNTP-------DCTESSCFNG----GTCVDGINSFTCLCPPGFT--GSYCQHVVN 1024

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                RP + G G C++  G + C CP+GY   PN
Sbjct: 1025 ECDSRPCLLG-GTCQDGRGLHRCTCPQGYTG-PN 1056



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 52/202 (25%), Positives = 77/202 (38%), Gaps = 28/202 (13%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           DV+EC S        C++  G + C C P YE    G  C +     C     L +G   
Sbjct: 452 DVNECVSNPCQNDATCLDQIGEFQCMCMPGYE----GVHC-EVNTDECASSPCLHNG--- 503

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQPVLEPP 123
            R  D+++E      C C  G   G+ C    D C     +   + C  GP     +   
Sbjct: 504 -RCLDKINE----FQCECPTGFT-GHLCQYDVDECASTPCKNGAK-CLDGPNTYTCVCTE 556

Query: 124 SYVVT--LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
            Y  T    DIDEC      C +G+C +   +F C C  G++               +P 
Sbjct: 557 GYTGTHCEVDIDECDPDP--CHYGSCKDGVATFTCLCRPGYT--GHHCETNINECSSQP- 611

Query: 182 VCG-PGVCRNLPGSYVCLCPEG 202
            C   G C++   +Y+C C +G
Sbjct: 612 -CRLRGTCQDPDNAYLCFCLKG 632



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 57/218 (26%), Positives = 76/218 (34%), Gaps = 26/218 (11%)

Query: 3    GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC + V  C S      G+C  T   Y C CP  +     G  C D     C      
Sbjct: 1054 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT----GLYC-DVPSVSCEVAAQ- 1107

Query: 62   RSGTET---CRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEAYRQLCPGG 113
            R G +    C+      + G    C C  G   G+YC    D C P P           G
Sbjct: 1108 RQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT-GSYCEDLVDECSPSPCQNGATCTDYLG 1166

Query: 114  PGYQPVLEPPSYVVTLAD-IDECAAHEGLCAHG-TCTNTFGSFVCTC-----GAGWSLAP 166
             GY        + V  ++ IDEC +H   C +G TC +   ++ C+C     G    +  
Sbjct: 1167 -GYSCKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQGVHCEINV 1223

Query: 167  XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                         P     G C +  G Y C CP G+V
Sbjct: 1224 DDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1261



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 51/171 (29%), Positives = 66/171 (38%), Gaps = 31/171 (18%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  ++D+C S   C  G C++    Y C C P Y     G+ C +S    C G    
Sbjct: 635 GPNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGYT----GSMC-NSNIDECAGNPCH 688

Query: 62  RSGTETCRDSDELSEDGTMAACC-CSVGAAWGNYCDP-CPEPGSEAYRQLCPGGP----- 114
             GT  C       EDG     C C  G     Y DP C    +E     C  G      
Sbjct: 689 NGGT--C-------EDGINGFTCRCPEG-----YHDPTCLSEVNECNSNPCVHGACRDSL 734

Query: 115 -GYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWS 163
            GY+   +P  +  T  DI+        C +G TC +     VCTC  G+S
Sbjct: 735 NGYKCDCDP-GWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFS 784



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 61/218 (27%), Positives = 78/218 (35%), Gaps = 43/218 (19%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC T+++EC S      G CI+    Y C C   Y     G  C +   A C      
Sbjct: 785 GPNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPY----TGATC-EVVLAPC-APSPC 838

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGS-----EAYR 107
           R+G E CR     SED    +C C    A G  C+         PC    S       YR
Sbjct: 839 RNGGE-CRQ----SEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYR 893

Query: 108 QLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAP 166
             C    GY       S      DID+C  +   C + G+CT+   +  C C  G+    
Sbjct: 894 CHCQA--GY-------SGRNCETDIDDCRPNP--CHNGGSCTDGINTAFCDCLPGF---- 938

Query: 167 XXXXXXXXXXXXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
                         D C  G  C +   SY C CP G+
Sbjct: 939 RGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGF 976



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 54/213 (25%), Positives = 80/213 (37%), Gaps = 30/213 (14%)

Query: 3    GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G NC TD+D+C+ P  C  G  C +   +  C C P +     GT C +     C     
Sbjct: 902  GRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDIN-EC----- 950

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQ-LCPGGPG 115
                ++ CR+    ++      C C  G + G +C+     C E  S  +    C  G  
Sbjct: 951  ---ASDPCRNGANCTDCVDSYTCTCPAGFS-GIHCENNTPDCTE--SSCFNGGTCVDGIN 1004

Query: 116  YQPVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                L PP +  +     ++EC +   L   GTC +  G   CTC  G++  P       
Sbjct: 1005 SFTCLCPPGFTGSYCQHVVNECDSRPCLLG-GTCQDGRGLHRCTCPQGYT-GPNCQNLVH 1062

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
                  P   G G C      Y C CP G+  +
Sbjct: 1063 WCDSS-PCKNG-GKCWQTHTQYRCECPSGWTGL 1093



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/212 (24%), Positives = 74/212 (34%), Gaps = 29/212 (13%)

Query: 3    GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC++ +DEC S      G C++   +Y C CP      + G  C +     C   VD 
Sbjct: 1178 GVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRG----TQGVHC-EINVDDCNPPVDP 1232

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGSEAYRQL--- 109
             S +  C ++    +     +C C  G   G  C+         PC   G++   Q    
Sbjct: 1233 VSRSPKCFNNGTCVDQVGGYSCTCPPGFV-GERCEGDVNECLSNPCDARGTQNCVQRVND 1291

Query: 110  --CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPX 167
              C    G+         V+       C  + G CA    +NT   F+C C AG+  A  
Sbjct: 1292 FHCECRAGHTG--RRCESVINGCKGKPC-KNGGTCA--VASNTARGFICKCPAGFEGATC 1346

Query: 168  XXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                              G C + P S  CLC
Sbjct: 1347 ENDARTCGSLR---CLNGGTCISGPRSPTCLC 1375



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 52/216 (24%), Positives = 77/216 (35%), Gaps = 30/216 (13%)

Query: 1   MPGF---NCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF   NC + +D+C        G C++   +Y C CPP +     G  C +     C 
Sbjct: 246 LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPEW----TGQYCTED-VDECQ 300

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGPG 115
              +      TC +    +  G    C C  G  W    + C E   +     C  G   
Sbjct: 301 LMPNACQNGGTCHN----THGG--YNCVCVNG--WTG--EDCSENIDDCASAACFHGATC 350

Query: 116 YQPVLE-----PPSYVVTLADIDECAAHEGLCAHGT-C-TNTF-GSFVCTCGAGWSLAPX 167
           +  V       P      L  +++ A     C  G+ C TN   G  +CTC +G++  P 
Sbjct: 351 HDRVASFYCECPHGRTGLLCHLND-ACISNPCNEGSNCDTNPVNGKAICTCPSGYT-GPA 408

Query: 168 XXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                             G C N  GS+ C C +GY
Sbjct: 409 CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY 444



 Score = 34.7 bits (76), Expect = 0.27
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 8/73 (10%)

Query: 133 DECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV-CRN 190
           DECA+    C H G C +    F C C  G++                P  C  G  C +
Sbjct: 492 DECASSP--CLHNGRCLDKINEFQCECPTGFT--GHLCQYDVDECASTP--CKNGAKCLD 545

Query: 191 LPGSYVCLCPEGY 203
            P +Y C+C EGY
Sbjct: 546 GPNTYTCVCTEGY 558


>L13720-1|AAA58494.1|  678|Homo sapiens growth-arrest-specific
           protein protein.
          Length = 678

 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 1/73 (1%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D++EC+   G C    C N  GSF C+C +G+ L+               + CG   C+N
Sbjct: 156 DVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKN 214

Query: 191 LPGSYVCLCPEGY 203
           LPGSY CLC EG+
Sbjct: 215 LPGSYSCLCDEGF 227



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 55/190 (28%), Positives = 67/190 (35%), Gaps = 27/190 (14%)

Query: 19  QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDG 78
           +Y  CIN  GS        Y   S    C  +   +C      R GT+ C+D        
Sbjct: 91  RYLDCINKYGS-------PYTKNSGFATCVQNLPDQCTPNPCDRKGTQACQD-------- 135

Query: 79  TMAACCCSVGAAWGN-YCDPCPEPGSE---AYRQLCPGGPGY-----QPVLEPPSYVVTL 129
            M    C   A WG   CD      S+      Q+C   PG          E  S   T 
Sbjct: 136 LMGNFFCLCKAGWGGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTC 195

Query: 130 ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
            DIDECA  E  C    C N  GS+ C C  G++ +             +   C   VC 
Sbjct: 196 QDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR-CEQ-VCV 252

Query: 190 NLPGSYVCLC 199
           N PGSY C C
Sbjct: 253 NSPGSYTCHC 262



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCYGKV 59
           G  C D+DEC   ++C   +C N  GSY+C C   +   S   AC D     + RC    
Sbjct: 192 GRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRCEQVC 251

Query: 60  DLRSGTETC 68
               G+ TC
Sbjct: 252 VNSPGSYTC 260



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 31/111 (27%), Positives = 45/111 (40%), Gaps = 13/111 (11%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           DV+EC          C N  GS+ C C   +EL SDG  C D         +D  + +E 
Sbjct: 156 DVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQD---------IDECADSEA 206

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGNY---CDPCPEPGSEAYRQLCPGGPG 115
           C ++   +  G+  +C C  G A+ +    C    E       Q+C   PG
Sbjct: 207 CGEARCKNLPGSY-SCLCDEGFAYSSQEKACRDVDECLQGRCEQVCVNSPG 256



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 4/46 (8%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCP--PNYELVSDGTACYD 49
           C DVDEC   +  Q   C+N+ GSYTC C      +L  D   C D
Sbjct: 236 CRDVDECLQGRCEQV--CVNSPGSYTCHCDGRGGLKLSQDMDTCED 279



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 17/63 (26%), Positives = 25/63 (39%), Gaps = 3/63 (4%)

Query: 147 CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           C +  G+F C C AGW                + +     +C N PGS+ C C  G+   
Sbjct: 133 CQDLMGNFFCLCKAGWG---GRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELS 189

Query: 207 PNG 209
            +G
Sbjct: 190 SDG 192


>BX072579-3|CAH71174.1|  678|Homo sapiens growth arrest-specific 6
           protein.
          Length = 678

 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 1/73 (1%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D++EC+   G C    C N  GSF C+C +G+ L+               + CG   C+N
Sbjct: 156 DVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKN 214

Query: 191 LPGSYVCLCPEGY 203
           LPGSY CLC EG+
Sbjct: 215 LPGSYSCLCDEGF 227



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 55/190 (28%), Positives = 67/190 (35%), Gaps = 27/190 (14%)

Query: 19  QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDG 78
           +Y  CIN  GS        Y   S    C  +   +C      R GT+ C+D        
Sbjct: 91  RYLDCINKYGS-------PYTKNSGFATCVQNLPDQCTPNPCDRKGTQACQD-------- 135

Query: 79  TMAACCCSVGAAWGN-YCDPCPEPGSE---AYRQLCPGGPGY-----QPVLEPPSYVVTL 129
            M    C   A WG   CD      S+      Q+C   PG          E  S   T 
Sbjct: 136 LMGNFFCLCKAGWGGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTC 195

Query: 130 ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
            DIDECA  E  C    C N  GS+ C C  G++ +             +   C   VC 
Sbjct: 196 QDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR-CEQ-VCV 252

Query: 190 NLPGSYVCLC 199
           N PGSY C C
Sbjct: 253 NSPGSYTCHC 262



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCYGKV 59
           G  C D+DEC   ++C   +C N  GSY+C C   +   S   AC D     + RC    
Sbjct: 192 GRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRCEQVC 251

Query: 60  DLRSGTETC 68
               G+ TC
Sbjct: 252 VNSPGSYTC 260



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 31/111 (27%), Positives = 45/111 (40%), Gaps = 13/111 (11%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           DV+EC          C N  GS+ C C   +EL SDG  C D         +D  + +E 
Sbjct: 156 DVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQD---------IDECADSEA 206

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGNY---CDPCPEPGSEAYRQLCPGGPG 115
           C ++   +  G+  +C C  G A+ +    C    E       Q+C   PG
Sbjct: 207 CGEARCKNLPGSY-SCLCDEGFAYSSQEKACRDVDECLQGRCEQVCVNSPG 256



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 4/46 (8%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCP--PNYELVSDGTACYD 49
           C DVDEC   +  Q   C+N+ GSYTC C      +L  D   C D
Sbjct: 236 CRDVDECLQGRCEQV--CVNSPGSYTCHCDGRGGLKLSQDMDTCED 279



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 17/63 (26%), Positives = 25/63 (39%), Gaps = 3/63 (4%)

Query: 147 CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           C +  G+F C C AGW                + +     +C N PGS+ C C  G+   
Sbjct: 133 CQDLMGNFFCLCKAGWG---GRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELS 189

Query: 207 PNG 209
            +G
Sbjct: 190 SDG 192


>BC038984-1|AAH38984.1|  678|Homo sapiens growth arrest-specific 6
           protein.
          Length = 678

 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 1/73 (1%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D++EC+   G C    C N  GSF C+C +G+ L+               + CG   C+N
Sbjct: 156 DVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKN 214

Query: 191 LPGSYVCLCPEGY 203
           LPGSY CLC EG+
Sbjct: 215 LPGSYSCLCDEGF 227



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 55/190 (28%), Positives = 67/190 (35%), Gaps = 27/190 (14%)

Query: 19  QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDG 78
           +Y  CIN  GS        Y   S    C  +   +C      R GT+ C+D        
Sbjct: 91  RYLDCINKYGS-------PYTKNSGFATCVQNLPDQCTPNPCDRKGTQACQD-------- 135

Query: 79  TMAACCCSVGAAWGN-YCDPCPEPGSE---AYRQLCPGGPGY-----QPVLEPPSYVVTL 129
            M    C   A WG   CD      S+      Q+C   PG          E  S   T 
Sbjct: 136 LMGNFFCLCKAGWGGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTC 195

Query: 130 ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
            DIDECA  E  C    C N  GS+ C C  G++ +             +   C   VC 
Sbjct: 196 QDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR-CEQ-VCV 252

Query: 190 NLPGSYVCLC 199
           N PGSY C C
Sbjct: 253 NSPGSYTCHC 262



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCYGKV 59
           G  C D+DEC   ++C   +C N  GSY+C C   +   S   AC D     + RC    
Sbjct: 192 GRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRCEQVC 251

Query: 60  DLRSGTETC 68
               G+ TC
Sbjct: 252 VNSPGSYTC 260



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 31/111 (27%), Positives = 45/111 (40%), Gaps = 13/111 (11%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           DV+EC          C N  GS+ C C   +EL SDG  C D         +D  + +E 
Sbjct: 156 DVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQD---------IDECADSEA 206

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGNY---CDPCPEPGSEAYRQLCPGGPG 115
           C ++   +  G+  +C C  G A+ +    C    E       Q+C   PG
Sbjct: 207 CGEARCKNLPGSY-SCLCDEGFAYSSQEKACRDVDECLQGRCEQVCVNSPG 256



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 4/46 (8%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCP--PNYELVSDGTACYD 49
           C DVDEC   +  Q   C+N+ GSYTC C      +L  D   C D
Sbjct: 236 CRDVDECLQGRCEQV--CVNSPGSYTCHCDGRGGLKLSQDMDTCED 279



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 17/63 (26%), Positives = 25/63 (39%), Gaps = 3/63 (4%)

Query: 147 CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           C +  G+F C C AGW                + +     +C N PGS+ C C  G+   
Sbjct: 133 CQDLMGNFFCLCKAGWG---GRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELS 189

Query: 207 PNG 209
            +G
Sbjct: 190 SDG 192


>AY256843-1|AAO84057.1|  678|Homo sapiens growth arrested-specific 6
           protein.
          Length = 678

 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 1/73 (1%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D++EC+   G C    C N  GSF C+C +G+ L+               + CG   C+N
Sbjct: 156 DVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKN 214

Query: 191 LPGSYVCLCPEGY 203
           LPGSY CLC EG+
Sbjct: 215 LPGSYSCLCDEGF 227



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 55/190 (28%), Positives = 67/190 (35%), Gaps = 27/190 (14%)

Query: 19  QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDG 78
           +Y  CIN  GS        Y   S    C  +   +C      R GT+ C+D        
Sbjct: 91  RYLDCINKYGS-------PYTKNSGFATCVQNLPDQCTPNPCDRKGTQACQD-------- 135

Query: 79  TMAACCCSVGAAWGN-YCDPCPEPGSE---AYRQLCPGGPGY-----QPVLEPPSYVVTL 129
            M    C   A WG   CD      S+      Q+C   PG          E  S   T 
Sbjct: 136 LMGNFFCLCKAGWGGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTC 195

Query: 130 ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
            DIDECA  E  C    C N  GS+ C C  G++ +             +   C   VC 
Sbjct: 196 QDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR-CEQ-VCV 252

Query: 190 NLPGSYVCLC 199
           N PGSY C C
Sbjct: 253 NSPGSYTCHC 262



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCYGKV 59
           G  C D+DEC   ++C   +C N  GSY+C C   +   S   AC D     + RC    
Sbjct: 192 GRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRCEQVC 251

Query: 60  DLRSGTETC 68
               G+ TC
Sbjct: 252 VNSPGSYTC 260



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 31/111 (27%), Positives = 45/111 (40%), Gaps = 13/111 (11%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           DV+EC          C N  GS+ C C   +EL SDG  C D         +D  + +E 
Sbjct: 156 DVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQD---------IDECADSEA 206

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGNY---CDPCPEPGSEAYRQLCPGGPG 115
           C ++   +  G+  +C C  G A+ +    C    E       Q+C   PG
Sbjct: 207 CGEARCKNLPGSY-SCLCDEGFAYSSQEKACRDVDECLQGRCEQVCVNSPG 256



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 4/46 (8%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCP--PNYELVSDGTACYD 49
           C DVDEC   +  Q   C+N+ GSYTC C      +L  D   C D
Sbjct: 236 CRDVDECLQGRCEQV--CVNSPGSYTCHCDGRGGLKLSQDMDTCED 279



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 17/63 (26%), Positives = 25/63 (39%), Gaps = 3/63 (4%)

Query: 147 CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           C +  G+F C C AGW                + +     +C N PGS+ C C  G+   
Sbjct: 133 CQDLMGNFFCLCKAGWG---GRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELS 189

Query: 207 PNG 209
            +G
Sbjct: 190 SDG 192


>AK126533-1|BAC86580.1|  624|Homo sapiens protein ( Homo sapiens
           cDNA FLJ44569 fis, clone UTERU3009979, highly  similar
           to Homo sapiens growth arrest-specific 6 (GAS6). ).
          Length = 624

 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 1/73 (1%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D++EC+   G C    C N  GSF C+C +G+ L+               + CG   C+N
Sbjct: 102 DVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKN 160

Query: 191 LPGSYVCLCPEGY 203
           LPGSY CLC EG+
Sbjct: 161 LPGSYSCLCDEGF 173



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 54/186 (29%), Positives = 65/186 (34%), Gaps = 27/186 (14%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAA 82
           CIN  GS        Y   S    C  +   +C      R GT+ C+D         M  
Sbjct: 41  CINKYGS-------PYTKNSGFATCVQNLPDQCTPNPCDRKGTQACQD--------LMGN 85

Query: 83  CCCSVGAAWGN-YCDPCPEPGSE---AYRQLCPGGPGY-----QPVLEPPSYVVTLADID 133
             C   A WG   CD      S+      Q+C   PG          E  S   T  DID
Sbjct: 86  FFCLCKAGWGGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDID 145

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPG 193
           ECA  E  C    C N  GS+ C C  G++ +             +   C   VC N PG
Sbjct: 146 ECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR-CEQ-VCVNSPG 202

Query: 194 SYVCLC 199
           SY C C
Sbjct: 203 SYTCHC 208



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD---SRKARCYGKV 59
           G  C D+DEC   ++C   +C N  GSY+C C   +   S   AC D     + RC    
Sbjct: 138 GRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRCEQVC 197

Query: 60  DLRSGTETC 68
               G+ TC
Sbjct: 198 VNSPGSYTC 206



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 31/111 (27%), Positives = 45/111 (40%), Gaps = 13/111 (11%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           DV+EC          C N  GS+ C C   +EL SDG  C D         +D  + +E 
Sbjct: 102 DVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQD---------IDECADSEA 152

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGNY---CDPCPEPGSEAYRQLCPGGPG 115
           C ++   +  G+  +C C  G A+ +    C    E       Q+C   PG
Sbjct: 153 CGEARCKNLPGSY-SCLCDEGFAYSSQEKACRDVDECLQGRCEQVCVNSPG 202



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 4/46 (8%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCP--PNYELVSDGTACYD 49
           C DVDEC   +  Q   C+N+ GSYTC C      +L  D   C D
Sbjct: 182 CRDVDECLQGRCEQV--CVNSPGSYTCHCDGRGGLKLSQDMDTCED 225



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 17/63 (26%), Positives = 25/63 (39%), Gaps = 3/63 (4%)

Query: 147 CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           C +  G+F C C AGW                + +     +C N PGS+ C C  G+   
Sbjct: 79  CQDLMGNFFCLCKAGWG---GRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELS 135

Query: 207 PNG 209
            +G
Sbjct: 136 SDG 138


>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
          Length = 2556

 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 61/211 (28%), Positives = 89/211 (42%), Gaps = 34/211 (16%)

Query: 3   GFNC-TDVDECKSPQSCQY-GQCINTQGSYTCRC-----PPNYELVSDGTACYDSRKARC 55
           G +C T+++EC S Q C+  G C +   +Y C C      PN E+  D  A        C
Sbjct: 597 GHHCETNINECSS-QPCRLRGTCQDPDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTC 655

Query: 56  YGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQLCPG 112
             K+D   G E C  + E    G+M  C  ++    GN C     C E G   +   CP 
Sbjct: 656 LDKID---GYE-C--ACEPGYTGSM--CNSNIDECAGNPCHNGGTC-EDGINGFTCRCP- 705

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
             GY    +P      L++++EC ++   C HG C ++   + C C  GWS         
Sbjct: 706 -EGYH---DP----TCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGWS--GTNCDIN 753

Query: 173 XXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                  P V G G C+++    VC C EG+
Sbjct: 754 NNECESNPCVNG-GTCKDMTSGIVCTCREGF 783



 Score = 59.7 bits (138), Expect = 8e-09
 Identities = 58/209 (27%), Positives = 76/209 (36%), Gaps = 23/209 (11%)

Query: 3   GFNCT-DVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           G  CT DVDEC+  P +CQ G  C NT G Y C C   +          D   A C+   
Sbjct: 289 GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGA 348

Query: 60  DLRSGTETCRDSDELSEDGTMAA---CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
                  +          G +      C S     G+ CD  P  G    + +C    GY
Sbjct: 349 TCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNG----KAICTCPSGY 404

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                 P+      D+DEC+     C H G C NT GSF C C  G++  P         
Sbjct: 405 TG----PA---CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT-GPRCEIDVNEC 456

Query: 176 XXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                + C     C +  G + C+C  GY
Sbjct: 457 VS---NPCQNDATCLDQIGEFQCMCMPGY 482



 Score = 57.2 bits (132), Expect = 4e-08
 Identities = 57/208 (27%), Positives = 80/208 (38%), Gaps = 29/208 (13%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  D+DEC  P  C YG C +   ++TC C P Y     G  C ++    C  +   
Sbjct: 560 GTHCEVDIDEC-DPDPCHYGSCKDGVATFTCLCRPGY----TGHHC-ETNINECSSQPCR 613

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQP 118
             G  TC+D D          C C  G    N     D C     ++   L     GY+ 
Sbjct: 614 LRG--TCQDPD------NAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCL-DKIDGYEC 664

Query: 119 VLEPPSYVVTL--ADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
             E P Y  ++  ++IDECA +   C + GTC +    F C C  G+             
Sbjct: 665 ACE-PGYTGSMCNSNIDECAGNP--CHNGGTCEDGINGFTCRCPEGY----HDPTCLSEV 717

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                + C  G CR+    Y C C  G+
Sbjct: 718 NECNSNPCVHGACRDSLNGYKCDCDPGW 745



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 55/204 (26%), Positives = 77/204 (37%), Gaps = 26/204 (12%)

Query: 8   DVDEC-KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           DV+EC + P+ C++G  C N  GSY C C   +     G  C +     C        GT
Sbjct: 178 DVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHT----GPNC-ERPYVPCSPSPCQNGGT 232

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQ-LCPGGPGYQPVLEP 122
             CR + +++ +     C C  G   G  C+   +  PG+       C  G        P
Sbjct: 233 --CRPTGDVTHE-----CACLPGFT-GQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCP 284

Query: 123 PSYV--VTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXR 179
           P +       D+DEC      C +G TC NT G + C C  GW+                
Sbjct: 285 PEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASA-- 342

Query: 180 PDVCGPG-VCRNLPGSYVCLCPEG 202
              C  G  C +   S+ C CP G
Sbjct: 343 --ACFHGATCHDRVASFYCECPHG 364



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 60/214 (28%), Positives = 77/214 (35%), Gaps = 29/214 (13%)

Query: 3    GFNC-TDVDECK-SPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
            G  C  D++EC  SP  C++G  C NT G Y C C   Y   +  T   D R   C+   
Sbjct: 864  GQTCEVDINECVLSP--CRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGG 921

Query: 60   DLRSGTETCRDSDELSEDGTMAA----CCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG-P 114
                G  T          GT        C S     G  C  C     ++Y   CP G  
Sbjct: 922  SCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDC----VDSYTCTCPAGFS 977

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
            G       P       D  E +   G    GTC +   SF C C  G++           
Sbjct: 978  GIHCENNTP-------DCTESSCFNG----GTCVDGINSFTCLCPPGFT--GSYCQHVVN 1024

Query: 175  XXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
                RP + G G C++  G + C CP+GY   PN
Sbjct: 1025 ECDSRPCLLG-GTCQDGRGLHRCTCPQGYTG-PN 1056



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 52/202 (25%), Positives = 77/202 (38%), Gaps = 28/202 (13%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           DV+EC S        C++  G + C C P YE    G  C +     C     L +G   
Sbjct: 452 DVNECVSNPCQNDATCLDQIGEFQCMCMPGYE----GVHC-EVNTDECASSPCLHNG--- 503

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQPVLEPP 123
            R  D+++E      C C  G   G+ C    D C     +   + C  GP     +   
Sbjct: 504 -RCLDKINE----FQCECPTGFT-GHLCQYDVDECASTPCKNGAK-CLDGPNTYTCVCTE 556

Query: 124 SYVVT--LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
            Y  T    DIDEC      C +G+C +   +F C C  G++               +P 
Sbjct: 557 GYTGTHCEVDIDECDPDP--CHYGSCKDGVATFTCLCRPGYT--GHHCETNINECSSQP- 611

Query: 182 VCG-PGVCRNLPGSYVCLCPEG 202
            C   G C++   +Y+C C +G
Sbjct: 612 -CRLRGTCQDPDNAYLCFCLKG 632



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 57/218 (26%), Positives = 76/218 (34%), Gaps = 26/218 (11%)

Query: 3    GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC + V  C S      G+C  T   Y C CP  +     G  C D     C      
Sbjct: 1054 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT----GLYC-DVPSVSCEVAAQ- 1107

Query: 62   RSGTET---CRDSDELSEDGTMAACCCSVGAAWGNYC----DPC-PEPGSEAYRQLCPGG 113
            R G +    C+      + G    C C  G   G+YC    D C P P           G
Sbjct: 1108 RQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT-GSYCEDLVDECSPSPCQNGATCTDYLG 1166

Query: 114  PGYQPVLEPPSYVVTLAD-IDECAAHEGLCAHG-TCTNTFGSFVCTC-----GAGWSLAP 166
             GY        + V  ++ IDEC +H   C +G TC +   ++ C+C     G    +  
Sbjct: 1167 -GYSCKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQGVHCEINV 1223

Query: 167  XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                         P     G C +  G Y C CP G+V
Sbjct: 1224 DDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1261



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 51/171 (29%), Positives = 66/171 (38%), Gaps = 31/171 (18%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  ++D+C S   C  G C++    Y C C P Y     G+ C +S    C G    
Sbjct: 635 GPNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGYT----GSMC-NSNIDECAGNPCH 688

Query: 62  RSGTETCRDSDELSEDGTMAACC-CSVGAAWGNYCDP-CPEPGSEAYRQLCPGGP----- 114
             GT  C       EDG     C C  G     Y DP C    +E     C  G      
Sbjct: 689 NGGT--C-------EDGINGFTCRCPEG-----YHDPTCLSEVNECNSNPCVHGACRDSL 734

Query: 115 -GYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWS 163
            GY+   +P  +  T  DI+        C +G TC +     VCTC  G+S
Sbjct: 735 NGYKCDCDP-GWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFS 784



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 61/218 (27%), Positives = 78/218 (35%), Gaps = 43/218 (19%)

Query: 3   GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC T+++EC S      G CI+    Y C C   Y     G  C +   A C      
Sbjct: 785 GPNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPY----TGATC-EVVLAPC-APSPC 838

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGS-----EAYR 107
           R+G E CR     SED    +C C    A G  C+         PC    S       YR
Sbjct: 839 RNGGE-CRQ----SEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYR 893

Query: 108 QLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAP 166
             C    GY       S      DID+C  +   C + G+CT+   +  C C  G+    
Sbjct: 894 CHCQA--GY-------SGRNCETDIDDCRPNP--CHNGGSCTDGINTAFCDCLPGF---- 938

Query: 167 XXXXXXXXXXXXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
                         D C  G  C +   SY C CP G+
Sbjct: 939 RGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGF 976



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 54/213 (25%), Positives = 80/213 (37%), Gaps = 30/213 (14%)

Query: 3    GFNC-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
            G NC TD+D+C+ P  C  G  C +   +  C C P +     GT C +     C     
Sbjct: 902  GRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDIN-EC----- 950

Query: 61   LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQ-LCPGGPG 115
                ++ CR+    ++      C C  G + G +C+     C E  S  +    C  G  
Sbjct: 951  ---ASDPCRNGANCTDCVDSYTCTCPAGFS-GIHCENNTPDCTE--SSCFNGGTCVDGIN 1004

Query: 116  YQPVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                L PP +  +     ++EC +   L   GTC +  G   CTC  G++  P       
Sbjct: 1005 SFTCLCPPGFTGSYCQHVVNECDSRPCLLG-GTCQDGRGLHRCTCPQGYT-GPNCQNLVH 1062

Query: 174  XXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
                  P   G G C      Y C CP G+  +
Sbjct: 1063 WCDSS-PCKNG-GKCWQTHTQYRCECPSGWTGL 1093



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/212 (24%), Positives = 74/212 (34%), Gaps = 29/212 (13%)

Query: 3    GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC++ +DEC S      G C++   +Y C CP      + G  C +     C   VD 
Sbjct: 1178 GVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRG----TQGVHC-EINVDDCNPPVDP 1232

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGSEAYRQL--- 109
             S +  C ++    +     +C C  G   G  C+         PC   G++   Q    
Sbjct: 1233 VSRSPKCFNNGTCVDQVGGYSCTCPPGFV-GERCEGDVNECLSNPCDARGTQNCVQRVND 1291

Query: 110  --CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPX 167
              C    G+         V+       C  + G CA    +NT   F+C C AG+  A  
Sbjct: 1292 FHCECRAGHTG--RRCESVINGCKGKPC-KNGGTCA--VASNTARGFICKCPAGFEGATC 1346

Query: 168  XXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
                              G C + P S  CLC
Sbjct: 1347 ENDARTCGSLR---CLNGGTCISGPRSPTCLC 1375



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 52/216 (24%), Positives = 77/216 (35%), Gaps = 30/216 (13%)

Query: 1   MPGF---NCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF   NC + +D+C        G C++   +Y C CPP +     G  C +     C 
Sbjct: 246 LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPEW----TGQYCTED-VDECQ 300

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGPG 115
              +      TC +    +  G    C C  G  W    + C E   +     C  G   
Sbjct: 301 LMPNACQNGGTCHN----THGG--YNCVCVNG--WTG--EDCSENIDDCASAACFHGATC 350

Query: 116 YQPVLE-----PPSYVVTLADIDECAAHEGLCAHGT-C-TNTF-GSFVCTCGAGWSLAPX 167
           +  V       P      L  +++ A     C  G+ C TN   G  +CTC +G++  P 
Sbjct: 351 HDRVASFYCECPHGRTGLLCHLND-ACISNPCNEGSNCDTNPVNGKAICTCPSGYT-GPA 408

Query: 168 XXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                             G C N  GS+ C C +GY
Sbjct: 409 CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY 444



 Score = 34.7 bits (76), Expect = 0.27
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 8/73 (10%)

Query: 133 DECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV-CRN 190
           DECA+    C H G C +    F C C  G++                P  C  G  C +
Sbjct: 492 DECASSP--CLHNGRCLDKINEFQCECPTGFT--GHLCQYDVDECASTP--CKNGAKCLD 545

Query: 191 LPGSYVCLCPEGY 203
            P +Y C+C EGY
Sbjct: 546 GPNTYTCVCTEGY 558


>U94333-1|AAB53110.1|  652|Homo sapiens C1qR(p) protein.
          Length = 652

 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 63/201 (31%), Positives = 76/201 (37%), Gaps = 36/201 (17%)

Query: 28  GSYTCRCPPNYELVSDGTACYDSR---KARCYGKVDLRSGTE----TCRDSDELSEDGTM 80
           GS+ C C P + L+ D   C        + C G      G      TCR       D + 
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340

Query: 81  AACCCSVGAAWGNYC-DPCPE-PGS---EAYRQLCPGGPGYQPVLEPPSYVVTLADIDEC 135
             C   V     + C   C   PG    E +    PGGPG               D+DEC
Sbjct: 341 LDCV-DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEG----------ACQDVDEC 389

Query: 136 AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GPG------VC 188
           A     CA G CTNT GSF C+C  G+ LA               D C GPG      +C
Sbjct: 390 ALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDV-----DECVGPGGPLCDSLC 443

Query: 189 RNLPGSYVCLCPEGYVAMPNG 209
            N  GS+ C C  G+V  PNG
Sbjct: 444 FNTQGSFHCGCLPGWVLAPNG 464



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 52/179 (29%), Positives = 63/179 (35%), Gaps = 19/179 (10%)

Query: 2   PGFNCTD-VDECKSPQSCQYGQC-------INTQG-SYTCRCPPNYELVSDGTACYD--- 49
           PGF   D +  C S   C    C       +   G +YTCRCP  Y+L S    C D   
Sbjct: 289 PGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDE 348

Query: 50  SRKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVG-AAWGNYCDPCPEPGSEAYRQ 108
            + + C  +     G   C         G     C  V   A G    PC +  +     
Sbjct: 349 CQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGR--SPCAQGCTNTDGS 406

Query: 109 L-CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
             C    GY    E  +      D+DEC    G      C NT GSF C C  GW LAP
Sbjct: 407 FHCSCEEGYVLAGEDGT---QCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAP 462



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G  C DVDEC  P    C    C NTQGS+ C C P + L  +G +C
Sbjct: 422 GTQCQDVDECVGPGGPLCD-SLCFNTQGSFHCGCLPGWVLAPNGVSC 467



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 19/71 (26%), Positives = 24/71 (33%), Gaps = 2/71 (2%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLP-- 192
           C  + G C         GSF+C C  G+ L                   G   C   P  
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323

Query: 193 GSYVCLCPEGY 203
            +Y C CP+GY
Sbjct: 324 KNYTCRCPQGY 334


>BC028075-1|AAH28075.1|  652|Homo sapiens CD93 molecule protein.
          Length = 652

 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 63/201 (31%), Positives = 76/201 (37%), Gaps = 36/201 (17%)

Query: 28  GSYTCRCPPNYELVSDGTACYDSR---KARCYGKVDLRSGTE----TCRDSDELSEDGTM 80
           GS+ C C P + L+ D   C        + C G      G      TCR       D + 
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340

Query: 81  AACCCSVGAAWGNYC-DPCPE-PGS---EAYRQLCPGGPGYQPVLEPPSYVVTLADIDEC 135
             C   V     + C   C   PG    E +    PGGPG               D+DEC
Sbjct: 341 LDCV-DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEG----------ACQDVDEC 389

Query: 136 AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GPG------VC 188
           A     CA G CTNT GSF C+C  G+ LA               D C GPG      +C
Sbjct: 390 ALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDV-----DECVGPGGPLCDSLC 443

Query: 189 RNLPGSYVCLCPEGYVAMPNG 209
            N  GS+ C C  G+V  PNG
Sbjct: 444 FNTQGSFHCGCLPGWVLAPNG 464



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 52/179 (29%), Positives = 63/179 (35%), Gaps = 19/179 (10%)

Query: 2   PGFNCTD-VDECKSPQSCQYGQC-------INTQG-SYTCRCPPNYELVSDGTACYD--- 49
           PGF   D +  C S   C    C       +   G +YTCRCP  Y+L S    C D   
Sbjct: 289 PGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDE 348

Query: 50  SRKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVG-AAWGNYCDPCPEPGSEAYRQ 108
            + + C  +     G   C         G     C  V   A G    PC +  +     
Sbjct: 349 CQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGR--SPCAQGCTNTDGS 406

Query: 109 L-CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
             C    GY    E  +      D+DEC    G      C NT GSF C C  GW LAP
Sbjct: 407 FHCSCEEGYVLAGEDGT---QCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAP 462



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G  C DVDEC  P    C    C NTQGS+ C C P + L  +G +C
Sbjct: 422 GTQCQDVDECVGPGGPLCD-SLCFNTQGSFHCGCLPGWVLAPNGVSC 467



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 19/71 (26%), Positives = 24/71 (33%), Gaps = 2/71 (2%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLP-- 192
           C  + G C         GSF+C C  G+ L                   G   C   P  
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323

Query: 193 GSYVCLCPEGY 203
            +Y C CP+GY
Sbjct: 324 KNYTCRCPQGY 334


>AL118508-1|CAC00597.1|  652|Homo sapiens complement component 1, q
           subcomponent, receptor 1 protein.
          Length = 652

 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 63/201 (31%), Positives = 76/201 (37%), Gaps = 36/201 (17%)

Query: 28  GSYTCRCPPNYELVSDGTACYDSR---KARCYGKVDLRSGTE----TCRDSDELSEDGTM 80
           GS+ C C P + L+ D   C        + C G      G      TCR       D + 
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340

Query: 81  AACCCSVGAAWGNYC-DPCPE-PGS---EAYRQLCPGGPGYQPVLEPPSYVVTLADIDEC 135
             C   V     + C   C   PG    E +    PGGPG               D+DEC
Sbjct: 341 LDCV-DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEG----------ACQDVDEC 389

Query: 136 AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GPG------VC 188
           A     CA G CTNT GSF C+C  G+ LA               D C GPG      +C
Sbjct: 390 ALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDV-----DECVGPGGPLCDSLC 443

Query: 189 RNLPGSYVCLCPEGYVAMPNG 209
            N  GS+ C C  G+V  PNG
Sbjct: 444 FNTQGSFHCGCLPGWVLAPNG 464



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 52/179 (29%), Positives = 63/179 (35%), Gaps = 19/179 (10%)

Query: 2   PGFNCTD-VDECKSPQSCQYGQC-------INTQG-SYTCRCPPNYELVSDGTACYD--- 49
           PGF   D +  C S   C    C       +   G +YTCRCP  Y+L S    C D   
Sbjct: 289 PGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDE 348

Query: 50  SRKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVG-AAWGNYCDPCPEPGSEAYRQ 108
            + + C  +     G   C         G     C  V   A G    PC +  +     
Sbjct: 349 CQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGR--SPCAQGCTNTDGS 406

Query: 109 L-CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
             C    GY    E  +      D+DEC    G      C NT GSF C C  GW LAP
Sbjct: 407 FHCSCEEGYVLAGEDGT---QCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAP 462



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G  C DVDEC  P    C    C NTQGS+ C C P + L  +G +C
Sbjct: 422 GTQCQDVDECVGPGGPLCD-SLCFNTQGSFHCGCLPGWVLAPNGVSC 467



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 19/71 (26%), Positives = 24/71 (33%), Gaps = 2/71 (2%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLP-- 192
           C  + G C         GSF+C C  G+ L                   G   C   P  
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323

Query: 193 GSYVCLCPEGY 203
            +Y C CP+GY
Sbjct: 324 KNYTCRCPQGY 334


>AK131552-1|BAD18686.1|  682|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16792 fis, clone TBAES2007379, moderately
           similar to Homo sapiens signal peptide, CUB domain,
           EGF-like 2 (SCUBE2). ).
          Length = 682

 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 53/187 (28%), Positives = 72/187 (38%), Gaps = 18/187 (9%)

Query: 18  CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDE-LSE 76
           CQ+  C +T     C C P Y++ +DG +C + R+       +  S T +  D D+ +  
Sbjct: 224 CQHS-CDDTADGPECSCHPQYKMHTDGRSCLE-REDTVLEVTE--SNTTSVVDGDKRVKR 279

Query: 77  DGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECA 136
              M  C  + G      CD   +  S      CP   G+   L+      T  DIDEC 
Sbjct: 280 QLLMETCAVNNGG-----CDRTCKDTSTGVHCSCP--VGFTLQLDGK----TCKDIDECQ 328

Query: 137 AHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYV 196
              G C H  C N  GSF C C  G+ L                  C    C N PG++ 
Sbjct: 329 TRNGGCDH-FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHS-CINHPGTFA 386

Query: 197 CLCPEGY 203
           C C  GY
Sbjct: 387 CACNRGY 393



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 131 DIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           DIDEC     G C H  C N  G++ CTC  G+ LA               +      C 
Sbjct: 86  DIDECGNELNGGCVHD-CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCV 144

Query: 190 NLPGSYVCLCPEGYVAMPN 208
           N+ GSY C C EG+    N
Sbjct: 145 NVMGSYECCCKEGFFLSDN 163



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D+DEC+  +  C H +C N  G+F C C  G++L                  C   VC N
Sbjct: 364 DVDECSL-DRTCDH-SCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQ-VCVN 420

Query: 191 LPGSYVCLCPEGY 203
             GSY C C  GY
Sbjct: 421 TVGSYECQCHPGY 433



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 11/88 (12%)

Query: 1   MPGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           + G  C D+DEC++        C N  GS+ C C   ++L++D  +C D         VD
Sbjct: 316 LDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQD---------VD 366

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVG 88
             S   TC D   ++  GT  AC C+ G
Sbjct: 367 ECSLDRTC-DHSCINHPGTF-ACACNRG 392



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 2/46 (4%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G NC DVDEC ++   CQ+  C+N  GSY C C   + L  +   C
Sbjct: 123 GHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLSDNQHTC 167



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 3/58 (5%)

Query: 3   GF-NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           GF +C D +EC  +   CQ   C+NT GSY C+C P Y+L  +   C  S    C  K
Sbjct: 397 GFTHCGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKLHWNKKDCVASCDLSCIVK 453



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 42/167 (25%), Positives = 64/167 (38%), Gaps = 19/167 (11%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARC 55
           G  C D+DEC +  +  C +  C+N  G+Y C C   + L  DG  C D          C
Sbjct: 81  GRQCEDIDECGNELNGGCVH-DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGC 139

Query: 56  -YGKVDLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR--QLCP 111
            +  V++    E  C++   LS++          G +  N    C     EA R    C 
Sbjct: 140 QHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACE 199

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTC 158
             PG++        ++T      C    G C H +C +T     C+C
Sbjct: 200 CRPGFELAKNQRDCILT------CNHGNGGCQH-SCDDTADGPECSC 239



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 131 DIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           D+DECA     C A   C NT  S+ C+C  G+                    C    C 
Sbjct: 45  DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHD-CL 103

Query: 190 NLPGSYVCLCPEGYVAMPNGSQYL 213
           N+PG+Y C C +G++   +G   L
Sbjct: 104 NIPGNYRCTCFDGFMLAHDGHNCL 127



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK 52
           +C DVDEC   ++C +  CIN  G++ C C   Y L    T C D+ +
Sbjct: 361 SCQDVDECSLDRTCDHS-CINHPGTFACACNRGYTLYG-FTHCGDTNE 406



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 4/44 (9%)

Query: 8  DVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYD 49
          DVDEC +    C     C NT  SY C C P Y+   +G  C D
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCED 86


>AB209895-1|BAD93132.1|  671|Homo sapiens complement component 1, q
           subcomponent, receptor 1 variant protein.
          Length = 671

 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 63/201 (31%), Positives = 76/201 (37%), Gaps = 36/201 (17%)

Query: 28  GSYTCRCPPNYELVSDGTACYDSR---KARCYGKVDLRSGTE----TCRDSDELSEDGTM 80
           GS+ C C P + L+ D   C        + C G      G      TCR       D + 
Sbjct: 300 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 359

Query: 81  AACCCSVGAAWGNYC-DPCPE-PGS---EAYRQLCPGGPGYQPVLEPPSYVVTLADIDEC 135
             C   V     + C   C   PG    E +    PGGPG               D+DEC
Sbjct: 360 LDCV-DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEG----------ACQDVDEC 408

Query: 136 AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-GPG------VC 188
           A     CA G CTNT GSF C+C  G+ LA               D C GPG      +C
Sbjct: 409 ALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDV-----DECVGPGGPLCDSLC 462

Query: 189 RNLPGSYVCLCPEGYVAMPNG 209
            N  GS+ C C  G+V  PNG
Sbjct: 463 FNTQGSFHCGCLPGWVLAPNG 483



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 52/179 (29%), Positives = 63/179 (35%), Gaps = 19/179 (10%)

Query: 2   PGFNCTD-VDECKSPQSCQYGQC-------INTQG-SYTCRCPPNYELVSDGTACYD--- 49
           PGF   D +  C S   C    C       +   G +YTCRCP  Y+L S    C D   
Sbjct: 308 PGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDE 367

Query: 50  SRKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVG-AAWGNYCDPCPEPGSEAYRQ 108
            + + C  +     G   C         G     C  V   A G    PC +  +     
Sbjct: 368 CQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGR--SPCAQGCTNTDGS 425

Query: 109 L-CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAP 166
             C    GY    E  +      D+DEC    G      C NT GSF C C  GW LAP
Sbjct: 426 FHCSCEEGYVLAGEDGT---QCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAP 481



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G  C DVDEC  P    C    C NTQGS+ C C P + L  +G +C
Sbjct: 441 GTQCQDVDECVGPGGPLCD-SLCFNTQGSFHCGCLPGWVLAPNGVSC 486



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 19/71 (26%), Positives = 24/71 (33%), Gaps = 2/71 (2%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLP-- 192
           C  + G C         GSF+C C  G+ L                   G   C   P  
Sbjct: 283 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 342

Query: 193 GSYVCLCPEGY 203
            +Y C CP+GY
Sbjct: 343 KNYTCRCPQGY 353


>BC111690-1|AAI11691.1|  807|Homo sapiens SCUBE2 protein protein.
          Length = 807

 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 52/186 (27%), Positives = 71/186 (38%), Gaps = 16/186 (8%)

Query: 18  CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSED 77
           CQ+  C +T     C C P Y++ +DG +C + R+       +  S T +  D D+  + 
Sbjct: 224 CQHS-CDDTADGPECSCHPQYKMHTDGRSCLE-REDTVLEVTE--SNTTSVVDGDKRVKR 279

Query: 78  GTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
             +   C    A     CD   +  S      CP   G+   L+      T  DIDEC  
Sbjct: 280 RLLMETC----AVNNGGCDRTCKDTSTGVHCSCP--VGFTLQLDGK----TCKDIDECQT 329

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVC 197
             G C H  C N  GSF C C  G+ L                  C    C N PG++ C
Sbjct: 330 RNGGCDH-FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHS-CINHPGTFAC 387

Query: 198 LCPEGY 203
            C  GY
Sbjct: 388 ACNRGY 393



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 131 DIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           DIDEC     G C H  C N  G++ CTC  G+ LA               +      C 
Sbjct: 86  DIDECGNELNGGCVHD-CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCV 144

Query: 190 NLPGSYVCLCPEGYVAMPN 208
           N+ GSY C C EG+    N
Sbjct: 145 NVMGSYECCCKEGFFLSDN 163



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 11/88 (12%)

Query: 1   MPGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           + G  C D+DEC++        C N  GS+ C C   ++L++D  +C D         VD
Sbjct: 316 LDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQD---------VD 366

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVG 88
             S   TC D   ++  GT  AC C+ G
Sbjct: 367 ECSLDRTC-DHSCINHPGTF-ACACNRG 392



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 2/46 (4%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G NC DVDEC ++   CQ+  C+N  GSY C C   + L  +   C
Sbjct: 123 GHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLSDNQHTC 167



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 3/58 (5%)

Query: 3   GF-NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           GF +C D +EC  +   CQ   C+NT GSY C+C P Y+L  +   C  S    C  K
Sbjct: 397 GFTHCGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKLHWNKKDCVASCDLSCIVK 453



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 42/167 (25%), Positives = 64/167 (38%), Gaps = 19/167 (11%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARC 55
           G  C D+DEC +  +  C +  C+N  G+Y C C   + L  DG  C D          C
Sbjct: 81  GRQCEDIDECGNELNGGCVH-DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGC 139

Query: 56  -YGKVDLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR--QLCP 111
            +  V++    E  C++   LS++          G +  N    C     EA R    C 
Sbjct: 140 QHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACE 199

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTC 158
             PG++        ++T      C    G C H +C +T     C+C
Sbjct: 200 CRPGFELAKNQRDCILT------CNHGNGGCQH-SCDDTADGPECSC 239



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 131 DIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           D+DECA     C A   C NT  S+ C+C  G+                    C    C 
Sbjct: 45  DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHD-CL 103

Query: 190 NLPGSYVCLCPEGYVAMPNGSQYL 213
           N+PG+Y C C +G++   +G   L
Sbjct: 104 NIPGNYRCTCFDGFMLAHDGHNCL 127



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK 52
           +C DVDEC   ++C +  CIN  G++ C C   Y L    T C D+ +
Sbjct: 361 SCQDVDECSLDRTCDHS-CINHPGTFACACNRGYTLYG-FTHCGDTNE 406



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 4/44 (9%)

Query: 8  DVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYD 49
          DVDEC +    C     C NT  SY C C P Y+   +G  C D
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCED 86


>AK123039-1|BAC85521.1|  971|Homo sapiens protein ( Homo sapiens
           cDNA FLJ41044 fis, clone NT2RP7000466, highly  similar
           to Mus musculus CUB domain and EGF-like repeat
           containing 1 (Cegf1). ).
          Length = 971

 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 52/186 (27%), Positives = 71/186 (38%), Gaps = 16/186 (8%)

Query: 18  CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSED 77
           CQ+  C +T     C C P Y++ +DG +C + R+       +  S T +  D D+  + 
Sbjct: 224 CQHS-CDDTADGPECSCHPQYKMHTDGRSCLE-REDTVLEVTE--SNTTSVVDGDKRVKR 279

Query: 78  GTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
             +   C    A     CD   +  S      CP   G+   L+      T  DIDEC  
Sbjct: 280 RLLMETC----AVNNGGCDRTCKDTSTGVHCSCP--VGFTLQLDGK----TCKDIDECQT 329

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVC 197
             G C H  C N  GSF C C  G+ L                  C    C N PG++ C
Sbjct: 330 RNGGCDH-FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHS-CINHPGTFAC 387

Query: 198 LCPEGY 203
            C  GY
Sbjct: 388 ACNRGY 393



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 131 DIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           DIDEC     G C H  C N  G++ CTC  G+ LA               +      C 
Sbjct: 86  DIDECGNELNGGCVHD-CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCV 144

Query: 190 NLPGSYVCLCPEGYVAMPN 208
           N+ GSY C C EG+    N
Sbjct: 145 NVMGSYECCCKEGFFLSDN 163



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 11/88 (12%)

Query: 1   MPGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           + G  C D+DEC++        C N  GS+ C C   ++L++D  +C D         VD
Sbjct: 316 LDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQD---------VD 366

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVG 88
             S   TC D   ++  GT  AC C+ G
Sbjct: 367 ECSLDRTC-DHSCINHPGTF-ACACNRG 392



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 2/46 (4%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G NC DVDEC ++   CQ+  C+N  GSY C C   + L  +   C
Sbjct: 123 GHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLSDNQHTC 167



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 42/167 (25%), Positives = 64/167 (38%), Gaps = 19/167 (11%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARC 55
           G  C D+DEC +  +  C +  C+N  G+Y C C   + L  DG  C D          C
Sbjct: 81  GRQCEDIDECGNELNGGCVH-DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGC 139

Query: 56  -YGKVDLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR--QLCP 111
            +  V++    E  C++   LS++          G +  N    C     EA R    C 
Sbjct: 140 QHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACE 199

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTC 158
             PG++        ++T      C    G C H +C +T     C+C
Sbjct: 200 CRPGFELAKNQRDCILT------CNHGNGGCQH-SCDDTADGPECSC 239



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 131 DIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           D+DECA     C A   C NT  S+ C+C  G+                    C    C 
Sbjct: 45  DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHD-CL 103

Query: 190 NLPGSYVCLCPEGYVAMPNGSQYL 213
           N+PG+Y C C +G++   +G   L
Sbjct: 104 NIPGNYRCTCFDGFMLAHDGHNCL 127



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK 52
           +C DVDEC   ++C +  CIN  G++ C C   Y L    T C D+ +
Sbjct: 361 SCQDVDECSLDRTCDHS-CINHPGTFACACNRGYTLYG-FTHCGDTNE 406



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 3/40 (7%)

Query: 3   GF-NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYEL 40
           GF +C D +EC  +   CQ   C+NT GSY C+C P Y+L
Sbjct: 397 GFTHCGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKL 435



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 4/44 (9%)

Query: 8  DVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYD 49
          DVDEC +    C     C NT  SY C C P Y+   +G  C D
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCED 86


>AJ400877-1|CAB92285.1|  999|Homo sapiens CEGP1 protein protein.
          Length = 999

 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 52/186 (27%), Positives = 71/186 (38%), Gaps = 16/186 (8%)

Query: 18  CQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSED 77
           CQ+  C +T     C C P Y++ +DG +C + R+       +  S T +  D D+  + 
Sbjct: 224 CQHS-CDDTADGPECSCHPQYKMHTDGRSCLE-REDTVLEVTE--SNTTSVVDGDKRVKR 279

Query: 78  GTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
             +   C    A     CD   +  S      CP   G+   L+      T  DIDEC  
Sbjct: 280 RLLMETC----AVNNGGCDRTCKDTSTGVHCSCP--VGFTLQLDGK----TCKDIDECQT 329

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVC 197
             G C H  C N  GSF C C  G+ L                  C    C N PG++ C
Sbjct: 330 RNGGCDH-FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHS-CINHPGTFAC 387

Query: 198 LCPEGY 203
            C  GY
Sbjct: 388 ACNRGY 393



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 131 DIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           DIDEC     G C H  C N  G++ CTC  G+ LA               +      C 
Sbjct: 86  DIDECGNELNGGCVHD-CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCV 144

Query: 190 NLPGSYVCLCPEGYVAMPN 208
           N+ GSY C C EG+    N
Sbjct: 145 NVMGSYECCCKEGFFLSDN 163



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 11/88 (12%)

Query: 1   MPGFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           + G  C D+DEC++        C N  GS+ C C   ++L++D  +C D         VD
Sbjct: 316 LDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQD---------VD 366

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVG 88
             S   TC D   ++  GT  AC C+ G
Sbjct: 367 ECSLDRTC-DHSCINHPGTF-ACACNRG 392



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 2/46 (4%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G NC DVDEC ++   CQ+  C+N  GSY C C   + L  +   C
Sbjct: 123 GHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLSDNQHTC 167



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 42/167 (25%), Positives = 64/167 (38%), Gaps = 19/167 (11%)

Query: 3   GFNCTDVDECKSPQS--CQYGQCINTQGSYTCRCPPNYELVSDGTACYD-----SRKARC 55
           G  C D+DEC +  +  C +  C+N  G+Y C C   + L  DG  C D          C
Sbjct: 81  GRQCEDIDECGNELNGGCVH-DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGC 139

Query: 56  -YGKVDLRSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR--QLCP 111
            +  V++    E  C++   LS++          G +  N    C     EA R    C 
Sbjct: 140 QHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACE 199

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTC 158
             PG++        ++T      C    G C H +C +T     C+C
Sbjct: 200 CRPGFELAKNQRDCILT------CNHGNGGCQH-SCDDTADGPECSC 239



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 131 DIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCR 189
           D+DECA     C A   C NT  S+ C+C  G+                    C    C 
Sbjct: 45  DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHD-CL 103

Query: 190 NLPGSYVCLCPEGYVAMPNGSQYL 213
           N+PG+Y C C +G++   +G   L
Sbjct: 104 NIPGNYRCTCFDGFMLAHDGHNCL 127



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK 52
           +C DVDEC   ++C +  CIN  G++ C C   Y L    T C D+ +
Sbjct: 361 SCQDVDECSLDRTCDHS-CINHPGTFACACNRGYTLYG-FTHCGDTNE 406



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 3/40 (7%)

Query: 3   GF-NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYEL 40
           GF +C D +EC  +   CQ   C+NT GSY C+C P Y+L
Sbjct: 397 GFTHCGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKL 435



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 4/44 (9%)

Query: 8  DVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYD 49
          DVDEC +    C     C NT  SY C C P Y+   +G  C D
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCED 86


>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
          Length = 2003

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 61/208 (29%), Positives = 85/208 (40%), Gaps = 32/208 (15%)

Query: 8   DVDEC----KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           D+DEC    + P  C++G  C+NT GS+ C CPP Y     G+ C ++    C  +    
Sbjct: 432 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRC-EADHNECLSQ-PCH 485

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPGYQP 118
            G+ TC D            C C  G   G  C+     C       +        G+Q 
Sbjct: 486 PGS-TCLDLLATFH------CLCPPGLE-GQLCEVETNECASAPCLNHADCHDLLNGFQC 537

Query: 119 VLEPP-SYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
           +  P  S      DIDEC +    CA+G  C +  G+F C C  G+   P          
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFE-GPRCQTEVDECL 594

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
               D C  G  C +LPG++ CLCP G+
Sbjct: 595 S---DPCPVGASCLDLPGAFFCLCPSGF 619



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 55/215 (25%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 1   MPGFN---CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDS---- 50
           MPG+    C   D C +      G C+ T     C CPP +E      D   C+      
Sbjct: 146 MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205

Query: 51  -RKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
            +   C+    L S    C    E       A  C   G + G  C   PE  S  +  L
Sbjct: 206 PKGTSCHN--TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 263

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXX 168
           CP  PG+   + P   V    + D C +H+  C + GTC +   ++ C C   W+     
Sbjct: 264 CP--PGF---IGPDCEV----NPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGWDCS 312

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      P     G C+N  GS+ C+C  G+
Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW 347



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 27/212 (12%)

Query: 3   GFNCT-DVDECKS--PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-G 57
           G++C+ DVDEC++  P  C+ G  C N+ GS+ C C   +   S      D   A C  G
Sbjct: 308 GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG 367

Query: 58  KVDL-RSGTETCR-DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG 115
              + R G+ +C            +   C S        C   P  GS     LC   PG
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST----LCLCQPG 423

Query: 116 YQPVLEPPSYVVTLADIDECA-AHEGL--CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
           Y     P  +     D+DEC  A +G   C HG +C NT GSF C C  G++        
Sbjct: 424 YSG---PTCH----QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--GSRCEA 474

Query: 172 XXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                  +P  C PG  C +L  ++ CLCP G
Sbjct: 475 DHNECLSQP--CHPGSTCLDLLATFHCLCPPG 504



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 54/208 (25%), Positives = 72/208 (34%), Gaps = 31/208 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF+ T    D+DEC+S      GQC +  G++ C+C P +E              RC 
Sbjct: 540 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE------------GPRCQ 587

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGGPG 115
            +VD    ++ C       +      C C  G   G  C+ P   P     +Q+C     
Sbjct: 588 TEVD-ECLSDPCPVGASCLDLPGAFFCLCPSGFT-GQLCEVPLCAPNLCQPKQICKDQKD 645

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               L P          D C  H G C   +         C C  GW+  P         
Sbjct: 646 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---------CVCDVGWT-GPECEAELGGC 695

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C   P  Y C CP GY
Sbjct: 696 ISA-PCAHG-GTCYPQPSGYNCTCPTGY 721



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 63/218 (28%), Positives = 82/218 (37%), Gaps = 32/218 (14%)

Query: 2   PGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCY 56
           PGF   +C  + D C S Q    G C +   +YTC CP  +     G  C  D  +    
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQ 321

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGP- 114
           G    R+G  TC++S      G+    C S    WG     C E   +     C PG   
Sbjct: 322 GPPHCRNGG-TCQNSA-----GSFHCVCVS---GWGG--TSCEENLDDCIAATCAPGSTC 370

Query: 115 ----GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
               G    L PP     L  +++    +       C TN   GS +C C  G+S  P  
Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS-GPTC 429

Query: 169 XXXXXXXXXXR--PDVCGPG-VCRNLPGSYVCLCPEGY 203
                     +  P  C  G  C N PGS+ CLCP GY
Sbjct: 430 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 46/210 (21%), Positives = 69/210 (32%), Gaps = 28/210 (13%)

Query: 7   TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           T  D C S      G C+N  G+++C C   ++              RC GK+       
Sbjct: 766 TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQ------------GPRCEGKLRPSCADS 813

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQPVL--- 120
            CR+     +      C C  G   G+     D C +            GP +  +    
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQG 873

Query: 121 -EPPSYVVTLADIDECAAHEG-----LCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P   + L+   + A  +G     LC + G C ++  S+ C C  G+           
Sbjct: 874 WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHV 931

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                RP   G   C   P  Y+C C  GY
Sbjct: 932 NPCESRPCQNG-ATCMAQPSGYLCQCAPGY 960



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 131 DIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VC 188
           D++EC    G C  GT C NT GSF C C  G    P             P  C  G  C
Sbjct: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GPRCELRAGPCP---PRGCSNGGTC 249

Query: 189 RNLPGS----YVCLCPEGYV 204
           + +P      ++CLCP G++
Sbjct: 250 QLMPEKDSTFHLCLCPPGFI 269



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 52/214 (24%), Positives = 75/214 (35%), Gaps = 27/214 (12%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C++ +  C S      G C  + G Y C CPP++     G  C  S    C      
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTD-YCVSAPCF 777

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE----AYRQLCPGGPGYQ 117
             G  TC     ++  GT  +C C++G   G  C+    P         R  C   P   
Sbjct: 778 NGG--TC-----VNRPGTF-SCLCAMGFQ-GPRCEGKLRPSCADSPCRNRATCQDSPQGP 828

Query: 118 PVLEPPSYV-VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXX 174
             L P  Y   +   + +  A +    +  C  T  SF C C  GW+  L          
Sbjct: 829 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQK 888

Query: 175 XXXXR----PDVC-GPGVCRNLPGSYVCLCPEGY 203
               +      +C   G+C +   SY C CP G+
Sbjct: 889 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/172 (29%), Positives = 64/172 (37%), Gaps = 23/172 (13%)

Query: 2    PGFN---CTD-VDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            PGF    C D V+ C+S + CQ G  C+     Y C+C P Y    DG  C     A C 
Sbjct: 920  PGFQGSLCQDHVNPCES-RPCQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDA-CQ 973

Query: 57   GKVDLRSGTETCRDSDE--LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
             +     GT T +          G +   C   G        PC   G+ A   L     
Sbjct: 974  SQPCHNHGTCTPKPGGFHCACPPGFVGLRC--EGDVDECLDQPCHPTGTAACHSL--ANA 1029

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGS---FVCTCGAGW 162
             Y   L   +      +ID C  H   C H GTC  T GS   F+C C  G+
Sbjct: 1030 FYCQCLPGHTGQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGF 1079



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 51/212 (24%), Positives = 69/212 (32%), Gaps = 28/212 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQ--GSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C   D C S       QC      GS  C C P Y     G  C+      C   + 
Sbjct: 387 GLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLD-EC---LM 438

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
            + G   C              C C  G   G+ C+      +E   Q C  G     +L
Sbjct: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYT-GSRCEA---DHNECLSQPCHPGSTCLDLL 494

Query: 121 E------PPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  PP     L +++  ECA+   L  H  C +    F C C  G+S         
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFS----GTRCE 549

Query: 173 XXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                 R   C   G C++ PG++ C C  G+
Sbjct: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGF 581



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 46/191 (24%), Positives = 69/191 (36%), Gaps = 24/191 (12%)

Query: 21   GQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTM 80
            G C+++  SY C CPP ++    G+ C D     C  +   ++G  TC         G +
Sbjct: 905  GLCVDSGPSYFCHCPPGFQ----GSLCQDHVNP-CESR-PCQNGA-TCM----AQPSGYL 953

Query: 81   AACCCSV-GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLA--DIDECAA 137
              C     G       D C       +    P   G+     PP +V      D+DEC  
Sbjct: 954  CQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDECL- 1011

Query: 138  HEGLCAHGT--CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS- 194
             +     GT  C +   +F C C  G +               +P   G G C    GS 
Sbjct: 1012 DQPCHPTGTAACHSLANAFYCQCLPGHT--GQWCEVEIDPCHSQPCFHG-GTCEATAGSP 1068

Query: 195  --YVCLCPEGY 203
              ++C CP+G+
Sbjct: 1069 LGFICHCPKGF 1079



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 20/87 (22%), Positives = 30/87 (34%), Gaps = 6/87 (6%)

Query: 122  PPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
            PP +  +L            C +G TC      ++C C  G+                + 
Sbjct: 919  PPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD----GQNCSKELDACQS 974

Query: 181  DVC-GPGVCRNLPGSYVCLCPEGYVAM 206
              C   G C   PG + C CP G+V +
Sbjct: 975  QPCHNHGTCTPKPGGFHCACPPGFVGL 1001


>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
          Length = 1999

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 61/208 (29%), Positives = 85/208 (40%), Gaps = 32/208 (15%)

Query: 8   DVDEC----KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           D+DEC    + P  C++G  C+NT GS+ C CPP Y     G+ C ++    C  +    
Sbjct: 431 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRC-EADHNECLSQ-PCH 484

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPGYQP 118
            G+ TC D            C C  G   G  C+     C       +        G+Q 
Sbjct: 485 PGS-TCLDLLATFH------CLCPPGLE-GQLCEVETNECASAPCLNHADCHDLLNGFQC 536

Query: 119 VLEPP-SYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
           +  P  S      DIDEC +    CA+G  C +  G+F C C  G+   P          
Sbjct: 537 ICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFE-GPRCQTEVDECL 593

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
               D C  G  C +LPG++ CLCP G+
Sbjct: 594 S---DPCPVGASCLDLPGAFFCLCPSGF 618



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 55/215 (25%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 1   MPGFN---CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDS---- 50
           MPG+    C   D C +      G C+ T     C CPP +E      D   C+      
Sbjct: 145 MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 204

Query: 51  -RKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
            +   C+    L S    C    E       A  C   G + G  C   PE  S  +  L
Sbjct: 205 PKGTSCHN--TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 262

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXX 168
           CP  PG+   + P   V    + D C +H+  C + GTC +   ++ C C   W+     
Sbjct: 263 CP--PGF---IGPGCEV----NPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGWDCS 311

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      P     G C+N  GS+ C+C  G+
Sbjct: 312 EDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGW 346



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 27/212 (12%)

Query: 3   GFNCT-DVDECKS--PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-G 57
           G++C+ DVDEC++  P  C+ G  C N+ GS+ C C   +   S      D   A C  G
Sbjct: 307 GWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG 366

Query: 58  KVDL-RSGTETCR-DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG 115
              + R G+ +C            +   C S        C   P  GS     LC   PG
Sbjct: 367 STCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST----LCLCQPG 422

Query: 116 YQPVLEPPSYVVTLADIDECA-AHEGL--CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
           Y     P  +     D+DEC  A +G   C HG +C NT GSF C C  G++        
Sbjct: 423 YSG---PTCH----QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--GSRCEA 473

Query: 172 XXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                  +P  C PG  C +L  ++ CLCP G
Sbjct: 474 DHNECLSQP--CHPGSTCLDLLATFHCLCPPG 503



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 54/208 (25%), Positives = 72/208 (34%), Gaps = 31/208 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF+ T    D+DEC+S      GQC +  G++ C+C P +E              RC 
Sbjct: 539 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE------------GPRCQ 586

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGGPG 115
            +VD    ++ C       +      C C  G   G  C+ P   P     +Q+C     
Sbjct: 587 TEVD-ECLSDPCPVGASCLDLPGAFFCLCPSGFT-GQLCEVPLCAPNLCQPKQICKDQKD 644

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               L P          D C  H G C   +         C C  GW+  P         
Sbjct: 645 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---------CVCDVGWT-GPECEAELGGC 694

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C   P  Y C CP GY
Sbjct: 695 ISA-PCAHG-GTCYPQPSGYNCTCPTGY 720



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 63/218 (28%), Positives = 81/218 (37%), Gaps = 32/218 (14%)

Query: 2   PGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCY 56
           PGF    C  + D C S Q    G C +   +YTC CP  +     G  C  D  +    
Sbjct: 265 PGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECEAQ 320

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGP- 114
           G    R+G  TC++S      G+    C S    WG     C E   +     C PG   
Sbjct: 321 GPPHCRNGG-TCQNSA-----GSFHCVCVS---GWGG--TSCEENLDDCIAATCAPGSTC 369

Query: 115 ----GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
               G    L PP     L  +++    +       C TN   GS +C C  G+S  P  
Sbjct: 370 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS-GPTC 428

Query: 169 XXXXXXXXXXR--PDVCGPG-VCRNLPGSYVCLCPEGY 203
                     +  P  C  G  C N PGS+ CLCP GY
Sbjct: 429 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 466



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 46/210 (21%), Positives = 69/210 (32%), Gaps = 28/210 (13%)

Query: 7   TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           T  D C S      G C+N  G+++C C   ++              RC GK+       
Sbjct: 765 TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQ------------GPRCEGKLRPSCADS 812

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQPVL--- 120
            CR+     +      C C  G   G+     D C +            GP +  +    
Sbjct: 813 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQG 872

Query: 121 -EPPSYVVTLADIDECAAHEG-----LCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P   + L+   + A  +G     LC + G C ++  S+ C C  G+           
Sbjct: 873 WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHV 930

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                RP   G   C   P  Y+C C  GY
Sbjct: 931 NPCESRPCQNG-ATCMAQPSGYLCQCAPGY 959



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 131 DIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VC 188
           D++EC    G C  GT C NT GSF C C  G    P             P  C  G  C
Sbjct: 193 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GPRCELRAGPCP---PRGCSNGGTC 248

Query: 189 RNLPGS----YVCLCPEGYV 204
           + +P      ++CLCP G++
Sbjct: 249 QLMPEKDSTFHLCLCPPGFI 268



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 52/214 (24%), Positives = 75/214 (35%), Gaps = 27/214 (12%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C++ +  C S      G C  + G Y C CPP++     G  C  S    C      
Sbjct: 722 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTD-YCVSAPCF 776

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE----AYRQLCPGGPGYQ 117
             G  TC     ++  GT  +C C++G   G  C+    P         R  C   P   
Sbjct: 777 NGG--TC-----VNRPGTF-SCLCAMGFQ-GPRCEGKLRPSCADSPCRNRATCQDSPQGP 827

Query: 118 PVLEPPSYV-VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXX 174
             L P  Y   +   + +  A +    +  C  T  SF C C  GW+  L          
Sbjct: 828 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQK 887

Query: 175 XXXXR----PDVC-GPGVCRNLPGSYVCLCPEGY 203
               +      +C   G+C +   SY C CP G+
Sbjct: 888 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 921



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/172 (29%), Positives = 64/172 (37%), Gaps = 23/172 (13%)

Query: 2    PGFN---CTD-VDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            PGF    C D V+ C+S + CQ G  C+     Y C+C P Y    DG  C     A C 
Sbjct: 919  PGFQGSLCQDHVNPCES-RPCQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDA-CQ 972

Query: 57   GKVDLRSGTETCRDSDE--LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
             +     GT T +          G +   C   G        PC   G+ A   L     
Sbjct: 973  SQPCHNHGTCTPKPGGFHCACPPGFVGLRC--EGDVDECLDQPCHPTGTAACHSL--ANA 1028

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGS---FVCTCGAGW 162
             Y   L   +      +ID C  H   C H GTC  T GS   F+C C  G+
Sbjct: 1029 FYCQCLPGHTGQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGF 1078



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 51/212 (24%), Positives = 69/212 (32%), Gaps = 28/212 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQ--GSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C   D C S       QC      GS  C C P Y     G  C+      C   + 
Sbjct: 386 GLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLD-EC---LM 437

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
            + G   C              C C  G   G+ C+      +E   Q C  G     +L
Sbjct: 438 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYT-GSRCEA---DHNECLSQPCHPGSTCLDLL 493

Query: 121 E------PPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  PP     L +++  ECA+   L  H  C +    F C C  G+S         
Sbjct: 494 ATFHCLCPPGLEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFS----GTRCE 548

Query: 173 XXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                 R   C   G C++ PG++ C C  G+
Sbjct: 549 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGF 580



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 46/191 (24%), Positives = 69/191 (36%), Gaps = 24/191 (12%)

Query: 21   GQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTM 80
            G C+++  SY C CPP ++    G+ C D     C  +   ++G  TC         G +
Sbjct: 904  GLCVDSGPSYFCHCPPGFQ----GSLCQDHVNP-CESR-PCQNGA-TCM----AQPSGYL 952

Query: 81   AACCCSV-GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLA--DIDECAA 137
              C     G       D C       +    P   G+     PP +V      D+DEC  
Sbjct: 953  CQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDECL- 1010

Query: 138  HEGLCAHGT--CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS- 194
             +     GT  C +   +F C C  G +               +P   G G C    GS 
Sbjct: 1011 DQPCHPTGTAACHSLANAFYCQCLPGHT--GQWCEVEIDPCHSQPCFHG-GTCEATAGSP 1067

Query: 195  --YVCLCPEGY 203
              ++C CP+G+
Sbjct: 1068 LGFICHCPKGF 1078



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 20/87 (22%), Positives = 30/87 (34%), Gaps = 6/87 (6%)

Query: 122  PPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
            PP +  +L            C +G TC      ++C C  G+                + 
Sbjct: 918  PPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD----GQNCSKELDACQS 973

Query: 181  DVC-GPGVCRNLPGSYVCLCPEGYVAM 206
              C   G C   PG + C CP G+V +
Sbjct: 974  QPCHNHGTCTPKPGGFHCACPPGFVGL 1000


>M16552-1|AAB59508.1|  575|Homo sapiens THBD protein.
          Length = 575

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 56/169 (33%), Positives = 79/169 (46%), Gaps = 27/169 (15%)

Query: 6   CTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR----KARC-YGKV 59
           C DVD+C   P  C   +C+NTQG + C C PNY+LV DG  C +      +A C Y   
Sbjct: 323 CEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLV-DGE-CVEPVDPCFRANCEYQCQ 379

Query: 60  DLRSGTETCRDSD---ELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            L   +  C  ++    +  +       C+  A   + CDP  +   E     CP   GY
Sbjct: 380 PLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-CDPNTQASCE-----CP--EGY 431

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
             +L+   ++ T  DIDEC  + G C+ G C N  G+F C CG   +LA
Sbjct: 432 --ILDD-GFICT--DIDECE-NGGFCS-GVCHNLPGTFECICGPDSALA 473



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/51 (45%), Positives = 29/51 (56%), Gaps = 3/51 (5%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSD-GTACYDSRK 52
           GF CTD+DEC++   C  G C N  G++ C C P+  L    GT C DS K
Sbjct: 436 GFICTDIDECENGGFCS-GVCHNLPGTFECICGPDSALARHIGTDC-DSGK 484



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 3/72 (4%)

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN--L 191
           +C+   G C H  C    G+  C C AG +L                D+C      N   
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302

Query: 192 PGSYVCLCPEGY 203
           PGSY C+C  GY
Sbjct: 303 PGSYSCMCETGY 314



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 50/191 (26%), Positives = 73/191 (38%), Gaps = 24/191 (12%)

Query: 28  GSYTCRCPPNYELVSDGTACYDS-----RKARCYGK-VDLRSGTET-CRDSDELSEDGTM 80
           GSY+C C   Y L +D   C D        + C  + V+ + G E  C  + +L  DG  
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGE- 361

Query: 81  AACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
             C   V   +   C+   +P ++    LC    G+ P+   P       +   C A   
Sbjct: 362 --CVEPVDPCFRANCEYQCQPLNQT-SYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-- 416

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC- 199
            C      NT  S  C C  G+ L                  C  GVC NLPG++ C+C 
Sbjct: 417 -CD----PNTQAS--CECPEGYIL-DDGFICTDIDECENGGFCS-GVCHNLPGTFECICG 467

Query: 200 PEGYVAMPNGS 210
           P+  +A   G+
Sbjct: 468 PDSALARHIGT 478



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 35/139 (25%), Positives = 43/139 (30%), Gaps = 15/139 (10%)

Query: 78  GTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADI 132
           G    C    GA  G++    P        +      C   PG  P  + P+     AD 
Sbjct: 219 GLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPG-APRCQCPAGAALQADG 277

Query: 133 DECAAH-----EGLCAHGTCTNTF--GSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCG 184
             C A        LC H    N    GS+ C C  G+ LA               P  C 
Sbjct: 278 RSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC- 336

Query: 185 PGVCRNLPGSYVCLCPEGY 203
           P  C N  G + C C   Y
Sbjct: 337 PQRCVNTQGGFECHCYPNY 355


>J02973-1|AAA61175.1|  575|Homo sapiens THBD protein.
          Length = 575

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 56/169 (33%), Positives = 79/169 (46%), Gaps = 27/169 (15%)

Query: 6   CTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR----KARC-YGKV 59
           C DVD+C   P  C   +C+NTQG + C C PNY+LV DG  C +      +A C Y   
Sbjct: 323 CEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLV-DGE-CVEPVDPCFRANCEYQCQ 379

Query: 60  DLRSGTETCRDSD---ELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            L   +  C  ++    +  +       C+  A   + CDP  +   E     CP   GY
Sbjct: 380 PLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-CDPNTQASCE-----CP--EGY 431

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
             +L+   ++ T  DIDEC  + G C+ G C N  G+F C CG   +LA
Sbjct: 432 --ILDD-GFICT--DIDECE-NGGFCS-GVCHNLPGTFECICGPDSALA 473



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/51 (45%), Positives = 29/51 (56%), Gaps = 3/51 (5%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSD-GTACYDSRK 52
           GF CTD+DEC++   C  G C N  G++ C C P+  L    GT C DS K
Sbjct: 436 GFICTDIDECENGGFCS-GVCHNLPGTFECICGPDSALARHIGTDC-DSGK 484



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 3/72 (4%)

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN--L 191
           +C+   G C H  C    G+  C C AG +L                D+C      N   
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302

Query: 192 PGSYVCLCPEGY 203
           PGSY C+C  GY
Sbjct: 303 PGSYSCMCETGY 314



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 50/191 (26%), Positives = 73/191 (38%), Gaps = 24/191 (12%)

Query: 28  GSYTCRCPPNYELVSDGTACYDS-----RKARCYGK-VDLRSGTET-CRDSDELSEDGTM 80
           GSY+C C   Y L +D   C D        + C  + V+ + G E  C  + +L  DG  
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGE- 361

Query: 81  AACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
             C   V   +   C+   +P ++    LC    G+ P+   P       +   C A   
Sbjct: 362 --CVEPVDPCFRANCEYQCQPLNQT-SYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-- 416

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC- 199
            C      NT  S  C C  G+ L                  C  GVC NLPG++ C+C 
Sbjct: 417 -CD----PNTQAS--CECPEGYIL-DDGFICTDIDECENGGFCS-GVCHNLPGTFECICG 467

Query: 200 PEGYVAMPNGS 210
           P+  +A   G+
Sbjct: 468 PDSALARHIGT 478



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 35/139 (25%), Positives = 43/139 (30%), Gaps = 15/139 (10%)

Query: 78  GTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADI 132
           G    C    GA  G++    P        +      C   PG  P  + P+     AD 
Sbjct: 219 GLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPG-APRCQCPAGAALQADG 277

Query: 133 DECAAH-----EGLCAHGTCTNTF--GSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCG 184
             C A        LC H    N    GS+ C C  G+ LA               P  C 
Sbjct: 278 RSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC- 336

Query: 185 PGVCRNLPGSYVCLCPEGY 203
           P  C N  G + C C   Y
Sbjct: 337 PQRCVNTQGGFECHCYPNY 355


>D86566-1|BAA13116.1|  955|Homo sapiens notch related protein
           protein.
          Length = 955

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 61/208 (29%), Positives = 85/208 (40%), Gaps = 32/208 (15%)

Query: 8   DVDEC----KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           D+DEC    + P  C++G  C+NT GS+ C CPP Y     G+ C ++    C  +    
Sbjct: 432 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRC-EADHNECLSQ-PCH 485

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPGYQP 118
            G+ TC D            C C  G   G  C+     C       +        G+Q 
Sbjct: 486 PGS-TCLDLLATFH------CLCPPGLE-GQLCEVETNECASAPCLNHADCHDLLNGFQC 537

Query: 119 VLEPP-SYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
           +  P  S      DIDEC +    CA+G  C +  G+F C C  G+   P          
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFE-GPRCQTEVDECL 594

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
               D C  G  C +LPG++ CLCP G+
Sbjct: 595 S---DPCPVGASCLDLPGAFFCLCPSGF 619



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 55/215 (25%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 1   MPGFN---CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDS---- 50
           MPG+    C   D C +      G C+ T     C CPP +E      D   C+      
Sbjct: 146 MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205

Query: 51  -RKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
            +   C+    L S    C    E       A  C   G + G  C   PE  S  +  L
Sbjct: 206 PKGTSCHN--TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 263

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXX 168
           CP  PG+   + P   V    + D C +H+  C + GTC +   ++ C C   W+     
Sbjct: 264 CP--PGF---IGPDCEV----NPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGWDCS 312

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      P     G C+N  GS+ C+C  G+
Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW 347



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 27/212 (12%)

Query: 3   GFNCT-DVDECKS--PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-G 57
           G++C+ DVDEC++  P  C+ G  C N+ GS+ C C   +   S      D   A C  G
Sbjct: 308 GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG 367

Query: 58  KVDL-RSGTETCR-DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG 115
              + R G+ +C            +   C S        C   P  GS     LC   PG
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST----LCLCQPG 423

Query: 116 YQPVLEPPSYVVTLADIDECA-AHEGL--CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
           Y     P  +     D+DEC  A +G   C HG +C NT GSF C C  G++        
Sbjct: 424 YSG---PTCH----QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--GSRCEA 474

Query: 172 XXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                  +P  C PG  C +L  ++ CLCP G
Sbjct: 475 DHNECLSQP--CHPGSTCLDLLATFHCLCPPG 504



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 54/208 (25%), Positives = 72/208 (34%), Gaps = 31/208 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF+ T    D+DEC+S      GQC +  G++ C+C P +E              RC 
Sbjct: 540 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE------------GPRCQ 587

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGGPG 115
            +VD    ++ C       +      C C  G   G  C+ P   P     +Q+C     
Sbjct: 588 TEVD-ECLSDPCPVGASCLDLPGAFFCLCPSGFT-GQLCEVPLCAPNLCQPKQICKDQKD 645

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               L P          D C  H G C   +         C C  GW+  P         
Sbjct: 646 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---------CVCDVGWT-GPECEAELGGC 695

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C   P  Y C CP GY
Sbjct: 696 ISA-PCAHG-GTCYPQPSGYNCTCPTGY 721



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 63/218 (28%), Positives = 82/218 (37%), Gaps = 32/218 (14%)

Query: 2   PGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCY 56
           PGF   +C  + D C S Q    G C +   +YTC CP  +     G  C  D  +    
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQ 321

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGP- 114
           G    R+G  TC++S      G+    C S    WG     C E   +     C PG   
Sbjct: 322 GPPHCRNGG-TCQNSA-----GSFHCVCVS---GWGG--TSCEENLDDCIAATCAPGSTC 370

Query: 115 ----GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
               G    L PP     L  +++    +       C TN   GS +C C  G+S  P  
Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS-GPTC 429

Query: 169 XXXXXXXXXXR--PDVCGPG-VCRNLPGSYVCLCPEGY 203
                     +  P  C  G  C N PGS+ CLCP GY
Sbjct: 430 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 131 DIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VC 188
           D++EC    G C  GT C NT GSF C C  G    P             P  C  G  C
Sbjct: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GPRCELRAGPCP---PRGCSNGGTC 249

Query: 189 RNLPGS----YVCLCPEGYV 204
           + +P      ++CLCP G++
Sbjct: 250 QLMPEKDSTFHLCLCPPGFI 269



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 52/214 (24%), Positives = 74/214 (34%), Gaps = 27/214 (12%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C++ +  C S      G C  + G Y C CPP++     G  C  S    C      
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTD-YCVSAPCF 777

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE----AYRQLCPGGPGYQ 117
             G  TC     ++  GT  +C C++G   G  C+    P         R  C   P   
Sbjct: 778 NGG--TC-----VNRPGTF-SCLCAMGFQ-GPRCEGKLRPSCADSPCRNRATCQDSPQGP 828

Query: 118 PVLEPPSYV-VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXX 174
             L P  Y   +   + +  A      +  C  T  SF C C  GW+  L          
Sbjct: 829 RCLCPTGYTGGSCQTLMDLCAQRPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQK 888

Query: 175 XXXXR----PDVC-GPGVCRNLPGSYVCLCPEGY 203
               +      +C   G+C +   SY C CP G+
Sbjct: 889 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 51/212 (24%), Positives = 69/212 (32%), Gaps = 28/212 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQ--GSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C   D C S       QC      GS  C C P Y     G  C+      C   + 
Sbjct: 387 GLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLD-EC---LM 438

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
            + G   C              C C  G   G+ C+      +E   Q C  G     +L
Sbjct: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYT-GSRCEA---DHNECLSQPCHPGSTCLDLL 494

Query: 121 E------PPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  PP     L +++  ECA+   L  H  C +    F C C  G+S         
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFS----GTRCE 549

Query: 173 XXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                 R   C   G C++ PG++ C C  G+
Sbjct: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGF 581


>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 61/208 (29%), Positives = 85/208 (40%), Gaps = 32/208 (15%)

Query: 8   DVDEC----KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           D+DEC    + P  C++G  C+NT GS+ C CPP Y     G+ C ++    C  +    
Sbjct: 432 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRC-EADHNECLSQ-PCH 485

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPGYQP 118
            G+ TC D            C C  G   G  C+     C       +        G+Q 
Sbjct: 486 PGS-TCLDLLATFH------CLCPPGLE-GQLCEVETNECASAPCLNHADCHDLLNGFQC 537

Query: 119 VLEPP-SYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
           +  P  S      DIDEC +    CA+G  C +  G+F C C  G+   P          
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFE-GPRCQTEVDECL 594

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
               D C  G  C +LPG++ CLCP G+
Sbjct: 595 S---DPCPVGASCLDLPGAFFCLCPSGF 619



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 55/215 (25%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 1   MPGFN---CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDS---- 50
           MPG+    C   D C +      G C+ T     C CPP +E      D   C+      
Sbjct: 146 MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205

Query: 51  -RKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
            +   C+    L S    C    E       A  C   G + G  C   PE  S  +  L
Sbjct: 206 PKGTSCHN--TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 263

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXX 168
           CP  PG+   + P   V    + D C +H+  C + GTC +   ++ C C   W+     
Sbjct: 264 CP--PGF---IGPDCEV----NPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGWDCS 312

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      P     G C+N  GS+ C+C  G+
Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW 347



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 27/212 (12%)

Query: 3   GFNCT-DVDECKS--PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-G 57
           G++C+ DVDEC++  P  C+ G  C N+ GS+ C C   +   S      D   A C  G
Sbjct: 308 GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG 367

Query: 58  KVDL-RSGTETCR-DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG 115
              + R G+ +C            +   C S        C   P  GS     LC   PG
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST----LCLCQPG 423

Query: 116 YQPVLEPPSYVVTLADIDECA-AHEGL--CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
           Y     P  +     D+DEC  A +G   C HG +C NT GSF C C  G++        
Sbjct: 424 YSG---PTCH----QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--GSRCEA 474

Query: 172 XXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                  +P  C PG  C +L  ++ CLCP G
Sbjct: 475 DHNECLSQP--CHPGSTCLDLLATFHCLCPPG 504



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 54/208 (25%), Positives = 72/208 (34%), Gaps = 31/208 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF+ T    D+DEC+S      GQC +  G++ C+C P +E              RC 
Sbjct: 540 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE------------GPRCQ 587

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGGPG 115
            +VD    ++ C       +      C C  G   G  C+ P   P     +Q+C     
Sbjct: 588 TEVD-ECLSDPCPVGASCLDLPGAFFCLCPSGFT-GQLCEVPLCAPNLCQPKQICKDQKD 645

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               L P          D C  H G C   +         C C  GW+  P         
Sbjct: 646 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---------CVCDVGWT-GPECEAELGGC 695

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C   P  Y C CP GY
Sbjct: 696 ISA-PCAHG-GTCYPQPSGYNCTCPTGY 721



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 63/218 (28%), Positives = 82/218 (37%), Gaps = 32/218 (14%)

Query: 2   PGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCY 56
           PGF   +C  + D C S Q    G C +   +YTC CP  +     G  C  D  +    
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQ 321

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGP- 114
           G    R+G  TC++S      G+    C S    WG     C E   +     C PG   
Sbjct: 322 GPPHCRNGG-TCQNSA-----GSFHCVCVS---GWGG--TSCEENLDDCIAATCAPGSTC 370

Query: 115 ----GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
               G    L PP     L  +++    +       C TN   GS +C C  G+S  P  
Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS-GPTC 429

Query: 169 XXXXXXXXXXR--PDVCGPG-VCRNLPGSYVCLCPEGY 203
                     +  P  C  G  C N PGS+ CLCP GY
Sbjct: 430 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 46/210 (21%), Positives = 69/210 (32%), Gaps = 28/210 (13%)

Query: 7   TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           T  D C S      G C+N  G+++C C   ++              RC GK+       
Sbjct: 766 TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQ------------GPRCEGKLRPSCADS 813

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQPVL--- 120
            CR+     +      C C  G   G+     D C +            GP +  +    
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQG 873

Query: 121 -EPPSYVVTLADIDECAAHEG-----LCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P   + L+   + A  +G     LC + G C ++  S+ C C  G+           
Sbjct: 874 WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHV 931

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                RP   G   C   P  Y+C C  GY
Sbjct: 932 NPCESRPCQNG-ATCMAQPSGYLCQCAPGY 960



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 131 DIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VC 188
           D++EC    G C  GT C NT GSF C C  G    P             P  C  G  C
Sbjct: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GPRCELRAGPCP---PRGCSNGGTC 249

Query: 189 RNLPGS----YVCLCPEGYV 204
           + +P      ++CLCP G++
Sbjct: 250 QLMPEKDSTFHLCLCPPGFI 269



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 52/214 (24%), Positives = 75/214 (35%), Gaps = 27/214 (12%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C++ +  C S      G C  + G Y C CPP++     G  C  S    C      
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTD-YCVSAPCF 777

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE----AYRQLCPGGPGYQ 117
             G  TC     ++  GT  +C C++G   G  C+    P         R  C   P   
Sbjct: 778 NGG--TC-----VNRPGTF-SCLCAMGFQ-GPRCEGKLRPSCADSPCRNRATCQDSPQGP 828

Query: 118 PVLEPPSYV-VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXX 174
             L P  Y   +   + +  A +    +  C  T  SF C C  GW+  L          
Sbjct: 829 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQK 888

Query: 175 XXXXR----PDVC-GPGVCRNLPGSYVCLCPEGY 203
               +      +C   G+C +   SY C CP G+
Sbjct: 889 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/172 (29%), Positives = 64/172 (37%), Gaps = 23/172 (13%)

Query: 2    PGFN---CTD-VDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            PGF    C D V+ C+S + CQ G  C+     Y C+C P Y    DG  C     A C 
Sbjct: 920  PGFQGSLCQDHVNPCES-RPCQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDA-CQ 973

Query: 57   GKVDLRSGTETCRDSDE--LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
             +     GT T +          G +   C   G        PC   G+ A   L     
Sbjct: 974  SQPCHNHGTCTPKPGGFHCACPPGFVGLRC--EGDVDECLDQPCHPTGTAACHSL--ANA 1029

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGS---FVCTCGAGW 162
             Y   L   +      +ID C  H   C H GTC  T GS   F+C C  G+
Sbjct: 1030 FYCQCLPGHTGQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGF 1079



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 51/212 (24%), Positives = 69/212 (32%), Gaps = 28/212 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQ--GSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C   D C S       QC      GS  C C P Y     G  C+      C   + 
Sbjct: 387 GLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLD-EC---LM 438

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
            + G   C              C C  G   G+ C+      +E   Q C  G     +L
Sbjct: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYT-GSRCEA---DHNECLSQPCHPGSTCLDLL 494

Query: 121 E------PPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  PP     L +++  ECA+   L  H  C +    F C C  G+S         
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFS----GTRCE 549

Query: 173 XXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                 R   C   G C++ PG++ C C  G+
Sbjct: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGF 581



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 46/191 (24%), Positives = 69/191 (36%), Gaps = 24/191 (12%)

Query: 21   GQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTM 80
            G C+++  SY C CPP ++    G+ C D     C  +   ++G  TC         G +
Sbjct: 905  GLCVDSGPSYFCHCPPGFQ----GSLCQDHVNP-CESR-PCQNGA-TCM----AQPSGYL 953

Query: 81   AACCCSV-GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLA--DIDECAA 137
              C     G       D C       +    P   G+     PP +V      D+DEC  
Sbjct: 954  CQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDECL- 1011

Query: 138  HEGLCAHGT--CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS- 194
             +     GT  C +   +F C C  G +               +P   G G C    GS 
Sbjct: 1012 DQPCHPTGTAACHSLANAFYCQCLPGHT--GQWCEVEIDPCHSQPCFHG-GTCEATAGSP 1068

Query: 195  --YVCLCPEGY 203
              ++C CP+G+
Sbjct: 1069 LGFICHCPKGF 1079



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 20/87 (22%), Positives = 30/87 (34%), Gaps = 6/87 (6%)

Query: 122  PPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
            PP +  +L            C +G TC      ++C C  G+                + 
Sbjct: 919  PPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD----GQNCSKELDACQS 974

Query: 181  DVC-GPGVCRNLPGSYVCLCPEGYVAM 206
              C   G C   PG + C CP G+V +
Sbjct: 975  QPCHNHGTCTPKPGGFHCACPPGFVGL 1001


>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 61/208 (29%), Positives = 85/208 (40%), Gaps = 32/208 (15%)

Query: 8   DVDEC----KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           D+DEC    + P  C++G  C+NT GS+ C CPP Y     G+ C ++    C  +    
Sbjct: 432 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRC-EADHNECLSQ-PCH 485

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPGYQP 118
            G+ TC D            C C  G   G  C+     C       +        G+Q 
Sbjct: 486 PGS-TCLDLLATFH------CLCPPGLE-GQLCEVETNECASAPCLNHADCHDLLNGFQC 537

Query: 119 VLEPP-SYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
           +  P  S      DIDEC +    CA+G  C +  G+F C C  G+   P          
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFE-GPRCQTEVDECL 594

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
               D C  G  C +LPG++ CLCP G+
Sbjct: 595 S---DPCPVGASCLDLPGAFFCLCPSGF 619



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 55/215 (25%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 1   MPGFN---CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDS---- 50
           MPG+    C   D C +      G C+ T     C CPP +E      D   C+      
Sbjct: 146 MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205

Query: 51  -RKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
            +   C+    L S    C    E       A  C   G + G  C   PE  S  +  L
Sbjct: 206 PKGTSCHN--TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 263

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXX 168
           CP  PG+   + P   V    + D C +H+  C + GTC +   ++ C C   W+     
Sbjct: 264 CP--PGF---IGPDCEV----NPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGWDCS 312

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      P     G C+N  GS+ C+C  G+
Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW 347



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 27/212 (12%)

Query: 3   GFNCT-DVDECKS--PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-G 57
           G++C+ DVDEC++  P  C+ G  C N+ GS+ C C   +   S      D   A C  G
Sbjct: 308 GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG 367

Query: 58  KVDL-RSGTETCR-DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG 115
              + R G+ +C            +   C S        C   P  GS     LC   PG
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST----LCLCQPG 423

Query: 116 YQPVLEPPSYVVTLADIDECA-AHEGL--CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
           Y     P  +     D+DEC  A +G   C HG +C NT GSF C C  G++        
Sbjct: 424 YSG---PTCH----QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--GSRCEA 474

Query: 172 XXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                  +P  C PG  C +L  ++ CLCP G
Sbjct: 475 DHNECLSQP--CHPGSTCLDLLATFHCLCPPG 504



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 54/208 (25%), Positives = 72/208 (34%), Gaps = 31/208 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF+ T    D+DEC+S      GQC +  G++ C+C P +E              RC 
Sbjct: 540 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE------------GPRCQ 587

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGGPG 115
            +VD    ++ C       +      C C  G   G  C+ P   P     +Q+C     
Sbjct: 588 TEVD-ECLSDPCPVGASCLDLPGAFFCLCPSGFT-GQLCEVPLCAPNLCQPKQICKDQKD 645

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               L P          D C  H G C   +         C C  GW+  P         
Sbjct: 646 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---------CVCDVGWT-GPECEAELGGC 695

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C   P  Y C CP GY
Sbjct: 696 ISA-PCAHG-GTCYPQPSGYNCTCPTGY 721



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 63/218 (28%), Positives = 82/218 (37%), Gaps = 32/218 (14%)

Query: 2   PGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCY 56
           PGF   +C  + D C S Q    G C +   +YTC CP  +     G  C  D  +    
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQ 321

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGP- 114
           G    R+G  TC++S      G+    C S    WG     C E   +     C PG   
Sbjct: 322 GPPHCRNGG-TCQNSA-----GSFHCVCVS---GWGG--TSCEENLDDCIAATCAPGSTC 370

Query: 115 ----GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
               G    L PP     L  +++    +       C TN   GS +C C  G+S  P  
Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS-GPTC 429

Query: 169 XXXXXXXXXXR--PDVCGPG-VCRNLPGSYVCLCPEGY 203
                     +  P  C  G  C N PGS+ CLCP GY
Sbjct: 430 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 46/210 (21%), Positives = 69/210 (32%), Gaps = 28/210 (13%)

Query: 7   TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           T  D C S      G C+N  G+++C C   ++              RC GK+       
Sbjct: 766 TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQ------------GPRCEGKLRPSCADS 813

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQPVL--- 120
            CR+     +      C C  G   G+     D C +            GP +  +    
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQG 873

Query: 121 -EPPSYVVTLADIDECAAHEG-----LCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P   + L+   + A  +G     LC + G C ++  S+ C C  G+           
Sbjct: 874 WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHV 931

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                RP   G   C   P  Y+C C  GY
Sbjct: 932 NPCESRPCQNG-ATCMAQPSGYLCQCAPGY 960



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 131 DIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VC 188
           D++EC    G C  GT C NT GSF C C  G    P             P  C  G  C
Sbjct: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GPRCELRAGPCP---PRGCSNGGTC 249

Query: 189 RNLPGS----YVCLCPEGYV 204
           + +P      ++CLCP G++
Sbjct: 250 QLMPEKDSTFHLCLCPPGFI 269



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 52/214 (24%), Positives = 75/214 (35%), Gaps = 27/214 (12%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C++ +  C S      G C  + G Y C CPP++     G  C  S    C      
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTD-YCVSAPCF 777

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE----AYRQLCPGGPGYQ 117
             G  TC     ++  GT  +C C++G   G  C+    P         R  C   P   
Sbjct: 778 NGG--TC-----VNRPGTF-SCLCAMGFQ-GPRCEGKLRPSCADSPCRNRATCQDSPQGP 828

Query: 118 PVLEPPSYV-VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXX 174
             L P  Y   +   + +  A +    +  C  T  SF C C  GW+  L          
Sbjct: 829 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQK 888

Query: 175 XXXXR----PDVC-GPGVCRNLPGSYVCLCPEGY 203
               +      +C   G+C +   SY C CP G+
Sbjct: 889 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/172 (29%), Positives = 64/172 (37%), Gaps = 23/172 (13%)

Query: 2    PGFN---CTD-VDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            PGF    C D V+ C+S + CQ G  C+     Y C+C P Y    DG  C     A C 
Sbjct: 920  PGFQGSLCQDHVNPCES-RPCQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDA-CQ 973

Query: 57   GKVDLRSGTETCRDSDE--LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
             +     GT T +          G +   C   G        PC   G+ A   L     
Sbjct: 974  SQPCHNHGTCTPKPGGFHCACPPGFVGLRC--EGDVDECLDQPCHPTGTAACHSL--ANA 1029

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGS---FVCTCGAGW 162
             Y   L   +      +ID C  H   C H GTC  T GS   F+C C  G+
Sbjct: 1030 FYCQCLPGHTGQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGF 1079



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 51/212 (24%), Positives = 69/212 (32%), Gaps = 28/212 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQ--GSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C   D C S       QC      GS  C C P Y     G  C+      C   + 
Sbjct: 387 GLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLD-EC---LM 438

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
            + G   C              C C  G   G+ C+      +E   Q C  G     +L
Sbjct: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYT-GSRCEA---DHNECLSQPCHPGSTCLDLL 494

Query: 121 E------PPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  PP     L +++  ECA+   L  H  C +    F C C  G+S         
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFS----GTRCE 549

Query: 173 XXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                 R   C   G C++ PG++ C C  G+
Sbjct: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGF 581



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 46/191 (24%), Positives = 69/191 (36%), Gaps = 24/191 (12%)

Query: 21   GQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTM 80
            G C+++  SY C CPP ++    G+ C D     C  +   ++G  TC         G +
Sbjct: 905  GLCVDSGPSYFCHCPPGFQ----GSLCQDHVNP-CESR-PCQNGA-TCM----AQPSGYL 953

Query: 81   AACCCSV-GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLA--DIDECAA 137
              C     G       D C       +    P   G+     PP +V      D+DEC  
Sbjct: 954  CQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDECL- 1011

Query: 138  HEGLCAHGT--CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS- 194
             +     GT  C +   +F C C  G +               +P   G G C    GS 
Sbjct: 1012 DQPCHPTGTAACHSLANAFYCQCLPGHT--GQWCEVEIDPCHSQPCFHG-GTCEATAGSP 1068

Query: 195  --YVCLCPEGY 203
              ++C CP+G+
Sbjct: 1069 LGFICHCPKGF 1079



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 20/87 (22%), Positives = 30/87 (34%), Gaps = 6/87 (6%)

Query: 122  PPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
            PP +  +L            C +G TC      ++C C  G+                + 
Sbjct: 919  PPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD----GQNCSKELDACQS 974

Query: 181  DVC-GPGVCRNLPGSYVCLCPEGYVAM 206
              C   G C   PG + C CP G+V +
Sbjct: 975  QPCHNHGTCTPKPGGFHCACPPGFVGL 1001


>BC063815-1|AAH63815.1|  647|Homo sapiens NOTCH4 protein protein.
          Length = 647

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 61/208 (29%), Positives = 85/208 (40%), Gaps = 32/208 (15%)

Query: 8   DVDEC----KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           D+DEC    + P  C++G  C+NT GS+ C CPP Y     G+ C ++    C  +    
Sbjct: 432 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRC-EADHNECLSQ-PCH 485

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPGYQP 118
            G+ TC D            C C  G   G  C+     C       +        G+Q 
Sbjct: 486 PGS-TCLDLLATFH------CLCPPGLE-GQLCEVETNECASAPCLNHADCHDLLNGFQC 537

Query: 119 VLEPP-SYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
           +  P  S      DIDEC +    CA+G  C +  G+F C C  G+   P          
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFE-GPRCQTEVDECL 594

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
               D C  G  C +LPG++ CLCP G+
Sbjct: 595 S---DPCPVGASCLDLPGAFFCLCPSGF 619



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 55/215 (25%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 1   MPGFN---CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDS---- 50
           MPG+    C   D C +      G C+ T     C CPP +E      D   C+      
Sbjct: 146 MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205

Query: 51  -RKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
            +   C+    L S    C    E       A  C   G + G  C   PE  S  +  L
Sbjct: 206 PKGTSCHN--TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 263

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXX 168
           CP  PG+   + P   V    + D C +H+  C + GTC +   ++ C C   W+     
Sbjct: 264 CP--PGF---IGPDCEV----NPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGWDCS 312

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      P     G C+N  GS+ C+C  G+
Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW 347



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 27/212 (12%)

Query: 3   GFNCT-DVDECKS--PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-G 57
           G++C+ DVDEC++  P  C+ G  C N+ GS+ C C   +   S      D   A C  G
Sbjct: 308 GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG 367

Query: 58  KVDL-RSGTETCR-DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG 115
              + R G+ +C            +   C S        C   P  GS     LC   PG
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST----LCLCQPG 423

Query: 116 YQPVLEPPSYVVTLADIDECA-AHEGL--CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
           Y     P  +     D+DEC  A +G   C HG +C NT GSF C C  G++        
Sbjct: 424 YSG---PTCH----QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--GSRCEA 474

Query: 172 XXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                  +P  C PG  C +L  ++ CLCP G
Sbjct: 475 DHNECLSQP--CHPGSTCLDLLATFHCLCPPG 504



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 63/218 (28%), Positives = 82/218 (37%), Gaps = 32/218 (14%)

Query: 2   PGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCY 56
           PGF   +C  + D C S Q    G C +   +YTC CP  +     G  C  D  +    
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQ 321

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGP- 114
           G    R+G  TC++S      G+    C S    WG     C E   +     C PG   
Sbjct: 322 GPPHCRNGG-TCQNSA-----GSFHCVCVS---GWGG--TSCEENLDDCIAATCAPGSTC 370

Query: 115 ----GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
               G    L PP     L  +++    +       C TN   GS +C C  G+S  P  
Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS-GPTC 429

Query: 169 XXXXXXXXXXR--PDVCGPG-VCRNLPGSYVCLCPEGY 203
                     +  P  C  G  C N PGS+ CLCP GY
Sbjct: 430 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 131 DIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VC 188
           D++EC    G C  GT C NT GSF C C  G    P             P  C  G  C
Sbjct: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GPRCELRAGPCP---PRGCSNGGTC 249

Query: 189 RNLPGS----YVCLCPEGYV 204
           + +P      ++CLCP G++
Sbjct: 250 QLMPEKDSTFHLCLCPPGFI 269



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 4/43 (9%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYE 39
           +PGF+ T    D+DEC+S      GQC +  G++ C+C P +E
Sbjct: 540 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE 582



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 51/212 (24%), Positives = 69/212 (32%), Gaps = 28/212 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQ--GSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C   D C S       QC      GS  C C P Y     G  C+      C   + 
Sbjct: 387 GLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLD-EC---LM 438

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
            + G   C              C C  G   G+ C+      +E   Q C  G     +L
Sbjct: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYT-GSRCEA---DHNECLSQPCHPGSTCLDLL 494

Query: 121 E------PPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  PP     L +++  ECA+   L  H  C +    F C C  G+S         
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFS----GTRCE 549

Query: 173 XXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                 R   C   G C++ PG++ C C  G+
Sbjct: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGF 581



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 6/43 (13%)

Query: 1   MPGFN---C-TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNY 38
           +PGF    C T+VDEC S   C  G  C++  G++ C CP  +
Sbjct: 578 LPGFEGPRCQTEVDECLS-DPCPVGASCLDLPGAFFCLCPSGF 619


>BC053357-1|AAH53357.1|  575|Homo sapiens thrombomodulin protein.
          Length = 575

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 56/169 (33%), Positives = 79/169 (46%), Gaps = 27/169 (15%)

Query: 6   CTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR----KARC-YGKV 59
           C DVD+C   P  C   +C+NTQG + C C PNY+LV DG  C +      +A C Y   
Sbjct: 323 CEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLV-DGE-CVEPVDPCFRANCEYQCQ 379

Query: 60  DLRSGTETCRDSD---ELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            L   +  C  ++    +  +       C+  A   + CDP  +   E     CP   GY
Sbjct: 380 PLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-CDPNTQASCE-----CP--EGY 431

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
             +L+   ++ T  DIDEC  + G C+ G C N  G+F C CG   +LA
Sbjct: 432 --ILDD-GFICT--DIDECE-NGGFCS-GVCHNLPGTFECICGPDSALA 473



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/51 (45%), Positives = 29/51 (56%), Gaps = 3/51 (5%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSD-GTACYDSRK 52
           GF CTD+DEC++   C  G C N  G++ C C P+  L    GT C DS K
Sbjct: 436 GFICTDIDECENGGFCS-GVCHNLPGTFECICGPDSALARHIGTDC-DSGK 484



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 3/72 (4%)

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN--L 191
           +C+   G C H  C    G+  C C AG +L                D+C      N   
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302

Query: 192 PGSYVCLCPEGY 203
           PGSY C+C  GY
Sbjct: 303 PGSYSCMCETGY 314



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 50/191 (26%), Positives = 73/191 (38%), Gaps = 24/191 (12%)

Query: 28  GSYTCRCPPNYELVSDGTACYDS-----RKARCYGK-VDLRSGTET-CRDSDELSEDGTM 80
           GSY+C C   Y L +D   C D        + C  + V+ + G E  C  + +L  DG  
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGE- 361

Query: 81  AACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
             C   V   +   C+   +P ++    LC    G+ P+   P       +   C A   
Sbjct: 362 --CVEPVDPCFRANCEYQCQPLNQT-SYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-- 416

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC- 199
            C      NT  S  C C  G+ L                  C  GVC NLPG++ C+C 
Sbjct: 417 -CD----PNTQAS--CECPEGYIL-DDGFICTDIDECENGGFCS-GVCHNLPGTFECICG 467

Query: 200 PEGYVAMPNGS 210
           P+  +A   G+
Sbjct: 468 PDSALARHIGT 478



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 35/139 (25%), Positives = 43/139 (30%), Gaps = 15/139 (10%)

Query: 78  GTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADI 132
           G    C    GA  G++    P        +      C   PG  P  + P+     AD 
Sbjct: 219 GLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPG-APRCQCPAGAALQADG 277

Query: 133 DECAAH-----EGLCAHGTCTNTF--GSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCG 184
             C A        LC H    N    GS+ C C  G+ LA               P  C 
Sbjct: 278 RSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC- 336

Query: 185 PGVCRNLPGSYVCLCPEGY 203
           P  C N  G + C C   Y
Sbjct: 337 PQRCVNTQGGFECHCYPNY 355


>BC038587-1|AAH38587.1|  553|Homo sapiens EGF-like-domain, multiple
           6 protein.
          Length = 553

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 54/171 (31%), Positives = 71/171 (41%), Gaps = 18/171 (10%)

Query: 3   GFNCT-DVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA---RC-Y 56
           G  C+ DV+EC   P+ CQ+ +C+NT GSY C C   + L+ D T C +SR      C Y
Sbjct: 88  GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDAT-CVNSRTCAMINCQY 145

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
              D   G +    S  L        C     C+ G     Y   C       Y   C  
Sbjct: 146 SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYY---CKC 202

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGW 162
             G++  L+  S      DI+EC      C+ H  C NT GSF C C  G+
Sbjct: 203 HIGFE--LQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 58/208 (27%), Positives = 77/208 (37%), Gaps = 21/208 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDSRKARCYGKVDL 61
           N   V E      C++G+C+   G   CRC P Y       D   C    +   +  V+ 
Sbjct: 56  NSKGVCEATCEPGCKFGECV---GPNKCRCFPGYTGKTCSQDVNECGMKPRPCQHRCVNT 112

Query: 62  RSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
               +  C     L  D T   C  S   A  N C    E   E  + LCP   G +  L
Sbjct: 113 HGSYKCFCLSGHMLMPDAT---CVNSRTCAMIN-CQYSCEDTEEGPQCLCPSS-GLR--L 165

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSL---APXXXXXXXXXX 176
            P        DIDECA+ + +C +   C NTFGS+ C C  G+ L   +           
Sbjct: 166 APNGR--DCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC 223

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
                 C     C N  GS+ C C +GY
Sbjct: 224 TMDSHTCSHHANCFNTQGSFKCKCKQGY 251



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 36/137 (26%), Positives = 46/137 (33%), Gaps = 8/137 (5%)

Query: 78  GTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
           GT  ACC          C+   EPG +    +   GP         +      D++EC  
Sbjct: 44  GTKLACCYGWRRNSKGVCEATCEPGCKFGECV---GPNKCRCFPGYTGKTCSQDVNECGM 100

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVC 197
               C H  C NT GS+ C C +G  L P               +     C +      C
Sbjct: 101 KPRPCQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAM---INCQYSCEDTEEGPQC 156

Query: 198 LCP-EGYVAMPNGSQYL 213
           LCP  G    PNG   L
Sbjct: 157 LCPSSGLRLAPNGRDCL 173



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 4/46 (8%)

Query: 4   FNCTDVDECK-SPQSCQY-GQCINTQGSYTCRCPPNYELVSDGTAC 47
           ++C D++EC     +C +   C NTQGS+ C+C   Y+   +G  C
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK--GNGLRC 258


>AY358333-1|AAQ88699.1|  338|Homo sapiens EGFL6 protein.
          Length = 338

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 54/171 (31%), Positives = 71/171 (41%), Gaps = 18/171 (10%)

Query: 3   GFNCT-DVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA---RC-Y 56
           G  C+ DV+EC   P+ CQ+ +C+NT GSY C C   + L+ D T C +SR      C Y
Sbjct: 88  GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDAT-CVNSRTCAMINCQY 145

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
              D   G +    S  L        C     C+ G     Y   C       Y   C  
Sbjct: 146 SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYY---CKC 202

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGW 162
             G++  L+  S      DI+EC      C+ H  C NT GSF C C  G+
Sbjct: 203 HIGFE--LQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 58/208 (27%), Positives = 77/208 (37%), Gaps = 21/208 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDSRKARCYGKVDL 61
           N   V E      C++G+C+   G   CRC P Y       D   C    +   +  V+ 
Sbjct: 56  NSKGVCEATCEPGCKFGECV---GPNKCRCFPGYTGKTCSQDVNECGMKPRPCQHRCVNT 112

Query: 62  RSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
               +  C     L  D T   C  S   A  N C    E   E  + LCP   G +  L
Sbjct: 113 HGSYKCFCLSGHMLMPDAT---CVNSRTCAMIN-CQYSCEDTEEGPQCLCPSS-GLR--L 165

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSL---APXXXXXXXXXX 176
            P        DIDECA+ + +C +   C NTFGS+ C C  G+ L   +           
Sbjct: 166 APNGR--DCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC 223

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
                 C     C N  GS+ C C +GY
Sbjct: 224 TMDSHTCSHHANCFNTQGSFKCKCKQGY 251



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 36/137 (26%), Positives = 46/137 (33%), Gaps = 8/137 (5%)

Query: 78  GTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
           GT  ACC          C+   EPG +    +   GP         +      D++EC  
Sbjct: 44  GTKLACCYGWRRNSKGVCEATCEPGCKFGECV---GPNKCRCFPGYTGKTCSQDVNECGM 100

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVC 197
               C H  C NT GS+ C C +G  L P               +     C +      C
Sbjct: 101 KPRPCQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAM---INCQYSCEDTEEGPQC 156

Query: 198 LCP-EGYVAMPNGSQYL 213
           LCP  G    PNG   L
Sbjct: 157 LCPSSGLRLAPNGRDCL 173



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 4/46 (8%)

Query: 4   FNCTDVDECK-SPQSCQY-GQCINTQGSYTCRCPPNYELVSDGTAC 47
           ++C D++EC     +C +   C NTQGS+ C+C   Y+   +G  C
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK--GNGLRC 258


>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 61/208 (29%), Positives = 85/208 (40%), Gaps = 32/208 (15%)

Query: 8   DVDEC----KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           D+DEC    + P  C++G  C+NT GS+ C CPP Y     G+ C ++    C  +    
Sbjct: 432 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRC-EADHNECLSQ-PCH 485

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPGYQP 118
            G+ TC D            C C  G   G  C+     C       +        G+Q 
Sbjct: 486 PGS-TCLDLLATFH------CLCPPGLE-GQLCEVETNECASAPCLNHADCHDLLNGFQC 537

Query: 119 VLEPP-SYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
           +  P  S      DIDEC +    CA+G  C +  G+F C C  G+   P          
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFE-GPRCQTEVDECL 594

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
               D C  G  C +LPG++ CLCP G+
Sbjct: 595 S---DPCPVGASCLDLPGAFFCLCPSGF 619



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 55/215 (25%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 1   MPGFN---CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDS---- 50
           MPG+    C   D C +      G C+ T     C CPP +E      D   C+      
Sbjct: 146 MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205

Query: 51  -RKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
            +   C+    L S    C    E       A  C   G + G  C   PE  S  +  L
Sbjct: 206 PKGTSCHN--TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 263

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXX 168
           CP  PG+   + P   V    + D C +H+  C + GTC +   ++ C C   W+     
Sbjct: 264 CP--PGF---IGPDCEV----NPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGWDCS 312

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      P     G C+N  GS+ C+C  G+
Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW 347



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 27/212 (12%)

Query: 3   GFNCT-DVDECKS--PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-G 57
           G++C+ DVDEC++  P  C+ G  C N+ GS+ C C   +   S      D   A C  G
Sbjct: 308 GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG 367

Query: 58  KVDL-RSGTETCR-DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG 115
              + R G+ +C            +   C S        C   P  GS     LC   PG
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST----LCLCQPG 423

Query: 116 YQPVLEPPSYVVTLADIDECA-AHEGL--CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
           Y     P  +     D+DEC  A +G   C HG +C NT GSF C C  G++        
Sbjct: 424 YSG---PTCH----QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--GSRCEA 474

Query: 172 XXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                  +P  C PG  C +L  ++ CLCP G
Sbjct: 475 DHNECLSQP--CHPGSTCLDLLATFHCLCPPG 504



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 54/208 (25%), Positives = 72/208 (34%), Gaps = 31/208 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF+ T    D+DEC+S      GQC +  G++ C+C P +E              RC 
Sbjct: 540 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE------------GPRCQ 587

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGGPG 115
            +VD    ++ C       +      C C  G   G  C+ P   P     +Q+C     
Sbjct: 588 TEVD-ECLSDPCPVGASCLDLPGAFFCLCPSGFT-GQLCEVPLCAPNLCQPKQICKDQKD 645

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               L P          D C  H G C   +         C C  GW+  P         
Sbjct: 646 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---------CVCDVGWT-GPECEAELGGC 695

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C   P  Y C CP GY
Sbjct: 696 ISA-PCAHG-GTCYPQPSGYNCTCPTGY 721



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 63/218 (28%), Positives = 82/218 (37%), Gaps = 32/218 (14%)

Query: 2   PGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCY 56
           PGF   +C  + D C S Q    G C +   +YTC CP  +     G  C  D  +    
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQ 321

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGP- 114
           G    R+G  TC++S      G+    C S    WG     C E   +     C PG   
Sbjct: 322 GPPHCRNGG-TCQNSA-----GSFHCVCVS---GWGG--TSCEENLDDCIAATCAPGSTC 370

Query: 115 ----GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
               G    L PP     L  +++    +       C TN   GS +C C  G+S  P  
Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS-GPTC 429

Query: 169 XXXXXXXXXXR--PDVCGPG-VCRNLPGSYVCLCPEGY 203
                     +  P  C  G  C N PGS+ CLCP GY
Sbjct: 430 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 131 DIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VC 188
           D++EC    G C  GT C NT GSF C C  G    P             P  C  G  C
Sbjct: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GPRCELRAGPCP---PRGCSNGGTC 249

Query: 189 RNLPGS----YVCLCPEGYV 204
           + +P      ++CLCP G++
Sbjct: 250 QLMPEKDSTFHLCLCPPGFI 269



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 45/210 (21%), Positives = 68/210 (32%), Gaps = 28/210 (13%)

Query: 7   TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           T  D C S      G C+N  G+++C C   ++              RC GK+       
Sbjct: 766 TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQ------------GPRCEGKLRPSCADS 813

Query: 67  TCRDSDELSEDGTMAACCCS---VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL--- 120
            CR+     +      C C     G +     D C +            GP +  +    
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQG 873

Query: 121 -EPPSYVVTLADIDECAAHEG-----LCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P   + L+   + A  +G     LC + G C ++  S+ C C  G+           
Sbjct: 874 WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHV 931

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                RP   G   C   P  Y+C C  GY
Sbjct: 932 NPCESRPCQNG-ATCMAQPSGYLCQCAPGY 960



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 52/214 (24%), Positives = 75/214 (35%), Gaps = 27/214 (12%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C++ +  C S      G C  + G Y C CPP++     G  C  S    C      
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTD-YCVSAPCF 777

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE----AYRQLCPGGPGYQ 117
             G  TC     ++  GT  +C C++G   G  C+    P         R  C   P   
Sbjct: 778 NGG--TC-----VNRPGTF-SCLCAMGFQ-GPRCEGKLRPSCADSPCRNRATCQDSPQGP 828

Query: 118 PVLEPPSYV-VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXX 174
             L P  Y   +   + +  A +    +  C  T  SF C C  GW+  L          
Sbjct: 829 RCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQK 888

Query: 175 XXXXR----PDVC-GPGVCRNLPGSYVCLCPEGY 203
               +      +C   G+C +   SY C CP G+
Sbjct: 889 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/172 (29%), Positives = 64/172 (37%), Gaps = 23/172 (13%)

Query: 2    PGFN---CTD-VDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            PGF    C D V+ C+S + CQ G  C+     Y C+C P Y    DG  C     A C 
Sbjct: 920  PGFQGSLCQDHVNPCES-RPCQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDA-CQ 973

Query: 57   GKVDLRSGTETCRDSDE--LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
             +     GT T +          G +   C   G        PC   G+ A   L     
Sbjct: 974  SQPCHNHGTCTPKPGGFHCACPPGFVGLRC--EGDVDECLDQPCHPTGTAACHSL--ANA 1029

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGS---FVCTCGAGW 162
             Y   L   +      +ID C  H   C H GTC  T GS   F+C C  G+
Sbjct: 1030 FYCQCLPGHTGQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGF 1079



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 51/212 (24%), Positives = 69/212 (32%), Gaps = 28/212 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQ--GSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C   D C S       QC      GS  C C P Y     G  C+      C   + 
Sbjct: 387 GLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLD-EC---LM 438

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
            + G   C              C C  G   G+ C+      +E   Q C  G     +L
Sbjct: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYT-GSRCEA---DHNECLSQPCHPGSTCLDLL 494

Query: 121 E------PPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  PP     L +++  ECA+   L  H  C +    F C C  G+S         
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFS----GTRCE 549

Query: 173 XXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                 R   C   G C++ PG++ C C  G+
Sbjct: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGF 581



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 46/191 (24%), Positives = 69/191 (36%), Gaps = 24/191 (12%)

Query: 21   GQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTM 80
            G C+++  SY C CPP ++    G+ C D     C  +   ++G  TC         G +
Sbjct: 905  GLCVDSGPSYFCHCPPGFQ----GSLCQDHVNP-CESR-PCQNGA-TCM----AQPSGYL 953

Query: 81   AACCCSV-GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLA--DIDECAA 137
              C     G       D C       +    P   G+     PP +V      D+DEC  
Sbjct: 954  CQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDECL- 1011

Query: 138  HEGLCAHGT--CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS- 194
             +     GT  C +   +F C C  G +               +P   G G C    GS 
Sbjct: 1012 DQPCHPTGTAACHSLANAFYCQCLPGHT--GQWCEVEIDPCHSQPCFHG-GTCEATAGSP 1068

Query: 195  --YVCLCPEGY 203
              ++C CP+G+
Sbjct: 1069 LGFICHCPKGF 1079



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 20/87 (22%), Positives = 30/87 (34%), Gaps = 6/87 (6%)

Query: 122  PPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
            PP +  +L            C +G TC      ++C C  G+                + 
Sbjct: 919  PPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD----GQNCSKELDACQS 974

Query: 181  DVC-GPGVCRNLPGSYVCLCPEGYVAM 206
              C   G C   PG + C CP G+V +
Sbjct: 975  QPCHNHGTCTPKPGGFHCACPPGFVGL 1001


>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 61/208 (29%), Positives = 85/208 (40%), Gaps = 32/208 (15%)

Query: 8   DVDEC----KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           D+DEC    + P  C++G  C+NT GS+ C CPP Y     G+ C ++    C  +    
Sbjct: 432 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRC-EADHNECLSQ-PCH 485

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPGYQP 118
            G+ TC D            C C  G   G  C+     C       +        G+Q 
Sbjct: 486 PGS-TCLDLLATFH------CLCPPGLE-GQLCEVETNECASAPCLNHADCHDLLNGFQC 537

Query: 119 VLEPP-SYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
           +  P  S      DIDEC +    CA+G  C +  G+F C C  G+   P          
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFE-GPRCQTEVDECL 594

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
               D C  G  C +LPG++ CLCP G+
Sbjct: 595 S---DPCPVGASCLDLPGAFFCLCPSGF 619



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 55/215 (25%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 1   MPGFN---CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDS---- 50
           MPG+    C   D C +      G C+ T     C CPP +E      D   C+      
Sbjct: 146 MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205

Query: 51  -RKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
            +   C+    L S    C    E       A  C   G + G  C   PE  S  +  L
Sbjct: 206 PKGTSCHN--TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 263

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXX 168
           CP  PG+   + P   V    + D C +H+  C + GTC +   ++ C C   W+     
Sbjct: 264 CP--PGF---IGPDCEV----NPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGWDCS 312

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      P     G C+N  GS+ C+C  G+
Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW 347



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 27/212 (12%)

Query: 3   GFNCT-DVDECKS--PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-G 57
           G++C+ DVDEC++  P  C+ G  C N+ GS+ C C   +   S      D   A C  G
Sbjct: 308 GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG 367

Query: 58  KVDL-RSGTETCR-DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG 115
              + R G+ +C            +   C S        C   P  GS     LC   PG
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST----LCLCQPG 423

Query: 116 YQPVLEPPSYVVTLADIDECA-AHEGL--CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
           Y     P  +     D+DEC  A +G   C HG +C NT GSF C C  G++        
Sbjct: 424 YSG---PTCH----QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--GSRCEA 474

Query: 172 XXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                  +P  C PG  C +L  ++ CLCP G
Sbjct: 475 DHNECLSQP--CHPGSTCLDLLATFHCLCPPG 504



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 54/208 (25%), Positives = 72/208 (34%), Gaps = 31/208 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF+ T    D+DEC+S      GQC +  G++ C+C P +E              RC 
Sbjct: 540 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE------------GPRCQ 587

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGGPG 115
            +VD    ++ C       +      C C  G   G  C+ P   P     +Q+C     
Sbjct: 588 TEVD-ECLSDPCPVGASCLDLPGAFFCLCPSGFT-GQLCEVPLCAPNLCQPKQICKDQKD 645

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               L P          D C  H G C   +         C C  GW+  P         
Sbjct: 646 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---------CVCDVGWT-GPECEAELGGC 695

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C   P  Y C CP GY
Sbjct: 696 ISA-PCAHG-GTCYPQPSGYNCTCPTGY 721



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 63/218 (28%), Positives = 82/218 (37%), Gaps = 32/218 (14%)

Query: 2   PGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCY 56
           PGF   +C  + D C S Q    G C +   +YTC CP  +     G  C  D  +    
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQ 321

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGP- 114
           G    R+G  TC++S      G+    C S    WG     C E   +     C PG   
Sbjct: 322 GPPHCRNGG-TCQNSA-----GSFHCVCVS---GWGG--TSCEENLDDCIAATCAPGSTC 370

Query: 115 ----GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
               G    L PP     L  +++    +       C TN   GS +C C  G+S  P  
Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS-GPTC 429

Query: 169 XXXXXXXXXXR--PDVCGPG-VCRNLPGSYVCLCPEGY 203
                     +  P  C  G  C N PGS+ CLCP GY
Sbjct: 430 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 131 DIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VC 188
           D++EC    G C  GT C NT GSF C C  G    P             P  C  G  C
Sbjct: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GPRCELRAGPCP---PRGCSNGGTC 249

Query: 189 RNLPGS----YVCLCPEGYV 204
           + +P      ++CLCP G++
Sbjct: 250 QLMPEKDSTFHLCLCPPGFI 269



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 45/210 (21%), Positives = 68/210 (32%), Gaps = 28/210 (13%)

Query: 7   TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           T  D C S      G C+N  G+++C C   ++              RC GK+       
Sbjct: 766 TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQ------------GPRCEGKLRPSCADS 813

Query: 67  TCRDSDELSEDGTMAACCCS---VGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL--- 120
            CR+     +      C C     G +     D C +            GP +  +    
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQG 873

Query: 121 -EPPSYVVTLADIDECAAHEG-----LCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P   + L+   + A  +G     LC + G C ++  S+ C C  G+           
Sbjct: 874 WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHV 931

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                RP   G   C   P  Y+C C  GY
Sbjct: 932 NPCESRPCQNG-ATCMAQPSGYLCQCAPGY 960



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 52/214 (24%), Positives = 75/214 (35%), Gaps = 27/214 (12%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C++ +  C S      G C  + G Y C CPP++     G  C  S    C      
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTD-YCVSAPCF 777

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE----AYRQLCPGGPGYQ 117
             G  TC     ++  GT  +C C++G   G  C+    P         R  C   P   
Sbjct: 778 NGG--TC-----VNRPGTF-SCLCAMGFQ-GPRCEGKLRPSCADSPCRNRATCQDSPQGP 828

Query: 118 PVLEPPSYV-VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXX 174
             L P  Y   +   + +  A +    +  C  T  SF C C  GW+  L          
Sbjct: 829 RCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQK 888

Query: 175 XXXXR----PDVC-GPGVCRNLPGSYVCLCPEGY 203
               +      +C   G+C +   SY C CP G+
Sbjct: 889 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/172 (29%), Positives = 64/172 (37%), Gaps = 23/172 (13%)

Query: 2    PGFN---CTD-VDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            PGF    C D V+ C+S + CQ G  C+     Y C+C P Y    DG  C     A C 
Sbjct: 920  PGFQGSLCQDHVNPCES-RPCQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDA-CQ 973

Query: 57   GKVDLRSGTETCRDSDE--LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
             +     GT T +          G +   C   G        PC   G+ A   L     
Sbjct: 974  SQPCHNHGTCTPKPGGFHCACPPGFVGLRC--EGDVDECLDQPCHPTGTAACHSL--ANA 1029

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGS---FVCTCGAGW 162
             Y   L   +      +ID C  H   C H GTC  T GS   F+C C  G+
Sbjct: 1030 FYCQCLPGHTGQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGF 1079



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 51/212 (24%), Positives = 69/212 (32%), Gaps = 28/212 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQ--GSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C   D C S       QC      GS  C C P Y     G  C+      C   + 
Sbjct: 387 GLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLD-EC---LM 438

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
            + G   C              C C  G   G+ C+      +E   Q C  G     +L
Sbjct: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYT-GSRCEA---DHNECLSQPCHPGSTCLDLL 494

Query: 121 E------PPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  PP     L +++  ECA+   L  H  C +    F C C  G+S         
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFS----GTRCE 549

Query: 173 XXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                 R   C   G C++ PG++ C C  G+
Sbjct: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGF 581



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 46/191 (24%), Positives = 69/191 (36%), Gaps = 24/191 (12%)

Query: 21   GQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTM 80
            G C+++  SY C CPP ++    G+ C D     C  +   ++G  TC         G +
Sbjct: 905  GLCVDSGPSYFCHCPPGFQ----GSLCQDHVNP-CESR-PCQNGA-TCM----AQPSGYL 953

Query: 81   AACCCSV-GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLA--DIDECAA 137
              C     G       D C       +    P   G+     PP +V      D+DEC  
Sbjct: 954  CQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDECL- 1011

Query: 138  HEGLCAHGT--CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS- 194
             +     GT  C +   +F C C  G +               +P   G G C    GS 
Sbjct: 1012 DQPCHPTGTAACHSLANAFYCQCLPGHT--GQWCEVEIDPCHSQPCFHG-GTCEATAGSP 1068

Query: 195  --YVCLCPEGY 203
              ++C CP+G+
Sbjct: 1069 LGFICHCPKGF 1079



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 20/87 (22%), Positives = 30/87 (34%), Gaps = 6/87 (6%)

Query: 122  PPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
            PP +  +L            C +G TC      ++C C  G+                + 
Sbjct: 919  PPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD----GQNCSKELDACQS 974

Query: 181  DVC-GPGVCRNLPGSYVCLCPEGYVAM 206
              C   G C   PG + C CP G+V +
Sbjct: 975  QPCHNHGTCTPKPGGFHCACPPGFVGL 1001


>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 61/208 (29%), Positives = 85/208 (40%), Gaps = 32/208 (15%)

Query: 8   DVDEC----KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           D+DEC    + P  C++G  C+NT GS+ C CPP Y     G+ C ++    C  +    
Sbjct: 432 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRC-EADHNECLSQ-PCH 485

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPGYQP 118
            G+ TC D            C C  G   G  C+     C       +        G+Q 
Sbjct: 486 PGS-TCLDLLATFH------CLCPPGLE-GQLCEVETNECASAPCLNHADCHDLLNGFQC 537

Query: 119 VLEPP-SYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
           +  P  S      DIDEC +    CA+G  C +  G+F C C  G+   P          
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFE-GPRCQTEVDECL 594

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
               D C  G  C +LPG++ CLCP G+
Sbjct: 595 S---DPCPVGASCLDLPGAFFCLCPSGF 619



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 55/215 (25%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 1   MPGFN---CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDS---- 50
           MPG+    C   D C +      G C+ T     C CPP +E      D   C+      
Sbjct: 146 MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205

Query: 51  -RKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
            +   C+    L S    C    E       A  C   G + G  C   PE  S  +  L
Sbjct: 206 PKGTSCHN--TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 263

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXX 168
           CP  PG+   + P   V    + D C +H+  C + GTC +   ++ C C   W+     
Sbjct: 264 CP--PGF---IGPDCEV----NPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGWDCS 312

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      P     G C+N  GS+ C+C  G+
Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW 347



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 27/212 (12%)

Query: 3   GFNCT-DVDECKS--PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-G 57
           G++C+ DVDEC++  P  C+ G  C N+ GS+ C C   +   S      D   A C  G
Sbjct: 308 GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG 367

Query: 58  KVDL-RSGTETCR-DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG 115
              + R G+ +C            +   C S        C   P  GS     LC   PG
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST----LCLCQPG 423

Query: 116 YQPVLEPPSYVVTLADIDECA-AHEGL--CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
           Y     P  +     D+DEC  A +G   C HG +C NT GSF C C  G++        
Sbjct: 424 YSG---PTCH----QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--GSRCEA 474

Query: 172 XXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                  +P  C PG  C +L  ++ CLCP G
Sbjct: 475 DHNECLSQP--CHPGSTCLDLLATFHCLCPPG 504



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 54/208 (25%), Positives = 72/208 (34%), Gaps = 31/208 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF+ T    D+DEC+S      GQC +  G++ C+C P +E              RC 
Sbjct: 540 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE------------GPRCQ 587

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGGPG 115
            +VD    ++ C       +      C C  G   G  C+ P   P     +Q+C     
Sbjct: 588 TEVD-ECLSDPCPVGASCLDLPGAFFCLCPSGFT-GQLCEVPLCAPNLCQPKQICKDQKD 645

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               L P          D C  H G C   +         C C  GW+  P         
Sbjct: 646 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---------CVCDVGWT-GPECEAELGGC 695

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C   P  Y C CP GY
Sbjct: 696 ISA-PCAHG-GTCYPQPSGYNCTCPTGY 721



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 63/218 (28%), Positives = 82/218 (37%), Gaps = 32/218 (14%)

Query: 2   PGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCY 56
           PGF   +C  + D C S Q    G C +   +YTC CP  +     G  C  D  +    
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECETQ 321

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGP- 114
           G    R+G  TC++S      G+    C S    WG     C E   +     C PG   
Sbjct: 322 GPPHCRNGG-TCQNSA-----GSFHCVCVS---GWGG--TSCEENLDDCIAATCAPGSTC 370

Query: 115 ----GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
               G    L PP     L  +++    +       C TN   GS +C C  G+S  P  
Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS-GPTC 429

Query: 169 XXXXXXXXXXR--PDVCGPG-VCRNLPGSYVCLCPEGY 203
                     +  P  C  G  C N PGS+ CLCP GY
Sbjct: 430 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 46/210 (21%), Positives = 69/210 (32%), Gaps = 28/210 (13%)

Query: 7   TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           T  D C S      G C+N  G+++C C   ++              RC GK+       
Sbjct: 766 TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQ------------GPRCEGKLRPSCADS 813

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQPVL--- 120
            CR+     +      C C  G   G+     D C +            GP +  +    
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQG 873

Query: 121 -EPPSYVVTLADIDECAAHEG-----LCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P   + L+   + A  +G     LC + G C ++  S+ C C  G+           
Sbjct: 874 WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHV 931

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                RP   G   C   P  Y+C C  GY
Sbjct: 932 NPCESRPCQNG-ATCMAQPSGYLCQCAPGY 960



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 131 DIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VC 188
           D++EC    G C  GT C NT GSF C C  G    P             P  C  G  C
Sbjct: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GPRCELRAGPCP---PRGCSNGGTC 249

Query: 189 RNLPGS----YVCLCPEGYV 204
           + +P      ++CLCP G++
Sbjct: 250 QLMPEKDSTFHLCLCPPGFI 269



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 52/214 (24%), Positives = 75/214 (35%), Gaps = 27/214 (12%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C++ +  C S      G C  + G Y C CPP++     G  C  S    C      
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTD-YCVSAPCF 777

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE----AYRQLCPGGPGYQ 117
             G  TC     ++  GT  +C C++G   G  C+    P         R  C   P   
Sbjct: 778 NGG--TC-----VNRPGTF-SCLCAMGFQ-GPRCEGKLRPSCADSPCRNRATCQDSPQGP 828

Query: 118 PVLEPPSYV-VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXX 174
             L P  Y   +   + +  A +    +  C  T  SF C C  GW+  L          
Sbjct: 829 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQK 888

Query: 175 XXXXR----PDVC-GPGVCRNLPGSYVCLCPEGY 203
               +      +C   G+C +   SY C CP G+
Sbjct: 889 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/172 (29%), Positives = 64/172 (37%), Gaps = 23/172 (13%)

Query: 2    PGFN---CTD-VDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            PGF    C D V+ C+S + CQ G  C+     Y C+C P Y    DG  C     A C 
Sbjct: 920  PGFQGSLCQDHVNPCES-RPCQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDA-CQ 973

Query: 57   GKVDLRSGTETCRDSDE--LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
             +     GT T +          G +   C   G        PC   G+ A   L     
Sbjct: 974  SQPCHNHGTCTPKPGGFHCACPPGFVGLRC--EGDVDECLDQPCHPTGTAACHSL--ANA 1029

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGS---FVCTCGAGW 162
             Y   L   +      +ID C  H   C H GTC  T GS   F+C C  G+
Sbjct: 1030 FYCQCLPGHTGQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGF 1079



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 51/212 (24%), Positives = 69/212 (32%), Gaps = 28/212 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQ--GSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C   D C S       QC      GS  C C P Y     G  C+      C   + 
Sbjct: 387 GLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLD-EC---LM 438

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
            + G   C              C C  G   G+ C+      +E   Q C  G     +L
Sbjct: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYT-GSRCEA---DHNECLSQPCHPGSTCLDLL 494

Query: 121 E------PPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  PP     L +++  ECA+   L  H  C +    F C C  G+S         
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFS----GTRCE 549

Query: 173 XXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                 R   C   G C++ PG++ C C  G+
Sbjct: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGF 581



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 46/191 (24%), Positives = 69/191 (36%), Gaps = 24/191 (12%)

Query: 21   GQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTM 80
            G C+++  SY C CPP ++    G+ C D     C  +   ++G  TC         G +
Sbjct: 905  GLCVDSGPSYFCHCPPGFQ----GSLCQDHVNP-CESR-PCQNGA-TCM----AQPSGYL 953

Query: 81   AACCCSV-GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLA--DIDECAA 137
              C     G       D C       +    P   G+     PP +V      D+DEC  
Sbjct: 954  CQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDECL- 1011

Query: 138  HEGLCAHGT--CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS- 194
             +     GT  C +   +F C C  G +               +P   G G C    GS 
Sbjct: 1012 DQPCHPTGTAACHSLANAFYCQCLPGHT--GQWCEVEIDPCHSQPCFHG-GTCEATAGSP 1068

Query: 195  --YVCLCPEGY 203
              ++C CP+G+
Sbjct: 1069 LGFICHCPKGF 1079



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 20/87 (22%), Positives = 30/87 (34%), Gaps = 6/87 (6%)

Query: 122  PPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
            PP +  +L            C +G TC      ++C C  G+                + 
Sbjct: 919  PPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD----GQNCSKELDACQS 974

Query: 181  DVC-GPGVCRNLPGSYVCLCPEGYVAM 206
              C   G C   PG + C CP G+V +
Sbjct: 975  QPCHNHGTCTPKPGGFHCACPPGFVGL 1001


>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2005

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 61/208 (29%), Positives = 85/208 (40%), Gaps = 32/208 (15%)

Query: 8   DVDEC----KSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           D+DEC    + P  C++G  C+NT GS+ C CPP Y     G+ C ++    C  +    
Sbjct: 434 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRC-EADHNECLSQ-PCH 487

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPGYQP 118
            G+ TC D            C C  G   G  C+     C       +        G+Q 
Sbjct: 488 PGS-TCLDLLATFH------CLCPPGLE-GQLCEVETNECASAPCLNHADCHDLLNGFQC 539

Query: 119 VLEPP-SYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
           +  P  S      DIDEC +    CA+G  C +  G+F C C  G+   P          
Sbjct: 540 ICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFE-GPRCQTEVDECL 596

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
               D C  G  C +LPG++ CLCP G+
Sbjct: 597 S---DPCPVGASCLDLPGAFFCLCPSGF 621



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 55/215 (25%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 1   MPGFN---CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDS---- 50
           MPG+    C   D C +      G C+ T     C CPP +E      D   C+      
Sbjct: 148 MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 207

Query: 51  -RKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
            +   C+    L S    C    E       A  C   G + G  C   PE  S  +  L
Sbjct: 208 PKGTSCHN--TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 265

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXX 168
           CP  PG+   + P   V    + D C +H+  C + GTC +   ++ C C   W+     
Sbjct: 266 CP--PGF---IGPDCEV----NPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGWDCS 314

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      P     G C+N  GS+ C+C  G+
Sbjct: 315 EDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGW 349



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 65/212 (30%), Positives = 88/212 (41%), Gaps = 27/212 (12%)

Query: 3   GFNCT-DVDECKS--PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-G 57
           G++C+ DVDEC++  P  C+ G  C N+ GS+ C C   +   S      D   A C  G
Sbjct: 310 GWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG 369

Query: 58  KVDL-RSGTETCR-DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG 115
              + R G+ +C            +   C S        C   P  GS     LC   PG
Sbjct: 370 STCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST----LCLCQPG 425

Query: 116 YQPVLEPPSYVVTLADIDECA-AHEGL--CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
           Y     P  +     D+DEC  A +G   C HG +C NT GSF C C  G++        
Sbjct: 426 YSG---PTCH----QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--GSRCEA 476

Query: 172 XXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEG 202
                  +P  C PG  C +L  ++ CLCP G
Sbjct: 477 DHNECLSQP--CHPGSTCLDLLATFHCLCPPG 506



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 54/208 (25%), Positives = 72/208 (34%), Gaps = 31/208 (14%)

Query: 1   MPGFNCT----DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           +PGF+ T    D+DEC+S      GQC +  G++ C+C P +E              RC 
Sbjct: 542 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE------------GPRCQ 589

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD-PCPEPGSEAYRQLCPGGPG 115
            +VD    ++ C       +      C C  G   G  C+ P   P     +Q+C     
Sbjct: 590 TEVD-ECLSDPCPVGASCLDLPGAFFCLCPSGFT-GQLCEVPLCAPNLCQPKQICKDQKD 647

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               L P          D C  H G C   +         C C  GW+  P         
Sbjct: 648 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---------CVCDVGWT-GPECEAELGGC 697

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
               P   G G C   P  Y C CP GY
Sbjct: 698 ISA-PCAHG-GTCYPQPSGYNCTCPTGY 723



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 63/218 (28%), Positives = 82/218 (37%), Gaps = 32/218 (14%)

Query: 2   PGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCY 56
           PGF   +C  + D C S Q    G C +   +YTC CP  +     G  C  D  +    
Sbjct: 268 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECEAQ 323

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGP- 114
           G    R+G  TC++S      G+    C S    WG     C E   +     C PG   
Sbjct: 324 GPPHCRNGG-TCQNSA-----GSFHCVCVS---GWGG--TSCEENLDDCIAATCAPGSTC 372

Query: 115 ----GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
               G    L PP     L  +++    +       C TN   GS +C C  G+S  P  
Sbjct: 373 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS-GPTC 431

Query: 169 XXXXXXXXXXR--PDVCGPG-VCRNLPGSYVCLCPEGY 203
                     +  P  C  G  C N PGS+ CLCP GY
Sbjct: 432 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 469



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 46/210 (21%), Positives = 69/210 (32%), Gaps = 28/210 (13%)

Query: 7   TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           T  D C S      G C+N  G+++C C   ++              RC GK+       
Sbjct: 768 TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQ------------GPRCEGKLRPSCADS 815

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWGN---YCDPCPEPGSEAYRQLCPGGPGYQPVL--- 120
            CR+     +      C C  G   G+     D C +            GP +  +    
Sbjct: 816 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQG 875

Query: 121 -EPPSYVVTLADIDECAAHEG-----LCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
              P   + L+   + A  +G     LC + G C ++  S+ C C  G+           
Sbjct: 876 WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHV 933

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                RP   G   C   P  Y+C C  GY
Sbjct: 934 NPCESRPCQNG-ATCMAQPSGYLCQCAPGY 962



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 131 DIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VC 188
           D++EC    G C  GT C NT GSF C C  G    P             P  C  G  C
Sbjct: 196 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GPRCELRAGPCP---PRGCSNGGTC 251

Query: 189 RNLPGS----YVCLCPEGYV 204
           + +P      ++CLCP G++
Sbjct: 252 QLMPEKDSTFHLCLCPPGFI 271



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 52/214 (24%), Positives = 75/214 (35%), Gaps = 27/214 (12%)

Query: 3   GFNCTD-VDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G  C++ +  C S      G C  + G Y C CPP++     G  C  S    C      
Sbjct: 725 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTD-YCVSAPCF 779

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSE----AYRQLCPGGPGYQ 117
             G  TC     ++  GT  +C C++G   G  C+    P         R  C   P   
Sbjct: 780 NGG--TC-----VNRPGTF-SCLCAMGFQ-GPRCEGKLRPSCADSPCRNRATCQDSPQGP 830

Query: 118 PVLEPPSYV-VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS--LAPXXXXXXXX 174
             L P  Y   +   + +  A +    +  C  T  SF C C  GW+  L          
Sbjct: 831 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQK 890

Query: 175 XXXXR----PDVC-GPGVCRNLPGSYVCLCPEGY 203
               +      +C   G+C +   SY C CP G+
Sbjct: 891 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 924



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 51/172 (29%), Positives = 64/172 (37%), Gaps = 23/172 (13%)

Query: 2    PGFN---CTD-VDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
            PGF    C D V+ C+S + CQ G  C+     Y C+C P Y    DG  C     A C 
Sbjct: 922  PGFQGSLCQDHVNPCES-RPCQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDA-CQ 975

Query: 57   GKVDLRSGTETCRDSDE--LSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGP 114
             +     GT T +          G +   C   G        PC   G+ A   L     
Sbjct: 976  SQPCHNHGTCTPKPGGFHCACPPGFVGLRC--EGDVDECLDQPCHPTGTAACHSL--ANA 1031

Query: 115  GYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGS---FVCTCGAGW 162
             Y   L   +      +ID C  H   C H GTC  T GS   F+C C  G+
Sbjct: 1032 FYCQCLPGHTGQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGF 1081



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 51/212 (24%), Positives = 69/212 (32%), Gaps = 28/212 (13%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQ--GSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C   D C S       QC      GS  C C P Y     G  C+      C   + 
Sbjct: 389 GLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLD-EC---LM 440

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
            + G   C              C C  G   G+ C+      +E   Q C  G     +L
Sbjct: 441 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYT-GSRCEA---DHNECLSQPCHPGSTCLDLL 496

Query: 121 E------PPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                  PP     L +++  ECA+   L  H  C +    F C C  G+S         
Sbjct: 497 ATFHCLCPPGLEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFS----GTRCE 551

Query: 173 XXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                 R   C   G C++ PG++ C C  G+
Sbjct: 552 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGF 583



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 46/191 (24%), Positives = 69/191 (36%), Gaps = 24/191 (12%)

Query: 21   GQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTM 80
            G C+++  SY C CPP ++    G+ C D     C  +   ++G  TC         G +
Sbjct: 907  GLCVDSGPSYFCHCPPGFQ----GSLCQDHVNP-CESR-PCQNGA-TCM----AQPSGYL 955

Query: 81   AACCCSV-GAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLA--DIDECAA 137
              C     G       D C       +    P   G+     PP +V      D+DEC  
Sbjct: 956  CQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDECL- 1013

Query: 138  HEGLCAHGT--CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS- 194
             +     GT  C +   +F C C  G +               +P   G G C    GS 
Sbjct: 1014 DQPCHPTGTAACHSLANAFYCQCLPGHT--GQWCEVEIDPCHSQPCFHG-GTCEATAGSP 1070

Query: 195  --YVCLCPEGY 203
              ++C CP+G+
Sbjct: 1071 LGFICHCPKGF 1081



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 20/87 (22%), Positives = 30/87 (34%), Gaps = 6/87 (6%)

Query: 122  PPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
            PP +  +L            C +G TC      ++C C  G+                + 
Sbjct: 921  PPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD----GQNCSKELDACQS 976

Query: 181  DVC-GPGVCRNLPGSYVCLCPEGYVAM 206
              C   G C   PG + C CP G+V +
Sbjct: 977  QPCHNHGTCTPKPGGFHCACPPGFVGL 1003


>AL049651-2|CAB51954.1|  575|Homo sapiens thrombomodulin protein.
          Length = 575

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 56/169 (33%), Positives = 79/169 (46%), Gaps = 27/169 (15%)

Query: 6   CTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR----KARC-YGKV 59
           C DVD+C   P  C   +C+NTQG + C C PNY+LV DG  C +      +A C Y   
Sbjct: 323 CEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLV-DGE-CVEPVDPCFRANCEYQCQ 379

Query: 60  DLRSGTETCRDSD---ELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            L   +  C  ++    +  +       C+  A   + CDP  +   E     CP   GY
Sbjct: 380 PLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-CDPNTQASCE-----CP--EGY 431

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
             +L+   ++ T  DIDEC  + G C+ G C N  G+F C CG   +LA
Sbjct: 432 --ILDD-GFICT--DIDECE-NGGFCS-GVCHNLPGTFECICGPDSALA 473



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/51 (45%), Positives = 29/51 (56%), Gaps = 3/51 (5%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSD-GTACYDSRK 52
           GF CTD+DEC++   C  G C N  G++ C C P+  L    GT C DS K
Sbjct: 436 GFICTDIDECENGGFCS-GVCHNLPGTFECICGPDSALARHIGTDC-DSGK 484



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 3/72 (4%)

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN--L 191
           +C+   G C H  C    G+  C C AG +L                D+C      N   
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302

Query: 192 PGSYVCLCPEGY 203
           PGSY C+C  GY
Sbjct: 303 PGSYSCMCETGY 314



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 50/191 (26%), Positives = 73/191 (38%), Gaps = 24/191 (12%)

Query: 28  GSYTCRCPPNYELVSDGTACYDS-----RKARCYGK-VDLRSGTET-CRDSDELSEDGTM 80
           GSY+C C   Y L +D   C D        + C  + V+ + G E  C  + +L  DG  
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGE- 361

Query: 81  AACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
             C   V   +   C+   +P ++    LC    G+ P+   P       +   C A   
Sbjct: 362 --CVEPVDPCFRANCEYQCQPLNQT-SYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-- 416

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC- 199
            C      NT  S  C C  G+ L                  C  GVC NLPG++ C+C 
Sbjct: 417 -CD----PNTQAS--CECPEGYIL-DDGFICTDIDECENGGFCS-GVCHNLPGTFECICG 467

Query: 200 PEGYVAMPNGS 210
           P+  +A   G+
Sbjct: 468 PDSALARHIGT 478



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 35/139 (25%), Positives = 43/139 (30%), Gaps = 15/139 (10%)

Query: 78  GTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADI 132
           G    C    GA  G++    P        +      C   PG  P  + P+     AD 
Sbjct: 219 GLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPG-APRCQCPAGAALQADG 277

Query: 133 DECAAH-----EGLCAHGTCTNTF--GSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCG 184
             C A        LC H    N    GS+ C C  G+ LA               P  C 
Sbjct: 278 RSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC- 336

Query: 185 PGVCRNLPGSYVCLCPEGY 203
           P  C N  G + C C   Y
Sbjct: 337 PQRCVNTQGGFECHCYPNY 355


>AK075214-1|BAC11477.1|  553|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90733 fis, clone PLACE1010251, highly similar to
           Epidermal growth factor-like protein 6 precursor. ).
          Length = 553

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 54/171 (31%), Positives = 71/171 (41%), Gaps = 18/171 (10%)

Query: 3   GFNCT-DVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA---RC-Y 56
           G  C+ DV+EC   P+ CQ+ +C+NT GSY C C   + L+ D T C +SR      C Y
Sbjct: 88  GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDAT-CVNSRTCAMINCQY 145

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
              D   G +    S  L        C     C+ G     Y   C       Y   C  
Sbjct: 146 SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYY---CKC 202

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGW 162
             G++  L+  S      DI+EC      C+ H  C NT GSF C C  G+
Sbjct: 203 HIGFE--LQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 58/208 (27%), Positives = 77/208 (37%), Gaps = 21/208 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDSRKARCYGKVDL 61
           N   V E      C++G+C+   G   CRC P Y       D   C    +   +  V+ 
Sbjct: 56  NSKGVCEATCEPGCKFGECV---GPNKCRCFPGYTGKTCSQDVNECGMKPRPCQHRCVNT 112

Query: 62  RSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
               +  C     L  D T   C  S   A  N C    E   E  + LCP   G +  L
Sbjct: 113 HGSYKCFCLSGHMLMPDAT---CVNSRTCAMIN-CQYSCEDTEEGPQCLCPSS-GLR--L 165

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSL---APXXXXXXXXXX 176
            P        DIDECA+ + +C +   C NTFGS+ C C  G+ L   +           
Sbjct: 166 APNGR--DCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC 223

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
                 C     C N  GS+ C C +GY
Sbjct: 224 TMDSHTCSHHANCFNTQGSFKCKCKQGY 251



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 36/137 (26%), Positives = 46/137 (33%), Gaps = 8/137 (5%)

Query: 78  GTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
           GT  ACC          C+   EPG +    +   GP         +      D++EC  
Sbjct: 44  GTKLACCYGWRRNSKGVCEATCEPGCKFGECV---GPNKCRCFPGYTGKTCSQDVNECGM 100

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVC 197
               C H  C NT GS+ C C +G  L P               +     C +      C
Sbjct: 101 KPRPCQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAM---INCQYSCEDTEEGPQC 156

Query: 198 LCP-EGYVAMPNGSQYL 213
           LCP  G    PNG   L
Sbjct: 157 LCPSSGLRLAPNGRDCL 173



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 4/46 (8%)

Query: 4   FNCTDVDECK-SPQSCQY-GQCINTQGSYTCRCPPNYELVSDGTAC 47
           ++C D++EC     +C +   C NTQGS+ C+C   Y+   +G  C
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK--GNGLRC 258


>AJ245671-1|CAB92132.1|  554|Homo sapiens hypothetical protein
           protein.
          Length = 554

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 54/171 (31%), Positives = 71/171 (41%), Gaps = 18/171 (10%)

Query: 3   GFNCT-DVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA---RC-Y 56
           G  C+ DV+EC   P+ CQ+ +C+NT GSY C C   + L+ D T C +SR      C Y
Sbjct: 88  GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDAT-CVNSRTCAMINCQY 145

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
              D   G +    S  L        C     C+ G     Y   C       Y   C  
Sbjct: 146 SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYY---CKC 202

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGW 162
             G++  L+  S      DI+EC      C+ H  C NT GSF C C  G+
Sbjct: 203 HIGFE--LQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 58/208 (27%), Positives = 77/208 (37%), Gaps = 21/208 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDSRKARCYGKVDL 61
           N   V E      C++G+C+   G   CRC P Y       D   C    +   +  V+ 
Sbjct: 56  NSKGVCEATCEPGCKFGECV---GPNKCRCFPGYTGKTCSQDVNECGMKPRPCQHRCVNT 112

Query: 62  RSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
               +  C     L  D T   C  S   A  N C    E   E  + LCP   G +  L
Sbjct: 113 HGSYKCFCLSGHMLMPDAT---CVNSRTCAMIN-CQYSCEDTEEGPQCLCPSS-GLR--L 165

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSL---APXXXXXXXXXX 176
            P        DIDECA+ + +C +   C NTFGS+ C C  G+ L   +           
Sbjct: 166 APNGR--DCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC 223

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
                 C     C N  GS+ C C +GY
Sbjct: 224 TMDSHTCSHHANCFNTQGSFKCKCKQGY 251



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 36/137 (26%), Positives = 46/137 (33%), Gaps = 8/137 (5%)

Query: 78  GTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
           GT  ACC          C+   EPG +    +   GP         +      D++EC  
Sbjct: 44  GTKLACCYGWRRNSKGVCEATCEPGCKFGECV---GPNKCRCFPGYTGKTCSQDVNECGM 100

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVC 197
               C H  C NT GS+ C C +G  L P               +     C +      C
Sbjct: 101 KPRPCQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAM---INCQYSCEDTEEGPQC 156

Query: 198 LCP-EGYVAMPNGSQYL 213
           LCP  G    PNG   L
Sbjct: 157 LCPSSGLRLAPNGRDCL 173



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 4/46 (8%)

Query: 4   FNCTDVDECK-SPQSCQY-GQCINTQGSYTCRCPPNYELVSDGTAC 47
           ++C D++EC     +C +   C NTQGS+ C+C   Y+   +G  C
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK--GNGLRC 258


>AF495471-1|AAM03232.1|  575|Homo sapiens thrombomodulin protein.
          Length = 575

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 56/169 (33%), Positives = 79/169 (46%), Gaps = 27/169 (15%)

Query: 6   CTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR----KARC-YGKV 59
           C DVD+C   P  C   +C+NTQG + C C PNY+LV DG  C +      +A C Y   
Sbjct: 323 CEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLV-DGE-CVEPVDPCFRANCEYQCQ 379

Query: 60  DLRSGTETCRDSD---ELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            L   +  C  ++    +  +       C+  A   + CDP  +   E     CP   GY
Sbjct: 380 PLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-CDPNTQASCE-----CP--EGY 431

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
             +L+   ++ T  DIDEC  + G C+ G C N  G+F C CG   +LA
Sbjct: 432 --ILDD-GFICT--DIDECE-NGGFCS-GVCHNLPGTFECICGPDSALA 473



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/51 (45%), Positives = 29/51 (56%), Gaps = 3/51 (5%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSD-GTACYDSRK 52
           GF CTD+DEC++   C  G C N  G++ C C P+  L    GT C DS K
Sbjct: 436 GFICTDIDECENGGFCS-GVCHNLPGTFECICGPDSALARHIGTDC-DSGK 484



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 3/72 (4%)

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN--L 191
           +C+   G C H  C    G+  C C AG +L                D+C      N   
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302

Query: 192 PGSYVCLCPEGY 203
           PGSY C+C  GY
Sbjct: 303 PGSYSCMCETGY 314



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 50/191 (26%), Positives = 73/191 (38%), Gaps = 24/191 (12%)

Query: 28  GSYTCRCPPNYELVSDGTACYDS-----RKARCYGK-VDLRSGTET-CRDSDELSEDGTM 80
           GSY+C C   Y L +D   C D        + C  + V+ + G E  C  + +L  DG  
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGE- 361

Query: 81  AACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
             C   V   +   C+   +P ++    LC    G+ P+   P       +   C A   
Sbjct: 362 --CVEPVDPCFRANCEYQCQPLNQT-SYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-- 416

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC- 199
            C      NT  S  C C  G+ L                  C  GVC NLPG++ C+C 
Sbjct: 417 -CD----PNTQAS--CECPEGYIL-DDGFICTDIDECENGGFCS-GVCHNLPGTFECICG 467

Query: 200 PEGYVAMPNGS 210
           P+  +A   G+
Sbjct: 468 PDSALARHIGT 478



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 35/139 (25%), Positives = 43/139 (30%), Gaps = 15/139 (10%)

Query: 78  GTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADI 132
           G    C    GA  G++    P        +      C   PG  P  + P+     AD 
Sbjct: 219 GLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPG-APRCQCPAGAALQADG 277

Query: 133 DECAAH-----EGLCAHGTCTNTF--GSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCG 184
             C A        LC H    N    GS+ C C  G+ LA               P  C 
Sbjct: 278 RSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC- 336

Query: 185 PGVCRNLPGSYVCLCPEGY 203
           P  C N  G + C C   Y
Sbjct: 337 PQRCVNTQGGFECHCYPNY 355


>AF186084-1|AAF27812.1|  553|Homo sapiens epidermal growth factor
           repeat containing protein protein.
          Length = 553

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 54/171 (31%), Positives = 71/171 (41%), Gaps = 18/171 (10%)

Query: 3   GFNCT-DVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA---RC-Y 56
           G  C+ DV+EC   P+ CQ+ +C+NT GSY C C   + L+ D T C +SR      C Y
Sbjct: 88  GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDAT-CVNSRTCAMINCQY 145

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
              D   G +    S  L        C     C+ G     Y   C       Y   C  
Sbjct: 146 SCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYY---CKC 202

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGW 162
             G++  L+  S      DI+EC      C+ H  C NT GSF C C  G+
Sbjct: 203 HIGFE--LQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 58/208 (27%), Positives = 77/208 (37%), Gaps = 21/208 (10%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDSRKARCYGKVDL 61
           N   V E      C++G+C+   G   CRC P Y       D   C    +   +  V+ 
Sbjct: 56  NSKGVCEATCEPGCKFGECV---GPNKCRCFPGYTGKTCSQDVNECGMKPRPCQHRCVNT 112

Query: 62  RSGTET-CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
               +  C     L  D T   C  S   A  N C    E   E  + LCP   G +  L
Sbjct: 113 HGSYKCFCLSGHMLMPDAT---CVNSRTCAMIN-CQYSCEDTEEGPQCLCPSS-GLR--L 165

Query: 121 EPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSL---APXXXXXXXXXX 176
            P        DIDECA+ + +C +   C NTFGS+ C C  G+ L   +           
Sbjct: 166 APNGR--DCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC 223

Query: 177 XXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
                 C     C N  GS+ C C +GY
Sbjct: 224 TMDSHTCSHHANCFNTQGSFKCKCKQGY 251



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 36/137 (26%), Positives = 46/137 (33%), Gaps = 8/137 (5%)

Query: 78  GTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAA 137
           GT  ACC          C+   EPG +    +   GP         +      D++EC  
Sbjct: 44  GTKLACCYGWRRNSKGVCEATCEPGCKFGECV---GPNKCRCFPGYTGKTCSQDVNECGM 100

Query: 138 HEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVC 197
               C H  C NT GS+ C C +G  L P               +     C +      C
Sbjct: 101 KPRPCQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAM---INCQYSCEDTEEGPQC 156

Query: 198 LCP-EGYVAMPNGSQYL 213
           LCP  G    PNG   L
Sbjct: 157 LCPSSGLRLAPNGRDCL 173



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 4/46 (8%)

Query: 4   FNCTDVDECK-SPQSCQY-GQCINTQGSYTCRCPPNYELVSDGTAC 47
           ++C D++EC     +C +   C NTQGS+ C+C   Y+   +G  C
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK--GNGLRC 258


>AF093118-1|AAC62107.1|  448|Homo sapiens UP50 protein.
          Length = 448

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 7/105 (6%)

Query: 107 RQLCPGGPGYQPVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAG 161
           +QLC   PG       P + +     +  D++ECA  E  C   TC NT+GSF+C C  G
Sbjct: 178 QQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQ-TCVNTYGSFICRCDPG 235

Query: 162 WSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAM 206
           + L                +      C N PG+Y C CP GY+ +
Sbjct: 236 YELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILL 280



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 23/47 (48%), Positives = 28/47 (59%), Gaps = 1/47 (2%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C DV+EC +   C    C+NT GS+ CRC P YEL  DG  C D
Sbjct: 202 GRSCQDVNECATENPCVQ-TCVNTYGSFICRCDPGYELEEDGVHCSD 247



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 51/160 (31%), Positives = 67/160 (41%), Gaps = 20/160 (12%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR----CYGKVDL 61
           C D+DEC+    CQ   C N  GSY+C C P + L  DG +C D  +      C      
Sbjct: 166 CLDIDECRYGY-CQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVN 223

Query: 62  RSGTETCR--DSDELSEDGTMAACC--CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
             G+  CR     EL EDG   +    CS       + +   +PG+  Y   CP  PGY 
Sbjct: 224 TYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGT--YFCSCP--PGY- 277

Query: 118 PVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVC 156
            +L   +   +  DI+EC      C    TC N  G F C
Sbjct: 278 -ILLDDNR--SCQDINECEHRNHTCNLQQTCYNLQGGFKC 314



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 22/48 (45%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 3   GFNCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G +C+D+DEC  S   CQ+ +C+N  G+Y C CPP Y L+ D  +C D
Sbjct: 242 GVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQD 288



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 48/199 (24%), Positives = 74/199 (37%), Gaps = 24/199 (12%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR-DSDELSEDGTMA 81
           C+ + G+   +C   ++L        D +  +C    + R+  E CR D   ++++G   
Sbjct: 16  CLPSPGNAQAQCTNGFDL--------DRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYL 67

Query: 82  ACCCSVGAAWGNYCDPCPEPGSEAYRQLCP--GGPGYQPVLEPP----SYVVT----LAD 131
               +     G Y +P   P S  Y    P    P Y  +  P      Y +       D
Sbjct: 68  CHSRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVD 127

Query: 132 IDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           +DECA     C     C N  G + C+C  G+ L              R   C   +C N
Sbjct: 128 VDECATDSHQCNPTQICINMKGGYTCSCTDGYWLLEGQCLDIDEC---RYGYCQQ-LCAN 183

Query: 191 LPGSYVCLCPEGYVAMPNG 209
           +PGSY C C  G+    +G
Sbjct: 184 VPGSYSCTCNPGFTLNEDG 202



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 52/214 (24%), Positives = 79/214 (36%), Gaps = 21/214 (9%)

Query: 6   CTDVDECKS-PQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-GKVDLR 62
           C D+DEC++ P++C+    C+N  G Y   C      V  G   Y +  +  Y G     
Sbjct: 40  CLDIDECRTIPEACRGDMMCVNQNGGYL--CHSRTNPVYRGP--YSNPYSTPYSGPYPAA 95

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYR----QLCPGGPGYQP 118
           +   +  +   +S       C         N C    E  +++++    Q+C    G   
Sbjct: 96  APPLSAPNYPTISRP---LICRFGYQMDESNQCVDVDECATDSHQCNPTQICINMKGGYT 152

Query: 119 VLEPPSYVVT---LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                 Y +      DIDEC    G C    C N  GS+ CTC  G++L           
Sbjct: 153 CSCTDGYWLLEGQCLDIDEC--RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVN 209

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                + C    C N  GS++C C  GY    +G
Sbjct: 210 ECATENPCVQ-TCVNTYGSFICRCDPGYELEEDG 242


>U69263-1|AAC51260.2|  956|Homo sapiens matrilin-2 precursor
           protein.
          Length = 956

 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 57/194 (29%), Positives = 70/194 (36%), Gaps = 15/194 (7%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACYDS-----RKARCYGKVDLRSGTETCR--DSDELS 75
           CIN  GSY CRC   Y L SD T C            C        G+  C+      L+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312

Query: 76  EDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDEC 135
           EDG          A+  + C+        +Y  LC    G+   L P     T   ID C
Sbjct: 313 EDGKRCVAV-DYCASENHGCEHECVNADGSY--LCQCHEGF--ALNPDKKTCT--KIDYC 365

Query: 136 AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSY 195
           A+    C H  C NT  S+ C C  G++L P                     C N+  SY
Sbjct: 366 ASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESY 424

Query: 196 VCLCPEGYVAMPNG 209
            C C  GY   PNG
Sbjct: 425 YCRCHRGYTLDPNG 438



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 61/224 (27%), Positives = 83/224 (37%), Gaps = 35/224 (15%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD- 60
           G  C  VD C S    C++ +C+N  GSY C+C   + L  D   C          K+D 
Sbjct: 315 GKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTC---------TKIDY 364

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWG---------NYCDPCPEPGSE------A 105
             S    C+     ++D    +C C  G             NYC    +PG E       
Sbjct: 365 CASSNHGCQHECVNTDDS--YSCHCLKGFTLNPDKKTCRRINYC-ALNKPGCEHECVNME 421

Query: 106 YRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
               C    GY   L+P     T + +D CA  +  C    C NT  SFVC C  G+ + 
Sbjct: 422 ESYYCRCHRGY--TLDPNG--KTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLIN 476

Query: 166 PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                          D      C N+  S+ C CPEG+V   +G
Sbjct: 477 EDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDG 520



 Score = 57.2 bits (132), Expect = 4e-08
 Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 23/218 (10%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
           G  C+ VD C +    C+   C+NT+ S+ C+C   + +  D   C  SR   C      
Sbjct: 438 GKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTC--SRVDYCLLSDHG 494

Query: 56  --YGKVDL-RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCP 111
             Y  V++ RS    C +   L  DG    C      A G++ C+       +++  +C 
Sbjct: 495 CEYSCVNMDRSFACQCPEGHVLRSDG--KTCAKLDSCALGDHGCEHSCVSSEDSF--VCQ 550

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXX 171
              GY  +L          D+  C A +  C H  C N+  S+ C C  G+ LA      
Sbjct: 551 CFEGY--ILREDGKTCRRKDV--CQAIDHGCEH-ICVNSDDSYTCECLVGFRLAEDGKRC 605

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                          +C N   SY+C C EG+V   +G
Sbjct: 606 RRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDG 643



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 54/215 (25%), Positives = 83/215 (38%), Gaps = 19/215 (8%)

Query: 6   CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC----YGKVD 60
           C  ++ C  +   C++ +C+N + SY CRC   Y L  +G  C  SR   C    +G   
Sbjct: 400 CRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTC--SRVDHCAQQDHGCEQ 456

Query: 61  LRSGTE---TCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGY 116
           L   TE    C+ S+    +  +  C         ++ C+        ++   CP G   
Sbjct: 457 LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGH-- 514

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
             VL       T A +D CA  +  C H +C ++  SFVC C  G+ L            
Sbjct: 515 --VLRSDGK--TCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDV 569

Query: 177 XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
               D     +C N   SY C C  G+    +G +
Sbjct: 570 CQAIDHGCEHICVNSDDSYTCECLVGFRLAEDGKR 604



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 15/211 (7%)

Query: 6   CTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTAC----YDS-RKARCYGKV 59
           CT +D C S    CQ+ +C+NT  SY+C C   + L  D   C    Y +  K  C  + 
Sbjct: 359 CTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHEC 417

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGYQP 118
                +  CR     + D     C      A  ++ C+       +++  +C    G+  
Sbjct: 418 VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSF--VCQCSEGFL- 474

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           + E    + T + +D C   +  C + +C N   SF C C  G  L              
Sbjct: 475 INED---LKTCSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCA 530

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
             D      C +   S+VC C EGY+   +G
Sbjct: 531 LGDHGCEHSCVSSEDSFVCQCFEGYILREDG 561



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS 194
           C+  E  CAH  C N  GS+VC C  G+ L                D     +C N+PGS
Sbjct: 242 CSTLEHNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGS 300

Query: 195 YVCLCPEGYVAMPNGSQ 211
           +VC C  GY    +G +
Sbjct: 301 FVCQCYSGYALAEDGKR 317



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 9/90 (10%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC--YDSRKARCYG-- 57
           G  C   D C++    C++  C+N+  SYTC C   + L  DG  C   D  K+  +G  
Sbjct: 561 GKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLVGFRLAEDGKRCRRKDVCKSTHHGCE 619

Query: 58  KVDLRSGTE---TCRDSDELSEDGTMAACC 84
            + + +G      C +   L+EDG     C
Sbjct: 620 HICVNNGNSYICKCSEGFVLAEDGRRCKKC 649



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/30 (43%), Positives = 20/30 (66%)

Query: 188 CRNLPGSYVCLCPEGYVAMPNGSQYLLQNL 217
           C N+PGSYVC C +GY+   + +   +Q+L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDL 282


>BC016394-1|AAH16394.1|  715|Homo sapiens MATN2 protein protein.
          Length = 715

 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 57/194 (29%), Positives = 70/194 (36%), Gaps = 15/194 (7%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACYDS-----RKARCYGKVDLRSGTETCR--DSDELS 75
           CIN  GSY CRC   Y L SD T C            C        G+  C+      L+
Sbjct: 12  CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 71

Query: 76  EDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDEC 135
           EDG          A+  + C+        +Y  LC    G+   L P     T   ID C
Sbjct: 72  EDGKRCVAV-DYCASENHGCEHECVNADGSY--LCQCHEGF--ALNPDEKTCT--KIDYC 124

Query: 136 AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSY 195
           A+    C H  C NT  S+ C C  G++L P                     C N+  SY
Sbjct: 125 ASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESY 183

Query: 196 VCLCPEGYVAMPNG 209
            C C  GY   PNG
Sbjct: 184 YCRCHRGYTLDPNG 197



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 61/224 (27%), Positives = 83/224 (37%), Gaps = 35/224 (15%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD- 60
           G  C  VD C S    C++ +C+N  GSY C+C   + L  D   C          K+D 
Sbjct: 74  GKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTC---------TKIDY 123

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWG---------NYCDPCPEPGSE------A 105
             S    C+     ++D    +C C  G             NYC    +PG E       
Sbjct: 124 CASSNHGCQHECVNTDDS--YSCHCLKGFTLNPDKKTCRRINYC-ALNKPGCEHECVNME 180

Query: 106 YRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
               C    GY   L+P     T + +D CA  +  C    C NT  SFVC C  G+ + 
Sbjct: 181 ESYYCRCHRGY--TLDPNG--KTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLIN 235

Query: 166 PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                          D      C N+  S+ C CPEG+V   +G
Sbjct: 236 EDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDG 279



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 23/218 (10%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
           G  C+ VD C +    C+   C+NT+ S+ C+C   + +  D   C  SR   C      
Sbjct: 197 GKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTC--SRVDYCLLSDHG 253

Query: 56  --YGKVDL-RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCP 111
             Y  V++ RS    C +   L  DG    C      A G++ C+       +++  +C 
Sbjct: 254 CEYSCVNMDRSFACQCPEGHVLRSDG--KTCAKLDSCALGDHGCEHSCVSSEDSF--VCQ 309

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXX 171
              GY  +L          D+  C A +  C H  C N+  S+ C C  G+ LA      
Sbjct: 310 CFEGY--ILREDGKTCRRKDV--CQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRC 364

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                          +C N   SY+C C EG+V   +G
Sbjct: 365 RRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDG 402



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 55/215 (25%), Positives = 84/215 (39%), Gaps = 19/215 (8%)

Query: 6   CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC----YGKVD 60
           C  ++ C  +   C++ +C+N + SY CRC   Y L  +G  C  SR   C    +G   
Sbjct: 159 CRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTC--SRVDHCAQQDHGCEQ 215

Query: 61  LRSGTE---TCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGY 116
           L   TE    C+ S+    +  +  C         ++ C+        ++   CP G   
Sbjct: 216 LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGH-- 273

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
             VL       T A +D CA  +  C H +C ++  SFVC C  G+ L            
Sbjct: 274 --VLRSDGK--TCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDV 328

Query: 177 XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
               D     +C N   SY C C EG+    +G +
Sbjct: 329 CQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKR 363



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 15/211 (7%)

Query: 6   CTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTAC----YDS-RKARCYGKV 59
           CT +D C S    CQ+ +C+NT  SY+C C   + L  D   C    Y +  K  C  + 
Sbjct: 118 CTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHEC 176

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGYQP 118
                +  CR     + D     C      A  ++ C+       +++  +C    G+  
Sbjct: 177 VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSF--VCQCSEGFL- 233

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           + E    + T + +D C   +  C + +C N   SF C C  G  L              
Sbjct: 234 INED---LKTCSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCA 289

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
             D      C +   S+VC C EGY+   +G
Sbjct: 290 LGDHGCEHSCVSSEDSFVCQCFEGYILREDG 320



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS 194
           C+  E  CAH  C N  GS+VC C  G+ L                D     +C N+PGS
Sbjct: 1   CSTLEHNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGS 59

Query: 195 YVCLCPEGYVAMPNGSQ 211
           +VC C  GY    +G +
Sbjct: 60  FVCQCYSGYALAEDGKR 76



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 9/90 (10%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC--YDSRKARCYG-- 57
           G  C   D C++    C++  C+N+  SYTC C   + L  DG  C   D  K+  +G  
Sbjct: 320 GKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCE 378

Query: 58  KVDLRSGTE---TCRDSDELSEDGTMAACC 84
            + + +G      C +   L+EDG     C
Sbjct: 379 HICVNNGNSYICKCSEGFVLAEDGRRCKKC 408



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/30 (43%), Positives = 20/30 (66%)

Query: 188 CRNLPGSYVCLCPEGYVAMPNGSQYLLQNL 217
           C N+PGSYVC C +GY+   + +   +Q+L
Sbjct: 12  CINIPGSYVCRCKQGYILNSDQTTCRIQDL 41


>BC010444-1|AAH10444.1|  937|Homo sapiens matrilin 2 protein.
          Length = 937

 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 57/194 (29%), Positives = 70/194 (36%), Gaps = 15/194 (7%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACYDS-----RKARCYGKVDLRSGTETCR--DSDELS 75
           CIN  GSY CRC   Y L SD T C            C        G+  C+      L+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312

Query: 76  EDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDEC 135
           EDG          A+  + C+        +Y  LC    G+   L P     T   ID C
Sbjct: 313 EDGKRCVAV-DYCASENHGCEHECVNADGSY--LCQCHEGF--ALNPDEKTCT--KIDYC 365

Query: 136 AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSY 195
           A+    C H  C NT  S+ C C  G++L P                     C N+  SY
Sbjct: 366 ASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESY 424

Query: 196 VCLCPEGYVAMPNG 209
            C C  GY   PNG
Sbjct: 425 YCRCHRGYTLDPNG 438



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 61/224 (27%), Positives = 83/224 (37%), Gaps = 35/224 (15%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD- 60
           G  C  VD C S    C++ +C+N  GSY C+C   + L  D   C          K+D 
Sbjct: 315 GKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTC---------TKIDY 364

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWG---------NYCDPCPEPGSE------A 105
             S    C+     ++D    +C C  G             NYC    +PG E       
Sbjct: 365 CASSNHGCQHECVNTDDS--YSCHCLKGFTLNPDKKTCRRINYC-ALNKPGCEHECVNME 421

Query: 106 YRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
               C    GY   L+P     T + +D CA  +  C    C NT  SFVC C  G+ + 
Sbjct: 422 ESYYCRCHRGY--TLDPNG--KTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLIN 476

Query: 166 PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                          D      C N+  S+ C CPEG+V   +G
Sbjct: 477 EDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDG 520



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 23/218 (10%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
           G  C+ VD C +    C+   C+NT+ S+ C+C   + +  D   C  SR   C      
Sbjct: 438 GKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTC--SRVDYCLLSDHG 494

Query: 56  --YGKVDL-RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCP 111
             Y  V++ RS    C +   L  DG    C      A G++ C+       +++  +C 
Sbjct: 495 CEYSCVNMDRSFACQCPEGHVLRSDG--KTCAKLDSCALGDHGCEHSCVSSEDSF--VCQ 550

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXX 171
              GY  +L          D+  C A +  C H  C N+  S+ C C  G+ LA      
Sbjct: 551 CFEGY--ILREDGKTCRRKDV--CQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRC 605

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                          +C N   SY+C C EG+V   +G
Sbjct: 606 RRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDG 643



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 55/215 (25%), Positives = 84/215 (39%), Gaps = 19/215 (8%)

Query: 6   CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC----YGKVD 60
           C  ++ C  +   C++ +C+N + SY CRC   Y L  +G  C  SR   C    +G   
Sbjct: 400 CRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTC--SRVDHCAQQDHGCEQ 456

Query: 61  LRSGTE---TCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGY 116
           L   TE    C+ S+    +  +  C         ++ C+        ++   CP G   
Sbjct: 457 LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGH-- 514

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
             VL       T A +D CA  +  C H +C ++  SFVC C  G+ L            
Sbjct: 515 --VLRSDGK--TCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDV 569

Query: 177 XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
               D     +C N   SY C C EG+    +G +
Sbjct: 570 CQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKR 604



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 15/211 (7%)

Query: 6   CTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTAC----YDS-RKARCYGKV 59
           CT +D C S    CQ+ +C+NT  SY+C C   + L  D   C    Y +  K  C  + 
Sbjct: 359 CTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHEC 417

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGYQP 118
                +  CR     + D     C      A  ++ C+       +++  +C    G+  
Sbjct: 418 VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSF--VCQCSEGFL- 474

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           + E    + T + +D C   +  C + +C N   SF C C  G  L              
Sbjct: 475 INED---LKTCSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCA 530

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
             D      C +   S+VC C EGY+   +G
Sbjct: 531 LGDHGCEHSCVSSEDSFVCQCFEGYILREDG 561



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS 194
           C+  E  CAH  C N  GS+VC C  G+ L                D     +C N+PGS
Sbjct: 242 CSTLEHNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGS 300

Query: 195 YVCLCPEGYVAMPNGSQ 211
           +VC C  GY    +G +
Sbjct: 301 FVCQCYSGYALAEDGKR 317



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 9/90 (10%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC--YDSRKARCYG-- 57
           G  C   D C++    C++  C+N+  SYTC C   + L  DG  C   D  K+  +G  
Sbjct: 561 GKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCE 619

Query: 58  KVDLRSGTE---TCRDSDELSEDGTMAACC 84
            + + +G      C +   L+EDG     C
Sbjct: 620 HICVNNGNSYICKCSEGFVLAEDGRRCKKC 649



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/30 (43%), Positives = 20/30 (66%)

Query: 188 CRNLPGSYVCLCPEGYVAMPNGSQYLLQNL 217
           C N+PGSYVC C +GY+   + +   +Q+L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDL 282


>AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein
           protein.
          Length = 1016

 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 57/194 (29%), Positives = 70/194 (36%), Gaps = 15/194 (7%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACYDS-----RKARCYGKVDLRSGTETCR--DSDELS 75
           CIN  GSY CRC   Y L SD T C            C        G+  C+      L+
Sbjct: 313 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 372

Query: 76  EDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDEC 135
           EDG          A+  + C+        +Y  LC    G+   L P     T   ID C
Sbjct: 373 EDGKRCVAV-DYCASENHGCEHECVNADGSY--LCQCHEGF--ALNPDEKTCT--KIDYC 425

Query: 136 AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSY 195
           A+    C H  C NT  S+ C C  G++L P                     C N+  SY
Sbjct: 426 ASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESY 484

Query: 196 VCLCPEGYVAMPNG 209
            C C  GY   PNG
Sbjct: 485 YCRCHRGYTLDPNG 498



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 61/224 (27%), Positives = 83/224 (37%), Gaps = 35/224 (15%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD- 60
           G  C  VD C S    C++ +C+N  GSY C+C   + L  D   C          K+D 
Sbjct: 375 GKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTC---------TKIDY 424

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWG---------NYCDPCPEPGSE------A 105
             S    C+     ++D    +C C  G             NYC    +PG E       
Sbjct: 425 CASSNHGCQHECVNTDDS--YSCHCLKGFTLNPDKKTCRRINYC-ALNKPGCEHECVNME 481

Query: 106 YRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
               C    GY   L+P     T + +D CA  +  C    C NT  SFVC C  G+ + 
Sbjct: 482 ESYYCRCHRGY--TLDPNG--KTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLIN 536

Query: 166 PXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                          D      C N+  S+ C CPEG+V   +G
Sbjct: 537 EDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDG 580



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 23/218 (10%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
           G  C+ VD C +    C+   C+NT+ S+ C+C   + +  D   C  SR   C      
Sbjct: 498 GKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTC--SRVDYCLLSDHG 554

Query: 56  --YGKVDL-RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCP 111
             Y  V++ RS    C +   L  DG    C      A G++ C+       +++  +C 
Sbjct: 555 CEYSCVNMDRSFACQCPEGHVLRSDG--KTCAKLDSCALGDHGCEHSCVSSEDSF--VCQ 610

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXX 171
              GY  +L          D+  C A +  C H  C N+  S+ C C  G+ LA      
Sbjct: 611 CFEGY--ILREDGKTCRRKDV--CQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRC 665

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                          +C N   SY+C C EG+V   +G
Sbjct: 666 RRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDG 703



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 55/215 (25%), Positives = 84/215 (39%), Gaps = 19/215 (8%)

Query: 6   CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC----YGKVD 60
           C  ++ C  +   C++ +C+N + SY CRC   Y L  +G  C  SR   C    +G   
Sbjct: 460 CRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTC--SRVDHCAQQDHGCEQ 516

Query: 61  LRSGTE---TCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGY 116
           L   TE    C+ S+    +  +  C         ++ C+        ++   CP G   
Sbjct: 517 LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGH-- 574

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
             VL       T A +D CA  +  C H +C ++  SFVC C  G+ L            
Sbjct: 575 --VLRSDGK--TCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDV 629

Query: 177 XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
               D     +C N   SY C C EG+    +G +
Sbjct: 630 CQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKR 664



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 15/211 (7%)

Query: 6   CTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTAC----YDS-RKARCYGKV 59
           CT +D C S    CQ+ +C+NT  SY+C C   + L  D   C    Y +  K  C  + 
Sbjct: 419 CTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHEC 477

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGYQP 118
                +  CR     + D     C      A  ++ C+       +++  +C    G+  
Sbjct: 478 VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSF--VCQCSEGFL- 534

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           + E    + T + +D C   +  C + +C N   SF C C  G  L              
Sbjct: 535 INED---LKTCSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCA 590

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
             D      C +   S+VC C EGY+   +G
Sbjct: 591 LGDHGCEHSCVSSEDSFVCQCFEGYILREDG 621



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS 194
           C+  E  CAH  C N  GS+VC C  G+ L                D     +C N+PGS
Sbjct: 302 CSTLEHNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGS 360

Query: 195 YVCLCPEGYVAMPNGSQ 211
           +VC C  GY    +G +
Sbjct: 361 FVCQCYSGYALAEDGKR 377



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 9/90 (10%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC--YDSRKARCYG-- 57
           G  C   D C++    C++  C+N+  SYTC C   + L  DG  C   D  K+  +G  
Sbjct: 621 GKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCE 679

Query: 58  KVDLRSGTE---TCRDSDELSEDGTMAACC 84
            + + +G      C +   L+EDG     C
Sbjct: 680 HICVNNGNSYICKCSEGFVLAEDGRRCKKC 709



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/30 (43%), Positives = 20/30 (66%)

Query: 188 CRNLPGSYVCLCPEGYVAMPNGSQYLLQNL 217
           C N+PGSYVC C +GY+   + +   +Q+L
Sbjct: 313 CINIPGSYVCRCKQGYILNSDQTTCRIQDL 342


>AK075489-1|BAC11648.1|  451|Homo sapiens rase 7.  protein.
          Length = 451

 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 57/194 (29%), Positives = 70/194 (36%), Gaps = 15/194 (7%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACYDS-----RKARCYGKVDLRSGTETCR--DSDELS 75
           CIN  GSY CRC   Y L SD T C            C        G+  C+      L+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312

Query: 76  EDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDEC 135
           EDG          A+  + C+        +Y  LC    G+   L P     T   ID C
Sbjct: 313 EDGKRCVAV-DYCASENHGCEHECVNADGSY--LCQCHEGF--ALNPDKKTCT--KIDYC 365

Query: 136 AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSY 195
           A+    C H  C NT  S+ C C  G++L P                     C N+  SY
Sbjct: 366 ASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESY 424

Query: 196 VCLCPEGYVAMPNG 209
            C C  GY   PNG
Sbjct: 425 YCRCHRGYTLDPNG 438



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS 194
           C+  E  CAH  C N  GS+VC C  G+ L                D     +C N+PGS
Sbjct: 242 CSTLEHNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGS 300

Query: 195 YVCLCPEGYVAMPNGSQ 211
           +VC C  GY    +G +
Sbjct: 301 FVCQCYSGYALAEDGKR 317



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%)

Query: 6   CTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           CT +D C S    CQ+ +C+NT  SY+C C   + L  D   C
Sbjct: 359 CTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTC 400



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 2/46 (4%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G  C  VD C S    C++ +C+N  GSY C+C   + L  D   C
Sbjct: 315 GKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTC 359



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/30 (43%), Positives = 20/30 (66%)

Query: 188 CRNLPGSYVCLCPEGYVAMPNGSQYLLQNL 217
           C N+PGSYVC C +GY+   + +   +Q+L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDL 282



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 2/43 (4%)

Query: 6   CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           C  ++ C  +   C++ +C+N + SY CRC   Y L  +G  C
Sbjct: 400 CRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTC 441


>AF093119-1|AAC62108.1|  439|Homo sapiens UPH1 protein.
          Length = 439

 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 53/169 (31%), Positives = 73/169 (43%), Gaps = 22/169 (13%)

Query: 5   NCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR---CYGKV 59
           +C DVDEC ++   C+  Q C N  GSY C CP  Y  +  G  C D  + R   C  + 
Sbjct: 116 SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI--GPECVDIDECRYRYCQHRC 173

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQ-LCPGGPG 115
               G+  C+  +   + G     C  V     N CD   PC +    +Y   LC    G
Sbjct: 174 VNLPGSFRCQ-CEPGFQLGPNNRSCVDV-----NECDMGAPCEQRCFNSYGTFLCRCHQG 227

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
           Y+  L    +  + +DIDEC+    LC +  C N  G F C C  G+ L
Sbjct: 228 YE--LHRDGF--SCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGYQL 271



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 53/165 (32%), Positives = 72/165 (43%), Gaps = 25/165 (15%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCYGK 58
           G  C D+DEC+  + CQ+ +C+N  GS+ C+C P ++L  +  +C D  +    A C  +
Sbjct: 155 GPECVDIDECRY-RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQR 212

Query: 59  VDLRSGTETCR--DSDELSEDGTMAACC--CSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
                GT  CR     EL  DG   +    CS  +    Y C    EPG    R  C   
Sbjct: 213 CFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRC--VNEPG----RFSCHCP 266

Query: 114 PGYQPVLEPPSYVVTLADIDEC--AAHEGLCAHGTCTNTFGSFVC 156
            GYQ +           DIDEC   AH+   A  TC N  G + C
Sbjct: 267 QGYQLLA-----TRLCQDIDECESGAHQWSEAQ-TCVNFHGGYRC 305



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 52/225 (23%), Positives = 78/225 (34%), Gaps = 29/225 (12%)

Query: 5   NCTDVDECKS-PQSCQYG-QCINTQGSYTCRCPPNYELVSD------------------G 44
           NC DV+EC + P++C+   +CIN  G Y C  P +  +++D                   
Sbjct: 48  NCRDVNECLTIPEACKGEMKCINHYGGYLC-LPRSAAVINDLHGEGPPPPVPPVNTQPLP 106

Query: 45  TACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVG-AAWGNYCDPCPEPGS 103
           T      +  C    +       CR S +         C C  G    G  C    E   
Sbjct: 107 TGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRY 166

Query: 104 EAYRQLCPGGPGYQPVLEPPSYVV-----TLADIDECAAHEGLCAHGTCTNTFGSFVCTC 158
              +  C   PG       P + +     +  D++EC    G      C N++G+F+C C
Sbjct: 167 RYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM--GAPCEQRCFNSYGTFLCRC 224

Query: 159 GAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
             G+ L                       C N PG + C CP+GY
Sbjct: 225 HQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 269


>AY358336-1|AAQ88702.1|  509|Homo sapiens DFLL295 protein.
          Length = 509

 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 60/208 (28%), Positives = 76/208 (36%), Gaps = 51/208 (24%)

Query: 3   GFNCT-DVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G  C  D++EC   P+ C++ +C+NT GSY C C   Y L+ DG+               
Sbjct: 83  GKTCNQDLNECGLKPRPCKH-RCMNTYGSYKCYCLNGYMLMPDGSC-------------- 127

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
             S   TC          +MA C        G     CP PG      L P G       
Sbjct: 128 --SSALTC----------SMANCQYGCDVVKGQIRCQCPSPGLH----LAPDGR------ 165

Query: 121 EPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSL----APXXXXXXXXX 175
                  T  D+DECA     C     C NTFGS++C C  G+ L               
Sbjct: 166 -------TCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDEC 218

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
              +        C N+ GSY C C EGY
Sbjct: 219 SLGQYQCSSFARCYNVRGSYKCKCKEGY 246



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 4/46 (8%)

Query: 4   FNCTDVDECKSPQ-SCQ-YGQCINTQGSYTCRCPPNYELVSDGTAC 47
           + C D+DEC   Q  C  + +C N +GSY C+C   Y+   DG  C
Sbjct: 210 YQCHDIDECSLGQYQCSSFARCYNVRGSYKCKCKEGYQ--GDGLTC 253



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 24/69 (34%), Positives = 28/69 (40%), Gaps = 6/69 (8%)

Query: 142 CAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPE 201
           C HG C    G   C C  G+  A             +P  C    C N  GSY C C  
Sbjct: 64  CKHGEC---IGPNKCKCHPGY--AGKTCNQDLNECGLKPRPCKHR-CMNTYGSYKCYCLN 117

Query: 202 GYVAMPNGS 210
           GY+ MP+GS
Sbjct: 118 GYMLMPDGS 126


>AF193055-1|AAG22483.1|  474|Homo sapiens unknown protein.
          Length = 474

 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 52/165 (31%), Positives = 68/165 (41%), Gaps = 17/165 (10%)

Query: 8   DVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA---RC-YGKVDLR 62
           DV+EC   P+ CQ+ +C+NT GSY C C   + L+ D T C +SR      C Y   D  
Sbjct: 15  DVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDAT-CVNSRTCAMINCQYSCEDTE 72

Query: 63  SGTETCRDSDELSEDGTMAACC----CSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQP 118
            G +    S  L        C     C+ G     Y   C       Y   C    G++ 
Sbjct: 73  EGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYY---CKCHIGFE- 128

Query: 119 VLEPPSYVVTLADIDECAAHEGLCA-HGTCTNTFGSFVCTCGAGW 162
            L+  S      DI+EC      C+ H  C NT GSF C C  G+
Sbjct: 129 -LQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 172



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 5/78 (6%)

Query: 131 DIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSL---APXXXXXXXXXXXXRPDVCGPG 186
           DIDECA+ + +C +   C NTFGS+ C C  G+ L   +                 C   
Sbjct: 95  DIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHH 154

Query: 187 V-CRNLPGSYVCLCPEGY 203
             C N  GS+ C C +GY
Sbjct: 155 ANCFNTQGSFKCKCKQGY 172



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 22/51 (43%), Positives = 30/51 (58%), Gaps = 4/51 (7%)

Query: 3   GFNCTDVDECKSPQ-SCQYG-QCINTQGSYTCRCPPNYEL--VSDGTACYD 49
           G +C D+DEC S +  C Y  +C+NT GSY C+C   +EL  +S    C D
Sbjct: 90  GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCID 140



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 4/46 (8%)

Query: 4   FNCTDVDECK-SPQSCQY-GQCINTQGSYTCRCPPNYELVSDGTAC 47
           ++C D++EC     +C +   C NTQGS+ C+C   Y+   +G  C
Sbjct: 136 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYK--GNGLRC 179



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 5/84 (5%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           D++EC      C H  C NT GS+ C C +G  L P               +     C +
Sbjct: 15  DVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAM---INCQYSCED 70

Query: 191 LPGSYVCLCP-EGYVAMPNGSQYL 213
                 CLCP  G    PNG   L
Sbjct: 71  TEEGPQCLCPSSGLRLAPNGRDCL 94


>AF124486-1|AAG45245.1|  443|Homo sapiens fibulin-like extracellular
           matrix protein protein.
          Length = 443

 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 61/214 (28%), Positives = 83/214 (38%), Gaps = 27/214 (12%)

Query: 5   NCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR---CYGKV 59
           +C DVDEC ++    +  Q C N  GSY C CP  Y  +  G  C D  + R   C  + 
Sbjct: 120 SCVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYRKI--GPECVDIDECRYRYCQHRC 177

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQ-LCPGGPG 115
               G+  C+  +   + G     C  V     N CD   PC +    +Y   LC    G
Sbjct: 178 VNLPGSFRCQ-CEPGFQLGPNNRSCVDV-----NECDMGAPCEQRCFNSYGTFLCRCHQG 231

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           Y+  L    +  + +DIDEC+    LC +  C N  G F C C  G+ L           
Sbjct: 232 YE--LHRDGF--SCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGYQLLATRLCQDIDE 286

Query: 176 XXXRPDVCGPG-VCRNLPGSYVCL----CPEGYV 204
                  C     C N  G Y C+    C E Y+
Sbjct: 287 CESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYI 320



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 51/164 (31%), Positives = 71/164 (43%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRK----ARCYGK 58
           G  C D+DEC+  + CQ+ +C+N  GS+ C+C P ++L  +  +C D  +    A C  +
Sbjct: 159 GPECVDIDECRY-RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQR 216

Query: 59  VDLRSGTETCR--DSDELSEDGTMAACC--CSVGAAWGNY-CDPCPEPGSEAYRQLCPGG 113
                GT  CR     EL  DG   +    CS  +    Y C    EPG    R  C   
Sbjct: 217 CFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRC--VNEPG----RFSCHCP 270

Query: 114 PGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVC 156
            GYQ +           DIDEC +    C+   TC N  G + C
Sbjct: 271 QGYQLLA-----TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 48/178 (26%), Positives = 70/178 (39%), Gaps = 21/178 (11%)

Query: 34  CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSE----DG--TMAACCCSV 87
           CPP YE   D  +C D  +  C   +  R  ++ C +     +    DG   +   C  +
Sbjct: 109 CPPGYE-PDDQDSCVDVDE--CAQALHDRRPSQDCHNLSGSYQCTCPDGYRKIGPECVDI 165

Query: 88  GAAWGNYCDP-CPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG 145
                 YC   C   PGS  +R  C   PG+Q  L P +   +  D++EC    G     
Sbjct: 166 DECRYRYCQHRCVNLPGS--FRCQCE--PGFQ--LGPNNR--SCVDVNECDM--GAPCEQ 215

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
            C N++G+F+C C  G+ L                       C N PG + C CP+GY
Sbjct: 216 RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273


>X05495-1|CAA29045.1|  575|Homo sapiens thrombomodulin protein.
          Length = 575

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 54/163 (33%), Positives = 76/163 (46%), Gaps = 27/163 (16%)

Query: 6   CTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR----KARC-YGKV 59
           C DVD+C   P  C   +C+NTQG + C C PNY+LV DG  C +      +A C Y   
Sbjct: 323 CEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLV-DGE-CVEPVDPCFRANCEYQCQ 379

Query: 60  DLRSGTETCRDSD---ELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            L   +  C  ++    +  +       C+  A   + CDP  +   E     CP   GY
Sbjct: 380 PLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-CDPNTQASCE-----CP--EGY 431

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCG 159
             +L+   ++ T  DIDEC  + G C+ G C N  G+F C CG
Sbjct: 432 --ILDD-GFICT--DIDECE-NGGFCS-GVCHNLPGTFECICG 467



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 24/51 (47%), Positives = 30/51 (58%), Gaps = 3/51 (5%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSD-GTACYDSRK 52
           GF CTD+DEC++   C  G C N  G++ C C P+  LV   GT C DS K
Sbjct: 436 GFICTDIDECENGGFCS-GVCHNLPGTFECICGPDSALVRHIGTDC-DSGK 484



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 3/72 (4%)

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN--L 191
           +C+   G C H  C    G+  C C AG +L                D+C      N   
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302

Query: 192 PGSYVCLCPEGY 203
           PGSY C+C  GY
Sbjct: 303 PGSYSCMCETGY 314



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 47/179 (26%), Positives = 67/179 (37%), Gaps = 23/179 (12%)

Query: 28  GSYTCRCPPNYELVSDGTACYDS-----RKARCYGK-VDLRSGTET-CRDSDELSEDGTM 80
           GSY+C C   Y L +D   C D        + C  + V+ + G E  C  + +L  DG  
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGE- 361

Query: 81  AACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
             C   V   +   C+   +P ++    LC    G+ P+   P       +   C A   
Sbjct: 362 --CVEPVDPCFRANCEYQCQPLNQT-SYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-- 416

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
            C      NT  S  C C  G+ L                  C  GVC NLPG++ C+C
Sbjct: 417 -CD----PNTQAS--CECPEGYIL-DDGFICTDIDECENGGFCS-GVCHNLPGTFECIC 466



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 14/118 (11%)

Query: 93  NYCDPCPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTF 151
           ++C P P+ PGS  Y  +C    GY+   +         D+D+C      C    C NT 
Sbjct: 294 HFCVPNPDQPGS--YSCMCE--TGYRLAADQHR----CEDVDDCILEPSPCPQ-RCVNTQ 344

Query: 152 GSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNL-PGSYVCLCPEGYVAMPN 208
           G F C C   + L                  C    C+ L   SY+C+C EG+  +P+
Sbjct: 345 GGFECHCYPNYDLVDGECVEPVDPCFRAN--C-EYQCQPLNQTSYLCVCAEGFAPIPH 399



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 35/139 (25%), Positives = 43/139 (30%), Gaps = 15/139 (10%)

Query: 78  GTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADI 132
           G    C    GA  G++    P        +      C   PG  P  + P+     AD 
Sbjct: 219 GLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPG-APRCQCPAGAALQADG 277

Query: 133 DECAAH-----EGLCAHGTCTNTF--GSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCG 184
             C A        LC H    N    GS+ C C  G+ LA               P  C 
Sbjct: 278 RSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC- 336

Query: 185 PGVCRNLPGSYVCLCPEGY 203
           P  C N  G + C C   Y
Sbjct: 337 PQRCVNTQGGFECHCYPNY 355


>D00210-1|BAA00149.1|  575|Homo sapiens thrombomodulin precursor
           protein.
          Length = 575

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 54/163 (33%), Positives = 76/163 (46%), Gaps = 27/163 (16%)

Query: 6   CTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR----KARC-YGKV 59
           C DVD+C   P  C   +C+NTQG + C C PNY+LV DG  C +      +A C Y   
Sbjct: 323 CEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLV-DGE-CVEPVDPCFRANCEYQCQ 379

Query: 60  DLRSGTETCRDSD---ELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            L   +  C  ++    +  +       C+  A   + CDP  +   E     CP   GY
Sbjct: 380 PLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-CDPNTQASCE-----CP--EGY 431

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCG 159
             +L+   ++ T  DIDEC  + G C+ G C N  G+F C CG
Sbjct: 432 --ILDD-GFICT--DIDECE-NGGFCS-GVCHNLPGTFECICG 467



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 24/51 (47%), Positives = 30/51 (58%), Gaps = 3/51 (5%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSD-GTACYDSRK 52
           GF CTD+DEC++   C  G C N  G++ C C P+  LV   GT C DS K
Sbjct: 436 GFICTDIDECENGGFCS-GVCHNLPGTFECICGPDSALVRHIGTDC-DSGK 484



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 3/72 (4%)

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN--L 191
           +C+   G C H  C    G+  C C AG +L                D+C      N   
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302

Query: 192 PGSYVCLCPEGY 203
           PGSY C+C  GY
Sbjct: 303 PGSYSCMCETGY 314



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 47/179 (26%), Positives = 67/179 (37%), Gaps = 23/179 (12%)

Query: 28  GSYTCRCPPNYELVSDGTACYDS-----RKARCYGK-VDLRSGTET-CRDSDELSEDGTM 80
           GSY+C C   Y L +D   C D        + C  + V+ + G E  C  + +L  DG  
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGE- 361

Query: 81  AACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
             C   V   +   C+   +P ++    LC    G+ P+   P       +   C A   
Sbjct: 362 --CVEPVDPCFRANCEYQCQPLNQT-SYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-- 416

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
            C      NT  S  C C  G+ L                  C  GVC NLPG++ C+C
Sbjct: 417 -CD----PNTQAS--CECPEGYIL-DDGFICTDIDECENGGFCS-GVCHNLPGTFECIC 466



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 14/118 (11%)

Query: 93  NYCDPCPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTF 151
           ++C P P+ PGS  Y  +C    GY+   +         D+D+C      C    C NT 
Sbjct: 294 HFCVPNPDQPGS--YSCMCE--TGYRLAADQHR----CEDVDDCILEPSPCPQ-RCVNTQ 344

Query: 152 GSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNL-PGSYVCLCPEGYVAMPN 208
           G F C C   + L                  C    C+ L   SY+C+C EG+  +P+
Sbjct: 345 GGFECHCYPNYDLVDGECVEPVDPCFRAN--C-EYQCQPLNQTSYLCVCAEGFAPIPH 399



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 35/139 (25%), Positives = 43/139 (30%), Gaps = 15/139 (10%)

Query: 78  GTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADI 132
           G    C    GA  G++    P        +      C   PG  P  + P+     AD 
Sbjct: 219 GLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPG-APRCQCPAGAALQADG 277

Query: 133 DECAAH-----EGLCAHGTCTNTF--GSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCG 184
             C A        LC H    N    GS+ C C  G+ LA               P  C 
Sbjct: 278 RSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC- 336

Query: 185 PGVCRNLPGSYVCLCPEGY 203
           P  C N  G + C C   Y
Sbjct: 337 PQRCVNTQGGFECHCYPNY 355


>BC035602-1|AAH35602.2|  575|Homo sapiens thrombomodulin protein.
          Length = 575

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 54/163 (33%), Positives = 76/163 (46%), Gaps = 27/163 (16%)

Query: 6   CTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSR----KARC-YGKV 59
           C DVD+C   P  C   +C+NTQG + C C PNY+LV DG  C +      +A C Y   
Sbjct: 323 CEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLV-DGE-CVEPVDPCFRANCEYQCQ 379

Query: 60  DLRSGTETCRDSD---ELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
            L   +  C  ++    +  +       C+  A   + CDP  +   E     CP   GY
Sbjct: 380 PLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-CDPNTQASCE-----CP--EGY 431

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCG 159
             +L+   ++ T  DIDEC  + G C+ G C N  G+F C CG
Sbjct: 432 --ILDD-GFICT--DIDECE-NGGFCS-GVCHNLPGTFECICG 467



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 24/51 (47%), Positives = 30/51 (58%), Gaps = 3/51 (5%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSD-GTACYDSRK 52
           GF CTD+DEC++   C  G C N  G++ C C P+  LV   GT C DS K
Sbjct: 436 GFICTDIDECENGGFCS-GVCHNLPGTFECICGPDSALVRHIGTDC-DSGK 484



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 3/72 (4%)

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN--L 191
           +C+   G C H  C    G+  C C AG +L                D+C      N   
Sbjct: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302

Query: 192 PGSYVCLCPEGY 203
           PGSY C+C  GY
Sbjct: 303 PGSYSCMCETGY 314



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 47/179 (26%), Positives = 67/179 (37%), Gaps = 23/179 (12%)

Query: 28  GSYTCRCPPNYELVSDGTACYDS-----RKARCYGK-VDLRSGTET-CRDSDELSEDGTM 80
           GSY+C C   Y L +D   C D        + C  + V+ + G E  C  + +L  DG  
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGE- 361

Query: 81  AACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
             C   V   +   C+   +P ++    LC    G+ P+   P       +   C A   
Sbjct: 362 --CVEPVDPCFRANCEYQCQPLNQT-SYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD-- 416

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLC 199
            C      NT  S  C C  G+ L                  C  GVC NLPG++ C+C
Sbjct: 417 -CD----PNTQAS--CECPEGYIL-DDGFICTDIDECENGGFCS-GVCHNLPGTFECIC 466



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 14/118 (11%)

Query: 93  NYCDPCPE-PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTF 151
           ++C P P+ PGS  Y  +C    GY+   +         D+D+C      C    C NT 
Sbjct: 294 HFCVPNPDQPGS--YSCMCE--TGYRLAADQHR----CEDVDDCILEPSPCPQ-RCVNTQ 344

Query: 152 GSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNL-PGSYVCLCPEGYVAMPN 208
           G F C C   + L                  C    C+ L   SY+C+C EG+  +P+
Sbjct: 345 GGFECHCYPNYDLVDGECVEPVDPCFRAN--C-EYQCQPLNQTSYLCVCAEGFAPIPH 399



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 35/139 (25%), Positives = 43/139 (30%), Gaps = 15/139 (10%)

Query: 78  GTMAACCCSVGAAWGNYCDPCP-----EPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADI 132
           G    C    GA  G++    P        +      C   PG  P  + P+     AD 
Sbjct: 219 GLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPG-APRCQCPAGAALQADG 277

Query: 133 DECAAH-----EGLCAHGTCTNTF--GSFVCTCGAGWSLAPXXXX-XXXXXXXXRPDVCG 184
             C A        LC H    N    GS+ C C  G+ LA               P  C 
Sbjct: 278 RSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC- 336

Query: 185 PGVCRNLPGSYVCLCPEGY 203
           P  C N  G + C C   Y
Sbjct: 337 PQRCVNTQGGFECHCYPNY 355


>AC010895-1|AAY14669.1|  320|Homo sapiens unknown protein.
          Length = 320

 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 54/213 (25%), Positives = 78/213 (36%), Gaps = 27/213 (12%)

Query: 9   VDECKS-PQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKAR----CYGKVDLR 62
           +DEC +   +C+  Q CIN +GS+ C+CPP Y+    G  C D  +      C+ +    
Sbjct: 1   IDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQCVDIDECTIPPYCHQRCVNT 58

Query: 63  SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL----CPGGPGYQP 118
            G+  C+ S           C         N CD   +   + Y  L    C    GY  
Sbjct: 59  PGSFYCQCSPGFQLAANNYTCVDI------NECDASNQCAQQCYNILGSFICQCNQGY-- 110

Query: 119 VLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
             E  S  +   DIDEC     LC +  C N  G F C C  G+ +              
Sbjct: 111 --ELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQVVRSRTCQDINECET 167

Query: 179 RPDVCGPGVCRNLPGSYVCL----CPEGYVAMP 207
             +     +C N  G + C     C + Y+  P
Sbjct: 168 TNECREDEMCWNYHGGFRCYPRNPCQDPYILTP 200



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 23/164 (14%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA--------R 54
           G  C D+DEC  P  C + +C+NT GS+ C+C P ++L ++   C D  +         +
Sbjct: 36  GEQCVDIDECTIPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ 94

Query: 55  CYGKVDLRSGTETCRDSDELSEDGTMAACC--CSVGAAWGNYCDPCPEPGSEAYRQLCPG 112
           CY    L S    C    ELS D         C   +    Y     EPG   +  +CP 
Sbjct: 95  CYN--ILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGK--FSCMCP- 148

Query: 113 GPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVC 156
             GYQ V        T  DI+EC           C N  G F C
Sbjct: 149 -QGYQVVRSR-----TCQDINECETTNECREDEMCWNYHGGFRC 186



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 26/78 (33%), Positives = 29/78 (37%), Gaps = 4/78 (5%)

Query: 132 IDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRN 190
           IDEC A    C A   C N  GSF C C  G+                 P  C    C N
Sbjct: 1   IDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTI--PPYCHQR-CVN 57

Query: 191 LPGSYVCLCPEGYVAMPN 208
            PGS+ C C  G+    N
Sbjct: 58  TPGSFYCQCSPGFQLAAN 75


>AY358895-1|AAQ89254.1|  915|Homo sapiens MATN2 protein.
          Length = 915

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 53/189 (28%), Positives = 72/189 (38%), Gaps = 15/189 (7%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTAC-----YDSRKARCYGKVDLRSGTETCR--DSDELS 75
           CIN  GSY CRC   Y L SD T C            C        G+  C+      L+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312

Query: 76  EDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDEC 135
           EDG          A+  + C+        +Y  LC    G+   L P     T   I+ C
Sbjct: 313 EDGKRCV-AVDYCASENHGCEHECVNADGSY--LCQCHEGF--ALNPDE--KTCTRINYC 365

Query: 136 AAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSY 195
           A ++  C H  C N   S+ C C  G++L P            + D     +C N   S+
Sbjct: 366 ALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSF 424

Query: 196 VCLCPEGYV 204
           VC C EG++
Sbjct: 425 VCQCSEGFL 433



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 56/215 (26%), Positives = 85/215 (39%), Gaps = 19/215 (8%)

Query: 6   CTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC----YGKVD 60
           CT ++ C  +   C++ +C+N + SY CRC   Y L  +G  C  SR   C    +G   
Sbjct: 359 CTRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTC--SRVDHCAQQDHGCEQ 415

Query: 61  LRSGTE---TCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGY 116
           L   TE    C+ S+    +  +  C         ++ C+        ++   CP G   
Sbjct: 416 LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGH-- 473

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
             VL       T A +D CA  +  C H +C ++  SFVC C  G+ L            
Sbjct: 474 --VLRSDGK--TCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDV 528

Query: 177 XXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNGSQ 211
               D     +C N   SY C C EG+    +G +
Sbjct: 529 CQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKR 563



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 23/218 (10%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
           G  C+ VD C +    C+   C+NT+ S+ C+C   + +  D   C  SR   C      
Sbjct: 397 GKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTC--SRVDYCLLSDHG 453

Query: 56  --YGKVDL-RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCP 111
             Y  V++ RS    C +   L  DG    C      A G++ C+       +++  +C 
Sbjct: 454 CEYSCVNMDRSFACQCPEGHVLRSDG--KTCAKLDSCALGDHGCEHSCVSSEDSF--VCQ 509

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXX 171
              GY  +L          D+  C A +  C H  C N+  S+ C C  G+ LA      
Sbjct: 510 CFEGY--ILREDGKTCRRKDV--CQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRC 564

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                          +C N   SY+C C EG+V   +G
Sbjct: 565 RRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDG 602



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGS 194
           C+  E  CAH  C N  GS+VC C  G+ L                D     +C N+PGS
Sbjct: 242 CSTLEHNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGS 300

Query: 195 YVCLCPEGYVAMPNGSQ 211
           +VC C  GY    +G +
Sbjct: 301 FVCQCYSGYALAEDGKR 317



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 51/214 (23%), Positives = 80/214 (37%), Gaps = 15/214 (7%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQCINTQGSYTCRCPPNYELVSDGTAC----YDS-RKARCY 56
           G  C  VD C S    C++ +C+N  GSY C+C   + L  D   C    Y +  K  C 
Sbjct: 315 GKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTRINYCALNKPGCE 373

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPG 115
            +      +  CR     + D     C      A  ++ C+       +++  +C    G
Sbjct: 374 HECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSF--VCQCSEG 431

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
           +  + E    + T + +D C   +  C + +C N   SF C C  G  L           
Sbjct: 432 FL-INED---LKTCSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLD 486

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                D      C +   S+VC C EGY+   +G
Sbjct: 487 SCALGDHGCEHSCVSSEDSFVCQCFEGYILREDG 520



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 133 DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLP 192
           D CA  +  C    C N  GSFVC C +G++LA               +      C N  
Sbjct: 281 DLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNAD 339

Query: 193 GSYVCLCPEGYVAMPN 208
           GSY+C C EG+   P+
Sbjct: 340 GSYLCQCHEGFALNPD 355



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 9/90 (10%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC--YDSRKARCYG-- 57
           G  C   D C++    C++  C+N+  SYTC C   + L  DG  C   D  K+  +G  
Sbjct: 520 GKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCE 578

Query: 58  KVDLRSGTE---TCRDSDELSEDGTMAACC 84
            + + +G      C +   L+EDG     C
Sbjct: 579 HICVNNGNSYICKCSEGFVLAEDGRRCKKC 608



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/30 (43%), Positives = 20/30 (66%)

Query: 188 CRNLPGSYVCLCPEGYVAMPNGSQYLLQNL 217
           C N+PGSYVC C +GY+   + +   +Q+L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDL 282


>AB023961-1|BAB20317.1|  502|Homo sapiens notch4 protein.
          Length = 502

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 55/215 (25%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 1   MPGFN---CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYE---LVSDGTACYDS---- 50
           MPG+    C   D C +      G C+ T     C CPP +E      D   C+      
Sbjct: 145 MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 204

Query: 51  -RKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL 109
            +   C+    L S    C    E       A  C   G + G  C   PE  S  +  L
Sbjct: 205 PKGTSCHN--TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 262

Query: 110 CPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXX 168
           CP  PG+   + P   V    + D C +H+  C + GTC +   ++ C C   W+     
Sbjct: 263 CP--PGF---IGPGCEV----NPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGWDCS 311

Query: 169 XXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                      P     G C+N  GS+ C+C  G+
Sbjct: 312 EDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGW 346



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 64/210 (30%), Positives = 87/210 (41%), Gaps = 27/210 (12%)

Query: 3   GFNCT-DVDECKS--PQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCY-G 57
           G++C+ DVDEC++  P  C+ G  C N+ GS+ C C   +   S      D   A C  G
Sbjct: 307 GWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG 366

Query: 58  KVDL-RSGTETCR-DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPG 115
              + R G+ +C            +   C S        C   P  GS     LC   PG
Sbjct: 367 STCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST----LCLCQPG 422

Query: 116 YQPVLEPPSYVVTLADIDECA-AHEGL--CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXX 171
           Y     P  +     D+DEC  A +G   C HG +C NT GSF C C  G++        
Sbjct: 423 YSG---PTCH----QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--GSRCEA 473

Query: 172 XXXXXXXRPDVCGPG-VCRNLPGSYVCLCP 200
                  +P  C PG  C +L  ++ CLCP
Sbjct: 474 DHNECLSQP--CHPGSTCLDLLATFHCLCP 501



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 63/218 (28%), Positives = 81/218 (37%), Gaps = 32/218 (14%)

Query: 2   PGF---NC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCY 56
           PGF    C  + D C S Q    G C +   +YTC CP  +     G  C  D  +    
Sbjct: 265 PGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT----GWDCSEDVDECEAQ 320

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLC-PGGP- 114
           G    R+G  TC++S      G+    C S    WG     C E   +     C PG   
Sbjct: 321 GPPHCRNGG-TCQNSA-----GSFHCVCVS---GWGG--TSCEENLDDCIAATCAPGSTC 369

Query: 115 ----GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTC-TNTF-GSFVCTCGAGWSLAPXX 168
               G    L PP     L  +++    +       C TN   GS +C C  G+S  P  
Sbjct: 370 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS-GPTC 428

Query: 169 XXXXXXXXXXR--PDVCGPG-VCRNLPGSYVCLCPEGY 203
                     +  P  C  G  C N PGS+ CLCP GY
Sbjct: 429 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 466



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 131 DIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VC 188
           D++EC    G C  GT C NT GSF C C  G    P             P  C  G  C
Sbjct: 193 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GPRCELRAGPCP---PRGCSNGGTC 248

Query: 189 RNLPGS----YVCLCPEGYV 204
           + +P      ++CLCP G++
Sbjct: 249 QLMPEKDSTFHLCLCPPGFI 268


>Y00692-1|CAA68687.1|  676|Homo sapiens preproprotein S protein.
          Length = 676

 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 29/77 (37%), Positives = 41/77 (53%), Gaps = 5/77 (6%)

Query: 131 DIDEC---AAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCGPG 186
           DI+EC   +   G C+   C NT GS+ C+C  G+  L+             +P +CG  
Sbjct: 157 DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215

Query: 187 VCRNLPGSYVCLCPEGY 203
           VC+N+PG + C CPEGY
Sbjct: 216 VCKNIPGDFECECPEGY 232



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 34/144 (23%), Positives = 51/144 (35%), Gaps = 14/144 (9%)

Query: 68  CRDSDELSEDGTMAACCCSVGAAW-GNYCD----PCPEPGS--EAYRQLCPGGPGYQPVL 120
           C +   +S     A+  C+    W G  C+     C +P +      Q+C   PG     
Sbjct: 126 CNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCS 185

Query: 121 EPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               +V+        D+DEC+    +C    C N  G F C C  G+             
Sbjct: 186 CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDID 245

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLC 199
                ++C   +C N PG Y C C
Sbjct: 246 ECSE-NMCAQ-LCVNYPGGYTCYC 267



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           +C DVDEC   P  C    C N  G + C CP  Y       +C D
Sbjct: 198 DCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 33/114 (28%), Positives = 46/114 (40%), Gaps = 15/114 (13%)

Query: 8   DVDECKSPQSCQYGQ---CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           D++ECK P +   G    C NT GSY C C   + ++S+   C D  +  C  K  +  G
Sbjct: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDE--CSLKPSI-CG 213

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLCPGGPG 115
           T  C++     E      C C  G  +      C+   E       QLC   PG
Sbjct: 214 TAVCKNIPGDFE------CECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPG 261



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 19/63 (30%), Positives = 25/63 (39%)

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
           +C +   SF CTC  GW                  +     +C N PGSY C C  G+V 
Sbjct: 133 SCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 192

Query: 206 MPN 208
           + N
Sbjct: 193 LSN 195



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 4/45 (8%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRC--PPNYELVSDGTAC 47
           +C D+DEC      Q   C+N  G YTC C     ++L  D  +C
Sbjct: 240 SCEDIDECSENMCAQL--CVNYPGGYTCYCDGKKGFKLAQDQKSC 282


>M57853-1|AAA60357.1|  676|Homo sapiens S protein protein.
          Length = 676

 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 29/77 (37%), Positives = 41/77 (53%), Gaps = 5/77 (6%)

Query: 131 DIDEC---AAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCGPG 186
           DI+EC   +   G C+   C NT GS+ C+C  G+  L+             +P +CG  
Sbjct: 157 DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215

Query: 187 VCRNLPGSYVCLCPEGY 203
           VC+N+PG + C CPEGY
Sbjct: 216 VCKNIPGDFECECPEGY 232



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 34/144 (23%), Positives = 51/144 (35%), Gaps = 14/144 (9%)

Query: 68  CRDSDELSEDGTMAACCCSVGAAW-GNYCD----PCPEPGS--EAYRQLCPGGPGYQPVL 120
           C +   +S     A+  C+    W G  C+     C +P +      Q+C   PG     
Sbjct: 126 CNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCS 185

Query: 121 EPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               +V+        D+DEC+    +C    C N  G F C C  G+             
Sbjct: 186 CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDID 245

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLC 199
                ++C   +C N PG Y C C
Sbjct: 246 ECSE-NMCAQ-LCVNYPGGYTCYC 267



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           +C DVDEC   P  C    C N  G + C CP  Y       +C D
Sbjct: 198 DCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 33/114 (28%), Positives = 46/114 (40%), Gaps = 15/114 (13%)

Query: 8   DVDECKSPQSCQYGQ---CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           D++ECK P +   G    C NT GSY C C   + ++S+   C D  +  C  K  +  G
Sbjct: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDE--CSLKPSI-CG 213

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLCPGGPG 115
           T  C++     E      C C  G  +      C+   E       QLC   PG
Sbjct: 214 TAVCKNIPGDFE------CECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPG 261



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 19/63 (30%), Positives = 25/63 (39%)

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
           +C +   SF CTC  GW                  +     +C N PGSY C C  G+V 
Sbjct: 133 SCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 192

Query: 206 MPN 208
           + N
Sbjct: 193 LSN 195



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 4/45 (8%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRC--PPNYELVSDGTAC 47
           +C D+DEC      Q   C+N  G YTC C     ++L  D  +C
Sbjct: 240 SCEDIDECSENMCAQL--CVNYPGGYTCYCDGKKGFKLAQDQKSC 282


>M36564-1|AAA60180.1|  650|Homo sapiens PROS1 protein.
          Length = 650

 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 29/77 (37%), Positives = 41/77 (53%), Gaps = 5/77 (6%)

Query: 131 DIDEC---AAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCGPG 186
           DI+EC   +   G C+   C NT GS+ C+C  G+  L+             +P +CG  
Sbjct: 131 DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 189

Query: 187 VCRNLPGSYVCLCPEGY 203
           VC+N+PG + C CPEGY
Sbjct: 190 VCKNIPGDFECECPEGY 206



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 34/144 (23%), Positives = 51/144 (35%), Gaps = 14/144 (9%)

Query: 68  CRDSDELSEDGTMAACCCSVGAAW-GNYCD----PCPEPGS--EAYRQLCPGGPGYQPVL 120
           C +   +S     A+  C+    W G  C+     C +P +      Q+C   PG     
Sbjct: 100 CNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCS 159

Query: 121 EPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               +V+        D+DEC+    +C    C N  G F C C  G+             
Sbjct: 160 CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDID 219

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLC 199
                ++C   +C N PG Y C C
Sbjct: 220 ECSE-NMCAQ-LCVNYPGGYTCYC 241



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           +C DVDEC   P  C    C N  G + C CP  Y       +C D
Sbjct: 172 DCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 217



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 33/114 (28%), Positives = 46/114 (40%), Gaps = 15/114 (13%)

Query: 8   DVDECKSPQSCQYGQ---CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           D++ECK P +   G    C NT GSY C C   + ++S+   C D  +  C  K  +  G
Sbjct: 131 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDE--CSLKPSI-CG 187

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLCPGGPG 115
           T  C++     E      C C  G  +      C+   E       QLC   PG
Sbjct: 188 TAVCKNIPGDFE------CECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPG 235



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 19/63 (30%), Positives = 25/63 (39%)

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
           +C +   SF CTC  GW                  +     +C N PGSY C C  G+V 
Sbjct: 107 SCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 166

Query: 206 MPN 208
           + N
Sbjct: 167 LSN 169



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 4/45 (8%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRC--PPNYELVSDGTAC 47
           +C D+DEC      Q   C+N  G YTC C     ++L  D  +C
Sbjct: 214 SCEDIDECSENMCAQL--CVNYPGGYTCYCDGKKGFKLAQDQKSC 256


>M15036-1|AAA36479.1|  676|Homo sapiens protein ( Human vitamin
           K-dependent plasma protein S mRNA, complete cds. ).
          Length = 676

 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 29/77 (37%), Positives = 41/77 (53%), Gaps = 5/77 (6%)

Query: 131 DIDEC---AAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCGPG 186
           DI+EC   +   G C+   C NT GS+ C+C  G+  L+             +P +CG  
Sbjct: 157 DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215

Query: 187 VCRNLPGSYVCLCPEGY 203
           VC+N+PG + C CPEGY
Sbjct: 216 VCKNIPGDFECECPEGY 232



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 34/144 (23%), Positives = 51/144 (35%), Gaps = 14/144 (9%)

Query: 68  CRDSDELSEDGTMAACCCSVGAAW-GNYCD----PCPEPGS--EAYRQLCPGGPGYQPVL 120
           C +   +S     A+  C+    W G  C+     C +P +      Q+C   PG     
Sbjct: 126 CNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCS 185

Query: 121 EPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               +V+        D+DEC+    +C    C N  G F C C  G+             
Sbjct: 186 CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDID 245

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLC 199
                ++C   +C N PG Y C C
Sbjct: 246 ECSE-NMCAQ-LCVNYPGGYTCYC 267



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           +C DVDEC   P  C    C N  G + C CP  Y       +C D
Sbjct: 198 DCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 33/114 (28%), Positives = 46/114 (40%), Gaps = 15/114 (13%)

Query: 8   DVDECKSPQSCQYGQ---CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           D++ECK P +   G    C NT GSY C C   + ++S+   C D  +  C  K  +  G
Sbjct: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDE--CSLKPSI-CG 213

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLCPGGPG 115
           T  C++     E      C C  G  +      C+   E       QLC   PG
Sbjct: 214 TAVCKNIPGDFE------CECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPG 261



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 19/63 (30%), Positives = 25/63 (39%)

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
           +C +   SF CTC  GW                  +     +C N PGSY C C  G+V 
Sbjct: 133 SCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 192

Query: 206 MPN 208
           + N
Sbjct: 193 LSN 195



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 4/45 (8%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRC--PPNYELVSDGTAC 47
           +C D+DEC      Q   C+N  G YTC C     ++L  D  +C
Sbjct: 240 SCEDIDECSENMCAQL--CVNYPGGYTCYCDGKKGFKLAQDQKSC 282


>BC015801-1|AAH15801.1|  676|Homo sapiens PROS1 protein protein.
          Length = 676

 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 29/77 (37%), Positives = 41/77 (53%), Gaps = 5/77 (6%)

Query: 131 DIDEC---AAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCGPG 186
           DI+EC   +   G C+   C NT GS+ C+C  G+  L+             +P +CG  
Sbjct: 157 DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215

Query: 187 VCRNLPGSYVCLCPEGY 203
           VC+N+PG + C CPEGY
Sbjct: 216 VCKNIPGDFECECPEGY 232



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 34/144 (23%), Positives = 51/144 (35%), Gaps = 14/144 (9%)

Query: 68  CRDSDELSEDGTMAACCCSVGAAW-GNYCD----PCPEPGS--EAYRQLCPGGPGYQPVL 120
           C +   +S     A+  C+    W G  C+     C +P +      Q+C   PG     
Sbjct: 126 CNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCS 185

Query: 121 EPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               +V+        D+DEC+    +C    C N  G F C C  G+             
Sbjct: 186 CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDID 245

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLC 199
                ++C   +C N PG Y C C
Sbjct: 246 ECSE-NMCAQ-LCVNYPGGYTCYC 267



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           +C DVDEC   P  C    C N  G + C CP  Y       +C D
Sbjct: 198 DCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 33/114 (28%), Positives = 46/114 (40%), Gaps = 15/114 (13%)

Query: 8   DVDECKSPQSCQYGQ---CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           D++ECK P +   G    C NT GSY C C   + ++S+   C D  +  C  K  +  G
Sbjct: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDE--CSLKPSI-CG 213

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLCPGGPG 115
           T  C++     E      C C  G  +      C+   E       QLC   PG
Sbjct: 214 TAVCKNIPGDFE------CECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPG 261



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 19/63 (30%), Positives = 25/63 (39%)

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
           +C +   SF CTC  GW                  +     +C N PGSY C C  G+V 
Sbjct: 133 SCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 192

Query: 206 MPN 208
           + N
Sbjct: 193 LSN 195



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 4/45 (8%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRC--PPNYELVSDGTAC 47
           +C D+DEC      Q   C+N  G YTC C     ++L  D  +C
Sbjct: 240 SCEDIDECSENMCAQL--CVNYPGGYTCYCDGKKGFKLAQDQKSC 282


>AY308744-1|AAP45054.1|  497|Homo sapiens protein S (alpha) protein.
          Length = 497

 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 29/77 (37%), Positives = 41/77 (53%), Gaps = 5/77 (6%)

Query: 131 DIDEC---AAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCGPG 186
           DI+EC   +   G C+   C NT GS+ C+C  G+  L+             +P +CG  
Sbjct: 157 DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215

Query: 187 VCRNLPGSYVCLCPEGY 203
           VC+N+PG + C CPEGY
Sbjct: 216 VCKNIPGDFECECPEGY 232



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 34/144 (23%), Positives = 51/144 (35%), Gaps = 14/144 (9%)

Query: 68  CRDSDELSEDGTMAACCCSVGAAW-GNYCD----PCPEPGS--EAYRQLCPGGPGYQPVL 120
           C +   +S     A+  C+    W G  C+     C +P +      Q+C   PG     
Sbjct: 126 CNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCS 185

Query: 121 EPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               +V+        D+DEC+    +C    C N  G F C C  G+             
Sbjct: 186 CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDID 245

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLC 199
                ++C   +C N PG Y C C
Sbjct: 246 ECSE-NMCAQ-LCVNYPGGYTCYC 267



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 5   NCTDVDECK-SPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           +C DVDEC   P  C    C N  G + C CP  Y       +C D
Sbjct: 198 DCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 33/114 (28%), Positives = 46/114 (40%), Gaps = 15/114 (13%)

Query: 8   DVDECKSPQSCQYGQ---CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           D++ECK P +   G    C NT GSY C C   + ++S+   C D  +  C  K  +  G
Sbjct: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDE--CSLKPSI-CG 213

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLCPGGPG 115
           T  C++     E      C C  G  +      C+   E       QLC   PG
Sbjct: 214 TAVCKNIPGDFE------CECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPG 261



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 19/63 (30%), Positives = 25/63 (39%)

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
           +C +   SF CTC  GW                  +     +C N PGSY C C  G+V 
Sbjct: 133 SCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 192

Query: 206 MPN 208
           + N
Sbjct: 193 LSN 195



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 4/45 (8%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRC--PPNYELVSDGTAC 47
           +C D+DEC      Q   C+N  G YTC C     ++L  D  +C
Sbjct: 240 SCEDIDECSENMCAQL--CVNYPGGYTCYCDGKKGFKLAQDQKSC 282


>AF011407-1|AAB64201.1|  180|Homo sapiens latent TGF beta binding
           protein 3 protein.
          Length = 180

 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 20/38 (52%), Positives = 25/38 (65%)

Query: 79  TMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
           T   CCCSVG AWG  C  CP  G+ A++++CP G GY
Sbjct: 31  TRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGY 68


>BC127263-1|AAI27264.1|  363|Homo sapiens SCUBE1 protein protein.
          Length = 363

 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 54/201 (26%), Positives = 71/201 (35%), Gaps = 21/201 (10%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
           G NC + D       C +      +G   C C P ++L  +   C  +      G     
Sbjct: 163 GMNCMNKDH-----GCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSC 217

Query: 63  SGTET-----CRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQ 117
             T+T     C     L  DG      C+V       CD   +  +   R  CP G   Q
Sbjct: 218 EDTDTGPMCGCHQKYALHSDGRTCIETCAVN---NGGCDRTCKDTATGVRCSCPVGFTLQ 274

Query: 118 PVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXX 177
           P  +      T  DI+EC  + G C H  C NT GSF C C  G+ L             
Sbjct: 275 PDGK------TCKDINECLVNNGGCDH-FCRNTVGSFECGCRKGYKLLTDERTCQDIDEC 327

Query: 178 XRPDVCGPGVCRNLPGSYVCL 198
                C   +C N PGS+ CL
Sbjct: 328 SFERTC-DHICINSPGSFQCL 347



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 55/209 (26%), Positives = 75/209 (35%), Gaps = 16/209 (7%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACY--DSRKARCYGKVD 60
           G NC DVDEC+         C+N  GSY C+C   + L  +   C    +    C  K  
Sbjct: 112 GHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKD- 170

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVG---AAWGNYCDPCPEPGSEAYRQLCPG---GP 114
                  CR   E  + G   AC C  G   A     C      G+   +  C     GP
Sbjct: 171 -HGCAHICR---ETPKGG--VACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGP 224

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXX 174
                 +   +      I+ CA + G C   TC +T     C+C  G++L P        
Sbjct: 225 MCGCHQKYALHSDGRTCIETCAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTCKDI 283

Query: 175 XXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                 +      CRN  GS+ C C +GY
Sbjct: 284 NECLVNNGGCDHFCRNTVGSFECGCRKGY 312



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 34/119 (28%), Positives = 44/119 (36%), Gaps = 7/119 (5%)

Query: 96  DPCPEPGSEAYRQ-LCPGGPGYQPVLEPPSYV---VTLADIDECAA--HEGLCAHGTCTN 149
           D C E   + +   +C   P     L  P Y        DIDEC    + G C H  C N
Sbjct: 35  DECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVH-ECIN 93

Query: 150 TFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPN 208
             G++ CTC  G+ LA               +     +C N  GSY C C  G+    N
Sbjct: 94  IPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDN 152



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 4/50 (8%)

Query: 3   GFNCTDVDECKSPQ---SCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
           G  C D+DEC++      C + +CIN  G+Y C C   + L  DG  C D
Sbjct: 69  GKQCEDIDECENDYYNGGCVH-ECINIPGNYRCTCFDGFMLAHDGHNCLD 117



 Score = 34.3 bits (75), Expect = 0.36
 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 6/51 (11%)

Query: 1  MPGFNCTDVDEC-KSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYD 49
          +PG    DVDEC +    C     C NT  SY C C P Y+   +G  C D
Sbjct: 28 LPG--SVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCED 74


>AK027775-1|BAB55358.1|  537|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14869 fis, clone PLACE1002474, moderately
           similar to Mus musculus matrilin-2 precursor mRNA. ).
          Length = 537

 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 23/218 (10%)

Query: 3   GFNCTDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARC------ 55
           G  C+ VD C +    C+   C+NT+ S+ C+C   + +  D   C  SR   C      
Sbjct: 19  GKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLMTC--SRVDYCLLSDHG 75

Query: 56  --YGKVDL-RSGTETCRDSDELSEDGTMAACCCSVGAAWGNY-CDPCPEPGSEAYRQLCP 111
             Y  V++ RS    C +   L  DG    C      A G++ C+       +++  +C 
Sbjct: 76  CEYSCVNMDRSFACQCPEGHVLRSDG--KTCAKLDSCALGDHGCEHSCVSSEDSF--VCQ 131

Query: 112 GGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXX 171
              GY  +L          D+  C A +  C H  C N+  S+ C C  G+ LA      
Sbjct: 132 CFEGY--ILREDGKTCRRKDV--CQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRC 186

Query: 172 XXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
                          +C N   SY+C C EG+V   +G
Sbjct: 187 RRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDG 224



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 50/191 (26%), Positives = 71/191 (37%), Gaps = 17/191 (8%)

Query: 29  SYTCRCPPNYELVSDGTACYDSRKARC----YGKVDLRSGTE---TCRDSDELSEDGTMA 81
           SY CRC   Y L  +G  C  SR   C    +G   L   TE    C+ S+    +  + 
Sbjct: 4   SYYCRCHRGYTLDPNGKTC--SRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLM 61

Query: 82  ACCCSVGAAWGNY-CDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEG 140
            C         ++ C+        ++   CP G     VL       T A +D CA  + 
Sbjct: 62  TCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGH----VLRSDGK--TCAKLDSCALGDH 115

Query: 141 LCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
            C H +C ++  SFVC C  G+ L                D     +C N   SY C C 
Sbjct: 116 GCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECL 174

Query: 201 EGYVAMPNGSQ 211
           EG+    +G +
Sbjct: 175 EGFRLAEDGKR 185



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 9/90 (10%)

Query: 3   GFNCTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC--YDSRKARCYG-- 57
           G  C   D C++    C++  C+N+  SYTC C   + L  DG  C   D  K+  +G  
Sbjct: 142 GKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCE 200

Query: 58  KVDLRSGTE---TCRDSDELSEDGTMAACC 84
            + + +G      C +   L+EDG     C
Sbjct: 201 HICVNNGNSYICKCSEGFVLAEDGRRCKKC 230


>X84700-1|CAA59173.1|  742|Homo sapiens leucocyte antigen CD97
           protein.
          Length = 742

 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 46/144 (31%), Positives = 67/144 (46%), Gaps = 22/144 (15%)

Query: 26  TQGSYTCR--CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAAC 83
           TQ S  C   CP N   V+  TAC  +     + ++ + + TETC   D+++E  T +  
Sbjct: 20  TQDSRGCARWCPQNSSCVN-ATACRCNPGFSSFSEI-ITTPTETC---DDINECATPSKV 74

Query: 84  CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV----TLADIDECAAHE 139
            C      G + D     GS  Y  +C   PGY+PV    ++      T  D+DEC++ +
Sbjct: 75  SC------GKFSDCWNTEGS--YDCVC--SPGYEPVSGAKTFKNESENTCQDVDECSSGQ 124

Query: 140 GLCAHGT-CTNTFGSFVCTCGAGW 162
             C   T C NT GS+ C C  GW
Sbjct: 125 HQCDSSTVCFNTVGSYSCRCRPGW 148



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 3/90 (3%)

Query: 2   PGFNCTDVDECKSPQ--SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           P   C D++EC +P   SC ++  C NT+GSY C C P YE VS      +  +  C   
Sbjct: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117

Query: 59  VDLRSGTETCRDSDELSEDGTMAACCCSVG 88
            +  SG   C  S          +C C  G
Sbjct: 118 DECSSGQHQCDSSTVCFNTVGSYSCRCRPG 147



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYE 39
           C DVDEC S Q  C     C NT GSY+CRC P ++
Sbjct: 114 CQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 149



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 35/119 (29%), Positives = 43/119 (36%), Gaps = 13/119 (10%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEP-PSYVVTLADIDECAAHEGL-CAH-GTCTNTFGSF 154
           CP+  S      C   PG+    E   +   T  DI+ECA    + C     C NT GS+
Sbjct: 30  CPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSY 89

Query: 155 VCTCGAGWSLAPXXXXXXXXXXXXRPDV--CGPG--------VCRNLPGSYVCLCPEGY 203
            C C  G+                  DV  C  G        VC N  GSY C C  G+
Sbjct: 90  DCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 148


>BC026690-1|AAH26690.1|  742|Homo sapiens CD97 molecule protein.
          Length = 742

 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 46/144 (31%), Positives = 67/144 (46%), Gaps = 22/144 (15%)

Query: 26  TQGSYTCR--CPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAAC 83
           TQ S  C   CP N   V+  TAC  +     + ++ + + TETC   D+++E  T +  
Sbjct: 20  TQDSRGCARWCPQNSSCVN-ATACRCNPGFSSFSEI-ITTPTETC---DDINECATPSKV 74

Query: 84  CCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYVV----TLADIDECAAHE 139
            C      G + D     GS  Y  +C   PGY+PV    ++      T  D+DEC++ +
Sbjct: 75  SC------GKFSDCWNTEGS--YDCVC--SPGYEPVSGAKTFKNESENTCQDVDECSSGQ 124

Query: 140 GLCAHGT-CTNTFGSFVCTCGAGW 162
             C   T C NT GS+ C C  GW
Sbjct: 125 HQCDSSTVCFNTVGSYSCRCRPGW 148



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 3/90 (3%)

Query: 2   PGFNCTDVDECKSPQ--SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGK 58
           P   C D++EC +P   SC ++  C NT+GSY C C P YE VS      +  +  C   
Sbjct: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117

Query: 59  VDLRSGTETCRDSDELSEDGTMAACCCSVG 88
            +  SG   C  S          +C C  G
Sbjct: 118 DECSSGQHQCDSSTVCFNTVGSYSCRCRPG 147



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 6   CTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYE 39
           C DVDEC S Q  C     C NT GSY+CRC P ++
Sbjct: 114 CQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 149



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 35/119 (29%), Positives = 43/119 (36%), Gaps = 13/119 (10%)

Query: 98  CPEPGSEAYRQLCPGGPGYQPVLEP-PSYVVTLADIDECAAHEGL-CAH-GTCTNTFGSF 154
           CP+  S      C   PG+    E   +   T  DI+ECA    + C     C NT GS+
Sbjct: 30  CPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSY 89

Query: 155 VCTCGAGWSLAPXXXXXXXXXXXXRPDV--CGPG--------VCRNLPGSYVCLCPEGY 203
            C C  G+                  DV  C  G        VC N  GSY C C  G+
Sbjct: 90  DCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 148


>AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive
           sequence DNA binding protein-1 protein.
          Length = 1008

 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 60/222 (27%), Positives = 85/222 (38%), Gaps = 43/222 (19%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C S      G C +  G Y C CPP +     G  C +   + C+    +  GT   R
Sbjct: 236 DSCASGPCHNGGTCFHYIGKYKCDCPPGFS----GRYC-EIAPSPCFRSPCVNGGTCEDR 290

Query: 70  DSDELS--EDGTMAACC-----CS----------------VGAAWGNYCDPCPEPGSEAY 106
           D+D     + G M   C     C                 +GAA    CD      + + 
Sbjct: 291 DTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAAALYACDRGYSLSAPSR 350

Query: 107 RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLA 165
            ++C     +    EPP  +    +IDEC +    C HG +C +    ++C C  G+  A
Sbjct: 351 IRVCQPHGVWS---EPPQCL----EIDECRSQP--CLHGGSCQDRVAGYLCLCSTGYEGA 401

Query: 166 PXXXXXXXXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGYVAM 206
                        R   C   G CRNLPG+YVC CP G+V +
Sbjct: 402 ----HCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGV 439



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 6/72 (8%)

Query: 133 DECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNL 191
           DEC AH   C +G +C N  G++VC C AG+                 P   G G C + 
Sbjct: 408 DECRAHP--CRNGGSCRNLPGAYVCRCPAGF--VGVHCETEVDACDSSPCQHG-GRCESG 462

Query: 192 PGSYVCLCPEGY 203
            G+Y+C+CPEG+
Sbjct: 463 GGAYLCVCPEGF 474



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 41/157 (26%), Positives = 55/157 (35%), Gaps = 20/157 (12%)

Query: 12  CKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDS 71
           C S      G C     SYTC CP  +     G  C  +R   C       SG   CR+ 
Sbjct: 160 CNSDPCFNGGSCDAHDDSYTCECPRGFH----GKHCEKARPHLC------SSG--PCRNG 207

Query: 72  DELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE-----PPSYV 126
               E G    C C      G +C+   +P S A      GG  +  + +     PP + 
Sbjct: 208 GTCKEAGGEYHCSCPYRFT-GRHCE-IGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFS 265

Query: 127 VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGW 162
               +I         C + GTC +    F C C AG+
Sbjct: 266 GRYCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGY 302



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 36/162 (22%), Positives = 52/162 (32%), Gaps = 18/162 (11%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C ++DEC+S      G C +    Y C C   YE    G  C +  +  C          
Sbjct: 366 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE----GAHC-ELERDEC--------RA 412

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQPVLE 121
             CR+            C C  G   G +C    D C     +   +   GG  Y  V  
Sbjct: 413 HPCRNGGSCRNLPGAYVCRCPAGFV-GVHCETEVDACDSSPCQHGGRCESGGGAYLCVCP 471

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS 163
              +      + +          G C  + GS  CTC  G++
Sbjct: 472 EGFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYT 513



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 31/115 (26%), Positives = 45/115 (39%), Gaps = 19/115 (16%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  + DEC++      G C N  G+Y CRCP  +  V             C  +VD 
Sbjct: 400 GAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGV------------HCETEVD- 446

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
              +  C+        G    C C  G  +G +C+   +P    +   C GG GY
Sbjct: 447 ACDSSPCQHGGRCESGGGAYLCVCPEG-FFGYHCETVSDP---CFSSPC-GGRGY 496



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 12/82 (14%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC------G 184
           D+D+C+    L   G+C +  G++ C C       P             PD C       
Sbjct: 2   DVDDCSPDPCLNG-GSCVDLVGNYTCLCAE-----PFKGLRCETGDHPVPDACLSAPCHN 55

Query: 185 PGVCRNLPGSYVCLCPEGYVAM 206
            G C +    YVC CPEG++ +
Sbjct: 56  GGTCVDADQGYVCECPEGFMGL 77



 Score = 33.1 bits (72), Expect = 0.83
 Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 2/28 (7%)

Query: 8  DVDECKSPQSC-QYGQCINTQGSYTCRC 34
          DVD+C SP  C   G C++  G+YTC C
Sbjct: 2  DVDDC-SPDPCLNGGSCVDLVGNYTCLC 28



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 33/131 (25%), Positives = 44/131 (33%), Gaps = 20/131 (15%)

Query: 83  CCCSVGAAWGNYCD---------PCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADID 133
           C CS G   G +C+         PC   GS      C   PG      P  +V    + +
Sbjct: 392 CLCSTGYE-GAHCELERDECRAHPCRNGGS------CRNLPGAYVCRCPAGFVGVHCETE 444

Query: 134 ECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLP 192
             A     C HG  C +  G+++C C  G+                     G G C    
Sbjct: 445 VDACDSSPCQHGGRCESGGGAYLCVCPEGFF---GYHCETVSDPCFSSPCGGRGYCLASN 501

Query: 193 GSYVCLCPEGY 203
           GS+ C C  GY
Sbjct: 502 GSHSCTCKVGY 512


>AK074396-1|BAB85069.1|  220|Homo sapiens protein ( Homo sapiens
          cDNA FLJ23816 fis, clone HSI02685. ).
          Length = 220

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 22/44 (50%), Positives = 27/44 (61%), Gaps = 1/44 (2%)

Query: 6  CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYD 49
          CTD+DEC+    CQ+  C NT+GSY C CP  Y L+  G  C D
Sbjct: 22 CTDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQD 64



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 34/95 (35%), Positives = 43/95 (45%), Gaps = 10/95 (10%)

Query: 122 PPSYVV---TLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
           PP ++       D+DEC     LC H  C NT GS+ C C AG+ L P            
Sbjct: 12  PPGFIRQNGVCTDLDECRVRN-LCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECE 69

Query: 179 RPDV-CGPG-VCRNLPGSYVCL---CPEGYVAMPN 208
              + CGPG +C N  GSY C+   CP  Y   P+
Sbjct: 70  EESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPS 104



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 5/51 (9%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQ-CINTQGSYTC---RCPPNYELVSDGTACY 48
           G NC D++EC+     C  GQ C NT+GSY C    CP  Y        C+
Sbjct: 59  GKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCF 109



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 14/22 (63%), Positives = 16/22 (72%)

Query: 188 CRNLPGSYVCLCPEGYVAMPNG 209
           CRN  GSY CLCP GY  +P+G
Sbjct: 38  CRNTEGSYQCLCPAGYRLLPSG 59


>BC077719-1|AAH77719.1|  219|Homo sapiens VWCE protein protein.
          Length = 219

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 21/48 (43%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDS 50
           G  CTD+DEC +  SC+ G C+NT+G + C C P  +L +D  +C D+
Sbjct: 137 GIRCTDIDECVT-SSCE-GHCVNTEGGFVCECGPGMQLSADRHSCQDT 182



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 41/131 (31%), Positives = 50/131 (38%), Gaps = 13/131 (9%)

Query: 76  EDGTMAACCCSVGAAWGNY-CD-PCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADID 133
           +DG   A C       G Y CD  C   G +   ++CP G      +   +  +   DID
Sbjct: 89  QDGEQGATCPETHGPCGEYGCDLTCNHGGCQEVARVCPVGFS----MTETAVGIRCTDID 144

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRPDVCGPGVCRNLP 192
           EC         G C NT G FVC CG G  L A              P  C    C+N  
Sbjct: 145 ECVTSS---CEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTP--CQQR-CKNSI 198

Query: 193 GSYVCLCPEGY 203
           GSY C C  G+
Sbjct: 199 GSYKCSCRTGF 209



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 2/43 (4%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           +C D DEC     CQ  +C N+ GSY C C   + L  +  +C
Sbjct: 178 SCQDTDECLGTP-CQQ-RCKNSIGSYKCSCRTGFHLHGNRHSC 218



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 7/56 (12%)

Query: 109 LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
           +C  GPG Q   +  S      D DEC    G      C N+ GS+ C+C  G+ L
Sbjct: 163 VCECGPGMQLSADRHS----CQDTDECL---GTPCQQRCKNSIGSYKCSCRTGFHL 211


>BC052564-1|AAH52564.1|  219|Homo sapiens VWCE protein protein.
          Length = 219

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 21/48 (43%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDS 50
           G  CTD+DEC +  SC+ G C+NT+G + C C P  +L +D  +C D+
Sbjct: 137 GIRCTDIDECVT-SSCE-GHCVNTEGGFVCECGPGMQLSADRHSCQDT 182



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 41/131 (31%), Positives = 50/131 (38%), Gaps = 13/131 (9%)

Query: 76  EDGTMAACCCSVGAAWGNY-CD-PCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADID 133
           +DG   A C       G Y CD  C   G +   ++CP G      +   +  +   DID
Sbjct: 89  QDGEQGATCPETHGPCGEYGCDLTCNHGGCQEVARVCPVGFS----MTETAVGIRCTDID 144

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRPDVCGPGVCRNLP 192
           EC         G C NT G FVC CG G  L A              P  C    C+N  
Sbjct: 145 ECVTSS---CEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTP--CQQR-CKNSI 198

Query: 193 GSYVCLCPEGY 203
           GSY C C  G+
Sbjct: 199 GSYKCSCRTGF 209



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 2/43 (4%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           +C D DEC     CQ  +C N+ GSY C C   + L  +  +C
Sbjct: 178 SCQDTDECLGTP-CQQ-RCKNSIGSYKCSCRTGFHLHGNRHSC 218



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 7/56 (12%)

Query: 109 LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
           +C  GPG Q   +  S      D DEC    G      C N+ GS+ C+C  G+ L
Sbjct: 163 VCECGPGMQLSADRHS----CQDTDECL---GTPCQQRCKNSIGSYKCSCRTGFHL 211


>BC042143-1|AAH42143.1|  237|Homo sapiens VWCE protein protein.
          Length = 237

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 21/48 (43%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDS 50
           G  CTD+DEC +  SC+ G C+NT+G + C C P  +L +D  +C D+
Sbjct: 155 GIRCTDIDECVT-SSCE-GHCVNTEGGFVCECGPGMQLSADRHSCQDT 200



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 41/131 (31%), Positives = 50/131 (38%), Gaps = 13/131 (9%)

Query: 76  EDGTMAACCCSVGAAWGNY-CD-PCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADID 133
           +DG   A C       G Y CD  C   G +   ++CP G      +   +  +   DID
Sbjct: 107 QDGEQGATCPETHGPCGEYGCDLTCNHGGCQEVARVCPVGFS----MTETAVGIRCTDID 162

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRPDVCGPGVCRNLP 192
           EC         G C NT G FVC CG G  L A              P  C    C+N  
Sbjct: 163 ECVTSS---CEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTP--CQQR-CKNSI 216

Query: 193 GSYVCLCPEGY 203
           GSY C C  G+
Sbjct: 217 GSYKCSCRTGF 227



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 2/43 (4%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           +C D DEC     CQ  +C N+ GSY C C   + L  +  +C
Sbjct: 196 SCQDTDECLGTP-CQQ-RCKNSIGSYKCSCRTGFHLHGNRHSC 236



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 7/56 (12%)

Query: 109 LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
           +C  GPG Q   +  S      D DEC    G      C N+ GS+ C+C  G+ L
Sbjct: 181 VCECGPGMQLSADRHS----CQDTDECL---GTPCQQRCKNSIGSYKCSCRTGFHL 229


>AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precursor
           protein.
          Length = 1406

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 56/209 (26%), Positives = 78/209 (37%), Gaps = 31/209 (14%)

Query: 8   DVDECKSP---QSCQ-YGQCINTQG--SYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           D D  K P     CQ    C+NT G  S+ C+CPP Y     GT C ++    C      
Sbjct: 66  DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY----SGTIC-ETTIGSC------ 114

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQ 117
             G  +C+      +D     C C  G A G +C    D C     +       G  GY 
Sbjct: 115 --GKNSCQHGGICHQDPIYPVCICPAGYA-GRFCEIDHDECASSPCQNGAVCQDGIDGYS 171

Query: 118 PVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P Y     D  +DECA+ +      TC N  G + C C   +S            
Sbjct: 172 -CFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEIGRYTCICPHNYS--GVNCELEIDE 227

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
              +P + G   C++  G+Y C C  G++
Sbjct: 228 CWSQPCLNG-ATCQDALGAYFCDCAPGFL 255



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 10/96 (10%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC  D+D C+S Q      CI+    Y+C C  N+     G  C   R++R    V  
Sbjct: 1208 GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNF----TGKFC---RQSRLPSTVCG 1260

Query: 62   RSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
               T  TC +    +E  T   C C  G   G +C+
Sbjct: 1261 NEKTNLTCYNGGNCTEFQTELKCMCRPGFT-GEWCE 1295



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVS 42
           G +C  +VDEC S        C+N  G YTC CP NY  V+
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVN 220



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 48/180 (26%), Positives = 72/180 (40%), Gaps = 31/180 (17%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYG 57
           PGF   +C  + DEC S      G C++ +  Y+C C  +      GT C ++    C+ 
Sbjct: 252 PGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGS---GFTGTHC-ETLMPLCWS 307

Query: 58  KVDLRSGTETCRDS-DELS----EDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQL 109
           K        TC DS D  +       T A C   +     N C     C E  SE     
Sbjct: 308 KP--CHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGR 365

Query: 110 CPGGP---------GYQPVLEPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTC 158
             G P         GY  + +P  + +    D++EC+++   C + GTC N  G++ C C
Sbjct: 366 ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHC 423



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCP 35
           G +C  DV+EC S      G C N  G+YTC CP
Sbjct: 391 GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 53/217 (24%), Positives = 71/217 (32%), Gaps = 29/217 (13%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  ++DEC S        C +  G+Y C C P +     G  C +     C  +  L
Sbjct: 218 GVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL----GDHC-ELNTDECASQPCL 272

Query: 62  RSGTETCRDSDE------LSEDGTMAACCCSVGAAWGNYC--DPCPEPGSEAYRQLC-PG 112
             G   C D +            T   C   +   W   C  +   E   + Y   C PG
Sbjct: 273 HGG--LCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPG 330

Query: 113 GPGYQPVLEPPSYVVTLADID-ECAAHEGLCAHGTCTNTFGSF--------VCTCGAGWS 163
             G Q  ++           + EC        +G  T    SF        VC C  G++
Sbjct: 331 YTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT 390

Query: 164 LAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
                           P   G G C NLPG+Y C CP
Sbjct: 391 --GIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHCP 424



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 142  CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
            C HG  C + + S+ C+C  GWS                P  C  G C +   +Y C C 
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCE 1203

Query: 201  EGYVAM 206
             GY  +
Sbjct: 1204 PGYTGV 1209



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 44/175 (25%), Positives = 66/175 (37%), Gaps = 31/175 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C  ++DEC S   C +G C +   +Y C C P Y  V+      + +  +C      
Sbjct: 1171 GKHCELNIDECFS-NPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQC------ 1223

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPG-- 115
             +   TC     +S   T    C   G   G +C     P    G+E     C  G    
Sbjct: 1224 -ANGATC-----ISH--TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275

Query: 116  -YQPVLE---PPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS 163
             +Q  L+    P +       DIDECA+    C + G C +    F C C   ++
Sbjct: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFA 1328



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 2/35 (5%)

Query: 6   CTDVDECKSPQSCQY-GQCINTQGSYTCRCPPNYE 39
           C   D C+S Q CQ  G+CIN   SY C C   YE
Sbjct: 670 CVRKDWCES-QPCQSRGRCINLWLSYQCDCHRPYE 703


>AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precursor
           protein.
          Length = 1376

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 56/209 (26%), Positives = 78/209 (37%), Gaps = 31/209 (14%)

Query: 8   DVDECKSP---QSCQ-YGQCINTQG--SYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           D D  K P     CQ    C+NT G  S+ C+CPP Y     GT C ++    C      
Sbjct: 66  DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY----SGTIC-ETTIGSC------ 114

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQ 117
             G  +C+      +D     C C  G A G +C    D C     +       G  GY 
Sbjct: 115 --GKNSCQHGGICHQDPIYPVCICPAGYA-GRFCEIDHDECASSPCQNGAVCQDGIDGYS 171

Query: 118 PVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P Y     D  +DECA+ +      TC N  G + C C   +S            
Sbjct: 172 -CFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEIGRYTCICPHNYS--GVNCELEIDE 227

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
              +P + G   C++  G+Y C C  G++
Sbjct: 228 CWSQPCLNG-ATCQDALGAYFCDCAPGFL 255



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 10/96 (10%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC  D+D C+S Q      CI+    Y+C C  N+     G  C   R++R    V  
Sbjct: 1208 GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNF----TGKFC---RQSRLPSTVCG 1260

Query: 62   RSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
               T  TC +    +E  T   C C  G   G +C+
Sbjct: 1261 NEKTNLTCYNGGNCTEFQTELKCMCRPGFT-GEWCE 1295



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVS 42
           G +C  +VDEC S        C+N  G YTC CP NY  V+
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVN 220



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 48/180 (26%), Positives = 72/180 (40%), Gaps = 31/180 (17%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYG 57
           PGF   +C  + DEC S      G C++ +  Y+C C  +      GT C ++    C+ 
Sbjct: 252 PGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGS---GFTGTHC-ETLMPLCWS 307

Query: 58  KVDLRSGTETCRDS-DELS----EDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQL 109
           K        TC DS D  +       T A C   +     N C     C E  SE     
Sbjct: 308 KP--CHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGR 365

Query: 110 CPGGP---------GYQPVLEPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTC 158
             G P         GY  + +P  + +    D++EC+++   C + GTC N  G++ C C
Sbjct: 366 ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHC 423



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCP 35
           G +C  DV+EC S      G C N  G+YTC CP
Sbjct: 391 GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 53/217 (24%), Positives = 71/217 (32%), Gaps = 29/217 (13%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  ++DEC S        C +  G+Y C C P +     G  C +     C  +  L
Sbjct: 218 GVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL----GDHC-ELNTDECASQPCL 272

Query: 62  RSGTETCRDSDE------LSEDGTMAACCCSVGAAWGNYC--DPCPEPGSEAYRQLC-PG 112
             G   C D +            T   C   +   W   C  +   E   + Y   C PG
Sbjct: 273 HGG--LCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPG 330

Query: 113 GPGYQPVLEPPSYVVTLADID-ECAAHEGLCAHGTCTNTFGSF--------VCTCGAGWS 163
             G Q  ++           + EC        +G  T    SF        VC C  G++
Sbjct: 331 YTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT 390

Query: 164 LAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
                           P   G G C NLPG+Y C CP
Sbjct: 391 --GIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHCP 424



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 142  CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
            C HG  C + + S+ C+C  GWS                P  C  G C +   +Y C C 
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCE 1203

Query: 201  EGYVAM 206
             GY  +
Sbjct: 1204 PGYTGV 1209



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 44/175 (25%), Positives = 66/175 (37%), Gaps = 31/175 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C  ++DEC S   C +G C +   +Y C C P Y  V+      + +  +C      
Sbjct: 1171 GKHCELNIDECFS-NPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQC------ 1223

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPG-- 115
             +   TC     +S   T    C   G   G +C     P    G+E     C  G    
Sbjct: 1224 -ANGATC-----ISH--TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275

Query: 116  -YQPVLE---PPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS 163
             +Q  L+    P +       DIDECA+    C + G C +    F C C   ++
Sbjct: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFA 1328



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 2/35 (5%)

Query: 6   CTDVDECKSPQSCQY-GQCINTQGSYTCRCPPNYE 39
           C   D C+S Q CQ  G+CIN   SY C C   YE
Sbjct: 670 CVRKDWCES-QPCQSRGRCINLWLSYQCDCHRPYE 703


>AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 1406

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 56/209 (26%), Positives = 78/209 (37%), Gaps = 31/209 (14%)

Query: 8   DVDECKSP---QSCQ-YGQCINTQG--SYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           D D  K P     CQ    C+NT G  S+ C+CPP Y     GT C ++    C      
Sbjct: 66  DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY----SGTIC-ETTIGSC------ 114

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQ 117
             G  +C+      +D     C C  G A G +C    D C     +       G  GY 
Sbjct: 115 --GKNSCQHGGICHQDPIYPVCICPAGYA-GRFCEIDHDECASSPCQNGAVCQDGIDGYS 171

Query: 118 PVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P Y     D  +DECA+ +      TC N  G + C C   +S            
Sbjct: 172 -CFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEIGRYTCICPHNYS--GVNCELEIDE 227

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
              +P + G   C++  G+Y C C  G++
Sbjct: 228 CWSQPCLNG-ATCQDALGAYFCDCAPGFL 255



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 10/96 (10%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC  D+D C+S Q      CI+    Y+C C  N+     G  C   R++R    V  
Sbjct: 1208 GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNF----TGKFC---RQSRLPSTVCG 1260

Query: 62   RSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
               T  TC +    +E  T   C C  G   G +C+
Sbjct: 1261 NEKTNLTCYNGGNCTEFQTELKCMCRPGFT-GEWCE 1295



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVS 42
           G +C  +VDEC S        C+N  G YTC CP NY  V+
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVN 220



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 48/180 (26%), Positives = 72/180 (40%), Gaps = 31/180 (17%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYG 57
           PGF   +C  + DEC S      G C++ +  Y+C C  +      GT C ++    C+ 
Sbjct: 252 PGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGS---GFTGTHC-ETLMPLCWS 307

Query: 58  KVDLRSGTETCRDS-DELS----EDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQL 109
           K        TC DS D  +       T A C   +     N C     C E  SE     
Sbjct: 308 KP--CHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGR 365

Query: 110 CPGGP---------GYQPVLEPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTC 158
             G P         GY  + +P  + +    D++EC+++   C + GTC N  G++ C C
Sbjct: 366 ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHC 423



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCP 35
           G +C  DV+EC S      G C N  G+YTC CP
Sbjct: 391 GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 53/217 (24%), Positives = 71/217 (32%), Gaps = 29/217 (13%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  ++DEC S        C +  G+Y C C P +     G  C +     C  +  L
Sbjct: 218 GVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL----GDHC-ELNTDECASQPCL 272

Query: 62  RSGTETCRDSDE------LSEDGTMAACCCSVGAAWGNYC--DPCPEPGSEAYRQLC-PG 112
             G   C D +            T   C   +   W   C  +   E   + Y   C PG
Sbjct: 273 HGG--LCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPG 330

Query: 113 GPGYQPVLEPPSYVVTLADID-ECAAHEGLCAHGTCTNTFGSF--------VCTCGAGWS 163
             G Q  ++           + EC        +G  T    SF        VC C  G++
Sbjct: 331 YTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT 390

Query: 164 LAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
                           P   G G C NLPG+Y C CP
Sbjct: 391 --GIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHCP 424



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 142  CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
            C HG  C + + S+ C+C  GWS                P  C  G C +   +Y C C 
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCE 1203

Query: 201  EGYVAM 206
             GY  +
Sbjct: 1204 PGYTGV 1209



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 44/175 (25%), Positives = 66/175 (37%), Gaps = 31/175 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C  ++DEC S   C +G C +   +Y C C P Y  V+      + +  +C      
Sbjct: 1171 GKHCELNIDECFS-NPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQC------ 1223

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPG-- 115
             +   TC     +S   T    C   G   G +C     P    G+E     C  G    
Sbjct: 1224 -ANGATC-----ISH--TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275

Query: 116  -YQPVLE---PPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS 163
             +Q  L+    P +       DIDECA+    C + G C +    F C C   ++
Sbjct: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFA 1328



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 2/35 (5%)

Query: 6   CTDVDECKSPQSCQY-GQCINTQGSYTCRCPPNYE 39
           C   D C+S Q CQ  G+CIN   SY C C   YE
Sbjct: 670 CVRKDWCES-QPCQSRGRCINLWLSYQCDCHRPYE 703


>AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 1406

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 56/209 (26%), Positives = 78/209 (37%), Gaps = 31/209 (14%)

Query: 8   DVDECKSP---QSCQ-YGQCINTQG--SYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           D D  K P     CQ    C+NT G  S+ C+CPP Y     GT C ++    C      
Sbjct: 66  DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY----SGTIC-ETTIGSC------ 114

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQ 117
             G  +C+      +D     C C  G A G +C    D C     +       G  GY 
Sbjct: 115 --GKNSCQHGGICHQDPIYPVCICPAGYA-GRFCEIDHDECASSPCQNGAVCQDGIDGYS 171

Query: 118 PVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P Y     D  +DECA+ +      TC N  G + C C   +S            
Sbjct: 172 -CFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEIGRYTCICPHNYS--GVNCELEIDE 227

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
              +P + G   C++  G+Y C C  G++
Sbjct: 228 CWSQPCLNG-ATCQDALGAYFCDCAPGFL 255



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 10/96 (10%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC  D+D C+S Q      CI+    Y+C C  N+     G  C   R++R    V  
Sbjct: 1208 GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNF----TGKFC---RQSRLPSTVCG 1260

Query: 62   RSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
               T  TC +    +E  T   C C  G   G +C+
Sbjct: 1261 NEKTNLTCYNGGNCTEFQTELKCMCRPGFT-GEWCE 1295



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVS 42
           G +C  +VDEC S        C+N  G YTC CP NY  V+
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVN 220



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 48/180 (26%), Positives = 72/180 (40%), Gaps = 31/180 (17%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYG 57
           PGF   +C  + DEC S      G C++ +  Y+C C  +      GT C ++    C+ 
Sbjct: 252 PGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGS---GFTGTHC-ETLMPLCWS 307

Query: 58  KVDLRSGTETCRDS-DELS----EDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQL 109
           K        TC DS D  +       T A C   +     N C     C E  SE     
Sbjct: 308 KP--CHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGR 365

Query: 110 CPGGP---------GYQPVLEPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTC 158
             G P         GY  + +P  + +    D++EC+++   C + GTC N  G++ C C
Sbjct: 366 ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHC 423



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCP 35
           G +C  DV+EC S      G C N  G+YTC CP
Sbjct: 391 GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 53/217 (24%), Positives = 71/217 (32%), Gaps = 29/217 (13%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  ++DEC S        C +  G+Y C C P +     G  C +     C  +  L
Sbjct: 218 GVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL----GDHC-ELNTDECASQPCL 272

Query: 62  RSGTETCRDSDE------LSEDGTMAACCCSVGAAWGNYC--DPCPEPGSEAYRQLC-PG 112
             G   C D +            T   C   +   W   C  +   E   + Y   C PG
Sbjct: 273 HGG--LCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPG 330

Query: 113 GPGYQPVLEPPSYVVTLADID-ECAAHEGLCAHGTCTNTFGSF--------VCTCGAGWS 163
             G Q  ++           + EC        +G  T    SF        VC C  G++
Sbjct: 331 YTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT 390

Query: 164 LAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
                           P   G G C NLPG+Y C CP
Sbjct: 391 --GIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHCP 424



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 142  CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
            C HG  C + + S+ C+C  GWS                P  C  G C +   +Y C C 
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCE 1203

Query: 201  EGYVAM 206
             GY  +
Sbjct: 1204 PGYTGV 1209



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 44/175 (25%), Positives = 66/175 (37%), Gaps = 31/175 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C  ++DEC S   C +G C +   +Y C C P Y  V+      + +  +C      
Sbjct: 1171 GKHCELNIDECFS-NPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQC------ 1223

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPG-- 115
             +   TC     +S   T    C   G   G +C     P    G+E     C  G    
Sbjct: 1224 -ANGATC-----ISH--TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275

Query: 116  -YQPVLE---PPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS 163
             +Q  L+    P +       DIDECA+    C + G C +    F C C   ++
Sbjct: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFA 1328



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 2/35 (5%)

Query: 6   CTDVDECKSPQSCQY-GQCINTQGSYTCRCPPNYE 39
           C   D C+S Q CQ  G+CIN   SY C C   YE
Sbjct: 670 CVRKDWCES-QPCQSRGRCINLWLSYQCDCHRPYE 703


>AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 1406

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 56/209 (26%), Positives = 78/209 (37%), Gaps = 31/209 (14%)

Query: 8   DVDECKSP---QSCQ-YGQCINTQG--SYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           D D  K P     CQ    C+NT G  S+ C+CPP Y     GT C ++    C      
Sbjct: 66  DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY----SGTIC-ETTIGSC------ 114

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQ 117
             G  +C+      +D     C C  G A G +C    D C     +       G  GY 
Sbjct: 115 --GKNSCQHGGICHQDPIYPVCICPAGYA-GRFCEIDHDECASSPCQNGAVCQDGIDGYS 171

Query: 118 PVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P Y     D  +DECA+ +      TC N  G + C C   +S            
Sbjct: 172 -CFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEIGRYTCICPHNYS--GVNCELEIDE 227

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
              +P + G   C++  G+Y C C  G++
Sbjct: 228 CWSQPCLNG-ATCQDALGAYFCDCAPGFL 255



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 10/96 (10%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC  D+D C+S Q      CI+    Y+C C  N+     G  C   R++R    V  
Sbjct: 1208 GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNF----TGKFC---RQSRLPSTVCG 1260

Query: 62   RSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
               T  TC +    +E  T   C C  G   G +C+
Sbjct: 1261 NEKTNLTCYNGGNCTEFQTELKCMCRPGFT-GEWCE 1295



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVS 42
           G +C  +VDEC S        C+N  G YTC CP NY  V+
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVN 220



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 48/180 (26%), Positives = 72/180 (40%), Gaps = 31/180 (17%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYG 57
           PGF   +C  + DEC S      G C++ +  Y+C C  +      GT C ++    C+ 
Sbjct: 252 PGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGS---GFTGTHC-ETLMPLCWS 307

Query: 58  KVDLRSGTETCRDS-DELS----EDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQL 109
           K        TC DS D  +       T A C   +     N C     C E  SE     
Sbjct: 308 KP--CHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGR 365

Query: 110 CPGGP---------GYQPVLEPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTC 158
             G P         GY  + +P  + +    D++EC+++   C + GTC N  G++ C C
Sbjct: 366 ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHC 423



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCP 35
           G +C  DV+EC S      G C N  G+YTC CP
Sbjct: 391 GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 53/217 (24%), Positives = 71/217 (32%), Gaps = 29/217 (13%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  ++DEC S        C +  G+Y C C P +     G  C +     C  +  L
Sbjct: 218 GVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL----GDHC-ELNTDECASQPCL 272

Query: 62  RSGTETCRDSDE------LSEDGTMAACCCSVGAAWGNYC--DPCPEPGSEAYRQLC-PG 112
             G   C D +            T   C   +   W   C  +   E   + Y   C PG
Sbjct: 273 HGG--LCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPG 330

Query: 113 GPGYQPVLEPPSYVVTLADID-ECAAHEGLCAHGTCTNTFGSF--------VCTCGAGWS 163
             G Q  ++           + EC        +G  T    SF        VC C  G++
Sbjct: 331 YTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT 390

Query: 164 LAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
                           P   G G C NLPG+Y C CP
Sbjct: 391 --GIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHCP 424



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 142  CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
            C HG  C + + S+ C+C  GWS                P  C  G C +   +Y C C 
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCE 1203

Query: 201  EGYVAM 206
             GY  +
Sbjct: 1204 PGYTGV 1209



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 44/175 (25%), Positives = 66/175 (37%), Gaps = 31/175 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C  ++DEC S   C +G C +   +Y C C P Y  V+      + +  +C      
Sbjct: 1171 GKHCELNIDECFS-NPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQC------ 1223

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPG-- 115
             +   TC     +S   T    C   G   G +C     P    G+E     C  G    
Sbjct: 1224 -ANGATC-----ISH--TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275

Query: 116  -YQPVLE---PPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS 163
             +Q  L+    P +       DIDECA+    C + G C +    F C C   ++
Sbjct: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFA 1328



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 2/35 (5%)

Query: 6   CTDVDECKSPQSCQY-GQCINTQGSYTCRCPPNYE 39
           C   D C+S Q CQ  G+CIN   SY C C   YE
Sbjct: 670 CVRKDWCES-QPCQSRGRCINLWLSYQCDCHRPYE 703


>AK056571-1|BAB71219.1|  955|Homo sapiens protein ( Homo sapiens
           cDNA FLJ32009 fis, clone NT2RP7009498, weakly similar to
           FIBULIN-1, ISOFORM A PRECURSOR. ).
          Length = 955

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 21/48 (43%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDS 50
           G  CTD+DEC +  SC+ G C+NT+G + C C P  +L +D  +C D+
Sbjct: 137 GIRCTDIDECVT-SSCE-GHCVNTEGGFVCECGPGMQLSADRHSCQDT 182



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 41/131 (31%), Positives = 50/131 (38%), Gaps = 13/131 (9%)

Query: 76  EDGTMAACCCSVGAAWGNY-CD-PCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADID 133
           +DG   A C       G Y CD  C   G +   ++CP G      +   +  +   DID
Sbjct: 89  QDGEQGATCPETHGPCGEYGCDLTCNHGGCQEVARVCPVGFS----MTEAAVGIRCTDID 144

Query: 134 ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL-APXXXXXXXXXXXXRPDVCGPGVCRNLP 192
           EC         G C NT G FVC CG G  L A              P  C    C+N  
Sbjct: 145 ECVTSS---CEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTP--CQQR-CKNSI 198

Query: 193 GSYVCLCPEGY 203
           GSY C C  G+
Sbjct: 199 GSYKCSCRTGF 209



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 4/52 (7%)

Query: 5   NCTDVDECKSP---QSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKA 53
           +C DV+EC+ P   + C +  C NT GS+ C C P + L +D  +C    KA
Sbjct: 217 SCVDVNECRRPLERRVCHHS-CHNTVGSFLCTCRPGFRLRADRVSCEAFPKA 267



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 11/98 (11%)

Query: 109 LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXX 168
           +C  GPG Q   +  S      D DEC    G      C N+ GS+ C+C  G+ L    
Sbjct: 163 VCECGPGMQLSADRHS----CQDTDECL---GTPCQQRCKNSIGSYKCSCRTGFHLHGNR 215

Query: 169 XXXXXXXXXXRP---DVCGPGVCRNLPGSYVCLCPEGY 203
                     RP    VC    C N  GS++C C  G+
Sbjct: 216 HSCVDVNECRRPLERRVCHHS-CHNTVGSFLCTCRPGF 252



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 2/50 (4%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKAR 54
           +C D DEC     CQ  +C N+ GSY C C   + L  +  +C D  + R
Sbjct: 178 SCQDTDECLGTP-CQQ-RCKNSIGSYKCSCRTGFHLHGNRHSCVDVNECR 225



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 1/35 (2%)

Query: 131 DIDECAAH-EGLCAHGTCTNTFGSFVCTCGAGWSL 164
           D++EC    E    H +C NT GSF+CTC  G+ L
Sbjct: 220 DVNECRRPLERRVCHHSCHNTVGSFLCTCRPGFRL 254


>AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.
          Length = 1376

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 56/209 (26%), Positives = 78/209 (37%), Gaps = 31/209 (14%)

Query: 8   DVDECKSP---QSCQ-YGQCINTQG--SYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           D D  K P     CQ    C+NT G  S+ C+CPP Y     GT C ++    C      
Sbjct: 66  DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY----SGTIC-ETTIGSC------ 114

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQ 117
             G  +C+      +D     C C  G A G +C    D C     +       G  GY 
Sbjct: 115 --GKNSCQHGGICHQDPIYPVCICPAGYA-GRFCEIDHDECASSPCQNGAVCQDGIDGYS 171

Query: 118 PVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P Y     D  +DECA+ +      TC N  G + C C   +S            
Sbjct: 172 -CFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEIGRYTCICPHNYS--GVNCELEIDE 227

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
              +P + G   C++  G+Y C C  G++
Sbjct: 228 CWSQPCLNG-ATCQDALGAYFCDCAPGFL 255



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 10/96 (10%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC  D+D C+S Q      CI+    Y+C C  N+     G  C   R++R    V  
Sbjct: 1208 GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNF----TGKFC---RQSRLPSTVCG 1260

Query: 62   RSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
               T  TC +    +E  T   C C  G   G +C+
Sbjct: 1261 NEKTNLTCYNGGNCTEFQTELKCMCRPGFT-GEWCE 1295



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVS 42
           G +C  +VDEC S        C+N  G YTC CP NY  V+
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVN 220



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 48/180 (26%), Positives = 72/180 (40%), Gaps = 31/180 (17%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYG 57
           PGF   +C  + DEC S      G C++ +  Y+C C  +      GT C ++    C+ 
Sbjct: 252 PGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGS---GFTGTHC-ETLMPLCWS 307

Query: 58  KVDLRSGTETCRDS-DELS----EDGTMAACCCSVGAAWGNYCD---PCPEPGSEAYRQL 109
           K        TC DS D  +       T A C   +     N C     C E  SE     
Sbjct: 308 KP--CHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGR 365

Query: 110 CPGGP---------GYQPVLEPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTC 158
             G P         GY  + +P  + +    D++EC+++   C + GTC N  G++ C C
Sbjct: 366 ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHC 423



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCP 35
           G +C  DV+EC S      G C N  G+YTC CP
Sbjct: 391 GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 53/217 (24%), Positives = 71/217 (32%), Gaps = 29/217 (13%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G NC  ++DEC S        C +  G+Y C C P +     G  C +     C  +  L
Sbjct: 218 GVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL----GDHC-ELNTDECASQPCL 272

Query: 62  RSGTETCRDSDE------LSEDGTMAACCCSVGAAWGNYC--DPCPEPGSEAYRQLC-PG 112
             G   C D +            T   C   +   W   C  +   E   + Y   C PG
Sbjct: 273 HGG--LCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPG 330

Query: 113 GPGYQPVLEPPSYVVTLADID-ECAAHEGLCAHGTCTNTFGSF--------VCTCGAGWS 163
             G Q  ++           + EC        +G  T    SF        VC C  G++
Sbjct: 331 YTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT 390

Query: 164 LAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
                           P   G G C NLPG+Y C CP
Sbjct: 391 --GIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHCP 424



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 142  CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
            C HG  C + + S+ C+C  GWS                P  C  G C +   +Y C C 
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCE 1203

Query: 201  EGYVAM 206
             GY  +
Sbjct: 1204 PGYTGV 1209



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 44/175 (25%), Positives = 66/175 (37%), Gaps = 31/175 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C  ++DEC S   C +G C +   +Y C C P Y  V+      + +  +C      
Sbjct: 1171 GKHCELNIDECFS-NPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQC------ 1223

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPG-- 115
             +   TC     +S   T    C   G   G +C     P    G+E     C  G    
Sbjct: 1224 -ANGATC-----ISH--TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275

Query: 116  -YQPVLE---PPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS 163
             +Q  L+    P +       DIDECA+    C + G C +    F C C   ++
Sbjct: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFA 1328



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 2/35 (5%)

Query: 6   CTDVDECKSPQSCQY-GQCINTQGSYTCRCPPNYE 39
           C   D C+S Q CQ  G+CIN   SY C C   YE
Sbjct: 670 CVRKDWCES-QPCQSRGRCINLWLSYQCDCHRPYE 703


>AB208923-1|BAD92160.1|  441|Homo sapiens crumbs homolog 1 isoform
           II precursor variant protein.
          Length = 441

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 56/209 (26%), Positives = 78/209 (37%), Gaps = 31/209 (14%)

Query: 8   DVDECKSP---QSCQ-YGQCINTQG--SYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           D D  K P     CQ    C+NT G  S+ C+CPP Y     GT C ++    C      
Sbjct: 91  DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY----SGTIC-ETTIGSC------ 139

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQ 117
             G  +C+      +D     C C  G A G +C    D C     +       G  GY 
Sbjct: 140 --GKNSCQHGGICHQDPIYPVCICPAGYA-GRFCEIDHDECASSPCQNGAVCQDGIDGYS 196

Query: 118 PVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
                P Y     D  +DECA+ +      TC N  G + C C   +S            
Sbjct: 197 -CFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEIGRYTCICPHNYS--GVNCELEIDE 252

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
              +P + G   C++  G+Y C C  G++
Sbjct: 253 CWSQPCLNG-ATCQDALGAYFCDCAPGFL 280



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVS 42
           G +C  +VDEC S        C+N  G YTC CP NY  V+
Sbjct: 205 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVN 245



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 13/37 (35%), Positives = 18/37 (48%), Gaps = 1/37 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY 38
           G NC  ++DEC S        C +  G+Y C C P +
Sbjct: 243 GVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGF 279


>AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.
          Length = 1282

 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 62/224 (27%), Positives = 80/224 (35%), Gaps = 47/224 (20%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           D C S      G C +  G Y C CPP +     G  C +   + C+    +  GT  C 
Sbjct: 490 DSCASGPCHNGGTCFHYIGKYKCDCPPGFS----GRHC-EIAPSPCFRSPCVNGGT--CE 542

Query: 70  DSDELSEDGTMAACCCSVGAAWGNYCDP---CPEPGSEAYRQL--------------CPG 112
           D D      T   C C  G   G  C     C  P    +  L              C  
Sbjct: 543 DRD------TDFFCHCQAGYM-GRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDR 595

Query: 113 G-----PGYQPVLEPP---SYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWS 163
           G     P    V +P    S      +IDEC +    C HG +C +    ++C C  G+ 
Sbjct: 596 GYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQP--CLHGGSCQDRVAGYLCLCSTGYE 653

Query: 164 LAPXXXXXXXXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGYVAM 206
            A             R   C   G CRNLPG+YVC CP G+V +
Sbjct: 654 GA----HCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGV 693



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 6/72 (8%)

Query: 133 DECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNL 191
           DEC AH   C +G +C N  G++VC C AG+                 P   G G C + 
Sbjct: 662 DECRAHP--CRNGGSCRNLPGAYVCRCPAGF--VGVHCETEVDACDSSPCQHG-GRCESG 716

Query: 192 PGSYVCLCPEGY 203
            G+Y+C+CPE +
Sbjct: 717 GGAYLCVCPESF 728



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 36/162 (22%), Positives = 52/162 (32%), Gaps = 18/162 (11%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C ++DEC+S      G C +    Y C C   YE    G  C +  +  C          
Sbjct: 620 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE----GAHC-ELERDEC--------RA 666

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQPVLE 121
             CR+            C C  G   G +C    D C     +   +   GG  Y  V  
Sbjct: 667 HPCRNGGSCRNLPGAYVCRCPAGFV-GVHCETEVDACDSSPCQHGGRCESGGGAYLCVCP 725

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS 163
              +      + +          G C  + GS  CTC  G++
Sbjct: 726 ESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYT 767



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 47/212 (22%), Positives = 71/212 (33%), Gaps = 32/212 (15%)

Query: 6   CTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           C  +  C +   C    C+    SYTC C      +S  T        RC+  V+    +
Sbjct: 141 CLALRPCLNGGKC-IDDCVTGNPSYTCSC------LSGFTG------RRCHLDVN-ECAS 186

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQ---LCPGGPGYQPVLEP 122
           + C++    +       C C  G   G  C+    P      Q    C    G    +  
Sbjct: 187 QPCQNGGTCTHGINSFRCQCPAGFG-GPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQ 245

Query: 123 PSYVVTLA--DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
             Y       D+D+C+    L   G+C +  G++ C C       P             P
Sbjct: 246 AGYTGAACEMDVDDCSPDPCLNG-GSCVDLVGNYTCLCAE-----PFKGLRCETGDHPVP 299

Query: 181 DVC------GPGVCRNLPGSYVCLCPEGYVAM 206
           D C        G C +    YVC CPEG++ +
Sbjct: 300 DACLSAPCHNGGTCVDADQGYVCECPEGFMGL 331



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 41/157 (26%), Positives = 55/157 (35%), Gaps = 20/157 (12%)

Query: 12  CKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDS 71
           C S      G C     SYTC CP  +     G  C  +R   C       SG   CR+ 
Sbjct: 414 CDSDPCFNGGSCDAHDDSYTCECPRGFH----GKHCEKARPHLC------SSG--PCRNG 461

Query: 72  DELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE-----PPSYV 126
               E G    C C      G +C+   +P S A      GG  +  + +     PP + 
Sbjct: 462 GTCKEAGGEYHCSCPYRFT-GRHCE-IGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFS 519

Query: 127 VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGW 162
               +I         C + GTC +    F C C AG+
Sbjct: 520 GRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGY 556



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 5/70 (7%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELV---SDGTACYDSRKARCYGK 58
           G +C  + DEC++      G C N  G+Y CRCP  +  V   ++  AC DS   +  G+
Sbjct: 654 GAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDAC-DSSPCQHGGR 712

Query: 59  VDLRSGTETC 68
            +   G   C
Sbjct: 713 CESGGGAYLC 722



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 35/132 (26%), Positives = 45/132 (34%), Gaps = 22/132 (16%)

Query: 83  CCCSVGAAWGNYCD---------PCPEPGSEAYRQLCPGGPGYQPVLEPPSYVVTLADID 133
           C CS G   G +C+         PC   GS      C   PG      P  +V    + +
Sbjct: 646 CLCSTGYE-GAHCELERDECRAHPCRNGGS------CRNLPGAYVCRCPAGFVGVHCETE 698

Query: 134 ECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGP-GVCRNL 191
             A     C HG  C +  G+++C C    S                P  CG  G C   
Sbjct: 699 VDACDSSPCQHGGRCESGGGAYLCVCPE--SFFGYHCETVSDPCFSSP--CGGRGYCLAS 754

Query: 192 PGSYVCLCPEGY 203
            GS+ C C  GY
Sbjct: 755 NGSHSCTCKVGY 766


>X12892-1|CAA31383.1|  650|Homo sapiens protein ( H.sapiens mRNA for
           protein S. ).
          Length = 650

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 28/77 (36%), Positives = 40/77 (51%), Gaps = 5/77 (6%)

Query: 131 DIDEC---AAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCGPG 186
           DI+EC   +   G C+   C NT GS+ C+C  G+  L+             +P +CG  
Sbjct: 131 DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 189

Query: 187 VCRNLPGSYVCLCPEGY 203
           VC+N+ G + C CPEGY
Sbjct: 190 VCKNILGDFECECPEGY 206



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 33/144 (22%), Positives = 51/144 (35%), Gaps = 14/144 (9%)

Query: 68  CRDSDELSEDGTMAACCCSVGAAW-GNYCD----PCPEPGS--EAYRQLCPGGPGYQPVL 120
           C +   +S     A+  C+    W G  C+     C +P +      Q+C   PG     
Sbjct: 100 CNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCS 159

Query: 121 EPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               +V+        D+DEC+    +C    C N  G F C C  G+             
Sbjct: 160 CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDID 219

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLC 199
                ++C   +C N PG + C C
Sbjct: 220 ECSE-NMCAQ-LCVNYPGGHTCYC 241



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 19/63 (30%), Positives = 25/63 (39%)

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
           +C +   SF CTC  GW                  +     +C N PGSY C C  G+V 
Sbjct: 107 SCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 166

Query: 206 MPN 208
           + N
Sbjct: 167 LSN 169



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 15/114 (13%)

Query: 8   DVDECKSPQSCQYGQ---CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           D++ECK P +   G    C NT GSY C C   + ++S+   C D  +  C  K  +  G
Sbjct: 131 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDE--CSLKPSI-CG 187

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLCPGGPG 115
           T  C++   L +      C C  G  +      C+   E       QLC   PG
Sbjct: 188 TAVCKNI--LGD----FECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPG 235



 Score = 34.7 bits (76), Expect = 0.27
 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 4/45 (8%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRC--PPNYELVSDGTAC 47
           +C D+DEC      Q   C+N  G +TC C     ++L  D  +C
Sbjct: 214 SCEDIDECSENMCAQL--CVNYPGGHTCYCDGKKGFKLAQDQKSC 256


>M17778-1|AAA36799.1|  640|Homo sapiens protein ( Human uromodulin
           (Tamm-Horsfall glycoprotein) mRNA, complete cds. ).
          Length = 640

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 32/83 (38%), Positives = 42/83 (50%), Gaps = 8/83 (9%)

Query: 127 VTLADIDECA---AHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV- 182
           +T  D+DECA   AH    A+ +C NT GSF C C  G+ L+P             P + 
Sbjct: 61  LTCVDLDECAIPGAHN-CSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECA-EPGLS 118

Query: 183 -CGP-GVCRNLPGSYVCLCPEGY 203
            C     C N+ GSY+C+CP GY
Sbjct: 119 HCHALATCVNVVGSYLCVCPAGY 141



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/49 (46%), Positives = 24/49 (48%), Gaps = 5/49 (10%)

Query: 2   PGFNCTDVDECKSP--QSCQ-YGQCINTQGSYTCRCPPNYELVSDGTAC 47
           PG  CTDVDEC  P    C     C+N  GSY C CP  Y    DG  C
Sbjct: 102 PGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYR--GDGWHC 148



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 50/168 (29%), Positives = 65/168 (38%), Gaps = 33/168 (19%)

Query: 3   GFNCTDVDECKSP--QSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           G  C D+DEC  P   +C     C+NT GS++C CP  + L S G  C D          
Sbjct: 60  GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL-SPGLGCTD---------- 108

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQLCPG--GPG 115
                 + C +   LS    +A C   V    G+Y   CP    G   + +  PG  GPG
Sbjct: 109 -----VDECAEPG-LSHCHALATCVNVV----GSYLCVCPAGYRGDGWHCECSPGSCGPG 158

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVC-TCGAGW 162
              V E  + V      D C AH  L  +   T     + C T   GW
Sbjct: 159 LDCVPEGDALVCA----DPCQAHRTLDEYWRSTEYGEGYACDTDLRGW 202



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 25/87 (28%), Positives = 32/87 (36%), Gaps = 3/87 (3%)

Query: 124 SYVVTLADIDECAAHEGLCAHG--TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
           S+ +T A  D   A      H   TCT       CTC  G++                  
Sbjct: 16  SWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAH 75

Query: 182 VCGPGV-CRNLPGSYVCLCPEGYVAMP 207
            C     C N PGS+ C+CPEG+   P
Sbjct: 76  NCSANSSCVNTPGSFSCVCPEGFRLSP 102


>M15881-1|AAA36798.1|  640|Homo sapiens protein ( Human uromodulin
           (Tamm-Horsfall glycoprotein) mRNA, complete cds. ).
          Length = 640

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 32/83 (38%), Positives = 42/83 (50%), Gaps = 8/83 (9%)

Query: 127 VTLADIDECA---AHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV- 182
           +T  D+DECA   AH    A+ +C NT GSF C C  G+ L+P             P + 
Sbjct: 61  LTCVDLDECAIPGAHN-CSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECA-EPGLS 118

Query: 183 -CGP-GVCRNLPGSYVCLCPEGY 203
            C     C N+ GSY+C+CP GY
Sbjct: 119 HCHALATCVNVVGSYLCVCPAGY 141



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/49 (46%), Positives = 24/49 (48%), Gaps = 5/49 (10%)

Query: 2   PGFNCTDVDECKSP--QSCQ-YGQCINTQGSYTCRCPPNYELVSDGTAC 47
           PG  CTDVDEC  P    C     C+N  GSY C CP  Y    DG  C
Sbjct: 102 PGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYR--GDGWHC 148



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 50/168 (29%), Positives = 65/168 (38%), Gaps = 33/168 (19%)

Query: 3   GFNCTDVDECKSP--QSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           G  C D+DEC  P   +C     C+NT GS++C CP  + L S G  C D          
Sbjct: 60  GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL-SPGLGCTD---------- 108

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQLCPG--GPG 115
                 + C +   LS    +A C   V    G+Y   CP    G   + +  PG  GPG
Sbjct: 109 -----VDECAEPG-LSHCHALATCVNVV----GSYLCVCPAGYRGDGWHCECSPGSCGPG 158

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVC-TCGAGW 162
              V E  + V      D C AH  L  +   T     + C T   GW
Sbjct: 159 LDCVPEGDALVCA----DPCQAHRTLDEYWRSTEYGEGYACDTDLRGW 202



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 25/87 (28%), Positives = 32/87 (36%), Gaps = 3/87 (3%)

Query: 124 SYVVTLADIDECAAHEGLCAHG--TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
           S+ +T A  D   A      H   TCT       CTC  G++                  
Sbjct: 16  SWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAH 75

Query: 182 VCGPGV-CRNLPGSYVCLCPEGYVAMP 207
            C     C N PGS+ C+CPEG+   P
Sbjct: 76  NCSANSSCVNTPGSFSCVCPEGFRLSP 102


>M14338-1|AAA60181.1|  650|Homo sapiens protein S precursor protein.
          Length = 650

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 28/77 (36%), Positives = 40/77 (51%), Gaps = 5/77 (6%)

Query: 131 DIDEC---AAHEGLCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCGPG 186
           DI+EC   +   G C+   C NT GS+ C+C  G+  L+             +P +CG  
Sbjct: 131 DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 189

Query: 187 VCRNLPGSYVCLCPEGY 203
           VC+N+ G + C CPEGY
Sbjct: 190 VCKNILGDFECECPEGY 206



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 33/144 (22%), Positives = 51/144 (35%), Gaps = 14/144 (9%)

Query: 68  CRDSDELSEDGTMAACCCSVGAAW-GNYCD----PCPEPGS--EAYRQLCPGGPGYQPVL 120
           C +   +S     A+  C+    W G  C+     C +P +      Q+C   PG     
Sbjct: 100 CNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCS 159

Query: 121 EPPSYVVT-----LADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXX 175
               +V+        D+DEC+    +C    C N  G F C C  G+             
Sbjct: 160 CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDID 219

Query: 176 XXXRPDVCGPGVCRNLPGSYVCLC 199
                ++C   +C N PG + C C
Sbjct: 220 ECSE-NMCAQ-LCVNYPGGHTCYC 241



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 19/63 (30%), Positives = 25/63 (39%)

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYVA 205
           +C +   SF CTC  GW                  +     +C N PGSY C C  G+V 
Sbjct: 107 SCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 166

Query: 206 MPN 208
           + N
Sbjct: 167 LSN 169



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 15/114 (13%)

Query: 8   DVDECKSPQSCQYGQ---CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           D++ECK P +   G    C NT GSY C C   + ++S+   C D  +  C  K  +  G
Sbjct: 131 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDE--CSLKPSI-CG 187

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLCPGGPG 115
           T  C++   L +      C C  G  +      C+   E       QLC   PG
Sbjct: 188 TAVCKNI--LGD----FECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPG 235



 Score = 34.7 bits (76), Expect = 0.27
 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 4/45 (8%)

Query: 5   NCTDVDECKSPQSCQYGQCINTQGSYTCRC--PPNYELVSDGTAC 47
           +C D+DEC      Q   C+N  G +TC C     ++L  D  +C
Sbjct: 214 SCEDIDECSENMCAQL--CVNYPGGHTCYCDGKKGFKLAQDQKSC 256


>BC035975-1|AAH35975.1|  611|Homo sapiens UMOD protein protein.
          Length = 611

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 32/83 (38%), Positives = 42/83 (50%), Gaps = 8/83 (9%)

Query: 127 VTLADIDECA---AHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV- 182
           +T  D+DECA   AH    A+ +C NT GSF C C  G+ L+P             P + 
Sbjct: 61  LTCVDLDECAIPGAHN-CSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECA-EPGLS 118

Query: 183 -CGP-GVCRNLPGSYVCLCPEGY 203
            C     C N+ GSY+C+CP GY
Sbjct: 119 HCHALATCVNVVGSYLCVCPAGY 141



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/49 (46%), Positives = 24/49 (48%), Gaps = 5/49 (10%)

Query: 2   PGFNCTDVDECKSP--QSCQ-YGQCINTQGSYTCRCPPNYELVSDGTAC 47
           PG  CTDVDEC  P    C     C+N  GSY C CP  Y    DG  C
Sbjct: 102 PGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYR--GDGWHC 148



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 50/168 (29%), Positives = 65/168 (38%), Gaps = 33/168 (19%)

Query: 3   GFNCTDVDECKSP--QSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           G  C D+DEC  P   +C     C+NT GS++C CP  + L S G  C D          
Sbjct: 60  GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL-SPGLGCTD---------- 108

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQLCPG--GPG 115
                 + C +   LS    +A C   V    G+Y   CP    G   + +  PG  GPG
Sbjct: 109 -----VDECAEPG-LSHCHALATCVNVV----GSYLCVCPAGYRGDGWHCECSPGSCGPG 158

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVC-TCGAGW 162
              V E  + V      D C AH  L  +   T     + C T   GW
Sbjct: 159 LDCVPEGDALVCA----DPCQAHRTLDEYWRSTEYGEGYACDTDLRGW 202



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 25/87 (28%), Positives = 32/87 (36%), Gaps = 3/87 (3%)

Query: 124 SYVVTLADIDECAAHEGLCAHG--TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
           S+ +T A  D   A      H   TCT       CTC  G++                  
Sbjct: 16  SWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAH 75

Query: 182 VCGPGV-CRNLPGSYVCLCPEGYVAMP 207
            C     C N PGS+ C+CPEG+   P
Sbjct: 76  NCSANSSCVNTPGSFSCVCPEGFRLSP 102


>AY162970-1|AAO64446.1|  640|Homo sapiens uromodulin precursor
           protein.
          Length = 640

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 32/83 (38%), Positives = 42/83 (50%), Gaps = 8/83 (9%)

Query: 127 VTLADIDECA---AHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV- 182
           +T  D+DECA   AH    A+ +C NT GSF C C  G+ L+P             P + 
Sbjct: 61  LTCVDLDECAIPGAHN-CSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECA-EPGLS 118

Query: 183 -CGP-GVCRNLPGSYVCLCPEGY 203
            C     C N+ GSY+C+CP GY
Sbjct: 119 HCHALATCVNVVGSYLCVCPAGY 141



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/49 (46%), Positives = 24/49 (48%), Gaps = 5/49 (10%)

Query: 2   PGFNCTDVDECKSP--QSCQ-YGQCINTQGSYTCRCPPNYELVSDGTAC 47
           PG  CTDVDEC  P    C     C+N  GSY C CP  Y    DG  C
Sbjct: 102 PGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYR--GDGWHC 148



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 50/168 (29%), Positives = 65/168 (38%), Gaps = 33/168 (19%)

Query: 3   GFNCTDVDECKSP--QSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           G  C D+DEC  P   +C     C+NT GS++C CP  + L S G  C D          
Sbjct: 60  GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL-SPGLGCTD---------- 108

Query: 60  DLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPE--PGSEAYRQLCPG--GPG 115
                 + C +   LS    +A C   V    G+Y   CP    G   + +  PG  GPG
Sbjct: 109 -----VDECAEPG-LSHCHALATCVNVV----GSYLCVCPAGYRGDGWHCECSPGSCGPG 158

Query: 116 YQPVLEPPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVC-TCGAGW 162
              V E  + V      D C AH  L  +   T     + C T   GW
Sbjct: 159 LDCVPEGDALVCA----DPCQAHRTLDEYWRSTEYGEGYACDTDLRGW 202



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 25/87 (28%), Positives = 32/87 (36%), Gaps = 3/87 (3%)

Query: 124 SYVVTLADIDECAAHEGLCAHG--TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
           S+ +T A  D   A      H   TCT       CTC  G++                  
Sbjct: 16  SWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAH 75

Query: 182 VCGPGV-CRNLPGSYVCLCPEGYVAMP 207
            C     C N PGS+ C+CPEG+   P
Sbjct: 76  NCSANSSCVNTPGSFSCVCPEGFRLSP 102


>D83017-1|BAA11680.1|  810|Homo sapiens nel-related protein protein.
          Length = 810

 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 53/209 (25%), Positives = 72/209 (34%), Gaps = 25/209 (11%)

Query: 6   CTDVDECKSPQSCQYGQ--CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           C D+DEC +     +    C+N  G Y C C P Y  V D +         C    +  S
Sbjct: 432 CEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFS---------CTEHDECGS 482

Query: 64  GTETCRDSDELSEDGTMAACCCSVG-AAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
           G   C ++   +      +C C  G    G  C    E G   Y   C         + P
Sbjct: 483 GQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCR-YGGTCVAP---NKCVCP 538

Query: 123 PSYVVTLA--DIDECAAHEGLC-AHGTCTNTFGSFVCTCGAG------WSLAPXXXXXXX 173
             +  +    DIDEC+     C  H  C N  G + C C +G      +SL+        
Sbjct: 539 SGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDID 598

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                         C NL G + CLCP G
Sbjct: 599 ECALRTHTCWNDSACINLAGGFDCLCPSG 627



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 52/175 (29%), Positives = 73/175 (41%), Gaps = 36/175 (20%)

Query: 4   FNCTDVDECKSPQ-SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           F+CT+ DEC S Q +C +   C NT   ++C C P Y  V +GT C      R + +   
Sbjct: 472 FSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY--VGNGTIC------RAFCEEGC 523

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAY-RQLCPGGPGY 116
           R G  TC   ++         C C  G   G++C    D C E   E +    C   PG+
Sbjct: 524 RYG-GTCVAPNK---------CVCPSGFT-GSHCEKDIDECSEGIIECHNHSRCVNLPGW 572

Query: 117 ------QPVLEPPSYVV---TLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAG 161
                     +  +Y +   +  DIDECA     C +   C N  G F C C +G
Sbjct: 573 YHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 42/180 (23%), Positives = 63/180 (35%), Gaps = 12/180 (6%)

Query: 33  RCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWG 92
           +C    +++++G          C G V ++  TE C   +   +D  +    C       
Sbjct: 334 KCIYGGKVLAEGQRILTKSCRECRGGVLVKI-TEMCPPLNCSEKDHILPENQCCRVCRGH 392

Query: 93  NYCDPCPEPGSEAY------RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHG 145
           N+C   P+ G  +       +  C    GY  V    +Y     DIDECAA    C A+ 
Sbjct: 393 NFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYC---EDIDECAAKMHYCHANT 449

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEGYV 204
            C N  G + C C  G+                    C    +C N    + C C  GYV
Sbjct: 450 VCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV 509



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 1   MPGFNCTDVDECK-SPQSC-QYGQCINTQGSYTCRCP 35
           + G +C D+DEC     +C     CIN  G + C CP
Sbjct: 589 LSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCP 625


>BC096102-1|AAH96102.1|  810|Homo sapiens NEL-like 1 (chicken)
           protein.
          Length = 810

 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 53/209 (25%), Positives = 72/209 (34%), Gaps = 25/209 (11%)

Query: 6   CTDVDECKSPQSCQYGQ--CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           C D+DEC +     +    C+N  G Y C C P Y  V D +         C    +  S
Sbjct: 432 CEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFS---------CTEHDECGS 482

Query: 64  GTETCRDSDELSEDGTMAACCCSVG-AAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
           G   C ++   +      +C C  G    G  C    E G   Y   C         + P
Sbjct: 483 GQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCR-YGGTCVAP---NKCVCP 538

Query: 123 PSYVVTLA--DIDECAAHEGLC-AHGTCTNTFGSFVCTCGAG------WSLAPXXXXXXX 173
             +  +    DIDEC+     C  H  C N  G + C C +G      +SL+        
Sbjct: 539 SGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDID 598

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                         C NL G + CLCP G
Sbjct: 599 ECALRTHTCWNDSACINLAGGFDCLCPSG 627



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 52/175 (29%), Positives = 73/175 (41%), Gaps = 36/175 (20%)

Query: 4   FNCTDVDECKSPQ-SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           F+CT+ DEC S Q +C +   C NT   ++C C P Y  V +GT C      R + +   
Sbjct: 472 FSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY--VGNGTIC------RAFCEEGC 523

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAY-RQLCPGGPGY 116
           R G  TC   ++         C C  G   G++C    D C E   E +    C   PG+
Sbjct: 524 RYG-GTCVAPNK---------CVCPSGFT-GSHCEKDIDECSEGIIECHNHSRCVNLPGW 572

Query: 117 ------QPVLEPPSYVV---TLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAG 161
                     +  +Y +   +  DIDECA     C +   C N  G F C C +G
Sbjct: 573 YHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 42/180 (23%), Positives = 63/180 (35%), Gaps = 12/180 (6%)

Query: 33  RCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWG 92
           +C    +++++G          C G V ++  TE C   +   +D  +    C       
Sbjct: 334 KCIYGGKVLAEGQRILTKSCRECRGGVLVKI-TEMCPPLNCSEKDHILPENQCCRVCRGH 392

Query: 93  NYCDPCPEPGSEAY------RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHG 145
           N+C   P+ G  +       +  C    GY  V    +Y     DIDECAA    C A+ 
Sbjct: 393 NFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYC---EDIDECAAKMHYCHANT 449

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEGYV 204
            C N  G + C C  G+                    C    +C N    + C C  GYV
Sbjct: 450 VCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV 509



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 1   MPGFNCTDVDECK-SPQSC-QYGQCINTQGSYTCRCP 35
           + G +C D+DEC     +C     CIN  G + C CP
Sbjct: 589 LSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCP 625


>BC096101-1|AAH96101.1|  810|Homo sapiens NEL-like 1 (chicken)
           protein.
          Length = 810

 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 53/209 (25%), Positives = 72/209 (34%), Gaps = 25/209 (11%)

Query: 6   CTDVDECKSPQSCQYGQ--CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           C D+DEC +     +    C+N  G Y C C P Y  V D +         C    +  S
Sbjct: 432 CEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFS---------CTEHDECGS 482

Query: 64  GTETCRDSDELSEDGTMAACCCSVG-AAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
           G   C ++   +      +C C  G    G  C    E G   Y   C         + P
Sbjct: 483 GQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCR-YGGTCVAP---NKCVCP 538

Query: 123 PSYVVTLA--DIDECAAHEGLC-AHGTCTNTFGSFVCTCGAG------WSLAPXXXXXXX 173
             +  +    DIDEC+     C  H  C N  G + C C +G      +SL+        
Sbjct: 539 SGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDID 598

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                         C NL G + CLCP G
Sbjct: 599 ECALRTHTCWNDSACINLAGGFDCLCPSG 627



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 52/175 (29%), Positives = 73/175 (41%), Gaps = 36/175 (20%)

Query: 4   FNCTDVDECKSPQ-SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           F+CT+ DEC S Q +C +   C NT   ++C C P Y  V +GT C      R + +   
Sbjct: 472 FSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY--VGNGTIC------RAFCEEGC 523

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAY-RQLCPGGPGY 116
           R G  TC   ++         C C  G   G++C    D C E   E +    C   PG+
Sbjct: 524 RYG-GTCVAPNK---------CVCPSGFT-GSHCEKDIDECSEGIIECHNHSRCVNLPGW 572

Query: 117 ------QPVLEPPSYVV---TLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAG 161
                     +  +Y +   +  DIDECA     C +   C N  G F C C +G
Sbjct: 573 YHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 42/180 (23%), Positives = 63/180 (35%), Gaps = 12/180 (6%)

Query: 33  RCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWG 92
           +C    +++++G          C G V ++  TE C   +   +D  +    C       
Sbjct: 334 KCIYGGKVLAEGQRILTKSCRECRGGVLVKI-TEMCPPLNCSEKDHILPENQCCRVCRGH 392

Query: 93  NYCDPCPEPGSEAY------RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHG 145
           N+C   P+ G  +       +  C    GY  V    +Y     DIDECAA    C A+ 
Sbjct: 393 NFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYC---EDIDECAAKMHYCHANT 449

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEGYV 204
            C N  G + C C  G+                    C    +C N    + C C  GYV
Sbjct: 450 VCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV 509



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 1   MPGFNCTDVDECK-SPQSC-QYGQCINTQGSYTCRCP 35
           + G +C D+DEC     +C     CIN  G + C CP
Sbjct: 589 LSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCP 625


>BC069674-1|AAH69674.1|  810|Homo sapiens nel-like 1, precursor
           protein.
          Length = 810

 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 53/209 (25%), Positives = 72/209 (34%), Gaps = 25/209 (11%)

Query: 6   CTDVDECKSPQSCQYGQ--CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           C D+DEC +     +    C+N  G Y C C P Y  V D +         C    +  S
Sbjct: 432 CEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFS---------CTEHDECGS 482

Query: 64  GTETCRDSDELSEDGTMAACCCSVG-AAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
           G   C ++   +      +C C  G    G  C    E G   Y   C         + P
Sbjct: 483 GQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCR-YGGTCVAP---NKCVCP 538

Query: 123 PSYVVTLA--DIDECAAHEGLC-AHGTCTNTFGSFVCTCGAG------WSLAPXXXXXXX 173
             +  +    DIDEC+     C  H  C N  G + C C +G      +SL+        
Sbjct: 539 SGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDID 598

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                         C NL G + CLCP G
Sbjct: 599 ECALRTHTCWNDSACINLAGGFDCLCPSG 627



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 52/175 (29%), Positives = 73/175 (41%), Gaps = 36/175 (20%)

Query: 4   FNCTDVDECKSPQ-SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           F+CT+ DEC S Q +C +   C NT   ++C C P Y  V +GT C      R + +   
Sbjct: 472 FSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY--VGNGTIC------RAFCEEGC 523

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAY-RQLCPGGPGY 116
           R G  TC   ++         C C  G   G++C    D C E   E +    C   PG+
Sbjct: 524 RYG-GTCVAPNK---------CVCPSGFT-GSHCEKDIDECSEGIIECHNHSRCVNLPGW 572

Query: 117 ------QPVLEPPSYVV---TLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAG 161
                     +  +Y +   +  DIDECA     C +   C N  G F C C +G
Sbjct: 573 YHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 42/180 (23%), Positives = 63/180 (35%), Gaps = 12/180 (6%)

Query: 33  RCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWG 92
           +C    +++++G          C G V ++  TE C   +   +D  +    C       
Sbjct: 334 KCIYGGKVLAEGQRILTKSCRECRGGVLVKI-TEMCPPLNCSEKDHILPENQCCRVCRGH 392

Query: 93  NYCDPCPEPGSEAY------RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLC-AHG 145
           N+C   P+ G  +       +  C    GY  V    +Y     DIDECAA    C A+ 
Sbjct: 393 NFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYC---EDIDECAAKMHYCHANT 449

Query: 146 TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VCRNLPGSYVCLCPEGYV 204
            C N  G + C C  G+                    C    +C N    + C C  GYV
Sbjct: 450 VCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV 509



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 1   MPGFNCTDVDECK-SPQSC-QYGQCINTQGSYTCRCP 35
           + G +C D+DEC     +C     CIN  G + C CP
Sbjct: 589 LSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCP 625


>X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for
           kidney epidermal growth factor (EGF) precursor. ).
          Length = 1207

 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 44/137 (32%), Positives = 54/137 (39%), Gaps = 17/137 (12%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DV+EC      C  G C NT GSY C CP  + L+ DG         RC+  V     
Sbjct: 354 CEDVNECAFWNHGCTLG-CKNTPGSYYCTCPVGFVLLPDG--------KRCHQLVSCPRN 404

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLC-PGGPGYQPVL 120
              C     L+ +G +  C C  G+     G  C  C  P +    QLC P  P      
Sbjct: 405 VSECSHDCVLTSEGPL--CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECD 462

Query: 121 EPPSYVVTLADIDECAA 137
             P Y + L D   CAA
Sbjct: 463 CFPGYDLQL-DEKSCAA 478



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 48/186 (25%), Positives = 65/186 (34%), Gaps = 10/186 (5%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACY--DSRKARCYGKVDLRSGTETCR--DSDELSEDG 78
           C    G+  C C   +   SDG  C   D  +    G+VDL++            +SED 
Sbjct: 756 CKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDN 815

Query: 79  TMAACCCSVGAAWGNYCDPCPEPGSEAY-RQLCPGGPGYQPVLEPPSYVVTL-ADIDECA 136
              +    V     +  D C   G   Y R +  G       L+  +    L +DIDEC 
Sbjct: 816 ITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECE 875

Query: 137 AHEGLC--AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV-CRNLPG 193
               +C  A   C NT G +VC C  G+                    CG    C N  G
Sbjct: 876 MGVPVCPPASSKCINTEGGYVCRCSEGYQ-GDGIHCLDIDECQLGVHSCGENASCTNTEG 934

Query: 194 SYVCLC 199
            Y C+C
Sbjct: 935 GYTCMC 940



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCRNLPG 193
           C   +G C+   C     S +C C  G++L+                  C  G C+N PG
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPG 376

Query: 194 SYVCLCPEGYVAMPNGSQ 211
           SY C CP G+V +P+G +
Sbjct: 377 SYYCTCPVGFVLLPDGKR 394



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 43/164 (26%), Positives = 61/164 (37%), Gaps = 31/164 (18%)

Query: 6    CTDVDECK-SPQSCQ--YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            C+D+DEC+     C     +CINT+G Y CRC   Y+   DG  C D  + +        
Sbjct: 868  CSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQ--GDGIHCLDIDECQL------- 918

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
             G  +C         G  A+C  + G           EPG      +CP       + E 
Sbjct: 919  -GVHSC---------GENASCTNTEGGYTCMCAGRLSEPG-----LICPDSTPPPHLRED 963

Query: 123  PSYVVTLADIDEC-AAHEGLCAH-GTC--TNTFGSFVCTCGAGW 162
              +        EC  +H+G C H G C        + C C  G+
Sbjct: 964  DHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGY 1007



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 4/78 (5%)

Query: 3   GFNCTDVDECK-SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G +C D+DEC+    SC +   C NT+G YTC C     L   G  C DS       + D
Sbjct: 907 GIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAG--RLSEPGLICPDSTPPPHLREDD 964

Query: 61  LRSGTETCRDSDELSEDG 78
                        LS DG
Sbjct: 965 HHYSVRNSDSECPLSHDG 982



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 3/80 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP-DVCGPGVCR 189
           D++ECA     C  G C NT GS+ CTC  G+ L P            R    C      
Sbjct: 356 DVNECAFWNHGCTLG-CKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVL 414

Query: 190 NLPGSYVCLCPEGYVAMPNG 209
              G  +C CPEG V   +G
Sbjct: 415 TSEGP-LCFCPEGSVLERDG 433



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 23/79 (29%), Positives = 31/79 (39%), Gaps = 4/79 (5%)

Query: 127 VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
           + ++D D+CA   G   +  C +      C C  G++                P VC P 
Sbjct: 827 IMVSDQDDCAP-VGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVP-VCPPA 884

Query: 187 V--CRNLPGSYVCLCPEGY 203
              C N  G YVC C EGY
Sbjct: 885 SSKCINTEGGYVCRCSEGY 903


>BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor
           (beta-urogastrone) protein.
          Length = 1207

 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 44/137 (32%), Positives = 54/137 (39%), Gaps = 17/137 (12%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DV+EC      C  G C NT GSY C CP  + L+ DG         RC+  V     
Sbjct: 354 CEDVNECAFWNHGCTLG-CKNTPGSYYCTCPVGFVLLPDG--------KRCHQLVSCPRN 404

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLC-PGGPGYQPVL 120
              C     L+ +G +  C C  G+     G  C  C  P +    QLC P  P      
Sbjct: 405 VSECSHDCVLTSEGPL--CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECD 462

Query: 121 EPPSYVVTLADIDECAA 137
             P Y + L D   CAA
Sbjct: 463 CFPGYDLQL-DEKSCAA 478



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 48/186 (25%), Positives = 65/186 (34%), Gaps = 10/186 (5%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACY--DSRKARCYGKVDLRSGTETCR--DSDELSEDG 78
           C    G+  C C   +   SDG  C   D  +    G+VDL++            +SED 
Sbjct: 756 CKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDN 815

Query: 79  TMAACCCSVGAAWGNYCDPCPEPGSEAY-RQLCPGGPGYQPVLEPPSYVVTL-ADIDECA 136
              +    V     +  D C   G   Y R +  G       L+  +    L +DIDEC 
Sbjct: 816 ITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECE 875

Query: 137 AHEGLC--AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV-CRNLPG 193
               +C  A   C NT G +VC C  G+                    CG    C N  G
Sbjct: 876 MGVPVCPPASSKCINTEGGYVCRCSEGYQ-GDGIHCLDIDECQLGVHSCGENASCTNTEG 934

Query: 194 SYVCLC 199
            Y C+C
Sbjct: 935 GYTCMC 940



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCRNLPG 193
           C   +G C+   C     S +C C  G++L+                  C  G C+N PG
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPG 376

Query: 194 SYVCLCPEGYVAMPNGSQ 211
           SY C CP G+V +P+G +
Sbjct: 377 SYYCTCPVGFVLLPDGKR 394



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 43/164 (26%), Positives = 61/164 (37%), Gaps = 31/164 (18%)

Query: 6    CTDVDECK-SPQSCQ--YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            C+D+DEC+     C     +CINT+G Y CRC   Y+   DG  C D  + +        
Sbjct: 868  CSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQ--GDGIHCLDIDECQL------- 918

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
             G  +C         G  A+C  + G           EPG      +CP       + E 
Sbjct: 919  -GVHSC---------GENASCTNTEGGYTCMCAGRLSEPG-----LICPDSTPPPHLRED 963

Query: 123  PSYVVTLADIDEC-AAHEGLCAH-GTC--TNTFGSFVCTCGAGW 162
              +        EC  +H+G C H G C        + C C  G+
Sbjct: 964  DHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGY 1007



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 4/78 (5%)

Query: 3   GFNCTDVDECK-SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G +C D+DEC+    SC +   C NT+G YTC C     L   G  C DS       + D
Sbjct: 907 GIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAG--RLSEPGLICPDSTPPPHLREDD 964

Query: 61  LRSGTETCRDSDELSEDG 78
                        LS DG
Sbjct: 965 HHYSVRNSDSECPLSHDG 982



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 3/80 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP-DVCGPGVCR 189
           D++ECA     C  G C NT GS+ CTC  G+ L P            R    C      
Sbjct: 356 DVNECAFWNHGCTLG-CKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVL 414

Query: 190 NLPGSYVCLCPEGYVAMPNG 209
              G  +C CPEG V   +G
Sbjct: 415 TSEGP-LCFCPEGSVLERDG 433



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 23/79 (29%), Positives = 31/79 (39%), Gaps = 4/79 (5%)

Query: 127 VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
           + ++D D+CA   G   +  C +      C C  G++                P VC P 
Sbjct: 827 IMVSDQDDCAP-VGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVP-VCPPA 884

Query: 187 V--CRNLPGSYVCLCPEGY 203
              C N  G YVC C EGY
Sbjct: 885 SSKCINTEGGYVCRCSEGY 903


>BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor
           (beta-urogastrone) protein.
          Length = 1207

 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 44/137 (32%), Positives = 54/137 (39%), Gaps = 17/137 (12%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DV+EC      C  G C NT GSY C CP  + L+ DG         RC+  V     
Sbjct: 354 CEDVNECAFWNHGCTLG-CKNTPGSYYCTCPVGFVLLPDG--------KRCHQLVSCPRN 404

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLC-PGGPGYQPVL 120
              C     L+ +G +  C C  G+     G  C  C  P +    QLC P  P      
Sbjct: 405 VSECSHDCVLTSEGPL--CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECD 462

Query: 121 EPPSYVVTLADIDECAA 137
             P Y + L D   CAA
Sbjct: 463 CFPGYDLQL-DEKSCAA 478



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 48/186 (25%), Positives = 65/186 (34%), Gaps = 10/186 (5%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACY--DSRKARCYGKVDLRSGTETCR--DSDELSEDG 78
           C    G+  C C   +   SDG  C   D  +    G+VDL++            +SED 
Sbjct: 756 CKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDN 815

Query: 79  TMAACCCSVGAAWGNYCDPCPEPGSEAY-RQLCPGGPGYQPVLEPPSYVVTL-ADIDECA 136
              +    V     +  D C   G   Y R +  G       L+  +    L +DIDEC 
Sbjct: 816 ITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECE 875

Query: 137 AHEGLC--AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV-CRNLPG 193
               +C  A   C NT G +VC C  G+                    CG    C N  G
Sbjct: 876 MGVPVCPPASSKCINTEGGYVCRCSEGYQ-GDGIHCLDIDECQLGVHSCGENASCTNTEG 934

Query: 194 SYVCLC 199
            Y C+C
Sbjct: 935 GYTCMC 940



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCRNLPG 193
           C   +G C+   C     S +C C  G++L+                  C  G C+N PG
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPG 376

Query: 194 SYVCLCPEGYVAMPNGSQ 211
           SY C CP G+V +P+G +
Sbjct: 377 SYYCTCPVGFVLLPDGKR 394



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 43/164 (26%), Positives = 61/164 (37%), Gaps = 31/164 (18%)

Query: 6    CTDVDECK-SPQSCQ--YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            C+D+DEC+     C     +CINT+G Y CRC   Y+   DG  C D  + +        
Sbjct: 868  CSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQ--GDGIHCLDIDECQL------- 918

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
             G  +C         G  A+C  + G           EPG      +CP       + E 
Sbjct: 919  -GVHSC---------GENASCTNTEGGYTCMCAGRLSEPG-----LICPDSTPPPHLRED 963

Query: 123  PSYVVTLADIDEC-AAHEGLCAH-GTC--TNTFGSFVCTCGAGW 162
              +        EC  +H+G C H G C        + C C  G+
Sbjct: 964  DHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGY 1007



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 4/78 (5%)

Query: 3   GFNCTDVDECK-SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G +C D+DEC+    SC +   C NT+G YTC C     L   G  C DS       + D
Sbjct: 907 GIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAG--RLSEPGLICPDSTPPPHLREDD 964

Query: 61  LRSGTETCRDSDELSEDG 78
                        LS DG
Sbjct: 965 HHYSVRNSDSECPLSHDG 982



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 3/80 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP-DVCGPGVCR 189
           D++ECA     C  G C NT GS+ CTC  G+ L P            R    C      
Sbjct: 356 DVNECAFWNHGCTLG-CKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVL 414

Query: 190 NLPGSYVCLCPEGYVAMPNG 209
              G  +C CPEG V   +G
Sbjct: 415 TSEGP-LCFCPEGSVLERDG 433



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 23/79 (29%), Positives = 31/79 (39%), Gaps = 4/79 (5%)

Query: 127 VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
           + ++D D+CA   G   +  C +      C C  G++                P VC P 
Sbjct: 827 IMVSDQDDCAP-VGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVP-VCPPA 884

Query: 187 V--CRNLPGSYVCLCPEGY 203
              C N  G YVC C EGY
Sbjct: 885 SSKCINTEGGYVCRCSEGY 903


>AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal growth
           factor (beta-urogastrone) protein.
          Length = 1152

 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 44/137 (32%), Positives = 54/137 (39%), Gaps = 17/137 (12%)

Query: 6   CTDVDECKS-PQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSG 64
           C DV+EC      C  G C NT GSY C CP  + L+ DG         RC+  V     
Sbjct: 354 CEDVNECAFWNHGCTLG-CKNTPGSYYCTCPVGFVLLPDG--------KRCHQLVSCPRN 404

Query: 65  TETCRDSDELSEDGTMAACCCSVGAAW---GNYCDPCPEPGSEAYRQLC-PGGPGYQPVL 120
              C     L+ +G +  C C  G+     G  C  C  P +    QLC P  P      
Sbjct: 405 VSECSHDCVLTSEGPL--CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECD 462

Query: 121 EPPSYVVTLADIDECAA 137
             P Y + L D   CAA
Sbjct: 463 CFPGYDLQL-DEKSCAA 478



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 48/186 (25%), Positives = 65/186 (34%), Gaps = 10/186 (5%)

Query: 23  CINTQGSYTCRCPPNYELVSDGTACY--DSRKARCYGKVDLRSGTETCR--DSDELSEDG 78
           C    G+  C C   +   SDG  C   D  +    G+VDL++            +SED 
Sbjct: 756 CKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDN 815

Query: 79  TMAACCCSVGAAWGNYCDPCPEPGSEAY-RQLCPGGPGYQPVLEPPSYVVTL-ADIDECA 136
              +    V     +  D C   G   Y R +  G       L+  +    L +DIDEC 
Sbjct: 816 ITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECE 875

Query: 137 AHEGLC--AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV-CRNLPG 193
               +C  A   C NT G +VC C  G+                    CG    C N  G
Sbjct: 876 MGVPVCPPASSKCINTEGGYVCRCSEGYQ-GDGIHCLDIDECQLGVHSCGENASCTNTEG 934

Query: 194 SYVCLC 199
            Y C+C
Sbjct: 935 GYTCMC 940



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 135 CAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX-XXRPDVCGPGVCRNLPG 193
           C   +G C+   C     S +C C  G++L+                  C  G C+N PG
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPG 376

Query: 194 SYVCLCPEGYVAMPNGSQ 211
           SY C CP G+V +P+G +
Sbjct: 377 SYYCTCPVGFVLLPDGKR 394



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 43/164 (26%), Positives = 61/164 (37%), Gaps = 31/164 (18%)

Query: 6    CTDVDECK-SPQSCQ--YGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLR 62
            C+D+DEC+     C     +CINT+G Y CRC   Y+   DG  C D  + +        
Sbjct: 868  CSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQ--GDGIHCLDIDECQL------- 918

Query: 63   SGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
             G  +C         G  A+C  + G           EPG      +CP       + E 
Sbjct: 919  -GVHSC---------GENASCTNTEGGYTCMCAGRLSEPG-----LICPDSTPPPHLRED 963

Query: 123  PSYVVTLADIDEC-AAHEGLCAH-GTC--TNTFGSFVCTCGAGW 162
              +        EC  +H+G C H G C        + C C  G+
Sbjct: 964  DHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGY 1007



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 4/78 (5%)

Query: 3   GFNCTDVDECK-SPQSC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G +C D+DEC+    SC +   C NT+G YTC C     L   G  C DS       + D
Sbjct: 907 GIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAG--RLSEPGLICPDSTPPPHLREDD 964

Query: 61  LRSGTETCRDSDELSEDG 78
                        LS DG
Sbjct: 965 HHYSVRNSDSECPLSHDG 982



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 3/80 (3%)

Query: 131 DIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP-DVCGPGVCR 189
           D++ECA     C  G C NT GS+ CTC  G+ L P            R    C      
Sbjct: 356 DVNECAFWNHGCTLG-CKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVL 414

Query: 190 NLPGSYVCLCPEGYVAMPNG 209
              G  +C CPEG V   +G
Sbjct: 415 TSEGP-LCFCPEGSVLERDG 433



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 23/79 (29%), Positives = 31/79 (39%), Gaps = 4/79 (5%)

Query: 127 VTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG 186
           + ++D D+CA   G   +  C +      C C  G++                P VC P 
Sbjct: 827 IMVSDQDDCAP-VGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVP-VCPPA 884

Query: 187 V--CRNLPGSYVCLCPEGY 203
              C N  G YVC C EGY
Sbjct: 885 SSKCINTEGGYVCRCSEGY 903


>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
           protein.
          Length = 1214

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 56/203 (27%), Positives = 76/203 (37%), Gaps = 26/203 (12%)

Query: 7   TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSG 64
           T++D+C SP +C +G  C +    + C CPP +     G  C  D+ +      V+ +S 
Sbjct: 360 TNIDDC-SPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSC 414

Query: 65  TETCRDSDELSEDGTMAACC-CSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLE 121
                        G M   C  ++    G  C  D         YR +CP  PGY     
Sbjct: 415 KNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICP--PGY----- 466

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
             +      DIDECA++  L   G C N    F C C  G+S                P+
Sbjct: 467 --AGDHCERDIDECASNPCLNG-GHCQNEINRFQCLCPTGFS----GNLCQLDIDYCEPN 519

Query: 182 VCGPGV-CRNLPGSYVCLCPEGY 203
            C  G  C N    Y C CPE Y
Sbjct: 520 PCQNGAQCYNRASDYFCKCPEDY 542



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 54/205 (26%), Positives = 73/205 (35%), Gaps = 30/205 (14%)

Query: 8   DVDECKSPQSC-QYGQCINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C + Q C   G C NT    Y C CP  Y     G  C  +  A C         +
Sbjct: 283 DLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYS----GPNCEIAEHA-CL--------S 329

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGYQPVL 120
           + C +     E      C CS G  W G  C    D C  P + ++   C         +
Sbjct: 330 DPCHNRGSCKETSLGFECECSPG--WTGPTCSTNIDDC-SPNNCSHGGTCQDLVNGFKCV 386

Query: 121 EPPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            PP +      +D  EC A   + A  +C N   S+ C C  GW                
Sbjct: 387 CPPQWTGKTCQLDANECEAKPCVNAK-SCKNLIASYYCDCLPGWMGQNCDININDCLGQC 445

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
           + D      CR+L   Y C+CP GY
Sbjct: 446 QNDAS----CRDLVNGYRCICPPGY 466



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 53/201 (26%), Positives = 77/201 (38%), Gaps = 33/201 (16%)

Query: 8   DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           D+D C+ P  CQ G QC N    Y C+CP +YE    G  C    K  C         T 
Sbjct: 512 DIDYCE-PNPCQNGAQCYNRASDYFCKCPEDYE----GKNC-SHLKDHC--------RTT 557

Query: 67  TCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQL-CPGGPGYQPVLEPP 123
            C   D  +    MA+     G  +   N C P  +  S++  +  C    G+       
Sbjct: 558 PCEVIDSCTV--AMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF------- 608

Query: 124 SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +      +I++C ++   C + GTC +   S+ C C  GW  A              P  
Sbjct: 609 TGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGWEGA--YCETNINDCSQNPCH 664

Query: 183 CGPGVCRNLPGSYVCLCPEGY 203
            G G CR+L   + C C  G+
Sbjct: 665 NG-GTCRDLVNDFYCDCKNGW 684



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 36/153 (23%), Positives = 60/153 (39%), Gaps = 17/153 (11%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           PGF   +C  +++EC+S   C +G  C++    Y C CPP +     G  C +     C 
Sbjct: 797 PGFAGPDCRININECQS-SPCAFGATCVDEINGYRCVCPPGH----SGAKCQEVSGRPC- 850

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
               +  G+    D  +  +D     C     A    +C P P    + + + CP G   
Sbjct: 851 ----ITMGS-VIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSE-CPSGQSC 904

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTN 149
            P+L+   +V     + EC +         CT+
Sbjct: 905 IPILDDQCFVHPCTGVGECRSSSLQPVKTKCTS 937



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 58/218 (26%), Positives = 80/218 (36%), Gaps = 44/218 (20%)

Query: 12  CKSPQSC--QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           CK P  C  QYG     QG Y  +C P+   V     C +  +  C    +   G + C 
Sbjct: 232 CKLPGDCRCQYGW----QGLYCDKCIPHPGCVHG--ICNEPWQCLC----ETNWGGQLC- 280

Query: 70  DSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGP------ 114
           D D L+  GT   C     C + G     Y   CPE    P  E     C   P      
Sbjct: 281 DKD-LNYCGTHQPCLNGGTCSNTGP--DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGS 337

Query: 115 ------GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAP 166
                 G++    P     T + +ID+C+ +   C+HG TC +    F C C   W+   
Sbjct: 338 CKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCPPQWT--G 393

Query: 167 XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +P V     C+NL  SY C C  G++
Sbjct: 394 KTCQLDANECEAKPCVNAKS-CKNLIASYYCDCLPGWM 430



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 52/206 (25%), Positives = 75/206 (36%), Gaps = 32/206 (15%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           ++++C+S      G CI+   SY C C   +E     T   D  +  C+       GT  
Sbjct: 616 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHN-----GGT-- 668

Query: 68  CRD--SDELSE--DGTMAACCCSVGA----AWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           CRD  +D   +  +G     C S  +    A  N    C + G +A++ +CPGG      
Sbjct: 669 CRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG-DAFKCMCPGGW----- 722

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                    +A    C  +   C +G TC     SF C C  GW   P            
Sbjct: 723 ---EGTTCNIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGWE-GPICAQNTNDCS-- 774

Query: 179 RPDVC-GPGVCRNLPGSYVCLCPEGY 203
            P  C   G C +    Y C C  G+
Sbjct: 775 -PHPCYNSGTCVDGDNWYRCECAPGF 799



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 1/37 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY 38
           G +C  D+DEC S      G C N    + C CP  +
Sbjct: 468 GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF 504


>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
          Length = 1218

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 56/203 (27%), Positives = 76/203 (37%), Gaps = 26/203 (12%)

Query: 7   TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSG 64
           T++D+C SP +C +G  C +    + C CPP +     G  C  D+ +      V+ +S 
Sbjct: 373 TNIDDC-SPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSC 427

Query: 65  TETCRDSDELSEDGTMAACC-CSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLE 121
                        G M   C  ++    G  C  D         YR +CP  PGY     
Sbjct: 428 KNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICP--PGY----- 479

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
             +      DIDECA++  L   G C N    F C C  G+S                P+
Sbjct: 480 --AGDHCERDIDECASNPCLNG-GHCQNEINRFQCLCPTGFS----GNLCQLDIDYCEPN 532

Query: 182 VCGPGV-CRNLPGSYVCLCPEGY 203
            C  G  C N    Y C CPE Y
Sbjct: 533 PCQNGAQCYNRASDYFCKCPEDY 555



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 54/205 (26%), Positives = 73/205 (35%), Gaps = 30/205 (14%)

Query: 8   DVDECKSPQSC-QYGQCINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C + Q C   G C NT    Y C CP  Y     G  C  +  A C         +
Sbjct: 296 DLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYS----GPNCEIAEHA-CL--------S 342

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGYQPVL 120
           + C +     E      C CS G  W G  C    D C  P + ++   C         +
Sbjct: 343 DPCHNRGSCKETSLGFECECSPG--WTGPTCSTNIDDC-SPNNCSHGGTCQDLVNGFKCV 399

Query: 121 EPPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            PP +      +D  EC A   + A  +C N   S+ C C  GW                
Sbjct: 400 CPPQWTGKTCQLDANECEAKPCVNAK-SCKNLIASYYCDCLPGWMGQNCDININDCLGQC 458

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
           + D      CR+L   Y C+CP GY
Sbjct: 459 QNDAS----CRDLVNGYRCICPPGY 479



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 53/201 (26%), Positives = 77/201 (38%), Gaps = 33/201 (16%)

Query: 8   DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           D+D C+ P  CQ G QC N    Y C+CP +YE    G  C    K  C         T 
Sbjct: 525 DIDYCE-PNPCQNGAQCYNRASDYFCKCPEDYE----GKNC-SHLKDHC--------RTT 570

Query: 67  TCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQL-CPGGPGYQPVLEPP 123
            C   D  +    MA+     G  +   N C P  +  S++  +  C    G+       
Sbjct: 571 PCEVIDSCTV--AMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF------- 621

Query: 124 SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +      +I++C ++   C + GTC +   S+ C C  GW  A              P  
Sbjct: 622 TGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGWEGA--YCETNINDCSQNPCH 677

Query: 183 CGPGVCRNLPGSYVCLCPEGY 203
            G G CR+L   + C C  G+
Sbjct: 678 NG-GTCRDLVNDFYCDCKNGW 697



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 36/153 (23%), Positives = 60/153 (39%), Gaps = 17/153 (11%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           PGF   +C  +++EC+S   C +G  C++    Y C CPP +     G  C +     C 
Sbjct: 810 PGFAGPDCRININECQS-SPCAFGATCVDEINGYRCVCPPGH----SGAKCQEVSGRPC- 863

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
               +  G+    D  +  +D     C     A    +C P P    + + + CP G   
Sbjct: 864 ----ITMGS-VIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSE-CPSGQSC 917

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTN 149
            P+L+   +V     + EC +         CT+
Sbjct: 918 IPILDDQCFVHPCTGVGECRSSSLQPVKTKCTS 950



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 58/218 (26%), Positives = 80/218 (36%), Gaps = 44/218 (20%)

Query: 12  CKSPQSC--QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           CK P  C  QYG     QG Y  +C P+   V     C +  +  C    +   G + C 
Sbjct: 245 CKLPGDCRCQYGW----QGLYCDKCIPHPGCVHG--ICNEPWQCLC----ETNWGGQLC- 293

Query: 70  DSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGP------ 114
           D D L+  GT   C     C + G     Y   CPE    P  E     C   P      
Sbjct: 294 DKD-LNYCGTHQPCLNGGTCSNTGP--DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGS 350

Query: 115 ------GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAP 166
                 G++    P     T + +ID+C+ +   C+HG TC +    F C C   W+   
Sbjct: 351 CKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCPPQWT--G 406

Query: 167 XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +P V     C+NL  SY C C  G++
Sbjct: 407 KTCQLDANECEAKPCVNAKS-CKNLIASYYCDCLPGWM 443



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 52/206 (25%), Positives = 75/206 (36%), Gaps = 32/206 (15%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           ++++C+S      G CI+   SY C C   +E     T   D  +  C+       GT  
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHN-----GGT-- 681

Query: 68  CRD--SDELSE--DGTMAACCCSVGA----AWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           CRD  +D   +  +G     C S  +    A  N    C + G +A++ +CPGG      
Sbjct: 682 CRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG-DAFKCMCPGGW----- 735

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                    +A    C  +   C +G TC     SF C C  GW   P            
Sbjct: 736 ---EGTTCNIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGWE-GPICAQNTNDCS-- 787

Query: 179 RPDVC-GPGVCRNLPGSYVCLCPEGY 203
            P  C   G C +    Y C C  G+
Sbjct: 788 -PHPCYNSGTCVDGDNWYRCECAPGF 812



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 1/37 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY 38
           G +C  D+DEC S      G C N    + C CP  +
Sbjct: 481 GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF 517


>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged
           1 protein.
          Length = 1218

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 56/203 (27%), Positives = 76/203 (37%), Gaps = 26/203 (12%)

Query: 7   TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSG 64
           T++D+C SP +C +G  C +    + C CPP +     G  C  D+ +      V+ +S 
Sbjct: 373 TNIDDC-SPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSC 427

Query: 65  TETCRDSDELSEDGTMAACC-CSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLE 121
                        G M   C  ++    G  C  D         YR +CP  PGY     
Sbjct: 428 KNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICP--PGY----- 479

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
             +      DIDECA++  L   G C N    F C C  G+S                P+
Sbjct: 480 --AGDHCERDIDECASNPCLNG-GHCQNEINRFQCLCPTGFS----GNLCQLDIDYCEPN 532

Query: 182 VCGPGV-CRNLPGSYVCLCPEGY 203
            C  G  C N    Y C CPE Y
Sbjct: 533 PCQNGAQCYNRASDYFCKCPEDY 555



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 54/205 (26%), Positives = 73/205 (35%), Gaps = 30/205 (14%)

Query: 8   DVDECKSPQSC-QYGQCINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C + Q C   G C NT    Y C CP  Y     G  C  +  A C         +
Sbjct: 296 DLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYS----GPNCEIAEHA-CL--------S 342

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGYQPVL 120
           + C +     E      C CS G  W G  C    D C  P + ++   C         +
Sbjct: 343 DPCHNRGSCKETSLGFECECSPG--WTGPTCSTNIDDC-SPNNCSHGGTCQDLVNGFKCV 399

Query: 121 EPPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            PP +      +D  EC A   + A  +C N   S+ C C  GW                
Sbjct: 400 CPPQWTGKTCQLDANECEAKPCVNAK-SCKNLIASYYCDCLPGWMGQNCDININDCLGQC 458

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
           + D      CR+L   Y C+CP GY
Sbjct: 459 QNDAS----CRDLVNGYRCICPPGY 479



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 53/201 (26%), Positives = 77/201 (38%), Gaps = 33/201 (16%)

Query: 8   DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           D+D C+ P  CQ G QC N    Y C+CP +YE    G  C    K  C         T 
Sbjct: 525 DIDYCE-PNPCQNGAQCYNRASDYFCKCPEDYE----GKNC-SHLKDHC--------RTT 570

Query: 67  TCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQL-CPGGPGYQPVLEPP 123
            C   D  +    MA+     G  +   N C P  +  S++  +  C    G+       
Sbjct: 571 PCEVIDSCTV--AMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF------- 621

Query: 124 SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +      +I++C ++   C + GTC +   S+ C C  GW  A              P  
Sbjct: 622 TGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGWEGA--YCETNINDCSQNPCH 677

Query: 183 CGPGVCRNLPGSYVCLCPEGY 203
            G G CR+L   + C C  G+
Sbjct: 678 NG-GTCRDLVNDFYCDCKNGW 697



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 36/153 (23%), Positives = 60/153 (39%), Gaps = 17/153 (11%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           PGF   +C  +++EC+S   C +G  C++    Y C CPP +     G  C +     C 
Sbjct: 810 PGFAGPDCRININECQS-SPCAFGATCVDEINGYRCVCPPGH----SGAKCQEVSGRPC- 863

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
               +  G+    D  +  +D     C     A    +C P P    + + + CP G   
Sbjct: 864 ----ITMGS-VIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSE-CPSGQSC 917

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTN 149
            P+L+   +V     + EC +         CT+
Sbjct: 918 IPILDDQCFVHPCTGVGECRSSSLQPVKTKCTS 950



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 58/218 (26%), Positives = 80/218 (36%), Gaps = 44/218 (20%)

Query: 12  CKSPQSC--QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           CK P  C  QYG     QG Y  +C P+   V     C +  +  C    +   G + C 
Sbjct: 245 CKLPGDCRCQYGW----QGLYCDKCIPHPGCVHG--ICNEPWQCLC----ETNWGGQLC- 293

Query: 70  DSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGP------ 114
           D D L+  GT   C     C + G     Y   CPE    P  E     C   P      
Sbjct: 294 DKD-LNYCGTHQPCLNGGTCSNTGP--DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGS 350

Query: 115 ------GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAP 166
                 G++    P     T + +ID+C+ +   C+HG TC +    F C C   W+   
Sbjct: 351 CKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCPPQWT--G 406

Query: 167 XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +P V     C+NL  SY C C  G++
Sbjct: 407 KTCQLDANECEAKPCVNAKS-CKNLIASYYCDCLPGWM 443



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 52/206 (25%), Positives = 75/206 (36%), Gaps = 32/206 (15%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           ++++C+S      G CI+   SY C C   +E     T   D  +  C+       GT  
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHN-----GGT-- 681

Query: 68  CRD--SDELSE--DGTMAACCCSVGA----AWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           CRD  +D   +  +G     C S  +    A  N    C + G +A++ +CPGG      
Sbjct: 682 CRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG-DAFKCMCPGGW----- 735

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                    +A    C  +   C +G TC     SF C C  GW   P            
Sbjct: 736 ---EGTTCNIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGWE-GPICAQNTNDCS-- 787

Query: 179 RPDVC-GPGVCRNLPGSYVCLCPEGY 203
            P  C   G C +    Y C C  G+
Sbjct: 788 -PHPCYNSGTCVDGDNWYRCECAPGF 812



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 1/37 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY 38
           G +C  D+DEC S      G C N    + C CP  +
Sbjct: 481 GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF 517


>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille
           syndrome) protein.
          Length = 1218

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 56/203 (27%), Positives = 76/203 (37%), Gaps = 26/203 (12%)

Query: 7   TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSG 64
           T++D+C SP +C +G  C +    + C CPP +     G  C  D+ +      V+ +S 
Sbjct: 373 TNIDDC-SPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSC 427

Query: 65  TETCRDSDELSEDGTMAACC-CSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLE 121
                        G M   C  ++    G  C  D         YR +CP  PGY     
Sbjct: 428 KNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICP--PGY----- 479

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
             +      DIDECA++  L   G C N    F C C  G+S                P+
Sbjct: 480 --AGDHCERDIDECASNPCLNG-GHCQNEINRFQCLCPTGFS----GNLCQLDIDYCEPN 532

Query: 182 VCGPGV-CRNLPGSYVCLCPEGY 203
            C  G  C N    Y C CPE Y
Sbjct: 533 PCQNGAQCYNRASDYFCKCPEDY 555



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 54/205 (26%), Positives = 73/205 (35%), Gaps = 30/205 (14%)

Query: 8   DVDECKSPQSC-QYGQCINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C + Q C   G C NT    Y C CP  Y     G  C  +  A C         +
Sbjct: 296 DLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYS----GPNCEIAEHA-CL--------S 342

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGYQPVL 120
           + C +     E      C CS G  W G  C    D C  P + ++   C         +
Sbjct: 343 DPCHNRGSCKETSLGFECECSPG--WTGPTCSTNIDDC-SPNNCSHGGTCQDLVNGFKCV 399

Query: 121 EPPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            PP +      +D  EC A   + A  +C N   S+ C C  GW                
Sbjct: 400 CPPQWTGKTCQLDANECEAKPCVNAK-SCKNLIASYYCDCLPGWMGQNCDININDCLGQC 458

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
           + D      CR+L   Y C+CP GY
Sbjct: 459 QNDAS----CRDLVNGYRCICPPGY 479



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 53/201 (26%), Positives = 77/201 (38%), Gaps = 33/201 (16%)

Query: 8   DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           D+D C+ P  CQ G QC N    Y C+CP +YE    G  C    K  C         T 
Sbjct: 525 DIDYCE-PNPCQNGAQCYNRASDYFCKCPEDYE----GKNC-SHLKDHC--------RTT 570

Query: 67  TCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQL-CPGGPGYQPVLEPP 123
            C   D  +    MA+     G  +   N C P  +  S++  +  C    G+       
Sbjct: 571 PCEVIDSCTV--AMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF------- 621

Query: 124 SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +      +I++C ++   C + GTC +   S+ C C  GW  A              P  
Sbjct: 622 TGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGWEGA--YCETNINDCSQNPCH 677

Query: 183 CGPGVCRNLPGSYVCLCPEGY 203
            G G CR+L   + C C  G+
Sbjct: 678 NG-GTCRDLVNDFYCDCKNGW 697



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 36/153 (23%), Positives = 60/153 (39%), Gaps = 17/153 (11%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           PGF   +C  +++EC+S   C +G  C++    Y C CPP +     G  C +     C 
Sbjct: 810 PGFAGPDCRININECQS-SPCAFGATCVDEINGYRCVCPPGH----SGAKCQEVSGRPC- 863

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
               +  G+    D  +  +D     C     A    +C P P    + + + CP G   
Sbjct: 864 ----ITMGS-VIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSE-CPSGQSC 917

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTN 149
            P+L+   +V     + EC +         CT+
Sbjct: 918 IPILDDQCFVHPCTGVGECRSSSLQPVKTKCTS 950



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 58/218 (26%), Positives = 80/218 (36%), Gaps = 44/218 (20%)

Query: 12  CKSPQSC--QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           CK P  C  QYG     QG Y  +C P+   V     C +  +  C    +   G + C 
Sbjct: 245 CKLPGDCRCQYGW----QGLYCDKCIPHPGCVHG--ICNEPWQCLC----ETNWGGQLC- 293

Query: 70  DSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGP------ 114
           D D L+  GT   C     C + G     Y   CPE    P  E     C   P      
Sbjct: 294 DKD-LNYCGTHQPCLNGGTCSNTGP--DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGS 350

Query: 115 ------GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAP 166
                 G++    P     T + +ID+C+ +   C+HG TC +    F C C   W+   
Sbjct: 351 CKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCPPQWT--G 406

Query: 167 XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +P V     C+NL  SY C C  G++
Sbjct: 407 KTCQLDANECEAKPCVNAKS-CKNLIASYYCDCLPGWM 443



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 52/206 (25%), Positives = 75/206 (36%), Gaps = 32/206 (15%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           ++++C+S      G CI+   SY C C   +E     T   D  +  C+       GT  
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHN-----GGT-- 681

Query: 68  CRD--SDELSE--DGTMAACCCSVGA----AWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           CRD  +D   +  +G     C S  +    A  N    C + G +A++ +CPGG      
Sbjct: 682 CRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG-DAFKCMCPGGW----- 735

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                    +A    C  +   C +G TC     SF C C  GW   P            
Sbjct: 736 ---EGTTCNIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGWE-GPICAQNTNDCS-- 787

Query: 179 RPDVC-GPGVCRNLPGSYVCLCPEGY 203
            P  C   G C +    Y C C  G+
Sbjct: 788 -PHPCYNSGTCVDGDNWYRCECAPGF 812



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 1/37 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY 38
           G +C  D+DEC S      G C N    + C CP  +
Sbjct: 481 GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF 517


>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille
           syndrome) protein.
          Length = 1218

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 56/203 (27%), Positives = 76/203 (37%), Gaps = 26/203 (12%)

Query: 7   TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSG 64
           T++D+C SP +C +G  C +    + C CPP +     G  C  D+ +      V+ +S 
Sbjct: 373 TNIDDC-SPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSC 427

Query: 65  TETCRDSDELSEDGTMAACC-CSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLE 121
                        G M   C  ++    G  C  D         YR +CP  PGY     
Sbjct: 428 KNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICP--PGY----- 479

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
             +      DIDECA++  L   G C N    F C C  G+S                P+
Sbjct: 480 --AGDHCERDIDECASNPCLNG-GHCQNEINRFQCLCPTGFS----GNLCQLDIDYCEPN 532

Query: 182 VCGPGV-CRNLPGSYVCLCPEGY 203
            C  G  C N    Y C CPE Y
Sbjct: 533 PCQNGAQCYNRASDYFCKCPEDY 555



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 54/205 (26%), Positives = 73/205 (35%), Gaps = 30/205 (14%)

Query: 8   DVDECKSPQSC-QYGQCINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C + Q C   G C NT    Y C CP  Y     G  C  +  A C         +
Sbjct: 296 DLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYS----GPNCEIAEHA-CL--------S 342

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGYQPVL 120
           + C +     E      C CS G  W G  C    D C  P + ++   C         +
Sbjct: 343 DPCHNRGSCKETSLGFECECSPG--WTGPTCSTNIDDC-SPNNCSHGGTCQDLVNGFKCV 399

Query: 121 EPPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            PP +      +D  EC A   + A  +C N   S+ C C  GW                
Sbjct: 400 CPPQWTGKTCQLDANECEAKPCVNAK-SCKNLIASYYCDCLPGWMGQNCDININDCLGQC 458

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
           + D      CR+L   Y C+CP GY
Sbjct: 459 QNDAS----CRDLVNGYRCICPPGY 479



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 53/201 (26%), Positives = 77/201 (38%), Gaps = 33/201 (16%)

Query: 8   DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           D+D C+ P  CQ G QC N    Y C+CP +YE    G  C    K  C         T 
Sbjct: 525 DIDYCE-PNPCQNGAQCYNRASDYFCKCPEDYE----GKNC-SHLKDHC--------RTT 570

Query: 67  TCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQL-CPGGPGYQPVLEPP 123
            C   D  +    MA+     G  +   N C P  +  S++  +  C    G+       
Sbjct: 571 PCEVIDSCTV--AMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF------- 621

Query: 124 SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +      +I++C ++   C + GTC +   S+ C C  GW  A              P  
Sbjct: 622 TGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGWEGA--YCETNINDCSQNPCH 677

Query: 183 CGPGVCRNLPGSYVCLCPEGY 203
            G G CR+L   + C C  G+
Sbjct: 678 NG-GTCRDLVNDFYCDCKNGW 697



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 36/153 (23%), Positives = 60/153 (39%), Gaps = 17/153 (11%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           PGF   +C  +++EC+S   C +G  C++    Y C CPP +     G  C +     C 
Sbjct: 810 PGFAGPDCRININECQS-SPCAFGATCVDEINGYRCVCPPGH----SGAKCQEVSGRPC- 863

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
               +  G+    D  +  +D     C     A    +C P P    + + + CP G   
Sbjct: 864 ----ITMGS-VIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSE-CPSGQSC 917

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTN 149
            P+L+   +V     + EC +         CT+
Sbjct: 918 IPILDDQCFVHPCTGVGECRSSSLQPVKTKCTS 950



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 58/218 (26%), Positives = 80/218 (36%), Gaps = 44/218 (20%)

Query: 12  CKSPQSC--QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           CK P  C  QYG     QG Y  +C P+   V     C +  +  C    +   G + C 
Sbjct: 245 CKLPGDCRCQYGW----QGLYCDKCIPHPGCVHG--ICNEPWQCLC----ETNWGGQLC- 293

Query: 70  DSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGP------ 114
           D D L+  GT   C     C + G     Y   CPE    P  E     C   P      
Sbjct: 294 DKD-LNYCGTHQPCLNGGTCSNTGP--DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGS 350

Query: 115 ------GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAP 166
                 G++    P     T + +ID+C+ +   C+HG TC +    F C C   W+   
Sbjct: 351 CKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCPPQWT--G 406

Query: 167 XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +P V     C+NL  SY C C  G++
Sbjct: 407 KTCQLDANECEAKPCVNAKS-CKNLIASYYCDCLPGWM 443



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 52/206 (25%), Positives = 75/206 (36%), Gaps = 32/206 (15%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           ++++C+S      G CI+   SY C C   +E     T   D  +  C+       GT  
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHN-----GGT-- 681

Query: 68  CRD--SDELSE--DGTMAACCCSVGA----AWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           CRD  +D   +  +G     C S  +    A  N    C + G +A++ +CPGG      
Sbjct: 682 CRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG-DAFKCMCPGGW----- 735

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                    +A    C  +   C +G TC     SF C C  GW   P            
Sbjct: 736 ---EGTTCNIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGWE-GPICAQNTNDCS-- 787

Query: 179 RPDVC-GPGVCRNLPGSYVCLCPEGY 203
            P  C   G C +    Y C C  G+
Sbjct: 788 -PHPCYNSGTCVDGDNWYRCECAPGF 812



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 1/37 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY 38
           G +C  D+DEC S      G C N    + C CP  +
Sbjct: 481 GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF 517


>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille
           syndrome) protein.
          Length = 1218

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 56/203 (27%), Positives = 76/203 (37%), Gaps = 26/203 (12%)

Query: 7   TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSG 64
           T++D+C SP +C +G  C +    + C CPP +     G  C  D+ +      V+ +S 
Sbjct: 373 TNIDDC-SPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSC 427

Query: 65  TETCRDSDELSEDGTMAACC-CSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLE 121
                        G M   C  ++    G  C  D         YR +CP  PGY     
Sbjct: 428 KNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICP--PGY----- 479

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
             +      DIDECA++  L   G C N    F C C  G+S                P+
Sbjct: 480 --AGDHCERDIDECASNPCLNG-GHCQNEINRFQCLCPTGFS----GNLCQLDIDYCEPN 532

Query: 182 VCGPGV-CRNLPGSYVCLCPEGY 203
            C  G  C N    Y C CPE Y
Sbjct: 533 PCQNGAQCYNRASDYFCKCPEDY 555



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 54/205 (26%), Positives = 73/205 (35%), Gaps = 30/205 (14%)

Query: 8   DVDECKSPQSC-QYGQCINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C + Q C   G C NT    Y C CP  Y     G  C  +  A C         +
Sbjct: 296 DLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYS----GPNCEIAEHA-CL--------S 342

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGYQPVL 120
           + C +     E      C CS G  W G  C    D C  P + ++   C         +
Sbjct: 343 DPCHNRGSCKETSLGFECECSPG--WTGPTCSTNIDDC-SPNNCSHGGTCQDLVNGFKCV 399

Query: 121 EPPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            PP +      +D  EC A   + A  +C N   S+ C C  GW                
Sbjct: 400 CPPQWTGKTCQLDANECEAKPCVNAK-SCKNLIASYYCDCLPGWMGQNCDININDCLGQC 458

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
           + D      CR+L   Y C+CP GY
Sbjct: 459 QNDAS----CRDLVNGYRCICPPGY 479



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 53/201 (26%), Positives = 77/201 (38%), Gaps = 33/201 (16%)

Query: 8   DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           D+D C+ P  CQ G QC N    Y C+CP +YE    G  C    K  C         T 
Sbjct: 525 DIDYCE-PNPCQNGAQCYNRASDYFCKCPEDYE----GKNC-SHLKDHC--------RTT 570

Query: 67  TCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQL-CPGGPGYQPVLEPP 123
            C   D  +    MA+     G  +   N C P  +  S++  +  C    G+       
Sbjct: 571 PCEVIDSCTV--AMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF------- 621

Query: 124 SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +      +I++C ++   C + GTC +   S+ C C  GW  A              P  
Sbjct: 622 TGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGWEGA--YCETNINDCSQNPCH 677

Query: 183 CGPGVCRNLPGSYVCLCPEGY 203
            G G CR+L   + C C  G+
Sbjct: 678 NG-GTCRDLVNDFYCDCKNGW 697



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 17/153 (11%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           PGF   +C  +++EC+S   C +G  C++    Y C CPP +     G  C +     C 
Sbjct: 810 PGFAGPDCRININECQS-SPCAFGATCVDEINGYRCVCPPGH----SGAKCQEVSGRPC- 863

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
               +  G+   RD  +  +D     C     A    +C P P    + + + CP G   
Sbjct: 864 ----ITMGS-VIRDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSE-CPSGQSC 917

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTN 149
            P+L+   +V     + EC +         CT+
Sbjct: 918 IPILDDQCFVHPCTGVGECRSSSLQPVKTKCTS 950



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 58/218 (26%), Positives = 80/218 (36%), Gaps = 44/218 (20%)

Query: 12  CKSPQSC--QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           CK P  C  QYG     QG Y  +C P+   V     C +  +  C    +   G + C 
Sbjct: 245 CKLPGDCRCQYGW----QGLYCDKCIPHPGCVHG--ICNEPWQCLC----ETNWGGQLC- 293

Query: 70  DSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGP------ 114
           D D L+  GT   C     C + G     Y   CPE    P  E     C   P      
Sbjct: 294 DKD-LNYCGTHQPCLNGGTCSNTGP--DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGS 350

Query: 115 ------GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAP 166
                 G++    P     T + +ID+C+ +   C+HG TC +    F C C   W+   
Sbjct: 351 CKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCPPQWT--G 406

Query: 167 XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +P V     C+NL  SY C C  G++
Sbjct: 407 KTCQLDANECEAKPCVNAKS-CKNLIASYYCDCLPGWM 443



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 52/206 (25%), Positives = 75/206 (36%), Gaps = 32/206 (15%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           ++++C+S      G CI+   SY C C   +E     T   D  +  C+       GT  
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHN-----GGT-- 681

Query: 68  CRD--SDELSE--DGTMAACCCSVGA----AWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           CRD  +D   +  +G     C S  +    A  N    C + G +A++ +CPGG      
Sbjct: 682 CRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG-DAFKCMCPGGW----- 735

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                    +A    C  +   C +G TC     SF C C  GW   P            
Sbjct: 736 ---EGTTCNIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGWE-GPICAQNTNDCS-- 787

Query: 179 RPDVC-GPGVCRNLPGSYVCLCPEGY 203
            P  C   G C +    Y C C  G+
Sbjct: 788 -PHPCYNSGTCVDGDNWYRCECAPGF 812



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 1/37 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY 38
           G +C  D+DEC S      G C N    + C CP  +
Sbjct: 481 GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF 517


>AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille
           syndrome) protein.
          Length = 1218

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 56/203 (27%), Positives = 76/203 (37%), Gaps = 26/203 (12%)

Query: 7   TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSG 64
           T++D+C SP +C +G  C +    + C CPP +     G  C  D+ +      V+ +S 
Sbjct: 373 TNIDDC-SPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSC 427

Query: 65  TETCRDSDELSEDGTMAACC-CSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLE 121
                        G M   C  ++    G  C  D         YR +CP  PGY     
Sbjct: 428 KNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICP--PGY----- 479

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
             +      DIDECA++  L   G C N    F C C  G+S                P+
Sbjct: 480 --AGDHCERDIDECASNPCLNG-GHCQNEINRFQCLCPTGFS----GNLCQLDIDYCEPN 532

Query: 182 VCGPGV-CRNLPGSYVCLCPEGY 203
            C  G  C N    Y C CPE Y
Sbjct: 533 PCQNGAQCYNRASDYFCKCPEDY 555



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 54/205 (26%), Positives = 73/205 (35%), Gaps = 30/205 (14%)

Query: 8   DVDECKSPQSC-QYGQCINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C + Q C   G C NT    Y C CP  Y     G  C  +  A C         +
Sbjct: 296 DLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYS----GPNCEIAEHA-CL--------S 342

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGYQPVL 120
           + C +     E      C CS G  W G  C    D C  P + ++   C         +
Sbjct: 343 DPCHNRGSCKETSLGFECECSPG--WTGPTCSTNIDDC-SPNNCSHGGTCQDLVNGFKCV 399

Query: 121 EPPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            PP +      +D  EC A   + A  +C N   S+ C C  GW                
Sbjct: 400 CPPQWTGKTCQLDANECEAKPCVNAK-SCKNLIASYYCDCLPGWMGQNCDININDCLGQC 458

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
           + D      CR+L   Y C+CP GY
Sbjct: 459 QNDAS----CRDLVNGYRCICPPGY 479



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 53/201 (26%), Positives = 77/201 (38%), Gaps = 33/201 (16%)

Query: 8   DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           D+D C+ P  CQ G QC N    Y C+CP +YE    G  C    K  C         T 
Sbjct: 525 DIDYCE-PNPCQNGAQCYNRASDYFCKCPEDYE----GKNC-SHLKDHC--------RTT 570

Query: 67  TCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQL-CPGGPGYQPVLEPP 123
            C   D  +    MA+     G  +   N C P  +  S++  +  C    G+       
Sbjct: 571 PCEVIDSCTV--AMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF------- 621

Query: 124 SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +      +I++C ++   C + GTC +   S+ C C  GW  A              P  
Sbjct: 622 TGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGWEGA--YCETNINDCSQNPCH 677

Query: 183 CGPGVCRNLPGSYVCLCPEGY 203
            G G CR+L   + C C  G+
Sbjct: 678 NG-GTCRDLVNDFYCDCKNGW 697



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 36/153 (23%), Positives = 60/153 (39%), Gaps = 17/153 (11%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           PGF   +C  +++EC+S   C +G  C++    Y C CPP +     G  C +     C 
Sbjct: 810 PGFAGPDCRININECQS-SPCAFGATCVDEINGYRCVCPPGH----SGAKCQEVSGRPC- 863

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
               +  G+    D  +  +D     C     A    +C P P    + + + CP G   
Sbjct: 864 ----ITMGS-VIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSE-CPSGQSC 917

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTN 149
            P+L+   +V     + EC +         CT+
Sbjct: 918 IPILDDQCFVHPCTGVGECRSSSLQPVKTKCTS 950



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 58/218 (26%), Positives = 80/218 (36%), Gaps = 44/218 (20%)

Query: 12  CKSPQSC--QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           CK P  C  QYG     QG Y  +C P+   V     C +  +  C    +   G + C 
Sbjct: 245 CKLPGDCRCQYGW----QGLYCDKCIPHPGCVHG--ICNEPWQCLC----ETNWGGQLC- 293

Query: 70  DSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGP------ 114
           D D L+  GT   C     C + G     Y   CPE    P  E     C   P      
Sbjct: 294 DKD-LNYCGTHQPCLNGGTCSNTGP--DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGS 350

Query: 115 ------GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAP 166
                 G++    P     T + +ID+C+ +   C+HG TC +    F C C   W+   
Sbjct: 351 CKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCPPQWT--G 406

Query: 167 XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +P V     C+NL  SY C C  G++
Sbjct: 407 KTCQLDANECEAKPCVNAKS-CKNLIASYYCDCLPGWM 443



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 52/206 (25%), Positives = 75/206 (36%), Gaps = 32/206 (15%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           ++++C+S      G CI+   SY C C   +E     T   D  +  C+       GT  
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHN-----GGT-- 681

Query: 68  CRD--SDELSE--DGTMAACCCSVGA----AWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           CRD  +D   +  +G     C S  +    A  N    C + G +A++ +CPGG      
Sbjct: 682 CRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG-DAFKCMCPGGW----- 735

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                    +A    C  +   C +G TC     SF C C  GW   P            
Sbjct: 736 ---EGTTCNIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGWE-GPICAQNTNDCS-- 787

Query: 179 RPDVC-GPGVCRNLPGSYVCLCPEGY 203
            P  C   G C +    Y C C  G+
Sbjct: 788 -PHPCYNSGTCVDGDNWYRCECAPGF 812



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 1/37 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY 38
           G +C  D+DEC S      G C N    + C CP  +
Sbjct: 481 GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF 517


>AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein
           Jagged 1 protein.
          Length = 1218

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 56/203 (27%), Positives = 76/203 (37%), Gaps = 26/203 (12%)

Query: 7   TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSG 64
           T++D+C SP +C +G  C +    + C CPP +     G  C  D+ +      V+ +S 
Sbjct: 373 TNIDDC-SPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSC 427

Query: 65  TETCRDSDELSEDGTMAACC-CSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLE 121
                        G M   C  ++    G  C  D         YR +CP  PGY     
Sbjct: 428 KNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICP--PGY----- 479

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
             +      DIDECA++  L   G C N    F C C  G+S                P+
Sbjct: 480 --AGDHCERDIDECASNPCLNG-GHCQNEINRFQCLCPTGFS----GNLCQLDIDYCEPN 532

Query: 182 VCGPGV-CRNLPGSYVCLCPEGY 203
            C  G  C N    Y C CPE Y
Sbjct: 533 PCQNGAQCYNRASDYFCKCPEDY 555



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 54/205 (26%), Positives = 73/205 (35%), Gaps = 30/205 (14%)

Query: 8   DVDECKSPQSC-QYGQCINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C + Q C   G C NT    Y C CP  Y     G  C  +  A C         +
Sbjct: 296 DLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYS----GPNCEIAEHA-CL--------S 342

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGYQPVL 120
           + C +     E      C CS G  W G  C    D C  P + ++   C         +
Sbjct: 343 DPCHNRGSCKETSLGFECECSPG--WTGPTCSTNIDDC-SPNNCSHGGTCQDLVNGFKCV 399

Query: 121 EPPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            PP +      +D  EC A   + A  +C N   S+ C C  GW                
Sbjct: 400 CPPQWTGKTCQLDANECEAKPCVNAK-SCKNLIASYYCDCLPGWMGQNCDININDCLGQC 458

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
           + D      CR+L   Y C+CP GY
Sbjct: 459 QNDAS----CRDLVNGYRCICPPGY 479



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 53/201 (26%), Positives = 77/201 (38%), Gaps = 33/201 (16%)

Query: 8   DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           D+D C+ P  CQ G QC N    Y C+CP +YE    G  C    K  C         T 
Sbjct: 525 DIDYCE-PNPCQNGAQCYNRASDYFCKCPEDYE----GKNC-SHLKDHC--------RTT 570

Query: 67  TCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQL-CPGGPGYQPVLEPP 123
            C   D  +    MA+     G  +   N C P  +  S++  +  C    G+       
Sbjct: 571 PCEVIDSCTV--AMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF------- 621

Query: 124 SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +      +I++C ++   C + GTC +   S+ C C  GW  A              P  
Sbjct: 622 TGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGWEGA--YCETNINDCSQNPCH 677

Query: 183 CGPGVCRNLPGSYVCLCPEGY 203
            G G CR+L   + C C  G+
Sbjct: 678 NG-GTCRDLVNDFYCDCKNGW 697



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 36/153 (23%), Positives = 60/153 (39%), Gaps = 17/153 (11%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           PGF   +C  +++EC+S   C +G  C++    Y C CPP +     G  C +     C 
Sbjct: 810 PGFAGPDCRININECQS-SPCAFGATCVDEINGYRCVCPPGH----SGAKCQEVSGRPC- 863

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
               +  G+    D  +  +D     C     A    +C P P    + + + CP G   
Sbjct: 864 ----ITMGS-VIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSE-CPSGQSC 917

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTN 149
            P+L+   +V     + EC +         CT+
Sbjct: 918 IPILDDQCFVHPCTGVGECRSSSLQPVKTKCTS 950



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 58/218 (26%), Positives = 80/218 (36%), Gaps = 44/218 (20%)

Query: 12  CKSPQSC--QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           CK P  C  QYG     QG Y  +C P+   V     C +  +  C    +   G + C 
Sbjct: 245 CKLPGDCRCQYGW----QGLYCDKCIPHPGCVHG--ICNEPWQCLC----ETNWGGQLC- 293

Query: 70  DSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGP------ 114
           D D L+  GT   C     C + G     Y   CPE    P  E     C   P      
Sbjct: 294 DKD-LNYCGTHQPCLNGGTCSNTGP--DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGS 350

Query: 115 ------GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAP 166
                 G++    P     T + +ID+C+ +   C+HG TC +    F C C   W+   
Sbjct: 351 CKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCPPQWT--G 406

Query: 167 XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +P V     C+NL  SY C C  G++
Sbjct: 407 KTCQLDANECEAKPCVNAKS-CKNLIASYYCDCLPGWM 443



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 52/206 (25%), Positives = 75/206 (36%), Gaps = 32/206 (15%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           ++++C+S      G CI+   SY C C   +E     T   D  +  C+       GT  
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHN-----GGT-- 681

Query: 68  CRD--SDELSE--DGTMAACCCSVGA----AWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           CRD  +D   +  +G     C S  +    A  N    C + G +A++ +CPGG      
Sbjct: 682 CRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG-DAFKCMCPGGW----- 735

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                    +A    C  +   C +G TC     SF C C  GW   P            
Sbjct: 736 ---EGTTCNIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGWE-GPICAQNTNDCS-- 787

Query: 179 RPDVC-GPGVCRNLPGSYVCLCPEGY 203
            P  C   G C +    Y C C  G+
Sbjct: 788 -PHPCYNSGTCVDGDNWYRCECAPGF 812



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 1/37 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY 38
           G +C  D+DEC S      G C N    + C CP  +
Sbjct: 481 GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF 517


>AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.
          Length = 1218

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 56/203 (27%), Positives = 76/203 (37%), Gaps = 26/203 (12%)

Query: 7   TDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACY-DSRKARCYGKVDLRSG 64
           T++D+C SP +C +G  C +    + C CPP +     G  C  D+ +      V+ +S 
Sbjct: 373 TNIDDC-SPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKSC 427

Query: 65  TETCRDSDELSEDGTMAACC-CSVGAAWGNYC--DPCPEPGSEAYRQLCPGGPGYQPVLE 121
                        G M   C  ++    G  C  D         YR +CP  PGY     
Sbjct: 428 KNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICP--PGY----- 479

Query: 122 PPSYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD 181
             +      DIDECA++  L   G C N    F C C  G+S                P+
Sbjct: 480 --AGDHCERDIDECASNPCLDG-GHCQNEINRFQCLCPTGFS----GNLCQLDIDYCEPN 532

Query: 182 VCGPGV-CRNLPGSYVCLCPEGY 203
            C  G  C N    Y C CPE Y
Sbjct: 533 PCQNGAQCYNRASDYFCKCPEDY 555



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 54/205 (26%), Positives = 73/205 (35%), Gaps = 30/205 (14%)

Query: 8   DVDECKSPQSC-QYGQCINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C + Q C   G C NT    Y C CP  Y     G  C  +  A C         +
Sbjct: 296 DLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYS----GPNCEIAEHA-CL--------S 342

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAW-GNYC----DPCPEPGSEAYRQLCPGGPGYQPVL 120
           + C +     E      C CS G  W G  C    D C  P + ++   C         +
Sbjct: 343 DPCHNRGSCKETSLGFECECSPG--WTGPTCSTNIDDC-SPNNCSHGGTCQDLVNGFKCV 399

Query: 121 EPPSYVVTLADID--ECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
            PP +      +D  EC A   + A  +C N   S+ C C  GW                
Sbjct: 400 CPPQWTGKTCQLDANECEAKPCVNAK-SCKNLIASYYCDCLPGWMGQNCDININDCLGQC 458

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGY 203
           + D      CR+L   Y C+CP GY
Sbjct: 459 QNDAS----CRDLVNGYRCICPPGY 479



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 53/201 (26%), Positives = 77/201 (38%), Gaps = 33/201 (16%)

Query: 8   DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           D+D C+ P  CQ G QC N    Y C+CP +YE    G  C    K  C         T 
Sbjct: 525 DIDYCE-PNPCQNGAQCYNRASDYFCKCPEDYE----GKNC-SHLKDHC--------RTT 570

Query: 67  TCRDSDELSEDGTMAACCCSVGAAW--GNYCDPCPEPGSEAYRQL-CPGGPGYQPVLEPP 123
            C   D  +    MA+     G  +   N C P  +  S++  +  C    G+       
Sbjct: 571 PCEVIDSCTV--AMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF------- 621

Query: 124 SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDV 182
           +      +I++C ++   C + GTC +   S+ C C  GW  A              P  
Sbjct: 622 TGTYCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGWEGA--YCETNINDCSQNPCH 677

Query: 183 CGPGVCRNLPGSYVCLCPEGY 203
            G G CR+L   + C C  G+
Sbjct: 678 NG-GTCRDLVNDFYCDCKNGW 697



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 36/153 (23%), Positives = 60/153 (39%), Gaps = 17/153 (11%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCY 56
           PGF   +C  +++EC+S   C +G  C++    Y C CPP +     G  C +     C 
Sbjct: 810 PGFAGPDCRININECQS-SPCAFGATCVDEINGYRCVCPPGH----SGAKCQEVSGRPC- 863

Query: 57  GKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGY 116
               +  G+    D  +  +D     C     A    +C P P    + + + CP G   
Sbjct: 864 ----ITMGS-VIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSE-CPSGQSC 917

Query: 117 QPVLEPPSYVVTLADIDECAAHEGLCAHGTCTN 149
            P+L+   +V     + EC +         CT+
Sbjct: 918 IPILDDQCFVHPCTGVGECRSSSLQPVKTKCTS 950



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 58/218 (26%), Positives = 80/218 (36%), Gaps = 44/218 (20%)

Query: 12  CKSPQSC--QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCR 69
           CK P  C  QYG     QG Y  +C P+   V     C +  +  C    +   G + C 
Sbjct: 245 CKLPGDCRCQYGW----QGLYCDKCIPHPGCVHG--ICNEPWQCLC----ETNWGGQLC- 293

Query: 70  DSDELSEDGTMAAC-----CCSVGAAWGNYCDPCPE----PGSEAYRQLCPGGP------ 114
           D D L+  GT   C     C + G     Y   CPE    P  E     C   P      
Sbjct: 294 DKD-LNYCGTHQPCLNGGTCSNTGP--DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGS 350

Query: 115 ------GYQPVLEPPSYVVTLA-DIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAP 166
                 G++    P     T + +ID+C+ +   C+HG TC +    F C C   W+   
Sbjct: 351 CKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCPPQWT--G 406

Query: 167 XXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGYV 204
                       +P V     C+NL  SY C C  G++
Sbjct: 407 KTCQLDANECEAKPCVNAKS-CKNLIASYYCDCLPGWM 443



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 52/206 (25%), Positives = 75/206 (36%), Gaps = 32/206 (15%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           ++++C+S      G CI+   SY C C   +E     T   D  +  C+       GT  
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHN-----GGT-- 681

Query: 68  CRD--SDELSE--DGTMAACCCSVGA----AWGNYCDPCPEPGSEAYRQLCPGGPGYQPV 119
           CRD  +D   +  +G     C S  +    A  N    C + G +A++ +CPGG      
Sbjct: 682 CRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG-DAFKCMCPGGW----- 735

Query: 120 LEPPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXX 178
                    +A    C  +   C +G TC     SF C C  GW   P            
Sbjct: 736 ---EGTTCNIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGWE-GPICAQNTNDCS-- 787

Query: 179 RPDVC-GPGVCRNLPGSYVCLCPEGY 203
            P  C   G C +    Y C C  G+
Sbjct: 788 -PHPCYNSGTCVDGDNWYRCECAPGF 812



 Score = 30.3 bits (65), Expect = 5.9
 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 1/37 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNY 38
           G +C  D+DEC S      G C N    + C CP  +
Sbjct: 481 GDHCERDIDECASNPCLDGGHCQNEINRFQCLCPTGF 517


>BC035784-1|AAH35784.1|  439|Homo sapiens hypothetical protein
           FLJ37440 protein.
          Length = 439

 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 52/173 (30%), Positives = 68/173 (39%), Gaps = 30/173 (17%)

Query: 5   NCTDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTAC-YDSRKARCYGKVDLR 62
           +C  + EC S Q CQ G  C+     Y C CPP       G  C + ++ A   G V   
Sbjct: 133 HCRGISECSS-QPCQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQTAAPEGSV--- 184

Query: 63  SGTETCRDSDELSEDGTMAACCCSV-----GAAWGNYC---DPCPEPGSEAYRQL----C 110
           +G      +   ++      C C       GAA  + C   + C   G E   +L    C
Sbjct: 185 AGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHAC 244

Query: 111 PGGPGYQPVLEPPSYVVTLA------DIDECAAHEGLCAHG-TCTNTFGSFVC 156
              PG      P  Y  TLA      D+DEC   + +C  G TC NT GSF C
Sbjct: 245 VNTPGSYRCTCPGGY-RTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 31/82 (37%), Positives = 39/82 (47%), Gaps = 11/82 (13%)

Query: 131 DIDECAAH--EG---LCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCG 184
           D++EC  +  EG   LC H  C NT GS+ CTC  G+ +LA                VC 
Sbjct: 224 DVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCP 282

Query: 185 PG-VCRNLPGSYVCL---CPEG 202
            G  C N  GS+ C+   CPEG
Sbjct: 283 QGTTCINTGGSFQCVSPECPEG 304



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 1/31 (3%)

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           RP +C    C N PGSY C CP GY  + +G
Sbjct: 236 RPRLC-MHACVNTPGSYRCTCPGGYRTLADG 265



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 18/35 (51%), Positives = 20/35 (57%), Gaps = 2/35 (5%)

Query: 3   GFNCTDVDECKSPQS-CQYGQ-CINTQGSYTCRCP 35
           G +C DVDEC   Q  C  G  CINT GS+ C  P
Sbjct: 265 GKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSP 299


>AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 1294

 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 48/168 (28%), Positives = 63/168 (37%), Gaps = 28/168 (16%)

Query: 8   DVDECKSP---QSCQ-YGQCINTQG--SYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           D D  K P     CQ    C+NT G  S+ C+CPP Y     GT C ++    C      
Sbjct: 66  DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY----SGTIC-ETTIGSC------ 114

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQ 117
             G  +C+      +D     C C  G A G +C    D C     +       G  GY 
Sbjct: 115 --GKNSCQHGGICHQDPIYPVCICPAGYA-GRFCEIDHDECASSPCQNGAVCQDGIDGYS 171

Query: 118 PVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS 163
                P Y     D  +DECA+ +      TC N  G + C C   +S
Sbjct: 172 -CFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEIGRYTCICPHNYS 217



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 43/160 (26%), Positives = 67/160 (41%), Gaps = 32/160 (20%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  +VDEC S        C+N  G YTC CP NY   + G  C          ++DL
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGYT-GAQC----------EIDL 228

Query: 62  RS-GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
               +  C+ + E  E         S    +G        P S +Y +      GY  + 
Sbjct: 229 NECNSNPCQSNGECVE--------LSSEKQYGRITG---LPSSFSYHE----ASGYVCIC 273

Query: 121 EPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTC 158
           +P  + +    D++EC+++   C + GTC N  G++ C C
Sbjct: 274 QPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHC 311



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 10/96 (10%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC  D+D C+S Q      CI+    Y+C C  N+     G  C   R++R    V  
Sbjct: 1096 GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNF----TGKFC---RQSRLPSTVCG 1148

Query: 62   RSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
               T  TC +    +E  T   C C  G   G +C+
Sbjct: 1149 NEKTNLTCYNGGNCTEFQTELKCMCRPGFT-GEWCE 1183



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCP 35
           G +C  DV+EC S      G C N  G+YTC CP
Sbjct: 279 GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 312



 Score = 34.3 bits (75), Expect = 0.36
 Identities = 23/97 (23%), Positives = 31/97 (31%), Gaps = 6/97 (6%)

Query: 109 LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPX 167
           +C   P Y   + P  Y     +ID        C +G  C +    + C C  G+     
Sbjct: 124 ICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ---- 179

Query: 168 XXXXXXXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                        D C     C N  G Y C+CP  Y
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNY 216



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 142  CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
            C HG  C + + S+ C+C  GWS                P  C  G C +   +Y C C 
Sbjct: 1036 CLHGGNCEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCE 1091

Query: 201  EGYVAM 206
             GY  +
Sbjct: 1092 PGYTGV 1097



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 44/175 (25%), Positives = 66/175 (37%), Gaps = 31/175 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C  ++DEC S   C +G C +   +Y C C P Y  V+      + +  +C      
Sbjct: 1059 GKHCELNIDECFS-NPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQC------ 1111

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPG-- 115
             +   TC     +S   T    C   G   G +C     P    G+E     C  G    
Sbjct: 1112 -ANGATC-----ISH--TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1163

Query: 116  -YQPVLE---PPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS 163
             +Q  L+    P +       DIDECA+    C + G C +    F C C   ++
Sbjct: 1164 EFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFA 1216



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 5/60 (8%)

Query: 146 TCTNTFG--SFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
           TC NT G  SF+C C  G+S               +      G+C   P   VC+CP GY
Sbjct: 84  TCVNTPGERSFLCKCPPGYS---GTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGY 140



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 10/15 (66%), Positives = 11/15 (73%)

Query: 186 GVCRNLPGSYVCLCP 200
           G C NLPG+Y C CP
Sbjct: 298 GTCENLPGNYTCHCP 312



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 2/35 (5%)

Query: 6   CTDVDECKSPQSCQY-GQCINTQGSYTCRCPPNYE 39
           C   D C+S Q CQ  G+CIN   SY C C   YE
Sbjct: 558 CVRKDWCES-QPCQSRGRCINLWLSYQCDCHRPYE 591


>AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 1294

 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 48/168 (28%), Positives = 63/168 (37%), Gaps = 28/168 (16%)

Query: 8   DVDECKSP---QSCQ-YGQCINTQG--SYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           D D  K P     CQ    C+NT G  S+ C+CPP Y     GT C ++    C      
Sbjct: 66  DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY----SGTIC-ETTIGSC------ 114

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQ 117
             G  +C+      +D     C C  G A G +C    D C     +       G  GY 
Sbjct: 115 --GKNSCQHGGICHQDPIYPVCICPAGYA-GRFCEIDHDECASSPCQNGAVCQDGIDGYS 171

Query: 118 PVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS 163
                P Y     D  +DECA+ +      TC N  G + C C   +S
Sbjct: 172 -CFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEIGRYTCICPHNYS 217



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 43/160 (26%), Positives = 67/160 (41%), Gaps = 32/160 (20%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  +VDEC S        C+N  G YTC CP NY   + G  C          ++DL
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGYT-GAQC----------EIDL 228

Query: 62  RS-GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
               +  C+ + E  E         S    +G        P S +Y +      GY  + 
Sbjct: 229 NECNSNPCQSNGECVE--------LSSEKQYGRITG---LPSSFSYHE----ASGYVCIC 273

Query: 121 EPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTC 158
           +P  + +    D++EC+++   C + GTC N  G++ C C
Sbjct: 274 QPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHC 311



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 10/96 (10%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC  D+D C+S Q      CI+    Y+C C  N+     G  C   R++R    V  
Sbjct: 1096 GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNF----TGKFC---RQSRLPSTVCG 1148

Query: 62   RSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
               T  TC +    +E  T   C C  G   G +C+
Sbjct: 1149 NEKTNLTCYNGGNCTEFQTELKCMCRPGFT-GEWCE 1183



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCP 35
           G +C  DV+EC S      G C N  G+YTC CP
Sbjct: 279 GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 312



 Score = 34.3 bits (75), Expect = 0.36
 Identities = 23/97 (23%), Positives = 31/97 (31%), Gaps = 6/97 (6%)

Query: 109 LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPX 167
           +C   P Y   + P  Y     +ID        C +G  C +    + C C  G+     
Sbjct: 124 ICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ---- 179

Query: 168 XXXXXXXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                        D C     C N  G Y C+CP  Y
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNY 216



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 142  CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
            C HG  C + + S+ C+C  GWS                P  C  G C +   +Y C C 
Sbjct: 1036 CLHGGNCEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCE 1091

Query: 201  EGYVAM 206
             GY  +
Sbjct: 1092 PGYTGV 1097



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 44/175 (25%), Positives = 66/175 (37%), Gaps = 31/175 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C  ++DEC S   C +G C +   +Y C C P Y  V+      + +  +C      
Sbjct: 1059 GKHCELNIDECFS-NPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQC------ 1111

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPG-- 115
             +   TC     +S   T    C   G   G +C     P    G+E     C  G    
Sbjct: 1112 -ANGATC-----ISH--TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1163

Query: 116  -YQPVLE---PPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS 163
             +Q  L+    P +       DIDECA+    C + G C +    F C C   ++
Sbjct: 1164 EFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFA 1216



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 5/60 (8%)

Query: 146 TCTNTFG--SFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
           TC NT G  SF+C C  G+S               +      G+C   P   VC+CP GY
Sbjct: 84  TCVNTPGERSFLCKCPPGYS---GTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGY 140



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 10/15 (66%), Positives = 11/15 (73%)

Query: 186 GVCRNLPGSYVCLCP 200
           G C NLPG+Y C CP
Sbjct: 298 GTCENLPGNYTCHCP 312



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 2/35 (5%)

Query: 6   CTDVDECKSPQSCQY-GQCINTQGSYTCRCPPNYE 39
           C   D C+S Q CQ  G+CIN   SY C C   YE
Sbjct: 558 CVRKDWCES-QPCQSRGRCINLWLSYQCDCHRPYE 591


>AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 1294

 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 48/168 (28%), Positives = 63/168 (37%), Gaps = 28/168 (16%)

Query: 8   DVDECKSP---QSCQ-YGQCINTQG--SYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           D D  K P     CQ    C+NT G  S+ C+CPP Y     GT C ++    C      
Sbjct: 66  DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY----SGTIC-ETTIGSC------ 114

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQ 117
             G  +C+      +D     C C  G A G +C    D C     +       G  GY 
Sbjct: 115 --GKNSCQHGGICHQDPIYPVCICPAGYA-GRFCEIDHDECASSPCQNGAVCQDGIDGYS 171

Query: 118 PVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS 163
                P Y     D  +DECA+ +      TC N  G + C C   +S
Sbjct: 172 -CFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEIGRYTCICPHNYS 217



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 43/160 (26%), Positives = 67/160 (41%), Gaps = 32/160 (20%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  +VDEC S        C+N  G YTC CP NY   + G  C          ++DL
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGYT-GAQC----------EIDL 228

Query: 62  RS-GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
               +  C+ + E  E         S    +G        P S +Y +      GY  + 
Sbjct: 229 NECNSNPCQSNGECVE--------LSSEKQYGRITG---LPSSFSYHE----ASGYVCIC 273

Query: 121 EPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTC 158
           +P  + +    D++EC+++   C + GTC N  G++ C C
Sbjct: 274 QPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHC 311



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 10/96 (10%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC  D+D C+S Q      CI+    Y+C C  N+     G  C   R++R    V  
Sbjct: 1096 GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNF----TGKFC---RQSRLPSTVCG 1148

Query: 62   RSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
               T  TC +    +E  T   C C  G   G +C+
Sbjct: 1149 NEKTNLTCYNGGNCTEFQTELKCMCRPGFT-GEWCE 1183



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCP 35
           G +C  DV+EC S      G C N  G+YTC CP
Sbjct: 279 GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 312



 Score = 34.3 bits (75), Expect = 0.36
 Identities = 23/97 (23%), Positives = 31/97 (31%), Gaps = 6/97 (6%)

Query: 109 LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPX 167
           +C   P Y   + P  Y     +ID        C +G  C +    + C C  G+     
Sbjct: 124 ICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ---- 179

Query: 168 XXXXXXXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                        D C     C N  G Y C+CP  Y
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNY 216



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 142  CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
            C HG  C + + S+ C+C  GWS                P  C  G C +   +Y C C 
Sbjct: 1036 CLHGGNCEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCE 1091

Query: 201  EGYVAM 206
             GY  +
Sbjct: 1092 PGYTGV 1097



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 44/175 (25%), Positives = 66/175 (37%), Gaps = 31/175 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C  ++DEC S   C +G C +   +Y C C P Y  V+      + +  +C      
Sbjct: 1059 GKHCELNIDECFS-NPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQC------ 1111

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPG-- 115
             +   TC     +S   T    C   G   G +C     P    G+E     C  G    
Sbjct: 1112 -ANGATC-----ISH--TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1163

Query: 116  -YQPVLE---PPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS 163
             +Q  L+    P +       DIDECA+    C + G C +    F C C   ++
Sbjct: 1164 EFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFA 1216



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 5/60 (8%)

Query: 146 TCTNTFG--SFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
           TC NT G  SF+C C  G+S               +      G+C   P   VC+CP GY
Sbjct: 84  TCVNTPGERSFLCKCPPGYS---GTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGY 140



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 10/15 (66%), Positives = 11/15 (73%)

Query: 186 GVCRNLPGSYVCLCP 200
           G C NLPG+Y C CP
Sbjct: 298 GTCENLPGNYTCHCP 312



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 2/35 (5%)

Query: 6   CTDVDECKSPQSCQY-GQCINTQGSYTCRCPPNYE 39
           C   D C+S Q CQ  G+CIN   SY C C   YE
Sbjct: 558 CVRKDWCES-QPCQSRGRCINLWLSYQCDCHRPYE 591


>AK094759-1|BAC04416.1|  439|Homo sapiens protein ( Homo sapiens
           cDNA FLJ37440 fis, clone BRAWH2006405, weakly similar to
           FIBULIN-1, ISOFORM C PRECURSOR. ).
          Length = 439

 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 52/173 (30%), Positives = 68/173 (39%), Gaps = 30/173 (17%)

Query: 5   NCTDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTAC-YDSRKARCYGKVDLR 62
           +C  + EC S Q CQ G  C+     Y C CPP       G  C + ++ A   G V   
Sbjct: 133 HCRGISECSS-QPCQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQTAAPEGSV--- 184

Query: 63  SGTETCRDSDELSEDGTMAACCCSV-----GAAWGNYC---DPCPEPGSEAYRQL----C 110
           +G      +   ++      C C       GAA  + C   + C   G E   +L    C
Sbjct: 185 AGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHAC 244

Query: 111 PGGPGYQPVLEPPSYVVTLA------DIDECAAHEGLCAHG-TCTNTFGSFVC 156
              PG      P  Y  TLA      D+DEC   + +C  G TC NT GSF C
Sbjct: 245 VNTPGSYRCTCPGGY-RTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 31/82 (37%), Positives = 39/82 (47%), Gaps = 11/82 (13%)

Query: 131 DIDECAAH--EG---LCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCG 184
           D++EC  +  EG   LC H  C NT GS+ CTC  G+ +LA                VC 
Sbjct: 224 DVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCP 282

Query: 185 PG-VCRNLPGSYVCL---CPEG 202
            G  C N  GS+ C+   CPEG
Sbjct: 283 QGTTCINTGGSFQCVSPECPEG 304



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 1/31 (3%)

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           RP +C    C N PGSY C CP GY  + +G
Sbjct: 236 RPRLC-MHACVNTPGSYRCTCPGGYRTLADG 265



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 18/35 (51%), Positives = 20/35 (57%), Gaps = 2/35 (5%)

Query: 3   GFNCTDVDECKSPQS-CQYGQ-CINTQGSYTCRCP 35
           G +C DVDEC   Q  C  G  CINT GS+ C  P
Sbjct: 265 GKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSP 299


>AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1
           (alternative protein) protein.
          Length = 1294

 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 48/168 (28%), Positives = 63/168 (37%), Gaps = 28/168 (16%)

Query: 8   DVDECKSP---QSCQ-YGQCINTQG--SYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           D D  K P     CQ    C+NT G  S+ C+CPP Y     GT C ++    C      
Sbjct: 66  DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY----SGTIC-ETTIGSC------ 114

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAYRQLCPGGPGYQ 117
             G  +C+      +D     C C  G A G +C    D C     +       G  GY 
Sbjct: 115 --GKNSCQHGGICHQDPIYPVCICPAGYA-GRFCEIDHDECASSPCQNGAVCQDGIDGYS 171

Query: 118 PVLEPPSYVVTLAD--IDECAAHEGLCAHGTCTNTFGSFVCTCGAGWS 163
                P Y     D  +DECA+ +      TC N  G + C C   +S
Sbjct: 172 -CFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEIGRYTCICPHNYS 217



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 43/160 (26%), Positives = 67/160 (41%), Gaps = 32/160 (20%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  +VDEC S        C+N  G YTC CP NY   + G  C          ++DL
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGYT-GAQC----------EIDL 228

Query: 62  RS-GTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
               +  C+ + E  E         S    +G        P S +Y +      GY  + 
Sbjct: 229 NECNSNPCQSNGECVE--------LSSEKQYGRITG---LPSSFSYHE----ASGYVCIC 273

Query: 121 EPP-SYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTC 158
           +P  + +    D++EC+++   C + GTC N  G++ C C
Sbjct: 274 QPGFTGIHCEEDVNECSSNP--CQNGGTCENLPGNYTCHC 311



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 10/96 (10%)

Query: 3    GFNC-TDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G NC  D+D C+S Q      CI+    Y+C C  N+     G  C   R++R    V  
Sbjct: 1096 GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNF----TGKFC---RQSRLPSTVCG 1148

Query: 62   RSGTE-TCRDSDELSEDGTMAACCCSVGAAWGNYCD 96
               T  TC +    +E  T   C C  G   G +C+
Sbjct: 1149 NEKTNLTCYNGGNCTEFQTELKCMCRPGFT-GEWCE 1183



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCP 35
           G +C  DV+EC S      G C N  G+YTC CP
Sbjct: 279 GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 312



 Score = 34.3 bits (75), Expect = 0.36
 Identities = 23/97 (23%), Positives = 31/97 (31%), Gaps = 6/97 (6%)

Query: 109 LCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLAPX 167
           +C   P Y   + P  Y     +ID        C +G  C +    + C C  G+     
Sbjct: 124 ICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQ---- 179

Query: 168 XXXXXXXXXXXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
                        D C     C N  G Y C+CP  Y
Sbjct: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNY 216



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 142  CAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCP 200
            C HG  C + + S+ C+C  GWS                P  C  G C +   +Y C C 
Sbjct: 1036 CLHGGNCEDIYSSYHCSCPLGWS--GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCE 1091

Query: 201  EGYVAM 206
             GY  +
Sbjct: 1092 PGYTGV 1097



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 44/175 (25%), Positives = 66/175 (37%), Gaps = 31/175 (17%)

Query: 3    GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
            G +C  ++DEC S   C +G C +   +Y C C P Y  V+      + +  +C      
Sbjct: 1059 GKHCELNIDECFS-NPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQC------ 1111

Query: 62   RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCD----PCPEPGSEAYRQLCPGGPG-- 115
             +   TC     +S   T    C   G   G +C     P    G+E     C  G    
Sbjct: 1112 -ANGATC-----ISH--TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1163

Query: 116  -YQPVLE---PPSYVVTLA--DIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWS 163
             +Q  L+    P +       DIDECA+    C + G C +    F C C   ++
Sbjct: 1164 EFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFA 1216



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 5/60 (8%)

Query: 146 TCTNTFG--SFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
           TC NT G  SF+C C  G+S               +      G+C   P   VC+CP GY
Sbjct: 84  TCVNTPGERSFLCKCPPGYS---GTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGY 140



 Score = 31.5 bits (68), Expect = 2.5
 Identities = 10/15 (66%), Positives = 11/15 (73%)

Query: 186 GVCRNLPGSYVCLCP 200
           G C NLPG+Y C CP
Sbjct: 298 GTCENLPGNYTCHCP 312



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 2/35 (5%)

Query: 6   CTDVDECKSPQSCQY-GQCINTQGSYTCRCPPNYE 39
           C   D C+S Q CQ  G+CIN   SY C C   YE
Sbjct: 558 CVRKDWCES-QPCQSRGRCINLWLSYQCDCHRPYE 591


>AC092645-2|AAY14854.1|  439|Homo sapiens unknown protein.
          Length = 439

 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 52/173 (30%), Positives = 68/173 (39%), Gaps = 30/173 (17%)

Query: 5   NCTDVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTAC-YDSRKARCYGKVDLR 62
           +C  + EC S Q CQ G  C+     Y C CPP       G  C + ++ A   G V   
Sbjct: 133 HCRGISECSS-QPCQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQTAAPEGSV--- 184

Query: 63  SGTETCRDSDELSEDGTMAACCCSV-----GAAWGNYC---DPCPEPGSEAYRQL----C 110
           +G      +   ++      C C       GAA  + C   + C   G E   +L    C
Sbjct: 185 AGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHAC 244

Query: 111 PGGPGYQPVLEPPSYVVTLA------DIDECAAHEGLCAHG-TCTNTFGSFVC 156
              PG      P  Y  TLA      D+DEC   + +C  G TC NT GSF C
Sbjct: 245 VNTPGSYRCTCPGGY-RTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 31/82 (37%), Positives = 39/82 (47%), Gaps = 11/82 (13%)

Query: 131 DIDECAAH--EG---LCAHGTCTNTFGSFVCTCGAGW-SLAPXXXXXXXXXXXXRPDVCG 184
           D++EC  +  EG   LC H  C NT GS+ CTC  G+ +LA                VC 
Sbjct: 224 DVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCP 282

Query: 185 PG-VCRNLPGSYVCL---CPEG 202
            G  C N  GS+ C+   CPEG
Sbjct: 283 QGTTCINTGGSFQCVSPECPEG 304



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 1/31 (3%)

Query: 179 RPDVCGPGVCRNLPGSYVCLCPEGYVAMPNG 209
           RP +C    C N PGSY C CP GY  + +G
Sbjct: 236 RPRLC-MHACVNTPGSYRCTCPGGYRTLADG 265



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 18/35 (51%), Positives = 20/35 (57%), Gaps = 2/35 (5%)

Query: 3   GFNCTDVDECKSPQS-CQYGQ-CINTQGSYTCRCP 35
           G +C DVDEC   Q  C  G  CINT GS+ C  P
Sbjct: 265 GKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSP 299


>U57523-1|AAB06946.1|  446|Homo sapiens protein ( Human nel homolog
           mRNA, partial cds. ).
          Length = 446

 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 53/209 (25%), Positives = 71/209 (33%), Gaps = 25/209 (11%)

Query: 6   CTDVDECKSPQSCQYGQ--CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRS 63
           C D+DEC +     +    C+N  G Y C C P Y  V D +         C    +  S
Sbjct: 50  CEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFS---------CTEHDECGS 100

Query: 64  GTETCRDSDELSEDGTMAACCCSVG-AAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEP 122
           G   C ++   +      +C C  G    G  C    E G   Y   C         + P
Sbjct: 101 GQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCR-YGGTCVAP---NKCVCP 156

Query: 123 PSYVVTLA--DIDECAAHEGLC-AHGTCTNTFGSFVCTCGAG------WSLAPXXXXXXX 173
             +  +    DIDEC+     C  H  C N  G   C C +G      +SL+        
Sbjct: 157 SGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWHHCECRSGFHDDGTYSLSGESCIDID 216

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEG 202
                         C NL G + CLCP G
Sbjct: 217 ECALRTHTCWNDSACINLAGGFDCLCPCG 245



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 52/175 (29%), Positives = 72/175 (41%), Gaps = 36/175 (20%)

Query: 4   FNCTDVDECKSPQ-SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           F+CT+ DEC S Q +C +   C NT   ++C C P Y  V +GT C      R + +   
Sbjct: 90  FSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY--VGNGTIC------RAFCEEGC 141

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYC----DPCPEPGSEAY-RQLCPGGPGY 116
           R G  TC   ++         C C  G   G++C    D C E   E +    C   PG+
Sbjct: 142 RYG-GTCVAPNK---------CVCPSGFT-GSHCEKDIDECSEGIIECHNHSRCVNLPGW 190

Query: 117 ------QPVLEPPSYVV---TLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAG 161
                     +  +Y +   +  DIDECA     C +   C N  G F C C  G
Sbjct: 191 HHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPCG 245



 Score = 38.3 bits (85), Expect = 0.022
 Identities = 23/76 (30%), Positives = 28/76 (36%), Gaps = 2/76 (2%)

Query: 131 DIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPG-VC 188
           DIDECAA    C A+  C N  G + C C  G+                    C    +C
Sbjct: 52  DIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAIC 111

Query: 189 RNLPGSYVCLCPEGYV 204
            N    + C C  GYV
Sbjct: 112 TNTVQGHSCTCKPGYV 127



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 1   MPGFNCTDVDECK-SPQSC-QYGQCINTQGSYTCRCP 35
           + G +C D+DEC     +C     CIN  G + C CP
Sbjct: 207 LSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCP 243


>BC106950-1|AAI06951.1|  685|Homo sapiens delta-like 4 (Drosophila)
           protein.
          Length = 685

 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 46/205 (22%), Positives = 75/205 (36%), Gaps = 12/205 (5%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  ++ EC S      G C + +  Y C CPP Y  +    +      + C+     
Sbjct: 318 GVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSC 377

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
           R   +    + E   + T + C   V     N C    +  +    ++C   PG+     
Sbjct: 378 RERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGF----- 432

Query: 122 PPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
             +       + +CA +   CAH GTC +     +CTC AG+S                P
Sbjct: 433 --TGTYCELHVSDCARNP--CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP 488

Query: 181 DVCGPGVCRNL-PGSYVCLCPEGYV 204
                    +L   ++VC CP G+V
Sbjct: 489 CFNRATCYTDLSTDTFVCNCPYGFV 513



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 57/210 (27%), Positives = 83/210 (39%), Gaps = 37/210 (17%)

Query: 8   DVDECKSPQSCQYGQ-CINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C     C+ G  C N+ Q SYTC C P Y     G  C +   + C      R+G 
Sbjct: 284 DLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGY----TGVDC-ELELSECDSN-PCRNG- 336

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGSEAYRQLCPGGPGY 116
            +C+D     EDG    C C  G  +G +C+         PC   GS   R     G  Y
Sbjct: 337 GSCKD----QEDG--YHCLCPPG-YYGLHCEHSTLSCADSPCFNGGSCRERN---QGANY 386

Query: 117 QPVLEPPSYVVTLAD--IDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP++  +  +  +D C ++   CA+ G C N   S +C C  G++          
Sbjct: 387 ACEC-PPNFTGSNCEKKVDRCTSNP--CANGGQCLNRGPSRMCRCRPGFT---GTYCELH 440

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                R      G C +L    +C CP G+
Sbjct: 441 VSDCARNPCAHGGTCHDLENGLMCTCPAGF 470



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 6/78 (7%)

Query: 131 DIDECAAHEGLCAHG-TCTNTFG-SFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVC 188
           D++ C  H   C +G TC+N+   S+ CTC  G++                P   G G C
Sbjct: 284 DLNYCT-HHSPCKNGATCSNSGQRSYTCTCRPGYT--GVDCELELSECDSNPCRNG-GSC 339

Query: 189 RNLPGSYVCLCPEGYVAM 206
           ++    Y CLCP GY  +
Sbjct: 340 KDQEDGYHCLCPPGYYGL 357


>AY358894-1|AAQ89253.1|  685|Homo sapiens DLL4 protein.
          Length = 685

 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 46/205 (22%), Positives = 75/205 (36%), Gaps = 12/205 (5%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  ++ EC S      G C + +  Y C CPP Y  +    +      + C+     
Sbjct: 318 GVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSC 377

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
           R   +    + E   + T + C   V     N C    +  +    ++C   PG+     
Sbjct: 378 RERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGF----- 432

Query: 122 PPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
             +       + +CA +   CAH GTC +     +CTC AG+S                P
Sbjct: 433 --TGTYCELHVSDCARNP--CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP 488

Query: 181 DVCGPGVCRNL-PGSYVCLCPEGYV 204
                    +L   ++VC CP G+V
Sbjct: 489 CFNRATCYTDLSTDTFVCNCPYGFV 513



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 57/210 (27%), Positives = 83/210 (39%), Gaps = 37/210 (17%)

Query: 8   DVDECKSPQSCQYGQ-CINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C     C+ G  C N+ Q SYTC C P Y     G  C +   + C      R+G 
Sbjct: 284 DLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGY----TGVDC-ELELSECDSN-PCRNG- 336

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGSEAYRQLCPGGPGY 116
            +C+D     EDG    C C  G  +G +C+         PC   GS   R     G  Y
Sbjct: 337 GSCKD----QEDG--YHCLCPPG-YYGLHCEHSTLSCADSPCFNGGSCRERN---QGANY 386

Query: 117 QPVLEPPSYVVTLAD--IDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP++  +  +  +D C ++   CA+ G C N   S +C C  G++          
Sbjct: 387 ACEC-PPNFTGSNCEKKVDRCTSNP--CANGGQCLNRGPSRMCRCRPGFT---GTYCELH 440

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                R      G C +L    +C CP G+
Sbjct: 441 VSDCARNPCAHGGTCHDLENGLMCTCPAGF 470



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 6/78 (7%)

Query: 131 DIDECAAHEGLCAHG-TCTNTFG-SFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVC 188
           D++ C  H   C +G TC+N+   S+ CTC  G++                P   G G C
Sbjct: 284 DLNYCT-HHSPCKNGATCSNSGQRSYTCTCRPGYT--GVDCELELSECDSNPCRNG-GSC 339

Query: 189 RNLPGSYVCLCPEGYVAM 206
           ++    Y CLCP GY  +
Sbjct: 340 KDQEDGYHCLCPPGYYGL 357


>AF279305-1|AAF81912.1|  653|Homo sapiens delta 4 protein.
          Length = 653

 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 46/205 (22%), Positives = 75/205 (36%), Gaps = 12/205 (5%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  ++ EC S      G C + +  Y C CPP Y  +    +      + C+     
Sbjct: 286 GVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSC 345

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
           R   +    + E   + T + C   V     N C    +  +    ++C   PG+     
Sbjct: 346 RERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGF----- 400

Query: 122 PPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
             +       + +CA +   CAH GTC +     +CTC AG+S                P
Sbjct: 401 --TGTYCELHVSDCARNP--CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP 456

Query: 181 DVCGPGVCRNL-PGSYVCLCPEGYV 204
                    +L   ++VC CP G+V
Sbjct: 457 CFNRATCYTDLSTDTFVCNCPYGFV 481



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 57/210 (27%), Positives = 83/210 (39%), Gaps = 37/210 (17%)

Query: 8   DVDECKSPQSCQYGQ-CINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C     C+ G  C N+ Q SYTC C P Y     G  C +   + C      R+G 
Sbjct: 252 DLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGY----TGVDC-ELELSECDSN-PCRNG- 304

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGSEAYRQLCPGGPGY 116
            +C+D     EDG    C C  G  +G +C+         PC   GS   R     G  Y
Sbjct: 305 GSCKD----QEDG--YHCLCPPG-YYGLHCEHSTLSCADSPCFNGGSCRERN---QGANY 354

Query: 117 QPVLEPPSYVVTLAD--IDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP++  +  +  +D C ++   CA+ G C N   S +C C  G++          
Sbjct: 355 ACEC-PPNFTGSNCEKKVDRCTSNP--CANGGQCLNRGPSRMCRCRPGFT---GTYCELH 408

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                R      G C +L    +C CP G+
Sbjct: 409 VSDCARNPCAHGGTCHDLENGLMCTCPAGF 438



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 6/78 (7%)

Query: 131 DIDECAAHEGLCAHG-TCTNTFG-SFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVC 188
           D++ C  H   C +G TC+N+   S+ CTC  G++                P   G G C
Sbjct: 252 DLNYCT-HHSPCKNGATCSNSGQRSYTCTCRPGYT--GVDCELELSECDSNPCRNG-GSC 307

Query: 189 RNLPGSYVCLCPEGYVAM 206
           ++    Y CLCP GY  +
Sbjct: 308 KDQEDGYHCLCPPGYYGL 325


>AF253468-1|AAF76427.1|  685|Homo sapiens notch ligand DLL4 protein.
          Length = 685

 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 46/205 (22%), Positives = 75/205 (36%), Gaps = 12/205 (5%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  ++ EC S      G C + +  Y C CPP Y  +    +      + C+     
Sbjct: 318 GVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSC 377

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
           R   +    + E   + T + C   V     N C    +  +    ++C   PG+     
Sbjct: 378 RERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGF----- 432

Query: 122 PPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
             +       + +CA +   CAH GTC +     +CTC AG+S                P
Sbjct: 433 --TGTYCELHVSDCARNP--CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP 488

Query: 181 DVCGPGVCRNL-PGSYVCLCPEGYV 204
                    +L   ++VC CP G+V
Sbjct: 489 CFNRATCYTDLSTDTFVCNCPYGFV 513



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 57/210 (27%), Positives = 83/210 (39%), Gaps = 37/210 (17%)

Query: 8   DVDECKSPQSCQYGQ-CINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C     C+ G  C N+ Q SYTC C P Y     G  C +   + C      R+G 
Sbjct: 284 DLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGY----TGVDC-ELELSECDSN-PCRNG- 336

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGSEAYRQLCPGGPGY 116
            +C+D     EDG    C C  G  +G +C+         PC   GS   R     G  Y
Sbjct: 337 GSCKD----QEDG--YHCLCPPG-YYGLHCEHSTLSCADSPCFNGGSCRERN---QGANY 386

Query: 117 QPVLEPPSYVVTLAD--IDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP++  +  +  +D C ++   CA+ G C N   S +C C  G++          
Sbjct: 387 ACEC-PPNFTGSNCEKKVDRCTSNP--CANGGQCLNRGPSRMCRCRPGFT---GTYCELH 440

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                R      G C +L    +C CP G+
Sbjct: 441 VSDCARNPCAHGGTCHDLENGLMCTCPAGF 470



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 6/78 (7%)

Query: 131 DIDECAAHEGLCAHG-TCTNTFG-SFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVC 188
           D++ C  H   C +G TC+N+   S+ CTC  G++                P   G G C
Sbjct: 284 DLNYCT-HHSPCKNGATCSNSGQRSYTCTCRPGYT--GVDCELELSECDSNPCRNG-GSC 339

Query: 189 RNLPGSYVCLCPEGYVAM 206
           ++    Y CLCP GY  +
Sbjct: 340 KDQEDGYHCLCPPGYYGL 357


>AB043894-1|BAB18581.1|  685|Homo sapiens Delta-4 protein.
          Length = 685

 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 46/205 (22%), Positives = 75/205 (36%), Gaps = 12/205 (5%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  ++ EC S      G C + +  Y C CPP Y  +    +      + C+     
Sbjct: 318 GVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSC 377

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
           R   +    + E   + T + C   V     N C    +  +    ++C   PG+     
Sbjct: 378 RERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGF----- 432

Query: 122 PPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
             +       + +CA +   CAH GTC +     +CTC AG+S                P
Sbjct: 433 --TGTYCELHVSDCARNP--CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP 488

Query: 181 DVCGPGVCRNL-PGSYVCLCPEGYV 204
                    +L   ++VC CP G+V
Sbjct: 489 CFNRATCYTDLSTDTFVCNCPYGFV 513



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 57/210 (27%), Positives = 83/210 (39%), Gaps = 37/210 (17%)

Query: 8   DVDECKSPQSCQYGQ-CINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C     C+ G  C N+ Q SYTC C P Y     G  C +   + C      R+G 
Sbjct: 284 DLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGY----TGVDC-ELELSECDSN-PCRNG- 336

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGSEAYRQLCPGGPGY 116
            +C+D     EDG    C C  G  +G +C+         PC   GS   R     G  Y
Sbjct: 337 GSCKD----QEDG--YHCLCPPG-YYGLHCEHSTLSCADSPCFNGGSCRERN---QGANY 386

Query: 117 QPVLEPPSYVVTLAD--IDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP++  +  +  +D C ++   CA+ G C N   S +C C  G++          
Sbjct: 387 ACEC-PPNFTGSNCEKKVDRCTSNP--CANGGQCLNRGPSRMCRCRPGFT---GTYCELH 440

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                R      G C +L    +C CP G+
Sbjct: 441 VSDCARNPCAHGGTCHDLENGLMCTCPAGF 470



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 6/78 (7%)

Query: 131 DIDECAAHEGLCAHG-TCTNTFG-SFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVC 188
           D++ C  H   C +G TC+N+   S+ CTC  G++                P   G G C
Sbjct: 284 DLNYCT-HHSPCKNGATCSNSGQRSYTCTCRPGYT--GVDCELELSECDSNPCRNG-GSC 339

Query: 189 RNLPGSYVCLCPEGYVAM 206
           ++    Y CLCP GY  +
Sbjct: 340 KDQEDGYHCLCPPGYYGL 357


>AB036931-1|BAB16085.1|  685|Homo sapiens notch ligand delta-2
           protein.
          Length = 685

 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 46/205 (22%), Positives = 75/205 (36%), Gaps = 12/205 (5%)

Query: 3   GFNCT-DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           G +C  ++ EC S      G C + +  Y C CPP Y  +    +      + C+     
Sbjct: 318 GVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSC 377

Query: 62  RSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLE 121
           R   +    + E   + T + C   V     N C    +  +    ++C   PG+     
Sbjct: 378 RERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGF----- 432

Query: 122 PPSYVVTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
             +       + +CA +   CAH GTC +     +CTC AG+S                P
Sbjct: 433 --TGTYCELHVSDCARNP--CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP 488

Query: 181 DVCGPGVCRNL-PGSYVCLCPEGYV 204
                    +L   ++VC CP G+V
Sbjct: 489 CFNRATCYTDLSTDTFVCNCPYGFV 513



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 57/210 (27%), Positives = 83/210 (39%), Gaps = 37/210 (17%)

Query: 8   DVDECKSPQSCQYGQ-CINT-QGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           D++ C     C+ G  C N+ Q SYTC C P Y     G  C +   + C      R+G 
Sbjct: 284 DLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGY----TGVDC-ELELSECDSN-PCRNG- 336

Query: 66  ETCRDSDELSEDGTMAACCCSVGAAWGNYCD---------PCPEPGSEAYRQLCPGGPGY 116
            +C+D     EDG    C C  G  +G +C+         PC   GS   R     G  Y
Sbjct: 337 GSCKD----QEDG--YHCLCPPG-YYGLHCEHSTLSCADSPCFNGGSCRERN---QGANY 386

Query: 117 QPVLEPPSYVVTLAD--IDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXX 173
                PP++  +  +  +D C ++   CA+ G C N   S +C C  G++          
Sbjct: 387 ACEC-PPNFTGSNCEKKVDRCTSNP--CANGGQCLNRGPSRMCRCRPGFT---GTYCELH 440

Query: 174 XXXXXRPDVCGPGVCRNLPGSYVCLCPEGY 203
                R      G C +L    +C CP G+
Sbjct: 441 VSDCARNPCAHGGTCHDLENGLMCTCPAGF 470



 Score = 36.3 bits (80), Expect = 0.090
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 6/78 (7%)

Query: 131 DIDECAAHEGLCAHG-TCTNTFG-SFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVC 188
           D++ C  H   C +G TC+N+   S+ CTC  G++                P   G G C
Sbjct: 284 DLNYCT-HHSPCKNGATCSNSGQRSYTCTCRPGYT--GVDCELELSECDSNPCRNG-GSC 339

Query: 189 RNLPGSYVCLCPEGYVAM 206
           ++    Y CLCP GY  +
Sbjct: 340 KDQEDGYHCLCPPGYYGL 357


>D89629-1|BAB46925.1|  815|Homo sapiens cerebral protein-12 protein.
          Length = 815

 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 5/99 (5%)

Query: 107 RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLA 165
           R +C    G++ + E  +Y     DIDECA     C   T C NT GSF+C C  G+   
Sbjct: 418 RAVCSCRDGFRALREDNAYC---EDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRI 474

Query: 166 PXXXXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGY 203
                            C    +C N  G + C+C  GY
Sbjct: 475 DDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGY 513



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 58/218 (26%), Positives = 75/218 (34%), Gaps = 43/218 (19%)

Query: 6   CTDVDECKSPQS-CQYG-QCINTQGSYTCRCPPNYELVSDGTA-----CYDSR-----KA 53
           C D+DEC   +  C+    C+NT GS+ C C   Y  + D +      C  ++      A
Sbjct: 437 CEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENA 496

Query: 54  RCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG 113
            C+  V    G   C      + +GT     C  G   G  C         A    CP G
Sbjct: 497 LCFNTV----GGHNCVCKPGYTGNGTTCKAFCKDGCRNGGAC-------IAANVCACPQG 545

Query: 114 PGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                    PS      DIDEC+     C +   C N  G + C C  G+          
Sbjct: 546 ------FTGPS---CETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYH--DNGMFSP 594

Query: 173 XXXXXXRPDVCGPG--------VCRNLPGSYVCLCPEG 202
                   D CG G        +C NL G Y C CP G
Sbjct: 595 SGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG 632



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 50/168 (29%), Positives = 65/168 (38%), Gaps = 22/168 (13%)

Query: 4   FNCTDVDECKSPQ-SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           ++CT+ DEC + Q +C +   C NT G + C C P Y    +GT C    KA C  K   
Sbjct: 477 YSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGY--TGNGTTC----KAFC--KDGC 528

Query: 62  RSGTETCRDSDELSEDGTMAACC------CSVGAAWGNYCDPCPE-PGSEAYRQLCPGGP 114
           R+G      +      G     C      CS G    +    C   PG   Y   C  G 
Sbjct: 529 RNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPG--WYHCECRDGY 586

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAG 161
               +  P     +  DIDEC      CA+ T C N  G + C C  G
Sbjct: 587 HDNGMFSPSG--ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG 632



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 5/59 (8%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           G +C D+DEC + + SC     C N  G Y CRCP       D   C    K +  G++
Sbjct: 596 GESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD---CIHDGKVKHNGQI 651



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 48/208 (23%), Positives = 72/208 (34%), Gaps = 35/208 (16%)

Query: 11  ECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRD 70
           ECK     Q  + + + G     CP ++++    + C       C G  D  S    C +
Sbjct: 359 ECKD----QTMKLVESSGCPALDCPESHQITLSHSCC-----KVCKG-YDFCSERHNCME 408

Query: 71  SDELSEDGTMAACCCSVGAAW----GNYC---DPCPEPGSEAYRQ--LCPGGPGYQPVLE 121
           +         A C C  G         YC   D C E G    R+  +C   PG    + 
Sbjct: 409 NSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAE-GRHYCRENTMCVNTPGSFMCIC 467

Query: 122 PPSYV----VTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
              Y+     +  + DEC  ++  C  +  C NT G   C C  G++             
Sbjct: 468 KTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYT------GNGTTCK 521

Query: 177 XXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
               D C   G C     + VC CP+G+
Sbjct: 522 AFCKDGCRNGGAC---IAANVCACPQGF 546



 Score = 31.9 bits (69), Expect = 1.9
 Identities = 19/81 (23%), Positives = 30/81 (37%), Gaps = 3/81 (3%)

Query: 133 DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD--VCGPG-VCR 189
           D C+       +  C N     VC+C  G+                      C    +C 
Sbjct: 398 DFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCV 457

Query: 190 NLPGSYVCLCPEGYVAMPNGS 210
           N PGS++C+C  GY+ + + S
Sbjct: 458 NTPGSFMCICKTGYIRIDDYS 478



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 3/39 (7%)

Query: 3   GFNC-TDVDECKSP--QSCQYGQCINTQGSYTCRCPPNY 38
           G +C TD+DEC     Q      CIN  G Y C C   Y
Sbjct: 548 GPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGY 586


>D83018-1|BAA11681.1|  816|Homo sapiens nel-related protein 2
           protein.
          Length = 816

 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 5/99 (5%)

Query: 107 RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLA 165
           R +C    G++ + E  +Y     DIDECA     C   T C NT GSF+C C  G+   
Sbjct: 419 RAVCSCRDGFRALREDNAYC---EDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRI 475

Query: 166 PXXXXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGY 203
                            C    +C N  G + C+C  GY
Sbjct: 476 DDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGY 514



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 58/218 (26%), Positives = 75/218 (34%), Gaps = 43/218 (19%)

Query: 6   CTDVDECKSPQS-CQYG-QCINTQGSYTCRCPPNYELVSDGTA-----CYDSR-----KA 53
           C D+DEC   +  C+    C+NT GS+ C C   Y  + D +      C  ++      A
Sbjct: 438 CEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENA 497

Query: 54  RCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG 113
            C+  V    G   C      + +GT     C  G   G  C         A    CP G
Sbjct: 498 LCFNTV----GGHNCVCKPGYTGNGTTCKAFCKDGCRNGGAC-------IAANVCACPQG 546

Query: 114 PGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                    PS      DIDEC+     C +   C N  G + C C  G+          
Sbjct: 547 ------FTGPS---CETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYH--DNGMFSP 595

Query: 173 XXXXXXRPDVCGPG--------VCRNLPGSYVCLCPEG 202
                   D CG G        +C NL G Y C CP G
Sbjct: 596 SGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG 633



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 50/168 (29%), Positives = 65/168 (38%), Gaps = 22/168 (13%)

Query: 4   FNCTDVDECKSPQ-SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           ++CT+ DEC + Q +C +   C NT G + C C P Y    +GT C    KA C  K   
Sbjct: 478 YSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGY--TGNGTTC----KAFC--KDGC 529

Query: 62  RSGTETCRDSDELSEDGTMAACC------CSVGAAWGNYCDPCPE-PGSEAYRQLCPGGP 114
           R+G      +      G     C      CS G    +    C   PG   Y   C  G 
Sbjct: 530 RNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPG--WYHCECRDGY 587

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAG 161
               +  P     +  DIDEC      CA+ T C N  G + C C  G
Sbjct: 588 HDNGMFSPSG--ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG 633



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 5/59 (8%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           G +C D+DEC + + SC     C N  G Y CRCP       D   C    K +  G++
Sbjct: 597 GESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD---CIHDGKVKHNGQI 652



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 48/208 (23%), Positives = 72/208 (34%), Gaps = 35/208 (16%)

Query: 11  ECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRD 70
           ECK     Q  + + + G     CP ++++    + C       C G  D  S    C +
Sbjct: 360 ECKD----QTMKLVESSGCPALDCPESHQITLSHSCC-----KVCKG-YDFCSERHNCME 409

Query: 71  SDELSEDGTMAACCCSVGAAW----GNYC---DPCPEPGSEAYRQ--LCPGGPGYQPVLE 121
           +         A C C  G         YC   D C E G    R+  +C   PG    + 
Sbjct: 410 NSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAE-GRHYCRENTMCVNTPGSFMCIC 468

Query: 122 PPSYV----VTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
              Y+     +  + DEC  ++  C  +  C NT G   C C  G++             
Sbjct: 469 KTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYT------GNGTTCK 522

Query: 177 XXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
               D C   G C     + VC CP+G+
Sbjct: 523 AFCKDGCRNGGAC---IAANVCACPQGF 547



 Score = 31.9 bits (69), Expect = 1.9
 Identities = 19/81 (23%), Positives = 30/81 (37%), Gaps = 3/81 (3%)

Query: 133 DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD--VCGPG-VCR 189
           D C+       +  C N     VC+C  G+                      C    +C 
Sbjct: 399 DFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCV 458

Query: 190 NLPGSYVCLCPEGYVAMPNGS 210
           N PGS++C+C  GY+ + + S
Sbjct: 459 NTPGSFMCICKTGYIRIDDYS 479



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 3/39 (7%)

Query: 3   GFNC-TDVDECKSP--QSCQYGQCINTQGSYTCRCPPNY 38
           G +C TD+DEC     Q      CIN  G Y C C   Y
Sbjct: 549 GPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGY 587


>BC020544-1|AAH20544.1|  816|Homo sapiens NELL2 protein protein.
          Length = 816

 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 5/99 (5%)

Query: 107 RQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAGWSLA 165
           R +C    G++ + E  +Y     DIDECA     C   T C NT GSF+C C  G+   
Sbjct: 419 RAVCSCRDGFRALREDNAYC---EDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRI 475

Query: 166 PXXXXXXXXXXXXRPDVCGP-GVCRNLPGSYVCLCPEGY 203
                            C    +C N  G + C+C  GY
Sbjct: 476 DDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGY 514



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 58/218 (26%), Positives = 75/218 (34%), Gaps = 43/218 (19%)

Query: 6   CTDVDECKSPQS-CQYG-QCINTQGSYTCRCPPNYELVSDGTA-----CYDSR-----KA 53
           C D+DEC   +  C+    C+NT GS+ C C   Y  + D +      C  ++      A
Sbjct: 438 CEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENA 497

Query: 54  RCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGG 113
            C+  V    G   C      + +GT     C  G   G  C         A    CP G
Sbjct: 498 LCFNTV----GGHNCVCKPGYTGNGTTCKAFCKDGCRNGGAC-------IAANVCACPQG 546

Query: 114 PGYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXX 172
                    PS      DIDEC+     C +   C N  G + C C  G+          
Sbjct: 547 ------FTGPS---CETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYH--DNGMFSP 595

Query: 173 XXXXXXRPDVCGPG--------VCRNLPGSYVCLCPEG 202
                   D CG G        +C NL G Y C CP G
Sbjct: 596 SGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG 633



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 50/168 (29%), Positives = 65/168 (38%), Gaps = 22/168 (13%)

Query: 4   FNCTDVDECKSPQ-SC-QYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDL 61
           ++CT+ DEC + Q +C +   C NT G + C C P Y    +GT C    KA C  K   
Sbjct: 478 YSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGY--TGNGTTC----KAFC--KDGC 529

Query: 62  RSGTETCRDSDELSEDGTMAACC------CSVGAAWGNYCDPCPE-PGSEAYRQLCPGGP 114
           R+G      +      G     C      CS G    +    C   PG   Y   C  G 
Sbjct: 530 RNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPG--WYHCECRDGY 587

Query: 115 GYQPVLEPPSYVVTLADIDECAAHEGLCAHGT-CTNTFGSFVCTCGAG 161
               +  P     +  DIDEC      CA+ T C N  G + C C  G
Sbjct: 588 HDNGMFSPSG--ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG 633



 Score = 37.9 bits (84), Expect = 0.029
 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 5/59 (8%)

Query: 3   GFNCTDVDECKSPQ-SCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKV 59
           G +C D+DEC + + SC     C N  G Y CRCP       D   C    K +  G++
Sbjct: 597 GESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD---CIHDGKVKHNGQI 652



 Score = 33.9 bits (74), Expect = 0.48
 Identities = 48/208 (23%), Positives = 72/208 (34%), Gaps = 35/208 (16%)

Query: 11  ECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTETCRD 70
           ECK     Q  + + + G     CP ++++    + C       C G  D  S    C +
Sbjct: 360 ECKD----QTMKLVESSGCPALDCPESHQITLSHSCC-----KVCKG-YDFCSERHNCME 409

Query: 71  SDELSEDGTMAACCCSVGAAW----GNYC---DPCPEPGSEAYRQ--LCPGGPGYQPVLE 121
           +         A C C  G         YC   D C E G    R+  +C   PG    + 
Sbjct: 410 NSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAE-GRHYCRENTMCVNTPGSFMCIC 468

Query: 122 PPSYV----VTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXX 176
              Y+     +  + DEC  ++  C  +  C NT G   C C  G++             
Sbjct: 469 KTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYT------GNGTTCK 522

Query: 177 XXRPDVC-GPGVCRNLPGSYVCLCPEGY 203
               D C   G C     + VC CP+G+
Sbjct: 523 AFCKDGCRNGGAC---IAANVCACPQGF 547



 Score = 31.9 bits (69), Expect = 1.9
 Identities = 19/81 (23%), Positives = 30/81 (37%), Gaps = 3/81 (3%)

Query: 133 DECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPD--VCGPG-VCR 189
           D C+       +  C N     VC+C  G+                      C    +C 
Sbjct: 399 DFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCV 458

Query: 190 NLPGSYVCLCPEGYVAMPNGS 210
           N PGS++C+C  GY+ + + S
Sbjct: 459 NTPGSFMCICKTGYIRIDDYS 479



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 3/39 (7%)

Query: 3   GFNC-TDVDECKSP--QSCQYGQCINTQGSYTCRCPPNY 38
           G +C TD+DEC     Q      CIN  G Y C C   Y
Sbjct: 549 GPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGY 587


>AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.
          Length = 1200

 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 53/200 (26%), Positives = 71/200 (35%), Gaps = 27/200 (13%)

Query: 10  DECKSPQSCQYGQCINTQGSYTCRCPPNYE-LVSDGTACYDSRKARCY-GKVDLRSGTE- 66
           DEC     C +G C+     + C C  N+  L+ D    Y      C  G   + +  + 
Sbjct: 274 DECVPYPGCVHGSCVEP---WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQ 330

Query: 67  ---TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPP 123
              TC D             C S   A G  C   P  G E +   CP G         P
Sbjct: 331 YRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPS-GFECH---CPSG------WSGP 380

Query: 124 SYVVTLADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC 183
           +  +   DIDECA++    A GTC +    F C C   W  A             R    
Sbjct: 381 TCAL---DIDECASNP-CAAGGTCVDQVDGFECICPEQWVGA----TCQLDVNDCRGQCQ 432

Query: 184 GPGVCRNLPGSYVCLCPEGY 203
             G C++L   Y C+CP G+
Sbjct: 433 HGGTCKDLVNGYQCVCPRGF 452



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 49/199 (24%), Positives = 72/199 (36%), Gaps = 33/199 (16%)

Query: 8   DVDECKSPQSCQYG-QCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTE 66
           DVD C+ P  C+ G +C N +G Y C CP ++     G  C   R+  C G         
Sbjct: 498 DVDLCE-PSPCRNGARCYNLEGDYYCACPDDF----GGKNCSVPREP-CPG--------G 543

Query: 67  TCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVLEPPSYV 126
            CR  D    D        +     G +     +PG   +  +C  G          +  
Sbjct: 544 ACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGN-FSCICDSG---------FTGT 593

Query: 127 VTLADIDECAAHEGLCAH-GTCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVC-G 184
               +ID+C      C + GTC +   +F C C +GW                 PD C  
Sbjct: 594 YCHENIDDCLGQP--CRNGGTCIDEVDAFRCFCPSGWE----GELCDTNPNDCLPDPCHS 647

Query: 185 PGVCRNLPGSYVCLCPEGY 203
            G C +L   + C C +G+
Sbjct: 648 RGRCYDLVNDFYCACDDGW 666



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 38/124 (30%), Positives = 49/124 (39%), Gaps = 25/124 (20%)

Query: 2   PGF---NCT-DVDECKSPQSCQYGQ-CINTQGSYTCRCPPN------YELVSDGTACYDS 50
           PGF   +C  ++DEC+S   C YG  C++    Y C CPP        E++  G +C+  
Sbjct: 779 PGFAGPDCRINIDECQS-SPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSR 837

Query: 51  RKARCYGKVDLRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGS-EAYRQL 109
                +G     S  E C     L  DG     C  V   W     PC   G  EA    
Sbjct: 838 GTPFPHGS----SWVEDCNSCRCL--DGRRD--CSKVWCGW----KPCLLAGQPEALSAQ 885

Query: 110 CPGG 113
           CP G
Sbjct: 886 CPLG 889



 Score = 34.7 bits (76), Expect = 0.27
 Identities = 62/229 (27%), Positives = 79/229 (34%), Gaps = 40/229 (17%)

Query: 8   DVDECKSPQSCQYG-QCINTQ-GSYTCRCPPNYE---LVSDGTACYDSRKARCYGKVDLR 62
           D++ C S   C  G  CIN +   Y C CP  Y          AC  +  A      ++ 
Sbjct: 307 DLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVP 366

Query: 63  SGTE----------TCR-DSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQL-- 109
           SG E          TC  D DE + +   A   C V    G  C  CPE    A  QL  
Sbjct: 367 SGFECHCPSGWSGPTCALDIDECASNPCAAGGTC-VDQVDGFECI-CPEQWVGATCQLDV 424

Query: 110 ------CPGGP-------GYQPVLEPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFV 155
                 C  G        GYQ V  P  +     +++        C + G C +    F 
Sbjct: 425 NDCRGQCQHGGTCKDLVNGYQCVC-PRGFGGRHCELERDKCASSPCHSGGLCEDLADGFH 483

Query: 156 CTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
           C C  G+S  P             P  C  G  C NL G Y C CP+ +
Sbjct: 484 CHCPQGFS-GPLCEVDVDLC---EPSPCRNGARCYNLEGDYYCACPDDF 528



 Score = 34.3 bits (75), Expect = 0.36
 Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 4/84 (4%)

Query: 122 PPSYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRP 180
           P  Y     +  E A     CA+G +C      F C C +GWS  P             P
Sbjct: 336 PDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS-GPTCALDIDECAS-NP 393

Query: 181 DVCGPGVCRNLPGSYVCLCPEGYV 204
              G G C +    + C+CPE +V
Sbjct: 394 CAAG-GTCVDQVDGFECICPEQWV 416



 Score = 33.5 bits (73), Expect = 0.63
 Identities = 38/160 (23%), Positives = 58/160 (36%), Gaps = 19/160 (11%)

Query: 8   DVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGTET 67
           ++D+C        G CI+   ++ C CP  +E     T   D     C+ +       + 
Sbjct: 598 NIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCY---DL 654

Query: 68  CRDSDELSEDGTMAACCCSVGAAWGNY-CD---PCPEPGSEAYRQLCPGGPGYQPVLEPP 123
             D     +DG     C S       Y C     C + G + +R  CP  PG++      
Sbjct: 655 VNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSG-DTFRCACP--PGWK------ 705

Query: 124 SYVVTLADIDECAAHEGLCAHG-TCTNTFGSFVCTCGAGW 162
                +A    C  +   C +G TC  +  SF C C  GW
Sbjct: 706 GSTCAVAKNSSCLPNP--CVNGGTCVGSGASFSCICRDGW 743



 Score = 33.1 bits (72), Expect = 0.83
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 5/71 (7%)

Query: 134 ECAAHEGLCAHG-TCTNTFGSFVCTCGAGWSLAPXXXXXXXXXXXXRPDVCGPGVCRNLP 192
           +C A+   C++G TC ++  +F C C  GW                 P V G G C    
Sbjct: 677 QCDAYT--CSNGGTCYDSGDTFRCACPPGWK-GSTCAVAKNSSCLPNPCVNG-GTCVGSG 732

Query: 193 GSYVCLCPEGY 203
            S+ C+C +G+
Sbjct: 733 ASFSCICRDGW 743


>D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein.
          Length = 1376

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/45 (46%), Positives = 24/45 (53%), Gaps = 2/45 (4%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G  CTDVDEC   +      C NT GS++CRC P Y    DG  C
Sbjct: 888 GHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGY--YGDGFQC 930



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 46/163 (28%), Positives = 56/163 (34%), Gaps = 39/163 (23%)

Query: 3   GFNCTDVDECKSP-QSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G NC D +EC +    C     CIN  GSY C C   YE   D   C           + 
Sbjct: 797 GRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTC-----------IL 845

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
           +      C D          A C    G+ +   C P        Y      G G+Q   
Sbjct: 846 ITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLP-------GY-----AGDGHQ--- 890

Query: 121 EPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGW 162
                     D+DEC+  E  C    TC NT GSF C C  G+
Sbjct: 891 --------CTDVDECS--ENRCHPAATCYNTPGSFSCRCQPGY 923



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 15/22 (68%), Positives = 15/22 (68%), Gaps = 1/22 (4%)

Query: 183 CGPG-VCRNLPGSYVCLCPEGY 203
           CGP  VC NLPGSY C C  GY
Sbjct: 813 CGPNSVCINLPGSYRCECRSGY 834



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 30/108 (27%), Positives = 40/108 (37%), Gaps = 12/108 (11%)

Query: 101 PGSEAYRQLCPGGPGYQPVLEPPSYVVTLADIDECAAHEGLCA---HGTCTNTFGS-FVC 156
           PGS  YR  C    GY+   +  + ++     + C      CA      C +  GS F C
Sbjct: 823 PGS--YR--CECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSC 878

Query: 157 TCGAGWSLAPXXXXXXXXXXXXRPDVCGPGV-CRNLPGSYVCLCPEGY 203
            C  G++               R   C P   C N PGS+ C C  GY
Sbjct: 879 ACLPGYAGDGHQCTDVDECSENR---CHPAATCYNTPGSFSCRCQPGY 923


>BC113577-1|AAI13578.1| 1015|Homo sapiens tolloid-like 2 protein.
          Length = 1015

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 7/62 (11%)

Query: 8   DVDECKSPQ--SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           +VDEC  P    C++ +C+NT GSY C C P YEL +D   C    +  C G +   +GT
Sbjct: 576 EVDECSWPDHGGCEH-RCVNTLGSYKCACDPGYELAADKKMC----EVACGGFITKLNGT 630

Query: 66  ET 67
            T
Sbjct: 631 IT 632



 Score = 46.4 bits (105), Expect = 8e-05
 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 5/60 (8%)

Query: 7   TDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           +D DEC K    CQ+ +C+NT GSY CRC   Y L  +G   +D ++A C  K+    GT
Sbjct: 731 SDKDECAKDNGGCQH-ECVNTFGSYLCRCRNGYWLHENG---HDCKEAGCAHKISSVEGT 786



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 1/35 (2%)

Query: 130 ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
           +D DECA   G C H  C NTFGS++C C  G+ L
Sbjct: 731 SDKDECAKDNGGCQH-ECVNTFGSYLCRCRNGYWL 764



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 2/36 (5%)

Query: 131 DIDECA-AHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
           ++DEC+    G C H  C NT GS+ C C  G+ LA
Sbjct: 576 EVDECSWPDHGGCEH-RCVNTLGSYKCACDPGYELA 610


>BC112366-1|AAI12367.1| 1015|Homo sapiens tolloid-like 2 protein.
          Length = 1015

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 7/62 (11%)

Query: 8   DVDECKSPQ--SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           +VDEC  P    C++ +C+NT GSY C C P YEL +D   C    +  C G +   +GT
Sbjct: 576 EVDECSWPDHGGCEH-RCVNTLGSYKCACDPGYELAADKKMC----EVACGGFITKLNGT 630

Query: 66  ET 67
            T
Sbjct: 631 IT 632



 Score = 46.4 bits (105), Expect = 8e-05
 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 5/60 (8%)

Query: 7   TDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           +D DEC K    CQ+ +C+NT GSY CRC   Y L  +G   +D ++A C  K+    GT
Sbjct: 731 SDKDECAKDNGGCQH-ECVNTFGSYLCRCRNGYWLHENG---HDCKEAGCAHKISSVEGT 786



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 1/35 (2%)

Query: 130 ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
           +D DECA   G C H  C NTFGS++C C  G+ L
Sbjct: 731 SDKDECAKDNGGCQH-ECVNTFGSYLCRCRNGYWL 764



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 2/36 (5%)

Query: 131 DIDECA-AHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
           ++DEC+    G C H  C NT GS+ C C  G+ LA
Sbjct: 576 EVDECSWPDHGGCEH-RCVNTLGSYKCACDPGYELA 610


>BC112341-1|AAI12342.1| 1015|Homo sapiens tolloid-like 2 protein.
          Length = 1015

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 7/62 (11%)

Query: 8   DVDECKSPQ--SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           +VDEC  P    C++ +C+NT GSY C C P YEL +D   C    +  C G +   +GT
Sbjct: 576 EVDECSWPDHGGCEH-RCVNTLGSYKCACDPGYELAADKKMC----EVACGGFITKLNGT 630

Query: 66  ET 67
            T
Sbjct: 631 IT 632



 Score = 46.4 bits (105), Expect = 8e-05
 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 5/60 (8%)

Query: 7   TDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           +D DEC K    CQ+ +C+NT GSY CRC   Y L  +G   +D ++A C  K+    GT
Sbjct: 731 SDKDECAKDNGGCQH-ECVNTFGSYLCRCRNGYWLHENG---HDCKEAGCAHKISSVEGT 786



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 1/35 (2%)

Query: 130 ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
           +D DECA   G C H  C NTFGS++C C  G+ L
Sbjct: 731 SDKDECAKDNGGCQH-ECVNTFGSYLCRCRNGYWL 764



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 2/36 (5%)

Query: 131 DIDECA-AHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
           ++DEC+    G C H  C NT GS+ C C  G+ LA
Sbjct: 576 EVDECSWPDHGGCEH-RCVNTLGSYKCACDPGYELA 610


>BC035608-1|AAH35608.1|  969|Homo sapiens NID2 protein protein.
          Length = 969

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/45 (46%), Positives = 24/45 (53%), Gaps = 2/45 (4%)

Query: 3   GFNCTDVDECKSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTAC 47
           G  CTDVDEC   +      C NT GS++CRC P Y    DG  C
Sbjct: 481 GHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGY--YGDGFQC 523



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 46/163 (28%), Positives = 56/163 (34%), Gaps = 39/163 (23%)

Query: 3   GFNCTDVDECKSP-QSCQYGQ-CINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVD 60
           G NC D +EC +    C     CIN  GSY C C   YE   D   C           + 
Sbjct: 390 GRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSAYEFADDRHTC-----------IL 438

Query: 61  LRSGTETCRDSDELSEDGTMAACCCSVGAAWGNYCDPCPEPGSEAYRQLCPGGPGYQPVL 120
           +      C D          A C    G+ +   C P        Y      G G+Q   
Sbjct: 439 ITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLP-------GY-----AGDGHQ--- 483

Query: 121 EPPSYVVTLADIDECAAHEGLC-AHGTCTNTFGSFVCTCGAGW 162
                     D+DEC+  E  C    TC NT GSF C C  G+
Sbjct: 484 --------CTDVDECS--ENRCHPAATCYNTPGSFSCRCQPGY 516



 Score = 33.1 bits (72), Expect = 0.83
 Identities = 14/22 (63%), Positives = 14/22 (63%), Gaps = 1/22 (4%)

Query: 183 CGPG-VCRNLPGSYVCLCPEGY 203
           CGP  VC NLPGSY C C   Y
Sbjct: 406 CGPNSVCINLPGSYRCECRSAY 427


>AL391136-1|CAH72234.1| 1015|Homo sapiens tolloid-like 2 protein.
          Length = 1015

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 7/62 (11%)

Query: 8   DVDECKSPQ--SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           +VDEC  P    C++ +C+NT GSY C C P YEL +D   C    +  C G +   +GT
Sbjct: 576 EVDECSWPDHGGCEH-RCVNTLGSYKCACDPGYELAADKKMC----EVACGGFITKLNGT 630

Query: 66  ET 67
            T
Sbjct: 631 IT 632



 Score = 46.4 bits (105), Expect = 8e-05
 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 5/60 (8%)

Query: 7   TDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           +D DEC K    CQ+ +C+NT GSY CRC   Y L  +G   +D ++A C  K+    GT
Sbjct: 731 SDKDECAKDNGGCQH-ECVNTFGSYLCRCRNGYWLHENG---HDCKEAGCAHKISSVEGT 786



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 1/35 (2%)

Query: 130 ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
           +D DECA   G C H  C NTFGS++C C  G+ L
Sbjct: 731 SDKDECAKDNGGCQH-ECVNTFGSYLCRCRNGYWL 764



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 2/36 (5%)

Query: 131 DIDECA-AHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
           ++DEC+    G C H  C NT GS+ C C  G+ LA
Sbjct: 576 EVDECSWPDHGGCEH-RCVNTLGSYKCACDPGYELA 610


>AL138765-2|CAI13580.1| 1015|Homo sapiens tolloid-like 2 protein.
          Length = 1015

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 7/62 (11%)

Query: 8   DVDECKSPQ--SCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           +VDEC  P    C++ +C+NT GSY C C P YEL +D   C    +  C G +   +GT
Sbjct: 576 EVDECSWPDHGGCEH-RCVNTLGSYKCACDPGYELAADKKMC----EVACGGFITKLNGT 630

Query: 66  ET 67
            T
Sbjct: 631 IT 632



 Score = 46.4 bits (105), Expect = 8e-05
 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 5/60 (8%)

Query: 7   TDVDEC-KSPQSCQYGQCINTQGSYTCRCPPNYELVSDGTACYDSRKARCYGKVDLRSGT 65
           +D DEC K    CQ+ +C+NT GSY CRC   Y L  +G   +D ++A C  K+    GT
Sbjct: 731 SDKDECAKDNGGCQH-ECVNTFGSYLCRCRNGYWLHENG---HDCKEAGCAHKISSVEGT 786



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 1/35 (2%)

Query: 130 ADIDECAAHEGLCAHGTCTNTFGSFVCTCGAGWSL 164
           +D DECA   G C H  C NTFGS++C C  G+ L
Sbjct: 731 SDKDECAKDNGGCQH-ECVNTFGSYLCRCRNGYWL 764



 Score = 37.1 bits (82), Expect = 0.051
 Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 2/36 (5%)

Query: 131 DIDECA-AHEGLCAHGTCTNTFGSFVCTCGAGWSLA 165
           ++DEC+    G C H  C NT GS+ C C  G+ LA
Sbjct: 576 EVDECSWPDHGGCEH-RCVNTLGSYKCACDPGYELA 610


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.321    0.138    0.480 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 42,807,118
Number of Sequences: 224733
Number of extensions: 2124984
Number of successful extensions: 15567
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 544
Number of HSP's successfully gapped in prelim test: 248
Number of HSP's that attempted gapping in prelim test: 4746
Number of HSP's gapped (non-prelim): 5955
length of query: 229
length of database: 73,234,838
effective HSP length: 87
effective length of query: 142
effective length of database: 53,683,067
effective search space: 7622995514
effective search space used: 7622995514
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 64 (29.9 bits)