Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000207-TA|BGIBMGA000207-PA|IPR002212|Matrix
fibril-associated, IPR006209|EGF-like, IPR013091|EGF calcium-binding,
IPR009030|Growth factor, receptor, IPR000152|Aspartic acid and
asparagine hydroxylation site, IPR013032|EGF-like region,
IPR000742|EGF-like, type 3, IPR001881|EGF-like calcium-binding,
IPR006210|EGF
(568 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital... 457 e-128
X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein. 454 e-127
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 454 e-127
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein. 437 e-122
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ... 436 e-122
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ... 436 e-122
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ... 436 e-122
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein. 436 e-122
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein. 436 e-122
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein. 436 e-122
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. 433 e-121
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. 429 e-119
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. 429 e-119
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. 429 e-119
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 344 4e-94
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 344 4e-94
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 341 4e-93
M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein. 334 5e-91
BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro... 334 5e-91
AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac... 334 5e-91
AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro... 334 5e-91
AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein. 332 2e-90
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein. 331 3e-90
Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein. 299 2e-80
S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt... 299 2e-80
BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming gro... 299 2e-80
AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming gro... 299 2e-80
X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein. 279 3e-74
AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant pro... 252 2e-66
BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein. 237 8e-62
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein. 237 8e-62
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro... 237 8e-62
AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens ... 236 2e-61
X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein. 231 5e-60
BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein. 231 5e-60
U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor prot... 227 1e-58
BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein. 225 2e-58
BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein. 225 2e-58
AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein pr... 225 2e-58
BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein. 225 4e-58
AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein. 225 4e-58
Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein. 224 6e-58
Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein. 224 6e-58
AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein. 224 6e-58
AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens ... 224 6e-58
AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein. 223 2e-57
X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein. 222 2e-57
X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein. 222 3e-57
X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein. 222 3e-57
U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein. 222 3e-57
AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D pre... 222 3e-57
AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein. 218 4e-56
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 202 3e-51
Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA seque... 197 1e-49
Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA seque... 197 1e-49
AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein. 197 1e-49
AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens ... 196 2e-49
AF525689-1|AAN77133.1| 988|Homo sapiens signal peptide-CUB-EGF-... 195 3e-49
Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA seque... 194 7e-49
BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein. 194 7e-49
BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB dom... 194 7e-49
AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and... 194 7e-49
AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens ... 194 7e-49
AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein. 194 7e-49
AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing ... 194 7e-49
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 192 3e-48
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 192 3e-48
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 192 3e-48
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 192 3e-48
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 192 3e-48
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 192 3e-48
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 192 3e-48
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 192 3e-48
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 192 3e-48
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 192 4e-48
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 191 7e-48
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 191 7e-48
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 191 7e-48
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 191 7e-48
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 191 7e-48
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 190 9e-48
AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens ... 190 9e-48
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 190 9e-48
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 174 6e-43
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 174 6e-43
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 174 6e-43
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant... 174 6e-43
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. 171 6e-42
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 171 6e-42
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 171 6e-42
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 171 6e-42
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 171 6e-42
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 171 6e-42
CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein. 161 5e-39
BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing fibulin-... 161 5e-39
AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein. 161 5e-39
AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein. 161 5e-39
AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing fibulin-... 161 5e-39
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 161 5e-39
AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding prot... 161 5e-39
BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein. 161 8e-39
AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellu... 161 8e-39
AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming gro... 159 2e-38
BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 158 6e-38
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 155 4e-37
D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 155 4e-37
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 155 4e-37
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 155 4e-37
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 155 4e-37
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 155 4e-37
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 155 4e-37
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 155 5e-37
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 155 5e-37
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 155 5e-37
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 155 5e-37
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 155 5e-37
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 155 5e-37
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 155 5e-37
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 155 5e-37
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 154 7e-37
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 154 9e-37
AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein. 152 3e-36
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 151 5e-36
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 151 5e-36
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 150 1e-35
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 150 1e-35
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 150 1e-35
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 150 1e-35
DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module contain... 150 1e-35
BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein. 150 1e-35
AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane hel... 150 1e-35
X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein. 149 2e-35
CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein. 148 6e-35
BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein. 148 6e-35
AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein. 148 6e-35
AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries ... 148 6e-35
AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein. 146 2e-34
AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein pr... 146 2e-34
U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein pro... 146 2e-34
BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing fibulin-... 146 2e-34
BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing fibulin-... 146 2e-34
AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing fibulin-... 146 2e-34
AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module contain... 146 2e-34
AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2 pr... 146 2e-34
AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing fibulin-... 146 2e-34
AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane hel... 146 2e-34
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. 144 1e-33
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. 144 1e-33
AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein. 144 1e-33
X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane ... 143 1e-33
AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane hel... 143 1e-33
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. 142 2e-33
BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module contain... 142 3e-33
BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module contain... 142 3e-33
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. 142 3e-33
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. 142 3e-33
AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. 142 3e-33
U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein. 142 4e-33
BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein. 140 2e-32
AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein. 138 5e-32
AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens ... 137 8e-32
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. 134 8e-31
AK027775-1|BAB55358.1| 537|Homo sapiens protein ( Homo sapiens ... 134 1e-30
AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein. 133 1e-30
AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA seq... 129 2e-29
AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein pr... 126 2e-28
U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein. 126 2e-28
BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein. 126 2e-28
AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1,... 126 2e-28
AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1,... 126 2e-28
AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS... 124 8e-28
AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein. 123 2e-27
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p... 122 3e-27
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 122 3e-27
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 122 3e-27
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 122 3e-27
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 122 3e-27
AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens ... 120 2e-26
D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein. 119 2e-26
DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein. 119 2e-26
AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein. 119 2e-26
AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein. 119 2e-26
AF054501-1|AAC39881.1| 161|Homo sapiens latent transforming gro... 118 4e-26
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. 116 2e-25
D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein. 115 4e-25
BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 115 4e-25
BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 115 4e-25
BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor p... 115 4e-25
Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein. 114 7e-25
M57853-1|AAA60357.1| 676|Homo sapiens S protein protein. 114 7e-25
M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein. 114 7e-25
M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin K... 114 7e-25
BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein. 114 7e-25
AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein. 114 7e-25
X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA ... 114 9e-25
M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein. 114 9e-25
D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein. 113 2e-24
D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2 pro... 113 2e-24
BC053933-1|AAH53933.1| 239|Homo sapiens EMR2 protein protein. 113 2e-24
BC034949-1|AAH34949.1| 239|Homo sapiens EMR2 protein protein. 113 2e-24
BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein. 113 2e-24
AK074499-1|BAC11024.1| 636|Homo sapiens protein ( Homo sapiens ... 113 2e-24
AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens ... 112 3e-24
AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein. 111 5e-24
L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific pr... 110 1e-23
BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific ... 110 1e-23
BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific ... 110 1e-23
AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specifi... 110 1e-23
AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens ... 110 1e-23
X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for ... 109 3e-23
BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor... 109 3e-23
BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor... 109 3e-23
BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multip... 109 3e-23
AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal gro... 109 3e-23
AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein. 109 3e-23
AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens ... 109 3e-23
AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein pr... 109 3e-23
AF193055-1|AAG22483.1| 474|Homo sapiens unknown protein. 109 3e-23
AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor... 109 3e-23
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs... 109 3e-23
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso... 109 3e-23
AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 109 3e-23
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 109 3e-23
AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 109 3e-23
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. 109 3e-23
AL021578-1|CAB46380.1| 622|Homo sapiens matrilin 4 protein. 108 4e-23
AL021578-2|CAI21077.1| 432|Homo sapiens matrilin 4 protein. 107 8e-23
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ... 105 4e-22
Y13341-1|CAA73785.1| 310|Homo sapiens matrilin-3 precursor prot... 105 6e-22
X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein. 105 6e-22
M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein. 105 6e-22
M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein. 105 6e-22
BC139907-1|AAI39908.1| 486|Homo sapiens matrilin 3 protein. 105 6e-22
AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein. 105 6e-22
AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein. 105 6e-22
AJ224741-1|CAA12110.1| 486|Homo sapiens matrilin-3 protein. 105 6e-22
AJ001047-1|CAA04501.1| 303|Homo sapiens Matrilin-3 protein. 105 6e-22
AC079145-2|AAX88937.1| 486|Homo sapiens unknown protein. 105 6e-22
AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) varia... 104 7e-22
AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein. 103 2e-21
D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein. 101 9e-21
AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein. 101 9e-21
AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein. 101 9e-21
AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein. 100 3e-20
BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein. 99 5e-20
AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. 99 5e-20
AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophil... 99 5e-20
AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. 99 5e-20
AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein pr... 99 5e-20
AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. 99 5e-20
AB209121-1|BAD92358.1| 620|Homo sapiens Mutant p53 binding prot... 99 5e-20
U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homol... 98 6e-20
M17778-1|AAA36799.1| 640|Homo sapiens protein ( Human uromoduli... 97 1e-19
M15881-1|AAA36798.1| 640|Homo sapiens protein ( Human uromoduli... 97 1e-19
AY162970-1|AAO64446.1| 640|Homo sapiens uromodulin precursor pr... 97 1e-19
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 97 1e-19
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 97 1e-19
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 97 1e-19
X05495-1|CAA29045.1| 575|Homo sapiens thrombomodulin protein. 96 3e-19
M16552-1|AAB59508.1| 575|Homo sapiens THBD protein. 96 3e-19
J02973-1|AAA61175.1| 575|Homo sapiens THBD protein. 96 3e-19
D00210-1|BAA00149.1| 575|Homo sapiens thrombomodulin precursor ... 96 3e-19
BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein. 96 3e-19
BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein. 96 3e-19
BC053357-1|AAH53357.1| 575|Homo sapiens thrombomodulin protein. 96 3e-19
BC035602-1|AAH35602.2| 575|Homo sapiens thrombomodulin protein. 96 3e-19
AL049651-2|CAB51954.1| 575|Homo sapiens thrombomodulin protein. 96 3e-19
AF495471-1|AAM03232.1| 575|Homo sapiens thrombomodulin protein. 96 3e-19
AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 96 3e-19
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 96 3e-19
AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 96 3e-19
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt... 96 3e-19
AB231861-1|BAE19679.1| 1950|Homo sapiens low-density lipoprotein... 91 1e-17
AB084910-1|BAD83615.1| 1905|Homo sapiens low density lipoprotein... 91 1e-17
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 90 2e-17
AC093039-1|AAX88911.1| 425|Homo sapiens unknown protein. 90 2e-17
BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 89 3e-17
BC077719-1|AAH77719.1| 219|Homo sapiens VWCE protein protein. 89 4e-17
BC052564-1|AAH52564.1| 219|Homo sapiens VWCE protein protein. 89 4e-17
BC042143-1|AAH42143.1| 237|Homo sapiens VWCE protein protein. 89 4e-17
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 89 4e-17
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres... 89 4e-17
AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isofor... 89 5e-17
BC035975-1|AAH35975.1| 611|Homo sapiens UMOD protein protein. 88 9e-17
AC020594-1|AAY15036.1| 150|Homo sapiens unknown protein. 87 1e-16
BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 87 2e-16
AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 87 2e-16
AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 87 2e-16
U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein. 86 3e-16
BC060770-1|AAH60770.2| 757|Homo sapiens SUSD1 protein protein. 85 6e-16
AY358746-1|AAQ89106.1| 747|Homo sapiens GRGP2438 protein. 85 6e-16
AL158824-3|CAI12348.2| 705|Homo sapiens sushi domain containing... 85 6e-16
AL158824-2|CAI12347.2| 747|Homo sapiens sushi domain containing... 85 6e-16
AL138756-2|CAI95300.2| 705|Homo sapiens sushi domain containing... 85 6e-16
AL138756-1|CAI95299.2| 747|Homo sapiens sushi domain containing... 85 6e-16
BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein. 85 8e-16
AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein. 85 8e-16
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 85 8e-16
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 85 8e-16
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 85 8e-16
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 85 8e-16
AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF re... 85 8e-16
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 85 8e-16
BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF re... 84 1e-15
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec... 83 3e-15
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein... 83 3e-15
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re... 83 3e-15
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein... 83 3e-15
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 83 3e-15
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 83 3e-15
BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein. 82 4e-15
BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein. 82 4e-15
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. 81 8e-15
S54426-1|AAB25244.1| 109|Homo sapiens fibrillin protein. 81 8e-15
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g... 81 8e-15
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g... 81 8e-15
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 81 8e-15
AF160476-1|AAF82398.1| 897|Homo sapiens CD44-like precursor FEL... 81 8e-15
AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein. 81 8e-15
BC050675-1|AAH50675.1| 353|Homo sapiens cysteine-rich with EGF-... 81 1e-14
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 81 1e-14
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 81 1e-14
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 81 1e-14
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 81 1e-14
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 81 1e-14
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 81 1e-14
DQ470680-1|ABF06672.1| 373|Homo sapiens CRELD2-zeta protein. 81 1e-14
DQ470678-1|ABF06670.1| 353|Homo sapiens CRELD2-delta protein. 81 1e-14
AY358355-1|AAQ88721.1| 353|Homo sapiens RLPR185 protein. 81 1e-14
BC131763-1|AAI31764.1| 581|Homo sapiens matrilin 4 protein. 80 2e-14
AL021578-3|CAB39280.1| 581|Homo sapiens matrilin 4 protein. 80 2e-14
AJ007581-1|CAA07569.1| 581|Homo sapiens matrilin-4 protein. 80 2e-14
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 80 2e-14
AB058677-1|BAB47410.1| 969|Homo sapiens MEGF11 protein (KIAA178... 79 4e-14
BC126440-1|AAI26441.1| 321|Homo sapiens OIT3 protein protein. 79 5e-14
AY358339-1|AAQ88705.1| 545|Homo sapiens PPFL826 protein. 79 5e-14
AY013707-1|AAG40096.2| 545|Homo sapiens LZP protein. 79 5e-14
AK096435-1|BAC04788.1| 545|Homo sapiens protein ( Homo sapiens ... 79 5e-14
BC050456-1|AAH50456.1| 961|Homo sapiens thrombospondin 4 protein. 78 1e-13
AY566253-1|AAS66982.1| 961|Homo sapiens thrombospondin 4 protein. 78 1e-13
U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein. 77 1e-13
BC038242-1|AAH38242.1| 261|Homo sapiens Similar to RIKEN cDNA 1... 77 1e-13
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 77 1e-13
DQ470679-1|ABF06671.1| 402|Homo sapiens CRELD2-epsilon protein. 77 2e-13
L32137-1|AAA57253.1| 757|Homo sapiens matrix protein protein. 76 3e-13
BC125092-1|AAI25093.1| 757|Homo sapiens cartilage oligomeric ma... 76 3e-13
BC110847-1|AAI10848.1| 757|Homo sapiens cartilage oligomeric ma... 76 3e-13
BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophil... 76 3e-13
AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein. 76 3e-13
AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein. 76 3e-13
AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein. 76 3e-13
AC003107-1|AAB86501.1| 817|Homo sapiens COMP_HUMAN protein. 76 3e-13
AB086984-1|BAC53888.1| 757|Homo sapiens cartilage oligomeric ma... 76 3e-13
AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein. 76 3e-13
AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2 pr... 76 3e-13
CR457380-1|CAG33661.1| 422|Homo sapiens CRELD1 protein. 76 4e-13
Z19585-1|CAA79635.1| 961|Homo sapiens thrombospondin-4 protein. 75 5e-13
S73849-1|AAB31735.1| 873|Homo sapiens very low density lipoprot... 75 5e-13
L22431-1|AAA61344.1| 873|Homo sapiens very low density lipoprot... 75 5e-13
D16532-1|BAA03969.1| 873|Homo sapiens very low density lipoprot... 75 5e-13
D16494-1|BAA03946.1| 845|Homo sapiens very low density lipoprot... 75 5e-13
D16493-1|BAA03945.1| 873|Homo sapiens very low density lipoprot... 75 5e-13
DQ067198-1|AAY46157.1| 873|Homo sapiens very low density lipopr... 75 5e-13
AL450467-4|CAH72455.1| 845|Homo sapiens very low density lipopr... 75 5e-13
AL450467-3|CAH72454.1| 873|Homo sapiens very low density lipopr... 75 5e-13
AB208822-1|BAD92059.1| 555|Homo sapiens Very low-density lipopr... 75 5e-13
BC008720-1|AAH08720.1| 422|Homo sapiens cysteine-rich with EGF-... 74 1e-12
AY358363-1|AAQ88729.1| 420|Homo sapiens CRELD1 protein. 74 1e-12
AK223216-1|BAD96936.1| 757|Homo sapiens cartilage oligomeric ma... 74 1e-12
AF452623-1|AAM75206.1| 420|Homo sapiens cysteine-rich with EGF-... 74 1e-12
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 74 2e-12
AK074396-1|BAB85069.1| 220|Homo sapiens protein ( Homo sapiens ... 73 2e-12
AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein. 73 2e-12
X84700-1|CAA59173.1| 742|Homo sapiens leucocyte antigen CD97 pr... 73 3e-12
L20470-1|AAA53684.1| 873|Homo sapiens very low density lipoprot... 73 3e-12
BC026690-1|AAH26690.1| 742|Homo sapiens CD97 molecule protein. 73 3e-12
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 73 3e-12
AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multip... 72 6e-12
AY280362-1|AAP35084.1| 2386|Homo sapiens EGF domain-containing p... 71 8e-12
AB011541-1|BAA32469.2| 2785|Homo sapiens MEGF8 protein. 71 8e-12
X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein. 71 1e-11
BC110320-1|AAI10321.1| 383|Homo sapiens EGF-like-domain, multip... 71 1e-11
AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein. 71 1e-11
AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multip... 71 1e-11
L00352-1|AAA56833.1| 860|Homo sapiens low density lipoprotein r... 70 2e-11
BT007361-1|AAP36025.1| 860|Homo sapiens low density lipoprotein... 70 2e-11
BC014514-1|AAH14514.1| 860|Homo sapiens low density lipoprotein... 70 2e-11
AY324609-1|AAP72971.1| 860|Homo sapiens low density lipoprotein... 70 2e-11
AY114155-1|AAM56036.1| 860|Homo sapiens low density lipoprotein... 70 2e-11
AF217403-1|AAF24515.1| 837|Homo sapiens low density lipoprotein... 70 2e-11
AB209409-1|BAD92646.1| 870|Homo sapiens low density lipoprotein... 70 2e-11
AF283342-1|AAL38107.1| 881|Homo sapiens candidate tumor suppres... 70 3e-11
X71923-1|CAA50739.1| 750|Homo sapiens tenascin-X precursor prot... 69 3e-11
U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein. 69 3e-11
AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein. 69 3e-11
AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein. 69 3e-11
AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein. 69 3e-11
AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein. 69 3e-11
AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein. 69 3e-11
AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB... 69 3e-11
AB011540-1|BAA32468.1| 1576|Homo sapiens MEGF7 protein. 69 3e-11
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 69 6e-11
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 69 6e-11
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 69 6e-11
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 69 6e-11
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 68 8e-11
AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar t... 68 8e-11
AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar t... 68 8e-11
M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein. 68 1e-10
D86407-1|BAA21824.1| 963|Homo sapiens ApoER2 protein. 68 1e-10
D50678-1|BAA09328.1| 963|Homo sapiens apolipoprotein E receptor... 68 1e-10
AB210038-1|BAE06120.1| 2233|Homo sapiens TNC variant protein pro... 68 1e-10
L38969-1|AAC41762.1| 956|Homo sapiens thrombospondin 3 protein. 67 1e-10
BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3, precu... 67 1e-10
AL713999-15|CAI95084.1| 956|Homo sapiens thrombospondin 3 protein. 67 1e-10
AK223278-1|BAD96998.1| 956|Homo sapiens thrombospondin 3 precur... 67 1e-10
AF023268-6|AAC51818.1| 736|Homo sapiens thrombospondin3 protein. 67 1e-10
X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein. 66 2e-10
BC105633-1|AAI05634.1| 757|Homo sapiens tumor endothelial marke... 66 2e-10
BC104484-1|AAI04485.1| 757|Homo sapiens tumor endothelial marke... 66 2e-10
BC051836-1|AAH51836.2| 904|Homo sapiens low density lipoprotein... 66 2e-10
BC051340-1|AAH51340.1| 757|Homo sapiens CD248 molecule, endosia... 66 2e-10
AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachio... 66 2e-10
AJ295846-1|CAC34381.1| 757|Homo sapiens endosialin protein prot... 66 2e-10
AF279142-1|AAG00867.1| 757|Homo sapiens tumor endothelial marke... 66 2e-10
AC068287-1|AAY24318.1| 223|Homo sapiens unknown protein. 66 2e-10
BC141811-1|AAI41812.1| 540|Homo sapiens matrilin 4 protein. 66 3e-10
AK074597-1|BAC11083.1| 540|Homo sapiens protein ( Homo sapiens ... 66 3e-10
AK074595-1|BAC11081.1| 488|Homo sapiens protein ( Homo sapiens ... 66 3e-10
DQ470676-1|ABF06668.1| 321|Homo sapiens CRELD2-alpha protein. 65 5e-10
BC002894-1|AAH02894.1| 321|Homo sapiens CRELD2 protein protein. 65 5e-10
AL606760-4|CAI18908.1| 963|Homo sapiens low density lipoprotein... 65 5e-10
AL606760-2|CAI18910.1| 904|Homo sapiens low density lipoprotein... 65 5e-10
AL355483-2|CAI22780.1| 904|Homo sapiens low density lipoprotein... 65 5e-10
AL355483-1|CAI22781.1| 963|Homo sapiens low density lipoprotein... 65 5e-10
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 64 2e-09
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 64 2e-09
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 64 2e-09
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 64 2e-09
BX640729-1|CAE45845.1| 674|Homo sapiens hypothetical protein pr... 63 3e-09
BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein. 63 3e-09
AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1 (Droso... 63 3e-09
AK126775-1|BAC86684.1| 952|Homo sapiens protein ( Homo sapiens ... 62 4e-09
AB024578-1|BAA88952.1| 78|Homo sapiens notch4 protein. 62 4e-09
AL834326-1|CAD38994.1| 626|Homo sapiens hypothetical protein pr... 62 7e-09
AB052957-1|BAC15607.1| 803|Homo sapiens soluble form FELE-1 pro... 62 7e-09
AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein. 61 9e-09
D86407-2|BAA21825.1| 793|Homo sapiens ApoER2delta4-7 protein. 61 1e-08
AY358903-1|AAQ89262.1| 273|Homo sapiens VEMF protein. 61 1e-08
AY358347-1|AAQ88713.1| 406|Homo sapiens VPPP1921 protein. 61 1e-08
AL590226-1|CAH71721.1| 273|Homo sapiens EGF-like-domain, multip... 61 1e-08
AF186111-1|AAF01429.1| 273|Homo sapiens NOTCH4-like protein pro... 61 1e-08
AB075863-1|BAB85569.1| 418|Homo sapiens KIAA1983 protein protein. 61 1e-08
BC088371-1|AAH88371.1| 273|Homo sapiens EGF-like-domain, multip... 60 2e-08
BC012377-1|AAH12377.1| 273|Homo sapiens EGF-like-domain, multip... 60 2e-08
AY358902-1|AAQ89261.1| 273|Homo sapiens VEMF protein. 60 2e-08
AY358901-1|AAQ89260.1| 273|Homo sapiens VEMF protein. 60 2e-08
AB125649-1|BAD01469.1| 273|Homo sapiens VE-statin protein. 60 2e-08
X55077-1|CAA38905.1| 591|Homo sapiens alpha-2 macroglobulin rec... 60 2e-08
BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein pr... 60 2e-08
BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. 60 2e-08
BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosop... 60 2e-08
AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosop... 60 2e-08
AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosop... 60 2e-08
AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein pr... 60 2e-08
AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens ... 60 2e-08
BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. 60 3e-08
BC072015-1|AAH72015.1| 296|Homo sapiens LRP1 protein protein. 60 3e-08
BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosop... 60 3e-08
BC052593-1|AAH52593.1| 296|Homo sapiens LRP1 protein protein. 60 3e-08
BC045107-1|AAH45107.1| 292|Homo sapiens LRP1 protein protein. 60 3e-08
BC021204-1|AAH21204.1| 439|Homo sapiens LRP1 protein protein. 60 3e-08
BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-termi... 60 3e-08
AC019195-1|AAY14953.1| 546|Homo sapiens unknown protein. 60 3e-08
AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein. 59 4e-08
BX322234-1|CAI23645.1| 1172|Homo sapiens thrombospondin 2 protein. 59 5e-08
Z75190-1|CAA99509.1| 699|Homo sapiens apolipoprotein E receptor... 58 6e-08
X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F... 58 6e-08
L12350-1|AAA03703.1| 1172|Homo sapiens thrombospondin 2 protein. 58 6e-08
AL606760-3|CAI18909.1| 700|Homo sapiens low density lipoprotein... 58 6e-08
AL355483-3|CAI22782.1| 700|Homo sapiens low density lipoprotein... 58 6e-08
AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens ... 58 6e-08
BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophil... 58 8e-08
AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor ... 58 8e-08
AL450467-2|CAH72453.1| 752|Homo sapiens very low density lipopr... 58 1e-07
AK092381-1|BAC03874.1| 752|Homo sapiens protein ( Homo sapiens ... 58 1e-07
U15981-1|AAA75365.1| 310|Homo sapiens dlk protein. 57 1e-07
AY358360-1|AAQ88726.1| 690|Homo sapiens ETL protein. 57 1e-07
AL596269-1|CAI13205.1| 690|Homo sapiens EGF, latrophilin and se... 57 1e-07
AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multip... 57 1e-07
AB032017-1|BAD83584.1| 690|Homo sapiens KPG_003 protein protein. 57 1e-07
U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged pr... 57 2e-07
Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein... 56 3e-07
U15979-1|AAA75364.1| 382|Homo sapiens dlk protein. 56 3e-07
DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein. 56 3e-07
DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein. 56 3e-07
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. 56 3e-07
D86864-1|BAA24070.1| 830|Homo sapiens acetyl LDL receptor protein. 56 3e-07
D63483-1|BAA09770.1| 830|Homo sapiens KIAA0149 protein. 56 3e-07
BC039735-1|AAH39735.1| 830|Homo sapiens scavenger receptor clas... 56 3e-07
>AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital
contractural arachnodactyly) variant protein.
Length = 1976
Score = 457 bits (1126), Expect = e-128
Identities = 208/449 (46%), Positives = 260/449 (57%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NEC AFPG+C +G+CRN +G F C C G+ D + C D++EC I +CG G C
Sbjct: 137 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 196
Query: 178 NTEGSFTCHCRPGYKADDFS-KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C GY++ K C+DIDEC N LCRGG CVNT GSF+C+C G EL+
Sbjct: 197 NTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELS 256
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
P R C DI+ECS++ +C NG C N +GTYQC C+ GY + +
Sbjct: 257 PSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGG 316
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C C N+ GSY C+C EG+ L DGRSC DIDEC C GGQC N G Y C C D
Sbjct: 317 CDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYD 376
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A+ TC D++EC DL S I C G C NT GSF+C
Sbjct: 377 GFM--ASMDMKTCIDVNEC-DLNSNI-------------------CMFGECENTKGSFIC 414
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GYSVK + CTD DECE+G +C A C+N+PGSF+C CR+GW G+G C D+
Sbjct: 415 HCQLGYSVK-KGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDL 473
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC C A C NT GS+RC C G+ GDG ++C D+DECA + LC
Sbjct: 474 DECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDG---------FTCSDVDECAENINLC 524
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
ENG C N PG Y C+C++GFT A+D RSC
Sbjct: 525 ENGQCLNVPGAYRCECEMGFTPASDSRSC 553
Score = 309 bits (758), Expect = 2e-83
Identities = 168/454 (37%), Positives = 223/454 (49%), Gaps = 42/454 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+++EC P LC G C N G F CDC G+E CVD+NEC + D +C +G C
Sbjct: 221 MDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKC 280
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G++ C C PGY+A + C DIDEC + C +C N+ GS+ C C G L
Sbjct: 281 VNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGC-DTQCTNSEGSYECSCSEGYALM 339
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
PD SC DIDEC IC G C N G Y+C+C +G+ S
Sbjct: 340 PDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNI 399
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTC 354
C C NT GS+ C C+ G+ ++ C D+DEC GA C C N GS+ C+C
Sbjct: 400 CMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 459
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
+G + + G K C D+DEC++ Q S++ Q C NT GS+
Sbjct: 460 REGWIGN--GIK--CIDLDECSN----------GTHQCSINAQ---------CVNTPGSY 496
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C C +G++ G C+D DEC C C+N+PG+++C C G+ D +
Sbjct: 497 RCACSEGFT---GDGFTCSDVDECAENINLCE-NGQCLNVPGAYRCECEMGFTPASDSRS 552
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C+D+DEC N TC N G F C+CD GY+ D G +C DIDECA D
Sbjct: 553 CQDIDECSFQN--ICVFGTCNNLPGMFHCICDDGYELDRTG-------GNCTDIDECA-D 602
Query: 533 PTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P C NG C NTPG YEC+C F G C+
Sbjct: 603 PINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCV 636
Score = 279 bits (683), Expect = 3e-74
Identities = 170/465 (36%), Positives = 224/465 (48%), Gaps = 39/465 (8%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNT 179
NEC P +C HG C +L G + C C G++ C+DV+ECE CG+G C NT
Sbjct: 958 NECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECE--RHPCGNGTCKNT 1015
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADN-DALCRGGRCVNTAGSFRCECGHGMELAPD 238
GS+ C C PG++ + C+DIDEC+ +CR GRC N GSF+C C G EL PD
Sbjct: 1016 VGSYNCLCYPGFELTH-NNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPD 1074
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR-C 297
+C D +EC G CS G C+N G+++C+C GY VKS C
Sbjct: 1075 GKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGY---EVKSENCIDINECDEDPNIC 1131
Query: 298 QH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDE--CAGGAR--PCGGGQCRNTVGSYTC 352
SC NTPG + C C G+ L +GR C D + C C + NT + C
Sbjct: 1132 LFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKA-KC 1190
Query: 353 TCTDGLVPSAAGAKP--TCQDIDECA--DL--ISTIIMMSVDELQKSVDP--QIPELCGA 404
C+ +P P C DE A DL + S+ + ++ V+ + P +C
Sbjct: 1191 CCSK--MPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSN 1248
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
G C NT GSF C+CP GY++ G C D DEC +G C C N+ GSF+C C +
Sbjct: 1249 GQCINTDGSFRCECPMGYNL-DYTGVRCVDTDECSIGN-PCGNGT-CTNVIGSFECNCNE 1305
Query: 465 GWR-GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
G+ G CED++EC N C R C NT GS+ C C GY LR C
Sbjct: 1306 GFEPGPMMNCEDINECAQNPLLCAFR--CMNTFGSYECTCPI-----GYALRE--DQKMC 1356
Query: 524 VDIDECANDPTLCENG--HCSNTPGGYECDCDVGFTRAADGRSCL 566
D+DECA CE+ C N G + C C G R DG C+
Sbjct: 1357 KDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCV 1401
Score = 272 bits (668), Expect = 2e-72
Identities = 161/459 (35%), Positives = 211/459 (45%), Gaps = 28/459 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC PG+C +G+C N G F C+C GY D CVD +EC I CG+G C
Sbjct: 1235 DVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI-GNPCGNGTCT 1293
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N GSF C+C G++ C DI+ECA N LC RC+NT GS+ C C G L
Sbjct: 1294 NVIGSFECNCNEGFEPGPMMN-CEDINECAQNPLLC-AFRCMNTFGSYECTCPIGYALRE 1351
Query: 238 DRLSCKDIDECSITSGIC-SNG-ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D+ CKD+DEC+ C S G C+N +GT+ C+C G A+
Sbjct: 1352 DQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPG 1411
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDE--CAGGARP--CG-GGQCRNTVGS 349
C++ CVN GSY C C EG+ + G C D + C C RN V
Sbjct: 1412 ICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTK 1471
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
C C G + + + D +P LC G C N
Sbjct: 1472 SECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCIN 1531
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--R 467
T+GSF C C GY+ G +C D DEC C+ C N GS+QC C G+ +
Sbjct: 1532 TMGSFRCFCKVGYTT-DISGTSCIDLDECSQSPKPCNYI--CKNTEGSYQCSCPRGYVLQ 1588
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
DG TC+D+DEC T C + C NT G F C C G+ +C+D +
Sbjct: 1589 EDGKTCKDLDECQTKQHNC--QFLCVNTLGGFTCKCPPGFTQHH---------TACIDNN 1637
Query: 528 ECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
EC + P+LC G C NTPG + C+C GF+ A G +C
Sbjct: 1638 ECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNC 1676
Score = 260 bits (638), Expect = 7e-69
Identities = 163/475 (34%), Positives = 225/475 (47%), Gaps = 73/475 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGD 175
++++EC PG+C +G C N +G F C+C G+ + C D++EC D +C + D
Sbjct: 871 VDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNAD 930
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N+ GS+ C C G+K + CVD +EC + +C G CV+ GS++C C +G +
Sbjct: 931 CINSPGSYRCECAAGFKLSP-NGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKA 989
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D+ C D+DEC C NG C+N +G+Y C+C G+ +
Sbjct: 990 SQDQTMCMDVDECE--RHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQ 1047
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C++ C N GS+ C C EG+ L DG++C D +EC C G C+N GS+ C C
Sbjct: 1048 VCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCIC 1107
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + C DI+EC DE DP I C GSC NT G F
Sbjct: 1108 PPGYEVKS----ENCIDINEC------------DE-----DPNI---CLFGSCTNTPGGF 1143
Query: 415 VCQCPDGYSVKPEQGPACTDDDE--C----ELGTCDCHPAAD-------CINLPG----- 456
C CP G+ V + G C D + C E G C A + C +PG
Sbjct: 1144 QCLCPPGF-VLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGD 1202
Query: 457 -----------SFQCRCRDGWRGDGA---TCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+FQ C G + T EDV+ECL + G C C NTDGSFRC
Sbjct: 1203 PCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGIC-SNGQCINTDGSFRCE 1261
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECA-NDPTLCENGHCSNTPGGYECDCDVGF 556
C GY D G+R CVD DEC+ +P C NG C+N G +EC+C+ GF
Sbjct: 1262 CPMGYNLDYTGVR-------CVDTDECSIGNP--CGNGTCTNVIGSFECNCNEGF 1307
Score = 256 bits (627), Expect = 2e-67
Identities = 158/467 (33%), Positives = 217/467 (46%), Gaps = 34/467 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC P +C G+C N+ G + C C+ G+ TC+DVNEC++ +C G+C
Sbjct: 347 DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECE 406
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC+ GY + C D+DEC C C+N GSF+C C G
Sbjct: 407 NTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW--I 464
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ + C D+DECS + CS N C N G+Y+C C EG+
Sbjct: 465 GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINL- 523
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C++ C+N PG+Y C C G+ +D RSC+DIDEC+ C G C N G + C C
Sbjct: 524 -CENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSF-QNICVFGTCNNLPGMFHCIC 581
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD-----ELQKSVDPQIPELCGAGSCHN 409
DG G C DIDECAD I+ + + V+ E D Q+ G G N
Sbjct: 582 DDGYELDRTGGN--CTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPT-GVGCVDN 638
Query: 410 TIGSFVCQC-PDG---YSVKPEQGPACTDDDEC-ELGTCDCHPAADC--INLPGSFQ-CR 461
+G+ + P G S E G + C LG +P C +N + C
Sbjct: 639 RVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCP 698
Query: 462 CRDGWRGDGATC--EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
+G+R + T ED+DEC G C C NT GSF+C C GY L
Sbjct: 699 GGEGFRPNPITIILEDIDECQELPGLCQG-GNCINTFGSFQCECPQGYY-----LSEDTR 752
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ C DIDEC P +C G C NT G Y C C + + G +C+
Sbjct: 753 I--CEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCM 797
Score = 254 bits (623), Expect = 5e-67
Identities = 154/452 (34%), Positives = 213/452 (47%), Gaps = 58/452 (12%)
Query: 143 CDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVD 202
C PG+ D VD++EC+ + G+C +G C N GSF C C G+ +D +C D
Sbjct: 855 CGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCED 914
Query: 203 IDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACE 261
IDEC++ D LC R C+N+ GS+RCEC G +L+P+ +C D +EC +CS+G C
Sbjct: 915 IDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCV 973
Query: 262 NQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH-SCVNTPGSYHCTCREGWHLRA 320
+ G+YQC+C G+ S + C + +C NT GSY+C C G+ L
Sbjct: 974 DLQGSYQCICHNGFKAS--QDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFEL-T 1030
Query: 321 DGRSCRDIDECAG-GARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
C DIDEC+ + C G+C N +GS+ C C +G + G C D +EC L
Sbjct: 1031 HNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDG--KNCIDTNECVAL- 1087
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE 439
P C G+C N GSF C CP GY VK E C D +EC+
Sbjct: 1088 -------------------PGSCSPGTCQNLEGSFRCICPPGYEVKSEN---CIDINECD 1125
Query: 440 LGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVDE--CLTN--NGGCH-PRA-- 490
C C N PG FQC C G+ +G C D + C TN NG C P+A
Sbjct: 1126 EDPNIC-LFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFN 1184
Query: 491 ------TCANTDG-SFRCLCDTGYKGD--------GYGLRTVCCVYSC-VDIDECANDPT 534
C+ G + C+ K D YG TV ++ D++EC P
Sbjct: 1185 TTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPG 1244
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C NG C NT G + C+C +G+ G C+
Sbjct: 1245 ICSNGQCINTDGSFRCECPMGYNLDYTGVRCV 1276
Score = 254 bits (622), Expect = 6e-67
Identities = 177/536 (33%), Positives = 224/536 (41%), Gaps = 75/536 (13%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWDRPID 65
C+ + V R+ CCCS LGKAWGN CE CP + Y LC G PN PI
Sbjct: 657 CNTEIGVGVSRSSCCCS-LGKAWGNP-CETCPPVNSTEYYTLCPG-GEGFRPN----PIT 709
Query: 66 GNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNECAAF 125
+ DI DE + G G N +++EC A
Sbjct: 710 IILEDI------DECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAH 763
Query: 126 PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVN-------------ECEIVDGVCG 172
PG+CG G C N LG +TC C P Y + + H C+D+ E E+ V
Sbjct: 764 PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTK 823
Query: 173 DGDC--HNTEGSFTCHCR--PGYKADDFSKICVDI---------------DECADNDALC 213
C +N ++ C P DF IC +I DEC + +C
Sbjct: 824 RMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGIC 883
Query: 214 RGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCD 272
G C+N GSFRCEC G L C+DIDECS +C N C N G+Y+C C
Sbjct: 884 ANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECA 943
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDEC 331
G+ S C H CV+ GSY C C G+ D C D+DEC
Sbjct: 944 AGFKLSP-NGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDEC 1002
Query: 332 AGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQ 391
PCG G C+NTVGSY C C G C DIDEC+
Sbjct: 1003 E--RHPCGNGTCKNTVGSYNCLCYPGF---ELTHNNDCLDIDECSSFFG----------- 1046
Query: 392 KSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
++C G C N IGSF C C +GY + P+ G C D +EC C P C
Sbjct: 1047 --------QVCRNGRCFNEIGSFKCLCNEGYELTPD-GKNCIDTNECVALPGSCSPGT-C 1096
Query: 452 INLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
NL GSF+C C G+ C D++EC + C +C NT G F+CLC G+
Sbjct: 1097 QNLEGSFRCICPPGYEVKSENCIDINECDEDPNIC-LFGSCTNTPGGFQCLCPPGF 1151
Score = 237 bits (579), Expect = 1e-61
Identities = 155/482 (32%), Positives = 213/482 (44%), Gaps = 71/482 (14%)
Query: 118 EVNECAAFPGLC-GHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
+++ECA C G C+NL+G F C C PG + CVD NEC G+C +G
Sbjct: 1358 DLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGR 1417
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDE--CADN--DALCR-GGRCVNTAGSFRCEC- 229
C N GS+ C C G+++ C+D + C +C+ N C C
Sbjct: 1418 CVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCD 1477
Query: 230 -----GHGMELAP------DRLSC----------KDIDECSITSGICSNGACENQMGTYQ 268
GH EL P + C +DIDEC + +C+NG C N MG+++
Sbjct: 1478 GGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFR 1537
Query: 269 CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDI 328
C C GY + C + C NT GSY C+C G+ L+ DG++C+D+
Sbjct: 1538 CFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDL 1597
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
DEC C C NT+G +TC C G C D +EC
Sbjct: 1598 DECQTKQHNCQF-LCVNTLGGFTCKCPPGFTQHHTA----CIDNNECGSQ---------- 1642
Query: 389 ELQKSVDPQIPELCGA-GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
P LCGA G C NT GSF C+C G+S+ G C D DEC+ G C
Sbjct: 1643 ----------PSLCGAKGICQNTPGSFSCECQRGFSLDAT-GLNCEDVDECD-GNHRCQH 1690
Query: 448 AADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
C N+ G ++C C G+ C D +EC +N C A+C NT GS++C C +
Sbjct: 1691 G--CQNILGGYRCGCPQGYIQHYQWNQCVDENEC-SNPNACGS-ASCYNTLGSYKCACPS 1746
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G+ D + +C D++EC++ C G CSNT GGY C C G+ R G
Sbjct: 1747 GFSFDQFSS-------ACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGYYRVGQGHCV 1798
Query: 566 LG 567
G
Sbjct: 1799 SG 1800
Score = 231 bits (565), Expect = 5e-60
Identities = 147/426 (34%), Positives = 196/426 (46%), Gaps = 63/426 (14%)
Query: 154 KNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC 213
K TC DVNECE+ GVC +G C N++GSF C C G D ++C+DI
Sbjct: 13 KGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDI---------- 62
Query: 214 RGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACEN--QMGT--YQC 269
R +C EC H + P + +D C G CE + GT Y+
Sbjct: 63 RMEQCYLKWD--EDECIHPV---PGKFR---MDACCCAVGAAWGTECEECPKPGTKEYET 114
Query: 270 VCDE--GYAQS----TVKSHXXXXXXXXXXXXRCQH-SCVNTPGSYHCTCREGWHLRADG 322
+C G+A T + C + C NT GS+ C C G+ L +
Sbjct: 115 LCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEE 174
Query: 323 RSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTI 382
R+C DIDEC CG G C NT GS+ C C +G S C DIDEC
Sbjct: 175 RNCTDIDECRISPDLCGSGICVNTPGSFECECFEG-YESGFMMMKNCMDIDEC------- 226
Query: 383 IMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGT 442
+ P LC G+C NT GSF C CP G+ + P + C D +EC L
Sbjct: 227 -------------ERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSR-EDCVDINECSLSD 272
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTDGSFR 500
C C+N+ G++QC C G++ D C D+DEC+ NGGC + C N++GS+
Sbjct: 273 NLCR-NGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQ--CTNSEGSYE 329
Query: 501 CLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAA 560
C C GY G SC DIDEC N+P +C+ G C+N PG Y C C GF +
Sbjct: 330 CSCSEGYALMPDG-------RSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASM 382
Query: 561 DGRSCL 566
D ++C+
Sbjct: 383 DMKTCI 388
Score = 231 bits (564), Expect = 7e-60
Identities = 152/468 (32%), Positives = 210/468 (44%), Gaps = 44/468 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++ +EC+ CG+G C N++G F C+C G+E + C D+NEC +C C
Sbjct: 1276 VDTDECS-IGNPCGNGTCTNVIGSFECNCNEGFEPGPMMN-CEDINECAQNPLLCAFR-C 1332
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECAD--NDALCRGGRCVNTAGSFRCECGHGME 234
NT GS+ C C GY + K+C D+DECA+ +D RG C N G+F C C GM
Sbjct: 1333 MNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMA 1392
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
PD C D +EC GIC NG C N +G+Y+C C+EG+ S+ +
Sbjct: 1393 RRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFA 1452
Query: 295 XRCQHSCVNTPGSYH------CTCREGWHLRADGRSCRDIDECAGGAR-----PCGGGQC 343
Q C S + C C G R G C ++ G A+ P G G
Sbjct: 1453 EVLQTICQMASSSRNLVTKSECCCDGG---RGWGHQC-ELCPLPGTAQYKKICPHGPGYT 1508
Query: 344 RNTVGSYTC-----TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQI 398
+ C CT+G + G+ + D IS + +DE +S
Sbjct: 1509 TDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTD-ISGTSCIDLDECSQS----- 1562
Query: 399 PELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
P+ C C NT GS+ C CP GY V E G C D DEC+ +C C+N G F
Sbjct: 1563 PKPCNY-ICKNTEGSYQCSCPRGY-VLQEDGKTCKDLDECQTKQHNCQFL--CVNTLGGF 1618
Query: 459 QCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C+C G+ C D +EC + C + C NT GSF C C G+ D GL
Sbjct: 1619 TCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGL---- 1674
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C D+DEC + C++G C N GGY C C G+ + C+
Sbjct: 1675 ---NCEDVDECDGNHR-CQHG-CQNILGGYRCGCPQGYIQHYQWNQCV 1717
Score = 229 bits (561), Expect = 2e-59
Identities = 157/490 (32%), Positives = 217/490 (44%), Gaps = 78/490 (15%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDV---------NECEIVD 168
+VNEC FPG+C +GRC N G F C+C G D C+D+ +E E +
Sbjct: 19 DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIH 78
Query: 169 GVCG----DGDCHNTEGSFTCHC----RPGYKADDFSKICVDIDECAD-NDAL------- 212
V G D C ++ C +PG K ++ +C A+ D L
Sbjct: 79 PVPGKFRMDACCCAVGAAWGTECEECPKPGTK--EYETLCPRGAGFANRGDVLTGRPFYK 136
Query: 213 ----CRG--GRCV-----NTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACE 261
C+ G C NT GSF+C C G L + +C DIDEC I+ +C +G C
Sbjct: 137 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 196
Query: 262 NQMGTYQCVCDEGYAQS-TVKSHXXXXXXXXXXXXRCQ-HSCVNTPGSYHCTCREGWHLR 319
N G+++C C EGY + + C+ +CVNT GS+ C C G L
Sbjct: 197 NTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELS 256
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
C DI+EC+ C G+C N +G+Y C+C G A + C DIDEC
Sbjct: 257 PSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGY--QATPDRQGCTDIDEC---- 310
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE 439
+IM + Q C N+ GS+ C C +GY++ P+ G +C D DECE
Sbjct: 311 --MIMNGGCDTQ---------------CTNSEGSYECSCSEGYALMPD-GRSCADIDECE 352
Query: 440 LGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTDG 497
D C N+PG ++C C DG+ D TC DV+EC N+ C C NT G
Sbjct: 353 -NNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNIC-MFGECENTKG 410
Query: 498 SFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGF 556
SF C C GY C D+DEC C+ + C N PG ++C C G+
Sbjct: 411 SFICHCQLGYS-------VKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW 463
Query: 557 TRAADGRSCL 566
+G C+
Sbjct: 464 --IGNGIKCI 471
Score = 229 bits (561), Expect = 2e-59
Identities = 142/418 (33%), Positives = 191/418 (45%), Gaps = 29/418 (6%)
Query: 153 SKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDAL 212
S + T DVNEC G+C +G C NT+GSF C C GY D CVD DEC+ +
Sbjct: 1228 SLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP- 1286
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
C G C N GSF C C G E P ++C+DI+EC+ +C+ C N G+Y+C C
Sbjct: 1287 CGNGTCTNVIGSFECNCNEGFEPGP-MMNCEDINECAQNPLLCAF-RCMNTFGSYECTCP 1344
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHLRADGRSCRDID 329
GYA + C+ C N G++ C C G R DG C D +
Sbjct: 1345 IGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDEN 1404
Query: 330 ECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC-ADLISTIIMMSVD 388
EC C G+C N +GSY C C +G S++G + C A+++ TI M+
Sbjct: 1405 ECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASS 1464
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKP--EQGPACTDD----DECELGT 442
+ G G H +C P K GP T D DEC++
Sbjct: 1465 SRNLVTKSECCCDGGRGWGHQ---CELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMP 1521
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGD--GATCEDVDECLTNNGGCHPRATCANTDGSFR 500
C CIN GSF+C C+ G+ D G +C D+DEC + C+ C NT+GS++
Sbjct: 1522 NLC-TNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCN--YICKNTEGSYQ 1578
Query: 501 CLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTR 558
C C GY G +C D+DEC C+ C NT GG+ C C GFT+
Sbjct: 1579 CSCPRGYVLQEDG-------KTCKDLDECQTKQHNCQ-FLCVNTLGGFTCKCPPGFTQ 1628
Score = 199 bits (486), Expect = 2e-50
Identities = 144/460 (31%), Positives = 197/460 (42%), Gaps = 49/460 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD--VNECEIVDGVCGDGD 175
+++ECA P C +G C N G + C+C P ++ + CVD V C + G GDG
Sbjct: 596 DIDECAD-PINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDG- 653
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFR-CECGHGME 234
S +C+ G S C + + N C VN+ + C G G
Sbjct: 654 ------SLSCNTEIGVGVSR-SSCCCSLGKAWGNP--CETCPPVNSTEYYTLCPGGEGFR 704
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
P + +DIDEC G+C G C N G++QC C +GY S
Sbjct: 705 PNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHP 764
Query: 295 XRC-QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN----TVGS 349
C +C NT G+Y C C + G +C D+ + + R G C N V
Sbjct: 765 GVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRK-SFCYRSYNGTTCENELPFNVTK 823
Query: 350 YTCTCTDGL------------VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
C CT + P A K C +I I T + +DE + +
Sbjct: 824 RMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECK-----E 878
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
IP +C G C N IGSF C+CP G+S + C D DEC G C ADCIN PGS
Sbjct: 879 IPGICANGVCINQIGSFRCECPTGFSYN-DLLLVCEDIDECSNGDNLCQRNADCINSPGS 937
Query: 458 FQCRCRDGWR-GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
++C C G++ C D +ECL C C + GS++C+C G+K +T
Sbjct: 938 YRCECAAGFKLSPNGACVDRNECLEIPNVC-SHGLCVDLQGSYQCICHNGFKASQD--QT 994
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
+ C+D+DEC P C NG C NT G Y C C GF
Sbjct: 995 M-----CMDVDECERHP--CGNGTCKNTVGSYNCLCYPGF 1027
Score = 194 bits (473), Expect = 7e-49
Identities = 148/472 (31%), Positives = 206/472 (43%), Gaps = 52/472 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGV-CGDGDC 176
+++EC+ F +C G C NL G F C C GYE D C D++EC D + C +G C
Sbjct: 555 DIDECS-FQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDEC--ADPINCVNGLC 611
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT G + C+C P ++ + CVD N L G R GS C G+ ++
Sbjct: 612 VNTPGRYECNCPPDFQLNPTGVGCVD--NRVGNCYLKFGPR---GDGSLSCNTEIGVGVS 666
Query: 237 PDRLSCKDIDECSITSGICSNGACEN----QMGTYQCVCD--EGYAQSTVKSHXXXXXXX 290
R SC CS+ G CE Y +C EG+ + +
Sbjct: 667 --RSSCC----CSL--GKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDEC 718
Query: 291 XXXXXRCQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
CQ +C+NT GS+ C C +G++L D R C DIDEC CG G C NT+G+
Sbjct: 719 QELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGN 778
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC--GAGSC 407
YTC C + G C D+ + S +EL +V ++ C G
Sbjct: 779 YTCICPPEYMQVNGGHN--CMDMRKSFCYRSYNGTTCENELPFNVTKRMC-CCTYNVGKA 835
Query: 408 HN-------TIGSF----VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPG 456
N T G+ +C G++ G A D DEC+ C CIN G
Sbjct: 836 WNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKA-VDIDECKEIPGICANGV-CINQIG 893
Query: 457 SFQCRCRDGWRGDGA--TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
SF+C C G+ + CED+DEC + C A C N+ GS+RC C G+K G
Sbjct: 894 SFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG- 952
Query: 515 RTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+CVD +EC P +C +G C + G Y+C C GF + D C+
Sbjct: 953 -------ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCM 997
Score = 171 bits (416), Expect = 6e-42
Identities = 87/242 (35%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC+ P C + C+N G + C C GY TC D++EC+ C C
Sbjct: 1554 IDLDECSQSPKPCNY-ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNC-QFLC 1611
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G FTC C PG+ + C+D +EC +LC G C NT GSF CEC G L
Sbjct: 1612 VNTLGGFTCKCPPGFTQHHTA--CIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSL 1669
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
L+C+D+DEC + C +G C+N +G Y+C C +GY Q +
Sbjct: 1670 DATGLNCEDVDECD-GNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA 1727
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
SC NT GSY C C G+ +C D++EC+ PC G C NT G Y C C
Sbjct: 1728 CGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCP 1786
Query: 356 DG 357
G
Sbjct: 1787 PG 1788
Score = 112 bits (269), Expect = 4e-24
Identities = 80/267 (29%), Positives = 110/267 (41%), Gaps = 33/267 (12%)
Query: 319 RADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
R G +C D++EC C G+C N+ GS+ C C +GL G C DI +
Sbjct: 11 RIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGR--VCLDI----RM 64
Query: 379 ISTIIMMSVDELQKSVDPQIPE---LCGAGSCHNT---------IGSFVCQCPDGYSVKP 426
+ DE V + C G+ T + CP G
Sbjct: 65 EQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFAN 124
Query: 427 EQG-----PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD--GATCEDVDEC 479
P D +EC+ C C N GSF+CRC G+ D C D+DEC
Sbjct: 125 RGDVLTGRPFYKDINECKAFPGMC-TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDEC 183
Query: 480 LTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG 539
+ C C NT GSF C C GY+ G+ + + +C+DIDEC +P LC G
Sbjct: 184 RISPDLC-GSGICVNTPGSFECECFEGYE-SGFMM-----MKNCMDIDECERNPLLCRGG 236
Query: 540 HCSNTPGGYECDCDVGFTRAADGRSCL 566
C NT G ++CDC +G + C+
Sbjct: 237 TCVNTEGSFQCDCPLGHELSPSREDCV 263
Score = 71.7 bits (168), Expect = 6e-12
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++ NEC+ P CG C N LG + C C G+ D + C DVNEC C G C
Sbjct: 1717 VDENECSN-PNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-C 1774
Query: 177 HNTEGSFTCHCRPGY 191
NTEG + C C PGY
Sbjct: 1775 SNTEGGYLCGCPPGY 1789
Score = 52.0 bits (119), Expect = 5e-06
Identities = 21/47 (44%), Positives = 30/47 (63%), Gaps = 2/47 (4%)
Query: 3 GGRCSGPLPTDVLRAVCCCSA-LGKAWGNQRCEPCPKKGTDAYQNLC 48
G C LP +V + +CCC+ +GKAW N+ CEPCP GT ++ +C
Sbjct: 810 GTTCENELPFNVTKRMCCCTYNVGKAW-NKPCEPCPTPGTADFKTIC 855
Score = 49.6 bits (113), Expect = 3e-05
Identities = 21/43 (48%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C P+P CCC A+G AWG + CE CPK GT Y+ LC
Sbjct: 76 CIHPVPGKFRMDACCC-AVGAAWGTE-CEECPKPGTKEYETLC 116
Score = 48.4 bits (110), Expect = 7e-05
Identities = 21/46 (45%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Query: 4 GRCSGPLPTDVLRAVCCCSAL-GKAWGNQRCEPCPKKGTDAYQNLC 48
G+CS P + +A CCCS + G+ WG+ CE CPK A+Q+LC
Sbjct: 1175 GKCSVPKAFNTTKAKCCCSKMPGEGWGDP-CELCPKDDEVAFQDLC 1219
Score = 40.7 bits (91), Expect = 0.013
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V ++ CCC G+ WG+Q CE CP GT Y+ +C
Sbjct: 1469 VTKSECCCDG-GRGWGHQ-CELCPLPGTAQYKKIC 1501
>X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein.
Length = 754
Score = 454 bits (1119), Expect = e-127
Identities = 208/451 (46%), Positives = 259/451 (57%), Gaps = 33/451 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NEC AFPG+C +G+CRN +G F C C G+ D + C D++EC I +CG G C
Sbjct: 321 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 380
Query: 178 NTEGSFTCHCRPGYKADDFS-KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C GY++ K C+DID C N LCRGG CVNT GSF+C+C G EL+
Sbjct: 381 NTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELS 440
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
P R C DI+ECS++ +C NG C N +GTYQC C+ GY + +
Sbjct: 441 PSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGG 500
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C C N+ GSY C+C EG+ L DGRSC DIDEC C GGQC N G Y C C D
Sbjct: 501 CDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYD 560
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A+ TC D++EC DL S I C G C NT GSF+C
Sbjct: 561 GFM--ASMDMKTCIDVNEC-DLNSNI-------------------CMFGECENTKGSFIC 598
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GYSVK + CTD DECE+G +C A C+N+PGSF+C CR+GW G+G C D
Sbjct: 599 HCQLGYSVK-KGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDR 657
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC C A C NT GS+RC C G+ GDG ++C D+DECA + LC
Sbjct: 658 DECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDG---------FTCSDVDECAENINLC 708
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
ENG C N PG Y C+C++GFT A+D RSC G
Sbjct: 709 ENGQCLNVPGAYRCECEMGFTPASDSRSCQG 739
Score = 232 bits (567), Expect = 3e-60
Identities = 126/362 (34%), Positives = 174/362 (48%), Gaps = 32/362 (8%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+++ C P LC G C N G F CDC G+E CVD+NEC + D +C +G C
Sbjct: 405 MDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKC 464
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G++ C C PGY+A + C DIDEC + C +C N+ GS+ C C G L
Sbjct: 465 VNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGC-DTQCTNSEGSYECSCSEGYALM 523
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
PD SC DIDEC IC G C N G Y+C+C +G+ S
Sbjct: 524 PDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNI 583
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTC 354
C C NT GS+ C C+ G+ ++ C D+DEC GA C C N GS+ C+C
Sbjct: 584 CMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 643
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
+G + + G K C D DEC++ Q S++ Q C NT GS+
Sbjct: 644 REGWIGN--GIK--CIDRDECSN----------GTHQCSINAQ---------CVNTPGSY 680
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C C +G++ G C+D DEC C C+N+PG+++C C G+ D +
Sbjct: 681 RCACSEGFT---GDGFTCSDVDECAENINLCE-NGQCLNVPGAYRCECEMGFTPASDSRS 736
Query: 473 CE 474
C+
Sbjct: 737 CQ 738
Score = 230 bits (562), Expect = 1e-59
Identities = 157/492 (31%), Positives = 218/492 (44%), Gaps = 78/492 (15%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDV---------NECEIVD 168
+VNEC FPG+C +GRC N G F C+C G D C+D+ +E E +
Sbjct: 203 DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIH 262
Query: 169 GVCG----DGDCHNTEGSFTCHC----RPGYKADDFSKICVDIDECAD-NDAL------- 212
V G D C ++ C +PG K ++ +C A+ D L
Sbjct: 263 PVPGKFRMDACCCAVGAAWGTECEECPKPGTK--EYETLCPRGAGFANRGDVLTGRPFYK 320
Query: 213 ----CRG--GRCV-----NTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACE 261
C+ G C NT GSF+C C G L + +C DIDEC I+ +C +G C
Sbjct: 321 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 380
Query: 262 NQMGTYQCVCDEGYAQS-TVKSHXXXXXXXXXXXXRCQ-HSCVNTPGSYHCTCREGWHLR 319
N G+++C C EGY + + C+ +CVNT GS+ C C G L
Sbjct: 381 NTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELS 440
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
C DI+EC+ C G+C N +G+Y C+C G A + C DIDEC
Sbjct: 441 PSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGY--QATPDRQGCTDIDEC---- 494
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE 439
+IM + Q C N+ GS+ C C +GY++ P+ G +C D DECE
Sbjct: 495 --MIMNGGCDTQ---------------CTNSEGSYECSCSEGYALMPD-GRSCADIDECE 536
Query: 440 LGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTDG 497
D C N+PG ++C C DG+ D TC DV+EC N+ C C NT G
Sbjct: 537 -NNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNIC-MFGECENTKG 594
Query: 498 SFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGF 556
SF C C GY C D+DEC C+ + C N PG ++C C G+
Sbjct: 595 SFICHCQLGYS-------VKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW 647
Query: 557 TRAADGRSCLGK 568
+G C+ +
Sbjct: 648 --IGNGIKCIDR 657
Score = 215 bits (525), Expect = 3e-55
Identities = 143/468 (30%), Positives = 200/468 (42%), Gaps = 55/468 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C+C GYE D+ C+D++EC + +C +G C
Sbjct: 16 DINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCR 75
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT GS++C C PGY ++ C DI+EC N C G C N GSF CEC G +L+
Sbjct: 76 NTPGSYSCTCPPGYVFRTETETCEDINECESNP--CVNGACRNNLGSFNCECSPGSKLSS 133
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
L C D G C + C+ +T+KS C
Sbjct: 134 TGLICID----------SLKGTC--WLNIQDSRCEVNINGATLKSE-CCATLGAAWGSPC 180
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+ ++T C G R G +C D++EC C G+C N+ GS+ C C +G
Sbjct: 181 ERCELDT------ACPRGL-ARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEG 233
Query: 358 LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPE---LCGAGSCHNT---- 410
L G C DI + + DE V + C G+ T
Sbjct: 234 LTLDGTGR--VCLDI----RMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEE 287
Query: 411 -----IGSFVCQCPDGYSVKPEQG-----PACTDDDECELGTCDCHPAADCINLPGSFQC 460
+ CP G P D +EC+ C C N GSF+C
Sbjct: 288 CPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMC-TYGKCRNTIGSFKC 346
Query: 461 RCRDGWRGD--GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
RC G+ D C D+DEC + C C NT GSF C C GY+ G+ +
Sbjct: 347 RCNSGFALDMEERNCTDIDECRISPDLC-GSGICVNTPGSFECECFEGYE-SGFMM---- 400
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ +C+DID C +P LC G C NT G ++CDC +G + C+
Sbjct: 401 -MKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCV 447
Score = 201 bits (491), Expect = 5e-51
Identities = 148/494 (29%), Positives = 206/494 (41%), Gaps = 66/494 (13%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC LC +G CRN G ++C C PGY ++ TC D+NECE C +G C
Sbjct: 57 IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECE--SNPCVNGAC 114
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDI--DECADN--DALCR--------GGRCVNTAGS 224
N GSF C C PG K IC+D C N D+ C C T G+
Sbjct: 115 RNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGA 174
Query: 225 F------RCE----CGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
RCE C G+ ++C+D++EC + G+C NG C N G++ C C EG
Sbjct: 175 AWGSPCERCELDTACPRGLARIKG-VTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEG 233
Query: 275 YAQSTVKSHXXXXXXXXXXXXRCQHSCVN-TPGSYH---CTCREGWHLRADGRSC----- 325
+ C++ PG + C C G + C
Sbjct: 234 LTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGT 293
Query: 326 RDIDE-CAGGARPCGGGQCR---------NTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
++ + C GA G N ++ CT G + G+ C+
Sbjct: 294 KEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSF-KCRCNSGF 352
Query: 376 ADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD 435
A + +DE + S P+LCG+G C NT GSF C+C +GY C D
Sbjct: 353 ALDMEERNCTDIDECRIS-----PDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDI 407
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCA 493
D CE C C+N GSFQC C G C D++EC ++ C C
Sbjct: 408 DGCERNPLLCR-GGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCR-NGKCV 465
Query: 494 NTDGSFRCLCDTGYKG--DGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
N G+++C C+ GY+ D G C DIDEC C+ C+N+ G YEC
Sbjct: 466 NMIGTYQCSCNPGYQATPDRQG---------CTDIDECMIMNGGCDT-QCTNSEGSYECS 515
Query: 552 CDVGFTRAADGRSC 565
C G+ DGRSC
Sbjct: 516 CSEGYALMPDGRSC 529
Score = 147 bits (356), Expect = 1e-34
Identities = 109/376 (28%), Positives = 160/376 (42%), Gaps = 57/376 (15%)
Query: 229 CGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXX 288
C G+ + D +DI+EC++ IC+NG CEN G+Y+C C+ GY +
Sbjct: 4 CSSGVGITVDG---RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDID 60
Query: 289 XXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTV 347
C + C NTPGSY CTC G+ R + +C DI+EC + PC G CRN +
Sbjct: 61 ECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECE--SNPCVNGACRNNL 118
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
GS+ C C+ G S+ G C D + +++ + + V+ L C
Sbjct: 119 GSFNCECSPGSKLSSTGL--------ICIDSLKGTCWLNIQDSRCEVNINGATL--KSEC 168
Query: 408 HNTIGS---FVCQ-------CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
T+G+ C+ CP G + +G C D +ECE+ C P C+N GS
Sbjct: 169 CATLGAAWGSPCERCELDTACPRG--LARIKGVTCEDVNECEVFPGVC-PNGRCVNSKGS 225
Query: 458 FQCRCRDGWR--GDGATCEDV-----------DECL-TNNGGCHPRATCANTDGSFRCLC 503
F C C +G G G C D+ DEC+ G A C ++ C
Sbjct: 226 FHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTEC 285
Query: 504 DTGYKGDGYGLRTVCCVYS--------------CVDIDECANDPTLCENGHCSNTPGGYE 549
+ K T+C + DI+EC P +C G C NT G ++
Sbjct: 286 EECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFK 345
Query: 550 CDCDVGFTRAADGRSC 565
C C+ GF + R+C
Sbjct: 346 CRCNSGFALDMEERNC 361
Score = 49.6 bits (113), Expect = 3e-05
Identities = 21/43 (48%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C P+P CCC A+G AWG + CE CPK GT Y+ LC
Sbjct: 260 CIHPVPGKFRMDACCC-AVGAAWGTE-CEECPKPGTKEYETLC 300
>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
Length = 2911
Score = 454 bits (1119), Expect = e-127
Identities = 207/449 (46%), Positives = 259/449 (57%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NEC AFPG+C +G+CRN +G F C C G+ D + C D++EC I +CG G C
Sbjct: 1072 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 1131
Query: 178 NTEGSFTCHCRPGYKADDFS-KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C GY++ K C+DID C N LCRGG CVNT GSF+C+C G EL+
Sbjct: 1132 NTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELS 1191
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
P R C DI+ECS++ +C NG C N +GTYQC C+ GY + +
Sbjct: 1192 PSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGG 1251
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C C N+ GSY C+C EG+ L DGRSC DIDEC C GGQC N G Y C C D
Sbjct: 1252 CDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYD 1311
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A+ TC D++EC DL S I C G C NT GSF+C
Sbjct: 1312 GFM--ASMDMKTCIDVNEC-DLNSNI-------------------CMFGECENTKGSFIC 1349
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GYSVK + CTD DECE+G +C A C+N+PGSF+C CR+GW G+G C D+
Sbjct: 1350 HCQLGYSVK-KGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDL 1408
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC C A C NT GS+RC C G+ GDG ++C D+DECA + LC
Sbjct: 1409 DECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDG---------FTCSDVDECAENINLC 1459
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
ENG C N PG Y C+C++GFT A+D RSC
Sbjct: 1460 ENGQCLNVPGAYRCECEMGFTPASDSRSC 1488
Score = 307 bits (753), Expect = 8e-83
Identities = 167/454 (36%), Positives = 222/454 (48%), Gaps = 42/454 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+++ C P LC G C N G F CDC G+E CVD+NEC + D +C +G C
Sbjct: 1156 MDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKC 1215
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G++ C C PGY+A + C DIDEC + C +C N+ GS+ C C G L
Sbjct: 1216 VNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGC-DTQCTNSEGSYECSCSEGYALM 1274
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
PD SC DIDEC IC G C N G Y+C+C +G+ S
Sbjct: 1275 PDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNI 1334
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTC 354
C C NT GS+ C C+ G+ ++ C D+DEC GA C C N GS+ C+C
Sbjct: 1335 CMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 1394
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
+G + + G K C D+DEC++ Q S++ Q C NT GS+
Sbjct: 1395 REGWIGN--GIK--CIDLDECSN----------GTHQCSINAQ---------CVNTPGSY 1431
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C C +G++ G C+D DEC C C+N+PG+++C C G+ D +
Sbjct: 1432 RCACSEGFT---GDGFTCSDVDECAENINLCE-NGQCLNVPGAYRCECEMGFTPASDSRS 1487
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C+D+DEC N TC N G F C+CD GY+ D G +C DIDECA D
Sbjct: 1488 CQDIDECSFQN--ICVSGTCNNLPGMFHCICDDGYELDRTG-------GNCTDIDECA-D 1537
Query: 533 PTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P C NG C NTPG YEC+C F G C+
Sbjct: 1538 PINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCV 1571
Score = 279 bits (684), Expect = 2e-74
Identities = 170/465 (36%), Positives = 224/465 (48%), Gaps = 39/465 (8%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNT 179
NEC P +C HG C +L G + C C G++ C+DV+ECE CG+G C NT
Sbjct: 1893 NECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECE--RHPCGNGTCKNT 1950
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADN-DALCRGGRCVNTAGSFRCECGHGMELAPD 238
GS+ C C PG++ + C+DIDEC+ +CR GRC N GSF+C C G EL PD
Sbjct: 1951 VGSYNCLCYPGFELTH-NNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPD 2009
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR-C 297
+C D +EC G CS G C+N G+++C+C GY VKS C
Sbjct: 2010 GKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGY---EVKSENCIDINECDEDPNIC 2066
Query: 298 QH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDE--CAGGAR--PCGGGQCRNTVGSYTC 352
SC NTPG + C C G+ L +GR C D + C C + NT + C
Sbjct: 2067 LFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKA-KC 2125
Query: 353 TCTDGLVPSAAGAKP--TCQDIDECA--DL--ISTIIMMSVDELQKSVDP--QIPELCGA 404
C+ +P P C DE A DL + S+ + ++ V+ + P +C
Sbjct: 2126 CCSK--MPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSN 2183
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
G C NT GSF C+CP GY++ G C D DEC +G C C N+ GSF+C C +
Sbjct: 2184 GQCINTDGSFRCECPMGYNL-DYTGVRCVDTDECSIGN-PCGNGT-CTNVIGSFECNCNE 2240
Query: 465 GWR-GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
G+ G CED++EC N C R C NT GS+ C C GY LR C
Sbjct: 2241 GFEPGPMMNCEDINECAQNPLLCALR--CMNTFGSYECTCPI-----GYALRE--DQKMC 2291
Query: 524 VDIDECANDPTLCENG--HCSNTPGGYECDCDVGFTRAADGRSCL 566
D+DECA CE+ C N G + C C G R DG C+
Sbjct: 2292 KDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCV 2336
Score = 271 bits (664), Expect = 5e-72
Identities = 161/459 (35%), Positives = 210/459 (45%), Gaps = 28/459 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC PG+C +G+C N G F C+C GY D CVD +EC I CG+G C
Sbjct: 2170 DVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI-GNPCGNGTCT 2228
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N GSF C+C G++ C DI+ECA N LC RC+NT GS+ C C G L
Sbjct: 2229 NVIGSFECNCNEGFEPGPMMN-CEDINECAQNPLLC-ALRCMNTFGSYECTCPIGYALRE 2286
Query: 238 DRLSCKDIDECSITSGIC-SNG-ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D+ CKD+DEC+ C S G C+N +GT+ C+C G A+
Sbjct: 2287 DQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPG 2346
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDE--CAGGARP--CG-GGQCRNTVGS 349
C++ CVN GSY C C EG+ + G C D + C C RN V
Sbjct: 2347 ICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTK 2406
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
C C G + + + D +P LC G C N
Sbjct: 2407 SECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCIN 2466
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--R 467
T+GSF C C GY+ G +C D DEC C+ C N GS+QC C G+ +
Sbjct: 2467 TMGSFRCFCKVGYTT-DISGTSCIDLDECSQSPKPCNYI--CKNTEGSYQCSCPRGYVLQ 2523
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
DG TC+D+DEC T C + C NT G F C C G+ +C+D +
Sbjct: 2524 EDGKTCKDLDECQTKQHNC--QFLCVNTLGGFTCKCPPGFTQHH---------TACIDNN 2572
Query: 528 ECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
EC + P LC G C NTPG + C+C GF+ A G +C
Sbjct: 2573 ECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNC 2611
Score = 269 bits (660), Expect = 2e-71
Identities = 170/536 (31%), Positives = 244/536 (45%), Gaps = 39/536 (7%)
Query: 1 MTGGRCSGPLPTDVLRAVCCCSALGKAWGNQRC-EPCPKKGTDAYQNLCIAVGTL--LPP 57
+ GRC+ LP + + CCC G+ WG E CP +G++ Y+ LC+ + +P
Sbjct: 369 LVNGRCAQELPGRMTKMQCCCEP-GRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPG 427
Query: 58 NQWDRPIDGNMTDIWSQVGGDENGDGYGKQW-------GENXXXXXXXXXXXXXXXXX-- 108
+ RP G + ++ G NG+GYG G N
Sbjct: 428 SAGSRP-GGTGGNGFAPSG---NGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPI 483
Query: 109 XXXXXXXQMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVD 168
++ C LC +GRC + + C+C GY++D+ N C+DV+EC
Sbjct: 484 ITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDA-NGDCIDVDEC--TS 540
Query: 169 GVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCE 228
C +GDC NT GS+ C C G++ + C+DIDEC N LC+ GRCVN+ GSF+C
Sbjct: 541 NPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCI 600
Query: 229 CGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXX 288
C G EL D +C D DEC+ T+ +C NG C N+ G+++C+C G+ + +
Sbjct: 601 CNAGFELTTDGKNCVDHDECT-TTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVD 659
Query: 289 XXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDI---DECAGGARPCGGGQC-R 344
C+N+ GS+ C C G + DGR C D C GG + G C R
Sbjct: 660 ECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKK---GVCVR 716
Query: 345 NTVGSYT---CTCTDGLVPSAAGAKP-TCQDIDECADLISTIIMMSVDELQKSVDPQIPE 400
G+ T C C + +P ++ E L S+ + ++VD + P+
Sbjct: 717 PFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPD 776
Query: 401 LCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC 460
+C G C N GS+ C C GY G C D DEC + C C N PGS+ C
Sbjct: 777 ICANGICENLRGSYRCNCNSGYE-PDASGRNCIDIDECLVNRLLCDNGL-CRNTPGSYSC 834
Query: 461 RCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
C G+ R + TCED++EC +N C C N GSF C C G K GL
Sbjct: 835 TCPPGYVFRTETETCEDINECESN--PC-VNGACRNNLGSFNCECSPGSKLSSTGL 887
Score = 261 bits (639), Expect = 5e-69
Identities = 178/536 (33%), Positives = 224/536 (41%), Gaps = 75/536 (13%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWDRPID 65
C+ + V R+ CCCS LGKAWGN CE CP + Y LC G PN PI
Sbjct: 1592 CNTEIGVGVSRSSCCCS-LGKAWGNP-CETCPPVNSTEYYTLCPG-GEGFRPN----PIT 1644
Query: 66 GNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNECAAF 125
+ DI DE + G G N +++EC A
Sbjct: 1645 IILEDI------DECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAH 1698
Query: 126 PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE-----------CE------IVD 168
PG+CG G C N LG +TC C P Y + + H C+D+ + CE +
Sbjct: 1699 PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTK 1758
Query: 169 GVCGDGDCHNTEGSFTCHCRPGYKADDFSKIC---------------VDIDECADNDALC 213
+C G+ C P DF IC VDIDEC + +C
Sbjct: 1759 RMCCCTYNVGKAGNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGIC 1818
Query: 214 RGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCD 272
G C+N GSFRCEC G L C+DIDECS +C N C N G+Y+C C
Sbjct: 1819 ANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECA 1878
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDEC 331
G+ S C H CV+ GSY C C G+ D C D+DEC
Sbjct: 1879 AGFKLSP-NGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDEC 1937
Query: 332 AGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQ 391
PCG G C+NTVGSY C C G C DIDEC+
Sbjct: 1938 E--RHPCGNGTCKNTVGSYNCLCYPGF---ELTHNNDCLDIDECSSFFG----------- 1981
Query: 392 KSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
++C G C N IGSF C C +GY + P+ G C D +EC C P C
Sbjct: 1982 --------QVCRNGRCFNEIGSFKCLCNEGYELTPD-GKNCIDTNECVALPGSCSPGT-C 2031
Query: 452 INLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
NL GSF+C C G+ C D++EC + C +C NT G F+CLC G+
Sbjct: 2032 QNLEGSFRCICPPGYEVKSENCIDINECDEDPNIC-LFGSCTNTPGGFQCLCPPGF 2086
Score = 260 bits (638), Expect = 7e-69
Identities = 163/475 (34%), Positives = 225/475 (47%), Gaps = 73/475 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGD 175
++++EC PG+C +G C N +G F C+C G+ + C D++EC D +C + D
Sbjct: 1806 VDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNAD 1865
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N+ GS+ C C G+K + CVD +EC + +C G CV+ GS++C C +G +
Sbjct: 1866 CINSPGSYRCECAAGFKLSP-NGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKA 1924
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D+ C D+DEC C NG C+N +G+Y C+C G+ +
Sbjct: 1925 SQDQTMCMDVDECE--RHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQ 1982
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C++ C N GS+ C C EG+ L DG++C D +EC C G C+N GS+ C C
Sbjct: 1983 VCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCIC 2042
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + C DI+EC DE DP I C GSC NT G F
Sbjct: 2043 PPGYEVKS----ENCIDINEC------------DE-----DPNI---CLFGSCTNTPGGF 2078
Query: 415 VCQCPDGYSVKPEQGPACTDDDE--C----ELGTCDCHPAAD-------CINLPG----- 456
C CP G+ V + G C D + C E G C A + C +PG
Sbjct: 2079 QCLCPPGF-VLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGD 2137
Query: 457 -----------SFQCRCRDGWRGDGA---TCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+FQ C G + T EDV+ECL + G C C NTDGSFRC
Sbjct: 2138 PCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGIC-SNGQCINTDGSFRCE 2196
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECA-NDPTLCENGHCSNTPGGYECDCDVGF 556
C GY D G+R CVD DEC+ +P C NG C+N G +EC+C+ GF
Sbjct: 2197 CPMGYNLDYTGVR-------CVDTDECSIGNP--CGNGTCTNVIGSFECNCNEGF 2242
Score = 257 bits (630), Expect = 7e-68
Identities = 158/467 (33%), Positives = 217/467 (46%), Gaps = 34/467 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC P +C G+C N+ G + C C+ G+ TC+DVNEC++ +C G+C
Sbjct: 1282 DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECE 1341
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC+ GY + C D+DEC C C+N GSF+C C G
Sbjct: 1342 NTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW--I 1399
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ + C D+DECS + CS N C N G+Y+C C EG+
Sbjct: 1400 GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINL- 1458
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C++ C+N PG+Y C C G+ +D RSC+DIDEC+ C G C N G + C C
Sbjct: 1459 -CENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSF-QNICVSGTCNNLPGMFHCIC 1516
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD-----ELQKSVDPQIPELCGAGSCHN 409
DG G C DIDECAD I+ + + V+ E D Q+ G G N
Sbjct: 1517 DDGYELDRTGGN--CTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPT-GVGCVDN 1573
Query: 410 TIGSFVCQC-PDG---YSVKPEQGPACTDDDEC-ELGTCDCHPAADC--INLPGSFQ-CR 461
+G+ + P G S E G + C LG +P C +N + C
Sbjct: 1574 RVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCP 1633
Query: 462 CRDGWRGDGATC--EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
+G+R + T ED+DEC G C C NT GSF+C C GY L
Sbjct: 1634 GGEGFRPNPITIILEDIDECQELPGLCQG-GNCINTFGSFQCECPQGYY-----LSEDTR 1687
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ C DIDEC P +C G C NT G Y C C + + G +C+
Sbjct: 1688 I--CEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCM 1732
Score = 254 bits (623), Expect = 5e-67
Identities = 154/452 (34%), Positives = 213/452 (47%), Gaps = 58/452 (12%)
Query: 143 CDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVD 202
C PG+ D VD++EC+ + G+C +G C N GSF C C G+ +D +C D
Sbjct: 1790 CGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCED 1849
Query: 203 IDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACE 261
IDEC++ D LC R C+N+ GS+RCEC G +L+P+ +C D +EC +CS+G C
Sbjct: 1850 IDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCV 1908
Query: 262 NQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH-SCVNTPGSYHCTCREGWHLRA 320
+ G+YQC+C G+ S + C + +C NT GSY+C C G+ L
Sbjct: 1909 DLQGSYQCICHNGFKAS--QDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFEL-T 1965
Query: 321 DGRSCRDIDECAG-GARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
C DIDEC+ + C G+C N +GS+ C C +G + G C D +EC L
Sbjct: 1966 HNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDG--KNCIDTNECVAL- 2022
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE 439
P C G+C N GSF C CP GY VK E C D +EC+
Sbjct: 2023 -------------------PGSCSPGTCQNLEGSFRCICPPGYEVKSEN---CIDINECD 2060
Query: 440 LGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVDE--CLTN--NGGCH-PRA-- 490
C C N PG FQC C G+ +G C D + C TN NG C P+A
Sbjct: 2061 EDPNIC-LFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFN 2119
Query: 491 ------TCANTDG-SFRCLCDTGYKGD--------GYGLRTVCCVYSC-VDIDECANDPT 534
C+ G + C+ K D YG TV ++ D++EC P
Sbjct: 2120 TTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPG 2179
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C NG C NT G + C+C +G+ G C+
Sbjct: 2180 ICSNGQCINTDGSFRCECPMGYNLDYTGVRCV 2211
Score = 234 bits (572), Expect = 7e-61
Identities = 154/482 (31%), Positives = 212/482 (43%), Gaps = 71/482 (14%)
Query: 118 EVNECAAFPGLC-GHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
+++ECA C G C+NL+G F C C PG + CVD NEC G+C +G
Sbjct: 2293 DLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGR 2352
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDE--CADN--DALCR-GGRCVNTAGSFRCEC- 229
C N GS+ C C G+++ C+D + C +C+ N C C
Sbjct: 2353 CVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCD 2412
Query: 230 -----GHGMELAP------DRLSC----------KDIDECSITSGICSNGACENQMGTYQ 268
GH EL P + C +DIDEC + +C+NG C N MG+++
Sbjct: 2413 GGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFR 2472
Query: 269 CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDI 328
C C GY + C + C NT GSY C+C G+ L+ DG++C+D+
Sbjct: 2473 CFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDL 2532
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
DEC C C NT+G +TC C G C D +EC
Sbjct: 2533 DECQTKQHNCQF-LCVNTLGGFTCKCPPGFTQHHTA----CIDNNECGSQ---------- 2577
Query: 389 ELQKSVDPQIPELCGA-GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
P LCG G C NT GSF C+C G+S+ G C D DEC+ G C
Sbjct: 2578 ----------PLLCGGKGICQNTPGSFSCECQRGFSLDAT-GLNCEDVDECD-GNHRCQH 2625
Query: 448 AADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
C N+ G ++C C G+ C D +EC +N C A+C NT GS++C C +
Sbjct: 2626 G--CQNILGGYRCGCPQGYIQHYQWNQCVDENEC-SNPNACGS-ASCYNTLGSYKCACPS 2681
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G+ D + +C D++EC++ C G CSNT GGY C C G+ R G
Sbjct: 2682 GFSFDQFSS-------ACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGYYRVGQGHCV 2733
Query: 566 LG 567
G
Sbjct: 2734 SG 2735
Score = 229 bits (561), Expect = 2e-59
Identities = 157/490 (32%), Positives = 217/490 (44%), Gaps = 78/490 (15%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDV---------NECEIVD 168
+VNEC FPG+C +GRC N G F C+C G D C+D+ +E E +
Sbjct: 954 DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIH 1013
Query: 169 GVCG----DGDCHNTEGSFTCHC----RPGYKADDFSKICVDIDECAD-NDAL------- 212
V G D C ++ C +PG K ++ +C A+ D L
Sbjct: 1014 PVPGKFRMDACCCAVGAAWGTECEECPKPGTK--EYETLCPRGAGFANRGDVLTGRPFYK 1071
Query: 213 ----CRG--GRCV-----NTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACE 261
C+ G C NT GSF+C C G L + +C DIDEC I+ +C +G C
Sbjct: 1072 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 1131
Query: 262 NQMGTYQCVCDEGYAQS-TVKSHXXXXXXXXXXXXRCQ-HSCVNTPGSYHCTCREGWHLR 319
N G+++C C EGY + + C+ +CVNT GS+ C C G L
Sbjct: 1132 NTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELS 1191
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
C DI+EC+ C G+C N +G+Y C+C G A + C DIDEC
Sbjct: 1192 PSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGY--QATPDRQGCTDIDEC---- 1245
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE 439
+IM + Q C N+ GS+ C C +GY++ P+ G +C D DECE
Sbjct: 1246 --MIMNGGCDTQ---------------CTNSEGSYECSCSEGYALMPD-GRSCADIDECE 1287
Query: 440 LGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTDG 497
D C N+PG ++C C DG+ D TC DV+EC N+ C C NT G
Sbjct: 1288 -NNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNIC-MFGECENTKG 1345
Query: 498 SFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGF 556
SF C C GY C D+DEC C+ + C N PG ++C C G+
Sbjct: 1346 SFICHCQLGYS-------VKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW 1398
Query: 557 TRAADGRSCL 566
+G C+
Sbjct: 1399 --IGNGIKCI 1406
Score = 229 bits (561), Expect = 2e-59
Identities = 142/418 (33%), Positives = 191/418 (45%), Gaps = 29/418 (6%)
Query: 153 SKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDAL 212
S + T DVNEC G+C +G C NT+GSF C C GY D CVD DEC+ +
Sbjct: 2163 SLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP- 2221
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
C G C N GSF C C G E P ++C+DI+EC+ +C+ C N G+Y+C C
Sbjct: 2222 CGNGTCTNVIGSFECNCNEGFEPGP-MMNCEDINECAQNPLLCAL-RCMNTFGSYECTCP 2279
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHLRADGRSCRDID 329
GYA + C+ C N G++ C C G R DG C D +
Sbjct: 2280 IGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDEN 2339
Query: 330 ECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC-ADLISTIIMMSVD 388
EC C G+C N +GSY C C +G S++G + C A+++ TI M+
Sbjct: 2340 ECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASS 2399
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKP--EQGPACTDD----DECELGT 442
+ G G H +C P K GP T D DEC++
Sbjct: 2400 SRNLVTKSECCCDGGRGWGHQ---CELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMP 2456
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGD--GATCEDVDECLTNNGGCHPRATCANTDGSFR 500
C CIN GSF+C C+ G+ D G +C D+DEC + C+ C NT+GS++
Sbjct: 2457 NLC-TNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCN--YICKNTEGSYQ 2513
Query: 501 CLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTR 558
C C GY G +C D+DEC C+ C NT GG+ C C GFT+
Sbjct: 2514 CSCPRGYVLQEDG-------KTCKDLDECQTKQHNCQ-FLCVNTLGGFTCKCPPGFTQ 2563
Score = 228 bits (558), Expect = 4e-59
Identities = 152/468 (32%), Positives = 210/468 (44%), Gaps = 44/468 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++ +EC+ CG+G C N++G F C+C G+E + C D+NEC +C C
Sbjct: 2211 VDTDECS-IGNPCGNGTCTNVIGSFECNCNEGFEPGPMMN-CEDINECAQNPLLCALR-C 2267
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECAD--NDALCRGGRCVNTAGSFRCECGHGME 234
NT GS+ C C GY + K+C D+DECA+ +D RG C N G+F C C GM
Sbjct: 2268 MNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMA 2327
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
PD C D +EC GIC NG C N +G+Y+C C+EG+ S+ +
Sbjct: 2328 RRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFA 2387
Query: 295 XRCQHSCVNTPGSYH------CTCREGWHLRADGRSCRDIDECAGGAR-----PCGGGQC 343
Q C S + C C G R G C ++ G A+ P G G
Sbjct: 2388 EVLQTICQMASSSRNLVTKSECCCDGG---RGWGHQC-ELCPLPGTAQYKKICPHGPGYT 2443
Query: 344 RNTVGSYTC-----TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQI 398
+ C CT+G + G+ + D IS + +DE +S
Sbjct: 2444 TDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTD-ISGTSCIDLDECSQS----- 2497
Query: 399 PELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
P+ C C NT GS+ C CP GY V E G C D DEC+ +C C+N G F
Sbjct: 2498 PKPCNY-ICKNTEGSYQCSCPRGY-VLQEDGKTCKDLDECQTKQHNCQFL--CVNTLGGF 2553
Query: 459 QCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C+C G+ C D +EC + C + C NT GSF C C G+ D GL
Sbjct: 2554 TCKCPPGFTQHHTACIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGL---- 2609
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C D+DEC + C++G C N GGY C C G+ + C+
Sbjct: 2610 ---NCEDVDECDGNHR-CQHG-CQNILGGYRCGCPQGYIQHYQWNQCV 2652
Score = 215 bits (525), Expect = 3e-55
Identities = 143/468 (30%), Positives = 200/468 (42%), Gaps = 55/468 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C+C GYE D+ C+D++EC + +C +G C
Sbjct: 767 DINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCR 826
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT GS++C C PGY ++ C DI+EC N C G C N GSF CEC G +L+
Sbjct: 827 NTPGSYSCTCPPGYVFRTETETCEDINECESNP--CVNGACRNNLGSFNCECSPGSKLSS 884
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
L C D G C + C+ +T+KS C
Sbjct: 885 TGLICID----------SLKGTC--WLNIQDSRCEVNINGATLKSE-CCATLGAAWGSPC 931
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+ ++T C G R G +C D++EC C G+C N+ GS+ C C +G
Sbjct: 932 ERCELDT------ACPRGL-ARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEG 984
Query: 358 LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPE---LCGAGSCHNT---- 410
L G C DI + + DE V + C G+ T
Sbjct: 985 LTLDGTGR--VCLDI----RMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEE 1038
Query: 411 -----IGSFVCQCPDGYSVKPEQG-----PACTDDDECELGTCDCHPAADCINLPGSFQC 460
+ CP G P D +EC+ C C N GSF+C
Sbjct: 1039 CPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMC-TYGKCRNTIGSFKC 1097
Query: 461 RCRDGWRGD--GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
RC G+ D C D+DEC + C C NT GSF C C GY+ G+ +
Sbjct: 1098 RCNSGFALDMEERNCTDIDECRISPDLC-GSGICVNTPGSFECECFEGYE-SGFMM---- 1151
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ +C+DID C +P LC G C NT G ++CDC +G + C+
Sbjct: 1152 -MKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCV 1198
Score = 201 bits (491), Expect = 5e-51
Identities = 148/494 (29%), Positives = 206/494 (41%), Gaps = 66/494 (13%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC LC +G CRN G ++C C PGY ++ TC D+NECE C +G C
Sbjct: 808 IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECE--SNPCVNGAC 865
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDI--DECADN--DALCR--------GGRCVNTAGS 224
N GSF C C PG K IC+D C N D+ C C T G+
Sbjct: 866 RNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGA 925
Query: 225 F------RCE----CGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
RCE C G+ ++C+D++EC + G+C NG C N G++ C C EG
Sbjct: 926 AWGSPCERCELDTACPRGLARIKG-VTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEG 984
Query: 275 YAQSTVKSHXXXXXXXXXXXXRCQHSCVN-TPGSYH---CTCREGWHLRADGRSC----- 325
+ C++ PG + C C G + C
Sbjct: 985 LTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGT 1044
Query: 326 RDIDE-CAGGARPCGGGQCR---------NTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
++ + C GA G N ++ CT G + G+ C+
Sbjct: 1045 KEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSF-KCRCNSGF 1103
Query: 376 ADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD 435
A + +DE + S P+LCG+G C NT GSF C+C +GY C D
Sbjct: 1104 ALDMEERNCTDIDECRIS-----PDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDI 1158
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCA 493
D CE C C+N GSFQC C G C D++EC ++ C C
Sbjct: 1159 DGCERNPLLCR-GGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCR-NGKCV 1216
Query: 494 NTDGSFRCLCDTGYKG--DGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
N G+++C C+ GY+ D G C DIDEC C+ C+N+ G YEC
Sbjct: 1217 NMIGTYQCSCNPGYQATPDRQG---------CTDIDECMIMNGGCDT-QCTNSEGSYECS 1266
Query: 552 CDVGFTRAADGRSC 565
C G+ DGRSC
Sbjct: 1267 CSEGYALMPDGRSC 1280
Score = 199 bits (486), Expect = 2e-50
Identities = 133/411 (32%), Positives = 178/411 (43%), Gaps = 47/411 (11%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
CR G+ + + C D+DEC +C+GG C+NT GSF C C G + + C+DID
Sbjct: 260 CRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDID 319
Query: 247 ECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS----HXXXXXXXXXXXXRCQHSCV 302
ECSI GIC G C N +G+Y CVC GY ST S RC
Sbjct: 320 ECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELP 379
Query: 303 NTPGSYHCTCREG--WHLRADGRSC--RDIDE----C-----------AGGARPCG-GGQ 342
C C G W + +C R +E C + G+RP G GG
Sbjct: 380 GRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGN 439
Query: 343 CRNTVGSYTCTCTDGL----VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVD--P 396
G+ G +P G P A II + L +++D
Sbjct: 440 GFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPII-TGLTILNQTIDICK 498
Query: 397 QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPG 456
LC G C T+ S+ C+C GY K + C D DEC C DC+N PG
Sbjct: 499 HHANLCLNGRCIPTVSSYRCECNMGY--KQDANGDCIDVDECTSNPC---TNGDCVNTPG 553
Query: 457 SFQCRCRDGWRGDGA--TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
S+ C+C G++ C D+DEC+ N C C N+DGSF+C+C+ G++ G
Sbjct: 554 SYYCKCHAGFQRTPTKQACIDIDECIQNGVLC-KNGRCVNSDGSFQCICNAGFELTTDG- 611
Query: 515 RTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+CVD DEC +C NG C N G ++C C GF A +GR C
Sbjct: 612 ------KNCVDHDECTT-TNMCLNGMCINEDGSFKCICKPGFVLAPNGRYC 655
Score = 199 bits (486), Expect = 2e-50
Identities = 144/460 (31%), Positives = 197/460 (42%), Gaps = 49/460 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD--VNECEIVDGVCGDGD 175
+++ECA P C +G C N G + C+C P ++ + CVD V C + G GDG
Sbjct: 1531 DIDECAD-PINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDG- 1588
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFR-CECGHGME 234
S +C+ G S C + + N C VN+ + C G G
Sbjct: 1589 ------SLSCNTEIGVGVSR-SSCCCSLGKAWGNP--CETCPPVNSTEYYTLCPGGEGFR 1639
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
P + +DIDEC G+C G C N G++QC C +GY S
Sbjct: 1640 PNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHP 1699
Query: 295 XRC-QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN----TVGS 349
C +C NT G+Y C C + G +C D+ + + R G C N V
Sbjct: 1700 GVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRK-SFCYRSYNGTTCENELPFNVTK 1758
Query: 350 YTCTCTDGL------------VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
C CT + P A K C +I I T + +DE + +
Sbjct: 1759 RMCCCTYNVGKAGNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECK-----E 1813
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
IP +C G C N IGSF C+CP G+S + C D DEC G C ADCIN PGS
Sbjct: 1814 IPGICANGVCINQIGSFRCECPTGFSYN-DLLLVCEDIDECSNGDNLCQRNADCINSPGS 1872
Query: 458 FQCRCRDGWR-GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
++C C G++ C D +ECL C C + GS++C+C G+K +T
Sbjct: 1873 YRCECAAGFKLSPNGACVDRNECLEIPNVC-SHGLCVDLQGSYQCICHNGFKASQD--QT 1929
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
+ C+D+DEC P C NG C NT G Y C C GF
Sbjct: 1930 M-----CMDVDECERHP--CGNGTCKNTVGSYNCLCYPGF 1962
Score = 194 bits (473), Expect = 7e-49
Identities = 148/472 (31%), Positives = 206/472 (43%), Gaps = 52/472 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGV-CGDGDC 176
+++EC+ F +C G C NL G F C C GYE D C D++EC D + C +G C
Sbjct: 1490 DIDECS-FQNICVSGTCNNLPGMFHCICDDGYELDRTGGNCTDIDEC--ADPINCVNGLC 1546
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT G + C+C P ++ + CVD N L G R GS C G+ ++
Sbjct: 1547 VNTPGRYECNCPPDFQLNPTGVGCVD--NRVGNCYLKFGPR---GDGSLSCNTEIGVGVS 1601
Query: 237 PDRLSCKDIDECSITSGICSNGACEN----QMGTYQCVCD--EGYAQSTVKSHXXXXXXX 290
R SC CS+ G CE Y +C EG+ + +
Sbjct: 1602 --RSSCC----CSL--GKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDEC 1653
Query: 291 XXXXXRCQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
CQ +C+NT GS+ C C +G++L D R C DIDEC CG G C NT+G+
Sbjct: 1654 QELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGN 1713
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC--GAGSC 407
YTC C + G C D+ + S +EL +V ++ C G
Sbjct: 1714 YTCICPPEYMQVNGGHN--CMDMRKSFCYRSYNGTTCENELPFNVTKRMC-CCTYNVGKA 1770
Query: 408 HN-------TIGSF----VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPG 456
N T G+ +C G++ G A D DEC+ C CIN G
Sbjct: 1771 GNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKA-VDIDECKEIPGICANGV-CINQIG 1828
Query: 457 SFQCRCRDGWRGDGA--TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
SF+C C G+ + CED+DEC + C A C N+ GS+RC C G+K G
Sbjct: 1829 SFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG- 1887
Query: 515 RTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+CVD +EC P +C +G C + G Y+C C GF + D C+
Sbjct: 1888 -------ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCM 1932
Score = 193 bits (471), Expect = 1e-48
Identities = 128/394 (32%), Positives = 172/394 (43%), Gaps = 69/394 (17%)
Query: 203 IDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACEN 262
ID C + LC GRC+ T S+RCEC G + + C D+DEC TS C+NG C N
Sbjct: 494 IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANG-DCIDVDEC--TSNPCTNGDCVN 550
Query: 263 QMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRAD 321
G+Y C C G+ ++ K C++ CVN+ GS+ C C G+ L D
Sbjct: 551 TPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELTTD 610
Query: 322 GRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLIST 381
G++C D DEC C G C N GS+ C C G V + G C D+DEC
Sbjct: 611 GKNCVDHDECTT-TNMCLNGMCINEDGSFKCICKPGFVLAPNGRY--CTDVDEC------ 661
Query: 382 IIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
Q P +C G C N+ GSF C CP G +V + G C D
Sbjct: 662 ---------------QTPGICMNGHCINSEGSFRCDCPPGLAVGMD-GRVCVDTHM--RS 703
Query: 442 TC-DCHPAADCIN-LPGSF---QCRCRDGWRGDGATCE---------------------- 474
TC C+ PG+ +C C + G G C+
Sbjct: 704 TCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITV 763
Query: 475 ---DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
D++EC + C C N GS+RC C++GY+ D G +C+DIDEC
Sbjct: 764 DGRDINECALDPDIC-ANGICENLRGSYRCNCNSGYEPDASGR-------NCIDIDECLV 815
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+ LC+NG C NTPG Y C C G+ + +C
Sbjct: 816 NRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETC 849
Score = 173 bits (420), Expect = 2e-42
Identities = 88/242 (36%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC+ P C + C+N G + C C GY TC D++EC+ C C
Sbjct: 2489 IDLDECSQSPKPCNY-ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNC-QFLC 2546
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G FTC C PG+ + C+D +EC LC G G C NT GSF CEC G L
Sbjct: 2547 VNTLGGFTCKCPPGFTQHHTA--CIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSL 2604
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
L+C+D+DEC + C +G C+N +G Y+C C +GY Q +
Sbjct: 2605 DATGLNCEDVDECD-GNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA 2662
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
SC NT GSY C C G+ +C D++EC+ PC G C NT G Y C C
Sbjct: 2663 CGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCP 2721
Query: 356 DG 357
G
Sbjct: 2722 PG 2723
Score = 160 bits (389), Expect = 1e-38
Identities = 116/345 (33%), Positives = 148/345 (42%), Gaps = 53/345 (15%)
Query: 245 IDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS-CVN 303
ID C + +C NG C + +Y+C C+ GY Q ++ C + CVN
Sbjct: 494 IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQD---ANGDCIDVDECTSNPCTNGDCVN 550
Query: 304 TPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAA 363
TPGSY+C C G+ ++C DIDEC C G+C N+ GS+ C C G +
Sbjct: 551 TPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELTTD 610
Query: 364 GAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYS 423
G C D DEC +C G C N GSF C C G+
Sbjct: 611 GKN--CVDHDECTTT---------------------NMCLNGMCINEDGSFKCICKPGFV 647
Query: 424 VKPEQGPACTDDDECEL-GTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECL 480
+ P G CTD DEC+ G C CIN GSF+C C G DG C D
Sbjct: 648 LAPN-GRYCTDVDECQTPGIC---MNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 703
Query: 481 TNNGG-----C---HPRAT------CANTDGSFR--CL-CDTGYKGDGYGLRT--VCCVY 521
T GG C P A CAN D F C C + +GL + V
Sbjct: 704 TCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITV 763
Query: 522 SCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
DI+ECA DP +C NG C N G Y C+C+ G+ A GR+C+
Sbjct: 764 DGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCI 808
Score = 102 bits (245), Expect = 3e-21
Identities = 49/134 (36%), Positives = 68/134 (50%), Gaps = 5/134 (3%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
C G+ + + C DV+EC+ + G+C G+C NT GSF C C G+K + ++ C DID
Sbjct: 260 CRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDID 319
Query: 205 ECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ- 263
EC+ +C G C NT GS+ C C G + D C D SG+ NG C +
Sbjct: 320 ECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLV-NGRCAQEL 378
Query: 264 ---MGTYQCVCDEG 274
M QC C+ G
Sbjct: 379 PGRMTKMQCCCEPG 392
Score = 91.1 bits (216), Expect = 1e-17
Identities = 79/260 (30%), Positives = 102/260 (39%), Gaps = 34/260 (13%)
Query: 310 CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTC 369
CTC G G + I +C+ R GG C + C C G + + G +P C
Sbjct: 130 CTCSSGQISSTCGS--KSIQQCS--VRCMNGGTCADD----HCQCQKGYIGTYCG-QPVC 180
Query: 370 QDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQG 429
++ C + I + PQ G C + + +CQ G G
Sbjct: 181 EN--GCQNG-GRCIAQPCACVYGFTGPQCERDYRTGPCFTQVNNQMCQ---GQLT----G 230
Query: 430 PACTDDDECEL-GTCDCHPAADCINLPGSFQCRCRDGWRGDGAT--CEDVDECLTNNGGC 486
CT C G HP C P CR G+ + T C+DVDEC G C
Sbjct: 231 IVCTKTLCCATTGRAWGHPCEMCPAQPQP----CRRGFIPNIRTGACQDVDECQAIPGIC 286
Query: 487 HPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG 546
C NT GSF C C G+K C DIDEC+ P +CE G CSNT G
Sbjct: 287 QG-GNCINTVGSFECRCPAGHKQSE-------TTQKCEDIDECSIIPGICETGECSNTVG 338
Query: 547 GYECDCDVGFTRAADGRSCL 566
Y C C G+ + DG C+
Sbjct: 339 SYFCVCPRGYVTSTDGSRCI 358
Score = 89.8 bits (213), Expect = 2e-17
Identities = 34/85 (40%), Positives = 48/85 (56%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC A PG+C G C N +G F C C G+++ C D++EC I+ G+C G+C
Sbjct: 275 DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECS 334
Query: 178 NTEGSFTCHCRPGYKADDFSKICVD 202
NT GS+ C C GY C+D
Sbjct: 335 NTVGSYFCVCPRGYVTSTDGSRCID 359
Score = 71.7 bits (168), Expect = 6e-12
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++ NEC+ P CG C N LG + C C G+ D + C DVNEC C G C
Sbjct: 2652 VDENECSN-PNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-C 2709
Query: 177 HNTEGSFTCHCRPGY 191
NTEG + C C PGY
Sbjct: 2710 SNTEGGYLCGCPPGY 2724
Score = 50.0 bits (114), Expect = 2e-05
Identities = 21/47 (44%), Positives = 30/47 (63%), Gaps = 2/47 (4%)
Query: 3 GGRCSGPLPTDVLRAVCCCSA-LGKAWGNQRCEPCPKKGTDAYQNLC 48
G C LP +V + +CCC+ +GKA GN+ CEPCP GT ++ +C
Sbjct: 1745 GTTCENELPFNVTKRMCCCTYNVGKA-GNKPCEPCPTPGTADFKTIC 1790
Score = 49.6 bits (113), Expect = 3e-05
Identities = 21/43 (48%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C P+P CCC A+G AWG + CE CPK GT Y+ LC
Sbjct: 1011 CIHPVPGKFRMDACCC-AVGAAWGTE-CEECPKPGTKEYETLC 1051
Score = 48.4 bits (110), Expect = 7e-05
Identities = 21/46 (45%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Query: 4 GRCSGPLPTDVLRAVCCCSAL-GKAWGNQRCEPCPKKGTDAYQNLC 48
G+CS P + +A CCCS + G+ WG+ CE CPK A+Q+LC
Sbjct: 2110 GKCSVPKAFNTTKAKCCCSKMPGEGWGDP-CELCPKDDEVAFQDLC 2154
Score = 40.7 bits (91), Expect = 0.013
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V ++ CCC G+ WG+Q CE CP GT Y+ +C
Sbjct: 2404 VTKSECCCDG-GRGWGHQ-CELCPLPGTAQYKKIC 2436
Score = 34.7 bits (76), Expect = 0.89
Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 1/32 (3%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCP 37
C G L V CC+ G+AWG+ CE CP
Sbjct: 224 CQGQLTGIVCTKTLCCATTGRAWGHP-CEMCP 254
>AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.
Length = 2816
Score = 437 bits (1076), Expect = e-122
Identities = 196/449 (43%), Positives = 252/449 (56%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC FPGLC HG CRN +G F C C G+ D++ C D++EC I +CG G C
Sbjct: 993 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1052
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY++ K C+D+DECA + LCRGG C NT GS++C+C G EL
Sbjct: 1053 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1112
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+C+DIDECS++ G+C +G C N +G +QC C G+ + +
Sbjct: 1113 AKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGG 1172
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C C+NT GSY C+C +G+ L DGR+C D+DEC R C G C N G + C C D
Sbjct: 1173 CDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYD 1232
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A TC D+DEC DL P +C G C NT GSFVC
Sbjct: 1233 GFM--ATPDMRTCVDVDEC-DL-------------------NPHICLHGDCENTKGSFVC 1270
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GY V+ + C+D DECE+G +C A C+N+PGSF CRC GW GDG C D+
Sbjct: 1271 HCQLGYMVR-KGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDL 1329
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC++ C PR C N GS+RC C G+ GDG + C D DECA + LC
Sbjct: 1330 DECISQEHRCSPRGDCLNVPGSYRCTCRQGFAGDG---------FFCEDRDECAENVDLC 1380
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+NG C N PGGY C+C++GF D R+C
Sbjct: 1381 DNGQCLNAPGGYRCECEMGFDPTEDHRAC 1409
Score = 299 bits (734), Expect = 2e-80
Identities = 164/454 (36%), Positives = 216/454 (47%), Gaps = 42/454 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+V+ECA P LC G C N G + C C PG+E +K C D++EC + DG+C G C
Sbjct: 1077 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQC 1136
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G+F C C G+++ + CVDI+EC + C C+NT GS+RC CG G L
Sbjct: 1137 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC-DVHCINTEGSYRCSCGQGYSLM 1195
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
PD +C D+DEC +C G C N G ++C+C +G+ +
Sbjct: 1196 PDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHI 1255
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTC 354
C H C NT GS+ C C+ G+ +R C D+DEC G C C N GS++C C
Sbjct: 1256 CLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRC 1315
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G V G C D+DEC IS + P+ G C N GS+
Sbjct: 1316 LPGWV----GDGFECHDLDEC---ISQ---------EHRCSPR-------GDCLNVPGSY 1352
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C C G++ G C D DEC D C+N PG ++C C G+ D
Sbjct: 1353 RCTCRQGFA---GDGFFCEDRDEC-AENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRA 1408
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C+DVDEC G +C N G FRC+C+ GY+ D G +C DI+ECA D
Sbjct: 1409 CQDVDECA--QGNLCAFGSCENLPGMFRCICNGGYELDRGG-------GNCTDINECA-D 1458
Query: 533 PTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P C NG C NTPG Y C C F G C+
Sbjct: 1459 PVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1492
Score = 261 bits (640), Expect = 4e-69
Identities = 182/571 (31%), Positives = 249/571 (43%), Gaps = 70/571 (12%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
+G CS + V RA CCCS LG+AWGN CE CP T Y+ LC G PN+
Sbjct: 1509 SGISCSAEIGVGVTRASCCCS-LGRAWGNP-CELCPMANTTEYRTLCPG-GEGFQPNR-- 1563
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNE 121
+T I + DE + G G + +++E
Sbjct: 1564 ------ITVILEDI--DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDE 1615
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C-EIVDGVCGDGDCHN 178
C+ G+CG G C N LG +TC C Y + + + C+D+ + C +G C + N
Sbjct: 1616 CSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFN 1675
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
C C +++ C + C + C N A F + G L
Sbjct: 1676 VTRKMCC-CSYNI-GQAWNRPC---EACPTPISPDYQILCGNQAPGFLTDIHTGKPL--- 1727
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
DIDEC IC+NG C NQ+G+++C C G+ +++ CQ
Sbjct: 1728 -----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1782
Query: 299 HS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
+ C+N PGSY C C G+ L + G +C +EC C G C +T GSY C C
Sbjct: 1783 QNADCINIPGSYRCKCTRGYKL-SPGGACVGQNECREIPNVCSHGDCMDTEGSYMCLCHR 1841
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G SA + C DIDEC D Q P CG G+C N IGS+ C
Sbjct: 1842 GFQASAD--QTLCMDIDEC-------------------DRQ-P--CGNGTCKNIIGSYNC 1877
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCE 474
C G+ V C D DEC C+N GSF C C+DG+ DG C
Sbjct: 1878 LCFPGFVVT--HNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCV 1935
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D +ECL+ G C P TC N +GSFRC+C G++ C+DIDEC+ +P
Sbjct: 1936 DTNECLSLAGTCLP-GTCQNLEGSFRCICPPGFQVQSD---------HCIDIDECSEEPN 1985
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
LC G C+N+PG ++C C GF + +G C
Sbjct: 1986 LCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2016
Score = 258 bits (633), Expect = 3e-68
Identities = 163/475 (34%), Positives = 220/475 (46%), Gaps = 73/475 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGD 175
++++EC P +C +G C N +G F C+C G+ +S C DV+EC + C + D
Sbjct: 1727 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1786
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C GYK CV +EC + +C G C++T GS+ C C G +
Sbjct: 1787 CINIPGSYRCKCTRGYKLSP-GGACVGQNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1845
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D+ C DIDEC C NG C+N +G+Y C+C G+ +
Sbjct: 1846 SADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1903
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+ C+NT GS+HC C++G+ L ADG++C D +EC A C G C+N GS+ C C
Sbjct: 1904 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCIC 1963
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + C DIDEC+ + P LC G+C N+ GSF
Sbjct: 1964 PPGFQVQS----DHCIDIDECS--------------------EEPNLCLFGTCTNSPGSF 1999
Query: 415 VCQCPDGYSVKPEQGPACTDDDE--C----ELGTCDCHPAAD-------CINLPG----- 456
C CP G+ V + G C D + C E G C A + C PG
Sbjct: 2000 QCLCPPGF-VLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGD 2058
Query: 457 -----------SFQCRCRDGW---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+FQ C G G + EDV+EC N G C C NTDGSFRC
Sbjct: 2059 PCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVC-TNGVCVNTDGSFRCE 2117
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECA-NDPTLCENGHCSNTPGGYECDCDVGF 556
C GY D G+ +CVD DEC+ P C G C+N GG+EC C GF
Sbjct: 2118 CPFGYSLDFTGI-------NCVDTDECSVGHP--CGQGTCTNVIGGFECACADGF 2163
Score = 258 bits (631), Expect = 5e-68
Identities = 169/524 (32%), Positives = 227/524 (43%), Gaps = 36/524 (6%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRC-EPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
GGRC+G L R CCC G+ W E CP +G++ +Q LC LLP +
Sbjct: 308 GGRCAGDLAGHYTRRQCCCDR-GRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGL 366
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGE-NXXXXXXXXXXXXXXXXXXXXXXXXQMEVN 120
P +G NG G N ++
Sbjct: 367 FP---------GLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTID 417
Query: 121 ECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTE 180
C F LC +GRC + C+C GY +D + C+DV+EC C GDC N
Sbjct: 418 ICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDEC--TSSPCHHGDCVNIP 474
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
G++ C C PG++A + CVD+DEC + LC GRCVNT GSF+C C G EL+PD
Sbjct: 475 GTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGK 534
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+C D +EC+ TS +C NG C N+ G++ C+C G+ + +
Sbjct: 535 NCVDHNECA-TSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH 593
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCR----NTVGSYTCTCTD 356
C NT GS+ C C G + DGR C D + G C TV C C +
Sbjct: 594 CTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCAN 653
Query: 357 GLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
P +P CQ + E L S+ + ++ D + PE+C G C N
Sbjct: 654 ---PDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR 709
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GD 469
GS+ C C GY G CTD DEC L + C C N PGS+ C C G+ D
Sbjct: 710 GSYRCVCNLGYEA-GASGKDCTDVDECALNSLLCDNGW-CQNSPGSYSCSCPPGFHFWQD 767
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
C+DVDECL++ C C N GS+ C C G + D G
Sbjct: 768 TEICKDVDECLSS--PC-VSGVCRNLAGSYTCKCGPGSRLDPSG 808
Score = 250 bits (611), Expect = 1e-65
Identities = 155/466 (33%), Positives = 207/466 (44%), Gaps = 32/466 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC P +C G C N+ GG C C+ G+ TCVDV+EC++ +C GDC
Sbjct: 1203 DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCE 1262
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC+ GY + C D+DEC C C+N GSF C C G
Sbjct: 1263 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--V 1320
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D C D+DEC CS G C N G+Y+C C +G+A
Sbjct: 1321 GDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL- 1379
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C + C+N PG Y C C G+ D R+C+D+DECA G C G C N G + C C
Sbjct: 1380 -CDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQG-NLCAFGSCENLPGMFRCIC 1437
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTI--IMMSVDELQKSVDPQIPEL--CGAGSCHNT 410
G G C DI+ECAD ++ I + ++ PQ EL G G
Sbjct: 1438 NGGYELDRGGG--NCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTR 1495
Query: 411 IGSFVCQCPD----GYSVKPEQGPACTDDD-ECELGTCDCHPAADC-INLPGSFQCRC-- 462
G+ + D G S E G T C LG +P C + ++ C
Sbjct: 1496 AGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPG 1555
Query: 463 RDGWRGDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
+G++ + T ED+DEC G C C NT GSF+C C GY +
Sbjct: 1556 GEGFQPNRITVILEDIDECQELPGLCQ-GGDCVNTFGSFQCECPPGYHLSEH-------T 1607
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DIDEC+ +C G C NT G Y C C + + G +C+
Sbjct: 1608 RICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCM 1653
Score = 247 bits (604), Expect = 9e-65
Identities = 156/461 (33%), Positives = 199/461 (43%), Gaps = 31/461 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNECA PG+C +G C N G F C+C GY D CVD +EC V CG G C
Sbjct: 2091 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCT 2149
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G F C C G++ C DIDEC+ N LC RC NT GS+ C C G L
Sbjct: 2150 NVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLC-AFRCHNTEGSYLCTCPAGYTLRE 2207
Query: 238 DRLSCKDIDECSITSGIC-SNG-ACENQMGTYQCVCDEGYAQSTVKSHX-XXXXXXXXXX 294
D C+D+DEC+ C + G C+N +GT+ CVC G
Sbjct: 2208 DGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQP 2267
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN-TVGSYTC 352
C + CVNT GS+ C C EG+ C DI + A CR+ + S
Sbjct: 2268 DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVL-QTMCRSLSSSSEAV 2326
Query: 353 TCTDGLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
T + G P C+ L + + + LC G C
Sbjct: 2327 TRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGEC 2386
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW- 466
N++GSF C C GY+ C D DEC C C N GSF C C G+
Sbjct: 2387 INSLGSFRCHCQAGYT-PDATATTCLDMDECSQVPKPC--TFLCKNTKGSFLCSCPRGYL 2443
Query: 467 -RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
DG TC+D+DEC + C + C NT G+F C C G+ +C D
Sbjct: 2444 LEEDGRTCKDLDECTSRQHNC--QFLCVNTVGAFTCRCPPGFTQHH---------QACFD 2492
Query: 526 IDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DEC+ P C +GHC NTPG + C+C GFT + G C
Sbjct: 2493 NDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGC 2533
Score = 243 bits (594), Expect = 2e-63
Identities = 157/448 (35%), Positives = 205/448 (45%), Gaps = 74/448 (16%)
Query: 157 TCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI-----------DE 205
TC DVNECE GVC +G C NT GSF C C G D ++CVD+ DE
Sbjct: 873 TCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDE 932
Query: 206 CADN-DALCRGGRCVNTAGSF---RCE-------------CGHGMELAP-DRLS----CK 243
C R C + G+ CE C G+ A D LS K
Sbjct: 933 CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYK 992
Query: 244 DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHSCV 302
D++EC + G+C++G C N +G++ C C G+A + + C Q +CV
Sbjct: 993 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1052
Query: 303 NTPGSYHCTCREGWHLR-ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
NTPGS+ C C G+ ++C D+DECA C GG C NT GSY C C G +
Sbjct: 1053 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1112
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
A G C+DIDEC S+ + LC G C N IG+F C C G
Sbjct: 1113 AKGT--ACEDIDEC----------SLSD----------GLCPHGQCVNVIGAFQCSCHAG 1150
Query: 422 YSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVD 477
+ P++ C D +EC + G CD H CIN GS++C C G+ DG C DVD
Sbjct: 1151 FQSTPDR-QGCVDINECRVQNGGCDVH----CINTEGSYRCSCGQGYSLMPDGRACADVD 1205
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC N C + C N G RCLC G+ +RT CVD+DEC +P +C
Sbjct: 1206 ECEENPRVC-DQGHCTNMPGGHRCLCYDGFMATP-DMRT------CVDVDECDLNPHICL 1257
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
+G C NT G + C C +G+ C
Sbjct: 1258 HGDCENTKGSFVCHCQLGYMVRKGATGC 1285
Score = 239 bits (586), Expect = 1e-62
Identities = 169/500 (33%), Positives = 218/500 (43%), Gaps = 87/500 (17%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC + P C HG C N+ G + C C+PG++ CVDV+EC + G+C G C
Sbjct: 455 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 512
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NTEGSF C C G++ K CVD +ECA + +C G C+N GSF C C G LA
Sbjct: 513 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATS-TMCVNGVCLNEDGSFSCLCKPGFLLA 571
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTY--QC-----------VCDEGYAQST---- 279
P C DIDEC T GIC NG C N G++ QC VC + + +ST
Sbjct: 572 PGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 630
Query: 280 --------------VKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
KS CQ + C G + DGR
Sbjct: 631 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 688
Query: 326 RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
DI+ECA C G C N GSY C C G A+G C D+DECA
Sbjct: 689 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKD--CTDVDECA--------- 736
Query: 386 SVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
++ L LC G C N+ GS+ C CP G+ + C D DEC C
Sbjct: 737 -LNSL----------LCDNGWCQNSPGSYSCSCPPGFHFWQDT-EICKDVDECLSSPC-- 782
Query: 446 HPAADCINLPGSFQCRCRDGWRGD--GATCED---------VDE--CLTNNGGCHPRATC 492
+ C NL GS+ C+C G R D G C D + E C N G R+ C
Sbjct: 783 -VSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSEC 841
Query: 493 ANTDGSF------RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG 546
T G+ RC D G+ T +C D++EC + P +C NG C NT G
Sbjct: 842 CATLGAAWGSPCERCEIDPAC-ARGFARMTGV---TCDDVNECESFPGVCPNGRCVNTAG 897
Query: 547 GYECDCDVGFTRAADGRSCL 566
+ C+C G A GR C+
Sbjct: 898 SFRCECPEGLMLDASGRLCV 917
Score = 239 bits (584), Expect = 2e-62
Identities = 154/457 (33%), Positives = 206/457 (45%), Gaps = 63/457 (13%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG-D 175
+++EC+ P LC RC N G + C C GY C DV+EC C G +
Sbjct: 2173 DIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGME 2231
Query: 176 CHNTEGSFTCHCRPGYKADDFS-KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C N G+F C C PG + S + C D +EC LC GRCVNTAGSFRC+C G +
Sbjct: 2232 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2291
Query: 235 LAPDRLSCKDIDE----CSITSGICSNGACENQMGTY-QCVCDEGYAQSTVKSHXXXXXX 289
+P C DI + + +C + + ++ T +C C G
Sbjct: 2292 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGP---------- 2341
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
RC+ + +Y C G A+GR D+DEC A C G+C N++GS
Sbjct: 2342 ------RCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLCAHGECINSLGS 2392
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
+ C C G P A TC D+DEC+ Q+P+ C C N
Sbjct: 2393 FRCHCQAGYTPDATAT--TCLDMDECS--------------------QVPKPC-TFLCKN 2429
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
T GSF+C CP GY ++ E G C D DEC +C C+N G+F CRC G+
Sbjct: 2430 TKGSFLCSCPRGYLLE-EDGRTCKDLDECTSRQHNCQFL--CVNTVGAFTCRCPPGFTQH 2486
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
C D DEC G C C NT GSFRC C G+ V + C D++EC
Sbjct: 2487 HQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGF-------TLVSSGHGCEDVNEC 2539
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ P C++G C N GGY C C GFT+ + C+
Sbjct: 2540 -DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCV 2574
Score = 231 bits (564), Expect = 7e-60
Identities = 159/484 (32%), Positives = 212/484 (43%), Gaps = 73/484 (15%)
Query: 118 EVNECAAFPGLCGHGR---CRNLLGGFTCDCFPGYEK-DSKNHTCVDVNECEIVDGVCGD 173
+V+ECA C H R C+NL+G F C C PG C D NEC +C +
Sbjct: 2214 DVDECADGQQDC-HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVN 2272
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDE--CADN--DALCRGGRCVNTAGS-FRCE 228
G C NT GSF C C G++ C DI + C +CR + A + C
Sbjct: 2273 GRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECC 2332
Query: 229 CGHGM------ELAP------DRLSC----------KDIDECSITSGICSNGACENQMGT 266
CG G EL P R C +D+DEC + + +C++G C N +G+
Sbjct: 2333 CGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGS 2392
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR 326
++C C GY + C C NT GS+ C+C G+ L DGR+C+
Sbjct: 2393 FRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2452
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
D+DEC C C NTVG++TC C G C D DEC+
Sbjct: 2453 DLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFTQH----HQACFDNDECSAQ-------- 2499
Query: 387 VDELQKSVDPQIPELCGA-GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
P CGA G CHNT GSF C+C G+++ G C D +EC+ G C
Sbjct: 2500 ------------PGPCGAHGHCHNTPGSFRCECHQGFTLV-SSGHGCEDVNECD-GPHRC 2545
Query: 446 HPAADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N G ++C C G+ A C D +EC + C A+C NT G FRC+C
Sbjct: 2546 QHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGS-ASCRNTLGGFRCVC 2602
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGR 563
+G+ D + C D+DECA C C+NTPGG+ C C G+ RA G
Sbjct: 2603 PSGFDFDQ-------ALGGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQGH 2654
Query: 564 SCLG 567
G
Sbjct: 2655 CVSG 2658
Score = 230 bits (563), Expect = 9e-60
Identities = 151/465 (32%), Positives = 209/465 (44%), Gaps = 52/465 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C C GYE + C DV+EC + +C +G C
Sbjct: 689 DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQ 748
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N+ GS++C C PG+ ++IC D+DEC + C G C N AGS+ C+CG G L P
Sbjct: 749 NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDP 806
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
C D T G C E++ C+ ++++S C
Sbjct: 807 SGTFCLD-----STKGTCWLKIQESR-------CEVNLQGASLRSE-CCATLGAAWGSPC 853
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+ C P C G+ R G +C D++EC C G+C NT GS+ C C +G
Sbjct: 854 ER-CEIDP-----ACARGF-ARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEG 906
Query: 358 LVPSAAGAKPTCQDI-----------DECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
L+ A+G C D+ DEC + M D S+ C A
Sbjct: 907 LMLDASGR--LCVDVRLEPCFLRWDEDECGVTLPGKYRM--DVCCCSIGAVWGVECEACP 962
Query: 407 CHNTIGSFVCQCPDGYSVKPEQ----GPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
++ F CP G P D +EC++ C C N GSF C C
Sbjct: 963 DPESL-EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCAC 1020
Query: 463 RDGWRGDG--ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ D C D+DEC + C + TC NT GSF C C GY+ G+ L +
Sbjct: 1021 AGGFALDAQERNCTDIDECRISPDLC-GQGTCVNTPGSFECECFPGYE-SGFML-----M 1073
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+C+D+DECA DP LC G C+NT G Y+C C G A G +C
Sbjct: 1074 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC 1118
Score = 230 bits (562), Expect = 1e-59
Identities = 165/510 (32%), Positives = 215/510 (42%), Gaps = 94/510 (18%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C--EIVDGVCG 172
++++EC+ P LC G C N G F C C PG+ H C D + C G C
Sbjct: 1975 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCS 2034
Query: 173 DGDCHN-TEGSFTCHCRPGYKADD------------FSKIC--------------VDIDE 205
N T+ C RPG D F ++C D++E
Sbjct: 2035 VPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNE 2094
Query: 206 CADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMG 265
CA+N +C G CVNT GSFRCEC G L ++C D DECS+ C G C N +G
Sbjct: 2095 CAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-GHPCGQGTCTNVIG 2153
Query: 266 TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
++C C +G+ + + C C NT GSY CTC G+ LR DG C
Sbjct: 2154 GFECACADGFEPGLMMT-CEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMC 2212
Query: 326 RDIDECAGGARPC--GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
RD+DECA G + C G +C+N +G++ C C G+ P G+ C D +EC
Sbjct: 2213 RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRP-LPGSGEGCTDDNEC-------- 2263
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKP--------EQGPA---- 431
Q P+LC G C NT GSF C C +G+ P QGP
Sbjct: 2264 -----HAQ-------PDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2311
Query: 432 ----C----TDDDECELGTCDC------HPAADCINLPGSFQCR--CRDGWRGDGATCED 475
C + + C C P + LPG+ R C G G A D
Sbjct: 2312 LQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG-SGYTAEGRD 2370
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
VDEC C C N+ GSFRC C GY D +C+D+DEC+ P
Sbjct: 2371 VDECRMLAHLC-AHGECINSLGSFRCHCQAGYTPD-------ATATTCLDMDECSQVPKP 2422
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C NT G + C C G+ DGR+C
Sbjct: 2423 C-TFLCKNTKGSFLCSCPRGYLLEEDGRTC 2451
Score = 195 bits (476), Expect = 3e-49
Identities = 135/431 (31%), Positives = 182/431 (42%), Gaps = 60/431 (13%)
Query: 147 PGYEKDSKNHTCV---DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
PG E N V D++EC+ + G+C GDC NT GSF C C PGY + ++IC DI
Sbjct: 1554 PGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDI 1613
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC+ + +C G C NT G++ C C +C D+ + NG C+N+
Sbjct: 1614 DECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNE 1671
Query: 264 MG----TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
+ C C Q+ + Q C N + G L
Sbjct: 1672 LAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDY---QILCGNQAPGFLTDIHTGKPL- 1727
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
DIDEC C G C N +GS+ C C G + C+D+DEC
Sbjct: 1728 -------DIDECGEIPAICANGICINQIGSFRCECPAGF--NYNSILLACEDVDECGSRE 1778
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC- 438
S Q++ D C N GS+ C+C GY + P G AC +EC
Sbjct: 1779 SPC--------QQNAD-----------CINIPGSYRCKCTRGYKLSP--GGACVGQNECR 1817
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTD 496
E+ H DC++ GS+ C C G++ D C D+DEC G TC N
Sbjct: 1818 EIPNVCSH--GDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG---NGTCKNII 1872
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN-DPTLCENGHCSNTPGGYECDCDVG 555
GS+ CLC G+ G CVD DEC +C GHC NT G + C C G
Sbjct: 1873 GSYNCLCFPGFVVTHNG--------DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDG 1924
Query: 556 FTRAADGRSCL 566
F ADG++C+
Sbjct: 1925 FELTADGKNCV 1935
Score = 168 bits (408), Expect = 5e-41
Identities = 88/250 (35%), Positives = 118/250 (47%), Gaps = 9/250 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC+ P C C+N G F C C GY + TC D++EC C C
Sbjct: 2411 LDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC-QFLC 2468
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G+FTC C PG+ + C D DEC+ C G C NT GSFRCEC G L
Sbjct: 2469 VNTVGAFTCRCPPGFT--QHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTL 2526
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
C+D++EC C +G C+NQ+G Y+C C +G+ Q + +
Sbjct: 2527 VSSGHGCEDVNECDGPHR-CQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPP 2584
Query: 296 RC-QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C SC NT G + C C G+ C+D+DECAG PC C NT G + C C
Sbjct: 2585 TCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPC-SYSCANTPGGFLCGC 2643
Query: 355 TDGLVPSAAG 364
G + G
Sbjct: 2644 PQGYFRAGQG 2653
Score = 136 bits (329), Expect = 2e-31
Identities = 122/399 (30%), Positives = 155/399 (38%), Gaps = 60/399 (15%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD--VNEC--EIVDGVC-G 172
+V+EC A PGLC G C N++G F C C G+ + C D C + G C G
Sbjct: 254 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAG 313
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDE------CADNDALCRGGRCVNTAGSFR 226
D H T C + A ++C CA L G +
Sbjct: 314 DLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGF 373
Query: 227 CECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
G G L P RL+ D GI S G + +GT A
Sbjct: 374 GSNGMGPPLGPARLNPHGSD----ARGIPSLGPGNSNIGT---------ATLNQTIDICR 420
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT 346
RC + TP SY C C G+ G C D+DEC + PC G C N
Sbjct: 421 HFTNLCLNGRC----LPTPSSYRCECNVGYTQDVRG-ECIDVDECT--SSPCHHGDCVNI 473
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
G+Y C C G A + C D+DEC ++S LC G
Sbjct: 474 PGTYHCRCYPGF--QATPTRQACVDVDEC--IVS------------------GGLCHLGR 511
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C NT GSF C C G+ + P+ G C D +EC T + C+N GSF C C+ G+
Sbjct: 512 CVNTEGSFQCVCNAGFELSPD-GKNCVDHNECATSTMCVNGV--CLNEDGSFSCLCKPGF 568
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
G C D+DEC T G C NT+GSFRC C
Sbjct: 569 LLAPGGHYCMDIDECQT--PGICVNGHCTNTEGSFRCQC 605
Score = 134 bits (324), Expect = 8e-31
Identities = 86/241 (35%), Positives = 105/241 (43%), Gaps = 39/241 (16%)
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
ID C C G+C T SY C C G G C D+DEC
Sbjct: 416 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE---CIDVDECTS---------- 462
Query: 388 DELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
P C G C N G++ C+C G+ P + AC D DEC + CH
Sbjct: 463 -------SP-----CHHGDCVNIPGTYHCRCYPGFQATPTR-QACVDVDECIVSGGLCH- 508
Query: 448 AADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
C+N GSFQC C G+ DG C D +EC T+ C C N DGSF CLC
Sbjct: 509 LGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM-C-VNGVCLNEDGSFSCLCKP 566
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G+ G + C+DIDEC P +C NGHC+NT G + C C G DGR C
Sbjct: 567 GFLLAPGG-------HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC 618
Query: 566 L 566
+
Sbjct: 619 V 619
Score = 82.6 bits (195), Expect = 3e-15
Identities = 117/458 (25%), Positives = 154/458 (33%), Gaps = 54/458 (11%)
Query: 136 NLLGG-FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKAD 194
N+ G F C PG+ CV I CG+G C C C G A
Sbjct: 65 NVCGSRFHAYCCPGWRTFPGRSQCV----VPICRRACGEGFCSQPN---LCTCADGTLAP 117
Query: 195 D--FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM--ELAPDRLSCKDIDECSI 250
S+ C N CRG C+ G CG + + C + C+
Sbjct: 118 SCGVSRGSGCSVSCM-NGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCAC 176
Query: 251 TSGICSNGACENQMGTYQC---VCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
G CE T C V EG C P
Sbjct: 177 VYGFMGP-QCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQ 235
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSAAGA 365
H CR G+ +C+D+DEC C GG C N VGS+ C C G L S+A
Sbjct: 236 PH-PCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 294
Query: 366 KP----TCQDI---DECA-DLIS--TIIMMSVDELQKSVDPQIPELC---GAGSCHNTIG 412
+ C + CA DL T D + +PELC G+
Sbjct: 295 EDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCA 354
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP-AADCINLPGSFQCRCRDGWRGDGA 471
+ P + P ++ LG +P +D +P G
Sbjct: 355 QRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQ 414
Query: 472 TCEDVDECLTN---NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
T D+ TN NG C P T S+RC C+ GY D G C+D+DE
Sbjct: 415 TI-DICRHFTNLCLNGRCLP------TPSSYRCECNVGYTQDVRG--------ECIDVDE 459
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C + P C +G C N PG Y C C GF ++C+
Sbjct: 460 CTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACV 495
Score = 47.6 bits (108), Expect = 1e-04
Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Query: 4 GRCSGPLPTDVLRAVCCCSAL-GKAWGNQRCEPCPKKGTDAYQNLC 48
G+CS P + + CCCS G+ WG+ CE CP++G+ A+Q LC
Sbjct: 2031 GKCSVPKAFNTTKTRCCCSKRPGEGWGDP-CELCPQEGSAAFQELC 2075
Score = 46.0 bits (104), Expect = 4e-04
Identities = 20/35 (57%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V RA CCC G+ WG RCE CP GT AY+ LC
Sbjct: 2326 VTRAECCCGG-GRGWG-PRCELCPLPGTSAYRKLC 2358
Score = 36.3 bits (80), Expect = 0.29
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C LP VCCCS +G WG + CE CP + + +LC
Sbjct: 933 CGVTLPGKYRMDVCCCS-IGAVWGVE-CEACPDPESLEFASLC 973
>AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 3 protein.
Length = 2809
Score = 436 bits (1075), Expect = e-122
Identities = 196/449 (43%), Positives = 252/449 (56%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC FPGLC HG CRN +G F C C G+ D++ C D++EC I +CG G C
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY++ K C+D+DECA + LCRGG C NT GS++C+C G EL
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+C+DIDECS++ G+C +G C N +G +QC C G+ + +
Sbjct: 1106 AKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGG 1165
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C C+NT GSY C+C +G+ L DGR+C D+DEC R C G C N G + C C D
Sbjct: 1166 CDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYD 1225
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A TC D+DEC DL P +C G C NT GSFVC
Sbjct: 1226 GFM--ATPDMRTCVDVDEC-DL-------------------NPHICLHGDCENTKGSFVC 1263
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GY V+ + C+D DECE+G +C A C+N+PGSF CRC GW GDG C D+
Sbjct: 1264 HCQLGYMVR-KGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDL 1322
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC++ C PR C N GS+RC C G+ GDG + C D DECA + LC
Sbjct: 1323 DECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDG---------FFCEDRDECAENVDLC 1373
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+NG C N PGGY C+C++GF D R+C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRAC 1402
Score = 299 bits (734), Expect = 2e-80
Identities = 162/454 (35%), Positives = 214/454 (47%), Gaps = 42/454 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+V+ECA P LC G C N G + C C PG+E +K C D++EC + DG+C G C
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQC 1129
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G+F C C G+++ + CVDI+EC + C C+NT GS+RC CG G L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC-DVHCINTEGSYRCSCGQGYSLM 1188
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
PD +C D+DEC +C G C N G ++C+C +G+ +
Sbjct: 1189 PDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHI 1248
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTC 354
C H C NT GS+ C C+ G+ +R C D+DEC G C C N GS++C C
Sbjct: 1249 CLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRC 1308
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G V G C D+DEC + P+ G C N GS+
Sbjct: 1309 LPGWV----GDGFECHDLDECV------------SQEHRCSPR-------GDCLNVPGSY 1345
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C C G++ G C D DEC D C+N PG ++C C G+ D
Sbjct: 1346 RCTCRQGFA---GDGFFCEDRDEC-AENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRA 1401
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C+DVDEC G +C N G FRC+C+ GY+ D G +C DI+ECA D
Sbjct: 1402 CQDVDECA--QGNLCAFGSCENLPGMFRCICNGGYELDRGG-------GNCTDINECA-D 1451
Query: 533 PTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P C NG C NTPG Y C C F G C+
Sbjct: 1452 PVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Score = 259 bits (634), Expect = 2e-68
Identities = 181/571 (31%), Positives = 248/571 (43%), Gaps = 70/571 (12%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
+G CS + V RA CCCS LG+AWGN CE CP T Y+ LC G PN+
Sbjct: 1502 SGISCSAEIGVGVTRASCCCS-LGRAWGNP-CELCPMANTTEYRTLCPG-GEGFQPNR-- 1556
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNE 121
+T I + DE + G G + +++E
Sbjct: 1557 ------ITVILEDI--DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDE 1608
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C-EIVDGVCGDGDCHN 178
C+ +CG G C N LG +TC C Y + + + C+D+ + C +G C + N
Sbjct: 1609 CSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFN 1668
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
C C +++ C + C + C N A F + G L
Sbjct: 1669 VTRKMCC-CSYNI-GQAWNRPC---EACPTPISPDYQILCGNQAPGFLTDIHTGKPL--- 1720
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
DIDEC IC+NG C NQ+G+++C C G+ +++ CQ
Sbjct: 1721 -----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 299 HS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
+ C+N PGSY C C G+ L + G +C +EC C G C +T GSY C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKL-SPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHR 1834
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G SA + C DIDEC D Q P CG G+C N IGS+ C
Sbjct: 1835 GFQASAD--QTLCMDIDEC-------------------DRQ-P--CGNGTCKNIIGSYNC 1870
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCE 474
C G+ V C D DEC C+N GSF C C+DG+ DG C
Sbjct: 1871 LCFPGFVVT--HNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCV 1928
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D +ECL+ G C P TC N +GSFRC+C G++ C+DIDEC+ +P
Sbjct: 1929 DTNECLSLAGTCLP-GTCQNLEGSFRCICPPGFQVQSD---------HCIDIDECSEEPN 1978
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
LC G C+N+PG ++C C GF + +G C
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 258 bits (633), Expect = 3e-68
Identities = 163/475 (34%), Positives = 220/475 (46%), Gaps = 73/475 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGD 175
++++EC P +C +G C N +G F C+C G+ +S C DV+EC + C + D
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C GYK CV +EC + +C G C++T GS+ C C G +
Sbjct: 1780 CINIPGSYRCKCTRGYKLSP-GGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D+ C DIDEC C NG C+N +G+Y C+C G+ +
Sbjct: 1839 SADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+ C+NT GS+HC C++G+ L ADG++C D +EC A C G C+N GS+ C C
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCIC 1956
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + C DIDEC+ + P LC G+C N+ GSF
Sbjct: 1957 PPGFQVQS----DHCIDIDECS--------------------EEPNLCLFGTCTNSPGSF 1992
Query: 415 VCQCPDGYSVKPEQGPACTDDDE--C----ELGTCDCHPAAD-------CINLPG----- 456
C CP G+ V + G C D + C E G C A + C PG
Sbjct: 1993 QCLCPPGF-VLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGD 2051
Query: 457 -----------SFQCRCRDGW---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+FQ C G G + EDV+EC N G C C NTDGSFRC
Sbjct: 2052 PCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVC-TNGVCVNTDGSFRCE 2110
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECA-NDPTLCENGHCSNTPGGYECDCDVGF 556
C GY D G+ +CVD DEC+ P C G C+N GG+EC C GF
Sbjct: 2111 CPFGYSLDFTGI-------NCVDTDECSVGHP--CGQGTCTNVIGGFECACADGF 2156
Score = 258 bits (631), Expect = 5e-68
Identities = 169/524 (32%), Positives = 227/524 (43%), Gaps = 36/524 (6%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRC-EPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
GGRC+G L R CCC G+ W E CP +G++ +Q LC LLP +
Sbjct: 301 GGRCAGDLAGHYTRRQCCCDR-GRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGL 359
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGE-NXXXXXXXXXXXXXXXXXXXXXXXXQMEVN 120
P +G NG G N ++
Sbjct: 360 FP---------GLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTID 410
Query: 121 ECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTE 180
C F LC +GRC + C+C GY +D + C+DV+EC C GDC N
Sbjct: 411 ICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDEC--TSSPCHHGDCVNIP 467
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
G++ C C PG++A + CVD+DEC + LC GRCVNT GSF+C C G EL+PD
Sbjct: 468 GTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+C D +EC+ TS +C NG C N+ G++ C+C G+ + +
Sbjct: 528 NCVDHNECA-TSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH 586
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCR----NTVGSYTCTCTD 356
C NT GS+ C C G + DGR C D + G C TV C C +
Sbjct: 587 CTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCAN 646
Query: 357 GLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
P +P CQ + E L S+ + ++ D + PE+C G C N
Sbjct: 647 ---PDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR 702
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GD 469
GS+ C C GY G CTD DEC L + C C N PGS+ C C G+ D
Sbjct: 703 GSYRCVCNLGYEA-GASGKDCTDVDECALNSLLCDNGW-CQNSPGSYSCSCPPGFHFWQD 760
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
C+DVDECL++ C C N GS+ C C G + D G
Sbjct: 761 TEICKDVDECLSS--PC-VSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 251 bits (614), Expect = 6e-66
Identities = 155/466 (33%), Positives = 208/466 (44%), Gaps = 32/466 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC P +C G C N+ GG C C+ G+ TCVDV+EC++ +C GDC
Sbjct: 1196 DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCE 1255
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC+ GY + C D+DEC C C+N GSF C C G
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--V 1313
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D C D+DEC CS G C N G+Y+C C +G+A
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL- 1372
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C + C+N PG Y C C G+ D R+C+D+DECA G C G C N G + C C
Sbjct: 1373 -CDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQG-NLCAFGSCENLPGMFRCIC 1430
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTI--IMMSVDELQKSVDPQIPEL--CGAGSCHNT 410
G G C DI+ECAD ++ I + ++ PQ EL G G
Sbjct: 1431 NGGYELDRGGG--NCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTR 1488
Query: 411 IGSFVCQCPD----GYSVKPEQGPACTDDD-ECELGTCDCHPAADC-INLPGSFQCRC-- 462
G+ + D G S E G T C LG +P C + ++ C
Sbjct: 1489 AGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPG 1548
Query: 463 RDGWRGDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
+G++ + T ED+DEC G C C NT GSF+C C GY +
Sbjct: 1549 GEGFQPNRITVILEDIDECQELPGLCQ-GGDCVNTFGSFQCECPPGYHLSEH-------T 1600
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DIDEC+ ++C G C NT G Y C C + + G +C+
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCM 1646
Score = 247 bits (604), Expect = 9e-65
Identities = 156/461 (33%), Positives = 199/461 (43%), Gaps = 31/461 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNECA PG+C +G C N G F C+C GY D CVD +EC V CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCT 2142
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G F C C G++ C DIDEC+ N LC RC NT GS+ C C G L
Sbjct: 2143 NVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLC-AFRCHNTEGSYLCTCPAGYTLRE 2200
Query: 238 DRLSCKDIDECSITSGIC-SNG-ACENQMGTYQCVCDEGYAQSTVKSHX-XXXXXXXXXX 294
D C+D+DEC+ C + G C+N +GT+ CVC G
Sbjct: 2201 DGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQP 2260
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN-TVGSYTC 352
C + CVNT GS+ C C EG+ C DI + A CR+ + S
Sbjct: 2261 DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVL-QTMCRSLSSSSEAV 2319
Query: 353 TCTDGLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
T + G P C+ L + + + LC G C
Sbjct: 2320 TRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGEC 2379
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW- 466
N++GSF C C GY+ C D DEC C C N GSF C C G+
Sbjct: 2380 INSLGSFRCHCQAGYT-PDATATTCLDMDECSQVPKPC--TFLCKNTKGSFLCSCPRGYL 2436
Query: 467 -RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
DG TC+D+DEC + C + C NT G+F C C G+ +C D
Sbjct: 2437 LEEDGRTCKDLDECTSRQHNC--QFLCVNTVGAFTCRCPPGFTQHH---------QACFD 2485
Query: 526 IDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DEC+ P C +GHC NTPG + C+C GFT + G C
Sbjct: 2486 NDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGC 2526
Score = 243 bits (594), Expect = 2e-63
Identities = 157/448 (35%), Positives = 205/448 (45%), Gaps = 74/448 (16%)
Query: 157 TCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI-----------DE 205
TC DVNECE GVC +G C NT GSF C C G D ++CVD+ DE
Sbjct: 866 TCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDE 925
Query: 206 CADN-DALCRGGRCVNTAGSF---RCE-------------CGHGMELAP-DRLS----CK 243
C R C + G+ CE C G+ A D LS K
Sbjct: 926 CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYK 985
Query: 244 DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHSCV 302
D++EC + G+C++G C N +G++ C C G+A + + C Q +CV
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 303 NTPGSYHCTCREGWHLR-ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
NTPGS+ C C G+ ++C D+DECA C GG C NT GSY C C G +
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
A G C+DIDEC S+ + LC G C N IG+F C C G
Sbjct: 1106 AKGT--ACEDIDEC----------SLSD----------GLCPHGQCVNVIGAFQCSCHAG 1143
Query: 422 YSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVD 477
+ P++ C D +EC + G CD H CIN GS++C C G+ DG C DVD
Sbjct: 1144 FQSTPDR-QGCVDINECRVQNGGCDVH----CINTEGSYRCSCGQGYSLMPDGRACADVD 1198
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC N C + C N G RCLC G+ +RT CVD+DEC +P +C
Sbjct: 1199 ECEENPRVC-DQGHCTNMPGGHRCLCYDGFMATP-DMRT------CVDVDECDLNPHICL 1250
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
+G C NT G + C C +G+ C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGC 1278
Score = 239 bits (586), Expect = 1e-62
Identities = 169/500 (33%), Positives = 218/500 (43%), Gaps = 87/500 (17%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC + P C HG C N+ G + C C+PG++ CVDV+EC + G+C G C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NTEGSF C C G++ K CVD +ECA + +C G C+N GSF C C G LA
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATS-TMCVNGVCLNEDGSFSCLCKPGFLLA 564
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTY--QC-----------VCDEGYAQST---- 279
P C DIDEC T GIC NG C N G++ QC VC + + +ST
Sbjct: 565 PGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 280 --------------VKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
KS CQ + C G + DGR
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 326 RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
DI+ECA C G C N GSY C C G A+G C D+DECA
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKD--CTDVDECA--------- 729
Query: 386 SVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
++ L LC G C N+ GS+ C CP G+ + C D DEC C
Sbjct: 730 -LNSL----------LCDNGWCQNSPGSYSCSCPPGFHFWQDT-EICKDVDECLSSPC-- 775
Query: 446 HPAADCINLPGSFQCRCRDGWRGD--GATCED---------VDE--CLTNNGGCHPRATC 492
+ C NL GS+ C+C G R D G C D + E C N G R+ C
Sbjct: 776 -VSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSEC 834
Query: 493 ANTDGSF------RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG 546
T G+ RC D G+ T +C D++EC + P +C NG C NT G
Sbjct: 835 CATLGAAWGSPCERCEIDPAC-ARGFARMTGV---TCDDVNECESFPGVCPNGRCVNTAG 890
Query: 547 GYECDCDVGFTRAADGRSCL 566
+ C+C G A GR C+
Sbjct: 891 SFRCECPEGLMLDASGRLCV 910
Score = 239 bits (584), Expect = 2e-62
Identities = 154/457 (33%), Positives = 206/457 (45%), Gaps = 63/457 (13%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG-D 175
+++EC+ P LC RC N G + C C GY C DV+EC C G +
Sbjct: 2166 DIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGME 2224
Query: 176 CHNTEGSFTCHCRPGYKADDFS-KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C N G+F C C PG + S + C D +EC LC GRCVNTAGSFRC+C G +
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 235 LAPDRLSCKDIDE----CSITSGICSNGACENQMGTY-QCVCDEGYAQSTVKSHXXXXXX 289
+P C DI + + +C + + ++ T +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGP---------- 2334
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
RC+ + +Y C G A+GR D+DEC A C G+C N++GS
Sbjct: 2335 ------RCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLCAHGECINSLGS 2385
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
+ C C G P A TC D+DEC+ Q+P+ C C N
Sbjct: 2386 FRCHCQAGYTPDATAT--TCLDMDECS--------------------QVPKPC-TFLCKN 2422
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
T GSF+C CP GY ++ E G C D DEC +C C+N G+F CRC G+
Sbjct: 2423 TKGSFLCSCPRGYLLE-EDGRTCKDLDECTSRQHNCQFL--CVNTVGAFTCRCPPGFTQH 2479
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
C D DEC G C C NT GSFRC C G+ V + C D++EC
Sbjct: 2480 HQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGF-------TLVSSGHGCEDVNEC 2532
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ P C++G C N GGY C C GFT+ + C+
Sbjct: 2533 -DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCV 2567
Score = 231 bits (564), Expect = 7e-60
Identities = 159/484 (32%), Positives = 212/484 (43%), Gaps = 73/484 (15%)
Query: 118 EVNECAAFPGLCGHGR---CRNLLGGFTCDCFPGYEK-DSKNHTCVDVNECEIVDGVCGD 173
+V+ECA C H R C+NL+G F C C PG C D NEC +C +
Sbjct: 2207 DVDECADGQQDC-HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVN 2265
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDE--CADN--DALCRGGRCVNTAGS-FRCE 228
G C NT GSF C C G++ C DI + C +CR + A + C
Sbjct: 2266 GRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECC 2325
Query: 229 CGHGM------ELAP------DRLSC----------KDIDECSITSGICSNGACENQMGT 266
CG G EL P R C +D+DEC + + +C++G C N +G+
Sbjct: 2326 CGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGS 2385
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR 326
++C C GY + C C NT GS+ C+C G+ L DGR+C+
Sbjct: 2386 FRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
D+DEC C C NTVG++TC C G C D DEC+
Sbjct: 2446 DLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFTQH----HQACFDNDECSAQ-------- 2492
Query: 387 VDELQKSVDPQIPELCGA-GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
P CGA G CHNT GSF C+C G+++ G C D +EC+ G C
Sbjct: 2493 ------------PGPCGAHGHCHNTPGSFRCECHQGFTLV-SSGHGCEDVNECD-GPHRC 2538
Query: 446 HPAADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N G ++C C G+ A C D +EC + C A+C NT G FRC+C
Sbjct: 2539 QHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGS-ASCRNTLGGFRCVC 2595
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGR 563
+G+ D + C D+DECA C C+NTPGG+ C C G+ RA G
Sbjct: 2596 PSGFDFDQ-------ALGGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQGH 2647
Query: 564 SCLG 567
G
Sbjct: 2648 CVSG 2651
Score = 230 bits (563), Expect = 9e-60
Identities = 151/465 (32%), Positives = 209/465 (44%), Gaps = 52/465 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C C GYE + C DV+EC + +C +G C
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQ 741
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N+ GS++C C PG+ ++IC D+DEC + C G C N AGS+ C+CG G L P
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDP 799
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
C D T G C E++ C+ ++++S C
Sbjct: 800 SGTFCLD-----STKGTCWLKIQESR-------CEVNLQGASLRSE-CCATLGAAWGSPC 846
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+ C P C G+ R G +C D++EC C G+C NT GS+ C C +G
Sbjct: 847 ER-CEIDP-----ACARGF-ARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEG 899
Query: 358 LVPSAAGAKPTCQDI-----------DECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
L+ A+G C D+ DEC + M D S+ C A
Sbjct: 900 LMLDASGR--LCVDVRLEPCFLRWDEDECGVTLPGKYRM--DVCCCSIGAVWGVECEACP 955
Query: 407 CHNTIGSFVCQCPDGYSVKPEQ----GPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
++ F CP G P D +EC++ C C N GSF C C
Sbjct: 956 DPESL-EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCAC 1013
Query: 463 RDGWRGDG--ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ D C D+DEC + C + TC NT GSF C C GY+ G+ L +
Sbjct: 1014 AGGFALDAQERNCTDIDECRISPDLC-GQGTCVNTPGSFECECFPGYE-SGFML-----M 1066
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+C+D+DECA DP LC G C+NT G Y+C C G A G +C
Sbjct: 1067 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 230 bits (562), Expect = 1e-59
Identities = 165/510 (32%), Positives = 215/510 (42%), Gaps = 94/510 (18%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C--EIVDGVCG 172
++++EC+ P LC G C N G F C C PG+ H C D + C G C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCS 2027
Query: 173 DGDCHN-TEGSFTCHCRPGYKADD------------FSKIC--------------VDIDE 205
N T+ C RPG D F ++C D++E
Sbjct: 2028 VPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNE 2087
Query: 206 CADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMG 265
CA+N +C G CVNT GSFRCEC G L ++C D DECS+ C G C N +G
Sbjct: 2088 CAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-GHPCGQGTCTNVIG 2146
Query: 266 TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
++C C +G+ + + C C NT GSY CTC G+ LR DG C
Sbjct: 2147 GFECACADGFEPGLMMT-CEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMC 2205
Query: 326 RDIDECAGGARPC--GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
RD+DECA G + C G +C+N +G++ C C G+ P G+ C D +EC
Sbjct: 2206 RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRP-LPGSGEGCTDDNEC-------- 2256
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKP--------EQGPA---- 431
Q P+LC G C NT GSF C C +G+ P QGP
Sbjct: 2257 -----HAQ-------PDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Query: 432 ----C----TDDDECELGTCDC------HPAADCINLPGSFQCR--CRDGWRGDGATCED 475
C + + C C P + LPG+ R C G G A D
Sbjct: 2305 LQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG-SGYTAEGRD 2363
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
VDEC C C N+ GSFRC C GY D +C+D+DEC+ P
Sbjct: 2364 VDECRMLAHLC-AHGECINSLGSFRCHCQAGYTPD-------ATATTCLDMDECSQVPKP 2415
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C NT G + C C G+ DGR+C
Sbjct: 2416 C-TFLCKNTKGSFLCSCPRGYLLEEDGRTC 2444
Score = 195 bits (475), Expect = 4e-49
Identities = 135/431 (31%), Positives = 183/431 (42%), Gaps = 60/431 (13%)
Query: 147 PGYEKDSKNHTCV---DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
PG E N V D++EC+ + G+C GDC NT GSF C C PGY + ++IC DI
Sbjct: 1547 PGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDI 1606
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC+ + ++C G C NT G++ C C +C D+ + NG C+N+
Sbjct: 1607 DECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNE 1664
Query: 264 MG----TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
+ C C Q+ + Q C N + G L
Sbjct: 1665 LAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDY---QILCGNQAPGFLTDIHTGKPL- 1720
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
DIDEC C G C N +GS+ C C G + C+D+DEC
Sbjct: 1721 -------DIDECGEIPAICANGICINQIGSFRCECPAGF--NYNSILLACEDVDECGSRE 1771
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC- 438
S Q++ D C N GS+ C+C GY + P G AC +EC
Sbjct: 1772 SPC--------QQNAD-----------CINIPGSYRCKCTRGYKLSP--GGACVGRNECR 1810
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTD 496
E+ H DC++ GS+ C C G++ D C D+DEC G TC N
Sbjct: 1811 EIPNVCSH--GDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG---NGTCKNII 1865
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN-DPTLCENGHCSNTPGGYECDCDVG 555
GS+ CLC G+ G CVD DEC +C GHC NT G + C C G
Sbjct: 1866 GSYNCLCFPGFVVTHNG--------DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDG 1917
Query: 556 FTRAADGRSCL 566
F ADG++C+
Sbjct: 1918 FELTADGKNCV 1928
Score = 168 bits (408), Expect = 5e-41
Identities = 88/250 (35%), Positives = 118/250 (47%), Gaps = 9/250 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC+ P C C+N G F C C GY + TC D++EC C C
Sbjct: 2404 LDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC-QFLC 2461
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G+FTC C PG+ + C D DEC+ C G C NT GSFRCEC G L
Sbjct: 2462 VNTVGAFTCRCPPGFT--QHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTL 2519
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
C+D++EC C +G C+NQ+G Y+C C +G+ Q + +
Sbjct: 2520 VSSGHGCEDVNECDGPHR-CQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPP 2577
Query: 296 RC-QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C SC NT G + C C G+ C+D+DECAG PC C NT G + C C
Sbjct: 2578 TCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPC-SYSCANTPGGFLCGC 2636
Query: 355 TDGLVPSAAG 364
G + G
Sbjct: 2637 PQGYFRAGQG 2646
Score = 136 bits (329), Expect = 2e-31
Identities = 122/399 (30%), Positives = 155/399 (38%), Gaps = 60/399 (15%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD--VNEC--EIVDGVC-G 172
+V+EC A PGLC G C N++G F C C G+ + C D C + G C G
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAG 306
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDE------CADNDALCRGGRCVNTAGSFR 226
D H T C + A ++C CA L G +
Sbjct: 307 DLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGF 366
Query: 227 CECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
G G L P RL+ D GI S G + +GT A
Sbjct: 367 GSNGMGPPLGPARLNPHGSD----ARGIPSLGPGNSNIGT---------ATLNQTIDICR 413
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT 346
RC + TP SY C C G+ G C D+DEC + PC G C N
Sbjct: 414 HFTNLCLNGRC----LPTPSSYRCECNVGYTQDVRG-ECIDVDECT--SSPCHHGDCVNI 466
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
G+Y C C G A + C D+DEC ++S LC G
Sbjct: 467 PGTYHCRCYPGF--QATPTRQACVDVDEC--IVS------------------GGLCHLGR 504
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C NT GSF C C G+ + P+ G C D +EC T + C+N GSF C C+ G+
Sbjct: 505 CVNTEGSFQCVCNAGFELSPD-GKNCVDHNECATSTMCVNGV--CLNEDGSFSCLCKPGF 561
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
G C D+DEC T G C NT+GSFRC C
Sbjct: 562 LLAPGGHYCMDIDECQT--PGICVNGHCTNTEGSFRCQC 598
Score = 134 bits (324), Expect = 8e-31
Identities = 86/241 (35%), Positives = 105/241 (43%), Gaps = 39/241 (16%)
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
ID C C G+C T SY C C G G C D+DEC
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE---CIDVDECTS---------- 455
Query: 388 DELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
P C G C N G++ C+C G+ P + AC D DEC + CH
Sbjct: 456 -------SP-----CHHGDCVNIPGTYHCRCYPGFQATPTR-QACVDVDECIVSGGLCH- 501
Query: 448 AADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
C+N GSFQC C G+ DG C D +EC T+ C C N DGSF CLC
Sbjct: 502 LGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM-C-VNGVCLNEDGSFSCLCKP 559
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G+ G + C+DIDEC P +C NGHC+NT G + C C G DGR C
Sbjct: 560 GFLLAPGG-------HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC 611
Query: 566 L 566
+
Sbjct: 612 V 612
Score = 82.6 bits (195), Expect = 3e-15
Identities = 117/458 (25%), Positives = 154/458 (33%), Gaps = 54/458 (11%)
Query: 136 NLLGG-FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKAD 194
N+ G F C PG+ CV I CG+G C C C G A
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV----VPICRRACGEGFCSQPN---LCTCADGTLAP 110
Query: 195 D--FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM--ELAPDRLSCKDIDECSI 250
S+ C N CRG C+ G CG + + C + C+
Sbjct: 111 SCGVSRGSGCSVSCM-NGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCAC 169
Query: 251 TSGICSNGACENQMGTYQC---VCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
G CE T C V EG C P
Sbjct: 170 VYGFMGP-QCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQ 228
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSAAGA 365
H CR G+ +C+D+DEC C GG C N VGS+ C C G L S+A
Sbjct: 229 PH-PCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 366 KP----TCQDI---DECA-DLIS--TIIMMSVDELQKSVDPQIPELC---GAGSCHNTIG 412
+ C + CA DL T D + +PELC G+
Sbjct: 288 EDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCA 347
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP-AADCINLPGSFQCRCRDGWRGDGA 471
+ P + P ++ LG +P +D +P G
Sbjct: 348 QRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQ 407
Query: 472 TCEDVDECLTN---NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
T D+ TN NG C P T S+RC C+ GY D G C+D+DE
Sbjct: 408 TI-DICRHFTNLCLNGRCLP------TPSSYRCECNVGYTQDVRG--------ECIDVDE 452
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C + P C +G C N PG Y C C GF ++C+
Sbjct: 453 CTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACV 488
Score = 47.6 bits (108), Expect = 1e-04
Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Query: 4 GRCSGPLPTDVLRAVCCCSAL-GKAWGNQRCEPCPKKGTDAYQNLC 48
G+CS P + + CCCS G+ WG+ CE CP++G+ A+Q LC
Sbjct: 2024 GKCSVPKAFNTTKTRCCCSKRPGEGWGDP-CELCPQEGSAAFQELC 2068
Score = 46.0 bits (104), Expect = 4e-04
Identities = 20/35 (57%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V RA CCC G+ WG RCE CP GT AY+ LC
Sbjct: 2319 VTRAECCCGG-GRGWG-PRCELCPLPGTSAYRKLC 2351
Score = 36.3 bits (80), Expect = 0.29
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C LP VCCCS +G WG + CE CP + + +LC
Sbjct: 926 CGVTLPGKYRMDVCCCS-IGAVWGVE-CEACPDPESLEFASLC 966
>AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 2 protein.
Length = 2809
Score = 436 bits (1075), Expect = e-122
Identities = 196/449 (43%), Positives = 252/449 (56%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC FPGLC HG CRN +G F C C G+ D++ C D++EC I +CG G C
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY++ K C+D+DECA + LCRGG C NT GS++C+C G EL
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+C+DIDECS++ G+C +G C N +G +QC C G+ + +
Sbjct: 1106 AKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGG 1165
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C C+NT GSY C+C +G+ L DGR+C D+DEC R C G C N G + C C D
Sbjct: 1166 CDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYD 1225
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A TC D+DEC DL P +C G C NT GSFVC
Sbjct: 1226 GFM--ATPDMRTCVDVDEC-DL-------------------NPHICLHGDCENTKGSFVC 1263
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GY V+ + C+D DECE+G +C A C+N+PGSF CRC GW GDG C D+
Sbjct: 1264 HCQLGYMVR-KGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDL 1322
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC++ C PR C N GS+RC C G+ GDG + C D DECA + LC
Sbjct: 1323 DECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDG---------FFCEDRDECAENVDLC 1373
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+NG C N PGGY C+C++GF D R+C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRAC 1402
Score = 299 bits (734), Expect = 2e-80
Identities = 162/454 (35%), Positives = 214/454 (47%), Gaps = 42/454 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+V+ECA P LC G C N G + C C PG+E +K C D++EC + DG+C G C
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQC 1129
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G+F C C G+++ + CVDI+EC + C C+NT GS+RC CG G L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC-DVHCINTEGSYRCSCGQGYSLM 1188
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
PD +C D+DEC +C G C N G ++C+C +G+ +
Sbjct: 1189 PDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHI 1248
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTC 354
C H C NT GS+ C C+ G+ +R C D+DEC G C C N GS++C C
Sbjct: 1249 CLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRC 1308
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G V G C D+DEC + P+ G C N GS+
Sbjct: 1309 LPGWV----GDGFECHDLDECV------------SQEHRCSPR-------GDCLNVPGSY 1345
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C C G++ G C D DEC D C+N PG ++C C G+ D
Sbjct: 1346 RCTCRQGFA---GDGFFCEDRDEC-AENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRA 1401
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C+DVDEC G +C N G FRC+C+ GY+ D G +C DI+ECA D
Sbjct: 1402 CQDVDECA--QGNLCAFGSCENLPGMFRCICNGGYELDRGG-------GNCTDINECA-D 1451
Query: 533 PTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P C NG C NTPG Y C C F G C+
Sbjct: 1452 PVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Score = 259 bits (634), Expect = 2e-68
Identities = 181/571 (31%), Positives = 248/571 (43%), Gaps = 70/571 (12%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
+G CS + V RA CCCS LG+AWGN CE CP T Y+ LC G PN+
Sbjct: 1502 SGISCSAEIGVGVTRASCCCS-LGRAWGNP-CELCPMANTTEYRTLCPG-GEGFQPNR-- 1556
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNE 121
+T I + DE + G G + +++E
Sbjct: 1557 ------ITVILEDI--DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDE 1608
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C-EIVDGVCGDGDCHN 178
C+ +CG G C N LG +TC C Y + + + C+D+ + C +G C + N
Sbjct: 1609 CSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFN 1668
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
C C +++ C + C + C N A F + G L
Sbjct: 1669 VTRKMCC-CSYNI-GQAWNRPC---EACPTPISPDYQILCGNQAPGFLTDIHTGKPL--- 1720
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
DIDEC IC+NG C NQ+G+++C C G+ +++ CQ
Sbjct: 1721 -----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 299 HS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
+ C+N PGSY C C G+ L + G +C +EC C G C +T GSY C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKL-SPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHR 1834
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G SA + C DIDEC D Q P CG G+C N IGS+ C
Sbjct: 1835 GFQASAD--QTLCMDIDEC-------------------DRQ-P--CGNGTCKNIIGSYNC 1870
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCE 474
C G+ V C D DEC C+N GSF C C+DG+ DG C
Sbjct: 1871 LCFPGFVVT--HNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCV 1928
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D +ECL+ G C P TC N +GSFRC+C G++ C+DIDEC+ +P
Sbjct: 1929 DTNECLSLAGTCLP-GTCQNLEGSFRCICPPGFQVQSD---------HCIDIDECSEEPN 1978
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
LC G C+N+PG ++C C GF + +G C
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 258 bits (633), Expect = 3e-68
Identities = 163/475 (34%), Positives = 220/475 (46%), Gaps = 73/475 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGD 175
++++EC P +C +G C N +G F C+C G+ +S C DV+EC + C + D
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C GYK CV +EC + +C G C++T GS+ C C G +
Sbjct: 1780 CINIPGSYRCKCTRGYKLSP-GGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D+ C DIDEC C NG C+N +G+Y C+C G+ +
Sbjct: 1839 SADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+ C+NT GS+HC C++G+ L ADG++C D +EC A C G C+N GS+ C C
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCIC 1956
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + C DIDEC+ + P LC G+C N+ GSF
Sbjct: 1957 PPGFQVQS----DHCIDIDECS--------------------EEPNLCLFGTCTNSPGSF 1992
Query: 415 VCQCPDGYSVKPEQGPACTDDDE--C----ELGTCDCHPAAD-------CINLPG----- 456
C CP G+ V + G C D + C E G C A + C PG
Sbjct: 1993 QCLCPPGF-VLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGD 2051
Query: 457 -----------SFQCRCRDGW---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+FQ C G G + EDV+EC N G C C NTDGSFRC
Sbjct: 2052 PCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVC-TNGVCVNTDGSFRCE 2110
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECA-NDPTLCENGHCSNTPGGYECDCDVGF 556
C GY D G+ +CVD DEC+ P C G C+N GG+EC C GF
Sbjct: 2111 CPFGYSLDFTGI-------NCVDTDECSVGHP--CGQGTCTNVIGGFECACADGF 2156
Score = 258 bits (631), Expect = 5e-68
Identities = 169/524 (32%), Positives = 227/524 (43%), Gaps = 36/524 (6%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRC-EPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
GGRC+G L R CCC G+ W E CP +G++ +Q LC LLP +
Sbjct: 301 GGRCAGDLAGHYTRRQCCCDR-GRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGL 359
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGE-NXXXXXXXXXXXXXXXXXXXXXXXXQMEVN 120
P +G NG G N ++
Sbjct: 360 FP---------GLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTID 410
Query: 121 ECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTE 180
C F LC +GRC + C+C GY +D + C+DV+EC C GDC N
Sbjct: 411 ICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDEC--TSSPCHHGDCVNIP 467
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
G++ C C PG++A + CVD+DEC + LC GRCVNT GSF+C C G EL+PD
Sbjct: 468 GTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+C D +EC+ TS +C NG C N+ G++ C+C G+ + +
Sbjct: 528 NCVDHNECA-TSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH 586
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCR----NTVGSYTCTCTD 356
C NT GS+ C C G + DGR C D + G C TV C C +
Sbjct: 587 CTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCAN 646
Query: 357 GLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
P +P CQ + E L S+ + ++ D + PE+C G C N
Sbjct: 647 ---PDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR 702
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GD 469
GS+ C C GY G CTD DEC L + C C N PGS+ C C G+ D
Sbjct: 703 GSYRCVCNLGYEA-GASGKDCTDVDECALNSLLCDNGW-CQNSPGSYSCSCPPGFHFWQD 760
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
C+DVDECL++ C C N GS+ C C G + D G
Sbjct: 761 TEICKDVDECLSS--PC-VSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 251 bits (614), Expect = 6e-66
Identities = 155/466 (33%), Positives = 208/466 (44%), Gaps = 32/466 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC P +C G C N+ GG C C+ G+ TCVDV+EC++ +C GDC
Sbjct: 1196 DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCE 1255
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC+ GY + C D+DEC C C+N GSF C C G
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--V 1313
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D C D+DEC CS G C N G+Y+C C +G+A
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL- 1372
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C + C+N PG Y C C G+ D R+C+D+DECA G C G C N G + C C
Sbjct: 1373 -CDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQG-NLCAFGSCENLPGMFRCIC 1430
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTI--IMMSVDELQKSVDPQIPEL--CGAGSCHNT 410
G G C DI+ECAD ++ I + ++ PQ EL G G
Sbjct: 1431 NGGYELDRGGG--NCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTR 1488
Query: 411 IGSFVCQCPD----GYSVKPEQGPACTDDD-ECELGTCDCHPAADC-INLPGSFQCRC-- 462
G+ + D G S E G T C LG +P C + ++ C
Sbjct: 1489 AGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPG 1548
Query: 463 RDGWRGDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
+G++ + T ED+DEC G C C NT GSF+C C GY +
Sbjct: 1549 GEGFQPNRITVILEDIDECQELPGLCQ-GGDCVNTFGSFQCECPPGYHLSEH-------T 1600
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DIDEC+ ++C G C NT G Y C C + + G +C+
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCM 1646
Score = 247 bits (604), Expect = 9e-65
Identities = 156/461 (33%), Positives = 199/461 (43%), Gaps = 31/461 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNECA PG+C +G C N G F C+C GY D CVD +EC V CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCT 2142
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G F C C G++ C DIDEC+ N LC RC NT GS+ C C G L
Sbjct: 2143 NVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLC-AFRCHNTEGSYLCTCPAGYTLRE 2200
Query: 238 DRLSCKDIDECSITSGIC-SNG-ACENQMGTYQCVCDEGYAQSTVKSHX-XXXXXXXXXX 294
D C+D+DEC+ C + G C+N +GT+ CVC G
Sbjct: 2201 DGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQP 2260
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN-TVGSYTC 352
C + CVNT GS+ C C EG+ C DI + A CR+ + S
Sbjct: 2261 DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVL-QTMCRSLSSSSEAV 2319
Query: 353 TCTDGLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
T + G P C+ L + + + LC G C
Sbjct: 2320 TRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGEC 2379
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW- 466
N++GSF C C GY+ C D DEC C C N GSF C C G+
Sbjct: 2380 INSLGSFRCHCQAGYT-PDATATTCLDMDECSQVPKPC--TFLCKNTKGSFLCSCPRGYL 2436
Query: 467 -RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
DG TC+D+DEC + C + C NT G+F C C G+ +C D
Sbjct: 2437 LEEDGRTCKDLDECTSRQHNC--QFLCVNTVGAFTCRCPPGFTQHH---------QACFD 2485
Query: 526 IDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DEC+ P C +GHC NTPG + C+C GFT + G C
Sbjct: 2486 NDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGC 2526
Score = 243 bits (594), Expect = 2e-63
Identities = 157/448 (35%), Positives = 205/448 (45%), Gaps = 74/448 (16%)
Query: 157 TCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI-----------DE 205
TC DVNECE GVC +G C NT GSF C C G D ++CVD+ DE
Sbjct: 866 TCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDE 925
Query: 206 CADN-DALCRGGRCVNTAGSF---RCE-------------CGHGMELAP-DRLS----CK 243
C R C + G+ CE C G+ A D LS K
Sbjct: 926 CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYK 985
Query: 244 DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHSCV 302
D++EC + G+C++G C N +G++ C C G+A + + C Q +CV
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 303 NTPGSYHCTCREGWHLR-ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
NTPGS+ C C G+ ++C D+DECA C GG C NT GSY C C G +
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
A G C+DIDEC S+ + LC G C N IG+F C C G
Sbjct: 1106 AKGT--ACEDIDEC----------SLSD----------GLCPHGQCVNVIGAFQCSCHAG 1143
Query: 422 YSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVD 477
+ P++ C D +EC + G CD H CIN GS++C C G+ DG C DVD
Sbjct: 1144 FQSTPDR-QGCVDINECRVQNGGCDVH----CINTEGSYRCSCGQGYSLMPDGRACADVD 1198
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC N C + C N G RCLC G+ +RT CVD+DEC +P +C
Sbjct: 1199 ECEENPRVC-DQGHCTNMPGGHRCLCYDGFMATP-DMRT------CVDVDECDLNPHICL 1250
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
+G C NT G + C C +G+ C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGC 1278
Score = 239 bits (586), Expect = 1e-62
Identities = 169/500 (33%), Positives = 218/500 (43%), Gaps = 87/500 (17%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC + P C HG C N+ G + C C+PG++ CVDV+EC + G+C G C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NTEGSF C C G++ K CVD +ECA + +C G C+N GSF C C G LA
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATS-TMCVNGVCLNEDGSFSCLCKPGFLLA 564
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTY--QC-----------VCDEGYAQST---- 279
P C DIDEC T GIC NG C N G++ QC VC + + +ST
Sbjct: 565 PGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 280 --------------VKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
KS CQ + C G + DGR
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 326 RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
DI+ECA C G C N GSY C C G A+G C D+DECA
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKD--CTDVDECA--------- 729
Query: 386 SVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
++ L LC G C N+ GS+ C CP G+ + C D DEC C
Sbjct: 730 -LNSL----------LCDNGWCQNSPGSYSCSCPPGFHFWQDT-EICKDVDECLSSPC-- 775
Query: 446 HPAADCINLPGSFQCRCRDGWRGD--GATCED---------VDE--CLTNNGGCHPRATC 492
+ C NL GS+ C+C G R D G C D + E C N G R+ C
Sbjct: 776 -VSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSEC 834
Query: 493 ANTDGSF------RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG 546
T G+ RC D G+ T +C D++EC + P +C NG C NT G
Sbjct: 835 CATLGAAWGSPCERCEIDPAC-ARGFARMTGV---TCDDVNECESFPGVCPNGRCVNTAG 890
Query: 547 GYECDCDVGFTRAADGRSCL 566
+ C+C G A GR C+
Sbjct: 891 SFRCECPEGLMLDASGRLCV 910
Score = 239 bits (584), Expect = 2e-62
Identities = 154/457 (33%), Positives = 206/457 (45%), Gaps = 63/457 (13%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG-D 175
+++EC+ P LC RC N G + C C GY C DV+EC C G +
Sbjct: 2166 DIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGME 2224
Query: 176 CHNTEGSFTCHCRPGYKADDFS-KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C N G+F C C PG + S + C D +EC LC GRCVNTAGSFRC+C G +
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 235 LAPDRLSCKDIDE----CSITSGICSNGACENQMGTY-QCVCDEGYAQSTVKSHXXXXXX 289
+P C DI + + +C + + ++ T +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGP---------- 2334
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
RC+ + +Y C G A+GR D+DEC A C G+C N++GS
Sbjct: 2335 ------RCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLCAHGECINSLGS 2385
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
+ C C G P A TC D+DEC+ Q+P+ C C N
Sbjct: 2386 FRCHCQAGYTPDATAT--TCLDMDECS--------------------QVPKPC-TFLCKN 2422
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
T GSF+C CP GY ++ E G C D DEC +C C+N G+F CRC G+
Sbjct: 2423 TKGSFLCSCPRGYLLE-EDGRTCKDLDECTSRQHNCQFL--CVNTVGAFTCRCPPGFTQH 2479
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
C D DEC G C C NT GSFRC C G+ V + C D++EC
Sbjct: 2480 HQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGF-------TLVSSGHGCEDVNEC 2532
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ P C++G C N GGY C C GFT+ + C+
Sbjct: 2533 -DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCV 2567
Score = 231 bits (564), Expect = 7e-60
Identities = 159/484 (32%), Positives = 212/484 (43%), Gaps = 73/484 (15%)
Query: 118 EVNECAAFPGLCGHGR---CRNLLGGFTCDCFPGYEK-DSKNHTCVDVNECEIVDGVCGD 173
+V+ECA C H R C+NL+G F C C PG C D NEC +C +
Sbjct: 2207 DVDECADGQQDC-HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVN 2265
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDE--CADN--DALCRGGRCVNTAGS-FRCE 228
G C NT GSF C C G++ C DI + C +CR + A + C
Sbjct: 2266 GRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECC 2325
Query: 229 CGHGM------ELAP------DRLSC----------KDIDECSITSGICSNGACENQMGT 266
CG G EL P R C +D+DEC + + +C++G C N +G+
Sbjct: 2326 CGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGS 2385
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR 326
++C C GY + C C NT GS+ C+C G+ L DGR+C+
Sbjct: 2386 FRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
D+DEC C C NTVG++TC C G C D DEC+
Sbjct: 2446 DLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFTQH----HQACFDNDECSAQ-------- 2492
Query: 387 VDELQKSVDPQIPELCGA-GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
P CGA G CHNT GSF C+C G+++ G C D +EC+ G C
Sbjct: 2493 ------------PGPCGAHGHCHNTPGSFRCECHQGFTLV-SSGHGCEDVNECD-GPHRC 2538
Query: 446 HPAADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N G ++C C G+ A C D +EC + C A+C NT G FRC+C
Sbjct: 2539 QHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGS-ASCRNTLGGFRCVC 2595
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGR 563
+G+ D + C D+DECA C C+NTPGG+ C C G+ RA G
Sbjct: 2596 PSGFDFDQ-------ALGGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQGH 2647
Query: 564 SCLG 567
G
Sbjct: 2648 CVSG 2651
Score = 230 bits (563), Expect = 9e-60
Identities = 151/465 (32%), Positives = 209/465 (44%), Gaps = 52/465 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C C GYE + C DV+EC + +C +G C
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQ 741
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N+ GS++C C PG+ ++IC D+DEC + C G C N AGS+ C+CG G L P
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDP 799
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
C D T G C E++ C+ ++++S C
Sbjct: 800 SGTFCLD-----STKGTCWLKIQESR-------CEVNLQGASLRSE-CCATLGAAWGSPC 846
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+ C P C G+ R G +C D++EC C G+C NT GS+ C C +G
Sbjct: 847 ER-CEIDP-----ACARGF-ARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEG 899
Query: 358 LVPSAAGAKPTCQDI-----------DECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
L+ A+G C D+ DEC + M D S+ C A
Sbjct: 900 LMLDASGR--LCVDVRLEPCFLRWDEDECGVTLPGKYRM--DVCCCSIGAVWGVECEACP 955
Query: 407 CHNTIGSFVCQCPDGYSVKPEQ----GPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
++ F CP G P D +EC++ C C N GSF C C
Sbjct: 956 DPESL-EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCAC 1013
Query: 463 RDGWRGDG--ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ D C D+DEC + C + TC NT GSF C C GY+ G+ L +
Sbjct: 1014 AGGFALDAQERNCTDIDECRISPDLC-GQGTCVNTPGSFECECFPGYE-SGFML-----M 1066
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+C+D+DECA DP LC G C+NT G Y+C C G A G +C
Sbjct: 1067 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 230 bits (562), Expect = 1e-59
Identities = 165/510 (32%), Positives = 215/510 (42%), Gaps = 94/510 (18%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C--EIVDGVCG 172
++++EC+ P LC G C N G F C C PG+ H C D + C G C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCS 2027
Query: 173 DGDCHN-TEGSFTCHCRPGYKADD------------FSKIC--------------VDIDE 205
N T+ C RPG D F ++C D++E
Sbjct: 2028 VPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNE 2087
Query: 206 CADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMG 265
CA+N +C G CVNT GSFRCEC G L ++C D DECS+ C G C N +G
Sbjct: 2088 CAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-GHPCGQGTCTNVIG 2146
Query: 266 TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
++C C +G+ + + C C NT GSY CTC G+ LR DG C
Sbjct: 2147 GFECACADGFEPGLMMT-CEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMC 2205
Query: 326 RDIDECAGGARPC--GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
RD+DECA G + C G +C+N +G++ C C G+ P G+ C D +EC
Sbjct: 2206 RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRP-LPGSGEGCTDDNEC-------- 2256
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKP--------EQGPA---- 431
Q P+LC G C NT GSF C C +G+ P QGP
Sbjct: 2257 -----HAQ-------PDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Query: 432 ----C----TDDDECELGTCDC------HPAADCINLPGSFQCR--CRDGWRGDGATCED 475
C + + C C P + LPG+ R C G G A D
Sbjct: 2305 LQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG-SGYTAEGRD 2363
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
VDEC C C N+ GSFRC C GY D +C+D+DEC+ P
Sbjct: 2364 VDECRMLAHLC-AHGECINSLGSFRCHCQAGYTPD-------ATATTCLDMDECSQVPKP 2415
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C NT G + C C G+ DGR+C
Sbjct: 2416 C-TFLCKNTKGSFLCSCPRGYLLEEDGRTC 2444
Score = 195 bits (475), Expect = 4e-49
Identities = 135/431 (31%), Positives = 183/431 (42%), Gaps = 60/431 (13%)
Query: 147 PGYEKDSKNHTCV---DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
PG E N V D++EC+ + G+C GDC NT GSF C C PGY + ++IC DI
Sbjct: 1547 PGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDI 1606
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC+ + ++C G C NT G++ C C +C D+ + NG C+N+
Sbjct: 1607 DECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNE 1664
Query: 264 MG----TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
+ C C Q+ + Q C N + G L
Sbjct: 1665 LAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDY---QILCGNQAPGFLTDIHTGKPL- 1720
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
DIDEC C G C N +GS+ C C G + C+D+DEC
Sbjct: 1721 -------DIDECGEIPAICANGICINQIGSFRCECPAGF--NYNSILLACEDVDECGSRE 1771
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC- 438
S Q++ D C N GS+ C+C GY + P G AC +EC
Sbjct: 1772 SPC--------QQNAD-----------CINIPGSYRCKCTRGYKLSP--GGACVGRNECR 1810
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTD 496
E+ H DC++ GS+ C C G++ D C D+DEC G TC N
Sbjct: 1811 EIPNVCSH--GDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG---NGTCKNII 1865
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN-DPTLCENGHCSNTPGGYECDCDVG 555
GS+ CLC G+ G CVD DEC +C GHC NT G + C C G
Sbjct: 1866 GSYNCLCFPGFVVTHNG--------DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDG 1917
Query: 556 FTRAADGRSCL 566
F ADG++C+
Sbjct: 1918 FELTADGKNCV 1928
Score = 168 bits (408), Expect = 5e-41
Identities = 88/250 (35%), Positives = 118/250 (47%), Gaps = 9/250 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC+ P C C+N G F C C GY + TC D++EC C C
Sbjct: 2404 LDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC-QFLC 2461
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G+FTC C PG+ + C D DEC+ C G C NT GSFRCEC G L
Sbjct: 2462 VNTVGAFTCRCPPGFT--QHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTL 2519
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
C+D++EC C +G C+NQ+G Y+C C +G+ Q + +
Sbjct: 2520 VSSGHGCEDVNECDGPHR-CQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPP 2577
Query: 296 RC-QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C SC NT G + C C G+ C+D+DECAG PC C NT G + C C
Sbjct: 2578 TCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPC-SYSCANTPGGFLCGC 2636
Query: 355 TDGLVPSAAG 364
G + G
Sbjct: 2637 PQGYFRAGQG 2646
Score = 136 bits (329), Expect = 2e-31
Identities = 122/399 (30%), Positives = 155/399 (38%), Gaps = 60/399 (15%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD--VNEC--EIVDGVC-G 172
+V+EC A PGLC G C N++G F C C G+ + C D C + G C G
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAG 306
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDE------CADNDALCRGGRCVNTAGSFR 226
D H T C + A ++C CA L G +
Sbjct: 307 DLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGF 366
Query: 227 CECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
G G L P RL+ D GI S G + +GT A
Sbjct: 367 GSNGMGPPLGPARLNPHGSD----ARGIPSLGPGNSNIGT---------ATLNQTIDICR 413
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT 346
RC + TP SY C C G+ G C D+DEC + PC G C N
Sbjct: 414 HFTNLCLNGRC----LPTPSSYRCECNVGYTQDVRG-ECIDVDECT--SSPCHHGDCVNI 466
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
G+Y C C G A + C D+DEC ++S LC G
Sbjct: 467 PGTYHCRCYPGF--QATPTRQACVDVDEC--IVS------------------GGLCHLGR 504
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C NT GSF C C G+ + P+ G C D +EC T + C+N GSF C C+ G+
Sbjct: 505 CVNTEGSFQCVCNAGFELSPD-GKNCVDHNECATSTMCVNGV--CLNEDGSFSCLCKPGF 561
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
G C D+DEC T G C NT+GSFRC C
Sbjct: 562 LLAPGGHYCMDIDECQT--PGICVNGHCTNTEGSFRCQC 598
Score = 134 bits (324), Expect = 8e-31
Identities = 86/241 (35%), Positives = 105/241 (43%), Gaps = 39/241 (16%)
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
ID C C G+C T SY C C G G C D+DEC
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE---CIDVDECTS---------- 455
Query: 388 DELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
P C G C N G++ C+C G+ P + AC D DEC + CH
Sbjct: 456 -------SP-----CHHGDCVNIPGTYHCRCYPGFQATPTR-QACVDVDECIVSGGLCH- 501
Query: 448 AADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
C+N GSFQC C G+ DG C D +EC T+ C C N DGSF CLC
Sbjct: 502 LGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM-C-VNGVCLNEDGSFSCLCKP 559
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G+ G + C+DIDEC P +C NGHC+NT G + C C G DGR C
Sbjct: 560 GFLLAPGG-------HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC 611
Query: 566 L 566
+
Sbjct: 612 V 612
Score = 82.6 bits (195), Expect = 3e-15
Identities = 117/458 (25%), Positives = 154/458 (33%), Gaps = 54/458 (11%)
Query: 136 NLLGG-FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKAD 194
N+ G F C PG+ CV I CG+G C C C G A
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV----VPICRRACGEGFCSQPN---LCTCADGTLAP 110
Query: 195 D--FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM--ELAPDRLSCKDIDECSI 250
S+ C N CRG C+ G CG + + C + C+
Sbjct: 111 SCGVSRGSGCSVSCM-NGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCAC 169
Query: 251 TSGICSNGACENQMGTYQC---VCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
G CE T C V EG C P
Sbjct: 170 VYGFMGP-QCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQ 228
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSAAGA 365
H CR G+ +C+D+DEC C GG C N VGS+ C C G L S+A
Sbjct: 229 PH-PCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 366 KP----TCQDI---DECA-DLIS--TIIMMSVDELQKSVDPQIPELC---GAGSCHNTIG 412
+ C + CA DL T D + +PELC G+
Sbjct: 288 EDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCA 347
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP-AADCINLPGSFQCRCRDGWRGDGA 471
+ P + P ++ LG +P +D +P G
Sbjct: 348 QRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQ 407
Query: 472 TCEDVDECLTN---NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
T D+ TN NG C P T S+RC C+ GY D G C+D+DE
Sbjct: 408 TI-DICRHFTNLCLNGRCLP------TPSSYRCECNVGYTQDVRG--------ECIDVDE 452
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C + P C +G C N PG Y C C GF ++C+
Sbjct: 453 CTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACV 488
Score = 47.6 bits (108), Expect = 1e-04
Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Query: 4 GRCSGPLPTDVLRAVCCCSAL-GKAWGNQRCEPCPKKGTDAYQNLC 48
G+CS P + + CCCS G+ WG+ CE CP++G+ A+Q LC
Sbjct: 2024 GKCSVPKAFNTTKTRCCCSKRPGEGWGDP-CELCPQEGSAAFQELC 2068
Score = 46.0 bits (104), Expect = 4e-04
Identities = 20/35 (57%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V RA CCC G+ WG RCE CP GT AY+ LC
Sbjct: 2319 VTRAECCCGG-GRGWG-PRCELCPLPGTSAYRKLC 2351
Score = 36.3 bits (80), Expect = 0.29
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C LP VCCCS +G WG + CE CP + + +LC
Sbjct: 926 CGVTLPGKYRMDVCCCS-IGAVWGVE-CEACPDPESLEFASLC 966
>AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 1 protein.
Length = 2809
Score = 436 bits (1075), Expect = e-122
Identities = 196/449 (43%), Positives = 252/449 (56%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC FPGLC HG CRN +G F C C G+ D++ C D++EC I +CG G C
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY++ K C+D+DECA + LCRGG C NT GS++C+C G EL
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+C+DIDECS++ G+C +G C N +G +QC C G+ + +
Sbjct: 1106 AKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGG 1165
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C C+NT GSY C+C +G+ L DGR+C D+DEC R C G C N G + C C D
Sbjct: 1166 CDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYD 1225
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A TC D+DEC DL P +C G C NT GSFVC
Sbjct: 1226 GFM--ATPDMRTCVDVDEC-DL-------------------NPHICLHGDCENTKGSFVC 1263
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GY V+ + C+D DECE+G +C A C+N+PGSF CRC GW GDG C D+
Sbjct: 1264 HCQLGYMVR-KGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDL 1322
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC++ C PR C N GS+RC C G+ GDG + C D DECA + LC
Sbjct: 1323 DECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDG---------FFCEDRDECAENVDLC 1373
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+NG C N PGGY C+C++GF D R+C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRAC 1402
Score = 299 bits (734), Expect = 2e-80
Identities = 162/454 (35%), Positives = 214/454 (47%), Gaps = 42/454 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+V+ECA P LC G C N G + C C PG+E +K C D++EC + DG+C G C
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQC 1129
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G+F C C G+++ + CVDI+EC + C C+NT GS+RC CG G L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC-DVHCINTEGSYRCSCGQGYSLM 1188
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
PD +C D+DEC +C G C N G ++C+C +G+ +
Sbjct: 1189 PDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHI 1248
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTC 354
C H C NT GS+ C C+ G+ +R C D+DEC G C C N GS++C C
Sbjct: 1249 CLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRC 1308
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G V G C D+DEC + P+ G C N GS+
Sbjct: 1309 LPGWV----GDGFECHDLDECV------------SQEHRCSPR-------GDCLNVPGSY 1345
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C C G++ G C D DEC D C+N PG ++C C G+ D
Sbjct: 1346 RCTCRQGFA---GDGFFCEDRDEC-AENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRA 1401
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C+DVDEC G +C N G FRC+C+ GY+ D G +C DI+ECA D
Sbjct: 1402 CQDVDECA--QGNLCAFGSCENLPGMFRCICNGGYELDRGG-------GNCTDINECA-D 1451
Query: 533 PTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P C NG C NTPG Y C C F G C+
Sbjct: 1452 PVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Score = 259 bits (634), Expect = 2e-68
Identities = 181/571 (31%), Positives = 248/571 (43%), Gaps = 70/571 (12%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
+G CS + V RA CCCS LG+AWGN CE CP T Y+ LC G PN+
Sbjct: 1502 SGISCSAEIGVGVTRASCCCS-LGRAWGNP-CELCPMANTTEYRTLCPG-GEGFQPNR-- 1556
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNE 121
+T I + DE + G G + +++E
Sbjct: 1557 ------ITVILEDI--DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDE 1608
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C-EIVDGVCGDGDCHN 178
C+ +CG G C N LG +TC C Y + + + C+D+ + C +G C + N
Sbjct: 1609 CSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFN 1668
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
C C +++ C + C + C N A F + G L
Sbjct: 1669 VTRKMCC-CSYNI-GQAWNRPC---EACPTPISPDYQILCGNQAPGFLTDIHTGKPL--- 1720
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
DIDEC IC+NG C NQ+G+++C C G+ +++ CQ
Sbjct: 1721 -----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 299 HS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
+ C+N PGSY C C G+ L + G +C +EC C G C +T GSY C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKL-SPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHR 1834
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G SA + C DIDEC D Q P CG G+C N IGS+ C
Sbjct: 1835 GFQASAD--QTLCMDIDEC-------------------DRQ-P--CGNGTCKNIIGSYNC 1870
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCE 474
C G+ V C D DEC C+N GSF C C+DG+ DG C
Sbjct: 1871 LCFPGFVVT--HNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCV 1928
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D +ECL+ G C P TC N +GSFRC+C G++ C+DIDEC+ +P
Sbjct: 1929 DTNECLSLAGTCLP-GTCQNLEGSFRCICPPGFQVQSD---------HCIDIDECSEEPN 1978
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
LC G C+N+PG ++C C GF + +G C
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 258 bits (633), Expect = 3e-68
Identities = 163/475 (34%), Positives = 220/475 (46%), Gaps = 73/475 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGD 175
++++EC P +C +G C N +G F C+C G+ +S C DV+EC + C + D
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C GYK CV +EC + +C G C++T GS+ C C G +
Sbjct: 1780 CINIPGSYRCKCTRGYKLSP-GGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D+ C DIDEC C NG C+N +G+Y C+C G+ +
Sbjct: 1839 SADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+ C+NT GS+HC C++G+ L ADG++C D +EC A C G C+N GS+ C C
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCIC 1956
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + C DIDEC+ + P LC G+C N+ GSF
Sbjct: 1957 PPGFQVQS----DHCIDIDECS--------------------EEPNLCLFGTCTNSPGSF 1992
Query: 415 VCQCPDGYSVKPEQGPACTDDDE--C----ELGTCDCHPAAD-------CINLPG----- 456
C CP G+ V + G C D + C E G C A + C PG
Sbjct: 1993 QCLCPPGF-VLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGD 2051
Query: 457 -----------SFQCRCRDGW---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+FQ C G G + EDV+EC N G C C NTDGSFRC
Sbjct: 2052 PCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVC-TNGVCVNTDGSFRCE 2110
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECA-NDPTLCENGHCSNTPGGYECDCDVGF 556
C GY D G+ +CVD DEC+ P C G C+N GG+EC C GF
Sbjct: 2111 CPFGYSLDFTGI-------NCVDTDECSVGHP--CGQGTCTNVIGGFECACADGF 2156
Score = 258 bits (631), Expect = 5e-68
Identities = 169/524 (32%), Positives = 227/524 (43%), Gaps = 36/524 (6%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRC-EPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
GGRC+G L R CCC G+ W E CP +G++ +Q LC LLP +
Sbjct: 301 GGRCAGDLAGHYTRRQCCCDR-GRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGL 359
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGE-NXXXXXXXXXXXXXXXXXXXXXXXXQMEVN 120
P +G NG G N ++
Sbjct: 360 FP---------GLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTID 410
Query: 121 ECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTE 180
C F LC +GRC + C+C GY +D + C+DV+EC C GDC N
Sbjct: 411 ICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDEC--TSSPCHHGDCVNIP 467
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
G++ C C PG++A + CVD+DEC + LC GRCVNT GSF+C C G EL+PD
Sbjct: 468 GTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+C D +EC+ TS +C NG C N+ G++ C+C G+ + +
Sbjct: 528 NCVDHNECA-TSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH 586
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCR----NTVGSYTCTCTD 356
C NT GS+ C C G + DGR C D + G C TV C C +
Sbjct: 587 CTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCAN 646
Query: 357 GLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
P +P CQ + E L S+ + ++ D + PE+C G C N
Sbjct: 647 ---PDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR 702
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GD 469
GS+ C C GY G CTD DEC L + C C N PGS+ C C G+ D
Sbjct: 703 GSYRCVCNLGYEA-GASGKDCTDVDECALNSLLCDNGW-CQNSPGSYSCSCPPGFHFWQD 760
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
C+DVDECL++ C C N GS+ C C G + D G
Sbjct: 761 TEICKDVDECLSS--PC-VSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 251 bits (614), Expect = 6e-66
Identities = 155/466 (33%), Positives = 208/466 (44%), Gaps = 32/466 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC P +C G C N+ GG C C+ G+ TCVDV+EC++ +C GDC
Sbjct: 1196 DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCE 1255
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC+ GY + C D+DEC C C+N GSF C C G
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--V 1313
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D C D+DEC CS G C N G+Y+C C +G+A
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL- 1372
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C + C+N PG Y C C G+ D R+C+D+DECA G C G C N G + C C
Sbjct: 1373 -CDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQG-NLCAFGSCENLPGMFRCIC 1430
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTI--IMMSVDELQKSVDPQIPEL--CGAGSCHNT 410
G G C DI+ECAD ++ I + ++ PQ EL G G
Sbjct: 1431 NGGYELDRGGG--NCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTR 1488
Query: 411 IGSFVCQCPD----GYSVKPEQGPACTDDD-ECELGTCDCHPAADC-INLPGSFQCRC-- 462
G+ + D G S E G T C LG +P C + ++ C
Sbjct: 1489 AGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPG 1548
Query: 463 RDGWRGDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
+G++ + T ED+DEC G C C NT GSF+C C GY +
Sbjct: 1549 GEGFQPNRITVILEDIDECQELPGLCQ-GGDCVNTFGSFQCECPPGYHLSEH-------T 1600
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DIDEC+ ++C G C NT G Y C C + + G +C+
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCM 1646
Score = 247 bits (604), Expect = 9e-65
Identities = 156/461 (33%), Positives = 199/461 (43%), Gaps = 31/461 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNECA PG+C +G C N G F C+C GY D CVD +EC V CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCT 2142
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G F C C G++ C DIDEC+ N LC RC NT GS+ C C G L
Sbjct: 2143 NVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLC-AFRCHNTEGSYLCTCPAGYTLRE 2200
Query: 238 DRLSCKDIDECSITSGIC-SNG-ACENQMGTYQCVCDEGYAQSTVKSHX-XXXXXXXXXX 294
D C+D+DEC+ C + G C+N +GT+ CVC G
Sbjct: 2201 DGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQP 2260
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN-TVGSYTC 352
C + CVNT GS+ C C EG+ C DI + A CR+ + S
Sbjct: 2261 DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVL-QTMCRSLSSSSEAV 2319
Query: 353 TCTDGLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
T + G P C+ L + + + LC G C
Sbjct: 2320 TRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGEC 2379
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW- 466
N++GSF C C GY+ C D DEC C C N GSF C C G+
Sbjct: 2380 INSLGSFRCHCQAGYT-PDATATTCLDMDECSQVPKPC--TFLCKNTKGSFLCSCPRGYL 2436
Query: 467 -RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
DG TC+D+DEC + C + C NT G+F C C G+ +C D
Sbjct: 2437 LEEDGRTCKDLDECTSRQHNC--QFLCVNTVGAFTCRCPPGFTQHH---------QACFD 2485
Query: 526 IDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DEC+ P C +GHC NTPG + C+C GFT + G C
Sbjct: 2486 NDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGC 2526
Score = 243 bits (594), Expect = 2e-63
Identities = 157/448 (35%), Positives = 205/448 (45%), Gaps = 74/448 (16%)
Query: 157 TCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI-----------DE 205
TC DVNECE GVC +G C NT GSF C C G D ++CVD+ DE
Sbjct: 866 TCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDE 925
Query: 206 CADN-DALCRGGRCVNTAGSF---RCE-------------CGHGMELAP-DRLS----CK 243
C R C + G+ CE C G+ A D LS K
Sbjct: 926 CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYK 985
Query: 244 DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHSCV 302
D++EC + G+C++G C N +G++ C C G+A + + C Q +CV
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 303 NTPGSYHCTCREGWHLR-ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
NTPGS+ C C G+ ++C D+DECA C GG C NT GSY C C G +
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
A G C+DIDEC S+ + LC G C N IG+F C C G
Sbjct: 1106 AKGT--ACEDIDEC----------SLSD----------GLCPHGQCVNVIGAFQCSCHAG 1143
Query: 422 YSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVD 477
+ P++ C D +EC + G CD H CIN GS++C C G+ DG C DVD
Sbjct: 1144 FQSTPDR-QGCVDINECRVQNGGCDVH----CINTEGSYRCSCGQGYSLMPDGRACADVD 1198
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC N C + C N G RCLC G+ +RT CVD+DEC +P +C
Sbjct: 1199 ECEENPRVC-DQGHCTNMPGGHRCLCYDGFMATP-DMRT------CVDVDECDLNPHICL 1250
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
+G C NT G + C C +G+ C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGC 1278
Score = 239 bits (586), Expect = 1e-62
Identities = 169/500 (33%), Positives = 218/500 (43%), Gaps = 87/500 (17%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC + P C HG C N+ G + C C+PG++ CVDV+EC + G+C G C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NTEGSF C C G++ K CVD +ECA + +C G C+N GSF C C G LA
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATS-TMCVNGVCLNEDGSFSCLCKPGFLLA 564
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTY--QC-----------VCDEGYAQST---- 279
P C DIDEC T GIC NG C N G++ QC VC + + +ST
Sbjct: 565 PGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 280 --------------VKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
KS CQ + C G + DGR
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 326 RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
DI+ECA C G C N GSY C C G A+G C D+DECA
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKD--CTDVDECA--------- 729
Query: 386 SVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
++ L LC G C N+ GS+ C CP G+ + C D DEC C
Sbjct: 730 -LNSL----------LCDNGWCQNSPGSYSCSCPPGFHFWQDT-EICKDVDECLSSPC-- 775
Query: 446 HPAADCINLPGSFQCRCRDGWRGD--GATCED---------VDE--CLTNNGGCHPRATC 492
+ C NL GS+ C+C G R D G C D + E C N G R+ C
Sbjct: 776 -VSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSEC 834
Query: 493 ANTDGSF------RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG 546
T G+ RC D G+ T +C D++EC + P +C NG C NT G
Sbjct: 835 CATLGAAWGSPCERCEIDPAC-ARGFARMTGV---TCDDVNECESFPGVCPNGRCVNTAG 890
Query: 547 GYECDCDVGFTRAADGRSCL 566
+ C+C G A GR C+
Sbjct: 891 SFRCECPEGLMLDASGRLCV 910
Score = 239 bits (584), Expect = 2e-62
Identities = 154/457 (33%), Positives = 206/457 (45%), Gaps = 63/457 (13%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG-D 175
+++EC+ P LC RC N G + C C GY C DV+EC C G +
Sbjct: 2166 DIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGME 2224
Query: 176 CHNTEGSFTCHCRPGYKADDFS-KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C N G+F C C PG + S + C D +EC LC GRCVNTAGSFRC+C G +
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 235 LAPDRLSCKDIDE----CSITSGICSNGACENQMGTY-QCVCDEGYAQSTVKSHXXXXXX 289
+P C DI + + +C + + ++ T +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGP---------- 2334
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
RC+ + +Y C G A+GR D+DEC A C G+C N++GS
Sbjct: 2335 ------RCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLCAHGECINSLGS 2385
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
+ C C G P A TC D+DEC+ Q+P+ C C N
Sbjct: 2386 FRCHCQAGYTPDATAT--TCLDMDECS--------------------QVPKPC-TFLCKN 2422
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
T GSF+C CP GY ++ E G C D DEC +C C+N G+F CRC G+
Sbjct: 2423 TKGSFLCSCPRGYLLE-EDGRTCKDLDECTSRQHNCQFL--CVNTVGAFTCRCPPGFTQH 2479
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
C D DEC G C C NT GSFRC C G+ V + C D++EC
Sbjct: 2480 HQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGF-------TLVSSGHGCEDVNEC 2532
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ P C++G C N GGY C C GFT+ + C+
Sbjct: 2533 -DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCV 2567
Score = 231 bits (564), Expect = 7e-60
Identities = 159/484 (32%), Positives = 212/484 (43%), Gaps = 73/484 (15%)
Query: 118 EVNECAAFPGLCGHGR---CRNLLGGFTCDCFPGYEK-DSKNHTCVDVNECEIVDGVCGD 173
+V+ECA C H R C+NL+G F C C PG C D NEC +C +
Sbjct: 2207 DVDECADGQQDC-HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVN 2265
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDE--CADN--DALCRGGRCVNTAGS-FRCE 228
G C NT GSF C C G++ C DI + C +CR + A + C
Sbjct: 2266 GRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECC 2325
Query: 229 CGHGM------ELAP------DRLSC----------KDIDECSITSGICSNGACENQMGT 266
CG G EL P R C +D+DEC + + +C++G C N +G+
Sbjct: 2326 CGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGS 2385
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR 326
++C C GY + C C NT GS+ C+C G+ L DGR+C+
Sbjct: 2386 FRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
D+DEC C C NTVG++TC C G C D DEC+
Sbjct: 2446 DLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFTQH----HQACFDNDECSAQ-------- 2492
Query: 387 VDELQKSVDPQIPELCGA-GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
P CGA G CHNT GSF C+C G+++ G C D +EC+ G C
Sbjct: 2493 ------------PGPCGAHGHCHNTPGSFRCECHQGFTLV-SSGHGCEDVNECD-GPHRC 2538
Query: 446 HPAADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N G ++C C G+ A C D +EC + C A+C NT G FRC+C
Sbjct: 2539 QHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGS-ASCRNTLGGFRCVC 2595
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGR 563
+G+ D + C D+DECA C C+NTPGG+ C C G+ RA G
Sbjct: 2596 PSGFDFDQ-------ALGGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQGH 2647
Query: 564 SCLG 567
G
Sbjct: 2648 CVSG 2651
Score = 230 bits (563), Expect = 9e-60
Identities = 151/465 (32%), Positives = 209/465 (44%), Gaps = 52/465 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C C GYE + C DV+EC + +C +G C
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQ 741
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N+ GS++C C PG+ ++IC D+DEC + C G C N AGS+ C+CG G L P
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDP 799
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
C D T G C E++ C+ ++++S C
Sbjct: 800 SGTFCLD-----STKGTCWLKIQESR-------CEVNLQGASLRSE-CCATLGAAWGSPC 846
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+ C P C G+ R G +C D++EC C G+C NT GS+ C C +G
Sbjct: 847 ER-CEIDP-----ACARGF-ARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEG 899
Query: 358 LVPSAAGAKPTCQDI-----------DECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
L+ A+G C D+ DEC + M D S+ C A
Sbjct: 900 LMLDASGR--LCVDVRLEPCFLRWDEDECGVTLPGKYRM--DVCCCSIGAVWGVECEACP 955
Query: 407 CHNTIGSFVCQCPDGYSVKPEQ----GPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
++ F CP G P D +EC++ C C N GSF C C
Sbjct: 956 DPESL-EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCAC 1013
Query: 463 RDGWRGDG--ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ D C D+DEC + C + TC NT GSF C C GY+ G+ L +
Sbjct: 1014 AGGFALDAQERNCTDIDECRISPDLC-GQGTCVNTPGSFECECFPGYE-SGFML-----M 1066
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+C+D+DECA DP LC G C+NT G Y+C C G A G +C
Sbjct: 1067 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 230 bits (562), Expect = 1e-59
Identities = 165/510 (32%), Positives = 215/510 (42%), Gaps = 94/510 (18%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C--EIVDGVCG 172
++++EC+ P LC G C N G F C C PG+ H C D + C G C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCS 2027
Query: 173 DGDCHN-TEGSFTCHCRPGYKADD------------FSKIC--------------VDIDE 205
N T+ C RPG D F ++C D++E
Sbjct: 2028 VPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNE 2087
Query: 206 CADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMG 265
CA+N +C G CVNT GSFRCEC G L ++C D DECS+ C G C N +G
Sbjct: 2088 CAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-GHPCGQGTCTNVIG 2146
Query: 266 TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
++C C +G+ + + C C NT GSY CTC G+ LR DG C
Sbjct: 2147 GFECACADGFEPGLMMT-CEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMC 2205
Query: 326 RDIDECAGGARPC--GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
RD+DECA G + C G +C+N +G++ C C G+ P G+ C D +EC
Sbjct: 2206 RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRP-LPGSGEGCTDDNEC-------- 2256
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKP--------EQGPA---- 431
Q P+LC G C NT GSF C C +G+ P QGP
Sbjct: 2257 -----HAQ-------PDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Query: 432 ----C----TDDDECELGTCDC------HPAADCINLPGSFQCR--CRDGWRGDGATCED 475
C + + C C P + LPG+ R C G G A D
Sbjct: 2305 LQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG-SGYTAEGRD 2363
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
VDEC C C N+ GSFRC C GY D +C+D+DEC+ P
Sbjct: 2364 VDECRMLAHLC-AHGECINSLGSFRCHCQAGYTPD-------ATATTCLDMDECSQVPKP 2415
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C NT G + C C G+ DGR+C
Sbjct: 2416 C-TFLCKNTKGSFLCSCPRGYLLEEDGRTC 2444
Score = 195 bits (475), Expect = 4e-49
Identities = 135/431 (31%), Positives = 183/431 (42%), Gaps = 60/431 (13%)
Query: 147 PGYEKDSKNHTCV---DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
PG E N V D++EC+ + G+C GDC NT GSF C C PGY + ++IC DI
Sbjct: 1547 PGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDI 1606
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC+ + ++C G C NT G++ C C +C D+ + NG C+N+
Sbjct: 1607 DECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNE 1664
Query: 264 MG----TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
+ C C Q+ + Q C N + G L
Sbjct: 1665 LAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDY---QILCGNQAPGFLTDIHTGKPL- 1720
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
DIDEC C G C N +GS+ C C G + C+D+DEC
Sbjct: 1721 -------DIDECGEIPAICANGICINQIGSFRCECPAGF--NYNSILLACEDVDECGSRE 1771
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC- 438
S Q++ D C N GS+ C+C GY + P G AC +EC
Sbjct: 1772 SPC--------QQNAD-----------CINIPGSYRCKCTRGYKLSP--GGACVGRNECR 1810
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTD 496
E+ H DC++ GS+ C C G++ D C D+DEC G TC N
Sbjct: 1811 EIPNVCSH--GDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG---NGTCKNII 1865
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN-DPTLCENGHCSNTPGGYECDCDVG 555
GS+ CLC G+ G CVD DEC +C GHC NT G + C C G
Sbjct: 1866 GSYNCLCFPGFVVTHNG--------DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDG 1917
Query: 556 FTRAADGRSCL 566
F ADG++C+
Sbjct: 1918 FELTADGKNCV 1928
Score = 168 bits (408), Expect = 5e-41
Identities = 88/250 (35%), Positives = 118/250 (47%), Gaps = 9/250 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC+ P C C+N G F C C GY + TC D++EC C C
Sbjct: 2404 LDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC-QFLC 2461
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G+FTC C PG+ + C D DEC+ C G C NT GSFRCEC G L
Sbjct: 2462 VNTVGAFTCRCPPGFT--QHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTL 2519
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
C+D++EC C +G C+NQ+G Y+C C +G+ Q + +
Sbjct: 2520 VSSGHGCEDVNECDGPHR-CQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPP 2577
Query: 296 RC-QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C SC NT G + C C G+ C+D+DECAG PC C NT G + C C
Sbjct: 2578 TCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPC-SYSCANTPGGFLCGC 2636
Query: 355 TDGLVPSAAG 364
G + G
Sbjct: 2637 PQGYFRAGQG 2646
Score = 136 bits (329), Expect = 2e-31
Identities = 122/399 (30%), Positives = 155/399 (38%), Gaps = 60/399 (15%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD--VNEC--EIVDGVC-G 172
+V+EC A PGLC G C N++G F C C G+ + C D C + G C G
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAG 306
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDE------CADNDALCRGGRCVNTAGSFR 226
D H T C + A ++C CA L G +
Sbjct: 307 DLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGF 366
Query: 227 CECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
G G L P RL+ D GI S G + +GT A
Sbjct: 367 GSNGMGPPLGPARLNPHGSD----ARGIPSLGPGNSNIGT---------ATLNQTIDICR 413
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT 346
RC + TP SY C C G+ G C D+DEC + PC G C N
Sbjct: 414 HFTNLCLNGRC----LPTPSSYRCECNVGYTQDVRG-ECIDVDECT--SSPCHHGDCVNI 466
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
G+Y C C G A + C D+DEC ++S LC G
Sbjct: 467 PGTYHCRCYPGF--QATPTRQACVDVDEC--IVS------------------GGLCHLGR 504
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C NT GSF C C G+ + P+ G C D +EC T + C+N GSF C C+ G+
Sbjct: 505 CVNTEGSFQCVCNAGFELSPD-GKNCVDHNECATSTMCVNGV--CLNEDGSFSCLCKPGF 561
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
G C D+DEC T G C NT+GSFRC C
Sbjct: 562 LLAPGGHYCMDIDECQT--PGICVNGHCTNTEGSFRCQC 598
Score = 134 bits (324), Expect = 8e-31
Identities = 86/241 (35%), Positives = 105/241 (43%), Gaps = 39/241 (16%)
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
ID C C G+C T SY C C G G C D+DEC
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE---CIDVDECTS---------- 455
Query: 388 DELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
P C G C N G++ C+C G+ P + AC D DEC + CH
Sbjct: 456 -------SP-----CHHGDCVNIPGTYHCRCYPGFQATPTR-QACVDVDECIVSGGLCH- 501
Query: 448 AADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
C+N GSFQC C G+ DG C D +EC T+ C C N DGSF CLC
Sbjct: 502 LGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM-C-VNGVCLNEDGSFSCLCKP 559
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G+ G + C+DIDEC P +C NGHC+NT G + C C G DGR C
Sbjct: 560 GFLLAPGG-------HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC 611
Query: 566 L 566
+
Sbjct: 612 V 612
Score = 82.6 bits (195), Expect = 3e-15
Identities = 117/458 (25%), Positives = 154/458 (33%), Gaps = 54/458 (11%)
Query: 136 NLLGG-FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKAD 194
N+ G F C PG+ CV I CG+G C C C G A
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV----VPICRRACGEGFCSQPN---LCTCADGTLAP 110
Query: 195 D--FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM--ELAPDRLSCKDIDECSI 250
S+ C N CRG C+ G CG + + C + C+
Sbjct: 111 SCGVSRGSGCSVSCM-NGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCAC 169
Query: 251 TSGICSNGACENQMGTYQC---VCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
G CE T C V EG C P
Sbjct: 170 VYGFMGP-QCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQ 228
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSAAGA 365
H CR G+ +C+D+DEC C GG C N VGS+ C C G L S+A
Sbjct: 229 PH-PCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 366 KP----TCQDI---DECA-DLIS--TIIMMSVDELQKSVDPQIPELC---GAGSCHNTIG 412
+ C + CA DL T D + +PELC G+
Sbjct: 288 EDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCA 347
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP-AADCINLPGSFQCRCRDGWRGDGA 471
+ P + P ++ LG +P +D +P G
Sbjct: 348 QRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQ 407
Query: 472 TCEDVDECLTN---NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
T D+ TN NG C P T S+RC C+ GY D G C+D+DE
Sbjct: 408 TI-DICRHFTNLCLNGRCLP------TPSSYRCECNVGYTQDVRG--------ECIDVDE 452
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C + P C +G C N PG Y C C GF ++C+
Sbjct: 453 CTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACV 488
Score = 47.6 bits (108), Expect = 1e-04
Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Query: 4 GRCSGPLPTDVLRAVCCCSAL-GKAWGNQRCEPCPKKGTDAYQNLC 48
G+CS P + + CCCS G+ WG+ CE CP++G+ A+Q LC
Sbjct: 2024 GKCSVPKAFNTTKTRCCCSKRPGEGWGDP-CELCPQEGSAAFQELC 2068
Score = 46.0 bits (104), Expect = 4e-04
Identities = 20/35 (57%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V RA CCC G+ WG RCE CP GT AY+ LC
Sbjct: 2319 VTRAECCCGG-GRGWG-PRCELCPLPGTSAYRKLC 2351
Score = 36.3 bits (80), Expect = 0.29
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C LP VCCCS +G WG + CE CP + + +LC
Sbjct: 926 CGVTLPGKYRMDVCCCS-IGAVWGVE-CEACPDPESLEFASLC 966
>AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 436 bits (1075), Expect = e-122
Identities = 196/449 (43%), Positives = 252/449 (56%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC FPGLC HG CRN +G F C C G+ D++ C D++EC I +CG G C
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY++ K C+D+DECA + LCRGG C NT GS++C+C G EL
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+C+DIDECS++ G+C +G C N +G +QC C G+ + +
Sbjct: 1106 AKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGG 1165
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C C+NT GSY C+C +G+ L DGR+C D+DEC R C G C N G + C C D
Sbjct: 1166 CDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYD 1225
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A TC D+DEC DL P +C G C NT GSFVC
Sbjct: 1226 GFM--ATPDMRTCVDVDEC-DL-------------------NPHICLHGDCENTKGSFVC 1263
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GY V+ + C+D DECE+G +C A C+N+PGSF CRC GW GDG C D+
Sbjct: 1264 HCQLGYMVR-KGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDL 1322
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC++ C PR C N GS+RC C G+ GDG + C D DECA + LC
Sbjct: 1323 DECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDG---------FFCEDRDECAENVDLC 1373
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+NG C N PGGY C+C++GF D R+C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRAC 1402
Score = 299 bits (734), Expect = 2e-80
Identities = 162/454 (35%), Positives = 214/454 (47%), Gaps = 42/454 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+V+ECA P LC G C N G + C C PG+E +K C D++EC + DG+C G C
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQC 1129
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G+F C C G+++ + CVDI+EC + C C+NT GS+RC CG G L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC-DVHCINTEGSYRCSCGQGYSLM 1188
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
PD +C D+DEC +C G C N G ++C+C +G+ +
Sbjct: 1189 PDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHI 1248
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTC 354
C H C NT GS+ C C+ G+ +R C D+DEC G C C N GS++C C
Sbjct: 1249 CLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRC 1308
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G V G C D+DEC + P+ G C N GS+
Sbjct: 1309 LPGWV----GDGFECHDLDECV------------SQEHRCSPR-------GDCLNVPGSY 1345
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C C G++ G C D DEC D C+N PG ++C C G+ D
Sbjct: 1346 RCTCRQGFA---GDGFFCEDRDEC-AENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRA 1401
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C+DVDEC G +C N G FRC+C+ GY+ D G +C DI+ECA D
Sbjct: 1402 CQDVDECA--QGNLCAFGSCENLPGMFRCICNGGYELDRGG-------GNCTDINECA-D 1451
Query: 533 PTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P C NG C NTPG Y C C F G C+
Sbjct: 1452 PVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Score = 259 bits (634), Expect = 2e-68
Identities = 181/571 (31%), Positives = 248/571 (43%), Gaps = 70/571 (12%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
+G CS + V RA CCCS LG+AWGN CE CP T Y+ LC G PN+
Sbjct: 1502 SGISCSAEIGVGVTRASCCCS-LGRAWGNP-CELCPMANTTEYRTLCPG-GEGFQPNR-- 1556
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNE 121
+T I + DE + G G + +++E
Sbjct: 1557 ------ITVILEDI--DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDE 1608
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C-EIVDGVCGDGDCHN 178
C+ +CG G C N LG +TC C Y + + + C+D+ + C +G C + N
Sbjct: 1609 CSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFN 1668
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
C C +++ C + C + C N A F + G L
Sbjct: 1669 VTRKMCC-CSYNI-GQAWNRPC---EACPTPISPDYQILCGNQAPGFLTDIHTGKPL--- 1720
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
DIDEC IC+NG C NQ+G+++C C G+ +++ CQ
Sbjct: 1721 -----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 299 HS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
+ C+N PGSY C C G+ L + G +C +EC C G C +T GSY C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKL-SPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHR 1834
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G SA + C DIDEC D Q P CG G+C N IGS+ C
Sbjct: 1835 GFQASAD--QTLCMDIDEC-------------------DRQ-P--CGNGTCKNIIGSYNC 1870
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCE 474
C G+ V C D DEC C+N GSF C C+DG+ DG C
Sbjct: 1871 LCFPGFVVT--HNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCV 1928
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D +ECL+ G C P TC N +GSFRC+C G++ C+DIDEC+ +P
Sbjct: 1929 DTNECLSLAGTCLP-GTCQNLEGSFRCICPPGFQVQSD---------HCIDIDECSEEPN 1978
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
LC G C+N+PG ++C C GF + +G C
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 258 bits (633), Expect = 3e-68
Identities = 163/475 (34%), Positives = 220/475 (46%), Gaps = 73/475 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGD 175
++++EC P +C +G C N +G F C+C G+ +S C DV+EC + C + D
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C GYK CV +EC + +C G C++T GS+ C C G +
Sbjct: 1780 CINIPGSYRCKCTRGYKLSP-GGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D+ C DIDEC C NG C+N +G+Y C+C G+ +
Sbjct: 1839 SADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+ C+NT GS+HC C++G+ L ADG++C D +EC A C G C+N GS+ C C
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCIC 1956
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + C DIDEC+ + P LC G+C N+ GSF
Sbjct: 1957 PPGFQVQS----DHCIDIDECS--------------------EEPNLCLFGTCTNSPGSF 1992
Query: 415 VCQCPDGYSVKPEQGPACTDDDE--C----ELGTCDCHPAAD-------CINLPG----- 456
C CP G+ V + G C D + C E G C A + C PG
Sbjct: 1993 QCLCPPGF-VLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGD 2051
Query: 457 -----------SFQCRCRDGW---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+FQ C G G + EDV+EC N G C C NTDGSFRC
Sbjct: 2052 PCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVC-TNGVCVNTDGSFRCE 2110
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECA-NDPTLCENGHCSNTPGGYECDCDVGF 556
C GY D G+ +CVD DEC+ P C G C+N GG+EC C GF
Sbjct: 2111 CPFGYSLDFTGI-------NCVDTDECSVGHP--CGQGTCTNVIGGFECACADGF 2156
Score = 258 bits (631), Expect = 5e-68
Identities = 169/524 (32%), Positives = 227/524 (43%), Gaps = 36/524 (6%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRC-EPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
GGRC+G L R CCC G+ W E CP +G++ +Q LC LLP +
Sbjct: 301 GGRCAGDLAGHYTRRQCCCDR-GRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGL 359
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGE-NXXXXXXXXXXXXXXXXXXXXXXXXQMEVN 120
P +G NG G N ++
Sbjct: 360 FP---------GLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTID 410
Query: 121 ECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTE 180
C F LC +GRC + C+C GY +D + C+DV+EC C GDC N
Sbjct: 411 ICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDEC--TSSPCHHGDCVNIP 467
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
G++ C C PG++A + CVD+DEC + LC GRCVNT GSF+C C G EL+PD
Sbjct: 468 GTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+C D +EC+ TS +C NG C N+ G++ C+C G+ + +
Sbjct: 528 NCVDHNECA-TSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH 586
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCR----NTVGSYTCTCTD 356
C NT GS+ C C G + DGR C D + G C TV C C +
Sbjct: 587 CTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCAN 646
Query: 357 GLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
P +P CQ + E L S+ + ++ D + PE+C G C N
Sbjct: 647 ---PDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR 702
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GD 469
GS+ C C GY G CTD DEC L + C C N PGS+ C C G+ D
Sbjct: 703 GSYRCVCNLGYEA-GASGKDCTDVDECALNSLLCDNGW-CQNSPGSYSCSCPPGFHFWQD 760
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
C+DVDECL++ C C N GS+ C C G + D G
Sbjct: 761 TEICKDVDECLSS--PC-VSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 251 bits (614), Expect = 6e-66
Identities = 155/466 (33%), Positives = 208/466 (44%), Gaps = 32/466 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC P +C G C N+ GG C C+ G+ TCVDV+EC++ +C GDC
Sbjct: 1196 DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCE 1255
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC+ GY + C D+DEC C C+N GSF C C G
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--V 1313
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D C D+DEC CS G C N G+Y+C C +G+A
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL- 1372
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C + C+N PG Y C C G+ D R+C+D+DECA G C G C N G + C C
Sbjct: 1373 -CDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQG-NLCAFGSCENLPGMFRCIC 1430
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTI--IMMSVDELQKSVDPQIPEL--CGAGSCHNT 410
G G C DI+ECAD ++ I + ++ PQ EL G G
Sbjct: 1431 NGGYELDRGGG--NCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTR 1488
Query: 411 IGSFVCQCPD----GYSVKPEQGPACTDDD-ECELGTCDCHPAADC-INLPGSFQCRC-- 462
G+ + D G S E G T C LG +P C + ++ C
Sbjct: 1489 AGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPG 1548
Query: 463 RDGWRGDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
+G++ + T ED+DEC G C C NT GSF+C C GY +
Sbjct: 1549 GEGFQPNRITVILEDIDECQELPGLCQ-GGDCVNTFGSFQCECPPGYHLSEH-------T 1600
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DIDEC+ ++C G C NT G Y C C + + G +C+
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCM 1646
Score = 247 bits (604), Expect = 9e-65
Identities = 156/461 (33%), Positives = 199/461 (43%), Gaps = 31/461 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNECA PG+C +G C N G F C+C GY D CVD +EC V CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCT 2142
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G F C C G++ C DIDEC+ N LC RC NT GS+ C C G L
Sbjct: 2143 NVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLC-AFRCHNTEGSYLCTCPAGYTLRE 2200
Query: 238 DRLSCKDIDECSITSGIC-SNG-ACENQMGTYQCVCDEGYAQSTVKSHX-XXXXXXXXXX 294
D C+D+DEC+ C + G C+N +GT+ CVC G
Sbjct: 2201 DGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQP 2260
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN-TVGSYTC 352
C + CVNT GS+ C C EG+ C DI + A CR+ + S
Sbjct: 2261 DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVL-QTMCRSLSSSSEAV 2319
Query: 353 TCTDGLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
T + G P C+ L + + + LC G C
Sbjct: 2320 TRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGEC 2379
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW- 466
N++GSF C C GY+ C D DEC C C N GSF C C G+
Sbjct: 2380 INSLGSFRCHCQAGYT-PDATATTCLDMDECSQVPKPC--TFLCKNTKGSFLCSCPRGYL 2436
Query: 467 -RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
DG TC+D+DEC + C + C NT G+F C C G+ +C D
Sbjct: 2437 LEEDGRTCKDLDECTSRQHNC--QFLCVNTVGAFTCRCPPGFTQHH---------QACFD 2485
Query: 526 IDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DEC+ P C +GHC NTPG + C+C GFT + G C
Sbjct: 2486 NDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGC 2526
Score = 243 bits (594), Expect = 2e-63
Identities = 157/448 (35%), Positives = 205/448 (45%), Gaps = 74/448 (16%)
Query: 157 TCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI-----------DE 205
TC DVNECE GVC +G C NT GSF C C G D ++CVD+ DE
Sbjct: 866 TCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDE 925
Query: 206 CADN-DALCRGGRCVNTAGSF---RCE-------------CGHGMELAP-DRLS----CK 243
C R C + G+ CE C G+ A D LS K
Sbjct: 926 CGVTLPGKYRMDFCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYK 985
Query: 244 DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHSCV 302
D++EC + G+C++G C N +G++ C C G+A + + C Q +CV
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 303 NTPGSYHCTCREGWHLR-ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
NTPGS+ C C G+ ++C D+DECA C GG C NT GSY C C G +
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
A G C+DIDEC S+ + LC G C N IG+F C C G
Sbjct: 1106 AKGT--ACEDIDEC----------SLSD----------GLCPHGQCVNVIGAFQCSCHAG 1143
Query: 422 YSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVD 477
+ P++ C D +EC + G CD H CIN GS++C C G+ DG C DVD
Sbjct: 1144 FQSTPDR-QGCVDINECRVQNGGCDVH----CINTEGSYRCSCGQGYSLMPDGRACADVD 1198
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC N C + C N G RCLC G+ +RT CVD+DEC +P +C
Sbjct: 1199 ECEENPRVC-DQGHCTNMPGGHRCLCYDGFMATP-DMRT------CVDVDECDLNPHICL 1250
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
+G C NT G + C C +G+ C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGC 1278
Score = 239 bits (586), Expect = 1e-62
Identities = 169/500 (33%), Positives = 218/500 (43%), Gaps = 87/500 (17%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC + P C HG C N+ G + C C+PG++ CVDV+EC + G+C G C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NTEGSF C C G++ K CVD +ECA + +C G C+N GSF C C G LA
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATS-TMCVNGVCLNEDGSFSCLCKPGFLLA 564
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTY--QC-----------VCDEGYAQST---- 279
P C DIDEC T GIC NG C N G++ QC VC + + +ST
Sbjct: 565 PGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 280 --------------VKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
KS CQ + C G + DGR
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 326 RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
DI+ECA C G C N GSY C C G A+G C D+DECA
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKD--CTDVDECA--------- 729
Query: 386 SVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
++ L LC G C N+ GS+ C CP G+ + C D DEC C
Sbjct: 730 -LNSL----------LCDNGWCQNSPGSYSCSCPPGFHFWQDT-EICKDVDECLSSPC-- 775
Query: 446 HPAADCINLPGSFQCRCRDGWRGD--GATCED---------VDE--CLTNNGGCHPRATC 492
+ C NL GS+ C+C G R D G C D + E C N G R+ C
Sbjct: 776 -VSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSEC 834
Query: 493 ANTDGSF------RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG 546
T G+ RC D G+ T +C D++EC + P +C NG C NT G
Sbjct: 835 CATLGAAWGSPCERCEIDPAC-ARGFARMTGV---TCDDVNECESFPGVCPNGRCVNTAG 890
Query: 547 GYECDCDVGFTRAADGRSCL 566
+ C+C G A GR C+
Sbjct: 891 SFRCECPEGLMLDASGRLCV 910
Score = 239 bits (584), Expect = 2e-62
Identities = 154/457 (33%), Positives = 206/457 (45%), Gaps = 63/457 (13%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG-D 175
+++EC+ P LC RC N G + C C GY C DV+EC C G +
Sbjct: 2166 DIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGME 2224
Query: 176 CHNTEGSFTCHCRPGYKADDFS-KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C N G+F C C PG + S + C D +EC LC GRCVNTAGSFRC+C G +
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 235 LAPDRLSCKDIDE----CSITSGICSNGACENQMGTY-QCVCDEGYAQSTVKSHXXXXXX 289
+P C DI + + +C + + ++ T +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGP---------- 2334
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
RC+ + +Y C G A+GR D+DEC A C G+C N++GS
Sbjct: 2335 ------RCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLCAHGECINSLGS 2385
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
+ C C G P A TC D+DEC+ Q+P+ C C N
Sbjct: 2386 FRCHCQAGYTPDATAT--TCLDMDECS--------------------QVPKPC-TFLCKN 2422
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
T GSF+C CP GY ++ E G C D DEC +C C+N G+F CRC G+
Sbjct: 2423 TKGSFLCSCPRGYLLE-EDGRTCKDLDECTSRQHNCQFL--CVNTVGAFTCRCPPGFTQH 2479
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
C D DEC G C C NT GSFRC C G+ V + C D++EC
Sbjct: 2480 HQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGF-------TLVSSGHGCEDVNEC 2532
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ P C++G C N GGY C C GFT+ + C+
Sbjct: 2533 -DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCV 2567
Score = 231 bits (564), Expect = 7e-60
Identities = 159/484 (32%), Positives = 212/484 (43%), Gaps = 73/484 (15%)
Query: 118 EVNECAAFPGLCGHGR---CRNLLGGFTCDCFPGYEK-DSKNHTCVDVNECEIVDGVCGD 173
+V+ECA C H R C+NL+G F C C PG C D NEC +C +
Sbjct: 2207 DVDECADGQQDC-HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVN 2265
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDE--CADN--DALCRGGRCVNTAGS-FRCE 228
G C NT GSF C C G++ C DI + C +CR + A + C
Sbjct: 2266 GRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECC 2325
Query: 229 CGHGM------ELAP------DRLSC----------KDIDECSITSGICSNGACENQMGT 266
CG G EL P R C +D+DEC + + +C++G C N +G+
Sbjct: 2326 CGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGS 2385
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR 326
++C C GY + C C NT GS+ C+C G+ L DGR+C+
Sbjct: 2386 FRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
D+DEC C C NTVG++TC C G C D DEC+
Sbjct: 2446 DLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFTQH----HQACFDNDECSAQ-------- 2492
Query: 387 VDELQKSVDPQIPELCGA-GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
P CGA G CHNT GSF C+C G+++ G C D +EC+ G C
Sbjct: 2493 ------------PGPCGAHGHCHNTPGSFRCECHQGFTLV-SSGHGCEDVNECD-GPHRC 2538
Query: 446 HPAADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N G ++C C G+ A C D +EC + C A+C NT G FRC+C
Sbjct: 2539 QHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGS-ASCRNTLGGFRCVC 2595
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGR 563
+G+ D + C D+DECA C C+NTPGG+ C C G+ RA G
Sbjct: 2596 PSGFDFDQ-------ALGGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQGH 2647
Query: 564 SCLG 567
G
Sbjct: 2648 CVSG 2651
Score = 230 bits (562), Expect = 1e-59
Identities = 151/465 (32%), Positives = 209/465 (44%), Gaps = 52/465 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C C GYE + C DV+EC + +C +G C
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQ 741
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N+ GS++C C PG+ ++IC D+DEC + C G C N AGS+ C+CG G L P
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDP 799
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
C D T G C E++ C+ ++++S C
Sbjct: 800 SGTFCLD-----STKGTCWLKIQESR-------CEVNLQGASLRSE-CCATLGAAWGSPC 846
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+ C P C G+ R G +C D++EC C G+C NT GS+ C C +G
Sbjct: 847 ER-CEIDP-----ACARGF-ARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEG 899
Query: 358 LVPSAAGAKPTCQDI-----------DECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
L+ A+G C D+ DEC + M D S+ C A
Sbjct: 900 LMLDASGR--LCVDVRLEPCFLRWDEDECGVTLPGKYRM--DFCCCSIGAVWGVECEACP 955
Query: 407 CHNTIGSFVCQCPDGYSVKPEQ----GPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
++ F CP G P D +EC++ C C N GSF C C
Sbjct: 956 DPESL-EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCAC 1013
Query: 463 RDGWRGDG--ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ D C D+DEC + C + TC NT GSF C C GY+ G+ L +
Sbjct: 1014 AGGFALDAQERNCTDIDECRISPDLC-GQGTCVNTPGSFECECFPGYE-SGFML-----M 1066
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+C+D+DECA DP LC G C+NT G Y+C C G A G +C
Sbjct: 1067 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 230 bits (562), Expect = 1e-59
Identities = 165/510 (32%), Positives = 215/510 (42%), Gaps = 94/510 (18%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C--EIVDGVCG 172
++++EC+ P LC G C N G F C C PG+ H C D + C G C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCS 2027
Query: 173 DGDCHN-TEGSFTCHCRPGYKADD------------FSKIC--------------VDIDE 205
N T+ C RPG D F ++C D++E
Sbjct: 2028 VPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNE 2087
Query: 206 CADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMG 265
CA+N +C G CVNT GSFRCEC G L ++C D DECS+ C G C N +G
Sbjct: 2088 CAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-GHPCGQGTCTNVIG 2146
Query: 266 TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
++C C +G+ + + C C NT GSY CTC G+ LR DG C
Sbjct: 2147 GFECACADGFEPGLMMT-CEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMC 2205
Query: 326 RDIDECAGGARPC--GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
RD+DECA G + C G +C+N +G++ C C G+ P G+ C D +EC
Sbjct: 2206 RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRP-LPGSGEGCTDDNEC-------- 2256
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKP--------EQGPA---- 431
Q P+LC G C NT GSF C C +G+ P QGP
Sbjct: 2257 -----HAQ-------PDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Query: 432 ----C----TDDDECELGTCDC------HPAADCINLPGSFQCR--CRDGWRGDGATCED 475
C + + C C P + LPG+ R C G G A D
Sbjct: 2305 LQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG-SGYTAEGRD 2363
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
VDEC C C N+ GSFRC C GY D +C+D+DEC+ P
Sbjct: 2364 VDECRMLAHLC-AHGECINSLGSFRCHCQAGYTPD-------ATATTCLDMDECSQVPKP 2415
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C NT G + C C G+ DGR+C
Sbjct: 2416 C-TFLCKNTKGSFLCSCPRGYLLEEDGRTC 2444
Score = 195 bits (475), Expect = 4e-49
Identities = 135/431 (31%), Positives = 183/431 (42%), Gaps = 60/431 (13%)
Query: 147 PGYEKDSKNHTCV---DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
PG E N V D++EC+ + G+C GDC NT GSF C C PGY + ++IC DI
Sbjct: 1547 PGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDI 1606
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC+ + ++C G C NT G++ C C +C D+ + NG C+N+
Sbjct: 1607 DECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNE 1664
Query: 264 MG----TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
+ C C Q+ + Q C N + G L
Sbjct: 1665 LAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDY---QILCGNQAPGFLTDIHTGKPL- 1720
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
DIDEC C G C N +GS+ C C G + C+D+DEC
Sbjct: 1721 -------DIDECGEIPAICANGICINQIGSFRCECPAGF--NYNSILLACEDVDECGSRE 1771
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC- 438
S Q++ D C N GS+ C+C GY + P G AC +EC
Sbjct: 1772 SPC--------QQNAD-----------CINIPGSYRCKCTRGYKLSP--GGACVGRNECR 1810
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTD 496
E+ H DC++ GS+ C C G++ D C D+DEC G TC N
Sbjct: 1811 EIPNVCSH--GDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG---NGTCKNII 1865
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN-DPTLCENGHCSNTPGGYECDCDVG 555
GS+ CLC G+ G CVD DEC +C GHC NT G + C C G
Sbjct: 1866 GSYNCLCFPGFVVTHNG--------DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDG 1917
Query: 556 FTRAADGRSCL 566
F ADG++C+
Sbjct: 1918 FELTADGKNCV 1928
Score = 168 bits (408), Expect = 5e-41
Identities = 88/250 (35%), Positives = 118/250 (47%), Gaps = 9/250 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC+ P C C+N G F C C GY + TC D++EC C C
Sbjct: 2404 LDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC-QFLC 2461
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G+FTC C PG+ + C D DEC+ C G C NT GSFRCEC G L
Sbjct: 2462 VNTVGAFTCRCPPGFT--QHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTL 2519
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
C+D++EC C +G C+NQ+G Y+C C +G+ Q + +
Sbjct: 2520 VSSGHGCEDVNECDGPHR-CQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPP 2577
Query: 296 RC-QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C SC NT G + C C G+ C+D+DECAG PC C NT G + C C
Sbjct: 2578 TCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPC-SYSCANTPGGFLCGC 2636
Query: 355 TDGLVPSAAG 364
G + G
Sbjct: 2637 PQGYFRAGQG 2646
Score = 136 bits (329), Expect = 2e-31
Identities = 122/399 (30%), Positives = 155/399 (38%), Gaps = 60/399 (15%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD--VNEC--EIVDGVC-G 172
+V+EC A PGLC G C N++G F C C G+ + C D C + G C G
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAG 306
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDE------CADNDALCRGGRCVNTAGSFR 226
D H T C + A ++C CA L G +
Sbjct: 307 DLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGF 366
Query: 227 CECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
G G L P RL+ D GI S G + +GT A
Sbjct: 367 GSNGMGPPLGPARLNPHGSD----ARGIPSLGPGNSNIGT---------ATLNQTIDICR 413
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT 346
RC + TP SY C C G+ G C D+DEC + PC G C N
Sbjct: 414 HFTNLCLNGRC----LPTPSSYRCECNVGYTQDVRG-ECIDVDECT--SSPCHHGDCVNI 466
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
G+Y C C G A + C D+DEC ++S LC G
Sbjct: 467 PGTYHCRCYPGF--QATPTRQACVDVDEC--IVS------------------GGLCHLGR 504
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C NT GSF C C G+ + P+ G C D +EC T + C+N GSF C C+ G+
Sbjct: 505 CVNTEGSFQCVCNAGFELSPD-GKNCVDHNECATSTMCVNGV--CLNEDGSFSCLCKPGF 561
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
G C D+DEC T G C NT+GSFRC C
Sbjct: 562 LLAPGGHYCMDIDECQT--PGICVNGHCTNTEGSFRCQC 598
Score = 134 bits (324), Expect = 8e-31
Identities = 86/241 (35%), Positives = 105/241 (43%), Gaps = 39/241 (16%)
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
ID C C G+C T SY C C G G C D+DEC
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE---CIDVDECTS---------- 455
Query: 388 DELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
P C G C N G++ C+C G+ P + AC D DEC + CH
Sbjct: 456 -------SP-----CHHGDCVNIPGTYHCRCYPGFQATPTR-QACVDVDECIVSGGLCH- 501
Query: 448 AADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
C+N GSFQC C G+ DG C D +EC T+ C C N DGSF CLC
Sbjct: 502 LGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM-C-VNGVCLNEDGSFSCLCKP 559
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G+ G + C+DIDEC P +C NGHC+NT G + C C G DGR C
Sbjct: 560 GFLLAPGG-------HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC 611
Query: 566 L 566
+
Sbjct: 612 V 612
Score = 82.6 bits (195), Expect = 3e-15
Identities = 117/458 (25%), Positives = 154/458 (33%), Gaps = 54/458 (11%)
Query: 136 NLLGG-FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKAD 194
N+ G F C PG+ CV I CG+G C C C G A
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV----VPICRRACGEGFCSQPN---LCTCADGTLAP 110
Query: 195 D--FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM--ELAPDRLSCKDIDECSI 250
S+ C N CRG C+ G CG + + C + C+
Sbjct: 111 SCGVSRGSGCSVSCM-NGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCAC 169
Query: 251 TSGICSNGACENQMGTYQC---VCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
G CE T C V EG C P
Sbjct: 170 VYGFMGP-QCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQ 228
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSAAGA 365
H CR G+ +C+D+DEC C GG C N VGS+ C C G L S+A
Sbjct: 229 PH-PCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 366 KP----TCQDI---DECA-DLIS--TIIMMSVDELQKSVDPQIPELC---GAGSCHNTIG 412
+ C + CA DL T D + +PELC G+
Sbjct: 288 EDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCA 347
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP-AADCINLPGSFQCRCRDGWRGDGA 471
+ P + P ++ LG +P +D +P G
Sbjct: 348 QRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQ 407
Query: 472 TCEDVDECLTN---NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
T D+ TN NG C P T S+RC C+ GY D G C+D+DE
Sbjct: 408 TI-DICRHFTNLCLNGRCLP------TPSSYRCECNVGYTQDVRG--------ECIDVDE 452
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C + P C +G C N PG Y C C GF ++C+
Sbjct: 453 CTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACV 488
Score = 47.6 bits (108), Expect = 1e-04
Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Query: 4 GRCSGPLPTDVLRAVCCCSAL-GKAWGNQRCEPCPKKGTDAYQNLC 48
G+CS P + + CCCS G+ WG+ CE CP++G+ A+Q LC
Sbjct: 2024 GKCSVPKAFNTTKTRCCCSKRPGEGWGDP-CELCPQEGSAAFQELC 2068
Score = 46.0 bits (104), Expect = 4e-04
Identities = 20/35 (57%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V RA CCC G+ WG RCE CP GT AY+ LC
Sbjct: 2319 VTRAECCCGG-GRGWG-PRCELCPLPGTSAYRKLC 2351
Score = 34.3 bits (75), Expect = 1.2
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C LP CCCS +G WG + CE CP + + +LC
Sbjct: 926 CGVTLPGKYRMDFCCCS-IGAVWGVE-CEACPDPESLEFASLC 966
>AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 436 bits (1075), Expect = e-122
Identities = 196/449 (43%), Positives = 252/449 (56%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC FPGLC HG CRN +G F C C G+ D++ C D++EC I +CG G C
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY++ K C+D+DECA + LCRGG C NT GS++C+C G EL
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+C+DIDECS++ G+C +G C N +G +QC C G+ + +
Sbjct: 1106 AKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGG 1165
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C C+NT GSY C+C +G+ L DGR+C D+DEC R C G C N G + C C D
Sbjct: 1166 CDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYD 1225
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A TC D+DEC DL P +C G C NT GSFVC
Sbjct: 1226 GFM--ATPDMRTCVDVDEC-DL-------------------NPHICLHGDCENTKGSFVC 1263
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GY V+ + C+D DECE+G +C A C+N+PGSF CRC GW GDG C D+
Sbjct: 1264 HCQLGYMVR-KGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDL 1322
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC++ C PR C N GS+RC C G+ GDG + C D DECA + LC
Sbjct: 1323 DECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDG---------FFCEDRDECAENVDLC 1373
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+NG C N PGGY C+C++GF D R+C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRAC 1402
Score = 299 bits (734), Expect = 2e-80
Identities = 162/454 (35%), Positives = 214/454 (47%), Gaps = 42/454 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+V+ECA P LC G C N G + C C PG+E +K C D++EC + DG+C G C
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQC 1129
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G+F C C G+++ + CVDI+EC + C C+NT GS+RC CG G L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC-DVHCINTEGSYRCSCGQGYSLM 1188
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
PD +C D+DEC +C G C N G ++C+C +G+ +
Sbjct: 1189 PDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHI 1248
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTC 354
C H C NT GS+ C C+ G+ +R C D+DEC G C C N GS++C C
Sbjct: 1249 CLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRC 1308
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G V G C D+DEC + P+ G C N GS+
Sbjct: 1309 LPGWV----GDGFECHDLDECV------------SQEHRCSPR-------GDCLNVPGSY 1345
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C C G++ G C D DEC D C+N PG ++C C G+ D
Sbjct: 1346 RCTCRQGFA---GDGFFCEDRDEC-AENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRA 1401
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C+DVDEC G +C N G FRC+C+ GY+ D G +C DI+ECA D
Sbjct: 1402 CQDVDECA--QGNLCAFGSCENLPGMFRCICNGGYELDRGG-------GNCTDINECA-D 1451
Query: 533 PTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P C NG C NTPG Y C C F G C+
Sbjct: 1452 PVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Score = 259 bits (634), Expect = 2e-68
Identities = 181/571 (31%), Positives = 248/571 (43%), Gaps = 70/571 (12%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
+G CS + V RA CCCS LG+AWGN CE CP T Y+ LC G PN+
Sbjct: 1502 SGISCSAEIGVGVTRASCCCS-LGRAWGNP-CELCPMANTTEYRTLCPG-GEGFQPNR-- 1556
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNE 121
+T I + DE + G G + +++E
Sbjct: 1557 ------ITVILEDI--DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDE 1608
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C-EIVDGVCGDGDCHN 178
C+ +CG G C N LG +TC C Y + + + C+D+ + C +G C + N
Sbjct: 1609 CSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFN 1668
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
C C +++ C + C + C N A F + G L
Sbjct: 1669 VTRKMCC-CSYNI-GQAWNRPC---EACPTPISPDYQILCGNQAPGFLTDIHTGKPL--- 1720
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
DIDEC IC+NG C NQ+G+++C C G+ +++ CQ
Sbjct: 1721 -----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 299 HS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
+ C+N PGSY C C G+ L + G +C +EC C G C +T GSY C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKL-SPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHR 1834
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G SA + C DIDEC D Q P CG G+C N IGS+ C
Sbjct: 1835 GFQASAD--QTLCMDIDEC-------------------DRQ-P--CGNGTCKNIIGSYNC 1870
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCE 474
C G+ V C D DEC C+N GSF C C+DG+ DG C
Sbjct: 1871 LCFPGFVVT--HNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCV 1928
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D +ECL+ G C P TC N +GSFRC+C G++ C+DIDEC+ +P
Sbjct: 1929 DTNECLSLAGTCLP-GTCQNLEGSFRCICPPGFQVQSD---------HCIDIDECSEEPN 1978
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
LC G C+N+PG ++C C GF + +G C
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 258 bits (633), Expect = 3e-68
Identities = 163/475 (34%), Positives = 220/475 (46%), Gaps = 73/475 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGD 175
++++EC P +C +G C N +G F C+C G+ +S C DV+EC + C + D
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C GYK CV +EC + +C G C++T GS+ C C G +
Sbjct: 1780 CINIPGSYRCKCTRGYKLSP-GGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D+ C DIDEC C NG C+N +G+Y C+C G+ +
Sbjct: 1839 SADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+ C+NT GS+HC C++G+ L ADG++C D +EC A C G C+N GS+ C C
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCIC 1956
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + C DIDEC+ + P LC G+C N+ GSF
Sbjct: 1957 PPGFQVQS----DHCIDIDECS--------------------EEPNLCLFGTCTNSPGSF 1992
Query: 415 VCQCPDGYSVKPEQGPACTDDDE--C----ELGTCDCHPAAD-------CINLPG----- 456
C CP G+ V + G C D + C E G C A + C PG
Sbjct: 1993 QCLCPPGF-VLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGD 2051
Query: 457 -----------SFQCRCRDGW---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+FQ C G G + EDV+EC N G C C NTDGSFRC
Sbjct: 2052 PCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVC-TNGVCVNTDGSFRCE 2110
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECA-NDPTLCENGHCSNTPGGYECDCDVGF 556
C GY D G+ +CVD DEC+ P C G C+N GG+EC C GF
Sbjct: 2111 CPFGYSLDFTGI-------NCVDTDECSVGHP--CGQGTCTNVIGGFECACADGF 2156
Score = 258 bits (631), Expect = 5e-68
Identities = 169/524 (32%), Positives = 227/524 (43%), Gaps = 36/524 (6%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRC-EPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
GGRC+G L R CCC G+ W E CP +G++ +Q LC LLP +
Sbjct: 301 GGRCAGDLAGHYTRRQCCCDR-GRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGL 359
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGE-NXXXXXXXXXXXXXXXXXXXXXXXXQMEVN 120
P +G NG G N ++
Sbjct: 360 FP---------GLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTID 410
Query: 121 ECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTE 180
C F LC +GRC + C+C GY +D + C+DV+EC C GDC N
Sbjct: 411 ICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDEC--TSSPCHHGDCVNIP 467
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
G++ C C PG++A + CVD+DEC + LC GRCVNT GSF+C C G EL+PD
Sbjct: 468 GTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+C D +EC+ TS +C NG C N+ G++ C+C G+ + +
Sbjct: 528 NCVDHNECA-TSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH 586
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCR----NTVGSYTCTCTD 356
C NT GS+ C C G + DGR C D + G C TV C C +
Sbjct: 587 CTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCAN 646
Query: 357 GLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
P +P CQ + E L S+ + ++ D + PE+C G C N
Sbjct: 647 ---PDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR 702
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GD 469
GS+ C C GY G CTD DEC L + C C N PGS+ C C G+ D
Sbjct: 703 GSYRCVCNLGYEA-GASGKDCTDVDECALNSLLCDNGW-CQNSPGSYSCSCPPGFHFWQD 760
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
C+DVDECL++ C C N GS+ C C G + D G
Sbjct: 761 TEICKDVDECLSS--PC-VSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 251 bits (614), Expect = 6e-66
Identities = 155/466 (33%), Positives = 208/466 (44%), Gaps = 32/466 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC P +C G C N+ GG C C+ G+ TCVDV+EC++ +C GDC
Sbjct: 1196 DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCE 1255
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC+ GY + C D+DEC C C+N GSF C C G
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--V 1313
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D C D+DEC CS G C N G+Y+C C +G+A
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL- 1372
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C + C+N PG Y C C G+ D R+C+D+DECA G C G C N G + C C
Sbjct: 1373 -CDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQG-NLCAFGSCENLPGMFRCIC 1430
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTI--IMMSVDELQKSVDPQIPEL--CGAGSCHNT 410
G G C DI+ECAD ++ I + ++ PQ EL G G
Sbjct: 1431 NGGYELDRGGG--NCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTR 1488
Query: 411 IGSFVCQCPD----GYSVKPEQGPACTDDD-ECELGTCDCHPAADC-INLPGSFQCRC-- 462
G+ + D G S E G T C LG +P C + ++ C
Sbjct: 1489 AGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPG 1548
Query: 463 RDGWRGDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
+G++ + T ED+DEC G C C NT GSF+C C GY +
Sbjct: 1549 GEGFQPNRITVILEDIDECQELPGLCQ-GGDCVNTFGSFQCECPPGYHLSEH-------T 1600
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DIDEC+ ++C G C NT G Y C C + + G +C+
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCM 1646
Score = 247 bits (604), Expect = 9e-65
Identities = 156/461 (33%), Positives = 199/461 (43%), Gaps = 31/461 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNECA PG+C +G C N G F C+C GY D CVD +EC V CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCT 2142
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G F C C G++ C DIDEC+ N LC RC NT GS+ C C G L
Sbjct: 2143 NVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLC-AFRCHNTEGSYLCTCPAGYTLRE 2200
Query: 238 DRLSCKDIDECSITSGIC-SNG-ACENQMGTYQCVCDEGYAQSTVKSHX-XXXXXXXXXX 294
D C+D+DEC+ C + G C+N +GT+ CVC G
Sbjct: 2201 DGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQP 2260
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN-TVGSYTC 352
C + CVNT GS+ C C EG+ C DI + A CR+ + S
Sbjct: 2261 DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVL-QTMCRSLSSSSEAV 2319
Query: 353 TCTDGLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
T + G P C+ L + + + LC G C
Sbjct: 2320 TRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGEC 2379
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW- 466
N++GSF C C GY+ C D DEC C C N GSF C C G+
Sbjct: 2380 INSLGSFRCHCQAGYT-PDATATTCLDMDECSQVPKPC--TFLCKNTKGSFLCSCPRGYL 2436
Query: 467 -RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
DG TC+D+DEC + C + C NT G+F C C G+ +C D
Sbjct: 2437 LEEDGRTCKDLDECTSRQHNC--QFLCVNTVGAFTCRCPPGFTQHH---------QACFD 2485
Query: 526 IDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DEC+ P C +GHC NTPG + C+C GFT + G C
Sbjct: 2486 NDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGC 2526
Score = 242 bits (593), Expect = 2e-63
Identities = 157/448 (35%), Positives = 203/448 (45%), Gaps = 74/448 (16%)
Query: 157 TCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI-----------DE 205
TC DVNECE GVC +G C NT GSF C C G D ++CVD+ DE
Sbjct: 866 TCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDE 925
Query: 206 CADN-------DALCR------GGRCVNTAG----SFRCECGHGMELAP-DRLS----CK 243
C D C G C F C G+ A D LS K
Sbjct: 926 CGVTLPGKYLMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYK 985
Query: 244 DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHSCV 302
D++EC + G+C++G C N +G++ C C G+A + + C Q +CV
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 303 NTPGSYHCTCREGWHLR-ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
NTPGS+ C C G+ ++C D+DECA C GG C NT GSY C C G +
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
A G C+DIDEC S+ + LC G C N IG+F C C G
Sbjct: 1106 AKGT--ACEDIDEC----------SLSD----------GLCPHGQCVNVIGAFQCSCHAG 1143
Query: 422 YSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVD 477
+ P++ C D +EC + G CD H CIN GS++C C G+ DG C DVD
Sbjct: 1144 FQSTPDR-QGCVDINECRVQNGGCDVH----CINTEGSYRCSCGQGYSLMPDGRACADVD 1198
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC N C + C N G RCLC G+ +RT CVD+DEC +P +C
Sbjct: 1199 ECEENPRVC-DQGHCTNMPGGHRCLCYDGFMATP-DMRT------CVDVDECDLNPHICL 1250
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
+G C NT G + C C +G+ C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGC 1278
Score = 239 bits (586), Expect = 1e-62
Identities = 169/500 (33%), Positives = 218/500 (43%), Gaps = 87/500 (17%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC + P C HG C N+ G + C C+PG++ CVDV+EC + G+C G C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NTEGSF C C G++ K CVD +ECA + +C G C+N GSF C C G LA
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATS-TMCVNGVCLNEDGSFSCLCKPGFLLA 564
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTY--QC-----------VCDEGYAQST---- 279
P C DIDEC T GIC NG C N G++ QC VC + + +ST
Sbjct: 565 PGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 280 --------------VKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
KS CQ + C G + DGR
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 326 RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
DI+ECA C G C N GSY C C G A+G C D+DECA
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKD--CTDVDECA--------- 729
Query: 386 SVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
++ L LC G C N+ GS+ C CP G+ + C D DEC C
Sbjct: 730 -LNSL----------LCDNGWCQNSPGSYSCSCPPGFHFWQDT-EICKDVDECLSSPC-- 775
Query: 446 HPAADCINLPGSFQCRCRDGWRGD--GATCED---------VDE--CLTNNGGCHPRATC 492
+ C NL GS+ C+C G R D G C D + E C N G R+ C
Sbjct: 776 -VSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSEC 834
Query: 493 ANTDGSF------RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG 546
T G+ RC D G+ T +C D++EC + P +C NG C NT G
Sbjct: 835 CATLGAAWGSPCERCEIDPAC-ARGFARMTGV---TCDDVNECESFPGVCPNGRCVNTAG 890
Query: 547 GYECDCDVGFTRAADGRSCL 566
+ C+C G A GR C+
Sbjct: 891 SFRCECPEGLMLDASGRLCV 910
Score = 239 bits (584), Expect = 2e-62
Identities = 154/457 (33%), Positives = 206/457 (45%), Gaps = 63/457 (13%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG-D 175
+++EC+ P LC RC N G + C C GY C DV+EC C G +
Sbjct: 2166 DIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGME 2224
Query: 176 CHNTEGSFTCHCRPGYKADDFS-KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C N G+F C C PG + S + C D +EC LC GRCVNTAGSFRC+C G +
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 235 LAPDRLSCKDIDE----CSITSGICSNGACENQMGTY-QCVCDEGYAQSTVKSHXXXXXX 289
+P C DI + + +C + + ++ T +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGP---------- 2334
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
RC+ + +Y C G A+GR D+DEC A C G+C N++GS
Sbjct: 2335 ------RCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLCAHGECINSLGS 2385
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
+ C C G P A TC D+DEC+ Q+P+ C C N
Sbjct: 2386 FRCHCQAGYTPDATAT--TCLDMDECS--------------------QVPKPC-TFLCKN 2422
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
T GSF+C CP GY ++ E G C D DEC +C C+N G+F CRC G+
Sbjct: 2423 TKGSFLCSCPRGYLLE-EDGRTCKDLDECTSRQHNCQFL--CVNTVGAFTCRCPPGFTQH 2479
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
C D DEC G C C NT GSFRC C G+ V + C D++EC
Sbjct: 2480 HQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGF-------TLVSSGHGCEDVNEC 2532
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ P C++G C N GGY C C GFT+ + C+
Sbjct: 2533 -DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCV 2567
Score = 231 bits (566), Expect = 4e-60
Identities = 151/465 (32%), Positives = 210/465 (45%), Gaps = 52/465 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C C GYE + C DV+EC + +C +G C
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQ 741
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N+ GS++C C PG+ ++IC D+DEC + C G C N AGS+ C+CG G L P
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDP 799
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
C D T G C E++ C+ ++++S C
Sbjct: 800 SGTFCLD-----STKGTCWLKIQESR-------CEVNLQGASLRSE-CCATLGAAWGSPC 846
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+ C P C G+ R G +C D++EC C G+C NT GS+ C C +G
Sbjct: 847 ER-CEIDP-----ACARGF-ARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEG 899
Query: 358 LVPSAAGAKPTCQDI-----------DECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
L+ A+G C D+ DEC + +M D S+ C A
Sbjct: 900 LMLDASGR--LCVDVRLEPCFLRWDEDECGVTLPGKYLM--DVCCCSIGAVWGVECEACP 955
Query: 407 CHNTIGSFVCQCPDGYSVKPEQ----GPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
++ F CP G P D +EC++ C C N GSF C C
Sbjct: 956 DPESL-EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCAC 1013
Query: 463 RDGWRGDG--ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ D C D+DEC + C + TC NT GSF C C GY+ G+ L +
Sbjct: 1014 AGGFALDAQERNCTDIDECRISPDLC-GQGTCVNTPGSFECECFPGYE-SGFML-----M 1066
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+C+D+DECA DP LC G C+NT G Y+C C G A G +C
Sbjct: 1067 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 231 bits (564), Expect = 7e-60
Identities = 159/484 (32%), Positives = 212/484 (43%), Gaps = 73/484 (15%)
Query: 118 EVNECAAFPGLCGHGR---CRNLLGGFTCDCFPGYEK-DSKNHTCVDVNECEIVDGVCGD 173
+V+ECA C H R C+NL+G F C C PG C D NEC +C +
Sbjct: 2207 DVDECADGQQDC-HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVN 2265
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDE--CADN--DALCRGGRCVNTAGS-FRCE 228
G C NT GSF C C G++ C DI + C +CR + A + C
Sbjct: 2266 GRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECC 2325
Query: 229 CGHGM------ELAP------DRLSC----------KDIDECSITSGICSNGACENQMGT 266
CG G EL P R C +D+DEC + + +C++G C N +G+
Sbjct: 2326 CGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGS 2385
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR 326
++C C GY + C C NT GS+ C+C G+ L DGR+C+
Sbjct: 2386 FRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
D+DEC C C NTVG++TC C G C D DEC+
Sbjct: 2446 DLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFTQH----HQACFDNDECSAQ-------- 2492
Query: 387 VDELQKSVDPQIPELCGA-GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
P CGA G CHNT GSF C+C G+++ G C D +EC+ G C
Sbjct: 2493 ------------PGPCGAHGHCHNTPGSFRCECHQGFTLV-SSGHGCEDVNECD-GPHRC 2538
Query: 446 HPAADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N G ++C C G+ A C D +EC + C A+C NT G FRC+C
Sbjct: 2539 QHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGS-ASCRNTLGGFRCVC 2595
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGR 563
+G+ D + C D+DECA C C+NTPGG+ C C G+ RA G
Sbjct: 2596 PSGFDFDQ-------ALGGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQGH 2647
Query: 564 SCLG 567
G
Sbjct: 2648 CVSG 2651
Score = 230 bits (562), Expect = 1e-59
Identities = 165/510 (32%), Positives = 215/510 (42%), Gaps = 94/510 (18%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C--EIVDGVCG 172
++++EC+ P LC G C N G F C C PG+ H C D + C G C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCS 2027
Query: 173 DGDCHN-TEGSFTCHCRPGYKADD------------FSKIC--------------VDIDE 205
N T+ C RPG D F ++C D++E
Sbjct: 2028 VPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNE 2087
Query: 206 CADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMG 265
CA+N +C G CVNT GSFRCEC G L ++C D DECS+ C G C N +G
Sbjct: 2088 CAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-GHPCGQGTCTNVIG 2146
Query: 266 TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
++C C +G+ + + C C NT GSY CTC G+ LR DG C
Sbjct: 2147 GFECACADGFEPGLMMT-CEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMC 2205
Query: 326 RDIDECAGGARPC--GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
RD+DECA G + C G +C+N +G++ C C G+ P G+ C D +EC
Sbjct: 2206 RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRP-LPGSGEGCTDDNEC-------- 2256
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKP--------EQGPA---- 431
Q P+LC G C NT GSF C C +G+ P QGP
Sbjct: 2257 -----HAQ-------PDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Query: 432 ----C----TDDDECELGTCDC------HPAADCINLPGSFQCR--CRDGWRGDGATCED 475
C + + C C P + LPG+ R C G G A D
Sbjct: 2305 LQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG-SGYTAEGRD 2363
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
VDEC C C N+ GSFRC C GY D +C+D+DEC+ P
Sbjct: 2364 VDECRMLAHLC-AHGECINSLGSFRCHCQAGYTPD-------ATATTCLDMDECSQVPKP 2415
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C NT G + C C G+ DGR+C
Sbjct: 2416 C-TFLCKNTKGSFLCSCPRGYLLEEDGRTC 2444
Score = 195 bits (475), Expect = 4e-49
Identities = 135/431 (31%), Positives = 183/431 (42%), Gaps = 60/431 (13%)
Query: 147 PGYEKDSKNHTCV---DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
PG E N V D++EC+ + G+C GDC NT GSF C C PGY + ++IC DI
Sbjct: 1547 PGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDI 1606
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC+ + ++C G C NT G++ C C +C D+ + NG C+N+
Sbjct: 1607 DECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNE 1664
Query: 264 MG----TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
+ C C Q+ + Q C N + G L
Sbjct: 1665 LAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDY---QILCGNQAPGFLTDIHTGKPL- 1720
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
DIDEC C G C N +GS+ C C G + C+D+DEC
Sbjct: 1721 -------DIDECGEIPAICANGICINQIGSFRCECPAGF--NYNSILLACEDVDECGSRE 1771
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC- 438
S Q++ D C N GS+ C+C GY + P G AC +EC
Sbjct: 1772 SPC--------QQNAD-----------CINIPGSYRCKCTRGYKLSP--GGACVGRNECR 1810
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTD 496
E+ H DC++ GS+ C C G++ D C D+DEC G TC N
Sbjct: 1811 EIPNVCSH--GDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG---NGTCKNII 1865
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN-DPTLCENGHCSNTPGGYECDCDVG 555
GS+ CLC G+ G CVD DEC +C GHC NT G + C C G
Sbjct: 1866 GSYNCLCFPGFVVTHNG--------DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDG 1917
Query: 556 FTRAADGRSCL 566
F ADG++C+
Sbjct: 1918 FELTADGKNCV 1928
Score = 168 bits (408), Expect = 5e-41
Identities = 88/250 (35%), Positives = 118/250 (47%), Gaps = 9/250 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC+ P C C+N G F C C GY + TC D++EC C C
Sbjct: 2404 LDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC-QFLC 2461
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G+FTC C PG+ + C D DEC+ C G C NT GSFRCEC G L
Sbjct: 2462 VNTVGAFTCRCPPGFT--QHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTL 2519
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
C+D++EC C +G C+NQ+G Y+C C +G+ Q + +
Sbjct: 2520 VSSGHGCEDVNECDGPHR-CQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPP 2577
Query: 296 RC-QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C SC NT G + C C G+ C+D+DECAG PC C NT G + C C
Sbjct: 2578 TCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPC-SYSCANTPGGFLCGC 2636
Query: 355 TDGLVPSAAG 364
G + G
Sbjct: 2637 PQGYFRAGQG 2646
Score = 136 bits (329), Expect = 2e-31
Identities = 122/399 (30%), Positives = 155/399 (38%), Gaps = 60/399 (15%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD--VNEC--EIVDGVC-G 172
+V+EC A PGLC G C N++G F C C G+ + C D C + G C G
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAG 306
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDE------CADNDALCRGGRCVNTAGSFR 226
D H T C + A ++C CA L G +
Sbjct: 307 DLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGF 366
Query: 227 CECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
G G L P RL+ D GI S G + +GT A
Sbjct: 367 GSNGMGPPLGPARLNPHGSD----ARGIPSLGPGNSNIGT---------ATLNQTIDICR 413
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT 346
RC + TP SY C C G+ G C D+DEC + PC G C N
Sbjct: 414 HFTNLCLNGRC----LPTPSSYRCECNVGYTQDVRG-ECIDVDECT--SSPCHHGDCVNI 466
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
G+Y C C G A + C D+DEC ++S LC G
Sbjct: 467 PGTYHCRCYPGF--QATPTRQACVDVDEC--IVS------------------GGLCHLGR 504
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C NT GSF C C G+ + P+ G C D +EC T + C+N GSF C C+ G+
Sbjct: 505 CVNTEGSFQCVCNAGFELSPD-GKNCVDHNECATSTMCVNGV--CLNEDGSFSCLCKPGF 561
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
G C D+DEC T G C NT+GSFRC C
Sbjct: 562 LLAPGGHYCMDIDECQT--PGICVNGHCTNTEGSFRCQC 598
Score = 134 bits (324), Expect = 8e-31
Identities = 86/241 (35%), Positives = 105/241 (43%), Gaps = 39/241 (16%)
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
ID C C G+C T SY C C G G C D+DEC
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE---CIDVDECTS---------- 455
Query: 388 DELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
P C G C N G++ C+C G+ P + AC D DEC + CH
Sbjct: 456 -------SP-----CHHGDCVNIPGTYHCRCYPGFQATPTR-QACVDVDECIVSGGLCH- 501
Query: 448 AADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
C+N GSFQC C G+ DG C D +EC T+ C C N DGSF CLC
Sbjct: 502 LGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM-C-VNGVCLNEDGSFSCLCKP 559
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G+ G + C+DIDEC P +C NGHC+NT G + C C G DGR C
Sbjct: 560 GFLLAPGG-------HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC 611
Query: 566 L 566
+
Sbjct: 612 V 612
Score = 82.6 bits (195), Expect = 3e-15
Identities = 117/458 (25%), Positives = 154/458 (33%), Gaps = 54/458 (11%)
Query: 136 NLLGG-FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKAD 194
N+ G F C PG+ CV I CG+G C C C G A
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV----VPICRRACGEGFCSQPN---LCTCADGTLAP 110
Query: 195 D--FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM--ELAPDRLSCKDIDECSI 250
S+ C N CRG C+ G CG + + C + C+
Sbjct: 111 SCGVSRGSGCSVSCM-NGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCAC 169
Query: 251 TSGICSNGACENQMGTYQC---VCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
G CE T C V EG C P
Sbjct: 170 VYGFMGP-QCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQ 228
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSAAGA 365
H CR G+ +C+D+DEC C GG C N VGS+ C C G L S+A
Sbjct: 229 PH-PCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 366 KP----TCQDI---DECA-DLIS--TIIMMSVDELQKSVDPQIPELC---GAGSCHNTIG 412
+ C + CA DL T D + +PELC G+
Sbjct: 288 EDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCA 347
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP-AADCINLPGSFQCRCRDGWRGDGA 471
+ P + P ++ LG +P +D +P G
Sbjct: 348 QRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQ 407
Query: 472 TCEDVDECLTN---NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
T D+ TN NG C P T S+RC C+ GY D G C+D+DE
Sbjct: 408 TI-DICRHFTNLCLNGRCLP------TPSSYRCECNVGYTQDVRG--------ECIDVDE 452
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C + P C +G C N PG Y C C GF ++C+
Sbjct: 453 CTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACV 488
Score = 47.6 bits (108), Expect = 1e-04
Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Query: 4 GRCSGPLPTDVLRAVCCCSAL-GKAWGNQRCEPCPKKGTDAYQNLC 48
G+CS P + + CCCS G+ WG+ CE CP++G+ A+Q LC
Sbjct: 2024 GKCSVPKAFNTTKTRCCCSKRPGEGWGDP-CELCPQEGSAAFQELC 2068
Score = 46.0 bits (104), Expect = 4e-04
Identities = 20/35 (57%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V RA CCC G+ WG RCE CP GT AY+ LC
Sbjct: 2319 VTRAECCCGG-GRGWG-PRCELCPLPGTSAYRKLC 2351
Score = 38.7 bits (86), Expect = 0.054
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C LP L VCCCS +G WG + CE CP + + +LC
Sbjct: 926 CGVTLPGKYLMDVCCCS-IGAVWGVE-CEACPDPESLEFASLC 966
>AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 436 bits (1075), Expect = e-122
Identities = 196/449 (43%), Positives = 252/449 (56%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC FPGLC HG CRN +G F C C G+ D++ C D++EC I +CG G C
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY++ K C+D+DECA + LCRGG C NT GS++C+C G EL
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+C+DIDECS++ G+C +G C N +G +QC C G+ + +
Sbjct: 1106 AKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGG 1165
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C C+NT GSY C+C +G+ L DGR+C D+DEC R C G C N G + C C D
Sbjct: 1166 CDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYD 1225
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A TC D+DEC DL P +C G C NT GSFVC
Sbjct: 1226 GFM--ATPDMRTCVDVDEC-DL-------------------NPHICLHGDCENTKGSFVC 1263
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GY V+ + C+D DECE+G +C A C+N+PGSF CRC GW GDG C D+
Sbjct: 1264 HCQLGYMVR-KGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDL 1322
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC++ C PR C N GS+RC C G+ GDG + C D DECA + LC
Sbjct: 1323 DECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDG---------FFCEDRDECAENVDLC 1373
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+NG C N PGGY C+C++GF D R+C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRAC 1402
Score = 299 bits (734), Expect = 2e-80
Identities = 162/454 (35%), Positives = 214/454 (47%), Gaps = 42/454 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+V+ECA P LC G C N G + C C PG+E +K C D++EC + DG+C G C
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQC 1129
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G+F C C G+++ + CVDI+EC + C C+NT GS+RC CG G L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC-DVHCINTEGSYRCSCGQGYSLM 1188
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
PD +C D+DEC +C G C N G ++C+C +G+ +
Sbjct: 1189 PDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHI 1248
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTC 354
C H C NT GS+ C C+ G+ +R C D+DEC G C C N GS++C C
Sbjct: 1249 CLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRC 1308
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G V G C D+DEC + P+ G C N GS+
Sbjct: 1309 LPGWV----GDGFECHDLDECV------------SQEHRCSPR-------GDCLNVPGSY 1345
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C C G++ G C D DEC D C+N PG ++C C G+ D
Sbjct: 1346 RCTCRQGFA---GDGFFCEDRDEC-AENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRA 1401
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C+DVDEC G +C N G FRC+C+ GY+ D G +C DI+ECA D
Sbjct: 1402 CQDVDECA--QGNLCAFGSCENLPGMFRCICNGGYELDRGG-------GNCTDINECA-D 1451
Query: 533 PTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P C NG C NTPG Y C C F G C+
Sbjct: 1452 PVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Score = 259 bits (634), Expect = 2e-68
Identities = 181/571 (31%), Positives = 248/571 (43%), Gaps = 70/571 (12%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
+G CS + V RA CCCS LG+AWGN CE CP T Y+ LC G PN+
Sbjct: 1502 SGISCSAEIGVGVTRASCCCS-LGRAWGNP-CELCPMANTTEYRTLCPG-GEGFQPNR-- 1556
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNE 121
+T I + DE + G G + +++E
Sbjct: 1557 ------ITVILEDI--DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDE 1608
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C-EIVDGVCGDGDCHN 178
C+ +CG G C N LG +TC C Y + + + C+D+ + C +G C + N
Sbjct: 1609 CSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFN 1668
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
C C +++ C + C + C N A F + G L
Sbjct: 1669 VTRKMCC-CSYNI-GQAWNRPC---EACPTPISPDYQILCGNQAPGFLTDIHTGKPL--- 1720
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
DIDEC IC+NG C NQ+G+++C C G+ +++ CQ
Sbjct: 1721 -----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 299 HS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
+ C+N PGSY C C G+ L + G +C +EC C G C +T GSY C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKL-SPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHR 1834
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G SA + C DIDEC D Q P CG G+C N IGS+ C
Sbjct: 1835 GFQASAD--QTLCMDIDEC-------------------DRQ-P--CGNGTCKNIIGSYNC 1870
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCE 474
C G+ V C D DEC C+N GSF C C+DG+ DG C
Sbjct: 1871 LCFPGFVVT--HNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCV 1928
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D +ECL+ G C P TC N +GSFRC+C G++ C+DIDEC+ +P
Sbjct: 1929 DTNECLSLAGTCLP-GTCQNLEGSFRCICPPGFQVQSD---------HCIDIDECSEEPN 1978
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
LC G C+N+PG ++C C GF + +G C
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 258 bits (633), Expect = 3e-68
Identities = 163/475 (34%), Positives = 220/475 (46%), Gaps = 73/475 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGD 175
++++EC P +C +G C N +G F C+C G+ +S C DV+EC + C + D
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C GYK CV +EC + +C G C++T GS+ C C G +
Sbjct: 1780 CINIPGSYRCKCTRGYKLSP-GGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D+ C DIDEC C NG C+N +G+Y C+C G+ +
Sbjct: 1839 SADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+ C+NT GS+HC C++G+ L ADG++C D +EC A C G C+N GS+ C C
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCIC 1956
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + C DIDEC+ + P LC G+C N+ GSF
Sbjct: 1957 PPGFQVQS----DHCIDIDECS--------------------EEPNLCLFGTCTNSPGSF 1992
Query: 415 VCQCPDGYSVKPEQGPACTDDDE--C----ELGTCDCHPAAD-------CINLPG----- 456
C CP G+ V + G C D + C E G C A + C PG
Sbjct: 1993 QCLCPPGF-VLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGD 2051
Query: 457 -----------SFQCRCRDGW---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+FQ C G G + EDV+EC N G C C NTDGSFRC
Sbjct: 2052 PCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVC-TNGVCVNTDGSFRCE 2110
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECA-NDPTLCENGHCSNTPGGYECDCDVGF 556
C GY D G+ +CVD DEC+ P C G C+N GG+EC C GF
Sbjct: 2111 CPFGYSLDFTGI-------NCVDTDECSVGHP--CGQGTCTNVIGGFECACADGF 2156
Score = 258 bits (631), Expect = 5e-68
Identities = 169/524 (32%), Positives = 227/524 (43%), Gaps = 36/524 (6%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRC-EPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
GGRC+G L R CCC G+ W E CP +G++ +Q LC LLP +
Sbjct: 301 GGRCAGDLAGHYTRRQCCCDR-GRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGL 359
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGE-NXXXXXXXXXXXXXXXXXXXXXXXXQMEVN 120
P +G NG G N ++
Sbjct: 360 FP---------GLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTID 410
Query: 121 ECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTE 180
C F LC +GRC + C+C GY +D + C+DV+EC C GDC N
Sbjct: 411 ICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDEC--TSSPCHHGDCVNIP 467
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
G++ C C PG++A + CVD+DEC + LC GRCVNT GSF+C C G EL+PD
Sbjct: 468 GTYHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+C D +EC+ TS +C NG C N+ G++ C+C G+ + +
Sbjct: 528 NCVDHNECA-TSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH 586
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCR----NTVGSYTCTCTD 356
C NT GS+ C C G + DGR C D + G C TV C C +
Sbjct: 587 CTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCAN 646
Query: 357 GLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
P +P CQ + E L S+ + ++ D + PE+C G C N
Sbjct: 647 ---PDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR 702
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GD 469
GS+ C C GY G CTD DEC L + C C N PGS+ C C G+ D
Sbjct: 703 GSYRCVCNLGYEA-GASGKDCTDVDECALNSLLCDNGW-CQNSPGSYSCSCPPGFHFWQD 760
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
C+DVDECL++ C C N GS+ C C G + D G
Sbjct: 761 TEICKDVDECLSS--PC-VSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 251 bits (614), Expect = 6e-66
Identities = 155/466 (33%), Positives = 208/466 (44%), Gaps = 32/466 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC P +C G C N+ GG C C+ G+ TCVDV+EC++ +C GDC
Sbjct: 1196 DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCE 1255
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC+ GY + C D+DEC C C+N GSF C C G
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--V 1313
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D C D+DEC CS G C N G+Y+C C +G+A
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL- 1372
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C + C+N PG Y C C G+ D R+C+D+DECA G C G C N G + C C
Sbjct: 1373 -CDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQG-NLCAFGSCENLPGMFRCIC 1430
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTI--IMMSVDELQKSVDPQIPEL--CGAGSCHNT 410
G G C DI+ECAD ++ I + ++ PQ EL G G
Sbjct: 1431 NGGYELDRGGG--NCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTR 1488
Query: 411 IGSFVCQCPD----GYSVKPEQGPACTDDD-ECELGTCDCHPAADC-INLPGSFQCRC-- 462
G+ + D G S E G T C LG +P C + ++ C
Sbjct: 1489 AGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPG 1548
Query: 463 RDGWRGDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
+G++ + T ED+DEC G C C NT GSF+C C GY +
Sbjct: 1549 GEGFQPNRITVILEDIDECQELPGLCQ-GGDCVNTFGSFQCECPPGYHLSEH-------T 1600
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DIDEC+ ++C G C NT G Y C C + + G +C+
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCM 1646
Score = 247 bits (604), Expect = 9e-65
Identities = 156/461 (33%), Positives = 199/461 (43%), Gaps = 31/461 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNECA PG+C +G C N G F C+C GY D CVD +EC V CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCT 2142
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G F C C G++ C DIDEC+ N LC RC NT GS+ C C G L
Sbjct: 2143 NVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLC-AFRCHNTEGSYLCTCPAGYTLRE 2200
Query: 238 DRLSCKDIDECSITSGIC-SNG-ACENQMGTYQCVCDEGYAQSTVKSHX-XXXXXXXXXX 294
D C+D+DEC+ C + G C+N +GT+ CVC G
Sbjct: 2201 DGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQP 2260
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN-TVGSYTC 352
C + CVNT GS+ C C EG+ C DI + A CR+ + S
Sbjct: 2261 DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVL-QTMCRSLSSSSEAV 2319
Query: 353 TCTDGLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
T + G P C+ L + + + LC G C
Sbjct: 2320 TRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGEC 2379
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW- 466
N++GSF C C GY+ C D DEC C C N GSF C C G+
Sbjct: 2380 INSLGSFRCHCQAGYT-PDATATTCLDMDECSQVPKPC--TFLCKNTKGSFLCSCPRGYL 2436
Query: 467 -RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
DG TC+D+DEC + C + C NT G+F C C G+ +C D
Sbjct: 2437 LEEDGRTCKDLDECTSRQHNC--QFLCVNTVGAFTCRCPPGFTQHH---------QACFD 2485
Query: 526 IDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DEC+ P C +GHC NTPG + C+C GFT + G C
Sbjct: 2486 NDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGC 2526
Score = 243 bits (594), Expect = 2e-63
Identities = 157/448 (35%), Positives = 205/448 (45%), Gaps = 74/448 (16%)
Query: 157 TCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI-----------DE 205
TC DVNECE GVC +G C NT GSF C C G D ++CVD+ DE
Sbjct: 866 TCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDE 925
Query: 206 CADN-DALCRGGRCVNTAGSF---RCE-------------CGHGMELAP-DRLS----CK 243
C R C + G+ CE C G+ A D LS K
Sbjct: 926 CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYK 985
Query: 244 DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHSCV 302
D++EC + G+C++G C N +G++ C C G+A + + C Q +CV
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 303 NTPGSYHCTCREGWHLR-ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
NTPGS+ C C G+ ++C D+DECA C GG C NT GSY C C G +
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
A G C+DIDEC S+ + LC G C N IG+F C C G
Sbjct: 1106 AKGT--ACEDIDEC----------SLSD----------GLCPHGQCVNVIGAFQCSCHAG 1143
Query: 422 YSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVD 477
+ P++ C D +EC + G CD H CIN GS++C C G+ DG C DVD
Sbjct: 1144 FQSTPDR-QGCVDINECRVQNGGCDVH----CINTEGSYRCSCGQGYSLMPDGRACADVD 1198
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC N C + C N G RCLC G+ +RT CVD+DEC +P +C
Sbjct: 1199 ECEENPRVC-DQGHCTNMPGGHRCLCYDGFMATP-DMRT------CVDVDECDLNPHICL 1250
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
+G C NT G + C C +G+ C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGC 1278
Score = 240 bits (588), Expect = 8e-63
Identities = 169/500 (33%), Positives = 218/500 (43%), Gaps = 87/500 (17%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC + P C HG C N+ G + C C+PG++ CVDV+EC + G+C G C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NTEGSF C C G++ K CVD +ECA + +C G C+N GSF C C G LA
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATS-TMCVNGVCLNEDGSFSCLCKPGFLLA 564
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTY--QC-----------VCDEGYAQST---- 279
P C DIDEC T GIC NG C N G++ QC VC + + +ST
Sbjct: 565 PGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 280 --------------VKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
KS CQ + C G + DGR
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 326 RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
DI+ECA C G C N GSY C C G A+G C D+DECA
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKD--CTDVDECA--------- 729
Query: 386 SVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
++ L LC G C N+ GS+ C CP G+ + C D DEC C
Sbjct: 730 -LNSL----------LCDNGWCQNSPGSYSCSCPPGFHFWQDT-EICKDVDECLSSPC-- 775
Query: 446 HPAADCINLPGSFQCRCRDGWRGD--GATCED---------VDE--CLTNNGGCHPRATC 492
+ C NL GS+ C+C G R D G C D + E C N G R+ C
Sbjct: 776 -VSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSEC 834
Query: 493 ANTDGSF------RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG 546
T G+ RC D G+ T +C D++EC + P +C NG C NT G
Sbjct: 835 CATLGAAWGSPCERCEIDPAC-ARGFARMTGV---TCDDVNECESFPGVCPNGRCVNTAG 890
Query: 547 GYECDCDVGFTRAADGRSCL 566
+ C+C G A GR C+
Sbjct: 891 SFRCECPEGLMLDASGRLCV 910
Score = 239 bits (584), Expect = 2e-62
Identities = 154/457 (33%), Positives = 206/457 (45%), Gaps = 63/457 (13%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG-D 175
+++EC+ P LC RC N G + C C GY C DV+EC C G +
Sbjct: 2166 DIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGME 2224
Query: 176 CHNTEGSFTCHCRPGYKADDFS-KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C N G+F C C PG + S + C D +EC LC GRCVNTAGSFRC+C G +
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 235 LAPDRLSCKDIDE----CSITSGICSNGACENQMGTY-QCVCDEGYAQSTVKSHXXXXXX 289
+P C DI + + +C + + ++ T +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGP---------- 2334
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
RC+ + +Y C G A+GR D+DEC A C G+C N++GS
Sbjct: 2335 ------RCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLCAHGECINSLGS 2385
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
+ C C G P A TC D+DEC+ Q+P+ C C N
Sbjct: 2386 FRCHCQAGYTPDATAT--TCLDMDECS--------------------QVPKPC-TFLCKN 2422
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
T GSF+C CP GY ++ E G C D DEC +C C+N G+F CRC G+
Sbjct: 2423 TKGSFLCSCPRGYLLE-EDGRTCKDLDECTSRQHNCQFL--CVNTVGAFTCRCPPGFTQH 2479
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
C D DEC G C C NT GSFRC C G+ V + C D++EC
Sbjct: 2480 HQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGF-------TLVSSGHGCEDVNEC 2532
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ P C++G C N GGY C C GFT+ + C+
Sbjct: 2533 -DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCV 2567
Score = 231 bits (564), Expect = 7e-60
Identities = 159/484 (32%), Positives = 212/484 (43%), Gaps = 73/484 (15%)
Query: 118 EVNECAAFPGLCGHGR---CRNLLGGFTCDCFPGYEK-DSKNHTCVDVNECEIVDGVCGD 173
+V+ECA C H R C+NL+G F C C PG C D NEC +C +
Sbjct: 2207 DVDECADGQQDC-HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVN 2265
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDE--CADN--DALCRGGRCVNTAGS-FRCE 228
G C NT GSF C C G++ C DI + C +CR + A + C
Sbjct: 2266 GRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECC 2325
Query: 229 CGHGM------ELAP------DRLSC----------KDIDECSITSGICSNGACENQMGT 266
CG G EL P R C +D+DEC + + +C++G C N +G+
Sbjct: 2326 CGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGS 2385
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR 326
++C C GY + C C NT GS+ C+C G+ L DGR+C+
Sbjct: 2386 FRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
D+DEC C C NTVG++TC C G C D DEC+
Sbjct: 2446 DLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFTQH----HQACFDNDECSAQ-------- 2492
Query: 387 VDELQKSVDPQIPELCGA-GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
P CGA G CHNT GSF C+C G+++ G C D +EC+ G C
Sbjct: 2493 ------------PGPCGAHGHCHNTPGSFRCECHQGFTLV-SSGHGCEDVNECD-GPHRC 2538
Query: 446 HPAADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N G ++C C G+ A C D +EC + C A+C NT G FRC+C
Sbjct: 2539 QHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGS-ASCRNTLGGFRCVC 2595
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGR 563
+G+ D + C D+DECA C C+NTPGG+ C C G+ RA G
Sbjct: 2596 PSGFDFDQ-------ALGGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQGH 2647
Query: 564 SCLG 567
G
Sbjct: 2648 CVSG 2651
Score = 230 bits (563), Expect = 9e-60
Identities = 151/465 (32%), Positives = 209/465 (44%), Gaps = 52/465 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C C GYE + C DV+EC + +C +G C
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQ 741
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N+ GS++C C PG+ ++IC D+DEC + C G C N AGS+ C+CG G L P
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDP 799
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
C D T G C E++ C+ ++++S C
Sbjct: 800 SGTFCLD-----STKGTCWLKIQESR-------CEVNLQGASLRSE-CCATLGAAWGSPC 846
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+ C P C G+ R G +C D++EC C G+C NT GS+ C C +G
Sbjct: 847 ER-CEIDP-----ACARGF-ARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEG 899
Query: 358 LVPSAAGAKPTCQDI-----------DECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
L+ A+G C D+ DEC + M D S+ C A
Sbjct: 900 LMLDASGR--LCVDVRLEPCFLRWDEDECGVTLPGKYRM--DVCCCSIGAVWGVECEACP 955
Query: 407 CHNTIGSFVCQCPDGYSVKPEQ----GPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
++ F CP G P D +EC++ C C N GSF C C
Sbjct: 956 DPESL-EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCAC 1013
Query: 463 RDGWRGDG--ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ D C D+DEC + C + TC NT GSF C C GY+ G+ L +
Sbjct: 1014 AGGFALDAQERNCTDIDECRISPDLC-GQGTCVNTPGSFECECFPGYE-SGFML-----M 1066
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+C+D+DECA DP LC G C+NT G Y+C C G A G +C
Sbjct: 1067 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 230 bits (562), Expect = 1e-59
Identities = 165/510 (32%), Positives = 215/510 (42%), Gaps = 94/510 (18%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C--EIVDGVCG 172
++++EC+ P LC G C N G F C C PG+ H C D + C G C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCS 2027
Query: 173 DGDCHN-TEGSFTCHCRPGYKADD------------FSKIC--------------VDIDE 205
N T+ C RPG D F ++C D++E
Sbjct: 2028 VPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNE 2087
Query: 206 CADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMG 265
CA+N +C G CVNT GSFRCEC G L ++C D DECS+ C G C N +G
Sbjct: 2088 CAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-GHPCGQGTCTNVIG 2146
Query: 266 TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
++C C +G+ + + C C NT GSY CTC G+ LR DG C
Sbjct: 2147 GFECACADGFEPGLMMT-CEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMC 2205
Query: 326 RDIDECAGGARPC--GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
RD+DECA G + C G +C+N +G++ C C G+ P G+ C D +EC
Sbjct: 2206 RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRP-LPGSGEGCTDDNEC-------- 2256
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKP--------EQGPA---- 431
Q P+LC G C NT GSF C C +G+ P QGP
Sbjct: 2257 -----HAQ-------PDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Query: 432 ----C----TDDDECELGTCDC------HPAADCINLPGSFQCR--CRDGWRGDGATCED 475
C + + C C P + LPG+ R C G G A D
Sbjct: 2305 LQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG-SGYTAEGRD 2363
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
VDEC C C N+ GSFRC C GY D +C+D+DEC+ P
Sbjct: 2364 VDECRMLAHLC-AHGECINSLGSFRCHCQAGYTPD-------ATATTCLDMDECSQVPKP 2415
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C NT G + C C G+ DGR+C
Sbjct: 2416 C-TFLCKNTKGSFLCSCPRGYLLEEDGRTC 2444
Score = 195 bits (475), Expect = 4e-49
Identities = 135/431 (31%), Positives = 183/431 (42%), Gaps = 60/431 (13%)
Query: 147 PGYEKDSKNHTCV---DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
PG E N V D++EC+ + G+C GDC NT GSF C C PGY + ++IC DI
Sbjct: 1547 PGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDI 1606
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC+ + ++C G C NT G++ C C +C D+ + NG C+N+
Sbjct: 1607 DECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNE 1664
Query: 264 MG----TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
+ C C Q+ + Q C N + G L
Sbjct: 1665 LAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDY---QILCGNQAPGFLTDIHTGKPL- 1720
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
DIDEC C G C N +GS+ C C G + C+D+DEC
Sbjct: 1721 -------DIDECGEIPAICANGICINQIGSFRCECPAGF--NYNSILLACEDVDECGSRE 1771
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC- 438
S Q++ D C N GS+ C+C GY + P G AC +EC
Sbjct: 1772 SPC--------QQNAD-----------CINIPGSYRCKCTRGYKLSP--GGACVGRNECR 1810
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTD 496
E+ H DC++ GS+ C C G++ D C D+DEC G TC N
Sbjct: 1811 EIPNVCSH--GDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG---NGTCKNII 1865
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN-DPTLCENGHCSNTPGGYECDCDVG 555
GS+ CLC G+ G CVD DEC +C GHC NT G + C C G
Sbjct: 1866 GSYNCLCFPGFVVTHNG--------DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDG 1917
Query: 556 FTRAADGRSCL 566
F ADG++C+
Sbjct: 1918 FELTADGKNCV 1928
Score = 168 bits (408), Expect = 5e-41
Identities = 88/250 (35%), Positives = 118/250 (47%), Gaps = 9/250 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC+ P C C+N G F C C GY + TC D++EC C C
Sbjct: 2404 LDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC-QFLC 2461
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G+FTC C PG+ + C D DEC+ C G C NT GSFRCEC G L
Sbjct: 2462 VNTVGAFTCRCPPGFT--QHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTL 2519
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
C+D++EC C +G C+NQ+G Y+C C +G+ Q + +
Sbjct: 2520 VSSGHGCEDVNECDGPHR-CQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPP 2577
Query: 296 RC-QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C SC NT G + C C G+ C+D+DECAG PC C NT G + C C
Sbjct: 2578 TCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPC-SYSCANTPGGFLCGC 2636
Query: 355 TDGLVPSAAG 364
G + G
Sbjct: 2637 PQGYFRAGQG 2646
Score = 136 bits (329), Expect = 2e-31
Identities = 122/399 (30%), Positives = 155/399 (38%), Gaps = 60/399 (15%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD--VNEC--EIVDGVC-G 172
+V+EC A PGLC G C N++G F C C G+ + C D C + G C G
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAG 306
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDE------CADNDALCRGGRCVNTAGSFR 226
D H T C + A ++C CA L G +
Sbjct: 307 DLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGF 366
Query: 227 CECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
G G L P RL+ D GI S G + +GT A
Sbjct: 367 GSNGMGPPLGPARLNPHGSD----ARGIPSLGPGNSNIGT---------ATLNQTIDICR 413
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT 346
RC + TP SY C C G+ G C D+DEC + PC G C N
Sbjct: 414 HFTNLCLNGRC----LPTPSSYRCECNVGYTQDVRG-ECIDVDECT--SSPCHHGDCVNI 466
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
G+Y C C G A + C D+DEC ++S LC G
Sbjct: 467 PGTYHCQCYPGF--QATPTRQACVDVDEC--IVS------------------GGLCHLGR 504
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C NT GSF C C G+ + P+ G C D +EC T + C+N GSF C C+ G+
Sbjct: 505 CVNTEGSFQCVCNAGFELSPD-GKNCVDHNECATSTMCVNGV--CLNEDGSFSCLCKPGF 561
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
G C D+DEC T G C NT+GSFRC C
Sbjct: 562 LLAPGGHYCMDIDECQT--PGICVNGHCTNTEGSFRCQC 598
Score = 136 bits (328), Expect = 3e-31
Identities = 87/241 (36%), Positives = 105/241 (43%), Gaps = 39/241 (16%)
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
ID C C G+C T SY C C G G C D+DEC
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE---CIDVDECTS---------- 455
Query: 388 DELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
P C G C N G++ CQC G+ P + AC D DEC + CH
Sbjct: 456 -------SP-----CHHGDCVNIPGTYHCQCYPGFQATPTR-QACVDVDECIVSGGLCH- 501
Query: 448 AADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
C+N GSFQC C G+ DG C D +EC T+ C C N DGSF CLC
Sbjct: 502 LGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM-C-VNGVCLNEDGSFSCLCKP 559
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G+ G + C+DIDEC P +C NGHC+NT G + C C G DGR C
Sbjct: 560 GFLLAPGG-------HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC 611
Query: 566 L 566
+
Sbjct: 612 V 612
Score = 83.4 bits (197), Expect = 2e-15
Identities = 117/458 (25%), Positives = 154/458 (33%), Gaps = 54/458 (11%)
Query: 136 NLLGG-FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKAD 194
N+ G F C PG+ CV I CG+G C C C G A
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV----VPICRRACGEGFCSQPN---LCTCADGTLAP 110
Query: 195 D--FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM--ELAPDRLSCKDIDECSI 250
S+ C N CRG C+ G CG + + C + C+
Sbjct: 111 SCGVSRGSGCSVSCM-NGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCAC 169
Query: 251 TSGICSNGACENQMGTYQC---VCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
G CE T C V EG C P
Sbjct: 170 VYGFMGP-QCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQ 228
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSAAGA 365
H CR G+ +C+D+DEC C GG C N VGS+ C C G L S+A
Sbjct: 229 PH-PCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 366 KP----TCQDI---DECA-DLIS--TIIMMSVDELQKSVDPQIPELC---GAGSCHNTIG 412
+ C + CA DL T D + +PELC G+
Sbjct: 288 EDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCA 347
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP-AADCINLPGSFQCRCRDGWRGDGA 471
+ P + P ++ LG +P +D +P G
Sbjct: 348 QRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQ 407
Query: 472 TCEDVDECLTN---NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
T D+ TN NG C P T S+RC C+ GY D G C+D+DE
Sbjct: 408 TI-DICRHFTNLCLNGRCLP------TPSSYRCECNVGYTQDVRG--------ECIDVDE 452
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C + P C +G C N PG Y C C GF ++C+
Sbjct: 453 CTSSP--CHHGDCVNIPGTYHCQCYPGFQATPTRQACV 488
Score = 47.6 bits (108), Expect = 1e-04
Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Query: 4 GRCSGPLPTDVLRAVCCCSAL-GKAWGNQRCEPCPKKGTDAYQNLC 48
G+CS P + + CCCS G+ WG+ CE CP++G+ A+Q LC
Sbjct: 2024 GKCSVPKAFNTTKTRCCCSKRPGEGWGDP-CELCPQEGSAAFQELC 2068
Score = 46.0 bits (104), Expect = 4e-04
Identities = 20/35 (57%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V RA CCC G+ WG RCE CP GT AY+ LC
Sbjct: 2319 VTRAECCCGG-GRGWG-PRCELCPLPGTSAYRKLC 2351
Score = 36.3 bits (80), Expect = 0.29
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C LP VCCCS +G WG + CE CP + + +LC
Sbjct: 926 CGVTLPGKYRMDVCCCS-IGAVWGVE-CEACPDPESLEFASLC 966
>AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 433 bits (1067), Expect = e-121
Identities = 195/449 (43%), Positives = 251/449 (55%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC FPGLC HG CRN +G F C C G+ D++ C D++EC I +CG G C
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY++ K C+D+DECA + LC GG C NT GS++C+C G EL
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHELT 1105
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+C+DIDECS++ G+C +G C N +G +QC C G+ + +
Sbjct: 1106 AKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGG 1165
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C C+NT GSY C+C +G+ L DGR+C D+DEC R C G C N G + C C D
Sbjct: 1166 CDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYD 1225
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A TC D+DEC DL P +C G C NT GSFVC
Sbjct: 1226 GFM--ATPDMRTCVDVDEC-DL-------------------NPHICLHGDCENTKGSFVC 1263
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GY V+ + C+D DECE+G +C A C+N+PGSF CRC GW GDG C D+
Sbjct: 1264 HCQLGYMVR-KGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDL 1322
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC++ C PR C N GS+RC C G+ GDG + C D DECA + LC
Sbjct: 1323 DECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDG---------FFCEDRDECAENVDLC 1373
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+NG C N PGGY C+C++GF D R+C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRAC 1402
Score = 299 bits (734), Expect = 2e-80
Identities = 162/454 (35%), Positives = 214/454 (47%), Gaps = 42/454 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+V+ECA P LC G C N G + C C PG+E +K C D++EC + DG+C G C
Sbjct: 1070 MDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQC 1129
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G+F C C G+++ + CVDI+EC + C C+NT GS+RC CG G L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC-DVHCINTEGSYRCSCGQGYSLM 1188
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
PD +C D+DEC +C G C N G ++C+C +G+ +
Sbjct: 1189 PDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHI 1248
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTC 354
C H C NT GS+ C C+ G+ +R C D+DEC G C C N GS++C C
Sbjct: 1249 CLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRC 1308
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G V G C D+DEC + P+ G C N GS+
Sbjct: 1309 LPGWV----GDGFECHDLDECV------------SQEHRCSPR-------GDCLNVPGSY 1345
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C C G++ G C D DEC D C+N PG ++C C G+ D
Sbjct: 1346 RCTCRQGFA---GDGFFCEDRDEC-AENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRA 1401
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C+DVDEC G +C N G FRC+C+ GY+ D G +C DI+ECA D
Sbjct: 1402 CQDVDECA--QGNLCAFGSCENLPGMFRCICNGGYELDRGG-------GNCTDINECA-D 1451
Query: 533 PTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P C NG C NTPG Y C C F G C+
Sbjct: 1452 PVNCINGVCINTPGSYLCSCPQDFELNPSGVGCV 1485
Score = 259 bits (634), Expect = 2e-68
Identities = 181/571 (31%), Positives = 248/571 (43%), Gaps = 70/571 (12%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
+G CS + V RA CCCS LG+AWGN CE CP T Y+ LC G PN+
Sbjct: 1502 SGISCSAEIGVGVTRASCCCS-LGRAWGNP-CELCPMANTTEYRTLCPG-GEGFQPNR-- 1556
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNE 121
+T I + DE + G G + +++E
Sbjct: 1557 ------ITVILEDI--DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDE 1608
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C-EIVDGVCGDGDCHN 178
C+ +CG G C N LG +TC C Y + + + C+D+ + C +G C + N
Sbjct: 1609 CSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFN 1668
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
C C +++ C + C + C N A F + G L
Sbjct: 1669 VTRKMCC-CSYNI-GQAWNRPC---EACPTPISPDYQILCGNQAPGFLTDIHTGKPL--- 1720
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
DIDEC IC+NG C NQ+G+++C C G+ +++ CQ
Sbjct: 1721 -----DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 299 HS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
+ C+N PGSY C C G+ L + G +C +EC C G C +T GSY C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKL-SPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHR 1834
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G SA + C DIDEC D Q P CG G+C N IGS+ C
Sbjct: 1835 GFQASAD--QTLCMDIDEC-------------------DRQ-P--CGNGTCKNIIGSYNC 1870
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCE 474
C G+ V C D DEC C+N GSF C C+DG+ DG C
Sbjct: 1871 LCFPGFVVT--HNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCV 1928
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D +ECL+ G C P TC N +GSFRC+C G++ C+DIDEC+ +P
Sbjct: 1929 DTNECLSLAGTCLP-GTCQNLEGSFRCICPPGFQVQSD---------HCIDIDECSEEPN 1978
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
LC G C+N+PG ++C C GF + +G C
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 258 bits (633), Expect = 3e-68
Identities = 163/475 (34%), Positives = 220/475 (46%), Gaps = 73/475 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGD 175
++++EC P +C +G C N +G F C+C G+ +S C DV+EC + C + D
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C GYK CV +EC + +C G C++T GS+ C C G +
Sbjct: 1780 CINIPGSYRCKCTRGYKLSP-GGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D+ C DIDEC C NG C+N +G+Y C+C G+ +
Sbjct: 1839 SADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+ C+NT GS+HC C++G+ L ADG++C D +EC A C G C+N GS+ C C
Sbjct: 1897 VCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCIC 1956
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + C DIDEC+ + P LC G+C N+ GSF
Sbjct: 1957 PPGFQVQS----DHCIDIDECS--------------------EEPNLCLFGTCTNSPGSF 1992
Query: 415 VCQCPDGYSVKPEQGPACTDDDE--C----ELGTCDCHPAAD-------CINLPG----- 456
C CP G+ V + G C D + C E G C A + C PG
Sbjct: 1993 QCLCPPGF-VLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGD 2051
Query: 457 -----------SFQCRCRDGW---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+FQ C G G + EDV+EC N G C C NTDGSFRC
Sbjct: 2052 PCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVC-TNGVCVNTDGSFRCE 2110
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECA-NDPTLCENGHCSNTPGGYECDCDVGF 556
C GY D G+ +CVD DEC+ P C G C+N GG+EC C GF
Sbjct: 2111 CPFGYSLDFTGI-------NCVDTDECSVGHP--CGQGTCTNVIGGFECACADGF 2156
Score = 258 bits (631), Expect = 5e-68
Identities = 169/524 (32%), Positives = 227/524 (43%), Gaps = 36/524 (6%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRC-EPCPKKGTDAYQNLCIAVGTLLPPNQWD 61
GGRC+G L R CCC G+ W E CP +G++ +Q LC LLP +
Sbjct: 301 GGRCAGDLAGHYTRRQCCCDR-GRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGL 359
Query: 62 RPIDGNMTDIWSQVGGDENGDGYGKQWGE-NXXXXXXXXXXXXXXXXXXXXXXXXQMEVN 120
P +G NG G N ++
Sbjct: 360 FP---------GLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTID 410
Query: 121 ECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTE 180
C F LC +GRC + C+C GY +D + C+DV+EC C GDC N
Sbjct: 411 ICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDEC--TSSPCHHGDCVNIP 467
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
G++ C C PG++A + CVD+DEC + LC GRCVNT GSF+C C G EL+PD
Sbjct: 468 GTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+C D +EC+ TS +C NG C N+ G++ C+C G+ + +
Sbjct: 528 NCVDHNECA-TSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH 586
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCR----NTVGSYTCTCTD 356
C NT GS+ C C G + DGR C D + G C TV C C +
Sbjct: 587 CTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCAN 646
Query: 357 GLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
P +P CQ + E L S+ + ++ D + PE+C G C N
Sbjct: 647 ---PDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR 702
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GD 469
GS+ C C GY G CTD DEC L + C C N PGS+ C C G+ D
Sbjct: 703 GSYRCVCNLGYEA-GASGKDCTDVDECALNSLLCDNGW-CQNSPGSYSCSCPPGFHFWQD 760
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
C+DVDECL++ C C N GS+ C C G + D G
Sbjct: 761 TEICKDVDECLSS--PC-VSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 251 bits (614), Expect = 6e-66
Identities = 155/466 (33%), Positives = 208/466 (44%), Gaps = 32/466 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC P +C G C N+ GG C C+ G+ TCVDV+EC++ +C GDC
Sbjct: 1196 DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCE 1255
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC+ GY + C D+DEC C C+N GSF C C G
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--V 1313
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D C D+DEC CS G C N G+Y+C C +G+A
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL- 1372
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C + C+N PG Y C C G+ D R+C+D+DECA G C G C N G + C C
Sbjct: 1373 -CDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQG-NLCAFGSCENLPGMFRCIC 1430
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTI--IMMSVDELQKSVDPQIPEL--CGAGSCHNT 410
G G C DI+ECAD ++ I + ++ PQ EL G G
Sbjct: 1431 NGGYELDRGGG--NCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTR 1488
Query: 411 IGSFVCQCPD----GYSVKPEQGPACTDDD-ECELGTCDCHPAADC-INLPGSFQCRC-- 462
G+ + D G S E G T C LG +P C + ++ C
Sbjct: 1489 AGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPG 1548
Query: 463 RDGWRGDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
+G++ + T ED+DEC G C C NT GSF+C C GY +
Sbjct: 1549 GEGFQPNRITVILEDIDECQELPGLCQ-GGDCVNTFGSFQCECPPGYHLSEH-------T 1600
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DIDEC+ ++C G C NT G Y C C + + G +C+
Sbjct: 1601 RICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCM 1646
Score = 247 bits (604), Expect = 9e-65
Identities = 156/461 (33%), Positives = 199/461 (43%), Gaps = 31/461 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNECA PG+C +G C N G F C+C GY D CVD +EC V CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCT 2142
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G F C C G++ C DIDEC+ N LC RC NT GS+ C C G L
Sbjct: 2143 NVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLC-AFRCHNTEGSYLCTCPAGYTLRE 2200
Query: 238 DRLSCKDIDECSITSGIC-SNG-ACENQMGTYQCVCDEGYAQSTVKSHX-XXXXXXXXXX 294
D C+D+DEC+ C + G C+N +GT+ CVC G
Sbjct: 2201 DGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQP 2260
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN-TVGSYTC 352
C + CVNT GS+ C C EG+ C DI + A CR+ + S
Sbjct: 2261 DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVL-QTMCRSLSSSSEAV 2319
Query: 353 TCTDGLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
T + G P C+ L + + + LC G C
Sbjct: 2320 TRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGEC 2379
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW- 466
N++GSF C C GY+ C D DEC C C N GSF C C G+
Sbjct: 2380 INSLGSFRCHCQAGYT-PDATATTCLDMDECSQVPKPC--TFLCKNTKGSFLCSCPRGYL 2436
Query: 467 -RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
DG TC+D+DEC + C + C NT G+F C C G+ +C D
Sbjct: 2437 LEEDGRTCKDLDECTSRQHNC--QFLCVNTVGAFTCRCPPGFTQHH---------QACFD 2485
Query: 526 IDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DEC+ P C +GHC NTPG + C+C GFT + G C
Sbjct: 2486 NDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGC 2526
Score = 243 bits (594), Expect = 2e-63
Identities = 157/448 (35%), Positives = 205/448 (45%), Gaps = 74/448 (16%)
Query: 157 TCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI-----------DE 205
TC DVNECE GVC +G C NT GSF C C G D ++CVD+ DE
Sbjct: 866 TCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDE 925
Query: 206 CADN-DALCRGGRCVNTAGSF---RCE-------------CGHGMELAP-DRLS----CK 243
C R C + G+ CE C G+ A D LS K
Sbjct: 926 CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYK 985
Query: 244 DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHSCV 302
D++EC + G+C++G C N +G++ C C G+A + + C Q +CV
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 303 NTPGSYHCTCREGWHLR-ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
NTPGS+ C C G+ ++C D+DECA C GG C NT GSY C C G +
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHELT 1105
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
A G C+DIDEC S+ + LC G C N IG+F C C G
Sbjct: 1106 AKGT--ACEDIDEC----------SLSD----------GLCPHGQCVNVIGAFQCSCHAG 1143
Query: 422 YSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVD 477
+ P++ C D +EC + G CD H CIN GS++C C G+ DG C DVD
Sbjct: 1144 FQSTPDR-QGCVDINECRVQNGGCDVH----CINTEGSYRCSCGQGYSLMPDGRACADVD 1198
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC N C + C N G RCLC G+ +RT CVD+DEC +P +C
Sbjct: 1199 ECEENPRVC-DQGHCTNMPGGHRCLCYDGFMATP-DMRT------CVDVDECDLNPHICL 1250
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
+G C NT G + C C +G+ C
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGC 1278
Score = 239 bits (586), Expect = 1e-62
Identities = 169/500 (33%), Positives = 218/500 (43%), Gaps = 87/500 (17%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC + P C HG C N+ G + C C+PG++ CVDV+EC + G+C G C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC 505
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NTEGSF C C G++ K CVD +ECA + +C G C+N GSF C C G LA
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATS-TMCVNGVCLNEDGSFSCLCKPGFLLA 564
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTY--QC-----------VCDEGYAQST---- 279
P C DIDEC T GIC NG C N G++ QC VC + + +ST
Sbjct: 565 PGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 280 --------------VKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
KS CQ + C G + DGR
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 326 RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
DI+ECA C G C N GSY C C G A+G C D+DECA
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKD--CTDVDECA--------- 729
Query: 386 SVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
++ L LC G C N+ GS+ C CP G+ + C D DEC C
Sbjct: 730 -LNSL----------LCDNGWCQNSPGSYSCSCPPGFHFWQDT-EICKDVDECLSSPC-- 775
Query: 446 HPAADCINLPGSFQCRCRDGWRGD--GATCED---------VDE--CLTNNGGCHPRATC 492
+ C NL GS+ C+C G R D G C D + E C N G R+ C
Sbjct: 776 -VSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSEC 834
Query: 493 ANTDGSF------RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG 546
T G+ RC D G+ T +C D++EC + P +C NG C NT G
Sbjct: 835 CATLGAAWGSPCERCEIDPAC-ARGFARMTGV---TCDDVNECESFPGVCPNGRCVNTAG 890
Query: 547 GYECDCDVGFTRAADGRSCL 566
+ C+C G A GR C+
Sbjct: 891 SFRCECPEGLMLDASGRLCV 910
Score = 239 bits (584), Expect = 2e-62
Identities = 154/457 (33%), Positives = 206/457 (45%), Gaps = 63/457 (13%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG-D 175
+++EC+ P LC RC N G + C C GY C DV+EC C G +
Sbjct: 2166 DIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGME 2224
Query: 176 CHNTEGSFTCHCRPGYKADDFS-KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C N G+F C C PG + S + C D +EC LC GRCVNTAGSFRC+C G +
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 235 LAPDRLSCKDIDE----CSITSGICSNGACENQMGTY-QCVCDEGYAQSTVKSHXXXXXX 289
+P C DI + + +C + + ++ T +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGP---------- 2334
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
RC+ + +Y C G A+GR D+DEC A C G+C N++GS
Sbjct: 2335 ------RCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLCAHGECINSLGS 2385
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
+ C C G P A TC D+DEC+ Q+P+ C C N
Sbjct: 2386 FRCHCQAGYTPDATAT--TCLDMDECS--------------------QVPKPC-TFLCKN 2422
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
T GSF+C CP GY ++ E G C D DEC +C C+N G+F CRC G+
Sbjct: 2423 TKGSFLCSCPRGYLLE-EDGRTCKDLDECTSRQHNCQFL--CVNTVGAFTCRCPPGFTQH 2479
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
C D DEC G C C NT GSFRC C G+ V + C D++EC
Sbjct: 2480 HQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGF-------TLVSSGHGCEDVNEC 2532
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ P C++G C N GGY C C GFT+ + C+
Sbjct: 2533 -DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCV 2567
Score = 231 bits (564), Expect = 7e-60
Identities = 159/484 (32%), Positives = 212/484 (43%), Gaps = 73/484 (15%)
Query: 118 EVNECAAFPGLCGHGR---CRNLLGGFTCDCFPGYEK-DSKNHTCVDVNECEIVDGVCGD 173
+V+ECA C H R C+NL+G F C C PG C D NEC +C +
Sbjct: 2207 DVDECADGQQDC-HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVN 2265
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDE--CADN--DALCRGGRCVNTAGS-FRCE 228
G C NT GSF C C G++ C DI + C +CR + A + C
Sbjct: 2266 GRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECC 2325
Query: 229 CGHGM------ELAP------DRLSC----------KDIDECSITSGICSNGACENQMGT 266
CG G EL P R C +D+DEC + + +C++G C N +G+
Sbjct: 2326 CGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGS 2385
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR 326
++C C GY + C C NT GS+ C+C G+ L DGR+C+
Sbjct: 2386 FRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK 2445
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
D+DEC C C NTVG++TC C G C D DEC+
Sbjct: 2446 DLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFTQH----HQACFDNDECSAQ-------- 2492
Query: 387 VDELQKSVDPQIPELCGA-GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
P CGA G CHNT GSF C+C G+++ G C D +EC+ G C
Sbjct: 2493 ------------PGPCGAHGHCHNTPGSFRCECHQGFTLV-SSGHGCEDVNECD-GPHRC 2538
Query: 446 HPAADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N G ++C C G+ A C D +EC + C A+C NT G FRC+C
Sbjct: 2539 QHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGS-ASCRNTLGGFRCVC 2595
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGR 563
+G+ D + C D+DECA C C+NTPGG+ C C G+ RA G
Sbjct: 2596 PSGFDFDQ-------ALGGCQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQGH 2647
Query: 564 SCLG 567
G
Sbjct: 2648 CVSG 2651
Score = 230 bits (562), Expect = 1e-59
Identities = 165/510 (32%), Positives = 215/510 (42%), Gaps = 94/510 (18%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE--C--EIVDGVCG 172
++++EC+ P LC G C N G F C C PG+ H C D + C G C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCS 2027
Query: 173 DGDCHN-TEGSFTCHCRPGYKADD------------FSKIC--------------VDIDE 205
N T+ C RPG D F ++C D++E
Sbjct: 2028 VPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNE 2087
Query: 206 CADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMG 265
CA+N +C G CVNT GSFRCEC G L ++C D DECS+ C G C N +G
Sbjct: 2088 CAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-GHPCGQGTCTNVIG 2146
Query: 266 TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
++C C +G+ + + C C NT GSY CTC G+ LR DG C
Sbjct: 2147 GFECACADGFEPGLMMT-CEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMC 2205
Query: 326 RDIDECAGGARPC--GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
RD+DECA G + C G +C+N +G++ C C G+ P G+ C D +EC
Sbjct: 2206 RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRP-LPGSGEGCTDDNEC-------- 2256
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKP--------EQGPA---- 431
Q P+LC G C NT GSF C C +G+ P QGP
Sbjct: 2257 -----HAQ-------PDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Query: 432 ----C----TDDDECELGTCDC------HPAADCINLPGSFQCR--CRDGWRGDGATCED 475
C + + C C P + LPG+ R C G G A D
Sbjct: 2305 LQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG-SGYTAEGRD 2363
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
VDEC C C N+ GSFRC C GY D +C+D+DEC+ P
Sbjct: 2364 VDECRMLAHLC-AHGECINSLGSFRCHCQAGYTPD-------ATATTCLDMDECSQVPKP 2415
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C NT G + C C G+ DGR+C
Sbjct: 2416 C-TFLCKNTKGSFLCSCPRGYLLEEDGRTC 2444
Score = 229 bits (560), Expect = 2e-59
Identities = 151/465 (32%), Positives = 209/465 (44%), Gaps = 52/465 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C C GYE + C DV+EC + +C +G C
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQ 741
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N+ GS++C C PG+ ++IC D+DEC + C G C N AGS+ C+CG G L P
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDP 799
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
C D T G C E++ C+ ++++S C
Sbjct: 800 SGTFCLD-----STKGTCWLKIQESR-------CEVNLQGASLRSE-CCATLGAAWGSPC 846
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+ C P C G+ R G +C D++EC C G+C NT GS+ C C +G
Sbjct: 847 ER-CEIDP-----ACARGF-ARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEG 899
Query: 358 LVPSAAGAKPTCQDI-----------DECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
L+ A+G C D+ DEC + M D S+ C A
Sbjct: 900 LMLDASGR--LCVDVRLEPCFLRWDEDECGVTLPGKYRM--DVCCCSIGAVWGVECEACP 955
Query: 407 CHNTIGSFVCQCPDGYSVKPEQ----GPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
++ F CP G P D +EC++ C C N GSF C C
Sbjct: 956 DPESL-EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCAC 1013
Query: 463 RDGWRGDG--ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ D C D+DEC + C + TC NT GSF C C GY+ G+ L +
Sbjct: 1014 AGGFALDAQERNCTDIDECRISPDLC-GQGTCVNTPGSFECECFPGYE-SGFML-----M 1066
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+C+D+DECA DP LC G C+NT G Y+C C G A G +C
Sbjct: 1067 KNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 195 bits (475), Expect = 4e-49
Identities = 135/431 (31%), Positives = 183/431 (42%), Gaps = 60/431 (13%)
Query: 147 PGYEKDSKNHTCV---DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
PG E N V D++EC+ + G+C GDC NT GSF C C PGY + ++IC DI
Sbjct: 1547 PGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDI 1606
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC+ + ++C G C NT G++ C C +C D+ + NG C+N+
Sbjct: 1607 DECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNE 1664
Query: 264 MG----TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
+ C C Q+ + Q C N + G L
Sbjct: 1665 LAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDY---QILCGNQAPGFLTDIHTGKPL- 1720
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
DIDEC C G C N +GS+ C C G + C+D+DEC
Sbjct: 1721 -------DIDECGEIPAICANGICINQIGSFRCECPAGF--NYNSILLACEDVDECGSRE 1771
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC- 438
S Q++ D C N GS+ C+C GY + P G AC +EC
Sbjct: 1772 SPC--------QQNAD-----------CINIPGSYRCKCTRGYKLSP--GGACVGRNECR 1810
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTD 496
E+ H DC++ GS+ C C G++ D C D+DEC G TC N
Sbjct: 1811 EIPNVCSH--GDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG---NGTCKNII 1865
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN-DPTLCENGHCSNTPGGYECDCDVG 555
GS+ CLC G+ G CVD DEC +C GHC NT G + C C G
Sbjct: 1866 GSYNCLCFPGFVVTHNG--------DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDG 1917
Query: 556 FTRAADGRSCL 566
F ADG++C+
Sbjct: 1918 FELTADGKNCV 1928
Score = 168 bits (408), Expect = 5e-41
Identities = 88/250 (35%), Positives = 118/250 (47%), Gaps = 9/250 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC+ P C C+N G F C C GY + TC D++EC C C
Sbjct: 2404 LDMDECSQVPKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC-QFLC 2461
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G+FTC C PG+ + C D DEC+ C G C NT GSFRCEC G L
Sbjct: 2462 VNTVGAFTCRCPPGFT--QHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTL 2519
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
C+D++EC C +G C+NQ+G Y+C C +G+ Q + +
Sbjct: 2520 VSSGHGCEDVNECDGPHR-CQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPP 2577
Query: 296 RC-QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C SC NT G + C C G+ C+D+DECAG PC C NT G + C C
Sbjct: 2578 TCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPC-SYSCANTPGGFLCGC 2636
Query: 355 TDGLVPSAAG 364
G + G
Sbjct: 2637 PQGYFRAGQG 2646
Score = 136 bits (329), Expect = 2e-31
Identities = 122/399 (30%), Positives = 155/399 (38%), Gaps = 60/399 (15%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD--VNEC--EIVDGVC-G 172
+V+EC A PGLC G C N++G F C C G+ + C D C + G C G
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAG 306
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDE------CADNDALCRGGRCVNTAGSFR 226
D H T C + A ++C CA L G +
Sbjct: 307 DLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGF 366
Query: 227 CECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
G G L P RL+ D GI S G + +GT A
Sbjct: 367 GSNGMGPPLGPARLNPHGSD----ARGIPSLGPGNSNIGT---------ATLNQTIDICR 413
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT 346
RC + TP SY C C G+ G C D+DEC + PC G C N
Sbjct: 414 HFTNLCLNGRC----LPTPSSYRCECNVGYTQDVRG-ECIDVDECT--SSPCHHGDCVNI 466
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
G+Y C C G A + C D+DEC ++S LC G
Sbjct: 467 PGTYHCRCYPGF--QATPTRQACVDVDEC--IVS------------------GGLCHLGR 504
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C NT GSF C C G+ + P+ G C D +EC T + C+N GSF C C+ G+
Sbjct: 505 CVNTEGSFQCVCNAGFELSPD-GKNCVDHNECATSTMCVNGV--CLNEDGSFSCLCKPGF 561
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
G C D+DEC T G C NT+GSFRC C
Sbjct: 562 LLAPGGHYCMDIDECQT--PGICVNGHCTNTEGSFRCQC 598
Score = 134 bits (324), Expect = 8e-31
Identities = 86/241 (35%), Positives = 105/241 (43%), Gaps = 39/241 (16%)
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
ID C C G+C T SY C C G G C D+DEC
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE---CIDVDECTS---------- 455
Query: 388 DELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
P C G C N G++ C+C G+ P + AC D DEC + CH
Sbjct: 456 -------SP-----CHHGDCVNIPGTYHCRCYPGFQATPTR-QACVDVDECIVSGGLCH- 501
Query: 448 AADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
C+N GSFQC C G+ DG C D +EC T+ C C N DGSF CLC
Sbjct: 502 LGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM-C-VNGVCLNEDGSFSCLCKP 559
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G+ G + C+DIDEC P +C NGHC+NT G + C C G DGR C
Sbjct: 560 GFLLAPGG-------HYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC 611
Query: 566 L 566
+
Sbjct: 612 V 612
Score = 82.6 bits (195), Expect = 3e-15
Identities = 117/458 (25%), Positives = 154/458 (33%), Gaps = 54/458 (11%)
Query: 136 NLLGG-FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKAD 194
N+ G F C PG+ CV I CG+G C C C G A
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV----VPICRRACGEGFCSQPN---LCTCADGTLAP 110
Query: 195 D--FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM--ELAPDRLSCKDIDECSI 250
S+ C N CRG C+ G CG + + C + C+
Sbjct: 111 SCGVSRGSGCSVSCM-NGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCAC 169
Query: 251 TSGICSNGACENQMGTYQC---VCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
G CE T C V EG C P
Sbjct: 170 VYGFMGP-QCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQ 228
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSAAGA 365
H CR G+ +C+D+DEC C GG C N VGS+ C C G L S+A
Sbjct: 229 PH-PCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
Query: 366 KP----TCQDI---DECA-DLIS--TIIMMSVDELQKSVDPQIPELC---GAGSCHNTIG 412
+ C + CA DL T D + +PELC G+
Sbjct: 288 EDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCA 347
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP-AADCINLPGSFQCRCRDGWRGDGA 471
+ P + P ++ LG +P +D +P G
Sbjct: 348 QRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQ 407
Query: 472 TCEDVDECLTN---NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
T D+ TN NG C P T S+RC C+ GY D G C+D+DE
Sbjct: 408 TI-DICRHFTNLCLNGRCLP------TPSSYRCECNVGYTQDVRG--------ECIDVDE 452
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C + P C +G C N PG Y C C GF ++C+
Sbjct: 453 CTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACV 488
Score = 47.6 bits (108), Expect = 1e-04
Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Query: 4 GRCSGPLPTDVLRAVCCCSAL-GKAWGNQRCEPCPKKGTDAYQNLC 48
G+CS P + + CCCS G+ WG+ CE CP++G+ A+Q LC
Sbjct: 2024 GKCSVPKAFNTTKTRCCCSKRPGEGWGDP-CELCPQEGSAAFQELC 2068
Score = 46.0 bits (104), Expect = 4e-04
Identities = 20/35 (57%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V RA CCC G+ WG RCE CP GT AY+ LC
Sbjct: 2319 VTRAECCCGG-GRGWG-PRCELCPLPGTSAYRKLC 2351
Score = 36.3 bits (80), Expect = 0.29
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C LP VCCCS +G WG + CE CP + + +LC
Sbjct: 926 CGVTLPGKYRMDVCCCS-IGAVWGVE-CEACPDPESLEFASLC 966
>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
Length = 3002
Score = 429 bits (1056), Expect = e-119
Identities = 196/449 (43%), Positives = 253/449 (56%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NEC P LC HG+CRN +G F C C G+ DS+ C D++EC I +CG G C
Sbjct: 1159 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1218
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT G F C C GY++ K C+DIDEC + LCRGG C NT GS+RCEC G +L+
Sbjct: 1219 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS 1278
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
P+ +C DI+EC +++ +C NG C N +G YQC C+ GY + +
Sbjct: 1279 PNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGG 1338
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C+ C N+ GSY C+C+ G+ L D RSC DIDEC C GGQC N G Y C C D
Sbjct: 1339 CETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYD 1398
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A+ TC D++EC DL P +C +G+C NT GSF+C
Sbjct: 1399 GFM--ASEDMKTCVDVNEC-DL-------------------NPNICLSGTCENTKGSFIC 1436
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GYS K + CTD +ECE+G +C A C N GSF+C C GW GDG C D+
Sbjct: 1437 HCDMGYSGKKGK-TGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDL 1495
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC C A C NT GS+RCLC GY GDG ++C D+DEC+ + LC
Sbjct: 1496 DECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDG---------FTCTDLDECSENLNLC 1546
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
NG C N PGGY C+CD+GF +ADG++C
Sbjct: 1547 GNGQCLNAPGGYRCECDMGFVPSADGKAC 1575
Score = 301 bits (740), Expect = 3e-81
Identities = 165/445 (37%), Positives = 219/445 (49%), Gaps = 44/445 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+++EC P LC G C N G + C+C PG++ C+D+NECE+ +C +G C
Sbjct: 1243 MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRC 1302
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G + C C PGY + CVDIDEC+ + C C N+ GS+ C C G L
Sbjct: 1303 VNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCE-TFCTNSEGSYECSCQPGFALM 1361
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXX 295
PD+ SC DIDEC IC G C N G Y+C+C +G+ A +K+
Sbjct: 1362 PDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNI 1421
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTC 354
+C NT GS+ C C G+ + C DI+EC GA CG C NT GS+ C+C
Sbjct: 1422 CLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSC 1481
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGS 413
+ G + G K C D+DEC++ T +C C NT+GS
Sbjct: 1482 SPGWI--GDGIK--CTDLDECSN--GT------------------HMCSQHADCKNTMGS 1517
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGA 471
+ C C +GY+ G CTD DEC C C+N PG ++C C G+ DG
Sbjct: 1518 YRCLCKEGYT---GDGFTCTDLDECSENLNLC-GNGQCLNAPGGYRCECDMGFVPSADGK 1573
Query: 472 TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
CED+DEC N TC N G FRC C+ GY+ D G +C D++EC
Sbjct: 1574 ACEDIDECSLPN--ICVFGTCHNLPGLFRCECEIGYELDRSG-------GNCTDVNECL- 1623
Query: 532 DPTLCENGHCSNTPGGYECDCDVGF 556
DPT C +G+C NTPG Y CDC F
Sbjct: 1624 DPTTCISGNCVNTPGSYICDCPPDF 1648
Score = 291 bits (714), Expect = 4e-78
Identities = 172/506 (33%), Positives = 238/506 (47%), Gaps = 70/506 (13%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++NEC LC +GRC NL+G + C C PGY CVD++EC I++G C + C
Sbjct: 1285 IDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGC-ETFC 1343
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N+EGS+ C C+PG+ + C DIDEC DN +C GG+C N G +RC C G +
Sbjct: 1344 TNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMAS 1403
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
D +C D++EC + IC +G CEN G++ C CD GY+ K+
Sbjct: 1404 EDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHN 1463
Query: 297 C-QHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCT 353
C +H+ C NT GS+ C+C GW DG C D+DEC+ G C C+NT+GSY C
Sbjct: 1464 CGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL 1521
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTI-------------------IMMSVD-ELQKS 393
C +G G TC D+DEC++ ++ + S D + +
Sbjct: 1522 CKEGYT----GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACED 1577
Query: 394 VDP-QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCI 452
+D +P +C G+CHN G F C+C GY + G CTD +EC L C + +C+
Sbjct: 1578 IDECSLPNICVFGTCHNLPGLFRCECEIGYELD-RSGGNCTDVNEC-LDPTTCI-SGNCV 1634
Query: 453 NLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCH----PRA-----TCANTDG----SF 499
N PGS+ C C + + VD T +G C+ PR C+N G
Sbjct: 1635 NTPGSYICDCPPDFELNPTRVGCVD---TRSGNCYLDIRPRGDNGDTACSNEIGVGVSKA 1691
Query: 500 RCLCDTG-----------------YK---GDGYGLRTVCCVYSCVDIDECANDPTLCENG 539
C C G YK G G R DIDEC P LC+ G
Sbjct: 1692 SCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGG 1751
Query: 540 HCSNTPGGYECDCDVGFTRAADGRSC 565
C NT G ++C C G+ D R C
Sbjct: 1752 KCINTFGSFQCRCPTGYYLNEDTRVC 1777
Score = 255 bits (624), Expect = 4e-67
Identities = 184/548 (33%), Positives = 232/548 (42%), Gaps = 82/548 (14%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWDRPID 65
CS + V +A CCCS LGKAWG CE CP T Y+ LC G PN PI
Sbjct: 1680 CSNEIGVGVSKASCCCS-LGKAWGTP-CEMCPAVNTSEYKILCPG-GEGFRPN----PIT 1732
Query: 66 GNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNECAAF 125
+ DI DE + G G +VNEC
Sbjct: 1733 VILEDI------DECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET- 1785
Query: 126 PGLCGHGRCRNLL---------------GGFTCD------CFPGYEKDS----------- 153
PG+CG G C N + GG C C+ Y D+
Sbjct: 1786 PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNM 1845
Query: 154 -KNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC---RPGYKADDFSKICVDIDECADN 209
K C N + C +T+ F C RPG+ D ++ + VDIDEC +
Sbjct: 1846 TKKMCCCSYNIGRAWNKPCEQCPIPSTD-EFATLCGSQRPGFVIDIYTGLPVDIDECREI 1904
Query: 210 DALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQ 268
+C G C+N GSFRCEC G L C+DIDEC +C N C N G+Y+
Sbjct: 1905 PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECINTAGSYR 1963
Query: 269 CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH-SCVNTPGSYHCTCREGWHLRADGRSCRD 327
C C GY + T C H C++T GS++C C G+ D C D
Sbjct: 1964 CDCKPGY-RFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLD 2022
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
I+EC A CG G CRNT+GS+ C C G + S C D+DECA
Sbjct: 2023 INECERDA--CGNGTCRNTIGSFNCRCNHGFILS---HNNDCIDVDECAS---------- 2067
Query: 388 DELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
LC G C NT+GSF CQC +GY V P+ G C D +EC L C P
Sbjct: 2068 ---------GNGNLCRNGQCINTVGSFQCQCNEGYEVAPD-GRTCVDINECLLEPRKCAP 2117
Query: 448 AADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
C NL GS++C C G+ CED+DEC+ C TC+NT+GSF+CLC G+
Sbjct: 2118 GT-CQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEIC-ALGTCSNTEGSFKCLCPEGF 2175
Query: 508 KGDGYGLR 515
G R
Sbjct: 2176 SLSSSGRR 2183
Score = 254 bits (623), Expect = 5e-67
Identities = 152/452 (33%), Positives = 218/452 (48%), Gaps = 53/452 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC PG+C +G C N++G F C+C G+ + K C D++EC+ + +C
Sbjct: 1896 VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC 1955
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS+ C C+PGY+ + C D +EC + +C G+C++T GSF C C G +
Sbjct: 1956 INTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTN 2014
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
D+ C DI+EC + C NG C N +G++ C C+ G+ S
Sbjct: 2015 DDQTMCLDINECERDA--CGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNL 2072
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
C++ C+NT GS+ C C EG+ + DGR+C DI+EC R C G C+N GSY C C
Sbjct: 2073 CRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICP 2132
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G S K C+DIDEC V+E PE+C G+C NT GSF
Sbjct: 2133 PGY--SLQNEK--CEDIDEC-----------VEE---------PEICALGTCSNTEGSFK 2168
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCED 475
C CP+G+S+ G C D + C + P S R+ + + C
Sbjct: 2169 CLCPEGFSLS-SSGRRCQD---LRMSYCYAKFEGGKCSSPKS-----RNHSKQE-CCC-- 2216
Query: 476 VDECLTNNGGCHPRATC-ANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
L G P C D +FR +C G G G S VD+DEC +P
Sbjct: 2217 ---ALKGEGWGDPCELCPTEPDEAFRQICPYG-SGIIVGPDD-----SAVDMDEC-KEPD 2266
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C++G C NT G Y C+C G+T A G C+
Sbjct: 2267 VCKHGQCINTDGSYRCECPFGYTLA--GNECV 2296
Score = 250 bits (612), Expect = 1e-65
Identities = 156/466 (33%), Positives = 209/466 (44%), Gaps = 73/466 (15%)
Query: 134 CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKA 193
C+NL+G + C C PGY++ CVD NEC+ G+C +G C NT GS+TC C G+ A
Sbjct: 2396 CKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTA 2455
Query: 194 DDFSKICVDIDE--CADN--DALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCK----- 243
C+D E C +C+ G N C C G P C
Sbjct: 2456 SPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTV 2515
Query: 244 -----------------DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
DIDEC + +C NG C N G+Y C+C GY +
Sbjct: 2516 AFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVD 2575
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT 346
C C NT GSY C+C +G+ L+ DGRSC+D+DECA C C NT
Sbjct: 2576 LNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF-LCVNT 2634
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-G 405
+G +TC C G +C D +EC I+ LCG+ G
Sbjct: 2635 IGGFTCKCPPGFTQHHT----SCIDNNECTSDIN--------------------LCGSKG 2670
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C NT GSF C+C G+S+ + G +C D DECE G C C N+ G ++C C G
Sbjct: 2671 ICQNTPGSFTCECQRGFSLD-QTGSSCEDVDECE-GNHRCQHG--CQNIIGGYRCSCPQG 2726
Query: 466 W--RGDGATCEDVDECLTNN--GGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
+ C D +ECL+ + GG A+C NT GS++C+C G++ + +
Sbjct: 2727 YLQHYQWNQCVDENECLSAHICGG----ASCHNTLGSYKCMCPAGFQYEQFS-------G 2775
Query: 522 SCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
C DI+EC + C G CSNT GGY C C G+ R G G
Sbjct: 2776 GCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGYFRIGQGHCVSG 2820
Score = 246 bits (601), Expect = 2e-64
Identities = 157/466 (33%), Positives = 210/466 (45%), Gaps = 43/466 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC P +C HG+C N G + C+C GY + CVD +EC V CG+G C
Sbjct: 2257 VDMDECKE-PDVCKHGQCINTDGSYRCECPFGY--TLAGNECVDTDECS-VGNPCGNGTC 2312
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G F C C G++ C DI+ECA N LC RCVNT GS+ C+C G L
Sbjct: 2313 KNVIGGFECTCEEGFEPGPM-MTCEDINECAQNPLLC-AFRCVNTYGSYECKCPVGYVLR 2370
Query: 237 PDRLSCKDIDECSITSGICSNG--ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
DR CKD DEC C+ C+N +GTY C+C GY +
Sbjct: 2371 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2430
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDE--CAGGA--RPCG-GGQCRNTVG 348
C++ C+NT GSY C C +G+ + C D E C C G RN V
Sbjct: 2431 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT 2490
Query: 349 SYTCTCTDGLVPSAAGAKPTCQDID-ECADLISTIIMMSVDELQKSVD----PQIPELCG 403
C C G G P C+ + + + D I ++C
Sbjct: 2491 KSECCCDGG-----RGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCR 2545
Query: 404 AGSCHNTIGSFVCQCPDGYSVKPE-QGPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
G C N GS+ C C GY+ P+ G +C D +EC C+ C N GS+QC C
Sbjct: 2546 NGECVNDRGSYHCICKTGYT--PDITGTSCVDLNECNQAPKPCN--FICKNTEGSYQCSC 2601
Query: 463 RDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ + DG +C+D+DEC T C + C NT G F C C G+
Sbjct: 2602 PKGYILQEDGRSCKDLDECATKQHNC--QFLCVNTIGGFTCKCPPGFTQHH--------- 2650
Query: 521 YSCVDIDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
SC+D +EC +D LC G C NTPG + C+C GF+ G SC
Sbjct: 2651 TSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSC 2696
Score = 245 bits (600), Expect = 3e-64
Identities = 155/471 (32%), Positives = 212/471 (45%), Gaps = 42/471 (8%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC P +C G+C N+ G + C C+ G+ TCVDVNEC++ +C G C
Sbjct: 1369 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCE 1428
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC GY C DI+EC C + C NTAGSF+C C G
Sbjct: 1429 NTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW--I 1486
Query: 237 PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D + C D+DECS + +CS A C+N MG+Y+C+C EGY
Sbjct: 1487 GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTC--TDLDECSENLN 1544
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C + C+N PG Y C C G+ ADG++C DIDEC+ C G C N G + C C
Sbjct: 1545 LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNLPGLFRCEC 1603
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPEL--------C---G 403
G +G C D++EC D + I V+ + P+ C
Sbjct: 1604 EIGYELDRSGGN--CTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTR 1661
Query: 404 AGSCHNTI------GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
+G+C+ I G C G V + C + C+ PA +
Sbjct: 1662 SGNCYLDIRPRGDNGDTACSNEIGVGVS--KASCCCSLGKAWGTPCEMCPAVNTSEY--K 1717
Query: 458 FQCRCRDGWRGDGATC--EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
C +G+R + T ED+DEC G C C NT GSF+C C TGY L
Sbjct: 1718 ILCPGGEGFRPNPITVILEDIDECQELPGLCQG-GKCINTFGSFQCRCPTGYY-----LN 1771
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
V C D++EC P +C G C NT G Y C C + + G +C+
Sbjct: 1772 EDTRV--CDDVNECET-PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCM 1819
Score = 243 bits (595), Expect = 1e-63
Identities = 139/394 (35%), Positives = 190/394 (48%), Gaps = 22/394 (5%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C LC +GRC G + C+C G++ D + C+DV+ECE C G+C N +G
Sbjct: 584 CQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGE-CIDVDECE--KNPCAGGECINNQG 640
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
S+TC CR GY++ C DIDEC N +C GRC+NT GSF C C G + D +
Sbjct: 641 SYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 700
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C+D+DECSI + +C NG C N+ G+++C+C G+ ++ + C
Sbjct: 701 CEDMDECSIRN-MCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRC 759
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDI---DECAGGARPCGGGQC-RNTVGSYT---CTC 354
VNT GSY C C G + DGR C D C GG + GQC + G+ T C C
Sbjct: 760 VNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYK---RGQCIKPLFGAVTKSECCC 816
Query: 355 TDGLVPSAAGAKP-TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
+P Q+ E L S+ M+ + P++C G C N G+
Sbjct: 817 ASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGT 876
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG--WRGDGA 471
+ C C GY V G C D +EC L + C C N PGSF C C G ++ D
Sbjct: 877 YKCICNSGYEV-DSTGKNCVDINECVLNSLLC-DNGQCRNTPGSFVCTCPKGFIYKPDLK 934
Query: 472 TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
TCED+DEC + C C N+ GSF C C +
Sbjct: 935 TCEDIDEC--ESSPC-INGVCKNSPGSFICECSS 965
Score = 240 bits (587), Expect = 1e-62
Identities = 155/461 (33%), Positives = 207/461 (44%), Gaps = 68/461 (14%)
Query: 117 MEVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA+ G LC +G+C N +G F C C GYE TCVD+NEC + C G
Sbjct: 2060 IDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGT 2119
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N +GS+ C C PGY + + C DIDEC + +C G C NT GSF+C C G L
Sbjct: 2120 CQNLDGSYRCICPPGYSLQN--EKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSL 2177
Query: 236 APDRLSCKDI--DEC--SITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ C+D+ C G CS+ N +C C +K
Sbjct: 2178 SSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNH-SKQECCC-------ALKGEGWGDP--- 2226
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWHLRAD-GRSCRDIDECAGGARPCGGGQCRNTVGSY 350
C+ ++ C G + S D+DEC C GQC NT GSY
Sbjct: 2227 -----CELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKE-PDVCKHGQCINTDGSY 2280
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNT 410
C C G + AG + C D DEC+ + CG G+C N
Sbjct: 2281 RCECPFGY--TLAGNE--CVDTDECS---------------------VGNPCGNGTCKNV 2315
Query: 411 IGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RG 468
IG F C C +G+ P C D +EC C A C+N GS++C+C G+ R
Sbjct: 2316 IGGFECTCEEGFEPGPMM--TCEDINECAQNPLLC--AFRCVNTYGSYECKCPVGYVLRE 2371
Query: 469 DGATCEDVDECLTNNGGC-HPRATCANTDGSFRCLCDTGY--KGDGYGLRTVCCVYSCVD 525
D C+D DEC C + C N G++ C+C GY + DG G CVD
Sbjct: 2372 DRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEG---------CVD 2422
Query: 526 IDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+EC P +CENG C NT G Y C+C+ GFT + + CL
Sbjct: 2423 ENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 2463
Score = 239 bits (584), Expect = 2e-62
Identities = 166/508 (32%), Positives = 224/508 (44%), Gaps = 94/508 (18%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDV-----------NECEI 166
+++EC + P C +G C+N G F C+C D C++ CEI
Sbjct: 938 DIDECESSP--CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEI 995
Query: 167 -VDGVCGDGDCHNTEGSF------TCH----CRPGYKADDFSKICVDIDECADNDALCRG 215
++G C ++ G+ C C GY ++ C DIDEC +C+
Sbjct: 996 NINGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQ-CEDIDECEVFPGVCKN 1054
Query: 216 GRCVNTAGSFRCECGHGMELAPDRLSCKDI-----------DECSITSG--------ICS 256
G CVNT GSF+C+C GM L C DI +EC++ CS
Sbjct: 1055 GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCS 1114
Query: 257 NGA------CEN----QMGTYQCVCDEG--YAQSTV---KSHXXXXXXXXXXXXRCQHS- 300
GA CE Y+ +C G +A + K C H
Sbjct: 1115 VGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGK 1174
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP 360
C NT GS+ C C G+ L ++ R+C DIDEC CG GQC NT G + C C +G
Sbjct: 1175 CRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYES 1234
Query: 361 SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD 420
K C DIDEC Q+ P LC G CHNT GS+ C+CP
Sbjct: 1235 GFMMMK-NCMDIDEC---------------QRD-----PLLCRGGVCHNTEGSYRCECPP 1273
Query: 421 GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDE 478
G+ + P AC D +ECEL C P C+NL G +QC C G+ D C D+DE
Sbjct: 1274 GHQLSPNIS-ACIDINECELSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1331
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN 538
C NGGC C N++GS+ C C G+ + SC DIDEC ++P +C+
Sbjct: 1332 CSIMNGGCE--TFCTNSEGSYECSCQPGFA-------LMPDQRSCTDIDECEDNPNICDG 1382
Query: 539 GHCSNTPGGYECDCDVGFTRAADGRSCL 566
G C+N PG Y C C GF + D ++C+
Sbjct: 1383 GQCTNIPGEYRCLCYDGFMASEDMKTCV 1410
Score = 239 bits (584), Expect = 2e-62
Identities = 153/480 (31%), Positives = 207/480 (43%), Gaps = 68/480 (14%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++ +EC+ CG+G C+N++GGF C C G+E TC D+NEC +C C
Sbjct: 2296 VDTDECSV-GNPCGNGTCKNVIGGFECTCEEGFEPGPMM-TCEDINECAQNPLLCAFR-C 2352
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC--RGGRCVNTAGSFRCECGHGME 234
NT GS+ C C GY + ++C D DEC + C + C N G++ C CG G +
Sbjct: 2353 VNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQ 2412
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
PD C D +EC GIC NG C N G+Y C C++G+ S +
Sbjct: 2413 RRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFT 2472
Query: 295 XRCQHSCV------NTPGSYHCTCR--EGW--------------------HLRADGRSCR 326
Q+ C N C C GW H R +
Sbjct: 2473 EVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA 2532
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
DIDEC C G+C N GSY C C G P G +C D++EC
Sbjct: 2533 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGT--SCVDLNECN---------- 2580
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCH 446
Q P+ C C NT GS+ C CP GY ++ E G +C D DEC +C
Sbjct: 2581 ----------QAPKPCNF-ICKNTEGSYQCSCPKGYILQ-EDGRSCKDLDECATKQHNCQ 2628
Query: 447 PAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
C+N G F C+C G+ +C D +EC ++ C + C NT GSF C C G
Sbjct: 2629 FL--CVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRG 2686
Query: 507 YKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ D G SC D+DEC + C++G C N GGY C C G+ + C+
Sbjct: 2687 FSLDQTG-------SSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQGYLQHYQWNQCV 2737
Score = 223 bits (546), Expect = 1e-57
Identities = 155/464 (33%), Positives = 202/464 (43%), Gaps = 47/464 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C C GYE DS CVD+NEC + +C +G C
Sbjct: 854 DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCR 913
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT GSF C C G+ K C DIDEC + C G C N+ GSF CEC L P
Sbjct: 914 NTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSSESTLDP 971
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
+ C G C + + C+ +T+KS C
Sbjct: 972 TKTIC-----IETIKGTCWQTVIDGR-------CEININGATLKSQ-CCSSLGAAWGSPC 1018
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
C P C +G+ R G C DIDEC C G C NT GS+ C C G
Sbjct: 1019 T-LCQVDP-----ICGKGYS-RIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSG 1071
Query: 358 LVPSAAGAKPTCQDI--DEC----ADLISTIIMMS---VDELQKSVDPQI-PELCGAGSC 407
+ A G C DI + C D T+ + +D SV E C
Sbjct: 1072 MTLDATGR--ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPM 1129
Query: 408 HNTIG-SFVCQCPDGYSVK--PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
NT +C G++ K P D +EC++ C C N GSF+CRC
Sbjct: 1130 RNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLC-THGKCRNTIGSFKCRCDS 1188
Query: 465 GWRGDG--ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ D C D+DEC + C R C NT G F C CD GY+ G+ + + +
Sbjct: 1189 GFALDSEERNCTDIDECRISPDLC-GRGQCVNTPGDFECKCDEGYE-SGFMM-----MKN 1241
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C+DIDEC DP LC G C NT G Y C+C G + + +C+
Sbjct: 1242 CMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACI 1285
Score = 215 bits (525), Expect = 3e-55
Identities = 153/467 (32%), Positives = 198/467 (42%), Gaps = 63/467 (13%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC +C +GRC N G F C C G+ C D++EC I +C +G C
Sbjct: 661 DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI-RNMCLNGMCI 719
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N +GSF C C+PG++ + C DI+EC + +C GRCVNT GS+RCEC G+ +
Sbjct: 720 NEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRCECFPGLAVGL 778
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
D C D S G G QC+ + + KS C
Sbjct: 779 DGRVCVDTHMRSTCYGGYKRG---------QCI--KPLFGAVTKSECCCASTEYAFGEPC 827
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
Q Y C G + + G DI+ECA C G C N G+Y C C G
Sbjct: 828 QPCPAQNSAEYQALCSSGPGMTSAG---SDINECALDPDICPNGICENLRGTYKCICNSG 884
Query: 358 LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQ 417
+ G C DI+EC ++ S+ LC G C NT GSFVC
Sbjct: 885 YEVDSTG--KNCVDINEC-------VLNSL-------------LCDNGQCRNTPGSFVCT 922
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD-------- 469
CP G+ KP+ C D DECE C C N PGSF C C D
Sbjct: 923 CPKGFIYKPDL-KTCEDIDECESSPC---INGVCKNSPGSFICECSSESTLDPTKTICIE 978
Query: 470 --GATCED--VD-ECLTNNGGCHPRATCANTDGS---FRC-LCDTG-YKGDGYGLRTVCC 519
TC +D C N G ++ C ++ G+ C LC G GY
Sbjct: 979 TIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGT- 1037
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DIDEC P +C+NG C NT G ++C C G T A GR CL
Sbjct: 1038 --QCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICL 1082
Score = 211 bits (516), Expect = 4e-54
Identities = 132/398 (33%), Positives = 177/398 (44%), Gaps = 36/398 (9%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GD 175
++NEC CG H C N G F C C PG+ D C D++EC +C D
Sbjct: 1453 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIK--CTDLDECSNGTHMCSQHAD 1510
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C NT GS+ C C+ GY D F+ C D+DEC++N LC G+C+N G +RCEC G
Sbjct: 1511 CKNTMGSYRCLCKEGYTGDGFT--CTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVP 1568
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C+DIDECS+ + IC G C N G ++C C+ GY +
Sbjct: 1569 SADGKACEDIDECSLPN-ICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTT 1627
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDI--DECAGGARPCGGG---QCRNTVG-- 348
+CVNTPGSY C C + L C D C RP G C N +G
Sbjct: 1628 CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVG 1687
Query: 349 --SYTCTCTDG--------LVP--SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDP 396
+C C+ G + P + + K C + T+I+ +DE Q
Sbjct: 1688 VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQ----- 1742
Query: 397 QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPG 456
++P LC G C NT GSF C+CP GY + E C D +ECE C P C N G
Sbjct: 1743 ELPGLCQGGKCINTFGSFQCRCPTGYYLN-EDTRVCDDVNECETPGI-CGPGT-CYNTVG 1799
Query: 457 SFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATC 492
++ C C + G C D+ L TC
Sbjct: 1800 NYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1837
Score = 203 bits (496), Expect = 1e-51
Identities = 140/422 (33%), Positives = 194/422 (45%), Gaps = 48/422 (11%)
Query: 157 TCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGG 216
+ VD++EC+ D VC G C NT+GS+ C C GY CVD DEC+ + C G
Sbjct: 2255 SAVDMDECKEPD-VCKHGQCINTDGSYRCECPFGYTLA--GNECVDTDECSVGNP-CGNG 2310
Query: 217 RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYA 276
C N G F C C G E P ++C+DI+EC+ +C+ C N G+Y+C C GY
Sbjct: 2311 TCKNVIGGFECTCEEGFEPGP-MMTCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYV 2368
Query: 277 QSTVKSHXXXXXXXXXXXXRC---QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAG 333
+ C Q C N G+Y C C G+ R DG C D +EC
Sbjct: 2369 LREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQT 2428
Query: 334 GARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKS 393
C G+C NT GSYTC C DG +A+ + C +D T ++ ++ ++ S
Sbjct: 2429 KPGICENGRCLNTRGSYTCECNDGF--TASPNQDEC--LDNREGYCFTEVLQNMCQIGSS 2484
Query: 394 -VDPQIPELC----GAG---SC-----HNTIGSFVCQCPDGYSVKPEQGPACTDDDECEL 440
+P C G G C T+ +F CP G D DEC++
Sbjct: 2485 NRNPVTKSECCCDGGRGWGPHCEICPFQGTV-AFKKLCPHGRGFMTNG----ADIDECKV 2539
Query: 441 GTCDCHPAADCINLPGSFQCRCRDGWRGD--GATCEDVDECLTNNGGCHPRATCANTDGS 498
C +C+N GS+ C C+ G+ D G +C D++EC C+ C NT+GS
Sbjct: 2540 IHDVCR-NGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN--FICKNTEGS 2596
Query: 499 FRCLCDTGY--KGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
++C C GY + DG SC D+DECA C+ C NT GG+ C C GF
Sbjct: 2597 YQCSCPKGYILQEDG---------RSCKDLDECATKQHNCQ-FLCVNTIGGFTCKCPPGF 2646
Query: 557 TR 558
T+
Sbjct: 2647 TQ 2648
Score = 201 bits (490), Expect = 6e-51
Identities = 144/478 (30%), Positives = 197/478 (41%), Gaps = 73/478 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++NEC LC +G+CRN G F C C G+ TC D++ECE C +G C
Sbjct: 895 VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECE--SSPCINGVC 952
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD----------ID-ECADN-DALCRGGRCVNTAGS 224
N+ GSF C C D IC++ ID C N + +C ++ G+
Sbjct: 953 KNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGA 1012
Query: 225 ------FRCE----CGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
C+ CG G C+DIDEC + G+C NG C N G+++C C G
Sbjct: 1013 AWGSPCTLCQVDPICGKGYSRIKG-TQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSG 1071
Query: 275 YAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG 334
R + +C CT R D C A G
Sbjct: 1072 M--------TLDATGRICLDIRLE-TCFLRYEDEECTLPIAGRHRMDACCCS--VGAAWG 1120
Query: 335 ARPCGGGQCRNTVGSYTCTCTDG---LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQ 391
C RNT Y C G KP +DI+EC
Sbjct: 1121 TEECEECPMRNT-PEYEELCPRGPGFATKEITNGKPFFKDINEC---------------- 1163
Query: 392 KSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
IP LC G C NTIGSF C+C G+++ E+ CTD DEC + D C
Sbjct: 1164 ----KMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEE-RNCTDIDECRISP-DLCGRGQC 1217
Query: 452 INLPGSFQCRCRDGWRGD---GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
+N PG F+C+C +G+ C D+DEC + C C NT+GS+RC C G++
Sbjct: 1218 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCR-GGVCHNTEGSYRCECPPGHQ 1276
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ +C+DI+EC LC NG C N G Y+C C+ G+ D C+
Sbjct: 1277 LSPN-------ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCV 1327
Score = 190 bits (463), Expect = 1e-47
Identities = 107/306 (34%), Positives = 138/306 (45%), Gaps = 30/306 (9%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC +C +G C N G + C C GY D +CVD+NEC C + C
Sbjct: 2533 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC-NFICK 2591
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NTEGS+ C C GY + + C D+DECA C+ CVNT G F C+C G
Sbjct: 2592 NTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ-FLCVNTIGGFTCKCPPG--FTQ 2648
Query: 238 DRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
SC D +EC+ +C S G C+N G++ C C G++ S R
Sbjct: 2649 HHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGS-SCEDVDECEGNHR 2707
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
CQH C N G Y C+C +G+ C D +EC A CGG C NT+GSY C C
Sbjct: 2708 CQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECL-SAHICGGASCHNTLGSYKCMCPA 2766
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G CQDI+EC Q P C G C NT G ++C
Sbjct: 2767 GFQYEQFSG--GCQDINECG------------------SAQAP--CSYG-CSNTEGGYLC 2803
Query: 417 QCPDGY 422
CP GY
Sbjct: 2804 GCPPGY 2809
Score = 174 bits (423), Expect = 8e-43
Identities = 124/389 (31%), Positives = 172/389 (44%), Gaps = 61/389 (15%)
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
D C LC+ GRC+ T GS+RCEC G +L R C D+DEC C+ G C N
Sbjct: 582 DYCQLVRYLCQNGRCIPTPGSYRCECNKGFQL-DLRGECIDVDECE--KNPCAGGECINN 638
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADG 322
G+Y C C GY + ++ C + C+NT GS+HC C G+H+ DG
Sbjct: 639 QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDG 698
Query: 323 RSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTI 382
++C D+DEC+ C G C N GS+ C C G ++ G C+DI+EC
Sbjct: 699 KNCEDMDECS-IRNMCLNGMCINEDGSFKCICKPGFQLASDGR--YCKDINEC------- 748
Query: 383 IMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGT 442
+ P +C G C NT GS+ C+C G +V + G C D T
Sbjct: 749 --------------ETPGICMNGRCVNTDGSYRCECFPGLAVGLD-GRVCVDTH--MRST 791
Query: 443 C-DCHPAADCIN-LPGSF---QCRCRDGWRGDGATCEDVD-------ECLTNNGGCHPRA 490
C + CI L G+ +C C G C+ + L ++G P
Sbjct: 792 CYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG---PGM 848
Query: 491 TCANTDGSFRCLCDTGYKGDGY--GLR-TVCCV-----------YSCVDIDECANDPTLC 536
T A +D + C D +G LR T C+ +CVDI+EC + LC
Sbjct: 849 TSAGSDIN-ECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLC 907
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+NG C NTPG + C C GF D ++C
Sbjct: 908 DNGQCRNTPGSFVCTCPKGFIYKPDLKTC 936
Score = 165 bits (400), Expect = 5e-40
Identities = 89/242 (36%), Positives = 113/242 (46%), Gaps = 8/242 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++NEC P C C+N G + C C GY +C D++EC C C
Sbjct: 2574 VDLNECNQAPKPCNF-ICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNC-QFLC 2631
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G FTC C PG+ S C+D +EC + LC G C NT GSF CEC G L
Sbjct: 2632 VNTIGGFTCKCPPGFTQHHTS--CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSL 2689
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
SC+D+DEC + C +G C+N +G Y+C C +GY Q +
Sbjct: 2690 DQTGSSCEDVDECE-GNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHI 2747
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
SC NT GSY C C G+ C+DI+EC PC G C NT G Y C C
Sbjct: 2748 CGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCP 2806
Query: 356 DG 357
G
Sbjct: 2807 PG 2808
Score = 146 bits (353), Expect = 2e-34
Identities = 76/227 (33%), Positives = 105/227 (46%), Gaps = 9/227 (3%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHT-CVDVNECEIVDGVCGD-GD 175
+++ECA C C N +GGFTC C PG+ +++HT C+D NEC +CG G
Sbjct: 2616 DLDECATKQHNCQF-LCVNTIGGFTCKCPPGF---TQHHTSCIDNNECTSDINLCGSKGI 2671
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C NT GSFTC C+ G+ D C D+DEC N C+ G C N G +RC C G
Sbjct: 2672 CQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQGYLQ 2729
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
C D +EC +++ IC +C N +G+Y+C+C G+
Sbjct: 2730 HYQWNQCVDENEC-LSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQA 2788
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ 342
C + C NT G Y C C G+ G + G P G+
Sbjct: 2789 PCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGE 2835
Score = 132 bits (318), Expect = 4e-30
Identities = 98/341 (28%), Positives = 138/341 (40%), Gaps = 29/341 (8%)
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ-H 299
+C+D+DEC G+C G C N +G+++C C G+ + V C+
Sbjct: 374 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 433
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN----TVGSYTCTCT 355
C NT SY C C G++ DG C D+ G+C N ++ C C
Sbjct: 434 ECTNTVSSYFCKCPPGFYTSPDGTRCIDV-RPGYCYTALTNGRCSNQLPQSITKMQCCCD 492
Query: 356 DGLV--PSAAGAKPTC-----QDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCH 408
G P A C +D ++ + +I + + P P L
Sbjct: 493 AGRCWSPGVTVAPEMCPIRATEDFNKLCS-VPMVIPGRPEYPPPPLGPIPPVLPVPPGFP 551
Query: 409 NTIGSFVCQCPDGY---SVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
V + P Y S +P + D C+L C CI PGS++C C G
Sbjct: 552 PGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGR-CIPTPGSYRCECNKG 610
Query: 466 WRGD-GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
++ D C DVDEC N C C N GS+ C C GY+ RT C
Sbjct: 611 FQLDLRGECIDVDECEKN--PC-AGGECINNQGSYTCQCRAGYQST--LTRT-----ECR 660
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DIDEC + +C NG C NT G + C C+ GF DG++C
Sbjct: 661 DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNC 701
Score = 129 bits (311), Expect = 3e-29
Identities = 83/231 (35%), Positives = 100/231 (43%), Gaps = 39/231 (16%)
Query: 338 CGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
C G+C T GSY C C G G C D+DEC +P
Sbjct: 591 CQNGRCIPTPGSYRCECNKGFQLDLRGE---CIDVDECEK-----------------NP- 629
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
C G C N GS+ CQC GY + C D DEC C+ CIN GS
Sbjct: 630 ----CAGGECINNQGSYTCQCRAGYQSTLTR-TECRDIDECLQNGRICNNGR-CINTDGS 683
Query: 458 FQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
F C C G+ DG CED+DEC N + C N DGSF+C+C G++ G
Sbjct: 684 FHCVCNAGFHVTRDGKNCEDMDECSIRNMCLN--GMCINEDGSFKCICKPGFQLASDGRY 741
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DI+EC P +C NG C NT G Y C+C G DGR C+
Sbjct: 742 -------CKDINECET-PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV 784
Score = 113 bits (273), Expect = 1e-24
Identities = 52/134 (38%), Positives = 74/134 (55%), Gaps = 5/134 (3%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
C G+ + + C DV+EC+ + G+C G+C NT GSF C C G+K ++ S+ C DID
Sbjct: 362 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 421
Query: 205 ECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDI--DEC--SITSGICSNGAC 260
EC+ +C GG C NT S+ C+C G +PD C D+ C ++T+G CSN
Sbjct: 422 ECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSN-QL 480
Query: 261 ENQMGTYQCVCDEG 274
+ QC CD G
Sbjct: 481 PQSITKMQCCCDAG 494
Score = 96.3 bits (229), Expect = 3e-19
Identities = 86/309 (27%), Positives = 119/309 (38%), Gaps = 45/309 (14%)
Query: 136 NLLGG-FTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYK 192
N+ G + C PG++ + C V + DG C + C G C G +
Sbjct: 188 NVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSC--GSR 245
Query: 193 ADDFSKI-CVDIDECADNDALCRGGRCVNTAGSFRCECG---HGMELAPDRLSCKDIDEC 248
+ I C++ C+D+ LC+ G G CE G G +AP+R C
Sbjct: 246 SIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNR--------C 297
Query: 249 SITSGICSNGACENQMGTYQC--VCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHSCVNTP 305
+ T G + CE T C V Q + R H C P
Sbjct: 298 ACTYGF-TGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCP 356
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGA 365
H CR G+ +C+D+DEC C GG C NTVGS+ C C G +
Sbjct: 357 AQPH-PCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQ 415
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVK 425
K C+DIDEC+ IP +C G C NT+ S+ C+CP G+
Sbjct: 416 K--CEDIDECS--------------------TIPGICEGGECTNTVSSYFCKCPPGFYTS 453
Query: 426 PEQGPACTD 434
P+ G C D
Sbjct: 454 PD-GTRCID 461
Score = 94.7 bits (225), Expect = 8e-19
Identities = 85/275 (30%), Positives = 107/275 (38%), Gaps = 35/275 (12%)
Query: 297 CQHSCVNTPGSYH--CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+HSC + S CTC G + G R I C R GG C + C C
Sbjct: 216 CRHSCGDGFCSRPNMCTCPSGQIAPSCGS--RSIQHC--NIRCMNGGSCSDD----HCLC 267
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + + G +P C+ C + + PQ G C I +
Sbjct: 268 QKGYIGTHCG-QPVCES--GCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQ 324
Query: 415 VCQCPDGYSVKPEQGPACTDDDECE-LGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT- 472
+CQ G CT C +G HP C P CR G+ + T
Sbjct: 325 MCQ-------GQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHP----CRRGFIPNIRTG 373
Query: 473 -CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
C+DVDEC G C C NT GSF C C G+K L V C DIDEC+
Sbjct: 374 ACQDVDECQAIPGLCQG-GNCINTVGSFECKCPAGHK-----LNEVS--QKCEDIDECST 425
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P +CE G C+NT Y C C GF + DG C+
Sbjct: 426 IPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCI 460
Score = 91.5 bits (217), Expect = 7e-18
Identities = 39/103 (37%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC A PGLC G C N +G F C C G++ + + C D++EC + G+C G+C
Sbjct: 377 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 436
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVN 220
NT S+ C C PG+ C+D+ AL GRC N
Sbjct: 437 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTAL-TNGRCSN 478
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
GG+CS P + + CCC+ G+ WG+ CE CP + +A++ +C
Sbjct: 2198 GGKCSSPKSRNHSKQECCCALKGEGWGDP-CELCPTEPDEAFRQIC 2242
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C+ P+ CCCS +G AWG + CE CP + T Y+ LC
Sbjct: 1098 CTLPIAGRHRMDACCCS-VGAAWGTEECEECPMRNTPEYEELC 1139
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 1 MTGGRCSGPLPTDVLRAVCCCSALGKAWG---NQRCEPCPKKGTDAYQNLCIAVGTLLP 56
+T GRCS LP + + CCC A G+ W E CP + T+ + LC +V ++P
Sbjct: 471 LTNGRCSNQLPQSITKMQCCCDA-GRCWSPGVTVAPEMCPIRATEDFNKLC-SVPMVIP 527
Score = 43.6 bits (98), Expect = 0.002
Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
G+C PL V ++ CCC++ A+G + C+PCP + + YQ LC
Sbjct: 799 GQCIKPLFGAVTKSECCCASTEYAFG-EPCQPCPAQNSAEYQALC 842
Score = 39.1 bits (87), Expect = 0.041
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V ++ CCC G+ WG CE CP +GT A++ LC
Sbjct: 2489 VTKSECCCDG-GRGWG-PHCEICPFQGTVAFKKLC 2521
Score = 35.5 bits (78), Expect = 0.51
Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCP 37
C G L V CC+ +G+AWG+ CE CP
Sbjct: 326 CQGQLSGIVCTKTLCCATVGRAWGHP-CEMCP 356
>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
Length = 2871
Score = 429 bits (1056), Expect = e-119
Identities = 196/449 (43%), Positives = 253/449 (56%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NEC P LC HG+CRN +G F C C G+ DS+ C D++EC I +CG G C
Sbjct: 1028 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT G F C C GY++ K C+DIDEC + LCRGG C NT GS+RCEC G +L+
Sbjct: 1088 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS 1147
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
P+ +C DI+EC +++ +C NG C N +G YQC C+ GY + +
Sbjct: 1148 PNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGG 1207
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C+ C N+ GSY C+C+ G+ L D RSC DIDEC C GGQC N G Y C C D
Sbjct: 1208 CETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYD 1267
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A+ TC D++EC DL P +C +G+C NT GSF+C
Sbjct: 1268 GFM--ASEDMKTCVDVNEC-DL-------------------NPNICLSGTCENTKGSFIC 1305
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GYS K + CTD +ECE+G +C A C N GSF+C C GW GDG C D+
Sbjct: 1306 HCDMGYSGKKGK-TGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDL 1364
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC C A C NT GS+RCLC GY GDG ++C D+DEC+ + LC
Sbjct: 1365 DECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDG---------FTCTDLDECSENLNLC 1415
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
NG C N PGGY C+CD+GF +ADG++C
Sbjct: 1416 GNGQCLNAPGGYRCECDMGFVPSADGKAC 1444
Score = 301 bits (740), Expect = 3e-81
Identities = 165/445 (37%), Positives = 219/445 (49%), Gaps = 44/445 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+++EC P LC G C N G + C+C PG++ C+D+NECE+ +C +G C
Sbjct: 1112 MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRC 1171
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G + C C PGY + CVDIDEC+ + C C N+ GS+ C C G L
Sbjct: 1172 VNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCE-TFCTNSEGSYECSCQPGFALM 1230
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXX 295
PD+ SC DIDEC IC G C N G Y+C+C +G+ A +K+
Sbjct: 1231 PDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNI 1290
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTC 354
+C NT GS+ C C G+ + C DI+EC GA CG C NT GS+ C+C
Sbjct: 1291 CLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSC 1350
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGS 413
+ G + G K C D+DEC++ T +C C NT+GS
Sbjct: 1351 SPGWI--GDGIK--CTDLDECSN--GT------------------HMCSQHADCKNTMGS 1386
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGA 471
+ C C +GY+ G CTD DEC C C+N PG ++C C G+ DG
Sbjct: 1387 YRCLCKEGYT---GDGFTCTDLDECSENLNLC-GNGQCLNAPGGYRCECDMGFVPSADGK 1442
Query: 472 TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
CED+DEC N TC N G FRC C+ GY+ D G +C D++EC
Sbjct: 1443 ACEDIDECSLPN--ICVFGTCHNLPGLFRCECEIGYELDRSG-------GNCTDVNECL- 1492
Query: 532 DPTLCENGHCSNTPGGYECDCDVGF 556
DPT C +G+C NTPG Y CDC F
Sbjct: 1493 DPTTCISGNCVNTPGSYICDCPPDF 1517
Score = 291 bits (714), Expect = 4e-78
Identities = 172/506 (33%), Positives = 238/506 (47%), Gaps = 70/506 (13%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++NEC LC +GRC NL+G + C C PGY CVD++EC I++G C + C
Sbjct: 1154 IDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGC-ETFC 1212
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N+EGS+ C C+PG+ + C DIDEC DN +C GG+C N G +RC C G +
Sbjct: 1213 TNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMAS 1272
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
D +C D++EC + IC +G CEN G++ C CD GY+ K+
Sbjct: 1273 EDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHN 1332
Query: 297 C-QHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCT 353
C +H+ C NT GS+ C+C GW DG C D+DEC+ G C C+NT+GSY C
Sbjct: 1333 CGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL 1390
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTI-------------------IMMSVD-ELQKS 393
C +G G TC D+DEC++ ++ + S D + +
Sbjct: 1391 CKEGYT----GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACED 1446
Query: 394 VDP-QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCI 452
+D +P +C G+CHN G F C+C GY + G CTD +EC L C + +C+
Sbjct: 1447 IDECSLPNICVFGTCHNLPGLFRCECEIGYELD-RSGGNCTDVNEC-LDPTTCI-SGNCV 1503
Query: 453 NLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCH----PRA-----TCANTDG----SF 499
N PGS+ C C + + VD T +G C+ PR C+N G
Sbjct: 1504 NTPGSYICDCPPDFELNPTRVGCVD---TRSGNCYLDIRPRGDNGDTACSNEIGVGVSKA 1560
Query: 500 RCLCDTG-----------------YK---GDGYGLRTVCCVYSCVDIDECANDPTLCENG 539
C C G YK G G R DIDEC P LC+ G
Sbjct: 1561 SCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGG 1620
Query: 540 HCSNTPGGYECDCDVGFTRAADGRSC 565
C NT G ++C C G+ D R C
Sbjct: 1621 KCINTFGSFQCRCPTGYYLNEDTRVC 1646
Score = 255 bits (624), Expect = 4e-67
Identities = 184/548 (33%), Positives = 232/548 (42%), Gaps = 82/548 (14%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWDRPID 65
CS + V +A CCCS LGKAWG CE CP T Y+ LC G PN PI
Sbjct: 1549 CSNEIGVGVSKASCCCS-LGKAWGTP-CEMCPAVNTSEYKILCPG-GEGFRPN----PIT 1601
Query: 66 GNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNECAAF 125
+ DI DE + G G +VNEC
Sbjct: 1602 VILEDI------DECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET- 1654
Query: 126 PGLCGHGRCRNLL---------------GGFTCD------CFPGYEKDS----------- 153
PG+CG G C N + GG C C+ Y D+
Sbjct: 1655 PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNM 1714
Query: 154 -KNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC---RPGYKADDFSKICVDIDECADN 209
K C N + C +T+ F C RPG+ D ++ + VDIDEC +
Sbjct: 1715 TKKMCCCSYNIGRAWNKPCEQCPIPSTD-EFATLCGSQRPGFVIDIYTGLPVDIDECREI 1773
Query: 210 DALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQ 268
+C G C+N GSFRCEC G L C+DIDEC +C N C N G+Y+
Sbjct: 1774 PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECINTAGSYR 1832
Query: 269 CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH-SCVNTPGSYHCTCREGWHLRADGRSCRD 327
C C GY + T C H C++T GS++C C G+ D C D
Sbjct: 1833 CDCKPGY-RFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLD 1891
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
I+EC A CG G CRNT+GS+ C C G + S C D+DECA
Sbjct: 1892 INECERDA--CGNGTCRNTIGSFNCRCNHGFILS---HNNDCIDVDECAS---------- 1936
Query: 388 DELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
LC G C NT+GSF CQC +GY V P+ G C D +EC L C P
Sbjct: 1937 ---------GNGNLCRNGQCINTVGSFQCQCNEGYEVAPD-GRTCVDINECLLEPRKCAP 1986
Query: 448 AADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
C NL GS++C C G+ CED+DEC+ C TC+NT+GSF+CLC G+
Sbjct: 1987 GT-CQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEIC-ALGTCSNTEGSFKCLCPEGF 2044
Query: 508 KGDGYGLR 515
G R
Sbjct: 2045 SLSSSGRR 2052
Score = 254 bits (623), Expect = 5e-67
Identities = 152/452 (33%), Positives = 218/452 (48%), Gaps = 53/452 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC PG+C +G C N++G F C+C G+ + K C D++EC+ + +C
Sbjct: 1765 VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC 1824
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS+ C C+PGY+ + C D +EC + +C G+C++T GSF C C G +
Sbjct: 1825 INTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTN 1883
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
D+ C DI+EC + C NG C N +G++ C C+ G+ S
Sbjct: 1884 DDQTMCLDINECERDA--CGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNL 1941
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
C++ C+NT GS+ C C EG+ + DGR+C DI+EC R C G C+N GSY C C
Sbjct: 1942 CRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICP 2001
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G S K C+DIDEC V+E PE+C G+C NT GSF
Sbjct: 2002 PGY--SLQNEK--CEDIDEC-----------VEE---------PEICALGTCSNTEGSFK 2037
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCED 475
C CP+G+S+ G C D + C + P S R+ + + C
Sbjct: 2038 CLCPEGFSLS-SSGRRCQD---LRMSYCYAKFEGGKCSSPKS-----RNHSKQE-CCC-- 2085
Query: 476 VDECLTNNGGCHPRATC-ANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
L G P C D +FR +C G G G S VD+DEC +P
Sbjct: 2086 ---ALKGEGWGDPCELCPTEPDEAFRQICPYG-SGIIVGPDD-----SAVDMDEC-KEPD 2135
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C++G C NT G Y C+C G+T A G C+
Sbjct: 2136 VCKHGQCINTDGSYRCECPFGYTLA--GNECV 2165
Score = 250 bits (612), Expect = 1e-65
Identities = 156/466 (33%), Positives = 209/466 (44%), Gaps = 73/466 (15%)
Query: 134 CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKA 193
C+NL+G + C C PGY++ CVD NEC+ G+C +G C NT GS+TC C G+ A
Sbjct: 2265 CKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTA 2324
Query: 194 DDFSKICVDIDE--CADN--DALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCK----- 243
C+D E C +C+ G N C C G P C
Sbjct: 2325 SPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTV 2384
Query: 244 -----------------DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
DIDEC + +C NG C N G+Y C+C GY +
Sbjct: 2385 AFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVD 2444
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT 346
C C NT GSY C+C +G+ L+ DGRSC+D+DECA C C NT
Sbjct: 2445 LNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF-LCVNT 2503
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-G 405
+G +TC C G +C D +EC I+ LCG+ G
Sbjct: 2504 IGGFTCKCPPGFTQHHT----SCIDNNECTSDIN--------------------LCGSKG 2539
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C NT GSF C+C G+S+ + G +C D DECE G C C N+ G ++C C G
Sbjct: 2540 ICQNTPGSFTCECQRGFSLD-QTGSSCEDVDECE-GNHRCQHG--CQNIIGGYRCSCPQG 2595
Query: 466 W--RGDGATCEDVDECLTNN--GGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
+ C D +ECL+ + GG A+C NT GS++C+C G++ + +
Sbjct: 2596 YLQHYQWNQCVDENECLSAHICGG----ASCHNTLGSYKCMCPAGFQYEQFS-------G 2644
Query: 522 SCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
C DI+EC + C G CSNT GGY C C G+ R G G
Sbjct: 2645 GCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGYFRIGQGHCVSG 2689
Score = 246 bits (601), Expect = 2e-64
Identities = 157/466 (33%), Positives = 210/466 (45%), Gaps = 43/466 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC P +C HG+C N G + C+C GY + CVD +EC V CG+G C
Sbjct: 2126 VDMDECKE-PDVCKHGQCINTDGSYRCECPFGY--TLAGNECVDTDECS-VGNPCGNGTC 2181
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G F C C G++ C DI+ECA N LC RCVNT GS+ C+C G L
Sbjct: 2182 KNVIGGFECTCEEGFEPGPM-MTCEDINECAQNPLLC-AFRCVNTYGSYECKCPVGYVLR 2239
Query: 237 PDRLSCKDIDECSITSGICSNG--ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
DR CKD DEC C+ C+N +GTY C+C GY +
Sbjct: 2240 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2299
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDE--CAGGA--RPCG-GGQCRNTVG 348
C++ C+NT GSY C C +G+ + C D E C C G RN V
Sbjct: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT 2359
Query: 349 SYTCTCTDGLVPSAAGAKPTCQDID-ECADLISTIIMMSVDELQKSVD----PQIPELCG 403
C C G G P C+ + + + D I ++C
Sbjct: 2360 KSECCCDGG-----RGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCR 2414
Query: 404 AGSCHNTIGSFVCQCPDGYSVKPE-QGPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
G C N GS+ C C GY+ P+ G +C D +EC C+ C N GS+QC C
Sbjct: 2415 NGECVNDRGSYHCICKTGYT--PDITGTSCVDLNECNQAPKPCN--FICKNTEGSYQCSC 2470
Query: 463 RDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ + DG +C+D+DEC T C + C NT G F C C G+
Sbjct: 2471 PKGYILQEDGRSCKDLDECATKQHNC--QFLCVNTIGGFTCKCPPGFTQHH--------- 2519
Query: 521 YSCVDIDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
SC+D +EC +D LC G C NTPG + C+C GF+ G SC
Sbjct: 2520 TSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSC 2565
Score = 245 bits (600), Expect = 3e-64
Identities = 155/471 (32%), Positives = 212/471 (45%), Gaps = 42/471 (8%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC P +C G+C N+ G + C C+ G+ TCVDVNEC++ +C G C
Sbjct: 1238 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCE 1297
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC GY C DI+EC C + C NTAGSF+C C G
Sbjct: 1298 NTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW--I 1355
Query: 237 PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D + C D+DECS + +CS A C+N MG+Y+C+C EGY
Sbjct: 1356 GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTC--TDLDECSENLN 1413
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C + C+N PG Y C C G+ ADG++C DIDEC+ C G C N G + C C
Sbjct: 1414 LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNLPGLFRCEC 1472
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPEL--------C---G 403
G +G C D++EC D + I V+ + P+ C
Sbjct: 1473 EIGYELDRSGGN--CTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTR 1530
Query: 404 AGSCHNTI------GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
+G+C+ I G C G V + C + C+ PA +
Sbjct: 1531 SGNCYLDIRPRGDNGDTACSNEIGVGVS--KASCCCSLGKAWGTPCEMCPAVNTSEY--K 1586
Query: 458 FQCRCRDGWRGDGATC--EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
C +G+R + T ED+DEC G C C NT GSF+C C TGY L
Sbjct: 1587 ILCPGGEGFRPNPITVILEDIDECQELPGLCQG-GKCINTFGSFQCRCPTGYY-----LN 1640
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
V C D++EC P +C G C NT G Y C C + + G +C+
Sbjct: 1641 EDTRV--CDDVNECET-PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCM 1688
Score = 243 bits (595), Expect = 1e-63
Identities = 139/394 (35%), Positives = 190/394 (48%), Gaps = 22/394 (5%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C LC +GRC G + C+C G++ D + C+DV+ECE C G+C N +G
Sbjct: 453 CQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGE-CIDVDECE--KNPCAGGECINNQG 509
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
S+TC CR GY++ C DIDEC N +C GRC+NT GSF C C G + D +
Sbjct: 510 SYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 569
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C+D+DECSI + +C NG C N+ G+++C+C G+ ++ + C
Sbjct: 570 CEDMDECSIRN-MCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRC 628
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDI---DECAGGARPCGGGQC-RNTVGSYT---CTC 354
VNT GSY C C G + DGR C D C GG + GQC + G+ T C C
Sbjct: 629 VNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYK---RGQCIKPLFGAVTKSECCC 685
Query: 355 TDGLVPSAAGAKP-TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
+P Q+ E L S+ M+ + P++C G C N G+
Sbjct: 686 ASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGT 745
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG--WRGDGA 471
+ C C GY V G C D +EC L + C C N PGSF C C G ++ D
Sbjct: 746 YKCICNSGYEV-DSTGKNCVDINECVLNSLLC-DNGQCRNTPGSFVCTCPKGFIYKPDLK 803
Query: 472 TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
TCED+DEC + C C N+ GSF C C +
Sbjct: 804 TCEDIDEC--ESSPC-INGVCKNSPGSFICECSS 834
Score = 240 bits (587), Expect = 1e-62
Identities = 155/461 (33%), Positives = 207/461 (44%), Gaps = 68/461 (14%)
Query: 117 MEVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA+ G LC +G+C N +G F C C GYE TCVD+NEC + C G
Sbjct: 1929 IDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGT 1988
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N +GS+ C C PGY + + C DIDEC + +C G C NT GSF+C C G L
Sbjct: 1989 CQNLDGSYRCICPPGYSLQN--EKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSL 2046
Query: 236 APDRLSCKDI--DEC--SITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ C+D+ C G CS+ N +C C +K
Sbjct: 2047 SSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNH-SKQECCC-------ALKGEGWGDP--- 2095
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWHLRAD-GRSCRDIDECAGGARPCGGGQCRNTVGSY 350
C+ ++ C G + S D+DEC C GQC NT GSY
Sbjct: 2096 -----CELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKE-PDVCKHGQCINTDGSY 2149
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNT 410
C C G + AG + C D DEC+ + CG G+C N
Sbjct: 2150 RCECPFGY--TLAGNE--CVDTDECS---------------------VGNPCGNGTCKNV 2184
Query: 411 IGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RG 468
IG F C C +G+ P C D +EC C A C+N GS++C+C G+ R
Sbjct: 2185 IGGFECTCEEGFEPGPMM--TCEDINECAQNPLLC--AFRCVNTYGSYECKCPVGYVLRE 2240
Query: 469 DGATCEDVDECLTNNGGC-HPRATCANTDGSFRCLCDTGY--KGDGYGLRTVCCVYSCVD 525
D C+D DEC C + C N G++ C+C GY + DG G CVD
Sbjct: 2241 DRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEG---------CVD 2291
Query: 526 IDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+EC P +CENG C NT G Y C+C+ GFT + + CL
Sbjct: 2292 ENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 2332
Score = 239 bits (584), Expect = 2e-62
Identities = 166/508 (32%), Positives = 224/508 (44%), Gaps = 94/508 (18%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDV-----------NECEI 166
+++EC + P C +G C+N G F C+C D C++ CEI
Sbjct: 807 DIDECESSP--CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEI 864
Query: 167 -VDGVCGDGDCHNTEGSF------TCH----CRPGYKADDFSKICVDIDECADNDALCRG 215
++G C ++ G+ C C GY ++ C DIDEC +C+
Sbjct: 865 NINGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQ-CEDIDECEVFPGVCKN 923
Query: 216 GRCVNTAGSFRCECGHGMELAPDRLSCKDI-----------DECSITSG--------ICS 256
G CVNT GSF+C+C GM L C DI +EC++ CS
Sbjct: 924 GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCS 983
Query: 257 NGA------CEN----QMGTYQCVCDEG--YAQSTV---KSHXXXXXXXXXXXXRCQHS- 300
GA CE Y+ +C G +A + K C H
Sbjct: 984 VGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGK 1043
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP 360
C NT GS+ C C G+ L ++ R+C DIDEC CG GQC NT G + C C +G
Sbjct: 1044 CRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYES 1103
Query: 361 SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD 420
K C DIDEC Q+ P LC G CHNT GS+ C+CP
Sbjct: 1104 GFMMMK-NCMDIDEC---------------QRD-----PLLCRGGVCHNTEGSYRCECPP 1142
Query: 421 GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDE 478
G+ + P AC D +ECEL C P C+NL G +QC C G+ D C D+DE
Sbjct: 1143 GHQLSPNIS-ACIDINECELSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1200
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN 538
C NGGC C N++GS+ C C G+ + SC DIDEC ++P +C+
Sbjct: 1201 CSIMNGGCE--TFCTNSEGSYECSCQPGFA-------LMPDQRSCTDIDECEDNPNICDG 1251
Query: 539 GHCSNTPGGYECDCDVGFTRAADGRSCL 566
G C+N PG Y C C GF + D ++C+
Sbjct: 1252 GQCTNIPGEYRCLCYDGFMASEDMKTCV 1279
Score = 239 bits (584), Expect = 2e-62
Identities = 153/480 (31%), Positives = 207/480 (43%), Gaps = 68/480 (14%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++ +EC+ CG+G C+N++GGF C C G+E TC D+NEC +C C
Sbjct: 2165 VDTDECSV-GNPCGNGTCKNVIGGFECTCEEGFEPGPMM-TCEDINECAQNPLLCAFR-C 2221
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC--RGGRCVNTAGSFRCECGHGME 234
NT GS+ C C GY + ++C D DEC + C + C N G++ C CG G +
Sbjct: 2222 VNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQ 2281
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
PD C D +EC GIC NG C N G+Y C C++G+ S +
Sbjct: 2282 RRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFT 2341
Query: 295 XRCQHSCV------NTPGSYHCTCR--EGW--------------------HLRADGRSCR 326
Q+ C N C C GW H R +
Sbjct: 2342 EVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA 2401
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
DIDEC C G+C N GSY C C G P G +C D++EC
Sbjct: 2402 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGT--SCVDLNECN---------- 2449
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCH 446
Q P+ C C NT GS+ C CP GY ++ E G +C D DEC +C
Sbjct: 2450 ----------QAPKPCNF-ICKNTEGSYQCSCPKGYILQ-EDGRSCKDLDECATKQHNCQ 2497
Query: 447 PAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
C+N G F C+C G+ +C D +EC ++ C + C NT GSF C C G
Sbjct: 2498 FL--CVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRG 2555
Query: 507 YKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ D G SC D+DEC + C++G C N GGY C C G+ + C+
Sbjct: 2556 FSLDQTG-------SSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQGYLQHYQWNQCV 2606
Score = 223 bits (546), Expect = 1e-57
Identities = 155/464 (33%), Positives = 202/464 (43%), Gaps = 47/464 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C C GYE DS CVD+NEC + +C +G C
Sbjct: 723 DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCR 782
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT GSF C C G+ K C DIDEC + C G C N+ GSF CEC L P
Sbjct: 783 NTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSSESTLDP 840
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
+ C G C + + C+ +T+KS C
Sbjct: 841 TKTIC-----IETIKGTCWQTVIDGR-------CEININGATLKSQ-CCSSLGAAWGSPC 887
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
C P C +G+ R G C DIDEC C G C NT GS+ C C G
Sbjct: 888 T-LCQVDP-----ICGKGYS-RIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSG 940
Query: 358 LVPSAAGAKPTCQDI--DEC----ADLISTIIMMS---VDELQKSVDPQI-PELCGAGSC 407
+ A G C DI + C D T+ + +D SV E C
Sbjct: 941 MTLDATGR--ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPM 998
Query: 408 HNTIG-SFVCQCPDGYSVK--PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
NT +C G++ K P D +EC++ C C N GSF+CRC
Sbjct: 999 RNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLC-THGKCRNTIGSFKCRCDS 1057
Query: 465 GWRGDG--ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ D C D+DEC + C R C NT G F C CD GY+ G+ + + +
Sbjct: 1058 GFALDSEERNCTDIDECRISPDLC-GRGQCVNTPGDFECKCDEGYE-SGFMM-----MKN 1110
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C+DIDEC DP LC G C NT G Y C+C G + + +C+
Sbjct: 1111 CMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACI 1154
Score = 215 bits (525), Expect = 3e-55
Identities = 153/467 (32%), Positives = 198/467 (42%), Gaps = 63/467 (13%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC +C +GRC N G F C C G+ C D++EC I +C +G C
Sbjct: 530 DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI-RNMCLNGMCI 588
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N +GSF C C+PG++ + C DI+EC + +C GRCVNT GS+RCEC G+ +
Sbjct: 589 NEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRCECFPGLAVGL 647
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
D C D S G G QC+ + + KS C
Sbjct: 648 DGRVCVDTHMRSTCYGGYKRG---------QCI--KPLFGAVTKSECCCASTEYAFGEPC 696
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
Q Y C G + + G DI+ECA C G C N G+Y C C G
Sbjct: 697 QPCPAQNSAEYQALCSSGPGMTSAG---SDINECALDPDICPNGICENLRGTYKCICNSG 753
Query: 358 LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQ 417
+ G C DI+EC ++ S+ LC G C NT GSFVC
Sbjct: 754 YEVDSTG--KNCVDINEC-------VLNSL-------------LCDNGQCRNTPGSFVCT 791
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD-------- 469
CP G+ KP+ C D DECE C C N PGSF C C D
Sbjct: 792 CPKGFIYKPDL-KTCEDIDECESSPC---INGVCKNSPGSFICECSSESTLDPTKTICIE 847
Query: 470 --GATCED--VD-ECLTNNGGCHPRATCANTDGS---FRC-LCDTG-YKGDGYGLRTVCC 519
TC +D C N G ++ C ++ G+ C LC G GY
Sbjct: 848 TIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGT- 906
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DIDEC P +C+NG C NT G ++C C G T A GR CL
Sbjct: 907 --QCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICL 951
Score = 211 bits (516), Expect = 4e-54
Identities = 132/398 (33%), Positives = 177/398 (44%), Gaps = 36/398 (9%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GD 175
++NEC CG H C N G F C C PG+ D C D++EC +C D
Sbjct: 1322 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIK--CTDLDECSNGTHMCSQHAD 1379
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C NT GS+ C C+ GY D F+ C D+DEC++N LC G+C+N G +RCEC G
Sbjct: 1380 CKNTMGSYRCLCKEGYTGDGFT--CTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVP 1437
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C+DIDECS+ + IC G C N G ++C C+ GY +
Sbjct: 1438 SADGKACEDIDECSLPN-ICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTT 1496
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDI--DECAGGARPCGGG---QCRNTVG-- 348
+CVNTPGSY C C + L C D C RP G C N +G
Sbjct: 1497 CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVG 1556
Query: 349 --SYTCTCTDG--------LVP--SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDP 396
+C C+ G + P + + K C + T+I+ +DE Q
Sbjct: 1557 VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQ----- 1611
Query: 397 QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPG 456
++P LC G C NT GSF C+CP GY + E C D +ECE C P C N G
Sbjct: 1612 ELPGLCQGGKCINTFGSFQCRCPTGYYLN-EDTRVCDDVNECETPGI-CGPGT-CYNTVG 1668
Query: 457 SFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATC 492
++ C C + G C D+ L TC
Sbjct: 1669 NYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
Score = 203 bits (496), Expect = 1e-51
Identities = 140/422 (33%), Positives = 194/422 (45%), Gaps = 48/422 (11%)
Query: 157 TCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGG 216
+ VD++EC+ D VC G C NT+GS+ C C GY CVD DEC+ + C G
Sbjct: 2124 SAVDMDECKEPD-VCKHGQCINTDGSYRCECPFGYTLA--GNECVDTDECSVGNP-CGNG 2179
Query: 217 RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYA 276
C N G F C C G E P ++C+DI+EC+ +C+ C N G+Y+C C GY
Sbjct: 2180 TCKNVIGGFECTCEEGFEPGP-MMTCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYV 2237
Query: 277 QSTVKSHXXXXXXXXXXXXRC---QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAG 333
+ C Q C N G+Y C C G+ R DG C D +EC
Sbjct: 2238 LREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQT 2297
Query: 334 GARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKS 393
C G+C NT GSYTC C DG +A+ + C +D T ++ ++ ++ S
Sbjct: 2298 KPGICENGRCLNTRGSYTCECNDGF--TASPNQDEC--LDNREGYCFTEVLQNMCQIGSS 2353
Query: 394 -VDPQIPELC----GAG---SC-----HNTIGSFVCQCPDGYSVKPEQGPACTDDDECEL 440
+P C G G C T+ +F CP G D DEC++
Sbjct: 2354 NRNPVTKSECCCDGGRGWGPHCEICPFQGTV-AFKKLCPHGRGFMTNG----ADIDECKV 2408
Query: 441 GTCDCHPAADCINLPGSFQCRCRDGWRGD--GATCEDVDECLTNNGGCHPRATCANTDGS 498
C +C+N GS+ C C+ G+ D G +C D++EC C+ C NT+GS
Sbjct: 2409 IHDVCR-NGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN--FICKNTEGS 2465
Query: 499 FRCLCDTGY--KGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
++C C GY + DG SC D+DECA C+ C NT GG+ C C GF
Sbjct: 2466 YQCSCPKGYILQEDG---------RSCKDLDECATKQHNCQ-FLCVNTIGGFTCKCPPGF 2515
Query: 557 TR 558
T+
Sbjct: 2516 TQ 2517
Score = 201 bits (490), Expect = 6e-51
Identities = 144/478 (30%), Positives = 197/478 (41%), Gaps = 73/478 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++NEC LC +G+CRN G F C C G+ TC D++ECE C +G C
Sbjct: 764 VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECE--SSPCINGVC 821
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD----------ID-ECADN-DALCRGGRCVNTAGS 224
N+ GSF C C D IC++ ID C N + +C ++ G+
Sbjct: 822 KNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGA 881
Query: 225 ------FRCE----CGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
C+ CG G C+DIDEC + G+C NG C N G+++C C G
Sbjct: 882 AWGSPCTLCQVDPICGKGYSRIKG-TQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSG 940
Query: 275 YAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG 334
R + +C CT R D C A G
Sbjct: 941 M--------TLDATGRICLDIRLE-TCFLRYEDEECTLPIAGRHRMDACCCS--VGAAWG 989
Query: 335 ARPCGGGQCRNTVGSYTCTCTDG---LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQ 391
C RNT Y C G KP +DI+EC
Sbjct: 990 TEECEECPMRNT-PEYEELCPRGPGFATKEITNGKPFFKDINEC---------------- 1032
Query: 392 KSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
IP LC G C NTIGSF C+C G+++ E+ CTD DEC + D C
Sbjct: 1033 ----KMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEE-RNCTDIDECRISP-DLCGRGQC 1086
Query: 452 INLPGSFQCRCRDGWRGD---GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
+N PG F+C+C +G+ C D+DEC + C C NT+GS+RC C G++
Sbjct: 1087 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCR-GGVCHNTEGSYRCECPPGHQ 1145
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ +C+DI+EC LC NG C N G Y+C C+ G+ D C+
Sbjct: 1146 LSPN-------ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCV 1196
Score = 190 bits (463), Expect = 1e-47
Identities = 107/306 (34%), Positives = 138/306 (45%), Gaps = 30/306 (9%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC +C +G C N G + C C GY D +CVD+NEC C + C
Sbjct: 2402 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC-NFICK 2460
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NTEGS+ C C GY + + C D+DECA C+ CVNT G F C+C G
Sbjct: 2461 NTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ-FLCVNTIGGFTCKCPPG--FTQ 2517
Query: 238 DRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
SC D +EC+ +C S G C+N G++ C C G++ S R
Sbjct: 2518 HHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGS-SCEDVDECEGNHR 2576
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
CQH C N G Y C+C +G+ C D +EC A CGG C NT+GSY C C
Sbjct: 2577 CQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECL-SAHICGGASCHNTLGSYKCMCPA 2635
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G CQDI+EC Q P C G C NT G ++C
Sbjct: 2636 GFQYEQFSG--GCQDINECG------------------SAQAP--CSYG-CSNTEGGYLC 2672
Query: 417 QCPDGY 422
CP GY
Sbjct: 2673 GCPPGY 2678
Score = 174 bits (423), Expect = 8e-43
Identities = 124/389 (31%), Positives = 172/389 (44%), Gaps = 61/389 (15%)
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
D C LC+ GRC+ T GS+RCEC G +L R C D+DEC C+ G C N
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSYRCECNKGFQL-DLRGECIDVDECE--KNPCAGGECINN 507
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADG 322
G+Y C C GY + ++ C + C+NT GS+HC C G+H+ DG
Sbjct: 508 QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDG 567
Query: 323 RSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTI 382
++C D+DEC+ C G C N GS+ C C G ++ G C+DI+EC
Sbjct: 568 KNCEDMDECS-IRNMCLNGMCINEDGSFKCICKPGFQLASDGR--YCKDINEC------- 617
Query: 383 IMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGT 442
+ P +C G C NT GS+ C+C G +V + G C D T
Sbjct: 618 --------------ETPGICMNGRCVNTDGSYRCECFPGLAVGLD-GRVCVDTH--MRST 660
Query: 443 C-DCHPAADCIN-LPGSF---QCRCRDGWRGDGATCEDVD-------ECLTNNGGCHPRA 490
C + CI L G+ +C C G C+ + L ++G P
Sbjct: 661 CYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG---PGM 717
Query: 491 TCANTDGSFRCLCDTGYKGDGY--GLR-TVCCV-----------YSCVDIDECANDPTLC 536
T A +D + C D +G LR T C+ +CVDI+EC + LC
Sbjct: 718 TSAGSDIN-ECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLC 776
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+NG C NTPG + C C GF D ++C
Sbjct: 777 DNGQCRNTPGSFVCTCPKGFIYKPDLKTC 805
Score = 165 bits (400), Expect = 5e-40
Identities = 89/242 (36%), Positives = 113/242 (46%), Gaps = 8/242 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++NEC P C C+N G + C C GY +C D++EC C C
Sbjct: 2443 VDLNECNQAPKPCNF-ICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNC-QFLC 2500
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G FTC C PG+ S C+D +EC + LC G C NT GSF CEC G L
Sbjct: 2501 VNTIGGFTCKCPPGFTQHHTS--CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSL 2558
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
SC+D+DEC + C +G C+N +G Y+C C +GY Q +
Sbjct: 2559 DQTGSSCEDVDECE-GNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHI 2616
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
SC NT GSY C C G+ C+DI+EC PC G C NT G Y C C
Sbjct: 2617 CGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCP 2675
Query: 356 DG 357
G
Sbjct: 2676 PG 2677
Score = 146 bits (353), Expect = 2e-34
Identities = 76/227 (33%), Positives = 105/227 (46%), Gaps = 9/227 (3%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHT-CVDVNECEIVDGVCGD-GD 175
+++ECA C C N +GGFTC C PG+ +++HT C+D NEC +CG G
Sbjct: 2485 DLDECATKQHNCQF-LCVNTIGGFTCKCPPGF---TQHHTSCIDNNECTSDINLCGSKGI 2540
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C NT GSFTC C+ G+ D C D+DEC N C+ G C N G +RC C G
Sbjct: 2541 CQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQGYLQ 2598
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
C D +EC +++ IC +C N +G+Y+C+C G+
Sbjct: 2599 HYQWNQCVDENEC-LSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQA 2657
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ 342
C + C NT G Y C C G+ G + G P G+
Sbjct: 2658 PCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGE 2704
Score = 132 bits (318), Expect = 4e-30
Identities = 98/341 (28%), Positives = 138/341 (40%), Gaps = 29/341 (8%)
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ-H 299
+C+D+DEC G+C G C N +G+++C C G+ + V C+
Sbjct: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN----TVGSYTCTCT 355
C NT SY C C G++ DG C D+ G+C N ++ C C
Sbjct: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDV-RPGYCYTALTNGRCSNQLPQSITKMQCCCD 361
Query: 356 DGLV--PSAAGAKPTC-----QDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCH 408
G P A C +D ++ + +I + + P P L
Sbjct: 362 AGRCWSPGVTVAPEMCPIRATEDFNKLCS-VPMVIPGRPEYPPPPLGPIPPVLPVPPGFP 420
Query: 409 NTIGSFVCQCPDGY---SVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
V + P Y S +P + D C+L C CI PGS++C C G
Sbjct: 421 PGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGR-CIPTPGSYRCECNKG 479
Query: 466 WRGD-GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
++ D C DVDEC N C C N GS+ C C GY+ RT C
Sbjct: 480 FQLDLRGECIDVDECEKN--PC-AGGECINNQGSYTCQCRAGYQST--LTRT-----ECR 529
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DIDEC + +C NG C NT G + C C+ GF DG++C
Sbjct: 530 DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNC 570
Score = 129 bits (311), Expect = 3e-29
Identities = 83/231 (35%), Positives = 100/231 (43%), Gaps = 39/231 (16%)
Query: 338 CGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
C G+C T GSY C C G G C D+DEC +P
Sbjct: 460 CQNGRCIPTPGSYRCECNKGFQLDLRGE---CIDVDECEK-----------------NP- 498
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
C G C N GS+ CQC GY + C D DEC C+ CIN GS
Sbjct: 499 ----CAGGECINNQGSYTCQCRAGYQSTLTR-TECRDIDECLQNGRICNNGR-CINTDGS 552
Query: 458 FQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
F C C G+ DG CED+DEC N + C N DGSF+C+C G++ G
Sbjct: 553 FHCVCNAGFHVTRDGKNCEDMDECSIRNMCLN--GMCINEDGSFKCICKPGFQLASDGRY 610
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DI+EC P +C NG C NT G Y C+C G DGR C+
Sbjct: 611 -------CKDINECET-PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV 653
Score = 113 bits (273), Expect = 1e-24
Identities = 52/134 (38%), Positives = 74/134 (55%), Gaps = 5/134 (3%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
C G+ + + C DV+EC+ + G+C G+C NT GSF C C G+K ++ S+ C DID
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 290
Query: 205 ECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDI--DEC--SITSGICSNGAC 260
EC+ +C GG C NT S+ C+C G +PD C D+ C ++T+G CSN
Sbjct: 291 ECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSN-QL 349
Query: 261 ENQMGTYQCVCDEG 274
+ QC CD G
Sbjct: 350 PQSITKMQCCCDAG 363
Score = 95.9 bits (228), Expect = 3e-19
Identities = 86/309 (27%), Positives = 119/309 (38%), Gaps = 45/309 (14%)
Query: 136 NLLGG-FTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYK 192
N+ G + C PG++ + C V + DG C + C G C G +
Sbjct: 57 NVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSC--GSR 114
Query: 193 ADDFSKI-CVDIDECADNDALCRGGRCVNTAGSFRCECG---HGMELAPDRLSCKDIDEC 248
+ I C++ C+D+ LC+ G G CE G G +AP+R C
Sbjct: 115 SIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNR--------C 166
Query: 249 SITSGICSNGACENQMGTYQC--VCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHSCVNTP 305
+ T G + CE T C V Q + R H C P
Sbjct: 167 ACTYGF-TGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKQLCCATVGRAWGHPCEMCP 225
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGA 365
H CR G+ +C+D+DEC C GG C NTVGS+ C C G +
Sbjct: 226 AQPH-PCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQ 284
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVK 425
K C+DIDEC+ IP +C G C NT+ S+ C+CP G+
Sbjct: 285 K--CEDIDECS--------------------TIPGICEGGECTNTVSSYFCKCPPGFYTS 322
Query: 426 PEQGPACTD 434
P+ G C D
Sbjct: 323 PD-GTRCID 330
Score = 95.1 bits (226), Expect = 6e-19
Identities = 85/275 (30%), Positives = 107/275 (38%), Gaps = 35/275 (12%)
Query: 297 CQHSCVNTPGSYH--CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+HSC + S CTC G + G R I C R GG C + C C
Sbjct: 85 CRHSCGDGFCSRPNMCTCPSGQIAPSCGS--RSIQHC--NIRCMNGGSCSDD----HCLC 136
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + + G +P C+ C + + PQ G C I +
Sbjct: 137 QKGYIGTHCG-QPVCES--GCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQ 193
Query: 415 VCQCPDGYSVKPEQGPACTDDDECE-LGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT- 472
+CQ G CT C +G HP C P CR G+ + T
Sbjct: 194 MCQ-------GQLSGIVCTKQLCCATVGRAWGHPCEMCPAQPHP----CRRGFIPNIRTG 242
Query: 473 -CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
C+DVDEC G C C NT GSF C C G+K L V C DIDEC+
Sbjct: 243 ACQDVDECQAIPGLCQG-GNCINTVGSFECKCPAGHK-----LNEVS--QKCEDIDECST 294
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P +CE G C+NT Y C C GF + DG C+
Sbjct: 295 IPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCI 329
Score = 91.5 bits (217), Expect = 7e-18
Identities = 39/103 (37%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC A PGLC G C N +G F C C G++ + + C D++EC + G+C G+C
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 305
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVN 220
NT S+ C C PG+ C+D+ AL GRC N
Sbjct: 306 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTAL-TNGRCSN 347
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
GG+CS P + + CCC+ G+ WG+ CE CP + +A++ +C
Sbjct: 2067 GGKCSSPKSRNHSKQECCCALKGEGWGDP-CELCPTEPDEAFRQIC 2111
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C+ P+ CCCS +G AWG + CE CP + T Y+ LC
Sbjct: 967 CTLPIAGRHRMDACCCS-VGAAWGTEECEECPMRNTPEYEELC 1008
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 1 MTGGRCSGPLPTDVLRAVCCCSALGKAWG---NQRCEPCPKKGTDAYQNLCIAVGTLLP 56
+T GRCS LP + + CCC A G+ W E CP + T+ + LC +V ++P
Sbjct: 340 LTNGRCSNQLPQSITKMQCCCDA-GRCWSPGVTVAPEMCPIRATEDFNKLC-SVPMVIP 396
Score = 43.6 bits (98), Expect = 0.002
Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
G+C PL V ++ CCC++ A+G + C+PCP + + YQ LC
Sbjct: 668 GQCIKPLFGAVTKSECCCASTEYAFG-EPCQPCPAQNSAEYQALC 711
Score = 39.1 bits (87), Expect = 0.041
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V ++ CCC G+ WG CE CP +GT A++ LC
Sbjct: 2358 VTKSECCCDG-GRGWG-PHCEICPFQGTVAFKKLC 2390
Score = 34.7 bits (76), Expect = 0.89
Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCP 37
C G L V CC+ +G+AWG+ CE CP
Sbjct: 195 CQGQLSGIVCTKQLCCATVGRAWGHP-CEMCP 225
>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
Length = 2871
Score = 429 bits (1056), Expect = e-119
Identities = 196/449 (43%), Positives = 253/449 (56%), Gaps = 33/449 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NEC P LC HG+CRN +G F C C G+ DS+ C D++EC I +CG G C
Sbjct: 1028 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT G F C C GY++ K C+DIDEC + LCRGG C NT GS+RCEC G +L+
Sbjct: 1088 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS 1147
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
P+ +C DI+EC +++ +C NG C N +G YQC C+ GY + +
Sbjct: 1148 PNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGG 1207
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C+ C N+ GSY C+C+ G+ L D RSC DIDEC C GGQC N G Y C C D
Sbjct: 1208 CETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYD 1267
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A+ TC D++EC DL P +C +G+C NT GSF+C
Sbjct: 1268 GFM--ASEDMKTCVDVNEC-DL-------------------NPNICLSGTCENTKGSFIC 1305
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GYS K + CTD +ECE+G +C A C N GSF+C C GW GDG C D+
Sbjct: 1306 HCDMGYSGKKGK-TGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDL 1364
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC C A C NT GS+RCLC GY GDG ++C D+DEC+ + LC
Sbjct: 1365 DECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDG---------FTCTDLDECSENLNLC 1415
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
NG C N PGGY C+CD+GF +ADG++C
Sbjct: 1416 GNGQCLNAPGGYRCECDMGFVPSADGKAC 1444
Score = 301 bits (740), Expect = 3e-81
Identities = 165/445 (37%), Positives = 219/445 (49%), Gaps = 44/445 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+++EC P LC G C N G + C+C PG++ C+D+NECE+ +C +G C
Sbjct: 1112 MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRC 1171
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G + C C PGY + CVDIDEC+ + C C N+ GS+ C C G L
Sbjct: 1172 VNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCE-TFCTNSEGSYECSCQPGFALM 1230
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXX 295
PD+ SC DIDEC IC G C N G Y+C+C +G+ A +K+
Sbjct: 1231 PDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNI 1290
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTC 354
+C NT GS+ C C G+ + C DI+EC GA CG C NT GS+ C+C
Sbjct: 1291 CLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSC 1350
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGS 413
+ G + G K C D+DEC++ T +C C NT+GS
Sbjct: 1351 SPGWI--GDGIK--CTDLDECSN--GT------------------HMCSQHADCKNTMGS 1386
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGA 471
+ C C +GY+ G CTD DEC C C+N PG ++C C G+ DG
Sbjct: 1387 YRCLCKEGYT---GDGFTCTDLDECSENLNLC-GNGQCLNAPGGYRCECDMGFVPSADGK 1442
Query: 472 TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
CED+DEC N TC N G FRC C+ GY+ D G +C D++EC
Sbjct: 1443 ACEDIDECSLPN--ICVFGTCHNLPGLFRCECEIGYELDRSG-------GNCTDVNECL- 1492
Query: 532 DPTLCENGHCSNTPGGYECDCDVGF 556
DPT C +G+C NTPG Y CDC F
Sbjct: 1493 DPTTCISGNCVNTPGSYICDCPPDF 1517
Score = 291 bits (714), Expect = 4e-78
Identities = 172/506 (33%), Positives = 238/506 (47%), Gaps = 70/506 (13%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++NEC LC +GRC NL+G + C C PGY CVD++EC I++G C + C
Sbjct: 1154 IDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGC-ETFC 1212
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N+EGS+ C C+PG+ + C DIDEC DN +C GG+C N G +RC C G +
Sbjct: 1213 TNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMAS 1272
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
D +C D++EC + IC +G CEN G++ C CD GY+ K+
Sbjct: 1273 EDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHN 1332
Query: 297 C-QHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCT 353
C +H+ C NT GS+ C+C GW DG C D+DEC+ G C C+NT+GSY C
Sbjct: 1333 CGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL 1390
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTI-------------------IMMSVD-ELQKS 393
C +G G TC D+DEC++ ++ + S D + +
Sbjct: 1391 CKEGYT----GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACED 1446
Query: 394 VDP-QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCI 452
+D +P +C G+CHN G F C+C GY + G CTD +EC L C + +C+
Sbjct: 1447 IDECSLPNICVFGTCHNLPGLFRCECEIGYELD-RSGGNCTDVNEC-LDPTTCI-SGNCV 1503
Query: 453 NLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCH----PRA-----TCANTDG----SF 499
N PGS+ C C + + VD T +G C+ PR C+N G
Sbjct: 1504 NTPGSYICDCPPDFELNPTRVGCVD---TRSGNCYLDIRPRGDNGDTACSNEIGVGVSKA 1560
Query: 500 RCLCDTG-----------------YK---GDGYGLRTVCCVYSCVDIDECANDPTLCENG 539
C C G YK G G R DIDEC P LC+ G
Sbjct: 1561 SCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGG 1620
Query: 540 HCSNTPGGYECDCDVGFTRAADGRSC 565
C NT G ++C C G+ D R C
Sbjct: 1621 KCINTFGSFQCRCPTGYYLNEDTRVC 1646
Score = 255 bits (624), Expect = 4e-67
Identities = 184/548 (33%), Positives = 232/548 (42%), Gaps = 82/548 (14%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWDRPID 65
CS + V +A CCCS LGKAWG CE CP T Y+ LC G PN PI
Sbjct: 1549 CSNEIGVGVSKASCCCS-LGKAWGTP-CEMCPAVNTSEYKILCPG-GEGFRPN----PIT 1601
Query: 66 GNMTDIWSQVGGDENGDGYGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNECAAF 125
+ DI DE + G G +VNEC
Sbjct: 1602 VILEDI------DECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET- 1654
Query: 126 PGLCGHGRCRNLL---------------GGFTCD------CFPGYEKDS----------- 153
PG+CG G C N + GG C C+ Y D+
Sbjct: 1655 PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNM 1714
Query: 154 -KNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC---RPGYKADDFSKICVDIDECADN 209
K C N + C +T+ F C RPG+ D ++ + VDIDEC +
Sbjct: 1715 TKKMCCCSYNIGRAWNKPCEQCPIPSTD-EFATLCGSQRPGFVIDIYTGLPVDIDECREI 1773
Query: 210 DALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQ 268
+C G C+N GSFRCEC G L C+DIDEC +C N C N G+Y+
Sbjct: 1774 PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECINTAGSYR 1832
Query: 269 CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH-SCVNTPGSYHCTCREGWHLRADGRSCRD 327
C C GY + T C H C++T GS++C C G+ D C D
Sbjct: 1833 CDCKPGY-RFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLD 1891
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
I+EC A CG G CRNT+GS+ C C G + S C D+DECA
Sbjct: 1892 INECERDA--CGNGTCRNTIGSFNCRCNHGFILS---HNNDCIDVDECAS---------- 1936
Query: 388 DELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
LC G C NT+GSF CQC +GY V P+ G C D +EC L C P
Sbjct: 1937 ---------GNGNLCRNGQCINTVGSFQCQCNEGYEVAPD-GRTCVDINECLLEPRKCAP 1986
Query: 448 AADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
C NL GS++C C G+ CED+DEC+ C TC+NT+GSF+CLC G+
Sbjct: 1987 GT-CQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEIC-ALGTCSNTEGSFKCLCPEGF 2044
Query: 508 KGDGYGLR 515
G R
Sbjct: 2045 SLSSSGRR 2052
Score = 252 bits (617), Expect = 2e-66
Identities = 151/452 (33%), Positives = 217/452 (48%), Gaps = 53/452 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC PG+C +G C N++G F C+C G+ + K C D++EC+ + +C
Sbjct: 1765 VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC 1824
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS+ C C+PGY+ + C D +EC + +C G+C++T GSF C C G +
Sbjct: 1825 INTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTN 1883
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
D+ C DI+EC + C NG C N +G++ C C+ G+ S
Sbjct: 1884 DDQTMCLDINECERDA--CGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNL 1941
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
C++ C+NT GS+ C C EG+ + DGR+C DI+EC R C G C+N GSY C C
Sbjct: 1942 CRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICP 2001
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G S K C+DIDEC V+E PE+C G+C NT GSF
Sbjct: 2002 PGY--SLQNEK--CEDIDEC-----------VEE---------PEICALGTCSNTEGSFK 2037
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCED 475
C CP+G+S+ G C D + C + P S R+ + + C
Sbjct: 2038 CLCPEGFSLS-SSGRRCQD---LRMSYCYAKFEGGKCSSPKS-----RNHSKQE-CCC-- 2085
Query: 476 VDECLTNNGGCHPRATC-ANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
L G P C D +FR +C G G G S VD+DEC +P
Sbjct: 2086 ---ALKGEGWGDPCELCPTEPDEAFRQICPYG-SGIIVGPDD-----SAVDMDEC-KEPD 2135
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C++G C NT G Y C+C G+ A G C+
Sbjct: 2136 VCKHGQCINTDGSYRCECPFGYILA--GNECV 2165
Score = 246 bits (602), Expect = 2e-64
Identities = 155/466 (33%), Positives = 208/466 (44%), Gaps = 73/466 (15%)
Query: 134 CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKA 193
C+NL+G + C C PGY++ CVD NEC+ G+C +G C NT GS+TC C G+ A
Sbjct: 2265 CKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTA 2324
Query: 194 DDFSKICVDIDE--CADN--DALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCK----- 243
C+D E C +C+ G N C C G P C
Sbjct: 2325 SPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTV 2384
Query: 244 -----------------DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
DIDEC + +C NG C N G+Y C+C GY +
Sbjct: 2385 AFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVD 2444
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT 346
C C NT GSY C+C +G+ L+ DGRSC+D+DECA C C NT
Sbjct: 2445 LNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF-LCVNT 2503
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-G 405
+G +TC C G +C D +EC I+ LCG+ G
Sbjct: 2504 IGGFTCKCPPGFTQHHT----SCIDNNECTSDIN--------------------LCGSKG 2539
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C NT GSF C+C G+S+ + G +C D DECE G C C N+ G ++C C G
Sbjct: 2540 ICQNTPGSFTCECQRGFSLD-QTGSSCEDVDECE-GNHRCQHG--CQNIIGGYRCSCPQG 2595
Query: 466 W--RGDGATCEDVDECLTNN--GGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
+ C D +ECL+ + GG A+C NT GS++C+C G++ + +
Sbjct: 2596 YLQHYQWNQCVDENECLSAHICGG----ASCHNTLGSYKCMCPAGFQYEQFS-------G 2644
Query: 522 SCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
C DI+EC + C G SNT GGY C C G+ R G G
Sbjct: 2645 GCQDINECGSAQAPCSYG-SSNTEGGYLCGCPPGYFRIGQGHCVSG 2689
Score = 245 bits (600), Expect = 3e-64
Identities = 155/471 (32%), Positives = 212/471 (45%), Gaps = 42/471 (8%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC P +C G+C N+ G + C C+ G+ TCVDVNEC++ +C G C
Sbjct: 1238 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCE 1297
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELA 236
NT+GSF CHC GY C DI+EC C + C NTAGSF+C C G
Sbjct: 1298 NTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW--I 1355
Query: 237 PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D + C D+DECS + +CS A C+N MG+Y+C+C EGY
Sbjct: 1356 GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTC--TDLDECSENLN 1413
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C + C+N PG Y C C G+ ADG++C DIDEC+ C G C N G + C C
Sbjct: 1414 LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNLPGLFRCEC 1472
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPEL--------C---G 403
G +G C D++EC D + I V+ + P+ C
Sbjct: 1473 EIGYELDRSGGN--CTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTR 1530
Query: 404 AGSCHNTI------GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
+G+C+ I G C G V + C + C+ PA +
Sbjct: 1531 SGNCYLDIRPRGDNGDTACSNEIGVGVS--KASCCCSLGKAWGTPCEMCPAVNTSEY--K 1586
Query: 458 FQCRCRDGWRGDGATC--EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
C +G+R + T ED+DEC G C C NT GSF+C C TGY L
Sbjct: 1587 ILCPGGEGFRPNPITVILEDIDECQELPGLCQG-GKCINTFGSFQCRCPTGYY-----LN 1640
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
V C D++EC P +C G C NT G Y C C + + G +C+
Sbjct: 1641 EDTRV--CDDVNECET-PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCM 1688
Score = 245 bits (599), Expect = 4e-64
Identities = 157/466 (33%), Positives = 210/466 (45%), Gaps = 43/466 (9%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC P +C HG+C N G + C+C GY + CVD +EC V CG+G C
Sbjct: 2126 VDMDECKE-PDVCKHGQCINTDGSYRCECPFGY--ILAGNECVDTDECS-VGNPCGNGTC 2181
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G F C C G++ C DI+ECA N LC RCVNT GS+ C+C G L
Sbjct: 2182 KNVIGGFECTCEEGFEPGPM-MTCEDINECAQNPLLC-AFRCVNTYGSYECKCPVGYVLR 2239
Query: 237 PDRLSCKDIDECSITSGICSNG--ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
DR CKD DEC C+ C+N +GTY C+C GY +
Sbjct: 2240 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2299
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDE--CAGGA--RPCG-GGQCRNTVG 348
C++ C+NT GSY C C +G+ + C D E C C G RN V
Sbjct: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT 2359
Query: 349 SYTCTCTDGLVPSAAGAKPTCQDID-ECADLISTIIMMSVDELQKSVD----PQIPELCG 403
C C G G P C+ + + + D I ++C
Sbjct: 2360 KSECCCDGG-----RGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCR 2414
Query: 404 AGSCHNTIGSFVCQCPDGYSVKPE-QGPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
G C N GS+ C C GY+ P+ G +C D +EC C+ C N GS+QC C
Sbjct: 2415 NGECVNDRGSYHCICKTGYT--PDITGTSCVDLNECNQAPKPCN--FICKNTEGSYQCSC 2470
Query: 463 RDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ + DG +C+D+DEC T C + C NT G F C C G+
Sbjct: 2471 PKGYILQEDGRSCKDLDECATKQHNC--QFLCVNTIGGFTCKCPPGFTQHH--------- 2519
Query: 521 YSCVDIDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
SC+D +EC +D LC G C NTPG + C+C GF+ G SC
Sbjct: 2520 TSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSC 2565
Score = 241 bits (590), Expect = 5e-63
Identities = 139/394 (35%), Positives = 189/394 (47%), Gaps = 22/394 (5%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C LC +GRC G C+C G++ D + C+DV+ECE C G+C N +G
Sbjct: 453 CQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGE-CIDVDECE--KNPCAGGECINNQG 509
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
S+TC CR GY++ C DIDEC N +C GRC+NT GSF C C G + D +
Sbjct: 510 SYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 569
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C+D+DECSI + +C NG C N+ G+++C+C G+ ++ + C
Sbjct: 570 CEDMDECSIRN-MCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRC 628
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDI---DECAGGARPCGGGQC-RNTVGSYT---CTC 354
VNT GSY C C G + DGR C D C GG + GQC + G+ T C C
Sbjct: 629 VNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYK---RGQCIKPLFGAVTKSECCC 685
Query: 355 TDGLVPSAAGAKP-TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
+P Q+ E L S+ M+ + P++C G C N G+
Sbjct: 686 ASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGT 745
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG--WRGDGA 471
+ C C GY V G C D +EC L + C C N PGSF C C G ++ D
Sbjct: 746 YKCICNSGYEV-DSTGKNCVDINECVLNSLLC-DNGQCRNTPGSFVCTCPKGFIYKPDLK 803
Query: 472 TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
TCED+DEC + C C N+ GSF C C +
Sbjct: 804 TCEDIDEC--ESSPC-INGVCKNSPGSFICECSS 834
Score = 241 bits (589), Expect = 6e-63
Identities = 155/461 (33%), Positives = 207/461 (44%), Gaps = 68/461 (14%)
Query: 117 MEVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA+ G LC +G+C N +G F C C GYE TCVD+NEC + C G
Sbjct: 1929 IDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGT 1988
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N +GS+ C C PGY + + C DIDEC + +C G C NT GSF+C C G L
Sbjct: 1989 CQNLDGSYRCICPPGYSLQN--EKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSL 2046
Query: 236 APDRLSCKDI--DEC--SITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ C+D+ C G CS+ N +C C +K
Sbjct: 2047 SSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNH-SKQECCC-------ALKGEGWGDP--- 2095
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWHLRAD-GRSCRDIDECAGGARPCGGGQCRNTVGSY 350
C+ ++ C G + S D+DEC C GQC NT GSY
Sbjct: 2096 -----CELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKE-PDVCKHGQCINTDGSY 2149
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNT 410
C C G + AG + C D DEC+ + CG G+C N
Sbjct: 2150 RCECPFGYI--LAGNE--CVDTDECS---------------------VGNPCGNGTCKNV 2184
Query: 411 IGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RG 468
IG F C C +G+ P C D +EC C A C+N GS++C+C G+ R
Sbjct: 2185 IGGFECTCEEGFEPGPMM--TCEDINECAQNPLLC--AFRCVNTYGSYECKCPVGYVLRE 2240
Query: 469 DGATCEDVDECLTNNGGC-HPRATCANTDGSFRCLCDTGY--KGDGYGLRTVCCVYSCVD 525
D C+D DEC C + C N G++ C+C GY + DG G CVD
Sbjct: 2241 DRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEG---------CVD 2291
Query: 526 IDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+EC P +CENG C NT G Y C+C+ GFT + + CL
Sbjct: 2292 ENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 2332
Score = 239 bits (584), Expect = 2e-62
Identities = 166/508 (32%), Positives = 224/508 (44%), Gaps = 94/508 (18%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDV-----------NECEI 166
+++EC + P C +G C+N G F C+C D C++ CEI
Sbjct: 807 DIDECESSP--CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEI 864
Query: 167 -VDGVCGDGDCHNTEGSF------TCH----CRPGYKADDFSKICVDIDECADNDALCRG 215
++G C ++ G+ C C GY ++ C DIDEC +C+
Sbjct: 865 NINGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQ-CEDIDECEVFPGVCKN 923
Query: 216 GRCVNTAGSFRCECGHGMELAPDRLSCKDI-----------DECSITSG--------ICS 256
G CVNT GSF+C+C GM L C DI +EC++ CS
Sbjct: 924 GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCS 983
Query: 257 NGA------CEN----QMGTYQCVCDEG--YAQSTV---KSHXXXXXXXXXXXXRCQHS- 300
GA CE Y+ +C G +A + K C H
Sbjct: 984 VGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGK 1043
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP 360
C NT GS+ C C G+ L ++ R+C DIDEC CG GQC NT G + C C +G
Sbjct: 1044 CRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYES 1103
Query: 361 SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD 420
K C DIDEC Q+ P LC G CHNT GS+ C+CP
Sbjct: 1104 GFMMMK-NCMDIDEC---------------QRD-----PLLCRGGVCHNTEGSYRCECPP 1142
Query: 421 GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDE 478
G+ + P AC D +ECEL C P C+NL G +QC C G+ D C D+DE
Sbjct: 1143 GHQLSPNIS-ACIDINECELSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1200
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN 538
C NGGC C N++GS+ C C G+ + SC DIDEC ++P +C+
Sbjct: 1201 CSIMNGGCE--TFCTNSEGSYECSCQPGFA-------LMPDQRSCTDIDECEDNPNICDG 1251
Query: 539 GHCSNTPGGYECDCDVGFTRAADGRSCL 566
G C+N PG Y C C GF + D ++C+
Sbjct: 1252 GQCTNIPGEYRCLCYDGFMASEDMKTCV 1279
Score = 239 bits (584), Expect = 2e-62
Identities = 153/480 (31%), Positives = 207/480 (43%), Gaps = 68/480 (14%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++ +EC+ CG+G C+N++GGF C C G+E TC D+NEC +C C
Sbjct: 2165 VDTDECSV-GNPCGNGTCKNVIGGFECTCEEGFEPGPMM-TCEDINECAQNPLLCAFR-C 2221
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC--RGGRCVNTAGSFRCECGHGME 234
NT GS+ C C GY + ++C D DEC + C + C N G++ C CG G +
Sbjct: 2222 VNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQ 2281
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
PD C D +EC GIC NG C N G+Y C C++G+ S +
Sbjct: 2282 RRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFT 2341
Query: 295 XRCQHSCV------NTPGSYHCTCR--EGW--------------------HLRADGRSCR 326
Q+ C N C C GW H R +
Sbjct: 2342 EVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA 2401
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
DIDEC C G+C N GSY C C G P G +C D++EC
Sbjct: 2402 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGT--SCVDLNECN---------- 2449
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCH 446
Q P+ C C NT GS+ C CP GY ++ E G +C D DEC +C
Sbjct: 2450 ----------QAPKPCNF-ICKNTEGSYQCSCPKGYILQ-EDGRSCKDLDECATKQHNCQ 2497
Query: 447 PAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
C+N G F C+C G+ +C D +EC ++ C + C NT GSF C C G
Sbjct: 2498 FL--CVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRG 2555
Query: 507 YKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ D G SC D+DEC + C++G C N GGY C C G+ + C+
Sbjct: 2556 FSLDQTG-------SSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQGYLQHYQWNQCV 2606
Score = 223 bits (546), Expect = 1e-57
Identities = 155/464 (33%), Positives = 202/464 (43%), Gaps = 47/464 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C C GYE DS CVD+NEC + +C +G C
Sbjct: 723 DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCR 782
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT GSF C C G+ K C DIDEC + C G C N+ GSF CEC L P
Sbjct: 783 NTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSSESTLDP 840
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
+ C G C + + C+ +T+KS C
Sbjct: 841 TKTIC-----IETIKGTCWQTVIDGR-------CEININGATLKSQ-CCSSLGAAWGSPC 887
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
C P C +G+ R G C DIDEC C G C NT GS+ C C G
Sbjct: 888 T-LCQVDP-----ICGKGYS-RIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSG 940
Query: 358 LVPSAAGAKPTCQDI--DEC----ADLISTIIMMS---VDELQKSVDPQI-PELCGAGSC 407
+ A G C DI + C D T+ + +D SV E C
Sbjct: 941 MTLDATGR--ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPM 998
Query: 408 HNTIG-SFVCQCPDGYSVK--PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
NT +C G++ K P D +EC++ C C N GSF+CRC
Sbjct: 999 RNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLC-THGKCRNTIGSFKCRCDS 1057
Query: 465 GWRGDG--ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ D C D+DEC + C R C NT G F C CD GY+ G+ + + +
Sbjct: 1058 GFALDSEERNCTDIDECRISPDLC-GRGQCVNTPGDFECKCDEGYE-SGFMM-----MKN 1110
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C+DIDEC DP LC G C NT G Y C+C G + + +C+
Sbjct: 1111 CMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACI 1154
Score = 215 bits (525), Expect = 3e-55
Identities = 153/467 (32%), Positives = 198/467 (42%), Gaps = 63/467 (13%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC +C +GRC N G F C C G+ C D++EC I +C +G C
Sbjct: 530 DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI-RNMCLNGMCI 588
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N +GSF C C+PG++ + C DI+EC + +C GRCVNT GS+RCEC G+ +
Sbjct: 589 NEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRCECFPGLAVGL 647
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
D C D S G G QC+ + + KS C
Sbjct: 648 DGRVCVDTHMRSTCYGGYKRG---------QCI--KPLFGAVTKSECCCASTEYAFGEPC 696
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
Q Y C G + + G DI+ECA C G C N G+Y C C G
Sbjct: 697 QPCPAQNSAEYQALCSSGPGMTSAG---SDINECALDPDICPNGICENLRGTYKCICNSG 753
Query: 358 LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQ 417
+ G C DI+EC ++ S+ LC G C NT GSFVC
Sbjct: 754 YEVDSTG--KNCVDINEC-------VLNSL-------------LCDNGQCRNTPGSFVCT 791
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD-------- 469
CP G+ KP+ C D DECE C C N PGSF C C D
Sbjct: 792 CPKGFIYKPDL-KTCEDIDECESSPC---INGVCKNSPGSFICECSSESTLDPTKTICIE 847
Query: 470 --GATCED--VD-ECLTNNGGCHPRATCANTDGS---FRC-LCDTG-YKGDGYGLRTVCC 519
TC +D C N G ++ C ++ G+ C LC G GY
Sbjct: 848 TIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGT- 906
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DIDEC P +C+NG C NT G ++C C G T A GR CL
Sbjct: 907 --QCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICL 951
Score = 211 bits (516), Expect = 4e-54
Identities = 132/398 (33%), Positives = 177/398 (44%), Gaps = 36/398 (9%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GD 175
++NEC CG H C N G F C C PG+ D C D++EC +C D
Sbjct: 1322 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIK--CTDLDECSNGTHMCSQHAD 1379
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C NT GS+ C C+ GY D F+ C D+DEC++N LC G+C+N G +RCEC G
Sbjct: 1380 CKNTMGSYRCLCKEGYTGDGFT--CTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVP 1437
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C+DIDECS+ + IC G C N G ++C C+ GY +
Sbjct: 1438 SADGKACEDIDECSLPN-ICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTT 1496
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDI--DECAGGARPCGGG---QCRNTVG-- 348
+CVNTPGSY C C + L C D C RP G C N +G
Sbjct: 1497 CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVG 1556
Query: 349 --SYTCTCTDG--------LVP--SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDP 396
+C C+ G + P + + K C + T+I+ +DE Q
Sbjct: 1557 VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQ----- 1611
Query: 397 QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPG 456
++P LC G C NT GSF C+CP GY + E C D +ECE C P C N G
Sbjct: 1612 ELPGLCQGGKCINTFGSFQCRCPTGYYLN-EDTRVCDDVNECETPGI-CGPGT-CYNTVG 1668
Query: 457 SFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATC 492
++ C C + G C D+ L TC
Sbjct: 1669 NYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
Score = 202 bits (494), Expect = 2e-51
Identities = 140/422 (33%), Positives = 194/422 (45%), Gaps = 48/422 (11%)
Query: 157 TCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGG 216
+ VD++EC+ D VC G C NT+GS+ C C GY CVD DEC+ + C G
Sbjct: 2124 SAVDMDECKEPD-VCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNP-CGNG 2179
Query: 217 RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYA 276
C N G F C C G E P ++C+DI+EC+ +C+ C N G+Y+C C GY
Sbjct: 2180 TCKNVIGGFECTCEEGFEPGP-MMTCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYV 2237
Query: 277 QSTVKSHXXXXXXXXXXXXRC---QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAG 333
+ C Q C N G+Y C C G+ R DG C D +EC
Sbjct: 2238 LREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQT 2297
Query: 334 GARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKS 393
C G+C NT GSYTC C DG +A+ + C +D T ++ ++ ++ S
Sbjct: 2298 KPGICENGRCLNTRGSYTCECNDGF--TASPNQDEC--LDNREGYCFTEVLQNMCQIGSS 2353
Query: 394 -VDPQIPELC----GAG---SC-----HNTIGSFVCQCPDGYSVKPEQGPACTDDDECEL 440
+P C G G C T+ +F CP G D DEC++
Sbjct: 2354 NRNPVTKSECCCDGGRGWGPHCEICPFQGTV-AFKKLCPHGRGFMTNG----ADIDECKV 2408
Query: 441 GTCDCHPAADCINLPGSFQCRCRDGWRGD--GATCEDVDECLTNNGGCHPRATCANTDGS 498
C +C+N GS+ C C+ G+ D G +C D++EC C+ C NT+GS
Sbjct: 2409 IHDVCR-NGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN--FICKNTEGS 2465
Query: 499 FRCLCDTGY--KGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
++C C GY + DG SC D+DECA C+ C NT GG+ C C GF
Sbjct: 2466 YQCSCPKGYILQEDG---------RSCKDLDECATKQHNCQ-FLCVNTIGGFTCKCPPGF 2515
Query: 557 TR 558
T+
Sbjct: 2516 TQ 2517
Score = 201 bits (490), Expect = 6e-51
Identities = 144/478 (30%), Positives = 197/478 (41%), Gaps = 73/478 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++NEC LC +G+CRN G F C C G+ TC D++ECE C +G C
Sbjct: 764 VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECE--SSPCINGVC 821
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD----------ID-ECADN-DALCRGGRCVNTAGS 224
N+ GSF C C D IC++ ID C N + +C ++ G+
Sbjct: 822 KNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGA 881
Query: 225 ------FRCE----CGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
C+ CG G C+DIDEC + G+C NG C N G+++C C G
Sbjct: 882 AWGSPCTLCQVDPICGKGYSRIKG-TQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSG 940
Query: 275 YAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG 334
R + +C CT R D C A G
Sbjct: 941 M--------TLDATGRICLDIRLE-TCFLRYEDEECTLPIAGRHRMDACCCS--VGAAWG 989
Query: 335 ARPCGGGQCRNTVGSYTCTCTDG---LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQ 391
C RNT Y C G KP +DI+EC
Sbjct: 990 TEECEECPMRNT-PEYEELCPRGPGFATKEITNGKPFFKDINEC---------------- 1032
Query: 392 KSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
IP LC G C NTIGSF C+C G+++ E+ CTD DEC + D C
Sbjct: 1033 ----KMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEE-RNCTDIDECRISP-DLCGRGQC 1086
Query: 452 INLPGSFQCRCRDGWRGD---GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
+N PG F+C+C +G+ C D+DEC + C C NT+GS+RC C G++
Sbjct: 1087 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCR-GGVCHNTEGSYRCECPPGHQ 1145
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ +C+DI+EC LC NG C N G Y+C C+ G+ D C+
Sbjct: 1146 LSPN-------ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCV 1196
Score = 188 bits (458), Expect = 5e-47
Identities = 107/306 (34%), Positives = 138/306 (45%), Gaps = 30/306 (9%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC +C +G C N G + C C GY D +CVD+NEC C + C
Sbjct: 2402 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC-NFICK 2460
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NTEGS+ C C GY + + C D+DECA C+ CVNT G F C+C G
Sbjct: 2461 NTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ-FLCVNTIGGFTCKCPPG--FTQ 2517
Query: 238 DRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
SC D +EC+ +C S G C+N G++ C C G++ S R
Sbjct: 2518 HHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGS-SCEDVDECEGNHR 2576
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
CQH C N G Y C+C +G+ C D +EC A CGG C NT+GSY C C
Sbjct: 2577 CQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECL-SAHICGGASCHNTLGSYKCMCPA 2635
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G CQDI+EC Q P C GS NT G ++C
Sbjct: 2636 GFQYEQFSG--GCQDINECG------------------SAQAP--CSYGS-SNTEGGYLC 2672
Query: 417 QCPDGY 422
CP GY
Sbjct: 2673 GCPPGY 2678
Score = 172 bits (418), Expect = 3e-42
Identities = 124/389 (31%), Positives = 171/389 (43%), Gaps = 61/389 (15%)
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
D C LC+ GRC+ T GS RCEC G +L R C D+DEC C+ G C N
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQL-DLRGECIDVDECE--KNPCAGGECINN 507
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADG 322
G+Y C C GY + ++ C + C+NT GS+HC C G+H+ DG
Sbjct: 508 QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDG 567
Query: 323 RSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTI 382
++C D+DEC+ C G C N GS+ C C G ++ G C+DI+EC
Sbjct: 568 KNCEDMDECS-IRNMCLNGMCINEDGSFKCICKPGFQLASDGR--YCKDINEC------- 617
Query: 383 IMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGT 442
+ P +C G C NT GS+ C+C G +V + G C D T
Sbjct: 618 --------------ETPGICMNGRCVNTDGSYRCECFPGLAVGLD-GRVCVDTH--MRST 660
Query: 443 C-DCHPAADCIN-LPGSF---QCRCRDGWRGDGATCEDVD-------ECLTNNGGCHPRA 490
C + CI L G+ +C C G C+ + L ++G P
Sbjct: 661 CYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG---PGM 717
Query: 491 TCANTDGSFRCLCDTGYKGDGY--GLR-TVCCV-----------YSCVDIDECANDPTLC 536
T A +D + C D +G LR T C+ +CVDI+EC + LC
Sbjct: 718 TSAGSDIN-ECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLC 776
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+NG C NTPG + C C GF D ++C
Sbjct: 777 DNGQCRNTPGSFVCTCPKGFIYKPDLKTC 805
Score = 161 bits (391), Expect = 6e-39
Identities = 88/242 (36%), Positives = 112/242 (46%), Gaps = 8/242 (3%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++NEC P C C+N G + C C GY +C D++EC C C
Sbjct: 2443 VDLNECNQAPKPCNF-ICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNC-QFLC 2500
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
NT G FTC C PG+ S C+D +EC + LC G C NT GSF CEC G L
Sbjct: 2501 VNTIGGFTCKCPPGFTQHHTS--CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSL 2558
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
SC+D+DEC + C +G C+N +G Y+C C +GY Q +
Sbjct: 2559 DQTGSSCEDVDECE-GNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHI 2616
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
SC NT GSY C C G+ C+DI+EC PC G NT G Y C C
Sbjct: 2617 CGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGS-SNTEGGYLCGCP 2675
Query: 356 DG 357
G
Sbjct: 2676 PG 2677
Score = 142 bits (343), Expect = 4e-33
Identities = 75/227 (33%), Positives = 104/227 (45%), Gaps = 9/227 (3%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHT-CVDVNECEIVDGVCGD-GD 175
+++ECA C C N +GGFTC C PG+ +++HT C+D NEC +CG G
Sbjct: 2485 DLDECATKQHNCQF-LCVNTIGGFTCKCPPGF---TQHHTSCIDNNECTSDINLCGSKGI 2540
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C NT GSFTC C+ G+ D C D+DEC N C+ G C N G +RC C G
Sbjct: 2541 CQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQGYLQ 2598
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
C D +EC +++ IC +C N +G+Y+C+C G+
Sbjct: 2599 HYQWNQCVDENEC-LSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQA 2657
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ 342
C + NT G Y C C G+ G + G P G+
Sbjct: 2658 PCSYGSSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGE 2704
Score = 130 bits (313), Expect = 2e-29
Identities = 98/341 (28%), Positives = 137/341 (40%), Gaps = 29/341 (8%)
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ-H 299
+C+D+DEC G+C G C N +G+++C C G+ + V C+
Sbjct: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN----TVGSYTCTCT 355
C NT SY C C G++ DG C D+ G+C N ++ C C
Sbjct: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDV-RPGYCYTALTNGRCSNQLPQSITKMQCCCD 361
Query: 356 DGLV--PSAAGAKPTC-----QDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCH 408
G P A C +D ++ + +I + + P P L
Sbjct: 362 AGRCWSPGVTVAPEMCPIRATEDFNKLCS-VPMVIPGRPEYPPPPLGPIPPVLPVPPGFP 420
Query: 409 NTIGSFVCQCPDGY---SVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
V + P Y S +P + D C+L C CI PGS +C C G
Sbjct: 421 PGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGR-CIPTPGSCRCECNKG 479
Query: 466 WRGD-GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
++ D C DVDEC N C C N GS+ C C GY+ RT C
Sbjct: 480 FQLDLRGECIDVDECEKN--PC-AGGECINNQGSYTCQCRAGYQST--LTRT-----ECR 529
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DIDEC + +C NG C NT G + C C+ GF DG++C
Sbjct: 530 DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNC 570
Score = 125 bits (302), Expect = 4e-28
Identities = 82/231 (35%), Positives = 99/231 (42%), Gaps = 39/231 (16%)
Query: 338 CGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
C G+C T GS C C G G C D+DEC +P
Sbjct: 460 CQNGRCIPTPGSCRCECNKGFQLDLRGE---CIDVDECEK-----------------NP- 498
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
C G C N GS+ CQC GY + C D DEC C+ CIN GS
Sbjct: 499 ----CAGGECINNQGSYTCQCRAGYQSTLTR-TECRDIDECLQNGRICNNGR-CINTDGS 552
Query: 458 FQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
F C C G+ DG CED+DEC N + C N DGSF+C+C G++ G
Sbjct: 553 FHCVCNAGFHVTRDGKNCEDMDECSIRNMCLN--GMCINEDGSFKCICKPGFQLASDGRY 610
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DI+EC P +C NG C NT G Y C+C G DGR C+
Sbjct: 611 -------CKDINECET-PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV 653
Score = 113 bits (273), Expect = 1e-24
Identities = 52/134 (38%), Positives = 74/134 (55%), Gaps = 5/134 (3%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
C G+ + + C DV+EC+ + G+C G+C NT GSF C C G+K ++ S+ C DID
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 290
Query: 205 ECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDI--DEC--SITSGICSNGAC 260
EC+ +C GG C NT S+ C+C G +PD C D+ C ++T+G CSN
Sbjct: 291 ECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSN-QL 349
Query: 261 ENQMGTYQCVCDEG 274
+ QC CD G
Sbjct: 350 PQSITKMQCCCDAG 363
Score = 96.3 bits (229), Expect = 3e-19
Identities = 86/309 (27%), Positives = 119/309 (38%), Gaps = 45/309 (14%)
Query: 136 NLLGG-FTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYK 192
N+ G + C PG++ + C V + DG C + C G C G +
Sbjct: 57 NVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSC--GSR 114
Query: 193 ADDFSKI-CVDIDECADNDALCRGGRCVNTAGSFRCECG---HGMELAPDRLSCKDIDEC 248
+ I C++ C+D+ LC+ G G CE G G +AP+R C
Sbjct: 115 SIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNR--------C 166
Query: 249 SITSGICSNGACENQMGTYQC--VCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHSCVNTP 305
+ T G + CE T C V Q + R H C P
Sbjct: 167 ACTYGF-TGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCP 225
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGA 365
H CR G+ +C+D+DEC C GG C NTVGS+ C C G +
Sbjct: 226 AQPH-PCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQ 284
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVK 425
K C+DIDEC+ IP +C G C NT+ S+ C+CP G+
Sbjct: 285 K--CEDIDECS--------------------TIPGICEGGECTNTVSSYFCKCPPGFYTS 322
Query: 426 PEQGPACTD 434
P+ G C D
Sbjct: 323 PD-GTRCID 330
Score = 94.7 bits (225), Expect = 8e-19
Identities = 85/275 (30%), Positives = 107/275 (38%), Gaps = 35/275 (12%)
Query: 297 CQHSCVNTPGSYH--CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+HSC + S CTC G + G R I C R GG C + C C
Sbjct: 85 CRHSCGDGFCSRPNMCTCPSGQIAPSCGS--RSIQHC--NIRCMNGGSCSDD----HCLC 136
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + + G +P C+ C + + PQ G C I +
Sbjct: 137 QKGYIGTHCG-QPVCES--GCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQ 193
Query: 415 VCQCPDGYSVKPEQGPACTDDDECE-LGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT- 472
+CQ G CT C +G HP C P CR G+ + T
Sbjct: 194 MCQ-------GQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHP----CRRGFIPNIRTG 242
Query: 473 -CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
C+DVDEC G C C NT GSF C C G+K L V C DIDEC+
Sbjct: 243 ACQDVDECQAIPGLCQG-GNCINTVGSFECKCPAGHK-----LNEVS--QKCEDIDECST 294
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P +CE G C+NT Y C C GF + DG C+
Sbjct: 295 IPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCI 329
Score = 91.5 bits (217), Expect = 7e-18
Identities = 39/103 (37%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC A PGLC G C N +G F C C G++ + + C D++EC + G+C G+C
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 305
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVN 220
NT S+ C C PG+ C+D+ AL GRC N
Sbjct: 306 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTAL-TNGRCSN 347
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
GG+CS P + + CCC+ G+ WG+ CE CP + +A++ +C
Sbjct: 2067 GGKCSSPKSRNHSKQECCCALKGEGWGDP-CELCPTEPDEAFRQIC 2111
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C+ P+ CCCS +G AWG + CE CP + T Y+ LC
Sbjct: 967 CTLPIAGRHRMDACCCS-VGAAWGTEECEECPMRNTPEYEELC 1008
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 1 MTGGRCSGPLPTDVLRAVCCCSALGKAWG---NQRCEPCPKKGTDAYQNLCIAVGTLLP 56
+T GRCS LP + + CCC A G+ W E CP + T+ + LC +V ++P
Sbjct: 340 LTNGRCSNQLPQSITKMQCCCDA-GRCWSPGVTVAPEMCPIRATEDFNKLC-SVPMVIP 396
Score = 43.6 bits (98), Expect = 0.002
Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
G+C PL V ++ CCC++ A+G + C+PCP + + YQ LC
Sbjct: 668 GQCIKPLFGAVTKSECCCASTEYAFG-EPCQPCPAQNSAEYQALC 711
Score = 39.1 bits (87), Expect = 0.041
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V ++ CCC G+ WG CE CP +GT A++ LC
Sbjct: 2358 VTKSECCCDG-GRGWG-PHCEICPFQGTVAFKKLC 2390
Score = 35.5 bits (78), Expect = 0.51
Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCP 37
C G L V CC+ +G+AWG+ CE CP
Sbjct: 195 CQGQLSGIVCTKTLCCATVGRAWGHP-CEMCP 225
>AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth
factor-beta binding protein 4L protein.
Length = 1624
Score = 344 bits (846), Expect = 4e-94
Identities = 175/449 (38%), Positives = 232/449 (51%), Gaps = 41/449 (9%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C P +CG GRC + G+TC C G+ + C+DV+EC V C G C N+ G
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 608
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
SF C C PG++A + C+D+DEC C GRC NT GSF C C G + AP S
Sbjct: 609 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 668
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C+D+DEC+ + G+C GAC+N G+++CVC G+ S + C
Sbjct: 669 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCG--PGRC 726
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
NT GS+HC C G+ R G C+D+DECA PC G+C NT GS+ C C G P+
Sbjct: 727 DNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPN 786
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQ-CPD 420
AAG++ C+D+DEC + ++ C C N+ GSF C+ CP
Sbjct: 787 AAGSE--CEDVDECENHLA---------------------CPGQECVNSPGSFQCRACPS 823
Query: 421 GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR---GDGATCEDVD 477
G+ + +G CTD DEC G C P C N GSF+C C G+R G C DV+
Sbjct: 824 GHHL--HRG-RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVN 880
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
ECL + C P C NTDGSF C C GY+ G SC+D+DEC+ + LC+
Sbjct: 881 ECLEGD-FCFPHGECLNTDGSFACTCAPGYRPGPRGA-------SCLDVDECSEE-DLCQ 931
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+G C+NT G +EC C G D SCL
Sbjct: 932 SGICTNTDGSFECICPPGHRAGPDLASCL 960
Score = 287 bits (705), Expect = 5e-77
Identities = 165/455 (36%), Positives = 211/455 (46%), Gaps = 48/455 (10%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC P C GRC N G F C C PG+ + C+DV+EC V C G C
Sbjct: 586 IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC 645
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C GY+A C D+DEC + LC G C N GSFRC C G +
Sbjct: 646 ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGS 705
Query: 237 PDRLSC-KDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+C +D+DEC+ C G C+N G++ C C G+ +
Sbjct: 706 ----ACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPP 761
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC-T 353
C + C NT GS+ C C G+ A G C D+DEC C G +C N+ GS+ C
Sbjct: 762 PCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECENHL-ACPGQECVNSPGSFQCRA 820
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIG 412
C G + C D+DEC+ P CG G C NT G
Sbjct: 821 CPSG----HHLHRGRCTDVDECS---------------SGAPP-----CGPHGHCTNTEG 856
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD--G 470
SF C C GY + C D +EC G C P +C+N GSF C C G+R G
Sbjct: 857 SFRCSCAPGYRAPSGRPGPCADVNECLEGDF-CFPHGECLNTDGSFACTCAPGYRPGPRG 915
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC- 529
A+C DVDEC + C C NTDGSF C+C G++ G L SC+D+DEC
Sbjct: 916 ASCLDVDEC-SEEDLCQ-SGICTNTDGSFECICPPGHRA-GPDLA------SCLDVDECR 966
Query: 530 ANDPTLCENGHCSNTPGGYEC--DCDVGFTRAADG 562
P LC + C N+PG Y C DCD G+ +G
Sbjct: 967 ERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG 1001
Score = 283 bits (695), Expect = 9e-76
Identities = 166/458 (36%), Positives = 215/458 (46%), Gaps = 47/458 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC PGLCG G C+NL G F C C G+ + DV+EC CG G C
Sbjct: 671 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPPPCGPGRCD 727
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT GSF C C G+++ C D+DECA + C GRC NT GSF+C C G +
Sbjct: 728 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNA 787
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQC-VCDEGYAQSTVKSHXXXXXXXXXXXXR 296
C+D+DEC C C N G++QC C G+ +
Sbjct: 788 AGSECEDVDECE-NHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCG 846
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRS--CRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C NT GS+ C+C G+ + GR C D++EC G G+C NT GS+ CTC
Sbjct: 847 PHGHCTNTEGSFRCSCAPGYRAPS-GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC 905
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G P GA +C D+DEC++ +LC +G C NT GSF
Sbjct: 906 APGYRPGPRGA--SCLDVDECSE---------------------EDLCQSGICTNTDGSF 942
Query: 415 VCQCPDGYSVKPEQGPACTDDDEC-ELGTCDCHPAADCINLPGSFQC--RCRDGWR-GDG 470
C CP G+ P+ +C D DEC E G C + C N PGS++C C G+ G
Sbjct: 943 ECICPPGHRAGPDLA-SCLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPE 1000
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRC--LCDTGYKGDGYGLRTVCCVYSCVDIDE 528
TC+DVDEC C NT GS+RC CD GY+ G C D+DE
Sbjct: 1001 GTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG--------GCQDVDE 1052
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C N + C N PG ++C CD G+ A DGR C+
Sbjct: 1053 CRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV 1090
Score = 273 bits (669), Expect = 1e-72
Identities = 162/444 (36%), Positives = 207/444 (46%), Gaps = 44/444 (9%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+ECA P CG GRC N G F C C G+ C DV+EC C G C
Sbjct: 710 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCE 769
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCE-CGHGMELA 236
NTEGSF C C G++ + C D+DEC +N C G CVN+ GSF+C C G L
Sbjct: 770 NTEGSFQCVCPMGFQPNAAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRACPSGHHLH 828
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
R C D+DECS + C +G C N G+++C C GY + +
Sbjct: 829 RGR--CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD 886
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C C+NT GS+ CTC G+ G SC D+DEC+ C G C NT GS+ C
Sbjct: 887 FCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDL-CQSGICTNTDGSFECI 945
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G A +C D+DEC + + P LCG+ C N+ GS
Sbjct: 946 CPPG--HRAGPDLASCLDVDECRE-------------------RGPALCGSQRCENSPGS 984
Query: 414 FVC--QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR--CRDGWRGD 469
+ C C GY PE C D DEC+ + A C N PGS++C C G++
Sbjct: 985 YRCVRDCDPGYHAGPEG--TCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT 1042
Query: 470 -GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
G C+DVDEC N C A C N GSF+CLCD GY+G G CVD++E
Sbjct: 1043 PGGGCQDVDEC-RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRH-------CVDVNE 1094
Query: 529 CANDPTLCENGHCSNTPGGYECDC 552
C +C C N G + C C
Sbjct: 1095 CETLQGVCGAALCENVEGSFLCVC 1118
Score = 184 bits (447), Expect = 1e-45
Identities = 142/478 (29%), Positives = 194/478 (40%), Gaps = 47/478 (9%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC HG C N G F C C PGY + +C+DV+EC D +C G C
Sbjct: 878 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED-LCQSGICT 936
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADND-ALCRGGRCVNTAGSFRC--ECGHGME 234
NT+GSF C C PG++A C+D+DEC + ALC RC N+ GS+RC +C G
Sbjct: 937 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH 996
Query: 235 LAPDRLSCKDIDECS-ITSGICSNGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXX 291
P+ +C D+DEC IC CEN G+Y+C CD GY +
Sbjct: 997 AGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRN 1055
Query: 292 XXXXRCQHSCVNTPGSYHCTC-------REGWHLRADGRSCRDIDECAGGARPCGGGQ-- 342
C N PGS+ C C R+G H D C + G A C +
Sbjct: 1056 RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCG-AALCENVEGS 1113
Query: 343 ----CRNTVGSYTCTCTDGLVP--SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDP 396
C N+ + T VP ++AG P Q + ++ + S
Sbjct: 1114 FLCVCPNSPEEFD-PMTGRCVPPRTSAGMFPGSQPQAPASPVLPARPPPPPLPRRPSTPR 1172
Query: 397 QIPELCGAGSCH-NTIGSFVCQCPDGYSVKPEQGPACTDDDE----CELGTCDCHPAADC 451
Q P G C+ +T C +V ++ CT + C + C A+
Sbjct: 1173 QGPVGSGRRECYFDTAAPDACDNILARNVTWQEC-CCTVGEGWGSGCRIQQCPGTETAEY 1231
Query: 452 INLPGSFQCRCRDGW---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
+L C G+ GD + DVDEC C NT + C C GY
Sbjct: 1232 QSL-----CPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY 1286
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
Y + + C+D DECA++ CE G C NT G Y C C+ R C+
Sbjct: 1287 ---YHTQRL----ECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 1337
Score = 125 bits (302), Expect = 4e-28
Identities = 65/161 (40%), Positives = 82/161 (50%), Gaps = 8/161 (4%)
Query: 117 MEVNECAAF-PGLCGHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNEC-EIVDGVCG 172
++V+EC P LCG RC N G + C DC PGY + TC DV+EC E +CG
Sbjct: 960 LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICG 1018
Query: 173 DGDCHNTEGSFTCH--CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECG 230
C NT GS+ C C PGY+ C D+DEC + C N GSF+C C
Sbjct: 1019 AQRCENTPGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCLCD 1077
Query: 231 HGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVC 271
G E A D C D++EC G+C CEN G++ CVC
Sbjct: 1078 QGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC 1118
Score = 100 bits (240), Expect = 1e-20
Identities = 54/142 (38%), Positives = 68/142 (47%), Gaps = 14/142 (9%)
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNN 483
PE GP+ C+ C P CI+ P + C C G+R G C DVDEC
Sbjct: 540 PESGPS---SGMCQRNPQVCGPGR-CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVP 595
Query: 484 GGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSN 543
C P C N+ GSFRC+C G++ G R C+D+DEC P C+ G C N
Sbjct: 596 PPCAP-GRCENSPGSFRCVCGPGFRA---GPRAA----ECLDVDECHRVPPPCDLGRCEN 647
Query: 544 TPGGYECDCDVGFTRAADGRSC 565
TPG + C C G+ A G SC
Sbjct: 648 TPGSFLCVCPAGYQAAPHGASC 669
Score = 85.4 bits (202), Expect = 5e-16
Identities = 42/113 (37%), Positives = 58/113 (51%), Gaps = 5/113 (4%)
Query: 160 DVNECEIV-DGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC 218
DV+EC++ D VC G C NT ++C+C GY C+D DECAD + C GGRC
Sbjct: 1253 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1312
Query: 219 VNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVC 271
VNT GS+ C C + L + C + S+ + G C ++G VC
Sbjct: 1313 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL---GVCWQEVGA-DLVC 1361
Score = 81.8 bits (193), Expect = 6e-15
Identities = 36/79 (45%), Positives = 45/79 (56%), Gaps = 4/79 (5%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC---EIVDGVCG 172
++E EC G C +GRC + GFTC CF GY D CVD+NEC E +C
Sbjct: 1531 ELEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1589
Query: 173 DGDCHNTEGSFTCHCRPGY 191
+ C NT+GSF C CRPG+
Sbjct: 1590 NARCLNTDGSFRCICRPGF 1608
Score = 73.3 bits (172), Expect = 2e-12
Identities = 35/77 (45%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDA---LCRG 215
++ EC I+DG C +G C FTC C GY+ D CVDI+EC + +A LC
Sbjct: 1532 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 216 GRCVNTAGSFRCECGHG 232
RC+NT GSFRC C G
Sbjct: 1591 ARCLNTDGSFRCICRPG 1607
Score = 64.9 bits (151), Expect = 7e-10
Identities = 37/115 (32%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 118 EVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC F +C G C N G++C C GY ++ C+D +EC + C G C
Sbjct: 1253 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1312
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
NT GS+ C C P D + CV + + +D L G C G+ C H
Sbjct: 1313 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL---GVCWQEVGA-DLVCSH 1363
Score = 64.9 bits (151), Expect = 7e-10
Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 201 VDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC---SITSGICSN 257
++ +EC D C GRCV F C C G L R++C DI+EC S +C N
Sbjct: 1532 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 258 GACENQMGTYQCVCDEGYAQSTVKSH 283
C N G+++C+C G+A + H
Sbjct: 1591 ARCLNTDGSFRCICRPGFAPTHQPHH 1616
Score = 57.2 bits (132), Expect = 1e-07
Identities = 29/73 (39%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA--TCEDVDECLTNNGGCH--PRATCAN 494
E G D C+ +P F CRC DG+R D C D++EC A C N
Sbjct: 1536 ECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLN 1595
Query: 495 TDGSFRCLCDTGY 507
TDGSFRC+C G+
Sbjct: 1596 TDGSFRCICRPGF 1608
Score = 54.0 bits (124), Expect = 1e-06
Identities = 25/48 (52%), Positives = 30/48 (62%), Gaps = 3/48 (6%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C G+ R +G SC D+DECA G R C G+C NT G YTC C DG +
Sbjct: 344 CPTGFE-RVNG-SCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFL 388
Score = 53.6 bits (123), Expect = 2e-06
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDEC--AGGARP-CGGGQCRNTVGSYTCTCTDG 357
CV P + C C +G+ L +C DI+EC A A P C +C NT GS+ C C G
Sbjct: 1548 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1607
Query: 358 LVPS 361
P+
Sbjct: 1608 FAPT 1611
Score = 52.8 bits (121), Expect = 3e-06
Identities = 19/47 (40%), Positives = 32/47 (68%), Gaps = 1/47 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIA 50
G CS P+ ++ + +CCCS +GKAWG + C+ CP G++ ++ +C A
Sbjct: 416 GGCSLPILRNITKQICCCSRVGKAWG-RGCQLCPPFGSEGFREICPA 461
Score = 50.8 bits (116), Expect = 1e-05
Identities = 21/47 (44%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 522 SCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
SC D+DECA C++G C+NT GGY C C GF + SC+ +
Sbjct: 354 SCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQ 399
Score = 49.2 bits (112), Expect = 4e-05
Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS 282
SC+D+DEC+ T G C +G C N G Y CVC +G+ + +S
Sbjct: 354 SCEDVDECA-TGGRCQHGECANTRGGYTCVCPDGFLLDSSRS 394
Score = 48.4 bits (110), Expect = 7e-05
Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 5/63 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC----GD 173
+V+ECA G C HG C N GG+TC C G+ DS +C+ + G C D
Sbjct: 357 DVDECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRD 415
Query: 174 GDC 176
G C
Sbjct: 416 GGC 418
Score = 48.0 bits (109), Expect = 9e-05
Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICV 201
C G+E+ N +C DV+EC G C G+C NT G +TC C G+ D C+
Sbjct: 344 CPTGFER--VNGSCEDVDECA-TGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI 397
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 3/69 (4%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C G++ + S C D+DECA C+ G C NT G + C C G L R SC
Sbjct: 344 CPTGFERVNGS--CEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 400
Query: 247 ECSITSGIC 255
S G C
Sbjct: 401 VISEAKGPC 409
Score = 46.0 bits (104), Expect = 4e-04
Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 462 CRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
C G+ +CEDVDEC T GG CANT G + C+C G+
Sbjct: 344 CPTGFERVNGSCEDVDECAT--GGRCQHGECANTRGGYTCVCPDGF 387
Score = 46.0 bits (104), Expect = 4e-04
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 14/95 (14%)
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC----A 530
+ +EC +G + R C F C C GY+ D + +CVDI+EC A
Sbjct: 1533 EAEECGILDGCTNGR--CVRVPEGFTCRCFDGYRLDMTRM-------ACVDINECDEAEA 1583
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
P LC N C NT G + C C GF C
Sbjct: 1584 ASP-LCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 45.6 bits (103), Expect = 5e-04
Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC---ELGTCDCHPAADCINLPGSF 458
C G C F C+C DGY + + AC D +EC E + C A C+N GSF
Sbjct: 1543 CTNGRCVRVPEGFTCRCFDGYRLDMTR-MACVDINECDEAEAASPLC-VNARCLNTDGSF 1600
Query: 459 QCRCRDGW 466
+C CR G+
Sbjct: 1601 RCICRPGF 1608
Score = 37.9 bits (84), Expect = 0.095
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 5/46 (10%)
Query: 117 MEVNEC----AAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC 158
+++NEC AA P LC + RC N G F C C PG+ + H C
Sbjct: 1573 VDINECDEAEAASP-LCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 37.1 bits (82), Expect = 0.17
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 1 MTGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKK 39
+ GG C+ PLP + VCC A G AWG C+ C ++
Sbjct: 293 LRGGECASPLPGLRTQEVCCRGA-GLAWGVHDCQLCSER 330
Score = 37.1 bits (82), Expect = 0.17
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC 338
RCQH C NT G Y C C +G+ L + SC + PC
Sbjct: 366 RCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 409
Score = 36.3 bits (80), Expect = 0.29
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 2/44 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQ-RCEPCPKKGTDAYQNLC 48
C L +V CCC+ +G+ WG+ R + CP T YQ+LC
Sbjct: 1193 CDNILARNVTWQECCCT-VGEGWGSGCRIQQCPGTETAEYQSLC 1235
Score = 34.3 bits (75), Expect = 1.2
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Query: 6 CSGP-LPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPP 57
CS P L CCC G+AWG C CP + +D ++ LC L PP
Sbjct: 1361 CSHPRLDRQATYTECCC-LYGEAWG-MDCALCPAQDSDDFEALC---NVLRPP 1408
Score = 33.5 bits (73), Expect = 2.0
Identities = 18/54 (33%), Positives = 24/54 (44%), Gaps = 5/54 (9%)
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
CP G+ +C D DEC G H +C N G + C C DG+ D +
Sbjct: 344 CPTGFE---RVNGSCEDVDECATGGRCQH--GECANTRGGYTCVCPDGFLLDSS 392
Score = 33.5 bits (73), Expect = 2.0
Identities = 11/21 (52%), Positives = 13/21 (61%)
Query: 402 CGAGSCHNTIGSFVCQCPDGY 422
C G C NT G + C CPDG+
Sbjct: 367 CQHGECANTRGGYTCVCPDGF 387
>AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth
factor-beta binding protein 4S protein.
Length = 1557
Score = 344 bits (846), Expect = 4e-94
Identities = 175/449 (38%), Positives = 232/449 (51%), Gaps = 41/449 (9%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C P +CG GRC + G+TC C G+ + C+DV+EC V C G C N+ G
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
SF C C PG++A + C+D+DEC C GRC NT GSF C C G + AP S
Sbjct: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 601
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C+D+DEC+ + G+C GAC+N G+++CVC G+ S + C
Sbjct: 602 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCG--PGRC 659
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
NT GS+HC C G+ R G C+D+DECA PC G+C NT GS+ C C G P+
Sbjct: 660 DNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPN 719
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQ-CPD 420
AAG++ C+D+DEC + ++ C C N+ GSF C+ CP
Sbjct: 720 AAGSE--CEDVDECENHLA---------------------CPGQECVNSPGSFQCRACPS 756
Query: 421 GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR---GDGATCEDVD 477
G+ + +G CTD DEC G C P C N GSF+C C G+R G C DV+
Sbjct: 757 GHHL--HRG-RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVN 813
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
ECL + C P C NTDGSF C C GY+ G SC+D+DEC+ + LC+
Sbjct: 814 ECLEGD-FCFPHGECLNTDGSFACTCAPGYRPGPRGA-------SCLDVDECSEE-DLCQ 864
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+G C+NT G +EC C G D SCL
Sbjct: 865 SGICTNTDGSFECICPPGHRAGPDLASCL 893
Score = 287 bits (705), Expect = 5e-77
Identities = 165/455 (36%), Positives = 211/455 (46%), Gaps = 48/455 (10%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC P C GRC N G F C C PG+ + C+DV+EC V C G C
Sbjct: 519 IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC 578
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C GY+A C D+DEC + LC G C N GSFRC C G +
Sbjct: 579 ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGS 638
Query: 237 PDRLSC-KDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+C +D+DEC+ C G C+N G++ C C G+ +
Sbjct: 639 ----ACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPP 694
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC-T 353
C + C NT GS+ C C G+ A G C D+DEC C G +C N+ GS+ C
Sbjct: 695 PCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECENHL-ACPGQECVNSPGSFQCRA 753
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIG 412
C G + C D+DEC+ P CG G C NT G
Sbjct: 754 CPSG----HHLHRGRCTDVDECS---------------SGAPP-----CGPHGHCTNTEG 789
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD--G 470
SF C C GY + C D +EC G C P +C+N GSF C C G+R G
Sbjct: 790 SFRCSCAPGYRAPSGRPGPCADVNECLEGDF-CFPHGECLNTDGSFACTCAPGYRPGPRG 848
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC- 529
A+C DVDEC + C C NTDGSF C+C G++ G L SC+D+DEC
Sbjct: 849 ASCLDVDEC-SEEDLCQ-SGICTNTDGSFECICPPGHRA-GPDLA------SCLDVDECR 899
Query: 530 ANDPTLCENGHCSNTPGGYEC--DCDVGFTRAADG 562
P LC + C N+PG Y C DCD G+ +G
Sbjct: 900 ERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG 934
Score = 283 bits (695), Expect = 9e-76
Identities = 166/458 (36%), Positives = 215/458 (46%), Gaps = 47/458 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC PGLCG G C+NL G F C C G+ + DV+EC CG G C
Sbjct: 604 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPPPCGPGRCD 660
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT GSF C C G+++ C D+DECA + C GRC NT GSF+C C G +
Sbjct: 661 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNA 720
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQC-VCDEGYAQSTVKSHXXXXXXXXXXXXR 296
C+D+DEC C C N G++QC C G+ +
Sbjct: 721 AGSECEDVDECE-NHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCG 779
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRS--CRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C NT GS+ C+C G+ + GR C D++EC G G+C NT GS+ CTC
Sbjct: 780 PHGHCTNTEGSFRCSCAPGYRAPS-GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC 838
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G P GA +C D+DEC++ +LC +G C NT GSF
Sbjct: 839 APGYRPGPRGA--SCLDVDECSE---------------------EDLCQSGICTNTDGSF 875
Query: 415 VCQCPDGYSVKPEQGPACTDDDEC-ELGTCDCHPAADCINLPGSFQC--RCRDGWR-GDG 470
C CP G+ P+ +C D DEC E G C + C N PGS++C C G+ G
Sbjct: 876 ECICPPGHRAGPDLA-SCLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPE 933
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRC--LCDTGYKGDGYGLRTVCCVYSCVDIDE 528
TC+DVDEC C NT GS+RC CD GY+ G C D+DE
Sbjct: 934 GTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG--------GCQDVDE 985
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C N + C N PG ++C CD G+ A DGR C+
Sbjct: 986 CRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV 1023
Score = 273 bits (669), Expect = 1e-72
Identities = 162/444 (36%), Positives = 207/444 (46%), Gaps = 44/444 (9%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+ECA P CG GRC N G F C C G+ C DV+EC C G C
Sbjct: 643 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCE 702
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCE-CGHGMELA 236
NTEGSF C C G++ + C D+DEC +N C G CVN+ GSF+C C G L
Sbjct: 703 NTEGSFQCVCPMGFQPNAAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRACPSGHHLH 761
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
R C D+DECS + C +G C N G+++C C GY + +
Sbjct: 762 RGR--CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD 819
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C C+NT GS+ CTC G+ G SC D+DEC+ C G C NT GS+ C
Sbjct: 820 FCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDL-CQSGICTNTDGSFECI 878
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G A +C D+DEC + + P LCG+ C N+ GS
Sbjct: 879 CPPG--HRAGPDLASCLDVDECRE-------------------RGPALCGSQRCENSPGS 917
Query: 414 FVC--QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR--CRDGWRGD 469
+ C C GY PE C D DEC+ + A C N PGS++C C G++
Sbjct: 918 YRCVRDCDPGYHAGPEG--TCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT 975
Query: 470 -GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
G C+DVDEC N C A C N GSF+CLCD GY+G G CVD++E
Sbjct: 976 PGGGCQDVDEC-RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRH-------CVDVNE 1027
Query: 529 CANDPTLCENGHCSNTPGGYECDC 552
C +C C N G + C C
Sbjct: 1028 CETLQGVCGAALCENVEGSFLCVC 1051
Score = 184 bits (447), Expect = 1e-45
Identities = 142/478 (29%), Positives = 194/478 (40%), Gaps = 47/478 (9%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC HG C N G F C C PGY + +C+DV+EC D +C G C
Sbjct: 811 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED-LCQSGICT 869
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADND-ALCRGGRCVNTAGSFRC--ECGHGME 234
NT+GSF C C PG++A C+D+DEC + ALC RC N+ GS+RC +C G
Sbjct: 870 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH 929
Query: 235 LAPDRLSCKDIDECS-ITSGICSNGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXX 291
P+ +C D+DEC IC CEN G+Y+C CD GY +
Sbjct: 930 AGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRN 988
Query: 292 XXXXRCQHSCVNTPGSYHCTC-------REGWHLRADGRSCRDIDECAGGARPCGGGQ-- 342
C N PGS+ C C R+G H D C + G A C +
Sbjct: 989 RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCG-AALCENVEGS 1046
Query: 343 ----CRNTVGSYTCTCTDGLVP--SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDP 396
C N+ + T VP ++AG P Q + ++ + S
Sbjct: 1047 FLCVCPNSPEEFD-PMTGRCVPPRTSAGMFPGSQPQAPASPVLPARPPPPPLPRRPSTPR 1105
Query: 397 QIPELCGAGSCH-NTIGSFVCQCPDGYSVKPEQGPACTDDDE----CELGTCDCHPAADC 451
Q P G C+ +T C +V ++ CT + C + C A+
Sbjct: 1106 QGPVGSGRRECYFDTAAPDACDNILARNVTWQEC-CCTVGEGWGSGCRIQQCPGTETAEY 1164
Query: 452 INLPGSFQCRCRDGW---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
+L C G+ GD + DVDEC C NT + C C GY
Sbjct: 1165 QSL-----CPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY 1219
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
Y + + C+D DECA++ CE G C NT G Y C C+ R C+
Sbjct: 1220 ---YHTQRL----ECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 1270
Score = 125 bits (302), Expect = 4e-28
Identities = 65/161 (40%), Positives = 82/161 (50%), Gaps = 8/161 (4%)
Query: 117 MEVNECAAF-PGLCGHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNEC-EIVDGVCG 172
++V+EC P LCG RC N G + C DC PGY + TC DV+EC E +CG
Sbjct: 893 LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICG 951
Query: 173 DGDCHNTEGSFTCH--CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECG 230
C NT GS+ C C PGY+ C D+DEC + C N GSF+C C
Sbjct: 952 AQRCENTPGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCLCD 1010
Query: 231 HGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVC 271
G E A D C D++EC G+C CEN G++ CVC
Sbjct: 1011 QGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC 1051
Score = 100 bits (240), Expect = 1e-20
Identities = 54/142 (38%), Positives = 68/142 (47%), Gaps = 14/142 (9%)
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNN 483
PE GP+ C+ C P CI+ P + C C G+R G C DVDEC
Sbjct: 473 PESGPS---SGMCQRNPQVCGPGR-CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVP 528
Query: 484 GGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSN 543
C P C N+ GSFRC+C G++ G R C+D+DEC P C+ G C N
Sbjct: 529 PPCAP-GRCENSPGSFRCVCGPGFRA---GPRAA----ECLDVDECHRVPPPCDLGRCEN 580
Query: 544 TPGGYECDCDVGFTRAADGRSC 565
TPG + C C G+ A G SC
Sbjct: 581 TPGSFLCVCPAGYQAAPHGASC 602
Score = 85.4 bits (202), Expect = 5e-16
Identities = 42/113 (37%), Positives = 58/113 (51%), Gaps = 5/113 (4%)
Query: 160 DVNECEIV-DGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC 218
DV+EC++ D VC G C NT ++C+C GY C+D DECAD + C GGRC
Sbjct: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1245
Query: 219 VNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVC 271
VNT GS+ C C + L + C + S+ + G C ++G VC
Sbjct: 1246 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL---GVCWQEVGA-DLVC 1294
Score = 81.8 bits (193), Expect = 6e-15
Identities = 36/79 (45%), Positives = 45/79 (56%), Gaps = 4/79 (5%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC---EIVDGVCG 172
++E EC G C +GRC + GFTC CF GY D CVD+NEC E +C
Sbjct: 1464 ELEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
Query: 173 DGDCHNTEGSFTCHCRPGY 191
+ C NT+GSF C CRPG+
Sbjct: 1523 NARCLNTDGSFRCICRPGF 1541
Score = 73.3 bits (172), Expect = 2e-12
Identities = 35/77 (45%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDA---LCRG 215
++ EC I+DG C +G C FTC C GY+ D CVDI+EC + +A LC
Sbjct: 1465 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 216 GRCVNTAGSFRCECGHG 232
RC+NT GSFRC C G
Sbjct: 1524 ARCLNTDGSFRCICRPG 1540
Score = 64.9 bits (151), Expect = 7e-10
Identities = 37/115 (32%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 118 EVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC F +C G C N G++C C GY ++ C+D +EC + C G C
Sbjct: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1245
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
NT GS+ C C P D + CV + + +D L G C G+ C H
Sbjct: 1246 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL---GVCWQEVGA-DLVCSH 1296
Score = 64.9 bits (151), Expect = 7e-10
Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 201 VDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC---SITSGICSN 257
++ +EC D C GRCV F C C G L R++C DI+EC S +C N
Sbjct: 1465 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 258 GACENQMGTYQCVCDEGYAQSTVKSH 283
C N G+++C+C G+A + H
Sbjct: 1524 ARCLNTDGSFRCICRPGFAPTHQPHH 1549
Score = 57.2 bits (132), Expect = 1e-07
Identities = 29/73 (39%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA--TCEDVDECLTNNGGCH--PRATCAN 494
E G D C+ +P F CRC DG+R D C D++EC A C N
Sbjct: 1469 ECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLN 1528
Query: 495 TDGSFRCLCDTGY 507
TDGSFRC+C G+
Sbjct: 1529 TDGSFRCICRPGF 1541
Score = 54.0 bits (124), Expect = 1e-06
Identities = 25/48 (52%), Positives = 30/48 (62%), Gaps = 3/48 (6%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C G+ R +G SC D+DECA G R C G+C NT G YTC C DG +
Sbjct: 277 CPTGFE-RVNG-SCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFL 321
Score = 53.6 bits (123), Expect = 2e-06
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDEC--AGGARP-CGGGQCRNTVGSYTCTCTDG 357
CV P + C C +G+ L +C DI+EC A A P C +C NT GS+ C C G
Sbjct: 1481 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1540
Query: 358 LVPS 361
P+
Sbjct: 1541 FAPT 1544
Score = 52.8 bits (121), Expect = 3e-06
Identities = 19/47 (40%), Positives = 32/47 (68%), Gaps = 1/47 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIA 50
G CS P+ ++ + +CCCS +GKAWG + C+ CP G++ ++ +C A
Sbjct: 349 GGCSLPILRNITKQICCCSRVGKAWG-RGCQLCPPFGSEGFREICPA 394
Score = 50.8 bits (116), Expect = 1e-05
Identities = 21/47 (44%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 522 SCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
SC D+DECA C++G C+NT GGY C C GF + SC+ +
Sbjct: 287 SCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQ 332
Score = 49.2 bits (112), Expect = 4e-05
Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS 282
SC+D+DEC+ T G C +G C N G Y CVC +G+ + +S
Sbjct: 287 SCEDVDECA-TGGRCQHGECANTRGGYTCVCPDGFLLDSSRS 327
Score = 48.4 bits (110), Expect = 7e-05
Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 5/63 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC----GD 173
+V+ECA G C HG C N GG+TC C G+ DS +C+ + G C D
Sbjct: 290 DVDECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRD 348
Query: 174 GDC 176
G C
Sbjct: 349 GGC 351
Score = 48.0 bits (109), Expect = 9e-05
Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICV 201
C G+E+ N +C DV+EC G C G+C NT G +TC C G+ D C+
Sbjct: 277 CPTGFER--VNGSCEDVDECA-TGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI 330
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 3/69 (4%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C G++ + S C D+DECA C+ G C NT G + C C G L R SC
Sbjct: 277 CPTGFERVNGS--CEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 333
Query: 247 ECSITSGIC 255
S G C
Sbjct: 334 VISEAKGPC 342
Score = 46.0 bits (104), Expect = 4e-04
Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 462 CRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
C G+ +CEDVDEC T GG CANT G + C+C G+
Sbjct: 277 CPTGFERVNGSCEDVDECAT--GGRCQHGECANTRGGYTCVCPDGF 320
Score = 46.0 bits (104), Expect = 4e-04
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 14/95 (14%)
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC----A 530
+ +EC +G + R C F C C GY+ D + +CVDI+EC A
Sbjct: 1466 EAEECGILDGCTNGR--CVRVPEGFTCRCFDGYRLDMTRM-------ACVDINECDEAEA 1516
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
P LC N C NT G + C C GF C
Sbjct: 1517 ASP-LCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 45.6 bits (103), Expect = 5e-04
Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC---ELGTCDCHPAADCINLPGSF 458
C G C F C+C DGY + + AC D +EC E + C A C+N GSF
Sbjct: 1476 CTNGRCVRVPEGFTCRCFDGYRLDMTR-MACVDINECDEAEAASPLC-VNARCLNTDGSF 1533
Query: 459 QCRCRDGW 466
+C CR G+
Sbjct: 1534 RCICRPGF 1541
Score = 37.9 bits (84), Expect = 0.095
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 5/46 (10%)
Query: 117 MEVNEC----AAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC 158
+++NEC AA P LC + RC N G F C C PG+ + H C
Sbjct: 1506 VDINECDEAEAASP-LCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 37.1 bits (82), Expect = 0.17
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 1 MTGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKK 39
+ GG C+ PLP + VCC A G AWG C+ C ++
Sbjct: 226 LRGGECASPLPGLRTQEVCCRGA-GLAWGVHDCQLCSER 263
Score = 37.1 bits (82), Expect = 0.17
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC 338
RCQH C NT G Y C C +G+ L + SC + PC
Sbjct: 299 RCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 342
Score = 36.3 bits (80), Expect = 0.29
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 2/44 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQ-RCEPCPKKGTDAYQNLC 48
C L +V CCC+ +G+ WG+ R + CP T YQ+LC
Sbjct: 1126 CDNILARNVTWQECCCT-VGEGWGSGCRIQQCPGTETAEYQSLC 1168
Score = 34.3 bits (75), Expect = 1.2
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Query: 6 CSGP-LPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPP 57
CS P L CCC G+AWG C CP + +D ++ LC L PP
Sbjct: 1294 CSHPRLDRQATYTECCC-LYGEAWG-MDCALCPAQDSDDFEALC---NVLRPP 1341
Score = 33.5 bits (73), Expect = 2.0
Identities = 18/54 (33%), Positives = 24/54 (44%), Gaps = 5/54 (9%)
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
CP G+ +C D DEC G H +C N G + C C DG+ D +
Sbjct: 277 CPTGFE---RVNGSCEDVDECATGGRCQH--GECANTRGGYTCVCPDGFLLDSS 325
Score = 33.5 bits (73), Expect = 2.0
Identities = 11/21 (52%), Positives = 13/21 (61%)
Query: 402 CGAGSCHNTIGSFVCQCPDGY 422
C G C NT G + C CPDG+
Sbjct: 300 CQHGECANTRGGYTCVCPDGF 320
>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
protein-4 protein.
Length = 1587
Score = 341 bits (838), Expect = 4e-93
Identities = 173/449 (38%), Positives = 230/449 (51%), Gaps = 41/449 (9%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C P +CG GRC + G+TC C G+ + C+DV+EC V C G C N+ G
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 571
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
SF C C PG++A + C+D+DEC C GRC NT GSF C C G + AP S
Sbjct: 572 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 631
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C+D+DEC+ + G+C G C+N G+++CVC G+ S + C
Sbjct: 632 CQDVDECTQSPGLCGRGGCKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCG--PGRC 689
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
NT GS+HC C G+ R G C+D+DECA PC G+C NT GS+ C C G P+
Sbjct: 690 DNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPN 749
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQ-CPD 420
AG++ C+D+DEC + ++ C C N+ GSF C+ CP
Sbjct: 750 TAGSE--CEDVDECENHLA---------------------CPGQECVNSPGSFQCRTCPS 786
Query: 421 GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR---GDGATCEDVD 477
G+ + +G CTD DEC G C P C N GSF+C C G+R G C DV+
Sbjct: 787 GHHL--HRG-RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVN 843
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
ECL + C P C NTDGSF C C GY+ G SC+D+DEC+ + LC+
Sbjct: 844 ECLEGD-FCFPHGECLNTDGSFACTCAPGYRPGPRGA-------SCLDVDECSEE-DLCQ 894
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+G C+NT G +EC C G D SCL
Sbjct: 895 SGICTNTDGSFECICPPGHRAGPDLASCL 923
Score = 287 bits (705), Expect = 5e-77
Identities = 165/455 (36%), Positives = 211/455 (46%), Gaps = 48/455 (10%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC P C GRC N G F C C PG+ + C+DV+EC V C G C
Sbjct: 549 IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC 608
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C GY+A C D+DEC + LC G C N GSFRC C G +
Sbjct: 609 ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGGCKNLPGSFRCVCPAGFRGS 668
Query: 237 PDRLSC-KDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+C +D+DEC+ C G C+N G++ C C G+ +
Sbjct: 669 ----ACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPP 724
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC-T 353
C + C NT GS+ C C G+ G C D+DEC C G +C N+ GS+ C T
Sbjct: 725 PCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHL-ACPGQECVNSPGSFQCRT 783
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIG 412
C G + C D+DEC+ P CG G C NT G
Sbjct: 784 CPSG----HHLHRGRCTDVDECS---------------SGAPP-----CGPHGHCTNTEG 819
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD--G 470
SF C C GY + C D +EC G C P +C+N GSF C C G+R G
Sbjct: 820 SFRCSCAPGYRAPSGRPGPCADVNECLEGDF-CFPHGECLNTDGSFACTCAPGYRPGPRG 878
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC- 529
A+C DVDEC + C C NTDGSF C+C G++ G L SC+D+DEC
Sbjct: 879 ASCLDVDEC-SEEDLCQ-SGICTNTDGSFECICPPGHRA-GPDLA------SCLDVDECR 929
Query: 530 ANDPTLCENGHCSNTPGGYEC--DCDVGFTRAADG 562
P LC + C N+PG Y C DCD G+ +G
Sbjct: 930 ERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG 964
Score = 283 bits (694), Expect = 1e-75
Identities = 166/458 (36%), Positives = 215/458 (46%), Gaps = 47/458 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC PGLCG G C+NL G F C C G+ + DV+EC CG G C
Sbjct: 634 DVDECTQSPGLCGRGGCKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPPPCGPGRCD 690
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT GSF C C G+++ C D+DECA + C GRC NT GSF+C C G +
Sbjct: 691 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT 750
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQC-VCDEGYAQSTVKSHXXXXXXXXXXXXR 296
C+D+DEC C C N G++QC C G+ +
Sbjct: 751 AGSECEDVDECE-NHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCG 809
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRS--CRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C NT GS+ C+C G+ + GR C D++EC G G+C NT GS+ CTC
Sbjct: 810 PHGHCTNTEGSFRCSCAPGYRAPS-GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC 868
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G P GA +C D+DEC++ +LC +G C NT GSF
Sbjct: 869 APGYRPGPRGA--SCLDVDECSE---------------------EDLCQSGICTNTDGSF 905
Query: 415 VCQCPDGYSVKPEQGPACTDDDEC-ELGTCDCHPAADCINLPGSFQC--RCRDGWR-GDG 470
C CP G+ P+ +C D DEC E G C + C N PGS++C C G+ G
Sbjct: 906 ECICPPGHRAGPDLA-SCLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPE 963
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRC--LCDTGYKGDGYGLRTVCCVYSCVDIDE 528
TC+DVDEC C NT GS+RC CD GY+ G C D+DE
Sbjct: 964 GTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG--------GCQDVDE 1015
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C N + C N PG ++C CD G+ A DGR C+
Sbjct: 1016 CRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV 1053
Score = 273 bits (670), Expect = 9e-73
Identities = 162/444 (36%), Positives = 207/444 (46%), Gaps = 44/444 (9%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+ECA P CG GRC N G F C C G+ C DV+EC C G C
Sbjct: 673 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCE 732
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCE-CGHGMELA 236
NTEGSF C C G++ + C D+DEC +N C G CVN+ GSF+C C G L
Sbjct: 733 NTEGSFQCVCPMGFQPNTAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRTCPSGHHLH 791
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
R C D+DECS + C +G C N G+++C C GY + +
Sbjct: 792 RGR--CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD 849
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C C+NT GS+ CTC G+ G SC D+DEC+ C G C NT GS+ C
Sbjct: 850 FCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDL-CQSGICTNTDGSFECI 908
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G A +C D+DEC + + P LCG+ C N+ GS
Sbjct: 909 CPPG--HRAGPDLASCLDVDECRE-------------------RGPALCGSQRCENSPGS 947
Query: 414 FVC--QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR--CRDGWRGD 469
+ C C GY PE C D DEC+ + A C N PGS++C C G++
Sbjct: 948 YRCVRDCDPGYHAGPEG--TCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT 1005
Query: 470 -GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
G C+DVDEC N C A C N GSF+CLCD GY+G G CVD++E
Sbjct: 1006 PGGGCQDVDEC-RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRH-------CVDVNE 1057
Query: 529 CANDPTLCENGHCSNTPGGYECDC 552
C +C C N G + C C
Sbjct: 1058 CETLQGVCGAALCENVEGSFLCVC 1081
Score = 206 bits (504), Expect = 1e-52
Identities = 118/312 (37%), Positives = 149/312 (47%), Gaps = 34/312 (10%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDS-KNHTCVDVNECEIVDGVCGDGD 175
+V+EC++ CG HG C N G F C C PGY S + C DVNEC D G+
Sbjct: 797 DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGE 856
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C NT+GSF C C PGY+ C+D+DEC++ D LC+ G C NT GSF C C G
Sbjct: 857 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED-LCQSGICTNTDGSFECICPPGHRA 915
Query: 236 APDRLSCKDIDECSITS-GICSNGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXX 292
PD SC D+DEC +C + CEN G+Y+CV CD GY +
Sbjct: 916 GPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEY 975
Query: 293 XXXRC-QHSCVNTPGSYHCT--CREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVG 348
C C NTPGSY CT C G+ G C+D+DEC + CG C+N G
Sbjct: 976 GPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSF-CGAHAVCQNLPG 1033
Query: 349 SYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCH 408
S+ C C G + G C D++EC L +CGA C
Sbjct: 1034 SFQCLCDQGYEGARDGRH--CVDVNECETLQG--------------------VCGAALCE 1071
Query: 409 NTIGSFVCQCPD 420
N GSF+C CP+
Sbjct: 1072 NVEGSFLCVCPN 1083
Score = 125 bits (302), Expect = 4e-28
Identities = 65/161 (40%), Positives = 82/161 (50%), Gaps = 8/161 (4%)
Query: 117 MEVNECAAF-PGLCGHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNEC-EIVDGVCG 172
++V+EC P LCG RC N G + C DC PGY + TC DV+EC E +CG
Sbjct: 923 LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICG 981
Query: 173 DGDCHNTEGSFTCH--CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECG 230
C NT GS+ C C PGY+ C D+DEC + C N GSF+C C
Sbjct: 982 AQRCENTPGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCLCD 1040
Query: 231 HGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVC 271
G E A D C D++EC G+C CEN G++ CVC
Sbjct: 1041 QGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC 1081
Score = 100 bits (240), Expect = 1e-20
Identities = 54/142 (38%), Positives = 68/142 (47%), Gaps = 14/142 (9%)
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNN 483
PE GP+ C+ C P CI+ P + C C G+R G C DVDEC
Sbjct: 503 PESGPS---SGMCQRNPQVCGPGR-CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVP 558
Query: 484 GGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSN 543
C P C N+ GSFRC+C G++ G R C+D+DEC P C+ G C N
Sbjct: 559 PPCAP-GRCENSPGSFRCVCGPGFRA---GPRAA----ECLDVDECHRVPPPCDLGRCEN 610
Query: 544 TPGGYECDCDVGFTRAADGRSC 565
TPG + C C G+ A G SC
Sbjct: 611 TPGSFLCVCPAGYQAAPHGASC 632
Score = 85.8 bits (203), Expect = 4e-16
Identities = 43/120 (35%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Query: 118 EVNECAAF-PGLCGHGRCRNLLGGFTCD--CFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+V+EC + P +CG RC N G + C C PGY+ + C DV+EC
Sbjct: 968 DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQP-TPGGGCQDVDECRNRSFCGAHA 1026
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C N GSF C C GY+ + CVD++EC +C C N GSF C C + E
Sbjct: 1027 VCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 1086
Score = 85.4 bits (202), Expect = 5e-16
Identities = 42/113 (37%), Positives = 58/113 (51%), Gaps = 5/113 (4%)
Query: 160 DVNECEIV-DGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC 218
DV+EC++ D VC G C NT ++C+C GY C+D DECAD + C GGRC
Sbjct: 1216 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1275
Query: 219 VNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVC 271
VNT GS+ C C + L + C + S+ + G C ++G VC
Sbjct: 1276 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL---GVCWQEVGA-DLVC 1324
Score = 79.0 bits (186), Expect = 4e-14
Identities = 35/79 (44%), Positives = 44/79 (55%), Gaps = 4/79 (5%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC---EIVDGVCG 172
++E EC G C + RC + GFTC CF GY D CVD+NEC E +C
Sbjct: 1494 ELEAEECGILDG-CTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1552
Query: 173 DGDCHNTEGSFTCHCRPGY 191
+ C NT+GSF C CRPG+
Sbjct: 1553 NARCLNTDGSFRCICRPGF 1571
Score = 72.9 bits (171), Expect = 3e-12
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 202 DIDECA-DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGAC 260
D+DEC D +C+ G CVNTA + C C +G RL C D DEC+ C G C
Sbjct: 1216 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1275
Query: 261 ENQMGTYQCVCD 272
N +G+Y C C+
Sbjct: 1276 VNTVGSYHCTCE 1287
Score = 70.5 bits (165), Expect = 1e-11
Identities = 34/77 (44%), Positives = 43/77 (55%), Gaps = 4/77 (5%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDA---LCRG 215
++ EC I+DG C + C FTC C GY+ D CVDI+EC + +A LC
Sbjct: 1495 LEAEECGILDG-CTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 216 GRCVNTAGSFRCECGHG 232
RC+NT GSFRC C G
Sbjct: 1554 ARCLNTDGSFRCICRPG 1570
Score = 66.9 bits (156), Expect = 2e-10
Identities = 29/59 (49%), Positives = 32/59 (54%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
CVNT Y C C G++ C D DECA C GG+C NTVGSY CTC LV
Sbjct: 1233 CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLV 1291
Score = 66.5 bits (155), Expect = 2e-10
Identities = 40/119 (33%), Positives = 50/119 (42%), Gaps = 6/119 (5%)
Query: 213 CRGGRCVNT-AGSFRCECGHGME-LAP--DRLSCKDIDECSI-TSGICSNGACENQMGTY 267
CR +C T ++ C HG LAP D +D+DEC + +C +G C N Y
Sbjct: 1181 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 1240
Query: 268 QCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSC 325
C C GY T + C+ CVNT GSYHCTC L R C
Sbjct: 1241 SCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1299
Score = 64.9 bits (151), Expect = 7e-10
Identities = 37/115 (32%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 118 EVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC F +C G C N G++C C GY ++ C+D +EC + C G C
Sbjct: 1216 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1275
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
NT GS+ C C P D + CV + + +D L G C G+ C H
Sbjct: 1276 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL---GVCWQEVGA-DLVCSH 1326
Score = 64.5 bits (150), Expect = 1e-09
Identities = 33/99 (33%), Positives = 42/99 (42%), Gaps = 7/99 (7%)
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
GD + DVDEC C NT + C C GY Y + + C+D D
Sbjct: 1209 GDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY---YHTQRL----ECIDND 1261
Query: 528 ECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
ECA++ CE G C NT G Y C C+ R C+
Sbjct: 1262 ECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 1300
Score = 62.1 bits (144), Expect = 5e-09
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 201 VDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC---SITSGICSN 257
++ +EC D C RCV F C C G L R++C DI+EC S +C N
Sbjct: 1495 LEAEECGILDG-CTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 258 GACENQMGTYQCVCDEGYAQSTVKSH 283
C N G+++C+C G+A + H
Sbjct: 1554 ARCLNTDGSFRCICRPGFAPTHQPHH 1579
Score = 56.4 bits (130), Expect = 3e-07
Identities = 29/73 (39%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA--TCEDVDECLTNNGGCH--PRATCAN 494
E G D C+ +P F CRC DG+R D C D++EC A C N
Sbjct: 1499 ECGILDGCTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLN 1558
Query: 495 TDGSFRCLCDTGY 507
TDGSFRC+C G+
Sbjct: 1559 TDGSFRCICRPGF 1571
Score = 54.0 bits (124), Expect = 1e-06
Identities = 25/48 (52%), Positives = 30/48 (62%), Gaps = 3/48 (6%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C G+ R +G SC D+DECA G R C G+C NT G YTC C DG +
Sbjct: 307 CPTGFE-RVNG-SCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFL 351
Score = 53.6 bits (123), Expect = 2e-06
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDEC--AGGARP-CGGGQCRNTVGSYTCTCTDG 357
CV P + C C +G+ L +C DI+EC A A P C +C NT GS+ C C G
Sbjct: 1511 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1570
Query: 358 LVPS 361
P+
Sbjct: 1571 FAPT 1574
Score = 52.8 bits (121), Expect = 3e-06
Identities = 19/47 (40%), Positives = 32/47 (68%), Gaps = 1/47 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIA 50
G CS P+ ++ + +CCCS +GKAWG + C+ CP G++ ++ +C A
Sbjct: 379 GGCSLPILRNITKQICCCSRVGKAWG-RGCQLCPPFGSEGFREICPA 424
Score = 50.8 bits (116), Expect = 1e-05
Identities = 21/47 (44%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 522 SCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
SC D+DECA C++G C+NT GGY C C GF + SC+ +
Sbjct: 317 SCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQ 362
Score = 50.4 bits (115), Expect = 2e-05
Identities = 34/121 (28%), Positives = 43/121 (35%), Gaps = 6/121 (4%)
Query: 402 CGAGSCHNT-IGSFVCQCPDGYSVKPEQGPACT--DDDECELGTCDCHPAADCINLPGSF 458
C C T + CP G G D DEC+L + C+N +
Sbjct: 1181 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 1240
Query: 459 QCRCRDG--WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
C C +G + C D DEC C C NT GS+ C C+ DG R
Sbjct: 1241 SCYCSNGYYYHTQRLECIDNDECADEEPACE-GGRCVNTVGSYHCTCEPPLVLDGSQRRC 1299
Query: 517 V 517
V
Sbjct: 1300 V 1300
Score = 49.2 bits (112), Expect = 4e-05
Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS 282
SC+D+DEC+ T G C +G C N G Y CVC +G+ + +S
Sbjct: 317 SCEDVDECA-TGGRCQHGECANTRGGYTCVCPDGFLLDSSRS 357
Score = 48.4 bits (110), Expect = 7e-05
Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 5/63 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC----GD 173
+V+ECA G C HG C N GG+TC C G+ DS +C+ + G C D
Sbjct: 320 DVDECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRD 378
Query: 174 GDC 176
G C
Sbjct: 379 GGC 381
Score = 48.0 bits (109), Expect = 9e-05
Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICV 201
C G+E+ N +C DV+EC G C G+C NT G +TC C G+ D C+
Sbjct: 307 CPTGFER--VNGSCEDVDECA-TGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI 360
Score = 47.6 bits (108), Expect = 1e-04
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 6/85 (7%)
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCH 446
VDE Q D ++C +G C NT + C C +GY Q C D+DEC C
Sbjct: 1217 VDECQLFRD----QVCKSGVCVNTAPGYSCYCSNGYYYH-TQRLECIDNDECADEEPACE 1271
Query: 447 PAADCINLPGSFQCRCRDGWRGDGA 471
C+N GS+ C C DG+
Sbjct: 1272 -GGRCVNTVGSYHCTCEPPLVLDGS 1295
Score = 46.4 bits (105), Expect = 3e-04
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 14/95 (14%)
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC----A 530
+ +EC +G + R C F C C GY+ D + +CVDI+EC A
Sbjct: 1496 EAEECGILDGCTNDR--CVRVPEGFTCRCFDGYRLDMTRM-------ACVDINECDEAEA 1546
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
P LC N C NT G + C C GF C
Sbjct: 1547 ASP-LCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 3/69 (4%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C G++ + S C D+DECA C+ G C NT G + C C G L R SC
Sbjct: 307 CPTGFERVNGS--CEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 363
Query: 247 ECSITSGIC 255
S G C
Sbjct: 364 VISEAKGPC 372
Score = 46.0 bits (104), Expect = 4e-04
Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 462 CRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
C G+ +CEDVDEC T GG CANT G + C+C G+
Sbjct: 307 CPTGFERVNGSCEDVDECAT--GGRCQHGECANTRGGYTCVCPDGF 350
Score = 44.0 bits (99), Expect = 0.001
Identities = 37/131 (28%), Positives = 52/131 (39%), Gaps = 26/131 (19%)
Query: 326 RDIDECA-GGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIM 384
RD+DEC + C G C NT Y+C C++G + C D DECAD
Sbjct: 1215 RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHT--QRLECIDNDECAD------- 1265
Query: 385 MSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC---ELG 441
+P C G C NT+GS+ C C + Q +++ + LG
Sbjct: 1266 ---------EEP----ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLG 1312
Query: 442 TCDCHPAADCI 452
C AD +
Sbjct: 1313 VCWQEVGADLV 1323
Score = 42.7 bits (96), Expect = 0.003
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC---ELGTCDCHPAADCINLPGSF 458
C C F C+C DGY + + AC D +EC E + C A C+N GSF
Sbjct: 1506 CTNDRCVRVPEGFTCRCFDGYRLDMTR-MACVDINECDEAEAASPLC-VNARCLNTDGSF 1563
Query: 459 QCRCRDGW 466
+C CR G+
Sbjct: 1564 RCICRPGF 1571
Score = 37.9 bits (84), Expect = 0.095
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 5/46 (10%)
Query: 117 MEVNEC----AAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC 158
+++NEC AA P LC + RC N G F C C PG+ + H C
Sbjct: 1536 VDINECDEAEAASP-LCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 37.1 bits (82), Expect = 0.17
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 1 MTGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKK 39
+ GG C+ PLP + VCC A G AWG C+ C ++
Sbjct: 256 LRGGECASPLPGLRTQEVCCRGA-GLAWGVHDCQLCSER 293
Score = 37.1 bits (82), Expect = 0.17
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC 338
RCQH C NT G Y C C +G+ L + SC + PC
Sbjct: 329 RCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 372
Score = 36.3 bits (80), Expect = 0.29
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 2/44 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQ-RCEPCPKKGTDAYQNLC 48
C L +V CCC+ +G+ WG+ R + CP T YQ+LC
Sbjct: 1156 CDNILARNVTWQECCCT-VGEGWGSGCRIQQCPGTETAEYQSLC 1198
Score = 34.3 bits (75), Expect = 1.2
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Query: 6 CSGP-LPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPP 57
CS P L CCC G+AWG C CP + +D ++ LC L PP
Sbjct: 1324 CSHPRLDRQATYTECCC-LYGEAWG-MDCALCPAQDSDDFEALC---NVLRPP 1371
Score = 33.5 bits (73), Expect = 2.0
Identities = 18/54 (33%), Positives = 24/54 (44%), Gaps = 5/54 (9%)
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
CP G+ +C D DEC G H +C N G + C C DG+ D +
Sbjct: 307 CPTGFE---RVNGSCEDVDECATGGRCQH--GECANTRGGYTCVCPDGFLLDSS 355
Score = 33.5 bits (73), Expect = 2.0
Identities = 11/21 (52%), Positives = 13/21 (61%)
Query: 402 CGAGSCHNTIGSFVCQCPDGY 422
C G C NT G + C CPDG+
Sbjct: 330 CQHGECANTRGGYTCVCPDGF 350
>M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.
Length = 1394
Score = 334 bits (821), Expect = 5e-91
Identities = 181/452 (40%), Positives = 225/452 (49%), Gaps = 42/452 (9%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
E+NEC P +CG G C NL +TC C+ GY + CVD++EC V +C G C
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCE-CGHGMELA 236
NTEGSF C C G+ A + C+D+DEC D +C G CVNT G+FRCE C G +
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHCVNTVGAFRCEYCDSGYRMT 664
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCV-CDEGYAQSTVKSHXXXXXXXXXXXX 295
R C+DIDEC + C + C N G+YQCV C EG+
Sbjct: 665 -QRGRCEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGF--RGWNGQCLDVDECLEPNV 720
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
C N GSY C+C +G+ D + CRDIDEC G C GQC+NT GS+ CTC
Sbjct: 721 CANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCTCG 779
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G SA AK C+DIDEC Q LC G C NT GSF
Sbjct: 780 QGYQLSA--AKDQCEDIDEC---------------------QHRHLCAHGQCRNTEGSFQ 816
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDGATCE 474
C C GY G C D +EC C DCIN GS+ C C DG++ D TC+
Sbjct: 817 CVCDQGYRAS-GLGDHCEDINECLEDKSVCQ-RGDCINTAGSYDCTCPDGFQLDDNKTCQ 874
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D++EC + G C P+ C NT+GSF C+C G+ G RT C DIDEC N+
Sbjct: 875 DINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADG-RT------CEDIDECVNNTV 926
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+G C NT G + C C GF DG+ C+
Sbjct: 927 CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV 958
Score = 305 bits (749), Expect = 3e-82
Identities = 168/442 (38%), Positives = 220/442 (49%), Gaps = 48/442 (10%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC LC GRC N G F C C G+ + C+DV+EC D VCG+G C
Sbjct: 587 VDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHC 645
Query: 177 HNTEGSFTC-HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC-ECGHGME 234
NT G+F C +C GY+ + C DIDEC N + C +CVN+ GS++C C G
Sbjct: 646 VNTVGAFRCEYCDSGYRMTQRGR-CEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGFR 703
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ C D+DEC + +C+NG C N G+Y C C +GY ++ H
Sbjct: 704 GWNGQ--CLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN 760
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C NT GS+ CTC +G+ L A C DIDEC C GQCRNT GS+ C C
Sbjct: 761 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVC 819
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G A+G C+DI+EC + KSV C G C NT GS+
Sbjct: 820 DQGY--RASGLGDHCEDINECLE-------------DKSV-------CQRGDCINTAGSY 857
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C CPDG+ + + C D +ECE C P +C+N GSF C C+ G+ DG T
Sbjct: 858 DCTCPDGFQL--DDNKTCQDINECEHPGL-CGPQGECLNTEGSFHCVCQQGFSISADGRT 914
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG--DGYGLRTVCCVYSCVDIDECA 530
CED+DEC+ NN C C NT GSFRCLC G++ DG G CVD++EC
Sbjct: 915 CEDIDECV-NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQG---------CVDVNECE 964
Query: 531 NDPTLCENGHCSNTPGGYECDC 552
+C C N G + C C
Sbjct: 965 LLSGVCGEAFCENVEGSFLCVC 986
Score = 250 bits (611), Expect = 1e-65
Identities = 141/351 (40%), Positives = 184/351 (52%), Gaps = 37/351 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTC-DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++EC P C +C N G + C C G+ N C+DV+EC + VC +GDC
Sbjct: 671 DIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR--GWNGQCLDVDEC-LEPNVCANGDC 726
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N EGS+ C C GY K C DIDEC + LC G+C NT GSFRC CG G +L+
Sbjct: 727 SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN-LCVNGQCKNTEGSFRCTCGQGYQLS 785
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+ C+DIDEC +C++G C N G++QCVCD+GY S + H
Sbjct: 786 AAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV 844
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTC 354
CQ C+NT GSY CTC +G+ L D ++C+DI+EC CG G+C NT GS+ C C
Sbjct: 845 CQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPGL-CGPQGECLNTEGSFHCVC 902
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGS 413
G SA G TC+DIDEC + +T+ C + G C NT GS
Sbjct: 903 QQGFSISADGR--TCEDIDECVN--NTV-------------------CDSHGFCDNTAGS 939
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
F C C G+ P+ G C D +ECEL + C A C N+ GSF C C D
Sbjct: 940 FRCLCYQGFQA-PQDGQGCVDVNECELLSGVCGEAF-CENVEGSFLCVCAD 988
Score = 230 bits (562), Expect = 1e-59
Identities = 142/458 (31%), Positives = 200/458 (43%), Gaps = 38/458 (8%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC LC +G+C+N G F C C GY+ + C D++EC+ +C G C
Sbjct: 752 DIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH-LCAHGQCR 809
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NTEGSF C C GY+A C DI+EC ++ ++C+ G C+NTAGS+ C C G +L
Sbjct: 810 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-D 868
Query: 238 DRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
D +C+DI+EC G+C G C N G++ CVC +G++ S
Sbjct: 869 DNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 927
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
H C NT GS+ C C +G+ DG+ C D++EC + CG C N GS+ C C
Sbjct: 928 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCA 987
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
D + + T Q C ST + + VD+ ++ L A C N + V
Sbjct: 988 D---ENQEYSPMTGQ----CRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNV 1040
Query: 416 ----CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINL---PGSFQCRCRDGWRG 468
C C G D CE+ C A+ + F
Sbjct: 1041 TKQECCCTSGAGW----------GDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEA 1090
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
G +D DECL C NT + C C G D L+ C D+DE
Sbjct: 1091 GGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQ-------CFDMDE 1143
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DP+ C +G C NT G Y C C A + C+
Sbjct: 1144 C-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI 1180
Score = 83.0 bits (196), Expect = 3e-15
Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVD---GVCG 172
+++ EC G C +GRC + G+TCDC GY D+ TC DVNEC+ ++ +C
Sbjct: 1292 ELQAEECGILNG-CENGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCK 1350
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
+ C NT+GS+ C C PGY D C ++
Sbjct: 1351 NAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1382
Score = 64.5 bits (150), Expect = 1e-09
Identities = 69/276 (25%), Positives = 100/276 (36%), Gaps = 32/276 (11%)
Query: 118 EVNECAAF-PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECE----IVDGVC- 171
+ +EC F +C +G C N G+ C C G D C D++EC+ +DG C
Sbjct: 1097 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCV 1156
Query: 172 ---GDGDCHNT-----EGSFTCHCRPGYKADDFSKICVDIDECADN---DALCRGGRCVN 220
G +C T + S RP + + V D C ++ + +C
Sbjct: 1157 NTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGK 1216
Query: 221 TAGSFRCECGHGMELAPDRLSC--KDIDECSITSGICSNG--------ACENQMGTYQCV 270
C C +G C KD D+ + I G A + Y
Sbjct: 1217 QTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPE 1276
Query: 271 CDEGYAQST-VKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDI 328
D + Q + S C++ CV Y C C +G+HL +C D+
Sbjct: 1277 ADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKMTCFDV 1336
Query: 329 DEC---AGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
+EC C +C NT GSY C C G VPS
Sbjct: 1337 NECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS 1372
Score = 59.7 bits (138), Expect = 3e-08
Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICV 201
+C PGY++ + N C D+NEC++ GVC +G+C NT GS+ C C+ G+ D CV
Sbjct: 285 ECLPGYKRVN-NTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Score = 56.0 bits (129), Expect = 3e-07
Identities = 27/61 (44%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 451 CINLPGSFQCRCRDGWRGDGA--TCEDVDEC--LTNNGGCHPRATCANTDGSFRCLCDTG 506
C+ + + C C DG+ D A TC DV+EC L N A C NTDGS++CLC G
Sbjct: 1309 CVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1368
Query: 507 Y 507
Y
Sbjct: 1369 Y 1369
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/56 (42%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC 242
C PGYK + + C DI+EC +C G C+NT GS+RC C G P SC
Sbjct: 286 CLPGYKRVN-NTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/34 (50%), Positives = 24/34 (70%), Gaps = 1/34 (2%)
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+DI+EC + G+C NG C N MG+Y+C C G+
Sbjct: 298 CQDINECQL-QGVCPNGECLNTMGSYRCTCKIGF 330
Score = 46.8 bits (106), Expect = 2e-04
Identities = 36/105 (34%), Positives = 44/105 (41%), Gaps = 21/105 (20%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
+EC G C G+C YTC C DG A K TC D++EC D
Sbjct: 1296 EEC-GILNGCENGRCVRVQEGYTCDCLDGYHLDTA--KMTCFDVNEC------------D 1340
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
EL + LC C NT GS+ C C GY V ++ CT
Sbjct: 1341 ELNNRMS-----LCKNAKCINTDGSYKCLCLPGY-VPSDKPNYCT 1379
Score = 46.0 bits (104), Expect = 4e-04
Identities = 28/70 (40%), Positives = 35/70 (50%), Gaps = 9/70 (12%)
Query: 296 RCQHSCVNTPGSYH-----CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSY 350
+CQ C P SYH C G+ R + C+DI+EC C G+C NT+GSY
Sbjct: 267 KCQ-KCPKKP-SYHGYNQMMECLPGYK-RVNNTFCQDINECQLQG-VCPNGECLNTMGSY 322
Query: 351 TCTCTDGLVP 360
CTC G P
Sbjct: 323 RCTCKIGFGP 332
Score = 44.8 bits (101), Expect = 8e-04
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 12/92 (13%)
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA---NDP 533
+EC NG C C + C C DGY L T +C D++EC N
Sbjct: 1296 EECGILNG-CE-NGRCVRVQEGYTCDCL-----DGYHLDTA--KMTCFDVNECDELNNRM 1346
Query: 534 TLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+LC+N C NT G Y+C C G+ + C
Sbjct: 1347 SLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1378
Score = 43.6 bits (98), Expect = 0.002
Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DI+EC +C NG C NT G Y C C +GF SC+
Sbjct: 298 CQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Score = 43.6 bits (98), Expect = 0.002
Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
+G +C PL + + +CCCS +GKA CE CP GT A++ +C
Sbjct: 359 SGRQCMYPLSVHLTKQLCCCS-VGKA--GPHCEKCPLPGTAAFKEIC 402
Score = 43.6 bits (98), Expect = 0.002
Identities = 71/288 (24%), Positives = 99/288 (34%), Gaps = 38/288 (13%)
Query: 202 DIDECA-DNDALCRGGRCVNTAGSFRCECGHGMELAP------DRLSCKD----ID-ECS 249
D DEC +C+ G C+NT + C C G P D C+D ID +C
Sbjct: 1097 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCV 1156
Query: 250 ITSGICSNGACENQM----GTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVN 303
T G N C + M +C+ + + C V
Sbjct: 1157 NTEG-SYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVG 1215
Query: 304 TPGSY-HCTCR--EGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP 360
+Y C C E W ++ +D D+ A G+ R G D LV
Sbjct: 1216 KQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGR-RQPYGR------DALVD 1268
Query: 361 SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD 420
+ P I + S +ELQ + I C G C + C C D
Sbjct: 1269 FSEQYTPEADPY-----FIQDRFLNSFEELQAE-ECGILNGCENGRCVRVQEGYTCDCLD 1322
Query: 421 GYSVKPEQGPACTDDDEC-ELGT-CDCHPAADCINLPGSFQCRCRDGW 466
GY + + C D +EC EL A CIN GS++C C G+
Sbjct: 1323 GYHLDTAK-MTCFDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1369
Score = 41.1 bits (92), Expect = 0.010
Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
Query: 462 CRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
C G+ R + C+D++EC G C P C NT GS+RC C G+ D
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQ-GVC-PNGECLNTMGSYRCTCKIGFGPD 333
Score = 39.9 bits (89), Expect = 0.024
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
CS PL CC G+AWG Q C CP K +D Y LC
Sbjct: 1209 CSRPLVGKQTTYTECCCLYGEAWGMQ-CALCPLKDSDDYAQLC 1250
Score = 38.7 bits (86), Expect = 0.054
Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
Query: 417 QCPDGYSVKPEQGPACTDDDECEL-GTCDCHPAADCINLPGSFQCRCRDGWRGD 469
+C GY K C D +EC+L G C P +C+N GS++C C+ G+ D
Sbjct: 285 ECLPGY--KRVNNTFCQDINECQLQGVC---PNGECLNTMGSYRCTCKIGFGPD 333
Score = 38.7 bits (86), Expect = 0.054
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV 159
++NEC G+C +G C N +G + C C G+ D +CV
Sbjct: 300 DINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Score = 37.9 bits (84), Expect = 0.095
Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKK 39
G +C LP + + CC +G +WG +C+ CPKK
Sbjct: 239 GSQCGKALP-GLSKQEDCCGTVGTSWGFNKCQKCPKK 274
Score = 37.5 bits (83), Expect = 0.13
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCE--PCPKKGTDAYQNLC 48
C L +V + CCC++ G WG+ CE PCP GT + +C
Sbjct: 1032 CDNVLAPNVTKQECCCTS-GAGWGD-NCEIFPCPVLGTAEFTEMC 1074
Score = 32.3 bits (70), Expect = 4.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 397 QIPELCGAGSCHNTIGSFVCQCPDGYSVKP 426
Q+ +C G C NT+GS+ C C G+ P
Sbjct: 305 QLQGVCPNGECLNTMGSYRCTCKIGFGPDP 334
>BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming growth
factor beta binding protein 1 protein.
Length = 1395
Score = 334 bits (821), Expect = 5e-91
Identities = 181/452 (40%), Positives = 225/452 (49%), Gaps = 42/452 (9%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
E+NEC P +CG G C NL +TC C+ GY + CVD++EC V +C G C
Sbjct: 547 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 606
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCE-CGHGMELA 236
NTEGSF C C G+ A + C+D+DEC D +C G CVNT G+FRCE C G +
Sbjct: 607 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHCVNTVGAFRCEYCDSGYRMT 665
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCV-CDEGYAQSTVKSHXXXXXXXXXXXX 295
R C+DIDEC + C + C N G+YQCV C EG+
Sbjct: 666 -QRGRCEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGF--RGWNGQCLDVDECLEPNV 721
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
C N GSY C+C +G+ D + CRDIDEC G C GQC+NT GS+ CTC
Sbjct: 722 CANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCTCG 780
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G SA AK C+DIDEC Q LC G C NT GSF
Sbjct: 781 QGYQLSA--AKDQCEDIDEC---------------------QHRHLCAHGQCRNTEGSFQ 817
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDGATCE 474
C C GY G C D +EC C DCIN GS+ C C DG++ D TC+
Sbjct: 818 CVCDQGYRAS-GLGDHCEDINECLEDKSVCQ-RGDCINTAGSYDCTCPDGFQLDDNKTCQ 875
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D++EC + G C P+ C NT+GSF C+C G+ G RT C DIDEC N+
Sbjct: 876 DINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADG-RT------CEDIDECVNNTV 927
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+G C NT G + C C GF DG+ C+
Sbjct: 928 CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV 959
Score = 305 bits (749), Expect = 3e-82
Identities = 168/442 (38%), Positives = 220/442 (49%), Gaps = 48/442 (10%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC LC GRC N G F C C G+ + C+DV+EC D VCG+G C
Sbjct: 588 VDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHC 646
Query: 177 HNTEGSFTC-HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC-ECGHGME 234
NT G+F C +C GY+ + C DIDEC N + C +CVN+ GS++C C G
Sbjct: 647 VNTVGAFRCEYCDSGYRMTQRGR-CEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGFR 704
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ C D+DEC + +C+NG C N G+Y C C +GY ++ H
Sbjct: 705 GWNGQ--CLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN 761
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C NT GS+ CTC +G+ L A C DIDEC C GQCRNT GS+ C C
Sbjct: 762 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVC 820
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G A+G C+DI+EC + KSV C G C NT GS+
Sbjct: 821 DQGY--RASGLGDHCEDINECLE-------------DKSV-------CQRGDCINTAGSY 858
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C CPDG+ + + C D +ECE C P +C+N GSF C C+ G+ DG T
Sbjct: 859 DCTCPDGFQL--DDNKTCQDINECEHPGL-CGPQGECLNTEGSFHCVCQQGFSISADGRT 915
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG--DGYGLRTVCCVYSCVDIDECA 530
CED+DEC+ NN C C NT GSFRCLC G++ DG G CVD++EC
Sbjct: 916 CEDIDECV-NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQG---------CVDVNECE 965
Query: 531 NDPTLCENGHCSNTPGGYECDC 552
+C C N G + C C
Sbjct: 966 LLSGVCGEAFCENVEGSFLCVC 987
Score = 250 bits (611), Expect = 1e-65
Identities = 141/351 (40%), Positives = 184/351 (52%), Gaps = 37/351 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTC-DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++EC P C +C N G + C C G+ N C+DV+EC + VC +GDC
Sbjct: 672 DIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR--GWNGQCLDVDEC-LEPNVCANGDC 727
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N EGS+ C C GY K C DIDEC + LC G+C NT GSFRC CG G +L+
Sbjct: 728 SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN-LCVNGQCKNTEGSFRCTCGQGYQLS 786
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+ C+DIDEC +C++G C N G++QCVCD+GY S + H
Sbjct: 787 AAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV 845
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTC 354
CQ C+NT GSY CTC +G+ L D ++C+DI+EC CG G+C NT GS+ C C
Sbjct: 846 CQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPGL-CGPQGECLNTEGSFHCVC 903
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGS 413
G SA G TC+DIDEC + +T+ C + G C NT GS
Sbjct: 904 QQGFSISADGR--TCEDIDECVN--NTV-------------------CDSHGFCDNTAGS 940
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
F C C G+ P+ G C D +ECEL + C A C N+ GSF C C D
Sbjct: 941 FRCLCYQGFQA-PQDGQGCVDVNECELLSGVCGEAF-CENVEGSFLCVCAD 989
Score = 230 bits (562), Expect = 1e-59
Identities = 142/458 (31%), Positives = 200/458 (43%), Gaps = 38/458 (8%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC LC +G+C+N G F C C GY+ + C D++EC+ +C G C
Sbjct: 753 DIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH-LCAHGQCR 810
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NTEGSF C C GY+A C DI+EC ++ ++C+ G C+NTAGS+ C C G +L
Sbjct: 811 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-D 869
Query: 238 DRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
D +C+DI+EC G+C G C N G++ CVC +G++ S
Sbjct: 870 DNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 928
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
H C NT GS+ C C +G+ DG+ C D++EC + CG C N GS+ C C
Sbjct: 929 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCA 988
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
D + + T Q C ST + + VD+ ++ L A C N + V
Sbjct: 989 D---ENQEYSPMTGQ----CRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNV 1041
Query: 416 ----CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINL---PGSFQCRCRDGWRG 468
C C G D CE+ C A+ + F
Sbjct: 1042 TKQECCCTSGAGW----------GDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEA 1091
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
G +D DECL C NT + C C G D L+ C D+DE
Sbjct: 1092 GGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQ-------CFDMDE 1144
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DP+ C +G C NT G Y C C A + C+
Sbjct: 1145 C-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI 1181
Score = 87.4 bits (207), Expect = 1e-16
Identities = 37/92 (40%), Positives = 53/92 (57%), Gaps = 4/92 (4%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVD---GVCG 172
+++ EC G C +GRC + G+TCDCF GY D+ TCVDVNEC+ ++ +C
Sbjct: 1293 ELQAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCK 1351
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
+ C NT+GS+ C C PGY D C ++
Sbjct: 1352 NAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1383
Score = 66.1 bits (154), Expect = 3e-10
Identities = 27/74 (36%), Positives = 43/74 (58%), Gaps = 4/74 (5%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADND---ALCRG 215
+ EC I++G C +G C + +TC C GY D CVD++EC + + +LC+
Sbjct: 1294 LQAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN 1352
Query: 216 GRCVNTAGSFRCEC 229
+C+NT GS++C C
Sbjct: 1353 AKCINTDGSYKCLC 1366
Score = 64.1 bits (149), Expect = 1e-09
Identities = 69/276 (25%), Positives = 100/276 (36%), Gaps = 32/276 (11%)
Query: 118 EVNECAAF-PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECE----IVDGVC- 171
+ +EC F +C +G C N G+ C C G D C D++EC+ +DG C
Sbjct: 1098 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCV 1157
Query: 172 ---GDGDCHNT-----EGSFTCHCRPGYKADDFSKICVDIDECADN---DALCRGGRCVN 220
G +C T + S RP + + V D C ++ + +C
Sbjct: 1158 NTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGK 1217
Query: 221 TAGSFRCECGHGMELAPDRLSC--KDIDECSITSGICSNG--------ACENQMGTYQCV 270
C C +G C KD D+ + I G A + Y
Sbjct: 1218 QTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPE 1277
Query: 271 CDEGYAQST-VKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDI 328
D + Q + S C++ CV Y C C +G+HL +C D+
Sbjct: 1278 ADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDV 1337
Query: 329 DEC---AGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
+EC C +C NT GSY C C G VPS
Sbjct: 1338 NECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS 1373
Score = 59.7 bits (138), Expect = 3e-08
Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICV 201
+C PGY++ + N C D+NEC++ GVC +G+C NT GS+ C C+ G+ D CV
Sbjct: 285 ECLPGYKRVN-NTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Score = 56.0 bits (129), Expect = 3e-07
Identities = 27/61 (44%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 451 CINLPGSFQCRCRDGWRGDGA--TCEDVDEC--LTNNGGCHPRATCANTDGSFRCLCDTG 506
C+ + + C C DG+ D A TC DV+EC L N A C NTDGS++CLC G
Sbjct: 1310 CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1369
Query: 507 Y 507
Y
Sbjct: 1370 Y 1370
Score = 51.6 bits (118), Expect = 7e-06
Identities = 21/47 (44%), Positives = 30/47 (63%), Gaps = 2/47 (4%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
+G +C PL + + +CCCS +GKAWG CE CP GT A++ +C
Sbjct: 359 SGRQCMHPLSVHLTKQLCCCS-VGKAWG-PHCEKCPLPGTAAFKEIC 403
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/56 (42%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC 242
C PGYK + + C DI+EC +C G C+NT GS+RC C G P SC
Sbjct: 286 CLPGYKRVN-NTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/34 (50%), Positives = 24/34 (70%), Gaps = 1/34 (2%)
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+DI+EC + G+C NG C N MG+Y+C C G+
Sbjct: 298 CQDINECQL-QGVCPNGECLNTMGSYRCTCKIGF 330
Score = 47.2 bits (107), Expect = 2e-04
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 12/92 (13%)
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA---NDP 533
+EC NG C C + C C DGY L T +CVD++EC N
Sbjct: 1297 EECGILNG-CE-NGRCVRVQEGYTCDCF-----DGYHLDTA--KMTCVDVNECDELNNRM 1347
Query: 534 TLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+LC+N C NT G Y+C C G+ + C
Sbjct: 1348 SLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1379
Score = 46.8 bits (106), Expect = 2e-04
Identities = 36/105 (34%), Positives = 44/105 (41%), Gaps = 21/105 (20%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
+EC G C G+C YTC C DG A K TC D++EC D
Sbjct: 1297 EEC-GILNGCENGRCVRVQEGYTCDCFDGYHLDTA--KMTCVDVNEC------------D 1341
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
EL + LC C NT GS+ C C GY V ++ CT
Sbjct: 1342 ELNNRMS-----LCKNAKCINTDGSYKCLCLPGY-VPSDKPNYCT 1380
Score = 46.0 bits (104), Expect = 4e-04
Identities = 28/70 (40%), Positives = 35/70 (50%), Gaps = 9/70 (12%)
Query: 296 RCQHSCVNTPGSYH-----CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSY 350
+CQ C P SYH C G+ R + C+DI+EC C G+C NT+GSY
Sbjct: 267 KCQ-KCPKKP-SYHGYNQMMECLPGYK-RVNNTFCQDINECQLQG-VCPNGECLNTMGSY 322
Query: 351 TCTCTDGLVP 360
CTC G P
Sbjct: 323 RCTCKIGFGP 332
Score = 44.0 bits (99), Expect = 0.001
Identities = 71/288 (24%), Positives = 99/288 (34%), Gaps = 38/288 (13%)
Query: 202 DIDECA-DNDALCRGGRCVNTAGSFRCECGHGMELAP------DRLSCKD----ID-ECS 249
D DEC +C+ G C+NT + C C G P D C+D ID +C
Sbjct: 1098 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCV 1157
Query: 250 ITSGICSNGACENQM----GTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVN 303
T G N C + M +C+ + + C V
Sbjct: 1158 NTEG-SYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVG 1216
Query: 304 TPGSY-HCTCR--EGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP 360
+Y C C E W ++ +D D+ A G+ R G D LV
Sbjct: 1217 KQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGR-RQPYGR------DALVD 1269
Query: 361 SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD 420
+ P I + S +ELQ + I C G C + C C D
Sbjct: 1270 FSEQYTPEADPY-----FIQDRFLNSFEELQAE-ECGILNGCENGRCVRVQEGYTCDCFD 1323
Query: 421 GYSVKPEQGPACTDDDEC-ELGT-CDCHPAADCINLPGSFQCRCRDGW 466
GY + + C D +EC EL A CIN GS++C C G+
Sbjct: 1324 GYHLDTAK-MTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1370
Score = 43.6 bits (98), Expect = 0.002
Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DI+EC +C NG C NT G Y C C +GF SC+
Sbjct: 298 CQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Score = 41.1 bits (92), Expect = 0.010
Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
Query: 462 CRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
C G+ R + C+D++EC G C P C NT GS+RC C G+ D
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQ-GVC-PNGECLNTMGSYRCTCKIGFGPD 333
Score = 39.9 bits (89), Expect = 0.024
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
CS PL CC G+AWG Q C CP K +D Y LC
Sbjct: 1210 CSRPLVGKQTTYTECCCLYGEAWGMQ-CALCPLKDSDDYAQLC 1251
Score = 38.7 bits (86), Expect = 0.054
Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
Query: 417 QCPDGYSVKPEQGPACTDDDECEL-GTCDCHPAADCINLPGSFQCRCRDGWRGD 469
+C GY K C D +EC+L G C P +C+N GS++C C+ G+ D
Sbjct: 285 ECLPGY--KRVNNTFCQDINECQLQGVC---PNGECLNTMGSYRCTCKIGFGPD 333
Score = 38.7 bits (86), Expect = 0.054
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV 159
++NEC G+C +G C N +G + C C G+ D +CV
Sbjct: 300 DINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Score = 37.9 bits (84), Expect = 0.095
Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKK 39
G +C LP + + CC +G +WG +C+ CPKK
Sbjct: 239 GSQCGKALP-GLSKQEDCCGTVGTSWGFNKCQKCPKK 274
Score = 37.5 bits (83), Expect = 0.13
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCE--PCPKKGTDAYQNLC 48
C L +V + CCC++ G WG+ CE PCP GT + +C
Sbjct: 1033 CDNVLAPNVTKQECCCTS-GAGWGD-NCEIFPCPVLGTAEFTEMC 1075
Score = 32.3 bits (70), Expect = 4.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 397 QIPELCGAGSCHNTIGSFVCQCPDGYSVKP 426
Q+ +C G C NT+GS+ C C G+ P
Sbjct: 305 QLQGVCPNGECLNTMGSYRCTCKIGFGPDP 334
>AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth
factor-beta binding protein-1S protein.
Length = 1394
Score = 334 bits (821), Expect = 5e-91
Identities = 181/452 (40%), Positives = 225/452 (49%), Gaps = 42/452 (9%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
E+NEC P +CG G C NL +TC C+ GY + CVD++EC V +C G C
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCE-CGHGMELA 236
NTEGSF C C G+ A + C+D+DEC D +C G CVNT G+FRCE C G +
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHCVNTVGAFRCEYCDSGYRMT 664
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCV-CDEGYAQSTVKSHXXXXXXXXXXXX 295
R C+DIDEC + C + C N G+YQCV C EG+
Sbjct: 665 -QRGRCEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGF--RGWNGQCLDVDECLEPNV 720
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
C N GSY C+C +G+ D + CRDIDEC G C GQC+NT GS+ CTC
Sbjct: 721 CANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCTCG 779
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G SA AK C+DIDEC Q LC G C NT GSF
Sbjct: 780 QGYQLSA--AKDQCEDIDEC---------------------QHRHLCAHGQCRNTEGSFQ 816
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDGATCE 474
C C GY G C D +EC C DCIN GS+ C C DG++ D TC+
Sbjct: 817 CVCDQGYRAS-GLGDHCEDINECLEDKSVCQ-RGDCINTAGSYDCTCPDGFQLDDNKTCQ 874
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D++EC + G C P+ C NT+GSF C+C G+ G RT C DIDEC N+
Sbjct: 875 DINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADG-RT------CEDIDECVNNTV 926
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+G C NT G + C C GF DG+ C+
Sbjct: 927 CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV 958
Score = 305 bits (749), Expect = 3e-82
Identities = 168/442 (38%), Positives = 220/442 (49%), Gaps = 48/442 (10%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC LC GRC N G F C C G+ + C+DV+EC D VCG+G C
Sbjct: 587 VDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHC 645
Query: 177 HNTEGSFTC-HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC-ECGHGME 234
NT G+F C +C GY+ + C DIDEC N + C +CVN+ GS++C C G
Sbjct: 646 VNTVGAFRCEYCDSGYRMTQRGR-CEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGFR 703
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ C D+DEC + +C+NG C N G+Y C C +GY ++ H
Sbjct: 704 GWNGQ--CLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN 760
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C NT GS+ CTC +G+ L A C DIDEC C GQCRNT GS+ C C
Sbjct: 761 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVC 819
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G A+G C+DI+EC + KSV C G C NT GS+
Sbjct: 820 DQGY--RASGLGDHCEDINECLE-------------DKSV-------CQRGDCINTAGSY 857
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C CPDG+ + + C D +ECE C P +C+N GSF C C+ G+ DG T
Sbjct: 858 DCTCPDGFQL--DDNKTCQDINECEHPGL-CGPQGECLNTEGSFHCVCQQGFSISADGRT 914
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG--DGYGLRTVCCVYSCVDIDECA 530
CED+DEC+ NN C C NT GSFRCLC G++ DG G CVD++EC
Sbjct: 915 CEDIDECV-NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQG---------CVDVNECE 964
Query: 531 NDPTLCENGHCSNTPGGYECDC 552
+C C N G + C C
Sbjct: 965 LLSGVCGEAFCENVEGSFLCVC 986
Score = 250 bits (611), Expect = 1e-65
Identities = 141/351 (40%), Positives = 184/351 (52%), Gaps = 37/351 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTC-DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++EC P C +C N G + C C G+ N C+DV+EC + VC +GDC
Sbjct: 671 DIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR--GWNGQCLDVDEC-LEPNVCANGDC 726
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N EGS+ C C GY K C DIDEC + LC G+C NT GSFRC CG G +L+
Sbjct: 727 SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN-LCVNGQCKNTEGSFRCTCGQGYQLS 785
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+ C+DIDEC +C++G C N G++QCVCD+GY S + H
Sbjct: 786 AAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV 844
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTC 354
CQ C+NT GSY CTC +G+ L D ++C+DI+EC CG G+C NT GS+ C C
Sbjct: 845 CQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPGL-CGPQGECLNTEGSFHCVC 902
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGS 413
G SA G TC+DIDEC + +T+ C + G C NT GS
Sbjct: 903 QQGFSISADGR--TCEDIDECVN--NTV-------------------CDSHGFCDNTAGS 939
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
F C C G+ P+ G C D +ECEL + C A C N+ GSF C C D
Sbjct: 940 FRCLCYQGFQA-PQDGQGCVDVNECELLSGVCGEAF-CENVEGSFLCVCAD 988
Score = 230 bits (562), Expect = 1e-59
Identities = 142/458 (31%), Positives = 200/458 (43%), Gaps = 38/458 (8%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC LC +G+C+N G F C C GY+ + C D++EC+ +C G C
Sbjct: 752 DIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH-LCAHGQCR 809
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NTEGSF C C GY+A C DI+EC ++ ++C+ G C+NTAGS+ C C G +L
Sbjct: 810 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-D 868
Query: 238 DRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
D +C+DI+EC G+C G C N G++ CVC +G++ S
Sbjct: 869 DNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 927
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
H C NT GS+ C C +G+ DG+ C D++EC + CG C N GS+ C C
Sbjct: 928 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCA 987
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
D + + T Q C ST + + VD+ ++ L A C N + V
Sbjct: 988 D---ENQEYSPMTGQ----CRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNV 1040
Query: 416 ----CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINL---PGSFQCRCRDGWRG 468
C C G D CE+ C A+ + F
Sbjct: 1041 TKQECCCTSGAGW----------GDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEA 1090
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
G +D DECL C NT + C C G D L+ C D+DE
Sbjct: 1091 GGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQ-------CFDMDE 1143
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DP+ C +G C NT G Y C C A + C+
Sbjct: 1144 C-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI 1180
Score = 85.0 bits (201), Expect = 6e-16
Identities = 36/92 (39%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVD---GVCG 172
+++ EC G C +GRC + G+TCDC GY D+ TCVDVNEC+ ++ +C
Sbjct: 1292 ELQAEECGILNG-CENGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCK 1350
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
+ C NT+GS+ C C PGY D C ++
Sbjct: 1351 NAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1382
Score = 66.5 bits (155), Expect = 2e-10
Identities = 27/74 (36%), Positives = 43/74 (58%), Gaps = 4/74 (5%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADND---ALCRG 215
+ EC I++G C +G C + +TC C GY D CVD++EC + + +LC+
Sbjct: 1293 LQAEECGILNG-CENGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKN 1351
Query: 216 GRCVNTAGSFRCEC 229
+C+NT GS++C C
Sbjct: 1352 AKCINTDGSYKCLC 1365
Score = 64.5 bits (150), Expect = 1e-09
Identities = 69/276 (25%), Positives = 100/276 (36%), Gaps = 32/276 (11%)
Query: 118 EVNECAAF-PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECE----IVDGVC- 171
+ +EC F +C +G C N G+ C C G D C D++EC+ +DG C
Sbjct: 1097 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCV 1156
Query: 172 ---GDGDCHNT-----EGSFTCHCRPGYKADDFSKICVDIDECADN---DALCRGGRCVN 220
G +C T + S RP + + V D C ++ + +C
Sbjct: 1157 NTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGK 1216
Query: 221 TAGSFRCECGHGMELAPDRLSC--KDIDECSITSGICSNG--------ACENQMGTYQCV 270
C C +G C KD D+ + I G A + Y
Sbjct: 1217 QTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPE 1276
Query: 271 CDEGYAQST-VKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDI 328
D + Q + S C++ CV Y C C +G+HL +C D+
Sbjct: 1277 ADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKMTCVDV 1336
Query: 329 DEC---AGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
+EC C +C NT GSY C C G VPS
Sbjct: 1337 NECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS 1372
Score = 59.7 bits (138), Expect = 3e-08
Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICV 201
+C PGY++ + N C D+NEC++ GVC +G+C NT GS+ C C+ G+ D CV
Sbjct: 285 ECLPGYKRVN-NTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Score = 56.4 bits (130), Expect = 3e-07
Identities = 27/61 (44%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 451 CINLPGSFQCRCRDGWRGDGA--TCEDVDEC--LTNNGGCHPRATCANTDGSFRCLCDTG 506
C+ + + C C DG+ D A TC DV+EC L N A C NTDGS++CLC G
Sbjct: 1309 CVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1368
Query: 507 Y 507
Y
Sbjct: 1369 Y 1369
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/56 (42%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC 242
C PGYK + + C DI+EC +C G C+NT GS+RC C G P SC
Sbjct: 286 CLPGYKRVN-NTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/34 (50%), Positives = 24/34 (70%), Gaps = 1/34 (2%)
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+DI+EC + G+C NG C N MG+Y+C C G+
Sbjct: 298 CQDINECQL-QGVCPNGECLNTMGSYRCTCKIGF 330
Score = 47.2 bits (107), Expect = 2e-04
Identities = 36/105 (34%), Positives = 44/105 (41%), Gaps = 21/105 (20%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
+EC G C G+C YTC C DG A K TC D++EC D
Sbjct: 1296 EEC-GILNGCENGRCVRVQEGYTCDCLDGYHLDTA--KMTCVDVNEC------------D 1340
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
EL + LC C NT GS+ C C GY V ++ CT
Sbjct: 1341 ELNNRMS-----LCKNAKCINTDGSYKCLCLPGY-VPSDKPNYCT 1379
Score = 46.8 bits (106), Expect = 2e-04
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 12/92 (13%)
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA---NDP 533
+EC NG C C + C C DGY L T +CVD++EC N
Sbjct: 1296 EECGILNG-CE-NGRCVRVQEGYTCDCL-----DGYHLDTA--KMTCVDVNECDELNNRM 1346
Query: 534 TLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+LC+N C NT G Y+C C G+ + C
Sbjct: 1347 SLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1378
Score = 46.0 bits (104), Expect = 4e-04
Identities = 28/70 (40%), Positives = 35/70 (50%), Gaps = 9/70 (12%)
Query: 296 RCQHSCVNTPGSYH-----CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSY 350
+CQ C P SYH C G+ R + C+DI+EC C G+C NT+GSY
Sbjct: 267 KCQ-KCPKKP-SYHGYNQMMECLPGYK-RVNNTFCQDINECQLQG-VCPNGECLNTMGSY 322
Query: 351 TCTCTDGLVP 360
CTC G P
Sbjct: 323 RCTCKIGFGP 332
Score = 44.4 bits (100), Expect = 0.001
Identities = 71/288 (24%), Positives = 99/288 (34%), Gaps = 38/288 (13%)
Query: 202 DIDECA-DNDALCRGGRCVNTAGSFRCECGHGMELAP------DRLSCKD----ID-ECS 249
D DEC +C+ G C+NT + C C G P D C+D ID +C
Sbjct: 1097 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCV 1156
Query: 250 ITSGICSNGACENQM----GTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVN 303
T G N C + M +C+ + + C V
Sbjct: 1157 NTEG-SYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVG 1215
Query: 304 TPGSY-HCTCR--EGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP 360
+Y C C E W ++ +D D+ A G+ R G D LV
Sbjct: 1216 KQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGR-RQPYGR------DALVD 1268
Query: 361 SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD 420
+ P I + S +ELQ + I C G C + C C D
Sbjct: 1269 FSEQYTPEADPY-----FIQDRFLNSFEELQAE-ECGILNGCENGRCVRVQEGYTCDCLD 1322
Query: 421 GYSVKPEQGPACTDDDEC-ELGT-CDCHPAADCINLPGSFQCRCRDGW 466
GY + + C D +EC EL A CIN GS++C C G+
Sbjct: 1323 GYHLDTAK-MTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1369
Score = 44.0 bits (99), Expect = 0.001
Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
+G +C PL + + +CCCS +GKA CE CP GT A++ +C
Sbjct: 359 SGRQCMHPLSVHLTKQLCCCS-VGKA--GPHCEKCPLPGTAAFKEIC 402
Score = 43.6 bits (98), Expect = 0.002
Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DI+EC +C NG C NT G Y C C +GF SC+
Sbjct: 298 CQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Score = 41.1 bits (92), Expect = 0.010
Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
Query: 462 CRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
C G+ R + C+D++EC G C P C NT GS+RC C G+ D
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQ-GVC-PNGECLNTMGSYRCTCKIGFGPD 333
Score = 39.9 bits (89), Expect = 0.024
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
CS PL CC G+AWG Q C CP K +D Y LC
Sbjct: 1209 CSRPLVGKQTTYTECCCLYGEAWGMQ-CALCPLKDSDDYAQLC 1250
Score = 38.7 bits (86), Expect = 0.054
Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
Query: 417 QCPDGYSVKPEQGPACTDDDECEL-GTCDCHPAADCINLPGSFQCRCRDGWRGD 469
+C GY K C D +EC+L G C P +C+N GS++C C+ G+ D
Sbjct: 285 ECLPGY--KRVNNTFCQDINECQLQGVC---PNGECLNTMGSYRCTCKIGFGPD 333
Score = 38.7 bits (86), Expect = 0.054
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV 159
++NEC G+C +G C N +G + C C G+ D +CV
Sbjct: 300 DINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Score = 37.9 bits (84), Expect = 0.095
Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKK 39
G +C LP + + CC +G +WG +C+ CPKK
Sbjct: 239 GSQCGKALP-GLSKQEDCCGTVGTSWGFNKCQKCPKK 274
Score = 37.5 bits (83), Expect = 0.13
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCE--PCPKKGTDAYQNLC 48
C L +V + CCC++ G WG+ CE PCP GT + +C
Sbjct: 1032 CDNVLAPNVTKQECCCTS-GAGWGD-NCEIFPCPVLGTAEFTEMC 1074
Score = 32.3 bits (70), Expect = 4.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 397 QIPELCGAGSCHNTIGSFVCQCPDGYSVKP 426
Q+ +C G C NT+GS+ C C G+ P
Sbjct: 305 QLQGVCPNGECLNTMGSYRCTCKIGFGPDP 334
>AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming growth
factor beta binding protein 1 isoform LTBP-1S varian
protein.
Length = 1348
Score = 334 bits (821), Expect = 5e-91
Identities = 181/452 (40%), Positives = 225/452 (49%), Gaps = 42/452 (9%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
E+NEC P +CG G C NL +TC C+ GY + CVD++EC V +C G C
Sbjct: 500 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 559
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCE-CGHGMELA 236
NTEGSF C C G+ A + C+D+DEC D +C G CVNT G+FRCE C G +
Sbjct: 560 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHCVNTVGAFRCEYCDSGYRMT 618
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCV-CDEGYAQSTVKSHXXXXXXXXXXXX 295
R C+DIDEC + C + C N G+YQCV C EG+
Sbjct: 619 -QRGRCEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGF--RGWNGQCLDVDECLEPNV 674
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
C N GSY C+C +G+ D + CRDIDEC G C GQC+NT GS+ CTC
Sbjct: 675 CANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCTCG 733
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G SA AK C+DIDEC Q LC G C NT GSF
Sbjct: 734 QGYQLSA--AKDQCEDIDEC---------------------QHRHLCAHGQCRNTEGSFQ 770
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDGATCE 474
C C GY G C D +EC C DCIN GS+ C C DG++ D TC+
Sbjct: 771 CVCDQGYRAS-GLGDHCEDINECLEDKSVCQ-RGDCINTAGSYDCTCPDGFQLDDNKTCQ 828
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D++EC + G C P+ C NT+GSF C+C G+ G RT C DIDEC N+
Sbjct: 829 DINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADG-RT------CEDIDECVNNTV 880
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+G C NT G + C C GF DG+ C+
Sbjct: 881 CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV 912
Score = 305 bits (749), Expect = 3e-82
Identities = 168/442 (38%), Positives = 220/442 (49%), Gaps = 48/442 (10%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC LC GRC N G F C C G+ + C+DV+EC D VCG+G C
Sbjct: 541 VDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHC 599
Query: 177 HNTEGSFTC-HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC-ECGHGME 234
NT G+F C +C GY+ + C DIDEC N + C +CVN+ GS++C C G
Sbjct: 600 VNTVGAFRCEYCDSGYRMTQRGR-CEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGFR 657
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ C D+DEC + +C+NG C N G+Y C C +GY ++ H
Sbjct: 658 GWNGQ--CLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN 714
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C NT GS+ CTC +G+ L A C DIDEC C GQCRNT GS+ C C
Sbjct: 715 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVC 773
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G A+G C+DI+EC + KSV C G C NT GS+
Sbjct: 774 DQGY--RASGLGDHCEDINECLE-------------DKSV-------CQRGDCINTAGSY 811
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C CPDG+ + + C D +ECE C P +C+N GSF C C+ G+ DG T
Sbjct: 812 DCTCPDGFQL--DDNKTCQDINECEHPGL-CGPQGECLNTEGSFHCVCQQGFSISADGRT 868
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG--DGYGLRTVCCVYSCVDIDECA 530
CED+DEC+ NN C C NT GSFRCLC G++ DG G CVD++EC
Sbjct: 869 CEDIDECV-NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQG---------CVDVNECE 918
Query: 531 NDPTLCENGHCSNTPGGYECDC 552
+C C N G + C C
Sbjct: 919 LLSGVCGEAFCENVEGSFLCVC 940
Score = 250 bits (611), Expect = 1e-65
Identities = 141/351 (40%), Positives = 184/351 (52%), Gaps = 37/351 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTC-DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++EC P C +C N G + C C G+ N C+DV+EC + VC +GDC
Sbjct: 625 DIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR--GWNGQCLDVDEC-LEPNVCANGDC 680
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N EGS+ C C GY K C DIDEC + LC G+C NT GSFRC CG G +L+
Sbjct: 681 SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN-LCVNGQCKNTEGSFRCTCGQGYQLS 739
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+ C+DIDEC +C++G C N G++QCVCD+GY S + H
Sbjct: 740 AAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV 798
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTC 354
CQ C+NT GSY CTC +G+ L D ++C+DI+EC CG G+C NT GS+ C C
Sbjct: 799 CQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPGL-CGPQGECLNTEGSFHCVC 856
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGS 413
G SA G TC+DIDEC + +T+ C + G C NT GS
Sbjct: 857 QQGFSISADGR--TCEDIDECVN--NTV-------------------CDSHGFCDNTAGS 893
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
F C C G+ P+ G C D +ECEL + C A C N+ GSF C C D
Sbjct: 894 FRCLCYQGFQA-PQDGQGCVDVNECELLSGVCGEAF-CENVEGSFLCVCAD 942
Score = 230 bits (562), Expect = 1e-59
Identities = 142/458 (31%), Positives = 200/458 (43%), Gaps = 38/458 (8%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC LC +G+C+N G F C C GY+ + C D++EC+ +C G C
Sbjct: 706 DIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH-LCAHGQCR 763
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NTEGSF C C GY+A C DI+EC ++ ++C+ G C+NTAGS+ C C G +L
Sbjct: 764 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-D 822
Query: 238 DRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
D +C+DI+EC G+C G C N G++ CVC +G++ S
Sbjct: 823 DNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 881
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
H C NT GS+ C C +G+ DG+ C D++EC + CG C N GS+ C C
Sbjct: 882 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCA 941
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
D + + T Q C ST + + VD+ ++ L A C N + V
Sbjct: 942 D---ENQEYSPMTGQ----CRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNV 994
Query: 416 ----CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINL---PGSFQCRCRDGWRG 468
C C G D CE+ C A+ + F
Sbjct: 995 TKQECCCTSGAGW----------GDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEA 1044
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
G +D DECL C NT + C C G D L+ C D+DE
Sbjct: 1045 GGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQ-------CFDMDE 1097
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DP+ C +G C NT G Y C C A + C+
Sbjct: 1098 C-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI 1134
Score = 87.4 bits (207), Expect = 1e-16
Identities = 37/92 (40%), Positives = 53/92 (57%), Gaps = 4/92 (4%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVD---GVCG 172
+++ EC G C +GRC + G+TCDCF GY D+ TCVDVNEC+ ++ +C
Sbjct: 1246 ELQAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCK 1304
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
+ C NT+GS+ C C PGY D C ++
Sbjct: 1305 NAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1336
Score = 66.1 bits (154), Expect = 3e-10
Identities = 27/74 (36%), Positives = 43/74 (58%), Gaps = 4/74 (5%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADND---ALCRG 215
+ EC I++G C +G C + +TC C GY D CVD++EC + + +LC+
Sbjct: 1247 LQAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN 1305
Query: 216 GRCVNTAGSFRCEC 229
+C+NT GS++C C
Sbjct: 1306 AKCINTDGSYKCLC 1319
Score = 64.1 bits (149), Expect = 1e-09
Identities = 69/276 (25%), Positives = 100/276 (36%), Gaps = 32/276 (11%)
Query: 118 EVNECAAF-PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECE----IVDGVC- 171
+ +EC F +C +G C N G+ C C G D C D++EC+ +DG C
Sbjct: 1051 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCV 1110
Query: 172 ---GDGDCHNT-----EGSFTCHCRPGYKADDFSKICVDIDECADN---DALCRGGRCVN 220
G +C T + S RP + + V D C ++ + +C
Sbjct: 1111 NTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGK 1170
Query: 221 TAGSFRCECGHGMELAPDRLSC--KDIDECSITSGICSNG--------ACENQMGTYQCV 270
C C +G C KD D+ + I G A + Y
Sbjct: 1171 QTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPE 1230
Query: 271 CDEGYAQST-VKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDI 328
D + Q + S C++ CV Y C C +G+HL +C D+
Sbjct: 1231 ADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDV 1290
Query: 329 DEC---AGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
+EC C +C NT GSY C C G VPS
Sbjct: 1291 NECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS 1326
Score = 59.7 bits (138), Expect = 3e-08
Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICV 201
+C PGY++ + N C D+NEC++ GVC +G+C NT GS+ C C+ G+ D CV
Sbjct: 291 ECLPGYKRVN-NTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 346
Score = 56.0 bits (129), Expect = 3e-07
Identities = 27/61 (44%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 451 CINLPGSFQCRCRDGWRGDGA--TCEDVDEC--LTNNGGCHPRATCANTDGSFRCLCDTG 506
C+ + + C C DG+ D A TC DV+EC L N A C NTDGS++CLC G
Sbjct: 1263 CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1322
Query: 507 Y 507
Y
Sbjct: 1323 Y 1323
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/56 (42%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC 242
C PGYK + + C DI+EC +C G C+NT GS+RC C G P SC
Sbjct: 292 CLPGYKRVN-NTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 345
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/34 (50%), Positives = 24/34 (70%), Gaps = 1/34 (2%)
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+DI+EC + G+C NG C N MG+Y+C C G+
Sbjct: 304 CQDINECQL-QGVCPNGECLNTMGSYRCTCKIGF 336
Score = 47.2 bits (107), Expect = 2e-04
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 12/92 (13%)
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA---NDP 533
+EC NG C C + C C DGY L T +CVD++EC N
Sbjct: 1250 EECGILNG-CE-NGRCVRVQEGYTCDCF-----DGYHLDTA--KMTCVDVNECDELNNRM 1300
Query: 534 TLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+LC+N C NT G Y+C C G+ + C
Sbjct: 1301 SLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1332
Score = 46.8 bits (106), Expect = 2e-04
Identities = 36/105 (34%), Positives = 44/105 (41%), Gaps = 21/105 (20%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
+EC G C G+C YTC C DG A K TC D++EC D
Sbjct: 1250 EEC-GILNGCENGRCVRVQEGYTCDCFDGYHLDTA--KMTCVDVNEC------------D 1294
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
EL + LC C NT GS+ C C GY V ++ CT
Sbjct: 1295 ELNNRMS-----LCKNAKCINTDGSYKCLCLPGY-VPSDKPNYCT 1333
Score = 46.0 bits (104), Expect = 4e-04
Identities = 28/70 (40%), Positives = 35/70 (50%), Gaps = 9/70 (12%)
Query: 296 RCQHSCVNTPGSYH-----CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSY 350
+CQ C P SYH C G+ R + C+DI+EC C G+C NT+GSY
Sbjct: 273 KCQ-KCPKKP-SYHGYNQMMECLPGYK-RVNNTFCQDINECQLQG-VCPNGECLNTMGSY 328
Query: 351 TCTCTDGLVP 360
CTC G P
Sbjct: 329 RCTCKIGFGP 338
Score = 44.8 bits (101), Expect = 8e-04
Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 2/40 (5%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGT 41
+G +C PL + + +CCCS +GKAWG CE CP GT
Sbjct: 365 SGRQCMHPLSVHLTKQLCCCS-VGKAWG-PHCEKCPLPGT 402
Score = 44.0 bits (99), Expect = 0.001
Identities = 71/288 (24%), Positives = 99/288 (34%), Gaps = 38/288 (13%)
Query: 202 DIDECA-DNDALCRGGRCVNTAGSFRCECGHGMELAP------DRLSCKD----ID-ECS 249
D DEC +C+ G C+NT + C C G P D C+D ID +C
Sbjct: 1051 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCV 1110
Query: 250 ITSGICSNGACENQM----GTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVN 303
T G N C + M +C+ + + C V
Sbjct: 1111 NTEG-SYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVG 1169
Query: 304 TPGSY-HCTCR--EGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP 360
+Y C C E W ++ +D D+ A G+ R G D LV
Sbjct: 1170 KQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGR-RQPYGR------DALVD 1222
Query: 361 SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD 420
+ P I + S +ELQ + I C G C + C C D
Sbjct: 1223 FSEQYTPEADPY-----FIQDRFLNSFEELQAE-ECGILNGCENGRCVRVQEGYTCDCFD 1276
Query: 421 GYSVKPEQGPACTDDDEC-ELGT-CDCHPAADCINLPGSFQCRCRDGW 466
GY + + C D +EC EL A CIN GS++C C G+
Sbjct: 1277 GYHLDTAK-MTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1323
Score = 43.6 bits (98), Expect = 0.002
Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DI+EC +C NG C NT G Y C C +GF SC+
Sbjct: 304 CQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 346
Score = 41.1 bits (92), Expect = 0.010
Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
Query: 462 CRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
C G+ R + C+D++EC G C P C NT GS+RC C G+ D
Sbjct: 292 CLPGYKRVNNTFCQDINECQLQ-GVC-PNGECLNTMGSYRCTCKIGFGPD 339
Score = 39.9 bits (89), Expect = 0.024
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
CS PL CC G+AWG Q C CP K +D Y LC
Sbjct: 1163 CSRPLVGKQTTYTECCCLYGEAWGMQ-CALCPLKDSDDYAQLC 1204
Score = 38.7 bits (86), Expect = 0.054
Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
Query: 417 QCPDGYSVKPEQGPACTDDDECEL-GTCDCHPAADCINLPGSFQCRCRDGWRGD 469
+C GY K C D +EC+L G C P +C+N GS++C C+ G+ D
Sbjct: 291 ECLPGY--KRVNNTFCQDINECQLQGVC---PNGECLNTMGSYRCTCKIGFGPD 339
Score = 38.7 bits (86), Expect = 0.054
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV 159
++NEC G+C +G C N +G + C C G+ D +CV
Sbjct: 306 DINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 346
Score = 37.9 bits (84), Expect = 0.095
Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKK 39
G +C LP + + CC +G +WG +C+ CPKK
Sbjct: 245 GSQCGKALP-GLSKQEDCCGTVGTSWGFNKCQKCPKK 280
Score = 37.5 bits (83), Expect = 0.13
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCE--PCPKKGTDAYQNLC 48
C L +V + CCC++ G WG+ CE PCP GT + +C
Sbjct: 986 CDNVLAPNVTKQECCCTS-GAGWGD-NCEIFPCPVLGTAEFTEMC 1028
Score = 32.3 bits (70), Expect = 4.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 397 QIPELCGAGSCHNTIGSFVCQCPDGYSVKP 426
Q+ +C G C NT+GS+ C C G+ P
Sbjct: 311 QLQGVCPNGECLNTMGSYRCTCKIGFGPDP 340
>AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein.
Length = 697
Score = 332 bits (816), Expect = 2e-90
Identities = 180/451 (39%), Positives = 224/451 (49%), Gaps = 42/451 (9%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
+NEC P +CG G C NL +TC C+ GY + CVD++EC V +C G C N
Sbjct: 1 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN 60
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCE-CGHGMELAP 237
TEGSF C C G+ A + C+D+DEC D +C G CVNT G+FRCE C G +
Sbjct: 61 TEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHCVNTVGAFRCEYCDSGYRMT- 118
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCV-CDEGYAQSTVKSHXXXXXXXXXXXXR 296
R C+DIDEC + C + C N G+YQCV C EG+
Sbjct: 119 QRGRCEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGF--RGWNGQCLDVDECLEPNVC 175
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C N GSY C+C +G+ D + CRDIDEC G C GQC+NT GS+ CTC
Sbjct: 176 ANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCTCGQ 234
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G SA AK C+DIDEC Q LC G C NT GSF C
Sbjct: 235 GYQLSA--AKDQCEDIDEC---------------------QHRHLCAHGQCRNTEGSFQC 271
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDGATCED 475
C GY G C D +EC C DCIN GS+ C C DG++ D TC+D
Sbjct: 272 VCDQGYRAS-GLGDHCEDINECLEDKSVCQ-RGDCINTAGSYDCTCPDGFQLDDNKTCQD 329
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
++EC + G C P+ C NT+GSF C+C G+ G RT C DIDEC N+
Sbjct: 330 INEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADG-RT------CEDIDECVNNTVC 381
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+G C NT G + C C GF DG+ C+
Sbjct: 382 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV 412
Score = 305 bits (749), Expect = 3e-82
Identities = 168/442 (38%), Positives = 220/442 (49%), Gaps = 48/442 (10%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC LC GRC N G F C C G+ + C+DV+EC D VCG+G C
Sbjct: 41 VDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHC 99
Query: 177 HNTEGSFTC-HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC-ECGHGME 234
NT G+F C +C GY+ + C DIDEC N + C +CVN+ GS++C C G
Sbjct: 100 VNTVGAFRCEYCDSGYRMTQRGR-CEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGFR 157
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ C D+DEC + +C+NG C N G+Y C C +GY ++ H
Sbjct: 158 GWNGQ--CLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN 214
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C NT GS+ CTC +G+ L A C DIDEC C GQCRNT GS+ C C
Sbjct: 215 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVC 273
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G A+G C+DI+EC + KSV C G C NT GS+
Sbjct: 274 DQGY--RASGLGDHCEDINECLE-------------DKSV-------CQRGDCINTAGSY 311
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGAT 472
C CPDG+ + + C D +ECE C P +C+N GSF C C+ G+ DG T
Sbjct: 312 DCTCPDGFQL--DDNKTCQDINECEHPGL-CGPQGECLNTEGSFHCVCQQGFSISADGRT 368
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG--DGYGLRTVCCVYSCVDIDECA 530
CED+DEC+ NN C C NT GSFRCLC G++ DG G CVD++EC
Sbjct: 369 CEDIDECV-NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQG---------CVDVNECE 418
Query: 531 NDPTLCENGHCSNTPGGYECDC 552
+C C N G + C C
Sbjct: 419 LLSGVCGEAFCENVEGSFLCVC 440
Score = 250 bits (611), Expect = 1e-65
Identities = 141/351 (40%), Positives = 184/351 (52%), Gaps = 37/351 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTC-DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++EC P C +C N G + C C G+ N C+DV+EC + VC +GDC
Sbjct: 125 DIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR--GWNGQCLDVDEC-LEPNVCANGDC 180
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N EGS+ C C GY K C DIDEC + LC G+C NT GSFRC CG G +L+
Sbjct: 181 SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN-LCVNGQCKNTEGSFRCTCGQGYQLS 239
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+ C+DIDEC +C++G C N G++QCVCD+GY S + H
Sbjct: 240 AAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV 298
Query: 297 CQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTC 354
CQ C+NT GSY CTC +G+ L D ++C+DI+EC CG G+C NT GS+ C C
Sbjct: 299 CQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPGL-CGPQGECLNTEGSFHCVC 356
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGS 413
G SA G TC+DIDEC + +T+ C + G C NT GS
Sbjct: 357 QQGFSISADGR--TCEDIDECVN--NTV-------------------CDSHGFCDNTAGS 393
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
F C C G+ P+ G C D +ECEL + C A C N+ GSF C C D
Sbjct: 394 FRCLCYQGFQA-PQDGQGCVDVNECELLSGVCGEAF-CENVEGSFLCVCAD 442
Score = 230 bits (563), Expect = 9e-60
Identities = 142/458 (31%), Positives = 200/458 (43%), Gaps = 38/458 (8%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC LC +G+C+N G F C C GY+ + C D++EC+ +C G C
Sbjct: 206 DIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH-LCAHGQCR 263
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NTEGSF C C GY+A C DI+EC ++ ++C+ G C+NTAGS+ C C G +L
Sbjct: 264 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-D 322
Query: 238 DRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
D +C+DI+EC G+C G C N G++ CVC +G++ S
Sbjct: 323 DNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 381
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
H C NT GS+ C C +G+ DG+ C D++EC + CG C N GS+ C C
Sbjct: 382 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCA 441
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
D + + T Q C ST + + VD+ ++ L A C N + V
Sbjct: 442 D---ENQEYSPMTGQ----CRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNV 494
Query: 416 ----CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINL---PGSFQCRCRDGWRG 468
C C G D CE+ C A+ + F
Sbjct: 495 TKQECCCTSGVGW----------GDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEA 544
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
G +D DECL C NT + C C G D L+ C D+DE
Sbjct: 545 GGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQ-------CFDMDE 597
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DP+ C +G C NT G Y C C A + C+
Sbjct: 598 C-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI 634
Score = 37.1 bits (82), Expect = 0.17
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCE--PCPKKGTDAYQNLC 48
C L +V + CCC++ G WG+ CE PCP GT + +C
Sbjct: 486 CDNVLAPNVTKQECCCTS-GVGWGD-NCEIFPCPVLGTAEFTEMC 528
>AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.
Length = 1365
Score = 331 bits (814), Expect = 3e-90
Identities = 154/361 (42%), Positives = 200/361 (55%), Gaps = 24/361 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NEC P LC HG+CRN +G F C C G+ DS+ C D++EC I +CG G C
Sbjct: 1028 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT G F C C GY++ K C+DIDEC + LCRGG C NT GS+RCEC G +L+
Sbjct: 1088 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS 1147
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
P+ +C DI+EC +++ +C NG C N +G YQC C+ GY + +
Sbjct: 1148 PNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGG 1207
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C+ C N+ GSY C+C+ G+ L D RSC DIDEC C GGQC N G Y C C D
Sbjct: 1208 CETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYD 1267
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A+ TC D++EC DL P +C +G+C NT GSF+C
Sbjct: 1268 GFM--ASEDMKTCVDVNEC-DL-------------------NPNICLSGTCENTKGSFIC 1305
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
C GYS K + CTD +ECE+G +C A C N GSF+C C GW GDG C D+
Sbjct: 1306 HCDMGYSGKKGK-TGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDL 1364
Query: 477 D 477
D
Sbjct: 1365 D 1365
Score = 248 bits (606), Expect = 5e-65
Identities = 163/487 (33%), Positives = 218/487 (44%), Gaps = 74/487 (15%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVN-----------ECEI 166
+++EC FPG+C +G C N G F C C G D+ C+D+ EC +
Sbjct: 910 DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTL 969
Query: 167 -------VDGVC-------GDGDCH-----NT-EGSFTCHCRPGYKADDFSK---ICVDI 203
+D C G +C NT E C PG+ + + DI
Sbjct: 970 PIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDI 1029
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
+EC +LC G+C NT GSF+C C G L + +C DIDEC I+ +C G C N
Sbjct: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
Query: 264 MGTYQCVCDEGYAQS-TVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRAD 321
G ++C CDEGY + + C+ C NT GSY C C G L +
Sbjct: 1090 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1149
Query: 322 GRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLIST 381
+C DI+EC A C G+C N +G Y C C G + + C DIDEC+
Sbjct: 1150 ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY--HSTPDRLFCVDIDECS----- 1202
Query: 382 IIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
IM E C N+ GS+ C C G+++ P+Q +CTD DECE
Sbjct: 1203 -IMNGGCET---------------FCTNSEGSYECSCQPGFALMPDQR-SCTDIDECEDN 1245
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTDGSF 499
C C N+PG ++C C DG+ D TC DV+EC N C TC NT GSF
Sbjct: 1246 PNICD-GGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLS-GTCENTKGSF 1303
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYECDCDVGFTR 558
C CD GY G +T C DI+EC C ++ C+NT G ++C C G+
Sbjct: 1304 ICHCDMGYSGKKG--KT-----GCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW-- 1354
Query: 559 AADGRSC 565
DG C
Sbjct: 1355 IGDGIKC 1361
Score = 241 bits (590), Expect = 5e-63
Identities = 139/394 (35%), Positives = 189/394 (47%), Gaps = 22/394 (5%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C LC +GRC G C+C G++ D + C+DV+ECE C G+C N +G
Sbjct: 453 CQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGE-CIDVDECE--KNPCAGGECINNQG 509
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
S+TC CR GY++ C DIDEC N +C GRC+NT GSF C C G + D +
Sbjct: 510 SYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 569
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C+D+DECSI + +C NG C N+ G+++C+C G+ ++ + C
Sbjct: 570 CEDMDECSIRN-MCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRC 628
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDI---DECAGGARPCGGGQC-RNTVGSYT---CTC 354
VNT GSY C C G + DGR C D C GG + GQC + G+ T C C
Sbjct: 629 VNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYK---RGQCIKPLFGAVTKSECCC 685
Query: 355 TDGLVPSAAGAKP-TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
+P Q+ E L S+ M+ + P++C G C N G+
Sbjct: 686 ASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGT 745
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG--WRGDGA 471
+ C C GY V G C D +EC L + C C N PGSF C C G ++ D
Sbjct: 746 YKCICNSGYEV-DSTGKNCVDINECVLNSLLC-DNGQCRNTPGSFVCTCPKGFIYKPDLK 803
Query: 472 TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDT 505
TCED+DEC + C C N+ GSF C C +
Sbjct: 804 TCEDIDEC--ESSPC-INGVCKNSPGSFICECSS 834
Score = 239 bits (584), Expect = 2e-62
Identities = 166/508 (32%), Positives = 224/508 (44%), Gaps = 94/508 (18%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDV-----------NECEI 166
+++EC + P C +G C+N G F C+C D C++ CEI
Sbjct: 807 DIDECESSP--CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEI 864
Query: 167 -VDGVCGDGDCHNTEGSF------TCH----CRPGYKADDFSKICVDIDECADNDALCRG 215
++G C ++ G+ C C GY ++ C DIDEC +C+
Sbjct: 865 NINGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQ-CEDIDECEVFPGVCKN 923
Query: 216 GRCVNTAGSFRCECGHGMELAPDRLSCKDI-----------DECSITSG--------ICS 256
G CVNT GSF+C+C GM L C DI +EC++ CS
Sbjct: 924 GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCS 983
Query: 257 NGA------CEN----QMGTYQCVCDEG--YAQSTV---KSHXXXXXXXXXXXXRCQHS- 300
GA CE Y+ +C G +A + K C H
Sbjct: 984 VGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGK 1043
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP 360
C NT GS+ C C G+ L ++ R+C DIDEC CG GQC NT G + C C +G
Sbjct: 1044 CRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYES 1103
Query: 361 SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD 420
K C DIDEC Q+ P LC G CHNT GS+ C+CP
Sbjct: 1104 GFMMMK-NCMDIDEC---------------QRD-----PLLCRGGVCHNTEGSYRCECPP 1142
Query: 421 GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDE 478
G+ + P AC D +ECEL C P C+NL G +QC C G+ D C D+DE
Sbjct: 1143 GHQLSPNIS-ACIDINECELSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1200
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN 538
C NGGC C N++GS+ C C G+ + SC DIDEC ++P +C+
Sbjct: 1201 CSIMNGGCE--TFCTNSEGSYECSCQPGFA-------LMPDQRSCTDIDECEDNPNICDG 1251
Query: 539 GHCSNTPGGYECDCDVGFTRAADGRSCL 566
G C+N PG Y C C GF + D ++C+
Sbjct: 1252 GQCTNIPGEYRCLCYDGFMASEDMKTCV 1279
Score = 223 bits (546), Expect = 1e-57
Identities = 155/464 (33%), Positives = 202/464 (43%), Gaps = 47/464 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NECA P +C +G C NL G + C C GYE DS CVD+NEC + +C +G C
Sbjct: 723 DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCR 782
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT GSF C C G+ K C DIDEC + C G C N+ GSF CEC L P
Sbjct: 783 NTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSSESTLDP 840
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
+ C G C + + C+ +T+KS C
Sbjct: 841 TKTIC-----IETIKGTCWQTVIDGR-------CEININGATLKSQ-CCSSLGAAWGSPC 887
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
C P C +G+ R G C DIDEC C G C NT GS+ C C G
Sbjct: 888 T-LCQVDP-----ICGKGYS-RIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSG 940
Query: 358 LVPSAAGAKPTCQDI--DEC----ADLISTIIMMS---VDELQKSVDPQI-PELCGAGSC 407
+ A G C DI + C D T+ + +D SV E C
Sbjct: 941 MTLDATGR--ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPM 998
Query: 408 HNTIG-SFVCQCPDGYSVK--PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
NT +C G++ K P D +EC++ C C N GSF+CRC
Sbjct: 999 RNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLC-THGKCRNTIGSFKCRCDS 1057
Query: 465 GWRGDG--ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ D C D+DEC + C R C NT G F C CD GY+ G+ + + +
Sbjct: 1058 GFALDSEERNCTDIDECRISPDLC-GRGQCVNTPGDFECKCDEGYE-SGFMM-----MKN 1110
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C+DIDEC DP LC G C NT G Y C+C G + + +C+
Sbjct: 1111 CMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACI 1154
Score = 223 bits (546), Expect = 1e-57
Identities = 149/461 (32%), Positives = 206/461 (44%), Gaps = 76/461 (16%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKIC--VD 202
C GY + K C D++ECE+ GVC +G C NT GSF C C G D +IC +
Sbjct: 896 CGKGYSR-IKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIR 954
Query: 203 IDEC--ADNDALCR---GGR------CVNTA---GSFRCE-------------CGHGMEL 235
++ C D C GR C + G+ CE C G
Sbjct: 955 LETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGF 1014
Query: 236 APDRLS-----CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
A ++ KDI+EC + +C++G C N +G+++C CD G+A + + +
Sbjct: 1015 ATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDEC 1074
Query: 291 XXXXXRC-QHSCVNTPGSYHCTCREGWHLR-ADGRSCRDIDECAGGARPCGGGQCRNTVG 348
C + CVNTPG + C C EG+ ++C DIDEC C GG C NT G
Sbjct: 1075 RISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEG 1134
Query: 349 SYTCTCTDG--LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
SY C C G L P+ + C DI+EC EL LC G
Sbjct: 1135 SYRCECPPGHQLSPNISA----CIDINEC-------------ELSA-------HLCPNGR 1170
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N IG + C C GY P++ C D DEC + C C N GS++C C+ G+
Sbjct: 1171 CVNLIGKYQCACNPGYHSTPDR-LFCVDIDECSIMNGGCETF--CTNSEGSYECSCQPGF 1227
Query: 467 R--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
D +C D+DEC N C C N G +RCLC G+ ++T CV
Sbjct: 1228 ALMPDQRSCTDIDECEDNPNICDG-GQCTNIPGEYRCLCYDGFMASE-DMKT------CV 1279
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
D++EC +P +C +G C NT G + C CD+G++ C
Sbjct: 1280 DVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGC 1320
Score = 215 bits (525), Expect = 3e-55
Identities = 153/467 (32%), Positives = 198/467 (42%), Gaps = 63/467 (13%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC +C +GRC N G F C C G+ C D++EC I +C +G C
Sbjct: 530 DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI-RNMCLNGMCI 588
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N +GSF C C+PG++ + C DI+EC + +C GRCVNT GS+RCEC G+ +
Sbjct: 589 NEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRCECFPGLAVGL 647
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
D C D S G G QC+ + + KS C
Sbjct: 648 DGRVCVDTHMRSTCYGGYKRG---------QCI--KPLFGAVTKSECCCASTEYAFGEPC 696
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
Q Y C G + + G DI+ECA C G C N G+Y C C G
Sbjct: 697 QPCPAQNSAEYQALCSSGPGMTSAG---SDINECALDPDICPNGICENLRGTYKCICNSG 753
Query: 358 LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQ 417
+ G C DI+EC ++ S+ LC G C NT GSFVC
Sbjct: 754 YEVDSTG--KNCVDINEC-------VLNSL-------------LCDNGQCRNTPGSFVCT 791
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD-------- 469
CP G+ KP+ C D DECE C C N PGSF C C D
Sbjct: 792 CPKGFIYKPDL-KTCEDIDECESSPC---INGVCKNSPGSFICECSSESTLDPTKTICIE 847
Query: 470 --GATCED--VD-ECLTNNGGCHPRATCANTDGS---FRC-LCDTG-YKGDGYGLRTVCC 519
TC +D C N G ++ C ++ G+ C LC G GY
Sbjct: 848 TIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGT- 906
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DIDEC P +C+NG C NT G ++C C G T A GR CL
Sbjct: 907 --QCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICL 951
Score = 201 bits (490), Expect = 6e-51
Identities = 144/478 (30%), Positives = 197/478 (41%), Gaps = 73/478 (15%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++NEC LC +G+CRN G F C C G+ TC D++ECE C +G C
Sbjct: 764 VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECE--SSPCINGVC 821
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD----------ID-ECADN-DALCRGGRCVNTAGS 224
N+ GSF C C D IC++ ID C N + +C ++ G+
Sbjct: 822 KNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGA 881
Query: 225 ------FRCE----CGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
C+ CG G C+DIDEC + G+C NG C N G+++C C G
Sbjct: 882 AWGSPCTLCQVDPICGKGYSRIKG-TQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSG 940
Query: 275 YAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG 334
R + +C CT R D C A G
Sbjct: 941 M--------TLDATGRICLDIRLE-TCFLRYEDEECTLPIAGRHRMDACCCS--VGAAWG 989
Query: 335 ARPCGGGQCRNTVGSYTCTCTDG---LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQ 391
C RNT Y C G KP +DI+EC
Sbjct: 990 TEECEECPMRNT-PEYEELCPRGPGFATKEITNGKPFFKDINEC---------------- 1032
Query: 392 KSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
IP LC G C NTIGSF C+C G+++ E+ CTD DEC + D C
Sbjct: 1033 ----KMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEE-RNCTDIDECRISP-DLCGRGQC 1086
Query: 452 INLPGSFQCRCRDGWRGD---GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
+N PG F+C+C +G+ C D+DEC + C C NT+GS+RC C G++
Sbjct: 1087 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCR-GGVCHNTEGSYRCECPPGHQ 1145
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ +C+DI+EC LC NG C N G Y+C C+ G+ D C+
Sbjct: 1146 LSPN-------ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCV 1196
Score = 200 bits (488), Expect = 1e-50
Identities = 97/259 (37%), Positives = 132/259 (50%), Gaps = 7/259 (2%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+++EC P LC G C N G + C+C PG++ C+D+NECE+ +C +G C
Sbjct: 1112 MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRC 1171
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G + C C PGY + CVDIDEC+ + C C N+ GS+ C C G L
Sbjct: 1172 VNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCE-TFCTNSEGSYECSCQPGFALM 1230
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXX 295
PD+ SC DIDEC IC G C N G Y+C+C +G+ A +K+
Sbjct: 1231 PDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNI 1290
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTC 354
+C NT GS+ C C G+ + C DI+EC GA CG C NT GS+ C+C
Sbjct: 1291 CLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSC 1350
Query: 355 TDGLVPSAAGAKPTCQDID 373
+ G + G K C D+D
Sbjct: 1351 SPGWI--GDGIK--CTDLD 1365
Score = 172 bits (418), Expect = 3e-42
Identities = 124/389 (31%), Positives = 171/389 (43%), Gaps = 61/389 (15%)
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
D C LC+ GRC+ T GS RCEC G +L R C D+DEC C+ G C N
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQL-DLRGECIDVDECE--KNPCAGGECINN 507
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADG 322
G+Y C C GY + ++ C + C+NT GS+HC C G+H+ DG
Sbjct: 508 QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDG 567
Query: 323 RSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTI 382
++C D+DEC+ C G C N GS+ C C G ++ G C+DI+EC
Sbjct: 568 KNCEDMDECS-IRNMCLNGMCINEDGSFKCICKPGFQLASDGR--YCKDINEC------- 617
Query: 383 IMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGT 442
+ P +C G C NT GS+ C+C G +V + G C D T
Sbjct: 618 --------------ETPGICMNGRCVNTDGSYRCECFPGLAVGLD-GRVCVDTH--MRST 660
Query: 443 C-DCHPAADCIN-LPGSF---QCRCRDGWRGDGATCEDVD-------ECLTNNGGCHPRA 490
C + CI L G+ +C C G C+ + L ++G P
Sbjct: 661 CYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG---PGM 717
Query: 491 TCANTDGSFRCLCDTGYKGDGY--GLR-TVCCV-----------YSCVDIDECANDPTLC 536
T A +D + C D +G LR T C+ +CVDI+EC + LC
Sbjct: 718 TSAGSDIN-ECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLC 776
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+NG C NTPG + C C GF D ++C
Sbjct: 777 DNGQCRNTPGSFVCTCPKGFIYKPDLKTC 805
Score = 130 bits (313), Expect = 2e-29
Identities = 98/341 (28%), Positives = 137/341 (40%), Gaps = 29/341 (8%)
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ-H 299
+C+D+DEC G+C G C N +G+++C C G+ + V C+
Sbjct: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN----TVGSYTCTCT 355
C NT SY C C G++ DG C D+ G+C N ++ C C
Sbjct: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDV-RPGYCYTALTNGRCSNQLPQSITKMQCCCD 361
Query: 356 DGLV--PSAAGAKPTC-----QDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCH 408
G P A C +D ++ + +I + + P P L
Sbjct: 362 AGRCWSPGVTVAPEMCPIRATEDFNKLCS-VPMVIPGRPEYPPPPLGPIPPVLPVPPGFP 420
Query: 409 NTIGSFVCQCPDGY---SVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
V + P Y S +P + D C+L C CI PGS +C C G
Sbjct: 421 PGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGR-CIPTPGSCRCECNKG 479
Query: 466 WRGD-GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
++ D C DVDEC N C C N GS+ C C GY+ RT C
Sbjct: 480 FQLDLRGECIDVDECEKN--PC-AGGECINNQGSYTCQCRAGYQST--LTRT-----ECR 529
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DIDEC + +C NG C NT G + C C+ GF DG++C
Sbjct: 530 DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNC 570
Score = 125 bits (302), Expect = 4e-28
Identities = 82/231 (35%), Positives = 99/231 (42%), Gaps = 39/231 (16%)
Query: 338 CGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
C G+C T GS C C G G C D+DEC +P
Sbjct: 460 CQNGRCIPTPGSCRCECNKGFQLDLRGE---CIDVDECEK-----------------NP- 498
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
C G C N GS+ CQC GY + C D DEC C+ CIN GS
Sbjct: 499 ----CAGGECINNQGSYTCQCRAGYQSTLTR-TECRDIDECLQNGRICNNGR-CINTDGS 552
Query: 458 FQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
F C C G+ DG CED+DEC N + C N DGSF+C+C G++ G
Sbjct: 553 FHCVCNAGFHVTRDGKNCEDMDECSIRNMCLN--GMCINEDGSFKCICKPGFQLASDGRY 610
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DI+EC P +C NG C NT G Y C+C G DGR C+
Sbjct: 611 -------CKDINECET-PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV 653
Score = 113 bits (273), Expect = 1e-24
Identities = 52/134 (38%), Positives = 74/134 (55%), Gaps = 5/134 (3%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
C G+ + + C DV+EC+ + G+C G+C NT GSF C C G+K ++ S+ C DID
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 290
Query: 205 ECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDI--DEC--SITSGICSNGAC 260
EC+ +C GG C NT S+ C+C G +PD C D+ C ++T+G CSN
Sbjct: 291 ECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSN-QL 349
Query: 261 ENQMGTYQCVCDEG 274
+ QC CD G
Sbjct: 350 PQSITKMQCCCDAG 363
Score = 96.3 bits (229), Expect = 3e-19
Identities = 86/309 (27%), Positives = 119/309 (38%), Gaps = 45/309 (14%)
Query: 136 NLLGG-FTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYK 192
N+ G + C PG++ + C V + DG C + C G C G +
Sbjct: 57 NVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSC--GSR 114
Query: 193 ADDFSKI-CVDIDECADNDALCRGGRCVNTAGSFRCECG---HGMELAPDRLSCKDIDEC 248
+ I C++ C+D+ LC+ G G CE G G +AP+R C
Sbjct: 115 SIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNR--------C 166
Query: 249 SITSGICSNGACENQMGTYQC--VCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHSCVNTP 305
+ T G + CE T C V Q + R H C P
Sbjct: 167 ACTYGF-TGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCP 225
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGA 365
H CR G+ +C+D+DEC C GG C NTVGS+ C C G +
Sbjct: 226 AQPH-PCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQ 284
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVK 425
K C+DIDEC+ IP +C G C NT+ S+ C+CP G+
Sbjct: 285 K--CEDIDECS--------------------TIPGICEGGECTNTVSSYFCKCPPGFYTS 322
Query: 426 PEQGPACTD 434
P+ G C D
Sbjct: 323 PD-GTRCID 330
Score = 94.7 bits (225), Expect = 8e-19
Identities = 85/275 (30%), Positives = 107/275 (38%), Gaps = 35/275 (12%)
Query: 297 CQHSCVNTPGSYH--CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+HSC + S CTC G + G R I C R GG C + C C
Sbjct: 85 CRHSCGDGFCSRPNMCTCPSGQIAPSCGS--RSIQHC--NIRCMNGGSCSDD----HCLC 136
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + + G +P C+ C + + PQ G C I +
Sbjct: 137 QKGYIGTHCG-QPVCES--GCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQ 193
Query: 415 VCQCPDGYSVKPEQGPACTDDDECE-LGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT- 472
+CQ G CT C +G HP C P CR G+ + T
Sbjct: 194 MCQ-------GQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHP----CRRGFIPNIRTG 242
Query: 473 -CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
C+DVDEC G C C NT GSF C C G+K L V C DIDEC+
Sbjct: 243 ACQDVDECQAIPGLCQG-GNCINTVGSFECKCPAGHK-----LNEVS--QKCEDIDECST 294
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
P +CE G C+NT Y C C GF + DG C+
Sbjct: 295 IPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCI 329
Score = 91.5 bits (217), Expect = 7e-18
Identities = 39/103 (37%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC A PGLC G C N +G F C C G++ + + C D++EC + G+C G+C
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 305
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVN 220
NT S+ C C PG+ C+D+ AL GRC N
Sbjct: 306 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTAL-TNGRCSN 347
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C+ P+ CCCS +G AWG + CE CP + T Y+ LC
Sbjct: 967 CTLPIAGRHRMDACCCS-VGAAWGTEECEECPMRNTPEYEELC 1008
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 1 MTGGRCSGPLPTDVLRAVCCCSALGKAWG---NQRCEPCPKKGTDAYQNLCIAVGTLLP 56
+T GRCS LP + + CCC A G+ W E CP + T+ + LC +V ++P
Sbjct: 340 LTNGRCSNQLPQSITKMQCCCDA-GRCWSPGVTVAPEMCPIRATEDFNKLC-SVPMVIP 396
Score = 43.6 bits (98), Expect = 0.002
Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
G+C PL V ++ CCC++ A+G + C+PCP + + YQ LC
Sbjct: 668 GQCIKPLFGAVTKSECCCASTEYAFG-EPCQPCPAQNSAEYQALC 711
Score = 35.5 bits (78), Expect = 0.51
Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCP 37
C G L V CC+ +G+AWG+ CE CP
Sbjct: 195 CQGQLSGIVCTKTLCCATVGRAWGHP-CEMCP 225
>Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein.
Length = 1821
Score = 299 bits (734), Expect = 2e-80
Identities = 171/457 (37%), Positives = 229/457 (50%), Gaps = 52/457 (11%)
Query: 119 VNECAA-FPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++ CAA +CG G C NL G+ C C PGY+ C D NEC + D G G C
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNEC-LRDPCQGKGRCI 903
Query: 178 NTEGSFTCHCRPGY--KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
N GS++C C PGY ++ C DI+EC + +C GG+C NT GS+ CEC G +
Sbjct: 904 NRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQGY-I 961
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCV-CDEGYAQSTVKSHXXXXXXXXXXX 294
+ C+DI+EC G C +G C N G+Y C+ C+EGY +S
Sbjct: 962 MVRKGHCQDINECR-HPGTCPDGRCVNSPGSYTCLACEEGYRG---QSGSCVDVNECLTP 1017
Query: 295 XRCQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H C N GS+ C+C +G+ + +D + C+D+DECA A C G C NT GS+ C+
Sbjct: 1018 GVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRA-SCPTGLCLNTEGSFACS 1076
Query: 354 -CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G + G C+D+DECA P +C +G C NT G
Sbjct: 1077 ACENGYWVNEDGT--ACEDLDECA---------------------FPGVCPSGVCTNTAG 1113
Query: 413 SFVCQ-CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDG 470
SF C+ C GY P G +C D DECE C +C N GS+QC C G++ +G
Sbjct: 1114 SFSCKDCDGGYRPSP-LGDSCEDVDECEDPQSSC-LGGECKNTVGSYQCLCPQGFQLANG 1171
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
CEDV+EC+ C P C N+ GSF CLC G+ G SC D+DECA
Sbjct: 1172 TVCEDVNECM-GEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGT-------SCQDVDECA 1223
Query: 531 -NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
DP C GHC NT G + C C+ GF + + C+
Sbjct: 1224 TTDP--CVGGHCVNTEGSFNCLCETGFQPSPESGECV 1258
Score = 264 bits (647), Expect = 6e-70
Identities = 152/393 (38%), Positives = 189/393 (48%), Gaps = 35/393 (8%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++VNEC PG+C HG+C NL G F C C GYE S C DV+EC C G C
Sbjct: 1009 VDVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECAS-RASCPTGLC 1066
Query: 177 HNTEGSFTCH-CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC-ECGHGME 234
NTEGSF C C GY ++ C D+DECA +C G C NTAGSF C +C G
Sbjct: 1067 LNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTNTAGSFSCKDCDGGYR 1125
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+P SC+D+DEC C G C+N +G+YQC+C +G+ +
Sbjct: 1126 PSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEH 1185
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+N+ GS+ C C G+ G SC+D+DECA PC GG C NT GS+ C C
Sbjct: 1186 CAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECAT-TDPCVGGHCVNTEGSFNCLC 1244
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G PS + C DIDEC D DP +CG C N+ GS+
Sbjct: 1245 ETGFQPSPESGE--CVDIDECEDY---------------GDP----VCGTWKCENSPGSY 1283
Query: 415 VC--QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
C C G+ + P C D DEC T C C N GSF+C C G+ G
Sbjct: 1284 RCVLGCQPGFHMAPNGD--CIDIDECANDTM-CGSHGFCDNTDGSFRCLCDQGFEISPSG 1340
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C DV+EC C A C N +GSF CLC
Sbjct: 1341 WDCVDVNECELMLAVC-GAALCENVEGSFLCLC 1372
Score = 210 bits (513), Expect = 1e-53
Identities = 135/454 (29%), Positives = 185/454 (40%), Gaps = 26/454 (5%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC C G C+N +G + C C G++ + C DVNEC + G+C
Sbjct: 1135 DVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGEEHCAPHGECL 1193
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N+ GSF C C PG+ + + C D+DECA D C GG CVNT GSF C C G + +P
Sbjct: 1194 NSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDP-CVGGHCVNTEGSFNCLCETGFQPSP 1252
Query: 238 DRLSCKDIDECS-ITSGICSNGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXX 294
+ C DIDEC +C CEN G+Y+CV C G+ +
Sbjct: 1253 ESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTM 1312
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C NT GS+ C C +G+ + G C D++EC CG C N GS+ C C
Sbjct: 1313 CGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLC 1372
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
L A + C+ +S +D + G C + +G
Sbjct: 1373 ASDLEEYDA-QEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQK-GHAPCSSVLGRN 1430
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINL--PGSFQCRCRDGWRGDGAT 472
Q QG T D C+L C +A+ + G W
Sbjct: 1431 TTQA----ECCCTQG--ATWGDACDL--CPSEDSAEFSEICPSGKGYIPVEGAWTFGQTM 1482
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
D DEC+ G P C NT + CLC+ G+ D + C D DEC +
Sbjct: 1483 YTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKK-------CEDHDECQD- 1534
Query: 533 PTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CENG C NT G + C C T + C+
Sbjct: 1535 -LACENGECVNTEGSFHCFCSPPLTLDLSQQRCM 1567
Score = 92.3 bits (219), Expect = 4e-18
Identities = 38/81 (46%), Positives = 53/81 (65%), Gaps = 4/81 (4%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDG---VCGD 173
++ EC G C +GRC + G+TCDCF G++ D+ + CVDVNEC+ ++G +C
Sbjct: 1732 LQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH 1790
Query: 174 GDCHNTEGSFTCHCRPGYKAD 194
G C NTEGS+ CHC PGY A+
Sbjct: 1791 GYCENTEGSYRCHCSPGYVAE 1811
Score = 88.6 bits (210), Expect = 5e-17
Identities = 44/122 (36%), Positives = 65/122 (53%), Gaps = 6/122 (4%)
Query: 117 MEVNECAAFPG-LCGHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGD 173
++++EC + +CG +C N G + C C PG+ + N C+D++EC D +CG
Sbjct: 1258 VDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHM-APNGDCIDIDECAN-DTMCGS 1315
Query: 174 -GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
G C NT+GSF C C G++ CVD++EC A+C C N GSF C C
Sbjct: 1316 HGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASD 1375
Query: 233 ME 234
+E
Sbjct: 1376 LE 1377
Score = 81.8 bits (193), Expect = 6e-15
Identities = 36/86 (41%), Positives = 51/86 (59%), Gaps = 3/86 (3%)
Query: 118 EVNECAAF-PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+ +EC F PGLC +GRC N + G+ C C PG+ D+ + C D +EC+ D C +G+C
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ--DLACENGEC 1542
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD 202
NTEGSF C C P D + C++
Sbjct: 1543 VNTEGSFHCFCSPPLTLDLSQQRCMN 1568
Score = 75.8 bits (178), Expect = 4e-13
Identities = 48/136 (35%), Positives = 62/136 (45%), Gaps = 19/136 (13%)
Query: 160 DVNECEIVD-GVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC 218
D +EC I G+C +G C NT + C C PG+ D K C D DEC D C G C
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGEC 1542
Query: 219 VNTAGSFRCECGHGMELAPDRLSC-------KDIDECSITSGIC----SNGACENQM--- 264
VNT GSF C C + L + C +D+ + I IC +N C +
Sbjct: 1543 VNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGH 1602
Query: 265 -GTY-QCVCDEGYAQS 278
TY +C C +G A S
Sbjct: 1603 RTTYTECCCQDGKAWS 1618
Score = 66.9 bits (156), Expect = 2e-10
Identities = 33/91 (36%), Positives = 47/91 (51%), Gaps = 6/91 (6%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADND---ALCRG 215
+ EC I++G C +G C +TC C G++ D CVD++EC D + LC
Sbjct: 1732 LQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH 1790
Query: 216 GRCVNTAGSFRCEC--GHGMELAPDRLSCKD 244
G C NT GS+RC C G+ E P + K+
Sbjct: 1791 GYCENTEGSYRCHCSPGYVAEAGPPHCTAKE 1821
Score = 65.7 bits (153), Expect = 4e-10
Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSG---ICSNGACENQMGTYQC 269
C GRCV + C+C G +L ++C D++EC +G +C +G CEN G+Y+C
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 270 VCDEGYAQSTVKSH 283
C GY H
Sbjct: 1803 HCSPGYVAEAGPPH 1816
Score = 62.9 bits (146), Expect = 3e-09
Identities = 57/216 (26%), Positives = 79/216 (36%), Gaps = 26/216 (12%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEK-DSKNHTC--VDVNECEIVDGVCGD 173
++VNEC +CG C N+ G F C C E+ D++ C + + GD
Sbjct: 1344 VDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGD 1403
Query: 174 G-------DCHN-TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSF 225
DC++ +G C G C D LC + F
Sbjct: 1404 HAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGATWGDACDLCPS----EDSAEF 1459
Query: 226 RCECGHGMELAP-------DRLSCKDIDECSITS-GICSNGACENQMGTYQCVCDEGYAQ 277
C G P + D DEC I G+C NG C N + Y C+C+ G+
Sbjct: 1460 SEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHY 1519
Query: 278 STVKSHXXXXXXXXXXXXRCQH-SCVNTPGSYHCTC 312
SH C++ CVNT GS+HC C
Sbjct: 1520 DA--SHKKCEDHDECQDLACENGECVNTEGSFHCFC 1553
Score = 59.7 bits (138), Expect = 3e-08
Identities = 22/47 (46%), Positives = 33/47 (70%), Gaps = 1/47 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIA 50
G C+ PL + + +CCCS +GKAWG++ CE CP GT+A++ +C A
Sbjct: 681 GTCTLPLAQRITKQICCCSRVGKAWGSE-CEKCPLPGTEAFREICPA 726
Score = 57.6 bits (133), Expect = 1e-07
Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
+C GY++ + H C D+NEC + G+C D +C NT GS+ C CRPG D CV
Sbjct: 607 ECPQGYKRLNLTH-CQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD 664
Query: 204 DECADNDALC 213
+ LC
Sbjct: 665 KAISMLQGLC 674
Score = 56.4 bits (130), Expect = 3e-07
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECA---GGARPCGGGQCRNTVGSYTC 352
C++ CV Y C C EG+ L A +C D++EC G A C G C NT GSY C
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 353 TCTDGLVPSAAGAKPTCQD 371
C+ G V A T ++
Sbjct: 1803 HCSPGYVAEAGPPHCTAKE 1821
Score = 54.4 bits (125), Expect = 1e-06
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C GYK + + C DI+EC LC+ CVNT GS+ C C G+ L P R C
Sbjct: 608 CPQGYKRLNLTH-CQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDK 665
Query: 247 ECSITSGIC 255
S+ G+C
Sbjct: 666 AISMLQGLC 674
Score = 52.4 bits (120), Expect = 4e-06
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 12/95 (12%)
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC--ANDPT 534
+EC NG C C + C C G++ D + +CVD++EC N P
Sbjct: 1735 EECGILNG-CE-NGRCVRVREGYTCDCFEGFQLDAAHM-------ACVDVNECDDLNGPA 1785
Query: 535 -LCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
LC +G+C NT G Y C C G+ A C K
Sbjct: 1786 VLCVHGYCENTEGSYRCHCSPGYVAEAGPPHCTAK 1820
Score = 47.6 bits (108), Expect = 1e-04
Identities = 35/105 (33%), Positives = 42/105 (40%), Gaps = 21/105 (20%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
+EC G C G+C YTC C +G AA C D++EC DL +
Sbjct: 1735 EEC-GILNGCENGRCVRVREGYTCDCFEGFQLDAAHM--ACVDVNECDDLNGPAV----- 1786
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
LC G C NT GS+ C C GY V P CT
Sbjct: 1787 ------------LCVHGYCENTEGSYRCHCSPGY-VAEAGPPHCT 1818
Score = 47.2 bits (107), Expect = 2e-04
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 4/61 (6%)
Query: 451 CINLPGSFQCRCRDGWRGDGA--TCEDVDECLTNNGGC--HPRATCANTDGSFRCLCDTG 506
C+ + + C C +G++ D A C DV+EC NG C NT+GS+RC C G
Sbjct: 1748 CVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPG 1807
Query: 507 Y 507
Y
Sbjct: 1808 Y 1808
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC----GD 173
++NEC GLC C N G + C C PG D CV ++ G+C G
Sbjct: 622 DINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGP 680
Query: 174 GDC 176
G C
Sbjct: 681 GTC 683
Score = 40.7 bits (91), Expect = 0.013
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
EC G + + C+DI+EC +T G+C + C N G+Y C C G
Sbjct: 607 ECPQGYKRL-NLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPG 651
Score = 40.3 bits (90), Expect = 0.018
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 6/65 (9%)
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGDGAT-CEDVDECLTNNGGCHPRATCANTDGSFRC 501
C PA+ I + Q C G++ T C+D++ECLT G C A C NT GS+ C
Sbjct: 592 CPPRPASPVIE---NGQLECPQGYKRLNLTHCQDINECLTL-GLCKD-AECVNTRGSYLC 646
Query: 502 LCDTG 506
C G
Sbjct: 647 TCRPG 651
Score = 39.9 bits (89), Expect = 0.024
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C +G+ R + C+DI+EC C +C NT GSY CTC GL+
Sbjct: 608 CPQGYK-RLNLTHCQDINECLTLGL-CKDAECVNTRGSYLCTCRPGLM 653
Score = 39.9 bits (89), Expect = 0.024
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Query: 117 MEVNECAAFPG---LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC 158
++VNEC G LC HG C N G + C C PGY ++ C
Sbjct: 1773 VDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 38.7 bits (86), Expect = 0.054
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 1 MTGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
+T CS PL CC GKAW +Q+C CP + ++ Y LC
Sbjct: 1590 VTNDVCSEPLRGHRTTYTECCCQDGKAW-SQQCALCPPRSSEVYAQLC 1636
Score = 37.9 bits (84), Expect = 0.095
Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 6/50 (12%)
Query: 417 QCPDGYSVKPEQGPACTDDDEC-ELGTCDCHPAADCINLPGSFQCRCRDG 465
+CP GY K C D +EC LG C A+C+N GS+ C CR G
Sbjct: 607 ECPQGY--KRLNLTHCQDINECLTLGLCK---DAECVNTRGSYLCTCRPG 651
Score = 36.3 bits (80), Expect = 0.29
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 3/67 (4%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE--LGTCDCHPAADCINLPGSFQ 459
C G C + C C +G+ + AC D +EC+ G C N GS++
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAH-MACVDVNECDDLNGPAVLCVHGYCENTEGSYR 1801
Query: 460 CRCRDGW 466
C C G+
Sbjct: 1802 CHCSPGY 1808
Score = 35.9 bits (79), Expect = 0.38
Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 6/86 (6%)
Query: 268 QCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRD 327
Q C +GY + + +H CVNT GSY CTCR G L D R
Sbjct: 605 QLECPQGYKRLNL-THCQDINECLTLGLCKDAECVNTRGSYLCTCRPG--LMLDPSRSRC 661
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCT 353
+ + A G C ++G TCT
Sbjct: 662 VSDKAISMLQ---GLCYRSLGPGTCT 684
Score = 35.5 bits (78), Expect = 0.51
Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
CS L + +A CCC+ G WG+ C+ CP + + + +C
Sbjct: 1423 CSSVLGRNTTQAECCCTQ-GATWGD-ACDLCPSEDSAEFSEIC 1463
Score = 35.1 bits (77), Expect = 0.67
Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKK 39
G+C+ PL ++ CC ++G WG C PCP +
Sbjct: 561 GQCANPL-LELTTQEDCCGSVGAFWGVTLCAPCPPR 595
Score = 34.3 bits (75), Expect = 1.2
Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
C DI+EC LC++ C NT G Y C C G
Sbjct: 620 CQDINECLT-LGLCKDAECVNTRGSYLCTCRPG 651
>S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growth
factor-beta-binding protein-2 protein.
Length = 1821
Score = 299 bits (734), Expect = 2e-80
Identities = 171/457 (37%), Positives = 229/457 (50%), Gaps = 52/457 (11%)
Query: 119 VNECAA-FPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++ CAA +CG G C NL G+ C C PGY+ C D NEC + D G G C
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNEC-LRDPCKGKGRCI 903
Query: 178 NTEGSFTCHCRPGY--KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
N GS++C C PGY ++ C DI+EC + +C GG+C NT GS+ CEC G +
Sbjct: 904 NRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQGY-I 961
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCV-CDEGYAQSTVKSHXXXXXXXXXXX 294
+ C+DI+EC G C +G C N G+Y C+ C+EGY +S
Sbjct: 962 MVRKGHCQDINECR-HPGTCPDGRCVNSPGSYTCLACEEGYRG---QSGSCVDVNECLTP 1017
Query: 295 XRCQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H C N GS+ C+C +G+ + +D + C+D+DECA A C G C NT GS+ C+
Sbjct: 1018 GVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRA-SCPTGLCLNTEGSFACS 1076
Query: 354 -CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G + G C+D+DECA P +C +G C NT G
Sbjct: 1077 ACENGYWVNEDGT--ACEDLDECA---------------------FPGVCPSGVCTNTAG 1113
Query: 413 SFVCQ-CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDG 470
SF C+ C GY P G +C D DECE C +C N GS+QC C G++ +G
Sbjct: 1114 SFSCKDCDGGYRPSP-LGDSCEDVDECEDPQSSC-LGGECKNTVGSYQCLCPQGFQLANG 1171
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
CEDV+EC+ C P C N+ GSF CLC G+ G SC D+DECA
Sbjct: 1172 TVCEDVNECM-GEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGT-------SCQDVDECA 1223
Query: 531 -NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
DP C GHC NT G + C C+ GF + + C+
Sbjct: 1224 TTDP--CVGGHCVNTEGSFNCLCETGFQPSPESGECV 1258
Score = 264 bits (647), Expect = 6e-70
Identities = 152/393 (38%), Positives = 189/393 (48%), Gaps = 35/393 (8%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++VNEC PG+C HG+C NL G F C C GYE S C DV+EC C G C
Sbjct: 1009 VDVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECAS-RASCPTGLC 1066
Query: 177 HNTEGSFTCH-CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC-ECGHGME 234
NTEGSF C C GY ++ C D+DECA +C G C NTAGSF C +C G
Sbjct: 1067 LNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTNTAGSFSCKDCDGGYR 1125
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+P SC+D+DEC C G C+N +G+YQC+C +G+ +
Sbjct: 1126 PSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEH 1185
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+N+ GS+ C C G+ G SC+D+DECA PC GG C NT GS+ C C
Sbjct: 1186 CAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECAT-TDPCVGGHCVNTEGSFNCLC 1244
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G PS + C DIDEC D DP +CG C N+ GS+
Sbjct: 1245 ETGFQPSPESGE--CVDIDECEDY---------------GDP----VCGTWKCENSPGSY 1283
Query: 415 VC--QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
C C G+ + P C D DEC T C C N GSF+C C G+ G
Sbjct: 1284 RCVLGCQPGFHMAPNGD--CIDIDECANDTM-CGSHGFCDNTDGSFRCLCDQGFEISPSG 1340
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C DV+EC C A C N +GSF CLC
Sbjct: 1341 WDCVDVNECELMLAVC-GAALCENVEGSFLCLC 1372
Score = 210 bits (514), Expect = 8e-54
Identities = 135/456 (29%), Positives = 185/456 (40%), Gaps = 30/456 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC C G C+N +G + C C G++ + C DVNEC + G+C
Sbjct: 1135 DVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGEEHCAPHGECL 1193
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N+ GSF C C PG+ + + C D+DECA D C GG CVNT GSF C C G + +P
Sbjct: 1194 NSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDP-CVGGHCVNTEGSFNCLCETGFQPSP 1252
Query: 238 DRLSCKDIDECS-ITSGICSNGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXX 294
+ C DIDEC +C CEN G+Y+CV C G+ +
Sbjct: 1253 ESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTM 1312
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C NT GS+ C C +G+ + G C D++EC CG C N GS+ C C
Sbjct: 1313 CGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLC 1372
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG-- 412
L A + C+ +S +D + G C + +G
Sbjct: 1373 ASDLEEYDA-QEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQK-GHAPCSSVLGRN 1430
Query: 413 --SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
C C G S + C +D E C I + G+ W
Sbjct: 1431 TTQAECCCTQGAS-WGDACDLCPSEDSAEFSEI-CPSGKGYIPVEGA--------WTFGQ 1480
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
D DEC+ G P C NT + CLC+ G+ D + C D DEC
Sbjct: 1481 TMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKK-------CEDHDECQ 1533
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ CENG C NT G + C C T + C+
Sbjct: 1534 D--LACENGECVNTEGSFHCFCSPPLTLDLSQQRCM 1567
Score = 92.3 bits (219), Expect = 4e-18
Identities = 38/81 (46%), Positives = 53/81 (65%), Gaps = 4/81 (4%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDG---VCGD 173
++ EC G C +GRC + G+TCDCF G++ D+ + CVDVNEC+ ++G +C
Sbjct: 1732 LQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH 1790
Query: 174 GDCHNTEGSFTCHCRPGYKAD 194
G C NTEGS+ CHC PGY A+
Sbjct: 1791 GYCENTEGSYRCHCSPGYVAE 1811
Score = 88.6 bits (210), Expect = 5e-17
Identities = 44/122 (36%), Positives = 65/122 (53%), Gaps = 6/122 (4%)
Query: 117 MEVNECAAFPG-LCGHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGD 173
++++EC + +CG +C N G + C C PG+ + N C+D++EC D +CG
Sbjct: 1258 VDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHM-APNGDCIDIDECAN-DTMCGS 1315
Query: 174 -GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
G C NT+GSF C C G++ CVD++EC A+C C N GSF C C
Sbjct: 1316 HGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASD 1375
Query: 233 ME 234
+E
Sbjct: 1376 LE 1377
Score = 81.8 bits (193), Expect = 6e-15
Identities = 36/86 (41%), Positives = 51/86 (59%), Gaps = 3/86 (3%)
Query: 118 EVNECAAF-PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+ +EC F PGLC +GRC N + G+ C C PG+ D+ + C D +EC+ D C +G+C
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ--DLACENGEC 1542
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD 202
NTEGSF C C P D + C++
Sbjct: 1543 VNTEGSFHCFCSPPLTLDLSQQRCMN 1568
Score = 75.8 bits (178), Expect = 4e-13
Identities = 48/136 (35%), Positives = 62/136 (45%), Gaps = 19/136 (13%)
Query: 160 DVNECEIVD-GVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC 218
D +EC I G+C +G C NT + C C PG+ D K C D DEC D C G C
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGEC 1542
Query: 219 VNTAGSFRCECGHGMELAPDRLSC-------KDIDECSITSGIC----SNGACENQM--- 264
VNT GSF C C + L + C +D+ + I IC +N C +
Sbjct: 1543 VNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGH 1602
Query: 265 -GTY-QCVCDEGYAQS 278
TY +C C +G A S
Sbjct: 1603 RTTYTECCCQDGEAWS 1618
Score = 66.9 bits (156), Expect = 2e-10
Identities = 33/91 (36%), Positives = 47/91 (51%), Gaps = 6/91 (6%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADND---ALCRG 215
+ EC I++G C +G C +TC C G++ D CVD++EC D + LC
Sbjct: 1732 LQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH 1790
Query: 216 GRCVNTAGSFRCEC--GHGMELAPDRLSCKD 244
G C NT GS+RC C G+ E P + K+
Sbjct: 1791 GYCENTEGSYRCHCSPGYVAEAGPPHCTAKE 1821
Score = 65.7 bits (153), Expect = 4e-10
Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSG---ICSNGACENQMGTYQC 269
C GRCV + C+C G +L ++C D++EC +G +C +G CEN G+Y+C
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 270 VCDEGYAQSTVKSH 283
C GY H
Sbjct: 1803 HCSPGYVAEAGPPH 1816
Score = 63.3 bits (147), Expect = 2e-09
Identities = 57/216 (26%), Positives = 79/216 (36%), Gaps = 26/216 (12%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEK-DSKNHTC--VDVNECEIVDGVCGD 173
++VNEC +CG C N+ G F C C E+ D++ C + + GD
Sbjct: 1344 VDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGD 1403
Query: 174 G-------DCHN-TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSF 225
DC++ +G C G C D LC + F
Sbjct: 1404 HAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPS----EDSAEF 1459
Query: 226 RCECGHGMELAP-------DRLSCKDIDECSITS-GICSNGACENQMGTYQCVCDEGYAQ 277
C G P + D DEC I G+C NG C N + Y C+C+ G+
Sbjct: 1460 SEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHY 1519
Query: 278 STVKSHXXXXXXXXXXXXRCQH-SCVNTPGSYHCTC 312
SH C++ CVNT GS+HC C
Sbjct: 1520 DA--SHKKCEDHDECQDLACENGECVNTEGSFHCFC 1553
Score = 59.7 bits (138), Expect = 3e-08
Identities = 22/47 (46%), Positives = 33/47 (70%), Gaps = 1/47 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIA 50
G C+ PL + + +CCCS +GKAWG++ CE CP GT+A++ +C A
Sbjct: 681 GTCTLPLAQRITKQICCCSRVGKAWGSE-CEKCPLPGTEAFREICPA 726
Score = 57.6 bits (133), Expect = 1e-07
Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
+C GY++ + H C D+NEC + G+C D +C NT GS+ C CRPG D CV
Sbjct: 607 ECPQGYKRLNLTH-CQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD 664
Query: 204 DECADNDALC 213
+ LC
Sbjct: 665 KAISMLQGLC 674
Score = 56.4 bits (130), Expect = 3e-07
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECA---GGARPCGGGQCRNTVGSYTC 352
C++ CV Y C C EG+ L A +C D++EC G A C G C NT GSY C
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 353 TCTDGLVPSAAGAKPTCQD 371
C+ G V A T ++
Sbjct: 1803 HCSPGYVAEAGPPHCTAKE 1821
Score = 54.4 bits (125), Expect = 1e-06
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C GYK + + C DI+EC LC+ CVNT GS+ C C G+ L P R C
Sbjct: 608 CPQGYKRLNLTH-CQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDK 665
Query: 247 ECSITSGIC 255
S+ G+C
Sbjct: 666 AISMLQGLC 674
Score = 52.4 bits (120), Expect = 4e-06
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 12/95 (12%)
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC--ANDPT 534
+EC NG C C + C C G++ D + +CVD++EC N P
Sbjct: 1735 EECGILNG-CE-NGRCVRVREGYTCDCFEGFQLDAAHM-------ACVDVNECDDLNGPA 1785
Query: 535 -LCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
LC +G+C NT G Y C C G+ A C K
Sbjct: 1786 VLCVHGYCENTEGSYRCHCSPGYVAEAGPPHCTAK 1820
Score = 47.6 bits (108), Expect = 1e-04
Identities = 35/105 (33%), Positives = 42/105 (40%), Gaps = 21/105 (20%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
+EC G C G+C YTC C +G AA C D++EC DL +
Sbjct: 1735 EEC-GILNGCENGRCVRVREGYTCDCFEGFQLDAAHM--ACVDVNECDDLNGPAV----- 1786
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
LC G C NT GS+ C C GY V P CT
Sbjct: 1787 ------------LCVHGYCENTEGSYRCHCSPGY-VAEAGPPHCT 1818
Score = 47.2 bits (107), Expect = 2e-04
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 4/61 (6%)
Query: 451 CINLPGSFQCRCRDGWRGDGA--TCEDVDECLTNNGGC--HPRATCANTDGSFRCLCDTG 506
C+ + + C C +G++ D A C DV+EC NG C NT+GS+RC C G
Sbjct: 1748 CVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPG 1807
Query: 507 Y 507
Y
Sbjct: 1808 Y 1808
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC----GD 173
++NEC GLC C N G + C C PG D CV ++ G+C G
Sbjct: 622 DINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGP 680
Query: 174 GDC 176
G C
Sbjct: 681 GTC 683
Score = 40.7 bits (91), Expect = 0.013
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
EC G + + C+DI+EC +T G+C + C N G+Y C C G
Sbjct: 607 ECPQGYKRL-NLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPG 651
Score = 40.3 bits (90), Expect = 0.018
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 6/65 (9%)
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGDGAT-CEDVDECLTNNGGCHPRATCANTDGSFRC 501
C PA+ I + Q C G++ T C+D++ECLT G C A C NT GS+ C
Sbjct: 592 CPPRPASPVIE---NGQLECPQGYKRLNLTHCQDINECLTL-GLCKD-AECVNTRGSYLC 646
Query: 502 LCDTG 506
C G
Sbjct: 647 TCRPG 651
Score = 39.9 bits (89), Expect = 0.024
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C +G+ R + C+DI+EC C +C NT GSY CTC GL+
Sbjct: 608 CPQGYK-RLNLTHCQDINECLTLGL-CKDAECVNTRGSYLCTCRPGLM 653
Score = 39.9 bits (89), Expect = 0.024
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Query: 117 MEVNECAAFPG---LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC 158
++VNEC G LC HG C N G + C C PGY ++ C
Sbjct: 1773 VDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 37.9 bits (84), Expect = 0.095
Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 6/50 (12%)
Query: 417 QCPDGYSVKPEQGPACTDDDEC-ELGTCDCHPAADCINLPGSFQCRCRDG 465
+CP GY K C D +EC LG C A+C+N GS+ C CR G
Sbjct: 607 ECPQGY--KRLNLTHCQDINECLTLGLCK---DAECVNTRGSYLCTCRPG 651
Score = 37.1 bits (82), Expect = 0.17
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 1 MTGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
+T CS PL CC G+AW +Q+C CP + ++ Y LC
Sbjct: 1590 VTNDVCSEPLRGHRTTYTECCCQDGEAW-SQQCALCPPRSSEVYAQLC 1636
Score = 36.3 bits (80), Expect = 0.29
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 3/67 (4%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE--LGTCDCHPAADCINLPGSFQ 459
C G C + C C +G+ + AC D +EC+ G C N GS++
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAH-MACVDVNECDDLNGPAVLCVHGYCENTEGSYR 1801
Query: 460 CRCRDGW 466
C C G+
Sbjct: 1802 CHCSPGY 1808
Score = 35.9 bits (79), Expect = 0.38
Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 6/86 (6%)
Query: 268 QCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRD 327
Q C +GY + + +H CVNT GSY CTCR G L D R
Sbjct: 605 QLECPQGYKRLNL-THCQDINECLTLGLCKDAECVNTRGSYLCTCRPG--LMLDPSRSRC 661
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCT 353
+ + A G C ++G TCT
Sbjct: 662 VSDKAISMLQ---GLCYRSLGPGTCT 684
Score = 35.9 bits (79), Expect = 0.38
Identities = 14/43 (32%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
CS L + +A CCC+ G +WG+ C+ CP + + + +C
Sbjct: 1423 CSSVLGRNTTQAECCCTQ-GASWGD-ACDLCPSEDSAEFSEIC 1463
Score = 35.1 bits (77), Expect = 0.67
Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKK 39
G+C+ PL ++ CC ++G WG C PCP +
Sbjct: 561 GQCANPL-LELTTQEDCCGSVGAFWGVTLCAPCPPR 595
Score = 34.3 bits (75), Expect = 1.2
Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
C DI+EC LC++ C NT G Y C C G
Sbjct: 620 CQDINECLT-LGLCKDAECVNTRGSYLCTCRPG 651
>BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming growth
factor beta binding protein 2 protein.
Length = 1821
Score = 299 bits (734), Expect = 2e-80
Identities = 171/457 (37%), Positives = 229/457 (50%), Gaps = 52/457 (11%)
Query: 119 VNECAA-FPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++ CAA +CG G C NL G+ C C PGY+ C D NEC + D G G C
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNEC-LRDPCKGKGRCI 903
Query: 178 NTEGSFTCHCRPGY--KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
N GS++C C PGY ++ C DI+EC + +C GG+C NT GS+ CEC G +
Sbjct: 904 NRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQGY-I 961
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCV-CDEGYAQSTVKSHXXXXXXXXXXX 294
+ C+DI+EC G C +G C N G+Y C+ C+EGY +S
Sbjct: 962 MVRKGHCQDINECR-HPGTCPDGRCVNSPGSYTCLACEEGYRG---QSGSCVDVNECLTP 1017
Query: 295 XRCQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H C N GS+ C+C +G+ + +D + C+D+DECA A C G C NT GS+ C+
Sbjct: 1018 GVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRA-SCPTGLCLNTEGSFACS 1076
Query: 354 -CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G + G C+D+DECA P +C +G C NT G
Sbjct: 1077 ACENGYWVNEDGT--ACEDLDECA---------------------FPGVCPSGVCTNTAG 1113
Query: 413 SFVCQ-CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDG 470
SF C+ C GY P G +C D DECE C +C N GS+QC C G++ +G
Sbjct: 1114 SFSCKDCDGGYRPSP-LGDSCEDVDECEDPQSSC-LGGECKNTVGSYQCLCPQGFQLANG 1171
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
CEDV+EC+ C P C N+ GSF CLC G+ G SC D+DECA
Sbjct: 1172 TVCEDVNECM-GEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGT-------SCQDVDECA 1223
Query: 531 -NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
DP C GHC NT G + C C+ GF + + C+
Sbjct: 1224 TTDP--CVGGHCVNTEGSFNCLCETGFQPSPESGECV 1258
Score = 264 bits (647), Expect = 6e-70
Identities = 152/393 (38%), Positives = 189/393 (48%), Gaps = 35/393 (8%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++VNEC PG+C HG+C NL G F C C GYE S C DV+EC C G C
Sbjct: 1009 VDVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECAS-RASCPTGLC 1066
Query: 177 HNTEGSFTCH-CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC-ECGHGME 234
NTEGSF C C GY ++ C D+DECA +C G C NTAGSF C +C G
Sbjct: 1067 LNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTNTAGSFSCKDCDGGYR 1125
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+P SC+D+DEC C G C+N +G+YQC+C +G+ +
Sbjct: 1126 PSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEH 1185
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+N+ GS+ C C G+ G SC+D+DECA PC GG C NT GS+ C C
Sbjct: 1186 CAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECAT-TDPCVGGHCVNTEGSFNCLC 1244
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G PS + C DIDEC D DP +CG C N+ GS+
Sbjct: 1245 ETGFQPSPESGE--CVDIDECEDY---------------GDP----VCGTWKCENSPGSY 1283
Query: 415 VC--QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
C C G+ + P C D DEC T C C N GSF+C C G+ G
Sbjct: 1284 RCVLGCQPGFHMAPNGD--CIDIDECANDTM-CGSHGFCDNTDGSFRCLCDQGFEISPSG 1340
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C DV+EC C A C N +GSF CLC
Sbjct: 1341 WDCVDVNECELMLAVC-GAALCENVEGSFLCLC 1372
Score = 210 bits (514), Expect = 8e-54
Identities = 135/456 (29%), Positives = 185/456 (40%), Gaps = 30/456 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC C G C+N +G + C C G++ + C DVNEC + G+C
Sbjct: 1135 DVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGEEHCAPHGECL 1193
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N+ GSF C C PG+ + + C D+DECA D C GG CVNT GSF C C G + +P
Sbjct: 1194 NSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDP-CVGGHCVNTEGSFNCLCETGFQPSP 1252
Query: 238 DRLSCKDIDECS-ITSGICSNGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXX 294
+ C DIDEC +C CEN G+Y+CV C G+ +
Sbjct: 1253 ESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTM 1312
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C NT GS+ C C +G+ + G C D++EC CG C N GS+ C C
Sbjct: 1313 CGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLC 1372
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG-- 412
L A + C+ +S +D + G C + +G
Sbjct: 1373 ASDLEEYDA-QEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQK-GHAPCSSVLGRN 1430
Query: 413 --SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
C C G S + C +D E C I + G+ W
Sbjct: 1431 TTQAECCCTQGAS-WGDACDLCPSEDSAEFSEI-CPSGKGYIPVEGA--------WTFGQ 1480
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
D DEC+ G P C NT + CLC+ G+ D + C D DEC
Sbjct: 1481 TMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKK-------CEDHDECQ 1533
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ CENG C NT G + C C T + C+
Sbjct: 1534 D--LACENGECVNTEGSFHCFCSPPLTLDLSQQRCM 1567
Score = 92.3 bits (219), Expect = 4e-18
Identities = 38/81 (46%), Positives = 53/81 (65%), Gaps = 4/81 (4%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDG---VCGD 173
++ EC G C +GRC + G+TCDCF G++ D+ + CVDVNEC+ ++G +C
Sbjct: 1732 LQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH 1790
Query: 174 GDCHNTEGSFTCHCRPGYKAD 194
G C NTEGS+ CHC PGY A+
Sbjct: 1791 GYCENTEGSYRCHCSPGYVAE 1811
Score = 88.6 bits (210), Expect = 5e-17
Identities = 44/122 (36%), Positives = 65/122 (53%), Gaps = 6/122 (4%)
Query: 117 MEVNECAAFPG-LCGHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGD 173
++++EC + +CG +C N G + C C PG+ + N C+D++EC D +CG
Sbjct: 1258 VDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHM-APNGDCIDIDECAN-DTMCGS 1315
Query: 174 -GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
G C NT+GSF C C G++ CVD++EC A+C C N GSF C C
Sbjct: 1316 HGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASD 1375
Query: 233 ME 234
+E
Sbjct: 1376 LE 1377
Score = 81.8 bits (193), Expect = 6e-15
Identities = 36/86 (41%), Positives = 51/86 (59%), Gaps = 3/86 (3%)
Query: 118 EVNECAAF-PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+ +EC F PGLC +GRC N + G+ C C PG+ D+ + C D +EC+ D C +G+C
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ--DLACENGEC 1542
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD 202
NTEGSF C C P D + C++
Sbjct: 1543 VNTEGSFHCFCSPPLTLDLSQQRCMN 1568
Score = 75.8 bits (178), Expect = 4e-13
Identities = 48/136 (35%), Positives = 62/136 (45%), Gaps = 19/136 (13%)
Query: 160 DVNECEIVD-GVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC 218
D +EC I G+C +G C NT + C C PG+ D K C D DEC D C G C
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGEC 1542
Query: 219 VNTAGSFRCECGHGMELAPDRLSC-------KDIDECSITSGIC----SNGACENQM--- 264
VNT GSF C C + L + C +D+ + I IC +N C +
Sbjct: 1543 VNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGH 1602
Query: 265 -GTY-QCVCDEGYAQS 278
TY +C C +G A S
Sbjct: 1603 RTTYTECCCQDGEAWS 1618
Score = 66.9 bits (156), Expect = 2e-10
Identities = 33/91 (36%), Positives = 47/91 (51%), Gaps = 6/91 (6%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADND---ALCRG 215
+ EC I++G C +G C +TC C G++ D CVD++EC D + LC
Sbjct: 1732 LQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH 1790
Query: 216 GRCVNTAGSFRCEC--GHGMELAPDRLSCKD 244
G C NT GS+RC C G+ E P + K+
Sbjct: 1791 GYCENTEGSYRCHCSPGYVAEAGPPHCTAKE 1821
Score = 65.7 bits (153), Expect = 4e-10
Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSG---ICSNGACENQMGTYQC 269
C GRCV + C+C G +L ++C D++EC +G +C +G CEN G+Y+C
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 270 VCDEGYAQSTVKSH 283
C GY H
Sbjct: 1803 HCSPGYVAEAGPPH 1816
Score = 63.3 bits (147), Expect = 2e-09
Identities = 57/216 (26%), Positives = 79/216 (36%), Gaps = 26/216 (12%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEK-DSKNHTC--VDVNECEIVDGVCGD 173
++VNEC +CG C N+ G F C C E+ D++ C + + GD
Sbjct: 1344 VDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGD 1403
Query: 174 G-------DCHN-TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSF 225
DC++ +G C G C D LC + F
Sbjct: 1404 HAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPS----EDSAEF 1459
Query: 226 RCECGHGMELAP-------DRLSCKDIDECSITS-GICSNGACENQMGTYQCVCDEGYAQ 277
C G P + D DEC I G+C NG C N + Y C+C+ G+
Sbjct: 1460 SEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHY 1519
Query: 278 STVKSHXXXXXXXXXXXXRCQH-SCVNTPGSYHCTC 312
SH C++ CVNT GS+HC C
Sbjct: 1520 DA--SHKKCEDHDECQDLACENGECVNTEGSFHCFC 1553
Score = 59.7 bits (138), Expect = 3e-08
Identities = 22/47 (46%), Positives = 33/47 (70%), Gaps = 1/47 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIA 50
G C+ PL + + +CCCS +GKAWG++ CE CP GT+A++ +C A
Sbjct: 681 GTCTLPLAQRITKQICCCSRVGKAWGSE-CEKCPLPGTEAFREICPA 726
Score = 57.6 bits (133), Expect = 1e-07
Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
+C GY++ + H C D+NEC + G+C D +C NT GS+ C CRPG D CV
Sbjct: 607 ECPQGYKRLNLTH-CQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD 664
Query: 204 DECADNDALC 213
+ LC
Sbjct: 665 KAISMLQGLC 674
Score = 56.4 bits (130), Expect = 3e-07
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECA---GGARPCGGGQCRNTVGSYTC 352
C++ CV Y C C EG+ L A +C D++EC G A C G C NT GSY C
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 353 TCTDGLVPSAAGAKPTCQD 371
C+ G V A T ++
Sbjct: 1803 HCSPGYVAEAGPPHCTAKE 1821
Score = 54.4 bits (125), Expect = 1e-06
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C GYK + + C DI+EC LC+ CVNT GS+ C C G+ L P R C
Sbjct: 608 CPQGYKRLNLTH-CQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDK 665
Query: 247 ECSITSGIC 255
S+ G+C
Sbjct: 666 AISMLQGLC 674
Score = 52.4 bits (120), Expect = 4e-06
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 12/95 (12%)
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC--ANDPT 534
+EC NG C C + C C G++ D + +CVD++EC N P
Sbjct: 1735 EECGILNG-CE-NGRCVRVREGYTCDCFEGFQLDAAHM-------ACVDVNECDDLNGPA 1785
Query: 535 -LCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
LC +G+C NT G Y C C G+ A C K
Sbjct: 1786 VLCVHGYCENTEGSYRCHCSPGYVAEAGPPHCTAK 1820
Score = 47.6 bits (108), Expect = 1e-04
Identities = 35/105 (33%), Positives = 42/105 (40%), Gaps = 21/105 (20%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
+EC G C G+C YTC C +G AA C D++EC DL +
Sbjct: 1735 EEC-GILNGCENGRCVRVREGYTCDCFEGFQLDAAHM--ACVDVNECDDLNGPAV----- 1786
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
LC G C NT GS+ C C GY V P CT
Sbjct: 1787 ------------LCVHGYCENTEGSYRCHCSPGY-VAEAGPPHCT 1818
Score = 47.2 bits (107), Expect = 2e-04
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 4/61 (6%)
Query: 451 CINLPGSFQCRCRDGWRGDGA--TCEDVDECLTNNGGC--HPRATCANTDGSFRCLCDTG 506
C+ + + C C +G++ D A C DV+EC NG C NT+GS+RC C G
Sbjct: 1748 CVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPG 1807
Query: 507 Y 507
Y
Sbjct: 1808 Y 1808
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC----GD 173
++NEC GLC C N G + C C PG D CV ++ G+C G
Sbjct: 622 DINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGP 680
Query: 174 GDC 176
G C
Sbjct: 681 GTC 683
Score = 40.7 bits (91), Expect = 0.013
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
EC G + + C+DI+EC +T G+C + C N G+Y C C G
Sbjct: 607 ECPQGYKRL-NLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPG 651
Score = 40.3 bits (90), Expect = 0.018
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 6/65 (9%)
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGDGAT-CEDVDECLTNNGGCHPRATCANTDGSFRC 501
C PA+ I + Q C G++ T C+D++ECLT G C A C NT GS+ C
Sbjct: 592 CPPRPASPVIE---NGQLECPQGYKRLNLTHCQDINECLTL-GLCKD-AECVNTRGSYLC 646
Query: 502 LCDTG 506
C G
Sbjct: 647 TCRPG 651
Score = 39.9 bits (89), Expect = 0.024
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C +G+ R + C+DI+EC C +C NT GSY CTC GL+
Sbjct: 608 CPQGYK-RLNLTHCQDINECLTLGL-CKDAECVNTRGSYLCTCRPGLM 653
Score = 39.9 bits (89), Expect = 0.024
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Query: 117 MEVNECAAFPG---LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC 158
++VNEC G LC HG C N G + C C PGY ++ C
Sbjct: 1773 VDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 37.9 bits (84), Expect = 0.095
Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 6/50 (12%)
Query: 417 QCPDGYSVKPEQGPACTDDDEC-ELGTCDCHPAADCINLPGSFQCRCRDG 465
+CP GY K C D +EC LG C A+C+N GS+ C CR G
Sbjct: 607 ECPQGY--KRLNLTHCQDINECLTLGLCK---DAECVNTRGSYLCTCRPG 651
Score = 37.1 bits (82), Expect = 0.17
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 1 MTGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
+T CS PL CC G+AW +Q+C CP + ++ Y LC
Sbjct: 1590 VTNDVCSEPLRGHRTTYTECCCQDGEAW-SQQCALCPPRSSEVYAQLC 1636
Score = 36.3 bits (80), Expect = 0.29
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 3/67 (4%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE--LGTCDCHPAADCINLPGSFQ 459
C G C + C C +G+ + AC D +EC+ G C N GS++
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAH-MACVDVNECDDLNGPAVLCVHGYCENTEGSYR 1801
Query: 460 CRCRDGW 466
C C G+
Sbjct: 1802 CHCSPGY 1808
Score = 35.9 bits (79), Expect = 0.38
Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 6/86 (6%)
Query: 268 QCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRD 327
Q C +GY + + +H CVNT GSY CTCR G L D R
Sbjct: 605 QLECPQGYKRLNL-THCQDINECLTLGLCKDAECVNTRGSYLCTCRPG--LMLDPSRSRC 661
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCT 353
+ + A G C ++G TCT
Sbjct: 662 VSDKAISMLQ---GLCYRSLGPGTCT 684
Score = 35.9 bits (79), Expect = 0.38
Identities = 14/43 (32%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
CS L + +A CCC+ G +WG+ C+ CP + + + +C
Sbjct: 1423 CSSVLGRNTTQAECCCTQ-GASWGD-ACDLCPSEDSAEFSEIC 1463
Score = 35.1 bits (77), Expect = 0.67
Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKK 39
G+C+ PL ++ CC ++G WG C PCP +
Sbjct: 561 GQCANPL-LELTTQEDCCGSVGAFWGVTLCAPCPPR 595
Score = 34.3 bits (75), Expect = 1.2
Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
C DI+EC LC++ C NT G Y C C G
Sbjct: 620 CQDINECLT-LGLCKDAECVNTRGSYLCTCRPG 651
>AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming growth
factor beta binding protein 2 variant protein.
Length = 1700
Score = 299 bits (734), Expect = 2e-80
Identities = 171/457 (37%), Positives = 229/457 (50%), Gaps = 52/457 (11%)
Query: 119 VNECAA-FPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++ CAA +CG G C NL G+ C C PGY+ C D NEC + D G G C
Sbjct: 724 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNEC-LRDPCKGKGRCI 782
Query: 178 NTEGSFTCHCRPGY--KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
N GS++C C PGY ++ C DI+EC + +C GG+C NT GS+ CEC G +
Sbjct: 783 NRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQGY-I 840
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCV-CDEGYAQSTVKSHXXXXXXXXXXX 294
+ C+DI+EC G C +G C N G+Y C+ C+EGY +S
Sbjct: 841 MVRKGHCQDINECR-HPGTCPDGRCVNSPGSYTCLACEEGYRG---QSGSCVDVNECLTP 896
Query: 295 XRCQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H C N GS+ C+C +G+ + +D + C+D+DECA A C G C NT GS+ C+
Sbjct: 897 GVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRA-SCPTGLCLNTEGSFACS 955
Query: 354 -CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G + G C+D+DECA P +C +G C NT G
Sbjct: 956 ACENGYWVNEDGT--ACEDLDECA---------------------FPGVCPSGVCTNTAG 992
Query: 413 SFVCQ-CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDG 470
SF C+ C GY P G +C D DECE C +C N GS+QC C G++ +G
Sbjct: 993 SFSCKDCDGGYRPSP-LGDSCEDVDECEDPQSSC-LGGECKNTVGSYQCLCPQGFQLANG 1050
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
CEDV+EC+ C P C N+ GSF CLC G+ G SC D+DECA
Sbjct: 1051 TVCEDVNECM-GEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGT-------SCQDVDECA 1102
Query: 531 -NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
DP C GHC NT G + C C+ GF + + C+
Sbjct: 1103 TTDP--CVGGHCVNTEGSFNCLCETGFQPSPESGECV 1137
Score = 264 bits (647), Expect = 6e-70
Identities = 152/393 (38%), Positives = 189/393 (48%), Gaps = 35/393 (8%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++VNEC PG+C HG+C NL G F C C GYE S C DV+EC C G C
Sbjct: 888 VDVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECAS-RASCPTGLC 945
Query: 177 HNTEGSFTCH-CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC-ECGHGME 234
NTEGSF C C GY ++ C D+DECA +C G C NTAGSF C +C G
Sbjct: 946 LNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTNTAGSFSCKDCDGGYR 1004
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+P SC+D+DEC C G C+N +G+YQC+C +G+ +
Sbjct: 1005 PSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEH 1064
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+N+ GS+ C C G+ G SC+D+DECA PC GG C NT GS+ C C
Sbjct: 1065 CAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECAT-TDPCVGGHCVNTEGSFNCLC 1123
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G PS + C DIDEC D DP +CG C N+ GS+
Sbjct: 1124 ETGFQPSPESGE--CVDIDECEDY---------------GDP----VCGTWKCENSPGSY 1162
Query: 415 VC--QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
C C G+ + P C D DEC T C C N GSF+C C G+ G
Sbjct: 1163 RCVLGCQPGFHMAPNGD--CIDIDECANDTM-CGSHGFCDNTDGSFRCLCDQGFEISPSG 1219
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C DV+EC C A C N +GSF CLC
Sbjct: 1220 WDCVDVNECELMLAVC-GAALCENVEGSFLCLC 1251
Score = 210 bits (514), Expect = 8e-54
Identities = 135/456 (29%), Positives = 185/456 (40%), Gaps = 30/456 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC C G C+N +G + C C G++ + C DVNEC + G+C
Sbjct: 1014 DVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGEEHCAPHGECL 1072
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N+ GSF C C PG+ + + C D+DECA D C GG CVNT GSF C C G + +P
Sbjct: 1073 NSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDP-CVGGHCVNTEGSFNCLCETGFQPSP 1131
Query: 238 DRLSCKDIDECS-ITSGICSNGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXX 294
+ C DIDEC +C CEN G+Y+CV C G+ +
Sbjct: 1132 ESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTM 1191
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C NT GS+ C C +G+ + G C D++EC CG C N GS+ C C
Sbjct: 1192 CGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLC 1251
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG-- 412
L A + C+ +S +D + G C + +G
Sbjct: 1252 ASDLEEYDA-QEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQK-GHAPCSSVLGRN 1309
Query: 413 --SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
C C G S + C +D E C I + G+ W
Sbjct: 1310 TTQAECCCTQGAS-WGDACDLCPSEDSAEFSEI-CPSGKGYIPVEGA--------WTFGQ 1359
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
D DEC+ G P C NT + CLC+ G+ D + C D DEC
Sbjct: 1360 TMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKK-------CEDHDECQ 1412
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+ CENG C NT G + C C T + C+
Sbjct: 1413 D--LACENGECVNTEGSFHCFCSPPLTLDLSQQRCM 1446
Score = 92.3 bits (219), Expect = 4e-18
Identities = 38/81 (46%), Positives = 53/81 (65%), Gaps = 4/81 (4%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDG---VCGD 173
++ EC G C +GRC + G+TCDCF G++ D+ + CVDVNEC+ ++G +C
Sbjct: 1611 LQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH 1669
Query: 174 GDCHNTEGSFTCHCRPGYKAD 194
G C NTEGS+ CHC PGY A+
Sbjct: 1670 GYCENTEGSYRCHCSPGYVAE 1690
Score = 88.6 bits (210), Expect = 5e-17
Identities = 44/122 (36%), Positives = 65/122 (53%), Gaps = 6/122 (4%)
Query: 117 MEVNECAAFPG-LCGHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGD 173
++++EC + +CG +C N G + C C PG+ + N C+D++EC D +CG
Sbjct: 1137 VDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHM-APNGDCIDIDECAN-DTMCGS 1194
Query: 174 -GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
G C NT+GSF C C G++ CVD++EC A+C C N GSF C C
Sbjct: 1195 HGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASD 1254
Query: 233 ME 234
+E
Sbjct: 1255 LE 1256
Score = 81.8 bits (193), Expect = 6e-15
Identities = 36/86 (41%), Positives = 51/86 (59%), Gaps = 3/86 (3%)
Query: 118 EVNECAAF-PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+ +EC F PGLC +GRC N + G+ C C PG+ D+ + C D +EC+ D C +G+C
Sbjct: 1364 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ--DLACENGEC 1421
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD 202
NTEGSF C C P D + C++
Sbjct: 1422 VNTEGSFHCFCSPPLTLDLSQQRCMN 1447
Score = 75.8 bits (178), Expect = 4e-13
Identities = 48/136 (35%), Positives = 62/136 (45%), Gaps = 19/136 (13%)
Query: 160 DVNECEIVD-GVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC 218
D +EC I G+C +G C NT + C C PG+ D K C D DEC D C G C
Sbjct: 1364 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGEC 1421
Query: 219 VNTAGSFRCECGHGMELAPDRLSC-------KDIDECSITSGIC----SNGACENQM--- 264
VNT GSF C C + L + C +D+ + I IC +N C +
Sbjct: 1422 VNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKATNDVCSEPLRGH 1481
Query: 265 -GTY-QCVCDEGYAQS 278
TY +C C +G A S
Sbjct: 1482 RTTYTECCCQDGEAWS 1497
Score = 66.9 bits (156), Expect = 2e-10
Identities = 33/91 (36%), Positives = 47/91 (51%), Gaps = 6/91 (6%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADND---ALCRG 215
+ EC I++G C +G C +TC C G++ D CVD++EC D + LC
Sbjct: 1611 LQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH 1669
Query: 216 GRCVNTAGSFRCEC--GHGMELAPDRLSCKD 244
G C NT GS+RC C G+ E P + K+
Sbjct: 1670 GYCENTEGSYRCHCSPGYVAEAGPPHCTAKE 1700
Score = 65.7 bits (153), Expect = 4e-10
Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSG---ICSNGACENQMGTYQC 269
C GRCV + C+C G +L ++C D++EC +G +C +G CEN G+Y+C
Sbjct: 1622 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1681
Query: 270 VCDEGYAQSTVKSH 283
C GY H
Sbjct: 1682 HCSPGYVAEAGPPH 1695
Score = 63.3 bits (147), Expect = 2e-09
Identities = 57/216 (26%), Positives = 79/216 (36%), Gaps = 26/216 (12%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEK-DSKNHTC--VDVNECEIVDGVCGD 173
++VNEC +CG C N+ G F C C E+ D++ C + + GD
Sbjct: 1223 VDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGD 1282
Query: 174 G-------DCHN-TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSF 225
DC++ +G C G C D LC + F
Sbjct: 1283 HAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPS----EDSAEF 1338
Query: 226 RCECGHGMELAP-------DRLSCKDIDECSITS-GICSNGACENQMGTYQCVCDEGYAQ 277
C G P + D DEC I G+C NG C N + Y C+C+ G+
Sbjct: 1339 SEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHY 1398
Query: 278 STVKSHXXXXXXXXXXXXRCQH-SCVNTPGSYHCTC 312
SH C++ CVNT GS+HC C
Sbjct: 1399 DA--SHKKCEDHDECQDLACENGECVNTEGSFHCFC 1432
Score = 59.7 bits (138), Expect = 3e-08
Identities = 22/47 (46%), Positives = 33/47 (70%), Gaps = 1/47 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIA 50
G C+ PL + + +CCCS +GKAWG++ CE CP GT+A++ +C A
Sbjct: 560 GTCTLPLAQRITKQICCCSRVGKAWGSE-CEKCPLPGTEAFREICPA 605
Score = 57.6 bits (133), Expect = 1e-07
Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
+C GY++ + H C D+NEC + G+C D +C NT GS+ C CRPG D CV
Sbjct: 486 ECPQGYKRLNLTH-CQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD 543
Query: 204 DECADNDALC 213
+ LC
Sbjct: 544 KAISMLQGLC 553
Score = 56.4 bits (130), Expect = 3e-07
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECA---GGARPCGGGQCRNTVGSYTC 352
C++ CV Y C C EG+ L A +C D++EC G A C G C NT GSY C
Sbjct: 1622 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1681
Query: 353 TCTDGLVPSAAGAKPTCQD 371
C+ G V A T ++
Sbjct: 1682 HCSPGYVAEAGPPHCTAKE 1700
Score = 54.4 bits (125), Expect = 1e-06
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C GYK + + C DI+EC LC+ CVNT GS+ C C G+ L P R C
Sbjct: 487 CPQGYKRLNLTH-CQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDK 544
Query: 247 ECSITSGIC 255
S+ G+C
Sbjct: 545 AISMLQGLC 553
Score = 52.4 bits (120), Expect = 4e-06
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 12/95 (12%)
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC--ANDPT 534
+EC NG C C + C C G++ D + +CVD++EC N P
Sbjct: 1614 EECGILNG-CE-NGRCVRVREGYTCDCFEGFQLDAAHM-------ACVDVNECDDLNGPA 1664
Query: 535 -LCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
LC +G+C NT G Y C C G+ A C K
Sbjct: 1665 VLCVHGYCENTEGSYRCHCSPGYVAEAGPPHCTAK 1699
Score = 47.6 bits (108), Expect = 1e-04
Identities = 35/105 (33%), Positives = 42/105 (40%), Gaps = 21/105 (20%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
+EC G C G+C YTC C +G AA C D++EC DL +
Sbjct: 1614 EEC-GILNGCENGRCVRVREGYTCDCFEGFQLDAAHM--ACVDVNECDDLNGPAV----- 1665
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
LC G C NT GS+ C C GY V P CT
Sbjct: 1666 ------------LCVHGYCENTEGSYRCHCSPGY-VAEAGPPHCT 1697
Score = 47.2 bits (107), Expect = 2e-04
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 4/61 (6%)
Query: 451 CINLPGSFQCRCRDGWRGDGA--TCEDVDECLTNNGGC--HPRATCANTDGSFRCLCDTG 506
C+ + + C C +G++ D A C DV+EC NG C NT+GS+RC C G
Sbjct: 1627 CVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPG 1686
Query: 507 Y 507
Y
Sbjct: 1687 Y 1687
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC----GD 173
++NEC GLC C N G + C C PG D CV ++ G+C G
Sbjct: 501 DINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGP 559
Query: 174 GDC 176
G C
Sbjct: 560 GTC 562
Score = 40.7 bits (91), Expect = 0.013
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
EC G + + C+DI+EC +T G+C + C N G+Y C C G
Sbjct: 486 ECPQGYKRL-NLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPG 530
Score = 40.3 bits (90), Expect = 0.018
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 6/65 (9%)
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGDGAT-CEDVDECLTNNGGCHPRATCANTDGSFRC 501
C PA+ I + Q C G++ T C+D++ECLT G C A C NT GS+ C
Sbjct: 471 CPPRPASPVIE---NGQLECPQGYKRLNLTHCQDINECLTL-GLCKD-AECVNTRGSYLC 525
Query: 502 LCDTG 506
C G
Sbjct: 526 TCRPG 530
Score = 39.9 bits (89), Expect = 0.024
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C +G+ R + C+DI+EC C +C NT GSY CTC GL+
Sbjct: 487 CPQGYK-RLNLTHCQDINECLTLGL-CKDAECVNTRGSYLCTCRPGLM 532
Score = 39.9 bits (89), Expect = 0.024
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Query: 117 MEVNECAAFPG---LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC 158
++VNEC G LC HG C N G + C C PGY ++ C
Sbjct: 1652 VDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1696
Score = 37.9 bits (84), Expect = 0.095
Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 6/50 (12%)
Query: 417 QCPDGYSVKPEQGPACTDDDEC-ELGTCDCHPAADCINLPGSFQCRCRDG 465
+CP GY K C D +EC LG C A+C+N GS+ C CR G
Sbjct: 486 ECPQGY--KRLNLTHCQDINECLTLGLCK---DAECVNTRGSYLCTCRPG 530
Score = 36.7 bits (81), Expect = 0.22
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 1/47 (2%)
Query: 2 TGGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
T CS PL CC G+AW +Q+C CP + ++ Y LC
Sbjct: 1470 TNDVCSEPLRGHRTTYTECCCQDGEAW-SQQCALCPPRSSEVYAQLC 1515
Score = 36.3 bits (80), Expect = 0.29
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 3/67 (4%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE--LGTCDCHPAADCINLPGSFQ 459
C G C + C C +G+ + AC D +EC+ G C N GS++
Sbjct: 1622 CENGRCVRVREGYTCDCFEGFQLDAAH-MACVDVNECDDLNGPAVLCVHGYCENTEGSYR 1680
Query: 460 CRCRDGW 466
C C G+
Sbjct: 1681 CHCSPGY 1687
Score = 35.9 bits (79), Expect = 0.38
Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 6/86 (6%)
Query: 268 QCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRD 327
Q C +GY + + +H CVNT GSY CTCR G L D R
Sbjct: 484 QLECPQGYKRLNL-THCQDINECLTLGLCKDAECVNTRGSYLCTCRPG--LMLDPSRSRC 540
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCT 353
+ + A G C ++G TCT
Sbjct: 541 VSDKAISMLQ---GLCYRSLGPGTCT 563
Score = 35.9 bits (79), Expect = 0.38
Identities = 14/43 (32%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
CS L + +A CCC+ G +WG+ C+ CP + + + +C
Sbjct: 1302 CSSVLGRNTTQAECCCTQ-GASWGD-ACDLCPSEDSAEFSEIC 1342
Score = 35.1 bits (77), Expect = 0.67
Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKK 39
G+C+ PL ++ CC ++G WG C PCP +
Sbjct: 440 GQCANPL-LELTTQEDCCGSVGAFWGVTLCAPCPPR 474
Score = 34.3 bits (75), Expect = 1.2
Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
C DI+EC LC++ C NT G Y C C G
Sbjct: 499 CQDINECLT-LGLCKDAECVNTRGSYLCTCRPG 530
>X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein.
Length = 517
Score = 279 bits (683), Expect = 3e-74
Identities = 129/307 (42%), Positives = 169/307 (55%), Gaps = 23/307 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NEC P LC HG+CRN +G F C C G+ DS+ C D++EC I +CG G C
Sbjct: 232 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 291
Query: 178 NTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT G F C C GY++ K C+DIDEC + LCRGG C NT GS+RCEC G +L+
Sbjct: 292 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS 351
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
P+ +C DI+EC +++ +C NG C N +G YQC C+ GY + +
Sbjct: 352 PNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGG 411
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C+ C N+ GSY C+C+ G+ L D RSC DIDEC C GGQC N G Y C C D
Sbjct: 412 CETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYD 471
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G + A+ TC D++EC DL P +C +G+C NT GSF+C
Sbjct: 472 GFM--ASEDMKTCVDVNEC-DL-------------------NPNICLSGTCENTKGSFIC 509
Query: 417 QCPDGYS 423
C GYS
Sbjct: 510 HCDMGYS 516
Score = 234 bits (572), Expect = 7e-61
Identities = 163/497 (32%), Positives = 217/497 (43%), Gaps = 92/497 (18%)
Query: 129 CGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDV-----------NECEI-VDGVCGDGDC 176
C +G C+N G F C+C D C++ CEI ++G C
Sbjct: 20 CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC 79
Query: 177 HNTEGSF------TCH----CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFR 226
++ G+ C C GY ++ C DIDEC +C+ G CVNT GSF+
Sbjct: 80 CSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQ-CEDIDECEVFPGVCKNGLCVNTRGSFK 138
Query: 227 CECGHGMELAPDRLSCKDI-----------DECSITSG--------ICSNGA------CE 261
C+C GM L C DI +EC++ CS GA CE
Sbjct: 139 CQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECE 198
Query: 262 N----QMGTYQCVCDEG--YAQSTV---KSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCT 311
Y+ +C G +A + K C H C NT GS+ C
Sbjct: 199 ECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCR 258
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQD 371
C G+ L ++ R+C DIDEC CG GQC NT G + C C +G K C D
Sbjct: 259 CDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMK-NCMD 317
Query: 372 IDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPA 431
IDEC Q+ P LC G CHNT GS+ C+CP G+ + P A
Sbjct: 318 IDEC---------------QRD-----PLLCRGGVCHNTEGSYRCECPPGHQLSPNIS-A 356
Query: 432 CTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPR 489
C D +ECEL C P C+NL G +QC C G+ D C D+DEC NGGC
Sbjct: 357 CIDINECELSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCE-- 413
Query: 490 ATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYE 549
C N++GS+ C C G+ + SC DIDEC ++P +C+ G C+N PG Y
Sbjct: 414 TFCTNSEGSYECSCQPGFA-------LMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYR 466
Query: 550 CDCDVGFTRAADGRSCL 566
C C GF + D ++C+
Sbjct: 467 CLCYDGFMASEDMKTCV 483
Score = 229 bits (560), Expect = 2e-59
Identities = 146/430 (33%), Positives = 193/430 (44%), Gaps = 64/430 (14%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVN-----------ECEI 166
+++EC FPG+C +G C N G F C C G D+ C+D+ EC +
Sbjct: 114 DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTL 173
Query: 167 -------VDGVC-------GDGDCH-----NT-EGSFTCHCRPGYKADDFSK---ICVDI 203
+D C G +C NT E C PG+ + + DI
Sbjct: 174 PIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDI 233
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
+EC +LC G+C NT GSF+C C G L + +C DIDEC I+ +C G C N
Sbjct: 234 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 293
Query: 264 MGTYQCVCDEGYAQS-TVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRAD 321
G ++C CDEGY + + C+ C NT GSY C C G L +
Sbjct: 294 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 353
Query: 322 GRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLIST 381
+C DI+EC A C G+C N +G Y C C G + + C DIDEC+
Sbjct: 354 ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY--HSTPDRLFCVDIDECS----- 406
Query: 382 IIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
IM E C N+ GS+ C C G+++ P+Q +CTD DECE
Sbjct: 407 -IMNGGCET---------------FCTNSEGSYECSCQPGFALMPDQR-SCTDIDECEDN 449
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTDGSF 499
C C N+PG ++C C DG+ D TC DV+EC N C TC NT GSF
Sbjct: 450 PNICD-GGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLS-GTCENTKGSF 507
Query: 500 RCLCDTGYKG 509
C CD GY G
Sbjct: 508 ICHCDMGYSG 517
Score = 223 bits (545), Expect = 1e-57
Identities = 148/453 (32%), Positives = 205/453 (45%), Gaps = 76/453 (16%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKIC--VD 202
C GY + K C D++ECE+ GVC +G C NT GSF C C G D +IC +
Sbjct: 100 CGKGYSR-IKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIR 158
Query: 203 IDEC--ADNDALCR---GGR------CVNTA---GSFRCE-------------CGHGMEL 235
++ C D C GR C + G+ CE C G
Sbjct: 159 LETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGF 218
Query: 236 APDRLS-----CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
A ++ KDI+EC + +C++G C N +G+++C CD G+A + + +
Sbjct: 219 ATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDEC 278
Query: 291 XXXXXRC-QHSCVNTPGSYHCTCREGWHLR-ADGRSCRDIDECAGGARPCGGGQCRNTVG 348
C + CVNTPG + C C EG+ ++C DIDEC C GG C NT G
Sbjct: 279 RISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEG 338
Query: 349 SYTCTCTDG--LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
SY C C G L P+ + C DI+EC EL LC G
Sbjct: 339 SYRCECPPGHQLSPNISA----CIDINEC-------------ELSA-------HLCPNGR 374
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N IG + C C GY P++ C D DEC + C C N GS++C C+ G+
Sbjct: 375 CVNLIGKYQCACNPGYHSTPDR-LFCVDIDECSIMNGGCETF--CTNSEGSYECSCQPGF 431
Query: 467 R--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
D +C D+DEC N C C N G +RCLC G+ ++T CV
Sbjct: 432 ALMPDQRSCTDIDECEDNPNICDG-GQCTNIPGEYRCLCYDGFMASE-DMKT------CV 483
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
D++EC +P +C +G C NT G + C CD+G++
Sbjct: 484 DVNECDLNPNICLSGTCENTKGSFICHCDMGYS 516
Score = 169 bits (410), Expect = 3e-41
Identities = 68/160 (42%), Positives = 96/160 (60%), Gaps = 1/160 (0%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++NEC LC +GRC NL+G + C C PGY CVD++EC I++G C + C
Sbjct: 358 IDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGC-ETFC 416
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N+EGS+ C C+PG+ + C DIDEC DN +C GG+C N G +RC C G +
Sbjct: 417 TNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMAS 476
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYA 276
D +C D++EC + IC +G CEN G++ C CD GY+
Sbjct: 477 EDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYS 516
Score = 164 bits (399), Expect = 6e-40
Identities = 75/201 (37%), Positives = 103/201 (51%), Gaps = 2/201 (0%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+++EC P LC G C N G + C+C PG++ C+D+NECE+ +C +G C
Sbjct: 316 MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRC 375
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G + C C PGY + CVDIDEC+ + C C N+ GS+ C C G L
Sbjct: 376 VNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCE-TFCTNSEGSYECSCQPGFALM 434
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXX 295
PD+ SC DIDEC IC G C N G Y+C+C +G+ A +K+
Sbjct: 435 PDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNI 494
Query: 296 RCQHSCVNTPGSYHCTCREGW 316
+C NT GS+ C C G+
Sbjct: 495 CLSGTCENTKGSFICHCDMGY 515
Score = 161 bits (391), Expect = 6e-39
Identities = 124/430 (28%), Positives = 172/430 (40%), Gaps = 71/430 (16%)
Query: 165 EIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVD----------ID-ECADN-DAL 212
+++ C +G C N+ GSF C C D IC++ ID C N +
Sbjct: 14 KMLSSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGA 73
Query: 213 CRGGRCVNTAGS------FRCE----CGHGMELAPDRLSCKDIDECSITSGICSNGACEN 262
+C ++ G+ C+ CG G C+DIDEC + G+C NG C N
Sbjct: 74 TLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKG-TQCEDIDECEVFPGVCKNGLCVN 132
Query: 263 QMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADG 322
G+++C C G R + +C CT R D
Sbjct: 133 TRGSFKCQCPSGM--------TLDATGRICLDIRLE-TCFLRYEDEECTLPIAGRHRMDA 183
Query: 323 RSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG---LVPSAAGAKPTCQDIDECADLI 379
C A G C RNT Y C G KP +DI+EC
Sbjct: 184 CCCS--VGAAWGTEECEECPMRNT-PEYEELCPRGPGFATKEITNGKPFFKDINEC---- 236
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE 439
IP LC G C NTIGSF C+C G+++ E+ CTD DEC
Sbjct: 237 ----------------KMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEE-RNCTDIDECR 279
Query: 440 LGTCDCHPAADCINLPGSFQCRCRDGWRGD---GATCEDVDECLTNNGGCHPRATCANTD 496
+ D C+N PG F+C+C +G+ C D+DEC + C C NT+
Sbjct: 280 ISP-DLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCR-GGVCHNTE 337
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
GS+RC C G++ + +C+DI+EC LC NG C N G Y+C C+ G+
Sbjct: 338 GSYRCECPPGHQLSPN-------ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY 390
Query: 557 TRAADGRSCL 566
D C+
Sbjct: 391 HSTPDRLFCV 400
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
C+ P+ CCCS +G AWG + CE CP + T Y+ LC
Sbjct: 171 CTLPIAGRHRMDACCCS-VGAAWGTEECEECPMRNTPEYEELC 212
>AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant
protein.
Length = 830
Score = 252 bits (617), Expect = 2e-66
Identities = 151/452 (33%), Positives = 217/452 (48%), Gaps = 53/452 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC PG+C +G C N++G F C+C G+ + K C D++EC+ + +C
Sbjct: 200 VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC 259
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS+ C C+PGY+ + C D +EC + +C G+C++T GSF C C G +
Sbjct: 260 INTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTN 318
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
D+ C DI+EC + C NG C N +G++ C C+ G+ S
Sbjct: 319 DDQTMCLDINECERDA--CGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNL 376
Query: 297 CQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
C++ C+NT GS+ C C EG+ + DGR+C DI+EC R C G C+N GSY C C
Sbjct: 377 CRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICP 436
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G S K C+DIDEC V+E PE+C G+C NT GSF
Sbjct: 437 PGY--SLQNEK--CEDIDEC-----------VEE---------PEICALGTCSNTEGSFK 472
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCED 475
C CP+G+S+ G C D + C + P S R+ + + C
Sbjct: 473 CLCPEGFSLS-SSGRRCQD---LRMSYCYAKFEGGKCSSPKS-----RNHSKQE-CCC-- 520
Query: 476 VDECLTNNGGCHPRATC-ANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
L G P C D +FR +C G G G S VD+DEC +P
Sbjct: 521 ---ALKGEGWGDPCELCPTEPDEAFRQICPYG-SGIIVGPDD-----SAVDMDEC-KEPD 570
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C++G C NT G Y C+C G+ A G C+
Sbjct: 571 VCKHGQCINTDGSYRCECPFGYILA--GNECV 600
Score = 241 bits (589), Expect = 6e-63
Identities = 155/461 (33%), Positives = 207/461 (44%), Gaps = 68/461 (14%)
Query: 117 MEVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA+ G LC +G+C N +G F C C GYE TCVD+NEC + C G
Sbjct: 364 IDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGT 423
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N +GS+ C C PGY + + C DIDEC + +C G C NT GSF+C C G L
Sbjct: 424 CQNLDGSYRCICPPGYSLQN--EKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSL 481
Query: 236 APDRLSCKDI--DEC--SITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ C+D+ C G CS+ N +C C +K
Sbjct: 482 SSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNH-SKQECCC-------ALKGEGWGDP--- 530
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWHLRAD-GRSCRDIDECAGGARPCGGGQCRNTVGSY 350
C+ ++ C G + S D+DEC C GQC NT GSY
Sbjct: 531 -----CELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKE-PDVCKHGQCINTDGSY 584
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNT 410
C C G + AG + C D DEC+ + CG G+C N
Sbjct: 585 RCECPFGYI--LAGNE--CVDTDECS---------------------VGNPCGNGTCKNV 619
Query: 411 IGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RG 468
IG F C C +G+ P C D +EC C A C+N GS++C+C G+ R
Sbjct: 620 IGGFECTCEEGFEPGPMM--TCEDINECAQNPLLC--AFRCVNTYGSYECKCPVGYVLRE 675
Query: 469 DGATCEDVDECLTNNGGC-HPRATCANTDGSFRCLCDTGY--KGDGYGLRTVCCVYSCVD 525
D C+D DEC C + C N G++ C+C GY + DG G CVD
Sbjct: 676 DRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEG---------CVD 726
Query: 526 IDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+EC P +CENG C NT G Y C+C+ GFT + + CL
Sbjct: 727 ENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 767
Score = 240 bits (587), Expect = 1e-62
Identities = 176/530 (33%), Positives = 222/530 (41%), Gaps = 81/530 (15%)
Query: 24 LGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPPNQWDRPIDGNMTDIWSQVGGDENGDG 83
LGKAWG CE CP T Y+ LC G PN PI + DI DE +
Sbjct: 1 LGKAWGTP-CEMCPAVNTSEYKILCPG-GEGFRPN----PITVILEDI------DECQEL 48
Query: 84 YGKQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNECAAFPGLCGHGRCRNLL----- 138
G G +VNEC PG+CG G C N +
Sbjct: 49 PGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET-PGICGPGTCYNTVGNYTC 107
Query: 139 ----------GGFTCD------CFPGYEKDS------------KNHTCVDVNECEIVDGV 170
GG C C+ Y D+ K C N +
Sbjct: 108 ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKP 167
Query: 171 CGDGDCHNTEGSFTCHC---RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC 227
C +T+ F C RPG+ D ++ + VDIDEC + +C G C+N GSFRC
Sbjct: 168 CEQCPIPSTD-EFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRC 226
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
EC G L C+DIDEC +C N C N G+Y+C C GY + T
Sbjct: 227 ECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECINTAGSYRCDCKPGY-RFTSTGQCND 284
Query: 287 XXXXXXXXXRCQH-SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN 345
C H C++T GS++C C G+ D C DI+EC A CG G CRN
Sbjct: 285 RNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDA--CGNGTCRN 342
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
T+GS+ C C G + S C D+DECA LC G
Sbjct: 343 TIGSFNCRCNHGFILS---HNNDCIDVDECAS-------------------GNGNLCRNG 380
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C NT+GSF CQC +GY V P+ G C D +EC L C P C NL GS++C C G
Sbjct: 381 QCINTVGSFQCQCNEGYEVAPD-GRTCVDINECLLEPRKCAPGT-CQNLDGSYRCICPPG 438
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
+ CED+DEC+ C TC+NT+GSF+CLC G+ G R
Sbjct: 439 YSLQNEKCEDIDECVEEPEIC-ALGTCSNTEGSFKCLCPEGFSLSSSGRR 487
Score = 168 bits (409), Expect = 4e-41
Identities = 113/349 (32%), Positives = 152/349 (43%), Gaps = 60/349 (17%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDV--NEC--EIVDGVCGD 173
+++EC P +C G C N G F C C G+ S C D+ + C + G C
Sbjct: 448 DIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSS 507
Query: 174 GDCHNT-----------EG-SFTCHCRPGYKADDFSKIC--------------VDIDECA 207
N EG C P + F +IC VD+DEC
Sbjct: 508 PKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK 567
Query: 208 DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTY 267
+ D +C+ G+C+NT GS+RCEC G LA + C D DECS+ + C NG C+N +G +
Sbjct: 568 EPD-VCKHGQCINTDGSYRCECPFGYILAGNE--CVDTDECSVGNP-CGNGTCKNVIGGF 623
Query: 268 QCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRD 327
+C C+EG+ + + C CVNT GSY C C G+ LR D R C+D
Sbjct: 624 ECTCEEGFEPGPMMTCEDINECAQNPLL-CAFRCVNTYGSYECKCPVGYVLREDRRMCKD 682
Query: 328 IDECAGGARPCGGGQ--CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
DEC G C Q C+N +G+Y C C G G C D +EC
Sbjct: 683 EDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEG--CVDENECQTK------- 733
Query: 386 SVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTD 434
P +C G C NT GS+ C+C DG++ P Q C D
Sbjct: 734 -------------PGICENGRCLNTRGSYTCECNDGFTASPNQ-DECLD 768
Score = 151 bits (367), Expect = 5e-36
Identities = 84/233 (36%), Positives = 113/233 (48%), Gaps = 17/233 (7%)
Query: 157 TCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGG 216
+ VD++EC+ D VC G C NT+GS+ C C GY CVD DEC+ + C G
Sbjct: 559 SAVDMDECKEPD-VCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNP-CGNG 614
Query: 217 RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYA 276
C N G F C C G E P ++C+DI+EC+ +C+ C N G+Y+C C GY
Sbjct: 615 TCKNVIGGFECTCEEGFEPGP-MMTCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYV 672
Query: 277 QSTVKSHXXXXXXXXXXXXRC---QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAG 333
+ C Q C N G+Y C C G+ R DG C D +EC
Sbjct: 673 LREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQT 732
Query: 334 GARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
C G+C NT GSYTC C DG S + DEC D+I +++++S
Sbjct: 733 KPGICENGRCLNTRGSYTCECNDGFTAS--------PNQDECLDVILSLLLLS 777
Score = 151 bits (367), Expect = 5e-36
Identities = 79/215 (36%), Positives = 107/215 (49%), Gaps = 9/215 (4%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC P +C HG+C N G + C+C GY + CVD +EC V CG+G C
Sbjct: 561 VDMDECKE-PDVCKHGQCINTDGSYRCECPFGY--ILAGNECVDTDECS-VGNPCGNGTC 616
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G F C C G++ C DI+ECA N LC RCVNT GS+ C+C G L
Sbjct: 617 KNVIGGFECTCEEGFEPGPM-MTCEDINECAQNPLLC-AFRCVNTYGSYECKCPVGYVLR 674
Query: 237 PDRLSCKDIDECSITSGICSNG--ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
DR CKD DEC C+ C+N +GTY C+C GY +
Sbjct: 675 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 734
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDI 328
C++ C+NT GSY C C +G+ + C D+
Sbjct: 735 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDV 769
Score = 64.1 bits (149), Expect = 1e-09
Identities = 40/109 (36%), Positives = 52/109 (47%), Gaps = 11/109 (10%)
Query: 460 CRCRDGWRGDGATC--EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C +G+R + T ED+DEC G C C NT GSF+C C TGY L
Sbjct: 24 CPGGEGFRPNPITVILEDIDECQELPGLCQG-GKCINTFGSFQCRCPTGYY-----LNED 77
Query: 518 CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
V C D++EC P +C G C NT G Y C C + + G +C+
Sbjct: 78 TRV--CDDVNECET-PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCM 123
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 3 GGRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
GG+CS P + + CCC+ G+ WG+ CE CP + +A++ +C
Sbjct: 502 GGKCSSPKSRNHSKQECCCALKGEGWGDP-CELCPTEPDEAFRQIC 546
Score = 45.6 bits (103), Expect = 5e-04
Identities = 19/44 (43%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
Query: 6 CSGPLPTDVLRAVCCCSA-LGKAWGNQRCEPCPKKGTDAYQNLC 48
C G L ++ + +CCCS +G+AW N+ CE CP TD + LC
Sbjct: 141 CDGELLFNMTKKMCCCSYNIGRAW-NKPCEQCPIPSTDEFATLC 183
>BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein.
Length = 743
Score = 237 bits (580), Expect = 8e-62
Identities = 150/436 (34%), Positives = 194/436 (44%), Gaps = 49/436 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
E +EC +CGHG C ++C C PGY ++ CVDVNECE G G C
Sbjct: 61 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 120
Query: 178 NTEGSFTCHCRPGYK--ADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
NT GS+ CHC GY+ + CVD++ECA GG C+N G ++C C G L
Sbjct: 121 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 180
Query: 236 APDRLS-CKDIDECSITSGICSNGACENQMGTYQCV-CDEGYAQSTVKSHXXXXXXXXXX 293
R C+DIDEC S C +G CEN+ G+++C+ C GY
Sbjct: 181 KASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQ--GGGACRDVNECAE 237
Query: 294 XXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C C N PGS+ CTC +G+ DGRSC D+DEC G C G C NT GS+ C
Sbjct: 238 GSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG-DVCDNGICSNTPGSFQC 296
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C G + + C+DIDEC P C G C NT G
Sbjct: 297 QCLSGY--HLSRDRSHCEDIDEC---------------------DFPAACIGGDCINTNG 333
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDG 470
S+ C CP G+ + G C D DEC C P C NL GS+ C C +G+ D
Sbjct: 334 SYRCLCPQGHRL--VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQ 391
Query: 471 ATCEDVD------ECLTN-NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
CE+V+ EC N + + A C C G G+G C +Y C
Sbjct: 392 HGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSL---GAGWG--DHCEIYPC 446
Query: 524 VDIDECANDPTLCENG 539
+ A +LC +G
Sbjct: 447 -PVYSSAEFHSLCPDG 461
Score = 215 bits (526), Expect = 3e-55
Identities = 158/451 (35%), Positives = 202/451 (44%), Gaps = 51/451 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKD--SKNHTCVDVNECEIVDGVCGDG 174
++VNEC A P G G C N G + C C GY + +CVD+NEC +CGDG
Sbjct: 102 VDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDG 160
Query: 175 D-CHNTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRC-ECGH 231
C N G + C+C PGY+ +C DIDEC D + C G+C N GSF+C C
Sbjct: 161 GFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQP 219
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
G + +C+D++EC+ S CS G CEN G+++C C +GYA +
Sbjct: 220 GYR-SQGGGACRDVNECAEGSP-CSPGWCENLPGSFRCTCAQGYAPAP-DGRSCLDVDEC 276
Query: 292 XXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSY 350
C + C NTPGS+ C C G+HL D C DIDEC A C GG C NT GSY
Sbjct: 277 EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPA-ACIGGDCINTNGSY 335
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHN 409
C C G G + CQDIDEC+ Q P LC G+C N
Sbjct: 336 RCLCPQG--HRLVGGR-KCQDIDECS--------------------QDPSLCLPHGACKN 372
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
GS+VC C +G++ P Q D CE H +N + C D
Sbjct: 373 LQGSYVCVCDEGFT--PTQ-----DQHGCEEVEQPHHKKECYLNFDDTVFC---DSVLAT 422
Query: 470 GATCEDVDECLTNNGGCHPRA-TC-ANTDGSFRCLCDTGYKGDGYGLRTV-CCVYSCVDI 526
T ++ L G H C + F LC G KG V + + DI
Sbjct: 423 NVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDG-KGYTQDNNIVNYGIPAHRDI 481
Query: 527 DEC-ANDPTLCENGHCSNTPGGYECDCDVGF 556
DEC +C+ G C NT GYEC C GF
Sbjct: 482 DECMLFGSEICKEGKCVNTQPGYECYCKQGF 512
Score = 214 bits (522), Expect = 8e-55
Identities = 133/373 (35%), Positives = 165/373 (44%), Gaps = 48/373 (12%)
Query: 202 DIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACE 261
+ DEC N +C G CV + C C G P C D++EC G C
Sbjct: 61 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 120
Query: 262 NQMGTYQCVCDEGYAQST-VKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREGWHL 318
N G+Y C C+ GY C C+N PG Y C C G+ L
Sbjct: 121 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 180
Query: 319 RADGRS-CRDIDECAGGARPCGGGQCRNTVGSYTC-TCTDGLVPSAAGAKPTCQDIDECA 376
+A C DIDEC + C G+C N GS+ C C G GA C+D++ECA
Sbjct: 181 KASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQGGGA---CRDVNECA 236
Query: 377 DLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDD 436
+ C G C N GSF C C GY+ P+ G +C D D
Sbjct: 237 E---------------------GSPCSPGWCENLPGSFRCTCAQGYAPAPD-GRSCLDVD 274
Query: 437 ECELG-TCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCA 493
ECE G CD C N PGSFQC+C G+ D + CED+DEC C C
Sbjct: 275 ECEAGDVCD---NGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIG-GDCI 329
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYECDC 552
NT+GS+RCLC G++ G G + C DIDEC+ DP+LC +G C N G Y C C
Sbjct: 330 NTNGSYRCLCPQGHRLVG-GRK-------CQDIDECSQDPSLCLPHGACKNLQGSYVCVC 381
Query: 553 DVGFTRAADGRSC 565
D GFT D C
Sbjct: 382 DEGFTPTQDQHGC 394
Score = 128 bits (309), Expect = 5e-29
Identities = 83/245 (33%), Positives = 110/245 (44%), Gaps = 39/245 (15%)
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
+ DEC CG G+C Y+C C G + C D++EC
Sbjct: 61 ETDECRLNQNICGHGECVPGPPDYSCHCNPGY--RSHPQHRYCVDVNEC----------- 107
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGP-ACTDDDECELGTCDC 445
+P P G G C NT GS+ C C GY + G +C D +EC C
Sbjct: 108 ------EAEPCGP---GRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHL-C 157
Query: 446 HPAADCINLPGSFQCRCRDGWRGDGA---TCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
CIN PG ++C C G+R + CED+DEC + C P C N GSF+C+
Sbjct: 158 GDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDEC-RDPSSC-PDGKCENKPGSFKCI 215
Query: 503 -CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAAD 561
C GY+ G G +C D++ECA + + C G C N PG + C C G+ A D
Sbjct: 216 ACQPGYRSQGGG--------ACRDVNECA-EGSPCSPGWCENLPGSFRCTCAQGYAPAPD 266
Query: 562 GRSCL 566
GRSCL
Sbjct: 267 GRSCL 271
Score = 124 bits (298), Expect = 1e-27
Identities = 139/516 (26%), Positives = 196/516 (37%), Gaps = 114/516 (22%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC A +C +G C N G F C C GY C D++EC+ C GDC
Sbjct: 271 LDVDECEA-GDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDF-PAACIGGDC 328
Query: 177 HNTEGSFTCHCRPGY------KADDFSKICVDIDECADNDALCRGGR----CVNTAGSFR 226
NT GS+ C C G+ K D + D C + A C+ + CV G
Sbjct: 329 INTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGA-CKNLQGSYVCVCDEGFTP 387
Query: 227 CECGHGMELAP-------------DRLSCKDIDECSITSG--ICSNGA-----CE----- 261
+ HG E D + C + ++T CS GA CE
Sbjct: 388 TQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCP 447
Query: 262 -NQMGTYQCVCDEG--YAQST------VKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCT 311
+ +C +G Y Q + +H C+ CVNT Y C
Sbjct: 448 VYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECY 507
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQD 371
C++G++ + C D+DEC + C G C NT G Y C CT S A
Sbjct: 508 CKQGFYYDGNLLECVDVDECLDESN-CRNGVCENTRGGYRCACTPPAEYSPAQR------ 560
Query: 372 IDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPA 431
+C +S +E++++ P+ ++C + + DG P GPA
Sbjct: 561 --QC---------LSPEEMERA--PERRDVCWSQ-----------RGEDGMCAGPLAGPA 596
Query: 432 CT-DDDECELG-----TC-DCHPAADCINLPGSFQCRCRDGW-----------RGDGATC 473
T DD C G C C P + P S Q W R + ++
Sbjct: 597 LTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTS-QSESNSFWDTSPLLLGKPPRDEDSSE 655
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA--- 530
ED DEC +G C PR G C C G++ D R CVDIDEC
Sbjct: 656 EDSDECRCVSGRCVPR------PGGAVCECPGGFQLDASRAR-------CVDIDECRELN 702
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
LC++ C NT G + C C GF R+ +C+
Sbjct: 703 QRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACV 738
Score = 85.4 bits (202), Expect = 5e-16
Identities = 59/163 (36%), Positives = 76/163 (46%), Gaps = 16/163 (9%)
Query: 399 PELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
PEL S T+ F+ P S T+ DEC L C +C+ P +
Sbjct: 27 PELISRPS-PPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHG-ECVPGPPDY 84
Query: 459 QCRCRDGWRG--DGATCEDVDECLTNNGGCHP-RATCANTDGSFRCLCDTGYKGD-GYGL 514
C C G+R C DV+EC C P R C NT GS+ C C+ GY+ G G
Sbjct: 85 SCHCNPGYRSHPQHRYCVDVNECEAEP--CGPGRGICMNTGGSYNCHCNRGYRLHVGAGG 142
Query: 515 RTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYECDCDVGF 556
R SCVD++ECA P LC + G C N PG Y+C+C G+
Sbjct: 143 R------SCVDLNECAK-PHLCGDGGFCINFPGHYKCNCYPGY 178
Score = 42.3 bits (95), Expect = 0.004
Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAY 44
G C+GPL L CC G+ WG Q C PCP +G ++
Sbjct: 586 GMCAGPLAGPALTFDDCCCRQGRGWGAQ-CRPCPPRGAGSH 625
Score = 39.5 bits (88), Expect = 0.031
Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 4/45 (8%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCE--PCPKKGTDAYQNLC 48
C L T+V + CCCS LG WG+ CE PCP + + +LC
Sbjct: 416 CDSVLATNVTQQECCCS-LGAGWGD-HCEIYPCPVYSSAEFHSLC 458
>AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.
Length = 1382
Score = 237 bits (580), Expect = 8e-62
Identities = 150/436 (34%), Positives = 194/436 (44%), Gaps = 49/436 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
E +EC +CGHG C ++C C PGY ++ CVDVNECE G G C
Sbjct: 653 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 712
Query: 178 NTEGSFTCHCRPGYK--ADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
NT GS+ CHC GY+ + CVD++ECA GG C+N G ++C C G L
Sbjct: 713 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 772
Query: 236 APDRLS-CKDIDECSITSGICSNGACENQMGTYQCV-CDEGYAQSTVKSHXXXXXXXXXX 293
R C+DIDEC S C +G CEN+ G+++C+ C GY
Sbjct: 773 KASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQ--GGGACRDVNECAE 829
Query: 294 XXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C C N PGS+ CTC +G+ DGRSC D+DEC G C G C NT GS+ C
Sbjct: 830 GSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG-DVCDNGICSNTPGSFQC 888
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C G + + C+DIDEC P C G C NT G
Sbjct: 889 QCLSGY--HLSRDRSHCEDIDEC---------------------DFPAACIGGDCINTNG 925
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDG 470
S+ C CP G+ + G C D DEC C P C NL GS+ C C +G+ D
Sbjct: 926 SYRCLCPQGHRL--VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQ 983
Query: 471 ATCEDVD------ECLTN-NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
CE+V+ EC N + + A C C G G+G C +Y C
Sbjct: 984 HGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSL---GAGWG--DHCEIYPC 1038
Query: 524 VDIDECANDPTLCENG 539
+ A +LC +G
Sbjct: 1039 -PVYSSAEFHSLCPDG 1053
Score = 215 bits (526), Expect = 3e-55
Identities = 158/451 (35%), Positives = 202/451 (44%), Gaps = 51/451 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKD--SKNHTCVDVNECEIVDGVCGDG 174
++VNEC A P G G C N G + C C GY + +CVD+NEC +CGDG
Sbjct: 694 VDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDG 752
Query: 175 D-CHNTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRC-ECGH 231
C N G + C+C PGY+ +C DIDEC D + C G+C N GSF+C C
Sbjct: 753 GFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQP 811
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
G + +C+D++EC+ S CS G CEN G+++C C +GYA +
Sbjct: 812 GYR-SQGGGACRDVNECAEGSP-CSPGWCENLPGSFRCTCAQGYAPAP-DGRSCLDVDEC 868
Query: 292 XXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSY 350
C + C NTPGS+ C C G+HL D C DIDEC A C GG C NT GSY
Sbjct: 869 EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPA-ACIGGDCINTNGSY 927
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHN 409
C C G G + CQDIDEC+ Q P LC G+C N
Sbjct: 928 RCLCPQG--HRLVGGR-KCQDIDECS--------------------QDPSLCLPHGACKN 964
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
GS+VC C +G++ P Q D CE H +N + C D
Sbjct: 965 LQGSYVCVCDEGFT--PTQ-----DQHGCEEVEQPHHKKECYLNFDDTVFC---DSVLAT 1014
Query: 470 GATCEDVDECLTNNGGCHPRA-TC-ANTDGSFRCLCDTGYKGDGYGLRTV-CCVYSCVDI 526
T ++ L G H C + F LC G KG V + + DI
Sbjct: 1015 NVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDG-KGYTQDNNIVNYGIPAHRDI 1073
Query: 527 DEC-ANDPTLCENGHCSNTPGGYECDCDVGF 556
DEC +C+ G C NT GYEC C GF
Sbjct: 1074 DECMLFGSEICKEGKCVNTQPGYECYCKQGF 1104
Score = 214 bits (522), Expect = 8e-55
Identities = 133/373 (35%), Positives = 165/373 (44%), Gaps = 48/373 (12%)
Query: 202 DIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACE 261
+ DEC N +C G CV + C C G P C D++EC G C
Sbjct: 653 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 712
Query: 262 NQMGTYQCVCDEGYAQST-VKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREGWHL 318
N G+Y C C+ GY C C+N PG Y C C G+ L
Sbjct: 713 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 772
Query: 319 RADGRS-CRDIDECAGGARPCGGGQCRNTVGSYTC-TCTDGLVPSAAGAKPTCQDIDECA 376
+A C DIDEC + C G+C N GS+ C C G GA C+D++ECA
Sbjct: 773 KASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQGGGA---CRDVNECA 828
Query: 377 DLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDD 436
+ C G C N GSF C C GY+ P+ G +C D D
Sbjct: 829 E---------------------GSPCSPGWCENLPGSFRCTCAQGYAPAPD-GRSCLDVD 866
Query: 437 ECELG-TCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCA 493
ECE G CD C N PGSFQC+C G+ D + CED+DEC C C
Sbjct: 867 ECEAGDVCD---NGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIG-GDCI 921
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYECDC 552
NT+GS+RCLC G++ G G + C DIDEC+ DP+LC +G C N G Y C C
Sbjct: 922 NTNGSYRCLCPQGHRLVG-GRK-------CQDIDECSQDPSLCLPHGACKNLQGSYVCVC 973
Query: 553 DVGFTRAADGRSC 565
D GFT D C
Sbjct: 974 DEGFTPTQDQHGC 986
Score = 128 bits (309), Expect = 5e-29
Identities = 83/245 (33%), Positives = 110/245 (44%), Gaps = 39/245 (15%)
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
+ DEC CG G+C Y+C C G + C D++EC
Sbjct: 653 ETDECRLNQNICGHGECVPGPPDYSCHCNPGY--RSHPQHRYCVDVNEC----------- 699
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGP-ACTDDDECELGTCDC 445
+P P G G C NT GS+ C C GY + G +C D +EC C
Sbjct: 700 ------EAEPCGP---GRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHL-C 749
Query: 446 HPAADCINLPGSFQCRCRDGWRGDGA---TCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
CIN PG ++C C G+R + CED+DEC + C P C N GSF+C+
Sbjct: 750 GDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDEC-RDPSSC-PDGKCENKPGSFKCI 807
Query: 503 -CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAAD 561
C GY+ G G +C D++ECA + + C G C N PG + C C G+ A D
Sbjct: 808 ACQPGYRSQGGG--------ACRDVNECA-EGSPCSPGWCENLPGSFRCTCAQGYAPAPD 858
Query: 562 GRSCL 566
GRSCL
Sbjct: 859 GRSCL 863
Score = 124 bits (299), Expect = 8e-28
Identities = 146/541 (26%), Positives = 198/541 (36%), Gaps = 117/541 (21%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC A +C +G C N G F C C GY C D++EC+ C GDC
Sbjct: 863 LDVDECEA-GDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDF-PAACIGGDC 920
Query: 177 HNTEGSFTCHCRPGY------KADDFSKICVDIDECADNDALCRGGR----CVNTAGSFR 226
NT GS+ C C G+ K D + D C + A C+ + CV G
Sbjct: 921 INTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGA-CKNLQGSYVCVCDEGFTP 979
Query: 227 CECGHGMELAP-------------DRLSCKDIDECSITSG--ICSNGA-----CE----- 261
+ HG E D + C + ++T CS GA CE
Sbjct: 980 TQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCP 1039
Query: 262 -NQMGTYQCVCDEG--YAQST------VKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCT 311
+ +C +G Y Q + +H C+ CVNT Y C
Sbjct: 1040 VYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECY 1099
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQD 371
C++G++ + C D+DEC + C G C NT G Y C CT S A + C
Sbjct: 1100 CKQGFYYDGNLLECVDVDECLDESN-CRNGVCENTRGGYRCACTPPAEYSPAQRQ--CLS 1156
Query: 372 IDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC-------PDGYSV 424
+E M VDE Q P C G C N GS+ C+C P G
Sbjct: 1157 PEE----------MDVDECQD------PAACRPGRCVNLPGSYRCECRPPWVPGPSGRDC 1200
Query: 425 KPEQGP---ACTDDDEC-----ELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
+ + P A D C E G C A + C CR G RG GA C
Sbjct: 1201 QLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFD---DCCCRQG-RGWGAQCRPC 1256
Query: 477 ------DECLTNNG-------------GCHPRATCANTDGSFRCLCDTGY---KGDGY-- 512
C T+ G PR ++ + S C C +G + G
Sbjct: 1257 PPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVC 1316
Query: 513 ----GLRTVCCVYSCVDIDECA---NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G + CVDIDEC LC++ C NT G + C C GF R+ +C
Sbjct: 1317 ECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1376
Query: 566 L 566
+
Sbjct: 1377 V 1377
Score = 101 bits (243), Expect = 5e-21
Identities = 99/371 (26%), Positives = 146/371 (39%), Gaps = 51/371 (13%)
Query: 223 GSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS 282
G +C G + + C+DI+EC++ G+C +G C N G+Y+CVC G++ ++
Sbjct: 414 GEVGADCPQGYKRL-NSTHCQDINECAMP-GVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 471
Query: 283 HXXXXXXXXXXX--------XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG 334
+CQH C C G A + C D A
Sbjct: 472 QCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRC-PTDGTAAF 530
Query: 335 ARPCGGGQCRNTVGSYTCTCTDG-----------------LVPSAAGAKPTCQDIDECAD 377
C G+ + + S+ G +P + P +D +E
Sbjct: 531 KEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERG 590
Query: 378 LISTIIMMSVDELQKS-----VDPQ--IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGP 430
+ + + +Q+S P PEL S T+ F+ P S
Sbjct: 591 VTTDSPVSEERSVQQSHPTATTTPARPYPELISRPS-PPTMRWFLPDLPPSRSAVEIAPT 649
Query: 431 ACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHP 488
T+ DEC L C +C+ P + C C G+R C DV+EC C P
Sbjct: 650 QVTETDECRLNQNICGHG-ECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP--CGP 706
Query: 489 -RATCANTDGSFRCLCDTGYKGD-GYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTP 545
R C NT GS+ C C+ GY+ G G R SCVD++ECA P LC + G C N P
Sbjct: 707 GRGICMNTGGSYNCHCNRGYRLHVGAGGR------SCVDLNECAK-PHLCGDGGFCINFP 759
Query: 546 GGYECDCDVGF 556
G Y+C+C G+
Sbjct: 760 GHYKCNCYPGY 770
Score = 54.8 bits (126), Expect = 8e-07
Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSK 198
G DC GY++ + H C D+NEC + GVC GDC N GS+ C C PG+
Sbjct: 414 GEVGADCPQGYKRLNSTH-CQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 471
Query: 199 ICV 201
C+
Sbjct: 472 QCI 474
Score = 54.0 bits (124), Expect = 1e-06
Identities = 23/46 (50%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 5 RCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIA 50
+C PL T + R +CCCS +GKAWG RC+ CP GT A++ +C A
Sbjct: 493 QCQHPLTTRLTRQLCCCS-VGKAWG-ARCQRCPTDGTAAFKEICPA 536
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/62 (43%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
G C GYK + S C DI+ECA +CR G C+N GS+RC C G L P R
Sbjct: 414 GEVGADCPQGYKRLN-STHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 471
Query: 241 SC 242
C
Sbjct: 472 QC 473
Score = 44.4 bits (100), Expect = 0.001
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DI+ECA P +C +G C N PG Y C C G + C+
Sbjct: 432 CQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI 474
Score = 43.2 bits (97), Expect = 0.003
Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV 159
++NECA PG+C HG C N G + C C PG+ C+
Sbjct: 434 DINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI 474
Score = 42.3 bits (95), Expect = 0.004
Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAY 44
G C+GPL L CC G+ WG Q C PCP +G ++
Sbjct: 1225 GMCAGPLAGPALTFDDCCCRQGRGWGAQ-CRPCPPRGAGSH 1264
Score = 39.5 bits (88), Expect = 0.031
Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 4/45 (8%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCE--PCPKKGTDAYQNLC 48
C L T+V + CCCS LG WG+ CE PCP + + +LC
Sbjct: 1008 CDSVLATNVTQQECCCS-LGAGWGD-HCEIYPCPVYSSAEFHSLC 1050
Score = 36.3 bits (80), Expect = 0.29
Identities = 13/32 (40%), Positives = 19/32 (59%), Gaps = 1/32 (3%)
Query: 7 SGPLPTDVLRAVCCCSALGKAWGNQRCEPCPK 38
S PLP + + CC ++G AWG +C CP+
Sbjct: 370 SNPLP-GLTKQEDCCGSIGTAWGQSKCHKCPQ 400
>AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming growth
factor beta binding protein 3 protein.
Length = 1256
Score = 237 bits (580), Expect = 8e-62
Identities = 150/436 (34%), Positives = 194/436 (44%), Gaps = 49/436 (11%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
E +EC +CGHG C ++C C PGY ++ CVDVNECE G G C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 178 NTEGSFTCHCRPGYK--ADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
NT GS+ CHC GY+ + CVD++ECA GG C+N G ++C C G L
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 693
Query: 236 APDRLS-CKDIDECSITSGICSNGACENQMGTYQCV-CDEGYAQSTVKSHXXXXXXXXXX 293
R C+DIDEC S C +G CEN+ G+++C+ C GY
Sbjct: 694 KASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQ--GGGACRDVNECAE 750
Query: 294 XXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C C N PGS+ CTC +G+ DGRSC D+DEC G C G C NT GS+ C
Sbjct: 751 GSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG-DVCDNGICSNTPGSFQC 809
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C G + + C+DIDEC P C G C NT G
Sbjct: 810 QCLSGY--HLSRDRSHCEDIDEC---------------------DFPAACIGGDCINTNG 846
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDG 470
S+ C CP G+ + G C D DEC C P C NL GS+ C C +G+ D
Sbjct: 847 SYRCLCPQGHRL--VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQ 904
Query: 471 ATCEDVD------ECLTN-NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
CE+V+ EC N + + A C C G G+G C +Y C
Sbjct: 905 HGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSL---GAGWG--DHCEIYPC 959
Query: 524 VDIDECANDPTLCENG 539
+ A +LC +G
Sbjct: 960 -PVYSSAEFHSLCPDG 974
Score = 215 bits (526), Expect = 3e-55
Identities = 158/451 (35%), Positives = 202/451 (44%), Gaps = 51/451 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKD--SKNHTCVDVNECEIVDGVCGDG 174
++VNEC A P G G C N G + C C GY + +CVD+NEC +CGDG
Sbjct: 615 VDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDG 673
Query: 175 D-CHNTEGSFTCHCRPGYKAD-DFSKICVDIDECADNDALCRGGRCVNTAGSFRC-ECGH 231
C N G + C+C PGY+ +C DIDEC D + C G+C N GSF+C C
Sbjct: 674 GFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQP 732
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
G + +C+D++EC+ S CS G CEN G+++C C +GYA +
Sbjct: 733 GYR-SQGGGACRDVNECAEGSP-CSPGWCENLPGSFRCTCAQGYAPAP-DGRSCLDVDEC 789
Query: 292 XXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSY 350
C + C NTPGS+ C C G+HL D C DIDEC A C GG C NT GSY
Sbjct: 790 EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPA-ACIGGDCINTNGSY 848
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHN 409
C C G G + CQDIDEC+ Q P LC G+C N
Sbjct: 849 RCLCPQG--HRLVGGR-KCQDIDECS--------------------QDPSLCLPHGACKN 885
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
GS+VC C +G++ P Q D CE H +N + C D
Sbjct: 886 LQGSYVCVCDEGFT--PTQ-----DQHGCEEVEQPHHKKECYLNFDDTVFC---DSVLAT 935
Query: 470 GATCEDVDECLTNNGGCHPRA-TC-ANTDGSFRCLCDTGYKGDGYGLRTV-CCVYSCVDI 526
T ++ L G H C + F LC G KG V + + DI
Sbjct: 936 NVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDG-KGYTQDNNIVNYGIPAHRDI 994
Query: 527 DEC-ANDPTLCENGHCSNTPGGYECDCDVGF 556
DEC +C+ G C NT GYEC C GF
Sbjct: 995 DECMLFGSEICKEGKCVNTQPGYECYCKQGF 1025
Score = 214 bits (522), Expect = 8e-55
Identities = 133/373 (35%), Positives = 165/373 (44%), Gaps = 48/373 (12%)
Query: 202 DIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACE 261
+ DEC N +C G CV + C C G P C D++EC G C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 262 NQMGTYQCVCDEGYAQST-VKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREGWHL 318
N G+Y C C+ GY C C+N PG Y C C G+ L
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 693
Query: 319 RADGRS-CRDIDECAGGARPCGGGQCRNTVGSYTC-TCTDGLVPSAAGAKPTCQDIDECA 376
+A C DIDEC + C G+C N GS+ C C G GA C+D++ECA
Sbjct: 694 KASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQGGGA---CRDVNECA 749
Query: 377 DLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDD 436
+ C G C N GSF C C GY+ P+ G +C D D
Sbjct: 750 E---------------------GSPCSPGWCENLPGSFRCTCAQGYAPAPD-GRSCLDVD 787
Query: 437 ECELG-TCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCA 493
ECE G CD C N PGSFQC+C G+ D + CED+DEC C C
Sbjct: 788 ECEAGDVCD---NGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIG-GDCI 842
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYECDC 552
NT+GS+RCLC G++ G G + C DIDEC+ DP+LC +G C N G Y C C
Sbjct: 843 NTNGSYRCLCPQGHRLVG-GRK-------CQDIDECSQDPSLCLPHGACKNLQGSYVCVC 894
Query: 553 DVGFTRAADGRSC 565
D GFT D C
Sbjct: 895 DEGFTPTQDQHGC 907
Score = 128 bits (309), Expect = 5e-29
Identities = 83/245 (33%), Positives = 110/245 (44%), Gaps = 39/245 (15%)
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
+ DEC CG G+C Y+C C G + C D++EC
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGY--RSHPQHRYCVDVNEC----------- 620
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGP-ACTDDDECELGTCDC 445
+P P G G C NT GS+ C C GY + G +C D +EC C
Sbjct: 621 ------EAEPCGP---GRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHL-C 670
Query: 446 HPAADCINLPGSFQCRCRDGWRGDGA---TCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
CIN PG ++C C G+R + CED+DEC + C P C N GSF+C+
Sbjct: 671 GDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDEC-RDPSSC-PDGKCENKPGSFKCI 728
Query: 503 -CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAAD 561
C GY+ G G +C D++ECA + + C G C N PG + C C G+ A D
Sbjct: 729 ACQPGYRSQGGG--------ACRDVNECA-EGSPCSPGWCENLPGSFRCTCAQGYAPAPD 779
Query: 562 GRSCL 566
GRSCL
Sbjct: 780 GRSCL 784
Score = 124 bits (298), Expect = 1e-27
Identities = 139/516 (26%), Positives = 196/516 (37%), Gaps = 114/516 (22%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++V+EC A +C +G C N G F C C GY C D++EC+ C GDC
Sbjct: 784 LDVDECEA-GDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDF-PAACIGGDC 841
Query: 177 HNTEGSFTCHCRPGY------KADDFSKICVDIDECADNDALCRGGR----CVNTAGSFR 226
NT GS+ C C G+ K D + D C + A C+ + CV G
Sbjct: 842 INTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGA-CKNLQGSYVCVCDEGFTP 900
Query: 227 CECGHGMELAP-------------DRLSCKDIDECSITSG--ICSNGA-----CE----- 261
+ HG E D + C + ++T CS GA CE
Sbjct: 901 TQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCP 960
Query: 262 -NQMGTYQCVCDEG--YAQST------VKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCT 311
+ +C +G Y Q + +H C+ CVNT Y C
Sbjct: 961 VYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECY 1020
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQD 371
C++G++ + C D+DEC + C G C NT G Y C CT S A
Sbjct: 1021 CKQGFYYDGNLLECVDVDECLDESN-CRNGVCENTRGGYRCACTPPAEYSPAQR------ 1073
Query: 372 IDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPA 431
+C +S +E++++ P+ ++C + + DG P GPA
Sbjct: 1074 --QC---------LSPEEMERA--PERRDVCWSQ-----------RGEDGMCAGPLAGPA 1109
Query: 432 CT-DDDECELG-----TC-DCHPAADCINLPGSFQCRCRDGW-----------RGDGATC 473
T DD C G C C P + P S Q W R + ++
Sbjct: 1110 LTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTS-QSESNSFWDTSPLLLGKPPRDEDSSE 1168
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA--- 530
ED DEC +G C PR G C C G++ D R CVDIDEC
Sbjct: 1169 EDSDECRCVSGRCVPR------PGGAVCECPGGFQLDASRAR-------CVDIDECRELN 1215
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
LC++ C NT G + C C GF R+ +C+
Sbjct: 1216 QRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACV 1251
Score = 101 bits (243), Expect = 5e-21
Identities = 99/371 (26%), Positives = 146/371 (39%), Gaps = 51/371 (13%)
Query: 223 GSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS 282
G +C G + + C+DI+EC++ G+C +G C N G+Y+CVC G++ ++
Sbjct: 335 GEVGADCPQGYKRL-NSTHCQDINECAMP-GVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 283 HXXXXXXXXXXX--------XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG 334
+CQH C C G A + C D A
Sbjct: 393 QCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRC-PTDGTAAF 451
Query: 335 ARPCGGGQCRNTVGSYTCTCTDG-----------------LVPSAAGAKPTCQDIDECAD 377
C G+ + + S+ G +P + P +D +E
Sbjct: 452 KEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERG 511
Query: 378 LISTIIMMSVDELQKS-----VDPQ--IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGP 430
+ + + +Q+S P PEL S T+ F+ P S
Sbjct: 512 VTTDSPVSEERSVQQSHPTATTTPARPYPELISRPS-PPTMRWFLPDLPPSRSAVEIAPT 570
Query: 431 ACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHP 488
T+ DEC L C +C+ P + C C G+R C DV+EC C P
Sbjct: 571 QVTETDECRLNQNICGHG-ECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP--CGP 627
Query: 489 -RATCANTDGSFRCLCDTGYKGD-GYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTP 545
R C NT GS+ C C+ GY+ G G R SCVD++ECA P LC + G C N P
Sbjct: 628 GRGICMNTGGSYNCHCNRGYRLHVGAGGR------SCVDLNECAK-PHLCGDGGFCINFP 680
Query: 546 GGYECDCDVGF 556
G Y+C+C G+
Sbjct: 681 GHYKCNCYPGY 691
Score = 54.8 bits (126), Expect = 8e-07
Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSK 198
G DC GY++ + H C D+NEC + GVC GDC N GS+ C C PG+
Sbjct: 335 GEVGADCPQGYKRLNSTH-CQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 199 ICV 201
C+
Sbjct: 393 QCI 395
Score = 54.0 bits (124), Expect = 1e-06
Identities = 23/46 (50%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 5 RCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIA 50
+C PL T + R +CCCS +GKAWG RC+ CP GT A++ +C A
Sbjct: 414 QCQHPLTTRLTRQLCCCS-VGKAWG-ARCQRCPTDGTAAFKEICPA 457
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/62 (43%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
G C GYK + S C DI+ECA +CR G C+N GS+RC C G L P R
Sbjct: 335 GEVGADCPQGYKRLN-STHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 241 SC 242
C
Sbjct: 393 QC 394
Score = 44.4 bits (100), Expect = 0.001
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C DI+ECA P +C +G C N PG Y C C G + C+
Sbjct: 353 CQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI 395
Score = 43.2 bits (97), Expect = 0.003
Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV 159
++NECA PG+C HG C N G + C C PG+ C+
Sbjct: 355 DINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI 395
Score = 42.3 bits (95), Expect = 0.004
Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAY 44
G C+GPL L CC G+ WG Q C PCP +G ++
Sbjct: 1099 GMCAGPLAGPALTFDDCCCRQGRGWGAQ-CRPCPPRGAGSH 1138
Score = 39.5 bits (88), Expect = 0.031
Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 4/45 (8%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCE--PCPKKGTDAYQNLC 48
C L T+V + CCCS LG WG+ CE PCP + + +LC
Sbjct: 929 CDSVLATNVTQQECCCS-LGAGWGD-HCEIYPCPVYSSAEFHSLC 971
Score = 36.3 bits (80), Expect = 0.29
Identities = 13/32 (40%), Positives = 19/32 (59%), Gaps = 1/32 (3%)
Query: 7 SGPLPTDVLRAVCCCSALGKAWGNQRCEPCPK 38
S PLP + + CC ++G AWG +C CP+
Sbjct: 291 SNPLP-GLTKQEDCCGSIGTAWGQSKCHKCPQ 321
>AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens
cDNA FLJ16233 fis, clone FEBRA2028256, moderately
similar to FIBRILLIN 2 PRECURSOR. ).
Length = 872
Score = 236 bits (577), Expect = 2e-61
Identities = 153/461 (33%), Positives = 199/461 (43%), Gaps = 32/461 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNECA PG+C +G C N G F C+C GY D CVD +EC V CG G C
Sbjct: 190 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCT 248
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G F C C G++ C DIDEC+ N LC RC NT GS+ C C G L
Sbjct: 249 NVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLC-AFRCHNTEGSYLCTCPAGYTLRE 306
Query: 238 DRLSCKDIDECSITSGIC-SNG-ACENQMGTYQCVCDEGYAQSTVKSHX-XXXXXXXXXX 294
D C+D+DEC+ C + G C+N +GT+ CVC G
Sbjct: 307 DGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQP 366
Query: 295 XRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN-TVGSYTC 352
C + CVNT GS+ C C EG+ C DI + A CR+ + S
Sbjct: 367 DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVL-QTMCRSLSSSSEAV 425
Query: 353 TCTDGLVPSAAGAKPTCQ-----DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
T + G P C+ L + + + LC G C
Sbjct: 426 TRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGEC 485
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW- 466
N++GSF C C GY+ C D DEC C C N GSF C C G+
Sbjct: 486 INSLGSFRCHCQAGYT-PDATATTCLDMDECSQVPKPC--TFLCKNTKGSFLCSCPRGYL 542
Query: 467 -RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
DG TC+D+DEC + C + C NT G+F C C G+ +C D
Sbjct: 543 LEEDGRTCKDLDECTSRQHNC--QFLCVNTVGAFTCRCPPGFTQHH---------QACFD 591
Query: 526 IDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
++EC + P C++G C N GGY C C GFT+ + C+
Sbjct: 592 VNEC-DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCV 630
Score = 222 bits (543), Expect = 2e-57
Identities = 148/447 (33%), Positives = 199/447 (44%), Gaps = 64/447 (14%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG-D 175
+++EC+ P LC RC N G + C C GY C DV+EC C G +
Sbjct: 272 DIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGME 330
Query: 176 CHNTEGSFTCHCRPGYKADDFS-KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C N G+F C C PG + S + C D +EC LC GRCVNTAGSFRC+C G +
Sbjct: 331 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 390
Query: 235 LAPDRLSCKDIDE----CSITSGICSNGACENQMGTY-QCVCDEGYAQSTVKSHXXXXXX 289
+P C DI + + +C + + ++ T +C C G
Sbjct: 391 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGP---------- 440
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
RC+ + +Y C G A+GR D+DEC A C G+C N++GS
Sbjct: 441 ------RCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLCAHGECINSLGS 491
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
+ C C G P A TC D+DEC+ Q+P+ C C N
Sbjct: 492 FRCHCQAGYTPDATAT--TCLDMDECS--------------------QVPKPC-TFLCKN 528
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
T GSF+C CP GY ++ E G C D DEC +C C+N G+F CRC G+
Sbjct: 529 TKGSFLCSCPRGYLLE-EDGRTCKDLDECTSRQHNCQFL--CVNTVGAFTCRCPPGFTQH 585
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
C DV+EC +G + C N G +RC C G+ + CVD +EC
Sbjct: 586 HQACFDVNEC---DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQ-------CVDENEC 635
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGF 556
A P C + C NT GG+ C C GF
Sbjct: 636 ALSPPTCGSASCRNTLGGFRCVCPSGF 662
Score = 178 bits (433), Expect = 5e-44
Identities = 90/248 (36%), Positives = 120/248 (48%), Gaps = 8/248 (3%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC LC HG C N LG F C C GY D+ TC+D++EC V C C
Sbjct: 469 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCK 527
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT+GSF C C GY ++ + C D+DEC C+ CVNT G+F C C G
Sbjct: 528 NTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ-FLCVNTVGAFTCRCPPG--FTQ 584
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
+C D++EC C +G C+NQ+G Y+C C +G+ Q + + C
Sbjct: 585 HHQACFDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTC 642
Query: 298 -QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
SC NT G + C C G+ C+D+DECAG PC C NT G + C C
Sbjct: 643 GSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPC-SYSCANTPGGFLCGCPQ 701
Query: 357 GLVPSAAG 364
G + G
Sbjct: 702 GYFRAGQG 709
Score = 173 bits (422), Expect = 1e-42
Identities = 95/264 (35%), Positives = 122/264 (46%), Gaps = 30/264 (11%)
Query: 160 DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCV 219
DV+EC ++ +C G+C N+ GSF CHC+ GY D + C+D+DEC+ C C
Sbjct: 469 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTF-LCK 527
Query: 220 NTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQST 279
NT GSF C C G L D +CKD+DEC+ C C N +G + C C G+ Q
Sbjct: 528 NTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFTQH- 585
Query: 280 VKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
RCQH C N G Y C+C +G+ + C D +ECA CG
Sbjct: 586 --HQACFDVNECDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 643
Query: 340 GGQCRNTVGSYTCTCTDGL-VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQI 398
CRNT+G + C C G A G CQD+DECA
Sbjct: 644 SASCRNTLGGFRCVCPSGFDFDQALGG---CQDVDECAGRRGP----------------- 683
Query: 399 PELCGAGSCHNTIGSFVCQCPDGY 422
C + SC NT G F+C CP GY
Sbjct: 684 ---C-SYSCANTPGGFLCGCPQGY 703
Score = 155 bits (376), Expect = 4e-37
Identities = 106/348 (30%), Positives = 150/348 (43%), Gaps = 46/348 (13%)
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
S +D++EC+ G+C+NG C N G+++C C GY+ + Q +
Sbjct: 187 SREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 246
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP 360
C N G + C C +G+ +C DIDEC+ C +C NT GSY CTC G
Sbjct: 247 CTNVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLC-AFRCHNTEGSYLCTCPAGYTL 304
Query: 361 SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD 420
GA C+D+DECAD Q+ + E C N IG+F C CP
Sbjct: 305 REDGA--MCRDVDECAD------------GQQDCHARGME------CKNLIGTFACVCPP 344
Query: 421 GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG--ATCEDVDE 478
G P G CTDD+EC D C+N GSF+C C +G++ C D+ +
Sbjct: 345 GMRPLPGSGEGCTDDNECH-AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 403
Query: 479 --CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC------VYSCV------ 524
C R+ ++++ R C G G G+G R C Y +
Sbjct: 404 GPCFAEVLQTMCRSLSSSSEAVTRAECCCG-GGRGWGPRCELCPLPGTSAYRKLCPHGSG 462
Query: 525 ------DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
D+DEC LC +G C N+ G + C C G+T A +CL
Sbjct: 463 YTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCL 510
Score = 75.8 bits (178), Expect = 4e-13
Identities = 43/98 (43%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Query: 460 CRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C R G + EDV+EC N G C C NTDGSFRC C GY D G+
Sbjct: 175 CVSRRAVPGPDDSREDVNECAENPGVC-TNGVCVNTDGSFRCECPFGYSLDFTGI----- 228
Query: 520 VYSCVDIDECA-NDPTLCENGHCSNTPGGYECDCDVGF 556
+CVD DEC+ P C G C+N GG+EC C GF
Sbjct: 229 --NCVDTDECSVGHP--CGQGTCTNVIGGFECACADGF 262
Score = 72.5 bits (170), Expect = 4e-12
Identities = 34/75 (45%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++ NECA P CG CRN LGGF C C G++ D C DV+EC G C C
Sbjct: 630 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPC-SYSC 688
Query: 177 HNTEGSFTCHCRPGY 191
NT G F C C GY
Sbjct: 689 ANTPGGFLCGCPQGY 703
Score = 46.0 bits (104), Expect = 4e-04
Identities = 20/35 (57%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 14 VLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLC 48
V RA CCC G+ WG RCE CP GT AY+ LC
Sbjct: 425 VTRAECCCGG-GRGWG-PRCELCPLPGTSAYRKLC 457
Score = 37.5 bits (83), Expect = 0.13
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV 159
+V+ECA G C + C N GGF C C GY + + H CV
Sbjct: 673 DVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQGH-CV 712
>X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein.
Length = 1184
Score = 231 bits (565), Expect = 5e-60
Identities = 154/425 (36%), Positives = 197/425 (46%), Gaps = 59/425 (13%)
Query: 134 CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----CR 188
C + G C CFPGY + +C D+NEC C G+ C NT GSF C+ C
Sbjct: 693 CSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCE 752
Query: 189 PGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRCE----CGHGMELAPDRLSCK 243
PGY D C D+DECA C+ G C NT GSF C+ C G P+ +C
Sbjct: 753 PGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCV 809
Query: 244 DIDECSITSGICSNG-ACENQMGTYQC-----VCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
DI+EC+ S C G +C N +G+Y C +C GY S + RC
Sbjct: 810 DINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRC 869
Query: 298 QHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDEC-AGGARPCGGGQCRNTVGSYTCTC 354
C N PGSY C C+ G+ A GR C D++EC A R C C NT+GSY C+C
Sbjct: 870 GEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSC 928
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + +A G + C+D++EC E Q+ C C N GS+
Sbjct: 929 ASGFLLAADGKR--CEDVNEC-------------EAQR---------CSQ-ECANIYGSY 963
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD-GWR--GDGA 471
C C GY + E G CTD DEC G C+N+PGS+QC C + G+ +G
Sbjct: 964 QCYCRQGYQLA-EDGHTCTDIDECAQGA-GILCTFRCLNVPGSYQCACPEQGYTMTANGR 1021
Query: 472 TCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLRTVCCVYSCVDIDE 528
+C+DVDEC C TC N GSFRCL C Y +T C +C D E
Sbjct: 1022 SCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVS---KTKCERTTCHDFLE 1078
Query: 529 CANDP 533
C N P
Sbjct: 1079 CQNSP 1083
Score = 207 bits (505), Expect = 9e-53
Identities = 132/362 (36%), Positives = 167/362 (46%), Gaps = 48/362 (13%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC----DCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
++NEC C G C N LG F C C PGY K+ C DV+EC + C
Sbjct: 719 DINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL--KDGECEDVDECAMGTHTCQ 776
Query: 173 DGD-CHNTEGSFTCH----CRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFR 226
G C NT+GSF C C G+ D CVDI+EC CR G C+NT GS+
Sbjct: 777 PGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGSYT 835
Query: 227 CE-----CGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTV 280
C+ C G + D C D++EC C G C N G+Y+C C G+ +
Sbjct: 836 CQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAF 895
Query: 281 KSHXXXXXXXXXXXXR-CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
R CQH+C NT GSY C+C G+ L ADG+ C D++EC A+ C
Sbjct: 896 GRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE--AQRCS 953
Query: 340 GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIP 399
+C N GSY C C G + G TC DIDECA
Sbjct: 954 Q-ECANIYGSYQCYCRQGYQLAEDGH--TCTDIDECAQGAGI------------------ 992
Query: 400 ELCGAGSCHNTIGSFVCQCPD-GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
LC C N GS+ C CP+ GY++ G +C D DEC LGT +C A C N+ GSF
Sbjct: 993 -LC-TFRCLNVPGSYQCACPEQGYTMTAN-GRSCKDVDECALGTHNCSEAETCHNIQGSF 1049
Query: 459 QC 460
+C
Sbjct: 1050 RC 1051
Score = 190 bits (463), Expect = 1e-47
Identities = 149/471 (31%), Positives = 200/471 (42%), Gaps = 78/471 (16%)
Query: 120 NECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
+EC PG LC H C N +G + C CFPG+ TC +G
Sbjct: 606 DECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRP------------EGHPPQ 652
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDE---CADNDALCRGGRCVNTAGSFRCECGHGMEL 235
E + + + I + + + C DN C+ C GS C C G +
Sbjct: 653 PEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGP-CKQV-CSTVGGSAICSCFPGYAI 710
Query: 236 APDRLSCKDIDECSITSGICSNGA-CENQMGTYQC----VCDEGYAQSTVKSHXXXXXXX 290
D +SC+DI+EC CS G C N +G++ C C+ GYA +
Sbjct: 711 MADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAM 770
Query: 291 XXXXXRCQHSCVNTPGSYHCT----CREGWHLRADGRSCRDIDECAGGARPCGGG-QCRN 345
+ C NT GS++C C +G+ +G +C DI+EC + PC G C N
Sbjct: 771 GTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCIN 829
Query: 346 TVGSYTCT-----CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPE 400
TVGSYTC C G S GAK C D++EC +
Sbjct: 830 TVGSYTCQRNPLICARGYHASDDGAK--CVDVNECETGVHR------------------- 868
Query: 401 LCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC--ELGTCDCHPAADCINLPGS 457
CG G CHN GS+ C C G+ + G C D +EC G H C N GS
Sbjct: 869 -CGEGQVCHNLPGSYRCDCKAGFQ-RDAFGRGCIDVNECWASPGRLCQHT---CENTLGS 923
Query: 458 FQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
++C C G+ DG CEDV+EC C CAN GS++C C GY+ G
Sbjct: 924 YRCSCASGFLLAADGKRCEDVNECEAQR--CSQE--CANIYGSYQCYCRQGYQLAEDG-- 977
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDC-DVGFTRAADGRSC 565
++C DIDECA + C N PG Y+C C + G+T A+GRSC
Sbjct: 978 -----HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
Score = 173 bits (422), Expect = 1e-42
Identities = 138/426 (32%), Positives = 180/426 (42%), Gaps = 69/426 (16%)
Query: 160 DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCV 219
D +EC ++ G C NT GS+ C C PG+ D + C +A
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA--- 660
Query: 220 NTAGSFRCECGHGMEL-APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQS 278
F + + L P +CKD +G C C G+ C C GYA
Sbjct: 661 -LKSEFSQVASNTIPLPLPQPNTCKD-------NGPCKQ-VCSTVGGSAICSCFPGYAIM 711
Query: 279 TVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHC----TCREGWHLRADGRSCRDIDECA 332
C CVNT GS+HC TC G+ L+ DG C D+DECA
Sbjct: 712 ADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DG-ECEDVDECA 769
Query: 333 GGARPCGGG-QCRNTVGSYTC----TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
G C G C+NT GS+ C C DG + G C DI+EC L
Sbjct: 770 MGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG---NCVDINECTSL--------- 817
Query: 388 DELQKSVDPQIPELCGAG-SCHNTIGSFVCQ-----CPDGYSVKPEQGPACTDDDECELG 441
E C G SC NT+GS+ CQ C GY + G C D +ECE G
Sbjct: 818 -----------SEPCRPGFSCINTVGSYTCQRNPLICARGYHAS-DDGAKCVDVNECETG 865
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGD--GATCEDVDECLTNNGGCHPRATCANTDGSF 499
C C NLPGS++C C+ G++ D G C DV+EC + G + TC NT GS+
Sbjct: 866 VHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL-CQHTCENTLGSY 924
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRA 559
RC C +G+ G R C D++EC + C C+N G Y+C C G+ A
Sbjct: 925 RCSCASGFLLAADGKR-------CEDVNEC--EAQRCSQ-ECANIYGSYQCYCRQGYQLA 974
Query: 560 ADGRSC 565
DG +C
Sbjct: 975 EDGHTC 980
Score = 157 bits (382), Expect = 7e-38
Identities = 102/300 (34%), Positives = 135/300 (45%), Gaps = 45/300 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
CQH C+NT GSYHC C G+ L+ DGR+CR G P + S
Sbjct: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCRP-----EGHPPQPEAPQEPALKSEFSQVAS 670
Query: 357 GLVPSAAGAKPTCQDIDECADLISTI------------IMMSVDELQKSVDPQIPEL--C 402
+P TC+D C + ST+ +M+ + ++ + +L C
Sbjct: 671 NTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTC 730
Query: 403 GAGS-CHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
G C NT+GSF C C GY++K + C D DEC +GT C P C N GS
Sbjct: 731 SRGEHCVNTLGSFHCYKALTCEPGYALKDGE---CEDVDECAMGTHTCQPGFLCQNTKGS 787
Query: 458 FQC----RCRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSFRC-----LCDTGY 507
F C RC DG+ D C D++EC + + C P +C NT GS+ C +C GY
Sbjct: 788 FYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGY 847
Query: 508 KGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTRAADGRSCL 566
G + CVD++EC C G C N PG Y CDC GF R A GR C+
Sbjct: 848 HASDDGAK-------CVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 900
Score = 137 bits (332), Expect = 8e-32
Identities = 70/198 (35%), Positives = 96/198 (48%), Gaps = 7/198 (3%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++VNEC CG G+ C NL G + CDC G+++D+ C+DVNEC G
Sbjct: 857 VDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT 916
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C NT GS+ C C G+ K C D++EC +A C N GS++C C G +L
Sbjct: 917 CENTLGSYRCSCASGFLLAADGKRCEDVNEC---EAQRCSQECANIYGSYQCYCRQGYQL 973
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVC-DEGYAQSTVKSHXXXXXXXXXXX 294
A D +C DIDEC+ +GI C N G+YQC C ++GY +
Sbjct: 974 AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGT 1033
Query: 295 XRCQ--HSCVNTPGSYHC 310
C +C N GS+ C
Sbjct: 1034 HNCSEAETCHNIQGSFRC 1051
Score = 129 bits (311), Expect = 3e-29
Identities = 65/167 (38%), Positives = 89/167 (53%), Gaps = 10/167 (5%)
Query: 117 MEVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++VNEC A PG LC H C N LG + C C G+ + C DVNECE C +
Sbjct: 900 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQ-E 955
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHGME 234
C N GS+ C+CR GY+ + C DIDECA + RC+N GS++C C G
Sbjct: 956 CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYT 1015
Query: 235 LAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCV---CDEGYAQ 277
+ + SCKD+DEC++ + CS C N G+++C+ C Y Q
Sbjct: 1016 MTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQ 1062
>BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein.
Length = 1184
Score = 231 bits (565), Expect = 5e-60
Identities = 154/425 (36%), Positives = 197/425 (46%), Gaps = 59/425 (13%)
Query: 134 CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----CR 188
C + G C CFPGY + +C D+NEC C G+ C NT GSF C+ C
Sbjct: 693 CSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCE 752
Query: 189 PGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRCE----CGHGMELAPDRLSCK 243
PGY D C D+DECA C+ G C NT GSF C+ C G P+ +C
Sbjct: 753 PGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCV 809
Query: 244 DIDECSITSGICSNG-ACENQMGTYQC-----VCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
DI+EC+ S C G +C N +G+Y C +C GY S + RC
Sbjct: 810 DINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRC 869
Query: 298 QHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDEC-AGGARPCGGGQCRNTVGSYTCTC 354
C N PGSY C C+ G+ A GR C D++EC A R C C NT+GSY C+C
Sbjct: 870 GEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSC 928
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
G + +A G + C+D++EC E Q+ C C N GS+
Sbjct: 929 ASGFLLAADGKR--CEDVNEC-------------EAQR---------CSQ-ECANIYGSY 963
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD-GWR--GDGA 471
C C GY + E G CTD DEC G C+N+PGS+QC C + G+ +G
Sbjct: 964 QCYCRQGYQLA-EDGHTCTDIDECAQGA-GILCTFRCLNVPGSYQCACPEQGYTMTANGR 1021
Query: 472 TCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLRTVCCVYSCVDIDE 528
+C+DVDEC C TC N GSFRCL C Y +T C +C D E
Sbjct: 1022 SCKDVDECALGTHNCSEAETCHNIQGSFRCLRLECPPNYVQVS---KTKCERTTCHDFLE 1078
Query: 529 CANDP 533
C N P
Sbjct: 1079 CQNSP 1083
Score = 207 bits (505), Expect = 9e-53
Identities = 132/362 (36%), Positives = 167/362 (46%), Gaps = 48/362 (13%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC----DCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
++NEC C G C N LG F C C PGY K+ C DV+EC + C
Sbjct: 719 DINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL--KDGECEDVDECAMGTHTCQ 776
Query: 173 DGD-CHNTEGSFTCH----CRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFR 226
G C NT+GSF C C G+ D CVDI+EC CR G C+NT GS+
Sbjct: 777 PGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGSYT 835
Query: 227 CE-----CGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTV 280
C+ C G + D C D++EC C G C N G+Y+C C G+ +
Sbjct: 836 CQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAF 895
Query: 281 KSHXXXXXXXXXXXXR-CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
R CQH+C NT GSY C+C G+ L ADG+ C D++EC A+ C
Sbjct: 896 GRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE--AQRCS 953
Query: 340 GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIP 399
+C N GSY C C G + G TC DIDECA
Sbjct: 954 Q-ECANIYGSYQCYCRQGYQLAEDGH--TCTDIDECAQGAGI------------------ 992
Query: 400 ELCGAGSCHNTIGSFVCQCPD-GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
LC C N GS+ C CP+ GY++ G +C D DEC LGT +C A C N+ GSF
Sbjct: 993 -LC-TFRCLNVPGSYQCACPEQGYTMTAN-GRSCKDVDECALGTHNCSEAETCHNIQGSF 1049
Query: 459 QC 460
+C
Sbjct: 1050 RC 1051
Score = 190 bits (463), Expect = 1e-47
Identities = 149/471 (31%), Positives = 200/471 (42%), Gaps = 78/471 (16%)
Query: 120 NECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
+EC PG LC H C N +G + C CFPG+ TC +G
Sbjct: 606 DECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRP------------EGHPPQ 652
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDE---CADNDALCRGGRCVNTAGSFRCECGHGMEL 235
E + + + I + + + C DN C+ C GS C C G +
Sbjct: 653 PEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGP-CKQV-CSTVGGSAICSCFPGYAI 710
Query: 236 APDRLSCKDIDECSITSGICSNGA-CENQMGTYQC----VCDEGYAQSTVKSHXXXXXXX 290
D +SC+DI+EC CS G C N +G++ C C+ GYA +
Sbjct: 711 MADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAM 770
Query: 291 XXXXXRCQHSCVNTPGSYHCT----CREGWHLRADGRSCRDIDECAGGARPCGGG-QCRN 345
+ C NT GS++C C +G+ +G +C DI+EC + PC G C N
Sbjct: 771 GTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCIN 829
Query: 346 TVGSYTCT-----CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPE 400
TVGSYTC C G S GAK C D++EC +
Sbjct: 830 TVGSYTCQRNPLICARGYHASDDGAK--CVDVNECETGVHR------------------- 868
Query: 401 LCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC--ELGTCDCHPAADCINLPGS 457
CG G CHN GS+ C C G+ + G C D +EC G H C N GS
Sbjct: 869 -CGEGQVCHNLPGSYRCDCKAGFQ-RDAFGRGCIDVNECWASPGRLCQHT---CENTLGS 923
Query: 458 FQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
++C C G+ DG CEDV+EC C CAN GS++C C GY+ G
Sbjct: 924 YRCSCASGFLLAADGKRCEDVNECEAQR--CSQE--CANIYGSYQCYCRQGYQLAEDG-- 977
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDC-DVGFTRAADGRSC 565
++C DIDECA + C N PG Y+C C + G+T A+GRSC
Sbjct: 978 -----HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
Score = 173 bits (422), Expect = 1e-42
Identities = 138/426 (32%), Positives = 180/426 (42%), Gaps = 69/426 (16%)
Query: 160 DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCV 219
D +EC ++ G C NT GS+ C C PG+ D + C +A
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA--- 660
Query: 220 NTAGSFRCECGHGMEL-APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQS 278
F + + L P +CKD +G C C G+ C C GYA
Sbjct: 661 -LKSEFSQVASNTIPLPLPQPNTCKD-------NGPCKQ-VCSTVGGSAICSCFPGYAIM 711
Query: 279 TVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHC----TCREGWHLRADGRSCRDIDECA 332
C CVNT GS+HC TC G+ L+ DG C D+DECA
Sbjct: 712 ADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DG-ECEDVDECA 769
Query: 333 GGARPCGGG-QCRNTVGSYTC----TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSV 387
G C G C+NT GS+ C C DG + G C DI+EC L
Sbjct: 770 MGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG---NCVDINECTSL--------- 817
Query: 388 DELQKSVDPQIPELCGAG-SCHNTIGSFVCQ-----CPDGYSVKPEQGPACTDDDECELG 441
E C G SC NT+GS+ CQ C GY + G C D +ECE G
Sbjct: 818 -----------SEPCRPGFSCINTVGSYTCQRNPLICARGYHAS-DDGAKCVDVNECETG 865
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGD--GATCEDVDECLTNNGGCHPRATCANTDGSF 499
C C NLPGS++C C+ G++ D G C DV+EC + G + TC NT GS+
Sbjct: 866 VHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL-CQHTCENTLGSY 924
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRA 559
RC C +G+ G R C D++EC + C C+N G Y+C C G+ A
Sbjct: 925 RCSCASGFLLAADGKR-------CEDVNEC--EAQRCSQ-ECANIYGSYQCYCRQGYQLA 974
Query: 560 ADGRSC 565
DG +C
Sbjct: 975 EDGHTC 980
Score = 157 bits (382), Expect = 7e-38
Identities = 102/300 (34%), Positives = 135/300 (45%), Gaps = 45/300 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
CQH C+NT GSYHC C G+ L+ DGR+CR G P + S
Sbjct: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCRP-----EGHPPQPEAPQEPALKSEFSQVAS 670
Query: 357 GLVPSAAGAKPTCQDIDECADLISTI------------IMMSVDELQKSVDPQIPEL--C 402
+P TC+D C + ST+ +M+ + ++ + +L C
Sbjct: 671 NTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTC 730
Query: 403 GAGS-CHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
G C NT+GSF C C GY++K + C D DEC +GT C P C N GS
Sbjct: 731 SRGEHCVNTLGSFHCYKALTCEPGYALKDGE---CEDVDECAMGTHTCQPGFLCQNTKGS 787
Query: 458 FQC----RCRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSFRC-----LCDTGY 507
F C RC DG+ D C D++EC + + C P +C NT GS+ C +C GY
Sbjct: 788 FYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGY 847
Query: 508 KGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTRAADGRSCL 566
G + CVD++EC C G C N PG Y CDC GF R A GR C+
Sbjct: 848 HASDDGAK-------CVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 900
Score = 137 bits (332), Expect = 8e-32
Identities = 70/198 (35%), Positives = 96/198 (48%), Gaps = 7/198 (3%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++VNEC CG G+ C NL G + CDC G+++D+ C+DVNEC G
Sbjct: 857 VDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT 916
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C NT GS+ C C G+ K C D++EC +A C N GS++C C G +L
Sbjct: 917 CENTLGSYRCSCASGFLLAADGKRCEDVNEC---EAQRCSQECANIYGSYQCYCRQGYQL 973
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVC-DEGYAQSTVKSHXXXXXXXXXXX 294
A D +C DIDEC+ +GI C N G+YQC C ++GY +
Sbjct: 974 AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGT 1033
Query: 295 XRCQ--HSCVNTPGSYHC 310
C +C N GS+ C
Sbjct: 1034 HNCSEAETCHNIQGSFRC 1051
Score = 129 bits (311), Expect = 3e-29
Identities = 65/167 (38%), Positives = 89/167 (53%), Gaps = 10/167 (5%)
Query: 117 MEVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++VNEC A PG LC H C N LG + C C G+ + C DVNECE C +
Sbjct: 900 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQ-E 955
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHGME 234
C N GS+ C+CR GY+ + C DIDECA + RC+N GS++C C G
Sbjct: 956 CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYT 1015
Query: 235 LAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCV---CDEGYAQ 277
+ + SCKD+DEC++ + CS C N G+++C+ C Y Q
Sbjct: 1016 MTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRLECPPNYVQ 1062
>U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor
protein.
Length = 956
Score = 227 bits (554), Expect = 1e-58
Identities = 144/446 (32%), Positives = 198/446 (44%), Gaps = 43/446 (9%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C+ C H C N+ G + C C GY +S TC + C + D C + C N G
Sbjct: 242 CSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC-EQLCVNVPG 299
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
SF C C GY + K CV +D CA + C CVN GS+ C+C G L PD+ +
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCE-HECVNADGSYLCQCHEGFALNPDKKT 358
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C ID C+ ++ C + C N +Y C C +G+ + K C+H C
Sbjct: 359 CTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHEC 417
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
VN SY+C C G+ L +G++C +D CA C C NT S+ C C++G + +
Sbjct: 418 VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGC-EQLCLNTEDSFVCQCSEGFLIN 476
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
TC +D C L+S C SC N SF CQCP+G
Sbjct: 477 E--DLKTCSRVDYC--LLS------------------DHGC-EYSCVNMDRSFACQCPEG 513
Query: 422 YSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVDEC 479
+ ++ + G C D C LG C + C++ SF C+C +G+ R DG TC D C
Sbjct: 514 HVLRSD-GKTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVC 570
Query: 480 LTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG 539
+ GC C N+D S+ C C G++ G R C D C + CE+
Sbjct: 571 QAIDHGC--EHICVNSDDSYTCECLVGFRLAEDGKR-------CRRKDVCKSTHHGCEH- 620
Query: 540 HCSNTPGGYECDCDVGFTRAADGRSC 565
C N Y C C GF A DGR C
Sbjct: 621 ICVNNGNSYICKCSEGFVLAEDGRRC 646
Score = 200 bits (489), Expect = 8e-51
Identities = 134/397 (33%), Positives = 174/397 (43%), Gaps = 45/397 (11%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C+ GY + C D CA D C CVN GSF C+C G L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
A D C +D C+ + C + C N G+Y C C EG+A + K
Sbjct: 312 AEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNH 370
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
CQH CVNT SY C C +G+ L D ++CR I+ CA C +C N SY C C
Sbjct: 371 GCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCH 429
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G G TC +D CA D +LC NT SFV
Sbjct: 430 RGYTLDPNGK--TCSRVDHCAQQ----------------DHGCEQLC-----LNTEDSFV 466
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATC 473
CQC +G+ + E C+ D C L C + C+N+ SF C+C +G R DG TC
Sbjct: 467 CQCSEGFLIN-EDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTC 523
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY--KGDGYGLRTVCCVYSCVDIDECAN 531
+D C + GC +C +++ SF C C GY + DG +C D C
Sbjct: 524 AKLDSCALGDHGCEH--SCVSSEDSFVCQCFEGYILREDGK---------TCRRKDVCQA 572
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
CE+ C N+ Y C+C VGF A DG+ C K
Sbjct: 573 IDHGCEH-ICVNSDDSYTCECLVGFRLAEDGKRCRRK 608
Score = 159 bits (386), Expect = 2e-38
Identities = 102/362 (28%), Positives = 155/362 (42%), Gaps = 33/362 (9%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
V+ CA+ C H C N G + C C G+ + TC ++ C + C +C N
Sbjct: 321 VDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGC-QHECVN 378
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
T+ S++CHC G+ + K C I+ CA N C CVN S+ C C G L P+
Sbjct: 379 TDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPN 437
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
+C +D C+ C C N ++ C C EG+ + C+
Sbjct: 438 GKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCE 496
Query: 299 HSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL 358
+SCVN S+ C C EG LR+DG++C +D CA G C C ++ S+ C C +G
Sbjct: 497 YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGC-EHSCVSSEDSFVCQCFEGY 555
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
+ G TC+ D C +++D + C N+ S+ C+C
Sbjct: 556 ILREDG--KTCRRKDVC----------------QAIDHGCEHI-----CVNSDDSYTCEC 592
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDV 476
G+ + E G C D C+ C C+N S+ C+C +G+ DG C+
Sbjct: 593 LVGFRL-AEDGKRCRRKDVCKSTHHGCEHI--CVNNGNSYICKCSEGFVLAEDGRRCKKC 649
Query: 477 DE 478
E
Sbjct: 650 TE 651
Score = 146 bits (353), Expect = 2e-34
Identities = 80/258 (31%), Positives = 117/258 (45%), Gaps = 7/258 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++ CA+ C H C N ++C C G+ + TC +N C + C + +C
Sbjct: 361 KIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC-EHECV 418
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N E S+ C C GY D K C +D CA D C C+NT SF C+C G +
Sbjct: 419 NMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINE 477
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
D +C +D C ++ C +C N ++ C C EG+ + C
Sbjct: 478 DLKTCSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGC 536
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+HSCV++ S+ C C EG+ LR DG++CR D C C C N+ SYTC C G
Sbjct: 537 EHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLVG 595
Query: 358 LVPSAAGAKPTCQDIDEC 375
+ G + C+ D C
Sbjct: 596 FRLAEDGKR--CRRKDVC 611
>BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein.
Length = 715
Score = 225 bits (551), Expect = 2e-58
Identities = 144/446 (32%), Positives = 197/446 (44%), Gaps = 43/446 (9%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C+ C H C N+ G + C C GY +S TC + C + D C + C N G
Sbjct: 1 CSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC-EQLCVNVPG 58
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
SF C C GY + K CV +D CA + C CVN GS+ C+C G L PD +
Sbjct: 59 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCE-HECVNADGSYLCQCHEGFALNPDEKT 117
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C ID C+ ++ C + C N +Y C C +G+ + K C+H C
Sbjct: 118 CTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHEC 176
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
VN SY+C C G+ L +G++C +D CA C C NT S+ C C++G + +
Sbjct: 177 VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGC-EQLCLNTEDSFVCQCSEGFLIN 235
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
TC +D C L+S C SC N SF CQCP+G
Sbjct: 236 E--DLKTCSRVDYC--LLS------------------DHGC-EYSCVNMDRSFACQCPEG 272
Query: 422 YSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVDEC 479
+ ++ + G C D C LG C + C++ SF C+C +G+ R DG TC D C
Sbjct: 273 HVLRSD-GKTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVC 329
Query: 480 LTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG 539
+ GC C N+D S+ C C G++ G R C D C + CE+
Sbjct: 330 QAIDHGC--EHICVNSDDSYTCECLEGFRLAEDGKR-------CRRKDVCKSTHHGCEH- 379
Query: 540 HCSNTPGGYECDCDVGFTRAADGRSC 565
C N Y C C GF A DGR C
Sbjct: 380 ICVNNGNSYICKCSEGFVLAEDGRRC 405
Score = 196 bits (479), Expect = 1e-49
Identities = 132/397 (33%), Positives = 173/397 (43%), Gaps = 45/397 (11%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C+ GY + C D CA D C CVN GSF C+C G L
Sbjct: 12 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 70
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
A D C +D C+ + C + C N G+Y C C EG+A + +
Sbjct: 71 AEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNH 129
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
CQH CVNT SY C C +G+ L D ++CR I+ CA C +C N SY C C
Sbjct: 130 GCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCH 188
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G G TC +D CA D +LC NT SFV
Sbjct: 189 RGYTLDPNGK--TCSRVDHCAQQ----------------DHGCEQLC-----LNTEDSFV 225
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATC 473
CQC +G+ + E C+ D C L C + C+N+ SF C+C +G R DG TC
Sbjct: 226 CQCSEGFLIN-EDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTC 282
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY--KGDGYGLRTVCCVYSCVDIDECAN 531
+D C + GC +C +++ SF C C GY + DG +C D C
Sbjct: 283 AKLDSCALGDHGCEH--SCVSSEDSFVCQCFEGYILREDGK---------TCRRKDVCQA 331
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
CE+ C N+ Y C+C GF A DG+ C K
Sbjct: 332 IDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRK 367
Score = 161 bits (391), Expect = 6e-39
Identities = 102/362 (28%), Positives = 156/362 (43%), Gaps = 33/362 (9%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
V+ CA+ C H C N G + C C G+ + TC ++ C + C +C N
Sbjct: 80 VDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHGC-QHECVN 137
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
T+ S++CHC G+ + K C I+ CA N C CVN S+ C C G L P+
Sbjct: 138 TDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPN 196
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
+C +D C+ C C N ++ C C EG+ + C+
Sbjct: 197 GKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCE 255
Query: 299 HSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL 358
+SCVN S+ C C EG LR+DG++C +D CA G C C ++ S+ C C +G
Sbjct: 256 YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGC-EHSCVSSEDSFVCQCFEGY 314
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
+ G TC+ D C +++D + C N+ S+ C+C
Sbjct: 315 ILREDG--KTCRRKDVC----------------QAIDHGCEHI-----CVNSDDSYTCEC 351
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDV 476
+G+ + E G C D C+ C C+N S+ C+C +G+ DG C+
Sbjct: 352 LEGFRL-AEDGKRCRRKDVCKSTHHGCEHI--CVNNGNSYICKCSEGFVLAEDGRRCKKC 408
Query: 477 DE 478
E
Sbjct: 409 TE 410
Score = 148 bits (358), Expect = 6e-35
Identities = 80/258 (31%), Positives = 118/258 (45%), Gaps = 7/258 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++ CA+ C H C N ++C C G+ + TC +N C + C + +C
Sbjct: 120 KIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC-EHECV 177
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N E S+ C C GY D K C +D CA D C C+NT SF C+C G +
Sbjct: 178 NMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINE 236
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
D +C +D C ++ C +C N ++ C C EG+ + C
Sbjct: 237 DLKTCSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGC 295
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+HSCV++ S+ C C EG+ LR DG++CR D C C C N+ SYTC C +G
Sbjct: 296 EHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEG 354
Query: 358 LVPSAAGAKPTCQDIDEC 375
+ G + C+ D C
Sbjct: 355 FRLAEDGKR--CRRKDVC 370
>BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein.
Length = 937
Score = 225 bits (551), Expect = 2e-58
Identities = 144/446 (32%), Positives = 197/446 (44%), Gaps = 43/446 (9%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C+ C H C N+ G + C C GY +S TC + C + D C + C N G
Sbjct: 242 CSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC-EQLCVNVPG 299
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
SF C C GY + K CV +D CA + C CVN GS+ C+C G L PD +
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCE-HECVNADGSYLCQCHEGFALNPDEKT 358
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C ID C+ ++ C + C N +Y C C +G+ + K C+H C
Sbjct: 359 CTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHEC 417
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
VN SY+C C G+ L +G++C +D CA C C NT S+ C C++G + +
Sbjct: 418 VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGC-EQLCLNTEDSFVCQCSEGFLIN 476
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
TC +D C L+S C SC N SF CQCP+G
Sbjct: 477 E--DLKTCSRVDYC--LLS------------------DHGC-EYSCVNMDRSFACQCPEG 513
Query: 422 YSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVDEC 479
+ ++ + G C D C LG C + C++ SF C+C +G+ R DG TC D C
Sbjct: 514 HVLRSD-GKTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVC 570
Query: 480 LTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG 539
+ GC C N+D S+ C C G++ G R C D C + CE+
Sbjct: 571 QAIDHGC--EHICVNSDDSYTCECLEGFRLAEDGKR-------CRRKDVCKSTHHGCEH- 620
Query: 540 HCSNTPGGYECDCDVGFTRAADGRSC 565
C N Y C C GF A DGR C
Sbjct: 621 ICVNNGNSYICKCSEGFVLAEDGRRC 646
Score = 196 bits (479), Expect = 1e-49
Identities = 132/397 (33%), Positives = 173/397 (43%), Gaps = 45/397 (11%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C+ GY + C D CA D C CVN GSF C+C G L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
A D C +D C+ + C + C N G+Y C C EG+A + +
Sbjct: 312 AEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNH 370
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
CQH CVNT SY C C +G+ L D ++CR I+ CA C +C N SY C C
Sbjct: 371 GCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCH 429
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G G TC +D CA D +LC NT SFV
Sbjct: 430 RGYTLDPNGK--TCSRVDHCAQQ----------------DHGCEQLC-----LNTEDSFV 466
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATC 473
CQC +G+ + E C+ D C L C + C+N+ SF C+C +G R DG TC
Sbjct: 467 CQCSEGFLIN-EDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTC 523
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY--KGDGYGLRTVCCVYSCVDIDECAN 531
+D C + GC +C +++ SF C C GY + DG +C D C
Sbjct: 524 AKLDSCALGDHGCEH--SCVSSEDSFVCQCFEGYILREDGK---------TCRRKDVCQA 572
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
CE+ C N+ Y C+C GF A DG+ C K
Sbjct: 573 IDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRK 608
Score = 161 bits (391), Expect = 6e-39
Identities = 102/362 (28%), Positives = 156/362 (43%), Gaps = 33/362 (9%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
V+ CA+ C H C N G + C C G+ + TC ++ C + C +C N
Sbjct: 321 VDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHGC-QHECVN 378
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
T+ S++CHC G+ + K C I+ CA N C CVN S+ C C G L P+
Sbjct: 379 TDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPN 437
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
+C +D C+ C C N ++ C C EG+ + C+
Sbjct: 438 GKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCE 496
Query: 299 HSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL 358
+SCVN S+ C C EG LR+DG++C +D CA G C C ++ S+ C C +G
Sbjct: 497 YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGC-EHSCVSSEDSFVCQCFEGY 555
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
+ G TC+ D C +++D + C N+ S+ C+C
Sbjct: 556 ILREDG--KTCRRKDVC----------------QAIDHGCEHI-----CVNSDDSYTCEC 592
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDV 476
+G+ + E G C D C+ C C+N S+ C+C +G+ DG C+
Sbjct: 593 LEGFRL-AEDGKRCRRKDVCKSTHHGCEHI--CVNNGNSYICKCSEGFVLAEDGRRCKKC 649
Query: 477 DE 478
E
Sbjct: 650 TE 651
Score = 148 bits (358), Expect = 6e-35
Identities = 80/258 (31%), Positives = 118/258 (45%), Gaps = 7/258 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++ CA+ C H C N ++C C G+ + TC +N C + C + +C
Sbjct: 361 KIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC-EHECV 418
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N E S+ C C GY D K C +D CA D C C+NT SF C+C G +
Sbjct: 419 NMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINE 477
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
D +C +D C ++ C +C N ++ C C EG+ + C
Sbjct: 478 DLKTCSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGC 536
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+HSCV++ S+ C C EG+ LR DG++CR D C C C N+ SYTC C +G
Sbjct: 537 EHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEG 595
Query: 358 LVPSAAGAKPTCQDIDEC 375
+ G + C+ D C
Sbjct: 596 FRLAEDGKR--CRRKDVC 611
>AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein
protein.
Length = 1016
Score = 225 bits (551), Expect = 2e-58
Identities = 144/446 (32%), Positives = 197/446 (44%), Gaps = 43/446 (9%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C+ C H C N+ G + C C GY +S TC + C + D C + C N G
Sbjct: 302 CSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC-EQLCVNVPG 359
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
SF C C GY + K CV +D CA + C CVN GS+ C+C G L PD +
Sbjct: 360 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCE-HECVNADGSYLCQCHEGFALNPDEKT 418
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C ID C+ ++ C + C N +Y C C +G+ + K C+H C
Sbjct: 419 CTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHEC 477
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
VN SY+C C G+ L +G++C +D CA C C NT S+ C C++G + +
Sbjct: 478 VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGC-EQLCLNTEDSFVCQCSEGFLIN 536
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
TC +D C L+S C SC N SF CQCP+G
Sbjct: 537 E--DLKTCSRVDYC--LLS------------------DHGC-EYSCVNMDRSFACQCPEG 573
Query: 422 YSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVDEC 479
+ ++ + G C D C LG C + C++ SF C+C +G+ R DG TC D C
Sbjct: 574 HVLRSD-GKTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVC 630
Query: 480 LTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG 539
+ GC C N+D S+ C C G++ G R C D C + CE+
Sbjct: 631 QAIDHGC--EHICVNSDDSYTCECLEGFRLAEDGKR-------CRRKDVCKSTHHGCEH- 680
Query: 540 HCSNTPGGYECDCDVGFTRAADGRSC 565
C N Y C C GF A DGR C
Sbjct: 681 ICVNNGNSYICKCSEGFVLAEDGRRC 706
Score = 196 bits (479), Expect = 1e-49
Identities = 132/397 (33%), Positives = 173/397 (43%), Gaps = 45/397 (11%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C+ GY + C D CA D C CVN GSF C+C G L
Sbjct: 313 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 371
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
A D C +D C+ + C + C N G+Y C C EG+A + +
Sbjct: 372 AEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNH 430
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
CQH CVNT SY C C +G+ L D ++CR I+ CA C +C N SY C C
Sbjct: 431 GCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCH 489
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G G TC +D CA D +LC NT SFV
Sbjct: 490 RGYTLDPNGK--TCSRVDHCAQQ----------------DHGCEQLC-----LNTEDSFV 526
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATC 473
CQC +G+ + E C+ D C L C + C+N+ SF C+C +G R DG TC
Sbjct: 527 CQCSEGFLIN-EDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTC 583
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY--KGDGYGLRTVCCVYSCVDIDECAN 531
+D C + GC +C +++ SF C C GY + DG +C D C
Sbjct: 584 AKLDSCALGDHGCEH--SCVSSEDSFVCQCFEGYILREDGK---------TCRRKDVCQA 632
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
CE+ C N+ Y C+C GF A DG+ C K
Sbjct: 633 IDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRK 668
Score = 161 bits (391), Expect = 6e-39
Identities = 102/362 (28%), Positives = 156/362 (43%), Gaps = 33/362 (9%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
V+ CA+ C H C N G + C C G+ + TC ++ C + C +C N
Sbjct: 381 VDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHGC-QHECVN 438
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
T+ S++CHC G+ + K C I+ CA N C CVN S+ C C G L P+
Sbjct: 439 TDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPN 497
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
+C +D C+ C C N ++ C C EG+ + C+
Sbjct: 498 GKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCE 556
Query: 299 HSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL 358
+SCVN S+ C C EG LR+DG++C +D CA G C C ++ S+ C C +G
Sbjct: 557 YSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGC-EHSCVSSEDSFVCQCFEGY 615
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
+ G TC+ D C +++D + C N+ S+ C+C
Sbjct: 616 ILREDG--KTCRRKDVC----------------QAIDHGCEHI-----CVNSDDSYTCEC 652
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDV 476
+G+ + E G C D C+ C C+N S+ C+C +G+ DG C+
Sbjct: 653 LEGFRL-AEDGKRCRRKDVCKSTHHGCEHI--CVNNGNSYICKCSEGFVLAEDGRRCKKC 709
Query: 477 DE 478
E
Sbjct: 710 TE 711
Score = 148 bits (358), Expect = 6e-35
Identities = 80/258 (31%), Positives = 118/258 (45%), Gaps = 7/258 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++ CA+ C H C N ++C C G+ + TC +N C + C + +C
Sbjct: 421 KIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC-EHECV 478
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N E S+ C C GY D K C +D CA D C C+NT SF C+C G +
Sbjct: 479 NMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINE 537
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
D +C +D C ++ C +C N ++ C C EG+ + C
Sbjct: 538 DLKTCSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGC 596
Query: 298 QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDG 357
+HSCV++ S+ C C EG+ LR DG++CR D C C C N+ SYTC C +G
Sbjct: 597 EHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEG 655
Query: 358 LVPSAAGAKPTCQDIDEC 375
+ G + C+ D C
Sbjct: 656 FRLAEDGKR--CRRKDVC 671
>BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein.
Length = 683
Score = 225 bits (549), Expect = 4e-58
Identities = 143/413 (34%), Positives = 190/413 (46%), Gaps = 60/413 (14%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCE----CG 230
C +T C C GY+ C D++EC CR G C+NT GSFRC+ CG
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG 249
Query: 231 HGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQC----VCDEGYAQSTVKSHXX 285
G EL D SCKDIDEC C + C+N +G+++C C G+ Q + +
Sbjct: 250 TGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL-GNCI 307
Query: 286 XXXXXXXXXXRCQ--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPC 338
C H+C+NT GSY C C G+HL +G C D+DECA A PC
Sbjct: 308 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Query: 339 GGG-QCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
G G +C N+ GS+ C C G G C D++EC
Sbjct: 368 GKGHRCVNSPGSFRCECKTGYYFD--GISRMCVDVNECQRYPG----------------- 408
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
LCG C NT+GS++C C G+ + + G +C D +EC C + +C N+ GS
Sbjct: 409 --RLCGH-KCENTLGSYLCSCSVGFRLSVD-GRSCEDINECSSSPC----SQECANVYGS 460
Query: 458 FQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+QC CR G++ DG TCED+DEC GG C N GSF+C C + G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS------GY 514
Query: 515 RTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYEC---DCDVGFTRAADGR 563
R +C DIDEC C N C N GG+ C +C + R+A R
Sbjct: 515 RLAPNGSNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATR 567
Score = 214 bits (523), Expect = 6e-55
Identities = 151/435 (34%), Positives = 192/435 (44%), Gaps = 56/435 (12%)
Query: 133 RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----C 187
+CR+ C CF GY+ S +C DVNEC C G+ C NT GSF C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC----ECGHGMELAPDRL-S 241
GY+ + C DIDEC C C NT GSFRC +C G D L +
Sbjct: 249 GTGYELTE-DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG--FIQDALGN 305
Query: 242 CKDIDECSITSGICSNG-ACENQMGTYQCV-----CDEGYAQSTVKSHXXXXXXXXXXXX 295
C DI+EC S C G C N G+Y C C GY + +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H CVN+PGS+ C C+ G++ R C D++EC G +C NT+GSY C+
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C+ G S G +C+DI+EC S P C + C N GS
Sbjct: 426 CSVGFRLSVDGR--SCEDINEC-----------------SSSP-----C-SQECANVYGS 460
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDGWR--GDG 470
+ C C GY + G C D DEC L T + CIN+PGSFQC C G+R +G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG 520
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLRTVCCVYSCVDID 527
+ C+D+DEC+T C TC N G FRCL C Y+ T C C +
Sbjct: 521 SNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA---ATRCERLPCHENR 577
Query: 528 ECANDPTLCENGHCS 542
EC+ P H S
Sbjct: 578 ECSKLPLRITYYHLS 592
Score = 180 bits (437), Expect = 2e-44
Identities = 101/279 (36%), Positives = 136/279 (48%), Gaps = 20/279 (7%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC-----DCFPGYEKDSKNHTCVDVNECEIVDGV 170
+++NEC + C G C N G +TC +C GY + + CVDV+EC
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 171 CGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC 229
CG G C N+ GSF C C+ GY D S++CVD++EC G +C NT GS+ C C
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSC 426
Query: 230 GHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS---HXXX 286
G L+ D SC+DI+ECS S CS C N G+YQC C GY S V
Sbjct: 427 SVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDID 483
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDECAGGARPCGGGQ-CR 344
C + C+N PGS+ C+C G+ L +G +C+DIDEC G C + C
Sbjct: 484 ECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGSNCQDIDECVTGIHNCSINETCF 543
Query: 345 NTVGSYTC---TCTDGLVPSAAG--AKPTCQDIDECADL 378
N G + C C + SAA + C + EC+ L
Sbjct: 544 NIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKL 582
Score = 153 bits (372), Expect = 1e-36
Identities = 101/283 (35%), Positives = 133/283 (46%), Gaps = 43/283 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCT 355
C+ C +T C+C G+ L +DG SC D++EC G+ C G+ C NTVGS+ C
Sbjct: 186 CKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRD 245
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
S+ G + + C D +DE + + +P+ C NT+GSF
Sbjct: 246 -----SSCGTGYELTEDNSCKD---------IDECESGIHNCLPDFI----CQNTLGSFR 287
Query: 416 C----QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR-----CRDGW 466
C QC G+ ++ G C D +EC + C CIN GS+ C+ C G+
Sbjct: 288 CRPKLQCKSGF-IQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 467 R--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+G C DVDEC C C N+ GSFRC C TGY DG CV
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRM-------CV 398
Query: 525 DIDECANDP-TLCENGH-CSNTPGGYECDCDVGFTRAADGRSC 565
D++EC P LC GH C NT G Y C C VGF + DGRSC
Sbjct: 399 DVNECQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 153 bits (371), Expect = 2e-36
Identities = 128/379 (33%), Positives = 173/379 (45%), Gaps = 61/379 (16%)
Query: 213 CRGG-----RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGT 266
CRGG +C +T C C G +L D +SC+D++EC S C G +C N +G+
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 239
Query: 267 YQCV----CDEGYAQSTVKSHXXXXXXXXXXXXRC--QHSCVNTPGSYHCT----CREGW 316
++C C GY + T + C C NT GS+ C C+ G+
Sbjct: 240 FRCQRDSSCGTGY-ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Query: 317 HLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
A G +C DI+EC + PC G C NT GSYTC VP+ ++ C
Sbjct: 299 IQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN---VPNCGRGYHLNEEGTRC 354
Query: 376 ADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTD 434
D VDE +P CG G C N+ GSF C+C GY C D
Sbjct: 355 VD---------VDECAPPAEP-----CGKGHRCVNSPGSFRCECKTGYYFDGISR-MCVD 399
Query: 435 DDECEL--GTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRA 490
+EC+ G H C N GS+ C C G+R DG +CED++EC ++ C
Sbjct: 400 VNECQRYPGRLCGHK---CENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQE- 453
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT---LCENGHCSNTPGG 547
CAN GS++C C GY+ L V V +C DIDECA PT +C C N PG
Sbjct: 454 -CANVYGSYQCYCRRGYQ-----LSDVDGV-TCEDIDECAL-PTGGHICSY-RCINIPGS 504
Query: 548 YECDC-DVGFTRAADGRSC 565
++C C G+ A +G +C
Sbjct: 505 FQCSCPSSGYRLAPNGSNC 523
Score = 130 bits (313), Expect = 2e-29
Identities = 87/248 (35%), Positives = 118/248 (47%), Gaps = 37/248 (14%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
D C GG PC QCR+T C+C G + G +C+D++EC
Sbjct: 178 DRCRGGG-PCKQ-QCRDTGDEVVCSCFVGYQLLSDGV--SCEDVNEC------------- 220
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCD 444
+ S ++ E SC NT+GSF CQ C GY + + +C D DECE G +
Sbjct: 221 -ITGSHSCRLGE-----SCINTVGSFRCQRDSSCGTGYELTEDN--SCKDIDECESGIHN 272
Query: 445 CHPAADCINLPGSFQCR----CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSF 499
C P C N GSF+CR C+ G+ D C D++ECL+ + C TC NT+GS+
Sbjct: 273 CLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSY 332
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTR 558
C + G GY L CVD+DECA C GH C N+PG + C+C G+
Sbjct: 333 TCQKNVPNCGRGYHLNEEGT--RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 559 AADGRSCL 566
R C+
Sbjct: 391 DGISRMCV 398
>AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein.
Length = 495
Score = 225 bits (549), Expect = 4e-58
Identities = 143/413 (34%), Positives = 190/413 (46%), Gaps = 60/413 (14%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCE----CG 230
C +T C C GY+ C D++EC CR G C+NT GSFRC+ CG
Sbjct: 60 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG 119
Query: 231 HGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQC----VCDEGYAQSTVKSHXX 285
G EL D SCKDIDEC C + C+N +G+++C C G+ Q + +
Sbjct: 120 TGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL-GNCI 177
Query: 286 XXXXXXXXXXRCQ--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPC 338
C H+C+NT GSY C C G+HL +G C D+DECA A PC
Sbjct: 178 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 237
Query: 339 GGG-QCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
G G +C N+ GS+ C C G G C D++EC
Sbjct: 238 GKGHRCVNSPGSFRCECKTGYYFD--GISRMCVDVNECQRYPG----------------- 278
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
LCG C NT+GS++C C G+ + + G +C D +EC C + +C N+ GS
Sbjct: 279 --RLCGH-KCENTLGSYLCSCSVGFRLSVD-GRSCEDINECSSSPC----SQECANVYGS 330
Query: 458 FQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+QC CR G++ DG TCED+DEC GG C N GSF+C C + G
Sbjct: 331 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS------GY 384
Query: 515 RTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYEC---DCDVGFTRAADGR 563
R +C DIDEC C N C N GG+ C +C + R+A R
Sbjct: 385 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATR 437
Score = 213 bits (521), Expect = 1e-54
Identities = 151/435 (34%), Positives = 191/435 (43%), Gaps = 56/435 (12%)
Query: 133 RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----C 187
+CR+ C CF GY+ S +C DVNEC C G+ C NT GSF C C
Sbjct: 59 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 118
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC----ECGHGMELAPDRL-S 241
GY+ + C DIDEC C C NT GSFRC +C G D L +
Sbjct: 119 GTGYELTE-DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG--FIQDALGN 175
Query: 242 CKDIDECSITSGICSNG-ACENQMGTYQCV-----CDEGYAQSTVKSHXXXXXXXXXXXX 295
C DI+EC S C G C N G+Y C C GY + +
Sbjct: 176 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 235
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H CVN+PGS+ C C+ G++ R C D++EC G +C NT+GSY C+
Sbjct: 236 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 295
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C+ G S G +C+DI+EC S P C + C N GS
Sbjct: 296 CSVGFRLSVDGR--SCEDINEC-----------------SSSP-----C-SQECANVYGS 330
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDGWR--GDG 470
+ C C GY + G C D DEC L T + CIN+PGSFQC C G+R +G
Sbjct: 331 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG 390
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLRTVCCVYSCVDID 527
C+D+DEC+T C TC N G FRCL C Y+ T C C +
Sbjct: 391 RNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA---ATRCERLPCHENR 447
Query: 528 ECANDPTLCENGHCS 542
EC+ P H S
Sbjct: 448 ECSKLPLRITYYHLS 462
Score = 182 bits (443), Expect = 3e-45
Identities = 102/279 (36%), Positives = 137/279 (49%), Gaps = 20/279 (7%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC-----DCFPGYEKDSKNHTCVDVNECEIVDGV 170
+++NEC + C G C N G +TC +C GY + + CVDV+EC
Sbjct: 177 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 236
Query: 171 CGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC 229
CG G C N+ GSF C C+ GY D S++CVD++EC G +C NT GS+ C C
Sbjct: 237 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSC 296
Query: 230 GHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS---HXXX 286
G L+ D SC+DI+ECS S CS C N G+YQC C GY S V
Sbjct: 297 SVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDID 353
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDECAGGARPCGGGQ-CR 344
C + C+N PGS+ C+C G+ L +GR+C+DIDEC G C + C
Sbjct: 354 ECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF 413
Query: 345 NTVGSYTC---TCTDGLVPSAAG--AKPTCQDIDECADL 378
N G + C C + SAA + C + EC+ L
Sbjct: 414 NIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKL 452
Score = 155 bits (377), Expect = 3e-37
Identities = 129/379 (34%), Positives = 175/379 (46%), Gaps = 61/379 (16%)
Query: 213 CRGG-----RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGT 266
CRGG +C +T C C G +L D +SC+D++EC S C G +C N +G+
Sbjct: 50 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 109
Query: 267 YQC----VCDEGYAQSTVKSHXXXXXXXXXXXXRC--QHSCVNTPGSYHC----TCREGW 316
++C C GY + T + C C NT GS+ C C+ G+
Sbjct: 110 FRCQRDSSCGTGY-ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 168
Query: 317 HLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
A G +C DI+EC + PC G C NT GSYTC VP+ ++ C
Sbjct: 169 IQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN---VPNCGRGYHLNEEGTRC 224
Query: 376 ADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTIGSFVCQCPDGYSVKPEQGPACTD 434
D VDE +P CG G C N+ GSF C+C GY C D
Sbjct: 225 VD---------VDECAPPAEP-----CGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVD 269
Query: 435 DDECEL--GTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRA 490
+EC+ G H C N GS+ C C G+R DG +CED++EC ++ C
Sbjct: 270 VNECQRYPGRLCGH---KCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQE- 323
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT---LCENGHCSNTPGG 547
CAN GS++C C GY+ L V V +C DIDECA PT +C + C N PG
Sbjct: 324 -CANVYGSYQCYCRRGYQ-----LSDVDGV-TCEDIDECAL-PTGGHIC-SYRCINIPGS 374
Query: 548 YECDC-DVGFTRAADGRSC 565
++C C G+ A +GR+C
Sbjct: 375 FQCSCPSSGYRLAPNGRNC 393
Score = 130 bits (313), Expect = 2e-29
Identities = 87/248 (35%), Positives = 118/248 (47%), Gaps = 37/248 (14%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
D C GG PC QCR+T C+C G + G +C+D++EC
Sbjct: 48 DRCRGGG-PCKQ-QCRDTGDEVVCSCFVGYQLLSDGV--SCEDVNEC------------- 90
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCD 444
+ S ++ E SC NT+GSF CQ C GY + + +C D DECE G +
Sbjct: 91 -ITGSHSCRLGE-----SCINTVGSFRCQRDSSCGTGYELTEDN--SCKDIDECESGIHN 142
Query: 445 CHPAADCINLPGSFQCR----CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSF 499
C P C N GSF+CR C+ G+ D C D++ECL+ + C TC NT+GS+
Sbjct: 143 CLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSY 202
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTR 558
C + G GY L CVD+DECA C GH C N+PG + C+C G+
Sbjct: 203 TCQKNVPNCGRGYHLNEEGT--RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 260
Query: 559 AADGRSCL 566
R C+
Sbjct: 261 DGISRMCV 268
>Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 224 bits (548), Expect = 6e-58
Identities = 142/410 (34%), Positives = 189/410 (46%), Gaps = 60/410 (14%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCE----CG 230
C +T C C GY+ C D++EC CR G C+NT GSFRC+ CG
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG 249
Query: 231 HGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQC----VCDEGYAQSTVKSHXX 285
G EL D SCKDIDEC C + C+N +G+++C C G+ Q + +
Sbjct: 250 TGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL-GNCI 307
Query: 286 XXXXXXXXXXRCQ--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPC 338
C H+C+NT GSY C C G+HL +G C D+DECA A PC
Sbjct: 308 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Query: 339 GGG-QCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
G G +C N+ GS+ C C G G C D++EC
Sbjct: 368 GKGHRCVNSPGSFRCECKTGYYFD--GISRMCVDVNECQRYPG----------------- 408
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
LCG C NT+GS++C C G+ + + G +C D +EC C + +C N+ GS
Sbjct: 409 --RLCGH-KCENTLGSYLCSCSVGFRLSVD-GRSCEDINECSSSPC----SQECANVYGS 460
Query: 458 FQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+QC CR G++ DG TCED+DEC GG C N GSF+C C + G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS------GY 514
Query: 515 RTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYEC---DCDVGFTRAA 560
R +C DIDEC C N C N GG+ C +C + R+A
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 564
Score = 217 bits (530), Expect = 9e-56
Identities = 153/432 (35%), Positives = 193/432 (44%), Gaps = 59/432 (13%)
Query: 133 RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----C 187
+CR+ C CF GY+ S +C DVNEC C G+ C NT GSF C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC----ECGHGMELAPDRL-S 241
GY+ + C DIDEC C C NT GSFRC +C G D L +
Sbjct: 249 GTGYELTE-DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG--FIQDALGN 305
Query: 242 CKDIDECSITSGICSNG-ACENQMGTYQCV-----CDEGYAQSTVKSHXXXXXXXXXXXX 295
C DI+EC S C G C N G+Y C C GY + +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H CVN+PGS+ C C+ G++ R C D++EC G +C NT+GSY C+
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C+ G S G +C+DI+EC S P C + C N GS
Sbjct: 426 CSVGFRLSVDGR--SCEDINEC-----------------SSSP-----C-SQECANVYGS 460
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDGWR--GDG 470
+ C C GY + G C D DEC L T + CIN+PGSFQC C G+R +G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG 520
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLR-----TVCCVYS 522
C+D+DEC+T C TC N G FRCL C Y+ L+ TV C+ S
Sbjct: 521 RNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKS 580
Query: 523 CVDID-ECANDP 533
C D C DP
Sbjct: 581 CRPNDVTCVFDP 592
Score = 206 bits (502), Expect = 2e-52
Identities = 141/402 (35%), Positives = 179/402 (44%), Gaps = 56/402 (13%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCD----CFPGYEKDSKNHTCVDVNECEI-VDGVC 171
+VNEC C G C N +G F C C GYE N +C D++ECE +
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCL 274
Query: 172 GDGDCHNTEGSFTCH----CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR 226
D C NT GSF C C+ G+ D C+DI+EC A C G C+NT GS+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 227 CE-----CGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTV 280
C+ CG G L + C D+DEC+ + C G C N G+++C C GY +
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 281 KSHXXXXXXXXXXXXR-CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
R C H C NT GSY C+C G+ L DGRSC DI+EC+ PC
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSS--PCS 451
Query: 340 GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIP 399
+C N GSY C C G S TC+DIDECA P
Sbjct: 452 Q-ECANVYGSYQCYCRRGYQLSDVDGV-TCEDIDECA------------------LPTGG 491
Query: 400 ELCGAGSCHNTIGSFVCQCP-DGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
+C + C N GSF C CP GY + P G C D DEC G +C C N+ G F
Sbjct: 492 HIC-SYRCINIPGSFQCSCPSSGYRLAP-NGRNCQDIDECVTGIHNCSINETCFNIQGGF 549
Query: 459 QC---RCRDGWRGDGATCE----DVDECLTNNGGCHPR-ATC 492
+C C + +R AT + D C+ + C P TC
Sbjct: 550 RCLAFECPENYRRSAATLQQEKTDTVRCIKS---CRPNDVTC 588
Score = 181 bits (440), Expect = 7e-45
Identities = 100/274 (36%), Positives = 133/274 (48%), Gaps = 18/274 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC-----DCFPGYEKDSKNHTCVDVNECEIVDGV 170
+++NEC + C G C N G +TC +C GY + + CVDV+EC
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 171 CGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC 229
CG G C N+ GSF C C+ GY D S++CVD++EC G +C NT GS+ C C
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSC 426
Query: 230 GHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS---HXXX 286
G L+ D SC+DI+ECS S CS C N G+YQC C GY S V
Sbjct: 427 SVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDID 483
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDECAGGARPCGGGQ-CR 344
C + C+N PGS+ C+C G+ L +GR+C+DIDEC G C + C
Sbjct: 484 ECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF 543
Query: 345 NTVGSYTC---TCTDGLVPSAAGAKPTCQDIDEC 375
N G + C C + SAA + D C
Sbjct: 544 NIQGGFRCLAFECPENYRRSAATLQQEKTDTVRC 577
Score = 155 bits (377), Expect = 3e-37
Identities = 129/379 (34%), Positives = 175/379 (46%), Gaps = 61/379 (16%)
Query: 213 CRGG-----RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGT 266
CRGG +C +T C C G +L D +SC+D++EC S C G +C N +G+
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 239
Query: 267 YQC----VCDEGYAQSTVKSHXXXXXXXXXXXXRC--QHSCVNTPGSYHC----TCREGW 316
++C C GY + T + C C NT GS+ C C+ G+
Sbjct: 240 FRCQRDSSCGTGY-ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Query: 317 HLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
A G +C DI+EC + PC G C NT GSYTC VP+ ++ C
Sbjct: 299 IQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN---VPNCGRGYHLNEEGTRC 354
Query: 376 ADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTIGSFVCQCPDGYSVKPEQGPACTD 434
D VDE +P CG G C N+ GSF C+C GY C D
Sbjct: 355 VD---------VDECAPPAEP-----CGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVD 399
Query: 435 DDECEL--GTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRA 490
+EC+ G H C N GS+ C C G+R DG +CED++EC ++ C
Sbjct: 400 VNECQRYPGRLCGH---KCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQE- 453
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT---LCENGHCSNTPGG 547
CAN GS++C C GY+ L V V +C DIDECA PT +C + C N PG
Sbjct: 454 -CANVYGSYQCYCRRGYQ-----LSDVDGV-TCEDIDECAL-PTGGHIC-SYRCINIPGS 504
Query: 548 YECDC-DVGFTRAADGRSC 565
++C C G+ A +GR+C
Sbjct: 505 FQCSCPSSGYRLAPNGRNC 523
Score = 130 bits (313), Expect = 2e-29
Identities = 87/248 (35%), Positives = 118/248 (47%), Gaps = 37/248 (14%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
D C GG PC QCR+T C+C G + G +C+D++EC
Sbjct: 178 DRCRGGG-PCKQ-QCRDTGDEVVCSCFVGYQLLSDGV--SCEDVNEC------------- 220
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCD 444
+ S ++ E SC NT+GSF CQ C GY + + +C D DECE G +
Sbjct: 221 -ITGSHSCRLGE-----SCINTVGSFRCQRDSSCGTGYELTEDN--SCKDIDECESGIHN 272
Query: 445 CHPAADCINLPGSFQCR----CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSF 499
C P C N GSF+CR C+ G+ D C D++ECL+ + C TC NT+GS+
Sbjct: 273 CLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSY 332
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTR 558
C + G GY L CVD+DECA C GH C N+PG + C+C G+
Sbjct: 333 TCQKNVPNCGRGYHLNEEGT--RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 559 AADGRSCL 566
R C+
Sbjct: 391 DGISRMCV 398
>Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 224 bits (548), Expect = 6e-58
Identities = 142/410 (34%), Positives = 189/410 (46%), Gaps = 60/410 (14%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCE----CG 230
C +T C C GY+ C D++EC CR G C+NT GSFRC+ CG
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG 249
Query: 231 HGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQC----VCDEGYAQSTVKSHXX 285
G EL D SCKDIDEC C + C+N +G+++C C G+ Q + +
Sbjct: 250 TGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL-GNCI 307
Query: 286 XXXXXXXXXXRCQ--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPC 338
C H+C+NT GSY C C G+HL +G C D+DECA A PC
Sbjct: 308 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Query: 339 GGG-QCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
G G +C N+ GS+ C C G G C D++EC
Sbjct: 368 GKGHRCVNSPGSFRCECKTGYYFD--GISRMCVDVNECQRYPG----------------- 408
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
LCG C NT+GS++C C G+ + + G +C D +EC C + +C N+ GS
Sbjct: 409 --RLCGH-KCENTLGSYLCSCSVGFRLSVD-GRSCEDINECSSSPC----SQECANVYGS 460
Query: 458 FQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+QC CR G++ DG TCED+DEC GG C N GSF+C C + G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS------GY 514
Query: 515 RTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYEC---DCDVGFTRAA 560
R +C DIDEC C N C N GG+ C +C + R+A
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 564
Score = 217 bits (530), Expect = 9e-56
Identities = 153/432 (35%), Positives = 193/432 (44%), Gaps = 59/432 (13%)
Query: 133 RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----C 187
+CR+ C CF GY+ S +C DVNEC C G+ C NT GSF C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC----ECGHGMELAPDRL-S 241
GY+ + C DIDEC C C NT GSFRC +C G D L +
Sbjct: 249 GTGYELTE-DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG--FIQDALGN 305
Query: 242 CKDIDECSITSGICSNG-ACENQMGTYQCV-----CDEGYAQSTVKSHXXXXXXXXXXXX 295
C DI+EC S C G C N G+Y C C GY + +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H CVN+PGS+ C C+ G++ R C D++EC G +C NT+GSY C+
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C+ G S G +C+DI+EC S P C + C N GS
Sbjct: 426 CSVGFRLSVDGR--SCEDINEC-----------------SSSP-----C-SQECANVYGS 460
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDGWR--GDG 470
+ C C GY + G C D DEC L T + CIN+PGSFQC C G+R +G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG 520
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLR-----TVCCVYS 522
C+D+DEC+T C TC N G FRCL C Y+ L+ TV C+ S
Sbjct: 521 RNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKS 580
Query: 523 CVDID-ECANDP 533
C D C DP
Sbjct: 581 CRPNDVTCVFDP 592
Score = 206 bits (502), Expect = 2e-52
Identities = 141/402 (35%), Positives = 179/402 (44%), Gaps = 56/402 (13%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCD----CFPGYEKDSKNHTCVDVNECEI-VDGVC 171
+VNEC C G C N +G F C C GYE N +C D++ECE +
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCL 274
Query: 172 GDGDCHNTEGSFTCH----CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR 226
D C NT GSF C C+ G+ D C+DI+EC A C G C+NT GS+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 227 CE-----CGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTV 280
C+ CG G L + C D+DEC+ + C G C N G+++C C GY +
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 281 KSHXXXXXXXXXXXXR-CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
R C H C NT GSY C+C G+ L DGRSC DI+EC+ PC
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSS--PCS 451
Query: 340 GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIP 399
+C N GSY C C G S TC+DIDECA P
Sbjct: 452 Q-ECANVYGSYQCYCRRGYQLSDVDGV-TCEDIDECA------------------LPTGG 491
Query: 400 ELCGAGSCHNTIGSFVCQCP-DGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
+C + C N GSF C CP GY + P G C D DEC G +C C N+ G F
Sbjct: 492 HIC-SYRCINIPGSFQCSCPSSGYRLAP-NGRNCQDIDECVTGIHNCSINETCFNIQGGF 549
Query: 459 QC---RCRDGWRGDGATCE----DVDECLTNNGGCHPR-ATC 492
+C C + +R AT + D C+ + C P TC
Sbjct: 550 RCLAFECPENYRRSAATLQQEKTDTVRCIKS---CRPNDVTC 588
Score = 181 bits (440), Expect = 7e-45
Identities = 100/274 (36%), Positives = 133/274 (48%), Gaps = 18/274 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC-----DCFPGYEKDSKNHTCVDVNECEIVDGV 170
+++NEC + C G C N G +TC +C GY + + CVDV+EC
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 171 CGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC 229
CG G C N+ GSF C C+ GY D S++CVD++EC G +C NT GS+ C C
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSC 426
Query: 230 GHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS---HXXX 286
G L+ D SC+DI+ECS S CS C N G+YQC C GY S V
Sbjct: 427 SVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDID 483
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDECAGGARPCGGGQ-CR 344
C + C+N PGS+ C+C G+ L +GR+C+DIDEC G C + C
Sbjct: 484 ECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF 543
Query: 345 NTVGSYTC---TCTDGLVPSAAGAKPTCQDIDEC 375
N G + C C + SAA + D C
Sbjct: 544 NIQGGFRCLAFECPENYRRSAATLQQEKTDTVRC 577
Score = 155 bits (377), Expect = 3e-37
Identities = 129/379 (34%), Positives = 175/379 (46%), Gaps = 61/379 (16%)
Query: 213 CRGG-----RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGT 266
CRGG +C +T C C G +L D +SC+D++EC S C G +C N +G+
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 239
Query: 267 YQC----VCDEGYAQSTVKSHXXXXXXXXXXXXRC--QHSCVNTPGSYHC----TCREGW 316
++C C GY + T + C C NT GS+ C C+ G+
Sbjct: 240 FRCQRDSSCGTGY-ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Query: 317 HLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
A G +C DI+EC + PC G C NT GSYTC VP+ ++ C
Sbjct: 299 IQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN---VPNCGRGYHLNEEGTRC 354
Query: 376 ADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTIGSFVCQCPDGYSVKPEQGPACTD 434
D VDE +P CG G C N+ GSF C+C GY C D
Sbjct: 355 VD---------VDECAPPAEP-----CGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVD 399
Query: 435 DDECEL--GTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRA 490
+EC+ G H C N GS+ C C G+R DG +CED++EC ++ C
Sbjct: 400 VNECQRYPGRLCGH---KCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQE- 453
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT---LCENGHCSNTPGG 547
CAN GS++C C GY+ L V V +C DIDECA PT +C + C N PG
Sbjct: 454 -CANVYGSYQCYCRRGYQ-----LSDVDGV-TCEDIDECAL-PTGGHIC-SYRCINIPGS 504
Query: 548 YECDC-DVGFTRAADGRSC 565
++C C G+ A +GR+C
Sbjct: 505 FQCSCPSSGYRLAPNGRNC 523
Score = 130 bits (313), Expect = 2e-29
Identities = 87/248 (35%), Positives = 118/248 (47%), Gaps = 37/248 (14%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
D C GG PC QCR+T C+C G + G +C+D++EC
Sbjct: 178 DRCRGGG-PCKQ-QCRDTGDEVVCSCFVGYQLLSDGV--SCEDVNEC------------- 220
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCD 444
+ S ++ E SC NT+GSF CQ C GY + + +C D DECE G +
Sbjct: 221 -ITGSHSCRLGE-----SCINTVGSFRCQRDSSCGTGYELTEDN--SCKDIDECESGIHN 272
Query: 445 CHPAADCINLPGSFQCR----CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSF 499
C P C N GSF+CR C+ G+ D C D++ECL+ + C TC NT+GS+
Sbjct: 273 CLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSY 332
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTR 558
C + G GY L CVD+DECA C GH C N+PG + C+C G+
Sbjct: 333 TCQKNVPNCGRGYHLNEEGT--RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 559 AADGRSCL 566
R C+
Sbjct: 391 DGISRMCV 398
>AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 224 bits (548), Expect = 6e-58
Identities = 142/410 (34%), Positives = 189/410 (46%), Gaps = 60/410 (14%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCE----CG 230
C +T C C GY+ C D++EC CR G C+NT GSFRC+ CG
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG 249
Query: 231 HGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQC----VCDEGYAQSTVKSHXX 285
G EL D SCKDIDEC C + C+N +G+++C C G+ Q + +
Sbjct: 250 TGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL-GNCI 307
Query: 286 XXXXXXXXXXRCQ--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPC 338
C H+C+NT GSY C C G+HL +G C D+DECA A PC
Sbjct: 308 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Query: 339 GGG-QCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
G G +C N+ GS+ C C G G C D++EC
Sbjct: 368 GKGHRCVNSPGSFRCECKTGYYFD--GISRMCVDVNECQRYPG----------------- 408
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
LCG C NT+GS++C C G+ + + G +C D +EC C + +C N+ GS
Sbjct: 409 --RLCGH-KCENTLGSYLCSCSVGFRLSVD-GRSCEDINECSSSPC----SQECANVYGS 460
Query: 458 FQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+QC CR G++ DG TCED+DEC GG C N GSF+C C + G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS------GY 514
Query: 515 RTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYEC---DCDVGFTRAA 560
R +C DIDEC C N C N GG+ C +C + R+A
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 564
Score = 217 bits (530), Expect = 9e-56
Identities = 153/432 (35%), Positives = 193/432 (44%), Gaps = 59/432 (13%)
Query: 133 RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----C 187
+CR+ C CF GY+ S +C DVNEC C G+ C NT GSF C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC----ECGHGMELAPDRL-S 241
GY+ + C DIDEC C C NT GSFRC +C G D L +
Sbjct: 249 GTGYELTE-DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG--FIQDALGN 305
Query: 242 CKDIDECSITSGICSNG-ACENQMGTYQCV-----CDEGYAQSTVKSHXXXXXXXXXXXX 295
C DI+EC S C G C N G+Y C C GY + +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H CVN+PGS+ C C+ G++ R C D++EC G +C NT+GSY C+
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C+ G S G +C+DI+EC S P C + C N GS
Sbjct: 426 CSVGFRLSVDGR--SCEDINEC-----------------SSSP-----C-SQECANVYGS 460
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDGWR--GDG 470
+ C C GY + G C D DEC L T + CIN+PGSFQC C G+R +G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG 520
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLR-----TVCCVYS 522
C+D+DEC+T C TC N G FRCL C Y+ L+ TV C+ S
Sbjct: 521 RNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKS 580
Query: 523 CVDID-ECANDP 533
C D C DP
Sbjct: 581 CRPNDVTCVFDP 592
Score = 206 bits (502), Expect = 2e-52
Identities = 141/402 (35%), Positives = 179/402 (44%), Gaps = 56/402 (13%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCD----CFPGYEKDSKNHTCVDVNECEI-VDGVC 171
+VNEC C G C N +G F C C GYE N +C D++ECE +
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCL 274
Query: 172 GDGDCHNTEGSFTCH----CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR 226
D C NT GSF C C+ G+ D C+DI+EC A C G C+NT GS+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 227 CE-----CGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTV 280
C+ CG G L + C D+DEC+ + C G C N G+++C C GY +
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 281 KSHXXXXXXXXXXXXR-CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
R C H C NT GSY C+C G+ L DGRSC DI+EC+ PC
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSS--PCS 451
Query: 340 GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIP 399
+C N GSY C C G S TC+DIDECA P
Sbjct: 452 Q-ECANVYGSYQCYCRRGYQLSDVDGV-TCEDIDECA------------------LPTGG 491
Query: 400 ELCGAGSCHNTIGSFVCQCP-DGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
+C + C N GSF C CP GY + P G C D DEC G +C C N+ G F
Sbjct: 492 HIC-SYRCINIPGSFQCSCPSSGYRLAP-NGRNCQDIDECVTGIHNCSINETCFNIQGGF 549
Query: 459 QC---RCRDGWRGDGATCE----DVDECLTNNGGCHPR-ATC 492
+C C + +R AT + D C+ + C P TC
Sbjct: 550 RCLAFECPENYRRSAATLQQEKTDTVRCIKS---CRPNDVTC 588
Score = 181 bits (440), Expect = 7e-45
Identities = 100/274 (36%), Positives = 133/274 (48%), Gaps = 18/274 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC-----DCFPGYEKDSKNHTCVDVNECEIVDGV 170
+++NEC + C G C N G +TC +C GY + + CVDV+EC
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 171 CGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC 229
CG G C N+ GSF C C+ GY D S++CVD++EC G +C NT GS+ C C
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSC 426
Query: 230 GHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS---HXXX 286
G L+ D SC+DI+ECS S CS C N G+YQC C GY S V
Sbjct: 427 SVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDID 483
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDECAGGARPCGGGQ-CR 344
C + C+N PGS+ C+C G+ L +GR+C+DIDEC G C + C
Sbjct: 484 ECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF 543
Query: 345 NTVGSYTC---TCTDGLVPSAAGAKPTCQDIDEC 375
N G + C C + SAA + D C
Sbjct: 544 NIQGGFRCLAFECPENYRRSAATLQQEKTDTVRC 577
Score = 155 bits (377), Expect = 3e-37
Identities = 129/379 (34%), Positives = 175/379 (46%), Gaps = 61/379 (16%)
Query: 213 CRGG-----RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGT 266
CRGG +C +T C C G +L D +SC+D++EC S C G +C N +G+
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 239
Query: 267 YQC----VCDEGYAQSTVKSHXXXXXXXXXXXXRC--QHSCVNTPGSYHC----TCREGW 316
++C C GY + T + C C NT GS+ C C+ G+
Sbjct: 240 FRCQRDSSCGTGY-ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Query: 317 HLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
A G +C DI+EC + PC G C NT GSYTC VP+ ++ C
Sbjct: 299 IQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN---VPNCGRGYHLNEEGTRC 354
Query: 376 ADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTIGSFVCQCPDGYSVKPEQGPACTD 434
D VDE +P CG G C N+ GSF C+C GY C D
Sbjct: 355 VD---------VDECAPPAEP-----CGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVD 399
Query: 435 DDECEL--GTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRA 490
+EC+ G H C N GS+ C C G+R DG +CED++EC ++ C
Sbjct: 400 VNECQRYPGRLCGH---KCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQE- 453
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT---LCENGHCSNTPGG 547
CAN GS++C C GY+ L V V +C DIDECA PT +C + C N PG
Sbjct: 454 -CANVYGSYQCYCRRGYQ-----LSDVDGV-TCEDIDECAL-PTGGHIC-SYRCINIPGS 504
Query: 548 YECDC-DVGFTRAADGRSC 565
++C C G+ A +GR+C
Sbjct: 505 FQCSCPSSGYRLAPNGRNC 523
Score = 130 bits (313), Expect = 2e-29
Identities = 87/248 (35%), Positives = 118/248 (47%), Gaps = 37/248 (14%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
D C GG PC QCR+T C+C G + G +C+D++EC
Sbjct: 178 DRCRGGG-PCKQ-QCRDTGDEVVCSCFVGYQLLSDGV--SCEDVNEC------------- 220
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCD 444
+ S ++ E SC NT+GSF CQ C GY + + +C D DECE G +
Sbjct: 221 -ITGSHSCRLGE-----SCINTVGSFRCQRDSSCGTGYELTEDN--SCKDIDECESGIHN 272
Query: 445 CHPAADCINLPGSFQCR----CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSF 499
C P C N GSF+CR C+ G+ D C D++ECL+ + C TC NT+GS+
Sbjct: 273 CLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSY 332
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTR 558
C + G GY L CVD+DECA C GH C N+PG + C+C G+
Sbjct: 333 TCQKNVPNCGRGYHLNEEGT--RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 559 AADGRSCL 566
R C+
Sbjct: 391 DGISRMCV 398
>AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens
cDNA PSEC0266 fis, clone NT2RP3003649, highly similar to
Homo sapiens fibulin-1D mRNA. ).
Length = 638
Score = 224 bits (548), Expect = 6e-58
Identities = 142/410 (34%), Positives = 189/410 (46%), Gaps = 60/410 (14%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCE----CG 230
C +T C C GY+ C D++EC CR G C+NT GSFRC+ CG
Sbjct: 125 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG 184
Query: 231 HGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQC----VCDEGYAQSTVKSHXX 285
G EL D SCKDIDEC C + C+N +G+++C C G+ Q + +
Sbjct: 185 TGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL-GNCI 242
Query: 286 XXXXXXXXXXRCQ--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPC 338
C H+C+NT GSY C C G+HL +G C D+DECA A PC
Sbjct: 243 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 302
Query: 339 GGG-QCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
G G +C N+ GS+ C C G G C D++EC
Sbjct: 303 GKGHRCVNSPGSFRCECKTGYYFD--GISRMCVDVNECQRYPG----------------- 343
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
LCG C NT+GS++C C G+ + + G +C D +EC C + +C N+ GS
Sbjct: 344 --RLCGH-KCENTLGSYLCSCSVGFRLSVD-GRSCEDINECSSSPC----SQECANVYGS 395
Query: 458 FQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+QC CR G++ DG TCED+DEC GG C N GSF+C C + G
Sbjct: 396 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS------GY 449
Query: 515 RTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYEC---DCDVGFTRAA 560
R +C DIDEC C N C N GG+ C +C + R+A
Sbjct: 450 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 499
Score = 217 bits (530), Expect = 9e-56
Identities = 153/432 (35%), Positives = 193/432 (44%), Gaps = 59/432 (13%)
Query: 133 RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----C 187
+CR+ C CF GY+ S +C DVNEC C G+ C NT GSF C C
Sbjct: 124 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 183
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC----ECGHGMELAPDRL-S 241
GY+ + C DIDEC C C NT GSFRC +C G D L +
Sbjct: 184 GTGYELTE-DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG--FIQDALGN 240
Query: 242 CKDIDECSITSGICSNG-ACENQMGTYQCV-----CDEGYAQSTVKSHXXXXXXXXXXXX 295
C DI+EC S C G C N G+Y C C GY + +
Sbjct: 241 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 300
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H CVN+PGS+ C C+ G++ R C D++EC G +C NT+GSY C+
Sbjct: 301 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 360
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C+ G S G +C+DI+EC S P C + C N GS
Sbjct: 361 CSVGFRLSVDGR--SCEDINEC-----------------SSSP-----C-SQECANVYGS 395
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDGWR--GDG 470
+ C C GY + G C D DEC L T + CIN+PGSFQC C G+R +G
Sbjct: 396 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG 455
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLR-----TVCCVYS 522
C+D+DEC+T C TC N G FRCL C Y+ L+ TV C+ S
Sbjct: 456 RNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKS 515
Query: 523 CVDID-ECANDP 533
C D C DP
Sbjct: 516 CRPNDVTCVFDP 527
Score = 206 bits (502), Expect = 2e-52
Identities = 141/402 (35%), Positives = 179/402 (44%), Gaps = 56/402 (13%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCD----CFPGYEKDSKNHTCVDVNECEI-VDGVC 171
+VNEC C G C N +G F C C GYE N +C D++ECE +
Sbjct: 151 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCL 209
Query: 172 GDGDCHNTEGSFTCH----CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR 226
D C NT GSF C C+ G+ D C+DI+EC A C G C+NT GS+
Sbjct: 210 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT 268
Query: 227 CE-----CGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTV 280
C+ CG G L + C D+DEC+ + C G C N G+++C C GY +
Sbjct: 269 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 328
Query: 281 KSHXXXXXXXXXXXXR-CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
R C H C NT GSY C+C G+ L DGRSC DI+EC+ PC
Sbjct: 329 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSS--PCS 386
Query: 340 GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIP 399
+C N GSY C C G S TC+DIDECA P
Sbjct: 387 Q-ECANVYGSYQCYCRRGYQLSDVDGV-TCEDIDECA------------------LPTGG 426
Query: 400 ELCGAGSCHNTIGSFVCQCP-DGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
+C + C N GSF C CP GY + P G C D DEC G +C C N+ G F
Sbjct: 427 HIC-SYRCINIPGSFQCSCPSSGYRLAP-NGRNCQDIDECVTGIHNCSINETCFNIQGGF 484
Query: 459 QC---RCRDGWRGDGATCE----DVDECLTNNGGCHPR-ATC 492
+C C + +R AT + D C+ + C P TC
Sbjct: 485 RCLAFECPENYRRSAATLQQEKTDTVRCIKS---CRPNDVTC 523
Score = 181 bits (440), Expect = 7e-45
Identities = 100/274 (36%), Positives = 133/274 (48%), Gaps = 18/274 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC-----DCFPGYEKDSKNHTCVDVNECEIVDGV 170
+++NEC + C G C N G +TC +C GY + + CVDV+EC
Sbjct: 242 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 301
Query: 171 CGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC 229
CG G C N+ GSF C C+ GY D S++CVD++EC G +C NT GS+ C C
Sbjct: 302 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSC 361
Query: 230 GHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS---HXXX 286
G L+ D SC+DI+ECS S CS C N G+YQC C GY S V
Sbjct: 362 SVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDID 418
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDECAGGARPCGGGQ-CR 344
C + C+N PGS+ C+C G+ L +GR+C+DIDEC G C + C
Sbjct: 419 ECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF 478
Query: 345 NTVGSYTC---TCTDGLVPSAAGAKPTCQDIDEC 375
N G + C C + SAA + D C
Sbjct: 479 NIQGGFRCLAFECPENYRRSAATLQQEKTDTVRC 512
Score = 155 bits (377), Expect = 3e-37
Identities = 129/379 (34%), Positives = 175/379 (46%), Gaps = 61/379 (16%)
Query: 213 CRGG-----RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGT 266
CRGG +C +T C C G +L D +SC+D++EC S C G +C N +G+
Sbjct: 115 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 174
Query: 267 YQC----VCDEGYAQSTVKSHXXXXXXXXXXXXRC--QHSCVNTPGSYHC----TCREGW 316
++C C GY + T + C C NT GS+ C C+ G+
Sbjct: 175 FRCQRDSSCGTGY-ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 233
Query: 317 HLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
A G +C DI+EC + PC G C NT GSYTC VP+ ++ C
Sbjct: 234 IQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN---VPNCGRGYHLNEEGTRC 289
Query: 376 ADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTIGSFVCQCPDGYSVKPEQGPACTD 434
D VDE +P CG G C N+ GSF C+C GY C D
Sbjct: 290 VD---------VDECAPPAEP-----CGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVD 334
Query: 435 DDECEL--GTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRA 490
+EC+ G H C N GS+ C C G+R DG +CED++EC ++ C
Sbjct: 335 VNECQRYPGRLCGH---KCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQE- 388
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT---LCENGHCSNTPGG 547
CAN GS++C C GY+ L V V +C DIDECA PT +C + C N PG
Sbjct: 389 -CANVYGSYQCYCRRGYQ-----LSDVDGV-TCEDIDECAL-PTGGHIC-SYRCINIPGS 439
Query: 548 YECDC-DVGFTRAADGRSC 565
++C C G+ A +GR+C
Sbjct: 440 FQCSCPSSGYRLAPNGRNC 458
Score = 130 bits (313), Expect = 2e-29
Identities = 87/248 (35%), Positives = 118/248 (47%), Gaps = 37/248 (14%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
D C GG PC QCR+T C+C G + G +C+D++EC
Sbjct: 113 DRCRGGG-PCKQ-QCRDTGDEVVCSCFVGYQLLSDGV--SCEDVNEC------------- 155
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCD 444
+ S ++ E SC NT+GSF CQ C GY + + +C D DECE G +
Sbjct: 156 -ITGSHSCRLGE-----SCINTVGSFRCQRDSSCGTGYELTEDN--SCKDIDECESGIHN 207
Query: 445 CHPAADCINLPGSFQCR----CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSF 499
C P C N GSF+CR C+ G+ D C D++ECL+ + C TC NT+GS+
Sbjct: 208 CLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSY 267
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTR 558
C + G GY L CVD+DECA C GH C N+PG + C+C G+
Sbjct: 268 TCQKNVPNCGRGYHLNEEGT--RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 325
Query: 559 AADGRSCL 566
R C+
Sbjct: 326 DGISRMCV 333
>AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 223 bits (544), Expect = 2e-57
Identities = 156/430 (36%), Positives = 198/430 (46%), Gaps = 65/430 (15%)
Query: 134 CRNLLGGFTCD-----CFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH- 186
C N LG F C C GY ++ + CVD+NEC C G+ C NT GSF C+
Sbjct: 736 CVNTLGSFYCVNHTVLCADGYILNA-HRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYK 794
Query: 187 ---CRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRCE----CGHGMELAPD 238
C PGY D C D+DECA C+ G C NT GSF C+ C G P+
Sbjct: 795 ALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE 852
Query: 239 RLSCKDIDECSITSGICSNG-ACENQMGTYQC-----VCDEGYAQSTVKSHXXXXXXXXX 292
+C DI+EC+ S C G +C N +G+Y C +C GY S
Sbjct: 853 G-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECET 911
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDEC-AGGARPCGGGQCRNTVGS 349
RC C N PGSY C C+ G+ A GR C D++EC A R C C NT+GS
Sbjct: 912 GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGS 970
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
Y C+C G + +A G + C+D++EC E Q+ C C N
Sbjct: 971 YRCSCASGFLLAADGKR--CEDVNEC-------------EAQR---------CSQ-ECAN 1005
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD-GWR- 467
GS+ C C GY + E G CTD DEC G C+N+PGS+QC C + G+
Sbjct: 1006 IYGSYQCYCRQGYQLA-EDGHTCTDIDECAQGA-GILCTFRCLNVPGSYQCACPEQGYTM 1063
Query: 468 -GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLRTVCCVYSC 523
+G +C+DVDEC C TC N GSFRCL C Y +T C +C
Sbjct: 1064 TANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVS---KTKCERTTC 1120
Query: 524 VDIDECANDP 533
D EC N P
Sbjct: 1121 HDFLECQNSP 1130
Score = 220 bits (538), Expect = 9e-57
Identities = 153/445 (34%), Positives = 199/445 (44%), Gaps = 67/445 (15%)
Query: 134 CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTC--H---C 187
C + G C CFPGY + +C D +EC + C C NT GSF C H C
Sbjct: 693 CSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLC 752
Query: 188 RPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRC----ECGHGMELAPDRLSC 242
GY + K CVDI+EC + C RG CVNT GSF C C G L C
Sbjct: 753 ADGYILNAHRK-CVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG--EC 809
Query: 243 KDIDECSITSGICSNG-ACENQMGTYQCV----CDEGYAQSTVKSHXXXXXXXXXXXXRC 297
+D+DEC++ + C G C+N G++ C C +G+ Q + + C
Sbjct: 810 EDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDP-EGNCVDINECTSLSEPC 868
Query: 298 Q--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGS 349
+ SC+NT GSY C C G+H DG C D++EC G CG GQ C N GS
Sbjct: 869 RPGFSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQVCHNLPGS 928
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
Y C C G A G C D++EC P LC +C N
Sbjct: 929 YRCDCKAGFQRDAFGR--GCIDVNEC-----------------WASP--GRLC-QHTCEN 966
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-- 467
T+GS+ C C G+ + + G C D +ECE C + +C N+ GS+QC CR G++
Sbjct: 967 TLGSYRCSCASGFLLAAD-GKRCEDVNECEAQRC----SQECANIYGSYQCYCRQGYQLA 1021
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC-DTGYKGDGYGLRTVCCVYSCVDI 526
DG TC D+DEC G C N GS++C C + GY G SC D+
Sbjct: 1022 EDGHTCTDIDEC-AQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG-------RSCKDV 1073
Query: 527 DECANDPTLCENGH-CSNTPGGYEC 550
DECA C C N G + C
Sbjct: 1074 DECALGTHNCSEAETCHNIQGSFRC 1098
Score = 207 bits (506), Expect = 7e-53
Identities = 132/363 (36%), Positives = 168/363 (46%), Gaps = 48/363 (13%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC----DCFPGYEKDSKNHTCVDVNECEIVDGVC 171
+++NEC C G C N LG F C C PGY K+ C DV+EC + C
Sbjct: 765 VDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL--KDGECEDVDECAMGTHTC 822
Query: 172 GDGD-CHNTEGSFTCH----CRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSF 225
G C NT+GSF C C G+ D CVDI+EC CR G C+NT GS+
Sbjct: 823 QPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGSY 881
Query: 226 RCE-----CGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQST 279
C+ C G + D C D++EC C G C N G+Y+C C G+ +
Sbjct: 882 TCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDA 941
Query: 280 VKSHXXXXXXXXXXXXR-CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC 338
R CQH+C NT GSY C+C G+ L ADG+ C D++EC A+ C
Sbjct: 942 FGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE--AQRC 999
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQI 398
+C N GSY C C G + G TC DIDECA
Sbjct: 1000 SQ-ECANIYGSYQCYCRQGYQLAEDGH--TCTDIDECAQGAGI----------------- 1039
Query: 399 PELCGAGSCHNTIGSFVCQCPD-GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
LC C N GS+ C CP+ GY++ G +C D DEC LGT +C A C N+ GS
Sbjct: 1040 --LC-TFRCLNVPGSYQCACPEQGYTMTAN-GRSCKDVDECALGTHNCSEAETCHNIQGS 1095
Query: 458 FQC 460
F+C
Sbjct: 1096 FRC 1098
Score = 199 bits (486), Expect = 2e-50
Identities = 155/475 (32%), Positives = 209/475 (44%), Gaps = 82/475 (17%)
Query: 120 NECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
+EC PG LC H C N +G + C CFPG+ TC +G
Sbjct: 606 DECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRP------------EGHPPQ 652
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDE---CADNDALCRGGRCVNTAGSFRCECGHGMEL 235
E + + + I + + + C DN C+ C GS C C G +
Sbjct: 653 PEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGP-CK-QVCSTVGGSAICSCFPGYAI 710
Query: 236 APDRLSCKDIDECSITSGICSNGA-CENQMGTYQCV-----CDEGYAQSTVKS--HXXXX 287
D +SC+D DEC + + CS C N +G++ CV C +GY + +
Sbjct: 711 MADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINEC 770
Query: 288 XXXXXXXXRCQHSCVNTPGSYHC----TCREGWHLRADGRSCRDIDECAGGARPCGGG-Q 342
R +H CVNT GS+HC TC G+ L+ DG C D+DECA G C G
Sbjct: 771 VTDLHTCSRGEH-CVNTLGSFHCYKALTCEPGYALK-DG-ECEDVDECAMGTHTCQPGFL 827
Query: 343 CRNTVGSYTC----TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQI 398
C+NT GS+ C C DG + G C DI+EC L
Sbjct: 828 CQNTKGSFYCQARQRCMDGFLQDPEG---NCVDINECTSL-------------------- 864
Query: 399 PELCGAG-SCHNTIGSFVCQ-----CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCI 452
E C G SC NT+GS+ CQ C GY + G C D +ECE G C C
Sbjct: 865 SEPCRPGFSCINTVGSYTCQRNPLICARGYHAS-DDGXKCVDVNECETGVHRCGEGQVCH 923
Query: 453 NLPGSFQCRCRDGWRGD--GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
NLPGS++C C+ G++ D G C DV+EC + G + TC NT GS+RC C +G+
Sbjct: 924 NLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL-CQHTCENTLGSYRCSCASGFLLA 982
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G R C D++EC + C C+N G Y+C C G+ A DG +C
Sbjct: 983 ADGKR-------CEDVNEC--EAQRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTC 1027
Score = 190 bits (463), Expect = 1e-47
Identities = 148/437 (33%), Positives = 186/437 (42%), Gaps = 74/437 (16%)
Query: 156 HTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC-R 214
+TC D C+ V C GS C C PGY C D DEC C R
Sbjct: 681 NTCKDNGPCKQV--------CSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSR 732
Query: 215 GGRCVNTAGSFRCE-----CGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQ 268
CVNT GSF C C G L R C DI+EC CS G C N +G++
Sbjct: 733 RQFCVNTLGSFYCVNHTVLCADGYILNAHR-KCVDINECVTDLHTCSRGEHCVNTLGSFH 791
Query: 269 C----VCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCT----CREGWHLRA 320
C C+ GYA + + C NT GS++C C +G+
Sbjct: 792 CYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDP 851
Query: 321 DGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCT-----CTDGLVPSAAGAKPTCQDIDE 374
+G +C DI+EC + PC G C NTVGSYTC C G S G K C D++E
Sbjct: 852 EG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGXK--CVDVNE 908
Query: 375 CADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACT 433
C + CG G CHN GS+ C C G+ + G C
Sbjct: 909 CETGVHR--------------------CGEGQVCHNLPGSYRCDCKAGFQ-RDAFGRGCI 947
Query: 434 DDDEC--ELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPR 489
D +EC G H C N GS++C C G+ DG CEDV+EC C
Sbjct: 948 DVNECWASPGRLCQHT---CENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQE 1002
Query: 490 ATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYE 549
CAN GS++C C GY+ G ++C DIDECA + C N PG Y+
Sbjct: 1003 --CANIYGSYQCYCRQGYQLAEDG-------HTCTDIDECAQGAGILCTFRCLNVPGSYQ 1053
Query: 550 CDC-DVGFTRAADGRSC 565
C C + G+T A+GRSC
Sbjct: 1054 CACPEQGYTMTANGRSC 1070
Score = 170 bits (414), Expect = 1e-41
Identities = 134/427 (31%), Positives = 175/427 (40%), Gaps = 63/427 (14%)
Query: 160 DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCV 219
D +EC ++ G C NT GS+ C C PG+ D + C +A
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA--- 660
Query: 220 NTAGSFRCECGHGMEL-APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYA-- 276
F + + L P +CKD +G C C G+ C C GYA
Sbjct: 661 -LKSEFSQVASNTIPLPLPQPNTCKD-------NGPCKQ-VCSTVGGSAICSCFPGYAIM 711
Query: 277 QSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCT-----CREGWHLRADGRSCRDIDEC 331
V + CVNT GS++C C +G+ L A R C DI+EC
Sbjct: 712 ADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINEC 770
Query: 332 AGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
C G+ C NT+GS+ C P A C+D+DECA M
Sbjct: 771 VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECA--------MGTHTC 822
Query: 391 QKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCDCH 446
Q C NT GSF CQ C DG+ PE C D +EC + C
Sbjct: 823 QPGF-----------LCQNTKGSFYCQARQRCMDGFLQDPEGN--CVDINECTSLSEPCR 869
Query: 447 PAADCINLPGSFQCR-----CRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTDGSF 499
P CIN GS+ C+ C G+ DG C DV+EC T C C N GS+
Sbjct: 870 PGFSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQVCHNLPGSY 929
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDEC-ANDPTLCENGHCSNTPGGYECDCDVGFTR 558
RC C G++ D +G C+D++EC A+ LC++ C NT G Y C C GF
Sbjct: 930 RCDCKAGFQRDAFG-------RGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLL 981
Query: 559 AADGRSC 565
AADG+ C
Sbjct: 982 AADGKRC 988
Score = 165 bits (401), Expect = 4e-40
Identities = 107/292 (36%), Positives = 133/292 (45%), Gaps = 55/292 (18%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C+ C GS C+C G+ + ADG SC D DEC GA C Q C NT+GS+ C
Sbjct: 689 CKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNH 748
Query: 354 ---CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHN 409
C DG + A C DI+EC + T C G C N
Sbjct: 749 TVLCADGYI---LNAHRKCVDINECVTDLHT--------------------CSRGEHCVN 785
Query: 410 TIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC----R 461
T+GSF C C GY++K + C D DEC +GT C P C N GSF C R
Sbjct: 786 TLGSFHCYKALTCEPGYALKDGE---CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR 842
Query: 462 CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSFRC-----LCDTGYKGDGYGLR 515
C DG+ D C D++EC + + C P +C NT GS+ C +C GY G +
Sbjct: 843 CMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGXK 902
Query: 516 TVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTRAADGRSCL 566
CVD++EC C G C N PG Y CDC GF R A GR C+
Sbjct: 903 -------CVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 947
Score = 129 bits (311), Expect = 3e-29
Identities = 65/167 (38%), Positives = 89/167 (53%), Gaps = 10/167 (5%)
Query: 117 MEVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++VNEC A PG LC H C N LG + C C G+ + C DVNECE C +
Sbjct: 947 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQ-E 1002
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHGME 234
C N GS+ C+CR GY+ + C DIDECA + RC+N GS++C C G
Sbjct: 1003 CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYT 1062
Query: 235 LAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCV---CDEGYAQ 277
+ + SCKD+DEC++ + CS C N G+++C+ C Y Q
Sbjct: 1063 MTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQ 1109
Score = 128 bits (309), Expect = 5e-29
Identities = 95/304 (31%), Positives = 123/304 (40%), Gaps = 49/304 (16%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
CQH C+NT GSYHC C G+ L+ DGR+CR G P + S
Sbjct: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCR-----PEGHPPQPEAPQEPALKSEFSQVAS 670
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDE-------LQKSVDPQIPELCGAGS--- 406
+P TC+D C + ST+ ++ + V + + C G+
Sbjct: 671 NTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDC 730
Query: 407 -----CHNTIGSFVC-----QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPG 456
C NT+GSF C C DGY + + C D +EC C C+N G
Sbjct: 731 SRRQFCVNTLGSFYCVNHTVLCADGYILNAHR--KCVDINECVTDLHTCSRGEHCVNTLG 788
Query: 457 SFQC----RCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRC----LCDTGYK 508
SF C C G+ CEDVDEC C P C NT GSF C C G+
Sbjct: 789 SFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFL 848
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECD-----CDVGFTRAADG 562
D G +CVDI+EC + C G C NT G Y C C G+ + DG
Sbjct: 849 QDPEG--------NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 900
Query: 563 RSCL 566
C+
Sbjct: 901 XKCV 904
>X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein.
Length = 683
Score = 222 bits (543), Expect = 2e-57
Identities = 142/413 (34%), Positives = 189/413 (45%), Gaps = 60/413 (14%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCE----CG 230
C +T C C GY+ C D++EC CR G C+NT GSFRC+ CG
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG 249
Query: 231 HGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQC----VCDEGYAQSTVKSHXX 285
G EL D SCKDIDEC C + C+N +G+++C C G+ Q + +
Sbjct: 250 TGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL-GNCI 307
Query: 286 XXXXXXXXXXRCQ--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPC 338
C H+C+NT GSY C C G+HL +G C D+DECA A PC
Sbjct: 308 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Query: 339 GGG-QCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
G G +C N+ GS+ C C G G C D++EC
Sbjct: 368 GKGHRCVNSPGSFRCECKTGYYFD--GISRMCVDVNECQRYPG----------------- 408
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
LCG C NT+GS++C C G+ + + G +C D +EC C + +C N+ GS
Sbjct: 409 --RLCGH-KCENTLGSYLCSCSVGFRLSVD-GRSCEDINECSSSPC----SQECANVYGS 460
Query: 458 FQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+QC CR G++ DG TCED+DEC GG C N GSF+C C + G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS------GY 514
Query: 515 RTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYEC---DCDVGFTRAADGR 563
R +C DIDEC C N C N G + C +C + R+A R
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSAATR 567
Score = 214 bits (522), Expect = 8e-55
Identities = 151/435 (34%), Positives = 192/435 (44%), Gaps = 56/435 (12%)
Query: 133 RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----C 187
+CR+ C CF GY+ S +C DVNEC C G+ C NT GSF C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC----ECGHGMELAPDRL-S 241
GY+ + C DIDEC C C NT GSFRC +C G D L +
Sbjct: 249 GTGYELTE-DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG--FIQDALGN 305
Query: 242 CKDIDECSITSGICSNG-ACENQMGTYQCV-----CDEGYAQSTVKSHXXXXXXXXXXXX 295
C DI+EC S C G C N G+Y C C GY + +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H CVN+PGS+ C C+ G++ R C D++EC G +C NT+GSY C+
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C+ G S G +C+DI+EC S P C + C N GS
Sbjct: 426 CSVGFRLSVDGR--SCEDINEC-----------------SSSP-----C-SQECANVYGS 460
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDGWR--GDG 470
+ C C GY + G C D DEC L T + CIN+PGSFQC C G+R +G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG 520
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLRTVCCVYSCVDID 527
C+D+DEC+T C TC N G+FRCL C Y+ T C C +
Sbjct: 521 RNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSA---ATRCERLPCHENR 577
Query: 528 ECANDPTLCENGHCS 542
EC+ P H S
Sbjct: 578 ECSKLPLRITYYHLS 592
Score = 182 bits (444), Expect = 2e-45
Identities = 102/279 (36%), Positives = 138/279 (49%), Gaps = 20/279 (7%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC-----DCFPGYEKDSKNHTCVDVNECEIVDGV 170
+++NEC + C G C N G +TC +C GY + + CVDV+EC
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 171 CGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC 229
CG G C N+ GSF C C+ GY D S++CVD++EC G +C NT GS+ C C
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSC 426
Query: 230 GHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS---HXXX 286
G L+ D SC+DI+ECS S CS C N G+YQC C GY S V
Sbjct: 427 SVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDID 483
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDECAGGARPCGGGQ-CR 344
C + C+N PGS+ C+C G+ L +GR+C+DIDEC G C + C
Sbjct: 484 ECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF 543
Query: 345 NTVGSYTC---TCTDGLVPSAAG--AKPTCQDIDECADL 378
N G++ C C + SAA + C + EC+ L
Sbjct: 544 NIQGAFRCLAFECPENYRRSAATRCERLPCHENRECSKL 582
Score = 155 bits (377), Expect = 3e-37
Identities = 129/379 (34%), Positives = 175/379 (46%), Gaps = 61/379 (16%)
Query: 213 CRGG-----RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGT 266
CRGG +C +T C C G +L D +SC+D++EC S C G +C N +G+
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 239
Query: 267 YQC----VCDEGYAQSTVKSHXXXXXXXXXXXXRC--QHSCVNTPGSYHC----TCREGW 316
++C C GY + T + C C NT GS+ C C+ G+
Sbjct: 240 FRCQRDSSCGTGY-ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Query: 317 HLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
A G +C DI+EC + PC G C NT GSYTC VP+ ++ C
Sbjct: 299 IQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN---VPNCGRGYHLNEEGTRC 354
Query: 376 ADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTIGSFVCQCPDGYSVKPEQGPACTD 434
D VDE +P CG G C N+ GSF C+C GY C D
Sbjct: 355 VD---------VDECAPPAEP-----CGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVD 399
Query: 435 DDECEL--GTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRA 490
+EC+ G H C N GS+ C C G+R DG +CED++EC ++ C
Sbjct: 400 VNECQRYPGRLCGH---KCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQE- 453
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT---LCENGHCSNTPGG 547
CAN GS++C C GY+ L V V +C DIDECA PT +C + C N PG
Sbjct: 454 -CANVYGSYQCYCRRGYQ-----LSDVDGV-TCEDIDECAL-PTGGHIC-SYRCINIPGS 504
Query: 548 YECDC-DVGFTRAADGRSC 565
++C C G+ A +GR+C
Sbjct: 505 FQCSCPSSGYRLAPNGRNC 523
Score = 130 bits (313), Expect = 2e-29
Identities = 87/248 (35%), Positives = 118/248 (47%), Gaps = 37/248 (14%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
D C GG PC QCR+T C+C G + G +C+D++EC
Sbjct: 178 DRCRGGG-PCKQ-QCRDTGDEVVCSCFVGYQLLSDGV--SCEDVNEC------------- 220
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCD 444
+ S ++ E SC NT+GSF CQ C GY + + +C D DECE G +
Sbjct: 221 -ITGSHSCRLGE-----SCINTVGSFRCQRDSSCGTGYELTEDN--SCKDIDECESGIHN 272
Query: 445 CHPAADCINLPGSFQCR----CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSF 499
C P C N GSF+CR C+ G+ D C D++ECL+ + C TC NT+GS+
Sbjct: 273 CLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSY 332
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTR 558
C + G GY L CVD+DECA C GH C N+PG + C+C G+
Sbjct: 333 TCQKNVPNCGRGYHLNEEGT--RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 559 AADGRSCL 566
R C+
Sbjct: 391 DGISRMCV 398
>X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein.
Length = 601
Score = 222 bits (542), Expect = 3e-57
Identities = 141/410 (34%), Positives = 188/410 (45%), Gaps = 60/410 (14%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCE----CG 230
C +T C C GY+ C D++EC CR G C+NT GSFRC+ CG
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG 249
Query: 231 HGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQC----VCDEGYAQSTVKSHXX 285
G EL D SCKDIDEC C + C+N +G+++C C G+ Q + +
Sbjct: 250 TGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL-GNCI 307
Query: 286 XXXXXXXXXXRCQ--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPC 338
C H+C+NT GSY C C G+HL +G C D+DECA A PC
Sbjct: 308 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Query: 339 GGG-QCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
G G +C N+ GS+ C C G G C D++EC
Sbjct: 368 GKGHRCVNSPGSFRCECKTGYYFD--GISRMCVDVNECQRYPG----------------- 408
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
LCG C NT+GS++C C G+ + + G +C D +EC C + +C N+ GS
Sbjct: 409 --RLCGH-KCENTLGSYLCSCSVGFRLSVD-GRSCEDINECSSSPC----SQECANVYGS 460
Query: 458 FQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+QC CR G++ DG TCED+DEC GG C N GSF+C C + G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS------GY 514
Query: 515 RTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYEC---DCDVGFTRAA 560
R +C DIDEC C N C N G + C +C + R+A
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSA 564
Score = 211 bits (516), Expect = 4e-54
Identities = 143/401 (35%), Positives = 182/401 (45%), Gaps = 53/401 (13%)
Query: 133 RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----C 187
+CR+ C CF GY+ S +C DVNEC C G+ C NT GSF C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC----ECGHGMELAPDRL-S 241
GY+ + C DIDEC C C NT GSFRC +C G D L +
Sbjct: 249 GTGYELTE-DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG--FIQDALGN 305
Query: 242 CKDIDECSITSGICSNG-ACENQMGTYQCV-----CDEGYAQSTVKSHXXXXXXXXXXXX 295
C DI+EC S C G C N G+Y C C GY + +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H CVN+PGS+ C C+ G++ R C D++EC G +C NT+GSY C+
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C+ G S G +C+DI+EC S P C + C N GS
Sbjct: 426 CSVGFRLSVDGR--SCEDINEC-----------------SSSP-----C-SQECANVYGS 460
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDGWR--GDG 470
+ C C GY + G C D DEC L T + CIN+PGSFQC C G+R +G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG 520
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYK 508
C+D+DEC+T C TC N G+FRCL C Y+
Sbjct: 521 RNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYR 561
Score = 205 bits (501), Expect = 3e-52
Identities = 135/377 (35%), Positives = 171/377 (45%), Gaps = 48/377 (12%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCD----CFPGYEKDSKNHTCVDVNECEI-VDGVC 171
+VNEC C G C N +G F C C GYE N +C D++ECE +
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCL 274
Query: 172 GDGDCHNTEGSFTCH----CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR 226
D C NT GSF C C+ G+ D C+DI+EC A C G C+NT GS+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 227 CE-----CGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTV 280
C+ CG G L + C D+DEC+ + C G C N G+++C C GY +
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 281 KSHXXXXXXXXXXXXR-CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
R C H C NT GSY C+C G+ L DGRSC DI+EC+ PC
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSS--PCS 451
Query: 340 GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIP 399
+C N GSY C C G S TC+DIDECA P
Sbjct: 452 Q-ECANVYGSYQCYCRRGYQLSDVDGV-TCEDIDECA------------------LPTGG 491
Query: 400 ELCGAGSCHNTIGSFVCQCP-DGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
+C + C N GSF C CP GY + P G C D DEC G +C C N+ G+F
Sbjct: 492 HIC-SYRCINIPGSFQCSCPSSGYRLAP-NGRNCQDIDECVTGIHNCSINETCFNIQGAF 549
Query: 459 QC---RCRDGWRGDGAT 472
+C C + +R AT
Sbjct: 550 RCLAFECPENYRRSAAT 566
Score = 181 bits (440), Expect = 7e-45
Identities = 99/265 (37%), Positives = 132/265 (49%), Gaps = 18/265 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC-----DCFPGYEKDSKNHTCVDVNECEIVDGV 170
+++NEC + C G C N G +TC +C GY + + CVDV+EC
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 171 CGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC 229
CG G C N+ GSF C C+ GY D S++CVD++EC G +C NT GS+ C C
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSC 426
Query: 230 GHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS---HXXX 286
G L+ D SC+DI+ECS S CS C N G+YQC C GY S V
Sbjct: 427 SVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDID 483
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDECAGGARPCGGGQ-CR 344
C + C+N PGS+ C+C G+ L +GR+C+DIDEC G C + C
Sbjct: 484 ECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF 543
Query: 345 NTVGSYTC---TCTDGLVPSAAGAK 366
N G++ C C + SAA K
Sbjct: 544 NIQGAFRCLAFECPENYRRSAATQK 568
Score = 155 bits (377), Expect = 3e-37
Identities = 129/379 (34%), Positives = 175/379 (46%), Gaps = 61/379 (16%)
Query: 213 CRGG-----RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGT 266
CRGG +C +T C C G +L D +SC+D++EC S C G +C N +G+
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 239
Query: 267 YQC----VCDEGYAQSTVKSHXXXXXXXXXXXXRC--QHSCVNTPGSYHC----TCREGW 316
++C C GY + T + C C NT GS+ C C+ G+
Sbjct: 240 FRCQRDSSCGTGY-ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Query: 317 HLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
A G +C DI+EC + PC G C NT GSYTC VP+ ++ C
Sbjct: 299 IQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN---VPNCGRGYHLNEEGTRC 354
Query: 376 ADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTIGSFVCQCPDGYSVKPEQGPACTD 434
D VDE +P CG G C N+ GSF C+C GY C D
Sbjct: 355 VD---------VDECAPPAEP-----CGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVD 399
Query: 435 DDECEL--GTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRA 490
+EC+ G H C N GS+ C C G+R DG +CED++EC ++ C
Sbjct: 400 VNECQRYPGRLCGH---KCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQE- 453
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT---LCENGHCSNTPGG 547
CAN GS++C C GY+ L V V +C DIDECA PT +C + C N PG
Sbjct: 454 -CANVYGSYQCYCRRGYQ-----LSDVDGV-TCEDIDECAL-PTGGHIC-SYRCINIPGS 504
Query: 548 YECDC-DVGFTRAADGRSC 565
++C C G+ A +GR+C
Sbjct: 505 FQCSCPSSGYRLAPNGRNC 523
Score = 130 bits (313), Expect = 2e-29
Identities = 87/248 (35%), Positives = 118/248 (47%), Gaps = 37/248 (14%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
D C GG PC QCR+T C+C G + G +C+D++EC
Sbjct: 178 DRCRGGG-PCKQ-QCRDTGDEVVCSCFVGYQLLSDGV--SCEDVNEC------------- 220
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCD 444
+ S ++ E SC NT+GSF CQ C GY + + +C D DECE G +
Sbjct: 221 -ITGSHSCRLGE-----SCINTVGSFRCQRDSSCGTGYELTEDN--SCKDIDECESGIHN 272
Query: 445 CHPAADCINLPGSFQCR----CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSF 499
C P C N GSF+CR C+ G+ D C D++ECL+ + C TC NT+GS+
Sbjct: 273 CLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSY 332
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTR 558
C + G GY L CVD+DECA C GH C N+PG + C+C G+
Sbjct: 333 TCQKNVPNCGRGYHLNEEGT--RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 559 AADGRSCL 566
R C+
Sbjct: 391 DGISRMCV 398
>X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein.
Length = 566
Score = 222 bits (542), Expect = 3e-57
Identities = 141/410 (34%), Positives = 188/410 (45%), Gaps = 60/410 (14%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCE----CG 230
C +T C C GY+ C D++EC CR G C+NT GSFRC+ CG
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG 249
Query: 231 HGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQC----VCDEGYAQSTVKSHXX 285
G EL D SCKDIDEC C + C+N +G+++C C G+ Q + +
Sbjct: 250 TGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL-GNCI 307
Query: 286 XXXXXXXXXXRCQ--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPC 338
C H+C+NT GSY C C G+HL +G C D+DECA A PC
Sbjct: 308 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Query: 339 GGG-QCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
G G +C N+ GS+ C C G G C D++EC
Sbjct: 368 GKGHRCVNSPGSFRCECKTGYYFD--GISRMCVDVNECQRYPG----------------- 408
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
LCG C NT+GS++C C G+ + + G +C D +EC C + +C N+ GS
Sbjct: 409 --RLCGH-KCENTLGSYLCSCSVGFRLSVD-GRSCEDINECSSSPC----SQECANVYGS 460
Query: 458 FQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+QC CR G++ DG TCED+DEC GG C N GSF+C C + G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS------GY 514
Query: 515 RTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYEC---DCDVGFTRAA 560
R +C DIDEC C N C N G + C +C + R+A
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSA 564
Score = 211 bits (516), Expect = 4e-54
Identities = 143/401 (35%), Positives = 183/401 (45%), Gaps = 53/401 (13%)
Query: 133 RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----C 187
+CR+ C CF GY+ S +C DVNEC C G+ C NT GSF C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRC----ECGHGMELAPDRL-S 241
GY+ + + C DIDEC C C NT GSFRC +C G D L +
Sbjct: 249 GTGYELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF--IQDALGN 305
Query: 242 CKDIDECSITSGICSNG-ACENQMGTYQCV-----CDEGYAQSTVKSHXXXXXXXXXXXX 295
C DI+EC S C G C N G+Y C C GY + +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 296 RCQ--HSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H CVN+PGS+ C C+ G++ R C D++EC G +C NT+GSY C+
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C+ G S G +C+DI+EC S P C + C N GS
Sbjct: 426 CSVGFRLSVDGR--SCEDINEC-----------------SSSP-----C-SQECANVYGS 460
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDGWR--GDG 470
+ C C GY + G C D DEC L T + CIN+PGSFQC C G+R +G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG 520
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYK 508
C+D+DEC+T C TC N G+FRCL C Y+
Sbjct: 521 RNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYR 561
Score = 205 bits (501), Expect = 3e-52
Identities = 135/377 (35%), Positives = 171/377 (45%), Gaps = 48/377 (12%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCD----CFPGYEKDSKNHTCVDVNECEI-VDGVC 171
+VNEC C G C N +G F C C GYE N +C D++ECE +
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCL 274
Query: 172 GDGDCHNTEGSFTCH----CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR 226
D C NT GSF C C+ G+ D C+DI+EC A C G C+NT GS+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 227 CE-----CGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTV 280
C+ CG G L + C D+DEC+ + C G C N G+++C C GY +
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 281 KSHXXXXXXXXXXXXR-CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
R C H C NT GSY C+C G+ L DGRSC DI+EC+ PC
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSS--PCS 451
Query: 340 GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIP 399
+C N GSY C C G S TC+DIDECA P
Sbjct: 452 Q-ECANVYGSYQCYCRRGYQLSDVDG-VTCEDIDECA------------------LPTGG 491
Query: 400 ELCGAGSCHNTIGSFVCQCP-DGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
+C + C N GSF C CP GY + P G C D DEC G +C C N+ G+F
Sbjct: 492 HIC-SYRCINIPGSFQCSCPSSGYRLAP-NGRNCQDIDECVTGIHNCSINETCFNIQGAF 549
Query: 459 QC---RCRDGWRGDGAT 472
+C C + +R AT
Sbjct: 550 RCLAFECPENYRRSAAT 566
Score = 180 bits (438), Expect = 1e-44
Identities = 94/248 (37%), Positives = 126/248 (50%), Gaps = 15/248 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC-----DCFPGYEKDSKNHTCVDVNECEIVDGV 170
+++NEC + C G C N G +TC +C GY + + CVDV+EC
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 171 CGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC 229
CG G C N+ GSF C C+ GY D S++CVD++EC G +C NT GS+ C C
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSC 426
Query: 230 GHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS---HXXX 286
G L+ D SC+DI+ECS S CS C N G+YQC C GY S V
Sbjct: 427 SVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDID 483
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDECAGGARPCGGGQ-CR 344
C + C+N PGS+ C+C G+ L +GR+C+DIDEC G C + C
Sbjct: 484 ECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF 543
Query: 345 NTVGSYTC 352
N G++ C
Sbjct: 544 NIQGAFRC 551
Score = 153 bits (372), Expect = 1e-36
Identities = 101/283 (35%), Positives = 133/283 (46%), Gaps = 43/283 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCT 355
C+ C +T C+C G+ L +DG SC D++EC G+ C G+ C NTVGS+ C
Sbjct: 186 CKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRD 245
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
S+ G + + C D +DE + + +P+ C NT+GSF
Sbjct: 246 -----SSCGTGYELTEDNSCKD---------IDECESGIHNCLPDFI----CQNTLGSFR 287
Query: 416 C----QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR-----CRDGW 466
C QC G+ ++ G C D +EC + C CIN GS+ C+ C G+
Sbjct: 288 CRPKLQCKSGF-IQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 467 R--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+G C DVDEC C C N+ GSFRC C TGY DG CV
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRM-------CV 398
Query: 525 DIDECANDP-TLCENGH-CSNTPGGYECDCDVGFTRAADGRSC 565
D++EC P LC GH C NT G Y C C VGF + DGRSC
Sbjct: 399 DVNECQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 130 bits (313), Expect = 2e-29
Identities = 87/248 (35%), Positives = 118/248 (47%), Gaps = 37/248 (14%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
D C GG PC QCR+T C+C G + G +C+D++EC
Sbjct: 178 DRCRGGG-PCKQ-QCRDTGDEVVCSCFVGYQLLSDGV--SCEDVNEC------------- 220
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCD 444
+ S ++ E SC NT+GSF CQ C GY + + +C D DECE G +
Sbjct: 221 -ITGSHSCRLGE-----SCINTVGSFRCQRDSSCGTGYELTEDN--SCKDIDECESGIHN 272
Query: 445 CHPAADCINLPGSFQCR----CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSF 499
C P C N GSF+CR C+ G+ D C D++ECL+ + C TC NT+GS+
Sbjct: 273 CLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSY 332
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTR 558
C + G GY L CVD+DECA C GH C N+PG + C+C G+
Sbjct: 333 TCQKNVPNCGRGYHLNEEGT--RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 559 AADGRSCL 566
R C+
Sbjct: 391 DGISRMCV 398
>U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein.
Length = 703
Score = 222 bits (542), Expect = 3e-57
Identities = 141/410 (34%), Positives = 188/410 (45%), Gaps = 60/410 (14%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCE----CG 230
C +T C C GY+ C D++EC CR G C+NT GSFRC+ CG
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG 249
Query: 231 HGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQC----VCDEGYAQSTVKSHXX 285
G EL D SCKDIDEC C + C+N +G+++C C G+ Q + +
Sbjct: 250 TGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL-GNCI 307
Query: 286 XXXXXXXXXXRCQ--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPC 338
C H+C+NT GSY C C G+HL +G C D+DECA A PC
Sbjct: 308 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Query: 339 GGG-QCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
G G +C N+ GS+ C C G G C D++EC
Sbjct: 368 GKGHRCVNSPGSFRCECKTGYYFD--GISRMCVDVNECQRYPG----------------- 408
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
LCG C NT+GS++C C G+ + + G +C D +EC C + +C N+ GS
Sbjct: 409 --RLCGH-KCENTLGSYLCSCSVGFRLSVD-GRSCEDINECSSSPC----SQECANVYGS 460
Query: 458 FQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+QC CR G++ DG TCED+DEC GG C N GSF+C C + G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS------GY 514
Query: 515 RTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYEC---DCDVGFTRAA 560
R +C DIDEC C N C N G + C +C + R+A
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSA 564
Score = 217 bits (531), Expect = 7e-56
Identities = 153/432 (35%), Positives = 194/432 (44%), Gaps = 59/432 (13%)
Query: 133 RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----C 187
+CR+ C CF GY+ S +C DVNEC C G+ C NT GSF C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC----ECGHGMELAPDRL-S 241
GY+ + C DIDEC C C NT GSFRC +C G D L +
Sbjct: 249 GTGYELTE-DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG--FIQDALGN 305
Query: 242 CKDIDECSITSGICSNG-ACENQMGTYQCV-----CDEGYAQSTVKSHXXXXXXXXXXXX 295
C DI+EC S C G C N G+Y C C GY + +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H CVN+PGS+ C C+ G++ R C D++EC G +C NT+GSY C+
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C+ G S G +C+DI+EC S P C + C N GS
Sbjct: 426 CSVGFRLSVDGR--SCEDINEC-----------------SSSP-----C-SQECANVYGS 460
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDGWR--GDG 470
+ C C GY + G C D DEC L T + CIN+PGSFQC C G+R +G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG 520
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLR-----TVCCVYS 522
C+D+DEC+T C TC N G+FRCL C Y+ L+ TV C+ S
Sbjct: 521 RNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSAATLQQEKTDTVRCIKS 580
Query: 523 CVDID-ECANDP 533
C D C DP
Sbjct: 581 CRPNDVTCVFDP 592
Score = 206 bits (503), Expect = 2e-52
Identities = 141/402 (35%), Positives = 180/402 (44%), Gaps = 56/402 (13%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCD----CFPGYEKDSKNHTCVDVNECEI-VDGVC 171
+VNEC C G C N +G F C C GYE N +C D++ECE +
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCL 274
Query: 172 GDGDCHNTEGSFTCH----CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR 226
D C NT GSF C C+ G+ D C+DI+EC A C G C+NT GS+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 227 CE-----CGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTV 280
C+ CG G L + C D+DEC+ + C G C N G+++C C GY +
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 281 KSHXXXXXXXXXXXXR-CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
R C H C NT GSY C+C G+ L DGRSC DI+EC+ PC
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSS--PCS 451
Query: 340 GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIP 399
+C N GSY C C G S TC+DIDECA P
Sbjct: 452 Q-ECANVYGSYQCYCRRGYQLSDVDGV-TCEDIDECA------------------LPTGG 491
Query: 400 ELCGAGSCHNTIGSFVCQCP-DGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
+C + C N GSF C CP GY + P G C D DEC G +C C N+ G+F
Sbjct: 492 HIC-SYRCINIPGSFQCSCPSSGYRLAP-NGRNCQDIDECVTGIHNCSINETCFNIQGAF 549
Query: 459 QC---RCRDGWRGDGATCE----DVDECLTNNGGCHPR-ATC 492
+C C + +R AT + D C+ + C P TC
Sbjct: 550 RCLAFECPENYRRSAATLQQEKTDTVRCIKS---CRPNDVTC 588
Score = 181 bits (441), Expect = 5e-45
Identities = 100/274 (36%), Positives = 134/274 (48%), Gaps = 18/274 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC-----DCFPGYEKDSKNHTCVDVNECEIVDGV 170
+++NEC + C G C N G +TC +C GY + + CVDV+EC
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 171 CGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC 229
CG G C N+ GSF C C+ GY D S++CVD++EC G +C NT GS+ C C
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSC 426
Query: 230 GHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS---HXXX 286
G L+ D SC+DI+ECS S CS C N G+YQC C GY S V
Sbjct: 427 SVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDID 483
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDECAGGARPCGGGQ-CR 344
C + C+N PGS+ C+C G+ L +GR+C+DIDEC G C + C
Sbjct: 484 ECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF 543
Query: 345 NTVGSYTC---TCTDGLVPSAAGAKPTCQDIDEC 375
N G++ C C + SAA + D C
Sbjct: 544 NIQGAFRCLAFECPENYRRSAATLQQEKTDTVRC 577
Score = 155 bits (377), Expect = 3e-37
Identities = 129/379 (34%), Positives = 175/379 (46%), Gaps = 61/379 (16%)
Query: 213 CRGG-----RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGT 266
CRGG +C +T C C G +L D +SC+D++EC S C G +C N +G+
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 239
Query: 267 YQC----VCDEGYAQSTVKSHXXXXXXXXXXXXRC--QHSCVNTPGSYHC----TCREGW 316
++C C GY + T + C C NT GS+ C C+ G+
Sbjct: 240 FRCQRDSSCGTGY-ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Query: 317 HLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
A G +C DI+EC + PC G C NT GSYTC VP+ ++ C
Sbjct: 299 IQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN---VPNCGRGYHLNEEGTRC 354
Query: 376 ADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTIGSFVCQCPDGYSVKPEQGPACTD 434
D VDE +P CG G C N+ GSF C+C GY C D
Sbjct: 355 VD---------VDECAPPAEP-----CGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVD 399
Query: 435 DDECEL--GTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRA 490
+EC+ G H C N GS+ C C G+R DG +CED++EC ++ C
Sbjct: 400 VNECQRYPGRLCGH---KCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQE- 453
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT---LCENGHCSNTPGG 547
CAN GS++C C GY+ L V V +C DIDECA PT +C + C N PG
Sbjct: 454 -CANVYGSYQCYCRRGYQ-----LSDVDGV-TCEDIDECAL-PTGGHIC-SYRCINIPGS 504
Query: 548 YECDC-DVGFTRAADGRSC 565
++C C G+ A +GR+C
Sbjct: 505 FQCSCPSSGYRLAPNGRNC 523
Score = 130 bits (313), Expect = 2e-29
Identities = 87/248 (35%), Positives = 118/248 (47%), Gaps = 37/248 (14%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
D C GG PC QCR+T C+C G + G +C+D++EC
Sbjct: 178 DRCRGGG-PCKQ-QCRDTGDEVVCSCFVGYQLLSDGV--SCEDVNEC------------- 220
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCD 444
+ S ++ E SC NT+GSF CQ C GY + + +C D DECE G +
Sbjct: 221 -ITGSHSCRLGE-----SCINTVGSFRCQRDSSCGTGYELTEDN--SCKDIDECESGIHN 272
Query: 445 CHPAADCINLPGSFQCR----CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSF 499
C P C N GSF+CR C+ G+ D C D++ECL+ + C TC NT+GS+
Sbjct: 273 CLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSY 332
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTR 558
C + G GY L CVD+DECA C GH C N+PG + C+C G+
Sbjct: 333 TCQKNVPNCGRGYHLNEEGT--RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 559 AADGRSCL 566
R C+
Sbjct: 391 DGISRMCV 398
>AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D
precursor protein.
Length = 703
Score = 222 bits (542), Expect = 3e-57
Identities = 141/410 (34%), Positives = 188/410 (45%), Gaps = 60/410 (14%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCE----CG 230
C +T C C GY+ C D++EC CR G C+NT GSFRC+ CG
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG 249
Query: 231 HGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQC----VCDEGYAQSTVKSHXX 285
G EL D SCKDIDEC C + C+N +G+++C C G+ Q + +
Sbjct: 250 TGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL-GNCI 307
Query: 286 XXXXXXXXXXRCQ--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPC 338
C H+C+NT GSY C C G+HL +G C D+DECA A PC
Sbjct: 308 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Query: 339 GGG-QCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
G G +C N+ GS+ C C G G C D++EC
Sbjct: 368 GKGHRCVNSPGSFRCECKTGYYFD--GISRMCVDVNECQRYPG----------------- 408
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
LCG C NT+GS++C C G+ + + G +C D +EC C + +C N+ GS
Sbjct: 409 --RLCGH-KCENTLGSYLCSCSVGFRLSVD-GRSCEDINECSSSPC----SQECANVYGS 460
Query: 458 FQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+QC CR G++ DG TCED+DEC GG C N GSF+C C + G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS------GY 514
Query: 515 RTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYEC---DCDVGFTRAA 560
R +C DIDEC C N C N G + C +C + R+A
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSA 564
Score = 217 bits (531), Expect = 7e-56
Identities = 153/432 (35%), Positives = 194/432 (44%), Gaps = 59/432 (13%)
Query: 133 RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH----C 187
+CR+ C CF GY+ S +C DVNEC C G+ C NT GSF C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC----ECGHGMELAPDRL-S 241
GY+ + C DIDEC C C NT GSFRC +C G D L +
Sbjct: 249 GTGYELTE-DNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG--FIQDALGN 305
Query: 242 CKDIDECSITSGICSNG-ACENQMGTYQCV-----CDEGYAQSTVKSHXXXXXXXXXXXX 295
C DI+EC S C G C N G+Y C C GY + +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 296 RC--QHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H CVN+PGS+ C C+ G++ R C D++EC G +C NT+GSY C+
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C+ G S G +C+DI+EC S P C + C N GS
Sbjct: 426 CSVGFRLSVDGR--SCEDINEC-----------------SSSP-----C-SQECANVYGS 460
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDGWR--GDG 470
+ C C GY + G C D DEC L T + CIN+PGSFQC C G+R +G
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG 520
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLR-----TVCCVYS 522
C+D+DEC+T C TC N G+FRCL C Y+ L+ TV C+ S
Sbjct: 521 RNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSAATLQQEKTDTVRCIKS 580
Query: 523 CVDID-ECANDP 533
C D C DP
Sbjct: 581 CRPNDVTCVFDP 592
Score = 206 bits (503), Expect = 2e-52
Identities = 141/402 (35%), Positives = 180/402 (44%), Gaps = 56/402 (13%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCD----CFPGYEKDSKNHTCVDVNECEI-VDGVC 171
+VNEC C G C N +G F C C GYE N +C D++ECE +
Sbjct: 216 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCL 274
Query: 172 GDGDCHNTEGSFTCH----CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR 226
D C NT GSF C C+ G+ D C+DI+EC A C G C+NT GS+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 227 CE-----CGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTV 280
C+ CG G L + C D+DEC+ + C G C N G+++C C GY +
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 281 KSHXXXXXXXXXXXXR-CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
R C H C NT GSY C+C G+ L DGRSC DI+EC+ PC
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSS--PCS 451
Query: 340 GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIP 399
+C N GSY C C G S TC+DIDECA P
Sbjct: 452 Q-ECANVYGSYQCYCRRGYQLSDVDGV-TCEDIDECA------------------LPTGG 491
Query: 400 ELCGAGSCHNTIGSFVCQCP-DGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
+C + C N GSF C CP GY + P G C D DEC G +C C N+ G+F
Sbjct: 492 HIC-SYRCINIPGSFQCSCPSSGYRLAP-NGRNCQDIDECVTGIHNCSINETCFNIQGAF 549
Query: 459 QC---RCRDGWRGDGATCE----DVDECLTNNGGCHPR-ATC 492
+C C + +R AT + D C+ + C P TC
Sbjct: 550 RCLAFECPENYRRSAATLQQEKTDTVRCIKS---CRPNDVTC 588
Score = 181 bits (441), Expect = 5e-45
Identities = 100/274 (36%), Positives = 134/274 (48%), Gaps = 18/274 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC-----DCFPGYEKDSKNHTCVDVNECEIVDGV 170
+++NEC + C G C N G +TC +C GY + + CVDV+EC
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 171 CGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC 229
CG G C N+ GSF C C+ GY D S++CVD++EC G +C NT GS+ C C
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSC 426
Query: 230 GHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKS---HXXX 286
G L+ D SC+DI+ECS S CS C N G+YQC C GY S V
Sbjct: 427 SVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDID 483
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDECAGGARPCGGGQ-CR 344
C + C+N PGS+ C+C G+ L +GR+C+DIDEC G C + C
Sbjct: 484 ECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF 543
Query: 345 NTVGSYTC---TCTDGLVPSAAGAKPTCQDIDEC 375
N G++ C C + SAA + D C
Sbjct: 544 NIQGAFRCLAFECPENYRRSAATLQQEKTDTVRC 577
Score = 155 bits (377), Expect = 3e-37
Identities = 129/379 (34%), Positives = 175/379 (46%), Gaps = 61/379 (16%)
Query: 213 CRGG-----RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGT 266
CRGG +C +T C C G +L D +SC+D++EC S C G +C N +G+
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 239
Query: 267 YQC----VCDEGYAQSTVKSHXXXXXXXXXXXXRC--QHSCVNTPGSYHC----TCREGW 316
++C C GY + T + C C NT GS+ C C+ G+
Sbjct: 240 FRCQRDSSCGTGY-ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF 298
Query: 317 HLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
A G +C DI+EC + PC G C NT GSYTC VP+ ++ C
Sbjct: 299 IQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN---VPNCGRGYHLNEEGTRC 354
Query: 376 ADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTIGSFVCQCPDGYSVKPEQGPACTD 434
D VDE +P CG G C N+ GSF C+C GY C D
Sbjct: 355 VD---------VDECAPPAEP-----CGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVD 399
Query: 435 DDECEL--GTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRA 490
+EC+ G H C N GS+ C C G+R DG +CED++EC ++ C
Sbjct: 400 VNECQRYPGRLCGH---KCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQE- 453
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT---LCENGHCSNTPGG 547
CAN GS++C C GY+ L V V +C DIDECA PT +C + C N PG
Sbjct: 454 -CANVYGSYQCYCRRGYQ-----LSDVDGV-TCEDIDECAL-PTGGHIC-SYRCINIPGS 504
Query: 548 YECDC-DVGFTRAADGRSC 565
++C C G+ A +GR+C
Sbjct: 505 FQCSCPSSGYRLAPNGRNC 523
Score = 130 bits (313), Expect = 2e-29
Identities = 87/248 (35%), Positives = 118/248 (47%), Gaps = 37/248 (14%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
D C GG PC QCR+T C+C G + G +C+D++EC
Sbjct: 178 DRCRGGG-PCKQ-QCRDTGDEVVCSCFVGYQLLSDGV--SCEDVNEC------------- 220
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCD 444
+ S ++ E SC NT+GSF CQ C GY + + +C D DECE G +
Sbjct: 221 -ITGSHSCRLGE-----SCINTVGSFRCQRDSSCGTGYELTEDN--SCKDIDECESGIHN 272
Query: 445 CHPAADCINLPGSFQCR----CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSF 499
C P C N GSF+CR C+ G+ D C D++ECL+ + C TC NT+GS+
Sbjct: 273 CLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSY 332
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTR 558
C + G GY L CVD+DECA C GH C N+PG + C+C G+
Sbjct: 333 TCQKNVPNCGRGYHLNEEGT--RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 559 AADGRSCL 566
R C+
Sbjct: 391 DGISRMCV 398
>AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 218 bits (533), Expect = 4e-56
Identities = 155/430 (36%), Positives = 197/430 (45%), Gaps = 65/430 (15%)
Query: 134 CRNLLGGFTCD-----CFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCH- 186
C N LG F C C GY ++ + CV NEC C G+ C NT GSF C+
Sbjct: 736 CVNTLGSFYCVNHTVLCADGYILNA-HRKCVGKNECVTDLHTCSRGEHCVNTLGSFHCYK 794
Query: 187 ---CRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRCE----CGHGMELAPD 238
C PGY D C D+DECA C+ G C NT GSF C+ C G P+
Sbjct: 795 ALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE 852
Query: 239 RLSCKDIDECSITSGICSNG-ACENQMGTYQC-----VCDEGYAQSTVKSHXXXXXXXXX 292
+C DI+EC+ S C G +C N +G+Y C +C GY S +
Sbjct: 853 G-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECET 911
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDEC-AGGARPCGGGQCRNTVGS 349
RC C N PGSY C C+ G+ A GR C D++EC A R C C NT+GS
Sbjct: 912 GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGS 970
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
Y C+C G + +A G + C+D++EC E Q+ C C N
Sbjct: 971 YRCSCASGFLLAADGKR--CEDVNEC-------------EAQR---------CSQ-ECAN 1005
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD-GWR- 467
GS+ C C GY + E G CTD DEC G C+N+PGS+QC C + G+
Sbjct: 1006 IYGSYQCYCRQGYQLA-EDGHTCTDIDECAQGA-GILCTFRCLNVPGSYQCACPEQGYTM 1063
Query: 468 -GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLRTVCCVYSC 523
+G +C+DVDEC C TC N GSFRCL C Y +T C +C
Sbjct: 1064 TANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVS---KTKCERTTC 1120
Query: 524 VDIDECANDP 533
D EC N P
Sbjct: 1121 HDFLECQNSP 1130
Score = 215 bits (524), Expect = 5e-55
Identities = 151/445 (33%), Positives = 197/445 (44%), Gaps = 67/445 (15%)
Query: 134 CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTC--H---C 187
C + G C CFPGY + +C D +EC + C C NT GSF C H C
Sbjct: 693 CSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLC 752
Query: 188 RPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRC----ECGHGMELAPDRLSC 242
GY + K CV +EC + C RG CVNT GSF C C G L C
Sbjct: 753 ADGYILNAHRK-CVGKNECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG--EC 809
Query: 243 KDIDECSITSGICSNG-ACENQMGTYQCV----CDEGYAQSTVKSHXXXXXXXXXXXXRC 297
+D+DEC++ + C G C+N G++ C C +G+ Q + + C
Sbjct: 810 EDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDP-EGNCVDINECTSLSEPC 868
Query: 298 Q--HSCVNTPGSYHC-----TCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGS 349
+ SC+NT GSY C C G+H DG C D++EC G CG GQ C N GS
Sbjct: 869 RPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGS 928
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
Y C C G A G C D++EC P LC +C N
Sbjct: 929 YRCDCKAGFQRDAFGR--GCIDVNEC-----------------WASP--GRLC-QHTCEN 966
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-- 467
T+GS+ C C G+ + + G C D +ECE C + +C N+ GS+QC CR G++
Sbjct: 967 TLGSYRCSCASGFLLAAD-GKRCEDVNECEAQRC----SQECANIYGSYQCYCRQGYQLA 1021
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC-DTGYKGDGYGLRTVCCVYSCVDI 526
DG TC D+DEC G C N GS++C C + GY G SC D+
Sbjct: 1022 EDGHTCTDIDEC-AQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG-------RSCKDV 1073
Query: 527 DECANDPTLCENGH-CSNTPGGYEC 550
DECA C C N G + C
Sbjct: 1074 DECALGTHNCSEAETCHNIQGSFRC 1098
Score = 205 bits (500), Expect = 4e-52
Identities = 132/360 (36%), Positives = 165/360 (45%), Gaps = 48/360 (13%)
Query: 120 NECAAFPGLCGHGR-CRNLLGGFTC----DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
NEC C G C N LG F C C PGY K+ C DV+EC + C G
Sbjct: 768 NECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL--KDGECEDVDECAMGTHTCQPG 825
Query: 175 D-CHNTEGSFTCH----CRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRCE 228
C NT+GSF C C G+ D CVDI+EC CR G C+NT GS+ C+
Sbjct: 826 FLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGSYTCQ 884
Query: 229 -----CGHGMELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTVKS 282
C G + D C D++EC C G C N G+Y+C C G+ +
Sbjct: 885 RNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGR 944
Query: 283 HXXXXXXXXXXXXR-CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGG 341
R CQH+C NT GSY C+C G+ L ADG+ C D++EC A+ C
Sbjct: 945 GCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE--AQRCSQ- 1001
Query: 342 QCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPEL 401
+C N GSY C C G + G TC DIDECA L
Sbjct: 1002 ECANIYGSYQCYCRQGYQLAEDGH--TCTDIDECAQGAGI-------------------L 1040
Query: 402 CGAGSCHNTIGSFVCQCPD-GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC 460
C C N GS+ C CP+ GY++ G +C D DEC LGT +C A C N+ GSF+C
Sbjct: 1041 C-TFRCLNVPGSYQCACPEQGYTMTAN-GRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
Score = 199 bits (486), Expect = 2e-50
Identities = 155/475 (32%), Positives = 209/475 (44%), Gaps = 82/475 (17%)
Query: 120 NECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
+EC PG LC H C N +G + C CFPG+ TC +G
Sbjct: 606 DECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRP------------EGHPPQ 652
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDE---CADNDALCRGGRCVNTAGSFRCECGHGMEL 235
E + + + I + + + C DN C+ C GS C C G +
Sbjct: 653 PEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGP-CK-QVCSTVGGSAICSCFPGYAI 710
Query: 236 APDRLSCKDIDECSITSGICSNGA-CENQMGTYQCV-----CDEGYAQSTVKS--HXXXX 287
D +SC+D DEC + + CS C N +G++ CV C +GY + +
Sbjct: 711 MADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVGKNEC 770
Query: 288 XXXXXXXXRCQHSCVNTPGSYHC----TCREGWHLRADGRSCRDIDECAGGARPCGGG-Q 342
R +H CVNT GS+HC TC G+ L+ DG C D+DECA G C G
Sbjct: 771 VTDLHTCSRGEH-CVNTLGSFHCYKALTCEPGYALK-DG-ECEDVDECAMGTHTCQPGFL 827
Query: 343 CRNTVGSYTC----TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQI 398
C+NT GS+ C C DG + G C DI+EC L
Sbjct: 828 CQNTKGSFYCQARQRCMDGFLQDPEG---NCVDINECTSL-------------------- 864
Query: 399 PELCGAG-SCHNTIGSFVCQ-----CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCI 452
E C G SC NT+GS+ CQ C GY + G C D +ECE G C C
Sbjct: 865 SEPCRPGFSCINTVGSYTCQRNPLICARGYHAS-DDGAKCVDVNECETGVHRCGEGQVCH 923
Query: 453 NLPGSFQCRCRDGWRGD--GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
NLPGS++C C+ G++ D G C DV+EC + G + TC NT GS+RC C +G+
Sbjct: 924 NLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL-CQHTCENTLGSYRCSCASGFLLA 982
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G R C D++EC + C C+N G Y+C C G+ A DG +C
Sbjct: 983 ADGKR-------CEDVNEC--EAQRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTC 1027
Score = 186 bits (453), Expect = 2e-46
Identities = 147/437 (33%), Positives = 185/437 (42%), Gaps = 74/437 (16%)
Query: 156 HTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC-R 214
+TC D C+ V C GS C C PGY C D DEC C R
Sbjct: 681 NTCKDNGPCKQV--------CSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSR 732
Query: 215 GGRCVNTAGSFRCE-----CGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQ 268
CVNT GSF C C G L R C +EC CS G C N +G++
Sbjct: 733 RQFCVNTLGSFYCVNHTVLCADGYILNAHR-KCVGKNECVTDLHTCSRGEHCVNTLGSFH 791
Query: 269 C----VCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCT----CREGWHLRA 320
C C+ GYA + + C NT GS++C C +G+
Sbjct: 792 CYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDP 851
Query: 321 DGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCT-----CTDGLVPSAAGAKPTCQDIDE 374
+G +C DI+EC + PC G C NTVGSYTC C G S GAK C D++E
Sbjct: 852 EG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAK--CVDVNE 908
Query: 375 CADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACT 433
C + CG G CHN GS+ C C G+ + G C
Sbjct: 909 CETGVHR--------------------CGEGQVCHNLPGSYRCDCKAGFQ-RDAFGRGCI 947
Query: 434 DDDEC--ELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPR 489
D +EC G H C N GS++C C G+ DG CEDV+EC C
Sbjct: 948 DVNECWASPGRLCQHT---CENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQE 1002
Query: 490 ATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYE 549
CAN GS++C C GY+ G ++C DIDECA + C N PG Y+
Sbjct: 1003 --CANIYGSYQCYCRQGYQLAEDG-------HTCTDIDECAQGAGILCTFRCLNVPGSYQ 1053
Query: 550 CDC-DVGFTRAADGRSC 565
C C + G+T A+GRSC
Sbjct: 1054 CACPEQGYTMTANGRSC 1070
Score = 185 bits (450), Expect = 4e-46
Identities = 121/354 (34%), Positives = 159/354 (44%), Gaps = 50/354 (14%)
Query: 118 EVNECAAFPGLCGHG-RCRNLLGGFTCD----CFPGYEKDSKNHTCVDVNECEIVDGVCG 172
+V+ECA C G C+N G F C C G+ +D + + CVD+NEC + C
Sbjct: 811 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCR 869
Query: 173 DG-DCHNTEGSFTCH-----CRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSF 225
G C NT GS+TC C GY A D CVD++EC C G+ C N GS+
Sbjct: 870 PGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSY 929
Query: 226 RCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXX 285
RC+C G + C D++EC + G CEN +G+Y+C C G+ +
Sbjct: 930 RCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAA--DGKR 987
Query: 286 XXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN 345
RC C N GSY C CR+G+ L DG +C DIDECA GA +C N
Sbjct: 988 CEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLN 1047
Query: 346 TVGSYTCTCTD-GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA 404
GSY C C + G +A G +C+D+DECA + T A
Sbjct: 1048 VPGSYQCACPEQGYTMTANGR--SCKDVDECA--LGT-----------------HNCSEA 1086
Query: 405 GSCHNTIGSFVC---QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP 455
+CHN GSF C +CP Y +CE T CH +C N P
Sbjct: 1087 ETCHNIQGSFRCLRFECPPNY--------VQVSKTKCERTT--CHDFLECQNSP 1130
Score = 166 bits (404), Expect = 2e-40
Identities = 133/427 (31%), Positives = 174/427 (40%), Gaps = 63/427 (14%)
Query: 160 DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCV 219
D +EC ++ G C NT GS+ C C PG+ D + C +A
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA--- 660
Query: 220 NTAGSFRCECGHGMEL-APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYA-- 276
F + + L P +CKD +G C C G+ C C GYA
Sbjct: 661 -LKSEFSQVASNTIPLPLPQPNTCKD-------NGPCKQ-VCSTVGGSAICSCFPGYAIM 711
Query: 277 QSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCT-----CREGWHLRADGRSCRDIDEC 331
V + CVNT GS++C C +G+ L A R C +EC
Sbjct: 712 ADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVGKNEC 770
Query: 332 AGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
C G+ C NT+GS+ C P A C+D+DECA M
Sbjct: 771 VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECA--------MGTHTC 822
Query: 391 QKSVDPQIPELCGAGSCHNTIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCDCH 446
Q C NT GSF CQ C DG+ PE C D +EC + C
Sbjct: 823 QPGF-----------LCQNTKGSFYCQARQRCMDGFLQDPEGN--CVDINECTSLSEPCR 869
Query: 447 PAADCINLPGSFQCR-----CRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTDGSF 499
P CIN GS+ C+ C G+ DGA C DV+EC T C C N GS+
Sbjct: 870 PGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSY 929
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDEC-ANDPTLCENGHCSNTPGGYECDCDVGFTR 558
RC C G++ D +G C+D++EC A+ LC++ C NT G Y C C GF
Sbjct: 930 RCDCKAGFQRDAFG-------RGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLL 981
Query: 559 AADGRSC 565
AADG+ C
Sbjct: 982 AADGKRC 988
Score = 159 bits (387), Expect = 2e-38
Identities = 105/292 (35%), Positives = 131/292 (44%), Gaps = 55/292 (18%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C+ C GS C+C G+ + ADG SC D DEC GA C Q C NT+GS+ C
Sbjct: 689 CKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNH 748
Query: 354 ---CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHN 409
C DG + A C +EC + T C G C N
Sbjct: 749 TVLCADGYI---LNAHRKCVGKNECVTDLHT--------------------CSRGEHCVN 785
Query: 410 TIGSFVCQ----CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC----R 461
T+GSF C C GY++K + C D DEC +GT C P C N GSF C R
Sbjct: 786 TLGSFHCYKALTCEPGYALKDGE---CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR 842
Query: 462 CRDGWRGDG-ATCEDVDECLTNNGGCHPRATCANTDGSFRC-----LCDTGYKGDGYGLR 515
C DG+ D C D++EC + + C P +C NT GS+ C +C GY G +
Sbjct: 843 CMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAK 902
Query: 516 TVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTRAADGRSCL 566
CVD++EC C G C N PG Y CDC GF R A GR C+
Sbjct: 903 -------CVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 947
Score = 137 bits (332), Expect = 8e-32
Identities = 70/198 (35%), Positives = 96/198 (48%), Gaps = 7/198 (3%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++VNEC CG G+ C NL G + CDC G+++D+ C+DVNEC G
Sbjct: 904 VDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT 963
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C NT GS+ C C G+ K C D++EC +A C N GS++C C G +L
Sbjct: 964 CENTLGSYRCSCASGFLLAADGKRCEDVNEC---EAQRCSQECANIYGSYQCYCRQGYQL 1020
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVC-DEGYAQSTVKSHXXXXXXXXXXX 294
A D +C DIDEC+ +GI C N G+YQC C ++GY +
Sbjct: 1021 AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGT 1080
Query: 295 XRCQ--HSCVNTPGSYHC 310
C +C N GS+ C
Sbjct: 1081 HNCSEAETCHNIQGSFRC 1098
Score = 129 bits (311), Expect = 3e-29
Identities = 65/167 (38%), Positives = 89/167 (53%), Gaps = 10/167 (5%)
Query: 117 MEVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++VNEC A PG LC H C N LG + C C G+ + C DVNECE C +
Sbjct: 947 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQ-E 1002
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHGME 234
C N GS+ C+CR GY+ + C DIDECA + RC+N GS++C C G
Sbjct: 1003 CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYT 1062
Query: 235 LAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCV---CDEGYAQ 277
+ + SCKD+DEC++ + CS C N G+++C+ C Y Q
Sbjct: 1063 MTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQ 1109
Score = 126 bits (304), Expect = 2e-28
Identities = 94/304 (30%), Positives = 122/304 (40%), Gaps = 49/304 (16%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
CQH C+NT GSYHC C G+ L+ DGR+CR G P + S
Sbjct: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCR-----PEGHPPQPEAPQEPALKSEFSQVAS 670
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDE-------LQKSVDPQIPELCGAGS--- 406
+P TC+D C + ST+ ++ + V + + C G+
Sbjct: 671 NTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDC 730
Query: 407 -----CHNTIGSFVC-----QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPG 456
C NT+GSF C C DGY + + C +EC C C+N G
Sbjct: 731 SRRQFCVNTLGSFYCVNHTVLCADGYILNAHR--KCVGKNECVTDLHTCSRGEHCVNTLG 788
Query: 457 SFQC----RCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRC----LCDTGYK 508
SF C C G+ CEDVDEC C P C NT GSF C C G+
Sbjct: 789 SFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFL 848
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECD-----CDVGFTRAADG 562
D G +CVDI+EC + C G C NT G Y C C G+ + DG
Sbjct: 849 QDPEG--------NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 900
Query: 563 RSCL 566
C+
Sbjct: 901 AKCV 904
>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
protein.
Length = 1640
Score = 202 bits (492), Expect = 3e-51
Identities = 119/366 (32%), Positives = 166/366 (45%), Gaps = 34/366 (9%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
C G+ + C+ EC G+C G + CHC PG++ + D+D
Sbjct: 185 CCRGWMQQPDEEGCLSA-ECSA--GLCFHGGRCVPGSAQPCHCPPGFQGP---RCQYDVD 238
Query: 205 ECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQM 264
EC ++ C+ RCVNT GS+ CEC G L D +C I+ C++ +G C + + +
Sbjct: 239 ECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTI 297
Query: 265 GTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRS 324
++C C G+ H C H C G C C G+ L ADG++
Sbjct: 298 TRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKA 357
Query: 325 CRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIM 384
C D+DECA G C G C NT GS+ C C G A G + C I+ M
Sbjct: 358 CEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQ--CYRIE----------M 404
Query: 385 MSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCD 444
V+ + + C G H + G +C CP GY + +Q C D D+C C
Sbjct: 405 EIVNSCEANNGG-----CSHGCSHTSAGP-LCTCPRGYELDTDQR-TCIDVDDCADSPC- 456
Query: 445 CHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
C C N PG ++C C G+R DG CEDVDEC ++ GGC C N GSF+C
Sbjct: 457 CQQV--CTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHH--CTNLAGSFQCS 512
Query: 503 CDTGYK 508
C+ GY+
Sbjct: 513 CEAGYR 518
Score = 180 bits (437), Expect = 2e-44
Identities = 92/266 (34%), Positives = 128/266 (48%), Gaps = 12/266 (4%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
Q +V+EC G C H RC N G + C+C PG+ + + TC+ +N C + +G C
Sbjct: 234 QYDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHC 292
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
T C CRPG++ + + CV CA+ + C RC G RCEC G +L
Sbjct: 293 VQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCM-HRCQVVRGLARCECHVGYQL 351
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-----AQSTVKSHXXXXXXX 290
A D +C+D+DEC+ C++G C N G+++CVC GY + +
Sbjct: 352 AADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSC 410
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSY 350
C H C +T CTC G+ L D R+C D+D+CA PC C N G Y
Sbjct: 411 EANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS--PCCQQVCTNNPGGY 468
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECA 376
C C G SA G C+D+DECA
Sbjct: 469 ECGCYAGYRLSADGC--GCEDVDECA 492
Score = 162 bits (393), Expect = 3e-39
Identities = 121/408 (29%), Positives = 160/408 (39%), Gaps = 46/408 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+ +N CA G C H + + C C PG++ CV + C +G C C
Sbjct: 276 LAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHR-C 334
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
G C C GY+ K C D+DECA A C G C+NT GSF+C C G EL
Sbjct: 335 QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELG 393
Query: 237 PD-----RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
D R+ + ++ C +G CS+G G C C GY T
Sbjct: 394 ADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPL-CTCPRGYELDT-DQRTCIDVDDC 451
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
CQ C N PG Y C C G+ L ADG C D+DECA C C N GS+
Sbjct: 452 ADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGSFQ 510
Query: 352 CTCTDG--LVPSAAGAKPTCQ---DIDECADLISTIIMMSV--DELQK-------SVDPQ 397
C+C G L G P + D+D + + ++V DEL + D +
Sbjct: 511 CSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEE 570
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
EL G H FVC D + +C L DC C L G
Sbjct: 571 EAELRGE---HTLTEKFVC-LDDSFG------------HDCSLTCDDCRNGGTC--LLGL 612
Query: 458 FQCRCRDGWRG--DGATC--EDVDECLTNNGGCHPRATCANTDGSFRC 501
C C +GW G TC + + + + C TC + G+ RC
Sbjct: 613 DGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC 660
Score = 153 bits (371), Expect = 2e-36
Identities = 110/344 (31%), Positives = 142/344 (41%), Gaps = 50/344 (14%)
Query: 229 CGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXX 288
C G PD C ECS +G+C +G C C G+ +
Sbjct: 185 CCRGWMQQPDEEGCLSA-ECS--AGLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECR 241
Query: 289 XXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVG 348
CQH CVNTPGSY C C+ G+ L D R+C I+ CA G C + T+
Sbjct: 242 THNGG---CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTIT 298
Query: 349 SYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCH 408
+ C C G G C CA+ + + C
Sbjct: 299 RHRCQCRPGFQLQEDGRH--CVRRSPCANRNGSCMHR---------------------CQ 335
Query: 409 NTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR- 467
G C+C GY + + G AC D DEC G C A C+N GSF+C C G+
Sbjct: 336 VVRGLARCECHVGYQLAAD-GKACEDVDECAAGLAQC--AHGCLNTQGSFKCVCHAGYEL 392
Query: 468 -GDGATC-----EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
DG C E V+ C NNGGC C++T C C GY+ D RT
Sbjct: 393 GADGRQCYRIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDT-DQRT----- 444
Query: 522 SCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C+D+D+CA+ P C C+N PGGYEC C G+ +ADG C
Sbjct: 445 -CIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGC 485
Score = 147 bits (357), Expect = 8e-35
Identities = 118/397 (29%), Positives = 164/397 (41%), Gaps = 53/397 (13%)
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMEL 235
+ TE C G+ + C+ EC+ LC GGRCV + C C G +
Sbjct: 175 YTTEARTVLRCCRGWMQQPDEEGCLSA-ECSAG--LCFHGGRCVPGSAQ-PCHCPPGFQ- 229
Query: 236 APDRLSCK-DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
P C+ D+DEC +G C + C N G+Y C C G+ T
Sbjct: 230 GP---RCQYDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGN 285
Query: 295 XRCQHSCVNTPGSYH-CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
CQH CV + H C CR G+ L+ DGR C CA C +C+ G C
Sbjct: 286 GGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCE 344
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G +A G C+D+DECA ++ C G C NT GS
Sbjct: 345 CHVGYQLAADGK--ACEDVDECAAGLAQ--------------------CAHG-CLNTQGS 381
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAA---DCINLPGSFQCRCRDGWR--G 468
F C C GY + + G C + + +C+ + C + C C G+
Sbjct: 382 FKCVCHAGYELGAD-GRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDT 440
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
D TC DVD+C ++ C + C N G + C C GY+ G C C D+DE
Sbjct: 441 DQRTCIDVDDC-ADSPCC--QQVCTNNPGGYECGCYAGYRLSADG-----C--GCEDVDE 490
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
CA+ CE+ HC+N G ++C C+ G+ D R C
Sbjct: 491 CASSRGGCEH-HCTNLAGSFQCSCEAGYRLHEDRRGC 526
Score = 92.3 bits (219), Expect = 4e-18
Identities = 82/279 (29%), Positives = 107/279 (38%), Gaps = 49/279 (17%)
Query: 297 CQHSCVNTPGSYH-CTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCTC 354
C H PGS C C G+ G C+ D+DEC C +C NT GSY C C
Sbjct: 208 CFHGGRCVPGSAQPCHCPPGFQ----GPRCQYDVDECRTHNGGCQH-RCVNTPGSYLCEC 262
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN----- 409
G TC I+ CA G G C +
Sbjct: 263 KPGFRLHTDSR--TCLAINSCA-------------------------LGNGGCQHHCVQL 295
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-- 467
TI CQC G+ ++ E G C C C + G +C C G++
Sbjct: 296 TITRHRCQCRPGFQLQ-EDGRHCVRRSPCANRNGSCMHRCQVVR--GLARCECHVGYQLA 352
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
DG CEDVDEC C C NT GSF+C+C GY+ G + C ++
Sbjct: 353 ADGKACEDVDECAAGLAQC--AHGCLNTQGSFKCVCHAGYELGADGRQ--CYRIEMEIVN 408
Query: 528 ECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C + C +G CS+T G C C G+ D R+C+
Sbjct: 409 SCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCI 446
Score = 78.2 bits (184), Expect = 7e-14
Identities = 58/167 (34%), Positives = 79/167 (47%), Gaps = 21/167 (12%)
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQ-CR 461
G + T V +C G+ +P++ C EC G C C+ PGS Q C
Sbjct: 170 GYRQVYTTEARTVLRCCRGWMQQPDE-EGCLSA-ECSAGLC--FHGGRCV--PGSAQPCH 223
Query: 462 CRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
C G++G C+ DVDEC T+NGGC R C NT GS+ C C G++ L T
Sbjct: 224 CPPGFQGP--RCQYDVDECRTHNGGCQHR--CVNTPGSYLCECKPGFR-----LHTDS-- 272
Query: 521 YSCVDIDECANDPTLCENGHCSN-TPGGYECDCDVGFTRAADGRSCL 566
+C+ I+ CA C++ HC T + C C GF DGR C+
Sbjct: 273 RTCLAINSCALGNGGCQH-HCVQLTITRHRCQCRPGFQLQEDGRHCV 318
Score = 67.7 bits (158), Expect = 1e-10
Identities = 96/409 (23%), Positives = 137/409 (33%), Gaps = 56/409 (13%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICV--DIDECADNDALCRGGRCVNTAGSFRCECGH-G 232
C + G C G++ +D + C + C G C G RC G G
Sbjct: 782 CDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTG 841
Query: 233 MELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ D + C C + A C+ + G C+C G+ S +
Sbjct: 842 EDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGP 899
Query: 292 XXXXRCQHSCVNT----PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTV 347
RC SC N P + HC+C GW G SC+ + C C +
Sbjct: 900 SCQTRC--SCANDGHCHPATGHCSCAPGW----TGFSCQRACDTGHWGPDC-SHPCNCSA 952
Query: 348 GSYTCTCTDGLVPSAAG-AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC---G 403
G +C GL AG P C+ +C Q P +LC
Sbjct: 953 GHGSCDAISGLCLCEAGYVGPRCE--QQCP--------------QGHFGPGCEQLCQCQH 996
Query: 404 AGSCHNTIGSFVCQCPDGY--SVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR 461
+C + G+ C CP G+ + PA +C C+C A C + GS C
Sbjct: 997 GAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCR-SACNCTAGAACDAVNGS--CL 1051
Query: 462 CRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDG----SFRCLCDTGYKGDGYGLRTV 517
C G R G C + T C C N +C C G+ G
Sbjct: 1052 CPAGRR--GPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACP 1109
Query: 518 CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+Y D C + LC+NG + G+ C C G+ A + CL
Sbjct: 1110 AGLYG----DNCRHS-CLCQNGGTCDPVSGH-CACPEGWAGLACEKECL 1152
Score = 67.7 bits (158), Expect = 1e-10
Identities = 111/427 (25%), Positives = 145/427 (33%), Gaps = 72/427 (16%)
Query: 171 CGDG-DCHNTEGSFTCHCRPGYKADDFSKIC---VDIDECADNDALCR-GGRCVNTAGSF 225
C +G C G CHC PG+ + C + D C + LC+ GG C +G
Sbjct: 1080 CFNGASCDPVHGQ--CHCAPGWMGPSCLQACPAGLYGDNCR-HSCLCQNGGTCDPVSG-- 1134
Query: 226 RCECGHGMELAPDRLSC--KDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKS 282
C C G C +D+ SG C NG C+ G +C+C G+ +S
Sbjct: 1135 HCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQS 1192
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGSYH----CTCREGWHLRADGRSCRDIDECAGGARPC 338
RC SC +H C C G+ G C C
Sbjct: 1193 PCLRGWFGEACAQRC--SCPPAAACHHVTGACRCPPGF----TGSGCEQACPPGSFGEDC 1246
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAAGAK-PTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
C+ + C G AAG P+CQ C P
Sbjct: 1247 AQ-MCQCPGENPACHPATGTCSCAAGYHGPSCQQ--RCPP--------------GRYGPG 1289
Query: 398 IPELCGA---GSCHNTIGSFVCQCPDGYS------VKPEQ--GPACTDDDECELGTCDCH 446
+LCG GSC G+ C+CP G+ P+ GP CT C G C
Sbjct: 1290 CEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAA-CD 1346
Query: 447 PAAD-CINLPGSFQCRCRDGWRGD--GATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
P C+ PG RC G + G CE C N G CH ++GS C C
Sbjct: 1347 PVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSC-RNGGLCHA------SNGS--CSC 1397
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECA-NDPTLCE--NGHCSNTPGGYECDCDVGFTRAA 560
G+ G L Y EC+ ++ + CE G C PG Y C+
Sbjct: 1398 GLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGF 1457
Query: 561 DGRSCLG 567
G C G
Sbjct: 1458 HGAGCQG 1464
Score = 58.4 bits (135), Expect = 6e-08
Identities = 118/469 (25%), Positives = 153/469 (32%), Gaps = 78/469 (16%)
Query: 130 GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVN---ECEIVDGVCGDGDCHNTEGSFTCH 186
GHG C + G C C GY C + CE + C + G+ C
Sbjct: 953 GHGSCDAISG--LCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGA--CT 1008
Query: 187 CRPGYKADDFSKICVDIDECADNDALCR---GGRCVNTAGSFRCECGHGMELAPDRLSCK 243
C G++ C D + C G C GS C G +
Sbjct: 1009 CPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAH 1068
Query: 244 DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
+ C NGA C+ G QC C G+ + C+HSC+
Sbjct: 1069 TYGHNCSQACACFNGASCDPVHG--QCHCAPGWMGPSCLQ----ACPAGLYGDNCRHSCL 1122
Query: 303 NTPG------SYHCTCREGWHLRADGRSCRDIDECAGGARPCG---GGQCRNTVGSYTCT 353
G S HC C EGW A + C D AG G GG C G C
Sbjct: 1123 CQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCL 1180
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G D+C + S P A +CH+ G+
Sbjct: 1181 CPAGWTG------------DKCQSPCLRGWFGEACAQRCSCPP-------AAACHHVTGA 1221
Query: 414 FVCQCPDGYSVKP-EQG--PACTDDDECELGTCD-----CHPA-ADCINLPG----SFQC 460
C+CP G++ EQ P +D ++ C CHPA C G S Q
Sbjct: 1222 --CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQ 1279
Query: 461 RCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
RC G G G CE + CL NGG AT A C C TG+ G L
Sbjct: 1280 RCPPGRYGPG--CEQLCGCL--NGGSCDAATGA-------CRCPTGFLGTDCNLTCPQGR 1328
Query: 521 Y--SCVDIDECANDPTLCE--NGHCSNTPGGYECDCDVGFTRAADGRSC 565
+ +C + C C+ G C PG C+ G + G C
Sbjct: 1329 FGPNCTHVCGCGQG-AACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGC 1376
Score = 51.2 bits (117), Expect = 1e-05
Identities = 117/492 (23%), Positives = 159/492 (32%), Gaps = 69/492 (14%)
Query: 122 CAAFPGL-CG--HGRCRNLLG--GFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
CA F G C HG+C G G +C C G D+ H+C+ C+ G
Sbjct: 1078 CACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCL----CQ------NGG 1127
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDE---CADNDALCRGGRCVNTAGSFRCECGH 231
C G C C G+ K C+ D C + GG C G C G
Sbjct: 1128 TCDPVSGH--CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGW 1185
Query: 232 -GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
G + L + C+ AC + G C C G+ S +
Sbjct: 1186 TGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGA--CRCPPGFTGSGCEQACPPGSFG 1243
Query: 291 XXXXXRCQHSCVNT---PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG---GGQCR 344
CQ N P + C+C G+H + + C G + CG GG C
Sbjct: 1244 EDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCD 1303
Query: 345 NTVGSYTCTC----TDGLVPSAAGA-KPTCQDIDECA-----DLISTIIMMSVDELQKSV 394
G+ C TD + G P C + C D ++ +
Sbjct: 1304 AATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRC 1363
Query: 395 DPQIPE---------LCGA---GSCHNTIGSFVCQCPDGYSVKPEQ--GPACTDDDECEL 440
+ P+ C G CH + GS C C G++ + + P C L
Sbjct: 1364 ERGCPQNRFGVGCEHTCSCRNGGLCHASNGS--CSCGLGWTGRHCELACPPGRYGAACHL 1421
Query: 441 GTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATC---ANTDG 497
C CH + C P + CRC G+ G CE + GC C A D
Sbjct: 1422 -ECSCHNNSTCE--PATGTCRCGPGFYGQA--CEHPCPPGFHGAGCQGLCWCQHGAPCDP 1476
Query: 498 -SFRCLCDTGYKGD--GYGLRTVCCVYSCVDIDEC-ANDPTLCENGHCSNTPGGYECDCD 553
S RCLC G+ G G C +C P G C PG C+
Sbjct: 1477 ISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCN 1536
Query: 554 VGFTRAADGRSC 565
+ R G SC
Sbjct: 1537 LDCRRGQFGPSC 1548
Score = 49.6 bits (113), Expect = 3e-05
Identities = 99/387 (25%), Positives = 126/387 (32%), Gaps = 66/387 (17%)
Query: 134 CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC---GDGD-CHNTEGSFTCHCRP 189
C ++ G C C PG+ C + E +C G+ CH G TC C
Sbjct: 1215 CHHVTGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATG--TCSCAA 1270
Query: 190 GYKADDFSKICVDIDECADNDALC---RGGRCVNTAGSFRCECGHGMELAPD-RLSCKDI 245
GY + C + LC GG C G+ RC G L D L+C
Sbjct: 1271 GYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGF---LGTDCNLTCPQG 1327
Query: 246 ---DECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC- 301
C+ G AC+ GT C+C G A + C+H+C
Sbjct: 1328 RFGPNCTHVCGCGQGAACDPVTGT--CLCPPGRAGVRCERGCPQNRFGVG----CEHTCS 1381
Query: 302 VNTPGSYH-----CTCREGWHLR---------ADGRSCRDIDECAGGARPC--GGGQCRN 345
G H C+C GW R G +C C + C G CR
Sbjct: 1382 CRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNST-CEPATGTCRC 1440
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDEC-----ADLISTIIMMSVDELQKSVDPQI-P 399
G Y C P GA CQ + C D IS + + P
Sbjct: 1441 GPGFYGQACEHPCPPGFHGAG--CQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEP 1498
Query: 400 ELCGAGSCHNTI---GSFVCQCPDGYSVKPEQGPACTDDDECELGT--------CDCHPA 448
G G CH G C G + P T + +C G CDC
Sbjct: 1499 GSFGEG-CHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGG 1557
Query: 449 ADCINLPGSFQCRCRDGWRGDGATCED 475
ADC P S QC C DG+ G TC +
Sbjct: 1558 ADCD--PVSGQCHCVDGYM--GPTCRE 1580
Score = 37.5 bits (83), Expect = 0.13
Identities = 57/247 (23%), Positives = 76/247 (30%), Gaps = 22/247 (8%)
Query: 129 CGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVN---ECEIVDGVCGDGDCHNTEGSFTC 185
CG G + + G TC C PG C CE G CH + GS +C
Sbjct: 1339 CGQGAACDPVTG-TCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSC 1397
Query: 186 -------HCRPGYKADDFSKICVDIDECADNDALCRG--GRCVNTAGSFRCECGHGMELA 236
HC + C ++ N++ C G C G + C H
Sbjct: 1398 GLGWTGRHCELACPPGRYGAAC-HLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPG 1456
Query: 237 PDRLSCKDIDECSITSGICS--NGACENQMGTYQCVCDEGYAQSTVKS--HXXXXXXXXX 292
C+ + C C +G C G + C+ G + H
Sbjct: 1457 FHGAGCQGLCWCQ-HGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGA 1515
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG--GGQCRNTVGSY 350
C+ PG TC G SC +C GGA C GQC G
Sbjct: 1516 PCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGA-DCDPVSGQCHCVDGYM 1574
Query: 351 TCTCTDG 357
TC +G
Sbjct: 1575 GPTCREG 1581
>Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP1-100N22 on chromosome 22q13.31-13.33. ).
Length = 988
Score = 197 bits (480), Expect = 1e-49
Identities = 142/418 (33%), Positives = 185/418 (44%), Gaps = 57/418 (13%)
Query: 159 VDVNEC-EIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-- 215
VDV+EC E D D C NT S+ C C+PGYK + K C DIDEC +ND G
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGE--GKQCEDIDEC-ENDYYNGGCV 88
Query: 216 GRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+N G++RC C G LA D +C D+DEC +G C C N MG+Y+C C G+
Sbjct: 89 HECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGF 147
Query: 276 A----QSTVKSHXXXXXXXXXXXXRCQHSCVNTP-GSYHCTCREGWHLRADGRSCRDIDE 330
Q T C H C TP G C CR G+ L + + C
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLT-- 205
Query: 331 CAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
C G C C +T TC C + G TC I+ CA + D
Sbjct: 206 CNYGNGGCQHS-CEDTDTGPTCGCHQKYALHSDGR--TC--IETCA-----VNNGGCDR- 254
Query: 391 QKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD 450
+C +T C CP G++++P+ G C D +EC + C
Sbjct: 255 ---------------TCKDTATGVRCSCPVGFTLQPD-GKTCKDINECLVNNGGCDHF-- 296
Query: 451 CINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
C N GSF+C CR G++ D TC+D+DEC H C N+ GSF+CLC GY
Sbjct: 297 CRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDH---ICINSPGSFQCLCHRGYI 353
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
YG C D+DEC+ C+ G C NT G YEC C G +G+ C+
Sbjct: 354 L--YGTT------HCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCV 402
Score = 191 bits (465), Expect = 7e-48
Identities = 130/399 (32%), Positives = 182/399 (45%), Gaps = 48/399 (12%)
Query: 117 MEVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECE--IVDGVCGD 173
++V+EC+ C C+N + C C PGY+ + K C D++ECE +G C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQ--CEDIDECENDYYNGGCVH 89
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
+C N G++ C C G+ C+D+DEC DN+ C+ CVN GS+ C+C G
Sbjct: 90 -ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGF 147
Query: 234 ELAPDRLSC----KDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
L+ ++ +C + C C++ E G C C G+ ++
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGF--DLAQNQKDCTLT 205
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
CQHSC +T C C + + L +DGR+C I+ CA C C++T
Sbjct: 206 CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGCDR-TCKDTATG 262
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
C+C G G TC+DI+EC L++ D C N
Sbjct: 263 VRCSCPVGFTLQPDGK--TCKDINEC--LVNN---GGCDHF----------------CRN 299
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLPGSFQCRCRDGWRG 468
T+GSF C C GY + ++ C D DEC TCD H CIN PGSFQC C G+
Sbjct: 300 TVGSFECGCRKGYKLLTDER-TCQDIDECSFERTCD-HI---CINSPGSFQCLCHRGYIL 354
Query: 469 DGAT-CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
G T C DVDEC +NG C C NT GS+ C+C G
Sbjct: 355 YGTTHCGDVDECSMSNGSCD--QGCVNTKGSYECVCPPG 391
Score = 135 bits (326), Expect = 5e-31
Identities = 77/228 (33%), Positives = 100/228 (43%), Gaps = 10/228 (4%)
Query: 127 GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCH 186
G C H C + G TC C Y S TC++ C + +G C D C +T C
Sbjct: 211 GGCQHS-CEDTDTGPTCGCHQKYALHSDGRTCIET--CAVNNGGC-DRTCKDTATGVRCS 266
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C G+ K C DI+EC N+ C C NT GSF C C G +L D +C+DID
Sbjct: 267 CPVGFTLQPDGKTCKDINECLVNNGGC-DHFCRNTVGSFECGCRKGYKLLTDERTCQDID 325
Query: 247 ECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPG 306
ECS C + C N G++QC+C GY +H C CVNT G
Sbjct: 326 ECSFER-TCDH-ICINSPGSFQCLCHRGYILYGT-THCGDVDECSMSNGSCDQGCVNTKG 382
Query: 307 SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ--CRNTVGSYTC 352
SY C C G L +G+ C + +C A+ Q C G +C
Sbjct: 383 SYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESC 430
Score = 111 bits (267), Expect = 6e-24
Identities = 54/139 (38%), Positives = 76/139 (54%), Gaps = 12/139 (8%)
Query: 430 PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTN--NGGCH 487
P D DEC GT DCH A C N P S++C C+ G++G+G CED+DEC + NGGC
Sbjct: 29 PGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCV 88
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGG 547
C N G++RC C G+ G ++C+D+DEC ++ C+ C N G
Sbjct: 89 HE--CINIPGNYRCTCFDGFMLAHDG-------HNCLDVDECQDNNGGCQQ-ICVNAMGS 138
Query: 548 YECDCDVGFTRAADGRSCL 566
YEC C GF + + +C+
Sbjct: 139 YECQCHSGFFLSDNQHTCI 157
>Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP3-526I14 on chromosome 22. ).
Length = 988
Score = 197 bits (480), Expect = 1e-49
Identities = 142/418 (33%), Positives = 185/418 (44%), Gaps = 57/418 (13%)
Query: 159 VDVNEC-EIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-- 215
VDV+EC E D D C NT S+ C C+PGYK + K C DIDEC +ND G
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGE--GKQCEDIDEC-ENDYYNGGCV 88
Query: 216 GRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+N G++RC C G LA D +C D+DEC +G C C N MG+Y+C C G+
Sbjct: 89 HECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGF 147
Query: 276 A----QSTVKSHXXXXXXXXXXXXRCQHSCVNTP-GSYHCTCREGWHLRADGRSCRDIDE 330
Q T C H C TP G C CR G+ L + + C
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLT-- 205
Query: 331 CAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
C G C C +T TC C + G TC I+ CA + D
Sbjct: 206 CNYGNGGCQHS-CEDTDTGPTCGCHQKYALHSDGR--TC--IETCA-----VNNGGCDR- 254
Query: 391 QKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD 450
+C +T C CP G++++P+ G C D +EC + C
Sbjct: 255 ---------------TCKDTATGVRCSCPVGFTLQPD-GKTCKDINECLVNNGGCDHF-- 296
Query: 451 CINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
C N GSF+C CR G++ D TC+D+DEC H C N+ GSF+CLC GY
Sbjct: 297 CRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDH---ICINSPGSFQCLCHRGYI 353
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
YG C D+DEC+ C+ G C NT G YEC C G +G+ C+
Sbjct: 354 L--YGTT------HCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCV 402
Score = 191 bits (465), Expect = 7e-48
Identities = 130/399 (32%), Positives = 182/399 (45%), Gaps = 48/399 (12%)
Query: 117 MEVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECE--IVDGVCGD 173
++V+EC+ C C+N + C C PGY+ + K C D++ECE +G C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQ--CEDIDECENDYYNGGCVH 89
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
+C N G++ C C G+ C+D+DEC DN+ C+ CVN GS+ C+C G
Sbjct: 90 -ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGF 147
Query: 234 ELAPDRLSC----KDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
L+ ++ +C + C C++ E G C C G+ ++
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGF--DLAQNQKDCTLT 205
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
CQHSC +T C C + + L +DGR+C I+ CA C C++T
Sbjct: 206 CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGCDR-TCKDTATG 262
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
C+C G G TC+DI+EC L++ D C N
Sbjct: 263 VRCSCPVGFTLQPDGK--TCKDINEC--LVNN---GGCDHF----------------CRN 299
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLPGSFQCRCRDGWRG 468
T+GSF C C GY + ++ C D DEC TCD H CIN PGSFQC C G+
Sbjct: 300 TVGSFECGCRKGYKLLTDER-TCQDIDECSFERTCD-HI---CINSPGSFQCLCHRGYIL 354
Query: 469 DGAT-CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
G T C DVDEC +NG C C NT GS+ C+C G
Sbjct: 355 YGTTHCGDVDECSMSNGSCD--QGCVNTKGSYECVCPPG 391
Score = 135 bits (326), Expect = 5e-31
Identities = 77/228 (33%), Positives = 100/228 (43%), Gaps = 10/228 (4%)
Query: 127 GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCH 186
G C H C + G TC C Y S TC++ C + +G C D C +T C
Sbjct: 211 GGCQHS-CEDTDTGPTCGCHQKYALHSDGRTCIET--CAVNNGGC-DRTCKDTATGVRCS 266
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C G+ K C DI+EC N+ C C NT GSF C C G +L D +C+DID
Sbjct: 267 CPVGFTLQPDGKTCKDINECLVNNGGC-DHFCRNTVGSFECGCRKGYKLLTDERTCQDID 325
Query: 247 ECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPG 306
ECS C + C N G++QC+C GY +H C CVNT G
Sbjct: 326 ECSFER-TCDH-ICINSPGSFQCLCHRGYILYGT-THCGDVDECSMSNGSCDQGCVNTKG 382
Query: 307 SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ--CRNTVGSYTC 352
SY C C G L +G+ C + +C A+ Q C G +C
Sbjct: 383 SYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESC 430
Score = 111 bits (267), Expect = 6e-24
Identities = 54/139 (38%), Positives = 76/139 (54%), Gaps = 12/139 (8%)
Query: 430 PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTN--NGGCH 487
P D DEC GT DCH A C N P S++C C+ G++G+G CED+DEC + NGGC
Sbjct: 29 PGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCV 88
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGG 547
C N G++RC C G+ G ++C+D+DEC ++ C+ C N G
Sbjct: 89 HE--CINIPGNYRCTCFDGFMLAHDG-------HNCLDVDECQDNNGGCQQ-ICVNAMGS 138
Query: 548 YECDCDVGFTRAADGRSCL 566
YEC C GF + + +C+
Sbjct: 139 YECQCHSGFFLSDNQHTCI 157
>AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein.
Length = 915
Score = 197 bits (480), Expect = 1e-49
Identities = 126/392 (32%), Positives = 172/392 (43%), Gaps = 41/392 (10%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C+ GY + C D CA D C CVN GSF C+C G L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
A D C +D C+ + C + C N G+Y C C EG+A + +
Sbjct: 312 AEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTRINYCALNKP 370
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
C+H CVN SY+C C G+ L +G++C +D CA C C NT S+ C C+
Sbjct: 371 GCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCS 429
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
+G + + TC +D C ++S + S C N SF
Sbjct: 430 EGFLINED--LKTCSRVDYC--------LLSDHGCEYS-------------CVNMDRSFA 466
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATC 473
CQCP+G+ ++ + G C D C LG C + C++ SF C+C +G+ R DG TC
Sbjct: 467 CQCPEGHVLRSD-GKTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTC 523
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDP 533
D C + GC C N+D S+ C C G++ G R C D C +
Sbjct: 524 RRKDVCQAIDHGCEH--ICVNSDDSYTCECLEGFRLAEDGKR-------CRRKDVCKSTH 574
Query: 534 TLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
CE+ C N Y C C GF A DGR C
Sbjct: 575 HGCEH-ICVNNGNSYICKCSEGFVLAEDGRRC 605
Score = 188 bits (458), Expect = 5e-47
Identities = 121/407 (29%), Positives = 169/407 (41%), Gaps = 35/407 (8%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C+ C H C N+ G + C C GY +S TC + C + D C + C N G
Sbjct: 242 CSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC-EQLCVNVPG 299
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
SF C C GY + K CV +D CA + C CVN GS+ C+C G L PD +
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCE-HECVNADGSYLCQCHEGFALNPDEKT 358
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C I+ C++ C + C N +Y C C GY C+ C
Sbjct: 359 CTRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLC 417
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS 361
+NT S+ C C EG+ + D ++C +D C C C N S+ C C +G V
Sbjct: 418 LNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGC-EYSCVNMDRSFACQCPEGHVLR 476
Query: 362 AAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDG 421
+ G TC +D CA + + SC ++ SFVCQC +G
Sbjct: 477 SDG--KTCAKLDSCA---------------------LGDHGCEHSCVSSEDSFVCQCFEG 513
Query: 422 YSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDEC 479
Y ++ E G C D C+ C C+N S+ C C +G+R DG C D C
Sbjct: 514 YILR-EDGKTCRRKDVCQAIDHGCEHI--CVNSDDSYTCECLEGFRLAEDGKRCRRKDVC 570
Query: 480 LTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI 526
+ + GC C N S+ C C G+ G R C +D+
Sbjct: 571 KSTHHGC--EHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDL 615
Score = 166 bits (404), Expect = 2e-40
Identities = 113/355 (31%), Positives = 152/355 (42%), Gaps = 44/355 (12%)
Query: 218 CVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ 277
C+N GS+ C C G L D+ +C+ D C++ C C N G++ C C GYA
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 278 STVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARP 337
+ C+H CVN GSY C C EG+ L D ++C I+ CA
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTRINYCALNKPG 371
Query: 338 CGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
C +C N SY C C G G TC +D CA D
Sbjct: 372 CEH-ECVNMEESYYCRCHRGYTLDPNGK--TCSRVDHCAQQ----------------DHG 412
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
+LC NT SFVCQC +G+ + E C+ D C L C + C+N+ S
Sbjct: 413 CEQLC-----LNTEDSFVCQCSEGFLIN-EDLKTCSRVDYCLLSDHGCEYS--CVNMDRS 464
Query: 458 FQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY--KGDGYG 513
F C+C +G R DG TC +D C + GC +C +++ SF C C GY + DG
Sbjct: 465 FACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH--SCVSSEDSFVCQCFEGYILREDGK- 521
Query: 514 LRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
+C D C CE+ C N+ Y C+C GF A DG+ C K
Sbjct: 522 --------TCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRK 567
Score = 151 bits (365), Expect = 9e-36
Identities = 82/257 (31%), Positives = 117/257 (45%), Gaps = 7/257 (2%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
V+ CA+ C H C N G + C C G+ + TC +N C + C + +C N
Sbjct: 321 VDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDEKTCTRINYCALNKPGC-EHECVN 378
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
E S+ C C GY D K C +D CA D C C+NT SF C+C G + D
Sbjct: 379 MEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINED 437
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
+C +D C ++ C +C N ++ C C EG+ + C+
Sbjct: 438 LKTCSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE 496
Query: 299 HSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL 358
HSCV++ S+ C C EG+ LR DG++CR D C C C N+ SYTC C +G
Sbjct: 497 HSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGF 555
Query: 359 VPSAAGAKPTCQDIDEC 375
+ G + C+ D C
Sbjct: 556 RLAEDGKR--CRRKDVC 570
Score = 145 bits (351), Expect = 4e-34
Identities = 81/248 (32%), Positives = 109/248 (43%), Gaps = 5/248 (2%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
+N CA C H C N+ + C C GY D TC V+ C D C + C N
Sbjct: 362 INYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGC-EQLCLN 419
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
TE SF C C G+ ++ K C +D C +D C CVN SF C+C G L D
Sbjct: 420 TEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYS-CVNMDRSFACQCPEGHVLRSD 478
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
+C +D C++ C + +C + ++ C C EGY C+
Sbjct: 479 GKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCE 537
Query: 299 HSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL 358
H CVN+ SY C C EG+ L DG+ CR D C C C N SY C C++G
Sbjct: 538 HICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGC-EHICVNNGNSYICKCSEGF 596
Query: 359 VPSAAGAK 366
V + G +
Sbjct: 597 VLAEDGRR 604
Score = 116 bits (278), Expect = 3e-25
Identities = 67/212 (31%), Positives = 88/212 (41%), Gaps = 4/212 (1%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
V+ CA C C N F C C G+ + TC V+ C + D C + C N
Sbjct: 403 VDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGC-EYSCVN 460
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
+ SF C C G+ K C +D CA D C CV++ SF C+C G L D
Sbjct: 461 MDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS-CVSSEDSFVCQCFEGYILRED 519
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
+C+ D C C + C N +Y C C EG+ + C+
Sbjct: 520 GKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCE 578
Query: 299 HSCVNTPGSYHCTCREGWHLRADGRSCRDIDE 330
H CVN SY C C EG+ L DGR C+ E
Sbjct: 579 HICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 610
>AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ16792 fis, clone TBAES2007379, moderately
similar to Homo sapiens signal peptide, CUB domain,
EGF-like 2 (SCUBE2). ).
Length = 682
Score = 196 bits (477), Expect = 2e-49
Identities = 137/427 (32%), Positives = 195/427 (45%), Gaps = 48/427 (11%)
Query: 160 DVNEC-EIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-- 216
DV+EC + +D D C NT S+ C C+PGY+ + + C DIDEC + GG
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGE--GRQCEDIDECGNE---LNGGCV 99
Query: 217 -RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+N G++RC C G LA D +C D+DEC +G C + C N MG+Y+C C EG+
Sbjct: 100 HDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGF 158
Query: 276 ----AQSTVKSHXXXXXXXXXXXXRCQHSCVNTP-GSYHCTCREGWHLRADGRSCRDIDE 330
Q T C H C P GS C CR G+ L + R C I
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILT 216
Query: 331 CAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
C G C C +T C+C G +C + ++ ++ SV +
Sbjct: 217 CNHGNGGC-QHSCDDTADGPECSCHPQYKMHTDGR--SCLEREDTVLEVTESNTTSVVDG 273
Query: 391 QKSVDPQ-IPELCGAG------SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECEL--G 441
K V Q + E C +C +T C CP G++++ + G C D DEC+ G
Sbjct: 274 DKRVKRQLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLD-GKTCKDIDECQTRNG 332
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSF 499
CD H C N+ GSF C C+ G++ D +C+DVDEC + H +C N G+F
Sbjct: 333 GCD-H---FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH---SCINHPGTF 385
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRA 559
C C+ GY G+ C D +EC+ + C+ C NT G YEC C G+
Sbjct: 386 ACACNRGYTLYGF--------THCGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKLH 436
Query: 560 ADGRSCL 566
+ + C+
Sbjct: 437 WNKKDCV 443
Score = 186 bits (454), Expect = 1e-46
Identities = 127/412 (30%), Positives = 184/412 (44%), Gaps = 39/412 (9%)
Query: 116 QMEVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC-EIVDGVCGD 173
Q +V+ECA C C+N + C C PGY+ + + C D++EC ++G C
Sbjct: 43 QEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNELNGGCVH 100
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
DC N G++ C C G+ C+D+DEC +N+ C+ CVN GS+ C C G
Sbjct: 101 -DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQ-HTCVNVMGSYECCCKEGF 158
Query: 234 ELAPDRLSCKDIDE----CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
L+ ++ +C E C CS+ E G+ C C G+ K+
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGF--ELAKNQRDCILT 216
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-------RDIDECAGGARPCGGGQ 342
CQHSC +T C+C + + DGRSC ++ E + G +
Sbjct: 217 CNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKR 276
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDID---ECADLISTIIMMSVDELQKSVDPQIP 399
+ + TC +G G TC+D C+ + + + + K +D
Sbjct: 277 VKRQLLMETCAVNNG------GCDRTCKDTSTGVHCSCPVGFTLQLD-GKTCKDIDECQT 329
Query: 400 ELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLPGS 457
G C N +GSF C C G+ + ++ +C D DEC L TCD H CIN PG+
Sbjct: 330 RNGGCDHFCKNIVGSFDCGCKKGFKLLTDE-KSCQDVDECSLDRTCD-H---SCINHPGT 384
Query: 458 FQCRCRDGWRGDGAT-CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
F C C G+ G T C D +EC NNGGC + C NT GS+ C C GYK
Sbjct: 385 FACACNRGYTLYGFTHCGDTNECSINNGGC--QQVCVNTVGSYECQCHPGYK 434
Score = 106 bits (255), Expect = 2e-22
Identities = 56/148 (37%), Positives = 79/148 (53%), Gaps = 14/148 (9%)
Query: 423 SVKPEQGPAC---TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDEC 479
+V P +G A D DEC G DCH A C N P S++C C+ G++G+G CED+DEC
Sbjct: 31 AVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDEC 90
Query: 480 LTN-NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN 538
NGGC C N G++RC C G+ G ++C+D+DEC + C++
Sbjct: 91 GNELNGGC--VHDCLNIPGNYRCTCFDGFMLAHDG-------HNCLDVDECLENNGGCQH 141
Query: 539 GHCSNTPGGYECDCDVGFTRAADGRSCL 566
C N G YEC C GF + + +C+
Sbjct: 142 -TCVNVMGSYECCCKEGFFLSDNQHTCI 168
Score = 93.1 bits (221), Expect = 2e-18
Identities = 46/125 (36%), Positives = 69/125 (55%), Gaps = 5/125 (4%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC G C H C+N++G F C C G++ + +C DV+EC + D C D C
Sbjct: 323 DIDECQTRNGGCDHF-CKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSL-DRTC-DHSCI 379
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G+F C C GY F+ C D +EC+ N+ C+ CVNT GS+ C+C G +L
Sbjct: 380 NHPGTFACACNRGYTLYGFTH-CGDTNECSINNGGCQ-QVCVNTVGSYECQCHPGYKLHW 437
Query: 238 DRLSC 242
++ C
Sbjct: 438 NKKDC 442
Score = 34.3 bits (75), Expect = 1.2
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV 159
+ NEC+ G C C N +G + C C PGY+ CV
Sbjct: 403 DTNECSINNGGCQQV-CVNTVGSYECQCHPGYKLHWNKKDCV 443
>AF525689-1|AAN77133.1| 988|Homo sapiens signal
peptide-CUB-EGF-like domain containing protein 1
protein.
Length = 988
Score = 195 bits (476), Expect = 3e-49
Identities = 140/407 (34%), Positives = 180/407 (44%), Gaps = 57/407 (14%)
Query: 159 VDVNEC-EIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-- 215
VDV+EC E D D C N S+ C C+PGYK + K C DIDEC +ND G
Sbjct: 32 VDVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGE--GKQCGDIDEC-ENDYYNGGCV 88
Query: 216 GRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+N G++RC C G LA D +C D+DEC +G C C N MG+Y+C C G+
Sbjct: 89 HECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGF 147
Query: 276 A----QSTVKSHXXXXXXXXXXXXRCQHSCVNTP-GSYHCTCREGWHLRADGRSCRDIDE 330
Q T C H C TP G C CR G+ L + + C
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLT-- 205
Query: 331 CAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
C G C C +T TC C P + G TC I+ CA + D
Sbjct: 206 CNYGNGGCQHS-CEDTDTGPTCGCHQKYAPHSDGR--TC--IETCA-----VNNGGCDR- 254
Query: 391 QKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD 450
+C +T C CP G++++P+ G C D +EC + C
Sbjct: 255 ---------------TCKDTATGVRCSCPVGFTLQPD-GKTCKDINECLVNNGGCDHF-- 296
Query: 451 CINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
C N GSF+C CR G++ D TC+D+DEC H C N+ GSF+CLC GY
Sbjct: 297 CRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDH---ICINSPGSFQCLCHRGYI 353
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
YG C D+DEC+ C+ G C NT G YEC C G
Sbjct: 354 L--YGTT------HCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPG 391
Score = 188 bits (457), Expect = 6e-47
Identities = 129/399 (32%), Positives = 181/399 (45%), Gaps = 48/399 (12%)
Query: 117 MEVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECE--IVDGVCGD 173
++V+EC+ C C+N + C C PGY+ + K C D++ECE +G C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGEGKQ--CGDIDECENDYYNGGCVH 89
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
+C N G++ C C G+ C+D+DEC DN+ C+ CVN GS+ C+C G
Sbjct: 90 -ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQ-QICVNAMGSYECQCHSGF 147
Query: 234 ELAPDRLSC----KDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
L+ ++ +C + C C++ E G C C G+ ++
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGF--DLAQNQKDCTLT 205
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
CQHSC +T C C + + +DGR+C I+ CA C C++T
Sbjct: 206 CNYGNGGCQHSCEDTDTGPTCGCHQKYAPHSDGRTC--IETCAVNNGGC-DRTCKDTATG 262
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
C+C G G TC+DI+EC L++ D C N
Sbjct: 263 VRCSCPVGFTLQPDG--KTCKDINEC--LVNN---GGCDHF----------------CRN 299
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECEL-GTCDCHPAADCINLPGSFQCRCRDGWRG 468
T+GSF C C GY + ++ C D DEC TCD H CIN PGSFQC C G+
Sbjct: 300 TVGSFECGCRKGYKLLTDE-RTCQDIDECSFERTCD-H---ICINSPGSFQCLCHRGYIL 354
Query: 469 DGAT-CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
G T C DVDEC +NG C C NT GS+ C+C G
Sbjct: 355 YGTTHCGDVDECSMSNGSCD--QGCVNTKGSYECVCPPG 391
Score = 157 bits (382), Expect = 7e-38
Identities = 114/394 (28%), Positives = 167/394 (42%), Gaps = 47/394 (11%)
Query: 118 EVNECAA--FPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
+++EC + G C H C N+ G + C CF G+ H C+DV+EC+ +G C
Sbjct: 74 DIDECENDYYNGGCVH-ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGC-QQI 131
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDID----ECADNDALCRGGRCVNTAGSFRCECGH 231
C N GS+ C C G+ D C+ C + D C G C+C
Sbjct: 132 CVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRP 191
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
G +LA ++ C C+ +G C + +CE+ C C + YA +
Sbjct: 192 GFDLAQNQKDC--TLTCNYGNGGCQH-SCEDTDTGPTCGCHQKYAPHS--DGRTCIETCA 246
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
C +C +T C+C G+ L+ DG++C+DI+EC C CRNTVGS+
Sbjct: 247 VNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGC-DHFCRNTVGSFE 305
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
C C G + TCQDIDEC+ +++ D C N+
Sbjct: 306 CGCRKGY--KLLTDERTCQDIDECS-------------FERTCD---------HICINSP 341
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GD 469
GSF C C GY + C D DEC + C C+N GS++C C G R +
Sbjct: 342 GSFQCLCHRGYILYGT--THCGDVDECSMSNGSCDQG--CVNTKGSYECVCPPGRRLHWN 397
Query: 470 GATCEDVDECLTNNGGCHPRA--TCANTDGSFRC 501
C + +CL + PRA +C+ G C
Sbjct: 398 RKDCVETGKCL-SRAKTSPRAQLSCSKAGGVESC 430
Score = 152 bits (368), Expect = 4e-36
Identities = 106/337 (31%), Positives = 147/337 (43%), Gaps = 41/337 (12%)
Query: 244 DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
D+DECS + C A C+N +Y+C+C GY + C H C+
Sbjct: 33 DVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGEGKQCGDIDECENDYYNGGCVHECI 92
Query: 303 NTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS- 361
N PG+Y CTC +G+ L DG +C D+DEC C C N +GSY C C G S
Sbjct: 93 NIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGFFLSD 151
Query: 362 -------AAGAKPTCQDIDE-CADL--------ISTIIMMSVDELQKSVDPQIPELCGAG 405
+ C + D CA + ++ D Q D + G G
Sbjct: 152 NQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNG 211
Query: 406 ----SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR 461
SC +T C C Y+ + G C + G CD C + +C
Sbjct: 212 GCQHSCEDTDTGPTCGCHQKYAPHSD-GRTCIETCAVNNGGCD----RTCKDTATGVRCS 266
Query: 462 CRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C G+ + DG TC+D++ECL NNGGC C NT GSF C C GYK +
Sbjct: 267 CPVGFTLQPDGKTCKDINECLVNNGGCD--HFCRNTVGSFECGCRKGYK-------LLTD 317
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
+C DIDEC+ + T C++ C N+PG ++C C G+
Sbjct: 318 ERTCQDIDECSFERT-CDH-ICINSPGSFQCLCHRGY 352
Score = 108 bits (260), Expect = 4e-23
Identities = 53/139 (38%), Positives = 75/139 (53%), Gaps = 12/139 (8%)
Query: 430 PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTN--NGGCH 487
P D DEC GT DCH A C N P S++C C+ G++G+G C D+DEC + NGGC
Sbjct: 29 PGSVDVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGEGKQCGDIDECENDYYNGGCV 88
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGG 547
C N G++RC C G+ G ++C+D+DEC ++ C+ C N G
Sbjct: 89 HE--CINIPGNYRCTCFDGFMLAHDG-------HNCLDVDECQDNNGGCQQ-ICVNAMGS 138
Query: 548 YECDCDVGFTRAADGRSCL 566
YEC C GF + + +C+
Sbjct: 139 YECQCHSGFFLSDNQHTCI 157
Score = 105 bits (251), Expect = 6e-22
Identities = 59/162 (36%), Positives = 78/162 (48%), Gaps = 12/162 (7%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N S+ C C GY +G C D DECE + +CIN+PG+++C C DG+
Sbjct: 50 CQNAPKSYKCLCKPGYK---GEGKQCGDIDECENDYYNGGCVHECINIPGNYRCTCFDGF 106
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
DG C DVDEC NNGGC + C N GS+ C C +G+ C++
Sbjct: 107 MLAHDGHNCLDVDECQDNNGGC--QQICVNAMGSYECQCHSGF---FLSDNQHTCIHRSN 161
Query: 525 DIDECANDPTLCENGHCSNTP-GGYECDCDVGFTRAADGRSC 565
+ C N C + C TP GG CDC GF A + + C
Sbjct: 162 EGMNCMNKDHGCAH-ICRETPKGGVACDCRPGFDLAQNQKDC 202
Score = 101 bits (242), Expect = 7e-21
Identities = 83/268 (30%), Positives = 110/268 (41%), Gaps = 40/268 (14%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTCTDGLV 359
C N P SY C C+ G+ + +G+ C DIDEC G +C N G+Y CTC DG +
Sbjct: 50 CQNAPKSYKCLCKPGY--KGEGKQCGDIDECENDYYNGGCVHECINIPGNYRCTCFDGFM 107
Query: 360 PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCP 419
+ G C D+DEC D QI C N +GS+ CQC
Sbjct: 108 LAHDGHN--CLDVDECQD-------------NNGGCQQI--------CVNAMGSYECQCH 144
Query: 420 DGYSVKPEQGPACTDDDECELGTCDCHPAAD-CINLP-GSFQCRCRDGWRGDGATCEDVD 477
G+ + Q +E H A C P G C CR G+ +
Sbjct: 145 SGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTL 204
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
C NGGC + +C +TD C C Y G RT C+ +C ++ D T
Sbjct: 205 TCNYGNGGC--QHSCEDTDTGPTCGCHQKYAPHSDG-RT--CIETCA-VNNGGCDRT--- 255
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
C +T G C C VGFT DG++C
Sbjct: 256 ---CKDTATGVRCSCPVGFTLQPDGKTC 280
Score = 70.5 bits (165), Expect = 1e-11
Identities = 67/248 (27%), Positives = 95/248 (38%), Gaps = 46/248 (18%)
Query: 327 DIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
D+DEC+ G C C+N SY C C P G C DIDEC +
Sbjct: 33 DVDECSEGTDDCHIDAICQNAPKSYKCLCK----PGYKGEGKQCGDIDECEN-------- 80
Query: 386 SVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
D C C N G++ C C DG+ + + G C D DEC+ C
Sbjct: 81 --DYYNGG--------C-VHECINIPGNYRCTCFDGFMLAHD-GHNCLDVDECQDNNGGC 128
Query: 446 HPAADCINLPGSFQCRCRDGW--RGDGATC----EDVDECLTNNGGCHPRATCANTD-GS 498
C+N GS++C+C G+ + TC + C+ + GC C T G
Sbjct: 129 QQI--CVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGC--AHICRETPKGG 184
Query: 499 FRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTR 558
C C G+ C +C N C++ C +T G C C +
Sbjct: 185 VACDCRPGFD---LAQNQKDCTLTC----NYGNGG--CQHS-CEDTDTGPTCGCHQKYAP 234
Query: 559 AADGRSCL 566
+DGR+C+
Sbjct: 235 HSDGRTCI 242
>Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA sequence
from clone RP3-329A5 on chromosome 6p21.1-21.33. ).
Length = 993
Score = 194 bits (473), Expect = 7e-49
Identities = 131/396 (33%), Positives = 173/396 (43%), Gaps = 45/396 (11%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC C C+N + C C GY D K+ C DV+ECE D DC
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKH--CKDVDECEREDNAGCVHDC 86
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G++ C C G+ C+D+DECA+ + C+ CVN GS+ C C G L+
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLS 145
Query: 237 PDRLSCKDIDE----CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
++ +C E C + C++ E G C C G+ K+
Sbjct: 146 DNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGF--ELTKNQRDCKLTCNY 203
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
CQH+C +T C C + L DG++C I+ CA C +C + C
Sbjct: 204 GNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGC-DSKCHDAATGVHC 260
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
TC G + + TC+DIDEC L I C NT+G
Sbjct: 261 TCPVGFM--LQPDRKTCKDIDEC-------------RLNNGGCDHI--------CRNTVG 297
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
SF C C GY + + C D DEC TCD H C+N PGSFQC C G+ G
Sbjct: 298 SFECSCKKGYKLLINE-RNCQDIDECSFDRTCD-H---ICVNTPGSFQCLCHRGYLLYGI 352
Query: 472 T-CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
T C DVDEC N GGC R C NT GS++C C G
Sbjct: 353 THCGDVDECSINRGGC--RFGCINTPGSYQCTCPAG 386
Score = 173 bits (422), Expect = 1e-42
Identities = 122/397 (30%), Positives = 168/397 (42%), Gaps = 41/397 (10%)
Query: 192 KADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSI 250
+A +SK D+DEC + C C NT S++C C G D CKD+DEC
Sbjct: 19 RAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECER 76
Query: 251 TSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHC 310
C N G Y+C C +G+ + + CQ SCVN GSY C
Sbjct: 77 EDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYEC 136
Query: 311 TCREGWHLRADGRSCRDIDE----CAGGARPCGGGQCRNTV-GSYTCTCTDGLVPSA--- 362
CREG+ L + +C E C C CR T G C C G +
Sbjct: 137 HCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH-ICRETPKGGIACECRPGFELTKNQR 195
Query: 363 ----------AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTI 411
G + TC D ++ I + + + ++ G S CH+
Sbjct: 196 DCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAA 255
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--D 469
C CP G+ ++P++ C D DEC L C C N GSF+C C+ G++ +
Sbjct: 256 TGVHCTCPVGFMLQPDR-KTCKDIDECRLNNGGCDHI--CRNTVGSFECSCKKGYKLLIN 312
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
C+D+DEC + H C NT GSF+CLC GY YG+ C D+DEC
Sbjct: 313 ERNCQDIDECSFDRTCDH---ICVNTPGSFQCLCHRGYLL--YGIT------HCGDVDEC 361
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAA-DGRSC 565
+ + C G C NTPG Y+C C G R +G+ C
Sbjct: 362 SINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDC 397
Score = 128 bits (308), Expect = 7e-29
Identities = 71/208 (34%), Positives = 97/208 (46%), Gaps = 9/208 (4%)
Query: 127 GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCH 186
G C H C + G C C + + TC++ C + +G C D CH+ C
Sbjct: 206 GGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTCIET--CAVNNGGC-DSKCHDAATGVHCT 261
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C G+ K C DIDEC N+ C C NT GSF C C G +L + +C+DID
Sbjct: 262 CPVGFMLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDID 320
Query: 247 ECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPG 306
ECS C + C N G++QC+C GY + +H C+ C+NTPG
Sbjct: 321 ECSFDR-TCDH-ICVNTPGSFQCLCHRGYLLYGI-THCGDVDECSINRGGCRFGCINTPG 377
Query: 307 SYHCTCREG-WHLRADGRSCRDIDECAG 333
SY CTC G L +G+ C + +C G
Sbjct: 378 SYQCTCPAGQGRLHWNGKDCTEPLKCQG 405
Score = 124 bits (299), Expect = 8e-28
Identities = 92/327 (28%), Positives = 135/327 (41%), Gaps = 37/327 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE----CEIVDGVCG 172
++V+ECA G C C N++G + C C G+ HTC+ E C + C
Sbjct: 111 LDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCA 169
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
+G C CRPG++ + C C + C+ C +T RC C
Sbjct: 170 HICRETPKGGIACECRPGFELTKNQRDCKLT--CNYGNGGCQH-TCDDTEQGPRCGCHIK 226
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
L D +C I+ C++ +G C + C + C C G+ +
Sbjct: 227 FVLHTDGKTC--IETCAVNNGGCDS-KCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRL 283
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C H C NT GS+ C+C++G+ L + R+C+DIDEC+ R C C NT GS+ C
Sbjct: 284 NNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFD-RTC-DHICVNTPGSFQC 341
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C G + C D+DEC S++ C G C NT G
Sbjct: 342 LCHRGYLLYGI---THCGDVDEC----------SINR----------GGCRFG-CINTPG 377
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECE 439
S+ C CP G G CT+ +C+
Sbjct: 378 SYQCTCPAGQGRLHWNGKDCTEPLKCQ 404
Score = 105 bits (252), Expect = 4e-22
Identities = 54/137 (39%), Positives = 73/137 (53%), Gaps = 11/137 (8%)
Query: 431 ACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDEC-LTNNGGCHPR 489
A D DEC GT +CH A C N P S++C C+ G+ GDG C+DVDEC +N GC
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGC--V 83
Query: 490 ATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYE 549
C N G++RC C G+ G ++C+D+DECA C+ C N G YE
Sbjct: 84 HDCVNIPGNYRCTCYDGFHLAHDG-------HNCLDVDECAEGNGGCQQS-CVNMMGSYE 135
Query: 550 CDCDVGFTRAADGRSCL 566
C C GF + + +C+
Sbjct: 136 CHCREGFFLSDNQHTCI 152
>BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein.
Length = 807
Score = 194 bits (473), Expect = 7e-49
Identities = 136/427 (31%), Positives = 195/427 (45%), Gaps = 48/427 (11%)
Query: 160 DVNEC-EIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-- 216
DV+EC + +D D C NT S+ C C+PGY+ + + C DIDEC + GG
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGE--GRQCEDIDECGNE---LNGGCV 99
Query: 217 -RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+N G++RC C G LA D +C D+DEC +G C + C N MG+Y+C C EG+
Sbjct: 100 HDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGF 158
Query: 276 ----AQSTVKSHXXXXXXXXXXXXRCQHSCVNTP-GSYHCTCREGWHLRADGRSCRDIDE 330
Q T C H C P GS C CR G+ L + R C I
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILT 216
Query: 331 CAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
C G C C +T C+C G +C + ++ ++ SV +
Sbjct: 217 CNHGNGGC-QHSCDDTADGPECSCHPQYKMHTDGR--SCLEREDTVLEVTESNTTSVVDG 273
Query: 391 QKSVDPQ-IPELCGAG------SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECEL--G 441
K V + + E C +C +T C CP G++++ + G C D DEC+ G
Sbjct: 274 DKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLD-GKTCKDIDECQTRNG 332
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSF 499
CD H C N+ GSF C C+ G++ D +C+DVDEC + H +C N G+F
Sbjct: 333 GCD-H---FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH---SCINHPGTF 385
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRA 559
C C+ GY G+ C D +EC+ + C+ C NT G YEC C G+
Sbjct: 386 ACACNRGYTLYGF--------THCGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKLH 436
Query: 560 ADGRSCL 566
+ + C+
Sbjct: 437 WNKKDCV 443
Score = 186 bits (454), Expect = 1e-46
Identities = 127/412 (30%), Positives = 184/412 (44%), Gaps = 39/412 (9%)
Query: 116 QMEVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC-EIVDGVCGD 173
Q +V+ECA C C+N + C C PGY+ + + C D++EC ++G C
Sbjct: 43 QEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNELNGGCVH 100
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
DC N G++ C C G+ C+D+DEC +N+ C+ CVN GS+ C C G
Sbjct: 101 -DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQ-HTCVNVMGSYECCCKEGF 158
Query: 234 ELAPDRLSCKDIDE----CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
L+ ++ +C E C CS+ E G+ C C G+ K+
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGF--ELAKNQRDCILT 216
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-------RDIDECAGGARPCGGGQ 342
CQHSC +T C+C + + DGRSC ++ E + G +
Sbjct: 217 CNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKR 276
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDID---ECADLISTIIMMSVDELQKSVDPQIP 399
+ + TC +G G TC+D C+ + + + + K +D
Sbjct: 277 VKRRLLMETCAVNNG------GCDRTCKDTSTGVHCSCPVGFTLQLD-GKTCKDIDECQT 329
Query: 400 ELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLPGS 457
G C N +GSF C C G+ + ++ +C D DEC L TCD H CIN PG+
Sbjct: 330 RNGGCDHFCKNIVGSFDCGCKKGFKLLTDE-KSCQDVDECSLDRTCD-H---SCINHPGT 384
Query: 458 FQCRCRDGWRGDGAT-CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
F C C G+ G T C D +EC NNGGC + C NT GS+ C C GYK
Sbjct: 385 FACACNRGYTLYGFTHCGDTNECSINNGGC--QQVCVNTVGSYECQCHPGYK 434
Score = 106 bits (255), Expect = 2e-22
Identities = 56/148 (37%), Positives = 79/148 (53%), Gaps = 14/148 (9%)
Query: 423 SVKPEQGPAC---TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDEC 479
+V P +G A D DEC G DCH A C N P S++C C+ G++G+G CED+DEC
Sbjct: 31 AVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDEC 90
Query: 480 LTN-NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN 538
NGGC C N G++RC C G+ G ++C+D+DEC + C++
Sbjct: 91 GNELNGGC--VHDCLNIPGNYRCTCFDGFMLAHDG-------HNCLDVDECLENNGGCQH 141
Query: 539 GHCSNTPGGYECDCDVGFTRAADGRSCL 566
C N G YEC C GF + + +C+
Sbjct: 142 -TCVNVMGSYECCCKEGFFLSDNQHTCI 168
Score = 93.1 bits (221), Expect = 2e-18
Identities = 46/125 (36%), Positives = 69/125 (55%), Gaps = 5/125 (4%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC G C H C+N++G F C C G++ + +C DV+EC + D C D C
Sbjct: 323 DIDECQTRNGGCDHF-CKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSL-DRTC-DHSCI 379
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G+F C C GY F+ C D +EC+ N+ C+ CVNT GS+ C+C G +L
Sbjct: 380 NHPGTFACACNRGYTLYGFTH-CGDTNECSINNGGCQ-QVCVNTVGSYECQCHPGYKLHW 437
Query: 238 DRLSC 242
++ C
Sbjct: 438 NKKDC 442
Score = 34.3 bits (75), Expect = 1.2
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV 159
+ NEC+ G C C N +G + C C PGY+ CV
Sbjct: 403 DTNECSINNGGCQQV-CVNTVGSYECQCHPGYKLHWNKKDCV 443
>BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB
domain, EGF-like 3 protein.
Length = 992
Score = 194 bits (473), Expect = 7e-49
Identities = 131/395 (33%), Positives = 173/395 (43%), Gaps = 44/395 (11%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC C C+N + C C GY D K+ C DV+ECE D DC
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKH--CKDVDECEREDNAGCVHDC 86
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G++ C C G+ C+D+DECA+ + C+ CVN GS+ C C G L+
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLS 145
Query: 237 PDRLSCKDIDE---CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
++ +C E C + C++ E G C C G+ K+
Sbjct: 146 DNQHTCIQRPEGMNCMNKNHGCAHICRETPKGGIACECRPGF--ELTKNQRDCKLTCNYG 203
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
CQH+C +T C C + L DG++C I+ CA C +C + CT
Sbjct: 204 NGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGC-DSKCHDAAIGVHCT 260
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G + + TC+DIDEC L I C NT+GS
Sbjct: 261 CPVGFM--LQPDRKTCKDIDEC-------------RLNNGGCDHI--------CRNTVGS 297
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLPGSFQCRCRDGWRGDGAT 472
F C C GY + + C D DEC TCD H C+N PGSFQC C G+ G T
Sbjct: 298 FECSCKKGYKLLINE-RNCQDIDECSFDRTCD-H---ICVNTPGSFQCLCHRGYLLYGIT 352
Query: 473 -CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
C DVDEC N GGC R C NT GS++C C G
Sbjct: 353 HCGDVDECSINRGGC--RFGCINTPGSYQCTCPAG 385
Score = 173 bits (422), Expect = 1e-42
Identities = 122/396 (30%), Positives = 168/396 (42%), Gaps = 40/396 (10%)
Query: 192 KADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSI 250
+A +SK D+DEC + C C NT S++C C G D CKD+DEC
Sbjct: 19 RAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECER 76
Query: 251 TSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHC 310
C N G Y+C C +G+ + + CQ SCVN GSY C
Sbjct: 77 EDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYEC 136
Query: 311 TCREGWHLRADGRSCRDIDE---CAGGARPCGGGQCRNTV-GSYTCTCTDGLVPSA---- 362
CREG+ L + +C E C C CR T G C C G +
Sbjct: 137 HCREGFFLSDNQHTCIQRPEGMNCMNKNHGCAH-ICRETPKGGIACECRPGFELTKNQRD 195
Query: 363 ---------AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIG 412
G + TC D ++ I + + + ++ G S CH+
Sbjct: 196 CKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAAI 255
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--DG 470
C CP G+ ++P++ C D DEC L C C N GSF+C C+ G++ +
Sbjct: 256 GVHCTCPVGFMLQPDR-KTCKDIDECRLNNGGCDHI--CRNTVGSFECSCKKGYKLLINE 312
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
C+D+DEC + H C NT GSF+CLC GY YG+ C D+DEC+
Sbjct: 313 RNCQDIDECSFDRTCDH---ICVNTPGSFQCLCHRGYLL--YGIT------HCGDVDECS 361
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAA-DGRSC 565
+ C G C NTPG Y+C C G R +G+ C
Sbjct: 362 INRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDC 396
Score = 127 bits (306), Expect = 1e-28
Identities = 71/208 (34%), Positives = 97/208 (46%), Gaps = 9/208 (4%)
Query: 127 GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCH 186
G C H C + G C C + + TC++ C + +G C D CH+ C
Sbjct: 205 GGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTCIET--CAVNNGGC-DSKCHDAAIGVHCT 260
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C G+ K C DIDEC N+ C C NT GSF C C G +L + +C+DID
Sbjct: 261 CPVGFMLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDID 319
Query: 247 ECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPG 306
ECS C + C N G++QC+C GY + +H C+ C+NTPG
Sbjct: 320 ECSFDR-TCDH-ICVNTPGSFQCLCHRGYLLYGI-THCGDVDECSINRGGCRFGCINTPG 376
Query: 307 SYHCTCREG-WHLRADGRSCRDIDECAG 333
SY CTC G L +G+ C + +C G
Sbjct: 377 SYQCTCPAGQGRLHWNGKDCTEPLKCQG 404
Score = 125 bits (302), Expect = 4e-28
Identities = 92/326 (28%), Positives = 137/326 (42%), Gaps = 36/326 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE---CEIVDGVCGD 173
++V+ECA G C C N++G + C C G+ HTC+ E C + C
Sbjct: 111 LDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLSDNQHTCIQRPEGMNCMNKNHGCAH 169
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
+G C CRPG++ + C C + C+ C +T RC C
Sbjct: 170 ICRETPKGGIACECRPGFELTKNQRDCKLT--CNYGNGGCQH-TCDDTEQGPRCGCHIKF 226
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L D +C I+ C++ +G C + + +G + C C G+ +
Sbjct: 227 VLHTDGKTC--IETCAVNNGGCDSKCHDAAIGVH-CTCPVGFMLQPDRKTCKDIDECRLN 283
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H C NT GS+ C+C++G+ L + R+C+DIDEC+ R C C NT GS+ C
Sbjct: 284 NGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFD-RTC-DHICVNTPGSFQCL 341
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G + C D+DEC S++ C G C NT GS
Sbjct: 342 CHRGYLLYGI---THCGDVDEC----------SINR----------GGCRFG-CINTPGS 377
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECE 439
+ C CP G G CT+ +C+
Sbjct: 378 YQCTCPAGQGRLHWNGKDCTEPLKCQ 403
Score = 105 bits (252), Expect = 4e-22
Identities = 54/137 (39%), Positives = 73/137 (53%), Gaps = 11/137 (8%)
Query: 431 ACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDEC-LTNNGGCHPR 489
A D DEC GT +CH A C N P S++C C+ G+ GDG C+DVDEC +N GC
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGC--V 83
Query: 490 ATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYE 549
C N G++RC C G+ G ++C+D+DECA C+ C N G YE
Sbjct: 84 HDCVNIPGNYRCTCYDGFHLAHDG-------HNCLDVDECAEGNGGCQQS-CVNMMGSYE 135
Query: 550 CDCDVGFTRAADGRSCL 566
C C GF + + +C+
Sbjct: 136 CHCREGFFLSDNQHTCI 152
>AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and
EGF-like domain containing protein 3 protein.
Length = 993
Score = 194 bits (473), Expect = 7e-49
Identities = 131/396 (33%), Positives = 173/396 (43%), Gaps = 45/396 (11%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC C C+N + C C GY D K+ C DV+ECE D DC
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKH--CKDVDECEREDNAGCVHDC 86
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G++ C C G+ C+D+DECA+ + C+ CVN GS+ C C G L+
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLS 145
Query: 237 PDRLSCKDIDE----CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
++ +C E C + C++ E G C C G+ K+
Sbjct: 146 DNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGF--ELTKNQRDCKLTCNY 203
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
CQH+C +T C C + L DG++C I+ CA C +C + C
Sbjct: 204 GNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGC-DSKCHDAATGVHC 260
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
TC G + + TC+DIDEC L I C NT+G
Sbjct: 261 TCPVGFM--LQPDRKTCKDIDEC-------------RLNNGGCDHI--------CRNTVG 297
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
SF C C GY + + C D DEC TCD H C+N PGSFQC C G+ G
Sbjct: 298 SFECSCKKGYKLLINE-RNCQDIDECSFDRTCD-H---ICVNTPGSFQCLCHRGYLLYGI 352
Query: 472 T-CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
T C DVDEC N GGC R C NT GS++C C G
Sbjct: 353 THCGDVDECSINRGGC--RFGCINTPGSYQCTCPAG 386
Score = 173 bits (422), Expect = 1e-42
Identities = 122/397 (30%), Positives = 168/397 (42%), Gaps = 41/397 (10%)
Query: 192 KADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSI 250
+A +SK D+DEC + C C NT S++C C G D CKD+DEC
Sbjct: 19 RAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECER 76
Query: 251 TSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHC 310
C N G Y+C C +G+ + + CQ SCVN GSY C
Sbjct: 77 EDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYEC 136
Query: 311 TCREGWHLRADGRSCRDIDE----CAGGARPCGGGQCRNTV-GSYTCTCTDGLVPSA--- 362
CREG+ L + +C E C C CR T G C C G +
Sbjct: 137 HCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH-ICRETPKGGIACECRPGFELTKNQR 195
Query: 363 ----------AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTI 411
G + TC D ++ I + + + ++ G S CH+
Sbjct: 196 DCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAA 255
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--D 469
C CP G+ ++P++ C D DEC L C C N GSF+C C+ G++ +
Sbjct: 256 TGVHCTCPVGFMLQPDR-KTCKDIDECRLNNGGCDHI--CRNTVGSFECSCKKGYKLLIN 312
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
C+D+DEC + H C NT GSF+CLC GY YG+ C D+DEC
Sbjct: 313 ERNCQDIDECSFDRTCDH---ICVNTPGSFQCLCHRGYLL--YGIT------HCGDVDEC 361
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAA-DGRSC 565
+ + C G C NTPG Y+C C G R +G+ C
Sbjct: 362 SINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDC 397
Score = 128 bits (308), Expect = 7e-29
Identities = 71/208 (34%), Positives = 97/208 (46%), Gaps = 9/208 (4%)
Query: 127 GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCH 186
G C H C + G C C + + TC++ C + +G C D CH+ C
Sbjct: 206 GGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTCIET--CAVNNGGC-DSKCHDAATGVHCT 261
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C G+ K C DIDEC N+ C C NT GSF C C G +L + +C+DID
Sbjct: 262 CPVGFMLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDID 320
Query: 247 ECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPG 306
ECS C + C N G++QC+C GY + +H C+ C+NTPG
Sbjct: 321 ECSFDR-TCDH-ICVNTPGSFQCLCHRGYLLYGI-THCGDVDECSINRGGCRFGCINTPG 377
Query: 307 SYHCTCREG-WHLRADGRSCRDIDECAG 333
SY CTC G L +G+ C + +C G
Sbjct: 378 SYQCTCPAGQGRLHWNGKDCTEPLKCQG 405
Score = 124 bits (299), Expect = 8e-28
Identities = 92/327 (28%), Positives = 135/327 (41%), Gaps = 37/327 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE----CEIVDGVCG 172
++V+ECA G C C N++G + C C G+ HTC+ E C + C
Sbjct: 111 LDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCA 169
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
+G C CRPG++ + C C + C+ C +T RC C
Sbjct: 170 HICRETPKGGIACECRPGFELTKNQRDCKLT--CNYGNGGCQH-TCDDTEQGPRCGCHIK 226
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
L D +C I+ C++ +G C + C + C C G+ +
Sbjct: 227 FVLHTDGKTC--IETCAVNNGGCDS-KCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRL 283
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C H C NT GS+ C+C++G+ L + R+C+DIDEC+ R C C NT GS+ C
Sbjct: 284 NNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFD-RTC-DHICVNTPGSFQC 341
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C G + C D+DEC S++ C G C NT G
Sbjct: 342 LCHRGYLLYGI---THCGDVDEC----------SINR----------GGCRFG-CINTPG 377
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECE 439
S+ C CP G G CT+ +C+
Sbjct: 378 SYQCTCPAGQGRLHWNGKDCTEPLKCQ 404
Score = 105 bits (252), Expect = 4e-22
Identities = 54/137 (39%), Positives = 73/137 (53%), Gaps = 11/137 (8%)
Query: 431 ACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDEC-LTNNGGCHPR 489
A D DEC GT +CH A C N P S++C C+ G+ GDG C+DVDEC +N GC
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGC--V 83
Query: 490 ATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYE 549
C N G++RC C G+ G ++C+D+DECA C+ C N G YE
Sbjct: 84 HDCVNIPGNYRCTCYDGFHLAHDG-------HNCLDVDECAEGNGGCQQS-CVNMMGSYE 135
Query: 550 CDCDVGFTRAADGRSCL 566
C C GF + + +C+
Sbjct: 136 CHCREGFFLSDNQHTCI 152
>AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens
cDNA FLJ41044 fis, clone NT2RP7000466, highly similar
to Mus musculus CUB domain and EGF-like repeat
containing 1 (Cegf1). ).
Length = 971
Score = 194 bits (473), Expect = 7e-49
Identities = 136/427 (31%), Positives = 195/427 (45%), Gaps = 48/427 (11%)
Query: 160 DVNEC-EIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-- 216
DV+EC + +D D C NT S+ C C+PGY+ + + C DIDEC + GG
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGE--GRQCEDIDECGNE---LNGGCV 99
Query: 217 -RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+N G++RC C G LA D +C D+DEC +G C + C N MG+Y+C C EG+
Sbjct: 100 HDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGF 158
Query: 276 ----AQSTVKSHXXXXXXXXXXXXRCQHSCVNTP-GSYHCTCREGWHLRADGRSCRDIDE 330
Q T C H C P GS C CR G+ L + R C I
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILT 216
Query: 331 CAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
C G C C +T C+C G +C + ++ ++ SV +
Sbjct: 217 CNHGNGGC-QHSCDDTADGPECSCHPQYKMHTDGR--SCLEREDTVLEVTESNTTSVVDG 273
Query: 391 QKSVDPQ-IPELCGAG------SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECEL--G 441
K V + + E C +C +T C CP G++++ + G C D DEC+ G
Sbjct: 274 DKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLD-GKTCKDIDECQTRNG 332
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSF 499
CD H C N+ GSF C C+ G++ D +C+DVDEC + H +C N G+F
Sbjct: 333 GCD-H---FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH---SCINHPGTF 385
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRA 559
C C+ GY G+ C D +EC+ + C+ C NT G YEC C G+
Sbjct: 386 ACACNRGYTLYGF--------THCGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKLH 436
Query: 560 ADGRSCL 566
+ + C+
Sbjct: 437 WNKKDCV 443
Score = 186 bits (454), Expect = 1e-46
Identities = 127/412 (30%), Positives = 184/412 (44%), Gaps = 39/412 (9%)
Query: 116 QMEVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC-EIVDGVCGD 173
Q +V+ECA C C+N + C C PGY+ + + C D++EC ++G C
Sbjct: 43 QEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNELNGGCVH 100
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
DC N G++ C C G+ C+D+DEC +N+ C+ CVN GS+ C C G
Sbjct: 101 -DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQ-HTCVNVMGSYECCCKEGF 158
Query: 234 ELAPDRLSCKDIDE----CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
L+ ++ +C E C CS+ E G+ C C G+ K+
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGF--ELAKNQRDCILT 216
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-------RDIDECAGGARPCGGGQ 342
CQHSC +T C+C + + DGRSC ++ E + G +
Sbjct: 217 CNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKR 276
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDID---ECADLISTIIMMSVDELQKSVDPQIP 399
+ + TC +G G TC+D C+ + + + + K +D
Sbjct: 277 VKRRLLMETCAVNNG------GCDRTCKDTSTGVHCSCPVGFTLQLD-GKTCKDIDECQT 329
Query: 400 ELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLPGS 457
G C N +GSF C C G+ + ++ +C D DEC L TCD H CIN PG+
Sbjct: 330 RNGGCDHFCKNIVGSFDCGCKKGFKLLTDE-KSCQDVDECSLDRTCD-H---SCINHPGT 384
Query: 458 FQCRCRDGWRGDGAT-CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
F C C G+ G T C D +EC NNGGC + C NT GS+ C C GYK
Sbjct: 385 FACACNRGYTLYGFTHCGDTNECSINNGGC--QQVCVNTVGSYECQCHPGYK 434
Score = 112 bits (269), Expect = 4e-24
Identities = 58/165 (35%), Positives = 77/165 (46%), Gaps = 5/165 (3%)
Query: 164 CEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAG 223
C + +G C D C +T C C G+ K C DIDEC + C C N G
Sbjct: 286 CAVNNGGC-DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC-DHFCKNIVG 343
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSH 283
SF C C G +L D SC+D+DECS+ C + +C N GT+ C C+ GY +H
Sbjct: 344 SFDCGCKKGFKLLTDEKSCQDVDECSL-DRTCDH-SCINHPGTFACACNRGYTLYGF-TH 400
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDI 328
CQ CVNT GSY C C G+ L + + C ++
Sbjct: 401 CGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEV 445
Score = 106 bits (255), Expect = 2e-22
Identities = 56/148 (37%), Positives = 79/148 (53%), Gaps = 14/148 (9%)
Query: 423 SVKPEQGPAC---TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDEC 479
+V P +G A D DEC G DCH A C N P S++C C+ G++G+G CED+DEC
Sbjct: 31 AVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDEC 90
Query: 480 LTN-NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN 538
NGGC C N G++RC C G+ G ++C+D+DEC + C++
Sbjct: 91 GNELNGGC--VHDCLNIPGNYRCTCFDGFMLAHDG-------HNCLDVDECLENNGGCQH 141
Query: 539 GHCSNTPGGYECDCDVGFTRAADGRSCL 566
C N G YEC C GF + + +C+
Sbjct: 142 -TCVNVMGSYECCCKEGFFLSDNQHTCI 168
Score = 94.3 bits (224), Expect = 1e-18
Identities = 46/128 (35%), Positives = 71/128 (55%), Gaps = 5/128 (3%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC G C H C+N++G F C C G++ + +C DV+EC + D C D C
Sbjct: 323 DIDECQTRNGGCDHF-CKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSL-DRTC-DHSCI 379
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G+F C C GY F+ C D +EC+ N+ C+ CVNT GS+ C+C G +L
Sbjct: 380 NHPGTFACACNRGYTLYGFTH-CGDTNECSINNGGCQ-QVCVNTVGSYECQCHPGYKLHW 437
Query: 238 DRLSCKDI 245
++ C ++
Sbjct: 438 NKKDCVEV 445
>AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein.
Length = 999
Score = 194 bits (473), Expect = 7e-49
Identities = 136/427 (31%), Positives = 195/427 (45%), Gaps = 48/427 (11%)
Query: 160 DVNEC-EIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-- 216
DV+EC + +D D C NT S+ C C+PGY+ + + C DIDEC + GG
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGE--GRQCEDIDECGNE---LNGGCV 99
Query: 217 -RCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+N G++RC C G LA D +C D+DEC +G C + C N MG+Y+C C EG+
Sbjct: 100 HDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGF 158
Query: 276 ----AQSTVKSHXXXXXXXXXXXXRCQHSCVNTP-GSYHCTCREGWHLRADGRSCRDIDE 330
Q T C H C P GS C CR G+ L + R C I
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILT 216
Query: 331 CAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
C G C C +T C+C G +C + ++ ++ SV +
Sbjct: 217 CNHGNGGC-QHSCDDTADGPECSCHPQYKMHTDGR--SCLEREDTVLEVTESNTTSVVDG 273
Query: 391 QKSVDPQ-IPELCGAG------SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECEL--G 441
K V + + E C +C +T C CP G++++ + G C D DEC+ G
Sbjct: 274 DKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLD-GKTCKDIDECQTRNG 332
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSF 499
CD H C N+ GSF C C+ G++ D +C+DVDEC + H +C N G+F
Sbjct: 333 GCD-H---FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH---SCINHPGTF 385
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRA 559
C C+ GY G+ C D +EC+ + C+ C NT G YEC C G+
Sbjct: 386 ACACNRGYTLYGF--------THCGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKLH 436
Query: 560 ADGRSCL 566
+ + C+
Sbjct: 437 WNKKDCV 443
Score = 186 bits (454), Expect = 1e-46
Identities = 127/412 (30%), Positives = 184/412 (44%), Gaps = 39/412 (9%)
Query: 116 QMEVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC-EIVDGVCGD 173
Q +V+ECA C C+N + C C PGY+ + + C D++EC ++G C
Sbjct: 43 QEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNELNGGCVH 100
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
DC N G++ C C G+ C+D+DEC +N+ C+ CVN GS+ C C G
Sbjct: 101 -DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQ-HTCVNVMGSYECCCKEGF 158
Query: 234 ELAPDRLSCKDIDE----CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
L+ ++ +C E C CS+ E G+ C C G+ K+
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGF--ELAKNQRDCILT 216
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-------RDIDECAGGARPCGGGQ 342
CQHSC +T C+C + + DGRSC ++ E + G +
Sbjct: 217 CNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKR 276
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDID---ECADLISTIIMMSVDELQKSVDPQIP 399
+ + TC +G G TC+D C+ + + + + K +D
Sbjct: 277 VKRRLLMETCAVNNG------GCDRTCKDTSTGVHCSCPVGFTLQLD-GKTCKDIDECQT 329
Query: 400 ELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLPGS 457
G C N +GSF C C G+ + ++ +C D DEC L TCD H CIN PG+
Sbjct: 330 RNGGCDHFCKNIVGSFDCGCKKGFKLLTDE-KSCQDVDECSLDRTCD-H---SCINHPGT 384
Query: 458 FQCRCRDGWRGDGAT-CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
F C C G+ G T C D +EC NNGGC + C NT GS+ C C GYK
Sbjct: 385 FACACNRGYTLYGFTHCGDTNECSINNGGC--QQVCVNTVGSYECQCHPGYK 434
Score = 112 bits (269), Expect = 4e-24
Identities = 58/165 (35%), Positives = 77/165 (46%), Gaps = 5/165 (3%)
Query: 164 CEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAG 223
C + +G C D C +T C C G+ K C DIDEC + C C N G
Sbjct: 286 CAVNNGGC-DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC-DHFCKNIVG 343
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSH 283
SF C C G +L D SC+D+DECS+ C + +C N GT+ C C+ GY +H
Sbjct: 344 SFDCGCKKGFKLLTDEKSCQDVDECSL-DRTCDH-SCINHPGTFACACNRGYTLYGF-TH 400
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDI 328
CQ CVNT GSY C C G+ L + + C ++
Sbjct: 401 CGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEV 445
Score = 111 bits (267), Expect = 6e-24
Identities = 69/209 (33%), Positives = 90/209 (43%), Gaps = 10/209 (4%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
CA G C C++ G C C G+ TC D++EC+ +G C D C N G
Sbjct: 286 CAVNNGGCDR-TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC-DHFCKNIVG 343
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
SF C C+ G+K K C D+DEC+ D C C+N G+F C C G L
Sbjct: 344 SFDCGCKKGFKLLTDEKSCQDVDECS-LDRTC-DHSCINHPGTFACACNRGYTLY-GFTH 400
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSH--XXXXXXXXXXXXRCQH 299
C D +ECSI +G C C N +G+Y+C C GY K R
Sbjct: 401 CGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSVSPRVSL 459
Query: 300 SCVNTPGSYHC--TCREGWHLRADGRSCR 326
C + G C C G HL +D + R
Sbjct: 460 HCGKSGGGDGCFLRCHSGIHLSSDVTTIR 488
Score = 106 bits (255), Expect = 2e-22
Identities = 56/148 (37%), Positives = 79/148 (53%), Gaps = 14/148 (9%)
Query: 423 SVKPEQGPAC---TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDEC 479
+V P +G A D DEC G DCH A C N P S++C C+ G++G+G CED+DEC
Sbjct: 31 AVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDEC 90
Query: 480 LTN-NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN 538
NGGC C N G++RC C G+ G ++C+D+DEC + C++
Sbjct: 91 GNELNGGC--VHDCLNIPGNYRCTCFDGFMLAHDG-------HNCLDVDECLENNGGCQH 141
Query: 539 GHCSNTPGGYECDCDVGFTRAADGRSCL 566
C N G YEC C GF + + +C+
Sbjct: 142 -TCVNVMGSYECCCKEGFFLSDNQHTCI 168
Score = 94.3 bits (224), Expect = 1e-18
Identities = 46/128 (35%), Positives = 71/128 (55%), Gaps = 5/128 (3%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC G C H C+N++G F C C G++ + +C DV+EC + D C D C
Sbjct: 323 DIDECQTRNGGCDHF-CKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSL-DRTC-DHSCI 379
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
N G+F C C GY F+ C D +EC+ N+ C+ CVNT GS+ C+C G +L
Sbjct: 380 NHPGTFACACNRGYTLYGFTH-CGDTNECSINNGGCQ-QVCVNTVGSYECQCHPGYKLHW 437
Query: 238 DRLSCKDI 245
++ C ++
Sbjct: 438 NKKDCVEV 445
>AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing
protein protein.
Length = 993
Score = 194 bits (473), Expect = 7e-49
Identities = 131/396 (33%), Positives = 173/396 (43%), Gaps = 45/396 (11%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC C C+N + C C GY D K+ C DV+ECE D DC
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKH--CKDVDECEREDNAGCVHDC 86
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G++ C C G+ C+D+DECA+ + C+ CVN GS+ C C G L+
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLS 145
Query: 237 PDRLSCKDIDE----CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
++ +C E C + C++ E G C C G+ K+
Sbjct: 146 DNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGF--ELTKNQRDCKLTCNY 203
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
CQH+C +T C C + L DG++C I+ CA C +C + C
Sbjct: 204 GNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGC-DSKCHDAATGVHC 260
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
TC G + + TC+DIDEC L I C NT+G
Sbjct: 261 TCPVGFM--LQPDRKTCKDIDEC-------------RLNNGGCDHI--------CRNTVG 297
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
SF C C GY + + C D DEC TCD H C+N PGSFQC C G+ G
Sbjct: 298 SFECSCKKGYKLLINE-RNCQDIDECSFDRTCD-H---ICVNTPGSFQCLCHRGYLLYGI 352
Query: 472 T-CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
T C DVDEC N GGC R C NT GS++C C G
Sbjct: 353 THCGDVDECSINRGGC--RFGCINTPGSYQCTCPAG 386
Score = 173 bits (422), Expect = 1e-42
Identities = 122/397 (30%), Positives = 168/397 (42%), Gaps = 41/397 (10%)
Query: 192 KADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSI 250
+A +SK D+DEC + C C NT S++C C G D CKD+DEC
Sbjct: 19 RAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECER 76
Query: 251 TSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHC 310
C N G Y+C C +G+ + + CQ SCVN GSY C
Sbjct: 77 EDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYEC 136
Query: 311 TCREGWHLRADGRSCRDIDE----CAGGARPCGGGQCRNTV-GSYTCTCTDGLVPSA--- 362
CREG+ L + +C E C C CR T G C C G +
Sbjct: 137 HCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH-ICRETPKGGIACECRPGFELTKNQR 195
Query: 363 ----------AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTI 411
G + TC D ++ I + + + ++ G S CH+
Sbjct: 196 DCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAA 255
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--D 469
C CP G+ ++P++ C D DEC L C C N GSF+C C+ G++ +
Sbjct: 256 TGVHCTCPVGFMLQPDR-KTCKDIDECRLNNGGCDHI--CRNTVGSFECSCKKGYKLLIN 312
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
C+D+DEC + H C NT GSF+CLC GY YG+ C D+DEC
Sbjct: 313 ERNCQDIDECSFDRTCDH---ICVNTPGSFQCLCHRGYLL--YGIT------HCGDVDEC 361
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAA-DGRSC 565
+ + C G C NTPG Y+C C G R +G+ C
Sbjct: 362 SINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDC 397
Score = 128 bits (308), Expect = 7e-29
Identities = 71/208 (34%), Positives = 97/208 (46%), Gaps = 9/208 (4%)
Query: 127 GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCH 186
G C H C + G C C + + TC++ C + +G C D CH+ C
Sbjct: 206 GGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTCIET--CAVNNGGC-DSKCHDAATGVHCT 261
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C G+ K C DIDEC N+ C C NT GSF C C G +L + +C+DID
Sbjct: 262 CPVGFMLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDID 320
Query: 247 ECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPG 306
ECS C + C N G++QC+C GY + +H C+ C+NTPG
Sbjct: 321 ECSFDR-TCDH-ICVNTPGSFQCLCHRGYLLYGI-THCGDVDECSINRGGCRFGCINTPG 377
Query: 307 SYHCTCREG-WHLRADGRSCRDIDECAG 333
SY CTC G L +G+ C + +C G
Sbjct: 378 SYQCTCPAGQGRLHWNGKDCTEPLKCQG 405
Score = 124 bits (299), Expect = 8e-28
Identities = 92/327 (28%), Positives = 135/327 (41%), Gaps = 37/327 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE----CEIVDGVCG 172
++V+ECA G C C N++G + C C G+ HTC+ E C + C
Sbjct: 111 LDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCA 169
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
+G C CRPG++ + C C + C+ C +T RC C
Sbjct: 170 HICRETPKGGIACECRPGFELTKNQRDCKLT--CNYGNGGCQH-TCDDTEQGPRCGCHIK 226
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
L D +C I+ C++ +G C + C + C C G+ +
Sbjct: 227 FVLHTDGKTC--IETCAVNNGGCDS-KCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRL 283
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C H C NT GS+ C+C++G+ L + R+C+DIDEC+ R C C NT GS+ C
Sbjct: 284 NNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFD-RTC-DHICVNTPGSFQC 341
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C G + C D+DEC S++ C G C NT G
Sbjct: 342 LCHRGYLLYGI---THCGDVDEC----------SINR----------GGCRFG-CINTPG 377
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECE 439
S+ C CP G G CT+ +C+
Sbjct: 378 SYQCTCPAGQGRLHWNGKDCTEPLKCQ 404
Score = 105 bits (252), Expect = 4e-22
Identities = 54/137 (39%), Positives = 73/137 (53%), Gaps = 11/137 (8%)
Query: 431 ACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDEC-LTNNGGCHPR 489
A D DEC GT +CH A C N P S++C C+ G+ GDG C+DVDEC +N GC
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGC--V 83
Query: 490 ATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYE 549
C N G++RC C G+ G ++C+D+DECA C+ C N G YE
Sbjct: 84 HDCVNIPGNYRCTCYDGFHLAHDG-------HNCLDVDECAEGNGGCQQS-CVNMMGSYE 135
Query: 550 CDCDVGFTRAADGRSCL 566
C C GF + + +C+
Sbjct: 136 CHCREGFFLSDNQHTCI 152
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 192 bits (468), Expect = 3e-48
Identities = 137/448 (30%), Positives = 200/448 (44%), Gaps = 51/448 (11%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHN 178
+ECAA C H C N +G + C C G + TC D++EC + C G DC N
Sbjct: 5109 DECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDN 5166
Query: 179 TEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
T GS+ C C G++ C DI+EC ++ C RC N GSF C C G +L
Sbjct: 5167 TIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCFNAIGSFHCGCEPGYQLK 5224
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXX 293
+ C D++EC +C + C+N G Y+C+ C G ++
Sbjct: 5225 GRK--CMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE-NGTCIDIDECKDG 5279
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C+++ C NT GSY C C G+ + GR C DI+EC +PC QC NT GS+
Sbjct: 5280 THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-AHQCSNTPGSFK 5338
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADL---ISTIIMMSVDELQKSVDP-----QIPELCG 403
C C G G +C ++ + S+ + ++ + P Q L
Sbjct: 5339 CICPPG--QHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYS 5396
Query: 404 AGSCHNTIGSFVCQ--------CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP 455
+ S + + + + CP+G + C D DECE T C +C N
Sbjct: 5397 SYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD---TCVDIDECE-NTDACQ--HECKNTF 5450
Query: 456 GSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGD 510
GS+QC C G++ +G TC+D+DECL N C P C N GS++C+ C Y+ D
Sbjct: 5451 GSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Query: 511 GYGLRTVCCVYSCVDID-ECANDPTLCE 537
+ C+ +C D ECA P E
Sbjct: 5511 PV---SGFCLKNCPPNDLECALSPYALE 5535
Score = 186 bits (454), Expect = 1e-46
Identities = 109/277 (39%), Positives = 139/277 (50%), Gaps = 43/277 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C HSC N G+Y+C+C +G + ADGR+C+DIDECA G C GQ C NT+GSY C
Sbjct: 5117 CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVR 5176
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G ++ G +CQDI+EC Q+S P C C N IGS
Sbjct: 5177 CGSGFRRTSDGL--SCQDINEC---------------QES-SP-----CHQ-RCFNAIGS 5212
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC--RCRDGW-RGDG 470
F C C GY +K G C D +EC C P C N G ++C C +G + +
Sbjct: 5213 FHCGCEPGYQLK---GRKCMDVNECRQNVC--RPDQHCKNTRGGYKCIDLCPNGMTKAEN 5267
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
TC D+DEC C C NT GS+RC+C GY+ G G C+DI+EC
Sbjct: 5268 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG-------RPCMDINECE 5320
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
P C + CSNTPG ++C C G DG+SC G
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAG 5356
Score = 161 bits (390), Expect = 8e-39
Identities = 129/420 (30%), Positives = 179/420 (42%), Gaps = 66/420 (15%)
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
++G + C G+ D C D DECA + C N G++ C C G+ +A D
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAAD 5141
Query: 239 RLSCKDIDECSITSGICSNGA-CENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXX 295
+C+DIDEC++ C G C+N +G+Y+CV C G+ + T
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSCQDINECQESS 5200
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG-ARPCGGGQCRNTVGSYTC-- 352
C C N GS+HC C G+ L+ GR C D++EC RP C+NT G Y C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRP--DQHCKNTRGGYKCID 5256
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G+ + G TC DIDEC D + + + QI C NT G
Sbjct: 5257 LCPNGMTKAENG---TCIDIDECKD--------GTHQCRYN---QI--------CENTRG 5294
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
S+ C CP GY G C D +ECE C A C N PGSF+C C G GDG
Sbjct: 5295 SYRCVCPRGYR-SQGVGRPCMDINECEQVPKPC--AHQCSNTPGSFKCICPPGQHLLGDG 5351
Query: 471 ATCEDVDECLTNNGGCHPRATCAN--------------TDGSFRCLCDTGYKGDGYGL-R 515
+C + E L N G + A S + Y+ L R
Sbjct: 5352 KSCAGL-ERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSR 5410
Query: 516 TVCCV-YSCVDIDECANDPTL----CEN-----GHCSNTPGGYECDCDVGFTRAADGRSC 565
T + +C + E ++D + CEN C NT G Y+C C G+ +G++C
Sbjct: 5411 TRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTC 5470
Score = 145 bits (351), Expect = 4e-34
Identities = 80/219 (36%), Positives = 110/219 (50%), Gaps = 14/219 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+++ECA C G+ C N +G + C C G+ + S +C D+NEC+ C
Sbjct: 5147 DIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR 5205
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCE--CGH 231
C N GSF C C PGY+ + C+D++EC N +CR + C NT G ++C C +
Sbjct: 5206 -CFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 232 GMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
GM A + +C DIDEC + C N CEN G+Y+CVC GY V
Sbjct: 5261 GMTKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC 5319
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDID 329
C H C NTPGS+ C C G HL DG+SC ++
Sbjct: 5320 EQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE 5358
Score = 64.1 bits (149), Expect = 1e-09
Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
++++EC C H C+N G + C C PGY+ TC D++EC + CG
Sbjct: 5431 VDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 176 CHNTEGSFTC---HCRPGYKADDFSKICVDIDECADNDALC 213
C N GS+ C C P Y+ D S C + C ND C
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFC--LKNCPPNDLEC 5527
Score = 60.9 bits (141), Expect = 1e-08
Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 15/197 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M++NEC P C H +C N G F C C PG H D C ++ + G
Sbjct: 5314 MDINECEQVPKPCAH-QCSNTPGSFKCICPPG------QHLLGDGKSCAGLERLPNYGTQ 5366
Query: 177 HNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+++ + R Y+ + + R T + R C G E
Sbjct: 5367 YSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTS-LSRTRRTIRKTCPEGSEA 5425
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C DIDEC T C + C+N G+YQC+C GY +
Sbjct: 5426 SHD--TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNV 5481
Query: 296 RC--QHSCVNTPGSYHC 310
C C N GSY C
Sbjct: 5482 HCGPNRMCFNMRGSYQC 5498
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 192 bits (468), Expect = 3e-48
Identities = 137/448 (30%), Positives = 200/448 (44%), Gaps = 51/448 (11%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHN 178
+ECAA C H C N +G + C C G + TC D++EC + C G DC N
Sbjct: 5109 DECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDN 5166
Query: 179 TEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
T GS+ C C G++ C DI+EC ++ C RC N GSF C C G +L
Sbjct: 5167 TIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCFNAIGSFHCGCEPGYQLK 5224
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXX 293
+ C D++EC +C + C+N G Y+C+ C G ++
Sbjct: 5225 GRK--CMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE-NGTCIDIDECKDG 5279
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C+++ C NT GSY C C G+ + GR C DI+EC +PC QC NT GS+
Sbjct: 5280 THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-AHQCSNTPGSFK 5338
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADL---ISTIIMMSVDELQKSVDP-----QIPELCG 403
C C G G +C ++ + S+ + ++ + P Q L
Sbjct: 5339 CICPPG--QHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYS 5396
Query: 404 AGSCHNTIGSFVCQ--------CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP 455
+ S + + + + CP+G + C D DECE T C +C N
Sbjct: 5397 SYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD---TCVDIDECE-NTDACQ--HECKNTF 5450
Query: 456 GSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGD 510
GS+QC C G++ +G TC+D+DECL N C P C N GS++C+ C Y+ D
Sbjct: 5451 GSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Query: 511 GYGLRTVCCVYSCVDID-ECANDPTLCE 537
+ C+ +C D ECA P E
Sbjct: 5511 PV---SGFCLKNCPPNDLECALSPYALE 5535
Score = 186 bits (454), Expect = 1e-46
Identities = 109/277 (39%), Positives = 139/277 (50%), Gaps = 43/277 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C HSC N G+Y+C+C +G + ADGR+C+DIDECA G C GQ C NT+GSY C
Sbjct: 5117 CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVR 5176
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G ++ G +CQDI+EC Q+S P C C N IGS
Sbjct: 5177 CGSGFRRTSDGL--SCQDINEC---------------QES-SP-----CHQ-RCFNAIGS 5212
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC--RCRDGW-RGDG 470
F C C GY +K G C D +EC C P C N G ++C C +G + +
Sbjct: 5213 FHCGCEPGYQLK---GRKCMDVNECRQNVC--RPDQHCKNTRGGYKCIDLCPNGMTKAEN 5267
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
TC D+DEC C C NT GS+RC+C GY+ G G C+DI+EC
Sbjct: 5268 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG-------RPCMDINECE 5320
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
P C + CSNTPG ++C C G DG+SC G
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAG 5356
Score = 161 bits (390), Expect = 8e-39
Identities = 129/420 (30%), Positives = 179/420 (42%), Gaps = 66/420 (15%)
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
++G + C G+ D C D DECA + C N G++ C C G+ +A D
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAAD 5141
Query: 239 RLSCKDIDECSITSGICSNGA-CENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXX 295
+C+DIDEC++ C G C+N +G+Y+CV C G+ + T
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSCQDINECQESS 5200
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG-ARPCGGGQCRNTVGSYTC-- 352
C C N GS+HC C G+ L+ GR C D++EC RP C+NT G Y C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRP--DQHCKNTRGGYKCID 5256
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G+ + G TC DIDEC D + + + QI C NT G
Sbjct: 5257 LCPNGMTKAENG---TCIDIDECKD--------GTHQCRYN---QI--------CENTRG 5294
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
S+ C CP GY G C D +ECE C A C N PGSF+C C G GDG
Sbjct: 5295 SYRCVCPRGYR-SQGVGRPCMDINECEQVPKPC--AHQCSNTPGSFKCICPPGQHLLGDG 5351
Query: 471 ATCEDVDECLTNNGGCHPRATCAN--------------TDGSFRCLCDTGYKGDGYGL-R 515
+C + E L N G + A S + Y+ L R
Sbjct: 5352 KSCAGL-ERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSR 5410
Query: 516 TVCCV-YSCVDIDECANDPTL----CEN-----GHCSNTPGGYECDCDVGFTRAADGRSC 565
T + +C + E ++D + CEN C NT G Y+C C G+ +G++C
Sbjct: 5411 TRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTC 5470
Score = 145 bits (351), Expect = 4e-34
Identities = 80/219 (36%), Positives = 110/219 (50%), Gaps = 14/219 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+++ECA C G+ C N +G + C C G+ + S +C D+NEC+ C
Sbjct: 5147 DIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR 5205
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCE--CGH 231
C N GSF C C PGY+ + C+D++EC N +CR + C NT G ++C C +
Sbjct: 5206 -CFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 232 GMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
GM A + +C DIDEC + C N CEN G+Y+CVC GY V
Sbjct: 5261 GMTKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC 5319
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDID 329
C H C NTPGS+ C C G HL DG+SC ++
Sbjct: 5320 EQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE 5358
Score = 64.1 bits (149), Expect = 1e-09
Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
++++EC C H C+N G + C C PGY+ TC D++EC + CG
Sbjct: 5431 VDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 176 CHNTEGSFTC---HCRPGYKADDFSKICVDIDECADNDALC 213
C N GS+ C C P Y+ D S C + C ND C
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFC--LKNCPPNDLEC 5527
Score = 60.9 bits (141), Expect = 1e-08
Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 15/197 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M++NEC P C H +C N G F C C PG H D C ++ + G
Sbjct: 5314 MDINECEQVPKPCAH-QCSNTPGSFKCICPPG------QHLLGDGKSCAGLERLPNYGTQ 5366
Query: 177 HNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+++ + R Y+ + + R T + R C G E
Sbjct: 5367 YSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTS-LSRTRRTIRKTCPEGSEA 5425
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C DIDEC T C + C+N G+YQC+C GY +
Sbjct: 5426 SHD--TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNV 5481
Query: 296 RC--QHSCVNTPGSYHC 310
C C N GSY C
Sbjct: 5482 HCGPNRMCFNMRGSYQC 5498
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 192 bits (468), Expect = 3e-48
Identities = 137/448 (30%), Positives = 200/448 (44%), Gaps = 51/448 (11%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHN 178
+ECAA C H C N +G + C C G + TC D++EC + C G DC N
Sbjct: 5109 DECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDN 5166
Query: 179 TEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
T GS+ C C G++ C DI+EC ++ C RC N GSF C C G +L
Sbjct: 5167 TIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCFNAIGSFHCGCEPGYQLK 5224
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXX 293
+ C D++EC +C + C+N G Y+C+ C G ++
Sbjct: 5225 GRK--CMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE-NGTCIDIDECKDG 5279
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C+++ C NT GSY C C G+ + GR C DI+EC +PC QC NT GS+
Sbjct: 5280 THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-AHQCSNTPGSFK 5338
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADL---ISTIIMMSVDELQKSVDP-----QIPELCG 403
C C G G +C ++ + S+ + ++ + P Q L
Sbjct: 5339 CICPPG--QHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYS 5396
Query: 404 AGSCHNTIGSFVCQ--------CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP 455
+ S + + + + CP+G + C D DECE T C +C N
Sbjct: 5397 SYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD---TCVDIDECE-NTDACQ--HECKNTF 5450
Query: 456 GSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGD 510
GS+QC C G++ +G TC+D+DECL N C P C N GS++C+ C Y+ D
Sbjct: 5451 GSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Query: 511 GYGLRTVCCVYSCVDID-ECANDPTLCE 537
+ C+ +C D ECA P E
Sbjct: 5511 PV---SGFCLKNCPPNDLECALSPYALE 5535
Score = 186 bits (454), Expect = 1e-46
Identities = 109/277 (39%), Positives = 139/277 (50%), Gaps = 43/277 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C HSC N G+Y+C+C +G + ADGR+C+DIDECA G C GQ C NT+GSY C
Sbjct: 5117 CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVR 5176
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G ++ G +CQDI+EC Q+S P C C N IGS
Sbjct: 5177 CGSGFRRTSDGL--SCQDINEC---------------QES-SP-----CHQ-RCFNAIGS 5212
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC--RCRDGW-RGDG 470
F C C GY +K G C D +EC C P C N G ++C C +G + +
Sbjct: 5213 FHCGCEPGYQLK---GRKCMDVNECRQNVC--RPDQHCKNTRGGYKCIDLCPNGMTKAEN 5267
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
TC D+DEC C C NT GS+RC+C GY+ G G C+DI+EC
Sbjct: 5268 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG-------RPCMDINECE 5320
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
P C + CSNTPG ++C C G DG+SC G
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAG 5356
Score = 161 bits (390), Expect = 8e-39
Identities = 129/420 (30%), Positives = 179/420 (42%), Gaps = 66/420 (15%)
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
++G + C G+ D C D DECA + C N G++ C C G+ +A D
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAAD 5141
Query: 239 RLSCKDIDECSITSGICSNGA-CENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXX 295
+C+DIDEC++ C G C+N +G+Y+CV C G+ + T
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSCQDINECQESS 5200
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG-ARPCGGGQCRNTVGSYTC-- 352
C C N GS+HC C G+ L+ GR C D++EC RP C+NT G Y C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRP--DQHCKNTRGGYKCID 5256
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G+ + G TC DIDEC D + + + QI C NT G
Sbjct: 5257 LCPNGMTKAENG---TCIDIDECKD--------GTHQCRYN---QI--------CENTRG 5294
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
S+ C CP GY G C D +ECE C A C N PGSF+C C G GDG
Sbjct: 5295 SYRCVCPRGYR-SQGVGRPCMDINECEQVPKPC--AHQCSNTPGSFKCICPPGQHLLGDG 5351
Query: 471 ATCEDVDECLTNNGGCHPRATCAN--------------TDGSFRCLCDTGYKGDGYGL-R 515
+C + E L N G + A S + Y+ L R
Sbjct: 5352 KSCAGL-ERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSR 5410
Query: 516 TVCCV-YSCVDIDECANDPTL----CEN-----GHCSNTPGGYECDCDVGFTRAADGRSC 565
T + +C + E ++D + CEN C NT G Y+C C G+ +G++C
Sbjct: 5411 TRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTC 5470
Score = 145 bits (351), Expect = 4e-34
Identities = 80/219 (36%), Positives = 110/219 (50%), Gaps = 14/219 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+++ECA C G+ C N +G + C C G+ + S +C D+NEC+ C
Sbjct: 5147 DIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR 5205
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCE--CGH 231
C N GSF C C PGY+ + C+D++EC N +CR + C NT G ++C C +
Sbjct: 5206 -CFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 232 GMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
GM A + +C DIDEC + C N CEN G+Y+CVC GY V
Sbjct: 5261 GMTKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC 5319
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDID 329
C H C NTPGS+ C C G HL DG+SC ++
Sbjct: 5320 EQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE 5358
Score = 64.1 bits (149), Expect = 1e-09
Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
++++EC C H C+N G + C C PGY+ TC D++EC + CG
Sbjct: 5431 VDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 176 CHNTEGSFTC---HCRPGYKADDFSKICVDIDECADNDALC 213
C N GS+ C C P Y+ D S C + C ND C
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFC--LKNCPPNDLEC 5527
Score = 60.9 bits (141), Expect = 1e-08
Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 15/197 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M++NEC P C H +C N G F C C PG H D C ++ + G
Sbjct: 5314 MDINECEQVPKPCAH-QCSNTPGSFKCICPPG------QHLLGDGKSCAGLERLPNYGTQ 5366
Query: 177 HNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+++ + R Y+ + + R T + R C G E
Sbjct: 5367 YSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTS-LSRTRRTIRKTCPEGSEA 5425
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C DIDEC T C + C+N G+YQC+C GY +
Sbjct: 5426 SHD--TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNV 5481
Query: 296 RC--QHSCVNTPGSYHC 310
C C N GSY C
Sbjct: 5482 HCGPNRMCFNMRGSYQC 5498
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 192 bits (468), Expect = 3e-48
Identities = 137/448 (30%), Positives = 200/448 (44%), Gaps = 51/448 (11%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHN 178
+ECAA C H C N +G + C C G + TC D++EC + C G DC N
Sbjct: 5109 DECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDN 5166
Query: 179 TEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
T GS+ C C G++ C DI+EC ++ C RC N GSF C C G +L
Sbjct: 5167 TIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCFNAIGSFHCGCEPGYQLK 5224
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXX 293
+ C D++EC +C + C+N G Y+C+ C G ++
Sbjct: 5225 GRK--CMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE-NGTCIDIDECKDG 5279
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C+++ C NT GSY C C G+ + GR C DI+EC +PC QC NT GS+
Sbjct: 5280 THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-AHQCSNTPGSFK 5338
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADL---ISTIIMMSVDELQKSVDP-----QIPELCG 403
C C G G +C ++ + S+ + ++ + P Q L
Sbjct: 5339 CICPPG--QHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYS 5396
Query: 404 AGSCHNTIGSFVCQ--------CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP 455
+ S + + + + CP+G + C D DECE T C +C N
Sbjct: 5397 SYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD---TCVDIDECE-NTDACQ--HECKNTF 5450
Query: 456 GSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGD 510
GS+QC C G++ +G TC+D+DECL N C P C N GS++C+ C Y+ D
Sbjct: 5451 GSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Query: 511 GYGLRTVCCVYSCVDID-ECANDPTLCE 537
+ C+ +C D ECA P E
Sbjct: 5511 PV---SGFCLKNCPPNDLECALSPYALE 5535
Score = 186 bits (454), Expect = 1e-46
Identities = 109/277 (39%), Positives = 139/277 (50%), Gaps = 43/277 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C HSC N G+Y+C+C +G + ADGR+C+DIDECA G C GQ C NT+GSY C
Sbjct: 5117 CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVR 5176
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G ++ G +CQDI+EC Q+S P C C N IGS
Sbjct: 5177 CGSGFRRTSDGL--SCQDINEC---------------QES-SP-----CHQ-RCFNAIGS 5212
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC--RCRDGW-RGDG 470
F C C GY +K G C D +EC C P C N G ++C C +G + +
Sbjct: 5213 FHCGCEPGYQLK---GRKCMDVNECRQNVC--RPDQHCKNTRGGYKCIDLCPNGMTKAEN 5267
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
TC D+DEC C C NT GS+RC+C GY+ G G C+DI+EC
Sbjct: 5268 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG-------RPCMDINECE 5320
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
P C + CSNTPG ++C C G DG+SC G
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAG 5356
Score = 161 bits (390), Expect = 8e-39
Identities = 129/420 (30%), Positives = 179/420 (42%), Gaps = 66/420 (15%)
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
++G + C G+ D C D DECA + C N G++ C C G+ +A D
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAAD 5141
Query: 239 RLSCKDIDECSITSGICSNGA-CENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXX 295
+C+DIDEC++ C G C+N +G+Y+CV C G+ + T
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSCQDINECQESS 5200
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG-ARPCGGGQCRNTVGSYTC-- 352
C C N GS+HC C G+ L+ GR C D++EC RP C+NT G Y C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRP--DQHCKNTRGGYKCID 5256
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G+ + G TC DIDEC D + + + QI C NT G
Sbjct: 5257 LCPNGMTKAENG---TCIDIDECKD--------GTHQCRYN---QI--------CENTRG 5294
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
S+ C CP GY G C D +ECE C A C N PGSF+C C G GDG
Sbjct: 5295 SYRCVCPRGYR-SQGVGRPCMDINECEQVPKPC--AHQCSNTPGSFKCICPPGQHLLGDG 5351
Query: 471 ATCEDVDECLTNNGGCHPRATCAN--------------TDGSFRCLCDTGYKGDGYGL-R 515
+C + E L N G + A S + Y+ L R
Sbjct: 5352 KSCAGL-ERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSR 5410
Query: 516 TVCCV-YSCVDIDECANDPTL----CEN-----GHCSNTPGGYECDCDVGFTRAADGRSC 565
T + +C + E ++D + CEN C NT G Y+C C G+ +G++C
Sbjct: 5411 TRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTC 5470
Score = 145 bits (351), Expect = 4e-34
Identities = 80/219 (36%), Positives = 110/219 (50%), Gaps = 14/219 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+++ECA C G+ C N +G + C C G+ + S +C D+NEC+ C
Sbjct: 5147 DIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR 5205
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCE--CGH 231
C N GSF C C PGY+ + C+D++EC N +CR + C NT G ++C C +
Sbjct: 5206 -CFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 232 GMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
GM A + +C DIDEC + C N CEN G+Y+CVC GY V
Sbjct: 5261 GMTKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC 5319
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDID 329
C H C NTPGS+ C C G HL DG+SC ++
Sbjct: 5320 EQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE 5358
Score = 64.1 bits (149), Expect = 1e-09
Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
++++EC C H C+N G + C C PGY+ TC D++EC + CG
Sbjct: 5431 VDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 176 CHNTEGSFTC---HCRPGYKADDFSKICVDIDECADNDALC 213
C N GS+ C C P Y+ D S C + C ND C
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFC--LKNCPPNDLEC 5527
Score = 60.9 bits (141), Expect = 1e-08
Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 15/197 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M++NEC P C H +C N G F C C PG H D C ++ + G
Sbjct: 5314 MDINECEQVPKPCAH-QCSNTPGSFKCICPPG------QHLLGDGKSCAGLERLPNYGTQ 5366
Query: 177 HNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+++ + R Y+ + + R T + R C G E
Sbjct: 5367 YSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTS-LSRTRRTIRKTCPEGSEA 5425
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C DIDEC T C + C+N G+YQC+C GY +
Sbjct: 5426 SHD--TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNV 5481
Query: 296 RC--QHSCVNTPGSYHC 310
C C N GSY C
Sbjct: 5482 HCGPNRMCFNMRGSYQC 5498
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 192 bits (468), Expect = 3e-48
Identities = 137/448 (30%), Positives = 200/448 (44%), Gaps = 51/448 (11%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHN 178
+ECAA C H C N +G + C C G + TC D++EC + C G DC N
Sbjct: 5109 DECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDN 5166
Query: 179 TEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
T GS+ C C G++ C DI+EC ++ C RC N GSF C C G +L
Sbjct: 5167 TIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCFNAIGSFHCGCEPGYQLK 5224
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXX 293
+ C D++EC +C + C+N G Y+C+ C G ++
Sbjct: 5225 GRK--CMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE-NGTCIDIDECKDG 5279
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C+++ C NT GSY C C G+ + GR C DI+EC +PC QC NT GS+
Sbjct: 5280 THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-AHQCSNTPGSFK 5338
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADL---ISTIIMMSVDELQKSVDP-----QIPELCG 403
C C G G +C ++ + S+ + ++ + P Q L
Sbjct: 5339 CICPPG--QHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYS 5396
Query: 404 AGSCHNTIGSFVCQ--------CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP 455
+ S + + + + CP+G + C D DECE T C +C N
Sbjct: 5397 SYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD---TCVDIDECE-NTDACQ--HECKNTF 5450
Query: 456 GSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGD 510
GS+QC C G++ +G TC+D+DECL N C P C N GS++C+ C Y+ D
Sbjct: 5451 GSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Query: 511 GYGLRTVCCVYSCVDID-ECANDPTLCE 537
+ C+ +C D ECA P E
Sbjct: 5511 PV---SGFCLKNCPPNDLECALSPYALE 5535
Score = 186 bits (454), Expect = 1e-46
Identities = 109/277 (39%), Positives = 139/277 (50%), Gaps = 43/277 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C HSC N G+Y+C+C +G + ADGR+C+DIDECA G C GQ C NT+GSY C
Sbjct: 5117 CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVR 5176
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G ++ G +CQDI+EC Q+S P C C N IGS
Sbjct: 5177 CGSGFRRTSDGL--SCQDINEC---------------QES-SP-----CHQ-RCFNAIGS 5212
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC--RCRDGW-RGDG 470
F C C GY +K G C D +EC C P C N G ++C C +G + +
Sbjct: 5213 FHCGCEPGYQLK---GRKCMDVNECRQNVC--RPDQHCKNTRGGYKCIDLCPNGMTKAEN 5267
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
TC D+DEC C C NT GS+RC+C GY+ G G C+DI+EC
Sbjct: 5268 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG-------RPCMDINECE 5320
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
P C + CSNTPG ++C C G DG+SC G
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAG 5356
Score = 161 bits (390), Expect = 8e-39
Identities = 129/420 (30%), Positives = 179/420 (42%), Gaps = 66/420 (15%)
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
++G + C G+ D C D DECA + C N G++ C C G+ +A D
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAAD 5141
Query: 239 RLSCKDIDECSITSGICSNGA-CENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXX 295
+C+DIDEC++ C G C+N +G+Y+CV C G+ + T
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSCQDINECQESS 5200
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG-ARPCGGGQCRNTVGSYTC-- 352
C C N GS+HC C G+ L+ GR C D++EC RP C+NT G Y C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRP--DQHCKNTRGGYKCID 5256
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G+ + G TC DIDEC D + + + QI C NT G
Sbjct: 5257 LCPNGMTKAENG---TCIDIDECKD--------GTHQCRYN---QI--------CENTRG 5294
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
S+ C CP GY G C D +ECE C A C N PGSF+C C G GDG
Sbjct: 5295 SYRCVCPRGYR-SQGVGRPCMDINECEQVPKPC--AHQCSNTPGSFKCICPPGQHLLGDG 5351
Query: 471 ATCEDVDECLTNNGGCHPRATCAN--------------TDGSFRCLCDTGYKGDGYGL-R 515
+C + E L N G + A S + Y+ L R
Sbjct: 5352 KSCAGL-ERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSR 5410
Query: 516 TVCCV-YSCVDIDECANDPTL----CEN-----GHCSNTPGGYECDCDVGFTRAADGRSC 565
T + +C + E ++D + CEN C NT G Y+C C G+ +G++C
Sbjct: 5411 TRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTC 5470
Score = 145 bits (351), Expect = 4e-34
Identities = 80/219 (36%), Positives = 110/219 (50%), Gaps = 14/219 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+++ECA C G+ C N +G + C C G+ + S +C D+NEC+ C
Sbjct: 5147 DIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR 5205
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCE--CGH 231
C N GSF C C PGY+ + C+D++EC N +CR + C NT G ++C C +
Sbjct: 5206 -CFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 232 GMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
GM A + +C DIDEC + C N CEN G+Y+CVC GY V
Sbjct: 5261 GMTKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC 5319
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDID 329
C H C NTPGS+ C C G HL DG+SC ++
Sbjct: 5320 EQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE 5358
Score = 64.1 bits (149), Expect = 1e-09
Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
++++EC C H C+N G + C C PGY+ TC D++EC + CG
Sbjct: 5431 VDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 176 CHNTEGSFTC---HCRPGYKADDFSKICVDIDECADNDALC 213
C N GS+ C C P Y+ D S C + C ND C
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFC--LKNCPPNDLEC 5527
Score = 60.9 bits (141), Expect = 1e-08
Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 15/197 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M++NEC P C H +C N G F C C PG H D C ++ + G
Sbjct: 5314 MDINECEQVPKPCAH-QCSNTPGSFKCICPPG------QHLLGDGKSCAGLERLPNYGTQ 5366
Query: 177 HNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+++ + R Y+ + + R T + R C G E
Sbjct: 5367 YSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTS-LSRTRRTIRKTCPEGSEA 5425
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C DIDEC T C + C+N G+YQC+C GY +
Sbjct: 5426 SHD--TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNV 5481
Query: 296 RC--QHSCVNTPGSYHC 310
C C N GSY C
Sbjct: 5482 HCGPNRMCFNMRGSYQC 5498
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 192 bits (468), Expect = 3e-48
Identities = 137/448 (30%), Positives = 200/448 (44%), Gaps = 51/448 (11%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHN 178
+ECAA C H C N +G + C C G + TC D++EC + C G DC N
Sbjct: 5109 DECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDN 5166
Query: 179 TEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
T GS+ C C G++ C DI+EC ++ C RC N GSF C C G +L
Sbjct: 5167 TIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCFNAIGSFHCGCEPGYQLK 5224
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXX 293
+ C D++EC +C + C+N G Y+C+ C G ++
Sbjct: 5225 GRK--CMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE-NGTCIDIDECKDG 5279
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C+++ C NT GSY C C G+ + GR C DI+EC +PC QC NT GS+
Sbjct: 5280 THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-AHQCSNTPGSFK 5338
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADL---ISTIIMMSVDELQKSVDP-----QIPELCG 403
C C G G +C ++ + S+ + ++ + P Q L
Sbjct: 5339 CICPPG--QHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYS 5396
Query: 404 AGSCHNTIGSFVCQ--------CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP 455
+ S + + + + CP+G + C D DECE T C +C N
Sbjct: 5397 SYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD---TCVDIDECE-NTDACQ--HECKNTF 5450
Query: 456 GSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGD 510
GS+QC C G++ +G TC+D+DECL N C P C N GS++C+ C Y+ D
Sbjct: 5451 GSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Query: 511 GYGLRTVCCVYSCVDID-ECANDPTLCE 537
+ C+ +C D ECA P E
Sbjct: 5511 PV---SGFCLKNCPPNDLECALSPYALE 5535
Score = 186 bits (454), Expect = 1e-46
Identities = 109/277 (39%), Positives = 139/277 (50%), Gaps = 43/277 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C HSC N G+Y+C+C +G + ADGR+C+DIDECA G C GQ C NT+GSY C
Sbjct: 5117 CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVR 5176
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G ++ G +CQDI+EC Q+S P C C N IGS
Sbjct: 5177 CGSGFRRTSDGL--SCQDINEC---------------QES-SP-----CHQ-RCFNAIGS 5212
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC--RCRDGW-RGDG 470
F C C GY +K G C D +EC C P C N G ++C C +G + +
Sbjct: 5213 FHCGCEPGYQLK---GRKCMDVNECRQNVC--RPDQHCKNTRGGYKCIDLCPNGMTKAEN 5267
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
TC D+DEC C C NT GS+RC+C GY+ G G C+DI+EC
Sbjct: 5268 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG-------RPCMDINECE 5320
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
P C + CSNTPG ++C C G DG+SC G
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAG 5356
Score = 161 bits (390), Expect = 8e-39
Identities = 129/420 (30%), Positives = 179/420 (42%), Gaps = 66/420 (15%)
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
++G + C G+ D C D DECA + C N G++ C C G+ +A D
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAAD 5141
Query: 239 RLSCKDIDECSITSGICSNGA-CENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXX 295
+C+DIDEC++ C G C+N +G+Y+CV C G+ + T
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSCQDINECQESS 5200
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG-ARPCGGGQCRNTVGSYTC-- 352
C C N GS+HC C G+ L+ GR C D++EC RP C+NT G Y C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRP--DQHCKNTRGGYKCID 5256
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G+ + G TC DIDEC D + + + QI C NT G
Sbjct: 5257 LCPNGMTKAENG---TCIDIDECKD--------GTHQCRYN---QI--------CENTRG 5294
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
S+ C CP GY G C D +ECE C A C N PGSF+C C G GDG
Sbjct: 5295 SYRCVCPRGYR-SQGVGRPCMDINECEQVPKPC--AHQCSNTPGSFKCICPPGQHLLGDG 5351
Query: 471 ATCEDVDECLTNNGGCHPRATCAN--------------TDGSFRCLCDTGYKGDGYGL-R 515
+C + E L N G + A S + Y+ L R
Sbjct: 5352 KSCAGL-ERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSR 5410
Query: 516 TVCCV-YSCVDIDECANDPTL----CEN-----GHCSNTPGGYECDCDVGFTRAADGRSC 565
T + +C + E ++D + CEN C NT G Y+C C G+ +G++C
Sbjct: 5411 TRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTC 5470
Score = 145 bits (351), Expect = 4e-34
Identities = 80/219 (36%), Positives = 110/219 (50%), Gaps = 14/219 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+++ECA C G+ C N +G + C C G+ + S +C D+NEC+ C
Sbjct: 5147 DIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR 5205
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCE--CGH 231
C N GSF C C PGY+ + C+D++EC N +CR + C NT G ++C C +
Sbjct: 5206 -CFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 232 GMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
GM A + +C DIDEC + C N CEN G+Y+CVC GY V
Sbjct: 5261 GMTKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC 5319
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDID 329
C H C NTPGS+ C C G HL DG+SC ++
Sbjct: 5320 EQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE 5358
Score = 64.1 bits (149), Expect = 1e-09
Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
++++EC C H C+N G + C C PGY+ TC D++EC + CG
Sbjct: 5431 VDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 176 CHNTEGSFTC---HCRPGYKADDFSKICVDIDECADNDALC 213
C N GS+ C C P Y+ D S C + C ND C
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFC--LKNCPPNDLEC 5527
Score = 60.9 bits (141), Expect = 1e-08
Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 15/197 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M++NEC P C H +C N G F C C PG H D C ++ + G
Sbjct: 5314 MDINECEQVPKPCAH-QCSNTPGSFKCICPPG------QHLLGDGKSCAGLERLPNYGTQ 5366
Query: 177 HNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+++ + R Y+ + + R T + R C G E
Sbjct: 5367 YSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTS-LSRTRRTIRKTCPEGSEA 5425
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C DIDEC T C + C+N G+YQC+C GY +
Sbjct: 5426 SHD--TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNV 5481
Query: 296 RC--QHSCVNTPGSYHC 310
C C N GSY C
Sbjct: 5482 HCGPNRMCFNMRGSYQC 5498
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 192 bits (468), Expect = 3e-48
Identities = 137/448 (30%), Positives = 200/448 (44%), Gaps = 51/448 (11%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHN 178
+ECAA C H C N +G + C C G + TC D++EC + C G DC N
Sbjct: 5109 DECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDN 5166
Query: 179 TEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
T GS+ C C G++ C DI+EC ++ C RC N GSF C C G +L
Sbjct: 5167 TIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCFNAIGSFHCGCEPGYQLK 5224
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXX 293
+ C D++EC +C + C+N G Y+C+ C G ++
Sbjct: 5225 GRK--CMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE-NGTCIDIDECKDG 5279
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C+++ C NT GSY C C G+ + GR C DI+EC +PC QC NT GS+
Sbjct: 5280 THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-AHQCSNTPGSFK 5338
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADL---ISTIIMMSVDELQKSVDP-----QIPELCG 403
C C G G +C ++ + S+ + ++ + P Q L
Sbjct: 5339 CICPPG--QHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYS 5396
Query: 404 AGSCHNTIGSFVCQ--------CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP 455
+ S + + + + CP+G + C D DECE T C +C N
Sbjct: 5397 SYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD---TCVDIDECE-NTDACQ--HECKNTF 5450
Query: 456 GSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGD 510
GS+QC C G++ +G TC+D+DECL N C P C N GS++C+ C Y+ D
Sbjct: 5451 GSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Query: 511 GYGLRTVCCVYSCVDID-ECANDPTLCE 537
+ C+ +C D ECA P E
Sbjct: 5511 PV---SGFCLKNCPPNDLECALSPYALE 5535
Score = 186 bits (454), Expect = 1e-46
Identities = 109/277 (39%), Positives = 139/277 (50%), Gaps = 43/277 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C HSC N G+Y+C+C +G + ADGR+C+DIDECA G C GQ C NT+GSY C
Sbjct: 5117 CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVR 5176
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G ++ G +CQDI+EC Q+S P C C N IGS
Sbjct: 5177 CGSGFRRTSDGL--SCQDINEC---------------QES-SP-----CHQ-RCFNAIGS 5212
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC--RCRDGW-RGDG 470
F C C GY +K G C D +EC C P C N G ++C C +G + +
Sbjct: 5213 FHCGCEPGYQLK---GRKCMDVNECRQNVC--RPDQHCKNTRGGYKCIDLCPNGMTKAEN 5267
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
TC D+DEC C C NT GS+RC+C GY+ G G C+DI+EC
Sbjct: 5268 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG-------RPCMDINECE 5320
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
P C + CSNTPG ++C C G DG+SC G
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAG 5356
Score = 161 bits (390), Expect = 8e-39
Identities = 129/420 (30%), Positives = 179/420 (42%), Gaps = 66/420 (15%)
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
++G + C G+ D C D DECA + C N G++ C C G+ +A D
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAAD 5141
Query: 239 RLSCKDIDECSITSGICSNGA-CENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXX 295
+C+DIDEC++ C G C+N +G+Y+CV C G+ + T
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSCQDINECQESS 5200
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG-ARPCGGGQCRNTVGSYTC-- 352
C C N GS+HC C G+ L+ GR C D++EC RP C+NT G Y C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRP--DQHCKNTRGGYKCID 5256
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G+ + G TC DIDEC D + + + QI C NT G
Sbjct: 5257 LCPNGMTKAENG---TCIDIDECKD--------GTHQCRYN---QI--------CENTRG 5294
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
S+ C CP GY G C D +ECE C A C N PGSF+C C G GDG
Sbjct: 5295 SYRCVCPRGYR-SQGVGRPCMDINECEQVPKPC--AHQCSNTPGSFKCICPPGQHLLGDG 5351
Query: 471 ATCEDVDECLTNNGGCHPRATCAN--------------TDGSFRCLCDTGYKGDGYGL-R 515
+C + E L N G + A S + Y+ L R
Sbjct: 5352 KSCAGL-ERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSR 5410
Query: 516 TVCCV-YSCVDIDECANDPTL----CEN-----GHCSNTPGGYECDCDVGFTRAADGRSC 565
T + +C + E ++D + CEN C NT G Y+C C G+ +G++C
Sbjct: 5411 TRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTC 5470
Score = 145 bits (351), Expect = 4e-34
Identities = 80/219 (36%), Positives = 110/219 (50%), Gaps = 14/219 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+++ECA C G+ C N +G + C C G+ + S +C D+NEC+ C
Sbjct: 5147 DIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR 5205
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCE--CGH 231
C N GSF C C PGY+ + C+D++EC N +CR + C NT G ++C C +
Sbjct: 5206 -CFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 232 GMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
GM A + +C DIDEC + C N CEN G+Y+CVC GY V
Sbjct: 5261 GMTKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC 5319
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDID 329
C H C NTPGS+ C C G HL DG+SC ++
Sbjct: 5320 EQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE 5358
Score = 64.1 bits (149), Expect = 1e-09
Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
++++EC C H C+N G + C C PGY+ TC D++EC + CG
Sbjct: 5431 VDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 176 CHNTEGSFTC---HCRPGYKADDFSKICVDIDECADNDALC 213
C N GS+ C C P Y+ D S C + C ND C
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFC--LKNCPPNDLEC 5527
Score = 60.9 bits (141), Expect = 1e-08
Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 15/197 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M++NEC P C H +C N G F C C PG H D C ++ + G
Sbjct: 5314 MDINECEQVPKPCAH-QCSNTPGSFKCICPPG------QHLLGDGKSCAGLERLPNYGTQ 5366
Query: 177 HNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+++ + R Y+ + + R T + R C G E
Sbjct: 5367 YSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTS-LSRTRRTIRKTCPEGSEA 5425
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C DIDEC T C + C+N G+YQC+C GY +
Sbjct: 5426 SHD--TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNV 5481
Query: 296 RC--QHSCVNTPGSYHC 310
C C N GSY C
Sbjct: 5482 HCGPNRMCFNMRGSYQC 5498
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 192 bits (468), Expect = 3e-48
Identities = 137/448 (30%), Positives = 200/448 (44%), Gaps = 51/448 (11%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHN 178
+ECAA C H C N +G + C C G + TC D++EC + C G DC N
Sbjct: 5109 DECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDN 5166
Query: 179 TEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
T GS+ C C G++ C DI+EC ++ C RC N GSF C C G +L
Sbjct: 5167 TIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCFNAIGSFHCGCEPGYQLK 5224
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXX 293
+ C D++EC +C + C+N G Y+C+ C G ++
Sbjct: 5225 GRK--CMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE-NGTCIDIDECKDG 5279
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C+++ C NT GSY C C G+ + GR C DI+EC +PC QC NT GS+
Sbjct: 5280 THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-AHQCSNTPGSFK 5338
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADL---ISTIIMMSVDELQKSVDP-----QIPELCG 403
C C G G +C ++ + S+ + ++ + P Q L
Sbjct: 5339 CICPPG--QHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYS 5396
Query: 404 AGSCHNTIGSFVCQ--------CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP 455
+ S + + + + CP+G + C D DECE T C +C N
Sbjct: 5397 SYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD---TCVDIDECE-NTDACQ--HECKNTF 5450
Query: 456 GSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGD 510
GS+QC C G++ +G TC+D+DECL N C P C N GS++C+ C Y+ D
Sbjct: 5451 GSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Query: 511 GYGLRTVCCVYSCVDID-ECANDPTLCE 537
+ C+ +C D ECA P E
Sbjct: 5511 PV---SGFCLKNCPPNDLECALSPYALE 5535
Score = 186 bits (454), Expect = 1e-46
Identities = 109/277 (39%), Positives = 139/277 (50%), Gaps = 43/277 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C HSC N G+Y+C+C +G + ADGR+C+DIDECA G C GQ C NT+GSY C
Sbjct: 5117 CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVR 5176
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G ++ G +CQDI+EC Q+S P C C N IGS
Sbjct: 5177 CGSGFRRTSDGL--SCQDINEC---------------QES-SP-----CHQ-RCFNAIGS 5212
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC--RCRDGW-RGDG 470
F C C GY +K G C D +EC C P C N G ++C C +G + +
Sbjct: 5213 FHCGCEPGYQLK---GRKCMDVNECRQNVC--RPDQHCKNTRGGYKCIDLCPNGMTKAEN 5267
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
TC D+DEC C C NT GS+RC+C GY+ G G C+DI+EC
Sbjct: 5268 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG-------RPCMDINECE 5320
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
P C + CSNTPG ++C C G DG+SC G
Sbjct: 5321 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAG 5356
Score = 161 bits (390), Expect = 8e-39
Identities = 129/420 (30%), Positives = 179/420 (42%), Gaps = 66/420 (15%)
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
++G + C G+ D C D DECA + C N G++ C C G+ +A D
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAAD 5141
Query: 239 RLSCKDIDECSITSGICSNGA-CENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXX 295
+C+DIDEC++ C G C+N +G+Y+CV C G+ + T
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSCQDINECQESS 5200
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG-ARPCGGGQCRNTVGSYTC-- 352
C C N GS+HC C G+ L+ GR C D++EC RP C+NT G Y C
Sbjct: 5201 PCHQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRP--DQHCKNTRGGYKCID 5256
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G+ + G TC DIDEC D + + + QI C NT G
Sbjct: 5257 LCPNGMTKAENG---TCIDIDECKD--------GTHQCRYN---QI--------CENTRG 5294
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
S+ C CP GY G C D +ECE C A C N PGSF+C C G GDG
Sbjct: 5295 SYRCVCPRGYR-SQGVGRPCMDINECEQVPKPC--AHQCSNTPGSFKCICPPGQHLLGDG 5351
Query: 471 ATCEDVDECLTNNGGCHPRATCAN--------------TDGSFRCLCDTGYKGDGYGL-R 515
+C + E L N G + A S + Y+ L R
Sbjct: 5352 KSCAGL-ERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSR 5410
Query: 516 TVCCV-YSCVDIDECANDPTL----CEN-----GHCSNTPGGYECDCDVGFTRAADGRSC 565
T + +C + E ++D + CEN C NT G Y+C C G+ +G++C
Sbjct: 5411 TRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTC 5470
Score = 145 bits (351), Expect = 4e-34
Identities = 80/219 (36%), Positives = 110/219 (50%), Gaps = 14/219 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+++ECA C G+ C N +G + C C G+ + S +C D+NEC+ C
Sbjct: 5147 DIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR 5205
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCE--CGH 231
C N GSF C C PGY+ + C+D++EC N +CR + C NT G ++C C +
Sbjct: 5206 -CFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 232 GMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
GM A + +C DIDEC + C N CEN G+Y+CVC GY V
Sbjct: 5261 GMTKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC 5319
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDID 329
C H C NTPGS+ C C G HL DG+SC ++
Sbjct: 5320 EQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE 5358
Score = 64.1 bits (149), Expect = 1e-09
Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
++++EC C H C+N G + C C PGY+ TC D++EC + CG
Sbjct: 5431 VDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 176 CHNTEGSFTC---HCRPGYKADDFSKICVDIDECADNDALC 213
C N GS+ C C P Y+ D S C + C ND C
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFC--LKNCPPNDLEC 5527
Score = 60.9 bits (141), Expect = 1e-08
Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 15/197 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M++NEC P C H +C N G F C C PG H D C ++ + G
Sbjct: 5314 MDINECEQVPKPCAH-QCSNTPGSFKCICPPG------QHLLGDGKSCAGLERLPNYGTQ 5366
Query: 177 HNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+++ + R Y+ + + R T + R C G E
Sbjct: 5367 YSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTS-LSRTRRTIRKTCPEGSEA 5425
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C DIDEC T C + C+N G+YQC+C GY +
Sbjct: 5426 SHD--TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNV 5481
Query: 296 RC--QHSCVNTPGSYHC 310
C C N GSY C
Sbjct: 5482 HCGPNRMCFNMRGSYQC 5498
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 192 bits (468), Expect = 3e-48
Identities = 137/448 (30%), Positives = 200/448 (44%), Gaps = 51/448 (11%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHN 178
+ECAA C H C N +G + C C G + TC D++EC + C G DC N
Sbjct: 2147 DECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDN 2204
Query: 179 TEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
T GS+ C C G++ C DI+EC ++ C RC N GSF C C G +L
Sbjct: 2205 TIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCFNAIGSFHCGCEPGYQLK 2262
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXX 293
+ C D++EC +C + C+N G Y+C+ C G ++
Sbjct: 2263 GRK--CMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE-NGTCIDIDECKDG 2317
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C+++ C NT GSY C C G+ + GR C DI+EC +PC QC NT GS+
Sbjct: 2318 THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-AHQCSNTPGSFK 2376
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADL---ISTIIMMSVDELQKSVDP-----QIPELCG 403
C C G G +C ++ + S+ + ++ + P Q L
Sbjct: 2377 CICPPG--QHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYS 2434
Query: 404 AGSCHNTIGSFVCQ--------CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP 455
+ S + + + + CP+G + C D DECE T C +C N
Sbjct: 2435 SYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD---TCVDIDECE-NTDACQ--HECKNTF 2488
Query: 456 GSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGD 510
GS+QC C G++ +G TC+D+DECL N C P C N GS++C+ C Y+ D
Sbjct: 2489 GSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 2548
Query: 511 GYGLRTVCCVYSCVDID-ECANDPTLCE 537
+ C+ +C D ECA P E
Sbjct: 2549 PV---SGFCLKNCPPNDLECALSPYALE 2573
Score = 186 bits (454), Expect = 1e-46
Identities = 109/277 (39%), Positives = 139/277 (50%), Gaps = 43/277 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C HSC N G+Y+C+C +G + ADGR+C+DIDECA G C GQ C NT+GSY C
Sbjct: 2155 CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVR 2214
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G ++ G +CQDI+EC Q+S P C C N IGS
Sbjct: 2215 CGSGFRRTSDGL--SCQDINEC---------------QES-SP-----CHQ-RCFNAIGS 2250
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC--RCRDGW-RGDG 470
F C C GY +K G C D +EC C P C N G ++C C +G + +
Sbjct: 2251 FHCGCEPGYQLK---GRKCMDVNECRQNVC--RPDQHCKNTRGGYKCIDLCPNGMTKAEN 2305
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
TC D+DEC C C NT GS+RC+C GY+ G G C+DI+EC
Sbjct: 2306 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG-------RPCMDINECE 2358
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
P C + CSNTPG ++C C G DG+SC G
Sbjct: 2359 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAG 2394
Score = 161 bits (390), Expect = 8e-39
Identities = 129/420 (30%), Positives = 179/420 (42%), Gaps = 66/420 (15%)
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
++G + C G+ D C D DECA + C N G++ C C G+ +A D
Sbjct: 2122 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAAD 2179
Query: 239 RLSCKDIDECSITSGICSNGA-CENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXX 295
+C+DIDEC++ C G C+N +G+Y+CV C G+ + T
Sbjct: 2180 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSCQDINECQESS 2238
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG-ARPCGGGQCRNTVGSYTC-- 352
C C N GS+HC C G+ L+ GR C D++EC RP C+NT G Y C
Sbjct: 2239 PCHQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRP--DQHCKNTRGGYKCID 2294
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G+ + G TC DIDEC D + + + QI C NT G
Sbjct: 2295 LCPNGMTKAENG---TCIDIDECKD--------GTHQCRYN---QI--------CENTRG 2332
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
S+ C CP GY G C D +ECE C A C N PGSF+C C G GDG
Sbjct: 2333 SYRCVCPRGYR-SQGVGRPCMDINECEQVPKPC--AHQCSNTPGSFKCICPPGQHLLGDG 2389
Query: 471 ATCEDVDECLTNNGGCHPRATCAN--------------TDGSFRCLCDTGYKGDGYGL-R 515
+C + E L N G + A S + Y+ L R
Sbjct: 2390 KSCAGL-ERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSR 2448
Query: 516 TVCCV-YSCVDIDECANDPTL----CEN-----GHCSNTPGGYECDCDVGFTRAADGRSC 565
T + +C + E ++D + CEN C NT G Y+C C G+ +G++C
Sbjct: 2449 TRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTC 2508
Score = 145 bits (351), Expect = 4e-34
Identities = 80/219 (36%), Positives = 110/219 (50%), Gaps = 14/219 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+++ECA C G+ C N +G + C C G+ + S +C D+NEC+ C
Sbjct: 2185 DIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR 2243
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCE--CGH 231
C N GSF C C PGY+ + C+D++EC N +CR + C NT G ++C C +
Sbjct: 2244 -CFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPN 2298
Query: 232 GMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
GM A + +C DIDEC + C N CEN G+Y+CVC GY V
Sbjct: 2299 GMTKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC 2357
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDID 329
C H C NTPGS+ C C G HL DG+SC ++
Sbjct: 2358 EQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE 2396
Score = 64.1 bits (149), Expect = 1e-09
Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
++++EC C H C+N G + C C PGY+ TC D++EC + CG
Sbjct: 2469 VDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 2526
Query: 176 CHNTEGSFTC---HCRPGYKADDFSKICVDIDECADNDALC 213
C N GS+ C C P Y+ D S C + C ND C
Sbjct: 2527 CFNMRGSYQCIDTPCPPNYQRDPVSGFC--LKNCPPNDLEC 2565
Score = 60.9 bits (141), Expect = 1e-08
Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 15/197 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M++NEC P C H +C N G F C C PG H D C ++ + G
Sbjct: 2352 MDINECEQVPKPCAH-QCSNTPGSFKCICPPG------QHLLGDGKSCAGLERLPNYGTQ 2404
Query: 177 HNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+++ + R Y+ + + R T + R C G E
Sbjct: 2405 YSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTS-LSRTRRTIRKTCPEGSEA 2463
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C DIDEC T C + C+N G+YQC+C GY +
Sbjct: 2464 SHD--TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNV 2519
Query: 296 RC--QHSCVNTPGSYHC 310
C C N GSY C
Sbjct: 2520 HCGPNRMCFNMRGSYQC 2536
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 192 bits (467), Expect = 4e-48
Identities = 137/448 (30%), Positives = 199/448 (44%), Gaps = 51/448 (11%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHN 178
+ECAA C H C N +G + C C G + TC D++EC + C G DC N
Sbjct: 5110 DECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDN 5167
Query: 179 TEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
T GS+ C C G++ C DI+EC ++ C RC N GSF C C G +L
Sbjct: 5168 TIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQ-RCFNAIGSFHCGCEPGYQLK 5225
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXX 293
+ C D++EC +C + C+N G Y+C+ C G ++
Sbjct: 5226 GRK--CMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE-NGTCIDIDECKDG 5280
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C+++ C NT SY C C G+ + GR C DIDEC +PC QC NT GS+
Sbjct: 5281 THQCRYNQICENTRSSYRCVCPRGYRSQGVGRPCMDIDECEQVPKPC-AHQCSNTPGSFK 5339
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADL---ISTIIMMSVDELQKSVDP-----QIPELCG 403
C C G G +C ++ + S+ + ++ + P Q L
Sbjct: 5340 CICPPG--QHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYS 5397
Query: 404 AGSCHNTIGSFVCQ--------CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP 455
+ S + + + + CP+G + C D DECE T C +C N
Sbjct: 5398 SYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD---TCVDIDECE-NTDACQ--HECKNTF 5451
Query: 456 GSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGD 510
GS+QC C G++ +G TC+D+DECL N C P C N GS++C+ C Y+ D
Sbjct: 5452 GSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5511
Query: 511 GYGLRTVCCVYSCVDID-ECANDPTLCE 537
+ C+ +C D ECA P E
Sbjct: 5512 PV---SGFCLKNCPPNDLECALSPYALE 5536
Score = 186 bits (453), Expect = 2e-46
Identities = 109/277 (39%), Positives = 138/277 (49%), Gaps = 43/277 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C HSC N G+Y+C+C +G + ADGR+C+DIDECA G C GQ C NT+GSY C
Sbjct: 5118 CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVR 5177
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G ++ G +CQDI+EC Q+S P C C N IGS
Sbjct: 5178 CGSGFRRTSDGL--SCQDINEC---------------QES-SP-----CHQ-RCFNAIGS 5213
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC--RCRDGW-RGDG 470
F C C GY +K G C D +EC C P C N G ++C C +G + +
Sbjct: 5214 FHCGCEPGYQLK---GRKCMDVNECRQNVC--RPDQHCKNTRGGYKCIDLCPNGMTKAEN 5268
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
TC D+DEC C C NT S+RC+C GY+ G G C+DIDEC
Sbjct: 5269 GTCIDIDECKDGTHQCRYNQICENTRSSYRCVCPRGYRSQGVG-------RPCMDIDECE 5321
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
P C + CSNTPG ++C C G DG+SC G
Sbjct: 5322 QVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAG 5357
Score = 160 bits (389), Expect = 1e-38
Identities = 129/420 (30%), Positives = 178/420 (42%), Gaps = 66/420 (15%)
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
++G + C G+ D C D DECA + C N G++ C C G+ +A D
Sbjct: 5085 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAAD 5142
Query: 239 RLSCKDIDECSITSGICSNGA-CENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXX 295
+C+DIDEC++ C G C+N +G+Y+CV C G+ + T
Sbjct: 5143 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSCQDINECQESS 5201
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG-ARPCGGGQCRNTVGSYTC-- 352
C C N GS+HC C G+ L+ GR C D++EC RP C+NT G Y C
Sbjct: 5202 PCHQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRP--DQHCKNTRGGYKCID 5257
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G+ + G TC DIDEC D + + + QI C NT
Sbjct: 5258 LCPNGMTKAENG---TCIDIDECKD--------GTHQCRYN---QI--------CENTRS 5295
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
S+ C CP GY G C D DECE C A C N PGSF+C C G GDG
Sbjct: 5296 SYRCVCPRGYR-SQGVGRPCMDIDECEQVPKPC--AHQCSNTPGSFKCICPPGQHLLGDG 5352
Query: 471 ATCEDVDECLTNNGGCHPRATCAN--------------TDGSFRCLCDTGYKGDGYGL-R 515
+C + E L N G + A S + Y+ L R
Sbjct: 5353 KSCAGL-ERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSR 5411
Query: 516 TVCCV-YSCVDIDECANDPTL----CEN-----GHCSNTPGGYECDCDVGFTRAADGRSC 565
T + +C + E ++D + CEN C NT G Y+C C G+ +G++C
Sbjct: 5412 TRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTC 5471
Score = 142 bits (345), Expect = 2e-33
Identities = 79/219 (36%), Positives = 109/219 (49%), Gaps = 14/219 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+++ECA C G+ C N +G + C C G+ + S +C D+NEC+ C
Sbjct: 5148 DIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR 5206
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCE--CGH 231
C N GSF C C PGY+ + C+D++EC N +CR + C NT G ++C C +
Sbjct: 5207 -CFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPN 5261
Query: 232 GMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
GM A + +C DIDEC + C N CEN +Y+CVC GY V
Sbjct: 5262 GMTKAENG-TCIDIDECKDGTHQCRYNQICENTRSSYRCVCPRGYRSQGVGRPCMDIDEC 5320
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDID 329
C H C NTPGS+ C C G HL DG+SC ++
Sbjct: 5321 EQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE 5359
Score = 64.1 bits (149), Expect = 1e-09
Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
++++EC C H C+N G + C C PGY+ TC D++EC + CG
Sbjct: 5432 VDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5489
Query: 176 CHNTEGSFTC---HCRPGYKADDFSKICVDIDECADNDALC 213
C N GS+ C C P Y+ D S C + C ND C
Sbjct: 5490 CFNMRGSYQCIDTPCPPNYQRDPVSGFC--LKNCPPNDLEC 5528
Score = 58.8 bits (136), Expect = 5e-08
Identities = 51/197 (25%), Positives = 73/197 (37%), Gaps = 15/197 (7%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
M+++EC P C H +C N G F C C PG H D C ++ + G
Sbjct: 5315 MDIDECEQVPKPCAH-QCSNTPGSFKCICPPG------QHLLGDGKSCAGLERLPNYGTQ 5367
Query: 177 HNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+++ + R Y+ + + R T + R C G E
Sbjct: 5368 YSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTS-LSRTRRTIRKTCPEGSEA 5426
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ D +C DIDEC T C + C+N G+YQC+C GY +
Sbjct: 5427 SHD--TCVDIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNV 5482
Query: 296 RC--QHSCVNTPGSYHC 310
C C N GSY C
Sbjct: 5483 HCGPNRMCFNMRGSYQC 5499
>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 191 bits (465), Expect = 7e-48
Identities = 149/463 (32%), Positives = 200/463 (43%), Gaps = 70/463 (15%)
Query: 120 NECAAFPGLCGHGRCRNL-LGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCH 177
N C P G G C L L + C C PG+ S C + C C +G C
Sbjct: 104 NACLTNPCRNG-GTCDLLTLTEYKCRCPPGWSGKS----CQQADPC--ASNPCANGGQCL 156
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELA 236
E S+ CHC P + + D++EC LCR GG C N GS+RC C
Sbjct: 157 PFEASYICHCPPSFHGPTCRQ---DVNECGQKPGLCRHGGTCHNEVGSYRCVC-RATHTG 212
Query: 237 PDRLSC-KDIDECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
P+ C + CS + C NG G T++C C G+ + +
Sbjct: 213 PN---CERPYVPCSPSP--CQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGN--- 264
Query: 294 XXRCQH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGS 349
C++ +CV+ +Y+C C W G+ C D+DEC C GG C NT G
Sbjct: 265 --NCKNGGACVDGVNTYNCRCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGG 318
Query: 350 YTCTCTDGLVPSAAG------AKPTCQDIDECADLISTIIMMS----VDELQKSVDPQIP 399
Y C C +G A C C D +++ L D I
Sbjct: 319 YNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS 378
Query: 400 ELCGAGS-CH-NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLP 455
C GS C N + G +C CP GY+ GPAC+ D DEC LG C A CIN
Sbjct: 379 NPCNEGSNCDTNPVNGKAICTCPSGYT-----GPACSQDVDECSLGANPCEHAGKCINTL 433
Query: 456 GSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
GSF+C+C G+ G CE DV+EC++N C ATC + G F+C+C GY+G
Sbjct: 434 GSFECQCLQGY--TGPRCEIDVNECVSN--PCQNDATCLDQIGEFQCICMPGYEG----- 484
Query: 515 RTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
V+ V+ DECA+ P L NG C + ++C+C GFT
Sbjct: 485 -----VHCEVNTDECASSPCL-HNGRCLDKINEFQCECPTGFT 521
Score = 182 bits (443), Expect = 3e-45
Identities = 142/466 (30%), Positives = 205/466 (43%), Gaps = 77/466 (16%)
Query: 118 EVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGD 175
+V+EC+ C H G+C N LG F C C GY +DVNEC V C D
Sbjct: 412 DVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCE---IDVNEC--VSNPCQNDAT 466
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C + G F C C PGY+ V+ DECA + L GRC++ F+CEC G
Sbjct: 467 CLDQIGEFQCICMPGYEGVHCE---VNTDECASSPCL-HNGRCLDKINEFQCECPTGFT- 521
Query: 236 APDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
L D+DEC+ T C NGA C + TY CVC EGY + +
Sbjct: 522 --GHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGYTGTHCE-----VDIDECDP 572
Query: 295 XRCQH-SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYT 351
C + SC + ++ C CR G+ G C +I+EC+ ++PC GG C++ +Y
Sbjct: 573 DPCHYGSCKDGVATFTCLCRPGY----TGHHCETNINECS--SQPCRHGGTCQDRDNAYL 626
Query: 352 CTCTDGLVPSAAGAKPTCQ-DIDECAD--LISTIIMMSVDELQKSVDP---------QIP 399
C C G P C+ ++D+CA S + +D + + +P I
Sbjct: 627 CFCLKGTTG------PNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINID 680
Query: 400 ELCG-----AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCIN 453
E G G+C + I F C+CP+GY P C + +EC C D +N
Sbjct: 681 ECAGNPCHNGGTCEDGINGFTCRCPEGY-----HDPTCLSEVNECNSNPCVHGACRDSLN 735
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
++C C GW G + +EC +N C TC + + C C G+ G
Sbjct: 736 ---GYKCDCDPGWSGTNCDINN-NECESNP--CVNGGTCKDMTSGYVCTCREGFSGPN-- 787
Query: 514 LRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRA 559
C +I+ECA++P L G C + GY+C+C + +T A
Sbjct: 788 -----CQ---TNINECASNPCL-NQGTCIDDVAGYKCNCLLPYTGA 824
Score = 172 bits (418), Expect = 3e-42
Identities = 137/453 (30%), Positives = 191/453 (42%), Gaps = 80/453 (17%)
Query: 116 QMEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC PGLC H G C N +G + C C + + V + +G G
Sbjct: 176 RQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNG----G 231
Query: 175 DCHNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C T + + C C PG+ + + +ID+C N+ GG CV+ ++ C C
Sbjct: 232 TCRPTGDVTHECACLPGFTGQNCEE---NIDDCPGNNCK-NGGACVDGVNTYNCRCPPEW 287
Query: 234 ELAPDRLSCKDIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+ +D+DEC + C N G C N G Y CVC G+ +
Sbjct: 288 ---TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAA- 343
Query: 293 XXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQC-RNTV- 347
C H +C + S++C C G G C D C + PC G C N V
Sbjct: 344 ----CFHGATCHDRVASFYCECPHG----RTGLLCHLNDACI--SNPCNEGSNCDTNPVN 393
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
G CTC G A QD+DEC+ + + + AG C
Sbjct: 394 GKAICTCPSGYTGPACS-----QDVDECS--------LGANPCEH-----------AGKC 429
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
NT+GSF CQC GY+ GP C D +EC + C A C++ G FQC C G+
Sbjct: 430 INTLGSFECQCLQGYT-----GPRCEIDVNECV--SNPCQNDATCLDQIGEFQCICMPGY 482
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+G CE + DEC ++ C C + F+C C TG+ G C Y D
Sbjct: 483 --EGVHCEVNTDECASS--PCLHNGRCLDKINEFQCECPTGFTGH-------LCQY---D 528
Query: 526 IDECANDPTLCENG-HCSNTPGGYECDCDVGFT 557
+DECA+ P C+NG C + P Y C C G+T
Sbjct: 529 VDECASTP--CKNGAKCLDGPNTYTCVCTEGYT 559
Score = 159 bits (386), Expect = 2e-38
Identities = 128/448 (28%), Positives = 194/448 (43%), Gaps = 68/448 (15%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPG 190
G C + + + C C P + + + DV+EC+++ C +G CHNT G + C C G
Sbjct: 270 GACVDGVNTYNCRCPPEW---TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNG 326
Query: 191 YKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSI 250
+ +D S+ +ID+CA + A G C + SF CEC HG L C D C
Sbjct: 327 WTGEDCSE---NIDDCA-SAACFHGATCHDRVASFYCECPHGRT----GLLCHLNDAC-- 376
Query: 251 TSGICSNGA-CENQM--GTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTP 305
S C+ G+ C+ G C C GY T + C+H+ C+NT
Sbjct: 377 ISNPCNEGSNCDTNPVNGKAICTCPSGY---TGPACSQDVDECSLGANPCEHAGKCINTL 433
Query: 306 GSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGL----- 358
GS+ C C +G+ G C D++EC + PC C + +G + C C G
Sbjct: 434 GSFECQCLQGY----TGPRCEIDVNECV--SNPCQNDATCLDQIGEFQCICMPGYEGVHC 487
Query: 359 -VPSAAGAKPTCQDIDECADLISTIIM-----MSVDELQKSVDPQIPELCGAGS-CHNTI 411
V + A C C D I+ + Q VD C G+ C +
Sbjct: 488 EVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGP 547
Query: 412 GSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
++ C C +GY+ G C D DEC+ C D + +F C CR G+ G
Sbjct: 548 NTYTCVCTEGYT-----GTHCEVDIDECDPDPCHYGSCKDGV---ATFTCLCRPGYTGHH 599
Query: 471 ATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
CE +++EC ++ C TC + D ++ C C G G C +++D+C
Sbjct: 600 --CETNINEC--SSQPCRHGGTCQDRDNAYLCFCLKGTTGPN-------CE---INLDDC 645
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFT 557
A+ P C++G C + GYEC C+ G+T
Sbjct: 646 ASSP--CDSGTCLDKIDGYECACEPGYT 671
Score = 158 bits (384), Expect = 4e-38
Identities = 140/451 (31%), Positives = 192/451 (42%), Gaps = 87/451 (19%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
EVNEC + P C HG CR+ L G+ CDC PG+ S + ++ NECE V G G C
Sbjct: 716 EVNECNSNP--CVHGACRDSLNGYKCDCDPGW---SGTNCDINNNECESNPCVNG-GTCK 769
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
+ + C CR G+ + +I+ECA N L G C++ ++C C L P
Sbjct: 770 DMTSGYVCTCREGFSGPNCQ---TNINECASNPCL-NQGTCIDDVAGYKCNC-----LLP 820
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQ---CVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ ++ C NG Q Y+ CVC G+ T +
Sbjct: 821 YTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCE-----VDINECVL 875
Query: 295 XRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C+H SC NT G Y C C+ G+ GR+C DID+C PC GG C + + +
Sbjct: 876 SPCRHGASCQNTHGGYRCHCQAGY----SGRNCETDIDDCR--PNPCHNGGSCTDGINTA 929
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHN 409
C C G + +DI+ECA DP C G +C +
Sbjct: 930 FCDCLPGFRGTFCE-----EDINECAS-----------------DP-----CRNGANCTD 962
Query: 410 TIGSFVCQCPDGYS-VKPEQG-PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR 467
+ S+ C CP G+S + E P CT+ GTC D IN SF C C G+
Sbjct: 963 CVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTC-----VDGIN---SFTCLCPPGF- 1013
Query: 468 GDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI 526
G+ C+ DV+EC ++ C TC + GS+RC C GY G V+ C D
Sbjct: 1014 -TGSYCQHDVNEC--DSQPCLHGGTCQDGCGSYRCTCPQGYTGP----NCQNLVHWC-DS 1065
Query: 527 DECANDPTLCENGHCSNTPGGYECDCDVGFT 557
C N G C T Y C+C G+T
Sbjct: 1066 SPCKN------GGKCWQTHTQYRCECPSGWT 1090
Score = 153 bits (372), Expect = 1e-36
Identities = 130/465 (27%), Positives = 192/465 (41%), Gaps = 68/465 (14%)
Query: 122 CAAFPGLCGHGRCRNL--LGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG-DCH 177
CA P G G CR F+C C G++ TC VD+NEC + C G C
Sbjct: 833 CAPSPCRNG-GECRQSEDYESFSCVCPTGWQ----GQTCEVDINECVL--SPCRHGASCQ 885
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT G + CHC+ GY + DID+C N GG C + + C+C G
Sbjct: 886 NTHGGYRCHCQAGYSGRNCE---TDIDDCRPNPCH-NGGSCTDGINTAFCDCLPGFR--- 938
Query: 238 DRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+DI+EC+ S C NGA C + + +Y C C G++ +++
Sbjct: 939 GTFCEEDINECA--SDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG 996
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTC 354
+CV+ S+ C C G+ G C+ D++EC ++PC GG C++ GSY CTC
Sbjct: 997 ---TCVDGINSFTCLCPPGF----TGSYCQHDVNEC--DSQPCLHGGTCQDGCGSYRCTC 1047
Query: 355 TDGLV--------------PSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKS 393
G P G K C+ L + +S + +
Sbjct: 1048 PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQR 1107
Query: 394 VDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADC 451
+ LC G C + + C+C GY+ G C D DEC C A C
Sbjct: 1108 QGVDVARLCQHGGLCVDAGNTHHCRCQAGYT-----GSYCEDLVDECS--PSPCQNGATC 1160
Query: 452 INLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG 511
+ G + C+C G+ G + E++DECL++ C TC + +++C C G +G
Sbjct: 1161 TDYLGGYSCKCVAGYHGVNCS-EEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQGVH 1217
Query: 512 YGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
+ C +D + P NG C + GGY C C GF
Sbjct: 1218 CEINVDDCN---PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGF 1259
Score = 149 bits (362), Expect = 2e-35
Identities = 120/428 (28%), Positives = 176/428 (41%), Gaps = 66/428 (15%)
Query: 118 EVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++NECA+ P C +G C + + +TC C G+ + D E +G G C
Sbjct: 945 DINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG----GTC 998
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
+ SFTC C PG+ S D++EC D+ GG C + GS+RC C G
Sbjct: 999 VDGINSFTCLCPPGFTG---SYCQHDVNEC-DSQPCLHGGTCQDGCGSYRCTCPQGYT-G 1053
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ-----STVKSHXXXXXXXX 291
P+ C+++ +S + G C Y+C C G+ +V
Sbjct: 1054 PN---CQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGV 1110
Query: 292 XXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPC-GGGQCRNTV 347
CQH CV+ ++HC C+ G+ G C D +DEC+ PC G C + +
Sbjct: 1111 DVARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDLVDECSPS--PCQNGATCTDYL 1164
Query: 348 GSYTCTCTDGLVPSAAGAK------PTCQDIDECADLISTI------------IMMSVDE 389
G Y+C C G + CQ+ C DL +T ++VD+
Sbjct: 1165 GGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDD 1224
Query: 390 LQKSVDP--QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCH 446
VDP + P+ G+C + +G + C CP G+ G C D +EC CD
Sbjct: 1225 CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV-----GERCEGDVNECLSNPCDAR 1279
Query: 447 PAADCINLPGSFQCRCRDGWRGDGATCEDV-DEC----LTNNGGCHPRATCANTDGSFRC 501
+C+ F C CR G G CE V + C N G C A +NT F C
Sbjct: 1280 GTQNCVQRVNDFHCECRAG--HTGRRCESVINGCKGKPCKNGGTC---AVASNTARGFIC 1334
Query: 502 LCDTGYKG 509
C G++G
Sbjct: 1335 KCPAGFEG 1342
Score = 147 bits (356), Expect = 1e-34
Identities = 132/481 (27%), Positives = 200/481 (41%), Gaps = 112/481 (23%)
Query: 119 VNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG--- 174
+++CA+ C HG C + + F C+C G + +N+ + C +G
Sbjct: 336 IDDCAS--AACFHGATCHDRVASFYCECPHG-----RTGLLCHLNDA-CISNPCNEGSNC 387
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGM 233
D + G C C GY S+ D+DEC+ C G+C+NT GSF C+C G
Sbjct: 388 DTNPVNGKAICTCPSGYTGPACSQ---DVDECSLGANPCEHAGKCINTLGSFECQCLQGY 444
Query: 234 ELAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
P C+ D++EC S C N A C +Q+G +QC+C GY + +
Sbjct: 445 T-GP---RCEIDVNEC--VSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSP 498
Query: 292 XXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTV 347
C H+ C++ + C C G+ G C+ D+DECA + PC G +C +
Sbjct: 499 -----CLHNGRCLDKINEFQCECPTGF----TGHLCQYDVDECA--STPCKNGAKCLDGP 547
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
+YTC CT+G + DIDEC P+ C GSC
Sbjct: 548 NTYTCVCTEGYTGTHCEV-----DIDECD----------------------PDPCHYGSC 580
Query: 408 HNTIGSFVCQCPDGY------------SVKP-EQGPACTDDD--------------ECEL 440
+ + +F C C GY S +P G C D D CE+
Sbjct: 581 KDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI 640
Query: 441 GTCDCH----PAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTD 496
DC + C++ ++C C G+ G ++DEC N CH TC +
Sbjct: 641 NLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNI-NIDECAGN--PCHNGGTCEDGI 697
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
F C C GY C+ +++EC ++P C +G C ++ GY+CDCD G+
Sbjct: 698 NGFTCRCPEGY-------HDPTCL---SEVNECNSNP--CVHGACRDSLNGYKCDCDPGW 745
Query: 557 T 557
+
Sbjct: 746 S 746
Score = 138 bits (334), Expect = 5e-32
Identities = 127/485 (26%), Positives = 199/485 (41%), Gaps = 82/485 (16%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
++++NEC P C HG C+N GG+ C C GY S + D+++C C +G
Sbjct: 867 EVDINECVLSP--CRHGASCQNTHGGYRCHCQAGY---SGRNCETDIDDCR--PNPCHNG 919
Query: 175 -DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PG++ + DI+ECA +D G C + S+ C C G
Sbjct: 920 GSCTDGINTAFCDCLPGFRGTFCEE---DINECA-SDPCRNGANCTDCVDSYTCTCPAGF 975
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX-X 292
+ D E S +G G C + + ++ C+C G+ S +
Sbjct: 976 SGIHCENNTPDCTESSCFNG----GTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCL 1031
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQCRNTVGSYT 351
CQ C GSY CTC +G+ G +C+++ + PC GG+C T Y
Sbjct: 1032 HGGTCQDGC----GSYRCTCPQGY----TGPNCQNLVHWCDSS-PCKNGGKCWQTHTQYR 1082
Query: 352 CTCTDGL------VPSAA----------GAKPTCQDIDECADLISTIIMM-----SVDEL 390
C C G VPS + CQ C D +T +
Sbjct: 1083 CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYC 1142
Query: 391 QKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
+ VD P C G+ C + +G + C+C GY G C+++ DEC + C
Sbjct: 1143 EDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY-----HGVNCSEEIDECL--SHPCQNG 1195
Query: 449 ADCINLPGSFQCRCRDGWRGDGATCE-DVDEC------LTNNGGCHPRATCANTDGSFRC 501
C++LP +++C C G +G CE +VD+C ++ + C TC + G + C
Sbjct: 1196 GTCLDLPNTYKCSCPRGTQG--VHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC 1253
Query: 502 LCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGFTRAA 560
C G+ G+ C D++EC ++P +C + C+C G T
Sbjct: 1254 TCPPGFVGER-------CE---GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT--- 1300
Query: 561 DGRSC 565
GR C
Sbjct: 1301 -GRRC 1304
Score = 118 bits (283), Expect = 7e-26
Identities = 114/430 (26%), Positives = 170/430 (39%), Gaps = 62/430 (14%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYE-KDSKN--HTCVDVNECEIVDGVCG 172
Q +VNEC + P L G G C++ G + C C GY + +N H C D + C+
Sbjct: 1019 QHDVNECDSQPCLHG-GTCQDGCGSYRCTCPQGYTGPNCQNLVHWC-DSSPCK------N 1070
Query: 173 DGDCHNTEGSFTCHCRPGYKA--DDFSKICVDID---ECADNDALCR-GGRCVNTAGSFR 226
G C T + C C G+ D + ++ + D LC+ GG CV+ +
Sbjct: 1071 GGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH 1130
Query: 227 CECGHGMELAPDRLSCKD-IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHX 284
C C G + C+D +DECS + C NGA C + +G Y C C GY
Sbjct: 1131 CRCQAGYTGS----YCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 1184
Query: 285 XXXXXXXXXXXRCQH--SCVNTPGSYHCTC---REGWHLRADGRSCRD-IDECAGGARPC 338
CQ+ +C++ P +Y C+C +G H + C +D + +
Sbjct: 1185 DECLSHP-----CQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCF 1239
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAA-GAKPTC-------QDIDECADLISTI-IMMSVDE 389
G C + VG Y+CTC G V G C + C ++
Sbjct: 1240 NNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH 1299
Query: 390 LQKSVDPQIPELCG-----AGSC---HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
+ + I G G+C NT F+C+CP G+ +G C ++D G
Sbjct: 1300 TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF-----EGATC-ENDARTCG 1353
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGS--F 499
+ C CI+ P S C C + G CL N C+ + TC T S +
Sbjct: 1354 SLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGN-PCYNQGTCEPTSESPFY 1412
Query: 500 RCLCDTGYKG 509
RCLC + G
Sbjct: 1413 RCLCPAKFNG 1422
Score = 115 bits (276), Expect = 5e-25
Identities = 108/364 (29%), Positives = 145/364 (39%), Gaps = 71/364 (19%)
Query: 206 CADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSN-GAC--- 260
C+ C GG+C G+ C CG G + P C+D + C T C N G C
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCG-GAFVGP---RCQDPNPCLSTP--CKNAGTCHVV 77
Query: 261 -ENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC-VNTPGSYHCTCREGWHL 318
+ Y C C G++ + R +C + T Y C C GW
Sbjct: 78 DRRGVADYACSCALGFSGPLCLT--PLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGW-- 133
Query: 319 RADGRSCRDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTC-QDIDECA 376
G+SC+ D CA + PC GGQC SY C C PS G PTC QD++EC
Sbjct: 134 --SGKSCQQADPCA--SNPCANGGQCLPFEASYICHCP----PSFHG--PTCRQDVNECG 183
Query: 377 DLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGP-ACTD 434
Q P LC G+CHN +GS+ C C ++ + P
Sbjct: 184 --------------------QKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCS 223
Query: 435 DDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCAN 494
C+ G C P D + +C C G+ G E++D+C NN C C +
Sbjct: 224 PSPCQNGG-TCRPTGDV-----THECACLPGFTGQNCE-ENIDDCPGNN--CKNGGACVD 274
Query: 495 TDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCD 553
++ C C + G Y D+DEC P C+N G C NT GGY C C
Sbjct: 275 GVNTYNCRCPPEWTGQ----------YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCV 324
Query: 554 VGFT 557
G+T
Sbjct: 325 NGWT 328
>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 191 bits (465), Expect = 7e-48
Identities = 111/331 (33%), Positives = 153/331 (46%), Gaps = 30/331 (9%)
Query: 181 GSFTCHC-RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDR 239
G + CH + GY + D+DEC ++ C+ RCVNT GS+ CEC G L D
Sbjct: 35 GCYPCHLGQAGYPVSAGDQR-PDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDS 92
Query: 240 LSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
+C I+ C++ +G C + + + ++C C G+ H C H
Sbjct: 93 RTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH 152
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C G C C G+ L ADG++C D+DECA G C G C NT GS+ C C G
Sbjct: 153 RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYE 211
Query: 360 PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCP 419
A G + C I+ M V+ + + C G H + G +C CP
Sbjct: 212 LGADGRQ--CYRIE----------MEIVNSCEANNGG-----CSHGCSHTSAGP-LCTCP 253
Query: 420 DGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVD 477
GY + +Q C D D+C C C C N PG ++C C G+R DG CEDVD
Sbjct: 254 RGYELDTDQR-TCIDVDDCADSPC-CQQV--CTNNPGGYECGCYAGYRLSADGCGCEDVD 309
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
EC ++ GGC C N GSF+C C+ GY+
Sbjct: 310 ECASSRGGCEHH--CTNLAGSFQCSCEAGYR 338
Score = 178 bits (433), Expect = 5e-44
Identities = 91/264 (34%), Positives = 127/264 (48%), Gaps = 12/264 (4%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC G C H RC N G + C+C PG+ + + TC+ +N C + +G C
Sbjct: 56 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 114
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
T C CRPG++ + + CV CA+ + C RC G RCEC G +LA
Sbjct: 115 LTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCM-HRCQVVRGLARCECHVGYQLAA 173
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-----AQSTVKSHXXXXXXXXX 292
D +C+D+DEC+ C++G C N G+++CVC GY + +
Sbjct: 174 DGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEA 232
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C H C +T CTC G+ L D R+C D+D+CA PC C N G Y C
Sbjct: 233 NNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS--PCCQQVCTNNPGGYEC 290
Query: 353 TCTDGLVPSAAGAKPTCQDIDECA 376
C G SA G C+D+DECA
Sbjct: 291 GCYAGYRLSADGC--GCEDVDECA 312
Score = 162 bits (393), Expect = 3e-39
Identities = 121/408 (29%), Positives = 160/408 (39%), Gaps = 46/408 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+ +N CA G C H + + C C PG++ CV + C +G C C
Sbjct: 96 LAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHR-C 154
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
G C C GY+ K C D+DECA A C G C+NT GSF+C C G EL
Sbjct: 155 QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELG 213
Query: 237 PD-----RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
D R+ + ++ C +G CS+G G C C GY T
Sbjct: 214 ADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPL-CTCPRGYELDT-DQRTCIDVDDC 271
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
CQ C N PG Y C C G+ L ADG C D+DECA C C N GS+
Sbjct: 272 ADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGSFQ 330
Query: 352 CTCTDG--LVPSAAGAKPTCQ---DIDECADLISTIIMMSV--DELQK-------SVDPQ 397
C+C G L G P + D+D + + ++V DEL + D +
Sbjct: 331 CSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEE 390
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
EL G H FVC D + +C L DC C L G
Sbjct: 391 EAELRGE---HTLTEKFVC-LDDSFG------------HDCSLTCDDCRNGGTC--LLGL 432
Query: 458 FQCRCRDGWRG--DGATC--EDVDECLTNNGGCHPRATCANTDGSFRC 501
C C +GW G TC + + + + C TC + G+ RC
Sbjct: 433 DGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC 480
Score = 148 bits (359), Expect = 5e-35
Identities = 96/276 (34%), Positives = 123/276 (44%), Gaps = 44/276 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
CQH CVNTPGSY C C+ G+ L D R+C I+ CA G C + T+ + C C
Sbjct: 67 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP 126
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G G C CA+ + + C G C
Sbjct: 127 GFQLQEDGRH--CVRRSPCANRNGSCMHR---------------------CQVVRGLARC 163
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATC- 473
+C GY + + G AC D DEC G C A C+N GSF+C C G+ DG C
Sbjct: 164 ECHVGYQLAAD-GKACEDVDECAAGLAQC--AHGCLNTQGSFKCVCHAGYELGADGRQCY 220
Query: 474 ----EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
E V+ C NNGGC C++T C C GY+ D RT C+D+D+C
Sbjct: 221 RIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDT-DQRT------CIDVDDC 271
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
A+ P C C+N PGGYEC C G+ +ADG C
Sbjct: 272 ADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGC 305
Score = 137 bits (331), Expect = 1e-31
Identities = 99/328 (30%), Positives = 137/328 (41%), Gaps = 43/328 (13%)
Query: 244 DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVN 303
D+DEC +G C + C N G+Y C C G+ T CQH CV
Sbjct: 56 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 114
Query: 304 TPGSYH-CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSA 362
+ H C CR G+ L+ DGR C CA C +C+ G C C G +A
Sbjct: 115 LTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLAA 173
Query: 363 AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGY 422
G C+D+DECA ++ C G C NT GSF C C GY
Sbjct: 174 DGK--ACEDVDECAAGLAQ--------------------CAHG-CLNTQGSFKCVCHAGY 210
Query: 423 SVKPEQGPACTDDDECELGTCDCHPAA---DCINLPGSFQCRCRDGWR--GDGATCEDVD 477
+ + G C + + +C+ + C + C C G+ D TC DVD
Sbjct: 211 ELGAD-GRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVD 269
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
+C ++ C + C N G + C C GY+ G C C D+DECA+ CE
Sbjct: 270 DC-ADSPCC--QQVCTNNPGGYECGCYAGYRLSADG-----C--GCEDVDECASSRGGCE 319
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
+ HC+N G ++C C+ G+ D R C
Sbjct: 320 H-HCTNLAGSFQCSCEAGYRLHEDRRGC 346
Score = 89.8 bits (213), Expect = 2e-17
Identities = 76/268 (28%), Positives = 102/268 (38%), Gaps = 43/268 (16%)
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGA 365
G Y C + + + G D+DEC C +C NT GSY C C G
Sbjct: 35 GCYPCHLGQAGYPVSAGDQRPDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSR 93
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN-----TIGSFVCQCPD 420
TC I+ CA G G C + TI CQC
Sbjct: 94 --TCLAINSCA-------------------------LGNGGCQHHCVQLTITRHRCQCRP 126
Query: 421 GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDE 478
G+ ++ E G C C C + G +C C G++ DG CEDVDE
Sbjct: 127 GFQLQ-EDGRHCVRRSPCANRNGSCMHRCQVVR--GLARCECHVGYQLAADGKACEDVDE 183
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN 538
C C C NT GSF+C+C GY+ G + C ++ C + C +
Sbjct: 184 CAAGLAQC--AHGCLNTQGSFKCVCHAGYELGADGRQ--CYRIEMEIVNSCEANNGGCSH 239
Query: 539 GHCSNTPGGYECDCDVGFTRAADGRSCL 566
G CS+T G C C G+ D R+C+
Sbjct: 240 G-CSHTSAGPLCTCPRGYELDTDQRTCI 266
Score = 68.1 bits (159), Expect = 8e-11
Identities = 99/411 (24%), Positives = 139/411 (33%), Gaps = 62/411 (15%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICV--DIDECADNDALCRGGRCVNTAGSFRCECGH-G 232
C + G C G++ +D + C + C G C G RC G G
Sbjct: 602 CDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTG 661
Query: 233 MELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ D + C C + A C+ + G C+C G+ S +
Sbjct: 662 EDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGP 719
Query: 292 XXXXRCQHSCVNT----PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTV 347
RC SC N P + HC+C GW G SC+ + C C +
Sbjct: 720 SCQTRC--SCANDGHCHPATGHCSCAPGW----TGFSCQRACDTGHWGPDCSH-PCNCSA 772
Query: 348 GSYTCTCTDGLVPSAAG-AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-- 404
G +C GL AG P C+ +C Q P + C
Sbjct: 773 GHGSCDAISGLCLCEAGYVGPRCEQ--QCP--------------QGHFGPGCEQRCQCQH 816
Query: 405 -GSCHNTIGSFVCQCPDGY--SVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR 461
+C + G+ C CP G+ + PA +C C+C A C + GS C
Sbjct: 817 GAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCR-SACNCTAGAACDAVNGS--CL 871
Query: 462 CRDGWRGDGAT--C--EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C G RG C DV ++GGC C G RCLC G+ GD
Sbjct: 872 CPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDK------ 923
Query: 518 CCVYSCVD---IDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C+ + CA + C + G C C GFT + + C
Sbjct: 924 -CQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQGC 971
Score = 60.9 bits (141), Expect = 1e-08
Identities = 106/460 (23%), Positives = 142/460 (30%), Gaps = 57/460 (12%)
Query: 129 CGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVN---ECEIVDGVCGDGD-CHNTEGSFT 184
CG C + G C C PG + C + C+ + C C G+
Sbjct: 641 CGGAPCHGVTG--QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA-- 696
Query: 185 CHCRPGYKADDFSKICVDI---DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
C C PG+ +C C + G C G C C G + +
Sbjct: 697 CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATG--HCSCAPGWTGFSCQRA 754
Query: 242 CKDID---ECSITSGICS--NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
C +CS CS +G+C+ G C+C+ GY + R
Sbjct: 755 CDTGHWGPDCSHPCN-CSAGHGSCDAISGL--CLCEAGYVGPRCEQQCPQGHFGPGCEQR 811
Query: 297 CQ--HSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
CQ H S CTC GW G C C G G CR+ C C
Sbjct: 812 CQCQHGAACDHVSGACTCPAGWR----GTFCEHA--CPAGFF---GLDCRSA-----CNC 857
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
T G A C + V ++ G C G
Sbjct: 858 TAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDV----RAGCRHSGGCLNGGLCDPHTGR- 912
Query: 415 VCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC 473
C CP G++ Q P E C C P A C ++ G+ CRC G+ G G C
Sbjct: 913 -CLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSG--C 967
Query: 474 EDVDECLTNNGGCHPRATCAN----TDGSFRCLCDTGYKGDGYGLRTVCCVY--SCVDID 527
E GC C N + C C TG+ G L + +C +
Sbjct: 968 EQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVC 1027
Query: 528 ECANDPTLCE--NGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C+ G C PG C+ G + G C
Sbjct: 1028 GCGQG-AACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGC 1066
Score = 56.0 bits (129), Expect = 3e-07
Identities = 110/456 (24%), Positives = 147/456 (32%), Gaps = 66/456 (14%)
Query: 130 GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVN---ECEIVDGVCGDGDCHNTEGSFTCH 186
GHG C + G C C GY C + CE C + G+ C
Sbjct: 773 GHGSCDAISG--LCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGA--CT 828
Query: 187 CRPGYKADDFSKICVDIDECADNDALCR---GGRCVNTAGSFRCECGHGMELAPDRLSCK 243
C G++ C D + C G C GS C G ++ +
Sbjct: 829 CPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPR 888
Query: 244 DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
D+ SG C NG C+ G +C+C G+ +S RC SC
Sbjct: 889 DVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRC--SCP 944
Query: 303 NTPGSYH----CTCREGWHLRADGRSCRDIDECAGGARPCG---GGQCRNTVGSYTCTCT 355
+H C C G+ + C G + CG GG C G+ C C
Sbjct: 945 PGAACHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCP 1002
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG---SCHNTIG 412
G + + TC Q P +CG G +C G
Sbjct: 1003 TGFLGTDCNL--TCP--------------------QGRFGPNCTHVCGCGQGAACDPVTG 1040
Query: 413 SFVCQCPDGYS-VKPEQG-PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
+ C CP G + V+ E+G P CE TC C C GS C C GW G
Sbjct: 1041 T--CLCPPGRAGVRCERGCPQNRFGVGCE-HTCSCRNGGLCHASNGS--CSCGLGWTGRH 1095
Query: 471 A--TCED--VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI 526
C CH +TC G+ C C G+ G R + +D
Sbjct: 1096 CELACPPGRYGAACHLECSCHNNSTCEPATGT--CRCGPGFYGQACEHRRSGATCN-LDC 1152
Query: 527 DECANDPTLCENGHCSNTPGGYECDCDVGFTRAADG 562
P+ C HC + GG +CD G DG
Sbjct: 1153 RRGQFGPS-C-TLHC-DCGGGADCDPVSGQCHCVDG 1185
Score = 51.6 bits (118), Expect = 7e-06
Identities = 109/428 (25%), Positives = 138/428 (32%), Gaps = 51/428 (11%)
Query: 152 DSKNHTC-VDVNECEIVDGVC--GDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECAD 208
DS H C + ++C G C G C EG C D F K C C +
Sbjct: 409 DSFGHDCSLTCDDCRN-GGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQN 467
Query: 209 NDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDE-CSITSGICSNGACENQMGTY 267
GG C + G+ RC G D + C + G C G
Sbjct: 468 ------GGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA- 520
Query: 268 QCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREG-WHLRADGRSCR 326
C+CD G CQ CV P + C R+G +A R R
Sbjct: 521 -CLCDPGLYGRFCHLTCPPWAFGPGCSEECQ--CVQ-PHTQSCDKRDGSCSCKAGFRGER 576
Query: 327 DIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAKPTCQDI-DECADLISTIIM 384
EC G G Q C VG C G A +D EC + T
Sbjct: 577 CQAECELGYFGPGCWQACTCPVG-VACDSVSGECGKRCPAGFQGEDCGQECP--VGTF-- 631
Query: 385 MSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCD 444
V+ CG CH G C+CP G + E A + LG +
Sbjct: 632 --------GVNCSSSCSCGGAPCHGVTGQ--CRCPPGRT--GEDCEADCPEGRWGLGCQE 679
Query: 445 ----CHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFR 500
C AA C P + C C G+ G + C+DV C R +CAN DG
Sbjct: 680 ICPACQHAARCD--PETGACLCLPGFVG--SRCQDVCPAGWYGPSCQTRCSCAN-DG--H 732
Query: 501 CLCDTGYKGDGYGLRTVCCVYSCVDIDECAND---PTLCENGHCSNTPGGYECDCDVGFT 557
C TG+ G C +C D D P C GH S C C+ G+
Sbjct: 733 CHPATGHCSCAPGWTGFSCQRAC-DTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYV 791
Query: 558 RAADGRSC 565
+ C
Sbjct: 792 GPRCEQQC 799
Score = 38.7 bits (86), Expect = 0.054
Identities = 89/367 (24%), Positives = 114/367 (31%), Gaps = 50/367 (13%)
Query: 129 CGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV--DVNE-CEIVDGVCGDGDCHNTEGSFTC 185
C G + + G +C C G C+ DV C G G C G C
Sbjct: 857 CTAGAACDAVNG-SCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTGR--C 913
Query: 186 HCRPGYKADDFSKICVDI---DECADNDALCRGGRCVNTAGSFRCE---CGHGMELA--P 237
C G+ D C+ + CA + G C + G+ RC G G E P
Sbjct: 914 LCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQGCPP 973
Query: 238 DRLS--CKDIDECSITSGIC--SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
R C+ + C + G C + GAC G C+ Q +
Sbjct: 974 GRYGPGCEQLCGC-LNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQG 1032
Query: 294 XXRCQH---SCVNTPGSYHCTCREGWHLRADGRSCRDIDECA-GGARPCGGGQCRNTVGS 349
C +C+ PG C G G C C GG G C +G
Sbjct: 1033 AA-CDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGW 1091
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
C P GA C C + S E P G H
Sbjct: 1092 TGRHCELACPPGRYGA--ACHLECSCHN-------NSTCEPATGTCRCGPGFYGQACEHR 1142
Query: 410 TIGSFV-CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG 468
G+ C G + GP+CT CDC ADC P S QC C DG+
Sbjct: 1143 RSGATCNLDCRRG-----QFGPSCTLH-------CDCGGGADCD--PVSGQCHCVDGYM- 1187
Query: 469 DGATCED 475
G TC +
Sbjct: 1188 -GPTCRE 1193
>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 191 bits (465), Expect = 7e-48
Identities = 111/331 (33%), Positives = 153/331 (46%), Gaps = 30/331 (9%)
Query: 181 GSFTCHC-RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDR 239
G + CH + GY + D+DEC ++ C+ RCVNT GS+ CEC G L D
Sbjct: 35 GCYPCHLGQAGYPVSAGDQR-PDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDS 92
Query: 240 LSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
+C I+ C++ +G C + + + ++C C G+ H C H
Sbjct: 93 RTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH 152
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C G C C G+ L ADG++C D+DECA G C G C NT GS+ C C G
Sbjct: 153 RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYE 211
Query: 360 PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCP 419
A G + C I+ M V+ + + C G H + G +C CP
Sbjct: 212 LGADGRQ--CYRIE----------MEIVNSCEANNGG-----CSHGCSHTSAGP-LCTCP 253
Query: 420 DGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVD 477
GY + +Q C D D+C C C C N PG ++C C G+R DG CEDVD
Sbjct: 254 RGYELDTDQR-TCIDVDDCADSPC-CQQV--CTNNPGGYECGCYAGYRLSADGCGCEDVD 309
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
EC ++ GGC C N GSF+C C+ GY+
Sbjct: 310 ECASSRGGCEHH--CTNLAGSFQCSCEAGYR 338
Score = 178 bits (433), Expect = 5e-44
Identities = 91/264 (34%), Positives = 127/264 (48%), Gaps = 12/264 (4%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC G C H RC N G + C+C PG+ + + TC+ +N C + +G C
Sbjct: 56 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 114
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
T C CRPG++ + + CV CA+ + C RC G RCEC G +LA
Sbjct: 115 LTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCM-HRCQVVRGLARCECHVGYQLAA 173
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-----AQSTVKSHXXXXXXXXX 292
D +C+D+DEC+ C++G C N G+++CVC GY + +
Sbjct: 174 DGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEA 232
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C H C +T CTC G+ L D R+C D+D+CA PC C N G Y C
Sbjct: 233 NNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS--PCCQQVCTNNPGGYEC 290
Query: 353 TCTDGLVPSAAGAKPTCQDIDECA 376
C G SA G C+D+DECA
Sbjct: 291 GCYAGYRLSADGC--GCEDVDECA 312
Score = 162 bits (393), Expect = 3e-39
Identities = 121/408 (29%), Positives = 160/408 (39%), Gaps = 46/408 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+ +N CA G C H + + C C PG++ CV + C +G C C
Sbjct: 96 LAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHR-C 154
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
G C C GY+ K C D+DECA A C G C+NT GSF+C C G EL
Sbjct: 155 QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELG 213
Query: 237 PD-----RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
D R+ + ++ C +G CS+G G C C GY T
Sbjct: 214 ADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPL-CTCPRGYELDT-DQRTCIDVDDC 271
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
CQ C N PG Y C C G+ L ADG C D+DECA C C N GS+
Sbjct: 272 ADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGSFQ 330
Query: 352 CTCTDG--LVPSAAGAKPTCQ---DIDECADLISTIIMMSV--DELQK-------SVDPQ 397
C+C G L G P + D+D + + ++V DEL + D +
Sbjct: 331 CSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEE 390
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
EL G H FVC D + +C L DC C L G
Sbjct: 391 EAELRGE---HTLTEKFVC-LDDSFG------------HDCSLTCDDCRNGGTC--LLGL 432
Query: 458 FQCRCRDGWRG--DGATC--EDVDECLTNNGGCHPRATCANTDGSFRC 501
C C +GW G TC + + + + C TC + G+ RC
Sbjct: 433 DGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC 480
Score = 148 bits (359), Expect = 5e-35
Identities = 96/276 (34%), Positives = 123/276 (44%), Gaps = 44/276 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
CQH CVNTPGSY C C+ G+ L D R+C I+ CA G C + T+ + C C
Sbjct: 67 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP 126
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G G C CA+ + + C G C
Sbjct: 127 GFQLQEDGRH--CVRRSPCANRNGSCMHR---------------------CQVVRGLARC 163
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATC- 473
+C GY + + G AC D DEC G C A C+N GSF+C C G+ DG C
Sbjct: 164 ECHVGYQLAAD-GKACEDVDECAAGLAQC--AHGCLNTQGSFKCVCHAGYELGADGRQCY 220
Query: 474 ----EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
E V+ C NNGGC C++T C C GY+ D RT C+D+D+C
Sbjct: 221 RIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDT-DQRT------CIDVDDC 271
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
A+ P C C+N PGGYEC C G+ +ADG C
Sbjct: 272 ADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGC 305
Score = 137 bits (331), Expect = 1e-31
Identities = 99/328 (30%), Positives = 137/328 (41%), Gaps = 43/328 (13%)
Query: 244 DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVN 303
D+DEC +G C + C N G+Y C C G+ T CQH CV
Sbjct: 56 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 114
Query: 304 TPGSYH-CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSA 362
+ H C CR G+ L+ DGR C CA C +C+ G C C G +A
Sbjct: 115 LTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLAA 173
Query: 363 AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGY 422
G C+D+DECA ++ C G C NT GSF C C GY
Sbjct: 174 DGK--ACEDVDECAAGLAQ--------------------CAHG-CLNTQGSFKCVCHAGY 210
Query: 423 SVKPEQGPACTDDDECELGTCDCHPAA---DCINLPGSFQCRCRDGWR--GDGATCEDVD 477
+ + G C + + +C+ + C + C C G+ D TC DVD
Sbjct: 211 ELGAD-GRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVD 269
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
+C ++ C + C N G + C C GY+ G C C D+DECA+ CE
Sbjct: 270 DC-ADSPCC--QQVCTNNPGGYECGCYAGYRLSADG-----C--GCEDVDECASSRGGCE 319
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
+ HC+N G ++C C+ G+ D R C
Sbjct: 320 H-HCTNLAGSFQCSCEAGYRLHEDRRGC 346
Score = 89.8 bits (213), Expect = 2e-17
Identities = 76/268 (28%), Positives = 102/268 (38%), Gaps = 43/268 (16%)
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGA 365
G Y C + + + G D+DEC C +C NT GSY C C G
Sbjct: 35 GCYPCHLGQAGYPVSAGDQRPDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSR 93
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN-----TIGSFVCQCPD 420
TC I+ CA G G C + TI CQC
Sbjct: 94 --TCLAINSCA-------------------------LGNGGCQHHCVQLTITRHRCQCRP 126
Query: 421 GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDE 478
G+ ++ E G C C C + G +C C G++ DG CEDVDE
Sbjct: 127 GFQLQ-EDGRHCVRRSPCANRNGSCMHRCQVVR--GLARCECHVGYQLAADGKACEDVDE 183
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN 538
C C C NT GSF+C+C GY+ G + C ++ C + C +
Sbjct: 184 CAAGLAQC--AHGCLNTQGSFKCVCHAGYELGADGRQ--CYRIEMEIVNSCEANNGGCSH 239
Query: 539 GHCSNTPGGYECDCDVGFTRAADGRSCL 566
G CS+T G C C G+ D R+C+
Sbjct: 240 G-CSHTSAGPLCTCPRGYELDTDQRTCI 266
Score = 68.1 bits (159), Expect = 8e-11
Identities = 99/411 (24%), Positives = 139/411 (33%), Gaps = 62/411 (15%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICV--DIDECADNDALCRGGRCVNTAGSFRCECGH-G 232
C + G C G++ +D + C + C G C G RC G G
Sbjct: 602 CDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTG 661
Query: 233 MELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ D + C C + A C+ + G C+C G+ S +
Sbjct: 662 EDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGP 719
Query: 292 XXXXRCQHSCVNT----PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTV 347
RC SC N P + HC+C GW G SC+ + C C +
Sbjct: 720 SCQTRC--SCANDGHCHPATGHCSCAPGW----TGFSCQRACDTGHWGPDCSH-PCNCSA 772
Query: 348 GSYTCTCTDGLVPSAAG-AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-- 404
G +C GL AG P C+ +C Q P + C
Sbjct: 773 GHGSCDAISGLCLCEAGYVGPRCEQ--QCP--------------QGHFGPGCEQRCQCQH 816
Query: 405 -GSCHNTIGSFVCQCPDGY--SVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR 461
+C + G+ C CP G+ + PA +C C+C A C + GS C
Sbjct: 817 GAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCR-SACNCTAGAACDAVNGS--CL 871
Query: 462 CRDGWRGDGAT--C--EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C G RG C DV ++GGC C G RCLC G+ GD
Sbjct: 872 CPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDK------ 923
Query: 518 CCVYSCVD---IDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C+ + CA + C + G C C GFT + + C
Sbjct: 924 -CQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQGC 971
Score = 60.9 bits (141), Expect = 1e-08
Identities = 106/460 (23%), Positives = 142/460 (30%), Gaps = 57/460 (12%)
Query: 129 CGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVN---ECEIVDGVCGDGD-CHNTEGSFT 184
CG C + G C C PG + C + C+ + C C G+
Sbjct: 641 CGGAPCHGVTG--QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA-- 696
Query: 185 CHCRPGYKADDFSKICVDI---DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
C C PG+ +C C + G C G C C G + +
Sbjct: 697 CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATG--HCSCAPGWTGFSCQRA 754
Query: 242 CKDID---ECSITSGICS--NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
C +CS CS +G+C+ G C+C+ GY + R
Sbjct: 755 CDTGHWGPDCSHPCN-CSAGHGSCDAISGL--CLCEAGYVGPRCEQQCPQGHFGPGCEQR 811
Query: 297 CQ--HSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
CQ H S CTC GW G C C G G CR+ C C
Sbjct: 812 CQCQHGAACDHVSGACTCPAGWR----GTFCEHA--CPAGFF---GLDCRSA-----CNC 857
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
T G A C + V ++ G C G
Sbjct: 858 TAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDV----RAGCRHSGGCLNGGLCDPHTGR- 912
Query: 415 VCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC 473
C CP G++ Q P E C C P A C ++ G+ CRC G+ G G C
Sbjct: 913 -CLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSG--C 967
Query: 474 EDVDECLTNNGGCHPRATCAN----TDGSFRCLCDTGYKGDGYGLRTVCCVY--SCVDID 527
E GC C N + C C TG+ G L + +C +
Sbjct: 968 EQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVC 1027
Query: 528 ECANDPTLCE--NGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C+ G C PG C+ G + G C
Sbjct: 1028 GCGQG-AACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGC 1066
Score = 56.0 bits (129), Expect = 3e-07
Identities = 110/456 (24%), Positives = 147/456 (32%), Gaps = 66/456 (14%)
Query: 130 GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVN---ECEIVDGVCGDGDCHNTEGSFTCH 186
GHG C + G C C GY C + CE C + G+ C
Sbjct: 773 GHGSCDAISG--LCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGA--CT 828
Query: 187 CRPGYKADDFSKICVDIDECADNDALCR---GGRCVNTAGSFRCECGHGMELAPDRLSCK 243
C G++ C D + C G C GS C G ++ +
Sbjct: 829 CPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPR 888
Query: 244 DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
D+ SG C NG C+ G +C+C G+ +S RC SC
Sbjct: 889 DVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRC--SCP 944
Query: 303 NTPGSYH----CTCREGWHLRADGRSCRDIDECAGGARPCG---GGQCRNTVGSYTCTCT 355
+H C C G+ + C G + CG GG C G+ C C
Sbjct: 945 PGAACHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCP 1002
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG---SCHNTIG 412
G + + TC Q P +CG G +C G
Sbjct: 1003 TGFLGTDCNL--TCP--------------------QGRFGPNCTHVCGCGQGAACDPVTG 1040
Query: 413 SFVCQCPDGYS-VKPEQG-PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
+ C CP G + V+ E+G P CE TC C C GS C C GW G
Sbjct: 1041 T--CLCPPGRAGVRCERGCPQNRFGVGCE-HTCSCRNGGLCHASNGS--CSCGLGWTGRH 1095
Query: 471 A--TCED--VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI 526
C CH +TC G+ C C G+ G R + +D
Sbjct: 1096 CELACPPGRYGAACHLECSCHNNSTCEPATGT--CRCGPGFYGQACEHRRSGATCN-LDC 1152
Query: 527 DECANDPTLCENGHCSNTPGGYECDCDVGFTRAADG 562
P+ C HC + GG +CD G DG
Sbjct: 1153 RRGQFGPS-C-TLHC-DCGGGADCDPVSGQCHCVDG 1185
Score = 51.6 bits (118), Expect = 7e-06
Identities = 109/428 (25%), Positives = 138/428 (32%), Gaps = 51/428 (11%)
Query: 152 DSKNHTC-VDVNECEIVDGVC--GDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECAD 208
DS H C + ++C G C G C EG C D F K C C +
Sbjct: 409 DSFGHDCSLTCDDCRN-GGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQN 467
Query: 209 NDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDE-CSITSGICSNGACENQMGTY 267
GG C + G+ RC G D + C + G C G
Sbjct: 468 ------GGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA- 520
Query: 268 QCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREG-WHLRADGRSCR 326
C+CD G CQ CV P + C R+G +A R R
Sbjct: 521 -CLCDPGLYGRFCHLTCPPWAFGPGCSEECQ--CVQ-PHTQSCDKRDGSCSCKAGFRGER 576
Query: 327 DIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAKPTCQDI-DECADLISTIIM 384
EC G G Q C VG C G A +D EC + T
Sbjct: 577 CQAECELGYFGPGCWQACTCPVG-VACDSVSGECGKRCPAGFQGEDCGQECP--VGTF-- 631
Query: 385 MSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCD 444
V+ CG CH G C+CP G + E A + LG +
Sbjct: 632 --------GVNCSSSCSCGGAPCHGVTGQ--CRCPPGRT--GEDCEADCPEGRWGLGCQE 679
Query: 445 ----CHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFR 500
C AA C P + C C G+ G + C+DV C R +CAN DG
Sbjct: 680 ICPACQHAARCD--PETGACLCLPGFVG--SRCQDVCPAGWYGPSCQTRCSCAN-DG--H 732
Query: 501 CLCDTGYKGDGYGLRTVCCVYSCVDIDECAND---PTLCENGHCSNTPGGYECDCDVGFT 557
C TG+ G C +C D D P C GH S C C+ G+
Sbjct: 733 CHPATGHCSCAPGWTGFSCQRAC-DTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYV 791
Query: 558 RAADGRSC 565
+ C
Sbjct: 792 GPRCEQQC 799
Score = 38.7 bits (86), Expect = 0.054
Identities = 89/367 (24%), Positives = 114/367 (31%), Gaps = 50/367 (13%)
Query: 129 CGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV--DVNE-CEIVDGVCGDGDCHNTEGSFTC 185
C G + + G +C C G C+ DV C G G C G C
Sbjct: 857 CTAGAACDAVNG-SCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTGR--C 913
Query: 186 HCRPGYKADDFSKICVDI---DECADNDALCRGGRCVNTAGSFRCE---CGHGMELA--P 237
C G+ D C+ + CA + G C + G+ RC G G E P
Sbjct: 914 LCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQGCPP 973
Query: 238 DRLS--CKDIDECSITSGIC--SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
R C+ + C + G C + GAC G C+ Q +
Sbjct: 974 GRYGPGCEQLCGC-LNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQG 1032
Query: 294 XXRCQH---SCVNTPGSYHCTCREGWHLRADGRSCRDIDECA-GGARPCGGGQCRNTVGS 349
C +C+ PG C G G C C GG G C +G
Sbjct: 1033 AA-CDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGW 1091
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
C P GA C C + S E P G H
Sbjct: 1092 TGRHCELACPPGRYGA--ACHLECSCHN-------NSTCEPATGTCRCGPGFYGQACEHR 1142
Query: 410 TIGSFV-CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG 468
G+ C G + GP+CT CDC ADC P S QC C DG+
Sbjct: 1143 RSGATCNLDCRRG-----QFGPSCTLH-------CDCGGGADCD--PVSGQCHCVDGYM- 1187
Query: 469 DGATCED 475
G TC +
Sbjct: 1188 -GPTCRE 1193
>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 191 bits (465), Expect = 7e-48
Identities = 149/463 (32%), Positives = 200/463 (43%), Gaps = 70/463 (15%)
Query: 120 NECAAFPGLCGHGRCRNL-LGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCH 177
N C P G G C L L + C C PG+ S C + C C +G C
Sbjct: 104 NACLTNPCRNG-GTCDLLTLTEYKCRCPPGWSGKS----CQQADPC--ASNPCANGGQCL 156
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELA 236
E S+ CHC P + + D++EC LCR GG C N GS+RC C
Sbjct: 157 PFEASYICHCPPSFHGPTCRQ---DVNECGQKPGLCRHGGTCHNEVGSYRCVC-RATHTG 212
Query: 237 PDRLSC-KDIDECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
P+ C + CS + C NG G T++C C G+ + +
Sbjct: 213 PN---CERPYVPCSPSP--CQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGN--- 264
Query: 294 XXRCQH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGS 349
C++ +CV+ +Y+C C W G+ C D+DEC C GG C NT G
Sbjct: 265 --NCKNGGACVDGVNTYNCRCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGG 318
Query: 350 YTCTCTDGLVPSAAG------AKPTCQDIDECADLISTIIMMS----VDELQKSVDPQIP 399
Y C C +G A C C D +++ L D I
Sbjct: 319 YNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS 378
Query: 400 ELCGAGS-CH-NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLP 455
C GS C N + G +C CP GY+ GPAC+ D DEC LG C A CIN
Sbjct: 379 NPCNEGSNCDTNPVNGKAICTCPSGYT-----GPACSQDVDECSLGANPCEHAGKCINTL 433
Query: 456 GSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
GSF+C+C G+ G CE DV+EC++N C ATC + G F+C+C GY+G
Sbjct: 434 GSFECQCLQGY--TGPRCEIDVNECVSN--PCQNDATCLDQIGEFQCICMPGYEG----- 484
Query: 515 RTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
V+ V+ DECA+ P L NG C + ++C+C GFT
Sbjct: 485 -----VHCEVNTDECASSPCL-HNGRCLDKINEFQCECPTGFT 521
Score = 182 bits (443), Expect = 3e-45
Identities = 142/466 (30%), Positives = 205/466 (43%), Gaps = 77/466 (16%)
Query: 118 EVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGD 175
+V+EC+ C H G+C N LG F C C GY +DVNEC V C D
Sbjct: 412 DVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCE---IDVNEC--VSNPCQNDAT 466
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C + G F C C PGY+ V+ DECA + L GRC++ F+CEC G
Sbjct: 467 CLDQIGEFQCICMPGYEGVHCE---VNTDECASSPCL-HNGRCLDKINEFQCECPTGFT- 521
Query: 236 APDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
L D+DEC+ T C NGA C + TY CVC EGY + +
Sbjct: 522 --GHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGYTGTHCE-----VDIDECDP 572
Query: 295 XRCQH-SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYT 351
C + SC + ++ C CR G+ G C +I+EC+ ++PC GG C++ +Y
Sbjct: 573 DPCHYGSCKDGVATFTCLCRPGY----TGHHCETNINECS--SQPCRHGGTCQDRDNAYL 626
Query: 352 CTCTDGLVPSAAGAKPTCQ-DIDECAD--LISTIIMMSVDELQKSVDP---------QIP 399
C C G P C+ ++D+CA S + +D + + +P I
Sbjct: 627 CFCLKGTTG------PNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINID 680
Query: 400 ELCG-----AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCIN 453
E G G+C + I F C+CP+GY P C + +EC C D +N
Sbjct: 681 ECAGNPCHNGGTCEDGINGFTCRCPEGY-----HDPTCLSEVNECNSNPCVHGACRDSLN 735
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
++C C GW G + +EC +N C TC + + C C G+ G
Sbjct: 736 ---GYKCDCDPGWSGTNCDINN-NECESNP--CVNGGTCKDMTSGYVCTCREGFSGPN-- 787
Query: 514 LRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRA 559
C +I+ECA++P L G C + GY+C+C + +T A
Sbjct: 788 -----CQ---TNINECASNPCL-NQGTCIDDVAGYKCNCLLPYTGA 824
Score = 172 bits (418), Expect = 3e-42
Identities = 137/453 (30%), Positives = 191/453 (42%), Gaps = 80/453 (17%)
Query: 116 QMEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC PGLC H G C N +G + C C + + V + +G G
Sbjct: 176 RQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNG----G 231
Query: 175 DCHNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C T + + C C PG+ + + +ID+C N+ GG CV+ ++ C C
Sbjct: 232 TCRPTGDVTHECACLPGFTGQNCEE---NIDDCPGNNCK-NGGACVDGVNTYNCRCPPEW 287
Query: 234 ELAPDRLSCKDIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+ +D+DEC + C N G C N G Y CVC G+ +
Sbjct: 288 ---TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAA- 343
Query: 293 XXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQC-RNTV- 347
C H +C + S++C C G G C D C + PC G C N V
Sbjct: 344 ----CFHGATCHDRVASFYCECPHG----RTGLLCHLNDACI--SNPCNEGSNCDTNPVN 393
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
G CTC G A QD+DEC+ + + + AG C
Sbjct: 394 GKAICTCPSGYTGPACS-----QDVDECS--------LGANPCEH-----------AGKC 429
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
NT+GSF CQC GY+ GP C D +EC + C A C++ G FQC C G+
Sbjct: 430 INTLGSFECQCLQGYT-----GPRCEIDVNECV--SNPCQNDATCLDQIGEFQCICMPGY 482
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+G CE + DEC ++ C C + F+C C TG+ G C Y D
Sbjct: 483 --EGVHCEVNTDECASS--PCLHNGRCLDKINEFQCECPTGFTGH-------LCQY---D 528
Query: 526 IDECANDPTLCENG-HCSNTPGGYECDCDVGFT 557
+DECA+ P C+NG C + P Y C C G+T
Sbjct: 529 VDECASTP--CKNGAKCLDGPNTYTCVCTEGYT 559
Score = 159 bits (386), Expect = 2e-38
Identities = 128/448 (28%), Positives = 194/448 (43%), Gaps = 68/448 (15%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPG 190
G C + + + C C P + + + DV+EC+++ C +G CHNT G + C C G
Sbjct: 270 GACVDGVNTYNCRCPPEW---TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNG 326
Query: 191 YKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSI 250
+ +D S+ +ID+CA + A G C + SF CEC HG L C D C
Sbjct: 327 WTGEDCSE---NIDDCA-SAACFHGATCHDRVASFYCECPHGRT----GLLCHLNDAC-- 376
Query: 251 TSGICSNGA-CENQM--GTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTP 305
S C+ G+ C+ G C C GY T + C+H+ C+NT
Sbjct: 377 ISNPCNEGSNCDTNPVNGKAICTCPSGY---TGPACSQDVDECSLGANPCEHAGKCINTL 433
Query: 306 GSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGL----- 358
GS+ C C +G+ G C D++EC + PC C + +G + C C G
Sbjct: 434 GSFECQCLQGY----TGPRCEIDVNECV--SNPCQNDATCLDQIGEFQCICMPGYEGVHC 487
Query: 359 -VPSAAGAKPTCQDIDECADLISTIIM-----MSVDELQKSVDPQIPELCGAGS-CHNTI 411
V + A C C D I+ + Q VD C G+ C +
Sbjct: 488 EVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGP 547
Query: 412 GSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
++ C C +GY+ G C D DEC+ C D + +F C CR G+ G
Sbjct: 548 NTYTCVCTEGYT-----GTHCEVDIDECDPDPCHYGSCKDGV---ATFTCLCRPGYTGHH 599
Query: 471 ATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
CE +++EC ++ C TC + D ++ C C G G C +++D+C
Sbjct: 600 --CETNINEC--SSQPCRHGGTCQDRDNAYLCFCLKGTTGPN-------CE---INLDDC 645
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFT 557
A+ P C++G C + GYEC C+ G+T
Sbjct: 646 ASSP--CDSGTCLDKIDGYECACEPGYT 671
Score = 158 bits (384), Expect = 4e-38
Identities = 140/451 (31%), Positives = 192/451 (42%), Gaps = 87/451 (19%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
EVNEC + P C HG CR+ L G+ CDC PG+ S + ++ NECE V G G C
Sbjct: 716 EVNECNSNP--CVHGACRDSLNGYKCDCDPGW---SGTNCDINNNECESNPCVNG-GTCK 769
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
+ + C CR G+ + +I+ECA N L G C++ ++C C L P
Sbjct: 770 DMTSGYVCTCREGFSGPNCQ---TNINECASNPCL-NQGTCIDDVAGYKCNC-----LLP 820
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQ---CVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ ++ C NG Q Y+ CVC G+ T +
Sbjct: 821 YTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCE-----VDINECVL 875
Query: 295 XRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C+H SC NT G Y C C+ G+ GR+C DID+C PC GG C + + +
Sbjct: 876 SPCRHGASCQNTHGGYRCHCQAGY----SGRNCETDIDDCR--PNPCHNGGSCTDGINTA 929
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHN 409
C C G + +DI+ECA DP C G +C +
Sbjct: 930 FCDCLPGFRGTFCE-----EDINECAS-----------------DP-----CRNGANCTD 962
Query: 410 TIGSFVCQCPDGYS-VKPEQG-PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR 467
+ S+ C CP G+S + E P CT+ GTC D IN SF C C G+
Sbjct: 963 CVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTC-----VDGIN---SFTCLCPPGF- 1013
Query: 468 GDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI 526
G+ C+ DV+EC ++ C TC + GS+RC C GY G V+ C D
Sbjct: 1014 -TGSYCQHDVNEC--DSQPCLHGGTCQDGCGSYRCTCPQGYTGP----NCQNLVHWC-DS 1065
Query: 527 DECANDPTLCENGHCSNTPGGYECDCDVGFT 557
C N G C T Y C+C G+T
Sbjct: 1066 SPCKN------GGKCWQTHTQYRCECPSGWT 1090
Score = 153 bits (372), Expect = 1e-36
Identities = 130/465 (27%), Positives = 192/465 (41%), Gaps = 68/465 (14%)
Query: 122 CAAFPGLCGHGRCRNL--LGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG-DCH 177
CA P G G CR F+C C G++ TC VD+NEC + C G C
Sbjct: 833 CAPSPCRNG-GECRQSEDYESFSCVCPTGWQ----GQTCEVDINECVL--SPCRHGASCQ 885
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT G + CHC+ GY + DID+C N GG C + + C+C G
Sbjct: 886 NTHGGYRCHCQAGYSGRNCE---TDIDDCRPNPCH-NGGSCTDGINTAFCDCLPGFR--- 938
Query: 238 DRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+DI+EC+ S C NGA C + + +Y C C G++ +++
Sbjct: 939 GTFCEEDINECA--SDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG 996
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTC 354
+CV+ S+ C C G+ G C+ D++EC ++PC GG C++ GSY CTC
Sbjct: 997 ---TCVDGINSFTCLCPPGF----TGSYCQHDVNEC--DSQPCLHGGTCQDGCGSYRCTC 1047
Query: 355 TDGLV--------------PSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKS 393
G P G K C+ L + +S + +
Sbjct: 1048 PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQR 1107
Query: 394 VDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADC 451
+ LC G C + + C+C GY+ G C D DEC C A C
Sbjct: 1108 QGVDVARLCQHGGLCVDAGNTHHCRCQAGYT-----GSYCEDLVDECS--PSPCQNGATC 1160
Query: 452 INLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG 511
+ G + C+C G+ G + E++DECL++ C TC + +++C C G +G
Sbjct: 1161 TDYLGGYSCKCVAGYHGVNCS-EEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQGVH 1217
Query: 512 YGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
+ C +D + P NG C + GGY C C GF
Sbjct: 1218 CEINVDDCN---PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGF 1259
Score = 149 bits (362), Expect = 2e-35
Identities = 120/428 (28%), Positives = 176/428 (41%), Gaps = 66/428 (15%)
Query: 118 EVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++NECA+ P C +G C + + +TC C G+ + D E +G G C
Sbjct: 945 DINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG----GTC 998
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
+ SFTC C PG+ S D++EC D+ GG C + GS+RC C G
Sbjct: 999 VDGINSFTCLCPPGFTG---SYCQHDVNEC-DSQPCLHGGTCQDGCGSYRCTCPQGYT-G 1053
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ-----STVKSHXXXXXXXX 291
P+ C+++ +S + G C Y+C C G+ +V
Sbjct: 1054 PN---CQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGV 1110
Query: 292 XXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPC-GGGQCRNTV 347
CQH CV+ ++HC C+ G+ G C D +DEC+ PC G C + +
Sbjct: 1111 DVARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDLVDECSPS--PCQNGATCTDYL 1164
Query: 348 GSYTCTCTDGLVPSAAGAK------PTCQDIDECADLISTI------------IMMSVDE 389
G Y+C C G + CQ+ C DL +T ++VD+
Sbjct: 1165 GGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDD 1224
Query: 390 LQKSVDP--QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCH 446
VDP + P+ G+C + +G + C CP G+ G C D +EC CD
Sbjct: 1225 CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV-----GERCEGDVNECLSNPCDAR 1279
Query: 447 PAADCINLPGSFQCRCRDGWRGDGATCEDV-DEC----LTNNGGCHPRATCANTDGSFRC 501
+C+ F C CR G G CE V + C N G C A +NT F C
Sbjct: 1280 GTQNCVQRVNDFHCECRAG--HTGRRCESVINGCKGKPCKNGGTC---AVASNTARGFIC 1334
Query: 502 LCDTGYKG 509
C G++G
Sbjct: 1335 KCPAGFEG 1342
Score = 147 bits (356), Expect = 1e-34
Identities = 132/481 (27%), Positives = 200/481 (41%), Gaps = 112/481 (23%)
Query: 119 VNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG--- 174
+++CA+ C HG C + + F C+C G + +N+ + C +G
Sbjct: 336 IDDCAS--AACFHGATCHDRVASFYCECPHG-----RTGLLCHLNDA-CISNPCNEGSNC 387
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGM 233
D + G C C GY S+ D+DEC+ C G+C+NT GSF C+C G
Sbjct: 388 DTNPVNGKAICTCPSGYTGPACSQ---DVDECSLGANPCEHAGKCINTLGSFECQCLQGY 444
Query: 234 ELAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
P C+ D++EC S C N A C +Q+G +QC+C GY + +
Sbjct: 445 T-GP---RCEIDVNEC--VSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSP 498
Query: 292 XXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTV 347
C H+ C++ + C C G+ G C+ D+DECA + PC G +C +
Sbjct: 499 -----CLHNGRCLDKINEFQCECPTGF----TGHLCQYDVDECA--STPCKNGAKCLDGP 547
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
+YTC CT+G + DIDEC P+ C GSC
Sbjct: 548 NTYTCVCTEGYTGTHCEV-----DIDECD----------------------PDPCHYGSC 580
Query: 408 HNTIGSFVCQCPDGY------------SVKP-EQGPACTDDD--------------ECEL 440
+ + +F C C GY S +P G C D D CE+
Sbjct: 581 KDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI 640
Query: 441 GTCDCH----PAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTD 496
DC + C++ ++C C G+ G ++DEC N CH TC +
Sbjct: 641 NLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNI-NIDECAGN--PCHNGGTCEDGI 697
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
F C C GY C+ +++EC ++P C +G C ++ GY+CDCD G+
Sbjct: 698 NGFTCRCPEGY-------HDPTCL---SEVNECNSNP--CVHGACRDSLNGYKCDCDPGW 745
Query: 557 T 557
+
Sbjct: 746 S 746
Score = 138 bits (334), Expect = 5e-32
Identities = 127/485 (26%), Positives = 199/485 (41%), Gaps = 82/485 (16%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
++++NEC P C HG C+N GG+ C C GY S + D+++C C +G
Sbjct: 867 EVDINECVLSP--CRHGASCQNTHGGYRCHCQAGY---SGRNCETDIDDCR--PNPCHNG 919
Query: 175 -DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PG++ + DI+ECA +D G C + S+ C C G
Sbjct: 920 GSCTDGINTAFCDCLPGFRGTFCEE---DINECA-SDPCRNGANCTDCVDSYTCTCPAGF 975
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX-X 292
+ D E S +G G C + + ++ C+C G+ S +
Sbjct: 976 SGIHCENNTPDCTESSCFNG----GTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCL 1031
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQCRNTVGSYT 351
CQ C GSY CTC +G+ G +C+++ + PC GG+C T Y
Sbjct: 1032 HGGTCQDGC----GSYRCTCPQGY----TGPNCQNLVHWCDSS-PCKNGGKCWQTHTQYR 1082
Query: 352 CTCTDGL------VPSAA----------GAKPTCQDIDECADLISTIIMM-----SVDEL 390
C C G VPS + CQ C D +T +
Sbjct: 1083 CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYC 1142
Query: 391 QKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
+ VD P C G+ C + +G + C+C GY G C+++ DEC + C
Sbjct: 1143 EDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY-----HGVNCSEEIDECL--SHPCQNG 1195
Query: 449 ADCINLPGSFQCRCRDGWRGDGATCE-DVDEC------LTNNGGCHPRATCANTDGSFRC 501
C++LP +++C C G +G CE +VD+C ++ + C TC + G + C
Sbjct: 1196 GTCLDLPNTYKCSCPRGTQG--VHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC 1253
Query: 502 LCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGFTRAA 560
C G+ G+ C D++EC ++P +C + C+C G T
Sbjct: 1254 TCPPGFVGER-------CE---GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT--- 1300
Query: 561 DGRSC 565
GR C
Sbjct: 1301 -GRRC 1304
Score = 118 bits (283), Expect = 7e-26
Identities = 114/430 (26%), Positives = 170/430 (39%), Gaps = 62/430 (14%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYE-KDSKN--HTCVDVNECEIVDGVCG 172
Q +VNEC + P L G G C++ G + C C GY + +N H C D + C+
Sbjct: 1019 QHDVNECDSQPCLHG-GTCQDGCGSYRCTCPQGYTGPNCQNLVHWC-DSSPCK------N 1070
Query: 173 DGDCHNTEGSFTCHCRPGYKA--DDFSKICVDID---ECADNDALCR-GGRCVNTAGSFR 226
G C T + C C G+ D + ++ + D LC+ GG CV+ +
Sbjct: 1071 GGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH 1130
Query: 227 CECGHGMELAPDRLSCKD-IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHX 284
C C G + C+D +DECS + C NGA C + +G Y C C GY
Sbjct: 1131 CRCQAGYTGS----YCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 1184
Query: 285 XXXXXXXXXXXRCQH--SCVNTPGSYHCTC---REGWHLRADGRSCRD-IDECAGGARPC 338
CQ+ +C++ P +Y C+C +G H + C +D + +
Sbjct: 1185 DECLSHP-----CQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCF 1239
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAA-GAKPTC-------QDIDECADLISTI-IMMSVDE 389
G C + VG Y+CTC G V G C + C ++
Sbjct: 1240 NNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH 1299
Query: 390 LQKSVDPQIPELCG-----AGSC---HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
+ + I G G+C NT F+C+CP G+ +G C ++D G
Sbjct: 1300 TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF-----EGATC-ENDARTCG 1353
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGS--F 499
+ C CI+ P S C C + G CL N C+ + TC T S +
Sbjct: 1354 SLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGN-PCYNQGTCEPTSESPFY 1412
Query: 500 RCLCDTGYKG 509
RCLC + G
Sbjct: 1413 RCLCPAKFNG 1422
Score = 115 bits (276), Expect = 5e-25
Identities = 108/364 (29%), Positives = 145/364 (39%), Gaps = 71/364 (19%)
Query: 206 CADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSN-GAC--- 260
C+ C GG+C G+ C CG G + P C+D + C T C N G C
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCG-GAFVGP---RCQDPNPCLSTP--CKNAGTCHVV 77
Query: 261 -ENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC-VNTPGSYHCTCREGWHL 318
+ Y C C G++ + R +C + T Y C C GW
Sbjct: 78 DRRGVADYACSCALGFSGPLCLT--PLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGW-- 133
Query: 319 RADGRSCRDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTC-QDIDECA 376
G+SC+ D CA + PC GGQC SY C C PS G PTC QD++EC
Sbjct: 134 --SGKSCQQADPCA--SNPCANGGQCLPFEASYICHCP----PSFHG--PTCRQDVNECG 183
Query: 377 DLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGP-ACTD 434
Q P LC G+CHN +GS+ C C ++ + P
Sbjct: 184 --------------------QKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCS 223
Query: 435 DDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCAN 494
C+ G C P D + +C C G+ G E++D+C NN C C +
Sbjct: 224 PSPCQNGG-TCRPTGDV-----THECACLPGFTGQNCE-ENIDDCPGNN--CKNGGACVD 274
Query: 495 TDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCD 553
++ C C + G Y D+DEC P C+N G C NT GGY C C
Sbjct: 275 GVNTYNCRCPPEWTGQ----------YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCV 324
Query: 554 VGFT 557
G+T
Sbjct: 325 NGWT 328
>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
Length = 1246
Score = 191 bits (465), Expect = 7e-48
Identities = 111/331 (33%), Positives = 153/331 (46%), Gaps = 30/331 (9%)
Query: 181 GSFTCHC-RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDR 239
G + CH + GY + D+DEC ++ C+ RCVNT GS+ CEC G L D
Sbjct: 52 GCYPCHLGQAGYPVSAGDQR-PDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDS 109
Query: 240 LSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
+C I+ C++ +G C + + + ++C C G+ H C H
Sbjct: 110 RTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH 169
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C G C C G+ L ADG++C D+DECA G C G C NT GS+ C C G
Sbjct: 170 RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYE 228
Query: 360 PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCP 419
A G + C I+ M V+ + + C G H + G +C CP
Sbjct: 229 LGADGRQ--CYRIE----------MEIVNSCEANNGG-----CSHGCSHTSAGP-LCTCP 270
Query: 420 DGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVD 477
GY + +Q C D D+C C C C N PG ++C C G+R DG CEDVD
Sbjct: 271 RGYELDTDQR-TCIDVDDCADSPC-CQQV--CTNNPGGYECGCYAGYRLSADGCGCEDVD 326
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
EC ++ GGC C N GSF+C C+ GY+
Sbjct: 327 ECASSRGGCEHH--CTNLAGSFQCSCEAGYR 355
Score = 178 bits (433), Expect = 5e-44
Identities = 91/264 (34%), Positives = 127/264 (48%), Gaps = 12/264 (4%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC G C H RC N G + C+C PG+ + + TC+ +N C + +G C
Sbjct: 73 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 131
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
T C CRPG++ + + CV CA+ + C RC G RCEC G +LA
Sbjct: 132 LTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCM-HRCQVVRGLARCECHVGYQLAA 190
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-----AQSTVKSHXXXXXXXXX 292
D +C+D+DEC+ C++G C N G+++CVC GY + +
Sbjct: 191 DGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEA 249
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C H C +T CTC G+ L D R+C D+D+CA PC C N G Y C
Sbjct: 250 NNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS--PCCQQVCTNNPGGYEC 307
Query: 353 TCTDGLVPSAAGAKPTCQDIDECA 376
C G SA G C+D+DECA
Sbjct: 308 GCYAGYRLSADGC--GCEDVDECA 329
Score = 162 bits (393), Expect = 3e-39
Identities = 121/408 (29%), Positives = 160/408 (39%), Gaps = 46/408 (11%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+ +N CA G C H + + C C PG++ CV + C +G C C
Sbjct: 113 LAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHR-C 171
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
G C C GY+ K C D+DECA A C G C+NT GSF+C C G EL
Sbjct: 172 QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELG 230
Query: 237 PD-----RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
D R+ + ++ C +G CS+G G C C GY T
Sbjct: 231 ADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPL-CTCPRGYELDT-DQRTCIDVDDC 288
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
CQ C N PG Y C C G+ L ADG C D+DECA C C N GS+
Sbjct: 289 ADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGSFQ 347
Query: 352 CTCTDG--LVPSAAGAKPTCQ---DIDECADLISTIIMMSV--DELQK-------SVDPQ 397
C+C G L G P + D+D + + ++V DEL + D +
Sbjct: 348 CSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEE 407
Query: 398 IPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS 457
EL G H FVC D + +C L DC C L G
Sbjct: 408 EAELRGE---HTLTEKFVC-LDDSFG------------HDCSLTCDDCRNGGTC--LLGL 449
Query: 458 FQCRCRDGWRG--DGATC--EDVDECLTNNGGCHPRATCANTDGSFRC 501
C C +GW G TC + + + + C TC + G+ RC
Sbjct: 450 DGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC 497
Score = 148 bits (359), Expect = 5e-35
Identities = 96/276 (34%), Positives = 123/276 (44%), Gaps = 44/276 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
CQH CVNTPGSY C C+ G+ L D R+C I+ CA G C + T+ + C C
Sbjct: 84 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP 143
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G G C CA+ + + C G C
Sbjct: 144 GFQLQEDGRH--CVRRSPCANRNGSCMHR---------------------CQVVRGLARC 180
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATC- 473
+C GY + + G AC D DEC G C A C+N GSF+C C G+ DG C
Sbjct: 181 ECHVGYQLAAD-GKACEDVDECAAGLAQC--AHGCLNTQGSFKCVCHAGYELGADGRQCY 237
Query: 474 ----EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
E V+ C NNGGC C++T C C GY+ D RT C+D+D+C
Sbjct: 238 RIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDT-DQRT------CIDVDDC 288
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
A+ P C C+N PGGYEC C G+ +ADG C
Sbjct: 289 ADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGC 322
Score = 137 bits (331), Expect = 1e-31
Identities = 99/328 (30%), Positives = 137/328 (41%), Gaps = 43/328 (13%)
Query: 244 DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVN 303
D+DEC +G C + C N G+Y C C G+ T CQH CV
Sbjct: 73 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 131
Query: 304 TPGSYH-CTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSA 362
+ H C CR G+ L+ DGR C CA C +C+ G C C G +A
Sbjct: 132 LTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLAA 190
Query: 363 AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGY 422
G C+D+DECA ++ C G C NT GSF C C GY
Sbjct: 191 DGK--ACEDVDECAAGLAQ--------------------CAHG-CLNTQGSFKCVCHAGY 227
Query: 423 SVKPEQGPACTDDDECELGTCDCHPAA---DCINLPGSFQCRCRDGWR--GDGATCEDVD 477
+ + G C + + +C+ + C + C C G+ D TC DVD
Sbjct: 228 ELGAD-GRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVD 286
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
+C ++ C + C N G + C C GY+ G C C D+DECA+ CE
Sbjct: 287 DC-ADSPCC--QQVCTNNPGGYECGCYAGYRLSADG-----C--GCEDVDECASSRGGCE 336
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
+ HC+N G ++C C+ G+ D R C
Sbjct: 337 H-HCTNLAGSFQCSCEAGYRLHEDRRGC 363
Score = 89.8 bits (213), Expect = 2e-17
Identities = 76/268 (28%), Positives = 102/268 (38%), Gaps = 43/268 (16%)
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGA 365
G Y C + + + G D+DEC C +C NT GSY C C G
Sbjct: 52 GCYPCHLGQAGYPVSAGDQRPDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSR 110
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN-----TIGSFVCQCPD 420
TC I+ CA G G C + TI CQC
Sbjct: 111 --TCLAINSCA-------------------------LGNGGCQHHCVQLTITRHRCQCRP 143
Query: 421 GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDE 478
G+ ++ E G C C C + G +C C G++ DG CEDVDE
Sbjct: 144 GFQLQ-EDGRHCVRRSPCANRNGSCMHRCQVVR--GLARCECHVGYQLAADGKACEDVDE 200
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN 538
C C C NT GSF+C+C GY+ G + C ++ C + C +
Sbjct: 201 CAAGLAQC--AHGCLNTQGSFKCVCHAGYELGADGRQ--CYRIEMEIVNSCEANNGGCSH 256
Query: 539 GHCSNTPGGYECDCDVGFTRAADGRSCL 566
G CS+T G C C G+ D R+C+
Sbjct: 257 G-CSHTSAGPLCTCPRGYELDTDQRTCI 283
Score = 61.3 bits (142), Expect = 9e-09
Identities = 106/460 (23%), Positives = 143/460 (31%), Gaps = 57/460 (12%)
Query: 129 CGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVN---ECEIVDGVCGDGD-CHNTEGSFT 184
CG C + G C C PG + C + C+ + C C G+
Sbjct: 658 CGGAPCHGVTG--QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA-- 713
Query: 185 CHCRPGYKADDFSKICVDI---DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
C C PG+ +C C + G C G C C G + +
Sbjct: 714 CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATG--HCSCAPGWTGFSCQRA 771
Query: 242 CKDID---ECSITSGICS--NGACENQMGTYQCVCDEGYAQSTVKSH--XXXXXXXXXXX 294
C +CS CS +G+C+ G C+C+ GY +
Sbjct: 772 CDTGHWGPDCSHPCN-CSAGHGSCDAISGL--CLCEAGYVGPRCEQQCPQGHFGPGCEQL 828
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
+CQH S CTC GW G C C G G CR+ C C
Sbjct: 829 CQCQHGAACDHVSGACTCPAGWR----GTFCEHA--CPAGFF---GLDCRSA-----CNC 874
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
T G A C + V ++ G C G
Sbjct: 875 TAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDV----RAGCRHSGGCLNGGLCDPHTGR- 929
Query: 415 VCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC 473
C CP G++ Q P E C C PAA C ++ G+ CRC G+ G G C
Sbjct: 930 -CLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGA--CRCPPGFTGSG--C 984
Query: 474 EDVDECLTNNGGCHPRATCAN----TDGSFRCLCDTGYKGDGYGLRTVCCVY--SCVDID 527
E GC C N + C C TG+ G L + +C +
Sbjct: 985 EQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVC 1044
Query: 528 ECANDPTLCE--NGHCSNTPGGYECDCDVGFTRAADGRSC 565
C C+ G C PG C+ G + G C
Sbjct: 1045 GCGQG-AACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGC 1083
Score = 58.4 bits (135), Expect = 6e-08
Identities = 110/456 (24%), Positives = 148/456 (32%), Gaps = 66/456 (14%)
Query: 130 GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVN---ECEIVDGVCGDGDCHNTEGSFTCH 186
GHG C + G C C GY C + CE + C + G+ C
Sbjct: 790 GHGSCDAISG--LCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGA--CT 845
Query: 187 CRPGYKADDFSKICVDIDECADNDALCR---GGRCVNTAGSFRCECGHGMELAPDRLSCK 243
C G++ C D + C G C GS C G ++ +
Sbjct: 846 CPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPR 905
Query: 244 DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
D+ SG C NG C+ G +C+C G+ +S RC SC
Sbjct: 906 DVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRC--SCP 961
Query: 303 NTPGSYH----CTCREGWHLRADGRSCRDIDECAGGARPCG---GGQCRNTVGSYTCTCT 355
+H C C G+ + C G + CG GG C G+ C C
Sbjct: 962 PAAACHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCP 1019
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG---SCHNTIG 412
G + + TC Q P +CG G +C G
Sbjct: 1020 TGFLGTDCNL--TCP--------------------QGRFGPNCTHVCGCGQGAACDPVTG 1057
Query: 413 SFVCQCPDGYS-VKPEQG-PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
+ C CP G + V+ E+G P CE TC C C GS C C GW G
Sbjct: 1058 T--CLCPPGRAGVRCERGCPQNRFGVGCE-HTCSCRNGGLCHASNGS--CSCGLGWTGRH 1112
Query: 471 A--TCED--VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI 526
C CH +TC G+ C C G+ G R + +D
Sbjct: 1113 CELACPPGRYGAACHLECSCHNNSTCEPATGT--CRCGPGFYGQACEHRRSGATCN-LDC 1169
Query: 527 DECANDPTLCENGHCSNTPGGYECDCDVGFTRAADG 562
P+ C HC + GG +CD G DG
Sbjct: 1170 RRGQFGPS-C-TLHC-DCGGGADCDPVSGQCHCVDG 1202
Score = 51.6 bits (118), Expect = 7e-06
Identities = 109/428 (25%), Positives = 138/428 (32%), Gaps = 51/428 (11%)
Query: 152 DSKNHTC-VDVNECEIVDGVC--GDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECAD 208
DS H C + ++C G C G C EG C D F K C C +
Sbjct: 426 DSFGHDCSLTCDDCRN-GGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQN 484
Query: 209 NDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDE-CSITSGICSNGACENQMGTY 267
GG C + G+ RC G D + C + G C G
Sbjct: 485 ------GGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA- 537
Query: 268 QCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREG-WHLRADGRSCR 326
C+CD G CQ CV P + C R+G +A R R
Sbjct: 538 -CLCDPGLYGRFCHLTCPPWAFGPGCSEECQ--CVQ-PHTQSCDKRDGSCSCKAGFRGER 593
Query: 327 DIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAKPTCQDI-DECADLISTIIM 384
EC G G Q C VG C G A +D EC + T
Sbjct: 594 CQAECELGYFGPGCWQACTCPVG-VACDSVSGECGKRCPAGFQGEDCGQECP--VGTF-- 648
Query: 385 MSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCD 444
V+ CG CH G C+CP G + E A + LG +
Sbjct: 649 --------GVNCSSSCSCGGAPCHGVTGQ--CRCPPGRT--GEDCEADCPEGRWGLGCQE 696
Query: 445 ----CHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFR 500
C AA C P + C C G+ G + C+DV C R +CAN DG
Sbjct: 697 ICPACQHAARCD--PETGACLCLPGFVG--SRCQDVCPAGWYGPSCQTRCSCAN-DG--H 749
Query: 501 CLCDTGYKGDGYGLRTVCCVYSCVDIDECAND---PTLCENGHCSNTPGGYECDCDVGFT 557
C TG+ G C +C D D P C GH S C C+ G+
Sbjct: 750 CHPATGHCSCAPGWTGFSCQRAC-DTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYV 808
Query: 558 RAADGRSC 565
+ C
Sbjct: 809 GPRCEQQC 816
Score = 36.3 bits (80), Expect = 0.29
Identities = 88/367 (23%), Positives = 113/367 (30%), Gaps = 50/367 (13%)
Query: 129 CGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV--DVNE-CEIVDGVCGDGDCHNTEGSFTC 185
C G + + G +C C G C+ DV C G G C G C
Sbjct: 874 CTAGAACDAVNG-SCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTGR--C 930
Query: 186 HCRPGYKADDFSKICVDI---DECADNDALCRGGRCVNTAGSFRCE---CGHGMELA--P 237
C G+ D C+ + CA + C + G+ RC G G E P
Sbjct: 931 LCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQGCPP 990
Query: 238 DRLS--CKDIDECSITSGIC--SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
R C+ + C + G C + GAC G C+ Q +
Sbjct: 991 GRYGPGCEQLCGC-LNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQG 1049
Query: 294 XXRCQH---SCVNTPGSYHCTCREGWHLRADGRSCRDIDECA-GGARPCGGGQCRNTVGS 349
C +C+ PG C G G C C GG G C +G
Sbjct: 1050 AA-CDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGW 1108
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
C P GA C C + S E P G H
Sbjct: 1109 TGRHCELACPPGRYGA--ACHLECSCHN-------NSTCEPATGTCRCGPGFYGQACEHR 1159
Query: 410 TIGSFV-CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG 468
G+ C G + GP+CT CDC ADC P S QC C DG+
Sbjct: 1160 RSGATCNLDCRRG-----QFGPSCTLH-------CDCGGGADCD--PVSGQCHCVDGYM- 1204
Query: 469 DGATCED 475
G TC +
Sbjct: 1205 -GPTCRE 1210
>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
Length = 2444
Score = 190 bits (464), Expect = 9e-48
Identities = 149/463 (32%), Positives = 200/463 (43%), Gaps = 70/463 (15%)
Query: 120 NECAAFPGLCGHGRCRNL-LGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCH 177
N C P G G C L L + C C PG+ S C + C C +G C
Sbjct: 104 NACLTNPCRNG-GTCDLLTLTEYKCRCPPGWSGKS----CQQADPC--ASNPCANGGQCL 156
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELA 236
E S+ CHC P + + D++EC LCR GG C N GS+RC C
Sbjct: 157 PFEASYICHCPPSFHGPTCRQ---DVNECGQKPRLCRHGGTCHNEVGSYRCVC-RATHTG 212
Query: 237 PDRLSC-KDIDECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
P+ C + CS + C NG G T++C C G+ + +
Sbjct: 213 PN---CERPYVPCSPSP--CQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGN--- 264
Query: 294 XXRCQH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGS 349
C++ +CV+ +Y+C C W G+ C D+DEC C GG C NT G
Sbjct: 265 --NCKNGGACVDGVNTYNCPCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGG 318
Query: 350 YTCTCTDGLVPSAAG------AKPTCQDIDECADLISTIIMMS----VDELQKSVDPQIP 399
Y C C +G A C C D +++ L D I
Sbjct: 319 YNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS 378
Query: 400 ELCGAGS-CH-NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLP 455
C GS C N + G +C CP GY+ GPAC+ D DEC LG C A CIN
Sbjct: 379 NPCNEGSNCDTNPVNGKAICTCPSGYT-----GPACSQDVDECSLGANPCEHAGKCINTL 433
Query: 456 GSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
GSF+C+C G+ G CE DV+EC++N C ATC + G F+C+C GY+G
Sbjct: 434 GSFECQCLQGY--TGPRCEIDVNECVSN--PCQNDATCLDQIGEFQCMCMPGYEG----- 484
Query: 515 RTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
V+ V+ DECA+ P L NG C + ++C+C GFT
Sbjct: 485 -----VHCEVNTDECASSPCL-HNGRCLDKINEFQCECPTGFT 521
Score = 178 bits (433), Expect = 5e-44
Identities = 141/466 (30%), Positives = 203/466 (43%), Gaps = 77/466 (16%)
Query: 118 EVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGD 175
+V+EC+ C H G+C N LG F C C GY +DVNEC V C D
Sbjct: 412 DVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCE---IDVNEC--VSNPCQNDAT 466
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C + G F C C PGY+ V+ DECA + L GRC++ F+CEC G
Sbjct: 467 CLDQIGEFQCMCMPGYEGVHCE---VNTDECASSPCL-HNGRCLDKINEFQCECPTGFT- 521
Query: 236 APDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
L D+DEC+ T C NGA C + TY CVC EGY + +
Sbjct: 522 --GHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGYTGTHCE-----VDIDECDP 572
Query: 295 XRCQH-SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYT 351
C + SC + ++ C CR G+ G C +I+EC+ ++PC G C++ +Y
Sbjct: 573 DPCHYGSCKDGVATFTCLCRPGY----TGHHCETNINECS--SQPCRLRGTCQDPDNAYL 626
Query: 352 CTCTDGLVPSAAGAKPTCQ-DIDECAD--LISTIIMMSVDELQKSVDP---------QIP 399
C C G P C+ ++D+CA S + +D + + +P I
Sbjct: 627 CFCLKGTTG------PNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNSNID 680
Query: 400 ELCG-----AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCIN 453
E G G+C + I F C+CP+GY P C + +EC C D +N
Sbjct: 681 ECAGNPCHNGGTCEDGINGFTCRCPEGY-----HDPTCLSEVNECNSNPCVHGACRDSLN 735
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
++C C GW G + +EC +N C TC + C C G+ G
Sbjct: 736 ---GYKCDCDPGWSGTNCDINN-NECESNP--CVNGGTCKDMTSGIVCTCREGFSGPN-- 787
Query: 514 LRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRA 559
C +I+ECA++P L G C + GY+C+C + +T A
Sbjct: 788 -----CQ---TNINECASNPCL-NKGTCIDDVAGYKCNCLLPYTGA 824
Score = 169 bits (411), Expect = 2e-41
Identities = 136/453 (30%), Positives = 190/453 (41%), Gaps = 80/453 (17%)
Query: 116 QMEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC P LC H G C N +G + C C + + V + +G G
Sbjct: 176 RQDVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNG----G 231
Query: 175 DCHNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C T + + C C PG+ + + +ID+C N+ GG CV+ ++ C C
Sbjct: 232 TCRPTGDVTHECACLPGFTGQNCEE---NIDDCPGNNCK-NGGACVDGVNTYNCPCPPEW 287
Query: 234 ELAPDRLSCKDIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+ +D+DEC + C N G C N G Y CVC G+ +
Sbjct: 288 ---TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAA- 343
Query: 293 XXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQC-RNTV- 347
C H +C + S++C C G G C D C + PC G C N V
Sbjct: 344 ----CFHGATCHDRVASFYCECPHG----RTGLLCHLNDACI--SNPCNEGSNCDTNPVN 393
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
G CTC G A QD+DEC+ + + + AG C
Sbjct: 394 GKAICTCPSGYTGPACS-----QDVDECS--------LGANPCEH-----------AGKC 429
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
NT+GSF CQC GY+ GP C D +EC + C A C++ G FQC C G+
Sbjct: 430 INTLGSFECQCLQGYT-----GPRCEIDVNECV--SNPCQNDATCLDQIGEFQCMCMPGY 482
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+G CE + DEC ++ C C + F+C C TG+ G C Y D
Sbjct: 483 --EGVHCEVNTDECASS--PCLHNGRCLDKINEFQCECPTGFTGH-------LCQY---D 528
Query: 526 IDECANDPTLCENG-HCSNTPGGYECDCDVGFT 557
+DECA+ P C+NG C + P Y C C G+T
Sbjct: 529 VDECASTP--CKNGAKCLDGPNTYTCVCTEGYT 559
Score = 156 bits (378), Expect = 2e-37
Identities = 130/462 (28%), Positives = 197/462 (42%), Gaps = 70/462 (15%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
Q +V+ECA+ P C +G +C + +TC C GY + H VD++EC+ C G
Sbjct: 526 QYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGY---TGTHCEVDIDECD--PDPCHYG 578
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + +FTC CRPGY +I+EC+ RG C + ++ C C G
Sbjct: 579 SCKDGVATFTCLCRPGYTGHHCE---TNINECSSQPCRLRG-TCQDPDNAYLCFCLKGTT 634
Query: 235 LAPDRLSCK-DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
P+ C+ ++D+C+ S C +G C +++ Y+C C+ GY S S+
Sbjct: 635 -GPN---CEINLDDCA--SSPCDSGTCLDKIDGYECACEPGYTGSMCNSNIDECAGNPCH 688
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
+C + + C C EG+H D +++EC + PC G CR+++ Y C
Sbjct: 689 NG---GTCEDGINGFTCRCPEGYH---DPTCLSEVNEC--NSNPCVHGACRDSLNGYKCD 740
Query: 354 CTDGL------VPSAAGAKPTCQDIDECADLISTIIM-----MSVDELQKSVDPQIPELC 402
C G + + C + C D+ S I+ S Q +++ C
Sbjct: 741 CDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPC 800
Query: 403 -GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTC---DCHPAADCINLPG-- 456
G+C + + + C C + P G C E L C C +C
Sbjct: 801 LNKGTCIDDVAGYKCNC-----LLPYTGATC----EVVLAPCAPSPCRNGGECRQSEDYE 851
Query: 457 SFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
SF C C G TCE D++EC+ + C A+C NT G +RC C GY G
Sbjct: 852 SFSCVCPTA-GAKGQTCEVDINECVLS--PCRHGASCQNTHGXYRCHCQAGYSGRN---- 904
Query: 516 TVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
C DID+C +P C N G C++ CDC GF
Sbjct: 905 ---CE---TDIDDCRPNP--CHNGGSCTDGINTAFCDCLPGF 938
Score = 154 bits (374), Expect = 7e-37
Identities = 139/482 (28%), Positives = 201/482 (41%), Gaps = 84/482 (17%)
Query: 126 PGLCGHGRCRNLLGGFT--CDCFPGYEKDSKNHTCVDV--NECEIVDGVCGDGDCHNTEG 181
P C +G G T C C PG+ + D N C+ G C DG NT
Sbjct: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKN-GGACVDGV--NT-- 278
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRL 240
+ C C P + ++ D+DEC C+ GG C NT G + C C +G D
Sbjct: 279 -YNCPCPPEWTGQYCTE---DVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT-GED-- 331
Query: 241 SCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
++ID+C+ S C +GA C +++ ++ C C G + C
Sbjct: 332 CSENIDDCA--SAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDT 389
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDG 357
+ VN G CTC G+ G +C +D+DEC+ GA PC G+C NT+GS+ C C G
Sbjct: 390 NPVN--GKAICTCPSGY----TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQG 443
Query: 358 LVPSAAG------AKPTCQDIDECADLISTIIMMSVD-----ELQKSVDPQIPELC-GAG 405
CQ+ C D I M + + + D C G
Sbjct: 444 YTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECASSPCLHNG 503
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRD 464
C + I F C+CP G++ G C D DEC + C A C++ P ++ C C +
Sbjct: 504 RCLDKINEFQCECPTGFT-----GHLCQYDVDEC--ASTPCKNGAKCLDGPNTYTCVCTE 556
Query: 465 GWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG------------DG 511
G+ G CE D+DEC + CH +C + +F CLC GY G
Sbjct: 557 GYTG--THCEVDIDEC--DPDPCH-YGSCKDGVATFTCLCRPGYTGHHCETNINECSSQP 611
Query: 512 YGLRTVCC----VYSC------------VDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
LR C Y C +++D+CA+ P C++G C + GYEC C+ G
Sbjct: 612 CRLRGTCQDPDNAYLCFCLKGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPG 669
Query: 556 FT 557
+T
Sbjct: 670 YT 671
Score = 149 bits (360), Expect = 3e-35
Identities = 138/451 (30%), Positives = 187/451 (41%), Gaps = 86/451 (19%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
EVNEC + P C HG CR+ L G+ CDC PG+ S + ++ NECE V G G C
Sbjct: 716 EVNECNSNP--CVHGACRDSLNGYKCDCDPGW---SGTNCDINNNECESNPCVNG-GTCK 769
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
+ C CR G+ + +I+ECA N L + G C++ ++C C L P
Sbjct: 770 DMTSGIVCTCREGFSGPNCQ---TNINECASNPCLNK-GTCIDDVAGYKCNC-----LLP 820
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQ---CVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ ++ C NG Q Y+ CVC A K
Sbjct: 821 YTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTAGA----KGQTCEVDINECVL 876
Query: 295 XRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C+H SC NT G Y C C+ G+ GR+C DID+C PC GG C + + +
Sbjct: 877 SPCRHGASCQNTHGXYRCHCQAGY----SGRNCETDIDDCR--PNPCHNGGSCTDGINTA 930
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHN 409
C C G + +DI+ECA DP C G +C +
Sbjct: 931 FCDCLPGFRGTFCE-----EDINECAS-----------------DP-----CRNGANCTD 963
Query: 410 TIGSFVCQCPDGYS-VKPEQG-PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR 467
+ S+ C CP G+S + E P CT+ GTC D IN SF C C G+
Sbjct: 964 CVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTC-----VDGIN---SFTCLCPPGF- 1014
Query: 468 GDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI 526
G+ C+ V+EC ++ C TC + G RC C GY G V+ C D
Sbjct: 1015 -TGSYCQHVVNEC--DSRPCLLGGTCQDGRGLHRCTCPQGYTGP----NCQNLVHWC-DS 1066
Query: 527 DECANDPTLCENGHCSNTPGGYECDCDVGFT 557
C N G C T Y C+C G+T
Sbjct: 1067 SPCKN------GGKCWQTHTQYRCECPSGWT 1091
Score = 145 bits (352), Expect = 3e-34
Identities = 129/465 (27%), Positives = 190/465 (40%), Gaps = 67/465 (14%)
Query: 122 CAAFPGLCGHGRCRNL--LGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG-DCH 177
CA P G G CR F+C C P +K TC VD+NEC + C G C
Sbjct: 833 CAPSPCRNG-GECRQSEDYESFSCVC-P--TAGAKGQTCEVDINECVL--SPCRHGASCQ 886
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT G + CHC+ GY + DID+C N GG C + + C+C G
Sbjct: 887 NTHGXYRCHCQAGYSGRNCE---TDIDDCRPNPCH-NGGSCTDGINTAFCDCLPGFR--- 939
Query: 238 DRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+DI+EC+ S C NGA C + + +Y C C G++ +++
Sbjct: 940 GTFCEEDINECA--SDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG 997
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVGSYTCTC 354
+CV+ S+ C C G+ G C+ + +EC +RPC GG C++ G + CTC
Sbjct: 998 ---TCVDGINSFTCLCPPGF----TGSYCQHVVNEC--DSRPCLLGGTCQDGRGLHRCTC 1048
Query: 355 TDGLV--------------PSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKS 393
G P G K C+ L + +S + +
Sbjct: 1049 PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQR 1108
Query: 394 VDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADC 451
+ LC G C + + C+C GY+ G C D DEC C A C
Sbjct: 1109 QGVDVARLCQHGGLCVDAGNTHHCRCQAGYT-----GSYCEDLVDECS--PSPCQNGATC 1161
Query: 452 INLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG 511
+ G + C+C G+ G + E++DECL++ C TC + +++C C G +G
Sbjct: 1162 TDYLGGYSCKCVAGYHGVNCS-EEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQGVH 1218
Query: 512 YGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
+ C +D + P NG C + GGY C C GF
Sbjct: 1219 CEINVDDCN---PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGF 1260
Score = 142 bits (343), Expect = 4e-33
Identities = 117/428 (27%), Positives = 172/428 (40%), Gaps = 66/428 (15%)
Query: 118 EVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++NECA+ P C +G C + + +TC C G+ + D E +G G C
Sbjct: 946 DINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG----GTC 999
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
+ SFTC C PG+ + ++EC L GG C + G RC C G
Sbjct: 1000 VDGINSFTCLCPPGFTGSYCQHV---VNECDSRPCLL-GGTCQDGRGLHRCTCPQGYT-G 1054
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ-----STVKSHXXXXXXXX 291
P+ C+++ +S + G C Y+C C G+ +V
Sbjct: 1055 PN---CQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGV 1111
Query: 292 XXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPC-GGGQCRNTV 347
CQH CV+ ++HC C+ G+ G C D +DEC+ PC G C + +
Sbjct: 1112 DVARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDLVDECSPS--PCQNGATCTDYL 1165
Query: 348 GSYTCTCTDGLVPSAAGAK------PTCQDIDECADLISTI------------IMMSVDE 389
G Y+C C G + CQ+ C DL +T ++VD+
Sbjct: 1166 GGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDD 1225
Query: 390 LQKSVDP--QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCH 446
VDP + P+ G+C + +G + C CP G+ G C D +EC CD
Sbjct: 1226 CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV-----GERCEGDVNECLSNPCDAR 1280
Query: 447 PAADCINLPGSFQCRCRDGWRGDGATCEDV-DEC----LTNNGGCHPRATCANTDGSFRC 501
+C+ F C CR G G CE V + C N G C A +NT F C
Sbjct: 1281 GTQNCVQRVNDFHCECRAG--HTGRRCESVINGCKGKPCKNGGTC---AVASNTARGFIC 1335
Query: 502 LCDTGYKG 509
C G++G
Sbjct: 1336 KCPAGFEG 1343
Score = 128 bits (309), Expect = 5e-29
Identities = 123/484 (25%), Positives = 198/484 (40%), Gaps = 80/484 (16%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
++++NEC P C HG C+N G + C C GY S + D+++C C +G
Sbjct: 868 EVDINECVLSP--CRHGASCQNTHGXYRCHCQAGY---SGRNCETDIDDCR--PNPCHNG 920
Query: 175 -DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PG++ + DI+ECA +D G C + S+ C C G
Sbjct: 921 GSCTDGINTAFCDCLPGFRGTFCEE---DINECA-SDPCRNGANCTDCVDSYTCTCPAGF 976
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
+ D E S +G G C + + ++ C+C G+ S + H
Sbjct: 977 SGIHCENNTPDCTESSCFNG----GTCVDGINSFTCLCPPGFTGSYCQ-HVVNECDSRPC 1031
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQCRNTVGSYTC 352
+C + G + CTC +G+ G +C+++ + PC GG+C T Y C
Sbjct: 1032 LLG--GTCQDGRGLHRCTCPQGY----TGPNCQNLVHWCDSS-PCKNGGKCWQTHTQYRC 1084
Query: 353 TCTDGL------VPSAA----------GAKPTCQDIDECADLISTIIMM-----SVDELQ 391
C G VPS + CQ C D +T + +
Sbjct: 1085 ECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE 1144
Query: 392 KSVDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAA 449
VD P C G+ C + +G + C+C GY G C+++ DEC + C
Sbjct: 1145 DLVDECSPSPCQNGATCTDYLGGYSCKCVAGY-----HGVNCSEEIDECL--SHPCQNGG 1197
Query: 450 DCINLPGSFQCRCRDGWRGDGATCE-DVDEC------LTNNGGCHPRATCANTDGSFRCL 502
C++LP +++C C G +G CE +VD+C ++ + C TC + G + C
Sbjct: 1198 TCLDLPNTYKCSCPRGTQG--VHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCT 1255
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGFTRAAD 561
C G+ G+ C D++EC ++P +C + C+C G T
Sbjct: 1256 CPPGFVGER-------CE---GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT---- 1301
Query: 562 GRSC 565
GR C
Sbjct: 1302 GRRC 1305
Score = 115 bits (277), Expect = 4e-25
Identities = 108/364 (29%), Positives = 145/364 (39%), Gaps = 71/364 (19%)
Query: 206 CADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSN-GAC--- 260
C+ C GG+C G+ C CG G + P C+D + C T C N G C
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCG-GAFVGP---RCQDPNPCLSTP--CKNAGTCHVV 77
Query: 261 -ENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC-VNTPGSYHCTCREGWHL 318
+ Y C C G++ + R +C + T Y C C GW
Sbjct: 78 DRRGVADYACSCALGFSGPLCLT--PLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGW-- 133
Query: 319 RADGRSCRDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTC-QDIDECA 376
G+SC+ D CA + PC GGQC SY C C PS G PTC QD++EC
Sbjct: 134 --SGKSCQQADPCA--SNPCANGGQCLPFEASYICHCP----PSFHG--PTCRQDVNECG 183
Query: 377 DLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGP-ACTD 434
Q P LC G+CHN +GS+ C C ++ + P
Sbjct: 184 --------------------QKPRLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCS 223
Query: 435 DDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCAN 494
C+ G C P D + +C C G+ G E++D+C NN C C +
Sbjct: 224 PSPCQNGG-TCRPTGDV-----THECACLPGFTGQNCE-ENIDDCPGNN--CKNGGACVD 274
Query: 495 TDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCD 553
++ C C + G Y D+DEC P C+N G C NT GGY C C
Sbjct: 275 GVNTYNCPCPPEWTGQ----------YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCV 324
Query: 554 VGFT 557
G+T
Sbjct: 325 NGWT 328
Score = 113 bits (272), Expect = 2e-24
Identities = 114/430 (26%), Positives = 168/430 (39%), Gaps = 62/430 (14%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYE-KDSKN--HTCVDVNECEIVDGVCG 172
Q VNEC + P L G G C++ G C C GY + +N H C D + C+
Sbjct: 1020 QHVVNECDSRPCLLG-GTCQDGRGLHRCTCPQGYTGPNCQNLVHWC-DSSPCK------N 1071
Query: 173 DGDCHNTEGSFTCHCRPGYKA--DDFSKICVDID---ECADNDALCR-GGRCVNTAGSFR 226
G C T + C C G+ D + ++ + D LC+ GG CV+ +
Sbjct: 1072 GGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH 1131
Query: 227 CECGHGMELAPDRLSCKD-IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHX 284
C C G + C+D +DECS + C NGA C + +G Y C C GY
Sbjct: 1132 CRCQAGYTGS----YCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 1185
Query: 285 XXXXXXXXXXXRCQH--SCVNTPGSYHCTC---REGWHLRADGRSCRD-IDECAGGARPC 338
CQ+ +C++ P +Y C+C +G H + C +D + +
Sbjct: 1186 DECLSHP-----CQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCF 1240
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAA-GAKPTC-------QDIDECADLISTI-IMMSVDE 389
G C + VG Y+CTC G V G C + C ++
Sbjct: 1241 NNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH 1300
Query: 390 LQKSVDPQIPELCG-----AGSC---HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
+ + I G G+C NT F+C+CP G+ +G C ++D G
Sbjct: 1301 TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF-----EGATC-ENDARTCG 1354
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGS--F 499
+ C CI+ P S C C + G CL N C+ + TC T S +
Sbjct: 1355 SLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGN-PCYNQGTCEPTSESPFY 1413
Query: 500 RCLCDTGYKG 509
RCLC + G
Sbjct: 1414 RCLCPAKFNG 1423
>AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens
cDNA FLJ14438 fis, clone HEMBB1000317, weakly similar to
FIBULIN-1, ISOFORM D PRECURSOR. ).
Length = 741
Score = 190 bits (464), Expect = 9e-48
Identities = 126/371 (33%), Positives = 172/371 (46%), Gaps = 48/371 (12%)
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
++G + C G+ D C D DECA + C N G++ C C G+ +A D
Sbjct: 307 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAAD 364
Query: 239 RLSCKDIDECSITSGICSNGA-CENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXX 295
+C+DIDEC++ C G C+N +G+Y+CV C G+ + T
Sbjct: 365 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSCQDINECQESS 423
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG-ARPCGGGQCRNTVGSYTC-- 352
C C N GS+HC C G+ L+ GR C D++EC RP C+NT G Y C
Sbjct: 424 PCHQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRP--DQHCKNTRGGYKCID 479
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C +G+ + G TC DIDEC D + + + QI C NT G
Sbjct: 480 LCPNGMTKAENG---TCIDIDECKD--------GTHQCRYN---QI--------CENTRG 517
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDG 470
S+ C CP GY G C D DECE T C +C N GS+QC C G++ +G
Sbjct: 518 SYRCVCPRGYR-SQGVGRPCMDIDECE-NTDACQ--HECKNTFGSYQCICPPGYQLTHNG 573
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLRTVCCVYSCVDID 527
TC+D+DECL N C P C N GS++C+ C Y+ D + C+ +C D
Sbjct: 574 KTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPV---SGFCLKNCPPND 630
Query: 528 -ECANDPTLCE 537
ECA P E
Sbjct: 631 LECALSPYALE 641
Score = 180 bits (438), Expect = 1e-44
Identities = 106/275 (38%), Positives = 138/275 (50%), Gaps = 44/275 (16%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT-- 353
C HSC N G+Y+C+C +G + ADGR+C+DIDECA G C GQ C NT+GSY C
Sbjct: 340 CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVR 399
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G ++ G +CQDI+EC Q+S P C C N IGS
Sbjct: 400 CGSGFRRTSDGL--SCQDINEC---------------QES-SP-----CHQ-RCFNAIGS 435
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC--RCRDGW-RGDG 470
F C C GY +K G C D +EC C P C N G ++C C +G + +
Sbjct: 436 FHCGCEPGYQLK---GRKCMDVNECRQNVC--RPDQHCKNTRGGYKCIDLCPNGMTKAEN 490
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECA 530
TC D+DEC C C NT GS+RC+C GY+ G G C+DIDEC
Sbjct: 491 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG-------RPCMDIDECE 543
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
N C++ C NT G Y+C C G+ +G++C
Sbjct: 544 NTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTC 576
Score = 175 bits (426), Expect = 3e-43
Identities = 120/351 (34%), Positives = 148/351 (42%), Gaps = 41/351 (11%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
C G+ DS C D +EC C CHN G++ C C G + C DID
Sbjct: 315 CPSGFTLDSVGPFCADEDECA-AGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 372
Query: 205 ECADNDALCRGGR-CVNTAGSFRC--ECGHGMELAPDRLSCKDIDECSITSGICSNGACE 261
ECA C G+ C NT GS+RC CG G D LSC+DI+EC S C + C
Sbjct: 373 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPC-HQRCF 430
Query: 262 NQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHC--TCREGWHLR 319
N +G++ C C+ GY K R C NT G Y C C G +
Sbjct: 431 NAIGSFHCGCEPGYQLKGRKC--MDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGM-TK 487
Query: 320 ADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
A+ +C DIDEC G C Q C NT GSY C C G G +P C DIDEC
Sbjct: 488 AENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG-RP-CMDIDECE-- 543
Query: 379 ISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC 438
+ D Q C NT GS+ C CP GY + G C D DEC
Sbjct: 544 -------NTDACQH-------------ECKNTFGSYQCICPPGYQL-THNGKTCQDIDEC 582
Query: 439 ELGTCDCHPAADCINLPGSFQC---RCRDGWRGDGATCEDVDECLTNNGGC 486
C P C N+ GS+QC C ++ D + + C N+ C
Sbjct: 583 LEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLEC 633
Score = 160 bits (388), Expect = 1e-38
Identities = 92/246 (37%), Positives = 124/246 (50%), Gaps = 16/246 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+++ECA C G+ C N +G + C C G+ + S +C D+NEC+ C
Sbjct: 370 DIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR 428
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCE--CGH 231
C N GSF C C PGY+ + C+D++EC N +CR + C NT G ++C C +
Sbjct: 429 -CFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPN 483
Query: 232 GMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
GM A + +C DIDEC + C N CEN G+Y+CVC GY V
Sbjct: 484 GMTKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGV-GRPCMDIDE 541
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGS 349
CQH C NT GSY C C G+ L +G++C+DIDEC CG + C N GS
Sbjct: 542 CENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGS 601
Query: 350 YTCTCT 355
Y C T
Sbjct: 602 YQCIDT 607
Score = 155 bits (375), Expect = 5e-37
Identities = 93/266 (34%), Positives = 127/266 (47%), Gaps = 21/266 (7%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHN 178
+ECAA C H C N +G + C C G + TC D++EC + C G DC N
Sbjct: 332 DECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDN 389
Query: 179 TEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
T GS+ C C G++ C DI+EC ++ C RC N GSF C C G +L
Sbjct: 390 TIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CH-QRCFNAIGSFHCGCEPGYQLK 447
Query: 237 PDRLSCKDIDECSITSGIC-SNGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXX 293
+ C D++EC +C + C+N G Y+C+ C G ++
Sbjct: 448 GRK--CMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE-NGTCIDIDECKDG 502
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C+++ C NT GSY C C G+ + GR C DIDEC C +C+NT GSY
Sbjct: 503 THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECE-NTDAC-QHECKNTFGSYQ 560
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECAD 377
C C G + G TCQDIDEC +
Sbjct: 561 CICPPGYQLTHNG--KTCQDIDECLE 584
Score = 144 bits (348), Expect = 1e-33
Identities = 97/261 (37%), Positives = 122/261 (46%), Gaps = 44/261 (16%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQD 371
C G+ L + G C D DECA G PC C N +G+Y C+C GL +A G TCQD
Sbjct: 315 CPSGFTLDSVGPFCADEDECAAG-NPCSHS-CHNAMGTYYCSCPKGLTIAADGR--TCQD 370
Query: 372 IDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVC--QCPDGYSVKPEQ 428
IDECA L + C AG C NTIGS+ C +C G+ +
Sbjct: 371 IDECA-------------LGRHT-------CHAGQDCDNTIGSYRCVVRCGSGFR-RTSD 409
Query: 429 GPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHP 488
G +C D +EC+ + CH C N GSF C C G++ G C DV+EC N C P
Sbjct: 410 GLSCQDINECQESS-PCHQR--CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNV--CRP 464
Query: 489 RATCANTDGSFRC--LCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTP 545
C NT G ++C LC G G +C+DIDEC + C N C NT
Sbjct: 465 DQHCKNTRGGYKCIDLCPNGMTKAENG--------TCIDIDECKDGTHQCRYNQICENTR 516
Query: 546 GGYECDCDVGFTRAADGRSCL 566
G Y C C G+ GR C+
Sbjct: 517 GSYRCVCPRGYRSQGVGRPCM 537
>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
Length = 2556
Score = 190 bits (464), Expect = 9e-48
Identities = 149/463 (32%), Positives = 200/463 (43%), Gaps = 70/463 (15%)
Query: 120 NECAAFPGLCGHGRCRNL-LGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCH 177
N C P G G C L L + C C PG+ S C + C C +G C
Sbjct: 104 NACLTNPCRNG-GTCDLLTLTEYKCRCPPGWSGKS----CQQADPC--ASNPCANGGQCL 156
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELA 236
E S+ CHC P + + D++EC LCR GG C N GS+RC C
Sbjct: 157 PFEASYICHCPPSFHGPTCRQ---DVNECGQKPRLCRHGGTCHNEVGSYRCVC-RATHTG 212
Query: 237 PDRLSC-KDIDECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
P+ C + CS + C NG G T++C C G+ + +
Sbjct: 213 PN---CERPYVPCSPSP--CQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGN--- 264
Query: 294 XXRCQH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGS 349
C++ +CV+ +Y+C C W G+ C D+DEC C GG C NT G
Sbjct: 265 --NCKNGGACVDGVNTYNCPCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGG 318
Query: 350 YTCTCTDGLVPSAAG------AKPTCQDIDECADLISTIIMMS----VDELQKSVDPQIP 399
Y C C +G A C C D +++ L D I
Sbjct: 319 YNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS 378
Query: 400 ELCGAGS-CH-NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLP 455
C GS C N + G +C CP GY+ GPAC+ D DEC LG C A CIN
Sbjct: 379 NPCNEGSNCDTNPVNGKAICTCPSGYT-----GPACSQDVDECSLGANPCEHAGKCINTL 433
Query: 456 GSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
GSF+C+C G+ G CE DV+EC++N C ATC + G F+C+C GY+G
Sbjct: 434 GSFECQCLQGY--TGPRCEIDVNECVSN--PCQNDATCLDQIGEFQCMCMPGYEG----- 484
Query: 515 RTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
V+ V+ DECA+ P L NG C + ++C+C GFT
Sbjct: 485 -----VHCEVNTDECASSPCL-HNGRCLDKINEFQCECPTGFT 521
Score = 178 bits (433), Expect = 5e-44
Identities = 141/466 (30%), Positives = 203/466 (43%), Gaps = 77/466 (16%)
Query: 118 EVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGD 175
+V+EC+ C H G+C N LG F C C GY +DVNEC V C D
Sbjct: 412 DVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCE---IDVNEC--VSNPCQNDAT 466
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C + G F C C PGY+ V+ DECA + L GRC++ F+CEC G
Sbjct: 467 CLDQIGEFQCMCMPGYEGVHCE---VNTDECASSPCL-HNGRCLDKINEFQCECPTGFT- 521
Query: 236 APDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
L D+DEC+ T C NGA C + TY CVC EGY + +
Sbjct: 522 --GHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGYTGTHCE-----VDIDECDP 572
Query: 295 XRCQH-SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYT 351
C + SC + ++ C CR G+ G C +I+EC+ ++PC G C++ +Y
Sbjct: 573 DPCHYGSCKDGVATFTCLCRPGY----TGHHCETNINECS--SQPCRLRGTCQDPDNAYL 626
Query: 352 CTCTDGLVPSAAGAKPTCQ-DIDECAD--LISTIIMMSVDELQKSVDP---------QIP 399
C C G P C+ ++D+CA S + +D + + +P I
Sbjct: 627 CFCLKGTTG------PNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNSNID 680
Query: 400 ELCG-----AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCIN 453
E G G+C + I F C+CP+GY P C + +EC C D +N
Sbjct: 681 ECAGNPCHNGGTCEDGINGFTCRCPEGY-----HDPTCLSEVNECNSNPCVHGACRDSLN 735
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
++C C GW G + +EC +N C TC + C C G+ G
Sbjct: 736 ---GYKCDCDPGWSGTNCDINN-NECESNP--CVNGGTCKDMTSGIVCTCREGFSGPN-- 787
Query: 514 LRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRA 559
C +I+ECA++P L G C + GY+C+C + +T A
Sbjct: 788 -----CQ---TNINECASNPCL-NKGTCIDDVAGYKCNCLLPYTGA 824
Score = 169 bits (411), Expect = 2e-41
Identities = 136/453 (30%), Positives = 190/453 (41%), Gaps = 80/453 (17%)
Query: 116 QMEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC P LC H G C N +G + C C + + V + +G G
Sbjct: 176 RQDVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNG----G 231
Query: 175 DCHNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C T + + C C PG+ + + +ID+C N+ GG CV+ ++ C C
Sbjct: 232 TCRPTGDVTHECACLPGFTGQNCEE---NIDDCPGNNCK-NGGACVDGVNTYNCPCPPEW 287
Query: 234 ELAPDRLSCKDIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+ +D+DEC + C N G C N G Y CVC G+ +
Sbjct: 288 ---TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAA- 343
Query: 293 XXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQC-RNTV- 347
C H +C + S++C C G G C D C + PC G C N V
Sbjct: 344 ----CFHGATCHDRVASFYCECPHG----RTGLLCHLNDACI--SNPCNEGSNCDTNPVN 393
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
G CTC G A QD+DEC+ + + + AG C
Sbjct: 394 GKAICTCPSGYTGPACS-----QDVDECS--------LGANPCEH-----------AGKC 429
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
NT+GSF CQC GY+ GP C D +EC + C A C++ G FQC C G+
Sbjct: 430 INTLGSFECQCLQGYT-----GPRCEIDVNECV--SNPCQNDATCLDQIGEFQCMCMPGY 482
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+G CE + DEC ++ C C + F+C C TG+ G C Y D
Sbjct: 483 --EGVHCEVNTDECASS--PCLHNGRCLDKINEFQCECPTGFTGH-------LCQY---D 528
Query: 526 IDECANDPTLCENG-HCSNTPGGYECDCDVGFT 557
+DECA+ P C+NG C + P Y C C G+T
Sbjct: 529 VDECASTP--CKNGAKCLDGPNTYTCVCTEGYT 559
Score = 156 bits (378), Expect = 2e-37
Identities = 130/462 (28%), Positives = 197/462 (42%), Gaps = 70/462 (15%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
Q +V+ECA+ P C +G +C + +TC C GY + H VD++EC+ C G
Sbjct: 526 QYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGY---TGTHCEVDIDECD--PDPCHYG 578
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + +FTC CRPGY +I+EC+ RG C + ++ C C G
Sbjct: 579 SCKDGVATFTCLCRPGYTGHHCE---TNINECSSQPCRLRG-TCQDPDNAYLCFCLKGTT 634
Query: 235 LAPDRLSCK-DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
P+ C+ ++D+C+ S C +G C +++ Y+C C+ GY S S+
Sbjct: 635 -GPN---CEINLDDCA--SSPCDSGTCLDKIDGYECACEPGYTGSMCNSNIDECAGNPCH 688
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
+C + + C C EG+H D +++EC + PC G CR+++ Y C
Sbjct: 689 NG---GTCEDGINGFTCRCPEGYH---DPTCLSEVNEC--NSNPCVHGACRDSLNGYKCD 740
Query: 354 CTDGL------VPSAAGAKPTCQDIDECADLISTIIM-----MSVDELQKSVDPQIPELC 402
C G + + C + C D+ S I+ S Q +++ C
Sbjct: 741 CDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPC 800
Query: 403 -GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTC---DCHPAADCINLPG-- 456
G+C + + + C C + P G C E L C C +C
Sbjct: 801 LNKGTCIDDVAGYKCNC-----LLPYTGATC----EVVLAPCAPSPCRNGGECRQSEDYE 851
Query: 457 SFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
SF C C G TCE D++EC+ + C A+C NT G +RC C GY G
Sbjct: 852 SFSCVCPTA-GAKGQTCEVDINECVLS--PCRHGASCQNTHGXYRCHCQAGYSGRN---- 904
Query: 516 TVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
C DID+C +P C N G C++ CDC GF
Sbjct: 905 ---CE---TDIDDCRPNP--CHNGGSCTDGINTAFCDCLPGF 938
Score = 154 bits (374), Expect = 7e-37
Identities = 139/482 (28%), Positives = 201/482 (41%), Gaps = 84/482 (17%)
Query: 126 PGLCGHGRCRNLLGGFT--CDCFPGYEKDSKNHTCVDV--NECEIVDGVCGDGDCHNTEG 181
P C +G G T C C PG+ + D N C+ G C DG NT
Sbjct: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKN-GGACVDGV--NT-- 278
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRL 240
+ C C P + ++ D+DEC C+ GG C NT G + C C +G D
Sbjct: 279 -YNCPCPPEWTGQYCTE---DVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT-GED-- 331
Query: 241 SCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
++ID+C+ S C +GA C +++ ++ C C G + C
Sbjct: 332 CSENIDDCA--SAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDT 389
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDG 357
+ VN G CTC G+ G +C +D+DEC+ GA PC G+C NT+GS+ C C G
Sbjct: 390 NPVN--GKAICTCPSGY----TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQG 443
Query: 358 LVPSAAG------AKPTCQDIDECADLISTIIMMSVD-----ELQKSVDPQIPELC-GAG 405
CQ+ C D I M + + + D C G
Sbjct: 444 YTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECASSPCLHNG 503
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRD 464
C + I F C+CP G++ G C D DEC + C A C++ P ++ C C +
Sbjct: 504 RCLDKINEFQCECPTGFT-----GHLCQYDVDEC--ASTPCKNGAKCLDGPNTYTCVCTE 556
Query: 465 GWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG------------DG 511
G+ G CE D+DEC + CH +C + +F CLC GY G
Sbjct: 557 GYTG--THCEVDIDEC--DPDPCH-YGSCKDGVATFTCLCRPGYTGHHCETNINECSSQP 611
Query: 512 YGLRTVCC----VYSC------------VDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
LR C Y C +++D+CA+ P C++G C + GYEC C+ G
Sbjct: 612 CRLRGTCQDPDNAYLCFCLKGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPG 669
Query: 556 FT 557
+T
Sbjct: 670 YT 671
Score = 149 bits (360), Expect = 3e-35
Identities = 138/451 (30%), Positives = 187/451 (41%), Gaps = 86/451 (19%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
EVNEC + P C HG CR+ L G+ CDC PG+ S + ++ NECE V G G C
Sbjct: 716 EVNECNSNP--CVHGACRDSLNGYKCDCDPGW---SGTNCDINNNECESNPCVNG-GTCK 769
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
+ C CR G+ + +I+ECA N L + G C++ ++C C L P
Sbjct: 770 DMTSGIVCTCREGFSGPNCQ---TNINECASNPCLNK-GTCIDDVAGYKCNC-----LLP 820
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQ---CVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ ++ C NG Q Y+ CVC A K
Sbjct: 821 YTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTAGA----KGQTCEVDINECVL 876
Query: 295 XRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C+H SC NT G Y C C+ G+ GR+C DID+C PC GG C + + +
Sbjct: 877 SPCRHGASCQNTHGXYRCHCQAGY----SGRNCETDIDDCR--PNPCHNGGSCTDGINTA 930
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHN 409
C C G + +DI+ECA DP C G +C +
Sbjct: 931 FCDCLPGFRGTFCE-----EDINECAS-----------------DP-----CRNGANCTD 963
Query: 410 TIGSFVCQCPDGYS-VKPEQG-PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR 467
+ S+ C CP G+S + E P CT+ GTC D IN SF C C G+
Sbjct: 964 CVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTC-----VDGIN---SFTCLCPPGF- 1014
Query: 468 GDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI 526
G+ C+ V+EC ++ C TC + G RC C GY G V+ C D
Sbjct: 1015 -TGSYCQHVVNEC--DSRPCLLGGTCQDGRGLHRCTCPQGYTGP----NCQNLVHWC-DS 1066
Query: 527 DECANDPTLCENGHCSNTPGGYECDCDVGFT 557
C N G C T Y C+C G+T
Sbjct: 1067 SPCKN------GGKCWQTHTQYRCECPSGWT 1091
Score = 145 bits (352), Expect = 3e-34
Identities = 129/465 (27%), Positives = 190/465 (40%), Gaps = 67/465 (14%)
Query: 122 CAAFPGLCGHGRCRNL--LGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG-DCH 177
CA P G G CR F+C C P +K TC VD+NEC + C G C
Sbjct: 833 CAPSPCRNG-GECRQSEDYESFSCVC-P--TAGAKGQTCEVDINECVL--SPCRHGASCQ 886
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT G + CHC+ GY + DID+C N GG C + + C+C G
Sbjct: 887 NTHGXYRCHCQAGYSGRNCE---TDIDDCRPNPCH-NGGSCTDGINTAFCDCLPGFR--- 939
Query: 238 DRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+DI+EC+ S C NGA C + + +Y C C G++ +++
Sbjct: 940 GTFCEEDINECA--SDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG 997
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVGSYTCTC 354
+CV+ S+ C C G+ G C+ + +EC +RPC GG C++ G + CTC
Sbjct: 998 ---TCVDGINSFTCLCPPGF----TGSYCQHVVNEC--DSRPCLLGGTCQDGRGLHRCTC 1048
Query: 355 TDGLV--------------PSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKS 393
G P G K C+ L + +S + +
Sbjct: 1049 PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQR 1108
Query: 394 VDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADC 451
+ LC G C + + C+C GY+ G C D DEC C A C
Sbjct: 1109 QGVDVARLCQHGGLCVDAGNTHHCRCQAGYT-----GSYCEDLVDECS--PSPCQNGATC 1161
Query: 452 INLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG 511
+ G + C+C G+ G + E++DECL++ C TC + +++C C G +G
Sbjct: 1162 TDYLGGYSCKCVAGYHGVNCS-EEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQGVH 1218
Query: 512 YGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
+ C +D + P NG C + GGY C C GF
Sbjct: 1219 CEINVDDCN---PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGF 1260
Score = 142 bits (343), Expect = 4e-33
Identities = 117/428 (27%), Positives = 172/428 (40%), Gaps = 66/428 (15%)
Query: 118 EVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++NECA+ P C +G C + + +TC C G+ + D E +G G C
Sbjct: 946 DINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG----GTC 999
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
+ SFTC C PG+ + ++EC L GG C + G RC C G
Sbjct: 1000 VDGINSFTCLCPPGFTGSYCQHV---VNECDSRPCLL-GGTCQDGRGLHRCTCPQGYT-G 1054
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ-----STVKSHXXXXXXXX 291
P+ C+++ +S + G C Y+C C G+ +V
Sbjct: 1055 PN---CQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGV 1111
Query: 292 XXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPC-GGGQCRNTV 347
CQH CV+ ++HC C+ G+ G C D +DEC+ PC G C + +
Sbjct: 1112 DVARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDLVDECSPS--PCQNGATCTDYL 1165
Query: 348 GSYTCTCTDGLVPSAAGAK------PTCQDIDECADLISTI------------IMMSVDE 389
G Y+C C G + CQ+ C DL +T ++VD+
Sbjct: 1166 GGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDD 1225
Query: 390 LQKSVDP--QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCH 446
VDP + P+ G+C + +G + C CP G+ G C D +EC CD
Sbjct: 1226 CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV-----GERCEGDVNECLSNPCDAR 1280
Query: 447 PAADCINLPGSFQCRCRDGWRGDGATCEDV-DEC----LTNNGGCHPRATCANTDGSFRC 501
+C+ F C CR G G CE V + C N G C A +NT F C
Sbjct: 1281 GTQNCVQRVNDFHCECRAG--HTGRRCESVINGCKGKPCKNGGTC---AVASNTARGFIC 1335
Query: 502 LCDTGYKG 509
C G++G
Sbjct: 1336 KCPAGFEG 1343
Score = 128 bits (309), Expect = 5e-29
Identities = 123/484 (25%), Positives = 198/484 (40%), Gaps = 80/484 (16%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
++++NEC P C HG C+N G + C C GY S + D+++C C +G
Sbjct: 868 EVDINECVLSP--CRHGASCQNTHGXYRCHCQAGY---SGRNCETDIDDCR--PNPCHNG 920
Query: 175 -DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PG++ + DI+ECA +D G C + S+ C C G
Sbjct: 921 GSCTDGINTAFCDCLPGFRGTFCEE---DINECA-SDPCRNGANCTDCVDSYTCTCPAGF 976
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
+ D E S +G G C + + ++ C+C G+ S + H
Sbjct: 977 SGIHCENNTPDCTESSCFNG----GTCVDGINSFTCLCPPGFTGSYCQ-HVVNECDSRPC 1031
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQCRNTVGSYTC 352
+C + G + CTC +G+ G +C+++ + PC GG+C T Y C
Sbjct: 1032 LLG--GTCQDGRGLHRCTCPQGY----TGPNCQNLVHWCDSS-PCKNGGKCWQTHTQYRC 1084
Query: 353 TCTDGL------VPSAA----------GAKPTCQDIDECADLISTIIMM-----SVDELQ 391
C G VPS + CQ C D +T + +
Sbjct: 1085 ECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE 1144
Query: 392 KSVDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAA 449
VD P C G+ C + +G + C+C GY G C+++ DEC + C
Sbjct: 1145 DLVDECSPSPCQNGATCTDYLGGYSCKCVAGY-----HGVNCSEEIDECL--SHPCQNGG 1197
Query: 450 DCINLPGSFQCRCRDGWRGDGATCE-DVDEC------LTNNGGCHPRATCANTDGSFRCL 502
C++LP +++C C G +G CE +VD+C ++ + C TC + G + C
Sbjct: 1198 TCLDLPNTYKCSCPRGTQG--VHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCT 1255
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGFTRAAD 561
C G+ G+ C D++EC ++P +C + C+C G T
Sbjct: 1256 CPPGFVGER-------CE---GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT---- 1301
Query: 562 GRSC 565
GR C
Sbjct: 1302 GRRC 1305
Score = 115 bits (277), Expect = 4e-25
Identities = 108/364 (29%), Positives = 145/364 (39%), Gaps = 71/364 (19%)
Query: 206 CADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSN-GAC--- 260
C+ C GG+C G+ C CG G + P C+D + C T C N G C
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCG-GAFVGP---RCQDPNPCLSTP--CKNAGTCHVV 77
Query: 261 -ENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC-VNTPGSYHCTCREGWHL 318
+ Y C C G++ + R +C + T Y C C GW
Sbjct: 78 DRRGVADYACSCALGFSGPLCLT--PLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGW-- 133
Query: 319 RADGRSCRDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTC-QDIDECA 376
G+SC+ D CA + PC GGQC SY C C PS G PTC QD++EC
Sbjct: 134 --SGKSCQQADPCA--SNPCANGGQCLPFEASYICHCP----PSFHG--PTCRQDVNECG 183
Query: 377 DLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGP-ACTD 434
Q P LC G+CHN +GS+ C C ++ + P
Sbjct: 184 --------------------QKPRLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCS 223
Query: 435 DDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCAN 494
C+ G C P D + +C C G+ G E++D+C NN C C +
Sbjct: 224 PSPCQNGG-TCRPTGDV-----THECACLPGFTGQNCE-ENIDDCPGNN--CKNGGACVD 274
Query: 495 TDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCD 553
++ C C + G Y D+DEC P C+N G C NT GGY C C
Sbjct: 275 GVNTYNCPCPPEWTGQ----------YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCV 324
Query: 554 VGFT 557
G+T
Sbjct: 325 NGWT 328
Score = 113 bits (272), Expect = 2e-24
Identities = 114/430 (26%), Positives = 168/430 (39%), Gaps = 62/430 (14%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYE-KDSKN--HTCVDVNECEIVDGVCG 172
Q VNEC + P L G G C++ G C C GY + +N H C D + C+
Sbjct: 1020 QHVVNECDSRPCLLG-GTCQDGRGLHRCTCPQGYTGPNCQNLVHWC-DSSPCK------N 1071
Query: 173 DGDCHNTEGSFTCHCRPGYKA--DDFSKICVDID---ECADNDALCR-GGRCVNTAGSFR 226
G C T + C C G+ D + ++ + D LC+ GG CV+ +
Sbjct: 1072 GGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH 1131
Query: 227 CECGHGMELAPDRLSCKD-IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHX 284
C C G + C+D +DECS + C NGA C + +G Y C C GY
Sbjct: 1132 CRCQAGYTGS----YCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 1185
Query: 285 XXXXXXXXXXXRCQH--SCVNTPGSYHCTC---REGWHLRADGRSCRD-IDECAGGARPC 338
CQ+ +C++ P +Y C+C +G H + C +D + +
Sbjct: 1186 DECLSHP-----CQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCF 1240
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAA-GAKPTC-------QDIDECADLISTI-IMMSVDE 389
G C + VG Y+CTC G V G C + C ++
Sbjct: 1241 NNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH 1300
Query: 390 LQKSVDPQIPELCG-----AGSC---HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
+ + I G G+C NT F+C+CP G+ +G C ++D G
Sbjct: 1301 TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF-----EGATC-ENDARTCG 1354
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGS--F 499
+ C CI+ P S C C + G CL N C+ + TC T S +
Sbjct: 1355 SLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGN-PCYNQGTCEPTSESPFY 1413
Query: 500 RCLCDTGYKG 509
RCLC + G
Sbjct: 1414 RCLCPAKFNG 1423
>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 174 bits (424), Expect = 6e-43
Identities = 140/461 (30%), Positives = 199/461 (43%), Gaps = 75/461 (16%)
Query: 127 GLC-GHGRCRN-LLGG---FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CH-NT 179
G C G G C++ ++ G F+C C G+ + C + C + C G C
Sbjct: 85 GPCAGRGVCQSSVVAGTARFSCRCPRGF----RGPDCSLPDPC--LSSPCAHGARCSVGP 138
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDR 239
+G F C C PGY+ D+DEC + GG C+NT GSFRC+C G P
Sbjct: 139 DGRFLCSCPPGYQGRSCRS---DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY-TGP-- 192
Query: 240 LSCKDIDECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
C++ C NG Q G TY C C G+ + + RC
Sbjct: 193 -LCEN-PAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVN-----VDDCPGHRC 245
Query: 298 QH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGSYTCT 353
+ +CV+ +Y+C C W G+ C D+DEC C GG C NT+G ++C
Sbjct: 246 LNGGTCVDGVNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCV 301
Query: 354 CTDGLVPSAAG------AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
C +G + A C C D +++ + + + + + C + C
Sbjct: 302 CVNGWTGESCSQNIDDCATAVCFHGATCHDRVAS-FYCACPMGKTGLLCHLDDACVSNPC 360
Query: 408 H-------NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSF 458
H N + G +C CP G++ G AC D DEC +G C C+N GSF
Sbjct: 361 HEDAICDTNPVNGRAICTCPPGFT-----GGACDQDVDECSIGANPCEHLGRCVNTQGSF 415
Query: 459 QCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C+C G+ G CE DV+ECL +G C +ATC + G F C+C G+ G
Sbjct: 416 LCQCGRGY--TGPRCETDVNECL--SGPCRNQATCLDRIGQFTCICMAGFTG-------- 463
Query: 518 CCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
Y VDIDEC + P C NG C + G+ C C GF+
Sbjct: 464 --TYCEVDIDECQSSP--CVNGGVCKDRVNGFSCTCPSGFS 500
Score = 165 bits (400), Expect = 5e-40
Identities = 147/482 (30%), Positives = 208/482 (43%), Gaps = 90/482 (18%)
Query: 116 QMEVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
Q +V+ECA P CG HG C NL G F+C C GY S + D+N+C+ + G G
Sbjct: 808 QQDVDECAG-PAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ---DINDCDPNPCLNG-G 862
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + GSF+C C PG+ ++ D+DEC N C G C + SF C C G
Sbjct: 863 SCQDGVGSFSCSCLPGFAGPRCAR---DVDECLSNP--CGPGTCTDHVASFTCTCPPGY- 916
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
C+ D+ +CS +S C NG C + + ++ C+C GY + +
Sbjct: 917 ---GGFHCEQDLPDCSPSS--CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRP- 970
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPC-GGGQCRNTVG 348
C H C + CTC E + G C+ +D C+ +PC GG+C T G
Sbjct: 971 ----CLHGGVCSAAHPGFRCTCLESF----TGPQCQTLVDWCS--RQPCQNGGRCVQT-G 1019
Query: 349 SYTCTCTDGL---------VPSAAGA-------KPTCQDIDECADLISTIIMMSVD---- 388
+Y C C G +P A + CQ +C D S+ + +
Sbjct: 1020 AY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTG 1078
Query: 389 -ELQKSVDPQIPELCG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
++ VDP + + C G+C +G ++C+C GY+ G C DD DEC + C
Sbjct: 1079 SHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYN-----GDNCEDDVDEC--ASQPC 1131
Query: 446 HPAADCINLPGSFQCRCRDGWRGDGATCE-DVDEC-----LTNNGGCHPRATCANTDGSF 499
CI+L + C C G G CE + D+C L + C TC + G F
Sbjct: 1132 QHGGSCIDLVARYLCSCPPGTLG--VLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGF 1189
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH---CSNTP-GGYECDCDVG 555
RC C GY GLR C DI+EC + C H C P GG+ C C G
Sbjct: 1190 RCTCPPGYT----GLR---CE---ADINECRSG--ACHAAHTRDCLQDPGGGFRCLCHAG 1237
Query: 556 FT 557
F+
Sbjct: 1238 FS 1239
Score = 158 bits (383), Expect = 6e-38
Identities = 134/450 (29%), Positives = 187/450 (41%), Gaps = 81/450 (18%)
Query: 118 EVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC C HG C N G F C C GY + V +G G C
Sbjct: 158 DVDECRVGEP-CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNG----GTC 212
Query: 177 HNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+ + ++ C C PG++ + V++D+C + L GG CV+ ++ C+C
Sbjct: 213 RQSGDLTYDCACLPGFEGQNCE---VNVDDCPGHRCL-NGGTCVDGVNTYNCQCPPEW-- 266
Query: 236 APDRLSCKDIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ +D+DEC + C N G C N +G + CVC G+ + +
Sbjct: 267 -TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAV--- 322
Query: 295 XRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT---VGS 349
C H +C + S++C C G G C D C + PC +T G
Sbjct: 323 --CFHGATCHDRVASFYCACPMG----KTGLLCHLDDACV--SNPCHEDAICDTNPVNGR 374
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
CTC G A QD+DEC +I + L G C N
Sbjct: 375 AICTCPPGFTGGACD-----QDVDEC-----SIGANPCEHL--------------GRCVN 410
Query: 410 TIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG 468
T GSF+CQC GY+ GP C TD +EC G C A C++ G F C C G+
Sbjct: 411 TQGSFLCQCGRGYT-----GPRCETDVNECLSG--PCRNQATCLDRIGQFTCICMAGF-- 461
Query: 469 DGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
G CE D+DEC + C C + F C C +G+ G + C +D+D
Sbjct: 462 TGTYCEVDIDEC--QSSPCVNGGVCKDRVNGFSCTCPSGFSG------STC----QLDVD 509
Query: 528 ECANDPTLCENG-HCSNTPGGYECDCDVGF 556
ECA+ P C NG C + P GYEC C GF
Sbjct: 510 ECASTP--CRNGAKCVDQPDGYECRCAEGF 537
Score = 157 bits (382), Expect = 7e-38
Identities = 129/462 (27%), Positives = 188/462 (40%), Gaps = 68/462 (14%)
Query: 116 QMEVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC + P C C + +G FTC C G+ + + VD++EC+ V G G
Sbjct: 429 ETDVNECLSGP--CRNQATCLDRIGQFTCICMAGF---TGTYCEVDIDECQSSPCVNG-G 482
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRCECGHGM 233
C + F+C C G+ S +D+DECA CR G +CV+ + C C G
Sbjct: 483 VCKDRVNGFSCTCPSGFSG---STCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGF 537
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
E L +++D+CS C +G C + + ++ C C GY + +S
Sbjct: 538 E---GTLCDRNVDDCSPDP--CHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQP-- 590
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSY 350
C+H C++ Y C C G G +C +ID+CA + PC G CR+ + Y
Sbjct: 591 ---CRHGGKCLDLVDKYLCRCPSG----TTGVNCEVNIDDCA--SNPCTFGVCRDGINRY 641
Query: 351 TCTCTDGLVPSAAG------AKPTCQDIDECADLISTIIMM----SVDEL-QKSVDPQIP 399
C C G A C + C D + + S+ L P
Sbjct: 642 DCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAH 701
Query: 400 ELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD---DECELGTCDCHPAADCINLPG 456
E C G C++ G F C C G+S GP C+ D CE + C C +
Sbjct: 702 EPCSHGICYDAPGGFRCVCEPGWS-----GPRCSQSLARDACE--SQPCRAGGTCSSDGM 754
Query: 457 SFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFR-CLCDTGYKGDGYGLR 515
F C C G +G CE + C N C C + G C C G++G
Sbjct: 755 GFHCTCPPGVQG--RQCELLSPCTPNP--CEHGGRCESAPGQLPVCSCPQGWQGPR---- 806
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
C D+DECA +G C+N G + C C G+T
Sbjct: 807 ---CQQ---DVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT 842
Score = 153 bits (371), Expect = 2e-36
Identities = 129/460 (28%), Positives = 186/460 (40%), Gaps = 67/460 (14%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
Q++V+ECA+ P C +G +C + G+ C C G+E T D N + C G
Sbjct: 505 QLDVDECASTP--CRNGAKCVDQPDGYECRCAEGFEG-----TLCDRNVDDCSPDPCHHG 557
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGM 233
C + SF+C C PGY ++ +DEC CR GG+C++ + C C G
Sbjct: 558 RCVDGIASFSCACAPGYTG---TRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSGT 612
Query: 234 ELAPDRLSCK-DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
++C+ +ID+C+ S C+ G C + + Y CVC G+
Sbjct: 613 T----GVNCEVNIDDCA--SNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPC 666
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
SCV+ + C C G CA PC G C + G + C
Sbjct: 667 GEGG---SCVDGENGFRCLCPPG---SLPPLCLPPSHPCAH--EPCSHGICYDAPGGFRC 718
Query: 353 TCTDG---------LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQ----KSVDPQIP 399
C G L A ++P C+ C+ +Q + + P P
Sbjct: 719 VCEPGWSGPRCSQSLARDACESQP-CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTP 777
Query: 400 ELCG-AGSCHNTIGSF-VCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPG 456
C G C + G VC CP G+ QGP C D DEC G C P C NL G
Sbjct: 778 NPCEHGGRCESAPGQLPVCSCPQGW-----QGPRCQQDVDECA-GPAPCGPHGICTNLAG 831
Query: 457 SFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
SF C C G+ G +D+++C N C +C + GSF C C G+ G
Sbjct: 832 SFSCTCHGGYTGPSCD-QDINDCDPN--PCLNGGSCQDGVGSFSCSCLPGFAGPR----- 883
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
C D+DEC ++P C G C++ + C C G+
Sbjct: 884 --CAR---DVDECLSNP--CGPGTCTDHVASFTCTCPPGY 916
Score = 144 bits (350), Expect = 6e-34
Identities = 126/459 (27%), Positives = 193/459 (42%), Gaps = 68/459 (14%)
Query: 119 VNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEK--DSKNHTCVDVNECEIVDGVCGDGD 175
+++CA +C HG C + + F C C G + CV N C D +C D
Sbjct: 315 IDDCAT--AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVS-NPCH-EDAIC---D 367
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGME 234
+ G C C PG+ + D+DEC+ C GRCVNT GSF C+CG G
Sbjct: 368 TNPVNGRAICTCPPGFTGGACDQ---DVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY- 423
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
P C+ D++EC SG C N A C +++G + C+C G+ + +
Sbjct: 424 TGP---RCETDVNEC--LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPC 478
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C + + CTC G+ G +C+ D+DECA + PC G +C + Y
Sbjct: 479 VNGGV---CKDRVNGFSCTCPSGF----SGSTCQLDVDECA--STPCRNGAKCVDQPDGY 529
Query: 351 TCTCTDGLVPSAA-----GAKPTCQDIDECADLISTIIMMSV-----DELQKSVDPQIPE 400
C C +G + P C D I++ + VD +
Sbjct: 530 ECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQ 589
Query: 401 LC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSF 458
C G C + + ++C+CP G + G C + D+C C D IN +
Sbjct: 590 PCRHGGKCLDLVDKYLCRCPSGTT-----GVNCEVNIDDCASNPCTFGVCRDGIN---RY 641
Query: 459 QCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C C+ G+ G E ++EC ++ C +C + + FRCLC G L +C
Sbjct: 642 DCVCQPGFTGPLCNVE-INECASS--PCGEGGSCVDGENGFRCLCPPG------SLPPLC 692
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
S CA++P C +G C + PGG+ C C+ G++
Sbjct: 693 LPPS----HPCAHEP--CSHGICYDAPGGFRCVCEPGWS 725
Score = 139 bits (337), Expect = 2e-32
Identities = 135/471 (28%), Positives = 196/471 (41%), Gaps = 69/471 (14%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++N+C P L G G C++ +G F+C C PG+ + DV+EC + CG G C
Sbjct: 849 DINDCDPNPCLNG-GSCQDGVGSFSCSCLPGF---AGPRCARDVDEC--LSNPCGPGTCT 902
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
+ SFTC C PGY + D+ +C+ + GG CV+ SF C C G A
Sbjct: 903 DHVASFTCTCPPGYGGFHCEQ---DLPDCSPSSCF-NGGTCVDGVNSFSCLCRPGYTGA- 957
Query: 238 DRLSCK-DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
C+ + D C ++ G C ++C C E + ++
Sbjct: 958 ---HCQHEADPC-LSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQT-----LVDWCSRQP 1008
Query: 297 CQHS--CVNTPGSYHCTCREGWHLR-ADGRS--CRDIDECAGGA--RPC-GGGQCRNTVG 348
CQ+ CV T G+Y C C GW R D RS CR+ G + C GGQC +
Sbjct: 1009 CQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDS 1066
Query: 349 SYTCTCTDGLVPSAAG-------AKPTCQDIDECADLISTIIMMSV-----DELQKSVDP 396
S+ C C +G S A+P CQ C + + + D + VD
Sbjct: 1067 SHYCVCPEGRTGSHCEQEVDPCLAQP-CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDE 1125
Query: 397 QIPELCG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACT-DDDECELGT-CDCHPAA---- 449
+ C GSC + + ++C CP G G C ++D+C G D P
Sbjct: 1126 CASQPCQHGGSCIDLVARYLCSCPPG-----TLGVLCEINEDDCGPGPPLDSGPRCLHNG 1180
Query: 450 DCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRAT--CA-NTDGSFRCLCDT 505
C++L G F+C C G+ G CE D++EC +G CH T C + G FRCLC
Sbjct: 1181 TCVDLVGGFRCTCPPGYTG--LRCEADINEC--RSGACHAAHTRDCLQDPGGGFRCLCHA 1236
Query: 506 GYKGDG-YGLRTVCCVYSCVDIDECANDP----TLCENGHCSNTPGGYECD 551
G+ G + + C C +C P L HC+ G C+
Sbjct: 1237 GFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1287
Score = 133 bits (322), Expect = 1e-30
Identities = 132/476 (27%), Positives = 181/476 (38%), Gaps = 78/476 (16%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC + P CG G C + + FTC C PGY H D+ +C G G C
Sbjct: 887 DVDECLSNP--CGPGTCTDHVASFTCTCPPGY---GGFHCEQDLPDCSPSSCFNG-GTCV 940
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
+ SF+C CRPGY + D C L GG C FRC C P
Sbjct: 941 DGVNSFSCLCRPGYTGAHCQH---EADPCLSRPCL-HGGVCSAAHPGFRCTCLESFT-GP 995
Query: 238 DRLSCKD-IDECSITSGICSNGACENQMGTYQCVCDEGYAQS-----TVKSHXXXXXXXX 291
C+ +D CS C NG Q G Y C+C G++ ++
Sbjct: 996 Q---CQTLVDWCSRQP--CQNGGRCVQTGAY-CLCPPGWSGRLCDIRSLPCREAAAQIGV 1049
Query: 292 XXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVG 348
CQ CV+ S++C C EG R +++D C A+PC GG CR +G
Sbjct: 1050 RLEQLCQAGGQCVDEDSSHYCVCPEG---RTGSHCEQEVDPCL--AQPCQHGGTCRGYMG 1104
Query: 349 SYTCTCTDGLVPSAAG------AKPTCQDIDECADLISTI----------IMMSVDELQK 392
Y C C G A CQ C DL++ ++ ++E
Sbjct: 1105 GYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDC 1164
Query: 393 SVDPQI---PELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
P + P G+C + +G F C CP GY+ G C D +EC G C
Sbjct: 1165 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT-----GLRCEADINECRSGACHAAHT 1219
Query: 449 ADCINLPGS-FQCRCRDGWRGDGATCEDV-DECLTNNGGCHPRATCANTDG-----SFRC 501
DC+ PG F+C C G+ G C+ V C + C C + G +F C
Sbjct: 1220 RDCLQDPGGGFRCLCHAGF--SGPRCQTVLSPC--ESQPCQHGGQCRPSPGPGGGLTFTC 1275
Query: 502 LCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
C + +G R SC ++ P C TP G C C G +
Sbjct: 1276 HCAQPF----WGPRCERVARSCRELQCPVGVP-------CQQTPRGPRCACPPGLS 1320
Score = 86.6 bits (205), Expect = 2e-16
Identities = 78/266 (29%), Positives = 114/266 (42%), Gaps = 51/266 (19%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ EV+ C A P C HG CR +GG+ C+C PGY D+ DV+EC G G
Sbjct: 1082 EQEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGYNGDNCED---DVDECASQPCQHG-G 1135
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKIC-VDIDECA-----DNDALC-RGGRCVNTAGSFRC 227
C + + C C PG +C ++ D+C D+ C G CV+ G FRC
Sbjct: 1136 SCIDLVARYLCSCPPG----TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRC 1191
Query: 228 ECGHGMELAPDRLSCK-DIDECSITSGIC----SNGACENQMGTYQCVCDEGYAQSTVKS 282
C G L C+ DI+EC SG C + ++ G ++C+C G++ ++
Sbjct: 1192 TCPPGY----TGLRCEADINEC--RSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQT 1245
Query: 283 HXXXXXXXXXXXXRCQH--SCVNTPG-----SYHCTCREG-WHLRAD--GRSCRDIDECA 332
CQH C +PG ++ C C + W R + RSCR++ +C
Sbjct: 1246 -----VLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCREL-QCP 1299
Query: 333 GGARPCGGGQCRNTVGSYTCTCTDGL 358
G C+ T C C GL
Sbjct: 1300 VGV------PCQQTPRGPRCACPPGL 1319
Score = 80.2 bits (189), Expect = 2e-14
Identities = 93/396 (23%), Positives = 141/396 (35%), Gaps = 57/396 (14%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGY 191
G+C + C C G + +H +V+ C + G C G + C C PGY
Sbjct: 1059 GQCVDEDSSHYCVCPEGR---TGSHCEQEVDPC-LAQPCQHGGTCRGYMGGYMCECLPGY 1114
Query: 192 KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECS- 249
D+ D+DECA GG C++ + C C G + C+ + D+C
Sbjct: 1115 NGDNCED---DVDECASQPCQ-HGGSCIDLVARYLCSCPPGTL----GVLCEINEDDCGP 1166
Query: 250 ---ITSG--ICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNT 304
+ SG NG C + +G ++C C GY ++ + C+
Sbjct: 1167 GPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTR-DCLQD 1225
Query: 305 PGS-YHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVG-----SYTCTCTD 356
PG + C C G+ G C+ + C ++PC GGQCR + G ++TC C
Sbjct: 1226 PGGGFRCLCHAGF----SGPRCQTVLSPCE--SQPCQHGGQCRPSPGPGGGLTFTCHCAQ 1279
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
P C+ + + + + + + P SC + GS
Sbjct: 1280 PFWG------PRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGS--- 1330
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
P G S C L C PA L F+C C GW G
Sbjct: 1331 --PPGASNASCAAAPC-------LHGGSCRPAP----LAPFFRCACAQGWTGPRCEAPAA 1377
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
++ C PRA C G RC + G G+
Sbjct: 1378 APEVSEEPRC-PRAACQAKRGDQRCDRECNSPGCGW 1412
Score = 78.2 bits (184), Expect = 7e-14
Identities = 73/225 (32%), Positives = 91/225 (40%), Gaps = 35/225 (15%)
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGS 406
G+ C DG P A G + T E A L V E + DP C G G
Sbjct: 37 GAAAPPCLDGS-PCANGGRCTQLPSREAACLCPP---GWVGERCQLEDPCHSGPCAGRGV 92
Query: 407 CHNTI----GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
C +++ F C+CP G+ +GP C+ D C C H A + G F C C
Sbjct: 93 CQSSVVAGTARFSCRCPRGF-----RGPDCSLPDPCLSSPC-AHGARCSVGPDGRFLCSC 146
Query: 463 RDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G++G DVDEC C TC NT GSFRC C GY G C
Sbjct: 147 PPGYQGRSCR-SDVDECRVGEP-CRHGGTCLNTPGSFRCQCPAGYTGP-------LCENP 197
Query: 523 CVDIDECANDPTLCENGHCSNTPGG--YECDCDVGFTRAADGRSC 565
V CA P+ C NG G Y+C C GF +G++C
Sbjct: 198 AV---PCA--PSPCRNGGTCRQSGDLTYDCACLPGF----EGQNC 233
>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 174 bits (424), Expect = 6e-43
Identities = 140/461 (30%), Positives = 199/461 (43%), Gaps = 75/461 (16%)
Query: 127 GLC-GHGRCRN-LLGG---FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CH-NT 179
G C G G C++ ++ G F+C C G+ + C + C + C G C
Sbjct: 85 GPCAGRGVCQSSVVAGTARFSCRCPRGF----RGPDCSLPDPC--LSSPCAHGARCSVGP 138
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDR 239
+G F C C PGY+ D+DEC + GG C+NT GSFRC+C G P
Sbjct: 139 DGRFLCSCPPGYQGRSCRS---DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY-TGP-- 192
Query: 240 LSCKDIDECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
C++ C NG Q G TY C C G+ + + RC
Sbjct: 193 -LCEN-PAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVN-----VDDCPGHRC 245
Query: 298 QH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGSYTCT 353
+ +CV+ +Y+C C W G+ C D+DEC C GG C NT+G ++C
Sbjct: 246 LNGGTCVDGVNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCV 301
Query: 354 CTDGLVPSAAG------AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
C +G + A C C D +++ + + + + + C + C
Sbjct: 302 CVNGWTGESCSQNIDDCATAVCFHGATCHDRVAS-FYCACPMGKTGLLCHLDDACVSNPC 360
Query: 408 H-------NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSF 458
H N + G +C CP G++ G AC D DEC +G C C+N GSF
Sbjct: 361 HEDAICDTNPVNGRAICTCPPGFT-----GGACDQDVDECSIGANPCEHLGRCVNTQGSF 415
Query: 459 QCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C+C G+ G CE DV+ECL +G C +ATC + G F C+C G+ G
Sbjct: 416 LCQCGRGY--TGPRCETDVNECL--SGPCRNQATCLDRIGQFTCICMAGFTG-------- 463
Query: 518 CCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
Y VDIDEC + P C NG C + G+ C C GF+
Sbjct: 464 --TYCEVDIDECQSSP--CVNGGVCKDRVNGFSCTCPSGFS 500
Score = 165 bits (400), Expect = 5e-40
Identities = 147/482 (30%), Positives = 208/482 (43%), Gaps = 90/482 (18%)
Query: 116 QMEVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
Q +V+ECA P CG HG C NL G F+C C GY S + D+N+C+ + G G
Sbjct: 808 QQDVDECAG-PAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ---DINDCDPNPCLNG-G 862
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + GSF+C C PG+ ++ D+DEC N C G C + SF C C G
Sbjct: 863 SCQDGVGSFSCSCLPGFAGPRCAR---DVDECLSNP--CGPGTCTDHVASFTCTCPPGY- 916
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
C+ D+ +CS +S C NG C + + ++ C+C GY + +
Sbjct: 917 ---GGFHCEQDLPDCSPSS--CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRP- 970
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPC-GGGQCRNTVG 348
C H C + CTC E + G C+ +D C+ +PC GG+C T G
Sbjct: 971 ----CLHGGVCSAAHPGFRCTCLESF----TGPQCQTLVDWCS--RQPCQNGGRCVQT-G 1019
Query: 349 SYTCTCTDGL---------VPSAAGA-------KPTCQDIDECADLISTIIMMSVD---- 388
+Y C C G +P A + CQ +C D S+ + +
Sbjct: 1020 AY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTG 1078
Query: 389 -ELQKSVDPQIPELCG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
++ VDP + + C G+C +G ++C+C GY+ G C DD DEC + C
Sbjct: 1079 SHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYN-----GDNCEDDVDEC--ASQPC 1131
Query: 446 HPAADCINLPGSFQCRCRDGWRGDGATCE-DVDEC-----LTNNGGCHPRATCANTDGSF 499
CI+L + C C G G CE + D+C L + C TC + G F
Sbjct: 1132 QHGGSCIDLVARYLCSCPPGTLG--VLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGF 1189
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH---CSNTP-GGYECDCDVG 555
RC C GY GLR C DI+EC + C H C P GG+ C C G
Sbjct: 1190 RCTCPPGYT----GLR---CE---ADINECRSG--ACHAAHTRDCLQDPGGGFRCLCHAG 1237
Query: 556 FT 557
F+
Sbjct: 1238 FS 1239
Score = 158 bits (383), Expect = 6e-38
Identities = 134/450 (29%), Positives = 187/450 (41%), Gaps = 81/450 (18%)
Query: 118 EVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC C HG C N G F C C GY + V +G G C
Sbjct: 158 DVDECRVGEP-CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNG----GTC 212
Query: 177 HNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+ + ++ C C PG++ + V++D+C + L GG CV+ ++ C+C
Sbjct: 213 RQSGDLTYDCACLPGFEGQNCE---VNVDDCPGHRCL-NGGTCVDGVNTYNCQCPPEW-- 266
Query: 236 APDRLSCKDIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ +D+DEC + C N G C N +G + CVC G+ + +
Sbjct: 267 -TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAV--- 322
Query: 295 XRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT---VGS 349
C H +C + S++C C G G C D C + PC +T G
Sbjct: 323 --CFHGATCHDRVASFYCACPMG----KTGLLCHLDDACV--SNPCHEDAICDTNPVNGR 374
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
CTC G A QD+DEC +I + L G C N
Sbjct: 375 AICTCPPGFTGGACD-----QDVDEC-----SIGANPCEHL--------------GRCVN 410
Query: 410 TIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG 468
T GSF+CQC GY+ GP C TD +EC G C A C++ G F C C G+
Sbjct: 411 TQGSFLCQCGRGYT-----GPRCETDVNECLSG--PCRNQATCLDRIGQFTCICMAGF-- 461
Query: 469 DGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
G CE D+DEC + C C + F C C +G+ G + C +D+D
Sbjct: 462 TGTYCEVDIDEC--QSSPCVNGGVCKDRVNGFSCTCPSGFSG------STC----QLDVD 509
Query: 528 ECANDPTLCENG-HCSNTPGGYECDCDVGF 556
ECA+ P C NG C + P GYEC C GF
Sbjct: 510 ECASTP--CRNGAKCVDQPDGYECRCAEGF 537
Score = 157 bits (382), Expect = 7e-38
Identities = 129/462 (27%), Positives = 188/462 (40%), Gaps = 68/462 (14%)
Query: 116 QMEVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC + P C C + +G FTC C G+ + + VD++EC+ V G G
Sbjct: 429 ETDVNECLSGP--CRNQATCLDRIGQFTCICMAGF---TGTYCEVDIDECQSSPCVNG-G 482
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRCECGHGM 233
C + F+C C G+ S +D+DECA CR G +CV+ + C C G
Sbjct: 483 VCKDRVNGFSCTCPSGFSG---STCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGF 537
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
E L +++D+CS C +G C + + ++ C C GY + +S
Sbjct: 538 E---GTLCDRNVDDCSPDP--CHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQP-- 590
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSY 350
C+H C++ Y C C G G +C +ID+CA + PC G CR+ + Y
Sbjct: 591 ---CRHGGKCLDLVDKYLCRCPSG----TTGVNCEVNIDDCA--SNPCTFGVCRDGINRY 641
Query: 351 TCTCTDGLVPSAAG------AKPTCQDIDECADLISTIIMM----SVDEL-QKSVDPQIP 399
C C G A C + C D + + S+ L P
Sbjct: 642 DCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAH 701
Query: 400 ELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD---DECELGTCDCHPAADCINLPG 456
E C G C++ G F C C G+S GP C+ D CE + C C +
Sbjct: 702 EPCSHGICYDAPGGFRCVCEPGWS-----GPRCSQSLARDACE--SQPCRAGGTCSSDGM 754
Query: 457 SFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFR-CLCDTGYKGDGYGLR 515
F C C G +G CE + C N C C + G C C G++G
Sbjct: 755 GFHCTCPPGVQG--RQCELLSPCTPNP--CEHGGRCESAPGQLPVCSCPQGWQGPR---- 806
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
C D+DECA +G C+N G + C C G+T
Sbjct: 807 ---CQQ---DVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT 842
Score = 153 bits (371), Expect = 2e-36
Identities = 129/460 (28%), Positives = 186/460 (40%), Gaps = 67/460 (14%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
Q++V+ECA+ P C +G +C + G+ C C G+E T D N + C G
Sbjct: 505 QLDVDECASTP--CRNGAKCVDQPDGYECRCAEGFEG-----TLCDRNVDDCSPDPCHHG 557
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGM 233
C + SF+C C PGY ++ +DEC CR GG+C++ + C C G
Sbjct: 558 RCVDGIASFSCACAPGYTG---TRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSGT 612
Query: 234 ELAPDRLSCK-DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
++C+ +ID+C+ S C+ G C + + Y CVC G+
Sbjct: 613 T----GVNCEVNIDDCA--SNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPC 666
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
SCV+ + C C G CA PC G C + G + C
Sbjct: 667 GEGG---SCVDGENGFRCLCPPG---SLPPLCLPPSHPCAH--EPCSHGICYDAPGGFRC 718
Query: 353 TCTDG---------LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQ----KSVDPQIP 399
C G L A ++P C+ C+ +Q + + P P
Sbjct: 719 VCEPGWSGPRCSQSLARDACESQP-CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTP 777
Query: 400 ELCG-AGSCHNTIGSF-VCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPG 456
C G C + G VC CP G+ QGP C D DEC G C P C NL G
Sbjct: 778 NPCEHGGRCESAPGQLPVCSCPQGW-----QGPRCQQDVDECA-GPAPCGPHGICTNLAG 831
Query: 457 SFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
SF C C G+ G +D+++C N C +C + GSF C C G+ G
Sbjct: 832 SFSCTCHGGYTGPSCD-QDINDCDPN--PCLNGGSCQDGVGSFSCSCLPGFAGPR----- 883
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
C D+DEC ++P C G C++ + C C G+
Sbjct: 884 --CAR---DVDECLSNP--CGPGTCTDHVASFTCTCPPGY 916
Score = 144 bits (350), Expect = 6e-34
Identities = 126/459 (27%), Positives = 193/459 (42%), Gaps = 68/459 (14%)
Query: 119 VNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEK--DSKNHTCVDVNECEIVDGVCGDGD 175
+++CA +C HG C + + F C C G + CV N C D +C D
Sbjct: 315 IDDCAT--AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVS-NPCH-EDAIC---D 367
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGME 234
+ G C C PG+ + D+DEC+ C GRCVNT GSF C+CG G
Sbjct: 368 TNPVNGRAICTCPPGFTGGACDQ---DVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY- 423
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
P C+ D++EC SG C N A C +++G + C+C G+ + +
Sbjct: 424 TGP---RCETDVNEC--LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPC 478
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C + + CTC G+ G +C+ D+DECA + PC G +C + Y
Sbjct: 479 VNGGV---CKDRVNGFSCTCPSGF----SGSTCQLDVDECA--STPCRNGAKCVDQPDGY 529
Query: 351 TCTCTDGLVPSAA-----GAKPTCQDIDECADLISTIIMMSV-----DELQKSVDPQIPE 400
C C +G + P C D I++ + VD +
Sbjct: 530 ECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQ 589
Query: 401 LC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSF 458
C G C + + ++C+CP G + G C + D+C C D IN +
Sbjct: 590 PCRHGGKCLDLVDKYLCRCPSGTT-----GVNCEVNIDDCASNPCTFGVCRDGIN---RY 641
Query: 459 QCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C C+ G+ G E ++EC ++ C +C + + FRCLC G L +C
Sbjct: 642 DCVCQPGFTGPLCNVE-INECASS--PCGEGGSCVDGENGFRCLCPPG------SLPPLC 692
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
S CA++P C +G C + PGG+ C C+ G++
Sbjct: 693 LPPS----HPCAHEP--CSHGICYDAPGGFRCVCEPGWS 725
Score = 139 bits (337), Expect = 2e-32
Identities = 135/471 (28%), Positives = 196/471 (41%), Gaps = 69/471 (14%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++N+C P L G G C++ +G F+C C PG+ + DV+EC + CG G C
Sbjct: 849 DINDCDPNPCLNG-GSCQDGVGSFSCSCLPGF---AGPRCARDVDEC--LSNPCGPGTCT 902
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
+ SFTC C PGY + D+ +C+ + GG CV+ SF C C G A
Sbjct: 903 DHVASFTCTCPPGYGGFHCEQ---DLPDCSPSSCF-NGGTCVDGVNSFSCLCRPGYTGA- 957
Query: 238 DRLSCK-DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
C+ + D C ++ G C ++C C E + ++
Sbjct: 958 ---HCQHEADPC-LSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQT-----LVDWCSRQP 1008
Query: 297 CQHS--CVNTPGSYHCTCREGWHLR-ADGRS--CRDIDECAGGA--RPC-GGGQCRNTVG 348
CQ+ CV T G+Y C C GW R D RS CR+ G + C GGQC +
Sbjct: 1009 CQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDS 1066
Query: 349 SYTCTCTDGLVPSAAG-------AKPTCQDIDECADLISTIIMMSV-----DELQKSVDP 396
S+ C C +G S A+P CQ C + + + D + VD
Sbjct: 1067 SHYCVCPEGRTGSHCEQEVDPCLAQP-CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDE 1125
Query: 397 QIPELCG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACT-DDDECELGT-CDCHPAA---- 449
+ C GSC + + ++C CP G G C ++D+C G D P
Sbjct: 1126 CASQPCQHGGSCIDLVARYLCSCPPG-----TLGVLCEINEDDCGPGPPLDSGPRCLHNG 1180
Query: 450 DCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRAT--CA-NTDGSFRCLCDT 505
C++L G F+C C G+ G CE D++EC +G CH T C + G FRCLC
Sbjct: 1181 TCVDLVGGFRCTCPPGYTG--LRCEADINEC--RSGACHAAHTRDCLQDPGGGFRCLCHA 1236
Query: 506 GYKGDG-YGLRTVCCVYSCVDIDECANDP----TLCENGHCSNTPGGYECD 551
G+ G + + C C +C P L HC+ G C+
Sbjct: 1237 GFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1287
Score = 133 bits (322), Expect = 1e-30
Identities = 132/476 (27%), Positives = 181/476 (38%), Gaps = 78/476 (16%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC + P CG G C + + FTC C PGY H D+ +C G G C
Sbjct: 887 DVDECLSNP--CGPGTCTDHVASFTCTCPPGY---GGFHCEQDLPDCSPSSCFNG-GTCV 940
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
+ SF+C CRPGY + D C L GG C FRC C P
Sbjct: 941 DGVNSFSCLCRPGYTGAHCQH---EADPCLSRPCL-HGGVCSAAHPGFRCTCLESFT-GP 995
Query: 238 DRLSCKD-IDECSITSGICSNGACENQMGTYQCVCDEGYAQS-----TVKSHXXXXXXXX 291
C+ +D CS C NG Q G Y C+C G++ ++
Sbjct: 996 Q---CQTLVDWCSRQP--CQNGGRCVQTGAY-CLCPPGWSGRLCDIRSLPCREAAAQIGV 1049
Query: 292 XXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVG 348
CQ CV+ S++C C EG R +++D C A+PC GG CR +G
Sbjct: 1050 RLEQLCQAGGQCVDEDSSHYCVCPEG---RTGSHCEQEVDPCL--AQPCQHGGTCRGYMG 1104
Query: 349 SYTCTCTDGLVPSAAG------AKPTCQDIDECADLISTI----------IMMSVDELQK 392
Y C C G A CQ C DL++ ++ ++E
Sbjct: 1105 GYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDC 1164
Query: 393 SVDPQI---PELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
P + P G+C + +G F C CP GY+ G C D +EC G C
Sbjct: 1165 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT-----GLRCEADINECRSGACHAAHT 1219
Query: 449 ADCINLPGS-FQCRCRDGWRGDGATCEDV-DECLTNNGGCHPRATCANTDG-----SFRC 501
DC+ PG F+C C G+ G C+ V C + C C + G +F C
Sbjct: 1220 RDCLQDPGGGFRCLCHAGF--SGPRCQTVLSPC--ESQPCQHGGQCRPSPGPGGGLTFTC 1275
Query: 502 LCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
C + +G R SC ++ P C TP G C C G +
Sbjct: 1276 HCAQPF----WGPRCERVARSCRELQCPVGVP-------CQQTPRGPRCACPPGLS 1320
Score = 86.6 bits (205), Expect = 2e-16
Identities = 78/266 (29%), Positives = 114/266 (42%), Gaps = 51/266 (19%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ EV+ C A P C HG CR +GG+ C+C PGY D+ DV+EC G G
Sbjct: 1082 EQEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGYNGDNCED---DVDECASQPCQHG-G 1135
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKIC-VDIDECA-----DNDALC-RGGRCVNTAGSFRC 227
C + + C C PG +C ++ D+C D+ C G CV+ G FRC
Sbjct: 1136 SCIDLVARYLCSCPPG----TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRC 1191
Query: 228 ECGHGMELAPDRLSCK-DIDECSITSGIC----SNGACENQMGTYQCVCDEGYAQSTVKS 282
C G L C+ DI+EC SG C + ++ G ++C+C G++ ++
Sbjct: 1192 TCPPGY----TGLRCEADINEC--RSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQT 1245
Query: 283 HXXXXXXXXXXXXRCQH--SCVNTPG-----SYHCTCREG-WHLRAD--GRSCRDIDECA 332
CQH C +PG ++ C C + W R + RSCR++ +C
Sbjct: 1246 -----VLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCREL-QCP 1299
Query: 333 GGARPCGGGQCRNTVGSYTCTCTDGL 358
G C+ T C C GL
Sbjct: 1300 VGV------PCQQTPRGPRCACPPGL 1319
Score = 80.2 bits (189), Expect = 2e-14
Identities = 93/396 (23%), Positives = 141/396 (35%), Gaps = 57/396 (14%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGY 191
G+C + C C G + +H +V+ C + G C G + C C PGY
Sbjct: 1059 GQCVDEDSSHYCVCPEGR---TGSHCEQEVDPC-LAQPCQHGGTCRGYMGGYMCECLPGY 1114
Query: 192 KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECS- 249
D+ D+DECA GG C++ + C C G + C+ + D+C
Sbjct: 1115 NGDNCED---DVDECASQPCQ-HGGSCIDLVARYLCSCPPGTL----GVLCEINEDDCGP 1166
Query: 250 ---ITSG--ICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNT 304
+ SG NG C + +G ++C C GY ++ + C+
Sbjct: 1167 GPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTR-DCLQD 1225
Query: 305 PGS-YHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVG-----SYTCTCTD 356
PG + C C G+ G C+ + C ++PC GGQCR + G ++TC C
Sbjct: 1226 PGGGFRCLCHAGF----SGPRCQTVLSPCE--SQPCQHGGQCRPSPGPGGGLTFTCHCAQ 1279
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
P C+ + + + + + + P SC + GS
Sbjct: 1280 PFWG------PRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGS--- 1330
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
P G S C L C PA L F+C C GW G
Sbjct: 1331 --PPGASNASCAAAPC-------LHGGSCRPAP----LAPFFRCACAQGWTGPRCEAPAA 1377
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
++ C PRA C G RC + G G+
Sbjct: 1378 APEVSEEPRC-PRAACQAKRGDQRCDRECNSPGCGW 1412
Score = 78.2 bits (184), Expect = 7e-14
Identities = 73/225 (32%), Positives = 91/225 (40%), Gaps = 35/225 (15%)
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGS 406
G+ C DG P A G + T E A L V E + DP C G G
Sbjct: 37 GAAAPPCLDGS-PCANGGRCTQLPSREAACLCPP---GWVGERCQLEDPCHSGPCAGRGV 92
Query: 407 CHNTI----GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
C +++ F C+CP G+ +GP C+ D C C H A + G F C C
Sbjct: 93 CQSSVVAGTARFSCRCPRGF-----RGPDCSLPDPCLSSPC-AHGARCSVGPDGRFLCSC 146
Query: 463 RDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G++G DVDEC C TC NT GSFRC C GY G C
Sbjct: 147 PPGYQGRSCR-SDVDECRVGEP-CRHGGTCLNTPGSFRCQCPAGYTGP-------LCENP 197
Query: 523 CVDIDECANDPTLCENGHCSNTPGG--YECDCDVGFTRAADGRSC 565
V CA P+ C NG G Y+C C GF +G++C
Sbjct: 198 AV---PCA--PSPCRNGGTCRQSGDLTYDCACLPGF----EGQNC 233
>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
Length = 2281
Score = 174 bits (424), Expect = 6e-43
Identities = 140/461 (30%), Positives = 199/461 (43%), Gaps = 75/461 (16%)
Query: 127 GLC-GHGRCRN-LLGG---FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CH-NT 179
G C G G C++ ++ G F+C C G+ + C + C + C G C
Sbjct: 45 GPCAGRGVCQSSVVAGTARFSCRCPRGF----RGPDCSLPDPC--LSSPCAHGARCSVGP 98
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDR 239
+G F C C PGY+ D+DEC + GG C+NT GSFRC+C G P
Sbjct: 99 DGRFLCSCPPGYQGRSCRS---DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY-TGP-- 152
Query: 240 LSCKDIDECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
C++ C NG Q G TY C C G+ + + RC
Sbjct: 153 -LCEN-PAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVN-----VDDCPGHRC 205
Query: 298 QH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGSYTCT 353
+ +CV+ +Y+C C W G+ C D+DEC C GG C NT+G ++C
Sbjct: 206 LNGGTCVDGVNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCV 261
Query: 354 CTDGLVPSAAG------AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
C +G + A C C D +++ + + + + + C + C
Sbjct: 262 CVNGWTGESCSQNIDDCATAVCFHGATCHDRVAS-FYCACPMGKTGLLCHLDDACVSNPC 320
Query: 408 H-------NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSF 458
H N + G +C CP G++ G AC D DEC +G C C+N GSF
Sbjct: 321 HEDAICDTNPVNGRAICTCPPGFT-----GGACDQDVDECSIGANPCEHLGRCVNTQGSF 375
Query: 459 QCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C+C G+ G CE DV+ECL +G C +ATC + G F C+C G+ G
Sbjct: 376 LCQCGRGY--TGPRCETDVNECL--SGPCRNQATCLDRIGQFTCICMAGFTG-------- 423
Query: 518 CCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
Y VDIDEC + P C NG C + G+ C C GF+
Sbjct: 424 --TYCEVDIDECQSSP--CVNGGVCKDRVNGFSCTCPSGFS 460
Score = 165 bits (400), Expect = 5e-40
Identities = 147/482 (30%), Positives = 208/482 (43%), Gaps = 90/482 (18%)
Query: 116 QMEVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
Q +V+ECA P CG HG C NL G F+C C GY S + D+N+C+ + G G
Sbjct: 768 QQDVDECAG-PAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ---DINDCDPNPCLNG-G 822
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + GSF+C C PG+ ++ D+DEC N C G C + SF C C G
Sbjct: 823 SCQDGVGSFSCSCLPGFAGPRCAR---DVDECLSNP--CGPGTCTDHVASFTCTCPPGY- 876
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
C+ D+ +CS +S C NG C + + ++ C+C GY + +
Sbjct: 877 ---GGFHCEQDLPDCSPSS--CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRP- 930
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPC-GGGQCRNTVG 348
C H C + CTC E + G C+ +D C+ +PC GG+C T G
Sbjct: 931 ----CLHGGVCSAAHPGFRCTCLESF----TGPQCQTLVDWCS--RQPCQNGGRCVQT-G 979
Query: 349 SYTCTCTDGL---------VPSAAGA-------KPTCQDIDECADLISTIIMMSVD---- 388
+Y C C G +P A + CQ +C D S+ + +
Sbjct: 980 AY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTG 1038
Query: 389 -ELQKSVDPQIPELCG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
++ VDP + + C G+C +G ++C+C GY+ G C DD DEC + C
Sbjct: 1039 SHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYN-----GDNCEDDVDEC--ASQPC 1091
Query: 446 HPAADCINLPGSFQCRCRDGWRGDGATCE-DVDEC-----LTNNGGCHPRATCANTDGSF 499
CI+L + C C G G CE + D+C L + C TC + G F
Sbjct: 1092 QHGGSCIDLVARYLCSCPPGTLG--VLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGF 1149
Query: 500 RCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH---CSNTP-GGYECDCDVG 555
RC C GY GLR C DI+EC + C H C P GG+ C C G
Sbjct: 1150 RCTCPPGYT----GLR---CE---ADINECRSG--ACHAAHTRDCLQDPGGGFRCLCHAG 1197
Query: 556 FT 557
F+
Sbjct: 1198 FS 1199
Score = 158 bits (383), Expect = 6e-38
Identities = 134/450 (29%), Positives = 187/450 (41%), Gaps = 81/450 (18%)
Query: 118 EVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC C HG C N G F C C GY + V +G G C
Sbjct: 118 DVDECRVGEP-CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNG----GTC 172
Query: 177 HNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+ + ++ C C PG++ + V++D+C + L GG CV+ ++ C+C
Sbjct: 173 RQSGDLTYDCACLPGFEGQNCE---VNVDDCPGHRCL-NGGTCVDGVNTYNCQCPPEW-- 226
Query: 236 APDRLSCKDIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ +D+DEC + C N G C N +G + CVC G+ + +
Sbjct: 227 -TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAV--- 282
Query: 295 XRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT---VGS 349
C H +C + S++C C G G C D C + PC +T G
Sbjct: 283 --CFHGATCHDRVASFYCACPMG----KTGLLCHLDDACV--SNPCHEDAICDTNPVNGR 334
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
CTC G A QD+DEC +I + L G C N
Sbjct: 335 AICTCPPGFTGGACD-----QDVDEC-----SIGANPCEHL--------------GRCVN 370
Query: 410 TIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG 468
T GSF+CQC GY+ GP C TD +EC G C A C++ G F C C G+
Sbjct: 371 TQGSFLCQCGRGYT-----GPRCETDVNECLSG--PCRNQATCLDRIGQFTCICMAGF-- 421
Query: 469 DGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
G CE D+DEC + C C + F C C +G+ G + C +D+D
Sbjct: 422 TGTYCEVDIDEC--QSSPCVNGGVCKDRVNGFSCTCPSGFSG------STC----QLDVD 469
Query: 528 ECANDPTLCENG-HCSNTPGGYECDCDVGF 556
ECA+ P C NG C + P GYEC C GF
Sbjct: 470 ECASTP--CRNGAKCVDQPDGYECRCAEGF 497
Score = 157 bits (382), Expect = 7e-38
Identities = 129/462 (27%), Positives = 188/462 (40%), Gaps = 68/462 (14%)
Query: 116 QMEVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC + P C C + +G FTC C G+ + + VD++EC+ V G G
Sbjct: 389 ETDVNECLSGP--CRNQATCLDRIGQFTCICMAGF---TGTYCEVDIDECQSSPCVNG-G 442
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRCECGHGM 233
C + F+C C G+ S +D+DECA CR G +CV+ + C C G
Sbjct: 443 VCKDRVNGFSCTCPSGFSG---STCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGF 497
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
E L +++D+CS C +G C + + ++ C C GY + +S
Sbjct: 498 E---GTLCDRNVDDCSPDP--CHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQP-- 550
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSY 350
C+H C++ Y C C G G +C +ID+CA + PC G CR+ + Y
Sbjct: 551 ---CRHGGKCLDLVDKYLCRCPSG----TTGVNCEVNIDDCA--SNPCTFGVCRDGINRY 601
Query: 351 TCTCTDGLVPSAAG------AKPTCQDIDECADLISTIIMM----SVDEL-QKSVDPQIP 399
C C G A C + C D + + S+ L P
Sbjct: 602 DCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAH 661
Query: 400 ELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD---DECELGTCDCHPAADCINLPG 456
E C G C++ G F C C G+S GP C+ D CE + C C +
Sbjct: 662 EPCSHGICYDAPGGFRCVCEPGWS-----GPRCSQSLARDACE--SQPCRAGGTCSSDGM 714
Query: 457 SFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFR-CLCDTGYKGDGYGLR 515
F C C G +G CE + C N C C + G C C G++G
Sbjct: 715 GFHCTCPPGVQG--RQCELLSPCTPNP--CEHGGRCESAPGQLPVCSCPQGWQGPR---- 766
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
C D+DECA +G C+N G + C C G+T
Sbjct: 767 ---CQQ---DVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT 802
Score = 153 bits (371), Expect = 2e-36
Identities = 129/460 (28%), Positives = 186/460 (40%), Gaps = 67/460 (14%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
Q++V+ECA+ P C +G +C + G+ C C G+E T D N + C G
Sbjct: 465 QLDVDECASTP--CRNGAKCVDQPDGYECRCAEGFEG-----TLCDRNVDDCSPDPCHHG 517
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGM 233
C + SF+C C PGY ++ +DEC CR GG+C++ + C C G
Sbjct: 518 RCVDGIASFSCACAPGYTG---TRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSGT 572
Query: 234 ELAPDRLSCK-DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
++C+ +ID+C+ S C+ G C + + Y CVC G+
Sbjct: 573 T----GVNCEVNIDDCA--SNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPC 626
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
SCV+ + C C G CA PC G C + G + C
Sbjct: 627 GEGG---SCVDGENGFRCLCPPG---SLPPLCLPPSHPCAH--EPCSHGICYDAPGGFRC 678
Query: 353 TCTDG---------LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQ----KSVDPQIP 399
C G L A ++P C+ C+ +Q + + P P
Sbjct: 679 VCEPGWSGPRCSQSLARDACESQP-CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTP 737
Query: 400 ELCG-AGSCHNTIGSF-VCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPG 456
C G C + G VC CP G+ QGP C D DEC G C P C NL G
Sbjct: 738 NPCEHGGRCESAPGQLPVCSCPQGW-----QGPRCQQDVDECA-GPAPCGPHGICTNLAG 791
Query: 457 SFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
SF C C G+ G +D+++C N C +C + GSF C C G+ G
Sbjct: 792 SFSCTCHGGYTGPSCD-QDINDCDPN--PCLNGGSCQDGVGSFSCSCLPGFAGPR----- 843
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
C D+DEC ++P C G C++ + C C G+
Sbjct: 844 --CAR---DVDECLSNP--CGPGTCTDHVASFTCTCPPGY 876
Score = 144 bits (350), Expect = 6e-34
Identities = 126/459 (27%), Positives = 193/459 (42%), Gaps = 68/459 (14%)
Query: 119 VNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEK--DSKNHTCVDVNECEIVDGVCGDGD 175
+++CA +C HG C + + F C C G + CV N C D +C D
Sbjct: 275 IDDCAT--AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVS-NPCH-EDAIC---D 327
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGME 234
+ G C C PG+ + D+DEC+ C GRCVNT GSF C+CG G
Sbjct: 328 TNPVNGRAICTCPPGFTGGACDQ---DVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY- 383
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
P C+ D++EC SG C N A C +++G + C+C G+ + +
Sbjct: 384 TGP---RCETDVNEC--LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPC 438
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C + + CTC G+ G +C+ D+DECA + PC G +C + Y
Sbjct: 439 VNGGV---CKDRVNGFSCTCPSGF----SGSTCQLDVDECA--STPCRNGAKCVDQPDGY 489
Query: 351 TCTCTDGLVPSAA-----GAKPTCQDIDECADLISTIIMMSV-----DELQKSVDPQIPE 400
C C +G + P C D I++ + VD +
Sbjct: 490 ECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQ 549
Query: 401 LC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSF 458
C G C + + ++C+CP G + G C + D+C C D IN +
Sbjct: 550 PCRHGGKCLDLVDKYLCRCPSGTT-----GVNCEVNIDDCASNPCTFGVCRDGIN---RY 601
Query: 459 QCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C C+ G+ G E ++EC ++ C +C + + FRCLC G L +C
Sbjct: 602 DCVCQPGFTGPLCNVE-INECASS--PCGEGGSCVDGENGFRCLCPPG------SLPPLC 652
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
S CA++P C +G C + PGG+ C C+ G++
Sbjct: 653 LPPS----HPCAHEP--CSHGICYDAPGGFRCVCEPGWS 685
Score = 139 bits (337), Expect = 2e-32
Identities = 135/471 (28%), Positives = 196/471 (41%), Gaps = 69/471 (14%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++N+C P L G G C++ +G F+C C PG+ + DV+EC + CG G C
Sbjct: 809 DINDCDPNPCLNG-GSCQDGVGSFSCSCLPGF---AGPRCARDVDEC--LSNPCGPGTCT 862
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
+ SFTC C PGY + D+ +C+ + GG CV+ SF C C G A
Sbjct: 863 DHVASFTCTCPPGYGGFHCEQ---DLPDCSPSSCF-NGGTCVDGVNSFSCLCRPGYTGA- 917
Query: 238 DRLSCK-DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
C+ + D C ++ G C ++C C E + ++
Sbjct: 918 ---HCQHEADPC-LSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQT-----LVDWCSRQP 968
Query: 297 CQHS--CVNTPGSYHCTCREGWHLR-ADGRS--CRDIDECAGGA--RPC-GGGQCRNTVG 348
CQ+ CV T G+Y C C GW R D RS CR+ G + C GGQC +
Sbjct: 969 CQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDS 1026
Query: 349 SYTCTCTDGLVPSAAG-------AKPTCQDIDECADLISTIIMMSV-----DELQKSVDP 396
S+ C C +G S A+P CQ C + + + D + VD
Sbjct: 1027 SHYCVCPEGRTGSHCEQEVDPCLAQP-CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDE 1085
Query: 397 QIPELCG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACT-DDDECELGT-CDCHPAA---- 449
+ C GSC + + ++C CP G G C ++D+C G D P
Sbjct: 1086 CASQPCQHGGSCIDLVARYLCSCPPG-----TLGVLCEINEDDCGPGPPLDSGPRCLHNG 1140
Query: 450 DCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRAT--CA-NTDGSFRCLCDT 505
C++L G F+C C G+ G CE D++EC +G CH T C + G FRCLC
Sbjct: 1141 TCVDLVGGFRCTCPPGYTG--LRCEADINEC--RSGACHAAHTRDCLQDPGGGFRCLCHA 1196
Query: 506 GYKGDG-YGLRTVCCVYSCVDIDECANDP----TLCENGHCSNTPGGYECD 551
G+ G + + C C +C P L HC+ G C+
Sbjct: 1197 GFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1247
Score = 133 bits (322), Expect = 1e-30
Identities = 132/476 (27%), Positives = 181/476 (38%), Gaps = 78/476 (16%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC + P CG G C + + FTC C PGY H D+ +C G G C
Sbjct: 847 DVDECLSNP--CGPGTCTDHVASFTCTCPPGY---GGFHCEQDLPDCSPSSCFNG-GTCV 900
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
+ SF+C CRPGY + D C L GG C FRC C P
Sbjct: 901 DGVNSFSCLCRPGYTGAHCQH---EADPCLSRPCL-HGGVCSAAHPGFRCTCLESFT-GP 955
Query: 238 DRLSCKD-IDECSITSGICSNGACENQMGTYQCVCDEGYAQS-----TVKSHXXXXXXXX 291
C+ +D CS C NG Q G Y C+C G++ ++
Sbjct: 956 Q---CQTLVDWCSRQP--CQNGGRCVQTGAY-CLCPPGWSGRLCDIRSLPCREAAAQIGV 1009
Query: 292 XXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVG 348
CQ CV+ S++C C EG R +++D C A+PC GG CR +G
Sbjct: 1010 RLEQLCQAGGQCVDEDSSHYCVCPEG---RTGSHCEQEVDPCL--AQPCQHGGTCRGYMG 1064
Query: 349 SYTCTCTDGLVPSAAG------AKPTCQDIDECADLISTI----------IMMSVDELQK 392
Y C C G A CQ C DL++ ++ ++E
Sbjct: 1065 GYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDC 1124
Query: 393 SVDPQI---PELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
P + P G+C + +G F C CP GY+ G C D +EC G C
Sbjct: 1125 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT-----GLRCEADINECRSGACHAAHT 1179
Query: 449 ADCINLPGS-FQCRCRDGWRGDGATCEDV-DECLTNNGGCHPRATCANTDG-----SFRC 501
DC+ PG F+C C G+ G C+ V C + C C + G +F C
Sbjct: 1180 RDCLQDPGGGFRCLCHAGF--SGPRCQTVLSPC--ESQPCQHGGQCRPSPGPGGGLTFTC 1235
Query: 502 LCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
C + +G R SC ++ P C TP G C C G +
Sbjct: 1236 HCAQPF----WGPRCERVARSCRELQCPVGVP-------CQQTPRGPRCACPPGLS 1280
Score = 86.6 bits (205), Expect = 2e-16
Identities = 78/266 (29%), Positives = 114/266 (42%), Gaps = 51/266 (19%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ EV+ C A P C HG CR +GG+ C+C PGY D+ DV+EC G G
Sbjct: 1042 EQEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGYNGDNCED---DVDECASQPCQHG-G 1095
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKIC-VDIDECA-----DNDALC-RGGRCVNTAGSFRC 227
C + + C C PG +C ++ D+C D+ C G CV+ G FRC
Sbjct: 1096 SCIDLVARYLCSCPPG----TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRC 1151
Query: 228 ECGHGMELAPDRLSCK-DIDECSITSGIC----SNGACENQMGTYQCVCDEGYAQSTVKS 282
C G L C+ DI+EC SG C + ++ G ++C+C G++ ++
Sbjct: 1152 TCPPGY----TGLRCEADINEC--RSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQT 1205
Query: 283 HXXXXXXXXXXXXRCQH--SCVNTPG-----SYHCTCREG-WHLRAD--GRSCRDIDECA 332
CQH C +PG ++ C C + W R + RSCR++ +C
Sbjct: 1206 -----VLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCREL-QCP 1259
Query: 333 GGARPCGGGQCRNTVGSYTCTCTDGL 358
G C+ T C C GL
Sbjct: 1260 VGV------PCQQTPRGPRCACPPGL 1279
Score = 80.2 bits (189), Expect = 2e-14
Identities = 93/396 (23%), Positives = 141/396 (35%), Gaps = 57/396 (14%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGY 191
G+C + C C G + +H +V+ C + G C G + C C PGY
Sbjct: 1019 GQCVDEDSSHYCVCPEGR---TGSHCEQEVDPC-LAQPCQHGGTCRGYMGGYMCECLPGY 1074
Query: 192 KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECS- 249
D+ D+DECA GG C++ + C C G + C+ + D+C
Sbjct: 1075 NGDNCED---DVDECASQPCQ-HGGSCIDLVARYLCSCPPGTL----GVLCEINEDDCGP 1126
Query: 250 ---ITSG--ICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNT 304
+ SG NG C + +G ++C C GY ++ + C+
Sbjct: 1127 GPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTR-DCLQD 1185
Query: 305 PGS-YHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVG-----SYTCTCTD 356
PG + C C G+ G C+ + C ++PC GGQCR + G ++TC C
Sbjct: 1186 PGGGFRCLCHAGF----SGPRCQTVLSPCE--SQPCQHGGQCRPSPGPGGGLTFTCHCAQ 1239
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
P C+ + + + + + + P SC + GS
Sbjct: 1240 PFWG------PRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGS--- 1290
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
P G S C L C PA L F+C C GW G
Sbjct: 1291 --PPGASNASCAAAPC-------LHGGSCRPAP----LAPFFRCACAQGWTGPRCEAPAA 1337
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
++ C PRA C G RC + G G+
Sbjct: 1338 APEVSEEPRC-PRAACQAKRGDQRCDRECNSPGCGW 1372
Score = 77.8 bits (183), Expect = 1e-13
Identities = 57/169 (33%), Positives = 72/169 (42%), Gaps = 30/169 (17%)
Query: 403 GAGSCHNTI----GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
G G C +++ F C+CP G+ +GP C+ D C C H A + G F
Sbjct: 49 GRGVCQSSVVAGTARFSCRCPRGF-----RGPDCSLPDPCLSSPC-AHGARCSVGPDGRF 102
Query: 459 QCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C C G++G DVDEC C TC NT GSFRC C GY G
Sbjct: 103 LCSCPPGYQGRSCR-SDVDECRVGEP-CRHGGTCLNTPGSFRCQCPAGYTGP-------L 153
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGG--YECDCDVGFTRAADGRSC 565
C V CA P+ C NG G Y+C C GF +G++C
Sbjct: 154 CENPAV---PCA--PSPCRNGGTCRQSGDLTYDCACLPGF----EGQNC 193
Score = 72.1 bits (169), Expect = 5e-12
Identities = 49/146 (33%), Positives = 61/146 (41%), Gaps = 24/146 (16%)
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGS--FQCRCRDGWRGDGATC 473
C CP G+ G C +D C G C + G+ F CRC G+RG C
Sbjct: 25 CLCPPGWV-----GERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPD--C 77
Query: 474 EDVDECLTNNGGCHPRATCA-NTDGSFRCLCDTGYKGDGYGLRTVCCVYSC-VDIDECAN 531
D CL++ C A C+ DG F C C GY+G SC D+DEC
Sbjct: 78 SLPDPCLSSP--CAHGARCSVGPDGRFLCSCPPGYQGR-----------SCRSDVDECRV 124
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFT 557
G C NTPG + C C G+T
Sbjct: 125 GEPCRHGGTCLNTPGSFRCQCPAGYT 150
>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
protein.
Length = 1289
Score = 174 bits (424), Expect = 6e-43
Identities = 140/461 (30%), Positives = 199/461 (43%), Gaps = 75/461 (16%)
Query: 127 GLC-GHGRCRN-LLGG---FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CH-NT 179
G C G G C++ ++ G F+C C G+ + C + C + C G C
Sbjct: 88 GPCAGRGVCQSSVVAGTARFSCRCPRGF----RGPDCSLPDPC--LSSPCAHGARCSVGP 141
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDR 239
+G F C C PGY+ D+DEC + GG C+NT GSFRC+C G P
Sbjct: 142 DGRFLCSCPPGYQGRSCRS---DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY-TGP-- 195
Query: 240 LSCKDIDECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
C++ C NG Q G TY C C G+ + + RC
Sbjct: 196 -LCEN-PAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVN-----VDDCPGHRC 248
Query: 298 QH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGSYTCT 353
+ +CV+ +Y+C C W G+ C D+DEC C GG C NT+G ++C
Sbjct: 249 LNGGTCVDGVNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCV 304
Query: 354 CTDGLVPSAAG------AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
C +G + A C C D +++ + + + + + C + C
Sbjct: 305 CVNGWTGESCSQNIDDCATAVCFHGATCHDRVAS-FYCACPMGKTGLLCHLDDACVSNPC 363
Query: 408 H-------NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSF 458
H N + G +C CP G++ G AC D DEC +G C C+N GSF
Sbjct: 364 HEDAICDTNPVNGRAICTCPPGFT-----GGACDQDVDECSIGANPCEHLGRCVNTQGSF 418
Query: 459 QCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C+C G+ G CE DV+ECL +G C +ATC + G F C+C G+ G
Sbjct: 419 LCQCGRGY--TGPRCETDVNECL--SGPCRNQATCLDRIGQFTCICMAGFTG-------- 466
Query: 518 CCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
Y VDIDEC + P C NG C + G+ C C GF+
Sbjct: 467 --TYCEVDIDECQSSP--CVNGGVCKDRVNGFSCTCPSGFS 503
Score = 158 bits (383), Expect = 6e-38
Identities = 134/450 (29%), Positives = 187/450 (41%), Gaps = 81/450 (18%)
Query: 118 EVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC C HG C N G F C C GY + V +G G C
Sbjct: 161 DVDECRVGEP-CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNG----GTC 215
Query: 177 HNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
+ + ++ C C PG++ + V++D+C + L GG CV+ ++ C+C
Sbjct: 216 RQSGDLTYDCACLPGFEGQNCE---VNVDDCPGHRCL-NGGTCVDGVNTYNCQCPPEW-- 269
Query: 236 APDRLSCKDIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ +D+DEC + C N G C N +G + CVC G+ + +
Sbjct: 270 -TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAV--- 325
Query: 295 XRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT---VGS 349
C H +C + S++C C G G C D C + PC +T G
Sbjct: 326 --CFHGATCHDRVASFYCACPMG----KTGLLCHLDDACV--SNPCHEDAICDTNPVNGR 377
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
CTC G A QD+DEC +I + L G C N
Sbjct: 378 AICTCPPGFTGGACD-----QDVDEC-----SIGANPCEHL--------------GRCVN 413
Query: 410 TIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG 468
T GSF+CQC GY+ GP C TD +EC G C A C++ G F C C G+
Sbjct: 414 TQGSFLCQCGRGYT-----GPRCETDVNECLSG--PCRNQATCLDRIGQFTCICMAGF-- 464
Query: 469 DGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
G CE D+DEC + C C + F C C +G+ G + C +D+D
Sbjct: 465 TGTYCEVDIDEC--QSSPCVNGGVCKDRVNGFSCTCPSGFSG------STC----QLDVD 512
Query: 528 ECANDPTLCENG-HCSNTPGGYECDCDVGF 556
ECA+ P C NG C + P GYEC C GF
Sbjct: 513 ECASTP--CRNGAKCVDQPDGYECRCAEGF 540
Score = 148 bits (358), Expect = 6e-35
Identities = 132/457 (28%), Positives = 193/457 (42%), Gaps = 59/457 (12%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +V+EC + P C HG +C +L+ + C C G + C +VN + C G
Sbjct: 583 ESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSG----TTGVNC-EVNIDDCASNPCTFG 635
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C+PG+ +C V+I+ECA + GG CV+ FRC C G
Sbjct: 636 VCRDGINRYDCVCQPGFTGP----LCNVEINECASSPC-GEGGSCVDGENGFRCLCPPG- 689
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L P L C+ CS+G C + G ++CVC+ G++ S
Sbjct: 690 SLPP--LCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGWSGPRC-SQSLARDACESQ 744
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSY-T 351
R +C + +HCTC G GR C + C PC GG+C + G
Sbjct: 745 PCRAGGTCSSDGMGFHCTCPPG----VQGRQCELLSPCT--PNPCEHGGRCESAPGQLPV 798
Query: 352 CTCTDGLV-PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNT 410
C+C G P G +CQD + S + + + VD + CG G+C +
Sbjct: 799 CSCPQGWQDPCLNGG--SCQD-GVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDH 855
Query: 411 IGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
+ SF C CP GY G C + D + C C++ SF C CR G+ G
Sbjct: 856 VASFTCTCPPGYG-----GFHC-EQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY--TG 907
Query: 471 ATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC 529
A C+ + D CL+ C C+ FRC C + G +T+ +D C
Sbjct: 908 AHCQHEADPCLSR--PCLHGGVCSAAHPGFRCTCLESFTGP--QCQTL--------VDWC 955
Query: 530 ANDPTLCEN-GHCSNTPGGYECDCDVGFT-RAADGRS 564
+ P C+N G C T G Y C C G++ R D RS
Sbjct: 956 SRQP--CQNGGRCVQT-GAY-CLCPPGWSGRLCDIRS 988
Score = 144 bits (350), Expect = 6e-34
Identities = 126/459 (27%), Positives = 193/459 (42%), Gaps = 68/459 (14%)
Query: 119 VNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEK--DSKNHTCVDVNECEIVDGVCGDGD 175
+++CA +C HG C + + F C C G + CV N C D +C D
Sbjct: 318 IDDCAT--AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVS-NPCH-EDAIC---D 370
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGME 234
+ G C C PG+ + D+DEC+ C GRCVNT GSF C+CG G
Sbjct: 371 TNPVNGRAICTCPPGFTGGACDQ---DVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY- 426
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
P C+ D++EC SG C N A C +++G + C+C G+ + +
Sbjct: 427 TGP---RCETDVNEC--LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPC 481
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C + + CTC G+ G +C+ D+DECA + PC G +C + Y
Sbjct: 482 VNGGV---CKDRVNGFSCTCPSGF----SGSTCQLDVDECA--STPCRNGAKCVDQPDGY 532
Query: 351 TCTCTDGLVPSAA-----GAKPTCQDIDECADLISTIIMMSV-----DELQKSVDPQIPE 400
C C +G + P C D I++ + VD +
Sbjct: 533 ECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQ 592
Query: 401 LC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSF 458
C G C + + ++C+CP G + G C + D+C C D IN +
Sbjct: 593 PCRHGGKCLDLVDKYLCRCPSGTT-----GVNCEVNIDDCASNPCTFGVCRDGIN---RY 644
Query: 459 QCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C C+ G+ G E ++EC ++ C +C + + FRCLC G L +C
Sbjct: 645 DCVCQPGFTGPLCNVE-INECASS--PCGEGGSCVDGENGFRCLCPPG------SLPPLC 695
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
S CA++P C +G C + PGG+ C C+ G++
Sbjct: 696 LPPS----HPCAHEP--CSHGICYDAPGGFRCVCEPGWS 728
Score = 133 bits (322), Expect = 1e-30
Identities = 132/476 (27%), Positives = 181/476 (38%), Gaps = 78/476 (16%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+V+EC + P CG G C + + FTC C PGY H D+ +C G G C
Sbjct: 838 DVDECLSNP--CGPGTCTDHVASFTCTCPPGY---GGFHCEQDLPDCSPSSCFNG-GTCV 891
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
+ SF+C CRPGY + D C L GG C FRC C P
Sbjct: 892 DGVNSFSCLCRPGYTGAHCQH---EADPCLSRPCL-HGGVCSAAHPGFRCTCLESFT-GP 946
Query: 238 DRLSCKD-IDECSITSGICSNGACENQMGTYQCVCDEGYAQS-----TVKSHXXXXXXXX 291
C+ +D CS C NG Q G Y C+C G++ ++
Sbjct: 947 Q---CQTLVDWCSRQP--CQNGGRCVQTGAY-CLCPPGWSGRLCDIRSLPCREAAAQIGV 1000
Query: 292 XXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVG 348
CQ CV+ S++C C EG R +++D C A+PC GG CR +G
Sbjct: 1001 RLEQLCQAGGQCVDEDSSHYCVCPEG---RTGSHCEQEVDPCL--AQPCQHGGTCRGYMG 1055
Query: 349 SYTCTCTDGLVPSAAG------AKPTCQDIDECADLISTI----------IMMSVDELQK 392
Y C C G A CQ C DL++ ++ ++E
Sbjct: 1056 GYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDC 1115
Query: 393 SVDPQI---PELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
P + P G+C + +G F C CP GY+ G C D +EC G C
Sbjct: 1116 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT-----GLRCEADINECRSGACHAAHT 1170
Query: 449 ADCINLPGS-FQCRCRDGWRGDGATCEDV-DECLTNNGGCHPRATCANTDG-----SFRC 501
DC+ PG F+C C G+ G C+ V C + C C + G +F C
Sbjct: 1171 RDCLQDPGGGFRCLCHAGF--SGPRCQTVLSPC--ESQPCQHGGQCRPSPGPGGGLTFTC 1226
Query: 502 LCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
C + +G R SC ++ P C TP G C C G +
Sbjct: 1227 HCAQPF----WGPRCERVARSCRELQCPVGVP-------CQQTPRGPRCACPPGLS 1271
Score = 133 bits (321), Expect = 2e-30
Identities = 130/457 (28%), Positives = 188/457 (41%), Gaps = 68/457 (14%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGY 191
G C++ +G F+C C PG+ + DV+EC + CG G C + SFTC C PGY
Sbjct: 813 GSCQDGVGSFSCSCLPGF---AGPRCARDVDEC--LSNPCGPGTCTDHVASFTCTCPPGY 867
Query: 192 KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECSI 250
+ D+ +C+ + GG CV+ SF C C G A C+ + D C +
Sbjct: 868 GGFHCEQ---DLPDCSPSSCF-NGGTCVDGVNSFSCLCRPGYTGA----HCQHEADPC-L 918
Query: 251 TSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSY 308
+ G C ++C C E + ++ CQ+ CV T G+Y
Sbjct: 919 SRPCLHGGVCSAAHPGFRCTCLESFTGPQCQT-----LVDWCSRQPCQNGGRCVQT-GAY 972
Query: 309 HCTCREGWHLR-ADGRS--CRDIDECAGGA--RPC-GGGQCRNTVGSYTCTCTDGLVPSA 362
C C GW R D RS CR+ G + C GGQC + S+ C C +G S
Sbjct: 973 -CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSH 1031
Query: 363 AG-------AKPTCQDIDECADLISTIIMMSV-----DELQKSVDPQIPELCG-AGSCHN 409
A+P CQ C + + + D + VD + C GSC +
Sbjct: 1032 CEQEVDPCLAQP-CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCID 1090
Query: 410 TIGSFVCQCPDGYSVKPEQGPACT-DDDECELGT-CDCHPAA----DCINLPGSFQCRCR 463
+ ++C CP G G C ++D+C G D P C++L G F+C C
Sbjct: 1091 LVARYLCSCPPG-----TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP 1145
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRAT--CA-NTDGSFRCLCDTGYKGDG-YGLRTVC 518
G+ G CE D++EC +G CH T C + G FRCLC G+ G + + C
Sbjct: 1146 PGYTG--LRCEADINEC--RSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPC 1201
Query: 519 CVYSCVDIDECANDP----TLCENGHCSNTPGGYECD 551
C +C P L HC+ G C+
Sbjct: 1202 ESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1238
Score = 129 bits (312), Expect = 2e-29
Identities = 124/429 (28%), Positives = 177/429 (41%), Gaps = 84/429 (19%)
Query: 168 DGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC 227
D G C + GSF+C C PG+ ++ D+DEC N C G C + SF C
Sbjct: 807 DPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR---DVDECLSNP--CGPGTCTDHVASFTC 861
Query: 228 ECGHGMELAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXX 285
C G C+ D+ +CS +S C NG C + + ++ C+C GY + +
Sbjct: 862 TCPPGY----GGFHCEQDLPDCSPSS--CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEAD 915
Query: 286 XXXXXXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPC-GGG 341
C H C + CTC E + G C+ +D C+ +PC GG
Sbjct: 916 PCLSRP-----CLHGGVCSAAHPGFRCTCLESF----TGPQCQTLVDWCS--RQPCQNGG 964
Query: 342 QCRNTVGSYTCTCTDGL---------VPSAAGA-------KPTCQDIDECADLISTIIMM 385
+C T G+Y C C G +P A + CQ +C D S+ +
Sbjct: 965 RCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCV 1022
Query: 386 SVD-----ELQKSVDPQIPELCG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DEC 438
+ ++ VDP + + C G+C +G ++C+C GY+ G C DD DEC
Sbjct: 1023 CPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYN-----GDNCEDDVDEC 1077
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDEC-----LTNNGGCHPRATC 492
+ C CI+L + C C G G CE + D+C L + C TC
Sbjct: 1078 --ASQPCQHGGSCIDLVARYLCSCPPGTLG--VLCEINEDDCGPGPPLDSGPRCLHNGTC 1133
Query: 493 ANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH---CSNTP-GGY 548
+ G FRC C GY GLR C DI+EC + C H C P GG+
Sbjct: 1134 VDLVGGFRCTCPPGYT----GLR---CE---ADINECRSG--ACHAAHTRDCLQDPGGGF 1181
Query: 549 ECDCDVGFT 557
C C GF+
Sbjct: 1182 RCLCHAGFS 1190
Score = 86.6 bits (205), Expect = 2e-16
Identities = 78/266 (29%), Positives = 114/266 (42%), Gaps = 51/266 (19%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ EV+ C A P C HG CR +GG+ C+C PGY D+ DV+EC G G
Sbjct: 1033 EQEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGYNGDNCED---DVDECASQPCQHG-G 1086
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKIC-VDIDECA-----DNDALC-RGGRCVNTAGSFRC 227
C + + C C PG +C ++ D+C D+ C G CV+ G FRC
Sbjct: 1087 SCIDLVARYLCSCPPG----TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRC 1142
Query: 228 ECGHGMELAPDRLSCK-DIDECSITSGIC----SNGACENQMGTYQCVCDEGYAQSTVKS 282
C G L C+ DI+EC SG C + ++ G ++C+C G++ ++
Sbjct: 1143 TCPPGY----TGLRCEADINEC--RSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQT 1196
Query: 283 HXXXXXXXXXXXXRCQH--SCVNTPG-----SYHCTCREG-WHLRAD--GRSCRDIDECA 332
CQH C +PG ++ C C + W R + RSCR++ +C
Sbjct: 1197 -----VLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCREL-QCP 1250
Query: 333 GGARPCGGGQCRNTVGSYTCTCTDGL 358
G C+ T C C GL
Sbjct: 1251 VGV------PCQQTPRGPRCACPPGL 1270
Score = 78.2 bits (184), Expect = 7e-14
Identities = 73/225 (32%), Positives = 91/225 (40%), Gaps = 35/225 (15%)
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGS 406
G+ C DG P A G + T E A L V E + DP C G G
Sbjct: 40 GAAAPPCLDGS-PCANGGRCTQLPSREAACLCPP---GWVGERCQLEDPCHSGPCAGRGV 95
Query: 407 CHNTI----GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
C +++ F C+CP G+ +GP C+ D C C H A + G F C C
Sbjct: 96 CQSSVVAGTARFSCRCPRGF-----RGPDCSLPDPCLSSPC-AHGARCSVGPDGRFLCSC 149
Query: 463 RDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G++G DVDEC C TC NT GSFRC C GY G C
Sbjct: 150 PPGYQGRSCR-SDVDECRVGEP-CRHGGTCLNTPGSFRCQCPAGYTGP-------LCENP 200
Query: 523 CVDIDECANDPTLCENGHCSNTPGG--YECDCDVGFTRAADGRSC 565
V CA P+ C NG G Y+C C GF +G++C
Sbjct: 201 AV---PCA--PSPCRNGGTCRQSGDLTYDCACLPGF----EGQNC 236
>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
Length = 1235
Score = 171 bits (416), Expect = 6e-42
Identities = 130/456 (28%), Positives = 199/456 (43%), Gaps = 85/456 (18%)
Query: 116 QMEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+M++NEC + P C + C + +GGFTC C PG++ H +++NEC+ + +G
Sbjct: 454 EMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFK---GVHCELEINECQ-SNPCVNNG 507
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + F C C PG+ +C +DID+C+ L G +C++ + C+C G
Sbjct: 508 QCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSSTPCL-NGAKCIDHPNGYECQCATGF 562
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L ++ID C C +G C++ + +Y C+C+ GY +
Sbjct: 563 ---TGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCL 617
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTC 352
C++ Y C C+ G G +C + D+CA + PC G C + + Y+C
Sbjct: 618 N---DGRCIDLVNGYQCNCQPG----TSGVNCEINFDDCA--SNPCIHGICMDGINRYSC 668
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTI 411
C+ G DIDECA +P C G +C N +
Sbjct: 669 VCSPGFTGQRCNI-----DIDECAS-----------------NP-----CRKGATCINGV 701
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
F C CP+G P + +EC C H +C ++C C GW G
Sbjct: 702 NGFRCICPEG----PHHPSCYSQVNECLSNPC-IH--GNCTGGLSGYKCLCDAGW--VGI 752
Query: 472 TCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC-VDIDEC 529
CE D +ECL+N C TC N +RC C G+KG Y+C V+IDEC
Sbjct: 753 NCEVDKNECLSN--PCQNGGTCDNLVNGYRCTCKKGFKG-----------YNCQVNIDEC 799
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
A++P L G C + GY C C + +T G++C
Sbjct: 800 ASNPCL-NQGTCFDDISGYTCHCVLPYT----GKNC 830
Score = 170 bits (413), Expect = 1e-41
Identities = 143/497 (28%), Positives = 218/497 (43%), Gaps = 92/497 (18%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC + P L GRC +L+ G+ C+C PG + C ++N + C G C
Sbjct: 607 QIDECYSSPCL-NDGRCIDLVNGYQCNCQPG----TSGVNC-EINFDDCASNPCIHGICM 660
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELA 236
+ ++C C PG+ + +DIDECA N CR G C+N FRC C G
Sbjct: 661 DGINRYSCVCSPGFTGQ---RCNIDIDECASNP--CRKGATCINGVNGFRCICPEG---- 711
Query: 237 PDRLSC-KDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
P SC ++EC S C +G C + Y+C+CD G+ +
Sbjct: 712 PHHPSCYSQVNEC--LSNPCIHGNCTGGLSGYKCLCDAGWVGINCE-----VDKNECLSN 764
Query: 296 RCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYT 351
CQ+ +C N Y CTC++G+ G +C+ +IDECA + PC G C + + YT
Sbjct: 765 PCQNGGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECA--SNPCLNQGTCFDDISGYT 818
Query: 352 CTCT-----DGLVPSAAGAKPT-CQDIDECADLIS----TIIMMSVDELQK---SVDPQI 398
C C A P C++ C + + T + + Q+ +D I
Sbjct: 819 CHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECI 878
Query: 399 PELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPG 456
+ C G CHNT GS++C+CP G+S G C +D D+C C C++
Sbjct: 879 SKPCMNHGLCHNTQGSYMCECPPGFS-----GMDCEEDIDDCLANP--CQNGGSCMDGVN 931
Query: 457 SFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG------- 509
+F C C G+ GD D++ECL+ C TC++ S+ C C G+ G
Sbjct: 932 TFSCLCLPGFTGDKYQT-DMNECLSEP--CKNGGTCSDYVNSYTCKCQAGFDGVHCENNI 988
Query: 510 ---------------DGYGLRTVCCVYS-----CV-DIDECANDPTLCENGHCSNTPGGY 548
DG + C C+ +I+EC++ P L E G C + G Y
Sbjct: 989 NECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNE-GTCVDGLGTY 1047
Query: 549 ECDCDVGFTRAADGRSC 565
C C +G+T G++C
Sbjct: 1048 RCSCPLGYT----GKNC 1060
Score = 169 bits (412), Expect = 2e-41
Identities = 139/452 (30%), Positives = 190/452 (42%), Gaps = 69/452 (15%)
Query: 126 PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVCGDGDCHNTEGSFT 184
P C HG+C++ + +TC C PGY C D ++EC DG C + +
Sbjct: 576 PDPCHHGQCQDGIDSYTCICNPGY----MGAICSDQIDEC-YSSPCLNDGRCIDLVNGYQ 630
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD 244
C+C+PG + ++ D+CA N C G C++ + C C G R + D
Sbjct: 631 CNCQPGTSGVNCE---INFDDCASNP--CIHGICMDGINRYSCVCSPG--FTGQRCNI-D 682
Query: 245 IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH-SCV 302
IDEC+ S C GA C N + ++C+C EG + S C H +C
Sbjct: 683 IDECA--SNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----VNECLSNPCIHGNCT 735
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGL-- 358
Y C C GW G +C D +EC + PC GG C N V Y CTC G
Sbjct: 736 GGLSGYKCLCDAGW----VGINCEVDKNECL--SNPCQNGGTCDNLVNGYRCTCKKGFKG 789
Query: 359 ----VPSAAGAKPTCQDIDECADLIS-----TIIMMSVDELQKSVDPQIPELC-GAGSCH 408
V A C + C D IS ++ + Q + P P C A C
Sbjct: 790 YNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK 849
Query: 409 NT--IGSFVCQCPDGYSVKPEQGPACT-DDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
+ S+ C C G+ QG CT D DEC C H C N GS+ C C G
Sbjct: 850 ESPNFESYTCLCAPGW-----QGQRCTIDIDECISKPCMNHGL--CHNTQGSYMCECPPG 902
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+ G ED+D+CL N C +C + +F CLC G+ GD Y D
Sbjct: 903 FSGMDCE-EDIDDCLAN--PCQNGGSCMDGVNTFSCLCLPGFTGDKYQ----------TD 949
Query: 526 IDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
++EC ++P C+N G CS+ Y C C GF
Sbjct: 950 MNECLSEP--CKNGGTCSDYVNSYTCKCQAGF 979
Score = 163 bits (396), Expect = 1e-39
Identities = 133/455 (29%), Positives = 195/455 (42%), Gaps = 74/455 (16%)
Query: 135 RNLLGGFTCDCFPGYEKDSKNHTC---VDVNECEIVDGV----CGDGD-CHNTEGSFTCH 186
R L G TC +D+ TC EC+ D C +G C F+C
Sbjct: 113 RPCLNGGTCHML---SRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCK 169
Query: 187 CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDI 245
C G+ K D++EC D C+ GG C+N GS++C+C G C +
Sbjct: 170 CLTGFTGQ---KCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSL 221
Query: 246 DECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--C 301
S + G C Q G T++C C G+ ST + + RCQ+ C
Sbjct: 222 YVPCAPSPCVNGGTCR-QTGDFTFECNCLPGFEGSTCERNIDDCPNH-----RCQNGGVC 275
Query: 302 VNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLV 359
V+ +Y+C C W G+ C D+DEC C GG C N G Y C C +G
Sbjct: 276 VDGVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS 331
Query: 360 PSAAG------AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCH----- 408
A +C C D +++ M E + + + + C + CH
Sbjct: 332 GDDCSENIDDCAFASCTPGSTCIDRVASFSCMC-PEGKAGLLCHLDDACISNPCHKGALC 390
Query: 409 --NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCD-CHPAADCINLPGSFQCRCR 463
N + G ++C CP GY +G CT+D DEC + + C A C+N G+F C C
Sbjct: 391 DTNPLNGQYICTCPQGY-----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECL 445
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ G CE D++EC ++ C ATC + G F CLC G+KG V+
Sbjct: 446 KGYAGP--RCEMDINEC--HSDPCQNDATCLDKIGGFTCLCMPGFKG----------VHC 491
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
++I+EC ++P + NG C + ++C C GFT
Sbjct: 492 ELEINECQSNPCV-NNGQCVDKVNRFQCLCPPGFT 525
Score = 150 bits (363), Expect = 1e-35
Identities = 140/487 (28%), Positives = 209/487 (42%), Gaps = 87/487 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGFT--CDCFPGYEKDSKNHTCVDV--NECEIVDGVCGDGDCH 177
CA P + G G CR G FT C+C PG+E + D + C+ GVC DG
Sbjct: 225 CAPSPCVNG-GTCRQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQN-GGVCVDGV-- 279
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELA 236
NT + C C P + ++ D+DEC C+ GG C N G + C C +G +
Sbjct: 280 NT---YNCRCPPQWTGQFCTE---DVDECLLQPNACQNGGTCANRNGGYGCVCVNGW--S 331
Query: 237 PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D S ++ID+C+ S C+ G+ C +++ ++ C+C EG A
Sbjct: 332 GDDCS-ENIDDCAFAS--CTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECA-GGARPCG-GGQCRNTVGSYTC 352
C + +N G Y CTC +G+ G C D+DECA + PC G+C NT G++ C
Sbjct: 389 LCDTNPLN--GQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHC 442
Query: 353 TCTDGLVPSAAGA------KPTCQDIDECADLISTIIMMSVDELQK-SVDPQIPEL---- 401
C G CQ+ C D I + + + + +I E
Sbjct: 443 ECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNP 502
Query: 402 C-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQ 459
C G C + + F C CP G++ GP C D D+C + C A CI+ P ++
Sbjct: 503 CVNNGQCVDKVNRFQCLCPPGFT-----GPVCQIDIDDCS--STPCLNGAKCIDHPNGYE 555
Query: 460 CRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG--------D 510
C+C G+ G CE+ +D C + CH C + S+ C+C+ GY G +
Sbjct: 556 CQCATGFTG--VLCEENIDNC--DPDPCH-HGQCQDGIDSYTCICNPGYMGAICSDQIDE 610
Query: 511 GYG---LRTVCCV-----YSC------------VDIDECANDPTLCENGHCSNTPGGYEC 550
Y L C+ Y C ++ D+CA++P C +G C + Y C
Sbjct: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP--CIHGICMDGINRYSC 668
Query: 551 DCDVGFT 557
C GFT
Sbjct: 669 VCSPGFT 675
Score = 147 bits (355), Expect = 1e-34
Identities = 136/467 (29%), Positives = 200/467 (42%), Gaps = 70/467 (14%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV----DVNECEIVDGVC 171
Q+ ++ECA+ P L G C + + G+TC C Y KN V N CE VC
Sbjct: 793 QVNIDECASNPCL-NQGTCFDDISGYTCHCVLPYT--GKNCQTVLAPCSPNPCENA-AVC 848
Query: 172 GDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
+ N E S+TC C PG++ + +DIDEC + G C NT GS+ CEC
Sbjct: 849 KESP--NFE-SYTCLCAPGWQGQ---RCTIDIDECISKPCM-NHGLCHNTQGSYMCECPP 901
Query: 232 GMELAPDRLSCK-DIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
G + C+ DID+C + C NG +C + + T+ C+C G+ T +
Sbjct: 902 GFS----GMDCEEDIDDC--LANPCQNGGSCMDGVNTFSCLCLPGF---TGDKYQTDMNE 952
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPC-GGGQCRNTV 347
+ +C + SY C C+ G+ DG C + I+EC + C GG C + +
Sbjct: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGF----DGVHCENNINECTESS--CFNGGTCVDGI 1006
Query: 348 GSYTCTCTDGLVPSAA------GAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPEL 401
S++C C G S + C + C D + T + L
Sbjct: 1007 NSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNL 1066
Query: 402 CGAGSCHNTIGSFV-------CQCPDGYSVKPEQGPACTDDDECE----LGTCDCHPAAD 450
C C N G+ V C CP G++ P + D L C +
Sbjct: 1067 CSRSPCKNK-GTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGV 1125
Query: 451 CINLPGSFQCRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
CIN + C+C G+ G + CE+ +DEC +N C ATC++ G +RC C GY+G
Sbjct: 1126 CINAGNTHYCQCPLGYTG--SYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQG 1181
Query: 510 DGYGLRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVG 555
V C Y ++DEC N P C+N G C + ++C C G
Sbjct: 1182 -------VNCEY---EVDECQNQP--CQNGGTCIDLVNHFKCSCPPG 1216
Score = 139 bits (337), Expect = 2e-32
Identities = 124/465 (26%), Positives = 191/465 (41%), Gaps = 67/465 (14%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-C 176
+VNEC + P C HG C L G+ C C G+ + VD NEC + C +G C
Sbjct: 720 QVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCE---VDKNEC--LSNPCQNGGTC 772
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N + C C+ G+K + V+IDECA N L +G C + + C C L
Sbjct: 773 DNLVNGYRCTCKKGFKGYNCQ---VNIDECASNPCLNQG-TCFDDISGYTCHC----VLP 824
Query: 237 PDRLSCKDI-DECSITSGICSNGA-CENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C+ + CS C N A C+ +Y C+C G+ +
Sbjct: 825 YTGKNCQTVLAPCSPNP--CENAAVCKESPNFESYTCLCAPGW-----QGQRCTIDIDEC 877
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVG 348
C + C NT GSY C C G+ G C DID+C A PC GG C + V
Sbjct: 878 ISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEEDIDDCL--ANPCQNGGSCMDGVN 931
Query: 349 SYTCTCTDGLVPSAAGA------KPTCQDIDECADLISTII---MMSVDEL--QKSVDPQ 397
+++C C G C++ C+D +++ D + + +++
Sbjct: 932 TFSCLCLPGFTGDKYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINEC 991
Query: 398 IPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD---CIN 453
C G+C + I SF C CP G++ G C E+ C HP + C++
Sbjct: 992 TESSCFNGGTCVDGINSFSCLCPVGFT-----GSFCLH----EINECSSHPCLNEGTCVD 1042
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
G+++C C G+ G C+ + L + C + TC +CLC +G+ G
Sbjct: 1043 GLGTYRCSCPLGYTGKN--CQTLVN-LCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCD 1099
Query: 514 LRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGFT 557
+ V C + LC++ G C N + C C +G+T
Sbjct: 1100 VPNVSCDIAASRRGVLVEH--LCQHSGVCINAGNTHYCQCPLGYT 1142
Score = 135 bits (326), Expect = 5e-31
Identities = 107/398 (26%), Positives = 176/398 (44%), Gaps = 55/398 (13%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC + P + HG C N G + C+C PG+ D+++C + + G C
Sbjct: 872 IDIDECISKPCM-NHGLCHNTQGSYMCECPPGFSGMDCEE---DIDDC-LANPCQNGGSC 926
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
+ +F+C C PG+ D + D++EC ++ GG C + S+ C+C G
Sbjct: 927 MDGVNTFSCLCLPGFTGDKYQ---TDMNECL-SEPCKNGGTCSDYVNSYTCKCQAGF--- 979
Query: 237 PDRLSCKD-IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
D + C++ I+EC+ +S C NG C + + ++ C+C G+ S
Sbjct: 980 -DGVHCENNINECTESS--CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLN 1036
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCT 353
+ +CV+ G+Y C+C G+ G++C+ + + PC G C C
Sbjct: 1037 ---EGTCVDGLGTYRCSCPLGY----TGKNCQTLVNLCSRS-PCKNKGTCVQKKAESQCL 1088
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G AGA C + D+ ++ + V+ L + +G C N +
Sbjct: 1089 CPSGW----AGAY--CDVPNVSCDIAASRRGVLVEHLCQH----------SGVCINAGNT 1132
Query: 414 FVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT 472
CQCP GY+ G C + DEC C H A C + G ++C C G++G
Sbjct: 1133 HYCQCPLGYT-----GSYCEEQLDECASNPCQ-H-GATCSDFIGGYRCECVPGYQG--VN 1183
Query: 473 CE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
CE +VDEC N C TC + F+C C G +G
Sbjct: 1184 CEYEVDEC--QNQPCQNGGTCIDLVNHFKCSCPPGTRG 1219
Score = 60.5 bits (140), Expect = 2e-08
Identities = 48/168 (28%), Positives = 72/168 (42%), Gaps = 24/168 (14%)
Query: 395 DPQIPELC-GAGSC--HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
DP C G+C +G C+C G++ + Q + C + C C
Sbjct: 66 DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ---YSTSHPCFVSR-PCLNGGTC 121
Query: 452 INLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
L +++C C+ G+ G C+ D CL++ C +TC F C C TG+ G
Sbjct: 122 HMLSRDTYECTCQVGFTGK--ECQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQ 177
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
C D++EC + P C++G C N PG Y+C C GFT
Sbjct: 178 K-------CE---TDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFT 214
>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 171 bits (416), Expect = 6e-42
Identities = 130/456 (28%), Positives = 199/456 (43%), Gaps = 85/456 (18%)
Query: 116 QMEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+M++NEC + P C + C + +GGFTC C PG++ H +++NEC+ + +G
Sbjct: 454 EMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFK---GVHCELEINECQ-SNPCVNNG 507
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + F C C PG+ +C +DID+C+ L G +C++ + C+C G
Sbjct: 508 QCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSSTPCL-NGAKCIDHPNGYECQCATGF 562
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L ++ID C C +G C++ + +Y C+C+ GY +
Sbjct: 563 ---TGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCL 617
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTC 352
C++ Y C C+ G G +C + D+CA + PC G C + + Y+C
Sbjct: 618 N---DGRCIDLVNGYQCNCQPG----TSGVNCEINFDDCA--SNPCIHGICMDGINRYSC 668
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTI 411
C+ G DIDECA +P C G +C N +
Sbjct: 669 VCSPGFTGQRCNI-----DIDECAS-----------------NP-----CRKGATCINGV 701
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
F C CP+G P + +EC C H +C ++C C GW G
Sbjct: 702 NGFRCICPEG----PHHPSCYSQVNECLSNPC-IH--GNCTGGLSGYKCLCDAGW--VGI 752
Query: 472 TCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC-VDIDEC 529
CE D +ECL+N C TC N +RC C G+KG Y+C V+IDEC
Sbjct: 753 NCEVDKNECLSN--PCQNGGTCDNLVNGYRCTCKKGFKG-----------YNCQVNIDEC 799
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
A++P L G C + GY C C + +T G++C
Sbjct: 800 ASNPCL-NQGTCFDDISGYTCHCVLPYT----GKNC 830
Score = 167 bits (405), Expect = 1e-40
Identities = 139/452 (30%), Positives = 190/452 (42%), Gaps = 69/452 (15%)
Query: 126 PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVCGDGDCHNTEGSFT 184
P C HG+C++ + +TC C PGY C D ++EC DG C + +
Sbjct: 576 PDPCHHGQCQDGIDSYTCICNPGY----MGAICSDQIDEC-YSSPCLNDGRCIDLVNGYQ 630
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD 244
C+C+PG + ++ D+CA N C G C++ + C C G R + D
Sbjct: 631 CNCQPGTSGVNCE---INFDDCASNP--CIHGICMDGINRYSCVCSPG--FTGQRCNI-D 682
Query: 245 IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH-SCV 302
IDEC+ S C GA C N + ++C+C EG + S C H +C
Sbjct: 683 IDECA--SNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----VNECLSNPCIHGNCT 735
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGL-- 358
Y C C GW G +C D +EC + PC GG C N V Y CTC G
Sbjct: 736 GGLSGYKCLCDAGW----VGINCEVDKNECL--SNPCQNGGTCDNLVNGYRCTCKKGFKG 789
Query: 359 ----VPSAAGAKPTCQDIDECADLIS-----TIIMMSVDELQKSVDPQIPELC-GAGSCH 408
V A C + C D IS ++ + Q + P P C A C
Sbjct: 790 YNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK 849
Query: 409 NT--IGSFVCQCPDGYSVKPEQGPACT-DDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
+ S+ C C G+ QG CT D DEC C H C N GS+ C C G
Sbjct: 850 ESPNFESYTCLCAPGW-----QGQRCTIDIDECISKPCMNHGL--CHNTQGSYMCECPPG 902
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+ G ED+D+CL N C +C + +F CLC G+ GD C D
Sbjct: 903 FSGMDCE-EDIDDCLAN--PCQNGGSCMDGVNTFSCLCLPGFTGDK-------CQ---TD 949
Query: 526 IDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
++EC ++P C+N G CS+ Y C C GF
Sbjct: 950 MNECLSEP--CKNGGTCSDYVNSYTCKCQAGF 979
Score = 163 bits (396), Expect = 1e-39
Identities = 133/455 (29%), Positives = 195/455 (42%), Gaps = 74/455 (16%)
Query: 135 RNLLGGFTCDCFPGYEKDSKNHTC---VDVNECEIVDGV----CGDGD-CHNTEGSFTCH 186
R L G TC +D+ TC EC+ D C +G C F+C
Sbjct: 113 RPCLNGGTCHML---SRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCK 169
Query: 187 CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDI 245
C G+ K D++EC D C+ GG C+N GS++C+C G C +
Sbjct: 170 CLTGFTGQ---KCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSL 221
Query: 246 DECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--C 301
S + G C Q G T++C C G+ ST + + RCQ+ C
Sbjct: 222 YVPCAPSPCVNGGTCR-QTGDFTFECNCLPGFEGSTCERNIDDCPNH-----RCQNGGVC 275
Query: 302 VNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLV 359
V+ +Y+C C W G+ C D+DEC C GG C N G Y C C +G
Sbjct: 276 VDGVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS 331
Query: 360 PSAAG------AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCH----- 408
A +C C D +++ M E + + + + C + CH
Sbjct: 332 GDDCSENIDDCAFASCTPGSTCIDRVASFSCMC-PEGKAGLLCHLDDACISNPCHKGALC 390
Query: 409 --NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCD-CHPAADCINLPGSFQCRCR 463
N + G ++C CP GY +G CT+D DEC + + C A C+N G+F C C
Sbjct: 391 DTNPLNGQYICTCPQGY-----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECL 445
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ G CE D++EC ++ C ATC + G F CLC G+KG V+
Sbjct: 446 KGYAGP--RCEMDINEC--HSDPCQNDATCLDKIGGFTCLCMPGFKG----------VHC 491
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
++I+EC ++P + NG C + ++C C GFT
Sbjct: 492 ELEINECQSNPCV-NNGQCVDKVNRFQCLCPPGFT 525
Score = 150 bits (363), Expect = 1e-35
Identities = 140/487 (28%), Positives = 209/487 (42%), Gaps = 87/487 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGFT--CDCFPGYEKDSKNHTCVDV--NECEIVDGVCGDGDCH 177
CA P + G G CR G FT C+C PG+E + D + C+ GVC DG
Sbjct: 225 CAPSPCVNG-GTCRQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQN-GGVCVDGV-- 279
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELA 236
NT + C C P + ++ D+DEC C+ GG C N G + C C +G +
Sbjct: 280 NT---YNCRCPPQWTGQFCTE---DVDECLLQPNACQNGGTCANRNGGYGCVCVNGW--S 331
Query: 237 PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D S ++ID+C+ S C+ G+ C +++ ++ C+C EG A
Sbjct: 332 GDDCS-ENIDDCAFAS--CTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECA-GGARPCG-GGQCRNTVGSYTC 352
C + +N G Y CTC +G+ G C D+DECA + PC G+C NT G++ C
Sbjct: 389 LCDTNPLN--GQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHC 442
Query: 353 TCTDGLVPSAAGA------KPTCQDIDECADLISTIIMMSVDELQK-SVDPQIPEL---- 401
C G CQ+ C D I + + + + +I E
Sbjct: 443 ECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNP 502
Query: 402 C-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQ 459
C G C + + F C CP G++ GP C D D+C + C A CI+ P ++
Sbjct: 503 CVNNGQCVDKVNRFQCLCPPGFT-----GPVCQIDIDDCS--STPCLNGAKCIDHPNGYE 555
Query: 460 CRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG--------D 510
C+C G+ G CE+ +D C + CH C + S+ C+C+ GY G +
Sbjct: 556 CQCATGFTG--VLCEENIDNC--DPDPCH-HGQCQDGIDSYTCICNPGYMGAICSDQIDE 610
Query: 511 GYG---LRTVCCV-----YSC------------VDIDECANDPTLCENGHCSNTPGGYEC 550
Y L C+ Y C ++ D+CA++P C +G C + Y C
Sbjct: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP--CIHGICMDGINRYSC 668
Query: 551 DCDVGFT 557
C GFT
Sbjct: 669 VCSPGFT 675
Score = 145 bits (352), Expect = 3e-34
Identities = 127/467 (27%), Positives = 193/467 (41%), Gaps = 84/467 (17%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG 174
Q ++NEC + P G G C + + +TC C G++ H ++NEC + C G
Sbjct: 947 QTDMNECLSEPCKNG-GTCSDYVNSYTCKCQAGFDGV---HCENNINEC--TESSCFNGG 1000
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICV-DIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + SF+C C G+ C+ +I+EC+ + L G CV+ G++RC C G
Sbjct: 1001 TCVDGINSFSCLCPVGFTGS----FCLHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGY 1055
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQS-----TVKSHXXXXX 288
+C+ + S + G C + QC+C G+A + V
Sbjct: 1056 T----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR 1111
Query: 289 XXXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCG-GGQCR 344
CQHS C+N +++C C G+ G C + +DECA + PC G C
Sbjct: 1112 RGVLVEHLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECA--SNPCQHGATCS 1165
Query: 345 NTVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCG 403
+ +G Y C C VP G C+ ++DEC Q
Sbjct: 1166 DFIGGYRCEC----VPGYQGVN--CEYEVDEC---------------------QNQPCQN 1198
Query: 404 AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
G+C + + F C CP G +G C ++ D+C G C C++ G + CRC
Sbjct: 1199 GGTCIDLVNHFKCSCPPG-----TRGLLCEENIDDCARGP-HCLNGGQCMDRIGGYSCRC 1252
Query: 463 RDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
G+ G+ CE D++ECL+N C + C+C + + G C +
Sbjct: 1253 LPGFAGE--RCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG------RHCETF 1304
Query: 522 SCVDIDECANDPTLCENGHC---SNTPGGYECDCDVGFTRAADGRSC 565
+D C P L G C SN P G+ C C GF+ A SC
Sbjct: 1305 ----VDVCPQMPCL-NGGTCAVASNMPDGFICRCPPGFSGARCQSSC 1346
Score = 143 bits (347), Expect = 1e-33
Identities = 133/471 (28%), Positives = 196/471 (41%), Gaps = 69/471 (14%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVCGDG 174
++++ECA+ P C G C N + GF C C G S C VNEC + C G
Sbjct: 681 IDIDECASNP--CRKGATCINGVNGFRCICPEGPHHPS----CYSQVNEC--LSNPCIHG 732
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
+C + C C G+ + VD +EC N GG C N +RC C G +
Sbjct: 733 NCTGGLSGYKCLCDAGWVGINCE---VDKNECLSNPCQ-NGGTCDNLVNGYRCTCKKGFK 788
Query: 235 LAPDRLSCK-DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C+ +IDEC+ S C N G C + + Y C C Y ++
Sbjct: 789 ----GYNCQVNIDECA--SNPCLNQGTCFDDISGYTCHCVLPYTGKNCQT-----VLAPC 837
Query: 293 XXXRCQHS--CVNTPG--SYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNT 346
C+++ C +P SY C C GW G+ C DIDEC ++PC G C NT
Sbjct: 838 SPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECI--SKPCMNHGLCHNT 891
Query: 347 VGSYTCTCTDGLVPSAAG-------AKPTCQDIDECADLISTIIMMSV-----DELQKSV 394
GSY C C G A P CQ+ C D ++T + + D+ Q +
Sbjct: 892 QGSYMCECPPGFSGMDCEEDIDDCLANP-CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM 950
Query: 395 DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCI 452
+ + E C G+C + + S+ C+C G+ G C ++ +EC +C C+
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFD-----GVHCENNINECTESSC--FNGGTCV 1003
Query: 453 NLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG- 511
+ SF C C G+ G E ++EC ++ C TC + G++RC C GY G
Sbjct: 1004 DGINSFSCLCPVGFTGSFCLHE-INECSSHP--CLNEGTCVDGLGTYRCSCPLGYTGKNC 1060
Query: 512 YGLRTVCCVYSCVDIDEC----ANDPTLCENGHCSNTPGGYECDCDVGFTR 558
L +C C + C A LC +G CD+ +R
Sbjct: 1061 QTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR 1111
Score = 100 bits (239), Expect = 2e-20
Identities = 113/408 (27%), Positives = 170/408 (41%), Gaps = 76/408 (18%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDC 176
E+NEC++ P L G C + LG + C C GY KN + VN C C + G C
Sbjct: 1025 EINECSSHPCL-NEGTCVDGLGTYRCSCPLGYT--GKNCQTL-VNLCS--RSPCKNKGTC 1078
Query: 177 HNTEGSFTCHCRPGYKAD--DFSKICVDIDECADN---DALCR-GGRCVNTAGSFRCECG 230
+ C C G+ D + DI + LC+ G C+N + C+C
Sbjct: 1079 VQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCP 1138
Query: 231 HGMELAPDRLSCKD-IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXX 288
G + C++ +DEC+ S C +GA C + +G Y+C C GY +
Sbjct: 1139 LGYTGS----YCEEQLDECA--SNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQ 1192
Query: 289 XXXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCGGGQCRN 345
CQ+ +C++ + C+C G G C + ID+CA G GGQC +
Sbjct: 1193 NQP-----CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGPHCLNGGQCMD 1243
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDEC------ADLISTIIMMSVDEL-------- 390
+G Y+C C +P AG + C+ DI+EC ++ I ++ D L
Sbjct: 1244 RIGGYSCRC----LPGFAGER--CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT 1297
Query: 391 ----QKSVD--PQIPELCGAGSC---HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
+ VD PQ+P L G G+C N F+C+CP G+S G C + G
Sbjct: 1298 GRHCETFVDVCPQMPCLNG-GTCAVASNMPDGFICRCPPGFS-----GARC----QSSCG 1347
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPR 489
C C++ +C C R + C C + G CHP+
Sbjct: 1348 QVKCRKGEQCVHTASGPRCFCPSP-RDCESGCAS-SPC-QHGGSCHPQ 1392
Score = 60.5 bits (140), Expect = 2e-08
Identities = 48/168 (28%), Positives = 72/168 (42%), Gaps = 24/168 (14%)
Query: 395 DPQIPELC-GAGSC--HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
DP C G+C +G C+C G++ + Q + C + C C
Sbjct: 66 DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ---YSTSHPCFVSR-PCLNGGTC 121
Query: 452 INLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
L +++C C+ G+ G C+ D CL++ C +TC F C C TG+ G
Sbjct: 122 HMLSRDTYECTCQVGFTGK--ECQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQ 177
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
C D++EC + P C++G C N PG Y+C C GFT
Sbjct: 178 K-------CE---TDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFT 214
>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 171 bits (416), Expect = 6e-42
Identities = 130/456 (28%), Positives = 199/456 (43%), Gaps = 85/456 (18%)
Query: 116 QMEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+M++NEC + P C + C + +GGFTC C PG++ H +++NEC+ + +G
Sbjct: 454 EMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFK---GVHCELEINECQ-SNPCVNNG 507
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + F C C PG+ +C +DID+C+ L G +C++ + C+C G
Sbjct: 508 QCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSSTPCL-NGAKCIDHPNGYECQCATGF 562
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L ++ID C C +G C++ + +Y C+C+ GY +
Sbjct: 563 ---TGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCL 617
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTC 352
C++ Y C C+ G G +C + D+CA + PC G C + + Y+C
Sbjct: 618 N---DGRCIDLVNGYQCNCQPG----TSGVNCEINFDDCA--SNPCIHGICMDGINRYSC 668
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTI 411
C+ G DIDECA +P C G +C N +
Sbjct: 669 VCSPGFTGQRCNI-----DIDECAS-----------------NP-----CRKGATCINGV 701
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
F C CP+G P + +EC C H +C ++C C GW G
Sbjct: 702 NGFRCICPEG----PHHPSCYSQVNECLSNPC-IH--GNCTGGLSGYKCLCDAGW--VGI 752
Query: 472 TCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC-VDIDEC 529
CE D +ECL+N C TC N +RC C G+KG Y+C V+IDEC
Sbjct: 753 NCEVDKNECLSN--PCQNGGTCDNLVNGYRCTCKKGFKG-----------YNCQVNIDEC 799
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
A++P L G C + GY C C + +T G++C
Sbjct: 800 ASNPCL-NQGTCFDDISGYTCHCVLPYT----GKNC 830
Score = 167 bits (405), Expect = 1e-40
Identities = 139/452 (30%), Positives = 190/452 (42%), Gaps = 69/452 (15%)
Query: 126 PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVCGDGDCHNTEGSFT 184
P C HG+C++ + +TC C PGY C D ++EC DG C + +
Sbjct: 576 PDPCHHGQCQDGIDSYTCICNPGY----MGAICSDQIDEC-YSSPCLNDGRCIDLVNGYQ 630
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD 244
C+C+PG + ++ D+CA N C G C++ + C C G R + D
Sbjct: 631 CNCQPGTSGVNCE---INFDDCASNP--CIHGICMDGINRYSCVCSPG--FTGQRCNI-D 682
Query: 245 IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH-SCV 302
IDEC+ S C GA C N + ++C+C EG + S C H +C
Sbjct: 683 IDECA--SNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----VNECLSNPCIHGNCT 735
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGL-- 358
Y C C GW G +C D +EC + PC GG C N V Y CTC G
Sbjct: 736 GGLSGYKCLCDAGW----VGINCEVDKNECL--SNPCQNGGTCDNLVNGYRCTCKKGFKG 789
Query: 359 ----VPSAAGAKPTCQDIDECADLIS-----TIIMMSVDELQKSVDPQIPELC-GAGSCH 408
V A C + C D IS ++ + Q + P P C A C
Sbjct: 790 YNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK 849
Query: 409 NT--IGSFVCQCPDGYSVKPEQGPACT-DDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
+ S+ C C G+ QG CT D DEC C H C N GS+ C C G
Sbjct: 850 ESPNFESYTCLCAPGW-----QGQRCTIDIDECISKPCMNHGL--CHNTQGSYMCECPPG 902
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+ G ED+D+CL N C +C + +F CLC G+ GD C D
Sbjct: 903 FSGMDCE-EDIDDCLAN--PCQNGGSCMDGVNTFSCLCLPGFTGDK-------CQ---TD 949
Query: 526 IDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
++EC ++P C+N G CS+ Y C C GF
Sbjct: 950 MNECLSEP--CKNGGTCSDYVNSYTCKCQAGF 979
Score = 163 bits (396), Expect = 1e-39
Identities = 133/455 (29%), Positives = 195/455 (42%), Gaps = 74/455 (16%)
Query: 135 RNLLGGFTCDCFPGYEKDSKNHTC---VDVNECEIVDGV----CGDGD-CHNTEGSFTCH 186
R L G TC +D+ TC EC+ D C +G C F+C
Sbjct: 113 RPCLNGGTCHML---SRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCK 169
Query: 187 CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDI 245
C G+ K D++EC D C+ GG C+N GS++C+C G C +
Sbjct: 170 CLTGFTGQ---KCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSL 221
Query: 246 DECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--C 301
S + G C Q G T++C C G+ ST + + RCQ+ C
Sbjct: 222 YVPCAPSPCVNGGTCR-QTGDFTFECNCLPGFEGSTCERNIDDCPNH-----RCQNGGVC 275
Query: 302 VNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLV 359
V+ +Y+C C W G+ C D+DEC C GG C N G Y C C +G
Sbjct: 276 VDGVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS 331
Query: 360 PSAAG------AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCH----- 408
A +C C D +++ M E + + + + C + CH
Sbjct: 332 GDDCSENIDDCAFASCTPGSTCIDRVASFSCMC-PEGKAGLLCHLDDACISNPCHKGALC 390
Query: 409 --NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCD-CHPAADCINLPGSFQCRCR 463
N + G ++C CP GY +G CT+D DEC + + C A C+N G+F C C
Sbjct: 391 DTNPLNGQYICTCPQGY-----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECL 445
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ G CE D++EC ++ C ATC + G F CLC G+KG V+
Sbjct: 446 KGYAGP--RCEMDINEC--HSDPCQNDATCLDKIGGFTCLCMPGFKG----------VHC 491
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
++I+EC ++P + NG C + ++C C GFT
Sbjct: 492 ELEINECQSNPCV-NNGQCVDKVNRFQCLCPPGFT 525
Score = 150 bits (363), Expect = 1e-35
Identities = 140/487 (28%), Positives = 209/487 (42%), Gaps = 87/487 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGFT--CDCFPGYEKDSKNHTCVDV--NECEIVDGVCGDGDCH 177
CA P + G G CR G FT C+C PG+E + D + C+ GVC DG
Sbjct: 225 CAPSPCVNG-GTCRQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQN-GGVCVDGV-- 279
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELA 236
NT + C C P + ++ D+DEC C+ GG C N G + C C +G +
Sbjct: 280 NT---YNCRCPPQWTGQFCTE---DVDECLLQPNACQNGGTCANRNGGYGCVCVNGW--S 331
Query: 237 PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D S ++ID+C+ S C+ G+ C +++ ++ C+C EG A
Sbjct: 332 GDDCS-ENIDDCAFAS--CTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECA-GGARPCG-GGQCRNTVGSYTC 352
C + +N G Y CTC +G+ G C D+DECA + PC G+C NT G++ C
Sbjct: 389 LCDTNPLN--GQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHC 442
Query: 353 TCTDGLVPSAAGA------KPTCQDIDECADLISTIIMMSVDELQK-SVDPQIPEL---- 401
C G CQ+ C D I + + + + +I E
Sbjct: 443 ECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNP 502
Query: 402 C-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQ 459
C G C + + F C CP G++ GP C D D+C + C A CI+ P ++
Sbjct: 503 CVNNGQCVDKVNRFQCLCPPGFT-----GPVCQIDIDDCS--STPCLNGAKCIDHPNGYE 555
Query: 460 CRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG--------D 510
C+C G+ G CE+ +D C + CH C + S+ C+C+ GY G +
Sbjct: 556 CQCATGFTG--VLCEENIDNC--DPDPCH-HGQCQDGIDSYTCICNPGYMGAICSDQIDE 610
Query: 511 GYG---LRTVCCV-----YSC------------VDIDECANDPTLCENGHCSNTPGGYEC 550
Y L C+ Y C ++ D+CA++P C +G C + Y C
Sbjct: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP--CIHGICMDGINRYSC 668
Query: 551 DCDVGFT 557
C GFT
Sbjct: 669 VCSPGFT 675
Score = 145 bits (352), Expect = 3e-34
Identities = 127/467 (27%), Positives = 193/467 (41%), Gaps = 84/467 (17%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG 174
Q ++NEC + P G G C + + +TC C G++ H ++NEC + C G
Sbjct: 947 QTDMNECLSEPCKNG-GTCSDYVNSYTCKCQAGFDGV---HCENNINEC--TESSCFNGG 1000
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICV-DIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + SF+C C G+ C+ +I+EC+ + L G CV+ G++RC C G
Sbjct: 1001 TCVDGINSFSCLCPVGFTGS----FCLHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGY 1055
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQS-----TVKSHXXXXX 288
+C+ + S + G C + QC+C G+A + V
Sbjct: 1056 T----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR 1111
Query: 289 XXXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCG-GGQCR 344
CQHS C+N +++C C G+ G C + +DECA + PC G C
Sbjct: 1112 RGVLVEHLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECA--SNPCQHGATCS 1165
Query: 345 NTVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCG 403
+ +G Y C C VP G C+ ++DEC Q
Sbjct: 1166 DFIGGYRCEC----VPGYQGVN--CEYEVDEC---------------------QNQPCQN 1198
Query: 404 AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
G+C + + F C CP G +G C ++ D+C G C C++ G + CRC
Sbjct: 1199 GGTCIDLVNHFKCSCPPG-----TRGLLCEENIDDCARGP-HCLNGGQCMDRIGGYSCRC 1252
Query: 463 RDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
G+ G+ CE D++ECL+N C + C+C + + G C +
Sbjct: 1253 LPGFAGE--RCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG------RHCETF 1304
Query: 522 SCVDIDECANDPTLCENGHC---SNTPGGYECDCDVGFTRAADGRSC 565
+D C P L G C SN P G+ C C GF+ A SC
Sbjct: 1305 ----VDVCPQMPCL-NGGTCAVASNMPDGFICRCPPGFSGARCQSSC 1346
Score = 143 bits (347), Expect = 1e-33
Identities = 133/471 (28%), Positives = 196/471 (41%), Gaps = 69/471 (14%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVCGDG 174
++++ECA+ P C G C N + GF C C G S C VNEC + C G
Sbjct: 681 IDIDECASNP--CRKGATCINGVNGFRCICPEGPHHPS----CYSQVNEC--LSNPCIHG 732
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
+C + C C G+ + VD +EC N GG C N +RC C G +
Sbjct: 733 NCTGGLSGYKCLCDAGWVGINCE---VDKNECLSNPCQ-NGGTCDNLVNGYRCTCKKGFK 788
Query: 235 LAPDRLSCK-DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C+ +IDEC+ S C N G C + + Y C C Y ++
Sbjct: 789 ----GYNCQVNIDECA--SNPCLNQGTCFDDISGYTCHCVLPYTGKNCQT-----VLAPC 837
Query: 293 XXXRCQHS--CVNTPG--SYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNT 346
C+++ C +P SY C C GW G+ C DIDEC ++PC G C NT
Sbjct: 838 SPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECI--SKPCMNHGLCHNT 891
Query: 347 VGSYTCTCTDGLVPSAAG-------AKPTCQDIDECADLISTIIMMSV-----DELQKSV 394
GSY C C G A P CQ+ C D ++T + + D+ Q +
Sbjct: 892 QGSYMCECPPGFSGMDCEEDIDDCLANP-CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM 950
Query: 395 DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCI 452
+ + E C G+C + + S+ C+C G+ G C ++ +EC +C C+
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFD-----GVHCENNINECTESSC--FNGGTCV 1003
Query: 453 NLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG- 511
+ SF C C G+ G E ++EC ++ C TC + G++RC C GY G
Sbjct: 1004 DGINSFSCLCPVGFTGSFCLHE-INECSSHP--CLNEGTCVDGLGTYRCSCPLGYTGKNC 1060
Query: 512 YGLRTVCCVYSCVDIDEC----ANDPTLCENGHCSNTPGGYECDCDVGFTR 558
L +C C + C A LC +G CD+ +R
Sbjct: 1061 QTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR 1111
Score = 100 bits (239), Expect = 2e-20
Identities = 113/408 (27%), Positives = 170/408 (41%), Gaps = 76/408 (18%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDC 176
E+NEC++ P L G C + LG + C C GY KN + VN C C + G C
Sbjct: 1025 EINECSSHPCL-NEGTCVDGLGTYRCSCPLGYT--GKNCQTL-VNLCS--RSPCKNKGTC 1078
Query: 177 HNTEGSFTCHCRPGYKAD--DFSKICVDIDECADN---DALCR-GGRCVNTAGSFRCECG 230
+ C C G+ D + DI + LC+ G C+N + C+C
Sbjct: 1079 VQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCP 1138
Query: 231 HGMELAPDRLSCKD-IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXX 288
G + C++ +DEC+ S C +GA C + +G Y+C C GY +
Sbjct: 1139 LGYTGS----YCEEQLDECA--SNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQ 1192
Query: 289 XXXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCGGGQCRN 345
CQ+ +C++ + C+C G G C + ID+CA G GGQC +
Sbjct: 1193 NQP-----CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGPHCLNGGQCMD 1243
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDEC------ADLISTIIMMSVDEL-------- 390
+G Y+C C +P AG + C+ DI+EC ++ I ++ D L
Sbjct: 1244 RIGGYSCRC----LPGFAGER--CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT 1297
Query: 391 ----QKSVD--PQIPELCGAGSC---HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
+ VD PQ+P L G G+C N F+C+CP G+S G C + G
Sbjct: 1298 GRHCETFVDVCPQMPCLNG-GTCAVASNMPDGFICRCPPGFS-----GARC----QSSCG 1347
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPR 489
C C++ +C C R + C C + G CHP+
Sbjct: 1348 QVKCRKGEQCVHTASGPRCFCPSP-RDCESGCAS-SPC-QHGGSCHPQ 1392
Score = 60.5 bits (140), Expect = 2e-08
Identities = 48/168 (28%), Positives = 72/168 (42%), Gaps = 24/168 (14%)
Query: 395 DPQIPELC-GAGSC--HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
DP C G+C +G C+C G++ + Q + C + C C
Sbjct: 66 DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ---YSTSHPCFVSR-PCLNGGTC 121
Query: 452 INLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
L +++C C+ G+ G C+ D CL++ C +TC F C C TG+ G
Sbjct: 122 HMLSRDTYECTCQVGFTGK--ECQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQ 177
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
C D++EC + P C++G C N PG Y+C C GFT
Sbjct: 178 K-------CE---TDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFT 214
>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 171 bits (416), Expect = 6e-42
Identities = 130/456 (28%), Positives = 199/456 (43%), Gaps = 85/456 (18%)
Query: 116 QMEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+M++NEC + P C + C + +GGFTC C PG++ H +++NEC+ + +G
Sbjct: 454 EMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFK---GVHCELEINECQ-SNPCVNNG 507
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + F C C PG+ +C +DID+C+ L G +C++ + C+C G
Sbjct: 508 QCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSSTPCL-NGAKCIDHPNGYECQCATGF 562
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L ++ID C C +G C++ + +Y C+C+ GY +
Sbjct: 563 ---TGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCL 617
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTC 352
C++ Y C C+ G G +C + D+CA + PC G C + + Y+C
Sbjct: 618 N---DGRCIDLVNGYQCNCQPG----TSGVNCEINFDDCA--SNPCIHGICMDGINRYSC 668
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTI 411
C+ G DIDECA +P C G +C N +
Sbjct: 669 VCSPGFTGQRCNI-----DIDECAS-----------------NP-----CRKGATCINGV 701
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
F C CP+G P + +EC C H +C ++C C GW G
Sbjct: 702 NGFRCICPEG----PHHPSCYSQVNECLSNPC-IH--GNCTGGLSGYKCLCDAGW--VGI 752
Query: 472 TCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC-VDIDEC 529
CE D +ECL+N C TC N +RC C G+KG Y+C V+IDEC
Sbjct: 753 NCEVDKNECLSN--PCQNGGTCDNLVNGYRCTCKKGFKG-----------YNCQVNIDEC 799
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
A++P L G C + GY C C + +T G++C
Sbjct: 800 ASNPCL-NQGTCFDDISGYTCHCVLPYT----GKNC 830
Score = 167 bits (405), Expect = 1e-40
Identities = 139/452 (30%), Positives = 190/452 (42%), Gaps = 69/452 (15%)
Query: 126 PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVCGDGDCHNTEGSFT 184
P C HG+C++ + +TC C PGY C D ++EC DG C + +
Sbjct: 576 PDPCHHGQCQDGIDSYTCICNPGY----MGAICSDQIDEC-YSSPCLNDGRCIDLVNGYQ 630
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD 244
C+C+PG + ++ D+CA N C G C++ + C C G R + D
Sbjct: 631 CNCQPGTSGVNCE---INFDDCASNP--CIHGICMDGINRYSCVCSPG--FTGQRCNI-D 682
Query: 245 IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH-SCV 302
IDEC+ S C GA C N + ++C+C EG + S C H +C
Sbjct: 683 IDECA--SNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----VNECLSNPCIHGNCT 735
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGL-- 358
Y C C GW G +C D +EC + PC GG C N V Y CTC G
Sbjct: 736 GGLSGYKCLCDAGW----VGINCEVDKNECL--SNPCQNGGTCDNLVNGYRCTCKKGFKG 789
Query: 359 ----VPSAAGAKPTCQDIDECADLIS-----TIIMMSVDELQKSVDPQIPELC-GAGSCH 408
V A C + C D IS ++ + Q + P P C A C
Sbjct: 790 YNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK 849
Query: 409 NT--IGSFVCQCPDGYSVKPEQGPACT-DDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
+ S+ C C G+ QG CT D DEC C H C N GS+ C C G
Sbjct: 850 ESPNFESYTCLCAPGW-----QGQRCTIDIDECISKPCMNHGL--CHNTQGSYMCECPPG 902
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+ G ED+D+CL N C +C + +F CLC G+ GD C D
Sbjct: 903 FSGMDCE-EDIDDCLAN--PCQNGGSCMDGVNTFSCLCLPGFTGDK-------CQ---TD 949
Query: 526 IDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
++EC ++P C+N G CS+ Y C C GF
Sbjct: 950 MNECLSEP--CKNGGTCSDYVNSYTCKCQAGF 979
Score = 163 bits (396), Expect = 1e-39
Identities = 133/455 (29%), Positives = 195/455 (42%), Gaps = 74/455 (16%)
Query: 135 RNLLGGFTCDCFPGYEKDSKNHTC---VDVNECEIVDGV----CGDGD-CHNTEGSFTCH 186
R L G TC +D+ TC EC+ D C +G C F+C
Sbjct: 113 RPCLNGGTCHML---SRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCK 169
Query: 187 CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDI 245
C G+ K D++EC D C+ GG C+N GS++C+C G C +
Sbjct: 170 CLTGFTGQ---KCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSL 221
Query: 246 DECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--C 301
S + G C Q G T++C C G+ ST + + RCQ+ C
Sbjct: 222 YVPCAPSPCVNGGTCR-QTGDFTFECNCLPGFEGSTCERNIDDCPNH-----RCQNGGVC 275
Query: 302 VNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLV 359
V+ +Y+C C W G+ C D+DEC C GG C N G Y C C +G
Sbjct: 276 VDGVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS 331
Query: 360 PSAAG------AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCH----- 408
A +C C D +++ M E + + + + C + CH
Sbjct: 332 GDDCSENIDDCAFASCTPGSTCIDRVASFSCMC-PEGKAGLLCHLDDACISNPCHKGALC 390
Query: 409 --NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCD-CHPAADCINLPGSFQCRCR 463
N + G ++C CP GY +G CT+D DEC + + C A C+N G+F C C
Sbjct: 391 DTNPLNGQYICTCPQGY-----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECL 445
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ G CE D++EC ++ C ATC + G F CLC G+KG V+
Sbjct: 446 KGYAGP--RCEMDINEC--HSDPCQNDATCLDKIGGFTCLCMPGFKG----------VHC 491
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
++I+EC ++P + NG C + ++C C GFT
Sbjct: 492 ELEINECQSNPCV-NNGQCVDKVNRFQCLCPPGFT 525
Score = 150 bits (363), Expect = 1e-35
Identities = 140/487 (28%), Positives = 209/487 (42%), Gaps = 87/487 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGFT--CDCFPGYEKDSKNHTCVDV--NECEIVDGVCGDGDCH 177
CA P + G G CR G FT C+C PG+E + D + C+ GVC DG
Sbjct: 225 CAPSPCVNG-GTCRQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQN-GGVCVDGV-- 279
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELA 236
NT + C C P + ++ D+DEC C+ GG C N G + C C +G +
Sbjct: 280 NT---YNCRCPPQWTGQFCTE---DVDECLLQPNACQNGGTCANRNGGYGCVCVNGW--S 331
Query: 237 PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D S ++ID+C+ S C+ G+ C +++ ++ C+C EG A
Sbjct: 332 GDDCS-ENIDDCAFAS--CTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECA-GGARPCG-GGQCRNTVGSYTC 352
C + +N G Y CTC +G+ G C D+DECA + PC G+C NT G++ C
Sbjct: 389 LCDTNPLN--GQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHC 442
Query: 353 TCTDGLVPSAAGA------KPTCQDIDECADLISTIIMMSVDELQK-SVDPQIPEL---- 401
C G CQ+ C D I + + + + +I E
Sbjct: 443 ECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNP 502
Query: 402 C-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQ 459
C G C + + F C CP G++ GP C D D+C + C A CI+ P ++
Sbjct: 503 CVNNGQCVDKVNRFQCLCPPGFT-----GPVCQIDIDDCS--STPCLNGAKCIDHPNGYE 555
Query: 460 CRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG--------D 510
C+C G+ G CE+ +D C + CH C + S+ C+C+ GY G +
Sbjct: 556 CQCATGFTG--VLCEENIDNC--DPDPCH-HGQCQDGIDSYTCICNPGYMGAICSDQIDE 610
Query: 511 GYG---LRTVCCV-----YSC------------VDIDECANDPTLCENGHCSNTPGGYEC 550
Y L C+ Y C ++ D+CA++P C +G C + Y C
Sbjct: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP--CIHGICMDGINRYSC 668
Query: 551 DCDVGFT 557
C GFT
Sbjct: 669 VCSPGFT 675
Score = 145 bits (352), Expect = 3e-34
Identities = 127/467 (27%), Positives = 193/467 (41%), Gaps = 84/467 (17%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG 174
Q ++NEC + P G G C + + +TC C G++ H ++NEC + C G
Sbjct: 947 QTDMNECLSEPCKNG-GTCSDYVNSYTCKCQAGFDGV---HCENNINEC--TESSCFNGG 1000
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICV-DIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + SF+C C G+ C+ +I+EC+ + L G CV+ G++RC C G
Sbjct: 1001 TCVDGINSFSCLCPVGFTGS----FCLHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGY 1055
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQS-----TVKSHXXXXX 288
+C+ + S + G C + QC+C G+A + V
Sbjct: 1056 T----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR 1111
Query: 289 XXXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCG-GGQCR 344
CQHS C+N +++C C G+ G C + +DECA + PC G C
Sbjct: 1112 RGVLVEHLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECA--SNPCQHGATCS 1165
Query: 345 NTVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCG 403
+ +G Y C C VP G C+ ++DEC Q
Sbjct: 1166 DFIGGYRCEC----VPGYQGVN--CEYEVDEC---------------------QNQPCQN 1198
Query: 404 AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
G+C + + F C CP G +G C ++ D+C G C C++ G + CRC
Sbjct: 1199 GGTCIDLVNHFKCSCPPG-----TRGLLCEENIDDCARGP-HCLNGGQCMDRIGGYSCRC 1252
Query: 463 RDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
G+ G+ CE D++ECL+N C + C+C + + G C +
Sbjct: 1253 LPGFAGE--RCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG------RHCETF 1304
Query: 522 SCVDIDECANDPTLCENGHC---SNTPGGYECDCDVGFTRAADGRSC 565
+D C P L G C SN P G+ C C GF+ A SC
Sbjct: 1305 ----VDVCPQMPCL-NGGTCAVASNMPDGFICRCPPGFSGARCQSSC 1346
Score = 143 bits (347), Expect = 1e-33
Identities = 133/471 (28%), Positives = 196/471 (41%), Gaps = 69/471 (14%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVCGDG 174
++++ECA+ P C G C N + GF C C G S C VNEC + C G
Sbjct: 681 IDIDECASNP--CRKGATCINGVNGFRCICPEGPHHPS----CYSQVNEC--LSNPCIHG 732
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
+C + C C G+ + VD +EC N GG C N +RC C G +
Sbjct: 733 NCTGGLSGYKCLCDAGWVGINCE---VDKNECLSNPCQ-NGGTCDNLVNGYRCTCKKGFK 788
Query: 235 LAPDRLSCK-DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C+ +IDEC+ S C N G C + + Y C C Y ++
Sbjct: 789 ----GYNCQVNIDECA--SNPCLNQGTCFDDISGYTCHCVLPYTGKNCQT-----VLAPC 837
Query: 293 XXXRCQHS--CVNTPG--SYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNT 346
C+++ C +P SY C C GW G+ C DIDEC ++PC G C NT
Sbjct: 838 SPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECI--SKPCMNHGLCHNT 891
Query: 347 VGSYTCTCTDGLVPSAAG-------AKPTCQDIDECADLISTIIMMSV-----DELQKSV 394
GSY C C G A P CQ+ C D ++T + + D+ Q +
Sbjct: 892 QGSYMCECPPGFSGMDCEEDIDDCLANP-CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM 950
Query: 395 DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCI 452
+ + E C G+C + + S+ C+C G+ G C ++ +EC +C C+
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFD-----GVHCENNINECTESSC--FNGGTCV 1003
Query: 453 NLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG- 511
+ SF C C G+ G E ++EC ++ C TC + G++RC C GY G
Sbjct: 1004 DGINSFSCLCPVGFTGSFCLHE-INECSSHP--CLNEGTCVDGLGTYRCSCPLGYTGKNC 1060
Query: 512 YGLRTVCCVYSCVDIDEC----ANDPTLCENGHCSNTPGGYECDCDVGFTR 558
L +C C + C A LC +G CD+ +R
Sbjct: 1061 QTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR 1111
Score = 100 bits (239), Expect = 2e-20
Identities = 113/408 (27%), Positives = 170/408 (41%), Gaps = 76/408 (18%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDC 176
E+NEC++ P L G C + LG + C C GY KN + VN C C + G C
Sbjct: 1025 EINECSSHPCL-NEGTCVDGLGTYRCSCPLGYT--GKNCQTL-VNLCS--RSPCKNKGTC 1078
Query: 177 HNTEGSFTCHCRPGYKAD--DFSKICVDIDECADN---DALCR-GGRCVNTAGSFRCECG 230
+ C C G+ D + DI + LC+ G C+N + C+C
Sbjct: 1079 VQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCP 1138
Query: 231 HGMELAPDRLSCKD-IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXX 288
G + C++ +DEC+ S C +GA C + +G Y+C C GY +
Sbjct: 1139 LGYTGS----YCEEQLDECA--SNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQ 1192
Query: 289 XXXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCGGGQCRN 345
CQ+ +C++ + C+C G G C + ID+CA G GGQC +
Sbjct: 1193 NQP-----CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGPHCLNGGQCMD 1243
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDEC------ADLISTIIMMSVDEL-------- 390
+G Y+C C +P AG + C+ DI+EC ++ I ++ D L
Sbjct: 1244 RIGGYSCRC----LPGFAGER--CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT 1297
Query: 391 ----QKSVD--PQIPELCGAGSC---HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
+ VD PQ+P L G G+C N F+C+CP G+S G C + G
Sbjct: 1298 GRHCETFVDVCPQMPCLNG-GTCAVASNMPDGFICRCPPGFS-----GARC----QSSCG 1347
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPR 489
C C++ +C C R + C C + G CHP+
Sbjct: 1348 QVKCRKGEQCVHTASGPRCFCPSP-RDCESGCAS-SPC-QHGGSCHPQ 1392
Score = 60.5 bits (140), Expect = 2e-08
Identities = 48/168 (28%), Positives = 72/168 (42%), Gaps = 24/168 (14%)
Query: 395 DPQIPELC-GAGSC--HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
DP C G+C +G C+C G++ + Q + C + C C
Sbjct: 66 DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ---YSTSHPCFVSR-PCLNGGTC 121
Query: 452 INLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
L +++C C+ G+ G C+ D CL++ C +TC F C C TG+ G
Sbjct: 122 HMLSRDTYECTCQVGFTGK--ECQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQ 177
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
C D++EC + P C++G C N PG Y+C C GFT
Sbjct: 178 K-------CE---TDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFT 214
>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
Length = 2471
Score = 171 bits (416), Expect = 6e-42
Identities = 130/456 (28%), Positives = 199/456 (43%), Gaps = 85/456 (18%)
Query: 116 QMEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+M++NEC + P C + C + +GGFTC C PG++ H +++NEC+ + +G
Sbjct: 454 EMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFK---GVHCELEINECQ-SNPCVNNG 507
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + F C C PG+ +C +DID+C+ L G +C++ + C+C G
Sbjct: 508 QCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSSTPCL-NGAKCIDHPNGYECQCATGF 562
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L ++ID C C +G C++ + +Y C+C+ GY +
Sbjct: 563 ---TGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCL 617
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTC 352
C++ Y C C+ G G +C + D+CA + PC G C + + Y+C
Sbjct: 618 N---DGRCIDLVNGYQCNCQPG----TSGVNCEINFDDCA--SNPCIHGICMDGINRYSC 668
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTI 411
C+ G DIDECA +P C G +C N +
Sbjct: 669 VCSPGFTGQRCNI-----DIDECAS-----------------NP-----CRKGATCINGV 701
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
F C CP+G P + +EC C H +C ++C C GW G
Sbjct: 702 NGFRCICPEG----PHHPSCYSQVNECLSNPC-IH--GNCTGGLSGYKCLCDAGW--VGI 752
Query: 472 TCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC-VDIDEC 529
CE D +ECL+N C TC N +RC C G+KG Y+C V+IDEC
Sbjct: 753 NCEVDKNECLSN--PCQNGGTCDNLVNGYRCTCKKGFKG-----------YNCQVNIDEC 799
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
A++P L G C + GY C C + +T G++C
Sbjct: 800 ASNPCL-NQGTCFDDISGYTCHCVLPYT----GKNC 830
Score = 167 bits (405), Expect = 1e-40
Identities = 139/452 (30%), Positives = 190/452 (42%), Gaps = 69/452 (15%)
Query: 126 PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVCGDGDCHNTEGSFT 184
P C HG+C++ + +TC C PGY C D ++EC DG C + +
Sbjct: 576 PDPCHHGQCQDGIDSYTCICNPGY----MGAICSDQIDEC-YSSPCLNDGRCIDLVNGYQ 630
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD 244
C+C+PG + ++ D+CA N C G C++ + C C G R + D
Sbjct: 631 CNCQPGTSGVNCE---INFDDCASNP--CIHGICMDGINRYSCVCSPG--FTGQRCNI-D 682
Query: 245 IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH-SCV 302
IDEC+ S C GA C N + ++C+C EG + S C H +C
Sbjct: 683 IDECA--SNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----VNECLSNPCIHGNCT 735
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGL-- 358
Y C C GW G +C D +EC + PC GG C N V Y CTC G
Sbjct: 736 GGLSGYKCLCDAGW----VGINCEVDKNECL--SNPCQNGGTCDNLVNGYRCTCKKGFKG 789
Query: 359 ----VPSAAGAKPTCQDIDECADLIS-----TIIMMSVDELQKSVDPQIPELC-GAGSCH 408
V A C + C D IS ++ + Q + P P C A C
Sbjct: 790 YNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK 849
Query: 409 NT--IGSFVCQCPDGYSVKPEQGPACT-DDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
+ S+ C C G+ QG CT D DEC C H C N GS+ C C G
Sbjct: 850 ESPNFESYTCLCAPGW-----QGQRCTIDIDECISKPCMNHGL--CHNTQGSYMCECPPG 902
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+ G ED+D+CL N C +C + +F CLC G+ GD C D
Sbjct: 903 FSGMDCE-EDIDDCLAN--PCQNGGSCMDGVNTFSCLCLPGFTGDK-------CQ---TD 949
Query: 526 IDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
++EC ++P C+N G CS+ Y C C GF
Sbjct: 950 MNECLSEP--CKNGGTCSDYVNSYTCKCQAGF 979
Score = 162 bits (394), Expect = 3e-39
Identities = 133/455 (29%), Positives = 195/455 (42%), Gaps = 74/455 (16%)
Query: 135 RNLLGGFTCDCFPGYEKDSKNHTC---VDVNECEIVDGV----CGDGD-CHNTEGSFTCH 186
R L G TC +D+ TC EC+ D C +G C F+C
Sbjct: 113 RPCLNGGTCHML---SRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCK 169
Query: 187 CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDI 245
C G+ K D++EC D C+ GG C+N GS++C+C G C +
Sbjct: 170 CLTGFTGQ---KCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCLQGFT----GQYCDSL 221
Query: 246 DECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--C 301
S + G C Q G T++C C G+ ST + + RCQ+ C
Sbjct: 222 YVPCAPSPCVNGGTCR-QTGDFTFECNCLPGFEGSTCERNIDDCPNH-----RCQNGGVC 275
Query: 302 VNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLV 359
V+ +Y+C C W G+ C D+DEC C GG C N G Y C C +G
Sbjct: 276 VDGVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS 331
Query: 360 PSAAG------AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCH----- 408
A +C C D +++ M E + + + + C + CH
Sbjct: 332 GDDCSENIDDCAFASCTPGSTCIDRVASFSCMC-PEGKAGLLCHLDDACISNPCHKGALC 390
Query: 409 --NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCD-CHPAADCINLPGSFQCRCR 463
N + G ++C CP GY +G CT+D DEC + + C A C+N G+F C C
Sbjct: 391 DTNPLNGQYICTCPQGY-----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECL 445
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ G CE D++EC ++ C ATC + G F CLC G+KG V+
Sbjct: 446 KGYAGP--RCEMDINEC--HSDPCQNDATCLDKIGGFTCLCMPGFKG----------VHC 491
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
++I+EC ++P + NG C + ++C C GFT
Sbjct: 492 ELEINECQSNPCV-NNGQCVDKVNRFQCLCPPGFT 525
Score = 150 bits (363), Expect = 1e-35
Identities = 140/487 (28%), Positives = 209/487 (42%), Gaps = 87/487 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGFT--CDCFPGYEKDSKNHTCVDV--NECEIVDGVCGDGDCH 177
CA P + G G CR G FT C+C PG+E + D + C+ GVC DG
Sbjct: 225 CAPSPCVNG-GTCRQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQN-GGVCVDGV-- 279
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELA 236
NT + C C P + ++ D+DEC C+ GG C N G + C C +G +
Sbjct: 280 NT---YNCRCPPQWTGQFCTE---DVDECLLQPNACQNGGTCANRNGGYGCVCVNGW--S 331
Query: 237 PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D S ++ID+C+ S C+ G+ C +++ ++ C+C EG A
Sbjct: 332 GDDCS-ENIDDCAFAS--CTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECA-GGARPCG-GGQCRNTVGSYTC 352
C + +N G Y CTC +G+ G C D+DECA + PC G+C NT G++ C
Sbjct: 389 LCDTNPLN--GQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHC 442
Query: 353 TCTDGLVPSAAGA------KPTCQDIDECADLISTIIMMSVDELQK-SVDPQIPEL---- 401
C G CQ+ C D I + + + + +I E
Sbjct: 443 ECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNP 502
Query: 402 C-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQ 459
C G C + + F C CP G++ GP C D D+C + C A CI+ P ++
Sbjct: 503 CVNNGQCVDKVNRFQCLCPPGFT-----GPVCQIDIDDCS--STPCLNGAKCIDHPNGYE 555
Query: 460 CRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG--------D 510
C+C G+ G CE+ +D C + CH C + S+ C+C+ GY G +
Sbjct: 556 CQCATGFTG--VLCEENIDNC--DPDPCH-HGQCQDGIDSYTCICNPGYMGAICSDQIDE 610
Query: 511 GYG---LRTVCCV-----YSC------------VDIDECANDPTLCENGHCSNTPGGYEC 550
Y L C+ Y C ++ D+CA++P C +G C + Y C
Sbjct: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP--CIHGICMDGINRYSC 668
Query: 551 DCDVGFT 557
C GFT
Sbjct: 669 VCSPGFT 675
Score = 145 bits (352), Expect = 3e-34
Identities = 127/467 (27%), Positives = 193/467 (41%), Gaps = 84/467 (17%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG 174
Q ++NEC + P G G C + + +TC C G++ H ++NEC + C G
Sbjct: 947 QTDMNECLSEPCKNG-GTCSDYVNSYTCKCQAGFDGV---HCENNINEC--TESSCFNGG 1000
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICV-DIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + SF+C C G+ C+ +I+EC+ + L G CV+ G++RC C G
Sbjct: 1001 TCVDGINSFSCLCPVGFTGS----FCLHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGY 1055
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQS-----TVKSHXXXXX 288
+C+ + S + G C + QC+C G+A + V
Sbjct: 1056 T----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR 1111
Query: 289 XXXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCG-GGQCR 344
CQHS C+N +++C C G+ G C + +DECA + PC G C
Sbjct: 1112 RGVLVEHLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECA--SNPCQHGATCS 1165
Query: 345 NTVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCG 403
+ +G Y C C VP G C+ ++DEC Q
Sbjct: 1166 DFIGGYRCEC----VPGYQGVN--CEYEVDEC---------------------QNQPCQN 1198
Query: 404 AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
G+C + + F C CP G +G C ++ D+C G C C++ G + CRC
Sbjct: 1199 GGTCIDLVNHFKCSCPPG-----TRGLLCEENIDDCARGP-HCLNGGQCMDRIGGYSCRC 1252
Query: 463 RDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
G+ G+ CE D++ECL+N C + C+C + + G C +
Sbjct: 1253 LPGFAGE--RCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG------RHCETF 1304
Query: 522 SCVDIDECANDPTLCENGHC---SNTPGGYECDCDVGFTRAADGRSC 565
+D C P L G C SN P G+ C C GF+ A SC
Sbjct: 1305 ----VDVCPQMPCL-NGGTCAVASNMPDGFICRCPPGFSGARCQSSC 1346
Score = 143 bits (347), Expect = 1e-33
Identities = 133/471 (28%), Positives = 196/471 (41%), Gaps = 69/471 (14%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVCGDG 174
++++ECA+ P C G C N + GF C C G S C VNEC + C G
Sbjct: 681 IDIDECASNP--CRKGATCINGVNGFRCICPEGPHHPS----CYSQVNEC--LSNPCIHG 732
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
+C + C C G+ + VD +EC N GG C N +RC C G +
Sbjct: 733 NCTGGLSGYKCLCDAGWVGINCE---VDKNECLSNPCQ-NGGTCDNLVNGYRCTCKKGFK 788
Query: 235 LAPDRLSCK-DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C+ +IDEC+ S C N G C + + Y C C Y ++
Sbjct: 789 ----GYNCQVNIDECA--SNPCLNQGTCFDDISGYTCHCVLPYTGKNCQT-----VLAPC 837
Query: 293 XXXRCQHS--CVNTPG--SYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNT 346
C+++ C +P SY C C GW G+ C DIDEC ++PC G C NT
Sbjct: 838 SPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECI--SKPCMNHGLCHNT 891
Query: 347 VGSYTCTCTDGLVPSAAG-------AKPTCQDIDECADLISTIIMMSV-----DELQKSV 394
GSY C C G A P CQ+ C D ++T + + D+ Q +
Sbjct: 892 QGSYMCECPPGFSGMDCEEDIDDCLANP-CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM 950
Query: 395 DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCI 452
+ + E C G+C + + S+ C+C G+ G C ++ +EC +C C+
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFD-----GVHCENNINECTESSC--FNGGTCV 1003
Query: 453 NLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG- 511
+ SF C C G+ G E ++EC ++ C TC + G++RC C GY G
Sbjct: 1004 DGINSFSCLCPVGFTGSFCLHE-INECSSHP--CLNEGTCVDGLGTYRCSCPLGYTGKNC 1060
Query: 512 YGLRTVCCVYSCVDIDEC----ANDPTLCENGHCSNTPGGYECDCDVGFTR 558
L +C C + C A LC +G CD+ +R
Sbjct: 1061 QTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR 1111
Score = 100 bits (239), Expect = 2e-20
Identities = 113/408 (27%), Positives = 170/408 (41%), Gaps = 76/408 (18%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDC 176
E+NEC++ P L G C + LG + C C GY KN + VN C C + G C
Sbjct: 1025 EINECSSHPCL-NEGTCVDGLGTYRCSCPLGYT--GKNCQTL-VNLCS--RSPCKNKGTC 1078
Query: 177 HNTEGSFTCHCRPGYKAD--DFSKICVDIDECADN---DALCR-GGRCVNTAGSFRCECG 230
+ C C G+ D + DI + LC+ G C+N + C+C
Sbjct: 1079 VQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCP 1138
Query: 231 HGMELAPDRLSCKD-IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXX 288
G + C++ +DEC+ S C +GA C + +G Y+C C GY +
Sbjct: 1139 LGYTGS----YCEEQLDECA--SNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQ 1192
Query: 289 XXXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCGGGQCRN 345
CQ+ +C++ + C+C G G C + ID+CA G GGQC +
Sbjct: 1193 NQP-----CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGPHCLNGGQCMD 1243
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDEC------ADLISTIIMMSVDEL-------- 390
+G Y+C C +P AG + C+ DI+EC ++ I ++ D L
Sbjct: 1244 RIGGYSCRC----LPGFAGER--CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT 1297
Query: 391 ----QKSVD--PQIPELCGAGSC---HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
+ VD PQ+P L G G+C N F+C+CP G+S G C + G
Sbjct: 1298 GRHCETFVDVCPQMPCLNG-GTCAVASNMPDGFICRCPPGFS-----GARC----QSSCG 1347
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPR 489
C C++ +C C R + C C + G CHP+
Sbjct: 1348 QVKCRKGEQCVHTASGPRCFCPSP-RDCESGCAS-SPC-QHGGSCHPQ 1392
Score = 59.3 bits (137), Expect = 4e-08
Identities = 48/168 (28%), Positives = 72/168 (42%), Gaps = 24/168 (14%)
Query: 395 DPQIPELC-GAGSC--HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
DP C G+C +G C+C G++ + Q + C + C C
Sbjct: 66 DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ---YSTSHPCFVSR-PCLNGGTC 121
Query: 452 INLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
L +++C C+ G+ G C+ D CL++ C +TC F C C TG+ G
Sbjct: 122 HMLSRDTYECTCQVGFTGK--ECQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQ 177
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
C D++EC + P C++G C N PG Y+C C GFT
Sbjct: 178 K-------CE---TDVNEC-DIPGHCQHGGTCLNLPGSYQCQCLQGFT 214
>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
Length = 2471
Score = 171 bits (416), Expect = 6e-42
Identities = 130/456 (28%), Positives = 199/456 (43%), Gaps = 85/456 (18%)
Query: 116 QMEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+M++NEC + P C + C + +GGFTC C PG++ H +++NEC+ + +G
Sbjct: 454 EMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFK---GVHCELEINECQ-SNPCVNNG 507
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + F C C PG+ +C +DID+C+ L G +C++ + C+C G
Sbjct: 508 QCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSSTPCL-NGAKCIDHPNGYECQCATGF 562
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L ++ID C C +G C++ + +Y C+C+ GY +
Sbjct: 563 ---TGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCL 617
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTC 352
C++ Y C C+ G G +C + D+CA + PC G C + + Y+C
Sbjct: 618 N---DGRCIDLVNGYQCNCQPG----TSGVNCEINFDDCA--SNPCIHGICMDGINRYSC 668
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHNTI 411
C+ G DIDECA +P C G +C N +
Sbjct: 669 VCSPGFTGQRCNI-----DIDECAS-----------------NP-----CRKGATCINGV 701
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
F C CP+G P + +EC C H +C ++C C GW G
Sbjct: 702 NGFRCICPEG----PHHPSCYSQVNECLSNPC-IH--GNCTGGLSGYKCLCDAGW--VGI 752
Query: 472 TCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC-VDIDEC 529
CE D +ECL+N C TC N +RC C G+KG Y+C V+IDEC
Sbjct: 753 NCEVDKNECLSN--PCQNGGTCDNLVNGYRCTCKKGFKG-----------YNCQVNIDEC 799
Query: 530 ANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
A++P L G C + GY C C + +T G++C
Sbjct: 800 ASNPCL-NQGTCFDDISGYTCHCVLPYT----GKNC 830
Score = 167 bits (405), Expect = 1e-40
Identities = 139/452 (30%), Positives = 190/452 (42%), Gaps = 69/452 (15%)
Query: 126 PGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVCGDGDCHNTEGSFT 184
P C HG+C++ + +TC C PGY C D ++EC DG C + +
Sbjct: 576 PDPCHHGQCQDGIDSYTCICNPGY----MGAICSDQIDEC-YSSPCLNDGRCIDLVNGYQ 630
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD 244
C+C+PG + ++ D+CA N C G C++ + C C G R + D
Sbjct: 631 CNCQPGTSGVNCE---INFDDCASNP--CIHGICMDGINRYSCVCSPG--FTGQRCNI-D 682
Query: 245 IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH-SCV 302
IDEC+ S C GA C N + ++C+C EG + S C H +C
Sbjct: 683 IDECA--SNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----VNECLSNPCIHGNCT 735
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGL-- 358
Y C C GW G +C D +EC + PC GG C N V Y CTC G
Sbjct: 736 GGLSGYKCLCDAGW----VGINCEVDKNECL--SNPCQNGGTCDNLVNGYRCTCKKGFKG 789
Query: 359 ----VPSAAGAKPTCQDIDECADLIS-----TIIMMSVDELQKSVDPQIPELC-GAGSCH 408
V A C + C D IS ++ + Q + P P C A C
Sbjct: 790 YNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK 849
Query: 409 NT--IGSFVCQCPDGYSVKPEQGPACT-DDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
+ S+ C C G+ QG CT D DEC C H C N GS+ C C G
Sbjct: 850 ESPNFESYTCLCAPGW-----QGQRCTIDIDECISKPCMNHGL--CHNTQGSYMCECPPG 902
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+ G ED+D+CL N C +C + +F CLC G+ GD C D
Sbjct: 903 FSGMDCE-EDIDDCLAN--PCQNGGSCMDGVNTFSCLCLPGFTGDK-------CQ---TD 949
Query: 526 IDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
++EC ++P C+N G CS+ Y C C GF
Sbjct: 950 MNECLSEP--CKNGGTCSDYVNSYTCKCQAGF 979
Score = 163 bits (396), Expect = 1e-39
Identities = 133/455 (29%), Positives = 195/455 (42%), Gaps = 74/455 (16%)
Query: 135 RNLLGGFTCDCFPGYEKDSKNHTC---VDVNECEIVDGV----CGDGD-CHNTEGSFTCH 186
R L G TC +D+ TC EC+ D C +G C F+C
Sbjct: 113 RPCLNGGTCHML---SRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCK 169
Query: 187 CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDI 245
C G+ K D++EC D C+ GG C+N GS++C+C G C +
Sbjct: 170 CLTGFTGQ---KCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSL 221
Query: 246 DECSITSGICSNGACENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--C 301
S + G C Q G T++C C G+ ST + + RCQ+ C
Sbjct: 222 YVPCAPSPCVNGGTCR-QTGDFTFECNCLPGFEGSTCERNIDDCPNH-----RCQNGGVC 275
Query: 302 VNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLV 359
V+ +Y+C C W G+ C D+DEC C GG C N G Y C C +G
Sbjct: 276 VDGVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS 331
Query: 360 PSAAG------AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCH----- 408
A +C C D +++ M E + + + + C + CH
Sbjct: 332 GDDCSENIDDCAFASCTPGSTCIDRVASFSCMC-PEGKAGLLCHLDDACISNPCHKGALC 390
Query: 409 --NTI-GSFVCQCPDGYSVKPEQGPACTDD-DECELGTCD-CHPAADCINLPGSFQCRCR 463
N + G ++C CP GY +G CT+D DEC + + C A C+N G+F C C
Sbjct: 391 DTNPLNGQYICTCPQGY-----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECL 445
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ G CE D++EC ++ C ATC + G F CLC G+KG V+
Sbjct: 446 KGYAGP--RCEMDINEC--HSDPCQNDATCLDKIGGFTCLCMPGFKG----------VHC 491
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
++I+EC ++P + NG C + ++C C GFT
Sbjct: 492 ELEINECQSNPCV-NNGQCVDKVNRFQCLCPPGFT 525
Score = 150 bits (363), Expect = 1e-35
Identities = 140/487 (28%), Positives = 209/487 (42%), Gaps = 87/487 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGFT--CDCFPGYEKDSKNHTCVDV--NECEIVDGVCGDGDCH 177
CA P + G G CR G FT C+C PG+E + D + C+ GVC DG
Sbjct: 225 CAPSPCVNG-GTCRQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQN-GGVCVDGV-- 279
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELA 236
NT + C C P + ++ D+DEC C+ GG C N G + C C +G +
Sbjct: 280 NT---YNCRCPPQWTGQFCTE---DVDECLLQPNACQNGGTCANRNGGYGCVCVNGW--S 331
Query: 237 PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D S ++ID+C+ S C+ G+ C +++ ++ C+C EG A
Sbjct: 332 GDDCS-ENIDDCAFAS--CTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECA-GGARPCG-GGQCRNTVGSYTC 352
C + +N G Y CTC +G+ G C D+DECA + PC G+C NT G++ C
Sbjct: 389 LCDTNPLN--GQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHC 442
Query: 353 TCTDGLVPSAAGA------KPTCQDIDECADLISTIIMMSVDELQK-SVDPQIPEL---- 401
C G CQ+ C D I + + + + +I E
Sbjct: 443 ECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNP 502
Query: 402 C-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQ 459
C G C + + F C CP G++ GP C D D+C + C A CI+ P ++
Sbjct: 503 CVNNGQCVDKVNRFQCLCPPGFT-----GPVCQIDIDDCS--STPCLNGAKCIDHPNGYE 555
Query: 460 CRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG--------D 510
C+C G+ G CE+ +D C + CH C + S+ C+C+ GY G +
Sbjct: 556 CQCATGFTG--VLCEENIDNC--DPDPCH-HGQCQDGIDSYTCICNPGYMGAICSDQIDE 610
Query: 511 GYG---LRTVCCV-----YSC------------VDIDECANDPTLCENGHCSNTPGGYEC 550
Y L C+ Y C ++ D+CA++P C +G C + Y C
Sbjct: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP--CIHGICMDGINRYSC 668
Query: 551 DCDVGFT 557
C GFT
Sbjct: 669 VCSPGFT 675
Score = 145 bits (352), Expect = 3e-34
Identities = 127/467 (27%), Positives = 193/467 (41%), Gaps = 84/467 (17%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDG 174
Q ++NEC + P G G C + + +TC C G++ H ++NEC + C G
Sbjct: 947 QTDMNECLSEPCKNG-GTCSDYVNSYTCKCQAGFDGV---HCENNINEC--TESSCFNGG 1000
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICV-DIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + SF+C C G+ C+ +I+EC+ + L G CV+ G++RC C G
Sbjct: 1001 TCVDGINSFSCLCPVGFTGS----FCLHEINECSSHPCL-NEGTCVDGLGTYRCSCPLGY 1055
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQS-----TVKSHXXXXX 288
+C+ + S + G C + QC+C G+A + V
Sbjct: 1056 T----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR 1111
Query: 289 XXXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCG-GGQCR 344
CQHS C+N +++C C G+ G C + +DECA + PC G C
Sbjct: 1112 RGVLVEHLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECA--SNPCQHGATCS 1165
Query: 345 NTVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCG 403
+ +G Y C C VP G C+ ++DEC Q
Sbjct: 1166 DFIGGYRCEC----VPGYQGVN--CEYEVDEC---------------------QNQPCQN 1198
Query: 404 AGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
G+C + + F C CP G +G C ++ D+C G C C++ G + CRC
Sbjct: 1199 GGTCIDLVNHFKCSCPPG-----TRGLLCEENIDDCARGP-HCLNGGQCMDRIGGYSCRC 1252
Query: 463 RDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
G+ G+ CE D++ECL+N C + C+C + + G C +
Sbjct: 1253 LPGFAGE--RCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG------RHCETF 1304
Query: 522 SCVDIDECANDPTLCENGHC---SNTPGGYECDCDVGFTRAADGRSC 565
+D C P L G C SN P G+ C C GF+ A SC
Sbjct: 1305 ----VDVCPQMPCL-NGGTCAVASNMPDGFICRCPPGFSGARCQSSC 1346
Score = 143 bits (347), Expect = 1e-33
Identities = 133/471 (28%), Positives = 196/471 (41%), Gaps = 69/471 (14%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVCGDG 174
++++ECA+ P C G C N + GF C C G S C VNEC + C G
Sbjct: 681 IDIDECASNP--CRKGATCINGVNGFRCICPEGPHHPS----CYSQVNEC--LSNPCIHG 732
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
+C + C C G+ + VD +EC N GG C N +RC C G +
Sbjct: 733 NCTGGLSGYKCLCDAGWVGINCE---VDKNECLSNPCQ-NGGTCDNLVNGYRCTCKKGFK 788
Query: 235 LAPDRLSCK-DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C+ +IDEC+ S C N G C + + Y C C Y ++
Sbjct: 789 ----GYNCQVNIDECA--SNPCLNQGTCFDDISGYTCHCVLPYTGKNCQT-----VLAPC 837
Query: 293 XXXRCQHS--CVNTPG--SYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNT 346
C+++ C +P SY C C GW G+ C DIDEC ++PC G C NT
Sbjct: 838 SPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECI--SKPCMNHGLCHNT 891
Query: 347 VGSYTCTCTDGLVPSAAG-------AKPTCQDIDECADLISTIIMMSV-----DELQKSV 394
GSY C C G A P CQ+ C D ++T + + D+ Q +
Sbjct: 892 QGSYMCECPPGFSGMDCEEDIDDCLANP-CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM 950
Query: 395 DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCI 452
+ + E C G+C + + S+ C+C G+ G C ++ +EC +C C+
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFD-----GVHCENNINECTESSC--FNGGTCV 1003
Query: 453 NLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG- 511
+ SF C C G+ G E ++EC ++ C TC + G++RC C GY G
Sbjct: 1004 DGINSFSCLCPVGFTGSFCLHE-INECSSHP--CLNEGTCVDGLGTYRCSCPLGYTGKNC 1060
Query: 512 YGLRTVCCVYSCVDIDEC----ANDPTLCENGHCSNTPGGYECDCDVGFTR 558
L +C C + C A LC +G CD+ +R
Sbjct: 1061 QTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR 1111
Score = 100 bits (239), Expect = 2e-20
Identities = 113/408 (27%), Positives = 170/408 (41%), Gaps = 76/408 (18%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDC 176
E+NEC++ P L G C + LG + C C GY KN + VN C C + G C
Sbjct: 1025 EINECSSHPCL-NEGTCVDGLGTYRCSCPLGYT--GKNCQTL-VNLCS--RSPCKNKGTC 1078
Query: 177 HNTEGSFTCHCRPGYKAD--DFSKICVDIDECADN---DALCR-GGRCVNTAGSFRCECG 230
+ C C G+ D + DI + LC+ G C+N + C+C
Sbjct: 1079 VQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCP 1138
Query: 231 HGMELAPDRLSCKD-IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXX 288
G + C++ +DEC+ S C +GA C + +G Y+C C GY +
Sbjct: 1139 LGYTGS----YCEEQLDECA--SNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQ 1192
Query: 289 XXXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCGGGQCRN 345
CQ+ +C++ + C+C G G C + ID+CA G GGQC +
Sbjct: 1193 NQP-----CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGPHCLNGGQCMD 1243
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDEC------ADLISTIIMMSVDEL-------- 390
+G Y+C C +P AG + C+ DI+EC ++ I ++ D L
Sbjct: 1244 RIGGYSCRC----LPGFAGER--CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT 1297
Query: 391 ----QKSVD--PQIPELCGAGSC---HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
+ VD PQ+P L G G+C N F+C+CP G+S G C + G
Sbjct: 1298 GRHCETFVDVCPQMPCLNG-GTCAVASNMPDGFICRCPPGFS-----GARC----QSSCG 1347
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPR 489
C C++ +C C R + C C + G CHP+
Sbjct: 1348 QVKCRKGEQCVHTASGPRCFCPSP-RDCESGCAS-SPC-QHGGSCHPQ 1392
Score = 60.5 bits (140), Expect = 2e-08
Identities = 48/168 (28%), Positives = 72/168 (42%), Gaps = 24/168 (14%)
Query: 395 DPQIPELC-GAGSC--HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
DP C G+C +G C+C G++ + Q + C + C C
Sbjct: 66 DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ---YSTSHPCFVSR-PCLNGGTC 121
Query: 452 INLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
L +++C C+ G+ G C+ D CL++ C +TC F C C TG+ G
Sbjct: 122 HMLSRDTYECTCQVGFTGK--ECQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQ 177
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
C D++EC + P C++G C N PG Y+C C GFT
Sbjct: 178 K-------CE---TDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFT 214
>CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein.
Length = 443
Score = 161 bits (392), Expect = 5e-39
Identities = 88/217 (40%), Positives = 109/217 (50%), Gaps = 11/217 (5%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C PGYE D ++ +CVDV+EC C DCHN GS+ C C GY+ CVDI
Sbjct: 109 CPPGYEPDDQD-SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK--IGPECVDI 165
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ RCVN GSFRC+C G +L P+ SC D++EC + G C N
Sbjct: 166 DECRYR--YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM--GAPCEQRCFNS 220
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
GT+ C C +GY CQ+ CVN PG + C C +G+ L A R
Sbjct: 221 YGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-R 279
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+DIDEC GA C Q C N G Y C T+ V
Sbjct: 280 LCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCV 316
Score = 139 bits (336), Expect = 3e-32
Identities = 103/319 (32%), Positives = 130/319 (40%), Gaps = 49/319 (15%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVD 202
+C GYE D + C DVNEC + C G+ C N G GY +C+
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYG--------GY-------LCLP 82
Query: 203 IDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA-CE 261
ND G C G E D+ SC D+DEC+ C C
Sbjct: 83 RSAAVINDLHGEGPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCH 141
Query: 262 NQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRAD 321
N G+YQC C +GY K CQH CVN PGS+ C C G+ L +
Sbjct: 142 NLPGSYQCTCPDGYR----KIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPN 197
Query: 322 GRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLIST 381
RSC D++EC GA PC +C N+ G++ C C G G +C DIDEC+
Sbjct: 198 NRSCVDVNECDMGA-PC-EQRCFNSYGTFLCRCHQGYELHRDGF--SCSDIDECS----- 248
Query: 382 IIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
LC C N G F C CP GY + + C D DECE G
Sbjct: 249 ---------------YSSYLC-QYRCVNEPGRFSCHCPQGYQLLATR--LCQDIDECESG 290
Query: 442 TCDCHPAADCINLPGSFQC 460
C A C+N G ++C
Sbjct: 291 AHQCSEAQTCVNFHGGYRC 309
Score = 129 bits (312), Expect = 2e-29
Identities = 88/264 (33%), Positives = 121/264 (45%), Gaps = 35/264 (13%)
Query: 305 PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGLVPSAA 363
P SY C +G+ D + CRD++EC C G +C N G Y C V +
Sbjct: 33 PDSY-TECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDL 91
Query: 364 GAK------PTCQDIDECA---DLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
+ P Q + C + + VDE +++ P + CHN GS+
Sbjct: 92 HGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRP----SQDCHNLPGSY 147
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGAT 472
C CPDGY + GP C D DEC C H C+NLPGSF+C+C G++ + +
Sbjct: 148 QCTCPDGYR---KIGPECVDIDECRYRYCQ-H---RCVNLPGSFRCQCEPGFQLGPNNRS 200
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C DV+EC C R C N+ G+F C C GY+ G +SC DIDEC+
Sbjct: 201 CVDVNEC-DMGAPCEQR--CFNSYGTFLCRCHQGYELHRDG-------FSCSDIDECSYS 250
Query: 533 PTLCENGHCSNTPGGYECDCDVGF 556
LC+ C N PG + C C G+
Sbjct: 251 SYLCQY-RCVNEPGRFSCHCPQGY 273
Score = 126 bits (304), Expect = 2e-28
Identities = 73/197 (37%), Positives = 95/197 (48%), Gaps = 12/197 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C NL G + C C GY K CVD++EC C
Sbjct: 122 VDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDIDECRY--RYC-QHR 176
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GSF C C PG++ ++ CVD++EC D A C RC N+ G+F C C G EL
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D SC DIDECS +S +C C N+ G + C C +GY Q
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGY-QLLATRLCQDIDECESGAH 292
Query: 296 RCQ--HSCVNTPGSYHC 310
+C +CVN G Y C
Sbjct: 293 QCSEAQTCVNFHGGYRC 309
Score = 124 bits (298), Expect = 1e-27
Identities = 84/262 (32%), Positives = 118/262 (45%), Gaps = 32/262 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+VNEC P C G +C N GG+ C P +++ + G+G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLC--LP--------------RSAAVINDLHGEGPP 97
Query: 177 HNTE-GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGM- 233
C PGY+ DD CVD+DECA CR + C N GS++C C G
Sbjct: 98 PPVPPAQHPNPCPPGYEPDDQDS-CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR 156
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
++ P+ C DIDEC C + C N G+++C C+ G+ Q +
Sbjct: 157 KIGPE---CVDIDECRYR--YCQH-RCVNLPGSFRCQCEPGF-QLGPNNRSCVDVNECDM 209
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C+ C N+ G++ C C +G+ L DG SC DIDEC+ + C +C N G ++C
Sbjct: 210 GAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRCVNEPGRFSCH 268
Query: 354 CTDGLVPSAAGAKPTCQDIDEC 375
C G A CQDIDEC
Sbjct: 269 CPQGY---QLLATRLCQDIDEC 287
Score = 120 bits (290), Expect = 1e-26
Identities = 102/328 (31%), Positives = 126/328 (38%), Gaps = 61/328 (18%)
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXX 286
EC G E PD C+D++EC C C N G Y C+ +S +
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL-----PRSAAVINDLH 92
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRN 345
QH PG + D SC D+DECA C Q C N
Sbjct: 93 GEGPPPPVPPAQHPNPCPPG----------YEPDDQDSCVDVDECAQALHDCRPSQDCHN 142
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
GSY CTC DG P C DI DE + C
Sbjct: 143 LPGSYQCTCPDGYRKIG----PECVDI---------------DECRY-------RYC-QH 175
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C N GSF CQC G+ + P +C D +EC++G C C N G+F CRC G
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNR-SCVDVNECDMGA-PCEQR--CFNSYGTFLCRCHQG 231
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
+ DG +C D+DEC ++ C R C N G F C C GY+ + C
Sbjct: 232 YELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQ--------LLATRLC 281
Query: 524 VDIDECANDPTLCENGH-CSNTPGGYEC 550
DIDEC + C C N GGY C
Sbjct: 282 QDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 114 bits (275), Expect = 7e-25
Identities = 63/148 (42%), Positives = 79/148 (53%), Gaps = 15/148 (10%)
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVD 477
CP GY +P+ +C D DEC DC P+ DC NLPGS+QC C DG+R G C D+D
Sbjct: 109 CPPGY--EPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDID 166
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC C R C N GSFRC C+ G++ G R SCVD++EC + CE
Sbjct: 167 ECRYRY--CQHR--CVNLPGSFRCQCEPGFQ-LGPNNR------SCVDVNEC-DMGAPCE 214
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
C N+ G + C C G+ DG SC
Sbjct: 215 Q-RCFNSYGTFLCRCHQGYELHRDGFSC 241
Score = 107 bits (258), Expect = 8e-23
Identities = 70/208 (33%), Positives = 94/208 (45%), Gaps = 33/208 (15%)
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
R C N PGSY CTC +G+ R G C DIDEC R C +C N GS+ C C
Sbjct: 135 RPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECR--YRYCQH-RCVNLPGSFRCQCE 189
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G +C D++EC D P C C N+ G+F+
Sbjct: 190 PGF--QLGPNNRSCVDVNEC-------------------DMGAP--CEQ-RCFNSYGTFL 225
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT-CE 474
C+C GY + + G +C+D DEC + C C+N PG F C C G++ C+
Sbjct: 226 CRCHQGYELHRD-GFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQLLATRLCQ 282
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCL 502
D+DEC + C TC N G +RC+
Sbjct: 283 DIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 73.3 bits (172), Expect = 2e-12
Identities = 39/106 (36%), Positives = 50/106 (47%), Gaps = 13/106 (12%)
Query: 462 CRDGWRGDGA-TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
C G+ D +C DVDEC C P C N GS++C C GY+ G
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGP-------- 160
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CVDIDEC C++ C N PG + C C+ GF + RSC+
Sbjct: 161 -ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCV 202
Score = 36.7 bits (81), Expect = 0.22
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC 227
S+T C GY+ D S+ C D++EC C+G +C+N G + C
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
>BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 2 protein.
Length = 443
Score = 161 bits (392), Expect = 5e-39
Identities = 88/217 (40%), Positives = 109/217 (50%), Gaps = 11/217 (5%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C PGYE D ++ +CVDV+EC C DCHN GS+ C C GY+ CVDI
Sbjct: 109 CPPGYEPDDQD-SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK--IGPECVDI 165
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ RCVN GSFRC+C G +L P+ SC D++EC + G C N
Sbjct: 166 DECRYR--YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM--GAPCEQRCFNS 220
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
GT+ C C +GY CQ+ CVN PG + C C +G+ L A R
Sbjct: 221 YGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-R 279
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+DIDEC GA C Q C N G Y C T+ V
Sbjct: 280 LCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCV 316
Score = 139 bits (336), Expect = 3e-32
Identities = 103/319 (32%), Positives = 130/319 (40%), Gaps = 49/319 (15%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVD 202
+C GYE D + C DVNEC + C G+ C N G GY +C+
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYG--------GY-------LCLP 82
Query: 203 IDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA-CE 261
ND G C G E D+ SC D+DEC+ C C
Sbjct: 83 RSAAVINDLHGEGPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCH 141
Query: 262 NQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRAD 321
N G+YQC C +GY K CQH CVN PGS+ C C G+ L +
Sbjct: 142 NLPGSYQCTCPDGYR----KIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPN 197
Query: 322 GRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLIST 381
RSC D++EC GA PC +C N+ G++ C C G G +C DIDEC+
Sbjct: 198 NRSCVDVNECDMGA-PC-EQRCFNSYGTFLCRCHQGYELHRDGF--SCSDIDECS----- 248
Query: 382 IIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
LC C N G F C CP GY + + C D DECE G
Sbjct: 249 ---------------YSSYLC-QYRCVNEPGRFSCHCPQGYQLLATR--LCQDIDECESG 290
Query: 442 TCDCHPAADCINLPGSFQC 460
C A C+N G ++C
Sbjct: 291 AHQCSEAQTCVNFHGGYRC 309
Score = 129 bits (312), Expect = 2e-29
Identities = 88/264 (33%), Positives = 121/264 (45%), Gaps = 35/264 (13%)
Query: 305 PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGLVPSAA 363
P SY C +G+ D + CRD++EC C G +C N G Y C V +
Sbjct: 33 PDSY-TECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDL 91
Query: 364 GAK------PTCQDIDECA---DLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
+ P Q + C + + VDE +++ P + CHN GS+
Sbjct: 92 HGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRP----SQDCHNLPGSY 147
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGAT 472
C CPDGY + GP C D DEC C H C+NLPGSF+C+C G++ + +
Sbjct: 148 QCTCPDGYR---KIGPECVDIDECRYRYCQ-H---RCVNLPGSFRCQCEPGFQLGPNNRS 200
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C DV+EC C R C N+ G+F C C GY+ G +SC DIDEC+
Sbjct: 201 CVDVNEC-DMGAPCEQR--CFNSYGTFLCRCHQGYELHRDG-------FSCSDIDECSYS 250
Query: 533 PTLCENGHCSNTPGGYECDCDVGF 556
LC+ C N PG + C C G+
Sbjct: 251 SYLCQY-RCVNEPGRFSCHCPQGY 273
Score = 126 bits (304), Expect = 2e-28
Identities = 73/197 (37%), Positives = 95/197 (48%), Gaps = 12/197 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C NL G + C C GY K CVD++EC C
Sbjct: 122 VDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDIDECRY--RYC-QHR 176
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GSF C C PG++ ++ CVD++EC D A C RC N+ G+F C C G EL
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D SC DIDECS +S +C C N+ G + C C +GY Q
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGY-QLLATRLCQDIDECESGAH 292
Query: 296 RCQ--HSCVNTPGSYHC 310
+C +CVN G Y C
Sbjct: 293 QCSEAQTCVNFHGGYRC 309
Score = 124 bits (298), Expect = 1e-27
Identities = 84/262 (32%), Positives = 118/262 (45%), Gaps = 32/262 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+VNEC P C G +C N GG+ C P +++ + G+G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLC--LP--------------RSAAVINDLHGEGPP 97
Query: 177 HNTE-GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGM- 233
C PGY+ DD CVD+DECA CR + C N GS++C C G
Sbjct: 98 PPVPPAQHPNPCPPGYEPDDQDS-CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR 156
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
++ P+ C DIDEC C + C N G+++C C+ G+ Q +
Sbjct: 157 KIGPE---CVDIDECRYR--YCQH-RCVNLPGSFRCQCEPGF-QLGPNNRSCVDVNECDM 209
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C+ C N+ G++ C C +G+ L DG SC DIDEC+ + C +C N G ++C
Sbjct: 210 GAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRCVNEPGRFSCH 268
Query: 354 CTDGLVPSAAGAKPTCQDIDEC 375
C G A CQDIDEC
Sbjct: 269 CPQGY---QLLATRLCQDIDEC 287
Score = 120 bits (290), Expect = 1e-26
Identities = 102/328 (31%), Positives = 126/328 (38%), Gaps = 61/328 (18%)
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXX 286
EC G E PD C+D++EC C C N G Y C+ +S +
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL-----PRSAAVINDLH 92
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRN 345
QH PG + D SC D+DECA C Q C N
Sbjct: 93 GEGPPPPVPPAQHPNPCPPG----------YEPDDQDSCVDVDECAQALHDCRPSQDCHN 142
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
GSY CTC DG P C DI DE + C
Sbjct: 143 LPGSYQCTCPDGYRKIG----PECVDI---------------DECRY-------RYC-QH 175
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C N GSF CQC G+ + P +C D +EC++G C C N G+F CRC G
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNR-SCVDVNECDMGA-PCEQR--CFNSYGTFLCRCHQG 231
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
+ DG +C D+DEC ++ C R C N G F C C GY+ + C
Sbjct: 232 YELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQ--------LLATRLC 281
Query: 524 VDIDECANDPTLCENGH-CSNTPGGYEC 550
DIDEC + C C N GGY C
Sbjct: 282 QDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 114 bits (275), Expect = 7e-25
Identities = 63/148 (42%), Positives = 79/148 (53%), Gaps = 15/148 (10%)
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVD 477
CP GY +P+ +C D DEC DC P+ DC NLPGS+QC C DG+R G C D+D
Sbjct: 109 CPPGY--EPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDID 166
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC C R C N GSFRC C+ G++ G R SCVD++EC + CE
Sbjct: 167 ECRYRY--CQHR--CVNLPGSFRCQCEPGFQ-LGPNNR------SCVDVNEC-DMGAPCE 214
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
C N+ G + C C G+ DG SC
Sbjct: 215 Q-RCFNSYGTFLCRCHQGYELHRDGFSC 241
Score = 107 bits (258), Expect = 8e-23
Identities = 70/208 (33%), Positives = 94/208 (45%), Gaps = 33/208 (15%)
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
R C N PGSY CTC +G+ R G C DIDEC R C +C N GS+ C C
Sbjct: 135 RPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECR--YRYCQH-RCVNLPGSFRCQCE 189
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G +C D++EC D P C C N+ G+F+
Sbjct: 190 PGF--QLGPNNRSCVDVNEC-------------------DMGAP--CEQ-RCFNSYGTFL 225
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT-CE 474
C+C GY + + G +C+D DEC + C C+N PG F C C G++ C+
Sbjct: 226 CRCHQGYELHRD-GFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQLLATRLCQ 282
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCL 502
D+DEC + C TC N G +RC+
Sbjct: 283 DIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 73.3 bits (172), Expect = 2e-12
Identities = 39/106 (36%), Positives = 50/106 (47%), Gaps = 13/106 (12%)
Query: 462 CRDGWRGDGA-TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
C G+ D +C DVDEC C P C N GS++C C GY+ G
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGP-------- 160
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CVDIDEC C++ C N PG + C C+ GF + RSC+
Sbjct: 161 -ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCV 202
Score = 36.7 bits (81), Expect = 0.22
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC 227
S+T C GY+ D S+ C D++EC C+G +C+N G + C
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
>AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein.
Length = 443
Score = 161 bits (392), Expect = 5e-39
Identities = 88/217 (40%), Positives = 109/217 (50%), Gaps = 11/217 (5%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C PGYE D ++ +CVDV+EC C DCHN GS+ C C GY+ CVDI
Sbjct: 109 CPPGYEPDDQD-SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK--IGPECVDI 165
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ RCVN GSFRC+C G +L P+ SC D++EC + G C N
Sbjct: 166 DECRYR--YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM--GAPCEQRCFNS 220
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
GT+ C C +GY CQ+ CVN PG + C C +G+ L A R
Sbjct: 221 YGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-R 279
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+DIDEC GA C Q C N G Y C T+ V
Sbjct: 280 LCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCV 316
Score = 139 bits (336), Expect = 3e-32
Identities = 103/319 (32%), Positives = 130/319 (40%), Gaps = 49/319 (15%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVD 202
+C GYE D + C DVNEC + C G+ C N G GY +C+
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYG--------GY-------LCLP 82
Query: 203 IDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA-CE 261
ND G C G E D+ SC D+DEC+ C C
Sbjct: 83 RSAAVINDLHGEGPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCH 141
Query: 262 NQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRAD 321
N G+YQC C +GY K CQH CVN PGS+ C C G+ L +
Sbjct: 142 NLPGSYQCTCPDGYR----KIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPN 197
Query: 322 GRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLIST 381
RSC D++EC GA PC +C N+ G++ C C G G +C DIDEC+
Sbjct: 198 NRSCVDVNECDMGA-PC-EQRCFNSYGTFLCRCHQGYELHRDGF--SCSDIDECS----- 248
Query: 382 IIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
LC C N G F C CP GY + + C D DECE G
Sbjct: 249 ---------------YSSYLC-QYRCVNEPGRFSCHCPQGYQLLATR--LCQDIDECESG 290
Query: 442 TCDCHPAADCINLPGSFQC 460
C A C+N G ++C
Sbjct: 291 AHQCSEAQTCVNFHGGYRC 309
Score = 129 bits (312), Expect = 2e-29
Identities = 88/264 (33%), Positives = 121/264 (45%), Gaps = 35/264 (13%)
Query: 305 PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGLVPSAA 363
P SY C +G+ D + CRD++EC C G +C N G Y C V +
Sbjct: 33 PDSY-TECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDL 91
Query: 364 GAK------PTCQDIDECA---DLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
+ P Q + C + + VDE +++ P + CHN GS+
Sbjct: 92 HGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRP----SQDCHNLPGSY 147
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGAT 472
C CPDGY + GP C D DEC C H C+NLPGSF+C+C G++ + +
Sbjct: 148 QCTCPDGYR---KIGPECVDIDECRYRYCQ-H---RCVNLPGSFRCQCEPGFQLGPNNRS 200
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C DV+EC C R C N+ G+F C C GY+ G +SC DIDEC+
Sbjct: 201 CVDVNEC-DMGAPCEQR--CFNSYGTFLCRCHQGYELHRDG-------FSCSDIDECSYS 250
Query: 533 PTLCENGHCSNTPGGYECDCDVGF 556
LC+ C N PG + C C G+
Sbjct: 251 SYLCQY-RCVNEPGRFSCHCPQGY 273
Score = 126 bits (304), Expect = 2e-28
Identities = 73/197 (37%), Positives = 95/197 (48%), Gaps = 12/197 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C NL G + C C GY K CVD++EC C
Sbjct: 122 VDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDIDECRY--RYC-QHR 176
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GSF C C PG++ ++ CVD++EC D A C RC N+ G+F C C G EL
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D SC DIDECS +S +C C N+ G + C C +GY Q
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGY-QLLATRLCQDIDECESGAH 292
Query: 296 RCQ--HSCVNTPGSYHC 310
+C +CVN G Y C
Sbjct: 293 QCSEAQTCVNFHGGYRC 309
Score = 124 bits (298), Expect = 1e-27
Identities = 84/262 (32%), Positives = 118/262 (45%), Gaps = 32/262 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+VNEC P C G +C N GG+ C P +++ + G+G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLC--LP--------------RSAAVINDLHGEGPP 97
Query: 177 HNTE-GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGM- 233
C PGY+ DD CVD+DECA CR + C N GS++C C G
Sbjct: 98 PPVPPAQHPNPCPPGYEPDDQDS-CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR 156
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
++ P+ C DIDEC C + C N G+++C C+ G+ Q +
Sbjct: 157 KIGPE---CVDIDECRYR--YCQH-RCVNLPGSFRCQCEPGF-QLGPNNRSCVDVNECDM 209
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C+ C N+ G++ C C +G+ L DG SC DIDEC+ + C +C N G ++C
Sbjct: 210 GAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRCVNEPGRFSCH 268
Query: 354 CTDGLVPSAAGAKPTCQDIDEC 375
C G A CQDIDEC
Sbjct: 269 CPQGY---QLLATRLCQDIDEC 287
Score = 120 bits (290), Expect = 1e-26
Identities = 102/328 (31%), Positives = 126/328 (38%), Gaps = 61/328 (18%)
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXX 286
EC G E PD C+D++EC C C N G Y C+ +S +
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL-----PRSAAVINDLH 92
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRN 345
QH PG + D SC D+DECA C Q C N
Sbjct: 93 GEGPPPPVPPAQHPNPCPPG----------YEPDDQDSCVDVDECAQALHDCRPSQDCHN 142
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
GSY CTC DG P C DI DE + C
Sbjct: 143 LPGSYQCTCPDGYRKIG----PECVDI---------------DECRY-------RYC-QH 175
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C N GSF CQC G+ + P +C D +EC++G C C N G+F CRC G
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNR-SCVDVNECDMGA-PCEQR--CFNSYGTFLCRCHQG 231
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
+ DG +C D+DEC ++ C R C N G F C C GY+ + C
Sbjct: 232 YELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQ--------LLATRLC 281
Query: 524 VDIDECANDPTLCENGH-CSNTPGGYEC 550
DIDEC + C C N GGY C
Sbjct: 282 QDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 114 bits (275), Expect = 7e-25
Identities = 63/148 (42%), Positives = 79/148 (53%), Gaps = 15/148 (10%)
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVD 477
CP GY +P+ +C D DEC DC P+ DC NLPGS+QC C DG+R G C D+D
Sbjct: 109 CPPGY--EPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDID 166
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC C R C N GSFRC C+ G++ G R SCVD++EC + CE
Sbjct: 167 ECRYRY--CQHR--CVNLPGSFRCQCEPGFQ-LGPNNR------SCVDVNEC-DMGAPCE 214
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
C N+ G + C C G+ DG SC
Sbjct: 215 Q-RCFNSYGTFLCRCHQGYELHRDGFSC 241
Score = 107 bits (258), Expect = 8e-23
Identities = 70/208 (33%), Positives = 94/208 (45%), Gaps = 33/208 (15%)
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
R C N PGSY CTC +G+ R G C DIDEC R C +C N GS+ C C
Sbjct: 135 RPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECR--YRYCQH-RCVNLPGSFRCQCE 189
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G +C D++EC D P C C N+ G+F+
Sbjct: 190 PGF--QLGPNNRSCVDVNEC-------------------DMGAP--CEQ-RCFNSYGTFL 225
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT-CE 474
C+C GY + + G +C+D DEC + C C+N PG F C C G++ C+
Sbjct: 226 CRCHQGYELHRD-GFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQLLATRLCQ 282
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCL 502
D+DEC + C TC N G +RC+
Sbjct: 283 DIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 73.3 bits (172), Expect = 2e-12
Identities = 39/106 (36%), Positives = 50/106 (47%), Gaps = 13/106 (12%)
Query: 462 CRDGWRGDGA-TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
C G+ D +C DVDEC C P C N GS++C C GY+ G
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGP-------- 160
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CVDIDEC C++ C N PG + C C+ GF + RSC+
Sbjct: 161 -ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCV 202
Score = 36.7 bits (81), Expect = 0.22
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC 227
S+T C GY+ D S+ C D++EC C+G +C+N G + C
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
>AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein.
Length = 443
Score = 161 bits (392), Expect = 5e-39
Identities = 88/217 (40%), Positives = 109/217 (50%), Gaps = 11/217 (5%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C PGYE D ++ +CVDV+EC C DCHN GS+ C C GY+ CVDI
Sbjct: 109 CPPGYEPDDQD-SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK--IGPECVDI 165
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ RCVN GSFRC+C G +L P+ SC D++EC + G C N
Sbjct: 166 DECRYR--YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM--GAPCEQRCFNS 220
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
GT+ C C +GY CQ+ CVN PG + C C +G+ L A R
Sbjct: 221 YGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-R 279
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+DIDEC GA C Q C N G Y C T+ V
Sbjct: 280 LCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCV 316
Score = 139 bits (336), Expect = 3e-32
Identities = 103/319 (32%), Positives = 130/319 (40%), Gaps = 49/319 (15%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVD 202
+C GYE D + C DVNEC + C G+ C N G GY +C+
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYG--------GY-------LCLP 82
Query: 203 IDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA-CE 261
ND G C G E D+ SC D+DEC+ C C
Sbjct: 83 RSAAVINDLHGEGPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCH 141
Query: 262 NQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRAD 321
N G+YQC C +GY K CQH CVN PGS+ C C G+ L +
Sbjct: 142 NLPGSYQCTCPDGYR----KIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPN 197
Query: 322 GRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLIST 381
RSC D++EC GA PC +C N+ G++ C C G G +C DIDEC+
Sbjct: 198 NRSCVDVNECDMGA-PC-EQRCFNSYGTFLCRCHQGYELHRDGF--SCSDIDECS----- 248
Query: 382 IIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
LC C N G F C CP GY + + C D DECE G
Sbjct: 249 ---------------YSSYLC-QYRCVNEPGRFSCHCPQGYQLLATR--LCQDIDECESG 290
Query: 442 TCDCHPAADCINLPGSFQC 460
C A C+N G ++C
Sbjct: 291 AHQCSEAQTCVNFHGGYRC 309
Score = 129 bits (312), Expect = 2e-29
Identities = 88/264 (33%), Positives = 121/264 (45%), Gaps = 35/264 (13%)
Query: 305 PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGLVPSAA 363
P SY C +G+ D + CRD++EC C G +C N G Y C V +
Sbjct: 33 PDSY-TECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDL 91
Query: 364 GAK------PTCQDIDECA---DLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
+ P Q + C + + VDE +++ P + CHN GS+
Sbjct: 92 HGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRP----SQDCHNLPGSY 147
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGAT 472
C CPDGY + GP C D DEC C H C+NLPGSF+C+C G++ + +
Sbjct: 148 QCTCPDGYR---KIGPECVDIDECRYRYCQ-H---RCVNLPGSFRCQCEPGFQLGPNNRS 200
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C DV+EC C R C N+ G+F C C GY+ G +SC DIDEC+
Sbjct: 201 CVDVNEC-DMGAPCEQR--CFNSYGTFLCRCHQGYELHRDG-------FSCSDIDECSYS 250
Query: 533 PTLCENGHCSNTPGGYECDCDVGF 556
LC+ C N PG + C C G+
Sbjct: 251 SYLCQY-RCVNEPGRFSCHCPQGY 273
Score = 126 bits (304), Expect = 2e-28
Identities = 73/197 (37%), Positives = 95/197 (48%), Gaps = 12/197 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C NL G + C C GY K CVD++EC C
Sbjct: 122 VDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDIDECRY--RYC-QHR 176
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GSF C C PG++ ++ CVD++EC D A C RC N+ G+F C C G EL
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D SC DIDECS +S +C C N+ G + C C +GY Q
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGY-QLLATRLCQDIDECESGAH 292
Query: 296 RCQ--HSCVNTPGSYHC 310
+C +CVN G Y C
Sbjct: 293 QCSEAQTCVNFHGGYRC 309
Score = 124 bits (298), Expect = 1e-27
Identities = 84/262 (32%), Positives = 118/262 (45%), Gaps = 32/262 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+VNEC P C G +C N GG+ C P +++ + G+G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLC--LP--------------RSAAVINDLHGEGPP 97
Query: 177 HNTE-GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGM- 233
C PGY+ DD CVD+DECA CR + C N GS++C C G
Sbjct: 98 PPVPPAQHPNPCPPGYEPDDQDS-CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR 156
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
++ P+ C DIDEC C + C N G+++C C+ G+ Q +
Sbjct: 157 KIGPE---CVDIDECRYR--YCQH-RCVNLPGSFRCQCEPGF-QLGPNNRSCVDVNECDM 209
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C+ C N+ G++ C C +G+ L DG SC DIDEC+ + C +C N G ++C
Sbjct: 210 GAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRCVNEPGRFSCH 268
Query: 354 CTDGLVPSAAGAKPTCQDIDEC 375
C G A CQDIDEC
Sbjct: 269 CPQGY---QLLATRLCQDIDEC 287
Score = 120 bits (290), Expect = 1e-26
Identities = 102/328 (31%), Positives = 126/328 (38%), Gaps = 61/328 (18%)
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXX 286
EC G E PD C+D++EC C C N G Y C+ +S +
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL-----PRSAAVINDLH 92
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRN 345
QH PG + D SC D+DECA C Q C N
Sbjct: 93 GEGPPPPVPPAQHPNPCPPG----------YEPDDQDSCVDVDECAQALHDCRPSQDCHN 142
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
GSY CTC DG P C DI DE + C
Sbjct: 143 LPGSYQCTCPDGYRKIG----PECVDI---------------DECRY-------RYC-QH 175
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C N GSF CQC G+ + P +C D +EC++G C C N G+F CRC G
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNR-SCVDVNECDMGA-PCEQR--CFNSYGTFLCRCHQG 231
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
+ DG +C D+DEC ++ C R C N G F C C GY+ + C
Sbjct: 232 YELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQ--------LLATRLC 281
Query: 524 VDIDECANDPTLCENGH-CSNTPGGYEC 550
DIDEC + C C N GGY C
Sbjct: 282 QDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 114 bits (275), Expect = 7e-25
Identities = 63/148 (42%), Positives = 79/148 (53%), Gaps = 15/148 (10%)
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVD 477
CP GY +P+ +C D DEC DC P+ DC NLPGS+QC C DG+R G C D+D
Sbjct: 109 CPPGY--EPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDID 166
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC C R C N GSFRC C+ G++ G R SCVD++EC + CE
Sbjct: 167 ECRYRY--CQHR--CVNLPGSFRCQCEPGFQ-LGPNNR------SCVDVNEC-DMGAPCE 214
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
C N+ G + C C G+ DG SC
Sbjct: 215 Q-RCFNSYGTFLCRCHQGYELHRDGFSC 241
Score = 107 bits (258), Expect = 8e-23
Identities = 70/208 (33%), Positives = 94/208 (45%), Gaps = 33/208 (15%)
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
R C N PGSY CTC +G+ R G C DIDEC R C +C N GS+ C C
Sbjct: 135 RPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECR--YRYCQH-RCVNLPGSFRCQCE 189
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G +C D++EC D P C C N+ G+F+
Sbjct: 190 PGF--QLGPNNRSCVDVNEC-------------------DMGAP--CEQ-RCFNSYGTFL 225
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT-CE 474
C+C GY + + G +C+D DEC + C C+N PG F C C G++ C+
Sbjct: 226 CRCHQGYELHRD-GFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQLLATRLCQ 282
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCL 502
D+DEC + C TC N G +RC+
Sbjct: 283 DIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 73.3 bits (172), Expect = 2e-12
Identities = 39/106 (36%), Positives = 50/106 (47%), Gaps = 13/106 (12%)
Query: 462 CRDGWRGDGA-TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
C G+ D +C DVDEC C P C N GS++C C GY+ G
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGP-------- 160
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CVDIDEC C++ C N PG + C C+ GF + RSC+
Sbjct: 161 -ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCV 202
Score = 36.7 bits (81), Expect = 0.22
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC 227
S+T C GY+ D S+ C D++EC C+G +C+N G + C
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
>AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 2 protein.
Length = 443
Score = 161 bits (392), Expect = 5e-39
Identities = 88/217 (40%), Positives = 109/217 (50%), Gaps = 11/217 (5%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C PGYE D ++ +CVDV+EC C DCHN GS+ C C GY+ CVDI
Sbjct: 109 CPPGYEPDDQD-SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK--IGPECVDI 165
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ RCVN GSFRC+C G +L P+ SC D++EC + G C N
Sbjct: 166 DECRYR--YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM--GAPCEQRCFNS 220
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
GT+ C C +GY CQ+ CVN PG + C C +G+ L A R
Sbjct: 221 YGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-R 279
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+DIDEC GA C Q C N G Y C T+ V
Sbjct: 280 LCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCV 316
Score = 139 bits (336), Expect = 3e-32
Identities = 103/319 (32%), Positives = 130/319 (40%), Gaps = 49/319 (15%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVD 202
+C GYE D + C DVNEC + C G+ C N G GY +C+
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYG--------GY-------LCLP 82
Query: 203 IDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA-CE 261
ND G C G E D+ SC D+DEC+ C C
Sbjct: 83 RSAAVINDLHGEGPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCH 141
Query: 262 NQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRAD 321
N G+YQC C +GY K CQH CVN PGS+ C C G+ L +
Sbjct: 142 NLPGSYQCTCPDGYR----KIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPN 197
Query: 322 GRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLIST 381
RSC D++EC GA PC +C N+ G++ C C G G +C DIDEC+
Sbjct: 198 NRSCVDVNECDMGA-PC-EQRCFNSYGTFLCRCHQGYELHRDGF--SCSDIDECS----- 248
Query: 382 IIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
LC C N G F C CP GY + + C D DECE G
Sbjct: 249 ---------------YSSYLC-QYRCVNEPGRFSCHCPQGYQLLATR--LCQDIDECESG 290
Query: 442 TCDCHPAADCINLPGSFQC 460
C A C+N G ++C
Sbjct: 291 AHQCSEAQTCVNFHGGYRC 309
Score = 129 bits (312), Expect = 2e-29
Identities = 88/264 (33%), Positives = 121/264 (45%), Gaps = 35/264 (13%)
Query: 305 PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGLVPSAA 363
P SY C +G+ D + CRD++EC C G +C N G Y C V +
Sbjct: 33 PDSY-TECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDL 91
Query: 364 GAK------PTCQDIDECA---DLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
+ P Q + C + + VDE +++ P + CHN GS+
Sbjct: 92 HGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRP----SQDCHNLPGSY 147
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGAT 472
C CPDGY + GP C D DEC C H C+NLPGSF+C+C G++ + +
Sbjct: 148 QCTCPDGYR---KIGPECVDIDECRYRYCQ-H---RCVNLPGSFRCQCEPGFQLGPNNRS 200
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C DV+EC C R C N+ G+F C C GY+ G +SC DIDEC+
Sbjct: 201 CVDVNEC-DMGAPCEQR--CFNSYGTFLCRCHQGYELHRDG-------FSCSDIDECSYS 250
Query: 533 PTLCENGHCSNTPGGYECDCDVGF 556
LC+ C N PG + C C G+
Sbjct: 251 SYLCQY-RCVNEPGRFSCHCPQGY 273
Score = 126 bits (304), Expect = 2e-28
Identities = 73/197 (37%), Positives = 95/197 (48%), Gaps = 12/197 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C NL G + C C GY K CVD++EC C
Sbjct: 122 VDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDIDECRY--RYC-QHR 176
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GSF C C PG++ ++ CVD++EC D A C RC N+ G+F C C G EL
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D SC DIDECS +S +C C N+ G + C C +GY Q
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGY-QLLATRLCQDIDECESGAH 292
Query: 296 RCQ--HSCVNTPGSYHC 310
+C +CVN G Y C
Sbjct: 293 QCSEAQTCVNFHGGYRC 309
Score = 124 bits (298), Expect = 1e-27
Identities = 84/262 (32%), Positives = 118/262 (45%), Gaps = 32/262 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+VNEC P C G +C N GG+ C P +++ + G+G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLC--LP--------------RSAAVINDLHGEGPP 97
Query: 177 HNTE-GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGM- 233
C PGY+ DD CVD+DECA CR + C N GS++C C G
Sbjct: 98 PPVPPAQHPNPCPPGYEPDDQDS-CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR 156
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
++ P+ C DIDEC C + C N G+++C C+ G+ Q +
Sbjct: 157 KIGPE---CVDIDECRYR--YCQH-RCVNLPGSFRCQCEPGF-QLGPNNRSCVDVNECDM 209
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C+ C N+ G++ C C +G+ L DG SC DIDEC+ + C +C N G ++C
Sbjct: 210 GAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRCVNEPGRFSCH 268
Query: 354 CTDGLVPSAAGAKPTCQDIDEC 375
C G A CQDIDEC
Sbjct: 269 CPQGY---QLLATRLCQDIDEC 287
Score = 120 bits (290), Expect = 1e-26
Identities = 102/328 (31%), Positives = 126/328 (38%), Gaps = 61/328 (18%)
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXX 286
EC G E PD C+D++EC C C N G Y C+ +S +
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL-----PRSAAVINDLH 92
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRN 345
QH PG + D SC D+DECA C Q C N
Sbjct: 93 GEGPPPPVPPAQHPNPCPPG----------YEPDDQDSCVDVDECAQALHDCRPSQDCHN 142
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
GSY CTC DG P C DI DE + C
Sbjct: 143 LPGSYQCTCPDGYRKIG----PECVDI---------------DECRY-------RYC-QH 175
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C N GSF CQC G+ + P +C D +EC++G C C N G+F CRC G
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNR-SCVDVNECDMGA-PCEQR--CFNSYGTFLCRCHQG 231
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
+ DG +C D+DEC ++ C R C N G F C C GY+ + C
Sbjct: 232 YELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQ--------LLATRLC 281
Query: 524 VDIDECANDPTLCENGH-CSNTPGGYEC 550
DIDEC + C C N GGY C
Sbjct: 282 QDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 114 bits (275), Expect = 7e-25
Identities = 63/148 (42%), Positives = 79/148 (53%), Gaps = 15/148 (10%)
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVD 477
CP GY +P+ +C D DEC DC P+ DC NLPGS+QC C DG+R G C D+D
Sbjct: 109 CPPGY--EPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDID 166
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC C R C N GSFRC C+ G++ G R SCVD++EC + CE
Sbjct: 167 ECRYRY--CQHR--CVNLPGSFRCQCEPGFQ-LGPNNR------SCVDVNEC-DMGAPCE 214
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
C N+ G + C C G+ DG SC
Sbjct: 215 Q-RCFNSYGTFLCRCHQGYELHRDGFSC 241
Score = 107 bits (258), Expect = 8e-23
Identities = 70/208 (33%), Positives = 94/208 (45%), Gaps = 33/208 (15%)
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
R C N PGSY CTC +G+ R G C DIDEC R C +C N GS+ C C
Sbjct: 135 RPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECR--YRYCQH-RCVNLPGSFRCQCE 189
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G +C D++EC D P C C N+ G+F+
Sbjct: 190 PGF--QLGPNNRSCVDVNEC-------------------DMGAP--CEQ-RCFNSYGTFL 225
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT-CE 474
C+C GY + + G +C+D DEC + C C+N PG F C C G++ C+
Sbjct: 226 CRCHQGYELHRD-GFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQLLATRLCQ 282
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCL 502
D+DEC + C TC N G +RC+
Sbjct: 283 DIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 73.3 bits (172), Expect = 2e-12
Identities = 39/106 (36%), Positives = 50/106 (47%), Gaps = 13/106 (12%)
Query: 462 CRDGWRGDGA-TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
C G+ D +C DVDEC C P C N GS++C C GY+ G
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGP-------- 160
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CVDIDEC C++ C N PG + C C+ GF + RSC+
Sbjct: 161 -ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCV 202
Score = 36.7 bits (81), Expect = 0.22
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC 227
S+T C GY+ D S+ C D++EC C+G +C+N G + C
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein
variant protein.
Length = 2067
Score = 161 bits (392), Expect = 5e-39
Identities = 132/463 (28%), Positives = 200/463 (43%), Gaps = 73/463 (15%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
Q +V+ECA+ P C +G +C + +TC C GY + H VD++EC+ C G
Sbjct: 38 QYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGY---TGTHCEVDIDECD--PDPCHYG 90
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGM 233
C + +FTC CRPGY +I+EC+ CR GG C + ++ C C G
Sbjct: 91 SCKDGVATFTCLCRPGYTGHHCE---TNINECSSQP--CRHGGTCQDRDNAYLCFCLKG- 144
Query: 234 ELAPDRLSCK-DIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
P +C+ ++D+C+ S C +G C +++ Y+C C+ GY S +
Sbjct: 145 TTGP---NCEINLDDCA--SSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPC 199
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
+C + + C C EG+H D +++EC + PC G CR+++ Y C
Sbjct: 200 HNG---GTCEDGINGFTCRCPEGYH---DPTCLSEVNEC--NSNPCVHGACRDSLNGYKC 251
Query: 353 TCTDGL------VPSAAGAKPTCQDIDECADLISTIIM-----MSVDELQKSVDPQIPEL 401
C G + + C + C D+ S + S Q +++
Sbjct: 252 DCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNP 311
Query: 402 C-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTC---DCHPAADCINLPG- 456
C G+C + + + C C + P G C E L C C +C
Sbjct: 312 CLNQGTCIDDVAGYKCNC-----LLPYTGATC----EVVLAPCAPSPCRNGGECRQSEDY 362
Query: 457 -SFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
SF C C GW+G TCE D++EC+ + C A+C NT G +RC C GY G
Sbjct: 363 ESFSCVCPTGWQGQ--TCEVDINECVLS--PCRHGASCQNTHGGYRCHCQAGYSGRN--- 415
Query: 515 RTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
C DID+C +P C N G C++ CDC GF
Sbjct: 416 ----CE---TDIDDCRPNP--CHNGGSCTDGINTAFCDCLPGF 449
Score = 158 bits (384), Expect = 4e-38
Identities = 140/451 (31%), Positives = 192/451 (42%), Gaps = 87/451 (19%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
EVNEC + P C HG CR+ L G+ CDC PG+ S + ++ NECE V G G C
Sbjct: 228 EVNECNSNP--CVHGACRDSLNGYKCDCDPGW---SGTNCDINNNECESNPCVNG-GTCK 281
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
+ + C CR G+ + +I+ECA N L G C++ ++C C L P
Sbjct: 282 DMTSGYVCTCREGFSGPNCQ---TNINECASNPCL-NQGTCIDDVAGYKCNC-----LLP 332
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQ---CVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ ++ C NG Q Y+ CVC G+ T +
Sbjct: 333 YTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCE-----VDINECVL 387
Query: 295 XRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C+H SC NT G Y C C+ G+ GR+C DID+C PC GG C + + +
Sbjct: 388 SPCRHGASCQNTHGGYRCHCQAGY----SGRNCETDIDDCR--PNPCHNGGSCTDGINTA 441
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG-SCHN 409
C C G + +DI+ECA DP C G +C +
Sbjct: 442 FCDCLPGFRGTFCE-----EDINECAS-----------------DP-----CRNGANCTD 474
Query: 410 TIGSFVCQCPDGYS-VKPEQG-PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR 467
+ S+ C CP G+S + E P CT+ GTC D IN SF C C G+
Sbjct: 475 CVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTC-----VDGIN---SFTCLCPPGF- 525
Query: 468 GDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI 526
G+ C+ DV+EC ++ C TC + GS+RC C GY G V+ C D
Sbjct: 526 -TGSYCQHDVNEC--DSQPCLHGGTCQDGCGSYRCTCPQGYTGP----NCQNLVHWC-DS 577
Query: 527 DECANDPTLCENGHCSNTPGGYECDCDVGFT 557
C N G C T Y C+C G+T
Sbjct: 578 SPCKN------GGKCWQTHTQYRCECPSGWT 602
Score = 153 bits (372), Expect = 1e-36
Identities = 130/465 (27%), Positives = 192/465 (41%), Gaps = 68/465 (14%)
Query: 122 CAAFPGLCGHGRCRNL--LGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG-DCH 177
CA P G G CR F+C C G++ TC VD+NEC + C G C
Sbjct: 345 CAPSPCRNG-GECRQSEDYESFSCVCPTGWQ----GQTCEVDINECVL--SPCRHGASCQ 397
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT G + CHC+ GY + DID+C N GG C + + C+C G
Sbjct: 398 NTHGGYRCHCQAGYSGRNCE---TDIDDCRPNPCH-NGGSCTDGINTAFCDCLPGFR--- 450
Query: 238 DRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+DI+EC+ S C NGA C + + +Y C C G++ +++
Sbjct: 451 GTFCEEDINECA--SDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG 508
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTC 354
+CV+ S+ C C G+ G C+ D++EC ++PC GG C++ GSY CTC
Sbjct: 509 ---TCVDGINSFTCLCPPGF----TGSYCQHDVNEC--DSQPCLHGGTCQDGCGSYRCTC 559
Query: 355 TDGLV--------------PSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKS 393
G P G K C+ L + +S + +
Sbjct: 560 PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQR 619
Query: 394 VDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADC 451
+ LC G C + + C+C GY+ G C D DEC C A C
Sbjct: 620 QGVDVARLCQHGGLCVDAGNTHHCRCQAGYT-----GSYCEDLVDECS--PSPCQNGATC 672
Query: 452 INLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG 511
+ G + C+C G+ G + E++DECL++ C TC + +++C C G +G
Sbjct: 673 TDYLGGYSCKCVAGYHGVNCS-EEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQGVH 729
Query: 512 YGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
+ C +D + P NG C + GGY C C GF
Sbjct: 730 CEINVDDCN---PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGF 771
Score = 149 bits (362), Expect = 2e-35
Identities = 120/428 (28%), Positives = 176/428 (41%), Gaps = 66/428 (15%)
Query: 118 EVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++NECA+ P C +G C + + +TC C G+ + D E +G G C
Sbjct: 457 DINECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG----GTC 510
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
+ SFTC C PG+ S D++EC D+ GG C + GS+RC C G
Sbjct: 511 VDGINSFTCLCPPGFTG---SYCQHDVNEC-DSQPCLHGGTCQDGCGSYRCTCPQGYT-G 565
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ-----STVKSHXXXXXXXX 291
P+ C+++ +S + G C Y+C C G+ +V
Sbjct: 566 PN---CQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGV 622
Query: 292 XXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPC-GGGQCRNTV 347
CQH CV+ ++HC C+ G+ G C D +DEC+ PC G C + +
Sbjct: 623 DVARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDLVDECSPS--PCQNGATCTDYL 676
Query: 348 GSYTCTCTDGLVPSAAGAK------PTCQDIDECADLISTI------------IMMSVDE 389
G Y+C C G + CQ+ C DL +T ++VD+
Sbjct: 677 GGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDD 736
Query: 390 LQKSVDP--QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCH 446
VDP + P+ G+C + +G + C CP G+ G C D +EC CD
Sbjct: 737 CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV-----GERCEGDVNECLSNPCDAR 791
Query: 447 PAADCINLPGSFQCRCRDGWRGDGATCEDV-DEC----LTNNGGCHPRATCANTDGSFRC 501
+C+ F C CR G G CE V + C N G C A +NT F C
Sbjct: 792 GTQNCVQRVNDFHCECRAG--HTGRRCESVINGCKGKPCKNGGTC---AVASNTARGFIC 846
Query: 502 LCDTGYKG 509
C G++G
Sbjct: 847 KCPAGFEG 854
Score = 147 bits (356), Expect = 1e-34
Identities = 140/477 (29%), Positives = 204/477 (42%), Gaps = 89/477 (18%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG- 174
+ +ECA+ P L +GRC + + F C+C G+ H C DV+EC C +G
Sbjct: 1 VNTDECASSPCL-HNGRCLDKINEFQCECPTGF----TGHLCQYDVDEC--ASTPCKNGA 53
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + ++TC C GY VDIDEC D D C G C + +F C C G
Sbjct: 54 KCLDGPNTYTCVCTEGYTGTHCE---VDIDEC-DPDP-CHYGSCKDGVATFTCLCRPGY- 107
Query: 235 LAPDRLSCK-DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
C+ +I+ECS S C + G C+++ Y C C +G T +
Sbjct: 108 ---TGHHCETNINECS--SQPCRHGGTCQDRDNAYLCFCLKG----TTGPNCEINLDDCA 158
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
+C++ Y C C G+ G C +IDECAG PC GG C + + +
Sbjct: 159 SSPCDSGTCLDKIDGYECACEPGY----TGSMCNINIDECAG--NPCHNGGTCEDGINGF 212
Query: 351 TCTCTDGLVPSAAGAKPTC-QDIDECAD--LISTIIMMSVDELQKSVDP----------- 396
TC C +G PTC +++EC + S++ + DP
Sbjct: 213 TCRCPEGY------HDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINN 266
Query: 397 ---QIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCI 452
+ G+C + +VC C +G+S GP C T+ +EC + C CI
Sbjct: 267 NECESNPCVNGGTCKDMTSGYVCTCREGFS-----GPNCQTNINEC--ASNPCLNQGTCI 319
Query: 453 NLPGSFQCRCRDGWRGDGATCEDV-DECLTNNGGCHPRATCANTDG--SFRCLCDTGYKG 509
+ ++C C + GATCE V C + C C ++ SF C+C TG++G
Sbjct: 320 DDVAGYKCNCLLPY--TGATCEVVLAPCAPS--PCRNGGECRQSEDYESFSCVCPTGWQG 375
Query: 510 DGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVGFTRAADGRSC 565
C VDI+EC P C +G C NT GGY C C G++ GR+C
Sbjct: 376 Q-------TCE---VDINECVLSP--CRHGASCQNTHGGYRCHCQAGYS----GRNC 416
Score = 138 bits (334), Expect = 5e-32
Identities = 127/485 (26%), Positives = 199/485 (41%), Gaps = 82/485 (16%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
++++NEC P C HG C+N GG+ C C GY S + D+++C C +G
Sbjct: 379 EVDINECVLSP--CRHGASCQNTHGGYRCHCQAGY---SGRNCETDIDDCR--PNPCHNG 431
Query: 175 -DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PG++ + DI+ECA +D G C + S+ C C G
Sbjct: 432 GSCTDGINTAFCDCLPGFRGTFCEE---DINECA-SDPCRNGANCTDCVDSYTCTCPAGF 487
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX-X 292
+ D E S +G G C + + ++ C+C G+ S +
Sbjct: 488 SGIHCENNTPDCTESSCFNG----GTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCL 543
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQCRNTVGSYT 351
CQ C GSY CTC +G+ G +C+++ + PC GG+C T Y
Sbjct: 544 HGGTCQDGC----GSYRCTCPQGY----TGPNCQNLVHWCDSS-PCKNGGKCWQTHTQYR 594
Query: 352 CTCTDGL------VPSAA----------GAKPTCQDIDECADLISTIIMM-----SVDEL 390
C C G VPS + CQ C D +T +
Sbjct: 595 CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYC 654
Query: 391 QKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
+ VD P C G+ C + +G + C+C GY G C+++ DEC + C
Sbjct: 655 EDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY-----HGVNCSEEIDECL--SHPCQNG 707
Query: 449 ADCINLPGSFQCRCRDGWRGDGATCE-DVDEC------LTNNGGCHPRATCANTDGSFRC 501
C++LP +++C C G +G CE +VD+C ++ + C TC + G + C
Sbjct: 708 GTCLDLPNTYKCSCPRGTQG--VHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC 765
Query: 502 LCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGFTRAA 560
C G+ G+ C D++EC ++P +C + C+C G T
Sbjct: 766 TCPPGFVGER-------CE---GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT--- 812
Query: 561 DGRSC 565
GR C
Sbjct: 813 -GRRC 816
Score = 118 bits (283), Expect = 7e-26
Identities = 114/430 (26%), Positives = 170/430 (39%), Gaps = 62/430 (14%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYE-KDSKN--HTCVDVNECEIVDGVCG 172
Q +VNEC + P L G G C++ G + C C GY + +N H C D + C+
Sbjct: 531 QHDVNECDSQPCLHG-GTCQDGCGSYRCTCPQGYTGPNCQNLVHWC-DSSPCK------N 582
Query: 173 DGDCHNTEGSFTCHCRPGYKA--DDFSKICVDID---ECADNDALCR-GGRCVNTAGSFR 226
G C T + C C G+ D + ++ + D LC+ GG CV+ +
Sbjct: 583 GGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH 642
Query: 227 CECGHGMELAPDRLSCKD-IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHX 284
C C G + C+D +DECS + C NGA C + +G Y C C GY
Sbjct: 643 CRCQAGYTGS----YCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 696
Query: 285 XXXXXXXXXXXRCQH--SCVNTPGSYHCTC---REGWHLRADGRSCRD-IDECAGGARPC 338
CQ+ +C++ P +Y C+C +G H + C +D + +
Sbjct: 697 DECLSHP-----CQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCF 751
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAA-GAKPTC-------QDIDECADLISTI-IMMSVDE 389
G C + VG Y+CTC G V G C + C ++
Sbjct: 752 NNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH 811
Query: 390 LQKSVDPQIPELCG-----AGSC---HNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
+ + I G G+C NT F+C+CP G+ +G C ++D G
Sbjct: 812 TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF-----EGATC-ENDARTCG 865
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGS--F 499
+ C CI+ P S C C + G CL N C+ + TC T S +
Sbjct: 866 SLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGN-PCYNQGTCEPTSESPFY 924
Query: 500 RCLCDTGYKG 509
RCLC + G
Sbjct: 925 RCLCPAKFNG 934
>AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding protein
1 (MBP1) protein.
Length = 443
Score = 161 bits (392), Expect = 5e-39
Identities = 88/217 (40%), Positives = 109/217 (50%), Gaps = 11/217 (5%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C PGYE D ++ +CVDV+EC C DCHN GS+ C C GY+ CVDI
Sbjct: 109 CPPGYEPDDQD-SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK--IGPECVDI 165
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ RCVN GSFRC+C G +L P+ SC D++EC + G C N
Sbjct: 166 DECRYR--YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM--GAPCEQRCFNS 220
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
GT+ C C +GY CQ+ CVN PG + C C +G+ L A R
Sbjct: 221 YGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-R 279
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+DIDEC GA C Q C N G Y C T+ V
Sbjct: 280 LCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCV 316
Score = 139 bits (336), Expect = 3e-32
Identities = 103/319 (32%), Positives = 130/319 (40%), Gaps = 49/319 (15%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVD 202
+C GYE D + C DVNEC + C G+ C N G GY +C+
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYG--------GY-------LCLP 82
Query: 203 IDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA-CE 261
ND G C G E D+ SC D+DEC+ C C
Sbjct: 83 RSAAVINDLHGEGPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCH 141
Query: 262 NQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRAD 321
N G+YQC C +GY K CQH CVN PGS+ C C G+ L +
Sbjct: 142 NLPGSYQCTCPDGYR----KIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPN 197
Query: 322 GRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLIST 381
RSC D++EC GA PC +C N+ G++ C C G G +C DIDEC+
Sbjct: 198 NRSCVDVNECDMGA-PC-EQRCFNSYGTFLCRCHQGYELHRDGF--SCSDIDECS----- 248
Query: 382 IIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
LC C N G F C CP GY + + C D DECE G
Sbjct: 249 ---------------YSSYLC-QYRCVNEPGRFSCHCPQGYQLLATR--LCQDIDECESG 290
Query: 442 TCDCHPAADCINLPGSFQC 460
C A C+N G ++C
Sbjct: 291 AHQCSEAQTCVNFHGGYRC 309
Score = 129 bits (312), Expect = 2e-29
Identities = 88/264 (33%), Positives = 121/264 (45%), Gaps = 35/264 (13%)
Query: 305 PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGLVPSAA 363
P SY C +G+ D + CRD++EC C G +C N G Y C V +
Sbjct: 33 PDSY-TECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDL 91
Query: 364 GAK------PTCQDIDECA---DLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
+ P Q + C + + VDE +++ P + CHN GS+
Sbjct: 92 HGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRP----SQDCHNLPGSY 147
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGAT 472
C CPDGY + GP C D DEC C H C+NLPGSF+C+C G++ + +
Sbjct: 148 QCTCPDGYR---KIGPECVDIDECRYRYCQ-H---RCVNLPGSFRCQCEPGFQLGPNNRS 200
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C DV+EC C R C N+ G+F C C GY+ G +SC DIDEC+
Sbjct: 201 CVDVNEC-DMGAPCEQR--CFNSYGTFLCRCHQGYELHRDG-------FSCSDIDECSYS 250
Query: 533 PTLCENGHCSNTPGGYECDCDVGF 556
LC+ C N PG + C C G+
Sbjct: 251 SYLCQY-RCVNEPGRFSCHCPQGY 273
Score = 126 bits (304), Expect = 2e-28
Identities = 73/197 (37%), Positives = 95/197 (48%), Gaps = 12/197 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C NL G + C C GY K CVD++EC C
Sbjct: 122 VDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDIDECRY--RYC-QHR 176
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GSF C C PG++ ++ CVD++EC D A C RC N+ G+F C C G EL
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D SC DIDECS +S +C C N+ G + C C +GY Q
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGY-QLLATRLCQDIDECESGAH 292
Query: 296 RCQ--HSCVNTPGSYHC 310
+C +CVN G Y C
Sbjct: 293 QCSEAQTCVNFHGGYRC 309
Score = 124 bits (298), Expect = 1e-27
Identities = 84/262 (32%), Positives = 118/262 (45%), Gaps = 32/262 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+VNEC P C G +C N GG+ C P +++ + G+G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLC--LP--------------RSAAVINDLHGEGPP 97
Query: 177 HNTE-GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGM- 233
C PGY+ DD CVD+DECA CR + C N GS++C C G
Sbjct: 98 PPVPPAQHPNPCPPGYEPDDQDS-CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR 156
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
++ P+ C DIDEC C + C N G+++C C+ G+ Q +
Sbjct: 157 KIGPE---CVDIDECRYR--YCQH-RCVNLPGSFRCQCEPGF-QLGPNNRSCVDVNECDM 209
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C+ C N+ G++ C C +G+ L DG SC DIDEC+ + C +C N G ++C
Sbjct: 210 GAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRCVNEPGRFSCH 268
Query: 354 CTDGLVPSAAGAKPTCQDIDEC 375
C G A CQDIDEC
Sbjct: 269 CPQGY---QLLATRLCQDIDEC 287
Score = 120 bits (290), Expect = 1e-26
Identities = 102/328 (31%), Positives = 126/328 (38%), Gaps = 61/328 (18%)
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXX 286
EC G E PD C+D++EC C C N G Y C+ +S +
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL-----PRSAAVINDLH 92
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRN 345
QH PG + D SC D+DECA C Q C N
Sbjct: 93 GEGPPPPVPPAQHPNPCPPG----------YEPDDQDSCVDVDECAQALHDCRPSQDCHN 142
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
GSY CTC DG P C DI DE + C
Sbjct: 143 LPGSYQCTCPDGYRKIG----PECVDI---------------DECRY-------RYC-QH 175
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C N GSF CQC G+ + P +C D +EC++G C C N G+F CRC G
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNR-SCVDVNECDMGA-PCEQR--CFNSYGTFLCRCHQG 231
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
+ DG +C D+DEC ++ C R C N G F C C GY+ + C
Sbjct: 232 YELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQ--------LLATRLC 281
Query: 524 VDIDECANDPTLCENGH-CSNTPGGYEC 550
DIDEC + C C N GGY C
Sbjct: 282 QDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 114 bits (275), Expect = 7e-25
Identities = 63/148 (42%), Positives = 79/148 (53%), Gaps = 15/148 (10%)
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVD 477
CP GY +P+ +C D DEC DC P+ DC NLPGS+QC C DG+R G C D+D
Sbjct: 109 CPPGY--EPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDID 166
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC C R C N GSFRC C+ G++ G R SCVD++EC + CE
Sbjct: 167 ECRYRY--CQHR--CVNLPGSFRCQCEPGFQ-LGPNNR------SCVDVNEC-DMGAPCE 214
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
C N+ G + C C G+ DG SC
Sbjct: 215 Q-RCFNSYGTFLCRCHQGYELHRDGFSC 241
Score = 107 bits (258), Expect = 8e-23
Identities = 70/208 (33%), Positives = 94/208 (45%), Gaps = 33/208 (15%)
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
R C N PGSY CTC +G+ R G C DIDEC R C +C N GS+ C C
Sbjct: 135 RPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECR--YRYCQH-RCVNLPGSFRCQCE 189
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G +C D++EC D P C C N+ G+F+
Sbjct: 190 PGF--QLGPNNRSCVDVNEC-------------------DMGAP--CEQ-RCFNSYGTFL 225
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT-CE 474
C+C GY + + G +C+D DEC + C C+N PG F C C G++ C+
Sbjct: 226 CRCHQGYELHRD-GFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQLLATRLCQ 282
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCL 502
D+DEC + C TC N G +RC+
Sbjct: 283 DIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 73.3 bits (172), Expect = 2e-12
Identities = 39/106 (36%), Positives = 50/106 (47%), Gaps = 13/106 (12%)
Query: 462 CRDGWRGDGA-TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
C G+ D +C DVDEC C P C N GS++C C GY+ G
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGP-------- 160
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CVDIDEC C++ C N PG + C C+ GF + RSC+
Sbjct: 161 -ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCV 202
Score = 36.7 bits (81), Expect = 0.22
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRC 227
S+T C GY+ D S+ C D++EC C+G +C+N G + C
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
>BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein.
Length = 363
Score = 161 bits (390), Expect = 8e-39
Identities = 118/354 (33%), Positives = 155/354 (43%), Gaps = 48/354 (13%)
Query: 159 VDVNEC-EIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-- 215
VDV+EC E D D C NT S+ C C+PGYK + K C DIDEC +ND G
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGE--GKQCEDIDEC-ENDYYNGGCV 88
Query: 216 GRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+N G++RC C G LA D +C D+DEC +G C C N MG+Y+C C G+
Sbjct: 89 HECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGF 147
Query: 276 A----QSTVKSHXXXXXXXXXXXXRCQHSCVNTP-GSYHCTCREGWHLRADGRSCRDIDE 330
Q T C H C TP G C CR G+ L + + C
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLT-- 205
Query: 331 CAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
C G C C +T C C + G TC I+ CA + D
Sbjct: 206 CNYGNGGCQHS-CEDTDTGPMCGCHQKYALHSDGR--TC--IETCA-----VNNGGCDR- 254
Query: 391 QKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD 450
+C +T C CP G++++P+ G C D +EC + C
Sbjct: 255 ---------------TCKDTATGVRCSCPVGFTLQPD-GKTCKDINECLVNNGGCDHF-- 296
Query: 451 CINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
C N GSF+C CR G++ D TC+D+DEC H C N+ GSF+CL
Sbjct: 297 CRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDH---ICINSPGSFQCL 347
Score = 152 bits (368), Expect = 4e-36
Identities = 109/352 (30%), Positives = 157/352 (44%), Gaps = 45/352 (12%)
Query: 117 MEVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECE--IVDGVCGD 173
++V+EC+ C C+N + C C PGY+ + K C D++ECE +G C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQ--CEDIDECENDYYNGGCVH 89
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
+C N G++ C C G+ C+D+DEC DN+ C+ CVN GS+ C+C G
Sbjct: 90 -ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQ-QICVNAMGSYECQCHSGF 147
Query: 234 ELAPDRLSC----KDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
L+ ++ +C + C C++ E G C C G+ ++
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGF--DLAQNQKDCTLT 205
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGS 349
CQHSC +T C C + + L +DGR+C I+ CA C C++T
Sbjct: 206 CNYGNGGCQHSCEDTDTGPMCGCHQKYALHSDGRTC--IETCAVNNGGC-DRTCKDTATG 262
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
C+C G G TC+DI+EC L++ D C N
Sbjct: 263 VRCSCPVGFTLQPDG--KTCKDINEC--LVNN---GGCDHF----------------CRN 299
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECEL-GTCDCHPAADCINLPGSFQC 460
T+GSF C C GY + ++ C D DEC TCD H CIN PGSFQC
Sbjct: 300 TVGSFECGCRKGYKLLTDE-RTCQDIDECSFERTCD-H---ICINSPGSFQC 346
Score = 150 bits (364), Expect = 1e-35
Identities = 104/331 (31%), Positives = 146/331 (44%), Gaps = 41/331 (12%)
Query: 244 DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
D+DECS + C A C+N +Y+C+C GY + C H C+
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECI 92
Query: 303 NTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPS- 361
N PG+Y CTC +G+ L DG +C D+DEC C C N +GSY C C G S
Sbjct: 93 NIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGFFLSD 151
Query: 362 -------AAGAKPTCQDIDE-CADL--------ISTIIMMSVDELQKSVDPQIPELCGAG 405
+ C + D CA + ++ D Q D + G G
Sbjct: 152 NQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNG 211
Query: 406 ----SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR 461
SC +T +C C Y++ + G C + G CD C + +C
Sbjct: 212 GCQHSCEDTDTGPMCGCHQKYALHSD-GRTCIETCAVNNGGCD----RTCKDTATGVRCS 266
Query: 462 CRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C G+ + DG TC+D++ECL NNGGC C NT GSF C C GYK +
Sbjct: 267 CPVGFTLQPDGKTCKDINECLVNNGGCD--HFCRNTVGSFECGCRKGYK-------LLTD 317
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYEC 550
+C DIDEC+ + T C++ C N+PG ++C
Sbjct: 318 ERTCQDIDECSFERT-CDH-ICINSPGSFQC 346
Score = 111 bits (267), Expect = 6e-24
Identities = 54/139 (38%), Positives = 76/139 (54%), Gaps = 12/139 (8%)
Query: 430 PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTN--NGGCH 487
P D DEC GT DCH A C N P S++C C+ G++G+G CED+DEC + NGGC
Sbjct: 29 PGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCV 88
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGG 547
C N G++RC C G+ G ++C+D+DEC ++ C+ C N G
Sbjct: 89 HE--CINIPGNYRCTCFDGFMLAHDG-------HNCLDVDECQDNNGGCQQ-ICVNAMGS 138
Query: 548 YECDCDVGFTRAADGRSCL 566
YEC C GF + + +C+
Sbjct: 139 YECQCHSGFFLSDNQHTCI 157
Score = 107 bits (257), Expect = 1e-22
Identities = 60/162 (37%), Positives = 79/162 (48%), Gaps = 12/162 (7%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C NT S+ C C GY +G C D DECE + +CIN+PG+++C C DG+
Sbjct: 50 CQNTPKSYKCLCKPGYK---GEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGF 106
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
DG C DVDEC NNGGC + C N GS+ C C +G+ C++
Sbjct: 107 MLAHDGHNCLDVDECQDNNGGC--QQICVNAMGSYECQCHSGF---FLSDNQHTCIHRSN 161
Query: 525 DIDECANDPTLCENGHCSNTP-GGYECDCDVGFTRAADGRSC 565
+ C N C + C TP GG CDC GF A + + C
Sbjct: 162 EGMNCMNKDHGCAH-ICRETPKGGVACDCRPGFDLAQNQKDC 202
Score = 103 bits (247), Expect = 2e-21
Identities = 84/268 (31%), Positives = 111/268 (41%), Gaps = 40/268 (14%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTCTDGLV 359
C NTP SY C C+ G+ + +G+ C DIDEC G +C N G+Y CTC DG +
Sbjct: 50 CQNTPKSYKCLCKPGY--KGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFM 107
Query: 360 PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCP 419
+ G C D+DEC D QI C N +GS+ CQC
Sbjct: 108 LAHDGHN--CLDVDECQD-------------NNGGCQQI--------CVNAMGSYECQCH 144
Query: 420 DGYSVKPEQGPACTDDDECELGTCDCHPAAD-CINLP-GSFQCRCRDGWRGDGATCEDVD 477
G+ + Q +E H A C P G C CR G+ +
Sbjct: 145 SGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTL 204
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
C NGGC + +C +TD C C Y G RT C+ +C ++ D T
Sbjct: 205 TCNYGNGGC--QHSCEDTDTGPMCGCHQKYALHSDG-RT--CIETCA-VNNGGCDRT--- 255
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
C +T G C C VGFT DG++C
Sbjct: 256 ---CKDTATGVRCSCPVGFTLQPDGKTC 280
Score = 73.7 bits (173), Expect = 2e-12
Identities = 68/248 (27%), Positives = 97/248 (39%), Gaps = 46/248 (18%)
Query: 327 DIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
D+DEC+ G C C+NT SY C C P G C+DIDEC +
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCK----PGYKGEGKQCEDIDECEN-------- 80
Query: 386 SVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
D C C N G++ C C DG+ + + G C D DEC+ C
Sbjct: 81 --DYYNGG--------C-VHECINIPGNYRCTCFDGFMLAHD-GHNCLDVDECQDNNGGC 128
Query: 446 HPAADCINLPGSFQCRCRDGW--RGDGATC----EDVDECLTNNGGCHPRATCANTD-GS 498
C+N GS++C+C G+ + TC + C+ + GC C T G
Sbjct: 129 QQI--CVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGC--AHICRETPKGG 184
Query: 499 FRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTR 558
C C G+ C +C N C++ C +T G C C +
Sbjct: 185 VACDCRPGFD---LAQNQKDCTLTC----NYGNGG--CQHS-CEDTDTGPMCGCHQKYAL 234
Query: 559 AADGRSCL 566
+DGR+C+
Sbjct: 235 HSDGRTCI 242
>AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellular
matrix protein protein.
Length = 443
Score = 161 bits (390), Expect = 8e-39
Identities = 87/217 (40%), Positives = 110/217 (50%), Gaps = 11/217 (5%)
Query: 145 CFPGYEKDSKNHTCVDVNEC-EIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C PGYE D ++ +CVDV+EC + + DCHN GS+ C C GY+ CVDI
Sbjct: 109 CPPGYEPDDQD-SCVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYRK--IGPECVDI 165
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ RCVN GSFRC+C G +L P+ SC D++EC + G C N
Sbjct: 166 DECRYR--YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM--GAPCEQRCFNS 220
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
GT+ C C +GY CQ+ CVN PG + C C +G+ L A R
Sbjct: 221 YGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-R 279
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+DIDEC GA C Q C N G Y C T+ V
Sbjct: 280 LCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCV 316
Score = 136 bits (328), Expect = 3e-31
Identities = 102/319 (31%), Positives = 130/319 (40%), Gaps = 49/319 (15%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVD 202
+C GYE D + C DVNEC + C G+ C N G GY +C+
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYG--------GY-------LCLP 82
Query: 203 IDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECS-ITSGICSNGACE 261
ND G C G E D+ SC D+DEC+ + C
Sbjct: 83 RSAAVINDLHGEGPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDRRPSQDCH 141
Query: 262 NQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRAD 321
N G+YQC C +GY K CQH CVN PGS+ C C G+ L +
Sbjct: 142 NLSGSYQCTCPDGYR----KIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPN 197
Query: 322 GRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLIST 381
RSC D++EC GA PC +C N+ G++ C C G G +C DIDEC+
Sbjct: 198 NRSCVDVNECDMGA-PC-EQRCFNSYGTFLCRCHQGYELHRDGF--SCSDIDECS----- 248
Query: 382 IIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
LC C N G F C CP GY + + C D DECE G
Sbjct: 249 ---------------YSSYLC-QYRCVNEPGRFSCHCPQGYQLLATR--LCQDIDECESG 290
Query: 442 TCDCHPAADCINLPGSFQC 460
C A C+N G ++C
Sbjct: 291 AHQCSEAQTCVNFHGGYRC 309
Score = 131 bits (317), Expect = 6e-30
Identities = 88/264 (33%), Positives = 122/264 (46%), Gaps = 35/264 (13%)
Query: 305 PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGLVPSAA 363
P SY C +G+ D + CRD++EC C G +C N G Y C V +
Sbjct: 33 PDSY-TECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDL 91
Query: 364 GAK------PTCQDIDECA---DLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
+ P Q + C + + VDE +++ + P + CHN GS+
Sbjct: 92 HGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDRRP----SQDCHNLSGSY 147
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGAT 472
C CPDGY + GP C D DEC C H C+NLPGSF+C+C G++ + +
Sbjct: 148 QCTCPDGYR---KIGPECVDIDECRYRYCQ-H---RCVNLPGSFRCQCEPGFQLGPNNRS 200
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C DV+EC C R C N+ G+F C C GY+ G +SC DIDEC+
Sbjct: 201 CVDVNEC-DMGAPCEQR--CFNSYGTFLCRCHQGYELHRDG-------FSCSDIDECSYS 250
Query: 533 PTLCENGHCSNTPGGYECDCDVGF 556
LC+ C N PG + C C G+
Sbjct: 251 SYLCQY-RCVNEPGRFSCHCPQGY 273
Score = 124 bits (300), Expect = 6e-28
Identities = 73/197 (37%), Positives = 94/197 (47%), Gaps = 12/197 (6%)
Query: 117 MEVNECA-AFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA A C NL G + C C GY K CVD++EC C
Sbjct: 122 VDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYRKIGPE--CVDIDECRY--RYC-QHR 176
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GSF C C PG++ ++ CVD++EC D A C RC N+ G+F C C G EL
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D SC DIDECS +S +C C N+ G + C C +GY Q
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGY-QLLATRLCQDIDECESGAH 292
Query: 296 RCQ--HSCVNTPGSYHC 310
+C +CVN G Y C
Sbjct: 293 QCSEAQTCVNFHGGYRC 309
Score = 120 bits (288), Expect = 2e-26
Identities = 83/262 (31%), Positives = 118/262 (45%), Gaps = 32/262 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+VNEC P C G +C N GG+ C P +++ + G+G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLC--LP--------------RSAAVINDLHGEGPP 97
Query: 177 HNTE-GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGM- 233
C PGY+ DD CVD+DECA R + C N +GS++C C G
Sbjct: 98 PPVPPAQHPNPCPPGYEPDDQDS-CVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYR 156
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
++ P+ C DIDEC C + C N G+++C C+ G+ Q +
Sbjct: 157 KIGPE---CVDIDECRYR--YCQH-RCVNLPGSFRCQCEPGF-QLGPNNRSCVDVNECDM 209
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C+ C N+ G++ C C +G+ L DG SC DIDEC+ + C +C N G ++C
Sbjct: 210 GAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRCVNEPGRFSCH 268
Query: 354 CTDGLVPSAAGAKPTCQDIDEC 375
C G A CQDIDEC
Sbjct: 269 CPQGY---QLLATRLCQDIDEC 287
Score = 116 bits (278), Expect = 3e-25
Identities = 101/328 (30%), Positives = 125/328 (38%), Gaps = 61/328 (18%)
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXX 286
EC G E PD C+D++EC C C N G Y C+ +S +
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL-----PRSAAVINDLH 92
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRN 345
QH PG + D SC D+DECA Q C N
Sbjct: 93 GEGPPPPVPPAQHPNPCPPG----------YEPDDQDSCVDVDECAQALHDRRPSQDCHN 142
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
GSY CTC DG P C DI DE + C
Sbjct: 143 LSGSYQCTCPDGYRKIG----PECVDI---------------DECRY-------RYC-QH 175
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C N GSF CQC G+ + P +C D +EC++G C C N G+F CRC G
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNR-SCVDVNECDMGA-PCEQR--CFNSYGTFLCRCHQG 231
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
+ DG +C D+DEC ++ C R C N G F C C GY+ + C
Sbjct: 232 YELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQ--------LLATRLC 281
Query: 524 VDIDECANDPTLCENGH-CSNTPGGYEC 550
DIDEC + C C N GGY C
Sbjct: 282 QDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 106 bits (255), Expect = 2e-22
Identities = 61/148 (41%), Positives = 77/148 (52%), Gaps = 15/148 (10%)
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVD 477
CP GY +P+ +C D DEC D P+ DC NL GS+QC C DG+R G C D+D
Sbjct: 109 CPPGY--EPDDQDSCVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYRKIGPECVDID 166
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC C R C N GSFRC C+ G++ G R SCVD++EC + CE
Sbjct: 167 ECRYRY--CQHR--CVNLPGSFRCQCEPGFQ-LGPNNR------SCVDVNEC-DMGAPCE 214
Query: 538 NGHCSNTPGGYECDCDVGFTRAADGRSC 565
C N+ G + C C G+ DG SC
Sbjct: 215 Q-RCFNSYGTFLCRCHQGYELHRDGFSC 241
Score = 105 bits (251), Expect = 6e-22
Identities = 91/324 (28%), Positives = 128/324 (39%), Gaps = 51/324 (15%)
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
S+T C GY+ D S+ C D++EC C+G +C +G L R
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKG--------EMKCINHYGGYLCLPR-- 83
Query: 242 CKDIDECSITSGICSNGACEN-QMGTYQCVCDEGYAQSTVKSHXXXXX-XXXXXXXRCQH 299
++ + + G + C GY S R
Sbjct: 84 -----SAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDRRPSQ 138
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C N GSY CTC +G+ R G C DIDEC R C +C N GS+ C C G
Sbjct: 139 DCHNLSGSYQCTCPDGY--RKIGPECVDIDECR--YRYCQH-RCVNLPGSFRCQCEPGF- 192
Query: 360 PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCP 419
+C D++EC D P C C N+ G+F+C+C
Sbjct: 193 -QLGPNNRSCVDVNEC-------------------DMGAP--CEQ-RCFNSYGTFLCRCH 229
Query: 420 DGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT-CEDVDE 478
GY + + G +C+D DEC + C C+N PG F C C G++ C+D+DE
Sbjct: 230 QGYELHRD-GFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQLLATRLCQDIDE 286
Query: 479 CLTNNGGCHPRATCANTDGSFRCL 502
C + C TC N G +RC+
Sbjct: 287 CESGAHQCSEAQTCVNFHGGYRCV 310
Score = 68.9 bits (161), Expect = 4e-11
Identities = 38/106 (35%), Positives = 49/106 (46%), Gaps = 13/106 (12%)
Query: 462 CRDGWRGDGA-TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
C G+ D +C DVDEC P C N GS++C C GY+ G
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYRKIGP-------- 160
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CVDIDEC C++ C N PG + C C+ GF + RSC+
Sbjct: 161 -ECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCV 202
>AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming growth
factor-beta binding protein 4 protein.
Length = 669
Score = 159 bits (387), Expect = 2e-38
Identities = 80/200 (40%), Positives = 100/200 (50%), Gaps = 6/200 (3%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDS-KNHTCVDVNECEIVDGVCGDGD 175
+V+EC++ CG HG C N G F C C PGY S + C DVNEC D G+
Sbjct: 57 DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGE 116
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C NT+GSF C C PGY+ C+D+DEC++ D LC+ G C NT GSF C C G
Sbjct: 117 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED-LCQSGICTNTDGSFECICPPGHRA 175
Query: 236 APDRLSCKDIDECSITS-GICSNGACENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXX 292
PD SC D+DEC +C + CEN G+Y+CV CD GY +
Sbjct: 176 GPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETL 235
Query: 293 XXXRCQHSCVNTPGSYHCTC 312
C N GS+ C C
Sbjct: 236 QGVCGAALCENVEGSFLCVC 255
Score = 149 bits (362), Expect = 2e-35
Identities = 96/258 (37%), Positives = 120/258 (46%), Gaps = 40/258 (15%)
Query: 301 CVNTPGSYHC-TCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTCTDGL 358
CVN+PGS+ C C G HL GR C D+DEC+ GA PCG G C NT GS+ C+C G
Sbjct: 32 CVNSPGSFQCRACPSGHHLHR-GR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY 89
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
+ +G C D++EC + D P G C NT GSF C C
Sbjct: 90 -RAPSGRPGPCADVNECLE----------------GDFCFPH----GECLNTDGSFACTC 128
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDV 476
GY P +G +C D DEC D + C N GSF+C C G R D A+C DV
Sbjct: 129 APGYRPGP-RGASCLDVDECSEE--DLCQSGICTNTDGSFECICPPGHRAGPDLASCLDV 185
Query: 477 DECLTNNGGCHPRATCANTDGSFRCL--CDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
DEC C N+ GS+RC+ CD GY G +C D++EC
Sbjct: 186 DECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG--------TCDDVNECETLQG 237
Query: 535 LCENGHCSNTPGGYECDC 552
+C C N G + C C
Sbjct: 238 VCGAALCENVEGSFLCVC 255
Score = 147 bits (357), Expect = 8e-35
Identities = 94/269 (34%), Positives = 125/269 (46%), Gaps = 35/269 (13%)
Query: 242 CKDIDECSITSGICSNGACENQMGTYQC-VCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
C+D+DEC C C N G++QC C G+ +
Sbjct: 15 CEDVDECE-NHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGH 73
Query: 301 CVNTPGSYHCTCREGWHLRADGRS--CRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL 358
C NT GS+ C+C G+ + GR C D++EC G G+C NT GS+ CTC G
Sbjct: 74 CTNTEGSFRCSCAPGYRAPS-GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY 132
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
P GA +C D+DEC++ +LC +G C NT GSF C C
Sbjct: 133 RPGPRGA--SCLDVDECSE---------------------EDLCQSGICTNTDGSFECIC 169
Query: 419 PDGYSVKPEQGPACTDDDEC-ELGTCDCHPAADCINLPGSFQC--RCRDGWR-GDGATCE 474
P G+ P+ +C D DEC E G C + C N PGS++C C G+ G TC+
Sbjct: 170 PPGHRAGPDLA-SCLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEGTCD 227
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLC 503
DV+EC T G C A C N +GSF C+C
Sbjct: 228 DVNECETLQGVC-GAALCENVEGSFLCVC 255
Score = 144 bits (350), Expect = 6e-34
Identities = 93/280 (33%), Positives = 119/280 (42%), Gaps = 34/280 (12%)
Query: 148 GYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCH-CRPGYKADDFSKICVDIDEC 206
G++ ++ C DV+ECE C +C N+ GSF C C G+ C D+DEC
Sbjct: 5 GFQPNAAGSECEDVDECE-NHLACPGQECVNSPGSFQCRACPSGHHL--HRGRCTDVDEC 61
Query: 207 ADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRLS-CKDIDECSITSGICSNGACENQM 264
+ C G C NT GSFRC C G R C D++EC +G C N
Sbjct: 62 SSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTD 121
Query: 265 GTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGR 323
G++ C C GY + CQ C NT GS+ C C G D
Sbjct: 122 GSFACTCAPGYRPGP-RGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLA 180
Query: 324 SCRDIDEC-AGGARPCGGGQCRNTVGSYTCT--CTDGLVPSAAGAKPTCQDIDECADLIS 380
SC D+DEC G CG +C N+ GSY C C G AG + TC D++EC L
Sbjct: 181 SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGY---HAGPEGTCDDVNECETL-- 235
Query: 381 TIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD 420
+CGA C N GSF+C CP+
Sbjct: 236 ------------------QGVCGAALCENVEGSFLCVCPN 257
Score = 136 bits (329), Expect = 2e-31
Identities = 81/214 (37%), Positives = 107/214 (50%), Gaps = 39/214 (18%)
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G P+AAG++ C+D+DEC + ++ C C N+ GSF C
Sbjct: 5 GFQPNAAGSE--CEDVDECENHLA---------------------CPGQECVNSPGSFQC 41
Query: 417 Q-CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR---GDGAT 472
+ CP G+ + +G CTD DEC G C P C N GSF+C C G+R G
Sbjct: 42 RACPSGHHL--HRG-RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP 98
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C DV+ECL + C P C NTDGSF C C GY+ G SC+D+DEC+ +
Sbjct: 99 CADVNECLEGDF-CFPHGECLNTDGSFACTCAPGYRPGPRGA-------SCLDVDECSEE 150
Query: 533 PTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
LC++G C+NT G +EC C G D SCL
Sbjct: 151 D-LCQSGICTNTDGSFECICPPGHRAGPDLASCL 183
Score = 87.0 bits (206), Expect = 2e-16
Identities = 45/121 (37%), Positives = 60/121 (49%), Gaps = 5/121 (4%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC-EIVDGVCGDGD 175
++V+EC+ LC G C N G F C C PG+ +C+DV+EC E +CG
Sbjct: 142 LDVDECSE-EDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQR 200
Query: 176 CHNTEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C N+ GS+ C C PGY A C D++EC +C C N GSF C C +
Sbjct: 201 CENSPGSYRCVRDCDPGYHAGP-EGTCDDVNECETLQGVCGAALCENVEGSFLCVCPNSP 259
Query: 234 E 234
E
Sbjct: 260 E 260
Score = 85.4 bits (202), Expect = 5e-16
Identities = 42/113 (37%), Positives = 58/113 (51%), Gaps = 5/113 (4%)
Query: 160 DVNECEIV-DGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC 218
DV+EC++ D VC G C NT ++C+C GY C+D DECAD + C GGRC
Sbjct: 390 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 449
Query: 219 VNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVC 271
VNT GS+ C C + L + C + S+ + G C ++G VC
Sbjct: 450 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL---GVCWQEVGA-DLVC 498
Score = 72.9 bits (171), Expect = 3e-12
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 202 DIDECA-DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGAC 260
D+DEC D +C+ G CVNTA + C C +G RL C D DEC+ C G C
Sbjct: 390 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 449
Query: 261 ENQMGTYQCVCD 272
N +G+Y C C+
Sbjct: 450 VNTVGSYHCTCE 461
Score = 66.9 bits (156), Expect = 2e-10
Identities = 29/59 (49%), Positives = 32/59 (54%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
CVNT Y C C G++ C D DECA C GG+C NTVGSY CTC LV
Sbjct: 407 CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLV 465
Score = 66.5 bits (155), Expect = 2e-10
Identities = 40/119 (33%), Positives = 50/119 (42%), Gaps = 6/119 (5%)
Query: 213 CRGGRCVNT-AGSFRCECGHGME-LAP--DRLSCKDIDECSI-TSGICSNGACENQMGTY 267
CR +C T ++ C HG LAP D +D+DEC + +C +G C N Y
Sbjct: 355 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 414
Query: 268 QCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSC 325
C C GY T + C+ CVNT GSYHCTC L R C
Sbjct: 415 SCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 473
Score = 64.9 bits (151), Expect = 7e-10
Identities = 37/115 (32%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 118 EVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC F +C G C N G++C C GY ++ C+D +EC + C G C
Sbjct: 390 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 449
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
NT GS+ C C P D + CV + + +D L G C G+ C H
Sbjct: 450 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL---GVCWQEVGA-DLVCSH 500
Score = 64.5 bits (150), Expect = 1e-09
Identities = 33/99 (33%), Positives = 42/99 (42%), Gaps = 7/99 (7%)
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
GD + DVDEC C NT + C C GY Y + + C+D D
Sbjct: 383 GDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY---YHTQRL----ECIDND 435
Query: 528 ECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
ECA++ CE G C NT G Y C C+ R C+
Sbjct: 436 ECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 474
Score = 50.4 bits (115), Expect = 2e-05
Identities = 34/121 (28%), Positives = 43/121 (35%), Gaps = 6/121 (4%)
Query: 402 CGAGSCHNT-IGSFVCQCPDGYSVKPEQGPACT--DDDECELGTCDCHPAADCINLPGSF 458
C C T + CP G G D DEC+L + C+N +
Sbjct: 355 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 414
Query: 459 QCRCRDG--WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
C C +G + C D DEC C C NT GS+ C C+ DG R
Sbjct: 415 SCYCSNGYYYHTQRLECIDNDECADEEPACE-GGRCVNTVGSYHCTCEPPLVLDGSQRRC 473
Query: 517 V 517
V
Sbjct: 474 V 474
Score = 47.6 bits (108), Expect = 1e-04
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 6/85 (7%)
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCH 446
VDE Q D ++C +G C NT + C C +GY Q C D+DEC C
Sbjct: 391 VDECQLFRD----QVCKSGVCVNTAPGYSCYCSNGYYYH-TQRLECIDNDECADEEPACE 445
Query: 447 PAADCINLPGSFQCRCRDGWRGDGA 471
C+N GS+ C C DG+
Sbjct: 446 -GGRCVNTVGSYHCTCEPPLVLDGS 469
Score = 44.0 bits (99), Expect = 0.001
Identities = 37/131 (28%), Positives = 52/131 (39%), Gaps = 26/131 (19%)
Query: 326 RDIDECA-GGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIM 384
RD+DEC + C G C NT Y+C C++G + C D DECAD
Sbjct: 389 RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHT--QRLECIDNDECAD------- 439
Query: 385 MSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC---ELG 441
+P C G C NT+GS+ C C + Q +++ + LG
Sbjct: 440 ---------EEP----ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLG 486
Query: 442 TCDCHPAADCI 452
C AD +
Sbjct: 487 VCWQEVGADLV 497
Score = 36.3 bits (80), Expect = 0.29
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 2/44 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQ-RCEPCPKKGTDAYQNLC 48
C L +V CCC+ +G+ WG+ R + CP T YQ+LC
Sbjct: 330 CDNILARNVTWQECCCT-VGEGWGSGCRIQQCPGTETAEYQSLC 372
Score = 34.3 bits (75), Expect = 1.2
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Query: 6 CSGP-LPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIAVGTLLPP 57
CS P L CCC G+AWG C CP + +D ++ LC L PP
Sbjct: 498 CSHPRLDRQATYTECCC-LYGEAWG-MDCALCPAQDSDDFEALC---NVLRPP 545
>BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein.
Length = 647
Score = 158 bits (383), Expect = 6e-38
Identities = 143/464 (30%), Positives = 194/464 (41%), Gaps = 71/464 (15%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV-DVNECEIVDGVCGDG-DCHNT 179
C+A P + G G C C C PG+E H C DVNEC G C G CHNT
Sbjct: 160 CSANPCVNG-GVCLATYPQIQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNT 214
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCV---NTAGSFR-CECGHGMEL 235
GSF C C G + + + C GG C +F C C G +
Sbjct: 215 LGSFQCLCPVGQEGP---RCELRAGPCPPRGC-SNGGTCQLMPEKDSTFHLCLCPPGF-I 269
Query: 236 APDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
PD C +++ + S C NG C++ + TY C+C E +
Sbjct: 270 GPD---C-EVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPH 325
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCGGGQCRNTVGSYTCT 353
R +C N+ GS+HC C GW G SC + +D+C A G C + VGS++C
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIA-ATCAPGSTCIDRVGSFSCL 380
Query: 354 CTDGLVPSAAGAKPTCQDID-----ECAD---LISTIIMM----SVDELQKSVDP----- 396
C G + C +C+ ST+ + S + +D
Sbjct: 381 CPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQ 440
Query: 397 QIPELCG-AGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINL 454
Q P C GSC NT GSF C CP GY+ G C D +EC + CHP + C++L
Sbjct: 441 QGPSPCEHGGSCLNTPGSFNCLCPPGYT-----GSRCEADHNECL--SQPCHPGSTCLDL 493
Query: 455 PGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
+F C C G +G CE + +EC + C A C + F+C+C G+ G
Sbjct: 494 LATFHCLCPPGL--EGQLCEVETNECAS--APCLNHADCHDLLNGFQCICLPGFSG---- 545
Query: 514 LRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVGF 556
T C DIDEC + P C NG C + PG + C C GF
Sbjct: 546 --TRCEE----DIDECRSSP--CANGGQCQDQPGAFHCKCLPGF 581
Score = 155 bits (377), Expect = 3e-37
Identities = 129/421 (30%), Positives = 184/421 (43%), Gaps = 63/421 (14%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV----------DVNECEIVDGVC 171
C G C C N G TC P EKDS H C+ +VN V C
Sbjct: 231 CELRAGPCPPRGCSN---GGTCQLMP--EKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 285
Query: 172 GDGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDEC-ADNDALCR-GGRCVNTAGSFRCE 228
+G C + ++TC C + D S+ D+DEC CR GG C N+AGSF C
Sbjct: 286 QNGGTCQDGLDTYTCLCPETWTGWDCSE---DVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 229 CGHGMELAPDRLSCKD-IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXX 286
C G SC++ +D+C + C+ G+ C +++G++ C+C G ++ + H
Sbjct: 343 CVSGW----GGTSCEENLDDC--IAATCAPGSTCIDRVGSFSCLCPPG--RTGLLCHLED 394
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECA---GGARPCG-GG 341
Q S GS C C+ G+ G +C +D+DEC G PC GG
Sbjct: 395 MCLSQPCHGDAQCSTNPLTGSTLCLCQPGY----SGPTCHQDLDECLMAQQGPSPCEHGG 450
Query: 342 QCRNTVGSYTCTCTDGLVPSAAGA------KPTCQDIDECADLISTIIMMSVDELQKSV- 394
C NT GS+ C C G S A C C DL++T + L+ +
Sbjct: 451 SCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLC 510
Query: 395 DPQIPELCGA-----GSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
+ + E A CH+ + F C C G+S G C +D DEC + C
Sbjct: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFS-----GTRCEEDIDECR--SSPCANG 563
Query: 449 ADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
C + PG+F C+C G+ G E VDECL++ C A+C + G+F CLC +G+
Sbjct: 564 GQCQDQPGAFHCKCLPGFEGPRCQTE-VDECLSDP--CPVGASCLDLPGAFFCLCPSGFT 620
Query: 509 G 509
G
Sbjct: 621 G 621
Score = 140 bits (340), Expect = 9e-33
Identities = 129/450 (28%), Positives = 177/450 (39%), Gaps = 82/450 (18%)
Query: 137 LLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDCH-NTEGSFTCHCRPGYKAD 194
L F C C PG+ + C E C G CH G C C PG+ +
Sbjct: 97 LTPSFLCTCLPGFTGER----CQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGE 152
Query: 195 DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGI 254
C D C+ N + GG C+ T +C C G E +D++EC G
Sbjct: 153 Q----CQLRDFCSANPCV-NGGVCLATYPQIQCHCPPGFE---GHACERDVNECFQDPGP 204
Query: 255 CSNG-ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYH-CTC 312
C G +C N +G++QC+C G + ++H C C
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 313 REGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ 370
G+ G C + D C + C GG C++ + +YTC C P +
Sbjct: 265 PPGFI----GPDCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLC-----PETWTGWDCSE 313
Query: 371 DIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQG 429
D+DEC + Q P C G+C N+ GSF C C G+ G
Sbjct: 314 DVDEC-------------------ETQGPPHCRNGGTCQNSAGSFHCVCVSGWG-----G 349
Query: 430 PACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHP 488
+C ++ D+C TC P + CI+ GSF C C G G C D CL+ CH
Sbjct: 350 TSCEENLDDCIAATCA--PGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLSQP--CHG 403
Query: 489 RATCANTD--GSFRCLCDTGYKGDGYGLRTVCCVYSC-VDIDECA---NDPTLCENG-HC 541
A C+ GS CLC GY G +C D+DEC P+ CE+G C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGP-----------TCHQDLDECLMAQQGPSPCEHGGSC 452
Query: 542 SNTPGGYECDCDVGFTRA---ADGRSCLGK 568
NTPG + C C G+T + AD CL +
Sbjct: 453 LNTPGSFNCLCPPGYTGSRCEADHNECLSQ 482
Score = 135 bits (326), Expect = 5e-31
Identities = 131/448 (29%), Positives = 175/448 (39%), Gaps = 78/448 (17%)
Query: 126 PGLCG-HGRCRNLLGGFT-CDCFPGY--EKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
P C GRC G C C PG+ E+ C N C V+G G C T
Sbjct: 124 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-SANPC--VNG----GVCLATYP 176
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRL 240
CHC PG++ + D++EC + C +G C NT GSF+C C G E L
Sbjct: 177 QIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCEL 233
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH- 299
++G E + C+C G+ + + +CQ+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSH-----QCQNG 288
Query: 300 -SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARP-C-GGGQCRNTVGSYTCTCT 355
+C + +Y C C E W G C D+DEC P C GG C+N+ GS+ C C
Sbjct: 289 GTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSF 414
G G +++D+C I C GS C + +GSF
Sbjct: 345 SGW-----GGTSCEENLDDC----------------------IAATCAPGSTCIDRVGSF 377
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP--GSFQCRCRDGWRGDGAT 472
C CP G + G C +D C + CH A C P GS C C+ G+ G T
Sbjct: 378 SCLCPPGRT-----GLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLCQPGY--SGPT 428
Query: 473 C-EDVDECLTNNGG---CHPRATCANTDGSFRCLCDTGYKGDGYGL-RTVCCVYSCVDID 527
C +D+DECL G C +C NT GSF CLC GY G C C
Sbjct: 429 CHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488
Query: 528 ECANDPTLCENGHCSNTPG--GYECDCD 553
C + L HC PG G C+ +
Sbjct: 489 TCLD---LLATFHCLCPPGLEGQLCEVE 513
Score = 111 bits (267), Expect = 6e-24
Identities = 118/414 (28%), Positives = 161/414 (38%), Gaps = 67/414 (16%)
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNT--------------AGSF 225
G TC C PG+ + C D C N LC+ GG C SF
Sbjct: 47 GQGTCQCAPGF----LGETCQFPDPC-QNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSF 101
Query: 226 RCECGHGMELAPDRLSCKDIDECSITSGICSN-GACENQM-GTYQCVCDEGYAQSTVKSH 283
C C G +R K D C CS G C Q G QC C G+ +
Sbjct: 102 LCTCLPGF--TGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR 157
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGG- 341
C+ T C C G+ +G +C RD++EC PC G
Sbjct: 158 DFCSANPCVNGG----VCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGT 209
Query: 342 QCRNTVGSYTCTCTDGLV-PSA---AGAKP--------TCQDIDECADLISTIIM---MS 386
C NT+GS+ C C G P AG P TCQ + E +
Sbjct: 210 SCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Query: 387 VDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECEL-GTC 443
+ + + D + C G+C + + ++ C CP+ ++ G C++D DECE G
Sbjct: 270 GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT-----GWDCSEDVDECETQGPP 324
Query: 444 DCHPAADCINLPGSFQCRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCL 502
C C N GSF C C GW G +CE+ +D+C+ C P +TC + GSF CL
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLDDCIAAT--CAPGSTCIDRVGSFSCL 380
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG--GYECDCDV 554
C G G L +C C +C+ +P L + C PG G C D+
Sbjct: 381 CPPGRTGLLCHLEDMCLSQPCHGDAQCSTNP-LTGSTLCLCQPGYSGPTCHQDL 433
Score = 75.4 bits (177), Expect = 5e-13
Identities = 46/139 (33%), Positives = 68/139 (48%), Gaps = 10/139 (7%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++E NECA+ P L H C +LL GF C C PG+ S D++EC G G
Sbjct: 511 EVETNECASAPCL-NHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRSSPCANG-GQ 565
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C + G+F C C PG++ + ++DEC +D G C++ G+F C C G
Sbjct: 566 CQDQPGAFHCKCLPGFEG---PRCQTEVDECL-SDPCPVGASCLDLPGAFFCLCPSGFTG 621
Query: 236 APDRLSCKDIDECSITSGI 254
+ R K++ E I G+
Sbjct: 622 SQGR-HWKELAEYFIPFGL 639
Score = 72.1 bits (169), Expect = 5e-12
Identities = 70/253 (27%), Positives = 98/253 (38%), Gaps = 34/253 (13%)
Query: 331 CAGGARPCG-GGQCRN-TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
C PC GG C + ++G TC C G + CQ+ C + S ++
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
Query: 389 -ELQKSVDPQIPE-LCGAGSCHNTIGSFVCQ------CPDGY-------SVKPEQGPACT 433
L S P P LC +C CQ CP + ++ P C+
Sbjct: 88 LGLPSSPSPLTPSFLC---TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCS 144
Query: 434 -----DDDECEL-GTCDCHPAAD---CINLPGSFQCRCRDGWRGDGATCE-DVDECLTNN 483
++C+L C +P + C+ QC C G+ +G CE DV+EC +
Sbjct: 145 CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF--EGHACERDVNECFQDP 202
Query: 484 GGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT-VCCVYSCVDIDECANDPTLCENGH-C 541
G C +C NT GSF+CLC G +G LR C C + C P H C
Sbjct: 203 GPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLC 262
Query: 542 SNTPGGYECDCDV 554
PG DC+V
Sbjct: 263 LCPPGFIGPDCEV 275
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 155 bits (376), Expect = 4e-37
Identities = 144/463 (31%), Positives = 193/463 (41%), Gaps = 95/463 (20%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC PG C G C N LG F C C G E CE+ G C
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGP----------RCELRAGPCPPR 241
Query: 175 DCHN---------TEGSF-TCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGS 224
C N + +F C C PG+ D V+ D C + GG C + +
Sbjct: 242 GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---VNPDNCVSHQCQ-NGGTCQDGLDT 297
Query: 225 FRCECGHGMELAPDRLSCKDIDECSITSG--ICSN-GACENQMGTYQCVCDEGYAQSTVK 281
+ C C E +D+DEC T G C N G C+N G++ CVC G+ ++ +
Sbjct: 298 YTCLC---PETWTGWDCSEDVDECE-TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE 353
Query: 282 SHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GG 340
+ +C++ GS+ C C G G C D C ++PC G
Sbjct: 354 ENLDDCIAATCAPG---STCIDRVGSFSCLCPPG----RTGLLCHLEDMCL--SQPCHGD 404
Query: 341 GQCRNT--VGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDELQKSVDPQ 397
QC GS C C G + PTC QD+DEC +M+ Q
Sbjct: 405 AQCSTNPLTGSTLCLCQPGY------SGPTCHQDLDEC--------LMA---------QQ 441
Query: 398 IPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLP 455
P C GSC NT GSF C CP GY+ G C D +EC + CHP + C++L
Sbjct: 442 GPSPCEHGGSCLNTPGSFNCLCPPGYT-----GSRCEADHNECL--SQPCHPGSTCLDLL 494
Query: 456 GSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+F C C G +G CE + +EC + C A C + F+C+C G+ G
Sbjct: 495 ATFHCLCPPGL--EGQLCEVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSG----- 545
Query: 515 RTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
T C DIDEC + P C N G C + PG + C C GF
Sbjct: 546 -TRC----EEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF 581
Score = 145 bits (351), Expect = 4e-34
Identities = 135/465 (29%), Positives = 192/465 (41%), Gaps = 70/465 (15%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGV-CGDGD-CHNTEGSFTCHCRP 189
G C++ L +TC C P E + DV+ECE C +G C N+ GSF C C
Sbjct: 289 GTCQDGLDTYTCLC-P--ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVS 345
Query: 190 GYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC 248
G+ + ++D+C A C G C++ GSF C C G L C D C
Sbjct: 346 GWGGTSCEE---NLDDCIA--ATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC 396
Query: 249 SITSGICSNGACENQ--MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SCVNT 304
++ + C G+ C+C GY+ T C+H SC+NT
Sbjct: 397 -LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 305 PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTCTDGL---- 358
PGS++C C G+ G C D +EC ++PC G C + + ++ C C GL
Sbjct: 456 PGSFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPGLEGQL 509
Query: 359 --VPSAAGAKPTCQDIDECADLISTIIMM-----SVDELQKSVDPQIPELCG-AGSCHNT 410
V + A C + +C DL++ + S ++ +D C G C +
Sbjct: 510 CEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQ 569
Query: 411 IGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
G+F C+C G+ +GP C T+ DEC C A C++LPG+F C C G+ G
Sbjct: 570 PGAFHCKCLPGF-----EGPRCQTEVDECLSDPCPV--GASCLDLPGAFFCLCPSGFTGQ 622
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY------SC 523
CE V C N C P+ C + CLC G G C + SC
Sbjct: 623 --LCE-VPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 524 V-DI----DECANDPTLC------ENGHCSNTPGGYECDCDVGFT 557
V D+ EC + C G C P GY C C G+T
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 722
Score = 139 bits (336), Expect = 3e-32
Identities = 128/464 (27%), Positives = 181/464 (39%), Gaps = 75/464 (16%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++E NECA+ P L H C +LL GF C C PG+ S D++EC G G
Sbjct: 511 EVETNECASAPCL-NHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRSSPCANG-GQ 565
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME- 234
C + G+F C C PG++ + ++DEC +D G C++ G+F C C G
Sbjct: 566 CQDQPGAFHCKCLPGFEG---PRCQTEVDECL-SDPCPVGASCLDLPGAFFCLCPSGFTG 621
Query: 235 -------LAPDRLSCKDI--DECSITSGICSNGACENQMGTYQCVCDEGYAQSTV----- 280
AP+ K I D+ + +C +G+ C C G+ Q +
Sbjct: 622 QLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDV 681
Query: 281 --KSHXXXXXXXXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGA 335
C H +C P Y+CTC G+ G +C ++ C G
Sbjct: 682 GWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSG- 736
Query: 336 RPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV 394
PC GG C + G Y CTC PS G P C Q S
Sbjct: 737 -PCLNGGSCNPSPGGYYCTCP----PSHTG--PQC---------------------QTST 768
Query: 395 DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCIN 453
D + C G+C N G+F C C G+ QGP C C A C +
Sbjct: 769 DYCVSAPCFNGGTCVNRPGTFSCLCAMGF-----QGPRCEGKLRPSCADSPCRNRATCQD 823
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
P +C C G+ G +C+ + + L C + C T SF CLC G+ G
Sbjct: 824 SPQGPRCLCPTGY--TGGSCQTLMD-LCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCN 880
Query: 514 LRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
L C + + + + +LC NG C ++ Y C C GF
Sbjct: 881 LPLSSCQKAA--LSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922
Score = 136 bits (330), Expect = 1e-31
Identities = 128/457 (28%), Positives = 179/457 (39%), Gaps = 72/457 (15%)
Query: 130 GHGRCRN--LLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVD---GVCGDG-DCHNTEGS 182
G +C L G C C PGY TC D++EC + C G C NT GS
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGS 458
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLS 241
F C C PGY S+ D +EC C G C++ +F C C G+E +L
Sbjct: 459 FNCLCPPGYTG---SRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE---GQLC 510
Query: 242 CKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+ +EC+ S C N A C + + +QC+C G++ + +
Sbjct: 511 EVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG---Q 565
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C + PG++HC C G+ +G C+ ++DEC P G C + G++ C C G
Sbjct: 566 CQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGAS-CLDLPGAFFCLCPSGFT 620
Query: 360 PSAAG----AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
A CQ C D + D P+ C G C +
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---- 676
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD---CINLPGSFQCRCRDGWRGDGAT 472
C C G++ GP C E ELG C P A C P + C C G+ G T
Sbjct: 677 CVCDVGWT-----GPEC----EAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGP--T 725
Query: 473 C-EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
C E++ C ++G C +C + G + C C + G T CV + C N
Sbjct: 726 CSEEMTAC--HSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA-----PCFN 778
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
G C N PG + C C +GF G C GK
Sbjct: 779 ------GGTCVNRPGTFSCLCAMGF----QGPRCEGK 805
Score = 135 bits (326), Expect = 5e-31
Identities = 131/448 (29%), Positives = 175/448 (39%), Gaps = 78/448 (17%)
Query: 126 PGLCG-HGRCRNLLGGFT-CDCFPGY--EKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
P C GRC G C C PG+ E+ C N C V+G G C T
Sbjct: 124 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-SANPC--VNG----GVCLATYP 176
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRL 240
CHC PG++ + D++EC + C +G C NT GSF+C C G E L
Sbjct: 177 QIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCEL 233
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH- 299
++G E + C+C G+ + + +CQ+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSH-----QCQNG 288
Query: 300 -SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARP-C-GGGQCRNTVGSYTCTCT 355
+C + +Y C C E W G C D+DEC P C GG C+N+ GS+ C C
Sbjct: 289 GTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSF 414
G G +++D+C I C GS C + +GSF
Sbjct: 345 SGW-----GGTSCEENLDDC----------------------IAATCAPGSTCIDRVGSF 377
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP--GSFQCRCRDGWRGDGAT 472
C CP G + G C +D C + CH A C P GS C C+ G+ G T
Sbjct: 378 SCLCPPGRT-----GLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLCQPGY--SGPT 428
Query: 473 C-EDVDECLTNNGG---CHPRATCANTDGSFRCLCDTGYKGDGYGL-RTVCCVYSCVDID 527
C +D+DECL G C +C NT GSF CLC GY G C C
Sbjct: 429 CHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488
Query: 528 ECANDPTLCENGHCSNTPG--GYECDCD 553
C + L HC PG G C+ +
Sbjct: 489 TCLD---LLATFHCLCPPGLEGQLCEVE 513
Score = 118 bits (283), Expect = 7e-26
Identities = 127/459 (27%), Positives = 173/459 (37%), Gaps = 86/459 (18%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVC-G 172
+ E+ C + P C HG C G+ C C GY TC + + C G C
Sbjct: 689 EAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEMTACH--SGPCLN 740
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
G C+ + G + C C P + D C GG CVN G+F C C G
Sbjct: 741 GGSCNPSPGGYYCTCPPSHTGPQCQ---TSTDYCVSAPCF-NGGTCVNRPGTFSCLCAMG 796
Query: 233 MELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ P C+ S C N A C++ +C+C GY + ++
Sbjct: 797 FQ-GP---RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT--LMDLCAQ 850
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWH---LRADGRSCRD--IDECAGGARPC-GGGQCRN 345
R H C+ T S+HC C +GW SC+ + + + C GG C +
Sbjct: 851 KPCPRNSH-CLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVD 909
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
+ SY C C G S CQD V+P C G
Sbjct: 910 SGPSYFCHCPPGFQGS------LCQD---------------------HVNPCESRPCQNG 942
Query: 406 -SCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCR 463
+C ++CQC GY G C+ + D C+ + CH C PG F C C
Sbjct: 943 ATCMAQPSGYLCQCAPGY-----DGQNCSKELDACQ--SQPCHNHGTCTPKPGGFHCACP 995
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRAT--CANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ G CE DVDECL + CHP T C + +F C C G+ G
Sbjct: 996 PGF--VGLRCEGDVDECL--DQPCHPTGTAACHSLANAFYCQCLPGHTGQ---------- 1041
Query: 521 YSCVDIDECANDPTLCENGHCSNTPG---GYECDCDVGF 556
+ V+ID C + P G C T G G+ C C GF
Sbjct: 1042 WCEVEIDPCHSQPCF-HGGTCEATAGSPLGFICHCPKGF 1079
Score = 111 bits (268), Expect = 5e-24
Identities = 109/436 (25%), Positives = 164/436 (37%), Gaps = 70/436 (16%)
Query: 129 CGHGRCRNLLGGFTCDC-FPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
C HG C+ CD + G E +++ C+ C G C+ + C C
Sbjct: 667 CHHGHCQR--SSCVCDVGWTGPECEAELGGCISA-PC------AHGGTCYPQPSGYNCTC 717
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDE 247
GY S+ ++ C L GG C + G + C C P C+ +
Sbjct: 718 PTGYTGPTCSE---EMTACHSGPCL-NGGSCNPSPGGYYCTCPPS-HTGPQ---CQTSTD 769
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
+++ + G C N+ GT+ C+C G+ + R +C ++P
Sbjct: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA--TCQDSPQG 827
Query: 308 YHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGA 365
C C G+ G SC+ + D CA +PC C T S+ C C G
Sbjct: 828 PRCLCPTGY----TGGSCQTLMDLCA--QKPCPRNSHCLQTGPSFHCLCLQGWTG----- 876
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSV 424
P C + + S + S + LC G C ++ S+ C CP G+
Sbjct: 877 -PLCN-----------LPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-- 922
Query: 425 KPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTN 482
QG C D + CE + C A C+ P + C+C G+ DG C +++D C +
Sbjct: 923 ---QGSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPGY--DGQNCSKELDACQSQ 975
Query: 483 NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT-LCENGHC 541
CH TC G F C C G+ GLR C D+DEC + P C
Sbjct: 976 P--CHNHGTCTPKPGGFHCACPPGF----VGLR---CE---GDVDECLDQPCHPTGTAAC 1023
Query: 542 SNTPGGYECDCDVGFT 557
+ + C C G T
Sbjct: 1024 HSLANAFYCQCLPGHT 1039
Score = 111 bits (267), Expect = 6e-24
Identities = 118/414 (28%), Positives = 161/414 (38%), Gaps = 67/414 (16%)
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNT--------------AGSF 225
G TC C PG+ + C D C N LC+ GG C SF
Sbjct: 47 GQGTCQCAPGF----LGETCQFPDPC-QNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSF 101
Query: 226 RCECGHGMELAPDRLSCKDIDECSITSGICSN-GACENQM-GTYQCVCDEGYAQSTVKSH 283
C C G +R K D C CS G C Q G QC C G+ +
Sbjct: 102 LCTCLPGF--TGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR 157
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGG- 341
C+ T C C G+ +G +C RD++EC PC G
Sbjct: 158 DFCSANPCVNGG----VCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGT 209
Query: 342 QCRNTVGSYTCTCTDGLV-PSA---AGAKP--------TCQDIDECADLISTIIM---MS 386
C NT+GS+ C C G P AG P TCQ + E +
Sbjct: 210 SCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Query: 387 VDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECEL-GTC 443
+ + + D + C G+C + + ++ C CP+ ++ G C++D DECE G
Sbjct: 270 GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT-----GWDCSEDVDECETQGPP 324
Query: 444 DCHPAADCINLPGSFQCRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCL 502
C C N GSF C C GW G +CE+ +D+C+ C P +TC + GSF CL
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLDDCIAAT--CAPGSTCIDRVGSFSCL 380
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG--GYECDCDV 554
C G G L +C C +C+ +P L + C PG G C D+
Sbjct: 381 CPPGRTGLLCHLEDMCLSQPCHGDAQCSTNP-LTGSTLCLCQPGYSGPTCHQDL 433
Score = 73.3 bits (172), Expect = 2e-12
Identities = 115/474 (24%), Positives = 161/474 (33%), Gaps = 82/474 (17%)
Query: 131 HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN------TEGSFT 184
+ C F C C G+ N + + G+ CHN + S+
Sbjct: 856 NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF 915
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC-K 243
CHC PG++ +C D ++ G C+ + C+C G D +C K
Sbjct: 916 CHCPPGFQGS----LCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY----DGQNCSK 967
Query: 244 DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
++D C S C N G C + G + C C G+ + +C
Sbjct: 968 ELDACQ--SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTA-ACH 1024
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGS---YTCTCTDG 357
+ +++C C G H G+ C +ID C ++PC GG C T GS + C C G
Sbjct: 1025 SLANAFYCQCLPG-HT---GQWCEVEIDPCH--SQPCFHGGTCEATAGSPLGFICHCPKG 1078
Query: 358 LV-PSAAGAKPTCQDIDEC-----------ADLISTIIMMSVDELQKSVDPQIPELCGA- 404
P+ + P+C C +S + P P+ CG
Sbjct: 1079 FEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 1137
Query: 405 ------GSCHNTIG----SFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADCIN 453
GSC T G F C CP Q P + G CD + N
Sbjct: 1138 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1197
Query: 454 LPGSFQCRCR--DGWRGDGATCEDVDEC--LTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G C D W+G C C L +G CHP+ S CL D
Sbjct: 1198 WDGG-DCSLGVPDPWKG----CPSHSRCWLLFRDGQCHPQCD------SEECLFD----- 1241
Query: 510 DGYGLRTV-CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADG 562
GY T C + D+ +D NGHC EC D G R DG
Sbjct: 1242 -GYDCETPPACTPA---YDQYCHDHF--HNGHCEKGCNTAECGWDGGDCRPEDG 1289
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/230 (27%), Positives = 87/230 (37%), Gaps = 37/230 (16%)
Query: 331 CAGGARPCG-GGQCRN-TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
C PC GG C + ++G TC C G + CQ+ C + S ++
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
Query: 389 -ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
L S P P SF+C C G++ + Q +D C C
Sbjct: 88 LGLPSSPSPLTP-------------SFLCTCLPGFTGERCQAKL---EDPCPPSFCSKRG 131
Query: 448 AADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
I G QC C GW G+ C+ D C N C C T +C C G+
Sbjct: 132 RCH-IQASGRPQCSCMPGWTGE--QCQLRDFCSANP--CVNGGVCLATYPQIQCHCPPGF 186
Query: 508 KGDGYGLRTVCCVYSCV-DIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
+G ++C D++EC DP C G C NT G ++C C VG
Sbjct: 187 EG-----------HACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225
>D86566-1|BAA13116.1| 955|Homo sapiens notch related protein
protein.
Length = 955
Score = 155 bits (376), Expect = 4e-37
Identities = 144/463 (31%), Positives = 193/463 (41%), Gaps = 95/463 (20%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC PG C G C N LG F C C G E CE+ G C
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGP----------RCELRAGPCPPR 241
Query: 175 DCHN---------TEGSF-TCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGS 224
C N + +F C C PG+ D V+ D C + GG C + +
Sbjct: 242 GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---VNPDNCVSHQCQ-NGGTCQDGLDT 297
Query: 225 FRCECGHGMELAPDRLSCKDIDECSITSG--ICSN-GACENQMGTYQCVCDEGYAQSTVK 281
+ C C E +D+DEC T G C N G C+N G++ CVC G+ ++ +
Sbjct: 298 YTCLC---PETWTGWDCSEDVDECE-TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE 353
Query: 282 SHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GG 340
+ +C++ GS+ C C G G C D C ++PC G
Sbjct: 354 ENLDDCIAATCAPG---STCIDRVGSFSCLCPPG----RTGLLCHLEDMCL--SQPCHGD 404
Query: 341 GQCRNT--VGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDELQKSVDPQ 397
QC GS C C G + PTC QD+DEC +M+ Q
Sbjct: 405 AQCSTNPLTGSTLCLCQPGY------SGPTCHQDLDEC--------LMA---------QQ 441
Query: 398 IPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLP 455
P C GSC NT GSF C CP GY+ G C D +EC + CHP + C++L
Sbjct: 442 GPSPCEHGGSCLNTPGSFNCLCPPGYT-----GSRCEADHNECL--SQPCHPGSTCLDLL 494
Query: 456 GSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+F C C G +G CE + +EC + C A C + F+C+C G+ G
Sbjct: 495 ATFHCLCPPGL--EGQLCEVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSG----- 545
Query: 515 RTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
T C DIDEC + P C N G C + PG + C C GF
Sbjct: 546 -TRC----EEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF 581
Score = 145 bits (351), Expect = 4e-34
Identities = 135/465 (29%), Positives = 192/465 (41%), Gaps = 70/465 (15%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGV-CGDGD-CHNTEGSFTCHCRP 189
G C++ L +TC C P E + DV+ECE C +G C N+ GSF C C
Sbjct: 289 GTCQDGLDTYTCLC-P--ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVS 345
Query: 190 GYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC 248
G+ + ++D+C A C G C++ GSF C C G L C D C
Sbjct: 346 GWGGTSCEE---NLDDCIA--ATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC 396
Query: 249 SITSGICSNGACENQ--MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SCVNT 304
++ + C G+ C+C GY+ T C+H SC+NT
Sbjct: 397 -LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 305 PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTCTDGL---- 358
PGS++C C G+ G C D +EC ++PC G C + + ++ C C GL
Sbjct: 456 PGSFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPGLEGQL 509
Query: 359 --VPSAAGAKPTCQDIDECADLISTIIMM-----SVDELQKSVDPQIPELCG-AGSCHNT 410
V + A C + +C DL++ + S ++ +D C G C +
Sbjct: 510 CEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQ 569
Query: 411 IGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
G+F C+C G+ +GP C T+ DEC C A C++LPG+F C C G+ G
Sbjct: 570 PGAFHCKCLPGF-----EGPRCQTEVDECLSDPCPV--GASCLDLPGAFFCLCPSGFTGQ 622
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY------SC 523
CE V C N C P+ C + CLC G G C + SC
Sbjct: 623 --LCE-VPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 524 V-DI----DECANDPTLC------ENGHCSNTPGGYECDCDVGFT 557
V D+ EC + C G C P GY C C G+T
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 722
Score = 139 bits (336), Expect = 3e-32
Identities = 128/464 (27%), Positives = 181/464 (39%), Gaps = 75/464 (16%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++E NECA+ P L H C +LL GF C C PG+ S D++EC G G
Sbjct: 511 EVETNECASAPCL-NHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRSSPCANG-GQ 565
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME- 234
C + G+F C C PG++ + ++DEC +D G C++ G+F C C G
Sbjct: 566 CQDQPGAFHCKCLPGFEG---PRCQTEVDECL-SDPCPVGASCLDLPGAFFCLCPSGFTG 621
Query: 235 -------LAPDRLSCKDI--DECSITSGICSNGACENQMGTYQCVCDEGYAQSTV----- 280
AP+ K I D+ + +C +G+ C C G+ Q +
Sbjct: 622 QLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDV 681
Query: 281 --KSHXXXXXXXXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGA 335
C H +C P Y+CTC G+ G +C ++ C G
Sbjct: 682 GWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSG- 736
Query: 336 RPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV 394
PC GG C + G Y CTC PS G P C Q S
Sbjct: 737 -PCLNGGSCNPSPGGYYCTCP----PSHTG--PQC---------------------QTST 768
Query: 395 DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCIN 453
D + C G+C N G+F C C G+ QGP C C A C +
Sbjct: 769 DYCVSAPCFNGGTCVNRPGTFSCLCAMGF-----QGPRCEGKLRPSCADSPCRNRATCQD 823
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
P +C C G+ G +C+ + + L C + C T SF CLC G+ G
Sbjct: 824 SPQGPRCLCPTGY--TGGSCQTLMD-LCAQRPCPRNSHCLQTGPSFHCLCLQGWTGPLCN 880
Query: 514 LRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
L C + + + + +LC NG C ++ Y C C GF
Sbjct: 881 LPLSSCQKAA--LSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922
Score = 136 bits (330), Expect = 1e-31
Identities = 128/457 (28%), Positives = 179/457 (39%), Gaps = 72/457 (15%)
Query: 130 GHGRCRN--LLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVD---GVCGDG-DCHNTEGS 182
G +C L G C C PGY TC D++EC + C G C NT GS
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGS 458
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLS 241
F C C PGY S+ D +EC C G C++ +F C C G+E +L
Sbjct: 459 FNCLCPPGYTG---SRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE---GQLC 510
Query: 242 CKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+ +EC+ S C N A C + + +QC+C G++ + +
Sbjct: 511 EVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG---Q 565
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C + PG++HC C G+ +G C+ ++DEC P G C + G++ C C G
Sbjct: 566 CQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGAS-CLDLPGAFFCLCPSGFT 620
Query: 360 PSAAG----AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
A CQ C D + D P+ C G C +
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---- 676
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD---CINLPGSFQCRCRDGWRGDGAT 472
C C G++ GP C E ELG C P A C P + C C G+ G T
Sbjct: 677 CVCDVGWT-----GPEC----EAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGP--T 725
Query: 473 C-EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
C E++ C ++G C +C + G + C C + G T CV + C N
Sbjct: 726 CSEEMTAC--HSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA-----PCFN 778
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
G C N PG + C C +GF G C GK
Sbjct: 779 ------GGTCVNRPGTFSCLCAMGF----QGPRCEGK 805
Score = 135 bits (326), Expect = 5e-31
Identities = 131/448 (29%), Positives = 175/448 (39%), Gaps = 78/448 (17%)
Query: 126 PGLCG-HGRCRNLLGGFT-CDCFPGY--EKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
P C GRC G C C PG+ E+ C N C V+G G C T
Sbjct: 124 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-SANPC--VNG----GVCLATYP 176
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRL 240
CHC PG++ + D++EC + C +G C NT GSF+C C G E L
Sbjct: 177 QIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCEL 233
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH- 299
++G E + C+C G+ + + +CQ+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSH-----QCQNG 288
Query: 300 -SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARP-C-GGGQCRNTVGSYTCTCT 355
+C + +Y C C E W G C D+DEC P C GG C+N+ GS+ C C
Sbjct: 289 GTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSF 414
G G +++D+C I C GS C + +GSF
Sbjct: 345 SGW-----GGTSCEENLDDC----------------------IAATCAPGSTCIDRVGSF 377
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP--GSFQCRCRDGWRGDGAT 472
C CP G + G C +D C + CH A C P GS C C+ G+ G T
Sbjct: 378 SCLCPPGRT-----GLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLCQPGY--SGPT 428
Query: 473 C-EDVDECLTNNGG---CHPRATCANTDGSFRCLCDTGYKGDGYGL-RTVCCVYSCVDID 527
C +D+DECL G C +C NT GSF CLC GY G C C
Sbjct: 429 CHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488
Query: 528 ECANDPTLCENGHCSNTPG--GYECDCD 553
C + L HC PG G C+ +
Sbjct: 489 TCLD---LLATFHCLCPPGLEGQLCEVE 513
Score = 109 bits (263), Expect = 2e-23
Identities = 117/414 (28%), Positives = 161/414 (38%), Gaps = 67/414 (16%)
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNT--------------AGSF 225
G TC C PG+ + C D C N LC+ GG C SF
Sbjct: 47 GQGTCQCAPGF----LGETCQFPDPC-QNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSF 101
Query: 226 RCECGHGMELAPDRLSCKDIDECSITSGICSN-GACENQM-GTYQCVCDEGYAQSTVKSH 283
C C G +R + D C CS G C Q G QC C G+ +
Sbjct: 102 LCTCLPGF--TGERCQAQLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR 157
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGG- 341
C+ T C C G+ +G +C RD++EC PC G
Sbjct: 158 DFCSANPCVNGG----VCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGT 209
Query: 342 QCRNTVGSYTCTCTDGLV-PSA---AGAKP--------TCQDIDECADLISTIIM---MS 386
C NT+GS+ C C G P AG P TCQ + E +
Sbjct: 210 SCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Query: 387 VDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECEL-GTC 443
+ + + D + C G+C + + ++ C CP+ ++ G C++D DECE G
Sbjct: 270 GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT-----GWDCSEDVDECETQGPP 324
Query: 444 DCHPAADCINLPGSFQCRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCL 502
C C N GSF C C GW G +CE+ +D+C+ C P +TC + GSF CL
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLDDCIAAT--CAPGSTCIDRVGSFSCL 380
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG--GYECDCDV 554
C G G L +C C +C+ +P L + C PG G C D+
Sbjct: 381 CPPGRTGLLCHLEDMCLSQPCHGDAQCSTNP-LTGSTLCLCQPGYSGPTCHQDL 433
Score = 76.6 bits (180), Expect = 2e-13
Identities = 80/338 (23%), Positives = 124/338 (36%), Gaps = 54/338 (15%)
Query: 129 CGHGRCRNLLGGFTCDC-FPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
C HG C+ CD + G E +++ C+ C G C+ + C C
Sbjct: 667 CHHGHCQR--SSCVCDVGWTGPECEAELGGCISA-PC------AHGGTCYPQPSGYNCTC 717
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDE 247
GY S+ ++ C L GG C + G + C C P C+ +
Sbjct: 718 PTGYTGPTCSE---EMTACHSGPCL-NGGSCNPSPGGYYCTCPPS-HTGPQ---CQTSTD 769
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
+++ + G C N+ GT+ C+C G+ + R +C ++P
Sbjct: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA--TCQDSPQG 827
Query: 308 YHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGA 365
C C G+ G SC+ + D CA RPC C T S+ C C G
Sbjct: 828 PRCLCPTGY----TGGSCQTLMDLCA--QRPCPRNSHCLQTGPSFHCLCLQGWTG----- 876
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSV 424
P C + + S + S + LC G C ++ S+ C CP G+
Sbjct: 877 -PLCN-----------LPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-- 922
Query: 425 KPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCR 461
QG C D + CE + C A C+ P + C+
Sbjct: 923 ---QGSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQ 955
Score = 70.5 bits (165), Expect = 1e-11
Identities = 64/231 (27%), Positives = 86/231 (37%), Gaps = 39/231 (16%)
Query: 331 CAGGARPCG-GGQCRN-TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
C PC GG C + ++G TC C G + CQ+ C + S ++
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
Query: 389 -ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
L S P P SF+C C G++ G C E C
Sbjct: 88 LGLPSSPSPLTP-------------SFLCTCLPGFT-----GERCQAQLEDPCPPSFCSK 129
Query: 448 AADC-INLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
C I G QC C GW G+ C+ D C N C C T +C C G
Sbjct: 130 RGRCHIQASGRPQCSCMPGWTGE--QCQLRDFCSANP--CVNGGVCLATYPQIQCHCPPG 185
Query: 507 YKGDGYGLRTVCCVYSCV-DIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
++G ++C D++EC DP C G C NT G ++C C VG
Sbjct: 186 FEG-----------HACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225
Score = 52.8 bits (121), Expect = 3e-06
Identities = 61/246 (24%), Positives = 89/246 (36%), Gaps = 31/246 (12%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDC 176
E+ C + P L G G C GG+ C C P + + T D C V C G C
Sbjct: 729 EMTACHSGPCLNG-GSCNPSPGGYYCTCPPSHT-GPQCQTSTDY--C--VSAPCFNGGTC 782
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMEL 235
N G+F+C C G++ CAD+ CR C ++ RC C G
Sbjct: 783 VNRPGTFSCLCAMGFQGPRCEGKLRP--SCADSP--CRNRATCQDSPQGPRCLCPTGYTG 838
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVK-----SHXXXXXXX 290
SC+ + + N C ++ C+C +G+
Sbjct: 839 G----SCQTLMDLCAQRPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQG 894
Query: 291 XXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPC-GGGQCRNT 346
C + CV++ SY C C G+ G C+D ++ C +RPC G C
Sbjct: 895 IDVSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCE--SRPCQNGATCMAQ 948
Query: 347 VGSYTC 352
Y C
Sbjct: 949 PSGYLC 954
Score = 51.2 bits (117), Expect = 1e-05
Identities = 50/204 (24%), Positives = 72/204 (35%), Gaps = 23/204 (11%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-G 174
Q + C + P G G C N G F+C C G++ C D C +
Sbjct: 765 QTSTDYCVSAPCFNG-GTCVNRPGTFSCLCAMGFQ----GPRCEGKLRPSCADSPCRNRA 819
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C ++ C C GY + +D CA R C+ T SF C C G
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTL---MDLCAQRPCP-RNSHCLQTGPSFHCLCLQGWT 875
Query: 235 LAPDRLSCKDIDECSITSGI-----CSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXX 288
L + +++ GI C NG C + +Y C C G+ S + H
Sbjct: 876 GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH----- 930
Query: 289 XXXXXXXRCQH--SCVNTPGSYHC 310
CQ+ +C+ P Y C
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLC 954
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 155 bits (376), Expect = 4e-37
Identities = 144/463 (31%), Positives = 193/463 (41%), Gaps = 95/463 (20%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC PG C G C N LG F C C G E CE+ G C
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGP----------RCELRAGPCPPR 241
Query: 175 DCHN---------TEGSF-TCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGS 224
C N + +F C C PG+ D V+ D C + GG C + +
Sbjct: 242 GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---VNPDNCVSHQCQ-NGGTCQDGLDT 297
Query: 225 FRCECGHGMELAPDRLSCKDIDECSITSG--ICSN-GACENQMGTYQCVCDEGYAQSTVK 281
+ C C E +D+DEC T G C N G C+N G++ CVC G+ ++ +
Sbjct: 298 YTCLC---PETWTGWDCSEDVDECE-TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE 353
Query: 282 SHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GG 340
+ +C++ GS+ C C G G C D C ++PC G
Sbjct: 354 ENLDDCIAATCAPG---STCIDRVGSFSCLCPPG----RTGLLCHLEDMCL--SQPCHGD 404
Query: 341 GQCRNT--VGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDELQKSVDPQ 397
QC GS C C G + PTC QD+DEC +M+ Q
Sbjct: 405 AQCSTNPLTGSTLCLCQPGY------SGPTCHQDLDEC--------LMA---------QQ 441
Query: 398 IPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLP 455
P C GSC NT GSF C CP GY+ G C D +EC + CHP + C++L
Sbjct: 442 GPSPCEHGGSCLNTPGSFNCLCPPGYT-----GSRCEADHNECL--SQPCHPGSTCLDLL 494
Query: 456 GSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+F C C G +G CE + +EC + C A C + F+C+C G+ G
Sbjct: 495 ATFHCLCPPGL--EGQLCEVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSG----- 545
Query: 515 RTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
T C DIDEC + P C N G C + PG + C C GF
Sbjct: 546 -TRC----EEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF 581
Score = 145 bits (351), Expect = 4e-34
Identities = 135/465 (29%), Positives = 192/465 (41%), Gaps = 70/465 (15%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGV-CGDGD-CHNTEGSFTCHCRP 189
G C++ L +TC C P E + DV+ECE C +G C N+ GSF C C
Sbjct: 289 GTCQDGLDTYTCLC-P--ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVS 345
Query: 190 GYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC 248
G+ + ++D+C A C G C++ GSF C C G L C D C
Sbjct: 346 GWGGTSCEE---NLDDCIA--ATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC 396
Query: 249 SITSGICSNGACENQ--MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SCVNT 304
++ + C G+ C+C GY+ T C+H SC+NT
Sbjct: 397 -LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 305 PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTCTDGL---- 358
PGS++C C G+ G C D +EC ++PC G C + + ++ C C GL
Sbjct: 456 PGSFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPGLEGQL 509
Query: 359 --VPSAAGAKPTCQDIDECADLISTIIMM-----SVDELQKSVDPQIPELCG-AGSCHNT 410
V + A C + +C DL++ + S ++ +D C G C +
Sbjct: 510 CEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQ 569
Query: 411 IGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
G+F C+C G+ +GP C T+ DEC C A C++LPG+F C C G+ G
Sbjct: 570 PGAFHCKCLPGF-----EGPRCQTEVDECLSDPCPV--GASCLDLPGAFFCLCPSGFTGQ 622
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY------SC 523
CE V C N C P+ C + CLC G G C + SC
Sbjct: 623 --LCE-VPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 524 V-DI----DECANDPTLC------ENGHCSNTPGGYECDCDVGFT 557
V D+ EC + C G C P GY C C G+T
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 722
Score = 139 bits (336), Expect = 3e-32
Identities = 128/464 (27%), Positives = 181/464 (39%), Gaps = 75/464 (16%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++E NECA+ P L H C +LL GF C C PG+ S D++EC G G
Sbjct: 511 EVETNECASAPCL-NHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRSSPCANG-GQ 565
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME- 234
C + G+F C C PG++ + ++DEC +D G C++ G+F C C G
Sbjct: 566 CQDQPGAFHCKCLPGFEG---PRCQTEVDECL-SDPCPVGASCLDLPGAFFCLCPSGFTG 621
Query: 235 -------LAPDRLSCKDI--DECSITSGICSNGACENQMGTYQCVCDEGYAQSTV----- 280
AP+ K I D+ + +C +G+ C C G+ Q +
Sbjct: 622 QLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDV 681
Query: 281 --KSHXXXXXXXXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGA 335
C H +C P Y+CTC G+ G +C ++ C G
Sbjct: 682 GWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSG- 736
Query: 336 RPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV 394
PC GG C + G Y CTC PS G P C Q S
Sbjct: 737 -PCLNGGSCNPSPGGYYCTCP----PSHTG--PQC---------------------QTST 768
Query: 395 DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCIN 453
D + C G+C N G+F C C G+ QGP C C A C +
Sbjct: 769 DYCVSAPCFNGGTCVNRPGTFSCLCAMGF-----QGPRCEGKLRPSCADSPCRNRATCQD 823
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
P +C C G+ G +C+ + + L C + C T SF CLC G+ G
Sbjct: 824 SPQGPRCLCPTGY--TGGSCQTLMD-LCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCN 880
Query: 514 LRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
L C + + + + +LC NG C ++ Y C C GF
Sbjct: 881 LPLSSCQKAA--LSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922
Score = 136 bits (330), Expect = 1e-31
Identities = 128/457 (28%), Positives = 179/457 (39%), Gaps = 72/457 (15%)
Query: 130 GHGRCRN--LLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVD---GVCGDG-DCHNTEGS 182
G +C L G C C PGY TC D++EC + C G C NT GS
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGS 458
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLS 241
F C C PGY S+ D +EC C G C++ +F C C G+E +L
Sbjct: 459 FNCLCPPGYTG---SRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE---GQLC 510
Query: 242 CKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+ +EC+ S C N A C + + +QC+C G++ + +
Sbjct: 511 EVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG---Q 565
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C + PG++HC C G+ +G C+ ++DEC P G C + G++ C C G
Sbjct: 566 CQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGAS-CLDLPGAFFCLCPSGFT 620
Query: 360 PSAAG----AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
A CQ C D + D P+ C G C +
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---- 676
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD---CINLPGSFQCRCRDGWRGDGAT 472
C C G++ GP C E ELG C P A C P + C C G+ G T
Sbjct: 677 CVCDVGWT-----GPEC----EAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGP--T 725
Query: 473 C-EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
C E++ C ++G C +C + G + C C + G T CV + C N
Sbjct: 726 CSEEMTAC--HSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA-----PCFN 778
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
G C N PG + C C +GF G C GK
Sbjct: 779 ------GGTCVNRPGTFSCLCAMGF----QGPRCEGK 805
Score = 135 bits (326), Expect = 5e-31
Identities = 131/448 (29%), Positives = 175/448 (39%), Gaps = 78/448 (17%)
Query: 126 PGLCG-HGRCRNLLGGFT-CDCFPGY--EKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
P C GRC G C C PG+ E+ C N C V+G G C T
Sbjct: 124 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-SANPC--VNG----GVCLATYP 176
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRL 240
CHC PG++ + D++EC + C +G C NT GSF+C C G E L
Sbjct: 177 QIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCEL 233
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH- 299
++G E + C+C G+ + + +CQ+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSH-----QCQNG 288
Query: 300 -SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARP-C-GGGQCRNTVGSYTCTCT 355
+C + +Y C C E W G C D+DEC P C GG C+N+ GS+ C C
Sbjct: 289 GTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSF 414
G G +++D+C I C GS C + +GSF
Sbjct: 345 SGW-----GGTSCEENLDDC----------------------IAATCAPGSTCIDRVGSF 377
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP--GSFQCRCRDGWRGDGAT 472
C CP G + G C +D C + CH A C P GS C C+ G+ G T
Sbjct: 378 SCLCPPGRT-----GLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLCQPGY--SGPT 428
Query: 473 C-EDVDECLTNNGG---CHPRATCANTDGSFRCLCDTGYKGDGYGL-RTVCCVYSCVDID 527
C +D+DECL G C +C NT GSF CLC GY G C C
Sbjct: 429 CHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488
Query: 528 ECANDPTLCENGHCSNTPG--GYECDCD 553
C + L HC PG G C+ +
Sbjct: 489 TCLD---LLATFHCLCPPGLEGQLCEVE 513
Score = 118 bits (283), Expect = 7e-26
Identities = 127/459 (27%), Positives = 173/459 (37%), Gaps = 86/459 (18%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVC-G 172
+ E+ C + P C HG C G+ C C GY TC + + C G C
Sbjct: 689 EAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEMTACH--SGPCLN 740
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
G C+ + G + C C P + D C GG CVN G+F C C G
Sbjct: 741 GGSCNPSPGGYYCTCPPSHTGPQCQ---TSTDYCVSAPCF-NGGTCVNRPGTFSCLCAMG 796
Query: 233 MELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ P C+ S C N A C++ +C+C GY + ++
Sbjct: 797 FQ-GP---RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT--LMDLCAQ 850
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWH---LRADGRSCRD--IDECAGGARPC-GGGQCRN 345
R H C+ T S+HC C +GW SC+ + + + C GG C +
Sbjct: 851 KPCPRNSH-CLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVD 909
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
+ SY C C G S CQD V+P C G
Sbjct: 910 SGPSYFCHCPPGFQGS------LCQD---------------------HVNPCESRPCQNG 942
Query: 406 -SCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCR 463
+C ++CQC GY G C+ + D C+ + CH C PG F C C
Sbjct: 943 ATCMAQPSGYLCQCAPGY-----DGQNCSKELDACQ--SQPCHNHGTCTPKPGGFHCACP 995
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRAT--CANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ G CE DVDECL + CHP T C + +F C C G+ G
Sbjct: 996 PGF--VGLRCEGDVDECL--DQPCHPTGTAACHSLANAFYCQCLPGHTGQ---------- 1041
Query: 521 YSCVDIDECANDPTLCENGHCSNTPG---GYECDCDVGF 556
+ V+ID C + P G C T G G+ C C GF
Sbjct: 1042 WCEVEIDPCHSQPCF-HGGTCEATAGSPLGFICHCPKGF 1079
Score = 111 bits (268), Expect = 5e-24
Identities = 109/436 (25%), Positives = 164/436 (37%), Gaps = 70/436 (16%)
Query: 129 CGHGRCRNLLGGFTCDC-FPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
C HG C+ CD + G E +++ C+ C G C+ + C C
Sbjct: 667 CHHGHCQR--SSCVCDVGWTGPECEAELGGCISA-PC------AHGGTCYPQPSGYNCTC 717
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDE 247
GY S+ ++ C L GG C + G + C C P C+ +
Sbjct: 718 PTGYTGPTCSE---EMTACHSGPCL-NGGSCNPSPGGYYCTCPPS-HTGPQ---CQTSTD 769
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
+++ + G C N+ GT+ C+C G+ + R +C ++P
Sbjct: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA--TCQDSPQG 827
Query: 308 YHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGA 365
C C G+ G SC+ + D CA +PC C T S+ C C G
Sbjct: 828 PRCLCPTGY----TGGSCQTLMDLCA--QKPCPRNSHCLQTGPSFHCLCLQGWTG----- 876
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSV 424
P C + + S + S + LC G C ++ S+ C CP G+
Sbjct: 877 -PLCN-----------LPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-- 922
Query: 425 KPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTN 482
QG C D + CE + C A C+ P + C+C G+ DG C +++D C +
Sbjct: 923 ---QGSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPGY--DGQNCSKELDACQSQ 975
Query: 483 NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT-LCENGHC 541
CH TC G F C C G+ GLR C D+DEC + P C
Sbjct: 976 P--CHNHGTCTPKPGGFHCACPPGF----VGLR---CE---GDVDECLDQPCHPTGTAAC 1023
Query: 542 SNTPGGYECDCDVGFT 557
+ + C C G T
Sbjct: 1024 HSLANAFYCQCLPGHT 1039
Score = 111 bits (267), Expect = 6e-24
Identities = 118/414 (28%), Positives = 161/414 (38%), Gaps = 67/414 (16%)
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNT--------------AGSF 225
G TC C PG+ + C D C N LC+ GG C SF
Sbjct: 47 GQGTCQCAPGF----LGETCQFPDPC-QNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSF 101
Query: 226 RCECGHGMELAPDRLSCKDIDECSITSGICSN-GACENQM-GTYQCVCDEGYAQSTVKSH 283
C C G +R K D C CS G C Q G QC C G+ +
Sbjct: 102 LCTCLPGF--TGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR 157
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGG- 341
C+ T C C G+ +G +C RD++EC PC G
Sbjct: 158 DFCSANPCVNGG----VCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGT 209
Query: 342 QCRNTVGSYTCTCTDGLV-PSA---AGAKP--------TCQDIDECADLISTIIM---MS 386
C NT+GS+ C C G P AG P TCQ + E +
Sbjct: 210 SCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Query: 387 VDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECEL-GTC 443
+ + + D + C G+C + + ++ C CP+ ++ G C++D DECE G
Sbjct: 270 GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT-----GWDCSEDVDECETQGPP 324
Query: 444 DCHPAADCINLPGSFQCRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCL 502
C C N GSF C C GW G +CE+ +D+C+ C P +TC + GSF CL
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLDDCIAAT--CAPGSTCIDRVGSFSCL 380
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG--GYECDCDV 554
C G G L +C C +C+ +P L + C PG G C D+
Sbjct: 381 CPPGRTGLLCHLEDMCLSQPCHGDAQCSTNP-LTGSTLCLCQPGYSGPTCHQDL 433
Score = 73.3 bits (172), Expect = 2e-12
Identities = 115/474 (24%), Positives = 161/474 (33%), Gaps = 82/474 (17%)
Query: 131 HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN------TEGSFT 184
+ C F C C G+ N + + G+ CHN + S+
Sbjct: 856 NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF 915
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC-K 243
CHC PG++ +C D ++ G C+ + C+C G D +C K
Sbjct: 916 CHCPPGFQGS----LCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY----DGQNCSK 967
Query: 244 DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
++D C S C N G C + G + C C G+ + +C
Sbjct: 968 ELDACQ--SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTA-ACH 1024
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGS---YTCTCTDG 357
+ +++C C G H G+ C +ID C ++PC GG C T GS + C C G
Sbjct: 1025 SLANAFYCQCLPG-HT---GQWCEVEIDPCH--SQPCFHGGTCEATAGSPLGFICHCPKG 1078
Query: 358 LV-PSAAGAKPTCQDIDEC-----------ADLISTIIMMSVDELQKSVDPQIPELCGA- 404
P+ + P+C C +S + P P+ CG
Sbjct: 1079 FEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 1137
Query: 405 ------GSCHNTIG----SFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADCIN 453
GSC T G F C CP Q P + G CD + N
Sbjct: 1138 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1197
Query: 454 LPGSFQCRCR--DGWRGDGATCEDVDEC--LTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G C D W+G C C L +G CHP+ S CL D
Sbjct: 1198 WDGG-DCSLGVPDPWKG----CPSHSRCWLLFRDGQCHPQCD------SEECLFD----- 1241
Query: 510 DGYGLRTV-CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADG 562
GY T C + D+ +D NGHC EC D G R DG
Sbjct: 1242 -GYDCETPPACTPA---YDQYCHDHF--HNGHCEKGCNTAECGWDGGDCRPEDG 1289
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/230 (27%), Positives = 87/230 (37%), Gaps = 37/230 (16%)
Query: 331 CAGGARPCG-GGQCRN-TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
C PC GG C + ++G TC C G + CQ+ C + S ++
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
Query: 389 -ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
L S P P SF+C C G++ + Q +D C C
Sbjct: 88 LGLPSSPSPLTP-------------SFLCTCLPGFTGERCQAKL---EDPCPPSFCSKRG 131
Query: 448 AADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
I G QC C GW G+ C+ D C N C C T +C C G+
Sbjct: 132 RCH-IQASGRPQCSCMPGWTGE--QCQLRDFCSANP--CVNGGVCLATYPQIQCHCPPGF 186
Query: 508 KGDGYGLRTVCCVYSCV-DIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
+G ++C D++EC DP C G C NT G ++C C VG
Sbjct: 187 EG-----------HACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 155 bits (376), Expect = 4e-37
Identities = 144/463 (31%), Positives = 193/463 (41%), Gaps = 95/463 (20%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC PG C G C N LG F C C G E CE+ G C
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGP----------RCELRAGPCPPR 241
Query: 175 DCHN---------TEGSF-TCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGS 224
C N + +F C C PG+ D V+ D C + GG C + +
Sbjct: 242 GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---VNPDNCVSHQCQ-NGGTCQDGLDT 297
Query: 225 FRCECGHGMELAPDRLSCKDIDECSITSG--ICSN-GACENQMGTYQCVCDEGYAQSTVK 281
+ C C E +D+DEC T G C N G C+N G++ CVC G+ ++ +
Sbjct: 298 YTCLC---PETWTGWDCSEDVDECE-TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE 353
Query: 282 SHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GG 340
+ +C++ GS+ C C G G C D C ++PC G
Sbjct: 354 ENLDDCIAATCAPG---STCIDRVGSFSCLCPPG----RTGLLCHLEDMCL--SQPCHGD 404
Query: 341 GQCRNT--VGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDELQKSVDPQ 397
QC GS C C G + PTC QD+DEC +M+ Q
Sbjct: 405 AQCSTNPLTGSTLCLCQPGY------SGPTCHQDLDEC--------LMA---------QQ 441
Query: 398 IPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLP 455
P C GSC NT GSF C CP GY+ G C D +EC + CHP + C++L
Sbjct: 442 GPSPCEHGGSCLNTPGSFNCLCPPGYT-----GSRCEADHNECL--SQPCHPGSTCLDLL 494
Query: 456 GSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+F C C G +G CE + +EC + C A C + F+C+C G+ G
Sbjct: 495 ATFHCLCPPGL--EGQLCEVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSG----- 545
Query: 515 RTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
T C DIDEC + P C N G C + PG + C C GF
Sbjct: 546 -TRC----EEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF 581
Score = 145 bits (351), Expect = 4e-34
Identities = 135/465 (29%), Positives = 192/465 (41%), Gaps = 70/465 (15%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGV-CGDGD-CHNTEGSFTCHCRP 189
G C++ L +TC C P E + DV+ECE C +G C N+ GSF C C
Sbjct: 289 GTCQDGLDTYTCLC-P--ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVS 345
Query: 190 GYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC 248
G+ + ++D+C A C G C++ GSF C C G L C D C
Sbjct: 346 GWGGTSCEE---NLDDCIA--ATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC 396
Query: 249 SITSGICSNGACENQ--MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SCVNT 304
++ + C G+ C+C GY+ T C+H SC+NT
Sbjct: 397 -LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 305 PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTCTDGL---- 358
PGS++C C G+ G C D +EC ++PC G C + + ++ C C GL
Sbjct: 456 PGSFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPGLEGQL 509
Query: 359 --VPSAAGAKPTCQDIDECADLISTIIMM-----SVDELQKSVDPQIPELCG-AGSCHNT 410
V + A C + +C DL++ + S ++ +D C G C +
Sbjct: 510 CEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQ 569
Query: 411 IGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
G+F C+C G+ +GP C T+ DEC C A C++LPG+F C C G+ G
Sbjct: 570 PGAFHCKCLPGF-----EGPRCQTEVDECLSDPCPV--GASCLDLPGAFFCLCPSGFTGQ 622
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY------SC 523
CE V C N C P+ C + CLC G G C + SC
Sbjct: 623 --LCE-VPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 524 V-DI----DECANDPTLC------ENGHCSNTPGGYECDCDVGFT 557
V D+ EC + C G C P GY C C G+T
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 722
Score = 139 bits (336), Expect = 3e-32
Identities = 128/464 (27%), Positives = 181/464 (39%), Gaps = 75/464 (16%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++E NECA+ P L H C +LL GF C C PG+ S D++EC G G
Sbjct: 511 EVETNECASAPCL-NHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRSSPCANG-GQ 565
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME- 234
C + G+F C C PG++ + ++DEC +D G C++ G+F C C G
Sbjct: 566 CQDQPGAFHCKCLPGFEG---PRCQTEVDECL-SDPCPVGASCLDLPGAFFCLCPSGFTG 621
Query: 235 -------LAPDRLSCKDI--DECSITSGICSNGACENQMGTYQCVCDEGYAQSTV----- 280
AP+ K I D+ + +C +G+ C C G+ Q +
Sbjct: 622 QLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDV 681
Query: 281 --KSHXXXXXXXXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGA 335
C H +C P Y+CTC G+ G +C ++ C G
Sbjct: 682 GWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSG- 736
Query: 336 RPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV 394
PC GG C + G Y CTC PS G P C Q S
Sbjct: 737 -PCLNGGSCNPSPGGYYCTCP----PSHTG--PQC---------------------QTST 768
Query: 395 DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCIN 453
D + C G+C N G+F C C G+ QGP C C A C +
Sbjct: 769 DYCVSAPCFNGGTCVNRPGTFSCLCAMGF-----QGPRCEGKLRPSCADSPCRNRATCQD 823
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
P +C C G+ G +C+ + + L C + C T SF CLC G+ G
Sbjct: 824 SPQGPRCLCPTGY--TGGSCQTLMD-LCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCN 880
Query: 514 LRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
L C + + + + +LC NG C ++ Y C C GF
Sbjct: 881 LPLSSCQKAA--LSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922
Score = 136 bits (330), Expect = 1e-31
Identities = 128/457 (28%), Positives = 179/457 (39%), Gaps = 72/457 (15%)
Query: 130 GHGRCRN--LLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVD---GVCGDG-DCHNTEGS 182
G +C L G C C PGY TC D++EC + C G C NT GS
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGS 458
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLS 241
F C C PGY S+ D +EC C G C++ +F C C G+E +L
Sbjct: 459 FNCLCPPGYTG---SRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE---GQLC 510
Query: 242 CKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+ +EC+ S C N A C + + +QC+C G++ + +
Sbjct: 511 EVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG---Q 565
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C + PG++HC C G+ +G C+ ++DEC P G C + G++ C C G
Sbjct: 566 CQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGAS-CLDLPGAFFCLCPSGFT 620
Query: 360 PSAAG----AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
A CQ C D + D P+ C G C +
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---- 676
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD---CINLPGSFQCRCRDGWRGDGAT 472
C C G++ GP C E ELG C P A C P + C C G+ G T
Sbjct: 677 CVCDVGWT-----GPEC----EAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGP--T 725
Query: 473 C-EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
C E++ C ++G C +C + G + C C + G T CV + C N
Sbjct: 726 CSEEMTAC--HSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA-----PCFN 778
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
G C N PG + C C +GF G C GK
Sbjct: 779 ------GGTCVNRPGTFSCLCAMGF----QGPRCEGK 805
Score = 135 bits (326), Expect = 5e-31
Identities = 131/448 (29%), Positives = 175/448 (39%), Gaps = 78/448 (17%)
Query: 126 PGLCG-HGRCRNLLGGFT-CDCFPGY--EKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
P C GRC G C C PG+ E+ C N C V+G G C T
Sbjct: 124 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-SANPC--VNG----GVCLATYP 176
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRL 240
CHC PG++ + D++EC + C +G C NT GSF+C C G E L
Sbjct: 177 QIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCEL 233
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH- 299
++G E + C+C G+ + + +CQ+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSH-----QCQNG 288
Query: 300 -SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARP-C-GGGQCRNTVGSYTCTCT 355
+C + +Y C C E W G C D+DEC P C GG C+N+ GS+ C C
Sbjct: 289 GTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSF 414
G G +++D+C I C GS C + +GSF
Sbjct: 345 SGW-----GGTSCEENLDDC----------------------IAATCAPGSTCIDRVGSF 377
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP--GSFQCRCRDGWRGDGAT 472
C CP G + G C +D C + CH A C P GS C C+ G+ G T
Sbjct: 378 SCLCPPGRT-----GLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLCQPGY--SGPT 428
Query: 473 C-EDVDECLTNNGG---CHPRATCANTDGSFRCLCDTGYKGDGYGL-RTVCCVYSCVDID 527
C +D+DECL G C +C NT GSF CLC GY G C C
Sbjct: 429 CHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488
Query: 528 ECANDPTLCENGHCSNTPG--GYECDCD 553
C + L HC PG G C+ +
Sbjct: 489 TCLD---LLATFHCLCPPGLEGQLCEVE 513
Score = 118 bits (283), Expect = 7e-26
Identities = 127/459 (27%), Positives = 173/459 (37%), Gaps = 86/459 (18%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVC-G 172
+ E+ C + P C HG C G+ C C GY TC + + C G C
Sbjct: 689 EAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEMTACH--SGPCLN 740
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
G C+ + G + C C P + D C GG CVN G+F C C G
Sbjct: 741 GGSCNPSPGGYYCTCPPSHTGPQCQ---TSTDYCVSAPCF-NGGTCVNRPGTFSCLCAMG 796
Query: 233 MELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ P C+ S C N A C++ +C+C GY + ++
Sbjct: 797 FQ-GP---RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT--LMDLCAQ 850
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWH---LRADGRSCRD--IDECAGGARPC-GGGQCRN 345
R H C+ T S+HC C +GW SC+ + + + C GG C +
Sbjct: 851 KPCPRNSH-CLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVD 909
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
+ SY C C G S CQD V+P C G
Sbjct: 910 SGPSYFCHCPPGFQGS------LCQD---------------------HVNPCESRPCQNG 942
Query: 406 -SCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCR 463
+C ++CQC GY G C+ + D C+ + CH C PG F C C
Sbjct: 943 ATCMAQPSGYLCQCAPGY-----DGQNCSKELDACQ--SQPCHNHGTCTPKPGGFHCACP 995
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRAT--CANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ G CE DVDECL + CHP T C + +F C C G+ G
Sbjct: 996 PGF--VGLRCEGDVDECL--DQPCHPTGTAACHSLANAFYCQCLPGHTGQ---------- 1041
Query: 521 YSCVDIDECANDPTLCENGHCSNTPG---GYECDCDVGF 556
+ V+ID C + P G C T G G+ C C GF
Sbjct: 1042 WCEVEIDPCHSQPCF-HGGTCEATAGSPLGFICHCPKGF 1079
Score = 111 bits (268), Expect = 5e-24
Identities = 109/436 (25%), Positives = 164/436 (37%), Gaps = 70/436 (16%)
Query: 129 CGHGRCRNLLGGFTCDC-FPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
C HG C+ CD + G E +++ C+ C G C+ + C C
Sbjct: 667 CHHGHCQR--SSCVCDVGWTGPECEAELGGCISA-PC------AHGGTCYPQPSGYNCTC 717
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDE 247
GY S+ ++ C L GG C + G + C C P C+ +
Sbjct: 718 PTGYTGPTCSE---EMTACHSGPCL-NGGSCNPSPGGYYCTCPPS-HTGPQ---CQTSTD 769
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
+++ + G C N+ GT+ C+C G+ + R +C ++P
Sbjct: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA--TCQDSPQG 827
Query: 308 YHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGA 365
C C G+ G SC+ + D CA +PC C T S+ C C G
Sbjct: 828 PRCLCPTGY----TGGSCQTLMDLCA--QKPCPRNSHCLQTGPSFHCLCLQGWTG----- 876
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSV 424
P C + + S + S + LC G C ++ S+ C CP G+
Sbjct: 877 -PLCN-----------LPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-- 922
Query: 425 KPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTN 482
QG C D + CE + C A C+ P + C+C G+ DG C +++D C +
Sbjct: 923 ---QGSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPGY--DGQNCSKELDACQSQ 975
Query: 483 NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT-LCENGHC 541
CH TC G F C C G+ GLR C D+DEC + P C
Sbjct: 976 P--CHNHGTCTPKPGGFHCACPPGF----VGLR---CE---GDVDECLDQPCHPTGTAAC 1023
Query: 542 SNTPGGYECDCDVGFT 557
+ + C C G T
Sbjct: 1024 HSLANAFYCQCLPGHT 1039
Score = 111 bits (267), Expect = 6e-24
Identities = 118/414 (28%), Positives = 161/414 (38%), Gaps = 67/414 (16%)
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNT--------------AGSF 225
G TC C PG+ + C D C N LC+ GG C SF
Sbjct: 47 GQGTCQCAPGF----LGETCQFPDPC-QNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSF 101
Query: 226 RCECGHGMELAPDRLSCKDIDECSITSGICSN-GACENQM-GTYQCVCDEGYAQSTVKSH 283
C C G +R K D C CS G C Q G QC C G+ +
Sbjct: 102 LCTCLPGF--TGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR 157
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGG- 341
C+ T C C G+ +G +C RD++EC PC G
Sbjct: 158 DFCSANPCVNGG----VCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGT 209
Query: 342 QCRNTVGSYTCTCTDGLV-PSA---AGAKP--------TCQDIDECADLISTIIM---MS 386
C NT+GS+ C C G P AG P TCQ + E +
Sbjct: 210 SCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Query: 387 VDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECEL-GTC 443
+ + + D + C G+C + + ++ C CP+ ++ G C++D DECE G
Sbjct: 270 GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT-----GWDCSEDVDECETQGPP 324
Query: 444 DCHPAADCINLPGSFQCRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCL 502
C C N GSF C C GW G +CE+ +D+C+ C P +TC + GSF CL
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLDDCIAAT--CAPGSTCIDRVGSFSCL 380
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG--GYECDCDV 554
C G G L +C C +C+ +P L + C PG G C D+
Sbjct: 381 CPPGRTGLLCHLEDMCLSQPCHGDAQCSTNP-LTGSTLCLCQPGYSGPTCHQDL 433
Score = 73.3 bits (172), Expect = 2e-12
Identities = 115/474 (24%), Positives = 161/474 (33%), Gaps = 82/474 (17%)
Query: 131 HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN------TEGSFT 184
+ C F C C G+ N + + G+ CHN + S+
Sbjct: 856 NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF 915
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC-K 243
CHC PG++ +C D ++ G C+ + C+C G D +C K
Sbjct: 916 CHCPPGFQGS----LCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY----DGQNCSK 967
Query: 244 DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
++D C S C N G C + G + C C G+ + +C
Sbjct: 968 ELDACQ--SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTA-ACH 1024
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGS---YTCTCTDG 357
+ +++C C G H G+ C +ID C ++PC GG C T GS + C C G
Sbjct: 1025 SLANAFYCQCLPG-HT---GQWCEVEIDPCH--SQPCFHGGTCEATAGSPLGFICHCPKG 1078
Query: 358 LV-PSAAGAKPTCQDIDEC-----------ADLISTIIMMSVDELQKSVDPQIPELCGA- 404
P+ + P+C C +S + P P+ CG
Sbjct: 1079 FEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 1137
Query: 405 ------GSCHNTIG----SFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADCIN 453
GSC T G F C CP Q P + G CD + N
Sbjct: 1138 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1197
Query: 454 LPGSFQCRCR--DGWRGDGATCEDVDEC--LTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G C D W+G C C L +G CHP+ S CL D
Sbjct: 1198 WDGG-DCSLGVPDPWKG----CPSHSRCWLLFRDGQCHPQCD------SEECLFD----- 1241
Query: 510 DGYGLRTV-CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADG 562
GY T C + D+ +D NGHC EC D G R DG
Sbjct: 1242 -GYDCETPPACTPA---YDQYCHDHF--HNGHCEKGCNTAECGWDGGDCRPEDG 1289
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/230 (27%), Positives = 87/230 (37%), Gaps = 37/230 (16%)
Query: 331 CAGGARPCG-GGQCRN-TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
C PC GG C + ++G TC C G + CQ+ C + S ++
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
Query: 389 -ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
L S P P SF+C C G++ + Q +D C C
Sbjct: 88 LGLPSSPSPLTP-------------SFLCTCLPGFTGERCQAKL---EDPCPPSFCSKRG 131
Query: 448 AADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
I G QC C GW G+ C+ D C N C C T +C C G+
Sbjct: 132 RCH-IQASGRPQCSCMPGWTGE--QCQLRDFCSANP--CVNGGVCLATYPQIQCHCPPGF 186
Query: 508 KGDGYGLRTVCCVYSCV-DIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
+G ++C D++EC DP C G C NT G ++C C VG
Sbjct: 187 EG-----------HACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 155 bits (376), Expect = 4e-37
Identities = 144/463 (31%), Positives = 193/463 (41%), Gaps = 95/463 (20%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC PG C G C N LG F C C G E CE+ G C
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGP----------RCELRAGPCPPR 241
Query: 175 DCHN---------TEGSF-TCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGS 224
C N + +F C C PG+ D V+ D C + GG C + +
Sbjct: 242 GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---VNPDNCVSHQCQ-NGGTCQDGLDT 297
Query: 225 FRCECGHGMELAPDRLSCKDIDECSITSG--ICSN-GACENQMGTYQCVCDEGYAQSTVK 281
+ C C E +D+DEC T G C N G C+N G++ CVC G+ ++ +
Sbjct: 298 YTCLC---PETWTGWDCSEDVDECE-TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE 353
Query: 282 SHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GG 340
+ +C++ GS+ C C G G C D C ++PC G
Sbjct: 354 ENLDDCIAATCAPG---STCIDRVGSFSCLCPPG----RTGLLCHLEDMCL--SQPCHGD 404
Query: 341 GQCRNT--VGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDELQKSVDPQ 397
QC GS C C G + PTC QD+DEC +M+ Q
Sbjct: 405 AQCSTNPLTGSTLCLCQPGY------SGPTCHQDLDEC--------LMA---------QQ 441
Query: 398 IPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLP 455
P C GSC NT GSF C CP GY+ G C D +EC + CHP + C++L
Sbjct: 442 GPSPCEHGGSCLNTPGSFNCLCPPGYT-----GSRCEADHNECL--SQPCHPGSTCLDLL 494
Query: 456 GSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+F C C G +G CE + +EC + C A C + F+C+C G+ G
Sbjct: 495 ATFHCLCPPGL--EGQLCEVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSG----- 545
Query: 515 RTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
T C DIDEC + P C N G C + PG + C C GF
Sbjct: 546 -TRC----EEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF 581
Score = 135 bits (326), Expect = 5e-31
Identities = 131/448 (29%), Positives = 175/448 (39%), Gaps = 78/448 (17%)
Query: 126 PGLCG-HGRCRNLLGGFT-CDCFPGY--EKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
P C GRC G C C PG+ E+ C N C V+G G C T
Sbjct: 124 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-SANPC--VNG----GVCLATYP 176
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRL 240
CHC PG++ + D++EC + C +G C NT GSF+C C G E L
Sbjct: 177 QIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCEL 233
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH- 299
++G E + C+C G+ + + +CQ+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSH-----QCQNG 288
Query: 300 -SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARP-C-GGGQCRNTVGSYTCTCT 355
+C + +Y C C E W G C D+DEC P C GG C+N+ GS+ C C
Sbjct: 289 GTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSF 414
G G +++D+C I C GS C + +GSF
Sbjct: 345 SGW-----GGTSCEENLDDC----------------------IAATCAPGSTCIDRVGSF 377
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP--GSFQCRCRDGWRGDGAT 472
C CP G + G C +D C + CH A C P GS C C+ G+ G T
Sbjct: 378 SCLCPPGRT-----GLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLCQPGY--SGPT 428
Query: 473 C-EDVDECLTNNGG---CHPRATCANTDGSFRCLCDTGYKGDGYGL-RTVCCVYSCVDID 527
C +D+DECL G C +C NT GSF CLC GY G C C
Sbjct: 429 CHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488
Query: 528 ECANDPTLCENGHCSNTPG--GYECDCD 553
C + L HC PG G C+ +
Sbjct: 489 TCLD---LLATFHCLCPPGLEGQLCEVE 513
Score = 133 bits (321), Expect = 2e-30
Identities = 127/447 (28%), Positives = 175/447 (39%), Gaps = 87/447 (19%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++E NECA+ P L H C +LL GF C C PG+ S D++EC G G
Sbjct: 511 EVETNECASAPCL-NHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRSSPCANG-GQ 565
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C + G+F C C PG++ + ++DEC +D G C++ G+F C C G
Sbjct: 566 CQDQPGAFHCKCLPGFEGP---RCQTEVDECL-SDPCPVGASCLDLPGAFFCLCPSGFT- 620
Query: 236 APDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+L C ++ C+ +C C++Q C+C +G
Sbjct: 621 --GQL-C-EVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHG---- 670
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTC 352
CQ S C C GW G C ++ C PC GG C Y C
Sbjct: 671 -HCQRSS--------CVCDVGW----TGPECEAELGGCISA--PCAHGGTCYPQPSGYNC 715
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
TC G PTC + + + P L G GSC+ + G
Sbjct: 716 TCPTGYTG------PTCSE-------------------EMTACHSGPCLNG-GSCNPSPG 749
Query: 413 SFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
+ C CP ++ GP C T D C + C C+N PG+F C C G++G
Sbjct: 750 GYYCTCPPSHT-----GPQCQTSTDYCV--SAPCFNGGTCVNRPGTFSCLCAMGFQGP-- 800
Query: 472 TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI-DECA 530
CE + C RATC ++ RCLC T Y G SC + D CA
Sbjct: 801 RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYTGG-----------SCQTLMDLCA 849
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFT 557
P N HC T + C C G+T
Sbjct: 850 QKP-CPRNSHCLQTGPSFHCLCLQGWT 875
Score = 126 bits (305), Expect = 2e-28
Identities = 122/442 (27%), Positives = 177/442 (40%), Gaps = 57/442 (12%)
Query: 126 PGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSF 183
P C HG C N G F C C PGY + + D NEC + C G C + +F
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGY---TGSRCEADHNEC--LSQPCHPGSTCLDLLATF 497
Query: 184 TCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC 242
C C PG + ++C V+ +ECA L C + F+C C G + R
Sbjct: 498 HCLCPPGLEG----QLCEVETNECASAPCLNHAD-CHDLLNGFQCICLPGF--SGTRCE- 549
Query: 243 KDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
+DIDEC S C+NG C++Q G + C C G+ ++ SC
Sbjct: 550 EDIDECR--SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGA---SC 604
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVP 360
++ PG++ C C G+ G+ C ++ CA C Q C++ C C DG P
Sbjct: 605 LDLPGAFFCLCPSGF----TGQLC-EVPLCAPNL--CQPKQICKDQKDKANCLCPDGS-P 656
Query: 361 SAAGAKPTCQDIDECADLISTI--IMMSVDELQKSVDPQIPELCG-AGSCHNTIGSFVCQ 417
A + C S + + + E + + I C G+C+ + C
Sbjct: 657 GCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCT 716
Query: 418 CPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-D 475
CP GY+ GP C+++ C G C C PG + C C G C+
Sbjct: 717 CPTGYT-----GPTCSEEMTACHSGPC--LNGGSCNPSPGGYYCTCPPSHTGP--QCQTS 767
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
D C++ C TC N G+F CLC G++G + SC D C N T
Sbjct: 768 TDYCVS--APCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK---LRPSCAD-SPCRNRAT- 820
Query: 536 CENGHCSNTPGGYECDCDVGFT 557
C ++P G C C +T
Sbjct: 821 -----CQDSPQGPRCLCPTVYT 837
Score = 114 bits (274), Expect = 9e-25
Identities = 126/459 (27%), Positives = 172/459 (37%), Gaps = 86/459 (18%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVC-G 172
+ E+ C + P C HG C G+ C C GY TC + + C G C
Sbjct: 689 EAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEMTACH--SGPCLN 740
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
G C+ + G + C C P + D C GG CVN G+F C C G
Sbjct: 741 GGSCNPSPGGYYCTCPPSHTGPQCQ---TSTDYCVSAPCF-NGGTCVNRPGTFSCLCAMG 796
Query: 233 MELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ P C+ S C N A C++ +C+C Y + ++
Sbjct: 797 FQ-GP---RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYTGGSCQT--LMDLCAQ 850
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWH---LRADGRSCRD--IDECAGGARPC-GGGQCRN 345
R H C+ T S+HC C +GW SC+ + + + C GG C +
Sbjct: 851 KPCPRNSH-CLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVD 909
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
+ SY C C G S CQD V+P C G
Sbjct: 910 SGPSYFCHCPPGFQGS------LCQD---------------------HVNPCESRPCQNG 942
Query: 406 -SCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCR 463
+C ++CQC GY G C+ + D C+ + CH C PG F C C
Sbjct: 943 ATCMAQPSGYLCQCAPGY-----DGQNCSKELDACQ--SQPCHNHGTCTPKPGGFHCACP 995
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRAT--CANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ G CE DVDECL + CHP T C + +F C C G+ G
Sbjct: 996 PGF--VGLRCEGDVDECL--DQPCHPTGTAACHSLANAFYCQCLPGHTGQ---------- 1041
Query: 521 YSCVDIDECANDPTLCENGHCSNTPG---GYECDCDVGF 556
+ V+ID C + P G C T G G+ C C GF
Sbjct: 1042 WCEVEIDPCHSQPCF-HGGTCEATAGSPLGFICHCPKGF 1079
Score = 111 bits (267), Expect = 6e-24
Identities = 118/414 (28%), Positives = 161/414 (38%), Gaps = 67/414 (16%)
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNT--------------AGSF 225
G TC C PG+ + C D C N LC+ GG C SF
Sbjct: 47 GQGTCQCAPGF----LGETCQFPDPC-QNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSF 101
Query: 226 RCECGHGMELAPDRLSCKDIDECSITSGICSN-GACENQM-GTYQCVCDEGYAQSTVKSH 283
C C G +R K D C CS G C Q G QC C G+ +
Sbjct: 102 LCTCLPGF--TGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR 157
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGG- 341
C+ T C C G+ +G +C RD++EC PC G
Sbjct: 158 DFCSANPCVNGG----VCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGT 209
Query: 342 QCRNTVGSYTCTCTDGLV-PSA---AGAKP--------TCQDIDECADLISTIIM---MS 386
C NT+GS+ C C G P AG P TCQ + E +
Sbjct: 210 SCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Query: 387 VDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECEL-GTC 443
+ + + D + C G+C + + ++ C CP+ ++ G C++D DECE G
Sbjct: 270 GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT-----GWDCSEDVDECETQGPP 324
Query: 444 DCHPAADCINLPGSFQCRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCL 502
C C N GSF C C GW G +CE+ +D+C+ C P +TC + GSF CL
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLDDCIAAT--CAPGSTCIDRVGSFSCL 380
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG--GYECDCDV 554
C G G L +C C +C+ +P L + C PG G C D+
Sbjct: 381 CPPGRTGLLCHLEDMCLSQPCHGDAQCSTNP-LTGSTLCLCQPGYSGPTCHQDL 433
Score = 108 bits (259), Expect = 6e-23
Identities = 108/436 (24%), Positives = 163/436 (37%), Gaps = 70/436 (16%)
Query: 129 CGHGRCRNLLGGFTCDC-FPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
C HG C+ CD + G E +++ C+ C G C+ + C C
Sbjct: 667 CHHGHCQR--SSCVCDVGWTGPECEAELGGCISA-PC------AHGGTCYPQPSGYNCTC 717
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDE 247
GY S+ ++ C L GG C + G + C C P C+ +
Sbjct: 718 PTGYTGPTCSE---EMTACHSGPCL-NGGSCNPSPGGYYCTCPPS-HTGPQ---CQTSTD 769
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
+++ + G C N+ GT+ C+C G+ + R +C ++P
Sbjct: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA--TCQDSPQG 827
Query: 308 YHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGA 365
C C + G SC+ + D CA +PC C T S+ C C G
Sbjct: 828 PRCLCPTVY----TGGSCQTLMDLCA--QKPCPRNSHCLQTGPSFHCLCLQGWTG----- 876
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSV 424
P C + + S + S + LC G C ++ S+ C CP G+
Sbjct: 877 -PLCN-----------LPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-- 922
Query: 425 KPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTN 482
QG C D + CE + C A C+ P + C+C G+ DG C +++D C +
Sbjct: 923 ---QGSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPGY--DGQNCSKELDACQSQ 975
Query: 483 NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT-LCENGHC 541
CH TC G F C C G+ GLR C D+DEC + P C
Sbjct: 976 P--CHNHGTCTPKPGGFHCACPPGF----VGLR---CE---GDVDECLDQPCHPTGTAAC 1023
Query: 542 SNTPGGYECDCDVGFT 557
+ + C C G T
Sbjct: 1024 HSLANAFYCQCLPGHT 1039
Score = 73.3 bits (172), Expect = 2e-12
Identities = 115/474 (24%), Positives = 161/474 (33%), Gaps = 82/474 (17%)
Query: 131 HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN------TEGSFT 184
+ C F C C G+ N + + G+ CHN + S+
Sbjct: 856 NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF 915
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC-K 243
CHC PG++ +C D ++ G C+ + C+C G D +C K
Sbjct: 916 CHCPPGFQGS----LCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY----DGQNCSK 967
Query: 244 DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
++D C S C N G C + G + C C G+ + +C
Sbjct: 968 ELDACQ--SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTA-ACH 1024
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGS---YTCTCTDG 357
+ +++C C G H G+ C +ID C ++PC GG C T GS + C C G
Sbjct: 1025 SLANAFYCQCLPG-HT---GQWCEVEIDPCH--SQPCFHGGTCEATAGSPLGFICHCPKG 1078
Query: 358 LV-PSAAGAKPTCQDIDEC-----------ADLISTIIMMSVDELQKSVDPQIPELCGA- 404
P+ + P+C C +S + P P+ CG
Sbjct: 1079 FEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 1137
Query: 405 ------GSCHNTIG----SFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADCIN 453
GSC T G F C CP Q P + G CD + N
Sbjct: 1138 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1197
Query: 454 LPGSFQCRCR--DGWRGDGATCEDVDEC--LTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G C D W+G C C L +G CHP+ S CL D
Sbjct: 1198 WDGG-DCSLGVPDPWKG----CPSHSRCWLLFRDGQCHPQCD------SEECLFD----- 1241
Query: 510 DGYGLRTV-CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADG 562
GY T C + D+ +D NGHC EC D G R DG
Sbjct: 1242 -GYDCETPPACTPA---YDQYCHDHF--HNGHCEKGCNTAECGWDGGDCRPEDG 1289
Score = 72.1 bits (169), Expect = 5e-12
Identities = 70/253 (27%), Positives = 98/253 (38%), Gaps = 34/253 (13%)
Query: 331 CAGGARPCG-GGQCRN-TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
C PC GG C + ++G TC C G + CQ+ C + S ++
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
Query: 389 -ELQKSVDPQIPE-LCGAGSCHNTIGSFVCQ------CPDGY-------SVKPEQGPACT 433
L S P P LC +C CQ CP + ++ P C+
Sbjct: 88 LGLPSSPSPLTPSFLC---TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCS 144
Query: 434 -----DDDECEL-GTCDCHPAAD---CINLPGSFQCRCRDGWRGDGATCE-DVDECLTNN 483
++C+L C +P + C+ QC C G+ +G CE DV+EC +
Sbjct: 145 CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF--EGHACERDVNECFQDP 202
Query: 484 GGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT-VCCVYSCVDIDECANDPTLCENGH-C 541
G C +C NT GSF+CLC G +G LR C C + C P H C
Sbjct: 203 GPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLC 262
Query: 542 SNTPGGYECDCDV 554
PG DC+V
Sbjct: 263 LCPPGFIGPDCEV 275
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 155 bits (376), Expect = 4e-37
Identities = 144/463 (31%), Positives = 193/463 (41%), Gaps = 95/463 (20%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC PG C G C N LG F C C G E CE+ G C
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGP----------RCELRAGPCPPR 241
Query: 175 DCHN---------TEGSF-TCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGS 224
C N + +F C C PG+ D V+ D C + GG C + +
Sbjct: 242 GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---VNPDNCVSHQCQ-NGGTCQDGLDT 297
Query: 225 FRCECGHGMELAPDRLSCKDIDECSITSG--ICSN-GACENQMGTYQCVCDEGYAQSTVK 281
+ C C E +D+DEC T G C N G C+N G++ CVC G+ ++ +
Sbjct: 298 YTCLC---PETWTGWDCSEDVDECE-TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE 353
Query: 282 SHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GG 340
+ +C++ GS+ C C G G C D C ++PC G
Sbjct: 354 ENLDDCIAATCAPG---STCIDRVGSFSCLCPPG----RTGLLCHLEDMCL--SQPCHGD 404
Query: 341 GQCRNT--VGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDELQKSVDPQ 397
QC GS C C G + PTC QD+DEC +M+ Q
Sbjct: 405 AQCSTNPLTGSTLCLCQPGY------SGPTCHQDLDEC--------LMA---------QQ 441
Query: 398 IPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLP 455
P C GSC NT GSF C CP GY+ G C D +EC + CHP + C++L
Sbjct: 442 GPSPCEHGGSCLNTPGSFNCLCPPGYT-----GSRCEADHNECL--SQPCHPGSTCLDLL 494
Query: 456 GSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+F C C G +G CE + +EC + C A C + F+C+C G+ G
Sbjct: 495 ATFHCLCPPGL--EGQLCEVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSG----- 545
Query: 515 RTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
T C DIDEC + P C N G C + PG + C C GF
Sbjct: 546 -TRC----EEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF 581
Score = 135 bits (326), Expect = 5e-31
Identities = 131/448 (29%), Positives = 175/448 (39%), Gaps = 78/448 (17%)
Query: 126 PGLCG-HGRCRNLLGGFT-CDCFPGY--EKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
P C GRC G C C PG+ E+ C N C V+G G C T
Sbjct: 124 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-SANPC--VNG----GVCLATYP 176
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRL 240
CHC PG++ + D++EC + C +G C NT GSF+C C G E L
Sbjct: 177 QIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCEL 233
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH- 299
++G E + C+C G+ + + +CQ+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSH-----QCQNG 288
Query: 300 -SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARP-C-GGGQCRNTVGSYTCTCT 355
+C + +Y C C E W G C D+DEC P C GG C+N+ GS+ C C
Sbjct: 289 GTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSF 414
G G +++D+C I C GS C + +GSF
Sbjct: 345 SGW-----GGTSCEENLDDC----------------------IAATCAPGSTCIDRVGSF 377
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP--GSFQCRCRDGWRGDGAT 472
C CP G + G C +D C + CH A C P GS C C+ G+ G T
Sbjct: 378 SCLCPPGRT-----GLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLCQPGY--SGPT 428
Query: 473 C-EDVDECLTNNGG---CHPRATCANTDGSFRCLCDTGYKGDGYGL-RTVCCVYSCVDID 527
C +D+DECL G C +C NT GSF CLC GY G C C
Sbjct: 429 CHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488
Query: 528 ECANDPTLCENGHCSNTPG--GYECDCD 553
C + L HC PG G C+ +
Sbjct: 489 TCLD---LLATFHCLCPPGLEGQLCEVE 513
Score = 133 bits (321), Expect = 2e-30
Identities = 127/447 (28%), Positives = 175/447 (39%), Gaps = 87/447 (19%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++E NECA+ P L H C +LL GF C C PG+ S D++EC G G
Sbjct: 511 EVETNECASAPCL-NHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRSSPCANG-GQ 565
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C + G+F C C PG++ + ++DEC +D G C++ G+F C C G
Sbjct: 566 CQDQPGAFHCKCLPGFEGP---RCQTEVDECL-SDPCPVGASCLDLPGAFFCLCPSGFT- 620
Query: 236 APDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+L C ++ C+ +C C++Q C+C +G
Sbjct: 621 --GQL-C-EVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHG---- 670
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTC 352
CQ S C C GW G C ++ C PC GG C Y C
Sbjct: 671 -HCQRSS--------CVCDVGW----TGPECEAELGGCISA--PCAHGGTCYPQPSGYNC 715
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
TC G PTC + + + P L G GSC+ + G
Sbjct: 716 TCPTGYTG------PTCSE-------------------EMTACHSGPCLNG-GSCNPSPG 749
Query: 413 SFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
+ C CP ++ GP C T D C + C C+N PG+F C C G++G
Sbjct: 750 GYYCTCPPSHT-----GPQCQTSTDYCV--SAPCFNGGTCVNRPGTFSCLCAMGFQGP-- 800
Query: 472 TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI-DECA 530
CE + C RATC ++ RCLC T Y G SC + D CA
Sbjct: 801 RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYTGG-----------SCQTLMDLCA 849
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFT 557
P N HC T + C C G+T
Sbjct: 850 QKP-CPRNSHCLQTGPSFHCLCLQGWT 875
Score = 126 bits (305), Expect = 2e-28
Identities = 122/442 (27%), Positives = 177/442 (40%), Gaps = 57/442 (12%)
Query: 126 PGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSF 183
P C HG C N G F C C PGY + + D NEC + C G C + +F
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGY---TGSRCEADHNEC--LSQPCHPGSTCLDLLATF 497
Query: 184 TCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC 242
C C PG + ++C V+ +ECA L C + F+C C G + R
Sbjct: 498 HCLCPPGLEG----QLCEVETNECASAPCLNHAD-CHDLLNGFQCICLPGF--SGTRCE- 549
Query: 243 KDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
+DIDEC S C+NG C++Q G + C C G+ ++ SC
Sbjct: 550 EDIDECR--SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGA---SC 604
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVP 360
++ PG++ C C G+ G+ C ++ CA C Q C++ C C DG P
Sbjct: 605 LDLPGAFFCLCPSGF----TGQLC-EVPLCAPNL--CQPKQICKDQKDKANCLCPDGS-P 656
Query: 361 SAAGAKPTCQDIDECADLISTI--IMMSVDELQKSVDPQIPELCG-AGSCHNTIGSFVCQ 417
A + C S + + + E + + I C G+C+ + C
Sbjct: 657 GCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCT 716
Query: 418 CPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-D 475
CP GY+ GP C+++ C G C C PG + C C G C+
Sbjct: 717 CPTGYT-----GPTCSEEMTACHSGPC--LNGGSCNPSPGGYYCTCPPSHTGP--QCQTS 767
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
D C++ C TC N G+F CLC G++G + SC D C N T
Sbjct: 768 TDYCVS--APCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK---LRPSCAD-SPCRNRAT- 820
Query: 536 CENGHCSNTPGGYECDCDVGFT 557
C ++P G C C +T
Sbjct: 821 -----CQDSPQGPRCLCPTVYT 837
Score = 114 bits (274), Expect = 9e-25
Identities = 126/459 (27%), Positives = 172/459 (37%), Gaps = 86/459 (18%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVC-G 172
+ E+ C + P C HG C G+ C C GY TC + + C G C
Sbjct: 689 EAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEMTACH--SGPCLN 740
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
G C+ + G + C C P + D C GG CVN G+F C C G
Sbjct: 741 GGSCNPSPGGYYCTCPPSHTGPQCQ---TSTDYCVSAPCF-NGGTCVNRPGTFSCLCAMG 796
Query: 233 MELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ P C+ S C N A C++ +C+C Y + ++
Sbjct: 797 FQ-GP---RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYTGGSCQT--LMDLCAQ 850
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWH---LRADGRSCRD--IDECAGGARPC-GGGQCRN 345
R H C+ T S+HC C +GW SC+ + + + C GG C +
Sbjct: 851 KPCPRNSH-CLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVD 909
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
+ SY C C G S CQD V+P C G
Sbjct: 910 SGPSYFCHCPPGFQGS------LCQD---------------------HVNPCESRPCQNG 942
Query: 406 -SCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCR 463
+C ++CQC GY G C+ + D C+ + CH C PG F C C
Sbjct: 943 ATCMAQPSGYLCQCAPGY-----DGQNCSKELDACQ--SQPCHNHGTCTPKPGGFHCACP 995
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRAT--CANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ G CE DVDECL + CHP T C + +F C C G+ G
Sbjct: 996 PGF--VGLRCEGDVDECL--DQPCHPTGTAACHSLANAFYCQCLPGHTGQ---------- 1041
Query: 521 YSCVDIDECANDPTLCENGHCSNTPG---GYECDCDVGF 556
+ V+ID C + P G C T G G+ C C GF
Sbjct: 1042 WCEVEIDPCHSQPCF-HGGTCEATAGSPLGFICHCPKGF 1079
Score = 111 bits (267), Expect = 6e-24
Identities = 118/414 (28%), Positives = 161/414 (38%), Gaps = 67/414 (16%)
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNT--------------AGSF 225
G TC C PG+ + C D C N LC+ GG C SF
Sbjct: 47 GQGTCQCAPGF----LGETCQFPDPC-QNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSF 101
Query: 226 RCECGHGMELAPDRLSCKDIDECSITSGICSN-GACENQM-GTYQCVCDEGYAQSTVKSH 283
C C G +R K D C CS G C Q G QC C G+ +
Sbjct: 102 LCTCLPGF--TGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR 157
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGG- 341
C+ T C C G+ +G +C RD++EC PC G
Sbjct: 158 DFCSANPCVNGG----VCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGT 209
Query: 342 QCRNTVGSYTCTCTDGLV-PSA---AGAKP--------TCQDIDECADLISTIIM---MS 386
C NT+GS+ C C G P AG P TCQ + E +
Sbjct: 210 SCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Query: 387 VDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECEL-GTC 443
+ + + D + C G+C + + ++ C CP+ ++ G C++D DECE G
Sbjct: 270 GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT-----GWDCSEDVDECETQGPP 324
Query: 444 DCHPAADCINLPGSFQCRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCL 502
C C N GSF C C GW G +CE+ +D+C+ C P +TC + GSF CL
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLDDCIAAT--CAPGSTCIDRVGSFSCL 380
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG--GYECDCDV 554
C G G L +C C +C+ +P L + C PG G C D+
Sbjct: 381 CPPGRTGLLCHLEDMCLSQPCHGDAQCSTNP-LTGSTLCLCQPGYSGPTCHQDL 433
Score = 108 bits (259), Expect = 6e-23
Identities = 108/436 (24%), Positives = 163/436 (37%), Gaps = 70/436 (16%)
Query: 129 CGHGRCRNLLGGFTCDC-FPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
C HG C+ CD + G E +++ C+ C G C+ + C C
Sbjct: 667 CHHGHCQR--SSCVCDVGWTGPECEAELGGCISA-PC------AHGGTCYPQPSGYNCTC 717
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDE 247
GY S+ ++ C L GG C + G + C C P C+ +
Sbjct: 718 PTGYTGPTCSE---EMTACHSGPCL-NGGSCNPSPGGYYCTCPPS-HTGPQ---CQTSTD 769
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
+++ + G C N+ GT+ C+C G+ + R +C ++P
Sbjct: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA--TCQDSPQG 827
Query: 308 YHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGA 365
C C + G SC+ + D CA +PC C T S+ C C G
Sbjct: 828 PRCLCPTVY----TGGSCQTLMDLCA--QKPCPRNSHCLQTGPSFHCLCLQGWTG----- 876
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSV 424
P C + + S + S + LC G C ++ S+ C CP G+
Sbjct: 877 -PLCN-----------LPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-- 922
Query: 425 KPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTN 482
QG C D + CE + C A C+ P + C+C G+ DG C +++D C +
Sbjct: 923 ---QGSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPGY--DGQNCSKELDACQSQ 975
Query: 483 NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT-LCENGHC 541
CH TC G F C C G+ GLR C D+DEC + P C
Sbjct: 976 P--CHNHGTCTPKPGGFHCACPPGF----VGLR---CE---GDVDECLDQPCHPTGTAAC 1023
Query: 542 SNTPGGYECDCDVGFT 557
+ + C C G T
Sbjct: 1024 HSLANAFYCQCLPGHT 1039
Score = 73.3 bits (172), Expect = 2e-12
Identities = 115/474 (24%), Positives = 161/474 (33%), Gaps = 82/474 (17%)
Query: 131 HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN------TEGSFT 184
+ C F C C G+ N + + G+ CHN + S+
Sbjct: 856 NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF 915
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC-K 243
CHC PG++ +C D ++ G C+ + C+C G D +C K
Sbjct: 916 CHCPPGFQGS----LCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY----DGQNCSK 967
Query: 244 DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
++D C S C N G C + G + C C G+ + +C
Sbjct: 968 ELDACQ--SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTA-ACH 1024
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGS---YTCTCTDG 357
+ +++C C G H G+ C +ID C ++PC GG C T GS + C C G
Sbjct: 1025 SLANAFYCQCLPG-HT---GQWCEVEIDPCH--SQPCFHGGTCEATAGSPLGFICHCPKG 1078
Query: 358 LV-PSAAGAKPTCQDIDEC-----------ADLISTIIMMSVDELQKSVDPQIPELCGA- 404
P+ + P+C C +S + P P+ CG
Sbjct: 1079 FEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 1137
Query: 405 ------GSCHNTIG----SFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADCIN 453
GSC T G F C CP Q P + G CD + N
Sbjct: 1138 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1197
Query: 454 LPGSFQCRCR--DGWRGDGATCEDVDEC--LTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G C D W+G C C L +G CHP+ S CL D
Sbjct: 1198 WDGG-DCSLGVPDPWKG----CPSHSRCWLLFRDGQCHPQCD------SEECLFD----- 1241
Query: 510 DGYGLRTV-CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADG 562
GY T C + D+ +D NGHC EC D G R DG
Sbjct: 1242 -GYDCETPPACTPA---YDQYCHDHF--HNGHCEKGCNTAECGWDGGDCRPEDG 1289
Score = 72.1 bits (169), Expect = 5e-12
Identities = 70/253 (27%), Positives = 98/253 (38%), Gaps = 34/253 (13%)
Query: 331 CAGGARPCG-GGQCRN-TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
C PC GG C + ++G TC C G + CQ+ C + S ++
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
Query: 389 -ELQKSVDPQIPE-LCGAGSCHNTIGSFVCQ------CPDGY-------SVKPEQGPACT 433
L S P P LC +C CQ CP + ++ P C+
Sbjct: 88 LGLPSSPSPLTPSFLC---TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCS 144
Query: 434 -----DDDECEL-GTCDCHPAAD---CINLPGSFQCRCRDGWRGDGATCE-DVDECLTNN 483
++C+L C +P + C+ QC C G+ +G CE DV+EC +
Sbjct: 145 CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF--EGHACERDVNECFQDP 202
Query: 484 GGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT-VCCVYSCVDIDECANDPTLCENGH-C 541
G C +C NT GSF+CLC G +G LR C C + C P H C
Sbjct: 203 GPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLC 262
Query: 542 SNTPGGYECDCDV 554
PG DC+V
Sbjct: 263 LCPPGFIGPDCEV 275
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 155 bits (376), Expect = 4e-37
Identities = 144/463 (31%), Positives = 193/463 (41%), Gaps = 95/463 (20%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC PG C G C N LG F C C G E CE+ G C
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGP----------RCELRAGPCPPR 241
Query: 175 DCHN---------TEGSF-TCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGS 224
C N + +F C C PG+ D V+ D C + GG C + +
Sbjct: 242 GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---VNPDNCVSHQCQ-NGGTCQDGLDT 297
Query: 225 FRCECGHGMELAPDRLSCKDIDECSITSG--ICSN-GACENQMGTYQCVCDEGYAQSTVK 281
+ C C E +D+DEC T G C N G C+N G++ CVC G+ ++ +
Sbjct: 298 YTCLC---PETWTGWDCSEDVDECE-TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE 353
Query: 282 SHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GG 340
+ +C++ GS+ C C G G C D C ++PC G
Sbjct: 354 ENLDDCIAATCAPG---STCIDRVGSFSCLCPPG----RTGLLCHLEDMCL--SQPCHGD 404
Query: 341 GQCRNT--VGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDELQKSVDPQ 397
QC GS C C G + PTC QD+DEC +M+ Q
Sbjct: 405 AQCSTNPLTGSTLCLCQPGY------SGPTCHQDLDEC--------LMA---------QQ 441
Query: 398 IPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLP 455
P C GSC NT GSF C CP GY+ G C D +EC + CHP + C++L
Sbjct: 442 GPSPCEHGGSCLNTPGSFNCLCPPGYT-----GSRCEADHNECL--SQPCHPGSTCLDLL 494
Query: 456 GSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
+F C C G +G CE + +EC + C A C + F+C+C G+ G
Sbjct: 495 ATFHCLCPPGL--EGQLCEVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSG----- 545
Query: 515 RTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
T C DIDEC + P C N G C + PG + C C GF
Sbjct: 546 -TRC----EEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF 581
Score = 145 bits (351), Expect = 4e-34
Identities = 135/465 (29%), Positives = 192/465 (41%), Gaps = 70/465 (15%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGV-CGDGD-CHNTEGSFTCHCRP 189
G C++ L +TC C P E + DV+ECE C +G C N+ GSF C C
Sbjct: 289 GTCQDGLDTYTCLC-P--ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVS 345
Query: 190 GYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC 248
G+ + ++D+C A C G C++ GSF C C G L C D C
Sbjct: 346 GWGGTSCEE---NLDDCIA--ATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC 396
Query: 249 SITSGICSNGACENQ--MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SCVNT 304
++ + C G+ C+C GY+ T C+H SC+NT
Sbjct: 397 -LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 305 PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTCTDGL---- 358
PGS++C C G+ G C D +EC ++PC G C + + ++ C C GL
Sbjct: 456 PGSFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPGLEGQL 509
Query: 359 --VPSAAGAKPTCQDIDECADLISTIIMM-----SVDELQKSVDPQIPELCG-AGSCHNT 410
V + A C + +C DL++ + S ++ +D C G C +
Sbjct: 510 CEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQ 569
Query: 411 IGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
G+F C+C G+ +GP C T+ DEC C A C++LPG+F C C G+ G
Sbjct: 570 PGAFHCKCLPGF-----EGPRCQTEVDECLSDPCPV--GASCLDLPGAFFCLCPSGFTGQ 622
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY------SC 523
CE V C N C P+ C + CLC G G C + SC
Sbjct: 623 --LCE-VPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 524 V-DI----DECANDPTLC------ENGHCSNTPGGYECDCDVGFT 557
V D+ EC + C G C P GY C C G+T
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 722
Score = 139 bits (336), Expect = 3e-32
Identities = 128/464 (27%), Positives = 181/464 (39%), Gaps = 75/464 (16%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++E NECA+ P L H C +LL GF C C PG+ S D++EC G G
Sbjct: 511 EVETNECASAPCL-NHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRSSPCANG-GQ 565
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME- 234
C + G+F C C PG++ + ++DEC +D G C++ G+F C C G
Sbjct: 566 CQDQPGAFHCKCLPGFEG---PRCQTEVDECL-SDPCPVGASCLDLPGAFFCLCPSGFTG 621
Query: 235 -------LAPDRLSCKDI--DECSITSGICSNGACENQMGTYQCVCDEGYAQSTV----- 280
AP+ K I D+ + +C +G+ C C G+ Q +
Sbjct: 622 QLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDV 681
Query: 281 --KSHXXXXXXXXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGA 335
C H +C P Y+CTC G+ G +C ++ C G
Sbjct: 682 GWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSG- 736
Query: 336 RPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV 394
PC GG C + G Y CTC PS G P C Q S
Sbjct: 737 -PCLNGGSCNPSPGGYYCTCP----PSHTG--PQC---------------------QTST 768
Query: 395 DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCIN 453
D + C G+C N G+F C C G+ QGP C C A C +
Sbjct: 769 DYCVSAPCFNGGTCVNRPGTFSCLCAMGF-----QGPRCEGKLRPSCADSPCRNRATCQD 823
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
P +C C G+ G +C+ + + L C + C T SF CLC G+ G
Sbjct: 824 SPQGPRCLCPTGY--TGGSCQTLMD-LCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCN 880
Query: 514 LRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
L C + + + + +LC NG C ++ Y C C GF
Sbjct: 881 LPLSSCQKAA--LSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922
Score = 136 bits (330), Expect = 1e-31
Identities = 128/457 (28%), Positives = 179/457 (39%), Gaps = 72/457 (15%)
Query: 130 GHGRCRN--LLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVD---GVCGDG-DCHNTEGS 182
G +C L G C C PGY TC D++EC + C G C NT GS
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGS 458
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLS 241
F C C PGY S+ D +EC C G C++ +F C C G+E +L
Sbjct: 459 FNCLCPPGYTG---SRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE---GQLC 510
Query: 242 CKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+ +EC+ S C N A C + + +QC+C G++ + +
Sbjct: 511 EVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG---Q 565
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C + PG++HC C G+ +G C+ ++DEC P G C + G++ C C G
Sbjct: 566 CQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGAS-CLDLPGAFFCLCPSGFT 620
Query: 360 PSAAG----AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
A CQ C D + D P+ C G C +
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---- 676
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD---CINLPGSFQCRCRDGWRGDGAT 472
C C G++ GP C E ELG C P A C P + C C G+ G T
Sbjct: 677 CVCDVGWT-----GPEC----EAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGP--T 725
Query: 473 C-EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
C E++ C ++G C +C + G + C C + G T CV + C N
Sbjct: 726 CSEEMTAC--HSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA-----PCFN 778
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
G C N PG + C C +GF G C GK
Sbjct: 779 ------GGTCVNRPGTFSCLCAMGF----QGPRCEGK 805
Score = 135 bits (326), Expect = 5e-31
Identities = 131/448 (29%), Positives = 175/448 (39%), Gaps = 78/448 (17%)
Query: 126 PGLCG-HGRCRNLLGGFT-CDCFPGY--EKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
P C GRC G C C PG+ E+ C N C V+G G C T
Sbjct: 124 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-SANPC--VNG----GVCLATYP 176
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRL 240
CHC PG++ + D++EC + C +G C NT GSF+C C G E L
Sbjct: 177 QIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCEL 233
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH- 299
++G E + C+C G+ + + +CQ+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSH-----QCQNG 288
Query: 300 -SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARP-C-GGGQCRNTVGSYTCTCT 355
+C + +Y C C E W G C D+DEC P C GG C+N+ GS+ C C
Sbjct: 289 GTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSF 414
G G +++D+C I C GS C + +GSF
Sbjct: 345 SGW-----GGTSCEENLDDC----------------------IAATCAPGSTCIDRVGSF 377
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP--GSFQCRCRDGWRGDGAT 472
C CP G + G C +D C + CH A C P GS C C+ G+ G T
Sbjct: 378 SCLCPPGRT-----GLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLCQPGY--SGPT 428
Query: 473 C-EDVDECLTNNGG---CHPRATCANTDGSFRCLCDTGYKGDGYGL-RTVCCVYSCVDID 527
C +D+DECL G C +C NT GSF CLC GY G C C
Sbjct: 429 CHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488
Query: 528 ECANDPTLCENGHCSNTPG--GYECDCD 553
C + L HC PG G C+ +
Sbjct: 489 TCLD---LLATFHCLCPPGLEGQLCEVE 513
Score = 118 bits (283), Expect = 7e-26
Identities = 127/459 (27%), Positives = 173/459 (37%), Gaps = 86/459 (18%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVC-G 172
+ E+ C + P C HG C G+ C C GY TC + + C G C
Sbjct: 689 EAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEMTACH--SGPCLN 740
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
G C+ + G + C C P + D C GG CVN G+F C C G
Sbjct: 741 GGSCNPSPGGYYCTCPPSHTGPQCQ---TSTDYCVSAPCF-NGGTCVNRPGTFSCLCAMG 796
Query: 233 MELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ P C+ S C N A C++ +C+C GY + ++
Sbjct: 797 FQ-GP---RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT--LMDLCAQ 850
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWH---LRADGRSCRD--IDECAGGARPC-GGGQCRN 345
R H C+ T S+HC C +GW SC+ + + + C GG C +
Sbjct: 851 KPCPRNSH-CLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVD 909
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
+ SY C C G S CQD V+P C G
Sbjct: 910 SGPSYFCHCPPGFQGS------LCQD---------------------HVNPCESRPCQNG 942
Query: 406 -SCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCR 463
+C ++CQC GY G C+ + D C+ + CH C PG F C C
Sbjct: 943 ATCMAQPSGYLCQCAPGY-----DGQNCSKELDACQ--SQPCHNHGTCTPKPGGFHCACP 995
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRAT--CANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ G CE DVDECL + CHP T C + +F C C G+ G
Sbjct: 996 PGF--VGLRCEGDVDECL--DQPCHPTGTAACHSLANAFYCQCLPGHTGQ---------- 1041
Query: 521 YSCVDIDECANDPTLCENGHCSNTPG---GYECDCDVGF 556
+ V+ID C + P G C T G G+ C C GF
Sbjct: 1042 WCEVEIDPCHSQPCF-HGGTCEATAGSPLGFICHCPKGF 1079
Score = 111 bits (268), Expect = 5e-24
Identities = 109/436 (25%), Positives = 164/436 (37%), Gaps = 70/436 (16%)
Query: 129 CGHGRCRNLLGGFTCDC-FPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
C HG C+ CD + G E +++ C+ C G C+ + C C
Sbjct: 667 CHHGHCQR--SSCVCDVGWTGPECEAELGGCISA-PC------AHGGTCYPQPSGYNCTC 717
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDE 247
GY S+ ++ C L GG C + G + C C P C+ +
Sbjct: 718 PTGYTGPTCSE---EMTACHSGPCL-NGGSCNPSPGGYYCTCPPS-HTGPQ---CQTSTD 769
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
+++ + G C N+ GT+ C+C G+ + R +C ++P
Sbjct: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA--TCQDSPQG 827
Query: 308 YHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGA 365
C C G+ G SC+ + D CA +PC C T S+ C C G
Sbjct: 828 PRCLCPTGY----TGGSCQTLMDLCA--QKPCPRNSHCLQTGPSFHCLCLQGWTG----- 876
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSV 424
P C + + S + S + LC G C ++ S+ C CP G+
Sbjct: 877 -PLCN-----------LPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-- 922
Query: 425 KPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTN 482
QG C D + CE + C A C+ P + C+C G+ DG C +++D C +
Sbjct: 923 ---QGSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPGY--DGQNCSKELDACQSQ 975
Query: 483 NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT-LCENGHC 541
CH TC G F C C G+ GLR C D+DEC + P C
Sbjct: 976 P--CHNHGTCTPKPGGFHCACPPGF----VGLR---CE---GDVDECLDQPCHPTGTAAC 1023
Query: 542 SNTPGGYECDCDVGFT 557
+ + C C G T
Sbjct: 1024 HSLANAFYCQCLPGHT 1039
Score = 111 bits (267), Expect = 6e-24
Identities = 118/414 (28%), Positives = 161/414 (38%), Gaps = 67/414 (16%)
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNT--------------AGSF 225
G TC C PG+ + C D C N LC+ GG C SF
Sbjct: 47 GQGTCQCAPGF----LGETCQFPDPC-QNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSF 101
Query: 226 RCECGHGMELAPDRLSCKDIDECSITSGICSN-GACENQM-GTYQCVCDEGYAQSTVKSH 283
C C G +R K D C CS G C Q G QC C G+ +
Sbjct: 102 LCTCLPGF--TGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR 157
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGG- 341
C+ T C C G+ +G +C RD++EC PC G
Sbjct: 158 DFCSANPCVNGG----VCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGT 209
Query: 342 QCRNTVGSYTCTCTDGLV-PSA---AGAKP--------TCQDIDECADLISTIIM---MS 386
C NT+GS+ C C G P AG P TCQ + E +
Sbjct: 210 SCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Query: 387 VDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECEL-GTC 443
+ + + D + C G+C + + ++ C CP+ ++ G C++D DECE G
Sbjct: 270 GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT-----GWDCSEDVDECETQGPP 324
Query: 444 DCHPAADCINLPGSFQCRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCL 502
C C N GSF C C GW G +CE+ +D+C+ C P +TC + GSF CL
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLDDCIAAT--CAPGSTCIDRVGSFSCL 380
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG--GYECDCDV 554
C G G L +C C +C+ +P L + C PG G C D+
Sbjct: 381 CPPGRTGLLCHLEDMCLSQPCHGDAQCSTNP-LTGSTLCLCQPGYSGPTCHQDL 433
Score = 73.3 bits (172), Expect = 2e-12
Identities = 115/474 (24%), Positives = 161/474 (33%), Gaps = 82/474 (17%)
Query: 131 HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN------TEGSFT 184
+ C F C C G+ N + + G+ CHN + S+
Sbjct: 856 NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF 915
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC-K 243
CHC PG++ +C D ++ G C+ + C+C G D +C K
Sbjct: 916 CHCPPGFQGS----LCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY----DGQNCSK 967
Query: 244 DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
++D C S C N G C + G + C C G+ + +C
Sbjct: 968 ELDACQ--SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTA-ACH 1024
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGS---YTCTCTDG 357
+ +++C C G H G+ C +ID C ++PC GG C T GS + C C G
Sbjct: 1025 SLANAFYCQCLPG-HT---GQWCEVEIDPCH--SQPCFHGGTCEATAGSPLGFICHCPKG 1078
Query: 358 LV-PSAAGAKPTCQDIDEC-----------ADLISTIIMMSVDELQKSVDPQIPELCGA- 404
P+ + P+C C +S + P P+ CG
Sbjct: 1079 FEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 1137
Query: 405 ------GSCHNTIG----SFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADCIN 453
GSC T G F C CP Q P + G CD + N
Sbjct: 1138 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1197
Query: 454 LPGSFQCRCR--DGWRGDGATCEDVDEC--LTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G C D W+G C C L +G CHP+ S CL D
Sbjct: 1198 WDGG-DCSLGVPDPWKG----CPSHSRCWLLFRDGQCHPQCD------SEECLFD----- 1241
Query: 510 DGYGLRTV-CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADG 562
GY T C + D+ +D NGHC EC D G R DG
Sbjct: 1242 -GYDCETPPACTPA---YDQYCHDHF--HNGHCEKGCNTAECGWDGGDCRPEDG 1289
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/230 (27%), Positives = 87/230 (37%), Gaps = 37/230 (16%)
Query: 331 CAGGARPCG-GGQCRN-TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
C PC GG C + ++G TC C G + CQ+ C + S ++
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
Query: 389 -ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
L S P P SF+C C G++ + Q +D C C
Sbjct: 88 LGLPSSPSPLTP-------------SFLCTCLPGFTGERCQAKL---EDPCPPSFCSKRG 131
Query: 448 AADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
I G QC C GW G+ C+ D C N C C T +C C G+
Sbjct: 132 RCH-IQASGRPQCSCMPGWTGE--QCQLRDFCSANP--CVNGGVCLATYPQIQCHCPPGF 186
Query: 508 KGDGYGLRTVCCVYSCV-DIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
+G ++C D++EC DP C G C NT G ++C C VG
Sbjct: 187 EG-----------HACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225
>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
protein.
Length = 1214
Score = 155 bits (375), Expect = 5e-37
Identities = 139/498 (27%), Positives = 203/498 (40%), Gaps = 90/498 (18%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GD 173
Q++ NEC A P C + + C+NL+ + CDC PG+ + + +++N+C G C D
Sbjct: 397 QLDANECEAKP--CVNAKSCKNLIASYYCDCLPGWMGQNCD---ININDCL---GQCQND 448
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PGY D + DIDECA N L GG C N F+C C G
Sbjct: 449 ASCRDLVNGYRCICPPGYAGDHCER---DIDECASNPCL-NGGHCQNEINRFQCLCPTGF 504
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDE---GYAQSTVKSHXXXXXX 289
L DID C C NGA C N+ Y C C E G S +K H
Sbjct: 505 S---GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPC 559
Query: 290 XXXXXXRCQHSCVNTP----------------------GSYHCTCREGWHLRADGRSCRD 327
+ +TP G + C C +G+ G C +
Sbjct: 560 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF----TGTYCHE 615
Query: 328 -IDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAG------AKPTCQDIDECADLI 379
I++C + PC GG C + V SY C C+DG + ++ C + C DL+
Sbjct: 616 NINDCE--SNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLV 673
Query: 380 STIIMMSVDELQ----KSVDPQIPEL-CG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
+ + + S D Q E C G+C++ +F C CP G+ +G C
Sbjct: 674 NDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW-----EGTTCN 728
Query: 434 DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCA 493
CH C+ SF C C++GW G ++ ++C + C+ TC
Sbjct: 729 IARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGP-ICAQNTNDCSPH--PCYNSGTCV 785
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDC 552
+ D +RC C G+ G C ++I+EC + P C G C + GY C C
Sbjct: 786 DGDNWYRCECAPGFAGPD------C----RININECQSSP--CAFGATCVDEINGYRCVC 833
Query: 553 DVGFTRA----ADGRSCL 566
G + A GR C+
Sbjct: 834 PPGHSGAKCQEVSGRPCI 851
Score = 137 bits (331), Expect = 1e-31
Identities = 126/458 (27%), Positives = 191/458 (41%), Gaps = 78/458 (17%)
Query: 119 VNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDC 176
+++C+ P C HG C++L+ GF C C P + TC +D NECE V C
Sbjct: 362 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKS-C 414
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCRGGRCVNTAGSFRCECGHGM 233
N S+ C C PG+ + ++I++C NDA CR + +RC C G
Sbjct: 415 KNLIASYYCDCLPGWMGQNCD---ININDCLGQCQNDASCR-----DLVNGYRCICPPGY 466
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A D +DIDEC+ S C NG C+N++ +QC+C G++ + +
Sbjct: 467 --AGDHCE-RDIDECA--SNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ-----LDIDYC 516
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGW------HLRADGRS--CRDIDECAGGARPCGGGQ 342
CQ+ C N Y C C E + HL+ R+ C ID C +
Sbjct: 517 EPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPE 576
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
+ S C G S +G K TC D T ++++ + +
Sbjct: 577 GVRYISSNVCG-PHGKCKSQSGGKFTC---DCNKGFTGTYCHENINDCESN------PCR 626
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCR 461
G+C + + S+ C C DG+ +G C T+ ++C C H C +L F C
Sbjct: 627 NGGTCIDGVNSYKCICSDGW-----EGAYCETNINDCSQNPC--HNGGTCRDLVNDFYCD 679
Query: 462 CRDGWRGDGATCED--VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C++GW+G D DE NNGG TC + +F+C+C G++G T C
Sbjct: 680 CKNGWKGKTCHSRDSQCDEATCNNGG-----TCYDEGDAFKCMCPGGWEG------TTC- 727
Query: 520 VYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
+ C +P C N G C + C C G+
Sbjct: 728 --NIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGW 761
Score = 133 bits (321), Expect = 2e-30
Identities = 121/446 (27%), Positives = 181/446 (40%), Gaps = 57/446 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD 175
E+ E A C G C+ GF C+C PG+ TC ++++C + G
Sbjct: 321 EIAEHACLSDPCHNRGSCKETSLGFECECSPGW----TGPTCSTNIDDCS-PNNCSHGGT 375
Query: 176 CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + F C C P + K C +D +EC + C N S+ C+C G
Sbjct: 376 CQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCV-NAKSCKNLIASYYCDCLPGWM 430
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C +I++C G C N A C + + Y+C+C GYA +
Sbjct: 431 ----GQNCDININDC---LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPC 483
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C N + C C G+ G C+ DID C PC G QC N Y
Sbjct: 484 LNG---GHCQNEINRFQCLCPTGF----SGNLCQLDIDYCE--PNPCQNGAQCYNRASDY 534
Query: 351 TCTCTDGLV-PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCH 408
C C + + + K C+ C + S + M+ ++ + V +CG G C
Sbjct: 535 FCKCPEDYEGKNCSHLKDHCR-TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCK 593
Query: 409 N-TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGW 466
+ + G F C C G++ G C ++ ++CE + C CI+ S++C C DGW
Sbjct: 594 SQSGGKFTCDCNKGFT-----GTYCHENINDCE--SNPCRNGGTCIDGVNSYKCICSDGW 646
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+GA CE ++++C N CH TC + F C C G+KG R C D
Sbjct: 647 --EGAYCETNINDCSQN--PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQC-----D 697
Query: 526 IDECANDPTLCENGHCSN--TPGGYE 549
C N T + G PGG+E
Sbjct: 698 EATCNNGGTCYDEGDAFKCMCPGGWE 723
Score = 109 bits (262), Expect = 3e-23
Identities = 125/456 (27%), Positives = 177/456 (38%), Gaps = 80/456 (17%)
Query: 144 DCFPGYEKDSK-NHTCVDV---NECEIVDGVCGDGDCHNTEGSFT----CHCRPGYKADD 195
D F Y D N TC++ EC +C G C GS C C+ G++
Sbjct: 192 DFFGHYACDQNGNKTCMEGWMGPECN--RAICRQG-CSPKHGSCKLPGDCRCQYGWQG-- 246
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
+ D+C + C G C N CE G +L KD++ C
Sbjct: 247 -----LYCDKCIPHPG-CVHGIC-NEPWQCLCETNWGGQLCD-----KDLNYCGTHQPCL 294
Query: 256 SNGACENQ-MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCRE 314
+ G C N YQC C EGY+ + + SC T + C C
Sbjct: 295 NGGTCSNTGPDKYQCSCPEGYSGPNCE---IAEHACLSDPCHNRGSCKETSLGFECECSP 351
Query: 315 GWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTC-------TDGLVPSAAGA 365
GW G +C +ID+C+ C GG C++ V + C C T L + A
Sbjct: 352 GW----TGPTCSTNIDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 405
Query: 366 KPTCQDIDECADLISTIIMMSVDE-LQKSVDPQIPELCGA----GSCHNTIGSFVCQCPD 420
KP C + C +LI++ + + ++ D I + G SC + + + C CP
Sbjct: 406 KP-CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPP 464
Query: 421 GYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDE 478
GY+ G C D DEC + C C N FQC C G+ G+ C+ D+D
Sbjct: 465 GYA-----GDHCERDIDEC--ASNPCLNGGHCQNEINRFQCLCPTGFSGN--LCQLDIDY 515
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG-LRTVCCVYSCVDIDEC-----AND 532
C N C A C N + C C Y+G L+ C C ID C +ND
Sbjct: 516 CEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASND 573
Query: 533 P---------TLC-ENGHCSNTPGG-YECDCDVGFT 557
+C +G C + GG + CDC+ GFT
Sbjct: 574 TPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 609
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/161 (28%), Positives = 63/161 (39%), Gaps = 23/161 (14%)
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCD-CHPAADCINL-PGSFQCRCRDGWRGDGAT 472
+C P + G D D GT C C N P +QC C +G+ G
Sbjct: 262 ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY--SGPN 319
Query: 473 CEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
CE + CL++ CH R +C T F C C G+ G C +ID+C+
Sbjct: 320 CEIAEHACLSDP--CHNRGSCKETSLGFECECSPGWTG------PTC----STNIDDCS- 366
Query: 532 DPTLCEN-GHCSNTPGGYECDCD---VGFTRAADGRSCLGK 568
P C + G C + G++C C G T D C K
Sbjct: 367 -PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK 406
>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
Length = 1218
Score = 155 bits (375), Expect = 5e-37
Identities = 139/498 (27%), Positives = 203/498 (40%), Gaps = 90/498 (18%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GD 173
Q++ NEC A P C + + C+NL+ + CDC PG+ + + +++N+C G C D
Sbjct: 410 QLDANECEAKP--CVNAKSCKNLIASYYCDCLPGWMGQNCD---ININDCL---GQCQND 461
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PGY D + DIDECA N L GG C N F+C C G
Sbjct: 462 ASCRDLVNGYRCICPPGYAGDHCER---DIDECASNPCL-NGGHCQNEINRFQCLCPTGF 517
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDE---GYAQSTVKSHXXXXXX 289
L DID C C NGA C N+ Y C C E G S +K H
Sbjct: 518 S---GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPC 572
Query: 290 XXXXXXRCQHSCVNTP----------------------GSYHCTCREGWHLRADGRSCRD 327
+ +TP G + C C +G+ G C +
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF----TGTYCHE 628
Query: 328 -IDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAG------AKPTCQDIDECADLI 379
I++C + PC GG C + V SY C C+DG + ++ C + C DL+
Sbjct: 629 NINDCE--SNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 380 STIIMMSVDELQ----KSVDPQIPEL-CG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
+ + + S D Q E C G+C++ +F C CP G+ +G C
Sbjct: 687 NDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW-----EGTTCN 741
Query: 434 DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCA 493
CH C+ SF C C++GW G ++ ++C + C+ TC
Sbjct: 742 IARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGP-ICAQNTNDCSPH--PCYNSGTCV 798
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDC 552
+ D +RC C G+ G C ++I+EC + P C G C + GY C C
Sbjct: 799 DGDNWYRCECAPGFAGPD------C----RININECQSSP--CAFGATCVDEINGYRCVC 846
Query: 553 DVGFTRA----ADGRSCL 566
G + A GR C+
Sbjct: 847 PPGHSGAKCQEVSGRPCI 864
Score = 137 bits (331), Expect = 1e-31
Identities = 126/458 (27%), Positives = 191/458 (41%), Gaps = 78/458 (17%)
Query: 119 VNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDC 176
+++C+ P C HG C++L+ GF C C P + TC +D NECE V C
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKS-C 427
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCRGGRCVNTAGSFRCECGHGM 233
N S+ C C PG+ + ++I++C NDA CR + +RC C G
Sbjct: 428 KNLIASYYCDCLPGWMGQNCD---ININDCLGQCQNDASCR-----DLVNGYRCICPPGY 479
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A D +DIDEC+ S C NG C+N++ +QC+C G++ + +
Sbjct: 480 --AGDHCE-RDIDECA--SNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ-----LDIDYC 529
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGW------HLRADGRS--CRDIDECAGGARPCGGGQ 342
CQ+ C N Y C C E + HL+ R+ C ID C +
Sbjct: 530 EPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPE 589
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
+ S C G S +G K TC D T ++++ + +
Sbjct: 590 GVRYISSNVCG-PHGKCKSQSGGKFTC---DCNKGFTGTYCHENINDCESN------PCR 639
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCR 461
G+C + + S+ C C DG+ +G C T+ ++C C H C +L F C
Sbjct: 640 NGGTCIDGVNSYKCICSDGW-----EGAYCETNINDCSQNPC--HNGGTCRDLVNDFYCD 692
Query: 462 CRDGWRGDGATCED--VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C++GW+G D DE NNGG TC + +F+C+C G++G T C
Sbjct: 693 CKNGWKGKTCHSRDSQCDEATCNNGG-----TCYDEGDAFKCMCPGGWEG------TTC- 740
Query: 520 VYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
+ C +P C N G C + C C G+
Sbjct: 741 --NIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGW 774
Score = 133 bits (321), Expect = 2e-30
Identities = 121/446 (27%), Positives = 181/446 (40%), Gaps = 57/446 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD 175
E+ E A C G C+ GF C+C PG+ TC ++++C + G
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGW----TGPTCSTNIDDCS-PNNCSHGGT 388
Query: 176 CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + F C C P + K C +D +EC + C N S+ C+C G
Sbjct: 389 CQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCV-NAKSCKNLIASYYCDCLPGWM 443
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C +I++C G C N A C + + Y+C+C GYA +
Sbjct: 444 ----GQNCDININDC---LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPC 496
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C N + C C G+ G C+ DID C PC G QC N Y
Sbjct: 497 LNG---GHCQNEINRFQCLCPTGF----SGNLCQLDIDYCE--PNPCQNGAQCYNRASDY 547
Query: 351 TCTCTDGLV-PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCH 408
C C + + + K C+ C + S + M+ ++ + V +CG G C
Sbjct: 548 FCKCPEDYEGKNCSHLKDHCR-TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCK 606
Query: 409 N-TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGW 466
+ + G F C C G++ G C ++ ++CE + C CI+ S++C C DGW
Sbjct: 607 SQSGGKFTCDCNKGFT-----GTYCHENINDCE--SNPCRNGGTCIDGVNSYKCICSDGW 659
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+GA CE ++++C N CH TC + F C C G+KG R C D
Sbjct: 660 --EGAYCETNINDCSQN--PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQC-----D 710
Query: 526 IDECANDPTLCENGHCSN--TPGGYE 549
C N T + G PGG+E
Sbjct: 711 EATCNNGGTCYDEGDAFKCMCPGGWE 736
Score = 109 bits (262), Expect = 3e-23
Identities = 125/456 (27%), Positives = 177/456 (38%), Gaps = 80/456 (17%)
Query: 144 DCFPGYEKDSK-NHTCVDV---NECEIVDGVCGDGDCHNTEGSFT----CHCRPGYKADD 195
D F Y D N TC++ EC +C G C GS C C+ G++
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECN--RAICRQG-CSPKHGSCKLPGDCRCQYGWQG-- 259
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
+ D+C + C G C N CE G +L KD++ C
Sbjct: 260 -----LYCDKCIPHPG-CVHGIC-NEPWQCLCETNWGGQLCD-----KDLNYCGTHQPCL 307
Query: 256 SNGACENQ-MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCRE 314
+ G C N YQC C EGY+ + + SC T + C C
Sbjct: 308 NGGTCSNTGPDKYQCSCPEGYSGPNCE---IAEHACLSDPCHNRGSCKETSLGFECECSP 364
Query: 315 GWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTC-------TDGLVPSAAGA 365
GW G +C +ID+C+ C GG C++ V + C C T L + A
Sbjct: 365 GW----TGPTCSTNIDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418
Query: 366 KPTCQDIDECADLISTIIMMSVDE-LQKSVDPQIPELCGA----GSCHNTIGSFVCQCPD 420
KP C + C +LI++ + + ++ D I + G SC + + + C CP
Sbjct: 419 KP-CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPP 477
Query: 421 GYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDE 478
GY+ G C D DEC + C C N FQC C G+ G+ C+ D+D
Sbjct: 478 GYA-----GDHCERDIDEC--ASNPCLNGGHCQNEINRFQCLCPTGFSGN--LCQLDIDY 528
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG-LRTVCCVYSCVDIDEC-----AND 532
C N C A C N + C C Y+G L+ C C ID C +ND
Sbjct: 529 CEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASND 586
Query: 533 P---------TLC-ENGHCSNTPGG-YECDCDVGFT 557
+C +G C + GG + CDC+ GFT
Sbjct: 587 TPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/161 (28%), Positives = 63/161 (39%), Gaps = 23/161 (14%)
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCD-CHPAADCINL-PGSFQCRCRDGWRGDGAT 472
+C P + G D D GT C C N P +QC C +G+ G
Sbjct: 275 ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY--SGPN 332
Query: 473 CEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
CE + CL++ CH R +C T F C C G+ G C +ID+C+
Sbjct: 333 CEIAEHACLSDP--CHNRGSCKETSLGFECECSPGWTG------PTC----STNIDDCS- 379
Query: 532 DPTLCEN-GHCSNTPGGYECDCD---VGFTRAADGRSCLGK 568
P C + G C + G++C C G T D C K
Sbjct: 380 -PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK 419
>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged
1 protein.
Length = 1218
Score = 155 bits (375), Expect = 5e-37
Identities = 139/498 (27%), Positives = 203/498 (40%), Gaps = 90/498 (18%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GD 173
Q++ NEC A P C + + C+NL+ + CDC PG+ + + +++N+C G C D
Sbjct: 410 QLDANECEAKP--CVNAKSCKNLIASYYCDCLPGWMGQNCD---ININDCL---GQCQND 461
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PGY D + DIDECA N L GG C N F+C C G
Sbjct: 462 ASCRDLVNGYRCICPPGYAGDHCER---DIDECASNPCL-NGGHCQNEINRFQCLCPTGF 517
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDE---GYAQSTVKSHXXXXXX 289
L DID C C NGA C N+ Y C C E G S +K H
Sbjct: 518 S---GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPC 572
Query: 290 XXXXXXRCQHSCVNTP----------------------GSYHCTCREGWHLRADGRSCRD 327
+ +TP G + C C +G+ G C +
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF----TGTYCHE 628
Query: 328 -IDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAG------AKPTCQDIDECADLI 379
I++C + PC GG C + V SY C C+DG + ++ C + C DL+
Sbjct: 629 NINDCE--SNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 380 STIIMMSVDELQ----KSVDPQIPEL-CG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
+ + + S D Q E C G+C++ +F C CP G+ +G C
Sbjct: 687 NDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW-----EGTTCN 741
Query: 434 DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCA 493
CH C+ SF C C++GW G ++ ++C + C+ TC
Sbjct: 742 IARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGP-ICAQNTNDCSPH--PCYNSGTCV 798
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDC 552
+ D +RC C G+ G C ++I+EC + P C G C + GY C C
Sbjct: 799 DGDNWYRCECAPGFAGPD------C----RININECQSSP--CAFGATCVDEINGYRCVC 846
Query: 553 DVGFTRA----ADGRSCL 566
G + A GR C+
Sbjct: 847 PPGHSGAKCQEVSGRPCI 864
Score = 137 bits (331), Expect = 1e-31
Identities = 126/458 (27%), Positives = 191/458 (41%), Gaps = 78/458 (17%)
Query: 119 VNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDC 176
+++C+ P C HG C++L+ GF C C P + TC +D NECE V C
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKS-C 427
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCRGGRCVNTAGSFRCECGHGM 233
N S+ C C PG+ + ++I++C NDA CR + +RC C G
Sbjct: 428 KNLIASYYCDCLPGWMGQNCD---ININDCLGQCQNDASCR-----DLVNGYRCICPPGY 479
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A D +DIDEC+ S C NG C+N++ +QC+C G++ + +
Sbjct: 480 --AGDHCE-RDIDECA--SNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ-----LDIDYC 529
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGW------HLRADGRS--CRDIDECAGGARPCGGGQ 342
CQ+ C N Y C C E + HL+ R+ C ID C +
Sbjct: 530 EPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPE 589
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
+ S C G S +G K TC D T ++++ + +
Sbjct: 590 GVRYISSNVCG-PHGKCKSQSGGKFTC---DCNKGFTGTYCHENINDCESN------PCR 639
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCR 461
G+C + + S+ C C DG+ +G C T+ ++C C H C +L F C
Sbjct: 640 NGGTCIDGVNSYKCICSDGW-----EGAYCETNINDCSQNPC--HNGGTCRDLVNDFYCD 692
Query: 462 CRDGWRGDGATCED--VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C++GW+G D DE NNGG TC + +F+C+C G++G T C
Sbjct: 693 CKNGWKGKTCHSRDSQCDEATCNNGG-----TCYDEGDAFKCMCPGGWEG------TTC- 740
Query: 520 VYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
+ C +P C N G C + C C G+
Sbjct: 741 --NIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGW 774
Score = 133 bits (321), Expect = 2e-30
Identities = 121/446 (27%), Positives = 181/446 (40%), Gaps = 57/446 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD 175
E+ E A C G C+ GF C+C PG+ TC ++++C + G
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGW----TGPTCSTNIDDCS-PNNCSHGGT 388
Query: 176 CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + F C C P + K C +D +EC + C N S+ C+C G
Sbjct: 389 CQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCV-NAKSCKNLIASYYCDCLPGWM 443
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C +I++C G C N A C + + Y+C+C GYA +
Sbjct: 444 ----GQNCDININDC---LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPC 496
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C N + C C G+ G C+ DID C PC G QC N Y
Sbjct: 497 LNG---GHCQNEINRFQCLCPTGF----SGNLCQLDIDYCE--PNPCQNGAQCYNRASDY 547
Query: 351 TCTCTDGLV-PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCH 408
C C + + + K C+ C + S + M+ ++ + V +CG G C
Sbjct: 548 FCKCPEDYEGKNCSHLKDHCR-TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCK 606
Query: 409 N-TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGW 466
+ + G F C C G++ G C ++ ++CE + C CI+ S++C C DGW
Sbjct: 607 SQSGGKFTCDCNKGFT-----GTYCHENINDCE--SNPCRNGGTCIDGVNSYKCICSDGW 659
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+GA CE ++++C N CH TC + F C C G+KG R C D
Sbjct: 660 --EGAYCETNINDCSQN--PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQC-----D 710
Query: 526 IDECANDPTLCENGHCSN--TPGGYE 549
C N T + G PGG+E
Sbjct: 711 EATCNNGGTCYDEGDAFKCMCPGGWE 736
Score = 109 bits (262), Expect = 3e-23
Identities = 125/456 (27%), Positives = 177/456 (38%), Gaps = 80/456 (17%)
Query: 144 DCFPGYEKDSK-NHTCVDV---NECEIVDGVCGDGDCHNTEGSFT----CHCRPGYKADD 195
D F Y D N TC++ EC +C G C GS C C+ G++
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECN--RAICRQG-CSPKHGSCKLPGDCRCQYGWQG-- 259
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
+ D+C + C G C N CE G +L KD++ C
Sbjct: 260 -----LYCDKCIPHPG-CVHGIC-NEPWQCLCETNWGGQLCD-----KDLNYCGTHQPCL 307
Query: 256 SNGACENQ-MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCRE 314
+ G C N YQC C EGY+ + + SC T + C C
Sbjct: 308 NGGTCSNTGPDKYQCSCPEGYSGPNCE---IAEHACLSDPCHNRGSCKETSLGFECECSP 364
Query: 315 GWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTC-------TDGLVPSAAGA 365
GW G +C +ID+C+ C GG C++ V + C C T L + A
Sbjct: 365 GW----TGPTCSTNIDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418
Query: 366 KPTCQDIDECADLISTIIMMSVDE-LQKSVDPQIPELCGA----GSCHNTIGSFVCQCPD 420
KP C + C +LI++ + + ++ D I + G SC + + + C CP
Sbjct: 419 KP-CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPP 477
Query: 421 GYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDE 478
GY+ G C D DEC + C C N FQC C G+ G+ C+ D+D
Sbjct: 478 GYA-----GDHCERDIDEC--ASNPCLNGGHCQNEINRFQCLCPTGFSGN--LCQLDIDY 528
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG-LRTVCCVYSCVDIDEC-----AND 532
C N C A C N + C C Y+G L+ C C ID C +ND
Sbjct: 529 CEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASND 586
Query: 533 P---------TLC-ENGHCSNTPGG-YECDCDVGFT 557
+C +G C + GG + CDC+ GFT
Sbjct: 587 TPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/161 (28%), Positives = 63/161 (39%), Gaps = 23/161 (14%)
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCD-CHPAADCINL-PGSFQCRCRDGWRGDGAT 472
+C P + G D D GT C C N P +QC C +G+ G
Sbjct: 275 ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY--SGPN 332
Query: 473 CEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
CE + CL++ CH R +C T F C C G+ G C +ID+C+
Sbjct: 333 CEIAEHACLSDP--CHNRGSCKETSLGFECECSPGWTG------PTC----STNIDDCS- 379
Query: 532 DPTLCEN-GHCSNTPGGYECDCD---VGFTRAADGRSCLGK 568
P C + G C + G++C C G T D C K
Sbjct: 380 -PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK 419
>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 155 bits (375), Expect = 5e-37
Identities = 139/498 (27%), Positives = 203/498 (40%), Gaps = 90/498 (18%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GD 173
Q++ NEC A P C + + C+NL+ + CDC PG+ + + +++N+C G C D
Sbjct: 410 QLDANECEAKP--CVNAKSCKNLIASYYCDCLPGWMGQNCD---ININDCL---GQCQND 461
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PGY D + DIDECA N L GG C N F+C C G
Sbjct: 462 ASCRDLVNGYRCICPPGYAGDHCER---DIDECASNPCL-NGGHCQNEINRFQCLCPTGF 517
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDE---GYAQSTVKSHXXXXXX 289
L DID C C NGA C N+ Y C C E G S +K H
Sbjct: 518 S---GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPC 572
Query: 290 XXXXXXRCQHSCVNTP----------------------GSYHCTCREGWHLRADGRSCRD 327
+ +TP G + C C +G+ G C +
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF----TGTYCHE 628
Query: 328 -IDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAG------AKPTCQDIDECADLI 379
I++C + PC GG C + V SY C C+DG + ++ C + C DL+
Sbjct: 629 NINDCE--SNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 380 STIIMMSVDELQ----KSVDPQIPEL-CG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
+ + + S D Q E C G+C++ +F C CP G+ +G C
Sbjct: 687 NDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW-----EGTTCN 741
Query: 434 DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCA 493
CH C+ SF C C++GW G ++ ++C + C+ TC
Sbjct: 742 IARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGP-ICAQNTNDCSPH--PCYNSGTCV 798
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDC 552
+ D +RC C G+ G C ++I+EC + P C G C + GY C C
Sbjct: 799 DGDNWYRCECAPGFAGPD------C----RININECQSSP--CAFGATCVDEINGYRCVC 846
Query: 553 DVGFTRA----ADGRSCL 566
G + A GR C+
Sbjct: 847 PPGHSGAKCQEVSGRPCI 864
Score = 137 bits (331), Expect = 1e-31
Identities = 126/458 (27%), Positives = 191/458 (41%), Gaps = 78/458 (17%)
Query: 119 VNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDC 176
+++C+ P C HG C++L+ GF C C P + TC +D NECE V C
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKS-C 427
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCRGGRCVNTAGSFRCECGHGM 233
N S+ C C PG+ + ++I++C NDA CR + +RC C G
Sbjct: 428 KNLIASYYCDCLPGWMGQNCD---ININDCLGQCQNDASCR-----DLVNGYRCICPPGY 479
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A D +DIDEC+ S C NG C+N++ +QC+C G++ + +
Sbjct: 480 --AGDHCE-RDIDECA--SNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ-----LDIDYC 529
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGW------HLRADGRS--CRDIDECAGGARPCGGGQ 342
CQ+ C N Y C C E + HL+ R+ C ID C +
Sbjct: 530 EPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPE 589
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
+ S C G S +G K TC D T ++++ + +
Sbjct: 590 GVRYISSNVCG-PHGKCKSQSGGKFTC---DCNKGFTGTYCHENINDCESN------PCR 639
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCR 461
G+C + + S+ C C DG+ +G C T+ ++C C H C +L F C
Sbjct: 640 NGGTCIDGVNSYKCICSDGW-----EGAYCETNINDCSQNPC--HNGGTCRDLVNDFYCD 692
Query: 462 CRDGWRGDGATCED--VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C++GW+G D DE NNGG TC + +F+C+C G++G T C
Sbjct: 693 CKNGWKGKTCHSRDSQCDEATCNNGG-----TCYDEGDAFKCMCPGGWEG------TTC- 740
Query: 520 VYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
+ C +P C N G C + C C G+
Sbjct: 741 --NIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGW 774
Score = 133 bits (321), Expect = 2e-30
Identities = 121/446 (27%), Positives = 181/446 (40%), Gaps = 57/446 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD 175
E+ E A C G C+ GF C+C PG+ TC ++++C + G
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGW----TGPTCSTNIDDCS-PNNCSHGGT 388
Query: 176 CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + F C C P + K C +D +EC + C N S+ C+C G
Sbjct: 389 CQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCV-NAKSCKNLIASYYCDCLPGWM 443
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C +I++C G C N A C + + Y+C+C GYA +
Sbjct: 444 ----GQNCDININDC---LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPC 496
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C N + C C G+ G C+ DID C PC G QC N Y
Sbjct: 497 LNG---GHCQNEINRFQCLCPTGF----SGNLCQLDIDYCE--PNPCQNGAQCYNRASDY 547
Query: 351 TCTCTDGLV-PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCH 408
C C + + + K C+ C + S + M+ ++ + V +CG G C
Sbjct: 548 FCKCPEDYEGKNCSHLKDHCR-TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCK 606
Query: 409 N-TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGW 466
+ + G F C C G++ G C ++ ++CE + C CI+ S++C C DGW
Sbjct: 607 SQSGGKFTCDCNKGFT-----GTYCHENINDCE--SNPCRNGGTCIDGVNSYKCICSDGW 659
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+GA CE ++++C N CH TC + F C C G+KG R C D
Sbjct: 660 --EGAYCETNINDCSQN--PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQC-----D 710
Query: 526 IDECANDPTLCENGHCSN--TPGGYE 549
C N T + G PGG+E
Sbjct: 711 EATCNNGGTCYDEGDAFKCMCPGGWE 736
Score = 109 bits (262), Expect = 3e-23
Identities = 125/456 (27%), Positives = 177/456 (38%), Gaps = 80/456 (17%)
Query: 144 DCFPGYEKDSK-NHTCVDV---NECEIVDGVCGDGDCHNTEGSFT----CHCRPGYKADD 195
D F Y D N TC++ EC +C G C GS C C+ G++
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECN--RAICRQG-CSPKHGSCKLPGDCRCQYGWQG-- 259
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
+ D+C + C G C N CE G +L KD++ C
Sbjct: 260 -----LYCDKCIPHPG-CVHGIC-NEPWQCLCETNWGGQLCD-----KDLNYCGTHQPCL 307
Query: 256 SNGACENQ-MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCRE 314
+ G C N YQC C EGY+ + + SC T + C C
Sbjct: 308 NGGTCSNTGPDKYQCSCPEGYSGPNCE---IAEHACLSDPCHNRGSCKETSLGFECECSP 364
Query: 315 GWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTC-------TDGLVPSAAGA 365
GW G +C +ID+C+ C GG C++ V + C C T L + A
Sbjct: 365 GW----TGPTCSTNIDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418
Query: 366 KPTCQDIDECADLISTIIMMSVDE-LQKSVDPQIPELCGA----GSCHNTIGSFVCQCPD 420
KP C + C +LI++ + + ++ D I + G SC + + + C CP
Sbjct: 419 KP-CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPP 477
Query: 421 GYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDE 478
GY+ G C D DEC + C C N FQC C G+ G+ C+ D+D
Sbjct: 478 GYA-----GDHCERDIDEC--ASNPCLNGGHCQNEINRFQCLCPTGFSGN--LCQLDIDY 528
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG-LRTVCCVYSCVDIDEC-----AND 532
C N C A C N + C C Y+G L+ C C ID C +ND
Sbjct: 529 CEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASND 586
Query: 533 P---------TLC-ENGHCSNTPGG-YECDCDVGFT 557
+C +G C + GG + CDC+ GFT
Sbjct: 587 TPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/161 (28%), Positives = 63/161 (39%), Gaps = 23/161 (14%)
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCD-CHPAADCINL-PGSFQCRCRDGWRGDGAT 472
+C P + G D D GT C C N P +QC C +G+ G
Sbjct: 275 ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY--SGPN 332
Query: 473 CEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
CE + CL++ CH R +C T F C C G+ G C +ID+C+
Sbjct: 333 CEIAEHACLSDP--CHNRGSCKETSLGFECECSPGWTG------PTC----STNIDDCS- 379
Query: 532 DPTLCEN-GHCSNTPGGYECDCD---VGFTRAADGRSCLGK 568
P C + G C + G++C C G T D C K
Sbjct: 380 -PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK 419
>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 155 bits (375), Expect = 5e-37
Identities = 139/498 (27%), Positives = 203/498 (40%), Gaps = 90/498 (18%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GD 173
Q++ NEC A P C + + C+NL+ + CDC PG+ + + +++N+C G C D
Sbjct: 410 QLDANECEAKP--CVNAKSCKNLIASYYCDCLPGWMGQNCD---ININDCL---GQCQND 461
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PGY D + DIDECA N L GG C N F+C C G
Sbjct: 462 ASCRDLVNGYRCICPPGYAGDHCER---DIDECASNPCL-NGGHCQNEINRFQCLCPTGF 517
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDE---GYAQSTVKSHXXXXXX 289
L DID C C NGA C N+ Y C C E G S +K H
Sbjct: 518 S---GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPC 572
Query: 290 XXXXXXRCQHSCVNTP----------------------GSYHCTCREGWHLRADGRSCRD 327
+ +TP G + C C +G+ G C +
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF----TGTYCHE 628
Query: 328 -IDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAG------AKPTCQDIDECADLI 379
I++C + PC GG C + V SY C C+DG + ++ C + C DL+
Sbjct: 629 NINDCE--SNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 380 STIIMMSVDELQ----KSVDPQIPEL-CG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
+ + + S D Q E C G+C++ +F C CP G+ +G C
Sbjct: 687 NDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW-----EGTTCN 741
Query: 434 DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCA 493
CH C+ SF C C++GW G ++ ++C + C+ TC
Sbjct: 742 IARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGP-ICAQNTNDCSPH--PCYNSGTCV 798
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDC 552
+ D +RC C G+ G C ++I+EC + P C G C + GY C C
Sbjct: 799 DGDNWYRCECAPGFAGPD------C----RININECQSSP--CAFGATCVDEINGYRCVC 846
Query: 553 DVGFTRA----ADGRSCL 566
G + A GR C+
Sbjct: 847 PPGHSGAKCQEVSGRPCI 864
Score = 137 bits (331), Expect = 1e-31
Identities = 126/458 (27%), Positives = 191/458 (41%), Gaps = 78/458 (17%)
Query: 119 VNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDC 176
+++C+ P C HG C++L+ GF C C P + TC +D NECE V C
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKS-C 427
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCRGGRCVNTAGSFRCECGHGM 233
N S+ C C PG+ + ++I++C NDA CR + +RC C G
Sbjct: 428 KNLIASYYCDCLPGWMGQNCD---ININDCLGQCQNDASCR-----DLVNGYRCICPPGY 479
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A D +DIDEC+ S C NG C+N++ +QC+C G++ + +
Sbjct: 480 --AGDHCE-RDIDECA--SNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ-----LDIDYC 529
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGW------HLRADGRS--CRDIDECAGGARPCGGGQ 342
CQ+ C N Y C C E + HL+ R+ C ID C +
Sbjct: 530 EPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPE 589
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
+ S C G S +G K TC D T ++++ + +
Sbjct: 590 GVRYISSNVCG-PHGKCKSQSGGKFTC---DCNKGFTGTYCHENINDCESN------PCR 639
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCR 461
G+C + + S+ C C DG+ +G C T+ ++C C H C +L F C
Sbjct: 640 NGGTCIDGVNSYKCICSDGW-----EGAYCETNINDCSQNPC--HNGGTCRDLVNDFYCD 692
Query: 462 CRDGWRGDGATCED--VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C++GW+G D DE NNGG TC + +F+C+C G++G T C
Sbjct: 693 CKNGWKGKTCHSRDSQCDEATCNNGG-----TCYDEGDAFKCMCPGGWEG------TTC- 740
Query: 520 VYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
+ C +P C N G C + C C G+
Sbjct: 741 --NIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGW 774
Score = 133 bits (321), Expect = 2e-30
Identities = 121/446 (27%), Positives = 181/446 (40%), Gaps = 57/446 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD 175
E+ E A C G C+ GF C+C PG+ TC ++++C + G
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGW----TGPTCSTNIDDCS-PNNCSHGGT 388
Query: 176 CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + F C C P + K C +D +EC + C N S+ C+C G
Sbjct: 389 CQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCV-NAKSCKNLIASYYCDCLPGWM 443
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C +I++C G C N A C + + Y+C+C GYA +
Sbjct: 444 ----GQNCDININDC---LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPC 496
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C N + C C G+ G C+ DID C PC G QC N Y
Sbjct: 497 LNG---GHCQNEINRFQCLCPTGF----SGNLCQLDIDYCE--PNPCQNGAQCYNRASDY 547
Query: 351 TCTCTDGLV-PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCH 408
C C + + + K C+ C + S + M+ ++ + V +CG G C
Sbjct: 548 FCKCPEDYEGKNCSHLKDHCR-TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCK 606
Query: 409 N-TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGW 466
+ + G F C C G++ G C ++ ++CE + C CI+ S++C C DGW
Sbjct: 607 SQSGGKFTCDCNKGFT-----GTYCHENINDCE--SNPCRNGGTCIDGVNSYKCICSDGW 659
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+GA CE ++++C N CH TC + F C C G+KG R C D
Sbjct: 660 --EGAYCETNINDCSQN--PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQC-----D 710
Query: 526 IDECANDPTLCENGHCSN--TPGGYE 549
C N T + G PGG+E
Sbjct: 711 EATCNNGGTCYDEGDAFKCMCPGGWE 736
Score = 109 bits (262), Expect = 3e-23
Identities = 125/456 (27%), Positives = 177/456 (38%), Gaps = 80/456 (17%)
Query: 144 DCFPGYEKDSK-NHTCVDV---NECEIVDGVCGDGDCHNTEGSFT----CHCRPGYKADD 195
D F Y D N TC++ EC +C G C GS C C+ G++
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECN--RAICRQG-CSPKHGSCKLPGDCRCQYGWQG-- 259
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
+ D+C + C G C N CE G +L KD++ C
Sbjct: 260 -----LYCDKCIPHPG-CVHGIC-NEPWQCLCETNWGGQLCD-----KDLNYCGTHQPCL 307
Query: 256 SNGACENQ-MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCRE 314
+ G C N YQC C EGY+ + + SC T + C C
Sbjct: 308 NGGTCSNTGPDKYQCSCPEGYSGPNCE---IAEHACLSDPCHNRGSCKETSLGFECECSP 364
Query: 315 GWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTC-------TDGLVPSAAGA 365
GW G +C +ID+C+ C GG C++ V + C C T L + A
Sbjct: 365 GW----TGPTCSTNIDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418
Query: 366 KPTCQDIDECADLISTIIMMSVDE-LQKSVDPQIPELCGA----GSCHNTIGSFVCQCPD 420
KP C + C +LI++ + + ++ D I + G SC + + + C CP
Sbjct: 419 KP-CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPP 477
Query: 421 GYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDE 478
GY+ G C D DEC + C C N FQC C G+ G+ C+ D+D
Sbjct: 478 GYA-----GDHCERDIDEC--ASNPCLNGGHCQNEINRFQCLCPTGFSGN--LCQLDIDY 528
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG-LRTVCCVYSCVDIDEC-----AND 532
C N C A C N + C C Y+G L+ C C ID C +ND
Sbjct: 529 CEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASND 586
Query: 533 P---------TLC-ENGHCSNTPGG-YECDCDVGFT 557
+C +G C + GG + CDC+ GFT
Sbjct: 587 TPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/161 (28%), Positives = 63/161 (39%), Gaps = 23/161 (14%)
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCD-CHPAADCINL-PGSFQCRCRDGWRGDGAT 472
+C P + G D D GT C C N P +QC C +G+ G
Sbjct: 275 ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY--SGPN 332
Query: 473 CEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
CE + CL++ CH R +C T F C C G+ G C +ID+C+
Sbjct: 333 CEIAEHACLSDP--CHNRGSCKETSLGFECECSPGWTG------PTC----STNIDDCS- 379
Query: 532 DPTLCEN-GHCSNTPGGYECDCD---VGFTRAADGRSCLGK 568
P C + G C + G++C C G T D C K
Sbjct: 380 -PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK 419
>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 155 bits (375), Expect = 5e-37
Identities = 139/498 (27%), Positives = 203/498 (40%), Gaps = 90/498 (18%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GD 173
Q++ NEC A P C + + C+NL+ + CDC PG+ + + +++N+C G C D
Sbjct: 410 QLDANECEAKP--CVNAKSCKNLIASYYCDCLPGWMGQNCD---ININDCL---GQCQND 461
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PGY D + DIDECA N L GG C N F+C C G
Sbjct: 462 ASCRDLVNGYRCICPPGYAGDHCER---DIDECASNPCL-NGGHCQNEINRFQCLCPTGF 517
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDE---GYAQSTVKSHXXXXXX 289
L DID C C NGA C N+ Y C C E G S +K H
Sbjct: 518 S---GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPC 572
Query: 290 XXXXXXRCQHSCVNTP----------------------GSYHCTCREGWHLRADGRSCRD 327
+ +TP G + C C +G+ G C +
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF----TGTYCHE 628
Query: 328 -IDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAG------AKPTCQDIDECADLI 379
I++C + PC GG C + V SY C C+DG + ++ C + C DL+
Sbjct: 629 NINDCE--SNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 380 STIIMMSVDELQ----KSVDPQIPEL-CG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
+ + + S D Q E C G+C++ +F C CP G+ +G C
Sbjct: 687 NDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW-----EGTTCN 741
Query: 434 DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCA 493
CH C+ SF C C++GW G ++ ++C + C+ TC
Sbjct: 742 IARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGP-ICAQNTNDCSPH--PCYNSGTCV 798
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDC 552
+ D +RC C G+ G C ++I+EC + P C G C + GY C C
Sbjct: 799 DGDNWYRCECAPGFAGPD------C----RININECQSSP--CAFGATCVDEINGYRCVC 846
Query: 553 DVGFTRA----ADGRSCL 566
G + A GR C+
Sbjct: 847 PPGHSGAKCQEVSGRPCI 864
Score = 137 bits (331), Expect = 1e-31
Identities = 126/458 (27%), Positives = 191/458 (41%), Gaps = 78/458 (17%)
Query: 119 VNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDC 176
+++C+ P C HG C++L+ GF C C P + TC +D NECE V C
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKS-C 427
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCRGGRCVNTAGSFRCECGHGM 233
N S+ C C PG+ + ++I++C NDA CR + +RC C G
Sbjct: 428 KNLIASYYCDCLPGWMGQNCD---ININDCLGQCQNDASCR-----DLVNGYRCICPPGY 479
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A D +DIDEC+ S C NG C+N++ +QC+C G++ + +
Sbjct: 480 --AGDHCE-RDIDECA--SNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ-----LDIDYC 529
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGW------HLRADGRS--CRDIDECAGGARPCGGGQ 342
CQ+ C N Y C C E + HL+ R+ C ID C +
Sbjct: 530 EPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPE 589
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
+ S C G S +G K TC D T ++++ + +
Sbjct: 590 GVRYISSNVCG-PHGKCKSQSGGKFTC---DCNKGFTGTYCHENINDCESN------PCR 639
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCR 461
G+C + + S+ C C DG+ +G C T+ ++C C H C +L F C
Sbjct: 640 NGGTCIDGVNSYKCICSDGW-----EGAYCETNINDCSQNPC--HNGGTCRDLVNDFYCD 692
Query: 462 CRDGWRGDGATCED--VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C++GW+G D DE NNGG TC + +F+C+C G++G T C
Sbjct: 693 CKNGWKGKTCHSRDSQCDEATCNNGG-----TCYDEGDAFKCMCPGGWEG------TTC- 740
Query: 520 VYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
+ C +P C N G C + C C G+
Sbjct: 741 --NIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGW 774
Score = 133 bits (321), Expect = 2e-30
Identities = 121/446 (27%), Positives = 181/446 (40%), Gaps = 57/446 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD 175
E+ E A C G C+ GF C+C PG+ TC ++++C + G
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGW----TGPTCSTNIDDCS-PNNCSHGGT 388
Query: 176 CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + F C C P + K C +D +EC + C N S+ C+C G
Sbjct: 389 CQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCV-NAKSCKNLIASYYCDCLPGWM 443
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C +I++C G C N A C + + Y+C+C GYA +
Sbjct: 444 ----GQNCDININDC---LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPC 496
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C N + C C G+ G C+ DID C PC G QC N Y
Sbjct: 497 LNG---GHCQNEINRFQCLCPTGF----SGNLCQLDIDYCE--PNPCQNGAQCYNRASDY 547
Query: 351 TCTCTDGLV-PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCH 408
C C + + + K C+ C + S + M+ ++ + V +CG G C
Sbjct: 548 FCKCPEDYEGKNCSHLKDHCR-TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCK 606
Query: 409 N-TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGW 466
+ + G F C C G++ G C ++ ++CE + C CI+ S++C C DGW
Sbjct: 607 SQSGGKFTCDCNKGFT-----GTYCHENINDCE--SNPCRNGGTCIDGVNSYKCICSDGW 659
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+GA CE ++++C N CH TC + F C C G+KG R C D
Sbjct: 660 --EGAYCETNINDCSQN--PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQC-----D 710
Query: 526 IDECANDPTLCENGHCSN--TPGGYE 549
C N T + G PGG+E
Sbjct: 711 EATCNNGGTCYDEGDAFKCMCPGGWE 736
Score = 109 bits (262), Expect = 3e-23
Identities = 125/456 (27%), Positives = 177/456 (38%), Gaps = 80/456 (17%)
Query: 144 DCFPGYEKDSK-NHTCVDV---NECEIVDGVCGDGDCHNTEGSFT----CHCRPGYKADD 195
D F Y D N TC++ EC +C G C GS C C+ G++
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECN--RAICRQG-CSPKHGSCKLPGDCRCQYGWQG-- 259
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
+ D+C + C G C N CE G +L KD++ C
Sbjct: 260 -----LYCDKCIPHPG-CVHGIC-NEPWQCLCETNWGGQLCD-----KDLNYCGTHQPCL 307
Query: 256 SNGACENQ-MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCRE 314
+ G C N YQC C EGY+ + + SC T + C C
Sbjct: 308 NGGTCSNTGPDKYQCSCPEGYSGPNCE---IAEHACLSDPCHNRGSCKETSLGFECECSP 364
Query: 315 GWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTC-------TDGLVPSAAGA 365
GW G +C +ID+C+ C GG C++ V + C C T L + A
Sbjct: 365 GW----TGPTCSTNIDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418
Query: 366 KPTCQDIDECADLISTIIMMSVDE-LQKSVDPQIPELCGA----GSCHNTIGSFVCQCPD 420
KP C + C +LI++ + + ++ D I + G SC + + + C CP
Sbjct: 419 KP-CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPP 477
Query: 421 GYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDE 478
GY+ G C D DEC + C C N FQC C G+ G+ C+ D+D
Sbjct: 478 GYA-----GDHCERDIDEC--ASNPCLNGGHCQNEINRFQCLCPTGFSGN--LCQLDIDY 528
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG-LRTVCCVYSCVDIDEC-----AND 532
C N C A C N + C C Y+G L+ C C ID C +ND
Sbjct: 529 CEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASND 586
Query: 533 P---------TLC-ENGHCSNTPGG-YECDCDVGFT 557
+C +G C + GG + CDC+ GFT
Sbjct: 587 TPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/161 (28%), Positives = 63/161 (39%), Gaps = 23/161 (14%)
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCD-CHPAADCINL-PGSFQCRCRDGWRGDGAT 472
+C P + G D D GT C C N P +QC C +G+ G
Sbjct: 275 ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY--SGPN 332
Query: 473 CEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
CE + CL++ CH R +C T F C C G+ G C +ID+C+
Sbjct: 333 CEIAEHACLSDP--CHNRGSCKETSLGFECECSPGWTG------PTC----STNIDDCS- 379
Query: 532 DPTLCEN-GHCSNTPGGYECDCD---VGFTRAADGRSCLGK 568
P C + G C + G++C C G T D C K
Sbjct: 380 -PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK 419
>AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 155 bits (375), Expect = 5e-37
Identities = 139/498 (27%), Positives = 203/498 (40%), Gaps = 90/498 (18%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GD 173
Q++ NEC A P C + + C+NL+ + CDC PG+ + + +++N+C G C D
Sbjct: 410 QLDANECEAKP--CVNAKSCKNLIASYYCDCLPGWMGQNCD---ININDCL---GQCQND 461
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PGY D + DIDECA N L GG C N F+C C G
Sbjct: 462 ASCRDLVNGYRCICPPGYAGDHCER---DIDECASNPCL-NGGHCQNEINRFQCLCPTGF 517
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDE---GYAQSTVKSHXXXXXX 289
L DID C C NGA C N+ Y C C E G S +K H
Sbjct: 518 S---GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPC 572
Query: 290 XXXXXXRCQHSCVNTP----------------------GSYHCTCREGWHLRADGRSCRD 327
+ +TP G + C C +G+ G C +
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF----TGTYCHE 628
Query: 328 -IDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAG------AKPTCQDIDECADLI 379
I++C + PC GG C + V SY C C+DG + ++ C + C DL+
Sbjct: 629 NINDCE--SNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 380 STIIMMSVDELQ----KSVDPQIPEL-CG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
+ + + S D Q E C G+C++ +F C CP G+ +G C
Sbjct: 687 NDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW-----EGTTCN 741
Query: 434 DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCA 493
CH C+ SF C C++GW G ++ ++C + C+ TC
Sbjct: 742 IARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGP-ICAQNTNDCSPH--PCYNSGTCV 798
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDC 552
+ D +RC C G+ G C ++I+EC + P C G C + GY C C
Sbjct: 799 DGDNWYRCECAPGFAGPD------C----RININECQSSP--CAFGATCVDEINGYRCVC 846
Query: 553 DVGFTRA----ADGRSCL 566
G + A GR C+
Sbjct: 847 PPGHSGAKCQEVSGRPCI 864
Score = 137 bits (331), Expect = 1e-31
Identities = 126/458 (27%), Positives = 191/458 (41%), Gaps = 78/458 (17%)
Query: 119 VNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDC 176
+++C+ P C HG C++L+ GF C C P + TC +D NECE V C
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKS-C 427
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCRGGRCVNTAGSFRCECGHGM 233
N S+ C C PG+ + ++I++C NDA CR + +RC C G
Sbjct: 428 KNLIASYYCDCLPGWMGQNCD---ININDCLGQCQNDASCR-----DLVNGYRCICPPGY 479
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A D +DIDEC+ S C NG C+N++ +QC+C G++ + +
Sbjct: 480 --AGDHCE-RDIDECA--SNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ-----LDIDYC 529
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGW------HLRADGRS--CRDIDECAGGARPCGGGQ 342
CQ+ C N Y C C E + HL+ R+ C ID C +
Sbjct: 530 EPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPE 589
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
+ S C G S +G K TC D T ++++ + +
Sbjct: 590 GVRYISSNVCG-PHGKCKSQSGGKFTC---DCNKGFTGTYCHENINDCESN------PCR 639
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCR 461
G+C + + S+ C C DG+ +G C T+ ++C C H C +L F C
Sbjct: 640 NGGTCIDGVNSYKCICSDGW-----EGAYCETNINDCSQNPC--HNGGTCRDLVNDFYCD 692
Query: 462 CRDGWRGDGATCED--VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C++GW+G D DE NNGG TC + +F+C+C G++G T C
Sbjct: 693 CKNGWKGKTCHSRDSQCDEATCNNGG-----TCYDEGDAFKCMCPGGWEG------TTC- 740
Query: 520 VYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
+ C +P C N G C + C C G+
Sbjct: 741 --NIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGW 774
Score = 133 bits (321), Expect = 2e-30
Identities = 121/446 (27%), Positives = 181/446 (40%), Gaps = 57/446 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD 175
E+ E A C G C+ GF C+C PG+ TC ++++C + G
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGW----TGPTCSTNIDDCS-PNNCSHGGT 388
Query: 176 CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + F C C P + K C +D +EC + C N S+ C+C G
Sbjct: 389 CQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCV-NAKSCKNLIASYYCDCLPGWM 443
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C +I++C G C N A C + + Y+C+C GYA +
Sbjct: 444 ----GQNCDININDC---LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPC 496
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C N + C C G+ G C+ DID C PC G QC N Y
Sbjct: 497 LNG---GHCQNEINRFQCLCPTGF----SGNLCQLDIDYCE--PNPCQNGAQCYNRASDY 547
Query: 351 TCTCTDGLV-PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCH 408
C C + + + K C+ C + S + M+ ++ + V +CG G C
Sbjct: 548 FCKCPEDYEGKNCSHLKDHCR-TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCK 606
Query: 409 N-TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGW 466
+ + G F C C G++ G C ++ ++CE + C CI+ S++C C DGW
Sbjct: 607 SQSGGKFTCDCNKGFT-----GTYCHENINDCE--SNPCRNGGTCIDGVNSYKCICSDGW 659
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+GA CE ++++C N CH TC + F C C G+KG R C D
Sbjct: 660 --EGAYCETNINDCSQN--PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQC-----D 710
Query: 526 IDECANDPTLCENGHCSN--TPGGYE 549
C N T + G PGG+E
Sbjct: 711 EATCNNGGTCYDEGDAFKCMCPGGWE 736
Score = 109 bits (262), Expect = 3e-23
Identities = 125/456 (27%), Positives = 177/456 (38%), Gaps = 80/456 (17%)
Query: 144 DCFPGYEKDSK-NHTCVDV---NECEIVDGVCGDGDCHNTEGSFT----CHCRPGYKADD 195
D F Y D N TC++ EC +C G C GS C C+ G++
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECN--RAICRQG-CSPKHGSCKLPGDCRCQYGWQG-- 259
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
+ D+C + C G C N CE G +L KD++ C
Sbjct: 260 -----LYCDKCIPHPG-CVHGIC-NEPWQCLCETNWGGQLCD-----KDLNYCGTHQPCL 307
Query: 256 SNGACENQ-MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCRE 314
+ G C N YQC C EGY+ + + SC T + C C
Sbjct: 308 NGGTCSNTGPDKYQCSCPEGYSGPNCE---IAEHACLSDPCHNRGSCKETSLGFECECSP 364
Query: 315 GWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTC-------TDGLVPSAAGA 365
GW G +C +ID+C+ C GG C++ V + C C T L + A
Sbjct: 365 GW----TGPTCSTNIDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418
Query: 366 KPTCQDIDECADLISTIIMMSVDE-LQKSVDPQIPELCGA----GSCHNTIGSFVCQCPD 420
KP C + C +LI++ + + ++ D I + G SC + + + C CP
Sbjct: 419 KP-CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPP 477
Query: 421 GYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDE 478
GY+ G C D DEC + C C N FQC C G+ G+ C+ D+D
Sbjct: 478 GYA-----GDHCERDIDEC--ASNPCLNGGHCQNEINRFQCLCPTGFSGN--LCQLDIDY 528
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG-LRTVCCVYSCVDIDEC-----AND 532
C N C A C N + C C Y+G L+ C C ID C +ND
Sbjct: 529 CEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASND 586
Query: 533 P---------TLC-ENGHCSNTPGG-YECDCDVGFT 557
+C +G C + GG + CDC+ GFT
Sbjct: 587 TPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/161 (28%), Positives = 63/161 (39%), Gaps = 23/161 (14%)
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCD-CHPAADCINL-PGSFQCRCRDGWRGDGAT 472
+C P + G D D GT C C N P +QC C +G+ G
Sbjct: 275 ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY--SGPN 332
Query: 473 CEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
CE + CL++ CH R +C T F C C G+ G C +ID+C+
Sbjct: 333 CEIAEHACLSDP--CHNRGSCKETSLGFECECSPGWTG------PTC----STNIDDCS- 379
Query: 532 DPTLCEN-GHCSNTPGGYECDCD---VGFTRAADGRSCLGK 568
P C + G C + G++C C G T D C K
Sbjct: 380 -PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK 419
>AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein
Jagged 1 protein.
Length = 1218
Score = 155 bits (375), Expect = 5e-37
Identities = 139/498 (27%), Positives = 203/498 (40%), Gaps = 90/498 (18%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GD 173
Q++ NEC A P C + + C+NL+ + CDC PG+ + + +++N+C G C D
Sbjct: 410 QLDANECEAKP--CVNAKSCKNLIASYYCDCLPGWMGQNCD---ININDCL---GQCQND 461
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PGY D + DIDECA N L GG C N F+C C G
Sbjct: 462 ASCRDLVNGYRCICPPGYAGDHCER---DIDECASNPCL-NGGHCQNEINRFQCLCPTGF 517
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDE---GYAQSTVKSHXXXXXX 289
L DID C C NGA C N+ Y C C E G S +K H
Sbjct: 518 S---GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPC 572
Query: 290 XXXXXXRCQHSCVNTP----------------------GSYHCTCREGWHLRADGRSCRD 327
+ +TP G + C C +G+ G C +
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF----TGTYCHE 628
Query: 328 -IDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAG------AKPTCQDIDECADLI 379
I++C + PC GG C + V SY C C+DG + ++ C + C DL+
Sbjct: 629 NINDCE--SNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 380 STIIMMSVDELQ----KSVDPQIPEL-CG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
+ + + S D Q E C G+C++ +F C CP G+ +G C
Sbjct: 687 NDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW-----EGTTCN 741
Query: 434 DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCA 493
CH C+ SF C C++GW G ++ ++C + C+ TC
Sbjct: 742 IARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGP-ICAQNTNDCSPH--PCYNSGTCV 798
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDC 552
+ D +RC C G+ G C ++I+EC + P C G C + GY C C
Sbjct: 799 DGDNWYRCECAPGFAGPD------C----RININECQSSP--CAFGATCVDEINGYRCVC 846
Query: 553 DVGFTRA----ADGRSCL 566
G + A GR C+
Sbjct: 847 PPGHSGAKCQEVSGRPCI 864
Score = 137 bits (331), Expect = 1e-31
Identities = 126/458 (27%), Positives = 191/458 (41%), Gaps = 78/458 (17%)
Query: 119 VNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDC 176
+++C+ P C HG C++L+ GF C C P + TC +D NECE V C
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKS-C 427
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCRGGRCVNTAGSFRCECGHGM 233
N S+ C C PG+ + ++I++C NDA CR + +RC C G
Sbjct: 428 KNLIASYYCDCLPGWMGQNCD---ININDCLGQCQNDASCR-----DLVNGYRCICPPGY 479
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A D +DIDEC+ S C NG C+N++ +QC+C G++ + +
Sbjct: 480 --AGDHCE-RDIDECA--SNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ-----LDIDYC 529
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGW------HLRADGRS--CRDIDECAGGARPCGGGQ 342
CQ+ C N Y C C E + HL+ R+ C ID C +
Sbjct: 530 EPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPE 589
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
+ S C G S +G K TC D T ++++ + +
Sbjct: 590 GVRYISSNVCG-PHGKCKSQSGGKFTC---DCNKGFTGTYCHENINDCESN------PCR 639
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCR 461
G+C + + S+ C C DG+ +G C T+ ++C C H C +L F C
Sbjct: 640 NGGTCIDGVNSYKCICSDGW-----EGAYCETNINDCSQNPC--HNGGTCRDLVNDFYCD 692
Query: 462 CRDGWRGDGATCED--VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C++GW+G D DE NNGG TC + +F+C+C G++G T C
Sbjct: 693 CKNGWKGKTCHSRDSQCDEATCNNGG-----TCYDEGDAFKCMCPGGWEG------TTC- 740
Query: 520 VYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
+ C +P C N G C + C C G+
Sbjct: 741 --NIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGW 774
Score = 133 bits (321), Expect = 2e-30
Identities = 121/446 (27%), Positives = 181/446 (40%), Gaps = 57/446 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD 175
E+ E A C G C+ GF C+C PG+ TC ++++C + G
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGW----TGPTCSTNIDDCS-PNNCSHGGT 388
Query: 176 CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + F C C P + K C +D +EC + C N S+ C+C G
Sbjct: 389 CQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCV-NAKSCKNLIASYYCDCLPGWM 443
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C +I++C G C N A C + + Y+C+C GYA +
Sbjct: 444 ----GQNCDININDC---LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPC 496
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C N + C C G+ G C+ DID C PC G QC N Y
Sbjct: 497 LNG---GHCQNEINRFQCLCPTGF----SGNLCQLDIDYCE--PNPCQNGAQCYNRASDY 547
Query: 351 TCTCTDGLV-PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCH 408
C C + + + K C+ C + S + M+ ++ + V +CG G C
Sbjct: 548 FCKCPEDYEGKNCSHLKDHCR-TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCK 606
Query: 409 N-TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGW 466
+ + G F C C G++ G C ++ ++CE + C CI+ S++C C DGW
Sbjct: 607 SQSGGKFTCDCNKGFT-----GTYCHENINDCE--SNPCRNGGTCIDGVNSYKCICSDGW 659
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+GA CE ++++C N CH TC + F C C G+KG R C D
Sbjct: 660 --EGAYCETNINDCSQN--PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQC-----D 710
Query: 526 IDECANDPTLCENGHCSN--TPGGYE 549
C N T + G PGG+E
Sbjct: 711 EATCNNGGTCYDEGDAFKCMCPGGWE 736
Score = 109 bits (262), Expect = 3e-23
Identities = 125/456 (27%), Positives = 177/456 (38%), Gaps = 80/456 (17%)
Query: 144 DCFPGYEKDSK-NHTCVDV---NECEIVDGVCGDGDCHNTEGSFT----CHCRPGYKADD 195
D F Y D N TC++ EC +C G C GS C C+ G++
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECN--RAICRQG-CSPKHGSCKLPGDCRCQYGWQG-- 259
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
+ D+C + C G C N CE G +L KD++ C
Sbjct: 260 -----LYCDKCIPHPG-CVHGIC-NEPWQCLCETNWGGQLCD-----KDLNYCGTHQPCL 307
Query: 256 SNGACENQ-MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCRE 314
+ G C N YQC C EGY+ + + SC T + C C
Sbjct: 308 NGGTCSNTGPDKYQCSCPEGYSGPNCE---IAEHACLSDPCHNRGSCKETSLGFECECSP 364
Query: 315 GWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTC-------TDGLVPSAAGA 365
GW G +C +ID+C+ C GG C++ V + C C T L + A
Sbjct: 365 GW----TGPTCSTNIDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418
Query: 366 KPTCQDIDECADLISTIIMMSVDE-LQKSVDPQIPELCGA----GSCHNTIGSFVCQCPD 420
KP C + C +LI++ + + ++ D I + G SC + + + C CP
Sbjct: 419 KP-CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPP 477
Query: 421 GYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDE 478
GY+ G C D DEC + C C N FQC C G+ G+ C+ D+D
Sbjct: 478 GYA-----GDHCERDIDEC--ASNPCLNGGHCQNEINRFQCLCPTGFSGN--LCQLDIDY 528
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG-LRTVCCVYSCVDIDEC-----AND 532
C N C A C N + C C Y+G L+ C C ID C +ND
Sbjct: 529 CEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASND 586
Query: 533 P---------TLC-ENGHCSNTPGG-YECDCDVGFT 557
+C +G C + GG + CDC+ GFT
Sbjct: 587 TPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/161 (28%), Positives = 63/161 (39%), Gaps = 23/161 (14%)
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCD-CHPAADCINL-PGSFQCRCRDGWRGDGAT 472
+C P + G D D GT C C N P +QC C +G+ G
Sbjct: 275 ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY--SGPN 332
Query: 473 CEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
CE + CL++ CH R +C T F C C G+ G C +ID+C+
Sbjct: 333 CEIAEHACLSDP--CHNRGSCKETSLGFECECSPGWTG------PTC----STNIDDCS- 379
Query: 532 DPTLCEN-GHCSNTPGGYECDCD---VGFTRAADGRSCLGK 568
P C + G C + G++C C G T D C K
Sbjct: 380 -PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK 419
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2005
Score = 154 bits (374), Expect = 7e-37
Identities = 142/462 (30%), Positives = 191/462 (41%), Gaps = 93/462 (20%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC PG C G C N LG F C C G E CE+ G C
Sbjct: 194 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGP----------RCELRAGPCPPR 243
Query: 175 DCHN---------TEGSF-TCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGS 224
C N + +F C C PG+ D V+ D C + GG C + +
Sbjct: 244 GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---VNPDNCVSHQCQ-NGGTCQDGLDT 299
Query: 225 FRCECGHGMELAPDRLSCKDIDECSITS-GICSN-GACENQMGTYQCVCDEGYAQSTVKS 282
+ C C E +D+DEC C N G C+N G++ CVC G+ ++ +
Sbjct: 300 YTCLC---PETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE 356
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGG 341
+ +C++ GS+ C C G G C D C ++PC G
Sbjct: 357 NLDDCIAATCAPG---STCIDRVGSFSCLCPPG----RTGLLCHLEDMCL--SQPCHGDA 407
Query: 342 QCRNT--VGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDELQKSVDPQI 398
QC GS C C G + PTC QD+DEC +M+ Q
Sbjct: 408 QCSTNPLTGSTLCLCQPGY------SGPTCHQDLDEC--------LMA---------QQG 444
Query: 399 PELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPG 456
P C GSC NT GSF C CP GY+ G C D +EC + CHP + C++L
Sbjct: 445 PSPCEHGGSCLNTPGSFNCLCPPGYT-----GSRCEADHNECL--SQPCHPGSTCLDLLA 497
Query: 457 SFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
+F C C G +G CE + +EC + C A C + F+C+C G+ G
Sbjct: 498 TFHCLCPPGL--EGQLCEVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSG------ 547
Query: 516 TVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
T C DIDEC + P C N G C + PG + C C GF
Sbjct: 548 TRC----EEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF 583
Score = 145 bits (351), Expect = 4e-34
Identities = 135/465 (29%), Positives = 192/465 (41%), Gaps = 70/465 (15%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGV-CGDGD-CHNTEGSFTCHCRP 189
G C++ L +TC C P E + DV+ECE C +G C N+ GSF C C
Sbjct: 291 GTCQDGLDTYTCLC-P--ETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVS 347
Query: 190 GYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC 248
G+ + ++D+C A C G C++ GSF C C G L C D C
Sbjct: 348 GWGGTSCEE---NLDDCIA--ATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC 398
Query: 249 SITSGICSNGACENQ--MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SCVNT 304
++ + C G+ C+C GY+ T C+H SC+NT
Sbjct: 399 -LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 457
Query: 305 PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTCTDGL---- 358
PGS++C C G+ G C D +EC ++PC G C + + ++ C C GL
Sbjct: 458 PGSFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPGLEGQL 511
Query: 359 --VPSAAGAKPTCQDIDECADLISTIIMM-----SVDELQKSVDPQIPELCG-AGSCHNT 410
V + A C + +C DL++ + S ++ +D C G C +
Sbjct: 512 CEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQ 571
Query: 411 IGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
G+F C+C G+ +GP C T+ DEC C A C++LPG+F C C G+ G
Sbjct: 572 PGAFHCKCLPGF-----EGPRCQTEVDECLSDPCPV--GASCLDLPGAFFCLCPSGFTGQ 624
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY------SC 523
CE V C N C P+ C + CLC G G C + SC
Sbjct: 625 --LCE-VPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 679
Query: 524 V-DI----DECANDPTLC------ENGHCSNTPGGYECDCDVGFT 557
V D+ EC + C G C P GY C C G+T
Sbjct: 680 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 724
Score = 139 bits (336), Expect = 3e-32
Identities = 128/464 (27%), Positives = 181/464 (39%), Gaps = 75/464 (16%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++E NECA+ P L H C +LL GF C C PG+ S D++EC G G
Sbjct: 513 EVETNECASAPCL-NHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRSSPCANG-GQ 567
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME- 234
C + G+F C C PG++ + ++DEC +D G C++ G+F C C G
Sbjct: 568 CQDQPGAFHCKCLPGFEG---PRCQTEVDECL-SDPCPVGASCLDLPGAFFCLCPSGFTG 623
Query: 235 -------LAPDRLSCKDI--DECSITSGICSNGACENQMGTYQCVCDEGYAQSTV----- 280
AP+ K I D+ + +C +G+ C C G+ Q +
Sbjct: 624 QLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDV 683
Query: 281 --KSHXXXXXXXXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGA 335
C H +C P Y+CTC G+ G +C ++ C G
Sbjct: 684 GWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSG- 738
Query: 336 RPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV 394
PC GG C + G Y CTC PS G P C Q S
Sbjct: 739 -PCLNGGSCNPSPGGYYCTCP----PSHTG--PQC---------------------QTST 770
Query: 395 DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCIN 453
D + C G+C N G+F C C G+ QGP C C A C +
Sbjct: 771 DYCVSAPCFNGGTCVNRPGTFSCLCAMGF-----QGPRCEGKLRPSCADSPCRNRATCQD 825
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
P +C C G+ G +C+ + + L C + C T SF CLC G+ G
Sbjct: 826 SPQGPRCLCPTGY--TGGSCQTLMD-LCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCN 882
Query: 514 LRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
L C + + + + +LC NG C ++ Y C C GF
Sbjct: 883 LPLSSCQKAA--LSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 924
Score = 136 bits (330), Expect = 1e-31
Identities = 128/457 (28%), Positives = 179/457 (39%), Gaps = 72/457 (15%)
Query: 130 GHGRCRN--LLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVD---GVCGDG-DCHNTEGS 182
G +C L G C C PGY TC D++EC + C G C NT GS
Sbjct: 405 GDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGS 460
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLS 241
F C C PGY S+ D +EC C G C++ +F C C G+E +L
Sbjct: 461 FNCLCPPGYTG---SRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE---GQLC 512
Query: 242 CKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+ +EC+ S C N A C + + +QC+C G++ + +
Sbjct: 513 EVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG---Q 567
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C + PG++HC C G+ +G C+ ++DEC P G C + G++ C C G
Sbjct: 568 CQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGAS-CLDLPGAFFCLCPSGFT 622
Query: 360 PSAAG----AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
A CQ C D + D P+ C G C +
Sbjct: 623 GQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---- 678
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD---CINLPGSFQCRCRDGWRGDGAT 472
C C G++ GP C E ELG C P A C P + C C G+ G T
Sbjct: 679 CVCDVGWT-----GPEC----EAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGP--T 727
Query: 473 C-EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
C E++ C ++G C +C + G + C C + G T CV + C N
Sbjct: 728 CSEEMTAC--HSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA-----PCFN 780
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
G C N PG + C C +GF G C GK
Sbjct: 781 ------GGTCVNRPGTFSCLCAMGF----QGPRCEGK 807
Score = 136 bits (329), Expect = 2e-31
Identities = 132/448 (29%), Positives = 176/448 (39%), Gaps = 78/448 (17%)
Query: 126 PGLCG-HGRCRNLLGGFT-CDCFPGY--EKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
P C GRC G C C PG+ E+ C N C V+G G C T
Sbjct: 126 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-SANPC--VNG----GVCLATYP 178
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRL 240
CHC PG++ + D++EC + C +G C NT GSF+C C G E L
Sbjct: 179 QIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCEL 235
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH- 299
++G E + C+C G+ + + +CQ+
Sbjct: 236 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSH-----QCQNG 290
Query: 300 -SCVNTPGSYHCTCREGWHLRADGRSC-RDIDEC-AGGARPC-GGGQCRNTVGSYTCTCT 355
+C + +Y C C E W G C D+DEC A G C GG C+N+ GS+ C C
Sbjct: 291 GTCQDGLDTYTCLCPETW----TGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCV 346
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSF 414
G G +++D+C I C GS C + +GSF
Sbjct: 347 SGW-----GGTSCEENLDDC----------------------IAATCAPGSTCIDRVGSF 379
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP--GSFQCRCRDGWRGDGAT 472
C CP G + G C +D C + CH A C P GS C C+ G+ G T
Sbjct: 380 SCLCPPGRT-----GLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLCQPGY--SGPT 430
Query: 473 C-EDVDECLTNNGG---CHPRATCANTDGSFRCLCDTGYKGDGYGL-RTVCCVYSCVDID 527
C +D+DECL G C +C NT GSF CLC GY G C C
Sbjct: 431 CHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 490
Query: 528 ECANDPTLCENGHCSNTPG--GYECDCD 553
C + L HC PG G C+ +
Sbjct: 491 TCLD---LLATFHCLCPPGLEGQLCEVE 515
Score = 118 bits (283), Expect = 7e-26
Identities = 127/459 (27%), Positives = 173/459 (37%), Gaps = 86/459 (18%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVC-G 172
+ E+ C + P C HG C G+ C C GY TC + + C G C
Sbjct: 691 EAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEMTACH--SGPCLN 742
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
G C+ + G + C C P + D C GG CVN G+F C C G
Sbjct: 743 GGSCNPSPGGYYCTCPPSHTGPQCQ---TSTDYCVSAPCF-NGGTCVNRPGTFSCLCAMG 798
Query: 233 MELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ P C+ S C N A C++ +C+C GY + ++
Sbjct: 799 FQ-GP---RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT--LMDLCAQ 852
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWH---LRADGRSCRD--IDECAGGARPC-GGGQCRN 345
R H C+ T S+HC C +GW SC+ + + + C GG C +
Sbjct: 853 KPCPRNSH-CLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVD 911
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
+ SY C C G S CQD V+P C G
Sbjct: 912 SGPSYFCHCPPGFQGS------LCQD---------------------HVNPCESRPCQNG 944
Query: 406 -SCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCR 463
+C ++CQC GY G C+ + D C+ + CH C PG F C C
Sbjct: 945 ATCMAQPSGYLCQCAPGY-----DGQNCSKELDACQ--SQPCHNHGTCTPKPGGFHCACP 997
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRAT--CANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ G CE DVDECL + CHP T C + +F C C G+ G
Sbjct: 998 PGF--VGLRCEGDVDECL--DQPCHPTGTAACHSLANAFYCQCLPGHTGQ---------- 1043
Query: 521 YSCVDIDECANDPTLCENGHCSNTPG---GYECDCDVGF 556
+ V+ID C + P G C T G G+ C C GF
Sbjct: 1044 WCEVEIDPCHSQPCF-HGGTCEATAGSPLGFICHCPKGF 1081
Score = 111 bits (268), Expect = 5e-24
Identities = 109/436 (25%), Positives = 164/436 (37%), Gaps = 70/436 (16%)
Query: 129 CGHGRCRNLLGGFTCDC-FPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
C HG C+ CD + G E +++ C+ C G C+ + C C
Sbjct: 669 CHHGHCQR--SSCVCDVGWTGPECEAELGGCISA-PC------AHGGTCYPQPSGYNCTC 719
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDE 247
GY S+ ++ C L GG C + G + C C P C+ +
Sbjct: 720 PTGYTGPTCSE---EMTACHSGPCL-NGGSCNPSPGGYYCTCPPS-HTGPQ---CQTSTD 771
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
+++ + G C N+ GT+ C+C G+ + R +C ++P
Sbjct: 772 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA--TCQDSPQG 829
Query: 308 YHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGA 365
C C G+ G SC+ + D CA +PC C T S+ C C G
Sbjct: 830 PRCLCPTGY----TGGSCQTLMDLCA--QKPCPRNSHCLQTGPSFHCLCLQGWTG----- 878
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSV 424
P C + + S + S + LC G C ++ S+ C CP G+
Sbjct: 879 -PLCN-----------LPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-- 924
Query: 425 KPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTN 482
QG C D + CE + C A C+ P + C+C G+ DG C +++D C +
Sbjct: 925 ---QGSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPGY--DGQNCSKELDACQSQ 977
Query: 483 NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT-LCENGHC 541
CH TC G F C C G+ GLR C D+DEC + P C
Sbjct: 978 P--CHNHGTCTPKPGGFHCACPPGF----VGLR---CE---GDVDECLDQPCHPTGTAAC 1025
Query: 542 SNTPGGYECDCDVGFT 557
+ + C C G T
Sbjct: 1026 HSLANAFYCQCLPGHT 1041
Score = 109 bits (263), Expect = 2e-23
Identities = 117/414 (28%), Positives = 161/414 (38%), Gaps = 67/414 (16%)
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNT--------------AGSF 225
G TC C PG+ + C D C N LC+ GG C SF
Sbjct: 49 GQGTCQCAPGF----LGETCQFPDPC-QNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSF 103
Query: 226 RCECGHGMELAPDRLSCKDIDECSITSGICSN-GACENQM-GTYQCVCDEGYAQSTVKSH 283
C C G +R + D C CS G C Q G QC C G+ +
Sbjct: 104 LCTCLPGF--TGERCQAQLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR 159
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGG- 341
C+ T C C G+ +G +C RD++EC PC G
Sbjct: 160 DFCSANPCVNGG----VCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGT 211
Query: 342 QCRNTVGSYTCTCTDGLV-PSA---AGAKP--------TCQDIDECADLISTIIM---MS 386
C NT+GS+ C C G P AG P TCQ + E +
Sbjct: 212 SCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI 271
Query: 387 VDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECEL-GTC 443
+ + + D + C G+C + + ++ C CP+ ++ G C++D DECE G
Sbjct: 272 GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT-----GWDCSEDVDECEAQGPP 326
Query: 444 DCHPAADCINLPGSFQCRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCL 502
C C N GSF C C GW G +CE+ +D+C+ C P +TC + GSF CL
Sbjct: 327 HCRNGGTCQNSAGSFHCVCVSGW--GGTSCEENLDDCIAAT--CAPGSTCIDRVGSFSCL 382
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPG--GYECDCDV 554
C G G L +C C +C+ +P L + C PG G C D+
Sbjct: 383 CPPGRTGLLCHLEDMCLSQPCHGDAQCSTNP-LTGSTLCLCQPGYSGPTCHQDL 435
Score = 73.3 bits (172), Expect = 2e-12
Identities = 115/474 (24%), Positives = 161/474 (33%), Gaps = 82/474 (17%)
Query: 131 HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN------TEGSFT 184
+ C F C C G+ N + + G+ CHN + S+
Sbjct: 858 NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF 917
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC-K 243
CHC PG++ +C D ++ G C+ + C+C G D +C K
Sbjct: 918 CHCPPGFQGS----LCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY----DGQNCSK 969
Query: 244 DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
++D C S C N G C + G + C C G+ + +C
Sbjct: 970 ELDACQ--SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTA-ACH 1026
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGS---YTCTCTDG 357
+ +++C C G H G+ C +ID C ++PC GG C T GS + C C G
Sbjct: 1027 SLANAFYCQCLPG-HT---GQWCEVEIDPCH--SQPCFHGGTCEATAGSPLGFICHCPKG 1080
Query: 358 LV-PSAAGAKPTCQDIDEC-----------ADLISTIIMMSVDELQKSVDPQIPELCGA- 404
P+ + P+C C +S + P P+ CG
Sbjct: 1081 FEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 1139
Query: 405 ------GSCHNTIG----SFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADCIN 453
GSC T G F C CP Q P + G CD + N
Sbjct: 1140 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1199
Query: 454 LPGSFQCRCR--DGWRGDGATCEDVDEC--LTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G C D W+G C C L +G CHP+ S CL D
Sbjct: 1200 WDGG-DCSLGVPDPWKG----CPSHSRCWLLFRDGQCHPQCD------SEECLFD----- 1243
Query: 510 DGYGLRTV-CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADG 562
GY T C + D+ +D NGHC EC D G R DG
Sbjct: 1244 -GYDCETPPACTPA---YDQYCHDHF--HNGHCEKGCNTAECGWDGGDCRPEDG 1291
Score = 70.5 bits (165), Expect = 1e-11
Identities = 64/231 (27%), Positives = 86/231 (37%), Gaps = 39/231 (16%)
Query: 331 CAGGARPCG-GGQCRN-TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
C PC GG C + ++G TC C G + CQ+ C + S ++
Sbjct: 30 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 89
Query: 389 -ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
L S P P SF+C C G++ G C E C
Sbjct: 90 LGLPSSPSPLTP-------------SFLCTCLPGFT-----GERCQAQLEDPCPPSFCSK 131
Query: 448 AADC-INLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
C I G QC C GW G+ C+ D C N C C T +C C G
Sbjct: 132 RGRCHIQASGRPQCSCMPGWTGE--QCQLRDFCSANP--CVNGGVCLATYPQIQCHCPPG 187
Query: 507 YKGDGYGLRTVCCVYSCV-DIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
++G ++C D++EC DP C G C NT G ++C C VG
Sbjct: 188 FEG-----------HACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 227
>AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.
Length = 1218
Score = 154 bits (373), Expect = 9e-37
Identities = 139/498 (27%), Positives = 203/498 (40%), Gaps = 90/498 (18%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GD 173
Q++ NEC A P C + + C+NL+ + CDC PG+ + + +++N+C G C D
Sbjct: 410 QLDANECEAKP--CVNAKSCKNLIASYYCDCLPGWMGQNCD---ININDCL---GQCQND 461
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C PGY D + DIDECA N L GG C N F+C C G
Sbjct: 462 ASCRDLVNGYRCICPPGYAGDHCER---DIDECASNPCL-DGGHCQNEINRFQCLCPTGF 517
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDE---GYAQSTVKSHXXXXXX 289
L DID C C NGA C N+ Y C C E G S +K H
Sbjct: 518 S---GNLCQLDIDYCEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPC 572
Query: 290 XXXXXXRCQHSCVNTP----------------------GSYHCTCREGWHLRADGRSCRD 327
+ +TP G + C C +G+ G C +
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF----TGTYCHE 628
Query: 328 -IDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAG------AKPTCQDIDECADLI 379
I++C + PC GG C + V SY C C+DG + ++ C + C DL+
Sbjct: 629 NINDCE--SNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 380 STIIMMSVDELQ----KSVDPQIPEL-CG-AGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
+ + + S D Q E C G+C++ +F C CP G+ +G C
Sbjct: 687 NDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW-----EGTTCN 741
Query: 434 DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCA 493
CH C+ SF C C++GW G ++ ++C + C+ TC
Sbjct: 742 IARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGP-ICAQNTNDCSPH--PCYNSGTCV 798
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDC 552
+ D +RC C G+ G C ++I+EC + P C G C + GY C C
Sbjct: 799 DGDNWYRCECAPGFAGPD------C----RININECQSSP--CAFGATCVDEINGYRCVC 846
Query: 553 DVGFTRA----ADGRSCL 566
G + A GR C+
Sbjct: 847 PPGHSGAKCQEVSGRPCI 864
Score = 135 bits (326), Expect = 5e-31
Identities = 125/458 (27%), Positives = 191/458 (41%), Gaps = 78/458 (17%)
Query: 119 VNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDC 176
+++C+ P C HG C++L+ GF C C P + TC +D NECE V C
Sbjct: 375 IDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCVNAKS-C 427
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCRGGRCVNTAGSFRCECGHGM 233
N S+ C C PG+ + ++I++C NDA CR + +RC C G
Sbjct: 428 KNLIASYYCDCLPGWMGQNCD---ININDCLGQCQNDASCR-----DLVNGYRCICPPGY 479
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A D +DIDEC+ S C +G C+N++ +QC+C G++ + +
Sbjct: 480 --AGDHCE-RDIDECA--SNPCLDGGHCQNEINRFQCLCPTGFSGNLCQ-----LDIDYC 529
Query: 293 XXXRCQHS--CVNTPGSYHCTCREGW------HLRADGRS--CRDIDECAGGARPCGGGQ 342
CQ+ C N Y C C E + HL+ R+ C ID C +
Sbjct: 530 EPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPE 589
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
+ S C G S +G K TC D T ++++ + +
Sbjct: 590 GVRYISSNVCG-PHGKCKSQSGGKFTC---DCNKGFTGTYCHENINDCESN------PCR 639
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCR 461
G+C + + S+ C C DG+ +G C T+ ++C C H C +L F C
Sbjct: 640 NGGTCIDGVNSYKCICSDGW-----EGAYCETNINDCSQNPC--HNGGTCRDLVNDFYCD 692
Query: 462 CRDGWRGDGATCED--VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C++GW+G D DE NNGG TC + +F+C+C G++G T C
Sbjct: 693 CKNGWKGKTCHSRDSQCDEATCNNGG-----TCYDEGDAFKCMCPGGWEG------TTC- 740
Query: 520 VYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
+ C +P C N G C + C C G+
Sbjct: 741 --NIARNSSCLPNP--CHNGGTCVVNGESFTCVCKEGW 774
Score = 133 bits (321), Expect = 2e-30
Identities = 121/446 (27%), Positives = 181/446 (40%), Gaps = 57/446 (12%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGD 175
E+ E A C G C+ GF C+C PG+ TC ++++C + G
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGW----TGPTCSTNIDDCS-PNNCSHGGT 388
Query: 176 CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C + F C C P + K C +D +EC + C N S+ C+C G
Sbjct: 389 CQDLVNGFKCVCPPQWT----GKTCQLDANECEAKPCV-NAKSCKNLIASYYCDCLPGWM 443
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
+C +I++C G C N A C + + Y+C+C GYA +
Sbjct: 444 ----GQNCDININDC---LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPC 496
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSY 350
C N + C C G+ G C+ DID C PC G QC N Y
Sbjct: 497 LDG---GHCQNEINRFQCLCPTGF----SGNLCQLDIDYCE--PNPCQNGAQCYNRASDY 547
Query: 351 TCTCTDGLV-PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCH 408
C C + + + K C+ C + S + M+ ++ + V +CG G C
Sbjct: 548 FCKCPEDYEGKNCSHLKDHCR-TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCK 606
Query: 409 N-TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGW 466
+ + G F C C G++ G C ++ ++CE + C CI+ S++C C DGW
Sbjct: 607 SQSGGKFTCDCNKGFT-----GTYCHENINDCE--SNPCRNGGTCIDGVNSYKCICSDGW 659
Query: 467 RGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+GA CE ++++C N CH TC + F C C G+KG R C D
Sbjct: 660 --EGAYCETNINDCSQN--PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQC-----D 710
Query: 526 IDECANDPTLCENGHCSN--TPGGYE 549
C N T + G PGG+E
Sbjct: 711 EATCNNGGTCYDEGDAFKCMCPGGWE 736
Score = 110 bits (265), Expect = 1e-23
Identities = 125/456 (27%), Positives = 177/456 (38%), Gaps = 80/456 (17%)
Query: 144 DCFPGYEKDSK-NHTCVDV---NECEIVDGVCGDGDCHNTEGSFT----CHCRPGYKADD 195
D F Y D N TC++ EC +C G C GS C C+ G++
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGRECN--RAICRQG-CSPKHGSCKLPGDCRCQYGWQG-- 259
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
+ D+C + C G C N CE G +L KD++ C
Sbjct: 260 -----LYCDKCIPHPG-CVHGIC-NEPWQCLCETNWGGQLCD-----KDLNYCGTHQPCL 307
Query: 256 SNGACENQ-MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCRE 314
+ G C N YQC C EGY+ + + SC T + C C
Sbjct: 308 NGGTCSNTGPDKYQCSCPEGYSGPNCE---IAEHACLSDPCHNRGSCKETSLGFECECSP 364
Query: 315 GWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTC-------TDGLVPSAAGA 365
GW G +C +ID+C+ C GG C++ V + C C T L + A
Sbjct: 365 GW----TGPTCSTNIDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418
Query: 366 KPTCQDIDECADLISTIIMMSVDE-LQKSVDPQIPELCGA----GSCHNTIGSFVCQCPD 420
KP C + C +LI++ + + ++ D I + G SC + + + C CP
Sbjct: 419 KP-CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPP 477
Query: 421 GYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDE 478
GY+ G C D DEC + C C N FQC C G+ G+ C+ D+D
Sbjct: 478 GYA-----GDHCERDIDEC--ASNPCLDGGHCQNEINRFQCLCPTGFSGN--LCQLDIDY 528
Query: 479 CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG-LRTVCCVYSCVDIDEC-----AND 532
C N C A C N + C C Y+G L+ C C ID C +ND
Sbjct: 529 CEPNP--CQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASND 586
Query: 533 P---------TLC-ENGHCSNTPGG-YECDCDVGFT 557
+C +G C + GG + CDC+ GFT
Sbjct: 587 TPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/161 (28%), Positives = 63/161 (39%), Gaps = 23/161 (14%)
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCD-CHPAADCINL-PGSFQCRCRDGWRGDGAT 472
+C P + G D D GT C C N P +QC C +G+ G
Sbjct: 275 ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY--SGPN 332
Query: 473 CEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
CE + CL++ CH R +C T F C C G+ G C +ID+C+
Sbjct: 333 CEIAEHACLSDP--CHNRGSCKETSLGFECECSPGWTG------PTC----STNIDDCS- 379
Query: 532 DPTLCEN-GHCSNTPGGYECDCD---VGFTRAADGRSCLGK 568
P C + G C + G++C C G T D C K
Sbjct: 380 -PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK 419
>AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein.
Length = 439
Score = 152 bits (369), Expect = 3e-36
Identities = 85/214 (39%), Positives = 106/214 (49%), Gaps = 11/214 (5%)
Query: 148 GYEKDSKNHTCVDVNECEIVDGVCGDG-DCHNTEGSFTCHCRPGYKADDFSKICVDIDEC 206
GYE D ++ +CVDV+EC C DCHN GS+ C C GY+ CVDIDEC
Sbjct: 108 GYEPDDQD-SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK--IGPECVDIDEC 164
Query: 207 ADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGT 266
C+ RCVN GSFRC+C G +L P+ SC D++EC + G C N GT
Sbjct: 165 RYR--YCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM--GAPCEQRCFNSYGT 219
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR 326
+ C C +GY CQ+ CVN PG + C C +G+ L A R C+
Sbjct: 220 FLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLAT-RLCQ 278
Query: 327 DIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
DIDEC GA Q C N G Y C T+ V
Sbjct: 279 DIDECESGAHQWSEAQTCVNFHGGYRCVDTNRCV 312
Score = 125 bits (301), Expect = 5e-28
Identities = 72/196 (36%), Positives = 94/196 (47%), Gaps = 10/196 (5%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C NL G + C C GY K CVD++EC C
Sbjct: 118 VDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE--CVDIDECRY--RYC-QHR 172
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GSF C C PG++ ++ CVD++EC D A C RC N+ G+F C C G EL
Sbjct: 173 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 230
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXX 294
D SC DIDECS +S +C C N+ G + C C +GY +T
Sbjct: 231 HRDGFSCSDIDECSYSSYLCQY-RCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQ 289
Query: 295 XRCQHSCVNTPGSYHC 310
+CVN G Y C
Sbjct: 290 WSEAQTCVNFHGGYRC 305
Score = 122 bits (295), Expect = 3e-27
Identities = 88/263 (33%), Positives = 120/263 (45%), Gaps = 37/263 (14%)
Query: 305 PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGLVPS-- 361
P SY C +G+ A+ CRD++EC C G +C N G Y C V +
Sbjct: 33 PDSY-TECTDGYTQTAN---CRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDL 88
Query: 362 -AAGAKP-----TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G P Q + + + VDE +++ P + CHN GS+
Sbjct: 89 HGEGPPPPVPPVNTQPLPTGYEPDDQDSCVDVDECAQALHDCRP----SQDCHNLPGSYQ 144
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATC 473
C CPDGY + GP C D DEC C H C+NLPGSF+C+C G++ + +C
Sbjct: 145 CTCPDGYR---KIGPECVDIDECRYRYCQ-H---RCVNLPGSFRCQCEPGFQLGPNNRSC 197
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDP 533
DV+EC C R C N+ G+F C C GY+ G +SC DIDEC+
Sbjct: 198 VDVNEC-DMGAPCEQR--CFNSYGTFLCRCHQGYELHRDG-------FSCSDIDECSYSS 247
Query: 534 TLCENGHCSNTPGGYECDCDVGF 556
LC+ C N PG + C C G+
Sbjct: 248 YLCQY-RCVNEPGRFSCHCPQGY 269
Score = 122 bits (293), Expect = 5e-27
Identities = 99/319 (31%), Positives = 128/319 (40%), Gaps = 53/319 (16%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVD 202
+C GY + + C DVNEC + C G+ C N G + C R +D
Sbjct: 38 ECTDGYTQTAN---CRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLH----- 89
Query: 203 IDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA-CE 261
+ VNT G E D+ SC D+DEC+ C C
Sbjct: 90 ------GEGPPPPVPPVNTQ-----PLPTGYE-PDDQDSCVDVDECAQALHDCRPSQDCH 137
Query: 262 NQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRAD 321
N G+YQC C +GY K CQH CVN PGS+ C C G+ L +
Sbjct: 138 NLPGSYQCTCPDGYR----KIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPN 193
Query: 322 GRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLIST 381
RSC D++EC GA PC +C N+ G++ C C G G +C DIDEC+
Sbjct: 194 NRSCVDVNECDMGA-PC-EQRCFNSYGTFLCRCHQGYELHRDGF--SCSDIDECS----- 244
Query: 382 IIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
LC C N G F C CP GY + + C D DECE G
Sbjct: 245 ---------------YSSYLC-QYRCVNEPGRFSCHCPQGYQLLATR--LCQDIDECESG 286
Query: 442 TCDCHPAADCINLPGSFQC 460
A C+N G ++C
Sbjct: 287 AHQWSEAQTCVNFHGGYRC 305
Score = 121 bits (291), Expect = 8e-27
Identities = 83/261 (31%), Positives = 117/261 (44%), Gaps = 31/261 (11%)
Query: 118 EVNECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+VNEC P C G +C N GG+ C P +++ + G+G
Sbjct: 51 DVNECLTIPEACKGEMKCINHYGGYLC--LP--------------RSAAVINDLHGEGPP 94
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGM-E 234
T GY+ DD CVD+DECA CR + C N GS++C C G +
Sbjct: 95 PPVPPVNTQPLPTGYEPDDQDS-CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 153
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
+ P+ C DIDEC C + C N G+++C C+ G+ Q +
Sbjct: 154 IGPE---CVDIDECRYR--YCQH-RCVNLPGSFRCQCEPGF-QLGPNNRSCVDVNECDMG 206
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
C+ C N+ G++ C C +G+ L DG SC DIDEC+ + C +C N G ++C C
Sbjct: 207 APCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLC-QYRCVNEPGRFSCHC 265
Query: 355 TDGLVPSAAGAKPTCQDIDEC 375
G A CQDIDEC
Sbjct: 266 PQGY---QLLATRLCQDIDEC 283
Score = 111 bits (268), Expect = 5e-24
Identities = 81/225 (36%), Positives = 106/225 (47%), Gaps = 30/225 (13%)
Query: 349 SYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII--MMSVDE------LQKSVDPQIPE 400
SYT CTDG +A C+D++EC + M ++ L +S I +
Sbjct: 35 SYT-ECTDGYTQTA-----NCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSA-AVIND 87
Query: 401 LCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC 460
L G G P GY +P+ +C D DEC DC P+ DC NLPGS+QC
Sbjct: 88 LHGEGPPPPVPPVNTQPLPTGY--EPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQC 145
Query: 461 RCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
C DG+R G C D+DEC C R C N GSFRC C+ G++ G R
Sbjct: 146 TCPDGYRKIGPECVDIDECRYRY--CQHR--CVNLPGSFRCQCEPGFQ-LGPNNR----- 195
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
SCVD++EC + CE C N+ G + C C G+ DG SC
Sbjct: 196 -SCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSC 237
Score = 107 bits (257), Expect = 1e-22
Identities = 81/234 (34%), Positives = 98/234 (41%), Gaps = 45/234 (19%)
Query: 321 DGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
D SC D+DECA C Q C N GSY CTC DG P C DI
Sbjct: 113 DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIG----PECVDI------- 161
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE 439
DE + C C N GSF CQC G+ + P +C D +EC+
Sbjct: 162 --------DECRY-------RYC-QHRCVNLPGSFRCQCEPGFQLGPNNR-SCVDVNECD 204
Query: 440 LGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDG 497
+G C C N G+F CRC G+ DG +C D+DEC ++ C R C N G
Sbjct: 205 MGA-PCEQR--CFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYR--CVNEPG 259
Query: 498 SFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDP-TLCENGHCSNTPGGYEC 550
F C C GY+ + C DIDEC + E C N GGY C
Sbjct: 260 RFSCHCPQGYQ--------LLATRLCQDIDECESGAHQWSEAQTCVNFHGGYRC 305
Score = 103 bits (247), Expect = 2e-21
Identities = 69/208 (33%), Positives = 93/208 (44%), Gaps = 33/208 (15%)
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
R C N PGSY CTC +G+ R G C DIDEC R C +C N GS+ C C
Sbjct: 131 RPSQDCHNLPGSYQCTCPDGY--RKIGPECVDIDECR--YRYCQH-RCVNLPGSFRCQCE 185
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G +C D++EC D P C C N+ G+F+
Sbjct: 186 PGF--QLGPNNRSCVDVNEC-------------------DMGAP--CEQ-RCFNSYGTFL 221
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGAT-CE 474
C+C GY + + G +C+D DEC + C C+N PG F C C G++ C+
Sbjct: 222 CRCHQGYELHRD-GFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQLLATRLCQ 278
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCL 502
D+DEC + TC N G +RC+
Sbjct: 279 DIDECESGAHQWSEAQTCVNFHGGYRCV 306
Score = 72.1 bits (169), Expect = 5e-12
Identities = 37/98 (37%), Positives = 47/98 (47%), Gaps = 12/98 (12%)
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
D +C DVDEC C P C N GS++C C GY+ G CVDIDE
Sbjct: 113 DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGP---------ECVDIDE 163
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C C++ C N PG + C C+ GF + RSC+
Sbjct: 164 CRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCV 198
>AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitamin
B12 receptor protein.
Length = 3494
Score = 151 bits (367), Expect = 5e-36
Identities = 113/332 (34%), Positives = 146/332 (43%), Gaps = 56/332 (16%)
Query: 245 IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SC 301
+D+ +S C NG C N ++ C+C + + CQ+ +C
Sbjct: 2 VDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC 61
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGA-RPCGGGQC----RNTVGS--YTCT 353
VNT GSY C C + G C D+C GG+ C G C R G Y+C
Sbjct: 62 VNTMGSYSCHCPPETY----GPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 117
Query: 354 CTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTI 411
C G + S P C D DEC+ Q P C C NT
Sbjct: 118 CDAGWMSSPNS--PACTLDRDECS-------------FQ-------PGPCSTLVQCFNTQ 155
Query: 412 GSFVC-QCPDGYSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCR-CRDGWR 467
GSF C CP G+ G C D +ECE+ G C P +C+N PGS C+ C G++
Sbjct: 156 GSFYCGACPTGWQ---GNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQ 212
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSF-RCLCDTGYKGDGYGLRTVCCVYSCVDI 526
GDG C D C +NGGCHP A+C++T GS C C GY G+GYG CV +
Sbjct: 213 GDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN------GCVQL 266
Query: 527 DE-CANDPTLCENGHCSNTPGGYECDCDVGFT 557
C + P C NG C +T GY C CD G+T
Sbjct: 267 SNICLSHP--CLNGQCIDTVSGYFCKCDSGWT 296
Score = 114 bits (275), Expect = 7e-25
Identities = 113/377 (29%), Positives = 153/377 (40%), Gaps = 68/377 (18%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGV---CGDGD-C 176
C++ P G G C NL F C C P + K C DVNECEI G C +G C
Sbjct: 7 CSSNPCQNG-GNCLNLHDSFFCICPPQW----KGPLCSADVNECEIYSGTPLSCQNGGTC 61
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD-IDECADND-ALCRGGRCVN----TAG--SFRCE 228
NT GS++CHC P + + C D+C A C G C + AG + C
Sbjct: 62 VNTMGSYSCHCPP----ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 117
Query: 229 CGHGMELAPDRLSCK-DIDECSITSGICSN-GACENQMGTYQC-VCDEGYAQS--TVKSH 283
C G +P+ +C D DECS G CS C N G++ C C G+ + +
Sbjct: 118 CDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDI 177
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHC-TCREGWHLRADGRSCRDIDECA---GGARPCG 339
CVNTPGS HC C G+ + DGR C D C+ GG P
Sbjct: 178 NECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRVCTLTDICSVSNGGCHP-- 233
Query: 340 GGQCRNTVGSY-TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQI 398
C +T+GS CTC G + G Q + C +
Sbjct: 234 DASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNIC----------------------L 271
Query: 399 PELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGS 457
C G C +T+ + C+C G++ G CT++ +EC + C C++ S
Sbjct: 272 SHPCLNGQCIDTVSGYFCKCDSGWT-----GVNCTENINECL--SNPCLNGGTCVDGVDS 324
Query: 458 FQCRCRDGWRGDGATCE 474
F C C W GA C+
Sbjct: 325 FSCECTRLW--TGALCQ 339
Score = 111 bits (267), Expect = 6e-24
Identities = 104/355 (29%), Positives = 139/355 (39%), Gaps = 54/355 (15%)
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCR-GGRCVNTAGSFRCEC 229
G+C N SF C C P +K S D++EC + C+ GG CVNT GS+ C C
Sbjct: 16 GNCLNLHDSFFCICPPQWKGPLCS---ADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHC 72
Query: 230 G---HGMELAPDRLSCKDIDECSITSGICSNGACENQMGT--YQCVCDEGYAQS-TVKSH 283
+G + A C+ GIC + Q G Y CVCD G+ S +
Sbjct: 73 PPETYGPQCASKYDDCEGGSVARCVHGICED-LMREQAGEPKYSCVCDAGWMSSPNSPAC 131
Query: 284 XXXXXXXXXXXXRCQH--SCVNTPGSYHC-TCREGWHLRADGRSCRDIDECA---GGARP 337
C C NT GS++C C GW + +G C DI+EC GG
Sbjct: 132 TLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGW--QGNGYICEDINECEINNGGCSV 189
Query: 338 CGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
+C NT GS C P G C D C+ +S P
Sbjct: 190 APPVECVNTPGSSHCQACP---PGYQGDGRVCTLTDICS--VSN----------GGCHPD 234
Query: 398 IPELCGAGSCHNTIGSF-VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD--CINL 454
SC +T+GS +C C GY+ C C HP + CI+
Sbjct: 235 -------ASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNI----CLSHPCLNGQCIDT 283
Query: 455 PGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
+ C+C GW G T E+++ECL+N C TC + SF C C + G
Sbjct: 284 VSGYFCKCDSGWTGVNCT-ENINECLSN--PCLNGGTCVDGVDSFSCECTRLWTG 335
Score = 81.0 bits (191), Expect = 1e-14
Identities = 62/211 (29%), Positives = 91/211 (43%), Gaps = 21/211 (9%)
Query: 117 MEVNECAAFPGLCGH-GRCRNLLGGFTCDCFP-GYEKDSKNHTCVDVNECEIVDGVCGDG 174
++ +EC+ PG C +C N G F C P G++ + C D+NECEI +G C
Sbjct: 133 LDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQ--GNGYICEDINECEINNGGCSVA 190
Query: 175 ---DCHNTEGSFTCH-CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSF-RCE 228
+C NT GS C C PGY+ D ++C D C+ ++ C C +T GS C
Sbjct: 191 PPVECVNTPGSSHCQACPPGYQGD--GRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCT 248
Query: 229 C--GH-GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXX 285
C G+ G P+ C + + S C NG C + + Y C CD G+ +
Sbjct: 249 CLPGYTGNGYGPN--GCVQLSNICL-SHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENIN 305
Query: 286 XXXXXXXXXXRCQHSCVNTPGSYHCTCREGW 316
+CV+ S+ C C W
Sbjct: 306 ECLSNPCLNG---GTCVDGVDSFSCECTRLW 333
Score = 52.8 bits (121), Expect = 3e-06
Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 15/128 (11%)
Query: 445 CHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNG---GCHPRATCANTDGSFRC 501
C +C+NL SF C C W+G + DV+EC +G C TC NT GS+ C
Sbjct: 12 CQNGGNCLNLHDSFFCICPPQWKGPLCSA-DVNECEIYSGTPLSCQNGGTCVNTMGSYSC 70
Query: 502 LCDTGYKGDGYGLRTVCCVYSCV--DIDECANDPTLCEN--GHCSNTPGGYECDCDVGFT 557
C + YG + C + C + +CE+ + P Y C CD G+
Sbjct: 71 HCPP----ETYGPQCASKYDDCEGGSVARCVHG--ICEDLMREQAGEPK-YSCVCDAGWM 123
Query: 558 RAADGRSC 565
+ + +C
Sbjct: 124 SSPNSPAC 131
>AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12
receptor precursor protein.
Length = 3623
Score = 151 bits (367), Expect = 5e-36
Identities = 113/332 (34%), Positives = 146/332 (43%), Gaps = 56/332 (16%)
Query: 245 IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SC 301
+D+ +S C NG C N ++ C+C + + CQ+ +C
Sbjct: 131 VDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC 190
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGA-RPCGGGQC----RNTVGS--YTCT 353
VNT GSY C C + G C D+C GG+ C G C R G Y+C
Sbjct: 191 VNTMGSYSCHCPPETY----GPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 354 CTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTI 411
C G + S P C D DEC+ Q P C C NT
Sbjct: 247 CDAGWMSSPNS--PACTLDRDECS-------------FQ-------PGPCSTLVQCFNTQ 284
Query: 412 GSFVC-QCPDGYSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCR-CRDGWR 467
GSF C CP G+ G C D +ECE+ G C P +C+N PGS C+ C G++
Sbjct: 285 GSFYCGACPTGWQ---GNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQ 341
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSF-RCLCDTGYKGDGYGLRTVCCVYSCVDI 526
GDG C D C +NGGCHP A+C++T GS C C GY G+GYG CV +
Sbjct: 342 GDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN------GCVQL 395
Query: 527 DE-CANDPTLCENGHCSNTPGGYECDCDVGFT 557
C + P C NG C +T GY C CD G+T
Sbjct: 396 SNICLSHP--CLNGQCIDTVSGYFCKCDSGWT 425
Score = 114 bits (275), Expect = 7e-25
Identities = 113/377 (29%), Positives = 153/377 (40%), Gaps = 68/377 (18%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGV---CGDGD-C 176
C++ P G G C NL F C C P + K C DVNECEI G C +G C
Sbjct: 136 CSSNPCQNG-GNCLNLHDSFFCICPPQW----KGPLCSADVNECEIYSGTPLSCQNGGTC 190
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD-IDECADND-ALCRGGRCVN----TAG--SFRCE 228
NT GS++CHC P + + C D+C A C G C + AG + C
Sbjct: 191 VNTMGSYSCHCPP----ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 229 CGHGMELAPDRLSCK-DIDECSITSGICSN-GACENQMGTYQC-VCDEGYAQS--TVKSH 283
C G +P+ +C D DECS G CS C N G++ C C G+ + +
Sbjct: 247 CDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDI 306
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHC-TCREGWHLRADGRSCRDIDECA---GGARPCG 339
CVNTPGS HC C G+ + DGR C D C+ GG P
Sbjct: 307 NECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRVCTLTDICSVSNGGCHP-- 362
Query: 340 GGQCRNTVGSY-TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQI 398
C +T+GS CTC G + G Q + C +
Sbjct: 363 DASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNIC----------------------L 400
Query: 399 PELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGS 457
C G C +T+ + C+C G++ G CT++ +EC + C C++ S
Sbjct: 401 SHPCLNGQCIDTVSGYFCKCDSGWT-----GVNCTENINECL--SNPCLNGGTCVDGVDS 453
Query: 458 FQCRCRDGWRGDGATCE 474
F C C W GA C+
Sbjct: 454 FSCECTRLW--TGALCQ 468
Score = 111 bits (267), Expect = 6e-24
Identities = 104/355 (29%), Positives = 139/355 (39%), Gaps = 54/355 (15%)
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCR-GGRCVNTAGSFRCEC 229
G+C N SF C C P +K S D++EC + C+ GG CVNT GS+ C C
Sbjct: 145 GNCLNLHDSFFCICPPQWKGPLCS---ADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHC 201
Query: 230 G---HGMELAPDRLSCKDIDECSITSGICSNGACENQMGT--YQCVCDEGYAQS-TVKSH 283
+G + A C+ GIC + Q G Y CVCD G+ S +
Sbjct: 202 PPETYGPQCASKYDDCEGGSVARCVHGICED-LMREQAGEPKYSCVCDAGWMSSPNSPAC 260
Query: 284 XXXXXXXXXXXXRCQH--SCVNTPGSYHC-TCREGWHLRADGRSCRDIDECA---GGARP 337
C C NT GS++C C GW + +G C DI+EC GG
Sbjct: 261 TLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGW--QGNGYICEDINECEINNGGCSV 318
Query: 338 CGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
+C NT GS C P G C D C+ +S P
Sbjct: 319 APPVECVNTPGSSHCQACP---PGYQGDGRVCTLTDICS--VSN----------GGCHPD 363
Query: 398 IPELCGAGSCHNTIGSF-VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD--CINL 454
SC +T+GS +C C GY+ C C HP + CI+
Sbjct: 364 -------ASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNI----CLSHPCLNGQCIDT 412
Query: 455 PGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
+ C+C GW G T E+++ECL+N C TC + SF C C + G
Sbjct: 413 VSGYFCKCDSGWTGVNCT-ENINECLSN--PCLNGGTCVDGVDSFSCECTRLWTG 464
Score = 81.0 bits (191), Expect = 1e-14
Identities = 62/211 (29%), Positives = 91/211 (43%), Gaps = 21/211 (9%)
Query: 117 MEVNECAAFPGLCGH-GRCRNLLGGFTCDCFP-GYEKDSKNHTCVDVNECEIVDGVCGDG 174
++ +EC+ PG C +C N G F C P G++ + C D+NECEI +G C
Sbjct: 262 LDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQ--GNGYICEDINECEINNGGCSVA 319
Query: 175 ---DCHNTEGSFTCH-CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSF-RCE 228
+C NT GS C C PGY+ D ++C D C+ ++ C C +T GS C
Sbjct: 320 PPVECVNTPGSSHCQACPPGYQGD--GRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCT 377
Query: 229 C--GH-GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXX 285
C G+ G P+ C + + S C NG C + + Y C CD G+ +
Sbjct: 378 CLPGYTGNGYGPN--GCVQLSNICL-SHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENIN 434
Query: 286 XXXXXXXXXXRCQHSCVNTPGSYHCTCREGW 316
+CV+ S+ C C W
Sbjct: 435 ECLSNPCLNG---GTCVDGVDSFSCECTRLW 462
Score = 52.8 bits (121), Expect = 3e-06
Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 15/128 (11%)
Query: 445 CHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNG---GCHPRATCANTDGSFRC 501
C +C+NL SF C C W+G + DV+EC +G C TC NT GS+ C
Sbjct: 141 CQNGGNCLNLHDSFFCICPPQWKGPLCSA-DVNECEIYSGTPLSCQNGGTCVNTMGSYSC 199
Query: 502 LCDTGYKGDGYGLRTVCCVYSCV--DIDECANDPTLCEN--GHCSNTPGGYECDCDVGFT 557
C + YG + C + C + +CE+ + P Y C CD G+
Sbjct: 200 HCPP----ETYGPQCASKYDDCEGGSVARCVHG--ICEDLMREQAGEPK-YSCVCDAGWM 252
Query: 558 RAADGRSC 565
+ + +C
Sbjct: 253 SSPNSPAC 260
Score = 44.4 bits (100), Expect = 0.001
Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 14/83 (16%)
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC---A 530
+ VD+ + ++ C C N SF C+C +KG +C D++EC +
Sbjct: 129 QTVDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKG------PLC----SADVNECEIYS 178
Query: 531 NDPTLCEN-GHCSNTPGGYECDC 552
P C+N G C NT G Y C C
Sbjct: 179 GTPLSCQNGGTCVNTMGSYSCHC 201
>AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 150 bits (364), Expect = 1e-35
Identities = 113/332 (34%), Positives = 146/332 (43%), Gaps = 56/332 (16%)
Query: 245 IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SC 301
+D+ +S C NG C N ++ C+C + + CQ+ +C
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC 190
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGA-RPCGGGQC----RNTVGS--YTCT 353
VNT GSY C C + G C D+C GG+ C G C R G Y+C
Sbjct: 191 VNTMGSYSCHCPPETY----GPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 354 CTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTI 411
C G + S P C D DEC+ Q P C C NT
Sbjct: 247 CDAGWMFSPNS--PACTLDRDECS-------------FQ-------PGPCSTLVQCFNTQ 284
Query: 412 GSFVC-QCPDGYSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCR-CRDGWR 467
GSF C CP G+ G C D +ECE+ G C P +C+N PGS C+ C G++
Sbjct: 285 GSFYCGACPTGWQ---GNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQ 341
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSF-RCLCDTGYKGDGYGLRTVCCVYSCVDI 526
GDG C D C +NGGCHP A+C++T GS C C GY G+GYG CV +
Sbjct: 342 GDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN------GCVQL 395
Query: 527 DE-CANDPTLCENGHCSNTPGGYECDCDVGFT 557
C + P C NG C +T GY C CD G+T
Sbjct: 396 SNICLSHP--CLNGQCIDTVSGYFCKCDSGWT 425
Score = 124 bits (299), Expect = 8e-28
Identities = 114/368 (30%), Positives = 149/368 (40%), Gaps = 56/368 (15%)
Query: 201 VDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGI---CSN 257
VD C+ N GG C+N SF C C + P L D++EC I SG C N
Sbjct: 131 VDKKVCSSNPCQ-NGGTCLNLHDSFFCICPPQWK-GP--LCSADVNECEIYSGTPLSCQN 186
Query: 258 -GACENQMGTYQCVC-DEGYAQSTVKSHXXXXXXXXXXXXR--CQHSCVNTPG--SYHCT 311
G C N MG+Y C C E Y + C+ G Y C
Sbjct: 187 GGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 312 CREGWHLRADGRSCR-DIDECAGGARPCGG-GQCRNTVGSYTCTCTDGLVPSA-AGAKPT 368
C GW + +C D DEC+ PC QC NT GS+ C G P+ G
Sbjct: 247 CDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYC----GACPTGWQGNGYI 302
Query: 369 CQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQ-CPDGYSVKPE 427
C+DI+EC ++ SV P + C NT GS CQ CP GY
Sbjct: 303 CEDINEC----------EINNGGCSVAPPV-------ECVNTPGSSHCQACPPGYQ---G 342
Query: 428 QGPACTDDDECELGTCDCHPAADCINLPGSFQ-CRCRDGWRGDGATCEDVDECLTNNGGC 486
G CT D C + CHP A C + GS C C G+ G+G + L+N
Sbjct: 343 DGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQ-LSNICLS 401
Query: 487 HP--RATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNT 544
HP C +T + C CD+G+ G V C +I+EC ++P L G C +
Sbjct: 402 HPCLNGQCIDTVSGYFCKCDSGWTG-------VNCT---ENINECLSNPCL-NGGTCVDG 450
Query: 545 PGGYECDC 552
+ C+C
Sbjct: 451 VDSFSCEC 458
Score = 115 bits (276), Expect = 5e-25
Identities = 113/377 (29%), Positives = 152/377 (40%), Gaps = 68/377 (18%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGV---C-GDGDC 176
C++ P G G C NL F C C P + K C DVNECEI G C G C
Sbjct: 136 CSSNPCQNG-GTCLNLHDSFFCICPPQW----KGPLCSADVNECEIYSGTPLSCQNGGTC 190
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD-IDECADND-ALCRGGRCVN----TAG--SFRCE 228
NT GS++CHC P + + C D+C A C G C + AG + C
Sbjct: 191 VNTMGSYSCHCPP----ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 229 CGHGMELAPDRLSCK-DIDECSITSGICSN-GACENQMGTYQC-VCDEGYAQS--TVKSH 283
C G +P+ +C D DECS G CS C N G++ C C G+ + +
Sbjct: 247 CDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDI 306
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHC-TCREGWHLRADGRSCRDIDECA---GGARPCG 339
CVNTPGS HC C G+ + DGR C D C+ GG P
Sbjct: 307 NECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRVCTLTDICSVSNGGCHP-- 362
Query: 340 GGQCRNTVGSY-TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQI 398
C +T+GS CTC G + G Q + C +
Sbjct: 363 DASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNIC----------------------L 400
Query: 399 PELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGS 457
C G C +T+ + C+C G++ G CT++ +EC + C C++ S
Sbjct: 401 SHPCLNGQCIDTVSGYFCKCDSGWT-----GVNCTENINECL--SNPCLNGGTCVDGVDS 453
Query: 458 FQCRCRDGWRGDGATCE 474
F C C W GA C+
Sbjct: 454 FSCECTRLW--TGALCQ 468
Score = 109 bits (262), Expect = 3e-23
Identities = 105/355 (29%), Positives = 136/355 (38%), Gaps = 54/355 (15%)
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCR-GGRCVNTAGSFRCEC 229
G C N SF C C P +K S D++EC + C+ GG CVNT GS+ C C
Sbjct: 145 GTCLNLHDSFFCICPPQWKGPLCS---ADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHC 201
Query: 230 ---GHGMELAPDRLSCKDIDECSITSGICSNGACENQMG--TYQCVCDEGYAQS-TVKSH 283
+G + A C+ GIC + Q G Y CVCD G+ S +
Sbjct: 202 PPETYGPQCASKYDDCEGGSVARCVHGICED-LMREQAGEPKYSCVCDAGWMFSPNSPAC 260
Query: 284 XXXXXXXXXXXXRCQH--SCVNTPGSYHC-TCREGWHLRADGRSCRDIDECA---GGARP 337
C C NT GS++C C GW + +G C DI+EC GG
Sbjct: 261 TLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGW--QGNGYICEDINECEINNGGCSV 318
Query: 338 CGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
+C NT GS C P G C D C SV D
Sbjct: 319 APPVECVNTPGSSHC---QACPPGYQGDGRVCTLTDIC----------SVSNGGCHPD-- 363
Query: 398 IPELCGAGSCHNTIGSF-VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPA--ADCINL 454
SC +T+GS +C C GY+ C C HP CI+
Sbjct: 364 -------ASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLS----NICLSHPCLNGQCIDT 412
Query: 455 PGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
+ C+C GW G T E+++ECL+N C TC + SF C C + G
Sbjct: 413 VSGYFCKCDSGWTGVNCT-ENINECLSN--PCLNGGTCVDGVDSFSCECTRLWTG 464
Score = 97.5 bits (232), Expect = 1e-19
Identities = 79/257 (30%), Positives = 105/257 (40%), Gaps = 20/257 (7%)
Query: 118 EVNECAAFPGL---CGHG-RCRNLLGGFTCDCFP---GYEKDSKNHTCVDVNECEIVDGV 170
+VNEC + G C +G C N +G ++C C P G + SK C + V G+
Sbjct: 170 DVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI 229
Query: 171 CGDGDCHNT-EGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRG-GRCVNTAGSFRC 227
C D E ++C C G+ S C +D DEC+ C +C NT GSF C
Sbjct: 230 CEDLMREQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYC 289
Query: 228 -ECGHGMELAPDRLSCKDIDECSITSGICSNGA---CENQMGTYQC-VCDEGYAQSTVKS 282
C G + + C+DI+EC I +G CS C N G+ C C GY
Sbjct: 290 GACPTGWQ--GNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVC 347
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGSYH-CTCREGWHLRADG-RSCRDIDECAGGARPCGG 340
SC +T GS CTC G+ G C + + PC
Sbjct: 348 TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICL-SHPCLN 406
Query: 341 GQCRNTVGSYTCTCTDG 357
GQC +TV Y C C G
Sbjct: 407 GQCIDTVSGYFCKCDSG 423
Score = 84.6 bits (200), Expect = 8e-16
Identities = 82/257 (31%), Positives = 101/257 (39%), Gaps = 59/257 (22%)
Query: 328 IDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMM 385
+D+ + PC GG C N S+ C C P G P C D++EC T
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICP----PQWKG--PLCSADVNECEIYSGT---- 180
Query: 386 SVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPE-QGPACTDD-DECELGT 442
P C G+C NT+GS+ C CP PE GP C D+CE G+
Sbjct: 181 -------------PLSCQNGGTCVNTMGSYSCHCP------PETYGPQCASKYDDCEGGS 221
Query: 443 CDCHPAADCINL------PGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCA 493
C +L + C C GW A D DEC G C C
Sbjct: 222 VARCVHGICEDLMREQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCF 281
Query: 494 NTDGSFRC-LCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG---HCSNTPGGYE 549
NT GSF C C TG++G+G Y C DI+EC + C C NTPG
Sbjct: 282 NTQGSFYCGACPTGWQGNG---------YICEDINECEINNGGCSVAPPVECVNTPGSSH 332
Query: 550 CD-CDVGFTRAADGRSC 565
C C G+ DGR C
Sbjct: 333 CQACPPGY--QGDGRVC 347
Score = 81.0 bits (191), Expect = 1e-14
Identities = 62/211 (29%), Positives = 91/211 (43%), Gaps = 21/211 (9%)
Query: 117 MEVNECAAFPGLCGH-GRCRNLLGGFTCDCFP-GYEKDSKNHTCVDVNECEIVDGVCGDG 174
++ +EC+ PG C +C N G F C P G++ + C D+NECEI +G C
Sbjct: 262 LDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQ--GNGYICEDINECEINNGGCSVA 319
Query: 175 ---DCHNTEGSFTCH-CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR-CE 228
+C NT GS C C PGY+ D ++C D C+ ++ C C +T GS C
Sbjct: 320 PPVECVNTPGSSHCQACPPGYQGD--GRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCT 377
Query: 229 C--GH-GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXX 285
C G+ G P+ C + + S C NG C + + Y C CD G+ +
Sbjct: 378 CLPGYTGNGYGPN--GCVQLSNICL-SHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENIN 434
Query: 286 XXXXXXXXXXRCQHSCVNTPGSYHCTCREGW 316
+CV+ S+ C C W
Sbjct: 435 ECLSNPCLNG---GTCVDGVDSFSCECTRLW 462
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 14/83 (16%)
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC---A 530
+ VD+ + ++ C TC N SF C+C +KG +C D++EC +
Sbjct: 129 QTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKG------PLC----SADVNECEIYS 178
Query: 531 NDPTLCEN-GHCSNTPGGYECDC 552
P C+N G C NT G Y C C
Sbjct: 179 GTPLSCQNGGTCVNTMGSYSCHC 201
>AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 150 bits (364), Expect = 1e-35
Identities = 113/332 (34%), Positives = 146/332 (43%), Gaps = 56/332 (16%)
Query: 245 IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SC 301
+D+ +S C NG C N ++ C+C + + CQ+ +C
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC 190
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGA-RPCGGGQC----RNTVGS--YTCT 353
VNT GSY C C + G C D+C GG+ C G C R G Y+C
Sbjct: 191 VNTMGSYSCHCPPETY----GPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 354 CTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTI 411
C G + S P C D DEC+ Q P C C NT
Sbjct: 247 CDAGWMFSPNS--PACTLDRDECS-------------FQ-------PGPCSTLVQCFNTQ 284
Query: 412 GSFVC-QCPDGYSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCR-CRDGWR 467
GSF C CP G+ G C D +ECE+ G C P +C+N PGS C+ C G++
Sbjct: 285 GSFYCGACPTGWQ---GNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQ 341
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSF-RCLCDTGYKGDGYGLRTVCCVYSCVDI 526
GDG C D C +NGGCHP A+C++T GS C C GY G+GYG CV +
Sbjct: 342 GDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN------GCVQL 395
Query: 527 DE-CANDPTLCENGHCSNTPGGYECDCDVGFT 557
C + P C NG C +T GY C CD G+T
Sbjct: 396 SNICLSHP--CLNGQCIDTVSGYFCKCDSGWT 425
Score = 124 bits (299), Expect = 8e-28
Identities = 114/368 (30%), Positives = 149/368 (40%), Gaps = 56/368 (15%)
Query: 201 VDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGI---CSN 257
VD C+ N GG C+N SF C C + P L D++EC I SG C N
Sbjct: 131 VDKKVCSSNPCQ-NGGTCLNLHDSFFCICPPQWK-GP--LCSADVNECEIYSGTPLSCQN 186
Query: 258 -GACENQMGTYQCVC-DEGYAQSTVKSHXXXXXXXXXXXXR--CQHSCVNTPG--SYHCT 311
G C N MG+Y C C E Y + C+ G Y C
Sbjct: 187 GGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 312 CREGWHLRADGRSCR-DIDECAGGARPCGG-GQCRNTVGSYTCTCTDGLVPSA-AGAKPT 368
C GW + +C D DEC+ PC QC NT GS+ C G P+ G
Sbjct: 247 CDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYC----GACPTGWQGNGYI 302
Query: 369 CQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQ-CPDGYSVKPE 427
C+DI+EC ++ SV P + C NT GS CQ CP GY
Sbjct: 303 CEDINEC----------EINNGGCSVAPPV-------ECVNTPGSSHCQACPPGYQ---G 342
Query: 428 QGPACTDDDECELGTCDCHPAADCINLPGSFQ-CRCRDGWRGDGATCEDVDECLTNNGGC 486
G CT D C + CHP A C + GS C C G+ G+G + L+N
Sbjct: 343 DGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQ-LSNICLS 401
Query: 487 HP--RATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNT 544
HP C +T + C CD+G+ G V C +I+EC ++P L G C +
Sbjct: 402 HPCLNGQCIDTVSGYFCKCDSGWTG-------VNCT---ENINECLSNPCL-NGGTCVDG 450
Query: 545 PGGYECDC 552
+ C+C
Sbjct: 451 VDSFSCEC 458
Score = 115 bits (276), Expect = 5e-25
Identities = 113/377 (29%), Positives = 152/377 (40%), Gaps = 68/377 (18%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGV---C-GDGDC 176
C++ P G G C NL F C C P + K C DVNECEI G C G C
Sbjct: 136 CSSNPCQNG-GTCLNLHDSFFCICPPQW----KGPLCSADVNECEIYSGTPLSCQNGGTC 190
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD-IDECADND-ALCRGGRCVN----TAG--SFRCE 228
NT GS++CHC P + + C D+C A C G C + AG + C
Sbjct: 191 VNTMGSYSCHCPP----ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 229 CGHGMELAPDRLSCK-DIDECSITSGICSN-GACENQMGTYQC-VCDEGYAQS--TVKSH 283
C G +P+ +C D DECS G CS C N G++ C C G+ + +
Sbjct: 247 CDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDI 306
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHC-TCREGWHLRADGRSCRDIDECA---GGARPCG 339
CVNTPGS HC C G+ + DGR C D C+ GG P
Sbjct: 307 NECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRVCTLTDICSVSNGGCHP-- 362
Query: 340 GGQCRNTVGSY-TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQI 398
C +T+GS CTC G + G Q + C +
Sbjct: 363 DASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNIC----------------------L 400
Query: 399 PELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGS 457
C G C +T+ + C+C G++ G CT++ +EC + C C++ S
Sbjct: 401 SHPCLNGQCIDTVSGYFCKCDSGWT-----GVNCTENINECL--SNPCLNGGTCVDGVDS 453
Query: 458 FQCRCRDGWRGDGATCE 474
F C C W GA C+
Sbjct: 454 FSCECTRLW--TGALCQ 468
Score = 109 bits (262), Expect = 3e-23
Identities = 105/355 (29%), Positives = 136/355 (38%), Gaps = 54/355 (15%)
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCR-GGRCVNTAGSFRCEC 229
G C N SF C C P +K S D++EC + C+ GG CVNT GS+ C C
Sbjct: 145 GTCLNLHDSFFCICPPQWKGPLCS---ADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHC 201
Query: 230 ---GHGMELAPDRLSCKDIDECSITSGICSNGACENQMG--TYQCVCDEGYAQS-TVKSH 283
+G + A C+ GIC + Q G Y CVCD G+ S +
Sbjct: 202 PPETYGPQCASKYDDCEGGSVARCVHGICED-LMREQAGEPKYSCVCDAGWMFSPNSPAC 260
Query: 284 XXXXXXXXXXXXRCQH--SCVNTPGSYHC-TCREGWHLRADGRSCRDIDECA---GGARP 337
C C NT GS++C C GW + +G C DI+EC GG
Sbjct: 261 TLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGW--QGNGYICEDINECEINNGGCSV 318
Query: 338 CGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
+C NT GS C P G C D C SV D
Sbjct: 319 APPVECVNTPGSSHC---QACPPGYQGDGRVCTLTDIC----------SVSNGGCHPD-- 363
Query: 398 IPELCGAGSCHNTIGSF-VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPA--ADCINL 454
SC +T+GS +C C GY+ C C HP CI+
Sbjct: 364 -------ASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLS----NICLSHPCLNGQCIDT 412
Query: 455 PGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
+ C+C GW G T E+++ECL+N C TC + SF C C + G
Sbjct: 413 VSGYFCKCDSGWTGVNCT-ENINECLSN--PCLNGGTCVDGVDSFSCECTRLWTG 464
Score = 97.5 bits (232), Expect = 1e-19
Identities = 79/257 (30%), Positives = 105/257 (40%), Gaps = 20/257 (7%)
Query: 118 EVNECAAFPGL---CGHG-RCRNLLGGFTCDCFP---GYEKDSKNHTCVDVNECEIVDGV 170
+VNEC + G C +G C N +G ++C C P G + SK C + V G+
Sbjct: 170 DVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI 229
Query: 171 CGDGDCHNT-EGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRG-GRCVNTAGSFRC 227
C D E ++C C G+ S C +D DEC+ C +C NT GSF C
Sbjct: 230 CEDLMREQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYC 289
Query: 228 -ECGHGMELAPDRLSCKDIDECSITSGICSNGA---CENQMGTYQC-VCDEGYAQSTVKS 282
C G + + C+DI+EC I +G CS C N G+ C C GY
Sbjct: 290 GACPTGWQ--GNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVC 347
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGSYH-CTCREGWHLRADG-RSCRDIDECAGGARPCGG 340
SC +T GS CTC G+ G C + + PC
Sbjct: 348 TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICL-SHPCLN 406
Query: 341 GQCRNTVGSYTCTCTDG 357
GQC +TV Y C C G
Sbjct: 407 GQCIDTVSGYFCKCDSG 423
Score = 84.6 bits (200), Expect = 8e-16
Identities = 82/257 (31%), Positives = 101/257 (39%), Gaps = 59/257 (22%)
Query: 328 IDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMM 385
+D+ + PC GG C N S+ C C P G P C D++EC T
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICP----PQWKG--PLCSADVNECEIYSGT---- 180
Query: 386 SVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPE-QGPACTDD-DECELGT 442
P C G+C NT+GS+ C CP PE GP C D+CE G+
Sbjct: 181 -------------PLSCQNGGTCVNTMGSYSCHCP------PETYGPQCASKYDDCEGGS 221
Query: 443 CDCHPAADCINL------PGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCA 493
C +L + C C GW A D DEC G C C
Sbjct: 222 VARCVHGICEDLMREQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCF 281
Query: 494 NTDGSFRC-LCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG---HCSNTPGGYE 549
NT GSF C C TG++G+G Y C DI+EC + C C NTPG
Sbjct: 282 NTQGSFYCGACPTGWQGNG---------YICEDINECEINNGGCSVAPPVECVNTPGSSH 332
Query: 550 CD-CDVGFTRAADGRSC 565
C C G+ DGR C
Sbjct: 333 CQACPPGY--QGDGRVC 347
Score = 81.0 bits (191), Expect = 1e-14
Identities = 62/211 (29%), Positives = 91/211 (43%), Gaps = 21/211 (9%)
Query: 117 MEVNECAAFPGLCGH-GRCRNLLGGFTCDCFP-GYEKDSKNHTCVDVNECEIVDGVCGDG 174
++ +EC+ PG C +C N G F C P G++ + C D+NECEI +G C
Sbjct: 262 LDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQ--GNGYICEDINECEINNGGCSVA 319
Query: 175 ---DCHNTEGSFTCH-CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR-CE 228
+C NT GS C C PGY+ D ++C D C+ ++ C C +T GS C
Sbjct: 320 PPVECVNTPGSSHCQACPPGYQGD--GRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCT 377
Query: 229 C--GH-GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXX 285
C G+ G P+ C + + S C NG C + + Y C CD G+ +
Sbjct: 378 CLPGYTGNGYGPN--GCVQLSNICL-SHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENIN 434
Query: 286 XXXXXXXXXXRCQHSCVNTPGSYHCTCREGW 316
+CV+ S+ C C W
Sbjct: 435 ECLSNPCLNG---GTCVDGVDSFSCECTRLW 462
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 14/83 (16%)
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC---A 530
+ VD+ + ++ C TC N SF C+C +KG +C D++EC +
Sbjct: 129 QTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKG------PLC----SADVNECEIYS 178
Query: 531 NDPTLCEN-GHCSNTPGGYECDC 552
P C+N G C NT G Y C C
Sbjct: 179 GTPLSCQNGGTCVNTMGSYSCHC 201
>AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 150 bits (364), Expect = 1e-35
Identities = 113/332 (34%), Positives = 146/332 (43%), Gaps = 56/332 (16%)
Query: 245 IDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SC 301
+D+ +S C NG C N ++ C+C + + CQ+ +C
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC 190
Query: 302 VNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGA-RPCGGGQC----RNTVGS--YTCT 353
VNT GSY C C + G C D+C GG+ C G C R G Y+C
Sbjct: 191 VNTMGSYSCHCPPETY----GPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 354 CTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTI 411
C G + S P C D DEC+ Q P C C NT
Sbjct: 247 CDAGWMFSPNS--PACTLDRDECS-------------FQ-------PGPCSTLVQCFNTQ 284
Query: 412 GSFVC-QCPDGYSVKPEQGPACTDDDECEL--GTCDCHPAADCINLPGSFQCR-CRDGWR 467
GSF C CP G+ G C D +ECE+ G C P +C+N PGS C+ C G++
Sbjct: 285 GSFYCGACPTGWQ---GNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQ 341
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSF-RCLCDTGYKGDGYGLRTVCCVYSCVDI 526
GDG C D C +NGGCHP A+C++T GS C C GY G+GYG CV +
Sbjct: 342 GDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN------GCVQL 395
Query: 527 DE-CANDPTLCENGHCSNTPGGYECDCDVGFT 557
C + P C NG C +T GY C CD G+T
Sbjct: 396 SNICLSHP--CLNGQCIDTVSGYFCKCDSGWT 425
Score = 124 bits (299), Expect = 8e-28
Identities = 114/368 (30%), Positives = 149/368 (40%), Gaps = 56/368 (15%)
Query: 201 VDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGI---CSN 257
VD C+ N GG C+N SF C C + P L D++EC I SG C N
Sbjct: 131 VDKKVCSSNPCQ-NGGTCLNLHDSFFCICPPQWK-GP--LCSADVNECEIYSGTPLSCQN 186
Query: 258 -GACENQMGTYQCVC-DEGYAQSTVKSHXXXXXXXXXXXXR--CQHSCVNTPG--SYHCT 311
G C N MG+Y C C E Y + C+ G Y C
Sbjct: 187 GGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 312 CREGWHLRADGRSCR-DIDECAGGARPCGG-GQCRNTVGSYTCTCTDGLVPSA-AGAKPT 368
C GW + +C D DEC+ PC QC NT GS+ C G P+ G
Sbjct: 247 CDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYC----GACPTGWQGNGYI 302
Query: 369 CQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQ-CPDGYSVKPE 427
C+DI+EC ++ SV P + C NT GS CQ CP GY
Sbjct: 303 CEDINEC----------EINNGGCSVAPPV-------ECVNTPGSSHCQACPPGYQ---G 342
Query: 428 QGPACTDDDECELGTCDCHPAADCINLPGSFQ-CRCRDGWRGDGATCEDVDECLTNNGGC 486
G CT D C + CHP A C + GS C C G+ G+G + L+N
Sbjct: 343 DGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQ-LSNICLS 401
Query: 487 HP--RATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNT 544
HP C +T + C CD+G+ G V C +I+EC ++P L G C +
Sbjct: 402 HPCLNGQCIDTVSGYFCKCDSGWTG-------VNCT---ENINECLSNPCL-NGGTCVDG 450
Query: 545 PGGYECDC 552
+ C+C
Sbjct: 451 VDSFSCEC 458
Score = 115 bits (276), Expect = 5e-25
Identities = 113/377 (29%), Positives = 152/377 (40%), Gaps = 68/377 (18%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGV---C-GDGDC 176
C++ P G G C NL F C C P + K C DVNECEI G C G C
Sbjct: 136 CSSNPCQNG-GTCLNLHDSFFCICPPQW----KGPLCSADVNECEIYSGTPLSCQNGGTC 190
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVD-IDECADND-ALCRGGRCVN----TAG--SFRCE 228
NT GS++CHC P + + C D+C A C G C + AG + C
Sbjct: 191 VNTMGSYSCHCPP----ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 229 CGHGMELAPDRLSCK-DIDECSITSGICSN-GACENQMGTYQC-VCDEGYAQS--TVKSH 283
C G +P+ +C D DECS G CS C N G++ C C G+ + +
Sbjct: 247 CDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDI 306
Query: 284 XXXXXXXXXXXXRCQHSCVNTPGSYHC-TCREGWHLRADGRSCRDIDECA---GGARPCG 339
CVNTPGS HC C G+ + DGR C D C+ GG P
Sbjct: 307 NECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRVCTLTDICSVSNGGCHP-- 362
Query: 340 GGQCRNTVGSY-TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQI 398
C +T+GS CTC G + G Q + C +
Sbjct: 363 DASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNIC----------------------L 400
Query: 399 PELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGS 457
C G C +T+ + C+C G++ G CT++ +EC + C C++ S
Sbjct: 401 SHPCLNGQCIDTVSGYFCKCDSGWT-----GVNCTENINECL--SNPCLNGGTCVDGVDS 453
Query: 458 FQCRCRDGWRGDGATCE 474
F C C W GA C+
Sbjct: 454 FSCECTRLW--TGALCQ 468
Score = 109 bits (262), Expect = 3e-23
Identities = 105/355 (29%), Positives = 136/355 (38%), Gaps = 54/355 (15%)
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDEC---ADNDALCR-GGRCVNTAGSFRCEC 229
G C N SF C C P +K S D++EC + C+ GG CVNT GS+ C C
Sbjct: 145 GTCLNLHDSFFCICPPQWKGPLCS---ADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHC 201
Query: 230 ---GHGMELAPDRLSCKDIDECSITSGICSNGACENQMG--TYQCVCDEGYAQS-TVKSH 283
+G + A C+ GIC + Q G Y CVCD G+ S +
Sbjct: 202 PPETYGPQCASKYDDCEGGSVARCVHGICED-LMREQAGEPKYSCVCDAGWMFSPNSPAC 260
Query: 284 XXXXXXXXXXXXRCQH--SCVNTPGSYHC-TCREGWHLRADGRSCRDIDECA---GGARP 337
C C NT GS++C C GW + +G C DI+EC GG
Sbjct: 261 TLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGW--QGNGYICEDINECEINNGGCSV 318
Query: 338 CGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ 397
+C NT GS C P G C D C SV D
Sbjct: 319 APPVECVNTPGSSHC---QACPPGYQGDGRVCTLTDIC----------SVSNGGCHPD-- 363
Query: 398 IPELCGAGSCHNTIGSF-VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPA--ADCINL 454
SC +T+GS +C C GY+ C C HP CI+
Sbjct: 364 -------ASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLS----NICLSHPCLNGQCIDT 412
Query: 455 PGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
+ C+C GW G T E+++ECL+N C TC + SF C C + G
Sbjct: 413 VSGYFCKCDSGWTGVNCT-ENINECLSN--PCLNGGTCVDGVDSFSCECTRLWTG 464
Score = 97.5 bits (232), Expect = 1e-19
Identities = 79/257 (30%), Positives = 105/257 (40%), Gaps = 20/257 (7%)
Query: 118 EVNECAAFPGL---CGHG-RCRNLLGGFTCDCFP---GYEKDSKNHTCVDVNECEIVDGV 170
+VNEC + G C +G C N +G ++C C P G + SK C + V G+
Sbjct: 170 DVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI 229
Query: 171 CGDGDCHNT-EGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRG-GRCVNTAGSFRC 227
C D E ++C C G+ S C +D DEC+ C +C NT GSF C
Sbjct: 230 CEDLMREQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYC 289
Query: 228 -ECGHGMELAPDRLSCKDIDECSITSGICSNGA---CENQMGTYQC-VCDEGYAQSTVKS 282
C G + + C+DI+EC I +G CS C N G+ C C GY
Sbjct: 290 GACPTGWQ--GNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVC 347
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGSYH-CTCREGWHLRADG-RSCRDIDECAGGARPCGG 340
SC +T GS CTC G+ G C + + PC
Sbjct: 348 TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICL-SHPCLN 406
Query: 341 GQCRNTVGSYTCTCTDG 357
GQC +TV Y C C G
Sbjct: 407 GQCIDTVSGYFCKCDSG 423
Score = 84.6 bits (200), Expect = 8e-16
Identities = 82/257 (31%), Positives = 101/257 (39%), Gaps = 59/257 (22%)
Query: 328 IDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMM 385
+D+ + PC GG C N S+ C C P G P C D++EC T
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICP----PQWKG--PLCSADVNECEIYSGT---- 180
Query: 386 SVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPE-QGPACTDD-DECELGT 442
P C G+C NT+GS+ C CP PE GP C D+CE G+
Sbjct: 181 -------------PLSCQNGGTCVNTMGSYSCHCP------PETYGPQCASKYDDCEGGS 221
Query: 443 CDCHPAADCINL------PGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCA 493
C +L + C C GW A D DEC G C C
Sbjct: 222 VARCVHGICEDLMREQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCF 281
Query: 494 NTDGSFRC-LCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG---HCSNTPGGYE 549
NT GSF C C TG++G+G Y C DI+EC + C C NTPG
Sbjct: 282 NTQGSFYCGACPTGWQGNG---------YICEDINECEINNGGCSVAPPVECVNTPGSSH 332
Query: 550 CD-CDVGFTRAADGRSC 565
C C G+ DGR C
Sbjct: 333 CQACPPGY--QGDGRVC 347
Score = 81.0 bits (191), Expect = 1e-14
Identities = 62/211 (29%), Positives = 91/211 (43%), Gaps = 21/211 (9%)
Query: 117 MEVNECAAFPGLCGH-GRCRNLLGGFTCDCFP-GYEKDSKNHTCVDVNECEIVDGVCGDG 174
++ +EC+ PG C +C N G F C P G++ + C D+NECEI +G C
Sbjct: 262 LDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQ--GNGYICEDINECEINNGGCSVA 319
Query: 175 ---DCHNTEGSFTCH-CRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR-CE 228
+C NT GS C C PGY+ D ++C D C+ ++ C C +T GS C
Sbjct: 320 PPVECVNTPGSSHCQACPPGYQGD--GRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCT 377
Query: 229 C--GH-GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXX 285
C G+ G P+ C + + S C NG C + + Y C CD G+ +
Sbjct: 378 CLPGYTGNGYGPN--GCVQLSNICL-SHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENIN 434
Query: 286 XXXXXXXXXXRCQHSCVNTPGSYHCTCREGW 316
+CV+ S+ C C W
Sbjct: 435 ECLSNPCLNG---GTCVDGVDSFSCECTRLW 462
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 14/83 (16%)
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC---A 530
+ VD+ + ++ C TC N SF C+C +KG +C D++EC +
Sbjct: 129 QTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKG------PLC----SADVNECEIYS 178
Query: 531 NDPTLCEN-GHCSNTPGGYECDC 552
P C+N G C NT G Y C C
Sbjct: 179 GTPLSCQNGGTCVNTMGSYSCHC 201
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 150 bits (363), Expect = 1e-35
Identities = 143/502 (28%), Positives = 204/502 (40%), Gaps = 85/502 (16%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD--------------SKNHTCVD 160
+ +VNEC PG C G C N LG F C C G E S TC
Sbjct: 191 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQL 250
Query: 161 VNE-------CEIVDGVCGDGDCHNTEGSFTCHCRPGYKADD----FSKIC--------- 200
+ E C G G G N + + C+ G D ++ +C
Sbjct: 251 MPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 310
Query: 201 -VDIDEC-ADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKD-IDECSITSGICS 256
D+DEC A CR GG C N+AGSF C C G SC++ +D+C I +
Sbjct: 311 SEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDC-IAATCAP 365
Query: 257 NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGW 316
C +++G++ C+C G ++ + H Q S GS C C+ G+
Sbjct: 366 GSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 423
Query: 317 HLRADGRSC-RDIDEC---AGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGA------ 365
G +C +D+DEC G PC GG C NT GS+ C C G S A
Sbjct: 424 ----SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECL 479
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSV-DPQIPELCGA-----GSCHNTIGSFVCQCP 419
C C DL++T + L+ + + + E A CH+ + F C C
Sbjct: 480 SQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICL 539
Query: 420 DGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVD 477
G+S G C +D DEC + C C + PG+F C+C G+ +G C+ +VD
Sbjct: 540 PGFS-----GTRCEEDIDECR--SSPCANGGQCQDQPGAFHCKCLPGF--EGPRCQTEVD 590
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDP---- 533
ECL++ C A+C + G+F CLC +G+ G + +C C C +
Sbjct: 591 ECLSD--PCPVGASCLDLPGAFFCLCPSGFTGQLCEV-PLCAPNLCQPKQICKDQKDKAN 647
Query: 534 TLCENGHCSNTPGGYECDCDVG 555
LC +G P C C G
Sbjct: 648 CLCPDGSPGCAPPEDNCTCHHG 669
Score = 145 bits (351), Expect = 4e-34
Identities = 135/465 (29%), Positives = 192/465 (41%), Gaps = 70/465 (15%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGV-CGDGD-CHNTEGSFTCHCRP 189
G C++ L +TC C P E + DV+ECE C +G C N+ GSF C C
Sbjct: 288 GTCQDGLDTYTCLC-P--ETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVS 344
Query: 190 GYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC 248
G+ + ++D+C A C G C++ GSF C C G L C D C
Sbjct: 345 GWGGTSCEE---NLDDCIA--ATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMC 395
Query: 249 SITSGICSNGACENQ--MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SCVNT 304
++ + C G+ C+C GY+ T C+H SC+NT
Sbjct: 396 -LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 454
Query: 305 PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTCTDGL---- 358
PGS++C C G+ G C D +EC ++PC G C + + ++ C C GL
Sbjct: 455 PGSFNCLCPPGY----TGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPGLEGQL 508
Query: 359 --VPSAAGAKPTCQDIDECADLISTIIMM-----SVDELQKSVDPQIPELCG-AGSCHNT 410
V + A C + +C DL++ + S ++ +D C G C +
Sbjct: 509 CEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQ 568
Query: 411 IGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
G+F C+C G+ +GP C T+ DEC C A C++LPG+F C C G+ G
Sbjct: 569 PGAFHCKCLPGF-----EGPRCQTEVDECLSDPCPV--GASCLDLPGAFFCLCPSGFTGQ 621
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY------SC 523
CE V C N C P+ C + CLC G G C + SC
Sbjct: 622 --LCE-VPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 676
Query: 524 V-DI----DECANDPTLC------ENGHCSNTPGGYECDCDVGFT 557
V D+ EC + C G C P GY C C G+T
Sbjct: 677 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 721
Score = 139 bits (336), Expect = 3e-32
Identities = 128/464 (27%), Positives = 181/464 (39%), Gaps = 75/464 (16%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++E NECA+ P L H C +LL GF C C PG+ S D++EC G G
Sbjct: 510 EVETNECASAPCL-NHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRSSPCANG-GQ 564
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME- 234
C + G+F C C PG++ + ++DEC +D G C++ G+F C C G
Sbjct: 565 CQDQPGAFHCKCLPGFEG---PRCQTEVDECL-SDPCPVGASCLDLPGAFFCLCPSGFTG 620
Query: 235 -------LAPDRLSCKDI--DECSITSGICSNGACENQMGTYQCVCDEGYAQSTV----- 280
AP+ K I D+ + +C +G+ C C G+ Q +
Sbjct: 621 QLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDV 680
Query: 281 --KSHXXXXXXXXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGA 335
C H +C P Y+CTC G+ G +C ++ C G
Sbjct: 681 GWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSG- 735
Query: 336 RPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV 394
PC GG C + G Y CTC PS G P C Q S
Sbjct: 736 -PCLNGGSCNPSPGGYYCTCP----PSHTG--PQC---------------------QTST 767
Query: 395 DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCIN 453
D + C G+C N G+F C C G+ QGP C C A C +
Sbjct: 768 DYCVSAPCFNGGTCVNRPGTFSCLCAMGF-----QGPRCEGKLRPSCADSPCRNRATCQD 822
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
P +C C G+ G +C+ + + L C + C T SF CLC G+ G
Sbjct: 823 SPQGPRCLCPTGY--TGGSCQTLMD-LCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCN 879
Query: 514 LRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
L C + + + + +LC NG C ++ Y C C GF
Sbjct: 880 LPLSSCQKAA--LSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 921
Score = 136 bits (330), Expect = 1e-31
Identities = 128/457 (28%), Positives = 179/457 (39%), Gaps = 72/457 (15%)
Query: 130 GHGRCRN--LLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVD---GVCGDG-DCHNTEGS 182
G +C L G C C PGY TC D++EC + C G C NT GS
Sbjct: 402 GDAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGS 457
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLS 241
F C C PGY S+ D +EC C G C++ +F C C G+E +L
Sbjct: 458 FNCLCPPGYTG---SRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE---GQLC 509
Query: 242 CKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
+ +EC+ S C N A C + + +QC+C G++ + +
Sbjct: 510 EVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG---Q 564
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C + PG++HC C G+ +G C+ ++DEC P G C + G++ C C G
Sbjct: 565 CQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGAS-CLDLPGAFFCLCPSGFT 619
Query: 360 PSAAG----AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
A CQ C D + D P+ C G C +
Sbjct: 620 GQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSS---- 675
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD---CINLPGSFQCRCRDGWRGDGAT 472
C C G++ GP C E ELG C P A C P + C C G+ G T
Sbjct: 676 CVCDVGWT-----GPEC----EAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGP--T 724
Query: 473 C-EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
C E++ C ++G C +C + G + C C + G T CV + C N
Sbjct: 725 CSEEMTAC--HSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA-----PCFN 777
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
G C N PG + C C +GF G C GK
Sbjct: 778 ------GGTCVNRPGTFSCLCAMGF----QGPRCEGK 804
Score = 136 bits (328), Expect = 3e-31
Identities = 132/448 (29%), Positives = 176/448 (39%), Gaps = 78/448 (17%)
Query: 126 PGLCG-HGRCRNLLGGFT-CDCFPGY--EKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
P C GRC G C C PG+ E+ C N C V+G G C T
Sbjct: 123 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-SANPC--VNG----GVCLATYP 175
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRL 240
CHC PG++ + D++EC + C +G C NT GSF+C C G E L
Sbjct: 176 QIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCEL 232
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH- 299
++G E + C+C G+ + + +CQ+
Sbjct: 233 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSH-----QCQNG 287
Query: 300 -SCVNTPGSYHCTCREGWHLRADGRSC-RDIDEC-AGGARPC-GGGQCRNTVGSYTCTCT 355
+C + +Y C C E W G C D+DEC A G C GG C+N+ GS+ C C
Sbjct: 288 GTCQDGLDTYTCLCPETW----TGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCV 343
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSF 414
G G +++D+C I C GS C + +GSF
Sbjct: 344 SGW-----GGTSCEENLDDC----------------------IAATCAPGSTCIDRVGSF 376
Query: 415 VCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP--GSFQCRCRDGWRGDGAT 472
C CP G + G C +D C + CH A C P GS C C+ G+ G T
Sbjct: 377 SCLCPPGRT-----GLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLCQPGY--SGPT 427
Query: 473 C-EDVDECLTNNGG---CHPRATCANTDGSFRCLCDTGYKGDGYGL-RTVCCVYSCVDID 527
C +D+DECL G C +C NT GSF CLC GY G C C
Sbjct: 428 CHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 487
Query: 528 ECANDPTLCENGHCSNTPG--GYECDCD 553
C + L HC PG G C+ +
Sbjct: 488 TCLD---LLATFHCLCPPGLEGQLCEVE 512
Score = 118 bits (283), Expect = 7e-26
Identities = 127/459 (27%), Positives = 173/459 (37%), Gaps = 86/459 (18%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVD-VNECEIVDGVC-G 172
+ E+ C + P C HG C G+ C C GY TC + + C G C
Sbjct: 688 EAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEMTACH--SGPCLN 739
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
G C+ + G + C C P + D C GG CVN G+F C C G
Sbjct: 740 GGSCNPSPGGYYCTCPPSHTGPQCQ---TSTDYCVSAPCF-NGGTCVNRPGTFSCLCAMG 795
Query: 233 MELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
+ P C+ S C N A C++ +C+C GY + ++
Sbjct: 796 FQ-GP---RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT--LMDLCAQ 849
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWH---LRADGRSCRD--IDECAGGARPC-GGGQCRN 345
R H C+ T S+HC C +GW SC+ + + + C GG C +
Sbjct: 850 KPCPRNSH-CLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVD 908
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
+ SY C C G S CQD V+P C G
Sbjct: 909 SGPSYFCHCPPGFQGS------LCQD---------------------HVNPCESRPCQNG 941
Query: 406 -SCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCR 463
+C ++CQC GY G C+ + D C+ + CH C PG F C C
Sbjct: 942 ATCMAQPSGYLCQCAPGY-----DGQNCSKELDACQ--SQPCHNHGTCTPKPGGFHCACP 994
Query: 464 DGWRGDGATCE-DVDECLTNNGGCHPRAT--CANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
G+ G CE DVDECL + CHP T C + +F C C G+ G
Sbjct: 995 PGF--VGLRCEGDVDECL--DQPCHPTGTAACHSLANAFYCQCLPGHTGQ---------- 1040
Query: 521 YSCVDIDECANDPTLCENGHCSNTPG---GYECDCDVGF 556
+ V+ID C + P G C T G G+ C C GF
Sbjct: 1041 WCEVEIDPCHSQPCF-HGGTCEATAGSPLGFICHCPKGF 1078
Score = 111 bits (268), Expect = 5e-24
Identities = 109/436 (25%), Positives = 164/436 (37%), Gaps = 70/436 (16%)
Query: 129 CGHGRCRNLLGGFTCDC-FPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
C HG C+ CD + G E +++ C+ C G C+ + C C
Sbjct: 666 CHHGHCQR--SSCVCDVGWTGPECEAELGGCISA-PC------AHGGTCYPQPSGYNCTC 716
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDE 247
GY S+ ++ C L GG C + G + C C P C+ +
Sbjct: 717 PTGYTGPTCSE---EMTACHSGPCL-NGGSCNPSPGGYYCTCPPS-HTGPQ---CQTSTD 768
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
+++ + G C N+ GT+ C+C G+ + R +C ++P
Sbjct: 769 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA--TCQDSPQG 826
Query: 308 YHCTCREGWHLRADGRSCRDI-DECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGA 365
C C G+ G SC+ + D CA +PC C T S+ C C G
Sbjct: 827 PRCLCPTGY----TGGSCQTLMDLCA--QKPCPRNSHCLQTGPSFHCLCLQGWTG----- 875
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSV 424
P C + + S + S + LC G C ++ S+ C CP G+
Sbjct: 876 -PLCN-----------LPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF-- 921
Query: 425 KPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTN 482
QG C D + CE + C A C+ P + C+C G+ DG C +++D C +
Sbjct: 922 ---QGSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPGY--DGQNCSKELDACQSQ 974
Query: 483 NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT-LCENGHC 541
CH TC G F C C G+ GLR C D+DEC + P C
Sbjct: 975 P--CHNHGTCTPKPGGFHCACPPGF----VGLR---CE---GDVDECLDQPCHPTGTAAC 1022
Query: 542 SNTPGGYECDCDVGFT 557
+ + C C G T
Sbjct: 1023 HSLANAFYCQCLPGHT 1038
Score = 73.3 bits (172), Expect = 2e-12
Identities = 115/474 (24%), Positives = 161/474 (33%), Gaps = 82/474 (17%)
Query: 131 HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN------TEGSFT 184
+ C F C C G+ N + + G+ CHN + S+
Sbjct: 855 NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF 914
Query: 185 CHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC-K 243
CHC PG++ +C D ++ G C+ + C+C G D +C K
Sbjct: 915 CHCPPGFQGS----LCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY----DGQNCSK 966
Query: 244 DIDECSITSGICSN-GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
++D C S C N G C + G + C C G+ + +C
Sbjct: 967 ELDACQ--SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTA-ACH 1023
Query: 303 NTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGS---YTCTCTDG 357
+ +++C C G H G+ C +ID C ++PC GG C T GS + C C G
Sbjct: 1024 SLANAFYCQCLPG-HT---GQWCEVEIDPCH--SQPCFHGGTCEATAGSPLGFICHCPKG 1077
Query: 358 LV-PSAAGAKPTCQDIDEC-----------ADLISTIIMMSVDELQKSVDPQIPELCGA- 404
P+ + P+C C +S + P P+ CG
Sbjct: 1078 FEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 1136
Query: 405 ------GSCHNTIG----SFVCQCPDGYSVKPEQGPACTD-DDECELGTCDCHPAADCIN 453
GSC T G F C CP Q P + G CD + N
Sbjct: 1137 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1196
Query: 454 LPGSFQCRCR--DGWRGDGATCEDVDEC--LTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G C D W+G C C L +G CHP+ S CL D
Sbjct: 1197 WDGG-DCSLGVPDPWKG----CPSHSRCWLLFRDGQCHPQCD------SEECLFD----- 1240
Query: 510 DGYGLRTV-CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADG 562
GY T C + D+ +D NGHC EC D G R DG
Sbjct: 1241 -GYDCETPPACTPA---YDQYCHDHF--HNGHCEKGCNTAECGWDGGDCRPEDG 1288
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/230 (27%), Positives = 87/230 (37%), Gaps = 37/230 (16%)
Query: 331 CAGGARPCG-GGQCRN-TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
C PC GG C + ++G TC C G + CQ+ C + S ++
Sbjct: 27 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 86
Query: 389 -ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHP 447
L S P P SF+C C G++ + Q +D C C
Sbjct: 87 LGLPSSPSPLTP-------------SFLCTCLPGFTGERCQAKL---EDPCPPSFCSKRG 130
Query: 448 AADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
I G QC C GW G+ C+ D C N C C T +C C G+
Sbjct: 131 RCH-IQASGRPQCSCMPGWTGE--QCQLRDFCSANP--CVNGGVCLATYPQIQCHCPPGF 185
Query: 508 KGDGYGLRTVCCVYSCV-DIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
+G ++C D++EC DP C G C NT G ++C C VG
Sbjct: 186 EG-----------HACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 224
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/168 (32%), Positives = 66/168 (39%), Gaps = 14/168 (8%)
Query: 392 KSVDPQIPELCGA-GSCH-NTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAA 449
K DP P C G CH G C C G++ G C D C C
Sbjct: 116 KLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWT-----GEQCQLRDFCSANPCV--NGG 168
Query: 450 DCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
C+ QC C G+ +G CE DV+EC + G C +C NT GSF+CLC G +
Sbjct: 169 VCLATYPQIQCHCPPGF--EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 226
Query: 509 GDGYGLRT-VCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDV 554
G LR C C + C P H C PG C+V
Sbjct: 227 GPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEV 274
>DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module containing
mucin-like hormone receptor-like 1 protein.
Length = 886
Score = 150 bits (363), Expect = 1e-35
Identities = 100/315 (31%), Positives = 135/315 (42%), Gaps = 52/315 (16%)
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGW-------HLRADGRSC 325
EG+ + T K + +C NT SY+C C++G+ H + G C
Sbjct: 19 EGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRC 78
Query: 326 RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAG----AKP---TCQDIDECAD 377
+DIDEC+ +PCG C+N G Y C+C DG KP +C DI+EC
Sbjct: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-- 136
Query: 378 LISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
L SV P+ + C N++GS+ C C G+ + C D DE
Sbjct: 137 ------------LTSSVCPEHSD------CVNSMGSYSCSCQVGFI---SRNSTCEDVDE 175
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGW---------RGDGATCEDVDECLTNNGGCHP 488
C C A C N G++ C C G+ +G A+CED+DEC C
Sbjct: 176 CADPRA-CPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEM---CPI 231
Query: 489 RATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGG 547
+TC NT GS+ C C G+ L C DIDEC DP+ C N C+N G
Sbjct: 232 NSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGS 291
Query: 548 YECDCDVGFTRAADG 562
Y C C GF +G
Sbjct: 292 YSCGCIAGFHPNPEG 306
Score = 136 bits (329), Expect = 2e-31
Identities = 82/273 (30%), Positives = 115/273 (42%), Gaps = 38/273 (13%)
Query: 128 LC-GHGRCRNLLGGFTCDCFPGY-EKDSKNH------TCVDVNECEIVDGVCG-DGDCHN 178
LC + C N + + C C G+ + +NH C D++EC CG + C N
Sbjct: 40 LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 99
Query: 179 TEGSFTCHCRPGY-----------KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC 227
G + C C G+ K +FS C DI+EC + CVN+ GS+ C
Sbjct: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFS--CTDINECLTSSVCPEHSDCVNSMGSYSC 157
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXX 287
C G +C+D+DEC+ + C N +G Y C C+ G+ S+
Sbjct: 158 SCQVGF--ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGL 215
Query: 288 XXXXXXXXRCQH------SCVNTPGSYHCTCREGW-------HLRADGRSCRDIDECAGG 334
C +C NTPGSY CTC G+ + G CRDIDEC
Sbjct: 216 KASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQD 275
Query: 335 ARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAK 366
CG C N +GSY+C C G P+ G++
Sbjct: 276 PSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 308
Score = 129 bits (312), Expect = 2e-29
Identities = 91/293 (31%), Positives = 123/293 (41%), Gaps = 55/293 (18%)
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGM-------ELAPDRLSCKDIDECSITSGICS 256
+ C D+ C NT S+ C C G + CKDIDECS + C
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
Query: 257 -NGACENQMGTYQCVCDEGYAQSTVK--------SHXXXXXXXXXXXXRC-QHS-CVNTP 305
N +C+N G Y+C C +G++ T + C +HS CVN+
Sbjct: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 152
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAA-- 363
GSY C+C+ G+ R +C D+DECA C NTVG+Y+C C G S+
Sbjct: 153 GSYSCSCQVGFISR--NSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
Query: 364 ---GAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCP 419
G K +C+DIDEC E+C S C NT GS+ C C
Sbjct: 211 SFQGLKASCEDIDECT-----------------------EMCPINSTCTNTPGSYFCTCH 247
Query: 420 DGYSVK------PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
G++ +QG C D DEC C P + C N GS+ C C G+
Sbjct: 248 PGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
Score = 126 bits (305), Expect = 2e-28
Identities = 74/232 (31%), Positives = 108/232 (46%), Gaps = 32/232 (13%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNH---------TCVDVNECEIV 167
+++EC+ P CG + C+NL G + C C G+ + N +C D+NEC +
Sbjct: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LT 138
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFR 226
VC + DC N+ GS++C C+ G+ + + + C D+DECAD A C NT G++
Sbjct: 139 SSVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECADPRACPEHATCNNTVGNYS 196
Query: 227 CECGHGMELAPDRL-------SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQST 279
C C G E + L SC+DIDEC+ I N C N G+Y C C G+A S
Sbjct: 197 CFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPSN 254
Query: 280 VKSHXXXXXXXXXXXXRCQHS---------CVNTPGSYHCTCREGWHLRADG 322
+ + C+ C N GSY C C G+H +G
Sbjct: 255 GQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
Score = 103 bits (246), Expect = 2e-21
Identities = 63/186 (33%), Positives = 88/186 (47%), Gaps = 30/186 (16%)
Query: 401 LCGA-GSCHNTIGSFVCQCPDGYSVKPEQ------GPACTDDDECELGTCDCHPAADCIN 453
LC A +C NT+ S+ C C G+ Q G C D DEC C P + C N
Sbjct: 40 LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 99
Query: 454 LPGSFQCRCRDG--------W---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
L G ++C C DG W + +C D++ECLT++ C + C N+ GS+ C
Sbjct: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSV-CPEHSDCVNSMGSYSCS 158
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAAD 561
C G+ + +C D+DECA DP C E+ C+NT G Y C C+ GF ++
Sbjct: 159 CQVGF---------ISRNSTCEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSG 208
Query: 562 GRSCLG 567
S G
Sbjct: 209 HLSFQG 214
>BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein.
Length = 821
Score = 150 bits (363), Expect = 1e-35
Identities = 100/315 (31%), Positives = 135/315 (42%), Gaps = 52/315 (16%)
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGW-------HLRADGRSC 325
EG+ + T K + +C NT SY+C C++G+ H + G C
Sbjct: 19 EGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRC 78
Query: 326 RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAG----AKP---TCQDIDECAD 377
+DIDEC+ +PCG C+N G Y C+C DG KP +C DI+EC
Sbjct: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-- 136
Query: 378 LISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
L SV P+ + C N++GS+ C C G+ + C D DE
Sbjct: 137 ------------LTSSVCPEHSD------CVNSMGSYSCSCQVGFI---SRNSTCEDVDE 175
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGW---------RGDGATCEDVDECLTNNGGCHP 488
C C A C N G++ C C G+ +G A+CED+DEC C
Sbjct: 176 CADPRA-CPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEM---CPI 231
Query: 489 RATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGG 547
+TC NT GS+ C C G+ L C DIDEC DP+ C N C+N G
Sbjct: 232 NSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGS 291
Query: 548 YECDCDVGFTRAADG 562
Y C C GF +G
Sbjct: 292 YSCGCIAGFHPNPEG 306
Score = 136 bits (329), Expect = 2e-31
Identities = 82/273 (30%), Positives = 115/273 (42%), Gaps = 38/273 (13%)
Query: 128 LC-GHGRCRNLLGGFTCDCFPGY-EKDSKNH------TCVDVNECEIVDGVCG-DGDCHN 178
LC + C N + + C C G+ + +NH C D++EC CG + C N
Sbjct: 40 LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 99
Query: 179 TEGSFTCHCRPGY-----------KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC 227
G + C C G+ K +FS C DI+EC + CVN+ GS+ C
Sbjct: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFS--CTDINECLTSSVCPEHSDCVNSMGSYSC 157
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXX 287
C G +C+D+DEC+ + C N +G Y C C+ G+ S+
Sbjct: 158 SCQVGF--ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGL 215
Query: 288 XXXXXXXXRCQH------SCVNTPGSYHCTCREGW-------HLRADGRSCRDIDECAGG 334
C +C NTPGSY CTC G+ + G CRDIDEC
Sbjct: 216 KASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQD 275
Query: 335 ARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAK 366
CG C N +GSY+C C G P+ G++
Sbjct: 276 PSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 308
Score = 129 bits (312), Expect = 2e-29
Identities = 91/293 (31%), Positives = 123/293 (41%), Gaps = 55/293 (18%)
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGM-------ELAPDRLSCKDIDECSITSGICS 256
+ C D+ C NT S+ C C G + CKDIDECS + C
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
Query: 257 -NGACENQMGTYQCVCDEGYAQSTVK--------SHXXXXXXXXXXXXRC-QHS-CVNTP 305
N +C+N G Y+C C +G++ T + C +HS CVN+
Sbjct: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 152
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAA-- 363
GSY C+C+ G+ R +C D+DECA C NTVG+Y+C C G S+
Sbjct: 153 GSYSCSCQVGFISR--NSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
Query: 364 ---GAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCP 419
G K +C+DIDEC E+C S C NT GS+ C C
Sbjct: 211 SFQGLKASCEDIDECT-----------------------EMCPINSTCTNTPGSYFCTCH 247
Query: 420 DGYSVK------PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
G++ +QG C D DEC C P + C N GS+ C C G+
Sbjct: 248 PGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
Score = 126 bits (305), Expect = 2e-28
Identities = 74/232 (31%), Positives = 108/232 (46%), Gaps = 32/232 (13%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNH---------TCVDVNECEIV 167
+++EC+ P CG + C+NL G + C C G+ + N +C D+NEC +
Sbjct: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LT 138
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFR 226
VC + DC N+ GS++C C+ G+ + + + C D+DECAD A C NT G++
Sbjct: 139 SSVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECADPRACPEHATCNNTVGNYS 196
Query: 227 CECGHGMELAPDRL-------SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQST 279
C C G E + L SC+DIDEC+ I N C N G+Y C C G+A S
Sbjct: 197 CFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPSN 254
Query: 280 VKSHXXXXXXXXXXXXRCQHS---------CVNTPGSYHCTCREGWHLRADG 322
+ + C+ C N GSY C C G+H +G
Sbjct: 255 GQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
Score = 103 bits (246), Expect = 2e-21
Identities = 63/186 (33%), Positives = 88/186 (47%), Gaps = 30/186 (16%)
Query: 401 LCGA-GSCHNTIGSFVCQCPDGYSVKPEQ------GPACTDDDECELGTCDCHPAADCIN 453
LC A +C NT+ S+ C C G+ Q G C D DEC C P + C N
Sbjct: 40 LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 99
Query: 454 LPGSFQCRCRDG--------W---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
L G ++C C DG W + +C D++ECLT++ C + C N+ GS+ C
Sbjct: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSV-CPEHSDCVNSMGSYSCS 158
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAAD 561
C G+ + +C D+DECA DP C E+ C+NT G Y C C+ GF ++
Sbjct: 159 CQVGF---------ISRNSTCEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSG 208
Query: 562 GRSCLG 567
S G
Sbjct: 209 HLSFQG 214
>AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane helix
receptor protein.
Length = 929
Score = 150 bits (363), Expect = 1e-35
Identities = 100/315 (31%), Positives = 135/315 (42%), Gaps = 52/315 (16%)
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGW-------HLRADGRSC 325
EG+ + T K + +C NT SY+C C++G+ H + G C
Sbjct: 37 EGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRC 96
Query: 326 RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAG----AKP---TCQDIDECAD 377
+DIDEC+ +PCG C+N G Y C+C DG KP +C DI+EC
Sbjct: 97 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-- 154
Query: 378 LISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
L SV P+ + C N++GS+ C C G+ + C D DE
Sbjct: 155 ------------LTSSVCPEHSD------CVNSMGSYSCSCQVGFI---SRNSTCEDVDE 193
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGW---------RGDGATCEDVDECLTNNGGCHP 488
C C A C N G++ C C G+ +G A+CED+DEC C
Sbjct: 194 CADPRA-CPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEM---CPI 249
Query: 489 RATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGG 547
+TC NT GS+ C C G+ L C DIDEC DP+ C N C+N G
Sbjct: 250 NSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGS 309
Query: 548 YECDCDVGFTRAADG 562
Y C C GF +G
Sbjct: 310 YSCGCIAGFHPNPEG 324
Score = 136 bits (329), Expect = 2e-31
Identities = 82/273 (30%), Positives = 115/273 (42%), Gaps = 38/273 (13%)
Query: 128 LC-GHGRCRNLLGGFTCDCFPGY-EKDSKNH------TCVDVNECEIVDGVCG-DGDCHN 178
LC + C N + + C C G+ + +NH C D++EC CG + C N
Sbjct: 58 LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 117
Query: 179 TEGSFTCHCRPGY-----------KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC 227
G + C C G+ K +FS C DI+EC + CVN+ GS+ C
Sbjct: 118 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFS--CTDINECLTSSVCPEHSDCVNSMGSYSC 175
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXX 287
C G +C+D+DEC+ + C N +G Y C C+ G+ S+
Sbjct: 176 SCQVGF--ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGL 233
Query: 288 XXXXXXXXRCQH------SCVNTPGSYHCTCREGW-------HLRADGRSCRDIDECAGG 334
C +C NTPGSY CTC G+ + G CRDIDEC
Sbjct: 234 KASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQD 293
Query: 335 ARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAK 366
CG C N +GSY+C C G P+ G++
Sbjct: 294 PSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 326
Score = 130 bits (313), Expect = 2e-29
Identities = 102/330 (30%), Positives = 135/330 (40%), Gaps = 68/330 (20%)
Query: 170 VCGDGDC---HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFR 226
+ G G C H+ EG H RP K + C D C C NT S+
Sbjct: 24 LAGRGGCCVMHSWEG----HIRPTRKPNTKGNNCRDSTLCPAY------ATCTNTVDSYY 73
Query: 227 CECGHGM-------ELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQS 278
C C G + CKDIDECS + C N +C+N G Y+C C +G++
Sbjct: 74 CACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSP 133
Query: 279 TVK--------SHXXXXXXXXXXXXRC-QHS-CVNTPGSYHCTCREGWHLRADGRSCRDI 328
T + C +HS CVN+ GSY C+C+ G+ R +C D+
Sbjct: 134 TGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISR--NSTCEDV 191
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAA-----GAKPTCQDIDECADLISTII 383
DECA C NTVG+Y+C C G S+ G K +C+DIDEC
Sbjct: 192 DECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT------- 244
Query: 384 MMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVK------PEQGPACTDDD 436
E+C S C NT GS+ C C G++ +QG C D D
Sbjct: 245 ----------------EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDID 288
Query: 437 ECELGTCDCHPAADCINLPGSFQCRCRDGW 466
EC C P + C N GS+ C C G+
Sbjct: 289 ECRQDPSTCGPNSICTNALGSYSCGCIAGF 318
Score = 126 bits (305), Expect = 2e-28
Identities = 74/232 (31%), Positives = 108/232 (46%), Gaps = 32/232 (13%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNH---------TCVDVNECEIV 167
+++EC+ P CG + C+NL G + C C G+ + N +C D+NEC +
Sbjct: 98 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LT 156
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFR 226
VC + DC N+ GS++C C+ G+ + + + C D+DECAD A C NT G++
Sbjct: 157 SSVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECADPRACPEHATCNNTVGNYS 214
Query: 227 CECGHGMELAPDRL-------SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQST 279
C C G E + L SC+DIDEC+ I N C N G+Y C C G+A S
Sbjct: 215 CFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPSN 272
Query: 280 VKSHXXXXXXXXXXXXRCQHS---------CVNTPGSYHCTCREGWHLRADG 322
+ + C+ C N GSY C C G+H +G
Sbjct: 273 GQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 324
Score = 103 bits (246), Expect = 2e-21
Identities = 63/186 (33%), Positives = 88/186 (47%), Gaps = 30/186 (16%)
Query: 401 LCGA-GSCHNTIGSFVCQCPDGYSVKPEQ------GPACTDDDECELGTCDCHPAADCIN 453
LC A +C NT+ S+ C C G+ Q G C D DEC C P + C N
Sbjct: 58 LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 117
Query: 454 LPGSFQCRCRDG--------W---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
L G ++C C DG W + +C D++ECLT++ C + C N+ GS+ C
Sbjct: 118 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSV-CPEHSDCVNSMGSYSCS 176
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAAD 561
C G+ + +C D+DECA DP C E+ C+NT G Y C C+ GF ++
Sbjct: 177 CQVGF---------ISRNSTCEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSG 226
Query: 562 GRSCLG 567
S G
Sbjct: 227 HLSFQG 232
>X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein.
Length = 886
Score = 149 bits (362), Expect = 2e-35
Identities = 100/315 (31%), Positives = 136/315 (43%), Gaps = 52/315 (16%)
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGW-------HLRADGRSC 325
EG+ + T K + +C NT SY+CTC++G+ H + G C
Sbjct: 19 EGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRC 78
Query: 326 RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAG----AKP---TCQDIDECAD 377
+DIDEC+ +PCG C+N G Y C+C DG KP +C DI+EC
Sbjct: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-- 136
Query: 378 LISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
L V P+ + C N++GS+ C C G+ + C D +E
Sbjct: 137 ------------LTSRVCPEHSD------CVNSMGSYSCSCQVGFI---SRNSTCEDVNE 175
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGW---------RGDGATCEDVDECLTNNGGCHP 488
C C A C N G++ C C G+ +G A+CED+DEC C
Sbjct: 176 CADPRA-CPEHATCNNTVGNYSCFCNPGFESSSGHLSCQGLKASCEDIDECTEM---CPI 231
Query: 489 RATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGG 547
+TC NT GS+ C C G+ L C DIDEC DP+ C N C+N G
Sbjct: 232 NSTCTNTPGSYFCTCHPGFAPSSGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGS 291
Query: 548 YECDCDVGFTRAADG 562
Y C C VGF +G
Sbjct: 292 YSCGCIVGFHPNPEG 306
Score = 133 bits (321), Expect = 2e-30
Identities = 81/273 (29%), Positives = 115/273 (42%), Gaps = 38/273 (13%)
Query: 128 LC-GHGRCRNLLGGFTCDCFPGY-EKDSKNH------TCVDVNECEIVDGVCG-DGDCHN 178
LC + C N + + C C G+ + +NH C D++EC CG + C N
Sbjct: 40 LCPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 99
Query: 179 TEGSFTCHCRPGY-----------KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRC 227
G + C C G+ K +FS C DI+EC + CVN+ GS+ C
Sbjct: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFS--CTDINECLTSRVCPEHSDCVNSMGSYSC 157
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXX 287
C G +C+D++EC+ + C N +G Y C C+ G+ S+
Sbjct: 158 SCQVGF--ISRNSTCEDVNECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSCQGL 215
Query: 288 XXXXXXXXRCQH------SCVNTPGSYHCTCREGW-------HLRADGRSCRDIDECAGG 334
C +C NTPGSY CTC G+ + G CRDIDEC
Sbjct: 216 KASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSSGQLNFTDQGVECRDIDECRQD 275
Query: 335 ARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAK 366
CG C N +GSY+C C G P+ G++
Sbjct: 276 PSTCGPNSICTNALGSYSCGCIVGFHPNPEGSQ 308
Score = 126 bits (305), Expect = 2e-28
Identities = 90/293 (30%), Positives = 123/293 (41%), Gaps = 55/293 (18%)
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGM-------ELAPDRLSCKDIDECSITSGICS 256
+ C D+ C NT S+ C C G + CKDIDECS + C
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
Query: 257 -NGACENQMGTYQCVCDEGYAQSTVK--------SHXXXXXXXXXXXXRC-QHS-CVNTP 305
N +C+N G Y+C C +G++ T + C +HS CVN+
Sbjct: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSRVCPEHSDCVNSM 152
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAA-- 363
GSY C+C+ G+ R +C D++ECA C NTVG+Y+C C G S+
Sbjct: 153 GSYSCSCQVGFISR--NSTCEDVNECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
Query: 364 ---GAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCP 419
G K +C+DIDEC E+C S C NT GS+ C C
Sbjct: 211 SCQGLKASCEDIDECT-----------------------EMCPINSTCTNTPGSYFCTCH 247
Query: 420 DGYSVK------PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
G++ +QG C D DEC C P + C N GS+ C C G+
Sbjct: 248 PGFAPSSGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIVGF 300
Score = 124 bits (298), Expect = 1e-27
Identities = 73/232 (31%), Positives = 109/232 (46%), Gaps = 32/232 (13%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNH---------TCVDVNECEIV 167
+++EC+ P CG + C+NL G + C C G+ + N +C D+NEC +
Sbjct: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LT 138
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFR 226
VC + DC N+ GS++C C+ G+ + + + C D++ECAD A C NT G++
Sbjct: 139 SRVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVNECADPRACPEHATCNNTVGNYS 196
Query: 227 CECGHGMELAPDRL-------SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQST 279
C C G E + L SC+DIDEC+ I N C N G+Y C C G+A S+
Sbjct: 197 CFCNPGFESSSGHLSCQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPSS 254
Query: 280 VKSHXXXXXXXXXXXXRCQHS---------CVNTPGSYHCTCREGWHLRADG 322
+ + C+ C N GSY C C G+H +G
Sbjct: 255 GQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIVGFHPNPEG 306
Score = 105 bits (251), Expect = 6e-22
Identities = 63/186 (33%), Positives = 88/186 (47%), Gaps = 30/186 (16%)
Query: 401 LCGA-GSCHNTIGSFVCQCPDGYSVKPEQ------GPACTDDDECELGTCDCHPAADCIN 453
LC A +C NT+ S+ C C G+ Q G C D DEC C P + C N
Sbjct: 40 LCPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 99
Query: 454 LPGSFQCRCRDG--------W---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
L G ++C C DG W + +C D++ECLT+ C + C N+ GS+ C
Sbjct: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSRV-CPEHSDCVNSMGSYSCS 158
Query: 503 CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAAD 561
C G+ + +C D++ECA DP C E+ C+NT G Y C C+ GF ++
Sbjct: 159 CQVGF---------ISRNSTCEDVNECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSG 208
Query: 562 GRSCLG 567
SC G
Sbjct: 209 HLSCQG 214
>CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein.
Length = 448
Score = 148 bits (358), Expect = 6e-35
Identities = 81/210 (38%), Positives = 100/210 (47%), Gaps = 10/210 (4%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GY+ D N CVDV+EC C C NTEG +TC C GY + C+DI
Sbjct: 113 CRFGYQMDESNQ-CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ--CLDI 169
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ C N GS+ C C G L D SC+D++EC+ T C C N
Sbjct: 170 DEC--RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECA-TENPCVQ-TCVNT 224
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
G++ C CD GY H CQH CVN PG+Y C+C G+ L D R
Sbjct: 225 YGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNR 284
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTC 352
SC+DI+EC C Q C N G + C
Sbjct: 285 SCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 140 bits (340), Expect = 9e-33
Identities = 100/333 (30%), Positives = 146/333 (43%), Gaps = 39/333 (11%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRC-ECGHGM 233
C + G+ C G+ D S C+DIDEC CRG CVN G + C + +
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
P + A + +C GY Q +
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGY-QMDESNQCVDVDECATD 134
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C + C+NT G Y C+C +G+ L +G+ C DIDEC G C C N GSY+
Sbjct: 135 SHQCNPTQICINTEGGYTCSCTDGYWL-LEGQ-CLDIDECRYGY--CQQ-LCANVPGSYS 189
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
CTC G + G +CQD++ECA + +P + +C NT
Sbjct: 190 CTCNPGFTLNEDGR--SCQDVNECA----------------TENPCVQ------TCVNTY 225
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGD 469
GSF+C+C GY ++ E G C+D DEC C +C+N PG++ C C G+ D
Sbjct: 226 GSFICRCDPGYELE-EDGVHCSDMDECSFSEFLCQH--ECVNQPGTYFCSCPPGYILLDD 282
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+C+D++EC N C+ + TC N G F+C+
Sbjct: 283 NRSCQDINECEHRNHTCNLQQTCYNLQGGFKCI 315
Score = 136 bits (330), Expect = 1e-31
Identities = 99/327 (30%), Positives = 132/327 (40%), Gaps = 38/327 (11%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTC--HCRPGYKADD 195
G C G++ D ++ C+D++EC + C GD C N G + C P Y+
Sbjct: 21 GNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPY 80
Query: 196 FSKICVDIDECADNDALCRGGRCVNT-AGSFRCECGHGMELAPDRLSCKDIDECSITSGI 254
+ A T + C G+ M+ + C D+DEC+ S
Sbjct: 81 SNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMD---ESNQCVDVDECATDSHQ 137
Query: 255 CS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCR 313
C+ C N G Y C C +GY CQ C N PGSY CTC
Sbjct: 138 CNPTQICINTEGGYTCSCTDGY----WLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCN 193
Query: 314 EGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDID 373
G+ L DGRSC+D++ECA PC C NT GS+ C C G G C D+D
Sbjct: 194 PGFTLNEDGRSCQDVNECA-TENPC-VQTCVNTYGSFICRCDPGYELEEDGVH--CSDMD 249
Query: 374 ECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
EC S E LC C N G++ C CP GY + + +C
Sbjct: 250 EC----------SFSEF----------LC-QHECVNQPGTYFCSCPPGY-ILLDDNRSCQ 287
Query: 434 DDDECELGTCDCHPAADCINLPGSFQC 460
D +ECE C+ C NL G F+C
Sbjct: 288 DINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 133 bits (322), Expect = 1e-30
Identities = 95/289 (32%), Positives = 121/289 (41%), Gaps = 42/289 (14%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+ +PG+ C G+ L C DIDEC C G C N G Y C V
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 360 ---------------PSAAGAKP-TCQDIDECADLISTIIMMSVDELQKSVDPQI----P 399
P A A P + + + + +DE + VD
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDS 135
Query: 400 ELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
C C NT G + C C DGY + Q C D DEC G C C N+PGS+
Sbjct: 136 HQCNPTQICINTEGGYTCSCTDGYWLLEGQ---CLDIDECRYGYCQ----QLCANVPGSY 188
Query: 459 QCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
C C G+ DG +C+DV+EC T N TC NT GSF C CD GY+ + G+
Sbjct: 189 SCTCNPGFTLNEDGRSCQDVNECATENPCVQ---TCVNTYGSFICRCDPGYELEEDGVH- 244
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C D+DEC+ LC++ C N PG Y C C G+ D RSC
Sbjct: 245 ------CSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSC 286
Score = 126 bits (305), Expect = 2e-28
Identities = 84/263 (31%), Positives = 114/263 (43%), Gaps = 15/263 (5%)
Query: 117 MEVNECAAFPGLC-GHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGD 173
++++EC P C G C N GG+ C P Y N +
Sbjct: 41 LDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLS 100
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHG 232
+ T S CR GY+ D+ S CVD+DECA + C + C+NT G + C C G
Sbjct: 101 APNYPTI-SRPLICRFGYQMDE-SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDG 158
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
L + C DIDEC G C C N G+Y C C+ G+ +
Sbjct: 159 YWLLEGQ--CLDIDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNE-DGRSCQDVNECA 212
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C +CVNT GS+ C C G+ L DG C D+DEC+ C +C N G+Y C
Sbjct: 213 TENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFC 271
Query: 353 TCTDGLVPSAAGAKPTCQDIDEC 375
+C G + +CQDI+EC
Sbjct: 272 SCPPGYI--LLDDNRSCQDINEC 292
Score = 126 bits (305), Expect = 2e-28
Identities = 69/197 (35%), Positives = 94/197 (47%), Gaps = 11/197 (5%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C N GG+TC C GY C+D++EC G C
Sbjct: 126 VDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDIDECRY--GYC-QQL 180
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS++C C PG+ ++ + C D++ECA + + CVNT GSF C C G EL
Sbjct: 181 CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTYGSFICRCDPGYEL 238
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D + C D+DECS + +C + C NQ GTY C C GY
Sbjct: 239 EEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNH 297
Query: 296 RC--QHSCVNTPGSYHC 310
C Q +C N G + C
Sbjct: 298 TCNLQQTCYNLQGGFKC 314
Score = 117 bits (281), Expect = 1e-25
Identities = 59/164 (35%), Positives = 88/164 (53%), Gaps = 11/164 (6%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC G C C N+ G ++C C PG+ + +C DVNEC + C C
Sbjct: 167 LDIDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC-ATENPCVQ-TC 221
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY+ ++ C D+DEC+ ++ LC+ CVN G++ C C G L
Sbjct: 222 VNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQ-HECVNQPGTYFCSCPPGYILL 280
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV----CDEGY 275
D SC+DI+EC + C+ C N G ++C+ C+E Y
Sbjct: 281 DDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPY 324
>BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein.
Length = 448
Score = 148 bits (358), Expect = 6e-35
Identities = 81/210 (38%), Positives = 100/210 (47%), Gaps = 10/210 (4%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GY+ D N CVDV+EC C C NTEG +TC C GY + C+DI
Sbjct: 113 CRFGYQMDESNQ-CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ--CLDI 169
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ C N GS+ C C G L D SC+D++EC+ T C C N
Sbjct: 170 DEC--RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECA-TENPCVQ-TCVNT 224
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
G++ C CD GY H CQH CVN PG+Y C+C G+ L D R
Sbjct: 225 YGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNR 284
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTC 352
SC+DI+EC C Q C N G + C
Sbjct: 285 SCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 140 bits (340), Expect = 9e-33
Identities = 100/333 (30%), Positives = 146/333 (43%), Gaps = 39/333 (11%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRC-ECGHGM 233
C + G+ C G+ D S C+DIDEC CRG CVN G + C + +
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
P + A + +C GY Q +
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGY-QMDESNQCVDVDECATD 134
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C + C+NT G Y C+C +G+ L +G+ C DIDEC G C C N GSY+
Sbjct: 135 SHQCNPTQICINTEGGYTCSCTDGYWL-LEGQ-CLDIDECRYGY--CQQ-LCANVPGSYS 189
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
CTC G + G +CQD++ECA + +P + +C NT
Sbjct: 190 CTCNPGFTLNEDGR--SCQDVNECA----------------TENPCVQ------TCVNTY 225
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGD 469
GSF+C+C GY ++ E G C+D DEC C +C+N PG++ C C G+ D
Sbjct: 226 GSFICRCDPGYELE-EDGVHCSDMDECSFSEFLCQH--ECVNQPGTYFCSCPPGYILLDD 282
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+C+D++EC N C+ + TC N G F+C+
Sbjct: 283 NRSCQDINECEHRNHTCNLQQTCYNLQGGFKCI 315
Score = 136 bits (330), Expect = 1e-31
Identities = 99/327 (30%), Positives = 132/327 (40%), Gaps = 38/327 (11%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTC--HCRPGYKADD 195
G C G++ D ++ C+D++EC + C GD C N G + C P Y+
Sbjct: 21 GNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPY 80
Query: 196 FSKICVDIDECADNDALCRGGRCVNT-AGSFRCECGHGMELAPDRLSCKDIDECSITSGI 254
+ A T + C G+ M+ + C D+DEC+ S
Sbjct: 81 SNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMD---ESNQCVDVDECATDSHQ 137
Query: 255 CS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCR 313
C+ C N G Y C C +GY CQ C N PGSY CTC
Sbjct: 138 CNPTQICINTEGGYTCSCTDGY----WLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCN 193
Query: 314 EGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDID 373
G+ L DGRSC+D++ECA PC C NT GS+ C C G G C D+D
Sbjct: 194 PGFTLNEDGRSCQDVNECA-TENPC-VQTCVNTYGSFICRCDPGYELEEDGVH--CSDMD 249
Query: 374 ECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
EC S E LC C N G++ C CP GY + + +C
Sbjct: 250 EC----------SFSEF----------LC-QHECVNQPGTYFCSCPPGY-ILLDDNRSCQ 287
Query: 434 DDDECELGTCDCHPAADCINLPGSFQC 460
D +ECE C+ C NL G F+C
Sbjct: 288 DINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 133 bits (322), Expect = 1e-30
Identities = 95/289 (32%), Positives = 121/289 (41%), Gaps = 42/289 (14%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+ +PG+ C G+ L C DIDEC C G C N G Y C V
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 360 ---------------PSAAGAKP-TCQDIDECADLISTIIMMSVDELQKSVDPQI----P 399
P A A P + + + + +DE + VD
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDS 135
Query: 400 ELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
C C NT G + C C DGY + Q C D DEC G C C N+PGS+
Sbjct: 136 HQCNPTQICINTEGGYTCSCTDGYWLLEGQ---CLDIDECRYGYCQ----QLCANVPGSY 188
Query: 459 QCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
C C G+ DG +C+DV+EC T N TC NT GSF C CD GY+ + G+
Sbjct: 189 SCTCNPGFTLNEDGRSCQDVNECATENPCVQ---TCVNTYGSFICRCDPGYELEEDGVH- 244
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C D+DEC+ LC++ C N PG Y C C G+ D RSC
Sbjct: 245 ------CSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSC 286
Score = 126 bits (305), Expect = 2e-28
Identities = 84/263 (31%), Positives = 114/263 (43%), Gaps = 15/263 (5%)
Query: 117 MEVNECAAFPGLC-GHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGD 173
++++EC P C G C N GG+ C P Y N +
Sbjct: 41 LDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLS 100
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHG 232
+ T S CR GY+ D+ S CVD+DECA + C + C+NT G + C C G
Sbjct: 101 APNYPTI-SRPLICRFGYQMDE-SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDG 158
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
L + C DIDEC G C C N G+Y C C+ G+ +
Sbjct: 159 YWLLEGQ--CLDIDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNE-DGRSCQDVNECA 212
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C +CVNT GS+ C C G+ L DG C D+DEC+ C +C N G+Y C
Sbjct: 213 TENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFC 271
Query: 353 TCTDGLVPSAAGAKPTCQDIDEC 375
+C G + +CQDI+EC
Sbjct: 272 SCPPGYI--LLDDNRSCQDINEC 292
Score = 126 bits (305), Expect = 2e-28
Identities = 69/197 (35%), Positives = 94/197 (47%), Gaps = 11/197 (5%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C N GG+TC C GY C+D++EC G C
Sbjct: 126 VDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDIDECRY--GYC-QQL 180
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS++C C PG+ ++ + C D++ECA + + CVNT GSF C C G EL
Sbjct: 181 CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTYGSFICRCDPGYEL 238
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D + C D+DECS + +C + C NQ GTY C C GY
Sbjct: 239 EEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNH 297
Query: 296 RC--QHSCVNTPGSYHC 310
C Q +C N G + C
Sbjct: 298 TCNLQQTCYNLQGGFKC 314
Score = 117 bits (281), Expect = 1e-25
Identities = 59/164 (35%), Positives = 88/164 (53%), Gaps = 11/164 (6%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC G C C N+ G ++C C PG+ + +C DVNEC + C C
Sbjct: 167 LDIDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC-ATENPCVQ-TC 221
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY+ ++ C D+DEC+ ++ LC+ CVN G++ C C G L
Sbjct: 222 VNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQ-HECVNQPGTYFCSCPPGYILL 280
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV----CDEGY 275
D SC+DI+EC + C+ C N G ++C+ C+E Y
Sbjct: 281 DDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPY 324
>AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein.
Length = 448
Score = 148 bits (358), Expect = 6e-35
Identities = 81/210 (38%), Positives = 100/210 (47%), Gaps = 10/210 (4%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GY+ D N CVDV+EC C C NTEG +TC C GY + C+DI
Sbjct: 113 CRFGYQMDESNQ-CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ--CLDI 169
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ C N GS+ C C G L D SC+D++EC+ T C C N
Sbjct: 170 DEC--RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECA-TENPCVQ-TCVNT 224
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
G++ C CD GY H CQH CVN PG+Y C+C G+ L D R
Sbjct: 225 YGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNR 284
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTC 352
SC+DI+EC C Q C N G + C
Sbjct: 285 SCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 140 bits (340), Expect = 9e-33
Identities = 100/333 (30%), Positives = 146/333 (43%), Gaps = 39/333 (11%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRC-ECGHGM 233
C + G+ C G+ D S C+DIDEC CRG CVN G + C + +
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
P + A + +C GY Q +
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGY-QMDESNQCVDVDECATD 134
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C + C+NT G Y C+C +G+ L +G+ C DIDEC G C C N GSY+
Sbjct: 135 SHQCNPTQICINTEGGYTCSCTDGYWL-LEGQ-CLDIDECRYGY--CQQ-LCANVPGSYS 189
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
CTC G + G +CQD++ECA + +P + +C NT
Sbjct: 190 CTCNPGFTLNEDGR--SCQDVNECA----------------TENPCVQ------TCVNTY 225
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGD 469
GSF+C+C GY ++ E G C+D DEC C +C+N PG++ C C G+ D
Sbjct: 226 GSFICRCDPGYELE-EDGVHCSDMDECSFSEFLCQH--ECVNQPGTYFCSCPPGYILLDD 282
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+C+D++EC N C+ + TC N G F+C+
Sbjct: 283 NRSCQDINECEHRNHTCNLQQTCYNLQGGFKCI 315
Score = 136 bits (330), Expect = 1e-31
Identities = 99/327 (30%), Positives = 132/327 (40%), Gaps = 38/327 (11%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTC--HCRPGYKADD 195
G C G++ D ++ C+D++EC + C GD C N G + C P Y+
Sbjct: 21 GNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPY 80
Query: 196 FSKICVDIDECADNDALCRGGRCVNT-AGSFRCECGHGMELAPDRLSCKDIDECSITSGI 254
+ A T + C G+ M+ + C D+DEC+ S
Sbjct: 81 SNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMD---ESNQCVDVDECATDSHQ 137
Query: 255 CS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCR 313
C+ C N G Y C C +GY CQ C N PGSY CTC
Sbjct: 138 CNPTQICINTEGGYTCSCTDGY----WLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCN 193
Query: 314 EGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDID 373
G+ L DGRSC+D++ECA PC C NT GS+ C C G G C D+D
Sbjct: 194 PGFTLNEDGRSCQDVNECA-TENPC-VQTCVNTYGSFICRCDPGYELEEDGVH--CSDMD 249
Query: 374 ECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
EC S E LC C N G++ C CP GY + + +C
Sbjct: 250 EC----------SFSEF----------LC-QHECVNQPGTYFCSCPPGY-ILLDDNRSCQ 287
Query: 434 DDDECELGTCDCHPAADCINLPGSFQC 460
D +ECE C+ C NL G F+C
Sbjct: 288 DINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 133 bits (322), Expect = 1e-30
Identities = 95/289 (32%), Positives = 121/289 (41%), Gaps = 42/289 (14%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+ +PG+ C G+ L C DIDEC C G C N G Y C V
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 360 ---------------PSAAGAKP-TCQDIDECADLISTIIMMSVDELQKSVDPQI----P 399
P A A P + + + + +DE + VD
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDS 135
Query: 400 ELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
C C NT G + C C DGY + Q C D DEC G C C N+PGS+
Sbjct: 136 HQCNPTQICINTEGGYTCSCTDGYWLLEGQ---CLDIDECRYGYCQ----QLCANVPGSY 188
Query: 459 QCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
C C G+ DG +C+DV+EC T N TC NT GSF C CD GY+ + G+
Sbjct: 189 SCTCNPGFTLNEDGRSCQDVNECATENPCVQ---TCVNTYGSFICRCDPGYELEEDGVH- 244
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C D+DEC+ LC++ C N PG Y C C G+ D RSC
Sbjct: 245 ------CSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSC 286
Score = 126 bits (305), Expect = 2e-28
Identities = 84/263 (31%), Positives = 114/263 (43%), Gaps = 15/263 (5%)
Query: 117 MEVNECAAFPGLC-GHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGD 173
++++EC P C G C N GG+ C P Y N +
Sbjct: 41 LDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLS 100
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHG 232
+ T S CR GY+ D+ S CVD+DECA + C + C+NT G + C C G
Sbjct: 101 APNYPTI-SRPLICRFGYQMDE-SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDG 158
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
L + C DIDEC G C C N G+Y C C+ G+ +
Sbjct: 159 YWLLEGQ--CLDIDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNE-DGRSCQDVNECA 212
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C +CVNT GS+ C C G+ L DG C D+DEC+ C +C N G+Y C
Sbjct: 213 TENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFC 271
Query: 353 TCTDGLVPSAAGAKPTCQDIDEC 375
+C G + +CQDI+EC
Sbjct: 272 SCPPGYI--LLDDNRSCQDINEC 292
Score = 126 bits (305), Expect = 2e-28
Identities = 69/197 (35%), Positives = 94/197 (47%), Gaps = 11/197 (5%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C N GG+TC C GY C+D++EC G C
Sbjct: 126 VDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDIDECRY--GYC-QQL 180
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS++C C PG+ ++ + C D++ECA + + CVNT GSF C C G EL
Sbjct: 181 CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTYGSFICRCDPGYEL 238
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D + C D+DECS + +C + C NQ GTY C C GY
Sbjct: 239 EEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNH 297
Query: 296 RC--QHSCVNTPGSYHC 310
C Q +C N G + C
Sbjct: 298 TCNLQQTCYNLQGGFKC 314
Score = 117 bits (281), Expect = 1e-25
Identities = 59/164 (35%), Positives = 88/164 (53%), Gaps = 11/164 (6%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC G C C N+ G ++C C PG+ + +C DVNEC + C C
Sbjct: 167 LDIDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC-ATENPCVQ-TC 221
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY+ ++ C D+DEC+ ++ LC+ CVN G++ C C G L
Sbjct: 222 VNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQ-HECVNQPGTYFCSCPPGYILL 280
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV----CDEGY 275
D SC+DI+EC + C+ C N G ++C+ C+E Y
Sbjct: 281 DDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPY 324
>AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries and
neural crest EGF-like protein protein.
Length = 448
Score = 148 bits (358), Expect = 6e-35
Identities = 81/210 (38%), Positives = 100/210 (47%), Gaps = 10/210 (4%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GY+ D N CVDV+EC C C NTEG +TC C GY + C+DI
Sbjct: 113 CRFGYQMDESNQ-CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ--CLDI 169
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ C N GS+ C C G L D SC+D++EC+ T C C N
Sbjct: 170 DEC--RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECA-TENPCVQ-TCVNT 224
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
G++ C CD GY H CQH CVN PG+Y C+C G+ L D R
Sbjct: 225 YGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNR 284
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTC 352
SC+DI+EC C Q C N G + C
Sbjct: 285 SCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 140 bits (340), Expect = 9e-33
Identities = 100/333 (30%), Positives = 146/333 (43%), Gaps = 39/333 (11%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRC-ECGHGM 233
C + G+ C G+ D S C+DIDEC CRG CVN G + C + +
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
P + A + +C GY Q +
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGY-QMDESNQCVDVDECATD 134
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C + C+NT G Y C+C +G+ L +G+ C DIDEC G C C N GSY+
Sbjct: 135 SHQCNPTQICINTEGGYTCSCTDGYWL-LEGQ-CLDIDECRYGY--CQQ-LCANVPGSYS 189
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
CTC G + G +CQD++ECA + +P + +C NT
Sbjct: 190 CTCNPGFTLNEDGR--SCQDVNECA----------------TENPCVQ------TCVNTY 225
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGD 469
GSF+C+C GY ++ E G C+D DEC C +C+N PG++ C C G+ D
Sbjct: 226 GSFICRCDPGYELE-EDGVHCSDMDECSFSEFLCQH--ECVNQPGTYFCSCPPGYILLDD 282
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+C+D++EC N C+ + TC N G F+C+
Sbjct: 283 NRSCQDINECEHRNHTCNLQQTCYNLQGGFKCI 315
Score = 136 bits (330), Expect = 1e-31
Identities = 99/327 (30%), Positives = 132/327 (40%), Gaps = 38/327 (11%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTC--HCRPGYKADD 195
G C G++ D ++ C+D++EC + C GD C N G + C P Y+
Sbjct: 21 GNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPY 80
Query: 196 FSKICVDIDECADNDALCRGGRCVNT-AGSFRCECGHGMELAPDRLSCKDIDECSITSGI 254
+ A T + C G+ M+ + C D+DEC+ S
Sbjct: 81 SNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMD---ESNQCVDVDECATDSHQ 137
Query: 255 CS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCR 313
C+ C N G Y C C +GY CQ C N PGSY CTC
Sbjct: 138 CNPTQICINTEGGYTCSCTDGY----WLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCN 193
Query: 314 EGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDID 373
G+ L DGRSC+D++ECA PC C NT GS+ C C G G C D+D
Sbjct: 194 PGFTLNEDGRSCQDVNECA-TENPC-VQTCVNTYGSFICRCDPGYELEEDGVH--CSDMD 249
Query: 374 ECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
EC S E LC C N G++ C CP GY + + +C
Sbjct: 250 EC----------SFSEF----------LC-QHECVNQPGTYFCSCPPGY-ILLDDNRSCQ 287
Query: 434 DDDECELGTCDCHPAADCINLPGSFQC 460
D +ECE C+ C NL G F+C
Sbjct: 288 DINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 133 bits (322), Expect = 1e-30
Identities = 95/289 (32%), Positives = 121/289 (41%), Gaps = 42/289 (14%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+ +PG+ C G+ L C DIDEC C G C N G Y C V
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 360 ---------------PSAAGAKP-TCQDIDECADLISTIIMMSVDELQKSVDPQI----P 399
P A A P + + + + +DE + VD
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDS 135
Query: 400 ELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
C C NT G + C C DGY + Q C D DEC G C C N+PGS+
Sbjct: 136 HQCNPTQICINTEGGYTCSCTDGYWLLEGQ---CLDIDECRYGYCQ----QLCANVPGSY 188
Query: 459 QCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
C C G+ DG +C+DV+EC T N TC NT GSF C CD GY+ + G+
Sbjct: 189 SCTCNPGFTLNEDGRSCQDVNECATENPCVQ---TCVNTYGSFICRCDPGYELEEDGVH- 244
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C D+DEC+ LC++ C N PG Y C C G+ D RSC
Sbjct: 245 ------CSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSC 286
Score = 126 bits (305), Expect = 2e-28
Identities = 84/263 (31%), Positives = 114/263 (43%), Gaps = 15/263 (5%)
Query: 117 MEVNECAAFPGLC-GHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGD 173
++++EC P C G C N GG+ C P Y N +
Sbjct: 41 LDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLS 100
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHG 232
+ T S CR GY+ D+ S CVD+DECA + C + C+NT G + C C G
Sbjct: 101 APNYPTI-SRPLICRFGYQMDE-SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDG 158
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
L + C DIDEC G C C N G+Y C C+ G+ +
Sbjct: 159 YWLLEGQ--CLDIDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNE-DGRSCQDVNECA 212
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C +CVNT GS+ C C G+ L DG C D+DEC+ C +C N G+Y C
Sbjct: 213 TENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFC 271
Query: 353 TCTDGLVPSAAGAKPTCQDIDEC 375
+C G + +CQDI+EC
Sbjct: 272 SCPPGYI--LLDDNRSCQDINEC 292
Score = 126 bits (305), Expect = 2e-28
Identities = 69/197 (35%), Positives = 94/197 (47%), Gaps = 11/197 (5%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C N GG+TC C GY C+D++EC G C
Sbjct: 126 VDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDIDECRY--GYC-QQL 180
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS++C C PG+ ++ + C D++ECA + + CVNT GSF C C G EL
Sbjct: 181 CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTYGSFICRCDPGYEL 238
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D + C D+DECS + +C + C NQ GTY C C GY
Sbjct: 239 EEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNH 297
Query: 296 RC--QHSCVNTPGSYHC 310
C Q +C N G + C
Sbjct: 298 TCNLQQTCYNLQGGFKC 314
Score = 117 bits (281), Expect = 1e-25
Identities = 59/164 (35%), Positives = 88/164 (53%), Gaps = 11/164 (6%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC G C C N+ G ++C C PG+ + +C DVNEC + C C
Sbjct: 167 LDIDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC-ATENPCVQ-TC 221
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY+ ++ C D+DEC+ ++ LC+ CVN G++ C C G L
Sbjct: 222 VNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQ-HECVNQPGTYFCSCPPGYILL 280
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV----CDEGY 275
D SC+DI+EC + C+ C N G ++C+ C+E Y
Sbjct: 281 DDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPY 324
>AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein.
Length = 448
Score = 146 bits (354), Expect = 2e-34
Identities = 81/210 (38%), Positives = 99/210 (47%), Gaps = 10/210 (4%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GY+ D N CVDV+EC C C NTEG +TC C GY + C+DI
Sbjct: 113 CRFGYQMDESNQ-CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ--CLDI 169
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ C N GS+ C C G L D SC+D++EC+ T C C N
Sbjct: 170 DEC--RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECA-TENPCVQ-TCVNT 224
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
G+ C CD GY H CQH CVN PG+Y C+C G+ L D R
Sbjct: 225 YGSLICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNR 284
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTC 352
SC+DI+EC C Q C N G + C
Sbjct: 285 SCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 138 bits (334), Expect = 5e-32
Identities = 99/333 (29%), Positives = 145/333 (43%), Gaps = 39/333 (11%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRC-ECGHGM 233
C + G+ C G+ D S C+DIDEC CRG CVN G + C + +
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
P + A + +C GY Q +
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGY-QMDESNQCVDVDECATD 134
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C + C+NT G Y C+C +G+ L +G+ C DIDEC G C C N GSY+
Sbjct: 135 SHQCNPTQICINTEGGYTCSCTDGYWL-LEGQ-CLDIDECRYGY--CQQ-LCANVPGSYS 189
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
CTC G + G +CQD++ECA + +P + +C NT
Sbjct: 190 CTCNPGFTLNEDGR--SCQDVNECA----------------TENPCVQ------TCVNTY 225
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGD 469
GS +C+C GY ++ E G C+D DEC C +C+N PG++ C C G+ D
Sbjct: 226 GSLICRCDPGYELE-EDGVHCSDMDECSFSEFLCQH--ECVNQPGTYFCSCPPGYILLDD 282
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+C+D++EC N C+ + TC N G F+C+
Sbjct: 283 NRSCQDINECEHRNHTCNLQQTCYNLQGGFKCI 315
Score = 135 bits (326), Expect = 5e-31
Identities = 99/327 (30%), Positives = 131/327 (40%), Gaps = 38/327 (11%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTC--HCRPGYKADD 195
G C G++ D ++ C+D++EC + C GD C N G + C P Y+
Sbjct: 21 GNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPY 80
Query: 196 FSKICVDIDECADNDALCRGGRCVNT-AGSFRCECGHGMELAPDRLSCKDIDECSITSGI 254
+ A T + C G+ M+ + C D+DEC+ S
Sbjct: 81 SNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMD---ESNQCVDVDECATDSHQ 137
Query: 255 CS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCR 313
C+ C N G Y C C +GY CQ C N PGSY CTC
Sbjct: 138 CNPTQICINTEGGYTCSCTDGY----WLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCN 193
Query: 314 EGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDID 373
G+ L DGRSC+D++ECA PC C NT GS C C G G C D+D
Sbjct: 194 PGFTLNEDGRSCQDVNECA-TENPC-VQTCVNTYGSLICRCDPGYELEEDGVH--CSDMD 249
Query: 374 ECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
EC S E LC C N G++ C CP GY + + +C
Sbjct: 250 EC----------SFSEF----------LC-QHECVNQPGTYFCSCPPGY-ILLDDNRSCQ 287
Query: 434 DDDECELGTCDCHPAADCINLPGSFQC 460
D +ECE C+ C NL G F+C
Sbjct: 288 DINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 131 bits (316), Expect = 7e-30
Identities = 94/289 (32%), Positives = 120/289 (41%), Gaps = 42/289 (14%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+ +PG+ C G+ L C DIDEC C G C N G Y C V
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 360 ---------------PSAAGAKP-TCQDIDECADLISTIIMMSVDELQKSVDPQI----P 399
P A A P + + + + +DE + VD
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDS 135
Query: 400 ELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
C C NT G + C C DGY + Q C D DEC G C C N+PGS+
Sbjct: 136 HQCNPTQICINTEGGYTCSCTDGYWLLEGQ---CLDIDECRYGYCQ----QLCANVPGSY 188
Query: 459 QCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
C C G+ DG +C+DV+EC T N TC NT GS C CD GY+ + G+
Sbjct: 189 SCTCNPGFTLNEDGRSCQDVNECATENPCVQ---TCVNTYGSLICRCDPGYELEEDGVH- 244
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C D+DEC+ LC++ C N PG Y C C G+ D RSC
Sbjct: 245 ------CSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSC 286
Score = 125 bits (301), Expect = 5e-28
Identities = 84/263 (31%), Positives = 113/263 (42%), Gaps = 15/263 (5%)
Query: 117 MEVNECAAFPGLC-GHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGD 173
++++EC P C G C N GG+ C P Y N +
Sbjct: 41 LDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLS 100
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHG 232
+ T S CR GY+ D+ S CVD+DECA + C + C+NT G + C C G
Sbjct: 101 APNYPTI-SRPLICRFGYQMDE-SNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDG 158
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
L + C DIDEC G C C N G+Y C C+ G+ +
Sbjct: 159 YWLLEGQ--CLDIDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNE-DGRSCQDVNECA 212
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C +CVNT GS C C G+ L DG C D+DEC+ C +C N G+Y C
Sbjct: 213 TENPCVQTCVNTYGSLICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFC 271
Query: 353 TCTDGLVPSAAGAKPTCQDIDEC 375
+C G + +CQDI+EC
Sbjct: 272 SCPPGYI--LLDDNRSCQDINEC 292
Score = 124 bits (299), Expect = 8e-28
Identities = 68/197 (34%), Positives = 93/197 (47%), Gaps = 11/197 (5%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C N GG+TC C GY C+D++EC G C
Sbjct: 126 VDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDIDECRY--GYC-QQL 180
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS++C C PG+ ++ + C D++ECA + + CVNT GS C C G EL
Sbjct: 181 CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTYGSLICRCDPGYEL 238
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D + C D+DECS + +C + C NQ GTY C C GY
Sbjct: 239 EEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNH 297
Query: 296 RC--QHSCVNTPGSYHC 310
C Q +C N G + C
Sbjct: 298 TCNLQQTCYNLQGGFKC 314
Score = 114 bits (275), Expect = 7e-25
Identities = 58/164 (35%), Positives = 87/164 (53%), Gaps = 11/164 (6%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC G C C N+ G ++C C PG+ + +C DVNEC + C C
Sbjct: 167 LDIDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC-ATENPCVQ-TC 221
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS C C PGY+ ++ C D+DEC+ ++ LC+ CVN G++ C C G L
Sbjct: 222 VNTYGSLICRCDPGYELEEDGVHCSDMDECSFSEFLCQ-HECVNQPGTYFCSCPPGYILL 280
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV----CDEGY 275
D SC+DI+EC + C+ C N G ++C+ C+E Y
Sbjct: 281 DDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPY 324
>AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein
protein.
Length = 511
Score = 146 bits (354), Expect = 2e-34
Identities = 106/354 (29%), Positives = 142/354 (40%), Gaps = 50/354 (14%)
Query: 128 LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
+C +G C N G F C C GY C D++EC+ C GDC NT GS+ C C
Sbjct: 2 VCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDF-PAACIGGDCINTNGSYRCLC 60
Query: 188 RPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
G++ K C DIDEC+ + +LC G C N GS+ C C G D+ C++++
Sbjct: 61 PQGHRLVGGRK-CQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVE 119
Query: 247 ECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ-HSC-VNT 304
+ + E + V + + V C+ + C V +
Sbjct: 120 Q--------PHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYS 171
Query: 305 PGSYHCTCREGWHLRADGR-------SCRDIDEC-AGGARPCGGGQCRNTVGSYTCTCTD 356
+H C +G D + RDIDEC G+ C G+C NT Y C C
Sbjct: 172 SAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQ 231
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G G C D+DEC D C G C NT G + C
Sbjct: 232 GFYYD--GNLLECVDVDECLD---------------------ESNCRNGVCENTRGGYRC 268
Query: 417 QC--PDGYSVKPEQ--GPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C P YS Q P D DEC+ C P C+NLPGS++C CR W
Sbjct: 269 ACTPPAEYSPAQRQCLSPEEMDVDECQ-DPAACRPGR-CVNLPGSYRCECRPPW 320
Score = 120 bits (289), Expect = 1e-26
Identities = 134/506 (26%), Positives = 183/506 (36%), Gaps = 90/506 (17%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDC 176
+++EC FP C G C N G + C C G+ C D++EC +C G C
Sbjct: 34 DIDECD-FPAACIGGDCINTNGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPHGAC 91
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDID------ECA---DNDALCRGGRCVNTAGSFRC 227
N +GS+ C C G+ C +++ EC D+ C N C
Sbjct: 92 KNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQ-EC 150
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXX 287
C G C +I C + S + C + G Q D + +H
Sbjct: 151 CCSLGAGWGDH---C-EIYPCPVYSSAEFHSLCPDGKGYTQ---DNNIVNYGIPAHRDID 203
Query: 288 XXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNT 346
C+ CVNT Y C C++G++ + C D+DEC + C G C NT
Sbjct: 204 ECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESN-CRNGVCENT 262
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
G Y C CT S A + C +E M VDE Q P C G
Sbjct: 263 RGGYRCACTPPAEYSPAQRQ--CLSPEE----------MDVDECQD------PAACRPGR 304
Query: 407 CHNTIGSFVCQC-------PDGYSVKPEQGP---ACTDDDEC-----ELGTCDCHPAADC 451
C N GS+ C+C P G + + P A D C E G C A
Sbjct: 305 CVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPA 364
Query: 452 INLPGSFQCRCRDGWRGDGATCEDV------DECLTNNG-------------GCHPRATC 492
+ C CR G RG GA C C T+ G PR
Sbjct: 365 LTFD---DCCCRQG-RGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDED 420
Query: 493 ANTDGSFRCLCDTGY---KGDGY------GLRTVCCVYSCVDIDECA---NDPTLCENGH 540
++ + S C C +G + G G + CVDIDEC LC++
Sbjct: 421 SSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSER 480
Query: 541 CSNTPGGYECDCDVGFTRAADGRSCL 566
C NT G + C C GF R+ +C+
Sbjct: 481 CVNTSGSFRCVCKAGFARSRPHGACV 506
Score = 99 bits (238), Expect = 2e-20
Identities = 53/118 (44%), Positives = 65/118 (55%), Gaps = 13/118 (11%)
Query: 451 CINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
C N PGSFQC+C G+ D + CED+DEC C C NT+GS+RCLC G++
Sbjct: 8 CSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIG-GDCINTNGSYRCLCPQGHR 65
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G G + C DIDEC+ DP+LC +G C N G Y C CD GFT D C
Sbjct: 66 LVG-GRK-------CQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGC 115
Score = 98.3 bits (234), Expect = 6e-20
Identities = 55/159 (34%), Positives = 77/159 (48%), Gaps = 7/159 (4%)
Query: 400 ELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQ 459
++C G C NT GSF CQC GY + ++ C D DEC+ C DCIN GS++
Sbjct: 1 DVCDNGICSNTPGSFQCQCLSGYHLSRDRSH-CEDIDECDFPAA-CI-GGDCINTNGSYR 57
Query: 460 CRCRDGWR-GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY--KGDGYGLRT 516
C C G R G C+D+DEC + C P C N GS+ C+CD G+ D +G
Sbjct: 58 CLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEE 117
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
V + + +D C++ +N EC C +G
Sbjct: 118 VEQPHHKKECYLNFDDTVFCDSVLATNVT-QQECCCSLG 155
Score = 42.3 bits (95), Expect = 0.004
Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAY 44
G C+GPL L CC G+ WG Q C PCP +G ++
Sbjct: 354 GMCAGPLAGPALTFDDCCCRQGRGWGAQ-CRPCPPRGAGSH 393
Score = 40.7 bits (91), Expect = 0.013
Identities = 14/31 (45%), Positives = 20/31 (64%)
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+C+NG CSNTPG ++C C G+ + D C
Sbjct: 2 VCDNGICSNTPGSFQCQCLSGYHLSRDRSHC 32
Score = 39.5 bits (88), Expect = 0.031
Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 4/45 (8%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQRCE--PCPKKGTDAYQNLC 48
C L T+V + CCCS LG WG+ CE PCP + + +LC
Sbjct: 137 CDSVLATNVTQQECCCS-LGAGWGD-HCEIYPCPVYSSAEFHSLC 179
>U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein
protein.
Length = 387
Score = 146 bits (353), Expect = 2e-34
Identities = 94/279 (33%), Positives = 134/279 (48%), Gaps = 20/279 (7%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GYE+ S+++ C D++EC C D C N GSF C C PGY+ + CVDI
Sbjct: 53 CAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDI 109
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C RCVNT GSF C+C G +LA + +C DI+EC S C+ C N
Sbjct: 110 DECTI-PPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDINECD-ASNQCAQ-QCYNI 165
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
+G++ C C++GY S+ + + CQ+ CVN PG + C C +G+ + R
Sbjct: 166 LGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQV-VRSR 224
Query: 324 SCRDIDECAGGARPCGGGQCRNTVGSYTC----TCTDG--LVPSAAGAKPTCQDIDECAD 377
+C+DI+EC C N G + C C D L P P + C +
Sbjct: 225 TCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CRE 282
Query: 378 LISTII--MMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
L +I+ MS+ +SV I ++ NTI +F
Sbjct: 283 LPQSIVYKYMSI-RSDRSVPSDIFQIQATTIYANTINTF 320
Score = 139 bits (336), Expect = 3e-32
Identities = 75/196 (38%), Positives = 101/196 (51%), Gaps = 12/196 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++EC A C + C NL G F C C PGY+K + CVD++EC I C C
Sbjct: 67 DIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPP-YCHQR-C 122
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PG++ + CVDI+EC D C +C N GSF C+C G EL+
Sbjct: 123 VNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC-AQQCYNILGSFICQCNQGYELS 180
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
DRL+C+DIDEC +S +C C N+ G + C+C +GY V+S
Sbjct: 181 SDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGY--QVVRSRTCQDINECETTNE 237
Query: 297 CQHS--CVNTPGSYHC 310
C+ C N G + C
Sbjct: 238 CREDEMCWNYHGGFRC 253
Score = 118 bits (283), Expect = 7e-26
Identities = 82/247 (33%), Positives = 107/247 (43%), Gaps = 44/247 (17%)
Query: 307 SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGA 365
S+ C G+ +++ C+DIDEC G C Q C N GS+ C C G G
Sbjct: 48 SHRIQCAAGYE-QSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGY--QKRGE 104
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVK 425
+ C DIDEC IP C C NT GSF CQC G+ +
Sbjct: 105 Q--CVDIDECT---------------------IPPYCHQ-RCVNTPGSFYCQCSPGFQLA 140
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNN 483
C D +EC+ C A C N+ GSF C+C G+ D CED+DEC T++
Sbjct: 141 ANNY-TCVDINECDASN-QC--AQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSS 196
Query: 484 GGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSN 543
C + C N G F C+C GY+ V +C DI+EC E+ C N
Sbjct: 197 YLCQYQ--CVNEPGKFSCMCPQGYQ--------VVRSRTCQDINECETTNECREDEMCWN 246
Query: 544 TPGGYEC 550
GG+ C
Sbjct: 247 YHGGFRC 253
Score = 116 bits (278), Expect = 3e-25
Identities = 77/242 (31%), Positives = 106/242 (43%), Gaps = 33/242 (13%)
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKS 282
S R +C G E + + C+DIDEC+ + C ++ C N G++ C C GY + +
Sbjct: 48 SHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK---RG 103
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ 342
C CVNTPGS++C C G+ L A+ +C DI+EC + C Q
Sbjct: 104 EQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC-AQQ 161
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
C N +GS+ C C G + + C+DIDEC LC
Sbjct: 162 CYNILGSFICQCNQGY--ELSSDRLNCEDIDECR--------------------TSSYLC 199
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
C N G F C CP GY V + C D +ECE T +C C N G F+C
Sbjct: 200 -QYQCVNEPGKFSCMCPQGYQV--VRSRTCQDINECET-TNECREDEMCWNYHGGFRCYP 255
Query: 463 RD 464
R+
Sbjct: 256 RN 257
Score = 107 bits (257), Expect = 1e-22
Identities = 63/161 (39%), Positives = 82/161 (50%), Gaps = 20/161 (12%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N GSF CQCP GY + EQ C D DEC + CH C+N PGSF C+C G+
Sbjct: 84 CINLRGSFACQCPPGYQKRGEQ---CVDIDECTIPPY-CHQR--CVNTPGSFYCQCSPGF 137
Query: 467 R--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ + TC D++EC +N C + C N GSF C C+ GY+ L +C
Sbjct: 138 QLAANNYTCVDINECDASN-QCAQQ--CYNILGSFICQCNQGYELSSDRL-------NCE 187
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DIDEC LC+ C N PG + C C G+ + R+C
Sbjct: 188 DIDECRTSSYLCQY-QCVNEPGKFSCMCPQGY-QVVRSRTC 226
Score = 103 bits (246), Expect = 2e-21
Identities = 57/149 (38%), Positives = 75/149 (50%), Gaps = 14/149 (9%)
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
QC GY + + C D DEC GT +C CINL GSF C+C G++ G C D+
Sbjct: 52 QCAAGY--EQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDI 109
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC T CH R C NT GSF C C G+ + Y+CVDI+EC + C
Sbjct: 110 DEC-TIPPYCHQR--CVNTPGSFYCQCSPGF-------QLAANNYTCVDINEC-DASNQC 158
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C N G + C C+ G+ ++D +C
Sbjct: 159 AQ-QCYNILGSFICQCNQGYELSSDRLNC 186
Score = 77.4 bits (182), Expect = 1e-13
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 12/111 (10%)
Query: 457 SFQCRCRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
S + +C G+ + + C+D+DEC C C N GSF C C GY+ G
Sbjct: 48 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE--- 104
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CVDIDEC P C C NTPG + C C GF AA+ +C+
Sbjct: 105 ------QCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCV 147
>BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 146 bits (353), Expect = 2e-34
Identities = 94/279 (33%), Positives = 134/279 (48%), Gaps = 20/279 (7%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GYE+ S+++ C D++EC C D C N GSF C C PGY+ + CVDI
Sbjct: 159 CAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDI 215
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C RCVNT GSF C+C G +LA + +C DI+EC S C+ C N
Sbjct: 216 DECTI-PPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDINECD-ASNQCAQ-QCYNI 271
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
+G++ C C++GY S+ + + CQ+ CVN PG + C C +G+ + R
Sbjct: 272 LGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQV-VRSR 330
Query: 324 SCRDIDECAGGARPCGGGQCRNTVGSYTC----TCTDG--LVPSAAGAKPTCQDIDECAD 377
+C+DI+EC C N G + C C D L P P + C +
Sbjct: 331 TCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CRE 388
Query: 378 LISTII--MMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
L +I+ MS+ +SV I ++ NTI +F
Sbjct: 389 LPQSIVYKYMSI-RSDRSVPSDIFQIQATTIYANTINTF 426
Score = 141 bits (341), Expect = 7e-33
Identities = 113/382 (29%), Positives = 153/382 (40%), Gaps = 50/382 (13%)
Query: 178 NTEGSFT-CHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRCECGHGMEL 235
+TE + T C GY+ D + C DIDEC C+GG +CVN G + C +
Sbjct: 19 DTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQII 78
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQST--VKSHXXXXXXXXXX 293
+ ++ TSG + + M T + G+ S V
Sbjct: 79 VNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFV 138
Query: 294 XXRCQHSCVNTPG--SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSY 350
R P S+ C G+ +++ C+DIDEC G C Q C N GS+
Sbjct: 139 IRRNPADPQRIPSNPSHRIQCAAGYE-QSEHNVCQDIDECTAGTHNCRADQVCINLRGSF 197
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNT 410
C C G G + C DIDEC IP C C NT
Sbjct: 198 ACQCPPGY--QKRGEQ--CVDIDECT---------------------IPPYCHQ-RCVNT 231
Query: 411 IGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--G 468
GSF CQC G+ + C D +EC+ C A C N+ GSF C+C G+
Sbjct: 232 PGSFYCQCSPGFQLAANNY-TCVDINECDASN-QC--AQQCYNILGSFICQCNQGYELSS 287
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
D CED+DEC T++ C + C N G F C+C GY+ V +C DI+E
Sbjct: 288 DRLNCEDIDECRTSSYLCQYQ--CVNEPGKFSCMCPQGYQ--------VVRSRTCQDINE 337
Query: 529 CANDPTLCENGHCSNTPGGYEC 550
C E+ C N GG+ C
Sbjct: 338 CETTNECREDEMCWNYHGGFRC 359
Score = 139 bits (336), Expect = 3e-32
Identities = 75/196 (38%), Positives = 101/196 (51%), Gaps = 12/196 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++EC A C + C NL G F C C PGY+K + CVD++EC I C C
Sbjct: 173 DIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPP-YCHQR-C 228
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PG++ + CVDI+EC D C +C N GSF C+C G EL+
Sbjct: 229 VNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC-AQQCYNILGSFICQCNQGYELS 286
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
DRL+C+DIDEC +S +C C N+ G + C+C +GY V+S
Sbjct: 287 SDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGY--QVVRSRTCQDINECETTNE 343
Query: 297 CQHS--CVNTPGSYHC 310
C+ C N G + C
Sbjct: 344 CREDEMCWNYHGGFRC 359
Score = 127 bits (307), Expect = 9e-29
Identities = 100/363 (27%), Positives = 141/363 (38%), Gaps = 38/363 (10%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GYE D C D++EC+IV C G C N G + C + + + +
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET 88
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
G ++ + G G + ++ ++ I N A +
Sbjct: 89 QPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQR 148
Query: 264 M---GTYQCVCDEGYAQSTVK-SHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
+ +++ C GY QS R C+N GS+ C C G+ R
Sbjct: 149 IPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR 208
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
G C DIDEC P +C NT GS+ C C+ G A TC DI+EC
Sbjct: 209 --GEQCVDIDECT--IPPYCHQRCVNTPGSFYCQCSPGF--QLAANNYTCVDINEC---- 258
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE 439
C A C+N +GSF+CQC GY + ++ C D DEC
Sbjct: 259 -----------------DASNQC-AQQCYNILGSFICQCNQGYELSSDR-LNCEDIDECR 299
Query: 440 LGTCDCHPAADCINLPGSFQCRCRDGWR-GDGATCEDVDECLTNNGGCHPRATCANTDGS 498
+ C C+N PG F C C G++ TC+D++EC T N C C N G
Sbjct: 300 TSSYLCQ--YQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTN-ECREDEMCWNYHGG 356
Query: 499 FRC 501
FRC
Sbjct: 357 FRC 359
Score = 116 bits (278), Expect = 3e-25
Identities = 77/242 (31%), Positives = 106/242 (43%), Gaps = 33/242 (13%)
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKS 282
S R +C G E + + C+DIDEC+ + C ++ C N G++ C C GY + +
Sbjct: 154 SHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK---RG 209
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ 342
C CVNTPGS++C C G+ L A+ +C DI+EC + C Q
Sbjct: 210 EQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC-AQQ 267
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
C N +GS+ C C G + + C+DIDEC LC
Sbjct: 268 CYNILGSFICQCNQGY--ELSSDRLNCEDIDECR--------------------TSSYLC 305
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
C N G F C CP GY V + C D +ECE T +C C N G F+C
Sbjct: 306 -QYQCVNEPGKFSCMCPQGYQV--VRSRTCQDINECET-TNECREDEMCWNYHGGFRCYP 361
Query: 463 RD 464
R+
Sbjct: 362 RN 363
Score = 107 bits (257), Expect = 1e-22
Identities = 63/161 (39%), Positives = 82/161 (50%), Gaps = 20/161 (12%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N GSF CQCP GY + EQ C D DEC + CH C+N PGSF C+C G+
Sbjct: 190 CINLRGSFACQCPPGYQKRGEQ---CVDIDECTIPPY-CHQR--CVNTPGSFYCQCSPGF 243
Query: 467 R--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ + TC D++EC +N C + C N GSF C C+ GY+ L +C
Sbjct: 244 QLAANNYTCVDINECDASN-QCAQQ--CYNILGSFICQCNQGYELSSDRL-------NCE 293
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DIDEC LC+ C N PG + C C G+ + R+C
Sbjct: 294 DIDECRTSSYLCQY-QCVNEPGKFSCMCPQGY-QVVRSRTC 332
Score = 103 bits (246), Expect = 2e-21
Identities = 57/149 (38%), Positives = 75/149 (50%), Gaps = 14/149 (9%)
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
QC GY + + C D DEC GT +C CINL GSF C+C G++ G C D+
Sbjct: 158 QCAAGY--EQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDI 215
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC T CH R C NT GSF C C G+ + Y+CVDI+EC + C
Sbjct: 216 DEC-TIPPYCHQR--CVNTPGSFYCQCSPGF-------QLAANNYTCVDINEC-DASNQC 264
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C N G + C C+ G+ ++D +C
Sbjct: 265 AQ-QCYNILGSFICQCNQGYELSSDRLNC 292
Score = 77.4 bits (182), Expect = 1e-13
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 12/111 (10%)
Query: 457 SFQCRCRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
S + +C G+ + + C+D+DEC C C N GSF C C GY+ G
Sbjct: 154 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE--- 210
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CVDIDEC P C C NTPG + C C GF AA+ +C+
Sbjct: 211 ------QCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCV 253
>BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 146 bits (353), Expect = 2e-34
Identities = 94/279 (33%), Positives = 134/279 (48%), Gaps = 20/279 (7%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GYE+ S+++ C D++EC C D C N GSF C C PGY+ + CVDI
Sbjct: 159 CAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDI 215
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C RCVNT GSF C+C G +LA + +C DI+EC S C+ C N
Sbjct: 216 DECTI-PPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDINECD-ASNQCAQ-QCYNI 271
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
+G++ C C++GY S+ + + CQ+ CVN PG + C C +G+ + R
Sbjct: 272 LGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQV-VRSR 330
Query: 324 SCRDIDECAGGARPCGGGQCRNTVGSYTC----TCTDG--LVPSAAGAKPTCQDIDECAD 377
+C+DI+EC C N G + C C D L P P + C +
Sbjct: 331 TCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CRE 388
Query: 378 LISTII--MMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
L +I+ MS+ +SV I ++ NTI +F
Sbjct: 389 LPQSIVYKYMSI-RSDRSVPSDIFQIQATTIYANTINTF 426
Score = 141 bits (341), Expect = 7e-33
Identities = 113/382 (29%), Positives = 153/382 (40%), Gaps = 50/382 (13%)
Query: 178 NTEGSFT-CHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRCECGHGMEL 235
+TE + T C GY+ D + C DIDEC C+GG +CVN G + C +
Sbjct: 19 DTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQII 78
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQST--VKSHXXXXXXXXXX 293
+ ++ TSG + + M T + G+ S V
Sbjct: 79 VNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFV 138
Query: 294 XXRCQHSCVNTPG--SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSY 350
R P S+ C G+ +++ C+DIDEC G C Q C N GS+
Sbjct: 139 IRRNPADPQRIPSNPSHRIQCAAGYE-QSEHNVCQDIDECTAGTHNCRADQVCINLRGSF 197
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNT 410
C C G G + C DIDEC IP C C NT
Sbjct: 198 ACQCPPGY--QKRGEQ--CVDIDECT---------------------IPPYCHQ-RCVNT 231
Query: 411 IGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--G 468
GSF CQC G+ + C D +EC+ C A C N+ GSF C+C G+
Sbjct: 232 PGSFYCQCSPGFQLAANNY-TCVDINECDASN-QC--AQQCYNILGSFICQCNQGYELSS 287
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
D CED+DEC T++ C + C N G F C+C GY+ V +C DI+E
Sbjct: 288 DRLNCEDIDECRTSSYLCQYQ--CVNEPGKFSCMCPQGYQ--------VVRSRTCQDINE 337
Query: 529 CANDPTLCENGHCSNTPGGYEC 550
C E+ C N GG+ C
Sbjct: 338 CETTNECREDEMCWNYHGGFRC 359
Score = 139 bits (336), Expect = 3e-32
Identities = 75/196 (38%), Positives = 101/196 (51%), Gaps = 12/196 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++EC A C + C NL G F C C PGY+K + CVD++EC I C C
Sbjct: 173 DIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPP-YCHQR-C 228
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PG++ + CVDI+EC D C +C N GSF C+C G EL+
Sbjct: 229 VNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC-AQQCYNILGSFICQCNQGYELS 286
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
DRL+C+DIDEC +S +C C N+ G + C+C +GY V+S
Sbjct: 287 SDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGY--QVVRSRTCQDINECETTNE 343
Query: 297 CQHS--CVNTPGSYHC 310
C+ C N G + C
Sbjct: 344 CREDEMCWNYHGGFRC 359
Score = 127 bits (307), Expect = 9e-29
Identities = 100/363 (27%), Positives = 141/363 (38%), Gaps = 38/363 (10%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GYE D C D++EC+IV C G C N G + C + + + +
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET 88
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
G ++ + G G + ++ ++ I N A +
Sbjct: 89 QPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQR 148
Query: 264 M---GTYQCVCDEGYAQSTVK-SHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
+ +++ C GY QS R C+N GS+ C C G+ R
Sbjct: 149 IPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR 208
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
G C DIDEC P +C NT GS+ C C+ G A TC DI+EC
Sbjct: 209 --GEQCVDIDECT--IPPYCHQRCVNTPGSFYCQCSPGF--QLAANNYTCVDINEC---- 258
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE 439
C A C+N +GSF+CQC GY + ++ C D DEC
Sbjct: 259 -----------------DASNQC-AQQCYNILGSFICQCNQGYELSSDR-LNCEDIDECR 299
Query: 440 LGTCDCHPAADCINLPGSFQCRCRDGWR-GDGATCEDVDECLTNNGGCHPRATCANTDGS 498
+ C C+N PG F C C G++ TC+D++EC T N C C N G
Sbjct: 300 TSSYLCQ--YQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTN-ECREDEMCWNYHGG 356
Query: 499 FRC 501
FRC
Sbjct: 357 FRC 359
Score = 116 bits (278), Expect = 3e-25
Identities = 77/242 (31%), Positives = 106/242 (43%), Gaps = 33/242 (13%)
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKS 282
S R +C G E + + C+DIDEC+ + C ++ C N G++ C C GY + +
Sbjct: 154 SHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK---RG 209
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ 342
C CVNTPGS++C C G+ L A+ +C DI+EC + C Q
Sbjct: 210 EQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC-AQQ 267
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
C N +GS+ C C G + + C+DIDEC LC
Sbjct: 268 CYNILGSFICQCNQGY--ELSSDRLNCEDIDECR--------------------TSSYLC 305
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
C N G F C CP GY V + C D +ECE T +C C N G F+C
Sbjct: 306 -QYQCVNEPGKFSCMCPQGYQV--VRSRTCQDINECET-TNECREDEMCWNYHGGFRCYP 361
Query: 463 RD 464
R+
Sbjct: 362 RN 363
Score = 107 bits (257), Expect = 1e-22
Identities = 63/161 (39%), Positives = 82/161 (50%), Gaps = 20/161 (12%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N GSF CQCP GY + EQ C D DEC + CH C+N PGSF C+C G+
Sbjct: 190 CINLRGSFACQCPPGYQKRGEQ---CVDIDECTIPPY-CHQR--CVNTPGSFYCQCSPGF 243
Query: 467 R--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ + TC D++EC +N C + C N GSF C C+ GY+ L +C
Sbjct: 244 QLAANNYTCVDINECDASN-QCAQQ--CYNILGSFICQCNQGYELSSDRL-------NCE 293
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DIDEC LC+ C N PG + C C G+ + R+C
Sbjct: 294 DIDECRTSSYLCQY-QCVNEPGKFSCMCPQGY-QVVRSRTC 332
Score = 103 bits (246), Expect = 2e-21
Identities = 57/149 (38%), Positives = 75/149 (50%), Gaps = 14/149 (9%)
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
QC GY + + C D DEC GT +C CINL GSF C+C G++ G C D+
Sbjct: 158 QCAAGY--EQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDI 215
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC T CH R C NT GSF C C G+ + Y+CVDI+EC + C
Sbjct: 216 DEC-TIPPYCHQR--CVNTPGSFYCQCSPGF-------QLAANNYTCVDINEC-DASNQC 264
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C N G + C C+ G+ ++D +C
Sbjct: 265 AQ-QCYNILGSFICQCNQGYELSSDRLNC 292
Score = 77.4 bits (182), Expect = 1e-13
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 12/111 (10%)
Query: 457 SFQCRCRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
S + +C G+ + + C+D+DEC C C N GSF C C GY+ G
Sbjct: 154 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE--- 210
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CVDIDEC P C C NTPG + C C GF AA+ +C+
Sbjct: 211 ------QCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCV 253
>AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 146 bits (353), Expect = 2e-34
Identities = 94/279 (33%), Positives = 134/279 (48%), Gaps = 20/279 (7%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GYE+ S+++ C D++EC C D C N GSF C C PGY+ + CVDI
Sbjct: 159 CAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDI 215
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C RCVNT GSF C+C G +LA + +C DI+EC S C+ C N
Sbjct: 216 DECTI-PPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDINECD-ASNQCAQ-QCYNI 271
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
+G++ C C++GY S+ + + CQ+ CVN PG + C C +G+ + R
Sbjct: 272 LGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQV-VRSR 330
Query: 324 SCRDIDECAGGARPCGGGQCRNTVGSYTC----TCTDG--LVPSAAGAKPTCQDIDECAD 377
+C+DI+EC C N G + C C D L P P + C +
Sbjct: 331 TCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CRE 388
Query: 378 LISTII--MMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
L +I+ MS+ +SV I ++ NTI +F
Sbjct: 389 LPQSIVYKYMSI-RSDRSVPSDIFQIQATTIYANTINTF 426
Score = 141 bits (341), Expect = 7e-33
Identities = 113/382 (29%), Positives = 153/382 (40%), Gaps = 50/382 (13%)
Query: 178 NTEGSFT-CHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRCECGHGMEL 235
+TE + T C GY+ D + C DIDEC C+GG +CVN G + C +
Sbjct: 19 DTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQII 78
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQST--VKSHXXXXXXXXXX 293
+ ++ TSG + + M T + G+ S V
Sbjct: 79 VNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFV 138
Query: 294 XXRCQHSCVNTPG--SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSY 350
R P S+ C G+ +++ C+DIDEC G C Q C N GS+
Sbjct: 139 IRRNPADPQRIPSNPSHRIQCAAGYE-QSEHNVCQDIDECTAGTHNCRADQVCINLRGSF 197
Query: 351 TCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNT 410
C C G G + C DIDEC IP C C NT
Sbjct: 198 ACQCPPGY--QKRGEQ--CVDIDECT---------------------IPPYCHQ-RCVNT 231
Query: 411 IGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--G 468
GSF CQC G+ + C D +EC+ C A C N+ GSF C+C G+
Sbjct: 232 PGSFYCQCSPGFQLAANNY-TCVDINECDASN-QC--AQQCYNILGSFICQCNQGYELSS 287
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
D CED+DEC T++ C + C N G F C+C GY+ V +C DI+E
Sbjct: 288 DRLNCEDIDECRTSSYLCQYQ--CVNEPGKFSCMCPQGYQ--------VVRSRTCQDINE 337
Query: 529 CANDPTLCENGHCSNTPGGYEC 550
C E+ C N GG+ C
Sbjct: 338 CETTNECREDEMCWNYHGGFRC 359
Score = 139 bits (336), Expect = 3e-32
Identities = 75/196 (38%), Positives = 101/196 (51%), Gaps = 12/196 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++EC A C + C NL G F C C PGY+K + CVD++EC I C C
Sbjct: 173 DIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPP-YCHQR-C 228
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PG++ + CVDI+EC D C +C N GSF C+C G EL+
Sbjct: 229 VNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC-AQQCYNILGSFICQCNQGYELS 286
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
DRL+C+DIDEC +S +C C N+ G + C+C +GY V+S
Sbjct: 287 SDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGY--QVVRSRTCQDINECETTNE 343
Query: 297 CQHS--CVNTPGSYHC 310
C+ C N G + C
Sbjct: 344 CREDEMCWNYHGGFRC 359
Score = 127 bits (307), Expect = 9e-29
Identities = 100/363 (27%), Positives = 141/363 (38%), Gaps = 38/363 (10%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GYE D C D++EC+IV C G C N G + C + + + +
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET 88
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
G ++ + G G + ++ ++ I N A +
Sbjct: 89 QPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQR 148
Query: 264 M---GTYQCVCDEGYAQSTVK-SHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
+ +++ C GY QS R C+N GS+ C C G+ R
Sbjct: 149 IPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR 208
Query: 320 ADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLI 379
G C DIDEC P +C NT GS+ C C+ G A TC DI+EC
Sbjct: 209 --GEQCVDIDECT--IPPYCHQRCVNTPGSFYCQCSPGF--QLAANNYTCVDINEC---- 258
Query: 380 STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECE 439
C A C+N +GSF+CQC GY + ++ C D DEC
Sbjct: 259 -----------------DASNQC-AQQCYNILGSFICQCNQGYELSSDR-LNCEDIDECR 299
Query: 440 LGTCDCHPAADCINLPGSFQCRCRDGWR-GDGATCEDVDECLTNNGGCHPRATCANTDGS 498
+ C C+N PG F C C G++ TC+D++EC T N C C N G
Sbjct: 300 TSSYLCQ--YQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTN-ECREDEMCWNYHGG 356
Query: 499 FRC 501
FRC
Sbjct: 357 FRC 359
Score = 116 bits (278), Expect = 3e-25
Identities = 77/242 (31%), Positives = 106/242 (43%), Gaps = 33/242 (13%)
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKS 282
S R +C G E + + C+DIDEC+ + C ++ C N G++ C C GY + +
Sbjct: 154 SHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK---RG 209
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ 342
C CVNTPGS++C C G+ L A+ +C DI+EC + C Q
Sbjct: 210 EQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC-AQQ 267
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
C N +GS+ C C G + + C+DIDEC LC
Sbjct: 268 CYNILGSFICQCNQGY--ELSSDRLNCEDIDECR--------------------TSSYLC 305
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
C N G F C CP GY V + C D +ECE T +C C N G F+C
Sbjct: 306 -QYQCVNEPGKFSCMCPQGYQV--VRSRTCQDINECET-TNECREDEMCWNYHGGFRCYP 361
Query: 463 RD 464
R+
Sbjct: 362 RN 363
Score = 107 bits (257), Expect = 1e-22
Identities = 63/161 (39%), Positives = 82/161 (50%), Gaps = 20/161 (12%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N GSF CQCP GY + EQ C D DEC + CH C+N PGSF C+C G+
Sbjct: 190 CINLRGSFACQCPPGYQKRGEQ---CVDIDECTIPPY-CHQR--CVNTPGSFYCQCSPGF 243
Query: 467 R--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ + TC D++EC +N C + C N GSF C C+ GY+ L +C
Sbjct: 244 QLAANNYTCVDINECDASN-QCAQQ--CYNILGSFICQCNQGYELSSDRL-------NCE 293
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DIDEC LC+ C N PG + C C G+ + R+C
Sbjct: 294 DIDECRTSSYLCQY-QCVNEPGKFSCMCPQGY-QVVRSRTC 332
Score = 103 bits (246), Expect = 2e-21
Identities = 57/149 (38%), Positives = 75/149 (50%), Gaps = 14/149 (9%)
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
QC GY + + C D DEC GT +C CINL GSF C+C G++ G C D+
Sbjct: 158 QCAAGY--EQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDI 215
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC T CH R C NT GSF C C G+ + Y+CVDI+EC + C
Sbjct: 216 DEC-TIPPYCHQR--CVNTPGSFYCQCSPGF-------QLAANNYTCVDINEC-DASNQC 264
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C N G + C C+ G+ ++D +C
Sbjct: 265 AQ-QCYNILGSFICQCNQGYELSSDRLNC 292
Score = 77.4 bits (182), Expect = 1e-13
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 12/111 (10%)
Query: 457 SFQCRCRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
S + +C G+ + + C+D+DEC C C N GSF C C GY+ G
Sbjct: 154 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE--- 210
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CVDIDEC P C C NTPG + C C GF AA+ +C+
Sbjct: 211 ------QCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCV 253
>AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like sequence 2
isofor protein.
Length = 810
Score = 146 bits (353), Expect = 2e-34
Identities = 88/232 (37%), Positives = 112/232 (48%), Gaps = 47/232 (20%)
Query: 300 SCVNTPGSYHCTCREGWH-----LRADGRSCRDIDECAGGAR-PCGG-GQCRNTVGSYTC 352
SCVN C C G+ + +C DI+ECA ++ CG C NT GSY C
Sbjct: 38 SCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDC 94
Query: 353 TCTDGLVPSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA- 404
C+ G P +GAK TCQD+DEC Q P LC +
Sbjct: 95 VCSPGYEP-VSGAKTFKNESENTCQDVDECQ--------------------QNPRLCKSY 133
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
G+C NT+GS+ CQC G+ +KPE CTD +EC G CH + C+N GS+QCRCR
Sbjct: 134 GTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 193
Query: 465 GWR--------GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
GW+ + CEDVDEC + C C NT GS+ C C G+K
Sbjct: 194 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 128 bits (308), Expect = 7e-29
Identities = 78/204 (38%), Positives = 98/204 (48%), Gaps = 28/204 (13%)
Query: 143 CDCFPGYEKDSK-----NHTCVDVNECEIVDGV-CGD-GDCHNTEGSFTCHCRPGYK--- 192
C C PG+ S+ TC D+NEC + V CG DC NTEGS+ C C PGY+
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 193 -----ADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELAP-DRLSCKDI 245
++ C D+DEC N LC+ G CVNT GS+ C+C G +L P D C D+
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDV 164
Query: 246 DECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC---QHS- 300
+EC+ C S+ C N +G+YQC C G+ Q S C QH
Sbjct: 165 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGW-QPIPGSPNGPNNTVCEDVDECSSGQHQC 223
Query: 301 -----CVNTPGSYHCTCREGWHLR 319
C NT GSY C CR GW R
Sbjct: 224 DSSTVCFNTVGSYSCRCRPGWKPR 247
Score = 118 bits (285), Expect = 4e-26
Identities = 64/178 (35%), Positives = 90/178 (50%), Gaps = 20/178 (11%)
Query: 118 EVNECAAFPGL-CGH-GRCRNLLGGFTCDCFPGYE--------KDSKNHTCVDVNECEIV 167
++NECA + CG C N G + C C PGYE K+ +TC DV+EC+
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYK-ADDFSKICVDIDECADNDALCRGG-RCVNTAGS 224
+C G C NT GS+TC C PG+K + K+C D++EC C C+N GS
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 225 FRCECGHGME------LAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGY 275
++C C G + P+ C+D+DECS C S+ C N +G+Y C C G+
Sbjct: 187 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 106 bits (255), Expect = 2e-22
Identities = 71/216 (32%), Positives = 89/216 (41%), Gaps = 33/216 (15%)
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKI-------CVDIDECADNDALCRG--GRCVNTAG 223
D C N C C PG+ + FS+I C DI+ECA + G C NT G
Sbjct: 36 DSSCVNATA---CRCNPGFSS--FSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEG 90
Query: 224 SFRCECGHGMELAP--------DRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEG 274
S+ C C G E +C+D+DEC +C S G C N +G+Y C C G
Sbjct: 91 SYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG 150
Query: 275 YAQSTVKSHXXXXXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHL------RADGRSC 325
+ HS C+N GSY C CR GW + C
Sbjct: 151 FKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 210
Query: 326 RDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVP 360
D+DEC+ G C C NTVGSY+C C G P
Sbjct: 211 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Score = 102 bits (244), Expect = 4e-21
Identities = 78/248 (31%), Positives = 105/248 (42%), Gaps = 43/248 (17%)
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP-SAAGAKP--TCQDIDECADLISTII 383
+ + G AR C Q + V + C C G S P TC DI+ECA T+
Sbjct: 22 ETQDSRGCARWCP--QDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECA----TLS 75
Query: 384 MMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGY-------SVKPEQGPACTDD 435
+S CG S C NT GS+ C C GY + K E C D
Sbjct: 76 KVS---------------CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATC 492
DEC+ C C+N GS+ C+C G++ D C DV+EC + CH C
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 180
Query: 493 ANTDGSFRCLCDTGYK---GDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGY 548
N GS++C C G++ G G C D+DEC++ C++ C NT G Y
Sbjct: 181 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCE----DVDECSSGQHQCDSSTVCFNTVGSY 236
Query: 549 ECDCDVGF 556
C C G+
Sbjct: 237 SCRCRPGW 244
Score = 76.6 bits (180), Expect = 2e-13
Identities = 45/133 (33%), Positives = 65/133 (48%), Gaps = 16/133 (12%)
Query: 445 CHPAADCINLPGSFQCRCRDGWRGDGA-------TCEDVDECLT-NNGGCHPRATCANTD 496
C + C+N CRC G+ TC+D++EC T + C + C NT+
Sbjct: 33 CPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 89
Query: 497 GSFRCLCDTGYKGDGYGLRTVC--CVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCD 553
GS+ C+C GY+ G +T +C D+DEC +P LC++ G C NT G Y C C
Sbjct: 90 GSYDCVCSPGYEPVS-GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCL 148
Query: 554 VGF-TRAADGRSC 565
GF + D + C
Sbjct: 149 PGFKLKPEDPKLC 161
>AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2
protein.
Length = 823
Score = 146 bits (353), Expect = 2e-34
Identities = 88/232 (37%), Positives = 112/232 (48%), Gaps = 47/232 (20%)
Query: 300 SCVNTPGSYHCTCREGWH-----LRADGRSCRDIDECAGGAR-PCGG-GQCRNTVGSYTC 352
SCVN C C G+ + +C DI+ECA ++ CG C NT GSY C
Sbjct: 38 SCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDC 94
Query: 353 TCTDGLVPSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA- 404
C+ G P +GAK TCQD+DEC Q P LC +
Sbjct: 95 VCSPGYEP-VSGAKTFKNESENTCQDVDECQ--------------------QNPRLCKSY 133
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
G+C NT+GS+ CQC G+ +KPE CTD +EC G CH + C+N GS+QCRCR
Sbjct: 134 GTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 193
Query: 465 GWR--------GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
GW+ + CEDVDEC + C C NT GS+ C C G+K
Sbjct: 194 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 128 bits (308), Expect = 7e-29
Identities = 78/204 (38%), Positives = 98/204 (48%), Gaps = 28/204 (13%)
Query: 143 CDCFPGYEKDSK-----NHTCVDVNECEIVDGV-CGD-GDCHNTEGSFTCHCRPGYK--- 192
C C PG+ S+ TC D+NEC + V CG DC NTEGS+ C C PGY+
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 193 -----ADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELAP-DRLSCKDI 245
++ C D+DEC N LC+ G CVNT GS+ C+C G +L P D C D+
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDV 164
Query: 246 DECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC---QHS- 300
+EC+ C S+ C N +G+YQC C G+ Q S C QH
Sbjct: 165 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGW-QPIPGSPNGPNNTVCEDVDECSSGQHQC 223
Query: 301 -----CVNTPGSYHCTCREGWHLR 319
C NT GSY C CR GW R
Sbjct: 224 DSSTVCFNTVGSYSCRCRPGWKPR 247
Score = 118 bits (285), Expect = 4e-26
Identities = 64/178 (35%), Positives = 90/178 (50%), Gaps = 20/178 (11%)
Query: 118 EVNECAAFPGL-CGH-GRCRNLLGGFTCDCFPGYE--------KDSKNHTCVDVNECEIV 167
++NECA + CG C N G + C C PGYE K+ +TC DV+EC+
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYK-ADDFSKICVDIDECADNDALCRGG-RCVNTAGS 224
+C G C NT GS+TC C PG+K + K+C D++EC C C+N GS
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 225 FRCECGHGME------LAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGY 275
++C C G + P+ C+D+DECS C S+ C N +G+Y C C G+
Sbjct: 187 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 106 bits (255), Expect = 2e-22
Identities = 71/216 (32%), Positives = 89/216 (41%), Gaps = 33/216 (15%)
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKI-------CVDIDECADNDALCRG--GRCVNTAG 223
D C N C C PG+ + FS+I C DI+ECA + G C NT G
Sbjct: 36 DSSCVNATA---CRCNPGFSS--FSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEG 90
Query: 224 SFRCECGHGMELAP--------DRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEG 274
S+ C C G E +C+D+DEC +C S G C N +G+Y C C G
Sbjct: 91 SYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG 150
Query: 275 YAQSTVKSHXXXXXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHL------RADGRSC 325
+ HS C+N GSY C CR GW + C
Sbjct: 151 FKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 210
Query: 326 RDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVP 360
D+DEC+ G C C NTVGSY+C C G P
Sbjct: 211 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Score = 102 bits (244), Expect = 4e-21
Identities = 78/248 (31%), Positives = 105/248 (42%), Gaps = 43/248 (17%)
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP-SAAGAKP--TCQDIDECADLISTII 383
+ + G AR C Q + V + C C G S P TC DI+ECA T+
Sbjct: 22 ETQDSRGCARWCP--QDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECA----TLS 75
Query: 384 MMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGY-------SVKPEQGPACTDD 435
+S CG S C NT GS+ C C GY + K E C D
Sbjct: 76 KVS---------------CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATC 492
DEC+ C C+N GS+ C+C G++ D C DV+EC + CH C
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 180
Query: 493 ANTDGSFRCLCDTGYK---GDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGY 548
N GS++C C G++ G G C D+DEC++ C++ C NT G Y
Sbjct: 181 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCE----DVDECSSGQHQCDSSTVCFNTVGSY 236
Query: 549 ECDCDVGF 556
C C G+
Sbjct: 237 SCRCRPGW 244
Score = 76.6 bits (180), Expect = 2e-13
Identities = 45/133 (33%), Positives = 65/133 (48%), Gaps = 16/133 (12%)
Query: 445 CHPAADCINLPGSFQCRCRDGWRGDGA-------TCEDVDECLT-NNGGCHPRATCANTD 496
C + C+N CRC G+ TC+D++EC T + C + C NT+
Sbjct: 33 CPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 89
Query: 497 GSFRCLCDTGYKGDGYGLRTVC--CVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCD 553
GS+ C+C GY+ G +T +C D+DEC +P LC++ G C NT G Y C C
Sbjct: 90 GSYDCVCSPGYEPVS-GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCL 148
Query: 554 VGF-TRAADGRSC 565
GF + D + C
Sbjct: 149 PGFKLKPEDPKLC 161
>AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 isoform b
variant protein.
Length = 418
Score = 146 bits (353), Expect = 2e-34
Identities = 94/279 (33%), Positives = 134/279 (48%), Gaps = 20/279 (7%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GYE+ S+++ C D++EC C D C N GSF C C PGY+ + CVDI
Sbjct: 84 CAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDI 140
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C RCVNT GSF C+C G +LA + +C DI+EC S C+ C N
Sbjct: 141 DECTI-PPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDINECD-ASNQCAQ-QCYNI 196
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
+G++ C C++GY S+ + + CQ+ CVN PG + C C +G+ + R
Sbjct: 197 LGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNQPGKFSCMCPQGYQV-VRSR 255
Query: 324 SCRDIDECAGGARPCGGGQCRNTVGSYTC----TCTDG--LVPSAAGAKPTCQDIDECAD 377
+C+DI+EC C N G + C C D L P P + C +
Sbjct: 256 TCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CRE 313
Query: 378 LISTII--MMSVDELQKSVDPQIPELCGAGSCHNTIGSF 414
L +I+ MS+ +SV I ++ NTI +F
Sbjct: 314 LPQSIVYKYMSI-RSDRSVPSDIFQIQATTIYANTINTF 351
Score = 140 bits (339), Expect = 1e-32
Identities = 76/196 (38%), Positives = 101/196 (51%), Gaps = 12/196 (6%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+++EC A C + C NL G F C C PGY+K + CVD++EC I C C
Sbjct: 98 DIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPP-YCHQR-C 153
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PG++ + CVDI+EC D C +C N GSF C+C G EL+
Sbjct: 154 VNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC-AQQCYNILGSFICQCNQGYELS 211
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
DRL+C+DIDEC +S +C C NQ G + C+C +GY V+S
Sbjct: 212 SDRLNCEDIDECRTSSYLCQY-QCVNQPGKFSCMCPQGY--QVVRSRTCQDINECETTNE 268
Query: 297 CQHS--CVNTPGSYHC 310
C+ C N G + C
Sbjct: 269 CREDEMCWNYHGGFRC 284
Score = 118 bits (283), Expect = 7e-26
Identities = 82/247 (33%), Positives = 107/247 (43%), Gaps = 44/247 (17%)
Query: 307 SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGA 365
S+ C G+ +++ C+DIDEC G C Q C N GS+ C C G G
Sbjct: 79 SHRIQCAAGYE-QSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGY--QKRGE 135
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVK 425
+ C DIDEC IP C C NT GSF CQC G+ +
Sbjct: 136 Q--CVDIDECT---------------------IPPYCHQ-RCVNTPGSFYCQCSPGFQLA 171
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNN 483
C D +EC+ C A C N+ GSF C+C G+ D CED+DEC T++
Sbjct: 172 ANNY-TCVDINECDASN-QC--AQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSS 227
Query: 484 GGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSN 543
C + C N G F C+C GY+ V +C DI+EC E+ C N
Sbjct: 228 YLCQYQ--CVNQPGKFSCMCPQGYQ--------VVRSRTCQDINECETTNECREDEMCWN 277
Query: 544 TPGGYEC 550
GG+ C
Sbjct: 278 YHGGFRC 284
Score = 116 bits (278), Expect = 3e-25
Identities = 77/242 (31%), Positives = 106/242 (43%), Gaps = 33/242 (13%)
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKS 282
S R +C G E + + C+DIDEC+ + C ++ C N G++ C C GY + +
Sbjct: 79 SHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQK---RG 134
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ 342
C CVNTPGS++C C G+ L A+ +C DI+EC + C Q
Sbjct: 135 EQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC-AQQ 192
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
C N +GS+ C C G + + C+DIDEC LC
Sbjct: 193 CYNILGSFICQCNQGY--ELSSDRLNCEDIDECR--------------------TSSYLC 230
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
C N G F C CP GY V + C D +ECE T +C C N G F+C
Sbjct: 231 -QYQCVNQPGKFSCMCPQGYQV--VRSRTCQDINECET-TNECREDEMCWNYHGGFRCYP 286
Query: 463 RD 464
R+
Sbjct: 287 RN 288
Score = 107 bits (257), Expect = 1e-22
Identities = 63/161 (39%), Positives = 82/161 (50%), Gaps = 20/161 (12%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N GSF CQCP GY + EQ C D DEC + CH C+N PGSF C+C G+
Sbjct: 115 CINLRGSFACQCPPGYQKRGEQ---CVDIDECTIPPY-CHQR--CVNTPGSFYCQCSPGF 168
Query: 467 R--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ + TC D++EC +N C + C N GSF C C+ GY+ L +C
Sbjct: 169 QLAANNYTCVDINECDASN-QCAQQ--CYNILGSFICQCNQGYELSSDRL-------NCE 218
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DIDEC LC+ C N PG + C C G+ + R+C
Sbjct: 219 DIDECRTSSYLCQY-QCVNQPGKFSCMCPQGY-QVVRSRTC 257
Score = 103 bits (246), Expect = 2e-21
Identities = 57/149 (38%), Positives = 75/149 (50%), Gaps = 14/149 (9%)
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
QC GY + + C D DEC GT +C CINL GSF C+C G++ G C D+
Sbjct: 83 QCAAGY--EQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDI 140
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC 536
DEC T CH R C NT GSF C C G+ + Y+CVDI+EC + C
Sbjct: 141 DEC-TIPPYCHQR--CVNTPGSFYCQCSPGF-------QLAANNYTCVDINEC-DASNQC 189
Query: 537 ENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C N G + C C+ G+ ++D +C
Sbjct: 190 AQ-QCYNILGSFICQCNQGYELSSDRLNC 217
Score = 77.4 bits (182), Expect = 1e-13
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 12/111 (10%)
Query: 457 SFQCRCRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
S + +C G+ + + C+D+DEC C C N GSF C C GY+ G
Sbjct: 79 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE--- 135
Query: 516 TVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
CVDIDEC P C C NTPG + C C GF AA+ +C+
Sbjct: 136 ------QCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCV 178
>AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane helix
receptor protein.
Length = 837
Score = 146 bits (353), Expect = 2e-34
Identities = 88/232 (37%), Positives = 112/232 (48%), Gaps = 47/232 (20%)
Query: 300 SCVNTPGSYHCTCREGWH-----LRADGRSCRDIDECAGGAR-PCGG-GQCRNTVGSYTC 352
SCVN C C G+ + +C DI+ECA ++ CG C NT GSY C
Sbjct: 39 SCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDC 95
Query: 353 TCTDGLVPSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA- 404
C+ G P +GAK TCQD+DEC Q P LC +
Sbjct: 96 VCSPGYEP-VSGAKTFKNESENTCQDVDECQ--------------------QNPRLCKSY 134
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
G+C NT+GS+ CQC G+ +KPE CTD +EC G CH + C+N GS+QCRCR
Sbjct: 135 GTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 194
Query: 465 GWR--------GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
GW+ + CEDVDEC + C C NT GS+ C C G+K
Sbjct: 195 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 246
Score = 128 bits (308), Expect = 7e-29
Identities = 78/204 (38%), Positives = 98/204 (48%), Gaps = 28/204 (13%)
Query: 143 CDCFPGYEKDSK-----NHTCVDVNECEIVDGV-CGD-GDCHNTEGSFTCHCRPGYK--- 192
C C PG+ S+ TC D+NEC + V CG DC NTEGS+ C C PGY+
Sbjct: 46 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 105
Query: 193 -----ADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELAP-DRLSCKDI 245
++ C D+DEC N LC+ G CVNT GS+ C+C G +L P D C D+
Sbjct: 106 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDV 165
Query: 246 DECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC---QHS- 300
+EC+ C S+ C N +G+YQC C G+ Q S C QH
Sbjct: 166 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGW-QPIPGSPNGPNNTVCEDVDECSSGQHQC 224
Query: 301 -----CVNTPGSYHCTCREGWHLR 319
C NT GSY C CR GW R
Sbjct: 225 DSSTVCFNTVGSYSCRCRPGWKPR 248
Score = 118 bits (285), Expect = 4e-26
Identities = 64/178 (35%), Positives = 90/178 (50%), Gaps = 20/178 (11%)
Query: 118 EVNECAAFPGL-CGH-GRCRNLLGGFTCDCFPGYE--------KDSKNHTCVDVNECEIV 167
++NECA + CG C N G + C C PGYE K+ +TC DV+EC+
Sbjct: 68 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 127
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYK-ADDFSKICVDIDECADNDALCRGG-RCVNTAGS 224
+C G C NT GS+TC C PG+K + K+C D++EC C C+N GS
Sbjct: 128 PRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGS 187
Query: 225 FRCECGHGME------LAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGY 275
++C C G + P+ C+D+DECS C S+ C N +G+Y C C G+
Sbjct: 188 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 245
Score = 106 bits (255), Expect = 2e-22
Identities = 71/216 (32%), Positives = 89/216 (41%), Gaps = 33/216 (15%)
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKI-------CVDIDECADNDALCRG--GRCVNTAG 223
D C N C C PG+ + FS+I C DI+ECA + G C NT G
Sbjct: 37 DSSCVNATA---CRCNPGFSS--FSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEG 91
Query: 224 SFRCECGHGMELAP--------DRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEG 274
S+ C C G E +C+D+DEC +C S G C N +G+Y C C G
Sbjct: 92 SYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG 151
Query: 275 YAQSTVKSHXXXXXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHL------RADGRSC 325
+ HS C+N GSY C CR GW + C
Sbjct: 152 FKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 211
Query: 326 RDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVP 360
D+DEC+ G C C NTVGSY+C C G P
Sbjct: 212 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 247
Score = 102 bits (244), Expect = 4e-21
Identities = 78/248 (31%), Positives = 105/248 (42%), Gaps = 43/248 (17%)
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP-SAAGAKP--TCQDIDECADLISTII 383
+ + G AR C Q + V + C C G S P TC DI+ECA T+
Sbjct: 23 ETQDSRGCARWCP--QDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECA----TLS 76
Query: 384 MMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGY-------SVKPEQGPACTDD 435
+S CG S C NT GS+ C C GY + K E C D
Sbjct: 77 KVS---------------CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 121
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATC 492
DEC+ C C+N GS+ C+C G++ D C DV+EC + CH C
Sbjct: 122 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 181
Query: 493 ANTDGSFRCLCDTGYK---GDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGY 548
N GS++C C G++ G G C D+DEC++ C++ C NT G Y
Sbjct: 182 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCE----DVDECSSGQHQCDSSTVCFNTVGSY 237
Query: 549 ECDCDVGF 556
C C G+
Sbjct: 238 SCRCRPGW 245
Score = 76.6 bits (180), Expect = 2e-13
Identities = 45/133 (33%), Positives = 65/133 (48%), Gaps = 16/133 (12%)
Query: 445 CHPAADCINLPGSFQCRCRDGWRGDGA-------TCEDVDECLT-NNGGCHPRATCANTD 496
C + C+N CRC G+ TC+D++EC T + C + C NT+
Sbjct: 34 CPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 90
Query: 497 GSFRCLCDTGYKGDGYGLRTVC--CVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCD 553
GS+ C+C GY+ G +T +C D+DEC +P LC++ G C NT G Y C C
Sbjct: 91 GSYDCVCSPGYEPVS-GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCL 149
Query: 554 VGF-TRAADGRSC 565
GF + D + C
Sbjct: 150 PGFKLKPEDPKLC 162
>Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.
Length = 1223
Score = 144 bits (348), Expect = 1e-33
Identities = 137/480 (28%), Positives = 188/480 (39%), Gaps = 84/480 (17%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG 174
Q++ NEC P L C+NL+GG+ CDC PG+ K C ++VN+C G C G
Sbjct: 406 QLDANECEGKPCLNAFS-CKNLIGGYYCDCIPGW----KGINCHINVNDCR---GQCQHG 457
Query: 175 D-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C G+ ++ DECA + GG C + A F C C G
Sbjct: 458 GTCKDLVNGYQCVCPRGFGGRHCE---LERDECASSPCHS-GGLCEDLADGFHCHCPQGF 513
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVC--DEGYAQSTVK--------- 281
P L D+D C + C NGA C N G Y C C D G +V
Sbjct: 514 S-GP--LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGAC 568
Query: 282 -------SHXXXXXXXXXXXXRC-QHS-CVNTPG-SYHCTCREGWHLRADGRSCRD-IDE 330
S C H CV+ PG ++ C C G+ G C + ID+
Sbjct: 569 RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGF----TGTYCHENIDD 624
Query: 331 CAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPT------CQDIDECADLISTII 383
C G +PC GG C + V ++ C C G P C C DL++
Sbjct: 625 CLG--QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 682
Query: 384 MMSVDELQKSVDPQIPELCGA------GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
D + C A G+C+++ +F C CP G+ +G C
Sbjct: 683 CACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGW-----KGSTCAVAKN 737
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTNNGGCHPRATCANTD 496
C C+ SF C CRDGW +G TC + ++C N C+ C +
Sbjct: 738 SSCLPNPCVNGGTCVGSGASFSCICRDGW--EGRTCTHNTNDC--NPLPCYNGGICVDGV 793
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
FRC C G+ G C ++IDEC + P C G C + GY C C G
Sbjct: 794 NWFRCECAPGFAGPD------C----RINIDECQSSP--CAYGATCVDEINGYRCSCPPG 841
Score = 133 bits (321), Expect = 2e-30
Identities = 131/469 (27%), Positives = 182/469 (38%), Gaps = 100/469 (21%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGG-FTCDCFPGYEK---DSKNHTCVDVNECEIVDGVCGD 173
++N C + G C N + C C GY + H C N C
Sbjct: 291 DLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTS-NPC------ANG 343
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
G CH F CHC G+ + DIDECA N GG CV+ F C C
Sbjct: 344 GSCHEVPSGFECHCPSGWSGPTCAS--ADIDECASNPC-AAGGTCVDQVDGFECICPEQW 400
Query: 234 ELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A +L D +EC C N +C+N +G Y C C G+ + H
Sbjct: 401 VGATCQL---DANECE--GKPCLNAFSCKNLIGGYYCDCIPGW--KGINCH----INVND 449
Query: 293 XXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVG 348
+CQH +C + Y C C G+ GR C + DECA + PC GG C +
Sbjct: 450 CRGQCQHGGTCKDLVNGYQCVCPRGF----GGRHCELERDECA--SSPCHSGGLCEDLAD 503
Query: 349 SYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS- 406
+ C C G + P C+ D+D C P C G+
Sbjct: 504 GFHCHCPQGF------SGPLCEVDVDLCE----------------------PSPCRNGAR 535
Query: 407 CHNTIGSFVCQCPDGYSVK-------PEQGPACTDDDECEL-------GTCD---CHPAA 449
C+N G + C CPD + K P G AC D C GT C P
Sbjct: 536 CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHG 595
Query: 450 DCINLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
C++ P G+F C C G+ G E++D+CL C TC + +FRC C +G++
Sbjct: 596 RCVSQPGGNFSCICDSGFTGTYCH-ENIDDCL--GQPCRNGGTCIDEVDAFRCFCPSGWE 652
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
G+ +C + ++C DP C + G C + + C CD G+
Sbjct: 653 GE------LC----DTNPNDCLPDP--CHSRGRCYDLVNDFYCACDDGW 689
Score = 126 bits (304), Expect = 2e-28
Identities = 119/459 (25%), Positives = 183/459 (39%), Gaps = 68/459 (14%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG-D 175
+++ECA+ P G G C + + GF C C + TC +D NECE C +
Sbjct: 370 DIDECASNPCAAG-GTCVDQVDGFECIC----PEQWVGATCQLDANECE--GKPCLNAFS 422
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGME 234
C N G + C C PG+K + +++++C C+ GG C + ++C C G
Sbjct: 423 CKNLIGGYYCDCIPGWKGINCH---INVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGFG 476
Query: 235 LAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXX 294
L + DEC+ +S S G CE+ + C C +G++ +
Sbjct: 477 GRHCEL---ERDECA-SSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---VDVDLCEPSP 529
Query: 295 XRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC 354
R C N G Y+C C + + G++C E PC GG CR G C
Sbjct: 530 CRNGARCYNLEGDYYCACPDDF----GGKNCSVPRE------PCPGGACRVIDG---CGS 576
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDE------LQKSVDPQIPELC-GAGSC 407
G A C C D +++D + + C G+C
Sbjct: 577 DAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTC 636
Query: 408 HNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
+ + +F C CP G+ +G C T+ ++C C H C +L F C C DGW
Sbjct: 637 IDEVDAFRCFCPSGW-----EGELCDTNPNDCLPDPC--HSRGRCYDLVNDFYCACDDGW 689
Query: 467 RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI 526
+ G TC E + C TC ++ +FRC C G+KG + C V
Sbjct: 690 K--GKTCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKG------STCAV---AKN 737
Query: 527 DECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C +P + G C + + C C G+ +GR+C
Sbjct: 738 SSCLPNPCV-NGGTCVGSGASFSCICRDGW----EGRTC 771
Score = 118 bits (285), Expect = 4e-26
Identities = 111/432 (25%), Positives = 172/432 (39%), Gaps = 71/432 (16%)
Query: 117 MEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
+ VN+C G C HG C++L+ G+ C C G+ H ++ +EC C G
Sbjct: 445 INVNDCR---GQCQHGGTCKDLVNGYQCVCPRGF---GGRHCELERDEC--ASSPCHSGG 496
Query: 176 -CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGG-RCVNTAGSFRCECGH- 231
C + F CHC G+ +C VD+D C + CR G RC N G + C C
Sbjct: 497 LCEDLADGFHCHCPQGFSGP----LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDD 550
Query: 232 --GMELAPDRL-----SCKDIDEC----------SITSGICS-NGACENQMG-TYQCVCD 272
G + R +C+ ID C + SG+C +G C +Q G + C+CD
Sbjct: 551 FGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICD 610
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDEC 331
G+ + + R +C++ ++ C C GW +G C + ++C
Sbjct: 611 SGFTGTYCHENIDDCLGQPC---RNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDC 663
Query: 332 AGGARPCGG-GQCRNTVGSYTCTCTDGLVPSAAGAKP------TCQDIDECADLISTIIM 384
PC G+C + V + C C DG ++ TC + C D T
Sbjct: 664 LPD--PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC 721
Query: 385 MSVDELQKSV------DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
+ S +P C G+C + SF C C DG+ +G CT +
Sbjct: 722 ACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGW-----EGRTCTHNTN 776
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDG 497
+ C+ C++ F+C C G+ G ++DEC + C ATC +
Sbjct: 777 -DCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRI-NIDEC--QSSPCAYGATCVDEIN 832
Query: 498 SFRCLCDTGYKG 509
+RC C G G
Sbjct: 833 GYRCSCPPGRAG 844
Score = 90.2 bits (214), Expect = 2e-17
Identities = 79/280 (28%), Positives = 114/280 (40%), Gaps = 48/280 (17%)
Query: 301 CVNTPGSYHCTCREGWHLRAD----GRSC-RDIDECAGGARPC-GGGQCRNT-VGSYTCT 353
CV PG H +C E W + G C +D++ C G PC GG C N Y CT
Sbjct: 260 CVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYC-GSHHPCTNGGTCINAEPDQYRCT 318
Query: 354 CTDGL-------VPSAAGAKP-----TCQDIDECADLISTIIMMSVDELQKSVDPQIPEL 401
C DG A + P +C ++ + +D
Sbjct: 319 CPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCASADIDECASNP 378
Query: 402 CGA-GSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQ 459
C A G+C + + F C CP+ + G C D +ECE G C A C NL G +
Sbjct: 379 CAAGGTCVDQVDGFECICPEQW-----VGATCQLDANECE-GK-PCLNAFSCKNLIGGYY 431
Query: 460 CRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C C GW+ G C +V++C G C TC + ++C+C G+ G
Sbjct: 432 CDCIPGWK--GINCHINVNDC---RGQCQHGGTCKDLVNGYQCVCPRGFGGR-------- 478
Query: 519 CVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
+ ++ DECA+ P C +G C + G+ C C GF+
Sbjct: 479 --HCELERDECASSP--CHSGGLCEDLADGFHCHCPQGFS 514
Score = 78.6 bits (185), Expect = 5e-14
Identities = 69/252 (27%), Positives = 96/252 (38%), Gaps = 35/252 (13%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGG-----QCRNTVGSYTCTCTDGLVPSAAGAK 366
C +GW G+ C++ C G GG +CR + G C D VP
Sbjct: 215 CMDGWM----GKECKEA-VCKQGCNLLHGGCTVPGECRCSYGWQGRFC-DECVPYPGCVH 268
Query: 367 PTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI-GSFVCQCPDGYSVK 425
+C + +C + ++ +L G+C N + C CPDGYS
Sbjct: 269 GSCVEPWQCNCETNWGGLLCDKDLNYCGSHH--PCTNGGTCINAEPDQYRCTCPDGYS-- 324
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGG 485
G C + E + C C +P F+C C GW G D+DEC +N
Sbjct: 325 ---GRNC-EKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCASADIDECASN--P 378
Query: 486 CHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNT 544
C TC + F C+C + G C +D +EC P C N C N
Sbjct: 379 CAAGGTCVDQVDGFECICPEQWVG------ATC----QLDANECEGKP--CLNAFSCKNL 426
Query: 545 PGGYECDCDVGF 556
GGY CDC G+
Sbjct: 427 IGGYYCDCIPGW 438
Score = 50.4 bits (115), Expect = 2e-05
Identities = 35/120 (29%), Positives = 50/120 (41%), Gaps = 19/120 (15%)
Query: 443 CD-CHPAADCIN--LPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTD-G 497
CD C P C++ +QC C W G C+ D++ C +++ C TC N +
Sbjct: 257 CDECVPYPGCVHGSCVEPWQCNCETNW--GGLLCDKDLNYCGSHHP-CTNGGTCINAEPD 313
Query: 498 SFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
+RC C GY G C + CAN G C P G+EC C G++
Sbjct: 314 QYRCTCPDGYSGRNCEKAEHACTSN-----PCAN------GGSCHEVPSGFECHCPSGWS 362
>AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 144 bits (348), Expect = 1e-33
Identities = 137/480 (28%), Positives = 188/480 (39%), Gaps = 84/480 (17%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG 174
Q++ NEC P L C+NL+GG+ CDC PG+ K C ++VN+C G C G
Sbjct: 421 QLDANECEGKPCLNAFS-CKNLIGGYYCDCIPGW----KGINCHINVNDCR---GQCQHG 472
Query: 175 D-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C G+ ++ DECA + GG C + A F C C G
Sbjct: 473 GTCKDLVNGYQCVCPRGFGGRHCE---LERDECASSPCHS-GGLCEDLADGFHCHCPQGF 528
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVC--DEGYAQSTVK--------- 281
P L D+D C + C NGA C N G Y C C D G +V
Sbjct: 529 S-GP--LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGAC 583
Query: 282 -------SHXXXXXXXXXXXXRC-QHS-CVNTPG-SYHCTCREGWHLRADGRSCRD-IDE 330
S C H CV+ PG ++ C C G+ G C + ID+
Sbjct: 584 RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGF----TGTYCHENIDD 639
Query: 331 CAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPT------CQDIDECADLISTII 383
C G +PC GG C + V ++ C C G P C C DL++
Sbjct: 640 CLG--QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 697
Query: 384 MMSVDELQKSVDPQIPELCGA------GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
D + C A G+C+++ +F C CP G+ +G C
Sbjct: 698 CACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGW-----KGSTCAVAKN 752
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTNNGGCHPRATCANTD 496
C C+ SF C CRDGW +G TC + ++C N C+ C +
Sbjct: 753 SSCLPNPCVNGGTCVGSGASFSCICRDGW--EGRTCTHNTNDC--NPLPCYNGGICVDGV 808
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
FRC C G+ G C ++IDEC + P C G C + GY C C G
Sbjct: 809 NWFRCECAPGFAGPD------C----RINIDECQSSP--CAYGATCVDEINGYRCSCPPG 856
Score = 132 bits (320), Expect = 2e-30
Identities = 131/469 (27%), Positives = 182/469 (38%), Gaps = 101/469 (21%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGG-FTCDCFPGYEK---DSKNHTCVDVNECEIVDGVCGD 173
++N C + G C N + C C GY + H C N C
Sbjct: 307 DLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTS-NPC------ANG 359
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
G CH F CHC G+ +DIDECA N GG CV+ F C C
Sbjct: 360 GSCHEVPSGFECHCPSGWSG---PTCALDIDECASNPC-AAGGTCVDQVDGFECICPEQW 415
Query: 234 ELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A +L D +EC C N +C+N +G Y C C G+ + H
Sbjct: 416 VGATCQL---DANECE--GKPCLNAFSCKNLIGGYYCDCIPGW--KGINCH----INVND 464
Query: 293 XXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVG 348
+CQH +C + Y C C G+ GR C + DECA + PC GG C +
Sbjct: 465 CRGQCQHGGTCKDLVNGYQCVCPRGF----GGRHCELERDECA--SSPCHSGGLCEDLAD 518
Query: 349 SYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS- 406
+ C C G + P C+ D+D C P C G+
Sbjct: 519 GFHCHCPQGF------SGPLCEVDVDLCE----------------------PSPCRNGAR 550
Query: 407 CHNTIGSFVCQCPDGYSVK-------PEQGPACTDDDECEL-------GTCD---CHPAA 449
C+N G + C CPD + K P G AC D C GT C P
Sbjct: 551 CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHG 610
Query: 450 DCINLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
C++ P G+F C C G+ G E++D+CL C TC + +FRC C +G++
Sbjct: 611 RCVSQPGGNFSCICDSGFTGTYCH-ENIDDCL--GQPCRNGGTCIDEVDAFRCFCPSGWE 667
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
G+ +C + ++C DP C + G C + + C CD G+
Sbjct: 668 GE------LC----DTNPNDCLPDP--CHSRGRCYDLVNDFYCACDDGW 704
Score = 127 bits (306), Expect = 1e-28
Identities = 119/460 (25%), Positives = 184/460 (40%), Gaps = 68/460 (14%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG- 174
++++ECA+ P G G C + + GF C C + TC +D NECE C +
Sbjct: 384 LDIDECASNPCAAG-GTCVDQVDGFECIC----PEQWVGATCQLDANECE--GKPCLNAF 436
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGM 233
C N G + C C PG+K + +++++C C+ GG C + ++C C G
Sbjct: 437 SCKNLIGGYYCDCIPGWKGINCH---INVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGF 490
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L + DEC+ +S S G CE+ + C C +G++ +
Sbjct: 491 GGRHCEL---ERDECA-SSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---VDVDLCEPS 543
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
R C N G Y+C C + + G++C E PC GG CR G C
Sbjct: 544 PCRNGARCYNLEGDYYCACPDDF----GGKNCSVPRE------PCPGGACRVIDG---CG 590
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDE------LQKSVDPQIPELC-GAGS 406
G A C C D +++D + + C G+
Sbjct: 591 SDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 650
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C + + +F C CP G+ +G C T+ ++C C H C +L F C C DG
Sbjct: 651 CIDEVDAFRCFCPSGW-----EGELCDTNPNDCLPDPC--HSRGRCYDLVNDFYCACDDG 703
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
W+ G TC E + C TC ++ +FRC C G+KG + C V
Sbjct: 704 WK--GKTCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKG------STCAV---AK 751
Query: 526 IDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C +P + G C + + C C G+ +GR+C
Sbjct: 752 NSSCLPNPCV-NGGTCVGSGASFSCICRDGW----EGRTC 786
Score = 118 bits (285), Expect = 4e-26
Identities = 111/432 (25%), Positives = 172/432 (39%), Gaps = 71/432 (16%)
Query: 117 MEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
+ VN+C G C HG C++L+ G+ C C G+ H ++ +EC C G
Sbjct: 460 INVNDCR---GQCQHGGTCKDLVNGYQCVCPRGF---GGRHCELERDEC--ASSPCHSGG 511
Query: 176 -CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGG-RCVNTAGSFRCECGH- 231
C + F CHC G+ +C VD+D C + CR G RC N G + C C
Sbjct: 512 LCEDLADGFHCHCPQGFSGP----LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDD 565
Query: 232 --GMELAPDRL-----SCKDIDEC----------SITSGICS-NGACENQMG-TYQCVCD 272
G + R +C+ ID C + SG+C +G C +Q G + C+CD
Sbjct: 566 FGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICD 625
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDEC 331
G+ + + R +C++ ++ C C GW +G C + ++C
Sbjct: 626 SGFTGTYCHENIDDCLGQPC---RNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDC 678
Query: 332 AGGARPCGG-GQCRNTVGSYTCTCTDGLVPSAAGAKP------TCQDIDECADLISTIIM 384
PC G+C + V + C C DG ++ TC + C D T
Sbjct: 679 LPD--PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC 736
Query: 385 MSVDELQKSV------DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
+ S +P C G+C + SF C C DG+ +G CT +
Sbjct: 737 ACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGW-----EGRTCTHNTN 791
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDG 497
+ C+ C++ F+C C G+ G ++DEC + C ATC +
Sbjct: 792 -DCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRI-NIDEC--QSSPCAYGATCVDEIN 847
Query: 498 SFRCLCDTGYKG 509
+RC C G G
Sbjct: 848 GYRCSCPPGRAG 859
Score = 91.9 bits (218), Expect = 6e-18
Identities = 82/280 (29%), Positives = 116/280 (41%), Gaps = 49/280 (17%)
Query: 301 CVNTPGSYHCTCREGWHLRAD----GRSC-RDIDECAGGARPC-GGGQCRNT-VGSYTCT 353
CV PG H +C E W + G C +D++ C G PC GG C N Y CT
Sbjct: 276 CVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYC-GSHHPCTNGGTCINAEPDQYRCT 334
Query: 354 CTDGL-------VPSAAGAKPTCQDIDECADLISTIIM-----MSVDELQKSVDPQIPEL 401
C DG A + P C + C ++ S S +D
Sbjct: 335 CPDGYSGRNCEKAEHACTSNP-CANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNP 393
Query: 402 CGA-GSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQ 459
C A G+C + + F C CP+ + G C D +ECE G C A C NL G +
Sbjct: 394 CAAGGTCVDQVDGFECICPEQW-----VGATCQLDANECE-GK-PCLNAFSCKNLIGGYY 446
Query: 460 CRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C C GW+ G C +V++C G C TC + ++C+C G+ G
Sbjct: 447 CDCIPGWK--GINCHINVNDC---RGQCQHGGTCKDLVNGYQCVCPRGFGGR-------- 493
Query: 519 CVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
+ ++ DECA+ P C +G C + G+ C C GF+
Sbjct: 494 --HCELERDECASSP--CHSGGLCEDLADGFHCHCPQGFS 529
Score = 76.2 bits (179), Expect = 3e-13
Identities = 71/253 (28%), Positives = 98/253 (38%), Gaps = 38/253 (15%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGG-----QCRNTVGSYTCTCTDGLVPSAAGAK 366
C +GW G+ C++ C G GG +CR + G C D VP
Sbjct: 231 CMDGWM----GKECKEA-VCKQGCNLLHGGCTVPGECRCSYGWQGRFC-DECVPYPGCVH 284
Query: 367 PTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI-GSFVCQCPDGYSVK 425
+C + +C + ++ +L G+C N + C CPDGYS
Sbjct: 285 GSCVEPWQCNCETNWGGLLCDKDLNYCGSHH--PCTNGGTCINAEPDQYRCTCPDGYS-- 340
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNG 484
G C + E + C C +P F+C C GW G TC D+DEC +N
Sbjct: 341 ---GRNC-EKAEHACTSNPCANGGSCHEVPSGFECHCPSGW--SGPTCALDIDECASN-- 392
Query: 485 GCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSN 543
C TC + F C+C + G C +D +EC P C N C N
Sbjct: 393 PCAAGGTCVDQVDGFECICPEQWVG------ATC----QLDANECEGKP--CLNAFSCKN 440
Query: 544 TPGGYECDCDVGF 556
GGY CDC G+
Sbjct: 441 LIGGYYCDCIPGW 453
Score = 50.4 bits (115), Expect = 2e-05
Identities = 35/120 (29%), Positives = 50/120 (41%), Gaps = 19/120 (15%)
Query: 443 CD-CHPAADCIN--LPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTD-G 497
CD C P C++ +QC C W G C+ D++ C +++ C TC N +
Sbjct: 273 CDECVPYPGCVHGSCVEPWQCNCETNW--GGLLCDKDLNYCGSHHP-CTNGGTCINAEPD 329
Query: 498 SFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
+RC C GY G C + CAN G C P G+EC C G++
Sbjct: 330 QYRCTCPDGYSGRNCEKAEHACTSN-----PCAN------GGSCHEVPSGFECHCPSGWS 378
>AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein.
Length = 448
Score = 144 bits (348), Expect = 1e-33
Identities = 79/210 (37%), Positives = 99/210 (47%), Gaps = 10/210 (4%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYKADDFSKICVDI 203
C GY+ D N CVDV+EC C C N +G +TC C GY + C+DI
Sbjct: 113 CRFGYQMDESNQ-CVDVDECATDSHQCNPTQICINMKGGYTCSCTDGYWLLEGQ--CLDI 169
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
DEC C+ C N GS+ C C G L D SC+D++EC+ T C C N
Sbjct: 170 DEC--RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECA-TENPCVQ-TCVNT 224
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
G++ C CD GY H CQH CVN PG+Y C+C G+ L D R
Sbjct: 225 YGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNR 284
Query: 324 SCRDIDECAGGARPCGGGQ-CRNTVGSYTC 352
SC+DI+EC C Q C N G + C
Sbjct: 285 SCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 142 bits (345), Expect = 2e-33
Identities = 101/327 (30%), Positives = 134/327 (40%), Gaps = 38/327 (11%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTCHCR--PGYKADD 195
G C G++ D ++ C+D++EC + C GD C N G + CH R P Y+
Sbjct: 21 GNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCHSRTNPVYRGPY 80
Query: 196 FSKICVDIDECADNDALCRGGRCVNT-AGSFRCECGHGMELAPDRLSCKDIDECSITSGI 254
+ A T + C G+ M+ + C D+DEC+ S
Sbjct: 81 SNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMD---ESNQCVDVDECATDSHQ 137
Query: 255 CS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCR 313
C+ C N G Y C C +GY CQ C N PGSY CTC
Sbjct: 138 CNPTQICINMKGGYTCSCTDGY----WLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCN 193
Query: 314 EGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDID 373
G+ L DGRSC+D++ECA PC C NT GS+ C C G G C D+D
Sbjct: 194 PGFTLNEDGRSCQDVNECA-TENPC-VQTCVNTYGSFICRCDPGYELEEDGVH--CSDMD 249
Query: 374 ECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACT 433
EC S E LC C N G++ C CP GY + + +C
Sbjct: 250 EC----------SFSEF----------LC-QHECVNQPGTYFCSCPPGY-ILLDDNRSCQ 287
Query: 434 DDDECELGTCDCHPAADCINLPGSFQC 460
D +ECE C+ C NL G F+C
Sbjct: 288 DINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 139 bits (337), Expect = 2e-32
Identities = 99/333 (29%), Positives = 145/333 (43%), Gaps = 39/333 (11%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECG-HGM 233
C + G+ C G+ D S C+DIDEC CRG CVN G + C + +
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCHSRTNPV 75
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
P + A + +C GY Q +
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGY-QMDESNQCVDVDECATD 134
Query: 294 XXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYT 351
+C + C+N G Y C+C +G+ L +G+ C DIDEC G C C N GSY+
Sbjct: 135 SHQCNPTQICINMKGGYTCSCTDGYWL-LEGQ-CLDIDECRYGY--CQQ-LCANVPGSYS 189
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
CTC G + G +CQD++ECA + +P + +C NT
Sbjct: 190 CTCNPGFTLNEDGR--SCQDVNECA----------------TENPCVQ------TCVNTY 225
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGD 469
GSF+C+C GY ++ E G C+D DEC C +C+N PG++ C C G+ D
Sbjct: 226 GSFICRCDPGYELE-EDGVHCSDMDECSFSEFLCQH--ECVNQPGTYFCSCPPGYILLDD 282
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCL 502
+C+D++EC N C+ + TC N G F+C+
Sbjct: 283 NRSCQDINECEHRNHTCNLQQTCYNLQGGFKCI 315
Score = 131 bits (317), Expect = 6e-30
Identities = 94/289 (32%), Positives = 120/289 (41%), Gaps = 42/289 (14%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLV 359
C+ +PG+ C G+ L C DIDEC C G C N G Y C V
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCHSRTNPV 75
Query: 360 ---------------PSAAGAKP-TCQDIDECADLISTIIMMSVDELQKSVDPQI----P 399
P A A P + + + + +DE + VD
Sbjct: 76 YRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDS 135
Query: 400 ELCGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSF 458
C C N G + C C DGY + Q C D DEC G C C N+PGS+
Sbjct: 136 HQCNPTQICINMKGGYTCSCTDGYWLLEGQ---CLDIDECRYGYCQ----QLCANVPGSY 188
Query: 459 QCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
C C G+ DG +C+DV+EC T N TC NT GSF C CD GY+ + G+
Sbjct: 189 SCTCNPGFTLNEDGRSCQDVNECATENPCVQ---TCVNTYGSFICRCDPGYELEEDGVH- 244
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C D+DEC+ LC++ C N PG Y C C G+ D RSC
Sbjct: 245 ------CSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSC 286
Score = 128 bits (309), Expect = 5e-29
Identities = 69/197 (35%), Positives = 95/197 (48%), Gaps = 11/197 (5%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++V+ECA C + C N+ GG+TC C GY C+D++EC G C
Sbjct: 126 VDVDECATDSHQCNPTQICINMKGGYTCSCTDGYW--LLEGQCLDIDECRY--GYC-QQL 180
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS++C C PG+ ++ + C D++ECA + + CVNT GSF C C G EL
Sbjct: 181 CANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTYGSFICRCDPGYEL 238
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D + C D+DECS + +C + C NQ GTY C C GY
Sbjct: 239 EEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNH 297
Query: 296 RC--QHSCVNTPGSYHC 310
C Q +C N G + C
Sbjct: 298 TCNLQQTCYNLQGGFKC 314
Score = 124 bits (300), Expect = 6e-28
Identities = 83/263 (31%), Positives = 113/263 (42%), Gaps = 15/263 (5%)
Query: 117 MEVNECAAFPGLC-GHGRCRNLLGGFTCDCF--PGYEKDSKNHTCVDVNECEIVDGVCGD 173
++++EC P C G C N GG+ C P Y N +
Sbjct: 41 LDIDECRTIPEACRGDMMCVNQNGGYLCHSRTNPVYRGPYSNPYSTPYSGPYPAAAPPLS 100
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHG 232
+ T S CR GY+ D+ S CVD+DECA + C + C+N G + C C G
Sbjct: 101 APNYPTI-SRPLICRFGYQMDE-SNQCVDVDECATDSHQCNPTQICINMKGGYTCSCTDG 158
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
L + C DIDEC G C C N G+Y C C+ G+ +
Sbjct: 159 YWLLEGQ--CLDIDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNE-DGRSCQDVNECA 212
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
C +CVNT GS+ C C G+ L DG C D+DEC+ C +C N G+Y C
Sbjct: 213 TENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFC 271
Query: 353 TCTDGLVPSAAGAKPTCQDIDEC 375
+C G + +CQDI+EC
Sbjct: 272 SCPPGYI--LLDDNRSCQDINEC 292
Score = 117 bits (281), Expect = 1e-25
Identities = 59/164 (35%), Positives = 88/164 (53%), Gaps = 11/164 (6%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
++++EC G C C N+ G ++C C PG+ + +C DVNEC + C C
Sbjct: 167 LDIDECRY--GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC-ATENPCVQ-TC 221
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GSF C C PGY+ ++ C D+DEC+ ++ LC+ CVN G++ C C G L
Sbjct: 222 VNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQ-HECVNQPGTYFCSCPPGYILL 280
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCV----CDEGY 275
D SC+DI+EC + C+ C N G ++C+ C+E Y
Sbjct: 281 DDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPY 324
>X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane
protein protein.
Length = 835
Score = 143 bits (347), Expect = 1e-33
Identities = 87/232 (37%), Positives = 110/232 (47%), Gaps = 47/232 (20%)
Query: 300 SCVNTPGSYHCTCREGWH-----LRADGRSCRDIDECAGGAR-PCGG-GQCRNTVGSYTC 352
SCVN C C G+ + +C DI+ECA ++ CG C NT GSY C
Sbjct: 35 SCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDC 91
Query: 353 TCTDGLVPSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA- 404
C+ G P +GAK TCQD+DEC Q P LC +
Sbjct: 92 VCSPGYEP-VSGAKTFKNESENTCQDVDECQ--------------------QNPRLCKSY 130
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
G+C NT+GS+ CQC G+ PE CTD +EC G CH + C+N GS+QCRCR
Sbjct: 131 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 190
Query: 465 GWR--------GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
GW+ + CEDVDEC + C C NT GS+ C C G+K
Sbjct: 191 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242
Score = 126 bits (303), Expect = 3e-28
Identities = 77/204 (37%), Positives = 96/204 (47%), Gaps = 28/204 (13%)
Query: 143 CDCFPGYEKDSK-----NHTCVDVNECEIVDGV-CGD-GDCHNTEGSFTCHCRPGYK--- 192
C C PG+ S+ TC D+NEC V CG DC NTEGS+ C C PGY+
Sbjct: 42 CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 101
Query: 193 -----ADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELAP-DRLSCKDI 245
++ C D+DEC N LC+ G CVNT GS+ C+C G + P D C D+
Sbjct: 102 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV 161
Query: 246 DECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC---QHS- 300
+EC+ C S+ C N +G+YQC C G+ Q S C QH
Sbjct: 162 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGW-QPIPGSPNGPNNTVCEDVDECSSGQHQC 220
Query: 301 -----CVNTPGSYHCTCREGWHLR 319
C NT GSY C CR GW R
Sbjct: 221 DSSTVCFNTVGSYSCRCRPGWKPR 244
Score = 117 bits (282), Expect = 1e-25
Identities = 64/178 (35%), Positives = 90/178 (50%), Gaps = 20/178 (11%)
Query: 118 EVNECAAFPGL-CGH-GRCRNLLGGFTCDCFPGYE--------KDSKNHTCVDVNECEIV 167
++NECA + CG C N G + C C PGYE K+ +TC DV+EC+
Sbjct: 64 DINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 123
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYK-ADDFSKICVDIDECADNDALCRGG-RCVNTAGS 224
+C G C NT GS+TC C PG+K + K+C D++EC C C+N GS
Sbjct: 124 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 183
Query: 225 FRCECGHGME------LAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGY 275
++C C G + P+ C+D+DECS C S+ C N +G+Y C C G+
Sbjct: 184 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241
Score = 105 bits (251), Expect = 6e-22
Identities = 68/204 (33%), Positives = 86/204 (42%), Gaps = 30/204 (14%)
Query: 185 CHCRPGYKADDFSKI-------CVDIDECADNDALCRG--GRCVNTAGSFRCECGHGMEL 235
C C PG+ + FS+I C DI+ECA + G C NT GS+ C C G E
Sbjct: 42 CRCNPGFSS--FSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEP 99
Query: 236 AP--------DRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
+C+D+DEC +C S G C N +G+Y C C G+
Sbjct: 100 VSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCT 159
Query: 287 XXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHL------RADGRSCRDIDECAGGARP 337
HS C+N GSY C CR GW + C D+DEC+ G
Sbjct: 160 DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQ 219
Query: 338 CGGGQ-CRNTVGSYTCTCTDGLVP 360
C C NTVGSY+C C G P
Sbjct: 220 CDSSTVCFNTVGSYSCRCRPGWKP 243
Score = 101 bits (243), Expect = 5e-21
Identities = 58/170 (34%), Positives = 78/170 (45%), Gaps = 19/170 (11%)
Query: 402 CGAGS-CHNTIGSFVCQCPDGY-------SVKPEQGPACTDDDECELGTCDCHPAADCIN 453
CG S C NT GS+ C C GY + K E C D DEC+ C C+N
Sbjct: 76 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 135
Query: 454 LPGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK-- 508
GS+ C+C G++ D C DV+EC + CH C N GS++C C G++
Sbjct: 136 TLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPI 195
Query: 509 -GDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
G G C D+DEC++ C++ C NT G Y C C G+
Sbjct: 196 PGSPNGPNNTVCE----DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241
Score = 83.4 bits (197), Expect = 2e-15
Identities = 52/162 (32%), Positives = 71/162 (43%), Gaps = 22/162 (13%)
Query: 411 IGSFVCQCPDGYSVKPE----QGPACTDDDECELGT-CDCHPAADCINLPGSFQCRCRDG 465
+ + C+C G+S E C D +EC + C +DC N GS+ C C G
Sbjct: 37 VNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPG 96
Query: 466 WRG-DGA---------TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
+ GA TC+DVDEC N C TC NT GS+ C C G+K +
Sbjct: 97 YEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK 156
Query: 516 TVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVGF 556
C D++EC + C + HC N G Y+C C G+
Sbjct: 157 V------CTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 192
Score = 76.2 bits (179), Expect = 3e-13
Identities = 43/123 (34%), Positives = 61/123 (49%), Gaps = 15/123 (12%)
Query: 445 CHPAADCINLPGSFQCRCRDGWRGDGA-------TCEDVDECLT-NNGGCHPRATCANTD 496
C + C+N CRC G+ TC+D++EC T + C + C NT+
Sbjct: 30 CPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86
Query: 497 GSFRCLCDTGYKGDGYGLRTVC--CVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCD 553
GS+ C+C GY+ G +T +C D+DEC +P LC++ G C NT G Y C C
Sbjct: 87 GSYDCVCSPGYEPVS-GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCL 145
Query: 554 VGF 556
GF
Sbjct: 146 PGF 148
>AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane helix
receptor protein.
Length = 837
Score = 143 bits (347), Expect = 1e-33
Identities = 87/232 (37%), Positives = 110/232 (47%), Gaps = 47/232 (20%)
Query: 300 SCVNTPGSYHCTCREGWH-----LRADGRSCRDIDECAGGAR-PCGG-GQCRNTVGSYTC 352
SCVN C C G+ + +C DI+ECA ++ CG C NT GSY C
Sbjct: 37 SCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDC 93
Query: 353 TCTDGLVPSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA- 404
C+ G P +GAK TCQD+DEC Q P LC +
Sbjct: 94 VCSPGYEP-VSGAKTFKNESENTCQDVDECQ--------------------QNPRLCKSY 132
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
G+C NT+GS+ CQC G+ PE CTD +EC G CH + C+N GS+QCRCR
Sbjct: 133 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 192
Query: 465 GWR--------GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
GW+ + CEDVDEC + C C NT GS+ C C G+K
Sbjct: 193 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 244
Score = 126 bits (303), Expect = 3e-28
Identities = 77/204 (37%), Positives = 96/204 (47%), Gaps = 28/204 (13%)
Query: 143 CDCFPGYEKDSK-----NHTCVDVNECEIVDGV-CGD-GDCHNTEGSFTCHCRPGYK--- 192
C C PG+ S+ TC D+NEC V CG DC NTEGS+ C C PGY+
Sbjct: 44 CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 103
Query: 193 -----ADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELAP-DRLSCKDI 245
++ C D+DEC N LC+ G CVNT GS+ C+C G + P D C D+
Sbjct: 104 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV 163
Query: 246 DECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC---QHS- 300
+EC+ C S+ C N +G+YQC C G+ Q S C QH
Sbjct: 164 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGW-QPIPGSPNGPNNTVCEDVDECSSGQHQC 222
Query: 301 -----CVNTPGSYHCTCREGWHLR 319
C NT GSY C CR GW R
Sbjct: 223 DSSTVCFNTVGSYSCRCRPGWKPR 246
Score = 117 bits (282), Expect = 1e-25
Identities = 64/178 (35%), Positives = 90/178 (50%), Gaps = 20/178 (11%)
Query: 118 EVNECAAFPGL-CGH-GRCRNLLGGFTCDCFPGYE--------KDSKNHTCVDVNECEIV 167
++NECA + CG C N G + C C PGYE K+ +TC DV+EC+
Sbjct: 66 DINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 125
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYK-ADDFSKICVDIDECADNDALCRGG-RCVNTAGS 224
+C G C NT GS+TC C PG+K + K+C D++EC C C+N GS
Sbjct: 126 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 185
Query: 225 FRCECGHGME------LAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGY 275
++C C G + P+ C+D+DECS C S+ C N +G+Y C C G+
Sbjct: 186 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 243
Score = 105 bits (251), Expect = 6e-22
Identities = 68/204 (33%), Positives = 86/204 (42%), Gaps = 30/204 (14%)
Query: 185 CHCRPGYKADDFSKI-------CVDIDECADNDALCRG--GRCVNTAGSFRCECGHGMEL 235
C C PG+ + FS+I C DI+ECA + G C NT GS+ C C G E
Sbjct: 44 CRCNPGFSS--FSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEP 101
Query: 236 AP--------DRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
+C+D+DEC +C S G C N +G+Y C C G+
Sbjct: 102 VSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCT 161
Query: 287 XXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHL------RADGRSCRDIDECAGGARP 337
HS C+N GSY C CR GW + C D+DEC+ G
Sbjct: 162 DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQ 221
Query: 338 CGGGQ-CRNTVGSYTCTCTDGLVP 360
C C NTVGSY+C C G P
Sbjct: 222 CDSSTVCFNTVGSYSCRCRPGWKP 245
Score = 101 bits (243), Expect = 5e-21
Identities = 58/170 (34%), Positives = 78/170 (45%), Gaps = 19/170 (11%)
Query: 402 CGAGS-CHNTIGSFVCQCPDGY-------SVKPEQGPACTDDDECELGTCDCHPAADCIN 453
CG S C NT GS+ C C GY + K E C D DEC+ C C+N
Sbjct: 78 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 137
Query: 454 LPGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK-- 508
GS+ C+C G++ D C DV+EC + CH C N GS++C C G++
Sbjct: 138 TLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPI 197
Query: 509 -GDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
G G C D+DEC++ C++ C NT G Y C C G+
Sbjct: 198 PGSPNGPNNTVCE----DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 243
Score = 83.4 bits (197), Expect = 2e-15
Identities = 52/162 (32%), Positives = 71/162 (43%), Gaps = 22/162 (13%)
Query: 411 IGSFVCQCPDGYSVKPE----QGPACTDDDECELGT-CDCHPAADCINLPGSFQCRCRDG 465
+ + C+C G+S E C D +EC + C +DC N GS+ C C G
Sbjct: 39 VNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPG 98
Query: 466 WRG-DGA---------TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
+ GA TC+DVDEC N C TC NT GS+ C C G+K +
Sbjct: 99 YEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK 158
Query: 516 TVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVGF 556
C D++EC + C + HC N G Y+C C G+
Sbjct: 159 V------CTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 194
Score = 76.2 bits (179), Expect = 3e-13
Identities = 43/123 (34%), Positives = 61/123 (49%), Gaps = 15/123 (12%)
Query: 445 CHPAADCINLPGSFQCRCRDGWRGDGA-------TCEDVDECLT-NNGGCHPRATCANTD 496
C + C+N CRC G+ TC+D++EC T + C + C NT+
Sbjct: 32 CPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 88
Query: 497 GSFRCLCDTGYKGDGYGLRTVC--CVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCD 553
GS+ C+C GY+ G +T +C D+DEC +P LC++ G C NT G Y C C
Sbjct: 89 GSYDCVCSPGYEPVS-GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCL 147
Query: 554 VGF 556
GF
Sbjct: 148 PGF 150
>AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 142 bits (345), Expect = 2e-33
Identities = 136/480 (28%), Positives = 189/480 (39%), Gaps = 84/480 (17%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG 174
Q++VN+C P L C+NL+GG+ CDC PG+ K C ++VN+C G C G
Sbjct: 421 QLDVNDCEGKPCLNAFS-CKNLIGGYYCDCIPGW----KGINCHINVNDCR---GQCQHG 472
Query: 175 D-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C G+ ++ D+CA + GG C + A F C C G
Sbjct: 473 GTCKDLVNGYQCVCPRGFGGRHCE---LERDKCASSPCHS-GGLCEDLADGFHCHCPQGF 528
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVC--DEGYAQSTVK--------- 281
P L D+D C + C NGA C N G Y C C D G +V
Sbjct: 529 S-GP--LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGAC 583
Query: 282 -------SHXXXXXXXXXXXXRC-QHS-CVNTPG-SYHCTCREGWHLRADGRSCRD-IDE 330
S C H CV+ PG ++ C C G+ G C + ID+
Sbjct: 584 RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGF----TGTYCHENIDD 639
Query: 331 CAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPT------CQDIDECADLISTII 383
C G +PC GG C + V ++ C C G P C C DL++
Sbjct: 640 CLG--QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 697
Query: 384 MMSVDELQKSVDPQIPELCGA------GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
D + C A G+C+++ +F C CP G+ +G C
Sbjct: 698 CACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGW-----KGSTCAVAKN 752
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTNNGGCHPRATCANTD 496
C C+ SF C CRDGW +G TC + ++C N C+ C +
Sbjct: 753 SSCLPNPCVNGGTCVGSGASFSCICRDGW--EGRTCTHNTNDC--NPLPCYNGGICVDGV 808
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
FRC C G+ G C ++IDEC + P C G C + GY C C G
Sbjct: 809 NWFRCECAPGFAGPD------C----RINIDECQSSP--CAYGATCVDEINGYRCSCPPG 856
Score = 131 bits (317), Expect = 6e-30
Identities = 129/469 (27%), Positives = 183/469 (39%), Gaps = 101/469 (21%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGG-FTCDCFPGYEK---DSKNHTCVDVNECEIVDGVCGD 173
++N C + G C N + C C GY + H C N C
Sbjct: 307 DLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTS-NPC------ANG 359
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
G CH F CHC G+ +DIDECA N GG CV+ F C C
Sbjct: 360 GSCHEVPSGFECHCPSGWSG---PTCALDIDECASNPC-AAGGTCVDQVDGFECICPEQW 415
Query: 234 ELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A +L D+++C C N +C+N +G Y C C G+ + H
Sbjct: 416 VGATCQL---DVNDCE--GKPCLNAFSCKNLIGGYYCDCIPGW--KGINCH----INVND 464
Query: 293 XXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVG 348
+CQH +C + Y C C G+ GR C + D+CA + PC GG C +
Sbjct: 465 CRGQCQHGGTCKDLVNGYQCVCPRGF----GGRHCELERDKCA--SSPCHSGGLCEDLAD 518
Query: 349 SYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS- 406
+ C C G + P C+ D+D C P C G+
Sbjct: 519 GFHCHCPQGF------SGPLCEVDVDLCE----------------------PSPCRNGAR 550
Query: 407 CHNTIGSFVCQCPDGYSVK-------PEQGPACTDDDECEL-------GTCD---CHPAA 449
C+N G + C CPD + K P G AC D C GT C P
Sbjct: 551 CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHG 610
Query: 450 DCINLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
C++ P G+F C C G+ G E++D+CL C TC + +FRC C +G++
Sbjct: 611 RCVSQPGGNFSCICDSGFTGTYCH-ENIDDCL--GQPCRNGGTCIDEVDAFRCFCPSGWE 667
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
G+ +C + ++C DP C + G C + + C CD G+
Sbjct: 668 GE------LC----DTNPNDCLPDP--CHSRGRCYDLVNDFYCACDDGW 704
Score = 126 bits (303), Expect = 3e-28
Identities = 118/460 (25%), Positives = 185/460 (40%), Gaps = 68/460 (14%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG- 174
++++ECA+ P G G C + + GF C C + TC +DVN+CE C +
Sbjct: 384 LDIDECASNPCAAG-GTCVDQVDGFECIC----PEQWVGATCQLDVNDCE--GKPCLNAF 436
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGM 233
C N G + C C PG+K + +++++C C+ GG C + ++C C G
Sbjct: 437 SCKNLIGGYYCDCIPGWKGINCH---INVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGF 490
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L + D+C+ +S S G CE+ + C C +G++ +
Sbjct: 491 GGRHCEL---ERDKCA-SSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---VDVDLCEPS 543
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
R C N G Y+C C + + G++C E PC GG CR G C
Sbjct: 544 PCRNGARCYNLEGDYYCACPDDF----GGKNCSVPRE------PCPGGACRVIDG---CG 590
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDE------LQKSVDPQIPELC-GAGS 406
G A C C D +++D + + C G+
Sbjct: 591 SDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 650
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C + + +F C CP G+ +G C T+ ++C C H C +L F C C DG
Sbjct: 651 CIDEVDAFRCFCPSGW-----EGELCDTNPNDCLPDPC--HSRGRCYDLVNDFYCACDDG 703
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
W+ G TC E + C TC ++ +FRC C G+KG + C V
Sbjct: 704 WK--GKTCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKG------STCAV---AK 751
Query: 526 IDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C +P + G C + + C C G+ +GR+C
Sbjct: 752 NSSCLPNPCV-NGGTCVGSGASFSCICRDGW----EGRTC 786
Score = 117 bits (281), Expect = 1e-25
Identities = 110/432 (25%), Positives = 172/432 (39%), Gaps = 71/432 (16%)
Query: 117 MEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
+ VN+C G C HG C++L+ G+ C C G+ H ++ ++C C G
Sbjct: 460 INVNDCR---GQCQHGGTCKDLVNGYQCVCPRGF---GGRHCELERDKC--ASSPCHSGG 511
Query: 176 -CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGG-RCVNTAGSFRCECGH- 231
C + F CHC G+ +C VD+D C + CR G RC N G + C C
Sbjct: 512 LCEDLADGFHCHCPQGFSGP----LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDD 565
Query: 232 --GMELAPDRL-----SCKDIDEC----------SITSGICS-NGACENQMG-TYQCVCD 272
G + R +C+ ID C + SG+C +G C +Q G + C+CD
Sbjct: 566 FGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICD 625
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDEC 331
G+ + + R +C++ ++ C C GW +G C + ++C
Sbjct: 626 SGFTGTYCHENIDDCLGQPC---RNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDC 678
Query: 332 AGGARPCGG-GQCRNTVGSYTCTCTDGLVPSAAGAKP------TCQDIDECADLISTIIM 384
PC G+C + V + C C DG ++ TC + C D T
Sbjct: 679 LPD--PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC 736
Query: 385 MSVDELQKSV------DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
+ S +P C G+C + SF C C DG+ +G CT +
Sbjct: 737 ACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGW-----EGRTCTHNTN 791
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDG 497
+ C+ C++ F+C C G+ G ++DEC + C ATC +
Sbjct: 792 -DCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRI-NIDEC--QSSPCAYGATCVDEIN 847
Query: 498 SFRCLCDTGYKG 509
+RC C G G
Sbjct: 848 GYRCSCPPGRAG 859
Score = 88.6 bits (210), Expect = 5e-17
Identities = 80/280 (28%), Positives = 116/280 (41%), Gaps = 49/280 (17%)
Query: 301 CVNTPGSYHCTCREGWHLRAD----GRSC-RDIDECAGGARPC-GGGQCRNT-VGSYTCT 353
CV PG H +C E W + G C +D++ C G PC GG C N Y CT
Sbjct: 276 CVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYC-GSHHPCTNGGTCINAEPDQYRCT 334
Query: 354 CTDGL-------VPSAAGAKPTCQDIDECADLISTIIM-----MSVDELQKSVDPQIPEL 401
C DG A + P C + C ++ S S +D
Sbjct: 335 CPDGYSGRNCEKAEHACTSNP-CANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNP 393
Query: 402 CGA-GSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQ 459
C A G+C + + F C CP+ + G C D ++CE G C A C NL G +
Sbjct: 394 CAAGGTCVDQVDGFECICPEQW-----VGATCQLDVNDCE-GK-PCLNAFSCKNLIGGYY 446
Query: 460 CRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C C GW+ G C +V++C G C TC + ++C+C G+ G
Sbjct: 447 CDCIPGWK--GINCHINVNDC---RGQCQHGGTCKDLVNGYQCVCPRGFGGR-------- 493
Query: 519 CVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
+ ++ D+CA+ P C +G C + G+ C C GF+
Sbjct: 494 --HCELERDKCASSP--CHSGGLCEDLADGFHCHCPQGFS 529
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/253 (27%), Positives = 99/253 (39%), Gaps = 38/253 (15%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGG-----QCRNTVGSYTCTCTDGLVPSAAGAK 366
C +GW G+ C++ C G GG +CR + G C D VP
Sbjct: 231 CMDGWM----GKECKEA-VCKQGCNLLHGGCTVPGECRCSYGWQGRFC-DECVPYPGCVH 284
Query: 367 PTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI-GSFVCQCPDGYSVK 425
+C + +C + ++ +L G+C N + C CPDGYS
Sbjct: 285 GSCVEPWQCNCETNWGGLLCDKDLNYCGSHH--PCTNGGTCINAEPDQYRCTCPDGYS-- 340
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNG 484
G C + E + C C +P F+C C GW G TC D+DEC +N
Sbjct: 341 ---GRNC-EKAEHACTSNPCANGGSCHEVPSGFECHCPSGW--SGPTCALDIDECASN-- 392
Query: 485 GCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSN 543
C TC + F C+C + G C +D+++C P C N C N
Sbjct: 393 PCAAGGTCVDQVDGFECICPEQWVG------ATC----QLDVNDCEGKP--CLNAFSCKN 440
Query: 544 TPGGYECDCDVGF 556
GGY CDC G+
Sbjct: 441 LIGGYYCDCIPGW 453
Score = 50.4 bits (115), Expect = 2e-05
Identities = 35/120 (29%), Positives = 50/120 (41%), Gaps = 19/120 (15%)
Query: 443 CD-CHPAADCIN--LPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTD-G 497
CD C P C++ +QC C W G C+ D++ C +++ C TC N +
Sbjct: 273 CDECVPYPGCVHGSCVEPWQCNCETNW--GGLLCDKDLNYCGSHHP-CTNGGTCINAEPD 329
Query: 498 SFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
+RC C GY G C + CAN G C P G+EC C G++
Sbjct: 330 QYRCTCPDGYSGRNCEKAEHACTSN-----PCAN------GGSCHEVPSGFECHCPSGWS 378
>BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like 2 protein.
Length = 823
Score = 142 bits (344), Expect = 3e-33
Identities = 87/232 (37%), Positives = 110/232 (47%), Gaps = 47/232 (20%)
Query: 300 SCVNTPGSYHCTCREGWH-----LRADGRSCRDIDECAGGAR-PCGG-GQCRNTVGSYTC 352
SCVN C C G+ + +C DI+ECA ++ CG C NT GSY C
Sbjct: 38 SCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDC 94
Query: 353 TCTDGLVPSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA- 404
C+ G P +GAK TCQD+DEC Q P LC +
Sbjct: 95 VCSPGYEP-VSGAKTFKNESENTCQDVDECQ--------------------QNPRLCKSY 133
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
G+C NT+GS+ CQC G+ PE CTD +EC G CH + C+N GS+QCRCR
Sbjct: 134 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 193
Query: 465 GWR--------GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
GW+ + CEDVDEC + C C NT GS+ C C G+K
Sbjct: 194 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 126 bits (304), Expect = 2e-28
Identities = 77/204 (37%), Positives = 97/204 (47%), Gaps = 28/204 (13%)
Query: 143 CDCFPGYEKDSK-----NHTCVDVNECEIVDGV-CGD-GDCHNTEGSFTCHCRPGYK--- 192
C C PG+ S+ TC D+NEC + V CG DC NTEGS+ C C PGY+
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 193 -----ADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELAP-DRLSCKDI 245
++ C D+DEC N LC+ G CVNT GS+ C+C G + P D C D+
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV 164
Query: 246 DECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC---QHS- 300
+EC+ C S+ C N +G+YQC C G+ Q S C QH
Sbjct: 165 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGW-QPIPGSPNGPNNTVCEDVDECSSGQHQC 223
Query: 301 -----CVNTPGSYHCTCREGWHLR 319
C NT GSY C CR GW R
Sbjct: 224 DSSTVCFNTVGSYSCRCRPGWKPR 247
Score = 119 bits (286), Expect = 3e-26
Identities = 64/178 (35%), Positives = 90/178 (50%), Gaps = 20/178 (11%)
Query: 118 EVNECAAFPGL-CGH-GRCRNLLGGFTCDCFPGYE--------KDSKNHTCVDVNECEIV 167
++NECA + CG C N G + C C PGYE K+ +TC DV+EC+
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYK-ADDFSKICVDIDECADNDALCRGG-RCVNTAGS 224
+C G C NT GS+TC C PG+K + K+C D++EC C C+N GS
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 225 FRCECGHGME------LAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGY 275
++C C G + P+ C+D+DECS C S+ C N +G+Y C C G+
Sbjct: 187 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 105 bits (252), Expect = 4e-22
Identities = 71/216 (32%), Positives = 89/216 (41%), Gaps = 33/216 (15%)
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKI-------CVDIDECADNDALCRG--GRCVNTAG 223
D C N C C PG+ + FS+I C DI+ECA + G C NT G
Sbjct: 36 DSSCVNATA---CRCNPGFSS--FSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEG 90
Query: 224 SFRCECGHGMELAP--------DRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEG 274
S+ C C G E +C+D+DEC +C S G C N +G+Y C C G
Sbjct: 91 SYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG 150
Query: 275 YAQSTVKSHXXXXXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHL------RADGRSC 325
+ HS C+N GSY C CR GW + C
Sbjct: 151 FKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 210
Query: 326 RDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVP 360
D+DEC+ G C C NTVGSY+C C G P
Sbjct: 211 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Score = 102 bits (245), Expect = 3e-21
Identities = 78/248 (31%), Positives = 105/248 (42%), Gaps = 43/248 (17%)
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP-SAAGAKP--TCQDIDECADLISTII 383
+ + G AR C Q + V + C C G S P TC DI+ECA T+
Sbjct: 22 ETQDSRGCARWCP--QDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECA----TLS 75
Query: 384 MMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGY-------SVKPEQGPACTDD 435
+S CG S C NT GS+ C C GY + K E C D
Sbjct: 76 KVS---------------CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATC 492
DEC+ C C+N GS+ C+C G++ D C DV+EC + CH C
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 180
Query: 493 ANTDGSFRCLCDTGYK---GDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGY 548
N GS++C C G++ G G C D+DEC++ C++ C NT G Y
Sbjct: 181 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCE----DVDECSSGQHQCDSSTVCFNTVGSY 236
Query: 549 ECDCDVGF 556
C C G+
Sbjct: 237 SCRCRPGW 244
>BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like 2 protein.
Length = 823
Score = 142 bits (344), Expect = 3e-33
Identities = 87/232 (37%), Positives = 110/232 (47%), Gaps = 47/232 (20%)
Query: 300 SCVNTPGSYHCTCREGWH-----LRADGRSCRDIDECAGGAR-PCGG-GQCRNTVGSYTC 352
SCVN C C G+ + +C DI+ECA ++ CG C NT GSY C
Sbjct: 38 SCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDC 94
Query: 353 TCTDGLVPSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA- 404
C+ G P +GAK TCQD+DEC Q P LC +
Sbjct: 95 VCSPGYEP-VSGAKTFKNESENTCQDVDECQ--------------------QNPRLCKSY 133
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
G+C NT+GS+ CQC G+ PE CTD +EC G CH + C+N GS+QCRCR
Sbjct: 134 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 193
Query: 465 GWR--------GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
GW+ + CEDVDEC + C C NT GS+ C C G+K
Sbjct: 194 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 126 bits (304), Expect = 2e-28
Identities = 77/204 (37%), Positives = 97/204 (47%), Gaps = 28/204 (13%)
Query: 143 CDCFPGYEKDSK-----NHTCVDVNECEIVDGV-CGD-GDCHNTEGSFTCHCRPGYK--- 192
C C PG+ S+ TC D+NEC + V CG DC NTEGS+ C C PGY+
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 193 -----ADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELAP-DRLSCKDI 245
++ C D+DEC N LC+ G CVNT GS+ C+C G + P D C D+
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV 164
Query: 246 DECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC---QHS- 300
+EC+ C S+ C N +G+YQC C G+ Q S C QH
Sbjct: 165 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGW-QPIPGSPNGPNNTVCEDVDECSSGQHQC 223
Query: 301 -----CVNTPGSYHCTCREGWHLR 319
C NT GSY C CR GW R
Sbjct: 224 DSSTVCFNTVGSYSCRCRPGWKPR 247
Score = 119 bits (286), Expect = 3e-26
Identities = 64/178 (35%), Positives = 90/178 (50%), Gaps = 20/178 (11%)
Query: 118 EVNECAAFPGL-CGH-GRCRNLLGGFTCDCFPGYE--------KDSKNHTCVDVNECEIV 167
++NECA + CG C N G + C C PGYE K+ +TC DV+EC+
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYK-ADDFSKICVDIDECADNDALCRGG-RCVNTAGS 224
+C G C NT GS+TC C PG+K + K+C D++EC C C+N GS
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 225 FRCECGHGME------LAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGY 275
++C C G + P+ C+D+DECS C S+ C N +G+Y C C G+
Sbjct: 187 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 105 bits (252), Expect = 4e-22
Identities = 71/216 (32%), Positives = 89/216 (41%), Gaps = 33/216 (15%)
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKI-------CVDIDECADNDALCRG--GRCVNTAG 223
D C N C C PG+ + FS+I C DI+ECA + G C NT G
Sbjct: 36 DSSCVNATA---CRCNPGFSS--FSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEG 90
Query: 224 SFRCECGHGMELAP--------DRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEG 274
S+ C C G E +C+D+DEC +C S G C N +G+Y C C G
Sbjct: 91 SYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG 150
Query: 275 YAQSTVKSHXXXXXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHL------RADGRSC 325
+ HS C+N GSY C CR GW + C
Sbjct: 151 FKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 210
Query: 326 RDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVP 360
D+DEC+ G C C NTVGSY+C C G P
Sbjct: 211 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Score = 102 bits (245), Expect = 3e-21
Identities = 78/248 (31%), Positives = 105/248 (42%), Gaps = 43/248 (17%)
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP-SAAGAKP--TCQDIDECADLISTII 383
+ + G AR C Q + V + C C G S P TC DI+ECA T+
Sbjct: 22 ETQDSRGCARWCP--QDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECA----TLS 75
Query: 384 MMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGY-------SVKPEQGPACTDD 435
+S CG S C NT GS+ C C GY + K E C D
Sbjct: 76 KVS---------------CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATC 492
DEC+ C C+N GS+ C+C G++ D C DV+EC + CH C
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 180
Query: 493 ANTDGSFRCLCDTGYK---GDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGY 548
N GS++C C G++ G G C D+DEC++ C++ C NT G Y
Sbjct: 181 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCE----DVDECSSGQHQCDSSTVCFNTVGSY 236
Query: 549 ECDCDVGF 556
C C G+
Sbjct: 237 SCRCRPGW 244
>AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 142 bits (344), Expect = 3e-33
Identities = 136/480 (28%), Positives = 188/480 (39%), Gaps = 84/480 (17%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG 174
Q++ NEC P L C+NL+GG+ CDC PG+ K C ++VN+C G C G
Sbjct: 421 QLDANECEGKPCLNAFS-CKNLIGGYYCDCIPGW----KGINCHINVNDCR---GQCQHG 472
Query: 175 D-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C G+ ++ D+CA + GG C + A F C C G
Sbjct: 473 GTCKDLVNGYQCVCPRGFGGRHCE---LERDKCASSPCHS-GGLCEDLADGFHCHCPQGF 528
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVC--DEGYAQSTVK--------- 281
P L D+D C + C NGA C N G Y C C D G +V
Sbjct: 529 S-GP--LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGAC 583
Query: 282 -------SHXXXXXXXXXXXXRC-QHS-CVNTPG-SYHCTCREGWHLRADGRSCRD-IDE 330
S C H CV+ PG ++ C C G+ G C + ID+
Sbjct: 584 RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGF----TGTYCHENIDD 639
Query: 331 CAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPT------CQDIDECADLISTII 383
C G +PC GG C + V ++ C C G P C C DL++
Sbjct: 640 CLG--QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 697
Query: 384 MMSVDELQKSVDPQIPELCGA------GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
D + C A G+C+++ +F C CP G+ +G C
Sbjct: 698 CACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGW-----KGSTCAVAKN 752
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTNNGGCHPRATCANTD 496
C C+ SF C CRDGW +G TC + ++C N C+ C +
Sbjct: 753 SSCLPNPCVNGGTCVGSGASFSCICRDGW--EGRTCTHNTNDC--NPLPCYNGGICVDGV 808
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
FRC C G+ G C ++IDEC + P C G C + GY C C G
Sbjct: 809 NWFRCECAPGFAGPD------C----RINIDECQSSP--CAYGATCVDEINGYRCSCPPG 856
Score = 131 bits (316), Expect = 7e-30
Identities = 130/469 (27%), Positives = 182/469 (38%), Gaps = 101/469 (21%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGG-FTCDCFPGYEK---DSKNHTCVDVNECEIVDGVCGD 173
++N C + G C N + C C GY + H C N C
Sbjct: 307 DLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTS-NPC------ANG 359
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
G CH F CHC G+ +DIDECA N GG CV+ F C C
Sbjct: 360 GSCHEVPSGFECHCPSGWSG---PTCALDIDECASNPC-AAGGTCVDQVDGFECICPEQW 415
Query: 234 ELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A +L D +EC C N +C+N +G Y C C G+ + H
Sbjct: 416 VGATCQL---DANECE--GKPCLNAFSCKNLIGGYYCDCIPGW--KGINCH----INVND 464
Query: 293 XXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVG 348
+CQH +C + Y C C G+ GR C + D+CA + PC GG C +
Sbjct: 465 CRGQCQHGGTCKDLVNGYQCVCPRGF----GGRHCELERDKCA--SSPCHSGGLCEDLAD 518
Query: 349 SYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS- 406
+ C C G + P C+ D+D C P C G+
Sbjct: 519 GFHCHCPQGF------SGPLCEVDVDLCE----------------------PSPCRNGAR 550
Query: 407 CHNTIGSFVCQCPDGYSVK-------PEQGPACTDDDECEL-------GTCD---CHPAA 449
C+N G + C CPD + K P G AC D C GT C P
Sbjct: 551 CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHG 610
Query: 450 DCINLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
C++ P G+F C C G+ G E++D+CL C TC + +FRC C +G++
Sbjct: 611 RCVSQPGGNFSCICDSGFTGTYCH-ENIDDCL--GQPCRNGGTCIDEVDAFRCFCPSGWE 667
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
G+ +C + ++C DP C + G C + + C CD G+
Sbjct: 668 GE------LC----DTNPNDCLPDP--CHSRGRCYDLVNDFYCACDDGW 704
Score = 125 bits (302), Expect = 4e-28
Identities = 118/460 (25%), Positives = 184/460 (40%), Gaps = 68/460 (14%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG- 174
++++ECA+ P G G C + + GF C C + TC +D NECE C +
Sbjct: 384 LDIDECASNPCAAG-GTCVDQVDGFECIC----PEQWVGATCQLDANECE--GKPCLNAF 436
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGM 233
C N G + C C PG+K + +++++C C+ GG C + ++C C G
Sbjct: 437 SCKNLIGGYYCDCIPGWKGINCH---INVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGF 490
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L + D+C+ +S S G CE+ + C C +G++ +
Sbjct: 491 GGRHCEL---ERDKCA-SSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---VDVDLCEPS 543
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
R C N G Y+C C + + G++C E PC GG CR G C
Sbjct: 544 PCRNGARCYNLEGDYYCACPDDF----GGKNCSVPRE------PCPGGACRVIDG---CG 590
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDE------LQKSVDPQIPELC-GAGS 406
G A C C D +++D + + C G+
Sbjct: 591 SDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 650
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C + + +F C CP G+ +G C T+ ++C C H C +L F C C DG
Sbjct: 651 CIDEVDAFRCFCPSGW-----EGELCDTNPNDCLPDPC--HSRGRCYDLVNDFYCACDDG 703
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
W+ G TC E + C TC ++ +FRC C G+KG + C V
Sbjct: 704 WK--GKTCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKG------STCAV---AK 751
Query: 526 IDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C +P + G C + + C C G+ +GR+C
Sbjct: 752 NSSCLPNPCV-NGGTCVGSGASFSCICRDGW----EGRTC 786
Score = 117 bits (281), Expect = 1e-25
Identities = 110/432 (25%), Positives = 172/432 (39%), Gaps = 71/432 (16%)
Query: 117 MEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
+ VN+C G C HG C++L+ G+ C C G+ H ++ ++C C G
Sbjct: 460 INVNDCR---GQCQHGGTCKDLVNGYQCVCPRGF---GGRHCELERDKC--ASSPCHSGG 511
Query: 176 -CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGG-RCVNTAGSFRCECGH- 231
C + F CHC G+ +C VD+D C + CR G RC N G + C C
Sbjct: 512 LCEDLADGFHCHCPQGFSGP----LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDD 565
Query: 232 --GMELAPDRL-----SCKDIDEC----------SITSGICS-NGACENQMG-TYQCVCD 272
G + R +C+ ID C + SG+C +G C +Q G + C+CD
Sbjct: 566 FGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICD 625
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDEC 331
G+ + + R +C++ ++ C C GW +G C + ++C
Sbjct: 626 SGFTGTYCHENIDDCLGQPC---RNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDC 678
Query: 332 AGGARPCGG-GQCRNTVGSYTCTCTDGLVPSAAGAKP------TCQDIDECADLISTIIM 384
PC G+C + V + C C DG ++ TC + C D T
Sbjct: 679 LPD--PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC 736
Query: 385 MSVDELQKSV------DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
+ S +P C G+C + SF C C DG+ +G CT +
Sbjct: 737 ACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGW-----EGRTCTHNTN 791
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDG 497
+ C+ C++ F+C C G+ G ++DEC + C ATC +
Sbjct: 792 -DCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRI-NIDEC--QSSPCAYGATCVDEIN 847
Query: 498 SFRCLCDTGYKG 509
+RC C G G
Sbjct: 848 GYRCSCPPGRAG 859
Score = 90.2 bits (214), Expect = 2e-17
Identities = 81/280 (28%), Positives = 116/280 (41%), Gaps = 49/280 (17%)
Query: 301 CVNTPGSYHCTCREGWHLRAD----GRSC-RDIDECAGGARPC-GGGQCRNT-VGSYTCT 353
CV PG H +C E W + G C +D++ C G PC GG C N Y CT
Sbjct: 276 CVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYC-GSHHPCTNGGTCINAEPDQYRCT 334
Query: 354 CTDGL-------VPSAAGAKPTCQDIDECADLISTIIM-----MSVDELQKSVDPQIPEL 401
C DG A + P C + C ++ S S +D
Sbjct: 335 CPDGYSGRNCEKAEHACTSNP-CANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNP 393
Query: 402 CGA-GSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQ 459
C A G+C + + F C CP+ + G C D +ECE G C A C NL G +
Sbjct: 394 CAAGGTCVDQVDGFECICPEQW-----VGATCQLDANECE-GK-PCLNAFSCKNLIGGYY 446
Query: 460 CRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C C GW+ G C +V++C G C TC + ++C+C G+ G
Sbjct: 447 CDCIPGWK--GINCHINVNDC---RGQCQHGGTCKDLVNGYQCVCPRGFGGR-------- 493
Query: 519 CVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
+ ++ D+CA+ P C +G C + G+ C C GF+
Sbjct: 494 --HCELERDKCASSP--CHSGGLCEDLADGFHCHCPQGFS 529
Score = 76.2 bits (179), Expect = 3e-13
Identities = 71/253 (28%), Positives = 98/253 (38%), Gaps = 38/253 (15%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGG-----QCRNTVGSYTCTCTDGLVPSAAGAK 366
C +GW G+ C++ C G GG +CR + G C D VP
Sbjct: 231 CMDGWM----GKECKEA-VCKQGCNLLHGGCTVPGECRCSYGWQGRFC-DECVPYPGCVH 284
Query: 367 PTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI-GSFVCQCPDGYSVK 425
+C + +C + ++ +L G+C N + C CPDGYS
Sbjct: 285 GSCVEPWQCNCETNWGGLLCDKDLNYCGSHH--PCTNGGTCINAEPDQYRCTCPDGYS-- 340
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNG 484
G C + E + C C +P F+C C GW G TC D+DEC +N
Sbjct: 341 ---GRNC-EKAEHACTSNPCANGGSCHEVPSGFECHCPSGW--SGPTCALDIDECASN-- 392
Query: 485 GCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSN 543
C TC + F C+C + G C +D +EC P C N C N
Sbjct: 393 PCAAGGTCVDQVDGFECICPEQWVG------ATC----QLDANECEGKP--CLNAFSCKN 440
Query: 544 TPGGYECDCDVGF 556
GGY CDC G+
Sbjct: 441 LIGGYYCDCIPGW 453
Score = 50.4 bits (115), Expect = 2e-05
Identities = 35/120 (29%), Positives = 50/120 (41%), Gaps = 19/120 (15%)
Query: 443 CD-CHPAADCIN--LPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTD-G 497
CD C P C++ +QC C W G C+ D++ C +++ C TC N +
Sbjct: 273 CDECVPYPGCVHGSCVEPWQCNCETNW--GGLLCDKDLNYCGSHHP-CTNGGTCINAEPD 329
Query: 498 SFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
+RC C GY G C + CAN G C P G+EC C G++
Sbjct: 330 QYRCTCPDGYSGRNCEKAEHACTSN-----PCAN------GGSCHEVPSGFECHCPSGWS 378
>AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 142 bits (344), Expect = 3e-33
Identities = 136/480 (28%), Positives = 188/480 (39%), Gaps = 84/480 (17%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG 174
Q++ NEC P L C+NL+GG+ CDC PG+ K C ++VN+C G C G
Sbjct: 421 QLDANECEGKPCLNAFS-CKNLIGGYYCDCIPGW----KGINCHINVNDCR---GQCQHG 472
Query: 175 D-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C + + C C G+ ++ D+CA + GG C + A F C C G
Sbjct: 473 GTCKDLVNGYQCVCPRGFGGRHCE---LERDKCASSPCHS-GGLCEDLADGFHCHCPQGF 528
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVC--DEGYAQSTVK--------- 281
P L D+D C + C NGA C N G Y C C D G +V
Sbjct: 529 S-GP--LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGAC 583
Query: 282 -------SHXXXXXXXXXXXXRC-QHS-CVNTPG-SYHCTCREGWHLRADGRSCRD-IDE 330
S C H CV+ PG ++ C C G+ G C + ID+
Sbjct: 584 RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGF----TGTYCHENIDD 639
Query: 331 CAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPT------CQDIDECADLISTII 383
C G +PC GG C + V ++ C C G P C C DL++
Sbjct: 640 CLG--QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 697
Query: 384 MMSVDELQKSVDPQIPELCGA------GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
D + C A G+C+++ +F C CP G+ +G C
Sbjct: 698 CACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGW-----KGSTCAVAKN 752
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTNNGGCHPRATCANTD 496
C C+ SF C CRDGW +G TC + ++C N C+ C +
Sbjct: 753 SSCLPNPCVNGGTCVGSGASFSCICRDGW--EGRTCTHNTNDC--NPLPCYNGGICVDGV 808
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
FRC C G+ G C ++IDEC + P C G C + GY C C G
Sbjct: 809 NWFRCECAPGFAGPD------C----RINIDECQSSP--CAYGATCVDEINGYRCSCPPG 856
Score = 131 bits (316), Expect = 7e-30
Identities = 130/469 (27%), Positives = 182/469 (38%), Gaps = 101/469 (21%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGG-FTCDCFPGYEK---DSKNHTCVDVNECEIVDGVCGD 173
++N C + G C N + C C GY + H C N C
Sbjct: 307 DLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTS-NPC------ANG 359
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
G CH F CHC G+ +DIDECA N GG CV+ F C C
Sbjct: 360 GSCHEVPSGFECHCPSGWSG---PTCALDIDECASNPC-AAGGTCVDQVDGFECICPEQW 415
Query: 234 ELAPDRLSCKDIDECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
A +L D +EC C N +C+N +G Y C C G+ + H
Sbjct: 416 VGATCQL---DANECE--GKPCLNAFSCKNLIGGYYCDCIPGW--KGINCH----INVND 464
Query: 293 XXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVG 348
+CQH +C + Y C C G+ GR C + D+CA + PC GG C +
Sbjct: 465 CRGQCQHGGTCKDLVNGYQCVCPRGF----GGRHCELERDKCA--SSPCHSGGLCEDLAD 518
Query: 349 SYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS- 406
+ C C G + P C+ D+D C P C G+
Sbjct: 519 GFHCHCPQGF------SGPLCEVDVDLCE----------------------PSPCRNGAR 550
Query: 407 CHNTIGSFVCQCPDGYSVK-------PEQGPACTDDDECEL-------GTCD---CHPAA 449
C+N G + C CPD + K P G AC D C GT C P
Sbjct: 551 CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHG 610
Query: 450 DCINLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
C++ P G+F C C G+ G E++D+CL C TC + +FRC C +G++
Sbjct: 611 RCVSQPGGNFSCICDSGFTGTYCH-ENIDDCL--GQPCRNGGTCIDEVDAFRCFCPSGWE 667
Query: 509 GDGYGLRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
G+ +C + ++C DP C + G C + + C CD G+
Sbjct: 668 GE------LC----DTNPNDCLPDP--CHSRGRCYDLVNDFYCACDDGW 704
Score = 125 bits (302), Expect = 4e-28
Identities = 118/460 (25%), Positives = 184/460 (40%), Gaps = 68/460 (14%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDG- 174
++++ECA+ P G G C + + GF C C + TC +D NECE C +
Sbjct: 384 LDIDECASNPCAAG-GTCVDQVDGFECIC----PEQWVGATCQLDANECE--GKPCLNAF 436
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGM 233
C N G + C C PG+K + +++++C C+ GG C + ++C C G
Sbjct: 437 SCKNLIGGYYCDCIPGWKGINCH---INVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGF 490
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L + D+C+ +S S G CE+ + C C +G++ +
Sbjct: 491 GGRHCEL---ERDKCA-SSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---VDVDLCEPS 543
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
R C N G Y+C C + + G++C E PC GG CR G C
Sbjct: 544 PCRNGARCYNLEGDYYCACPDDF----GGKNCSVPRE------PCPGGACRVIDG---CG 590
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDE------LQKSVDPQIPELC-GAGS 406
G A C C D +++D + + C G+
Sbjct: 591 SDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 650
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C + + +F C CP G+ +G C T+ ++C C H C +L F C C DG
Sbjct: 651 CIDEVDAFRCFCPSGW-----EGELCDTNPNDCLPDPC--HSRGRCYDLVNDFYCACDDG 703
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
W+ G TC E + C TC ++ +FRC C G+KG + C V
Sbjct: 704 WK--GKTCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKG------STCAV---AK 751
Query: 526 IDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C +P + G C + + C C G+ +GR+C
Sbjct: 752 NSSCLPNPCV-NGGTCVGSGASFSCICRDGW----EGRTC 786
Score = 117 bits (281), Expect = 1e-25
Identities = 110/432 (25%), Positives = 172/432 (39%), Gaps = 71/432 (16%)
Query: 117 MEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
+ VN+C G C HG C++L+ G+ C C G+ H ++ ++C C G
Sbjct: 460 INVNDCR---GQCQHGGTCKDLVNGYQCVCPRGF---GGRHCELERDKC--ASSPCHSGG 511
Query: 176 -CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGG-RCVNTAGSFRCECGH- 231
C + F CHC G+ +C VD+D C + CR G RC N G + C C
Sbjct: 512 LCEDLADGFHCHCPQGFSGP----LCEVDVDLCEPSP--CRNGARCYNLEGDYYCACPDD 565
Query: 232 --GMELAPDRL-----SCKDIDEC----------SITSGICS-NGACENQMG-TYQCVCD 272
G + R +C+ ID C + SG+C +G C +Q G + C+CD
Sbjct: 566 FGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICD 625
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDEC 331
G+ + + R +C++ ++ C C GW +G C + ++C
Sbjct: 626 SGFTGTYCHENIDDCLGQPC---RNGGTCIDEVDAFRCFCPSGW----EGELCDTNPNDC 678
Query: 332 AGGARPCGG-GQCRNTVGSYTCTCTDGLVPSAAGAKP------TCQDIDECADLISTIIM 384
PC G+C + V + C C DG ++ TC + C D T
Sbjct: 679 LPD--PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC 736
Query: 385 MSVDELQKSV------DPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
+ S +P C G+C + SF C C DG+ +G CT +
Sbjct: 737 ACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGW-----EGRTCTHNTN 791
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDG 497
+ C+ C++ F+C C G+ G ++DEC + C ATC +
Sbjct: 792 -DCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRI-NIDEC--QSSPCAYGATCVDEIN 847
Query: 498 SFRCLCDTGYKG 509
+RC C G G
Sbjct: 848 GYRCSCPPGRAG 859
Score = 90.2 bits (214), Expect = 2e-17
Identities = 81/280 (28%), Positives = 116/280 (41%), Gaps = 49/280 (17%)
Query: 301 CVNTPGSYHCTCREGWHLRAD----GRSC-RDIDECAGGARPC-GGGQCRNT-VGSYTCT 353
CV PG H +C E W + G C +D++ C G PC GG C N Y CT
Sbjct: 276 CVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYC-GSHHPCTNGGTCINAEPDQYRCT 334
Query: 354 CTDGL-------VPSAAGAKPTCQDIDECADLISTIIM-----MSVDELQKSVDPQIPEL 401
C DG A + P C + C ++ S S +D
Sbjct: 335 CPDGYSGRNCEKAEHACTSNP-CANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNP 393
Query: 402 CGA-GSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQ 459
C A G+C + + F C CP+ + G C D +ECE G C A C NL G +
Sbjct: 394 CAAGGTCVDQVDGFECICPEQW-----VGATCQLDANECE-GK-PCLNAFSCKNLIGGYY 446
Query: 460 CRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C C GW+ G C +V++C G C TC + ++C+C G+ G
Sbjct: 447 CDCIPGWK--GINCHINVNDC---RGQCQHGGTCKDLVNGYQCVCPRGFGGR-------- 493
Query: 519 CVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFT 557
+ ++ D+CA+ P C +G C + G+ C C GF+
Sbjct: 494 --HCELERDKCASSP--CHSGGLCEDLADGFHCHCPQGFS 529
Score = 76.2 bits (179), Expect = 3e-13
Identities = 71/253 (28%), Positives = 98/253 (38%), Gaps = 38/253 (15%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGG-----QCRNTVGSYTCTCTDGLVPSAAGAK 366
C +GW G+ C++ C G GG +CR + G C D VP
Sbjct: 231 CMDGWM----GKECKEA-VCKQGCNLLHGGCTVPGECRCSYGWQGRFC-DECVPYPGCVH 284
Query: 367 PTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI-GSFVCQCPDGYSVK 425
+C + +C + ++ +L G+C N + C CPDGYS
Sbjct: 285 GSCVEPWQCNCETNWGGLLCDKDLNYCGSHH--PCTNGGTCINAEPDQYRCTCPDGYS-- 340
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNG 484
G C + E + C C +P F+C C GW G TC D+DEC +N
Sbjct: 341 ---GRNC-EKAEHACTSNPCANGGSCHEVPSGFECHCPSGW--SGPTCALDIDECASN-- 392
Query: 485 GCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENG-HCSN 543
C TC + F C+C + G C +D +EC P C N C N
Sbjct: 393 PCAAGGTCVDQVDGFECICPEQWVG------ATC----QLDANECEGKP--CLNAFSCKN 440
Query: 544 TPGGYECDCDVGF 556
GGY CDC G+
Sbjct: 441 LIGGYYCDCIPGW 453
Score = 50.4 bits (115), Expect = 2e-05
Identities = 35/120 (29%), Positives = 50/120 (41%), Gaps = 19/120 (15%)
Query: 443 CD-CHPAADCIN--LPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTD-G 497
CD C P C++ +QC C W G C+ D++ C +++ C TC N +
Sbjct: 273 CDECVPYPGCVHGSCVEPWQCNCETNW--GGLLCDKDLNYCGSHHP-CTNGGTCINAEPD 329
Query: 498 SFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
+RC C GY G C + CAN G C P G+EC C G++
Sbjct: 330 QYRCTCPDGYSGRNCEKAEHACTSN-----PCAN------GGSCHEVPSGFECHCPSGWS 378
>AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein.
Length = 502
Score = 142 bits (344), Expect = 3e-33
Identities = 119/407 (29%), Positives = 167/407 (41%), Gaps = 58/407 (14%)
Query: 126 PGLCG-HGRCRNLLGGFT-CDCFPGY--EKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
P C GRC G C C PG+ E+ C N C V+G G C T
Sbjct: 123 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-SANPC--VNG----GVCLATYP 175
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRL 240
CHC PG++ + D++EC + C +G C NT GSF+C C G E L
Sbjct: 176 QIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCEL 232
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH- 299
++G E + C+C G+ + + +CQ+
Sbjct: 233 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSH-----QCQNG 287
Query: 300 -SCVNTPGSYHCTCREGWHLRADGRSC-RDIDEC-AGGARPC-GGGQCRNTVGSYTCTCT 355
+C + +Y C C E W G C D+DEC A G C GG C+N+ GS+ C C
Sbjct: 288 GTCQDGLDTYTCLCPETW----TGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCV 343
Query: 356 DGLVPSAAGAK------PTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHN 409
G ++ TC C D + + + + + + ++C + CH
Sbjct: 344 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG-RTGLLCHLEDMCLSQPCHG 402
Query: 410 TI--------GSFVCQCPDGYSVKPEQGPACTDD-DEC---ELGTCDCHPAADCINLPGS 457
GS +C C GYS GP C D DEC + G C C+N PGS
Sbjct: 403 DAQCSTNPLTGSTLCLCQPGYS-----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGS 457
Query: 458 FQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLC 503
F C C G+ G + CE D +ECL+ CHP +TC + +F CLC
Sbjct: 458 FNCLCPPGYTG--SRCEADHNECLSQP--CHPGSTCLDLLATFHCLC 500
Score = 140 bits (340), Expect = 9e-33
Identities = 129/450 (28%), Positives = 177/450 (39%), Gaps = 82/450 (18%)
Query: 137 LLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDCH-NTEGSFTCHCRPGYKAD 194
L F C C PG+ + C E C G CH G C C PG+ +
Sbjct: 96 LTPSFLCTCLPGFTGER----CQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGE 151
Query: 195 DFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGI 254
C D C+ N + GG C+ T +C C G E +D++EC G
Sbjct: 152 Q----CQLRDFCSANPCV-NGGVCLATYPQIQCHCPPGFE---GHACERDVNECFQDPGP 203
Query: 255 CSNG-ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYH-CTC 312
C G +C N +G++QC+C G + ++H C C
Sbjct: 204 CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 263
Query: 313 REGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ 370
G+ G C + D C + C GG C++ + +YTC C P +
Sbjct: 264 PPGFI----GPGCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLC-----PETWTGWDCSE 312
Query: 371 DIDECADLISTIIMMSVDELQKSVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQG 429
D+DEC + Q P C G+C N+ GSF C C G+ G
Sbjct: 313 DVDEC-------------------EAQGPPHCRNGGTCQNSAGSFHCVCVSGWG-----G 348
Query: 430 PACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHP 488
+C ++ D+C TC P + CI+ GSF C C G G C D CL+ CH
Sbjct: 349 TSCEENLDDCIAATCA--PGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLSQP--CHG 402
Query: 489 RATCANTD--GSFRCLCDTGYKGDGYGLRTVCCVYSC-VDIDECA---NDPTLCENG-HC 541
A C+ GS CLC GY G +C D+DEC P+ CE+G C
Sbjct: 403 DAQCSTNPLTGSTLCLCQPGYSGP-----------TCHQDLDECLMAQQGPSPCEHGGSC 451
Query: 542 SNTPGGYECDCDVGFTRA---ADGRSCLGK 568
NTPG + C C G+T + AD CL +
Sbjct: 452 LNTPGSFNCLCPPGYTGSRCEADHNECLSQ 481
Score = 113 bits (273), Expect = 1e-24
Identities = 109/366 (29%), Positives = 147/366 (40%), Gaps = 75/366 (20%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ +VNEC PG C G C N LG F C C G E CE+ G C
Sbjct: 191 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGP----------RCELRAGPCPPR 240
Query: 175 DCHN---------TEGSF-TCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGS 224
C N + +F C C PG+ V+ D C + GG C + +
Sbjct: 241 GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCE---VNPDNCVSHQCQ-NGGTCQDGLDT 296
Query: 225 FRCECGHGMELAPDRLSCKDIDECSITS-GICSN-GACENQMGTYQCVCDEGYAQSTVKS 282
+ C C E +D+DEC C N G C+N G++ CVC G+ ++ +
Sbjct: 297 YTCLC---PETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE 353
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGG 341
+ +C++ GS+ C C G G C D C ++PC G
Sbjct: 354 NLDDCIAATCAPG---STCIDRVGSFSCLCPPG----RTGLLCHLEDMCL--SQPCHGDA 404
Query: 342 QCRNT--VGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDELQKSVDPQI 398
QC GS C C G + PTC QD+DEC +M+ Q
Sbjct: 405 QCSTNPLTGSTLCLCQPGY------SGPTCHQDLDEC--------LMA---------QQG 441
Query: 399 PELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPG 456
P C GSC NT GSF C CP GY+ G C D +EC + CHP + C++L
Sbjct: 442 PSPCEHGGSCLNTPGSFNCLCPPGYT-----GSRCEADHNECL--SQPCHPGSTCLDLLA 494
Query: 457 SFQCRC 462
+F C C
Sbjct: 495 TFHCLC 500
Score = 69.3 bits (162), Expect = 3e-11
Identities = 69/253 (27%), Positives = 97/253 (38%), Gaps = 34/253 (13%)
Query: 331 CAGGARPCG-GGQCRN-TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
C PC GG C + ++G TC C G + CQ+ C + S ++
Sbjct: 27 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 86
Query: 389 -ELQKSVDPQIPE-LCGAGSCHNTIGSFVCQ------CPDGY-------SVKPEQGPACT 433
L S P P LC +C CQ CP + ++ P C+
Sbjct: 87 LGLPSSPSPLTPSFLC---TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCS 143
Query: 434 -----DDDECEL-GTCDCHPAAD---CINLPGSFQCRCRDGWRGDGATCE-DVDECLTNN 483
++C+L C +P + C+ QC C G+ +G CE DV+EC +
Sbjct: 144 CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF--EGHACERDVNECFQDP 201
Query: 484 GGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT-VCCVYSCVDIDECANDPTLCENGH-C 541
G C +C NT GSF+CLC G +G LR C C + C P H C
Sbjct: 202 GPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLC 261
Query: 542 SNTPGGYECDCDV 554
PG C+V
Sbjct: 262 LCPPGFIGPGCEV 274
>U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein.
Length = 835
Score = 142 bits (343), Expect = 4e-33
Identities = 86/232 (37%), Positives = 109/232 (46%), Gaps = 47/232 (20%)
Query: 300 SCVNTPGSYHCTCREGWH-----LRADGRSCRDIDECAGGAR-PCGG-GQCRNTVGSYTC 352
SCVN C C G+ + +C DI+ECA ++ CG C NT GSY C
Sbjct: 35 SCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDC 91
Query: 353 TCTDGLVPSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA- 404
C+ G P +G K TCQD+DEC Q P LC +
Sbjct: 92 VCSPGYEP-VSGTKTFKNESENTCQDVDECQ--------------------QNPRLCKSY 130
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
G+C NT+GS+ CQC G+ PE CTD +EC G CH + C+N GS+QCRCR
Sbjct: 131 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 190
Query: 465 GWR--------GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
GW+ + CEDVDEC + C C NT GS+ C C G+K
Sbjct: 191 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242
Score = 126 bits (303), Expect = 3e-28
Identities = 77/204 (37%), Positives = 96/204 (47%), Gaps = 28/204 (13%)
Query: 143 CDCFPGYEKDSK-----NHTCVDVNECEIVDGV-CGD-GDCHNTEGSFTCHCRPGYK--- 192
C C PG+ S+ TC D+NEC V CG DC NTEGS+ C C PGY+
Sbjct: 42 CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 101
Query: 193 -----ADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELAP-DRLSCKDI 245
++ C D+DEC N LC+ G CVNT GS+ C+C G + P D C D+
Sbjct: 102 GTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV 161
Query: 246 DECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC---QHS- 300
+EC+ C S+ C N +G+YQC C G+ Q S C QH
Sbjct: 162 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGW-QPIPGSPNGPNNTVCEDVDECSSGQHQC 220
Query: 301 -----CVNTPGSYHCTCREGWHLR 319
C NT GSY C CR GW R
Sbjct: 221 DSSTVCFNTVGSYSCRCRPGWKPR 244
Score = 117 bits (282), Expect = 1e-25
Identities = 64/178 (35%), Positives = 90/178 (50%), Gaps = 20/178 (11%)
Query: 118 EVNECAAFPGL-CGH-GRCRNLLGGFTCDCFPGYE--------KDSKNHTCVDVNECEIV 167
++NECA + CG C N G + C C PGYE K+ +TC DV+EC+
Sbjct: 64 DINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQN 123
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYK-ADDFSKICVDIDECADNDALCRGG-RCVNTAGS 224
+C G C NT GS+TC C PG+K + K+C D++EC C C+N GS
Sbjct: 124 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 183
Query: 225 FRCECGHGME------LAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGY 275
++C C G + P+ C+D+DECS C S+ C N +G+Y C C G+
Sbjct: 184 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241
Score = 105 bits (251), Expect = 6e-22
Identities = 68/204 (33%), Positives = 86/204 (42%), Gaps = 30/204 (14%)
Query: 185 CHCRPGYKADDFSKI-------CVDIDECADNDALCRG--GRCVNTAGSFRCECGHGMEL 235
C C PG+ + FS+I C DI+ECA + G C NT GS+ C C G E
Sbjct: 42 CRCNPGFSS--FSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEP 99
Query: 236 AP--------DRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
+C+D+DEC +C S G C N +G+Y C C G+
Sbjct: 100 VSGTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCT 159
Query: 287 XXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHL------RADGRSCRDIDECAGGARP 337
HS C+N GSY C CR GW + C D+DEC+ G
Sbjct: 160 DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQ 219
Query: 338 CGGGQ-CRNTVGSYTCTCTDGLVP 360
C C NTVGSY+C C G P
Sbjct: 220 CDSSTVCFNTVGSYSCRCRPGWKP 243
Score = 101 bits (243), Expect = 5e-21
Identities = 58/170 (34%), Positives = 78/170 (45%), Gaps = 19/170 (11%)
Query: 402 CGAGS-CHNTIGSFVCQCPDGY-------SVKPEQGPACTDDDECELGTCDCHPAADCIN 453
CG S C NT GS+ C C GY + K E C D DEC+ C C+N
Sbjct: 76 CGKFSDCWNTEGSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 135
Query: 454 LPGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK-- 508
GS+ C+C G++ D C DV+EC + CH C N GS++C C G++
Sbjct: 136 TLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPI 195
Query: 509 -GDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
G G C D+DEC++ C++ C NT G Y C C G+
Sbjct: 196 PGSPNGPNNTVCE----DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241
Score = 81.8 bits (193), Expect = 6e-15
Identities = 50/162 (30%), Positives = 69/162 (42%), Gaps = 22/162 (13%)
Query: 411 IGSFVCQCPDGYSVKPE----QGPACTDDDECELGT-CDCHPAADCINLPGSFQCRCRDG 465
+ + C+C G+S E C D +EC + C +DC N GS+ C C G
Sbjct: 37 VNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPG 96
Query: 466 WRGDGAT----------CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
+ T C+DVDEC N C TC NT GS+ C C G+K +
Sbjct: 97 YEPVSGTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK 156
Query: 516 TVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVGF 556
C D++EC + C + HC N G Y+C C G+
Sbjct: 157 V------CTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 192
Score = 76.2 bits (179), Expect = 3e-13
Identities = 43/123 (34%), Positives = 61/123 (49%), Gaps = 15/123 (12%)
Query: 445 CHPAADCINLPGSFQCRCRDGWRGDGA-------TCEDVDECLT-NNGGCHPRATCANTD 496
C + C+N CRC G+ TC+D++EC T + C + C NT+
Sbjct: 30 CPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86
Query: 497 GSFRCLCDTGYKGDGYGLRTVC--CVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCD 553
GS+ C+C GY+ G +T +C D+DEC +P LC++ G C NT G Y C C
Sbjct: 87 GSYDCVCSPGYEPVS-GTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCL 145
Query: 554 VGF 556
GF
Sbjct: 146 PGF 148
>BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein.
Length = 347
Score = 140 bits (338), Expect = 2e-32
Identities = 101/302 (33%), Positives = 132/302 (43%), Gaps = 26/302 (8%)
Query: 159 VDVNEC-EIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG-- 215
VDV+EC E D D C NT S+ C C+PGYK + K C DIDEC +ND G
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGE--GKQCEDIDEC-ENDYYNGGCV 88
Query: 216 GRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+N G++RC C G LA D +C D+DEC +G C C N MG+Y+C C G+
Sbjct: 89 HECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGF 147
Query: 276 ----AQSTVKSHXXXXXXXXXXXXRCQHSCVNTP-GSYHCTCREGWHLRADGRSCRDIDE 330
Q T C H C TP G C CR G+ L + + C
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC--TLT 205
Query: 331 CAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
C G C C +T TC C + G TC + DE A S SV ++
Sbjct: 206 CNYGNGGC-QHSCEDTDTGPTCGCHQKYALHSDGR--TCIEKDEAAIERSQFNATSVADV 262
Query: 391 QKSVDPQ-IPELCGAG------SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTC 443
K V + + E C +C +T C CP G++++P+ G C EL C
Sbjct: 263 DKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPD-GKTC-KGQHVELCGC 320
Query: 444 DC 445
C
Sbjct: 321 PC 322
Score = 111 bits (267), Expect = 6e-24
Identities = 54/139 (38%), Positives = 76/139 (54%), Gaps = 12/139 (8%)
Query: 430 PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTN--NGGCH 487
P D DEC GT DCH A C N P S++C C+ G++G+G CED+DEC + NGGC
Sbjct: 29 PGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCV 88
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGG 547
C N G++RC C G+ G ++C+D+DEC ++ C+ C N G
Sbjct: 89 HE--CINIPGNYRCTCFDGFMLAHDG-------HNCLDVDECQDNNGGCQQ-ICVNAMGS 138
Query: 548 YECDCDVGFTRAADGRSCL 566
YEC C GF + + +C+
Sbjct: 139 YECQCHSGFFLSDNQHTCI 157
Score = 110 bits (265), Expect = 1e-23
Identities = 66/223 (29%), Positives = 103/223 (46%), Gaps = 13/223 (5%)
Query: 117 MEVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECE--IVDGVCGD 173
++V+EC+ C C+N + C C PGY+ + K C D++ECE +G C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQ--CEDIDECENDYYNGGCVH 89
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
+C N G++ C C G+ C+D+DEC DN+ C+ CVN GS+ C+C G
Sbjct: 90 -ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQ-QICVNAMGSYECQCHSGF 147
Query: 234 ELAPDRLSC----KDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
L+ ++ +C + C C++ E G C C G+ ++
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGF--DLAQNQKDCTLT 205
Query: 290 XXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECA 332
CQHSC +T C C + + L +DGR+C + DE A
Sbjct: 206 CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIEKDEAA 248
Score = 107 bits (257), Expect = 1e-22
Identities = 60/162 (37%), Positives = 79/162 (48%), Gaps = 12/162 (7%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C NT S+ C C GY +G C D DECE + +CIN+PG+++C C DG+
Sbjct: 50 CQNTPKSYKCLCKPGYK---GEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGF 106
Query: 467 R--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
DG C DVDEC NNGGC + C N GS+ C C +G+ C++
Sbjct: 107 MLAHDGHNCLDVDECQDNNGGC--QQICVNAMGSYECQCHSGFFLSD---NQHTCIHRSN 161
Query: 525 DIDECANDPTLCENGHCSNTP-GGYECDCDVGFTRAADGRSC 565
+ C N C + C TP GG CDC GF A + + C
Sbjct: 162 EGMNCMNKDHGCAH-ICRETPKGGVACDCRPGFDLAQNQKDC 202
Score = 96.7 bits (230), Expect = 2e-19
Identities = 88/291 (30%), Positives = 115/291 (39%), Gaps = 50/291 (17%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTCTDGLV 359
C NTP SY C C+ G+ + +G+ C DIDEC G +C N G+Y CTC DG +
Sbjct: 50 CQNTPKSYKCLCKPGY--KGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFM 107
Query: 360 PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCP 419
+ G C D+DEC D QI C N +GS+ CQC
Sbjct: 108 LAHDGHN--CLDVDECQD-------------NNGGCQQI--------CVNAMGSYECQCH 144
Query: 420 DGYSVKPEQGPACTDDDECELGTCDCHPAAD-CINLP-GSFQCRCRDGWRGDGATCEDVD 477
G+ + Q +E H A C P G C CR G+ +
Sbjct: 145 SGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTL 204
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYK--GDGYGL---------RTVCCVYSCVDI 526
C NGGC + +C +TD C C Y DG R+ S D+
Sbjct: 205 TCNYGNGGC--QHSCEDTDTGPTCGCHQKYALHSDGRTCIEKDEAAIERSQFNATSVADV 262
Query: 527 DECANDPTLCE-----NGHCS----NTPGGYECDCDVGFTRAADGRSCLGK 568
D+ L E NG C +T G C C VGFT DG++C G+
Sbjct: 263 DKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKGQ 313
>AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein.
Length = 320
Score = 138 bits (334), Expect = 5e-32
Identities = 75/195 (38%), Positives = 100/195 (51%), Gaps = 12/195 (6%)
Query: 119 VNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++EC A C + C NL G F C C PGY+K + CVD++EC I C C
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPP-YCHQR-CV 56
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAP 237
NT GSF C C PG++ + CVDI+EC D C +C N GSF C+C G EL+
Sbjct: 57 NTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQC-AQQCYNILGSFICQCNQGYELSS 114
Query: 238 DRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
DRL+C+DIDEC +S +C C N+ G + C+C +GY V+S C
Sbjct: 115 DRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGY--QVVRSRTCQDINECETTNEC 171
Query: 298 QHS--CVNTPGSYHC 310
+ C N G + C
Sbjct: 172 REDEMCWNYHGGFRC 186
Score = 132 bits (319), Expect = 3e-30
Identities = 87/263 (33%), Positives = 123/263 (46%), Gaps = 19/263 (7%)
Query: 161 VNECEIVDGVC-GDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCV 219
++EC C D C N GSF C C PGY+ + CVDIDEC C RCV
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDECTI-PPYCHQ-RCV 56
Query: 220 NTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQST 279
NT GSF C+C G +LA + +C DI+EC S C+ C N +G++ C C++GY S+
Sbjct: 57 NTPGSFYCQCSPGFQLAANNYTCVDINECD-ASNQCAQ-QCYNILGSFICQCNQGYELSS 114
Query: 280 VKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
+ + CQ+ CVN PG + C C +G+ + R+C+DI+EC
Sbjct: 115 DRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQV-VRSRTCQDINECETTNECRE 173
Query: 340 GGQCRNTVGSYTC----TCTDG--LVPSAAGAKPTCQDIDECADLISTII--MMSVDELQ 391
C N G + C C D L P P + C +L +I+ MS+
Sbjct: 174 DEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CRELPQSIVYKYMSI-RSD 230
Query: 392 KSVDPQIPELCGAGSCHNTIGSF 414
+SV I ++ NTI +F
Sbjct: 231 RSVPSDIFQIQATTIYANTINTF 253
Score = 108 bits (259), Expect = 6e-23
Identities = 77/226 (34%), Positives = 96/226 (42%), Gaps = 43/226 (19%)
Query: 328 IDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMS 386
IDEC G C Q C N GS+ C C G G + C DIDEC
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGY--QKRGEQ--CVDIDECT---------- 46
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCH 446
IP C C NT GSF CQC G+ + C D +EC+ C
Sbjct: 47 -----------IPPYCHQ-RCVNTPGSFYCQCSPGFQLAANNY-TCVDINECDASN-QC- 91
Query: 447 PAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCD 504
A C N+ GSF C+C G+ D CED+DEC T++ C + C N G F C+C
Sbjct: 92 -AQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ--CVNEPGKFSCMCP 148
Query: 505 TGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYEC 550
GY+ V +C DI+EC E+ C N GG+ C
Sbjct: 149 QGYQ--------VVRSRTCQDINECETTNECREDEMCWNYHGGFRC 186
Score = 107 bits (257), Expect = 1e-22
Identities = 63/161 (39%), Positives = 82/161 (50%), Gaps = 20/161 (12%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N GSF CQCP GY + EQ C D DEC + CH C+N PGSF C+C G+
Sbjct: 17 CINLRGSFACQCPPGYQKRGEQ---CVDIDECTIPPY-CHQR--CVNTPGSFYCQCSPGF 70
Query: 467 R--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ + TC D++EC +N C + C N GSF C C+ GY+ L +C
Sbjct: 71 QLAANNYTCVDINECDASN-QCAQQ--CYNILGSFICQCNQGYELSSDRL-------NCE 120
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
DIDEC LC+ C N PG + C C G+ + R+C
Sbjct: 121 DIDECRTSSYLCQY-QCVNEPGKFSCMCPQGY-QVVRSRTC 159
Score = 95.1 bits (226), Expect = 6e-19
Identities = 51/130 (39%), Positives = 67/130 (51%), Gaps = 12/130 (9%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANT 495
DEC GT +C CINL GSF C+C G++ G C D+DEC T CH R C NT
Sbjct: 2 DECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDEC-TIPPYCHQR--CVNT 58
Query: 496 DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
GSF C C G+ + Y+CVDI+EC + C C N G + C C+ G
Sbjct: 59 PGSFYCQCSPGF-------QLAANNYTCVDINEC-DASNQCAQ-QCYNILGSFICQCNQG 109
Query: 556 FTRAADGRSC 565
+ ++D +C
Sbjct: 110 YELSSDRLNC 119
Score = 68.1 bits (159), Expect = 8e-11
Identities = 35/91 (38%), Positives = 41/91 (45%), Gaps = 11/91 (12%)
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
+DEC C C N GSF C C GY+ G CVDIDEC P
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRG---------EQCVDIDEC-TIPPY 50
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C C NTPG + C C GF AA+ +C+
Sbjct: 51 CHQ-RCVNTPGSFYCQCSPGFQLAANNYTCV 80
Score = 53.2 bits (122), Expect = 2e-06
Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC LC + +C N G F+C C GY+ ++ TC D+NECE + D C
Sbjct: 121 DIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQV-VRSRTCQDINECETTNECREDEMCW 178
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR 214
N G F C+ R + D + + C ++A+CR
Sbjct: 179 NYHGGFRCYPRNPCQ-DPYILTPENRCVCPVSNAMCR 214
>AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens
cDNA FLJ34743 fis, clone MESAN2009019, moderately
similar to CEGP1 protein. ).
Length = 880
Score = 137 bits (332), Expect = 8e-32
Identities = 118/408 (28%), Positives = 160/408 (39%), Gaps = 38/408 (9%)
Query: 129 CGHGRCRNL-LGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
C H CR GG C+C PG+E C C +G C C +TE C C
Sbjct: 39 CAH-ICRETPKGGIACECRPGFELTKNQRDCKLT--CNYGNGGC-QHTCDDTEQGPRCGC 94
Query: 188 RPGYKADDFSKIC--------------VDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
+ K C V + CA N+ C +C + A C C G
Sbjct: 95 HIKFVLHTDGKTCIGERRLEQHIPTQAVSNETCAVNNGGC-DSKCHDAATGVHCTCPVGF 153
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
L PDR +CKDIDEC + +G C + C N +G+++C C +GY + +
Sbjct: 154 MLQPDRKTCKDIDECRLNNGGCDH-ICRNTVGSFECSCKKGY-KLLINERNCQDIDECSF 211
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C H CVNTPGS+ C C G+ L C D+DEC+ C G C NT GSY CT
Sbjct: 212 DRTCDHICVNTPGSFQCLCHRGYLLYGI-THCGDVDECSINRGGCRFG-CINTPGSYQCT 269
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C G K + + ++ M+S + K + A +
Sbjct: 270 CPAGQGRLHWNGKDCTEPLKCQGSPGASKAMLSCNRSGKKDTCALTCPSRARFLPESENG 329
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD-CINLPGSFQ---CRCRDGWRGD 469
F C + P PA + + CH AA I F+ +CR R
Sbjct: 330 FTVSCG---TPSPRAAPARAGHNGNSTNSNHCHEAAVLSIKQRSPFKIKDAKCRLHLRNK 386
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCL-CDTGYKGDGYGLRT 516
G T E+ +T GG A C+ +F L CD+ KG G RT
Sbjct: 387 GKT-EEAGR-ITGPGG----APCSECQVTFIHLKCDSSRKGKGRRART 428
Score = 124 bits (298), Expect = 1e-27
Identities = 100/310 (32%), Positives = 133/310 (42%), Gaps = 35/310 (11%)
Query: 264 MGTYQCVCDEGYA----QSTVKSHXXXXXXXXXXXXRCQHSCVNTP-GSYHCTCREGWHL 318
MG+Y+C C EG+ Q T C H C TP G C CR G+ L
Sbjct: 2 MGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFEL 61
Query: 319 RADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
+ R C+ C G C C +T C C V G TC I E L
Sbjct: 62 TKNQRDCKLT--CNYGNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGK--TC--IGE-RRL 113
Query: 379 ISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC 438
I +V +V+ C + CH+ C CP G+ ++P++ C D DEC
Sbjct: 114 EQHIPTQAVSNETCAVNNGG---CDS-KCHDAATGVHCTCPVGFMLQPDR-KTCKDIDEC 168
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTD 496
L C C N GSF+C C+ G++ + C+D+DEC + H C NT
Sbjct: 169 RLNNGGCDHI--CRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDH---ICVNTP 223
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
GSF+CLC GY YG+ C D+DEC+ + C G C NTPG Y+C C G
Sbjct: 224 GSFQCLCHRGYLL--YGIT------HCGDVDECSINRGGCRFG-CINTPGSYQCTCPAGQ 274
Query: 557 TRAA-DGRSC 565
R +G+ C
Sbjct: 275 GRLHWNGKDC 284
Score = 99 bits (238), Expect = 2e-20
Identities = 84/320 (26%), Positives = 127/320 (39%), Gaps = 46/320 (14%)
Query: 137 LLGGFTCDCFPGYEKDSKNHTCVDVNE----CEIVDGVCGDGDCHNTEGSFTCHCRPGYK 192
++G + C C G+ HTC+ E C + C +G C CRPG++
Sbjct: 1 MMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFE 60
Query: 193 ADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSC-------KDI 245
+ C C + C+ C +T RC C L D +C + I
Sbjct: 61 LTKNQRDCK--LTCNYGNGGCQ-HTCDDTEQGPRCGCHIKFVLHTDGKTCIGERRLEQHI 117
Query: 246 DECSITSGIC--SNGACENQMGT----YQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
++++ C +NG C+++ C C G+ + C H
Sbjct: 118 PTQAVSNETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH 177
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C NT GS+ C+C++G+ L + R+C+DIDEC+ R C C NT GS+ C C G +
Sbjct: 178 ICRNTVGSFECSCKKGYKLLINERNCQDIDECSFD-RTC-DHICVNTPGSFQCLCHRGYL 235
Query: 360 PSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCP 419
C D+DEC S++ C G C NT GS+ C CP
Sbjct: 236 LYGI---THCGDVDEC----------SINR----------GGCRFG-CINTPGSYQCTCP 271
Query: 420 DGYSVKPEQGPACTDDDECE 439
G G CT+ +C+
Sbjct: 272 AGQGRLHWNGKDCTEPLKCQ 291
Score = 38.3 bits (85), Expect = 0.072
Identities = 42/175 (24%), Positives = 67/175 (38%), Gaps = 23/175 (13%)
Query: 401 LCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDD--------ECELG--TCDCHPAAD 450
+ G+ CH G F+ +PE+G C + + E G C+C P +
Sbjct: 1 MMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFE 60
Query: 451 CINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
+ C G G TC+D ++ GCH + +TDG C+ G +
Sbjct: 61 LTKNQRDCKLTCNYGNGGCQHTCDDTEQ--GPRCGCHIKFV-LHTDGK-TCI---GERRL 113
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+ T V + CA + C++ C + G C C VGF D ++C
Sbjct: 114 EQHIPT-----QAVSNETCAVNNGGCDS-KCHDAATGVHCTCPVGFMLQPDRKTC 162
>AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.
Length = 1200
Score = 134 bits (324), Expect = 8e-31
Identities = 127/461 (27%), Positives = 180/461 (39%), Gaps = 84/461 (18%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
Q++VN+C G C HG C++L+ G+ C C G+ H ++ ++C C G
Sbjct: 421 QLDVNDCR---GQCQHGGTCKDLVNGYQCVCPRGF---GGRHCELERDKC--ASSPCHSG 472
Query: 175 D-CHNTEGSFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGG-RCVNTAGSFRCECGH 231
C + F CHC G+ +C VD+D C + CR G RC N G + C C
Sbjct: 473 GLCEDLADGFHCHCPQGFSGP----LCEVDVDLCEPSP--CRNGARCYNLEGDYYCAC-- 524
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
PD K+ CS+ C GAC G C D G +
Sbjct: 525 -----PDDFGGKN---CSVPREPCPGGACRVIDG---CGSDAGPGMPGTAASGVCGPHGR 573
Query: 292 XXXXRCQHSCVNTPG-SYHCTCREGWHLRADGRSCRD-IDECAGGARPC-GGGQCRNTVG 348
CV+ PG ++ C C G+ G C + ID+C G +PC GG C + V
Sbjct: 574 ---------CVSQPGGNFSCICDSGF----TGTYCHENIDDCLG--QPCRNGGTCIDEVD 618
Query: 349 SYTCTCTDGLVPSAAGAKPT------CQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
++ C C G P C C DL++ D + C
Sbjct: 619 AFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQC 678
Query: 403 GA------GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPG 456
A G+C+++ +F C CP G+ +G C C C+
Sbjct: 679 DAYTCSNGGTCYDSGDTFRCACPPGW-----KGSTCAVAKNSSCLPNPCVNGGTCVGSGA 733
Query: 457 SFQCRCRDGWRGDGATC-EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
SF C CRDGW +G TC + ++C N C+ C + FRC C G+ G
Sbjct: 734 SFSCICRDGW--EGRTCTHNTNDC--NPLPCYNGGICVDGVNWFRCECAPGFAGPD---- 785
Query: 516 TVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVG 555
C ++IDEC + P C G C + GY C C G
Sbjct: 786 --C----RINIDECQSSP--CAYGATCVDEINGYRCSCPPG 818
Score = 113 bits (271), Expect = 2e-24
Identities = 113/454 (24%), Positives = 174/454 (38%), Gaps = 66/454 (14%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDCHNTE 180
C + P G G C + GF C C G+ TC +D++EC G G C +
Sbjct: 351 CTSNPCANG-GSCHEVPSGFECHCPSGWS----GPTCALDIDECASNPCAAG-GTCVDQV 404
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDR 239
F C C + + +D+++C C+ GG C + ++C C G
Sbjct: 405 DGFECICPEQWVG---ATCQLDVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGFGGRHCE 458
Query: 240 LSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
L + D+C+ +S S G CE+ + C C +G++ + R
Sbjct: 459 L---ERDKCA-SSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---VDVDLCEPSPCRNGA 511
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C N G Y+C C + + G++C E PC GG CR G C G
Sbjct: 512 RCYNLEGDYYCACPDDF----GGKNCSVPRE------PCPGGACRVIDG---CGSDAGPG 558
Query: 360 PSAAGAKPTCQDIDECADLISTIIMMSVDE------LQKSVDPQIPELC-GAGSCHNTIG 412
A C C D +++D + + C G+C + +
Sbjct: 559 MPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVD 618
Query: 413 SFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
+F C CP G+ +G C T+ ++C C H C +L F C C DGW+ G
Sbjct: 619 AFRCFCPSGW-----EGELCDTNPNDCLPDPC--HSRGRCYDLVNDFYCACDDGWK--GK 669
Query: 472 TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAN 531
TC E + C TC ++ +FRC C G+KG + C V C
Sbjct: 670 TCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKG------STCAV---AKNSSCLP 719
Query: 532 DPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+P + G C + + C C G+ +GR+C
Sbjct: 720 NPCV-NGGTCVGSGASFSCICRDGW----EGRTC 748
Score = 111 bits (267), Expect = 6e-24
Identities = 120/463 (25%), Positives = 179/463 (38%), Gaps = 74/463 (15%)
Query: 128 LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
+C G C L GG T PG + S +EC G C G C + C+C
Sbjct: 244 VCKQG-CNLLHGGCTV---PGECRCSYGWQGRFCDECVPYPG-CVHGSCVEP---WQCNC 295
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGGRCVNTA-GSFRCECGHGMELAPDRLSCKDID 246
+ K D++ C + GG C+N +RC C G +C+ +
Sbjct: 296 ETNWGGLLCDK---DLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYS----GRNCEKAE 348
Query: 247 ECSITSGICSNG-ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTP 305
+ TS C+NG +C ++C C G++ T +CV+
Sbjct: 349 H-ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC---ALDIDECASNPCAAGGTCVDQV 404
Query: 306 GSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCTCTDGL------ 358
+ C C E W G +C+ D+++C G + GG C++ V Y C C G
Sbjct: 405 DGFECICPEQW----VGATCQLDVNDCRGQCQ--HGGTCKDLVNGYQCVCPRGFGGRHCE 458
Query: 359 VPSAAGAKPTCQDIDECADLISTIIM-----MSVDELQKSVDPQIPELCGAGS-CHNTIG 412
+ A C C DL S + VD P C G+ C+N G
Sbjct: 459 LERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEG 518
Query: 413 SFVCQCPDGYSVK-------PEQGPACTDDDECEL-------GTCD---CHPAADCINLP 455
+ C CPD + K P G AC D C GT C P C++ P
Sbjct: 519 DYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQP 578
Query: 456 -GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGL 514
G+F C C G+ G E++D+CL C TC + +FRC C +G++G+
Sbjct: 579 GGNFSCICDSGFTGTYCH-ENIDDCL--GQPCRNGGTCIDEVDAFRCFCPSGWEGE---- 631
Query: 515 RTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
+C + ++C DP C + G C + + C CD G+
Sbjct: 632 --LC----DTNPNDCLPDP--CHSRGRCYDLVNDFYCACDDGW 666
Score = 103 bits (248), Expect = 1e-21
Identities = 116/431 (26%), Positives = 168/431 (38%), Gaps = 86/431 (19%)
Query: 176 CHNTEGSFTCH--CRPG------YKADDF-SKICVDI---DECADNDALCRGGRCVNTAG 223
C S TC+ CRP Y D + +K C+D EC +A+C+ G + G
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKEC--KEAVCKQGCNLLHGG 255
Query: 224 SF---RCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTV 280
C C +G + + DEC G C +G+C + +QC C+ +
Sbjct: 256 CTVPGECRCSYGWQ-------GRFCDECVPYPG-CVHGSC---VEPWQCNCETNWGGLLC 304
Query: 281 KSHXXXXXXXXXXXXRCQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
+C+N P Y CTC +G+ GR+C + A + PC
Sbjct: 305 DKDLNYCGSHHPCTNG--GTCINAEPDQYRCTCPDGY----SGRNCEKAEH-ACTSNPCA 357
Query: 340 -GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQ--KSVD 395
GG C + C C G + PTC DIDECA VD++ + +
Sbjct: 358 NGGSCHEVPSGFECHCPSG------WSGPTCALDIDECASNPCAAGGTCVDQVDGFECIC 411
Query: 396 PQ--IPELC------------GAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECEL 440
P+ + C G+C + + + C CP G+ G C + D+C
Sbjct: 412 PEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFG-----GRHCELERDKC-- 464
Query: 441 GTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSF 499
+ CH C +L F C C G+ G CE DVD C C A C N +G +
Sbjct: 465 ASSPCHSGGLCEDLADGFHCHCPQGF--SGPLCEVDVDLC--EPSPCRNGARCYNLEGDY 520
Query: 500 RCLCDTGYKGDGYGL-RTVCCVYSCVDIDECAND----------PTLC-ENGHCSNTPGG 547
C C + G + R C +C ID C +D +C +G C + PGG
Sbjct: 521 YCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGG 580
Query: 548 -YECDCDVGFT 557
+ C CD GFT
Sbjct: 581 NFSCICDSGFT 591
>AK027775-1|BAB55358.1| 537|Homo sapiens protein ( Homo sapiens
cDNA FLJ14869 fis, clone PLACE1002474, moderately
similar to Mus musculus matrilin-2 precursor mRNA. ).
Length = 537
Score = 134 bits (323), Expect = 1e-30
Identities = 73/226 (32%), Positives = 99/226 (43%), Gaps = 4/226 (1%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKIC 200
+ C C GY D TC V+ C D C + C NTE SF C C G+ ++ C
Sbjct: 5 YYCRCHRGYTLDPNGKTCSRVDHCAQQDHGC-EQLCLNTEDSFVCQCSEGFLINEDLMTC 63
Query: 201 VDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGAC 260
+D C +D C CVN SF C+C G L D +C +D C++ C + +C
Sbjct: 64 SRVDYCLLSDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-SC 121
Query: 261 ENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRA 320
+ ++ C C EGY C+H CVN+ SY C C EG+ L
Sbjct: 122 VSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAE 181
Query: 321 DGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAK 366
DG+ CR D C C C N SY C C++G V + G +
Sbjct: 182 DGKRCRRKDVCKSTHHGC-EHICVNNGNSYICKCSEGFVLAEDGRR 226
Score = 122 bits (293), Expect = 5e-27
Identities = 64/196 (32%), Positives = 91/196 (46%), Gaps = 5/196 (2%)
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDR 239
E S+ C C GY D K C +D CA D C C+NT SF C+C G + D
Sbjct: 2 EESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCE-QLCLNTEDSFVCQCSEGFLINEDL 60
Query: 240 LSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
++C +D C ++ C +C N ++ C C EG+ + C+H
Sbjct: 61 MTCSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH 119
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
SCV++ S+ C C EG+ LR DG++CR D C C C N+ SYTC C +G
Sbjct: 120 SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGC-EHICVNSDDSYTCECLEGFR 178
Query: 360 PSAAGAKPTCQDIDEC 375
+ G + C+ D C
Sbjct: 179 LAEDGKR--CRRKDVC 192
Score = 119 bits (286), Expect = 3e-26
Identities = 82/261 (31%), Positives = 115/261 (44%), Gaps = 39/261 (14%)
Query: 307 SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAK 366
SY+C C G+ L +G++C +D CA C C NT S+ C C++G + +
Sbjct: 4 SYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINED--L 60
Query: 367 PTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKP 426
TC +D C ++S + S C N SF CQCP+G+ ++
Sbjct: 61 MTCSRVDYC--------LLSDHGCEYS-------------CVNMDRSFACQCPEGHVLRS 99
Query: 427 EQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATCEDVDECLTNNG 484
+ G C D C LG C + C++ SF C+C +G+ R DG TC D C +
Sbjct: 100 D-GKTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDH 156
Query: 485 GCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNT 544
GC C N+D S+ C C G++ G R C D C + CE+ C N
Sbjct: 157 GCEH--ICVNSDDSYTCECLEGFRLAEDGKR-------CRRKDVCKSTHHGCEH-ICVNN 206
Query: 545 PGGYECDCDVGFTRAADGRSC 565
Y C C GF A DGR C
Sbjct: 207 GNSYICKCSEGFVLAEDGRRC 227
Score = 115 bits (277), Expect = 4e-25
Identities = 67/212 (31%), Positives = 88/212 (41%), Gaps = 4/212 (1%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
V+ CA C C N F C C G+ + TC V+ C + D C + C N
Sbjct: 25 VDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLMTCSRVDYCLLSDHGC-EYSCVN 82
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
+ SF C C G+ K C +D CA D C CV++ SF C+C G L D
Sbjct: 83 MDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS-CVSSEDSFVCQCFEGYILRED 141
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
+C+ D C C + C N +Y C C EG+ + C+
Sbjct: 142 GKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCE 200
Query: 299 HSCVNTPGSYHCTCREGWHLRADGRSCRDIDE 330
H CVN SY C C EG+ L DGR C+ E
Sbjct: 201 HICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 232
Score = 100 bits (239), Expect = 2e-20
Identities = 72/263 (27%), Positives = 102/263 (38%), Gaps = 31/263 (11%)
Query: 266 TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
+Y C C GY C+ C+NT S+ C C EG+ + D +C
Sbjct: 4 SYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLMTC 63
Query: 326 RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
+D C C C N S+ C C +G V + G TC +D CA
Sbjct: 64 SRVDYCLLSDHGCEYS-CVNMDRSFACQCPEGHVLRSDGK--TCAKLDSCA--------- 111
Query: 386 SVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDC 445
+ + SC ++ SFVCQC +GY ++ E G C D C+ C
Sbjct: 112 ------------LGDHGCEHSCVSSEDSFVCQCFEGYILR-EDGKTCRRKDVCQAIDHGC 158
Query: 446 HPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C+N S+ C C +G+R DG C D C + + GC C N S+ C C
Sbjct: 159 EHI--CVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH--ICVNNGNSYICKC 214
Query: 504 DTGYKGDGYGLRTVCCVYSCVDI 526
G+ G R C +D+
Sbjct: 215 SEGFVLAEDGRRCKKCTEGPIDL 237
Score = 92.3 bits (219), Expect = 4e-18
Identities = 58/166 (34%), Positives = 79/166 (47%), Gaps = 19/166 (11%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C NT SFVCQC +G+ + E C+ D C L C + C+N+ SF C+C +G
Sbjct: 39 CLNTEDSFVCQCSEGFLIN-EDLMTCSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGH 95
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY--KGDGYGLRTVCCVYS 522
R DG TC +D C + GC +C +++ SF C C GY + DG +
Sbjct: 96 VLRSDGKTCAKLDSCALGDHGCEH--SCVSSEDSFVCQCFEGYILREDGK---------T 144
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
C D C CE+ C N+ Y C+C GF A DG+ C K
Sbjct: 145 CRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRK 189
Score = 85.4 bits (202), Expect = 5e-16
Identities = 51/160 (31%), Positives = 74/160 (46%), Gaps = 19/160 (11%)
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDG 470
S+ C+C GY++ P G C+ D C C C+N SF C+C +G+ D
Sbjct: 4 SYYCRCHRGYTLDP-NGKTCSRVDHCAQQDHGCEQL--CLNTEDSFVCQCSEGFLINEDL 60
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY--KGDGYGLRTVCCVYSCVDIDE 528
TC VD CL ++ GC +C N D SF C C G+ + DG +C +D
Sbjct: 61 MTCSRVDYCLLSDHGC--EYSCVNMDRSFACQCPEGHVLRSDG---------KTCAKLDS 109
Query: 529 CANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCLGK 568
CA CE+ C ++ + C C G+ DG++C K
Sbjct: 110 CALGDHGCEHS-CVSSEDSFVCQCFEGYILREDGKTCRRK 148
>AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein.
Length = 451
Score = 133 bits (322), Expect = 1e-30
Identities = 68/204 (33%), Positives = 96/204 (47%), Gaps = 4/204 (1%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C+ C H C N+ G + C C GY +S TC + C + D C + C N G
Sbjct: 242 CSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC-EQLCVNVPG 299
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
SF C C GY + K CV +D CA + C CVN GS+ C+C G L PD+ +
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKT 358
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSC 301
C ID C+ ++ C + C N +Y C C +G+ + K C+H C
Sbjct: 359 CTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHEC 417
Query: 302 VNTPGSYHCTCREGWHLRADGRSC 325
VN SY+C C G+ L +G++C
Sbjct: 418 VNMEESYYCRCHRGYTLDPNGKTC 441
Score = 124 bits (300), Expect = 6e-28
Identities = 67/182 (36%), Positives = 84/182 (46%), Gaps = 3/182 (1%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N GS+ C C+ GY + C D CA D C CVN GSF C+C G L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
A D C +D C+ + C + C N G+Y C C EG+A + K
Sbjct: 312 AEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNH 370
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCT 355
CQH CVNT SY C C +G+ L D ++CR I+ CA C +C N SY C C
Sbjct: 371 GCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC-EHECVNMEESYYCRCH 429
Query: 356 DG 357
G
Sbjct: 430 RG 431
Score = 109 bits (263), Expect = 2e-23
Identities = 69/220 (31%), Positives = 95/220 (43%), Gaps = 33/220 (15%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C H C+N PGSY C C++G+ L +D +CR D CA C C N GS+ C C
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC-EQLCVNVPGSFVCQCYS 307
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGSFV 415
G + G + C +D CA E G C N GS++
Sbjct: 308 GYALAEDGKR--CVAVDYCAS----------------------ENHGCEHECVNADGSYL 343
Query: 416 CQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATC 473
CQC +G+++ P++ CT D C C +C+N S+ C C G+ D TC
Sbjct: 344 CQCHEGFALNPDK-KTCTKIDYCASSNHGCQ--HECVNTDDSYSCHCLKGFTLNPDKKTC 400
Query: 474 EDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
++ C N GC C N + S+ C C GY D G
Sbjct: 401 RRINYCALNKPGCEHE--CVNMEESYYCRCHRGYTLDPNG 438
Score = 104 bits (249), Expect = 1e-21
Identities = 58/161 (36%), Positives = 78/161 (48%), Gaps = 15/161 (9%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N GS+VC+C GY + +Q C D C + +C C+N+PGSF C+C G+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQ-TTCRIQDLCAMEDHNCEQL--CVNVPGSFVCQCYSGY 309
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
DG C VD C + N GC C N DGS+ C C +G+ L +C
Sbjct: 310 ALAEDGKRCVAVDYCASENHGCEHE--CVNADGSYLCQCH-----EGFALNP--DKKTCT 360
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
ID CA+ C++ C NT Y C C GFT D ++C
Sbjct: 361 KIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTC 400
Score = 97.1 bits (231), Expect = 1e-19
Identities = 71/225 (31%), Positives = 100/225 (44%), Gaps = 38/225 (16%)
Query: 343 CRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
C N GSY C C G + ++ + TC+ D CA D +LC
Sbjct: 253 CINIPGSYVCRCKQGYILNSD--QTTCRIQDLCA----------------MEDHNCEQLC 294
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC 462
N GSFVCQC GY++ E G C D C C +C+N GS+ C+C
Sbjct: 295 V-----NVPGSFVCQCYSGYAL-AEDGKRCVAVDYCASENHGCE--HECVNADGSYLCQC 346
Query: 463 RDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
+G+ D TC +D C ++N GC + C NTD S+ C C G+ + +T
Sbjct: 347 HEGFALNPDKKTCTKIDYCASSNHGC--QHECVNTDDSYSCHCLKGFTLNP-DKKT---- 399
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C I+ CA + CE+ C N Y C C G+T +G++C
Sbjct: 400 --CRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTC 441
Score = 46.4 bits (105), Expect = 3e-04
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 8/75 (10%)
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
C N GS+ C C GY + +T C + D CA + CE C N PG + C
Sbjct: 253 CINIPGSYVCRCKQGYILNSD--QTTCRIQ-----DLCAMEDHNCEQ-LCVNVPGSFVCQ 304
Query: 552 CDVGFTRAADGRSCL 566
C G+ A DG+ C+
Sbjct: 305 CYSGYALAEDGKRCV 319
>AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA
sequence from clone GS1-174L6 on chromosome 1. ).
Length = 240
Score = 129 bits (312), Expect = 2e-29
Identities = 72/180 (40%), Positives = 93/180 (51%), Gaps = 11/180 (6%)
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCE--CGHGMELAP 237
GSF C C PGY+ + C+D++EC N +CR + C NT G ++C C +GM A
Sbjct: 3 GSFHCGCEPGYQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMTKAE 58
Query: 238 DRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
+ +C DIDEC + C N CEN G+Y+CVC GY V
Sbjct: 59 NG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGV-GRPCMDIDECENTDA 116
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCT 355
CQH C NT GSY C C G+ L +G++C+DIDEC CG + C N GSY C T
Sbjct: 117 CQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDT 176
Score = 123 bits (296), Expect = 2e-27
Identities = 88/241 (36%), Positives = 116/241 (48%), Gaps = 42/241 (17%)
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCT--CTDGLVPSA 362
GS+HC C G+ L+ GR C D++EC C Q C+NT G Y C C +G+ +
Sbjct: 3 GSFHCGCEPGYQLK--GRKCMDVNECRQNV--CRPDQHCKNTRGGYKCIDLCPNGMTKAE 58
Query: 363 AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGY 422
G TC DIDEC D + + + QI C NT GS+ C CP GY
Sbjct: 59 NG---TCIDIDECKD--------GTHQCRYN---QI--------CENTRGSYRCVCPRGY 96
Query: 423 SVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECL 480
+ P C D DECE T C +C N GS+QC C G++ +G TC+D+DECL
Sbjct: 97 RSQGVGRP-CMDIDECE-NTDACQH--ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECL 152
Query: 481 TNNGGCHPRATCANTDGSFRCL---CDTGYKGDGYGLRTVCCVYSCVDID-ECANDPTLC 536
N C P C N GS++C+ C Y+ D + C+ +C D ECA P
Sbjct: 153 EQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPV---SGFCLKNCPPNDLECALSPYAL 209
Query: 537 E 537
E
Sbjct: 210 E 210
Score = 118 bits (284), Expect = 6e-26
Identities = 64/171 (37%), Positives = 92/171 (53%), Gaps = 11/171 (6%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTC-DCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
M+VNEC +C + C+N GG+ C D P ++N TC+D++EC+ C
Sbjct: 21 MDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYN 78
Query: 175 D-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C NT GS+ C C GY++ + C+DIDEC + DA C+ C NT GS++C C G
Sbjct: 79 QICENTRGSYRCVCPRGYRSQGVGRPCMDIDECENTDA-CQ-HECKNTFGSYQCICPPGY 136
Query: 234 ELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCV---CDEGYAQSTV 280
+L + +C+DIDEC + C N C N G+YQC+ C Y + V
Sbjct: 137 QLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPV 187
Score = 111 bits (268), Expect = 5e-24
Identities = 59/158 (37%), Positives = 78/158 (49%), Gaps = 17/158 (10%)
Query: 411 IGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC--RCRDGW-R 467
IGSF C C GY +K G C D +EC C P C N G ++C C +G +
Sbjct: 2 IGSFHCGCEPGYQLK---GRKCMDVNECRQNVC--RPDQHCKNTRGGYKCIDLCPNGMTK 56
Query: 468 GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
+ TC D+DEC C C NT GS+RC+C GY+ G G C+DID
Sbjct: 57 AENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG-------RPCMDID 109
Query: 528 ECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
EC N C++ C NT G Y+C C G+ +G++C
Sbjct: 110 ECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTC 145
Score = 111 bits (267), Expect = 6e-24
Identities = 68/180 (37%), Positives = 83/180 (46%), Gaps = 15/180 (8%)
Query: 138 LGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSFTC--HCRPGY-KA 193
+G F C C PGY+ K C+DVNEC VC D C NT G + C C G KA
Sbjct: 2 IGSFHCGCEPGYQ--LKGRKCMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 57
Query: 194 DDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGMELAPDRLSCKDIDECSITS 252
++ + C+DIDEC D CR + C NT GS+RC C G C DIDEC T
Sbjct: 58 ENGT--CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECENTD 115
Query: 253 GICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC--QHSCVNTPGSYHC 310
C + C+N G+YQC+C GY + C C N GSY C
Sbjct: 116 A-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 173
Score = 94.7 bits (225), Expect = 8e-19
Identities = 56/160 (35%), Positives = 77/160 (48%), Gaps = 14/160 (8%)
Query: 223 GSFRCECGHGMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCV--CDEGYAQST 279
GSF C C G +L + C D++EC +C + C+N G Y+C+ C G ++
Sbjct: 3 GSFHCGCEPGYQLKGRK--CMDVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE 58
Query: 280 VKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARP 337
+C+++ C NT GSY C C G+ + GR C DIDEC
Sbjct: 59 -NGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECEN-TDA 116
Query: 338 CGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECAD 377
C +C+NT GSY C C G + G TCQDIDEC +
Sbjct: 117 CQH-ECKNTFGSYQCICPPGYQLTHNG--KTCQDIDECLE 153
Score = 78.2 bits (184), Expect = 7e-14
Identities = 43/114 (37%), Positives = 53/114 (46%), Gaps = 13/114 (11%)
Query: 456 GSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRC--LCDTGYKGDGYG 513
GSF C C G++ G C DV+EC N C P C NT G ++C LC G G
Sbjct: 3 GSFHCGCEPGYQLKGRKCMDVNECRQNV--CRPDQHCKNTRGGYKCIDLCPNGMTKAENG 60
Query: 514 LRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C+DIDEC + C N C NT G Y C C G+ GR C+
Sbjct: 61 --------TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCM 106
>AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein
protein.
Length = 652
Score = 126 bits (305), Expect = 2e-28
Identities = 71/193 (36%), Positives = 88/193 (45%), Gaps = 12/193 (6%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCH-NTEG-SFTCHCRPGYKADD 195
G F C C PG+ TC N C C G C G ++TC C GY+ D
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCALGPHGKNYTCRCPQGYQLDS 338
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL-APDRLSCKDIDECSITSGI 254
CVD+DEC D+ CVNT G FRCEC G E P +C+D+DEC++
Sbjct: 339 SQLDCVDVDECQDSPC---AQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 255 CSNGACENQMGTYQCVCDEGY--AQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTC 312
C+ G C N G++ C C+EGY A C C NT GS+HC C
Sbjct: 396 CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGC 454
Query: 313 REGWHLRADGRSC 325
GW L +G SC
Sbjct: 455 LPGWVLAPNGVSC 467
Score = 123 bits (297), Expect = 1e-27
Identities = 69/210 (32%), Positives = 94/210 (44%), Gaps = 10/210 (4%)
Query: 164 CEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR--CVNT 221
C +G C +GSF C CRPG++ D C + C+ + CRGG +
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCALGP 321
Query: 222 AG-SFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTV 280
G ++ C C G +L +L C D+DEC + C+ C N G ++C C GY
Sbjct: 322 HGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGP 378
Query: 281 -KSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRA-DGRSCRDIDECAGGARPC 338
+ C C NT GS+HC+C EG+ L DG C+D+DEC G P
Sbjct: 379 GEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPL 438
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAAGAKPT 368
C NT GS+ C C G V + G T
Sbjct: 439 CDSLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
Score = 108 bits (259), Expect = 6e-23
Identities = 61/158 (38%), Positives = 79/158 (50%), Gaps = 20/158 (12%)
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR----G 468
++ C+CP GY + Q C D DEC+ C A +C+N PG F+C C G+ G
Sbjct: 325 NYTCRCPQGYQLDSSQLD-CVDVDECQDSPC----AQECVNTPGGFRCECWVGYEPGGPG 379
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
+GA C+DVDEC C C NTDGSF C C+ GY G C D+DE
Sbjct: 380 EGA-CQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYVLAGEDGT------QCQDVDE 430
Query: 529 CANDP-TLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C LC++ C NT G + C C G+ A +G SC
Sbjct: 431 CVGPGGPLCDS-LCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 105 bits (251), Expect = 6e-22
Identities = 78/218 (35%), Positives = 94/218 (43%), Gaps = 37/218 (16%)
Query: 297 CQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQCR-NTVG-SYTC 352
C C GS+ C CR G+ L D +C + C+ PC GG C G +YTC
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSS--PCRGGATCALGPHGKNYTC 328
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C G ++ C D+DEC D P C A C NT G
Sbjct: 329 RCPQGY--QLDSSQLDCVDVDECQD-----------------SP-----C-AQECVNTPG 363
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW---RGD 469
F C+C GY AC D DEC LG C A C N GSF C C +G+ D
Sbjct: 364 GFRCECWVGYEPGGPGEGACQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYVLAGED 421
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
G C+DVDEC+ GG + C NT GSF C C G+
Sbjct: 422 GTQCQDVDECV-GPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 100 bits (239), Expect = 2e-20
Identities = 72/230 (31%), Positives = 94/230 (40%), Gaps = 30/230 (13%)
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPG- 306
C+ +G C E G++ C C G+ R +C P
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHG 323
Query: 307 -SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGA 365
+Y C C +G+ L + C D+DEC PC +C NT G + C C G P G
Sbjct: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQDS--PCAQ-ECVNTPGGFRCECWVGYEPGGPG- 379
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVK 425
+ CQD+DECA L +S C G C NT GSF C C +GY +
Sbjct: 380 EGACQDVDECA-------------LGRSP-------CAQG-CTNTDGSFHCSCEEGYVLA 418
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATC 473
E G C D DEC +G + C N GSF C C GW +G +C
Sbjct: 419 GEDGTQCQDVDEC-VGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 97.5 bits (232), Expect = 1e-19
Identities = 52/128 (40%), Positives = 64/128 (50%), Gaps = 6/128 (4%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNH-TCVDVNECEIVDGVCGDGD 175
++V+EC P C C N GGF C+C+ GYE C DV+EC + C G
Sbjct: 344 VDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG- 399
Query: 176 CHNTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C NT+GSF C C GY A + C D+DEC C NT GSF C C G
Sbjct: 400 CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWV 459
Query: 235 LAPDRLSC 242
LAP+ +SC
Sbjct: 460 LAPNGVSC 467
Score = 41.9 bits (94), Expect = 0.006
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 14/105 (13%)
Query: 466 WRGDGATCEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
W G C C NNGGCH + DGSF C C G+ R + + +C
Sbjct: 250 WGSSGPLCVSPKYGCNFNNGGCH-QDCFEGGDGSFLCGCRPGF-------RLLDDLVTCA 301
Query: 525 DIDECANDPTLCENG-HCSNTPGG--YECDCDVGFTRAADGRSCL 566
+ C++ P C G C+ P G Y C C G+ + C+
Sbjct: 302 SRNPCSSSP--CRGGATCALGPHGKNYTCRCPQGYQLDSSQLDCV 344
>U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein.
Length = 652
Score = 126 bits (304), Expect = 2e-28
Identities = 71/193 (36%), Positives = 88/193 (45%), Gaps = 12/193 (6%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDC-HNTEG-SFTCHCRPGYKADD 195
G F C C PG+ TC N C C G C G ++TC C GY+ D
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL-APDRLSCKDIDECSITSGI 254
CVD+DEC D+ CVNT G FRCEC G E P +C+D+DEC++
Sbjct: 339 SQLDCVDVDECQDSPC---AQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 255 CSNGACENQMGTYQCVCDEGY--AQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTC 312
C+ G C N G++ C C+EGY A C C NT GS+HC C
Sbjct: 396 CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGC 454
Query: 313 REGWHLRADGRSC 325
GW L +G SC
Sbjct: 455 LPGWVLAPNGVSC 467
Score = 124 bits (300), Expect = 6e-28
Identities = 70/210 (33%), Positives = 94/210 (44%), Gaps = 10/210 (4%)
Query: 164 CEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CV--N 220
C +G C +GSF C CRPG++ D C + C+ + CRGG CV
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGP 321
Query: 221 TAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTV 280
++ C C G +L +L C D+DEC + C+ C N G ++C C GY
Sbjct: 322 HGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGP 378
Query: 281 -KSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRA-DGRSCRDIDECAGGARPC 338
+ C C NT GS+HC+C EG+ L DG C+D+DEC G P
Sbjct: 379 GEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPL 438
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAAGAKPT 368
C NT GS+ C C G V + G T
Sbjct: 439 CDSLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
Score = 108 bits (259), Expect = 6e-23
Identities = 61/158 (38%), Positives = 79/158 (50%), Gaps = 20/158 (12%)
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR----G 468
++ C+CP GY + Q C D DEC+ C A +C+N PG F+C C G+ G
Sbjct: 325 NYTCRCPQGYQLDSSQLD-CVDVDECQDSPC----AQECVNTPGGFRCECWVGYEPGGPG 379
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
+GA C+DVDEC C C NTDGSF C C+ GY G C D+DE
Sbjct: 380 EGA-CQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYVLAGEDGT------QCQDVDE 430
Query: 529 CANDP-TLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C LC++ C NT G + C C G+ A +G SC
Sbjct: 431 CVGPGGPLCDS-LCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 104 bits (250), Expect = 7e-22
Identities = 78/218 (35%), Positives = 94/218 (43%), Gaps = 37/218 (16%)
Query: 297 CQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQC-RNTVG-SYTC 352
C C GS+ C CR G+ L D +C + C+ PC GG C G +YTC
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSS--PCRGGATCVLGPHGKNYTC 328
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C G ++ C D+DEC D P C A C NT G
Sbjct: 329 RCPQGY--QLDSSQLDCVDVDECQD-----------------SP-----C-AQECVNTPG 363
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW---RGD 469
F C+C GY AC D DEC LG C A C N GSF C C +G+ D
Sbjct: 364 GFRCECWVGYEPGGPGEGACQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYVLAGED 421
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
G C+DVDEC+ GG + C NT GSF C C G+
Sbjct: 422 GTQCQDVDECV-GPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 101 bits (243), Expect = 5e-21
Identities = 73/230 (31%), Positives = 95/230 (41%), Gaps = 30/230 (13%)
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPG- 306
C+ +G C E G++ C C G+ R +CV P
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
Query: 307 -SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGA 365
+Y C C +G+ L + C D+DEC PC +C NT G + C C G P G
Sbjct: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQDS--PCAQ-ECVNTPGGFRCECWVGYEPGGPG- 379
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVK 425
+ CQD+DECA L +S C G C NT GSF C C +GY +
Sbjct: 380 EGACQDVDECA-------------LGRSP-------CAQG-CTNTDGSFHCSCEEGYVLA 418
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATC 473
E G C D DEC +G + C N GSF C C GW +G +C
Sbjct: 419 GEDGTQCQDVDEC-VGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 97.5 bits (232), Expect = 1e-19
Identities = 52/128 (40%), Positives = 64/128 (50%), Gaps = 6/128 (4%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNH-TCVDVNECEIVDGVCGDGD 175
++V+EC P C C N GGF C+C+ GYE C DV+EC + C G
Sbjct: 344 VDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG- 399
Query: 176 CHNTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C NT+GSF C C GY A + C D+DEC C NT GSF C C G
Sbjct: 400 CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWV 459
Query: 235 LAPDRLSC 242
LAP+ +SC
Sbjct: 460 LAPNGVSC 467
Score = 40.7 bits (91), Expect = 0.013
Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 14/105 (13%)
Query: 466 WRGDGATCEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
W G C C NNGGCH + DGSF C C G+ R + + +C
Sbjct: 250 WGSSGPLCVSPKYGCNFNNGGCH-QDCFEGGDGSFLCGCRPGF-------RLLDDLVTCA 301
Query: 525 DIDECANDPTLCENG-HCSNTPGG--YECDCDVGFTRAADGRSCL 566
+ C++ P C G C P G Y C C G+ + C+
Sbjct: 302 SRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCV 344
>BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein.
Length = 652
Score = 126 bits (304), Expect = 2e-28
Identities = 71/193 (36%), Positives = 88/193 (45%), Gaps = 12/193 (6%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDC-HNTEG-SFTCHCRPGYKADD 195
G F C C PG+ TC N C C G C G ++TC C GY+ D
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL-APDRLSCKDIDECSITSGI 254
CVD+DEC D+ CVNT G FRCEC G E P +C+D+DEC++
Sbjct: 339 SQLDCVDVDECQDSPC---AQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 255 CSNGACENQMGTYQCVCDEGY--AQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTC 312
C+ G C N G++ C C+EGY A C C NT GS+HC C
Sbjct: 396 CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGC 454
Query: 313 REGWHLRADGRSC 325
GW L +G SC
Sbjct: 455 LPGWVLAPNGVSC 467
Score = 124 bits (300), Expect = 6e-28
Identities = 70/210 (33%), Positives = 94/210 (44%), Gaps = 10/210 (4%)
Query: 164 CEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CV--N 220
C +G C +GSF C CRPG++ D C + C+ + CRGG CV
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGP 321
Query: 221 TAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTV 280
++ C C G +L +L C D+DEC + C+ C N G ++C C GY
Sbjct: 322 HGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGP 378
Query: 281 -KSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRA-DGRSCRDIDECAGGARPC 338
+ C C NT GS+HC+C EG+ L DG C+D+DEC G P
Sbjct: 379 GEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPL 438
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAAGAKPT 368
C NT GS+ C C G V + G T
Sbjct: 439 CDSLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
Score = 108 bits (259), Expect = 6e-23
Identities = 61/158 (38%), Positives = 79/158 (50%), Gaps = 20/158 (12%)
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR----G 468
++ C+CP GY + Q C D DEC+ C A +C+N PG F+C C G+ G
Sbjct: 325 NYTCRCPQGYQLDSSQLD-CVDVDECQDSPC----AQECVNTPGGFRCECWVGYEPGGPG 379
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
+GA C+DVDEC C C NTDGSF C C+ GY G C D+DE
Sbjct: 380 EGA-CQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYVLAGEDGT------QCQDVDE 430
Query: 529 CANDP-TLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C LC++ C NT G + C C G+ A +G SC
Sbjct: 431 CVGPGGPLCDS-LCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 104 bits (250), Expect = 7e-22
Identities = 78/218 (35%), Positives = 94/218 (43%), Gaps = 37/218 (16%)
Query: 297 CQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQC-RNTVG-SYTC 352
C C GS+ C CR G+ L D +C + C+ PC GG C G +YTC
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSS--PCRGGATCVLGPHGKNYTC 328
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C G ++ C D+DEC D P C A C NT G
Sbjct: 329 RCPQGY--QLDSSQLDCVDVDECQD-----------------SP-----C-AQECVNTPG 363
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW---RGD 469
F C+C GY AC D DEC LG C A C N GSF C C +G+ D
Sbjct: 364 GFRCECWVGYEPGGPGEGACQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYVLAGED 421
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
G C+DVDEC+ GG + C NT GSF C C G+
Sbjct: 422 GTQCQDVDECV-GPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 101 bits (243), Expect = 5e-21
Identities = 73/230 (31%), Positives = 95/230 (41%), Gaps = 30/230 (13%)
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPG- 306
C+ +G C E G++ C C G+ R +CV P
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
Query: 307 -SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGA 365
+Y C C +G+ L + C D+DEC PC +C NT G + C C G P G
Sbjct: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQDS--PCAQ-ECVNTPGGFRCECWVGYEPGGPG- 379
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVK 425
+ CQD+DECA L +S C G C NT GSF C C +GY +
Sbjct: 380 EGACQDVDECA-------------LGRSP-------CAQG-CTNTDGSFHCSCEEGYVLA 418
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATC 473
E G C D DEC +G + C N GSF C C GW +G +C
Sbjct: 419 GEDGTQCQDVDEC-VGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 97.5 bits (232), Expect = 1e-19
Identities = 52/128 (40%), Positives = 64/128 (50%), Gaps = 6/128 (4%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNH-TCVDVNECEIVDGVCGDGD 175
++V+EC P C C N GGF C+C+ GYE C DV+EC + C G
Sbjct: 344 VDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG- 399
Query: 176 CHNTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C NT+GSF C C GY A + C D+DEC C NT GSF C C G
Sbjct: 400 CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWV 459
Query: 235 LAPDRLSC 242
LAP+ +SC
Sbjct: 460 LAPNGVSC 467
Score = 40.7 bits (91), Expect = 0.013
Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 14/105 (13%)
Query: 466 WRGDGATCEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
W G C C NNGGCH + DGSF C C G+ R + + +C
Sbjct: 250 WGSSGPLCVSPKYGCNFNNGGCH-QDCFEGGDGSFLCGCRPGF-------RLLDDLVTCA 301
Query: 525 DIDECANDPTLCENG-HCSNTPGG--YECDCDVGFTRAADGRSCL 566
+ C++ P C G C P G Y C C G+ + C+
Sbjct: 302 SRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCV 344
>AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1, q
subcomponent, receptor 1 protein.
Length = 652
Score = 126 bits (304), Expect = 2e-28
Identities = 71/193 (36%), Positives = 88/193 (45%), Gaps = 12/193 (6%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDC-HNTEG-SFTCHCRPGYKADD 195
G F C C PG+ TC N C C G C G ++TC C GY+ D
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL-APDRLSCKDIDECSITSGI 254
CVD+DEC D+ CVNT G FRCEC G E P +C+D+DEC++
Sbjct: 339 SQLDCVDVDECQDSPC---AQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 255 CSNGACENQMGTYQCVCDEGY--AQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTC 312
C+ G C N G++ C C+EGY A C C NT GS+HC C
Sbjct: 396 CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGC 454
Query: 313 REGWHLRADGRSC 325
GW L +G SC
Sbjct: 455 LPGWVLAPNGVSC 467
Score = 124 bits (300), Expect = 6e-28
Identities = 70/210 (33%), Positives = 94/210 (44%), Gaps = 10/210 (4%)
Query: 164 CEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CV--N 220
C +G C +GSF C CRPG++ D C + C+ + CRGG CV
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGP 321
Query: 221 TAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTV 280
++ C C G +L +L C D+DEC + C+ C N G ++C C GY
Sbjct: 322 HGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGP 378
Query: 281 -KSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRA-DGRSCRDIDECAGGARPC 338
+ C C NT GS+HC+C EG+ L DG C+D+DEC G P
Sbjct: 379 GEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPL 438
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAAGAKPT 368
C NT GS+ C C G V + G T
Sbjct: 439 CDSLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
Score = 108 bits (259), Expect = 6e-23
Identities = 61/158 (38%), Positives = 79/158 (50%), Gaps = 20/158 (12%)
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR----G 468
++ C+CP GY + Q C D DEC+ C A +C+N PG F+C C G+ G
Sbjct: 325 NYTCRCPQGYQLDSSQLD-CVDVDECQDSPC----AQECVNTPGGFRCECWVGYEPGGPG 379
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
+GA C+DVDEC C C NTDGSF C C+ GY G C D+DE
Sbjct: 380 EGA-CQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYVLAGEDGT------QCQDVDE 430
Query: 529 CANDP-TLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C LC++ C NT G + C C G+ A +G SC
Sbjct: 431 CVGPGGPLCDS-LCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 104 bits (250), Expect = 7e-22
Identities = 78/218 (35%), Positives = 94/218 (43%), Gaps = 37/218 (16%)
Query: 297 CQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQC-RNTVG-SYTC 352
C C GS+ C CR G+ L D +C + C+ PC GG C G +YTC
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSS--PCRGGATCVLGPHGKNYTC 328
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C G ++ C D+DEC D P C A C NT G
Sbjct: 329 RCPQGY--QLDSSQLDCVDVDECQD-----------------SP-----C-AQECVNTPG 363
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW---RGD 469
F C+C GY AC D DEC LG C A C N GSF C C +G+ D
Sbjct: 364 GFRCECWVGYEPGGPGEGACQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYVLAGED 421
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
G C+DVDEC+ GG + C NT GSF C C G+
Sbjct: 422 GTQCQDVDECV-GPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 101 bits (243), Expect = 5e-21
Identities = 73/230 (31%), Positives = 95/230 (41%), Gaps = 30/230 (13%)
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPG- 306
C+ +G C E G++ C C G+ R +CV P
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
Query: 307 -SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGA 365
+Y C C +G+ L + C D+DEC PC +C NT G + C C G P G
Sbjct: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQDS--PCAQ-ECVNTPGGFRCECWVGYEPGGPG- 379
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVK 425
+ CQD+DECA L +S C G C NT GSF C C +GY +
Sbjct: 380 EGACQDVDECA-------------LGRSP-------CAQG-CTNTDGSFHCSCEEGYVLA 418
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATC 473
E G C D DEC +G + C N GSF C C GW +G +C
Sbjct: 419 GEDGTQCQDVDEC-VGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 97.5 bits (232), Expect = 1e-19
Identities = 52/128 (40%), Positives = 64/128 (50%), Gaps = 6/128 (4%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNH-TCVDVNECEIVDGVCGDGD 175
++V+EC P C C N GGF C+C+ GYE C DV+EC + C G
Sbjct: 344 VDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG- 399
Query: 176 CHNTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C NT+GSF C C GY A + C D+DEC C NT GSF C C G
Sbjct: 400 CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWV 459
Query: 235 LAPDRLSC 242
LAP+ +SC
Sbjct: 460 LAPNGVSC 467
Score = 40.7 bits (91), Expect = 0.013
Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 14/105 (13%)
Query: 466 WRGDGATCEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
W G C C NNGGCH + DGSF C C G+ R + + +C
Sbjct: 250 WGSSGPLCVSPKYGCNFNNGGCH-QDCFEGGDGSFLCGCRPGF-------RLLDDLVTCA 301
Query: 525 DIDECANDPTLCENG-HCSNTPGG--YECDCDVGFTRAADGRSCL 566
+ C++ P C G C P G Y C C G+ + C+
Sbjct: 302 SRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCV 344
>AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1, q
subcomponent, receptor 1 variant protein.
Length = 671
Score = 126 bits (304), Expect = 2e-28
Identities = 71/193 (36%), Positives = 88/193 (45%), Gaps = 12/193 (6%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDC-HNTEG-SFTCHCRPGYKADD 195
G F C C PG+ TC N C C G C G ++TC C GY+ D
Sbjct: 300 GSFLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQGYQLDS 357
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL-APDRLSCKDIDECSITSGI 254
CVD+DEC D+ CVNT G FRCEC G E P +C+D+DEC++
Sbjct: 358 SQLDCVDVDECQDSPC---AQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP 414
Query: 255 CSNGACENQMGTYQCVCDEGY--AQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTC 312
C+ G C N G++ C C+EGY A C C NT GS+HC C
Sbjct: 415 CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGC 473
Query: 313 REGWHLRADGRSC 325
GW L +G SC
Sbjct: 474 LPGWVLAPNGVSC 486
Score = 124 bits (300), Expect = 6e-28
Identities = 70/210 (33%), Positives = 94/210 (44%), Gaps = 10/210 (4%)
Query: 164 CEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CV--N 220
C +G C +GSF C CRPG++ D C + C+ + CRGG CV
Sbjct: 283 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGP 340
Query: 221 TAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTV 280
++ C C G +L +L C D+DEC + C+ C N G ++C C GY
Sbjct: 341 HGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGP 397
Query: 281 -KSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRA-DGRSCRDIDECAGGARPC 338
+ C C NT GS+HC+C EG+ L DG C+D+DEC G P
Sbjct: 398 GEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPL 457
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAAGAKPT 368
C NT GS+ C C G V + G T
Sbjct: 458 CDSLCFNTQGSFHCGCLPGWVLAPNGVSCT 487
Score = 108 bits (259), Expect = 6e-23
Identities = 61/158 (38%), Positives = 79/158 (50%), Gaps = 20/158 (12%)
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR----G 468
++ C+CP GY + Q C D DEC+ C A +C+N PG F+C C G+ G
Sbjct: 344 NYTCRCPQGYQLDSSQLD-CVDVDECQDSPC----AQECVNTPGGFRCECWVGYEPGGPG 398
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDE 528
+GA C+DVDEC C C NTDGSF C C+ GY G C D+DE
Sbjct: 399 EGA-CQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYVLAGEDGT------QCQDVDE 449
Query: 529 CANDP-TLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
C LC++ C NT G + C C G+ A +G SC
Sbjct: 450 CVGPGGPLCDS-LCFNTQGSFHCGCLPGWVLAPNGVSC 486
Score = 104 bits (250), Expect = 7e-22
Identities = 78/218 (35%), Positives = 94/218 (43%), Gaps = 37/218 (16%)
Query: 297 CQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQC-RNTVG-SYTC 352
C C GS+ C CR G+ L D +C + C+ PC GG C G +YTC
Sbjct: 290 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSS--PCRGGATCVLGPHGKNYTC 347
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C G ++ C D+DEC D P C A C NT G
Sbjct: 348 RCPQGY--QLDSSQLDCVDVDECQD-----------------SP-----C-AQECVNTPG 382
Query: 413 SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW---RGD 469
F C+C GY AC D DEC LG C A C N GSF C C +G+ D
Sbjct: 383 GFRCECWVGYEPGGPGEGACQDVDECALGRSPC--AQGCTNTDGSFHCSCEEGYVLAGED 440
Query: 470 GATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
G C+DVDEC+ GG + C NT GSF C C G+
Sbjct: 441 GTQCQDVDECV-GPGGPLCDSLCFNTQGSFHCGCLPGW 477
Score = 101 bits (243), Expect = 5e-21
Identities = 73/230 (31%), Positives = 95/230 (41%), Gaps = 30/230 (13%)
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPG- 306
C+ +G C E G++ C C G+ R +CV P
Sbjct: 283 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 342
Query: 307 -SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGA 365
+Y C C +G+ L + C D+DEC PC +C NT G + C C G P G
Sbjct: 343 KNYTCRCPQGYQLDSSQLDCVDVDECQDS--PCAQ-ECVNTPGGFRCECWVGYEPGGPG- 398
Query: 366 KPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVK 425
+ CQD+DECA L +S C G C NT GSF C C +GY +
Sbjct: 399 EGACQDVDECA-------------LGRSP-------CAQG-CTNTDGSFHCSCEEGYVLA 437
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW--RGDGATC 473
E G C D DEC +G + C N GSF C C GW +G +C
Sbjct: 438 GEDGTQCQDVDEC-VGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 486
Score = 97.5 bits (232), Expect = 1e-19
Identities = 52/128 (40%), Positives = 64/128 (50%), Gaps = 6/128 (4%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNH-TCVDVNECEIVDGVCGDGD 175
++V+EC P C C N GGF C+C+ GYE C DV+EC + C G
Sbjct: 363 VDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG- 418
Query: 176 CHNTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
C NT+GSF C C GY A + C D+DEC C NT GSF C C G
Sbjct: 419 CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWV 478
Query: 235 LAPDRLSC 242
LAP+ +SC
Sbjct: 479 LAPNGVSC 486
Score = 40.7 bits (91), Expect = 0.013
Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 14/105 (13%)
Query: 466 WRGDGATCEDVDE-CLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
W G C C NNGGCH + DGSF C C G+ R + + +C
Sbjct: 269 WGSSGPLCVSPKYGCNFNNGGCH-QDCFEGGDGSFLCGCRPGF-------RLLDDLVTCA 320
Query: 525 DIDECANDPTLCENG-HCSNTPGG--YECDCDVGFTRAADGRSCL 566
+ C++ P C G C P G Y C C G+ + C+
Sbjct: 321 SRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCV 363
>AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS
protein.
Length = 287
Score = 124 bits (299), Expect = 8e-28
Identities = 82/227 (36%), Positives = 106/227 (46%), Gaps = 52/227 (22%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGAR-PCGG-GQCRNTVGSYTCTCTDG 357
SCVN C C G+ ++ + DI+ECA ++ CG C NT GSY C C+ G
Sbjct: 35 SCVNATA---CRCNPGFSSFSEIITTPDINECATLSKVSCGKFSDCWNTEGSYDCVCSPG 91
Query: 358 LVPSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHN 409
P +GAK TCQD+DEC Q P LC + G+C N
Sbjct: 92 YEP-VSGAKTFKNESENTCQDVDECQ--------------------QNPRLCKSYGTCVN 130
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-- 467
T+GS+ CQC G+ D +EC G CH + C+N GS+QCRCR GW+
Sbjct: 131 TLGSYTCQCLPGFK----------DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPI 180
Query: 468 ------GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK 508
+ CEDVDEC + C C NT GS+ C C G+K
Sbjct: 181 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 227
Score = 118 bits (284), Expect = 6e-26
Identities = 74/198 (37%), Positives = 93/198 (46%), Gaps = 31/198 (15%)
Query: 143 CDCFPGYEKDSKNHTCVDVNECEIVDGV-CGD-GDCHNTEGSFTCHCRPGYK-------- 192
C C PG+ S+ T D+NEC + V CG DC NTEGS+ C C PGY+
Sbjct: 42 CRCNPGFSSFSEIITTPDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTF 101
Query: 193 ADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSIT 251
++ C D+DEC N LC+ G CVNT GS+ C+C G KD++EC+
Sbjct: 102 KNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGF---------KDVNECTSG 152
Query: 252 SGIC-SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC---QHS------C 301
C S+ C N +G+YQC C G+ Q S C QH C
Sbjct: 153 QNPCHSSTHCLNNVGSYQCRCRPGW-QPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVC 211
Query: 302 VNTPGSYHCTCREGWHLR 319
NT GSY C CR GW R
Sbjct: 212 FNTVGSYSCRCRPGWKPR 229
Score = 107 bits (258), Expect = 8e-23
Identities = 68/225 (30%), Positives = 95/225 (42%), Gaps = 29/225 (12%)
Query: 71 IWSQVGGDENGDGYG-KQWGENXXXXXXXXXXXXXXXXXXXXXXXXQMEVNECAAFPGL- 128
+W + G E D G +W ++NECA +
Sbjct: 11 VWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPDINECATLSKVS 70
Query: 129 CGH-GRCRNLLGGFTCDCFPGYE--------KDSKNHTCVDVNECEIVDGVCGD-GDCHN 178
CG C N G + C C PGYE K+ +TC DV+EC+ +C G C N
Sbjct: 71 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 130
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGG-RCVNTAGSFRCECGHGME--- 234
T GS+TC C PG+K D++EC C C+N GS++C C G +
Sbjct: 131 TLGSYTCQCLPGFK---------DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIP 181
Query: 235 ---LAPDRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGY 275
P+ C+D+DECS C S+ C N +G+Y C C G+
Sbjct: 182 GSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 226
Score = 103 bits (248), Expect = 1e-21
Identities = 70/210 (33%), Positives = 88/210 (41%), Gaps = 36/210 (17%)
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICV--DIDECADNDALCRG--GRCVNTAGSFRCE 228
D C N C C PG+ + FS+I DI+ECA + G C NT GS+ C
Sbjct: 33 DSSCVNATA---CRCNPGFSS--FSEIITTPDINECATLSKVSCGKFSDCWNTEGSYDCV 87
Query: 229 CGHGMELAP--------DRLSCKDIDECSITSGIC-SNGACENQMGTYQCVCDEGYAQST 279
C G E +C+D+DEC +C S G C N +G+Y C C G+
Sbjct: 88 CSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKDVN 147
Query: 280 VKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREGWHL------RADGRSCRDIDEC 331
C S C+N GSY C CR GW + C D+DEC
Sbjct: 148 ---------ECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDEC 198
Query: 332 AGGARPCGGGQ-CRNTVGSYTCTCTDGLVP 360
+ G C C NTVGSY+C C G P
Sbjct: 199 SSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 228
Score = 95.1 bits (226), Expect = 6e-19
Identities = 56/167 (33%), Positives = 76/167 (45%), Gaps = 23/167 (13%)
Query: 402 CGAGS-CHNTIGSFVCQCPDGY-------SVKPEQGPACTDDDECELGTCDCHPAADCIN 453
CG S C NT GS+ C C GY + K E C D DEC+ C C+N
Sbjct: 71 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 130
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYK---GD 510
GS+ C+C G++ DV+EC + CH C N GS++C C G++ G
Sbjct: 131 TLGSYTCQCLPGFK-------DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGS 183
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
G C D+DEC++ C++ C NT G Y C C G+
Sbjct: 184 PNGPNNTVCE----DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 226
Score = 76.2 bits (179), Expect = 3e-13
Identities = 51/158 (32%), Positives = 68/158 (43%), Gaps = 29/158 (18%)
Query: 411 IGSFVCQCPDGYSVKPEQGPACTDDDECE-LGTCDCHPAADCINLPGSFQCRCRDGWRG- 468
+ + C+C G+S E D +EC L C +DC N GS+ C C G+
Sbjct: 37 VNATACRCNPGFSSFSEI-ITTPDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPV 95
Query: 469 DGA---------TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
GA TC+DVDEC N C TC NT GS+ C C G+K
Sbjct: 96 SGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK----------- 144
Query: 520 VYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVGF 556
D++EC + C + HC N G Y+C C G+
Sbjct: 145 -----DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 177
Score = 75.4 bits (177), Expect = 5e-13
Identities = 42/118 (35%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 445 CHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLT-NNGGCHPRATCANTDGSFRC 501
C + C+N CRC G+ + T D++EC T + C + C NT+GS+ C
Sbjct: 30 CPQDSSCVNATA---CRCNPGFSSFSEIITTPDINECATLSKVSCGKFSDCWNTEGSYDC 86
Query: 502 LCDTGYKGDGYGLRTVC--CVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
+C GY+ G +T +C D+DEC +P LC++ G C NT G Y C C GF
Sbjct: 87 VCSPGYEPVS-GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGF 143
>AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein.
Length = 1176
Score = 123 bits (296), Expect = 2e-27
Identities = 116/398 (29%), Positives = 168/398 (42%), Gaps = 58/398 (14%)
Query: 145 CFPGYE---KDSKNHTCVDVNECEIVDGVCGDGDCHNTEG----SFTCHCRPGYKADDFS 197
C PG E +S +TC + C G +G F C+C PG++
Sbjct: 47 CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPNGFRCYCVPGFQGP--- 103
Query: 198 KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECSITSGICS 256
+ +DIDECA G C N A + C C G ++C+ ++DEC+ S C
Sbjct: 104 RCELDIDECASRPCH-HGATCRNLADRYECHCPLGYA----GVTCETEVDECA--SAPCL 156
Query: 257 NGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREG 315
+GA C + +G+++CVC GY + + H VN + C C
Sbjct: 157 HGASCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVN---GFRCDCAGT 213
Query: 316 WHLRADGRSC-RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DI 372
+ +G C R++ ECA PC C +GS+ C C G + C+ D
Sbjct: 214 GY---EGTHCEREVLECASA--PCEHNASCLEGLGSFRCLCWPGY------SGELCEVDE 262
Query: 373 DECADLI----STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQ 428
DECA + S L V P GA S + G F+C CP G+ +
Sbjct: 263 DECASSPCQHGGRCLQRSDPALYGGVQAAFP---GAFSFRHAAG-FLCHCPPGF-----E 313
Query: 429 GPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTNNGGC 486
G C + DEC + C C +LP FQC C DG+ G TC EDVDECL++ C
Sbjct: 314 GADCGVEVDEC--ASRPCLNGGHCQDLPNGFQCHCPDGYA--GPTCEEDVDECLSD--PC 367
Query: 487 HPRATCANTDGSFRCLCDTGYKGDGYGLR-TVCCVYSC 523
TC++T + C C + G ++ T C ++C
Sbjct: 368 LHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTC 405
Score = 114 bits (274), Expect = 9e-25
Identities = 118/419 (28%), Positives = 158/419 (37%), Gaps = 56/419 (13%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLG----GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
ME CA P C HG G GF C C PG++ +D++EC C
Sbjct: 66 MEPRGCATQP--CHHGALCVPQGPDPNGFRCYCVPGFQGPRCE---LDIDEC--ASRPCH 118
Query: 173 DG-DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
G C N + CHC GY ++DECA L G C++ GSFRC C
Sbjct: 119 HGATCRNLADRYECHCPLGYAGVTCE---TEVDECASAPCL-HGASCLDGVGSFRCVCAP 174
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
G +L D+DEC + G C + + ++C C A + +
Sbjct: 175 GYGGTRCQL---DLDECQ-SQPCAHGGTCHDLVNGFRCDC----AGTGYEGTHCEREVLE 226
Query: 292 XXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTV 347
C+H SC+ GS+ C C G+ G C D DECA + PC GG+C
Sbjct: 227 CASAPCEHNASCLEGLGSFRCLCWPGY----SGELCEVDEDECA--SSPCQHGGRCLQRS 280
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDEC-ADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
P A + + C + VDE P L G G
Sbjct: 281 DPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASR-----PCLNG-GH 334
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDG 465
C + F C CPDGY+ GP C +D DEC C H C + + CRC +
Sbjct: 335 CQDLPNGFQCHCPDGYA-----GPTCEEDVDECLSDPC-LH-GGTCSDTVAGYICRCPET 387
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATC----ANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
W G + + + C + C ATC + S+ C C G G G T V
Sbjct: 388 WGGRDCSVQ-LTGCQGHT--CPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSV 443
Score = 109 bits (262), Expect = 3e-23
Identities = 111/384 (28%), Positives = 166/384 (43%), Gaps = 88/384 (22%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGD 173
+++++ECA+ P C HG CRNL + C C GY TC +V+EC + G
Sbjct: 106 ELDIDECASRP--CHHGATCRNLADRYECHCPLGY----AGVTCETEVDECASAPCLHG- 158
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHG 232
C + GSF C C PGY ++ +D+DEC + GG C + FRC+C G G
Sbjct: 159 ASCLDGVGSFRCVCAPGYGG---TRCQLDLDEC-QSQPCAHGGTCHDLVNGFRCDCAGTG 214
Query: 233 MELAPDRLSC-KDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVK-SHXXXXXX 289
E C +++ EC+ S C N +C +G+++C+C GY+ +
Sbjct: 215 YE----GTHCEREVLECA--SAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASS 268
Query: 290 XXXXXXRC-QHS--------CVNTPGSYH--------CTCREGWHLRADGRSCR-DIDEC 331
RC Q S PG++ C C G+ +G C ++DEC
Sbjct: 269 PCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF----EGADCGVEVDEC 324
Query: 332 AGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDE 389
A +RPC GG C++ + C C DG A PTC +D+DEC
Sbjct: 325 A--SRPCLNGGHCQDLPNGFQCHCPDGY------AGPTCEEDVDECLS------------ 364
Query: 390 LQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
DP + G+C +T+ ++C+CP+ + G C+ C+ TC A
Sbjct: 365 -----DPCL----HGGTCSDTVAGYICRCPETWG-----GRDCSVQLTGCQGHTCPL--A 408
Query: 449 ADCINL----PGSFQCRCRDGWRG 468
A CI + S+ C C G G
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHG 432
Score = 91.1 bits (216), Expect = 1e-17
Identities = 85/287 (29%), Positives = 116/287 (40%), Gaps = 60/287 (20%)
Query: 305 PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSA 362
P + C C G+ G C DIDECA +RPC G CRN Y C C G
Sbjct: 89 PNGFRCYCVPGFQ----GPRCELDIDECA--SRPCHHGATCRNLADRYECHCPLGYAGVT 142
Query: 363 AG------AKPTCQDIDECADLISTIIMMSVD-----ELQKSVDPQIPELCG-AGSCHNT 410
A C C D + + + Q +D + C G+CH+
Sbjct: 143 CETEVDECASAPCLHGASCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDL 202
Query: 411 IGSFVCQCPD-GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD 469
+ F C C GY +G C + + E + C A C+ GSF+C C G+ G+
Sbjct: 203 VNGFRCDCAGTGY-----EGTHC-EREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGE 256
Query: 470 GATCE-DVDECLTN----NGGCHPRATCANTDG---------SFR------CLCDTGYKG 509
CE D DEC ++ G C R+ A G SFR C C G++G
Sbjct: 257 --LCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEG 314
Query: 510 DGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
G V++DECA+ P L GHC + P G++C C G+
Sbjct: 315 ADCG----------VEVDECASRPCL-NGGHCQDLPNGFQCHCPDGY 350
Score = 81.4 bits (192), Expect = 8e-15
Identities = 89/296 (30%), Positives = 117/296 (39%), Gaps = 68/296 (22%)
Query: 297 CQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTC 352
C H +C N Y C C G+ G +C ++DECA PC G C + VGS+ C
Sbjct: 117 CHHGATCRNLADRYECHCPLGYA----GVTCETEVDECASA--PCLHGASCLDGVGSFRC 170
Query: 353 TCTDG-------LVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPEL-CGA 404
C G L ++P C C DL++ + + L C +
Sbjct: 171 VCAPGYGGTRCQLDLDECQSQP-CAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECAS 229
Query: 405 GSC-HNT-----IGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCD----CHPAADCI- 452
C HN +GSF C C GYS G C D+DEC C C +D
Sbjct: 230 APCEHNASCLEGLGSFRCLCWPGYS-----GELCEVDEDECASSPCQHGGRCLQRSDPAL 284
Query: 453 ------NLPGSFQ--------CRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDG 497
PG+F C C G+ +GA C +VDEC + C C +
Sbjct: 285 YGGVQAAFPGAFSFRHAAGFLCHCPPGF--EGADCGVEVDECASRP--CLNGGHCQDLPN 340
Query: 498 SFRCLCDTGYKGDGYGLRTVCCVYSCV-DIDECANDPTLCENGHCSNTPGGYECDC 552
F+C C GY G +C D+DEC +DP L G CS+T GY C C
Sbjct: 341 GFQCHCPDGYAGP-----------TCEEDVDECLSDPCL-HGGTCSDTVAGYICRC 384
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 7/68 (10%)
Query: 126 PGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH-NTEGSF 183
P C H G CR+L F C C PG+E V+ C C G CH + +G F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCE---AHVDPCH--SAPCARGRCHTHPDGRF 1116
Query: 184 TCHCRPGY 191
C C PG+
Sbjct: 1117 ECRCPPGF 1124
Score = 39.9 bits (89), Expect = 0.024
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 9/80 (11%)
Query: 432 CTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRA 490
C C C H A C +L +F C C GW +G CE VD C ++ C R
Sbjct: 1054 CRGAPVCAPSPC-LHDGA-CRDLFDAFACACGPGW--EGPRCEAHVDPC--HSAPC-ARG 1106
Query: 491 TC-ANTDGSFRCLCDTGYKG 509
C + DG F C C G+ G
Sbjct: 1107 RCHTHPDGRFECRCPPGFGG 1126
Score = 37.1 bits (82), Expect = 0.17
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 6/61 (9%)
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC-VNTAGSFRCECGH 231
DG C + +F C C PG++ + +D C + A C GRC + G F C C
Sbjct: 1068 DGACRDLFDAFACACGPGWEG---PRCEAHVDPC--HSAPCARGRCHTHPDGRFECRCPP 1122
Query: 232 G 232
G
Sbjct: 1123 G 1123
Score = 37.1 bits (82), Expect = 0.17
Identities = 25/76 (32%), Positives = 31/76 (40%), Gaps = 14/76 (18%)
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPAC------TDDDECELGTCDCHPAA--DCINLPG 456
G+C + +F C C G+ +GP C C G C HP +C PG
Sbjct: 1069 GACRDLFDAFACACGPGW-----EGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPG 1123
Query: 457 SFQCRCR-DGWRGDGA 471
RCR DGW G A
Sbjct: 1124 FGGPRCRWDGWAGGWA 1139
Score = 34.3 bits (75), Expect = 1.2
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 200 CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECSITSGICSNG 258
C CA + L G C + +F C CG G E P C+ +D C S C+ G
Sbjct: 1054 CRGAPVCAPSPCL-HDGACRDLFDAFACACGPGWE-GP---RCEAHVDPCH--SAPCARG 1106
Query: 259 ACENQM-GTYQCVCDEGY 275
C G ++C C G+
Sbjct: 1107 RCHTHPDGRFECRCPPGF 1124
Score = 33.5 bits (73), Expect = 2.0
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 8/69 (11%)
Query: 393 SVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
S D P+ C G+C T F C CP ++ GP C C G C P A C
Sbjct: 807 SEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT-----GPTCAQQLWCP-GQ-PCLPPATC 859
Query: 452 INLPGSFQC 460
+P F C
Sbjct: 860 EEVPDGFVC 868
Score = 33.1 bits (72), Expect = 2.7
Identities = 24/95 (25%), Positives = 35/95 (36%), Gaps = 9/95 (9%)
Query: 240 LSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
L C+ C+ S +GAC + + C C G+ ++H RC
Sbjct: 1052 LGCRGAPVCA-PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCH- 1109
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG 334
+ G + C C G+ G CR D AGG
Sbjct: 1110 --THPDGRFECRCPPGF----GGPRCR-WDGWAGG 1137
>AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2
precursor protein.
Length = 1285
Score = 122 bits (294), Expect = 3e-27
Identities = 113/397 (28%), Positives = 167/397 (42%), Gaps = 56/397 (14%)
Query: 145 CFPGYE---KDSKNHTCVDVNECEIVDGVCGDGDCHNTEG----SFTCHCRPGYKADDFS 197
C PG E +S +TC + C G +G F C+C PG++
Sbjct: 47 CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGP--- 103
Query: 198 KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECSITSGICS 256
+ +DIDECA G C N A + C C G ++C+ ++DEC+ ++
Sbjct: 104 RCELDIDECASRPCH-HGATCRNLADRYECHCPLGYA----GVTCEMEVDECA-SAPCLH 157
Query: 257 NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGW 316
G+C + +G+++CVC GY + + H VN + C C
Sbjct: 158 GGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVN---GFRCDCAGTG 214
Query: 317 HLRADGRSC-RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DID 373
+ +G C R++ ECA PC C +GS+ C C G + C+ D D
Sbjct: 215 Y---EGTHCEREVLECASA--PCEHNASCLEGLGSFRCLCWPGY------SGELCEVDED 263
Query: 374 ECADLI----STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQG 429
ECA + S L V P GA S + G F+C CP G+ +G
Sbjct: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFP---GAFSFRHAAG-FLCHCPPGF-----EG 314
Query: 430 PAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTNNGGCH 487
C + DEC + C C +LP FQC C DG+ G TC EDVDECL++ C
Sbjct: 315 ADCGVEVDEC--ASRPCLNGGHCQDLPNGFQCHCPDGYA--GPTCEEDVDECLSD--PCL 368
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLR-TVCCVYSC 523
TC++T + C C + G ++ T C ++C
Sbjct: 369 HGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTC 405
Score = 117 bits (281), Expect = 1e-25
Identities = 119/419 (28%), Positives = 160/419 (38%), Gaps = 56/419 (13%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLG----GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
ME CA P C HG G GF C C PG++ +D++EC C
Sbjct: 66 MEPRGCATQP--CHHGALCVPQGPDPTGFRCYCVPGFQGPRCE---LDIDEC--ASRPCH 118
Query: 173 DG-DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
G C N + CHC GY +++DECA L GG C++ GSFRC C
Sbjct: 119 HGATCRNLADRYECHCPLGYAGVTCE---MEVDECASAPCL-HGGSCLDGVGSFRCVCAP 174
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
G +L D+DEC + G C + + ++C C A + +
Sbjct: 175 GYGGTRCQL---DLDECQ-SQPCAHGGTCHDLVNGFRCDC----AGTGYEGTHCEREVLE 226
Query: 292 XXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTV 347
C+H SC+ GS+ C C G+ G C D DECA + PC GG+C
Sbjct: 227 CASAPCEHNASCLEGLGSFRCLCWPGY----SGELCEVDEDECA--SSPCQHGGRCLQRS 280
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDEC-ADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
P A + + C + VDE P L G G
Sbjct: 281 DPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASR-----PCLNG-GH 334
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDG 465
C + F C CPDGY+ GP C +D DEC C H C + + CRC +
Sbjct: 335 CQDLPNGFQCHCPDGYA-----GPTCEEDVDECLSDPC-LH-GGTCSDTVAGYICRCPET 387
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATC----ANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
W G + + + C + C ATC + S+ C C G G G T V
Sbjct: 388 WGGRDCSVQ-LTGCQGHT--CPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSV 443
Score = 112 bits (269), Expect = 4e-24
Identities = 112/384 (29%), Positives = 168/384 (43%), Gaps = 88/384 (22%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGD 173
+++++ECA+ P C HG CRNL + C C GY TC ++V+EC + G
Sbjct: 106 ELDIDECASRP--CHHGATCRNLADRYECHCPLGY----AGVTCEMEVDECASAPCLHG- 158
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHG 232
G C + GSF C C PGY ++ +D+DEC + GG C + FRC+C G G
Sbjct: 159 GSCLDGVGSFRCVCAPGYGG---TRCQLDLDEC-QSQPCAHGGTCHDLVNGFRCDCAGTG 214
Query: 233 MELAPDRLSC-KDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVK-SHXXXXXX 289
E C +++ EC+ S C N +C +G+++C+C GY+ +
Sbjct: 215 YE----GTHCEREVLECA--SAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASS 268
Query: 290 XXXXXXRC-QHS--------CVNTPGSYH--------CTCREGWHLRADGRSCR-DIDEC 331
RC Q S PG++ C C G+ +G C ++DEC
Sbjct: 269 PCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF----EGADCGVEVDEC 324
Query: 332 AGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDE 389
A +RPC GG C++ + C C DG A PTC +D+DEC
Sbjct: 325 A--SRPCLNGGHCQDLPNGFQCHCPDGY------AGPTCEEDVDECLS------------ 364
Query: 390 LQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
DP + G+C +T+ ++C+CP+ + G C+ C+ TC A
Sbjct: 365 -----DPCL----HGGTCSDTVAGYICRCPETWG-----GRDCSVQLTGCQGHTCPL--A 408
Query: 449 ADCINL----PGSFQCRCRDGWRG 468
A CI + S+ C C G G
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHG 432
Score = 92.7 bits (220), Expect = 3e-18
Identities = 88/286 (30%), Positives = 120/286 (41%), Gaps = 78/286 (27%)
Query: 297 CQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTC 352
C H +C N Y C C G+ G +C ++DECA PC GG C + VGS+ C
Sbjct: 117 CHHGATCRNLADRYECHCPLGYA----GVTCEMEVDECASA--PCLHGGSCLDGVGSFRC 170
Query: 353 TCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
C P G + CQ D+DEC Q G+CH+ +
Sbjct: 171 VCA----PGYGGTR--CQLDLDEC---------------------QSQPCAHGGTCHDLV 203
Query: 412 GSFVCQCPD-GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
F C C GY +G C + + E + C A C+ GSF+C C G+ G+
Sbjct: 204 NGFRCDCAGTGY-----EGTHC-EREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGE- 256
Query: 471 ATCE-DVDECLTN----NGGCHPRATCANTDG---------SFR------CLCDTGYKGD 510
CE D DEC ++ G C R+ A G SFR C C G++G
Sbjct: 257 -LCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
G V++DECA+ P L GHC + P G++C C G+
Sbjct: 316 DCG----------VEVDECASRPCL-NGGHCQDLPNGFQCHCPDGY 350
Score = 62.1 bits (144), Expect = 5e-09
Identities = 45/154 (29%), Positives = 64/154 (41%), Gaps = 14/154 (9%)
Query: 126 PGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH-NTEGSF 183
P C H G CR+L F C C PG+E V+ C C G CH + +G F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCE---AHVDPCH--SAPCARGRCHTHPDGRF 1116
Query: 184 TCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK 243
C C PG+ ++ V EC+ N G C + + C C G LA R C+
Sbjct: 1117 ECRCPPGF-GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG--LAGQR--CQ 1171
Query: 244 DIDECSITSGICSN-GACENQMGTYQCVCDEGYA 276
+ + C N G C G +C+C+ ++
Sbjct: 1172 -VPTLPCEANPCLNGGTCRAAGGVSECICNARFS 1204
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/120 (28%), Positives = 44/120 (36%), Gaps = 13/120 (10%)
Query: 394 VDPQIPELCGAGSCH-NTIGSFVCQCPDGYSVKPEQGPAC---TDDDECELGTCDCHPAA 449
VDP C G CH + G F C+CP G+ GP C EC L C +
Sbjct: 1095 VDPCHSAPCARGRCHTHPDGRFECRCPPGFG-----GPRCRLPVPSKECSLNVT-CLDGS 1148
Query: 450 DCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
C + C C +G G + C N C TC G C+C+ + G
Sbjct: 1149 PCEGGSPAANCSCLEGLAGQRCQVPTLP-CEANP--CLNGGTCRAAGGVSECICNARFSG 1205
Score = 46.8 bits (106), Expect = 2e-04
Identities = 40/157 (25%), Positives = 57/157 (36%), Gaps = 25/157 (15%)
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTC---DCHPAADCINLPGSFQC 460
G+C + +F C C G+ +GP C D C C CH D G F+C
Sbjct: 1069 GACRDLFDAFACACGPGW-----EGPRCEAHVDPCHSAPCARGRCHTHPD-----GRFEC 1118
Query: 461 RCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
RC G+ G + + N C + C + C C G G + T+ C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC- 1177
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
+ + C N G C G EC C+ F+
Sbjct: 1178 ----EANPCLN------GGTCRAAGGVSECICNARFS 1204
Score = 41.5 bits (93), Expect = 0.008
Identities = 36/123 (29%), Positives = 46/123 (37%), Gaps = 17/123 (13%)
Query: 432 CTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRA 490
C C C H A C +L +F C C GW +G CE VD C ++ C R
Sbjct: 1054 CRGAPVCAPSPC-LHDGA-CRDLFDAFACACGPGW--EGPRCEAHVDPC--HSAPC-ARG 1106
Query: 491 TC-ANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYE 549
C + DG F C C G+ G L V EC+ + T + C
Sbjct: 1107 RCHTHPDGRFECRCPPGFGGPRCRLP--------VPSKECSLNVTCLDGSPCEGGSPAAN 1158
Query: 550 CDC 552
C C
Sbjct: 1159 CSC 1161
Score = 40.7 bits (91), Expect = 0.013
Identities = 28/122 (22%), Positives = 43/122 (35%), Gaps = 11/122 (9%)
Query: 240 LSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
L C+ C+ S +GAC + + C C G+ ++H RC
Sbjct: 1052 LGCRGAPVCA-PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCH- 1109
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCR---DIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
+ G + C C G+ G CR EC+ G C + C+C +
Sbjct: 1110 --THPDGRFECRCPPGF----GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLE 1163
Query: 357 GL 358
GL
Sbjct: 1164 GL 1165
Score = 33.5 bits (73), Expect = 2.0
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 8/69 (11%)
Query: 393 SVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
S D P+ C G+C T F C CP ++ GP C C G C P A C
Sbjct: 807 SEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT-----GPTCAQQLWCP-GQ-PCLPPATC 859
Query: 452 INLPGSFQC 460
+P F C
Sbjct: 860 EEVPDGFVC 868
>AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 122 bits (294), Expect = 3e-27
Identities = 113/397 (28%), Positives = 167/397 (42%), Gaps = 56/397 (14%)
Query: 145 CFPGYE---KDSKNHTCVDVNECEIVDGVCGDGDCHNTEG----SFTCHCRPGYKADDFS 197
C PG E +S +TC + C G +G F C+C PG++
Sbjct: 47 CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGP--- 103
Query: 198 KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECSITSGICS 256
+ +DIDECA G C N A + C C G ++C+ ++DEC+ ++
Sbjct: 104 RCELDIDECASRPCH-HGATCRNLADRYECHCPLGYA----GVTCEMEVDECA-SAPCLH 157
Query: 257 NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGW 316
G+C + +G+++CVC GY + + H VN + C C
Sbjct: 158 GGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVN---GFRCDCAGTG 214
Query: 317 HLRADGRSC-RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DID 373
+ +G C R++ ECA PC C +GS+ C C G + C+ D D
Sbjct: 215 Y---EGTHCEREVLECASA--PCEHNASCLEGLGSFRCLCWPGY------SGELCEVDED 263
Query: 374 ECADLI----STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQG 429
ECA + S L V P GA S + G F+C CP G+ +G
Sbjct: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFP---GAFSFRHAAG-FLCHCPPGF-----EG 314
Query: 430 PAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTNNGGCH 487
C + DEC + C C +LP FQC C DG+ G TC EDVDECL++ C
Sbjct: 315 ADCGVEVDEC--ASRPCLNGGHCQDLPNGFQCHCPDGYA--GPTCEEDVDECLSD--PCL 368
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLR-TVCCVYSC 523
TC++T + C C + G ++ T C ++C
Sbjct: 369 HGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTC 405
Score = 117 bits (281), Expect = 1e-25
Identities = 119/419 (28%), Positives = 160/419 (38%), Gaps = 56/419 (13%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLG----GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
ME CA P C HG G GF C C PG++ +D++EC C
Sbjct: 66 MEPRGCATQP--CHHGALCVPQGPDPTGFRCYCVPGFQGPRCE---LDIDEC--ASRPCH 118
Query: 173 DG-DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
G C N + CHC GY +++DECA L GG C++ GSFRC C
Sbjct: 119 HGATCRNLADRYECHCPLGYAGVTCE---MEVDECASAPCL-HGGSCLDGVGSFRCVCAP 174
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
G +L D+DEC + G C + + ++C C A + +
Sbjct: 175 GYGGTRCQL---DLDECQ-SQPCAHGGTCHDLVNGFRCDC----AGTGYEGTHCEREVLE 226
Query: 292 XXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTV 347
C+H SC+ GS+ C C G+ G C D DECA + PC GG+C
Sbjct: 227 CASAPCEHNASCLEGLGSFRCLCWPGY----SGELCEVDEDECA--SSPCQHGGRCLQRS 280
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDEC-ADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
P A + + C + VDE P L G G
Sbjct: 281 DPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASR-----PCLNG-GH 334
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDG 465
C + F C CPDGY+ GP C +D DEC C H C + + CRC +
Sbjct: 335 CQDLPNGFQCHCPDGYA-----GPTCEEDVDECLSDPC-LH-GGTCSDTVAGYICRCPET 387
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATC----ANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
W G + + + C + C ATC + S+ C C G G G T V
Sbjct: 388 WGGRDCSVQ-LTGCQGHT--CPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSV 443
Score = 112 bits (269), Expect = 4e-24
Identities = 112/384 (29%), Positives = 168/384 (43%), Gaps = 88/384 (22%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGD 173
+++++ECA+ P C HG CRNL + C C GY TC ++V+EC + G
Sbjct: 106 ELDIDECASRP--CHHGATCRNLADRYECHCPLGY----AGVTCEMEVDECASAPCLHG- 158
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHG 232
G C + GSF C C PGY ++ +D+DEC + GG C + FRC+C G G
Sbjct: 159 GSCLDGVGSFRCVCAPGYGG---TRCQLDLDEC-QSQPCAHGGTCHDLVNGFRCDCAGTG 214
Query: 233 MELAPDRLSC-KDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVK-SHXXXXXX 289
E C +++ EC+ S C N +C +G+++C+C GY+ +
Sbjct: 215 YE----GTHCEREVLECA--SAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASS 268
Query: 290 XXXXXXRC-QHS--------CVNTPGSYH--------CTCREGWHLRADGRSCR-DIDEC 331
RC Q S PG++ C C G+ +G C ++DEC
Sbjct: 269 PCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF----EGADCGVEVDEC 324
Query: 332 AGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDE 389
A +RPC GG C++ + C C DG A PTC +D+DEC
Sbjct: 325 A--SRPCLNGGHCQDLPNGFQCHCPDGY------AGPTCEEDVDECLS------------ 364
Query: 390 LQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
DP + G+C +T+ ++C+CP+ + G C+ C+ TC A
Sbjct: 365 -----DPCL----HGGTCSDTVAGYICRCPETWG-----GRDCSVQLTGCQGHTCPL--A 408
Query: 449 ADCINL----PGSFQCRCRDGWRG 468
A CI + S+ C C G G
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHG 432
Score = 92.7 bits (220), Expect = 3e-18
Identities = 88/286 (30%), Positives = 120/286 (41%), Gaps = 78/286 (27%)
Query: 297 CQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTC 352
C H +C N Y C C G+ G +C ++DECA PC GG C + VGS+ C
Sbjct: 117 CHHGATCRNLADRYECHCPLGYA----GVTCEMEVDECASA--PCLHGGSCLDGVGSFRC 170
Query: 353 TCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
C P G + CQ D+DEC Q G+CH+ +
Sbjct: 171 VCA----PGYGGTR--CQLDLDEC---------------------QSQPCAHGGTCHDLV 203
Query: 412 GSFVCQCPD-GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
F C C GY +G C + + E + C A C+ GSF+C C G+ G+
Sbjct: 204 NGFRCDCAGTGY-----EGTHC-EREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGE- 256
Query: 471 ATCE-DVDECLTN----NGGCHPRATCANTDG---------SFR------CLCDTGYKGD 510
CE D DEC ++ G C R+ A G SFR C C G++G
Sbjct: 257 -LCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
G V++DECA+ P L GHC + P G++C C G+
Sbjct: 316 DCG----------VEVDECASRPCL-NGGHCQDLPNGFQCHCPDGY 350
Score = 62.1 bits (144), Expect = 5e-09
Identities = 45/154 (29%), Positives = 64/154 (41%), Gaps = 14/154 (9%)
Query: 126 PGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH-NTEGSF 183
P C H G CR+L F C C PG+E V+ C C G CH + +G F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCE---AHVDPCH--SAPCARGRCHTHPDGRF 1116
Query: 184 TCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK 243
C C PG+ ++ V EC+ N G C + + C C G LA R C+
Sbjct: 1117 ECRCPPGF-GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG--LAGQR--CQ 1171
Query: 244 DIDECSITSGICSN-GACENQMGTYQCVCDEGYA 276
+ + C N G C G +C+C+ ++
Sbjct: 1172 -VPTLPCEANPCLNGGTCRAAGGVSECICNARFS 1204
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/120 (28%), Positives = 44/120 (36%), Gaps = 13/120 (10%)
Query: 394 VDPQIPELCGAGSCH-NTIGSFVCQCPDGYSVKPEQGPAC---TDDDECELGTCDCHPAA 449
VDP C G CH + G F C+CP G+ GP C EC L C +
Sbjct: 1095 VDPCHSAPCARGRCHTHPDGRFECRCPPGFG-----GPRCRLPVPSKECSLNVT-CLDGS 1148
Query: 450 DCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
C + C C +G G + C N C TC G C+C+ + G
Sbjct: 1149 PCEGGSPAANCSCLEGLAGQRCQVPTLP-CEANP--CLNGGTCRAAGGVSECICNARFSG 1205
Score = 46.8 bits (106), Expect = 2e-04
Identities = 40/157 (25%), Positives = 57/157 (36%), Gaps = 25/157 (15%)
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTC---DCHPAADCINLPGSFQC 460
G+C + +F C C G+ +GP C D C C CH D G F+C
Sbjct: 1069 GACRDLFDAFACACGPGW-----EGPRCEAHVDPCHSAPCARGRCHTHPD-----GRFEC 1118
Query: 461 RCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
RC G+ G + + N C + C + C C G G + T+ C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC- 1177
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
+ + C N G C G EC C+ F+
Sbjct: 1178 ----EANPCLN------GGTCRAAGGVSECICNARFS 1204
Score = 41.5 bits (93), Expect = 0.008
Identities = 36/123 (29%), Positives = 46/123 (37%), Gaps = 17/123 (13%)
Query: 432 CTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRA 490
C C C H A C +L +F C C GW +G CE VD C ++ C R
Sbjct: 1054 CRGAPVCAPSPC-LHDGA-CRDLFDAFACACGPGW--EGPRCEAHVDPC--HSAPC-ARG 1106
Query: 491 TC-ANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYE 549
C + DG F C C G+ G L V EC+ + T + C
Sbjct: 1107 RCHTHPDGRFECRCPPGFGGPRCRLP--------VPSKECSLNVTCLDGSPCEGGSPAAN 1158
Query: 550 CDC 552
C C
Sbjct: 1159 CSC 1161
Score = 40.7 bits (91), Expect = 0.013
Identities = 28/122 (22%), Positives = 43/122 (35%), Gaps = 11/122 (9%)
Query: 240 LSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
L C+ C+ S +GAC + + C C G+ ++H RC
Sbjct: 1052 LGCRGAPVCA-PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCH- 1109
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCR---DIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
+ G + C C G+ G CR EC+ G C + C+C +
Sbjct: 1110 --THPDGRFECRCPPGF----GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLE 1163
Query: 357 GL 358
GL
Sbjct: 1164 GL 1165
Score = 33.5 bits (73), Expect = 2.0
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 8/69 (11%)
Query: 393 SVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
S D P+ C G+C T F C CP ++ GP C C G C P A C
Sbjct: 807 SEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT-----GPTCAQQLWCP-GQ-PCLPPATC 859
Query: 452 INLPGSFQC 460
+P F C
Sbjct: 860 EEVPDGFVC 868
>AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 122 bits (294), Expect = 3e-27
Identities = 113/397 (28%), Positives = 167/397 (42%), Gaps = 56/397 (14%)
Query: 145 CFPGYE---KDSKNHTCVDVNECEIVDGVCGDGDCHNTEG----SFTCHCRPGYKADDFS 197
C PG E +S +TC + C G +G F C+C PG++
Sbjct: 47 CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGP--- 103
Query: 198 KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECSITSGICS 256
+ +DIDECA G C N A + C C G ++C+ ++DEC+ ++
Sbjct: 104 RCELDIDECASRPCH-HGATCRNLADRYECHCPLGYA----GVTCEMEVDECA-SAPCLH 157
Query: 257 NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGW 316
G+C + +G+++CVC GY + + H VN + C C
Sbjct: 158 GGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVN---GFRCDCAGTG 214
Query: 317 HLRADGRSC-RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DID 373
+ +G C R++ ECA PC C +GS+ C C G + C+ D D
Sbjct: 215 Y---EGTHCEREVLECASA--PCEHNASCLEGLGSFRCLCWPGY------SGELCEVDED 263
Query: 374 ECADLI----STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQG 429
ECA + S L V P GA S + G F+C CP G+ +G
Sbjct: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFP---GAFSFRHAAG-FLCHCPPGF-----EG 314
Query: 430 PAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTNNGGCH 487
C + DEC + C C +LP FQC C DG+ G TC EDVDECL++ C
Sbjct: 315 ADCGVEVDEC--ASRPCLNGGHCQDLPNGFQCHCPDGYA--GPTCEEDVDECLSD--PCL 368
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLR-TVCCVYSC 523
TC++T + C C + G ++ T C ++C
Sbjct: 369 HGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTC 405
Score = 117 bits (281), Expect = 1e-25
Identities = 119/419 (28%), Positives = 160/419 (38%), Gaps = 56/419 (13%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLG----GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
ME CA P C HG G GF C C PG++ +D++EC C
Sbjct: 66 MEPRGCATQP--CHHGALCVPQGPDPTGFRCYCVPGFQGPRCE---LDIDEC--ASRPCH 118
Query: 173 DG-DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
G C N + CHC GY +++DECA L GG C++ GSFRC C
Sbjct: 119 HGATCRNLADRYECHCPLGYAGVTCE---MEVDECASAPCL-HGGSCLDGVGSFRCVCAP 174
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
G +L D+DEC + G C + + ++C C A + +
Sbjct: 175 GYGGTRCQL---DLDECQ-SQPCAHGGTCHDLVNGFRCDC----AGTGYEGTHCEREVLE 226
Query: 292 XXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTV 347
C+H SC+ GS+ C C G+ G C D DECA + PC GG+C
Sbjct: 227 CASAPCEHNASCLEGLGSFRCLCWPGY----SGELCEVDEDECA--SSPCQHGGRCLQRS 280
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDEC-ADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
P A + + C + VDE P L G G
Sbjct: 281 DPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASR-----PCLNG-GH 334
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDG 465
C + F C CPDGY+ GP C +D DEC C H C + + CRC +
Sbjct: 335 CQDLPNGFQCHCPDGYA-----GPTCEEDVDECLSDPC-LH-GGTCSDTVAGYICRCPET 387
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATC----ANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
W G + + + C + C ATC + S+ C C G G G T V
Sbjct: 388 WGGRDCSVQ-LTGCQGHT--CPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSV 443
Score = 112 bits (269), Expect = 4e-24
Identities = 112/384 (29%), Positives = 168/384 (43%), Gaps = 88/384 (22%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGD 173
+++++ECA+ P C HG CRNL + C C GY TC ++V+EC + G
Sbjct: 106 ELDIDECASRP--CHHGATCRNLADRYECHCPLGY----AGVTCEMEVDECASAPCLHG- 158
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHG 232
G C + GSF C C PGY ++ +D+DEC + GG C + FRC+C G G
Sbjct: 159 GSCLDGVGSFRCVCAPGYGG---TRCQLDLDEC-QSQPCAHGGTCHDLVNGFRCDCAGTG 214
Query: 233 MELAPDRLSC-KDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVK-SHXXXXXX 289
E C +++ EC+ S C N +C +G+++C+C GY+ +
Sbjct: 215 YE----GTHCEREVLECA--SAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASS 268
Query: 290 XXXXXXRC-QHS--------CVNTPGSYH--------CTCREGWHLRADGRSCR-DIDEC 331
RC Q S PG++ C C G+ +G C ++DEC
Sbjct: 269 PCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF----EGADCGVEVDEC 324
Query: 332 AGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDE 389
A +RPC GG C++ + C C DG A PTC +D+DEC
Sbjct: 325 A--SRPCLNGGHCQDLPNGFQCHCPDGY------AGPTCEEDVDECLS------------ 364
Query: 390 LQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
DP + G+C +T+ ++C+CP+ + G C+ C+ TC A
Sbjct: 365 -----DPCL----HGGTCSDTVAGYICRCPETWG-----GRDCSVQLTGCQGHTCPL--A 408
Query: 449 ADCINL----PGSFQCRCRDGWRG 468
A CI + S+ C C G G
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHG 432
Score = 92.7 bits (220), Expect = 3e-18
Identities = 88/286 (30%), Positives = 120/286 (41%), Gaps = 78/286 (27%)
Query: 297 CQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTC 352
C H +C N Y C C G+ G +C ++DECA PC GG C + VGS+ C
Sbjct: 117 CHHGATCRNLADRYECHCPLGYA----GVTCEMEVDECASA--PCLHGGSCLDGVGSFRC 170
Query: 353 TCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
C P G + CQ D+DEC Q G+CH+ +
Sbjct: 171 VCA----PGYGGTR--CQLDLDEC---------------------QSQPCAHGGTCHDLV 203
Query: 412 GSFVCQCPD-GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
F C C GY +G C + + E + C A C+ GSF+C C G+ G+
Sbjct: 204 NGFRCDCAGTGY-----EGTHC-EREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGE- 256
Query: 471 ATCE-DVDECLTN----NGGCHPRATCANTDG---------SFR------CLCDTGYKGD 510
CE D DEC ++ G C R+ A G SFR C C G++G
Sbjct: 257 -LCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
G V++DECA+ P L GHC + P G++C C G+
Sbjct: 316 DCG----------VEVDECASRPCL-NGGHCQDLPNGFQCHCPDGY 350
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 7/68 (10%)
Query: 126 PGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH-NTEGSF 183
P C H G CR+L F C C PG+E V+ C C G CH + +G F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCE---AHVDPCH--SAPCARGRCHTHPDGRF 1116
Query: 184 TCHCRPGY 191
C C PG+
Sbjct: 1117 ECRCPPGF 1124
Score = 39.9 bits (89), Expect = 0.024
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 9/80 (11%)
Query: 432 CTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRA 490
C C C H A C +L +F C C GW +G CE VD C ++ C R
Sbjct: 1054 CRGAPVCAPSPC-LHDGA-CRDLFDAFACACGPGW--EGPRCEAHVDPC--HSAPC-ARG 1106
Query: 491 TC-ANTDGSFRCLCDTGYKG 509
C + DG F C C G+ G
Sbjct: 1107 RCHTHPDGRFECRCPPGFGG 1126
Score = 37.1 bits (82), Expect = 0.17
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 6/61 (9%)
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC-VNTAGSFRCECGH 231
DG C + +F C C PG++ + +D C + A C GRC + G F C C
Sbjct: 1068 DGACRDLFDAFACACGPGWEG---PRCEAHVDPC--HSAPCARGRCHTHPDGRFECRCPP 1122
Query: 232 G 232
G
Sbjct: 1123 G 1123
Score = 37.1 bits (82), Expect = 0.17
Identities = 25/76 (32%), Positives = 31/76 (40%), Gaps = 14/76 (18%)
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPAC------TDDDECELGTCDCHPAA--DCINLPG 456
G+C + +F C C G+ +GP C C G C HP +C PG
Sbjct: 1069 GACRDLFDAFACACGPGW-----EGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPG 1123
Query: 457 SFQCRCR-DGWRGDGA 471
RCR DGW G A
Sbjct: 1124 FGGPRCRWDGWAGGWA 1139
Score = 34.3 bits (75), Expect = 1.2
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 200 CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECSITSGICSNG 258
C CA + L G C + +F C CG G E P C+ +D C S C+ G
Sbjct: 1054 CRGAPVCAPSPCL-HDGACRDLFDAFACACGPGWE-GP---RCEAHVDPCH--SAPCARG 1106
Query: 259 ACENQM-GTYQCVCDEGY 275
C G ++C C G+
Sbjct: 1107 RCHTHPDGRFECRCPPGF 1124
Score = 33.5 bits (73), Expect = 2.0
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 8/69 (11%)
Query: 393 SVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
S D P+ C G+C T F C CP ++ GP C C G C P A C
Sbjct: 807 SEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT-----GPTCAQQLWCP-GQ-PCLPPATC 859
Query: 452 INLPGSFQC 460
+P F C
Sbjct: 860 EEVPDGFVC 868
Score = 33.1 bits (72), Expect = 2.7
Identities = 24/95 (25%), Positives = 35/95 (36%), Gaps = 9/95 (9%)
Query: 240 LSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
L C+ C+ S +GAC + + C C G+ ++H RC
Sbjct: 1052 LGCRGAPVCA-PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCH- 1109
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG 334
+ G + C C G+ G CR D AGG
Sbjct: 1110 --THPDGRFECRCPPGF----GGPRCR-WDGWAGG 1137
>AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 122 bits (294), Expect = 3e-27
Identities = 113/397 (28%), Positives = 167/397 (42%), Gaps = 56/397 (14%)
Query: 145 CFPGYE---KDSKNHTCVDVNECEIVDGVCGDGDCHNTEG----SFTCHCRPGYKADDFS 197
C PG E +S +TC + C G +G F C+C PG++
Sbjct: 47 CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGP--- 103
Query: 198 KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECSITSGICS 256
+ +DIDECA G C N A + C C G ++C+ ++DEC+ ++
Sbjct: 104 RCELDIDECASRPCH-HGATCRNLADRYECHCPLGYA----GVTCEMEVDECA-SAPCLH 157
Query: 257 NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGW 316
G+C + +G+++CVC GY + + H VN + C C
Sbjct: 158 GGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVN---GFRCDCAGTG 214
Query: 317 HLRADGRSC-RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DID 373
+ +G C R++ ECA PC C +GS+ C C G + C+ D D
Sbjct: 215 Y---EGTHCEREVLECASA--PCEHNASCLEGLGSFRCLCWPGY------SGELCEVDED 263
Query: 374 ECADLI----STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQG 429
ECA + S L V P GA S + G F+C CP G+ +G
Sbjct: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFP---GAFSFRHAAG-FLCHCPPGF-----EG 314
Query: 430 PAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTNNGGCH 487
C + DEC + C C +LP FQC C DG+ G TC EDVDECL++ C
Sbjct: 315 ADCGVEVDEC--ASRPCLNGGHCQDLPNGFQCHCPDGYA--GPTCEEDVDECLSD--PCL 368
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLR-TVCCVYSC 523
TC++T + C C + G ++ T C ++C
Sbjct: 369 HGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTC 405
Score = 117 bits (281), Expect = 1e-25
Identities = 119/419 (28%), Positives = 160/419 (38%), Gaps = 56/419 (13%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLG----GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
ME CA P C HG G GF C C PG++ +D++EC C
Sbjct: 66 MEPRGCATQP--CHHGALCVPQGPDPTGFRCYCVPGFQGPRCE---LDIDEC--ASRPCH 118
Query: 173 DG-DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
G C N + CHC GY +++DECA L GG C++ GSFRC C
Sbjct: 119 HGATCRNLADRYECHCPLGYAGVTCE---MEVDECASAPCL-HGGSCLDGVGSFRCVCAP 174
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
G +L D+DEC + G C + + ++C C A + +
Sbjct: 175 GYGGTRCQL---DLDECQ-SQPCAHGGTCHDLVNGFRCDC----AGTGYEGTHCEREVLE 226
Query: 292 XXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTV 347
C+H SC+ GS+ C C G+ G C D DECA + PC GG+C
Sbjct: 227 CASAPCEHNASCLEGLGSFRCLCWPGY----SGELCEVDEDECA--SSPCQHGGRCLQRS 280
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDEC-ADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
P A + + C + VDE P L G G
Sbjct: 281 DPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASR-----PCLNG-GH 334
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDG 465
C + F C CPDGY+ GP C +D DEC C H C + + CRC +
Sbjct: 335 CQDLPNGFQCHCPDGYA-----GPTCEEDVDECLSDPC-LH-GGTCSDTVAGYICRCPET 387
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATC----ANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
W G + + + C + C ATC + S+ C C G G G T V
Sbjct: 388 WGGRDCSVQ-LTGCQGHT--CPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSV 443
Score = 112 bits (269), Expect = 4e-24
Identities = 112/384 (29%), Positives = 168/384 (43%), Gaps = 88/384 (22%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGD 173
+++++ECA+ P C HG CRNL + C C GY TC ++V+EC + G
Sbjct: 106 ELDIDECASRP--CHHGATCRNLADRYECHCPLGY----AGVTCEMEVDECASAPCLHG- 158
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHG 232
G C + GSF C C PGY ++ +D+DEC + GG C + FRC+C G G
Sbjct: 159 GSCLDGVGSFRCVCAPGYGG---TRCQLDLDEC-QSQPCAHGGTCHDLVNGFRCDCAGTG 214
Query: 233 MELAPDRLSC-KDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVK-SHXXXXXX 289
E C +++ EC+ S C N +C +G+++C+C GY+ +
Sbjct: 215 YE----GTHCEREVLECA--SAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASS 268
Query: 290 XXXXXXRC-QHS--------CVNTPGSYH--------CTCREGWHLRADGRSCR-DIDEC 331
RC Q S PG++ C C G+ +G C ++DEC
Sbjct: 269 PCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF----EGADCGVEVDEC 324
Query: 332 AGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDE 389
A +RPC GG C++ + C C DG A PTC +D+DEC
Sbjct: 325 A--SRPCLNGGHCQDLPNGFQCHCPDGY------AGPTCEEDVDECLS------------ 364
Query: 390 LQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
DP + G+C +T+ ++C+CP+ + G C+ C+ TC A
Sbjct: 365 -----DPCL----HGGTCSDTVAGYICRCPETWG-----GRDCSVQLTGCQGHTCPL--A 408
Query: 449 ADCINL----PGSFQCRCRDGWRG 468
A CI + S+ C C G G
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHG 432
Score = 92.7 bits (220), Expect = 3e-18
Identities = 88/286 (30%), Positives = 120/286 (41%), Gaps = 78/286 (27%)
Query: 297 CQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTC 352
C H +C N Y C C G+ G +C ++DECA PC GG C + VGS+ C
Sbjct: 117 CHHGATCRNLADRYECHCPLGYA----GVTCEMEVDECASA--PCLHGGSCLDGVGSFRC 170
Query: 353 TCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
C P G + CQ D+DEC Q G+CH+ +
Sbjct: 171 VCA----PGYGGTR--CQLDLDEC---------------------QSQPCAHGGTCHDLV 203
Query: 412 GSFVCQCPD-GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
F C C GY +G C + + E + C A C+ GSF+C C G+ G+
Sbjct: 204 NGFRCDCAGTGY-----EGTHC-EREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGE- 256
Query: 471 ATCE-DVDECLTN----NGGCHPRATCANTDG---------SFR------CLCDTGYKGD 510
CE D DEC ++ G C R+ A G SFR C C G++G
Sbjct: 257 -LCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
G V++DECA+ P L GHC + P G++C C G+
Sbjct: 316 DCG----------VEVDECASRPCL-NGGHCQDLPNGFQCHCPDGY 350
Score = 62.1 bits (144), Expect = 5e-09
Identities = 45/154 (29%), Positives = 64/154 (41%), Gaps = 14/154 (9%)
Query: 126 PGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH-NTEGSF 183
P C H G CR+L F C C PG+E V+ C C G CH + +G F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCE---AHVDPCH--SAPCARGRCHTHPDGRF 1116
Query: 184 TCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK 243
C C PG+ ++ V EC+ N G C + + C C G LA R C+
Sbjct: 1117 ECRCPPGF-GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG--LAGQR--CQ 1171
Query: 244 DIDECSITSGICSN-GACENQMGTYQCVCDEGYA 276
+ + C N G C G +C+C+ ++
Sbjct: 1172 -VPTLPCEANPCLNGGTCRAAGGVSECICNARFS 1204
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/120 (28%), Positives = 44/120 (36%), Gaps = 13/120 (10%)
Query: 394 VDPQIPELCGAGSCH-NTIGSFVCQCPDGYSVKPEQGPAC---TDDDECELGTCDCHPAA 449
VDP C G CH + G F C+CP G+ GP C EC L C +
Sbjct: 1095 VDPCHSAPCARGRCHTHPDGRFECRCPPGFG-----GPRCRLPVPSKECSLNVT-CLDGS 1148
Query: 450 DCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
C + C C +G G + C N C TC G C+C+ + G
Sbjct: 1149 PCEGGSPAANCSCLEGLAGQRCQVPTLP-CEANP--CLNGGTCRAAGGVSECICNARFSG 1205
Score = 46.8 bits (106), Expect = 2e-04
Identities = 40/157 (25%), Positives = 57/157 (36%), Gaps = 25/157 (15%)
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTC---DCHPAADCINLPGSFQC 460
G+C + +F C C G+ +GP C D C C CH D G F+C
Sbjct: 1069 GACRDLFDAFACACGPGW-----EGPRCEAHVDPCHSAPCARGRCHTHPD-----GRFEC 1118
Query: 461 RCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
RC G+ G + + N C + C + C C G G + T+ C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC- 1177
Query: 521 YSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFT 557
+ + C N G C G EC C+ F+
Sbjct: 1178 ----EANPCLN------GGTCRAAGGVSECICNARFS 1204
Score = 41.5 bits (93), Expect = 0.008
Identities = 36/123 (29%), Positives = 46/123 (37%), Gaps = 17/123 (13%)
Query: 432 CTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRA 490
C C C H A C +L +F C C GW +G CE VD C ++ C R
Sbjct: 1054 CRGAPVCAPSPC-LHDGA-CRDLFDAFACACGPGW--EGPRCEAHVDPC--HSAPC-ARG 1106
Query: 491 TC-ANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYE 549
C + DG F C C G+ G L V EC+ + T + C
Sbjct: 1107 RCHTHPDGRFECRCPPGFGGPRCRLP--------VPSKECSLNVTCLDGSPCEGGSPAAN 1158
Query: 550 CDC 552
C C
Sbjct: 1159 CSC 1161
Score = 40.7 bits (91), Expect = 0.013
Identities = 28/122 (22%), Positives = 43/122 (35%), Gaps = 11/122 (9%)
Query: 240 LSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
L C+ C+ S +GAC + + C C G+ ++H RC
Sbjct: 1052 LGCRGAPVCA-PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCH- 1109
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCR---DIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
+ G + C C G+ G CR EC+ G C + C+C +
Sbjct: 1110 --THPDGRFECRCPPGF----GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLE 1163
Query: 357 GL 358
GL
Sbjct: 1164 GL 1165
Score = 33.5 bits (73), Expect = 2.0
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 8/69 (11%)
Query: 393 SVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
S D P+ C G+C T F C CP ++ GP C C G C P A C
Sbjct: 807 SEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT-----GPTCAQQLWCP-GQ-PCLPPATC 859
Query: 452 INLPGSFQC 460
+P F C
Sbjct: 860 EEVPDGFVC 868
>AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 122 bits (294), Expect = 3e-27
Identities = 113/397 (28%), Positives = 167/397 (42%), Gaps = 56/397 (14%)
Query: 145 CFPGYE---KDSKNHTCVDVNECEIVDGVCGDGDCHNTEG----SFTCHCRPGYKADDFS 197
C PG E +S +TC + C G +G F C+C PG++
Sbjct: 47 CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGP--- 103
Query: 198 KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECSITSGICS 256
+ +DIDECA G C N A + C C G ++C+ ++DEC+ ++
Sbjct: 104 RCELDIDECASRPCH-HGATCRNLADRYECHCPLGYA----GVTCEMEVDECA-SAPCLH 157
Query: 257 NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGW 316
G+C + +G+++CVC GY + + H VN + C C
Sbjct: 158 GGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVN---GFRCDCAGTG 214
Query: 317 HLRADGRSC-RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DID 373
+ +G C R++ ECA PC C +GS+ C C G + C+ D D
Sbjct: 215 Y---EGTHCEREVLECASA--PCEHNASCLEGLGSFRCLCWPGY------SGELCEVDED 263
Query: 374 ECADLI----STIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQG 429
ECA + S L V P GA S + G F+C CP G+ +G
Sbjct: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFP---GAFSFRHAAG-FLCHCPPGF-----EG 314
Query: 430 PAC-TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC-EDVDECLTNNGGCH 487
C + DEC + C C +LP FQC C DG+ G TC EDVDECL++ C
Sbjct: 315 ADCGVEVDEC--ASRPCLNGGHCQDLPNGFQCHCPDGYA--GPTCEEDVDECLSD--PCL 368
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLR-TVCCVYSC 523
TC++T + C C + G ++ T C ++C
Sbjct: 369 HGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTC 405
Score = 117 bits (281), Expect = 1e-25
Identities = 119/419 (28%), Positives = 160/419 (38%), Gaps = 56/419 (13%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLG----GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
ME CA P C HG G GF C C PG++ +D++EC C
Sbjct: 66 MEPRGCATQP--CHHGALCVPQGPDPTGFRCYCVPGFQGPRCE---LDIDEC--ASRPCH 118
Query: 173 DG-DCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
G C N + CHC GY +++DECA L GG C++ GSFRC C
Sbjct: 119 HGATCRNLADRYECHCPLGYAGVTCE---MEVDECASAPCL-HGGSCLDGVGSFRCVCAP 174
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
G +L D+DEC + G C + + ++C C A + +
Sbjct: 175 GYGGTRCQL---DLDECQ-SQPCAHGGTCHDLVNGFRCDC----AGTGYEGTHCEREVLE 226
Query: 292 XXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTV 347
C+H SC+ GS+ C C G+ G C D DECA + PC GG+C
Sbjct: 227 CASAPCEHNASCLEGLGSFRCLCWPGY----SGELCEVDEDECA--SSPCQHGGRCLQRS 280
Query: 348 GSYTCTCTDGLVPSAAGAKPTCQDIDEC-ADLISTIIMMSVDELQKSVDPQIPELCGAGS 406
P A + + C + VDE P L G G
Sbjct: 281 DPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASR-----PCLNG-GH 334
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCRDG 465
C + F C CPDGY+ GP C +D DEC C H C + + CRC +
Sbjct: 335 CQDLPNGFQCHCPDGYA-----GPTCEEDVDECLSDPC-LH-GGTCSDTVAGYICRCPET 387
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATC----ANTDGSFRCLCDTGYKGDGYGLRTVCCV 520
W G + + + C + C ATC + S+ C C G G G T V
Sbjct: 388 WGGRDCSVQ-LTGCQGHT--CPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSV 443
Score = 112 bits (269), Expect = 4e-24
Identities = 112/384 (29%), Positives = 168/384 (43%), Gaps = 88/384 (22%)
Query: 116 QMEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGD 173
+++++ECA+ P C HG CRNL + C C GY TC ++V+EC + G
Sbjct: 106 ELDIDECASRP--CHHGATCRNLADRYECHCPLGY----AGVTCEMEVDECASAPCLHG- 158
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHG 232
G C + GSF C C PGY ++ +D+DEC + GG C + FRC+C G G
Sbjct: 159 GSCLDGVGSFRCVCAPGYGG---TRCQLDLDEC-QSQPCAHGGTCHDLVNGFRCDCAGTG 214
Query: 233 MELAPDRLSC-KDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVK-SHXXXXXX 289
E C +++ EC+ S C N +C +G+++C+C GY+ +
Sbjct: 215 YE----GTHCEREVLECA--SAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASS 268
Query: 290 XXXXXXRC-QHS--------CVNTPGSYH--------CTCREGWHLRADGRSCR-DIDEC 331
RC Q S PG++ C C G+ +G C ++DEC
Sbjct: 269 PCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF----EGADCGVEVDEC 324
Query: 332 AGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTC-QDIDECADLISTIIMMSVDE 389
A +RPC GG C++ + C C DG A PTC +D+DEC
Sbjct: 325 A--SRPCLNGGHCQDLPNGFQCHCPDGY------AGPTCEEDVDECLS------------ 364
Query: 390 LQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPA 448
DP + G+C +T+ ++C+CP+ + G C+ C+ TC A
Sbjct: 365 -----DPCL----HGGTCSDTVAGYICRCPETWG-----GRDCSVQLTGCQGHTCPL--A 408
Query: 449 ADCINL----PGSFQCRCRDGWRG 468
A CI + S+ C C G G
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHG 432
Score = 92.7 bits (220), Expect = 3e-18
Identities = 88/286 (30%), Positives = 120/286 (41%), Gaps = 78/286 (27%)
Query: 297 CQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTC 352
C H +C N Y C C G+ G +C ++DECA PC GG C + VGS+ C
Sbjct: 117 CHHGATCRNLADRYECHCPLGYA----GVTCEMEVDECASA--PCLHGGSCLDGVGSFRC 170
Query: 353 TCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI 411
C P G + CQ D+DEC Q G+CH+ +
Sbjct: 171 VCA----PGYGGTR--CQLDLDEC---------------------QSQPCAHGGTCHDLV 203
Query: 412 GSFVCQCPD-GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
F C C GY +G C + + E + C A C+ GSF+C C G+ G+
Sbjct: 204 NGFRCDCAGTGY-----EGTHC-EREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGE- 256
Query: 471 ATCE-DVDECLTN----NGGCHPRATCANTDG---------SFR------CLCDTGYKGD 510
CE D DEC ++ G C R+ A G SFR C C G++G
Sbjct: 257 -LCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315
Query: 511 GYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
G V++DECA+ P L GHC + P G++C C G+
Sbjct: 316 DCG----------VEVDECASRPCL-NGGHCQDLPNGFQCHCPDGY 350
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 7/68 (10%)
Query: 126 PGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH-NTEGSF 183
P C H G CR+L F C C PG+E V+ C C G CH + +G F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCE---AHVDPCH--SAPCARGRCHTHPDGRF 1116
Query: 184 TCHCRPGY 191
C C PG+
Sbjct: 1117 ECRCPPGF 1124
Score = 39.9 bits (89), Expect = 0.024
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 9/80 (11%)
Query: 432 CTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRA 490
C C C H A C +L +F C C GW +G CE VD C ++ C R
Sbjct: 1054 CRGAPVCAPSPC-LHDGA-CRDLFDAFACACGPGW--EGPRCEAHVDPC--HSAPC-ARG 1106
Query: 491 TC-ANTDGSFRCLCDTGYKG 509
C + DG F C C G+ G
Sbjct: 1107 RCHTHPDGRFECRCPPGFGG 1126
Score = 37.1 bits (82), Expect = 0.17
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 6/61 (9%)
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC-VNTAGSFRCECGH 231
DG C + +F C C PG++ + +D C + A C GRC + G F C C
Sbjct: 1068 DGACRDLFDAFACACGPGWEG---PRCEAHVDPC--HSAPCARGRCHTHPDGRFECRCPP 1122
Query: 232 G 232
G
Sbjct: 1123 G 1123
Score = 37.1 bits (82), Expect = 0.17
Identities = 25/76 (32%), Positives = 31/76 (40%), Gaps = 14/76 (18%)
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPAC------TDDDECELGTCDCHPAA--DCINLPG 456
G+C + +F C C G+ +GP C C G C HP +C PG
Sbjct: 1069 GACRDLFDAFACACGPGW-----EGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPG 1123
Query: 457 SFQCRCR-DGWRGDGA 471
RCR DGW G A
Sbjct: 1124 FGGPRCRWDGWAGGWA 1139
Score = 34.3 bits (75), Expect = 1.2
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 200 CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCK-DIDECSITSGICSNG 258
C CA + L G C + +F C CG G E P C+ +D C S C+ G
Sbjct: 1054 CRGAPVCAPSPCL-HDGACRDLFDAFACACGPGWE-GP---RCEAHVDPCH--SAPCARG 1106
Query: 259 ACENQM-GTYQCVCDEGY 275
C G ++C C G+
Sbjct: 1107 RCHTHPDGRFECRCPPGF 1124
Score = 33.5 bits (73), Expect = 2.0
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 8/69 (11%)
Query: 393 SVDPQIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADC 451
S D P+ C G+C T F C CP ++ GP C C G C P A C
Sbjct: 807 SEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT-----GPTCAQQLWCP-GQ-PCLPPATC 859
Query: 452 INLPGSFQC 460
+P F C
Sbjct: 860 EEVPDGFVC 868
Score = 33.1 bits (72), Expect = 2.7
Identities = 24/95 (25%), Positives = 35/95 (36%), Gaps = 9/95 (9%)
Query: 240 LSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
L C+ C+ S +GAC + + C C G+ ++H RC
Sbjct: 1052 LGCRGAPVCA-PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCH- 1109
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGG 334
+ G + C C G+ G CR D AGG
Sbjct: 1110 --THPDGRFECRCPPGF----GGPRCR-WDGWAGG 1137
>AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens
cDNA FLJ16811 fis, clone THYMU3024602, highly similar
to Cell surface glycoprotein EMR1 precursor. ).
Length = 867
Score = 120 bits (288), Expect = 2e-26
Identities = 71/241 (29%), Positives = 100/241 (41%), Gaps = 29/241 (12%)
Query: 147 PGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKAD-------DFSKI 199
P + ++K + C D C C NT S+ C C+ G+ + D
Sbjct: 24 PTRKPNTKGNNCRDSTLCPAY------ATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR 77
Query: 200 CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C DI+EC + CVN+ GS+ C C G +C+D+DEC+ +
Sbjct: 78 CKDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF--ISRNSTCEDVDECADPRACPEHAT 135
Query: 260 CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH------SCVNTPGSYHCTCR 313
C N +G Y C C+ G+ S+ C +C NTPGSY CTC
Sbjct: 136 CNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCH 195
Query: 314 EGW-------HLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGA 365
G+ + G CRDIDEC CG C N +GSY+C C G P+ G+
Sbjct: 196 PGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGS 255
Query: 366 K 366
+
Sbjct: 256 Q 256
Score = 119 bits (286), Expect = 3e-26
Identities = 64/164 (39%), Positives = 84/164 (51%), Gaps = 13/164 (7%)
Query: 401 LCGA-GSCHNTIGSFVCQCPDGYSVKPEQ------GPACTDDDECELGTCDCHPAADCIN 453
LC A +C NT+ S+ C C G+ Q G C D +EC L + C +DC+N
Sbjct: 40 LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINEC-LTSSVCPEHSDCVN 98
Query: 454 LPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYG 513
GS+ C C+ G+ +TCEDVDEC + C ATC NT G++ C C+ G++
Sbjct: 99 SMGSYSCSCQVGFISRNSTCEDVDEC-ADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 157
Query: 514 LRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGF 556
L SC DIDEC +C N C+NTPG Y C C GF
Sbjct: 158 LSFQGLKASCEDIDECTE---MCPINSTCTNTPGSYFCTCHPGF 198
Score = 115 bits (276), Expect = 5e-25
Identities = 76/258 (29%), Positives = 110/258 (42%), Gaps = 51/258 (19%)
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGW-------HLRADGRSC 325
EG+ + T K + +C NT SY+C C++G+ H + G C
Sbjct: 19 EGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRC 78
Query: 326 RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMM 385
+DI+EC + C N++GSY+C+C G + TC+D+DECAD
Sbjct: 79 KDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFI----SRNSTCEDVDECAD-------- 126
Query: 386 SVDELQKSVDPQIPELCGA-GSCHNTIGSFVCQCPDGYSVKPE----QG--PACTDDDEC 438
P C +C+NT+G++ C C G+ QG +C D DEC
Sbjct: 127 -------------PRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC 173
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDG---------WRGDGATCEDVDECLTNNGGCHPR 489
T C + C N PGS+ C C G + G C D+DEC + C P
Sbjct: 174 ---TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPN 230
Query: 490 ATCANTDGSFRCLCDTGY 507
+ C N GS+ C C G+
Sbjct: 231 SICTNALGSYSCGCIAGF 248
Score = 113 bits (272), Expect = 2e-24
Identities = 70/220 (31%), Positives = 100/220 (45%), Gaps = 30/220 (13%)
Query: 128 LC-GHGRCRNLLGGFTCDCFPGY-EKDSKNH------TCVDVNECEIVDGVCGD-GDCHN 178
LC + C N + + C C G+ + +NH C D+NEC + VC + DC N
Sbjct: 40 LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINEC-LTSSVCPEHSDCVN 98
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
+ GS++C C+ G+ + + + C D+DECAD A C NT G++ C C G E +
Sbjct: 99 SMGSYSCSCQVGFISRNST--CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSG 156
Query: 239 RL-------SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
L SC+DIDEC+ I N C N G+Y C C G+A S + +
Sbjct: 157 HLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVEC 214
Query: 292 XXXXRCQHS---------CVNTPGSYHCTCREGWHLRADG 322
C+ C N GSY C C G+H +G
Sbjct: 215 RDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 254
Score = 113 bits (271), Expect = 2e-24
Identities = 84/256 (32%), Positives = 107/256 (41%), Gaps = 48/256 (18%)
Query: 322 GRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAG---AKP--TCQDIDECA 376
G +CRD C A C NTV SY C C G + S P C+DI+EC
Sbjct: 32 GNNCRDSTLCPAYAT------CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINEC- 84
Query: 377 DLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDD 436
L SV P+ + C N++GS+ C C G+ + C D D
Sbjct: 85 -------------LTSSVCPEHSD------CVNSMGSYSCSCQVGFI---SRNSTCEDVD 122
Query: 437 ECELGTCDCHPAADCINLPGSFQCRCRDGW---------RGDGATCEDVDECLTNNGGCH 487
EC C A C N G++ C C G+ +G A+CED+DEC C
Sbjct: 123 ECADPRA-CPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEM---CP 178
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPG 546
+TC NT GS+ C C G+ L C DIDEC DP+ C N C+N G
Sbjct: 179 INSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALG 238
Query: 547 GYECDCDVGFTRAADG 562
Y C C GF +G
Sbjct: 239 SYSCGCIAGFHPNPEG 254
Score = 106 bits (254), Expect = 2e-22
Identities = 80/242 (33%), Positives = 102/242 (42%), Gaps = 39/242 (16%)
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGM-------ELAPDRLSCKDIDECSITSGIC- 255
+ C D+ C NT S+ C C G + CKDI+EC +TS +C
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINEC-LTSSVCP 91
Query: 256 SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC-QHS-CVNTPGSYHCTCR 313
+ C N MG+Y C C G+ ++ C +H+ C NT G+Y C C
Sbjct: 92 EHSDCVNSMGSYSCSCQVGFIS---RNSTCEDVDECADPRACPEHATCNNTVGNYSCFCN 148
Query: 314 EGW-----HLRADG--RSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAK 366
G+ HL G SC DIDEC P C NT GSY CTC G PS
Sbjct: 149 PGFESSSGHLSFQGLKASCEDIDECTEMC-PINS-TCTNTPGSYFCTCHPGFAPSNGQLN 206
Query: 367 PTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGYSVK 425
T Q + EC D +DE + Q P CG S C N +GS+ C C G+
Sbjct: 207 FTDQGV-ECRD---------IDECR-----QDPSTCGPNSICTNALGSYSCGCIAGFHPN 251
Query: 426 PE 427
PE
Sbjct: 252 PE 253
Score = 104 bits (249), Expect = 1e-21
Identities = 55/173 (31%), Positives = 79/173 (45%), Gaps = 19/173 (10%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++NEC H C N +G ++C C G+ S+N TC DV+EC C+
Sbjct: 80 DINECLTSSVCPEHSDCVNSMGSYSCSCQVGF--ISRNSTCEDVDECADPRACPEHATCN 137
Query: 178 NTEGSFTCHCRPGYKADD-------FSKICVDIDECADNDALCRGGRCVNTAGSFRCECG 230
NT G+++C C PG+++ C DIDEC + + C NT GS+ C C
Sbjct: 138 NTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCH 195
Query: 231 HG-------MELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGY 275
G + + C+DIDEC C N C N +G+Y C C G+
Sbjct: 196 PGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 248
Score = 80.2 bits (189), Expect = 2e-14
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 23/154 (14%)
Query: 424 VKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW---------RGDGATCE 474
++P + P T + C T C A C N S+ C C+ G+ + G C+
Sbjct: 22 IRPTRKPN-TKGNNCRDSTL-CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCK 79
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D++ECLT++ C + C N+ GS+ C C G+ + +C D+DECA DP
Sbjct: 80 DINECLTSSV-CPEHSDCVNSMGSYSCSCQVGF---------ISRNSTCEDVDECA-DPR 128
Query: 535 LC-ENGHCSNTPGGYECDCDVGFTRAADGRSCLG 567
C E+ C+NT G Y C C+ GF ++ S G
Sbjct: 129 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQG 162
Score = 74.9 bits (176), Expect = 7e-13
Identities = 45/137 (32%), Positives = 64/137 (46%), Gaps = 19/137 (13%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKN-------HTCVDVNECEIVDG 169
+V+ECA P C H C N +G ++C C PG+E S + +C D++EC +
Sbjct: 120 DVDECAD-PRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCP 178
Query: 170 VCGDGDCHNTEGSFTCHCRPGYKAD-------DFSKICVDIDECADNDALC-RGGRCVNT 221
+ + C NT GS+ C C PG+ D C DIDEC + + C C N
Sbjct: 179 I--NSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNA 236
Query: 222 AGSFRCECGHGMELAPD 238
GS+ C C G P+
Sbjct: 237 LGSYSCGCIAGFHPNPE 253
>D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein.
Length = 2589
Score = 119 bits (287), Expect = 2e-26
Identities = 106/373 (28%), Positives = 147/373 (39%), Gaps = 50/373 (13%)
Query: 199 ICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG 258
+ V C + A +CVN FRC G ++ P R SC S + G CS
Sbjct: 1272 LTVGSSRCLHSHAEALREKCVNCTRRFRCTQGFQLQDTP-RKSCVYRSGFSFSRG-CSY- 1328
Query: 259 ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHL 318
C ++ C C G+ + + +CQ + GS C C EG+H
Sbjct: 1329 TCAKKIQVPDC-CP-GFFGTLCEPCPGGLGGVCSGHGQCQDRFL---GSGECHCHEGFH- 1382
Query: 319 RADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
G +C + C G G C C C GL +C
Sbjct: 1383 ---GTAC---EVCELGRY---GPNCTGV-----CDCAHGLCQEGLQGDGSC--------- 1419
Query: 379 ISTIIMMSVDELQKSVDPQIPELC--GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDD 436
+ + + QK PQ P C A ++ G+ C C GYS G C++ D
Sbjct: 1420 VCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYS---GNGIFCSEVD 1476
Query: 437 ECELGTCDCHPAADCINL-PGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANT 495
C G C P A+C + PG C C+DG+ GDG C++++ CL ++GGCH A C T
Sbjct: 1477 PCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPT 1536
Query: 496 -DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYE-CDC 552
C C GY GD G+RT C +D C+ + C C +T G C C
Sbjct: 1537 GPQQVSCSCREGYSGD--GIRT------CELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1588
Query: 553 DVGFTRAADGRSC 565
D T DG +C
Sbjct: 1589 DTAHT-VGDGLTC 1600
Score = 89.8 bits (213), Expect = 2e-17
Identities = 71/224 (31%), Positives = 88/224 (39%), Gaps = 26/224 (11%)
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ-IPELCGAGS-CHN 409
C C GL + G+ CQ CA S +E P + + C + C +
Sbjct: 803 CGCVHGLCDNRPGSGGVCQQ-GTCAPGFSGRFC---NESMGDCGPTGLAQHCHLHARCVS 858
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECEL-GTCDCHPAADCI-NLPGSFQCRCRDGWR 467
G C+C DG+ G +CT + C C A+C+ G+ C C GW
Sbjct: 859 QEGVARCRCLDGFE---GDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWS 915
Query: 468 GDGATCEDVDEC-LTNNGGCHPRATCANTD-GSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
GDG C +DEC L GGCH A C+ G RC C G+ GDGY C
Sbjct: 916 GDGRVCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGY---------QCSP 966
Query: 526 IDECANDPTLCEN-GHCSNTPGGYE-CDCDVGFTRAADGRSCLG 567
ID C C C GG C C GF DG SC G
Sbjct: 967 IDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF--GGDGFSCYG 1008
Score = 80.6 bits (190), Expect = 1e-14
Identities = 80/259 (30%), Positives = 101/259 (38%), Gaps = 26/259 (10%)
Query: 118 EVNEC-AAFPGLC-GHGRCRN-LLGGFTCDCFPGYEKDSKNHTCVDVN----ECEIVDGV 170
+ +C F C G G C + + G C CFP Y K H C + N +C+ D
Sbjct: 747 DCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDY-KGIACHICSNPNKHGEQCQ-EDCG 804
Query: 171 CGDGDCHNTEGSFTCHCRPGYKADDFS-KICVD-IDECADNDAL--CR-GGRCVNTAGSF 225
C G C N GS C+ G A FS + C + + +C C RCV+ G
Sbjct: 805 CVHGLCDNRPGSGGV-CQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVA 863
Query: 226 RCECGHGMELAPDRLSCKDIDECSITS-GICS-NGAC-ENQMGTYQCVCDEGYA-QSTVK 281
RC C G E D SC + CS G CS N C +GT+ C C +G++ V
Sbjct: 864 RCRCLDGFE--GDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVC 921
Query: 282 SHXXXXXXXXXXXXRCQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG 340
C PG CTC+ G+ DG C ID C G C G
Sbjct: 922 VAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGF--AGDGYQCSPIDPCRAGNGGCHG 979
Query: 341 -GQCRNTVGSY-TCTCTDG 357
CR G CTC G
Sbjct: 980 LATCRAVGGGQRVCTCPPG 998
Score = 79.8 bits (188), Expect = 2e-14
Identities = 66/183 (36%), Positives = 81/183 (44%), Gaps = 30/183 (16%)
Query: 397 QIPELCGA--GSCHNTIGSF-VCQ---CPDGYSVKPEQGPACTDD-DEC-ELGTCD-CHP 447
Q E CG G C N GS VCQ C G+S G C + +C G CH
Sbjct: 798 QCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS-----GRFCNESMGDCGPTGLAQHCHL 852
Query: 448 AADCINLPGSFQCRCRDGWRGDGATCEDVDECL-TNNGGCHPRATCA-NTDGSFRCLCDT 505
A C++ G +CRC DG+ GDG +C + C + GGC A C + G+ C C
Sbjct: 853 HARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHK 912
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPT-LCE-NGHCSNT-PGGYECDCDVGFTRAADG 562
G+ GDG CV IDEC D C + CS PG C C +GF A DG
Sbjct: 913 GWSGDG---------RVCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGF--AGDG 961
Query: 563 RSC 565
C
Sbjct: 962 YQC 964
Score = 67.3 bits (157), Expect = 1e-10
Identities = 49/165 (29%), Positives = 66/165 (40%), Gaps = 20/165 (12%)
Query: 405 GSCHNTIG-SFVCQCPDGYSVKPEQGPACTDDDECE-LGTCDCHPAADCINLPGSFQCRC 462
G C +G S C C +G++ GP C E + + T C P A C C C
Sbjct: 2046 GRCDEGLGGSGSCFCDEGWT-----GPRCEVQLELQPVCTPPCAPEAVC---RAGNSCEC 2097
Query: 463 RDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ GDG C D C +GGC A C+ C C Y+GDG+ R
Sbjct: 2098 SLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCR---ARNP 2154
Query: 523 CVDIDECANDPTLCENGHCSNTP-GGYECDCDVGFTRAADGRSCL 566
C D + E+ +C +T C+C G+ DG CL
Sbjct: 2155 CTD----GHRGGCSEHANCLSTGLNTRRCECHAGY--VGDGLQCL 2193
Score = 62.9 bits (146), Expect = 3e-09
Identities = 45/151 (29%), Positives = 61/151 (40%), Gaps = 10/151 (6%)
Query: 131 HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVD-GVCGDG-DC-HNTEGSFTCHC 187
H RC + G C C G+E D +C N C D G C + +C + G+ C C
Sbjct: 853 HARCVSQEGVARCRCLDGFEGDG--FSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTC 910
Query: 188 RPGYKADDFSKICVDIDECA-DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
G+ D ++CV IDEC D C + G + C + A D C ID
Sbjct: 911 HKGWSGD--GRVCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPID 968
Query: 247 ECSITSGICSNGACENQMGTYQ--CVCDEGY 275
C +G C A +G Q C C G+
Sbjct: 969 PCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 999
Score = 61.7 bits (143), Expect = 7e-09
Identities = 71/263 (26%), Positives = 95/263 (36%), Gaps = 41/263 (15%)
Query: 330 ECAGGAR-PCGG-GQCRNTVG-SYTCTCTDGLVPSAAGA-------KPTCQDIDECADLI 379
EC GGA PC G G C + + + TC C + SA P CQ + C +
Sbjct: 130 ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGV 189
Query: 380 ST-------IIMMSVDELQKSVDPQIPELCGAGSC-HNTIGSFV---CQCPDGYSVKPEQ 428
+ D ++P +C C NT S C+C GY+ +Q
Sbjct: 190 CNHGPRGDGSCLCFAGYTGPHCDQELP-VCQELRCPQNTQCSAEAPSCRCLPGYT---QQ 245
Query: 429 GPACTDDDECELGTCDCHPAADCINLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCH 487
G C + C C A C P G QC C + + GDG C D C N GGC
Sbjct: 246 GSECRAPNPCWPSPCSL--LAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCP 303
Query: 488 PRAT-CA-NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNT 544
+T C G C C G C + C+ P C+ + C T
Sbjct: 304 SNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAF-------CS--PFSCDRSATCQVT 354
Query: 545 PGGYECDCDVGFTRAADGRSCLG 567
G + C + DGR+C G
Sbjct: 355 ADG-KTSCVCRESEVGDGRACYG 376
Score = 60.5 bits (140), Expect = 2e-08
Identities = 63/217 (29%), Positives = 84/217 (38%), Gaps = 20/217 (9%)
Query: 172 GDGDCHN-TEGSFTCHCRPGYKADDFSKICVDID---ECADNDALCRGGRCVNTAGSFR- 226
G G+C + +G+ C C P YK IC + + E D C G C N GS
Sbjct: 761 GKGNCSDGIQGNGACLCFPDYKGIA-CHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGV 819
Query: 227 CECGHGMELAPDRLSCKDIDECSITSGICSN----GACENQMGTYQCVCDEGYAQSTVKS 282
C+ G R + + +C T G+ + C +Q G +C C +G+ + S
Sbjct: 820 CQQGTCAPGFSGRFCNESMGDCGPT-GLAQHCHLHARCVSQEGVARCRCLDGF-EGDGFS 877
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGS---YHCTCREGWHLRADGRSCRDIDECAGGAR-PC 338
C + PGS +HCTC +GW DGR C IDEC R C
Sbjct: 878 CTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGW--SGDGRVCVAIDECELDVRGGC 935
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
+ VG CT L AG C ID C
Sbjct: 936 HTDALCSYVGPGQSRCTCKL--GFAGDGYQCSPIDPC 970
Score = 54.8 bits (126), Expect = 8e-07
Identities = 42/143 (29%), Positives = 57/143 (39%), Gaps = 11/143 (7%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDCHNTE-GSFTCHCRPGYKADDF 196
G TC C GY C +V+ C G C +C G TC C+ GY D
Sbjct: 1455 GASTCACAAGYS--GNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGD-- 1510
Query: 197 SKICVDIDECADNDALCR-GGRCVNTAGS-FRCECGHGMELAPDRLSCKDIDECSITSGI 254
++C +I+ C + C C+ T C C G R +C+ +D CS +G
Sbjct: 1511 GELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIR-TCELLDPCSKNNGG 1569
Query: 255 CSNGACENQMGTYQ--CVCDEGY 275
CS A G Q C CD +
Sbjct: 1570 CSPYATCKSTGDGQRTCTCDTAH 1592
Score = 51.6 bits (118), Expect = 7e-06
Identities = 59/227 (25%), Positives = 87/227 (38%), Gaps = 38/227 (16%)
Query: 169 GVC-GDGDCHNTE-GSFTCHCRPGY--------KADDFSKICVDIDECADNDALCRGGRC 218
GVC G G C + GS CHC G+ + + C + +CA LC+ G
Sbjct: 1357 GVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHG--LCQEG-- 1412
Query: 219 VNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICS-----NGAC-ENQMGTYQCVCD 272
G C C G + L C ITS C N C ++ G C C
Sbjct: 1413 --LQGDGSCVCNVGWQ----GLRCDQ----KITSPQCPRKCDPNANCVQDSAGASTCACA 1462
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDEC 331
GY+ + + +C PG CTC++G+ DG C++I+ C
Sbjct: 1463 AGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGY--MGDGELCQEINSC 1520
Query: 332 AGGARPCG-GGQCRNT-VGSYTCTCTDGLVPSAAGAKPTCQDIDECA 376
C +C T +C+C +G S G + TC+ +D C+
Sbjct: 1521 LIHHGGCHIHAECIPTGPQQVSCSCREGY--SGDGIR-TCELLDPCS 1564
Score = 48.0 bits (109), Expect = 9e-05
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 10/112 (8%)
Query: 140 GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDCHNTEGSFTCHCRPGYKADDFSK 198
G +C+C GYE D + T D+ C+ G C + +C TC C P Y+ D +S
Sbjct: 2092 GNSCECSLGYEGDGRVCTVADL--CQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWS- 2148
Query: 199 ICVDIDECAD--NDALCRGGRCVNTA-GSFRCECGHGMELAPDRLSCKDIDE 247
C + C D C++T + RCEC G D L C + E
Sbjct: 2149 -CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAG--YVGDGLQCLEESE 2197
Score = 39.9 bits (89), Expect = 0.024
Identities = 60/235 (25%), Positives = 74/235 (31%), Gaps = 27/235 (11%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVD-GVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C PGY S+ H C E G C DG N TC C+ ++ C
Sbjct: 119 CCPGYW-GSRCHECPGGAETPCNGHGTCLDGMDRNG----TCVCQENFRGS----AC--- 166
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID--ECSITSGICSNGAC- 260
EC D + G C + C HG L C +C C
Sbjct: 167 QECQDPNRF--GPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCP 224
Query: 261 ENQMGTYQ---CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWH 317
+N + + C C GY Q + Q S V+ G C C E +H
Sbjct: 225 QNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCS-VSPKGQAQCHCPENYH 283
Query: 318 LRADGRSCRDIDECAG--GARPCGGGQC-RNTVGSYTCTCTDGLVPSAAGAKPTC 369
DG C D C G P C G CTC GLV + A C
Sbjct: 284 --GDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGC 336
Score = 38.7 bits (86), Expect = 0.054
Identities = 59/219 (26%), Positives = 83/219 (37%), Gaps = 40/219 (18%)
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTV---------GSYTCTCTD 356
GS C CR G+ G +C + CA GA CR TV GS +C C +
Sbjct: 2010 GSGQCLCRSGFA----GTAC---ELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDE 2062
Query: 357 GLVPSAAGAKPTCQDI--DECADLISTIIMMSVD-ELQKSVDPQI---PELC--GAGSCH 408
G + Q + CA S + L D ++ +LC G G C
Sbjct: 2063 GWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCS 2122
Query: 409 -----NTIGSFV-CQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLP-GSFQC 460
+ +G+ V C C Y G +C + C G C A+C++ + +C
Sbjct: 2123 EHANCSQVGTMVTCTCLPDYE---GDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC 2179
Query: 461 RCRDGWRGDGATCED-----VDECLTNNGGCHPRATCAN 494
C G+ GDG C + VD CL CH A C +
Sbjct: 2180 ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTD 2218
Score = 35.1 bits (77), Expect = 0.67
Identities = 50/197 (25%), Positives = 68/197 (34%), Gaps = 24/197 (12%)
Query: 130 GHGRCRNLLG-GFTCDCFPGYEKDSKNHTCVDVN----ECEIVDGVCGDGDC-HNTEGSF 183
GHG C + + TC C + + S C D N +C+ V C G C H G
Sbjct: 141 GHGTCLDGMDRNGTCVCQENF-RGSACQECQDPNRFGPDCQSVCS-CVHGVCNHGPRGDG 198
Query: 184 TCHCRPGYKA---DDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
+C C GY D +C ++ C N +C A S RC G+ + +
Sbjct: 199 SCLCFAGYTGPHCDQELPVCQEL-RCPQNT------QCSAEAPSCRCLPGYTQQGS---- 247
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXXRCQH 299
C+ + C + + G QC C E Y V
Sbjct: 248 ECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNST 307
Query: 300 SCV-NTPGSYHCTCREG 315
CV PG CTCR G
Sbjct: 308 LCVYQKPGQAFCTCRPG 324
Score = 32.3 bits (70), Expect = 4.7
Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 5/71 (7%)
Query: 127 GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC-EIVDGVCGD-GDCHNTE-GSF 183
G H C + TC C P YE D +C N C + G C + +C +T +
Sbjct: 2120 GCSEHANCSQVGTMVTCTCLPDYEGD--GWSCRARNPCTDGHRGGCSEHANCLSTGLNTR 2177
Query: 184 TCHCRPGYKAD 194
C C GY D
Sbjct: 2178 RCECHAGYVGD 2188
Score = 31.9 bits (69), Expect = 6.2
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 4/61 (6%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSF-TCHCRPGYKADDF 196
G C C G+ D + C ++ C +G C G C G C C PG+ D F
Sbjct: 947 GQSRCTCKLGFAGDG--YQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGF 1004
Query: 197 S 197
S
Sbjct: 1005 S 1005
>DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein.
Length = 2570
Score = 119 bits (287), Expect = 2e-26
Identities = 106/373 (28%), Positives = 147/373 (39%), Gaps = 50/373 (13%)
Query: 199 ICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG 258
+ V C + A +CVN FRC G ++ P R SC S + G CS
Sbjct: 1253 LTVGSSRCLHSHAEALREKCVNCTRRFRCTQGFQLQDTP-RKSCVYRSGFSFSRG-CSY- 1309
Query: 259 ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHL 318
C ++ C C G+ + + +CQ + GS C C EG+H
Sbjct: 1310 TCAKKIQVPDC-CP-GFFGTLCEPCPGGLGGVCSGHGQCQDRFL---GSGECHCHEGFH- 1363
Query: 319 RADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
G +C + C G G C C C GL +C
Sbjct: 1364 ---GTAC---EVCELGRY---GPNCTGV-----CDCAHGLCQEGLQGDGSC--------- 1400
Query: 379 ISTIIMMSVDELQKSVDPQIPELC--GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDD 436
+ + + QK PQ P C A ++ G+ C C GYS G C++ D
Sbjct: 1401 VCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYS---GNGIFCSEVD 1457
Query: 437 ECELGTCDCHPAADCINL-PGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANT 495
C G C P A+C + PG C C+DG+ GDG C++++ CL ++GGCH A C T
Sbjct: 1458 PCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPT 1517
Query: 496 -DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYE-CDC 552
C C GY GD G+RT C +D C+ + C C +T G C C
Sbjct: 1518 GPQQVSCSCREGYSGD--GIRT------CELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
Query: 553 DVGFTRAADGRSC 565
D T DG +C
Sbjct: 1570 DTAHT-VGDGLTC 1581
Score = 89.8 bits (213), Expect = 2e-17
Identities = 71/224 (31%), Positives = 88/224 (39%), Gaps = 26/224 (11%)
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ-IPELCGAGS-CHN 409
C C GL + G+ CQ CA S +E P + + C + C +
Sbjct: 784 CGCVHGLCDNRPGSGGVCQQ-GTCAPGFSGRFC---NESMGDCGPTGLAQHCHLHARCVS 839
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECEL-GTCDCHPAADCI-NLPGSFQCRCRDGWR 467
G C+C DG+ G +CT + C C A+C+ G+ C C GW
Sbjct: 840 QEGVARCRCLDGFE---GDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWS 896
Query: 468 GDGATCEDVDEC-LTNNGGCHPRATCANTD-GSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
GDG C +DEC L GGCH A C+ G RC C G+ GDGY C
Sbjct: 897 GDGRVCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGY---------QCSP 947
Query: 526 IDECANDPTLCEN-GHCSNTPGGYE-CDCDVGFTRAADGRSCLG 567
ID C C C GG C C GF DG SC G
Sbjct: 948 IDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF--GGDGFSCYG 989
Score = 80.6 bits (190), Expect = 1e-14
Identities = 80/259 (30%), Positives = 101/259 (38%), Gaps = 26/259 (10%)
Query: 118 EVNEC-AAFPGLC-GHGRCRN-LLGGFTCDCFPGYEKDSKNHTCVDVN----ECEIVDGV 170
+ +C F C G G C + + G C CFP Y K H C + N +C+ D
Sbjct: 728 DCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDY-KGIACHICSNPNKHGEQCQ-EDCG 785
Query: 171 CGDGDCHNTEGSFTCHCRPGYKADDFS-KICVD-IDECADNDAL--CR-GGRCVNTAGSF 225
C G C N GS C+ G A FS + C + + +C C RCV+ G
Sbjct: 786 CVHGLCDNRPGSGGV-CQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVA 844
Query: 226 RCECGHGMELAPDRLSCKDIDECSITS-GICS-NGAC-ENQMGTYQCVCDEGYA-QSTVK 281
RC C G E D SC + CS G CS N C +GT+ C C +G++ V
Sbjct: 845 RCRCLDGFE--GDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVC 902
Query: 282 SHXXXXXXXXXXXXRCQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG 340
C PG CTC+ G+ DG C ID C G C G
Sbjct: 903 VAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGF--AGDGYQCSPIDPCRAGNGGCHG 960
Query: 341 -GQCRNTVGSY-TCTCTDG 357
CR G CTC G
Sbjct: 961 LATCRAVGGGQRVCTCPPG 979
Score = 79.8 bits (188), Expect = 2e-14
Identities = 66/183 (36%), Positives = 81/183 (44%), Gaps = 30/183 (16%)
Query: 397 QIPELCGA--GSCHNTIGSF-VCQ---CPDGYSVKPEQGPACTDD-DEC-ELGTCD-CHP 447
Q E CG G C N GS VCQ C G+S G C + +C G CH
Sbjct: 779 QCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS-----GRFCNESMGDCGPTGLAQHCHL 833
Query: 448 AADCINLPGSFQCRCRDGWRGDGATCEDVDECL-TNNGGCHPRATCA-NTDGSFRCLCDT 505
A C++ G +CRC DG+ GDG +C + C + GGC A C + G+ C C
Sbjct: 834 HARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHK 893
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPT-LCE-NGHCSNT-PGGYECDCDVGFTRAADG 562
G+ GDG CV IDEC D C + CS PG C C +GF A DG
Sbjct: 894 GWSGDG---------RVCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGF--AGDG 942
Query: 563 RSC 565
C
Sbjct: 943 YQC 945
Score = 67.3 bits (157), Expect = 1e-10
Identities = 49/165 (29%), Positives = 66/165 (40%), Gaps = 20/165 (12%)
Query: 405 GSCHNTIG-SFVCQCPDGYSVKPEQGPACTDDDECE-LGTCDCHPAADCINLPGSFQCRC 462
G C +G S C C +G++ GP C E + + T C P A C C C
Sbjct: 2027 GRCDEGLGGSGSCFCDEGWT-----GPRCEVQLELQPVCTPPCAPEAVC---RAGNSCEC 2078
Query: 463 RDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ GDG C D C +GGC A C+ C C Y+GDG+ R
Sbjct: 2079 SLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCR---ARNP 2135
Query: 523 CVDIDECANDPTLCENGHCSNTP-GGYECDCDVGFTRAADGRSCL 566
C D + E+ +C +T C+C G+ DG CL
Sbjct: 2136 CTD----GHRGGCSEHANCLSTGLNTRRCECHAGY--VGDGLQCL 2174
Score = 62.9 bits (146), Expect = 3e-09
Identities = 45/151 (29%), Positives = 61/151 (40%), Gaps = 10/151 (6%)
Query: 131 HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVD-GVCGDG-DC-HNTEGSFTCHC 187
H RC + G C C G+E D +C N C D G C + +C + G+ C C
Sbjct: 834 HARCVSQEGVARCRCLDGFEGDG--FSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTC 891
Query: 188 RPGYKADDFSKICVDIDECA-DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
G+ D ++CV IDEC D C + G + C + A D C ID
Sbjct: 892 HKGWSGD--GRVCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPID 949
Query: 247 ECSITSGICSNGACENQMGTYQ--CVCDEGY 275
C +G C A +G Q C C G+
Sbjct: 950 PCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
Score = 61.7 bits (143), Expect = 7e-09
Identities = 71/263 (26%), Positives = 95/263 (36%), Gaps = 41/263 (15%)
Query: 330 ECAGGAR-PCGG-GQCRNTVG-SYTCTCTDGLVPSAAGA-------KPTCQDIDECADLI 379
EC GGA PC G G C + + + TC C + SA P CQ + C +
Sbjct: 111 ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGV 170
Query: 380 ST-------IIMMSVDELQKSVDPQIPELCGAGSC-HNTIGSFV---CQCPDGYSVKPEQ 428
+ D ++P +C C NT S C+C GY+ +Q
Sbjct: 171 CNHGPRGDGSCLCFAGYTGPHCDQELP-VCQELRCPQNTQCSAEAPSCRCLPGYT---QQ 226
Query: 429 GPACTDDDECELGTCDCHPAADCINLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCH 487
G C + C C A C P G QC C + + GDG C D C N GGC
Sbjct: 227 GSECRAPNPCWPSPCSL--LAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCP 284
Query: 488 PRAT-CA-NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNT 544
+T C G C C G C + C+ P C+ + C T
Sbjct: 285 SNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAF-------CS--PFSCDRSATCQVT 335
Query: 545 PGGYECDCDVGFTRAADGRSCLG 567
G + C + DGR+C G
Sbjct: 336 ADG-KTSCVCRESEVGDGRACYG 357
Score = 60.5 bits (140), Expect = 2e-08
Identities = 63/217 (29%), Positives = 84/217 (38%), Gaps = 20/217 (9%)
Query: 172 GDGDCHN-TEGSFTCHCRPGYKADDFSKICVDID---ECADNDALCRGGRCVNTAGSFR- 226
G G+C + +G+ C C P YK IC + + E D C G C N GS
Sbjct: 742 GKGNCSDGIQGNGACLCFPDYKGIA-CHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGV 800
Query: 227 CECGHGMELAPDRLSCKDIDECSITSGICSN----GACENQMGTYQCVCDEGYAQSTVKS 282
C+ G R + + +C T G+ + C +Q G +C C +G+ + S
Sbjct: 801 CQQGTCAPGFSGRFCNESMGDCGPT-GLAQHCHLHARCVSQEGVARCRCLDGF-EGDGFS 858
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGS---YHCTCREGWHLRADGRSCRDIDECAGGAR-PC 338
C + PGS +HCTC +GW DGR C IDEC R C
Sbjct: 859 CTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGW--SGDGRVCVAIDECELDVRGGC 916
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
+ VG CT L AG C ID C
Sbjct: 917 HTDALCSYVGPGQSRCTCKL--GFAGDGYQCSPIDPC 951
Score = 54.8 bits (126), Expect = 8e-07
Identities = 42/143 (29%), Positives = 57/143 (39%), Gaps = 11/143 (7%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDCHNTE-GSFTCHCRPGYKADDF 196
G TC C GY C +V+ C G C +C G TC C+ GY D
Sbjct: 1436 GASTCACAAGYS--GNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGD-- 1491
Query: 197 SKICVDIDECADNDALCR-GGRCVNTAGS-FRCECGHGMELAPDRLSCKDIDECSITSGI 254
++C +I+ C + C C+ T C C G R +C+ +D CS +G
Sbjct: 1492 GELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIR-TCELLDPCSKNNGG 1550
Query: 255 CSNGACENQMGTYQ--CVCDEGY 275
CS A G Q C CD +
Sbjct: 1551 CSPYATCKSTGDGQRTCTCDTAH 1573
Score = 51.6 bits (118), Expect = 7e-06
Identities = 59/227 (25%), Positives = 87/227 (38%), Gaps = 38/227 (16%)
Query: 169 GVC-GDGDCHNTE-GSFTCHCRPGY--------KADDFSKICVDIDECADNDALCRGGRC 218
GVC G G C + GS CHC G+ + + C + +CA LC+ G
Sbjct: 1338 GVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHG--LCQEG-- 1393
Query: 219 VNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICS-----NGAC-ENQMGTYQCVCD 272
G C C G + L C ITS C N C ++ G C C
Sbjct: 1394 --LQGDGSCVCNVGWQ----GLRCDQ----KITSPQCPRKCDPNANCVQDSAGASTCACA 1443
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDEC 331
GY+ + + +C PG CTC++G+ DG C++I+ C
Sbjct: 1444 AGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGY--MGDGELCQEINSC 1501
Query: 332 AGGARPCG-GGQCRNT-VGSYTCTCTDGLVPSAAGAKPTCQDIDECA 376
C +C T +C+C +G S G + TC+ +D C+
Sbjct: 1502 LIHHGGCHIHAECIPTGPQQVSCSCREGY--SGDGIR-TCELLDPCS 1545
Score = 48.0 bits (109), Expect = 9e-05
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 10/112 (8%)
Query: 140 GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDCHNTEGSFTCHCRPGYKADDFSK 198
G +C+C GYE D + T D+ C+ G C + +C TC C P Y+ D +S
Sbjct: 2073 GNSCECSLGYEGDGRVCTVADL--CQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWS- 2129
Query: 199 ICVDIDECAD--NDALCRGGRCVNTA-GSFRCECGHGMELAPDRLSCKDIDE 247
C + C D C++T + RCEC G D L C + E
Sbjct: 2130 -CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAG--YVGDGLQCLEESE 2178
Score = 39.9 bits (89), Expect = 0.024
Identities = 60/235 (25%), Positives = 74/235 (31%), Gaps = 27/235 (11%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVD-GVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C PGY S+ H C E G C DG N TC C+ ++ C
Sbjct: 100 CCPGYW-GSRCHECPGGAETPCNGHGTCLDGMDRNG----TCVCQENFRGS----AC--- 147
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID--ECSITSGICSNGAC- 260
EC D + G C + C HG L C +C C
Sbjct: 148 QECQDPNRF--GPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCP 205
Query: 261 ENQMGTYQ---CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWH 317
+N + + C C GY Q + Q S V+ G C C E +H
Sbjct: 206 QNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCS-VSPKGQAQCHCPENYH 264
Query: 318 LRADGRSCRDIDECAG--GARPCGGGQC-RNTVGSYTCTCTDGLVPSAAGAKPTC 369
DG C D C G P C G CTC GLV + A C
Sbjct: 265 --GDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGC 317
Score = 39.1 bits (87), Expect = 0.041
Identities = 62/225 (27%), Positives = 86/225 (38%), Gaps = 42/225 (18%)
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTV---------GSYTCTCTD 356
GS C CR G+ G +C + CA GA CR TV GS +C C +
Sbjct: 1991 GSGQCLCRSGFA----GTAC---ELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDE 2043
Query: 357 GLVPSAAGAKPTCQDI--DECADLISTIIMMSVD-ELQKSVDPQI---PELC--GAGSCH 408
G + Q + CA S + L D ++ +LC G G C
Sbjct: 2044 GWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCS 2103
Query: 409 -----NTIGSFV-CQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLP-GSFQC 460
+ +G+ V C C Y G +C + C G C A+C++ + +C
Sbjct: 2104 EHANCSQVGTMVTCTCLPDYE---GDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC 2160
Query: 461 RCRDGWRGDGATCED-----VDECLTNNGGCHPRATCANTDGSFR 500
C G+ GDG C + VD CL CH A C TD F+
Sbjct: 2161 ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMC--TDQHFQ 2203
Score = 35.1 bits (77), Expect = 0.67
Identities = 50/197 (25%), Positives = 68/197 (34%), Gaps = 24/197 (12%)
Query: 130 GHGRCRNLLG-GFTCDCFPGYEKDSKNHTCVDVN----ECEIVDGVCGDGDC-HNTEGSF 183
GHG C + + TC C + + S C D N +C+ V C G C H G
Sbjct: 122 GHGTCLDGMDRNGTCVCQENF-RGSACQECQDPNRFGPDCQSVCS-CVHGVCNHGPRGDG 179
Query: 184 TCHCRPGYKA---DDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
+C C GY D +C ++ C N +C A S RC G+ + +
Sbjct: 180 SCLCFAGYTGPHCDQELPVCQEL-RCPQNT------QCSAEAPSCRCLPGYTQQGS---- 228
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXXRCQH 299
C+ + C + + G QC C E Y V
Sbjct: 229 ECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNST 288
Query: 300 SCV-NTPGSYHCTCREG 315
CV PG CTCR G
Sbjct: 289 LCVYQKPGQAFCTCRPG 305
Score = 32.3 bits (70), Expect = 4.7
Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 5/71 (7%)
Query: 127 GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC-EIVDGVCGD-GDCHNTE-GSF 183
G H C + TC C P YE D +C N C + G C + +C +T +
Sbjct: 2101 GCSEHANCSQVGTMVTCTCLPDYEGD--GWSCRARNPCTDGHRGGCSEHANCLSTGLNTR 2158
Query: 184 TCHCRPGYKAD 194
C C GY D
Sbjct: 2159 RCECHAGYVGD 2169
Score = 31.9 bits (69), Expect = 6.2
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 4/61 (6%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSF-TCHCRPGYKADDF 196
G C C G+ D + C ++ C +G C G C G C C PG+ D F
Sbjct: 928 GQSRCTCKLGFAGDG--YQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGF 985
Query: 197 S 197
S
Sbjct: 986 S 986
>AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein.
Length = 2570
Score = 119 bits (287), Expect = 2e-26
Identities = 106/373 (28%), Positives = 147/373 (39%), Gaps = 50/373 (13%)
Query: 199 ICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG 258
+ V C + A +CVN FRC G ++ P R SC S + G CS
Sbjct: 1253 LTVGSSRCLHSHAEALREKCVNCTRRFRCTQGFQLQDTP-RKSCVYRSGFSFSRG-CSY- 1309
Query: 259 ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHL 318
C ++ C C G+ + + +CQ + GS C C EG+H
Sbjct: 1310 TCAKKIQVPDC-CP-GFFGTLCEPCPGGLGGVCSGHGQCQDRFL---GSGECHCHEGFH- 1363
Query: 319 RADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
G +C + C G G C C C GL +C
Sbjct: 1364 ---GTAC---EVCELGRY---GPNCTGV-----CDCAHGLCQEGLQGDGSC--------- 1400
Query: 379 ISTIIMMSVDELQKSVDPQIPELC--GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDD 436
+ + + QK PQ P C A ++ G+ C C GYS G C++ D
Sbjct: 1401 VCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYS---GNGIFCSEVD 1457
Query: 437 ECELGTCDCHPAADCINL-PGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANT 495
C G C P A+C + PG C C+DG+ GDG C++++ CL ++GGCH A C T
Sbjct: 1458 PCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPT 1517
Query: 496 -DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYE-CDC 552
C C GY GD G+RT C +D C+ + C C +T G C C
Sbjct: 1518 GPQQVSCSCREGYSGD--GIRT------CELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
Query: 553 DVGFTRAADGRSC 565
D T DG +C
Sbjct: 1570 DTAHT-VGDGLTC 1581
Score = 89.8 bits (213), Expect = 2e-17
Identities = 71/224 (31%), Positives = 88/224 (39%), Gaps = 26/224 (11%)
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ-IPELCGAGS-CHN 409
C C GL + G+ CQ CA S +E P + + C + C +
Sbjct: 784 CGCVHGLCDNRPGSGGVCQQ-GTCAPGFSGRFC---NESMGDCGPTGLAQHCHLHARCVS 839
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECEL-GTCDCHPAADCI-NLPGSFQCRCRDGWR 467
G C+C DG+ G +CT + C C A+C+ G+ C C GW
Sbjct: 840 QEGVARCRCLDGFE---GDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWS 896
Query: 468 GDGATCEDVDEC-LTNNGGCHPRATCANTD-GSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
GDG C +DEC L GGCH A C+ G RC C G+ GDGY C
Sbjct: 897 GDGRVCVAIDECELDVGGGCHTDALCSYVGPGQSRCTCKLGFAGDGY---------QCSP 947
Query: 526 IDECANDPTLCEN-GHCSNTPGGYE-CDCDVGFTRAADGRSCLG 567
ID C C C GG C C GF DG SC G
Sbjct: 948 IDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF--GGDGFSCYG 989
Score = 80.6 bits (190), Expect = 1e-14
Identities = 80/259 (30%), Positives = 101/259 (38%), Gaps = 26/259 (10%)
Query: 118 EVNEC-AAFPGLC-GHGRCRN-LLGGFTCDCFPGYEKDSKNHTCVDVN----ECEIVDGV 170
+ +C F C G G C + + G C CFP Y K H C + N +C+ D
Sbjct: 728 DCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDY-KGIACHICSNPNKHGEQCQ-EDCG 785
Query: 171 CGDGDCHNTEGSFTCHCRPGYKADDFS-KICVD-IDECADNDAL--CR-GGRCVNTAGSF 225
C G C N GS C+ G A FS + C + + +C C RCV+ G
Sbjct: 786 CVHGLCDNRPGSGGV-CQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVA 844
Query: 226 RCECGHGMELAPDRLSCKDIDECSITS-GICS-NGAC-ENQMGTYQCVCDEGYA-QSTVK 281
RC C G E D SC + CS G CS N C +GT+ C C +G++ V
Sbjct: 845 RCRCLDGFE--GDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVC 902
Query: 282 SHXXXXXXXXXXXXRCQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG 340
C PG CTC+ G+ DG C ID C G C G
Sbjct: 903 VAIDECELDVGGGCHTDALCSYVGPGQSRCTCKLGF--AGDGYQCSPIDPCRAGNGGCHG 960
Query: 341 -GQCRNTVGSY-TCTCTDG 357
CR G CTC G
Sbjct: 961 LATCRAVGGGQRVCTCPPG 979
Score = 79.4 bits (187), Expect = 3e-14
Identities = 66/183 (36%), Positives = 81/183 (44%), Gaps = 30/183 (16%)
Query: 397 QIPELCGA--GSCHNTIGSF-VCQ---CPDGYSVKPEQGPACTDD-DEC-ELGTCD-CHP 447
Q E CG G C N GS VCQ C G+S G C + +C G CH
Sbjct: 779 QCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS-----GRFCNESMGDCGPTGLAQHCHL 833
Query: 448 AADCINLPGSFQCRCRDGWRGDGATCEDVDECL-TNNGGCHPRATCA-NTDGSFRCLCDT 505
A C++ G +CRC DG+ GDG +C + C + GGC A C + G+ C C
Sbjct: 834 HARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHK 893
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECAND-PTLCE-NGHCSNT-PGGYECDCDVGFTRAADG 562
G+ GDG CV IDEC D C + CS PG C C +GF A DG
Sbjct: 894 GWSGDG---------RVCVAIDECELDVGGGCHTDALCSYVGPGQSRCTCKLGF--AGDG 942
Query: 563 RSC 565
C
Sbjct: 943 YQC 945
Score = 67.3 bits (157), Expect = 1e-10
Identities = 49/165 (29%), Positives = 66/165 (40%), Gaps = 20/165 (12%)
Query: 405 GSCHNTIG-SFVCQCPDGYSVKPEQGPACTDDDECE-LGTCDCHPAADCINLPGSFQCRC 462
G C +G S C C +G++ GP C E + + T C P A C C C
Sbjct: 2027 GRCDEGLGGSGSCFCDEGWT-----GPRCEVQLELQPVCTPPCAPEAVC---RAGNSCEC 2078
Query: 463 RDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ GDG C D C +GGC A C+ C C Y+GDG+ R
Sbjct: 2079 SLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCR---ARNP 2135
Query: 523 CVDIDECANDPTLCENGHCSNTP-GGYECDCDVGFTRAADGRSCL 566
C D + E+ +C +T C+C G+ DG CL
Sbjct: 2136 CTD----GHRGGCSEHANCLSTGLNTRRCECHAGY--VGDGLQCL 2174
Score = 63.3 bits (147), Expect = 2e-09
Identities = 45/151 (29%), Positives = 61/151 (40%), Gaps = 10/151 (6%)
Query: 131 HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVD-GVCGDG-DC-HNTEGSFTCHC 187
H RC + G C C G+E D +C N C D G C + +C + G+ C C
Sbjct: 834 HARCVSQEGVARCRCLDGFEGDG--FSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTC 891
Query: 188 RPGYKADDFSKICVDIDECA-DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
G+ D ++CV IDEC D C + G + C + A D C ID
Sbjct: 892 HKGWSGD--GRVCVAIDECELDVGGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPID 949
Query: 247 ECSITSGICSNGACENQMGTYQ--CVCDEGY 275
C +G C A +G Q C C G+
Sbjct: 950 PCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
Score = 61.7 bits (143), Expect = 7e-09
Identities = 71/263 (26%), Positives = 95/263 (36%), Gaps = 41/263 (15%)
Query: 330 ECAGGAR-PCGG-GQCRNTVG-SYTCTCTDGLVPSAAGA-------KPTCQDIDECADLI 379
EC GGA PC G G C + + + TC C + SA P CQ + C +
Sbjct: 111 ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGV 170
Query: 380 ST-------IIMMSVDELQKSVDPQIPELCGAGSC-HNTIGSFV---CQCPDGYSVKPEQ 428
+ D ++P +C C NT S C+C GY+ +Q
Sbjct: 171 CNHGPRGDGSCLCFAGYTGPHCDQELP-VCQELRCPQNTQCSAEAPSCRCLPGYT---QQ 226
Query: 429 GPACTDDDECELGTCDCHPAADCINLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCH 487
G C + C C A C P G QC C + + GDG C D C N GGC
Sbjct: 227 GSECRAPNPCWPSPCSL--LAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCP 284
Query: 488 PRAT-CA-NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNT 544
+T C G C C G C + C+ P C+ + C T
Sbjct: 285 SNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAF-------CS--PFSCDRSATCQVT 335
Query: 545 PGGYECDCDVGFTRAADGRSCLG 567
G + C + DGR+C G
Sbjct: 336 ADG-KTSCVCRESEVGDGRACYG 357
Score = 61.3 bits (142), Expect = 9e-09
Identities = 65/222 (29%), Positives = 87/222 (39%), Gaps = 30/222 (13%)
Query: 172 GDGDCHN-TEGSFTCHCRPGYKADDFSKICVDID---ECADNDALCRGGRCVNTAGSFR- 226
G G+C + +G+ C C P YK IC + + E D C G C N GS
Sbjct: 742 GKGNCSDGIQGNGACLCFPDYKGIA-CHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGV 800
Query: 227 CECGHGMELAPDRLSCKDIDECSITSGICSN----GACENQMGTYQCVCDEGYAQSTVKS 282
C+ G R + + +C T G+ + C +Q G +C C +G+ + S
Sbjct: 801 CQQGTCAPGFSGRFCNESMGDCGPT-GLAQHCHLHARCVSQEGVARCRCLDGF-EGDGFS 858
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGS---YHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
C + PGS +HCTC +GW DGR C IDEC G
Sbjct: 859 CTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGW--SGDGRVCVAIDEC---ELDVG 913
Query: 340 GGQCRNTVGSYT------CTCTDGLVPSAAGAKPTCQDIDEC 375
GG + + SY CTC G AG C ID C
Sbjct: 914 GGCHTDALCSYVGPGQSRCTCKLGF----AGDGYQCSPIDPC 951
Score = 54.8 bits (126), Expect = 8e-07
Identities = 42/143 (29%), Positives = 57/143 (39%), Gaps = 11/143 (7%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDCHNTE-GSFTCHCRPGYKADDF 196
G TC C GY C +V+ C G C +C G TC C+ GY D
Sbjct: 1436 GASTCACAAGYS--GNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGD-- 1491
Query: 197 SKICVDIDECADNDALCR-GGRCVNTAGS-FRCECGHGMELAPDRLSCKDIDECSITSGI 254
++C +I+ C + C C+ T C C G R +C+ +D CS +G
Sbjct: 1492 GELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIR-TCELLDPCSKNNGG 1550
Query: 255 CSNGACENQMGTYQ--CVCDEGY 275
CS A G Q C CD +
Sbjct: 1551 CSPYATCKSTGDGQRTCTCDTAH 1573
Score = 51.6 bits (118), Expect = 7e-06
Identities = 59/227 (25%), Positives = 87/227 (38%), Gaps = 38/227 (16%)
Query: 169 GVC-GDGDCHNTE-GSFTCHCRPGY--------KADDFSKICVDIDECADNDALCRGGRC 218
GVC G G C + GS CHC G+ + + C + +CA LC+ G
Sbjct: 1338 GVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHG--LCQEG-- 1393
Query: 219 VNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICS-----NGAC-ENQMGTYQCVCD 272
G C C G + L C ITS C N C ++ G C C
Sbjct: 1394 --LQGDGSCVCNVGWQ----GLRCDQ----KITSPQCPRKCDPNANCVQDSAGASTCACA 1443
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDEC 331
GY+ + + +C PG CTC++G+ DG C++I+ C
Sbjct: 1444 AGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGY--MGDGELCQEINSC 1501
Query: 332 AGGARPCG-GGQCRNT-VGSYTCTCTDGLVPSAAGAKPTCQDIDECA 376
C +C T +C+C +G S G + TC+ +D C+
Sbjct: 1502 LIHHGGCHIHAECIPTGPQQVSCSCREGY--SGDGIR-TCELLDPCS 1545
Score = 48.0 bits (109), Expect = 9e-05
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 10/112 (8%)
Query: 140 GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDCHNTEGSFTCHCRPGYKADDFSK 198
G +C+C GYE D + T D+ C+ G C + +C TC C P Y+ D +S
Sbjct: 2073 GNSCECSLGYEGDGRVCTVADL--CQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWS- 2129
Query: 199 ICVDIDECAD--NDALCRGGRCVNTA-GSFRCECGHGMELAPDRLSCKDIDE 247
C + C D C++T + RCEC G D L C + E
Sbjct: 2130 -CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAG--YVGDGLQCLEESE 2178
Score = 39.9 bits (89), Expect = 0.024
Identities = 60/235 (25%), Positives = 74/235 (31%), Gaps = 27/235 (11%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVD-GVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C PGY S+ H C E G C DG N TC C+ ++ C
Sbjct: 100 CCPGYW-GSRCHECPGGAETPCNGHGTCLDGMDRNG----TCVCQENFRGS----AC--- 147
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID--ECSITSGICSNGAC- 260
EC D + G C + C HG L C +C C
Sbjct: 148 QECQDPNRF--GPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCP 205
Query: 261 ENQMGTYQ---CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWH 317
+N + + C C GY Q + Q S V+ G C C E +H
Sbjct: 206 QNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCS-VSPKGQAQCHCPENYH 264
Query: 318 LRADGRSCRDIDECAG--GARPCGGGQC-RNTVGSYTCTCTDGLVPSAAGAKPTC 369
DG C D C G P C G CTC GLV + A C
Sbjct: 265 --GDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGC 317
Score = 39.1 bits (87), Expect = 0.041
Identities = 62/225 (27%), Positives = 86/225 (38%), Gaps = 42/225 (18%)
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTV---------GSYTCTCTD 356
GS C CR G+ G +C + CA GA CR TV GS +C C +
Sbjct: 1991 GSGQCLCRSGFA----GTAC---ELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDE 2043
Query: 357 GLVPSAAGAKPTCQDI--DECADLISTIIMMSVD-ELQKSVDPQI---PELC--GAGSCH 408
G + Q + CA S + L D ++ +LC G G C
Sbjct: 2044 GWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCS 2103
Query: 409 -----NTIGSFV-CQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLP-GSFQC 460
+ +G+ V C C Y G +C + C G C A+C++ + +C
Sbjct: 2104 EHANCSQVGTMVTCTCLPDYE---GDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC 2160
Query: 461 RCRDGWRGDGATCED-----VDECLTNNGGCHPRATCANTDGSFR 500
C G+ GDG C + VD CL CH A C TD F+
Sbjct: 2161 ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMC--TDQHFQ 2203
Score = 35.1 bits (77), Expect = 0.67
Identities = 50/197 (25%), Positives = 68/197 (34%), Gaps = 24/197 (12%)
Query: 130 GHGRCRNLLG-GFTCDCFPGYEKDSKNHTCVDVN----ECEIVDGVCGDGDC-HNTEGSF 183
GHG C + + TC C + + S C D N +C+ V C G C H G
Sbjct: 122 GHGTCLDGMDRNGTCVCQENF-RGSACQECQDPNRFGPDCQSVCS-CVHGVCNHGPRGDG 179
Query: 184 TCHCRPGYKA---DDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
+C C GY D +C ++ C N +C A S RC G+ + +
Sbjct: 180 SCLCFAGYTGPHCDQELPVCQEL-RCPQNT------QCSAEAPSCRCLPGYTQQGS---- 228
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXXRCQH 299
C+ + C + + G QC C E Y V
Sbjct: 229 ECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNST 288
Query: 300 SCV-NTPGSYHCTCREG 315
CV PG CTCR G
Sbjct: 289 LCVYQKPGQAFCTCRPG 305
Score = 32.3 bits (70), Expect = 4.7
Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 5/71 (7%)
Query: 127 GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC-EIVDGVCGD-GDCHNTE-GSF 183
G H C + TC C P YE D +C N C + G C + +C +T +
Sbjct: 2101 GCSEHANCSQVGTMVTCTCLPDYEGD--GWSCRARNPCTDGHRGGCSEHANCLSTGLNTR 2158
Query: 184 TCHCRPGYKAD 194
C C GY D
Sbjct: 2159 RCECHAGYVGD 2169
Score = 31.9 bits (69), Expect = 6.2
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 4/61 (6%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSF-TCHCRPGYKADDF 196
G C C G+ D + C ++ C +G C G C G C C PG+ D F
Sbjct: 928 GQSRCTCKLGFAGDG--YQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGF 985
Query: 197 S 197
S
Sbjct: 986 S 986
>AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein.
Length = 2570
Score = 119 bits (287), Expect = 2e-26
Identities = 106/373 (28%), Positives = 147/373 (39%), Gaps = 50/373 (13%)
Query: 199 ICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG 258
+ V C + A +CVN FRC G ++ P R SC S + G CS
Sbjct: 1253 LTVGSSRCLHSHAEALREKCVNCTRRFRCTQGFQLQDTP-RKSCVYRSGFSFSRG-CSY- 1309
Query: 259 ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHL 318
C ++ C C G+ + + +CQ + GS C C EG+H
Sbjct: 1310 TCAKKIQVPDC-CP-GFFGTLCEPCPGGLGGVCSGHGQCQDRFL---GSGECHCHEGFH- 1363
Query: 319 RADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
G +C + C G G C C C GL +C
Sbjct: 1364 ---GTAC---EVCELGRY---GPNCTGV-----CDCAHGLCQEGLQGDGSC--------- 1400
Query: 379 ISTIIMMSVDELQKSVDPQIPELC--GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDD 436
+ + + QK PQ P C A ++ G+ C C GYS G C++ D
Sbjct: 1401 VCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYS---GNGIFCSEVD 1457
Query: 437 ECELGTCDCHPAADCINL-PGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANT 495
C G C P A+C + PG C C+DG+ GDG C++++ CL ++GGCH A C T
Sbjct: 1458 PCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPT 1517
Query: 496 -DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGYE-CDC 552
C C GY GD G+RT C +D C+ + C C +T G C C
Sbjct: 1518 GPQQVSCSCREGYSGD--GIRT------CELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
Query: 553 DVGFTRAADGRSC 565
D T DG +C
Sbjct: 1570 DTAHT-VGDGLTC 1581
Score = 89.8 bits (213), Expect = 2e-17
Identities = 71/224 (31%), Positives = 88/224 (39%), Gaps = 26/224 (11%)
Query: 352 CTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQ-IPELCGAGS-CHN 409
C C GL + G+ CQ CA S +E P + + C + C +
Sbjct: 784 CGCVHGLCDNRPGSGGVCQQ-GTCAPGFSGRFC---NESMGDCGPTGLAQHCHLHARCVS 839
Query: 410 TIGSFVCQCPDGYSVKPEQGPACTDDDECEL-GTCDCHPAADCI-NLPGSFQCRCRDGWR 467
G C+C DG+ G +CT + C C A+C+ G+ C C GW
Sbjct: 840 QEGVARCRCLDGFE---GDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWS 896
Query: 468 GDGATCEDVDEC-LTNNGGCHPRATCANTD-GSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
GDG C +DEC L GGCH A C+ G RC C G+ GDGY C
Sbjct: 897 GDGRVCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGY---------QCSP 947
Query: 526 IDECANDPTLCEN-GHCSNTPGGYE-CDCDVGFTRAADGRSCLG 567
ID C C C GG C C GF DG SC G
Sbjct: 948 IDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF--GGDGFSCYG 989
Score = 80.6 bits (190), Expect = 1e-14
Identities = 80/259 (30%), Positives = 101/259 (38%), Gaps = 26/259 (10%)
Query: 118 EVNEC-AAFPGLC-GHGRCRN-LLGGFTCDCFPGYEKDSKNHTCVDVN----ECEIVDGV 170
+ +C F C G G C + + G C CFP Y K H C + N +C+ D
Sbjct: 728 DCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDY-KGIACHICSNPNKHGEQCQ-EDCG 785
Query: 171 CGDGDCHNTEGSFTCHCRPGYKADDFS-KICVD-IDECADNDAL--CR-GGRCVNTAGSF 225
C G C N GS C+ G A FS + C + + +C C RCV+ G
Sbjct: 786 CVHGLCDNRPGSGGV-CQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVA 844
Query: 226 RCECGHGMELAPDRLSCKDIDECSITS-GICS-NGAC-ENQMGTYQCVCDEGYA-QSTVK 281
RC C G E D SC + CS G CS N C +GT+ C C +G++ V
Sbjct: 845 RCRCLDGFE--GDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVC 902
Query: 282 SHXXXXXXXXXXXXRCQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG 340
C PG CTC+ G+ DG C ID C G C G
Sbjct: 903 VAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGF--AGDGYQCSPIDPCRAGNGGCHG 960
Query: 341 -GQCRNTVGSY-TCTCTDG 357
CR G CTC G
Sbjct: 961 LATCRAVGGGQRVCTCPPG 979
Score = 79.8 bits (188), Expect = 2e-14
Identities = 66/183 (36%), Positives = 81/183 (44%), Gaps = 30/183 (16%)
Query: 397 QIPELCGA--GSCHNTIGSF-VCQ---CPDGYSVKPEQGPACTDD-DEC-ELGTCD-CHP 447
Q E CG G C N GS VCQ C G+S G C + +C G CH
Sbjct: 779 QCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS-----GRFCNESMGDCGPTGLAQHCHL 833
Query: 448 AADCINLPGSFQCRCRDGWRGDGATCEDVDECL-TNNGGCHPRATCA-NTDGSFRCLCDT 505
A C++ G +CRC DG+ GDG +C + C + GGC A C + G+ C C
Sbjct: 834 HARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHK 893
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPT-LCE-NGHCSNT-PGGYECDCDVGFTRAADG 562
G+ GDG CV IDEC D C + CS PG C C +GF A DG
Sbjct: 894 GWSGDG---------RVCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGF--AGDG 942
Query: 563 RSC 565
C
Sbjct: 943 YQC 945
Score = 67.3 bits (157), Expect = 1e-10
Identities = 49/165 (29%), Positives = 66/165 (40%), Gaps = 20/165 (12%)
Query: 405 GSCHNTIG-SFVCQCPDGYSVKPEQGPACTDDDECE-LGTCDCHPAADCINLPGSFQCRC 462
G C +G S C C +G++ GP C E + + T C P A C C C
Sbjct: 2027 GRCDEGLGGSGSCFCDEGWT-----GPRCEVQLELQPVCTPPCAPEAVC---RAGNSCEC 2078
Query: 463 RDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYS 522
G+ GDG C D C +GGC A C+ C C Y+GDG+ R
Sbjct: 2079 SLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCR---ARNP 2135
Query: 523 CVDIDECANDPTLCENGHCSNTP-GGYECDCDVGFTRAADGRSCL 566
C D + E+ +C +T C+C G+ DG CL
Sbjct: 2136 CTD----GHRGGCSEHANCLSTGLNTRRCECHAGY--VGDGLQCL 2174
Score = 62.9 bits (146), Expect = 3e-09
Identities = 45/151 (29%), Positives = 61/151 (40%), Gaps = 10/151 (6%)
Query: 131 HGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVD-GVCGDG-DC-HNTEGSFTCHC 187
H RC + G C C G+E D +C N C D G C + +C + G+ C C
Sbjct: 834 HARCVSQEGVARCRCLDGFEGDG--FSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTC 891
Query: 188 RPGYKADDFSKICVDIDECA-DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
G+ D ++CV IDEC D C + G + C + A D C ID
Sbjct: 892 HKGWSGD--GRVCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPID 949
Query: 247 ECSITSGICSNGACENQMGTYQ--CVCDEGY 275
C +G C A +G Q C C G+
Sbjct: 950 PCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
Score = 61.7 bits (143), Expect = 7e-09
Identities = 71/263 (26%), Positives = 95/263 (36%), Gaps = 41/263 (15%)
Query: 330 ECAGGAR-PCGG-GQCRNTVG-SYTCTCTDGLVPSAAGA-------KPTCQDIDECADLI 379
EC GGA PC G G C + + + TC C + SA P CQ + C +
Sbjct: 111 ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGV 170
Query: 380 ST-------IIMMSVDELQKSVDPQIPELCGAGSC-HNTIGSFV---CQCPDGYSVKPEQ 428
+ D ++P +C C NT S C+C GY+ +Q
Sbjct: 171 CNHGPRGDGSCLCFAGYTGPHCDQELP-VCQELRCPQNTQCSAEAPSCRCLPGYT---QQ 226
Query: 429 GPACTDDDECELGTCDCHPAADCINLP-GSFQCRCRDGWRGDGATCEDVDECLTNNGGCH 487
G C + C C A C P G QC C + + GDG C D C N GGC
Sbjct: 227 GSECRAPNPCWPSPCSL--LAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCP 284
Query: 488 PRAT-CA-NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNT 544
+T C G C C G C + C+ P C+ + C T
Sbjct: 285 SNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAF-------CS--PFSCDRSATCQVT 335
Query: 545 PGGYECDCDVGFTRAADGRSCLG 567
G + C + DGR+C G
Sbjct: 336 ADG-KTSCVCRESEVGDGRACYG 357
Score = 60.5 bits (140), Expect = 2e-08
Identities = 63/217 (29%), Positives = 84/217 (38%), Gaps = 20/217 (9%)
Query: 172 GDGDCHN-TEGSFTCHCRPGYKADDFSKICVDID---ECADNDALCRGGRCVNTAGSFR- 226
G G+C + +G+ C C P YK IC + + E D C G C N GS
Sbjct: 742 GKGNCSDGIQGNGACLCFPDYKGIA-CHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGV 800
Query: 227 CECGHGMELAPDRLSCKDIDECSITSGICSN----GACENQMGTYQCVCDEGYAQSTVKS 282
C+ G R + + +C T G+ + C +Q G +C C +G+ + S
Sbjct: 801 CQQGTCAPGFSGRFCNESMGDCGPT-GLAQHCHLHARCVSQEGVARCRCLDGF-EGDGFS 858
Query: 283 HXXXXXXXXXXXXRCQHSCVNTPGS---YHCTCREGWHLRADGRSCRDIDECAGGAR-PC 338
C + PGS +HCTC +GW DGR C IDEC R C
Sbjct: 859 CTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGW--SGDGRVCVAIDECELDVRGGC 916
Query: 339 GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
+ VG CT L AG C ID C
Sbjct: 917 HTDALCSYVGPGQSRCTCKL--GFAGDGYQCSPIDPC 951
Score = 54.8 bits (126), Expect = 8e-07
Identities = 42/143 (29%), Positives = 57/143 (39%), Gaps = 11/143 (7%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDCHNTE-GSFTCHCRPGYKADDF 196
G TC C GY C +V+ C G C +C G TC C+ GY D
Sbjct: 1436 GASTCACAAGYS--GNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGD-- 1491
Query: 197 SKICVDIDECADNDALCR-GGRCVNTAGS-FRCECGHGMELAPDRLSCKDIDECSITSGI 254
++C +I+ C + C C+ T C C G R +C+ +D CS +G
Sbjct: 1492 GELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIR-TCELLDPCSKNNGG 1550
Query: 255 CSNGACENQMGTYQ--CVCDEGY 275
CS A G Q C CD +
Sbjct: 1551 CSPYATCKSTGDGQRTCTCDTAH 1573
Score = 51.6 bits (118), Expect = 7e-06
Identities = 59/227 (25%), Positives = 87/227 (38%), Gaps = 38/227 (16%)
Query: 169 GVC-GDGDCHNTE-GSFTCHCRPGY--------KADDFSKICVDIDECADNDALCRGGRC 218
GVC G G C + GS CHC G+ + + C + +CA LC+ G
Sbjct: 1338 GVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHG--LCQEG-- 1393
Query: 219 VNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICS-----NGAC-ENQMGTYQCVCD 272
G C C G + L C ITS C N C ++ G C C
Sbjct: 1394 --LQGDGSCVCNVGWQ----GLRCDQ----KITSPQCPRKCDPNANCVQDSAGASTCACA 1443
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDEC 331
GY+ + + +C PG CTC++G+ DG C++I+ C
Sbjct: 1444 AGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGY--MGDGELCQEINSC 1501
Query: 332 AGGARPCG-GGQCRNT-VGSYTCTCTDGLVPSAAGAKPTCQDIDECA 376
C +C T +C+C +G S G + TC+ +D C+
Sbjct: 1502 LIHHGGCHIHAECIPTGPQQVSCSCREGY--SGDGIR-TCELLDPCS 1545
Score = 48.0 bits (109), Expect = 9e-05
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 10/112 (8%)
Query: 140 GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGD-GDCHNTEGSFTCHCRPGYKADDFSK 198
G +C+C GYE D + T D+ C+ G C + +C TC C P Y+ D +S
Sbjct: 2073 GNSCECSLGYEGDGRVCTVADL--CQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWS- 2129
Query: 199 ICVDIDECAD--NDALCRGGRCVNTA-GSFRCECGHGMELAPDRLSCKDIDE 247
C + C D C++T + RCEC G D L C + E
Sbjct: 2130 -CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAG--YVGDGLQCLEESE 2178
Score = 39.9 bits (89), Expect = 0.024
Identities = 60/235 (25%), Positives = 74/235 (31%), Gaps = 27/235 (11%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVD-GVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
C PGY S+ H C E G C DG N TC C+ ++ C
Sbjct: 100 CCPGYW-GSRCHECPGGAETPCNGHGTCLDGMDRNG----TCVCQENFRGS----AC--- 147
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID--ECSITSGICSNGAC- 260
EC D + G C + C HG L C +C C
Sbjct: 148 QECQDPNRF--GPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCP 205
Query: 261 ENQMGTYQ---CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWH 317
+N + + C C GY Q + Q S V+ G C C E +H
Sbjct: 206 QNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCS-VSPKGQAQCHCPENYH 264
Query: 318 LRADGRSCRDIDECAG--GARPCGGGQC-RNTVGSYTCTCTDGLVPSAAGAKPTC 369
DG C D C G P C G CTC GLV + A C
Sbjct: 265 --GDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGC 317
Score = 38.7 bits (86), Expect = 0.054
Identities = 59/219 (26%), Positives = 83/219 (37%), Gaps = 40/219 (18%)
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTV---------GSYTCTCTD 356
GS C CR G+ G +C + CA GA CR TV GS +C C +
Sbjct: 1991 GSGQCLCRSGFA----GTAC---ELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDE 2043
Query: 357 GLVPSAAGAKPTCQDI--DECADLISTIIMMSVD-ELQKSVDPQI---PELC--GAGSCH 408
G + Q + CA S + L D ++ +LC G G C
Sbjct: 2044 GWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCS 2103
Query: 409 -----NTIGSFV-CQCPDGYSVKPEQGPACTDDDECELG-TCDCHPAADCINLP-GSFQC 460
+ +G+ V C C Y G +C + C G C A+C++ + +C
Sbjct: 2104 EHANCSQVGTMVTCTCLPDYE---GDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC 2160
Query: 461 RCRDGWRGDGATCED-----VDECLTNNGGCHPRATCAN 494
C G+ GDG C + VD CL CH A C +
Sbjct: 2161 ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTD 2199
Score = 35.1 bits (77), Expect = 0.67
Identities = 50/197 (25%), Positives = 68/197 (34%), Gaps = 24/197 (12%)
Query: 130 GHGRCRNLLG-GFTCDCFPGYEKDSKNHTCVDVN----ECEIVDGVCGDGDC-HNTEGSF 183
GHG C + + TC C + + S C D N +C+ V C G C H G
Sbjct: 122 GHGTCLDGMDRNGTCVCQENF-RGSACQECQDPNRFGPDCQSVCS-CVHGVCNHGPRGDG 179
Query: 184 TCHCRPGYKA---DDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
+C C GY D +C ++ C N +C A S RC G+ + +
Sbjct: 180 SCLCFAGYTGPHCDQELPVCQEL-RCPQNT------QCSAEAPSCRCLPGYTQQGS---- 228
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXXRCQH 299
C+ + C + + G QC C E Y V
Sbjct: 229 ECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNST 288
Query: 300 SCV-NTPGSYHCTCREG 315
CV PG CTCR G
Sbjct: 289 LCVYQKPGQAFCTCRPG 305
Score = 32.3 bits (70), Expect = 4.7
Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 5/71 (7%)
Query: 127 GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC-EIVDGVCGD-GDCHNTE-GSF 183
G H C + TC C P YE D +C N C + G C + +C +T +
Sbjct: 2101 GCSEHANCSQVGTMVTCTCLPDYEGD--GWSCRARNPCTDGHRGGCSEHANCLSTGLNTR 2158
Query: 184 TCHCRPGYKAD 194
C C GY D
Sbjct: 2159 RCECHAGYVGD 2169
Score = 31.9 bits (69), Expect = 6.2
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 4/61 (6%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC-GDGDCHNTEGSF-TCHCRPGYKADDF 196
G C C G+ D + C ++ C +G C G C G C C PG+ D F
Sbjct: 928 GQSRCTCKLGFAGDG--YQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGF 985
Query: 197 S 197
S
Sbjct: 986 S 986
>AF054501-1|AAC39881.1| 161|Homo sapiens latent transforming growth
factor-beta binding protein 4 protein.
Length = 161
Score = 118 bits (285), Expect = 4e-26
Identities = 58/147 (39%), Positives = 73/147 (49%), Gaps = 4/147 (2%)
Query: 128 LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC-EIVDGVCGDGDCHNTEGSFTC- 185
LC G C N G F C C PG+ +C+DV+EC E +CG C N+ GS+ C
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 60
Query: 186 -HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD 244
C PGY A C D+DEC + C N GSF+C C G E A D C D
Sbjct: 61 RDCDPGYHAGP-EGTCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 119
Query: 245 IDECSITSGICSNGACENQMGTYQCVC 271
++EC G+C CEN G++ CVC
Sbjct: 120 VNECETLQGVCGAALCENVEGSFLCVC 146
Score = 117 bits (281), Expect = 1e-25
Identities = 65/156 (41%), Positives = 80/156 (51%), Gaps = 14/156 (8%)
Query: 401 LCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC-ELGTCDCHPAADCINLPGSFQ 459
LC +G C NT GSF C CP G+ P+ +C D DEC E G C + C N PGS++
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLA-SCLDVDECRERGPALC-GSQRCENSPGSYR 58
Query: 460 C--RCRDGWR-GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRT 516
C C G+ G TC+DVDEC N C A C N GSF+CLCD GY+G G
Sbjct: 59 CVRDCDPGYHAGPEGTCDDVDEC-RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRH- 116
Query: 517 VCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDC 552
CVD++EC +C C N G + C C
Sbjct: 117 ------CVDVNECETLQGVCGAALCENVEGSFLCVC 146
Score = 116 bits (280), Expect = 2e-25
Identities = 55/146 (37%), Positives = 68/146 (46%), Gaps = 3/146 (2%)
Query: 212 LCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITS-GICSNGACENQMGTYQCV 270
LC+ G C NT GSF C C G PD SC D+DEC +C + CEN G+Y+CV
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 60
Query: 271 --CDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDI 328
CD GY + C N PGS+ C C +G+ DGR C D+
Sbjct: 61 RDCDPGYHAGPEGTCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV 120
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTC 354
+EC CG C N GS+ C C
Sbjct: 121 NECETLQGVCGAALCENVEGSFLCVC 146
Score = 90.6 bits (215), Expect = 1e-17
Identities = 46/121 (38%), Positives = 58/121 (47%), Gaps = 4/121 (3%)
Query: 117 MEVNECAAF-PGLCGHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGD 173
++V+EC P LCG RC N G + C DC PGY + TC DV+EC
Sbjct: 32 LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECRNRSFCGAH 90
Query: 174 GDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C N GSF C C GY+ + CVD++EC +C C N GSF C C +
Sbjct: 91 AVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSP 150
Query: 234 E 234
E
Sbjct: 151 E 151
Score = 89.4 bits (212), Expect = 3e-17
Identities = 47/120 (39%), Positives = 59/120 (49%), Gaps = 12/120 (10%)
Query: 451 CINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCHPRATCANTDGSFRCL--CDTG 506
C N GSF+C C G R D A+C DVDEC C N+ GS+RC+ CD G
Sbjct: 7 CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPG 66
Query: 507 YKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
Y G +C D+DEC N + C N PG ++C CD G+ A DGR C+
Sbjct: 67 YHAGPEG--------TCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV 118
Score = 81.8 bits (193), Expect = 6e-15
Identities = 53/172 (30%), Positives = 75/172 (43%), Gaps = 29/172 (16%)
Query: 254 ICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXXRC-QHSCVNTPGSYHCT 311
+C +G C N G+++C+C G+ A + S C C N+PGSY C
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 60
Query: 312 --CREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTCTDGLVPSAAGAKPT 368
C G+H +G +C D+DEC + CG C+N GS+ C C G + G
Sbjct: 61 RDCDPGYHAGPEG-TCDDVDECRNRSF-CGAHAVCQNLPGSFQCLCDQGYEGARDGRH-- 116
Query: 369 CQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD 420
C D++EC L +CGA C N GSF+C CP+
Sbjct: 117 CVDVNECETLQG--------------------VCGAALCENVEGSFLCVCPN 148
Score = 38.3 bits (85), Expect = 0.072
Identities = 15/32 (46%), Positives = 19/32 (59%)
Query: 535 LCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
LC++G C+NT G +EC C G D SCL
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCL 32
>AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.
Length = 1282
Score = 116 bits (279), Expect = 2e-25
Identities = 112/425 (26%), Positives = 160/425 (37%), Gaps = 59/425 (13%)
Query: 158 CVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR 217
C+ + C + G C D DC S+TC C G+ + +D++ECA GG
Sbjct: 141 CLALRPC-LNGGKCID-DCVTGNPSYTCSCLSGFTG---RRCHLDVNECASQPCQ-NGGT 194
Query: 218 CVNTAGSFRCEC--GHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C + SFRC+C G G S D EC G C+ + G+ CVC GY
Sbjct: 195 CTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQ------HGGQCQVENGSAVCVCQAGY 248
Query: 276 AQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWH-LRADGRSCRDIDECAGG 334
+ + SCV+ G+Y C C E + LR + D C
Sbjct: 249 TGAACEMDVDDCSPDPCLNG---GSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACL-- 303
Query: 335 ARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKP----TCQDIDECADLISTIIMMSVD- 388
+ PC GG C + Y C C +G + + C++ C +T+ +
Sbjct: 304 SAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGF 363
Query: 389 -----ELQKSVDP-QIPELC-GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELG 441
E + + P + C G C GS++C C ++ C D G
Sbjct: 364 FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGG 423
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRC 501
+CD H S+ C C G+ G CE L ++G C TC G + C
Sbjct: 424 SCDAH--------DDSYTCECPRGFH--GKHCEKARPHLCSSGPCRNGGTCKEAGGEYHC 473
Query: 502 LCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGFTRAA 560
C + G C D CA+ P C N G C + G Y+CDC GF+
Sbjct: 474 SCPYRFTGRH-------CEIG--KPDSCASGP--CHNGGTCFHYIGKYKCDCPPGFS--- 519
Query: 561 DGRSC 565
GR C
Sbjct: 520 -GRHC 523
Score = 101 bits (241), Expect = 9e-21
Identities = 108/436 (24%), Positives = 162/436 (37%), Gaps = 65/436 (14%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGY 191
G C G + C C + + D + C G C + S+TC C G+
Sbjct: 387 GYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPC------FNGGSCDAHDDSYTCECPRGF 440
Query: 192 KADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSI 250
K + C+ CR GG C G + C C + D C+
Sbjct: 441 HGKHCEKARPHL--CSSGP--CRNGGTCKEAGGEYHCSCPY--RFTGRHCEIGKPDSCA- 493
Query: 251 TSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SCVNTPGS 307
SG C NG C + +G Y+C C G++ C + +C +
Sbjct: 494 -SGPCHNGGTCFHYIGKYKCDCPPGFS-----GRHCEIAPSPCFRSPCVNGGTCEDRDTD 547
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCR---NTVGSYTC-TCTDGLVPSAA 363
+ C C+ G+ GR C+ +C G R +G+ C G SA
Sbjct: 548 FFCHCQAGYM----GRRCQAEVDC-GPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAP 602
Query: 364 GAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYS 423
CQ ++ + +DE + P L G GSC + + ++C C GY
Sbjct: 603 SRIRVCQPHGVWSEPPQCL---EIDECRSQ-----PCLHG-GSCQDRVAGYLCLCSTGY- 652
Query: 424 VKPEQGPACT-DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLT 481
+G C + DEC C C NLPG++ CRC G+ G CE +VD C
Sbjct: 653 ----EGAHCELERDECRAHPC--RNGGSCRNLPGAYVCRCPAGF--VGVHCETEVDAC-- 702
Query: 482 NNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHC 541
++ C C + G++ C+C + GY TV D C + P G+C
Sbjct: 703 DSSPCQHGGRCESGGGAYLCVCPESF--FGYHCETVS--------DPCFSSP-CGGRGYC 751
Query: 542 SNTPGGYECDCDVGFT 557
+ G + C C VG+T
Sbjct: 752 LASNGSHSCTCKVGYT 767
Score = 91.1 bits (216), Expect = 1e-17
Identities = 113/458 (24%), Positives = 158/458 (34%), Gaps = 56/458 (12%)
Query: 129 CGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHC 187
C HG +C+ G C C GY + +DV++C D G C + G++TC C
Sbjct: 227 CQHGGQCQVENGSAVCVCQAGYTGAACE---MDVDDCS-PDPCLNGGSCVDLVGNYTCLC 282
Query: 188 RPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD--I 245
+K + + + GG CV+ + CEC G L C++
Sbjct: 283 AEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFM----GLDCRERVP 338
Query: 246 DECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTP 305
D+C C NG T C C G+ + C+
Sbjct: 339 DDCE-----CRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHG 393
Query: 306 GSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL-VPSAAG 364
GSY C C + S D D C GG C SYTC C G
Sbjct: 394 GSYLCVCHTDHNASHSLPSPCDSDPC------FNGGSCDAHDDSYTCECPRGFHGKHCEK 447
Query: 365 AKP------TCQDIDECADLISTIIMMSVDELQ-KSVDPQIPELCGAGSCHN------TI 411
A+P C++ C + + + P+ C +G CHN I
Sbjct: 448 ARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYI 507
Query: 412 GSFVCQCPDGYSVKP-EQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
G + C CP G+S + E P+ C G C + F C C+ G+ G
Sbjct: 508 GKYKCDCPPGFSGRHCEIAPSPCFRSPCVNG-------GTCEDRDTDFFCHCQAGYM--G 558
Query: 471 ATCEDVDECLTNNGGCHPRATCANTDGSFRCL--CDTGYKGDGYGLRTVC---CVYS--- 522
C+ +C H T L CD GY VC V+S
Sbjct: 559 RRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPP 618
Query: 523 -CVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRA 559
C++IDEC + P L G C + GY C C G+ A
Sbjct: 619 QCLEIDECRSQPCL-HGGSCQDRVAGYLCLCSTGYEGA 655
Score = 85.0 bits (201), Expect = 6e-16
Identities = 100/408 (24%), Positives = 147/408 (36%), Gaps = 71/408 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTE 180
C + P G G C +TC+C G+ H C G C +G C
Sbjct: 414 CDSDPCFNG-GSCDAHDDSYTCECPRGFHG---KH-CEKARPHLCSSGPCRNGGTCKEAG 468
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
G + C C Y+ D CA GG C + G ++C+C G
Sbjct: 469 GEYHCSCP--YRFTGRHCEIGKPDSCASGPCH-NGGTCFHYIGKYKCDCPPGFS----GR 521
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
C+ S + G CE++ + C C GY ++ + +
Sbjct: 522 HCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFN 581
Query: 301 CVNTPGSYHCTCREGWHLRADGR--------------SCRDIDECAGGARPC-GGGQCRN 345
C G+ L A R C +IDEC ++PC GG C++
Sbjct: 582 GTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECR--SQPCLHGGSCQD 639
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGA 404
V Y C C+ G GA C+ + DEC +
Sbjct: 640 RVAGYLCLCSTGY----EGAH--CELERDEC---------------------RAHPCRNG 672
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCR 463
GSC N G++VC+CP G+ G C T+ D C+ + C C + G++ C C
Sbjct: 673 GSCRNLPGAYVCRCPAGF-----VGVHCETEVDACD--SSPCQHGGRCESGGGAYLCVCP 725
Query: 464 DGWRGDGATCEDV-DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
+ + G CE V D C ++ C R C ++GS C C GY G+
Sbjct: 726 ESF--FGYHCETVSDPCFSS--PCGGRGYCLASNGSHSCTCKVGYTGE 769
Score = 83.4 bits (197), Expect = 2e-15
Identities = 68/253 (26%), Positives = 108/253 (42%), Gaps = 32/253 (12%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNT 179
+ CA+ P G G C + +G + CDC PG+ S H + + C V G G C +
Sbjct: 490 DSCASGPCHNG-GTCFHYIGKYKCDCPPGF---SGRHCEIAPSPCFRSPCVNG-GTCEDR 544
Query: 180 EGSFTCHCRPGYKADDF-SKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
+ F CHC+ GY +++ E + L G + + C+ G+ + AP
Sbjct: 545 DTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLS-APS 603
Query: 239 RL-------------SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXX 285
R+ C +IDEC + G+C++++ Y C+C GY + +
Sbjct: 604 RIRVCQPHGVWSEPPQCLEIDECR-SQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE---L 659
Query: 286 XXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQC 343
R SC N PG+Y C C G+ G C ++D C + PC GG+C
Sbjct: 660 ERDECRAHPCRNGGSCRNLPGAYVCRCPAGF----VGVHCETEVDAC--DSSPCQHGGRC 713
Query: 344 RNTVGSYTCTCTD 356
+ G+Y C C +
Sbjct: 714 ESGGGAYLCVCPE 726
Score = 41.1 bits (92), Expect = 0.010
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 13/87 (14%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDC---FPGYEKDSKNHTCVDVNECEIVDGVC 171
+ EV+ C + P C HG RC + G + C C F GY ++ + C + C
Sbjct: 696 ETEVDACDSSP--CQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFS-SPCG------ 746
Query: 172 GDGDCHNTEGSFTCHCRPGYKADDFSK 198
G G C + GS +C C+ GY +D +K
Sbjct: 747 GRGYCLASNGSHSCTCKVGYTGEDCAK 773
>D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein.
Length = 810
Score = 115 bits (277), Expect = 4e-25
Identities = 83/258 (32%), Positives = 102/258 (39%), Gaps = 25/258 (9%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGY-EKDSKNHTCVDVNECEIVDGVC-GDGDCH 177
N CA P + C+N TC+C GY + C D++EC C + C
Sbjct: 393 NFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCV 452
Query: 178 NTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMEL 235
N G + C C PGY + DDFS C + DEC C C NT C C G
Sbjct: 453 NLPGLYRCDCVPGYIRVDDFS--CTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY-- 508
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ C+ E G G C + +CVC G+ S +
Sbjct: 509 VGNGTICRAFCE----EGCRYGGTC---VAPNKCVCPSGFTGSHCEKDIDECSEGIIECH 561
Query: 296 RCQHS-CVNTPGSYHCTCREGWH----LRADGRSCRDIDECAGGARPC-GGGQCRNTVGS 349
HS CVN PG YHC CR G+H G SC DIDECA C C N G
Sbjct: 562 N--HSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGG 619
Query: 350 YTCTCTDGLVPSAAGAKP 367
+ C C G PS +G P
Sbjct: 620 FDCLCPSG--PSCSGDCP 635
Score = 105 bits (251), Expect = 6e-22
Identities = 67/195 (34%), Positives = 81/195 (41%), Gaps = 30/195 (15%)
Query: 402 CGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC 460
CG S C N C+C GY C D DEC CH C+NLPG ++C
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 461 RCRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC- 518
C G+ R D +C + DEC + C A C NT C C GY G+G R C
Sbjct: 461 DCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCE 520
Query: 519 --CVY--SCV------------------DIDECANDPTLCEN-GHCSNTPGGYECDCDVG 555
C Y +CV DIDEC+ C N C N PG Y C+C G
Sbjct: 521 EGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSG 580
Query: 556 F----TRAADGRSCL 566
F T + G SC+
Sbjct: 581 FHDDGTYSLSGESCI 595
Score = 103 bits (246), Expect = 2e-21
Identities = 104/360 (28%), Positives = 140/360 (38%), Gaps = 44/360 (12%)
Query: 171 CGDG-DCHNTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRC 227
CG+ +C N TC C+ GY S C DIDECA C CVN G +RC
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
+C G + D SC + DEC C N C N + + C C GY +
Sbjct: 461 DCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV-----GNGTI 514
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGG-GQCR 344
R +CV P C C G+ G C +DIDEC+ G C +C
Sbjct: 515 CRAFCEEGCRYGGTCV-APNK--CVCPSGF----TGSHCEKDIDECSEGIIECHNHSRCV 567
Query: 345 NTVGSYTCTCTDGLVPSAAGAKP--TCQDIDECADLISTIIMMSV-DELQKSVDPQIPE- 400
N G Y C C G + +C DIDECA T S L D P
Sbjct: 568 NLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Query: 401 -LCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE---CELGTCDC-HPAADCINLP 455
C +G C + G + +++K ++ C+ D C CDC +P+AD P
Sbjct: 628 PSC-SGDCPHEGG--LKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFCCP 684
Query: 456 G-----SFQCRCRDGWR----GDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCD 504
+ QC ++G + GD T C+ CL C P TC N + + +
Sbjct: 685 ECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQC-RCLEGEVDCWP-LTCPNLSCEYTAILE 742
Score = 99.1 bits (236), Expect = 4e-20
Identities = 70/229 (30%), Positives = 94/229 (41%), Gaps = 31/229 (13%)
Query: 301 CVNTPGSYHCTCREGW-HLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGL 358
C N C C+ G+ ++ D C DIDECA C C N G Y C C G
Sbjct: 407 CKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY 466
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSV--DELQKSVDPQIPELCGAGS-----CHNTI 411
+ + C + DEC ++ + +Q P G G+ C
Sbjct: 467 IRVDDFS---CTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGC 523
Query: 412 ---GSFV----CQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCR 463
G+ V C CP G++ G C D DEC G +CH + C+NLPG + C CR
Sbjct: 524 RYGGTCVAPNKCVCPSGFT-----GSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECR 578
Query: 464 DGWRGDGA------TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
G+ DG +C D+DEC C + C N G F CLC +G
Sbjct: 579 SGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 97.1 bits (231), Expect = 1e-19
Identities = 76/273 (27%), Positives = 101/273 (36%), Gaps = 21/273 (7%)
Query: 213 CRGGRCVN-TAGSFRCECGHGMELAPDRLSCKDI---DECSITSGICSNGACENQMGTYQ 268
CRGG V T C + P+ C+ + C+ N C+N
Sbjct: 356 CRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKAT 415
Query: 269 CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHLRADGRSC 325
C C GY S H+ CVN PG Y C C G+ +R D SC
Sbjct: 416 CECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSC 474
Query: 326 RDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAKPTCQD----IDECADLIS 380
+ DEC G C C NTV ++CTC G V + + C++ C
Sbjct: 475 TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNK 534
Query: 381 TIIM--MSVDELQKSVD---PQIPELCGAGSCHNTIGSFVCQCPDGY---SVKPEQGPAC 432
+ + +K +D I E C N G + C+C G+ G +C
Sbjct: 535 CVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESC 594
Query: 433 TDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
D DEC L T C + CINL G F C C G
Sbjct: 595 IDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 84.6 bits (200), Expect = 8e-16
Identities = 75/263 (28%), Positives = 103/263 (39%), Gaps = 37/263 (14%)
Query: 309 HC--TCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAG-- 364
HC TC+ L D S D D C G +CR D L AG
Sbjct: 268 HCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQC 327
Query: 365 ---AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC----HNTIGSFVCQ 417
+P C + I+ S E + V +I E+C +C H + C+
Sbjct: 328 CKVCRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCR 387
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW---RGDGATCE 474
G++ E GP C ++ EC+ N C C+ G+ +GD A CE
Sbjct: 388 VCRGHNFCAE-GPKCGENSECK-------------NWNTKATCECKSGYISVQGDSAYCE 433
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D+DEC CH C N G +RC C GY +R +SC + DEC +
Sbjct: 434 DIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY------IRV--DDFSCTEHDECGSGQH 485
Query: 535 LC-ENGHCSNTPGGYECDCDVGF 556
C EN C+NT G+ C C G+
Sbjct: 486 NCDENAICTNTVQGHSCTCKPGY 508
>BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 115 bits (277), Expect = 4e-25
Identities = 83/258 (32%), Positives = 102/258 (39%), Gaps = 25/258 (9%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGY-EKDSKNHTCVDVNECEIVDGVC-GDGDCH 177
N CA P + C+N TC+C GY + C D++EC C + C
Sbjct: 393 NFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCV 452
Query: 178 NTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMEL 235
N G + C C PGY + DDFS C + DEC C C NT C C G
Sbjct: 453 NLPGLYRCDCVPGYIRVDDFS--CTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY-- 508
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ C+ E G G C + +CVC G+ S +
Sbjct: 509 VGNGTICRAFCE----EGCRYGGTC---VAPNKCVCPSGFTGSHCEKDIDECSEGIIECH 561
Query: 296 RCQHS-CVNTPGSYHCTCREGWH----LRADGRSCRDIDECAGGARPC-GGGQCRNTVGS 349
HS CVN PG YHC CR G+H G SC DIDECA C C N G
Sbjct: 562 N--HSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGG 619
Query: 350 YTCTCTDGLVPSAAGAKP 367
+ C C G PS +G P
Sbjct: 620 FDCLCPSG--PSCSGDCP 635
Score = 105 bits (251), Expect = 6e-22
Identities = 67/195 (34%), Positives = 81/195 (41%), Gaps = 30/195 (15%)
Query: 402 CGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC 460
CG S C N C+C GY C D DEC CH C+NLPG ++C
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 461 RCRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC- 518
C G+ R D +C + DEC + C A C NT C C GY G+G R C
Sbjct: 461 DCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCE 520
Query: 519 --CVY--SCV------------------DIDECANDPTLCEN-GHCSNTPGGYECDCDVG 555
C Y +CV DIDEC+ C N C N PG Y C+C G
Sbjct: 521 EGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSG 580
Query: 556 F----TRAADGRSCL 566
F T + G SC+
Sbjct: 581 FHDDGTYSLSGESCI 595
Score = 103 bits (246), Expect = 2e-21
Identities = 104/360 (28%), Positives = 140/360 (38%), Gaps = 44/360 (12%)
Query: 171 CGDG-DCHNTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRC 227
CG+ +C N TC C+ GY S C DIDECA C CVN G +RC
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
+C G + D SC + DEC C N C N + + C C GY +
Sbjct: 461 DCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV-----GNGTI 514
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGG-GQCR 344
R +CV P C C G+ G C +DIDEC+ G C +C
Sbjct: 515 CRAFCEEGCRYGGTCV-APNK--CVCPSGF----TGSHCEKDIDECSEGIIECHNHSRCV 567
Query: 345 NTVGSYTCTCTDGLVPSAAGAKP--TCQDIDECADLISTIIMMSV-DELQKSVDPQIPE- 400
N G Y C C G + +C DIDECA T S L D P
Sbjct: 568 NLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Query: 401 -LCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE---CELGTCDC-HPAADCINLP 455
C +G C + G + +++K ++ C+ D C CDC +P+AD P
Sbjct: 628 PSC-SGDCPHEGG--LKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFCCP 684
Query: 456 G-----SFQCRCRDGWR----GDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCD 504
+ QC ++G + GD T C+ CL C P TC N + + +
Sbjct: 685 ECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQC-RCLEGEVDCWP-LTCPNLSCEYTAILE 742
Score = 99.1 bits (236), Expect = 4e-20
Identities = 70/229 (30%), Positives = 94/229 (41%), Gaps = 31/229 (13%)
Query: 301 CVNTPGSYHCTCREGW-HLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGL 358
C N C C+ G+ ++ D C DIDECA C C N G Y C C G
Sbjct: 407 CKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY 466
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSV--DELQKSVDPQIPELCGAGS-----CHNTI 411
+ + C + DEC ++ + +Q P G G+ C
Sbjct: 467 IRVDDFS---CTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGC 523
Query: 412 ---GSFV----CQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCR 463
G+ V C CP G++ G C D DEC G +CH + C+NLPG + C CR
Sbjct: 524 RYGGTCVAPNKCVCPSGFT-----GSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECR 578
Query: 464 DGWRGDGA------TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
G+ DG +C D+DEC C + C N G F CLC +G
Sbjct: 579 SGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 97.1 bits (231), Expect = 1e-19
Identities = 76/273 (27%), Positives = 101/273 (36%), Gaps = 21/273 (7%)
Query: 213 CRGGRCVN-TAGSFRCECGHGMELAPDRLSCKDI---DECSITSGICSNGACENQMGTYQ 268
CRGG V T C + P+ C+ + C+ N C+N
Sbjct: 356 CRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKAT 415
Query: 269 CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHLRADGRSC 325
C C GY S H+ CVN PG Y C C G+ +R D SC
Sbjct: 416 CECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSC 474
Query: 326 RDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAKPTCQD----IDECADLIS 380
+ DEC G C C NTV ++CTC G V + + C++ C
Sbjct: 475 TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNK 534
Query: 381 TIIM--MSVDELQKSVD---PQIPELCGAGSCHNTIGSFVCQCPDGY---SVKPEQGPAC 432
+ + +K +D I E C N G + C+C G+ G +C
Sbjct: 535 CVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESC 594
Query: 433 TDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
D DEC L T C + CINL G F C C G
Sbjct: 595 IDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 84.6 bits (200), Expect = 8e-16
Identities = 75/263 (28%), Positives = 103/263 (39%), Gaps = 37/263 (14%)
Query: 309 HC--TCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAG-- 364
HC TC+ L D S D D C G +CR D L AG
Sbjct: 268 HCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQC 327
Query: 365 ---AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC----HNTIGSFVCQ 417
+P C + I+ S E + V +I E+C +C H + C+
Sbjct: 328 CKVCRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCR 387
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW---RGDGATCE 474
G++ E GP C ++ EC+ N C C+ G+ +GD A CE
Sbjct: 388 VCRGHNFCAE-GPKCGENSECK-------------NWNTKATCECKSGYISVQGDSAYCE 433
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D+DEC CH C N G +RC C GY +R +SC + DEC +
Sbjct: 434 DIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY------IRV--DDFSCTEHDECGSGQH 485
Query: 535 LC-ENGHCSNTPGGYECDCDVGF 556
C EN C+NT G+ C C G+
Sbjct: 486 NCDENAICTNTVQGHSCTCKPGY 508
>BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 115 bits (277), Expect = 4e-25
Identities = 83/258 (32%), Positives = 102/258 (39%), Gaps = 25/258 (9%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGY-EKDSKNHTCVDVNECEIVDGVC-GDGDCH 177
N CA P + C+N TC+C GY + C D++EC C + C
Sbjct: 393 NFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCV 452
Query: 178 NTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMEL 235
N G + C C PGY + DDFS C + DEC C C NT C C G
Sbjct: 453 NLPGLYRCDCVPGYIRVDDFS--CTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY-- 508
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ C+ E G G C + +CVC G+ S +
Sbjct: 509 VGNGTICRAFCE----EGCRYGGTC---VAPNKCVCPSGFTGSHCEKDIDECSEGIIECH 561
Query: 296 RCQHS-CVNTPGSYHCTCREGWH----LRADGRSCRDIDECAGGARPC-GGGQCRNTVGS 349
HS CVN PG YHC CR G+H G SC DIDECA C C N G
Sbjct: 562 N--HSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGG 619
Query: 350 YTCTCTDGLVPSAAGAKP 367
+ C C G PS +G P
Sbjct: 620 FDCLCPSG--PSCSGDCP 635
Score = 105 bits (251), Expect = 6e-22
Identities = 67/195 (34%), Positives = 81/195 (41%), Gaps = 30/195 (15%)
Query: 402 CGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC 460
CG S C N C+C GY C D DEC CH C+NLPG ++C
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 461 RCRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC- 518
C G+ R D +C + DEC + C A C NT C C GY G+G R C
Sbjct: 461 DCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCE 520
Query: 519 --CVY--SCV------------------DIDECANDPTLCEN-GHCSNTPGGYECDCDVG 555
C Y +CV DIDEC+ C N C N PG Y C+C G
Sbjct: 521 EGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSG 580
Query: 556 F----TRAADGRSCL 566
F T + G SC+
Sbjct: 581 FHDDGTYSLSGESCI 595
Score = 103 bits (246), Expect = 2e-21
Identities = 104/360 (28%), Positives = 140/360 (38%), Gaps = 44/360 (12%)
Query: 171 CGDG-DCHNTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRC 227
CG+ +C N TC C+ GY S C DIDECA C CVN G +RC
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
+C G + D SC + DEC C N C N + + C C GY +
Sbjct: 461 DCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV-----GNGTI 514
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGG-GQCR 344
R +CV P C C G+ G C +DIDEC+ G C +C
Sbjct: 515 CRAFCEEGCRYGGTCV-APNK--CVCPSGF----TGSHCEKDIDECSEGIIECHNHSRCV 567
Query: 345 NTVGSYTCTCTDGLVPSAAGAKP--TCQDIDECADLISTIIMMSV-DELQKSVDPQIPE- 400
N G Y C C G + +C DIDECA T S L D P
Sbjct: 568 NLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Query: 401 -LCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE---CELGTCDC-HPAADCINLP 455
C +G C + G + +++K ++ C+ D C CDC +P+AD P
Sbjct: 628 PSC-SGDCPHEGG--LKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFCCP 684
Query: 456 G-----SFQCRCRDGWR----GDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCD 504
+ QC ++G + GD T C+ CL C P TC N + + +
Sbjct: 685 ECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQC-RCLEGEVDCWP-LTCPNLSCEYTAILE 742
Score = 99.1 bits (236), Expect = 4e-20
Identities = 70/229 (30%), Positives = 94/229 (41%), Gaps = 31/229 (13%)
Query: 301 CVNTPGSYHCTCREGW-HLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGL 358
C N C C+ G+ ++ D C DIDECA C C N G Y C C G
Sbjct: 407 CKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY 466
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSV--DELQKSVDPQIPELCGAGS-----CHNTI 411
+ + C + DEC ++ + +Q P G G+ C
Sbjct: 467 IRVDDFS---CTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGC 523
Query: 412 ---GSFV----CQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCR 463
G+ V C CP G++ G C D DEC G +CH + C+NLPG + C CR
Sbjct: 524 RYGGTCVAPNKCVCPSGFT-----GSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECR 578
Query: 464 DGWRGDGA------TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
G+ DG +C D+DEC C + C N G F CLC +G
Sbjct: 579 SGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 97.1 bits (231), Expect = 1e-19
Identities = 76/273 (27%), Positives = 101/273 (36%), Gaps = 21/273 (7%)
Query: 213 CRGGRCVN-TAGSFRCECGHGMELAPDRLSCKDI---DECSITSGICSNGACENQMGTYQ 268
CRGG V T C + P+ C+ + C+ N C+N
Sbjct: 356 CRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKAT 415
Query: 269 CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHLRADGRSC 325
C C GY S H+ CVN PG Y C C G+ +R D SC
Sbjct: 416 CECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSC 474
Query: 326 RDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAKPTCQD----IDECADLIS 380
+ DEC G C C NTV ++CTC G V + + C++ C
Sbjct: 475 TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNK 534
Query: 381 TIIM--MSVDELQKSVD---PQIPELCGAGSCHNTIGSFVCQCPDGY---SVKPEQGPAC 432
+ + +K +D I E C N G + C+C G+ G +C
Sbjct: 535 CVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESC 594
Query: 433 TDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
D DEC L T C + CINL G F C C G
Sbjct: 595 IDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 84.6 bits (200), Expect = 8e-16
Identities = 75/263 (28%), Positives = 103/263 (39%), Gaps = 37/263 (14%)
Query: 309 HC--TCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAG-- 364
HC TC+ L D S D D C G +CR D L AG
Sbjct: 268 HCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQC 327
Query: 365 ---AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC----HNTIGSFVCQ 417
+P C + I+ S E + V +I E+C +C H + C+
Sbjct: 328 CKVCRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCR 387
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW---RGDGATCE 474
G++ E GP C ++ EC+ N C C+ G+ +GD A CE
Sbjct: 388 VCRGHNFCAE-GPKCGENSECK-------------NWNTKATCECKSGYISVQGDSAYCE 433
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D+DEC CH C N G +RC C GY +R +SC + DEC +
Sbjct: 434 DIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY------IRV--DDFSCTEHDECGSGQH 485
Query: 535 LC-ENGHCSNTPGGYECDCDVGF 556
C EN C+NT G+ C C G+
Sbjct: 486 NCDENAICTNTVQGHSCTCKPGY 508
>BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor
protein.
Length = 810
Score = 115 bits (277), Expect = 4e-25
Identities = 83/258 (32%), Positives = 102/258 (39%), Gaps = 25/258 (9%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGY-EKDSKNHTCVDVNECEIVDGVC-GDGDCH 177
N CA P + C+N TC+C GY + C D++EC C + C
Sbjct: 393 NFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCV 452
Query: 178 NTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMEL 235
N G + C C PGY + DDFS C + DEC C C NT C C G
Sbjct: 453 NLPGLYRCDCVPGYIRVDDFS--CTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY-- 508
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
+ C+ E G G C + +CVC G+ S +
Sbjct: 509 VGNGTICRAFCE----EGCRYGGTC---VAPNKCVCPSGFTGSHCEKDIDECSEGIIECH 561
Query: 296 RCQHS-CVNTPGSYHCTCREGWH----LRADGRSCRDIDECAGGARPC-GGGQCRNTVGS 349
HS CVN PG YHC CR G+H G SC DIDECA C C N G
Sbjct: 562 N--HSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGG 619
Query: 350 YTCTCTDGLVPSAAGAKP 367
+ C C G PS +G P
Sbjct: 620 FDCLCPSG--PSCSGDCP 635
Score = 105 bits (251), Expect = 6e-22
Identities = 67/195 (34%), Positives = 81/195 (41%), Gaps = 30/195 (15%)
Query: 402 CGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC 460
CG S C N C+C GY C D DEC CH C+NLPG ++C
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 461 RCRDGW-RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC- 518
C G+ R D +C + DEC + C A C NT C C GY G+G R C
Sbjct: 461 DCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCE 520
Query: 519 --CVY--SCV------------------DIDECANDPTLCEN-GHCSNTPGGYECDCDVG 555
C Y +CV DIDEC+ C N C N PG Y C+C G
Sbjct: 521 EGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSG 580
Query: 556 F----TRAADGRSCL 566
F T + G SC+
Sbjct: 581 FHDDGTYSLSGESCI 595
Score = 103 bits (246), Expect = 2e-21
Identities = 104/360 (28%), Positives = 140/360 (38%), Gaps = 44/360 (12%)
Query: 171 CGDG-DCHNTEGSFTCHCRPGY-KADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRC 227
CG+ +C N TC C+ GY S C DIDECA C CVN G +RC
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXX 286
+C G + D SC + DEC C N C N + + C C GY +
Sbjct: 461 DCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV-----GNGTI 514
Query: 287 XXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGG-GQCR 344
R +CV P C C G+ G C +DIDEC+ G C +C
Sbjct: 515 CRAFCEEGCRYGGTCV-APNK--CVCPSGF----TGSHCEKDIDECSEGIIECHNHSRCV 567
Query: 345 NTVGSYTCTCTDGLVPSAAGAKP--TCQDIDECADLISTIIMMSV-DELQKSVDPQIPE- 400
N G Y C C G + +C DIDECA T S L D P
Sbjct: 568 NLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Query: 401 -LCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE---CELGTCDC-HPAADCINLP 455
C +G C + G + +++K ++ C+ D C CDC +P+AD P
Sbjct: 628 PSC-SGDCPHEGG--LKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFCCP 684
Query: 456 G-----SFQCRCRDGWR----GDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCD 504
+ QC ++G + GD T C+ CL C P TC N + + +
Sbjct: 685 ECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQC-RCLEGEVDCWP-LTCPNLSCEYTAILE 742
Score = 99.1 bits (236), Expect = 4e-20
Identities = 70/229 (30%), Positives = 94/229 (41%), Gaps = 31/229 (13%)
Query: 301 CVNTPGSYHCTCREGW-HLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGL 358
C N C C+ G+ ++ D C DIDECA C C N G Y C C G
Sbjct: 407 CKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY 466
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSV--DELQKSVDPQIPELCGAGS-----CHNTI 411
+ + C + DEC ++ + +Q P G G+ C
Sbjct: 467 IRVDDFS---CTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGC 523
Query: 412 ---GSFV----CQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRCR 463
G+ V C CP G++ G C D DEC G +CH + C+NLPG + C CR
Sbjct: 524 RYGGTCVAPNKCVCPSGFT-----GSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECR 578
Query: 464 DGWRGDGA------TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
G+ DG +C D+DEC C + C N G F CLC +G
Sbjct: 579 SGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 97.1 bits (231), Expect = 1e-19
Identities = 76/273 (27%), Positives = 101/273 (36%), Gaps = 21/273 (7%)
Query: 213 CRGGRCVN-TAGSFRCECGHGMELAPDRLSCKDI---DECSITSGICSNGACENQMGTYQ 268
CRGG V T C + P+ C+ + C+ N C+N
Sbjct: 356 CRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKAT 415
Query: 269 CVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS---CVNTPGSYHCTCREGWHLRADGRSC 325
C C GY S H+ CVN PG Y C C G+ +R D SC
Sbjct: 416 CECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSC 474
Query: 326 RDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAKPTCQD----IDECADLIS 380
+ DEC G C C NTV ++CTC G V + + C++ C
Sbjct: 475 TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNK 534
Query: 381 TIIM--MSVDELQKSVD---PQIPELCGAGSCHNTIGSFVCQCPDGY---SVKPEQGPAC 432
+ + +K +D I E C N G + C+C G+ G +C
Sbjct: 535 CVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESC 594
Query: 433 TDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
D DEC L T C + CINL G F C C G
Sbjct: 595 IDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 84.6 bits (200), Expect = 8e-16
Identities = 75/263 (28%), Positives = 103/263 (39%), Gaps = 37/263 (14%)
Query: 309 HC--TCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAG-- 364
HC TC+ L D S D D C G +CR D L AG
Sbjct: 268 HCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQC 327
Query: 365 ---AKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC----HNTIGSFVCQ 417
+P C + I+ S E + V +I E+C +C H + C+
Sbjct: 328 CKVCRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCR 387
Query: 418 CPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW---RGDGATCE 474
G++ E GP C ++ EC+ N C C+ G+ +GD A CE
Sbjct: 388 VCRGHNFCAE-GPKCGENSECK-------------NWNTKATCECKSGYISVQGDSAYCE 433
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D+DEC CH C N G +RC C GY +R +SC + DEC +
Sbjct: 434 DIDECAAKMHYCHANTVCVNLPGLYRCDCVPGY------IRV--DDFSCTEHDECGSGQH 485
Query: 535 LC-ENGHCSNTPGGYECDCDVGF 556
C EN C+NT G+ C C G+
Sbjct: 486 NCDENAICTNTVQGHSCTCKPGY 508
>Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein.
Length = 676
Score = 114 bits (275), Expect = 7e-25
Identities = 57/160 (35%), Positives = 82/160 (51%), Gaps = 9/160 (5%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR--CVNTAGSFRCECGHGM 233
C + + SFTC C+PG++ + K DI+EC D + G C NT GS+ C C +G
Sbjct: 134 CKDGKASFTCTCKPGWQGE---KCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
+ ++ CKD+DECS+ IC C+N G ++C C EGY + +KS
Sbjct: 191 VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY-RYNLKS-KSCEDIDECS 248
Query: 294 XXRCQHSCVNTPGSYHCTC--REGWHLRADGRSCRDIDEC 331
C CVN PG Y C C ++G+ L D +SC + C
Sbjct: 249 ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 104 bits (249), Expect = 1e-21
Identities = 54/156 (34%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 120 NECAAFP-GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD--C 176
++C+ P G+ C++ FTC C PG++ + D+NEC+ + G C
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEF---DINECKDPSNINGGCSQIC 175
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS+ C C+ G+ K C D+DEC+ ++C C N G F CEC G
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 235
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
SC+DIDECS +C+ C N G Y C CD
Sbjct: 236 LKSKSCEDIDECS--ENMCAQ-LCVNYPGGYTCYCD 268
Score = 101 bits (241), Expect = 9e-21
Identities = 68/192 (35%), Positives = 88/192 (45%), Gaps = 40/192 (20%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQ--CRNTVGSYTCTCTD 356
SC + S+ CTC+ GW G C DI+EC + GG C NT GSY C+C +
Sbjct: 133 SCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 188
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G V K C+D+DEC+ L+ P +CG C N G F C
Sbjct: 189 GFV--MLSNKKDCKDVDECS-------------LK-------PSICGTAVCKNIPGDFEC 226
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGA 471
+CP+GY + +C D DEC C A C+N PG + C C DG +G D
Sbjct: 227 ECPEGYRYN-LKSKSCEDIDECSENMC----AQLCVNYPGGYTCYC-DGKKGFKLAQDQK 280
Query: 472 TCEDVDECLTNN 483
+CE V CL N
Sbjct: 281 SCEVVSVCLPLN 292
Score = 96.7 bits (230), Expect = 2e-19
Identities = 50/138 (36%), Positives = 69/138 (50%), Gaps = 9/138 (6%)
Query: 116 QMEVNEC---AAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
+ ++NEC + G C C N G + C C G+ S C DV+EC + +CG
Sbjct: 155 EFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG 213
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECG-- 230
C N G F C C GY+ + SK C DIDEC++N +C CVN G + C C
Sbjct: 214 TAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MC-AQLCVNYPGGYTCYCDGK 270
Query: 231 HGMELAPDRLSCKDIDEC 248
G +LA D+ SC+ + C
Sbjct: 271 KGFKLAQDQKSCEVVSVC 288
Score = 94.7 bits (225), Expect = 8e-19
Identities = 63/169 (37%), Positives = 82/169 (48%), Gaps = 22/169 (13%)
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DEC-ELGTCDCHPAADCINLPGSFQC 460
G SC + SF C C G+ QG C D +EC + + + C N PGS+ C
Sbjct: 130 GYMSCKDGKASFTCTCKPGW-----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHC 184
Query: 461 RCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C++G+ + C+DVDEC C A C N G F C C GY+ Y L++
Sbjct: 185 SCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPGDFECECPEGYR---YNLKSK- 239
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD--VGFTRAADGRSC 565
SC DIDEC+ + +C C N PGGY C CD GF A D +SC
Sbjct: 240 ---SCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 89.8 bits (213), Expect = 2e-17
Identities = 42/144 (29%), Positives = 70/144 (48%), Gaps = 5/144 (3%)
Query: 237 PDRLSCKDI--DECS-ITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
PD SC + D+CS + +C++ ++ C C G+ +
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNI 167
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C C NTPGSYHC+C+ G+ + ++ + C+D+DEC+ CG C+N G + C
Sbjct: 168 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
Query: 354 CTDGLVPSAAGAKPTCQDIDECAD 377
C +G + +C+DIDEC++
Sbjct: 228 CPEGYRYNL--KSKSCEDIDECSE 249
Score = 86.6 bits (205), Expect = 2e-16
Identities = 46/134 (34%), Positives = 66/134 (49%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECL--TN-NGGCHPRAT 491
D+C C+ C + SF C C+ GW+G+ CE D++EC +N NGGC
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGGCSQ--I 174
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
C NT GS+ C C G+ + C D+DEC+ P++C C N PG +EC+
Sbjct: 175 CDNTPGSYHCSCKNGFV-------MLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
Query: 552 CDVGFTRAADGRSC 565
C G+ +SC
Sbjct: 228 CPEGYRYNLKSKSC 241
Score = 78.2 bits (184), Expect = 7e-14
Identities = 46/162 (28%), Positives = 64/162 (39%), Gaps = 5/162 (3%)
Query: 218 CVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ 277
C + SF C C G + + + S +G CS C+N G+Y C C G+
Sbjct: 134 CKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVM 192
Query: 278 STVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGAR 336
+ K C + C N PG + C C EG+ +SC DIDEC+
Sbjct: 193 LSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENM- 251
Query: 337 PCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
C C N G YTC C A + +C+ + C L
Sbjct: 252 -CAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPL 291
>M57853-1|AAA60357.1| 676|Homo sapiens S protein protein.
Length = 676
Score = 114 bits (275), Expect = 7e-25
Identities = 57/160 (35%), Positives = 82/160 (51%), Gaps = 9/160 (5%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR--CVNTAGSFRCECGHGM 233
C + + SFTC C+PG++ + K DI+EC D + G C NT GS+ C C +G
Sbjct: 134 CKDGKASFTCTCKPGWQGE---KCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
+ ++ CKD+DECS+ IC C+N G ++C C EGY + +KS
Sbjct: 191 VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY-RYNLKS-KSCEDIDECS 248
Query: 294 XXRCQHSCVNTPGSYHCTC--REGWHLRADGRSCRDIDEC 331
C CVN PG Y C C ++G+ L D +SC + C
Sbjct: 249 ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 104 bits (249), Expect = 1e-21
Identities = 54/156 (34%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 120 NECAAFP-GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD--C 176
++C+ P G+ C++ FTC C PG++ + D+NEC+ + G C
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEF---DINECKDPSNINGGCSQIC 175
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS+ C C+ G+ K C D+DEC+ ++C C N G F CEC G
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 235
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
SC+DIDECS +C+ C N G Y C CD
Sbjct: 236 LKSKSCEDIDECS--ENMCAQ-LCVNYPGGYTCYCD 268
Score = 101 bits (241), Expect = 9e-21
Identities = 68/192 (35%), Positives = 88/192 (45%), Gaps = 40/192 (20%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQ--CRNTVGSYTCTCTD 356
SC + S+ CTC+ GW G C DI+EC + GG C NT GSY C+C +
Sbjct: 133 SCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 188
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G V K C+D+DEC+ L+ P +CG C N G F C
Sbjct: 189 GFV--MLSNKKDCKDVDECS-------------LK-------PSICGTAVCKNIPGDFEC 226
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGA 471
+CP+GY + +C D DEC C A C+N PG + C C DG +G D
Sbjct: 227 ECPEGYRYN-LKSKSCEDIDECSENMC----AQLCVNYPGGYTCYC-DGKKGFKLAQDQK 280
Query: 472 TCEDVDECLTNN 483
+CE V CL N
Sbjct: 281 SCEVVSVCLPLN 292
Score = 96.7 bits (230), Expect = 2e-19
Identities = 50/138 (36%), Positives = 69/138 (50%), Gaps = 9/138 (6%)
Query: 116 QMEVNEC---AAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
+ ++NEC + G C C N G + C C G+ S C DV+EC + +CG
Sbjct: 155 EFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG 213
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECG-- 230
C N G F C C GY+ + SK C DIDEC++N +C CVN G + C C
Sbjct: 214 TAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MC-AQLCVNYPGGYTCYCDGK 270
Query: 231 HGMELAPDRLSCKDIDEC 248
G +LA D+ SC+ + C
Sbjct: 271 KGFKLAQDQKSCEVVSVC 288
Score = 94.7 bits (225), Expect = 8e-19
Identities = 63/169 (37%), Positives = 82/169 (48%), Gaps = 22/169 (13%)
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DEC-ELGTCDCHPAADCINLPGSFQC 460
G SC + SF C C G+ QG C D +EC + + + C N PGS+ C
Sbjct: 130 GYMSCKDGKASFTCTCKPGW-----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHC 184
Query: 461 RCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C++G+ + C+DVDEC C A C N G F C C GY+ Y L++
Sbjct: 185 SCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPGDFECECPEGYR---YNLKSK- 239
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD--VGFTRAADGRSC 565
SC DIDEC+ + +C C N PGGY C CD GF A D +SC
Sbjct: 240 ---SCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 89.8 bits (213), Expect = 2e-17
Identities = 42/144 (29%), Positives = 70/144 (48%), Gaps = 5/144 (3%)
Query: 237 PDRLSCKDI--DECS-ITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
PD SC + D+CS + +C++ ++ C C G+ +
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNI 167
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C C NTPGSYHC+C+ G+ + ++ + C+D+DEC+ CG C+N G + C
Sbjct: 168 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
Query: 354 CTDGLVPSAAGAKPTCQDIDECAD 377
C +G + +C+DIDEC++
Sbjct: 228 CPEGYRYNL--KSKSCEDIDECSE 249
Score = 86.6 bits (205), Expect = 2e-16
Identities = 46/134 (34%), Positives = 66/134 (49%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECL--TN-NGGCHPRAT 491
D+C C+ C + SF C C+ GW+G+ CE D++EC +N NGGC
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGGCSQ--I 174
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
C NT GS+ C C G+ + C D+DEC+ P++C C N PG +EC+
Sbjct: 175 CDNTPGSYHCSCKNGFV-------MLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
Query: 552 CDVGFTRAADGRSC 565
C G+ +SC
Sbjct: 228 CPEGYRYNLKSKSC 241
Score = 78.2 bits (184), Expect = 7e-14
Identities = 46/162 (28%), Positives = 64/162 (39%), Gaps = 5/162 (3%)
Query: 218 CVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ 277
C + SF C C G + + + S +G CS C+N G+Y C C G+
Sbjct: 134 CKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVM 192
Query: 278 STVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGAR 336
+ K C + C N PG + C C EG+ +SC DIDEC+
Sbjct: 193 LSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENM- 251
Query: 337 PCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
C C N G YTC C A + +C+ + C L
Sbjct: 252 -CAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPL 291
>M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein.
Length = 650
Score = 114 bits (275), Expect = 7e-25
Identities = 57/160 (35%), Positives = 82/160 (51%), Gaps = 9/160 (5%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR--CVNTAGSFRCECGHGM 233
C + + SFTC C+PG++ + K DI+EC D + G C NT GS+ C C +G
Sbjct: 108 CKDGKASFTCTCKPGWQGE---KCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 164
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
+ ++ CKD+DECS+ IC C+N G ++C C EGY + +KS
Sbjct: 165 VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY-RYNLKS-KSCEDIDECS 222
Query: 294 XXRCQHSCVNTPGSYHCTC--REGWHLRADGRSCRDIDEC 331
C CVN PG Y C C ++G+ L D +SC + C
Sbjct: 223 ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 262
Score = 104 bits (249), Expect = 1e-21
Identities = 54/156 (34%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 120 NECAAFP-GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD--C 176
++C+ P G+ C++ FTC C PG++ + D+NEC+ + G C
Sbjct: 93 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEF---DINECKDPSNINGGCSQIC 149
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS+ C C+ G+ K C D+DEC+ ++C C N G F CEC G
Sbjct: 150 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 209
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
SC+DIDECS +C+ C N G Y C CD
Sbjct: 210 LKSKSCEDIDECS--ENMCAQ-LCVNYPGGYTCYCD 242
Score = 101 bits (241), Expect = 9e-21
Identities = 68/192 (35%), Positives = 88/192 (45%), Gaps = 40/192 (20%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQ--CRNTVGSYTCTCTD 356
SC + S+ CTC+ GW G C DI+EC + GG C NT GSY C+C +
Sbjct: 107 SCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 162
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G V K C+D+DEC+ L+ P +CG C N G F C
Sbjct: 163 GFV--MLSNKKDCKDVDECS-------------LK-------PSICGTAVCKNIPGDFEC 200
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGA 471
+CP+GY + +C D DEC C A C+N PG + C C DG +G D
Sbjct: 201 ECPEGYRYN-LKSKSCEDIDECSENMC----AQLCVNYPGGYTCYC-DGKKGFKLAQDQK 254
Query: 472 TCEDVDECLTNN 483
+CE V CL N
Sbjct: 255 SCEVVSVCLPLN 266
Score = 96.7 bits (230), Expect = 2e-19
Identities = 50/138 (36%), Positives = 69/138 (50%), Gaps = 9/138 (6%)
Query: 116 QMEVNEC---AAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
+ ++NEC + G C C N G + C C G+ S C DV+EC + +CG
Sbjct: 129 EFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG 187
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECG-- 230
C N G F C C GY+ + SK C DIDEC++N +C CVN G + C C
Sbjct: 188 TAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MC-AQLCVNYPGGYTCYCDGK 244
Query: 231 HGMELAPDRLSCKDIDEC 248
G +LA D+ SC+ + C
Sbjct: 245 KGFKLAQDQKSCEVVSVC 262
Score = 94.7 bits (225), Expect = 8e-19
Identities = 63/169 (37%), Positives = 82/169 (48%), Gaps = 22/169 (13%)
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DEC-ELGTCDCHPAADCINLPGSFQC 460
G SC + SF C C G+ QG C D +EC + + + C N PGS+ C
Sbjct: 104 GYMSCKDGKASFTCTCKPGW-----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHC 158
Query: 461 RCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C++G+ + C+DVDEC C A C N G F C C GY+ Y L++
Sbjct: 159 SCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPGDFECECPEGYR---YNLKSK- 213
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD--VGFTRAADGRSC 565
SC DIDEC+ + +C C N PGGY C CD GF A D +SC
Sbjct: 214 ---SCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 256
Score = 89.8 bits (213), Expect = 2e-17
Identities = 42/144 (29%), Positives = 70/144 (48%), Gaps = 5/144 (3%)
Query: 237 PDRLSCKDI--DECS-ITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
PD SC + D+CS + +C++ ++ C C G+ +
Sbjct: 82 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNI 141
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C C NTPGSYHC+C+ G+ + ++ + C+D+DEC+ CG C+N G + C
Sbjct: 142 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 201
Query: 354 CTDGLVPSAAGAKPTCQDIDECAD 377
C +G + +C+DIDEC++
Sbjct: 202 CPEGYRYNL--KSKSCEDIDECSE 223
Score = 86.6 bits (205), Expect = 2e-16
Identities = 46/134 (34%), Positives = 66/134 (49%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECL--TN-NGGCHPRAT 491
D+C C+ C + SF C C+ GW+G+ CE D++EC +N NGGC
Sbjct: 93 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGGCSQ--I 148
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
C NT GS+ C C G+ + C D+DEC+ P++C C N PG +EC+
Sbjct: 149 CDNTPGSYHCSCKNGFV-------MLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 201
Query: 552 CDVGFTRAADGRSC 565
C G+ +SC
Sbjct: 202 CPEGYRYNLKSKSC 215
Score = 78.2 bits (184), Expect = 7e-14
Identities = 46/162 (28%), Positives = 64/162 (39%), Gaps = 5/162 (3%)
Query: 218 CVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ 277
C + SF C C G + + + S +G CS C+N G+Y C C G+
Sbjct: 108 CKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVM 166
Query: 278 STVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGAR 336
+ K C + C N PG + C C EG+ +SC DIDEC+
Sbjct: 167 LSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENM- 225
Query: 337 PCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
C C N G YTC C A + +C+ + C L
Sbjct: 226 -CAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPL 265
>M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin
K-dependent plasma protein S mRNA, complete cds. ).
Length = 676
Score = 114 bits (275), Expect = 7e-25
Identities = 57/160 (35%), Positives = 82/160 (51%), Gaps = 9/160 (5%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR--CVNTAGSFRCECGHGM 233
C + + SFTC C+PG++ + K DI+EC D + G C NT GS+ C C +G
Sbjct: 134 CKDGKASFTCTCKPGWQGE---KCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
+ ++ CKD+DECS+ IC C+N G ++C C EGY + +KS
Sbjct: 191 VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY-RYNLKS-KSCEDIDECS 248
Query: 294 XXRCQHSCVNTPGSYHCTC--REGWHLRADGRSCRDIDEC 331
C CVN PG Y C C ++G+ L D +SC + C
Sbjct: 249 ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 104 bits (249), Expect = 1e-21
Identities = 54/156 (34%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 120 NECAAFP-GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD--C 176
++C+ P G+ C++ FTC C PG++ + D+NEC+ + G C
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEF---DINECKDPSNINGGCSQIC 175
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS+ C C+ G+ K C D+DEC+ ++C C N G F CEC G
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 235
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
SC+DIDECS +C+ C N G Y C CD
Sbjct: 236 LKSKSCEDIDECS--ENMCAQ-LCVNYPGGYTCYCD 268
Score = 101 bits (241), Expect = 9e-21
Identities = 68/192 (35%), Positives = 88/192 (45%), Gaps = 40/192 (20%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQ--CRNTVGSYTCTCTD 356
SC + S+ CTC+ GW G C DI+EC + GG C NT GSY C+C +
Sbjct: 133 SCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 188
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G V K C+D+DEC+ L+ P +CG C N G F C
Sbjct: 189 GFV--MLSNKKDCKDVDECS-------------LK-------PSICGTAVCKNIPGDFEC 226
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGA 471
+CP+GY + +C D DEC C A C+N PG + C C DG +G D
Sbjct: 227 ECPEGYRYN-LKSKSCEDIDECSENMC----AQLCVNYPGGYTCYC-DGKKGFKLAQDQK 280
Query: 472 TCEDVDECLTNN 483
+CE V CL N
Sbjct: 281 SCEVVSVCLPLN 292
Score = 96.7 bits (230), Expect = 2e-19
Identities = 50/138 (36%), Positives = 69/138 (50%), Gaps = 9/138 (6%)
Query: 116 QMEVNEC---AAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
+ ++NEC + G C C N G + C C G+ S C DV+EC + +CG
Sbjct: 155 EFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG 213
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECG-- 230
C N G F C C GY+ + SK C DIDEC++N +C CVN G + C C
Sbjct: 214 TAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MC-AQLCVNYPGGYTCYCDGK 270
Query: 231 HGMELAPDRLSCKDIDEC 248
G +LA D+ SC+ + C
Sbjct: 271 KGFKLAQDQKSCEVVSVC 288
Score = 94.7 bits (225), Expect = 8e-19
Identities = 63/169 (37%), Positives = 82/169 (48%), Gaps = 22/169 (13%)
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DEC-ELGTCDCHPAADCINLPGSFQC 460
G SC + SF C C G+ QG C D +EC + + + C N PGS+ C
Sbjct: 130 GYMSCKDGKASFTCTCKPGW-----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHC 184
Query: 461 RCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C++G+ + C+DVDEC C A C N G F C C GY+ Y L++
Sbjct: 185 SCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPGDFECECPEGYR---YNLKSK- 239
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD--VGFTRAADGRSC 565
SC DIDEC+ + +C C N PGGY C CD GF A D +SC
Sbjct: 240 ---SCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 89.8 bits (213), Expect = 2e-17
Identities = 42/144 (29%), Positives = 70/144 (48%), Gaps = 5/144 (3%)
Query: 237 PDRLSCKDI--DECS-ITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
PD SC + D+CS + +C++ ++ C C G+ +
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNI 167
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C C NTPGSYHC+C+ G+ + ++ + C+D+DEC+ CG C+N G + C
Sbjct: 168 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
Query: 354 CTDGLVPSAAGAKPTCQDIDECAD 377
C +G + +C+DIDEC++
Sbjct: 228 CPEGYRYNL--KSKSCEDIDECSE 249
Score = 86.6 bits (205), Expect = 2e-16
Identities = 46/134 (34%), Positives = 66/134 (49%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECL--TN-NGGCHPRAT 491
D+C C+ C + SF C C+ GW+G+ CE D++EC +N NGGC
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGGCSQ--I 174
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
C NT GS+ C C G+ + C D+DEC+ P++C C N PG +EC+
Sbjct: 175 CDNTPGSYHCSCKNGFV-------MLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
Query: 552 CDVGFTRAADGRSC 565
C G+ +SC
Sbjct: 228 CPEGYRYNLKSKSC 241
Score = 78.2 bits (184), Expect = 7e-14
Identities = 46/162 (28%), Positives = 64/162 (39%), Gaps = 5/162 (3%)
Query: 218 CVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ 277
C + SF C C G + + + S +G CS C+N G+Y C C G+
Sbjct: 134 CKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVM 192
Query: 278 STVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGAR 336
+ K C + C N PG + C C EG+ +SC DIDEC+
Sbjct: 193 LSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENM- 251
Query: 337 PCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
C C N G YTC C A + +C+ + C L
Sbjct: 252 -CAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPL 291
>BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein.
Length = 676
Score = 114 bits (275), Expect = 7e-25
Identities = 57/160 (35%), Positives = 82/160 (51%), Gaps = 9/160 (5%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR--CVNTAGSFRCECGHGM 233
C + + SFTC C+PG++ + K DI+EC D + G C NT GS+ C C +G
Sbjct: 134 CKDGKASFTCTCKPGWQGE---KCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
+ ++ CKD+DECS+ IC C+N G ++C C EGY + +KS
Sbjct: 191 VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY-RYNLKS-KSCEDIDECS 248
Query: 294 XXRCQHSCVNTPGSYHCTC--REGWHLRADGRSCRDIDEC 331
C CVN PG Y C C ++G+ L D +SC + C
Sbjct: 249 ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 104 bits (249), Expect = 1e-21
Identities = 54/156 (34%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 120 NECAAFP-GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD--C 176
++C+ P G+ C++ FTC C PG++ + D+NEC+ + G C
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEF---DINECKDPSNINGGCSQIC 175
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS+ C C+ G+ K C D+DEC+ ++C C N G F CEC G
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 235
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
SC+DIDECS +C+ C N G Y C CD
Sbjct: 236 LKSKSCEDIDECS--ENMCAQ-LCVNYPGGYTCYCD 268
Score = 101 bits (241), Expect = 9e-21
Identities = 68/192 (35%), Positives = 88/192 (45%), Gaps = 40/192 (20%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQ--CRNTVGSYTCTCTD 356
SC + S+ CTC+ GW G C DI+EC + GG C NT GSY C+C +
Sbjct: 133 SCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 188
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G V K C+D+DEC+ L+ P +CG C N G F C
Sbjct: 189 GFV--MLSNKKDCKDVDECS-------------LK-------PSICGTAVCKNIPGDFEC 226
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGA 471
+CP+GY + +C D DEC C A C+N PG + C C DG +G D
Sbjct: 227 ECPEGYRYN-LKSKSCEDIDECSENMC----AQLCVNYPGGYTCYC-DGKKGFKLAQDQK 280
Query: 472 TCEDVDECLTNN 483
+CE V CL N
Sbjct: 281 SCEVVSVCLPLN 292
Score = 96.7 bits (230), Expect = 2e-19
Identities = 50/138 (36%), Positives = 69/138 (50%), Gaps = 9/138 (6%)
Query: 116 QMEVNEC---AAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
+ ++NEC + G C C N G + C C G+ S C DV+EC + +CG
Sbjct: 155 EFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG 213
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECG-- 230
C N G F C C GY+ + SK C DIDEC++N +C CVN G + C C
Sbjct: 214 TAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MC-AQLCVNYPGGYTCYCDGK 270
Query: 231 HGMELAPDRLSCKDIDEC 248
G +LA D+ SC+ + C
Sbjct: 271 KGFKLAQDQKSCEVVSVC 288
Score = 94.7 bits (225), Expect = 8e-19
Identities = 63/169 (37%), Positives = 82/169 (48%), Gaps = 22/169 (13%)
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DEC-ELGTCDCHPAADCINLPGSFQC 460
G SC + SF C C G+ QG C D +EC + + + C N PGS+ C
Sbjct: 130 GYMSCKDGKASFTCTCKPGW-----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHC 184
Query: 461 RCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C++G+ + C+DVDEC C A C N G F C C GY+ Y L++
Sbjct: 185 SCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPGDFECECPEGYR---YNLKSK- 239
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD--VGFTRAADGRSC 565
SC DIDEC+ + +C C N PGGY C CD GF A D +SC
Sbjct: 240 ---SCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 89.8 bits (213), Expect = 2e-17
Identities = 42/144 (29%), Positives = 70/144 (48%), Gaps = 5/144 (3%)
Query: 237 PDRLSCKDI--DECS-ITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
PD SC + D+CS + +C++ ++ C C G+ +
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNI 167
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C C NTPGSYHC+C+ G+ + ++ + C+D+DEC+ CG C+N G + C
Sbjct: 168 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
Query: 354 CTDGLVPSAAGAKPTCQDIDECAD 377
C +G + +C+DIDEC++
Sbjct: 228 CPEGYRYNL--KSKSCEDIDECSE 249
Score = 86.6 bits (205), Expect = 2e-16
Identities = 46/134 (34%), Positives = 66/134 (49%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECL--TN-NGGCHPRAT 491
D+C C+ C + SF C C+ GW+G+ CE D++EC +N NGGC
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGGCSQ--I 174
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
C NT GS+ C C G+ + C D+DEC+ P++C C N PG +EC+
Sbjct: 175 CDNTPGSYHCSCKNGFV-------MLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
Query: 552 CDVGFTRAADGRSC 565
C G+ +SC
Sbjct: 228 CPEGYRYNLKSKSC 241
Score = 78.2 bits (184), Expect = 7e-14
Identities = 46/162 (28%), Positives = 64/162 (39%), Gaps = 5/162 (3%)
Query: 218 CVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ 277
C + SF C C G + + + S +G CS C+N G+Y C C G+
Sbjct: 134 CKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVM 192
Query: 278 STVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGAR 336
+ K C + C N PG + C C EG+ +SC DIDEC+
Sbjct: 193 LSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENM- 251
Query: 337 PCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
C C N G YTC C A + +C+ + C L
Sbjct: 252 -CAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPL 291
>AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein.
Length = 497
Score = 114 bits (275), Expect = 7e-25
Identities = 57/160 (35%), Positives = 82/160 (51%), Gaps = 9/160 (5%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR--CVNTAGSFRCECGHGM 233
C + + SFTC C+PG++ + K DI+EC D + G C NT GS+ C C +G
Sbjct: 134 CKDGKASFTCTCKPGWQGE---KCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
+ ++ CKD+DECS+ IC C+N G ++C C EGY + +KS
Sbjct: 191 VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY-RYNLKS-KSCEDIDECS 248
Query: 294 XXRCQHSCVNTPGSYHCTC--REGWHLRADGRSCRDIDEC 331
C CVN PG Y C C ++G+ L D +SC + C
Sbjct: 249 ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
Score = 104 bits (249), Expect = 1e-21
Identities = 54/156 (34%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 120 NECAAFP-GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD--C 176
++C+ P G+ C++ FTC C PG++ + D+NEC+ + G C
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEF---DINECKDPSNINGGCSQIC 175
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS+ C C+ G+ K C D+DEC+ ++C C N G F CEC G
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 235
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
SC+DIDECS +C+ C N G Y C CD
Sbjct: 236 LKSKSCEDIDECS--ENMCAQ-LCVNYPGGYTCYCD 268
Score = 101 bits (241), Expect = 9e-21
Identities = 68/192 (35%), Positives = 88/192 (45%), Gaps = 40/192 (20%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQ--CRNTVGSYTCTCTD 356
SC + S+ CTC+ GW G C DI+EC + GG C NT GSY C+C +
Sbjct: 133 SCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 188
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G V K C+D+DEC+ L+ P +CG C N G F C
Sbjct: 189 GFV--MLSNKKDCKDVDECS-------------LK-------PSICGTAVCKNIPGDFEC 226
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGA 471
+CP+GY + +C D DEC C A C+N PG + C C DG +G D
Sbjct: 227 ECPEGYRYN-LKSKSCEDIDECSENMC----AQLCVNYPGGYTCYC-DGKKGFKLAQDQK 280
Query: 472 TCEDVDECLTNN 483
+CE V CL N
Sbjct: 281 SCEVVSVCLPLN 292
Score = 96.7 bits (230), Expect = 2e-19
Identities = 50/138 (36%), Positives = 69/138 (50%), Gaps = 9/138 (6%)
Query: 116 QMEVNEC---AAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
+ ++NEC + G C C N G + C C G+ S C DV+EC + +CG
Sbjct: 155 EFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG 213
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECG-- 230
C N G F C C GY+ + SK C DIDEC++N +C CVN G + C C
Sbjct: 214 TAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MC-AQLCVNYPGGYTCYCDGK 270
Query: 231 HGMELAPDRLSCKDIDEC 248
G +LA D+ SC+ + C
Sbjct: 271 KGFKLAQDQKSCEVVSVC 288
Score = 94.7 bits (225), Expect = 8e-19
Identities = 63/169 (37%), Positives = 82/169 (48%), Gaps = 22/169 (13%)
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DEC-ELGTCDCHPAADCINLPGSFQC 460
G SC + SF C C G+ QG C D +EC + + + C N PGS+ C
Sbjct: 130 GYMSCKDGKASFTCTCKPGW-----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHC 184
Query: 461 RCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C++G+ + C+DVDEC C A C N G F C C GY+ Y L++
Sbjct: 185 SCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPGDFECECPEGYR---YNLKSK- 239
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD--VGFTRAADGRSC 565
SC DIDEC+ + +C C N PGGY C CD GF A D +SC
Sbjct: 240 ---SCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 89.8 bits (213), Expect = 2e-17
Identities = 42/144 (29%), Positives = 70/144 (48%), Gaps = 5/144 (3%)
Query: 237 PDRLSCKDI--DECS-ITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
PD SC + D+CS + +C++ ++ C C G+ +
Sbjct: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNI 167
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C C NTPGSYHC+C+ G+ + ++ + C+D+DEC+ CG C+N G + C
Sbjct: 168 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
Query: 354 CTDGLVPSAAGAKPTCQDIDECAD 377
C +G + +C+DIDEC++
Sbjct: 228 CPEGYRYNL--KSKSCEDIDECSE 249
Score = 86.6 bits (205), Expect = 2e-16
Identities = 46/134 (34%), Positives = 66/134 (49%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECL--TN-NGGCHPRAT 491
D+C C+ C + SF C C+ GW+G+ CE D++EC +N NGGC
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGGCSQ--I 174
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
C NT GS+ C C G+ + C D+DEC+ P++C C N PG +EC+
Sbjct: 175 CDNTPGSYHCSCKNGFV-------MLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
Query: 552 CDVGFTRAADGRSC 565
C G+ +SC
Sbjct: 228 CPEGYRYNLKSKSC 241
Score = 78.2 bits (184), Expect = 7e-14
Identities = 46/162 (28%), Positives = 64/162 (39%), Gaps = 5/162 (3%)
Query: 218 CVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ 277
C + SF C C G + + + S +G CS C+N G+Y C C G+
Sbjct: 134 CKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVM 192
Query: 278 STVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGAR 336
+ K C + C N PG + C C EG+ +SC DIDEC+
Sbjct: 193 LSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENM- 251
Query: 337 PCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
C C N G YTC C A + +C+ + C L
Sbjct: 252 -CAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPL 291
>X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA for
protein S. ).
Length = 650
Score = 114 bits (274), Expect = 9e-25
Identities = 56/160 (35%), Positives = 83/160 (51%), Gaps = 9/160 (5%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR--CVNTAGSFRCECGHGM 233
C + + SFTC C+PG++ + K DI+EC D + G C NT GS+ C C +G
Sbjct: 108 CKDGKASFTCTCKPGWQGE---KCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 164
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
+ ++ CKD+DECS+ IC C+N +G ++C C EGY + +KS
Sbjct: 165 VMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGY-RYNLKS-KSCEDIDECS 222
Query: 294 XXRCQHSCVNTPGSYHCTC--REGWHLRADGRSCRDIDEC 331
C CVN PG + C C ++G+ L D +SC + C
Sbjct: 223 ENMCAQLCVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVC 262
Score = 102 bits (244), Expect = 4e-21
Identities = 53/156 (33%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 120 NECAAFP-GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD--C 176
++C+ P G+ C++ FTC C PG++ + D+NEC+ + G C
Sbjct: 93 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEF---DINECKDPSNINGGCSQIC 149
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS+ C C+ G+ K C D+DEC+ ++C C N G F CEC G
Sbjct: 150 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYN 209
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
SC+DIDECS +C+ C N G + C CD
Sbjct: 210 LKSKSCEDIDECS--ENMCAQ-LCVNYPGGHTCYCD 242
Score = 101 bits (242), Expect = 7e-21
Identities = 68/192 (35%), Positives = 88/192 (45%), Gaps = 40/192 (20%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQ--CRNTVGSYTCTCTD 356
SC + S+ CTC+ GW G C DI+EC + GG C NT GSY C+C +
Sbjct: 107 SCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 162
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G V K C+D+DEC+ L+ P +CG C N +G F C
Sbjct: 163 GFV--MLSNKKDCKDVDECS-------------LK-------PSICGTAVCKNILGDFEC 200
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGA 471
+CP+GY + +C D DEC C A C+N PG C C DG +G D
Sbjct: 201 ECPEGYRYN-LKSKSCEDIDECSENMC----AQLCVNYPGGHTCYC-DGKKGFKLAQDQK 254
Query: 472 TCEDVDECLTNN 483
+CE V CL N
Sbjct: 255 SCEVVSVCLPLN 266
Score = 94.3 bits (224), Expect = 1e-18
Identities = 50/138 (36%), Positives = 68/138 (49%), Gaps = 9/138 (6%)
Query: 116 QMEVNEC---AAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
+ ++NEC + G C C N G + C C G+ S C DV+EC + +CG
Sbjct: 129 EFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG 187
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECG-- 230
C N G F C C GY+ + SK C DIDEC++N +C CVN G C C
Sbjct: 188 TAVCKNILGDFECECPEGYRYNLKSKSCEDIDECSEN--MC-AQLCVNYPGGHTCYCDGK 244
Query: 231 HGMELAPDRLSCKDIDEC 248
G +LA D+ SC+ + C
Sbjct: 245 KGFKLAQDQKSCEVVSVC 262
Score = 91.5 bits (217), Expect = 7e-18
Identities = 62/169 (36%), Positives = 82/169 (48%), Gaps = 22/169 (13%)
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DEC-ELGTCDCHPAADCINLPGSFQC 460
G SC + SF C C G+ QG C D +EC + + + C N PGS+ C
Sbjct: 104 GYMSCKDGKASFTCTCKPGW-----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHC 158
Query: 461 RCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C++G+ + C+DVDEC C A C N G F C C GY+ Y L++
Sbjct: 159 SCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNILGDFECECPEGYR---YNLKSK- 213
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD--VGFTRAADGRSC 565
SC DIDEC+ + +C C N PGG+ C CD GF A D +SC
Sbjct: 214 ---SCEDIDECSEN--MCAQ-LCVNYPGGHTCYCDGKKGFKLAQDQKSC 256
Score = 91.1 bits (216), Expect = 1e-17
Identities = 42/144 (29%), Positives = 71/144 (49%), Gaps = 5/144 (3%)
Query: 237 PDRLSCKDI--DECS-ITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
PD SC + D+CS + +C++ ++ C C G+ +
Sbjct: 82 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNI 141
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C C NTPGSYHC+C+ G+ + ++ + C+D+DEC+ CG C+N +G + C
Sbjct: 142 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECE 201
Query: 354 CTDGLVPSAAGAKPTCQDIDECAD 377
C +G + +C+DIDEC++
Sbjct: 202 CPEGYRYNL--KSKSCEDIDECSE 223
Score = 82.6 bits (195), Expect = 3e-15
Identities = 45/134 (33%), Positives = 65/134 (48%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECL--TN-NGGCHPRAT 491
D+C C+ C + SF C C+ GW+G+ CE D++EC +N NGGC
Sbjct: 93 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGGCSQ--I 148
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
C NT GS+ C C G+ + C D+DEC+ P++C C N G +EC+
Sbjct: 149 CDNTPGSYHCSCKNGFV-------MLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECE 201
Query: 552 CDVGFTRAADGRSC 565
C G+ +SC
Sbjct: 202 CPEGYRYNLKSKSC 215
Score = 72.1 bits (169), Expect = 5e-12
Identities = 44/162 (27%), Positives = 63/162 (38%), Gaps = 5/162 (3%)
Query: 218 CVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ 277
C + SF C C G + + + S +G CS C+N G+Y C C G+
Sbjct: 108 CKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVM 166
Query: 278 STVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGAR 336
+ K C + C N G + C C EG+ +SC DIDEC+
Sbjct: 167 LSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECSENM- 225
Query: 337 PCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
C C N G +TC C A + +C+ + C L
Sbjct: 226 -CAQ-LCVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVCLPL 265
>M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein.
Length = 650
Score = 114 bits (274), Expect = 9e-25
Identities = 56/160 (35%), Positives = 83/160 (51%), Gaps = 9/160 (5%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR--CVNTAGSFRCECGHGM 233
C + + SFTC C+PG++ + K DI+EC D + G C NT GS+ C C +G
Sbjct: 108 CKDGKASFTCTCKPGWQGE---KCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 164
Query: 234 ELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
+ ++ CKD+DECS+ IC C+N +G ++C C EGY + +KS
Sbjct: 165 VMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGY-RYNLKS-KSCEDIDECS 222
Query: 294 XXRCQHSCVNTPGSYHCTC--REGWHLRADGRSCRDIDEC 331
C CVN PG + C C ++G+ L D +SC + C
Sbjct: 223 ENMCAQLCVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVC 262
Score = 102 bits (244), Expect = 4e-21
Identities = 53/156 (33%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 120 NECAAFP-GLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD--C 176
++C+ P G+ C++ FTC C PG++ + D+NEC+ + G C
Sbjct: 93 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEF---DINECKDPSNINGGCSQIC 149
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
NT GS+ C C+ G+ K C D+DEC+ ++C C N G F CEC G
Sbjct: 150 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYN 209
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
SC+DIDECS +C+ C N G + C CD
Sbjct: 210 LKSKSCEDIDECS--ENMCAQ-LCVNYPGGHTCYCD 242
Score = 101 bits (242), Expect = 7e-21
Identities = 68/192 (35%), Positives = 88/192 (45%), Gaps = 40/192 (20%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQ--CRNTVGSYTCTCTD 356
SC + S+ CTC+ GW G C DI+EC + GG C NT GSY C+C +
Sbjct: 107 SCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 162
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
G V K C+D+DEC+ L+ P +CG C N +G F C
Sbjct: 163 GFV--MLSNKKDCKDVDECS-------------LK-------PSICGTAVCKNILGDFEC 200
Query: 417 QCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGA 471
+CP+GY + +C D DEC C A C+N PG C C DG +G D
Sbjct: 201 ECPEGYRYN-LKSKSCEDIDECSENMC----AQLCVNYPGGHTCYC-DGKKGFKLAQDQK 254
Query: 472 TCEDVDECLTNN 483
+CE V CL N
Sbjct: 255 SCEVVSVCLPLN 266
Score = 94.3 bits (224), Expect = 1e-18
Identities = 50/138 (36%), Positives = 68/138 (49%), Gaps = 9/138 (6%)
Query: 116 QMEVNEC---AAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG 172
+ ++NEC + G C C N G + C C G+ S C DV+EC + +CG
Sbjct: 129 EFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG 187
Query: 173 DGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECG-- 230
C N G F C C GY+ + SK C DIDEC++N +C CVN G C C
Sbjct: 188 TAVCKNILGDFECECPEGYRYNLKSKSCEDIDECSEN--MC-AQLCVNYPGGHTCYCDGK 244
Query: 231 HGMELAPDRLSCKDIDEC 248
G +LA D+ SC+ + C
Sbjct: 245 KGFKLAQDQKSCEVVSVC 262
Score = 91.5 bits (217), Expect = 7e-18
Identities = 62/169 (36%), Positives = 82/169 (48%), Gaps = 22/169 (13%)
Query: 403 GAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DEC-ELGTCDCHPAADCINLPGSFQC 460
G SC + SF C C G+ QG C D +EC + + + C N PGS+ C
Sbjct: 104 GYMSCKDGKASFTCTCKPGW-----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHC 158
Query: 461 RCRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
C++G+ + C+DVDEC C A C N G F C C GY+ Y L++
Sbjct: 159 SCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNILGDFECECPEGYR---YNLKSK- 213
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD--VGFTRAADGRSC 565
SC DIDEC+ + +C C N PGG+ C CD GF A D +SC
Sbjct: 214 ---SCEDIDECSEN--MCAQ-LCVNYPGGHTCYCDGKKGFKLAQDQKSC 256
Score = 91.1 bits (216), Expect = 1e-17
Identities = 42/144 (29%), Positives = 71/144 (49%), Gaps = 5/144 (3%)
Query: 237 PDRLSCKDI--DECS-ITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXX 293
PD SC + D+CS + +C++ ++ C C G+ +
Sbjct: 82 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNI 141
Query: 294 XXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCT 353
C C NTPGSYHC+C+ G+ + ++ + C+D+DEC+ CG C+N +G + C
Sbjct: 142 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECE 201
Query: 354 CTDGLVPSAAGAKPTCQDIDECAD 377
C +G + +C+DIDEC++
Sbjct: 202 CPEGYRYNL--KSKSCEDIDECSE 223
Score = 82.6 bits (195), Expect = 3e-15
Identities = 45/134 (33%), Positives = 65/134 (48%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECL--TN-NGGCHPRAT 491
D+C C+ C + SF C C+ GW+G+ CE D++EC +N NGGC
Sbjct: 93 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGGCSQ--I 148
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
C NT GS+ C C G+ + C D+DEC+ P++C C N G +EC+
Sbjct: 149 CDNTPGSYHCSCKNGFV-------MLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECE 201
Query: 552 CDVGFTRAADGRSC 565
C G+ +SC
Sbjct: 202 CPEGYRYNLKSKSC 215
Score = 72.1 bits (169), Expect = 5e-12
Identities = 44/162 (27%), Positives = 63/162 (38%), Gaps = 5/162 (3%)
Query: 218 CVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQ 277
C + SF C C G + + + S +G CS C+N G+Y C C G+
Sbjct: 108 CKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVM 166
Query: 278 STVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGAR 336
+ K C + C N G + C C EG+ +SC DIDEC+
Sbjct: 167 LSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECSENM- 225
Query: 337 PCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADL 378
C C N G +TC C A + +C+ + C L
Sbjct: 226 -CAQ-LCVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVCLPL 265
>D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein.
Length = 815
Score = 113 bits (272), Expect = 2e-24
Identities = 62/175 (35%), Positives = 80/175 (45%), Gaps = 25/175 (14%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N VC C DG+ E C D DEC G C C+N PGSF C C+ G+
Sbjct: 412 CRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY 471
Query: 467 -RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC------- 518
R D +C + DEC+TN C A C NT G C+C GY G+G + C
Sbjct: 472 IRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNG 531
Query: 519 --CVY-------------SC-VDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
C+ SC DIDEC++ C++ +C N PG Y C+C G+
Sbjct: 532 GACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGY 586
Score = 110 bits (264), Expect = 1e-23
Identities = 101/361 (27%), Positives = 139/361 (38%), Gaps = 39/361 (10%)
Query: 197 SKICVDIDECADNDALCRGGRCVNTAGSFRCEC--GHGMELAPDRLS-CKDIDECSITSG 253
S +CV + EC D + V ++G +C H + L+ CK D CS
Sbjct: 352 SGVCV-LYECKDQTM-----KLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 405
Query: 254 ICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHC 310
N C N C C +G+ A ++ C+ + CVNTPGS+ C
Sbjct: 406 CMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMC 465
Query: 311 TCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTC 369
C+ G+ +R D SC + DEC C C NTVG + C C G + K C
Sbjct: 466 ICKTGY-IRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFC 524
Query: 370 QD--IDECADLISTIIMMSVDELQKSVDPQIPELCGAG--------SCHNTIGSFVCQCP 419
+D + A + + + S + I E C G +C N G + C+C
Sbjct: 525 KDGCRNGGACIAANVCACPQGFTGPSCETDIDE-CSDGFVQCDSRANCINLPGWYHCECR 583
Query: 420 DGY---SVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
DGY + G +C D DEC G C C NL G + CRC G G D
Sbjct: 584 DGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDG 643
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC-CVYSCVDIDECAN-DPT 534
+ +NG + D C C G+ R VC C VD+ C DP
Sbjct: 644 K--VKHNG----QIWVLENDRCSVCSCQNGFV---MCRRMVCDCENPTVDLFCCPECDPR 694
Query: 535 L 535
L
Sbjct: 695 L 695
Score = 109 bits (262), Expect = 3e-23
Identities = 77/240 (32%), Positives = 103/240 (42%), Gaps = 32/240 (13%)
Query: 143 CDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKA-DDFSKICV 201
C GY+ S+ H C++ + C N C CR G++A + + C
Sbjct: 391 CKVCKGYDFCSERHNCME------------NSICRNLNDRAVCSCRDGFRALREDNAYCE 438
Query: 202 DIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGA 259
DIDECA+ CR CVNT GSF C C G + D SC + DEC C N
Sbjct: 439 DIDECAEGRHYCRENTMCVNTPGSFMCICKTGY-IRIDDYSCTEHDECITNQHNCDENAL 497
Query: 260 CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
C N +G + CVC GY + R +C+ + C C +G+
Sbjct: 498 CFNTVGGHNCVCKPGYT-----GNGTTCKAFCKDGCRNGGACI---AANVCACPQGF--- 546
Query: 320 ADGRSCR-DIDECAGGARPCGG-GQCRNTVGSYTCTCTDGLVPSA--AGAKPTCQDIDEC 375
G SC DIDEC+ G C C N G Y C C DG + + + +C+DIDEC
Sbjct: 547 -TGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDEC 605
Score = 107 bits (256), Expect = 1e-22
Identities = 86/259 (33%), Positives = 106/259 (40%), Gaps = 42/259 (16%)
Query: 301 CVNTPGSYHCTCREGWH-LRADGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGL 358
C N C+CR+G+ LR D C DIDECA G C C NT GS+ C C G
Sbjct: 412 CRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY 471
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
+ +C + DEC I+ Q + D C NT+G C C
Sbjct: 472 IRID---DYSCTEHDEC---ITN---------QHNCDEN-------ALCFNTVGGHNCVC 509
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVD 477
GY+ G T C+ G C CI + C C G+ G +CE D+D
Sbjct: 510 KPGYT-----GNGTTCKAFCKDG---CRNGGACI---AANVCACPQGFTGP--SCETDID 556
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC C RA C N G + C C GY +G + SC DIDEC C
Sbjct: 557 ECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSG---ESCEDIDECGTGRHSCA 613
Query: 538 NGH-CSNTPGGYECDCDVG 555
N C N GGY+C C G
Sbjct: 614 NDTICFNLDGGYDCRCPHG 632
Score = 79.0 bits (186), Expect = 4e-14
Identities = 66/215 (30%), Positives = 87/215 (40%), Gaps = 26/215 (12%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
+++ECA C C N G F C C GY + +++C + +EC C +
Sbjct: 439 DIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRID-DYSCTEHDECITNQHNCDENAL 497
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGME 234
C NT G C C+PGY + C C D CR GG C+ + C C G
Sbjct: 498 CFNTVGGHNCVCKPGYTGN--GTTCKAF--CKDG---CRNGGACI---AANVCACPQGF- 546
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
P SC+ DIDECS C + A C N G Y C C +GY + + S
Sbjct: 547 TGP---SCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDID 603
Query: 293 XXXRCQHSCV------NTPGSYHCTCREGWHLRAD 321
+HSC N G Y C C G + D
Sbjct: 604 ECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD 638
>D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2
protein.
Length = 816
Score = 113 bits (272), Expect = 2e-24
Identities = 62/175 (35%), Positives = 80/175 (45%), Gaps = 25/175 (14%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N VC C DG+ E C D DEC G C C+N PGSF C C+ G+
Sbjct: 413 CRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY 472
Query: 467 -RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC------- 518
R D +C + DEC+TN C A C NT G C+C GY G+G + C
Sbjct: 473 IRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNG 532
Query: 519 --CVY-------------SC-VDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
C+ SC DIDEC++ C++ +C N PG Y C+C G+
Sbjct: 533 GACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGY 587
Score = 110 bits (264), Expect = 1e-23
Identities = 101/361 (27%), Positives = 139/361 (38%), Gaps = 39/361 (10%)
Query: 197 SKICVDIDECADNDALCRGGRCVNTAGSFRCEC--GHGMELAPDRLS-CKDIDECSITSG 253
S +CV + EC D + V ++G +C H + L+ CK D CS
Sbjct: 353 SGVCV-LYECKDQTM-----KLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 406
Query: 254 ICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHC 310
N C N C C +G+ A ++ C+ + CVNTPGS+ C
Sbjct: 407 CMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMC 466
Query: 311 TCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTC 369
C+ G+ +R D SC + DEC C C NTVG + C C G + K C
Sbjct: 467 ICKTGY-IRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFC 525
Query: 370 QD--IDECADLISTIIMMSVDELQKSVDPQIPELCGAG--------SCHNTIGSFVCQCP 419
+D + A + + + S + I E C G +C N G + C+C
Sbjct: 526 KDGCRNGGACIAANVCACPQGFTGPSCETDIDE-CSDGFVQCDSRANCINLPGWYHCECR 584
Query: 420 DGY---SVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
DGY + G +C D DEC G C C NL G + CRC G G D
Sbjct: 585 DGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDG 644
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC-CVYSCVDIDECAN-DPT 534
+ +NG + D C C G+ R VC C VD+ C DP
Sbjct: 645 K--VKHNG----QIWVLENDRCSVCSCQNGFV---MCRRMVCDCENPTVDLFCCPECDPR 695
Query: 535 L 535
L
Sbjct: 696 L 696
Score = 109 bits (262), Expect = 3e-23
Identities = 77/240 (32%), Positives = 103/240 (42%), Gaps = 32/240 (13%)
Query: 143 CDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKA-DDFSKICV 201
C GY+ S+ H C++ + C N C CR G++A + + C
Sbjct: 392 CKVCKGYDFCSERHNCME------------NSICRNLNDRAVCSCRDGFRALREDNAYCE 439
Query: 202 DIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGA 259
DIDECA+ CR CVNT GSF C C G + D SC + DEC C N
Sbjct: 440 DIDECAEGRHYCRENTMCVNTPGSFMCICKTGY-IRIDDYSCTEHDECITNQHNCDENAL 498
Query: 260 CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
C N +G + CVC GY + R +C+ + C C +G+
Sbjct: 499 CFNTVGGHNCVCKPGYT-----GNGTTCKAFCKDGCRNGGACI---AANVCACPQGF--- 547
Query: 320 ADGRSCR-DIDECAGGARPCGG-GQCRNTVGSYTCTCTDGLVPSA--AGAKPTCQDIDEC 375
G SC DIDEC+ G C C N G Y C C DG + + + +C+DIDEC
Sbjct: 548 -TGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDEC 606
Score = 107 bits (256), Expect = 1e-22
Identities = 86/259 (33%), Positives = 106/259 (40%), Gaps = 42/259 (16%)
Query: 301 CVNTPGSYHCTCREGWH-LRADGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGL 358
C N C+CR+G+ LR D C DIDECA G C C NT GS+ C C G
Sbjct: 413 CRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY 472
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
+ +C + DEC I+ Q + D C NT+G C C
Sbjct: 473 IRID---DYSCTEHDEC---ITN---------QHNCDEN-------ALCFNTVGGHNCVC 510
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVD 477
GY+ G T C+ G C CI + C C G+ G +CE D+D
Sbjct: 511 KPGYT-----GNGTTCKAFCKDG---CRNGGACI---AANVCACPQGFTGP--SCETDID 557
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC C RA C N G + C C GY +G + SC DIDEC C
Sbjct: 558 ECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSG---ESCEDIDECGTGRHSCA 614
Query: 538 NGH-CSNTPGGYECDCDVG 555
N C N GGY+C C G
Sbjct: 615 NDTICFNLDGGYDCRCPHG 633
Score = 79.0 bits (186), Expect = 4e-14
Identities = 66/215 (30%), Positives = 87/215 (40%), Gaps = 26/215 (12%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
+++ECA C C N G F C C GY + +++C + +EC C +
Sbjct: 440 DIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRID-DYSCTEHDECITNQHNCDENAL 498
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGME 234
C NT G C C+PGY + C C D CR GG C+ + C C G
Sbjct: 499 CFNTVGGHNCVCKPGYTGN--GTTCKAF--CKDG---CRNGGACI---AANVCACPQGF- 547
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
P SC+ DIDECS C + A C N G Y C C +GY + + S
Sbjct: 548 TGP---SCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDID 604
Query: 293 XXXRCQHSCV------NTPGSYHCTCREGWHLRAD 321
+HSC N G Y C C G + D
Sbjct: 605 ECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD 639
>BC053933-1|AAH53933.1| 239|Homo sapiens EMR2 protein protein.
Length = 239
Score = 113 bits (272), Expect = 2e-24
Identities = 70/183 (38%), Positives = 89/183 (48%), Gaps = 39/183 (21%)
Query: 300 SCVNTPGSYHCTCREGWH-----LRADGRSCRDIDECAGGAR-PCGG-GQCRNTVGSYTC 352
SCVN C C G+ + +C DI+ECA ++ CG C NT GSY C
Sbjct: 38 SCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDC 94
Query: 353 TCTDGLVPSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA- 404
C+ G P +GAK TCQD+DEC Q P LC +
Sbjct: 95 VCSPGYEP-VSGAKTFKNESENTCQDVDECQ--------------------QNPRLCKSY 133
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
G+C NT+GS+ CQC G+ PE CTD +EC G CH + C+N GS+QCRCR
Sbjct: 134 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 193
Query: 465 GWR 467
GW+
Sbjct: 194 GWQ 196
Score = 112 bits (269), Expect = 4e-24
Identities = 60/151 (39%), Positives = 80/151 (52%), Gaps = 18/151 (11%)
Query: 143 CDCFPGYEKDSK-----NHTCVDVNECEIVDGV-CGD-GDCHNTEGSFTCHCRPGYK--- 192
C C PG+ S+ TC D+NEC + V CG DC NTEGS+ C C PGY+
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 193 -----ADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELAP-DRLSCKDI 245
++ C D+DEC N LC+ G CVNT GS+ C+C G + P D C D+
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV 164
Query: 246 DECSITSGIC-SNGACENQMGTYQCVCDEGY 275
+EC+ C S+ C N +G+YQC C G+
Sbjct: 165 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 195
Score = 95.5 bits (227), Expect = 4e-19
Identities = 49/133 (36%), Positives = 68/133 (51%), Gaps = 13/133 (9%)
Query: 118 EVNECAAFPGL-CGH-GRCRNLLGGFTCDCFPGYE--------KDSKNHTCVDVNECEIV 167
++NECA + CG C N G + C C PGYE K+ +TC DV+EC+
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYK-ADDFSKICVDIDECADNDALCRGG-RCVNTAGS 224
+C G C NT GS+TC C PG+K + K+C D++EC C C+N GS
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 225 FRCECGHGMELAP 237
++C C G + P
Sbjct: 187 YQCRCRPGWQPIP 199
Score = 85.0 bits (201), Expect = 6e-16
Identities = 53/162 (32%), Positives = 71/162 (43%), Gaps = 22/162 (13%)
Query: 411 IGSFVCQCPDGYSVKPE----QGPACTDDDECE-LGTCDCHPAADCINLPGSFQCRCRDG 465
+ + C+C G+S E C D +EC L C +DC N GS+ C C G
Sbjct: 40 VNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPG 99
Query: 466 WRG-DGA---------TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
+ GA TC+DVDEC N C TC NT GS+ C C G+K +
Sbjct: 100 YEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK 159
Query: 516 TVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVGF 556
C D++EC + C + HC N G Y+C C G+
Sbjct: 160 V------CTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 195
Score = 84.6 bits (200), Expect = 8e-16
Identities = 56/160 (35%), Positives = 72/160 (45%), Gaps = 18/160 (11%)
Query: 218 CVNTAGSFRCECGHGM--ELAPDRL-SCKDIDECSITSGI-CSNGA-CENQMGTYQCVCD 272
CVN A + RC G E+ + +C DI+EC+ S + C + C N G+Y CVC
Sbjct: 39 CVN-ATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCS 97
Query: 273 EGYAQ-STVKSHXXXXXXXXXXXXRCQHS---------CVNTPGSYHCTCREGWH-LRAD 321
GY S K+ CQ + CVNT GSY C C G+ + D
Sbjct: 98 PGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPED 157
Query: 322 GRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGLVP 360
+ C D++EC G PC C N VGSY C C G P
Sbjct: 158 PKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQP 197
Score = 82.2 bits (194), Expect = 4e-15
Identities = 62/196 (31%), Positives = 83/196 (42%), Gaps = 35/196 (17%)
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP-SAAGAKP--TCQDIDECADLISTII 383
+ + G AR C Q + V + C C G S P TC DI+ECA T+
Sbjct: 22 ETQDSRGCARWCP--QDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECA----TLS 75
Query: 384 MMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGY-------SVKPEQGPACTDD 435
+S CG S C NT GS+ C C GY + K E C D
Sbjct: 76 KVS---------------CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATC 492
DEC+ C C+N GS+ C+C G++ D C DV+EC + CH C
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 180
Query: 493 ANTDGSFRCLCDTGYK 508
N GS++C C G++
Sbjct: 181 LNNVGSYQCRCRPGWQ 196
>BC034949-1|AAH34949.1| 239|Homo sapiens EMR2 protein protein.
Length = 239
Score = 113 bits (272), Expect = 2e-24
Identities = 70/183 (38%), Positives = 89/183 (48%), Gaps = 39/183 (21%)
Query: 300 SCVNTPGSYHCTCREGWH-----LRADGRSCRDIDECAGGAR-PCGG-GQCRNTVGSYTC 352
SCVN C C G+ + +C DI+ECA ++ CG C NT GSY C
Sbjct: 38 SCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDC 94
Query: 353 TCTDGLVPSAAGAKP-------TCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA- 404
C+ G P +GAK TCQD+DEC Q P LC +
Sbjct: 95 VCSPGYEP-VSGAKTFKNESENTCQDVDECQ--------------------QNPRLCKSY 133
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
G+C NT+GS+ CQC G+ PE CTD +EC G CH + C+N GS+QCRCR
Sbjct: 134 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 193
Query: 465 GWR 467
GW+
Sbjct: 194 GWQ 196
Score = 112 bits (269), Expect = 4e-24
Identities = 60/151 (39%), Positives = 80/151 (52%), Gaps = 18/151 (11%)
Query: 143 CDCFPGYEKDSK-----NHTCVDVNECEIVDGV-CGD-GDCHNTEGSFTCHCRPGYK--- 192
C C PG+ S+ TC D+NEC + V CG DC NTEGS+ C C PGY+
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 193 -----ADDFSKICVDIDECADNDALCRG-GRCVNTAGSFRCECGHGMELAP-DRLSCKDI 245
++ C D+DEC N LC+ G CVNT GS+ C+C G + P D C D+
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV 164
Query: 246 DECSITSGIC-SNGACENQMGTYQCVCDEGY 275
+EC+ C S+ C N +G+YQC C G+
Sbjct: 165 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 195
Score = 95.5 bits (227), Expect = 4e-19
Identities = 49/133 (36%), Positives = 68/133 (51%), Gaps = 13/133 (9%)
Query: 118 EVNECAAFPGL-CGH-GRCRNLLGGFTCDCFPGYE--------KDSKNHTCVDVNECEIV 167
++NECA + CG C N G + C C PGYE K+ +TC DV+EC+
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 168 DGVCGD-GDCHNTEGSFTCHCRPGYK-ADDFSKICVDIDECADNDALCRGG-RCVNTAGS 224
+C G C NT GS+TC C PG+K + K+C D++EC C C+N GS
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 225 FRCECGHGMELAP 237
++C C G + P
Sbjct: 187 YQCRCRPGWQPIP 199
Score = 85.0 bits (201), Expect = 6e-16
Identities = 53/162 (32%), Positives = 71/162 (43%), Gaps = 22/162 (13%)
Query: 411 IGSFVCQCPDGYSVKPE----QGPACTDDDECE-LGTCDCHPAADCINLPGSFQCRCRDG 465
+ + C+C G+S E C D +EC L C +DC N GS+ C C G
Sbjct: 40 VNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPG 99
Query: 466 WRG-DGA---------TCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLR 515
+ GA TC+DVDEC N C TC NT GS+ C C G+K +
Sbjct: 100 YEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK 159
Query: 516 TVCCVYSCVDIDECANDPTLCENG-HCSNTPGGYECDCDVGF 556
C D++EC + C + HC N G Y+C C G+
Sbjct: 160 V------CTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 195
Score = 84.6 bits (200), Expect = 8e-16
Identities = 56/160 (35%), Positives = 72/160 (45%), Gaps = 18/160 (11%)
Query: 218 CVNTAGSFRCECGHGM--ELAPDRL-SCKDIDECSITSGI-CSNGA-CENQMGTYQCVCD 272
CVN A + RC G E+ + +C DI+EC+ S + C + C N G+Y CVC
Sbjct: 39 CVN-ATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCS 97
Query: 273 EGYAQ-STVKSHXXXXXXXXXXXXRCQHS---------CVNTPGSYHCTCREGWH-LRAD 321
GY S K+ CQ + CVNT GSY C C G+ + D
Sbjct: 98 PGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPED 157
Query: 322 GRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGLVP 360
+ C D++EC G PC C N VGSY C C G P
Sbjct: 158 PKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQP 197
Score = 82.2 bits (194), Expect = 4e-15
Identities = 62/196 (31%), Positives = 83/196 (42%), Gaps = 35/196 (17%)
Query: 327 DIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVP-SAAGAKP--TCQDIDECADLISTII 383
+ + G AR C Q + V + C C G S P TC DI+ECA T+
Sbjct: 22 ETQDSRGCARWCP--QDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECA----TLS 75
Query: 384 MMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCPDGY-------SVKPEQGPACTDD 435
+S CG S C NT GS+ C C GY + K E C D
Sbjct: 76 KVS---------------CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWR---GDGATCEDVDECLTNNGGCHPRATC 492
DEC+ C C+N GS+ C+C G++ D C DV+EC + CH C
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 180
Query: 493 ANTDGSFRCLCDTGYK 508
N GS++C C G++
Sbjct: 181 LNNVGSYQCRCRPGWQ 196
>BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein.
Length = 816
Score = 113 bits (272), Expect = 2e-24
Identities = 62/175 (35%), Positives = 80/175 (45%), Gaps = 25/175 (14%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N VC C DG+ E C D DEC G C C+N PGSF C C+ G+
Sbjct: 413 CRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY 472
Query: 467 -RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC------- 518
R D +C + DEC+TN C A C NT G C+C GY G+G + C
Sbjct: 473 IRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNG 532
Query: 519 --CVY-------------SC-VDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
C+ SC DIDEC++ C++ +C N PG Y C+C G+
Sbjct: 533 GACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGY 587
Score = 110 bits (264), Expect = 1e-23
Identities = 101/361 (27%), Positives = 139/361 (38%), Gaps = 39/361 (10%)
Query: 197 SKICVDIDECADNDALCRGGRCVNTAGSFRCEC--GHGMELAPDRLS-CKDIDECSITSG 253
S +CV + EC D + V ++G +C H + L+ CK D CS
Sbjct: 353 SGVCV-LYECKDQTM-----KLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 406
Query: 254 ICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHC 310
N C N C C +G+ A ++ C+ + CVNTPGS+ C
Sbjct: 407 CMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMC 466
Query: 311 TCREGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTC 369
C+ G+ +R D SC + DEC C C NTVG + C C G + K C
Sbjct: 467 ICKTGY-IRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFC 525
Query: 370 QD--IDECADLISTIIMMSVDELQKSVDPQIPELCGAG--------SCHNTIGSFVCQCP 419
+D + A + + + S + I E C G +C N G + C+C
Sbjct: 526 KDGCRNGGACIAANVCACPQGFTGPSCETDIDE-CSDGFVQCDSRANCINLPGWYHCECR 584
Query: 420 DGY---SVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDV 476
DGY + G +C D DEC G C C NL G + CRC G G D
Sbjct: 585 DGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDG 644
Query: 477 DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC-CVYSCVDIDECAN-DPT 534
+ +NG + D C C G+ R VC C VD+ C DP
Sbjct: 645 K--VKHNG----QIWVLENDRCSVCSCQNGFV---MCRRMVCDCENPTVDLFCCPECDPR 695
Query: 535 L 535
L
Sbjct: 696 L 696
Score = 109 bits (262), Expect = 3e-23
Identities = 77/240 (32%), Positives = 103/240 (42%), Gaps = 32/240 (13%)
Query: 143 CDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKA-DDFSKICV 201
C GY+ S+ H C++ + C N C CR G++A + + C
Sbjct: 392 CKVCKGYDFCSERHNCME------------NSICRNLNDRAVCSCRDGFRALREDNAYCE 439
Query: 202 DIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGA 259
DIDECA+ CR CVNT GSF C C G + D SC + DEC C N
Sbjct: 440 DIDECAEGRHYCRENTMCVNTPGSFMCICKTGY-IRIDDYSCTEHDECITNQHNCDENAL 498
Query: 260 CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
C N +G + CVC GY + R +C+ + C C +G+
Sbjct: 499 CFNTVGGHNCVCKPGYT-----GNGTTCKAFCKDGCRNGGACI---AANVCACPQGF--- 547
Query: 320 ADGRSCR-DIDECAGGARPCGG-GQCRNTVGSYTCTCTDGLVPSA--AGAKPTCQDIDEC 375
G SC DIDEC+ G C C N G Y C C DG + + + +C+DIDEC
Sbjct: 548 -TGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDEC 606
Score = 107 bits (256), Expect = 1e-22
Identities = 86/259 (33%), Positives = 106/259 (40%), Gaps = 42/259 (16%)
Query: 301 CVNTPGSYHCTCREGWH-LRADGRSCRDIDECAGGARPCGGG-QCRNTVGSYTCTCTDGL 358
C N C+CR+G+ LR D C DIDECA G C C NT GS+ C C G
Sbjct: 413 CRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY 472
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
+ +C + DEC I+ Q + D C NT+G C C
Sbjct: 473 IRID---DYSCTEHDEC---ITN---------QHNCDEN-------ALCFNTVGGHNCVC 510
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVD 477
GY+ G T C+ G C CI + C C G+ G +CE D+D
Sbjct: 511 KPGYT-----GNGTTCKAFCKDG---CRNGGACI---AANVCACPQGFTGP--SCETDID 557
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE 537
EC C RA C N G + C C GY +G + SC DIDEC C
Sbjct: 558 ECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSG---ESCEDIDECGTGRHSCA 614
Query: 538 NGH-CSNTPGGYECDCDVG 555
N C N GGY+C C G
Sbjct: 615 NDTICFNLDGGYDCRCPHG 633
Score = 79.0 bits (186), Expect = 4e-14
Identities = 66/215 (30%), Positives = 87/215 (40%), Gaps = 26/215 (12%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
+++ECA C C N G F C C GY + +++C + +EC C +
Sbjct: 440 DIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRID-DYSCTEHDECITNQHNCDENAL 498
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGME 234
C NT G C C+PGY + C C D CR GG C+ + C C G
Sbjct: 499 CFNTVGGHNCVCKPGYTGN--GTTCKAF--CKDG---CRNGGACI---AANVCACPQGF- 547
Query: 235 LAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
P SC+ DIDECS C + A C N G Y C C +GY + + S
Sbjct: 548 TGP---SCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDID 604
Query: 293 XXXRCQHSCV------NTPGSYHCTCREGWHLRAD 321
+HSC N G Y C C G + D
Sbjct: 605 ECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD 639
>AK074499-1|BAC11024.1| 636|Homo sapiens protein ( Homo sapiens
cDNA FLJ90018 fis, clone HEMBA1000732, highly similar to
Homo sapiens mRNA for latent transforming growth
factor-beta ).
Length = 636
Score = 113 bits (272), Expect = 2e-24
Identities = 96/347 (27%), Positives = 136/347 (39%), Gaps = 39/347 (11%)
Query: 244 DIDECSITSGICSNGACENQMGTYQCVCDEGY-AQSTVKSHXXXXXXXXXXXXRCQHS-C 301
D+DECS +C +G C N G+++C+C G+ A + S C+ C
Sbjct: 18 DVDECS-EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRC 76
Query: 302 VNTPGSYHCT--CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTC----- 354
N+PGSY C C G+H +G +C D++EC CG C N GS+ C C
Sbjct: 77 ENSPGSYRCVRDCDPGYHAGPEG-TCDDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 135
Query: 355 -----TDGLVP--SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
T VP ++AG P Q + ++ + S Q P G C
Sbjct: 136 EFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRREC 195
Query: 408 H-NTIGSFVCQCPDGYSVKPEQGPACTDDD----ECELGTCDCHPAADCINLPGSFQCRC 462
+ +T C +V Q CT + C + C A+ +L C
Sbjct: 196 YFDTAAPDACDNILARNV-TWQECCCTVGEGWGSGCRIQQCPGTETAEYQSL-----CPH 249
Query: 463 RDGW---RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
G+ GD + DVDEC C NT + C C GY Y + +
Sbjct: 250 GRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY---YHTQRL-- 304
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C+D DECA++ CE G C NT G Y C C+ R C+
Sbjct: 305 --ECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 349
Score = 110 bits (265), Expect = 1e-23
Identities = 50/115 (43%), Positives = 68/115 (59%), Gaps = 5/115 (4%)
Query: 160 DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECAD-NDALCRGGRC 218
DV+EC D +C G C NT+GSF C C PG++A C+D+DEC + ALCR RC
Sbjct: 18 DVDECSEED-LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRC 76
Query: 219 VNTAGSFRC--ECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVC 271
N+ GS+RC +C G P+ +C D++EC G+C CEN G++ CVC
Sbjct: 77 ENSPGSYRCVRDCDPGYHAGPEG-TCDDVNECETLQGVCGAALCENVEGSFLCVC 130
Score = 85.4 bits (202), Expect = 5e-16
Identities = 42/113 (37%), Positives = 58/113 (51%), Gaps = 5/113 (4%)
Query: 160 DVNECEIV-DGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC 218
DV+EC++ D VC G C NT ++C+C GY C+D DECAD + C GGRC
Sbjct: 265 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 324
Query: 219 VNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVC 271
VNT GS+ C C + L + C + S+ + G C ++G VC
Sbjct: 325 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL---GVCWQEVGA-DLVC 373
Score = 85.0 bits (201), Expect = 6e-16
Identities = 43/114 (37%), Positives = 54/114 (47%), Gaps = 4/114 (3%)
Query: 202 DIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITS-GICSNGAC 260
D+DEC++ D LC+ G C NT GSF C C G PD SC D+DEC +C + C
Sbjct: 18 DVDECSEED-LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRC 76
Query: 261 ENQMGTYQCV--CDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTC 312
EN G+Y+CV CD GY + C N GS+ C C
Sbjct: 77 ENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVCGAALCENVEGSFLCVC 130
Score = 83.0 bits (196), Expect = 3e-15
Identities = 44/120 (36%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC-EIVDGVCGDGDC 176
+V+EC+ LC G C N G F C C PG+ +C+DV+EC E +C C
Sbjct: 18 DVDECSE-EDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRC 76
Query: 177 HNTEGSFTC--HCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGME 234
N+ GS+ C C PGY A C D++EC +C C N GSF C C + E
Sbjct: 77 ENSPGSYRCVRDCDPGYHAGP-EGTCDDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 135
Score = 81.8 bits (193), Expect = 6e-15
Identities = 36/79 (45%), Positives = 45/79 (56%), Gaps = 4/79 (5%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNEC---EIVDGVCG 172
++E EC G C +GRC + GFTC CF GY D CVD+NEC E +C
Sbjct: 543 ELEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 601
Query: 173 DGDCHNTEGSFTCHCRPGY 191
+ C NT+GSF C CRPG+
Sbjct: 602 NARCLNTDGSFRCICRPGF 620
Score = 74.5 bits (175), Expect = 9e-13
Identities = 36/74 (48%), Positives = 42/74 (56%), Gaps = 4/74 (5%)
Query: 117 MEVNECAAF-PGLCGHGRCRNLLGGFTC--DCFPGYEKDSKNHTCVDVNECEIVDGVCGD 173
++V+EC P LC RC N G + C DC PGY + TC DVNECE + GVCG
Sbjct: 58 LDVDECRERGPALCRSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVNECETLQGVCGA 116
Query: 174 GDCHNTEGSFTCHC 187
C N EGSF C C
Sbjct: 117 ALCENVEGSFLCVC 130
Score = 73.3 bits (172), Expect = 2e-12
Identities = 35/77 (45%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDA---LCRG 215
++ EC I+DG C +G C FTC C GY+ D CVDI+EC + +A LC
Sbjct: 544 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 602
Query: 216 GRCVNTAGSFRCECGHG 232
RC+NT GSFRC C G
Sbjct: 603 ARCLNTDGSFRCICRPG 619
Score = 72.9 bits (171), Expect = 3e-12
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 202 DIDECA-DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGAC 260
D+DEC D +C+ G CVNTA + C C +G RL C D DEC+ C G C
Sbjct: 265 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 324
Query: 261 ENQMGTYQCVCD 272
N +G+Y C C+
Sbjct: 325 VNTVGSYHCTCE 336
Score = 71.3 bits (167), Expect = 8e-12
Identities = 44/127 (34%), Positives = 55/127 (43%), Gaps = 14/127 (11%)
Query: 430 PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG--DGATCEDVDECLTNNGGCH 487
P D DEC D + C N GSF+C C G R D A+C DVDEC
Sbjct: 14 PCPADVDECSEE--DLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALC 71
Query: 488 PRATCANTDGSFRCL--CDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTP 545
C N+ GS+RC+ CD GY G +C D++EC +C C N
Sbjct: 72 RSQRCENSPGSYRCVRDCDPGYHAGPEG--------TCDDVNECETLQGVCGAALCENVE 123
Query: 546 GGYECDC 552
G + C C
Sbjct: 124 GSFLCVC 130
Score = 66.5 bits (155), Expect = 2e-10
Identities = 40/119 (33%), Positives = 50/119 (42%), Gaps = 6/119 (5%)
Query: 213 CRGGRCVNT-AGSFRCECGHGME-LAP--DRLSCKDIDECSI-TSGICSNGACENQMGTY 267
CR +C T ++ C HG LAP D +D+DEC + +C +G C N Y
Sbjct: 230 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 289
Query: 268 QCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS-CVNTPGSYHCTCREGWHLRADGRSC 325
C C GY T + C+ CVNT GSYHCTC L R C
Sbjct: 290 SCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 348
Score = 64.9 bits (151), Expect = 7e-10
Identities = 37/115 (32%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 118 EVNECAAFPG-LCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+V+EC F +C G C N G++C C GY ++ C+D +EC + C G C
Sbjct: 265 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 324
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
NT GS+ C C P D + CV + + +D L G C G+ C H
Sbjct: 325 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL---GVCWQEVGA-DLVCSH 375
Score = 64.9 bits (151), Expect = 7e-10
Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 201 VDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC---SITSGICSN 257
++ +EC D C GRCV F C C G L R++C DI+EC S +C N
Sbjct: 544 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 602
Query: 258 GACENQMGTYQCVCDEGYAQSTVKSH 283
C N G+++C+C G+A + H
Sbjct: 603 ARCLNTDGSFRCICRPGFAPTHQPHH 628
Score = 57.2 bits (132), Expect = 1e-07
Identities = 29/73 (39%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 439 ELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA--TCEDVDECLTNNGGCH--PRATCAN 494
E G D C+ +P F CRC DG+R D C D++EC A C N
Sbjct: 548 ECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLN 607
Query: 495 TDGSFRCLCDTGY 507
TDGSFRC+C G+
Sbjct: 608 TDGSFRCICRPGF 620
Score = 53.6 bits (123), Expect = 2e-06
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 301 CVNTPGSYHCTCREGWHLRADGRSCRDIDEC--AGGARP-CGGGQCRNTVGSYTCTCTDG 357
CV P + C C +G+ L +C DI+EC A A P C +C NT GS+ C C G
Sbjct: 560 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 619
Query: 358 LVPS 361
P+
Sbjct: 620 FAPT 623
Score = 53.2 bits (122), Expect = 2e-06
Identities = 27/61 (44%), Positives = 34/61 (55%), Gaps = 5/61 (8%)
Query: 506 GYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
G G G GLRT C D+DEC+ + LC++G C+NT G +EC C G D SC
Sbjct: 3 GGAGGGPGLRTPCPA----DVDECSEED-LCQSGICTNTDGSFECICPPGHRAGPDLASC 57
Query: 566 L 566
L
Sbjct: 58 L 58
Score = 46.0 bits (104), Expect = 4e-04
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 14/95 (14%)
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDEC----A 530
+ +EC +G + R C F C C GY+ D + +CVDI+EC A
Sbjct: 545 EAEECGILDGCTNGR--CVRVPEGFTCRCFDGYRLDMTRM-------ACVDINECDEAEA 595
Query: 531 NDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
P LC N C NT G + C C GF C
Sbjct: 596 ASP-LCVNARCLNTDGSFRCICRPGFAPTHQPHHC 629
Score = 45.6 bits (103), Expect = 5e-04
Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDEC---ELGTCDCHPAADCINLPGSF 458
C G C F C+C DGY + + AC D +EC E + C A C+N GSF
Sbjct: 555 CTNGRCVRVPEGFTCRCFDGYRLDMTR-MACVDINECDEAEAASPLC-VNARCLNTDGSF 612
Query: 459 QCRCRDGW 466
+C CR G+
Sbjct: 613 RCICRPGF 620
Score = 37.9 bits (84), Expect = 0.095
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 5/46 (10%)
Query: 117 MEVNEC----AAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTC 158
+++NEC AA P LC + RC N G F C C PG+ + H C
Sbjct: 585 VDINECDEAEAASP-LCVNARCLNTDGSFRCICRPGFAPTHQPHHC 629
Score = 36.3 bits (80), Expect = 0.29
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 2/44 (4%)
Query: 6 CSGPLPTDVLRAVCCCSALGKAWGNQ-RCEPCPKKGTDAYQNLC 48
C L +V CCC+ +G+ WG+ R + CP T YQ+LC
Sbjct: 205 CDNILARNVTWQECCCT-VGEGWGSGCRIQQCPGTETAEYQSLC 247
>AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens
cDNA FLJ32009 fis, clone NT2RP7009498, weakly similar to
FIBULIN-1, ISOFORM A PRECURSOR. ).
Length = 955
Score = 112 bits (270), Expect = 3e-24
Identities = 77/216 (35%), Positives = 96/216 (44%), Gaps = 20/216 (9%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNE---CEIVDGVCGDGDCHN 178
C + G G C L F C G +C D + C G CG+ C
Sbjct: 54 CPGWAPSMGGGHCTLPLCSFGCGS--GICIAPNVCSCQDGEQGATCPETHGPCGEYGCDL 111
Query: 179 TEGSFTCH-----CRPGYKADDFSK--ICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
T C C G+ + + C DIDEC + C G CVNT G F CECG
Sbjct: 112 TCNHGGCQEVARVCPVGFSMTEAAVGIRCTDIDECVTSS--CEG-HCVNTEGGFVCECGP 168
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXX 291
GM+L+ DR SC+D DEC T C C+N +G+Y+C C G+ +
Sbjct: 169 GMQLSADRHSCQDTDECLGTP--CQQ-RCKNSIGSYKCSCRTGFHLHGNRHSCVDVNECR 225
Query: 292 XXXXR--CQHSCVNTPGSYHCTCREGWHLRADGRSC 325
R C HSC NT GS+ CTCR G+ LRAD SC
Sbjct: 226 RPLERRVCHHSCHNTVGSFLCTCRPGFRLRADRVSC 261
Score = 103 bits (248), Expect = 1e-21
Identities = 80/247 (32%), Positives = 105/247 (42%), Gaps = 32/247 (12%)
Query: 332 AGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAK---PTCQDIDECADLISTIIMMSVD 388
A R G C + GS C G PS G P C I+ + D
Sbjct: 34 AAERRRLGPHVCLSGFGS---GCCPGWAPSMGGGHCTLPLCSFGCGSGICIAPNVCSCQD 90
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQ-----CPDGYSV-KPEQGPACTDDDECELGT 442
Q + P+ CG C T CQ CP G+S+ + G CTD DEC +
Sbjct: 91 GEQGATCPETHGPCGEYGCDLTCNHGGCQEVARVCPVGFSMTEAAVGIRCTDIDECVTSS 150
Query: 443 CDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFR 500
C+ H C+N G F C C G + D +C+D DECL C R C N+ GS++
Sbjct: 151 CEGH----CVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTP--CQQR--CKNSIGSYK 202
Query: 501 CLCDTGYKGDGYGLRTVCCVYSCVDIDECAN--DPTLCENGHCSNTPGGYECDCDVGFTR 558
C C TG+ G +SCVD++EC + +C + C NT G + C C GF
Sbjct: 203 CSCRTGFHLHGNR-------HSCVDVNECRRPLERRVCHHS-CHNTVGSFLCTCRPGFRL 254
Query: 559 AADGRSC 565
AD SC
Sbjct: 255 RADRVSC 261
Score = 96.3 bits (229), Expect = 3e-19
Identities = 71/221 (32%), Positives = 87/221 (39%), Gaps = 16/221 (7%)
Query: 138 LGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFS 197
L GF C PG+ C + CG G C C C+ G +
Sbjct: 46 LSGFGSGCCPGWAPSMGGGHCT----LPLCSFGCGSGICIAPN---VCSCQDGEQGATCP 98
Query: 198 KICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSN 257
+ E D C G C A C G M A + C DIDEC +TS C
Sbjct: 99 ETHGPCGEYGC-DLTCNHGGCQEVARV--CPVGFSMTEAAVGIRCTDIDEC-VTSS-CE- 152
Query: 258 GACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWH 317
G C N G + C C G Q + H CQ C N+ GSY C+CR G+H
Sbjct: 153 GHCVNTEGGFVCECGPGM-QLSADRHSCQDTDECLGTP-CQQRCKNSIGSYKCSCRTGFH 210
Query: 318 LRADGRSCRDIDECAGG-ARPCGGGQCRNTVGSYTCTCTDG 357
L + SC D++EC R C NTVGS+ CTC G
Sbjct: 211 LHGNRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCRPG 251
Score = 90.6 bits (215), Expect = 1e-17
Identities = 47/128 (36%), Positives = 63/128 (49%), Gaps = 9/128 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++EC C G C N GGF C+C PG + + H+C D +EC G C
Sbjct: 142 DIDECVT--SSC-EGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECL---GTPCQQRCK 195
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECAD--NDALCRGGRCVNTAGSFRCECGHGMEL 235
N+ GS+ C CR G+ CVD++EC +C C NT GSF C C G L
Sbjct: 196 NSIGSYKCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHHS-CHNTVGSFLCTCRPGFRL 254
Query: 236 APDRLSCK 243
DR+SC+
Sbjct: 255 RADRVSCE 262
Score = 71.7 bits (168), Expect = 6e-12
Identities = 54/168 (32%), Positives = 71/168 (42%), Gaps = 26/168 (15%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDD-ECELGTCD--CHPAADCINLPGSF 458
CG+G C I VC C DG EQG C + C CD C+ C +
Sbjct: 75 CGSGIC---IAPNVCSCQDG-----EQGATCPETHGPCGEYGCDLTCNHGG-CQEVARVC 125
Query: 459 QCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
G C D+DEC+T++ H C NT+G F C C G G++
Sbjct: 126 PVGFSMTEAAVGIRCTDIDECVTSSCEGH----CVNTEGGFVCEC-------GPGMQLSA 174
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+SC D DEC P C+ C N+ G Y+C C GF + SC+
Sbjct: 175 DRHSCQDTDECLGTP--CQQ-RCKNSIGSYKCSCRTGFHLHGNRHSCV 219
>AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein.
Length = 509
Score = 111 bits (268), Expect = 5e-24
Identities = 73/232 (31%), Positives = 103/232 (44%), Gaps = 31/232 (13%)
Query: 255 CSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCRE 314
C +G C +G +C C GYA T C+H C+NT GSY C C
Sbjct: 64 CKHGEC---IGPNKCKCHPGYAGKTCNQDLNECGLKPRP---CKHRCMNTYGSYKCYCLN 117
Query: 315 GWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDE 374
G+ L DG SC C+ C G C G C C + A + TC D+DE
Sbjct: 118 GYMLMPDG-SCSSALTCS--MANCQYG-CDVVKGQIRCQCPSPGLHLAPDGR-TCVDVDE 172
Query: 375 CADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGP-ACT 433
CA ++ P+ + C NT GS++C+C G+ + G C
Sbjct: 173 CAT-------------GRASCPRFRQ------CVNTFGSYICKCHKGFDLMYIGGKYQCH 213
Query: 434 DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGG 485
D DEC LG C A C N+ GS++C+C++G++GDG TC + + + G
Sbjct: 214 DIDECSLGQYQCSSFARCYNVRGSYKCKCKEGYQGDGLTCVYIPKVMIEPSG 265
Score = 106 bits (254), Expect = 2e-22
Identities = 68/212 (32%), Positives = 90/212 (42%), Gaps = 31/212 (14%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
C+ G C+ G +C+C G + +D++EC + C + C N G+Y+C C
Sbjct: 64 CKHGECI---GPNKCKCHPGYA---GKTCNQDLNECGLKPRPCKH-RCMNTYGSYKCYCL 116
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCRE-GWHLRADGRSCRDIDEC 331
GY + CQ+ C G C C G HL DGR+C D+DEC
Sbjct: 117 NGYM---LMPDGSCSSALTCSMANCQYGCDVVKGQIRCQCPSPGLHLAPDGRTCVDVDEC 173
Query: 332 AGGARPCGG-GQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
A G C QC NT GSY C C G G K C DIDEC S+ +
Sbjct: 174 ATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDEC----------SLGQY 223
Query: 391 QKSVDPQIPELCGAGSCHNTIGSFVCQCPDGY 422
Q S C+N GS+ C+C +GY
Sbjct: 224 QCS---------SFARCYNVRGSYKCKCKEGY 246
Score = 105 bits (251), Expect = 6e-22
Identities = 76/233 (32%), Positives = 102/233 (43%), Gaps = 47/233 (20%)
Query: 296 RCQHS-CVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGGQCRNTVGSYTCT 353
RC+H C+ G C C G+ G++C +D++EC RPC +C NT GSY C
Sbjct: 63 RCKHGECI---GPNKCKCHPGYA----GKTCNQDLNECGLKPRPCKH-RCMNTYGSYKCY 114
Query: 354 CTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGS 413
C +G + G+ C+ + T M + C G C G
Sbjct: 115 CLNGYMLMPDGS---------CSSAL-TCSMAN---------------CQYG-CDVVKGQ 148
Query: 414 FVCQCPD-GYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG----WRG 468
CQCP G + P+ G C D DEC G C C+N GS+ C+C G + G
Sbjct: 149 IRCQCPSPGLHLAPD-GRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIG 207
Query: 469 DGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
C D+DEC C A C N GS++C C GY+GDG + CVY
Sbjct: 208 GKYQCHDIDECSLGQYQCSSFARCYNVRGSYKCKCKEGYQGDG-----LTCVY 255
Score = 101 bits (242), Expect = 7e-21
Identities = 67/203 (33%), Positives = 87/203 (42%), Gaps = 19/203 (9%)
Query: 129 CGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCR 188
C HG C +G C C PGY + N D+NEC + C C NT GS+ C+C
Sbjct: 64 CKHGEC---IGPNKCKCHPGYAGKTCNQ---DLNECGLKPRPCKHR-CMNTYGSYKCYCL 116
Query: 189 PGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHGMELAPDRLSCKDIDE 247
GY C C+ A C+ G C G RC+C G+ LAPD +C D+DE
Sbjct: 117 NGYMLMPDGS-CSSALTCSM--ANCQYG-CDVVKGQIRCQCPSPGLHLAPDGRTCVDVDE 172
Query: 248 CSITSGICSN-GACENQMGTYQCVCDEG----YAQSTVKSHXXXXXXXXXXXXRCQHSCV 302
C+ C C N G+Y C C +G Y + H C
Sbjct: 173 CATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCY 232
Query: 303 NTPGSYHCTCREGWHLRADGRSC 325
N GSY C C+EG+ + DG +C
Sbjct: 233 NVRGSYKCKCKEGY--QGDGLTC 253
Score = 96.7 bits (230), Expect = 2e-19
Identities = 65/193 (33%), Positives = 85/193 (44%), Gaps = 17/193 (8%)
Query: 171 CGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECG 230
C G+C G C C PGY ++ D++EC C+ RC+NT GS++C C
Sbjct: 64 CKHGECI---GPNKCKCHPGYAGKTCNQ---DLNECGLKPRPCKH-RCMNTYGSYKCYCL 116
Query: 231 HGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDE-GYAQSTVKSHXXXXXX 289
+G L PD SC CS+ + C G C+ G +C C G +
Sbjct: 117 NGYMLMPDG-SCSSALTCSMAN--CQYG-CDVVKGQIRCQCPSPGLHLAPDGRTCVDVDE 172
Query: 290 XXXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRS--CRDIDECAGGARPCGG-GQCR 344
C CVNT GSY C C +G+ L G C DIDEC+ G C +C
Sbjct: 173 CATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCY 232
Query: 345 NTVGSYTCTCTDG 357
N GSY C C +G
Sbjct: 233 NVRGSYKCKCKEG 245
Score = 96.7 bits (230), Expect = 2e-19
Identities = 55/164 (33%), Positives = 74/164 (45%), Gaps = 17/164 (10%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRD-- 464
C NT GS+ C C +GY + P+ +C+ C + C C + G +C+C
Sbjct: 104 CMNTYGSYKCYCLNGYMLMPD--GSCSSALTCSMANCQ----YGCDVVKGQIRCQCPSPG 157
Query: 465 -GWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
DG TC DVDEC T C C NT GS+ C C G+ L + Y C
Sbjct: 158 LHLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICKCH-----KGFDLMYIGGKYQC 212
Query: 524 VDIDECANDPTLCEN-GHCSNTPGGYECDCDVGFTRAADGRSCL 566
DIDEC+ C + C N G Y+C C G+ DG +C+
Sbjct: 213 HDIDECSLGQYQCSSFARCYNVRGSYKCKCKEGY--QGDGLTCV 254
Score = 56.8 bits (131), Expect = 2e-07
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 4/89 (4%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD--SKNHTCVDVNECEIVDGVCGD 173
++V+ECA C R C N G + C C G++ + C D++EC + C
Sbjct: 168 VDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSS 227
Query: 174 -GDCHNTEGSFTCHCRPGYKADDFSKICV 201
C+N GS+ C C+ GY+ D + + +
Sbjct: 228 FARCYNVRGSYKCKCKEGYQGDGLTCVYI 256
Score = 41.1 bits (92), Expect = 0.010
Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 12/80 (15%)
Query: 486 CHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTP 545
C PR G +C C GY G C D++EC P C++ C NT
Sbjct: 60 CQPRCKHGECIGPNKCKCHPGYAG------KTC----NQDLNECGLKPRPCKH-RCMNTY 108
Query: 546 GGYECDCDVGFTRAADGRSC 565
G Y+C C G+ DG SC
Sbjct: 109 GSYKCYCLNGYMLMPDG-SC 127
>L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific
protein protein.
Length = 678
Score = 110 bits (265), Expect = 1e-23
Identities = 57/144 (39%), Positives = 73/144 (50%), Gaps = 10/144 (6%)
Query: 130 GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDCHNTEGSFTCHCR 188
G C++L+G F C C G+ C DVNEC +G C CHN GSF C C
Sbjct: 129 GTQACQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCH 183
Query: 189 PGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC 248
G++ + C DIDECAD++A C RC N GS+ C C G + +C+D+DEC
Sbjct: 184 SGFELSSDGRTCQDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC 242
Query: 249 SITSGICSNGACENQMGTYQCVCD 272
G C C N G+Y C CD
Sbjct: 243 --LQGRCEQ-VCVNSPGSYTCHCD 263
Score = 100 bits (239), Expect = 2e-20
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 6/117 (5%)
Query: 259 ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHL 318
AC++ MG + C+C G+ C C N PGS+HC+C G+ L
Sbjct: 132 ACQDLMGNFFCLCKAGWGGRLCDKDVNECSQENGG---CLQICHNKPGSFHCSCHSGFEL 188
Query: 319 RADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
+DGR+C+DIDECA + CG +C+N GSY+C C +G S+ + C+D+DEC
Sbjct: 189 SSDGRTCQDIDECA-DSEACGEARCKNLPGSYSCLCDEGFAYSS--QEKACRDVDEC 242
Score = 99 bits (238), Expect = 2e-20
Identities = 67/187 (35%), Positives = 88/187 (47%), Gaps = 40/187 (21%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL 358
+C + G++ C C+ GW GR C +D++EC+ C C N GS+ C+C G
Sbjct: 132 ACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGF 186
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
S+ G TCQDIDECAD E CG C N GS+ C C
Sbjct: 187 ELSSDGR--TCQDIDECAD---------------------SEACGEARCKNLPGSYSCLC 223
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGATC 473
+G++ Q AC D DEC G C+ C+N PGS+ C C DG G D TC
Sbjct: 224 DEGFAYS-SQEKACRDVDECLQGRCE----QVCVNSPGSYTCHC-DGRGGLKLSQDMDTC 277
Query: 474 EDVDECL 480
ED+ C+
Sbjct: 278 EDILPCV 284
Score = 99.1 bits (236), Expect = 4e-20
Identities = 53/131 (40%), Positives = 66/131 (50%), Gaps = 13/131 (9%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCAN 494
D+C CD C +L G+F C C+ GW G C+ DV+EC NGGC C N
Sbjct: 118 DQCTPNPCDRKGTQACQDLMGNFFCLCKAGW--GGRLCDKDVNECSQENGGC--LQICHN 173
Query: 495 TDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDV 554
GSF C C +G++ G RT C DIDECA D C C N PG Y C CD
Sbjct: 174 KPGSFHCSCHSGFELSSDG-RT------CQDIDECA-DSEACGEARCKNLPGSYSCLCDE 225
Query: 555 GFTRAADGRSC 565
GF ++ ++C
Sbjct: 226 GFAYSSQEKAC 236
Score = 97.9 bits (233), Expect = 8e-20
Identities = 68/210 (32%), Positives = 95/210 (45%), Gaps = 21/210 (10%)
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDI-DECADNDALCRGGR-CVNTAGSFRCECGHG 232
DC N GS P K F+ ++ D+C N +G + C + G+F C C G
Sbjct: 94 DCINKYGS------PYTKNSGFATCVQNLPDQCTPNPCDRKGTQACQDLMGNFFCLCKAG 147
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
RL KD++ECS +G C C N+ G++ C C G+ S+
Sbjct: 148 WG---GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECAD 203
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
+ C N PGSY C C EG+ + ++CRD+DEC G C C N+ GSYTC
Sbjct: 204 SEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR--C-EQVCVNSPGSYTC 260
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTI 382
C DG G QD+D C D++ +
Sbjct: 261 HC-DG-----RGGLKLSQDMDTCEDILPCV 284
Score = 95.9 bits (228), Expect = 3e-19
Identities = 60/170 (35%), Positives = 78/170 (45%), Gaps = 22/170 (12%)
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
V L P + G +C + +G+F C C G+ G C D +EC C
Sbjct: 113 VQNLPDQCTPNPCDRKGTQACQDLMGNFFCLCKAGWG-----GRLCDKDVNECSQENGGC 167
Query: 446 HPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N PGSF C C G+ DG TC+D+DEC ++ C A C N GS+ CLC
Sbjct: 168 LQI--CHNKPGSFHCSCHSGFELSSDGRTCQDIDEC-ADSEACG-EARCKNLPGSYSCLC 223
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD 553
D G+ Y + +C D+DEC CE C N+PG Y C CD
Sbjct: 224 DEGF---AYSSQEK----ACRDVDECLQGR--CEQV-CVNSPGSYTCHCD 263
Score = 81.0 bits (191), Expect = 1e-14
Identities = 49/125 (39%), Positives = 61/125 (48%), Gaps = 14/125 (11%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG- 465
CHN GSF C C G+ + + G C D DEC + A C NLPGS+ C C +G
Sbjct: 171 CHNKPGSFHCSCHSGFELSSD-GRTCQDIDEC--ADSEACGEARCKNLPGSYSCLCDEGF 227
Query: 466 -WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ C DVDECL G C C N+ GS+ C CD G G GL+ + +C
Sbjct: 228 AYSSQEKACRDVDECL--QGRC--EQVCVNSPGSYTCHCD----GRG-GLKLSQDMDTCE 278
Query: 525 DIDEC 529
DI C
Sbjct: 279 DILPC 283
Score = 69.7 bits (163), Expect = 3e-11
Identities = 36/91 (39%), Positives = 49/91 (53%), Gaps = 6/91 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++ECA CG RC+NL G ++C C G+ S+ C DV+EC + G C + C
Sbjct: 197 DIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC--LQGRC-EQVCV 252
Query: 178 NTEGSFTCHC--RPGYKADDFSKICVDIDEC 206
N+ GS+TCHC R G K C DI C
Sbjct: 253 NSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
>BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific 6
protein.
Length = 678
Score = 110 bits (265), Expect = 1e-23
Identities = 57/144 (39%), Positives = 73/144 (50%), Gaps = 10/144 (6%)
Query: 130 GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDCHNTEGSFTCHCR 188
G C++L+G F C C G+ C DVNEC +G C CHN GSF C C
Sbjct: 129 GTQACQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCH 183
Query: 189 PGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC 248
G++ + C DIDECAD++A C RC N GS+ C C G + +C+D+DEC
Sbjct: 184 SGFELSSDGRTCQDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC 242
Query: 249 SITSGICSNGACENQMGTYQCVCD 272
G C C N G+Y C CD
Sbjct: 243 --LQGRCEQ-VCVNSPGSYTCHCD 263
Score = 100 bits (239), Expect = 2e-20
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 6/117 (5%)
Query: 259 ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHL 318
AC++ MG + C+C G+ C C N PGS+HC+C G+ L
Sbjct: 132 ACQDLMGNFFCLCKAGWGGRLCDKDVNECSQENGG---CLQICHNKPGSFHCSCHSGFEL 188
Query: 319 RADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
+DGR+C+DIDECA + CG +C+N GSY+C C +G S+ + C+D+DEC
Sbjct: 189 SSDGRTCQDIDECA-DSEACGEARCKNLPGSYSCLCDEGFAYSS--QEKACRDVDEC 242
Score = 99 bits (238), Expect = 2e-20
Identities = 67/187 (35%), Positives = 88/187 (47%), Gaps = 40/187 (21%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL 358
+C + G++ C C+ GW GR C +D++EC+ C C N GS+ C+C G
Sbjct: 132 ACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGF 186
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
S+ G TCQDIDECAD E CG C N GS+ C C
Sbjct: 187 ELSSDGR--TCQDIDECAD---------------------SEACGEARCKNLPGSYSCLC 223
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGATC 473
+G++ Q AC D DEC G C+ C+N PGS+ C C DG G D TC
Sbjct: 224 DEGFAYS-SQEKACRDVDECLQGRCE----QVCVNSPGSYTCHC-DGRGGLKLSQDMDTC 277
Query: 474 EDVDECL 480
ED+ C+
Sbjct: 278 EDILPCV 284
Score = 99.1 bits (236), Expect = 4e-20
Identities = 53/131 (40%), Positives = 66/131 (50%), Gaps = 13/131 (9%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCAN 494
D+C CD C +L G+F C C+ GW G C+ DV+EC NGGC C N
Sbjct: 118 DQCTPNPCDRKGTQACQDLMGNFFCLCKAGW--GGRLCDKDVNECSQENGGC--LQICHN 173
Query: 495 TDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDV 554
GSF C C +G++ G RT C DIDECA D C C N PG Y C CD
Sbjct: 174 KPGSFHCSCHSGFELSSDG-RT------CQDIDECA-DSEACGEARCKNLPGSYSCLCDE 225
Query: 555 GFTRAADGRSC 565
GF ++ ++C
Sbjct: 226 GFAYSSQEKAC 236
Score = 97.9 bits (233), Expect = 8e-20
Identities = 68/210 (32%), Positives = 95/210 (45%), Gaps = 21/210 (10%)
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDI-DECADNDALCRGGR-CVNTAGSFRCECGHG 232
DC N GS P K F+ ++ D+C N +G + C + G+F C C G
Sbjct: 94 DCINKYGS------PYTKNSGFATCVQNLPDQCTPNPCDRKGTQACQDLMGNFFCLCKAG 147
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
RL KD++ECS +G C C N+ G++ C C G+ S+
Sbjct: 148 WG---GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECAD 203
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
+ C N PGSY C C EG+ + ++CRD+DEC G C C N+ GSYTC
Sbjct: 204 SEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR--C-EQVCVNSPGSYTC 260
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTI 382
C DG G QD+D C D++ +
Sbjct: 261 HC-DG-----RGGLKLSQDMDTCEDILPCV 284
Score = 95.9 bits (228), Expect = 3e-19
Identities = 60/170 (35%), Positives = 78/170 (45%), Gaps = 22/170 (12%)
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
V L P + G +C + +G+F C C G+ G C D +EC C
Sbjct: 113 VQNLPDQCTPNPCDRKGTQACQDLMGNFFCLCKAGWG-----GRLCDKDVNECSQENGGC 167
Query: 446 HPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N PGSF C C G+ DG TC+D+DEC ++ C A C N GS+ CLC
Sbjct: 168 LQI--CHNKPGSFHCSCHSGFELSSDGRTCQDIDEC-ADSEACG-EARCKNLPGSYSCLC 223
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD 553
D G+ Y + +C D+DEC CE C N+PG Y C CD
Sbjct: 224 DEGF---AYSSQEK----ACRDVDECLQGR--CEQV-CVNSPGSYTCHCD 263
Score = 81.0 bits (191), Expect = 1e-14
Identities = 49/125 (39%), Positives = 61/125 (48%), Gaps = 14/125 (11%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG- 465
CHN GSF C C G+ + + G C D DEC + A C NLPGS+ C C +G
Sbjct: 171 CHNKPGSFHCSCHSGFELSSD-GRTCQDIDEC--ADSEACGEARCKNLPGSYSCLCDEGF 227
Query: 466 -WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ C DVDECL G C C N+ GS+ C CD G G GL+ + +C
Sbjct: 228 AYSSQEKACRDVDECL--QGRC--EQVCVNSPGSYTCHCD----GRG-GLKLSQDMDTCE 278
Query: 525 DIDEC 529
DI C
Sbjct: 279 DILPC 283
Score = 69.7 bits (163), Expect = 3e-11
Identities = 36/91 (39%), Positives = 49/91 (53%), Gaps = 6/91 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++ECA CG RC+NL G ++C C G+ S+ C DV+EC + G C + C
Sbjct: 197 DIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC--LQGRC-EQVCV 252
Query: 178 NTEGSFTCHC--RPGYKADDFSKICVDIDEC 206
N+ GS+TCHC R G K C DI C
Sbjct: 253 NSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
>BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific 6
protein.
Length = 678
Score = 110 bits (265), Expect = 1e-23
Identities = 57/144 (39%), Positives = 73/144 (50%), Gaps = 10/144 (6%)
Query: 130 GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDCHNTEGSFTCHCR 188
G C++L+G F C C G+ C DVNEC +G C CHN GSF C C
Sbjct: 129 GTQACQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCH 183
Query: 189 PGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC 248
G++ + C DIDECAD++A C RC N GS+ C C G + +C+D+DEC
Sbjct: 184 SGFELSSDGRTCQDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC 242
Query: 249 SITSGICSNGACENQMGTYQCVCD 272
G C C N G+Y C CD
Sbjct: 243 --LQGRCEQ-VCVNSPGSYTCHCD 263
Score = 100 bits (239), Expect = 2e-20
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 6/117 (5%)
Query: 259 ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHL 318
AC++ MG + C+C G+ C C N PGS+HC+C G+ L
Sbjct: 132 ACQDLMGNFFCLCKAGWGGRLCDKDVNECSQENGG---CLQICHNKPGSFHCSCHSGFEL 188
Query: 319 RADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
+DGR+C+DIDECA + CG +C+N GSY+C C +G S+ + C+D+DEC
Sbjct: 189 SSDGRTCQDIDECA-DSEACGEARCKNLPGSYSCLCDEGFAYSS--QEKACRDVDEC 242
Score = 99 bits (238), Expect = 2e-20
Identities = 67/187 (35%), Positives = 88/187 (47%), Gaps = 40/187 (21%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL 358
+C + G++ C C+ GW GR C +D++EC+ C C N GS+ C+C G
Sbjct: 132 ACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGF 186
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
S+ G TCQDIDECAD E CG C N GS+ C C
Sbjct: 187 ELSSDGR--TCQDIDECAD---------------------SEACGEARCKNLPGSYSCLC 223
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGATC 473
+G++ Q AC D DEC G C+ C+N PGS+ C C DG G D TC
Sbjct: 224 DEGFAYS-SQEKACRDVDECLQGRCE----QVCVNSPGSYTCHC-DGRGGLKLSQDMDTC 277
Query: 474 EDVDECL 480
ED+ C+
Sbjct: 278 EDILPCV 284
Score = 99.1 bits (236), Expect = 4e-20
Identities = 53/131 (40%), Positives = 66/131 (50%), Gaps = 13/131 (9%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCAN 494
D+C CD C +L G+F C C+ GW G C+ DV+EC NGGC C N
Sbjct: 118 DQCTPNPCDRKGTQACQDLMGNFFCLCKAGW--GGRLCDKDVNECSQENGGC--LQICHN 173
Query: 495 TDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDV 554
GSF C C +G++ G RT C DIDECA D C C N PG Y C CD
Sbjct: 174 KPGSFHCSCHSGFELSSDG-RT------CQDIDECA-DSEACGEARCKNLPGSYSCLCDE 225
Query: 555 GFTRAADGRSC 565
GF ++ ++C
Sbjct: 226 GFAYSSQEKAC 236
Score = 97.9 bits (233), Expect = 8e-20
Identities = 68/210 (32%), Positives = 95/210 (45%), Gaps = 21/210 (10%)
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDI-DECADNDALCRGGR-CVNTAGSFRCECGHG 232
DC N GS P K F+ ++ D+C N +G + C + G+F C C G
Sbjct: 94 DCINKYGS------PYTKNSGFATCVQNLPDQCTPNPCDRKGTQACQDLMGNFFCLCKAG 147
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
RL KD++ECS +G C C N+ G++ C C G+ S+
Sbjct: 148 WG---GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECAD 203
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
+ C N PGSY C C EG+ + ++CRD+DEC G C C N+ GSYTC
Sbjct: 204 SEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR--C-EQVCVNSPGSYTC 260
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTI 382
C DG G QD+D C D++ +
Sbjct: 261 HC-DG-----RGGLKLSQDMDTCEDILPCV 284
Score = 95.9 bits (228), Expect = 3e-19
Identities = 60/170 (35%), Positives = 78/170 (45%), Gaps = 22/170 (12%)
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
V L P + G +C + +G+F C C G+ G C D +EC C
Sbjct: 113 VQNLPDQCTPNPCDRKGTQACQDLMGNFFCLCKAGWG-----GRLCDKDVNECSQENGGC 167
Query: 446 HPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N PGSF C C G+ DG TC+D+DEC ++ C A C N GS+ CLC
Sbjct: 168 LQI--CHNKPGSFHCSCHSGFELSSDGRTCQDIDEC-ADSEACG-EARCKNLPGSYSCLC 223
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD 553
D G+ Y + +C D+DEC CE C N+PG Y C CD
Sbjct: 224 DEGF---AYSSQEK----ACRDVDECLQGR--CEQV-CVNSPGSYTCHCD 263
Score = 81.0 bits (191), Expect = 1e-14
Identities = 49/125 (39%), Positives = 61/125 (48%), Gaps = 14/125 (11%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG- 465
CHN GSF C C G+ + + G C D DEC + A C NLPGS+ C C +G
Sbjct: 171 CHNKPGSFHCSCHSGFELSSD-GRTCQDIDEC--ADSEACGEARCKNLPGSYSCLCDEGF 227
Query: 466 -WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ C DVDECL G C C N+ GS+ C CD G G GL+ + +C
Sbjct: 228 AYSSQEKACRDVDECL--QGRC--EQVCVNSPGSYTCHCD----GRG-GLKLSQDMDTCE 278
Query: 525 DIDEC 529
DI C
Sbjct: 279 DILPC 283
Score = 69.7 bits (163), Expect = 3e-11
Identities = 36/91 (39%), Positives = 49/91 (53%), Gaps = 6/91 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++ECA CG RC+NL G ++C C G+ S+ C DV+EC + G C + C
Sbjct: 197 DIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC--LQGRC-EQVCV 252
Query: 178 NTEGSFTCHC--RPGYKADDFSKICVDIDEC 206
N+ GS+TCHC R G K C DI C
Sbjct: 253 NSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
>AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specific 6
protein.
Length = 678
Score = 110 bits (265), Expect = 1e-23
Identities = 57/144 (39%), Positives = 73/144 (50%), Gaps = 10/144 (6%)
Query: 130 GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDCHNTEGSFTCHCR 188
G C++L+G F C C G+ C DVNEC +G C CHN GSF C C
Sbjct: 129 GTQACQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCH 183
Query: 189 PGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC 248
G++ + C DIDECAD++A C RC N GS+ C C G + +C+D+DEC
Sbjct: 184 SGFELSSDGRTCQDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC 242
Query: 249 SITSGICSNGACENQMGTYQCVCD 272
G C C N G+Y C CD
Sbjct: 243 --LQGRCEQ-VCVNSPGSYTCHCD 263
Score = 100 bits (239), Expect = 2e-20
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 6/117 (5%)
Query: 259 ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHL 318
AC++ MG + C+C G+ C C N PGS+HC+C G+ L
Sbjct: 132 ACQDLMGNFFCLCKAGWGGRLCDKDVNECSQENGG---CLQICHNKPGSFHCSCHSGFEL 188
Query: 319 RADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
+DGR+C+DIDECA + CG +C+N GSY+C C +G S+ + C+D+DEC
Sbjct: 189 SSDGRTCQDIDECA-DSEACGEARCKNLPGSYSCLCDEGFAYSS--QEKACRDVDEC 242
Score = 99 bits (238), Expect = 2e-20
Identities = 67/187 (35%), Positives = 88/187 (47%), Gaps = 40/187 (21%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL 358
+C + G++ C C+ GW GR C +D++EC+ C C N GS+ C+C G
Sbjct: 132 ACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGF 186
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
S+ G TCQDIDECAD E CG C N GS+ C C
Sbjct: 187 ELSSDGR--TCQDIDECAD---------------------SEACGEARCKNLPGSYSCLC 223
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGATC 473
+G++ Q AC D DEC G C+ C+N PGS+ C C DG G D TC
Sbjct: 224 DEGFAYS-SQEKACRDVDECLQGRCE----QVCVNSPGSYTCHC-DGRGGLKLSQDMDTC 277
Query: 474 EDVDECL 480
ED+ C+
Sbjct: 278 EDILPCV 284
Score = 99.1 bits (236), Expect = 4e-20
Identities = 53/131 (40%), Positives = 66/131 (50%), Gaps = 13/131 (9%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCAN 494
D+C CD C +L G+F C C+ GW G C+ DV+EC NGGC C N
Sbjct: 118 DQCTPNPCDRKGTQACQDLMGNFFCLCKAGW--GGRLCDKDVNECSQENGGC--LQICHN 173
Query: 495 TDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDV 554
GSF C C +G++ G RT C DIDECA D C C N PG Y C CD
Sbjct: 174 KPGSFHCSCHSGFELSSDG-RT------CQDIDECA-DSEACGEARCKNLPGSYSCLCDE 225
Query: 555 GFTRAADGRSC 565
GF ++ ++C
Sbjct: 226 GFAYSSQEKAC 236
Score = 97.9 bits (233), Expect = 8e-20
Identities = 68/210 (32%), Positives = 95/210 (45%), Gaps = 21/210 (10%)
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDI-DECADNDALCRGGR-CVNTAGSFRCECGHG 232
DC N GS P K F+ ++ D+C N +G + C + G+F C C G
Sbjct: 94 DCINKYGS------PYTKNSGFATCVQNLPDQCTPNPCDRKGTQACQDLMGNFFCLCKAG 147
Query: 233 MELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXX 292
RL KD++ECS +G C C N+ G++ C C G+ S+
Sbjct: 148 WG---GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECAD 203
Query: 293 XXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTC 352
+ C N PGSY C C EG+ + ++CRD+DEC G C C N+ GSYTC
Sbjct: 204 SEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR--C-EQVCVNSPGSYTC 260
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTI 382
C DG G QD+D C D++ +
Sbjct: 261 HC-DG-----RGGLKLSQDMDTCEDILPCV 284
Score = 95.9 bits (228), Expect = 3e-19
Identities = 60/170 (35%), Positives = 78/170 (45%), Gaps = 22/170 (12%)
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
V L P + G +C + +G+F C C G+ G C D +EC C
Sbjct: 113 VQNLPDQCTPNPCDRKGTQACQDLMGNFFCLCKAGWG-----GRLCDKDVNECSQENGGC 167
Query: 446 HPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N PGSF C C G+ DG TC+D+DEC ++ C A C N GS+ CLC
Sbjct: 168 LQI--CHNKPGSFHCSCHSGFELSSDGRTCQDIDEC-ADSEACG-EARCKNLPGSYSCLC 223
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD 553
D G+ Y + +C D+DEC CE C N+PG Y C CD
Sbjct: 224 DEGF---AYSSQEK----ACRDVDECLQGR--CEQV-CVNSPGSYTCHCD 263
Score = 81.0 bits (191), Expect = 1e-14
Identities = 49/125 (39%), Positives = 61/125 (48%), Gaps = 14/125 (11%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG- 465
CHN GSF C C G+ + + G C D DEC + A C NLPGS+ C C +G
Sbjct: 171 CHNKPGSFHCSCHSGFELSSD-GRTCQDIDEC--ADSEACGEARCKNLPGSYSCLCDEGF 227
Query: 466 -WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ C DVDECL G C C N+ GS+ C CD G G GL+ + +C
Sbjct: 228 AYSSQEKACRDVDECL--QGRC--EQVCVNSPGSYTCHCD----GRG-GLKLSQDMDTCE 278
Query: 525 DIDEC 529
DI C
Sbjct: 279 DILPC 283
Score = 69.7 bits (163), Expect = 3e-11
Identities = 36/91 (39%), Positives = 49/91 (53%), Gaps = 6/91 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++ECA CG RC+NL G ++C C G+ S+ C DV+EC + G C + C
Sbjct: 197 DIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC--LQGRC-EQVCV 252
Query: 178 NTEGSFTCHC--RPGYKADDFSKICVDIDEC 206
N+ GS+TCHC R G K C DI C
Sbjct: 253 NSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
>AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens
cDNA FLJ44569 fis, clone UTERU3009979, highly similar
to Homo sapiens growth arrest-specific 6 (GAS6). ).
Length = 624
Score = 110 bits (265), Expect = 1e-23
Identities = 57/144 (39%), Positives = 73/144 (50%), Gaps = 10/144 (6%)
Query: 130 GHGRCRNLLGGFTCDCFPGYEKDSKNHTC-VDVNECEIVDGVCGDGDCHNTEGSFTCHCR 188
G C++L+G F C C G+ C DVNEC +G C CHN GSF C C
Sbjct: 75 GTQACQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCH 129
Query: 189 PGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDEC 248
G++ + C DIDECAD++A C RC N GS+ C C G + +C+D+DEC
Sbjct: 130 SGFELSSDGRTCQDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC 188
Query: 249 SITSGICSNGACENQMGTYQCVCD 272
G C C N G+Y C CD
Sbjct: 189 --LQGRCEQ-VCVNSPGSYTCHCD 209
Score = 100 bits (239), Expect = 2e-20
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 6/117 (5%)
Query: 259 ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHL 318
AC++ MG + C+C G+ C C N PGS+HC+C G+ L
Sbjct: 78 ACQDLMGNFFCLCKAGWGGRLCDKDVNECSQENGG---CLQICHNKPGSFHCSCHSGFEL 134
Query: 319 RADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDEC 375
+DGR+C+DIDECA + CG +C+N GSY+C C +G S+ + C+D+DEC
Sbjct: 135 SSDGRTCQDIDECA-DSEACGEARCKNLPGSYSCLCDEGFAYSS--QEKACRDVDEC 188
Score = 99 bits (238), Expect = 2e-20
Identities = 67/187 (35%), Positives = 88/187 (47%), Gaps = 40/187 (21%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGGQCRNTVGSYTCTCTDGL 358
+C + G++ C C+ GW GR C +D++EC+ C C N GS+ C+C G
Sbjct: 78 ACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGF 132
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
S+ G TCQDIDECAD E CG C N GS+ C C
Sbjct: 133 ELSSDGR--TCQDIDECAD---------------------SEACGEARCKNLPGSYSCLC 169
Query: 419 PDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRG-----DGATC 473
+G++ Q AC D DEC G C+ C+N PGS+ C C DG G D TC
Sbjct: 170 DEGFAYS-SQEKACRDVDECLQGRCE----QVCVNSPGSYTCHC-DGRGGLKLSQDMDTC 223
Query: 474 EDVDECL 480
ED+ C+
Sbjct: 224 EDILPCV 230
Score = 99.1 bits (236), Expect = 4e-20
Identities = 53/131 (40%), Positives = 66/131 (50%), Gaps = 13/131 (9%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCAN 494
D+C CD C +L G+F C C+ GW G C+ DV+EC NGGC C N
Sbjct: 64 DQCTPNPCDRKGTQACQDLMGNFFCLCKAGW--GGRLCDKDVNECSQENGGC--LQICHN 119
Query: 495 TDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDV 554
GSF C C +G++ G RT C DIDECA D C C N PG Y C CD
Sbjct: 120 KPGSFHCSCHSGFELSSDG-RT------CQDIDECA-DSEACGEARCKNLPGSYSCLCDE 171
Query: 555 GFTRAADGRSC 565
GF ++ ++C
Sbjct: 172 GFAYSSQEKAC 182
Score = 97.1 bits (231), Expect = 1e-19
Identities = 60/180 (33%), Positives = 84/180 (46%), Gaps = 14/180 (7%)
Query: 204 DECADNDALCRGGR-CVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACEN 262
D+C N +G + C + G+F C C G RL KD++ECS +G C C N
Sbjct: 64 DQCTPNPCDRKGTQACQDLMGNFFCLCKAGWG---GRLCDKDVNECSQENGGCLQ-ICHN 119
Query: 263 QMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADG 322
+ G++ C C G+ S+ + C N PGSY C C EG+ +
Sbjct: 120 KPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQE 179
Query: 323 RSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTI 382
++CRD+DEC G C C N+ GSYTC C DG G QD+D C D++ +
Sbjct: 180 KACRDVDECLQGR--C-EQVCVNSPGSYTCHC-DG-----RGGLKLSQDMDTCEDILPCV 230
Score = 95.9 bits (228), Expect = 3e-19
Identities = 60/170 (35%), Positives = 78/170 (45%), Gaps = 22/170 (12%)
Query: 387 VDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
V L P + G +C + +G+F C C G+ G C D +EC C
Sbjct: 59 VQNLPDQCTPNPCDRKGTQACQDLMGNFFCLCKAGWG-----GRLCDKDVNECSQENGGC 113
Query: 446 HPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C N PGSF C C G+ DG TC+D+DEC ++ C A C N GS+ CLC
Sbjct: 114 LQI--CHNKPGSFHCSCHSGFELSSDGRTCQDIDEC-ADSEACG-EARCKNLPGSYSCLC 169
Query: 504 DTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD 553
D G+ Y + +C D+DEC CE C N+PG Y C CD
Sbjct: 170 DEGF---AYSSQEK----ACRDVDECLQGR--CEQV-CVNSPGSYTCHCD 209
Score = 81.0 bits (191), Expect = 1e-14
Identities = 49/125 (39%), Positives = 61/125 (48%), Gaps = 14/125 (11%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG- 465
CHN GSF C C G+ + + G C D DEC + A C NLPGS+ C C +G
Sbjct: 117 CHNKPGSFHCSCHSGFELSSD-GRTCQDIDEC--ADSEACGEARCKNLPGSYSCLCDEGF 173
Query: 466 -WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ C DVDECL G C C N+ GS+ C CD G G GL+ + +C
Sbjct: 174 AYSSQEKACRDVDECL--QGRC--EQVCVNSPGSYTCHCD----GRG-GLKLSQDMDTCE 224
Query: 525 DIDEC 529
DI C
Sbjct: 225 DILPC 229
Score = 69.7 bits (163), Expect = 3e-11
Identities = 36/91 (39%), Positives = 49/91 (53%), Gaps = 6/91 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+++ECA CG RC+NL G ++C C G+ S+ C DV+EC + G C + C
Sbjct: 143 DIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC--LQGRC-EQVCV 198
Query: 178 NTEGSFTCHC--RPGYKADDFSKICVDIDEC 206
N+ GS+TCHC R G K C DI C
Sbjct: 199 NSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 229
>X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for
kidney epidermal growth factor (EGF) precursor. ).
Length = 1207
Score = 109 bits (262), Expect = 3e-23
Identities = 70/211 (33%), Positives = 102/211 (48%), Gaps = 26/211 (12%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQC--RNTVGSYTCTC 354
C+H C G+ C+CREG+ +DG++C +D G + GG+ +N V T
Sbjct: 752 CEHICKKRLGTAWCSCREGFMKASDGKTCLALD----GHQLLAGGEVDLKNQV-----TP 802
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGS 413
D L + +I E ++ IM+S D+ D P C C +
Sbjct: 803 LDILSKTRVSE----DNITESQHMLVAEIMVS-DQ-----DDCAPVGCSMYARCISEGED 852
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD-CINLPGSFQCRCRDGWRGDGAT 472
CQC G++ G C+D DECE+G C PA+ CIN G + CRC +G++GDG
Sbjct: 853 ATCQCLKGFA---GDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIH 909
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C D+DEC C A+C NT+G + C+C
Sbjct: 910 CLDIDECQLGVHSCGENASCTNTEGGYTCMC 940
Score = 93.1 bits (221), Expect = 2e-18
Identities = 48/122 (39%), Positives = 62/122 (50%), Gaps = 13/122 (10%)
Query: 433 TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRAT- 491
+D D+C C + A CI+ C+C G+ GDG C D+DEC C P ++
Sbjct: 830 SDQDDCAPVGCSMY--ARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSK 887
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYEC 550
C NT+G + C C GY+GDG C+DIDEC C EN C+NT GGY C
Sbjct: 888 CINTEGGYVCRCSEGYQGDG---------IHCLDIDECQLGVHSCGENASCTNTEGGYTC 938
Query: 551 DC 552
C
Sbjct: 939 MC 940
Score = 77.8 bits (183), Expect = 1e-13
Identities = 49/163 (30%), Positives = 63/163 (38%), Gaps = 5/163 (3%)
Query: 164 CEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAG 223
C++ G C C S C C GY K C D++ECA + C G C NT G
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPG 376
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSH 283
S+ C C G L PD C + C CS+ G C C EG +
Sbjct: 377 SYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL-CFCPEGSVLE--RDG 433
Query: 284 XXXXXXXXXXXXRCQHSCVN-TPGSYHCTCREGWHLRADGRSC 325
C CV +P S+ C C G+ L+ D +SC
Sbjct: 434 KTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSC 476
Score = 77.0 bits (181), Expect = 2e-13
Identities = 45/128 (35%), Positives = 58/128 (45%), Gaps = 10/128 (7%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC--GDGDCH 177
++CA G + RC + TC C G+ D K C D++ECE+ VC C
Sbjct: 833 DDCAPV-GCSMYARCISEGEDATCQCLKGFAGDGK--LCSDIDECEMGVPVCPPASSKCI 889
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELA 236
NTEG + C C GY+ D C+DIDEC C C NT G + C C L+
Sbjct: 890 NTEGGYVCRCSEGYQGDGIH--CLDIDECQLGVHSCGENASCTNTEGGYTCMCAG--RLS 945
Query: 237 PDRLSCKD 244
L C D
Sbjct: 946 EPGLICPD 953
Score = 75.4 bits (177), Expect = 5e-13
Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 1/112 (0%)
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
C + G CS+ C + ++ C+C EGYA S + + C C NTPGS
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPGS 377
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
Y+CTC G+ L DG+ C + C C C T C C +G V
Sbjct: 378 YYCTCPVGFVLLPDGKRCHQLVSCPRNVSEC-SHDCVLTSEGPLCFCPEGSV 428
Score = 70.1 bits (164), Expect = 2e-11
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 11/149 (7%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
C C S C C G L+ DR C+D++EC+ + C+ G C+N G+Y C C
Sbjct: 325 CSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPGSYYCTCP 383
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECA 332
G+ C H CV T C C EG L DG++ C+
Sbjct: 384 VGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKT------CS 437
Query: 333 GGARPCGGGQCRNTVG----SYTCTCTDG 357
G + P GG + V S+ C C G
Sbjct: 438 GCSSPDNGGCSQLCVPLSPVSWECDCFPG 466
Score = 69.7 bits (163), Expect = 3e-11
Identities = 58/217 (26%), Positives = 81/217 (37%), Gaps = 19/217 (8%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C G C H C+ LG C C G+ K S TC+ ++ +++ G G+ D N
Sbjct: 745 CLYQNGGCEH-ICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAG--GEVDLKNQVT 801
Query: 182 SFTCHCRPGYKADDFSK---------ICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
+ D+ ++ + D D+CA RC++ C+C G
Sbjct: 802 PLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAP-VGCSMYARCISEGEDATCQCLKG 860
Query: 233 MELAPDRLSCKDIDECSITSGIC--SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
A D C DIDEC + +C ++ C N G Y C C EGY +
Sbjct: 861 --FAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQL 918
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRD 327
SC NT G Y C C L G C D
Sbjct: 919 GVHSCGENASCTNTEGGYTCMC--AGRLSEPGLICPD 953
Score = 66.9 bits (156), Expect = 2e-10
Identities = 47/154 (30%), Positives = 58/154 (37%), Gaps = 4/154 (2%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C G C C L C C GY C DVNEC + C G C NT G
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPG 376
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
S+ C C G+ K C + C N + C CV T+ C C G L D +
Sbjct: 377 SYYCTCPVGFVLLPDGKRCHQLVSCPRNVSEC-SHDCVLTSEGPLCFCPEGSVLERDGKT 435
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C S +G CS +++C C GY
Sbjct: 436 CSGCS--SPDNGGCSQLCVPLSPVSWECDCFPGY 467
Score = 63.3 bits (147), Expect = 2e-09
Identities = 47/166 (28%), Positives = 65/166 (39%), Gaps = 16/166 (9%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR 461
C + C + S +C C +GY++ ++ C D +EC C C N PGS+ C
Sbjct: 325 CSSTVCGQDLQSHLCMCAEGYALSRDR-KYCEDVNECAFWNHGC--TLGCKNTPGSYYCT 381
Query: 462 CRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C G+ DG C + C N C C T C C G + G C
Sbjct: 382 CPVGFVLLPDGKRCHQLVSCPRNVSECSH--DCVLTSEGPLCFCPEGSVLERDG--KTCS 437
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
S D C+ LC +P +ECDC G+ D +SC
Sbjct: 438 GCSSPDNGGCSQ---LC----VPLSPVSWECDCFPGYDLQLDEKSC 476
Score = 56.0 bits (129), Expect = 3e-07
Identities = 42/132 (31%), Positives = 55/132 (41%), Gaps = 13/132 (9%)
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANT 495
C+L +C C S C C +G+ D CEDV+EC N GC C NT
Sbjct: 318 CKLRKGNCSSTV-CGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGC--TLGCKNT 374
Query: 496 DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
GS+ C C G+ G R V ++ EC++D C T G C C G
Sbjct: 375 PGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHD--------CVLTSEGPLCFCPEG 426
Query: 556 FTRAADGRSCLG 567
DG++C G
Sbjct: 427 SVLERDGKTCSG 438
Score = 50.0 bits (114), Expect = 2e-05
Identities = 33/94 (35%), Positives = 39/94 (41%), Gaps = 15/94 (15%)
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D D+C GC A C + C C G+ GDG C DIDEC
Sbjct: 831 DQDDCAPV--GCSMYARCISEGEDATCQCLKGFAGDGK---------LCSDIDECEMGVP 879
Query: 535 LCE--NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C + C NT GGY C C G+ DG CL
Sbjct: 880 VCPPASSKCINTEGGYVCRCSEGY--QGDGIHCL 911
Score = 33.9 bits (74), Expect = 1.5
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 4/39 (10%)
Query: 532 DPTLCENGHCSNTP----GGYECDCDVGFTRAADGRSCL 566
DP L +NG C + G C C GF +A+DG++CL
Sbjct: 743 DPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCL 781
>BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor
(beta-urogastrone) protein.
Length = 1207
Score = 109 bits (262), Expect = 3e-23
Identities = 70/211 (33%), Positives = 102/211 (48%), Gaps = 26/211 (12%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQC--RNTVGSYTCTC 354
C+H C G+ C+CREG+ +DG++C +D G + GG+ +N V T
Sbjct: 752 CEHICKKRLGTAWCSCREGFMKASDGKTCLALD----GHQLLAGGEVDLKNQV-----TP 802
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGS 413
D L + +I E ++ IM+S D+ D P C C +
Sbjct: 803 LDILSKTRVSE----DNITESQHMLVAEIMVS-DQ-----DDCAPVGCSMYARCISEGED 852
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD-CINLPGSFQCRCRDGWRGDGAT 472
CQC G++ G C+D DECE+G C PA+ CIN G + CRC +G++GDG
Sbjct: 853 ATCQCLKGFA---GDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIH 909
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C D+DEC C A+C NT+G + C+C
Sbjct: 910 CLDIDECQLGVHSCGENASCTNTEGGYTCMC 940
Score = 93.1 bits (221), Expect = 2e-18
Identities = 48/122 (39%), Positives = 62/122 (50%), Gaps = 13/122 (10%)
Query: 433 TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRAT- 491
+D D+C C + A CI+ C+C G+ GDG C D+DEC C P ++
Sbjct: 830 SDQDDCAPVGCSMY--ARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSK 887
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYEC 550
C NT+G + C C GY+GDG C+DIDEC C EN C+NT GGY C
Sbjct: 888 CINTEGGYVCRCSEGYQGDG---------IHCLDIDECQLGVHSCGENASCTNTEGGYTC 938
Query: 551 DC 552
C
Sbjct: 939 MC 940
Score = 77.8 bits (183), Expect = 1e-13
Identities = 49/163 (30%), Positives = 63/163 (38%), Gaps = 5/163 (3%)
Query: 164 CEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAG 223
C++ G C C S C C GY K C D++ECA + C G C NT G
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPG 376
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSH 283
S+ C C G L PD C + C CS+ G C C EG +
Sbjct: 377 SYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL-CFCPEGSVLE--RDG 433
Query: 284 XXXXXXXXXXXXRCQHSCVN-TPGSYHCTCREGWHLRADGRSC 325
C CV +P S+ C C G+ L+ D +SC
Sbjct: 434 KTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSC 476
Score = 77.0 bits (181), Expect = 2e-13
Identities = 45/128 (35%), Positives = 58/128 (45%), Gaps = 10/128 (7%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC--GDGDCH 177
++CA G + RC + TC C G+ D K C D++ECE+ VC C
Sbjct: 833 DDCAPV-GCSMYARCISEGEDATCQCLKGFAGDGK--LCSDIDECEMGVPVCPPASSKCI 889
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELA 236
NTEG + C C GY+ D C+DIDEC C C NT G + C C L+
Sbjct: 890 NTEGGYVCRCSEGYQGDGIH--CLDIDECQLGVHSCGENASCTNTEGGYTCMCAG--RLS 945
Query: 237 PDRLSCKD 244
L C D
Sbjct: 946 EPGLICPD 953
Score = 75.4 bits (177), Expect = 5e-13
Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 1/112 (0%)
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
C + G CS+ C + ++ C+C EGYA S + + C C NTPGS
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPGS 377
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
Y+CTC G+ L DG+ C + C C C T C C +G V
Sbjct: 378 YYCTCPVGFVLLPDGKRCHQLVSCPRNVSEC-SHDCVLTSEGPLCFCPEGSV 428
Score = 70.1 bits (164), Expect = 2e-11
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 11/149 (7%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
C C S C C G L+ DR C+D++EC+ + C+ G C+N G+Y C C
Sbjct: 325 CSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPGSYYCTCP 383
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECA 332
G+ C H CV T C C EG L DG++ C+
Sbjct: 384 VGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKT------CS 437
Query: 333 GGARPCGGGQCRNTVG----SYTCTCTDG 357
G + P GG + V S+ C C G
Sbjct: 438 GCSSPDNGGCSQLCVPLSPVSWECDCFPG 466
Score = 69.7 bits (163), Expect = 3e-11
Identities = 58/217 (26%), Positives = 81/217 (37%), Gaps = 19/217 (8%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C G C H C+ LG C C G+ K S TC+ ++ +++ G G+ D N
Sbjct: 745 CLYQNGGCEH-ICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAG--GEVDLKNQVT 801
Query: 182 SFTCHCRPGYKADDFSK---------ICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
+ D+ ++ + D D+CA RC++ C+C G
Sbjct: 802 PLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAP-VGCSMYARCISEGEDATCQCLKG 860
Query: 233 MELAPDRLSCKDIDECSITSGIC--SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
A D C DIDEC + +C ++ C N G Y C C EGY +
Sbjct: 861 --FAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQL 918
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRD 327
SC NT G Y C C L G C D
Sbjct: 919 GVHSCGENASCTNTEGGYTCMC--AGRLSEPGLICPD 953
Score = 66.9 bits (156), Expect = 2e-10
Identities = 47/154 (30%), Positives = 58/154 (37%), Gaps = 4/154 (2%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C G C C L C C GY C DVNEC + C G C NT G
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPG 376
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
S+ C C G+ K C + C N + C CV T+ C C G L D +
Sbjct: 377 SYYCTCPVGFVLLPDGKRCHQLVSCPRNVSEC-SHDCVLTSEGPLCFCPEGSVLERDGKT 435
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C S +G CS +++C C GY
Sbjct: 436 CSGCS--SPDNGGCSQLCVPLSPVSWECDCFPGY 467
Score = 63.3 bits (147), Expect = 2e-09
Identities = 47/166 (28%), Positives = 65/166 (39%), Gaps = 16/166 (9%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR 461
C + C + S +C C +GY++ ++ C D +EC C C N PGS+ C
Sbjct: 325 CSSTVCGQDLQSHLCMCAEGYALSRDR-KYCEDVNECAFWNHGC--TLGCKNTPGSYYCT 381
Query: 462 CRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C G+ DG C + C N C C T C C G + G C
Sbjct: 382 CPVGFVLLPDGKRCHQLVSCPRNVSECSH--DCVLTSEGPLCFCPEGSVLERDG--KTCS 437
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
S D C+ LC +P +ECDC G+ D +SC
Sbjct: 438 GCSSPDNGGCSQ---LC----VPLSPVSWECDCFPGYDLQLDEKSC 476
Score = 56.0 bits (129), Expect = 3e-07
Identities = 42/132 (31%), Positives = 55/132 (41%), Gaps = 13/132 (9%)
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANT 495
C+L +C C S C C +G+ D CEDV+EC N GC C NT
Sbjct: 318 CKLRKGNCSSTV-CGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGC--TLGCKNT 374
Query: 496 DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
GS+ C C G+ G R V ++ EC++D C T G C C G
Sbjct: 375 PGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHD--------CVLTSEGPLCFCPEG 426
Query: 556 FTRAADGRSCLG 567
DG++C G
Sbjct: 427 SVLERDGKTCSG 438
Score = 50.0 bits (114), Expect = 2e-05
Identities = 33/94 (35%), Positives = 39/94 (41%), Gaps = 15/94 (15%)
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D D+C GC A C + C C G+ GDG C DIDEC
Sbjct: 831 DQDDCAPV--GCSMYARCISEGEDATCQCLKGFAGDGK---------LCSDIDECEMGVP 879
Query: 535 LCE--NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C + C NT GGY C C G+ DG CL
Sbjct: 880 VCPPASSKCINTEGGYVCRCSEGY--QGDGIHCL 911
Score = 33.9 bits (74), Expect = 1.5
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 4/39 (10%)
Query: 532 DPTLCENGHCSNTP----GGYECDCDVGFTRAADGRSCL 566
DP L +NG C + G C C GF +A+DG++CL
Sbjct: 743 DPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCL 781
>BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor
(beta-urogastrone) protein.
Length = 1207
Score = 109 bits (262), Expect = 3e-23
Identities = 70/211 (33%), Positives = 102/211 (48%), Gaps = 26/211 (12%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQC--RNTVGSYTCTC 354
C+H C G+ C+CREG+ +DG++C +D G + GG+ +N V T
Sbjct: 752 CEHICKKRLGTAWCSCREGFMKASDGKTCLALD----GHQLLAGGEVDLKNQV-----TP 802
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGS 413
D L + +I E ++ IM+S D+ D P C C +
Sbjct: 803 LDILSKTRVSE----DNITESQHMLVAEIMVS-DQ-----DDCAPVGCSMYARCISEGED 852
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD-CINLPGSFQCRCRDGWRGDGAT 472
CQC G++ G C+D DECE+G C PA+ CIN G + CRC +G++GDG
Sbjct: 853 ATCQCLKGFA---GDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIH 909
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C D+DEC C A+C NT+G + C+C
Sbjct: 910 CLDIDECQLGVHSCGENASCTNTEGGYTCMC 940
Score = 93.1 bits (221), Expect = 2e-18
Identities = 48/122 (39%), Positives = 62/122 (50%), Gaps = 13/122 (10%)
Query: 433 TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRAT- 491
+D D+C C + A CI+ C+C G+ GDG C D+DEC C P ++
Sbjct: 830 SDQDDCAPVGCSMY--ARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSK 887
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYEC 550
C NT+G + C C GY+GDG C+DIDEC C EN C+NT GGY C
Sbjct: 888 CINTEGGYVCRCSEGYQGDG---------IHCLDIDECQLGVHSCGENASCTNTEGGYTC 938
Query: 551 DC 552
C
Sbjct: 939 MC 940
Score = 77.8 bits (183), Expect = 1e-13
Identities = 49/163 (30%), Positives = 63/163 (38%), Gaps = 5/163 (3%)
Query: 164 CEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAG 223
C++ G C C S C C GY K C D++ECA + C G C NT G
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPG 376
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSH 283
S+ C C G L PD C + C CS+ G C C EG +
Sbjct: 377 SYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL-CFCPEGSVLE--RDG 433
Query: 284 XXXXXXXXXXXXRCQHSCVN-TPGSYHCTCREGWHLRADGRSC 325
C CV +P S+ C C G+ L+ D +SC
Sbjct: 434 KTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSC 476
Score = 77.0 bits (181), Expect = 2e-13
Identities = 45/128 (35%), Positives = 58/128 (45%), Gaps = 10/128 (7%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC--GDGDCH 177
++CA G + RC + TC C G+ D K C D++ECE+ VC C
Sbjct: 833 DDCAPV-GCSMYARCISEGEDATCQCLKGFAGDGK--LCSDIDECEMGVPVCPPASSKCI 889
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELA 236
NTEG + C C GY+ D C+DIDEC C C NT G + C C L+
Sbjct: 890 NTEGGYVCRCSEGYQGDGIH--CLDIDECQLGVHSCGENASCTNTEGGYTCMCAG--RLS 945
Query: 237 PDRLSCKD 244
L C D
Sbjct: 946 EPGLICPD 953
Score = 75.4 bits (177), Expect = 5e-13
Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 1/112 (0%)
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
C + G CS+ C + ++ C+C EGYA S + + C C NTPGS
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPGS 377
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
Y+CTC G+ L DG+ C + C C C T C C +G V
Sbjct: 378 YYCTCPVGFVLLPDGKRCHQLVSCPRNVSEC-SHDCVLTSEGPLCFCPEGSV 428
Score = 70.1 bits (164), Expect = 2e-11
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 11/149 (7%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
C C S C C G L+ DR C+D++EC+ + C+ G C+N G+Y C C
Sbjct: 325 CSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPGSYYCTCP 383
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECA 332
G+ C H CV T C C EG L DG++ C+
Sbjct: 384 VGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKT------CS 437
Query: 333 GGARPCGGGQCRNTVG----SYTCTCTDG 357
G + P GG + V S+ C C G
Sbjct: 438 GCSSPDNGGCSQLCVPLSPVSWECDCFPG 466
Score = 69.7 bits (163), Expect = 3e-11
Identities = 58/217 (26%), Positives = 81/217 (37%), Gaps = 19/217 (8%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C G C H C+ LG C C G+ K S TC+ ++ +++ G G+ D N
Sbjct: 745 CLYQNGGCEH-ICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAG--GEVDLKNQVT 801
Query: 182 SFTCHCRPGYKADDFSK---------ICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
+ D+ ++ + D D+CA RC++ C+C G
Sbjct: 802 PLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAP-VGCSMYARCISEGEDATCQCLKG 860
Query: 233 MELAPDRLSCKDIDECSITSGIC--SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
A D C DIDEC + +C ++ C N G Y C C EGY +
Sbjct: 861 --FAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQL 918
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRD 327
SC NT G Y C C L G C D
Sbjct: 919 GVHSCGENASCTNTEGGYTCMC--AGRLSEPGLICPD 953
Score = 66.9 bits (156), Expect = 2e-10
Identities = 47/154 (30%), Positives = 58/154 (37%), Gaps = 4/154 (2%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C G C C L C C GY C DVNEC + C G C NT G
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPG 376
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
S+ C C G+ K C + C N + C CV T+ C C G L D +
Sbjct: 377 SYYCTCPVGFVLLPDGKRCHQLVSCPRNVSEC-SHDCVLTSEGPLCFCPEGSVLERDGKT 435
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C S +G CS +++C C GY
Sbjct: 436 CSGCS--SPDNGGCSQLCVPLSPVSWECDCFPGY 467
Score = 63.3 bits (147), Expect = 2e-09
Identities = 47/166 (28%), Positives = 65/166 (39%), Gaps = 16/166 (9%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR 461
C + C + S +C C +GY++ ++ C D +EC C C N PGS+ C
Sbjct: 325 CSSTVCGQDLQSHLCMCAEGYALSRDR-KYCEDVNECAFWNHGC--TLGCKNTPGSYYCT 381
Query: 462 CRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C G+ DG C + C N C C T C C G + G C
Sbjct: 382 CPVGFVLLPDGKRCHQLVSCPRNVSECSH--DCVLTSEGPLCFCPEGSVLERDG--KTCS 437
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
S D C+ LC +P +ECDC G+ D +SC
Sbjct: 438 GCSSPDNGGCSQ---LC----VPLSPVSWECDCFPGYDLQLDEKSC 476
Score = 56.0 bits (129), Expect = 3e-07
Identities = 42/132 (31%), Positives = 55/132 (41%), Gaps = 13/132 (9%)
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANT 495
C+L +C C S C C +G+ D CEDV+EC N GC C NT
Sbjct: 318 CKLRKGNCSSTV-CGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGC--TLGCKNT 374
Query: 496 DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
GS+ C C G+ G R V ++ EC++D C T G C C G
Sbjct: 375 PGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHD--------CVLTSEGPLCFCPEG 426
Query: 556 FTRAADGRSCLG 567
DG++C G
Sbjct: 427 SVLERDGKTCSG 438
Score = 50.0 bits (114), Expect = 2e-05
Identities = 33/94 (35%), Positives = 39/94 (41%), Gaps = 15/94 (15%)
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D D+C GC A C + C C G+ GDG C DIDEC
Sbjct: 831 DQDDCAPV--GCSMYARCISEGEDATCQCLKGFAGDGK---------LCSDIDECEMGVP 879
Query: 535 LCE--NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C + C NT GGY C C G+ DG CL
Sbjct: 880 VCPPASSKCINTEGGYVCRCSEGY--QGDGIHCL 911
Score = 33.9 bits (74), Expect = 1.5
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 4/39 (10%)
Query: 532 DPTLCENGHCSNTP----GGYECDCDVGFTRAADGRSCL 566
DP L +NG C + G C C GF +A+DG++CL
Sbjct: 743 DPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCL 781
>BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multiple
6 protein.
Length = 553
Score = 109 bits (262), Expect = 3e-23
Identities = 62/163 (38%), Positives = 85/163 (52%), Gaps = 10/163 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC P C H RC N G + C C G+ + TCV+ C +++ C C
Sbjct: 94 DVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHML-MPDATCVNSRTCAMIN--C-QYSCE 148
Query: 178 NTEGSFTCHC-RPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMEL 235
+TE C C G + + C+DIDECA +C RCVNT GS+ C+C G EL
Sbjct: 149 DTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFEL 208
Query: 236 A--PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
R C DI+EC++ S CS+ A C N G+++C C +GY
Sbjct: 209 QYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 100 bits (239), Expect = 2e-20
Identities = 73/219 (33%), Positives = 95/219 (43%), Gaps = 22/219 (10%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV-DVNECEIVDGVCGDGDCH 177
V E PG C G C +G C CFPGY TC DVNEC + C C
Sbjct: 60 VCEATCEPG-CKFGEC---VGPNKCRCFPGYT----GKTCSQDVNECGMKPRPC-QHRCV 110
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHGMELA 236
NT GS+ C C G+ CV+ CA + C+ C +T +C C G+ LA
Sbjct: 111 NTHGSYKCFCLSGHMLMP-DATCVNSRTCAMIN--CQYS-CEDTEEGPQCLCPSSGLRLA 166
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX--XXX 293
P+ C DIDEC+ IC N C N G+Y C C G+ +
Sbjct: 167 PNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMD 226
Query: 294 XXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDE 330
C H +C NT GS+ C C++G+ + +G C I E
Sbjct: 227 SHTCSHHANCFNTQGSFKCKCKQGY--KGNGLRCSAIPE 263
Score = 97.5 bits (232), Expect = 1e-19
Identities = 78/254 (30%), Positives = 108/254 (42%), Gaps = 35/254 (13%)
Query: 229 CGHGMELAPD---RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXX 285
C +G +LA R + K + E + G C G C +G +C C GY T K+
Sbjct: 41 CHYGTKLACCYGWRRNSKGVCEATCEPG-CKFGEC---VGPNKCRCFPGY---TGKTCSQ 93
Query: 286 XXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN 345
CQH CVNT GSY C C G L D +C + CA C C +
Sbjct: 94 DVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCA--MINCQYS-CED 149
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
T C C + A + C DIDECA K + P
Sbjct: 150 TEEGPQCLCPSSGLRLAPNGRD-CLDIDECAS-------------GKVICPYNRR----- 190
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPA-CTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
C NT GS+ C+C G+ ++ G C D +EC + + C A+C N GSF+C+C+
Sbjct: 191 -CVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQ 249
Query: 465 GWRGDGATCEDVDE 478
G++G+G C + E
Sbjct: 250 GYKGNGLRCSAIPE 263
Score = 95.5 bits (227), Expect = 4e-19
Identities = 71/214 (33%), Positives = 94/214 (43%), Gaps = 42/214 (19%)
Query: 306 GSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSA 362
G C C G+ G++C +D++EC RPC +C NT GSY C C G L+P A
Sbjct: 76 GPNKCRCFPGY----TGKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA 130
Query: 363 AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD-G 421
TC + CA ++ Q SC +T C CP G
Sbjct: 131 -----TCVNSRTCA----------------MINCQY-------SCEDTEEGPQCLCPSSG 162
Query: 422 YSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR----GDGATCEDVD 477
+ P G C D DEC G C C+N GS+ C+C G+ C D++
Sbjct: 163 LRLAPN-GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG 511
EC ++ C A C NT GSF+C C GYKG+G
Sbjct: 222 ECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNG 255
Score = 91.5 bits (217), Expect = 7e-18
Identities = 71/219 (32%), Positives = 98/219 (44%), Gaps = 23/219 (10%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
C G+ ++SK V E G C G+C G C C PGY S+ D++
Sbjct: 49 CCYGWRRNSKG-----VCEATCEPG-CKFGEC---VGPNKCRCFPGYTGKTCSQ---DVN 96
Query: 205 ECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQM 264
EC C+ RCVNT GS++C C G L PD +C + C++ + C +CE+
Sbjct: 97 ECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCAMIN--CQY-SCEDTE 151
Query: 265 GTYQCVC-DEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREGWHLR-A 320
QC+C G + C ++ CVNT GSY+C C G+ L+
Sbjct: 152 EGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYI 211
Query: 321 DGR-SCRDIDECAGGARPCGG-GQCRNTVGSYTCTCTDG 357
GR C DI+EC + C C NT GS+ C C G
Sbjct: 212 SGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG 250
Score = 90.2 bits (214), Expect = 2e-17
Identities = 65/212 (30%), Positives = 87/212 (41%), Gaps = 31/212 (14%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
C+ G CV G +C C G + +D++EC + C + C N G+Y+C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT---GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCL 121
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDEC 331
G+ + CQ+SC +T C C G L +GR C DIDEC
Sbjct: 122 SGHM---LMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDEC 178
Query: 332 AGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
A G C +C NT GSY C C G + C DI+EC ++D
Sbjct: 179 ASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC----------TMDSH 228
Query: 391 QKSVDPQIPELCGAGSCHNTIGSFVCQCPDGY 422
S +C NT GSF C+C GY
Sbjct: 229 TCS---------HHANCFNTQGSFKCKCKQGY 251
Score = 86.6 bits (205), Expect = 2e-16
Identities = 49/154 (31%), Positives = 71/154 (46%), Gaps = 15/154 (9%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDG 465
C NT GS+ C C G+ + P+ C + C + C C + QC C G
Sbjct: 109 CVNTHGSYKCFCLSGHMLMPDA--TCVNSRTCAMINCQY----SCEDTEEGPQCLCPSSG 162
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
R +G C D+DEC + C C NT GS+ C C G++ L+ + Y C
Sbjct: 163 LRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFE-----LQYISGRYDC 217
Query: 524 VDIDECANDPTLC-ENGHCSNTPGGYECDCDVGF 556
+DI+EC D C + +C NT G ++C C G+
Sbjct: 218 IDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 76.2 bits (179), Expect = 3e-13
Identities = 53/158 (33%), Positives = 73/158 (46%), Gaps = 23/158 (14%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQC 460
C G C +G C+C GY+ G C+ D +EC + C C+N GS++C
Sbjct: 69 CKFGEC---VGPNKCRCFPGYT-----GKTCSQDVNECGMKPRPCQHR--CVNTHGSYKC 118
Query: 461 RCRDGWR-GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C G ATC + C N C + +C +T+ +CLC + GLR
Sbjct: 119 FCLSGHMLMPDATCVNSRTCAMIN--C--QYSCEDTEEGPQCLCPSS------GLRLAPN 168
Query: 520 VYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGF 556
C+DIDECA+ +C N C NT G Y C C +GF
Sbjct: 169 GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF 206
Score = 70.5 bits (165), Expect = 1e-11
Identities = 30/82 (36%), Positives = 47/82 (57%), Gaps = 4/82 (4%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD--SKNHTCVDVNECEIVDGVCGD 173
++++ECA+ +C + R C N G + C C G+E S + C+D+NEC + C
Sbjct: 173 LDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSH 232
Query: 174 -GDCHNTEGSFTCHCRPGYKAD 194
+C NT+GSF C C+ GYK +
Sbjct: 233 HANCFNTQGSFKCKCKQGYKGN 254
Score = 33.5 bits (73), Expect = 2.0
Identities = 15/52 (28%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 117 MEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIV 167
+++NEC C H C N G F C C GY+ + + + N + V
Sbjct: 218 IDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEV 269
>AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal growth
factor (beta-urogastrone) protein.
Length = 1152
Score = 109 bits (262), Expect = 3e-23
Identities = 70/211 (33%), Positives = 102/211 (48%), Gaps = 26/211 (12%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQC--RNTVGSYTCTC 354
C+H C G+ C+CREG+ +DG++C +D G + GG+ +N V T
Sbjct: 752 CEHICKKRLGTAWCSCREGFMKASDGKTCLALD----GHQLLAGGEVDLKNQV-----TP 802
Query: 355 TDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGA-GSCHNTIGS 413
D L + +I E ++ IM+S D+ D P C C +
Sbjct: 803 LDILSKTRVSE----DNITESQHMLVAEIMVS-DQ-----DDCAPVGCSMYARCISEGED 852
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAAD-CINLPGSFQCRCRDGWRGDGAT 472
CQC G++ G C+D DECE+G C PA+ CIN G + CRC +G++GDG
Sbjct: 853 ATCQCLKGFA---GDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIH 909
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLC 503
C D+DEC C A+C NT+G + C+C
Sbjct: 910 CLDIDECQLGVHSCGENASCTNTEGGYTCMC 940
Score = 93.1 bits (221), Expect = 2e-18
Identities = 48/122 (39%), Positives = 62/122 (50%), Gaps = 13/122 (10%)
Query: 433 TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRAT- 491
+D D+C C + A CI+ C+C G+ GDG C D+DEC C P ++
Sbjct: 830 SDQDDCAPVGCSMY--ARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSK 887
Query: 492 CANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC-ENGHCSNTPGGYEC 550
C NT+G + C C GY+GDG C+DIDEC C EN C+NT GGY C
Sbjct: 888 CINTEGGYVCRCSEGYQGDG---------IHCLDIDECQLGVHSCGENASCTNTEGGYTC 938
Query: 551 DC 552
C
Sbjct: 939 MC 940
Score = 77.8 bits (183), Expect = 1e-13
Identities = 49/163 (30%), Positives = 63/163 (38%), Gaps = 5/163 (3%)
Query: 164 CEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAG 223
C++ G C C S C C GY K C D++ECA + C G C NT G
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPG 376
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSH 283
S+ C C G L PD C + C CS+ G C C EG +
Sbjct: 377 SYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL-CFCPEGSVLE--RDG 433
Query: 284 XXXXXXXXXXXXRCQHSCVN-TPGSYHCTCREGWHLRADGRSC 325
C CV +P S+ C C G+ L+ D +SC
Sbjct: 434 KTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSC 476
Score = 77.0 bits (181), Expect = 2e-13
Identities = 45/128 (35%), Positives = 58/128 (45%), Gaps = 10/128 (7%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC--GDGDCH 177
++CA G + RC + TC C G+ D K C D++ECE+ VC C
Sbjct: 833 DDCAPV-GCSMYARCISEGEDATCQCLKGFAGDGK--LCSDIDECEMGVPVCPPASSKCI 889
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELA 236
NTEG + C C GY+ D C+DIDEC C C NT G + C C L+
Sbjct: 890 NTEGGYVCRCSEGYQGDGIH--CLDIDECQLGVHSCGENASCTNTEGGYTCMCAG--RLS 945
Query: 237 PDRLSCKD 244
L C D
Sbjct: 946 EPGLICPD 953
Score = 75.4 bits (177), Expect = 5e-13
Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 1/112 (0%)
Query: 248 CSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGS 307
C + G CS+ C + ++ C+C EGYA S + + C C NTPGS
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPGS 377
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
Y+CTC G+ L DG+ C + C C C T C C +G V
Sbjct: 378 YYCTCPVGFVLLPDGKRCHQLVSCPRNVSEC-SHDCVLTSEGPLCFCPEGSV 428
Score = 70.1 bits (164), Expect = 2e-11
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 11/149 (7%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
C C S C C G L+ DR C+D++EC+ + C+ G C+N G+Y C C
Sbjct: 325 CSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPGSYYCTCP 383
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECA 332
G+ C H CV T C C EG L DG++ C+
Sbjct: 384 VGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKT------CS 437
Query: 333 GGARPCGGGQCRNTVG----SYTCTCTDG 357
G + P GG + V S+ C C G
Sbjct: 438 GCSSPDNGGCSQLCVPLSPVSWECDCFPG 466
Score = 69.7 bits (163), Expect = 3e-11
Identities = 58/217 (26%), Positives = 81/217 (37%), Gaps = 19/217 (8%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C G C H C+ LG C C G+ K S TC+ ++ +++ G G+ D N
Sbjct: 745 CLYQNGGCEH-ICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAG--GEVDLKNQVT 801
Query: 182 SFTCHCRPGYKADDFSK---------ICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
+ D+ ++ + D D+CA RC++ C+C G
Sbjct: 802 PLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAP-VGCSMYARCISEGEDATCQCLKG 860
Query: 233 MELAPDRLSCKDIDECSITSGIC--SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX 290
A D C DIDEC + +C ++ C N G Y C C EGY +
Sbjct: 861 --FAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQL 918
Query: 291 XXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRD 327
SC NT G Y C C L G C D
Sbjct: 919 GVHSCGENASCTNTEGGYTCMC--AGRLSEPGLICPD 953
Score = 66.9 bits (156), Expect = 2e-10
Identities = 47/154 (30%), Positives = 58/154 (37%), Gaps = 4/154 (2%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEG 181
C G C C L C C GY C DVNEC + C G C NT G
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG-CKNTPG 376
Query: 182 SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLS 241
S+ C C G+ K C + C N + C CV T+ C C G L D +
Sbjct: 377 SYYCTCPVGFVLLPDGKRCHQLVSCPRNVSEC-SHDCVLTSEGPLCFCPEGSVLERDGKT 435
Query: 242 CKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C S +G CS +++C C GY
Sbjct: 436 CSGCS--SPDNGGCSQLCVPLSPVSWECDCFPGY 467
Score = 63.3 bits (147), Expect = 2e-09
Identities = 47/166 (28%), Positives = 65/166 (39%), Gaps = 16/166 (9%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCR 461
C + C + S +C C +GY++ ++ C D +EC C C N PGS+ C
Sbjct: 325 CSSTVCGQDLQSHLCMCAEGYALSRDR-KYCEDVNECAFWNHGC--TLGCKNTPGSYYCT 381
Query: 462 CRDGW--RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C G+ DG C + C N C C T C C G + G C
Sbjct: 382 CPVGFVLLPDGKRCHQLVSCPRNVSECSH--DCVLTSEGPLCFCPEGSVLERDG--KTCS 437
Query: 520 VYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
S D C+ LC +P +ECDC G+ D +SC
Sbjct: 438 GCSSPDNGGCSQ---LC----VPLSPVSWECDCFPGYDLQLDEKSC 476
Score = 56.0 bits (129), Expect = 3e-07
Identities = 42/132 (31%), Positives = 55/132 (41%), Gaps = 13/132 (9%)
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCANT 495
C+L +C C S C C +G+ D CEDV+EC N GC C NT
Sbjct: 318 CKLRKGNCSSTV-CGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGC--TLGCKNT 374
Query: 496 DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
GS+ C C G+ G R V ++ EC++D C T G C C G
Sbjct: 375 PGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHD--------CVLTSEGPLCFCPEG 426
Query: 556 FTRAADGRSCLG 567
DG++C G
Sbjct: 427 SVLERDGKTCSG 438
Score = 50.0 bits (114), Expect = 2e-05
Identities = 33/94 (35%), Positives = 39/94 (41%), Gaps = 15/94 (15%)
Query: 475 DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
D D+C GC A C + C C G+ GDG C DIDEC
Sbjct: 831 DQDDCAPV--GCSMYARCISEGEDATCQCLKGFAGDGK---------LCSDIDECEMGVP 879
Query: 535 LCE--NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
+C + C NT GGY C C G+ DG CL
Sbjct: 880 VCPPASSKCINTEGGYVCRCSEGY--QGDGIHCL 911
Score = 33.9 bits (74), Expect = 1.5
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 4/39 (10%)
Query: 532 DPTLCENGHCSNTP----GGYECDCDVGFTRAADGRSCL 566
DP L +NG C + G C C GF +A+DG++CL
Sbjct: 743 DPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCL 781
>AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein.
Length = 338
Score = 109 bits (262), Expect = 3e-23
Identities = 62/163 (38%), Positives = 85/163 (52%), Gaps = 10/163 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC P C H RC N G + C C G+ + TCV+ C +++ C C
Sbjct: 94 DVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHML-MPDATCVNSRTCAMIN--C-QYSCE 148
Query: 178 NTEGSFTCHC-RPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMEL 235
+TE C C G + + C+DIDECA +C RCVNT GS+ C+C G EL
Sbjct: 149 DTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFEL 208
Query: 236 A--PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
R C DI+EC++ S CS+ A C N G+++C C +GY
Sbjct: 209 QYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 100 bits (239), Expect = 2e-20
Identities = 73/219 (33%), Positives = 95/219 (43%), Gaps = 22/219 (10%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV-DVNECEIVDGVCGDGDCH 177
V E PG C G C +G C CFPGY TC DVNEC + C C
Sbjct: 60 VCEATCEPG-CKFGEC---VGPNKCRCFPGYT----GKTCSQDVNECGMKPRPC-QHRCV 110
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHGMELA 236
NT GS+ C C G+ CV+ CA + C+ C +T +C C G+ LA
Sbjct: 111 NTHGSYKCFCLSGHMLMP-DATCVNSRTCAMIN--CQYS-CEDTEEGPQCLCPSSGLRLA 166
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX--XXX 293
P+ C DIDEC+ IC N C N G+Y C C G+ +
Sbjct: 167 PNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMD 226
Query: 294 XXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDE 330
C H +C NT GS+ C C++G+ + +G C I E
Sbjct: 227 SHTCSHHANCFNTQGSFKCKCKQGY--KGNGLRCSAIPE 263
Score = 97.5 bits (232), Expect = 1e-19
Identities = 78/254 (30%), Positives = 108/254 (42%), Gaps = 35/254 (13%)
Query: 229 CGHGMELAPD---RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXX 285
C +G +LA R + K + E + G C G C +G +C C GY T K+
Sbjct: 41 CHYGTKLACCYGWRRNSKGVCEATCEPG-CKFGEC---VGPNKCRCFPGY---TGKTCSQ 93
Query: 286 XXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN 345
CQH CVNT GSY C C G L D +C + CA C C +
Sbjct: 94 DVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCA--MINCQYS-CED 149
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
T C C + A + C DIDECA K + P
Sbjct: 150 TEEGPQCLCPSSGLRLAPNGRD-CLDIDECAS-------------GKVICPYNRR----- 190
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPA-CTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
C NT GS+ C+C G+ ++ G C D +EC + + C A+C N GSF+C+C+
Sbjct: 191 -CVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQ 249
Query: 465 GWRGDGATCEDVDE 478
G++G+G C + E
Sbjct: 250 GYKGNGLRCSAIPE 263
Score = 95.5 bits (227), Expect = 4e-19
Identities = 71/214 (33%), Positives = 94/214 (43%), Gaps = 42/214 (19%)
Query: 306 GSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSA 362
G C C G+ G++C +D++EC RPC +C NT GSY C C G L+P A
Sbjct: 76 GPNKCRCFPGY----TGKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA 130
Query: 363 AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD-G 421
TC + CA ++ Q SC +T C CP G
Sbjct: 131 -----TCVNSRTCA----------------MINCQY-------SCEDTEEGPQCLCPSSG 162
Query: 422 YSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR----GDGATCEDVD 477
+ P G C D DEC G C C+N GS+ C+C G+ C D++
Sbjct: 163 LRLAPN-GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG 511
EC ++ C A C NT GSF+C C GYKG+G
Sbjct: 222 ECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNG 255
Score = 91.5 bits (217), Expect = 7e-18
Identities = 71/219 (32%), Positives = 98/219 (44%), Gaps = 23/219 (10%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
C G+ ++SK V E G C G+C G C C PGY S+ D++
Sbjct: 49 CCYGWRRNSKG-----VCEATCEPG-CKFGEC---VGPNKCRCFPGYTGKTCSQ---DVN 96
Query: 205 ECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQM 264
EC C+ RCVNT GS++C C G L PD +C + C++ + C +CE+
Sbjct: 97 ECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCAMIN--CQY-SCEDTE 151
Query: 265 GTYQCVC-DEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREGWHLR-A 320
QC+C G + C ++ CVNT GSY+C C G+ L+
Sbjct: 152 EGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYI 211
Query: 321 DGR-SCRDIDECAGGARPCGG-GQCRNTVGSYTCTCTDG 357
GR C DI+EC + C C NT GS+ C C G
Sbjct: 212 SGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG 250
Score = 90.2 bits (214), Expect = 2e-17
Identities = 65/212 (30%), Positives = 87/212 (41%), Gaps = 31/212 (14%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
C+ G CV G +C C G + +D++EC + C + C N G+Y+C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT---GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCL 121
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDEC 331
G+ + CQ+SC +T C C G L +GR C DIDEC
Sbjct: 122 SGHM---LMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDEC 178
Query: 332 AGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
A G C +C NT GSY C C G + C DI+EC ++D
Sbjct: 179 ASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC----------TMDSH 228
Query: 391 QKSVDPQIPELCGAGSCHNTIGSFVCQCPDGY 422
S +C NT GSF C+C GY
Sbjct: 229 TCS---------HHANCFNTQGSFKCKCKQGY 251
Score = 86.6 bits (205), Expect = 2e-16
Identities = 49/154 (31%), Positives = 71/154 (46%), Gaps = 15/154 (9%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDG 465
C NT GS+ C C G+ + P+ C + C + C C + QC C G
Sbjct: 109 CVNTHGSYKCFCLSGHMLMPDA--TCVNSRTCAMINCQY----SCEDTEEGPQCLCPSSG 162
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
R +G C D+DEC + C C NT GS+ C C G++ L+ + Y C
Sbjct: 163 LRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFE-----LQYISGRYDC 217
Query: 524 VDIDECANDPTLC-ENGHCSNTPGGYECDCDVGF 556
+DI+EC D C + +C NT G ++C C G+
Sbjct: 218 IDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 76.2 bits (179), Expect = 3e-13
Identities = 53/158 (33%), Positives = 73/158 (46%), Gaps = 23/158 (14%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQC 460
C G C +G C+C GY+ G C+ D +EC + C C+N GS++C
Sbjct: 69 CKFGEC---VGPNKCRCFPGYT-----GKTCSQDVNECGMKPRPCQHR--CVNTHGSYKC 118
Query: 461 RCRDGWR-GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C G ATC + C N C + +C +T+ +CLC + GLR
Sbjct: 119 FCLSGHMLMPDATCVNSRTCAMIN--C--QYSCEDTEEGPQCLCPSS------GLRLAPN 168
Query: 520 VYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGF 556
C+DIDECA+ +C N C NT G Y C C +GF
Sbjct: 169 GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF 206
Score = 70.5 bits (165), Expect = 1e-11
Identities = 30/82 (36%), Positives = 47/82 (57%), Gaps = 4/82 (4%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD--SKNHTCVDVNECEIVDGVCGD 173
++++ECA+ +C + R C N G + C C G+E S + C+D+NEC + C
Sbjct: 173 LDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSH 232
Query: 174 -GDCHNTEGSFTCHCRPGYKAD 194
+C NT+GSF C C+ GYK +
Sbjct: 233 HANCFNTQGSFKCKCKQGYKGN 254
Score = 33.5 bits (73), Expect = 2.0
Identities = 15/52 (28%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 117 MEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIV 167
+++NEC C H C N G F C C GY+ + + + N + V
Sbjct: 218 IDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEV 269
>AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ90733 fis, clone PLACE1010251, highly similar to
Epidermal growth factor-like protein 6 precursor. ).
Length = 553
Score = 109 bits (262), Expect = 3e-23
Identities = 62/163 (38%), Positives = 85/163 (52%), Gaps = 10/163 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC P C H RC N G + C C G+ + TCV+ C +++ C C
Sbjct: 94 DVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHML-MPDATCVNSRTCAMIN--C-QYSCE 148
Query: 178 NTEGSFTCHC-RPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMEL 235
+TE C C G + + C+DIDECA +C RCVNT GS+ C+C G EL
Sbjct: 149 DTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFEL 208
Query: 236 A--PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
R C DI+EC++ S CS+ A C N G+++C C +GY
Sbjct: 209 QYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 100 bits (239), Expect = 2e-20
Identities = 73/219 (33%), Positives = 95/219 (43%), Gaps = 22/219 (10%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV-DVNECEIVDGVCGDGDCH 177
V E PG C G C +G C CFPGY TC DVNEC + C C
Sbjct: 60 VCEATCEPG-CKFGEC---VGPNKCRCFPGYT----GKTCSQDVNECGMKPRPC-QHRCV 110
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHGMELA 236
NT GS+ C C G+ CV+ CA + C+ C +T +C C G+ LA
Sbjct: 111 NTHGSYKCFCLSGHMLMP-DATCVNSRTCAMIN--CQYS-CEDTEEGPQCLCPSSGLRLA 166
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX--XXX 293
P+ C DIDEC+ IC N C N G+Y C C G+ +
Sbjct: 167 PNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMD 226
Query: 294 XXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDE 330
C H +C NT GS+ C C++G+ + +G C I E
Sbjct: 227 SHTCSHHANCFNTQGSFKCKCKQGY--KGNGLRCSAIPE 263
Score = 97.5 bits (232), Expect = 1e-19
Identities = 78/254 (30%), Positives = 108/254 (42%), Gaps = 35/254 (13%)
Query: 229 CGHGMELAPD---RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXX 285
C +G +LA R + K + E + G C G C +G +C C GY T K+
Sbjct: 41 CHYGTKLACCYGWRRNSKGVCEATCEPG-CKFGEC---VGPNKCRCFPGY---TGKTCSQ 93
Query: 286 XXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN 345
CQH CVNT GSY C C G L D +C + CA C C +
Sbjct: 94 DVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCA--MINCQYS-CED 149
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
T C C + A + C DIDECA K + P
Sbjct: 150 TEEGPQCLCPSSGLRLAPNGRD-CLDIDECAS-------------GKVICPYNRR----- 190
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPA-CTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
C NT GS+ C+C G+ ++ G C D +EC + + C A+C N GSF+C+C+
Sbjct: 191 -CVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQ 249
Query: 465 GWRGDGATCEDVDE 478
G++G+G C + E
Sbjct: 250 GYKGNGLRCSAIPE 263
Score = 95.5 bits (227), Expect = 4e-19
Identities = 71/214 (33%), Positives = 94/214 (43%), Gaps = 42/214 (19%)
Query: 306 GSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSA 362
G C C G+ G++C +D++EC RPC +C NT GSY C C G L+P A
Sbjct: 76 GPNKCRCFPGY----TGKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA 130
Query: 363 AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD-G 421
TC + CA ++ Q SC +T C CP G
Sbjct: 131 -----TCVNSRTCA----------------MINCQY-------SCEDTEEGPQCLCPSSG 162
Query: 422 YSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR----GDGATCEDVD 477
+ P G C D DEC G C C+N GS+ C+C G+ C D++
Sbjct: 163 LRLAPN-GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG 511
EC ++ C A C NT GSF+C C GYKG+G
Sbjct: 222 ECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNG 255
Score = 91.5 bits (217), Expect = 7e-18
Identities = 71/219 (32%), Positives = 98/219 (44%), Gaps = 23/219 (10%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
C G+ ++SK V E G C G+C G C C PGY S+ D++
Sbjct: 49 CCYGWRRNSKG-----VCEATCEPG-CKFGEC---VGPNKCRCFPGYTGKTCSQ---DVN 96
Query: 205 ECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQM 264
EC C+ RCVNT GS++C C G L PD +C + C++ + C +CE+
Sbjct: 97 ECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCAMIN--CQY-SCEDTE 151
Query: 265 GTYQCVC-DEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREGWHLR-A 320
QC+C G + C ++ CVNT GSY+C C G+ L+
Sbjct: 152 EGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYI 211
Query: 321 DGR-SCRDIDECAGGARPCGG-GQCRNTVGSYTCTCTDG 357
GR C DI+EC + C C NT GS+ C C G
Sbjct: 212 SGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG 250
Score = 90.2 bits (214), Expect = 2e-17
Identities = 65/212 (30%), Positives = 87/212 (41%), Gaps = 31/212 (14%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
C+ G CV G +C C G + +D++EC + C + C N G+Y+C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT---GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCL 121
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDEC 331
G+ + CQ+SC +T C C G L +GR C DIDEC
Sbjct: 122 SGHM---LMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDEC 178
Query: 332 AGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
A G C +C NT GSY C C G + C DI+EC ++D
Sbjct: 179 ASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC----------TMDSH 228
Query: 391 QKSVDPQIPELCGAGSCHNTIGSFVCQCPDGY 422
S +C NT GSF C+C GY
Sbjct: 229 TCS---------HHANCFNTQGSFKCKCKQGY 251
Score = 86.6 bits (205), Expect = 2e-16
Identities = 49/154 (31%), Positives = 71/154 (46%), Gaps = 15/154 (9%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDG 465
C NT GS+ C C G+ + P+ C + C + C C + QC C G
Sbjct: 109 CVNTHGSYKCFCLSGHMLMPDA--TCVNSRTCAMINCQY----SCEDTEEGPQCLCPSSG 162
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
R +G C D+DEC + C C NT GS+ C C G++ L+ + Y C
Sbjct: 163 LRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFE-----LQYISGRYDC 217
Query: 524 VDIDECANDPTLC-ENGHCSNTPGGYECDCDVGF 556
+DI+EC D C + +C NT G ++C C G+
Sbjct: 218 IDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 76.2 bits (179), Expect = 3e-13
Identities = 53/158 (33%), Positives = 73/158 (46%), Gaps = 23/158 (14%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQC 460
C G C +G C+C GY+ G C+ D +EC + C C+N GS++C
Sbjct: 69 CKFGEC---VGPNKCRCFPGYT-----GKTCSQDVNECGMKPRPCQHR--CVNTHGSYKC 118
Query: 461 RCRDGWR-GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C G ATC + C N C + +C +T+ +CLC + GLR
Sbjct: 119 FCLSGHMLMPDATCVNSRTCAMIN--C--QYSCEDTEEGPQCLCPSS------GLRLAPN 168
Query: 520 VYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGF 556
C+DIDECA+ +C N C NT G Y C C +GF
Sbjct: 169 GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF 206
Score = 70.5 bits (165), Expect = 1e-11
Identities = 30/82 (36%), Positives = 47/82 (57%), Gaps = 4/82 (4%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD--SKNHTCVDVNECEIVDGVCGD 173
++++ECA+ +C + R C N G + C C G+E S + C+D+NEC + C
Sbjct: 173 LDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSH 232
Query: 174 -GDCHNTEGSFTCHCRPGYKAD 194
+C NT+GSF C C+ GYK +
Sbjct: 233 HANCFNTQGSFKCKCKQGYKGN 254
Score = 33.5 bits (73), Expect = 2.0
Identities = 15/52 (28%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 117 MEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIV 167
+++NEC C H C N G F C C GY+ + + + N + V
Sbjct: 218 IDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEV 269
>AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein
protein.
Length = 554
Score = 109 bits (262), Expect = 3e-23
Identities = 62/163 (38%), Positives = 85/163 (52%), Gaps = 10/163 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC P C H RC N G + C C G+ + TCV+ C +++ C C
Sbjct: 94 DVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHML-MPDATCVNSRTCAMIN--C-QYSCE 148
Query: 178 NTEGSFTCHC-RPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMEL 235
+TE C C G + + C+DIDECA +C RCVNT GS+ C+C G EL
Sbjct: 149 DTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFEL 208
Query: 236 A--PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
R C DI+EC++ S CS+ A C N G+++C C +GY
Sbjct: 209 QYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 100 bits (239), Expect = 2e-20
Identities = 73/219 (33%), Positives = 95/219 (43%), Gaps = 22/219 (10%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV-DVNECEIVDGVCGDGDCH 177
V E PG C G C +G C CFPGY TC DVNEC + C C
Sbjct: 60 VCEATCEPG-CKFGEC---VGPNKCRCFPGYT----GKTCSQDVNECGMKPRPC-QHRCV 110
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHGMELA 236
NT GS+ C C G+ CV+ CA + C+ C +T +C C G+ LA
Sbjct: 111 NTHGSYKCFCLSGHMLMP-DATCVNSRTCAMIN--CQYS-CEDTEEGPQCLCPSSGLRLA 166
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX--XXX 293
P+ C DIDEC+ IC N C N G+Y C C G+ +
Sbjct: 167 PNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMD 226
Query: 294 XXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDE 330
C H +C NT GS+ C C++G+ + +G C I E
Sbjct: 227 SHTCSHHANCFNTQGSFKCKCKQGY--KGNGLRCSAIPE 263
Score = 97.5 bits (232), Expect = 1e-19
Identities = 78/254 (30%), Positives = 108/254 (42%), Gaps = 35/254 (13%)
Query: 229 CGHGMELAPD---RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXX 285
C +G +LA R + K + E + G C G C +G +C C GY T K+
Sbjct: 41 CHYGTKLACCYGWRRNSKGVCEATCEPG-CKFGEC---VGPNKCRCFPGY---TGKTCSQ 93
Query: 286 XXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN 345
CQH CVNT GSY C C G L D +C + CA C C +
Sbjct: 94 DVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCA--MINCQYS-CED 149
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
T C C + A + C DIDECA K + P
Sbjct: 150 TEEGPQCLCPSSGLRLAPNGRD-CLDIDECAS-------------GKVICPYNRR----- 190
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPA-CTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
C NT GS+ C+C G+ ++ G C D +EC + + C A+C N GSF+C+C+
Sbjct: 191 -CVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQ 249
Query: 465 GWRGDGATCEDVDE 478
G++G+G C + E
Sbjct: 250 GYKGNGLRCSAIPE 263
Score = 95.5 bits (227), Expect = 4e-19
Identities = 71/214 (33%), Positives = 94/214 (43%), Gaps = 42/214 (19%)
Query: 306 GSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSA 362
G C C G+ G++C +D++EC RPC +C NT GSY C C G L+P A
Sbjct: 76 GPNKCRCFPGY----TGKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA 130
Query: 363 AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD-G 421
TC + CA ++ Q SC +T C CP G
Sbjct: 131 -----TCVNSRTCA----------------MINCQY-------SCEDTEEGPQCLCPSSG 162
Query: 422 YSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR----GDGATCEDVD 477
+ P G C D DEC G C C+N GS+ C+C G+ C D++
Sbjct: 163 LRLAPN-GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG 511
EC ++ C A C NT GSF+C C GYKG+G
Sbjct: 222 ECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNG 255
Score = 91.5 bits (217), Expect = 7e-18
Identities = 71/219 (32%), Positives = 98/219 (44%), Gaps = 23/219 (10%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
C G+ ++SK V E G C G+C G C C PGY S+ D++
Sbjct: 49 CCYGWRRNSKG-----VCEATCEPG-CKFGEC---VGPNKCRCFPGYTGKTCSQ---DVN 96
Query: 205 ECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQM 264
EC C+ RCVNT GS++C C G L PD +C + C++ + C +CE+
Sbjct: 97 ECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCAMIN--CQY-SCEDTE 151
Query: 265 GTYQCVC-DEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREGWHLR-A 320
QC+C G + C ++ CVNT GSY+C C G+ L+
Sbjct: 152 EGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYI 211
Query: 321 DGR-SCRDIDECAGGARPCGG-GQCRNTVGSYTCTCTDG 357
GR C DI+EC + C C NT GS+ C C G
Sbjct: 212 SGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG 250
Score = 90.2 bits (214), Expect = 2e-17
Identities = 65/212 (30%), Positives = 87/212 (41%), Gaps = 31/212 (14%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
C+ G CV G +C C G + +D++EC + C + C N G+Y+C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT---GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCL 121
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDEC 331
G+ + CQ+SC +T C C G L +GR C DIDEC
Sbjct: 122 SGHM---LMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDEC 178
Query: 332 AGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
A G C +C NT GSY C C G + C DI+EC ++D
Sbjct: 179 ASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC----------TMDSH 228
Query: 391 QKSVDPQIPELCGAGSCHNTIGSFVCQCPDGY 422
S +C NT GSF C+C GY
Sbjct: 229 TCS---------HHANCFNTQGSFKCKCKQGY 251
Score = 86.6 bits (205), Expect = 2e-16
Identities = 49/154 (31%), Positives = 71/154 (46%), Gaps = 15/154 (9%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDG 465
C NT GS+ C C G+ + P+ C + C + C C + QC C G
Sbjct: 109 CVNTHGSYKCFCLSGHMLMPDA--TCVNSRTCAMINCQY----SCEDTEEGPQCLCPSSG 162
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
R +G C D+DEC + C C NT GS+ C C G++ L+ + Y C
Sbjct: 163 LRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFE-----LQYISGRYDC 217
Query: 524 VDIDECANDPTLC-ENGHCSNTPGGYECDCDVGF 556
+DI+EC D C + +C NT G ++C C G+
Sbjct: 218 IDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 76.2 bits (179), Expect = 3e-13
Identities = 53/158 (33%), Positives = 73/158 (46%), Gaps = 23/158 (14%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQC 460
C G C +G C+C GY+ G C+ D +EC + C C+N GS++C
Sbjct: 69 CKFGEC---VGPNKCRCFPGYT-----GKTCSQDVNECGMKPRPCQHR--CVNTHGSYKC 118
Query: 461 RCRDGWR-GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C G ATC + C N C + +C +T+ +CLC + GLR
Sbjct: 119 FCLSGHMLMPDATCVNSRTCAMIN--C--QYSCEDTEEGPQCLCPSS------GLRLAPN 168
Query: 520 VYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGF 556
C+DIDECA+ +C N C NT G Y C C +GF
Sbjct: 169 GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF 206
Score = 70.5 bits (165), Expect = 1e-11
Identities = 30/82 (36%), Positives = 47/82 (57%), Gaps = 4/82 (4%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD--SKNHTCVDVNECEIVDGVCGD 173
++++ECA+ +C + R C N G + C C G+E S + C+D+NEC + C
Sbjct: 173 LDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSH 232
Query: 174 -GDCHNTEGSFTCHCRPGYKAD 194
+C NT+GSF C C+ GYK +
Sbjct: 233 HANCFNTQGSFKCKCKQGYKGN 254
Score = 33.5 bits (73), Expect = 2.0
Identities = 15/52 (28%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 117 MEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIV 167
+++NEC C H C N G F C C GY+ + + + N + V
Sbjct: 218 IDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEV 269
>AF193055-1|AAG22483.1| 474|Homo sapiens unknown protein.
Length = 474
Score = 109 bits (262), Expect = 3e-23
Identities = 62/163 (38%), Positives = 85/163 (52%), Gaps = 10/163 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC P C H RC N G + C C G+ + TCV+ C +++ C C
Sbjct: 15 DVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHML-MPDATCVNSRTCAMIN--C-QYSCE 69
Query: 178 NTEGSFTCHC-RPGYKADDFSKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMEL 235
+TE C C G + + C+DIDECA +C RCVNT GS+ C+C G EL
Sbjct: 70 DTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFEL 129
Query: 236 --APDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
R C DI+EC++ S CS+ A C N G+++C C +GY
Sbjct: 130 QYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 172
Score = 91.1 bits (216), Expect = 1e-17
Identities = 60/183 (32%), Positives = 82/183 (44%), Gaps = 25/183 (13%)
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
CQH CVNT GSY C C G L D +C + CA C C +T C C
Sbjct: 26 CQHRCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCA--MINCQYS-CEDTEEGPQCLCPS 81
Query: 357 GLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVC 416
+ A + C DIDECA K + P C NT GS+ C
Sbjct: 82 SGLRLAPNGRD-CLDIDECAS-------------GKVICPYNRR------CVNTFGSYYC 121
Query: 417 QCPDGYSVKPEQGPA-CTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCED 475
+C G+ ++ G C D +EC + + C A+C N GSF+C+C+ G++G+G C
Sbjct: 122 KCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSA 181
Query: 476 VDE 478
+ E
Sbjct: 182 IPE 184
Score = 90.6 bits (215), Expect = 1e-17
Identities = 65/193 (33%), Positives = 85/193 (44%), Gaps = 37/193 (19%)
Query: 326 RDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSAAGAKPTCQDIDECADLISTII 383
+D++EC RPC +C NT GSY C C G L+P A TC + CA
Sbjct: 14 QDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA-----TCVNSRTCA------- 60
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD-GYSVKPEQGPACTDDDECELGT 442
++ Q SC +T C CP G + P G C D DEC G
Sbjct: 61 ---------MINCQY-------SCEDTEEGPQCLCPSSGLRLAPN-GRDCLDIDECASGK 103
Query: 443 CDCHPAADCINLPGSFQCRCRDGWR----GDGATCEDVDECLTNNGGCHPRATCANTDGS 498
C C+N GS+ C+C G+ C D++EC ++ C A C NT GS
Sbjct: 104 VICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGS 163
Query: 499 FRCLCDTGYKGDG 511
F+C C GYKG+G
Sbjct: 164 FKCKCKQGYKGNG 176
Score = 86.6 bits (205), Expect = 2e-16
Identities = 49/154 (31%), Positives = 71/154 (46%), Gaps = 15/154 (9%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDG 465
C NT GS+ C C G+ + P+ C + C + C C + QC C G
Sbjct: 30 CVNTHGSYKCFCLSGHMLMPDA--TCVNSRTCAMINCQY----SCEDTEEGPQCLCPSSG 83
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
R +G C D+DEC + C C NT GS+ C C G++ L+ + Y C
Sbjct: 84 LRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFE-----LQYISGRYDC 138
Query: 524 VDIDECANDPTLC-ENGHCSNTPGGYECDCDVGF 556
+DI+EC D C + +C NT G ++C C G+
Sbjct: 139 IDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 172
Score = 86.2 bits (204), Expect = 3e-16
Identities = 59/181 (32%), Positives = 80/181 (44%), Gaps = 14/181 (7%)
Query: 157 TCV-DVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG 215
TC DVNEC + C C NT GS+ C C G+ CV+ CA + C+
Sbjct: 11 TCSQDVNECGMKPRPC-QHRCVNTHGSYKCFCLSGHMLMP-DATCVNSRTCAMIN--CQY 66
Query: 216 GRCVNTAGSFRCEC-GHGMELAPDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDE 273
C +T +C C G+ LAP+ C DIDEC+ IC N C N G+Y C C
Sbjct: 67 S-CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHI 125
Query: 274 GYAQSTVKSHXXXXXXX--XXXXXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDID 329
G+ + C H +C NT GS+ C C++G+ + +G C I
Sbjct: 126 GFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY--KGNGLRCSAIP 183
Query: 330 E 330
E
Sbjct: 184 E 184
Score = 84.2 bits (199), Expect = 1e-15
Identities = 59/187 (31%), Positives = 79/187 (42%), Gaps = 26/187 (13%)
Query: 239 RLSC-KDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRC 297
R +C +D++EC + C + C N G+Y+C C G+ + C
Sbjct: 9 RETCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHM---LMPDATCVNSRTCAMINC 64
Query: 298 QHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDECAGGARPCG-GGQCRNTVGSYTCTCT 355
Q+SC +T C C G L +GR C DIDECA G C +C NT GSY C C
Sbjct: 65 QYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCH 124
Query: 356 DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFV 415
G + C DI+EC ++D S +C NT GSF
Sbjct: 125 IGFELQYISGRYDCIDINEC----------TMDSHTCS---------HHANCFNTQGSFK 165
Query: 416 CQCPDGY 422
C+C GY
Sbjct: 166 CKCKQGY 172
Score = 81.0 bits (191), Expect = 1e-14
Identities = 54/162 (33%), Positives = 76/162 (46%), Gaps = 11/162 (6%)
Query: 202 DIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACE 261
D++EC C+ RCVNT GS++C C G L PD +C + C++ + C +CE
Sbjct: 15 DVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPD-ATCVNSRTCAMIN--CQY-SCE 69
Query: 262 NQMGTYQCVC-DEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREGWHL 318
+ QC+C G + C ++ CVNT GSY+C C G+ L
Sbjct: 70 DTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFEL 129
Query: 319 R-ADGR-SCRDIDECAGGARPCG-GGQCRNTVGSYTCTCTDG 357
+ GR C DI+EC + C C NT GS+ C C G
Sbjct: 130 QYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG 171
Score = 70.5 bits (165), Expect = 1e-11
Identities = 30/82 (36%), Positives = 47/82 (57%), Gaps = 4/82 (4%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD--SKNHTCVDVNECEIVDGVCGD 173
++++ECA+ +C + R C N G + C C G+E S + C+D+NEC + C
Sbjct: 94 LDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSH 153
Query: 174 -GDCHNTEGSFTCHCRPGYKAD 194
+C NT+GSF C C+ GYK +
Sbjct: 154 HANCFNTQGSFKCKCKQGYKGN 175
Score = 67.3 bits (157), Expect = 1e-10
Identities = 44/128 (34%), Positives = 61/128 (47%), Gaps = 15/128 (11%)
Query: 432 CTDD-DECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDGATCEDVDECLTNNGGCHPR 489
C+ D +EC + C C+N GS++C C G ATC + C N C +
Sbjct: 12 CSQDVNECGMKPRPCQHR--CVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMIN--C--Q 65
Query: 490 ATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCE-NGHCSNTPGGY 548
+C +T+ +CLC + GLR C+DIDECA+ +C N C NT G Y
Sbjct: 66 YSCEDTEEGPQCLCPSS------GLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSY 119
Query: 549 ECDCDVGF 556
C C +GF
Sbjct: 120 YCKCHIGF 127
Score = 33.5 bits (73), Expect = 2.0
Identities = 15/52 (28%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 117 MEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIV 167
+++NEC C H C N G F C C GY+ + + + N + V
Sbjct: 139 IDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEV 190
>AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor
repeat containing protein protein.
Length = 553
Score = 109 bits (262), Expect = 3e-23
Identities = 62/163 (38%), Positives = 85/163 (52%), Gaps = 10/163 (6%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
+VNEC P C H RC N G + C C G+ + TCV+ C +++ C C
Sbjct: 94 DVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHML-MPDATCVNSRTCAMIN--C-QYSCE 148
Query: 178 NTEGSFTCHC-RPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMEL 235
+TE C C G + + C+DIDECA +C RCVNT GS+ C+C G EL
Sbjct: 149 DTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFEL 208
Query: 236 A--PDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
R C DI+EC++ S CS+ A C N G+++C C +GY
Sbjct: 209 QYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 100 bits (239), Expect = 2e-20
Identities = 73/219 (33%), Positives = 95/219 (43%), Gaps = 22/219 (10%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCV-DVNECEIVDGVCGDGDCH 177
V E PG C G C +G C CFPGY TC DVNEC + C C
Sbjct: 60 VCEATCEPG-CKFGEC---VGPNKCRCFPGYT----GKTCSQDVNECGMKPRPC-QHRCV 110
Query: 178 NTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCEC-GHGMELA 236
NT GS+ C C G+ CV+ CA + C+ C +T +C C G+ LA
Sbjct: 111 NTHGSYKCFCLSGHMLMP-DATCVNSRTCAMIN--CQYS-CEDTEEGPQCLCPSSGLRLA 166
Query: 237 PDRLSCKDIDECSITSGICS-NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXX--XXX 293
P+ C DIDEC+ IC N C N G+Y C C G+ +
Sbjct: 167 PNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMD 226
Query: 294 XXRCQH--SCVNTPGSYHCTCREGWHLRADGRSCRDIDE 330
C H +C NT GS+ C C++G+ + +G C I E
Sbjct: 227 SHTCSHHANCFNTQGSFKCKCKQGY--KGNGLRCSAIPE 263
Score = 97.5 bits (232), Expect = 1e-19
Identities = 78/254 (30%), Positives = 108/254 (42%), Gaps = 35/254 (13%)
Query: 229 CGHGMELAPD---RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXX 285
C +G +LA R + K + E + G C G C +G +C C GY T K+
Sbjct: 41 CHYGTKLACCYGWRRNSKGVCEATCEPG-CKFGEC---VGPNKCRCFPGY---TGKTCSQ 93
Query: 286 XXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCRN 345
CQH CVNT GSY C C G L D +C + CA C C +
Sbjct: 94 DVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCA--MINCQYS-CED 149
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
T C C + A + C DIDECA K + P
Sbjct: 150 TEEGPQCLCPSSGLRLAPNGRD-CLDIDECAS-------------GKVICPYNRR----- 190
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPA-CTDDDECELGTCDCHPAADCINLPGSFQCRCRD 464
C NT GS+ C+C G+ ++ G C D +EC + + C A+C N GSF+C+C+
Sbjct: 191 -CVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQ 249
Query: 465 GWRGDGATCEDVDE 478
G++G+G C + E
Sbjct: 250 GYKGNGLRCSAIPE 263
Score = 95.5 bits (227), Expect = 4e-19
Identities = 71/214 (33%), Positives = 94/214 (43%), Gaps = 42/214 (19%)
Query: 306 GSYHCTCREGWHLRADGRSC-RDIDECAGGARPCGGGQCRNTVGSYTCTCTDG--LVPSA 362
G C C G+ G++C +D++EC RPC +C NT GSY C C G L+P A
Sbjct: 76 GPNKCRCFPGY----TGKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA 130
Query: 363 AGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPD-G 421
TC + CA ++ Q SC +T C CP G
Sbjct: 131 -----TCVNSRTCA----------------MINCQY-------SCEDTEEGPQCLCPSSG 162
Query: 422 YSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR----GDGATCEDVD 477
+ P G C D DEC G C C+N GS+ C+C G+ C D++
Sbjct: 163 LRLAPN-GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 478 ECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDG 511
EC ++ C A C NT GSF+C C GYKG+G
Sbjct: 222 ECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNG 255
Score = 91.5 bits (217), Expect = 7e-18
Identities = 71/219 (32%), Positives = 98/219 (44%), Gaps = 23/219 (10%)
Query: 145 CFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDID 204
C G+ ++SK V E G C G+C G C C PGY S+ D++
Sbjct: 49 CCYGWRRNSKG-----VCEATCEPG-CKFGEC---VGPNKCRCFPGYTGKTCSQ---DVN 96
Query: 205 ECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQM 264
EC C+ RCVNT GS++C C G L PD +C + C++ + C +CE+
Sbjct: 97 ECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCAMIN--CQY-SCEDTE 151
Query: 265 GTYQCVC-DEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREGWHLR-A 320
QC+C G + C ++ CVNT GSY+C C G+ L+
Sbjct: 152 EGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYI 211
Query: 321 DGR-SCRDIDECAGGARPCGG-GQCRNTVGSYTCTCTDG 357
GR C DI+EC + C C NT GS+ C C G
Sbjct: 212 SGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG 250
Score = 90.2 bits (214), Expect = 2e-17
Identities = 65/212 (30%), Positives = 87/212 (41%), Gaps = 31/212 (14%)
Query: 213 CRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCD 272
C+ G CV G +C C G + +D++EC + C + C N G+Y+C C
Sbjct: 69 CKFGECV---GPNKCRCFPGYT---GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCL 121
Query: 273 EGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTC-REGWHLRADGRSCRDIDEC 331
G+ + CQ+SC +T C C G L +GR C DIDEC
Sbjct: 122 SGHM---LMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDEC 178
Query: 332 AGGARPCG-GGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
A G C +C NT GSY C C G + C DI+EC ++D
Sbjct: 179 ASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC----------TMDSH 228
Query: 391 QKSVDPQIPELCGAGSCHNTIGSFVCQCPDGY 422
S +C NT GSF C+C GY
Sbjct: 229 TCS---------HHANCFNTQGSFKCKCKQGY 251
Score = 86.6 bits (205), Expect = 2e-16
Identities = 49/154 (31%), Positives = 71/154 (46%), Gaps = 15/154 (9%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRC-RDG 465
C NT GS+ C C G+ + P+ C + C + C C + QC C G
Sbjct: 109 CVNTHGSYKCFCLSGHMLMPDA--TCVNSRTCAMINCQY----SCEDTEEGPQCLCPSSG 162
Query: 466 WR--GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSC 523
R +G C D+DEC + C C NT GS+ C C G++ L+ + Y C
Sbjct: 163 LRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFE-----LQYISGRYDC 217
Query: 524 VDIDECANDPTLC-ENGHCSNTPGGYECDCDVGF 556
+DI+EC D C + +C NT G ++C C G+
Sbjct: 218 IDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 76.2 bits (179), Expect = 3e-13
Identities = 53/158 (33%), Positives = 73/158 (46%), Gaps = 23/158 (14%)
Query: 402 CGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQC 460
C G C +G C+C GY+ G C+ D +EC + C C+N GS++C
Sbjct: 69 CKFGEC---VGPNKCRCFPGYT-----GKTCSQDVNECGMKPRPCQHR--CVNTHGSYKC 118
Query: 461 RCRDGWR-GDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCC 519
C G ATC + C N C + +C +T+ +CLC + GLR
Sbjct: 119 FCLSGHMLMPDATCVNSRTCAMIN--C--QYSCEDTEEGPQCLCPSS------GLRLAPN 168
Query: 520 VYSCVDIDECANDPTLCE-NGHCSNTPGGYECDCDVGF 556
C+DIDECA+ +C N C NT G Y C C +GF
Sbjct: 169 GRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF 206
Score = 70.5 bits (165), Expect = 1e-11
Identities = 30/82 (36%), Positives = 47/82 (57%), Gaps = 4/82 (4%)
Query: 117 MEVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD--SKNHTCVDVNECEIVDGVCGD 173
++++ECA+ +C + R C N G + C C G+E S + C+D+NEC + C
Sbjct: 173 LDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSH 232
Query: 174 -GDCHNTEGSFTCHCRPGYKAD 194
+C NT+GSF C C+ GYK +
Sbjct: 233 HANCFNTQGSFKCKCKQGYKGN 254
Score = 33.5 bits (73), Expect = 2.0
Identities = 15/52 (28%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 117 MEVNECAAFPGLCGH-GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIV 167
+++NEC C H C N G F C C GY+ + + + N + V
Sbjct: 218 IDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEV 269
>AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precursor
protein.
Length = 1406
Score = 109 bits (261), Expect = 3e-23
Identities = 114/417 (27%), Positives = 169/417 (40%), Gaps = 75/417 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGF--------TCDCFPGYEKDSKNHTC-VDVNECEIVDGVCG 172
C G CG C++ GG C C GY C +D +EC C
Sbjct: 107 CETTIGSCGKNSCQH--GGICHQDPIYPVCICPAGYA----GRFCEIDHDEC--ASSPCQ 158
Query: 173 DGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
+G C + ++C C PGY+ +++DECA +D C+N G + C C H
Sbjct: 159 NGAVCQDGIDGYSCFCVPGYQGRHCD---LEVDECA-SDPCKNEATCLNEIGRYTCICPH 214
Query: 232 GMELAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
++C+ +IDEC S C NGA C++ +G Y C C G+ + +
Sbjct: 215 NYS----GVNCELEIDEC--WSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECAS 268
Query: 290 XXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQCRNT 346
C H CV+ Y C C G C + ++PC C ++
Sbjct: 269 QP-----CLHGGLCVDGENRYSCNCTGSGFT---GTHCETLMPLCW-SKPCHNNATCEDS 319
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
V +YTC C P GA+ C+ D++EC S + + ++ S + Q + G
Sbjct: 320 VDNYTCHCW----PGYTGAQ--CEIDLNECN---SNPCQSNGECVELSSEKQYGRITGLP 370
Query: 406 SC--HNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
S ++ +VC C G++ G C +D +EC C C NLPG++ C C
Sbjct: 371 SSFSYHEASGYVCICQPGFT-----GIHCEEDVNECSSNPCQ--NGGTCENLPGNYTCHC 423
Query: 463 R-DGWRG---DGATCEDV------DECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
D G C D+ +CL NNG C P + F CLC +GY G
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCL-NNGTCIPH--FQDGQHGFSCLCPSGYTG 477
Score = 97.9 bits (233), Expect = 8e-20
Identities = 118/433 (27%), Positives = 165/433 (38%), Gaps = 84/433 (19%)
Query: 172 GDGDCHNTEG--SFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCE 228
G C NT G SF C C PGY IC I C N GG C C
Sbjct: 81 GSATCVNTPGERSFLCKCPPGYS----GTICETTIGSCGKNSCQ-HGGICHQDPIYPVCI 135
Query: 229 CGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXX 287
C G R D DEC+ S C NGA C++ + Y C C GY +
Sbjct: 136 CPAGY---AGRFCEIDHDECA--SSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEV 187
Query: 288 XXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRN 345
+ + +C+N G Y C C + G +C +IDEC ++PC G C++
Sbjct: 188 DECASDPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDEC--WSQPCLNGATCQD 241
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVD-ELQKSVD-------- 395
+G+Y C C G + C+ + DECA + VD E + S +
Sbjct: 242 ALGAYFCDCAPGFLGD------HCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTG 295
Query: 396 ---PQIPELCGAGSCHN------TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
+ LC + CHN ++ ++ C C GY+ G C D +EC C
Sbjct: 296 THCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYT-----GAQCEIDLNECNSNPCQS 350
Query: 446 HPAADCI------------NLPGSFQ--------CRCRDGWRGDGATCEDVDECLTNNGG 485
+ +C+ LP SF C C+ G+ G EDV+EC +N
Sbjct: 351 N--GECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCE-EDVNECSSN--P 405
Query: 486 CHPRATCANTDGSFRCLCD-TGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNT 544
C TC N G++ C C YG R + +C N+ T H +
Sbjct: 406 CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIP--HFQDG 463
Query: 545 PGGYECDCDVGFT 557
G+ C C G+T
Sbjct: 464 QHGFSCLCPSGYT 476
Score = 72.9 bits (171), Expect = 3e-12
Identities = 84/281 (29%), Positives = 119/281 (42%), Gaps = 45/281 (16%)
Query: 297 CQHS--CVNTPGSYHCTCREGWHLRADGRSCRDI-DECAGGARPC-GGGQCRNTVG--SY 350
CQ++ C + C+C + + D + C ++ D C + PC G C NT G S+
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTAN-NLD-KDCDNMKDPCF--SNPCQGSATCVNTPGERSF 94
Query: 351 TCTCTDG----LVPSAAGA--KPTCQDIDEC-ADLISTIIMMSVDELQKSVDPQIPELCG 403
C C G + + G+ K +CQ C D I + + + + E C
Sbjct: 95 LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDE-CA 153
Query: 404 AGSCHNTIGSFVCQCP-DGYS---VKPEQGPACT-DDDECELGTCDCHPAADCINLPGSF 458
+ C N VCQ DGYS V QG C + DEC + C A C+N G +
Sbjct: 154 SSPCQN---GAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--ASDPCKNEATCLNEIGRY 208
Query: 459 QCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C C + G CE ++DEC + C ATC + G++ C C G+ GD L T
Sbjct: 209 TCICPHNY--SGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCELNT- 263
Query: 518 CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDC-DVGFT 557
DECA+ P L G C + Y C+C GFT
Sbjct: 264 ---------DECASQPCL-HGGLCVDGENRYSCNCTGSGFT 294
Score = 72.1 bits (169), Expect = 5e-12
Identities = 98/369 (26%), Positives = 138/369 (37%), Gaps = 76/369 (20%)
Query: 206 CADNDALCRGGRCVN--TAGSFR----CECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C N+ C C N T F C C D+ C ++ + ++ +
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNL-DK-DCDNMKDPCFSNPCQGSAT 84
Query: 260 CENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREG 315
C N G ++ C C GY+ + ++ CQH C P C C G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICET-----TIGSCGKNSCQHGGICHQDPIYPVCICPAG 139
Query: 316 WHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DI 372
+ GR C D DECA PC G C++ + Y+C C VP G C ++
Sbjct: 140 YA----GRFCEIDHDECASS--PCQNGAVCQDGIDGYSCFC----VPGYQGRH--CDLEV 187
Query: 373 DECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC 432
DECA DP E +C N IG + C CP YS G C
Sbjct: 188 DECAS-----------------DPCKNE----ATCLNEIGRYTCICPHNYS-----GVNC 221
Query: 433 T-DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRA 490
+ DEC + C A C + G++ C C G+ GD CE + DEC + C
Sbjct: 222 ELEIDEC--WSQPCLNGATCQDALGAYFCDCAPGFLGDH--CELNTDECASQP--CLHGG 275
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYEC 550
C + + + C C TG G T+ + C + P N C ++ Y C
Sbjct: 276 LCVDGENRYSCNC-TGSGFTGTHCETLMPL--------CWSKPCH-NNATCEDSVDNYTC 325
Query: 551 DCDVGFTRA 559
C G+T A
Sbjct: 326 HCWPGYTGA 334
Score = 72.1 bits (169), Expect = 5e-12
Identities = 60/220 (27%), Positives = 88/220 (40%), Gaps = 43/220 (19%)
Query: 297 CQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCT 353
C H +C + SYHC+C GW G+ C +IDEC + PC G C + V +Y CT
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECF--SNPCIHGNCSDRVAAYHCT 1201
Query: 354 CTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C P G C+ DID C Q + +C +
Sbjct: 1202 CE----PGYTGVN--CEVDIDNC---------------------QSHQCANGATCISHTN 1234
Query: 413 SFVCQCPDGYSVK-PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
+ C C ++ K Q + E C+ +C +C CR G+ G+
Sbjct: 1235 GYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEW- 1293
Query: 472 TCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
CE D+DEC ++ C C + F+CLCD + G+
Sbjct: 1294 -CEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFAGE 1330
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/166 (26%), Positives = 73/166 (43%), Gaps = 17/166 (10%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG- 174
++ ++EC + P C HG C + + + C C PGY + + VD++ C+ C +G
Sbjct: 1175 ELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGY---TGVNCEVDIDNCQ--SHQCANGA 1227
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECAD---NDALCRGGRCVNTAGSFRCECGH 231
C + ++C C + + + C + N GG C +C C
Sbjct: 1228 TCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP 1287
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYA 276
G KDIDEC+ S C NG C++ + +QC+CD +A
Sbjct: 1288 GF---TGEWCEKDIDECA--SDPCVNGGLCQDLLNKFQCLCDVAFA 1328
Score = 63.3 bits (147), Expect = 2e-09
Identities = 61/239 (25%), Positives = 91/239 (38%), Gaps = 55/239 (23%)
Query: 325 CRDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
C ++ C + PC GG C + SY C+C P K +IDEC
Sbjct: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSC-----PLGWSGKHCELNIDECFS------ 1183
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGT 442
+P C G+C + + ++ C C GY+ G C D D C+ +
Sbjct: 1184 -----------NP-----CIHGNCSDRVAAYHCTCEPGYT-----GVNCEVDIDNCQ--S 1220
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGG----CHPRATCANTDGS 498
C A CI+ + C C + G + + N C+ C
Sbjct: 1221 HQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTE 1280
Query: 499 FRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
+C+C G+ G+ + DIDECA+DP C NG C + ++C CDV F
Sbjct: 1281 LKCMCRPGFTGE----------WCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAF 1327
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 25/173 (14%)
Query: 390 LQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPA 448
LQ +V P L G G+C + S+ C CP G+S G C + DEC C H
Sbjct: 1138 LQLNVCNSNPCLHG-GNCEDIYSSYHCSCPLGWS-----GKHCELNIDECFSNPC-IH-- 1188
Query: 449 ADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
+C + ++ C C G+ G CE D+D C ++ C ATC + + CLC +
Sbjct: 1189 GNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNF 1244
Query: 508 KGDGYGLRTVCCVYSCVDIDECANDPT--LCEN-GHCSNTPGGYECDCDVGFT 557
G C S + C N+ T C N G+C+ +C C GFT
Sbjct: 1245 TGK-------FCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Score = 52.4 bits (120), Expect = 4e-06
Identities = 46/184 (25%), Positives = 65/184 (35%), Gaps = 25/184 (13%)
Query: 200 CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C+ ++ C N L GG C + S+ C C G L +IDEC S C +G
Sbjct: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWSGKHCEL---NIDEC--FSNPCIHGN 1190
Query: 260 CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
C +++ Y C C+ GY + +C++ Y C C +
Sbjct: 1191 CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGA---TCISHTNGYSCLCFGNF--- 1244
Query: 320 ADGRSCRDI---DECAGGAR---PC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDI 372
G+ CR G + C GG C C C G +DI
Sbjct: 1245 -TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE-----KDI 1298
Query: 373 DECA 376
DECA
Sbjct: 1299 DECA 1302
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 14/85 (16%)
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C ++ C N+ C C + S+ C C G+ G L +IDEC ++
Sbjct: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL----------NIDECFSN 1184
Query: 533 PTLCENGHCSNTPGGYECDCDVGFT 557
P C +G+CS+ Y C C+ G+T
Sbjct: 1185 P--CIHGNCSDRVAAYHCTCEPGYT 1207
>AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precursor
protein.
Length = 1376
Score = 109 bits (261), Expect = 3e-23
Identities = 114/417 (27%), Positives = 169/417 (40%), Gaps = 75/417 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGF--------TCDCFPGYEKDSKNHTC-VDVNECEIVDGVCG 172
C G CG C++ GG C C GY C +D +EC C
Sbjct: 107 CETTIGSCGKNSCQH--GGICHQDPIYPVCICPAGYA----GRFCEIDHDEC--ASSPCQ 158
Query: 173 DGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
+G C + ++C C PGY+ +++DECA +D C+N G + C C H
Sbjct: 159 NGAVCQDGIDGYSCFCVPGYQGRHCD---LEVDECA-SDPCKNEATCLNEIGRYTCICPH 214
Query: 232 GMELAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
++C+ +IDEC S C NGA C++ +G Y C C G+ + +
Sbjct: 215 NYS----GVNCELEIDEC--WSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECAS 268
Query: 290 XXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQCRNT 346
C H CV+ Y C C G C + ++PC C ++
Sbjct: 269 QP-----CLHGGLCVDGENRYSCNCTGSGFT---GTHCETLMPLCW-SKPCHNNATCEDS 319
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
V +YTC C P GA+ C+ D++EC S + + ++ S + Q + G
Sbjct: 320 VDNYTCHCW----PGYTGAQ--CEIDLNECN---SNPCQSNGECVELSSEKQYGRITGLP 370
Query: 406 SC--HNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
S ++ +VC C G++ G C +D +EC C C NLPG++ C C
Sbjct: 371 SSFSYHEASGYVCICQPGFT-----GIHCEEDVNECSSNPCQ--NGGTCENLPGNYTCHC 423
Query: 463 R-DGWRG---DGATCEDV------DECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
D G C D+ +CL NNG C P + F CLC +GY G
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCL-NNGTCIPH--FQDGQHGFSCLCPSGYTG 477
Score = 97.9 bits (233), Expect = 8e-20
Identities = 118/433 (27%), Positives = 165/433 (38%), Gaps = 84/433 (19%)
Query: 172 GDGDCHNTEG--SFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCE 228
G C NT G SF C C PGY IC I C N GG C C
Sbjct: 81 GSATCVNTPGERSFLCKCPPGYS----GTICETTIGSCGKNSCQ-HGGICHQDPIYPVCI 135
Query: 229 CGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXX 287
C G R D DEC+ S C NGA C++ + Y C C GY +
Sbjct: 136 CPAGY---AGRFCEIDHDECA--SSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEV 187
Query: 288 XXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRN 345
+ + +C+N G Y C C + G +C +IDEC ++PC G C++
Sbjct: 188 DECASDPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDEC--WSQPCLNGATCQD 241
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVD-ELQKSVD-------- 395
+G+Y C C G + C+ + DECA + VD E + S +
Sbjct: 242 ALGAYFCDCAPGFLGD------HCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTG 295
Query: 396 ---PQIPELCGAGSCHN------TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
+ LC + CHN ++ ++ C C GY+ G C D +EC C
Sbjct: 296 THCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYT-----GAQCEIDLNECNSNPCQS 350
Query: 446 HPAADCI------------NLPGSFQ--------CRCRDGWRGDGATCEDVDECLTNNGG 485
+ +C+ LP SF C C+ G+ G EDV+EC +N
Sbjct: 351 N--GECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCE-EDVNECSSN--P 405
Query: 486 CHPRATCANTDGSFRCLCD-TGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNT 544
C TC N G++ C C YG R + +C N+ T H +
Sbjct: 406 CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIP--HFQDG 463
Query: 545 PGGYECDCDVGFT 557
G+ C C G+T
Sbjct: 464 QHGFSCLCPSGYT 476
Score = 72.9 bits (171), Expect = 3e-12
Identities = 84/281 (29%), Positives = 119/281 (42%), Gaps = 45/281 (16%)
Query: 297 CQHS--CVNTPGSYHCTCREGWHLRADGRSCRDI-DECAGGARPC-GGGQCRNTVG--SY 350
CQ++ C + C+C + + D + C ++ D C + PC G C NT G S+
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTAN-NLD-KDCDNMKDPCF--SNPCQGSATCVNTPGERSF 94
Query: 351 TCTCTDG----LVPSAAGA--KPTCQDIDEC-ADLISTIIMMSVDELQKSVDPQIPELCG 403
C C G + + G+ K +CQ C D I + + + + E C
Sbjct: 95 LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDE-CA 153
Query: 404 AGSCHNTIGSFVCQCP-DGYS---VKPEQGPACT-DDDECELGTCDCHPAADCINLPGSF 458
+ C N VCQ DGYS V QG C + DEC + C A C+N G +
Sbjct: 154 SSPCQN---GAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--ASDPCKNEATCLNEIGRY 208
Query: 459 QCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C C + G CE ++DEC + C ATC + G++ C C G+ GD L T
Sbjct: 209 TCICPHNY--SGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCELNT- 263
Query: 518 CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDC-DVGFT 557
DECA+ P L G C + Y C+C GFT
Sbjct: 264 ---------DECASQPCL-HGGLCVDGENRYSCNCTGSGFT 294
Score = 72.1 bits (169), Expect = 5e-12
Identities = 98/369 (26%), Positives = 138/369 (37%), Gaps = 76/369 (20%)
Query: 206 CADNDALCRGGRCVN--TAGSFR----CECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C N+ C C N T F C C D+ C ++ + ++ +
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNL-DK-DCDNMKDPCFSNPCQGSAT 84
Query: 260 CENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREG 315
C N G ++ C C GY+ + ++ CQH C P C C G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICET-----TIGSCGKNSCQHGGICHQDPIYPVCICPAG 139
Query: 316 WHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DI 372
+ GR C D DECA PC G C++ + Y+C C VP G C ++
Sbjct: 140 YA----GRFCEIDHDECASS--PCQNGAVCQDGIDGYSCFC----VPGYQGRH--CDLEV 187
Query: 373 DECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC 432
DECA DP E +C N IG + C CP YS G C
Sbjct: 188 DECAS-----------------DPCKNE----ATCLNEIGRYTCICPHNYS-----GVNC 221
Query: 433 T-DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRA 490
+ DEC + C A C + G++ C C G+ GD CE + DEC + C
Sbjct: 222 ELEIDEC--WSQPCLNGATCQDALGAYFCDCAPGFLGDH--CELNTDECASQP--CLHGG 275
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYEC 550
C + + + C C TG G T+ + C + P N C ++ Y C
Sbjct: 276 LCVDGENRYSCNC-TGSGFTGTHCETLMPL--------CWSKPCH-NNATCEDSVDNYTC 325
Query: 551 DCDVGFTRA 559
C G+T A
Sbjct: 326 HCWPGYTGA 334
Score = 72.1 bits (169), Expect = 5e-12
Identities = 60/220 (27%), Positives = 88/220 (40%), Gaps = 43/220 (19%)
Query: 297 CQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCT 353
C H +C + SYHC+C GW G+ C +IDEC + PC G C + V +Y CT
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECF--SNPCIHGNCSDRVAAYHCT 1201
Query: 354 CTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C P G C+ DID C Q + +C +
Sbjct: 1202 CE----PGYTGVN--CEVDIDNC---------------------QSHQCANGATCISHTN 1234
Query: 413 SFVCQCPDGYSVK-PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
+ C C ++ K Q + E C+ +C +C CR G+ G+
Sbjct: 1235 GYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEW- 1293
Query: 472 TCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
CE D+DEC ++ C C + F+CLCD + G+
Sbjct: 1294 -CEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFAGE 1330
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/166 (26%), Positives = 73/166 (43%), Gaps = 17/166 (10%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG- 174
++ ++EC + P C HG C + + + C C PGY + + VD++ C+ C +G
Sbjct: 1175 ELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGY---TGVNCEVDIDNCQ--SHQCANGA 1227
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECAD---NDALCRGGRCVNTAGSFRCECGH 231
C + ++C C + + + C + N GG C +C C
Sbjct: 1228 TCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP 1287
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYA 276
G KDIDEC+ S C NG C++ + +QC+CD +A
Sbjct: 1288 GF---TGEWCEKDIDECA--SDPCVNGGLCQDLLNKFQCLCDVAFA 1328
Score = 63.3 bits (147), Expect = 2e-09
Identities = 61/239 (25%), Positives = 91/239 (38%), Gaps = 55/239 (23%)
Query: 325 CRDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
C ++ C + PC GG C + SY C+C P K +IDEC
Sbjct: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSC-----PLGWSGKHCELNIDECFS------ 1183
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGT 442
+P C G+C + + ++ C C GY+ G C D D C+ +
Sbjct: 1184 -----------NP-----CIHGNCSDRVAAYHCTCEPGYT-----GVNCEVDIDNCQ--S 1220
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGG----CHPRATCANTDGS 498
C A CI+ + C C + G + + N C+ C
Sbjct: 1221 HQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTE 1280
Query: 499 FRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
+C+C G+ G+ + DIDECA+DP C NG C + ++C CDV F
Sbjct: 1281 LKCMCRPGFTGE----------WCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAF 1327
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 25/173 (14%)
Query: 390 LQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPA 448
LQ +V P L G G+C + S+ C CP G+S G C + DEC C H
Sbjct: 1138 LQLNVCNSNPCLHG-GNCEDIYSSYHCSCPLGWS-----GKHCELNIDECFSNPC-IH-- 1188
Query: 449 ADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
+C + ++ C C G+ G CE D+D C ++ C ATC + + CLC +
Sbjct: 1189 GNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNF 1244
Query: 508 KGDGYGLRTVCCVYSCVDIDECANDPT--LCEN-GHCSNTPGGYECDCDVGFT 557
G C S + C N+ T C N G+C+ +C C GFT
Sbjct: 1245 TGK-------FCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Score = 52.4 bits (120), Expect = 4e-06
Identities = 46/184 (25%), Positives = 65/184 (35%), Gaps = 25/184 (13%)
Query: 200 CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C+ ++ C N L GG C + S+ C C G L +IDEC S C +G
Sbjct: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWSGKHCEL---NIDEC--FSNPCIHGN 1190
Query: 260 CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
C +++ Y C C+ GY + +C++ Y C C +
Sbjct: 1191 CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGA---TCISHTNGYSCLCFGNF--- 1244
Query: 320 ADGRSCRDI---DECAGGAR---PC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDI 372
G+ CR G + C GG C C C G +DI
Sbjct: 1245 -TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE-----KDI 1298
Query: 373 DECA 376
DECA
Sbjct: 1299 DECA 1302
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 14/85 (16%)
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C ++ C N+ C C + S+ C C G+ G L +IDEC ++
Sbjct: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL----------NIDECFSN 1184
Query: 533 PTLCENGHCSNTPGGYECDCDVGFT 557
P C +G+CS+ Y C C+ G+T
Sbjct: 1185 P--CIHGNCSDRVAAYHCTCEPGYT 1207
>AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 109 bits (261), Expect = 3e-23
Identities = 114/417 (27%), Positives = 169/417 (40%), Gaps = 75/417 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGF--------TCDCFPGYEKDSKNHTC-VDVNECEIVDGVCG 172
C G CG C++ GG C C GY C +D +EC C
Sbjct: 107 CETTIGSCGKNSCQH--GGICHQDPIYPVCICPAGYA----GRFCEIDHDEC--ASSPCQ 158
Query: 173 DGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
+G C + ++C C PGY+ +++DECA +D C+N G + C C H
Sbjct: 159 NGAVCQDGIDGYSCFCVPGYQGRHCD---LEVDECA-SDPCKNEATCLNEIGRYTCICPH 214
Query: 232 GMELAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
++C+ +IDEC S C NGA C++ +G Y C C G+ + +
Sbjct: 215 NYS----GVNCELEIDEC--WSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECAS 268
Query: 290 XXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQCRNT 346
C H CV+ Y C C G C + ++PC C ++
Sbjct: 269 QP-----CLHGGLCVDGENRYSCNCTGSGFT---GTHCETLMPLCW-SKPCHNNATCEDS 319
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
V +YTC C P GA+ C+ D++EC S + + ++ S + Q + G
Sbjct: 320 VDNYTCHCW----PGYTGAQ--CEIDLNECN---SNPCQSNGECVELSSEKQYGRITGLP 370
Query: 406 SC--HNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
S ++ +VC C G++ G C +D +EC C C NLPG++ C C
Sbjct: 371 SSFSYHEASGYVCICQPGFT-----GIHCEEDVNECSSNPCQ--NGGTCENLPGNYTCHC 423
Query: 463 R-DGWRG---DGATCEDV------DECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
D G C D+ +CL NNG C P + F CLC +GY G
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCL-NNGTCIPH--FQDGQHGFSCLCPSGYTG 477
Score = 97.9 bits (233), Expect = 8e-20
Identities = 118/433 (27%), Positives = 165/433 (38%), Gaps = 84/433 (19%)
Query: 172 GDGDCHNTEG--SFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCE 228
G C NT G SF C C PGY IC I C N GG C C
Sbjct: 81 GSATCVNTPGERSFLCKCPPGYS----GTICETTIGSCGKNSCQ-HGGICHQDPIYPVCI 135
Query: 229 CGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXX 287
C G R D DEC+ S C NGA C++ + Y C C GY +
Sbjct: 136 CPAGY---AGRFCEIDHDECA--SSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEV 187
Query: 288 XXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRN 345
+ + +C+N G Y C C + G +C +IDEC ++PC G C++
Sbjct: 188 DECASDPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDEC--WSQPCLNGATCQD 241
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVD-ELQKSVD-------- 395
+G+Y C C G + C+ + DECA + VD E + S +
Sbjct: 242 ALGAYFCDCAPGFLGD------HCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTG 295
Query: 396 ---PQIPELCGAGSCHN------TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
+ LC + CHN ++ ++ C C GY+ G C D +EC C
Sbjct: 296 THCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYT-----GAQCEIDLNECNSNPCQS 350
Query: 446 HPAADCI------------NLPGSFQ--------CRCRDGWRGDGATCEDVDECLTNNGG 485
+ +C+ LP SF C C+ G+ G EDV+EC +N
Sbjct: 351 N--GECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCE-EDVNECSSN--P 405
Query: 486 CHPRATCANTDGSFRCLCD-TGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNT 544
C TC N G++ C C YG R + +C N+ T H +
Sbjct: 406 CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIP--HFQDG 463
Query: 545 PGGYECDCDVGFT 557
G+ C C G+T
Sbjct: 464 QHGFSCLCPSGYT 476
Score = 72.9 bits (171), Expect = 3e-12
Identities = 84/281 (29%), Positives = 119/281 (42%), Gaps = 45/281 (16%)
Query: 297 CQHS--CVNTPGSYHCTCREGWHLRADGRSCRDI-DECAGGARPC-GGGQCRNTVG--SY 350
CQ++ C + C+C + + D + C ++ D C + PC G C NT G S+
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTAN-NLD-KDCDNMKDPCF--SNPCQGSATCVNTPGERSF 94
Query: 351 TCTCTDG----LVPSAAGA--KPTCQDIDEC-ADLISTIIMMSVDELQKSVDPQIPELCG 403
C C G + + G+ K +CQ C D I + + + + E C
Sbjct: 95 LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDE-CA 153
Query: 404 AGSCHNTIGSFVCQCP-DGYS---VKPEQGPACT-DDDECELGTCDCHPAADCINLPGSF 458
+ C N VCQ DGYS V QG C + DEC + C A C+N G +
Sbjct: 154 SSPCQN---GAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--ASDPCKNEATCLNEIGRY 208
Query: 459 QCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C C + G CE ++DEC + C ATC + G++ C C G+ GD L T
Sbjct: 209 TCICPHNY--SGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCELNT- 263
Query: 518 CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDC-DVGFT 557
DECA+ P L G C + Y C+C GFT
Sbjct: 264 ---------DECASQPCL-HGGLCVDGENRYSCNCTGSGFT 294
Score = 72.1 bits (169), Expect = 5e-12
Identities = 98/369 (26%), Positives = 138/369 (37%), Gaps = 76/369 (20%)
Query: 206 CADNDALCRGGRCVN--TAGSFR----CECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C N+ C C N T F C C D+ C ++ + ++ +
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNL-DK-DCDNMKDPCFSNPCQGSAT 84
Query: 260 CENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREG 315
C N G ++ C C GY+ + ++ CQH C P C C G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICET-----TIGSCGKNSCQHGGICHQDPIYPVCICPAG 139
Query: 316 WHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DI 372
+ GR C D DECA PC G C++ + Y+C C VP G C ++
Sbjct: 140 YA----GRFCEIDHDECASS--PCQNGAVCQDGIDGYSCFC----VPGYQGRH--CDLEV 187
Query: 373 DECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC 432
DECA DP E +C N IG + C CP YS G C
Sbjct: 188 DECAS-----------------DPCKNE----ATCLNEIGRYTCICPHNYS-----GVNC 221
Query: 433 T-DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRA 490
+ DEC + C A C + G++ C C G+ GD CE + DEC + C
Sbjct: 222 ELEIDEC--WSQPCLNGATCQDALGAYFCDCAPGFLGDH--CELNTDECASQP--CLHGG 275
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYEC 550
C + + + C C TG G T+ + C + P N C ++ Y C
Sbjct: 276 LCVDGENRYSCNC-TGSGFTGTHCETLMPL--------CWSKPCH-NNATCEDSVDNYTC 325
Query: 551 DCDVGFTRA 559
C G+T A
Sbjct: 326 HCWPGYTGA 334
Score = 72.1 bits (169), Expect = 5e-12
Identities = 60/220 (27%), Positives = 88/220 (40%), Gaps = 43/220 (19%)
Query: 297 CQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCT 353
C H +C + SYHC+C GW G+ C +IDEC + PC G C + V +Y CT
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECF--SNPCIHGNCSDRVAAYHCT 1201
Query: 354 CTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C P G C+ DID C Q + +C +
Sbjct: 1202 CE----PGYTGVN--CEVDIDNC---------------------QSHQCANGATCISHTN 1234
Query: 413 SFVCQCPDGYSVK-PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
+ C C ++ K Q + E C+ +C +C CR G+ G+
Sbjct: 1235 GYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEW- 1293
Query: 472 TCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
CE D+DEC ++ C C + F+CLCD + G+
Sbjct: 1294 -CEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFAGE 1330
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/166 (26%), Positives = 73/166 (43%), Gaps = 17/166 (10%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG- 174
++ ++EC + P C HG C + + + C C PGY + + VD++ C+ C +G
Sbjct: 1175 ELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGY---TGVNCEVDIDNCQ--SHQCANGA 1227
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECAD---NDALCRGGRCVNTAGSFRCECGH 231
C + ++C C + + + C + N GG C +C C
Sbjct: 1228 TCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP 1287
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYA 276
G KDIDEC+ S C NG C++ + +QC+CD +A
Sbjct: 1288 GF---TGEWCEKDIDECA--SDPCVNGGLCQDLLNKFQCLCDVAFA 1328
Score = 63.3 bits (147), Expect = 2e-09
Identities = 61/239 (25%), Positives = 91/239 (38%), Gaps = 55/239 (23%)
Query: 325 CRDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
C ++ C + PC GG C + SY C+C P K +IDEC
Sbjct: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSC-----PLGWSGKHCELNIDECFS------ 1183
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGT 442
+P C G+C + + ++ C C GY+ G C D D C+ +
Sbjct: 1184 -----------NP-----CIHGNCSDRVAAYHCTCEPGYT-----GVNCEVDIDNCQ--S 1220
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGG----CHPRATCANTDGS 498
C A CI+ + C C + G + + N C+ C
Sbjct: 1221 HQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTE 1280
Query: 499 FRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
+C+C G+ G+ + DIDECA+DP C NG C + ++C CDV F
Sbjct: 1281 LKCMCRPGFTGE----------WCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAF 1327
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 25/173 (14%)
Query: 390 LQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPA 448
LQ +V P L G G+C + S+ C CP G+S G C + DEC C H
Sbjct: 1138 LQLNVCNSNPCLHG-GNCEDIYSSYHCSCPLGWS-----GKHCELNIDECFSNPC-IH-- 1188
Query: 449 ADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
+C + ++ C C G+ G CE D+D C ++ C ATC + + CLC +
Sbjct: 1189 GNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNF 1244
Query: 508 KGDGYGLRTVCCVYSCVDIDECANDPT--LCEN-GHCSNTPGGYECDCDVGFT 557
G C S + C N+ T C N G+C+ +C C GFT
Sbjct: 1245 TGK-------FCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Score = 52.4 bits (120), Expect = 4e-06
Identities = 46/184 (25%), Positives = 65/184 (35%), Gaps = 25/184 (13%)
Query: 200 CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C+ ++ C N L GG C + S+ C C G L +IDEC S C +G
Sbjct: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWSGKHCEL---NIDEC--FSNPCIHGN 1190
Query: 260 CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
C +++ Y C C+ GY + +C++ Y C C +
Sbjct: 1191 CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGA---TCISHTNGYSCLCFGNF--- 1244
Query: 320 ADGRSCRDI---DECAGGAR---PC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDI 372
G+ CR G + C GG C C C G +DI
Sbjct: 1245 -TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE-----KDI 1298
Query: 373 DECA 376
DECA
Sbjct: 1299 DECA 1302
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 14/85 (16%)
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C ++ C N+ C C + S+ C C G+ G L +IDEC ++
Sbjct: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL----------NIDECFSN 1184
Query: 533 PTLCENGHCSNTPGGYECDCDVGFT 557
P C +G+CS+ Y C C+ G+T
Sbjct: 1185 P--CIHGNCSDRVAAYHCTCEPGYT 1207
>AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 109 bits (261), Expect = 3e-23
Identities = 114/417 (27%), Positives = 169/417 (40%), Gaps = 75/417 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGF--------TCDCFPGYEKDSKNHTC-VDVNECEIVDGVCG 172
C G CG C++ GG C C GY C +D +EC C
Sbjct: 107 CETTIGSCGKNSCQH--GGICHQDPIYPVCICPAGYA----GRFCEIDHDEC--ASSPCQ 158
Query: 173 DGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
+G C + ++C C PGY+ +++DECA +D C+N G + C C H
Sbjct: 159 NGAVCQDGIDGYSCFCVPGYQGRHCD---LEVDECA-SDPCKNEATCLNEIGRYTCICPH 214
Query: 232 GMELAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
++C+ +IDEC S C NGA C++ +G Y C C G+ + +
Sbjct: 215 NYS----GVNCELEIDEC--WSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECAS 268
Query: 290 XXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQCRNT 346
C H CV+ Y C C G C + ++PC C ++
Sbjct: 269 QP-----CLHGGLCVDGENRYSCNCTGSGFT---GTHCETLMPLCW-SKPCHNNATCEDS 319
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
V +YTC C P GA+ C+ D++EC S + + ++ S + Q + G
Sbjct: 320 VDNYTCHCW----PGYTGAQ--CEIDLNECN---SNPCQSNGECVELSSEKQYGRITGLP 370
Query: 406 SC--HNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
S ++ +VC C G++ G C +D +EC C C NLPG++ C C
Sbjct: 371 SSFSYHEASGYVCICQPGFT-----GIHCEEDVNECSSNPCQ--NGGTCENLPGNYTCHC 423
Query: 463 R-DGWRG---DGATCEDV------DECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
D G C D+ +CL NNG C P + F CLC +GY G
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCL-NNGTCIPH--FQDGQHGFSCLCPSGYTG 477
Score = 97.9 bits (233), Expect = 8e-20
Identities = 118/433 (27%), Positives = 165/433 (38%), Gaps = 84/433 (19%)
Query: 172 GDGDCHNTEG--SFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCE 228
G C NT G SF C C PGY IC I C N GG C C
Sbjct: 81 GSATCVNTPGERSFLCKCPPGYS----GTICETTIGSCGKNSCQ-HGGICHQDPIYPVCI 135
Query: 229 CGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXX 287
C G R D DEC+ S C NGA C++ + Y C C GY +
Sbjct: 136 CPAGY---AGRFCEIDHDECA--SSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEV 187
Query: 288 XXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRN 345
+ + +C+N G Y C C + G +C +IDEC ++PC G C++
Sbjct: 188 DECASDPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDEC--WSQPCLNGATCQD 241
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVD-ELQKSVD-------- 395
+G+Y C C G + C+ + DECA + VD E + S +
Sbjct: 242 ALGAYFCDCAPGFLGD------HCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTG 295
Query: 396 ---PQIPELCGAGSCHN------TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
+ LC + CHN ++ ++ C C GY+ G C D +EC C
Sbjct: 296 THCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYT-----GAQCEIDLNECNSNPCQS 350
Query: 446 HPAADCI------------NLPGSFQ--------CRCRDGWRGDGATCEDVDECLTNNGG 485
+ +C+ LP SF C C+ G+ G EDV+EC +N
Sbjct: 351 N--GECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCE-EDVNECSSN--P 405
Query: 486 CHPRATCANTDGSFRCLCD-TGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNT 544
C TC N G++ C C YG R + +C N+ T H +
Sbjct: 406 CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIP--HFQDG 463
Query: 545 PGGYECDCDVGFT 557
G+ C C G+T
Sbjct: 464 QHGFSCLCPSGYT 476
Score = 72.9 bits (171), Expect = 3e-12
Identities = 84/281 (29%), Positives = 119/281 (42%), Gaps = 45/281 (16%)
Query: 297 CQHS--CVNTPGSYHCTCREGWHLRADGRSCRDI-DECAGGARPC-GGGQCRNTVG--SY 350
CQ++ C + C+C + + D + C ++ D C + PC G C NT G S+
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTAN-NLD-KDCDNMKDPCF--SNPCQGSATCVNTPGERSF 94
Query: 351 TCTCTDG----LVPSAAGA--KPTCQDIDEC-ADLISTIIMMSVDELQKSVDPQIPELCG 403
C C G + + G+ K +CQ C D I + + + + E C
Sbjct: 95 LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDE-CA 153
Query: 404 AGSCHNTIGSFVCQCP-DGYS---VKPEQGPACT-DDDECELGTCDCHPAADCINLPGSF 458
+ C N VCQ DGYS V QG C + DEC + C A C+N G +
Sbjct: 154 SSPCQN---GAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--ASDPCKNEATCLNEIGRY 208
Query: 459 QCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C C + G CE ++DEC + C ATC + G++ C C G+ GD L T
Sbjct: 209 TCICPHNY--SGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCELNT- 263
Query: 518 CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDC-DVGFT 557
DECA+ P L G C + Y C+C GFT
Sbjct: 264 ---------DECASQPCL-HGGLCVDGENRYSCNCTGSGFT 294
Score = 72.1 bits (169), Expect = 5e-12
Identities = 98/369 (26%), Positives = 138/369 (37%), Gaps = 76/369 (20%)
Query: 206 CADNDALCRGGRCVN--TAGSFR----CECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C N+ C C N T F C C D+ C ++ + ++ +
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNL-DK-DCDNMKDPCFSNPCQGSAT 84
Query: 260 CENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREG 315
C N G ++ C C GY+ + ++ CQH C P C C G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICET-----TIGSCGKNSCQHGGICHQDPIYPVCICPAG 139
Query: 316 WHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DI 372
+ GR C D DECA PC G C++ + Y+C C VP G C ++
Sbjct: 140 YA----GRFCEIDHDECASS--PCQNGAVCQDGIDGYSCFC----VPGYQGRH--CDLEV 187
Query: 373 DECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC 432
DECA DP E +C N IG + C CP YS G C
Sbjct: 188 DECAS-----------------DPCKNE----ATCLNEIGRYTCICPHNYS-----GVNC 221
Query: 433 T-DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRA 490
+ DEC + C A C + G++ C C G+ GD CE + DEC + C
Sbjct: 222 ELEIDEC--WSQPCLNGATCQDALGAYFCDCAPGFLGDH--CELNTDECASQP--CLHGG 275
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYEC 550
C + + + C C TG G T+ + C + P N C ++ Y C
Sbjct: 276 LCVDGENRYSCNC-TGSGFTGTHCETLMPL--------CWSKPCH-NNATCEDSVDNYTC 325
Query: 551 DCDVGFTRA 559
C G+T A
Sbjct: 326 HCWPGYTGA 334
Score = 72.1 bits (169), Expect = 5e-12
Identities = 60/220 (27%), Positives = 88/220 (40%), Gaps = 43/220 (19%)
Query: 297 CQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCT 353
C H +C + SYHC+C GW G+ C +IDEC + PC G C + V +Y CT
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECF--SNPCIHGNCSDRVAAYHCT 1201
Query: 354 CTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C P G C+ DID C Q + +C +
Sbjct: 1202 CE----PGYTGVN--CEVDIDNC---------------------QSHQCANGATCISHTN 1234
Query: 413 SFVCQCPDGYSVK-PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
+ C C ++ K Q + E C+ +C +C CR G+ G+
Sbjct: 1235 GYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEW- 1293
Query: 472 TCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
CE D+DEC ++ C C + F+CLCD + G+
Sbjct: 1294 -CEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFAGE 1330
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/166 (26%), Positives = 73/166 (43%), Gaps = 17/166 (10%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG- 174
++ ++EC + P C HG C + + + C C PGY + + VD++ C+ C +G
Sbjct: 1175 ELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGY---TGVNCEVDIDNCQ--SHQCANGA 1227
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECAD---NDALCRGGRCVNTAGSFRCECGH 231
C + ++C C + + + C + N GG C +C C
Sbjct: 1228 TCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP 1287
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYA 276
G KDIDEC+ S C NG C++ + +QC+CD +A
Sbjct: 1288 GF---TGEWCEKDIDECA--SDPCVNGGLCQDLLNKFQCLCDVAFA 1328
Score = 63.3 bits (147), Expect = 2e-09
Identities = 61/239 (25%), Positives = 91/239 (38%), Gaps = 55/239 (23%)
Query: 325 CRDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
C ++ C + PC GG C + SY C+C P K +IDEC
Sbjct: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSC-----PLGWSGKHCELNIDECFS------ 1183
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGT 442
+P C G+C + + ++ C C GY+ G C D D C+ +
Sbjct: 1184 -----------NP-----CIHGNCSDRVAAYHCTCEPGYT-----GVNCEVDIDNCQ--S 1220
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGG----CHPRATCANTDGS 498
C A CI+ + C C + G + + N C+ C
Sbjct: 1221 HQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTE 1280
Query: 499 FRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
+C+C G+ G+ + DIDECA+DP C NG C + ++C CDV F
Sbjct: 1281 LKCMCRPGFTGE----------WCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAF 1327
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 25/173 (14%)
Query: 390 LQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPA 448
LQ +V P L G G+C + S+ C CP G+S G C + DEC C H
Sbjct: 1138 LQLNVCNSNPCLHG-GNCEDIYSSYHCSCPLGWS-----GKHCELNIDECFSNPC-IH-- 1188
Query: 449 ADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
+C + ++ C C G+ G CE D+D C ++ C ATC + + CLC +
Sbjct: 1189 GNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNF 1244
Query: 508 KGDGYGLRTVCCVYSCVDIDECANDPT--LCEN-GHCSNTPGGYECDCDVGFT 557
G C S + C N+ T C N G+C+ +C C GFT
Sbjct: 1245 TGK-------FCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Score = 52.4 bits (120), Expect = 4e-06
Identities = 46/184 (25%), Positives = 65/184 (35%), Gaps = 25/184 (13%)
Query: 200 CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C+ ++ C N L GG C + S+ C C G L +IDEC S C +G
Sbjct: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWSGKHCEL---NIDEC--FSNPCIHGN 1190
Query: 260 CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
C +++ Y C C+ GY + +C++ Y C C +
Sbjct: 1191 CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGA---TCISHTNGYSCLCFGNF--- 1244
Query: 320 ADGRSCRDI---DECAGGAR---PC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDI 372
G+ CR G + C GG C C C G +DI
Sbjct: 1245 -TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE-----KDI 1298
Query: 373 DECA 376
DECA
Sbjct: 1299 DECA 1302
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 14/85 (16%)
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C ++ C N+ C C + S+ C C G+ G L +IDEC ++
Sbjct: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL----------NIDECFSN 1184
Query: 533 PTLCENGHCSNTPGGYECDCDVGFT 557
P C +G+CS+ Y C C+ G+T
Sbjct: 1185 P--CIHGNCSDRVAAYHCTCEPGYT 1207
>AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 109 bits (261), Expect = 3e-23
Identities = 114/417 (27%), Positives = 169/417 (40%), Gaps = 75/417 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGF--------TCDCFPGYEKDSKNHTC-VDVNECEIVDGVCG 172
C G CG C++ GG C C GY C +D +EC C
Sbjct: 107 CETTIGSCGKNSCQH--GGICHQDPIYPVCICPAGYA----GRFCEIDHDEC--ASSPCQ 158
Query: 173 DGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
+G C + ++C C PGY+ +++DECA +D C+N G + C C H
Sbjct: 159 NGAVCQDGIDGYSCFCVPGYQGRHCD---LEVDECA-SDPCKNEATCLNEIGRYTCICPH 214
Query: 232 GMELAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
++C+ +IDEC S C NGA C++ +G Y C C G+ + +
Sbjct: 215 NYS----GVNCELEIDEC--WSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECAS 268
Query: 290 XXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQCRNT 346
C H CV+ Y C C G C + ++PC C ++
Sbjct: 269 QP-----CLHGGLCVDGENRYSCNCTGSGFT---GTHCETLMPLCW-SKPCHNNATCEDS 319
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
V +YTC C P GA+ C+ D++EC S + + ++ S + Q + G
Sbjct: 320 VDNYTCHCW----PGYTGAQ--CEIDLNECN---SNPCQSNGECVELSSEKQYGRITGLP 370
Query: 406 SC--HNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
S ++ +VC C G++ G C +D +EC C C NLPG++ C C
Sbjct: 371 SSFSYHEASGYVCICQPGFT-----GIHCEEDVNECSSNPCQ--NGGTCENLPGNYTCHC 423
Query: 463 R-DGWRG---DGATCEDV------DECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
D G C D+ +CL NNG C P + F CLC +GY G
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCL-NNGTCIPH--FQDGQHGFSCLCPSGYTG 477
Score = 97.9 bits (233), Expect = 8e-20
Identities = 118/433 (27%), Positives = 165/433 (38%), Gaps = 84/433 (19%)
Query: 172 GDGDCHNTEG--SFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCE 228
G C NT G SF C C PGY IC I C N GG C C
Sbjct: 81 GSATCVNTPGERSFLCKCPPGYS----GTICETTIGSCGKNSCQ-HGGICHQDPIYPVCI 135
Query: 229 CGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXX 287
C G R D DEC+ S C NGA C++ + Y C C GY +
Sbjct: 136 CPAGY---AGRFCEIDHDECA--SSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEV 187
Query: 288 XXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRN 345
+ + +C+N G Y C C + G +C +IDEC ++PC G C++
Sbjct: 188 DECASDPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDEC--WSQPCLNGATCQD 241
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVD-ELQKSVD-------- 395
+G+Y C C G + C+ + DECA + VD E + S +
Sbjct: 242 ALGAYFCDCAPGFLGD------HCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTG 295
Query: 396 ---PQIPELCGAGSCHN------TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
+ LC + CHN ++ ++ C C GY+ G C D +EC C
Sbjct: 296 THCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYT-----GAQCEIDLNECNSNPCQS 350
Query: 446 HPAADCI------------NLPGSFQ--------CRCRDGWRGDGATCEDVDECLTNNGG 485
+ +C+ LP SF C C+ G+ G EDV+EC +N
Sbjct: 351 N--GECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCE-EDVNECSSN--P 405
Query: 486 CHPRATCANTDGSFRCLCD-TGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNT 544
C TC N G++ C C YG R + +C N+ T H +
Sbjct: 406 CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIP--HFQDG 463
Query: 545 PGGYECDCDVGFT 557
G+ C C G+T
Sbjct: 464 QHGFSCLCPSGYT 476
Score = 72.9 bits (171), Expect = 3e-12
Identities = 84/281 (29%), Positives = 119/281 (42%), Gaps = 45/281 (16%)
Query: 297 CQHS--CVNTPGSYHCTCREGWHLRADGRSCRDI-DECAGGARPC-GGGQCRNTVG--SY 350
CQ++ C + C+C + + D + C ++ D C + PC G C NT G S+
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTAN-NLD-KDCDNMKDPCF--SNPCQGSATCVNTPGERSF 94
Query: 351 TCTCTDG----LVPSAAGA--KPTCQDIDEC-ADLISTIIMMSVDELQKSVDPQIPELCG 403
C C G + + G+ K +CQ C D I + + + + E C
Sbjct: 95 LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDE-CA 153
Query: 404 AGSCHNTIGSFVCQCP-DGYS---VKPEQGPACT-DDDECELGTCDCHPAADCINLPGSF 458
+ C N VCQ DGYS V QG C + DEC + C A C+N G +
Sbjct: 154 SSPCQN---GAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--ASDPCKNEATCLNEIGRY 208
Query: 459 QCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C C + G CE ++DEC + C ATC + G++ C C G+ GD L T
Sbjct: 209 TCICPHNY--SGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCELNT- 263
Query: 518 CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDC-DVGFT 557
DECA+ P L G C + Y C+C GFT
Sbjct: 264 ---------DECASQPCL-HGGLCVDGENRYSCNCTGSGFT 294
Score = 72.1 bits (169), Expect = 5e-12
Identities = 98/369 (26%), Positives = 138/369 (37%), Gaps = 76/369 (20%)
Query: 206 CADNDALCRGGRCVN--TAGSFR----CECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C N+ C C N T F C C D+ C ++ + ++ +
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNL-DK-DCDNMKDPCFSNPCQGSAT 84
Query: 260 CENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREG 315
C N G ++ C C GY+ + ++ CQH C P C C G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICET-----TIGSCGKNSCQHGGICHQDPIYPVCICPAG 139
Query: 316 WHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DI 372
+ GR C D DECA PC G C++ + Y+C C VP G C ++
Sbjct: 140 YA----GRFCEIDHDECASS--PCQNGAVCQDGIDGYSCFC----VPGYQGRH--CDLEV 187
Query: 373 DECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC 432
DECA DP E +C N IG + C CP YS G C
Sbjct: 188 DECAS-----------------DPCKNE----ATCLNEIGRYTCICPHNYS-----GVNC 221
Query: 433 T-DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRA 490
+ DEC + C A C + G++ C C G+ GD CE + DEC + C
Sbjct: 222 ELEIDEC--WSQPCLNGATCQDALGAYFCDCAPGFLGDH--CELNTDECASQP--CLHGG 275
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYEC 550
C + + + C C TG G T+ + C + P N C ++ Y C
Sbjct: 276 LCVDGENRYSCNC-TGSGFTGTHCETLMPL--------CWSKPCH-NNATCEDSVDNYTC 325
Query: 551 DCDVGFTRA 559
C G+T A
Sbjct: 326 HCWPGYTGA 334
Score = 72.1 bits (169), Expect = 5e-12
Identities = 60/220 (27%), Positives = 88/220 (40%), Gaps = 43/220 (19%)
Query: 297 CQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCT 353
C H +C + SYHC+C GW G+ C +IDEC + PC G C + V +Y CT
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECF--SNPCIHGNCSDRVAAYHCT 1201
Query: 354 CTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C P G C+ DID C Q + +C +
Sbjct: 1202 CE----PGYTGVN--CEVDIDNC---------------------QSHQCANGATCISHTN 1234
Query: 413 SFVCQCPDGYSVK-PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
+ C C ++ K Q + E C+ +C +C CR G+ G+
Sbjct: 1235 GYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEW- 1293
Query: 472 TCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
CE D+DEC ++ C C + F+CLCD + G+
Sbjct: 1294 -CEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFAGE 1330
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/166 (26%), Positives = 73/166 (43%), Gaps = 17/166 (10%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG- 174
++ ++EC + P C HG C + + + C C PGY + + VD++ C+ C +G
Sbjct: 1175 ELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGY---TGVNCEVDIDNCQ--SHQCANGA 1227
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECAD---NDALCRGGRCVNTAGSFRCECGH 231
C + ++C C + + + C + N GG C +C C
Sbjct: 1228 TCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP 1287
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYA 276
G KDIDEC+ S C NG C++ + +QC+CD +A
Sbjct: 1288 GF---TGEWCEKDIDECA--SDPCVNGGLCQDLLNKFQCLCDVAFA 1328
Score = 63.3 bits (147), Expect = 2e-09
Identities = 61/239 (25%), Positives = 91/239 (38%), Gaps = 55/239 (23%)
Query: 325 CRDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
C ++ C + PC GG C + SY C+C P K +IDEC
Sbjct: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSC-----PLGWSGKHCELNIDECFS------ 1183
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGT 442
+P C G+C + + ++ C C GY+ G C D D C+ +
Sbjct: 1184 -----------NP-----CIHGNCSDRVAAYHCTCEPGYT-----GVNCEVDIDNCQ--S 1220
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGG----CHPRATCANTDGS 498
C A CI+ + C C + G + + N C+ C
Sbjct: 1221 HQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTE 1280
Query: 499 FRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
+C+C G+ G+ + DIDECA+DP C NG C + ++C CDV F
Sbjct: 1281 LKCMCRPGFTGE----------WCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAF 1327
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 25/173 (14%)
Query: 390 LQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPA 448
LQ +V P L G G+C + S+ C CP G+S G C + DEC C H
Sbjct: 1138 LQLNVCNSNPCLHG-GNCEDIYSSYHCSCPLGWS-----GKHCELNIDECFSNPC-IH-- 1188
Query: 449 ADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
+C + ++ C C G+ G CE D+D C ++ C ATC + + CLC +
Sbjct: 1189 GNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNF 1244
Query: 508 KGDGYGLRTVCCVYSCVDIDECANDPT--LCEN-GHCSNTPGGYECDCDVGFT 557
G C S + C N+ T C N G+C+ +C C GFT
Sbjct: 1245 TGK-------FCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Score = 52.4 bits (120), Expect = 4e-06
Identities = 46/184 (25%), Positives = 65/184 (35%), Gaps = 25/184 (13%)
Query: 200 CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C+ ++ C N L GG C + S+ C C G L +IDEC S C +G
Sbjct: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWSGKHCEL---NIDEC--FSNPCIHGN 1190
Query: 260 CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
C +++ Y C C+ GY + +C++ Y C C +
Sbjct: 1191 CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGA---TCISHTNGYSCLCFGNF--- 1244
Query: 320 ADGRSCRDI---DECAGGAR---PC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDI 372
G+ CR G + C GG C C C G +DI
Sbjct: 1245 -TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE-----KDI 1298
Query: 373 DECA 376
DECA
Sbjct: 1299 DECA 1302
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 14/85 (16%)
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C ++ C N+ C C + S+ C C G+ G L +IDEC ++
Sbjct: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL----------NIDECFSN 1184
Query: 533 PTLCENGHCSNTPGGYECDCDVGFT 557
P C +G+CS+ Y C C+ G+T
Sbjct: 1185 P--CIHGNCSDRVAAYHCTCEPGYT 1207
>AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.
Length = 1376
Score = 109 bits (261), Expect = 3e-23
Identities = 114/417 (27%), Positives = 169/417 (40%), Gaps = 75/417 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGF--------TCDCFPGYEKDSKNHTC-VDVNECEIVDGVCG 172
C G CG C++ GG C C GY C +D +EC C
Sbjct: 107 CETTIGSCGKNSCQH--GGICHQDPIYPVCICPAGYA----GRFCEIDHDEC--ASSPCQ 158
Query: 173 DGD-CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGH 231
+G C + ++C C PGY+ +++DECA +D C+N G + C C H
Sbjct: 159 NGAVCQDGIDGYSCFCVPGYQGRHCD---LEVDECA-SDPCKNEATCLNEIGRYTCICPH 214
Query: 232 GMELAPDRLSCK-DIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXX 289
++C+ +IDEC S C NGA C++ +G Y C C G+ + +
Sbjct: 215 NYS----GVNCELEIDEC--WSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECAS 268
Query: 290 XXXXXXRCQHS--CVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPC-GGGQCRNT 346
C H CV+ Y C C G C + ++PC C ++
Sbjct: 269 QP-----CLHGGLCVDGENRYSCNCTGSGFT---GTHCETLMPLCW-SKPCHNNATCEDS 319
Query: 347 VGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAG 405
V +YTC C P GA+ C+ D++EC S + + ++ S + Q + G
Sbjct: 320 VDNYTCHCW----PGYTGAQ--CEIDLNECN---SNPCQSNGECVELSSEKQYGRITGLP 370
Query: 406 SC--HNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
S ++ +VC C G++ G C +D +EC C C NLPG++ C C
Sbjct: 371 SSFSYHEASGYVCICQPGFT-----GIHCEEDVNECSSNPCQ--NGGTCENLPGNYTCHC 423
Query: 463 R-DGWRG---DGATCEDV------DECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
D G C D+ +CL NNG C P + F CLC +GY G
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCL-NNGTCIPH--FQDGQHGFSCLCPSGYTG 477
Score = 97.9 bits (233), Expect = 8e-20
Identities = 118/433 (27%), Positives = 165/433 (38%), Gaps = 84/433 (19%)
Query: 172 GDGDCHNTEG--SFTCHCRPGYKADDFSKIC-VDIDECADNDALCRGGRCVNTAGSFRCE 228
G C NT G SF C C PGY IC I C N GG C C
Sbjct: 81 GSATCVNTPGERSFLCKCPPGYS----GTICETTIGSCGKNSCQ-HGGICHQDPIYPVCI 135
Query: 229 CGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXX 287
C G R D DEC+ S C NGA C++ + Y C C GY +
Sbjct: 136 CPAGY---AGRFCEIDHDECA--SSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEV 187
Query: 288 XXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRN 345
+ + +C+N G Y C C + G +C +IDEC ++PC G C++
Sbjct: 188 DECASDPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDEC--WSQPCLNGATCQD 241
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVD-ELQKSVD-------- 395
+G+Y C C G + C+ + DECA + VD E + S +
Sbjct: 242 ALGAYFCDCAPGFLGD------HCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTG 295
Query: 396 ---PQIPELCGAGSCHN------TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDC 445
+ LC + CHN ++ ++ C C GY+ G C D +EC C
Sbjct: 296 THCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYT-----GAQCEIDLNECNSNPCQS 350
Query: 446 HPAADCI------------NLPGSFQ--------CRCRDGWRGDGATCEDVDECLTNNGG 485
+ +C+ LP SF C C+ G+ G EDV+EC +N
Sbjct: 351 N--GECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCE-EDVNECSSN--P 405
Query: 486 CHPRATCANTDGSFRCLCD-TGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNT 544
C TC N G++ C C YG R + +C N+ T H +
Sbjct: 406 CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIP--HFQDG 463
Query: 545 PGGYECDCDVGFT 557
G+ C C G+T
Sbjct: 464 QHGFSCLCPSGYT 476
Score = 72.9 bits (171), Expect = 3e-12
Identities = 84/281 (29%), Positives = 119/281 (42%), Gaps = 45/281 (16%)
Query: 297 CQHS--CVNTPGSYHCTCREGWHLRADGRSCRDI-DECAGGARPC-GGGQCRNTVG--SY 350
CQ++ C + C+C + + D + C ++ D C + PC G C NT G S+
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTAN-NLD-KDCDNMKDPCF--SNPCQGSATCVNTPGERSF 94
Query: 351 TCTCTDG----LVPSAAGA--KPTCQDIDEC-ADLISTIIMMSVDELQKSVDPQIPELCG 403
C C G + + G+ K +CQ C D I + + + + E C
Sbjct: 95 LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDE-CA 153
Query: 404 AGSCHNTIGSFVCQCP-DGYS---VKPEQGPACT-DDDECELGTCDCHPAADCINLPGSF 458
+ C N VCQ DGYS V QG C + DEC + C A C+N G +
Sbjct: 154 SSPCQN---GAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--ASDPCKNEATCLNEIGRY 208
Query: 459 QCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTV 517
C C + G CE ++DEC + C ATC + G++ C C G+ GD L T
Sbjct: 209 TCICPHNY--SGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCELNT- 263
Query: 518 CCVYSCVDIDECANDPTLCENGHCSNTPGGYECDC-DVGFT 557
DECA+ P L G C + Y C+C GFT
Sbjct: 264 ---------DECASQPCL-HGGLCVDGENRYSCNCTGSGFT 294
Score = 72.1 bits (169), Expect = 5e-12
Identities = 98/369 (26%), Positives = 138/369 (37%), Gaps = 76/369 (20%)
Query: 206 CADNDALCRGGRCVN--TAGSFR----CECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C N+ C C N T F C C D+ C ++ + ++ +
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNL-DK-DCDNMKDPCFSNPCQGSAT 84
Query: 260 CENQMG--TYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS--CVNTPGSYHCTCREG 315
C N G ++ C C GY+ + ++ CQH C P C C G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICET-----TIGSCGKNSCQHGGICHQDPIYPVCICPAG 139
Query: 316 WHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQ-DI 372
+ GR C D DECA PC G C++ + Y+C C VP G C ++
Sbjct: 140 YA----GRFCEIDHDECASS--PCQNGAVCQDGIDGYSCFC----VPGYQGRH--CDLEV 187
Query: 373 DECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC 432
DECA DP E +C N IG + C CP YS G C
Sbjct: 188 DECAS-----------------DPCKNE----ATCLNEIGRYTCICPHNYS-----GVNC 221
Query: 433 T-DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRA 490
+ DEC + C A C + G++ C C G+ GD CE + DEC + C
Sbjct: 222 ELEIDEC--WSQPCLNGATCQDALGAYFCDCAPGFLGDH--CELNTDECASQP--CLHGG 275
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYEC 550
C + + + C C TG G T+ + C + P N C ++ Y C
Sbjct: 276 LCVDGENRYSCNC-TGSGFTGTHCETLMPL--------CWSKPCH-NNATCEDSVDNYTC 325
Query: 551 DCDVGFTRA 559
C G+T A
Sbjct: 326 HCWPGYTGA 334
Score = 72.1 bits (169), Expect = 5e-12
Identities = 60/220 (27%), Positives = 88/220 (40%), Gaps = 43/220 (19%)
Query: 297 CQH--SCVNTPGSYHCTCREGWHLRADGRSCR-DIDECAGGARPCGGGQCRNTVGSYTCT 353
C H +C + SYHC+C GW G+ C +IDEC + PC G C + V +Y CT
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECF--SNPCIHGNCSDRVAAYHCT 1201
Query: 354 CTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIG 412
C P G C+ DID C Q + +C +
Sbjct: 1202 CE----PGYTGVN--CEVDIDNC---------------------QSHQCANGATCISHTN 1234
Query: 413 SFVCQCPDGYSVK-PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGA 471
+ C C ++ K Q + E C+ +C +C CR G+ G+
Sbjct: 1235 GYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEW- 1293
Query: 472 TCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
CE D+DEC ++ C C + F+CLCD + G+
Sbjct: 1294 -CEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFAGE 1330
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/166 (26%), Positives = 73/166 (43%), Gaps = 17/166 (10%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG- 174
++ ++EC + P C HG C + + + C C PGY + + VD++ C+ C +G
Sbjct: 1175 ELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGY---TGVNCEVDIDNCQ--SHQCANGA 1227
Query: 175 DCHNTEGSFTCHCRPGYKADDFSKICVDIDECAD---NDALCRGGRCVNTAGSFRCECGH 231
C + ++C C + + + C + N GG C +C C
Sbjct: 1228 TCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP 1287
Query: 232 GMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGYA 276
G KDIDEC+ S C NG C++ + +QC+CD +A
Sbjct: 1288 GF---TGEWCEKDIDECA--SDPCVNGGLCQDLLNKFQCLCDVAFA 1328
Score = 63.3 bits (147), Expect = 2e-09
Identities = 61/239 (25%), Positives = 91/239 (38%), Gaps = 55/239 (23%)
Query: 325 CRDIDECAGGARPC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
C ++ C + PC GG C + SY C+C P K +IDEC
Sbjct: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSC-----PLGWSGKHCELNIDECFS------ 1183
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGT 442
+P C G+C + + ++ C C GY+ G C D D C+ +
Sbjct: 1184 -----------NP-----CIHGNCSDRVAAYHCTCEPGYT-----GVNCEVDIDNCQ--S 1220
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGG----CHPRATCANTDGS 498
C A CI+ + C C + G + + N C+ C
Sbjct: 1221 HQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTE 1280
Query: 499 FRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGF 556
+C+C G+ G+ + DIDECA+DP C NG C + ++C CDV F
Sbjct: 1281 LKCMCRPGFTGE----------WCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAF 1327
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 25/173 (14%)
Query: 390 LQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPA 448
LQ +V P L G G+C + S+ C CP G+S G C + DEC C H
Sbjct: 1138 LQLNVCNSNPCLHG-GNCEDIYSSYHCSCPLGWS-----GKHCELNIDECFSNPC-IH-- 1188
Query: 449 ADCINLPGSFQCRCRDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
+C + ++ C C G+ G CE D+D C ++ C ATC + + CLC +
Sbjct: 1189 GNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNF 1244
Query: 508 KGDGYGLRTVCCVYSCVDIDECANDPT--LCEN-GHCSNTPGGYECDCDVGFT 557
G C S + C N+ T C N G+C+ +C C GFT
Sbjct: 1245 TGK-------FCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Score = 52.4 bits (120), Expect = 4e-06
Identities = 46/184 (25%), Positives = 65/184 (35%), Gaps = 25/184 (13%)
Query: 200 CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA 259
C+ ++ C N L GG C + S+ C C G L +IDEC S C +G
Sbjct: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWSGKHCEL---NIDEC--FSNPCIHGN 1190
Query: 260 CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLR 319
C +++ Y C C+ GY + +C++ Y C C +
Sbjct: 1191 CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGA---TCISHTNGYSCLCFGNF--- 1244
Query: 320 ADGRSCRDI---DECAGGAR---PC-GGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDI 372
G+ CR G + C GG C C C G +DI
Sbjct: 1245 -TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE-----KDI 1298
Query: 373 DECA 376
DECA
Sbjct: 1299 DECA 1302
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 14/85 (16%)
Query: 473 CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECAND 532
C ++ C N+ C C + S+ C C G+ G L +IDEC ++
Sbjct: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL----------NIDECFSN 1184
Query: 533 PTLCENGHCSNTPGGYECDCDVGFT 557
P C +G+CS+ Y C C+ G+T
Sbjct: 1185 P--CIHGNCSDRVAAYHCTCEPGYT 1207
>AL021578-1|CAB46380.1| 622|Homo sapiens matrilin 4 protein.
Length = 622
Score = 108 bits (260), Expect = 4e-23
Identities = 77/228 (33%), Positives = 104/228 (45%), Gaps = 13/228 (5%)
Query: 197 SKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICS 256
S++C D+CA+ C+ +CVN F C C G +LA D SC ID C+ + C
Sbjct: 211 SRLCGK-DQCAEGGHGCQH-QCVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCE 268
Query: 257 NGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGW 316
+ C N G+Y C C G+ + CQH CV+TPG C CREG
Sbjct: 269 HH-CVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGH 327
Query: 317 HLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECA 376
L+ DGRSC+ D C G C QC + SY C C +G A G + + C
Sbjct: 328 DLQPDGRSCQVRDLCNGVDHGC-EFQCVSEGLSYRCLCPEGRQLQADG-----KSCNRCR 381
Query: 377 DLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSV 424
+ ++++ VD KSV PQ EL N I F+ P+G V
Sbjct: 382 EGHVDLVLL-VDG-SKSVRPQNFEL--VKRFVNQIVDFLDVSPEGTRV 425
Score = 100 bits (240), Expect = 1e-20
Identities = 54/150 (36%), Positives = 70/150 (46%), Gaps = 2/150 (1%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N F C C PGYK +K C+ ID CA+ C CVN+ GS+ C C G L
Sbjct: 230 CVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCE-HHCVNSPGSYFCHCQVGFVL 288
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D+ SC+ ID CS + C + C + G +C C EG+
Sbjct: 289 QQDQRSCRAIDYCSFGNHSCQH-ECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDH 347
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
C+ CV+ SY C C EG L+ADG+SC
Sbjct: 348 GCEFQCVSEGLSYRCLCPEGRQLQADGKSC 377
Score = 96.3 bits (229), Expect = 3e-19
Identities = 52/156 (33%), Positives = 80/156 (51%), Gaps = 6/156 (3%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGDCHN 178
++CA C H +C N F C C PGY+ + N +C+ ++ C +G G + C N
Sbjct: 217 DQCAEGGHGCQH-QCVNAWAMFHCTCNPGYKLAADNKSCLAIDLC--AEGTHGCEHHCVN 273
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
+ GS+ CHC+ G+ + C ID C+ + C+ CV+T G RC C G +L PD
Sbjct: 274 SPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQ-HECVSTPGGPRCHCREGHDLQPD 332
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
SC+ D C+ C C ++ +Y+C+C EG
Sbjct: 333 GRSCQVRDLCNGVDHGC-EFQCVSEGLSYRCLCPEG 367
Score = 71.7 bits (168), Expect = 6e-12
Identities = 51/161 (31%), Positives = 65/161 (40%), Gaps = 15/161 (9%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N F C C GY + + +C D C GT C C+N PGS+ C C+ G+
Sbjct: 230 CVNAWAMFHCTCNPGYKLAADN-KSCLAIDLCAEGTHGCEH--HCVNSPGSYFCHCQVGF 286
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ D +C +D C N C C +T G RC C G+ G SC
Sbjct: 287 VLQQDQRSCRAIDYCSFGNHSCQHE--CVSTPGGPRCHCREGHDLQPDGR-------SCQ 337
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
D C CE C + Y C C G ADG+SC
Sbjct: 338 VRDLCNGVDHGCEF-QCVSEGLSYRCLCPEGRQLQADGKSC 377
Score = 69.7 bits (163), Expect = 3e-11
Identities = 60/211 (28%), Positives = 85/211 (40%), Gaps = 32/211 (15%)
Query: 318 LRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECAD 377
L+ R C D+CA G C QC N + CTC G A +C ID CA
Sbjct: 207 LQFQSRLCGK-DQCAEGGHGCQH-QCVNAWAMFHCTCNPGY--KLAADNKSCLAIDLCA- 261
Query: 378 LISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE 437
+ C C N+ GS+ C C G+ ++ +Q +C D
Sbjct: 262 -------------------EGTHGC-EHHCVNSPGSYFCHCQVGFVLQQDQ-RSCRAIDY 300
Query: 438 CELGTCDCHPAADCINLPGSFQCRCRDG--WRGDGATCEDVDECLTNNGGCHPRATCANT 495
C G C +C++ PG +C CR+G + DG +C+ D C + GC C +
Sbjct: 301 CSFGNHSCQ--HECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGC--EFQCVSE 356
Query: 496 DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDI 526
S+RCLC G + G C VD+
Sbjct: 357 GLSYRCLCPEGRQLQADGKSCNRCREGHVDL 387
Score = 68.5 bits (160), Expect = 6e-11
Identities = 43/132 (32%), Positives = 56/132 (42%), Gaps = 14/132 (10%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCA 493
D+C G C C+N F C C G++ D +C +D C GC C
Sbjct: 217 DQCAEGGHGCQH--QCVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHH--CV 272
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD 553
N+ GS+ C C G+ R SC ID C+ C++ C +TPGG C C
Sbjct: 273 NSPGSYFCHCQVGFVLQ-QDQR------SCRAIDYCSFGNHSCQH-ECVSTPGGPRCHCR 324
Query: 554 VGFTRAADGRSC 565
G DGRSC
Sbjct: 325 EGHDLQPDGRSC 336
Score = 35.1 bits (77), Expect = 0.67
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 527 DECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
D+CA C++ C N + C C+ G+ AAD +SCL
Sbjct: 217 DQCAEGGHGCQH-QCVNAWAMFHCTCNPGYKLAADNKSCL 255
>AL021578-2|CAI21077.1| 432|Homo sapiens matrilin 4 protein.
Length = 432
Score = 107 bits (258), Expect = 8e-23
Identities = 75/221 (33%), Positives = 100/221 (45%), Gaps = 12/221 (5%)
Query: 204 DECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACENQ 263
D+CA+ C+ +CVN F C C G +LA D SC ID C+ + C + C N
Sbjct: 27 DQCAEGGHGCQH-QCVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHH-CVNS 84
Query: 264 MGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGR 323
G+Y C C G+ + CQH CV+TPG C CREG L+ DGR
Sbjct: 85 PGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGR 144
Query: 324 SCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
SC+ D C G C QC + SY C C +G A G + + C + ++
Sbjct: 145 SCQVRDLCNGVDHGC-EFQCVSEGLSYRCLCPEGRQLQADG-----KSCNRCREGHVDLV 198
Query: 384 MMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSV 424
++ VD KSV PQ EL N I F+ P+G V
Sbjct: 199 LL-VDG-SKSVRPQNFEL--VKRFVNQIVDFLDVSPEGTRV 235
Score = 100 bits (240), Expect = 1e-20
Identities = 54/150 (36%), Positives = 70/150 (46%), Gaps = 2/150 (1%)
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMEL 235
C N F C C PGYK +K C+ ID CA+ C CVN+ GS+ C C G L
Sbjct: 40 CVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCE-HHCVNSPGSYFCHCQVGFVL 98
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXX 295
D+ SC+ ID CS + C + C + G +C C EG+
Sbjct: 99 QQDQRSCRAIDYCSFGNHSCQH-ECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDH 157
Query: 296 RCQHSCVNTPGSYHCTCREGWHLRADGRSC 325
C+ CV+ SY C C EG L+ADG+SC
Sbjct: 158 GCEFQCVSEGLSYRCLCPEGRQLQADGKSC 187
Score = 96.3 bits (229), Expect = 3e-19
Identities = 52/156 (33%), Positives = 80/156 (51%), Gaps = 6/156 (3%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGDCHN 178
++CA C H +C N F C C PGY+ + N +C+ ++ C +G G + C N
Sbjct: 27 DQCAEGGHGCQH-QCVNAWAMFHCTCNPGYKLAADNKSCLAIDLC--AEGTHGCEHHCVN 83
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
+ GS+ CHC+ G+ + C ID C+ + C+ CV+T G RC C G +L PD
Sbjct: 84 SPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQ-HECVSTPGGPRCHCREGHDLQPD 142
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
SC+ D C+ C C ++ +Y+C+C EG
Sbjct: 143 GRSCQVRDLCNGVDHGC-EFQCVSEGLSYRCLCPEG 177
Score = 71.7 bits (168), Expect = 6e-12
Identities = 51/161 (31%), Positives = 65/161 (40%), Gaps = 15/161 (9%)
Query: 407 CHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGW 466
C N F C C GY + + +C D C GT C C+N PGS+ C C+ G+
Sbjct: 40 CVNAWAMFHCTCNPGYKLAADN-KSCLAIDLCAEGTHGCEH--HCVNSPGSYFCHCQVGF 96
Query: 467 --RGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ D +C +D C N C C +T G RC C G+ G SC
Sbjct: 97 VLQQDQRSCRAIDYCSFGNHSCQHE--CVSTPGGPRCHCREGHDLQPDGR-------SCQ 147
Query: 525 DIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
D C CE C + Y C C G ADG+SC
Sbjct: 148 VRDLCNGVDHGCEF-QCVSEGLSYRCLCPEGRQLQADGKSC 187
Score = 69.7 bits (163), Expect = 3e-11
Identities = 44/135 (32%), Positives = 57/135 (42%), Gaps = 14/135 (10%)
Query: 433 TDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRA 490
T D+C G C C+N F C C G++ D +C +D C GC
Sbjct: 24 TGKDQCAEGGHGCQH--QCVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHH- 80
Query: 491 TCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYEC 550
C N+ GS+ C C G+ R SC ID C+ C++ C +TPGG C
Sbjct: 81 -CVNSPGSYFCHCQVGFVLQ-QDQR------SCRAIDYCSFGNHSCQH-ECVSTPGGPRC 131
Query: 551 DCDVGFTRAADGRSC 565
C G DGRSC
Sbjct: 132 HCREGHDLQPDGRSC 146
Score = 69.3 bits (162), Expect = 3e-11
Identities = 57/200 (28%), Positives = 81/200 (40%), Gaps = 31/200 (15%)
Query: 329 DECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVD 388
D+CA G C QC N + CTC G A +C ID CA
Sbjct: 27 DQCAEGGHGCQH-QCVNAWAMFHCTCNPGY--KLAADNKSCLAIDLCA------------ 71
Query: 389 ELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPA 448
+ C C N+ GS+ C C G+ ++ +Q +C D C G C
Sbjct: 72 --------EGTHGC-EHHCVNSPGSYFCHCQVGFVLQQDQ-RSCRAIDYCSFGNHSCQ-- 119
Query: 449 ADCINLPGSFQCRCRDG--WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTG 506
+C++ PG +C CR+G + DG +C+ D C + GC C + S+RCLC G
Sbjct: 120 HECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGC--EFQCVSEGLSYRCLCPEG 177
Query: 507 YKGDGYGLRTVCCVYSCVDI 526
+ G C VD+
Sbjct: 178 RQLQADGKSCNRCREGHVDL 197
Score = 35.1 bits (77), Expect = 0.67
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 527 DECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
D+CA C++ C N + C C+ G+ AAD +SCL
Sbjct: 27 DQCAEGGHGCQH-QCVNAWAMFHCTCNPGYKLAADNKSCL 65
>AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive
sequence DNA binding protein-1 protein.
Length = 1008
Score = 105 bits (252), Expect = 4e-22
Identities = 134/513 (26%), Positives = 194/513 (37%), Gaps = 112/513 (21%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDC---FPGYEKDSKNH---------------TC 158
M+V++C+ P L G G C +L+G +TC C F G ++ +H TC
Sbjct: 1 MDVDDCSPDPCLNG-GSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 59
Query: 159 VDVNE---CEIVDGVCG---------DGDCHNTE---GSFT--CHCRPGYKADDFSKIC- 200
VD ++ CE +G G D +C N G+ T C C G+ F +C
Sbjct: 60 VDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGF----FGLLCE 115
Query: 201 --VDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNG 258
+ C N GG C+ GS+ C C + S + D C + G
Sbjct: 116 FEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCNSDPCF------NGG 169
Query: 259 ACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SCVNTPGSYHCTCREGW 316
+C+ +Y C C G+ H C++ +C G YHC+C
Sbjct: 170 SCDAHDDSYTCECPRGFHGK----HCEKARPHLCSSGPCRNGGTCKEAGGEYHCSC---- 221
Query: 317 HLRADGRSCR--DIDECAGGARPC-GGGQCRNTVGSYTCTCTDG-------LVPSAAGAK 366
R GR C D CA G PC GG C + +G Y C C G + PS
Sbjct: 222 PYRFTGRHCEIGKPDSCASG--PCHNGGTCFHYIGKYKCDCPPGFSGRYCEIAPSPCFRS 279
Query: 367 P-----TCQDID-----EC-ADLISTIIMMSVD-----ELQKSVDPQIPELCGAGSCHNT 410
P TC+D D C A + VD E++ + GA + +
Sbjct: 280 PCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAAALYAC 339
Query: 411 IGSFVCQCPDGYSVKPEQG-----PACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
+ P V G P C + DEC C H C + + C C G
Sbjct: 340 DRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPC-LH-GGSCQDRVAGYLCLCSTG 397
Query: 466 WRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCV 524
+ +GA CE + DEC + C +C N G++ C C G+ G V+
Sbjct: 398 Y--EGAHCELERDECRAH--PCRNGGSCRNLPGAYVCRCPAGFVG----------VHCET 443
Query: 525 DIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
++D C + P C++ G C + G Y C C GF
Sbjct: 444 EVDACDSSP--CQHGGRCESGGGAYLCVCPEGF 474
Score = 101 bits (242), Expect = 7e-21
Identities = 110/436 (25%), Positives = 166/436 (38%), Gaps = 65/436 (14%)
Query: 132 GRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGY 191
G C G + C C + + +H+ + C D G C + S+TC C G+
Sbjct: 133 GYCMEHGGSYLCVCHTDH---NASHSLP--SPCNS-DPCFNGGSCDAHDDSYTCECPRGF 186
Query: 192 KADDFSKICVDIDECADNDALCR-GGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSI 250
K + C+ CR GG C G + C C + D C+
Sbjct: 187 HGKHCEKARPHL--CSSGP--CRNGGTCKEAGGEYHCSCPY--RFTGRHCEIGKPDSCA- 239
Query: 251 TSGICSNGA-CENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH--SCVNTPGS 307
SG C NG C + +G Y+C C G++ C + +C +
Sbjct: 240 -SGPCHNGGTCFHYIGKYKCDCPPGFS-----GRYCEIAPSPCFRSPCVNGGTCEDRDTD 293
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQCR---NTVGSYTC-TCTDGLVPSAA 363
+ C C+ G+ GR C+ +C G R +G+ C G SA
Sbjct: 294 FFCHCQAGYM----GRRCQAEVDC-GPPEEVKHATLRFNGTRLGAAALYACDRGYSLSAP 348
Query: 364 GAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQCPDGYS 423
CQ ++ + +DE + P L G GSC + + ++C C GY
Sbjct: 349 SRIRVCQPHGVWSEPPQCL---EIDECRSQ-----PCLHG-GSCQDRVAGYLCLCSTGY- 398
Query: 424 VKPEQGPACT-DDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCE-DVDECLT 481
+G C + DEC C C NLPG++ CRC G+ G CE +VD C
Sbjct: 399 ----EGAHCELERDECRAHPC--RNGGSCRNLPGAYVCRCPAGF--VGVHCETEVDAC-- 448
Query: 482 NNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHC 541
++ C C + G++ C+C G+ GY TV D C + P G+C
Sbjct: 449 DSSPCQHGGRCESGGGAYLCVCPEGF--FGYHCETVS--------DPCFSSP-CGGRGYC 497
Query: 542 SNTPGGYECDCDVGFT 557
+ G + C C VG+T
Sbjct: 498 LASNGSHSCTCKVGYT 513
Score = 88.2 bits (209), Expect = 7e-17
Identities = 101/408 (24%), Positives = 149/408 (36%), Gaps = 71/408 (17%)
Query: 122 CAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTE 180
C + P G G C +TC+C G+ H C G C +G C
Sbjct: 160 CNSDPCFNG-GSCDAHDDSYTCECPRGFHG---KH-CEKARPHLCSSGPCRNGGTCKEAG 214
Query: 181 GSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRL 240
G + C C Y+ D CA GG C + G ++C+C G
Sbjct: 215 GEYHCSCP--YRFTGRHCEIGKPDSCASGPCH-NGGTCFHYIGKYKCDCPPGFS----GR 267
Query: 241 SCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHS 300
C+ S + G CE++ + C C GY ++ + +
Sbjct: 268 YCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFN 327
Query: 301 CVNTPGSYHCTCREGWHLRADGR--------------SCRDIDECAGGARPC-GGGQCRN 345
+ C G+ L A R C +IDEC ++PC GG C++
Sbjct: 328 GTRLGAAALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECR--SQPCLHGGSCQD 385
Query: 346 TVGSYTCTCTDGLVPSAAGAKPTCQ-DIDECADLISTIIMMSVDELQKSVDPQIPELCGA 404
V Y C C+ G GA C+ + DEC +
Sbjct: 386 RVAGYLCLCSTGY----EGAH--CELERDEC---------------------RAHPCRNG 418
Query: 405 GSCHNTIGSFVCQCPDGYSVKPEQGPAC-TDDDECELGTCDCHPAADCINLPGSFQCRCR 463
GSC N G++VC+CP G+ G C T+ D C+ + C C + G++ C C
Sbjct: 419 GSCRNLPGAYVCRCPAGF-----VGVHCETEVDACD--SSPCQHGGRCESGGGAYLCVCP 471
Query: 464 DGWRGDGATCEDV-DECLTNNGGCHPRATCANTDGSFRCLCDTGYKGD 510
+G+ G CE V D C ++ C R C ++GS C C GY G+
Sbjct: 472 EGF--FGYHCETVSDPCFSS--PCGGRGYCLASNGSHSCTCKVGYTGE 515
Score = 82.2 bits (194), Expect = 4e-15
Identities = 103/427 (24%), Positives = 146/427 (34%), Gaps = 52/427 (12%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRC 218
+DV++C D G C + G++TC C +K + + + GG C
Sbjct: 1 MDVDDCS-PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 59
Query: 219 VNTAGSFRCECGHGMELAPDRLSCKDI--DECSITSGICSNGACENQMGTYQCVCDEGYA 276
V+ + CEC G L C++ D+C C NG T C C G+
Sbjct: 60 VDADQGYVCECPEGFM----GLDCRERVPDDCE-----CRNGGRCLGANTTLCQCPLGFF 110
Query: 277 QSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGAR 336
+ C+ GSY C C + S + D C G
Sbjct: 111 GLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCNSDPCFNG-- 168
Query: 337 PCGGGQCRNTVGSYTCTCTDGLVPS-AAGAKP------TCQDIDECADLISTIIMMSVDE 389
G C SYTC C G A+P C++ C +
Sbjct: 169 ----GSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYR 224
Query: 390 LQ-KSVDPQIPELCGAGSCHNT------IGSFVCQCPDGYSVKP-EQGPACTDDDECELG 441
+ + P+ C +G CHN IG + C CP G+S + E P+ C G
Sbjct: 225 FTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRYCEIAPSPCFRSPCVNG 284
Query: 442 TCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRC 501
C + F C C+ G+ G C+ +C H T
Sbjct: 285 -------GTCEDRDTDFFCHCQAGYMG--RRCQAEVDCGPPEEVKHATLRFNGTRLGAAA 335
Query: 502 L--CDTGYKGDGYGLRTVCC---VYS----CVDIDECANDPTLCENGHCSNTPGGYECDC 552
L CD GY VC V+S C++IDEC + P L G C + GY C C
Sbjct: 336 LYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCL-HGGSCQDRVAGYLCLC 394
Query: 553 DVGFTRA 559
G+ A
Sbjct: 395 STGYEGA 401
Score = 77.4 bits (182), Expect = 1e-13
Identities = 74/281 (26%), Positives = 105/281 (37%), Gaps = 42/281 (14%)
Query: 300 SCVNTPGSYHCTCREGWH-LRADGRSCRDIDECAGGARPC-GGGQCRNTVGSYTCTCTDG 357
SCV+ G+Y C C E + LR + D C PC GG C + Y C C +G
Sbjct: 16 SCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSA--PCHNGGTCVDADQGYVCECPEG 73
Query: 358 LVPSAAGAKPT----CQDIDECADLISTIIMMSVD------ELQKSVDP-QIPELC-GAG 405
+ + C++ C +T+ + E + + P + C G
Sbjct: 74 FMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGG 133
Query: 406 SCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
C GS++C C ++ C D G+CD H S+ C C G
Sbjct: 134 YCMEHGGSYLCVCHTDHNASHSLPSPCNSDPCFNGGSCDAHD--------DSYTCECPRG 185
Query: 466 WRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVD 525
+ G CE L ++G C TC G + C C + G C
Sbjct: 186 FHGKH--CEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRH-------CEIG--K 234
Query: 526 IDECANDPTLCEN-GHCSNTPGGYECDCDVGFTRAADGRSC 565
D CA+ P C N G C + G Y+CDC GF+ GR C
Sbjct: 235 PDSCASGP--CHNGGTCFHYIGKYKCDCPPGFS----GRYC 269
Score = 73.7 bits (173), Expect = 2e-12
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 13/159 (8%)
Query: 117 MEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
+E++EC + P L G G C++ + G+ C C GYE H ++ +EC G G C
Sbjct: 367 LEIDECRSQPCLHG-GSCQDRVAGYLCLCSTGYEGA---HCELERDECRAHPCRNG-GSC 421
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELA 236
N G++ C C G+ ++D C D+ GGRC + G++ C C G
Sbjct: 422 RNLPGAYVCRCPAGFVGVHCE---TEVDAC-DSSPCQHGGRCESGGGAYLCVCPEGFF-- 475
Query: 237 PDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
C+ + + +S G C G++ C C GY
Sbjct: 476 --GYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY 512
Score = 59.3 bits (137), Expect = 4e-08
Identities = 70/262 (26%), Positives = 103/262 (39%), Gaps = 49/262 (18%)
Query: 327 DIDECAGGARPC-GGGQCRNTVGSYTCTCTD---GL--------VPSAAGAKPTCQDIDE 374
D+D+C+ PC GG C + VG+YTC C + GL VP A + P C +
Sbjct: 2 DVDDCSPD--PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAP-CHNGGT 58
Query: 375 CADLISTIIMMSVDE-LQKSVDPQIPELCGAGSCHNTIG--SFVCQCPDGYSVKPEQGPA 431
C D + + + ++P+ C + +G + +CQCP G+ G
Sbjct: 59 CVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFF-----GLL 113
Query: 432 CTDD---DECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHP 488
C + C + T C C+ GS+ C C A+ C N+ C
Sbjct: 114 CEFEITAMPCNMNT-QCPDGGYCMEHGGSYLCVCH---TDHNASHSLPSPC--NSDPCFN 167
Query: 489 RATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCEN-GHCSNTPGG 547
+C D S+ C C G+ G C + + C++ P C N G C G
Sbjct: 168 GGSCDAHDDSYTCECPRGFHGKH-------CEKARPHL--CSSGP--CRNGGTCKEAGGE 216
Query: 548 YECDCDVGFTRAADGRSC-LGK 568
Y C C FT GR C +GK
Sbjct: 217 YHCSCPYRFT----GRHCEIGK 234
Score = 41.9 bits (94), Expect = 0.006
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 7/84 (8%)
Query: 116 QMEVNECAAFPGLCGHG-RCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG 174
+ EV+ C + P C HG RC + G + C C G+ + C V++ G G
Sbjct: 442 ETEVDACDSSP--CQHGGRCESGGGAYLCVCPEGFF----GYHCETVSDPCFSSPCGGRG 495
Query: 175 DCHNTEGSFTCHCRPGYKADDFSK 198
C + GS +C C+ GY +D +K
Sbjct: 496 YCLASNGSHSCTCKVGYTGEDCAK 519
>Y13341-1|CAA73785.1| 310|Homo sapiens matrilin-3 precursor
protein.
Length = 310
Score = 105 bits (251), Expect = 6e-22
Identities = 56/187 (29%), Positives = 82/187 (43%), Gaps = 3/187 (1%)
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
F + +D C C+ + G CEC G L D+ +C +D C++ + C
Sbjct: 82 FQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGC 141
Query: 256 SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVN-TPGSYHCTCRE 314
+ ++ G+Y C C EGY + + CQH CVN GS+HC C E
Sbjct: 142 EHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYE 201
Query: 315 GWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDE 374
G+ L AD ++C D+CA G+ C + SY C C G + K TC +E
Sbjct: 202 GYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNE--DKKTCSATEE 259
Query: 375 CADLIST 381
L+ST
Sbjct: 260 ARRLVST 266
Score = 98.7 bits (235), Expect = 5e-20
Identities = 51/153 (33%), Positives = 71/153 (46%), Gaps = 3/153 (1%)
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNT-AGSFRCECGHGMELAPD 238
EG C C GY + K C +D CA N C CVN +GS+ CEC G L D
Sbjct: 108 EGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-ICVNDRSGSYHCECYEGYTLNED 166
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
R +C D+C++ + C + ++ G++ C C EGY + K CQ
Sbjct: 167 RKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQ 226
Query: 299 HSCVNT-PGSYHCTCREGWHLRADGRSCRDIDE 330
H CV+ SYHC C G+ L D ++C +E
Sbjct: 227 HICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 259
Score = 82.2 bits (194), Expect = 4e-15
Identities = 47/160 (29%), Positives = 73/160 (45%), Gaps = 7/160 (4%)
Query: 122 CAAFPGLCGHGRCRNLL-----GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
CA P + G +C+++ G C+C GY ++ TC ++ C + C
Sbjct: 87 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 146
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVN-TAGSFRCECGHGMEL 235
++ GS+ C C GY ++ K C D+CA C+ CVN GS CEC G L
Sbjct: 147 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQ-HICVNDRTGSHHCECYEGYTL 205
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
D+ +C D+C++ S C + + +Y C C GY
Sbjct: 206 NADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGY 245
Score = 71.7 bits (168), Expect = 6e-12
Identities = 48/158 (30%), Positives = 69/158 (43%), Gaps = 16/158 (10%)
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCIN-LPGSFQCRCRDGW--RG 468
G C+C GY++ ++ C+ D C L T C C+N GS+ C C +G+
Sbjct: 109 GKHHCECSQGYTLNADK-KTCSALDRCALNTHGCEHI--CVNDRSGSYHCECYEGYTLNE 165
Query: 469 DGATCEDVDECLTNNGGCHPRATCANT-DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
D TC D+C GC + C N GS C C GY + + C V D
Sbjct: 166 DRKTCSAQDKCALGTHGC--QHICVNDRTGSHHCECYEGYTLNAD--KKTCSVR-----D 216
Query: 528 ECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+CA C++ S+ Y CDC G+T D ++C
Sbjct: 217 KCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 254
Score = 63.3 bits (147), Expect = 2e-09
Identities = 34/129 (26%), Positives = 55/129 (42%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
++ CA C H + G + C+C+ GY + TC ++C + C ++
Sbjct: 131 LDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVND 190
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
GS C C GY + K C D+CA C+ + A S+ C+C G L D
Sbjct: 191 RTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNED 250
Query: 239 RLSCKDIDE 247
+ +C +E
Sbjct: 251 KKTCSATEE 259
Score = 60.9 bits (141), Expect = 1e-08
Identities = 42/134 (31%), Positives = 57/134 (42%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINL-PGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATC 492
D C LGT C CI+ G C C G+ D TC +D C N GC C
Sbjct: 90 DPCVLGTHQCQHV--CISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH--IC 145
Query: 493 ANT-DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
N GS+ C C GY + R C D+CA C++ ++ G + C+
Sbjct: 146 VNDRSGSYHCECYEGYTLNED--RKTCSAQ-----DKCALGTHGCQHICVNDRTGSHHCE 198
Query: 552 CDVGFTRAADGRSC 565
C G+T AD ++C
Sbjct: 199 CYEGYTLNADKKTC 212
Score = 38.7 bits (86), Expect = 0.054
Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
+D C+ C ++ +G C C GY + +T C +D CA +
Sbjct: 89 LDPCVLGTHQCQ-HVCISDGEGKHHCECSQGYTLNA-DKKT------CSALDRCALNTHG 140
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
CE+ ++ G Y C+C G+T D ++C
Sbjct: 141 CEHICVNDRSGSYHCECYEGYTLNEDRKTC 170
>X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein.
Length = 1246
Score = 105 bits (251), Expect = 6e-22
Identities = 64/171 (37%), Positives = 81/171 (47%), Gaps = 34/171 (19%)
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CH 408
+TC C+ G G TC DIDEC++ P +CG+ + C+
Sbjct: 692 FTCECSIGF----RGDGRTCYDIDECSEQ--------------------PSVCGSHTICN 727
Query: 409 NTIGSFVCQCPDGYSVKPEQGPACTDDDE----CELG--TCDCHPAADCINLPGS-FQCR 461
N G+F C+C +GY E D CE G CD A CI GS + C
Sbjct: 728 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 787
Query: 462 CRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
C G+ GDG C+DVDEC + CHP A C NT GSF C C GY+GDG+
Sbjct: 788 CLPGFSGDGQACQDVDECQPSR--CHPDAFCYNTPGSFTCQCKPGYQGDGF 836
Score = 93.9 bits (223), Expect = 1e-18
Identities = 62/183 (33%), Positives = 86/183 (46%), Gaps = 28/183 (15%)
Query: 297 CQHSCVNTPG---SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTC 352
C + PG + C C G+ R DGR+C DIDEC+ CG C N G++ C
Sbjct: 678 CDTNAACRPGPRTQFTCECSIGF--RGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRC 735
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV-DPQIPELCGAGSCHNTI 411
C +G S G TC ++ + ++ + + + IP+ C T
Sbjct: 736 ECVEGYQFSDEG---TC---------VAVVDQRPINYCETGLHNCDIPQ---RAQCIYTG 780
Query: 412 GS-FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
GS + C C G+S G AC D DEC+ C HP A C N PGSF C+C+ G++GDG
Sbjct: 781 GSSYTCSCLPGFS---GDGQACQDVDECQPSRC--HPDAFCYNTPGSFTCQCKPGYQGDG 835
Query: 471 ATC 473
C
Sbjct: 836 FRC 838
Score = 84.2 bits (199), Expect = 1e-15
Identities = 55/164 (33%), Positives = 73/164 (44%), Gaps = 27/164 (16%)
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDGAT 472
F C+C G+ G C D DEC C C N PG+F+C C +G++ D T
Sbjct: 692 FTCECSIGFR---GDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGT 748
Query: 473 C------EDVDECLTNNGGCH--PRATCANTDG-SFRCLCDTGYKGDGYGLRTVCCVYSC 523
C ++ C T C RA C T G S+ C C G+ GDG +C
Sbjct: 749 CVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDG---------QAC 799
Query: 524 VDIDECANDPTLCE-NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
D+DEC P+ C + C NTPG + C C G+ DG C+
Sbjct: 800 QDVDEC--QPSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRCV 839
Score = 83.8 bits (198), Expect = 1e-15
Identities = 71/237 (29%), Positives = 96/237 (40%), Gaps = 28/237 (11%)
Query: 208 DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGT 266
D +A CR G F CEC G D +C DIDECS +C S+ C N GT
Sbjct: 679 DTNAACRPG----PRTQFTCECSIGFR--GDGRTCYDIDECSEQPSVCGSHTICNNHPGT 732
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXX-----XXXXXRC----QHSCVNTPGS-YHCTCREGW 316
++C C EGY S + C + C+ T GS Y C+C G+
Sbjct: 733 FRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF 792
Query: 317 HLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECA 376
DG++C+D+DEC +R C NT GS+TC C G P + C
Sbjct: 793 S--GDGQACQDVDECQP-SRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQ 849
Query: 377 DLISTII-MMSVDELQKSVDPQ--IPELCGAG-----SCHNTIGSFVCQCPDGYSVK 425
I+ + Q+ + P +PE G CH + G C DG V+
Sbjct: 850 HEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVE 906
Score = 79.8 bits (188), Expect = 2e-14
Identities = 47/145 (32%), Positives = 69/145 (47%), Gaps = 15/145 (10%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYKADDFSKI 199
FTC+C G+ D + TC D++EC VCG C+N G+F C C GY+ D
Sbjct: 692 FTCECSIGFRGDGR--TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTC 749
Query: 200 CVDIDE-----C---ADNDALCRGGRCVNTAG-SFRCECGHGMELAPDRLSCKDIDECSI 250
+D+ C N + + +C+ T G S+ C C G + D +C+D+DEC
Sbjct: 750 VAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPG--FSGDGQACQDVDECQ- 806
Query: 251 TSGICSNGACENQMGTYQCVCDEGY 275
S + C N G++ C C GY
Sbjct: 807 PSRCHPDAFCYNTPGSFTCQCKPGY 831
Score = 78.6 bits (185), Expect = 5e-14
Identities = 48/133 (36%), Positives = 59/133 (44%), Gaps = 9/133 (6%)
Query: 438 CELGTCDCHPAADCINLPGS-FQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTD 496
C +GT C A C P + F C C G+RGDG TC D+DEC C C N
Sbjct: 671 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHP 730
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC---ENGHCSNTPG-GYECDC 552
G+FRC C GY+ G T V I+ C C + C T G Y C C
Sbjct: 731 GTFRCECVEGYQFSDEG--TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSC 788
Query: 553 DVGFTRAADGRSC 565
GF + DG++C
Sbjct: 789 LPGF--SGDGQAC 799
Score = 74.1 bits (174), Expect = 1e-12
Identities = 47/129 (36%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCV------DVNECEIVDGV 170
+++EC+ P +CG H C N G F C+C GY+ S TCV +N CE
Sbjct: 709 DIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQ-FSDEGTCVAVVDQRPINYCETGLHN 767
Query: 171 CG---DGDCHNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSF 225
C C T G S+TC C PG+ D + C D+DEC + C C NT GSF
Sbjct: 768 CDIPQRAQCIYTGGSSYTCSCLPGFSGD--GQACQDVDEC--QPSRCHPDAFCYNTPGSF 823
Query: 226 RCECGHGME 234
C+C G +
Sbjct: 824 TCQCKPGYQ 832
Score = 66.5 bits (155), Expect = 2e-10
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 18/154 (11%)
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGMELAPDRLS 241
FTC C G++ D + C DIDEC++ ++C C N G+FRCEC G + + +
Sbjct: 692 FTCECSIGFRGD--GRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTC 749
Query: 242 CKDIDECSITSGICSNGA--CENQMGTYQCVCDEGYAQS-TVKSHXXXXXXXXXXXXRCQ 298
+D+ I C G C+ QC+ G + + + CQ
Sbjct: 750 VAVVDQRPIN--YCETGLHNCDIPQRA-QCIYTGGSSYTCSCLPGFSGDGQACQDVDECQ 806
Query: 299 HS-------CVNTPGSYHCTCREGWHLRADGRSC 325
S C NTPGS+ C C+ G+ + DG C
Sbjct: 807 PSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRC 838
Score = 62.5 bits (145), Expect = 4e-09
Identities = 60/211 (28%), Positives = 79/211 (37%), Gaps = 42/211 (19%)
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSI-TSGICSNGACENQMGT-YQCVCDEGYAQSTVK 281
+F G E +PD L + C I T G +N AC T + C C G+
Sbjct: 651 AFSNSIGPVREGSPDALQ----NPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRT 706
Query: 282 SHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDE-----CAGGAR 336
+ C N PG++ C C EG+ +G +D+ C G
Sbjct: 707 CYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLH 766
Query: 337 PCG---GGQCRNTVGS-YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQK 392
C QC T GS YTC+C +P +G CQD+DEC
Sbjct: 767 NCDIPQRAQCIYTGGSSYTCSC----LPGFSGDGQACQDVDECQ---------------- 806
Query: 393 SVDPQIPELCGAGS-CHNTIGSFVCQCPDGY 422
P C + C+NT GSF CQC GY
Sbjct: 807 ------PSRCHPDAFCYNTPGSFTCQCKPGY 831
Score = 62.5 bits (145), Expect = 4e-09
Identities = 27/66 (40%), Positives = 40/66 (60%), Gaps = 5/66 (7%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGDCHNTEGSFTCHCRPGYKADDFSKI 199
+TC C PG+ D + C DV+EC+ C D C+NT GSFTC C+PGY+ D F +
Sbjct: 784 YTCSCLPGFSGDGQ--ACQDVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV 839
Query: 200 CVDIDE 205
++++
Sbjct: 840 PGEVEK 845
Score = 32.7 bits (71), Expect = 3.6
Identities = 16/36 (44%), Positives = 19/36 (52%), Gaps = 3/36 (8%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD 152
+V+EC P C C N G FTC C PGY+ D
Sbjct: 801 DVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGD 834
>M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein.
Length = 1247
Score = 105 bits (251), Expect = 6e-22
Identities = 64/171 (37%), Positives = 81/171 (47%), Gaps = 34/171 (19%)
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CH 408
+TC C+ G G TC DIDEC++ P +CG+ + C+
Sbjct: 693 FTCECSIGF----RGDGRTCYDIDECSEQ--------------------PSVCGSHTICN 728
Query: 409 NTIGSFVCQCPDGYSVKPEQGPACTDDDE----CELG--TCDCHPAADCINLPGS-FQCR 461
N G+F C+C +GY E D CE G CD A CI GS + C
Sbjct: 729 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 788
Query: 462 CRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
C G+ GDG C+DVDEC + CHP A C NT GSF C C GY+GDG+
Sbjct: 789 CLPGFSGDGQACQDVDECQPSR--CHPDAFCYNTPGSFTCQCKPGYQGDGF 837
Score = 93.9 bits (223), Expect = 1e-18
Identities = 62/183 (33%), Positives = 86/183 (46%), Gaps = 28/183 (15%)
Query: 297 CQHSCVNTPG---SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTC 352
C + PG + C C G+ R DGR+C DIDEC+ CG C N G++ C
Sbjct: 679 CDTNAACRPGPRTQFTCECSIGF--RGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRC 736
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV-DPQIPELCGAGSCHNTI 411
C +G S G TC ++ + ++ + + + IP+ C T
Sbjct: 737 ECVEGYQFSDEG---TC---------VAVVDQRPINYCETGLHNCDIPQ---RAQCIYTG 781
Query: 412 GS-FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
GS + C C G+S G AC D DEC+ C HP A C N PGSF C+C+ G++GDG
Sbjct: 782 GSSYTCSCLPGFS---GDGQACQDVDECQPSRC--HPDAFCYNTPGSFTCQCKPGYQGDG 836
Query: 471 ATC 473
C
Sbjct: 837 FRC 839
Score = 84.2 bits (199), Expect = 1e-15
Identities = 55/164 (33%), Positives = 73/164 (44%), Gaps = 27/164 (16%)
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDGAT 472
F C+C G+ G C D DEC C C N PG+F+C C +G++ D T
Sbjct: 693 FTCECSIGFR---GDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGT 749
Query: 473 C------EDVDECLTNNGGCH--PRATCANTDG-SFRCLCDTGYKGDGYGLRTVCCVYSC 523
C ++ C T C RA C T G S+ C C G+ GDG +C
Sbjct: 750 CVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDG---------QAC 800
Query: 524 VDIDECANDPTLCE-NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
D+DEC P+ C + C NTPG + C C G+ DG C+
Sbjct: 801 QDVDEC--QPSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRCV 840
Score = 83.8 bits (198), Expect = 1e-15
Identities = 71/237 (29%), Positives = 96/237 (40%), Gaps = 28/237 (11%)
Query: 208 DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGT 266
D +A CR G F CEC G D +C DIDECS +C S+ C N GT
Sbjct: 680 DTNAACRPG----PRTQFTCECSIGFR--GDGRTCYDIDECSEQPSVCGSHTICNNHPGT 733
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXX-----XXXXXRC----QHSCVNTPGS-YHCTCREGW 316
++C C EGY S + C + C+ T GS Y C+C G+
Sbjct: 734 FRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF 793
Query: 317 HLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECA 376
DG++C+D+DEC +R C NT GS+TC C G P + C
Sbjct: 794 S--GDGQACQDVDECQP-SRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQ 850
Query: 377 DLISTII-MMSVDELQKSVDPQ--IPELCGAG-----SCHNTIGSFVCQCPDGYSVK 425
I+ + Q+ + P +PE G CH + G C DG V+
Sbjct: 851 HEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVE 907
Score = 79.8 bits (188), Expect = 2e-14
Identities = 47/145 (32%), Positives = 69/145 (47%), Gaps = 15/145 (10%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYKADDFSKI 199
FTC+C G+ D + TC D++EC VCG C+N G+F C C GY+ D
Sbjct: 693 FTCECSIGFRGDGR--TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTC 750
Query: 200 CVDIDE-----C---ADNDALCRGGRCVNTAG-SFRCECGHGMELAPDRLSCKDIDECSI 250
+D+ C N + + +C+ T G S+ C C G + D +C+D+DEC
Sbjct: 751 VAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPG--FSGDGQACQDVDECQ- 807
Query: 251 TSGICSNGACENQMGTYQCVCDEGY 275
S + C N G++ C C GY
Sbjct: 808 PSRCHPDAFCYNTPGSFTCQCKPGY 832
Score = 78.6 bits (185), Expect = 5e-14
Identities = 48/133 (36%), Positives = 59/133 (44%), Gaps = 9/133 (6%)
Query: 438 CELGTCDCHPAADCINLPGS-FQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTD 496
C +GT C A C P + F C C G+RGDG TC D+DEC C C N
Sbjct: 672 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHP 731
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC---ENGHCSNTPG-GYECDC 552
G+FRC C GY+ G T V I+ C C + C T G Y C C
Sbjct: 732 GTFRCECVEGYQFSDEG--TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSC 789
Query: 553 DVGFTRAADGRSC 565
GF + DG++C
Sbjct: 790 LPGF--SGDGQAC 800
Score = 74.1 bits (174), Expect = 1e-12
Identities = 47/129 (36%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCV------DVNECEIVDGV 170
+++EC+ P +CG H C N G F C+C GY+ S TCV +N CE
Sbjct: 710 DIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQ-FSDEGTCVAVVDQRPINYCETGLHN 768
Query: 171 CG---DGDCHNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSF 225
C C T G S+TC C PG+ D + C D+DEC + C C NT GSF
Sbjct: 769 CDIPQRAQCIYTGGSSYTCSCLPGFSGD--GQACQDVDEC--QPSRCHPDAFCYNTPGSF 824
Query: 226 RCECGHGME 234
C+C G +
Sbjct: 825 TCQCKPGYQ 833
Score = 66.5 bits (155), Expect = 2e-10
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 18/154 (11%)
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGMELAPDRLS 241
FTC C G++ D + C DIDEC++ ++C C N G+FRCEC G + + +
Sbjct: 693 FTCECSIGFRGD--GRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTC 750
Query: 242 CKDIDECSITSGICSNGA--CENQMGTYQCVCDEGYAQS-TVKSHXXXXXXXXXXXXRCQ 298
+D+ I C G C+ QC+ G + + + CQ
Sbjct: 751 VAVVDQRPIN--YCETGLHNCDIPQRA-QCIYTGGSSYTCSCLPGFSGDGQACQDVDECQ 807
Query: 299 HS-------CVNTPGSYHCTCREGWHLRADGRSC 325
S C NTPGS+ C C+ G+ + DG C
Sbjct: 808 PSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRC 839
Score = 62.5 bits (145), Expect = 4e-09
Identities = 60/211 (28%), Positives = 79/211 (37%), Gaps = 42/211 (19%)
Query: 224 SFRCECGHGMELAPDRLSCKDIDECSI-TSGICSNGACENQMGT-YQCVCDEGYAQSTVK 281
+F G E +PD L + C I T G +N AC T + C C G+
Sbjct: 652 AFSNSIGPVREGSPDALQ----NPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRT 707
Query: 282 SHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDE-----CAGGAR 336
+ C N PG++ C C EG+ +G +D+ C G
Sbjct: 708 CYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLH 767
Query: 337 PCG---GGQCRNTVGS-YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQK 392
C QC T GS YTC+C +P +G CQD+DEC
Sbjct: 768 NCDIPQRAQCIYTGGSSYTCSC----LPGFSGDGQACQDVDECQ---------------- 807
Query: 393 SVDPQIPELCGAGS-CHNTIGSFVCQCPDGY 422
P C + C+NT GSF CQC GY
Sbjct: 808 ------PSRCHPDAFCYNTPGSFTCQCKPGY 832
Score = 62.5 bits (145), Expect = 4e-09
Identities = 27/66 (40%), Positives = 40/66 (60%), Gaps = 5/66 (7%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGDCHNTEGSFTCHCRPGYKADDFSKI 199
+TC C PG+ D + C DV+EC+ C D C+NT GSFTC C+PGY+ D F +
Sbjct: 785 YTCSCLPGFSGDGQ--ACQDVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV 840
Query: 200 CVDIDE 205
++++
Sbjct: 841 PGEVEK 846
Score = 32.7 bits (71), Expect = 3.6
Identities = 16/36 (44%), Positives = 19/36 (52%), Gaps = 3/36 (8%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD 152
+V+EC P C C N G FTC C PGY+ D
Sbjct: 802 DVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGD 835
>M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein.
Length = 581
Score = 105 bits (251), Expect = 6e-22
Identities = 64/171 (37%), Positives = 81/171 (47%), Gaps = 34/171 (19%)
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CH 408
+TC C+ G G TC DIDEC++ P +CG+ + C+
Sbjct: 27 FTCECSIGF----RGDGRTCYDIDECSEQ--------------------PSVCGSHTICN 62
Query: 409 NTIGSFVCQCPDGYSVKPEQGPACTDDDE----CELG--TCDCHPAADCINLPGS-FQCR 461
N G+F C+C +GY E D CE G CD A CI GS + C
Sbjct: 63 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 122
Query: 462 CRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
C G+ GDG C+DVDEC + CHP A C NT GSF C C GY+GDG+
Sbjct: 123 CLPGFSGDGQACQDVDECQPSR--CHPDAFCYNTPGSFTCQCKPGYQGDGF 171
Score = 93.9 bits (223), Expect = 1e-18
Identities = 62/183 (33%), Positives = 86/183 (46%), Gaps = 28/183 (15%)
Query: 297 CQHSCVNTPG---SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTC 352
C + PG + C C G+ R DGR+C DIDEC+ CG C N G++ C
Sbjct: 13 CDTNAACRPGPRTQFTCECSIGF--RGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRC 70
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV-DPQIPELCGAGSCHNTI 411
C +G S G TC ++ + ++ + + + IP+ C T
Sbjct: 71 ECVEGYQFSDEG---TC---------VAVVDQRPINYCETGLHNCDIPQ---RAQCIYTG 115
Query: 412 GS-FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
GS + C C G+S G AC D DEC+ C HP A C N PGSF C+C+ G++GDG
Sbjct: 116 GSSYTCSCLPGFS---GDGQACQDVDECQPSRC--HPDAFCYNTPGSFTCQCKPGYQGDG 170
Query: 471 ATC 473
C
Sbjct: 171 FRC 173
Score = 84.2 bits (199), Expect = 1e-15
Identities = 55/164 (33%), Positives = 73/164 (44%), Gaps = 27/164 (16%)
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDGAT 472
F C+C G+ G C D DEC C C N PG+F+C C +G++ D T
Sbjct: 27 FTCECSIGFR---GDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGT 83
Query: 473 C------EDVDECLTNNGGCH--PRATCANTDG-SFRCLCDTGYKGDGYGLRTVCCVYSC 523
C ++ C T C RA C T G S+ C C G+ GDG +C
Sbjct: 84 CVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDG---------QAC 134
Query: 524 VDIDECANDPTLCE-NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
D+DEC P+ C + C NTPG + C C G+ DG C+
Sbjct: 135 QDVDEC--QPSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRCV 174
Score = 83.8 bits (198), Expect = 1e-15
Identities = 71/237 (29%), Positives = 96/237 (40%), Gaps = 28/237 (11%)
Query: 208 DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGT 266
D +A CR G F CEC G D +C DIDECS +C S+ C N GT
Sbjct: 14 DTNAACRPG----PRTQFTCECSIGFR--GDGRTCYDIDECSEQPSVCGSHTICNNHPGT 67
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXX-----XXXXXRC----QHSCVNTPGS-YHCTCREGW 316
++C C EGY S + C + C+ T GS Y C+C G+
Sbjct: 68 FRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF 127
Query: 317 HLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECA 376
DG++C+D+DEC +R C NT GS+TC C G P + C
Sbjct: 128 S--GDGQACQDVDECQP-SRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQ 184
Query: 377 DLISTII-MMSVDELQKSVDPQ--IPELCGAG-----SCHNTIGSFVCQCPDGYSVK 425
I+ + Q+ + P +PE G CH + G C DG V+
Sbjct: 185 HEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVE 241
Score = 79.8 bits (188), Expect = 2e-14
Identities = 47/145 (32%), Positives = 69/145 (47%), Gaps = 15/145 (10%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYKADDFSKI 199
FTC+C G+ D + TC D++EC VCG C+N G+F C C GY+ D
Sbjct: 27 FTCECSIGFRGDGR--TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTC 84
Query: 200 CVDIDE-----C---ADNDALCRGGRCVNTAG-SFRCECGHGMELAPDRLSCKDIDECSI 250
+D+ C N + + +C+ T G S+ C C G + D +C+D+DEC
Sbjct: 85 VAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPG--FSGDGQACQDVDECQ- 141
Query: 251 TSGICSNGACENQMGTYQCVCDEGY 275
S + C N G++ C C GY
Sbjct: 142 PSRCHPDAFCYNTPGSFTCQCKPGY 166
Score = 78.6 bits (185), Expect = 5e-14
Identities = 48/133 (36%), Positives = 59/133 (44%), Gaps = 9/133 (6%)
Query: 438 CELGTCDCHPAADCINLPGS-FQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTD 496
C +GT C A C P + F C C G+RGDG TC D+DEC C C N
Sbjct: 6 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHP 65
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC---ENGHCSNTPG-GYECDC 552
G+FRC C GY+ G T V I+ C C + C T G Y C C
Sbjct: 66 GTFRCECVEGYQFSDEG--TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSC 123
Query: 553 DVGFTRAADGRSC 565
GF + DG++C
Sbjct: 124 LPGF--SGDGQAC 134
Score = 74.1 bits (174), Expect = 1e-12
Identities = 47/129 (36%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCV------DVNECEIVDGV 170
+++EC+ P +CG H C N G F C+C GY+ S TCV +N CE
Sbjct: 44 DIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQ-FSDEGTCVAVVDQRPINYCETGLHN 102
Query: 171 CG---DGDCHNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSF 225
C C T G S+TC C PG+ D + C D+DEC + C C NT GSF
Sbjct: 103 CDIPQRAQCIYTGGSSYTCSCLPGFSGD--GQACQDVDEC--QPSRCHPDAFCYNTPGSF 158
Query: 226 RCECGHGME 234
C+C G +
Sbjct: 159 TCQCKPGYQ 167
Score = 66.5 bits (155), Expect = 2e-10
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 18/154 (11%)
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGMELAPDRLS 241
FTC C G++ D + C DIDEC++ ++C C N G+FRCEC G + + +
Sbjct: 27 FTCECSIGFRGD--GRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTC 84
Query: 242 CKDIDECSITSGICSNGA--CENQMGTYQCVCDEGYAQS-TVKSHXXXXXXXXXXXXRCQ 298
+D+ I C G C+ QC+ G + + + CQ
Sbjct: 85 VAVVDQRPIN--YCETGLHNCDIPQRA-QCIYTGGSSYTCSCLPGFSGDGQACQDVDECQ 141
Query: 299 HS-------CVNTPGSYHCTCREGWHLRADGRSC 325
S C NTPGS+ C C+ G+ + DG C
Sbjct: 142 PSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRC 173
Score = 62.5 bits (145), Expect = 4e-09
Identities = 27/66 (40%), Positives = 40/66 (60%), Gaps = 5/66 (7%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGDCHNTEGSFTCHCRPGYKADDFSKI 199
+TC C PG+ D + C DV+EC+ C D C+NT GSFTC C+PGY+ D F +
Sbjct: 119 YTCSCLPGFSGDGQ--ACQDVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV 174
Query: 200 CVDIDE 205
++++
Sbjct: 175 PGEVEK 180
Score = 61.3 bits (142), Expect = 9e-09
Identities = 52/183 (28%), Positives = 68/183 (37%), Gaps = 37/183 (20%)
Query: 251 TSGICSNGACENQMGT-YQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYH 309
T G +N AC T + C C G+ + C N PG++
Sbjct: 10 THGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFR 69
Query: 310 CTCREGWHLRADGRSCRDIDE-----CAGGARPCG---GGQCRNTVGS-YTCTCTDGLVP 360
C C EG+ +G +D+ C G C QC T GS YTC+C +P
Sbjct: 70 CECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSC----LP 125
Query: 361 SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNTIGSFVCQCP 419
+G CQD+DEC P C + C+NT GSF CQC
Sbjct: 126 GFSGDGQACQDVDECQ----------------------PSRCHPDAFCYNTPGSFTCQCK 163
Query: 420 DGY 422
GY
Sbjct: 164 PGY 166
Score = 32.7 bits (71), Expect = 3.6
Identities = 16/36 (44%), Positives = 19/36 (52%), Gaps = 3/36 (8%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD 152
+V+EC P C C N G FTC C PGY+ D
Sbjct: 136 DVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGD 169
>BC139907-1|AAI39908.1| 486|Homo sapiens matrilin 3 protein.
Length = 486
Score = 105 bits (251), Expect = 6e-22
Identities = 56/187 (29%), Positives = 82/187 (43%), Gaps = 3/187 (1%)
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
F + +D C C+ + G CEC G L D+ +C +D C++ + C
Sbjct: 258 FQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGC 317
Query: 256 SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVN-TPGSYHCTCRE 314
+ ++ G+Y C C EGY + + CQH CVN GS+HC C E
Sbjct: 318 EHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYE 377
Query: 315 GWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDE 374
G+ L AD ++C D+CA G+ C + SY C C G + K TC +E
Sbjct: 378 GYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNE--DKKTCSATEE 435
Query: 375 CADLIST 381
L+ST
Sbjct: 436 ARRLVST 442
Score = 98.7 bits (235), Expect = 5e-20
Identities = 51/153 (33%), Positives = 71/153 (46%), Gaps = 3/153 (1%)
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNT-AGSFRCECGHGMELAPD 238
EG C C GY + K C +D CA N C CVN +GS+ CEC G L D
Sbjct: 284 EGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-ICVNDRSGSYHCECYEGYTLNED 342
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
R +C D+C++ + C + ++ G++ C C EGY + K CQ
Sbjct: 343 RKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQ 402
Query: 299 HSCVNT-PGSYHCTCREGWHLRADGRSCRDIDE 330
H CV+ SYHC C G+ L D ++C +E
Sbjct: 403 HICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
Score = 82.2 bits (194), Expect = 4e-15
Identities = 47/160 (29%), Positives = 73/160 (45%), Gaps = 7/160 (4%)
Query: 122 CAAFPGLCGHGRCRNLL-----GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
CA P + G +C+++ G C+C GY ++ TC ++ C + C
Sbjct: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVN-TAGSFRCECGHGMEL 235
++ GS+ C C GY ++ K C D+CA C+ CVN GS CEC G L
Sbjct: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQ-HICVNDRTGSHHCECYEGYTL 381
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
D+ +C D+C++ S C + + +Y C C GY
Sbjct: 382 NADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGY 421
Score = 71.7 bits (168), Expect = 6e-12
Identities = 48/158 (30%), Positives = 69/158 (43%), Gaps = 16/158 (10%)
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCIN-LPGSFQCRCRDGW--RG 468
G C+C GY++ ++ C+ D C L T C C+N GS+ C C +G+
Sbjct: 285 GKHHCECSQGYTLNADK-KTCSALDRCALNTHGCEHI--CVNDRSGSYHCECYEGYTLNE 341
Query: 469 DGATCEDVDECLTNNGGCHPRATCANT-DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
D TC D+C GC + C N GS C C GY + + C V D
Sbjct: 342 DRKTCSAQDKCALGTHGC--QHICVNDRTGSHHCECYEGYTLNAD--KKTCSVR-----D 392
Query: 528 ECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+CA C++ S+ Y CDC G+T D ++C
Sbjct: 393 KCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
Score = 63.3 bits (147), Expect = 2e-09
Identities = 34/129 (26%), Positives = 55/129 (42%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
++ CA C H + G + C+C+ GY + TC ++C + C ++
Sbjct: 307 LDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVND 366
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
GS C C GY + K C D+CA C+ + A S+ C+C G L D
Sbjct: 367 RTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNED 426
Query: 239 RLSCKDIDE 247
+ +C +E
Sbjct: 427 KKTCSATEE 435
Score = 60.9 bits (141), Expect = 1e-08
Identities = 42/134 (31%), Positives = 57/134 (42%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINL-PGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATC 492
D C LGT C CI+ G C C G+ D TC +D C N GC C
Sbjct: 266 DPCVLGTHQCQHV--CISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH--IC 321
Query: 493 ANT-DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
N GS+ C C GY + R C D+CA C++ ++ G + C+
Sbjct: 322 VNDRSGSYHCECYEGYTLNED--RKTCSAQ-----DKCALGTHGCQHICVNDRTGSHHCE 374
Query: 552 CDVGFTRAADGRSC 565
C G+T AD ++C
Sbjct: 375 CYEGYTLNADKKTC 388
Score = 38.7 bits (86), Expect = 0.054
Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
+D C+ C ++ +G C C GY + +T C +D CA +
Sbjct: 265 LDPCVLGTHQCQ-HVCISDGEGKHHCECSQGYTLNA-DKKT------CSALDRCALNTHG 316
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
CE+ ++ G Y C+C G+T D ++C
Sbjct: 317 CEHICVNDRSGSYHCECYEGYTLNEDRKTC 346
>AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein.
Length = 1247
Score = 105 bits (251), Expect = 6e-22
Identities = 64/171 (37%), Positives = 81/171 (47%), Gaps = 34/171 (19%)
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CH 408
+TC C+ G G TC DIDEC++ P +CG+ + C+
Sbjct: 693 FTCECSIGF----RGDGRTCYDIDECSEQ--------------------PSVCGSHTICN 728
Query: 409 NTIGSFVCQCPDGYSVKPEQGPACTDDDE----CELG--TCDCHPAADCINLPGS-FQCR 461
N G+F C+C +GY E D CE G CD A CI GS + C
Sbjct: 729 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 788
Query: 462 CRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
C G+ GDG C+DVDEC + CHP A C NT GSF C C GY+GDG+
Sbjct: 789 CLPGFSGDGQACQDVDECQPSR--CHPDAFCYNTPGSFTCQCKPGYQGDGF 837
Score = 93.9 bits (223), Expect = 1e-18
Identities = 62/183 (33%), Positives = 86/183 (46%), Gaps = 28/183 (15%)
Query: 297 CQHSCVNTPG---SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTC 352
C + PG + C C G+ R DGR+C DIDEC+ CG C N G++ C
Sbjct: 679 CDTNAACRPGPRTQFTCECSIGF--RGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRC 736
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV-DPQIPELCGAGSCHNTI 411
C +G S G TC ++ + ++ + + + IP+ C T
Sbjct: 737 ECVEGYQFSDEG---TC---------VAVVDQRPINYCETGLHNCDIPQ---RAQCIYTG 781
Query: 412 GS-FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
GS + C C G+S G AC D DEC+ C HP A C N PGSF C+C+ G++GDG
Sbjct: 782 GSSYTCSCLPGFS---GDGQACQDVDECQPSRC--HPDAFCYNTPGSFTCQCKPGYQGDG 836
Query: 471 ATC 473
C
Sbjct: 837 FRC 839
Score = 84.2 bits (199), Expect = 1e-15
Identities = 55/164 (33%), Positives = 73/164 (44%), Gaps = 27/164 (16%)
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDGAT 472
F C+C G+ G C D DEC C C N PG+F+C C +G++ D T
Sbjct: 693 FTCECSIGFR---GDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGT 749
Query: 473 C------EDVDECLTNNGGCH--PRATCANTDG-SFRCLCDTGYKGDGYGLRTVCCVYSC 523
C ++ C T C RA C T G S+ C C G+ GDG +C
Sbjct: 750 CVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDG---------QAC 800
Query: 524 VDIDECANDPTLCE-NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
D+DEC P+ C + C NTPG + C C G+ DG C+
Sbjct: 801 QDVDEC--QPSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRCV 840
Score = 83.8 bits (198), Expect = 1e-15
Identities = 71/237 (29%), Positives = 96/237 (40%), Gaps = 28/237 (11%)
Query: 208 DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGT 266
D +A CR G F CEC G D +C DIDECS +C S+ C N GT
Sbjct: 680 DTNAACRPG----PRTQFTCECSIGFR--GDGRTCYDIDECSEQPSVCGSHTICNNHPGT 733
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXX-----XXXXXRC----QHSCVNTPGS-YHCTCREGW 316
++C C EGY S + C + C+ T GS Y C+C G+
Sbjct: 734 FRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF 793
Query: 317 HLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECA 376
DG++C+D+DEC +R C NT GS+TC C G P + C
Sbjct: 794 S--GDGQACQDVDECQP-SRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQ 850
Query: 377 DLISTII-MMSVDELQKSVDPQ--IPELCGAG-----SCHNTIGSFVCQCPDGYSVK 425
I+ + Q+ + P +PE G CH + G C DG V+
Sbjct: 851 HEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVE 907
Score = 79.8 bits (188), Expect = 2e-14
Identities = 47/145 (32%), Positives = 69/145 (47%), Gaps = 15/145 (10%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYKADDFSKI 199
FTC+C G+ D + TC D++EC VCG C+N G+F C C GY+ D
Sbjct: 693 FTCECSIGFRGDGR--TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTC 750
Query: 200 CVDIDE-----C---ADNDALCRGGRCVNTAG-SFRCECGHGMELAPDRLSCKDIDECSI 250
+D+ C N + + +C+ T G S+ C C G + D +C+D+DEC
Sbjct: 751 VAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPG--FSGDGQACQDVDECQ- 807
Query: 251 TSGICSNGACENQMGTYQCVCDEGY 275
S + C N G++ C C GY
Sbjct: 808 PSRCHPDAFCYNTPGSFTCQCKPGY 832
Score = 78.6 bits (185), Expect = 5e-14
Identities = 48/133 (36%), Positives = 59/133 (44%), Gaps = 9/133 (6%)
Query: 438 CELGTCDCHPAADCINLPGS-FQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTD 496
C +GT C A C P + F C C G+RGDG TC D+DEC C C N
Sbjct: 672 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHP 731
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC---ENGHCSNTPG-GYECDC 552
G+FRC C GY+ G T V I+ C C + C T G Y C C
Sbjct: 732 GTFRCECVEGYQFSDEG--TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSC 789
Query: 553 DVGFTRAADGRSC 565
GF + DG++C
Sbjct: 790 LPGF--SGDGQAC 800
Score = 74.1 bits (174), Expect = 1e-12
Identities = 47/129 (36%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCV------DVNECEIVDGV 170
+++EC+ P +CG H C N G F C+C GY+ S TCV +N CE
Sbjct: 710 DIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQ-FSDEGTCVAVVDQRPINYCETGLHN 768
Query: 171 CG---DGDCHNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSF 225
C C T G S+TC C PG+ D + C D+DEC + C C NT GSF
Sbjct: 769 CDIPQRAQCIYTGGSSYTCSCLPGFSGD--GQACQDVDEC--QPSRCHPDAFCYNTPGSF 824
Query: 226 RCECGHGME 234
C+C G +
Sbjct: 825 TCQCKPGYQ 833
Score = 66.5 bits (155), Expect = 2e-10
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 18/154 (11%)
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGMELAPDRLS 241
FTC C G++ D + C DIDEC++ ++C C N G+FRCEC G + + +
Sbjct: 693 FTCECSIGFRGD--GRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTC 750
Query: 242 CKDIDECSITSGICSNGA--CENQMGTYQCVCDEGYAQS-TVKSHXXXXXXXXXXXXRCQ 298
+D+ I C G C+ QC+ G + + + CQ
Sbjct: 751 VAVVDQRPIN--YCETGLHNCDIPQRA-QCIYTGGSSYTCSCLPGFSGDGQACQDVDECQ 807
Query: 299 HS-------CVNTPGSYHCTCREGWHLRADGRSC 325
S C NTPGS+ C C+ G+ + DG C
Sbjct: 808 PSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRC 839
Score = 62.5 bits (145), Expect = 4e-09
Identities = 27/66 (40%), Positives = 40/66 (60%), Gaps = 5/66 (7%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGDCHNTEGSFTCHCRPGYKADDFSKI 199
+TC C PG+ D + C DV+EC+ C D C+NT GSFTC C+PGY+ D F +
Sbjct: 785 YTCSCLPGFSGDGQ--ACQDVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV 840
Query: 200 CVDIDE 205
++++
Sbjct: 841 PGEVEK 846
Score = 61.7 bits (143), Expect = 7e-09
Identities = 58/201 (28%), Positives = 76/201 (37%), Gaps = 42/201 (20%)
Query: 234 ELAPDRLSCKDIDECSI-TSGICSNGACENQMGT-YQCVCDEGYAQSTVKSHXXXXXXXX 291
E +PD L + C I T G +N AC T + C C G+ +
Sbjct: 662 EGSPDALQ----NPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQ 717
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDE-----CAGGARPCG---GGQC 343
C N PG++ C C EG+ +G +D+ C G C QC
Sbjct: 718 PSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQC 777
Query: 344 RNTVGS-YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
T GS YTC+C +P +G CQD+DEC P C
Sbjct: 778 IYTGGSSYTCSC----LPGFSGDGQACQDVDECQ----------------------PSRC 811
Query: 403 GAGS-CHNTIGSFVCQCPDGY 422
+ C+NT GSF CQC GY
Sbjct: 812 HPDAFCYNTPGSFTCQCKPGY 832
Score = 32.7 bits (71), Expect = 3.6
Identities = 16/36 (44%), Positives = 19/36 (52%), Gaps = 3/36 (8%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD 152
+V+EC P C C N G FTC C PGY+ D
Sbjct: 802 DVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGD 835
>AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein.
Length = 1247
Score = 105 bits (251), Expect = 6e-22
Identities = 64/171 (37%), Positives = 81/171 (47%), Gaps = 34/171 (19%)
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CH 408
+TC C+ G G TC DIDEC++ P +CG+ + C+
Sbjct: 693 FTCECSIGF----RGDGRTCYDIDECSEQ--------------------PSVCGSHTICN 728
Query: 409 NTIGSFVCQCPDGYSVKPEQGPACTDDDE----CELG--TCDCHPAADCINLPGS-FQCR 461
N G+F C+C +GY E D CE G CD A CI GS + C
Sbjct: 729 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 788
Query: 462 CRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
C G+ GDG C+DVDEC + CHP A C NT GSF C C GY+GDG+
Sbjct: 789 CLPGFSGDGQACQDVDECQPSR--CHPDAFCYNTPGSFTCQCKPGYQGDGF 837
Score = 93.9 bits (223), Expect = 1e-18
Identities = 62/183 (33%), Positives = 86/183 (46%), Gaps = 28/183 (15%)
Query: 297 CQHSCVNTPG---SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTC 352
C + PG + C C G+ R DGR+C DIDEC+ CG C N G++ C
Sbjct: 679 CDTNAACRPGPRTQFTCECSIGF--RGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRC 736
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV-DPQIPELCGAGSCHNTI 411
C +G S G TC ++ + ++ + + + IP+ C T
Sbjct: 737 ECVEGYQFSDEG---TC---------VAVVDQRPINYCETGLHNCDIPQ---RAQCIYTG 781
Query: 412 GS-FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
GS + C C G+S G AC D DEC+ C HP A C N PGSF C+C+ G++GDG
Sbjct: 782 GSSYTCSCLPGFS---GDGQACQDVDECQPSRC--HPDAFCYNTPGSFTCQCKPGYQGDG 836
Query: 471 ATC 473
C
Sbjct: 837 FRC 839
Score = 84.2 bits (199), Expect = 1e-15
Identities = 55/164 (33%), Positives = 73/164 (44%), Gaps = 27/164 (16%)
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDGAT 472
F C+C G+ G C D DEC C C N PG+F+C C +G++ D T
Sbjct: 693 FTCECSIGFR---GDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGT 749
Query: 473 C------EDVDECLTNNGGCH--PRATCANTDG-SFRCLCDTGYKGDGYGLRTVCCVYSC 523
C ++ C T C RA C T G S+ C C G+ GDG +C
Sbjct: 750 CVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDG---------QAC 800
Query: 524 VDIDECANDPTLCE-NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
D+DEC P+ C + C NTPG + C C G+ DG C+
Sbjct: 801 QDVDEC--QPSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRCV 840
Score = 83.8 bits (198), Expect = 1e-15
Identities = 71/237 (29%), Positives = 96/237 (40%), Gaps = 28/237 (11%)
Query: 208 DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGT 266
D +A CR G F CEC G D +C DIDECS +C S+ C N GT
Sbjct: 680 DTNAACRPG----PRTQFTCECSIGFR--GDGRTCYDIDECSEQPSVCGSHTICNNHPGT 733
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXX-----XXXXXRC----QHSCVNTPGS-YHCTCREGW 316
++C C EGY S + C + C+ T GS Y C+C G+
Sbjct: 734 FRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF 793
Query: 317 HLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECA 376
DG++C+D+DEC +R C NT GS+TC C G P + C
Sbjct: 794 S--GDGQACQDVDECQP-SRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQ 850
Query: 377 DLISTII-MMSVDELQKSVDPQ--IPELCGAG-----SCHNTIGSFVCQCPDGYSVK 425
I+ + Q+ + P +PE G CH + G C DG V+
Sbjct: 851 HEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVE 907
Score = 79.8 bits (188), Expect = 2e-14
Identities = 47/145 (32%), Positives = 69/145 (47%), Gaps = 15/145 (10%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYKADDFSKI 199
FTC+C G+ D + TC D++EC VCG C+N G+F C C GY+ D
Sbjct: 693 FTCECSIGFRGDGR--TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTC 750
Query: 200 CVDIDE-----C---ADNDALCRGGRCVNTAG-SFRCECGHGMELAPDRLSCKDIDECSI 250
+D+ C N + + +C+ T G S+ C C G + D +C+D+DEC
Sbjct: 751 VAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPG--FSGDGQACQDVDECQ- 807
Query: 251 TSGICSNGACENQMGTYQCVCDEGY 275
S + C N G++ C C GY
Sbjct: 808 PSRCHPDAFCYNTPGSFTCQCKPGY 832
Score = 78.6 bits (185), Expect = 5e-14
Identities = 48/133 (36%), Positives = 59/133 (44%), Gaps = 9/133 (6%)
Query: 438 CELGTCDCHPAADCINLPGS-FQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTD 496
C +GT C A C P + F C C G+RGDG TC D+DEC C C N
Sbjct: 672 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHP 731
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC---ENGHCSNTPG-GYECDC 552
G+FRC C GY+ G T V I+ C C + C T G Y C C
Sbjct: 732 GTFRCECVEGYQFSDEG--TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSC 789
Query: 553 DVGFTRAADGRSC 565
GF + DG++C
Sbjct: 790 LPGF--SGDGQAC 800
Score = 74.1 bits (174), Expect = 1e-12
Identities = 47/129 (36%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCV------DVNECEIVDGV 170
+++EC+ P +CG H C N G F C+C GY+ S TCV +N CE
Sbjct: 710 DIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQ-FSDEGTCVAVVDQRPINYCETGLHN 768
Query: 171 CG---DGDCHNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSF 225
C C T G S+TC C PG+ D + C D+DEC + C C NT GSF
Sbjct: 769 CDIPQRAQCIYTGGSSYTCSCLPGFSGD--GQACQDVDEC--QPSRCHPDAFCYNTPGSF 824
Query: 226 RCECGHGME 234
C+C G +
Sbjct: 825 TCQCKPGYQ 833
Score = 66.5 bits (155), Expect = 2e-10
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 18/154 (11%)
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGMELAPDRLS 241
FTC C G++ D + C DIDEC++ ++C C N G+FRCEC G + + +
Sbjct: 693 FTCECSIGFRGD--GRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTC 750
Query: 242 CKDIDECSITSGICSNGA--CENQMGTYQCVCDEGYAQS-TVKSHXXXXXXXXXXXXRCQ 298
+D+ I C G C+ QC+ G + + + CQ
Sbjct: 751 VAVVDQRPIN--YCETGLHNCDIPQRA-QCIYTGGSSYTCSCLPGFSGDGQACQDVDECQ 807
Query: 299 HS-------CVNTPGSYHCTCREGWHLRADGRSC 325
S C NTPGS+ C C+ G+ + DG C
Sbjct: 808 PSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRC 839
Score = 62.5 bits (145), Expect = 4e-09
Identities = 27/66 (40%), Positives = 40/66 (60%), Gaps = 5/66 (7%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGDCHNTEGSFTCHCRPGYKADDFSKI 199
+TC C PG+ D + C DV+EC+ C D C+NT GSFTC C+PGY+ D F +
Sbjct: 785 YTCSCLPGFSGDGQ--ACQDVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV 840
Query: 200 CVDIDE 205
++++
Sbjct: 841 PGEVEK 846
Score = 61.7 bits (143), Expect = 7e-09
Identities = 58/201 (28%), Positives = 76/201 (37%), Gaps = 42/201 (20%)
Query: 234 ELAPDRLSCKDIDECSI-TSGICSNGACENQMGT-YQCVCDEGYAQSTVKSHXXXXXXXX 291
E +PD L + C I T G +N AC T + C C G+ +
Sbjct: 662 EGSPDALQ----NPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQ 717
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDE-----CAGGARPCG---GGQC 343
C N PG++ C C EG+ +G +D+ C G C QC
Sbjct: 718 PSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQC 777
Query: 344 RNTVGS-YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
T GS YTC+C +P +G CQD+DEC P C
Sbjct: 778 IYTGGSSYTCSC----LPGFSGDGQACQDVDECQ----------------------PSRC 811
Query: 403 GAGS-CHNTIGSFVCQCPDGY 422
+ C+NT GSF CQC GY
Sbjct: 812 HPDAFCYNTPGSFTCQCKPGY 832
Score = 32.7 bits (71), Expect = 3.6
Identities = 16/36 (44%), Positives = 19/36 (52%), Gaps = 3/36 (8%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD 152
+V+EC P C C N G FTC C PGY+ D
Sbjct: 802 DVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGD 835
>AJ224741-1|CAA12110.1| 486|Homo sapiens matrilin-3 protein.
Length = 486
Score = 105 bits (251), Expect = 6e-22
Identities = 56/187 (29%), Positives = 82/187 (43%), Gaps = 3/187 (1%)
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
F + +D C C+ + G CEC G L D+ +C +D C++ + C
Sbjct: 258 FQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGC 317
Query: 256 SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVN-TPGSYHCTCRE 314
+ ++ G+Y C C EGY + + CQH CVN GS+HC C E
Sbjct: 318 EHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYE 377
Query: 315 GWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDE 374
G+ L AD ++C D+CA G+ C + SY C C G + K TC +E
Sbjct: 378 GYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNE--DKKTCSATEE 435
Query: 375 CADLIST 381
L+ST
Sbjct: 436 ARRLVST 442
Score = 98.7 bits (235), Expect = 5e-20
Identities = 51/153 (33%), Positives = 71/153 (46%), Gaps = 3/153 (1%)
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNT-AGSFRCECGHGMELAPD 238
EG C C GY + K C +D CA N C CVN +GS+ CEC G L D
Sbjct: 284 EGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-ICVNDRSGSYHCECYEGYTLNED 342
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
R +C D+C++ + C + ++ G++ C C EGY + K CQ
Sbjct: 343 RKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQ 402
Query: 299 HSCVNT-PGSYHCTCREGWHLRADGRSCRDIDE 330
H CV+ SYHC C G+ L D ++C +E
Sbjct: 403 HICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
Score = 82.2 bits (194), Expect = 4e-15
Identities = 47/160 (29%), Positives = 73/160 (45%), Gaps = 7/160 (4%)
Query: 122 CAAFPGLCGHGRCRNLL-----GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
CA P + G +C+++ G C+C GY ++ TC ++ C + C
Sbjct: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVN-TAGSFRCECGHGMEL 235
++ GS+ C C GY ++ K C D+CA C+ CVN GS CEC G L
Sbjct: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQ-HICVNDRTGSHHCECYEGYTL 381
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
D+ +C D+C++ S C + + +Y C C GY
Sbjct: 382 NADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGY 421
Score = 71.7 bits (168), Expect = 6e-12
Identities = 48/158 (30%), Positives = 69/158 (43%), Gaps = 16/158 (10%)
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCIN-LPGSFQCRCRDGW--RG 468
G C+C GY++ ++ C+ D C L T C C+N GS+ C C +G+
Sbjct: 285 GKHHCECSQGYTLNADK-KTCSALDRCALNTHGCEHI--CVNDRSGSYHCECYEGYTLNE 341
Query: 469 DGATCEDVDECLTNNGGCHPRATCANT-DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
D TC D+C GC + C N GS C C GY + + C V D
Sbjct: 342 DRKTCSAQDKCALGTHGC--QHICVNDRTGSHHCECYEGYTLNAD--KKTCSVR-----D 392
Query: 528 ECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+CA C++ S+ Y CDC G+T D ++C
Sbjct: 393 KCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
Score = 63.3 bits (147), Expect = 2e-09
Identities = 34/129 (26%), Positives = 55/129 (42%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
++ CA C H + G + C+C+ GY + TC ++C + C ++
Sbjct: 307 LDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVND 366
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
GS C C GY + K C D+CA C+ + A S+ C+C G L D
Sbjct: 367 RTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNED 426
Query: 239 RLSCKDIDE 247
+ +C +E
Sbjct: 427 KKTCSATEE 435
Score = 60.9 bits (141), Expect = 1e-08
Identities = 42/134 (31%), Positives = 57/134 (42%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINL-PGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATC 492
D C LGT C CI+ G C C G+ D TC +D C N GC C
Sbjct: 266 DPCVLGTHQCQHV--CISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH--IC 321
Query: 493 ANT-DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
N GS+ C C GY + R C D+CA C++ ++ G + C+
Sbjct: 322 VNDRSGSYHCECYEGYTLNED--RKTCSAQ-----DKCALGTHGCQHICVNDRTGSHHCE 374
Query: 552 CDVGFTRAADGRSC 565
C G+T AD ++C
Sbjct: 375 CYEGYTLNADKKTC 388
Score = 38.7 bits (86), Expect = 0.054
Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
+D C+ C ++ +G C C GY + +T C +D CA +
Sbjct: 265 LDPCVLGTHQCQ-HVCISDGEGKHHCECSQGYTLNA-DKKT------CSALDRCALNTHG 316
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
CE+ ++ G Y C+C G+T D ++C
Sbjct: 317 CEHICVNDRSGSYHCECYEGYTLNEDRKTC 346
>AJ001047-1|CAA04501.1| 303|Homo sapiens Matrilin-3 protein.
Length = 303
Score = 105 bits (251), Expect = 6e-22
Identities = 56/187 (29%), Positives = 82/187 (43%), Gaps = 3/187 (1%)
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
F + +D C C+ + G CEC G L D+ +C +D C++ + C
Sbjct: 75 FQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGC 134
Query: 256 SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVN-TPGSYHCTCRE 314
+ ++ G+Y C C EGY + + CQH CVN GS+HC C E
Sbjct: 135 EHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYE 194
Query: 315 GWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDE 374
G+ L AD ++C D+CA G+ C + SY C C G + K TC +E
Sbjct: 195 GYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNE--DKKTCSATEE 252
Query: 375 CADLIST 381
L+ST
Sbjct: 253 ARRLVST 259
Score = 98.7 bits (235), Expect = 5e-20
Identities = 51/153 (33%), Positives = 71/153 (46%), Gaps = 3/153 (1%)
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNT-AGSFRCECGHGMELAPD 238
EG C C GY + K C +D CA N C CVN +GS+ CEC G L D
Sbjct: 101 EGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-ICVNDRSGSYHCECYEGYTLNED 159
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
R +C D+C++ + C + ++ G++ C C EGY + K CQ
Sbjct: 160 RKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQ 219
Query: 299 HSCVNT-PGSYHCTCREGWHLRADGRSCRDIDE 330
H CV+ SYHC C G+ L D ++C +E
Sbjct: 220 HICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 252
Score = 82.2 bits (194), Expect = 4e-15
Identities = 47/160 (29%), Positives = 73/160 (45%), Gaps = 7/160 (4%)
Query: 122 CAAFPGLCGHGRCRNLL-----GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
CA P + G +C+++ G C+C GY ++ TC ++ C + C
Sbjct: 80 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 139
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVN-TAGSFRCECGHGMEL 235
++ GS+ C C GY ++ K C D+CA C+ CVN GS CEC G L
Sbjct: 140 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQ-HICVNDRTGSHHCECYEGYTL 198
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
D+ +C D+C++ S C + + +Y C C GY
Sbjct: 199 NADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGY 238
Score = 71.7 bits (168), Expect = 6e-12
Identities = 48/158 (30%), Positives = 69/158 (43%), Gaps = 16/158 (10%)
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCIN-LPGSFQCRCRDGW--RG 468
G C+C GY++ ++ C+ D C L T C C+N GS+ C C +G+
Sbjct: 102 GKHHCECSQGYTLNADK-KTCSALDRCALNTHGCEHI--CVNDRSGSYHCECYEGYTLNE 158
Query: 469 DGATCEDVDECLTNNGGCHPRATCANT-DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
D TC D+C GC + C N GS C C GY + + C V D
Sbjct: 159 DRKTCSAQDKCALGTHGC--QHICVNDRTGSHHCECYEGYTLNAD--KKTCSVR-----D 209
Query: 528 ECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+CA C++ S+ Y CDC G+T D ++C
Sbjct: 210 KCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 247
Score = 63.3 bits (147), Expect = 2e-09
Identities = 34/129 (26%), Positives = 55/129 (42%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
++ CA C H + G + C+C+ GY + TC ++C + C ++
Sbjct: 124 LDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVND 183
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
GS C C GY + K C D+CA C+ + A S+ C+C G L D
Sbjct: 184 RTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNED 243
Query: 239 RLSCKDIDE 247
+ +C +E
Sbjct: 244 KKTCSATEE 252
Score = 60.9 bits (141), Expect = 1e-08
Identities = 42/134 (31%), Positives = 57/134 (42%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINL-PGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATC 492
D C LGT C CI+ G C C G+ D TC +D C N GC C
Sbjct: 83 DPCVLGTHQCQHV--CISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH--IC 138
Query: 493 ANT-DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
N GS+ C C GY + R C D+CA C++ ++ G + C+
Sbjct: 139 VNDRSGSYHCECYEGYTLNED--RKTCSAQ-----DKCALGTHGCQHICVNDRTGSHHCE 191
Query: 552 CDVGFTRAADGRSC 565
C G+T AD ++C
Sbjct: 192 CYEGYTLNADKKTC 205
Score = 38.7 bits (86), Expect = 0.054
Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
+D C+ C ++ +G C C GY + +T C +D CA +
Sbjct: 82 LDPCVLGTHQCQ-HVCISDGEGKHHCECSQGYTLNA-DKKT------CSALDRCALNTHG 133
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
CE+ ++ G Y C+C G+T D ++C
Sbjct: 134 CEHICVNDRSGSYHCECYEGYTLNEDRKTC 163
>AC079145-2|AAX88937.1| 486|Homo sapiens unknown protein.
Length = 486
Score = 105 bits (251), Expect = 6e-22
Identities = 56/187 (29%), Positives = 82/187 (43%), Gaps = 3/187 (1%)
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
F + +D C C+ + G CEC G L D+ +C +D C++ + C
Sbjct: 258 FQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGC 317
Query: 256 SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVN-TPGSYHCTCRE 314
+ ++ G+Y C C EGY + + CQH CVN GS+HC C E
Sbjct: 318 EHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYE 377
Query: 315 GWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDE 374
G+ L AD ++C D+CA G+ C + SY C C G + K TC +E
Sbjct: 378 GYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNE--DKKTCSATEE 435
Query: 375 CADLIST 381
L+ST
Sbjct: 436 ARRLVST 442
Score = 98.7 bits (235), Expect = 5e-20
Identities = 51/153 (33%), Positives = 71/153 (46%), Gaps = 3/153 (1%)
Query: 180 EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNT-AGSFRCECGHGMELAPD 238
EG C C GY + K C +D CA N C CVN +GS+ CEC G L D
Sbjct: 284 EGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-ICVNDRSGSYHCECYEGYTLNED 342
Query: 239 RLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
R +C D+C++ + C + ++ G++ C C EGY + K CQ
Sbjct: 343 RKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQ 402
Query: 299 HSCVNT-PGSYHCTCREGWHLRADGRSCRDIDE 330
H CV+ SYHC C G+ L D ++C +E
Sbjct: 403 HICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
Score = 82.2 bits (194), Expect = 4e-15
Identities = 47/160 (29%), Positives = 73/160 (45%), Gaps = 7/160 (4%)
Query: 122 CAAFPGLCGHGRCRNLL-----GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDC 176
CA P + G +C+++ G C+C GY ++ TC ++ C + C
Sbjct: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
Query: 177 HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVN-TAGSFRCECGHGMEL 235
++ GS+ C C GY ++ K C D+CA C+ CVN GS CEC G L
Sbjct: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQ-HICVNDRTGSHHCECYEGYTL 381
Query: 236 APDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
D+ +C D+C++ S C + + +Y C C GY
Sbjct: 382 NADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGY 421
Score = 71.7 bits (168), Expect = 6e-12
Identities = 48/158 (30%), Positives = 69/158 (43%), Gaps = 16/158 (10%)
Query: 412 GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCIN-LPGSFQCRCRDGW--RG 468
G C+C GY++ ++ C+ D C L T C C+N GS+ C C +G+
Sbjct: 285 GKHHCECSQGYTLNADK-KTCSALDRCALNTHGCEHI--CVNDRSGSYHCECYEGYTLNE 341
Query: 469 DGATCEDVDECLTNNGGCHPRATCANT-DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDID 527
D TC D+C GC + C N GS C C GY + + C V D
Sbjct: 342 DRKTCSAQDKCALGTHGC--QHICVNDRTGSHHCECYEGYTLNAD--KKTCSVR-----D 392
Query: 528 ECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSC 565
+CA C++ S+ Y CDC G+T D ++C
Sbjct: 393 KCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
Score = 63.3 bits (147), Expect = 2e-09
Identities = 34/129 (26%), Positives = 55/129 (42%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHN 178
++ CA C H + G + C+C+ GY + TC ++C + C ++
Sbjct: 307 LDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVND 366
Query: 179 TEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
GS C C GY + K C D+CA C+ + A S+ C+C G L D
Sbjct: 367 RTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNED 426
Query: 239 RLSCKDIDE 247
+ +C +E
Sbjct: 427 KKTCSATEE 435
Score = 60.9 bits (141), Expect = 1e-08
Identities = 42/134 (31%), Positives = 57/134 (42%), Gaps = 15/134 (11%)
Query: 436 DECELGTCDCHPAADCINL-PGSFQCRCRDGW--RGDGATCEDVDECLTNNGGCHPRATC 492
D C LGT C CI+ G C C G+ D TC +D C N GC C
Sbjct: 266 DPCVLGTHQCQHV--CISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH--IC 321
Query: 493 ANT-DGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECD 551
N GS+ C C GY + R C D+CA C++ ++ G + C+
Sbjct: 322 VNDRSGSYHCECYEGYTLNED--RKTCSAQ-----DKCALGTHGCQHICVNDRTGSHHCE 374
Query: 552 CDVGFTRAADGRSC 565
C G+T AD ++C
Sbjct: 375 CYEGYTLNADKKTC 388
Score = 38.7 bits (86), Expect = 0.054
Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
+D C+ C ++ +G C C GY + +T C +D CA +
Sbjct: 265 LDPCVLGTHQCQ-HVCISDGEGKHHCECSQGYTLNA-DKKT------CSALDRCALNTHG 316
Query: 536 CENGHCSNTPGGYECDCDVGFTRAADGRSC 565
CE+ ++ G Y C+C G+T D ++C
Sbjct: 317 CEHICVNDRSGSYHCECYEGYTLNEDRKTC 346
>AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) variant
protein.
Length = 1241
Score = 104 bits (250), Expect = 7e-22
Identities = 64/171 (37%), Positives = 81/171 (47%), Gaps = 34/171 (19%)
Query: 350 YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CH 408
+TC C+ G G TC DIDEC++ P +CG+ + C+
Sbjct: 692 FTCECSIGF----RGDGRTCYDIDECSEQ--------------------PSVCGSHTICN 727
Query: 409 NTIGSFVCQCPDGYSVKPEQGPACTDDDE----CELG--TCDCHPAADCINLPGS-FQCR 461
N G+F C+C +GY E D CE G CD A CI GS + C
Sbjct: 728 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 787
Query: 462 CRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
C G+ GDG C+DVDEC + CHP A C NT GSF C C GY+GDG+
Sbjct: 788 CLPGFSGDGQACQDVDECHPSR--CHPDAFCYNTPGSFTCQCKPGYQGDGF 836
Score = 93.1 bits (221), Expect = 2e-18
Identities = 62/183 (33%), Positives = 85/183 (46%), Gaps = 28/183 (15%)
Query: 297 CQHSCVNTPG---SYHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTC 352
C + PG + C C G+ R DGR+C DIDEC+ CG C N G++ C
Sbjct: 678 CDTNAACRPGPRTQFTCECSIGF--RGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRC 735
Query: 353 TCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSV-DPQIPELCGAGSCHNTI 411
C +G S G TC ++ + ++ + + + IP+ C T
Sbjct: 736 ECVEGYQFSDEG---TC---------VAVVDQRPINYCETGLHNCDIPQ---RAQCIYTG 780
Query: 412 GS-FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDG 470
GS + C C G+S G AC D DEC C HP A C N PGSF C+C+ G++GDG
Sbjct: 781 GSSYTCSCLPGFS---GDGQACQDVDECHPSRC--HPDAFCYNTPGSFTCQCKPGYQGDG 835
Query: 471 ATC 473
C
Sbjct: 836 FRC 838
Score = 83.8 bits (198), Expect = 1e-15
Identities = 55/164 (33%), Positives = 73/164 (44%), Gaps = 27/164 (16%)
Query: 414 FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWR-GDGAT 472
F C+C G+ G C D DEC C C N PG+F+C C +G++ D T
Sbjct: 692 FTCECSIGFR---GDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGT 748
Query: 473 C------EDVDECLTNNGGCH--PRATCANTDG-SFRCLCDTGYKGDGYGLRTVCCVYSC 523
C ++ C T C RA C T G S+ C C G+ GDG +C
Sbjct: 749 CVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDG---------QAC 799
Query: 524 VDIDECANDPTLCE-NGHCSNTPGGYECDCDVGFTRAADGRSCL 566
D+DEC P+ C + C NTPG + C C G+ DG C+
Sbjct: 800 QDVDEC--HPSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRCV 839
Score = 83.4 bits (197), Expect = 2e-15
Identities = 71/237 (29%), Positives = 96/237 (40%), Gaps = 28/237 (11%)
Query: 208 DNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC-SNGACENQMGT 266
D +A CR G F CEC G D +C DIDECS +C S+ C N GT
Sbjct: 679 DTNAACRPG----PRTQFTCECSIGFR--GDGRTCYDIDECSEQPSVCGSHTICNNHPGT 732
Query: 267 YQCVCDEGYAQSTVKSHXXXXXXX-----XXXXXRC----QHSCVNTPGS-YHCTCREGW 316
++C C EGY S + C + C+ T GS Y C+C G+
Sbjct: 733 FRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF 792
Query: 317 HLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECA 376
DG++C+D+DEC +R C NT GS+TC C G P + C
Sbjct: 793 S--GDGQACQDVDECHP-SRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQ 849
Query: 377 DLISTII-MMSVDELQKSVDPQ--IPELCGAG-----SCHNTIGSFVCQCPDGYSVK 425
I+ + Q+ + P +PE G CH + G C DG V+
Sbjct: 850 HEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVE 906
Score = 79.4 bits (187), Expect = 3e-14
Identities = 47/145 (32%), Positives = 69/145 (47%), Gaps = 15/145 (10%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD-CHNTEGSFTCHCRPGYKADDFSKI 199
FTC+C G+ D + TC D++EC VCG C+N G+F C C GY+ D
Sbjct: 692 FTCECSIGFRGDGR--TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTC 749
Query: 200 CVDIDE-----C---ADNDALCRGGRCVNTAG-SFRCECGHGMELAPDRLSCKDIDECSI 250
+D+ C N + + +C+ T G S+ C C G + D +C+D+DEC
Sbjct: 750 VAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPG--FSGDGQACQDVDECH- 806
Query: 251 TSGICSNGACENQMGTYQCVCDEGY 275
S + C N G++ C C GY
Sbjct: 807 PSRCHPDAFCYNTPGSFTCQCKPGY 831
Score = 78.6 bits (185), Expect = 5e-14
Identities = 48/133 (36%), Positives = 59/133 (44%), Gaps = 9/133 (6%)
Query: 438 CELGTCDCHPAADCINLPGS-FQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTD 496
C +GT C A C P + F C C G+RGDG TC D+DEC C C N
Sbjct: 671 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHP 730
Query: 497 GSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLC---ENGHCSNTPG-GYECDC 552
G+FRC C GY+ G T V I+ C C + C T G Y C C
Sbjct: 731 GTFRCECVEGYQFSDEG--TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSC 788
Query: 553 DVGFTRAADGRSC 565
GF + DG++C
Sbjct: 789 LPGF--SGDGQAC 799
Score = 74.5 bits (175), Expect = 9e-13
Identities = 47/129 (36%), Positives = 63/129 (48%), Gaps = 17/129 (13%)
Query: 118 EVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCV------DVNECEIVDGV 170
+++EC+ P +CG H C N G F C+C GY+ S TCV +N CE
Sbjct: 709 DIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQ-FSDEGTCVAVVDQRPINYCETGLHN 767
Query: 171 CG---DGDCHNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSF 225
C C T G S+TC C PG+ D + C D+DEC + + C C NT GSF
Sbjct: 768 CDIPQRAQCIYTGGSSYTCSCLPGFSGD--GQACQDVDEC--HPSRCHPDAFCYNTPGSF 823
Query: 226 RCECGHGME 234
C+C G +
Sbjct: 824 TCQCKPGYQ 832
Score = 66.5 bits (155), Expect = 2e-10
Identities = 46/154 (29%), Positives = 66/154 (42%), Gaps = 18/154 (11%)
Query: 183 FTCHCRPGYKADDFSKICVDIDECADNDALCRGGR-CVNTAGSFRCECGHGMELAPDRLS 241
FTC C G++ D + C DIDEC++ ++C C N G+FRCEC G + + +
Sbjct: 692 FTCECSIGFRGD--GRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTC 749
Query: 242 CKDIDECSITSGICSNGA--CENQMGTYQCVCDEG--YAQSTVKSHXXXXXXXXXXX--- 294
+D+ I C G C+ QC+ G Y S +
Sbjct: 750 VAVVDQRPIN--YCETGLHNCDIPQRA-QCIYTGGSSYTCSCLPGFSGDGQACQDVDECH 806
Query: 295 -XRCQHS--CVNTPGSYHCTCREGWHLRADGRSC 325
RC C NTPGS+ C C+ G+ + DG C
Sbjct: 807 PSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRC 838
Score = 61.7 bits (143), Expect = 7e-09
Identities = 27/66 (40%), Positives = 39/66 (59%), Gaps = 5/66 (7%)
Query: 141 FTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGDCHNTEGSFTCHCRPGYKADDFSKI 199
+TC C PG+ D + C DV+EC C D C+NT GSFTC C+PGY+ D F +
Sbjct: 784 YTCSCLPGFSGDGQ--ACQDVDECH--PSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV 839
Query: 200 CVDIDE 205
++++
Sbjct: 840 PGEVEK 845
Score = 61.3 bits (142), Expect = 9e-09
Identities = 58/201 (28%), Positives = 76/201 (37%), Gaps = 42/201 (20%)
Query: 234 ELAPDRLSCKDIDECSI-TSGICSNGACENQMGT-YQCVCDEGYAQSTVKSHXXXXXXXX 291
E +PD L + C I T G +N AC T + C C G+ +
Sbjct: 661 EGSPDALQ----NPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQ 716
Query: 292 XXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRDIDE-----CAGGARPCG---GGQC 343
C N PG++ C C EG+ +G +D+ C G C QC
Sbjct: 717 PSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQC 776
Query: 344 RNTVGS-YTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELC 402
T GS YTC+C +P +G CQD+DEC P C
Sbjct: 777 IYTGGSSYTCSC----LPGFSGDGQACQDVDECH----------------------PSRC 810
Query: 403 GAGS-CHNTIGSFVCQCPDGY 422
+ C+NT GSF CQC GY
Sbjct: 811 HPDAFCYNTPGSFTCQCKPGY 831
Score = 32.7 bits (71), Expect = 3.6
Identities = 16/36 (44%), Positives = 19/36 (52%), Gaps = 3/36 (8%)
Query: 118 EVNECAAFPGLCGHGR-CRNLLGGFTCDCFPGYEKD 152
+V+EC P C C N G FTC C PGY+ D
Sbjct: 801 DVDEC--HPSRCHPDAFCYNTPGSFTCQCKPGYQGD 834
>AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein.
Length = 969
Score = 103 bits (246), Expect = 2e-21
Identities = 49/117 (41%), Positives = 64/117 (54%), Gaps = 5/117 (4%)
Query: 119 VNECAA-FPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCH 177
++ CAA +CG G C NL G+ C C PGY+ C D NEC + D G G C
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNEC-LRDPCKGKGRCI 903
Query: 178 NTEGSFTCHCRPGY--KADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHG 232
N GS++C C PGY ++ C DI+EC + +C GG+C NT GS+ CEC G
Sbjct: 904 NRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQG 959
Score = 89.8 bits (213), Expect = 2e-17
Identities = 45/129 (34%), Positives = 60/129 (46%), Gaps = 10/129 (7%)
Query: 436 DECELGTCDCHPAADCINLPGSFQCRCRDGWR--GDGATCEDVDECLTNNGGCHPRATCA 493
D C G + C+NLP ++C C G++ A C D +ECL + C + C
Sbjct: 846 DRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CKGKGRCI 903
Query: 494 NTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCD 553
N GS+ C C GY L T C DI+EC P +C G C+NT G Y C+CD
Sbjct: 904 NRVGSYSCFCYPGYT-----LATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECD 957
Query: 554 VGFTRAADG 562
G+ G
Sbjct: 958 QGYIMVRKG 966
Score = 85.8 bits (203), Expect = 4e-16
Identities = 43/123 (34%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
Query: 240 LSCKDIDECSI-TSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
LS ID C+ + +C G C N Y+CVC GY +++ + +
Sbjct: 840 LSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGK 899
Query: 299 HSCVNTPGSYHCTCREGWHLRADG--RSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTD 356
C+N GSY C C G+ L G + C+DI+EC C GGQC NT GSY C C
Sbjct: 900 GRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPG-VCSGGQCTNTEGSYHCECDQ 958
Query: 357 GLV 359
G +
Sbjct: 959 GYI 961
Score = 85.0 bits (201), Expect = 6e-16
Identities = 46/124 (37%), Positives = 58/124 (46%), Gaps = 24/124 (19%)
Query: 300 SCVNTPGSYHCTCREGWHLRADGRSCRDIDECAGGARPCGG-GQCRNTVGSYTCTCTDGL 358
+CVN P Y C C G+ L C D +EC PC G G+C N VGSY+C C G
Sbjct: 860 TCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRD--PCKGKGRCINRVGSYSCFCYPGY 917
Query: 359 VPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTIGSFVCQC 418
+ +GA CQDI+EC + P +C G C NT GS+ C+C
Sbjct: 918 TLATSGATQECQDINEC---------------------EQPGVCSGGQCTNTEGSYHCEC 956
Query: 419 PDGY 422
GY
Sbjct: 957 DQGY 960
Score = 84.2 bits (199), Expect = 1e-15
Identities = 44/111 (39%), Positives = 56/111 (50%), Gaps = 9/111 (8%)
Query: 401 LCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQC 460
+CG G+C N + C C GY + P Q CTDD+EC C CIN GS+ C
Sbjct: 855 VCGPGTCVNLPDGYRCVCSPGYQLHPSQA-YCTDDNECLRD--PCKGKGRCINRVGSYSC 911
Query: 461 RCRDGW--RGDGAT--CEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGY 507
C G+ GAT C+D++EC G C NT+GS+ C CD GY
Sbjct: 912 FCYPGYTLATSGATQECQDINEC--EQPGVCSGGQCTNTEGSYHCECDQGY 960
Score = 77.0 bits (181), Expect = 2e-13
Identities = 37/75 (49%), Positives = 44/75 (58%), Gaps = 6/75 (8%)
Query: 120 NECAAFPGLC-GHGRCRNLLGGFTCDCFPGYEKDSKNHT--CVDVNECEIVDGVCGDGDC 176
NEC P C G GRC N +G ++C C+PGY + T C D+NECE GVC G C
Sbjct: 889 NECLRDP--CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQC 945
Query: 177 HNTEGSFTCHCRPGY 191
NTEGS+ C C GY
Sbjct: 946 TNTEGSYHCECDQGY 960
Score = 75.8 bits (178), Expect = 4e-13
Identities = 40/117 (34%), Positives = 53/117 (45%), Gaps = 4/117 (3%)
Query: 203 IDECADNDA-LCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGACE 261
ID CA +C G CVN +RC C G +L P + C D +EC + G C
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNEC-LRDPCKGKGRCI 903
Query: 262 NQMGTYQCVCDEGYAQSTV-KSHXXXXXXXXXXXXRCQ-HSCVNTPGSYHCTCREGW 316
N++G+Y C C GY +T + C C NT GSYHC C +G+
Sbjct: 904 NRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGY 960
Score = 59.7 bits (138), Expect = 3e-08
Identities = 22/47 (46%), Positives = 33/47 (70%), Gaps = 1/47 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKKGTDAYQNLCIA 50
G C+ PL + + +CCCS +GKAWG++ CE CP GT+A++ +C A
Sbjct: 681 GTCTLPLAQRITKQICCCSRVGKAWGSE-CEKCPLPGTEAFREICPA 726
Score = 57.6 bits (133), Expect = 1e-07
Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Query: 144 DCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDI 203
+C GY++ + H C D+NEC + G+C D +C NT GS+ C CRPG D CV
Sbjct: 607 ECPQGYKRLNLTH-CQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD 664
Query: 204 DECADNDALC 213
+ LC
Sbjct: 665 KAISMLQGLC 674
Score = 54.4 bits (125), Expect = 1e-06
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 187 CRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDID 246
C GYK + + C DI+EC LC+ CVNT GS+ C C G+ L P R C
Sbjct: 608 CPQGYKRLNLTH-CQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDK 665
Query: 247 ECSITSGIC 255
S+ G+C
Sbjct: 666 AISMLQGLC 674
Score = 50.0 bits (114), Expect = 2e-05
Identities = 31/89 (34%), Positives = 38/89 (42%), Gaps = 12/89 (13%)
Query: 476 VDECLTN-NGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
+D C C P TC N +RC+C GY+ L C D +EC DP
Sbjct: 845 IDRCAAGATNVCGP-GTCVNLPDGYRCVCSPGYQ-----LHPSQAY--CTDDNECLRDP- 895
Query: 535 LCE-NGHCSNTPGGYECDCDVGFTRAADG 562
C+ G C N G Y C C G+T A G
Sbjct: 896 -CKGKGRCINRVGSYSCFCYPGYTLATSG 923
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVC----GD 173
++NEC GLC C N G + C C PG D CV ++ G+C G
Sbjct: 622 DINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGP 680
Query: 174 GDC 176
G C
Sbjct: 681 GTC 683
Score = 40.7 bits (91), Expect = 0.013
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEG 274
EC G + + C+DI+EC +T G+C + C N G+Y C C G
Sbjct: 607 ECPQGYKRL-NLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPG 651
Score = 40.7 bits (91), Expect = 0.013
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 118 EVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNH 156
++NEC PG+C G+C N G + C+C GY K H
Sbjct: 930 DINECEQ-PGVCSGGQCTNTEGSYHCECDQGYIMVRKGH 967
Score = 40.3 bits (90), Expect = 0.018
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 6/65 (9%)
Query: 443 CDCHPAADCINLPGSFQCRCRDGWRGDGAT-CEDVDECLTNNGGCHPRATCANTDGSFRC 501
C PA+ I + Q C G++ T C+D++ECLT G C A C NT GS+ C
Sbjct: 592 CPPRPASPVIE---NGQLECPQGYKRLNLTHCQDINECLTL-GLCKD-AECVNTRGSYLC 646
Query: 502 LCDTG 506
C G
Sbjct: 647 TCRPG 651
Score = 39.9 bits (89), Expect = 0.024
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Query: 312 CREGWHLRADGRSCRDIDECAGGARPCGGGQCRNTVGSYTCTCTDGLV 359
C +G+ R + C+DI+EC C +C NT GSY CTC GL+
Sbjct: 608 CPQGYK-RLNLTHCQDINECLTLGL-CKDAECVNTRGSYLCTCRPGLM 653
Score = 37.9 bits (84), Expect = 0.095
Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 6/50 (12%)
Query: 417 QCPDGYSVKPEQGPACTDDDEC-ELGTCDCHPAADCINLPGSFQCRCRDG 465
+CP GY K C D +EC LG C A+C+N GS+ C CR G
Sbjct: 607 ECPQGY--KRLNLTHCQDINECLTLGLCK---DAECVNTRGSYLCTCRPG 651
Score = 35.9 bits (79), Expect = 0.38
Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 6/86 (6%)
Query: 268 QCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREGWHLRADGRSCRD 327
Q C +GY + + +H CVNT GSY CTCR G L D R
Sbjct: 605 QLECPQGYKRLNL-THCQDINECLTLGLCKDAECVNTRGSYLCTCRPG--LMLDPSRSRC 661
Query: 328 IDECAGGARPCGGGQCRNTVGSYTCT 353
+ + A G C ++G TCT
Sbjct: 662 VSDKAISMLQ---GLCYRSLGPGTCT 684
Score = 35.1 bits (77), Expect = 0.67
Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 4 GRCSGPLPTDVLRAVCCCSALGKAWGNQRCEPCPKK 39
G+C+ PL ++ CC ++G WG C PCP +
Sbjct: 561 GQCANPL-LELTTQEDCCGSVGAFWGVTLCAPCPPR 595
Score = 34.3 bits (75), Expect = 1.2
Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 523 CVDIDECANDPTLCENGHCSNTPGGYECDCDVG 555
C DI+EC LC++ C NT G Y C C G
Sbjct: 620 CQDINECLT-LGLCKDAECVNTRGSYLCTCRPG 651
>D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein.
Length = 1376
Score = 101 bits (241), Expect = 9e-21
Identities = 53/118 (44%), Positives = 63/118 (53%), Gaps = 9/118 (7%)
Query: 402 CGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACT---DDDECELGTCDCHPA--ADCINLP 455
CG S C N GS+ C+C GY ++ + CE G+ C PA A C++
Sbjct: 813 CGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHG 872
Query: 456 GS-FQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
GS F C C G+ GDG C DVDEC N CHP ATC NT GSF C C GY GDG+
Sbjct: 873 GSTFSCACLPGYAGDGHQCTDVDECSENR--CHPAATCYNTPGSFSCRCQPGYYGDGF 928
Score = 100 bits (240), Expect = 1e-20
Identities = 61/171 (35%), Positives = 80/171 (46%), Gaps = 27/171 (15%)
Query: 407 CHNTIG-SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
CH G + C+C GY G C D++EC G C P + CINLPGS++C CR G
Sbjct: 777 CHPGTGVDYTCECASGYQ---GDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSG 833
Query: 466 WR--GDGATC----EDVDECLTNNGGCHP--RATCANTDGS-FRCLCDTGYKGDGYGLRT 516
+ D TC + C + C P +A C + GS F C C GY GDG+
Sbjct: 834 YEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGH---- 889
Query: 517 VCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTRAADGRSCL 566
C D+DEC+ + C C NTPG + C C G+ DG C+
Sbjct: 890 -----QCTDVDECSENR--CHPAATCYNTPGSFSCRCQPGY--YGDGFQCI 931
Score = 96.7 bits (230), Expect = 2e-19
Identities = 62/168 (36%), Positives = 75/168 (44%), Gaps = 24/168 (14%)
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAK 366
Y C C G+ + DGR+C D +ECA G CG C N GSY C C G A +
Sbjct: 785 YTCECASGY--QGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGY--EFADDR 840
Query: 367 PTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC-HNTIGSFVCQCPDGYSVK 425
TC +I + + P G C H+ +F C C GY+
Sbjct: 841 HTC-----------ILITPPANPCEDGSHTCAP--AGQARCVHHGGSTFSCACLPGYA-- 885
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC 473
G CTD DEC C HPAA C N PGSF CRC+ G+ GDG C
Sbjct: 886 -GDGHQCTDVDECSENRC--HPAATCYNTPGSFSCRCQPGYYGDGFQC 930
Score = 93.1 bits (221), Expect = 2e-18
Identities = 63/169 (37%), Positives = 76/169 (44%), Gaps = 18/169 (10%)
Query: 119 VNECAAFPGLCGH-GRCRNLLG-GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
VN C +C RC G +TC+C GY+ D +N CVD NEC CG
Sbjct: 761 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRN--CVDENECATGFHRCGPNSV 818
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDI----DECADNDALCR---GGRCVNTAGS-FRC 227
C N GS+ C CR GY+ D C+ I + C D C RCV+ GS F C
Sbjct: 819 CINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSC 878
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
C G A D C D+DECS C A C N G++ C C GY
Sbjct: 879 ACLPG--YAGDGHQCTDVDECS--ENRCHPAATCYNTPGSFSCRCQPGY 923
Score = 87.0 bits (206), Expect = 2e-16
Identities = 63/191 (32%), Positives = 81/191 (42%), Gaps = 23/191 (12%)
Query: 161 VNECEIVDGVCGD-GDCHNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR- 217
VN C +C CH G +TC C GY+ D + CVD +ECA C
Sbjct: 761 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGD--GRNCVDENECATGFHRCGPNSV 818
Query: 218 CVNTAGSFRCECGHGMELAPDRLSC----KDIDECSITSGICS---NGACENQMG-TYQC 269
C+N GS+RCEC G E A DR +C + C S C+ C + G T+ C
Sbjct: 819 CINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSC 878
Query: 270 VCDEGYAQSTVKSHXXXXXXXXXXXXRCQ--HSCVNTPGSYHCTCREGWHLRADGRSCRD 327
C GYA H RC +C NTPGS+ C C+ G++ DG C
Sbjct: 879 ACLPGYAGD---GH-QCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYY--GDGFQC-- 930
Query: 328 IDECAGGARPC 338
I + PC
Sbjct: 931 IPDSTSSLTPC 941
Score = 85.8 bits (203), Expect = 4e-16
Identities = 52/140 (37%), Positives = 65/140 (46%), Gaps = 19/140 (13%)
Query: 117 MEVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCV----DVNECEIVDGVC 171
++ NECA CG + C NL G + C+C GYE HTC+ N CE C
Sbjct: 801 VDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTC 860
Query: 172 ---GDGDC-HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR 226
G C H+ +F+C C PGY D C D+DEC++N C C NT GSF
Sbjct: 861 APAGQARCVHHGGSTFSCACLPGYAGDGHQ--CTDVDECSEN--RCHPAATCYNTPGSFS 916
Query: 227 CEC-----GHGMELAPDRLS 241
C C G G + PD S
Sbjct: 917 CRCQPGYYGDGFQCIPDSTS 936
Score = 70.1 bits (164), Expect = 2e-11
Identities = 44/154 (28%), Positives = 63/154 (40%), Gaps = 15/154 (9%)
Query: 422 YSVKPEQGPACTDDDECELGTCD-----CHPAADCINLPG-SFQCRCRDGWRGDGATCED 475
++V + GP D D + C C A C G + C C G++GDG C D
Sbjct: 743 FAVTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVD 802
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
+EC T C P + C N GS+RC C +GY+ + C+ + C +
Sbjct: 803 ENECATGFHRCGPNSVCINLPGSYRCECRSGYE---FADDRHTCILITPPANPCEDGSHT 859
Query: 536 CE---NGHCSNTPGG-YECDCDVGFTRAADGRSC 565
C C + G + C C G+ A DG C
Sbjct: 860 CAPAGQARCVHHGGSTFSCACLPGY--AGDGHQC 891
Score = 56.8 bits (131), Expect = 2e-07
Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 11/93 (11%)
Query: 476 VDECLTNNGGCHPRATC-ANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
V+ C + C A C T + C C +GY+GDG +CVD +ECA
Sbjct: 761 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGR---------NCVDENECATGFH 811
Query: 535 LC-ENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C N C N PG Y C+C G+ A D +C+
Sbjct: 812 RCGPNSVCINLPGSYRCECRSGYEFADDRHTCI 844
>AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein.
Length = 1375
Score = 101 bits (241), Expect = 9e-21
Identities = 53/118 (44%), Positives = 63/118 (53%), Gaps = 9/118 (7%)
Query: 402 CGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACT---DDDECELGTCDCHPA--ADCINLP 455
CG S C N GS+ C+C GY ++ + CE G+ C PA A C++
Sbjct: 812 CGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHG 871
Query: 456 GS-FQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
GS F C C G+ GDG C DVDEC N CHP ATC NT GSF C C GY GDG+
Sbjct: 872 GSTFSCACLPGYAGDGHQCTDVDECSENR--CHPAATCYNTPGSFSCRCQPGYYGDGF 927
Score = 100 bits (240), Expect = 1e-20
Identities = 61/171 (35%), Positives = 80/171 (46%), Gaps = 27/171 (15%)
Query: 407 CHNTIG-SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
CH G + C+C GY G C D++EC G C P + CINLPGS++C CR G
Sbjct: 776 CHPGTGVDYTCECASGYQ---GDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSG 832
Query: 466 WR--GDGATC----EDVDECLTNNGGCHP--RATCANTDGS-FRCLCDTGYKGDGYGLRT 516
+ D TC + C + C P +A C + GS F C C GY GDG+
Sbjct: 833 YEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGH---- 888
Query: 517 VCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTRAADGRSCL 566
C D+DEC+ + C C NTPG + C C G+ DG C+
Sbjct: 889 -----QCTDVDECSENR--CHPAATCYNTPGSFSCRCQPGY--YGDGFQCI 930
Score = 96.7 bits (230), Expect = 2e-19
Identities = 62/168 (36%), Positives = 75/168 (44%), Gaps = 24/168 (14%)
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAK 366
Y C C G+ + DGR+C D +ECA G CG C N GSY C C G A +
Sbjct: 784 YTCECASGY--QGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGY--EFADDR 839
Query: 367 PTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC-HNTIGSFVCQCPDGYSVK 425
TC +I + + P G C H+ +F C C GY+
Sbjct: 840 HTC-----------ILITPPANPCEDGSHTCAP--AGQARCVHHGGSTFSCACLPGYA-- 884
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC 473
G CTD DEC C HPAA C N PGSF CRC+ G+ GDG C
Sbjct: 885 -GDGHQCTDVDECSENRC--HPAATCYNTPGSFSCRCQPGYYGDGFQC 929
Score = 93.1 bits (221), Expect = 2e-18
Identities = 63/169 (37%), Positives = 76/169 (44%), Gaps = 18/169 (10%)
Query: 119 VNECAAFPGLCGH-GRCRNLLG-GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
VN C +C RC G +TC+C GY+ D +N CVD NEC CG
Sbjct: 760 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRN--CVDENECATGFHRCGPNSV 817
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDI----DECADNDALCR---GGRCVNTAGS-FRC 227
C N GS+ C CR GY+ D C+ I + C D C RCV+ GS F C
Sbjct: 818 CINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSC 877
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
C G A D C D+DECS C A C N G++ C C GY
Sbjct: 878 ACLPG--YAGDGHQCTDVDECS--ENRCHPAATCYNTPGSFSCRCQPGY 922
Score = 87.0 bits (206), Expect = 2e-16
Identities = 63/191 (32%), Positives = 81/191 (42%), Gaps = 23/191 (12%)
Query: 161 VNECEIVDGVCGD-GDCHNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR- 217
VN C +C CH G +TC C GY+ D + CVD +ECA C
Sbjct: 760 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGD--GRNCVDENECATGFHRCGPNSV 817
Query: 218 CVNTAGSFRCECGHGMELAPDRLSC----KDIDECSITSGICS---NGACENQMG-TYQC 269
C+N GS+RCEC G E A DR +C + C S C+ C + G T+ C
Sbjct: 818 CINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSC 877
Query: 270 VCDEGYAQSTVKSHXXXXXXXXXXXXRCQ--HSCVNTPGSYHCTCREGWHLRADGRSCRD 327
C GYA H RC +C NTPGS+ C C+ G++ DG C
Sbjct: 878 ACLPGYAGD---GH-QCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYY--GDGFQC-- 929
Query: 328 IDECAGGARPC 338
I + PC
Sbjct: 930 IPDSTSSLTPC 940
Score = 85.8 bits (203), Expect = 4e-16
Identities = 52/140 (37%), Positives = 65/140 (46%), Gaps = 19/140 (13%)
Query: 117 MEVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCV----DVNECEIVDGVC 171
++ NECA CG + C NL G + C+C GYE HTC+ N CE C
Sbjct: 800 VDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTC 859
Query: 172 ---GDGDC-HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR 226
G C H+ +F+C C PGY D C D+DEC++N C C NT GSF
Sbjct: 860 APAGQARCVHHGGSTFSCACLPGYAGDGHQ--CTDVDECSEN--RCHPAATCYNTPGSFS 915
Query: 227 CEC-----GHGMELAPDRLS 241
C C G G + PD S
Sbjct: 916 CRCQPGYYGDGFQCIPDSTS 935
Score = 70.1 bits (164), Expect = 2e-11
Identities = 44/154 (28%), Positives = 63/154 (40%), Gaps = 15/154 (9%)
Query: 422 YSVKPEQGPACTDDDECELGTCD-----CHPAADCINLPG-SFQCRCRDGWRGDGATCED 475
++V + GP D D + C C A C G + C C G++GDG C D
Sbjct: 742 FAVTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVD 801
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
+EC T C P + C N GS+RC C +GY+ + C+ + C +
Sbjct: 802 ENECATGFHRCGPNSVCINLPGSYRCECRSGYE---FADDRHTCILITPPANPCEDGSHT 858
Query: 536 CE---NGHCSNTPGG-YECDCDVGFTRAADGRSC 565
C C + G + C C G+ A DG C
Sbjct: 859 CAPAGQARCVHHGGSTFSCACLPGY--AGDGHQC 890
Score = 56.8 bits (131), Expect = 2e-07
Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 11/93 (11%)
Query: 476 VDECLTNNGGCHPRATC-ANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
V+ C + C A C T + C C +GY+GDG +CVD +ECA
Sbjct: 760 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGR---------NCVDENECATGFH 810
Query: 535 LC-ENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C N C N PG Y C+C G+ A D +C+
Sbjct: 811 RCGPNSVCINLPGSYRCECRSGYEFADDRHTCI 843
>AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein.
Length = 1376
Score = 101 bits (241), Expect = 9e-21
Identities = 53/118 (44%), Positives = 63/118 (53%), Gaps = 9/118 (7%)
Query: 402 CGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACT---DDDECELGTCDCHPA--ADCINLP 455
CG S C N GS+ C+C GY ++ + CE G+ C PA A C++
Sbjct: 813 CGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHG 872
Query: 456 GS-FQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
GS F C C G+ GDG C DVDEC N CHP ATC NT GSF C C GY GDG+
Sbjct: 873 GSTFSCACLPGYAGDGHQCTDVDECSENR--CHPAATCYNTPGSFSCRCQPGYYGDGF 928
Score = 100 bits (240), Expect = 1e-20
Identities = 61/171 (35%), Positives = 80/171 (46%), Gaps = 27/171 (15%)
Query: 407 CHNTIG-SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
CH G + C+C GY G C D++EC G C P + CINLPGS++C CR G
Sbjct: 777 CHPGTGVDYTCECASGYQ---GDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSG 833
Query: 466 WR--GDGATC----EDVDECLTNNGGCHP--RATCANTDGS-FRCLCDTGYKGDGYGLRT 516
+ D TC + C + C P +A C + GS F C C GY GDG+
Sbjct: 834 YEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGH---- 889
Query: 517 VCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTRAADGRSCL 566
C D+DEC+ + C C NTPG + C C G+ DG C+
Sbjct: 890 -----QCTDVDECSENR--CHPAATCYNTPGSFSCRCQPGY--YGDGFQCI 931
Score = 96.7 bits (230), Expect = 2e-19
Identities = 62/168 (36%), Positives = 75/168 (44%), Gaps = 24/168 (14%)
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAK 366
Y C C G+ + DGR+C D +ECA G CG C N GSY C C G A +
Sbjct: 785 YTCECASGY--QGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGY--EFADDR 840
Query: 367 PTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC-HNTIGSFVCQCPDGYSVK 425
TC +I + + P G C H+ +F C C GY+
Sbjct: 841 HTC-----------ILITPPANPCEDGSHTCAP--AGQARCVHHGGSTFSCACLPGYA-- 885
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC 473
G CTD DEC C HPAA C N PGSF CRC+ G+ GDG C
Sbjct: 886 -GDGHQCTDVDECSENRC--HPAATCYNTPGSFSCRCQPGYYGDGFQC 930
Score = 93.1 bits (221), Expect = 2e-18
Identities = 63/169 (37%), Positives = 76/169 (44%), Gaps = 18/169 (10%)
Query: 119 VNECAAFPGLCGH-GRCRNLLG-GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
VN C +C RC G +TC+C GY+ D +N CVD NEC CG
Sbjct: 761 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRN--CVDENECATGFHRCGPNSV 818
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDI----DECADNDALCR---GGRCVNTAGS-FRC 227
C N GS+ C CR GY+ D C+ I + C D C RCV+ GS F C
Sbjct: 819 CINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSC 878
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
C G A D C D+DECS C A C N G++ C C GY
Sbjct: 879 ACLPG--YAGDGHQCTDVDECS--ENRCHPAATCYNTPGSFSCRCQPGY 923
Score = 87.0 bits (206), Expect = 2e-16
Identities = 63/191 (32%), Positives = 81/191 (42%), Gaps = 23/191 (12%)
Query: 161 VNECEIVDGVCGD-GDCHNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR- 217
VN C +C CH G +TC C GY+ D + CVD +ECA C
Sbjct: 761 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGD--GRNCVDENECATGFHRCGPNSV 818
Query: 218 CVNTAGSFRCECGHGMELAPDRLSC----KDIDECSITSGICS---NGACENQMG-TYQC 269
C+N GS+RCEC G E A DR +C + C S C+ C + G T+ C
Sbjct: 819 CINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSC 878
Query: 270 VCDEGYAQSTVKSHXXXXXXXXXXXXRCQ--HSCVNTPGSYHCTCREGWHLRADGRSCRD 327
C GYA H RC +C NTPGS+ C C+ G++ DG C
Sbjct: 879 ACLPGYAGD---GH-QCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYY--GDGFQC-- 930
Query: 328 IDECAGGARPC 338
I + PC
Sbjct: 931 IPDSTSSLTPC 941
Score = 85.8 bits (203), Expect = 4e-16
Identities = 52/140 (37%), Positives = 65/140 (46%), Gaps = 19/140 (13%)
Query: 117 MEVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCV----DVNECEIVDGVC 171
++ NECA CG + C NL G + C+C GYE HTC+ N CE C
Sbjct: 801 VDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTC 860
Query: 172 ---GDGDC-HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR 226
G C H+ +F+C C PGY D C D+DEC++N C C NT GSF
Sbjct: 861 APAGQARCVHHGGSTFSCACLPGYAGDGHQ--CTDVDECSEN--RCHPAATCYNTPGSFS 916
Query: 227 CEC-----GHGMELAPDRLS 241
C C G G + PD S
Sbjct: 917 CRCQPGYYGDGFQCIPDSTS 936
Score = 70.1 bits (164), Expect = 2e-11
Identities = 44/154 (28%), Positives = 63/154 (40%), Gaps = 15/154 (9%)
Query: 422 YSVKPEQGPACTDDDECELGTCD-----CHPAADCINLPG-SFQCRCRDGWRGDGATCED 475
++V + GP D D + C C A C G + C C G++GDG C D
Sbjct: 743 FAVTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVD 802
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
+EC T C P + C N GS+RC C +GY+ + C+ + C +
Sbjct: 803 ENECATGFHRCGPNSVCINLPGSYRCECRSGYE---FADDRHTCILITPPANPCEDGSHT 859
Query: 536 CE---NGHCSNTPGG-YECDCDVGFTRAADGRSC 565
C C + G + C C G+ A DG C
Sbjct: 860 CAPAGQARCVHHGGSTFSCACLPGY--AGDGHQC 891
Score = 56.8 bits (131), Expect = 2e-07
Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 11/93 (11%)
Query: 476 VDECLTNNGGCHPRATC-ANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
V+ C + C A C T + C C +GY+GDG +CVD +ECA
Sbjct: 761 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGR---------NCVDENECATGFH 811
Query: 535 LC-ENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C N C N PG Y C+C G+ A D +C+
Sbjct: 812 RCGPNSVCINLPGSYRCECRSGYEFADDRHTCI 844
>AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein.
Length = 1055
Score = 99.5 bits (237), Expect = 3e-20
Identities = 80/277 (28%), Positives = 116/277 (41%), Gaps = 46/277 (16%)
Query: 252 SGICS-NGACENQMG-TYQCVCDEGYAQSTVK--SHXXXXXXXXXXXXRCQHSCVNT--P 305
S CS NG C + +G C+C+EG+ S + S C H N
Sbjct: 178 SNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRID 237
Query: 306 GSYHC---TCREGWHLRADGRSC-RDIDECAGGARPCG-GGQCRNTVGSYTCTCTDGLVP 360
C TCR+G + GR C + C + C C + G+ +C C G
Sbjct: 238 SDGACLTGTCRDG----SAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGY-- 291
Query: 361 SAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGS-CHNT-IGSFVCQC 418
G C ++D C L P C + C NT G+ C C
Sbjct: 292 --EGDGTLCSEMDPCTGLT-------------------PGGCSRNAECINTGTGTHTCVC 330
Query: 419 PDGYSVKPEQGPACTDDDECELGTCD-CHPAADCINL-PGSFQCRCRDGWRGDGATCEDV 476
G++ G C++ + C L + CH A C+ + PG +C C+ G+RG+G CE +
Sbjct: 331 QQGWT---GNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPI 387
Query: 477 DECLTNNGGCHPRATCANT-DGSFRCLCDTGYKGDGY 512
CL G CHP A+C +T G + C+C GY+GDG+
Sbjct: 388 TSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGF 424
Score = 88.2 bits (209), Expect = 7e-17
Identities = 65/232 (28%), Positives = 99/232 (42%), Gaps = 26/232 (11%)
Query: 340 GGQCRNTVGSYTCTCT-DGLVPSAAGAKPTCQDIDECADLISTIIMMSVDELQKSVDPQI 398
G QC+ G+ C +G+ C EC + S + E + +
Sbjct: 775 GPQCQPCPGNAQNVCFGNGICLDGVNGTGVC----ECGEGFSGTACETCTEGKYGIHCDQ 830
Query: 399 PELCGAGSCHN-TIGSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCI-NLPG 456
C G C+ +G C C G+ + T +D C GTC H +A+C+ N G
Sbjct: 831 ACSCVHGRCNQGPLGDGSCDCDVGW--RGVHCDNATTEDNCN-GTC--HTSANCLTNSDG 885
Query: 457 SFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFR-CLCDTGYKGDGYGLR 515
+ C+C G++G+G C ++ C +NGGC +A C T R C C GY GDG
Sbjct: 886 TASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGI--- 942
Query: 516 TVCCVYSCVDIDECANDPTLCE-NGHCSNT-PGGYECDCDVGFTRAADGRSC 565
C++I+ C + C+ N C+ T P C+C +T DG+ C
Sbjct: 943 ------VCLEINPCLENHCGCDKNAECTQTGPNQAACNCLPAYT--GDGKVC 986
Score = 80.2 bits (189), Expect = 2e-14
Identities = 73/241 (30%), Positives = 98/241 (40%), Gaps = 43/241 (17%)
Query: 327 DIDECAGG-ARPCGG-GQCRNTVGSY-TCTCTDGLVPSAAGAKPTCQDIDECADLISTII 383
D ++C GG + PC G GQC +++G TC C +G S CQ C+D
Sbjct: 169 DCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQ------CQF---CSD------ 213
Query: 384 MMSVDELQKSVDPQIPE--LCGAGSCHNTIGSFVCQCPDGYSVKPEQGPACTDDDE-CEL 440
P+ + LC G+C+N I S C G G C C
Sbjct: 214 -------PNKYGPRCNKKCLCVHGTCNNRIDSDGA-CLTGTCRDGSAGRLCDKQTSACGP 265
Query: 441 GTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECL-TNNGGCHPRATCANTD-GS 498
CH A C G+ C C+ G+ GDG C ++D C GGC A C NT G+
Sbjct: 266 YVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECINTGTGT 325
Query: 499 FRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL-C-ENGHCSNT-PGGYECDCDVG 555
C+C G+ G+G C +I+ C C +N C PG EC+C G
Sbjct: 326 HTCVCQQGWTGNGR---------DCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKG 376
Query: 556 F 556
F
Sbjct: 377 F 377
Score = 74.9 bits (176), Expect = 7e-13
Identities = 59/175 (33%), Positives = 80/175 (45%), Gaps = 31/175 (17%)
Query: 403 GAGSCHNTI-GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLP------ 455
G G C + + G+ VC+C +G+S G AC E + G C A C++
Sbjct: 791 GNGICLDGVNGTGVCECGEGFS-----GTACETCTEGKYGI-HCDQACSCVHGRCNQGPL 844
Query: 456 GSFQCRCRDGWRG---DGATCEDVDECLTNNGGCHPRATC-ANTDGSFRCLCDTGYKGDG 511
G C C GWRG D AT E D C NG CH A C N+DG+ C C G++G+G
Sbjct: 845 GDGSCDCDVGWRGVHCDNATTE--DNC---NGTCHTSANCLTNSDGTASCKCAAGFQGNG 899
Query: 512 YGLRTVCCVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
T+C + ++ E +N + TPG C C G+T DG CL
Sbjct: 900 ----TIC---TAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYT--GDGIVCL 945
Score = 71.3 bits (167), Expect = 8e-12
Identities = 89/357 (24%), Positives = 124/357 (34%), Gaps = 51/357 (14%)
Query: 159 VDVNECEIVDGVCGDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRG--G 216
+ N C+ D G C TC ++ + C+ L G
Sbjct: 700 IQKNRCDNNDTTIIRGRCRTCSSELTCPFGTKSLGNE-KRRCIYTSYFMGRRTLFIGCQP 758
Query: 217 RCVNTAGSFRCECGH-GMELAPDRLSCKDIDECSITSGICSNGACENQMGTYQCVCDEGY 275
+CV T + C G G + P + +++ C +GIC +G GT C C EG+
Sbjct: 759 KCVRTVITRECCAGFFGPQCQPCPGNAQNV--C-FGNGICLDGV----NGTGVCECGEGF 811
Query: 276 AQSTVKSHXXXXXXXXXXXX-RCQHS-CVNTP-GSYHCTCREGWH-LRADGRSCRDIDEC 331
+ + ++ C H C P G C C GW + D + D C
Sbjct: 812 SGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTED--NC 869
Query: 332 AGGARPCGGGQC-RNTVGSYTCTCTDGLVPSAAGAKPTCQDIDECADLISTIIMMSVDEL 390
G C N+ G+ +C C G G C I+ C E+
Sbjct: 870 NGTCHT--SANCLTNSDGTASCKCAAGF----QGNGTICTAINAC-------------EI 910
Query: 391 QKSVDPQIPELCGA-GSCHNTI-GSFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPA 448
C A C T G VC C GY+ G C + + C C C
Sbjct: 911 SNGG-------CSAKADCKRTTPGRRVCTCKAGYT---GDGIVCLEINPCLENHCGCDKN 960
Query: 449 ADCINL-PGSFQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFR-CLC 503
A+C P C C + GDG C ++ CLT NGGC A C +T R C C
Sbjct: 961 AECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTC 1017
Score = 64.1 bits (149), Expect = 1e-09
Identities = 70/290 (24%), Positives = 104/290 (35%), Gaps = 52/290 (17%)
Query: 196 FSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
FS C +CAD+ L G C+ G +C + P++ + +C G C
Sbjct: 177 FSNPCSGNGQCADS--LGGNGTCICEEGFQGSQCQFCSD--PNKYGPRCNKKCLCVHGTC 232
Query: 256 SNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQHSCVNTPGSYHCTCREG 315
+N ++ C +G A + +C + G+ C C+ G
Sbjct: 233 NN-RIDSDGACLTGTCRDGSA-GRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAG 290
Query: 316 WHLRADGRSCRDIDECAGGARPCG---GGQCRNT-VGSYTCTCTDGLVPSAAGAKPTCQD 371
+ DG C ++D C G P G +C NT G++TC C G G C +
Sbjct: 291 YE--GDGTLCSEMDPCTG-LTPGGCSRNAECINTGTGTHTCVCQQGWT----GNGRDCSE 343
Query: 372 IDECADLISTIIMMSVDELQKSVDPQIPELCGAGSCHNTI-------GSFVCQCPDGYSV 424
I+ C L AG CH+ G C+C G+
Sbjct: 344 INNCL------------------------LPSAGGCHDNASCLYVGPGQNECECKKGFR- 378
Query: 425 KPEQGPACTDDDECELGTCDCHPAADCINLP-GSFQCRCRDGWRGDGATC 473
G C C T CHP A C + G + C C++G+ GDG C
Sbjct: 379 --GNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLC 426
Score = 64.1 bits (149), Expect = 1e-09
Identities = 42/146 (28%), Positives = 62/146 (42%), Gaps = 8/146 (5%)
Query: 139 GGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCG-DGDC-HNTEGSFTCHCRPGYKADDF 196
G +C C G++ + C +N CEI +G C DC T G C C+ GY D
Sbjct: 885 GTASCKCAAGFQGNGT--ICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGI 942
Query: 197 SKICVDIDECADNDALC-RGGRCVNTAGSFRCECGHGMELAPDRLSCKDIDECSITSGIC 255
+C++I+ C +N C + C T G + C D C I+ C +G C
Sbjct: 943 --VCLEINPCLENHCGCDKNAECTQT-GPNQAACNCLPAYTGDGKVCTLINVCLTKNGGC 999
Query: 256 SNGACENQMGTYQCVCDEGYAQSTVK 281
S A N G + C Q+T++
Sbjct: 1000 SEFAICNHTGQVERTCTCKGPQTTLE 1025
Score = 63.3 bits (147), Expect = 2e-09
Identities = 53/208 (25%), Positives = 80/208 (38%), Gaps = 17/208 (8%)
Query: 128 LCGHGRCRNLLGGFTCDCFPGYEKD-SKNHTC-VDVNECEIVDGVCG-DGDCHNTEGSFT 184
LC HG C N + C G +D S C + C C C + G+ +
Sbjct: 226 LCVHGTCNNRIDSDGA-CLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTAS 284
Query: 185 CHCRPGYKADDFSKICVDIDECA--DNDALCRGGRCVNT-AGSFRCECGHGMELAPDRLS 241
C C+ GY+ D +C ++D C R C+NT G+ C C G +
Sbjct: 285 CICKAGYEGD--GTLCSEMDPCTGLTPGGCSRNAECINTGTGTHTCVCQQGW--TGNGRD 340
Query: 242 CKDIDECSITS--GICSNGAC-ENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQ 298
C +I+ C + S G N +C G +C C +G+ + +
Sbjct: 341 CSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPL 400
Query: 299 HSCVNT-PGSYHCTCREGWHLRADGRSC 325
SC +T G + C C+EG+ DG C
Sbjct: 401 ASCQSTSSGVWSCVCQEGY--EGDGFLC 426
Score = 48.4 bits (110), Expect = 7e-05
Identities = 63/257 (24%), Positives = 87/257 (33%), Gaps = 39/257 (15%)
Query: 121 ECAAFPG----LC-GHGRCRNLLGGF-TCDCFPGYEKDSKNHTCVDVN-------ECEIV 167
+C PG +C G+G C + + G C+C G+ + TC + C V
Sbjct: 777 QCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFS-GTACETCTEGKYGIHCDQACSCV 835
Query: 168 DGVC-----GDGDCHNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTA 222
G C GDG C G HC D+ + C C N+
Sbjct: 836 HGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANC-----------LTNSD 884
Query: 223 GSFRCECGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQM-GTYQCVCDEGYAQSTV 280
G+ C+C G + + C I+ C I++G CS A C+ G C C GY +
Sbjct: 885 GTASCKCAAGFQ--GNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGI 942
Query: 281 KSHXXXXXXXXXXXXRCQHSCVNT-PGSYHCTCREGWHLRADGRSCRDIDECAGGARPCG 339
C T P C C + DG+ C I+ C C
Sbjct: 943 VCLEINPCLENHCGCDKNAECTQTGPNQAACNCLPAY--TGDGKVCTLINVCLTKNGGCS 1000
Query: 340 GGQCRNTVGSY--TCTC 354
N G TCTC
Sbjct: 1001 EFAICNHTGQVERTCTC 1017
>BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein.
Length = 969
Score = 98.7 bits (235), Expect = 5e-20
Identities = 52/118 (44%), Positives = 62/118 (52%), Gaps = 9/118 (7%)
Query: 402 CGAGS-CHNTIGSFVCQCPDGYSVKPEQGPACT---DDDECELGTCDCHPA--ADCINLP 455
CG S C N GS+ C+C Y ++ + CE G+ C PA A C++
Sbjct: 406 CGPNSVCINLPGSYRCECRSAYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHG 465
Query: 456 GS-FQCRCRDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGY 512
GS F C C G+ GDG C DVDEC N CHP ATC NT GSF C C GY GDG+
Sbjct: 466 GSTFSCACLPGYAGDGHQCTDVDECSENR--CHPAATCYNTPGSFSCRCQPGYYGDGF 521
Score = 98.3 bits (234), Expect = 6e-20
Identities = 60/171 (35%), Positives = 79/171 (46%), Gaps = 27/171 (15%)
Query: 407 CHNTIG-SFVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDG 465
CH G + C+C GY G C D++EC G C P + CINLPGS++C CR
Sbjct: 370 CHPGTGVDYTCECASGYQ---GDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSA 426
Query: 466 WR--GDGATC----EDVDECLTNNGGCHP--RATCANTDGS-FRCLCDTGYKGDGYGLRT 516
+ D TC + C + C P +A C + GS F C C GY GDG+
Sbjct: 427 YEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGH---- 482
Query: 517 VCCVYSCVDIDECANDPTLCENGH-CSNTPGGYECDCDVGFTRAADGRSCL 566
C D+DEC+ + C C NTPG + C C G+ DG C+
Sbjct: 483 -----QCTDVDECSENR--CHPAATCYNTPGSFSCRCQPGY--YGDGFQCI 524
Score = 94.3 bits (224), Expect = 1e-18
Identities = 61/168 (36%), Positives = 74/168 (44%), Gaps = 24/168 (14%)
Query: 308 YHCTCREGWHLRADGRSCRDIDECAGGARPCGGGQ-CRNTVGSYTCTCTDGLVPSAAGAK 366
Y C C G+ + DGR+C D +ECA G CG C N GSY C C A +
Sbjct: 378 YTCECASGY--QGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSAY--EFADDR 433
Query: 367 PTCQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC-HNTIGSFVCQCPDGYSVK 425
TC +I + + P G C H+ +F C C GY+
Sbjct: 434 HTC-----------ILITPPANPCEDGSHTCAP--AGQARCVHHGGSTFSCACLPGYA-- 478
Query: 426 PEQGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATC 473
G CTD DEC C HPAA C N PGSF CRC+ G+ GDG C
Sbjct: 479 -GDGHQCTDVDECSENRC--HPAATCYNTPGSFSCRCQPGYYGDGFQC 523
Score = 90.6 bits (215), Expect = 1e-17
Identities = 62/169 (36%), Positives = 75/169 (44%), Gaps = 18/169 (10%)
Query: 119 VNECAAFPGLCGH-GRCRNLLG-GFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD- 175
VN C +C RC G +TC+C GY+ D +N CVD NEC CG
Sbjct: 354 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRN--CVDENECATGFHRCGPNSV 411
Query: 176 CHNTEGSFTCHCRPGYKADDFSKICVDI----DECADNDALCR---GGRCVNTAGS-FRC 227
C N GS+ C CR Y+ D C+ I + C D C RCV+ GS F C
Sbjct: 412 CINLPGSYRCECRSAYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSC 471
Query: 228 ECGHGMELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
C G A D C D+DECS C A C N G++ C C GY
Sbjct: 472 ACLPG--YAGDGHQCTDVDECS--ENRCHPAATCYNTPGSFSCRCQPGY 516
Score = 84.6 bits (200), Expect = 8e-16
Identities = 62/191 (32%), Positives = 80/191 (41%), Gaps = 23/191 (12%)
Query: 161 VNECEIVDGVCGD-GDCHNTEG-SFTCHCRPGYKADDFSKICVDIDECADNDALCRGGR- 217
VN C +C CH G +TC C GY+ D + CVD +ECA C
Sbjct: 354 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGD--GRNCVDENECATGFHRCGPNSV 411
Query: 218 CVNTAGSFRCECGHGMELAPDRLSC----KDIDECSITSGICS---NGACENQMG-TYQC 269
C+N GS+RCEC E A DR +C + C S C+ C + G T+ C
Sbjct: 412 CINLPGSYRCECRSAYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSC 471
Query: 270 VCDEGYAQSTVKSHXXXXXXXXXXXXRCQ--HSCVNTPGSYHCTCREGWHLRADGRSCRD 327
C GYA H RC +C NTPGS+ C C+ G++ DG C
Sbjct: 472 ACLPGYAGD---GH-QCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYY--GDGFQC-- 523
Query: 328 IDECAGGARPC 338
I + PC
Sbjct: 524 IPDSTSSLTPC 534
Score = 83.4 bits (197), Expect = 2e-15
Identities = 51/140 (36%), Positives = 64/140 (45%), Gaps = 19/140 (13%)
Query: 117 MEVNECAAFPGLCG-HGRCRNLLGGFTCDCFPGYEKDSKNHTCV----DVNECEIVDGVC 171
++ NECA CG + C NL G + C+C YE HTC+ N CE C
Sbjct: 394 VDENECATGFHRCGPNSVCINLPGSYRCECRSAYEFADDRHTCILITPPANPCEDGSHTC 453
Query: 172 ---GDGDC-HNTEGSFTCHCRPGYKADDFSKICVDIDECADNDALCR-GGRCVNTAGSFR 226
G C H+ +F+C C PGY D C D+DEC++N C C NT GSF
Sbjct: 454 APAGQARCVHHGGSTFSCACLPGYAGDGHQ--CTDVDECSEN--RCHPAATCYNTPGSFS 509
Query: 227 CEC-----GHGMELAPDRLS 241
C C G G + PD S
Sbjct: 510 CRCQPGYYGDGFQCIPDSTS 529
Score = 67.7 bits (158), Expect = 1e-10
Identities = 43/154 (27%), Positives = 62/154 (40%), Gaps = 15/154 (9%)
Query: 422 YSVKPEQGPACTDDDECELGTCD-----CHPAADCINLPG-SFQCRCRDGWRGDGATCED 475
++V + GP D D + C C A C G + C C G++GDG C D
Sbjct: 336 FAVTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVD 395
Query: 476 VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTL 535
+EC T C P + C N GS+RC C + Y+ + C+ + C +
Sbjct: 396 ENECATGFHRCGPNSVCINLPGSYRCECRSAYE---FADDRHTCILITPPANPCEDGSHT 452
Query: 536 CE---NGHCSNTPGG-YECDCDVGFTRAADGRSC 565
C C + G + C C G+ A DG C
Sbjct: 453 CAPAGQARCVHHGGSTFSCACLPGY--AGDGHQC 484
Score = 54.4 bits (125), Expect = 1e-06
Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 11/93 (11%)
Query: 476 VDECLTNNGGCHPRATC-ANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPT 534
V+ C + C A C T + C C +GY+GDG +CVD +ECA
Sbjct: 354 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGR---------NCVDENECATGFH 404
Query: 535 LC-ENGHCSNTPGGYECDCDVGFTRAADGRSCL 566
C N C N PG Y C+C + A D +C+
Sbjct: 405 RCGPNSVCINLPGSYRCECRSAYEFADDRHTCI 437
>AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein.
Length = 723
Score = 98.7 bits (235), Expect = 5e-20
Identities = 77/243 (31%), Positives = 102/243 (41%), Gaps = 30/243 (12%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNT 179
+EC +PG C HG C+ + C+C G+ N D+N C C NT
Sbjct: 255 DECIRYPG-CLHGTCQQ---PWQCNCQEGWGGLFCNQ---DLNYCTHHKPCKNGATCTNT 307
Query: 180 -EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
+GS+TC CRPGY + IDEC D GG C + S+ C C G
Sbjct: 308 GQGSYTCSCRPGYTGATCE---LGIDEC-DPSPCKNGGSCTDLENSYSCTCPPGFYGKIC 363
Query: 239 RLSCKDIDECSITSGICSNGA-CENQM-GTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
LS C+ G C NG C + G Y C C GY+ +
Sbjct: 364 ELSAMT---CA--DGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGA 418
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCG-GGQCRNTVGSYTCTC 354
CV+ +Y C C+ G+ GR C D +D+CA PC GG CR+ V ++CTC
Sbjct: 419 ---KCVDLGDAYLCRCQAGF----SGRHCDDNVDDCASS--PCANGGTCRDGVNDFSCTC 469
Query: 355 TDG 357
G
Sbjct: 470 PPG 472
Score = 91.1 bits (216), Expect = 1e-17
Identities = 78/278 (28%), Positives = 111/278 (39%), Gaps = 45/278 (16%)
Query: 301 CVNTPGSYHCTCREGWHLRAD----GRSC-RDIDECAGGARPC-GGGQCRNT-VGSYTCT 353
C+ PG H TC++ W G C +D++ C +PC G C NT GSYTC+
Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHH-KPCKNGATCTNTGQGSYTCS 315
Query: 354 CTDGLVPSAAG-----AKPT-CQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
C G + P+ C++ C DL ++ + C G C
Sbjct: 316 CRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPC 375
Query: 408 HN-------TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQ 459
N G + C+CP GYS G C D C + C A C++L ++
Sbjct: 376 FNGGRCSDSPDGGYSCRCPVGYS-----GFNCEKKIDYCS--SSPCSNGAKCVDLGDAYL 428
Query: 460 CRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
CRC+ G+ G C+D VD+C ++ C TC + F C C GY G
Sbjct: 429 CRCQAGF--SGRHCDDNVDDCASS--PCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSR 484
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
C ++ C N T E GH Y C+C G+
Sbjct: 485 CEHA-----PCHNGATCHERGH------RYVCECARGY 511
Score = 83.4 bits (197), Expect = 2e-15
Identities = 92/347 (26%), Positives = 132/347 (38%), Gaps = 49/347 (14%)
Query: 187 CRPGYKADDFSKI-CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD- 244
CRP + D F C + E N +G C C+ HG P C+
Sbjct: 192 CRP--RDDAFGHFTCGERGEKVCNPGW-KGPYCTEPICLPGCDEQHGFCDKPGECKCRVG 248
Query: 245 -----IDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
DEC G C +G C+ +QC C EG+ + + +
Sbjct: 249 WQGRYCDECIRYPG-CLHGTCQQP---WQCNCQEGWGG--LFCNQDLNYCTHHKPCKNGA 302
Query: 300 SCVNT-PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTD 356
+C NT GSY C+CR G+ G +C IDEC PC GG C + SY+CTC
Sbjct: 303 TCTNTGQGSYTCSCRPGY----TGATCELGIDEC--DPSPCKNGGSCTDLENSYSCTCPP 356
Query: 357 GL------VPSAAGAKPTCQDIDECADL------ISTIIMMSVDELQKSVDPQIPELCGA 404
G + + A C + C+D + S +K +D C
Sbjct: 357 GFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSN 416
Query: 405 GS-CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
G+ C + +++C+C G+S G C D+ D+C + C C + F C C
Sbjct: 417 GAKCVDLGDAYLCRCQAGFS-----GRHCDDNVDDC--ASSPCANGGTCRDGVNDFSCTC 469
Query: 463 RDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G+ G + V C + CH ATC + C C GY G
Sbjct: 470 PPGYTGRNCSAP-VSRC--EHAPCHNGATCHERGHRYVCECARGYGG 513
Score = 68.9 bits (161), Expect = 4e-11
Identities = 50/157 (31%), Positives = 68/157 (43%), Gaps = 24/157 (15%)
Query: 405 GSCHNTIGS-FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINL-PGSFQCRC 462
G H T + C C +G+ G C D C A C N GS+ C C
Sbjct: 262 GCLHGTCQQPWQCNCQEGWG-----GLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316
Query: 463 RDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
R G+ G ATCE +DEC + C +C + + S+ C C G+ G C
Sbjct: 317 RPGYTG--ATCELGIDEC--DPSPCKNGGSCTDLENSYSCTCPPGFYGK-------ICEL 365
Query: 522 SCVDIDECANDPTLCENGHCSNTP-GGYECDCDVGFT 557
S + CA+ P G CS++P GGY C C VG++
Sbjct: 366 SAMT---CADGPCF-NGGRCSDSPDGGYSCRCPVGYS 398
Score = 67.7 bits (158), Expect = 1e-10
Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++ ++EC P G G C +L ++C C PG+ C +++ DG C +G
Sbjct: 326 ELGIDECDPSPCKNG-GSCTDLENSYSCTCPPGFY----GKIC-ELSAMTCADGPCFNGG 379
Query: 176 -CHNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C ++ +G ++C C GY + K ID C+ + G +CV+ ++ C C G
Sbjct: 380 RCSDSPDGGYSCRCPVGYSGFNCEK---KIDYCSSSPC-SNGAKCVDLGDAYLCRCQAGF 435
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
R ++D+C+ S C+NG C + + + C C GY
Sbjct: 436 S---GRHCDDNVDDCA--SSPCANGGTCRDGVNDFSCTCPPGY 473
Score = 47.2 bits (107), Expect = 2e-04
Identities = 43/134 (32%), Positives = 61/134 (45%), Gaps = 29/134 (21%)
Query: 428 QGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCH 487
+GP CT+ C G + H D PG +C+CR GW+G C DEC+ G H
Sbjct: 217 KGPYCTEPI-CLPGCDEQHGFCD---KPG--ECKCRVGWQG--RYC---DECIRYPGCLH 265
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNT-P 545
TC ++C C G+ G ++ D++ C + C+NG C+NT
Sbjct: 266 --GTCQQP---WQCNCQEGWGG----------LFCNQDLNYCTHHKP-CKNGATCTNTGQ 309
Query: 546 GGYECDCDVGFTRA 559
G Y C C G+T A
Sbjct: 310 GSYTCSCRPGYTGA 323
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCH 177
V++CA+ P G G CR+ + F+C C PGY + + V+ CE C +G CH
Sbjct: 444 VDDCASSPCANG-GTCRDGVNDFSCTCPPGY---TGRNCSAPVSRCE--HAPCHNGATCH 497
Query: 178 NTEGSFTCHCRPGY 191
+ C C GY
Sbjct: 498 ERGHRYVCECARGY 511
>AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophila)
protein.
Length = 723
Score = 98.7 bits (235), Expect = 5e-20
Identities = 77/243 (31%), Positives = 102/243 (41%), Gaps = 30/243 (12%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNT 179
+EC +PG C HG C+ + C+C G+ N D+N C C NT
Sbjct: 255 DECIRYPG-CLHGTCQQ---PWQCNCQEGWGGLFCNQ---DLNYCTHHKPCKNGATCTNT 307
Query: 180 -EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
+GS+TC CRPGY + IDEC D GG C + S+ C C G
Sbjct: 308 GQGSYTCSCRPGYTGATCE---LGIDEC-DPSPCKNGGSCTDLENSYSCTCPPGFYGKIC 363
Query: 239 RLSCKDIDECSITSGICSNGA-CENQM-GTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
LS C+ G C NG C + G Y C C GY+ +
Sbjct: 364 ELSAMT---CA--DGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGA 418
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCG-GGQCRNTVGSYTCTC 354
CV+ +Y C C+ G+ GR C D +D+CA PC GG CR+ V ++CTC
Sbjct: 419 ---KCVDLGDAYLCRCQAGF----SGRHCDDNVDDCASS--PCANGGTCRDGVNDFSCTC 469
Query: 355 TDG 357
G
Sbjct: 470 PPG 472
Score = 91.1 bits (216), Expect = 1e-17
Identities = 78/278 (28%), Positives = 111/278 (39%), Gaps = 45/278 (16%)
Query: 301 CVNTPGSYHCTCREGWHLRAD----GRSC-RDIDECAGGARPC-GGGQCRNT-VGSYTCT 353
C+ PG H TC++ W G C +D++ C +PC G C NT GSYTC+
Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHH-KPCKNGATCTNTGQGSYTCS 315
Query: 354 CTDGLVPSAAG-----AKPT-CQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
C G + P+ C++ C DL ++ + C G C
Sbjct: 316 CRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPC 375
Query: 408 HN-------TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQ 459
N G + C+CP GYS G C D C + C A C++L ++
Sbjct: 376 FNGGRCSDSPDGGYSCRCPVGYS-----GFNCEKKIDYCS--SSPCSNGAKCVDLGDAYL 428
Query: 460 CRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
CRC+ G+ G C+D VD+C ++ C TC + F C C GY G
Sbjct: 429 CRCQAGF--SGRHCDDNVDDCASS--PCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSR 484
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
C ++ C N T E GH Y C+C G+
Sbjct: 485 CEHA-----PCHNGATCHERGH------RYVCECARGY 511
Score = 83.4 bits (197), Expect = 2e-15
Identities = 92/347 (26%), Positives = 132/347 (38%), Gaps = 49/347 (14%)
Query: 187 CRPGYKADDFSKI-CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD- 244
CRP + D F C + E N +G C C+ HG P C+
Sbjct: 192 CRP--RDDAFGHFTCGERGEKVCNPGW-KGPYCTEPICLPGCDEQHGFCDKPGECKCRVG 248
Query: 245 -----IDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
DEC G C +G C+ +QC C EG+ + + +
Sbjct: 249 WQGRYCDECIRYPG-CLHGTCQQP---WQCNCQEGWGG--LFCNQDLNYCTHHKPCKNGA 302
Query: 300 SCVNT-PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTD 356
+C NT GSY C+CR G+ G +C IDEC PC GG C + SY+CTC
Sbjct: 303 TCTNTGQGSYTCSCRPGY----TGATCELGIDEC--DPSPCKNGGSCTDLENSYSCTCPP 356
Query: 357 GL------VPSAAGAKPTCQDIDECADL------ISTIIMMSVDELQKSVDPQIPELCGA 404
G + + A C + C+D + S +K +D C
Sbjct: 357 GFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSN 416
Query: 405 GS-CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
G+ C + +++C+C G+S G C D+ D+C + C C + F C C
Sbjct: 417 GAKCVDLGDAYLCRCQAGFS-----GRHCDDNVDDC--ASSPCANGGTCRDGVNDFSCTC 469
Query: 463 RDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G+ G + V C + CH ATC + C C GY G
Sbjct: 470 PPGYTGRNCSAP-VSRC--EHAPCHNGATCHERGHRYVCECARGYGG 513
Score = 68.9 bits (161), Expect = 4e-11
Identities = 50/157 (31%), Positives = 68/157 (43%), Gaps = 24/157 (15%)
Query: 405 GSCHNTIGS-FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINL-PGSFQCRC 462
G H T + C C +G+ G C D C A C N GS+ C C
Sbjct: 262 GCLHGTCQQPWQCNCQEGWG-----GLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316
Query: 463 RDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
R G+ G ATCE +DEC + C +C + + S+ C C G+ G C
Sbjct: 317 RPGYTG--ATCELGIDEC--DPSPCKNGGSCTDLENSYSCTCPPGFYGK-------ICEL 365
Query: 522 SCVDIDECANDPTLCENGHCSNTP-GGYECDCDVGFT 557
S + CA+ P G CS++P GGY C C VG++
Sbjct: 366 SAMT---CADGPCF-NGGRCSDSPDGGYSCRCPVGYS 398
Score = 67.7 bits (158), Expect = 1e-10
Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++ ++EC P G G C +L ++C C PG+ C +++ DG C +G
Sbjct: 326 ELGIDECDPSPCKNG-GSCTDLENSYSCTCPPGFY----GKIC-ELSAMTCADGPCFNGG 379
Query: 176 -CHNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C ++ +G ++C C GY + K ID C+ + G +CV+ ++ C C G
Sbjct: 380 RCSDSPDGGYSCRCPVGYSGFNCEK---KIDYCSSSPC-SNGAKCVDLGDAYLCRCQAGF 435
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
R ++D+C+ S C+NG C + + + C C GY
Sbjct: 436 S---GRHCDDNVDDCA--SSPCANGGTCRDGVNDFSCTCPPGY 473
Score = 47.2 bits (107), Expect = 2e-04
Identities = 43/134 (32%), Positives = 61/134 (45%), Gaps = 29/134 (21%)
Query: 428 QGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCH 487
+GP CT+ C G + H D PG +C+CR GW+G C DEC+ G H
Sbjct: 217 KGPYCTEPI-CLPGCDEQHGFCD---KPG--ECKCRVGWQG--RYC---DECIRYPGCLH 265
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNT-P 545
TC ++C C G+ G ++ D++ C + C+NG C+NT
Sbjct: 266 --GTCQQP---WQCNCQEGWGG----------LFCNQDLNYCTHHKP-CKNGATCTNTGQ 309
Query: 546 GGYECDCDVGFTRA 559
G Y C C G+T A
Sbjct: 310 GSYTCSCRPGYTGA 323
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCH 177
V++CA+ P G G CR+ + F+C C PGY + + V+ CE C +G CH
Sbjct: 444 VDDCASSPCANG-GTCRDGVNDFSCTCPPGY---TGRNCSAPVSRCE--HAPCHNGATCH 497
Query: 178 NTEGSFTCHCRPGY 191
+ C C GY
Sbjct: 498 ERGHRYVCECARGY 511
>AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein.
Length = 723
Score = 98.7 bits (235), Expect = 5e-20
Identities = 77/243 (31%), Positives = 102/243 (41%), Gaps = 30/243 (12%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNT 179
+EC +PG C HG C+ + C+C G+ N D+N C C NT
Sbjct: 255 DECIRYPG-CLHGTCQQ---PWQCNCQEGWGGLFCNQ---DLNYCTHHKPCKNGATCTNT 307
Query: 180 -EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
+GS+TC CRPGY + IDEC D GG C + S+ C C G
Sbjct: 308 GQGSYTCSCRPGYTGATCE---LGIDEC-DPSPCKNGGSCTDLENSYSCTCPPGFYGKIC 363
Query: 239 RLSCKDIDECSITSGICSNGA-CENQM-GTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
LS C+ G C NG C + G Y C C GY+ +
Sbjct: 364 ELSAMT---CA--DGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGA 418
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCG-GGQCRNTVGSYTCTC 354
CV+ +Y C C+ G+ GR C D +D+CA PC GG CR+ V ++CTC
Sbjct: 419 ---KCVDLGDAYLCRCQAGF----SGRHCDDNVDDCASS--PCANGGTCRDGVNDFSCTC 469
Query: 355 TDG 357
G
Sbjct: 470 PPG 472
Score = 94.3 bits (224), Expect = 1e-18
Identities = 79/278 (28%), Positives = 112/278 (40%), Gaps = 45/278 (16%)
Query: 301 CVNTPGSYHCTCREGWHLRAD----GRSC-RDIDECAGGARPC-GGGQCRNT-VGSYTCT 353
C+ PG H TC++ W G C +D++ C +PC G C NT GSYTC+
Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHH-KPCKNGATCTNTGQGSYTCS 315
Query: 354 CTDGLVPSAAG-----AKPT-CQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
C G + P+ C++ C DL ++ + C G C
Sbjct: 316 CRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPC 375
Query: 408 HN-------TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQ 459
N G + C+CP GYS G C D C + C A C++L ++
Sbjct: 376 FNGGRCSDSPDGGYSCRCPVGYS-----GFNCEKKIDYCS--SSPCSNGAKCVDLGDAYL 428
Query: 460 CRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
CRC+ G+ G C+D VD+C ++ C TC + F C C GY G
Sbjct: 429 CRCQAGF--SGRHCDDNVDDCASS--PCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSR 484
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
C ++ C N T E GH GY C+C G+
Sbjct: 485 CEHA-----PCHNGATCHERGH------GYVCECARGY 511
Score = 83.8 bits (198), Expect = 1e-15
Identities = 92/347 (26%), Positives = 132/347 (38%), Gaps = 49/347 (14%)
Query: 187 CRPGYKADDFSKI-CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD- 244
CRP + D F C + E N +G C C+ HG P C+
Sbjct: 192 CRP--RDDAFGHFTCGERGEKVCNPGW-KGPYCTEPICLPGCDEQHGFCDKPGECKCRVG 248
Query: 245 -----IDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
DEC G C +G C+ +QC C EG+ + + +
Sbjct: 249 WQGRYCDECIRYPG-CLHGTCQQP---WQCNCQEGWGG--LFCNQDLNYCTHHKPCKNGA 302
Query: 300 SCVNT-PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTD 356
+C NT GSY C+CR G+ G +C IDEC PC GG C + SY+CTC
Sbjct: 303 TCTNTGQGSYTCSCRPGY----TGATCELGIDEC--DPSPCKNGGSCTDLENSYSCTCPP 356
Query: 357 GL------VPSAAGAKPTCQDIDECADL------ISTIIMMSVDELQKSVDPQIPELCGA 404
G + + A C + C+D + S +K +D C
Sbjct: 357 GFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSN 416
Query: 405 GS-CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
G+ C + +++C+C G+S G C D+ D+C + C C + F C C
Sbjct: 417 GAKCVDLGDAYLCRCQAGFS-----GRHCDDNVDDC--ASSPCANGGTCRDGVNDFSCTC 469
Query: 463 RDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G+ G + V C + CH ATC + C C GY G
Sbjct: 470 PPGYTGRNCSAP-VSRC--EHAPCHNGATCHERGHGYVCECARGYGG 513
Score = 68.9 bits (161), Expect = 4e-11
Identities = 50/157 (31%), Positives = 68/157 (43%), Gaps = 24/157 (15%)
Query: 405 GSCHNTIGS-FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINL-PGSFQCRC 462
G H T + C C +G+ G C D C A C N GS+ C C
Sbjct: 262 GCLHGTCQQPWQCNCQEGWG-----GLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316
Query: 463 RDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
R G+ G ATCE +DEC + C +C + + S+ C C G+ G C
Sbjct: 317 RPGYTG--ATCELGIDEC--DPSPCKNGGSCTDLENSYSCTCPPGFYGK-------ICEL 365
Query: 522 SCVDIDECANDPTLCENGHCSNTP-GGYECDCDVGFT 557
S + CA+ P G CS++P GGY C C VG++
Sbjct: 366 SAMT---CADGPCF-NGGRCSDSPDGGYSCRCPVGYS 398
Score = 67.7 bits (158), Expect = 1e-10
Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++ ++EC P G G C +L ++C C PG+ C +++ DG C +G
Sbjct: 326 ELGIDECDPSPCKNG-GSCTDLENSYSCTCPPGFY----GKIC-ELSAMTCADGPCFNGG 379
Query: 176 -CHNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C ++ +G ++C C GY + K ID C+ + G +CV+ ++ C C G
Sbjct: 380 RCSDSPDGGYSCRCPVGYSGFNCEK---KIDYCSSSPC-SNGAKCVDLGDAYLCRCQAGF 435
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
R ++D+C+ S C+NG C + + + C C GY
Sbjct: 436 S---GRHCDDNVDDCA--SSPCANGGTCRDGVNDFSCTCPPGY 473
Score = 47.2 bits (107), Expect = 2e-04
Identities = 43/134 (32%), Positives = 61/134 (45%), Gaps = 29/134 (21%)
Query: 428 QGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCH 487
+GP CT+ C G + H D PG +C+CR GW+G C DEC+ G H
Sbjct: 217 KGPYCTEPI-CLPGCDEQHGFCD---KPG--ECKCRVGWQG--RYC---DECIRYPGCLH 265
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNT-P 545
TC ++C C G+ G ++ D++ C + C+NG C+NT
Sbjct: 266 --GTCQQP---WQCNCQEGWGG----------LFCNQDLNYCTHHKP-CKNGATCTNTGQ 309
Query: 546 GGYECDCDVGFTRA 559
G Y C C G+T A
Sbjct: 310 GSYTCSCRPGYTGA 323
Score = 44.4 bits (100), Expect = 0.001
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCH 177
V++CA+ P G G CR+ + F+C C PGY + + V+ CE C +G CH
Sbjct: 444 VDDCASSPCANG-GTCRDGVNDFSCTCPPGY---TGRNCSAPVSRCE--HAPCHNGATCH 497
Query: 178 NTEGSFTCHCRPGY 191
+ C C GY
Sbjct: 498 ERGHGYVCECARGY 511
>AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein
protein.
Length = 723
Score = 98.7 bits (235), Expect = 5e-20
Identities = 77/243 (31%), Positives = 102/243 (41%), Gaps = 30/243 (12%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNT 179
+EC +PG C HG C+ + C+C G+ N D+N C C NT
Sbjct: 255 DECIRYPG-CLHGTCQQ---PWQCNCQEGWGGLFCNQ---DLNYCTHHKPCKNGATCTNT 307
Query: 180 -EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
+GS+TC CRPGY + IDEC D GG C + S+ C C G
Sbjct: 308 GQGSYTCSCRPGYTGATCE---LGIDEC-DPSPCKNGGSCTDLENSYSCTCPPGFYGKIC 363
Query: 239 RLSCKDIDECSITSGICSNGA-CENQM-GTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
LS C+ G C NG C + G Y C C GY+ +
Sbjct: 364 ELSAMT---CA--DGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGA 418
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCG-GGQCRNTVGSYTCTC 354
CV+ +Y C C+ G+ GR C D +D+CA PC GG CR+ V ++CTC
Sbjct: 419 ---KCVDLGDAYLCRCQAGF----SGRHCDDNVDDCASS--PCANGGTCRDGVNDFSCTC 469
Query: 355 TDG 357
G
Sbjct: 470 PPG 472
Score = 91.5 bits (217), Expect = 7e-18
Identities = 77/274 (28%), Positives = 110/274 (40%), Gaps = 45/274 (16%)
Query: 301 CVNTPGSYHCTCREGWHLRAD----GRSC-RDIDECAGGARPC-GGGQCRNT-VGSYTCT 353
C+ PG H TC++ W G C +D++ C +PC G C NT GSYTC+
Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHH-KPCKNGATCTNTGQGSYTCS 315
Query: 354 CTDGLVPSAAG-----AKPT-CQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
C G + P+ C++ C DL ++ + C G C
Sbjct: 316 CRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPC 375
Query: 408 HN-------TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQ 459
N G + C+CP GYS G C D C + C A C++L ++
Sbjct: 376 FNGGRCSDSPDGGYSCRCPVGYS-----GFNCEKKIDYCS--SSPCSNGAKCVDLGDAYL 428
Query: 460 CRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
CRC+ G+ G C+D VD+C ++ C TC + F C C GY G
Sbjct: 429 CRCQAGF--SGRHCDDNVDDCASS--PCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSR 484
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDC 552
C ++ C N T + GH GY C+C
Sbjct: 485 CEHA-----PCHNGATCHQRGH------GYVCEC 507
Score = 81.4 bits (192), Expect = 8e-15
Identities = 91/347 (26%), Positives = 131/347 (37%), Gaps = 49/347 (14%)
Query: 187 CRPGYKADDFSKI-CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD- 244
CRP + D F C + E N +G C C+ HG P C+
Sbjct: 192 CRP--RDDAFGHFTCGERGEKVCNPGW-KGPYCTEPICLPGCDEQHGFCDKPGECKCRVG 248
Query: 245 -----IDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
DEC G C +G C+ +QC C EG+ + + +
Sbjct: 249 WQGRYCDECIRYPG-CLHGTCQQP---WQCNCQEGWGG--LFCNQDLNYCTHHKPCKNGA 302
Query: 300 SCVNT-PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTD 356
+C NT GSY C+CR G+ G +C IDEC PC GG C + SY+CTC
Sbjct: 303 TCTNTGQGSYTCSCRPGY----TGATCELGIDEC--DPSPCKNGGSCTDLENSYSCTCPP 356
Query: 357 GL------VPSAAGAKPTCQDIDECADL------ISTIIMMSVDELQKSVDPQIPELCGA 404
G + + A C + C+D + S +K +D C
Sbjct: 357 GFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSN 416
Query: 405 GS-CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
G+ C + +++C+C G+S G C D+ D+C + C C + F C C
Sbjct: 417 GAKCVDLGDAYLCRCQAGFS-----GRHCDDNVDDC--ASSPCANGGTCRDGVNDFSCTC 469
Query: 463 RDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G+ G + V C + CH ATC + C C Y G
Sbjct: 470 PPGYTGRNCSAP-VSRC--EHAPCHNGATCHQRGHGYVCECARSYGG 513
Score = 68.9 bits (161), Expect = 4e-11
Identities = 50/157 (31%), Positives = 68/157 (43%), Gaps = 24/157 (15%)
Query: 405 GSCHNTIGS-FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINL-PGSFQCRC 462
G H T + C C +G+ G C D C A C N GS+ C C
Sbjct: 262 GCLHGTCQQPWQCNCQEGWG-----GLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316
Query: 463 RDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
R G+ G ATCE +DEC + C +C + + S+ C C G+ G C
Sbjct: 317 RPGYTG--ATCELGIDEC--DPSPCKNGGSCTDLENSYSCTCPPGFYGK-------ICEL 365
Query: 522 SCVDIDECANDPTLCENGHCSNTP-GGYECDCDVGFT 557
S + CA+ P G CS++P GGY C C VG++
Sbjct: 366 SAMT---CADGPCF-NGGRCSDSPDGGYSCRCPVGYS 398
Score = 67.7 bits (158), Expect = 1e-10
Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++ ++EC P G G C +L ++C C PG+ C +++ DG C +G
Sbjct: 326 ELGIDECDPSPCKNG-GSCTDLENSYSCTCPPGFY----GKIC-ELSAMTCADGPCFNGG 379
Query: 176 -CHNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C ++ +G ++C C GY + K ID C+ + G +CV+ ++ C C G
Sbjct: 380 RCSDSPDGGYSCRCPVGYSGFNCEK---KIDYCSSSPC-SNGAKCVDLGDAYLCRCQAGF 435
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
R ++D+C+ S C+NG C + + + C C GY
Sbjct: 436 S---GRHCDDNVDDCA--SSPCANGGTCRDGVNDFSCTCPPGY 473
Score = 47.6 bits (108), Expect = 1e-04
Identities = 49/160 (30%), Positives = 65/160 (40%), Gaps = 49/160 (30%)
Query: 428 QGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGD------------GATCED 475
+GP CT+ C G + H D PG +C+CR GW+G TC+
Sbjct: 217 KGPYCTEPI-CLPGCDEQHGFCD---KPG--ECKCRVGWQGRYCDECIRYPGCLHGTCQQ 270
Query: 476 VDEC-----------------LTNNGGCHPRATCANT-DGSFRCLCDTGYKGDGYGLRTV 517
+C T++ C ATC NT GS+ C C GY G
Sbjct: 271 PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG-------A 323
Query: 518 CCVYSCVDIDECANDPTLCEN-GHCSNTPGGYECDCDVGF 556
C + IDEC DP+ C+N G C++ Y C C GF
Sbjct: 324 TCE---LGIDEC--DPSPCKNGGSCTDLENSYSCTCPPGF 358
Score = 41.9 bits (94), Expect = 0.006
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCH 177
V++CA+ P G G CR+ + F+C C PGY + + V+ CE C +G CH
Sbjct: 444 VDDCASSPCANG-GTCRDGVNDFSCTCPPGY---TGRNCSAPVSRCE--HAPCHNGATCH 497
Query: 178 NTEGSFTCHCRPGY 191
+ C C Y
Sbjct: 498 QRGHGYVCECARSY 511
>AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein.
Length = 723
Score = 98.7 bits (235), Expect = 5e-20
Identities = 77/243 (31%), Positives = 102/243 (41%), Gaps = 30/243 (12%)
Query: 120 NECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGDCHNT 179
+EC +PG C HG C+ + C+C G+ N D+N C C NT
Sbjct: 255 DECIRYPG-CLHGTCQQ---PWQCNCQEGWGGLFCNQ---DLNYCTHHKPCKNGATCTNT 307
Query: 180 -EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPD 238
+GS+TC CRPGY + IDEC D GG C + S+ C C G
Sbjct: 308 GQGSYTCSCRPGYTGATCE---LGIDEC-DPSPCKNGGSCTDLENSYSCTCPPGFYGKIC 363
Query: 239 RLSCKDIDECSITSGICSNGA-CENQM-GTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXR 296
LS C+ G C NG C + G Y C C GY+ +
Sbjct: 364 ELSAMT---CA--DGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGA 418
Query: 297 CQHSCVNTPGSYHCTCREGWHLRADGRSCRD-IDECAGGARPCG-GGQCRNTVGSYTCTC 354
CV+ +Y C C+ G+ GR C D +D+CA PC GG CR+ V ++CTC
Sbjct: 419 ---KCVDLGDAYLCRCQAGF----SGRHCDDNVDDCASS--PCANGGTCRDGVNDFSCTC 469
Query: 355 TDG 357
G
Sbjct: 470 PPG 472
Score = 94.3 bits (224), Expect = 1e-18
Identities = 79/278 (28%), Positives = 112/278 (40%), Gaps = 45/278 (16%)
Query: 301 CVNTPGSYHCTCREGWHLRAD----GRSC-RDIDECAGGARPC-GGGQCRNT-VGSYTCT 353
C+ PG H TC++ W G C +D++ C +PC G C NT GSYTC+
Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHH-KPCKNGATCTNTGQGSYTCS 315
Query: 354 CTDGLVPSAAG-----AKPT-CQDIDECADLISTIIMMSVDELQKSVDPQIPELCGAGSC 407
C G + P+ C++ C DL ++ + C G C
Sbjct: 316 CRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPC 375
Query: 408 HN-------TIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQ 459
N G + C+CP GYS G C D C + C A C++L ++
Sbjct: 376 FNGGRCSDSPDGGYSCRCPVGYS-----GFNCEKKIDYCS--SSPCSNGAKCVDLGDAYL 428
Query: 460 CRCRDGWRGDGATCED-VDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVC 518
CRC+ G+ G C+D VD+C ++ C TC + F C C GY G
Sbjct: 429 CRCQAGF--SGRHCDDNVDDCASS--PCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSR 484
Query: 519 CVYSCVDIDECANDPTLCENGHCSNTPGGYECDCDVGF 556
C ++ C N T E GH GY C+C G+
Sbjct: 485 CEHA-----PCHNGATCHERGH------GYVCECARGY 511
Score = 83.8 bits (198), Expect = 1e-15
Identities = 92/347 (26%), Positives = 132/347 (38%), Gaps = 49/347 (14%)
Query: 187 CRPGYKADDFSKI-CVDIDECADNDALCRGGRCVNTAGSFRCECGHGMELAPDRLSCKD- 244
CRP + D F C + E N +G C C+ HG P C+
Sbjct: 192 CRP--RDDAFGHFTCGERGEKVCNPGW-KGPYCTEPICLPGCDEQHGFCDKPGECKCRVG 248
Query: 245 -----IDECSITSGICSNGACENQMGTYQCVCDEGYAQSTVKSHXXXXXXXXXXXXRCQH 299
DEC G C +G C+ +QC C EG+ + + +
Sbjct: 249 WQGRYCDECIRYPG-CLHGTCQQP---WQCNCQEGWGG--LFCNQDLNYCTHHKPCKNGA 302
Query: 300 SCVNT-PGSYHCTCREGWHLRADGRSCR-DIDECAGGARPC-GGGQCRNTVGSYTCTCTD 356
+C NT GSY C+CR G+ G +C IDEC PC GG C + SY+CTC
Sbjct: 303 TCTNTGQGSYTCSCRPGY----TGATCELGIDEC--DPSPCKNGGSCTDLENSYSCTCPP 356
Query: 357 GL------VPSAAGAKPTCQDIDECADL------ISTIIMMSVDELQKSVDPQIPELCGA 404
G + + A C + C+D + S +K +D C
Sbjct: 357 GFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSN 416
Query: 405 GS-CHNTIGSFVCQCPDGYSVKPEQGPACTDD-DECELGTCDCHPAADCINLPGSFQCRC 462
G+ C + +++C+C G+S G C D+ D+C + C C + F C C
Sbjct: 417 GAKCVDLGDAYLCRCQAGFS-----GRHCDDNVDDC--ASSPCANGGTCRDGVNDFSCTC 469
Query: 463 RDGWRGDGATCEDVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKG 509
G+ G + V C + CH ATC + C C GY G
Sbjct: 470 PPGYTGRNCSAP-VSRC--EHAPCHNGATCHERGHGYVCECARGYGG 513
Score = 68.9 bits (161), Expect = 4e-11
Identities = 50/157 (31%), Positives = 68/157 (43%), Gaps = 24/157 (15%)
Query: 405 GSCHNTIGS-FVCQCPDGYSVKPEQGPACTDDDECELGTCDCHPAADCINL-PGSFQCRC 462
G H T + C C +G+ G C D C A C N GS+ C C
Sbjct: 262 GCLHGTCQQPWQCNCQEGWG-----GLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316
Query: 463 RDGWRGDGATCE-DVDECLTNNGGCHPRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVY 521
R G+ G ATCE +DEC + C +C + + S+ C C G+ G C
Sbjct: 317 RPGYTG--ATCELGIDEC--DPSPCKNGGSCTDLENSYSCTCPPGFYGK-------ICEL 365
Query: 522 SCVDIDECANDPTLCENGHCSNTP-GGYECDCDVGFT 557
S + CA+ P G CS++P GGY C C VG++
Sbjct: 366 SAMT---CADGPCF-NGGRCSDSPDGGYSCRCPVGYS 398
Score = 67.7 bits (158), Expect = 1e-10
Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 116 QMEVNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDGD 175
++ ++EC P G G C +L ++C C PG+ C +++ DG C +G
Sbjct: 326 ELGIDECDPSPCKNG-GSCTDLENSYSCTCPPGFY----GKIC-ELSAMTCADGPCFNGG 379
Query: 176 -CHNT-EGSFTCHCRPGYKADDFSKICVDIDECADNDALCRGGRCVNTAGSFRCECGHGM 233
C ++ +G ++C C GY + K ID C+ + G +CV+ ++ C C G
Sbjct: 380 RCSDSPDGGYSCRCPVGYSGFNCEK---KIDYCSSSPC-SNGAKCVDLGDAYLCRCQAGF 435
Query: 234 ELAPDRLSCKDIDECSITSGICSNGA-CENQMGTYQCVCDEGY 275
R ++D+C+ S C+NG C + + + C C GY
Sbjct: 436 S---GRHCDDNVDDCA--SSPCANGGTCRDGVNDFSCTCPPGY 473
Score = 47.2 bits (107), Expect = 2e-04
Identities = 43/134 (32%), Positives = 61/134 (45%), Gaps = 29/134 (21%)
Query: 428 QGPACTDDDECELGTCDCHPAADCINLPGSFQCRCRDGWRGDGATCEDVDECLTNNGGCH 487
+GP CT+ C G + H D PG +C+CR GW+G C DEC+ G H
Sbjct: 217 KGPYCTEPI-CLPGCDEQHGFCD---KPG--ECKCRVGWQG--RYC---DECIRYPGCLH 265
Query: 488 PRATCANTDGSFRCLCDTGYKGDGYGLRTVCCVYSCVDIDECANDPTLCENGH-CSNT-P 545
TC ++C C G+ G ++ D++ C + C+NG C+NT
Sbjct: 266 --GTCQQP---WQCNCQEGWGG----------LFCNQDLNYCTHHKP-CKNGATCTNTGQ 309
Query: 546 GGYECDCDVGFTRA 559
G Y C C G+T A
Sbjct: 310 GSYTCSCRPGYTGA 323
Score = 44.4 bits (100), Expect = 0.001
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 119 VNECAAFPGLCGHGRCRNLLGGFTCDCFPGYEKDSKNHTCVDVNECEIVDGVCGDG-DCH 177
V++CA+ P G G CR+ + F+C C PGY + + V+ CE C +G CH
Sbjct: 444 VDDCASSPCANG-GTCRDGVNDFSCTCPPGY---TGRNCSAPVSRCE--HAPCHNGATCH 497
Query: 178 NTEGSFTCHCRPGY 191
+ C C GY
Sbjct: 498 ERGHGYVCECARGY 511
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.140 0.494
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,766,364
Number of Sequences: 224733
Number of extensions: 4996845
Number of successful extensions: 49149
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 622
Number of HSP's successfully gapped in prelim test: 478
Number of HSP's that attempted gapping in prelim test: 9914
Number of HSP's gapped (non-prelim): 12198
length of query: 568
length of database: 73,234,838
effective HSP length: 94
effective length of query: 474
effective length of database: 52,109,936
effective search space: 24700109664
effective search space used: 24700109664
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)
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