Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000206-TA|BGIBMGA000206-PA|IPR013091|EGF
calcium-binding, IPR002212|Matrix fibril-associated,
IPR006209|EGF-like, IPR009030|Growth factor, receptor,
IPR000152|Aspartic acid and asparagine hydroxylation site,
IPR013032|EGF-like region, IPR000742|EGF-like, type 3,
IPR001881|EGF-like calcium-binding, IPR006210|EGF
(453 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. 316 1e-85
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. 316 1e-85
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. 316 1e-85
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein. 316 1e-85
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ... 308 3e-83
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ... 308 3e-83
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ... 308 3e-83
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. 308 3e-83
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein. 308 3e-83
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein. 308 3e-83
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein. 308 3e-83
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein. 308 3e-83
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 300 6e-81
Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein. 273 1e-72
S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt... 273 1e-72
BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming gro... 273 1e-72
AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming gro... 273 1e-72
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital... 271 3e-72
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 259 2e-68
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 258 2e-68
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 258 2e-68
AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant pro... 257 7e-68
AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein. 249 1e-65
M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein. 248 2e-65
BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro... 248 2e-65
AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac... 248 2e-65
AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro... 248 2e-65
X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein. 237 8e-62
BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein. 237 8e-62
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein. 237 8e-62
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro... 237 8e-62
AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens ... 234 5e-61
AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein pr... 226 1e-58
X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein. 214 6e-55
AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming gro... 185 2e-46
X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein. 177 5e-44
BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein. 177 5e-44
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 177 9e-44
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 177 9e-44
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 176 2e-43
AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens ... 176 2e-43
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 176 2e-43
AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein. 175 3e-43
AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein. 175 4e-43
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 171 6e-42
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 168 3e-41
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 168 3e-41
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 168 3e-41
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 168 3e-41
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 168 3e-41
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 168 3e-41
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 168 3e-41
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 168 3e-41
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 168 3e-41
Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA seque... 164 7e-40
Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA seque... 164 7e-40
Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein. 163 1e-39
Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein. 163 1e-39
X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein. 163 1e-39
X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein. 163 1e-39
X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein. 163 1e-39
U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein. 163 1e-39
AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein. 163 1e-39
AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens ... 163 1e-39
AF525689-1|AAN77133.1| 988|Homo sapiens signal peptide-CUB-EGF-... 163 1e-39
AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein. 163 1e-39
AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D pre... 163 1e-39
BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein. 163 2e-39
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 159 2e-38
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 159 2e-38
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 159 2e-38
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 158 3e-38
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 157 1e-37
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 157 1e-37
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 157 1e-37
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 157 1e-37
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 157 1e-37
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant... 156 2e-37
Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA seque... 155 2e-37
BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein. 155 2e-37
AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and... 155 2e-37
AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing ... 155 2e-37
BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB dom... 154 5e-37
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 153 2e-36
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 153 2e-36
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 153 2e-36
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 153 2e-36
AF054501-1|AAC39881.1| 161|Homo sapiens latent transforming gro... 152 3e-36
U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor prot... 150 1e-35
BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein. 147 6e-35
BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein. 147 6e-35
AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein pr... 147 6e-35
X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein. 146 1e-34
AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein. 144 6e-34
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. 142 2e-33
CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein. 139 2e-32
BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing fibulin-... 139 2e-32
AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein. 139 2e-32
AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein. 139 2e-32
AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing fibulin-... 139 2e-32
AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding prot... 139 2e-32
AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellu... 136 1e-31
BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 136 2e-31
DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module contain... 136 2e-31
BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein. 136 2e-31
AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane hel... 136 2e-31
AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA seq... 134 5e-31
BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein. 133 1e-30
AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens ... 133 1e-30
AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein. 133 1e-30
AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens ... 133 1e-30
AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein. 133 1e-30
AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing fibulin-... 132 2e-30
U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein pro... 132 2e-30
BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing fibulin-... 132 2e-30
BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing fibulin-... 132 2e-30
AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing fibulin-... 132 2e-30
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. 130 1e-29
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 130 1e-29
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 130 1e-29
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 130 1e-29
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 130 1e-29
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 130 1e-29
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 130 1e-29
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 130 1e-29
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 130 1e-29
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. 130 1e-29
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 130 1e-29
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 128 4e-29
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 128 4e-29
D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 128 4e-29
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 128 4e-29
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 128 4e-29
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 128 4e-29
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 128 4e-29
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 128 4e-29
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 128 4e-29
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. 128 4e-29
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. 128 4e-29
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. 128 4e-29
CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein. 127 7e-29
BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein. 127 7e-29
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p... 127 7e-29
AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein. 127 7e-29
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 127 7e-29
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 127 7e-29
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 127 7e-29
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 127 7e-29
AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein. 127 7e-29
AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries ... 127 7e-29
D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein. 127 9e-29
D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2 pro... 127 9e-29
BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein. 127 9e-29
X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane ... 126 1e-28
U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein. 126 1e-28
BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module contain... 126 1e-28
BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module contain... 126 1e-28
AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module contain... 126 1e-28
AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2 pr... 126 1e-28
AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane hel... 126 1e-28
AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane hel... 126 1e-28
AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein. 125 3e-28
AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein. 125 4e-28
AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein. 124 6e-28
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. 124 9e-28
AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens ... 123 1e-27
AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. 119 2e-26
AK074499-1|BAC11024.1| 636|Homo sapiens protein ( Homo sapiens ... 118 3e-26
D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein. 118 4e-26
BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 118 4e-26
BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 118 4e-26
BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor p... 118 4e-26
AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS... 118 4e-26
U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein. 118 6e-26
BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein. 118 6e-26
AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1,... 118 6e-26
AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein pr... 118 6e-26
AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1,... 118 6e-26
L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific pr... 114 7e-25
BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific ... 114 7e-25
BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific ... 114 7e-25
AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specifi... 114 7e-25
AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens ... 114 7e-25
AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens ... 113 2e-24
AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens ... 113 2e-24
AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein. 112 2e-24
AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein. 111 6e-24
BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein. 110 1e-23
Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein. 106 1e-22
M57853-1|AAA60357.1| 676|Homo sapiens S protein protein. 106 1e-22
M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein. 106 1e-22
M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin K... 106 1e-22
BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein. 106 1e-22
AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein. 106 1e-22
X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA ... 104 7e-22
M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein. 104 7e-22
AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein pr... 103 1e-21
M16552-1|AAB59508.1| 575|Homo sapiens THBD protein. 103 1e-21
J02973-1|AAA61175.1| 575|Homo sapiens THBD protein. 103 1e-21
BC053357-1|AAH53357.1| 575|Homo sapiens thrombomodulin protein. 103 1e-21
AL049651-2|CAB51954.1| 575|Homo sapiens thrombomodulin protein. 103 1e-21
AF495471-1|AAM03232.1| 575|Homo sapiens thrombomodulin protein. 103 1e-21
X05495-1|CAA29045.1| 575|Homo sapiens thrombomodulin protein. 103 2e-21
D00210-1|BAA00149.1| 575|Homo sapiens thrombomodulin precursor ... 103 2e-21
BC053933-1|AAH53933.1| 239|Homo sapiens EMR2 protein protein. 103 2e-21
BC035602-1|AAH35602.2| 575|Homo sapiens thrombomodulin protein. 103 2e-21
BC034949-1|AAH34949.1| 239|Homo sapiens EMR2 protein protein. 103 2e-21
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 101 4e-21
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 101 4e-21
AB209121-1|BAD92358.1| 620|Homo sapiens Mutant p53 binding prot... 101 4e-21
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 101 5e-21
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 101 5e-21
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 101 5e-21
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 101 7e-21
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 101 7e-21
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 101 7e-21
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 101 7e-21
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 101 7e-21
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 101 7e-21
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ... 99 4e-20
U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein. 98 5e-20
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. 97 1e-19
U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homol... 96 2e-19
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs... 96 2e-19
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso... 96 2e-19
AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 96 2e-19
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 96 2e-19
AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 96 2e-19
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. 96 2e-19
X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein. 94 8e-19
M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein. 94 8e-19
M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein. 94 8e-19
AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein. 94 8e-19
AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein. 94 8e-19
AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. 94 8e-19
AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. 94 8e-19
AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. 94 1e-18
AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophil... 94 1e-18
AK027775-1|BAB55358.1| 537|Homo sapiens protein ( Homo sapiens ... 94 1e-18
AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) varia... 93 1e-18
BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multip... 93 2e-18
AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein. 93 2e-18
AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens ... 93 2e-18
AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein pr... 93 2e-18
AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor... 93 2e-18
AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein. 92 3e-18
BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein. 92 4e-18
BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein. 92 4e-18
BC133013-1|AAI33014.1| 594|Homo sapiens EGF-like-domain, multip... 91 6e-18
BC133011-1|AAI33012.1| 594|Homo sapiens EGF-like-domain, multip... 91 6e-18
BC077719-1|AAH77719.1| 219|Homo sapiens VWCE protein protein. 91 6e-18
BC052564-1|AAH52564.1| 219|Homo sapiens VWCE protein protein. 91 6e-18
BC042143-1|AAH42143.1| 237|Homo sapiens VWCE protein protein. 91 6e-18
AY358133-1|AAQ88500.1| 594|Homo sapiens TDKS9424 protein. 91 6e-18
AL589916-3|CAM13294.1| 594|Homo sapiens EGF-like-domain, multip... 91 6e-18
AL589916-2|CAI12363.2| 619|Homo sapiens EGF-like-domain, multip... 91 6e-18
AL365217-4|CAM23289.1| 594|Homo sapiens EGF-like-domain, multip... 91 6e-18
AL365217-3|CAI16606.1| 619|Homo sapiens EGF-like-domain, multip... 91 6e-18
AL132767-2|CAM28320.1| 594|Homo sapiens EGF-like-domain, multip... 91 6e-18
AL132767-1|CAI22904.1| 619|Homo sapiens EGF-like-domain, multip... 91 6e-18
AL109612-2|CAM27006.1| 594|Homo sapiens EGF-like-domain, multip... 91 6e-18
AL109612-1|CAI18881.1| 619|Homo sapiens EGF-like-domain, multip... 91 6e-18
AL021578-2|CAI21077.1| 432|Homo sapiens matrilin 4 protein. 91 6e-18
AL021578-1|CAB46380.1| 622|Homo sapiens matrilin 4 protein. 91 6e-18
AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isofor... 91 1e-17
BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein. 89 2e-17
AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein. 89 2e-17
AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF re... 89 2e-17
BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF re... 89 4e-17
AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 87 9e-17
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 87 9e-17
AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 87 9e-17
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt... 87 9e-17
S54426-1|AAB25244.1| 109|Homo sapiens fibrillin protein. 87 1e-16
BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 83 3e-15
BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophil... 83 3e-15
AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein. 83 3e-15
AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein. 83 3e-15
AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein. 83 3e-15
AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein. 83 3e-15
AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2 pr... 83 3e-15
BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 82 3e-15
AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 82 3e-15
AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 82 3e-15
D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein. 81 6e-15
BX640729-1|CAE45845.1| 674|Homo sapiens hypothetical protein pr... 81 6e-15
AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1 (Droso... 81 6e-15
AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein. 81 6e-15
AF193055-1|AAG22483.1| 474|Homo sapiens unknown protein. 81 6e-15
AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein. 81 6e-15
AK074396-1|BAB85069.1| 220|Homo sapiens protein ( Homo sapiens ... 81 8e-15
Y13341-1|CAA73785.1| 310|Homo sapiens matrilin-3 precursor prot... 81 1e-14
BC139907-1|AAI39908.1| 486|Homo sapiens matrilin 3 protein. 81 1e-14
BC060770-1|AAH60770.2| 757|Homo sapiens SUSD1 protein protein. 81 1e-14
AY358746-1|AAQ89106.1| 747|Homo sapiens GRGP2438 protein. 81 1e-14
AL158824-3|CAI12348.2| 705|Homo sapiens sushi domain containing... 81 1e-14
AL158824-2|CAI12347.2| 747|Homo sapiens sushi domain containing... 81 1e-14
AL138756-2|CAI95300.2| 705|Homo sapiens sushi domain containing... 81 1e-14
AL138756-1|CAI95299.2| 747|Homo sapiens sushi domain containing... 81 1e-14
AJ224741-1|CAA12110.1| 486|Homo sapiens matrilin-3 protein. 81 1e-14
AJ001047-1|CAA04501.1| 303|Homo sapiens Matrilin-3 protein. 81 1e-14
AC079145-2|AAX88937.1| 486|Homo sapiens unknown protein. 81 1e-14
BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. 80 2e-14
AC019195-1|AAY14953.1| 546|Homo sapiens unknown protein. 79 2e-14
BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein. 79 3e-14
BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophil... 79 3e-14
AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor ... 79 3e-14
BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. 79 4e-14
AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens ... 79 4e-14
AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens ... 77 1e-13
AC020594-1|AAY15036.1| 150|Homo sapiens unknown protein. 77 1e-13
M17778-1|AAA36799.1| 640|Homo sapiens protein ( Human uromoduli... 77 2e-13
M15881-1|AAA36798.1| 640|Homo sapiens protein ( Human uromoduli... 77 2e-13
BC035975-1|AAH35975.1| 611|Homo sapiens UMOD protein protein. 77 2e-13
AY162970-1|AAO64446.1| 640|Homo sapiens uromodulin precursor pr... 77 2e-13
BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein pr... 75 4e-13
BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosop... 75 4e-13
AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein. 75 4e-13
AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein. 75 4e-13
AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosop... 75 4e-13
AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB... 75 4e-13
AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein. 75 4e-13
X84700-1|CAA59173.1| 742|Homo sapiens leucocyte antigen CD97 pr... 75 5e-13
BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosop... 75 5e-13
BC026690-1|AAH26690.1| 742|Homo sapiens CD97 molecule protein. 75 5e-13
BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-termi... 75 5e-13
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 74 9e-13
X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for ... 74 1e-12
BC131763-1|AAI31764.1| 581|Homo sapiens matrilin 4 protein. 74 1e-12
BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor... 74 1e-12
BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor... 74 1e-12
AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal gro... 74 1e-12
AL021578-3|CAB39280.1| 581|Homo sapiens matrilin 4 protein. 74 1e-12
AJ007581-1|CAA07569.1| 581|Homo sapiens matrilin-4 protein. 74 1e-12
U15979-1|AAA75364.1| 382|Homo sapiens dlk protein. 72 4e-12
BC110320-1|AAI10321.1| 383|Homo sapiens EGF-like-domain, multip... 72 4e-12
AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein. 72 4e-12
AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosop... 72 4e-12
AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multip... 72 4e-12
AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multip... 72 4e-12
AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein. 71 8e-12
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 1e-11
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 71 1e-11
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 71 1e-11
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 1e-11
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 71 1e-11
BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein. 70 1e-11
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 70 1e-11
AB231861-1|BAE19679.1| 1950|Homo sapiens low-density lipoprotein... 70 1e-11
AB084910-1|BAD83615.1| 1905|Homo sapiens low density lipoprotein... 70 1e-11
X71923-1|CAA50739.1| 750|Homo sapiens tenascin-X precursor prot... 70 2e-11
U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein. 70 2e-11
DQ470680-1|ABF06672.1| 373|Homo sapiens CRELD2-zeta protein. 70 2e-11
DQ470679-1|ABF06671.1| 402|Homo sapiens CRELD2-epsilon protein. 70 2e-11
DQ470678-1|ABF06670.1| 353|Homo sapiens CRELD2-delta protein. 70 2e-11
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 70 2e-11
AY358355-1|AAQ88721.1| 353|Homo sapiens RLPR185 protein. 70 2e-11
AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein. 70 2e-11
AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein. 70 2e-11
AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein. 70 2e-11
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 70 2e-11
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 70 2e-11
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 70 2e-11
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. 69 3e-11
U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein. 69 3e-11
DQ309460-1|ABC26875.1| 231|Homo sapiens delta-like 1 protein. 69 3e-11
BC050675-1|AAH50675.1| 353|Homo sapiens cysteine-rich with EGF-... 69 3e-11
BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog (D... 69 3e-11
BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog (D... 69 3e-11
BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog (D... 69 3e-11
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 69 3e-11
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g... 69 3e-11
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g... 69 3e-11
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 69 3e-11
AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein. 69 3e-11
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 69 3e-11
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 69 5e-11
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 69 5e-11
AB011540-1|BAA32468.1| 1576|Homo sapiens MEGF7 protein. 69 5e-11
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 68 6e-11
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 68 6e-11
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 68 6e-11
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 68 6e-11
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 68 6e-11
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 68 6e-11
X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein. 68 8e-11
AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multip... 68 8e-11
AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachio... 68 8e-11
AB210038-1|BAE06120.1| 2233|Homo sapiens TNC variant protein pro... 68 8e-11
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec... 67 1e-10
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein... 67 1e-10
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re... 67 1e-10
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein... 67 1e-10
X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein. 66 2e-10
M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein. 66 2e-10
L32137-1|AAA57253.1| 757|Homo sapiens matrix protein protein. 66 2e-10
BC125092-1|AAI25093.1| 757|Homo sapiens cartilage oligomeric ma... 66 2e-10
BC110847-1|AAI10848.1| 757|Homo sapiens cartilage oligomeric ma... 66 2e-10
AC003107-1|AAB86501.1| 817|Homo sapiens COMP_HUMAN protein. 66 2e-10
AB086984-1|BAC53888.1| 757|Homo sapiens cartilage oligomeric ma... 66 2e-10
L00352-1|AAA56833.1| 860|Homo sapiens low density lipoprotein r... 66 3e-10
BT007361-1|AAP36025.1| 860|Homo sapiens low density lipoprotein... 66 3e-10
BC014514-1|AAH14514.1| 860|Homo sapiens low density lipoprotein... 66 3e-10
AY324609-1|AAP72971.1| 860|Homo sapiens low density lipoprotein... 66 3e-10
AY114155-1|AAM56036.1| 860|Homo sapiens low density lipoprotein... 66 3e-10
AF217403-1|AAF24515.1| 837|Homo sapiens low density lipoprotein... 66 3e-10
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 66 3e-10
AC093039-1|AAX88911.1| 425|Homo sapiens unknown protein. 66 3e-10
AB209409-1|BAD92646.1| 870|Homo sapiens low density lipoprotein... 66 3e-10
BC050456-1|AAH50456.1| 961|Homo sapiens thrombospondin 4 protein. 65 4e-10
BC038242-1|AAH38242.1| 261|Homo sapiens Similar to RIKEN cDNA 1... 65 4e-10
AY566253-1|AAS66982.1| 961|Homo sapiens thrombospondin 4 protein. 65 4e-10
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres... 65 4e-10
Z19585-1|CAA79635.1| 961|Homo sapiens thrombospondin-4 protein. 65 6e-10
AK223216-1|BAD96936.1| 757|Homo sapiens cartilage oligomeric ma... 64 7e-10
BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein. 64 1e-09
BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein. 64 1e-09
BC105633-1|AAI05634.1| 757|Homo sapiens tumor endothelial marke... 64 1e-09
BC104484-1|AAI04485.1| 757|Homo sapiens tumor endothelial marke... 64 1e-09
BC051340-1|AAH51340.1| 757|Homo sapiens CD248 molecule, endosia... 64 1e-09
AJ295846-1|CAC34381.1| 757|Homo sapiens endosialin protein prot... 64 1e-09
AF279142-1|AAG00867.1| 757|Homo sapiens tumor endothelial marke... 64 1e-09
AB058677-1|BAB47410.1| 969|Homo sapiens MEGF11 protein (KIAA178... 64 1e-09
D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein. 64 1e-09
DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein. 64 1e-09
AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein. 64 1e-09
AB052957-1|BAC15607.1| 803|Homo sapiens soluble form FELE-1 pro... 64 1e-09
AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein. 64 1e-09
AK126775-1|BAC86684.1| 952|Homo sapiens protein ( Homo sapiens ... 63 2e-09
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 63 2e-09
U15981-1|AAA75365.1| 310|Homo sapiens dlk protein. 63 2e-09
CR457380-1|CAG33661.1| 422|Homo sapiens CRELD1 protein. 62 3e-09
AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein pr... 62 3e-09
L38969-1|AAC41762.1| 956|Homo sapiens thrombospondin 3 protein. 62 5e-09
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. 62 5e-09
BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3, precu... 62 5e-09
AL713999-15|CAI95084.1| 956|Homo sapiens thrombospondin 3 protein. 62 5e-09
AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven... 62 5e-09
AK223278-1|BAD96998.1| 956|Homo sapiens thrombospondin 3 precur... 62 5e-09
AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein. 62 5e-09
AF023268-6|AAC51818.1| 736|Homo sapiens thrombospondin3 protein. 62 5e-09
AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel... 62 5e-09
AB024578-1|BAA88952.1| 78|Homo sapiens notch4 protein. 61 7e-09
X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F... 61 9e-09
BC008720-1|AAH08720.1| 422|Homo sapiens cysteine-rich with EGF-... 61 9e-09
AY358363-1|AAQ88729.1| 420|Homo sapiens CRELD1 protein. 61 9e-09
AF452623-1|AAM75206.1| 420|Homo sapiens cysteine-rich with EGF-... 61 9e-09
AY358347-1|AAQ88713.1| 406|Homo sapiens VPPP1921 protein. 60 2e-08
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 60 2e-08
AB075863-1|BAB85569.1| 418|Homo sapiens KIAA1983 protein protein. 60 2e-08
DQ470677-1|ABF06669.1| 325|Homo sapiens CRELD2-gamma protein. 60 2e-08
Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein... 59 3e-08
AY280362-1|AAP35084.1| 2386|Homo sapiens EGF domain-containing p... 59 3e-08
AB011541-1|BAA32469.2| 2785|Homo sapiens MEGF8 protein. 59 3e-08
AL606760-3|CAI18909.1| 700|Homo sapiens low density lipoprotein... 59 4e-08
AL355483-3|CAI22782.1| 700|Homo sapiens low density lipoprotein... 59 4e-08
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 59 4e-08
D86407-1|BAA21824.1| 963|Homo sapiens ApoER2 protein. 58 5e-08
D50678-1|BAA09328.1| 963|Homo sapiens apolipoprotein E receptor... 58 5e-08
DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein. 58 5e-08
DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein. 58 5e-08
BC051836-1|AAH51836.2| 904|Homo sapiens low density lipoprotein... 58 5e-08
AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein. 58 5e-08
AL606760-4|CAI18908.1| 963|Homo sapiens low density lipoprotein... 58 5e-08
AL606760-2|CAI18910.1| 904|Homo sapiens low density lipoprotein... 58 5e-08
AL355483-2|CAI22780.1| 904|Homo sapiens low density lipoprotein... 58 5e-08
AL355483-1|CAI22781.1| 963|Homo sapiens low density lipoprotein... 58 5e-08
AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo ... 58 5e-08
AB209912-1|BAD93149.1| 1225|Homo sapiens thrombospondin 1 precur... 58 5e-08
AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein. 58 5e-08
X14787-1|CAA32889.1| 1170|Homo sapiens precursor polypeptide (AA... 58 6e-08
X04665-1|CAA28370.1| 1170|Homo sapiens protein ( Human mRNA for ... 58 6e-08
AF283342-1|AAL38107.1| 881|Homo sapiens candidate tumor suppres... 58 6e-08
AC068287-1|AAY24318.1| 223|Homo sapiens unknown protein. 58 6e-08
S73849-1|AAB31735.1| 873|Homo sapiens very low density lipoprot... 58 8e-08
L22431-1|AAA61344.1| 873|Homo sapiens very low density lipoprot... 58 8e-08
D16532-1|BAA03969.1| 873|Homo sapiens very low density lipoprot... 58 8e-08
D16494-1|BAA03946.1| 845|Homo sapiens very low density lipoprot... 58 8e-08
D16493-1|BAA03945.1| 873|Homo sapiens very low density lipoprot... 58 8e-08
DQ067198-1|AAY46157.1| 873|Homo sapiens very low density lipopr... 58 8e-08
AL450467-4|CAH72455.1| 845|Homo sapiens very low density lipopr... 58 8e-08
AL450467-3|CAH72454.1| 873|Homo sapiens very low density lipopr... 58 8e-08
AL450467-2|CAH72453.1| 752|Homo sapiens very low density lipopr... 58 8e-08
AK092381-1|BAC03874.1| 752|Homo sapiens protein ( Homo sapiens ... 58 8e-08
AB208822-1|BAD92059.1| 555|Homo sapiens Very low-density lipopr... 58 8e-08
U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged pr... 57 1e-07
Z75190-1|CAA99509.1| 699|Homo sapiens apolipoprotein E receptor... 57 1e-07
DQ470676-1|ABF06668.1| 321|Homo sapiens CRELD2-alpha protein. 57 1e-07
BC126440-1|AAI26441.1| 321|Homo sapiens OIT3 protein protein. 57 1e-07
BC002894-1|AAH02894.1| 321|Homo sapiens CRELD2 protein protein. 57 1e-07
AY358339-1|AAQ88705.1| 545|Homo sapiens PPFL826 protein. 57 1e-07
AY013707-1|AAG40096.2| 545|Homo sapiens LZP protein. 57 1e-07
AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven... 57 1e-07
AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven... 57 1e-07
AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven... 57 1e-07
AK096435-1|BAC04788.1| 545|Homo sapiens protein ( Homo sapiens ... 57 1e-07
AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo ... 57 1e-07
D86407-2|BAA21825.1| 793|Homo sapiens ApoER2delta4-7 protein. 56 2e-07
DQ138965-1|AAZ66768.1| 203|Homo sapiens truncated brevideltinin... 56 3e-07
L20470-1|AAA53684.1| 873|Homo sapiens very low density lipoprot... 55 5e-07
>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
Length = 3002
Score = 316 bits (775), Expect = 1e-85
Identities = 176/479 (36%), Positives = 236/479 (49%), Gaps = 67/479 (13%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G C N G + C C+ GY+S CRD+DEC N R+C GRC NT GS+ C+C
Sbjct: 630 CAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCN 689
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF T G C D+DEC+ +MC G C+N +GSF+C+C+ G++ + C D++ECE
Sbjct: 690 AGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE 749
Query: 126 EQRVCRNG---------RCHNTPG-------------SFRCECLPGF-----------TL 152
+C NG RC PG R C G+ +
Sbjct: 750 TPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAV 809
Query: 153 SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS 212
+ C + +G CQ CPAQ S Y LC GP + G+DINEC P CP+G
Sbjct: 810 TKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGI 869
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
CENL Y+CIC+ GY D+ G C DI+EC ++ C GQCRNT GSF C CP+G +
Sbjct: 870 CENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIY 929
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR--CINTHGGFE 329
+P+L+ C DIDECE + + + P +F S D + CI T G
Sbjct: 930 KPDLKTCEDIDECESSPCINGVCK-----NSPGSFICECSSESTLDPTKTICIETIKG-T 983
Query: 330 CECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXX 389
C V+D RC N G+ + QC C S+G AWGS
Sbjct: 984 C---WQTVIDG---RCEININGA----TLKSQC-------------CSSLGAAWGS-PCT 1019
Query: 390 XXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
KG++++ G C D+DEC + +C G CVNT GS++C CP G+TLD+TG
Sbjct: 1020 LCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATG 1078
Score = 268 bits (658), Expect = 2e-71
Identities = 162/467 (34%), Positives = 219/467 (46%), Gaps = 55/467 (11%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG T C N +G +EC C+PG+ + C D+DEC DNP +C G+C N G Y
Sbjct: 1336 NGGCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYR 1393
Query: 63 CLCEPGF-APTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
CLC GF A C DV+EC + ++C G C N++GSF C C+ GY + C D
Sbjct: 1394 CLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTD 1453
Query: 121 VDECE--EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSCQACPA 175
++ECE ++ C NT GSF+C C PG+ DG C L G + Q
Sbjct: 1454 INECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADC 1511
Query: 176 QGSE-LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ + Y LC EG + D D++EC+ C +G C N GYRC CD G+ P AD
Sbjct: 1512 KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSAD 1571
Query: 234 G-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
G C DIDEC + + C G C N G F C C G + C D++EC
Sbjct: 1572 GKACEDIDECSL-PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-------- 1622
Query: 293 IESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGS 352
+ PT C +G C+NT G + C+C + L+ T C+D R G+
Sbjct: 1623 ---------LDPT---------TCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGN 1664
Query: 353 CW---RRVVDGQCEAAAPEL---LLRQECCCSVGLAWGSXXXXXXXXXXXXXK------- 399
C+ R D A + E+ + + CCCS+G AWG+ K
Sbjct: 1665 CYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGE 1724
Query: 400 GFAKLD-GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
GF D+DEC LC GG C+NT GS++C CP G L+
Sbjct: 1725 GFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLN 1771
Score = 256 bits (626), Expect = 2e-67
Identities = 164/472 (34%), Positives = 216/472 (45%), Gaps = 40/472 (8%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C NG+C N+ G F C C G+ + +C D+DEC++ P R C NTAGSY C
Sbjct: 1906 GVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCD 1965
Query: 65 CEPGFAPTAAGYCADVDEC-AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C+PG+ T+ G C D +EC ++C G+C+++ GSF C+C G++ + C+D++E
Sbjct: 1966 CKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINE 2025
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSC---QACPAQG 177
CE C NG C NT GSF C C GF LS++ C+ + G G C Q G
Sbjct: 2026 CERD-ACGNGTCRNTIGSFNCRCNHGFILSHN-NDCIDVDECASGNGNLCRNGQCINTVG 2083
Query: 178 SELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
S + C EG G DINEC P C G+C+NL+ YRCIC PGY +
Sbjct: 2084 S--FQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE- 2140
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI--DECEGETETHY 292
C DIDEC CA G C NT GSF C+CPEG + C+D+ C + E
Sbjct: 2141 KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGK 2200
Query: 293 IESDYERGDIPPTFPTRTE---LASPCDNGRC-INTHGGFECECELGYVL----DATA-- 342
S R + PC+ C F C G + D +A
Sbjct: 2201 CSSPKSRNHSKQECCCALKGEGWGDPCE--LCPTEPDEAFRQICPYGSGIIVGPDDSAVD 2258
Query: 343 -QRCLDN---RRGSCWRRVVDGQCEAAAPELLLRQECC----CSVGLAWGSXX--XXXXX 392
C + + G C +CE L EC CSVG G+
Sbjct: 2259 MDECKEPDVCKHGQCINTDGSYRCECPFGYTLAGNECVDTDECSVGNPCGNGTCKNVIGG 2318
Query: 393 XXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+GF TC D++ECA + LCA CVNT GSY C CP G L
Sbjct: 2319 FECTCEEGFEPGPMMTCEDINECAQNPLLCA-FRCVNTYGSYECKCPVGYVL 2369
Score = 250 bits (613), Expect = 6e-66
Identities = 158/489 (32%), Positives = 217/489 (44%), Gaps = 51/489 (10%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+CT+G C+N G F+C C G+ SE C D+DECR +P +C RG+C NT G + C C
Sbjct: 1169 LCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKC 1228
Query: 66 EPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+ G+ C D+DEC D +C+GG C N+EGS++C C G++ + AC+D++
Sbjct: 1229 DEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDIN 1288
Query: 123 ECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQG 177
ECE +C NGRC N G ++C C PG+ + D C+ + + G ++G
Sbjct: 1289 ECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEG 1348
Query: 178 SELYAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD- 233
S Y C G DI+EC P C G C N+ YRC+C G+ D
Sbjct: 1349 S--YECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDM 1406
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE---GETET 290
C D++ECD++ + C G C NT GSF C C G + C DI+ECE
Sbjct: 1407 KTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGK 1466
Query: 291 HYI----ESDYERGDIPPTFPTRTELA--SPCDNGR--------CINTHGGFECECELGY 336
H + ++ P + C NG C NT G + C C+ GY
Sbjct: 1467 HAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY 1526
Query: 337 VLD----ATAQRCLDN----RRGSCWRRVVDGQCE--------AAAPELLLRQECCCSVG 380
D C +N G C +CE A EC
Sbjct: 1527 TGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNI 1586
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
+G+ G+ +LD G C DV+EC L C G CVNT GSY CDC
Sbjct: 1587 CVFGTCHNLPGLFRCECEIGY-ELDRSGGNCTDVNEC-LDPTTCISGNCVNTPGSYICDC 1644
Query: 439 PPGLTLDST 447
PP L+ T
Sbjct: 1645 PPDFELNPT 1653
Score = 248 bits (607), Expect = 3e-65
Identities = 148/437 (33%), Positives = 211/437 (48%), Gaps = 45/437 (10%)
Query: 24 KPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADVDE 82
+PG+ L D+DECR+ P VC G C N GS+ C C G F C D+DE
Sbjct: 1883 RPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDE 1942
Query: 83 CAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPG 140
C +C + C+N+ GS++C C+ GYR T+T G C D +EC+E +C +G+C +T G
Sbjct: 1943 CQNGPVCQRNAECINTAGSYRCDCKPGYRFTST-GQCNDRNECQEIPNICSHGQCIDTVG 2001
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYAVLCPEG--PSKDNGGAD 197
SF C C GF ++D CL + +C + + + C G S +N D
Sbjct: 2002 SFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCID 2061
Query: 198 INECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCR 255
++EC + G C +G C N ++C C+ GY DG C DI+EC + CA G C+
Sbjct: 2062 VDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQ 2121
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N GS+ C+CP G + + + C DIDEC E E
Sbjct: 2122 NLDGSYRCICPPG--YSLQNEKCEDIDECVEEPEI------------------------- 2154
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C NT G F+C C G+ L ++ +RC D R C+ + G+C + +QEC
Sbjct: 2155 CALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQEC 2214
Query: 376 CCSV-GLAWGSXXXXXXXXXXXXXK-----GFAKLDGA--TCRDVDECALSAELCAGGTC 427
CC++ G WG + G + G + D+DEC ++C G C
Sbjct: 2215 CCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK-EPDVCKHGQC 2273
Query: 428 VNTDGSYRCDCPPGLTL 444
+NTDGSYRC+CP G TL
Sbjct: 2274 INTDGSYRCECPFGYTL 2290
Score = 227 bits (554), Expect = 8e-59
Identities = 148/472 (31%), Positives = 213/472 (45%), Gaps = 57/472 (12%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVC--RRGRCRNTAGSYTCLCEPGF 69
C N G +EC C GY + +C+D DEC + C ++ C+N G+Y C+C PG+
Sbjct: 2352 CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGY 2411
Query: 70 APTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE--CE 125
G C D +EC +C+ GRC+N+ GS+ C C G+ + + C+D E C
Sbjct: 2412 QRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCF 2471
Query: 126 E---QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
Q +C+ G + P + + EC + GR GWG C+ CP QG+ +
Sbjct: 2472 TEVLQNMCQIGSSNRNPVT-KSECC-----CDGGR-------GWGPHCEICPFQGTVAFK 2518
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDE 241
LCP G GADI+EC + C +G C N Y CIC GY PD G C D++E
Sbjct: 2519 KLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNE 2578
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET-HYIESDYERG 300
C+ C C+NT GS+ C CP+G + + + C+D+DEC + ++ + G
Sbjct: 2579 CNQAPKPC-NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGG 2637
Query: 301 ---DIPPTFPTR----------TELASPC-DNGRCINTHGGFECECELGYVLDATAQRCL 346
PP F T + C G C NT G F CEC+ G+ LD T C
Sbjct: 2638 FTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE 2697
Query: 347 D------NRRGSCWRRVVDGQCEAAAPELLLR----QEC-----CCSVGLAWG-SXXXXX 390
D N R + + G + P+ L+ +C C S + G S
Sbjct: 2698 DVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTL 2757
Query: 391 XXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF + C+D++EC + C+ G C NT+G Y C CPPG
Sbjct: 2758 GSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPG 2808
Score = 223 bits (544), Expect = 1e-57
Identities = 150/481 (31%), Positives = 211/481 (43%), Gaps = 60/481 (12%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G C+N+DG + CIC PGY +E C D+DEC + P +C G C NT GS+ CLC
Sbjct: 2115 CAPGTCQNLDGSYRCICPPGYSLQNEK--CEDIDECVEEPEICALGTCSNTEGSFKCLCP 2172
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVN----SEGSFQCVCEAGYRPTATRGACVDV 121
GF+ +++G C D+ + +GG+C + + +C C A +G
Sbjct: 2173 EGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC-------ALKGEGWG- 2224
Query: 122 DECEEQRVCRNGRCHNTPG-SFR--CECLPGFTLSNDGRTCLGLKLGWGVSC---QACPA 175
D CE C P +FR C G + D + C Q
Sbjct: 2225 DPCE--------LCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINT 2276
Query: 176 QGSELYAVLCPEGPS-KDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
GS Y CP G + N D +EC+ V C +G+C+N+ G+ C C+ G+ P
Sbjct: 2277 DGS--YRCECPFGYTLAGNECVDTDECS-VGNPCGNGTCKNVIGGFECTCEEGFEPGPMM 2333
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
C DI+EC + CA +C NT GS+ C CP G + ++C+D DECE E + E
Sbjct: 2334 TCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDECE-EGKHDCTE 2391
Query: 295 SDYERGDI--------PPTFPTRTE----------LASP--CDNGRCINTHGGFECECEL 334
E ++ P + R + P C+NGRC+NT G + CEC
Sbjct: 2392 KQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECND 2451
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPEL--LLRQECCCSVGLAWGSXXXXXXX 392
G+ CLDNR G C+ V+ C+ + + + ECCC G WG
Sbjct: 2452 GFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPF 2511
Query: 393 XXXXXXKGFAKLDG---ATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
K D+DEC + ++C G CVN GSY C C G T D TGT
Sbjct: 2512 QGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGT 2571
Query: 450 A 450
+
Sbjct: 2572 S 2572
Score = 220 bits (538), Expect = 7e-57
Identities = 142/423 (33%), Positives = 195/423 (46%), Gaps = 65/423 (15%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDEC-AADSMCKGGRC 94
+D++EC+ P +C G+CRNT GS+ C C+ GFA + C D+DEC + +C G+C
Sbjct: 1158 KDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQC 1217
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ G F+C C+ GY C+D+DEC+ + +CR G CHNT GS+RCEC PG L
Sbjct: 1218 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 1277
Query: 153 SNDGRTCLGLKLGWGVSCQACP-AQGSEL---YAVLCPEG--PSKDN-GGADINECTAVP 205
S + C+ + +S CP + L Y C G + D DI+EC+ +
Sbjct: 1278 SPNISACIDIN-ECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMN 1336
Query: 206 GACPHGSCENLEPGYRCICDPGY--HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
G C C N E Y C C PG+ PD C DIDEC+ + + C GGQC N G + C
Sbjct: 1337 GGC-ETFCTNSEGSYECSCQPGFALMPDQRS-CTDIDECEDNPNICDGGQCTNIPGEYRC 1394
Query: 264 VCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
+C +G +++ C D++EC D+ P C +G C N
Sbjct: 1395 LCYDGFMASEDMKTCVDVNEC----------------DLNPNI---------CLSGTCEN 1429
Query: 324 THGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAW 383
T G F C C++GY C D C + A +C CS G W
Sbjct: 1430 TKGSFICHCDMGYSGKKGKTGCTD--INECEIGAHNCGKHAVCTNTAGSFKCSCSPG--W 1485
Query: 384 GSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGL 442
DG C D+DEC+ +C+ C NT GSYRC C G
Sbjct: 1486 IG-------------------DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY 1526
Query: 443 TLD 445
T D
Sbjct: 1527 TGD 1529
Score = 214 bits (523), Expect = 5e-55
Identities = 154/463 (33%), Positives = 207/463 (44%), Gaps = 65/463 (14%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCLC 65
C NG C+N G F C C G+ S C DVDEC N +CR G+C NT GS+ C C
Sbjct: 2031 CGNGTCRNTIGSFNCRCNHGFIL-SHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQC 2089
Query: 66 EPGFAPTAAGY-CADVDECAADSM-CKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
G+ G C D++EC + C G C N +GS++C+C GY + C D+DE
Sbjct: 2090 NEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGY--SLQNEKCEDIDE 2147
Query: 124 C-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
C EE +C G C NT GSF+C C GF+LS+ GR C L++ + C A +G +
Sbjct: 2148 CVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSY---CYA-KFEGGK--- 2200
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCE--NLEP--GYRCICD--PGYHPDADGLC 236
C S+++ + C A+ G CE EP +R IC G D
Sbjct: 2201 --CSSPKSRNHSKQEC--CCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSA 2256
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE------GETET 290
D+DEC C GQC NT GS+ C CP G + C D DEC T
Sbjct: 2257 VDMDECK-EPDVCKHGQCINTDGSYRCECPFG--YTLAGNECVDTDECSVGNPCGNGTCK 2313
Query: 291 HYI---ESDYERGDIPPTFPTRTELASPCDNG-----RCINTHGGFECECELGYVLDATA 342
+ I E E G P T ++ N RC+NT+G +EC+C +GYVL
Sbjct: 2314 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDR 2373
Query: 343 QRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
+ C D + +CE + +Q EC +G G+
Sbjct: 2374 RMCKD-----------EDECEEGKHDCTEKQMECKNLIG-----------TYMCICGPGY 2411
Query: 402 AKL-DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+ DG C D +EC +C G C+NT GSY C+C G T
Sbjct: 2412 QRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFT 2454
Score = 208 bits (507), Expect = 4e-53
Identities = 143/454 (31%), Positives = 198/454 (43%), Gaps = 48/454 (10%)
Query: 6 MCT-NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
MC+ + CKN G + C+CK GY +G C D+DEC +N +C G+C N G Y C
Sbjct: 1504 MCSQHADCKNTMGSYRCLCKEGYTG--DGFTCTDLDECSENLNLCGNGQCLNAPGGYRCE 1561
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C+ GF P+A G C D+DEC+ ++C G C N G F+C CE GY + G C DV+E
Sbjct: 1562 CDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNE 1621
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG-WGVSCQACPAQGSELYA 182
C + C +G C NTPGS+ C+C P F L+ C+ + G + + G +
Sbjct: 1622 CLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACS 1681
Query: 183 VLCPEGPSKDNGGADINECTAVP-GACPHGSCENLEPGYRCICDPGYHPD-ADGLCRDID 240
G SK + + + P CP + E C G+ P+ + DID
Sbjct: 1682 NEIGVGVSKASCCCSLGKAWGTPCEMCP--AVNTSEYKILCPGGEGFRPNPITVILEDID 1739
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERG 300
EC C GG+C NT GSF C CP G + ++C D++EC ET I G
Sbjct: 1740 ECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC----ETPGICGP---G 1792
Query: 301 DIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDG 360
T T + P + +GG C +D C N D
Sbjct: 1793 TCYNTVGNYTCICPP----DYMQVNGGNNC-------MDMRRSLCYRN-------YYADN 1834
Query: 361 Q-CEAAAPELLLRQECCCS--VGLAWGS--------XXXXXXXXXXXXXKGFAKLDGATC 409
Q C+ + ++ CCCS +G AW GF +D T
Sbjct: 1835 QTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFV-IDIYTG 1893
Query: 410 RDV--DECALSAELCAGGTCVNTDGSYRCDCPPG 441
V DEC +C G C+N GS+RC+CP G
Sbjct: 1894 LPVDIDECREIPGVCENGVCINMVGSFRCECPVG 1927
Score = 205 bits (500), Expect = 3e-52
Identities = 141/427 (33%), Positives = 182/427 (42%), Gaps = 51/427 (11%)
Query: 40 DECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEG 99
D C+ +C+ GRC T GSY C C GF G C DVDEC + C GG C+N++G
Sbjct: 582 DYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNP-CAGGECINNQG 640
Query: 100 SFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
S+ C C AGY+ T TR C D+DEC + R+C NGRC NT GSF C C GF ++ DG+
Sbjct: 641 SYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 700
Query: 159 CLGLK----LGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHG 211
C + ++ GS + +C G + G DINEC PG C +G
Sbjct: 701 CEDMDECSIRNMCLNGMCINEDGS--FKCICKPGFQLASDGRYCKDINEC-ETPGICMNG 757
Query: 212 SCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-RNTAGSFT---CVCP 266
C N + YRC C PG DG +C D GQC + G+ T C C
Sbjct: 758 RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCA 817
Query: 267 EGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELA-SP--CDNGRCIN 323
E C + Y + E A P C NG C N
Sbjct: 818 -----STEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICEN 872
Query: 324 THGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPELLLRQECCCSVGLA 382
G ++C C GY +D+T + C+D + D GQC + C C G
Sbjct: 873 LRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFV----CTCPKGFI 928
Query: 383 WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGL 442
+ K D TC D+DEC S C G C N+ GS+ C+C
Sbjct: 929 Y-------------------KPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSSES 967
Query: 443 TLDSTGT 449
TLD T T
Sbjct: 968 TLDPTKT 974
Score = 202 bits (494), Expect = 2e-51
Identities = 105/288 (36%), Positives = 140/288 (48%), Gaps = 21/288 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NG +C NG C N G F+C C GYE +G C D++EC PR C G C+N GSY
Sbjct: 2069 NGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYR 2128
Query: 63 CLCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C+C PG++ C D+DEC + +C G C N+EGSF+C+C G+ +++ C D+
Sbjct: 2129 CICPPGYS-LQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDL 2187
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK-LGWGVSCQACPAQGSEL 180
R C+ +C P + C LK GWG C+ CP + E
Sbjct: 2188 ---------RMSYCYAKFEGGKCSS-PKSRNHSKQECCCALKGEGWGDPCELCPTEPDEA 2237
Query: 181 YAVLCPEGP----SKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ +CP G D+ D++EC P C HG C N + YRC C GY A C
Sbjct: 2238 FRQICPYGSGIIVGPDDSAVDMDECKE-PDVCKHGQCINTDGSYRCECPFGY-TLAGNEC 2295
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
D DEC + C G C+N G F C C EG P + C DI+EC
Sbjct: 2296 VDTDECSVGNP-CGNGTCKNVIGGFECTCEEGFEPGP-MMTCEDINEC 2341
Score = 192 bits (467), Expect = 3e-48
Identities = 146/487 (29%), Positives = 195/487 (40%), Gaps = 86/487 (17%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRD----------VD-ECRDNPR-VCRRGRC 54
C NG+CKN G F C C +C + +D C N + +C
Sbjct: 947 CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC 1006
Query: 55 RNTAGSY------TC----LCEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQC 103
++ G+ C +C G++ C D+DEC +CK G CVN+ GSF+C
Sbjct: 1007 CSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKC 1066
Query: 104 VCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C +G AT C+D+ R C C LP C +
Sbjct: 1067 QCPSGMTLDATGRICLDI---------RLETCFLRYEDEECT-LPIAGRHRMDACCCSVG 1116
Query: 164 LGWGVS-CQACPAQGSELYAVLCPEGP---SKD--NGG---ADINECTAVPGACPHGSCE 214
WG C+ CP + + Y LCP GP +K+ NG DINEC +P C HG C
Sbjct: 1117 AAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCR 1176
Query: 215 NLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE- 272
N ++C CD G+ D++ C DIDEC + C GQC NT G F C C EG
Sbjct: 1177 NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGF 1236
Query: 273 PELQLCRDIDECEGET------ETHYIESDYERGDIPPTFPTRTEL------------AS 314
++ C DIDEC+ + H E Y R + PP + A
Sbjct: 1237 MMMKNCMDIDECQRDPLLCRGGVCHNTEGSY-RCECPPGHQLSPNISACIDINECELSAH 1295
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NGRC+N G ++C C GY C+D S +++G CE E
Sbjct: 1296 LCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECS----IMNGGCETFCTNSEGSYE 1351
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSY 434
C C G A D +C D+DEC + +C GG C N G Y
Sbjct: 1352 CSCQPGFA-------------------LMPDQRSCTDIDECEDNPNICDGGQCTNIPGEY 1392
Query: 435 RCDCPPG 441
RC C G
Sbjct: 1393 RCLCYDG 1399
Score = 190 bits (463), Expect = 9e-48
Identities = 131/450 (29%), Positives = 189/450 (42%), Gaps = 64/450 (14%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
G+ + D+DEC++ P +C+ G+C NT GS+ C C G+ C DV+EC
Sbjct: 1725 GFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECE 1784
Query: 85 ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC-RNGRCHNTPGSFR 143
+C G C N+ G++ C+C Y C+D+ + +C RN N
Sbjct: 1785 TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM----RRSLCYRNYYADNQT---- 1836
Query: 144 CECLPGFTLSNDGRTCLGLKLG--WGVSCQACPAQGSELYAVLC-PEGPS-----KDNGG 195
C+ F ++ C +G W C+ CP ++ +A LC + P
Sbjct: 1837 CDGELLFNMTKK-MCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP 1895
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPG-YHPDADGLCRDIDECDMHQSYCAGGQC 254
DI+EC +PG C +G C N+ +RC C G ++ D +C DIDEC +C
Sbjct: 1896 VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC 1955
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NTAGS+ C C G R Q C D +EC+ E+ +
Sbjct: 1956 INTAGSYRCDCKPGYRFTSTGQ-CNDRNECQ-------------------------EIPN 1989
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNR--------RGSCWRRVVDGQCEAAA 366
C +G+CI+T G F C C G+ + CLD G+C + C
Sbjct: 1990 ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNH 2049
Query: 367 PELLLRQECC-----CSVG----LAWGSXXXXXXXXXXXXXKGF-AKLDGATCRDVDECA 416
+L C C+ G G +G+ DG TC D++EC
Sbjct: 2050 GFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECL 2109
Query: 417 LSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
L CA GTC N DGSYRC CPPG +L +
Sbjct: 2110 LEPRKCAPGTCQNLDGSYRCICPPGYSLQN 2139
Score = 186 bits (453), Expect = 1e-46
Identities = 95/271 (35%), Positives = 129/271 (47%), Gaps = 13/271 (4%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C NG C N GG+ C C G+ ++G C D+DEC P +C G C N G +
Sbjct: 1542 NLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDEC-SLPNICVFGTCHNLPGLFR 1600
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C CE G+ + G C DV+EC + C G CVN+ GS+ C C + TR CVD
Sbjct: 1601 CECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDT 1660
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
+ R G C G +S C L WG C+ CPA + Y
Sbjct: 1661 ---RSGNCYLDIRPRGDNGDTACSNEIGVGVSK-ASCCCSLGKAWGTPCEMCPAVNTSEY 1716
Query: 182 AVLCPEGPS-KDNGGA----DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-L 235
+LCP G + N DI+EC +PG C G C N ++C C GY+ + D +
Sbjct: 1717 KILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRV 1776
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCP 266
C D++EC+ C G C NT G++TC+CP
Sbjct: 1777 CDDVNECET-PGICGPGTCYNTVGNYTCICP 1806
Score = 180 bits (439), Expect = 7e-45
Identities = 132/448 (29%), Positives = 186/448 (41%), Gaps = 45/448 (10%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNS 97
D+DEC++ P VC+ G+C NT GSY C C G+ A C D DEC+ + C G C N
Sbjct: 2258 DMDECKE-PDVCKHGQCINTDGSYRCECPFGYT-LAGNECVDTDECSVGNPCGNGTCKNV 2315
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGR 157
G F+C CE G+ P C D++EC + + RC NT GS+ C+C G+ L D R
Sbjct: 2316 IGGFECTCEEGFEPGPMM-TCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRR 2374
Query: 158 TCLGL-KLGWGV-SCQACPAQGSEL---YAVLCPEGPSK---DNGGADINECTAVPGACP 209
C + G C + L Y +C G + G D NEC PG C
Sbjct: 2375 MCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICE 2434
Query: 210 HGSCENLEPGYRCICDPGY--HPDADGLCRDIDE--C--DMHQSYCA-GGQCRNTAGSFT 262
+G C N Y C C+ G+ P+ D C D E C ++ Q+ C G RN
Sbjct: 2435 NGRCLNTRGSYTCECNDGFTASPNQDE-CLDNREGYCFTEVLQNMCQIGSSNRNPVTKSE 2493
Query: 263 CVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP--PTFPTRTELASPCDNGR 320
C C G P ++C +G + + RG + + C NG
Sbjct: 2494 CCCDGGRGWGPHCEIC----PFQGTVAFKKL-CPHGRGFMTNGADIDECKVIHDVCRNGE 2548
Query: 321 CINTHGGFECECELGYVLDATAQRCLD-NRRGSCWR------RVVDGQCEAAAPELLLRQ 373
C+N G + C C+ GY D T C+D N + + +G + + P+ + Q
Sbjct: 2549 CVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQ 2608
Query: 374 E----------CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA 423
E C GF + +C D +EC LC
Sbjct: 2609 EDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQ-HHTSCIDNNECTSDINLCG 2667
Query: 424 G-GTCVNTDGSYRCDCPPGLTLDSTGTA 450
G C NT GS+ C+C G +LD TG++
Sbjct: 2668 SKGICQNTPGSFTCECQRGFSLDQTGSS 2695
Score = 179 bits (435), Expect = 2e-44
Identities = 101/271 (37%), Positives = 132/271 (48%), Gaps = 13/271 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C N G + CICK GY G C D++EC P+ C C+NT GSY C C
Sbjct: 2543 VCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSC 2601
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DECA CVN+ G F C C G+ T +C+D +EC
Sbjct: 2602 PKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGF--TQHHTSCIDNNEC 2659
Query: 125 -EEQRVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSELY 181
+ +C G C NTPGSF CEC GF+L G +C + + CQ Y
Sbjct: 2660 TSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGY 2719
Query: 182 AVLCPEGPSKD---NGGADINECTAVPGACPHGSCENLEPGYRCICDPGY-HPDADGLCR 237
CP+G + N D NEC + C SC N Y+C+C G+ + G C+
Sbjct: 2720 RCSCPQGYLQHYQWNQCVDENECLSA-HICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ 2778
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
DI+EC Q+ C+ G C NT G + C CP G
Sbjct: 2779 DINECGSAQAPCSYG-CSNTEGGYLCGCPPG 2808
Score = 176 bits (428), Expect = 2e-43
Identities = 129/415 (31%), Positives = 180/415 (43%), Gaps = 64/415 (15%)
Query: 49 CRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEA 107
C+ +N+A Y LC G T+AG +D++ECA D +C G C N G+++C+C +
Sbjct: 827 CQPCPAQNSA-EYQALCSSGPGMTSAG--SDINECALDPDICPNGICENLRGTYKCICNS 883
Query: 108 GYRPTATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW 166
GY +T CVD++EC +C NG+C NTPGSF C C GF D +TC +
Sbjct: 884 GYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID--- 940
Query: 167 GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPG--YRCI 223
C++ P C G K++ G+ I EC++ P + C G ++ +
Sbjct: 941 --ECESSP----------CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTV 988
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDE 283
D + +G +C G C T +C +G Q C DIDE
Sbjct: 989 IDGRCEININGATLK-SQCCSSLGAAWGSPC--TLCQVDPICGKGYSRIKGTQ-CEDIDE 1044
Query: 284 CEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQ 343
CE FP C NG C+NT G F+C+C G LDAT +
Sbjct: 1045 CE-------------------VFP------GVCKNGLCVNTRGSFKCQCPSGMTLDATGR 1079
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS--------XXXXXXXXXX 395
CLD R +C+ R D +C CCCSVG AWG+
Sbjct: 1080 ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELC 1139
Query: 396 XXXKGFAKLDGAT----CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
GFA + +D++EC + LC G C NT GS++C C G LDS
Sbjct: 1140 PRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDS 1194
Score = 165 bits (400), Expect = 4e-40
Identities = 130/450 (28%), Positives = 175/450 (38%), Gaps = 73/450 (16%)
Query: 6 MCTNGICKNIDGGFECICKPGYE-SGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTC 63
+C +G C N DG + C C GY +G+E C D DEC NP C G C+N G + C
Sbjct: 2267 VCKHGQCINTDGSYRCECPFGYTLAGNE---CVDTDECSVGNP--CGNGTCKNVIGGFEC 2321
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
CE GF P C D++ECA + + RCVN+ GS++C C GY R C D DE
Sbjct: 2322 TCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDE 2381
Query: 124 CEE-QRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
CEE + C + C N G++ C C PG+ DG C+ CQ P
Sbjct: 2382 CEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDEN-----ECQTKPG----- 2431
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDI 239
+C G + G+ EC A P+ C + GY C + +C+
Sbjct: 2432 ---ICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGY-CFTEV-----LQNMCQ-- 2480
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYER 299
G RN C C G P ++C +G + + R
Sbjct: 2481 ----------IGSSNRNPVTKSECCCDGGRGWGPHCEIC----PFQGTVAFKKL-CPHGR 2525
Query: 300 GDIP--PTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRV 357
G + + C NG C+N G + C C+ GY D T C+D C
Sbjct: 2526 GFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVD--LNEC--NQ 2581
Query: 358 VDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECAL 417
C +C C G + DG +C+D+DECA
Sbjct: 2582 APKPCNFICKNTEGSYQCSCPKGY-------------------ILQEDGRSCKDLDECAT 2622
Query: 418 SAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
C CVNT G + C CPPG T T
Sbjct: 2623 KQHNCQ-FLCVNTIGGFTCKCPPGFTQHHT 2651
Score = 165 bits (400), Expect = 4e-40
Identities = 92/239 (38%), Positives = 118/239 (49%), Gaps = 19/239 (7%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
N ICKN +G ++C C GY +G C+D+DEC C+ C NT G +TC C PG
Sbjct: 2587 NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF-LCVNTIGGFTCKCPPG 2645
Query: 69 FAPTAAGYCADVDECAAD-SMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
F C D +EC +D ++C G C N+ GSF C C+ G+ T +C DVDECE
Sbjct: 2646 FTQHHTS-CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEG 2704
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSN------DGRTCLGLKLGWGVSCQACPAQGSEL 180
C++G C N G +RC C G+ D CL + G SC GS
Sbjct: 2705 NHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHN--TLGS-- 2759
Query: 181 YAVLCPEGPSKD--NGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
Y +CP G + +GG DINEC + C +G C N E GY C C PGY G C
Sbjct: 2760 YKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGYFRIGQGHC 2817
Score = 163 bits (397), Expect = 9e-40
Identities = 134/455 (29%), Positives = 182/455 (40%), Gaps = 65/455 (14%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVD 81
C+ G+ C+DVDEC+ P +C+ G C NT GS+ C C G C D+D
Sbjct: 362 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 421
Query: 82 ECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN-TP 139
EC+ +C+GG C N+ S+ C C G+ + C+DV NGRC N P
Sbjct: 422 ECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLP 481
Query: 140 GSF-RCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC---------PEGP 189
S + +C D C G V+ + CP + +E + LC PE P
Sbjct: 482 QSITKMQC------CCDAGRC--WSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYP 533
Query: 190 SKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC 249
G I VP P G + P P D C + + C
Sbjct: 534 PPPLG--PIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLC 591
Query: 250 AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET----ETHYIESDYE---RGDI 302
G+C T GS+ C C +G + + + C D+DECE E + Y R
Sbjct: 592 QNGRCIPTPGSYRCECNKGFQLDLRGE-CIDVDECEKNPCAGGECINNQGSYTCQCRAGY 650
Query: 303 PPTFPTRTEL---------ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSC 353
T TRTE C+NGRCINT G F C C G+ + + C D S
Sbjct: 651 QSTL-TRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI 709
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVD 413
++G C +C C G S DG C+D++
Sbjct: 710 RNMCLNGMCINEDGSF----KCICKPGFQLAS-------------------DGRYCKDIN 746
Query: 414 ECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
EC + +C G CVNTDGSYRC+C PGL + G
Sbjct: 747 ECE-TPGICMNGRCVNTDGSYRCECFPGLAVGLDG 780
Score = 160 bits (388), Expect = 1e-38
Identities = 71/156 (45%), Positives = 89/156 (57%), Gaps = 5/156 (3%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C G + C C G++ G C DVDEC NP C G C N GSYTC C
Sbjct: 590 LCQNGRCIPTPGSYRCECNKGFQLDLRGE-CIDVDECEKNP--CAGGECINNQGSYTCQC 646
Query: 66 EPGFAPT-AAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
G+ T C D+DEC + +C GRC+N++GSF CVC AG+ T C D+DE
Sbjct: 647 RAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDE 706
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
C + +C NG C N GSF+C C PGF L++DGR C
Sbjct: 707 CSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC 742
Score = 129 bits (312), Expect = 2e-29
Identities = 61/162 (37%), Positives = 84/162 (51%), Gaps = 5/162 (3%)
Query: 8 TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEP 67
+ GIC+N G F C C+ G+ G+ C DVDEC N R C+ G C+N G Y C C
Sbjct: 2668 SKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQ 2725
Query: 68 GFAPTAA-GYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-E 125
G+ C D +EC + +C G C N+ GS++C+C AG++ G C D++EC
Sbjct: 2726 GYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGS 2785
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWG 167
Q C G C NT G + C C PG+ G G+ +G G
Sbjct: 2786 AQAPCSYG-CSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRG 2826
Score = 124 bits (298), Expect = 9e-28
Identities = 132/473 (27%), Positives = 173/473 (36%), Gaps = 69/473 (14%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C G C N+ G F C C+ GYE G C DV+EC D P C G C NT GSY C C
Sbjct: 1586 ICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTTCISGNCVNTPGSYICDC 1644
Query: 66 EPGFA--PTAAGYCADV--DECAADSMCKGGR----CVNSEG----SFQCVCEAGYRPTA 113
P F PT G C D C D +G C N G C C G
Sbjct: 1645 PPDFELNPTRVG-CVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGT 1703
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK-LGWGVSCQA 172
C V+ E + +C G FR P + D C L L G C
Sbjct: 1704 PCEMCPAVNTSEYKILCPGGE------GFRPN--PITVILEDIDECQELPGLCQGGKC-- 1753
Query: 173 CPAQGSELYAVLCPEGP--SKDNGGAD-INECTAVPGACPHGSCENLEPGYRCICDPGY- 228
GS + CP G ++D D +NEC PG C G+C N Y CIC P Y
Sbjct: 1754 INTFGS--FQCRCPTGYYLNEDTRVCDDVNECET-PGICGPGTCYNTVGNYTCICPPDYM 1810
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFT-----CVCPE--GTRHEPELQLCR-- 279
+ C D+ +++Y A Q + F C C G + C
Sbjct: 1811 QVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIP 1870
Query: 280 DIDECE---GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGY 336
DE G ++ Y +P E+ C+NG CIN G F CEC +G+
Sbjct: 1871 STDEFATLCGSQRPGFVIDIYT--GLPVDIDECREIPGVCENGVCINMVGSFRCECPVGF 1928
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
+ C D +D +C+ P EC + G
Sbjct: 1929 FYNDKLLVCED----------ID-ECQNG-PVCQRNAECINTAG-----------SYRCD 1965
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
G+ C D +EC +C+ G C++T GS+ C C G + T
Sbjct: 1966 CKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQT 2018
Score = 119 bits (287), Expect = 2e-26
Identities = 107/372 (28%), Positives = 141/372 (37%), Gaps = 64/372 (17%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT 72
N+ G + C PG+++ G C V CR + C G C C C G
Sbjct: 188 NVCGSRYNAYCCPGWKTLPGGNQCI-VPICRHS---CGDGFCSRPN---MCTCPSGQIAP 240
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
+ G + C M GG C + C+C+ GY T G V CE C N
Sbjct: 241 SCG-SRSIQHCNIRCM-NGGSCSDDH----CLCQKGYIGTHC-GQPV----CESG--CLN 287
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKD 192
G P RC C GFT R +S Q C Q L ++C +
Sbjct: 288 GGRCVAPN--RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQ---LSGIVCTK----- 337
Query: 193 NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA-DGLCRDIDECDMHQSYCAG 251
C A G CE + P C G+ P+ G C+D+DEC C G
Sbjct: 338 ------TLCCATVGRAWGHPCE-MCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQG 390
Query: 252 GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
G C NT GSF C CP G + Q C DIDEC T P
Sbjct: 391 GNCINTVGSFECKCPAGHKLNEVSQKCEDIDECS-------------------TIP---- 427
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLL 371
C+ G C NT + C+C G+ RC+D R G C+ + +G+C P+ +
Sbjct: 428 --GICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSIT 485
Query: 372 RQECCCSVGLAW 383
+ +CCC G W
Sbjct: 486 KMQCCCDAGRCW 497
Score = 111 bits (267), Expect = 5e-24
Identities = 92/330 (27%), Positives = 127/330 (38%), Gaps = 47/330 (14%)
Query: 1 MTNGGMCTNGICKNIDG-GF-----ECICKPGYESGSEGALCRDVDECRDNPRVCRRGRC 54
+ G C IC++ G GF C C G + S G+ R + C N R G C
Sbjct: 205 LPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGS--RSIQHC--NIRCMNGGSC 260
Query: 55 RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTA 113
+ CLC+ G+ T G + +S C GGRCV +C C G+
Sbjct: 261 SDDH----CLCQKGYIGTHCG------QPVCESGCLNGGRCVAPN---RCACTYGFTGP- 306
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQAC 173
+CE R R G C + C+ + C + WG C+ C
Sbjct: 307 ---------QCE--RDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMC 355
Query: 174 PAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH-PDA 232
PAQ P + D++EC A+PG C G+C N + C C G+ +
Sbjct: 356 PAQPHPCRRGFIPN--IRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEV 413
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C DIDEC C GG+C NT S+ C CP G P+ C D+ Y
Sbjct: 414 SQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV-------RPGY 466
Query: 293 IESDYERGDIPPTFP-TRTELASPCDNGRC 321
+ G P + T++ CD GRC
Sbjct: 467 CYTALTNGRCSNQLPQSITKMQCCCDAGRC 496
Score = 76.2 bits (179), Expect = 2e-13
Identities = 45/136 (33%), Positives = 63/136 (46%), Gaps = 11/136 (8%)
Query: 314 SPCDNG-RCINTHGGFECECELGYVLDATAQRC-LDNRRGSCWRRVVDGQCEAAAPELLL 371
S C NG RC+ + C C G+ T +C D R G C+ + + C+ ++
Sbjct: 283 SGCLNGGRCVAPN---RCACTYGF----TGPQCERDYRTGPCFTVISNQMCQGQLSGIVC 335
Query: 372 RQE-CCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVN 429
+ CC +VG AWG +GF + C+DVDEC LC GG C+N
Sbjct: 336 TKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCIN 395
Query: 430 TDGSYRCDCPPGLTLD 445
T GS+ C CP G L+
Sbjct: 396 TVGSFECKCPAGHKLN 411
Score = 53.2 bits (122), Expect = 2e-06
Identities = 20/41 (48%), Positives = 23/41 (56%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
C D+DEC+ +C GG C NT SY C CPPG GT
Sbjct: 417 CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGT 457
Score = 32.3 bits (70), Expect = 3.6
Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNP 46
C+ G C N +GG+ C C PGY +G + R NP
Sbjct: 2790 CSYG-CSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNP 2828
>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
Length = 2871
Score = 316 bits (775), Expect = 1e-85
Identities = 176/479 (36%), Positives = 236/479 (49%), Gaps = 67/479 (13%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G C N G + C C+ GY+S CRD+DEC N R+C GRC NT GS+ C+C
Sbjct: 499 CAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCN 558
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF T G C D+DEC+ +MC G C+N +GSF+C+C+ G++ + C D++ECE
Sbjct: 559 AGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE 618
Query: 126 EQRVCRNG---------RCHNTPG-------------SFRCECLPGF-----------TL 152
+C NG RC PG R C G+ +
Sbjct: 619 TPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAV 678
Query: 153 SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS 212
+ C + +G CQ CPAQ S Y LC GP + G+DINEC P CP+G
Sbjct: 679 TKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGI 738
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
CENL Y+CIC+ GY D+ G C DI+EC ++ C GQCRNT GSF C CP+G +
Sbjct: 739 CENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIY 798
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR--CINTHGGFE 329
+P+L+ C DIDECE + + + P +F S D + CI T G
Sbjct: 799 KPDLKTCEDIDECESSPCINGVCK-----NSPGSFICECSSESTLDPTKTICIETIKG-T 852
Query: 330 CECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXX 389
C V+D RC N G+ + QC C S+G AWGS
Sbjct: 853 C---WQTVIDG---RCEININGA----TLKSQC-------------CSSLGAAWGS-PCT 888
Query: 390 XXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
KG++++ G C D+DEC + +C G CVNT GS++C CP G+TLD+TG
Sbjct: 889 LCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATG 947
Score = 268 bits (658), Expect = 2e-71
Identities = 162/467 (34%), Positives = 219/467 (46%), Gaps = 55/467 (11%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG T C N +G +EC C+PG+ + C D+DEC DNP +C G+C N G Y
Sbjct: 1205 NGGCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYR 1262
Query: 63 CLCEPGF-APTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
CLC GF A C DV+EC + ++C G C N++GSF C C+ GY + C D
Sbjct: 1263 CLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTD 1322
Query: 121 VDECE--EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSCQACPA 175
++ECE ++ C NT GSF+C C PG+ DG C L G + Q
Sbjct: 1323 INECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADC 1380
Query: 176 QGSE-LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ + Y LC EG + D D++EC+ C +G C N GYRC CD G+ P AD
Sbjct: 1381 KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSAD 1440
Query: 234 G-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
G C DIDEC + + C G C N G F C C G + C D++EC
Sbjct: 1441 GKACEDIDECSL-PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-------- 1491
Query: 293 IESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGS 352
+ PT C +G C+NT G + C+C + L+ T C+D R G+
Sbjct: 1492 ---------LDPT---------TCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGN 1533
Query: 353 CW---RRVVDGQCEAAAPEL---LLRQECCCSVGLAWGSXXXXXXXXXXXXXK------- 399
C+ R D A + E+ + + CCCS+G AWG+ K
Sbjct: 1534 CYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGE 1593
Query: 400 GFAKLD-GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
GF D+DEC LC GG C+NT GS++C CP G L+
Sbjct: 1594 GFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLN 1640
Score = 256 bits (626), Expect = 2e-67
Identities = 164/472 (34%), Positives = 216/472 (45%), Gaps = 40/472 (8%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C NG+C N+ G F C C G+ + +C D+DEC++ P R C NTAGSY C
Sbjct: 1775 GVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCD 1834
Query: 65 CEPGFAPTAAGYCADVDEC-AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C+PG+ T+ G C D +EC ++C G+C+++ GSF C+C G++ + C+D++E
Sbjct: 1835 CKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINE 1894
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSC---QACPAQG 177
CE C NG C NT GSF C C GF LS++ C+ + G G C Q G
Sbjct: 1895 CERD-ACGNGTCRNTIGSFNCRCNHGFILSHN-NDCIDVDECASGNGNLCRNGQCINTVG 1952
Query: 178 SELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
S + C EG G DINEC P C G+C+NL+ YRCIC PGY +
Sbjct: 1953 S--FQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE- 2009
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI--DECEGETETHY 292
C DIDEC CA G C NT GSF C+CPEG + C+D+ C + E
Sbjct: 2010 KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGK 2069
Query: 293 IESDYERGDIPPTFPTRTE---LASPCDNGRC-INTHGGFECECELGYVL----DATA-- 342
S R + PC+ C F C G + D +A
Sbjct: 2070 CSSPKSRNHSKQECCCALKGEGWGDPCE--LCPTEPDEAFRQICPYGSGIIVGPDDSAVD 2127
Query: 343 -QRCLDN---RRGSCWRRVVDGQCEAAAPELLLRQECC----CSVGLAWGSXX--XXXXX 392
C + + G C +CE L EC CSVG G+
Sbjct: 2128 MDECKEPDVCKHGQCINTDGSYRCECPFGYTLAGNECVDTDECSVGNPCGNGTCKNVIGG 2187
Query: 393 XXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+GF TC D++ECA + LCA CVNT GSY C CP G L
Sbjct: 2188 FECTCEEGFEPGPMMTCEDINECAQNPLLCA-FRCVNTYGSYECKCPVGYVL 2238
Score = 250 bits (613), Expect = 6e-66
Identities = 158/489 (32%), Positives = 217/489 (44%), Gaps = 51/489 (10%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+CT+G C+N G F+C C G+ SE C D+DECR +P +C RG+C NT G + C C
Sbjct: 1038 LCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKC 1097
Query: 66 EPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+ G+ C D+DEC D +C+GG C N+EGS++C C G++ + AC+D++
Sbjct: 1098 DEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDIN 1157
Query: 123 ECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQG 177
ECE +C NGRC N G ++C C PG+ + D C+ + + G ++G
Sbjct: 1158 ECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEG 1217
Query: 178 SELYAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD- 233
S Y C G DI+EC P C G C N+ YRC+C G+ D
Sbjct: 1218 S--YECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDM 1275
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE---GETET 290
C D++ECD++ + C G C NT GSF C C G + C DI+ECE
Sbjct: 1276 KTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGK 1335
Query: 291 HYI----ESDYERGDIPPTFPTRTELA--SPCDNGR--------CINTHGGFECECELGY 336
H + ++ P + C NG C NT G + C C+ GY
Sbjct: 1336 HAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY 1395
Query: 337 VLD----ATAQRCLDN----RRGSCWRRVVDGQCE--------AAAPELLLRQECCCSVG 380
D C +N G C +CE A EC
Sbjct: 1396 TGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNI 1455
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
+G+ G+ +LD G C DV+EC L C G CVNT GSY CDC
Sbjct: 1456 CVFGTCHNLPGLFRCECEIGY-ELDRSGGNCTDVNEC-LDPTTCISGNCVNTPGSYICDC 1513
Query: 439 PPGLTLDST 447
PP L+ T
Sbjct: 1514 PPDFELNPT 1522
Score = 248 bits (607), Expect = 3e-65
Identities = 148/437 (33%), Positives = 211/437 (48%), Gaps = 45/437 (10%)
Query: 24 KPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADVDE 82
+PG+ L D+DECR+ P VC G C N GS+ C C G F C D+DE
Sbjct: 1752 RPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDE 1811
Query: 83 CAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPG 140
C +C + C+N+ GS++C C+ GYR T+T G C D +EC+E +C +G+C +T G
Sbjct: 1812 CQNGPVCQRNAECINTAGSYRCDCKPGYRFTST-GQCNDRNECQEIPNICSHGQCIDTVG 1870
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYAVLCPEG--PSKDNGGAD 197
SF C C GF ++D CL + +C + + + C G S +N D
Sbjct: 1871 SFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCID 1930
Query: 198 INECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCR 255
++EC + G C +G C N ++C C+ GY DG C DI+EC + CA G C+
Sbjct: 1931 VDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQ 1990
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N GS+ C+CP G + + + C DIDEC E E
Sbjct: 1991 NLDGSYRCICPPG--YSLQNEKCEDIDECVEEPEI------------------------- 2023
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C NT G F+C C G+ L ++ +RC D R C+ + G+C + +QEC
Sbjct: 2024 CALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQEC 2083
Query: 376 CCSV-GLAWGSXXXXXXXXXXXXXK-----GFAKLDGA--TCRDVDECALSAELCAGGTC 427
CC++ G WG + G + G + D+DEC ++C G C
Sbjct: 2084 CCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK-EPDVCKHGQC 2142
Query: 428 VNTDGSYRCDCPPGLTL 444
+NTDGSYRC+CP G TL
Sbjct: 2143 INTDGSYRCECPFGYTL 2159
Score = 227 bits (554), Expect = 8e-59
Identities = 148/472 (31%), Positives = 213/472 (45%), Gaps = 57/472 (12%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVC--RRGRCRNTAGSYTCLCEPGF 69
C N G +EC C GY + +C+D DEC + C ++ C+N G+Y C+C PG+
Sbjct: 2221 CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGY 2280
Query: 70 APTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE--CE 125
G C D +EC +C+ GRC+N+ GS+ C C G+ + + C+D E C
Sbjct: 2281 QRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCF 2340
Query: 126 E---QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
Q +C+ G + P + + EC + GR GWG C+ CP QG+ +
Sbjct: 2341 TEVLQNMCQIGSSNRNPVT-KSECC-----CDGGR-------GWGPHCEICPFQGTVAFK 2387
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDE 241
LCP G GADI+EC + C +G C N Y CIC GY PD G C D++E
Sbjct: 2388 KLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNE 2447
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET-HYIESDYERG 300
C+ C C+NT GS+ C CP+G + + + C+D+DEC + ++ + G
Sbjct: 2448 CNQAPKPC-NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGG 2506
Query: 301 ---DIPPTFPTR----------TELASPC-DNGRCINTHGGFECECELGYVLDATAQRCL 346
PP F T + C G C NT G F CEC+ G+ LD T C
Sbjct: 2507 FTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE 2566
Query: 347 D------NRRGSCWRRVVDGQCEAAAPELLLR----QEC-----CCSVGLAWG-SXXXXX 390
D N R + + G + P+ L+ +C C S + G S
Sbjct: 2567 DVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTL 2626
Query: 391 XXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF + C+D++EC + C+ G C NT+G Y C CPPG
Sbjct: 2627 GSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPG 2677
Score = 223 bits (544), Expect = 1e-57
Identities = 150/481 (31%), Positives = 211/481 (43%), Gaps = 60/481 (12%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G C+N+DG + CIC PGY +E C D+DEC + P +C G C NT GS+ CLC
Sbjct: 1984 CAPGTCQNLDGSYRCICPPGYSLQNEK--CEDIDECVEEPEICALGTCSNTEGSFKCLCP 2041
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVN----SEGSFQCVCEAGYRPTATRGACVDV 121
GF+ +++G C D+ + +GG+C + + +C C A +G
Sbjct: 2042 EGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC-------ALKGEGWG- 2093
Query: 122 DECEEQRVCRNGRCHNTPG-SFR--CECLPGFTLSNDGRTCLGLKLGWGVSC---QACPA 175
D CE C P +FR C G + D + C Q
Sbjct: 2094 DPCE--------LCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINT 2145
Query: 176 QGSELYAVLCPEGPS-KDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
GS Y CP G + N D +EC+ V C +G+C+N+ G+ C C+ G+ P
Sbjct: 2146 DGS--YRCECPFGYTLAGNECVDTDECS-VGNPCGNGTCKNVIGGFECTCEEGFEPGPMM 2202
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
C DI+EC + CA +C NT GS+ C CP G + ++C+D DECE E + E
Sbjct: 2203 TCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDECE-EGKHDCTE 2260
Query: 295 SDYERGDI--------PPTFPTRTE----------LASP--CDNGRCINTHGGFECECEL 334
E ++ P + R + P C+NGRC+NT G + CEC
Sbjct: 2261 KQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECND 2320
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPEL--LLRQECCCSVGLAWGSXXXXXXX 392
G+ CLDNR G C+ V+ C+ + + + ECCC G WG
Sbjct: 2321 GFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPF 2380
Query: 393 XXXXXXKGFAKLDG---ATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
K D+DEC + ++C G CVN GSY C C G T D TGT
Sbjct: 2381 QGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGT 2440
Query: 450 A 450
+
Sbjct: 2441 S 2441
Score = 220 bits (538), Expect = 7e-57
Identities = 142/423 (33%), Positives = 195/423 (46%), Gaps = 65/423 (15%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDEC-AADSMCKGGRC 94
+D++EC+ P +C G+CRNT GS+ C C+ GFA + C D+DEC + +C G+C
Sbjct: 1027 KDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQC 1086
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ G F+C C+ GY C+D+DEC+ + +CR G CHNT GS+RCEC PG L
Sbjct: 1087 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 1146
Query: 153 SNDGRTCLGLKLGWGVSCQACP-AQGSEL---YAVLCPEG--PSKDN-GGADINECTAVP 205
S + C+ + +S CP + L Y C G + D DI+EC+ +
Sbjct: 1147 SPNISACIDIN-ECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMN 1205
Query: 206 GACPHGSCENLEPGYRCICDPGY--HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
G C C N E Y C C PG+ PD C DIDEC+ + + C GGQC N G + C
Sbjct: 1206 GGC-ETFCTNSEGSYECSCQPGFALMPDQRS-CTDIDECEDNPNICDGGQCTNIPGEYRC 1263
Query: 264 VCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
+C +G +++ C D++EC D+ P C +G C N
Sbjct: 1264 LCYDGFMASEDMKTCVDVNEC----------------DLNPNI---------CLSGTCEN 1298
Query: 324 THGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAW 383
T G F C C++GY C D C + A +C CS G W
Sbjct: 1299 TKGSFICHCDMGYSGKKGKTGCTD--INECEIGAHNCGKHAVCTNTAGSFKCSCSPG--W 1354
Query: 384 GSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGL 442
DG C D+DEC+ +C+ C NT GSYRC C G
Sbjct: 1355 IG-------------------DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY 1395
Query: 443 TLD 445
T D
Sbjct: 1396 TGD 1398
Score = 214 bits (523), Expect = 5e-55
Identities = 154/463 (33%), Positives = 207/463 (44%), Gaps = 65/463 (14%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCLC 65
C NG C+N G F C C G+ S C DVDEC N +CR G+C NT GS+ C C
Sbjct: 1900 CGNGTCRNTIGSFNCRCNHGFIL-SHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQC 1958
Query: 66 EPGFAPTAAGY-CADVDECAADSM-CKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
G+ G C D++EC + C G C N +GS++C+C GY + C D+DE
Sbjct: 1959 NEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGY--SLQNEKCEDIDE 2016
Query: 124 C-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
C EE +C G C NT GSF+C C GF+LS+ GR C L++ + C A +G +
Sbjct: 2017 CVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSY---CYA-KFEGGK--- 2069
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCE--NLEP--GYRCICD--PGYHPDADGLC 236
C S+++ + C A+ G CE EP +R IC G D
Sbjct: 2070 --CSSPKSRNHSKQEC--CCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSA 2125
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE------GETET 290
D+DEC C GQC NT GS+ C CP G + C D DEC T
Sbjct: 2126 VDMDECK-EPDVCKHGQCINTDGSYRCECPFG--YTLAGNECVDTDECSVGNPCGNGTCK 2182
Query: 291 HYI---ESDYERGDIPPTFPTRTELASPCDNG-----RCINTHGGFECECELGYVLDATA 342
+ I E E G P T ++ N RC+NT+G +EC+C +GYVL
Sbjct: 2183 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDR 2242
Query: 343 QRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
+ C D + +CE + +Q EC +G G+
Sbjct: 2243 RMCKD-----------EDECEEGKHDCTEKQMECKNLIG-----------TYMCICGPGY 2280
Query: 402 AKL-DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+ DG C D +EC +C G C+NT GSY C+C G T
Sbjct: 2281 QRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFT 2323
Score = 208 bits (507), Expect = 4e-53
Identities = 143/454 (31%), Positives = 198/454 (43%), Gaps = 48/454 (10%)
Query: 6 MCT-NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
MC+ + CKN G + C+CK GY +G C D+DEC +N +C G+C N G Y C
Sbjct: 1373 MCSQHADCKNTMGSYRCLCKEGYTG--DGFTCTDLDECSENLNLCGNGQCLNAPGGYRCE 1430
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C+ GF P+A G C D+DEC+ ++C G C N G F+C CE GY + G C DV+E
Sbjct: 1431 CDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNE 1490
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG-WGVSCQACPAQGSELYA 182
C + C +G C NTPGS+ C+C P F L+ C+ + G + + G +
Sbjct: 1491 CLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACS 1550
Query: 183 VLCPEGPSKDNGGADINECTAVP-GACPHGSCENLEPGYRCICDPGYHPD-ADGLCRDID 240
G SK + + + P CP + E C G+ P+ + DID
Sbjct: 1551 NEIGVGVSKASCCCSLGKAWGTPCEMCP--AVNTSEYKILCPGGEGFRPNPITVILEDID 1608
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERG 300
EC C GG+C NT GSF C CP G + ++C D++EC ET I G
Sbjct: 1609 ECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC----ETPGICGP---G 1661
Query: 301 DIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDG 360
T T + P + +GG C +D C N D
Sbjct: 1662 TCYNTVGNYTCICPP----DYMQVNGGNNC-------MDMRRSLCYRN-------YYADN 1703
Query: 361 Q-CEAAAPELLLRQECCCS--VGLAWGS--------XXXXXXXXXXXXXKGFAKLDGATC 409
Q C+ + ++ CCCS +G AW GF +D T
Sbjct: 1704 QTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFV-IDIYTG 1762
Query: 410 RDV--DECALSAELCAGGTCVNTDGSYRCDCPPG 441
V DEC +C G C+N GS+RC+CP G
Sbjct: 1763 LPVDIDECREIPGVCENGVCINMVGSFRCECPVG 1796
Score = 205 bits (500), Expect = 3e-52
Identities = 141/427 (33%), Positives = 182/427 (42%), Gaps = 51/427 (11%)
Query: 40 DECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEG 99
D C+ +C+ GRC T GSY C C GF G C DVDEC + C GG C+N++G
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNP-CAGGECINNQG 509
Query: 100 SFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
S+ C C AGY+ T TR C D+DEC + R+C NGRC NT GSF C C GF ++ DG+
Sbjct: 510 SYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 569
Query: 159 CLGLK----LGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHG 211
C + ++ GS + +C G + G DINEC PG C +G
Sbjct: 570 CEDMDECSIRNMCLNGMCINEDGS--FKCICKPGFQLASDGRYCKDINEC-ETPGICMNG 626
Query: 212 SCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-RNTAGSFT---CVCP 266
C N + YRC C PG DG +C D GQC + G+ T C C
Sbjct: 627 RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCA 686
Query: 267 EGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELA-SP--CDNGRCIN 323
E C + Y + E A P C NG C N
Sbjct: 687 -----STEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICEN 741
Query: 324 THGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPELLLRQECCCSVGLA 382
G ++C C GY +D+T + C+D + D GQC + C C G
Sbjct: 742 LRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFV----CTCPKGFI 797
Query: 383 WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGL 442
+ K D TC D+DEC S C G C N+ GS+ C+C
Sbjct: 798 Y-------------------KPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSSES 836
Query: 443 TLDSTGT 449
TLD T T
Sbjct: 837 TLDPTKT 843
Score = 202 bits (494), Expect = 2e-51
Identities = 105/288 (36%), Positives = 140/288 (48%), Gaps = 21/288 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NG +C NG C N G F+C C GYE +G C D++EC PR C G C+N GSY
Sbjct: 1938 NGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYR 1997
Query: 63 CLCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C+C PG++ C D+DEC + +C G C N+EGSF+C+C G+ +++ C D+
Sbjct: 1998 CICPPGYS-LQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDL 2056
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK-LGWGVSCQACPAQGSEL 180
R C+ +C P + C LK GWG C+ CP + E
Sbjct: 2057 ---------RMSYCYAKFEGGKCSS-PKSRNHSKQECCCALKGEGWGDPCELCPTEPDEA 2106
Query: 181 YAVLCPEGP----SKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ +CP G D+ D++EC P C HG C N + YRC C GY A C
Sbjct: 2107 FRQICPYGSGIIVGPDDSAVDMDECKE-PDVCKHGQCINTDGSYRCECPFGY-TLAGNEC 2164
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
D DEC + C G C+N G F C C EG P + C DI+EC
Sbjct: 2165 VDTDECSVGNP-CGNGTCKNVIGGFECTCEEGFEPGP-MMTCEDINEC 2210
Score = 192 bits (467), Expect = 3e-48
Identities = 146/487 (29%), Positives = 195/487 (40%), Gaps = 86/487 (17%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRD----------VD-ECRDNPR-VCRRGRC 54
C NG+CKN G F C C +C + +D C N + +C
Sbjct: 816 CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC 875
Query: 55 RNTAGSY------TC----LCEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQC 103
++ G+ C +C G++ C D+DEC +CK G CVN+ GSF+C
Sbjct: 876 CSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKC 935
Query: 104 VCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C +G AT C+D+ R C C LP C +
Sbjct: 936 QCPSGMTLDATGRICLDI---------RLETCFLRYEDEECT-LPIAGRHRMDACCCSVG 985
Query: 164 LGWGVS-CQACPAQGSELYAVLCPEGP---SKD--NGG---ADINECTAVPGACPHGSCE 214
WG C+ CP + + Y LCP GP +K+ NG DINEC +P C HG C
Sbjct: 986 AAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCR 1045
Query: 215 NLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE- 272
N ++C CD G+ D++ C DIDEC + C GQC NT G F C C EG
Sbjct: 1046 NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGF 1105
Query: 273 PELQLCRDIDECEGET------ETHYIESDYERGDIPPTFPTRTEL------------AS 314
++ C DIDEC+ + H E Y R + PP + A
Sbjct: 1106 MMMKNCMDIDECQRDPLLCRGGVCHNTEGSY-RCECPPGHQLSPNISACIDINECELSAH 1164
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NGRC+N G ++C C GY C+D S +++G CE E
Sbjct: 1165 LCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECS----IMNGGCETFCTNSEGSYE 1220
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSY 434
C C G A D +C D+DEC + +C GG C N G Y
Sbjct: 1221 CSCQPGFA-------------------LMPDQRSCTDIDECEDNPNICDGGQCTNIPGEY 1261
Query: 435 RCDCPPG 441
RC C G
Sbjct: 1262 RCLCYDG 1268
Score = 190 bits (463), Expect = 9e-48
Identities = 131/450 (29%), Positives = 189/450 (42%), Gaps = 64/450 (14%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
G+ + D+DEC++ P +C+ G+C NT GS+ C C G+ C DV+EC
Sbjct: 1594 GFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECE 1653
Query: 85 ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC-RNGRCHNTPGSFR 143
+C G C N+ G++ C+C Y C+D+ + +C RN N
Sbjct: 1654 TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM----RRSLCYRNYYADNQT---- 1705
Query: 144 CECLPGFTLSNDGRTCLGLKLG--WGVSCQACPAQGSELYAVLC-PEGPS-----KDNGG 195
C+ F ++ C +G W C+ CP ++ +A LC + P
Sbjct: 1706 CDGELLFNMTKK-MCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP 1764
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPG-YHPDADGLCRDIDECDMHQSYCAGGQC 254
DI+EC +PG C +G C N+ +RC C G ++ D +C DIDEC +C
Sbjct: 1765 VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC 1824
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NTAGS+ C C G R Q C D +EC+ E+ +
Sbjct: 1825 INTAGSYRCDCKPGYRFTSTGQ-CNDRNECQ-------------------------EIPN 1858
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNR--------RGSCWRRVVDGQCEAAA 366
C +G+CI+T G F C C G+ + CLD G+C + C
Sbjct: 1859 ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNH 1918
Query: 367 PELLLRQECC-----CSVG----LAWGSXXXXXXXXXXXXXKGF-AKLDGATCRDVDECA 416
+L C C+ G G +G+ DG TC D++EC
Sbjct: 1919 GFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECL 1978
Query: 417 LSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
L CA GTC N DGSYRC CPPG +L +
Sbjct: 1979 LEPRKCAPGTCQNLDGSYRCICPPGYSLQN 2008
Score = 186 bits (453), Expect = 1e-46
Identities = 95/271 (35%), Positives = 129/271 (47%), Gaps = 13/271 (4%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C NG C N GG+ C C G+ ++G C D+DEC P +C G C N G +
Sbjct: 1411 NLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDEC-SLPNICVFGTCHNLPGLFR 1469
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C CE G+ + G C DV+EC + C G CVN+ GS+ C C + TR CVD
Sbjct: 1470 CECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDT 1529
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
+ R G C G +S C L WG C+ CPA + Y
Sbjct: 1530 ---RSGNCYLDIRPRGDNGDTACSNEIGVGVSK-ASCCCSLGKAWGTPCEMCPAVNTSEY 1585
Query: 182 AVLCPEGPS-KDNGGA----DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-L 235
+LCP G + N DI+EC +PG C G C N ++C C GY+ + D +
Sbjct: 1586 KILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRV 1645
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCP 266
C D++EC+ C G C NT G++TC+CP
Sbjct: 1646 CDDVNECET-PGICGPGTCYNTVGNYTCICP 1675
Score = 180 bits (439), Expect = 7e-45
Identities = 132/448 (29%), Positives = 186/448 (41%), Gaps = 45/448 (10%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNS 97
D+DEC++ P VC+ G+C NT GSY C C G+ A C D DEC+ + C G C N
Sbjct: 2127 DMDECKE-PDVCKHGQCINTDGSYRCECPFGYT-LAGNECVDTDECSVGNPCGNGTCKNV 2184
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGR 157
G F+C CE G+ P C D++EC + + RC NT GS+ C+C G+ L D R
Sbjct: 2185 IGGFECTCEEGFEPGPMM-TCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRR 2243
Query: 158 TCLGL-KLGWGV-SCQACPAQGSEL---YAVLCPEGPSK---DNGGADINECTAVPGACP 209
C + G C + L Y +C G + G D NEC PG C
Sbjct: 2244 MCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICE 2303
Query: 210 HGSCENLEPGYRCICDPGY--HPDADGLCRDIDE--C--DMHQSYCA-GGQCRNTAGSFT 262
+G C N Y C C+ G+ P+ D C D E C ++ Q+ C G RN
Sbjct: 2304 NGRCLNTRGSYTCECNDGFTASPNQDE-CLDNREGYCFTEVLQNMCQIGSSNRNPVTKSE 2362
Query: 263 CVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP--PTFPTRTELASPCDNGR 320
C C G P ++C +G + + RG + + C NG
Sbjct: 2363 CCCDGGRGWGPHCEIC----PFQGTVAFKKL-CPHGRGFMTNGADIDECKVIHDVCRNGE 2417
Query: 321 CINTHGGFECECELGYVLDATAQRCLD-NRRGSCWR------RVVDGQCEAAAPELLLRQ 373
C+N G + C C+ GY D T C+D N + + +G + + P+ + Q
Sbjct: 2418 CVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQ 2477
Query: 374 E----------CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA 423
E C GF + +C D +EC LC
Sbjct: 2478 EDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQ-HHTSCIDNNECTSDINLCG 2536
Query: 424 G-GTCVNTDGSYRCDCPPGLTLDSTGTA 450
G C NT GS+ C+C G +LD TG++
Sbjct: 2537 SKGICQNTPGSFTCECQRGFSLDQTGSS 2564
Score = 179 bits (435), Expect = 2e-44
Identities = 101/271 (37%), Positives = 132/271 (48%), Gaps = 13/271 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C N G + CICK GY G C D++EC P+ C C+NT GSY C C
Sbjct: 2412 VCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSC 2470
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DECA CVN+ G F C C G+ T +C+D +EC
Sbjct: 2471 PKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGF--TQHHTSCIDNNEC 2528
Query: 125 -EEQRVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSELY 181
+ +C G C NTPGSF CEC GF+L G +C + + CQ Y
Sbjct: 2529 TSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGY 2588
Query: 182 AVLCPEGPSKD---NGGADINECTAVPGACPHGSCENLEPGYRCICDPGY-HPDADGLCR 237
CP+G + N D NEC + C SC N Y+C+C G+ + G C+
Sbjct: 2589 RCSCPQGYLQHYQWNQCVDENECLSA-HICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ 2647
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
DI+EC Q+ C+ G C NT G + C CP G
Sbjct: 2648 DINECGSAQAPCSYG-CSNTEGGYLCGCPPG 2677
Score = 176 bits (428), Expect = 2e-43
Identities = 129/415 (31%), Positives = 180/415 (43%), Gaps = 64/415 (15%)
Query: 49 CRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEA 107
C+ +N+A Y LC G T+AG +D++ECA D +C G C N G+++C+C +
Sbjct: 696 CQPCPAQNSA-EYQALCSSGPGMTSAG--SDINECALDPDICPNGICENLRGTYKCICNS 752
Query: 108 GYRPTATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW 166
GY +T CVD++EC +C NG+C NTPGSF C C GF D +TC +
Sbjct: 753 GYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID--- 809
Query: 167 GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPG--YRCI 223
C++ P C G K++ G+ I EC++ P + C G ++ +
Sbjct: 810 --ECESSP----------CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTV 857
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDE 283
D + +G +C G C T +C +G Q C DIDE
Sbjct: 858 IDGRCEININGATLK-SQCCSSLGAAWGSPC--TLCQVDPICGKGYSRIKGTQ-CEDIDE 913
Query: 284 CEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQ 343
CE FP C NG C+NT G F+C+C G LDAT +
Sbjct: 914 CE-------------------VFP------GVCKNGLCVNTRGSFKCQCPSGMTLDATGR 948
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS--------XXXXXXXXXX 395
CLD R +C+ R D +C CCCSVG AWG+
Sbjct: 949 ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELC 1008
Query: 396 XXXKGFAKLDGAT----CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
GFA + +D++EC + LC G C NT GS++C C G LDS
Sbjct: 1009 PRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDS 1063
Score = 165 bits (400), Expect = 4e-40
Identities = 130/450 (28%), Positives = 175/450 (38%), Gaps = 73/450 (16%)
Query: 6 MCTNGICKNIDGGFECICKPGYE-SGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTC 63
+C +G C N DG + C C GY +G+E C D DEC NP C G C+N G + C
Sbjct: 2136 VCKHGQCINTDGSYRCECPFGYTLAGNE---CVDTDECSVGNP--CGNGTCKNVIGGFEC 2190
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
CE GF P C D++ECA + + RCVN+ GS++C C GY R C D DE
Sbjct: 2191 TCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDE 2250
Query: 124 CEE-QRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
CEE + C + C N G++ C C PG+ DG C+ CQ P
Sbjct: 2251 CEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDEN-----ECQTKPG----- 2300
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDI 239
+C G + G+ EC A P+ C + GY C + +C+
Sbjct: 2301 ---ICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGY-CFTEV-----LQNMCQ-- 2349
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYER 299
G RN C C G P ++C +G + + R
Sbjct: 2350 ----------IGSSNRNPVTKSECCCDGGRGWGPHCEIC----PFQGTVAFKKL-CPHGR 2394
Query: 300 GDIP--PTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRV 357
G + + C NG C+N G + C C+ GY D T C+D C
Sbjct: 2395 GFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVD--LNEC--NQ 2450
Query: 358 VDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECAL 417
C +C C G + DG +C+D+DECA
Sbjct: 2451 APKPCNFICKNTEGSYQCSCPKGY-------------------ILQEDGRSCKDLDECAT 2491
Query: 418 SAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
C CVNT G + C CPPG T T
Sbjct: 2492 KQHNCQ-FLCVNTIGGFTCKCPPGFTQHHT 2520
Score = 165 bits (400), Expect = 4e-40
Identities = 92/239 (38%), Positives = 118/239 (49%), Gaps = 19/239 (7%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
N ICKN +G ++C C GY +G C+D+DEC C+ C NT G +TC C PG
Sbjct: 2456 NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF-LCVNTIGGFTCKCPPG 2514
Query: 69 FAPTAAGYCADVDECAAD-SMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
F C D +EC +D ++C G C N+ GSF C C+ G+ T +C DVDECE
Sbjct: 2515 FTQHHTS-CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEG 2573
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSN------DGRTCLGLKLGWGVSCQACPAQGSEL 180
C++G C N G +RC C G+ D CL + G SC GS
Sbjct: 2574 NHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHN--TLGS-- 2628
Query: 181 YAVLCPEGPSKD--NGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
Y +CP G + +GG DINEC + C +G C N E GY C C PGY G C
Sbjct: 2629 YKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGYFRIGQGHC 2686
Score = 163 bits (397), Expect = 9e-40
Identities = 134/455 (29%), Positives = 182/455 (40%), Gaps = 65/455 (14%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVD 81
C+ G+ C+DVDEC+ P +C+ G C NT GS+ C C G C D+D
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 290
Query: 82 ECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN-TP 139
EC+ +C+GG C N+ S+ C C G+ + C+DV NGRC N P
Sbjct: 291 ECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLP 350
Query: 140 GSF-RCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC---------PEGP 189
S + +C D C G V+ + CP + +E + LC PE P
Sbjct: 351 QSITKMQC------CCDAGRC--WSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYP 402
Query: 190 SKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC 249
G I VP P G + P P D C + + C
Sbjct: 403 PPPLG--PIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLC 460
Query: 250 AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET----ETHYIESDYE---RGDI 302
G+C T GS+ C C +G + + + C D+DECE E + Y R
Sbjct: 461 QNGRCIPTPGSYRCECNKGFQLDLRGE-CIDVDECEKNPCAGGECINNQGSYTCQCRAGY 519
Query: 303 PPTFPTRTEL---------ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSC 353
T TRTE C+NGRCINT G F C C G+ + + C D S
Sbjct: 520 QSTL-TRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI 578
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVD 413
++G C +C C G S DG C+D++
Sbjct: 579 RNMCLNGMCINEDGSF----KCICKPGFQLAS-------------------DGRYCKDIN 615
Query: 414 ECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
EC + +C G CVNTDGSYRC+C PGL + G
Sbjct: 616 ECE-TPGICMNGRCVNTDGSYRCECFPGLAVGLDG 649
Score = 160 bits (388), Expect = 1e-38
Identities = 71/156 (45%), Positives = 89/156 (57%), Gaps = 5/156 (3%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C G + C C G++ G C DVDEC NP C G C N GSYTC C
Sbjct: 459 LCQNGRCIPTPGSYRCECNKGFQLDLRGE-CIDVDECEKNP--CAGGECINNQGSYTCQC 515
Query: 66 EPGFAPT-AAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
G+ T C D+DEC + +C GRC+N++GSF CVC AG+ T C D+DE
Sbjct: 516 RAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDE 575
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
C + +C NG C N GSF+C C PGF L++DGR C
Sbjct: 576 CSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC 611
Score = 129 bits (312), Expect = 2e-29
Identities = 61/162 (37%), Positives = 84/162 (51%), Gaps = 5/162 (3%)
Query: 8 TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEP 67
+ GIC+N G F C C+ G+ G+ C DVDEC N R C+ G C+N G Y C C
Sbjct: 2537 SKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQ 2594
Query: 68 GFAPTAA-GYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-E 125
G+ C D +EC + +C G C N+ GS++C+C AG++ G C D++EC
Sbjct: 2595 GYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGS 2654
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWG 167
Q C G C NT G + C C PG+ G G+ +G G
Sbjct: 2655 AQAPCSYG-CSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRG 2695
Score = 124 bits (298), Expect = 9e-28
Identities = 132/473 (27%), Positives = 173/473 (36%), Gaps = 69/473 (14%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C G C N+ G F C C+ GYE G C DV+EC D P C G C NT GSY C C
Sbjct: 1455 ICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTTCISGNCVNTPGSYICDC 1513
Query: 66 EPGFA--PTAAGYCADV--DECAADSMCKGGR----CVNSEG----SFQCVCEAGYRPTA 113
P F PT G C D C D +G C N G C C G
Sbjct: 1514 PPDFELNPTRVG-CVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGT 1572
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK-LGWGVSCQA 172
C V+ E + +C G FR P + D C L L G C
Sbjct: 1573 PCEMCPAVNTSEYKILCPGGE------GFRPN--PITVILEDIDECQELPGLCQGGKC-- 1622
Query: 173 CPAQGSELYAVLCPEGP--SKDNGGAD-INECTAVPGACPHGSCENLEPGYRCICDPGY- 228
GS + CP G ++D D +NEC PG C G+C N Y CIC P Y
Sbjct: 1623 INTFGS--FQCRCPTGYYLNEDTRVCDDVNECET-PGICGPGTCYNTVGNYTCICPPDYM 1679
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFT-----CVCPE--GTRHEPELQLCR-- 279
+ C D+ +++Y A Q + F C C G + C
Sbjct: 1680 QVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIP 1739
Query: 280 DIDECE---GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGY 336
DE G ++ Y +P E+ C+NG CIN G F CEC +G+
Sbjct: 1740 STDEFATLCGSQRPGFVIDIYT--GLPVDIDECREIPGVCENGVCINMVGSFRCECPVGF 1797
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
+ C D +D +C+ P EC + G
Sbjct: 1798 FYNDKLLVCED----------ID-ECQNG-PVCQRNAECINTAG-----------SYRCD 1834
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
G+ C D +EC +C+ G C++T GS+ C C G + T
Sbjct: 1835 CKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQT 1887
Score = 119 bits (287), Expect = 2e-26
Identities = 107/372 (28%), Positives = 141/372 (37%), Gaps = 64/372 (17%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT 72
N+ G + C PG+++ G C V CR + C G C C C G
Sbjct: 57 NVCGSRYNAYCCPGWKTLPGGNQCI-VPICRHS---CGDGFCSRPN---MCTCPSGQIAP 109
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
+ G + C M GG C + C+C+ GY T G V CE C N
Sbjct: 110 SCG-SRSIQHCNIRCM-NGGSCSDDH----CLCQKGYIGTHC-GQPV----CESG--CLN 156
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKD 192
G P RC C GFT R +S Q C Q L ++C +
Sbjct: 157 GGRCVAPN--RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQ---LSGIVCTK----- 206
Query: 193 NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA-DGLCRDIDECDMHQSYCAG 251
C A G CE + P C G+ P+ G C+D+DEC C G
Sbjct: 207 ------QLCCATVGRAWGHPCE-MCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQG 259
Query: 252 GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
G C NT GSF C CP G + Q C DIDEC T P
Sbjct: 260 GNCINTVGSFECKCPAGHKLNEVSQKCEDIDECS-------------------TIP---- 296
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLL 371
C+ G C NT + C+C G+ RC+D R G C+ + +G+C P+ +
Sbjct: 297 --GICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSIT 354
Query: 372 RQECCCSVGLAW 383
+ +CCC G W
Sbjct: 355 KMQCCCDAGRCW 366
Score = 111 bits (267), Expect = 5e-24
Identities = 92/330 (27%), Positives = 127/330 (38%), Gaps = 47/330 (14%)
Query: 1 MTNGGMCTNGICKNIDG-GF-----ECICKPGYESGSEGALCRDVDECRDNPRVCRRGRC 54
+ G C IC++ G GF C C G + S G+ R + C N R G C
Sbjct: 74 LPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGS--RSIQHC--NIRCMNGGSC 129
Query: 55 RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTA 113
+ CLC+ G+ T G + +S C GGRCV +C C G+
Sbjct: 130 SDDH----CLCQKGYIGTHCG------QPVCESGCLNGGRCVAPN---RCACTYGFTGP- 175
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQAC 173
+CE R R G C + C+ + C + WG C+ C
Sbjct: 176 ---------QCE--RDYRTGPCFTVISNQMCQGQLSGIVCTKQLCCATVGRAWGHPCEMC 224
Query: 174 PAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH-PDA 232
PAQ P + D++EC A+PG C G+C N + C C G+ +
Sbjct: 225 PAQPHPCRRGFIPN--IRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEV 282
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C DIDEC C GG+C NT S+ C CP G P+ C D+ Y
Sbjct: 283 SQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV-------RPGY 335
Query: 293 IESDYERGDIPPTFP-TRTELASPCDNGRC 321
+ G P + T++ CD GRC
Sbjct: 336 CYTALTNGRCSNQLPQSITKMQCCCDAGRC 365
Score = 78.2 bits (184), Expect = 6e-14
Identities = 46/136 (33%), Positives = 64/136 (47%), Gaps = 11/136 (8%)
Query: 314 SPCDNG-RCINTHGGFECECELGYVLDATAQRC-LDNRRGSCWRRVVDGQCEAAAPELLL 371
S C NG RC+ + C C G+ T +C D R G C+ + + C+ ++
Sbjct: 152 SGCLNGGRCVAPN---RCACTYGF----TGPQCERDYRTGPCFTVISNQMCQGQLSGIVC 204
Query: 372 -RQECCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVN 429
+Q CC +VG AWG +GF + C+DVDEC LC GG C+N
Sbjct: 205 TKQLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCIN 264
Query: 430 TDGSYRCDCPPGLTLD 445
T GS+ C CP G L+
Sbjct: 265 TVGSFECKCPAGHKLN 280
Score = 53.2 bits (122), Expect = 2e-06
Identities = 20/41 (48%), Positives = 23/41 (56%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
C D+DEC+ +C GG C NT SY C CPPG GT
Sbjct: 286 CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGT 326
Score = 32.3 bits (70), Expect = 3.6
Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNP 46
C+ G C N +GG+ C C PGY +G + R NP
Sbjct: 2659 CSYG-CSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNP 2697
>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
Length = 2871
Score = 316 bits (775), Expect = 1e-85
Identities = 176/479 (36%), Positives = 236/479 (49%), Gaps = 67/479 (13%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G C N G + C C+ GY+S CRD+DEC N R+C GRC NT GS+ C+C
Sbjct: 499 CAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCN 558
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF T G C D+DEC+ +MC G C+N +GSF+C+C+ G++ + C D++ECE
Sbjct: 559 AGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE 618
Query: 126 EQRVCRNG---------RCHNTPG-------------SFRCECLPGF-----------TL 152
+C NG RC PG R C G+ +
Sbjct: 619 TPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAV 678
Query: 153 SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS 212
+ C + +G CQ CPAQ S Y LC GP + G+DINEC P CP+G
Sbjct: 679 TKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGI 738
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
CENL Y+CIC+ GY D+ G C DI+EC ++ C GQCRNT GSF C CP+G +
Sbjct: 739 CENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIY 798
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR--CINTHGGFE 329
+P+L+ C DIDECE + + + P +F S D + CI T G
Sbjct: 799 KPDLKTCEDIDECESSPCINGVCK-----NSPGSFICECSSESTLDPTKTICIETIKG-T 852
Query: 330 CECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXX 389
C V+D RC N G+ + QC C S+G AWGS
Sbjct: 853 C---WQTVIDG---RCEININGA----TLKSQC-------------CSSLGAAWGS-PCT 888
Query: 390 XXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
KG++++ G C D+DEC + +C G CVNT GS++C CP G+TLD+TG
Sbjct: 889 LCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATG 947
Score = 268 bits (658), Expect = 2e-71
Identities = 162/467 (34%), Positives = 219/467 (46%), Gaps = 55/467 (11%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG T C N +G +EC C+PG+ + C D+DEC DNP +C G+C N G Y
Sbjct: 1205 NGGCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYR 1262
Query: 63 CLCEPGF-APTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
CLC GF A C DV+EC + ++C G C N++GSF C C+ GY + C D
Sbjct: 1263 CLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTD 1322
Query: 121 VDECE--EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSCQACPA 175
++ECE ++ C NT GSF+C C PG+ DG C L G + Q
Sbjct: 1323 INECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADC 1380
Query: 176 QGSE-LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ + Y LC EG + D D++EC+ C +G C N GYRC CD G+ P AD
Sbjct: 1381 KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSAD 1440
Query: 234 G-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
G C DIDEC + + C G C N G F C C G + C D++EC
Sbjct: 1441 GKACEDIDECSL-PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-------- 1491
Query: 293 IESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGS 352
+ PT C +G C+NT G + C+C + L+ T C+D R G+
Sbjct: 1492 ---------LDPT---------TCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGN 1533
Query: 353 CW---RRVVDGQCEAAAPEL---LLRQECCCSVGLAWGSXXXXXXXXXXXXXK------- 399
C+ R D A + E+ + + CCCS+G AWG+ K
Sbjct: 1534 CYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGE 1593
Query: 400 GFAKLD-GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
GF D+DEC LC GG C+NT GS++C CP G L+
Sbjct: 1594 GFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLN 1640
Score = 257 bits (629), Expect = 7e-68
Identities = 164/472 (34%), Positives = 217/472 (45%), Gaps = 40/472 (8%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C NG+C N+ G F C C G+ + +C D+DEC++ P R C NTAGSY C
Sbjct: 1775 GVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCD 1834
Query: 65 CEPGFAPTAAGYCADVDEC-AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C+PG+ T+ G C D +EC ++C G+C+++ GSF C+C G++ + C+D++E
Sbjct: 1835 CKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINE 1894
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSC---QACPAQG 177
CE C NG C NT GSF C C GF LS++ C+ + G G C Q G
Sbjct: 1895 CERD-ACGNGTCRNTIGSFNCRCNHGFILSHN-NDCIDVDECASGNGNLCRNGQCINTVG 1952
Query: 178 SELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
S + C EG G DINEC P C G+C+NL+ YRCIC PGY +
Sbjct: 1953 S--FQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE- 2009
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI--DECEGETETHY 292
C DIDEC CA G C NT GSF C+CPEG + C+D+ C + E
Sbjct: 2010 KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGK 2069
Query: 293 IESDYERGDIPPTFPTRTE---LASPCDNGRC-INTHGGFECECELGYVL----DATA-- 342
S R + PC+ C F C G + D +A
Sbjct: 2070 CSSPKSRNHSKQECCCALKGEGWGDPCE--LCPTEPDEAFRQICPYGSGIIVGPDDSAVD 2127
Query: 343 -QRCLDN---RRGSCWRRVVDGQCEAAAPELLLRQECC----CSVGLAWGSXX--XXXXX 392
C + + G C +CE +L EC CSVG G+
Sbjct: 2128 MDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGG 2187
Query: 393 XXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+GF TC D++ECA + LCA CVNT GSY C CP G L
Sbjct: 2188 FECTCEEGFEPGPMMTCEDINECAQNPLLCA-FRCVNTYGSYECKCPVGYVL 2238
Score = 250 bits (613), Expect = 6e-66
Identities = 158/489 (32%), Positives = 217/489 (44%), Gaps = 51/489 (10%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+CT+G C+N G F+C C G+ SE C D+DECR +P +C RG+C NT G + C C
Sbjct: 1038 LCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKC 1097
Query: 66 EPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+ G+ C D+DEC D +C+GG C N+EGS++C C G++ + AC+D++
Sbjct: 1098 DEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDIN 1157
Query: 123 ECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQG 177
ECE +C NGRC N G ++C C PG+ + D C+ + + G ++G
Sbjct: 1158 ECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEG 1217
Query: 178 SELYAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD- 233
S Y C G DI+EC P C G C N+ YRC+C G+ D
Sbjct: 1218 S--YECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDM 1275
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE---GETET 290
C D++ECD++ + C G C NT GSF C C G + C DI+ECE
Sbjct: 1276 KTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGK 1335
Query: 291 HYI----ESDYERGDIPPTFPTRTELA--SPCDNGR--------CINTHGGFECECELGY 336
H + ++ P + C NG C NT G + C C+ GY
Sbjct: 1336 HAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY 1395
Query: 337 VLD----ATAQRCLDN----RRGSCWRRVVDGQCE--------AAAPELLLRQECCCSVG 380
D C +N G C +CE A EC
Sbjct: 1396 TGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNI 1455
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
+G+ G+ +LD G C DV+EC L C G CVNT GSY CDC
Sbjct: 1456 CVFGTCHNLPGLFRCECEIGY-ELDRSGGNCTDVNEC-LDPTTCISGNCVNTPGSYICDC 1513
Query: 439 PPGLTLDST 447
PP L+ T
Sbjct: 1514 PPDFELNPT 1522
Score = 246 bits (601), Expect = 2e-64
Identities = 147/437 (33%), Positives = 210/437 (48%), Gaps = 45/437 (10%)
Query: 24 KPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADVDE 82
+PG+ L D+DECR+ P VC G C N GS+ C C G F C D+DE
Sbjct: 1752 RPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDE 1811
Query: 83 CAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPG 140
C +C + C+N+ GS++C C+ GYR T+T G C D +EC+E +C +G+C +T G
Sbjct: 1812 CQNGPVCQRNAECINTAGSYRCDCKPGYRFTST-GQCNDRNECQEIPNICSHGQCIDTVG 1870
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYAVLCPEG--PSKDNGGAD 197
SF C C GF ++D CL + +C + + + C G S +N D
Sbjct: 1871 SFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCID 1930
Query: 198 INECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCR 255
++EC + G C +G C N ++C C+ GY DG C DI+EC + CA G C+
Sbjct: 1931 VDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQ 1990
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N GS+ C+CP G + + + C DIDEC E E
Sbjct: 1991 NLDGSYRCICPPG--YSLQNEKCEDIDECVEEPEI------------------------- 2023
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C NT G F+C C G+ L ++ +RC D R C+ + G+C + +QEC
Sbjct: 2024 CALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQEC 2083
Query: 376 CCSV-GLAWGSXXXXXXXXXXXXXK-----GFAKLDGA--TCRDVDECALSAELCAGGTC 427
CC++ G WG + G + G + D+DEC ++C G C
Sbjct: 2084 CCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK-EPDVCKHGQC 2142
Query: 428 VNTDGSYRCDCPPGLTL 444
+NTDGSYRC+CP G L
Sbjct: 2143 INTDGSYRCECPFGYIL 2159
Score = 225 bits (549), Expect = 3e-58
Identities = 144/455 (31%), Positives = 204/455 (44%), Gaps = 64/455 (14%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVC--RRGRCRNTAGSYTCLCEPGF 69
C N G +EC C GY + +C+D DEC + C ++ C+N G+Y C+C PG+
Sbjct: 2221 CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGY 2280
Query: 70 APTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE--CE 125
G C D +EC +C+ GRC+N+ GS+ C C G+ + + C+D E C
Sbjct: 2281 QRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCF 2340
Query: 126 E---QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
Q +C+ G + P + + EC + GR GWG C+ CP QG+ +
Sbjct: 2341 TEVLQNMCQIGSSNRNPVT-KSECC-----CDGGR-------GWGPHCEICPFQGTVAFK 2387
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDE 241
LCP G GADI+EC + C +G C N Y CIC GY PD G C D++E
Sbjct: 2388 KLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNE 2447
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET-HYIESDYERG 300
C+ C C+NT GS+ C CP+G + + + C+D+DEC + ++ + G
Sbjct: 2448 CNQAPKPC-NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGG 2506
Query: 301 ---DIPPTFPTR----------TELASPC-DNGRCINTHGGFECECELGYVLDATAQRCL 346
PP F T + C G C NT G F CEC+ G+ LD T C
Sbjct: 2507 FTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE 2566
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
D C + +C+ ++ C C G
Sbjct: 2567 D--VDEC---EGNHRCQHGCQNIIGGYRCSCPQGY-------------------LQHYQW 2602
Query: 407 ATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
C D +EC LSA +C G +C NT GSY+C CP G
Sbjct: 2603 NQCVDENEC-LSAHICGGASCHNTLGSYKCMCPAG 2636
Score = 221 bits (541), Expect = 3e-57
Identities = 150/481 (31%), Positives = 210/481 (43%), Gaps = 60/481 (12%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G C+N+DG + CIC PGY +E C D+DEC + P +C G C NT GS+ CLC
Sbjct: 1984 CAPGTCQNLDGSYRCICPPGYSLQNEK--CEDIDECVEEPEICALGTCSNTEGSFKCLCP 2041
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVN----SEGSFQCVCEAGYRPTATRGACVDV 121
GF+ +++G C D+ + +GG+C + + +C C A +G
Sbjct: 2042 EGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC-------ALKGEGWG- 2093
Query: 122 DECEEQRVCRNGRCHNTPG-SFR--CECLPGFTLSNDGRTCLGLKLGWGVSC---QACPA 175
D CE C P +FR C G + D + C Q
Sbjct: 2094 DPCE--------LCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINT 2145
Query: 176 QGSELYAVLCPEGPS-KDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
GS Y CP G N D +EC+ V C +G+C+N+ G+ C C+ G+ P
Sbjct: 2146 DGS--YRCECPFGYILAGNECVDTDECS-VGNPCGNGTCKNVIGGFECTCEEGFEPGPMM 2202
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
C DI+EC + CA +C NT GS+ C CP G + ++C+D DECE E + E
Sbjct: 2203 TCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDECE-EGKHDCTE 2260
Query: 295 SDYERGDI--------PPTFPTRTE----------LASP--CDNGRCINTHGGFECECEL 334
E ++ P + R + P C+NGRC+NT G + CEC
Sbjct: 2261 KQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECND 2320
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPEL--LLRQECCCSVGLAWGSXXXXXXX 392
G+ CLDNR G C+ V+ C+ + + + ECCC G WG
Sbjct: 2321 GFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPF 2380
Query: 393 XXXXXXKGFAKLDG---ATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
K D+DEC + ++C G CVN GSY C C G T D TGT
Sbjct: 2381 QGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGT 2440
Query: 450 A 450
+
Sbjct: 2441 S 2441
Score = 220 bits (538), Expect = 7e-57
Identities = 142/423 (33%), Positives = 195/423 (46%), Gaps = 65/423 (15%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDEC-AADSMCKGGRC 94
+D++EC+ P +C G+CRNT GS+ C C+ GFA + C D+DEC + +C G+C
Sbjct: 1027 KDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQC 1086
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ G F+C C+ GY C+D+DEC+ + +CR G CHNT GS+RCEC PG L
Sbjct: 1087 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 1146
Query: 153 SNDGRTCLGLKLGWGVSCQACP-AQGSEL---YAVLCPEG--PSKDN-GGADINECTAVP 205
S + C+ + +S CP + L Y C G + D DI+EC+ +
Sbjct: 1147 SPNISACIDIN-ECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMN 1205
Query: 206 GACPHGSCENLEPGYRCICDPGY--HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
G C C N E Y C C PG+ PD C DIDEC+ + + C GGQC N G + C
Sbjct: 1206 GGC-ETFCTNSEGSYECSCQPGFALMPDQRS-CTDIDECEDNPNICDGGQCTNIPGEYRC 1263
Query: 264 VCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
+C +G +++ C D++EC D+ P C +G C N
Sbjct: 1264 LCYDGFMASEDMKTCVDVNEC----------------DLNPNI---------CLSGTCEN 1298
Query: 324 THGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAW 383
T G F C C++GY C D C + A +C CS G W
Sbjct: 1299 TKGSFICHCDMGYSGKKGKTGCTD--INECEIGAHNCGKHAVCTNTAGSFKCSCSPG--W 1354
Query: 384 GSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGL 442
DG C D+DEC+ +C+ C NT GSYRC C G
Sbjct: 1355 IG-------------------DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY 1395
Query: 443 TLD 445
T D
Sbjct: 1396 TGD 1398
Score = 213 bits (521), Expect = 8e-55
Identities = 154/463 (33%), Positives = 207/463 (44%), Gaps = 65/463 (14%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCLC 65
C NG C+N G F C C G+ S C DVDEC N +CR G+C NT GS+ C C
Sbjct: 1900 CGNGTCRNTIGSFNCRCNHGFIL-SHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQC 1958
Query: 66 EPGFAPTAAGY-CADVDECAADSM-CKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
G+ G C D++EC + C G C N +GS++C+C GY + C D+DE
Sbjct: 1959 NEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGY--SLQNEKCEDIDE 2016
Query: 124 C-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
C EE +C G C NT GSF+C C GF+LS+ GR C L++ + C A +G +
Sbjct: 2017 CVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSY---CYA-KFEGGK--- 2069
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCE--NLEP--GYRCICD--PGYHPDADGLC 236
C S+++ + C A+ G CE EP +R IC G D
Sbjct: 2070 --CSSPKSRNHSKQEC--CCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSA 2125
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE------GETET 290
D+DEC C GQC NT GS+ C CP G + C D DEC T
Sbjct: 2126 VDMDECK-EPDVCKHGQCINTDGSYRCECPFG--YILAGNECVDTDECSVGNPCGNGTCK 2182
Query: 291 HYI---ESDYERGDIPPTFPTRTELASPCDNG-----RCINTHGGFECECELGYVLDATA 342
+ I E E G P T ++ N RC+NT+G +EC+C +GYVL
Sbjct: 2183 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDR 2242
Query: 343 QRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
+ C D + +CE + +Q EC +G G+
Sbjct: 2243 RMCKD-----------EDECEEGKHDCTEKQMECKNLIG-----------TYMCICGPGY 2280
Query: 402 AKL-DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+ DG C D +EC +C G C+NT GSY C+C G T
Sbjct: 2281 QRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFT 2323
Score = 208 bits (507), Expect = 4e-53
Identities = 143/454 (31%), Positives = 198/454 (43%), Gaps = 48/454 (10%)
Query: 6 MCT-NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
MC+ + CKN G + C+CK GY +G C D+DEC +N +C G+C N G Y C
Sbjct: 1373 MCSQHADCKNTMGSYRCLCKEGYTG--DGFTCTDLDECSENLNLCGNGQCLNAPGGYRCE 1430
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C+ GF P+A G C D+DEC+ ++C G C N G F+C CE GY + G C DV+E
Sbjct: 1431 CDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNE 1490
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG-WGVSCQACPAQGSELYA 182
C + C +G C NTPGS+ C+C P F L+ C+ + G + + G +
Sbjct: 1491 CLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACS 1550
Query: 183 VLCPEGPSKDNGGADINECTAVP-GACPHGSCENLEPGYRCICDPGYHPD-ADGLCRDID 240
G SK + + + P CP + E C G+ P+ + DID
Sbjct: 1551 NEIGVGVSKASCCCSLGKAWGTPCEMCP--AVNTSEYKILCPGGEGFRPNPITVILEDID 1608
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERG 300
EC C GG+C NT GSF C CP G + ++C D++EC ET I G
Sbjct: 1609 ECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC----ETPGICGP---G 1661
Query: 301 DIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDG 360
T T + P + +GG C +D C N D
Sbjct: 1662 TCYNTVGNYTCICPP----DYMQVNGGNNC-------MDMRRSLCYRN-------YYADN 1703
Query: 361 Q-CEAAAPELLLRQECCCS--VGLAWGS--------XXXXXXXXXXXXXKGFAKLDGATC 409
Q C+ + ++ CCCS +G AW GF +D T
Sbjct: 1704 QTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFV-IDIYTG 1762
Query: 410 RDV--DECALSAELCAGGTCVNTDGSYRCDCPPG 441
V DEC +C G C+N GS+RC+CP G
Sbjct: 1763 LPVDIDECREIPGVCENGVCINMVGSFRCECPVG 1796
Score = 202 bits (493), Expect = 2e-51
Identities = 105/288 (36%), Positives = 140/288 (48%), Gaps = 21/288 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NG +C NG C N G F+C C GYE +G C D++EC PR C G C+N GSY
Sbjct: 1938 NGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYR 1997
Query: 63 CLCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C+C PG++ C D+DEC + +C G C N+EGSF+C+C G+ +++ C D+
Sbjct: 1998 CICPPGYS-LQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDL 2056
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK-LGWGVSCQACPAQGSEL 180
R C+ +C P + C LK GWG C+ CP + E
Sbjct: 2057 ---------RMSYCYAKFEGGKCSS-PKSRNHSKQECCCALKGEGWGDPCELCPTEPDEA 2106
Query: 181 YAVLCPEGP----SKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ +CP G D+ D++EC P C HG C N + YRC C GY A C
Sbjct: 2107 FRQICPYGSGIIVGPDDSAVDMDECKE-PDVCKHGQCINTDGSYRCECPFGYIL-AGNEC 2164
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
D DEC + C G C+N G F C C EG P + C DI+EC
Sbjct: 2165 VDTDECSVGNP-CGNGTCKNVIGGFECTCEEGFEPGP-MMTCEDINEC 2210
Score = 201 bits (491), Expect = 4e-51
Identities = 140/427 (32%), Positives = 181/427 (42%), Gaps = 51/427 (11%)
Query: 40 DECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEG 99
D C+ +C+ GRC T GS C C GF G C DVDEC + C GG C+N++G
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNP-CAGGECINNQG 509
Query: 100 SFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
S+ C C AGY+ T TR C D+DEC + R+C NGRC NT GSF C C GF ++ DG+
Sbjct: 510 SYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 569
Query: 159 CLGLK----LGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHG 211
C + ++ GS + +C G + G DINEC PG C +G
Sbjct: 570 CEDMDECSIRNMCLNGMCINEDGS--FKCICKPGFQLASDGRYCKDINEC-ETPGICMNG 626
Query: 212 SCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-RNTAGSFT---CVCP 266
C N + YRC C PG DG +C D GQC + G+ T C C
Sbjct: 627 RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCA 686
Query: 267 EGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELA-SP--CDNGRCIN 323
E C + Y + E A P C NG C N
Sbjct: 687 -----STEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICEN 741
Query: 324 THGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPELLLRQECCCSVGLA 382
G ++C C GY +D+T + C+D + D GQC + C C G
Sbjct: 742 LRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFV----CTCPKGFI 797
Query: 383 WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGL 442
+ K D TC D+DEC S C G C N+ GS+ C+C
Sbjct: 798 Y-------------------KPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSSES 836
Query: 443 TLDSTGT 449
TLD T T
Sbjct: 837 TLDPTKT 843
Score = 192 bits (467), Expect = 3e-48
Identities = 146/487 (29%), Positives = 195/487 (40%), Gaps = 86/487 (17%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRD----------VD-ECRDNPR-VCRRGRC 54
C NG+CKN G F C C +C + +D C N + +C
Sbjct: 816 CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC 875
Query: 55 RNTAGSY------TC----LCEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQC 103
++ G+ C +C G++ C D+DEC +CK G CVN+ GSF+C
Sbjct: 876 CSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKC 935
Query: 104 VCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C +G AT C+D+ R C C LP C +
Sbjct: 936 QCPSGMTLDATGRICLDI---------RLETCFLRYEDEECT-LPIAGRHRMDACCCSVG 985
Query: 164 LGWGVS-CQACPAQGSELYAVLCPEGP---SKD--NGG---ADINECTAVPGACPHGSCE 214
WG C+ CP + + Y LCP GP +K+ NG DINEC +P C HG C
Sbjct: 986 AAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCR 1045
Query: 215 NLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE- 272
N ++C CD G+ D++ C DIDEC + C GQC NT G F C C EG
Sbjct: 1046 NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGF 1105
Query: 273 PELQLCRDIDECEGET------ETHYIESDYERGDIPPTFPTRTEL------------AS 314
++ C DIDEC+ + H E Y R + PP + A
Sbjct: 1106 MMMKNCMDIDECQRDPLLCRGGVCHNTEGSY-RCECPPGHQLSPNISACIDINECELSAH 1164
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NGRC+N G ++C C GY C+D S +++G CE E
Sbjct: 1165 LCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECS----IMNGGCETFCTNSEGSYE 1220
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSY 434
C C G A D +C D+DEC + +C GG C N G Y
Sbjct: 1221 CSCQPGFA-------------------LMPDQRSCTDIDECEDNPNICDGGQCTNIPGEY 1261
Query: 435 RCDCPPG 441
RC C G
Sbjct: 1262 RCLCYDG 1268
Score = 190 bits (463), Expect = 9e-48
Identities = 131/450 (29%), Positives = 189/450 (42%), Gaps = 64/450 (14%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
G+ + D+DEC++ P +C+ G+C NT GS+ C C G+ C DV+EC
Sbjct: 1594 GFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECE 1653
Query: 85 ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC-RNGRCHNTPGSFR 143
+C G C N+ G++ C+C Y C+D+ + +C RN N
Sbjct: 1654 TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM----RRSLCYRNYYADNQT---- 1705
Query: 144 CECLPGFTLSNDGRTCLGLKLG--WGVSCQACPAQGSELYAVLC-PEGPS-----KDNGG 195
C+ F ++ C +G W C+ CP ++ +A LC + P
Sbjct: 1706 CDGELLFNMTKK-MCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP 1764
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPG-YHPDADGLCRDIDECDMHQSYCAGGQC 254
DI+EC +PG C +G C N+ +RC C G ++ D +C DIDEC +C
Sbjct: 1765 VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC 1824
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NTAGS+ C C G R Q C D +EC+ E+ +
Sbjct: 1825 INTAGSYRCDCKPGYRFTSTGQ-CNDRNECQ-------------------------EIPN 1858
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNR--------RGSCWRRVVDGQCEAAA 366
C +G+CI+T G F C C G+ + CLD G+C + C
Sbjct: 1859 ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNH 1918
Query: 367 PELLLRQECC-----CSVG----LAWGSXXXXXXXXXXXXXKGF-AKLDGATCRDVDECA 416
+L C C+ G G +G+ DG TC D++EC
Sbjct: 1919 GFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECL 1978
Query: 417 LSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
L CA GTC N DGSYRC CPPG +L +
Sbjct: 1979 LEPRKCAPGTCQNLDGSYRCICPPGYSLQN 2008
Score = 186 bits (453), Expect = 1e-46
Identities = 95/271 (35%), Positives = 129/271 (47%), Gaps = 13/271 (4%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C NG C N GG+ C C G+ ++G C D+DEC P +C G C N G +
Sbjct: 1411 NLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDEC-SLPNICVFGTCHNLPGLFR 1469
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C CE G+ + G C DV+EC + C G CVN+ GS+ C C + TR CVD
Sbjct: 1470 CECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDT 1529
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
+ R G C G +S C L WG C+ CPA + Y
Sbjct: 1530 ---RSGNCYLDIRPRGDNGDTACSNEIGVGVSK-ASCCCSLGKAWGTPCEMCPAVNTSEY 1585
Query: 182 AVLCPEGPS-KDNGGA----DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-L 235
+LCP G + N DI+EC +PG C G C N ++C C GY+ + D +
Sbjct: 1586 KILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRV 1645
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCP 266
C D++EC+ C G C NT G++TC+CP
Sbjct: 1646 CDDVNECET-PGICGPGTCYNTVGNYTCICP 1675
Score = 180 bits (438), Expect = 9e-45
Identities = 132/448 (29%), Positives = 186/448 (41%), Gaps = 45/448 (10%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNS 97
D+DEC++ P VC+ G+C NT GSY C C G+ A C D DEC+ + C G C N
Sbjct: 2127 DMDECKE-PDVCKHGQCINTDGSYRCECPFGYI-LAGNECVDTDECSVGNPCGNGTCKNV 2184
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGR 157
G F+C CE G+ P C D++EC + + RC NT GS+ C+C G+ L D R
Sbjct: 2185 IGGFECTCEEGFEPGPMM-TCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRR 2243
Query: 158 TCLGL-KLGWGV-SCQACPAQGSEL---YAVLCPEGPSK---DNGGADINECTAVPGACP 209
C + G C + L Y +C G + G D NEC PG C
Sbjct: 2244 MCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICE 2303
Query: 210 HGSCENLEPGYRCICDPGY--HPDADGLCRDIDE--C--DMHQSYCA-GGQCRNTAGSFT 262
+G C N Y C C+ G+ P+ D C D E C ++ Q+ C G RN
Sbjct: 2304 NGRCLNTRGSYTCECNDGFTASPNQDE-CLDNREGYCFTEVLQNMCQIGSSNRNPVTKSE 2362
Query: 263 CVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP--PTFPTRTELASPCDNGR 320
C C G P ++C +G + + RG + + C NG
Sbjct: 2363 CCCDGGRGWGPHCEIC----PFQGTVAFKKL-CPHGRGFMTNGADIDECKVIHDVCRNGE 2417
Query: 321 CINTHGGFECECELGYVLDATAQRCLD-NRRGSCWR------RVVDGQCEAAAPELLLRQ 373
C+N G + C C+ GY D T C+D N + + +G + + P+ + Q
Sbjct: 2418 CVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQ 2477
Query: 374 E----------CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA 423
E C GF + +C D +EC LC
Sbjct: 2478 EDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQ-HHTSCIDNNECTSDINLCG 2536
Query: 424 G-GTCVNTDGSYRCDCPPGLTLDSTGTA 450
G C NT GS+ C+C G +LD TG++
Sbjct: 2537 SKGICQNTPGSFTCECQRGFSLDQTGSS 2564
Score = 176 bits (428), Expect = 2e-43
Identities = 129/415 (31%), Positives = 180/415 (43%), Gaps = 64/415 (15%)
Query: 49 CRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEA 107
C+ +N+A Y LC G T+AG +D++ECA D +C G C N G+++C+C +
Sbjct: 696 CQPCPAQNSA-EYQALCSSGPGMTSAG--SDINECALDPDICPNGICENLRGTYKCICNS 752
Query: 108 GYRPTATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW 166
GY +T CVD++EC +C NG+C NTPGSF C C GF D +TC +
Sbjct: 753 GYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID--- 809
Query: 167 GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPG--YRCI 223
C++ P C G K++ G+ I EC++ P + C G ++ +
Sbjct: 810 --ECESSP----------CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTV 857
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDE 283
D + +G +C G C T +C +G Q C DIDE
Sbjct: 858 IDGRCEININGATLK-SQCCSSLGAAWGSPC--TLCQVDPICGKGYSRIKGTQ-CEDIDE 913
Query: 284 CEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQ 343
CE FP C NG C+NT G F+C+C G LDAT +
Sbjct: 914 CE-------------------VFP------GVCKNGLCVNTRGSFKCQCPSGMTLDATGR 948
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS--------XXXXXXXXXX 395
CLD R +C+ R D +C CCCSVG AWG+
Sbjct: 949 ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELC 1008
Query: 396 XXXKGFAKLDGAT----CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
GFA + +D++EC + LC G C NT GS++C C G LDS
Sbjct: 1009 PRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDS 1063
Score = 175 bits (426), Expect = 3e-43
Identities = 100/271 (36%), Positives = 131/271 (48%), Gaps = 13/271 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C N G + CICK GY G C D++EC P+ C C+NT GSY C C
Sbjct: 2412 VCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSC 2470
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DECA CVN+ G F C C G+ T +C+D +EC
Sbjct: 2471 PKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGF--TQHHTSCIDNNEC 2528
Query: 125 -EEQRVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSELY 181
+ +C G C NTPGSF CEC GF+L G +C + + CQ Y
Sbjct: 2529 TSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGY 2588
Query: 182 AVLCPEGPSKD---NGGADINECTAVPGACPHGSCENLEPGYRCICDPGY-HPDADGLCR 237
CP+G + N D NEC + C SC N Y+C+C G+ + G C+
Sbjct: 2589 RCSCPQGYLQHYQWNQCVDENECLSA-HICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ 2647
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
DI+EC Q+ C+ G NT G + C CP G
Sbjct: 2648 DINECGSAQAPCSYGS-SNTEGGYLCGCPPG 2677
Score = 169 bits (411), Expect = 2e-41
Identities = 107/294 (36%), Positives = 142/294 (48%), Gaps = 22/294 (7%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-C 77
F+ +C G + GA D+DEC+ VCR G C N GSY C+C+ G+ P G C
Sbjct: 2386 FKKLCPHGRGFMTNGA---DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC 2442
Query: 78 ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN 137
D++EC C N+EGS+QC C GY +C D+DEC ++ C N
Sbjct: 2443 VDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVN 2502
Query: 138 TPGSFRCECLPGFTLSN----DGRTCLG-LKL-GWGVSCQACPAQGSELYAVLCPEGPSK 191
T G F C+C PGFT + D C + L G CQ P GS + C G S
Sbjct: 2503 TIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTP--GS--FTCECQRGFSL 2558
Query: 192 DNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQS 247
D G+ D++EC C HG C+N+ GYRC C GY C D +EC +
Sbjct: 2559 DQTGSSCEDVDECEG-NHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENEC-LSAH 2615
Query: 248 YCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETETHYIESDYERG 300
C G C NT GS+ C+CP G ++E C+DI+EC + Y S+ E G
Sbjct: 2616 ICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGSSNTEGG 2669
Score = 164 bits (398), Expect = 7e-40
Identities = 130/450 (28%), Positives = 175/450 (38%), Gaps = 73/450 (16%)
Query: 6 MCTNGICKNIDGGFECICKPGYE-SGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTC 63
+C +G C N DG + C C GY +G+E C D DEC NP C G C+N G + C
Sbjct: 2136 VCKHGQCINTDGSYRCECPFGYILAGNE---CVDTDECSVGNP--CGNGTCKNVIGGFEC 2190
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
CE GF P C D++ECA + + RCVN+ GS++C C GY R C D DE
Sbjct: 2191 TCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDE 2250
Query: 124 CEE-QRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
CEE + C + C N G++ C C PG+ DG C+ CQ P
Sbjct: 2251 CEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDEN-----ECQTKPG----- 2300
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDI 239
+C G + G+ EC A P+ C + GY C + +C+
Sbjct: 2301 ---ICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGY-CFTEV-----LQNMCQ-- 2349
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYER 299
G RN C C G P ++C +G + + R
Sbjct: 2350 ----------IGSSNRNPVTKSECCCDGGRGWGPHCEIC----PFQGTVAFKKL-CPHGR 2394
Query: 300 GDIP--PTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRV 357
G + + C NG C+N G + C C+ GY D T C+D C
Sbjct: 2395 GFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVD--LNEC--NQ 2450
Query: 358 VDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECAL 417
C +C C G + DG +C+D+DECA
Sbjct: 2451 APKPCNFICKNTEGSYQCSCPKGY-------------------ILQEDGRSCKDLDECAT 2491
Query: 418 SAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
C CVNT G + C CPPG T T
Sbjct: 2492 KQHNCQ-FLCVNTIGGFTCKCPPGFTQHHT 2520
Score = 164 bits (398), Expect = 7e-40
Identities = 135/457 (29%), Positives = 188/457 (41%), Gaps = 71/457 (15%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF-A 70
CKN+ G + CIC PGY+ +G C D +EC+ P +C GRC NT GSYTC C GF A
Sbjct: 2265 CKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTA 2324
Query: 71 PTAAGYCADVDE--CAAD---SMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C D E C + +MC+ G N +C C+ G C
Sbjct: 2325 SPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTV 2384
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
+++C +GR T G+ EC + +G C+ +GS Y +
Sbjct: 2385 AFKKLCPHGRGFMTNGADIDECKVIHDVCRNGE-CVN-------------DRGS--YHCI 2428
Query: 185 CPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDID 240
C G + D G D+NEC P C + C+N E Y+C C GY DG C+D+D
Sbjct: 2429 CKTGYTPDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSCPKGYILQEDGRSCKDLD 2487
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEP----------ELQLCRDIDECEGETE 289
EC Q C C NT G FTC CP G T+H ++ LC C+
Sbjct: 2488 ECATKQHNCQF-LCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPG 2546
Query: 290 THYIESDYERGDIPPTFPTRTELASPCDNGR-----CINTHGGFECECELGYVLDATAQR 344
+ E +RG + E C+ C N GG+ C C GY+ +
Sbjct: 2547 SFTCEC--QRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQ 2604
Query: 345 CLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL 404
C+D C + G A+ L +C C G + +
Sbjct: 2605 CVD--ENECLSAHICG--GASCHNTLGSYKCMCPAGFQ------------------YEQF 2642
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C+D++EC + C+ G+ NT+G Y C CPPG
Sbjct: 2643 SGG-CQDINECGSAQAPCSYGSS-NTEGGYLCGCPPG 2677
Score = 163 bits (395), Expect = 2e-39
Identities = 92/239 (38%), Positives = 118/239 (49%), Gaps = 19/239 (7%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
N ICKN +G ++C C GY +G C+D+DEC C+ C NT G +TC C PG
Sbjct: 2456 NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF-LCVNTIGGFTCKCPPG 2514
Query: 69 FAPTAAGYCADVDECAAD-SMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
F C D +EC +D ++C G C N+ GSF C C+ G+ T +C DVDECE
Sbjct: 2515 FTQHHTS-CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEG 2573
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSN------DGRTCLGLKLGWGVSCQACPAQGSEL 180
C++G C N G +RC C G+ D CL + G SC GS
Sbjct: 2574 NHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHN--TLGS-- 2628
Query: 181 YAVLCPEGPSKD--NGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
Y +CP G + +GG DINEC + C +GS N E GY C C PGY G C
Sbjct: 2629 YKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGS-SNTEGGYLCGCPPGYFRIGQGHC 2686
Score = 161 bits (392), Expect = 3e-39
Identities = 134/455 (29%), Positives = 181/455 (39%), Gaps = 65/455 (14%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVD 81
C+ G+ C+DVDEC+ P +C+ G C NT GS+ C C G C D+D
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 290
Query: 82 ECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN-TP 139
EC+ +C+GG C N+ S+ C C G+ + C+DV NGRC N P
Sbjct: 291 ECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLP 350
Query: 140 GSF-RCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC---------PEGP 189
S + +C D C G V+ + CP + +E + LC PE P
Sbjct: 351 QSITKMQC------CCDAGRC--WSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYP 402
Query: 190 SKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC 249
G I VP P G + P P D C + + C
Sbjct: 403 PPPLG--PIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLC 460
Query: 250 AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET----ETHYIESDYE---RGDI 302
G+C T GS C C +G + + + C D+DECE E + Y R
Sbjct: 461 QNGRCIPTPGSCRCECNKGFQLDLRGE-CIDVDECEKNPCAGGECINNQGSYTCQCRAGY 519
Query: 303 PPTFPTRTEL---------ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSC 353
T TRTE C+NGRCINT G F C C G+ + + C D S
Sbjct: 520 QSTL-TRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI 578
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVD 413
++G C +C C G S DG C+D++
Sbjct: 579 RNMCLNGMCINEDGSF----KCICKPGFQLAS-------------------DGRYCKDIN 615
Query: 414 ECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
EC + +C G CVNTDGSYRC+C PGL + G
Sbjct: 616 ECE-TPGICMNGRCVNTDGSYRCECFPGLAVGLDG 649
Score = 158 bits (383), Expect = 4e-38
Identities = 71/156 (45%), Positives = 88/156 (56%), Gaps = 5/156 (3%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C G C C G++ G C DVDEC NP C G C N GSYTC C
Sbjct: 459 LCQNGRCIPTPGSCRCECNKGFQLDLRGE-CIDVDECEKNP--CAGGECINNQGSYTCQC 515
Query: 66 EPGFAPT-AAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
G+ T C D+DEC + +C GRC+N++GSF CVC AG+ T C D+DE
Sbjct: 516 RAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDE 575
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
C + +C NG C N GSF+C C PGF L++DGR C
Sbjct: 576 CSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC 611
Score = 157 bits (380), Expect = 1e-37
Identities = 117/386 (30%), Positives = 158/386 (40%), Gaps = 55/386 (14%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE--CRDN--PRVCRRGRC-RN 56
T G+C NG C N G + C C G+ + C D E C +C+ G RN
Sbjct: 2297 TKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRN 2356
Query: 57 TAGSYTCLCEPG--------------------FAPTAAGYC---ADVDEC-AADSMCKGG 92
C C+ G P G+ AD+DEC +C+ G
Sbjct: 2357 PVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNG 2416
Query: 93 RCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTL 152
CVN GS+ C+C+ GY P T +CVD++EC + N C NT GS++C C G+ L
Sbjct: 2417 ECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYIL 2476
Query: 153 SNDGRTCLGLK--LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGAC- 208
DGR+C L +CQ + CP G ++ + D NECT+ C
Sbjct: 2477 QEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCG 2536
Query: 209 PHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
G C+N + C C G+ D G C D+DEC+ + C G C+N G + C CP+
Sbjct: 2537 SKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQ 2594
Query: 268 GTRHEPELQLCRDIDECE-----GETETHYIESDYERGDIPPTFPTR---------TELA 313
G + C D +EC G H Y + P F E
Sbjct: 2595 GYLQHYQWNQCVDENECLSAHICGGASCHNTLGSY-KCMCPAGFQYEQFSGGCQDINECG 2653
Query: 314 S---PCDNGRCINTHGGFECECELGY 336
S PC G NT GG+ C C GY
Sbjct: 2654 SAQAPCSYGSS-NTEGGYLCGCPPGY 2678
Score = 125 bits (302), Expect = 3e-28
Identities = 60/162 (37%), Positives = 83/162 (51%), Gaps = 5/162 (3%)
Query: 8 TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEP 67
+ GIC+N G F C C+ G+ G+ C DVDEC N R C+ G C+N G Y C C
Sbjct: 2537 SKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHG-CQNIIGGYRCSCPQ 2594
Query: 68 GFAPTAA-GYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-E 125
G+ C D +EC + +C G C N+ GS++C+C AG++ G C D++EC
Sbjct: 2595 GYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGS 2654
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWG 167
Q C G NT G + C C PG+ G G+ +G G
Sbjct: 2655 AQAPCSYG-SSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRG 2695
Score = 124 bits (298), Expect = 9e-28
Identities = 132/473 (27%), Positives = 173/473 (36%), Gaps = 69/473 (14%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C G C N+ G F C C+ GYE G C DV+EC D P C G C NT GSY C C
Sbjct: 1455 ICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTTCISGNCVNTPGSYICDC 1513
Query: 66 EPGFA--PTAAGYCADV--DECAADSMCKGGR----CVNSEG----SFQCVCEAGYRPTA 113
P F PT G C D C D +G C N G C C G
Sbjct: 1514 PPDFELNPTRVG-CVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGT 1572
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK-LGWGVSCQA 172
C V+ E + +C G FR P + D C L L G C
Sbjct: 1573 PCEMCPAVNTSEYKILCPGGE------GFRPN--PITVILEDIDECQELPGLCQGGKC-- 1622
Query: 173 CPAQGSELYAVLCPEGP--SKDNGGAD-INECTAVPGACPHGSCENLEPGYRCICDPGY- 228
GS + CP G ++D D +NEC PG C G+C N Y CIC P Y
Sbjct: 1623 INTFGS--FQCRCPTGYYLNEDTRVCDDVNECET-PGICGPGTCYNTVGNYTCICPPDYM 1679
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFT-----CVCPE--GTRHEPELQLCR-- 279
+ C D+ +++Y A Q + F C C G + C
Sbjct: 1680 QVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIP 1739
Query: 280 DIDECE---GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGY 336
DE G ++ Y +P E+ C+NG CIN G F CEC +G+
Sbjct: 1740 STDEFATLCGSQRPGFVIDIYT--GLPVDIDECREIPGVCENGVCINMVGSFRCECPVGF 1797
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
+ C D +D +C+ P EC + G
Sbjct: 1798 FYNDKLLVCED----------ID-ECQNG-PVCQRNAECINTAG-----------SYRCD 1834
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
G+ C D +EC +C+ G C++T GS+ C C G + T
Sbjct: 1835 CKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQT 1887
Score = 119 bits (287), Expect = 2e-26
Identities = 107/372 (28%), Positives = 141/372 (37%), Gaps = 64/372 (17%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT 72
N+ G + C PG+++ G C V CR + C G C C C G
Sbjct: 57 NVCGSRYNAYCCPGWKTLPGGNQCI-VPICRHS---CGDGFCSRPN---MCTCPSGQIAP 109
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
+ G + C M GG C + C+C+ GY T G V CE C N
Sbjct: 110 SCG-SRSIQHCNIRCM-NGGSCSDDH----CLCQKGYIGTHC-GQPV----CESG--CLN 156
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKD 192
G P RC C GFT R +S Q C Q L ++C +
Sbjct: 157 GGRCVAPN--RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQ---LSGIVCTK----- 206
Query: 193 NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA-DGLCRDIDECDMHQSYCAG 251
C A G CE + P C G+ P+ G C+D+DEC C G
Sbjct: 207 ------TLCCATVGRAWGHPCE-MCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQG 259
Query: 252 GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
G C NT GSF C CP G + Q C DIDEC T P
Sbjct: 260 GNCINTVGSFECKCPAGHKLNEVSQKCEDIDECS-------------------TIP---- 296
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLL 371
C+ G C NT + C+C G+ RC+D R G C+ + +G+C P+ +
Sbjct: 297 --GICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSIT 354
Query: 372 RQECCCSVGLAW 383
+ +CCC G W
Sbjct: 355 KMQCCCDAGRCW 366
Score = 111 bits (267), Expect = 5e-24
Identities = 92/330 (27%), Positives = 127/330 (38%), Gaps = 47/330 (14%)
Query: 1 MTNGGMCTNGICKNIDG-GF-----ECICKPGYESGSEGALCRDVDECRDNPRVCRRGRC 54
+ G C IC++ G GF C C G + S G+ R + C N R G C
Sbjct: 74 LPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGS--RSIQHC--NIRCMNGGSC 129
Query: 55 RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTA 113
+ CLC+ G+ T G + +S C GGRCV +C C G+
Sbjct: 130 SDDH----CLCQKGYIGTHCG------QPVCESGCLNGGRCVAPN---RCACTYGFTGP- 175
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQAC 173
+CE R R G C + C+ + C + WG C+ C
Sbjct: 176 ---------QCE--RDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMC 224
Query: 174 PAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH-PDA 232
PAQ P + D++EC A+PG C G+C N + C C G+ +
Sbjct: 225 PAQPHPCRRGFIPN--IRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEV 282
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C DIDEC C GG+C NT S+ C CP G P+ C D+ Y
Sbjct: 283 SQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV-------RPGY 335
Query: 293 IESDYERGDIPPTFP-TRTELASPCDNGRC 321
+ G P + T++ CD GRC
Sbjct: 336 CYTALTNGRCSNQLPQSITKMQCCCDAGRC 365
Score = 76.2 bits (179), Expect = 2e-13
Identities = 45/136 (33%), Positives = 63/136 (46%), Gaps = 11/136 (8%)
Query: 314 SPCDNG-RCINTHGGFECECELGYVLDATAQRC-LDNRRGSCWRRVVDGQCEAAAPELLL 371
S C NG RC+ + C C G+ T +C D R G C+ + + C+ ++
Sbjct: 152 SGCLNGGRCVAPN---RCACTYGF----TGPQCERDYRTGPCFTVISNQMCQGQLSGIVC 204
Query: 372 RQE-CCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVN 429
+ CC +VG AWG +GF + C+DVDEC LC GG C+N
Sbjct: 205 TKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCIN 264
Query: 430 TDGSYRCDCPPGLTLD 445
T GS+ C CP G L+
Sbjct: 265 TVGSFECKCPAGHKLN 280
Score = 53.2 bits (122), Expect = 2e-06
Identities = 20/41 (48%), Positives = 23/41 (56%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
C D+DEC+ +C GG C NT SY C CPPG GT
Sbjct: 286 CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGT 326
>AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.
Length = 1365
Score = 316 bits (775), Expect = 1e-85
Identities = 176/479 (36%), Positives = 236/479 (49%), Gaps = 67/479 (13%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G C N G + C C+ GY+S CRD+DEC N R+C GRC NT GS+ C+C
Sbjct: 499 CAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCN 558
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF T G C D+DEC+ +MC G C+N +GSF+C+C+ G++ + C D++ECE
Sbjct: 559 AGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE 618
Query: 126 EQRVCRNG---------RCHNTPG-------------SFRCECLPGF-----------TL 152
+C NG RC PG R C G+ +
Sbjct: 619 TPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAV 678
Query: 153 SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS 212
+ C + +G CQ CPAQ S Y LC GP + G+DINEC P CP+G
Sbjct: 679 TKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGI 738
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
CENL Y+CIC+ GY D+ G C DI+EC ++ C GQCRNT GSF C CP+G +
Sbjct: 739 CENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIY 798
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR--CINTHGGFE 329
+P+L+ C DIDECE + + + P +F S D + CI T G
Sbjct: 799 KPDLKTCEDIDECESSPCINGVCK-----NSPGSFICECSSESTLDPTKTICIETIKG-T 852
Query: 330 CECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXX 389
C V+D RC N G+ + QC C S+G AWGS
Sbjct: 853 C---WQTVIDG---RCEININGA----TLKSQC-------------CSSLGAAWGS-PCT 888
Query: 390 XXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
KG++++ G C D+DEC + +C G CVNT GS++C CP G+TLD+TG
Sbjct: 889 LCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATG 947
Score = 223 bits (546), Expect = 8e-58
Identities = 108/292 (36%), Positives = 153/292 (52%), Gaps = 14/292 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+CT+G C+N G F+C C G+ SE C D+DECR +P +C RG+C NT G + C C
Sbjct: 1038 LCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKC 1097
Query: 66 EPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+ G+ C D+DEC D +C+GG C N+EGS++C C G++ + AC+D++
Sbjct: 1098 DEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDIN 1157
Query: 123 ECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQG 177
ECE +C NGRC N G ++C C PG+ + D C+ + + G ++G
Sbjct: 1158 ECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEG 1217
Query: 178 SELYAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD- 233
S Y C G DI+EC P C G C N+ YRC+C G+ D
Sbjct: 1218 S--YECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDM 1275
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C D++ECD++ + C G C NT GSF C C G + C DI+ECE
Sbjct: 1276 KTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECE 1327
Score = 203 bits (495), Expect = 1e-51
Identities = 113/313 (36%), Positives = 160/313 (51%), Gaps = 41/313 (13%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDEC-AADSMCKGGRC 94
+D++EC+ P +C G+CRNT GS+ C C+ GFA + C D+DEC + +C G+C
Sbjct: 1027 KDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQC 1086
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ G F+C C+ GY C+D+DEC+ + +CR G CHNT GS+RCEC PG L
Sbjct: 1087 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 1146
Query: 153 SNDGRTCLGLKLGWGVSCQACP-AQGSEL---YAVLCPEG--PSKDN-GGADINECTAVP 205
S + C+ + +S CP + L Y C G + D DI+EC+ +
Sbjct: 1147 SPNISACIDIN-ECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMN 1205
Query: 206 GACPHGSCENLEPGYRCICDPGY--HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
G C C N E Y C C PG+ PD C DIDEC+ + + C GGQC N G + C
Sbjct: 1206 GGC-ETFCTNSEGSYECSCQPGFALMPDQRS-CTDIDECEDNPNICDGGQCTNIPGEYRC 1263
Query: 264 VCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
+C +G +++ C D++EC D+ P C +G C N
Sbjct: 1264 LCYDGFMASEDMKTCVDVNEC----------------DLNPNI---------CLSGTCEN 1298
Query: 324 THGGFECECELGY 336
T G F C C++GY
Sbjct: 1299 TKGSFICHCDMGY 1311
Score = 201 bits (491), Expect = 4e-51
Identities = 140/427 (32%), Positives = 181/427 (42%), Gaps = 51/427 (11%)
Query: 40 DECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEG 99
D C+ +C+ GRC T GS C C GF G C DVDEC + C GG C+N++G
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNP-CAGGECINNQG 509
Query: 100 SFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
S+ C C AGY+ T TR C D+DEC + R+C NGRC NT GSF C C GF ++ DG+
Sbjct: 510 SYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 569
Query: 159 CLGLK----LGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHG 211
C + ++ GS + +C G + G DINEC PG C +G
Sbjct: 570 CEDMDECSIRNMCLNGMCINEDGS--FKCICKPGFQLASDGRYCKDINEC-ETPGICMNG 626
Query: 212 SCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-RNTAGSFT---CVCP 266
C N + YRC C PG DG +C D GQC + G+ T C C
Sbjct: 627 RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCA 686
Query: 267 EGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELA-SP--CDNGRCIN 323
E C + Y + E A P C NG C N
Sbjct: 687 -----STEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICEN 741
Query: 324 THGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPELLLRQECCCSVGLA 382
G ++C C GY +D+T + C+D + D GQC + C C G
Sbjct: 742 LRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFV----CTCPKGFI 797
Query: 383 WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGL 442
+ K D TC D+DEC S C G C N+ GS+ C+C
Sbjct: 798 Y-------------------KPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSSES 836
Query: 443 TLDSTGT 449
TLD T T
Sbjct: 837 TLDPTKT 843
Score = 192 bits (467), Expect = 3e-48
Identities = 146/487 (29%), Positives = 195/487 (40%), Gaps = 86/487 (17%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRD----------VD-ECRDNPR-VCRRGRC 54
C NG+CKN G F C C +C + +D C N + +C
Sbjct: 816 CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC 875
Query: 55 RNTAGSY------TC----LCEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQC 103
++ G+ C +C G++ C D+DEC +CK G CVN+ GSF+C
Sbjct: 876 CSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKC 935
Query: 104 VCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C +G AT C+D+ R C C LP C +
Sbjct: 936 QCPSGMTLDATGRICLDI---------RLETCFLRYEDEECT-LPIAGRHRMDACCCSVG 985
Query: 164 LGWGVS-CQACPAQGSELYAVLCPEGP---SKD--NGG---ADINECTAVPGACPHGSCE 214
WG C+ CP + + Y LCP GP +K+ NG DINEC +P C HG C
Sbjct: 986 AAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCR 1045
Query: 215 NLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE- 272
N ++C CD G+ D++ C DIDEC + C GQC NT G F C C EG
Sbjct: 1046 NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGF 1105
Query: 273 PELQLCRDIDECEGET------ETHYIESDYERGDIPPTFPTRTEL------------AS 314
++ C DIDEC+ + H E Y R + PP + A
Sbjct: 1106 MMMKNCMDIDECQRDPLLCRGGVCHNTEGSY-RCECPPGHQLSPNISACIDINECELSAH 1164
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NGRC+N G ++C C GY C+D S +++G CE E
Sbjct: 1165 LCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECS----IMNGGCETFCTNSEGSYE 1220
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSY 434
C C G A D +C D+DEC + +C GG C N G Y
Sbjct: 1221 CSCQPGFA-------------------LMPDQRSCTDIDECEDNPNICDGGQCTNIPGEY 1261
Query: 435 RCDCPPG 441
RC C G
Sbjct: 1262 RCLCYDG 1268
Score = 176 bits (428), Expect = 2e-43
Identities = 129/415 (31%), Positives = 180/415 (43%), Gaps = 64/415 (15%)
Query: 49 CRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEA 107
C+ +N+A Y LC G T+AG +D++ECA D +C G C N G+++C+C +
Sbjct: 696 CQPCPAQNSA-EYQALCSSGPGMTSAG--SDINECALDPDICPNGICENLRGTYKCICNS 752
Query: 108 GYRPTATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW 166
GY +T CVD++EC +C NG+C NTPGSF C C GF D +TC +
Sbjct: 753 GYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID--- 809
Query: 167 GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPG--YRCI 223
C++ P C G K++ G+ I EC++ P + C G ++ +
Sbjct: 810 --ECESSP----------CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTV 857
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDE 283
D + +G +C G C T +C +G Q C DIDE
Sbjct: 858 IDGRCEININGATLK-SQCCSSLGAAWGSPC--TLCQVDPICGKGYSRIKGTQ-CEDIDE 913
Query: 284 CEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQ 343
CE FP C NG C+NT G F+C+C G LDAT +
Sbjct: 914 CE-------------------VFP------GVCKNGLCVNTRGSFKCQCPSGMTLDATGR 948
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS--------XXXXXXXXXX 395
CLD R +C+ R D +C CCCSVG AWG+
Sbjct: 949 ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELC 1008
Query: 396 XXXKGFAKLDGAT----CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
GFA + +D++EC + LC G C NT GS++C C G LDS
Sbjct: 1009 PRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDS 1063
Score = 172 bits (419), Expect = 2e-42
Identities = 127/411 (30%), Positives = 174/411 (42%), Gaps = 68/411 (16%)
Query: 49 CRRGRCRNTAGSYTCLCE--PGFAP----TAAGYCADVDECAA-DSMCKGGRCVNSEGSF 101
C RNT Y LC PGFA + D++EC S+C G+C N+ GSF
Sbjct: 993 CEECPMRNTP-EYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSF 1051
Query: 102 QCVCEAGYRPTATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTC 159
+C C++G+ + C D+DEC +C G+C NTPG F C+C G+ + C
Sbjct: 1052 KCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNC 1111
Query: 160 LGLKLGWG--VSCQACPAQGSE-LYAVLCPEGPS-KDNGGA--DINECTAVPGACPHGSC 213
+ + + C+ +E Y CP G N A DINEC CP+G C
Sbjct: 1112 MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRC 1171
Query: 214 ENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE 272
NL Y+C C+PGYH D L C DIDEC + C C N+ GS+ C C G
Sbjct: 1172 VNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETF-CTNSEGSYECSCQPGFALM 1230
Query: 273 PELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECEC 332
P+ + C DIDECE D P + CD G+C N G + C C
Sbjct: 1231 PDQRSCTDIDECE---------------DNP----------NICDGGQCTNIPGEYRCLC 1265
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRV-VDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
G++ + C+D + + G CE + C C +G +
Sbjct: 1266 YDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFI----CHCDMGYS--------- 1312
Query: 392 XXXXXXXKGFAKLDGATCRDVDECALSAELCAG-GTCVNTDGSYRCDCPPG 441
K C D++EC + A C C NT GS++C C PG
Sbjct: 1313 ----------GKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPG 1353
Score = 161 bits (392), Expect = 3e-39
Identities = 134/455 (29%), Positives = 181/455 (39%), Gaps = 65/455 (14%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVD 81
C+ G+ C+DVDEC+ P +C+ G C NT GS+ C C G C D+D
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 290
Query: 82 ECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN-TP 139
EC+ +C+GG C N+ S+ C C G+ + C+DV NGRC N P
Sbjct: 291 ECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLP 350
Query: 140 GSF-RCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC---------PEGP 189
S + +C D C G V+ + CP + +E + LC PE P
Sbjct: 351 QSITKMQC------CCDAGRC--WSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYP 402
Query: 190 SKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC 249
G I VP P G + P P D C + + C
Sbjct: 403 PPPLG--PIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLC 460
Query: 250 AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET----ETHYIESDYE---RGDI 302
G+C T GS C C +G + + + C D+DECE E + Y R
Sbjct: 461 QNGRCIPTPGSCRCECNKGFQLDLRGE-CIDVDECEKNPCAGGECINNQGSYTCQCRAGY 519
Query: 303 PPTFPTRTEL---------ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSC 353
T TRTE C+NGRCINT G F C C G+ + + C D S
Sbjct: 520 QSTL-TRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI 578
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVD 413
++G C +C C G S DG C+D++
Sbjct: 579 RNMCLNGMCINEDGSF----KCICKPGFQLAS-------------------DGRYCKDIN 615
Query: 414 ECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
EC + +C G CVNTDGSYRC+C PGL + G
Sbjct: 616 ECE-TPGICMNGRCVNTDGSYRCECFPGLAVGLDG 649
Score = 158 bits (383), Expect = 4e-38
Identities = 71/156 (45%), Positives = 88/156 (56%), Gaps = 5/156 (3%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C G C C G++ G C DVDEC NP C G C N GSYTC C
Sbjct: 459 LCQNGRCIPTPGSCRCECNKGFQLDLRGE-CIDVDECEKNP--CAGGECINNQGSYTCQC 515
Query: 66 EPGFAPT-AAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
G+ T C D+DEC + +C GRC+N++GSF CVC AG+ T C D+DE
Sbjct: 516 RAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDE 575
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
C + +C NG C N GSF+C C PGF L++DGR C
Sbjct: 576 CSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC 611
Score = 141 bits (341), Expect = 5e-33
Identities = 67/164 (40%), Positives = 89/164 (54%), Gaps = 8/164 (4%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG T C N +G +EC C+PG+ + C D+DEC DNP +C G+C N G Y
Sbjct: 1205 NGGCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYR 1262
Query: 63 CLCEPGF-APTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
CLC GF A C DV+EC + ++C G C N++GSF C C+ GY + C D
Sbjct: 1263 CLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTD 1322
Query: 121 VDECE--EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL 162
++ECE ++ C NT GSF+C C PG+ DG C L
Sbjct: 1323 INECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDL 1364
Score = 119 bits (287), Expect = 2e-26
Identities = 107/372 (28%), Positives = 141/372 (37%), Gaps = 64/372 (17%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT 72
N+ G + C PG+++ G C V CR + C G C C C G
Sbjct: 57 NVCGSRYNAYCCPGWKTLPGGNQCI-VPICRHS---CGDGFCSRPN---MCTCPSGQIAP 109
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
+ G + C M GG C + C+C+ GY T G V CE C N
Sbjct: 110 SCG-SRSIQHCNIRCM-NGGSCSDDH----CLCQKGYIGTHC-GQPV----CESG--CLN 156
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKD 192
G P RC C GFT R +S Q C Q L ++C +
Sbjct: 157 GGRCVAPN--RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQ---LSGIVCTK----- 206
Query: 193 NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA-DGLCRDIDECDMHQSYCAG 251
C A G CE + P C G+ P+ G C+D+DEC C G
Sbjct: 207 ------TLCCATVGRAWGHPCE-MCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQG 259
Query: 252 GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
G C NT GSF C CP G + Q C DIDEC T P
Sbjct: 260 GNCINTVGSFECKCPAGHKLNEVSQKCEDIDECS-------------------TIP---- 296
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLL 371
C+ G C NT + C+C G+ RC+D R G C+ + +G+C P+ +
Sbjct: 297 --GICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSIT 354
Query: 372 RQECCCSVGLAW 383
+ +CCC G W
Sbjct: 355 KMQCCCDAGRCW 366
Score = 111 bits (267), Expect = 5e-24
Identities = 92/330 (27%), Positives = 127/330 (38%), Gaps = 47/330 (14%)
Query: 1 MTNGGMCTNGICKNIDG-GF-----ECICKPGYESGSEGALCRDVDECRDNPRVCRRGRC 54
+ G C IC++ G GF C C G + S G+ R + C N R G C
Sbjct: 74 LPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGS--RSIQHC--NIRCMNGGSC 129
Query: 55 RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTA 113
+ CLC+ G+ T G + +S C GGRCV +C C G+
Sbjct: 130 SDDH----CLCQKGYIGTHCG------QPVCESGCLNGGRCVAPN---RCACTYGFTGP- 175
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQAC 173
+CE R R G C + C+ + C + WG C+ C
Sbjct: 176 ---------QCE--RDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMC 224
Query: 174 PAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH-PDA 232
PAQ P + D++EC A+PG C G+C N + C C G+ +
Sbjct: 225 PAQPHPCRRGFIPN--IRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEV 282
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C DIDEC C GG+C NT S+ C CP G P+ C D+ Y
Sbjct: 283 SQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV-------RPGY 335
Query: 293 IESDYERGDIPPTFP-TRTELASPCDNGRC 321
+ G P + T++ CD GRC
Sbjct: 336 CYTALTNGRCSNQLPQSITKMQCCCDAGRC 365
Score = 96.7 bits (230), Expect = 1e-19
Identities = 44/123 (35%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C NI G + C+C G+ + + C DV+EC NP +C G C NT GS+
Sbjct: 1245 NPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFI 1304
Query: 63 CLCEPGFA-PTAAGYCADVDEC--AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C+ G++ C D++EC A + K C N+ GSF+C C G+ + C
Sbjct: 1305 CHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIK--CT 1362
Query: 120 DVD 122
D+D
Sbjct: 1363 DLD 1365
Score = 76.2 bits (179), Expect = 2e-13
Identities = 45/136 (33%), Positives = 63/136 (46%), Gaps = 11/136 (8%)
Query: 314 SPCDNG-RCINTHGGFECECELGYVLDATAQRC-LDNRRGSCWRRVVDGQCEAAAPELLL 371
S C NG RC+ + C C G+ T +C D R G C+ + + C+ ++
Sbjct: 152 SGCLNGGRCVAPN---RCACTYGF----TGPQCERDYRTGPCFTVISNQMCQGQLSGIVC 204
Query: 372 RQE-CCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVN 429
+ CC +VG AWG +GF + C+DVDEC LC GG C+N
Sbjct: 205 TKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCIN 264
Query: 430 TDGSYRCDCPPGLTLD 445
T GS+ C CP G L+
Sbjct: 265 TVGSFECKCPAGHKLN 280
Score = 53.2 bits (122), Expect = 2e-06
Identities = 20/41 (48%), Positives = 23/41 (56%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
C D+DEC+ +C GG C NT SY C CPPG GT
Sbjct: 286 CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGT 326
>AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 3 protein.
Length = 2809
Score = 308 bits (756), Expect = 3e-83
Identities = 170/465 (36%), Positives = 236/465 (50%), Gaps = 39/465 (8%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C +G C NI G + C C PG+++ C DVDEC + +C GRC NT GS+ C+C
Sbjct: 458 CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + G C D +ECA +MC G C+N +GSF C+C+ G+ C+D+DEC+
Sbjct: 518 AGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ 577
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG---WGV----SCQACPAQGS 178
+C NG C NT GSFRC+CL G + DGR C+ + +G SC A P G+
Sbjct: 578 TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC-ARPFPGT 636
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
+ C P D+G + C P S E ++ +C G DG RD
Sbjct: 637 VTKSECCCANP--DHGFGE--PCQLCPA---KNSAE-----FQALCSSGLGITTDG--RD 682
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIES 295
I+EC + CA G C N GS+ CVC G + C D+DEC + + + ++
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQN 742
Query: 296 D--YERGDIPPTFP--TRTE--------LASPCDNGRCINTHGGFECECELGYVLDATAQ 343
PP F TE L+SPC +G C N G + C+C G LD +
Sbjct: 743 SPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGT 802
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
CLD+ +G+CW ++ + +CE LR ECC ++G AWGS +GFA+
Sbjct: 803 FCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS-PCERCEIDPACARGFAR 861
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+ G TC DV+EC +C G CVNT GS+RC+CP GL LD++G
Sbjct: 862 MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 263 bits (644), Expect = 1e-69
Identities = 165/493 (33%), Positives = 222/493 (45%), Gaps = 55/493 (11%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+CT+G C+N G F C C G+ ++ C D+DECR +P +C +G C NT GS+ C
Sbjct: 995 GLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 65 CEPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG+ C DVDECA D +C+GG C N++GS++C C G+ TA AC D+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDI 1114
Query: 122 DECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQ 176
DEC +C +G+C N G+F+C C GF + D + C+ + G +
Sbjct: 1115 DECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE 1174
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
GS Y C +G S G AD++EC P C G C N+ G+RC+C G+ D
Sbjct: 1175 GS--YRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C D+DECD++ C G C NT GSF C C G C D+DEC E H
Sbjct: 1233 MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC--EVGGHN 1290
Query: 293 IESDYERGDIPPTFPTR---------------TELASP---CD-NGRCINTHGGFECECE 333
+S +IP +F R E S C G C+N G + C C
Sbjct: 1291 CDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 334 LGYVLDA----TAQRCLDN----RRGSCWRRVVDGQCEAAA---PELLLR-----QECCC 377
G+ D C +N G C +CE P R EC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ 1410
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYR 435
A+GS G+ +LD G C D++ECA C G C+NT GSY
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGY-ELDRGGGNCTDINECADPVN-CINGVCINTPGSYL 1468
Query: 436 CDCPPGLTLDSTG 448
C CP L+ +G
Sbjct: 1469 CSCPQDFELNPSG 1481
Score = 251 bits (614), Expect = 4e-66
Identities = 154/458 (33%), Positives = 196/458 (42%), Gaps = 60/458 (13%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RG-RCRNTAGSYTCLCEPGF 69
C N +G + C C GY +GA+CRDVDEC D + C RG C+N G++ C+C PG
Sbjct: 2181 CHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGM 2240
Query: 70 APTAAGY--CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
P C D +EC A +C GRCVN+ GSF+C C+ G++P+ T C D+
Sbjct: 2241 RPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDI----- 2295
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
R G C C L + + C G GWG C+ CP G+ Y LC
Sbjct: 2296 ----RQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLC 2351
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
P G G D++EC + C HG C N +RC C GY PDA C D+DEC
Sbjct: 2352 PHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQ 2411
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI-- 302
C C+NT GSF C CP G E + + C+D+DEC G
Sbjct: 2412 VPKPCT-FLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTC 2470
Query: 303 --PPTFPTRTELA----------SPCD-NGRCINTHGGFECECELGYVLDATAQRCLDNR 349
PP F + PC +G C NT G F CEC G+ L ++ C D
Sbjct: 2471 RCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED-- 2528
Query: 350 RGSCWRRVVDG--QCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA 407
C DG +C+ L C C G S A
Sbjct: 2529 VNEC-----DGPHRCQHGCQNQLGGYRCSCPQGFTQHS-------------------QWA 2564
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
C D +ECALS C +C NT G +RC CP G D
Sbjct: 2565 QCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFD 2602
Score = 236 bits (578), Expect = 1e-61
Identities = 158/481 (32%), Positives = 217/481 (45%), Gaps = 47/481 (9%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G C G C+N++G F CIC PG++ S+ C D+DEC + P +C G C N+ GS+ CL
Sbjct: 1938 GTCLPGTCQNLEGSFRCICPPGFQVQSDH--CIDIDECSEEPNLCLFGTCTNSPGSFQCL 1995
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCV--NSEGSFQCVCEAGYRPTATRGACVDV 121
C PGF + G+ C D + + + G+C + + + C RP G
Sbjct: 1996 CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWG----- 2050
Query: 122 DECEEQRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D CE +C F +PG S + G + GS
Sbjct: 2051 DPCE---LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGS- 2106
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ CP G S D G D +EC+ V C G+C N+ G+ C C G+ P C
Sbjct: 2107 -FRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCTNVIGGFECACADGFEPGLMMTC 2164
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETETHY--I 293
DIDEC ++ CA +C NT GS+ C CP G + +CRD+DEC +G+ + H +
Sbjct: 2165 EDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM 2223
Query: 294 ESDYERGDI----PP---TFPTRTE--------LASP--CDNGRCINTHGGFECECELGY 336
E G PP P E A P C NGRC+NT G F C+C+ G+
Sbjct: 2224 ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGF 2283
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEA--AAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
T C D R+G C+ V+ C + ++ E + R ECCC G WG
Sbjct: 2284 QPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPG 2343
Query: 395 XXXXKGFAKL-DGATC--RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
+ G T RDVDEC + A LCA G C+N+ GS+RC C G T D+T T
Sbjct: 2344 TSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Query: 452 L 452
L
Sbjct: 2404 L 2404
Score = 235 bits (574), Expect = 3e-61
Identities = 148/442 (33%), Positives = 197/442 (44%), Gaps = 46/442 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDEC 83
PG+ + D+DEC + P +C G C N GS+ C C GF + C DVDEC
Sbjct: 1708 PGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC 1767
Query: 84 AA-DSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPG 140
+ +S C + C+N GS++C C GY+ + GACV +EC E VC +G C +T G
Sbjct: 1768 GSRESPCQQNADCINIPGSYRCKCTRGYK-LSPGGACVGRNECREIPNVCSHGDCMDTEG 1826
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG-SELYAVLCPEGPSKDNGG--AD 197
S+ C C GF S D C+ + C + Y LC G + G D
Sbjct: 1827 SYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVD 1886
Query: 198 INECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCR 255
+ECT + G C G C N + C+C G+ ADG C D +EC C G C+
Sbjct: 1887 FDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N GSF C+CP G + + C DIDEC E
Sbjct: 1947 NLEGSFRCICPPG--FQVQSDHCIDIDECSEEPNL------------------------- 1979
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C N+ G F+C C G+VL RC D R+ C+ R G+C + C
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 376 CCS--VGLAWGSXXXXXXXXXXXXXK-----GFAKLDGA--TCRDVDECALSAELCAGGT 426
CCS G WG + G + G + DV+ECA + +C G
Sbjct: 2040 CCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGV 2099
Query: 427 CVNTDGSYRCDCPPGLTLDSTG 448
CVNTDGS+RC+CP G +LD TG
Sbjct: 2100 CVNTDGSFRCECPFGYSLDFTG 2121
Score = 225 bits (550), Expect = 3e-58
Identities = 154/461 (33%), Positives = 202/461 (43%), Gaps = 58/461 (12%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG+C+N+ G + C+C GYE+G+ G C DVDEC N +C G C+N+ GSY+C C
Sbjct: 692 VCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSC 751
Query: 66 EPGF-APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
PGF C DVDEC + S C G C N GS+ C C G R + C+D
Sbjct: 752 PPGFHFWQDTEICKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD---- 806
Query: 125 EEQRVCRNGRCHNTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
G C RCE L G +L ++ C L WG C+ C +
Sbjct: 807 -----STKGTCWLKIQESRCEVNLQGASLRSE--CCATLGAAWGSPCERCEIDPA----- 854
Query: 184 LCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDI- 239
C G ++ G D+NEC + PG CP+G C N +RC C G DA G LC D+
Sbjct: 855 -CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVR 913
Query: 240 -DECDMH--QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET----ETHY 292
+ C + + C G C C G E + C D + E + +
Sbjct: 914 LEPCFLRWDEDEC-GVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGF 972
Query: 293 IESDYERGDIPPTFPTRTE---LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
D+ G P + E C +G C NT G F C C G+ LDA + C D
Sbjct: 973 ASRDFLSG--RPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD-- 1028
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
+D +C +P+L C G + GF + C
Sbjct: 1029 --------ID-ECR-ISPDL-------CGQGTCVNTPGSFECECFPGYESGFMLM--KNC 1069
Query: 410 RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
DVDECA LC GGTC NTDGSY+C CPPG L + GTA
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTA 1110
Score = 224 bits (547), Expect = 6e-58
Identities = 150/457 (32%), Positives = 195/457 (42%), Gaps = 72/457 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C N G F C+C+ G+E ++G C D +EC C G C+N GS+ C
Sbjct: 1895 GQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRC 1954
Query: 64 LCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PGF + +C D+DEC+ + ++C G C NS GSFQC+C G+ + C D
Sbjct: 1955 ICPPGF-QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDT- 2012
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSEL 180
R C + +C F + R C + GWG C+ CP +GS
Sbjct: 2013 --------RQSFCFTRFEAGKCSVPKAFNTTKT-RCCCSKRPGEGWGDPCELCPQEGSAA 2063
Query: 181 YAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
+ LCP G P D+ D+NEC PG C +G C N + +RC C GY D G+
Sbjct: 2064 FQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGIN 2123
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL-CRDIDECEGETETHYIE 294
C D DEC + C G C N G F C C +G EP L + C DIDEC
Sbjct: 2124 CVDTDECSVGHP-CGQGTCTNVIGGFECACADG--FEPGLMMTCEDIDEC---------- 2170
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCW 354
+ P A C N T G + C C GY L C D C
Sbjct: 2171 ------SLNPLL-----CAFRCHN-----TEGSYLCTCPAGYTLREDGAMCRD--VDEC- 2211
Query: 355 RRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA--TCRDV 412
DGQ + A + EC +G G L G+ C D
Sbjct: 2212 ---ADGQQDCHARGM----ECKNLIG-----------TFACVCPPGMRPLPGSGEGCTDD 2253
Query: 413 DECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+EC +LC G CVNT GS+RCDC G T T
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLT 2290
Score = 217 bits (529), Expect = 9e-56
Identities = 143/421 (33%), Positives = 184/421 (43%), Gaps = 61/421 (14%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDEC-AADSMCKGGRC 94
+DV+EC+ P +C G CRNT GS+ C C GFA A C D+DEC + +C G C
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ GSF+C C GY C+DVDEC + +CR G C NT GS++C+C PG L
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 153 SNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG-ADINECTAVPG 206
+ G C + L G+ + C G + D G DINEC G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 207 ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
C C N E YRC C GY DG C D+DEC+ + C G C N G C+C
Sbjct: 1165 GC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLC 1223
Query: 266 PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTH 325
+G P+++ C D+DEC D+ P C +G C NT
Sbjct: 1224 YDGFMATPDMRTCVDVDEC----------------DLNPHI---------CLHGDCENTK 1258
Query: 326 GGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
G F C C+LGY++ A C D C V C++ A L + C W
Sbjct: 1259 GSFVCHCQLGYMVRKGATGCSD--VDEC--EVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTL 444
DG C D+DEC C+ G C+N GSYRC C G
Sbjct: 1315 -------------------DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 445 D 445
D
Sbjct: 1356 D 1356
Score = 210 bits (513), Expect = 8e-54
Identities = 102/272 (37%), Positives = 143/272 (52%), Gaps = 12/272 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCL 64
+C NGIC N G F C C G+ S C DVDEC C++ C N GSY C
Sbjct: 1731 ICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 65 CEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G+ + G C +EC ++C G C+++EGS+ C+C G++ +A + C+D+DE
Sbjct: 1791 CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDE 1850
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP----AQGSE 179
C+ Q C NG C N GS+ C C PGF ++++G C+ + Q C +
Sbjct: 1851 CDRQ-PCGNGTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAG 1908
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ LC +G G D NEC ++ G C G+C+NLE +RCIC PG+ +D C
Sbjct: 1909 SFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDH-C 1967
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
DIDEC + C G C N+ GSF C+CP G
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPG 1999
Score = 206 bits (503), Expect = 1e-52
Identities = 161/471 (34%), Positives = 197/471 (41%), Gaps = 70/471 (14%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C G C N+ GGFEC C G+E G C D+DEC NP +C RC NT GSY C
Sbjct: 2133 GHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDIDECSLNPLLCAF-RCHNTEGSYLC 2190
Query: 64 LCEPGFAPTAAG-YCADVDECA---ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG-AC 118
C G+ G C DVDECA D +G C N G+F CVC G RP G C
Sbjct: 2191 TCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Query: 119 VDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
D +EC Q +C NGRC NT GSFRC+C GF S C ++ G C A
Sbjct: 2251 TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG---PCFA----- 2302
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLE-PG---YRCICDPGYHPDAD 233
E+ +C S + EC G CE PG YR +C G A+
Sbjct: 2303 -EVLQTMC-RSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE 2360
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G RD+DEC M CA G+C N+ GSF C C G + C D+DEC
Sbjct: 2361 G--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDEC--------- 2409
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD-----N 348
+++ PC C NT G F C C GY+L+ + C D +
Sbjct: 2410 ----------------SQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS 2452
Query: 349 RRGSCWRRVVD--GQCEAAAPELLLRQ--------ECCCSVGL--AWGSXXXXXXXXXXX 396
R+ +C V+ G P + EC G A G
Sbjct: 2453 RQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCE 2512
Query: 397 XXKGFAKLD-GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+GF + G C DV+EC C G C N G YRC CP G T S
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHS 2561
Score = 201 bits (490), Expect = 5e-51
Identities = 150/455 (32%), Positives = 193/455 (42%), Gaps = 42/455 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ GG C+C G+ + + C DVDEC NP +C G C NT GS+
Sbjct: 1203 NPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFV 1262
Query: 63 CLCEPGF-APTAAGYCADVDEC-AADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C+ G+ A C+DVDEC C C+N GSF C C G+ C
Sbjct: 1263 CHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECH 1320
Query: 120 DVDEC--EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC-----LGLKLGWGVSCQA 172
D+DEC +E R G C N PGS+RC C GF + DG C + + Q
Sbjct: 1321 DLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQC 1378
Query: 173 CPAQGSELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A G Y C G P++D+ D++EC A C GSCENL +RCIC+ GY
Sbjct: 1379 LNAPGG--YRCECEMGFDPTEDHRACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYE 1435
Query: 230 PD-ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET 288
D G C DI+EC C G C NT GS+ C CP+ P C D
Sbjct: 1436 LDRGGGNCTDINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFL 1494
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYVLDATAQRCL- 346
ETH +RGD E+ C + G + CEL + + T R L
Sbjct: 1495 ETH------DRGD--SGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLC 1546
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
G R+ ++ EC GL G L
Sbjct: 1547 PGGEGFQPNRIT-----VILEDI---DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 407 AT--CRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
T C D+DEC+ + +C GTC NT G+Y C CP
Sbjct: 1599 HTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 196 bits (477), Expect = 2e-49
Identities = 147/440 (33%), Positives = 184/440 (41%), Gaps = 47/440 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECA 84
PG + L + +D CR +C GRC T SY C C G+ G C DVDEC
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT 454
Query: 85 ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFR 143
+ S C G CVN G++ C C G++ T TR ACVDVDEC +C GRC NT GSF+
Sbjct: 455 S-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQ 513
Query: 144 CECLPGFTLSNDGRTCLG-LKLGWGVSC--QACPAQGSELYAVLCPEGPSKDNGG---AD 197
C C GF LS DG+ C+ + C C + ++ LC G GG D
Sbjct: 514 CVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGS-FSCLCKPGFLLAPGGHYCMD 572
Query: 198 INECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-R 255
I+EC PG C +G C N E +RC C G DG +C D G C R
Sbjct: 573 IDEC-QTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCAR 631
Query: 256 NTAGSFT---CVC--PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G+ T C C P+ EP QLC + E + G
Sbjct: 632 PFPGTVTKSECCCANPDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDP 690
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPEL 369
E+ C NG C N G + C C LGY A+ + C D + + D G C+ +
Sbjct: 691 EV---CANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGS- 746
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + D C+DVDEC S C G C N
Sbjct: 747 ---YSCSCPPGFHFWQ-------------------DTEICKDVDECLSSP--CVSGVCRN 782
Query: 430 TDGSYRCDCPPGLTLDSTGT 449
GSY C C PG LD +GT
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT 802
Score = 193 bits (471), Expect = 9e-49
Identities = 109/272 (40%), Positives = 138/272 (50%), Gaps = 14/272 (5%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G C N G F C C+ GY + C D+DEC P+ C C+NT GS+ C C
Sbjct: 2373 LCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSC 2431
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DEC + CVN+ G+F C C G+ T AC D DEC
Sbjct: 2432 PRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGF--TQHHQACFDNDEC 2489
Query: 125 EEQ-RVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQ-ACPAQGSEL 180
Q C +G CHNTPGSFRCEC GFTL + G C + G CQ C Q
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGG- 2548
Query: 181 YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLC 236
Y CP+G ++ + A D NEC P C SC N G+RC+C G+ D A G C
Sbjct: 2549 YRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGC 2608
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
+D+DEC + C+ C NT G F C CP+G
Sbjct: 2609 QDVDECAGRRGPCS-YSCANTPGGFLCGCPQG 2639
Score = 187 bits (456), Expect = 6e-47
Identities = 155/470 (32%), Positives = 194/470 (41%), Gaps = 88/470 (18%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C NG C+N G + C C PG+ + +C+DVDEC +P C G CRN AGSYT
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYT 788
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRC-VNSEGS---FQCVCEAG--------- 108
C C PG +G +C D + + RC VN +G+ +C G
Sbjct: 789 CKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCER 848
Query: 109 --YRPTATRG-------ACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
P RG C DV+ECE VC NGRC NT GSFRCEC G L GR
Sbjct: 849 CEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRL 908
Query: 159 CLGLKLGWGVSCQACPAQGSE-LYAVLCPEGPSKDNGGADINECTAVP-GACPHGSCENL 216
C+ ++L + C + E V P D I V ACP E+L
Sbjct: 909 CVDVRL------EPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACP--DPESL 960
Query: 217 EPGYRCICDPGYHP----DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE 272
E C G+ +D++EC + C G CRNT GSF C C G +
Sbjct: 961 EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALD 1020
Query: 273 PELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECEC 332
+ + C DIDEC I P C G C+NT G FECEC
Sbjct: 1021 AQERNCTDIDECR----------------ISPDL---------CGQGTCVNTPGSFECEC 1055
Query: 333 ELGYVLD-ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
GY + C+D VD E A LL R C + GS
Sbjct: 1056 FPGYESGFMLMKNCMD----------VD---ECARDPLLCRGGTCTNTD---GSYKCQCP 1099
Query: 392 XXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
KG A C D+DEC+LS LC G CVN G+++C C G
Sbjct: 1100 PGHELTAKGTA------CEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAG 1143
Score = 176 bits (428), Expect = 2e-43
Identities = 115/324 (35%), Positives = 143/324 (44%), Gaps = 42/324 (12%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADV 80
+C G +EG RDVDECR +C G C N+ GS+ C C+ G+ P A A C D+
Sbjct: 2350 LCPHGSGYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC+ C N++GSF C C GY C D+DEC ++ C NT G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVG 2466
Query: 141 SFRCECLPGFTLSN----DGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG---PSKDN 193
+F C C PGFT + D C G GS + C +G S +
Sbjct: 2467 AFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGS--FRCECHQGFTLVSSGH 2524
Query: 194 GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSYCAGG 252
G D+NEC P C HG C+N GYRC C G+ + C D +EC + C
Sbjct: 2525 GCEDVNECDG-PHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSA 2582
Query: 253 QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTEL 312
CRNT G F CVCP G + L C+D+DEC G RG
Sbjct: 2583 SCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG-----------RRG------------ 2619
Query: 313 ASPCDNGRCINTHGGFECECELGY 336
PC C NT GGF C C GY
Sbjct: 2620 --PCSYS-CANTPGGFLCGCPQGY 2640
Score = 174 bits (424), Expect = 5e-43
Identities = 131/455 (28%), Positives = 188/455 (41%), Gaps = 75/455 (16%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
G++ + D+DEC++ P +C+ G C NT GS+ C C PG+ + C D+DEC+
Sbjct: 1551 GFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECS 1610
Query: 85 A-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC---RNGRCHNTPG 140
S+C G C N+ G++ CVC A Y C+D+ + VC NG C N
Sbjct: 1611 THSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM----RKSVCFRHYNGTCQNELA 1666
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLG--WGVSCQACPAQGSELYAVLC-PEGPS-----KD 192
F ++ C +G W C+ACP S Y +LC + P
Sbjct: 1667 ---------FNVTRK-MCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHT 1716
Query: 193 NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYC-A 250
DI+EC +P C +G C N +RC C G++ ++ L C D+DEC +S C
Sbjct: 1717 GKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ 1776
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
C N GS+ C C G + P C G E
Sbjct: 1777 NADCINIPGSYRCKCTRGYKLSPG-------GACVGRNECR------------------- 1810
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRR----GSCWRRVVDGQC 362
E+ + C +G C++T G + C C G+ A C+D +R+ G+C + C
Sbjct: 1811 EIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNC 1870
Query: 363 EAAAPELLLR--------QECCCSVG--LAWGSXXXXXXXXXXXXXKGF-AKLDGATCRD 411
P ++ EC VG +G GF DG C D
Sbjct: 1871 -LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD 1929
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+EC A C GTC N +GS+RC CPPG + S
Sbjct: 1930 TNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQS 1964
Score = 174 bits (424), Expect = 5e-43
Identities = 126/387 (32%), Positives = 161/387 (41%), Gaps = 66/387 (17%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-----------CR----DNPRVCR 50
+C NG C N G F C C G++ C D+ + CR + V R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 51 RGRCRNTAGSYTCLCE----PG------FAPTAAGYCA---DVDEC-AADSMCKGGRCVN 96
C + CE PG P +GY A DVDEC +C G C+N
Sbjct: 2322 AECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECIN 2381
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S GSF+C C+AGY P AT C+D+DEC + C NT GSF C C G+ L DG
Sbjct: 2382 SLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Query: 157 RTCLGLK--LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGAC-PHGS 212
RTC L +CQ + CP G ++ + D +EC+A PG C HG
Sbjct: 2442 RTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGH 2501
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
C N +RC C G+ + G C D++ECD C G C+N G + C CP+G
Sbjct: 2502 CHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQ 2559
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ C D +EC PPT C + C NT GGF C
Sbjct: 2560 HSQWAQCVDENECALS---------------PPT----------CGSASCRNTLGGFRCV 2594
Query: 332 CELGYVLDATAQRCLD-----NRRGSC 353
C G+ D C D RRG C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPC 2621
Score = 171 bits (416), Expect = 4e-42
Identities = 131/471 (27%), Positives = 182/471 (38%), Gaps = 63/471 (13%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C G C N G F+C C PGY +C D+DEC + +C G C NT G+YTC+
Sbjct: 1572 GLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCV 1631
Query: 65 CEPGFAPTAAG-YCADVDECAA----DSMCKGGRCVNSEGSFQCVCEAGYRPTATR--GA 117
C + G C D+ + + C+ N C C R A
Sbjct: 1632 CPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRK-MCCCSYNIGQAWNRPCEA 1690
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
C + Q +C N PG F + G L D + G+ G
Sbjct: 1691 CPTPISPDYQILCGN----QAPG-FLTDIHTGKPLDIDECGEIPAICANGICINQI---G 1742
Query: 178 SELYAVLCPEGPSKDN---GGADINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDAD 233
S + CP G + ++ D++EC + C + C N+ YRC C GY
Sbjct: 1743 S--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPG 1800
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE----GETE 289
G C +EC + C+ G C +T GS+ C+C G + + LC DIDEC+ G
Sbjct: 1801 GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT 1860
Query: 290 THYIESDY-----------ERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
I Y GD T + C G C+NT G F C C+ G+ L
Sbjct: 1861 CKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFEL 1920
Query: 339 DATAQRCLD-NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
A + C+D N S + G C+ C C G
Sbjct: 1921 TADGKNCVDTNECLSLAGTCLPGTCQNLEGSF----RCICPPGF---------------- 1960
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
++ C D+DEC+ LC GTC N+ GS++C CPPG L G
Sbjct: 1961 -----QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006
Score = 161 bits (392), Expect = 3e-39
Identities = 143/482 (29%), Positives = 185/482 (38%), Gaps = 85/482 (17%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G+CTNG+C N DG F C C GY G C D DEC C +G C N G +
Sbjct: 2091 NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNVIGGFE 2149
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF P C D+DEC+ + + RC N+EGS+ C C AGY C DVD
Sbjct: 2150 CACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVD 2209
Query: 123 ECEE-QRVC--RNGRCHNTPGSFRCECLPGF-TLSNDGRTCLGLKLGWGVSCQACPAQGS 178
EC + Q+ C R C N G+F C C PG L G C C AQ
Sbjct: 2210 ECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC--------TDDNECHAQPD 2261
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
LC G + G+ +C P C ++ G P + +CR
Sbjct: 2262 -----LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG------PCFAEVLQTMCR 2310
Query: 238 DI---DECDMHQSYCAGG------QCR----NTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
+ E C GG +C ++ +CP G+ + E RD+DEC
Sbjct: 2311 SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE---GRDVDEC 2367
Query: 285 --------EGE--TETHYIESDYERGDIPPTFPTR-------TELASPCDNGRCINTHGG 327
GE + G P T +++ PC C NT G
Sbjct: 2368 RMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGS 2426
Query: 328 FECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
F C C GY+L+ + C D C R C+ + C C
Sbjct: 2427 FLCSCPRGYLLEEDGRTCKD--LDECTSR--QHNCQFLCVNTVGAFTCRCP--------- 2473
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDS 446
GF + A C D DEC+ C A G C NT GS+RC+C G TL S
Sbjct: 2474 -----------PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 447 TG 448
+G
Sbjct: 2522 SG 2523
Score = 155 bits (375), Expect = 4e-37
Identities = 138/468 (29%), Positives = 183/468 (39%), Gaps = 91/468 (19%)
Query: 12 CKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
CKN+ G F C+C PG G C D +EC P +C GRC NTAGS+ C C+ GF
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 71 PTAA-GYCADVDE--CAADSMCKGGRCVNSEGSF----QCVCEAG--------------- 108
P+ C D+ + C A+ + R ++S +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 109 --YRPTATRGACV-----DVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
YR G+ DVDEC +C +G C N+ GSFRC C G+T TCL
Sbjct: 2345 SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCL 2404
Query: 161 GLKLGWGVS--CQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ V C + CP G + G D++ECT+ C C N
Sbjct: 2405 DMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVN 2463
Query: 216 LEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPE 274
+ C C PG+ C D DEC C A G C NT GSF C C +G
Sbjct: 2464 TVGAFTCRCPPGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSS 2522
Query: 275 LQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECEL 334
C D++EC+G P R C +G C N GG+ C C
Sbjct: 2523 GHGCEDVNECDG--------------------PHR------CQHG-CQNQLGGYRCSCPQ 2555
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXX 393
G+ + +C+D C + C +A+ L C C G +
Sbjct: 2556 GFTQHSQWAQCVDENE--C--ALSPPTCGSASCRNTLGGFRCVCPSGFDFDQA------- 2604
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
L G C+DVDECA C+ +C NT G + C CP G
Sbjct: 2605 ----------LGG--CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQG 2639
Score = 150 bits (363), Expect = 1e-35
Identities = 94/281 (33%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
MC NG+C N DG F C+CKPG+ G C D+DEC+ P +C G C NT GS+ C C
Sbjct: 540 MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQC 598
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD-E 123
G A G C D S C G +GS C + T T+ C + +
Sbjct: 599 LGGLAVGTDGRVCVDTH---VRSTCYG---AIEKGS----CARPFPGTVTKSECCCANPD 648
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
C+ N+ F+ C G ++ DGR L V Y
Sbjct: 649 HGFGEPCQLCPAKNS-AEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRC 707
Query: 184 LCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDI 239
+C G G D++EC C +G C+N Y C C PG+H D +C+D+
Sbjct: 708 VCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDV 767
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
DEC S C G CRN AGS+TC C G+R +P C D
Sbjct: 768 DEC--LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD 806
Score = 145 bits (351), Expect = 3e-34
Identities = 82/235 (34%), Positives = 111/235 (47%), Gaps = 14/235 (5%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+CKN G F C C GY +G C+D+DEC C+ C NT G++TC C PGF
Sbjct: 2419 LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFT 2477
Query: 71 PTAAGYCADVDECAADSMCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
C D DEC+A G G C N+ GSF+C C G+ ++ C DV+EC+
Sbjct: 2478 QHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPH 2536
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL----YAVL 184
C++G C N G +RC C GFT + C+ + +S C + + +
Sbjct: 2537 RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVD-ENECALSPPTCGSASCRNTLGGFRCV 2594
Query: 185 CPEGPSKDN--GGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
CP G D GG D++EC G C + SC N G+ C C GY G C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHC 2648
Score = 123 bits (296), Expect = 1e-27
Identities = 69/186 (37%), Positives = 88/186 (47%), Gaps = 7/186 (3%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C +G C N G F C C G+ S G C DV+EC D P C+ G C+N G Y C
Sbjct: 2494 GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHG-CQNQLGGYRC 2551
Query: 64 LCEPGFAPTAA-GYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C GF + C D +ECA + C C N+ G F+CVC +G+ G C DV
Sbjct: 2552 SCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
DEC +R + C NTPG F C C G+ + G G LG+ Q P + L
Sbjct: 2612 DECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSG--LGFSPGPQDTPDKEELLS 2669
Query: 182 AVLCPE 187
+ C E
Sbjct: 2670 SEACYE 2675
Score = 113 bits (273), Expect = 9e-25
Identities = 119/476 (25%), Positives = 167/476 (35%), Gaps = 73/476 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C+N+ G F CIC GYE G C D++EC D P C G C NT GSY C
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLC 1469
Query: 64 LCEPGFAPTAAGY-CADV--DECAADSMCKGGRCVNSEGSF-------QCVCEAGYRPTA 113
C F +G C D C ++ +G ++ C C G
Sbjct: 1470 SCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGN 1529
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSF--------RCECLPGFTLSNDGRTCLGLKLG 165
C + E + +C G P C+ LPG D G
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQ-PNRITVILEDIDECQELPGLCQGGDCVNTFG---- 1584
Query: 166 WGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICD 225
C+ P + +C DI+EC+ C G+C N Y C+C
Sbjct: 1585 -SFQCECPPGYHLSEHTRICE----------DIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 226 PGY-HPDADGLCRDIDECDMHQSYCAGGQCRNT-AGSFT---CVCPE--GTRHEPELQLC 278
Y + C D+ + + Y G C+N A + T C C G + C
Sbjct: 1634 AEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEAC 1691
Query: 279 R-----DIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECE 333
D G ++ +D G P E+ + C NG CIN G F CEC
Sbjct: 1692 PTPISPDYQILCGNQAPGFL-TDIHTGK-PLDIDECGEIPAICANGICINQIGSFRCECP 1749
Query: 334 LGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXX 393
G+ ++ C D C R Q A + C C+
Sbjct: 1750 AGFNYNSILLACEDV--DECGSRESPCQQNADCINIPGSYRCKCT--------------- 1792
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+G+ G C +EC +C+ G C++T+GSY C C G + T
Sbjct: 1793 -----RGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQT 1843
Score = 75.8 bits (178), Expect = 3e-13
Identities = 48/138 (34%), Positives = 63/138 (45%), Gaps = 9/138 (6%)
Query: 316 CDNG-RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NG RCI G C C G+ + +R D R G C+ +V C+ L+ +
Sbjct: 155 CHNGGRCI---GPNRCACVYGF-MGPQCER--DYRTGPCFGQVGPEGCQHQLTGLVCTKA 208
Query: 375 -CCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVNTDG 432
CC +VG AWG +GF + C+DVDEC LC GG+CVN G
Sbjct: 209 LCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVG 268
Query: 433 SYRCDCPPGLTLDSTGTA 450
S+ C CP G L + A
Sbjct: 269 SFHCRCPVGHRLSDSSAA 286
Score = 70.5 bits (165), Expect = 1e-11
Identities = 79/272 (29%), Positives = 97/272 (35%), Gaps = 45/272 (16%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT 72
N+ G F C PG+ + + C V CR R C G C C C G
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV-VPICR---RACGEGFCSQPN---LCTCADGTLAP 110
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
+ G C+ M GG C + C+C+ GY T D R C N
Sbjct: 111 SCGVSRG-SGCSVSCM-NGGTCRGAS----CLCQKGYTGTVCGQPICD-------RGCHN 157
Query: 133 G-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
G RC G RC C+ GF G C+ G + + PEG
Sbjct: 158 GGRCI---GPNRCACVYGFM---------------GPQCERDYRTGP-CFGQVGPEGCQH 198
Query: 192 DNGGADINE--CTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSY 248
G + C A G CE L P C G+ P+ G C+D+DEC
Sbjct: 199 QLTGLVCTKALCCATVGRAWGLPCE-LCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGL 257
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
C GG C N GSF C CP G R C D
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 61.7 bits (143), Expect = 5e-09
Identities = 23/70 (32%), Positives = 35/70 (50%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C+N G F C C +G+ L ++ C D R G+C+ + G+C R++C
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQC 317
Query: 376 CCSVGLAWGS 385
CC G W +
Sbjct: 318 CCDRGRCWAA 327
Score = 55.6 bits (128), Expect = 3e-07
Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C G+ P GAC DVDEC+ +C+ G C N GSF C C G LS+ C +
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Query: 164 LG 165
G
Sbjct: 292 AG 293
Score = 41.5 bits (93), Expect = 0.006
Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
C DVDEC S C G CVN G+Y C C PG T A
Sbjct: 447 CIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQA 486
Score = 40.3 bits (90), Expect = 0.014
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 5/68 (7%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCR-NTAGSYT- 62
G+C G C N+ G F C C G+ A C D V GRC + AG YT
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDY-RAGACFSVLFGGRCAGDLAGHYTR 314
Query: 63 --CLCEPG 68
C C+ G
Sbjct: 315 RQCCCDRG 322
>AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 2 protein.
Length = 2809
Score = 308 bits (756), Expect = 3e-83
Identities = 170/465 (36%), Positives = 236/465 (50%), Gaps = 39/465 (8%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C +G C NI G + C C PG+++ C DVDEC + +C GRC NT GS+ C+C
Sbjct: 458 CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + G C D +ECA +MC G C+N +GSF C+C+ G+ C+D+DEC+
Sbjct: 518 AGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ 577
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG---WGV----SCQACPAQGS 178
+C NG C NT GSFRC+CL G + DGR C+ + +G SC A P G+
Sbjct: 578 TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC-ARPFPGT 636
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
+ C P D+G + C P S E ++ +C G DG RD
Sbjct: 637 VTKSECCCANP--DHGFGE--PCQLCPA---KNSAE-----FQALCSSGLGITTDG--RD 682
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIES 295
I+EC + CA G C N GS+ CVC G + C D+DEC + + + ++
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQN 742
Query: 296 D--YERGDIPPTFP--TRTE--------LASPCDNGRCINTHGGFECECELGYVLDATAQ 343
PP F TE L+SPC +G C N G + C+C G LD +
Sbjct: 743 SPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGT 802
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
CLD+ +G+CW ++ + +CE LR ECC ++G AWGS +GFA+
Sbjct: 803 FCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS-PCERCEIDPACARGFAR 861
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+ G TC DV+EC +C G CVNT GS+RC+CP GL LD++G
Sbjct: 862 MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 263 bits (644), Expect = 1e-69
Identities = 165/493 (33%), Positives = 222/493 (45%), Gaps = 55/493 (11%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+CT+G C+N G F C C G+ ++ C D+DECR +P +C +G C NT GS+ C
Sbjct: 995 GLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 65 CEPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG+ C DVDECA D +C+GG C N++GS++C C G+ TA AC D+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDI 1114
Query: 122 DECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQ 176
DEC +C +G+C N G+F+C C GF + D + C+ + G +
Sbjct: 1115 DECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE 1174
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
GS Y C +G S G AD++EC P C G C N+ G+RC+C G+ D
Sbjct: 1175 GS--YRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C D+DECD++ C G C NT GSF C C G C D+DEC E H
Sbjct: 1233 MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC--EVGGHN 1290
Query: 293 IESDYERGDIPPTFPTR---------------TELASP---CD-NGRCINTHGGFECECE 333
+S +IP +F R E S C G C+N G + C C
Sbjct: 1291 CDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 334 LGYVLDA----TAQRCLDN----RRGSCWRRVVDGQCEAAA---PELLLR-----QECCC 377
G+ D C +N G C +CE P R EC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ 1410
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYR 435
A+GS G+ +LD G C D++ECA C G C+NT GSY
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGY-ELDRGGGNCTDINECADPVN-CINGVCINTPGSYL 1468
Query: 436 CDCPPGLTLDSTG 448
C CP L+ +G
Sbjct: 1469 CSCPQDFELNPSG 1481
Score = 251 bits (614), Expect = 4e-66
Identities = 154/458 (33%), Positives = 196/458 (42%), Gaps = 60/458 (13%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RG-RCRNTAGSYTCLCEPGF 69
C N +G + C C GY +GA+CRDVDEC D + C RG C+N G++ C+C PG
Sbjct: 2181 CHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGM 2240
Query: 70 APTAAGY--CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
P C D +EC A +C GRCVN+ GSF+C C+ G++P+ T C D+
Sbjct: 2241 RPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDI----- 2295
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
R G C C L + + C G GWG C+ CP G+ Y LC
Sbjct: 2296 ----RQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLC 2351
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
P G G D++EC + C HG C N +RC C GY PDA C D+DEC
Sbjct: 2352 PHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQ 2411
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI-- 302
C C+NT GSF C CP G E + + C+D+DEC G
Sbjct: 2412 VPKPCT-FLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTC 2470
Query: 303 --PPTFPTRTELA----------SPCD-NGRCINTHGGFECECELGYVLDATAQRCLDNR 349
PP F + PC +G C NT G F CEC G+ L ++ C D
Sbjct: 2471 RCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED-- 2528
Query: 350 RGSCWRRVVDG--QCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA 407
C DG +C+ L C C G S A
Sbjct: 2529 VNEC-----DGPHRCQHGCQNQLGGYRCSCPQGFTQHS-------------------QWA 2564
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
C D +ECALS C +C NT G +RC CP G D
Sbjct: 2565 QCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFD 2602
Score = 236 bits (578), Expect = 1e-61
Identities = 158/481 (32%), Positives = 217/481 (45%), Gaps = 47/481 (9%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G C G C+N++G F CIC PG++ S+ C D+DEC + P +C G C N+ GS+ CL
Sbjct: 1938 GTCLPGTCQNLEGSFRCICPPGFQVQSDH--CIDIDECSEEPNLCLFGTCTNSPGSFQCL 1995
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCV--NSEGSFQCVCEAGYRPTATRGACVDV 121
C PGF + G+ C D + + + G+C + + + C RP G
Sbjct: 1996 CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWG----- 2050
Query: 122 DECEEQRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D CE +C F +PG S + G + GS
Sbjct: 2051 DPCE---LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGS- 2106
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ CP G S D G D +EC+ V C G+C N+ G+ C C G+ P C
Sbjct: 2107 -FRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCTNVIGGFECACADGFEPGLMMTC 2164
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETETHY--I 293
DIDEC ++ CA +C NT GS+ C CP G + +CRD+DEC +G+ + H +
Sbjct: 2165 EDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM 2223
Query: 294 ESDYERGDI----PP---TFPTRTE--------LASP--CDNGRCINTHGGFECECELGY 336
E G PP P E A P C NGRC+NT G F C+C+ G+
Sbjct: 2224 ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGF 2283
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEA--AAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
T C D R+G C+ V+ C + ++ E + R ECCC G WG
Sbjct: 2284 QPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPG 2343
Query: 395 XXXXKGFAKL-DGATC--RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
+ G T RDVDEC + A LCA G C+N+ GS+RC C G T D+T T
Sbjct: 2344 TSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Query: 452 L 452
L
Sbjct: 2404 L 2404
Score = 235 bits (574), Expect = 3e-61
Identities = 148/442 (33%), Positives = 197/442 (44%), Gaps = 46/442 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDEC 83
PG+ + D+DEC + P +C G C N GS+ C C GF + C DVDEC
Sbjct: 1708 PGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC 1767
Query: 84 AA-DSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPG 140
+ +S C + C+N GS++C C GY+ + GACV +EC E VC +G C +T G
Sbjct: 1768 GSRESPCQQNADCINIPGSYRCKCTRGYK-LSPGGACVGRNECREIPNVCSHGDCMDTEG 1826
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG-SELYAVLCPEGPSKDNGG--AD 197
S+ C C GF S D C+ + C + Y LC G + G D
Sbjct: 1827 SYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVD 1886
Query: 198 INECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCR 255
+ECT + G C G C N + C+C G+ ADG C D +EC C G C+
Sbjct: 1887 FDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N GSF C+CP G + + C DIDEC E
Sbjct: 1947 NLEGSFRCICPPG--FQVQSDHCIDIDECSEEPNL------------------------- 1979
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C N+ G F+C C G+VL RC D R+ C+ R G+C + C
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 376 CCS--VGLAWGSXXXXXXXXXXXXXK-----GFAKLDGA--TCRDVDECALSAELCAGGT 426
CCS G WG + G + G + DV+ECA + +C G
Sbjct: 2040 CCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGV 2099
Query: 427 CVNTDGSYRCDCPPGLTLDSTG 448
CVNTDGS+RC+CP G +LD TG
Sbjct: 2100 CVNTDGSFRCECPFGYSLDFTG 2121
Score = 225 bits (550), Expect = 3e-58
Identities = 154/461 (33%), Positives = 202/461 (43%), Gaps = 58/461 (12%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG+C+N+ G + C+C GYE+G+ G C DVDEC N +C G C+N+ GSY+C C
Sbjct: 692 VCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSC 751
Query: 66 EPGF-APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
PGF C DVDEC + S C G C N GS+ C C G R + C+D
Sbjct: 752 PPGFHFWQDTEICKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD---- 806
Query: 125 EEQRVCRNGRCHNTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
G C RCE L G +L ++ C L WG C+ C +
Sbjct: 807 -----STKGTCWLKIQESRCEVNLQGASLRSE--CCATLGAAWGSPCERCEIDPA----- 854
Query: 184 LCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDI- 239
C G ++ G D+NEC + PG CP+G C N +RC C G DA G LC D+
Sbjct: 855 -CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVR 913
Query: 240 -DECDMH--QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET----ETHY 292
+ C + + C G C C G E + C D + E + +
Sbjct: 914 LEPCFLRWDEDEC-GVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGF 972
Query: 293 IESDYERGDIPPTFPTRTE---LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
D+ G P + E C +G C NT G F C C G+ LDA + C D
Sbjct: 973 ASRDFLSG--RPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD-- 1028
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
+D +C +P+L C G + GF + C
Sbjct: 1029 --------ID-ECR-ISPDL-------CGQGTCVNTPGSFECECFPGYESGFMLM--KNC 1069
Query: 410 RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
DVDECA LC GGTC NTDGSY+C CPPG L + GTA
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTA 1110
Score = 224 bits (547), Expect = 6e-58
Identities = 150/457 (32%), Positives = 195/457 (42%), Gaps = 72/457 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C N G F C+C+ G+E ++G C D +EC C G C+N GS+ C
Sbjct: 1895 GQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRC 1954
Query: 64 LCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PGF + +C D+DEC+ + ++C G C NS GSFQC+C G+ + C D
Sbjct: 1955 ICPPGF-QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDT- 2012
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSEL 180
R C + +C F + R C + GWG C+ CP +GS
Sbjct: 2013 --------RQSFCFTRFEAGKCSVPKAFNTTKT-RCCCSKRPGEGWGDPCELCPQEGSAA 2063
Query: 181 YAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
+ LCP G P D+ D+NEC PG C +G C N + +RC C GY D G+
Sbjct: 2064 FQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGIN 2123
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL-CRDIDECEGETETHYIE 294
C D DEC + C G C N G F C C +G EP L + C DIDEC
Sbjct: 2124 CVDTDECSVGHP-CGQGTCTNVIGGFECACADG--FEPGLMMTCEDIDEC---------- 2170
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCW 354
+ P A C N T G + C C GY L C D C
Sbjct: 2171 ------SLNPLL-----CAFRCHN-----TEGSYLCTCPAGYTLREDGAMCRD--VDEC- 2211
Query: 355 RRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA--TCRDV 412
DGQ + A + EC +G G L G+ C D
Sbjct: 2212 ---ADGQQDCHARGM----ECKNLIG-----------TFACVCPPGMRPLPGSGEGCTDD 2253
Query: 413 DECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+EC +LC G CVNT GS+RCDC G T T
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLT 2290
Score = 217 bits (529), Expect = 9e-56
Identities = 143/421 (33%), Positives = 184/421 (43%), Gaps = 61/421 (14%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDEC-AADSMCKGGRC 94
+DV+EC+ P +C G CRNT GS+ C C GFA A C D+DEC + +C G C
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ GSF+C C GY C+DVDEC + +CR G C NT GS++C+C PG L
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 153 SNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG-ADINECTAVPG 206
+ G C + L G+ + C G + D G DINEC G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 207 ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
C C N E YRC C GY DG C D+DEC+ + C G C N G C+C
Sbjct: 1165 GC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLC 1223
Query: 266 PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTH 325
+G P+++ C D+DEC D+ P C +G C NT
Sbjct: 1224 YDGFMATPDMRTCVDVDEC----------------DLNPHI---------CLHGDCENTK 1258
Query: 326 GGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
G F C C+LGY++ A C D C V C++ A L + C W
Sbjct: 1259 GSFVCHCQLGYMVRKGATGCSD--VDEC--EVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTL 444
DG C D+DEC C+ G C+N GSYRC C G
Sbjct: 1315 -------------------DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 445 D 445
D
Sbjct: 1356 D 1356
Score = 210 bits (513), Expect = 8e-54
Identities = 102/272 (37%), Positives = 143/272 (52%), Gaps = 12/272 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCL 64
+C NGIC N G F C C G+ S C DVDEC C++ C N GSY C
Sbjct: 1731 ICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 65 CEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G+ + G C +EC ++C G C+++EGS+ C+C G++ +A + C+D+DE
Sbjct: 1791 CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDE 1850
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP----AQGSE 179
C+ Q C NG C N GS+ C C PGF ++++G C+ + Q C +
Sbjct: 1851 CDRQ-PCGNGTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAG 1908
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ LC +G G D NEC ++ G C G+C+NLE +RCIC PG+ +D C
Sbjct: 1909 SFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDH-C 1967
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
DIDEC + C G C N+ GSF C+CP G
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPG 1999
Score = 206 bits (503), Expect = 1e-52
Identities = 161/471 (34%), Positives = 197/471 (41%), Gaps = 70/471 (14%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C G C N+ GGFEC C G+E G C D+DEC NP +C RC NT GSY C
Sbjct: 2133 GHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDIDECSLNPLLCAF-RCHNTEGSYLC 2190
Query: 64 LCEPGFAPTAAG-YCADVDECA---ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG-AC 118
C G+ G C DVDECA D +G C N G+F CVC G RP G C
Sbjct: 2191 TCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Query: 119 VDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
D +EC Q +C NGRC NT GSFRC+C GF S C ++ G C A
Sbjct: 2251 TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG---PCFA----- 2302
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLE-PG---YRCICDPGYHPDAD 233
E+ +C S + EC G CE PG YR +C G A+
Sbjct: 2303 -EVLQTMC-RSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE 2360
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G RD+DEC M CA G+C N+ GSF C C G + C D+DEC
Sbjct: 2361 G--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDEC--------- 2409
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD-----N 348
+++ PC C NT G F C C GY+L+ + C D +
Sbjct: 2410 ----------------SQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS 2452
Query: 349 RRGSCWRRVVD--GQCEAAAPELLLRQ--------ECCCSVGL--AWGSXXXXXXXXXXX 396
R+ +C V+ G P + EC G A G
Sbjct: 2453 RQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCE 2512
Query: 397 XXKGFAKLD-GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+GF + G C DV+EC C G C N G YRC CP G T S
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHS 2561
Score = 201 bits (490), Expect = 5e-51
Identities = 150/455 (32%), Positives = 193/455 (42%), Gaps = 42/455 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ GG C+C G+ + + C DVDEC NP +C G C NT GS+
Sbjct: 1203 NPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFV 1262
Query: 63 CLCEPGF-APTAAGYCADVDEC-AADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C+ G+ A C+DVDEC C C+N GSF C C G+ C
Sbjct: 1263 CHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECH 1320
Query: 120 DVDEC--EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC-----LGLKLGWGVSCQA 172
D+DEC +E R G C N PGS+RC C GF + DG C + + Q
Sbjct: 1321 DLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQC 1378
Query: 173 CPAQGSELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A G Y C G P++D+ D++EC A C GSCENL +RCIC+ GY
Sbjct: 1379 LNAPGG--YRCECEMGFDPTEDHRACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYE 1435
Query: 230 PD-ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET 288
D G C DI+EC C G C NT GS+ C CP+ P C D
Sbjct: 1436 LDRGGGNCTDINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFL 1494
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYVLDATAQRCL- 346
ETH +RGD E+ C + G + CEL + + T R L
Sbjct: 1495 ETH------DRGD--SGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLC 1546
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
G R+ ++ EC GL G L
Sbjct: 1547 PGGEGFQPNRIT-----VILEDI---DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 407 AT--CRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
T C D+DEC+ + +C GTC NT G+Y C CP
Sbjct: 1599 HTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 196 bits (477), Expect = 2e-49
Identities = 147/440 (33%), Positives = 184/440 (41%), Gaps = 47/440 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECA 84
PG + L + +D CR +C GRC T SY C C G+ G C DVDEC
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT 454
Query: 85 ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFR 143
+ S C G CVN G++ C C G++ T TR ACVDVDEC +C GRC NT GSF+
Sbjct: 455 S-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQ 513
Query: 144 CECLPGFTLSNDGRTCLG-LKLGWGVSC--QACPAQGSELYAVLCPEGPSKDNGG---AD 197
C C GF LS DG+ C+ + C C + ++ LC G GG D
Sbjct: 514 CVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGS-FSCLCKPGFLLAPGGHYCMD 572
Query: 198 INECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-R 255
I+EC PG C +G C N E +RC C G DG +C D G C R
Sbjct: 573 IDEC-QTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCAR 631
Query: 256 NTAGSFT---CVC--PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G+ T C C P+ EP QLC + E + G
Sbjct: 632 PFPGTVTKSECCCANPDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDP 690
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPEL 369
E+ C NG C N G + C C LGY A+ + C D + + D G C+ +
Sbjct: 691 EV---CANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGS- 746
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + D C+DVDEC S C G C N
Sbjct: 747 ---YSCSCPPGFHFWQ-------------------DTEICKDVDECLSSP--CVSGVCRN 782
Query: 430 TDGSYRCDCPPGLTLDSTGT 449
GSY C C PG LD +GT
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT 802
Score = 193 bits (471), Expect = 9e-49
Identities = 109/272 (40%), Positives = 138/272 (50%), Gaps = 14/272 (5%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G C N G F C C+ GY + C D+DEC P+ C C+NT GS+ C C
Sbjct: 2373 LCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSC 2431
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DEC + CVN+ G+F C C G+ T AC D DEC
Sbjct: 2432 PRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGF--TQHHQACFDNDEC 2489
Query: 125 EEQ-RVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQ-ACPAQGSEL 180
Q C +G CHNTPGSFRCEC GFTL + G C + G CQ C Q
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGG- 2548
Query: 181 YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLC 236
Y CP+G ++ + A D NEC P C SC N G+RC+C G+ D A G C
Sbjct: 2549 YRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGC 2608
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
+D+DEC + C+ C NT G F C CP+G
Sbjct: 2609 QDVDECAGRRGPCS-YSCANTPGGFLCGCPQG 2639
Score = 187 bits (456), Expect = 6e-47
Identities = 155/470 (32%), Positives = 194/470 (41%), Gaps = 88/470 (18%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C NG C+N G + C C PG+ + +C+DVDEC +P C G CRN AGSYT
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYT 788
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRC-VNSEGS---FQCVCEAG--------- 108
C C PG +G +C D + + RC VN +G+ +C G
Sbjct: 789 CKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCER 848
Query: 109 --YRPTATRG-------ACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
P RG C DV+ECE VC NGRC NT GSFRCEC G L GR
Sbjct: 849 CEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRL 908
Query: 159 CLGLKLGWGVSCQACPAQGSE-LYAVLCPEGPSKDNGGADINECTAVP-GACPHGSCENL 216
C+ ++L + C + E V P D I V ACP E+L
Sbjct: 909 CVDVRL------EPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACP--DPESL 960
Query: 217 EPGYRCICDPGYHP----DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE 272
E C G+ +D++EC + C G CRNT GSF C C G +
Sbjct: 961 EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALD 1020
Query: 273 PELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECEC 332
+ + C DIDEC I P C G C+NT G FECEC
Sbjct: 1021 AQERNCTDIDECR----------------ISPDL---------CGQGTCVNTPGSFECEC 1055
Query: 333 ELGYVLD-ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
GY + C+D VD E A LL R C + GS
Sbjct: 1056 FPGYESGFMLMKNCMD----------VD---ECARDPLLCRGGTCTNTD---GSYKCQCP 1099
Query: 392 XXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
KG A C D+DEC+LS LC G CVN G+++C C G
Sbjct: 1100 PGHELTAKGTA------CEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAG 1143
Score = 176 bits (428), Expect = 2e-43
Identities = 115/324 (35%), Positives = 143/324 (44%), Gaps = 42/324 (12%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADV 80
+C G +EG RDVDECR +C G C N+ GS+ C C+ G+ P A A C D+
Sbjct: 2350 LCPHGSGYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC+ C N++GSF C C GY C D+DEC ++ C NT G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVG 2466
Query: 141 SFRCECLPGFTLSN----DGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG---PSKDN 193
+F C C PGFT + D C G GS + C +G S +
Sbjct: 2467 AFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGS--FRCECHQGFTLVSSGH 2524
Query: 194 GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSYCAGG 252
G D+NEC P C HG C+N GYRC C G+ + C D +EC + C
Sbjct: 2525 GCEDVNECDG-PHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSA 2582
Query: 253 QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTEL 312
CRNT G F CVCP G + L C+D+DEC G RG
Sbjct: 2583 SCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG-----------RRG------------ 2619
Query: 313 ASPCDNGRCINTHGGFECECELGY 336
PC C NT GGF C C GY
Sbjct: 2620 --PCSYS-CANTPGGFLCGCPQGY 2640
Score = 174 bits (424), Expect = 5e-43
Identities = 131/455 (28%), Positives = 188/455 (41%), Gaps = 75/455 (16%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
G++ + D+DEC++ P +C+ G C NT GS+ C C PG+ + C D+DEC+
Sbjct: 1551 GFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECS 1610
Query: 85 A-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC---RNGRCHNTPG 140
S+C G C N+ G++ CVC A Y C+D+ + VC NG C N
Sbjct: 1611 THSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM----RKSVCFRHYNGTCQNELA 1666
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLG--WGVSCQACPAQGSELYAVLC-PEGPS-----KD 192
F ++ C +G W C+ACP S Y +LC + P
Sbjct: 1667 ---------FNVTRK-MCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHT 1716
Query: 193 NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYC-A 250
DI+EC +P C +G C N +RC C G++ ++ L C D+DEC +S C
Sbjct: 1717 GKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ 1776
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
C N GS+ C C G + P C G E
Sbjct: 1777 NADCINIPGSYRCKCTRGYKLSPG-------GACVGRNECR------------------- 1810
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRR----GSCWRRVVDGQC 362
E+ + C +G C++T G + C C G+ A C+D +R+ G+C + C
Sbjct: 1811 EIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNC 1870
Query: 363 EAAAPELLLR--------QECCCSVG--LAWGSXXXXXXXXXXXXXKGF-AKLDGATCRD 411
P ++ EC VG +G GF DG C D
Sbjct: 1871 -LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD 1929
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+EC A C GTC N +GS+RC CPPG + S
Sbjct: 1930 TNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQS 1964
Score = 174 bits (424), Expect = 5e-43
Identities = 126/387 (32%), Positives = 161/387 (41%), Gaps = 66/387 (17%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-----------CR----DNPRVCR 50
+C NG C N G F C C G++ C D+ + CR + V R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 51 RGRCRNTAGSYTCLCE----PG------FAPTAAGYCA---DVDEC-AADSMCKGGRCVN 96
C + CE PG P +GY A DVDEC +C G C+N
Sbjct: 2322 AECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECIN 2381
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S GSF+C C+AGY P AT C+D+DEC + C NT GSF C C G+ L DG
Sbjct: 2382 SLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Query: 157 RTCLGLK--LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGAC-PHGS 212
RTC L +CQ + CP G ++ + D +EC+A PG C HG
Sbjct: 2442 RTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGH 2501
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
C N +RC C G+ + G C D++ECD C G C+N G + C CP+G
Sbjct: 2502 CHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQ 2559
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ C D +EC PPT C + C NT GGF C
Sbjct: 2560 HSQWAQCVDENECALS---------------PPT----------CGSASCRNTLGGFRCV 2594
Query: 332 CELGYVLDATAQRCLD-----NRRGSC 353
C G+ D C D RRG C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPC 2621
Score = 171 bits (416), Expect = 4e-42
Identities = 131/471 (27%), Positives = 182/471 (38%), Gaps = 63/471 (13%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C G C N G F+C C PGY +C D+DEC + +C G C NT G+YTC+
Sbjct: 1572 GLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCV 1631
Query: 65 CEPGFAPTAAG-YCADVDECAA----DSMCKGGRCVNSEGSFQCVCEAGYRPTATR--GA 117
C + G C D+ + + C+ N C C R A
Sbjct: 1632 CPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRK-MCCCSYNIGQAWNRPCEA 1690
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
C + Q +C N PG F + G L D + G+ G
Sbjct: 1691 CPTPISPDYQILCGN----QAPG-FLTDIHTGKPLDIDECGEIPAICANGICINQI---G 1742
Query: 178 SELYAVLCPEGPSKDN---GGADINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDAD 233
S + CP G + ++ D++EC + C + C N+ YRC C GY
Sbjct: 1743 S--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPG 1800
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE----GETE 289
G C +EC + C+ G C +T GS+ C+C G + + LC DIDEC+ G
Sbjct: 1801 GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT 1860
Query: 290 THYIESDY-----------ERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
I Y GD T + C G C+NT G F C C+ G+ L
Sbjct: 1861 CKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFEL 1920
Query: 339 DATAQRCLD-NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
A + C+D N S + G C+ C C G
Sbjct: 1921 TADGKNCVDTNECLSLAGTCLPGTCQNLEGSF----RCICPPGF---------------- 1960
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
++ C D+DEC+ LC GTC N+ GS++C CPPG L G
Sbjct: 1961 -----QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006
Score = 161 bits (392), Expect = 3e-39
Identities = 143/482 (29%), Positives = 185/482 (38%), Gaps = 85/482 (17%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G+CTNG+C N DG F C C GY G C D DEC C +G C N G +
Sbjct: 2091 NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNVIGGFE 2149
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF P C D+DEC+ + + RC N+EGS+ C C AGY C DVD
Sbjct: 2150 CACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVD 2209
Query: 123 ECEE-QRVC--RNGRCHNTPGSFRCECLPGF-TLSNDGRTCLGLKLGWGVSCQACPAQGS 178
EC + Q+ C R C N G+F C C PG L G C C AQ
Sbjct: 2210 ECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC--------TDDNECHAQPD 2261
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
LC G + G+ +C P C ++ G P + +CR
Sbjct: 2262 -----LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG------PCFAEVLQTMCR 2310
Query: 238 DI---DECDMHQSYCAGG------QCR----NTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
+ E C GG +C ++ +CP G+ + E RD+DEC
Sbjct: 2311 SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE---GRDVDEC 2367
Query: 285 --------EGE--TETHYIESDYERGDIPPTFPTR-------TELASPCDNGRCINTHGG 327
GE + G P T +++ PC C NT G
Sbjct: 2368 RMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGS 2426
Query: 328 FECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
F C C GY+L+ + C D C R C+ + C C
Sbjct: 2427 FLCSCPRGYLLEEDGRTCKD--LDECTSR--QHNCQFLCVNTVGAFTCRCP--------- 2473
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDS 446
GF + A C D DEC+ C A G C NT GS+RC+C G TL S
Sbjct: 2474 -----------PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 447 TG 448
+G
Sbjct: 2522 SG 2523
Score = 155 bits (375), Expect = 4e-37
Identities = 138/468 (29%), Positives = 183/468 (39%), Gaps = 91/468 (19%)
Query: 12 CKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
CKN+ G F C+C PG G C D +EC P +C GRC NTAGS+ C C+ GF
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 71 PTAA-GYCADVDE--CAADSMCKGGRCVNSEGSF----QCVCEAG--------------- 108
P+ C D+ + C A+ + R ++S +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 109 --YRPTATRGACV-----DVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
YR G+ DVDEC +C +G C N+ GSFRC C G+T TCL
Sbjct: 2345 SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCL 2404
Query: 161 GLKLGWGVS--CQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ V C + CP G + G D++ECT+ C C N
Sbjct: 2405 DMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVN 2463
Query: 216 LEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPE 274
+ C C PG+ C D DEC C A G C NT GSF C C +G
Sbjct: 2464 TVGAFTCRCPPGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSS 2522
Query: 275 LQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECEL 334
C D++EC+G P R C +G C N GG+ C C
Sbjct: 2523 GHGCEDVNECDG--------------------PHR------CQHG-CQNQLGGYRCSCPQ 2555
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXX 393
G+ + +C+D C + C +A+ L C C G +
Sbjct: 2556 GFTQHSQWAQCVDENE--C--ALSPPTCGSASCRNTLGGFRCVCPSGFDFDQA------- 2604
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
L G C+DVDECA C+ +C NT G + C CP G
Sbjct: 2605 ----------LGG--CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQG 2639
Score = 150 bits (363), Expect = 1e-35
Identities = 94/281 (33%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
MC NG+C N DG F C+CKPG+ G C D+DEC+ P +C G C NT GS+ C C
Sbjct: 540 MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQC 598
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD-E 123
G A G C D S C G +GS C + T T+ C + +
Sbjct: 599 LGGLAVGTDGRVCVDTH---VRSTCYG---AIEKGS----CARPFPGTVTKSECCCANPD 648
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
C+ N+ F+ C G ++ DGR L V Y
Sbjct: 649 HGFGEPCQLCPAKNS-AEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRC 707
Query: 184 LCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDI 239
+C G G D++EC C +G C+N Y C C PG+H D +C+D+
Sbjct: 708 VCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDV 767
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
DEC S C G CRN AGS+TC C G+R +P C D
Sbjct: 768 DEC--LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD 806
Score = 145 bits (351), Expect = 3e-34
Identities = 82/235 (34%), Positives = 111/235 (47%), Gaps = 14/235 (5%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+CKN G F C C GY +G C+D+DEC C+ C NT G++TC C PGF
Sbjct: 2419 LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFT 2477
Query: 71 PTAAGYCADVDECAADSMCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
C D DEC+A G G C N+ GSF+C C G+ ++ C DV+EC+
Sbjct: 2478 QHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPH 2536
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL----YAVL 184
C++G C N G +RC C GFT + C+ + +S C + + +
Sbjct: 2537 RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVD-ENECALSPPTCGSASCRNTLGGFRCV 2594
Query: 185 CPEGPSKDN--GGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
CP G D GG D++EC G C + SC N G+ C C GY G C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHC 2648
Score = 123 bits (296), Expect = 1e-27
Identities = 69/186 (37%), Positives = 88/186 (47%), Gaps = 7/186 (3%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C +G C N G F C C G+ S G C DV+EC D P C+ G C+N G Y C
Sbjct: 2494 GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHG-CQNQLGGYRC 2551
Query: 64 LCEPGFAPTAA-GYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C GF + C D +ECA + C C N+ G F+CVC +G+ G C DV
Sbjct: 2552 SCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
DEC +R + C NTPG F C C G+ + G G LG+ Q P + L
Sbjct: 2612 DECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSG--LGFSPGPQDTPDKEELLS 2669
Query: 182 AVLCPE 187
+ C E
Sbjct: 2670 SEACYE 2675
Score = 113 bits (273), Expect = 9e-25
Identities = 119/476 (25%), Positives = 167/476 (35%), Gaps = 73/476 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C+N+ G F CIC GYE G C D++EC D P C G C NT GSY C
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLC 1469
Query: 64 LCEPGFAPTAAGY-CADV--DECAADSMCKGGRCVNSEGSF-------QCVCEAGYRPTA 113
C F +G C D C ++ +G ++ C C G
Sbjct: 1470 SCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGN 1529
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSF--------RCECLPGFTLSNDGRTCLGLKLG 165
C + E + +C G P C+ LPG D G
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQ-PNRITVILEDIDECQELPGLCQGGDCVNTFG---- 1584
Query: 166 WGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICD 225
C+ P + +C DI+EC+ C G+C N Y C+C
Sbjct: 1585 -SFQCECPPGYHLSEHTRICE----------DIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 226 PGY-HPDADGLCRDIDECDMHQSYCAGGQCRNT-AGSFT---CVCPE--GTRHEPELQLC 278
Y + C D+ + + Y G C+N A + T C C G + C
Sbjct: 1634 AEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEAC 1691
Query: 279 R-----DIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECE 333
D G ++ +D G P E+ + C NG CIN G F CEC
Sbjct: 1692 PTPISPDYQILCGNQAPGFL-TDIHTGK-PLDIDECGEIPAICANGICINQIGSFRCECP 1749
Query: 334 LGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXX 393
G+ ++ C D C R Q A + C C+
Sbjct: 1750 AGFNYNSILLACEDV--DECGSRESPCQQNADCINIPGSYRCKCT--------------- 1792
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+G+ G C +EC +C+ G C++T+GSY C C G + T
Sbjct: 1793 -----RGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQT 1843
Score = 75.8 bits (178), Expect = 3e-13
Identities = 48/138 (34%), Positives = 63/138 (45%), Gaps = 9/138 (6%)
Query: 316 CDNG-RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NG RCI G C C G+ + +R D R G C+ +V C+ L+ +
Sbjct: 155 CHNGGRCI---GPNRCACVYGF-MGPQCER--DYRTGPCFGQVGPEGCQHQLTGLVCTKA 208
Query: 375 -CCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVNTDG 432
CC +VG AWG +GF + C+DVDEC LC GG+CVN G
Sbjct: 209 LCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVG 268
Query: 433 SYRCDCPPGLTLDSTGTA 450
S+ C CP G L + A
Sbjct: 269 SFHCRCPVGHRLSDSSAA 286
Score = 70.5 bits (165), Expect = 1e-11
Identities = 79/272 (29%), Positives = 97/272 (35%), Gaps = 45/272 (16%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT 72
N+ G F C PG+ + + C V CR R C G C C C G
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV-VPICR---RACGEGFCSQPN---LCTCADGTLAP 110
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
+ G C+ M GG C + C+C+ GY T D R C N
Sbjct: 111 SCGVSRG-SGCSVSCM-NGGTCRGAS----CLCQKGYTGTVCGQPICD-------RGCHN 157
Query: 133 G-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
G RC G RC C+ GF G C+ G + + PEG
Sbjct: 158 GGRCI---GPNRCACVYGFM---------------GPQCERDYRTGP-CFGQVGPEGCQH 198
Query: 192 DNGGADINE--CTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSY 248
G + C A G CE L P C G+ P+ G C+D+DEC
Sbjct: 199 QLTGLVCTKALCCATVGRAWGLPCE-LCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGL 257
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
C GG C N GSF C CP G R C D
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 61.7 bits (143), Expect = 5e-09
Identities = 23/70 (32%), Positives = 35/70 (50%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C+N G F C C +G+ L ++ C D R G+C+ + G+C R++C
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQC 317
Query: 376 CCSVGLAWGS 385
CC G W +
Sbjct: 318 CCDRGRCWAA 327
Score = 55.6 bits (128), Expect = 3e-07
Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C G+ P GAC DVDEC+ +C+ G C N GSF C C G LS+ C +
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Query: 164 LG 165
G
Sbjct: 292 AG 293
Score = 41.5 bits (93), Expect = 0.006
Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
C DVDEC S C G CVN G+Y C C PG T A
Sbjct: 447 CIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQA 486
Score = 40.3 bits (90), Expect = 0.014
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 5/68 (7%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCR-NTAGSYT- 62
G+C G C N+ G F C C G+ A C D V GRC + AG YT
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDY-RAGACFSVLFGGRCAGDLAGHYTR 314
Query: 63 --CLCEPG 68
C C+ G
Sbjct: 315 RQCCCDRG 322
>AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 1 protein.
Length = 2809
Score = 308 bits (756), Expect = 3e-83
Identities = 170/465 (36%), Positives = 236/465 (50%), Gaps = 39/465 (8%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C +G C NI G + C C PG+++ C DVDEC + +C GRC NT GS+ C+C
Sbjct: 458 CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + G C D +ECA +MC G C+N +GSF C+C+ G+ C+D+DEC+
Sbjct: 518 AGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ 577
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG---WGV----SCQACPAQGS 178
+C NG C NT GSFRC+CL G + DGR C+ + +G SC A P G+
Sbjct: 578 TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC-ARPFPGT 636
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
+ C P D+G + C P S E ++ +C G DG RD
Sbjct: 637 VTKSECCCANP--DHGFGE--PCQLCPA---KNSAE-----FQALCSSGLGITTDG--RD 682
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIES 295
I+EC + CA G C N GS+ CVC G + C D+DEC + + + ++
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQN 742
Query: 296 D--YERGDIPPTFP--TRTE--------LASPCDNGRCINTHGGFECECELGYVLDATAQ 343
PP F TE L+SPC +G C N G + C+C G LD +
Sbjct: 743 SPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGT 802
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
CLD+ +G+CW ++ + +CE LR ECC ++G AWGS +GFA+
Sbjct: 803 FCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS-PCERCEIDPACARGFAR 861
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+ G TC DV+EC +C G CVNT GS+RC+CP GL LD++G
Sbjct: 862 MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 263 bits (644), Expect = 1e-69
Identities = 165/493 (33%), Positives = 222/493 (45%), Gaps = 55/493 (11%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+CT+G C+N G F C C G+ ++ C D+DECR +P +C +G C NT GS+ C
Sbjct: 995 GLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 65 CEPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG+ C DVDECA D +C+GG C N++GS++C C G+ TA AC D+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDI 1114
Query: 122 DECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQ 176
DEC +C +G+C N G+F+C C GF + D + C+ + G +
Sbjct: 1115 DECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE 1174
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
GS Y C +G S G AD++EC P C G C N+ G+RC+C G+ D
Sbjct: 1175 GS--YRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C D+DECD++ C G C NT GSF C C G C D+DEC E H
Sbjct: 1233 MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC--EVGGHN 1290
Query: 293 IESDYERGDIPPTFPTR---------------TELASP---CD-NGRCINTHGGFECECE 333
+S +IP +F R E S C G C+N G + C C
Sbjct: 1291 CDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 334 LGYVLDA----TAQRCLDN----RRGSCWRRVVDGQCEAAA---PELLLR-----QECCC 377
G+ D C +N G C +CE P R EC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ 1410
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYR 435
A+GS G+ +LD G C D++ECA C G C+NT GSY
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGY-ELDRGGGNCTDINECADPVN-CINGVCINTPGSYL 1468
Query: 436 CDCPPGLTLDSTG 448
C CP L+ +G
Sbjct: 1469 CSCPQDFELNPSG 1481
Score = 251 bits (614), Expect = 4e-66
Identities = 154/458 (33%), Positives = 196/458 (42%), Gaps = 60/458 (13%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RG-RCRNTAGSYTCLCEPGF 69
C N +G + C C GY +GA+CRDVDEC D + C RG C+N G++ C+C PG
Sbjct: 2181 CHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGM 2240
Query: 70 APTAAGY--CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
P C D +EC A +C GRCVN+ GSF+C C+ G++P+ T C D+
Sbjct: 2241 RPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDI----- 2295
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
R G C C L + + C G GWG C+ CP G+ Y LC
Sbjct: 2296 ----RQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLC 2351
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
P G G D++EC + C HG C N +RC C GY PDA C D+DEC
Sbjct: 2352 PHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQ 2411
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI-- 302
C C+NT GSF C CP G E + + C+D+DEC G
Sbjct: 2412 VPKPCT-FLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTC 2470
Query: 303 --PPTFPTRTELA----------SPCD-NGRCINTHGGFECECELGYVLDATAQRCLDNR 349
PP F + PC +G C NT G F CEC G+ L ++ C D
Sbjct: 2471 RCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED-- 2528
Query: 350 RGSCWRRVVDG--QCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA 407
C DG +C+ L C C G S A
Sbjct: 2529 VNEC-----DGPHRCQHGCQNQLGGYRCSCPQGFTQHS-------------------QWA 2564
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
C D +ECALS C +C NT G +RC CP G D
Sbjct: 2565 QCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFD 2602
Score = 236 bits (578), Expect = 1e-61
Identities = 158/481 (32%), Positives = 217/481 (45%), Gaps = 47/481 (9%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G C G C+N++G F CIC PG++ S+ C D+DEC + P +C G C N+ GS+ CL
Sbjct: 1938 GTCLPGTCQNLEGSFRCICPPGFQVQSDH--CIDIDECSEEPNLCLFGTCTNSPGSFQCL 1995
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCV--NSEGSFQCVCEAGYRPTATRGACVDV 121
C PGF + G+ C D + + + G+C + + + C RP G
Sbjct: 1996 CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWG----- 2050
Query: 122 DECEEQRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D CE +C F +PG S + G + GS
Sbjct: 2051 DPCE---LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGS- 2106
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ CP G S D G D +EC+ V C G+C N+ G+ C C G+ P C
Sbjct: 2107 -FRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCTNVIGGFECACADGFEPGLMMTC 2164
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETETHY--I 293
DIDEC ++ CA +C NT GS+ C CP G + +CRD+DEC +G+ + H +
Sbjct: 2165 EDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM 2223
Query: 294 ESDYERGDI----PP---TFPTRTE--------LASP--CDNGRCINTHGGFECECELGY 336
E G PP P E A P C NGRC+NT G F C+C+ G+
Sbjct: 2224 ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGF 2283
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEA--AAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
T C D R+G C+ V+ C + ++ E + R ECCC G WG
Sbjct: 2284 QPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPG 2343
Query: 395 XXXXKGFAKL-DGATC--RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
+ G T RDVDEC + A LCA G C+N+ GS+RC C G T D+T T
Sbjct: 2344 TSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Query: 452 L 452
L
Sbjct: 2404 L 2404
Score = 235 bits (574), Expect = 3e-61
Identities = 148/442 (33%), Positives = 197/442 (44%), Gaps = 46/442 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDEC 83
PG+ + D+DEC + P +C G C N GS+ C C GF + C DVDEC
Sbjct: 1708 PGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC 1767
Query: 84 AA-DSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPG 140
+ +S C + C+N GS++C C GY+ + GACV +EC E VC +G C +T G
Sbjct: 1768 GSRESPCQQNADCINIPGSYRCKCTRGYK-LSPGGACVGRNECREIPNVCSHGDCMDTEG 1826
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG-SELYAVLCPEGPSKDNGG--AD 197
S+ C C GF S D C+ + C + Y LC G + G D
Sbjct: 1827 SYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVD 1886
Query: 198 INECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCR 255
+ECT + G C G C N + C+C G+ ADG C D +EC C G C+
Sbjct: 1887 FDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N GSF C+CP G + + C DIDEC E
Sbjct: 1947 NLEGSFRCICPPG--FQVQSDHCIDIDECSEEPNL------------------------- 1979
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C N+ G F+C C G+VL RC D R+ C+ R G+C + C
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 376 CCS--VGLAWGSXXXXXXXXXXXXXK-----GFAKLDGA--TCRDVDECALSAELCAGGT 426
CCS G WG + G + G + DV+ECA + +C G
Sbjct: 2040 CCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGV 2099
Query: 427 CVNTDGSYRCDCPPGLTLDSTG 448
CVNTDGS+RC+CP G +LD TG
Sbjct: 2100 CVNTDGSFRCECPFGYSLDFTG 2121
Score = 225 bits (550), Expect = 3e-58
Identities = 154/461 (33%), Positives = 202/461 (43%), Gaps = 58/461 (12%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG+C+N+ G + C+C GYE+G+ G C DVDEC N +C G C+N+ GSY+C C
Sbjct: 692 VCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSC 751
Query: 66 EPGF-APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
PGF C DVDEC + S C G C N GS+ C C G R + C+D
Sbjct: 752 PPGFHFWQDTEICKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD---- 806
Query: 125 EEQRVCRNGRCHNTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
G C RCE L G +L ++ C L WG C+ C +
Sbjct: 807 -----STKGTCWLKIQESRCEVNLQGASLRSE--CCATLGAAWGSPCERCEIDPA----- 854
Query: 184 LCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDI- 239
C G ++ G D+NEC + PG CP+G C N +RC C G DA G LC D+
Sbjct: 855 -CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVR 913
Query: 240 -DECDMH--QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET----ETHY 292
+ C + + C G C C G E + C D + E + +
Sbjct: 914 LEPCFLRWDEDEC-GVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGF 972
Query: 293 IESDYERGDIPPTFPTRTE---LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
D+ G P + E C +G C NT G F C C G+ LDA + C D
Sbjct: 973 ASRDFLSG--RPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD-- 1028
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
+D +C +P+L C G + GF + C
Sbjct: 1029 --------ID-ECR-ISPDL-------CGQGTCVNTPGSFECECFPGYESGFMLM--KNC 1069
Query: 410 RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
DVDECA LC GGTC NTDGSY+C CPPG L + GTA
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTA 1110
Score = 224 bits (547), Expect = 6e-58
Identities = 150/457 (32%), Positives = 195/457 (42%), Gaps = 72/457 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C N G F C+C+ G+E ++G C D +EC C G C+N GS+ C
Sbjct: 1895 GQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRC 1954
Query: 64 LCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PGF + +C D+DEC+ + ++C G C NS GSFQC+C G+ + C D
Sbjct: 1955 ICPPGF-QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDT- 2012
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSEL 180
R C + +C F + R C + GWG C+ CP +GS
Sbjct: 2013 --------RQSFCFTRFEAGKCSVPKAFNTTKT-RCCCSKRPGEGWGDPCELCPQEGSAA 2063
Query: 181 YAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
+ LCP G P D+ D+NEC PG C +G C N + +RC C GY D G+
Sbjct: 2064 FQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGIN 2123
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL-CRDIDECEGETETHYIE 294
C D DEC + C G C N G F C C +G EP L + C DIDEC
Sbjct: 2124 CVDTDECSVGHP-CGQGTCTNVIGGFECACADG--FEPGLMMTCEDIDEC---------- 2170
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCW 354
+ P A C N T G + C C GY L C D C
Sbjct: 2171 ------SLNPLL-----CAFRCHN-----TEGSYLCTCPAGYTLREDGAMCRD--VDEC- 2211
Query: 355 RRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA--TCRDV 412
DGQ + A + EC +G G L G+ C D
Sbjct: 2212 ---ADGQQDCHARGM----ECKNLIG-----------TFACVCPPGMRPLPGSGEGCTDD 2253
Query: 413 DECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+EC +LC G CVNT GS+RCDC G T T
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLT 2290
Score = 217 bits (529), Expect = 9e-56
Identities = 143/421 (33%), Positives = 184/421 (43%), Gaps = 61/421 (14%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDEC-AADSMCKGGRC 94
+DV+EC+ P +C G CRNT GS+ C C GFA A C D+DEC + +C G C
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ GSF+C C GY C+DVDEC + +CR G C NT GS++C+C PG L
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 153 SNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG-ADINECTAVPG 206
+ G C + L G+ + C G + D G DINEC G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 207 ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
C C N E YRC C GY DG C D+DEC+ + C G C N G C+C
Sbjct: 1165 GC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLC 1223
Query: 266 PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTH 325
+G P+++ C D+DEC D+ P C +G C NT
Sbjct: 1224 YDGFMATPDMRTCVDVDEC----------------DLNPHI---------CLHGDCENTK 1258
Query: 326 GGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
G F C C+LGY++ A C D C V C++ A L + C W
Sbjct: 1259 GSFVCHCQLGYMVRKGATGCSD--VDEC--EVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTL 444
DG C D+DEC C+ G C+N GSYRC C G
Sbjct: 1315 -------------------DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 445 D 445
D
Sbjct: 1356 D 1356
Score = 210 bits (513), Expect = 8e-54
Identities = 102/272 (37%), Positives = 143/272 (52%), Gaps = 12/272 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCL 64
+C NGIC N G F C C G+ S C DVDEC C++ C N GSY C
Sbjct: 1731 ICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 65 CEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G+ + G C +EC ++C G C+++EGS+ C+C G++ +A + C+D+DE
Sbjct: 1791 CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDE 1850
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP----AQGSE 179
C+ Q C NG C N GS+ C C PGF ++++G C+ + Q C +
Sbjct: 1851 CDRQ-PCGNGTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAG 1908
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ LC +G G D NEC ++ G C G+C+NLE +RCIC PG+ +D C
Sbjct: 1909 SFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDH-C 1967
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
DIDEC + C G C N+ GSF C+CP G
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPG 1999
Score = 206 bits (503), Expect = 1e-52
Identities = 161/471 (34%), Positives = 197/471 (41%), Gaps = 70/471 (14%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C G C N+ GGFEC C G+E G C D+DEC NP +C RC NT GSY C
Sbjct: 2133 GHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDIDECSLNPLLCAF-RCHNTEGSYLC 2190
Query: 64 LCEPGFAPTAAG-YCADVDECA---ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG-AC 118
C G+ G C DVDECA D +G C N G+F CVC G RP G C
Sbjct: 2191 TCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Query: 119 VDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
D +EC Q +C NGRC NT GSFRC+C GF S C ++ G C A
Sbjct: 2251 TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG---PCFA----- 2302
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLE-PG---YRCICDPGYHPDAD 233
E+ +C S + EC G CE PG YR +C G A+
Sbjct: 2303 -EVLQTMC-RSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE 2360
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G RD+DEC M CA G+C N+ GSF C C G + C D+DEC
Sbjct: 2361 G--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDEC--------- 2409
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD-----N 348
+++ PC C NT G F C C GY+L+ + C D +
Sbjct: 2410 ----------------SQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS 2452
Query: 349 RRGSCWRRVVD--GQCEAAAPELLLRQ--------ECCCSVGL--AWGSXXXXXXXXXXX 396
R+ +C V+ G P + EC G A G
Sbjct: 2453 RQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCE 2512
Query: 397 XXKGFAKLD-GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+GF + G C DV+EC C G C N G YRC CP G T S
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHS 2561
Score = 201 bits (490), Expect = 5e-51
Identities = 150/455 (32%), Positives = 193/455 (42%), Gaps = 42/455 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ GG C+C G+ + + C DVDEC NP +C G C NT GS+
Sbjct: 1203 NPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFV 1262
Query: 63 CLCEPGF-APTAAGYCADVDEC-AADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C+ G+ A C+DVDEC C C+N GSF C C G+ C
Sbjct: 1263 CHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECH 1320
Query: 120 DVDEC--EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC-----LGLKLGWGVSCQA 172
D+DEC +E R G C N PGS+RC C GF + DG C + + Q
Sbjct: 1321 DLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQC 1378
Query: 173 CPAQGSELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A G Y C G P++D+ D++EC A C GSCENL +RCIC+ GY
Sbjct: 1379 LNAPGG--YRCECEMGFDPTEDHRACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYE 1435
Query: 230 PD-ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET 288
D G C DI+EC C G C NT GS+ C CP+ P C D
Sbjct: 1436 LDRGGGNCTDINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFL 1494
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYVLDATAQRCL- 346
ETH +RGD E+ C + G + CEL + + T R L
Sbjct: 1495 ETH------DRGD--SGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLC 1546
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
G R+ ++ EC GL G L
Sbjct: 1547 PGGEGFQPNRIT-----VILEDI---DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 407 AT--CRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
T C D+DEC+ + +C GTC NT G+Y C CP
Sbjct: 1599 HTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 196 bits (477), Expect = 2e-49
Identities = 147/440 (33%), Positives = 184/440 (41%), Gaps = 47/440 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECA 84
PG + L + +D CR +C GRC T SY C C G+ G C DVDEC
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT 454
Query: 85 ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFR 143
+ S C G CVN G++ C C G++ T TR ACVDVDEC +C GRC NT GSF+
Sbjct: 455 S-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQ 513
Query: 144 CECLPGFTLSNDGRTCLG-LKLGWGVSC--QACPAQGSELYAVLCPEGPSKDNGG---AD 197
C C GF LS DG+ C+ + C C + ++ LC G GG D
Sbjct: 514 CVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGS-FSCLCKPGFLLAPGGHYCMD 572
Query: 198 INECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-R 255
I+EC PG C +G C N E +RC C G DG +C D G C R
Sbjct: 573 IDEC-QTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCAR 631
Query: 256 NTAGSFT---CVC--PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G+ T C C P+ EP QLC + E + G
Sbjct: 632 PFPGTVTKSECCCANPDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDP 690
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPEL 369
E+ C NG C N G + C C LGY A+ + C D + + D G C+ +
Sbjct: 691 EV---CANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGS- 746
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + D C+DVDEC S C G C N
Sbjct: 747 ---YSCSCPPGFHFWQ-------------------DTEICKDVDECLSSP--CVSGVCRN 782
Query: 430 TDGSYRCDCPPGLTLDSTGT 449
GSY C C PG LD +GT
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT 802
Score = 193 bits (471), Expect = 9e-49
Identities = 109/272 (40%), Positives = 138/272 (50%), Gaps = 14/272 (5%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G C N G F C C+ GY + C D+DEC P+ C C+NT GS+ C C
Sbjct: 2373 LCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSC 2431
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DEC + CVN+ G+F C C G+ T AC D DEC
Sbjct: 2432 PRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGF--TQHHQACFDNDEC 2489
Query: 125 EEQ-RVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQ-ACPAQGSEL 180
Q C +G CHNTPGSFRCEC GFTL + G C + G CQ C Q
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGG- 2548
Query: 181 YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLC 236
Y CP+G ++ + A D NEC P C SC N G+RC+C G+ D A G C
Sbjct: 2549 YRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGC 2608
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
+D+DEC + C+ C NT G F C CP+G
Sbjct: 2609 QDVDECAGRRGPCS-YSCANTPGGFLCGCPQG 2639
Score = 187 bits (456), Expect = 6e-47
Identities = 155/470 (32%), Positives = 194/470 (41%), Gaps = 88/470 (18%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C NG C+N G + C C PG+ + +C+DVDEC +P C G CRN AGSYT
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYT 788
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRC-VNSEGS---FQCVCEAG--------- 108
C C PG +G +C D + + RC VN +G+ +C G
Sbjct: 789 CKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCER 848
Query: 109 --YRPTATRG-------ACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
P RG C DV+ECE VC NGRC NT GSFRCEC G L GR
Sbjct: 849 CEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRL 908
Query: 159 CLGLKLGWGVSCQACPAQGSE-LYAVLCPEGPSKDNGGADINECTAVP-GACPHGSCENL 216
C+ ++L + C + E V P D I V ACP E+L
Sbjct: 909 CVDVRL------EPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACP--DPESL 960
Query: 217 EPGYRCICDPGYHP----DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE 272
E C G+ +D++EC + C G CRNT GSF C C G +
Sbjct: 961 EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALD 1020
Query: 273 PELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECEC 332
+ + C DIDEC I P C G C+NT G FECEC
Sbjct: 1021 AQERNCTDIDECR----------------ISPDL---------CGQGTCVNTPGSFECEC 1055
Query: 333 ELGYVLD-ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
GY + C+D VD E A LL R C + GS
Sbjct: 1056 FPGYESGFMLMKNCMD----------VD---ECARDPLLCRGGTCTNTD---GSYKCQCP 1099
Query: 392 XXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
KG A C D+DEC+LS LC G CVN G+++C C G
Sbjct: 1100 PGHELTAKGTA------CEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAG 1143
Score = 176 bits (428), Expect = 2e-43
Identities = 115/324 (35%), Positives = 143/324 (44%), Gaps = 42/324 (12%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADV 80
+C G +EG RDVDECR +C G C N+ GS+ C C+ G+ P A A C D+
Sbjct: 2350 LCPHGSGYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC+ C N++GSF C C GY C D+DEC ++ C NT G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVG 2466
Query: 141 SFRCECLPGFTLSN----DGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG---PSKDN 193
+F C C PGFT + D C G GS + C +G S +
Sbjct: 2467 AFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGS--FRCECHQGFTLVSSGH 2524
Query: 194 GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSYCAGG 252
G D+NEC P C HG C+N GYRC C G+ + C D +EC + C
Sbjct: 2525 GCEDVNECDG-PHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSA 2582
Query: 253 QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTEL 312
CRNT G F CVCP G + L C+D+DEC G RG
Sbjct: 2583 SCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG-----------RRG------------ 2619
Query: 313 ASPCDNGRCINTHGGFECECELGY 336
PC C NT GGF C C GY
Sbjct: 2620 --PCSYS-CANTPGGFLCGCPQGY 2640
Score = 174 bits (424), Expect = 5e-43
Identities = 131/455 (28%), Positives = 188/455 (41%), Gaps = 75/455 (16%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
G++ + D+DEC++ P +C+ G C NT GS+ C C PG+ + C D+DEC+
Sbjct: 1551 GFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECS 1610
Query: 85 A-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC---RNGRCHNTPG 140
S+C G C N+ G++ CVC A Y C+D+ + VC NG C N
Sbjct: 1611 THSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM----RKSVCFRHYNGTCQNELA 1666
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLG--WGVSCQACPAQGSELYAVLC-PEGPS-----KD 192
F ++ C +G W C+ACP S Y +LC + P
Sbjct: 1667 ---------FNVTRK-MCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHT 1716
Query: 193 NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYC-A 250
DI+EC +P C +G C N +RC C G++ ++ L C D+DEC +S C
Sbjct: 1717 GKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ 1776
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
C N GS+ C C G + P C G E
Sbjct: 1777 NADCINIPGSYRCKCTRGYKLSPG-------GACVGRNECR------------------- 1810
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRR----GSCWRRVVDGQC 362
E+ + C +G C++T G + C C G+ A C+D +R+ G+C + C
Sbjct: 1811 EIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNC 1870
Query: 363 EAAAPELLLR--------QECCCSVG--LAWGSXXXXXXXXXXXXXKGF-AKLDGATCRD 411
P ++ EC VG +G GF DG C D
Sbjct: 1871 -LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD 1929
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+EC A C GTC N +GS+RC CPPG + S
Sbjct: 1930 TNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQS 1964
Score = 174 bits (424), Expect = 5e-43
Identities = 126/387 (32%), Positives = 161/387 (41%), Gaps = 66/387 (17%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-----------CR----DNPRVCR 50
+C NG C N G F C C G++ C D+ + CR + V R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 51 RGRCRNTAGSYTCLCE----PG------FAPTAAGYCA---DVDEC-AADSMCKGGRCVN 96
C + CE PG P +GY A DVDEC +C G C+N
Sbjct: 2322 AECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECIN 2381
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S GSF+C C+AGY P AT C+D+DEC + C NT GSF C C G+ L DG
Sbjct: 2382 SLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Query: 157 RTCLGLK--LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGAC-PHGS 212
RTC L +CQ + CP G ++ + D +EC+A PG C HG
Sbjct: 2442 RTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGH 2501
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
C N +RC C G+ + G C D++ECD C G C+N G + C CP+G
Sbjct: 2502 CHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQ 2559
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ C D +EC PPT C + C NT GGF C
Sbjct: 2560 HSQWAQCVDENECALS---------------PPT----------CGSASCRNTLGGFRCV 2594
Query: 332 CELGYVLDATAQRCLD-----NRRGSC 353
C G+ D C D RRG C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPC 2621
Score = 171 bits (416), Expect = 4e-42
Identities = 131/471 (27%), Positives = 182/471 (38%), Gaps = 63/471 (13%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C G C N G F+C C PGY +C D+DEC + +C G C NT G+YTC+
Sbjct: 1572 GLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCV 1631
Query: 65 CEPGFAPTAAG-YCADVDECAA----DSMCKGGRCVNSEGSFQCVCEAGYRPTATR--GA 117
C + G C D+ + + C+ N C C R A
Sbjct: 1632 CPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRK-MCCCSYNIGQAWNRPCEA 1690
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
C + Q +C N PG F + G L D + G+ G
Sbjct: 1691 CPTPISPDYQILCGN----QAPG-FLTDIHTGKPLDIDECGEIPAICANGICINQI---G 1742
Query: 178 SELYAVLCPEGPSKDN---GGADINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDAD 233
S + CP G + ++ D++EC + C + C N+ YRC C GY
Sbjct: 1743 S--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPG 1800
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE----GETE 289
G C +EC + C+ G C +T GS+ C+C G + + LC DIDEC+ G
Sbjct: 1801 GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT 1860
Query: 290 THYIESDY-----------ERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
I Y GD T + C G C+NT G F C C+ G+ L
Sbjct: 1861 CKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFEL 1920
Query: 339 DATAQRCLD-NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
A + C+D N S + G C+ C C G
Sbjct: 1921 TADGKNCVDTNECLSLAGTCLPGTCQNLEGSF----RCICPPGF---------------- 1960
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
++ C D+DEC+ LC GTC N+ GS++C CPPG L G
Sbjct: 1961 -----QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006
Score = 161 bits (392), Expect = 3e-39
Identities = 143/482 (29%), Positives = 185/482 (38%), Gaps = 85/482 (17%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G+CTNG+C N DG F C C GY G C D DEC C +G C N G +
Sbjct: 2091 NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNVIGGFE 2149
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF P C D+DEC+ + + RC N+EGS+ C C AGY C DVD
Sbjct: 2150 CACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVD 2209
Query: 123 ECEE-QRVC--RNGRCHNTPGSFRCECLPGF-TLSNDGRTCLGLKLGWGVSCQACPAQGS 178
EC + Q+ C R C N G+F C C PG L G C C AQ
Sbjct: 2210 ECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC--------TDDNECHAQPD 2261
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
LC G + G+ +C P C ++ G P + +CR
Sbjct: 2262 -----LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG------PCFAEVLQTMCR 2310
Query: 238 DI---DECDMHQSYCAGG------QCR----NTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
+ E C GG +C ++ +CP G+ + E RD+DEC
Sbjct: 2311 SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE---GRDVDEC 2367
Query: 285 --------EGE--TETHYIESDYERGDIPPTFPTR-------TELASPCDNGRCINTHGG 327
GE + G P T +++ PC C NT G
Sbjct: 2368 RMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGS 2426
Query: 328 FECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
F C C GY+L+ + C D C R C+ + C C
Sbjct: 2427 FLCSCPRGYLLEEDGRTCKD--LDECTSR--QHNCQFLCVNTVGAFTCRCP--------- 2473
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDS 446
GF + A C D DEC+ C A G C NT GS+RC+C G TL S
Sbjct: 2474 -----------PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 447 TG 448
+G
Sbjct: 2522 SG 2523
Score = 155 bits (375), Expect = 4e-37
Identities = 138/468 (29%), Positives = 183/468 (39%), Gaps = 91/468 (19%)
Query: 12 CKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
CKN+ G F C+C PG G C D +EC P +C GRC NTAGS+ C C+ GF
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 71 PTAA-GYCADVDE--CAADSMCKGGRCVNSEGSF----QCVCEAG--------------- 108
P+ C D+ + C A+ + R ++S +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 109 --YRPTATRGACV-----DVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
YR G+ DVDEC +C +G C N+ GSFRC C G+T TCL
Sbjct: 2345 SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCL 2404
Query: 161 GLKLGWGVS--CQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ V C + CP G + G D++ECT+ C C N
Sbjct: 2405 DMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVN 2463
Query: 216 LEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPE 274
+ C C PG+ C D DEC C A G C NT GSF C C +G
Sbjct: 2464 TVGAFTCRCPPGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSS 2522
Query: 275 LQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECEL 334
C D++EC+G P R C +G C N GG+ C C
Sbjct: 2523 GHGCEDVNECDG--------------------PHR------CQHG-CQNQLGGYRCSCPQ 2555
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXX 393
G+ + +C+D C + C +A+ L C C G +
Sbjct: 2556 GFTQHSQWAQCVDENE--C--ALSPPTCGSASCRNTLGGFRCVCPSGFDFDQA------- 2604
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
L G C+DVDECA C+ +C NT G + C CP G
Sbjct: 2605 ----------LGG--CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQG 2639
Score = 150 bits (363), Expect = 1e-35
Identities = 94/281 (33%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
MC NG+C N DG F C+CKPG+ G C D+DEC+ P +C G C NT GS+ C C
Sbjct: 540 MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQC 598
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD-E 123
G A G C D S C G +GS C + T T+ C + +
Sbjct: 599 LGGLAVGTDGRVCVDTH---VRSTCYG---AIEKGS----CARPFPGTVTKSECCCANPD 648
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
C+ N+ F+ C G ++ DGR L V Y
Sbjct: 649 HGFGEPCQLCPAKNS-AEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRC 707
Query: 184 LCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDI 239
+C G G D++EC C +G C+N Y C C PG+H D +C+D+
Sbjct: 708 VCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDV 767
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
DEC S C G CRN AGS+TC C G+R +P C D
Sbjct: 768 DEC--LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD 806
Score = 145 bits (351), Expect = 3e-34
Identities = 82/235 (34%), Positives = 111/235 (47%), Gaps = 14/235 (5%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+CKN G F C C GY +G C+D+DEC C+ C NT G++TC C PGF
Sbjct: 2419 LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFT 2477
Query: 71 PTAAGYCADVDECAADSMCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
C D DEC+A G G C N+ GSF+C C G+ ++ C DV+EC+
Sbjct: 2478 QHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPH 2536
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL----YAVL 184
C++G C N G +RC C GFT + C+ + +S C + + +
Sbjct: 2537 RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVD-ENECALSPPTCGSASCRNTLGGFRCV 2594
Query: 185 CPEGPSKDN--GGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
CP G D GG D++EC G C + SC N G+ C C GY G C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHC 2648
Score = 123 bits (296), Expect = 1e-27
Identities = 69/186 (37%), Positives = 88/186 (47%), Gaps = 7/186 (3%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C +G C N G F C C G+ S G C DV+EC D P C+ G C+N G Y C
Sbjct: 2494 GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHG-CQNQLGGYRC 2551
Query: 64 LCEPGFAPTAA-GYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C GF + C D +ECA + C C N+ G F+CVC +G+ G C DV
Sbjct: 2552 SCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
DEC +R + C NTPG F C C G+ + G G LG+ Q P + L
Sbjct: 2612 DECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSG--LGFSPGPQDTPDKEELLS 2669
Query: 182 AVLCPE 187
+ C E
Sbjct: 2670 SEACYE 2675
Score = 113 bits (273), Expect = 9e-25
Identities = 119/476 (25%), Positives = 167/476 (35%), Gaps = 73/476 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C+N+ G F CIC GYE G C D++EC D P C G C NT GSY C
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLC 1469
Query: 64 LCEPGFAPTAAGY-CADV--DECAADSMCKGGRCVNSEGSF-------QCVCEAGYRPTA 113
C F +G C D C ++ +G ++ C C G
Sbjct: 1470 SCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGN 1529
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSF--------RCECLPGFTLSNDGRTCLGLKLG 165
C + E + +C G P C+ LPG D G
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQ-PNRITVILEDIDECQELPGLCQGGDCVNTFG---- 1584
Query: 166 WGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICD 225
C+ P + +C DI+EC+ C G+C N Y C+C
Sbjct: 1585 -SFQCECPPGYHLSEHTRICE----------DIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 226 PGY-HPDADGLCRDIDECDMHQSYCAGGQCRNT-AGSFT---CVCPE--GTRHEPELQLC 278
Y + C D+ + + Y G C+N A + T C C G + C
Sbjct: 1634 AEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEAC 1691
Query: 279 R-----DIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECE 333
D G ++ +D G P E+ + C NG CIN G F CEC
Sbjct: 1692 PTPISPDYQILCGNQAPGFL-TDIHTGK-PLDIDECGEIPAICANGICINQIGSFRCECP 1749
Query: 334 LGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXX 393
G+ ++ C D C R Q A + C C+
Sbjct: 1750 AGFNYNSILLACEDV--DECGSRESPCQQNADCINIPGSYRCKCT--------------- 1792
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+G+ G C +EC +C+ G C++T+GSY C C G + T
Sbjct: 1793 -----RGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQT 1843
Score = 75.8 bits (178), Expect = 3e-13
Identities = 48/138 (34%), Positives = 63/138 (45%), Gaps = 9/138 (6%)
Query: 316 CDNG-RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NG RCI G C C G+ + +R D R G C+ +V C+ L+ +
Sbjct: 155 CHNGGRCI---GPNRCACVYGF-MGPQCER--DYRTGPCFGQVGPEGCQHQLTGLVCTKA 208
Query: 375 -CCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVNTDG 432
CC +VG AWG +GF + C+DVDEC LC GG+CVN G
Sbjct: 209 LCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVG 268
Query: 433 SYRCDCPPGLTLDSTGTA 450
S+ C CP G L + A
Sbjct: 269 SFHCRCPVGHRLSDSSAA 286
Score = 70.5 bits (165), Expect = 1e-11
Identities = 79/272 (29%), Positives = 97/272 (35%), Gaps = 45/272 (16%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT 72
N+ G F C PG+ + + C V CR R C G C C C G
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV-VPICR---RACGEGFCSQPN---LCTCADGTLAP 110
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
+ G C+ M GG C + C+C+ GY T D R C N
Sbjct: 111 SCGVSRG-SGCSVSCM-NGGTCRGAS----CLCQKGYTGTVCGQPICD-------RGCHN 157
Query: 133 G-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
G RC G RC C+ GF G C+ G + + PEG
Sbjct: 158 GGRCI---GPNRCACVYGFM---------------GPQCERDYRTGP-CFGQVGPEGCQH 198
Query: 192 DNGGADINE--CTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSY 248
G + C A G CE L P C G+ P+ G C+D+DEC
Sbjct: 199 QLTGLVCTKALCCATVGRAWGLPCE-LCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGL 257
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
C GG C N GSF C CP G R C D
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 61.7 bits (143), Expect = 5e-09
Identities = 23/70 (32%), Positives = 35/70 (50%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C+N G F C C +G+ L ++ C D R G+C+ + G+C R++C
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQC 317
Query: 376 CCSVGLAWGS 385
CC G W +
Sbjct: 318 CCDRGRCWAA 327
Score = 55.6 bits (128), Expect = 3e-07
Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C G+ P GAC DVDEC+ +C+ G C N GSF C C G LS+ C +
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Query: 164 LG 165
G
Sbjct: 292 AG 293
Score = 41.5 bits (93), Expect = 0.006
Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
C DVDEC S C G CVN G+Y C C PG T A
Sbjct: 447 CIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQA 486
Score = 40.3 bits (90), Expect = 0.014
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 5/68 (7%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCR-NTAGSYT- 62
G+C G C N+ G F C C G+ A C D V GRC + AG YT
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDY-RAGACFSVLFGGRCAGDLAGHYTR 314
Query: 63 --CLCEPG 68
C C+ G
Sbjct: 315 RQCCCDRG 322
>AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 308 bits (756), Expect = 3e-83
Identities = 170/465 (36%), Positives = 236/465 (50%), Gaps = 39/465 (8%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C +G C NI G + C C PG+++ C DVDEC + +C GRC NT GS+ C+C
Sbjct: 458 CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + G C D +ECA +MC G C+N +GSF C+C+ G+ C+D+DEC+
Sbjct: 518 AGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ 577
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG---WGV----SCQACPAQGS 178
+C NG C NT GSFRC+CL G + DGR C+ + +G SC A P G+
Sbjct: 578 TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC-ARPFPGT 636
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
+ C P D+G + C P S E ++ +C G DG RD
Sbjct: 637 VTKSECCCANP--DHGFGE--PCQLCPA---KNSAE-----FQALCSSGLGITTDG--RD 682
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIES 295
I+EC + CA G C N GS+ CVC G + C D+DEC + + + ++
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQN 742
Query: 296 D--YERGDIPPTFP--TRTE--------LASPCDNGRCINTHGGFECECELGYVLDATAQ 343
PP F TE L+SPC +G C N G + C+C G LD +
Sbjct: 743 SPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGT 802
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
CLD+ +G+CW ++ + +CE LR ECC ++G AWGS +GFA+
Sbjct: 803 FCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS-PCERCEIDPACARGFAR 861
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+ G TC DV+EC +C G CVNT GS+RC+CP GL LD++G
Sbjct: 862 MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 261 bits (639), Expect = 4e-69
Identities = 165/493 (33%), Positives = 221/493 (44%), Gaps = 55/493 (11%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+CT+G C+N G F C C G+ ++ C D+DECR +P +C +G C NT GS+ C
Sbjct: 995 GLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 65 CEPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG+ C DVDECA D +C GG C N++GS++C C G+ TA AC D+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHELTAKGTACEDI 1114
Query: 122 DECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQ 176
DEC +C +G+C N G+F+C C GF + D + C+ + G +
Sbjct: 1115 DECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE 1174
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
GS Y C +G S G AD++EC P C G C N+ G+RC+C G+ D
Sbjct: 1175 GS--YRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C D+DECD++ C G C NT GSF C C G C D+DEC E H
Sbjct: 1233 MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC--EVGGHN 1290
Query: 293 IESDYERGDIPPTFPTR---------------TELASP---CD-NGRCINTHGGFECECE 333
+S +IP +F R E S C G C+N G + C C
Sbjct: 1291 CDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 334 LGYVLDA----TAQRCLDN----RRGSCWRRVVDGQCEAAA---PELLLR-----QECCC 377
G+ D C +N G C +CE P R EC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ 1410
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYR 435
A+GS G+ +LD G C D++ECA C G C+NT GSY
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGY-ELDRGGGNCTDINECADPVN-CINGVCINTPGSYL 1468
Query: 436 CDCPPGLTLDSTG 448
C CP L+ +G
Sbjct: 1469 CSCPQDFELNPSG 1481
Score = 251 bits (614), Expect = 4e-66
Identities = 154/458 (33%), Positives = 196/458 (42%), Gaps = 60/458 (13%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RG-RCRNTAGSYTCLCEPGF 69
C N +G + C C GY +GA+CRDVDEC D + C RG C+N G++ C+C PG
Sbjct: 2181 CHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGM 2240
Query: 70 APTAAGY--CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
P C D +EC A +C GRCVN+ GSF+C C+ G++P+ T C D+
Sbjct: 2241 RPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDI----- 2295
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
R G C C L + + C G GWG C+ CP G+ Y LC
Sbjct: 2296 ----RQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLC 2351
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
P G G D++EC + C HG C N +RC C GY PDA C D+DEC
Sbjct: 2352 PHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQ 2411
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI-- 302
C C+NT GSF C CP G E + + C+D+DEC G
Sbjct: 2412 VPKPCT-FLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTC 2470
Query: 303 --PPTFPTRTELA----------SPCD-NGRCINTHGGFECECELGYVLDATAQRCLDNR 349
PP F + PC +G C NT G F CEC G+ L ++ C D
Sbjct: 2471 RCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED-- 2528
Query: 350 RGSCWRRVVDG--QCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA 407
C DG +C+ L C C G S A
Sbjct: 2529 VNEC-----DGPHRCQHGCQNQLGGYRCSCPQGFTQHS-------------------QWA 2564
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
C D +ECALS C +C NT G +RC CP G D
Sbjct: 2565 QCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFD 2602
Score = 236 bits (578), Expect = 1e-61
Identities = 158/481 (32%), Positives = 217/481 (45%), Gaps = 47/481 (9%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G C G C+N++G F CIC PG++ S+ C D+DEC + P +C G C N+ GS+ CL
Sbjct: 1938 GTCLPGTCQNLEGSFRCICPPGFQVQSDH--CIDIDECSEEPNLCLFGTCTNSPGSFQCL 1995
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCV--NSEGSFQCVCEAGYRPTATRGACVDV 121
C PGF + G+ C D + + + G+C + + + C RP G
Sbjct: 1996 CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWG----- 2050
Query: 122 DECEEQRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D CE +C F +PG S + G + GS
Sbjct: 2051 DPCE---LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGS- 2106
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ CP G S D G D +EC+ V C G+C N+ G+ C C G+ P C
Sbjct: 2107 -FRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCTNVIGGFECACADGFEPGLMMTC 2164
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETETHY--I 293
DIDEC ++ CA +C NT GS+ C CP G + +CRD+DEC +G+ + H +
Sbjct: 2165 EDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM 2223
Query: 294 ESDYERGDI----PP---TFPTRTE--------LASP--CDNGRCINTHGGFECECELGY 336
E G PP P E A P C NGRC+NT G F C+C+ G+
Sbjct: 2224 ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGF 2283
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEA--AAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
T C D R+G C+ V+ C + ++ E + R ECCC G WG
Sbjct: 2284 QPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPG 2343
Query: 395 XXXXKGFAKL-DGATC--RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
+ G T RDVDEC + A LCA G C+N+ GS+RC C G T D+T T
Sbjct: 2344 TSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Query: 452 L 452
L
Sbjct: 2404 L 2404
Score = 235 bits (574), Expect = 3e-61
Identities = 148/442 (33%), Positives = 197/442 (44%), Gaps = 46/442 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDEC 83
PG+ + D+DEC + P +C G C N GS+ C C GF + C DVDEC
Sbjct: 1708 PGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC 1767
Query: 84 AA-DSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPG 140
+ +S C + C+N GS++C C GY+ + GACV +EC E VC +G C +T G
Sbjct: 1768 GSRESPCQQNADCINIPGSYRCKCTRGYK-LSPGGACVGRNECREIPNVCSHGDCMDTEG 1826
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG-SELYAVLCPEGPSKDNGG--AD 197
S+ C C GF S D C+ + C + Y LC G + G D
Sbjct: 1827 SYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVD 1886
Query: 198 INECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCR 255
+ECT + G C G C N + C+C G+ ADG C D +EC C G C+
Sbjct: 1887 FDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N GSF C+CP G + + C DIDEC E
Sbjct: 1947 NLEGSFRCICPPG--FQVQSDHCIDIDECSEEPNL------------------------- 1979
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C N+ G F+C C G+VL RC D R+ C+ R G+C + C
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 376 CCS--VGLAWGSXXXXXXXXXXXXXK-----GFAKLDGA--TCRDVDECALSAELCAGGT 426
CCS G WG + G + G + DV+ECA + +C G
Sbjct: 2040 CCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGV 2099
Query: 427 CVNTDGSYRCDCPPGLTLDSTG 448
CVNTDGS+RC+CP G +LD TG
Sbjct: 2100 CVNTDGSFRCECPFGYSLDFTG 2121
Score = 224 bits (548), Expect = 4e-58
Identities = 154/461 (33%), Positives = 202/461 (43%), Gaps = 58/461 (12%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG+C+N+ G + C+C GYE+G+ G C DVDEC N +C G C+N+ GSY+C C
Sbjct: 692 VCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSC 751
Query: 66 EPGF-APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
PGF C DVDEC + S C G C N GS+ C C G R + C+D
Sbjct: 752 PPGFHFWQDTEICKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD---- 806
Query: 125 EEQRVCRNGRCHNTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
G C RCE L G +L ++ C L WG C+ C +
Sbjct: 807 -----STKGTCWLKIQESRCEVNLQGASLRSE--CCATLGAAWGSPCERCEIDPA----- 854
Query: 184 LCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDI- 239
C G ++ G D+NEC + PG CP+G C N +RC C G DA G LC D+
Sbjct: 855 -CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVR 913
Query: 240 -DECDMH--QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET----ETHY 292
+ C + + C G C C G E + C D + E + +
Sbjct: 914 LEPCFLRWDEDEC-GVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGF 972
Query: 293 IESDYERGDIPPTFPTRTE---LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
D+ G P + E C +G C NT G F C C G+ LDA + C D
Sbjct: 973 ASRDFLSG--RPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD-- 1028
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
+D +C +P+L C G + GF + C
Sbjct: 1029 --------ID-ECR-ISPDL-------CGQGTCVNTPGSFECECFPGYESGFMLM--KNC 1069
Query: 410 RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
DVDECA LC GGTC NTDGSY+C CPPG L + GTA
Sbjct: 1070 MDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHELTAKGTA 1110
Score = 224 bits (547), Expect = 6e-58
Identities = 150/457 (32%), Positives = 195/457 (42%), Gaps = 72/457 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C N G F C+C+ G+E ++G C D +EC C G C+N GS+ C
Sbjct: 1895 GQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRC 1954
Query: 64 LCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PGF + +C D+DEC+ + ++C G C NS GSFQC+C G+ + C D
Sbjct: 1955 ICPPGF-QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDT- 2012
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSEL 180
R C + +C F + R C + GWG C+ CP +GS
Sbjct: 2013 --------RQSFCFTRFEAGKCSVPKAFNTTKT-RCCCSKRPGEGWGDPCELCPQEGSAA 2063
Query: 181 YAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
+ LCP G P D+ D+NEC PG C +G C N + +RC C GY D G+
Sbjct: 2064 FQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGIN 2123
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL-CRDIDECEGETETHYIE 294
C D DEC + C G C N G F C C +G EP L + C DIDEC
Sbjct: 2124 CVDTDECSVGHP-CGQGTCTNVIGGFECACADG--FEPGLMMTCEDIDEC---------- 2170
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCW 354
+ P A C N T G + C C GY L C D C
Sbjct: 2171 ------SLNPLL-----CAFRCHN-----TEGSYLCTCPAGYTLREDGAMCRD--VDEC- 2211
Query: 355 RRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA--TCRDV 412
DGQ + A + EC +G G L G+ C D
Sbjct: 2212 ---ADGQQDCHARGM----ECKNLIG-----------TFACVCPPGMRPLPGSGEGCTDD 2253
Query: 413 DECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+EC +LC G CVNT GS+RCDC G T T
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLT 2290
Score = 213 bits (521), Expect = 8e-55
Identities = 142/421 (33%), Positives = 183/421 (43%), Gaps = 61/421 (14%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDEC-AADSMCKGGRC 94
+DV+EC+ P +C G CRNT GS+ C C GFA A C D+DEC + +C G C
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ GSF+C C GY C+DVDEC + +C G C NT GS++C+C PG L
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHEL 1104
Query: 153 SNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG-ADINECTAVPG 206
+ G C + L G+ + C G + D G DINEC G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 207 ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
C C N E YRC C GY DG C D+DEC+ + C G C N G C+C
Sbjct: 1165 GC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLC 1223
Query: 266 PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTH 325
+G P+++ C D+DEC D+ P C +G C NT
Sbjct: 1224 YDGFMATPDMRTCVDVDEC----------------DLNPHI---------CLHGDCENTK 1258
Query: 326 GGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
G F C C+LGY++ A C D C V C++ A L + C W
Sbjct: 1259 GSFVCHCQLGYMVRKGATGCSD--VDEC--EVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTL 444
DG C D+DEC C+ G C+N GSYRC C G
Sbjct: 1315 -------------------DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 445 D 445
D
Sbjct: 1356 D 1356
Score = 210 bits (513), Expect = 8e-54
Identities = 102/272 (37%), Positives = 143/272 (52%), Gaps = 12/272 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCL 64
+C NGIC N G F C C G+ S C DVDEC C++ C N GSY C
Sbjct: 1731 ICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 65 CEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G+ + G C +EC ++C G C+++EGS+ C+C G++ +A + C+D+DE
Sbjct: 1791 CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDE 1850
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP----AQGSE 179
C+ Q C NG C N GS+ C C PGF ++++G C+ + Q C +
Sbjct: 1851 CDRQ-PCGNGTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAG 1908
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ LC +G G D NEC ++ G C G+C+NLE +RCIC PG+ +D C
Sbjct: 1909 SFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDH-C 1967
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
DIDEC + C G C N+ GSF C+CP G
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPG 1999
Score = 206 bits (503), Expect = 1e-52
Identities = 161/471 (34%), Positives = 197/471 (41%), Gaps = 70/471 (14%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C G C N+ GGFEC C G+E G C D+DEC NP +C RC NT GSY C
Sbjct: 2133 GHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDIDECSLNPLLCAF-RCHNTEGSYLC 2190
Query: 64 LCEPGFAPTAAG-YCADVDECA---ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG-AC 118
C G+ G C DVDECA D +G C N G+F CVC G RP G C
Sbjct: 2191 TCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Query: 119 VDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
D +EC Q +C NGRC NT GSFRC+C GF S C ++ G C A
Sbjct: 2251 TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG---PCFA----- 2302
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLE-PG---YRCICDPGYHPDAD 233
E+ +C S + EC G CE PG YR +C G A+
Sbjct: 2303 -EVLQTMC-RSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE 2360
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G RD+DEC M CA G+C N+ GSF C C G + C D+DEC
Sbjct: 2361 G--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDEC--------- 2409
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD-----N 348
+++ PC C NT G F C C GY+L+ + C D +
Sbjct: 2410 ----------------SQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS 2452
Query: 349 RRGSCWRRVVD--GQCEAAAPELLLRQ--------ECCCSVGL--AWGSXXXXXXXXXXX 396
R+ +C V+ G P + EC G A G
Sbjct: 2453 RQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCE 2512
Query: 397 XXKGFAKLD-GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+GF + G C DV+EC C G C N G YRC CP G T S
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHS 2561
Score = 201 bits (490), Expect = 5e-51
Identities = 150/455 (32%), Positives = 193/455 (42%), Gaps = 42/455 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ GG C+C G+ + + C DVDEC NP +C G C NT GS+
Sbjct: 1203 NPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFV 1262
Query: 63 CLCEPGF-APTAAGYCADVDEC-AADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C+ G+ A C+DVDEC C C+N GSF C C G+ C
Sbjct: 1263 CHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECH 1320
Query: 120 DVDEC--EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC-----LGLKLGWGVSCQA 172
D+DEC +E R G C N PGS+RC C GF + DG C + + Q
Sbjct: 1321 DLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQC 1378
Query: 173 CPAQGSELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A G Y C G P++D+ D++EC A C GSCENL +RCIC+ GY
Sbjct: 1379 LNAPGG--YRCECEMGFDPTEDHRACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYE 1435
Query: 230 PD-ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET 288
D G C DI+EC C G C NT GS+ C CP+ P C D
Sbjct: 1436 LDRGGGNCTDINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFL 1494
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYVLDATAQRCL- 346
ETH +RGD E+ C + G + CEL + + T R L
Sbjct: 1495 ETH------DRGD--SGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLC 1546
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
G R+ ++ EC GL G L
Sbjct: 1547 PGGEGFQPNRIT-----VILEDI---DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 407 AT--CRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
T C D+DEC+ + +C GTC NT G+Y C CP
Sbjct: 1599 HTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 196 bits (477), Expect = 2e-49
Identities = 147/440 (33%), Positives = 184/440 (41%), Gaps = 47/440 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECA 84
PG + L + +D CR +C GRC T SY C C G+ G C DVDEC
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT 454
Query: 85 ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFR 143
+ S C G CVN G++ C C G++ T TR ACVDVDEC +C GRC NT GSF+
Sbjct: 455 S-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQ 513
Query: 144 CECLPGFTLSNDGRTCLG-LKLGWGVSC--QACPAQGSELYAVLCPEGPSKDNGG---AD 197
C C GF LS DG+ C+ + C C + ++ LC G GG D
Sbjct: 514 CVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGS-FSCLCKPGFLLAPGGHYCMD 572
Query: 198 INECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-R 255
I+EC PG C +G C N E +RC C G DG +C D G C R
Sbjct: 573 IDEC-QTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCAR 631
Query: 256 NTAGSFT---CVC--PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G+ T C C P+ EP QLC + E + G
Sbjct: 632 PFPGTVTKSECCCANPDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDP 690
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPEL 369
E+ C NG C N G + C C LGY A+ + C D + + D G C+ +
Sbjct: 691 EV---CANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGS- 746
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + D C+DVDEC S C G C N
Sbjct: 747 ---YSCSCPPGFHFWQ-------------------DTEICKDVDECLSSP--CVSGVCRN 782
Query: 430 TDGSYRCDCPPGLTLDSTGT 449
GSY C C PG LD +GT
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT 802
Score = 193 bits (471), Expect = 9e-49
Identities = 109/272 (40%), Positives = 138/272 (50%), Gaps = 14/272 (5%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G C N G F C C+ GY + C D+DEC P+ C C+NT GS+ C C
Sbjct: 2373 LCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSC 2431
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DEC + CVN+ G+F C C G+ T AC D DEC
Sbjct: 2432 PRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGF--TQHHQACFDNDEC 2489
Query: 125 EEQ-RVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQ-ACPAQGSEL 180
Q C +G CHNTPGSFRCEC GFTL + G C + G CQ C Q
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGG- 2548
Query: 181 YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLC 236
Y CP+G ++ + A D NEC P C SC N G+RC+C G+ D A G C
Sbjct: 2549 YRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGC 2608
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
+D+DEC + C+ C NT G F C CP+G
Sbjct: 2609 QDVDECAGRRGPCS-YSCANTPGGFLCGCPQG 2639
Score = 184 bits (448), Expect = 6e-46
Identities = 154/470 (32%), Positives = 193/470 (41%), Gaps = 88/470 (18%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C NG C+N G + C C PG+ + +C+DVDEC +P C G CRN AGSYT
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYT 788
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRC-VNSEGS---FQCVCEAG--------- 108
C C PG +G +C D + + RC VN +G+ +C G
Sbjct: 789 CKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCER 848
Query: 109 --YRPTATRG-------ACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
P RG C DV+ECE VC NGRC NT GSFRCEC G L GR
Sbjct: 849 CEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRL 908
Query: 159 CLGLKLGWGVSCQACPAQGSE-LYAVLCPEGPSKDNGGADINECTAVP-GACPHGSCENL 216
C+ ++L + C + E V P D I V ACP E+L
Sbjct: 909 CVDVRL------EPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACP--DPESL 960
Query: 217 EPGYRCICDPGYHP----DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE 272
E C G+ +D++EC + C G CRNT GSF C C G +
Sbjct: 961 EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALD 1020
Query: 273 PELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECEC 332
+ + C DIDEC I P C G C+NT G FECEC
Sbjct: 1021 AQERNCTDIDECR----------------ISPDL---------CGQGTCVNTPGSFECEC 1055
Query: 333 ELGYVLD-ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
GY + C+D VD E A LL C + GS
Sbjct: 1056 FPGYESGFMLMKNCMD----------VD---ECARDPLLCWGGTCTNTD---GSYKCQCP 1099
Query: 392 XXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
KG A C D+DEC+LS LC G CVN G+++C C G
Sbjct: 1100 PGHELTAKGTA------CEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAG 1143
Score = 176 bits (428), Expect = 2e-43
Identities = 115/324 (35%), Positives = 143/324 (44%), Gaps = 42/324 (12%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADV 80
+C G +EG RDVDECR +C G C N+ GS+ C C+ G+ P A A C D+
Sbjct: 2350 LCPHGSGYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC+ C N++GSF C C GY C D+DEC ++ C NT G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVG 2466
Query: 141 SFRCECLPGFTLSN----DGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG---PSKDN 193
+F C C PGFT + D C G GS + C +G S +
Sbjct: 2467 AFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGS--FRCECHQGFTLVSSGH 2524
Query: 194 GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSYCAGG 252
G D+NEC P C HG C+N GYRC C G+ + C D +EC + C
Sbjct: 2525 GCEDVNECDG-PHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSA 2582
Query: 253 QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTEL 312
CRNT G F CVCP G + L C+D+DEC G RG
Sbjct: 2583 SCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG-----------RRG------------ 2619
Query: 313 ASPCDNGRCINTHGGFECECELGY 336
PC C NT GGF C C GY
Sbjct: 2620 --PCSYS-CANTPGGFLCGCPQGY 2640
Score = 174 bits (424), Expect = 5e-43
Identities = 131/455 (28%), Positives = 188/455 (41%), Gaps = 75/455 (16%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
G++ + D+DEC++ P +C+ G C NT GS+ C C PG+ + C D+DEC+
Sbjct: 1551 GFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECS 1610
Query: 85 A-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC---RNGRCHNTPG 140
S+C G C N+ G++ CVC A Y C+D+ + VC NG C N
Sbjct: 1611 THSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM----RKSVCFRHYNGTCQNELA 1666
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLG--WGVSCQACPAQGSELYAVLC-PEGPS-----KD 192
F ++ C +G W C+ACP S Y +LC + P
Sbjct: 1667 ---------FNVTRK-MCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHT 1716
Query: 193 NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYC-A 250
DI+EC +P C +G C N +RC C G++ ++ L C D+DEC +S C
Sbjct: 1717 GKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ 1776
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
C N GS+ C C G + P C G E
Sbjct: 1777 NADCINIPGSYRCKCTRGYKLSPG-------GACVGRNECR------------------- 1810
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRR----GSCWRRVVDGQC 362
E+ + C +G C++T G + C C G+ A C+D +R+ G+C + C
Sbjct: 1811 EIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNC 1870
Query: 363 EAAAPELLLR--------QECCCSVG--LAWGSXXXXXXXXXXXXXKGF-AKLDGATCRD 411
P ++ EC VG +G GF DG C D
Sbjct: 1871 -LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD 1929
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+EC A C GTC N +GS+RC CPPG + S
Sbjct: 1930 TNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQS 1964
Score = 174 bits (424), Expect = 5e-43
Identities = 126/387 (32%), Positives = 161/387 (41%), Gaps = 66/387 (17%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-----------CR----DNPRVCR 50
+C NG C N G F C C G++ C D+ + CR + V R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 51 RGRCRNTAGSYTCLCE----PG------FAPTAAGYCA---DVDEC-AADSMCKGGRCVN 96
C + CE PG P +GY A DVDEC +C G C+N
Sbjct: 2322 AECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECIN 2381
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S GSF+C C+AGY P AT C+D+DEC + C NT GSF C C G+ L DG
Sbjct: 2382 SLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Query: 157 RTCLGLK--LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGAC-PHGS 212
RTC L +CQ + CP G ++ + D +EC+A PG C HG
Sbjct: 2442 RTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGH 2501
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
C N +RC C G+ + G C D++ECD C G C+N G + C CP+G
Sbjct: 2502 CHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQ 2559
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ C D +EC PPT C + C NT GGF C
Sbjct: 2560 HSQWAQCVDENECALS---------------PPT----------CGSASCRNTLGGFRCV 2594
Query: 332 CELGYVLDATAQRCLD-----NRRGSC 353
C G+ D C D RRG C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPC 2621
Score = 171 bits (416), Expect = 4e-42
Identities = 131/471 (27%), Positives = 182/471 (38%), Gaps = 63/471 (13%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C G C N G F+C C PGY +C D+DEC + +C G C NT G+YTC+
Sbjct: 1572 GLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCV 1631
Query: 65 CEPGFAPTAAG-YCADVDECAA----DSMCKGGRCVNSEGSFQCVCEAGYRPTATR--GA 117
C + G C D+ + + C+ N C C R A
Sbjct: 1632 CPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRK-MCCCSYNIGQAWNRPCEA 1690
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
C + Q +C N PG F + G L D + G+ G
Sbjct: 1691 CPTPISPDYQILCGN----QAPG-FLTDIHTGKPLDIDECGEIPAICANGICINQI---G 1742
Query: 178 SELYAVLCPEGPSKDN---GGADINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDAD 233
S + CP G + ++ D++EC + C + C N+ YRC C GY
Sbjct: 1743 S--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPG 1800
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE----GETE 289
G C +EC + C+ G C +T GS+ C+C G + + LC DIDEC+ G
Sbjct: 1801 GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT 1860
Query: 290 THYIESDY-----------ERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
I Y GD T + C G C+NT G F C C+ G+ L
Sbjct: 1861 CKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFEL 1920
Query: 339 DATAQRCLD-NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
A + C+D N S + G C+ C C G
Sbjct: 1921 TADGKNCVDTNECLSLAGTCLPGTCQNLEGSF----RCICPPGF---------------- 1960
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
++ C D+DEC+ LC GTC N+ GS++C CPPG L G
Sbjct: 1961 -----QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006
Score = 161 bits (392), Expect = 3e-39
Identities = 143/482 (29%), Positives = 185/482 (38%), Gaps = 85/482 (17%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G+CTNG+C N DG F C C GY G C D DEC C +G C N G +
Sbjct: 2091 NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNVIGGFE 2149
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF P C D+DEC+ + + RC N+EGS+ C C AGY C DVD
Sbjct: 2150 CACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVD 2209
Query: 123 ECEE-QRVC--RNGRCHNTPGSFRCECLPGF-TLSNDGRTCLGLKLGWGVSCQACPAQGS 178
EC + Q+ C R C N G+F C C PG L G C C AQ
Sbjct: 2210 ECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC--------TDDNECHAQPD 2261
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
LC G + G+ +C P C ++ G P + +CR
Sbjct: 2262 -----LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG------PCFAEVLQTMCR 2310
Query: 238 DI---DECDMHQSYCAGG------QCR----NTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
+ E C GG +C ++ +CP G+ + E RD+DEC
Sbjct: 2311 SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE---GRDVDEC 2367
Query: 285 --------EGE--TETHYIESDYERGDIPPTFPTR-------TELASPCDNGRCINTHGG 327
GE + G P T +++ PC C NT G
Sbjct: 2368 RMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGS 2426
Query: 328 FECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
F C C GY+L+ + C D C R C+ + C C
Sbjct: 2427 FLCSCPRGYLLEEDGRTCKD--LDECTSR--QHNCQFLCVNTVGAFTCRCP--------- 2473
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDS 446
GF + A C D DEC+ C A G C NT GS+RC+C G TL S
Sbjct: 2474 -----------PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 447 TG 448
+G
Sbjct: 2522 SG 2523
Score = 155 bits (375), Expect = 4e-37
Identities = 138/468 (29%), Positives = 183/468 (39%), Gaps = 91/468 (19%)
Query: 12 CKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
CKN+ G F C+C PG G C D +EC P +C GRC NTAGS+ C C+ GF
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 71 PTAA-GYCADVDE--CAADSMCKGGRCVNSEGSF----QCVCEAG--------------- 108
P+ C D+ + C A+ + R ++S +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 109 --YRPTATRGACV-----DVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
YR G+ DVDEC +C +G C N+ GSFRC C G+T TCL
Sbjct: 2345 SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCL 2404
Query: 161 GLKLGWGVS--CQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ V C + CP G + G D++ECT+ C C N
Sbjct: 2405 DMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVN 2463
Query: 216 LEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPE 274
+ C C PG+ C D DEC C A G C NT GSF C C +G
Sbjct: 2464 TVGAFTCRCPPGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSS 2522
Query: 275 LQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECEL 334
C D++EC+G P R C +G C N GG+ C C
Sbjct: 2523 GHGCEDVNECDG--------------------PHR------CQHG-CQNQLGGYRCSCPQ 2555
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXX 393
G+ + +C+D C + C +A+ L C C G +
Sbjct: 2556 GFTQHSQWAQCVDENE--C--ALSPPTCGSASCRNTLGGFRCVCPSGFDFDQA------- 2604
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
L G C+DVDECA C+ +C NT G + C CP G
Sbjct: 2605 ----------LGG--CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQG 2639
Score = 150 bits (363), Expect = 1e-35
Identities = 94/281 (33%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
MC NG+C N DG F C+CKPG+ G C D+DEC+ P +C G C NT GS+ C C
Sbjct: 540 MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQC 598
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD-E 123
G A G C D S C G +GS C + T T+ C + +
Sbjct: 599 LGGLAVGTDGRVCVDTH---VRSTCYG---AIEKGS----CARPFPGTVTKSECCCANPD 648
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
C+ N+ F+ C G ++ DGR L V Y
Sbjct: 649 HGFGEPCQLCPAKNS-AEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRC 707
Query: 184 LCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDI 239
+C G G D++EC C +G C+N Y C C PG+H D +C+D+
Sbjct: 708 VCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDV 767
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
DEC S C G CRN AGS+TC C G+R +P C D
Sbjct: 768 DEC--LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD 806
Score = 145 bits (351), Expect = 3e-34
Identities = 82/235 (34%), Positives = 111/235 (47%), Gaps = 14/235 (5%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+CKN G F C C GY +G C+D+DEC C+ C NT G++TC C PGF
Sbjct: 2419 LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFT 2477
Query: 71 PTAAGYCADVDECAADSMCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
C D DEC+A G G C N+ GSF+C C G+ ++ C DV+EC+
Sbjct: 2478 QHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPH 2536
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL----YAVL 184
C++G C N G +RC C GFT + C+ + +S C + + +
Sbjct: 2537 RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVD-ENECALSPPTCGSASCRNTLGGFRCV 2594
Query: 185 CPEGPSKDN--GGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
CP G D GG D++EC G C + SC N G+ C C GY G C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHC 2648
Score = 123 bits (296), Expect = 1e-27
Identities = 69/186 (37%), Positives = 88/186 (47%), Gaps = 7/186 (3%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C +G C N G F C C G+ S G C DV+EC D P C+ G C+N G Y C
Sbjct: 2494 GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHG-CQNQLGGYRC 2551
Query: 64 LCEPGFAPTAA-GYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C GF + C D +ECA + C C N+ G F+CVC +G+ G C DV
Sbjct: 2552 SCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
DEC +R + C NTPG F C C G+ + G G LG+ Q P + L
Sbjct: 2612 DECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSG--LGFSPGPQDTPDKEELLS 2669
Query: 182 AVLCPE 187
+ C E
Sbjct: 2670 SEACYE 2675
Score = 113 bits (273), Expect = 9e-25
Identities = 119/476 (25%), Positives = 167/476 (35%), Gaps = 73/476 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C+N+ G F CIC GYE G C D++EC D P C G C NT GSY C
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLC 1469
Query: 64 LCEPGFAPTAAGY-CADV--DECAADSMCKGGRCVNSEGSF-------QCVCEAGYRPTA 113
C F +G C D C ++ +G ++ C C G
Sbjct: 1470 SCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGN 1529
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSF--------RCECLPGFTLSNDGRTCLGLKLG 165
C + E + +C G P C+ LPG D G
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQ-PNRITVILEDIDECQELPGLCQGGDCVNTFG---- 1584
Query: 166 WGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICD 225
C+ P + +C DI+EC+ C G+C N Y C+C
Sbjct: 1585 -SFQCECPPGYHLSEHTRICE----------DIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 226 PGY-HPDADGLCRDIDECDMHQSYCAGGQCRNT-AGSFT---CVCPE--GTRHEPELQLC 278
Y + C D+ + + Y G C+N A + T C C G + C
Sbjct: 1634 AEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEAC 1691
Query: 279 R-----DIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECE 333
D G ++ +D G P E+ + C NG CIN G F CEC
Sbjct: 1692 PTPISPDYQILCGNQAPGFL-TDIHTGK-PLDIDECGEIPAICANGICINQIGSFRCECP 1749
Query: 334 LGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXX 393
G+ ++ C D C R Q A + C C+
Sbjct: 1750 AGFNYNSILLACEDV--DECGSRESPCQQNADCINIPGSYRCKCT--------------- 1792
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+G+ G C +EC +C+ G C++T+GSY C C G + T
Sbjct: 1793 -----RGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQT 1843
Score = 75.8 bits (178), Expect = 3e-13
Identities = 48/138 (34%), Positives = 63/138 (45%), Gaps = 9/138 (6%)
Query: 316 CDNG-RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NG RCI G C C G+ + +R D R G C+ +V C+ L+ +
Sbjct: 155 CHNGGRCI---GPNRCACVYGF-MGPQCER--DYRTGPCFGQVGPEGCQHQLTGLVCTKA 208
Query: 375 -CCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVNTDG 432
CC +VG AWG +GF + C+DVDEC LC GG+CVN G
Sbjct: 209 LCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVG 268
Query: 433 SYRCDCPPGLTLDSTGTA 450
S+ C CP G L + A
Sbjct: 269 SFHCRCPVGHRLSDSSAA 286
Score = 70.5 bits (165), Expect = 1e-11
Identities = 79/272 (29%), Positives = 97/272 (35%), Gaps = 45/272 (16%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT 72
N+ G F C PG+ + + C V CR R C G C C C G
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV-VPICR---RACGEGFCSQPN---LCTCADGTLAP 110
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
+ G C+ M GG C + C+C+ GY T D R C N
Sbjct: 111 SCGVSRG-SGCSVSCM-NGGTCRGAS----CLCQKGYTGTVCGQPICD-------RGCHN 157
Query: 133 G-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
G RC G RC C+ GF G C+ G + + PEG
Sbjct: 158 GGRCI---GPNRCACVYGFM---------------GPQCERDYRTGP-CFGQVGPEGCQH 198
Query: 192 DNGGADINE--CTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSY 248
G + C A G CE L P C G+ P+ G C+D+DEC
Sbjct: 199 QLTGLVCTKALCCATVGRAWGLPCE-LCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGL 257
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
C GG C N GSF C CP G R C D
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 61.7 bits (143), Expect = 5e-09
Identities = 23/70 (32%), Positives = 35/70 (50%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C+N G F C C +G+ L ++ C D R G+C+ + G+C R++C
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQC 317
Query: 376 CCSVGLAWGS 385
CC G W +
Sbjct: 318 CCDRGRCWAA 327
Score = 55.6 bits (128), Expect = 3e-07
Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C G+ P GAC DVDEC+ +C+ G C N GSF C C G LS+ C +
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Query: 164 LG 165
G
Sbjct: 292 AG 293
Score = 41.5 bits (93), Expect = 0.006
Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
C DVDEC S C G CVN G+Y C C PG T A
Sbjct: 447 CIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQA 486
Score = 40.3 bits (90), Expect = 0.014
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 5/68 (7%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCR-NTAGSYT- 62
G+C G C N+ G F C C G+ A C D V GRC + AG YT
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDY-RAGACFSVLFGGRCAGDLAGHYTR 314
Query: 63 --CLCEPG 68
C C+ G
Sbjct: 315 RQCCCDRG 322
>AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 308 bits (756), Expect = 3e-83
Identities = 170/465 (36%), Positives = 236/465 (50%), Gaps = 39/465 (8%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C +G C NI G + C C PG+++ C DVDEC + +C GRC NT GS+ C+C
Sbjct: 458 CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + G C D +ECA +MC G C+N +GSF C+C+ G+ C+D+DEC+
Sbjct: 518 AGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ 577
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG---WGV----SCQACPAQGS 178
+C NG C NT GSFRC+CL G + DGR C+ + +G SC A P G+
Sbjct: 578 TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC-ARPFPGT 636
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
+ C P D+G + C P S E ++ +C G DG RD
Sbjct: 637 VTKSECCCANP--DHGFGE--PCQLCPA---KNSAE-----FQALCSSGLGITTDG--RD 682
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIES 295
I+EC + CA G C N GS+ CVC G + C D+DEC + + + ++
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQN 742
Query: 296 D--YERGDIPPTFP--TRTE--------LASPCDNGRCINTHGGFECECELGYVLDATAQ 343
PP F TE L+SPC +G C N G + C+C G LD +
Sbjct: 743 SPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGT 802
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
CLD+ +G+CW ++ + +CE LR ECC ++G AWGS +GFA+
Sbjct: 803 FCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS-PCERCEIDPACARGFAR 861
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+ G TC DV+EC +C G CVNT GS+RC+CP GL LD++G
Sbjct: 862 MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 263 bits (644), Expect = 1e-69
Identities = 165/493 (33%), Positives = 222/493 (45%), Gaps = 55/493 (11%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+CT+G C+N G F C C G+ ++ C D+DECR +P +C +G C NT GS+ C
Sbjct: 995 GLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 65 CEPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG+ C DVDECA D +C+GG C N++GS++C C G+ TA AC D+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDI 1114
Query: 122 DECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQ 176
DEC +C +G+C N G+F+C C GF + D + C+ + G +
Sbjct: 1115 DECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE 1174
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
GS Y C +G S G AD++EC P C G C N+ G+RC+C G+ D
Sbjct: 1175 GS--YRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C D+DECD++ C G C NT GSF C C G C D+DEC E H
Sbjct: 1233 MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC--EVGGHN 1290
Query: 293 IESDYERGDIPPTFPTR---------------TELASP---CD-NGRCINTHGGFECECE 333
+S +IP +F R E S C G C+N G + C C
Sbjct: 1291 CDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 334 LGYVLDA----TAQRCLDN----RRGSCWRRVVDGQCEAAA---PELLLR-----QECCC 377
G+ D C +N G C +CE P R EC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ 1410
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYR 435
A+GS G+ +LD G C D++ECA C G C+NT GSY
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGY-ELDRGGGNCTDINECADPVN-CINGVCINTPGSYL 1468
Query: 436 CDCPPGLTLDSTG 448
C CP L+ +G
Sbjct: 1469 CSCPQDFELNPSG 1481
Score = 251 bits (614), Expect = 4e-66
Identities = 154/458 (33%), Positives = 196/458 (42%), Gaps = 60/458 (13%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RG-RCRNTAGSYTCLCEPGF 69
C N +G + C C GY +GA+CRDVDEC D + C RG C+N G++ C+C PG
Sbjct: 2181 CHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGM 2240
Query: 70 APTAAGY--CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
P C D +EC A +C GRCVN+ GSF+C C+ G++P+ T C D+
Sbjct: 2241 RPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDI----- 2295
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
R G C C L + + C G GWG C+ CP G+ Y LC
Sbjct: 2296 ----RQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLC 2351
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
P G G D++EC + C HG C N +RC C GY PDA C D+DEC
Sbjct: 2352 PHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQ 2411
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI-- 302
C C+NT GSF C CP G E + + C+D+DEC G
Sbjct: 2412 VPKPCT-FLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTC 2470
Query: 303 --PPTFPTRTELA----------SPCD-NGRCINTHGGFECECELGYVLDATAQRCLDNR 349
PP F + PC +G C NT G F CEC G+ L ++ C D
Sbjct: 2471 RCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED-- 2528
Query: 350 RGSCWRRVVDG--QCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA 407
C DG +C+ L C C G S A
Sbjct: 2529 VNEC-----DGPHRCQHGCQNQLGGYRCSCPQGFTQHS-------------------QWA 2564
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
C D +ECALS C +C NT G +RC CP G D
Sbjct: 2565 QCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFD 2602
Score = 236 bits (578), Expect = 1e-61
Identities = 158/481 (32%), Positives = 217/481 (45%), Gaps = 47/481 (9%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G C G C+N++G F CIC PG++ S+ C D+DEC + P +C G C N+ GS+ CL
Sbjct: 1938 GTCLPGTCQNLEGSFRCICPPGFQVQSDH--CIDIDECSEEPNLCLFGTCTNSPGSFQCL 1995
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCV--NSEGSFQCVCEAGYRPTATRGACVDV 121
C PGF + G+ C D + + + G+C + + + C RP G
Sbjct: 1996 CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWG----- 2050
Query: 122 DECEEQRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D CE +C F +PG S + G + GS
Sbjct: 2051 DPCE---LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGS- 2106
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ CP G S D G D +EC+ V C G+C N+ G+ C C G+ P C
Sbjct: 2107 -FRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCTNVIGGFECACADGFEPGLMMTC 2164
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETETHY--I 293
DIDEC ++ CA +C NT GS+ C CP G + +CRD+DEC +G+ + H +
Sbjct: 2165 EDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM 2223
Query: 294 ESDYERGDI----PP---TFPTRTE--------LASP--CDNGRCINTHGGFECECELGY 336
E G PP P E A P C NGRC+NT G F C+C+ G+
Sbjct: 2224 ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGF 2283
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEA--AAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
T C D R+G C+ V+ C + ++ E + R ECCC G WG
Sbjct: 2284 QPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPG 2343
Query: 395 XXXXKGFAKL-DGATC--RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
+ G T RDVDEC + A LCA G C+N+ GS+RC C G T D+T T
Sbjct: 2344 TSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Query: 452 L 452
L
Sbjct: 2404 L 2404
Score = 235 bits (574), Expect = 3e-61
Identities = 148/442 (33%), Positives = 197/442 (44%), Gaps = 46/442 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDEC 83
PG+ + D+DEC + P +C G C N GS+ C C GF + C DVDEC
Sbjct: 1708 PGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC 1767
Query: 84 AA-DSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPG 140
+ +S C + C+N GS++C C GY+ + GACV +EC E VC +G C +T G
Sbjct: 1768 GSRESPCQQNADCINIPGSYRCKCTRGYK-LSPGGACVGRNECREIPNVCSHGDCMDTEG 1826
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG-SELYAVLCPEGPSKDNGG--AD 197
S+ C C GF S D C+ + C + Y LC G + G D
Sbjct: 1827 SYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVD 1886
Query: 198 INECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCR 255
+ECT + G C G C N + C+C G+ ADG C D +EC C G C+
Sbjct: 1887 FDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N GSF C+CP G + + C DIDEC E
Sbjct: 1947 NLEGSFRCICPPG--FQVQSDHCIDIDECSEEPNL------------------------- 1979
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C N+ G F+C C G+VL RC D R+ C+ R G+C + C
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 376 CCS--VGLAWGSXXXXXXXXXXXXXK-----GFAKLDGA--TCRDVDECALSAELCAGGT 426
CCS G WG + G + G + DV+ECA + +C G
Sbjct: 2040 CCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGV 2099
Query: 427 CVNTDGSYRCDCPPGLTLDSTG 448
CVNTDGS+RC+CP G +LD TG
Sbjct: 2100 CVNTDGSFRCECPFGYSLDFTG 2121
Score = 224 bits (548), Expect = 4e-58
Identities = 154/461 (33%), Positives = 202/461 (43%), Gaps = 58/461 (12%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG+C+N+ G + C+C GYE+G+ G C DVDEC N +C G C+N+ GSY+C C
Sbjct: 692 VCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSC 751
Query: 66 EPGF-APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
PGF C DVDEC + S C G C N GS+ C C G R + C+D
Sbjct: 752 PPGFHFWQDTEICKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD---- 806
Query: 125 EEQRVCRNGRCHNTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
G C RCE L G +L ++ C L WG C+ C +
Sbjct: 807 -----STKGTCWLKIQESRCEVNLQGASLRSE--CCATLGAAWGSPCERCEIDPA----- 854
Query: 184 LCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDI- 239
C G ++ G D+NEC + PG CP+G C N +RC C G DA G LC D+
Sbjct: 855 -CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVR 913
Query: 240 -DECDMH--QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET----ETHY 292
+ C + + C G C C G E + C D + E + +
Sbjct: 914 LEPCFLRWDEDEC-GVTLPGKYRMDFCCCSIGAVWGVECEACPDPESLEFASLCPRGLGF 972
Query: 293 IESDYERGDIPPTFPTRTE---LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
D+ G P + E C +G C NT G F C C G+ LDA + C D
Sbjct: 973 ASRDFLSG--RPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD-- 1028
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
+D +C +P+L C G + GF + C
Sbjct: 1029 --------ID-ECR-ISPDL-------CGQGTCVNTPGSFECECFPGYESGFMLM--KNC 1069
Query: 410 RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
DVDECA LC GGTC NTDGSY+C CPPG L + GTA
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTA 1110
Score = 224 bits (547), Expect = 6e-58
Identities = 150/457 (32%), Positives = 195/457 (42%), Gaps = 72/457 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C N G F C+C+ G+E ++G C D +EC C G C+N GS+ C
Sbjct: 1895 GQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRC 1954
Query: 64 LCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PGF + +C D+DEC+ + ++C G C NS GSFQC+C G+ + C D
Sbjct: 1955 ICPPGF-QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDT- 2012
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSEL 180
R C + +C F + R C + GWG C+ CP +GS
Sbjct: 2013 --------RQSFCFTRFEAGKCSVPKAFNTTKT-RCCCSKRPGEGWGDPCELCPQEGSAA 2063
Query: 181 YAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
+ LCP G P D+ D+NEC PG C +G C N + +RC C GY D G+
Sbjct: 2064 FQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGIN 2123
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL-CRDIDECEGETETHYIE 294
C D DEC + C G C N G F C C +G EP L + C DIDEC
Sbjct: 2124 CVDTDECSVGHP-CGQGTCTNVIGGFECACADG--FEPGLMMTCEDIDEC---------- 2170
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCW 354
+ P A C N T G + C C GY L C D C
Sbjct: 2171 ------SLNPLL-----CAFRCHN-----TEGSYLCTCPAGYTLREDGAMCRD--VDEC- 2211
Query: 355 RRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA--TCRDV 412
DGQ + A + EC +G G L G+ C D
Sbjct: 2212 ---ADGQQDCHARGM----ECKNLIG-----------TFACVCPPGMRPLPGSGEGCTDD 2253
Query: 413 DECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+EC +LC G CVNT GS+RCDC G T T
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLT 2290
Score = 217 bits (529), Expect = 9e-56
Identities = 143/421 (33%), Positives = 184/421 (43%), Gaps = 61/421 (14%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDEC-AADSMCKGGRC 94
+DV+EC+ P +C G CRNT GS+ C C GFA A C D+DEC + +C G C
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ GSF+C C GY C+DVDEC + +CR G C NT GS++C+C PG L
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 153 SNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG-ADINECTAVPG 206
+ G C + L G+ + C G + D G DINEC G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 207 ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
C C N E YRC C GY DG C D+DEC+ + C G C N G C+C
Sbjct: 1165 GC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLC 1223
Query: 266 PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTH 325
+G P+++ C D+DEC D+ P C +G C NT
Sbjct: 1224 YDGFMATPDMRTCVDVDEC----------------DLNPHI---------CLHGDCENTK 1258
Query: 326 GGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
G F C C+LGY++ A C D C V C++ A L + C W
Sbjct: 1259 GSFVCHCQLGYMVRKGATGCSD--VDEC--EVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTL 444
DG C D+DEC C+ G C+N GSYRC C G
Sbjct: 1315 -------------------DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 445 D 445
D
Sbjct: 1356 D 1356
Score = 210 bits (513), Expect = 8e-54
Identities = 102/272 (37%), Positives = 143/272 (52%), Gaps = 12/272 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCL 64
+C NGIC N G F C C G+ S C DVDEC C++ C N GSY C
Sbjct: 1731 ICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 65 CEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G+ + G C +EC ++C G C+++EGS+ C+C G++ +A + C+D+DE
Sbjct: 1791 CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDE 1850
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP----AQGSE 179
C+ Q C NG C N GS+ C C PGF ++++G C+ + Q C +
Sbjct: 1851 CDRQ-PCGNGTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAG 1908
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ LC +G G D NEC ++ G C G+C+NLE +RCIC PG+ +D C
Sbjct: 1909 SFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDH-C 1967
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
DIDEC + C G C N+ GSF C+CP G
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPG 1999
Score = 206 bits (503), Expect = 1e-52
Identities = 161/471 (34%), Positives = 197/471 (41%), Gaps = 70/471 (14%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C G C N+ GGFEC C G+E G C D+DEC NP +C RC NT GSY C
Sbjct: 2133 GHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDIDECSLNPLLCAF-RCHNTEGSYLC 2190
Query: 64 LCEPGFAPTAAG-YCADVDECA---ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG-AC 118
C G+ G C DVDECA D +G C N G+F CVC G RP G C
Sbjct: 2191 TCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Query: 119 VDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
D +EC Q +C NGRC NT GSFRC+C GF S C ++ G C A
Sbjct: 2251 TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG---PCFA----- 2302
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLE-PG---YRCICDPGYHPDAD 233
E+ +C S + EC G CE PG YR +C G A+
Sbjct: 2303 -EVLQTMC-RSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE 2360
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G RD+DEC M CA G+C N+ GSF C C G + C D+DEC
Sbjct: 2361 G--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDEC--------- 2409
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD-----N 348
+++ PC C NT G F C C GY+L+ + C D +
Sbjct: 2410 ----------------SQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS 2452
Query: 349 RRGSCWRRVVD--GQCEAAAPELLLRQ--------ECCCSVGL--AWGSXXXXXXXXXXX 396
R+ +C V+ G P + EC G A G
Sbjct: 2453 RQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCE 2512
Query: 397 XXKGFAKLD-GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+GF + G C DV+EC C G C N G YRC CP G T S
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHS 2561
Score = 201 bits (490), Expect = 5e-51
Identities = 150/455 (32%), Positives = 193/455 (42%), Gaps = 42/455 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ GG C+C G+ + + C DVDEC NP +C G C NT GS+
Sbjct: 1203 NPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFV 1262
Query: 63 CLCEPGF-APTAAGYCADVDEC-AADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C+ G+ A C+DVDEC C C+N GSF C C G+ C
Sbjct: 1263 CHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECH 1320
Query: 120 DVDEC--EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC-----LGLKLGWGVSCQA 172
D+DEC +E R G C N PGS+RC C GF + DG C + + Q
Sbjct: 1321 DLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQC 1378
Query: 173 CPAQGSELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A G Y C G P++D+ D++EC A C GSCENL +RCIC+ GY
Sbjct: 1379 LNAPGG--YRCECEMGFDPTEDHRACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYE 1435
Query: 230 PD-ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET 288
D G C DI+EC C G C NT GS+ C CP+ P C D
Sbjct: 1436 LDRGGGNCTDINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFL 1494
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYVLDATAQRCL- 346
ETH +RGD E+ C + G + CEL + + T R L
Sbjct: 1495 ETH------DRGD--SGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLC 1546
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
G R+ ++ EC GL G L
Sbjct: 1547 PGGEGFQPNRIT-----VILEDI---DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 407 AT--CRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
T C D+DEC+ + +C GTC NT G+Y C CP
Sbjct: 1599 HTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 196 bits (477), Expect = 2e-49
Identities = 147/440 (33%), Positives = 184/440 (41%), Gaps = 47/440 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECA 84
PG + L + +D CR +C GRC T SY C C G+ G C DVDEC
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT 454
Query: 85 ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFR 143
+ S C G CVN G++ C C G++ T TR ACVDVDEC +C GRC NT GSF+
Sbjct: 455 S-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQ 513
Query: 144 CECLPGFTLSNDGRTCLG-LKLGWGVSC--QACPAQGSELYAVLCPEGPSKDNGG---AD 197
C C GF LS DG+ C+ + C C + ++ LC G GG D
Sbjct: 514 CVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGS-FSCLCKPGFLLAPGGHYCMD 572
Query: 198 INECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-R 255
I+EC PG C +G C N E +RC C G DG +C D G C R
Sbjct: 573 IDEC-QTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCAR 631
Query: 256 NTAGSFT---CVC--PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G+ T C C P+ EP QLC + E + G
Sbjct: 632 PFPGTVTKSECCCANPDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDP 690
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPEL 369
E+ C NG C N G + C C LGY A+ + C D + + D G C+ +
Sbjct: 691 EV---CANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGS- 746
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + D C+DVDEC S C G C N
Sbjct: 747 ---YSCSCPPGFHFWQ-------------------DTEICKDVDECLSSP--CVSGVCRN 782
Query: 430 TDGSYRCDCPPGLTLDSTGT 449
GSY C C PG LD +GT
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT 802
Score = 193 bits (471), Expect = 9e-49
Identities = 109/272 (40%), Positives = 138/272 (50%), Gaps = 14/272 (5%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G C N G F C C+ GY + C D+DEC P+ C C+NT GS+ C C
Sbjct: 2373 LCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSC 2431
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DEC + CVN+ G+F C C G+ T AC D DEC
Sbjct: 2432 PRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGF--TQHHQACFDNDEC 2489
Query: 125 EEQ-RVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQ-ACPAQGSEL 180
Q C +G CHNTPGSFRCEC GFTL + G C + G CQ C Q
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGG- 2548
Query: 181 YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLC 236
Y CP+G ++ + A D NEC P C SC N G+RC+C G+ D A G C
Sbjct: 2549 YRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGC 2608
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
+D+DEC + C+ C NT G F C CP+G
Sbjct: 2609 QDVDECAGRRGPCS-YSCANTPGGFLCGCPQG 2639
Score = 187 bits (456), Expect = 6e-47
Identities = 155/470 (32%), Positives = 194/470 (41%), Gaps = 88/470 (18%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C NG C+N G + C C PG+ + +C+DVDEC +P C G CRN AGSYT
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYT 788
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRC-VNSEGS---FQCVCEAG--------- 108
C C PG +G +C D + + RC VN +G+ +C G
Sbjct: 789 CKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCER 848
Query: 109 --YRPTATRG-------ACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
P RG C DV+ECE VC NGRC NT GSFRCEC G L GR
Sbjct: 849 CEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRL 908
Query: 159 CLGLKLGWGVSCQACPAQGSE-LYAVLCPEGPSKDNGGADINECTAVP-GACPHGSCENL 216
C+ ++L + C + E V P D I V ACP E+L
Sbjct: 909 CVDVRL------EPCFLRWDEDECGVTLPGKYRMDFCCCSIGAVWGVECEACP--DPESL 960
Query: 217 EPGYRCICDPGYHP----DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE 272
E C G+ +D++EC + C G CRNT GSF C C G +
Sbjct: 961 EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALD 1020
Query: 273 PELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECEC 332
+ + C DIDEC I P C G C+NT G FECEC
Sbjct: 1021 AQERNCTDIDECR----------------ISPDL---------CGQGTCVNTPGSFECEC 1055
Query: 333 ELGYVLD-ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
GY + C+D VD E A LL R C + GS
Sbjct: 1056 FPGYESGFMLMKNCMD----------VD---ECARDPLLCRGGTCTNTD---GSYKCQCP 1099
Query: 392 XXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
KG A C D+DEC+LS LC G CVN G+++C C G
Sbjct: 1100 PGHELTAKGTA------CEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAG 1143
Score = 176 bits (428), Expect = 2e-43
Identities = 115/324 (35%), Positives = 143/324 (44%), Gaps = 42/324 (12%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADV 80
+C G +EG RDVDECR +C G C N+ GS+ C C+ G+ P A A C D+
Sbjct: 2350 LCPHGSGYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC+ C N++GSF C C GY C D+DEC ++ C NT G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVG 2466
Query: 141 SFRCECLPGFTLSN----DGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG---PSKDN 193
+F C C PGFT + D C G GS + C +G S +
Sbjct: 2467 AFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGS--FRCECHQGFTLVSSGH 2524
Query: 194 GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSYCAGG 252
G D+NEC P C HG C+N GYRC C G+ + C D +EC + C
Sbjct: 2525 GCEDVNECDG-PHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSA 2582
Query: 253 QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTEL 312
CRNT G F CVCP G + L C+D+DEC G RG
Sbjct: 2583 SCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG-----------RRG------------ 2619
Query: 313 ASPCDNGRCINTHGGFECECELGY 336
PC C NT GGF C C GY
Sbjct: 2620 --PCSYS-CANTPGGFLCGCPQGY 2640
Score = 174 bits (424), Expect = 5e-43
Identities = 131/455 (28%), Positives = 188/455 (41%), Gaps = 75/455 (16%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
G++ + D+DEC++ P +C+ G C NT GS+ C C PG+ + C D+DEC+
Sbjct: 1551 GFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECS 1610
Query: 85 A-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC---RNGRCHNTPG 140
S+C G C N+ G++ CVC A Y C+D+ + VC NG C N
Sbjct: 1611 THSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM----RKSVCFRHYNGTCQNELA 1666
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLG--WGVSCQACPAQGSELYAVLC-PEGPS-----KD 192
F ++ C +G W C+ACP S Y +LC + P
Sbjct: 1667 ---------FNVTRK-MCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHT 1716
Query: 193 NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYC-A 250
DI+EC +P C +G C N +RC C G++ ++ L C D+DEC +S C
Sbjct: 1717 GKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ 1776
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
C N GS+ C C G + P C G E
Sbjct: 1777 NADCINIPGSYRCKCTRGYKLSPG-------GACVGRNECR------------------- 1810
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRR----GSCWRRVVDGQC 362
E+ + C +G C++T G + C C G+ A C+D +R+ G+C + C
Sbjct: 1811 EIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNC 1870
Query: 363 EAAAPELLLR--------QECCCSVG--LAWGSXXXXXXXXXXXXXKGF-AKLDGATCRD 411
P ++ EC VG +G GF DG C D
Sbjct: 1871 -LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD 1929
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+EC A C GTC N +GS+RC CPPG + S
Sbjct: 1930 TNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQS 1964
Score = 174 bits (424), Expect = 5e-43
Identities = 126/387 (32%), Positives = 161/387 (41%), Gaps = 66/387 (17%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-----------CR----DNPRVCR 50
+C NG C N G F C C G++ C D+ + CR + V R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 51 RGRCRNTAGSYTCLCE----PG------FAPTAAGYCA---DVDEC-AADSMCKGGRCVN 96
C + CE PG P +GY A DVDEC +C G C+N
Sbjct: 2322 AECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECIN 2381
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S GSF+C C+AGY P AT C+D+DEC + C NT GSF C C G+ L DG
Sbjct: 2382 SLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Query: 157 RTCLGLK--LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGAC-PHGS 212
RTC L +CQ + CP G ++ + D +EC+A PG C HG
Sbjct: 2442 RTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGH 2501
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
C N +RC C G+ + G C D++ECD C G C+N G + C CP+G
Sbjct: 2502 CHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQ 2559
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ C D +EC PPT C + C NT GGF C
Sbjct: 2560 HSQWAQCVDENECALS---------------PPT----------CGSASCRNTLGGFRCV 2594
Query: 332 CELGYVLDATAQRCLD-----NRRGSC 353
C G+ D C D RRG C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPC 2621
Score = 171 bits (416), Expect = 4e-42
Identities = 131/471 (27%), Positives = 182/471 (38%), Gaps = 63/471 (13%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C G C N G F+C C PGY +C D+DEC + +C G C NT G+YTC+
Sbjct: 1572 GLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCV 1631
Query: 65 CEPGFAPTAAG-YCADVDECAA----DSMCKGGRCVNSEGSFQCVCEAGYRPTATR--GA 117
C + G C D+ + + C+ N C C R A
Sbjct: 1632 CPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRK-MCCCSYNIGQAWNRPCEA 1690
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
C + Q +C N PG F + G L D + G+ G
Sbjct: 1691 CPTPISPDYQILCGN----QAPG-FLTDIHTGKPLDIDECGEIPAICANGICINQI---G 1742
Query: 178 SELYAVLCPEGPSKDN---GGADINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDAD 233
S + CP G + ++ D++EC + C + C N+ YRC C GY
Sbjct: 1743 S--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPG 1800
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE----GETE 289
G C +EC + C+ G C +T GS+ C+C G + + LC DIDEC+ G
Sbjct: 1801 GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT 1860
Query: 290 THYIESDY-----------ERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
I Y GD T + C G C+NT G F C C+ G+ L
Sbjct: 1861 CKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFEL 1920
Query: 339 DATAQRCLD-NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
A + C+D N S + G C+ C C G
Sbjct: 1921 TADGKNCVDTNECLSLAGTCLPGTCQNLEGSF----RCICPPGF---------------- 1960
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
++ C D+DEC+ LC GTC N+ GS++C CPPG L G
Sbjct: 1961 -----QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006
Score = 170 bits (414), Expect = 8e-42
Identities = 104/316 (32%), Positives = 141/316 (44%), Gaps = 39/316 (12%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGS 60
+ +GG+C G C N +G F+C+C G+E +G C D +EC + +C G C N GS
Sbjct: 494 IVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATST-MCVNGVCLNEDGS 552
Query: 61 YTCLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR--------- 110
++CLC+PGF G YC D+DEC +C G C N+EGSF+C C G
Sbjct: 553 FSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCV 612
Query: 111 PTATRGAC---VDVDEC---------EEQRVCRN-----GR-CHNTPGS----FRCECLP 148
T R C ++ C + + C N G C P F+ C
Sbjct: 613 DTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSS 672
Query: 149 GFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVP 205
G ++ DGR L V Y +C G G D++EC
Sbjct: 673 GLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732
Query: 206 GACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCV 264
C +G C+N Y C C PG+H D +C+D+DEC S C G CRN AGS+TC
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC--LSSPCVSGVCRNLAGSYTCK 790
Query: 265 CPEGTRHEPELQLCRD 280
C G+R +P C D
Sbjct: 791 CGPGSRLDPSGTFCLD 806
Score = 161 bits (392), Expect = 3e-39
Identities = 143/482 (29%), Positives = 185/482 (38%), Gaps = 85/482 (17%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G+CTNG+C N DG F C C GY G C D DEC C +G C N G +
Sbjct: 2091 NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNVIGGFE 2149
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF P C D+DEC+ + + RC N+EGS+ C C AGY C DVD
Sbjct: 2150 CACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVD 2209
Query: 123 ECEE-QRVC--RNGRCHNTPGSFRCECLPGF-TLSNDGRTCLGLKLGWGVSCQACPAQGS 178
EC + Q+ C R C N G+F C C PG L G C C AQ
Sbjct: 2210 ECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC--------TDDNECHAQPD 2261
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
LC G + G+ +C P C ++ G P + +CR
Sbjct: 2262 -----LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG------PCFAEVLQTMCR 2310
Query: 238 DI---DECDMHQSYCAGG------QCR----NTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
+ E C GG +C ++ +CP G+ + E RD+DEC
Sbjct: 2311 SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE---GRDVDEC 2367
Query: 285 --------EGE--TETHYIESDYERGDIPPTFPTR-------TELASPCDNGRCINTHGG 327
GE + G P T +++ PC C NT G
Sbjct: 2368 RMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGS 2426
Query: 328 FECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
F C C GY+L+ + C D C R C+ + C C
Sbjct: 2427 FLCSCPRGYLLEEDGRTCKD--LDECTSR--QHNCQFLCVNTVGAFTCRCP--------- 2473
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDS 446
GF + A C D DEC+ C A G C NT GS+RC+C G TL S
Sbjct: 2474 -----------PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 447 TG 448
+G
Sbjct: 2522 SG 2523
Score = 155 bits (375), Expect = 4e-37
Identities = 138/468 (29%), Positives = 183/468 (39%), Gaps = 91/468 (19%)
Query: 12 CKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
CKN+ G F C+C PG G C D +EC P +C GRC NTAGS+ C C+ GF
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 71 PTAA-GYCADVDE--CAADSMCKGGRCVNSEGSF----QCVCEAG--------------- 108
P+ C D+ + C A+ + R ++S +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 109 --YRPTATRGACV-----DVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
YR G+ DVDEC +C +G C N+ GSFRC C G+T TCL
Sbjct: 2345 SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCL 2404
Query: 161 GLKLGWGVS--CQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ V C + CP G + G D++ECT+ C C N
Sbjct: 2405 DMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVN 2463
Query: 216 LEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPE 274
+ C C PG+ C D DEC C A G C NT GSF C C +G
Sbjct: 2464 TVGAFTCRCPPGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSS 2522
Query: 275 LQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECEL 334
C D++EC+G P R C +G C N GG+ C C
Sbjct: 2523 GHGCEDVNECDG--------------------PHR------CQHG-CQNQLGGYRCSCPQ 2555
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXX 393
G+ + +C+D C + C +A+ L C C G +
Sbjct: 2556 GFTQHSQWAQCVDENE--C--ALSPPTCGSASCRNTLGGFRCVCPSGFDFDQA------- 2604
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
L G C+DVDECA C+ +C NT G + C CP G
Sbjct: 2605 ----------LGG--CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQG 2639
Score = 145 bits (351), Expect = 3e-34
Identities = 82/235 (34%), Positives = 111/235 (47%), Gaps = 14/235 (5%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+CKN G F C C GY +G C+D+DEC C+ C NT G++TC C PGF
Sbjct: 2419 LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFT 2477
Query: 71 PTAAGYCADVDECAADSMCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
C D DEC+A G G C N+ GSF+C C G+ ++ C DV+EC+
Sbjct: 2478 QHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPH 2536
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL----YAVL 184
C++G C N G +RC C GFT + C+ + +S C + + +
Sbjct: 2537 RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVD-ENECALSPPTCGSASCRNTLGGFRCV 2594
Query: 185 CPEGPSKDN--GGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
CP G D GG D++EC G C + SC N G+ C C GY G C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHC 2648
Score = 123 bits (296), Expect = 1e-27
Identities = 69/186 (37%), Positives = 88/186 (47%), Gaps = 7/186 (3%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C +G C N G F C C G+ S G C DV+EC D P C+ G C+N G Y C
Sbjct: 2494 GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHG-CQNQLGGYRC 2551
Query: 64 LCEPGFAPTAA-GYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C GF + C D +ECA + C C N+ G F+CVC +G+ G C DV
Sbjct: 2552 SCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
DEC +R + C NTPG F C C G+ + G G LG+ Q P + L
Sbjct: 2612 DECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSG--LGFSPGPQDTPDKEELLS 2669
Query: 182 AVLCPE 187
+ C E
Sbjct: 2670 SEACYE 2675
Score = 113 bits (273), Expect = 9e-25
Identities = 119/476 (25%), Positives = 167/476 (35%), Gaps = 73/476 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C+N+ G F CIC GYE G C D++EC D P C G C NT GSY C
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLC 1469
Query: 64 LCEPGFAPTAAGY-CADV--DECAADSMCKGGRCVNSEGSF-------QCVCEAGYRPTA 113
C F +G C D C ++ +G ++ C C G
Sbjct: 1470 SCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGN 1529
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSF--------RCECLPGFTLSNDGRTCLGLKLG 165
C + E + +C G P C+ LPG D G
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQ-PNRITVILEDIDECQELPGLCQGGDCVNTFG---- 1584
Query: 166 WGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICD 225
C+ P + +C DI+EC+ C G+C N Y C+C
Sbjct: 1585 -SFQCECPPGYHLSEHTRICE----------DIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 226 PGY-HPDADGLCRDIDECDMHQSYCAGGQCRNT-AGSFT---CVCPE--GTRHEPELQLC 278
Y + C D+ + + Y G C+N A + T C C G + C
Sbjct: 1634 AEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEAC 1691
Query: 279 R-----DIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECE 333
D G ++ +D G P E+ + C NG CIN G F CEC
Sbjct: 1692 PTPISPDYQILCGNQAPGFL-TDIHTGK-PLDIDECGEIPAICANGICINQIGSFRCECP 1749
Query: 334 LGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXX 393
G+ ++ C D C R Q A + C C+
Sbjct: 1750 AGFNYNSILLACEDV--DECGSRESPCQQNADCINIPGSYRCKCT--------------- 1792
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+G+ G C +EC +C+ G C++T+GSY C C G + T
Sbjct: 1793 -----RGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQT 1843
Score = 75.8 bits (178), Expect = 3e-13
Identities = 48/138 (34%), Positives = 63/138 (45%), Gaps = 9/138 (6%)
Query: 316 CDNG-RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NG RCI G C C G+ + +R D R G C+ +V C+ L+ +
Sbjct: 155 CHNGGRCI---GPNRCACVYGF-MGPQCER--DYRTGPCFGQVGPEGCQHQLTGLVCTKA 208
Query: 375 -CCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVNTDG 432
CC +VG AWG +GF + C+DVDEC LC GG+CVN G
Sbjct: 209 LCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVG 268
Query: 433 SYRCDCPPGLTLDSTGTA 450
S+ C CP G L + A
Sbjct: 269 SFHCRCPVGHRLSDSSAA 286
Score = 70.5 bits (165), Expect = 1e-11
Identities = 79/272 (29%), Positives = 97/272 (35%), Gaps = 45/272 (16%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT 72
N+ G F C PG+ + + C V CR R C G C C C G
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV-VPICR---RACGEGFCSQPN---LCTCADGTLAP 110
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
+ G C+ M GG C + C+C+ GY T D R C N
Sbjct: 111 SCGVSRG-SGCSVSCM-NGGTCRGAS----CLCQKGYTGTVCGQPICD-------RGCHN 157
Query: 133 G-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
G RC G RC C+ GF G C+ G + + PEG
Sbjct: 158 GGRCI---GPNRCACVYGFM---------------GPQCERDYRTGP-CFGQVGPEGCQH 198
Query: 192 DNGGADINE--CTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSY 248
G + C A G CE L P C G+ P+ G C+D+DEC
Sbjct: 199 QLTGLVCTKALCCATVGRAWGLPCE-LCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGL 257
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
C GG C N GSF C CP G R C D
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 61.7 bits (143), Expect = 5e-09
Identities = 23/70 (32%), Positives = 35/70 (50%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C+N G F C C +G+ L ++ C D R G+C+ + G+C R++C
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQC 317
Query: 376 CCSVGLAWGS 385
CC G W +
Sbjct: 318 CCDRGRCWAA 327
Score = 55.6 bits (128), Expect = 3e-07
Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C G+ P GAC DVDEC+ +C+ G C N GSF C C G LS+ C +
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Query: 164 LG 165
G
Sbjct: 292 AG 293
Score = 41.5 bits (93), Expect = 0.006
Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
C DVDEC S C G CVN G+Y C C PG T A
Sbjct: 447 CIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQA 486
Score = 40.3 bits (90), Expect = 0.014
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 5/68 (7%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCR-NTAGSYT- 62
G+C G C N+ G F C C G+ A C D V GRC + AG YT
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDY-RAGACFSVLFGGRCAGDLAGHYTR 314
Query: 63 --CLCEPG 68
C C+ G
Sbjct: 315 RQCCCDRG 322
>AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 308 bits (756), Expect = 3e-83
Identities = 170/465 (36%), Positives = 236/465 (50%), Gaps = 39/465 (8%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C +G C NI G + C C PG+++ C DVDEC + +C GRC NT GS+ C+C
Sbjct: 458 CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + G C D +ECA +MC G C+N +GSF C+C+ G+ C+D+DEC+
Sbjct: 518 AGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ 577
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG---WGV----SCQACPAQGS 178
+C NG C NT GSFRC+CL G + DGR C+ + +G SC A P G+
Sbjct: 578 TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC-ARPFPGT 636
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
+ C P D+G + C P S E ++ +C G DG RD
Sbjct: 637 VTKSECCCANP--DHGFGE--PCQLCPA---KNSAE-----FQALCSSGLGITTDG--RD 682
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIES 295
I+EC + CA G C N GS+ CVC G + C D+DEC + + + ++
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQN 742
Query: 296 D--YERGDIPPTFP--TRTE--------LASPCDNGRCINTHGGFECECELGYVLDATAQ 343
PP F TE L+SPC +G C N G + C+C G LD +
Sbjct: 743 SPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGT 802
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
CLD+ +G+CW ++ + +CE LR ECC ++G AWGS +GFA+
Sbjct: 803 FCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS-PCERCEIDPACARGFAR 861
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+ G TC DV+EC +C G CVNT GS+RC+CP GL LD++G
Sbjct: 862 MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 263 bits (644), Expect = 1e-69
Identities = 165/493 (33%), Positives = 222/493 (45%), Gaps = 55/493 (11%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+CT+G C+N G F C C G+ ++ C D+DECR +P +C +G C NT GS+ C
Sbjct: 995 GLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 65 CEPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG+ C DVDECA D +C+GG C N++GS++C C G+ TA AC D+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDI 1114
Query: 122 DECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQ 176
DEC +C +G+C N G+F+C C GF + D + C+ + G +
Sbjct: 1115 DECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE 1174
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
GS Y C +G S G AD++EC P C G C N+ G+RC+C G+ D
Sbjct: 1175 GS--YRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C D+DECD++ C G C NT GSF C C G C D+DEC E H
Sbjct: 1233 MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC--EVGGHN 1290
Query: 293 IESDYERGDIPPTFPTR---------------TELASP---CD-NGRCINTHGGFECECE 333
+S +IP +F R E S C G C+N G + C C
Sbjct: 1291 CDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 334 LGYVLDA----TAQRCLDN----RRGSCWRRVVDGQCEAAA---PELLLR-----QECCC 377
G+ D C +N G C +CE P R EC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ 1410
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYR 435
A+GS G+ +LD G C D++ECA C G C+NT GSY
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGY-ELDRGGGNCTDINECADPVN-CINGVCINTPGSYL 1468
Query: 436 CDCPPGLTLDSTG 448
C CP L+ +G
Sbjct: 1469 CSCPQDFELNPSG 1481
Score = 251 bits (614), Expect = 4e-66
Identities = 154/458 (33%), Positives = 196/458 (42%), Gaps = 60/458 (13%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RG-RCRNTAGSYTCLCEPGF 69
C N +G + C C GY +GA+CRDVDEC D + C RG C+N G++ C+C PG
Sbjct: 2181 CHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGM 2240
Query: 70 APTAAGY--CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
P C D +EC A +C GRCVN+ GSF+C C+ G++P+ T C D+
Sbjct: 2241 RPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDI----- 2295
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
R G C C L + + C G GWG C+ CP G+ Y LC
Sbjct: 2296 ----RQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLC 2351
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
P G G D++EC + C HG C N +RC C GY PDA C D+DEC
Sbjct: 2352 PHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQ 2411
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI-- 302
C C+NT GSF C CP G E + + C+D+DEC G
Sbjct: 2412 VPKPCT-FLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTC 2470
Query: 303 --PPTFPTRTELA----------SPCD-NGRCINTHGGFECECELGYVLDATAQRCLDNR 349
PP F + PC +G C NT G F CEC G+ L ++ C D
Sbjct: 2471 RCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED-- 2528
Query: 350 RGSCWRRVVDG--QCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA 407
C DG +C+ L C C G S A
Sbjct: 2529 VNEC-----DGPHRCQHGCQNQLGGYRCSCPQGFTQHS-------------------QWA 2564
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
C D +ECALS C +C NT G +RC CP G D
Sbjct: 2565 QCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFD 2602
Score = 236 bits (578), Expect = 1e-61
Identities = 158/481 (32%), Positives = 217/481 (45%), Gaps = 47/481 (9%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G C G C+N++G F CIC PG++ S+ C D+DEC + P +C G C N+ GS+ CL
Sbjct: 1938 GTCLPGTCQNLEGSFRCICPPGFQVQSDH--CIDIDECSEEPNLCLFGTCTNSPGSFQCL 1995
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCV--NSEGSFQCVCEAGYRPTATRGACVDV 121
C PGF + G+ C D + + + G+C + + + C RP G
Sbjct: 1996 CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWG----- 2050
Query: 122 DECEEQRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D CE +C F +PG S + G + GS
Sbjct: 2051 DPCE---LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGS- 2106
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ CP G S D G D +EC+ V C G+C N+ G+ C C G+ P C
Sbjct: 2107 -FRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCTNVIGGFECACADGFEPGLMMTC 2164
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETETHY--I 293
DIDEC ++ CA +C NT GS+ C CP G + +CRD+DEC +G+ + H +
Sbjct: 2165 EDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM 2223
Query: 294 ESDYERGDI----PP---TFPTRTE--------LASP--CDNGRCINTHGGFECECELGY 336
E G PP P E A P C NGRC+NT G F C+C+ G+
Sbjct: 2224 ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGF 2283
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEA--AAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
T C D R+G C+ V+ C + ++ E + R ECCC G WG
Sbjct: 2284 QPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPG 2343
Query: 395 XXXXKGFAKL-DGATC--RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
+ G T RDVDEC + A LCA G C+N+ GS+RC C G T D+T T
Sbjct: 2344 TSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Query: 452 L 452
L
Sbjct: 2404 L 2404
Score = 235 bits (574), Expect = 3e-61
Identities = 148/442 (33%), Positives = 197/442 (44%), Gaps = 46/442 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDEC 83
PG+ + D+DEC + P +C G C N GS+ C C GF + C DVDEC
Sbjct: 1708 PGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC 1767
Query: 84 AA-DSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPG 140
+ +S C + C+N GS++C C GY+ + GACV +EC E VC +G C +T G
Sbjct: 1768 GSRESPCQQNADCINIPGSYRCKCTRGYK-LSPGGACVGRNECREIPNVCSHGDCMDTEG 1826
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG-SELYAVLCPEGPSKDNGG--AD 197
S+ C C GF S D C+ + C + Y LC G + G D
Sbjct: 1827 SYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVD 1886
Query: 198 INECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCR 255
+ECT + G C G C N + C+C G+ ADG C D +EC C G C+
Sbjct: 1887 FDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N GSF C+CP G + + C DIDEC E
Sbjct: 1947 NLEGSFRCICPPG--FQVQSDHCIDIDECSEEPNL------------------------- 1979
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C N+ G F+C C G+VL RC D R+ C+ R G+C + C
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 376 CCS--VGLAWGSXXXXXXXXXXXXXK-----GFAKLDGA--TCRDVDECALSAELCAGGT 426
CCS G WG + G + G + DV+ECA + +C G
Sbjct: 2040 CCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGV 2099
Query: 427 CVNTDGSYRCDCPPGLTLDSTG 448
CVNTDGS+RC+CP G +LD TG
Sbjct: 2100 CVNTDGSFRCECPFGYSLDFTG 2121
Score = 224 bits (548), Expect = 4e-58
Identities = 154/461 (33%), Positives = 202/461 (43%), Gaps = 58/461 (12%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG+C+N+ G + C+C GYE+G+ G C DVDEC N +C G C+N+ GSY+C C
Sbjct: 692 VCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSC 751
Query: 66 EPGF-APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
PGF C DVDEC + S C G C N GS+ C C G R + C+D
Sbjct: 752 PPGFHFWQDTEICKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD---- 806
Query: 125 EEQRVCRNGRCHNTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
G C RCE L G +L ++ C L WG C+ C +
Sbjct: 807 -----STKGTCWLKIQESRCEVNLQGASLRSE--CCATLGAAWGSPCERCEIDPA----- 854
Query: 184 LCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDI- 239
C G ++ G D+NEC + PG CP+G C N +RC C G DA G LC D+
Sbjct: 855 -CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVR 913
Query: 240 -DECDMH--QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET----ETHY 292
+ C + + C G C C G E + C D + E + +
Sbjct: 914 LEPCFLRWDEDEC-GVTLPGKYLMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGF 972
Query: 293 IESDYERGDIPPTFPTRTE---LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
D+ G P + E C +G C NT G F C C G+ LDA + C D
Sbjct: 973 ASRDFLSG--RPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD-- 1028
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
+D +C +P+L C G + GF + C
Sbjct: 1029 --------ID-ECR-ISPDL-------CGQGTCVNTPGSFECECFPGYESGFMLM--KNC 1069
Query: 410 RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
DVDECA LC GGTC NTDGSY+C CPPG L + GTA
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTA 1110
Score = 224 bits (547), Expect = 6e-58
Identities = 150/457 (32%), Positives = 195/457 (42%), Gaps = 72/457 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C N G F C+C+ G+E ++G C D +EC C G C+N GS+ C
Sbjct: 1895 GQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRC 1954
Query: 64 LCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PGF + +C D+DEC+ + ++C G C NS GSFQC+C G+ + C D
Sbjct: 1955 ICPPGF-QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDT- 2012
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSEL 180
R C + +C F + R C + GWG C+ CP +GS
Sbjct: 2013 --------RQSFCFTRFEAGKCSVPKAFNTTKT-RCCCSKRPGEGWGDPCELCPQEGSAA 2063
Query: 181 YAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
+ LCP G P D+ D+NEC PG C +G C N + +RC C GY D G+
Sbjct: 2064 FQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGIN 2123
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL-CRDIDECEGETETHYIE 294
C D DEC + C G C N G F C C +G EP L + C DIDEC
Sbjct: 2124 CVDTDECSVGHP-CGQGTCTNVIGGFECACADG--FEPGLMMTCEDIDEC---------- 2170
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCW 354
+ P A C N T G + C C GY L C D C
Sbjct: 2171 ------SLNPLL-----CAFRCHN-----TEGSYLCTCPAGYTLREDGAMCRD--VDEC- 2211
Query: 355 RRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA--TCRDV 412
DGQ + A + EC +G G L G+ C D
Sbjct: 2212 ---ADGQQDCHARGM----ECKNLIG-----------TFACVCPPGMRPLPGSGEGCTDD 2253
Query: 413 DECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+EC +LC G CVNT GS+RCDC G T T
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLT 2290
Score = 217 bits (529), Expect = 9e-56
Identities = 143/421 (33%), Positives = 184/421 (43%), Gaps = 61/421 (14%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDEC-AADSMCKGGRC 94
+DV+EC+ P +C G CRNT GS+ C C GFA A C D+DEC + +C G C
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ GSF+C C GY C+DVDEC + +CR G C NT GS++C+C PG L
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 153 SNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG-ADINECTAVPG 206
+ G C + L G+ + C G + D G DINEC G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 207 ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
C C N E YRC C GY DG C D+DEC+ + C G C N G C+C
Sbjct: 1165 GC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLC 1223
Query: 266 PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTH 325
+G P+++ C D+DEC D+ P C +G C NT
Sbjct: 1224 YDGFMATPDMRTCVDVDEC----------------DLNPHI---------CLHGDCENTK 1258
Query: 326 GGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
G F C C+LGY++ A C D C V C++ A L + C W
Sbjct: 1259 GSFVCHCQLGYMVRKGATGCSD--VDEC--EVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTL 444
DG C D+DEC C+ G C+N GSYRC C G
Sbjct: 1315 -------------------DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 445 D 445
D
Sbjct: 1356 D 1356
Score = 210 bits (513), Expect = 8e-54
Identities = 102/272 (37%), Positives = 143/272 (52%), Gaps = 12/272 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCL 64
+C NGIC N G F C C G+ S C DVDEC C++ C N GSY C
Sbjct: 1731 ICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 65 CEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G+ + G C +EC ++C G C+++EGS+ C+C G++ +A + C+D+DE
Sbjct: 1791 CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDE 1850
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP----AQGSE 179
C+ Q C NG C N GS+ C C PGF ++++G C+ + Q C +
Sbjct: 1851 CDRQ-PCGNGTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAG 1908
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ LC +G G D NEC ++ G C G+C+NLE +RCIC PG+ +D C
Sbjct: 1909 SFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDH-C 1967
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
DIDEC + C G C N+ GSF C+CP G
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPG 1999
Score = 206 bits (503), Expect = 1e-52
Identities = 161/471 (34%), Positives = 197/471 (41%), Gaps = 70/471 (14%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C G C N+ GGFEC C G+E G C D+DEC NP +C RC NT GSY C
Sbjct: 2133 GHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDIDECSLNPLLCAF-RCHNTEGSYLC 2190
Query: 64 LCEPGFAPTAAG-YCADVDECA---ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG-AC 118
C G+ G C DVDECA D +G C N G+F CVC G RP G C
Sbjct: 2191 TCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Query: 119 VDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
D +EC Q +C NGRC NT GSFRC+C GF S C ++ G C A
Sbjct: 2251 TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG---PCFA----- 2302
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLE-PG---YRCICDPGYHPDAD 233
E+ +C S + EC G CE PG YR +C G A+
Sbjct: 2303 -EVLQTMC-RSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE 2360
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G RD+DEC M CA G+C N+ GSF C C G + C D+DEC
Sbjct: 2361 G--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDEC--------- 2409
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD-----N 348
+++ PC C NT G F C C GY+L+ + C D +
Sbjct: 2410 ----------------SQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS 2452
Query: 349 RRGSCWRRVVD--GQCEAAAPELLLRQ--------ECCCSVGL--AWGSXXXXXXXXXXX 396
R+ +C V+ G P + EC G A G
Sbjct: 2453 RQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCE 2512
Query: 397 XXKGFAKLD-GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+GF + G C DV+EC C G C N G YRC CP G T S
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHS 2561
Score = 201 bits (490), Expect = 5e-51
Identities = 150/455 (32%), Positives = 193/455 (42%), Gaps = 42/455 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ GG C+C G+ + + C DVDEC NP +C G C NT GS+
Sbjct: 1203 NPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFV 1262
Query: 63 CLCEPGF-APTAAGYCADVDEC-AADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C+ G+ A C+DVDEC C C+N GSF C C G+ C
Sbjct: 1263 CHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECH 1320
Query: 120 DVDEC--EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC-----LGLKLGWGVSCQA 172
D+DEC +E R G C N PGS+RC C GF + DG C + + Q
Sbjct: 1321 DLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQC 1378
Query: 173 CPAQGSELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A G Y C G P++D+ D++EC A C GSCENL +RCIC+ GY
Sbjct: 1379 LNAPGG--YRCECEMGFDPTEDHRACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYE 1435
Query: 230 PD-ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET 288
D G C DI+EC C G C NT GS+ C CP+ P C D
Sbjct: 1436 LDRGGGNCTDINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFL 1494
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYVLDATAQRCL- 346
ETH +RGD E+ C + G + CEL + + T R L
Sbjct: 1495 ETH------DRGD--SGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLC 1546
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
G R+ ++ EC GL G L
Sbjct: 1547 PGGEGFQPNRIT-----VILEDI---DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 407 AT--CRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
T C D+DEC+ + +C GTC NT G+Y C CP
Sbjct: 1599 HTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 196 bits (477), Expect = 2e-49
Identities = 147/440 (33%), Positives = 184/440 (41%), Gaps = 47/440 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECA 84
PG + L + +D CR +C GRC T SY C C G+ G C DVDEC
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT 454
Query: 85 ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFR 143
+ S C G CVN G++ C C G++ T TR ACVDVDEC +C GRC NT GSF+
Sbjct: 455 S-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQ 513
Query: 144 CECLPGFTLSNDGRTCLG-LKLGWGVSC--QACPAQGSELYAVLCPEGPSKDNGG---AD 197
C C GF LS DG+ C+ + C C + ++ LC G GG D
Sbjct: 514 CVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGS-FSCLCKPGFLLAPGGHYCMD 572
Query: 198 INECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-R 255
I+EC PG C +G C N E +RC C G DG +C D G C R
Sbjct: 573 IDEC-QTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCAR 631
Query: 256 NTAGSFT---CVC--PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G+ T C C P+ EP QLC + E + G
Sbjct: 632 PFPGTVTKSECCCANPDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDP 690
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPEL 369
E+ C NG C N G + C C LGY A+ + C D + + D G C+ +
Sbjct: 691 EV---CANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGS- 746
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + D C+DVDEC S C G C N
Sbjct: 747 ---YSCSCPPGFHFWQ-------------------DTEICKDVDECLSSP--CVSGVCRN 782
Query: 430 TDGSYRCDCPPGLTLDSTGT 449
GSY C C PG LD +GT
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT 802
Score = 193 bits (471), Expect = 9e-49
Identities = 109/272 (40%), Positives = 138/272 (50%), Gaps = 14/272 (5%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G C N G F C C+ GY + C D+DEC P+ C C+NT GS+ C C
Sbjct: 2373 LCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSC 2431
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DEC + CVN+ G+F C C G+ T AC D DEC
Sbjct: 2432 PRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGF--TQHHQACFDNDEC 2489
Query: 125 EEQ-RVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQ-ACPAQGSEL 180
Q C +G CHNTPGSFRCEC GFTL + G C + G CQ C Q
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGG- 2548
Query: 181 YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLC 236
Y CP+G ++ + A D NEC P C SC N G+RC+C G+ D A G C
Sbjct: 2549 YRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGC 2608
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
+D+DEC + C+ C NT G F C CP+G
Sbjct: 2609 QDVDECAGRRGPCS-YSCANTPGGFLCGCPQG 2639
Score = 187 bits (456), Expect = 6e-47
Identities = 156/473 (32%), Positives = 193/473 (40%), Gaps = 94/473 (19%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C NG C+N G + C C PG+ + +C+DVDEC +P C G CRN AGSYT
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYT 788
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRC-VNSEGS---FQCVCEAG--------- 108
C C PG +G +C D + + RC VN +G+ +C G
Sbjct: 789 CKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCER 848
Query: 109 --YRPTATRG-------ACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
P RG C DV+ECE VC NGRC NT GSFRCEC G L GR
Sbjct: 849 CEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRL 908
Query: 159 CLGLK-----LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSC 213
C+ ++ L W G L V C G EC ACP
Sbjct: 909 CVDVRLEPCFLRWDEDECGVTLPGKYLMDVCC-----CSIGAVWGVECE----ACP--DP 957
Query: 214 ENLEPGYRCICDPGYHP----DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT 269
E+LE C G+ +D++EC + C G CRNT GSF C C G
Sbjct: 958 ESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGF 1017
Query: 270 RHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFE 329
+ + + C DIDEC I P C G C+NT G FE
Sbjct: 1018 ALDAQERNCTDIDECR----------------ISPDL---------CGQGTCVNTPGSFE 1052
Query: 330 CECELGYVLD-ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXX 388
CEC GY + C+D VD E A LL R C + GS
Sbjct: 1053 CECFPGYESGFMLMKNCMD----------VD---ECARDPLLCRGGTCTNTD---GSYKC 1096
Query: 389 XXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
KG A C D+DEC+LS LC G CVN G+++C C G
Sbjct: 1097 QCPPGHELTAKGTA------CEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAG 1143
Score = 176 bits (428), Expect = 2e-43
Identities = 115/324 (35%), Positives = 143/324 (44%), Gaps = 42/324 (12%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADV 80
+C G +EG RDVDECR +C G C N+ GS+ C C+ G+ P A A C D+
Sbjct: 2350 LCPHGSGYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC+ C N++GSF C C GY C D+DEC ++ C NT G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVG 2466
Query: 141 SFRCECLPGFTLSN----DGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG---PSKDN 193
+F C C PGFT + D C G GS + C +G S +
Sbjct: 2467 AFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGS--FRCECHQGFTLVSSGH 2524
Query: 194 GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSYCAGG 252
G D+NEC P C HG C+N GYRC C G+ + C D +EC + C
Sbjct: 2525 GCEDVNECDG-PHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSA 2582
Query: 253 QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTEL 312
CRNT G F CVCP G + L C+D+DEC G RG
Sbjct: 2583 SCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG-----------RRG------------ 2619
Query: 313 ASPCDNGRCINTHGGFECECELGY 336
PC C NT GGF C C GY
Sbjct: 2620 --PCSYS-CANTPGGFLCGCPQGY 2640
Score = 174 bits (424), Expect = 5e-43
Identities = 131/455 (28%), Positives = 188/455 (41%), Gaps = 75/455 (16%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
G++ + D+DEC++ P +C+ G C NT GS+ C C PG+ + C D+DEC+
Sbjct: 1551 GFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECS 1610
Query: 85 A-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC---RNGRCHNTPG 140
S+C G C N+ G++ CVC A Y C+D+ + VC NG C N
Sbjct: 1611 THSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM----RKSVCFRHYNGTCQNELA 1666
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLG--WGVSCQACPAQGSELYAVLC-PEGPS-----KD 192
F ++ C +G W C+ACP S Y +LC + P
Sbjct: 1667 ---------FNVTRK-MCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHT 1716
Query: 193 NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYC-A 250
DI+EC +P C +G C N +RC C G++ ++ L C D+DEC +S C
Sbjct: 1717 GKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ 1776
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
C N GS+ C C G + P C G E
Sbjct: 1777 NADCINIPGSYRCKCTRGYKLSPG-------GACVGRNECR------------------- 1810
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRR----GSCWRRVVDGQC 362
E+ + C +G C++T G + C C G+ A C+D +R+ G+C + C
Sbjct: 1811 EIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNC 1870
Query: 363 EAAAPELLLR--------QECCCSVG--LAWGSXXXXXXXXXXXXXKGF-AKLDGATCRD 411
P ++ EC VG +G GF DG C D
Sbjct: 1871 -LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD 1929
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+EC A C GTC N +GS+RC CPPG + S
Sbjct: 1930 TNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQS 1964
Score = 174 bits (424), Expect = 5e-43
Identities = 126/387 (32%), Positives = 161/387 (41%), Gaps = 66/387 (17%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-----------CR----DNPRVCR 50
+C NG C N G F C C G++ C D+ + CR + V R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 51 RGRCRNTAGSYTCLCE----PG------FAPTAAGYCA---DVDEC-AADSMCKGGRCVN 96
C + CE PG P +GY A DVDEC +C G C+N
Sbjct: 2322 AECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECIN 2381
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S GSF+C C+AGY P AT C+D+DEC + C NT GSF C C G+ L DG
Sbjct: 2382 SLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Query: 157 RTCLGLK--LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGAC-PHGS 212
RTC L +CQ + CP G ++ + D +EC+A PG C HG
Sbjct: 2442 RTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGH 2501
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
C N +RC C G+ + G C D++ECD C G C+N G + C CP+G
Sbjct: 2502 CHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQ 2559
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ C D +EC PPT C + C NT GGF C
Sbjct: 2560 HSQWAQCVDENECALS---------------PPT----------CGSASCRNTLGGFRCV 2594
Query: 332 CELGYVLDATAQRCLD-----NRRGSC 353
C G+ D C D RRG C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPC 2621
Score = 171 bits (416), Expect = 4e-42
Identities = 131/471 (27%), Positives = 182/471 (38%), Gaps = 63/471 (13%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C G C N G F+C C PGY +C D+DEC + +C G C NT G+YTC+
Sbjct: 1572 GLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCV 1631
Query: 65 CEPGFAPTAAG-YCADVDECAA----DSMCKGGRCVNSEGSFQCVCEAGYRPTATR--GA 117
C + G C D+ + + C+ N C C R A
Sbjct: 1632 CPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRK-MCCCSYNIGQAWNRPCEA 1690
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
C + Q +C N PG F + G L D + G+ G
Sbjct: 1691 CPTPISPDYQILCGN----QAPG-FLTDIHTGKPLDIDECGEIPAICANGICINQI---G 1742
Query: 178 SELYAVLCPEGPSKDN---GGADINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDAD 233
S + CP G + ++ D++EC + C + C N+ YRC C GY
Sbjct: 1743 S--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPG 1800
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE----GETE 289
G C +EC + C+ G C +T GS+ C+C G + + LC DIDEC+ G
Sbjct: 1801 GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT 1860
Query: 290 THYIESDY-----------ERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
I Y GD T + C G C+NT G F C C+ G+ L
Sbjct: 1861 CKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFEL 1920
Query: 339 DATAQRCLD-NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
A + C+D N S + G C+ C C G
Sbjct: 1921 TADGKNCVDTNECLSLAGTCLPGTCQNLEGSF----RCICPPGF---------------- 1960
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
++ C D+DEC+ LC GTC N+ GS++C CPPG L G
Sbjct: 1961 -----QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006
Score = 170 bits (414), Expect = 8e-42
Identities = 104/316 (32%), Positives = 141/316 (44%), Gaps = 39/316 (12%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGS 60
+ +GG+C G C N +G F+C+C G+E +G C D +EC + +C G C N GS
Sbjct: 494 IVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATST-MCVNGVCLNEDGS 552
Query: 61 YTCLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR--------- 110
++CLC+PGF G YC D+DEC +C G C N+EGSF+C C G
Sbjct: 553 FSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCV 612
Query: 111 PTATRGAC---VDVDEC---------EEQRVCRN-----GR-CHNTPGS----FRCECLP 148
T R C ++ C + + C N G C P F+ C
Sbjct: 613 DTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSS 672
Query: 149 GFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVP 205
G ++ DGR L V Y +C G G D++EC
Sbjct: 673 GLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732
Query: 206 GACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCV 264
C +G C+N Y C C PG+H D +C+D+DEC S C G CRN AGS+TC
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC--LSSPCVSGVCRNLAGSYTCK 790
Query: 265 CPEGTRHEPELQLCRD 280
C G+R +P C D
Sbjct: 791 CGPGSRLDPSGTFCLD 806
Score = 161 bits (392), Expect = 3e-39
Identities = 143/482 (29%), Positives = 185/482 (38%), Gaps = 85/482 (17%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G+CTNG+C N DG F C C GY G C D DEC C +G C N G +
Sbjct: 2091 NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNVIGGFE 2149
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF P C D+DEC+ + + RC N+EGS+ C C AGY C DVD
Sbjct: 2150 CACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVD 2209
Query: 123 ECEE-QRVC--RNGRCHNTPGSFRCECLPGF-TLSNDGRTCLGLKLGWGVSCQACPAQGS 178
EC + Q+ C R C N G+F C C PG L G C C AQ
Sbjct: 2210 ECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC--------TDDNECHAQPD 2261
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
LC G + G+ +C P C ++ G P + +CR
Sbjct: 2262 -----LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG------PCFAEVLQTMCR 2310
Query: 238 DI---DECDMHQSYCAGG------QCR----NTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
+ E C GG +C ++ +CP G+ + E RD+DEC
Sbjct: 2311 SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE---GRDVDEC 2367
Query: 285 --------EGE--TETHYIESDYERGDIPPTFPTR-------TELASPCDNGRCINTHGG 327
GE + G P T +++ PC C NT G
Sbjct: 2368 RMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGS 2426
Query: 328 FECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
F C C GY+L+ + C D C R C+ + C C
Sbjct: 2427 FLCSCPRGYLLEEDGRTCKD--LDECTSR--QHNCQFLCVNTVGAFTCRCP--------- 2473
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDS 446
GF + A C D DEC+ C A G C NT GS+RC+C G TL S
Sbjct: 2474 -----------PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 447 TG 448
+G
Sbjct: 2522 SG 2523
Score = 155 bits (375), Expect = 4e-37
Identities = 138/468 (29%), Positives = 183/468 (39%), Gaps = 91/468 (19%)
Query: 12 CKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
CKN+ G F C+C PG G C D +EC P +C GRC NTAGS+ C C+ GF
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 71 PTAA-GYCADVDE--CAADSMCKGGRCVNSEGSF----QCVCEAG--------------- 108
P+ C D+ + C A+ + R ++S +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 109 --YRPTATRGACV-----DVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
YR G+ DVDEC +C +G C N+ GSFRC C G+T TCL
Sbjct: 2345 SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCL 2404
Query: 161 GLKLGWGVS--CQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ V C + CP G + G D++ECT+ C C N
Sbjct: 2405 DMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVN 2463
Query: 216 LEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPE 274
+ C C PG+ C D DEC C A G C NT GSF C C +G
Sbjct: 2464 TVGAFTCRCPPGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSS 2522
Query: 275 LQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECEL 334
C D++EC+G P R C +G C N GG+ C C
Sbjct: 2523 GHGCEDVNECDG--------------------PHR------CQHG-CQNQLGGYRCSCPQ 2555
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXX 393
G+ + +C+D C + C +A+ L C C G +
Sbjct: 2556 GFTQHSQWAQCVDENE--C--ALSPPTCGSASCRNTLGGFRCVCPSGFDFDQA------- 2604
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
L G C+DVDECA C+ +C NT G + C CP G
Sbjct: 2605 ----------LGG--CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQG 2639
Score = 145 bits (351), Expect = 3e-34
Identities = 82/235 (34%), Positives = 111/235 (47%), Gaps = 14/235 (5%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+CKN G F C C GY +G C+D+DEC C+ C NT G++TC C PGF
Sbjct: 2419 LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFT 2477
Query: 71 PTAAGYCADVDECAADSMCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
C D DEC+A G G C N+ GSF+C C G+ ++ C DV+EC+
Sbjct: 2478 QHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPH 2536
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL----YAVL 184
C++G C N G +RC C GFT + C+ + +S C + + +
Sbjct: 2537 RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVD-ENECALSPPTCGSASCRNTLGGFRCV 2594
Query: 185 CPEGPSKDN--GGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
CP G D GG D++EC G C + SC N G+ C C GY G C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHC 2648
Score = 123 bits (296), Expect = 1e-27
Identities = 69/186 (37%), Positives = 88/186 (47%), Gaps = 7/186 (3%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C +G C N G F C C G+ S G C DV+EC D P C+ G C+N G Y C
Sbjct: 2494 GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHG-CQNQLGGYRC 2551
Query: 64 LCEPGFAPTAA-GYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C GF + C D +ECA + C C N+ G F+CVC +G+ G C DV
Sbjct: 2552 SCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
DEC +R + C NTPG F C C G+ + G G LG+ Q P + L
Sbjct: 2612 DECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSG--LGFSPGPQDTPDKEELLS 2669
Query: 182 AVLCPE 187
+ C E
Sbjct: 2670 SEACYE 2675
Score = 113 bits (273), Expect = 9e-25
Identities = 119/476 (25%), Positives = 167/476 (35%), Gaps = 73/476 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C+N+ G F CIC GYE G C D++EC D P C G C NT GSY C
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLC 1469
Query: 64 LCEPGFAPTAAGY-CADV--DECAADSMCKGGRCVNSEGSF-------QCVCEAGYRPTA 113
C F +G C D C ++ +G ++ C C G
Sbjct: 1470 SCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGN 1529
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSF--------RCECLPGFTLSNDGRTCLGLKLG 165
C + E + +C G P C+ LPG D G
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQ-PNRITVILEDIDECQELPGLCQGGDCVNTFG---- 1584
Query: 166 WGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICD 225
C+ P + +C DI+EC+ C G+C N Y C+C
Sbjct: 1585 -SFQCECPPGYHLSEHTRICE----------DIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 226 PGY-HPDADGLCRDIDECDMHQSYCAGGQCRNT-AGSFT---CVCPE--GTRHEPELQLC 278
Y + C D+ + + Y G C+N A + T C C G + C
Sbjct: 1634 AEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEAC 1691
Query: 279 R-----DIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECE 333
D G ++ +D G P E+ + C NG CIN G F CEC
Sbjct: 1692 PTPISPDYQILCGNQAPGFL-TDIHTGK-PLDIDECGEIPAICANGICINQIGSFRCECP 1749
Query: 334 LGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXX 393
G+ ++ C D C R Q A + C C+
Sbjct: 1750 AGFNYNSILLACEDV--DECGSRESPCQQNADCINIPGSYRCKCT--------------- 1792
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+G+ G C +EC +C+ G C++T+GSY C C G + T
Sbjct: 1793 -----RGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQT 1843
Score = 75.8 bits (178), Expect = 3e-13
Identities = 48/138 (34%), Positives = 63/138 (45%), Gaps = 9/138 (6%)
Query: 316 CDNG-RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NG RCI G C C G+ + +R D R G C+ +V C+ L+ +
Sbjct: 155 CHNGGRCI---GPNRCACVYGF-MGPQCER--DYRTGPCFGQVGPEGCQHQLTGLVCTKA 208
Query: 375 -CCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVNTDG 432
CC +VG AWG +GF + C+DVDEC LC GG+CVN G
Sbjct: 209 LCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVG 268
Query: 433 SYRCDCPPGLTLDSTGTA 450
S+ C CP G L + A
Sbjct: 269 SFHCRCPVGHRLSDSSAA 286
Score = 70.5 bits (165), Expect = 1e-11
Identities = 79/272 (29%), Positives = 97/272 (35%), Gaps = 45/272 (16%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT 72
N+ G F C PG+ + + C V CR R C G C C C G
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV-VPICR---RACGEGFCSQPN---LCTCADGTLAP 110
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
+ G C+ M GG C + C+C+ GY T D R C N
Sbjct: 111 SCGVSRG-SGCSVSCM-NGGTCRGAS----CLCQKGYTGTVCGQPICD-------RGCHN 157
Query: 133 G-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
G RC G RC C+ GF G C+ G + + PEG
Sbjct: 158 GGRCI---GPNRCACVYGFM---------------GPQCERDYRTGP-CFGQVGPEGCQH 198
Query: 192 DNGGADINE--CTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSY 248
G + C A G CE L P C G+ P+ G C+D+DEC
Sbjct: 199 QLTGLVCTKALCCATVGRAWGLPCE-LCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGL 257
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
C GG C N GSF C CP G R C D
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 61.7 bits (143), Expect = 5e-09
Identities = 23/70 (32%), Positives = 35/70 (50%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C+N G F C C +G+ L ++ C D R G+C+ + G+C R++C
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQC 317
Query: 376 CCSVGLAWGS 385
CC G W +
Sbjct: 318 CCDRGRCWAA 327
Score = 55.6 bits (128), Expect = 3e-07
Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C G+ P GAC DVDEC+ +C+ G C N GSF C C G LS+ C +
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Query: 164 LG 165
G
Sbjct: 292 AG 293
Score = 41.5 bits (93), Expect = 0.006
Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
C DVDEC S C G CVN G+Y C C PG T A
Sbjct: 447 CIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQA 486
Score = 40.3 bits (90), Expect = 0.014
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 5/68 (7%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCR-NTAGSYT- 62
G+C G C N+ G F C C G+ A C D V GRC + AG YT
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDY-RAGACFSVLFGGRCAGDLAGHYTR 314
Query: 63 --CLCEPG 68
C C+ G
Sbjct: 315 RQCCCDRG 322
>AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 308 bits (756), Expect = 3e-83
Identities = 170/465 (36%), Positives = 236/465 (50%), Gaps = 39/465 (8%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C +G C NI G + C C PG+++ C DVDEC + +C GRC NT GS+ C+C
Sbjct: 458 CHHGDCVNIPGTYHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + G C D +ECA +MC G C+N +GSF C+C+ G+ C+D+DEC+
Sbjct: 518 AGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ 577
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG---WGV----SCQACPAQGS 178
+C NG C NT GSFRC+CL G + DGR C+ + +G SC A P G+
Sbjct: 578 TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC-ARPFPGT 636
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
+ C P D+G + C P S E ++ +C G DG RD
Sbjct: 637 VTKSECCCANP--DHGFGE--PCQLCPA---KNSAE-----FQALCSSGLGITTDG--RD 682
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIES 295
I+EC + CA G C N GS+ CVC G + C D+DEC + + + ++
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQN 742
Query: 296 D--YERGDIPPTFP--TRTE--------LASPCDNGRCINTHGGFECECELGYVLDATAQ 343
PP F TE L+SPC +G C N G + C+C G LD +
Sbjct: 743 SPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGT 802
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
CLD+ +G+CW ++ + +CE LR ECC ++G AWGS +GFA+
Sbjct: 803 FCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS-PCERCEIDPACARGFAR 861
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+ G TC DV+EC +C G CVNT GS+RC+CP GL LD++G
Sbjct: 862 MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 263 bits (644), Expect = 1e-69
Identities = 165/493 (33%), Positives = 222/493 (45%), Gaps = 55/493 (11%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+CT+G C+N G F C C G+ ++ C D+DECR +P +C +G C NT GS+ C
Sbjct: 995 GLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 65 CEPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG+ C DVDECA D +C+GG C N++GS++C C G+ TA AC D+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDI 1114
Query: 122 DECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQ 176
DEC +C +G+C N G+F+C C GF + D + C+ + G +
Sbjct: 1115 DECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE 1174
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
GS Y C +G S G AD++EC P C G C N+ G+RC+C G+ D
Sbjct: 1175 GS--YRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1232
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C D+DECD++ C G C NT GSF C C G C D+DEC E H
Sbjct: 1233 MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC--EVGGHN 1290
Query: 293 IESDYERGDIPPTFPTR---------------TELASP---CD-NGRCINTHGGFECECE 333
+S +IP +F R E S C G C+N G + C C
Sbjct: 1291 CDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 334 LGYVLDA----TAQRCLDN----RRGSCWRRVVDGQCEAAA---PELLLR-----QECCC 377
G+ D C +N G C +CE P R EC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ 1410
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYR 435
A+GS G+ +LD G C D++ECA C G C+NT GSY
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGY-ELDRGGGNCTDINECADPVN-CINGVCINTPGSYL 1468
Query: 436 CDCPPGLTLDSTG 448
C CP L+ +G
Sbjct: 1469 CSCPQDFELNPSG 1481
Score = 251 bits (614), Expect = 4e-66
Identities = 154/458 (33%), Positives = 196/458 (42%), Gaps = 60/458 (13%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RG-RCRNTAGSYTCLCEPGF 69
C N +G + C C GY +GA+CRDVDEC D + C RG C+N G++ C+C PG
Sbjct: 2181 CHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGM 2240
Query: 70 APTAAGY--CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
P C D +EC A +C GRCVN+ GSF+C C+ G++P+ T C D+
Sbjct: 2241 RPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDI----- 2295
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
R G C C L + + C G GWG C+ CP G+ Y LC
Sbjct: 2296 ----RQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLC 2351
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
P G G D++EC + C HG C N +RC C GY PDA C D+DEC
Sbjct: 2352 PHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQ 2411
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI-- 302
C C+NT GSF C CP G E + + C+D+DEC G
Sbjct: 2412 VPKPCT-FLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTC 2470
Query: 303 --PPTFPTRTELA----------SPCD-NGRCINTHGGFECECELGYVLDATAQRCLDNR 349
PP F + PC +G C NT G F CEC G+ L ++ C D
Sbjct: 2471 RCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED-- 2528
Query: 350 RGSCWRRVVDG--QCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA 407
C DG +C+ L C C G S A
Sbjct: 2529 VNEC-----DGPHRCQHGCQNQLGGYRCSCPQGFTQHS-------------------QWA 2564
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
C D +ECALS C +C NT G +RC CP G D
Sbjct: 2565 QCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFD 2602
Score = 236 bits (578), Expect = 1e-61
Identities = 158/481 (32%), Positives = 217/481 (45%), Gaps = 47/481 (9%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G C G C+N++G F CIC PG++ S+ C D+DEC + P +C G C N+ GS+ CL
Sbjct: 1938 GTCLPGTCQNLEGSFRCICPPGFQVQSDH--CIDIDECSEEPNLCLFGTCTNSPGSFQCL 1995
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCV--NSEGSFQCVCEAGYRPTATRGACVDV 121
C PGF + G+ C D + + + G+C + + + C RP G
Sbjct: 1996 CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWG----- 2050
Query: 122 DECEEQRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D CE +C F +PG S + G + GS
Sbjct: 2051 DPCE---LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGS- 2106
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ CP G S D G D +EC+ V C G+C N+ G+ C C G+ P C
Sbjct: 2107 -FRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCTNVIGGFECACADGFEPGLMMTC 2164
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETETHY--I 293
DIDEC ++ CA +C NT GS+ C CP G + +CRD+DEC +G+ + H +
Sbjct: 2165 EDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM 2223
Query: 294 ESDYERGDI----PP---TFPTRTE--------LASP--CDNGRCINTHGGFECECELGY 336
E G PP P E A P C NGRC+NT G F C+C+ G+
Sbjct: 2224 ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGF 2283
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEA--AAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
T C D R+G C+ V+ C + ++ E + R ECCC G WG
Sbjct: 2284 QPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPG 2343
Query: 395 XXXXKGFAKL-DGATC--RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
+ G T RDVDEC + A LCA G C+N+ GS+RC C G T D+T T
Sbjct: 2344 TSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Query: 452 L 452
L
Sbjct: 2404 L 2404
Score = 235 bits (574), Expect = 3e-61
Identities = 148/442 (33%), Positives = 197/442 (44%), Gaps = 46/442 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDEC 83
PG+ + D+DEC + P +C G C N GS+ C C GF + C DVDEC
Sbjct: 1708 PGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC 1767
Query: 84 AA-DSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPG 140
+ +S C + C+N GS++C C GY+ + GACV +EC E VC +G C +T G
Sbjct: 1768 GSRESPCQQNADCINIPGSYRCKCTRGYK-LSPGGACVGRNECREIPNVCSHGDCMDTEG 1826
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG-SELYAVLCPEGPSKDNGG--AD 197
S+ C C GF S D C+ + C + Y LC G + G D
Sbjct: 1827 SYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVD 1886
Query: 198 INECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCR 255
+ECT + G C G C N + C+C G+ ADG C D +EC C G C+
Sbjct: 1887 FDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N GSF C+CP G + + C DIDEC E
Sbjct: 1947 NLEGSFRCICPPG--FQVQSDHCIDIDECSEEPNL------------------------- 1979
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C N+ G F+C C G+VL RC D R+ C+ R G+C + C
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 376 CCS--VGLAWGSXXXXXXXXXXXXXK-----GFAKLDGA--TCRDVDECALSAELCAGGT 426
CCS G WG + G + G + DV+ECA + +C G
Sbjct: 2040 CCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGV 2099
Query: 427 CVNTDGSYRCDCPPGLTLDSTG 448
CVNTDGS+RC+CP G +LD TG
Sbjct: 2100 CVNTDGSFRCECPFGYSLDFTG 2121
Score = 225 bits (550), Expect = 3e-58
Identities = 154/461 (33%), Positives = 202/461 (43%), Gaps = 58/461 (12%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG+C+N+ G + C+C GYE+G+ G C DVDEC N +C G C+N+ GSY+C C
Sbjct: 692 VCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSC 751
Query: 66 EPGF-APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
PGF C DVDEC + S C G C N GS+ C C G R + C+D
Sbjct: 752 PPGFHFWQDTEICKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD---- 806
Query: 125 EEQRVCRNGRCHNTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
G C RCE L G +L ++ C L WG C+ C +
Sbjct: 807 -----STKGTCWLKIQESRCEVNLQGASLRSE--CCATLGAAWGSPCERCEIDPA----- 854
Query: 184 LCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDI- 239
C G ++ G D+NEC + PG CP+G C N +RC C G DA G LC D+
Sbjct: 855 -CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVR 913
Query: 240 -DECDMH--QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET----ETHY 292
+ C + + C G C C G E + C D + E + +
Sbjct: 914 LEPCFLRWDEDEC-GVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGF 972
Query: 293 IESDYERGDIPPTFPTRTE---LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
D+ G P + E C +G C NT G F C C G+ LDA + C D
Sbjct: 973 ASRDFLSG--RPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD-- 1028
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
+D +C +P+L C G + GF + C
Sbjct: 1029 --------ID-ECR-ISPDL-------CGQGTCVNTPGSFECECFPGYESGFMLM--KNC 1069
Query: 410 RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
DVDECA LC GGTC NTDGSY+C CPPG L + GTA
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTA 1110
Score = 224 bits (547), Expect = 6e-58
Identities = 150/457 (32%), Positives = 195/457 (42%), Gaps = 72/457 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C N G F C+C+ G+E ++G C D +EC C G C+N GS+ C
Sbjct: 1895 GQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRC 1954
Query: 64 LCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PGF + +C D+DEC+ + ++C G C NS GSFQC+C G+ + C D
Sbjct: 1955 ICPPGF-QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDT- 2012
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSEL 180
R C + +C F + R C + GWG C+ CP +GS
Sbjct: 2013 --------RQSFCFTRFEAGKCSVPKAFNTTKT-RCCCSKRPGEGWGDPCELCPQEGSAA 2063
Query: 181 YAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
+ LCP G P D+ D+NEC PG C +G C N + +RC C GY D G+
Sbjct: 2064 FQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGIN 2123
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL-CRDIDECEGETETHYIE 294
C D DEC + C G C N G F C C +G EP L + C DIDEC
Sbjct: 2124 CVDTDECSVGHP-CGQGTCTNVIGGFECACADG--FEPGLMMTCEDIDEC---------- 2170
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCW 354
+ P A C N T G + C C GY L C D C
Sbjct: 2171 ------SLNPLL-----CAFRCHN-----TEGSYLCTCPAGYTLREDGAMCRD--VDEC- 2211
Query: 355 RRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA--TCRDV 412
DGQ + A + EC +G G L G+ C D
Sbjct: 2212 ---ADGQQDCHARGM----ECKNLIG-----------TFACVCPPGMRPLPGSGEGCTDD 2253
Query: 413 DECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+EC +LC G CVNT GS+RCDC G T T
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLT 2290
Score = 217 bits (529), Expect = 9e-56
Identities = 143/421 (33%), Positives = 184/421 (43%), Gaps = 61/421 (14%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDEC-AADSMCKGGRC 94
+DV+EC+ P +C G CRNT GS+ C C GFA A C D+DEC + +C G C
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ GSF+C C GY C+DVDEC + +CR G C NT GS++C+C PG L
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 153 SNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG-ADINECTAVPG 206
+ G C + L G+ + C G + D G DINEC G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 207 ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
C C N E YRC C GY DG C D+DEC+ + C G C N G C+C
Sbjct: 1165 GC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLC 1223
Query: 266 PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTH 325
+G P+++ C D+DEC D+ P C +G C NT
Sbjct: 1224 YDGFMATPDMRTCVDVDEC----------------DLNPHI---------CLHGDCENTK 1258
Query: 326 GGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
G F C C+LGY++ A C D C V C++ A L + C W
Sbjct: 1259 GSFVCHCQLGYMVRKGATGCSD--VDEC--EVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTL 444
DG C D+DEC C+ G C+N GSYRC C G
Sbjct: 1315 -------------------DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 445 D 445
D
Sbjct: 1356 D 1356
Score = 210 bits (513), Expect = 8e-54
Identities = 102/272 (37%), Positives = 143/272 (52%), Gaps = 12/272 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCL 64
+C NGIC N G F C C G+ S C DVDEC C++ C N GSY C
Sbjct: 1731 ICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 65 CEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G+ + G C +EC ++C G C+++EGS+ C+C G++ +A + C+D+DE
Sbjct: 1791 CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDE 1850
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP----AQGSE 179
C+ Q C NG C N GS+ C C PGF ++++G C+ + Q C +
Sbjct: 1851 CDRQ-PCGNGTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAG 1908
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ LC +G G D NEC ++ G C G+C+NLE +RCIC PG+ +D C
Sbjct: 1909 SFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDH-C 1967
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
DIDEC + C G C N+ GSF C+CP G
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPG 1999
Score = 206 bits (503), Expect = 1e-52
Identities = 161/471 (34%), Positives = 197/471 (41%), Gaps = 70/471 (14%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C G C N+ GGFEC C G+E G C D+DEC NP +C RC NT GSY C
Sbjct: 2133 GHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDIDECSLNPLLCAF-RCHNTEGSYLC 2190
Query: 64 LCEPGFAPTAAG-YCADVDECA---ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG-AC 118
C G+ G C DVDECA D +G C N G+F CVC G RP G C
Sbjct: 2191 TCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Query: 119 VDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
D +EC Q +C NGRC NT GSFRC+C GF S C ++ G C A
Sbjct: 2251 TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG---PCFA----- 2302
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLE-PG---YRCICDPGYHPDAD 233
E+ +C S + EC G CE PG YR +C G A+
Sbjct: 2303 -EVLQTMC-RSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE 2360
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G RD+DEC M CA G+C N+ GSF C C G + C D+DEC
Sbjct: 2361 G--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDEC--------- 2409
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD-----N 348
+++ PC C NT G F C C GY+L+ + C D +
Sbjct: 2410 ----------------SQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS 2452
Query: 349 RRGSCWRRVVD--GQCEAAAPELLLRQ--------ECCCSVGL--AWGSXXXXXXXXXXX 396
R+ +C V+ G P + EC G A G
Sbjct: 2453 RQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCE 2512
Query: 397 XXKGFAKLD-GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+GF + G C DV+EC C G C N G YRC CP G T S
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHS 2561
Score = 201 bits (490), Expect = 5e-51
Identities = 150/455 (32%), Positives = 193/455 (42%), Gaps = 42/455 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ GG C+C G+ + + C DVDEC NP +C G C NT GS+
Sbjct: 1203 NPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFV 1262
Query: 63 CLCEPGF-APTAAGYCADVDEC-AADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C+ G+ A C+DVDEC C C+N GSF C C G+ C
Sbjct: 1263 CHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECH 1320
Query: 120 DVDEC--EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC-----LGLKLGWGVSCQA 172
D+DEC +E R G C N PGS+RC C GF + DG C + + Q
Sbjct: 1321 DLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQC 1378
Query: 173 CPAQGSELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A G Y C G P++D+ D++EC A C GSCENL +RCIC+ GY
Sbjct: 1379 LNAPGG--YRCECEMGFDPTEDHRACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYE 1435
Query: 230 PD-ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET 288
D G C DI+EC C G C NT GS+ C CP+ P C D
Sbjct: 1436 LDRGGGNCTDINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFL 1494
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYVLDATAQRCL- 346
ETH +RGD E+ C + G + CEL + + T R L
Sbjct: 1495 ETH------DRGD--SGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLC 1546
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
G R+ ++ EC GL G L
Sbjct: 1547 PGGEGFQPNRIT-----VILEDI---DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 407 AT--CRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
T C D+DEC+ + +C GTC NT G+Y C CP
Sbjct: 1599 HTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 196 bits (478), Expect = 1e-49
Identities = 147/440 (33%), Positives = 184/440 (41%), Gaps = 47/440 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECA 84
PG + L + +D CR +C GRC T SY C C G+ G C DVDEC
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT 454
Query: 85 ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFR 143
+ S C G CVN G++ C C G++ T TR ACVDVDEC +C GRC NT GSF+
Sbjct: 455 S-SPCHHGDCVNIPGTYHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQ 513
Query: 144 CECLPGFTLSNDGRTCLG-LKLGWGVSC--QACPAQGSELYAVLCPEGPSKDNGG---AD 197
C C GF LS DG+ C+ + C C + ++ LC G GG D
Sbjct: 514 CVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGS-FSCLCKPGFLLAPGGHYCMD 572
Query: 198 INECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-R 255
I+EC PG C +G C N E +RC C G DG +C D G C R
Sbjct: 573 IDEC-QTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCAR 631
Query: 256 NTAGSFT---CVC--PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G+ T C C P+ EP QLC + E + G
Sbjct: 632 PFPGTVTKSECCCANPDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDP 690
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPEL 369
E+ C NG C N G + C C LGY A+ + C D + + D G C+ +
Sbjct: 691 EV---CANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGS- 746
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + D C+DVDEC S C G C N
Sbjct: 747 ---YSCSCPPGFHFWQ-------------------DTEICKDVDECLSSP--CVSGVCRN 782
Query: 430 TDGSYRCDCPPGLTLDSTGT 449
GSY C C PG LD +GT
Sbjct: 783 LAGSYTCKCGPGSRLDPSGT 802
Score = 193 bits (471), Expect = 9e-49
Identities = 109/272 (40%), Positives = 138/272 (50%), Gaps = 14/272 (5%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G C N G F C C+ GY + C D+DEC P+ C C+NT GS+ C C
Sbjct: 2373 LCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSC 2431
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DEC + CVN+ G+F C C G+ T AC D DEC
Sbjct: 2432 PRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGF--TQHHQACFDNDEC 2489
Query: 125 EEQ-RVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQ-ACPAQGSEL 180
Q C +G CHNTPGSFRCEC GFTL + G C + G CQ C Q
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGG- 2548
Query: 181 YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLC 236
Y CP+G ++ + A D NEC P C SC N G+RC+C G+ D A G C
Sbjct: 2549 YRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGC 2608
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
+D+DEC + C+ C NT G F C CP+G
Sbjct: 2609 QDVDECAGRRGPCS-YSCANTPGGFLCGCPQG 2639
Score = 187 bits (456), Expect = 6e-47
Identities = 155/470 (32%), Positives = 194/470 (41%), Gaps = 88/470 (18%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C NG C+N G + C C PG+ + +C+DVDEC +P C G CRN AGSYT
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYT 788
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRC-VNSEGS---FQCVCEAG--------- 108
C C PG +G +C D + + RC VN +G+ +C G
Sbjct: 789 CKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCER 848
Query: 109 --YRPTATRG-------ACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
P RG C DV+ECE VC NGRC NT GSFRCEC G L GR
Sbjct: 849 CEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRL 908
Query: 159 CLGLKLGWGVSCQACPAQGSE-LYAVLCPEGPSKDNGGADINECTAVP-GACPHGSCENL 216
C+ ++L + C + E V P D I V ACP E+L
Sbjct: 909 CVDVRL------EPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACP--DPESL 960
Query: 217 EPGYRCICDPGYHP----DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE 272
E C G+ +D++EC + C G CRNT GSF C C G +
Sbjct: 961 EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALD 1020
Query: 273 PELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECEC 332
+ + C DIDEC I P C G C+NT G FECEC
Sbjct: 1021 AQERNCTDIDECR----------------ISPDL---------CGQGTCVNTPGSFECEC 1055
Query: 333 ELGYVLD-ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
GY + C+D VD E A LL R C + GS
Sbjct: 1056 FPGYESGFMLMKNCMD----------VD---ECARDPLLCRGGTCTNTD---GSYKCQCP 1099
Query: 392 XXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
KG A C D+DEC+LS LC G CVN G+++C C G
Sbjct: 1100 PGHELTAKGTA------CEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAG 1143
Score = 176 bits (428), Expect = 2e-43
Identities = 115/324 (35%), Positives = 143/324 (44%), Gaps = 42/324 (12%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADV 80
+C G +EG RDVDECR +C G C N+ GS+ C C+ G+ P A A C D+
Sbjct: 2350 LCPHGSGYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC+ C N++GSF C C GY C D+DEC ++ C NT G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVG 2466
Query: 141 SFRCECLPGFTLSN----DGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG---PSKDN 193
+F C C PGFT + D C G GS + C +G S +
Sbjct: 2467 AFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGS--FRCECHQGFTLVSSGH 2524
Query: 194 GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSYCAGG 252
G D+NEC P C HG C+N GYRC C G+ + C D +EC + C
Sbjct: 2525 GCEDVNECDG-PHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSA 2582
Query: 253 QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTEL 312
CRNT G F CVCP G + L C+D+DEC G RG
Sbjct: 2583 SCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG-----------RRG------------ 2619
Query: 313 ASPCDNGRCINTHGGFECECELGY 336
PC C NT GGF C C GY
Sbjct: 2620 --PCSYS-CANTPGGFLCGCPQGY 2640
Score = 174 bits (424), Expect = 5e-43
Identities = 131/455 (28%), Positives = 188/455 (41%), Gaps = 75/455 (16%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
G++ + D+DEC++ P +C+ G C NT GS+ C C PG+ + C D+DEC+
Sbjct: 1551 GFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECS 1610
Query: 85 A-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC---RNGRCHNTPG 140
S+C G C N+ G++ CVC A Y C+D+ + VC NG C N
Sbjct: 1611 THSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM----RKSVCFRHYNGTCQNELA 1666
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLG--WGVSCQACPAQGSELYAVLC-PEGPS-----KD 192
F ++ C +G W C+ACP S Y +LC + P
Sbjct: 1667 ---------FNVTRK-MCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHT 1716
Query: 193 NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYC-A 250
DI+EC +P C +G C N +RC C G++ ++ L C D+DEC +S C
Sbjct: 1717 GKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ 1776
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
C N GS+ C C G + P C G E
Sbjct: 1777 NADCINIPGSYRCKCTRGYKLSPG-------GACVGRNECR------------------- 1810
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRR----GSCWRRVVDGQC 362
E+ + C +G C++T G + C C G+ A C+D +R+ G+C + C
Sbjct: 1811 EIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNC 1870
Query: 363 EAAAPELLLR--------QECCCSVG--LAWGSXXXXXXXXXXXXXKGF-AKLDGATCRD 411
P ++ EC VG +G GF DG C D
Sbjct: 1871 -LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD 1929
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+EC A C GTC N +GS+RC CPPG + S
Sbjct: 1930 TNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQS 1964
Score = 174 bits (424), Expect = 5e-43
Identities = 126/387 (32%), Positives = 161/387 (41%), Gaps = 66/387 (17%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-----------CR----DNPRVCR 50
+C NG C N G F C C G++ C D+ + CR + V R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 51 RGRCRNTAGSYTCLCE----PG------FAPTAAGYCA---DVDEC-AADSMCKGGRCVN 96
C + CE PG P +GY A DVDEC +C G C+N
Sbjct: 2322 AECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECIN 2381
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S GSF+C C+AGY P AT C+D+DEC + C NT GSF C C G+ L DG
Sbjct: 2382 SLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Query: 157 RTCLGLK--LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGAC-PHGS 212
RTC L +CQ + CP G ++ + D +EC+A PG C HG
Sbjct: 2442 RTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGH 2501
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
C N +RC C G+ + G C D++ECD C G C+N G + C CP+G
Sbjct: 2502 CHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQ 2559
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ C D +EC PPT C + C NT GGF C
Sbjct: 2560 HSQWAQCVDENECALS---------------PPT----------CGSASCRNTLGGFRCV 2594
Query: 332 CELGYVLDATAQRCLD-----NRRGSC 353
C G+ D C D RRG C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPC 2621
Score = 171 bits (416), Expect = 4e-42
Identities = 131/471 (27%), Positives = 182/471 (38%), Gaps = 63/471 (13%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C G C N G F+C C PGY +C D+DEC + +C G C NT G+YTC+
Sbjct: 1572 GLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCV 1631
Query: 65 CEPGFAPTAAG-YCADVDECAA----DSMCKGGRCVNSEGSFQCVCEAGYRPTATR--GA 117
C + G C D+ + + C+ N C C R A
Sbjct: 1632 CPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRK-MCCCSYNIGQAWNRPCEA 1690
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
C + Q +C N PG F + G L D + G+ G
Sbjct: 1691 CPTPISPDYQILCGN----QAPG-FLTDIHTGKPLDIDECGEIPAICANGICINQI---G 1742
Query: 178 SELYAVLCPEGPSKDN---GGADINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDAD 233
S + CP G + ++ D++EC + C + C N+ YRC C GY
Sbjct: 1743 S--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPG 1800
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE----GETE 289
G C +EC + C+ G C +T GS+ C+C G + + LC DIDEC+ G
Sbjct: 1801 GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT 1860
Query: 290 THYIESDY-----------ERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
I Y GD T + C G C+NT G F C C+ G+ L
Sbjct: 1861 CKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFEL 1920
Query: 339 DATAQRCLD-NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
A + C+D N S + G C+ C C G
Sbjct: 1921 TADGKNCVDTNECLSLAGTCLPGTCQNLEGSF----RCICPPGF---------------- 1960
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
++ C D+DEC+ LC GTC N+ GS++C CPPG L G
Sbjct: 1961 -----QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2006
Score = 161 bits (392), Expect = 3e-39
Identities = 143/482 (29%), Positives = 185/482 (38%), Gaps = 85/482 (17%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G+CTNG+C N DG F C C GY G C D DEC C +G C N G +
Sbjct: 2091 NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNVIGGFE 2149
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF P C D+DEC+ + + RC N+EGS+ C C AGY C DVD
Sbjct: 2150 CACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVD 2209
Query: 123 ECEE-QRVC--RNGRCHNTPGSFRCECLPGF-TLSNDGRTCLGLKLGWGVSCQACPAQGS 178
EC + Q+ C R C N G+F C C PG L G C C AQ
Sbjct: 2210 ECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC--------TDDNECHAQPD 2261
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
LC G + G+ +C P C ++ G P + +CR
Sbjct: 2262 -----LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG------PCFAEVLQTMCR 2310
Query: 238 DI---DECDMHQSYCAGG------QCR----NTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
+ E C GG +C ++ +CP G+ + E RD+DEC
Sbjct: 2311 SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE---GRDVDEC 2367
Query: 285 --------EGE--TETHYIESDYERGDIPPTFPTR-------TELASPCDNGRCINTHGG 327
GE + G P T +++ PC C NT G
Sbjct: 2368 RMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGS 2426
Query: 328 FECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
F C C GY+L+ + C D C R C+ + C C
Sbjct: 2427 FLCSCPRGYLLEEDGRTCKD--LDECTSR--QHNCQFLCVNTVGAFTCRCP--------- 2473
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDS 446
GF + A C D DEC+ C A G C NT GS+RC+C G TL S
Sbjct: 2474 -----------PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 447 TG 448
+G
Sbjct: 2522 SG 2523
Score = 155 bits (375), Expect = 4e-37
Identities = 138/468 (29%), Positives = 183/468 (39%), Gaps = 91/468 (19%)
Query: 12 CKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
CKN+ G F C+C PG G C D +EC P +C GRC NTAGS+ C C+ GF
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Query: 71 PTAA-GYCADVDE--CAADSMCKGGRCVNSEGSF----QCVCEAG--------------- 108
P+ C D+ + C A+ + R ++S +C C G
Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 109 --YRPTATRGACV-----DVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
YR G+ DVDEC +C +G C N+ GSFRC C G+T TCL
Sbjct: 2345 SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCL 2404
Query: 161 GLKLGWGVS--CQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ V C + CP G + G D++ECT+ C C N
Sbjct: 2405 DMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVN 2463
Query: 216 LEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPE 274
+ C C PG+ C D DEC C A G C NT GSF C C +G
Sbjct: 2464 TVGAFTCRCPPGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSS 2522
Query: 275 LQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECEL 334
C D++EC+G P R C +G C N GG+ C C
Sbjct: 2523 GHGCEDVNECDG--------------------PHR------CQHG-CQNQLGGYRCSCPQ 2555
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXX 393
G+ + +C+D C + C +A+ L C C G +
Sbjct: 2556 GFTQHSQWAQCVDENE--C--ALSPPTCGSASCRNTLGGFRCVCPSGFDFDQA------- 2604
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
L G C+DVDECA C+ +C NT G + C CP G
Sbjct: 2605 ----------LGG--CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQG 2639
Score = 150 bits (363), Expect = 1e-35
Identities = 94/281 (33%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
MC NG+C N DG F C+CKPG+ G C D+DEC+ P +C G C NT GS+ C C
Sbjct: 540 MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQC 598
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD-E 123
G A G C D S C G +GS C + T T+ C + +
Sbjct: 599 LGGLAVGTDGRVCVDTH---VRSTCYG---AIEKGS----CARPFPGTVTKSECCCANPD 648
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
C+ N+ F+ C G ++ DGR L V Y
Sbjct: 649 HGFGEPCQLCPAKNS-AEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRC 707
Query: 184 LCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDI 239
+C G G D++EC C +G C+N Y C C PG+H D +C+D+
Sbjct: 708 VCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDV 767
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
DEC S C G CRN AGS+TC C G+R +P C D
Sbjct: 768 DEC--LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD 806
Score = 145 bits (351), Expect = 3e-34
Identities = 82/235 (34%), Positives = 111/235 (47%), Gaps = 14/235 (5%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+CKN G F C C GY +G C+D+DEC C+ C NT G++TC C PGF
Sbjct: 2419 LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFT 2477
Query: 71 PTAAGYCADVDECAADSMCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
C D DEC+A G G C N+ GSF+C C G+ ++ C DV+EC+
Sbjct: 2478 QHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPH 2536
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL----YAVL 184
C++G C N G +RC C GFT + C+ + +S C + + +
Sbjct: 2537 RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVD-ENECALSPPTCGSASCRNTLGGFRCV 2594
Query: 185 CPEGPSKDN--GGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
CP G D GG D++EC G C + SC N G+ C C GY G C
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHC 2648
Score = 123 bits (296), Expect = 1e-27
Identities = 69/186 (37%), Positives = 88/186 (47%), Gaps = 7/186 (3%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C +G C N G F C C G+ S G C DV+EC D P C+ G C+N G Y C
Sbjct: 2494 GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHG-CQNQLGGYRC 2551
Query: 64 LCEPGFAPTAA-GYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C GF + C D +ECA + C C N+ G F+CVC +G+ G C DV
Sbjct: 2552 SCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
DEC +R + C NTPG F C C G+ + G G LG+ Q P + L
Sbjct: 2612 DECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSG--LGFSPGPQDTPDKEELLS 2669
Query: 182 AVLCPE 187
+ C E
Sbjct: 2670 SEACYE 2675
Score = 113 bits (273), Expect = 9e-25
Identities = 119/476 (25%), Positives = 167/476 (35%), Gaps = 73/476 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C+N+ G F CIC GYE G C D++EC D P C G C NT GSY C
Sbjct: 1411 GNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLC 1469
Query: 64 LCEPGFAPTAAGY-CADV--DECAADSMCKGGRCVNSEGSF-------QCVCEAGYRPTA 113
C F +G C D C ++ +G ++ C C G
Sbjct: 1470 SCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGN 1529
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSF--------RCECLPGFTLSNDGRTCLGLKLG 165
C + E + +C G P C+ LPG D G
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQ-PNRITVILEDIDECQELPGLCQGGDCVNTFG---- 1584
Query: 166 WGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICD 225
C+ P + +C DI+EC+ C G+C N Y C+C
Sbjct: 1585 -SFQCECPPGYHLSEHTRICE----------DIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 226 PGY-HPDADGLCRDIDECDMHQSYCAGGQCRNT-AGSFT---CVCPE--GTRHEPELQLC 278
Y + C D+ + + Y G C+N A + T C C G + C
Sbjct: 1634 AEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEAC 1691
Query: 279 R-----DIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECE 333
D G ++ +D G P E+ + C NG CIN G F CEC
Sbjct: 1692 PTPISPDYQILCGNQAPGFL-TDIHTGK-PLDIDECGEIPAICANGICINQIGSFRCECP 1749
Query: 334 LGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXX 393
G+ ++ C D C R Q A + C C+
Sbjct: 1750 AGFNYNSILLACEDV--DECGSRESPCQQNADCINIPGSYRCKCT--------------- 1792
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+G+ G C +EC +C+ G C++T+GSY C C G + T
Sbjct: 1793 -----RGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQT 1843
Score = 75.8 bits (178), Expect = 3e-13
Identities = 48/138 (34%), Positives = 63/138 (45%), Gaps = 9/138 (6%)
Query: 316 CDNG-RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NG RCI G C C G+ + +R D R G C+ +V C+ L+ +
Sbjct: 155 CHNGGRCI---GPNRCACVYGF-MGPQCER--DYRTGPCFGQVGPEGCQHQLTGLVCTKA 208
Query: 375 -CCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVNTDG 432
CC +VG AWG +GF + C+DVDEC LC GG+CVN G
Sbjct: 209 LCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVG 268
Query: 433 SYRCDCPPGLTLDSTGTA 450
S+ C CP G L + A
Sbjct: 269 SFHCRCPVGHRLSDSSAA 286
Score = 70.5 bits (165), Expect = 1e-11
Identities = 79/272 (29%), Positives = 97/272 (35%), Gaps = 45/272 (16%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT 72
N+ G F C PG+ + + C V CR R C G C C C G
Sbjct: 58 NVCGSRFHAYCCPGWRTFPGRSQCV-VPICR---RACGEGFCSQPN---LCTCADGTLAP 110
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
+ G C+ M GG C + C+C+ GY T D R C N
Sbjct: 111 SCGVSRG-SGCSVSCM-NGGTCRGAS----CLCQKGYTGTVCGQPICD-------RGCHN 157
Query: 133 G-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
G RC G RC C+ GF G C+ G + + PEG
Sbjct: 158 GGRCI---GPNRCACVYGFM---------------GPQCERDYRTGP-CFGQVGPEGCQH 198
Query: 192 DNGGADINE--CTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSY 248
G + C A G CE L P C G+ P+ G C+D+DEC
Sbjct: 199 QLTGLVCTKALCCATVGRAWGLPCE-LCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGL 257
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
C GG C N GSF C CP G R C D
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 61.7 bits (143), Expect = 5e-09
Identities = 23/70 (32%), Positives = 35/70 (50%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C+N G F C C +G+ L ++ C D R G+C+ + G+C R++C
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQC 317
Query: 376 CCSVGLAWGS 385
CC G W +
Sbjct: 318 CCDRGRCWAA 327
Score = 55.6 bits (128), Expect = 3e-07
Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C G+ P GAC DVDEC+ +C+ G C N GSF C C G LS+ C +
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Query: 164 LG 165
G
Sbjct: 292 AG 293
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
C DVDEC S C G CVN G+Y C C PG T A
Sbjct: 447 CIDVDECTSSP--CHHGDCVNIPGTYHCQCYPGFQATPTRQA 486
Score = 40.3 bits (90), Expect = 0.014
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 5/68 (7%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCR-NTAGSYT- 62
G+C G C N+ G F C C G+ A C D V GRC + AG YT
Sbjct: 256 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDY-RAGACFSVLFGGRCAGDLAGHYTR 314
Query: 63 --CLCEPG 68
C C+ G
Sbjct: 315 RQCCCDRG 322
>AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.
Length = 2816
Score = 308 bits (756), Expect = 3e-83
Identities = 170/465 (36%), Positives = 236/465 (50%), Gaps = 39/465 (8%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C +G C NI G + C C PG+++ C DVDEC + +C GRC NT GS+ C+C
Sbjct: 465 CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 524
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + G C D +ECA +MC G C+N +GSF C+C+ G+ C+D+DEC+
Sbjct: 525 AGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ 584
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG---WGV----SCQACPAQGS 178
+C NG C NT GSFRC+CL G + DGR C+ + +G SC A P G+
Sbjct: 585 TPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSC-ARPFPGT 643
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
+ C P D+G + C P S E ++ +C G DG RD
Sbjct: 644 VTKSECCCANP--DHGFGE--PCQLCPA---KNSAE-----FQALCSSGLGITTDG--RD 689
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIES 295
I+EC + CA G C N GS+ CVC G + C D+DEC + + + ++
Sbjct: 690 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQN 749
Query: 296 D--YERGDIPPTFP--TRTE--------LASPCDNGRCINTHGGFECECELGYVLDATAQ 343
PP F TE L+SPC +G C N G + C+C G LD +
Sbjct: 750 SPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGT 809
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
CLD+ +G+CW ++ + +CE LR ECC ++G AWGS +GFA+
Sbjct: 810 FCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS-PCERCEIDPACARGFAR 868
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+ G TC DV+EC +C G CVNT GS+RC+CP GL LD++G
Sbjct: 869 MTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASG 913
Score = 262 bits (643), Expect = 1e-69
Identities = 165/493 (33%), Positives = 222/493 (45%), Gaps = 55/493 (11%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+CT+G C+N G F C C G+ ++ C D+DECR +P +C +G C NT GS+ C
Sbjct: 1002 GLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1061
Query: 65 CEPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG+ C DVDECA D +C+GG C N++GS++C C G+ TA AC D+
Sbjct: 1062 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDI 1121
Query: 122 DECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQ 176
DEC +C +G+C N G+F+C C GF + D + C+ + G +
Sbjct: 1122 DECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE 1181
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
GS Y C +G S G AD++EC P C G C N+ G+RC+C G+ D
Sbjct: 1182 GS--YRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPD 1239
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C D+DECD++ C G C NT GSF C C G C D+DEC E H
Sbjct: 1240 MRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC--EVGGHN 1297
Query: 293 IESDYERGDIPPTFPTR---------------TELASP---CD-NGRCINTHGGFECECE 333
+S +IP +F R E S C G C+N G + C C
Sbjct: 1298 CDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCR 1357
Query: 334 LGYVLDA----TAQRCLDN----RRGSCWRRVVDGQCEAAA---PELLLR-----QECCC 377
G+ D C +N G C +CE P R EC
Sbjct: 1358 QGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ 1417
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYR 435
A+GS G+ +LD G C D++ECA C G C+NT GSY
Sbjct: 1418 GNLCAFGSCENLPGMFRCICNGGY-ELDRGGGNCTDINECADPVN-CINGVCINTPGSYL 1475
Query: 436 CDCPPGLTLDSTG 448
C CP L+ +G
Sbjct: 1476 CSCPQDFELNPSG 1488
Score = 251 bits (614), Expect = 4e-66
Identities = 154/458 (33%), Positives = 196/458 (42%), Gaps = 60/458 (13%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RG-RCRNTAGSYTCLCEPGF 69
C N +G + C C GY +GA+CRDVDEC D + C RG C+N G++ C+C PG
Sbjct: 2188 CHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGM 2247
Query: 70 APTAAGY--CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
P C D +EC A +C GRCVN+ GSF+C C+ G++P+ T C D+
Sbjct: 2248 RPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDI----- 2302
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
R G C C L + + C G GWG C+ CP G+ Y LC
Sbjct: 2303 ----RQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLC 2358
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
P G G D++EC + C HG C N +RC C GY PDA C D+DEC
Sbjct: 2359 PHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQ 2418
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI-- 302
C C+NT GSF C CP G E + + C+D+DEC G
Sbjct: 2419 VPKPCT-FLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTC 2477
Query: 303 --PPTFPTRTELA----------SPCD-NGRCINTHGGFECECELGYVLDATAQRCLDNR 349
PP F + PC +G C NT G F CEC G+ L ++ C D
Sbjct: 2478 RCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED-- 2535
Query: 350 RGSCWRRVVDG--QCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA 407
C DG +C+ L C C G S A
Sbjct: 2536 VNEC-----DGPHRCQHGCQNQLGGYRCSCPQGFTQHS-------------------QWA 2571
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
C D +ECALS C +C NT G +RC CP G D
Sbjct: 2572 QCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFD 2609
Score = 236 bits (578), Expect = 1e-61
Identities = 158/481 (32%), Positives = 217/481 (45%), Gaps = 47/481 (9%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G C G C+N++G F CIC PG++ S+ C D+DEC + P +C G C N+ GS+ CL
Sbjct: 1945 GTCLPGTCQNLEGSFRCICPPGFQVQSDH--CIDIDECSEEPNLCLFGTCTNSPGSFQCL 2002
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCV--NSEGSFQCVCEAGYRPTATRGACVDV 121
C PGF + G+ C D + + + G+C + + + C RP G
Sbjct: 2003 CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWG----- 2057
Query: 122 DECEEQRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D CE +C F +PG S + G + GS
Sbjct: 2058 DPCE---LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGS- 2113
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ CP G S D G D +EC+ V C G+C N+ G+ C C G+ P C
Sbjct: 2114 -FRCECPFGYSLDFTGINCVDTDECS-VGHPCGQGTCTNVIGGFECACADGFEPGLMMTC 2171
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETETHY--I 293
DIDEC ++ CA +C NT GS+ C CP G + +CRD+DEC +G+ + H +
Sbjct: 2172 EDIDECSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGM 2230
Query: 294 ESDYERGDI----PP---TFPTRTE--------LASP--CDNGRCINTHGGFECECELGY 336
E G PP P E A P C NGRC+NT G F C+C+ G+
Sbjct: 2231 ECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGF 2290
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEA--AAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
T C D R+G C+ V+ C + ++ E + R ECCC G WG
Sbjct: 2291 QPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPG 2350
Query: 395 XXXXKGFAKL-DGATC--RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
+ G T RDVDEC + A LCA G C+N+ GS+RC C G T D+T T
Sbjct: 2351 TSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2410
Query: 452 L 452
L
Sbjct: 2411 L 2411
Score = 235 bits (575), Expect = 2e-61
Identities = 148/442 (33%), Positives = 197/442 (44%), Gaps = 46/442 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDEC 83
PG+ + D+DEC + P +C G C N GS+ C C GF + C DVDEC
Sbjct: 1715 PGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC 1774
Query: 84 AA-DSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPG 140
+ +S C + C+N GS++C C GY+ + GACV +EC E VC +G C +T G
Sbjct: 1775 GSRESPCQQNADCINIPGSYRCKCTRGYK-LSPGGACVGQNECREIPNVCSHGDCMDTEG 1833
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG-SELYAVLCPEGPSKDNGG--AD 197
S+ C C GF S D C+ + C + Y LC G + G D
Sbjct: 1834 SYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVD 1893
Query: 198 INECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCR 255
+ECT + G C G C N + C+C G+ ADG C D +EC C G C+
Sbjct: 1894 FDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1953
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N GSF C+CP G + + C DIDEC E
Sbjct: 1954 NLEGSFRCICPPG--FQVQSDHCIDIDECSEEPNL------------------------- 1986
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C N+ G F+C C G+VL RC D R+ C+ R G+C + C
Sbjct: 1987 CLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRC 2046
Query: 376 CCS--VGLAWGSXXXXXXXXXXXXXK-----GFAKLDGA--TCRDVDECALSAELCAGGT 426
CCS G WG + G + G + DV+ECA + +C G
Sbjct: 2047 CCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGV 2106
Query: 427 CVNTDGSYRCDCPPGLTLDSTG 448
CVNTDGS+RC+CP G +LD TG
Sbjct: 2107 CVNTDGSFRCECPFGYSLDFTG 2128
Score = 225 bits (550), Expect = 3e-58
Identities = 154/461 (33%), Positives = 202/461 (43%), Gaps = 58/461 (12%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG+C+N+ G + C+C GYE+G+ G C DVDEC N +C G C+N+ GSY+C C
Sbjct: 699 VCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSC 758
Query: 66 EPGF-APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
PGF C DVDEC + S C G C N GS+ C C G R + C+D
Sbjct: 759 PPGFHFWQDTEICKDVDECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD---- 813
Query: 125 EEQRVCRNGRCHNTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
G C RCE L G +L ++ C L WG C+ C +
Sbjct: 814 -----STKGTCWLKIQESRCEVNLQGASLRSE--CCATLGAAWGSPCERCEIDPA----- 861
Query: 184 LCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDI- 239
C G ++ G D+NEC + PG CP+G C N +RC C G DA G LC D+
Sbjct: 862 -CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVR 920
Query: 240 -DECDMH--QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET----ETHY 292
+ C + + C G C C G E + C D + E + +
Sbjct: 921 LEPCFLRWDEDEC-GVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGF 979
Query: 293 IESDYERGDIPPTFPTRTE---LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
D+ G P + E C +G C NT G F C C G+ LDA + C D
Sbjct: 980 ASRDFLSG--RPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD-- 1035
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
+D +C +P+L C G + GF + C
Sbjct: 1036 --------ID-ECR-ISPDL-------CGQGTCVNTPGSFECECFPGYESGFMLM--KNC 1076
Query: 410 RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
DVDECA LC GGTC NTDGSY+C CPPG L + GTA
Sbjct: 1077 MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTA 1117
Score = 224 bits (547), Expect = 6e-58
Identities = 150/457 (32%), Positives = 195/457 (42%), Gaps = 72/457 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C N G F C+C+ G+E ++G C D +EC C G C+N GS+ C
Sbjct: 1902 GQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRC 1961
Query: 64 LCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PGF + +C D+DEC+ + ++C G C NS GSFQC+C G+ + C D
Sbjct: 1962 ICPPGF-QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDT- 2019
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSEL 180
R C + +C F + R C + GWG C+ CP +GS
Sbjct: 2020 --------RQSFCFTRFEAGKCSVPKAFNTTKT-RCCCSKRPGEGWGDPCELCPQEGSAA 2070
Query: 181 YAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
+ LCP G P D+ D+NEC PG C +G C N + +RC C GY D G+
Sbjct: 2071 FQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGIN 2130
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL-CRDIDECEGETETHYIE 294
C D DEC + C G C N G F C C +G EP L + C DIDEC
Sbjct: 2131 CVDTDECSVGHP-CGQGTCTNVIGGFECACADG--FEPGLMMTCEDIDEC---------- 2177
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCW 354
+ P A C N T G + C C GY L C D C
Sbjct: 2178 ------SLNPLL-----CAFRCHN-----TEGSYLCTCPAGYTLREDGAMCRD--VDEC- 2218
Query: 355 RRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA--TCRDV 412
DGQ + A + EC +G G L G+ C D
Sbjct: 2219 ---ADGQQDCHARGM----ECKNLIG-----------TFACVCPPGMRPLPGSGEGCTDD 2260
Query: 413 DECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+EC +LC G CVNT GS+RCDC G T T
Sbjct: 2261 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLT 2297
Score = 216 bits (528), Expect = 1e-55
Identities = 143/421 (33%), Positives = 184/421 (43%), Gaps = 61/421 (14%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDEC-AADSMCKGGRC 94
+DV+EC+ P +C G CRNT GS+ C C GFA A C D+DEC + +C G C
Sbjct: 992 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1051
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ GSF+C C GY C+DVDEC + +CR G C NT GS++C+C PG L
Sbjct: 1052 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1111
Query: 153 SNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG-ADINECTAVPG 206
+ G C + L G+ + C G + D G DINEC G
Sbjct: 1112 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1171
Query: 207 ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
C C N E YRC C GY DG C D+DEC+ + C G C N G C+C
Sbjct: 1172 GC-DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLC 1230
Query: 266 PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTH 325
+G P+++ C D+DEC D+ P C +G C NT
Sbjct: 1231 YDGFMATPDMRTCVDVDEC----------------DLNPHI---------CLHGDCENTK 1265
Query: 326 GGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
G F C C+LGY++ A C D C V C++ A L + C W
Sbjct: 1266 GSFVCHCQLGYMVRKGATGCSD--VDEC--EVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1321
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTL 444
DG C D+DEC C+ G C+N GSYRC C G
Sbjct: 1322 -------------------DGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1362
Query: 445 D 445
D
Sbjct: 1363 D 1363
Score = 210 bits (514), Expect = 6e-54
Identities = 102/272 (37%), Positives = 143/272 (52%), Gaps = 12/272 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCL 64
+C NGIC N G F C C G+ S C DVDEC C++ C N GSY C
Sbjct: 1738 ICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCK 1797
Query: 65 CEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G+ + G C +EC ++C G C+++EGS+ C+C G++ +A + C+D+DE
Sbjct: 1798 CTRGYKLSPGGACVGQNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDE 1857
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP----AQGSE 179
C+ Q C NG C N GS+ C C PGF ++++G C+ + Q C +
Sbjct: 1858 CDRQ-PCGNGTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAG 1915
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ LC +G G D NEC ++ G C G+C+NLE +RCIC PG+ +D C
Sbjct: 1916 SFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDH-C 1974
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
DIDEC + C G C N+ GSF C+CP G
Sbjct: 1975 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPG 2006
Score = 206 bits (503), Expect = 1e-52
Identities = 161/471 (34%), Positives = 197/471 (41%), Gaps = 70/471 (14%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C G C N+ GGFEC C G+E G C D+DEC NP +C RC NT GSY C
Sbjct: 2140 GHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDIDECSLNPLLCAF-RCHNTEGSYLC 2197
Query: 64 LCEPGFAPTAAG-YCADVDECA---ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG-AC 118
C G+ G C DVDECA D +G C N G+F CVC G RP G C
Sbjct: 2198 TCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2257
Query: 119 VDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
D +EC Q +C NGRC NT GSFRC+C GF S C ++ G C A
Sbjct: 2258 TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG---PCFA----- 2309
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLE-PG---YRCICDPGYHPDAD 233
E+ +C S + EC G CE PG YR +C G A+
Sbjct: 2310 -EVLQTMC-RSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE 2367
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G RD+DEC M CA G+C N+ GSF C C G + C D+DEC
Sbjct: 2368 G--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDEC--------- 2416
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD-----N 348
+++ PC C NT G F C C GY+L+ + C D +
Sbjct: 2417 ----------------SQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS 2459
Query: 349 RRGSCWRRVVD--GQCEAAAPELLLRQ--------ECCCSVGL--AWGSXXXXXXXXXXX 396
R+ +C V+ G P + EC G A G
Sbjct: 2460 RQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCE 2519
Query: 397 XXKGFAKLD-GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+GF + G C DV+EC C G C N G YRC CP G T S
Sbjct: 2520 CHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHS 2568
Score = 200 bits (488), Expect = 8e-51
Identities = 150/455 (32%), Positives = 193/455 (42%), Gaps = 42/455 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ GG C+C G+ + + C DVDEC NP +C G C NT GS+
Sbjct: 1210 NPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFV 1269
Query: 63 CLCEPGF-APTAAGYCADVDEC-AADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C+ G+ A C+DVDEC C C+N GSF C C G+ C
Sbjct: 1270 CHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW--VGDGFECH 1327
Query: 120 DVDEC--EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC-----LGLKLGWGVSCQA 172
D+DEC +E R G C N PGS+RC C GF + DG C + + Q
Sbjct: 1328 DLDECISQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQC 1385
Query: 173 CPAQGSELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A G Y C G P++D+ D++EC A C GSCENL +RCIC+ GY
Sbjct: 1386 LNAPGG--YRCECEMGFDPTEDHRACQDVDEC-AQGNLCAFGSCENLPGMFRCICNGGYE 1442
Query: 230 PD-ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET 288
D G C DI+EC C G C NT GS+ C CP+ P C D
Sbjct: 1443 LDRGGGNCTDINEC-ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFL 1501
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYVLDATAQRCL- 346
ETH +RGD E+ C + G + CEL + + T R L
Sbjct: 1502 ETH------DRGD--SGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLC 1553
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
G R+ ++ EC GL G L
Sbjct: 1554 PGGEGFQPNRIT-----VILEDI---DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSE 1605
Query: 407 AT--CRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
T C D+DEC+ + +C GTC NT G+Y C CP
Sbjct: 1606 HTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCP 1640
Score = 196 bits (477), Expect = 2e-49
Identities = 147/440 (33%), Positives = 184/440 (41%), Gaps = 47/440 (10%)
Query: 25 PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECA 84
PG + L + +D CR +C GRC T SY C C G+ G C DVDEC
Sbjct: 402 PGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT 461
Query: 85 ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFR 143
+ S C G CVN G++ C C G++ T TR ACVDVDEC +C GRC NT GSF+
Sbjct: 462 S-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQ 520
Query: 144 CECLPGFTLSNDGRTCLG-LKLGWGVSC--QACPAQGSELYAVLCPEGPSKDNGG---AD 197
C C GF LS DG+ C+ + C C + ++ LC G GG D
Sbjct: 521 CVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGS-FSCLCKPGFLLAPGGHYCMD 579
Query: 198 INECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-R 255
I+EC PG C +G C N E +RC C G DG +C D G C R
Sbjct: 580 IDEC-QTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCAR 638
Query: 256 NTAGSFT---CVC--PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G+ T C C P+ EP QLC + E + G
Sbjct: 639 PFPGTVTKSECCCANPDHGFGEP-CQLCPAKNSAEFQALCSSGLGITTDGRDINECALDP 697
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPEL 369
E+ C NG C N G + C C LGY A+ + C D + + D G C+ +
Sbjct: 698 EV---CANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGS- 753
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + D C+DVDEC S C G C N
Sbjct: 754 ---YSCSCPPGFHFWQ-------------------DTEICKDVDECLSSP--CVSGVCRN 789
Query: 430 TDGSYRCDCPPGLTLDSTGT 449
GSY C C PG LD +GT
Sbjct: 790 LAGSYTCKCGPGSRLDPSGT 809
Score = 193 bits (471), Expect = 9e-49
Identities = 109/272 (40%), Positives = 138/272 (50%), Gaps = 14/272 (5%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G C N G F C C+ GY + C D+DEC P+ C C+NT GS+ C C
Sbjct: 2380 LCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSC 2438
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DEC + CVN+ G+F C C G+ T AC D DEC
Sbjct: 2439 PRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGF--TQHHQACFDNDEC 2496
Query: 125 EEQ-RVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQ-ACPAQGSEL 180
Q C +G CHNTPGSFRCEC GFTL + G C + G CQ C Q
Sbjct: 2497 SAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGG- 2555
Query: 181 YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLC 236
Y CP+G ++ + A D NEC P C SC N G+RC+C G+ D A G C
Sbjct: 2556 YRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGC 2615
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
+D+DEC + C+ C NT G F C CP+G
Sbjct: 2616 QDVDECAGRRGPCS-YSCANTPGGFLCGCPQG 2646
Score = 187 bits (456), Expect = 6e-47
Identities = 155/470 (32%), Positives = 194/470 (41%), Gaps = 88/470 (18%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C NG C+N G + C C PG+ + +C+DVDEC +P C G CRN AGSYT
Sbjct: 738 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYT 795
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRC-VNSEGS---FQCVCEAG--------- 108
C C PG +G +C D + + RC VN +G+ +C G
Sbjct: 796 CKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCER 855
Query: 109 --YRPTATRG-------ACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
P RG C DV+ECE VC NGRC NT GSFRCEC G L GR
Sbjct: 856 CEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRL 915
Query: 159 CLGLKLGWGVSCQACPAQGSE-LYAVLCPEGPSKDNGGADINECTAVP-GACPHGSCENL 216
C+ ++L + C + E V P D I V ACP E+L
Sbjct: 916 CVDVRL------EPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACP--DPESL 967
Query: 217 EPGYRCICDPGYHP----DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE 272
E C G+ +D++EC + C G CRNT GSF C C G +
Sbjct: 968 EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALD 1027
Query: 273 PELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECEC 332
+ + C DIDEC I P C G C+NT G FECEC
Sbjct: 1028 AQERNCTDIDECR----------------ISPDL---------CGQGTCVNTPGSFECEC 1062
Query: 333 ELGYVLD-ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
GY + C+D VD E A LL R C + GS
Sbjct: 1063 FPGYESGFMLMKNCMD----------VD---ECARDPLLCRGGTCTNTD---GSYKCQCP 1106
Query: 392 XXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
KG A C D+DEC+LS LC G CVN G+++C C G
Sbjct: 1107 PGHELTAKGTA------CEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAG 1150
Score = 176 bits (428), Expect = 2e-43
Identities = 115/324 (35%), Positives = 143/324 (44%), Gaps = 42/324 (12%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADV 80
+C G +EG RDVDECR +C G C N+ GS+ C C+ G+ P A A C D+
Sbjct: 2357 LCPHGSGYTAEG---RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2413
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC+ C N++GSF C C GY C D+DEC ++ C NT G
Sbjct: 2414 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVG 2473
Query: 141 SFRCECLPGFTLSN----DGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG---PSKDN 193
+F C C PGFT + D C G GS + C +G S +
Sbjct: 2474 AFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGS--FRCECHQGFTLVSSGH 2531
Query: 194 GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSYCAGG 252
G D+NEC P C HG C+N GYRC C G+ + C D +EC + C
Sbjct: 2532 GCEDVNECDG-PHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSA 2589
Query: 253 QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTEL 312
CRNT G F CVCP G + L C+D+DEC G RG
Sbjct: 2590 SCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG-----------RRG------------ 2626
Query: 313 ASPCDNGRCINTHGGFECECELGY 336
PC C NT GGF C C GY
Sbjct: 2627 --PCSYS-CANTPGGFLCGCPQGY 2647
Score = 175 bits (425), Expect = 4e-43
Identities = 131/455 (28%), Positives = 189/455 (41%), Gaps = 75/455 (16%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
G++ + D+DEC++ P +C+ G C NT GS+ C C PG+ + C D+DEC+
Sbjct: 1558 GFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECS 1617
Query: 85 ADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC---RNGRCHNTPG 140
S +C G C N+ G++ CVC A Y C+D+ + VC NG C N
Sbjct: 1618 THSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM----RKSVCFRHYNGTCQNELA 1673
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLG--WGVSCQACPAQGSELYAVLC-PEGPS-----KD 192
F ++ C +G W C+ACP S Y +LC + P
Sbjct: 1674 ---------FNVTRK-MCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHT 1723
Query: 193 NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYC-A 250
DI+EC +P C +G C N +RC C G++ ++ L C D+DEC +S C
Sbjct: 1724 GKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQ 1783
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
C N GS+ C C G + P C G+ E
Sbjct: 1784 NADCINIPGSYRCKCTRGYKLSPG-------GACVGQNECR------------------- 1817
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRR----GSCWRRVVDGQC 362
E+ + C +G C++T G + C C G+ A C+D +R+ G+C + C
Sbjct: 1818 EIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNC 1877
Query: 363 EAAAPELLLR--------QECCCSVG--LAWGSXXXXXXXXXXXXXKGF-AKLDGATCRD 411
P ++ EC VG +G GF DG C D
Sbjct: 1878 -LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVD 1936
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+EC A C GTC N +GS+RC CPPG + S
Sbjct: 1937 TNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQS 1971
Score = 174 bits (424), Expect = 5e-43
Identities = 126/387 (32%), Positives = 161/387 (41%), Gaps = 66/387 (17%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-----------CR----DNPRVCR 50
+C NG C N G F C C G++ C D+ + CR + V R
Sbjct: 2269 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2328
Query: 51 RGRCRNTAGSYTCLCE----PG------FAPTAAGYCA---DVDEC-AADSMCKGGRCVN 96
C + CE PG P +GY A DVDEC +C G C+N
Sbjct: 2329 AECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECIN 2388
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S GSF+C C+AGY P AT C+D+DEC + C NT GSF C C G+ L DG
Sbjct: 2389 SLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2448
Query: 157 RTCLGLK--LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGAC-PHGS 212
RTC L +CQ + CP G ++ + D +EC+A PG C HG
Sbjct: 2449 RTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGH 2508
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
C N +RC C G+ + G C D++ECD C G C+N G + C CP+G
Sbjct: 2509 CHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQ 2566
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ C D +EC PPT C + C NT GGF C
Sbjct: 2567 HSQWAQCVDENECALS---------------PPT----------CGSASCRNTLGGFRCV 2601
Query: 332 CELGYVLDATAQRCLD-----NRRGSC 353
C G+ D C D RRG C
Sbjct: 2602 CPSGFDFDQALGGCQDVDECAGRRGPC 2628
Score = 171 bits (415), Expect = 6e-42
Identities = 131/471 (27%), Positives = 182/471 (38%), Gaps = 63/471 (13%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C G C N G F+C C PGY +C D+DEC + +C G C NT G+YTC+
Sbjct: 1579 GLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCV 1638
Query: 65 CEPGFAPTAAG-YCADVDECAA----DSMCKGGRCVNSEGSFQCVCEAGYRPTATR--GA 117
C + G C D+ + + C+ N C C R A
Sbjct: 1639 CPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRK-MCCCSYNIGQAWNRPCEA 1697
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
C + Q +C N PG F + G L D + G+ G
Sbjct: 1698 CPTPISPDYQILCGN----QAPG-FLTDIHTGKPLDIDECGEIPAICANGICINQI---G 1749
Query: 178 SELYAVLCPEGPSKDN---GGADINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDAD 233
S + CP G + ++ D++EC + C + C N+ YRC C GY
Sbjct: 1750 S--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPG 1807
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE----GETE 289
G C +EC + C+ G C +T GS+ C+C G + + LC DIDEC+ G
Sbjct: 1808 GACVGQNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT 1867
Query: 290 THYIESDY-----------ERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
I Y GD T + C G C+NT G F C C+ G+ L
Sbjct: 1868 CKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFEL 1927
Query: 339 DATAQRCLD-NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
A + C+D N S + G C+ C C G
Sbjct: 1928 TADGKNCVDTNECLSLAGTCLPGTCQNLEGSF----RCICPPGF---------------- 1967
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
++ C D+DEC+ LC GTC N+ GS++C CPPG L G
Sbjct: 1968 -----QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNG 2013
Score = 161 bits (392), Expect = 3e-39
Identities = 143/482 (29%), Positives = 185/482 (38%), Gaps = 85/482 (17%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G+CTNG+C N DG F C C GY G C D DEC C +G C N G +
Sbjct: 2098 NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNVIGGFE 2156
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF P C D+DEC+ + + RC N+EGS+ C C AGY C DVD
Sbjct: 2157 CACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVD 2216
Query: 123 ECEE-QRVC--RNGRCHNTPGSFRCECLPGF-TLSNDGRTCLGLKLGWGVSCQACPAQGS 178
EC + Q+ C R C N G+F C C PG L G C C AQ
Sbjct: 2217 ECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC--------TDDNECHAQPD 2268
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
LC G + G+ +C P C ++ G P + +CR
Sbjct: 2269 -----LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG------PCFAEVLQTMCR 2317
Query: 238 DI---DECDMHQSYCAGG------QCR----NTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
+ E C GG +C ++ +CP G+ + E RD+DEC
Sbjct: 2318 SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE---GRDVDEC 2374
Query: 285 --------EGE--TETHYIESDYERGDIPPTFPTR-------TELASPCDNGRCINTHGG 327
GE + G P T +++ PC C NT G
Sbjct: 2375 RMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGS 2433
Query: 328 FECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
F C C GY+L+ + C D C R C+ + C C
Sbjct: 2434 FLCSCPRGYLLEEDGRTCKD--LDECTSR--QHNCQFLCVNTVGAFTCRCP--------- 2480
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDS 446
GF + A C D DEC+ C A G C NT GS+RC+C G TL S
Sbjct: 2481 -----------PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2528
Query: 447 TG 448
+G
Sbjct: 2529 SG 2530
Score = 155 bits (375), Expect = 4e-37
Identities = 138/468 (29%), Positives = 183/468 (39%), Gaps = 91/468 (19%)
Query: 12 CKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
CKN+ G F C+C PG G C D +EC P +C GRC NTAGS+ C C+ GF
Sbjct: 2232 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2291
Query: 71 PTAA-GYCADVDE--CAADSMCKGGRCVNSEGSF----QCVCEAG--------------- 108
P+ C D+ + C A+ + R ++S +C C G
Sbjct: 2292 PSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2351
Query: 109 --YRPTATRGACV-----DVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
YR G+ DVDEC +C +G C N+ GSFRC C G+T TCL
Sbjct: 2352 SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCL 2411
Query: 161 GLKLGWGVS--CQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ V C + CP G + G D++ECT+ C C N
Sbjct: 2412 DMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVN 2470
Query: 216 LEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPE 274
+ C C PG+ C D DEC C A G C NT GSF C C +G
Sbjct: 2471 TVGAFTCRCPPGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSS 2529
Query: 275 LQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECEL 334
C D++EC+G P R C +G C N GG+ C C
Sbjct: 2530 GHGCEDVNECDG--------------------PHR------CQHG-CQNQLGGYRCSCPQ 2562
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXX 393
G+ + +C+D C + C +A+ L C C G +
Sbjct: 2563 GFTQHSQWAQCVDENE--C--ALSPPTCGSASCRNTLGGFRCVCPSGFDFDQA------- 2611
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
L G C+DVDECA C+ +C NT G + C CP G
Sbjct: 2612 ----------LGG--CQDVDECAGRRGPCSY-SCANTPGGFLCGCPQG 2646
Score = 150 bits (363), Expect = 1e-35
Identities = 94/281 (33%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
MC NG+C N DG F C+CKPG+ G C D+DEC+ P +C G C NT GS+ C C
Sbjct: 547 MCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRCQC 605
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD-E 123
G A G C D S C G +GS C + T T+ C + +
Sbjct: 606 LGGLAVGTDGRVCVDTH---VRSTCYG---AIEKGS----CARPFPGTVTKSECCCANPD 655
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
C+ N+ F+ C G ++ DGR L V Y
Sbjct: 656 HGFGEPCQLCPAKNS-AEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRC 714
Query: 184 LCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDI 239
+C G G D++EC C +G C+N Y C C PG+H D +C+D+
Sbjct: 715 VCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDV 774
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
DEC S C G CRN AGS+TC C G+R +P C D
Sbjct: 775 DEC--LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD 813
Score = 145 bits (351), Expect = 3e-34
Identities = 82/235 (34%), Positives = 111/235 (47%), Gaps = 14/235 (5%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+CKN G F C C GY +G C+D+DEC C+ C NT G++TC C PGF
Sbjct: 2426 LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGFT 2484
Query: 71 PTAAGYCADVDECAADSMCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
C D DEC+A G G C N+ GSF+C C G+ ++ C DV+EC+
Sbjct: 2485 QHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPH 2543
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL----YAVL 184
C++G C N G +RC C GFT + C+ + +S C + + +
Sbjct: 2544 RCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVD-ENECALSPPTCGSASCRNTLGGFRCV 2601
Query: 185 CPEGPSKDN--GGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
CP G D GG D++EC G C + SC N G+ C C GY G C
Sbjct: 2602 CPSGFDFDQALGGCQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHC 2655
Score = 123 bits (296), Expect = 1e-27
Identities = 69/186 (37%), Positives = 88/186 (47%), Gaps = 7/186 (3%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C +G C N G F C C G+ S G C DV+EC D P C+ G C+N G Y C
Sbjct: 2501 GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHG-CQNQLGGYRC 2558
Query: 64 LCEPGFAPTAA-GYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C GF + C D +ECA + C C N+ G F+CVC +G+ G C DV
Sbjct: 2559 SCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2618
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
DEC +R + C NTPG F C C G+ + G G LG+ Q P + L
Sbjct: 2619 DECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSG--LGFSPGPQDTPDKEELLS 2676
Query: 182 AVLCPE 187
+ C E
Sbjct: 2677 SEACYE 2682
Score = 116 bits (280), Expect = 1e-25
Identities = 120/476 (25%), Positives = 168/476 (35%), Gaps = 73/476 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C G C+N+ G F CIC GYE G C D++EC D P C G C NT GSY C
Sbjct: 1418 GNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLC 1476
Query: 64 LCEPGFAPTAAGY-CADV--DECAADSMCKGGRCVNSEGSF-------QCVCEAGYRPTA 113
C F +G C D C ++ +G ++ C C G
Sbjct: 1477 SCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGN 1536
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSF--------RCECLPGFTLSNDGRTCLGLKLG 165
C + E + +C G P C+ LPG D G
Sbjct: 1537 PCELCPMANTTEYRTLCPGGEGFQ-PNRITVILEDIDECQELPGLCQGGDCVNTFG---- 1591
Query: 166 WGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICD 225
C+ P + +C DI+EC+ G C G+C N Y C+C
Sbjct: 1592 -SFQCECPPGYHLSEHTRICE----------DIDECSTHSGICGPGTCYNTLGNYTCVCP 1640
Query: 226 PGY-HPDADGLCRDIDECDMHQSYCAGGQCRNT-AGSFT---CVCPE--GTRHEPELQLC 278
Y + C D+ + + Y G C+N A + T C C G + C
Sbjct: 1641 AEYLQVNGGNNCMDMRKSVCFRHY--NGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEAC 1698
Query: 279 R-----DIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECE 333
D G ++ +D G P E+ + C NG CIN G F CEC
Sbjct: 1699 PTPISPDYQILCGNQAPGFL-TDIHTGK-PLDIDECGEIPAICANGICINQIGSFRCECP 1756
Query: 334 LGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXX 393
G+ ++ C D C R Q A + C C+
Sbjct: 1757 AGFNYNSILLACEDV--DECGSRESPCQQNADCINIPGSYRCKCT--------------- 1799
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+G+ G C +EC +C+ G C++T+GSY C C G + T
Sbjct: 1800 -----RGYKLSPGGACVGQNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQT 1850
Score = 75.8 bits (178), Expect = 3e-13
Identities = 48/138 (34%), Positives = 63/138 (45%), Gaps = 9/138 (6%)
Query: 316 CDNG-RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NG RCI G C C G+ + +R D R G C+ +V C+ L+ +
Sbjct: 162 CHNGGRCI---GPNRCACVYGF-MGPQCER--DYRTGPCFGQVGPEGCQHQLTGLVCTKA 215
Query: 375 -CCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVNTDG 432
CC +VG AWG +GF + C+DVDEC LC GG+CVN G
Sbjct: 216 LCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVG 275
Query: 433 SYRCDCPPGLTLDSTGTA 450
S+ C CP G L + A
Sbjct: 276 SFHCRCPVGHRLSDSSAA 293
Score = 70.5 bits (165), Expect = 1e-11
Identities = 79/272 (29%), Positives = 97/272 (35%), Gaps = 45/272 (16%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT 72
N+ G F C PG+ + + C V CR R C G C C C G
Sbjct: 65 NVCGSRFHAYCCPGWRTFPGRSQCV-VPICR---RACGEGFCSQPN---LCTCADGTLAP 117
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
+ G C+ M GG C + C+C+ GY T D R C N
Sbjct: 118 SCGVSRG-SGCSVSCM-NGGTCRGAS----CLCQKGYTGTVCGQPICD-------RGCHN 164
Query: 133 G-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
G RC G RC C+ GF G C+ G + + PEG
Sbjct: 165 GGRCI---GPNRCACVYGFM---------------GPQCERDYRTGP-CFGQVGPEGCQH 205
Query: 192 DNGGADINE--CTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDMHQSY 248
G + C A G CE L P C G+ P+ G C+D+DEC
Sbjct: 206 QLTGLVCTKALCCATVGRAWGLPCE-LCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGL 264
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD 280
C GG C N GSF C CP G R C D
Sbjct: 265 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 296
Score = 61.7 bits (143), Expect = 5e-09
Identities = 23/70 (32%), Positives = 35/70 (50%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C+N G F C C +G+ L ++ C D R G+C+ + G+C R++C
Sbjct: 265 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQC 324
Query: 376 CCSVGLAWGS 385
CC G W +
Sbjct: 325 CCDRGRCWAA 334
Score = 55.6 bits (128), Expect = 3e-07
Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C G+ P GAC DVDEC+ +C+ G C N GSF C C G LS+ C +
Sbjct: 239 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 298
Query: 164 LG 165
G
Sbjct: 299 AG 300
Score = 41.5 bits (93), Expect = 0.006
Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
C DVDEC S C G CVN G+Y C C PG T A
Sbjct: 454 CIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQA 493
Score = 40.3 bits (90), Expect = 0.014
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 5/68 (7%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCR-NTAGSYT- 62
G+C G C N+ G F C C G+ A C D V GRC + AG YT
Sbjct: 263 GLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDY-RAGACFSVLFGGRCAGDLAGHYTR 321
Query: 63 --CLCEPG 68
C C+ G
Sbjct: 322 RQCCCDRG 329
>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
Length = 2911
Score = 300 bits (737), Expect = 6e-81
Identities = 177/497 (35%), Positives = 228/497 (45%), Gaps = 56/497 (11%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
+ +C NG C + C C GY+ + G C DVDEC NP C G C NT GSY
Sbjct: 500 HANLCLNGRCIPTVSSYRCECNMGYKQDANGD-CIDVDECTSNP--CTNGDCVNTPGSYY 556
Query: 63 CLCEPGFAPTAAGY-CADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C GF T C D+DEC + +CK GRCVNS+GSFQC+C AG+ T CVD
Sbjct: 557 CKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELTTDGKNCVD 616
Query: 121 VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL--------GLKLG------- 165
DEC +C NG C N GSF+C C PGF L+ +GR C G+ +
Sbjct: 617 HDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSE 676
Query: 166 WGVSCQACPAQGSELYAVLCPEGPSKDN--GGADINECT-AVPGACPHGS--CENLEPGY 220
C P + +C + + GG C PGA C N + G+
Sbjct: 677 GSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGF 736
Query: 221 RCICDP---GYHPDADGLC----------RDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
C P + GLC RDI+EC + CA G C N GS+ C C
Sbjct: 737 GEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNS 796
Query: 268 GTRHEPELQLCRDIDECE------GETETHYIESDYERGDIPPTFPTRTEL--------- 312
G + + C DIDEC Y PP + RTE
Sbjct: 797 GYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYS-CTCPPGYVFRTETETCEDINEC 855
Query: 313 -ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLL 371
++PC NG C N G F CEC G L +T C+D+ +G+CW + D +CE L
Sbjct: 856 ESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATL 915
Query: 372 RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTD 431
+ ECC ++G AWGS +G A++ G TC DV+EC + +C G CVN+
Sbjct: 916 KSECCATLGAAWGS-PCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSK 974
Query: 432 GSYRCDCPPGLTLDSTG 448
GS+ C+CP GLTLD TG
Sbjct: 975 GSFHCECPEGLTLDGTG 991
Score = 267 bits (654), Expect = 6e-71
Identities = 165/493 (33%), Positives = 224/493 (45%), Gaps = 55/493 (11%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
GMCT G C+N G F+C C G+ E C D+DECR +P +C G C NT GS+ C
Sbjct: 1081 GMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECE 1140
Query: 65 CEPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C G+ C D+D C + +C+GG CVN+EGSFQC C G+ + +R CVD+
Sbjct: 1141 CFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDI 1200
Query: 122 DECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQ 176
+EC +CRNG+C N G+++C C PG+ + D + C + + G Q ++
Sbjct: 1201 NECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSE 1260
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
GS Y C EG + G ADI+EC P C G C N+ YRC+C G+ D
Sbjct: 1261 GS--YECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMD 1318
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C D++ECD++ + C G+C NT GSF C C G + C D+DEC E H
Sbjct: 1319 MKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDEC--EIGAHN 1376
Query: 293 IESDYERGDIPPTFPTRTELA-----------SPCDNG--------RCINTHGGFECECE 333
+ +IP +F C NG +C+NT G + C C
Sbjct: 1377 CDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACS 1436
Query: 334 LGYVLD----ATAQRCLDN----RRGSCWRRVVDGQCEAA---APELLLR-----QECCC 377
G+ D + C +N G C +CE P R EC
Sbjct: 1437 EGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSF 1496
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYR 435
G+ G+ +LD G C D+DECA C G CVNT G Y
Sbjct: 1497 QNICVSGTCNNLPGMFHCICDDGY-ELDRTGGNCTDIDECADPIN-CVNGLCVNTPGRYE 1554
Query: 436 CDCPPGLTLDSTG 448
C+CPP L+ TG
Sbjct: 1555 CNCPPDFQLNPTG 1567
Score = 249 bits (610), Expect = 1e-65
Identities = 149/450 (33%), Positives = 213/450 (47%), Gaps = 48/450 (10%)
Query: 19 FECICK--PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT-AAG 75
F+ IC PG+ D+DEC++ P +C G C N GS+ C C GF+
Sbjct: 1786 FKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLL 1845
Query: 76 YCADVDECA-ADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRN 132
C D+DEC+ D++C + C+NS GS++C C AG++ + GACVD +EC E VC +
Sbjct: 1846 VCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFK-LSPNGACVDRNECLEIPNVCSH 1904
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE-LYAVLCPEG--P 189
G C + GS++C C GF S D C+ + C + + Y LC G
Sbjct: 1905 GLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFEL 1964
Query: 190 SKDNGGADINECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQS 247
+ +N DI+EC++ G C +G C N ++C+C+ GY DG C D +EC
Sbjct: 1965 THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPG 2024
Query: 248 YCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFP 307
C+ G C+N GSF C+CP G +E + + C DI+EC+ +
Sbjct: 2025 SCSPGTCQNLEGSFRCICPPG--YEVKSENCIDINECDEDPNI----------------- 2065
Query: 308 TRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAP 367
C G C NT GGF+C C G+VL +RC D R+ C+ +G+C
Sbjct: 2066 --------CLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKA 2117
Query: 368 ELLLRQECCCS--VGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-------RDVDECALS 418
+ +CCCS G WG + T DV+EC S
Sbjct: 2118 FNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLES 2177
Query: 419 AELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+C+ G C+NTDGS+RC+CP G LD TG
Sbjct: 2178 PGICSNGQCINTDGSFRCECPMGYNLDYTG 2207
Score = 241 bits (591), Expect = 3e-63
Identities = 153/452 (33%), Positives = 210/452 (46%), Gaps = 41/452 (9%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC 63
G+C NG+C N G F C C G+ +C D+DEC + +C+R C N+ GSY C
Sbjct: 1816 GICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRC 1875
Query: 64 LCEPGFAPTAAGYCADVDEC-AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C GF + G C D +EC ++C G CV+ +GS+QC+C G++ + + C+DVD
Sbjct: 1876 ECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVD 1935
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG---SE 179
EC E+ C NG C NT GS+ C C PGF L+++ CL + Q C G +E
Sbjct: 1936 EC-ERHPCGNGTCKNTVGSYNCLCYPGFELTHN-NDCLDIDECSSFFGQVC-RNGRCFNE 1992
Query: 180 L--YAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
+ + LC EG G D NEC A+PG+C G+C+NLE +RCIC PGY ++
Sbjct: 1993 IGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN 2052
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
C DI+ECD + C G C NT G F C+CP G + C D T +
Sbjct: 2053 -CIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD-------TRQSFCF 2104
Query: 295 SDYERG--DIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYVLDATAQRCLDNRRG 351
+++E G +P F T A C C G G+ CEL D A + L
Sbjct: 2105 TNFENGKCSVPKAF--NTTKAKCC----CSKMPGEGWGDPCELCPKDDEVAFQDLCPYGH 2158
Query: 352 SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD--GATC 409
+ D + + EC S G+ LD G C
Sbjct: 2159 GTVPSLHDTREDV--------NECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRC 2210
Query: 410 RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
D DEC++ C GTC N GS+ C+C G
Sbjct: 2211 VDTDECSI-GNPCGNGTCTNVIGSFECNCNEG 2241
Score = 238 bits (583), Expect = 3e-62
Identities = 161/465 (34%), Positives = 212/465 (45%), Gaps = 56/465 (12%)
Query: 2 TNG-GMCT-NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAG 59
+NG +C N C N G + C C G++ GA C D +EC + P VC G C + G
Sbjct: 1854 SNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGA-CVDRNECLEIPNVCSHGLCVDLQG 1912
Query: 60 SYTCLCEPGF-APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC 118
SY C+C GF A C DVDEC C G C N+ GS+ C+C G+ T C
Sbjct: 1913 SYQCICHNGFKASQDQTMCMDVDECERHP-CGNGTCKNTVGSYNCLCYPGFELTHNND-C 1970
Query: 119 VDVDECEE--QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACP 174
+D+DEC +VCRNGRC N GSF+C C G+ L+ DG+ C+ + SC
Sbjct: 1971 LDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGT 2030
Query: 175 AQGSE-LYAVLCPEGPS-KDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
Q E + +CP G K DINEC P C GSC N G++C+C PG+
Sbjct: 2031 CQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSD 2090
Query: 233 DGL-CRDIDE--C--DMHQSYCAGGQCRNTAGSFTCVCPE--GTRHEPELQLCRDIDECE 285
+G C D + C + C+ + NT + C C + G +LC DE
Sbjct: 2091 NGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKA-KCCCSKMPGEGWGDPCELCPKDDEVA 2149
Query: 286 GETETHYIESDYERGDIPPTFPTRTE----LASP--CDNGRCINTHGGFECECELGYVLD 339
+ Y G +P TR + L SP C NG+CINT G F CEC +GY LD
Sbjct: 2150 FQDLC-----PYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLD 2204
Query: 340 ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK 399
T RC+D S +G C ++ EC C+ +
Sbjct: 2205 YTGVRCVDTDECSIGNPCGNGTC----TNVIGSFECNCN--------------------E 2240
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
GF C D++ECA + LCA C+NT GSY C CP G L
Sbjct: 2241 GFEPGPMMNCEDINECAQNPLLCA-LRCMNTFGSYECTCPIGYAL 2284
Score = 233 bits (570), Expect = 9e-61
Identities = 150/468 (32%), Positives = 202/468 (43%), Gaps = 49/468 (10%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RGR-CRNTAGSYTCLCEPGF 69
C N G +EC C GY + +C+D+DEC + C RG C+N G++ C+C PG
Sbjct: 2267 CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGM 2326
Query: 70 APTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
A G C D +EC +C+ GRCVN GS++C C G++ +++ C+D
Sbjct: 2327 ARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDN------ 2380
Query: 128 RVCRNGRCHNTPGSFRCECLPGF-TLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCP 186
R G C C+ L C GWG C+ CP G+ Y +CP
Sbjct: 2381 ---RQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICP 2437
Query: 187 EGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMH 245
GP G DI+EC +P C +G C N +RC C GY D G C D+DEC
Sbjct: 2438 HGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQS 2497
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI--- 302
C C+NT GS+ C CP G + + + C+D+DEC+ + G
Sbjct: 2498 PKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCK 2556
Query: 303 -PPTFP-------TRTELASP---C-DNGRCINTHGGFECECELGYVLDATAQRCLD--- 347
PP F E S C G C NT G F CEC+ G+ LDAT C D
Sbjct: 2557 CPPGFTQHHTACIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDE 2616
Query: 348 ---NRRGSCWRRVVDGQCEAAAPELLLR----QECC----CSVGLAWGSXXXXXXXXXXX 396
N R + + G P+ ++ +C CS A GS
Sbjct: 2617 CDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYK 2676
Query: 397 XX--KGFA-KLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF+ + C DV+EC+ S C G C NT+G Y C CPPG
Sbjct: 2677 CACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPG 2723
Score = 224 bits (547), Expect = 6e-58
Identities = 147/450 (32%), Positives = 198/450 (44%), Gaps = 53/450 (11%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NGIC+N+ G + C C GYE + G C D+DEC N +C G CRNT GSY+C C
Sbjct: 777 ICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTC 836
Query: 66 EPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
PG+ T C D++EC ++ C G C N+ GSF C C G + ++T C+D
Sbjct: 837 PPGYVFRTETETCEDINECESNP-CVNGACRNNLGSFNCECSPGSKLSSTGLICID---- 891
Query: 125 EEQRVCRNGRCHNTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
G C RCE + G TL ++ C L WG C+ C EL
Sbjct: 892 -----SLKGTCWLNIQDSRCEVNINGATLKSE--CCATLGAAWGSPCERC-----EL-DT 938
Query: 184 LCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDID 240
CP G ++ G D+NEC PG CP+G C N + + C C G D G +C DI
Sbjct: 939 ACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIR 998
Query: 241 ECDMHQSYCAGGQCRNTAGSF---TCVCPEGTRHEPELQLCRDIDECEGETETHYIESDY 297
+ + G F C C G E + C E ET
Sbjct: 999 MEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFA 1058
Query: 298 ERGDIPPTFPTRTEL----ASP--CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRG 351
RGD+ P ++ A P C G+C NT G F+C C G+ LD + C D
Sbjct: 1059 NRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD---- 1114
Query: 352 SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRD 411
+D +C +P+L C G+ + GF + C D
Sbjct: 1115 ------ID-ECR-ISPDL-------CGSGICVNTPGSFECECFEGYESGFMMM--KNCMD 1157
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+D C + LC GGTCVNT+GS++CDCP G
Sbjct: 1158 IDGCERNPLLCRGGTCVNTEGSFQCDCPLG 1187
Score = 223 bits (546), Expect = 8e-58
Identities = 139/448 (31%), Positives = 191/448 (42%), Gaps = 42/448 (9%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
N C N G + C C G+ +G C DVDEC +N +C G+C N G+Y C CE G
Sbjct: 1421 NAQCVNTPGSYRCACSEGFTG--DGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMG 1478
Query: 69 FAPTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
F P + + C D+DEC+ ++C G C N G F C+C+ GY T G C D+DEC +
Sbjct: 1479 FTPASDSRSCQDIDECSFQNICVSGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADP 1538
Query: 128 RVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
C NG C NTPG + C C P F L+ G C+ ++G GS
Sbjct: 1539 INCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGV 1598
Query: 188 GPSKDNGGADINECTAVP-GACPHGSCENLEPGYRCICDPGYHPD-ADGLCRDIDECDMH 245
G S+ + + + P CP + E C G+ P+ + DIDEC
Sbjct: 1599 GVSRSSCCCSLGKAWGNPCETCP--PVNSTEYYTLCPGGEGFRPNPITIILEDIDECQEL 1656
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
C GG C NT GSF C CP+G + ++C DIDEC + Y T
Sbjct: 1657 PGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYN------T 1710
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
T + P + +GG C +D R+ C+R CE
Sbjct: 1711 LGNYTCICPP----EYMQVNGGHNC---------------MDMRKSFCYRSYNGTTCENE 1751
Query: 366 APELLLRQECCC--SVGLAWGSXXXXXXXXXXXXXK-------GFA-KLDGATCRDVDEC 415
P + ++ CCC +VG A K GF + D+DEC
Sbjct: 1752 LPFNVTKRMCCCTYNVGKAGNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDEC 1811
Query: 416 ALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+CA G C+N GS+RC+CP G +
Sbjct: 1812 KEIPGICANGVCINQIGSFRCECPTGFS 1839
Score = 213 bits (521), Expect = 8e-55
Identities = 159/493 (32%), Positives = 213/493 (43%), Gaps = 76/493 (15%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGAL-CRDVDE---------CRDNPR----VCR 50
G C+ G C+N++G F CIC PGYE SE + + DE C + P +C
Sbjct: 2024 GSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCP 2083
Query: 51 RG--------RCRNTAGSYTCLC--EPGFAPTAAGYCADVDECAADSMCK---GGRCV-- 95
G RC +T S+ C E G + +C M G C
Sbjct: 2084 PGFVLSDNGRRCFDTRQSF-CFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELC 2142
Query: 96 --NSEGSFQCVCEAGYRPTAT-RGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFT 151
+ E +FQ +C G+ + DV+EC E +C NG+C NT GSFRCEC G+
Sbjct: 2143 PKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYN 2202
Query: 152 LSNDGRTCLGL-KLGWGVSCQ--ACP-AQGSELYAVLCPEG--PSKDNGGADINECTAVP 205
L G C+ + G C C GS + C EG P DINEC P
Sbjct: 2203 LDYTGVRCVDTDECSIGNPCGNGTCTNVIGS--FECNCNEGFEPGPMMNCEDINECAQNP 2260
Query: 206 GACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDEC--DMHQSYCAGGQCRNTAGSFT 262
C C N Y C C GY D +C+D+DEC +H G C+N G+F
Sbjct: 2261 LLCAL-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFM 2319
Query: 263 CVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCI 322
C+CP G P+ + C D +EC RT+ C+NGRC+
Sbjct: 2320 CICPPGMARRPDGEGCVDENEC------------------------RTK-PGICENGRCV 2354
Query: 323 NTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAP--ELLLRQECCCSVG 380
N G + CEC G+ ++ CLDNR+G C+ V+ C+ A+ L+ + ECCC G
Sbjct: 2355 NIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGG 2414
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKL-DGATC--RDVDECALSAELCAGGTCVNTDGSYRCD 437
WG K G T RD+DEC + LC G C+NT GS+RC
Sbjct: 2415 RGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCF 2474
Query: 438 CPPGLTLDSTGTA 450
C G T D +GT+
Sbjct: 2475 CKVGYTTDISGTS 2487
Score = 211 bits (515), Expect = 4e-54
Identities = 156/455 (34%), Positives = 193/455 (42%), Gaps = 75/455 (16%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C NG C N+ G FEC C G+E G C D++EC NP +C RC NT GSY C
Sbjct: 2219 GNPCGNGTCTNVIGSFECNCNEGFEPGPM-MNCEDINECAQNPLLCAL-RCMNTFGSYEC 2276
Query: 64 LCEPGFAPTA-AGYCADVDECAA---DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C G+A C D+DECA D +G C N G+F C+C G CV
Sbjct: 2277 TCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCV 2336
Query: 120 DVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
D +EC + +C NGRC N GS+RCEC GF S+ G CL + G C A
Sbjct: 2337 DENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGL---CFA------ 2387
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLE-PG---YRCICDPGYHPDADG 234
E+ +C S N +EC G CE PG Y+ IC G DG
Sbjct: 2388 EVLQTICQMASSSRNLVTK-SECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDG 2446
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
RDIDEC + + C GQC NT GSF C C G + C D+DEC
Sbjct: 2447 --RDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDEC---------- 2494
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCW 354
++ PC N C NT G ++C C GYVL + C D C
Sbjct: 2495 ---------------SQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTCKD--LDECQ 2536
Query: 355 RRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDE 414
+ C+ L C C GF + A C D +E
Sbjct: 2537 TK--QHNCQFLCVNTLGGFTCKCP--------------------PGFTQHHTA-CIDNNE 2573
Query: 415 CALSAELCAG-GTCVNTDGSYRCDCPPGLTLDSTG 448
C LC G G C NT GS+ C+C G +LD+TG
Sbjct: 2574 CGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATG 2608
Score = 203 bits (496), Expect = 9e-52
Identities = 162/509 (31%), Positives = 211/509 (41%), Gaps = 78/509 (15%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGS 60
+ N +C NG+C+N G + C C PGY +E C D++EC NP C G CRN GS
Sbjct: 814 LVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNP--CVNGACRNNLGS 871
Query: 61 YTCLCEPGFAPTAAG-YCAD--VDEC---AADSMCK---GGRCVNSE------GSFQCVC 105
+ C C PG ++ G C D C DS C+ G + SE ++ C
Sbjct: 872 FNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPC 931
Query: 106 EAGYRPTA-TRG-------ACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
E TA RG C DV+ECE VC NGRC N+ GSF CEC G TL G
Sbjct: 932 ERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTG 991
Query: 157 RTCLGLK-----LGWGVSCQACPAQGS-ELYAVLCPEGPSKDNGGADINECTAVPGACPH 210
R CL ++ L W P G + A C G + G + EC PG +
Sbjct: 992 RVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAA---WGTECEECPK-PGTKEY 1047
Query: 211 GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR 270
E L P + G +DI+EC C G+CRNT GSF C C G
Sbjct: 1048 ---ETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFA 1104
Query: 271 HEPELQLCRDIDECE---------------GETETHYIESDYERGDIPPTFPTRTE--LA 313
+ E + C DIDEC G E E YE G + +
Sbjct: 1105 LDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEG-YESGFMMMKNCMDIDGCER 1163
Query: 314 SP--CDNGRCINTHGGFECECELGYVLDATAQRCLD----------NRRGSCWRRVVDGQ 361
+P C G C+NT G F+C+C LG+ L + + C+D R G C + Q
Sbjct: 1164 NPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQ 1223
Query: 362 CEA-----AAPE---LLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL-DGATCRDV 412
C A P+ EC G +G+A + DG +C D+
Sbjct: 1224 CSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADI 1283
Query: 413 DECALSAELCAGGTCVNTDGSYRCDCPPG 441
DEC + ++C GG C N G YRC C G
Sbjct: 1284 DECENNPDICDGGQCTNIPGEYRCLCYDG 1312
Score = 200 bits (488), Expect = 8e-51
Identities = 144/457 (31%), Positives = 195/457 (42%), Gaps = 44/457 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C NI G + C+C G+ + + C DV+EC N +C G C NT GS+
Sbjct: 1289 NPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFI 1348
Query: 63 CLCEPGFA-PTAAGYCADVDEC--AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C+ G++ C DVDEC A + C+N GSF+C C G+ + C+
Sbjct: 1349 CHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIK--CI 1406
Query: 120 DVDECEE--QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-----KLGWGVSCQA 172
D+DEC + N +C NTPGS+RC C GFT DG TC + + + Q
Sbjct: 1407 DLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVDECAENINLCENGQC 1464
Query: 173 CPAQGSELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
G+ Y C G P+ D+ DI+EC + C G+C NL + CICD GY
Sbjct: 1465 LNVPGA--YRCECEMGFTPASDSRSCQDIDEC-SFQNICVSGTCNNLPGMFHCICDDGYE 1521
Query: 230 PD-ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET 288
D G C DIDEC C G C NT G + C CP + P C +D G
Sbjct: 1522 LDRTGGNCTDIDEC-ADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGC--VDNRVGNC 1578
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDN 348
Y++ RGD + TE+ C C C LG + C
Sbjct: 1579 ---YLKFG-PRGD--GSLSCNTEIGVGVSRSSC--------C-CSLGKAWGNPCETCPPV 1623
Query: 349 RRGSCWRRVVDGQCEAAAPELLLRQ---ECCCSVGLA-WGSXXXXXXXXXXXXXKG-FAK 403
+ G+ P ++ + EC GL G+ +G +
Sbjct: 1624 NSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLS 1683
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPP 440
D C D+DEC +C GTC NT G+Y C CPP
Sbjct: 1684 EDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPP 1720
Score = 197 bits (481), Expect = 6e-50
Identities = 138/429 (32%), Positives = 186/429 (43%), Gaps = 47/429 (10%)
Query: 35 LCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRC 94
L + +D C+ + +C GRC T SY C C G+ A G C DVDEC ++ C G C
Sbjct: 490 LNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNP-CTNGDC 548
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV-CRNGRCHNTPGSFRCECLPGFTLS 153
VN+ GS+ C C AG++ T T+ AC+D+DEC + V C+NGRC N+ GSF+C C GF L+
Sbjct: 549 VNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELT 608
Query: 154 NDGRTCLGL-KLGWGVSC--QACPAQGSELYAVLCPEGPSKDNGG--ADINECTAVPGAC 208
DG+ C+ + C C + + P NG D++EC PG C
Sbjct: 609 TDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDEC-QTPGIC 667
Query: 209 PHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC-RNTAGSFT---C 263
+G C N E +RC C PG DG +C D G C R G+ T C
Sbjct: 668 MNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSEC 727
Query: 264 VC--PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTEL-ASPCDNGR 320
C P+ EP Q C + E H + S + L C NG
Sbjct: 728 CCANPDYGFGEP-CQPC----PAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGI 782
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCEAAAPELLLRQECCCSV 379
C N G + C C GY DA+ + C+D R + D G C C C
Sbjct: 783 CENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGS----YSCTCPP 838
Query: 380 GLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
G + + + TC D++EC + C G C N GS+ C+C
Sbjct: 839 GYVF-------------------RTETETCEDINEC--ESNPCVNGACRNNLGSFNCECS 877
Query: 440 PGLTLDSTG 448
PG L STG
Sbjct: 878 PGSKLSSTG 886
Score = 194 bits (474), Expect = 4e-49
Identities = 162/523 (30%), Positives = 214/523 (40%), Gaps = 89/523 (17%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDV-----------DEC-RDNPRVCRRG 52
G+C NG C N G F C C G G +C D+ DEC P R
Sbjct: 963 GVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMD 1022
Query: 53 RCRNTAGS----------------YTCLCE--PGFAP-----TAAGYCADVDECAA-DSM 88
C G+ Y LC GFA T + D++EC A M
Sbjct: 1023 ACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGM 1082
Query: 89 CKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECL 147
C G+C N+ GSF+C C +G+ C D+DEC +C +G C NTPGSF CEC
Sbjct: 1083 CTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECF 1142
Query: 148 PG----FTLSNDGRTCLGLKLGWGVSCQACPAQGSE-LYAVLCPEG----PSKDNGGADI 198
G F + + G + + C+ +E + CP G PS+++ DI
Sbjct: 1143 EGYESGFMMMKNCMDIDGCERN-PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDC-VDI 1200
Query: 199 NECTAVPGACPHGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYCAGGQCRN 256
NEC+ C +G C N+ Y+C C+PGY PD G C DIDEC + C QC N
Sbjct: 1201 NECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQG-CTDIDECMIMNGGC-DTQCTN 1258
Query: 257 TAGSFTCVCPEGTRHEPELQLCRDIDECEGET------ETHYIESDYE---RGDIPPTFP 307
+ GS+ C C EG P+ + C DIDECE + I +Y +
Sbjct: 1259 SEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMD 1318
Query: 308 TRTEL-ASPCD-------NGRCINTHGGFECECELGYVLDATAQRCLD-----------N 348
+T + + CD G C NT G F C C+LGY + C D +
Sbjct: 1319 MKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCD 1378
Query: 349 RRGSCWRRVVDGQCEAAAPELLLRQECC----CSVGLAWGSXXX----XXXXXXXXXXKG 400
SC +C + +C CS G S +G
Sbjct: 1379 MHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEG 1438
Query: 401 FAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
F DG TC DVDECA + LC G C+N G+YRC+C G T
Sbjct: 1439 FTG-DGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFT 1480
Score = 193 bits (470), Expect = 1e-48
Identities = 151/497 (30%), Positives = 204/497 (41%), Gaps = 64/497 (12%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
T MC NG+C N DG F+CICKPG+ G C DVDEC+ P +C G C N+ GS+
Sbjct: 621 TTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQ-TPGICMNGHCINSEGSF 679
Query: 62 TCLCEPGFAPTAAG-YCADVD-ECAADSMCKGGRCV----NSEGSFQCVC---EAGY--- 109
C C PG A G C D K G CV + +C C + G+
Sbjct: 680 RCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEP 739
Query: 110 -RPTATR------GACV----------DVDECE-EQRVCRNGRCHNTPGSFRCECLPGFT 151
+P + G C D++EC + +C NG C N GS+RC C G+
Sbjct: 740 CQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYE 799
Query: 152 LSNDGRTCLGLK--LGWGVSCQACPAQGSE-LYAVLCPEG---PSKDNGGADINECTAVP 205
GR C+ + L + C + + Y+ CP G ++ DINEC + P
Sbjct: 800 PDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNP 859
Query: 206 GACPHGSCENLEPGYRCICDPGYHPDADGL-CRDI--DEC--DMHQSYCAGGQCRNTAGS 260
C +G+C N + C C PG + GL C D C ++ S C T S
Sbjct: 860 --CVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKS 917
Query: 261 FTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR 320
C G + C ++D E + FP C NGR
Sbjct: 918 -ECCATLGAAWGSPCERC-ELDTACPRGLARIKGVTCEDVNECEVFP------GVCPNGR 969
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C+N+ G F CEC G LD T + CLD R C+ + + +C P CCC+VG
Sbjct: 970 CVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVG 1029
Query: 381 LAWGSX-------XXXXXXXXXXXXKGFAK----LDGAT-CRDVDECALSAELCAGGTCV 428
AWG+ GFA L G +D++EC +C G C
Sbjct: 1030 AAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCR 1089
Query: 429 NTDGSYRCDCPPGLTLD 445
NT GS++C C G LD
Sbjct: 1090 NTIGSFKCRCNSGFALD 1106
Score = 192 bits (468), Expect = 2e-48
Identities = 133/452 (29%), Positives = 194/452 (42%), Gaps = 46/452 (10%)
Query: 13 KNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
K+ + F+ +C G+ + S DV+EC ++P +C G+C NT GS+ C C G+
Sbjct: 2144 KDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNL 2203
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
G C D DEC+ + C G C N GSF+C C G+ P C D++EC + +
Sbjct: 2204 DYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMN-CEDINECAQNPLL 2262
Query: 131 RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGV-SCQACPAQGSEL---YAVLC 185
RC NT GS+ C C G+ L D + C L + G+ C++ L + +C
Sbjct: 2263 CALRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCIC 2322
Query: 186 PEGPSK---DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDE 241
P G ++ G D NEC PG C +G C N+ YRC C+ G+ + G C D +
Sbjct: 2323 PPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQ 2382
Query: 242 ----CDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE-GETETHYIES 295
++ Q+ C RN C C G + +LC + + H
Sbjct: 2383 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGY 2442
Query: 296 DYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWR 355
+ DI + + C NG+CINT G F C C++GY D + C+D S
Sbjct: 2443 TTDGRDIDEC----KVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSP 2498
Query: 356 RVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDEC 415
+ + C+ +C C G + DG TC+D+DEC
Sbjct: 2499 KPCNYICKNTEGS----YQCSCPRGYV-------------------LQEDGKTCKDLDEC 2535
Query: 416 ALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
C CVNT G + C CPPG T T
Sbjct: 2536 QTKQHNCQ-FLCVNTLGGFTCKCPPGFTQHHT 2566
Score = 186 bits (453), Expect = 1e-46
Identities = 141/465 (30%), Positives = 185/465 (39%), Gaps = 76/465 (16%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C G C N G FEC C G++ C D+DEC P +C G C NT GSY C+
Sbjct: 284 GICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCV 343
Query: 65 CEPGFAPTAAG-YCADVDECAADSMCKGGRCVNS----EGSFQCVCEAG--YRPTATRGA 117
C G+ + G C D S GRC QC CE G + A
Sbjct: 344 CPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEA 403
Query: 118 CVDVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQA-CPA 175
C E +R+C +G PGS PG T N G G G+G P
Sbjct: 404 CPVRGSEEYRRLCMDGLPMGGIPGS--AGSRPGGTGGN-GFAPSGNGNGYGPGGTGFIPI 460
Query: 176 QGSELYAVLCPEGPSKDNGG------------ADINECTAVPGACPHGSCENLEPGYRCI 223
G ++ G GG I+ C C +G C YRC
Sbjct: 461 PGGNGFSP-GVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCE 519
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDE 283
C+ GY DA+G C D+DEC + C G C NT GS+ C C G + P Q C DIDE
Sbjct: 520 CNMGYKQDANGDCIDVDECTSNP--CTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDE 577
Query: 284 CEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQ 343
C + G + C NGRC+N+ G F+C C G+ L +
Sbjct: 578 C------------IQNGVL-------------CKNGRCVNSDGSFQCICNAGFELTTDGK 612
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
C+D+ + ++G C +C C G
Sbjct: 613 NCVDHDECTTTNMCLNGMCINEDGSF----KCICKPGFVLAP------------------ 650
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+G C DVDEC + +C G C+N++GS+RCDCPPGL + G
Sbjct: 651 -NGRYCTDVDECQ-TPGICMNGHCINSEGSFRCDCPPGLAVGMDG 693
Score = 184 bits (449), Expect = 4e-46
Identities = 103/271 (38%), Positives = 130/271 (47%), Gaps = 13/271 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+CTNG C N G F C CK GY + G C D+DEC +P+ C C+NT GSY C C
Sbjct: 2458 LCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNY-ICKNTEGSYQCSC 2516
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DEC CVN+ G F C C G+ T AC+D +EC
Sbjct: 2517 PRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGF--TQHHTACIDNNEC 2574
Query: 125 EEQRVCRNGR--CHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSELY 181
Q + G+ C NTPGSF CEC GF+L G C + + CQ Y
Sbjct: 2575 GSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGY 2634
Query: 182 AVLCPEGPSKD---NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA-DGLCR 237
CP+G + N D NEC+ P AC SC N Y+C C G+ D C
Sbjct: 2635 RCGCPQGYIQHYQWNQCVDENECSN-PNACGSASCYNTLGSYKCACPSGFSFDQFSSACH 2693
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
D++EC ++ C G C NT G + C CP G
Sbjct: 2694 DVNECSSSKNPCNYG-CSNTEGGYLCGCPPG 2723
Score = 179 bits (436), Expect = 2e-44
Identities = 155/493 (31%), Positives = 195/493 (39%), Gaps = 86/493 (17%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTC 63
G+C+NG C N DG F C C GY G C D DEC NP C G C N GS+ C
Sbjct: 2179 GICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP--CGNGTCTNVIGSFEC 2236
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF P C D++ECA + + RC+N+ GS++C C GY + C D+DE
Sbjct: 2237 NCNEGFEPGPMMNCEDINECAQNPLLCALRCMNTFGSYECTCPIGYALREDQKMCKDLDE 2296
Query: 124 CEE-QRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLG-----LKLGWGVSCQACPA 175
C E C R C N G+F C C PG DG C+ K G + +
Sbjct: 2297 CAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNI 2356
Query: 176 QGSELYAVLCPEGPSKDNGGADINE-----CTA--VPGACP-HGSCENLEPGYRCICDPG 227
GS Y C EG + G + + C A + C S NL C CD G
Sbjct: 2357 IGS--YRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGG 2414
Query: 228 Y---H-----------------PDADGLCRD---IDECDMHQSYCAGGQCRNTAGSFTCV 264
H P G D IDEC + + C GQC NT GSF C
Sbjct: 2415 RGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCF 2474
Query: 265 CPEGTRHEPELQLCRDIDEC-EGETETHYI----ESDYE----RGDIPPTFPTRTELASP 315
C G + C D+DEC + +YI E Y+ RG + +
Sbjct: 2475 CKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDE 2534
Query: 316 CDNGR------CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPEL 369
C + C+NT GGF C+C G+ TA C+DN E + L
Sbjct: 2535 CQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTA--CIDNN-------------ECGSQPL 2579
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCV 428
L C G+ + +GF+ G C DVDEC C G C
Sbjct: 2580 L-----CGGKGICQNT----PGSFSCECQRGFSLDATGLNCEDVDECD-GNHRCQHG-CQ 2628
Query: 429 NTDGSYRCDCPPG 441
N G YRC CP G
Sbjct: 2629 NILGGYRCGCPQG 2641
Score = 171 bits (416), Expect = 4e-42
Identities = 122/385 (31%), Positives = 169/385 (43%), Gaps = 53/385 (13%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE--CRDN--PRVCR-RGRCRN 56
T G+C NG C NI G + C C G++S S G C D + C +C+ RN
Sbjct: 2343 TKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRN 2402
Query: 57 TAGSYTCLCE--------------PGFA------PTAAGYCA---DVDEC-AADSMCKGG 92
C C+ PG A P GY D+DEC ++C G
Sbjct: 2403 LVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNG 2462
Query: 93 RCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTL 152
+C+N+ GSF+C C+ GY + +C+D+DEC + N C NT GS++C C G+ L
Sbjct: 2463 QCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVL 2522
Query: 153 SNDGRTCLGLK--LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGAC- 208
DG+TC L +CQ + CP G ++ + D NEC + P C
Sbjct: 2523 QEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPLLCG 2582
Query: 209 PHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
G C+N + C C G+ DA GL C D+DECD + C G C+N G + C CP+
Sbjct: 2583 GKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR-CQHG-CQNILGGYRCGCPQ 2640
Query: 268 GTRHEPELQLCRDIDECE-----GETETHYIESDYE----RGDIPPTFPTR----TELAS 314
G + C D +EC G + Y+ G F + E +S
Sbjct: 2641 GYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSS 2700
Query: 315 ---PCDNGRCINTHGGFECECELGY 336
PC+ G C NT GG+ C C GY
Sbjct: 2701 SKNPCNYG-CSNTEGGYLCGCPPGY 2724
Score = 167 bits (407), Expect = 5e-41
Identities = 128/472 (27%), Positives = 180/472 (38%), Gaps = 65/472 (13%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C G C N G F+C C GY + +C D+DEC +P VC G C NT G+YTC+
Sbjct: 1658 GLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCI 1717
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C P + G+ C D+ + C S C E + T C
Sbjct: 1718 CPPEYMQVNGGHNCMDM---------RKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVG 1768
Query: 124 CEEQRVCRNGRCHNTPGS--FRCEC--LPGFTLSNDGRTCLGL---KLGWGVSCQACPAQ 176
+ C C TPG+ F+ C +PGFT + + K G+
Sbjct: 1769 KAGNKPCE--PC-PTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCIN 1825
Query: 177 GSELYAVLCPEGPSKDN---GGADINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDA 232
+ CP G S ++ DI+EC+ C + C N YRC C G+
Sbjct: 1826 QIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSP 1885
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE----GET 288
+G C D +EC + C+ G C + GS+ C+C G + + +C D+DECE G
Sbjct: 1886 NGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNG 1945
Query: 289 ETHYIESDY-----------ERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYV 337
Y D + C NGRC N G F+C C GY
Sbjct: 1946 TCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYE 2005
Query: 338 LDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXXXXX 396
L + C+D C + G C + L C C G
Sbjct: 2006 LTPDGKNCIDT--NEC--VALPGSCSPGTCQNLEGSFRCICPPGY--------------- 2046
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
++ C D++EC +C G+C NT G ++C CPPG L G
Sbjct: 2047 ------EVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNG 2092
Score = 163 bits (395), Expect = 2e-39
Identities = 120/389 (30%), Positives = 165/389 (42%), Gaps = 56/389 (14%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+CKN+ G F CIC PG +G C D +ECR P +C GRC N GSY C C GF
Sbjct: 2310 MCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQ 2369
Query: 71 PTAAG-YCADVDE--CAAD---SMCK-GGRCVNSEGSFQCVCEAG--------------- 108
+++G C D + C A+ ++C+ N +C C+ G
Sbjct: 2370 SSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGT 2429
Query: 109 --YRPTATRGACV-----DVDECEEQ-RVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
Y+ G D+DEC+ +C NG+C NT GSFRC C G+T G +C+
Sbjct: 2430 AQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCI 2489
Query: 161 GLKLGWGVSCQACP--AQGSE-LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCE 214
L S + C + +E Y CP G G D++EC C C
Sbjct: 2490 DLD-ECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF-LCV 2547
Query: 215 NLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEGTRHEP 273
N G+ C C PG+ C D +EC C G G C+NT GSF+C C G +
Sbjct: 2548 NTLGGFTCKCPPGF-TQHHTACIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDA 2606
Query: 274 ELQLCRDIDECEGETETHY----IESDYERGDIPPTF---------PTRTELASP--CDN 318
C D+DEC+G + I Y G P + E ++P C +
Sbjct: 2607 TGLNCEDVDECDGNHRCQHGCQNILGGYRCG-CPQGYIQHYQWNQCVDENECSNPNACGS 2665
Query: 319 GRCINTHGGFECECELGYVLDATAQRCLD 347
C NT G ++C C G+ D + C D
Sbjct: 2666 ASCYNTLGSYKCACPSGFSFDQFSSACHD 2694
Score = 159 bits (386), Expect = 2e-38
Identities = 84/235 (35%), Positives = 116/235 (49%), Gaps = 11/235 (4%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
N ICKN +G ++C C GY +G C+D+DEC+ C+ C NT G +TC C PG
Sbjct: 2502 NYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF-LCVNTLGGFTCKCPPG 2560
Query: 69 FAPTAAGYCADVDECAADSMCKGGR--CVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
F C D +EC + + GG+ C N+ GSF C C+ G+ AT C DVDEC+
Sbjct: 2561 FTQHHTA-CIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDG 2619
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGS-ELYAVL 184
C++G C N G +RC C G+ C+ + +C + + Y
Sbjct: 2620 NHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCA 2678
Query: 185 CPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
CP G S D + D+NEC++ C +G C N E GY C C PGY+ G C
Sbjct: 2679 CPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGYYRVGQGHC 2732
Score = 157 bits (380), Expect = 1e-37
Identities = 138/477 (28%), Positives = 185/477 (38%), Gaps = 59/477 (12%)
Query: 16 DGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT-CLCEPGFAPTAA 74
DG C + G S + C + + NP C N+ YT C GF P
Sbjct: 1587 DGSLSCNTEIGV-GVSRSSCCCSLGKAWGNP--CETCPPVNSTEYYTLCPGGEGFRPNPI 1643
Query: 75 GYCA-DVDECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCR 131
D+DEC +C+GG C+N+ GSFQC C GY + C D+DEC VC
Sbjct: 1644 TIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCG 1703
Query: 132 NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
G C+NT G++ C C P + N G C+ ++ + C Y E
Sbjct: 1704 PGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSF---CY-------RSYNGTTCENELP 1753
Query: 192 DNGGADINECTAVPGACPHGSCENL-EPG---YRCICD--PGYHPDA-DGLCRDIDECDM 244
N + CT G + CE PG ++ IC PG+ D G DIDEC
Sbjct: 1754 FNVTKRMCCCTYNVGKAGNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKE 1813
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG-----ETETHYIESDYE- 298
CA G C N GSF C CP G + L +C DIDEC + I S
Sbjct: 1814 IPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSY 1873
Query: 299 RGDIPPTFPTR-----------TELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD 347
R + F E+ + C +G C++ G ++C C G+ C+D
Sbjct: 1874 RCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMD 1933
Query: 348 ----NR----RGSCWRRVVDGQCEA-AAPELLLRQECC----CSVGLAW----GSXXXXX 390
R G+C V C EL +C CS G
Sbjct: 1934 VDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEI 1993
Query: 391 XXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+G+ DG C D +EC C+ GTC N +GS+RC CPPG + S
Sbjct: 1994 GSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKS 2050
Score = 150 bits (363), Expect = 1e-35
Identities = 123/398 (30%), Positives = 170/398 (42%), Gaps = 47/398 (11%)
Query: 68 GFAPTAAGYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G P+ DV+EC + +C G+C+N++GSF+C C GY T CVD DEC
Sbjct: 2159 GTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI 2218
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFT---LSN--DGRTCLGLKLGWGVSCQACPAQGSELY 181
C NG C N GSF C C GF + N D C L + C GS Y
Sbjct: 2219 GNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCALRCMN--TFGS--Y 2274
Query: 182 AVLCPEGPS--KDNGGA-DINECTAVPGACPHGS--CENLEPGYRCICDPGY--HPDADG 234
CP G + +D D++EC C C+NL + CIC PG PD +G
Sbjct: 2275 ECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEG 2334
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
C D +EC C G+C N GS+ C C EG + C +D +G ++
Sbjct: 2335 -CVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTEC--LDNRQGLCFAEVLQ 2391
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQR---CLDNRRG 351
+ + T++E CD GR G+ +CEL L TAQ C
Sbjct: 2392 TICQMASSSRNLVTKSECC--CDGGR------GWGHQCEL-CPLPGTAQYKKICPHGPGY 2442
Query: 352 SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK-LDGATCR 410
+ R +D +C+ P L +C ++G G+ + G +C
Sbjct: 2443 TTDGRDID-ECKVM-PNLCTNGQCINTMG-----------SFRCFCKVGYTTDISGTSCI 2489
Query: 411 DVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
D+DEC+ S + C C NT+GSY+C CP G L G
Sbjct: 2490 DLDECSQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDG 2526
Score = 120 bits (288), Expect = 1e-26
Identities = 57/159 (35%), Positives = 77/159 (48%), Gaps = 3/159 (1%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
GIC+N G F C C+ G+ + G C DVDEC N R C+ G C+N G Y C C G+
Sbjct: 2585 GICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR-CQHG-CQNILGGYRCGCPQGY 2642
Query: 70 APTAA-GYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
C D +EC+ + C C N+ GS++C C +G+ AC DV+EC +
Sbjct: 2643 IQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSK 2702
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWG 167
N C NT G + C C PG+ G G+ G
Sbjct: 2703 NPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKG 2741
Score = 108 bits (260), Expect = 3e-23
Identities = 91/320 (28%), Positives = 125/320 (39%), Gaps = 24/320 (7%)
Query: 14 NIDGG-FECICKPGYESGSEGALCRDVDECRDN--PRVCRR-GRCRNTAGSYTCLCEPGF 69
N+ G F C PG+++ G C V CR++ C R C ++G + C
Sbjct: 87 NVCGSRFHSYCCPGWKTLPGGNQCI-VPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKS 145
Query: 70 APTAAGYCADVDECAADS-MCKGGRCVNSEGSFQCV--CEAGYRPTATRGACV---DVDE 123
+ C + CA D C+ G G C C+ G R A ACV +
Sbjct: 146 IQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIAQPCACVYGFTGPQ 205
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
CE R R G C + C+ + C WG C+ CPAQ
Sbjct: 206 CE--RDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATTGRAWGHPCEMCPAQPQPCRRG 263
Query: 184 LCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGY-HPDADGLCRDIDEC 242
P + D++EC A+PG C G+C N + C C G+ + C DIDEC
Sbjct: 264 FIPN--IRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDEC 321
Query: 243 DMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI 302
+ C G+C NT GS+ CVCP G + C ID+ T S G
Sbjct: 322 SIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRC--IDQ-----RTGMCFSGLVNGRC 374
Query: 303 PPTFPTR-TELASPCDNGRC 321
P R T++ C+ GRC
Sbjct: 375 AQELPGRMTKMQCCCEPGRC 394
Score = 73.7 bits (173), Expect = 1e-12
Identities = 43/130 (33%), Positives = 59/130 (45%), Gaps = 12/130 (9%)
Query: 316 CDNG-RCINTHGGFECECELGYVLDATAQRC-LDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
C NG RCI C C G+ T +C D R G C+ +V + C+ ++ +
Sbjct: 184 CQNGGRCIAQ----PCACVYGF----TGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTK 235
Query: 374 E-CCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCVNTD 431
CC + G AWG +GF + C+DVDEC +C GG C+NT
Sbjct: 236 TLCCATTGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTV 295
Query: 432 GSYRCDCPPG 441
GS+ C CP G
Sbjct: 296 GSFECRCPAG 305
Score = 64.5 bits (150), Expect = 7e-10
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
+N C + C N G ++C C G+ + C DV+EC + C G C NT G Y
Sbjct: 2658 SNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGY 2716
Query: 62 TCLCEPGFAPTAAGYC 77
C C PG+ G+C
Sbjct: 2717 LCGCPPGYYRVGQGHC 2732
Score = 48.0 bits (109), Expect = 7e-05
Identities = 18/41 (43%), Positives = 24/41 (58%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
C D+DEC++ +C G C NT GSY C CP G + G+
Sbjct: 315 CEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGS 355
Score = 43.2 bits (97), Expect = 0.002
Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 2/51 (3%)
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
G+ + C DVDEC ++ C G CVNT GSY C C G T A
Sbjct: 523 GYKQDANGDCIDVDEC--TSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQA 571
>Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein.
Length = 1821
Score = 273 bits (669), Expect = 1e-72
Identities = 164/466 (35%), Positives = 220/466 (47%), Gaps = 52/466 (11%)
Query: 10 GICKNIDGGFECICKPGYESGSEGAL--CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEP 67
G C N G + C C PGY + GA C+D++EC + P VC G+C NT GSY C C+
Sbjct: 900 GRCINRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQ 958
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCV-CEAGYRPTATRGACVDVDECEE 126
G+ G+C D++EC C GRCVNS GS+ C+ CE GYR G+CVDV+EC
Sbjct: 959 GYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLT 1016
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQA--CPAQGSELYAV 183
VC +G+C N GSFRC C G+ +++D + C + + SC C
Sbjct: 1017 PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACS 1076
Query: 184 LCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRC-ICDPGYHPDADG-LCRD 238
C G + G D++EC A PG CP G C N + C CD GY P G C D
Sbjct: 1077 ACENGYWVNEDGTACEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCED 1135
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE-THYIESDY 297
+DEC+ QS C GG+C+NT GS+ C+CP+G + +C D++EC GE + E
Sbjct: 1136 VDECEDPQSSCLGGECKNTVGSYQCLCPQGFQ-LANGTVCEDVNECMGEEHCAPHGECLN 1194
Query: 298 ERGDI----PPTFPTR---------TELAS--PCDNGRCINTHGGFECECELGYVLDATA 342
G P F + E A+ PC G C+NT G F C CE G+ +
Sbjct: 1195 SHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPES 1254
Query: 343 QRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA 402
C+D +D +CE + +C S G GF
Sbjct: 1255 GECVD----------ID-ECEDYGDPVCGTWKCENSPG---------SYRCVLGCQPGFH 1294
Query: 403 KLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
C D+DECA + G C NTDGS+RC C G + +G
Sbjct: 1295 MAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSG 1340
Score = 231 bits (564), Expect = 5e-60
Identities = 149/474 (31%), Positives = 208/474 (43%), Gaps = 60/474 (12%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCL 64
+C G C N+ G+ C+C PGY+ A C D +EC +P C+ +GRC N GSY+C
Sbjct: 855 VCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CQGKGRCINRVGSYSCF 912
Query: 65 CEPGFAPTAAG---YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG+ +G C D++EC +C GG+C N+EGS+ C C+ GY +G C D+
Sbjct: 913 CYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGY-IMVRKGHCQDI 971
Query: 122 DECEEQRVCRNGRCHNTPGSFRC-ECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
+EC C +GRC N+PGS+ C C G+ + + L GV
Sbjct: 972 NECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGS 1031
Query: 181 YAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYRC-ICDPGYHPDADG-L 235
+ C +G S + G D++EC A +CP G C N E + C C+ GY + DG
Sbjct: 1032 FRCSCEQGYEVTSDEKGCQDVDEC-ASRASCPTGLCLNTEGSFACSACENGYWVNEDGTA 1090
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCV-CPEGTRHEPELQLCRDIDECEGETETHYIE 294
C D+DEC C G C NTAGSF+C C G R P C D+DECE + ++ +
Sbjct: 1091 CEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECE-DPQSSCLG 1148
Query: 295 SDYER--GDIPPTFPTRTELA--SPCD-------------NGRCINTHGGFECECELGYV 337
+ + G P +LA + C+ +G C+N+HG F C C G+V
Sbjct: 1149 GECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFV 1208
Query: 338 LDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
C D + V G C C C G
Sbjct: 1209 SAEGGTSCQDVDECATTDPCVGGHCVNTEGSF----NCLCETGFQ--------------- 1249
Query: 398 XKGFAKLDGATCRDVDECA-LSAELCAGGTCVNTDGSYRC--DCPPGLTLDSTG 448
+ C D+DEC +C C N+ GSYRC C PG + G
Sbjct: 1250 ----PSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG 1299
Score = 225 bits (549), Expect = 3e-58
Identities = 148/451 (32%), Positives = 207/451 (45%), Gaps = 25/451 (5%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C+ G C N +G + C C GY +G C+D++ECR +P C GRC N+ GSYTCL
Sbjct: 938 GVCSGGQCTNTEGSYHCECDQGYIMVRKGH-CQDINECR-HPGTCPDGRCVNSPGSYTCL 995
Query: 65 -CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
CE G+ + G C DV+EC +C G+C N EGSF+C CE GY T+ C DVDE
Sbjct: 996 ACEEGYRGQS-GSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDE 1054
Query: 124 CEEQRVCRNGRCHNTPGSFRCE-CLPGFTLSNDGRTCLGL-KLGWGVSCQA--CPAQGSE 179
C + C G C NT GSF C C G+ ++ DG C L + + C + C
Sbjct: 1055 CASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGS 1114
Query: 180 LYAVLCPEG--PSK-DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
C G PS + D++EC +C G C+N Y+C+C G+ +C
Sbjct: 1115 FSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVC 1174
Query: 237 RDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIES 295
D++EC M + +CA G+C N+ GSF C+C G C+D+DEC
Sbjct: 1175 EDVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHC 1233
Query: 296 DYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGS--C 353
G T + SP ++G C++ ECE + G + T +C +N GS C
Sbjct: 1234 VNTEGSFNCLCETGFQ-PSP-ESGECVDID---ECE-DYGDPVCGT-WKC-ENSPGSYRC 1285
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGL-AWGSXXXXXXXXXXXXXKGF-AKLDGATCRD 411
G A + + EC + G +GF G C D
Sbjct: 1286 VLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVD 1345
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPGL 442
V+EC L +C C N +GS+ C C L
Sbjct: 1346 VNECELMLAVCGAALCENVEGSFLCLCASDL 1376
Score = 224 bits (548), Expect = 4e-58
Identities = 154/469 (32%), Positives = 204/469 (43%), Gaps = 35/469 (7%)
Query: 7 CTNGICKNIDGGFEC-ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL- 64
C G+C N +G F C C+ GY +G C D+DEC P VC G C NTAGS++C
Sbjct: 1061 CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTNTAGSFSCKD 1119
Query: 65 CEPGFAPTAAG-YCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+ G+ P+ G C DVDEC S C GG C N+ GS+QC+C G++ A C DV+
Sbjct: 1120 CDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQ-LANGTVCEDVN 1178
Query: 123 ECEEQRVCR-NGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSE- 179
EC + C +G C N+ GSF C C PGF + G +C + + C +E
Sbjct: 1179 ECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEG 1238
Query: 180 LYAVLCPEG--PSKDNGGA-DINECTAVPG-ACPHGSCENLEPGYRCI--CDPGYHPDAD 233
+ LC G PS ++G DI+EC C CEN YRC+ C PG+H +
Sbjct: 1239 SFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPN 1298
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G C DIDEC + G C NT GSF C+C +G P C D++ECE
Sbjct: 1299 GDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGA 1358
Query: 294 E-SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGS 352
+ G + E G C G + E A A +D G
Sbjct: 1359 ALCENVEGSFLCLCASDLE-EYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQ 1417
Query: 353 CWRRVVDGQCEAAAPELLLRQECCCSVGLAWG-------SXXXXXXXXXXXXXKGFAKLD 405
C + + ECCC+ G WG S KG+ ++
Sbjct: 1418 KGH----APCSSVLGRNTTQAECCCTQGATWGDACDLCPSEDSAEFSEICPSGKGYIPVE 1473
Query: 406 GATC------RDVDECALSAE-LCAGGTCVNTDGSYRCDCPPGLTLDST 447
GA D DEC + LC G C+NT Y C C PG D++
Sbjct: 1474 GAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDAS 1522
Score = 205 bits (501), Expect = 2e-52
Identities = 148/427 (34%), Positives = 189/427 (44%), Gaps = 71/427 (16%)
Query: 39 VDECRDNP-RVCRRGRCRNTAGSYTCLCEPGFA--PTAAGYCADVDECAADSMCKG-GRC 94
+D C VC G C N Y C+C PG+ P+ A YC D +EC D C+G GRC
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQA-YCTDDNECLRDP-CQGKGRC 902
Query: 95 VNSEGSFQCVCEAGYRPTATRGA---CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT 151
+N GS+ C C GY AT GA C D++ECE+ VC G+C NT GS+ CEC G+
Sbjct: 903 INRVGSYSCFCYPGYT-LATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYI 961
Query: 152 LSNDGRTCLGL-KLGWGVSCQ--ACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGA 207
+ G C + + +C C + C EG +G D+NEC PG
Sbjct: 962 MVRKGH-CQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLT-PGV 1019
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTC-VC 265
C HG C NLE +RC C+ GY +D C+D+DEC S C G C NT GSF C C
Sbjct: 1020 CAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRAS-CPTGLCLNTEGSFACSAC 1078
Query: 266 PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTH 325
G + C D+DEC FP C +G C NT
Sbjct: 1079 ENGYWVNEDGTACEDLDEC--------------------AFP------GVCPSGVCTNTA 1112
Query: 326 GGFEC-ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG 384
G F C +C+ GY C D VD +CE L EC +VG
Sbjct: 1113 GSFSCKDCDGGYRPSPLGDSCED----------VD-ECEDPQSSCL-GGECKNTVG---- 1156
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLT 443
+GF +G C DV+EC + E CA G C+N+ GS+ C C PG
Sbjct: 1157 -------SYQCLCPQGFQLANGTVCEDVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFV 1208
Query: 444 LDSTGTA 450
GT+
Sbjct: 1209 SAEGGTS 1215
Score = 204 bits (497), Expect = 7e-52
Identities = 131/388 (33%), Positives = 181/388 (46%), Gaps = 50/388 (12%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G CKN G ++C+C G++ + G +C DV+EC G C N+ GS+ CLC
Sbjct: 1146 CLGGECKNTVGSYQCLCPQGFQLAN-GTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCA 1204
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
PGF G C DVDECA C GG CVN+EGSF C+CE G++P+ G CVD+DECE
Sbjct: 1205 PGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECE 1264
Query: 126 E--QRVCRNGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGVSCQA---CP-AQ 176
+ VC +C N+PGS+RC C PGF ++ +G C+ + + C + C
Sbjct: 1265 DYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTD 1323
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCIC--DPGYHPD 231
GS + LC +G G D+NEC + C CEN+E + C+C D +
Sbjct: 1324 GS--FRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDA 1381
Query: 232 ADGLCR-------DIDECDM--H-----QSYCAGGQ-----CRNTAGSFT----CVCPEG 268
+G CR + E H + C GQ C + G T C C +G
Sbjct: 1382 QEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQG 1441
Query: 269 TRHEPELQLCRDIDECEGE----TETHYI--ESDYERGDIPPTFPTRTELASP--CDNGR 320
LC D E + YI E + G T + P C NGR
Sbjct: 1442 ATWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGR 1501
Query: 321 CINTHGGFECECELGYVLDATAQRCLDN 348
C+NT G+ C C G+ DA+ ++C D+
Sbjct: 1502 CLNTVPGYVCLCNPGFHYDASHKKCEDH 1529
Score = 186 bits (453), Expect = 1e-46
Identities = 127/417 (30%), Positives = 178/417 (42%), Gaps = 67/417 (16%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCL- 64
C G C N +G F C+C+ G++ E C D+DEC D VC +C N+ GSY C+
Sbjct: 1228 CVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVL 1287
Query: 65 -CEPGFAPTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+PGF G C D+DECA D+MC G C N++GSF+C+C+ G+ + + CVDV+
Sbjct: 1288 GCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVN 1347
Query: 123 ECEEQ-RVCRNGRCHNTPGSFRCECLPGFTL--SNDG----RTCLGLKLGWGVSCQACPA 175
ECE VC C N GSF C C + +G R G + + PA
Sbjct: 1348 ECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPA 1407
Query: 176 QGS-ELYAVLCPEGPSKDNGGADIN--ECTAVPGACPHGSCE------NLEPGYRCICDP 226
+ Y+ P G + EC GA +C+ + E C
Sbjct: 1408 PTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGATWGDACDLCPSEDSAEFSEICPSGK 1467
Query: 227 GYHPDADG------LCRDIDECDMH-QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR 279
GY P + D DEC + C G+C NT + C+C G ++ + C
Sbjct: 1468 GYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCE 1527
Query: 280 DIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLD 339
D DEC+ +LA C+NG C+NT G F C C LD
Sbjct: 1528 DHDECQ-------------------------DLA--CENGECVNTEGSFHCFCSPPLTLD 1560
Query: 340 ATAQRCLDNRRGS------------CWRRVVDGQC-EAAAPELLLRQECCCSVGLAW 383
+ QRC+++ + CW++V + C E ECCC G AW
Sbjct: 1561 LSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGKAW 1617
Score = 175 bits (427), Expect = 2e-43
Identities = 131/409 (32%), Positives = 170/409 (41%), Gaps = 53/409 (12%)
Query: 80 VDECAADS--MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN 137
+D CAA + +C G CVN ++CVC GY+ ++ C D +EC GRC N
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCQGKGRCIN 904
Query: 138 TPGSFRCECLPGFTLSNDGRT--CLGL----KLGWGVSCQACPAQGSELYAVLCPEGPSK 191
GS+ C C PG+TL+ G T C + + G Q +GS Y C +G
Sbjct: 905 RVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGS--YHCECDQGYIM 962
Query: 192 DNGG--ADINECTAVPGACPHGSCENLEPGYRCI-CDPGYHPDADGLCRDIDECDMHQSY 248
G DINEC PG CP G C N Y C+ C+ GY + G C D++EC +
Sbjct: 963 VRKGHCQDINECRH-PGTCPDGRCVNSPGSYTCLACEEGYRGQS-GSCVDVNEC-LTPGV 1019
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC--------------EGETETHYIE 294
CA G+C N GSF C C +G + + C+D+DEC EG E
Sbjct: 1020 CAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACE 1079
Query: 295 SDYERGDIPPTFPTRTELASP--CDNGRCINTHGGFEC-ECELGYVLDATAQRCLDNRR- 350
+ Y + E A P C +G C NT G F C +C+ GY C D
Sbjct: 1080 NGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDEC 1139
Query: 351 ---------GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSX--------XXXXXXX 393
G C V QC L C V G
Sbjct: 1140 EDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSF 1199
Query: 394 XXXXXKGFAKLDGAT-CRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF +G T C+DVDECA + + C GG CVNT+GS+ C C G
Sbjct: 1200 FCLCAPGFVSAEGGTSCQDVDECA-TTDPCVGGHCVNTEGSFNCLCETG 1247
Score = 157 bits (381), Expect = 8e-38
Identities = 100/319 (31%), Positives = 140/319 (43%), Gaps = 32/319 (10%)
Query: 6 MCTNGICKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
+C C+N G + C+ C+PG+ G C D+DEC ++ G C NT GS+ C
Sbjct: 1270 VCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDECANDTMCGSHGFCDNTDGSFRC 1328
Query: 64 LCEPGFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVC----------EAGYRP 111
LC+ GF + +G+ C DV+EC ++C C N EGSF C+C E RP
Sbjct: 1329 LCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRP 1388
Query: 112 TATRGACV-DVDECEEQRVCRNGRCHN-TPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS 169
G + + + C++ G C + G + C WG +
Sbjct: 1389 RGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRN-TTQAECCCTQGATWGDA 1447
Query: 170 CQACPAQGSELYAVLCPEGPSK-DNGGA---------DINECTAV-PGACPHGSCENLEP 218
C CP++ S ++ +CP G GA D +EC PG CP+G C N P
Sbjct: 1448 CDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVP 1507
Query: 219 GYRCICDPGYHPDAD-GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL 277
GY C+C+PG+H DA C D DEC C G+C NT GSF C C + Q
Sbjct: 1508 GYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLTLDLSQQR 1565
Query: 278 CRDIDECEGETETHYIESD 296
C + + H I D
Sbjct: 1566 CMNSTSSTEDLPDHDIHMD 1584
Score = 88.6 bits (210), Expect = 4e-17
Identities = 134/500 (26%), Positives = 184/500 (36%), Gaps = 93/500 (18%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C + C N G + C C+PG + C D +G C + G TC
Sbjct: 630 GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC-----VSDKAISMLQGLCYRSLGPGTCT 684
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPT-ATRGACVDVDE 123
T C A S C+ +E +F+ +C AG+ T A+ + + +
Sbjct: 685 LPLAQRITKQICCCSRVGKAWGSECEKCPLPGTE-AFREICPAGHGYTYASSDIRLSMRK 743
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-----SCQACPAQGS 178
EE+ + R R G LPG R L G QA S
Sbjct: 744 AEEEELARPPR---EQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTS 800
Query: 179 ELYAVLCPEG-----PSKDNGGADINE-----------CTAVPG--ACPHGSCENLEPG- 219
+A G P + G A+I E + PG C G+ PG
Sbjct: 801 VTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGT 860
Query: 220 -------YRCICDPGY--HPDADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEG- 268
YRC+C PGY HP + C D +EC + C G G+C N GS++C C G
Sbjct: 861 CVNLPDGYRCVCSPGYQLHP-SQAYCTDDNEC--LRDPCQGKGRCINRVGSYSCFCYPGY 917
Query: 269 -TRHEPELQLCRDIDECE-------GE---TETHYIESDYERGDI---PPTFPTRTELAS 314
Q C+DI+ECE G+ TE Y + ++G I E
Sbjct: 918 TLATSGATQECQDINECEQPGVCSGGQCTNTEGSY-HCECDQGYIMVRKGHCQDINECRH 976
Query: 315 P--CDNGRCINTHGGFEC-ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLL 371
P C +GRC+N+ G + C CE GY + C+D G+C
Sbjct: 977 PGTCPDGRCVNSPGSYTCLACEEGY--RGQSGSCVDVNECLTPGVCAHGKCTNLEGSF-- 1032
Query: 372 RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTD 431
C C G S D C+DVDECA A C G C+NT+
Sbjct: 1033 --RCSCEQGYEVTS-------------------DEKGCQDVDECASRAS-CPTGLCLNTE 1070
Query: 432 GSYRCD-CPPGLTLDSTGTA 450
GS+ C C G ++ GTA
Sbjct: 1071 GSFACSACENGYWVNEDGTA 1090
Score = 87.0 bits (206), Expect = 1e-16
Identities = 55/154 (35%), Positives = 67/154 (43%), Gaps = 8/154 (5%)
Query: 38 DVDECRD-NPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRCV 95
D DEC P +C GRC NT Y CLC PGF A+ C D DEC D C+ G CV
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ-DLACENGECV 1543
Query: 96 NSEGSFQCVCEAGYRPTATRGACVDVDECEE---QRVCRNGRCHNTPGSFRC-ECLPGFT 151
N+EGSF C C ++ C++ E C + C E L G
Sbjct: 1544 NTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHR 1603
Query: 152 LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
+ C K W C CP + SE+YA LC
Sbjct: 1604 TTYTECCCQDGK-AWSQQCALCPPRSSEVYAQLC 1636
Score = 75.8 bits (178), Expect = 3e-13
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 4/134 (2%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ +C D++EC +CK CVN+ GS+ C C G +R CV
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS---- 663
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
++ G C+ + G C ++ C + WG C+ CP G+E + +
Sbjct: 664 DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREI 723
Query: 185 CPEGPSKDNGGADI 198
CP G +DI
Sbjct: 724 CPAGHGYTYASSDI 737
Score = 71.7 bits (168), Expect = 5e-12
Identities = 32/84 (38%), Positives = 45/84 (53%), Gaps = 4/84 (4%)
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR-- 128
P A +EC + C+ GRCV + C C G++ A ACVDV+EC++
Sbjct: 1725 PPAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGP 1784
Query: 129 --VCRNGRCHNTPGSFRCECLPGF 150
+C +G C NT GS+RC C PG+
Sbjct: 1785 AVLCVHGYCENTEGSYRCHCSPGY 1808
Score = 70.5 bits (165), Expect = 1e-11
Identities = 38/105 (36%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG----------SXXXXXXXXXXXXXKG 400
G C+ V+GQC EL +++CC SVG WG +G
Sbjct: 552 GRCYLNTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQG 611
Query: 401 FAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
+ +L+ C+D++EC L+ LC CVNT GSY C C PGL LD
Sbjct: 612 YKRLNLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLD 655
Score = 68.1 bits (159), Expect = 6e-11
Identities = 27/63 (42%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C NG C N G+ C+C PG+ + C D DEC+D C G C NT GS+ C
Sbjct: 1495 GLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQD--LACENGECVNTEGSFHCF 1552
Query: 65 CEP 67
C P
Sbjct: 1553 CSP 1555
Score = 62.5 bits (145), Expect = 3e-09
Identities = 29/70 (41%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD--NPRV-CRRGRCRNTAGSYTC 63
C NG C + G+ C C G++ + C DV+EC D P V C G C NT GSY C
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 64 LCEPGFAPTA 73
C PG+ A
Sbjct: 1803 HCSPGYVAEA 1812
Score = 61.7 bits (143), Expect = 5e-09
Identities = 38/102 (37%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 174 PAQGSEL---YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
P Q SEL Y PE P+ G EC + G C +G C + GY C C G+
Sbjct: 1708 PLQPSELQPHYVASHPEPPAGFEG-LQAEECGILNG-CENGRCVRVREGYTCDCFEGFQL 1765
Query: 231 DADGL-CRDIDECDMHQS---YCAGGQCRNTAGSFTCVCPEG 268
DA + C D++ECD C G C NT GS+ C C G
Sbjct: 1766 DAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPG 1807
Score = 56.0 bits (129), Expect = 3e-07
Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
Query: 49 CRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDEC----AADSMCKGGRCVNSEGSFQC 103
C GRC YTC C GF AA C DV+EC +C G C N+EGS++C
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 104 VCEAGY 109
C GY
Sbjct: 1803 HCSPGY 1808
Score = 51.6 bits (118), Expect = 6e-06
Identities = 45/162 (27%), Positives = 63/162 (38%), Gaps = 15/162 (9%)
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQACPAQGS----ELYAVLCPE 187
GRC+ + +C P L+ C + WGV+ C CP + + E + CP+
Sbjct: 552 GRCYLNTVNGQC-ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQ 610
Query: 188 GPSKDN--GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLCRDIDECDM 244
G + N DINEC + G C C N Y C C PG D + C M
Sbjct: 611 GYKRLNLTHCQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISM 669
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG 286
Q G C + G TC P R ++ C + + G
Sbjct: 670 LQ-----GLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWG 706
Score = 46.8 bits (106), Expect = 2e-04
Identities = 21/37 (56%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
C D DEC A C G CVNT+GS+ C C P LTLD
Sbjct: 1526 CEDHDECQDLA--CENGECVNTEGSFHCFCSPPLTLD 1560
Score = 46.4 bits (105), Expect = 2e-04
Identities = 20/39 (51%), Positives = 23/39 (58%), Gaps = 3/39 (7%)
Query: 197 DINECTAVPGA---CPHGSCENLEPGYRCICDPGYHPDA 232
D+NEC + G C HG CEN E YRC C PGY +A
Sbjct: 1774 DVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEA 1812
Score = 45.6 bits (103), Expect = 4e-04
Identities = 26/53 (49%), Positives = 33/53 (62%), Gaps = 6/53 (11%)
Query: 399 KGFAKLDGA--TCRDVDECA-LS--AELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+GF +LD A C DV+EC L+ A LC G C NT+GSYRC C PG ++
Sbjct: 1761 EGF-QLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEA 1812
Score = 42.3 bits (95), Expect = 0.003
Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Query: 287 ETETHYIESDYER-GDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
E + HY+ S E + + C+NGRC+ G+ C+C G+ LDA C
Sbjct: 1713 ELQPHYVASHPEPPAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMAC 1772
Query: 346 LD 347
+D
Sbjct: 1773 VD 1774
Score = 41.5 bits (93), Expect = 0.006
Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 13/98 (13%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA--PTAAGYCADVDECAADSMCKGGR 93
C+D++EC +C+ C NT GSY C C PG P+ + +D A SM + G
Sbjct: 620 CQDINECL-TLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD----KAISMLQ-GL 673
Query: 94 CVNSEGSFQCVCEAGYRPTATRGACVDV-----DECEE 126
C S G C R T C V ECE+
Sbjct: 674 CYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEK 711
Score = 41.5 bits (93), Expect = 0.006
Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 23/106 (21%)
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYER 299
+EC + C G+C +TC C EG + + C D++EC+
Sbjct: 1735 EECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECD-------------- 1779
Query: 300 GDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
D+ A C +G C NT G + C C GYV +A C
Sbjct: 1780 -DLNGP-------AVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 35.5 bits (78), Expect = 0.39
Identities = 10/22 (45%), Positives = 15/22 (68%)
Query: 6 MCTNGICKNIDGGFECICKPGY 27
+C +G C+N +G + C C PGY
Sbjct: 1787 LCVHGYCENTEGSYRCHCSPGY 1808
Score = 33.9 bits (74), Expect = 1.2
Identities = 13/42 (30%), Positives = 18/42 (42%)
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
+ +EC C NGRC + C+C GF L C+
Sbjct: 1732 LQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACV 1773
>S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growth
factor-beta-binding protein-2 protein.
Length = 1821
Score = 273 bits (669), Expect = 1e-72
Identities = 164/466 (35%), Positives = 220/466 (47%), Gaps = 52/466 (11%)
Query: 10 GICKNIDGGFECICKPGYESGSEGAL--CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEP 67
G C N G + C C PGY + GA C+D++EC + P VC G+C NT GSY C C+
Sbjct: 900 GRCINRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQ 958
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCV-CEAGYRPTATRGACVDVDECEE 126
G+ G+C D++EC C GRCVNS GS+ C+ CE GYR G+CVDV+EC
Sbjct: 959 GYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLT 1016
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQA--CPAQGSELYAV 183
VC +G+C N GSFRC C G+ +++D + C + + SC C
Sbjct: 1017 PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACS 1076
Query: 184 LCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRC-ICDPGYHPDADG-LCRD 238
C G + G D++EC A PG CP G C N + C CD GY P G C D
Sbjct: 1077 ACENGYWVNEDGTACEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCED 1135
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE-THYIESDY 297
+DEC+ QS C GG+C+NT GS+ C+CP+G + +C D++EC GE + E
Sbjct: 1136 VDECEDPQSSCLGGECKNTVGSYQCLCPQGFQ-LANGTVCEDVNECMGEEHCAPHGECLN 1194
Query: 298 ERGDI----PPTFPTR---------TELAS--PCDNGRCINTHGGFECECELGYVLDATA 342
G P F + E A+ PC G C+NT G F C CE G+ +
Sbjct: 1195 SHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPES 1254
Query: 343 QRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA 402
C+D +D +CE + +C S G GF
Sbjct: 1255 GECVD----------ID-ECEDYGDPVCGTWKCENSPG---------SYRCVLGCQPGFH 1294
Query: 403 KLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
C D+DECA + G C NTDGS+RC C G + +G
Sbjct: 1295 MAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSG 1340
Score = 231 bits (565), Expect = 4e-60
Identities = 149/474 (31%), Positives = 208/474 (43%), Gaps = 60/474 (12%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCL 64
+C G C N+ G+ C+C PGY+ A C D +EC +P C+ +GRC N GSY+C
Sbjct: 855 VCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CKGKGRCINRVGSYSCF 912
Query: 65 CEPGFAPTAAG---YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG+ +G C D++EC +C GG+C N+EGS+ C C+ GY +G C D+
Sbjct: 913 CYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGY-IMVRKGHCQDI 971
Query: 122 DECEEQRVCRNGRCHNTPGSFRC-ECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
+EC C +GRC N+PGS+ C C G+ + + L GV
Sbjct: 972 NECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGS 1031
Query: 181 YAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYRC-ICDPGYHPDADG-L 235
+ C +G S + G D++EC A +CP G C N E + C C+ GY + DG
Sbjct: 1032 FRCSCEQGYEVTSDEKGCQDVDEC-ASRASCPTGLCLNTEGSFACSACENGYWVNEDGTA 1090
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCV-CPEGTRHEPELQLCRDIDECEGETETHYIE 294
C D+DEC C G C NTAGSF+C C G R P C D+DECE + ++ +
Sbjct: 1091 CEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECE-DPQSSCLG 1148
Query: 295 SDYER--GDIPPTFPTRTELA--SPCD-------------NGRCINTHGGFECECELGYV 337
+ + G P +LA + C+ +G C+N+HG F C C G+V
Sbjct: 1149 GECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFV 1208
Query: 338 LDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
C D + V G C C C G
Sbjct: 1209 SAEGGTSCQDVDECATTDPCVGGHCVNTEGSF----NCLCETGFQ--------------- 1249
Query: 398 XKGFAKLDGATCRDVDECA-LSAELCAGGTCVNTDGSYRC--DCPPGLTLDSTG 448
+ C D+DEC +C C N+ GSYRC C PG + G
Sbjct: 1250 ----PSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG 1299
Score = 225 bits (549), Expect = 3e-58
Identities = 148/451 (32%), Positives = 207/451 (45%), Gaps = 25/451 (5%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C+ G C N +G + C C GY +G C+D++ECR +P C GRC N+ GSYTCL
Sbjct: 938 GVCSGGQCTNTEGSYHCECDQGYIMVRKGH-CQDINECR-HPGTCPDGRCVNSPGSYTCL 995
Query: 65 -CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
CE G+ + G C DV+EC +C G+C N EGSF+C CE GY T+ C DVDE
Sbjct: 996 ACEEGYRGQS-GSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDE 1054
Query: 124 CEEQRVCRNGRCHNTPGSFRCE-CLPGFTLSNDGRTCLGL-KLGWGVSCQA--CPAQGSE 179
C + C G C NT GSF C C G+ ++ DG C L + + C + C
Sbjct: 1055 CASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGS 1114
Query: 180 LYAVLCPEG--PSK-DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
C G PS + D++EC +C G C+N Y+C+C G+ +C
Sbjct: 1115 FSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVC 1174
Query: 237 RDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIES 295
D++EC M + +CA G+C N+ GSF C+C G C+D+DEC
Sbjct: 1175 EDVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHC 1233
Query: 296 DYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGS--C 353
G T + SP ++G C++ ECE + G + T +C +N GS C
Sbjct: 1234 VNTEGSFNCLCETGFQ-PSP-ESGECVDID---ECE-DYGDPVCGT-WKC-ENSPGSYRC 1285
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGL-AWGSXXXXXXXXXXXXXKGF-AKLDGATCRD 411
G A + + EC + G +GF G C D
Sbjct: 1286 VLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVD 1345
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPGL 442
V+EC L +C C N +GS+ C C L
Sbjct: 1346 VNECELMLAVCGAALCENVEGSFLCLCASDL 1376
Score = 225 bits (549), Expect = 3e-58
Identities = 154/469 (32%), Positives = 205/469 (43%), Gaps = 35/469 (7%)
Query: 7 CTNGICKNIDGGFEC-ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL- 64
C G+C N +G F C C+ GY +G C D+DEC P VC G C NTAGS++C
Sbjct: 1061 CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTNTAGSFSCKD 1119
Query: 65 CEPGFAPTAAG-YCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+ G+ P+ G C DVDEC S C GG C N+ GS+QC+C G++ A C DV+
Sbjct: 1120 CDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQ-LANGTVCEDVN 1178
Query: 123 ECEEQRVCR-NGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSE- 179
EC + C +G C N+ GSF C C PGF + G +C + + C +E
Sbjct: 1179 ECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEG 1238
Query: 180 LYAVLCPEG--PSKDNGGA-DINECTAVPG-ACPHGSCENLEPGYRCI--CDPGYHPDAD 233
+ LC G PS ++G DI+EC C CEN YRC+ C PG+H +
Sbjct: 1239 SFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPN 1298
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G C DIDEC + G C NT GSF C+C +G P C D++ECE
Sbjct: 1299 GDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGA 1358
Query: 294 E-SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGS 352
+ G + E G C G + E A A +D G
Sbjct: 1359 ALCENVEGSFLCLCASDLE-EYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQ 1417
Query: 353 CWRRVVDGQCEAAAPELLLRQECCCSVGLAWG-------SXXXXXXXXXXXXXKGFAKLD 405
C + + ECCC+ G +WG S KG+ ++
Sbjct: 1418 KGH----APCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVE 1473
Query: 406 GATC------RDVDECALSAE-LCAGGTCVNTDGSYRCDCPPGLTLDST 447
GA D DEC + LC G C+NT Y C C PG D++
Sbjct: 1474 GAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDAS 1522
Score = 207 bits (505), Expect = 7e-53
Identities = 149/427 (34%), Positives = 189/427 (44%), Gaps = 71/427 (16%)
Query: 39 VDECRDNP-RVCRRGRCRNTAGSYTCLCEPGFA--PTAAGYCADVDECAADSMCKG-GRC 94
+D C VC G C N Y C+C PG+ P+ A YC D +EC D CKG GRC
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQA-YCTDDNECLRDP-CKGKGRC 902
Query: 95 VNSEGSFQCVCEAGYRPTATRGA---CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT 151
+N GS+ C C GY AT GA C D++ECE+ VC G+C NT GS+ CEC G+
Sbjct: 903 INRVGSYSCFCYPGYT-LATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYI 961
Query: 152 LSNDGRTCLGL-KLGWGVSCQ--ACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGA 207
+ G C + + +C C + C EG +G D+NEC PG
Sbjct: 962 MVRKGH-CQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLT-PGV 1019
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTC-VC 265
C HG C NLE +RC C+ GY +D C+D+DEC S C G C NT GSF C C
Sbjct: 1020 CAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRAS-CPTGLCLNTEGSFACSAC 1078
Query: 266 PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTH 325
G + C D+DEC FP C +G C NT
Sbjct: 1079 ENGYWVNEDGTACEDLDEC--------------------AFP------GVCPSGVCTNTA 1112
Query: 326 GGFEC-ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG 384
G F C +C+ GY C D VD +CE L EC +VG
Sbjct: 1113 GSFSCKDCDGGYRPSPLGDSCED----------VD-ECEDPQSSCL-GGECKNTVG---- 1156
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLT 443
+GF +G C DV+EC + E CA G C+N+ GS+ C C PG
Sbjct: 1157 -------SYQCLCPQGFQLANGTVCEDVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFV 1208
Query: 444 LDSTGTA 450
GT+
Sbjct: 1209 SAEGGTS 1215
Score = 204 bits (497), Expect = 7e-52
Identities = 131/388 (33%), Positives = 181/388 (46%), Gaps = 50/388 (12%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G CKN G ++C+C G++ + G +C DV+EC G C N+ GS+ CLC
Sbjct: 1146 CLGGECKNTVGSYQCLCPQGFQLAN-GTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCA 1204
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
PGF G C DVDECA C GG CVN+EGSF C+CE G++P+ G CVD+DECE
Sbjct: 1205 PGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECE 1264
Query: 126 E--QRVCRNGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGVSCQA---CP-AQ 176
+ VC +C N+PGS+RC C PGF ++ +G C+ + + C + C
Sbjct: 1265 DYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTD 1323
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCIC--DPGYHPD 231
GS + LC +G G D+NEC + C CEN+E + C+C D +
Sbjct: 1324 GS--FRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDA 1381
Query: 232 ADGLCR-------DIDECDM--H-----QSYCAGGQ-----CRNTAGSFT----CVCPEG 268
+G CR + E H + C GQ C + G T C C +G
Sbjct: 1382 QEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQG 1441
Query: 269 TRHEPELQLCRDIDECEGE----TETHYI--ESDYERGDIPPTFPTRTELASP--CDNGR 320
LC D E + YI E + G T + P C NGR
Sbjct: 1442 ASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGR 1501
Query: 321 CINTHGGFECECELGYVLDATAQRCLDN 348
C+NT G+ C C G+ DA+ ++C D+
Sbjct: 1502 CLNTVPGYVCLCNPGFHYDASHKKCEDH 1529
Score = 186 bits (452), Expect = 2e-46
Identities = 127/417 (30%), Positives = 178/417 (42%), Gaps = 67/417 (16%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCL- 64
C G C N +G F C+C+ G++ E C D+DEC D VC +C N+ GSY C+
Sbjct: 1228 CVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVL 1287
Query: 65 -CEPGFAPTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+PGF G C D+DECA D+MC G C N++GSF+C+C+ G+ + + CVDV+
Sbjct: 1288 GCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVN 1347
Query: 123 ECEEQ-RVCRNGRCHNTPGSFRCECLPGFTL--SNDG----RTCLGLKLGWGVSCQACPA 175
ECE VC C N GSF C C + +G R G + + PA
Sbjct: 1348 ECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPA 1407
Query: 176 QGS-ELYAVLCPEGPSKDNGGADIN--ECTAVPGACPHGSCE------NLEPGYRCICDP 226
+ Y+ P G + EC GA +C+ + E C
Sbjct: 1408 PTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGK 1467
Query: 227 GYHPDADG------LCRDIDECDMH-QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR 279
GY P + D DEC + C G+C NT + C+C G ++ + C
Sbjct: 1468 GYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCE 1527
Query: 280 DIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLD 339
D DEC+ +LA C+NG C+NT G F C C LD
Sbjct: 1528 DHDECQ-------------------------DLA--CENGECVNTEGSFHCFCSPPLTLD 1560
Query: 340 ATAQRCLDNRRGS------------CWRRVVDGQC-EAAAPELLLRQECCCSVGLAW 383
+ QRC+++ + CW++V + C E ECCC G AW
Sbjct: 1561 LSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAW 1617
Score = 175 bits (427), Expect = 2e-43
Identities = 131/409 (32%), Positives = 170/409 (41%), Gaps = 53/409 (12%)
Query: 80 VDECAADS--MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN 137
+D CAA + +C G CVN ++CVC GY+ ++ C D +EC GRC N
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 904
Query: 138 TPGSFRCECLPGFTLSNDGRT--CLGL----KLGWGVSCQACPAQGSELYAVLCPEGPSK 191
GS+ C C PG+TL+ G T C + + G Q +GS Y C +G
Sbjct: 905 RVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGS--YHCECDQGYIM 962
Query: 192 DNGG--ADINECTAVPGACPHGSCENLEPGYRCI-CDPGYHPDADGLCRDIDECDMHQSY 248
G DINEC PG CP G C N Y C+ C+ GY + G C D++EC +
Sbjct: 963 VRKGHCQDINECRH-PGTCPDGRCVNSPGSYTCLACEEGYRGQS-GSCVDVNEC-LTPGV 1019
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC--------------EGETETHYIE 294
CA G+C N GSF C C +G + + C+D+DEC EG E
Sbjct: 1020 CAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACE 1079
Query: 295 SDYERGDIPPTFPTRTELASP--CDNGRCINTHGGFEC-ECELGYVLDATAQRCLDNRR- 350
+ Y + E A P C +G C NT G F C +C+ GY C D
Sbjct: 1080 NGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDEC 1139
Query: 351 ---------GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSX--------XXXXXXX 393
G C V QC L C V G
Sbjct: 1140 EDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSF 1199
Query: 394 XXXXXKGFAKLDGAT-CRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF +G T C+DVDECA + + C GG CVNT+GS+ C C G
Sbjct: 1200 FCLCAPGFVSAEGGTSCQDVDECA-TTDPCVGGHCVNTEGSFNCLCETG 1247
Score = 158 bits (383), Expect = 4e-38
Identities = 100/319 (31%), Positives = 140/319 (43%), Gaps = 32/319 (10%)
Query: 6 MCTNGICKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
+C C+N G + C+ C+PG+ G C D+DEC ++ G C NT GS+ C
Sbjct: 1270 VCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDECANDTMCGSHGFCDNTDGSFRC 1328
Query: 64 LCEPGFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVC----------EAGYRP 111
LC+ GF + +G+ C DV+EC ++C C N EGSF C+C E RP
Sbjct: 1329 LCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRP 1388
Query: 112 TATRGACV-DVDECEEQRVCRNGRCHN-TPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS 169
G + + + C++ G C + G + C WG +
Sbjct: 1389 RGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRN-TTQAECCCTQGASWGDA 1447
Query: 170 CQACPAQGSELYAVLCPEGPSK-DNGGA---------DINECTAV-PGACPHGSCENLEP 218
C CP++ S ++ +CP G GA D +EC PG CP+G C N P
Sbjct: 1448 CDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVP 1507
Query: 219 GYRCICDPGYHPDAD-GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL 277
GY C+C+PG+H DA C D DEC C G+C NT GSF C C + Q
Sbjct: 1508 GYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLTLDLSQQR 1565
Query: 278 CRDIDECEGETETHYIESD 296
C + + H I D
Sbjct: 1566 CMNSTSSTEDLPDHDIHMD 1584
Score = 88.6 bits (210), Expect = 4e-17
Identities = 134/500 (26%), Positives = 184/500 (36%), Gaps = 93/500 (18%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C + C N G + C C+PG + C D +G C + G TC
Sbjct: 630 GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC-----VSDKAISMLQGLCYRSLGPGTCT 684
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPT-ATRGACVDVDE 123
T C A S C+ +E +F+ +C AG+ T A+ + + +
Sbjct: 685 LPLAQRITKQICCCSRVGKAWGSECEKCPLPGTE-AFREICPAGHGYTYASSDIRLSMRK 743
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-----SCQACPAQGS 178
EE+ + R R G LPG R L G QA S
Sbjct: 744 AEEEELARPPR---EQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTS 800
Query: 179 ELYAVLCPEG-----PSKDNGGADINE-----------CTAVPG--ACPHGSCENLEPG- 219
+A G P + G A+I E + PG C G+ PG
Sbjct: 801 VTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGT 860
Query: 220 -------YRCICDPGY--HPDADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEG- 268
YRC+C PGY HP + C D +EC + C G G+C N GS++C C G
Sbjct: 861 CVNLPDGYRCVCSPGYQLHP-SQAYCTDDNEC--LRDPCKGKGRCINRVGSYSCFCYPGY 917
Query: 269 -TRHEPELQLCRDIDECE-------GE---TETHYIESDYERGDI---PPTFPTRTELAS 314
Q C+DI+ECE G+ TE Y + ++G I E
Sbjct: 918 TLATSGATQECQDINECEQPGVCSGGQCTNTEGSY-HCECDQGYIMVRKGHCQDINECRH 976
Query: 315 P--CDNGRCINTHGGFEC-ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLL 371
P C +GRC+N+ G + C CE GY + C+D G+C
Sbjct: 977 PGTCPDGRCVNSPGSYTCLACEEGY--RGQSGSCVDVNECLTPGVCAHGKCTNLEGSF-- 1032
Query: 372 RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTD 431
C C G S D C+DVDECA A C G C+NT+
Sbjct: 1033 --RCSCEQGYEVTS-------------------DEKGCQDVDECASRAS-CPTGLCLNTE 1070
Query: 432 GSYRCD-CPPGLTLDSTGTA 450
GS+ C C G ++ GTA
Sbjct: 1071 GSFACSACENGYWVNEDGTA 1090
Score = 75.8 bits (178), Expect = 3e-13
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 4/134 (2%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ +C D++EC +CK CVN+ GS+ C C G +R CV
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS---- 663
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
++ G C+ + G C ++ C + WG C+ CP G+E + +
Sbjct: 664 DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREI 723
Query: 185 CPEGPSKDNGGADI 198
CP G +DI
Sbjct: 724 CPAGHGYTYASSDI 737
Score = 71.7 bits (168), Expect = 5e-12
Identities = 32/84 (38%), Positives = 45/84 (53%), Gaps = 4/84 (4%)
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR-- 128
P A +EC + C+ GRCV + C C G++ A ACVDV+EC++
Sbjct: 1725 PPAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGP 1784
Query: 129 --VCRNGRCHNTPGSFRCECLPGF 150
+C +G C NT GS+RC C PG+
Sbjct: 1785 AVLCVHGYCENTEGSYRCHCSPGY 1808
Score = 70.5 bits (165), Expect = 1e-11
Identities = 38/105 (36%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG----------SXXXXXXXXXXXXXKG 400
G C+ V+GQC EL +++CC SVG WG +G
Sbjct: 552 GRCYLNTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQG 611
Query: 401 FAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
+ +L+ C+D++EC L+ LC CVNT GSY C C PGL LD
Sbjct: 612 YKRLNLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLD 655
Score = 68.1 bits (159), Expect = 6e-11
Identities = 27/63 (42%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C NG C N G+ C+C PG+ + C D DEC+D C G C NT GS+ C
Sbjct: 1495 GLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQD--LACENGECVNTEGSFHCF 1552
Query: 65 CEP 67
C P
Sbjct: 1553 CSP 1555
Score = 62.5 bits (145), Expect = 3e-09
Identities = 29/70 (41%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD--NPRV-CRRGRCRNTAGSYTC 63
C NG C + G+ C C G++ + C DV+EC D P V C G C NT GSY C
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 64 LCEPGFAPTA 73
C PG+ A
Sbjct: 1803 HCSPGYVAEA 1812
Score = 61.7 bits (143), Expect = 5e-09
Identities = 38/102 (37%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 174 PAQGSEL---YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
P Q SEL Y PE P+ G EC + G C +G C + GY C C G+
Sbjct: 1708 PLQPSELQPHYVASHPEPPAGFEG-LQAEECGILNG-CENGRCVRVREGYTCDCFEGFQL 1765
Query: 231 DADGL-CRDIDECDMHQS---YCAGGQCRNTAGSFTCVCPEG 268
DA + C D++ECD C G C NT GS+ C C G
Sbjct: 1766 DAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPG 1807
Score = 60.1 bits (139), Expect = 2e-08
Identities = 78/320 (24%), Positives = 108/320 (33%), Gaps = 40/320 (12%)
Query: 38 DVDECRD-NPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVN 96
D DEC P +C GRC NT Y CLC PGF Y A +C C+ C N
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFH-----YDASHKKCEDHDECQDLACEN 1539
Query: 97 SEGSFQCV-CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSND 155
E CV E + + +D+ + RC N+ S E LP + D
Sbjct: 1540 GE----CVNTEGSFHCFCSPPLTLDLSQ---------QRCMNSTSS--TEDLPDHDIHMD 1584
Query: 156 -------GRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGAC 208
C G + C Q E ++ C P + + C
Sbjct: 1585 ICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSE-VYAQLCNVARIEA 1643
Query: 209 PHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
+ + PGY Y P D L I D Y G +T P
Sbjct: 1644 EREAGVHFRPGYE------YGPGPDDLHYSIYGPDGAPFYNYLGP-EDTVPE--PAFPNT 1694
Query: 269 TRHEPELQLCRDIDECEGETETHYIESDYER-GDIPPTFPTRTELASPCDNGRCINTHGG 327
H + + E + HY+ S E + + C+NGRC+ G
Sbjct: 1695 AGHSADRTPILESPLQPSELQPHYVASHPEPPAGFEGLQAEECGILNGCENGRCVRVREG 1754
Query: 328 FECECELGYVLDATAQRCLD 347
+ C+C G+ LDA C+D
Sbjct: 1755 YTCDCFEGFQLDAAHMACVD 1774
Score = 56.0 bits (129), Expect = 3e-07
Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
Query: 49 CRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDEC----AADSMCKGGRCVNSEGSFQC 103
C GRC YTC C GF AA C DV+EC +C G C N+EGS++C
Sbjct: 1743 CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC 1802
Query: 104 VCEAGY 109
C GY
Sbjct: 1803 HCSPGY 1808
Score = 51.6 bits (118), Expect = 6e-06
Identities = 45/162 (27%), Positives = 63/162 (38%), Gaps = 15/162 (9%)
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQACPAQGS----ELYAVLCPE 187
GRC+ + +C P L+ C + WGV+ C CP + + E + CP+
Sbjct: 552 GRCYLNTVNGQC-ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQ 610
Query: 188 GPSKDN--GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLCRDIDECDM 244
G + N DINEC + G C C N Y C C PG D + C M
Sbjct: 611 GYKRLNLTHCQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISM 669
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG 286
Q G C + G TC P R ++ C + + G
Sbjct: 670 LQ-----GLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWG 706
Score = 46.8 bits (106), Expect = 2e-04
Identities = 21/37 (56%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
C D DEC A C G CVNT+GS+ C C P LTLD
Sbjct: 1526 CEDHDECQDLA--CENGECVNTEGSFHCFCSPPLTLD 1560
Score = 46.4 bits (105), Expect = 2e-04
Identities = 20/39 (51%), Positives = 23/39 (58%), Gaps = 3/39 (7%)
Query: 197 DINECTAVPGA---CPHGSCENLEPGYRCICDPGYHPDA 232
D+NEC + G C HG CEN E YRC C PGY +A
Sbjct: 1774 DVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEA 1812
Score = 45.6 bits (103), Expect = 4e-04
Identities = 26/53 (49%), Positives = 33/53 (62%), Gaps = 6/53 (11%)
Query: 399 KGFAKLDGA--TCRDVDECA-LS--AELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+GF +LD A C DV+EC L+ A LC G C NT+GSYRC C PG ++
Sbjct: 1761 EGF-QLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEA 1812
Score = 41.5 bits (93), Expect = 0.006
Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 13/98 (13%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA--PTAAGYCADVDECAADSMCKGGR 93
C+D++EC +C+ C NT GSY C C PG P+ + +D A SM + G
Sbjct: 620 CQDINECL-TLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD----KAISMLQ-GL 673
Query: 94 CVNSEGSFQCVCEAGYRPTATRGACVDV-----DECEE 126
C S G C R T C V ECE+
Sbjct: 674 CYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEK 711
Score = 41.5 bits (93), Expect = 0.006
Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 23/106 (21%)
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYER 299
+EC + C G+C +TC C EG + + C D++EC+
Sbjct: 1735 EECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECD-------------- 1779
Query: 300 GDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
D+ A C +G C NT G + C C GYV +A C
Sbjct: 1780 -DLNGP-------AVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 35.5 bits (78), Expect = 0.39
Identities = 10/22 (45%), Positives = 15/22 (68%)
Query: 6 MCTNGICKNIDGGFECICKPGY 27
+C +G C+N +G + C C PGY
Sbjct: 1787 LCVHGYCENTEGSYRCHCSPGY 1808
>BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming growth
factor beta binding protein 2 protein.
Length = 1821
Score = 273 bits (669), Expect = 1e-72
Identities = 164/466 (35%), Positives = 220/466 (47%), Gaps = 52/466 (11%)
Query: 10 GICKNIDGGFECICKPGYESGSEGAL--CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEP 67
G C N G + C C PGY + GA C+D++EC + P VC G+C NT GSY C C+
Sbjct: 900 GRCINRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQ 958
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCV-CEAGYRPTATRGACVDVDECEE 126
G+ G+C D++EC C GRCVNS GS+ C+ CE GYR G+CVDV+EC
Sbjct: 959 GYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLT 1016
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQA--CPAQGSELYAV 183
VC +G+C N GSFRC C G+ +++D + C + + SC C
Sbjct: 1017 PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACS 1076
Query: 184 LCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRC-ICDPGYHPDADG-LCRD 238
C G + G D++EC A PG CP G C N + C CD GY P G C D
Sbjct: 1077 ACENGYWVNEDGTACEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCED 1135
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE-THYIESDY 297
+DEC+ QS C GG+C+NT GS+ C+CP+G + +C D++EC GE + E
Sbjct: 1136 VDECEDPQSSCLGGECKNTVGSYQCLCPQGFQ-LANGTVCEDVNECMGEEHCAPHGECLN 1194
Query: 298 ERGDI----PPTFPTR---------TELAS--PCDNGRCINTHGGFECECELGYVLDATA 342
G P F + E A+ PC G C+NT G F C CE G+ +
Sbjct: 1195 SHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPES 1254
Query: 343 QRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA 402
C+D +D +CE + +C S G GF
Sbjct: 1255 GECVD----------ID-ECEDYGDPVCGTWKCENSPG---------SYRCVLGCQPGFH 1294
Query: 403 KLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
C D+DECA + G C NTDGS+RC C G + +G
Sbjct: 1295 MAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSG 1340
Score = 231 bits (565), Expect = 4e-60
Identities = 149/474 (31%), Positives = 208/474 (43%), Gaps = 60/474 (12%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCL 64
+C G C N+ G+ C+C PGY+ A C D +EC +P C+ +GRC N GSY+C
Sbjct: 855 VCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CKGKGRCINRVGSYSCF 912
Query: 65 CEPGFAPTAAG---YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG+ +G C D++EC +C GG+C N+EGS+ C C+ GY +G C D+
Sbjct: 913 CYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGY-IMVRKGHCQDI 971
Query: 122 DECEEQRVCRNGRCHNTPGSFRC-ECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
+EC C +GRC N+PGS+ C C G+ + + L GV
Sbjct: 972 NECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGS 1031
Query: 181 YAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYRC-ICDPGYHPDADG-L 235
+ C +G S + G D++EC A +CP G C N E + C C+ GY + DG
Sbjct: 1032 FRCSCEQGYEVTSDEKGCQDVDEC-ASRASCPTGLCLNTEGSFACSACENGYWVNEDGTA 1090
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCV-CPEGTRHEPELQLCRDIDECEGETETHYIE 294
C D+DEC C G C NTAGSF+C C G R P C D+DECE + ++ +
Sbjct: 1091 CEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECE-DPQSSCLG 1148
Query: 295 SDYER--GDIPPTFPTRTELA--SPCD-------------NGRCINTHGGFECECELGYV 337
+ + G P +LA + C+ +G C+N+HG F C C G+V
Sbjct: 1149 GECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFV 1208
Query: 338 LDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
C D + V G C C C G
Sbjct: 1209 SAEGGTSCQDVDECATTDPCVGGHCVNTEGSF----NCLCETGFQ--------------- 1249
Query: 398 XKGFAKLDGATCRDVDECA-LSAELCAGGTCVNTDGSYRC--DCPPGLTLDSTG 448
+ C D+DEC +C C N+ GSYRC C PG + G
Sbjct: 1250 ----PSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG 1299
Score = 225 bits (549), Expect = 3e-58
Identities = 148/451 (32%), Positives = 207/451 (45%), Gaps = 25/451 (5%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C+ G C N +G + C C GY +G C+D++ECR +P C GRC N+ GSYTCL
Sbjct: 938 GVCSGGQCTNTEGSYHCECDQGYIMVRKGH-CQDINECR-HPGTCPDGRCVNSPGSYTCL 995
Query: 65 -CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
CE G+ + G C DV+EC +C G+C N EGSF+C CE GY T+ C DVDE
Sbjct: 996 ACEEGYRGQS-GSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDE 1054
Query: 124 CEEQRVCRNGRCHNTPGSFRCE-CLPGFTLSNDGRTCLGL-KLGWGVSCQA--CPAQGSE 179
C + C G C NT GSF C C G+ ++ DG C L + + C + C
Sbjct: 1055 CASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGS 1114
Query: 180 LYAVLCPEG--PSK-DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
C G PS + D++EC +C G C+N Y+C+C G+ +C
Sbjct: 1115 FSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVC 1174
Query: 237 RDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIES 295
D++EC M + +CA G+C N+ GSF C+C G C+D+DEC
Sbjct: 1175 EDVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHC 1233
Query: 296 DYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGS--C 353
G T + SP ++G C++ ECE + G + T +C +N GS C
Sbjct: 1234 VNTEGSFNCLCETGFQ-PSP-ESGECVDID---ECE-DYGDPVCGT-WKC-ENSPGSYRC 1285
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGL-AWGSXXXXXXXXXXXXXKGF-AKLDGATCRD 411
G A + + EC + G +GF G C D
Sbjct: 1286 VLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVD 1345
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPGL 442
V+EC L +C C N +GS+ C C L
Sbjct: 1346 VNECELMLAVCGAALCENVEGSFLCLCASDL 1376
Score = 225 bits (549), Expect = 3e-58
Identities = 154/469 (32%), Positives = 205/469 (43%), Gaps = 35/469 (7%)
Query: 7 CTNGICKNIDGGFEC-ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL- 64
C G+C N +G F C C+ GY +G C D+DEC P VC G C NTAGS++C
Sbjct: 1061 CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTNTAGSFSCKD 1119
Query: 65 CEPGFAPTAAG-YCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+ G+ P+ G C DVDEC S C GG C N+ GS+QC+C G++ A C DV+
Sbjct: 1120 CDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQ-LANGTVCEDVN 1178
Query: 123 ECEEQRVCR-NGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSE- 179
EC + C +G C N+ GSF C C PGF + G +C + + C +E
Sbjct: 1179 ECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEG 1238
Query: 180 LYAVLCPEG--PSKDNGGA-DINECTAVPG-ACPHGSCENLEPGYRCI--CDPGYHPDAD 233
+ LC G PS ++G DI+EC C CEN YRC+ C PG+H +
Sbjct: 1239 SFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPN 1298
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G C DIDEC + G C NT GSF C+C +G P C D++ECE
Sbjct: 1299 GDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGA 1358
Query: 294 E-SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGS 352
+ G + E G C G + E A A +D G
Sbjct: 1359 ALCENVEGSFLCLCASDLE-EYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQ 1417
Query: 353 CWRRVVDGQCEAAAPELLLRQECCCSVGLAWG-------SXXXXXXXXXXXXXKGFAKLD 405
C + + ECCC+ G +WG S KG+ ++
Sbjct: 1418 KGH----APCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVE 1473
Query: 406 GATC------RDVDECALSAE-LCAGGTCVNTDGSYRCDCPPGLTLDST 447
GA D DEC + LC G C+NT Y C C PG D++
Sbjct: 1474 GAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDAS 1522
Score = 207 bits (505), Expect = 7e-53
Identities = 149/427 (34%), Positives = 189/427 (44%), Gaps = 71/427 (16%)
Query: 39 VDECRDNP-RVCRRGRCRNTAGSYTCLCEPGFA--PTAAGYCADVDECAADSMCKG-GRC 94
+D C VC G C N Y C+C PG+ P+ A YC D +EC D CKG GRC
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQA-YCTDDNECLRDP-CKGKGRC 902
Query: 95 VNSEGSFQCVCEAGYRPTATRGA---CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT 151
+N GS+ C C GY AT GA C D++ECE+ VC G+C NT GS+ CEC G+
Sbjct: 903 INRVGSYSCFCYPGYT-LATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYI 961
Query: 152 LSNDGRTCLGL-KLGWGVSCQ--ACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGA 207
+ G C + + +C C + C EG +G D+NEC PG
Sbjct: 962 MVRKGH-CQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLT-PGV 1019
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTC-VC 265
C HG C NLE +RC C+ GY +D C+D+DEC S C G C NT GSF C C
Sbjct: 1020 CAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRAS-CPTGLCLNTEGSFACSAC 1078
Query: 266 PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTH 325
G + C D+DEC FP C +G C NT
Sbjct: 1079 ENGYWVNEDGTACEDLDEC--------------------AFP------GVCPSGVCTNTA 1112
Query: 326 GGFEC-ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG 384
G F C +C+ GY C D VD +CE L EC +VG
Sbjct: 1113 GSFSCKDCDGGYRPSPLGDSCED----------VD-ECEDPQSSCL-GGECKNTVG---- 1156
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLT 443
+GF +G C DV+EC + E CA G C+N+ GS+ C C PG
Sbjct: 1157 -------SYQCLCPQGFQLANGTVCEDVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFV 1208
Query: 444 LDSTGTA 450
GT+
Sbjct: 1209 SAEGGTS 1215
Score = 204 bits (497), Expect = 7e-52
Identities = 131/388 (33%), Positives = 181/388 (46%), Gaps = 50/388 (12%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G CKN G ++C+C G++ + G +C DV+EC G C N+ GS+ CLC
Sbjct: 1146 CLGGECKNTVGSYQCLCPQGFQLAN-GTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCA 1204
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
PGF G C DVDECA C GG CVN+EGSF C+CE G++P+ G CVD+DECE
Sbjct: 1205 PGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECE 1264
Query: 126 E--QRVCRNGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGVSCQA---CP-AQ 176
+ VC +C N+PGS+RC C PGF ++ +G C+ + + C + C
Sbjct: 1265 DYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTD 1323
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCIC--DPGYHPD 231
GS + LC +G G D+NEC + C CEN+E + C+C D +
Sbjct: 1324 GS--FRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDA 1381
Query: 232 ADGLCR-------DIDECDM--H-----QSYCAGGQ-----CRNTAGSFT----CVCPEG 268
+G CR + E H + C GQ C + G T C C +G
Sbjct: 1382 QEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQG 1441
Query: 269 TRHEPELQLCRDIDECEGE----TETHYI--ESDYERGDIPPTFPTRTELASP--CDNGR 320
LC D E + YI E + G T + P C NGR
Sbjct: 1442 ASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGR 1501
Query: 321 CINTHGGFECECELGYVLDATAQRCLDN 348
C+NT G+ C C G+ DA+ ++C D+
Sbjct: 1502 CLNTVPGYVCLCNPGFHYDASHKKCEDH 1529
Score = 186 bits (452), Expect = 2e-46
Identities = 127/417 (30%), Positives = 178/417 (42%), Gaps = 67/417 (16%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCL- 64
C G C N +G F C+C+ G++ E C D+DEC D VC +C N+ GSY C+
Sbjct: 1228 CVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVL 1287
Query: 65 -CEPGFAPTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+PGF G C D+DECA D+MC G C N++GSF+C+C+ G+ + + CVDV+
Sbjct: 1288 GCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVN 1347
Query: 123 ECEEQ-RVCRNGRCHNTPGSFRCECLPGFTL--SNDG----RTCLGLKLGWGVSCQACPA 175
ECE VC C N GSF C C + +G R G + + PA
Sbjct: 1348 ECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPA 1407
Query: 176 QGS-ELYAVLCPEGPSKDNGGADIN--ECTAVPGACPHGSCE------NLEPGYRCICDP 226
+ Y+ P G + EC GA +C+ + E C
Sbjct: 1408 PTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGK 1467
Query: 227 GYHPDADG------LCRDIDECDMH-QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR 279
GY P + D DEC + C G+C NT + C+C G ++ + C
Sbjct: 1468 GYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCE 1527
Query: 280 DIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLD 339
D DEC+ +LA C+NG C+NT G F C C LD
Sbjct: 1528 DHDECQ-------------------------DLA--CENGECVNTEGSFHCFCSPPLTLD 1560
Query: 340 ATAQRCLDNRRGS------------CWRRVVDGQC-EAAAPELLLRQECCCSVGLAW 383
+ QRC+++ + CW++V + C E ECCC G AW
Sbjct: 1561 LSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAW 1617
Score = 175 bits (427), Expect = 2e-43
Identities = 131/409 (32%), Positives = 170/409 (41%), Gaps = 53/409 (12%)
Query: 80 VDECAADS--MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN 137
+D CAA + +C G CVN ++CVC GY+ ++ C D +EC GRC N
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 904
Query: 138 TPGSFRCECLPGFTLSNDGRT--CLGL----KLGWGVSCQACPAQGSELYAVLCPEGPSK 191
GS+ C C PG+TL+ G T C + + G Q +GS Y C +G
Sbjct: 905 RVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGS--YHCECDQGYIM 962
Query: 192 DNGG--ADINECTAVPGACPHGSCENLEPGYRCI-CDPGYHPDADGLCRDIDECDMHQSY 248
G DINEC PG CP G C N Y C+ C+ GY + G C D++EC +
Sbjct: 963 VRKGHCQDINECRH-PGTCPDGRCVNSPGSYTCLACEEGYRGQS-GSCVDVNEC-LTPGV 1019
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC--------------EGETETHYIE 294
CA G+C N GSF C C +G + + C+D+DEC EG E
Sbjct: 1020 CAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACE 1079
Query: 295 SDYERGDIPPTFPTRTELASP--CDNGRCINTHGGFEC-ECELGYVLDATAQRCLDNRR- 350
+ Y + E A P C +G C NT G F C +C+ GY C D
Sbjct: 1080 NGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDEC 1139
Query: 351 ---------GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSX--------XXXXXXX 393
G C V QC L C V G
Sbjct: 1140 EDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSF 1199
Query: 394 XXXXXKGFAKLDGAT-CRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF +G T C+DVDECA + + C GG CVNT+GS+ C C G
Sbjct: 1200 FCLCAPGFVSAEGGTSCQDVDECA-TTDPCVGGHCVNTEGSFNCLCETG 1247
Score = 158 bits (383), Expect = 4e-38
Identities = 100/319 (31%), Positives = 140/319 (43%), Gaps = 32/319 (10%)
Query: 6 MCTNGICKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
+C C+N G + C+ C+PG+ G C D+DEC ++ G C NT GS+ C
Sbjct: 1270 VCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDECANDTMCGSHGFCDNTDGSFRC 1328
Query: 64 LCEPGFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVC----------EAGYRP 111
LC+ GF + +G+ C DV+EC ++C C N EGSF C+C E RP
Sbjct: 1329 LCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRP 1388
Query: 112 TATRGACV-DVDECEEQRVCRNGRCHN-TPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS 169
G + + + C++ G C + G + C WG +
Sbjct: 1389 RGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRN-TTQAECCCTQGASWGDA 1447
Query: 170 CQACPAQGSELYAVLCPEGPSK-DNGGA---------DINECTAV-PGACPHGSCENLEP 218
C CP++ S ++ +CP G GA D +EC PG CP+G C N P
Sbjct: 1448 CDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVP 1507
Query: 219 GYRCICDPGYHPDAD-GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL 277
GY C+C+PG+H DA C D DEC C G+C NT GSF C C + Q
Sbjct: 1508 GYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLTLDLSQQR 1565
Query: 278 CRDIDECEGETETHYIESD 296
C + + H I D
Sbjct: 1566 CMNSTSSTEDLPDHDIHMD 1584
Score = 88.6 bits (210), Expect = 4e-17
Identities = 134/500 (26%), Positives = 184/500 (36%), Gaps = 93/500 (18%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C + C N G + C C+PG + C D +G C + G TC
Sbjct: 630 GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC-----VSDKAISMLQGLCYRSLGPGTCT 684
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPT-ATRGACVDVDE 123
T C A S C+ +E +F+ +C AG+ T A+ + + +
Sbjct: 685 LPLAQRITKQICCCSRVGKAWGSECEKCPLPGTE-AFREICPAGHGYTYASSDIRLSMRK 743
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-----SCQACPAQGS 178
EE+ + R R G LPG R L G QA S
Sbjct: 744 AEEEELARPPR---EQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTS 800
Query: 179 ELYAVLCPEG-----PSKDNGGADINE-----------CTAVPG--ACPHGSCENLEPG- 219
+A G P + G A+I E + PG C G+ PG
Sbjct: 801 VTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGT 860
Query: 220 -------YRCICDPGY--HPDADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEG- 268
YRC+C PGY HP + C D +EC + C G G+C N GS++C C G
Sbjct: 861 CVNLPDGYRCVCSPGYQLHP-SQAYCTDDNEC--LRDPCKGKGRCINRVGSYSCFCYPGY 917
Query: 269 -TRHEPELQLCRDIDECE-------GE---TETHYIESDYERGDI---PPTFPTRTELAS 314
Q C+DI+ECE G+ TE Y + ++G I E
Sbjct: 918 TLATSGATQECQDINECEQPGVCSGGQCTNTEGSY-HCECDQGYIMVRKGHCQDINECRH 976
Query: 315 P--CDNGRCINTHGGFEC-ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLL 371
P C +GRC+N+ G + C CE GY + C+D G+C
Sbjct: 977 PGTCPDGRCVNSPGSYTCLACEEGY--RGQSGSCVDVNECLTPGVCAHGKCTNLEGSF-- 1032
Query: 372 RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTD 431
C C G S D C+DVDECA A C G C+NT+
Sbjct: 1033 --RCSCEQGYEVTS-------------------DEKGCQDVDECASRAS-CPTGLCLNTE 1070
Query: 432 GSYRCD-CPPGLTLDSTGTA 450
GS+ C C G ++ GTA
Sbjct: 1071 GSFACSACENGYWVNEDGTA 1090
Score = 77.8 bits (183), Expect = 7e-14
Identities = 88/356 (24%), Positives = 126/356 (35%), Gaps = 48/356 (13%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C NG C N G+ C+C PG+ + C D DEC+D C G C NT GS+ C
Sbjct: 1495 GLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQD--LACENGECVNTEGSFHCF 1552
Query: 65 CE-PGFAPTAAGYCADVD---ECAADSMCKGGRCVNSEGSFQCVCEA-GYRPTATRGACV 119
C P + C + E D C + C G+R T T C
Sbjct: 1553 CSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQ 1612
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D + +Q C C + + + + + G+ P
Sbjct: 1613 DGEAWSQQ--C--ALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYG----PGPDDL 1664
Query: 180 LYAVLCPEGPSKDN--GGADINECTAVPGACPHGSCEN--LE-PGYRCICDPGY---HPD 231
Y++ P+G N G D A P H + LE P P Y HP+
Sbjct: 1665 HYSIYGPDGAPFYNYLGPEDTVPDPAFPNTAGHSADRTPILESPLQPSELQPHYVASHPE 1724
Query: 232 ADGLCRDI--DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE 289
+ +EC + C G+C +TC C EG + + C D++EC+
Sbjct: 1725 PPAGFEGLQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECD---- 1779
Query: 290 THYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
D+ A C +G C NT G + C C GYV +A C
Sbjct: 1780 -----------DLNGP-------AVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 75.8 bits (178), Expect = 3e-13
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 4/134 (2%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ +C D++EC +CK CVN+ GS+ C C G +R CV
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS---- 663
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
++ G C+ + G C ++ C + WG C+ CP G+E + +
Sbjct: 664 DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREI 723
Query: 185 CPEGPSKDNGGADI 198
CP G +DI
Sbjct: 724 CPAGHGYTYASSDI 737
Score = 70.5 bits (165), Expect = 1e-11
Identities = 38/105 (36%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG----------SXXXXXXXXXXXXXKG 400
G C+ V+GQC EL +++CC SVG WG +G
Sbjct: 552 GRCYLNTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQG 611
Query: 401 FAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
+ +L+ C+D++EC L+ LC CVNT GSY C C PGL LD
Sbjct: 612 YKRLNLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLD 655
Score = 60.1 bits (139), Expect = 2e-08
Identities = 78/320 (24%), Positives = 108/320 (33%), Gaps = 40/320 (12%)
Query: 38 DVDECRD-NPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVN 96
D DEC P +C GRC NT Y CLC PGF Y A +C C+ C N
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFH-----YDASHKKCEDHDECQDLACEN 1539
Query: 97 SEGSFQCV-CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSND 155
E CV E + + +D+ + RC N+ S E LP + D
Sbjct: 1540 GE----CVNTEGSFHCFCSPPLTLDLSQ---------QRCMNSTSS--TEDLPDHDIHMD 1584
Query: 156 -------GRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGAC 208
C G + C Q E ++ C P + + C
Sbjct: 1585 ICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSE-VYAQLCNVARIEA 1643
Query: 209 PHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
+ + PGY Y P D L I D Y G +T P
Sbjct: 1644 EREAGVHFRPGYE------YGPGPDDLHYSIYGPDGAPFYNYLGP-EDTVPD--PAFPNT 1694
Query: 269 TRHEPELQLCRDIDECEGETETHYIESDYER-GDIPPTFPTRTELASPCDNGRCINTHGG 327
H + + E + HY+ S E + + C+NGRC+ G
Sbjct: 1695 AGHSADRTPILESPLQPSELQPHYVASHPEPPAGFEGLQAEECGILNGCENGRCVRVREG 1754
Query: 328 FECECELGYVLDATAQRCLD 347
+ C+C G+ LDA C+D
Sbjct: 1755 YTCDCFEGFQLDAAHMACVD 1774
Score = 51.6 bits (118), Expect = 6e-06
Identities = 45/162 (27%), Positives = 63/162 (38%), Gaps = 15/162 (9%)
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQACPAQGS----ELYAVLCPE 187
GRC+ + +C P L+ C + WGV+ C CP + + E + CP+
Sbjct: 552 GRCYLNTVNGQC-ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQ 610
Query: 188 GPSKDN--GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLCRDIDECDM 244
G + N DINEC + G C C N Y C C PG D + C M
Sbjct: 611 GYKRLNLTHCQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISM 669
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG 286
Q G C + G TC P R ++ C + + G
Sbjct: 670 LQ-----GLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWG 706
Score = 46.8 bits (106), Expect = 2e-04
Identities = 21/37 (56%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
C D DEC A C G CVNT+GS+ C C P LTLD
Sbjct: 1526 CEDHDECQDLA--CENGECVNTEGSFHCFCSPPLTLD 1560
Score = 45.6 bits (103), Expect = 4e-04
Identities = 26/53 (49%), Positives = 33/53 (62%), Gaps = 6/53 (11%)
Query: 399 KGFAKLDGA--TCRDVDECA-LS--AELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+GF +LD A C DV+EC L+ A LC G C NT+GSYRC C PG ++
Sbjct: 1761 EGF-QLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEA 1812
Score = 41.5 bits (93), Expect = 0.006
Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 13/98 (13%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA--PTAAGYCADVDECAADSMCKGGR 93
C+D++EC +C+ C NT GSY C C PG P+ + +D A SM + G
Sbjct: 620 CQDINECL-TLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD----KAISMLQ-GL 673
Query: 94 CVNSEGSFQCVCEAGYRPTATRGACVDV-----DECEE 126
C S G C R T C V ECE+
Sbjct: 674 CYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEK 711
>AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming growth
factor beta binding protein 2 variant protein.
Length = 1700
Score = 273 bits (669), Expect = 1e-72
Identities = 164/466 (35%), Positives = 220/466 (47%), Gaps = 52/466 (11%)
Query: 10 GICKNIDGGFECICKPGYESGSEGAL--CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEP 67
G C N G + C C PGY + GA C+D++EC + P VC G+C NT GSY C C+
Sbjct: 779 GRCINRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQ 837
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCV-CEAGYRPTATRGACVDVDECEE 126
G+ G+C D++EC C GRCVNS GS+ C+ CE GYR G+CVDV+EC
Sbjct: 838 GYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLT 895
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQA--CPAQGSELYAV 183
VC +G+C N GSFRC C G+ +++D + C + + SC C
Sbjct: 896 PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACS 955
Query: 184 LCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRC-ICDPGYHPDADG-LCRD 238
C G + G D++EC A PG CP G C N + C CD GY P G C D
Sbjct: 956 ACENGYWVNEDGTACEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCED 1014
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE-THYIESDY 297
+DEC+ QS C GG+C+NT GS+ C+CP+G + +C D++EC GE + E
Sbjct: 1015 VDECEDPQSSCLGGECKNTVGSYQCLCPQGFQ-LANGTVCEDVNECMGEEHCAPHGECLN 1073
Query: 298 ERGDI----PPTFPTR---------TELAS--PCDNGRCINTHGGFECECELGYVLDATA 342
G P F + E A+ PC G C+NT G F C CE G+ +
Sbjct: 1074 SHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPES 1133
Query: 343 QRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA 402
C+D +D +CE + +C S G GF
Sbjct: 1134 GECVD----------ID-ECEDYGDPVCGTWKCENSPG---------SYRCVLGCQPGFH 1173
Query: 403 KLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
C D+DECA + G C NTDGS+RC C G + +G
Sbjct: 1174 MAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSG 1219
Score = 231 bits (565), Expect = 4e-60
Identities = 149/474 (31%), Positives = 208/474 (43%), Gaps = 60/474 (12%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCL 64
+C G C N+ G+ C+C PGY+ A C D +EC +P C+ +GRC N GSY+C
Sbjct: 734 VCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CKGKGRCINRVGSYSCF 791
Query: 65 CEPGFAPTAAG---YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG+ +G C D++EC +C GG+C N+EGS+ C C+ GY +G C D+
Sbjct: 792 CYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGY-IMVRKGHCQDI 850
Query: 122 DECEEQRVCRNGRCHNTPGSFRC-ECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
+EC C +GRC N+PGS+ C C G+ + + L GV
Sbjct: 851 NECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGS 910
Query: 181 YAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYRC-ICDPGYHPDADG-L 235
+ C +G S + G D++EC A +CP G C N E + C C+ GY + DG
Sbjct: 911 FRCSCEQGYEVTSDEKGCQDVDEC-ASRASCPTGLCLNTEGSFACSACENGYWVNEDGTA 969
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCV-CPEGTRHEPELQLCRDIDECEGETETHYIE 294
C D+DEC C G C NTAGSF+C C G R P C D+DECE + ++ +
Sbjct: 970 CEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECE-DPQSSCLG 1027
Query: 295 SDYER--GDIPPTFPTRTELA--SPCD-------------NGRCINTHGGFECECELGYV 337
+ + G P +LA + C+ +G C+N+HG F C C G+V
Sbjct: 1028 GECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFV 1087
Query: 338 LDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
C D + V G C C C G
Sbjct: 1088 SAEGGTSCQDVDECATTDPCVGGHCVNTEGSF----NCLCETGFQ--------------- 1128
Query: 398 XKGFAKLDGATCRDVDECA-LSAELCAGGTCVNTDGSYRC--DCPPGLTLDSTG 448
+ C D+DEC +C C N+ GSYRC C PG + G
Sbjct: 1129 ----PSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG 1178
Score = 225 bits (549), Expect = 3e-58
Identities = 148/451 (32%), Positives = 207/451 (45%), Gaps = 25/451 (5%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C+ G C N +G + C C GY +G C+D++ECR +P C GRC N+ GSYTCL
Sbjct: 817 GVCSGGQCTNTEGSYHCECDQGYIMVRKGH-CQDINECR-HPGTCPDGRCVNSPGSYTCL 874
Query: 65 -CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
CE G+ + G C DV+EC +C G+C N EGSF+C CE GY T+ C DVDE
Sbjct: 875 ACEEGYRGQS-GSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDE 933
Query: 124 CEEQRVCRNGRCHNTPGSFRCE-CLPGFTLSNDGRTCLGL-KLGWGVSCQA--CPAQGSE 179
C + C G C NT GSF C C G+ ++ DG C L + + C + C
Sbjct: 934 CASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGS 993
Query: 180 LYAVLCPEG--PSK-DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
C G PS + D++EC +C G C+N Y+C+C G+ +C
Sbjct: 994 FSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVC 1053
Query: 237 RDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIES 295
D++EC M + +CA G+C N+ GSF C+C G C+D+DEC
Sbjct: 1054 EDVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHC 1112
Query: 296 DYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGS--C 353
G T + SP ++G C++ ECE + G + T +C +N GS C
Sbjct: 1113 VNTEGSFNCLCETGFQ-PSP-ESGECVDID---ECE-DYGDPVCGT-WKC-ENSPGSYRC 1164
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGL-AWGSXXXXXXXXXXXXXKGF-AKLDGATCRD 411
G A + + EC + G +GF G C D
Sbjct: 1165 VLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVD 1224
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPGL 442
V+EC L +C C N +GS+ C C L
Sbjct: 1225 VNECELMLAVCGAALCENVEGSFLCLCASDL 1255
Score = 225 bits (549), Expect = 3e-58
Identities = 154/469 (32%), Positives = 205/469 (43%), Gaps = 35/469 (7%)
Query: 7 CTNGICKNIDGGFEC-ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL- 64
C G+C N +G F C C+ GY +G C D+DEC P VC G C NTAGS++C
Sbjct: 940 CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTNTAGSFSCKD 998
Query: 65 CEPGFAPTAAG-YCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+ G+ P+ G C DVDEC S C GG C N+ GS+QC+C G++ A C DV+
Sbjct: 999 CDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQ-LANGTVCEDVN 1057
Query: 123 ECEEQRVCR-NGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSE- 179
EC + C +G C N+ GSF C C PGF + G +C + + C +E
Sbjct: 1058 ECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEG 1117
Query: 180 LYAVLCPEG--PSKDNGGA-DINECTAVPG-ACPHGSCENLEPGYRCI--CDPGYHPDAD 233
+ LC G PS ++G DI+EC C CEN YRC+ C PG+H +
Sbjct: 1118 SFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPN 1177
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G C DIDEC + G C NT GSF C+C +G P C D++ECE
Sbjct: 1178 GDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGA 1237
Query: 294 E-SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGS 352
+ G + E G C G + E A A +D G
Sbjct: 1238 ALCENVEGSFLCLCASDLE-EYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQ 1296
Query: 353 CWRRVVDGQCEAAAPELLLRQECCCSVGLAWG-------SXXXXXXXXXXXXXKGFAKLD 405
C + + ECCC+ G +WG S KG+ ++
Sbjct: 1297 KGH----APCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVE 1352
Query: 406 GATC------RDVDECALSAE-LCAGGTCVNTDGSYRCDCPPGLTLDST 447
GA D DEC + LC G C+NT Y C C PG D++
Sbjct: 1353 GAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDAS 1401
Score = 207 bits (505), Expect = 7e-53
Identities = 149/427 (34%), Positives = 189/427 (44%), Gaps = 71/427 (16%)
Query: 39 VDECRDNP-RVCRRGRCRNTAGSYTCLCEPGFA--PTAAGYCADVDECAADSMCKG-GRC 94
+D C VC G C N Y C+C PG+ P+ A YC D +EC D CKG GRC
Sbjct: 724 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQA-YCTDDNECLRDP-CKGKGRC 781
Query: 95 VNSEGSFQCVCEAGYRPTATRGA---CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT 151
+N GS+ C C GY AT GA C D++ECE+ VC G+C NT GS+ CEC G+
Sbjct: 782 INRVGSYSCFCYPGYT-LATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYI 840
Query: 152 LSNDGRTCLGL-KLGWGVSCQ--ACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGA 207
+ G C + + +C C + C EG +G D+NEC PG
Sbjct: 841 MVRKGH-CQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLT-PGV 898
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTC-VC 265
C HG C NLE +RC C+ GY +D C+D+DEC S C G C NT GSF C C
Sbjct: 899 CAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRAS-CPTGLCLNTEGSFACSAC 957
Query: 266 PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTH 325
G + C D+DEC FP C +G C NT
Sbjct: 958 ENGYWVNEDGTACEDLDEC--------------------AFP------GVCPSGVCTNTA 991
Query: 326 GGFEC-ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG 384
G F C +C+ GY C D VD +CE L EC +VG
Sbjct: 992 GSFSCKDCDGGYRPSPLGDSCED----------VD-ECEDPQSSCL-GGECKNTVG---- 1035
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLT 443
+GF +G C DV+EC + E CA G C+N+ GS+ C C PG
Sbjct: 1036 -------SYQCLCPQGFQLANGTVCEDVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFV 1087
Query: 444 LDSTGTA 450
GT+
Sbjct: 1088 SAEGGTS 1094
Score = 204 bits (497), Expect = 7e-52
Identities = 131/388 (33%), Positives = 181/388 (46%), Gaps = 50/388 (12%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G CKN G ++C+C G++ + G +C DV+EC G C N+ GS+ CLC
Sbjct: 1025 CLGGECKNTVGSYQCLCPQGFQLAN-GTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCA 1083
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
PGF G C DVDECA C GG CVN+EGSF C+CE G++P+ G CVD+DECE
Sbjct: 1084 PGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECE 1143
Query: 126 E--QRVCRNGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGVSCQA---CP-AQ 176
+ VC +C N+PGS+RC C PGF ++ +G C+ + + C + C
Sbjct: 1144 DYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTD 1202
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCIC--DPGYHPD 231
GS + LC +G G D+NEC + C CEN+E + C+C D +
Sbjct: 1203 GS--FRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDA 1260
Query: 232 ADGLCR-------DIDECDM--H-----QSYCAGGQ-----CRNTAGSFT----CVCPEG 268
+G CR + E H + C GQ C + G T C C +G
Sbjct: 1261 QEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQG 1320
Query: 269 TRHEPELQLCRDIDECEGE----TETHYI--ESDYERGDIPPTFPTRTELASP--CDNGR 320
LC D E + YI E + G T + P C NGR
Sbjct: 1321 ASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGR 1380
Query: 321 CINTHGGFECECELGYVLDATAQRCLDN 348
C+NT G+ C C G+ DA+ ++C D+
Sbjct: 1381 CLNTVPGYVCLCNPGFHYDASHKKCEDH 1408
Score = 184 bits (448), Expect = 6e-46
Identities = 126/417 (30%), Positives = 177/417 (42%), Gaps = 67/417 (16%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCL- 64
C G C N +G F C+C+ G++ E C D+DEC D VC +C N+ GSY C+
Sbjct: 1107 CVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVL 1166
Query: 65 -CEPGFAPTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+PGF G C D+DECA D+MC G C N++GSF+C+C+ G+ + + CVDV+
Sbjct: 1167 GCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVN 1226
Query: 123 ECEEQ-RVCRNGRCHNTPGSFRCECLPGFTL--SNDG----RTCLGLKLGWGVSCQACPA 175
ECE VC C N GSF C C + +G R G + + PA
Sbjct: 1227 ECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPA 1286
Query: 176 QGS-ELYAVLCPEGPSKDNGGADIN--ECTAVPGACPHGSCE------NLEPGYRCICDP 226
+ Y+ P G + EC GA +C+ + E C
Sbjct: 1287 PTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGK 1346
Query: 227 GYHPDADG------LCRDIDECDMH-QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR 279
GY P + D DEC + C G+C NT + C+C G ++ + C
Sbjct: 1347 GYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCE 1406
Query: 280 DIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLD 339
D DEC+ +LA C+NG C+NT G F C C LD
Sbjct: 1407 DHDECQ-------------------------DLA--CENGECVNTEGSFHCFCSPPLTLD 1439
Query: 340 ATAQRCLDNRRGS------------CWRRVVDGQC-EAAAPELLLRQECCCSVGLAW 383
+ QRC+++ + CW++ + C E ECCC G AW
Sbjct: 1440 LSQQRCMNSTSSTEDLPDHDIHMDICWKKATNDVCSEPLRGHRTTYTECCCQDGEAW 1496
Score = 175 bits (427), Expect = 2e-43
Identities = 131/409 (32%), Positives = 170/409 (41%), Gaps = 53/409 (12%)
Query: 80 VDECAADS--MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN 137
+D CAA + +C G CVN ++CVC GY+ ++ C D +EC GRC N
Sbjct: 724 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 783
Query: 138 TPGSFRCECLPGFTLSNDGRT--CLGL----KLGWGVSCQACPAQGSELYAVLCPEGPSK 191
GS+ C C PG+TL+ G T C + + G Q +GS Y C +G
Sbjct: 784 RVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGS--YHCECDQGYIM 841
Query: 192 DNGG--ADINECTAVPGACPHGSCENLEPGYRCI-CDPGYHPDADGLCRDIDECDMHQSY 248
G DINEC PG CP G C N Y C+ C+ GY + G C D++EC +
Sbjct: 842 VRKGHCQDINECRH-PGTCPDGRCVNSPGSYTCLACEEGYRGQS-GSCVDVNEC-LTPGV 898
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC--------------EGETETHYIE 294
CA G+C N GSF C C +G + + C+D+DEC EG E
Sbjct: 899 CAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACE 958
Query: 295 SDYERGDIPPTFPTRTELASP--CDNGRCINTHGGFEC-ECELGYVLDATAQRCLDNRR- 350
+ Y + E A P C +G C NT G F C +C+ GY C D
Sbjct: 959 NGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDEC 1018
Query: 351 ---------GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSX--------XXXXXXX 393
G C V QC L C V G
Sbjct: 1019 EDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSF 1078
Query: 394 XXXXXKGFAKLDGAT-CRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF +G T C+DVDECA + + C GG CVNT+GS+ C C G
Sbjct: 1079 FCLCAPGFVSAEGGTSCQDVDECA-TTDPCVGGHCVNTEGSFNCLCETG 1126
Score = 158 bits (383), Expect = 4e-38
Identities = 100/319 (31%), Positives = 140/319 (43%), Gaps = 32/319 (10%)
Query: 6 MCTNGICKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
+C C+N G + C+ C+PG+ G C D+DEC ++ G C NT GS+ C
Sbjct: 1149 VCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDECANDTMCGSHGFCDNTDGSFRC 1207
Query: 64 LCEPGFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVC----------EAGYRP 111
LC+ GF + +G+ C DV+EC ++C C N EGSF C+C E RP
Sbjct: 1208 LCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRP 1267
Query: 112 TATRGACV-DVDECEEQRVCRNGRCHN-TPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS 169
G + + + C++ G C + G + C WG +
Sbjct: 1268 RGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRN-TTQAECCCTQGASWGDA 1326
Query: 170 CQACPAQGSELYAVLCPEGPSK-DNGGA---------DINECTAV-PGACPHGSCENLEP 218
C CP++ S ++ +CP G GA D +EC PG CP+G C N P
Sbjct: 1327 CDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVP 1386
Query: 219 GYRCICDPGYHPDAD-GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL 277
GY C+C+PG+H DA C D DEC C G+C NT GSF C C + Q
Sbjct: 1387 GYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLTLDLSQQR 1444
Query: 278 CRDIDECEGETETHYIESD 296
C + + H I D
Sbjct: 1445 CMNSTSSTEDLPDHDIHMD 1463
Score = 88.6 bits (210), Expect = 4e-17
Identities = 134/500 (26%), Positives = 184/500 (36%), Gaps = 93/500 (18%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C + C N G + C C+PG + C D +G C + G TC
Sbjct: 509 GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC-----VSDKAISMLQGLCYRSLGPGTCT 563
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPT-ATRGACVDVDE 123
T C A S C+ +E +F+ +C AG+ T A+ + + +
Sbjct: 564 LPLAQRITKQICCCSRVGKAWGSECEKCPLPGTE-AFREICPAGHGYTYASSDIRLSMRK 622
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-----SCQACPAQGS 178
EE+ + R R G LPG R L G QA S
Sbjct: 623 AEEEELARPPR---EQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTS 679
Query: 179 ELYAVLCPEG-----PSKDNGGADINE-----------CTAVPG--ACPHGSCENLEPG- 219
+A G P + G A+I E + PG C G+ PG
Sbjct: 680 VTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGT 739
Query: 220 -------YRCICDPGY--HPDADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEG- 268
YRC+C PGY HP + C D +EC + C G G+C N GS++C C G
Sbjct: 740 CVNLPDGYRCVCSPGYQLHP-SQAYCTDDNEC--LRDPCKGKGRCINRVGSYSCFCYPGY 796
Query: 269 -TRHEPELQLCRDIDECE-------GE---TETHYIESDYERGDI---PPTFPTRTELAS 314
Q C+DI+ECE G+ TE Y + ++G I E
Sbjct: 797 TLATSGATQECQDINECEQPGVCSGGQCTNTEGSY-HCECDQGYIMVRKGHCQDINECRH 855
Query: 315 P--CDNGRCINTHGGFEC-ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLL 371
P C +GRC+N+ G + C CE GY + C+D G+C
Sbjct: 856 PGTCPDGRCVNSPGSYTCLACEEGY--RGQSGSCVDVNECLTPGVCAHGKCTNLEGSF-- 911
Query: 372 RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTD 431
C C G S D C+DVDECA A C G C+NT+
Sbjct: 912 --RCSCEQGYEVTS-------------------DEKGCQDVDECASRAS-CPTGLCLNTE 949
Query: 432 GSYRCD-CPPGLTLDSTGTA 450
GS+ C C G ++ GTA
Sbjct: 950 GSFACSACENGYWVNEDGTA 969
Score = 78.2 bits (184), Expect = 6e-14
Identities = 87/356 (24%), Positives = 127/356 (35%), Gaps = 48/356 (13%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C NG C N G+ C+C PG+ + C D DEC+D C G C NT GS+ C
Sbjct: 1374 GLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQD--LACENGECVNTEGSFHCF 1431
Query: 65 CE-PGFAPTAAGYCADVDECAADSMCKGGRC-VNSEGSFQCVCEA---GYRPTATRGACV 119
C P + C + D + + + VC G+R T T C
Sbjct: 1432 CSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKATNDVCSEPLRGHRTTYTECCCQ 1491
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D + +Q C C + + + + + G+ P
Sbjct: 1492 DGEAWSQQ--C--ALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYG----PGPDDL 1543
Query: 180 LYAVLCPEGPSKDN--GGADINECTAVPGACPHGSCEN--LE-PGYRCICDPGY---HPD 231
Y++ P+G N G D A P H + LE P P Y HP+
Sbjct: 1544 HYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYVASHPE 1603
Query: 232 ADGLCRDI--DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE 289
+ +EC + C G+C +TC C EG + + C D++EC+
Sbjct: 1604 PPAGFEGLQAEECGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECD---- 1658
Query: 290 THYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
D+ A C +G C NT G + C C GYV +A C
Sbjct: 1659 -----------DLNGP-------AVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1696
Score = 75.8 bits (178), Expect = 3e-13
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 4/134 (2%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ +C D++EC +CK CVN+ GS+ C C G +R CV
Sbjct: 487 CPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS---- 542
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
++ G C+ + G C ++ C + WG C+ CP G+E + +
Sbjct: 543 DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREI 602
Query: 185 CPEGPSKDNGGADI 198
CP G +DI
Sbjct: 603 CPAGHGYTYASSDI 616
Score = 70.5 bits (165), Expect = 1e-11
Identities = 38/105 (36%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG----------SXXXXXXXXXXXXXKG 400
G C+ V+GQC EL +++CC SVG WG +G
Sbjct: 431 GRCYLNTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQG 490
Query: 401 FAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
+ +L+ C+D++EC L+ LC CVNT GSY C C PGL LD
Sbjct: 491 YKRLNLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLD 534
Score = 60.1 bits (139), Expect = 2e-08
Identities = 78/320 (24%), Positives = 108/320 (33%), Gaps = 40/320 (12%)
Query: 38 DVDECRD-NPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVN 96
D DEC P +C GRC NT Y CLC PGF Y A +C C+ C N
Sbjct: 1364 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFH-----YDASHKKCEDHDECQDLACEN 1418
Query: 97 SEGSFQCV-CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSND 155
E CV E + + +D+ + RC N+ S E LP + D
Sbjct: 1419 GE----CVNTEGSFHCFCSPPLTLDLSQ---------QRCMNSTSS--TEDLPDHDIHMD 1463
Query: 156 -------GRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGAC 208
C G + C Q E ++ C P + + C
Sbjct: 1464 ICWKKATNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSE-VYAQLCNVARIEA 1522
Query: 209 PHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
+ + PGY Y P D L I D Y G +T P
Sbjct: 1523 EREAGVHFRPGYE------YGPGPDDLHYSIYGPDGAPFYNYLGP-EDTVPE--PAFPNT 1573
Query: 269 TRHEPELQLCRDIDECEGETETHYIESDYER-GDIPPTFPTRTELASPCDNGRCINTHGG 327
H + + E + HY+ S E + + C+NGRC+ G
Sbjct: 1574 AGHSADRTPILESPLQPSELQPHYVASHPEPPAGFEGLQAEECGILNGCENGRCVRVREG 1633
Query: 328 FECECELGYVLDATAQRCLD 347
+ C+C G+ LDA C+D
Sbjct: 1634 YTCDCFEGFQLDAAHMACVD 1653
Score = 51.6 bits (118), Expect = 6e-06
Identities = 45/162 (27%), Positives = 63/162 (38%), Gaps = 15/162 (9%)
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQACPAQGS----ELYAVLCPE 187
GRC+ + +C P L+ C + WGV+ C CP + + E + CP+
Sbjct: 431 GRCYLNTVNGQC-ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQ 489
Query: 188 GPSKDN--GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLCRDIDECDM 244
G + N DINEC + G C C N Y C C PG D + C M
Sbjct: 490 GYKRLNLTHCQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISM 548
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG 286
Q G C + G TC P R ++ C + + G
Sbjct: 549 LQ-----GLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWG 585
Score = 46.8 bits (106), Expect = 2e-04
Identities = 21/37 (56%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
C D DEC A C G CVNT+GS+ C C P LTLD
Sbjct: 1405 CEDHDECQDLA--CENGECVNTEGSFHCFCSPPLTLD 1439
Score = 45.6 bits (103), Expect = 4e-04
Identities = 26/53 (49%), Positives = 33/53 (62%), Gaps = 6/53 (11%)
Query: 399 KGFAKLDGA--TCRDVDECA-LS--AELCAGGTCVNTDGSYRCDCPPGLTLDS 446
+GF +LD A C DV+EC L+ A LC G C NT+GSYRC C PG ++
Sbjct: 1640 EGF-QLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEA 1691
Score = 41.5 bits (93), Expect = 0.006
Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 13/98 (13%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA--PTAAGYCADVDECAADSMCKGGR 93
C+D++EC +C+ C NT GSY C C PG P+ + +D A SM + G
Sbjct: 499 CQDINECL-TLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD----KAISMLQ-GL 552
Query: 94 CVNSEGSFQCVCEAGYRPTATRGACVDV-----DECEE 126
C S G C R T C V ECE+
Sbjct: 553 CYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEK 590
>AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital
contractural arachnodactyly) variant protein.
Length = 1976
Score = 271 bits (665), Expect = 3e-72
Identities = 166/493 (33%), Positives = 226/493 (45%), Gaps = 55/493 (11%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
GMCT G C+N G F+C C G+ E C D+DECR +P +C G C NT GS+ C
Sbjct: 146 GMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECE 205
Query: 65 CEPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C G+ C D+DEC + +C+GG CVN+EGSFQC C G+ + +R CVD+
Sbjct: 206 CFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDI 265
Query: 122 DECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQ 176
+EC +CRNG+C N G+++C C PG+ + D + C + + G Q ++
Sbjct: 266 NECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSE 325
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
GS Y C EG + G ADI+EC P C G C N+ YRC+C G+ D
Sbjct: 326 GS--YECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMD 383
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C D++ECD++ + C G+C NT GSF C C G + C D+DEC E H
Sbjct: 384 MKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDEC--EIGAHN 441
Query: 293 IESDYERGDIPPTFPTRTELA-----------SPCDNG--------RCINTHGGFECECE 333
+ +IP +F C NG +C+NT G + C C
Sbjct: 442 CDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACS 501
Query: 334 LGYVLD----ATAQRCLDN----RRGSCWRRVVDGQCEAA---APELLLR-----QECCC 377
G+ D + C +N G C +CE P R EC
Sbjct: 502 EGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSF 561
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLD--GATCRDVDECALSAELCAGGTCVNTDGSYR 435
+G+ G+ +LD G C D+DECA C G CVNT G Y
Sbjct: 562 QNICVFGTCNNLPGMFHCICDDGY-ELDRTGGNCTDIDECADPIN-CVNGLCVNTPGRYE 619
Query: 436 CDCPPGLTLDSTG 448
C+CPP L+ TG
Sbjct: 620 CNCPPDFQLNPTG 632
Score = 249 bits (610), Expect = 1e-65
Identities = 149/450 (33%), Positives = 213/450 (47%), Gaps = 48/450 (10%)
Query: 19 FECICK--PGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT-AAG 75
F+ IC PG+ D+DEC++ P +C G C N GS+ C C GF+
Sbjct: 851 FKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLL 910
Query: 76 YCADVDECA-ADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRN 132
C D+DEC+ D++C + C+NS GS++C C AG++ + GACVD +EC E VC +
Sbjct: 911 VCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFK-LSPNGACVDRNECLEIPNVCSH 969
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE-LYAVLCPEG--P 189
G C + GS++C C GF S D C+ + C + + Y LC G
Sbjct: 970 GLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFEL 1029
Query: 190 SKDNGGADINECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQS 247
+ +N DI+EC++ G C +G C N ++C+C+ GY DG C D +EC
Sbjct: 1030 THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPG 1089
Query: 248 YCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFP 307
C+ G C+N GSF C+CP G +E + + C DI+EC+ +
Sbjct: 1090 SCSPGTCQNLEGSFRCICPPG--YEVKSENCIDINECDEDPNI----------------- 1130
Query: 308 TRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAP 367
C G C NT GGF+C C G+VL +RC D R+ C+ +G+C
Sbjct: 1131 --------CLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKA 1182
Query: 368 ELLLRQECCCS--VGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-------RDVDECALS 418
+ +CCCS G WG + T DV+EC S
Sbjct: 1183 FNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLES 1242
Query: 419 AELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+C+ G C+NTDGS+RC+CP G LD TG
Sbjct: 1243 PGICSNGQCINTDGSFRCECPMGYNLDYTG 1272
Score = 241 bits (591), Expect = 3e-63
Identities = 153/452 (33%), Positives = 210/452 (46%), Gaps = 41/452 (9%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC 63
G+C NG+C N G F C C G+ +C D+DEC + +C+R C N+ GSY C
Sbjct: 881 GICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRC 940
Query: 64 LCEPGFAPTAAGYCADVDEC-AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C GF + G C D +EC ++C G CV+ +GS+QC+C G++ + + C+DVD
Sbjct: 941 ECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVD 1000
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG---SE 179
EC E+ C NG C NT GS+ C C PGF L+++ CL + Q C G +E
Sbjct: 1001 EC-ERHPCGNGTCKNTVGSYNCLCYPGFELTHN-NDCLDIDECSSFFGQVC-RNGRCFNE 1057
Query: 180 L--YAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
+ + LC EG G D NEC A+PG+C G+C+NLE +RCIC PGY ++
Sbjct: 1058 IGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN 1117
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
C DI+ECD + C G C NT G F C+CP G + C D T +
Sbjct: 1118 -CIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD-------TRQSFCF 1169
Query: 295 SDYERG--DIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYVLDATAQRCLDNRRG 351
+++E G +P F T A C C G G+ CEL D A + L
Sbjct: 1170 TNFENGKCSVPKAF--NTTKAKCC----CSKMPGEGWGDPCELCPKDDEVAFQDLCPYGH 1223
Query: 352 SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD--GATC 409
+ D + + EC S G+ LD G C
Sbjct: 1224 GTVPSLHDTREDV--------NECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRC 1275
Query: 410 RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
D DEC++ C GTC N GS+ C+C G
Sbjct: 1276 VDTDECSI-GNPCGNGTCTNVIGSFECNCNEG 1306
Score = 239 bits (584), Expect = 2e-62
Identities = 161/465 (34%), Positives = 212/465 (45%), Gaps = 56/465 (12%)
Query: 2 TNG-GMCT-NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAG 59
+NG +C N C N G + C C G++ GA C D +EC + P VC G C + G
Sbjct: 919 SNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGA-CVDRNECLEIPNVCSHGLCVDLQG 977
Query: 60 SYTCLCEPGF-APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC 118
SY C+C GF A C DVDEC C G C N+ GS+ C+C G+ T C
Sbjct: 978 SYQCICHNGFKASQDQTMCMDVDECERHP-CGNGTCKNTVGSYNCLCYPGFELTHNND-C 1035
Query: 119 VDVDECEE--QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACP 174
+D+DEC +VCRNGRC N GSF+C C G+ L+ DG+ C+ + SC
Sbjct: 1036 LDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGT 1095
Query: 175 AQGSE-LYAVLCPEGPS-KDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
Q E + +CP G K DINEC P C GSC N G++C+C PG+
Sbjct: 1096 CQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSD 1155
Query: 233 DGL-CRDIDE--C--DMHQSYCAGGQCRNTAGSFTCVCPE--GTRHEPELQLCRDIDECE 285
+G C D + C + C+ + NT + C C + G +LC DE
Sbjct: 1156 NGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKA-KCCCSKMPGEGWGDPCELCPKDDEVA 1214
Query: 286 GETETHYIESDYERGDIPPTFPTRTE----LASP--CDNGRCINTHGGFECECELGYVLD 339
+ Y G +P TR + L SP C NG+CINT G F CEC +GY LD
Sbjct: 1215 FQDLC-----PYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLD 1269
Query: 340 ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK 399
T RC+D S +G C ++ EC C+ +
Sbjct: 1270 YTGVRCVDTDECSIGNPCGNGTC----TNVIGSFECNCN--------------------E 1305
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
GF C D++ECA + LCA C+NT GSY C CP G L
Sbjct: 1306 GFEPGPMMNCEDINECAQNPLLCA-FRCMNTFGSYECTCPIGYAL 1349
Score = 233 bits (570), Expect = 9e-61
Identities = 150/468 (32%), Positives = 202/468 (43%), Gaps = 49/468 (10%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RGR-CRNTAGSYTCLCEPGF 69
C N G +EC C GY + +C+D+DEC + C RG C+N G++ C+C PG
Sbjct: 1332 CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGM 1391
Query: 70 APTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
A G C D +EC +C+ GRCVN GS++C C G++ +++ C+D
Sbjct: 1392 ARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDN------ 1445
Query: 128 RVCRNGRCHNTPGSFRCECLPGF-TLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCP 186
R G C C+ L C GWG C+ CP G+ Y +CP
Sbjct: 1446 ---RQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICP 1502
Query: 187 EGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMH 245
GP G DI+EC +P C +G C N +RC C GY D G C D+DEC
Sbjct: 1503 HGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQS 1562
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI--- 302
C C+NT GS+ C CP G + + + C+D+DEC+ + G
Sbjct: 1563 PKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCK 1621
Query: 303 -PPTFP-------TRTELASP---CD-NGRCINTHGGFECECELGYVLDATAQRCLD--- 347
PP F E S C G C NT G F CEC+ G+ LDAT C D
Sbjct: 1622 CPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDE 1681
Query: 348 ---NRRGSCWRRVVDGQCEAAAPELLLR----QECC----CSVGLAWGSXXXXXXXXXXX 396
N R + + G P+ ++ +C CS A GS
Sbjct: 1682 CDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYK 1741
Query: 397 XX--KGFA-KLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF+ + C DV+EC+ S C G C NT+G Y C CPPG
Sbjct: 1742 CACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPG 1788
Score = 227 bits (556), Expect = 5e-59
Identities = 140/448 (31%), Positives = 192/448 (42%), Gaps = 42/448 (9%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
N C N G + C C G+ +G C DVDEC +N +C G+C N G+Y C CE G
Sbjct: 486 NAQCVNTPGSYRCACSEGFTG--DGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMG 543
Query: 69 FAPTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
F P + + C D+DEC+ ++C G C N G F C+C+ GY T G C D+DEC +
Sbjct: 544 FTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADP 603
Query: 128 RVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
C NG C NTPG + C C P F L+ G C+ ++G GS
Sbjct: 604 INCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGV 663
Query: 188 GPSKDNGGADINECTAVP-GACPHGSCENLEPGYRCICDPGYHPD-ADGLCRDIDECDMH 245
G S+ + + + P CP + E C G+ P+ + DIDEC
Sbjct: 664 GVSRSSCCCSLGKAWGNPCETCP--PVNSTEYYTLCPGGEGFRPNPITIILEDIDECQEL 721
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
C GG C NT GSF C CP+G + ++C DIDEC + Y T
Sbjct: 722 PGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYN------T 775
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
T + P + +GG C +D R+ C+R CE
Sbjct: 776 LGNYTCICPP----EYMQVNGGHNC---------------MDMRKSFCYRSYNGTTCENE 816
Query: 366 APELLLRQECCC--SVGLAWGSXXXXXXXXXXXXXK-------GFA-KLDGATCRDVDEC 415
P + ++ CCC +VG AW K GF + D+DEC
Sbjct: 817 LPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDEC 876
Query: 416 ALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+CA G C+N GS+RC+CP G +
Sbjct: 877 KEIPGICANGVCINQIGSFRCECPTGFS 904
Score = 225 bits (551), Expect = 2e-58
Identities = 144/436 (33%), Positives = 201/436 (46%), Gaps = 55/436 (12%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDEC-AADSMCKGGRC 94
+D++EC+ P +C G+CRNT GS+ C C GFA C D+DEC + +C G C
Sbjct: 136 KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGIC 195
Query: 95 VNSEGSFQCVCEAGYRP-TATRGACVDVDECEEQ-RVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ GSF+C C GY C+D+DECE +CR G C NT GSF+C+C G L
Sbjct: 196 VNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHEL 255
Query: 153 SNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG-ADINECTAVPG 206
S C+ + L + Y C G + D G DI+EC + G
Sbjct: 256 SPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNG 315
Query: 207 ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
C C N E Y C C GY DG C DIDEC+ + C GGQC N G + C+C
Sbjct: 316 GC-DTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLC 374
Query: 266 PEGTRHEPELQLCRDIDECE--------GETETH------YIESDY--ERGDIPPTFPTR 309
+G +++ C D++EC+ GE E + + Y ++G T
Sbjct: 375 YDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDE 434
Query: 310 TEL-ASPCD-NGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAP 367
E+ A CD + C+N G F+C C G++ +C+D +D +C
Sbjct: 435 CEIGAHNCDMHASCLNIPGSFKCSCREGWI--GNGIKCID----------LD-ECSNGTH 481
Query: 368 ELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTC 427
+ + +C + G +GF DG TC DVDECA + LC G C
Sbjct: 482 QCSINAQCVNTPG-----------SYRCACSEGFTG-DGFTCSDVDECAENINLCENGQC 529
Query: 428 VNTDGSYRCDCPPGLT 443
+N G+YRC+C G T
Sbjct: 530 LNVPGAYRCECEMGFT 545
Score = 214 bits (523), Expect = 5e-55
Identities = 159/493 (32%), Positives = 213/493 (43%), Gaps = 76/493 (15%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGAL-CRDVDE---------CRDNPR----VCR 50
G C+ G C+N++G F CIC PGYE SE + + DE C + P +C
Sbjct: 1089 GSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCP 1148
Query: 51 RG--------RCRNTAGSYTCLC--EPGFAPTAAGYCADVDECAADSMCK---GGRCV-- 95
G RC +T S+ C E G + +C M G C
Sbjct: 1149 PGFVLSDNGRRCFDTRQSF-CFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELC 1207
Query: 96 --NSEGSFQCVCEAGYRPTAT-RGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFT 151
+ E +FQ +C G+ + DV+EC E +C NG+C NT GSFRCEC G+
Sbjct: 1208 PKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYN 1267
Query: 152 LSNDGRTCLGL-KLGWGVSCQ--ACP-AQGSELYAVLCPEG--PSKDNGGADINECTAVP 205
L G C+ + G C C GS + C EG P DINEC P
Sbjct: 1268 LDYTGVRCVDTDECSIGNPCGNGTCTNVIGS--FECNCNEGFEPGPMMNCEDINECAQNP 1325
Query: 206 GACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDEC--DMHQSYCAGGQCRNTAGSFT 262
C C N Y C C GY D +C+D+DEC +H G C+N G+F
Sbjct: 1326 LLCAF-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFM 1384
Query: 263 CVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCI 322
C+CP G P+ + C D +EC RT+ C+NGRC+
Sbjct: 1385 CICPPGMARRPDGEGCVDENEC------------------------RTK-PGICENGRCV 1419
Query: 323 NTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAP--ELLLRQECCCSVG 380
N G + CEC G+ ++ CLDNR+G C+ V+ C+ A+ L+ + ECCC G
Sbjct: 1420 NIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGG 1479
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKL-DGATC--RDVDECALSAELCAGGTCVNTDGSYRCD 437
WG K G T RD+DEC + LC G C+NT GS+RC
Sbjct: 1480 RGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCF 1539
Query: 438 CPPGLTLDSTGTA 450
C G T D +GT+
Sbjct: 1540 CKVGYTTDISGTS 1552
Score = 210 bits (513), Expect = 8e-54
Identities = 156/455 (34%), Positives = 193/455 (42%), Gaps = 75/455 (16%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C NG C N+ G FEC C G+E G C D++EC NP +C RC NT GSY C
Sbjct: 1284 GNPCGNGTCTNVIGSFECNCNEGFEPGPM-MNCEDINECAQNPLLCAF-RCMNTFGSYEC 1341
Query: 64 LCEPGFAPTA-AGYCADVDECAA---DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C G+A C D+DECA D +G C N G+F C+C G CV
Sbjct: 1342 TCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCV 1401
Query: 120 DVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
D +EC + +C NGRC N GS+RCEC GF S+ G CL + G C A
Sbjct: 1402 DENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGL---CFA------ 1452
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLE-PG---YRCICDPGYHPDADG 234
E+ +C S N +EC G CE PG Y+ IC G DG
Sbjct: 1453 EVLQTICQMASSSRNLVTK-SECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDG 1511
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
RDIDEC + + C GQC NT GSF C C G + C D+DEC
Sbjct: 1512 --RDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDEC---------- 1559
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCW 354
++ PC N C NT G ++C C GYVL + C D C
Sbjct: 1560 ---------------SQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTCKD--LDECQ 1601
Query: 355 RRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDE 414
+ C+ L C C GF + A C D +E
Sbjct: 1602 TK--QHNCQFLCVNTLGGFTCKCP--------------------PGFTQHHTA-CIDNNE 1638
Query: 415 CALSAELC-AGGTCVNTDGSYRCDCPPGLTLDSTG 448
C LC A G C NT GS+ C+C G +LD+TG
Sbjct: 1639 CGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATG 1673
Score = 200 bits (488), Expect = 8e-51
Identities = 144/457 (31%), Positives = 195/457 (42%), Gaps = 44/457 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C NI G + C+C G+ + + C DV+EC N +C G C NT GS+
Sbjct: 354 NPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFI 413
Query: 63 CLCEPGFA-PTAAGYCADVDEC--AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C+ G++ C DVDEC A + C+N GSF+C C G+ + C+
Sbjct: 414 CHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIK--CI 471
Query: 120 DVDECEE--QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-----KLGWGVSCQA 172
D+DEC + N +C NTPGS+RC C GFT DG TC + + + Q
Sbjct: 472 DLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVDECAENINLCENGQC 529
Query: 173 CPAQGSELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
G+ Y C G P+ D+ DI+EC + C G+C NL + CICD GY
Sbjct: 530 LNVPGA--YRCECEMGFTPASDSRSCQDIDEC-SFQNICVFGTCNNLPGMFHCICDDGYE 586
Query: 230 PD-ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET 288
D G C DIDEC C G C NT G + C CP + P C +D G
Sbjct: 587 LDRTGGNCTDIDEC-ADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGC--VDNRVGNC 643
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDN 348
Y++ RGD + TE+ C C C LG + C
Sbjct: 644 ---YLKFG-PRGD--GSLSCNTEIGVGVSRSSC--------C-CSLGKAWGNPCETCPPV 688
Query: 349 RRGSCWRRVVDGQCEAAAPELLLRQ---ECCCSVGLA-WGSXXXXXXXXXXXXXKG-FAK 403
+ G+ P ++ + EC GL G+ +G +
Sbjct: 689 NSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLS 748
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPP 440
D C D+DEC +C GTC NT G+Y C CPP
Sbjct: 749 EDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPP 785
Score = 195 bits (476), Expect = 2e-49
Identities = 131/409 (32%), Positives = 168/409 (41%), Gaps = 68/409 (16%)
Query: 65 CEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G A C DV+EC +C GRCVNS+GSF C C G T C+D+
Sbjct: 5 CPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRM 64
Query: 124 CEEQRVCRNGRC-HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
+ C H PG FR + C + WG C+ CP G++ Y
Sbjct: 65 EQCYLKWDEDECIHPVPGKFRMDA-----------CCCAVGAAWGTECEECPKPGTKEYE 113
Query: 183 VLCPEGPSKDNGG---------ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
LCP G N G DINEC A PG C +G C N ++C C+ G+ D +
Sbjct: 114 TLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDME 173
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE-PELQLCRDIDECEGETETH 291
C DIDEC + C G C NT GSF C C EG ++ C DIDECE
Sbjct: 174 ERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECE------ 227
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD---- 347
R L C G C+NT G F+C+C LG+ L + + C+D
Sbjct: 228 -----------------RNPLL--CRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINEC 268
Query: 348 ------NRRGSCWRRVVDGQCEA-----AAPE---LLLRQECCCSVGLAWGSXXXXXXXX 393
R G C + QC A P+ EC G
Sbjct: 269 SLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSY 328
Query: 394 XXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+G+A + DG +C D+DEC + ++C GG C N G YRC C G
Sbjct: 329 ECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDG 377
Score = 192 bits (469), Expect = 2e-48
Identities = 133/452 (29%), Positives = 194/452 (42%), Gaps = 46/452 (10%)
Query: 13 KNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
K+ + F+ +C G+ + S DV+EC ++P +C G+C NT GS+ C C G+
Sbjct: 1209 KDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNL 1268
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
G C D DEC+ + C G C N GSF+C C G+ P C D++EC + +
Sbjct: 1269 DYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMN-CEDINECAQNPLL 1327
Query: 131 RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGV-SCQACPAQGSEL---YAVLC 185
RC NT GS+ C C G+ L D + C L + G+ C++ L + +C
Sbjct: 1328 CAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCIC 1387
Query: 186 PEGPSK---DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDE 241
P G ++ G D NEC PG C +G C N+ YRC C+ G+ + G C D +
Sbjct: 1388 PPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQ 1447
Query: 242 ----CDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE-GETETHYIES 295
++ Q+ C RN C C G + +LC + + H
Sbjct: 1448 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGY 1507
Query: 296 DYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWR 355
+ DI + + C NG+CINT G F C C++GY D + C+D S
Sbjct: 1508 TTDGRDIDEC----KVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSP 1563
Query: 356 RVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDEC 415
+ + C+ +C C G + DG TC+D+DEC
Sbjct: 1564 KPCNYICKNTEGS----YQCSCPRGYV-------------------LQEDGKTCKDLDEC 1600
Query: 416 ALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
C CVNT G + C CPPG T T
Sbjct: 1601 QTKQHNCQ-FLCVNTLGGFTCKCPPGFTQHHT 1631
Score = 184 bits (448), Expect = 6e-46
Identities = 104/271 (38%), Positives = 130/271 (47%), Gaps = 13/271 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+CTNG C N G F C CK GY + G C D+DEC +P+ C C+NT GSY C C
Sbjct: 1523 LCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNY-ICKNTEGSYQCSC 1581
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DEC CVN+ G F C C G+ T AC+D +EC
Sbjct: 1582 PRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGF--TQHHTACIDNNEC 1639
Query: 125 EEQ-RVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSELY 181
Q +C G C NTPGSF CEC GF+L G C + + CQ Y
Sbjct: 1640 GSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGY 1699
Query: 182 AVLCPEGPSKD---NGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA-DGLCR 237
CP+G + N D NEC+ P AC SC N Y+C C G+ D C
Sbjct: 1700 RCGCPQGYIQHYQWNQCVDENECSN-PNACGSASCYNTLGSYKCACPSGFSFDQFSSACH 1758
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
D++EC ++ C G C NT G + C CP G
Sbjct: 1759 DVNECSSSKNPCNYG-CSNTEGGYLCGCPPG 1788
Score = 180 bits (439), Expect = 7e-45
Identities = 155/493 (31%), Positives = 197/493 (39%), Gaps = 86/493 (17%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTC 63
G+C+NG C N DG F C C GY G C D DEC NP C G C N GS+ C
Sbjct: 1244 GICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP--CGNGTCTNVIGSFEC 1301
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF P C D++ECA + + RC+N+ GS++C C GY + C D+DE
Sbjct: 1302 NCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDE 1361
Query: 124 CEE-QRVC--RNGRCHNTPGSFRCECLPGFTLSNDGRTCLG-----LKLGWGVSCQACPA 175
C E C R C N G+F C C PG DG C+ K G + +
Sbjct: 1362 CAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNI 1421
Query: 176 QGSELYAVLCPEGPSKDNGGADINE-----CTA--VPGACP-HGSCENLEPGYRCICDPG 227
GS Y C EG + G + + C A + C S NL C CD G
Sbjct: 1422 IGS--YRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGG 1479
Query: 228 Y---H-----------------PDADGLCRD---IDECDMHQSYCAGGQCRNTAGSFTCV 264
H P G D IDEC + + C GQC NT GSF C
Sbjct: 1480 RGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCF 1539
Query: 265 CPEGTRHEPELQLCRDIDEC-EGETETHYI----ESDYE----RGDIPPTFPTRTELASP 315
C G + C D+DEC + +YI E Y+ RG + +
Sbjct: 1540 CKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDE 1599
Query: 316 CDNGR------CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPEL 369
C + C+NT GGF C+C G+ TA C+DN +C + P L
Sbjct: 1600 CQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTA--CIDN-----------NEC-GSQPSL 1645
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAELCAGGTCV 428
C + G+ + +GF+ G C DVDEC C G C
Sbjct: 1646 ------CGAKGICQNT----PGSFSCECQRGFSLDATGLNCEDVDECD-GNHRCQHG-CQ 1693
Query: 429 NTDGSYRCDCPPG 441
N G YRC CP G
Sbjct: 1694 NILGGYRCGCPQG 1706
Score = 173 bits (421), Expect = 1e-42
Identities = 122/385 (31%), Positives = 169/385 (43%), Gaps = 53/385 (13%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE--CRDN--PRVCR-RGRCRN 56
T G+C NG C NI G + C C G++S S G C D + C +C+ RN
Sbjct: 1408 TKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRN 1467
Query: 57 TAGSYTCLCE--------------PGFA------PTAAGYCA---DVDEC-AADSMCKGG 92
C C+ PG A P GY D+DEC ++C G
Sbjct: 1468 LVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNG 1527
Query: 93 RCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTL 152
+C+N+ GSF+C C+ GY + +C+D+DEC + N C NT GS++C C G+ L
Sbjct: 1528 QCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVL 1587
Query: 153 SNDGRTCLGLK--LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGAC- 208
DG+TC L +CQ + CP G ++ + D NEC + P C
Sbjct: 1588 QEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCG 1647
Query: 209 PHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
G C+N + C C G+ DA GL C D+DECD + C G C+N G + C CP+
Sbjct: 1648 AKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR-CQHG-CQNILGGYRCGCPQ 1705
Query: 268 GTRHEPELQLCRDIDECE-----GETETHYIESDYE----RGDIPPTFPTR----TELAS 314
G + C D +EC G + Y+ G F + E +S
Sbjct: 1706 GYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSS 1765
Query: 315 ---PCDNGRCINTHGGFECECELGY 336
PC+ G C NT GG+ C C GY
Sbjct: 1766 SKNPCNYG-CSNTEGGYLCGCPPGY 1789
Score = 168 bits (408), Expect = 4e-41
Identities = 121/449 (26%), Positives = 178/449 (39%), Gaps = 63/449 (14%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
G+ + D+DEC++ P +C+ G C NT GS+ C C G+ + C D+DEC
Sbjct: 702 GFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECF 761
Query: 85 AD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFR 143
A +C G C N+ G++ C+C Y C+D+ R C+ +
Sbjct: 762 AHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDM---------RKSFCYRSYNGTT 812
Query: 144 CECLPGFTLSNDGRTC-LGLKLGWGVSCQACPAQGSELYAVLCPEGPS-----KDNGGAD 197
CE F ++ C + W C+ CP G+ + +C P D
Sbjct: 813 CENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVD 872
Query: 198 INECTAVPGACPHGSCENLEPGYRCICDPGY-HPDADGLCRDIDECDMHQSYC-AGGQCR 255
I+EC +PG C +G C N +RC C G+ + D +C DIDEC + C C
Sbjct: 873 IDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCI 932
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N+ GS+ C C G + P C D +EC E+ +
Sbjct: 933 NSPGSYRCECAAGFKLSPN-GACVDRNEC-------------------------LEIPNV 966
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLD----NR----RGSCWRRVVDGQCEA-AA 366
C +G C++ G ++C C G+ C+D R G+C V C
Sbjct: 967 CSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPG 1026
Query: 367 PELLLRQECC----CSVGLAW----GSXXXXXXXXXXXXXKGFAKL-DGATCRDVDECAL 417
EL +C CS G +G+ DG C D +EC
Sbjct: 1027 FELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVA 1086
Query: 418 SAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
C+ GTC N +GS+RC CPPG + S
Sbjct: 1087 LPGSCSPGTCQNLEGSFRCICPPGYEVKS 1115
Score = 167 bits (406), Expect = 7e-41
Identities = 128/472 (27%), Positives = 180/472 (38%), Gaps = 65/472 (13%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C G C N G F+C C GY + +C D+DEC +P VC G C NT G+YTC+
Sbjct: 723 GLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCI 782
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C P + G+ C D+ + C S C E + T C
Sbjct: 783 CPPEYMQVNGGHNCMDM---------RKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVG 833
Query: 124 CEEQRVCRNGRCHNTPGS--FRCEC--LPGFTLSNDGRTCLGL---KLGWGVSCQACPAQ 176
+ C C TPG+ F+ C +PGFT + + K G+
Sbjct: 834 KAWNKPCE--PC-PTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCIN 890
Query: 177 GSELYAVLCPEGPSKDN---GGADINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDA 232
+ CP G S ++ DI+EC+ C + C N YRC C G+
Sbjct: 891 QIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSP 950
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE----GET 288
+G C D +EC + C+ G C + GS+ C+C G + + +C D+DECE G
Sbjct: 951 NGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNG 1010
Query: 289 ETHYIESDY-----------ERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYV 337
Y D + C NGRC N G F+C C GY
Sbjct: 1011 TCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYE 1070
Query: 338 LDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXXXXX 396
L + C+D C + G C + L C C G
Sbjct: 1071 LTPDGKNCIDT--NEC--VALPGSCSPGTCQNLEGSFRCICPPGY--------------- 1111
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
++ C D++EC +C G+C NT G ++C CPPG L G
Sbjct: 1112 ------EVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNG 1157
Score = 157 bits (382), Expect = 6e-38
Identities = 85/235 (36%), Positives = 116/235 (49%), Gaps = 11/235 (4%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
N ICKN +G ++C C GY +G C+D+DEC+ C+ C NT G +TC C PG
Sbjct: 1567 NYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF-LCVNTLGGFTCKCPPG 1625
Query: 69 FAPTAAGYCADVDECAAD-SMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
F C D +EC + S+C G C N+ GSF C C+ G+ AT C DVDEC+
Sbjct: 1626 FTQHHTA-CIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDG 1684
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGS-ELYAVL 184
C++G C N G +RC C G+ C+ + +C + + Y
Sbjct: 1685 NHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCA 1743
Query: 185 CPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
CP G S D + D+NEC++ C +G C N E GY C C PGY+ G C
Sbjct: 1744 CPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGYYRVGQGHC 1797
Score = 149 bits (361), Expect = 2e-35
Identities = 123/398 (30%), Positives = 169/398 (42%), Gaps = 47/398 (11%)
Query: 68 GFAPTAAGYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G P+ DV+EC + +C G+C+N++GSF+C C GY T CVD DEC
Sbjct: 1224 GTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI 1283
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFT---LSN--DGRTCLGLKLGWGVSCQACPAQGSELY 181
C NG C N GSF C C GF + N D C L C GS Y
Sbjct: 1284 GNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMN--TFGS--Y 1339
Query: 182 AVLCPEGPS--KDNGGA-DINECTAVPGACPHGS--CENLEPGYRCICDPGY--HPDADG 234
CP G + +D D++EC C C+NL + CIC PG PD +G
Sbjct: 1340 ECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEG 1399
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
C D +EC C G+C N GS+ C C EG + C +D +G ++
Sbjct: 1400 -CVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTEC--LDNRQGLCFAEVLQ 1456
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQR---CLDNRRG 351
+ + T++E CD GR G+ +CEL L TAQ C
Sbjct: 1457 TICQMASSSRNLVTKSECC--CDGGR------GWGHQCEL-CPLPGTAQYKKICPHGPGY 1507
Query: 352 SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK-LDGATCR 410
+ R +D +C+ P L +C ++G G+ + G +C
Sbjct: 1508 TTDGRDID-ECKVM-PNLCTNGQCINTMG-----------SFRCFCKVGYTTDISGTSCI 1554
Query: 411 DVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
D+DEC+ S + C C NT+GSY+C CP G L G
Sbjct: 1555 DLDECSQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDG 1591
Score = 137 bits (332), Expect = 7e-32
Identities = 124/441 (28%), Positives = 164/441 (37%), Gaps = 59/441 (13%)
Query: 32 EGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAG-YCADVDECAADSMCK 90
+G C DV+EC P VC GRC N+ GS+ C C G G C D+
Sbjct: 13 KGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWD 72
Query: 91 GGRCVNS-EGSFQ---CVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCEC 146
C++ G F+ C C G C E + +C G G +
Sbjct: 73 EDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRG----DV 128
Query: 147 LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG---PSKDNGGADINECTA 203
L G D C G + GS + C G ++ DI+EC
Sbjct: 129 LTGRPFYKDINECKAFP-GMCTYGKCRNTIGS--FKCRCNSGFALDMEERNCTDIDECRI 185
Query: 204 VPGACPHGSCENLEPGYRCICDPGYHPDADGL--CRDIDECDMHQSYCAGGQCRNTAGSF 261
P C G C N + C C GY + C DIDEC+ + C GG C NT GSF
Sbjct: 186 SPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSF 245
Query: 262 TCVCPEGTRHEPELQLCRDIDECE------GETETHYIESDYERGDIP--PTFPTR---T 310
C CP G P + C DI+EC + + Y+ P P R T
Sbjct: 246 QCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCT 305
Query: 311 E------LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVD-GQCE 363
+ + CD +C N+ G +EC C GY L + C D + D GQC
Sbjct: 306 DIDECMIMNGGCDT-QCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCT 364
Query: 364 AAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA 423
E C C G A +D TC DV+EC L++ +C
Sbjct: 365 NIPGE----YRCLCYDGF-------------------MASMDMKTCIDVNECDLNSNICM 401
Query: 424 GGTCVNTDGSYRCDCPPGLTL 444
G C NT GS+ C C G ++
Sbjct: 402 FGECENTKGSFICHCQLGYSV 422
Score = 120 bits (288), Expect = 1e-26
Identities = 57/159 (35%), Positives = 77/159 (48%), Gaps = 3/159 (1%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
GIC+N G F C C+ G+ + G C DVDEC N R C+ G C+N G Y C C G+
Sbjct: 1650 GICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR-CQHG-CQNILGGYRCGCPQGY 1707
Query: 70 APTAA-GYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
C D +EC+ + C C N+ GS++C C +G+ AC DV+EC +
Sbjct: 1708 IQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSK 1767
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWG 167
N C NT G + C C PG+ G G+ G
Sbjct: 1768 NPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKG 1806
Score = 94.7 bits (225), Expect = 6e-19
Identities = 51/142 (35%), Positives = 65/142 (45%), Gaps = 12/142 (8%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C NGRC+N+ G F CEC G LD T + CLD R C+ + + +C P C
Sbjct: 30 CPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDAC 89
Query: 376 CCSVGLAWGSX-------XXXXXXXXXXXXKGFAKL-DGATCR----DVDECALSAELCA 423
CC+VG AWG+ GFA D T R D++EC +C
Sbjct: 90 CCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCT 149
Query: 424 GGTCVNTDGSYRCDCPPGLTLD 445
G C NT GS++C C G LD
Sbjct: 150 YGKCRNTIGSFKCRCNSGFALD 171
Score = 69.7 bits (163), Expect = 2e-11
Identities = 26/50 (52%), Positives = 35/50 (70%)
Query: 399 KGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+G A++ G TC DV+EC + +C G CVN+ GS+ C+CP GLTLD TG
Sbjct: 7 RGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTG 56
Score = 64.5 bits (150), Expect = 7e-10
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
+N C + C N G ++C C G+ + C DV+EC + C G C NT G Y
Sbjct: 1723 SNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGY 1781
Query: 62 TCLCEPGFAPTAAGYC 77
C C PG+ G+C
Sbjct: 1782 LCGCPPGYYRVGQGHC 1797
>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
protein-4 protein.
Length = 1587
Score = 259 bits (634), Expect = 2e-68
Identities = 163/448 (36%), Positives = 201/448 (44%), Gaps = 62/448 (13%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G C+N G F C+C GY++ GA C+DVDEC +P +C RG C+N GS+ C+C
Sbjct: 603 CDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGGCKNLPGSFRCVCP 662
Query: 67 PGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC- 124
GF +A DVDECA + C GRC N+ GSF C C AG+R C DVDEC
Sbjct: 663 AGFRGSACE--EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECA 720
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSC--QACPAQGSELY 181
C GRC NT GSF+C C GF + G C + + ++C Q C
Sbjct: 721 RSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQ 780
Query: 182 AVLCPEGPSKDNGG-ADINECTA-VPGACPHGSCENLEPGYRCICDPGYHPDA--DGLCR 237
CP G G D++EC++ P PHG C N E +RC C PGY + G C
Sbjct: 781 CRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCA 840
Query: 238 DIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
D++EC + +C G+C NT GSF C C G R P C D+DEC E
Sbjct: 841 DVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEE--------- 890
Query: 297 YERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRR 356
D+ C +G C NT G FEC C G+ CLD
Sbjct: 891 ----DL-------------CQSGICTNTDGSFECICPPGHRAGPDLASCLD--------- 924
Query: 357 VVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDEC- 415
VD +C P L Q C S G G+ TC DVDEC
Sbjct: 925 -VD-ECRERGPALCGSQRCENSPG---------SYRCVRDCDPGYHAGPEGTCDDVDECQ 973
Query: 416 ALSAELCAGGTCVNTDGSYRCD--CPPG 441
E+C C NT GSYRC C PG
Sbjct: 974 EYGPEICGAQRCENTPGSYRCTPACDPG 1001
Score = 250 bits (611), Expect = 1e-65
Identities = 166/480 (34%), Positives = 202/480 (42%), Gaps = 62/480 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C + G+ C C G+ +G C DVDECR P C GRC N+ GS+
Sbjct: 515 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 574
Query: 63 CLCEPGF-APTAAGYCADVDEC-AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C+C PGF A A C DVDEC C GRC N+ GSF CVC AGY+ +C D
Sbjct: 575 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 634
Query: 121 VDEC-EEQRVCRNGRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQ 176
VDEC + +C G C N PGSFRC C GF D C G C
Sbjct: 635 VDECTQSPGLCGRGGCKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPG--RCDNT 692
Query: 177 GSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ CP G GA D++EC P C +G CEN E ++C+C G+ P+
Sbjct: 693 AGSFHCA-CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTA 751
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTC-VCPEGTRHEPELQLCRDIDECEGET--- 288
G C D+DEC+ H + C G +C N+ GSF C CP G H C D+DEC
Sbjct: 752 GSECEDVDECENHLA-CPGQECVNSPGSFQCRTCPSG--HHLHRGRCTDVDECSSGAPPC 808
Query: 289 --ETHYIESDYE-RGDIPPTFPTRTELASPC-------------DNGRCINTHGGFECEC 332
H ++ R P + + PC +G C+NT G F C C
Sbjct: 809 GPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC 868
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
GY CLD S G C EC C G G
Sbjct: 869 APGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSF----ECICPPGHRAGP------- 917
Query: 393 XXXXXXKGFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC--DCPPGLTLDSTGT 449
D A+C DVDEC LC C N+ GSYRC DC PG GT
Sbjct: 918 ------------DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT 965
Score = 233 bits (570), Expect = 9e-61
Identities = 152/464 (32%), Positives = 198/464 (42%), Gaps = 58/464 (12%)
Query: 9 NGICKNIDGGFECICKPGYE--SGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
+G C N +G F C C PGY SG G C DV+EC + G C NT GS+ C C
Sbjct: 811 HGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLEGDFCFPHGECLNTDGSFACTCA 869
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
PG+ P G C DVDEC+ + +C+ G C N++GSF+C+C G+R +C+DVDEC
Sbjct: 870 PGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECR 929
Query: 126 EQ--RVCRNGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ----- 176
E+ +C + RC N+PGS+RC +C PG+ +G TC + + C AQ
Sbjct: 930 ERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENT 988
Query: 177 -GSELYAVLCPEG--PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
GS C G P+ G D++EC H C+NL ++C+CD GY D
Sbjct: 989 PGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARD 1048
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH-EPELQLCRDIDECEGETETH 291
G C D++EC+ Q C C N GSF CVCP +P C T
Sbjct: 1049 GRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRC-----VPPRTSVG 1103
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDN--R 349
+ + P P R P G C Y D A DN
Sbjct: 1104 MSPGSQPQAPVSPVLPARPP-PPPLSRRPRKPRKGPVGSGCRECY-FDTAAPDACDNILA 1161
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS---------XXXXXXXXXXXXXKG 400
R W QECCC+VG WGS +G
Sbjct: 1162 RNVTW------------------QECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRG 1203
Query: 401 FAKLDG--ATCRDVDECAL-SAELCAGGTCVNTDGSYRCDCPPG 441
+ G + RDVDEC L ++C G CVNT Y C C G
Sbjct: 1204 YLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNG 1247
Score = 230 bits (563), Expect = 7e-60
Identities = 147/424 (34%), Positives = 180/424 (42%), Gaps = 47/424 (11%)
Query: 42 CRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAG-YCADVDEC-AADSMCKGGRCVNSEG 99
C+ NP+VC GRC + YTC C+ GF + G C DVDEC C GRC NS G
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 571
Query: 100 SFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
SF+CVC G+R C+DVDEC C GRC NTPGSF C C G+ + G +
Sbjct: 572 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 631
Query: 159 CLGLKLGWGVSCQACPAQGSE----LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCE 214
C + S C G + + +CP G D++EC P C G C+
Sbjct: 632 CQDVD-ECTQSPGLCGRGGCKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCD 690
Query: 215 NLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEP 273
N + C C G+ G C+D+DEC C G+C NT GSF CVCP G +
Sbjct: 691 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT 750
Query: 274 ELQLCRDIDECEGETETHYIESDYERGDIP-PTFPTRTEL--------------ASPC-D 317
C D+DECE E G T P+ L A PC
Sbjct: 751 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGP 810
Query: 318 NGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCC 377
+G C NT G F C C GY R R G C A L + C
Sbjct: 811 HGHCTNTEGSFRCSCAPGY-------RAPSGRPGPC-----------ADVNECLEGDFCF 852
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCD 437
G + G GA+C DVDEC+ +LC G C NTDGS+ C
Sbjct: 853 PHGECLNTDGSFACTCAPGYRPG---PRGASCLDVDECS-EEDLCQSGICTNTDGSFECI 908
Query: 438 CPPG 441
CPPG
Sbjct: 909 CPPG 912
Score = 198 bits (482), Expect = 4e-50
Identities = 148/440 (33%), Positives = 185/440 (42%), Gaps = 88/440 (20%)
Query: 6 MCTNGICKNIDGGFECI--CKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYT 62
+C + C+N G + C+ C PGY +G EG C DVDEC++ P +C RC NT GSY
Sbjct: 935 LCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYR 993
Query: 63 CL--CEPGFAPTAAGYCADVDECAADSMCKGGR-CVNSEGSFQCVCEAGYRPTATRGACV 119
C C+PG+ PT G C DVDEC S C C N GSFQC+C+ GY CV
Sbjct: 994 CTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV 1053
Query: 120 DVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT--CLGLKLGWGVS------- 169
DV+ECE Q VC C N GSF C C P D T C+ + G+S
Sbjct: 1054 DVNECETLQGVCGAALCENVEGSFLCVC-PNSPEEFDPMTGRCVPPRTSVGMSPGSQPQA 1112
Query: 170 --CQACPAQGSELYAVLCPEGPSKDNGGADINEC---TAVPGACPHGSCENLE------- 217
PA+ P P K G+ EC TA P AC + N+
Sbjct: 1113 PVSPVLPARPPPPPLSRRPRKPRKGPVGSGCRECYFDTAAPDACDNILARNVTWQECCCT 1172
Query: 218 --------------PG-----YRCICDPG---YHPDAD-GLCRDIDECDMHQSY-CAGGQ 253
PG Y+ +C G P D L RD+DEC + + C G
Sbjct: 1173 VGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV 1232
Query: 254 CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELA 313
C NTA ++C C G + + C D DEC E
Sbjct: 1233 CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPA----------------------- 1269
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRC-------LDNRRGSCWRRV-VDGQC-EA 364
C+ GRC+NT G + C CE VLD + +RC LD+ G CW+ V D C
Sbjct: 1270 --CEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHP 1327
Query: 365 AAPELLLRQECCCSVGLAWG 384
ECCC G AWG
Sbjct: 1328 RLDRQATYTECCCLYGEAWG 1347
Score = 190 bits (464), Expect = 7e-48
Identities = 128/375 (34%), Positives = 162/375 (43%), Gaps = 65/375 (17%)
Query: 88 MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCEC 146
+C GRC++ + C C++G+R + C+DVDEC C GRC N+PGSFRC C
Sbjct: 518 VCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVC 577
Query: 147 LPGFTLSNDGRTCLGLKLGWGVS--CQACPAQGSE-LYAVLCPEGPSKDNGGA---DINE 200
PGF CL + V C + + + +CP G GA D++E
Sbjct: 578 GPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDE 637
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCAGGQCRNTAG 259
CT PG C G C+NL +RC+C G+ A C D+DEC C G+C NTAG
Sbjct: 638 CTQSPGLCGRGGCKNLPGSFRCVCPAGFRGSA---CEEDVDECAQEPPPCGPGRCDNTAG 694
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG 319
SF C CP G R C+D+DEC PP PC G
Sbjct: 695 SFHCACPAGFRSRGPGAPCQDVDECARS---------------PP----------PCTYG 729
Query: 320 RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCE--AAAPELLLRQECCC 377
RC NT G F+C C +G+ + C D VD +CE A P QEC
Sbjct: 730 RCENTEGSFQCVCPMGFQPNTAGSECED----------VD-ECENHLACPG----QECVN 774
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG-GTCVNTDGSYRC 436
S G S +G C DVDEC+ A C G C NT+GS+RC
Sbjct: 775 SPG----SFQCRTCPSGHHLHRG-------RCTDVDECSSGAPPCGPHGHCTNTEGSFRC 823
Query: 437 DCPPGLTLDSTGTAP 451
C PG S P
Sbjct: 824 SCAPGYRAPSGRPGP 838
Score = 179 bits (435), Expect = 2e-44
Identities = 127/377 (33%), Positives = 173/377 (45%), Gaps = 42/377 (11%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCL 64
+C +GIC N DG FECIC PG+ +G + A C DVDECR+ P +C RC N+ GSY C+
Sbjct: 892 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 951
Query: 65 --CEPGFAPTAAGYCADVDECA--ADSMCKGGRCVNSEGSFQC--VCEAGYRPTATRGAC 118
C+PG+ G C DVDEC +C RC N+ GS++C C+ GY+PT G C
Sbjct: 952 RDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PGGGC 1010
Query: 119 VDVDECEEQRVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSCQACP 174
DVDEC + C + C N PGSF+C C G+ + DGR C+ + + GV C A
Sbjct: 1011 QDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGV-CGAAL 1069
Query: 175 AQGSE-LYAVLCPEGPSKDN--GGADINECTAV---PGACPHGSCENLEPG-------YR 221
+ E + +CP P + + G + T+V PG+ P + P R
Sbjct: 1070 CENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSVGMSPGSQPQAPVSPVLPARPPPPPLSR 1129
Query: 222 CICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI 281
P P G CR+ C RN C C G E CR I
Sbjct: 1130 RPRKPRKGPVGSG-CRECYFDTAAPDACDNILARNVTWQ-ECCCTVG---EGWGSGCR-I 1183
Query: 282 DECEG-ETETHYIESDYERGDIPPT--FPTRTEL-------ASPCDNGRCINTHGGFECE 331
+C G ET + + RG + P+ R ++ C +G C+NT G+ C
Sbjct: 1184 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1243
Query: 332 CELGYVLDATAQRCLDN 348
C GY C+DN
Sbjct: 1244 CSNGYYYHTQRLECIDN 1260
Score = 126 bits (304), Expect = 2e-28
Identities = 94/296 (31%), Positives = 112/296 (37%), Gaps = 45/296 (15%)
Query: 174 PAQGSELYAVLCPE--GPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
P G EL P GP G C P C G C + GY C CD G+
Sbjct: 483 PRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLS 542
Query: 232 ADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
G C D+DEC CA G+C N+ GSF CVC G R P C D+DEC
Sbjct: 543 PQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECH----- 597
Query: 291 HYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD--- 347
+PP PCD GRC NT G F C C GY C D
Sbjct: 598 ----------RVPP----------PCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDE 637
Query: 348 --NRRGSCWR---RVVDGQCEAAAPELLLRQEC------CCSVGLAWGSXXXXXXXXXXX 396
G C R + + G P C C G
Sbjct: 638 CTQSPGLCGRGGCKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFH 697
Query: 397 XX--KGF-AKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
GF ++ GA C+DVDECA S C G C NT+GS++C CP G ++ G+
Sbjct: 698 CACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGS 753
Score = 120 bits (290), Expect = 8e-27
Identities = 85/277 (30%), Positives = 113/277 (40%), Gaps = 22/277 (7%)
Query: 3 NGGMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C + +C+N+ G F+C+C GYE +G C DV+EC VC C N GS+
Sbjct: 1018 NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSF 1077
Query: 62 TCLC--EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C+C P G C V + M G + + V A P
Sbjct: 1078 LCVCPNSPEEFDPMTGRC--VPPRTSVGMSPGSQ---PQAPVSPVLPARPPPPPLSRRPR 1132
Query: 120 DVDECEEQRVCRNGRCH-NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC--QACPAQ 176
+ CR C+ +T C+ + ++ C + GWG C Q CP
Sbjct: 1133 KPRKGPVGSGCRE--CYFDTAAPDACDNILARNVTWQ-ECCCTVGEGWGSGCRIQQCPGT 1189
Query: 177 GSELYAVLCPEG-----PSKDNG-GADINECTAVPG-ACPHGSCENLEPGYRCICDPGYH 229
+ Y LCP G PS D D++EC C G C N PGY C C GY+
Sbjct: 1190 ETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY 1249
Query: 230 PDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
L C D DEC + C GG+C NT GS+ C C
Sbjct: 1250 YHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1286
Score = 90.2 bits (214), Expect = 1e-17
Identities = 58/157 (36%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Query: 34 ALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADVDECA-ADSMCK 90
+L RDVDEC+ +VC+ G C NTA Y+C C G + T C D DECA + C+
Sbjct: 1212 SLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACE 1271
Query: 91 GGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN-GRCHNTPGSFRCECLPG 149
GGRCVN+ GS+ C CE ++ CV E Q + N G C G+ P
Sbjct: 1272 GGRCVNTVGSYHCTCEPPLVLDGSQRRCV---SNESQSLDDNLGVCWQEVGADLVCSHPR 1328
Query: 150 FTLSNDGRTCLGL-KLGWGVSCQACPAQGSELYAVLC 185
C L WG+ C CPAQ S+ + LC
Sbjct: 1329 LDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC 1365
Score = 81.0 bits (191), Expect = 8e-15
Identities = 44/145 (30%), Positives = 60/145 (41%), Gaps = 5/145 (3%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C GF G C DVDECA C+ G C N+ G + CVC G+ ++R +C+
Sbjct: 307 CPTGFE-RVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 365
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
E + G C C ++ C + WG CQ CP GSE + +
Sbjct: 366 SEAK----GPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREI 421
Query: 185 CPEGPSKDNGGADINECTAVPGACP 209
CP GP +D+ T G P
Sbjct: 422 CPAGPGYHYSASDLRYNTRPLGQEP 446
Score = 79.4 bits (187), Expect = 2e-14
Identities = 46/117 (39%), Positives = 57/117 (48%), Gaps = 10/117 (8%)
Query: 53 RCRNTAGSYTCLCEPGFAPTAAGYCAD------VDECAADSMCKGGRCVNSEGSFQCVCE 106
R R+T S+ EP + AG A+ +EC C RCV F C C
Sbjct: 1464 RSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNDRCVRVPEGFTCRCF 1523
Query: 107 AGYRPTATRGACVDVDECEEQR----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
GYR TR ACVD++EC+E +C N RC NT GSFRC C PGF ++ C
Sbjct: 1524 DGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 69.7 bits (163), Expect = 2e-11
Identities = 38/108 (35%), Positives = 50/108 (46%), Gaps = 13/108 (12%)
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK----------- 399
G C+R + G+C + P L ++ CC GLAWG +
Sbjct: 250 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPT 309
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
GF +++G +C DVDECA C G C NT G Y C CP G LDS+
Sbjct: 310 GFERVNG-SCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSS 355
Score = 66.5 bits (155), Expect = 2e-10
Identities = 29/69 (42%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPR---VCRRGRCRNTAGSYTC 63
CTN C + GF C C GY C D++EC + +C RC NT GS+ C
Sbjct: 1506 CTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1565
Query: 64 LCEPGFAPT 72
+C PGFAPT
Sbjct: 1566 ICRPGFAPT 1574
Score = 65.7 bits (153), Expect = 3e-10
Identities = 29/75 (38%), Positives = 41/75 (54%), Gaps = 6/75 (8%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNR-----RGSCWRRVVDGQCEAAAPELL 370
C +G C NT GG+ C C G++LD++ C+ +G C+R + DG C +
Sbjct: 330 CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNI 389
Query: 371 LRQECCCS-VGLAWG 384
+Q CCCS VG AWG
Sbjct: 390 TKQICCCSRVGKAWG 404
Score = 58.8 bits (136), Expect = 4e-08
Identities = 35/93 (37%), Positives = 43/93 (46%), Gaps = 10/93 (10%)
Query: 147 LPGFTLSNDGRTCLGLKLGWGV-SCQACPAQGSELYAVLCPEGP-----SKDNGGA-DIN 199
LPG L C G L WGV CQ C + V P+GP + NG D++
Sbjct: 265 LPG--LRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVD 322
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
EC A G C HG C N GY C+C G+ D+
Sbjct: 323 EC-ATGGRCQHGECANTRGGYTCVCPDGFLLDS 354
Score = 56.0 bits (129), Expect = 3e-07
Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQS---YCAGG 252
+ EC + G C + C + G+ C C GY D + C DI+ECD ++ C
Sbjct: 1496 EAEECGILDG-CTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 253 QCRNTAGSFTCVCPEG--TRHEP 273
+C NT GSF C+C G H+P
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQP 1577
Score = 52.0 bits (119), Expect = 4e-06
Identities = 22/39 (56%), Positives = 23/39 (58%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
C D DECA C GG CVNT GSY C C P L LD +
Sbjct: 1257 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGS 1295
Score = 49.6 bits (113), Expect = 2e-05
Identities = 22/47 (46%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
C G+E + C DVDEC R C+ G C NT G YTC+C GF
Sbjct: 307 CPTGFERVNGS--CEDVDECATGGR-CQHGECANTRGGYTCVCPDGF 350
Score = 48.8 bits (111), Expect = 4e-05
Identities = 20/45 (44%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C G+ +G C D+DEC C G+C NT G +TCVCP+G
Sbjct: 307 CPTGFER-VNGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDG 349
Score = 44.4 bits (100), Expect = 8e-04
Identities = 32/113 (28%), Positives = 42/113 (37%), Gaps = 25/113 (22%)
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDY 297
+ +EC + C +C FTC C +G R + C DI+EC+
Sbjct: 1496 EAEECGILDG-CTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECD------------ 1542
Query: 298 ERGDIPPTFPTRTELASP-CDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
E ASP C N RC+NT G F C C G+ C R
Sbjct: 1543 -----------EAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1584
Score = 43.2 bits (97), Expect = 0.002
Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 3/36 (8%)
Query: 409 CRDVDEC---ALSAELCAGGTCVNTDGSYRCDCPPG 441
C D++EC ++ LC C+NTDGS+RC C PG
Sbjct: 1535 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1570
Score = 37.9 bits (84), Expect = 0.073
Identities = 12/22 (54%), Positives = 15/22 (68%)
Query: 6 MCTNGICKNIDGGFECICKPGY 27
+C N C N DG F CIC+PG+
Sbjct: 1550 LCVNARCLNTDGSFRCICRPGF 1571
Score = 37.1 bits (82), Expect = 0.13
Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 4/55 (7%)
Query: 4 GGMCTNGICKNIDGGFECICKPGY--ESGSEGALCRDVDECRDNP--RVCRRGRC 54
GG C +G C N GG+ C+C G+ +S + + V P RV R G C
Sbjct: 327 GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGC 381
Score = 34.3 bits (75), Expect = 0.90
Identities = 13/44 (29%), Positives = 19/44 (43%)
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL 162
++ +EC C N RC P F C C G+ L C+ +
Sbjct: 1495 LEAEECGILDGCTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDI 1538
>AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth
factor-beta binding protein 4L protein.
Length = 1624
Score = 258 bits (633), Expect = 2e-68
Identities = 163/448 (36%), Positives = 201/448 (44%), Gaps = 62/448 (13%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G C+N G F C+C GY++ GA C+DVDEC +P +C RG C+N GS+ C+C
Sbjct: 640 CDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCP 699
Query: 67 PGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC- 124
GF +A DVDECA + C GRC N+ GSF C C AG+R C DVDEC
Sbjct: 700 AGFRGSACE--EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECA 757
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSC--QACPAQGSELY 181
C GRC NT GSF+C C GF + G C + + ++C Q C
Sbjct: 758 RSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQ 817
Query: 182 AVLCPEGPSKDNGG-ADINECTA-VPGACPHGSCENLEPGYRCICDPGYHPDA--DGLCR 237
CP G G D++EC++ P PHG C N E +RC C PGY + G C
Sbjct: 818 CRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCA 877
Query: 238 DIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
D++EC + +C G+C NT GSF C C G R P C D+DEC E
Sbjct: 878 DVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEE--------- 927
Query: 297 YERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRR 356
D+ C +G C NT G FEC C G+ CLD
Sbjct: 928 ----DL-------------CQSGICTNTDGSFECICPPGHRAGPDLASCLD--------- 961
Query: 357 VVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDEC- 415
VD +C P L Q C S G G+ TC DVDEC
Sbjct: 962 -VD-ECRERGPALCGSQRCENSPG---------SYRCVRDCDPGYHAGPEGTCDDVDECQ 1010
Query: 416 ALSAELCAGGTCVNTDGSYRCD--CPPG 441
E+C C NT GSYRC C PG
Sbjct: 1011 EYGPEICGAQRCENTPGSYRCTPACDPG 1038
Score = 252 bits (616), Expect = 3e-66
Identities = 167/480 (34%), Positives = 203/480 (42%), Gaps = 62/480 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C + G+ C C G+ +G C DVDECR P C GRC N+ GS+
Sbjct: 552 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 611
Query: 63 CLCEPGF-APTAAGYCADVDEC-AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C+C PGF A A C DVDEC C GRC N+ GSF CVC AGY+ +C D
Sbjct: 612 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 671
Query: 121 VDEC-EEQRVCRNGRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQ 176
VDEC + +C G C N PGSFRC C GF D C G C
Sbjct: 672 VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPG--RCDNT 729
Query: 177 GSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ CP G GA D++EC P C +G CEN E ++C+C G+ P+A
Sbjct: 730 AGSFHCA-CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAA 788
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTC-VCPEGTRHEPELQLCRDIDECEGET--- 288
G C D+DEC+ H + C G +C N+ GSF C CP G H C D+DEC
Sbjct: 789 GSECEDVDECENHLA-CPGQECVNSPGSFQCRACPSG--HHLHRGRCTDVDECSSGAPPC 845
Query: 289 --ETHYIESDYE-RGDIPPTFPTRTELASPC-------------DNGRCINTHGGFECEC 332
H ++ R P + + PC +G C+NT G F C C
Sbjct: 846 GPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC 905
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
GY CLD S G C EC C G G
Sbjct: 906 APGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSF----ECICPPGHRAGP------- 954
Query: 393 XXXXXXKGFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC--DCPPGLTLDSTGT 449
D A+C DVDEC LC C N+ GSYRC DC PG GT
Sbjct: 955 ------------DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT 1002
Score = 231 bits (564), Expect = 5e-60
Identities = 169/486 (34%), Positives = 215/486 (44%), Gaps = 56/486 (11%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCLC 65
C C N G F+C P G C DVDEC C G C NT GS+ C C
Sbjct: 804 CPGQECVNSPGSFQCRACPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSC 862
Query: 66 EPGF-APTAA-GYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
PG+ AP+ G CADV+EC C G C+N++GSF C C GYRP +C+DVD
Sbjct: 863 APGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVD 922
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL--------GLKLGWGVSCQACP 174
EC E+ +C++G C NT GSF C C PG D +CL G L C+ P
Sbjct: 923 ECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP 982
Query: 175 AQGSELYAVLCPEGPSKDNGGA--DINECTAV-PGACPHGSCENLEPGYRC--ICDPGYH 229
GS C G G D++EC P C CEN YRC CDPGY
Sbjct: 983 --GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ 1040
Query: 230 PDADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG-E 287
P G C+D+DEC ++S+C A C+N GSF C+C +G + + C D++ECE +
Sbjct: 1041 PTPGGGCQDVDEC-RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQ 1099
Query: 288 TETHYIESDYERGDIPPTFPTRTELASPCDNGRCI--NTHGGF----ECECELGYVLDAT 341
+ G P E P GRC+ T G + + VL A
Sbjct: 1100 GVCGAALCENVEGSFLCVCPNSPEEFDPM-TGRCVPPRTSAGMFPGSQPQAPASPVLPAR 1158
Query: 342 AQRCLDNRRGSCWRRVVDG----QC--EAAAPE----LLLR----QECCCSVGLAWGS-- 385
RR S R+ G +C + AAP+ +L R QECCC+VG WGS
Sbjct: 1159 PPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGC 1218
Query: 386 -------XXXXXXXXXXXXXKGFAKLDG--ATCRDVDECAL-SAELCAGGTCVNTDGSYR 435
+G+ G + RDVDEC L ++C G CVNT Y
Sbjct: 1219 RIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYS 1278
Query: 436 CDCPPG 441
C C G
Sbjct: 1279 CYCSNG 1284
Score = 229 bits (559), Expect = 2e-59
Identities = 149/428 (34%), Positives = 183/428 (42%), Gaps = 55/428 (12%)
Query: 42 CRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAG-YCADVDEC-AADSMCKGGRCVNSEG 99
C+ NP+VC GRC + YTC C+ GF + G C DVDEC C GRC NS G
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 608
Query: 100 SFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
SF+CVC G+R C+DVDEC C GRC NTPGSF C C G+ + G +
Sbjct: 609 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 668
Query: 159 CLGLK--------LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH 210
C + G G +C+ P GS + +CP G D++EC P C
Sbjct: 669 CQDVDECTQSPGLCGRG-ACKNLP--GS--FRCVCPAGFRGSACEEDVDECAQEPPPCGP 723
Query: 211 GSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT 269
G C+N + C C G+ G C+D+DEC C G+C NT GSF CVCP G
Sbjct: 724 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGF 783
Query: 270 RHEPELQLCRDIDECEGETETHYIESDYERGDIP-PTFPTRTEL--------------AS 314
+ C D+DECE E G P+ L A
Sbjct: 784 QPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAP 843
Query: 315 PC-DNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
PC +G C NT G F C C GY R R G C A L
Sbjct: 844 PCGPHGHCTNTEGSFRCSCAPGY-------RAPSGRPGPC-----------ADVNECLEG 885
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGS 433
+ C G + G GA+C DVDEC+ +LC G C NTDGS
Sbjct: 886 DFCFPHGECLNTDGSFACTCAPGYRPG---PRGASCLDVDECS-EEDLCQSGICTNTDGS 941
Query: 434 YRCDCPPG 441
+ C CPPG
Sbjct: 942 FECICPPG 949
Score = 192 bits (469), Expect = 2e-48
Identities = 129/375 (34%), Positives = 164/375 (43%), Gaps = 65/375 (17%)
Query: 88 MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCEC 146
+C GRC++ + C C++G+R + C+DVDEC C GRC N+PGSFRC C
Sbjct: 555 VCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVC 614
Query: 147 LPGFTLSNDGRTCLGLKLGWGVS--CQACPAQGSE-LYAVLCPEGPSKDNGGA---DINE 200
PGF CL + V C + + + +CP G GA D++E
Sbjct: 615 GPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDE 674
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCAGGQCRNTAG 259
CT PG C G+C+NL +RC+C G+ A C D+DEC C G+C NTAG
Sbjct: 675 CTQSPGLCGRGACKNLPGSFRCVCPAGFRGSA---CEEDVDECAQEPPPCGPGRCDNTAG 731
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG 319
SF C CP G R C+D+DEC PP PC G
Sbjct: 732 SFHCACPAGFRSRGPGAPCQDVDECARS---------------PP----------PCTYG 766
Query: 320 RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCE--AAAPELLLRQECCC 377
RC NT G F+C C +G+ +A C D VD +CE A P QEC
Sbjct: 767 RCENTEGSFQCVCPMGFQPNAAGSECED----------VD-ECENHLACPG----QECVN 811
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG-GTCVNTDGSYRC 436
S G S +G C DVDEC+ A C G C NT+GS+RC
Sbjct: 812 SPG----SFQCRACPSGHHLHRG-------RCTDVDECSSGAPPCGPHGHCTNTEGSFRC 860
Query: 437 DCPPGLTLDSTGTAP 451
C PG S P
Sbjct: 861 SCAPGYRAPSGRPGP 875
Score = 174 bits (424), Expect = 5e-43
Identities = 125/377 (33%), Positives = 171/377 (45%), Gaps = 42/377 (11%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCL 64
+C +GIC N DG FECIC PG+ +G + A C DVDECR+ P +C RC N+ GSY C+
Sbjct: 929 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 988
Query: 65 --CEPGFAPTAAGYCADVDECA--ADSMCKGGRCVNSEGSFQC--VCEAGYRPTATRGAC 118
C+PG+ G C DVDEC +C RC N+ GS++C C+ GY+PT G C
Sbjct: 989 RDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PGGGC 1047
Query: 119 VDVDECEEQRVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSCQACP 174
DVDEC + C + C N PGSF+C C G+ + DGR C+ + + GV C A
Sbjct: 1048 QDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGV-CGAAL 1106
Query: 175 AQGSE-LYAVLCPEGPSKDN--GGADINECTAV---PGACPHGSCENLEPGY-------R 221
+ E + +CP P + + G + T+ PG+ P + P R
Sbjct: 1107 CENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGMFPGSQPQAPASPVLPARPPPPPLPR 1166
Query: 222 CICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI 281
P P G R+ C RN C C G E CR I
Sbjct: 1167 RPSTPRQGPVGSGR-RECYFDTAAPDACDNILARNVTWQ-ECCCTVG---EGWGSGCR-I 1220
Query: 282 DECEG-ETETHYIESDYERGDIPPT--FPTRTEL-------ASPCDNGRCINTHGGFECE 331
+C G ET + + RG + P+ R ++ C +G C+NT G+ C
Sbjct: 1221 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1280
Query: 332 CELGYVLDATAQRCLDN 348
C GY C+DN
Sbjct: 1281 CSNGYYYHTQRLECIDN 1297
Score = 125 bits (301), Expect = 4e-28
Identities = 89/280 (31%), Positives = 107/280 (38%), Gaps = 43/280 (15%)
Query: 188 GPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQ 246
GP G C P C G C + GY C CD G+ G C D+DEC
Sbjct: 536 GPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVP 595
Query: 247 SYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTF 306
CA G+C N+ GSF CVC G R P C D+DEC +PP
Sbjct: 596 PPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECH---------------RVPP-- 638
Query: 307 PTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD-----NRRGSCWR---RVV 358
PCD GRC NT G F C C GY C D G C R + +
Sbjct: 639 --------PCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNL 690
Query: 359 DGQCEAAAPELLLRQEC------CCSVGLAWGSXXXXXXXXXXXXX--KGF-AKLDGATC 409
G P C C G GF ++ GA C
Sbjct: 691 PGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 750
Query: 410 RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+DVDECA S C G C NT+GS++C CP G ++ G+
Sbjct: 751 QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGS 790
Score = 113 bits (272), Expect = 1e-24
Identities = 85/279 (30%), Positives = 113/279 (40%), Gaps = 26/279 (9%)
Query: 3 NGGMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C + +C+N+ G F+C+C GYE +G C DV+EC VC C N GS+
Sbjct: 1055 NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSF 1114
Query: 62 --TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C P G C V + M G + + S P R +
Sbjct: 1115 LCVCPNSPEEFDPMTGRC--VPPRTSAGMFPGSQ-PQAPASPVLPARPPPPPLPRRPST- 1170
Query: 120 DVDECEEQRVCRNGR--CH-NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC--QACP 174
Q +GR C+ +T C+ + ++ C + GWG C Q CP
Sbjct: 1171 -----PRQGPVGSGRRECYFDTAAPDACDNILARNVTWQ-ECCCTVGEGWGSGCRIQQCP 1224
Query: 175 AQGSELYAVLCPEG-----PSKDNG-GADINECTAVPG-ACPHGSCENLEPGYRCICDPG 227
+ Y LCP G PS D D++EC C G C N PGY C C G
Sbjct: 1225 GTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNG 1284
Query: 228 YHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
Y+ L C D DEC + C GG+C NT GS+ C C
Sbjct: 1285 YYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1323
Score = 90.2 bits (214), Expect = 1e-17
Identities = 58/157 (36%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Query: 34 ALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADVDECA-ADSMCK 90
+L RDVDEC+ +VC+ G C NTA Y+C C G + T C D DECA + C+
Sbjct: 1249 SLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACE 1308
Query: 91 GGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN-GRCHNTPGSFRCECLPG 149
GGRCVN+ GS+ C CE ++ CV E Q + N G C G+ P
Sbjct: 1309 GGRCVNTVGSYHCTCEPPLVLDGSQRRCV---SNESQSLDDNLGVCWQEVGADLVCSHPR 1365
Query: 150 FTLSNDGRTCLGL-KLGWGVSCQACPAQGSELYAVLC 185
C L WG+ C CPAQ S+ + LC
Sbjct: 1366 LDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC 1402
Score = 86.6 bits (205), Expect = 2e-16
Identities = 47/120 (39%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Query: 49 CRRGRCRNT-AGSYTCLCEPG---FAPTA-AGYCADVDECAA--DSMCKGGRCVNSEGSF 101
CR +C T Y LC G AP+ DVDEC D +CK G CVN+ +
Sbjct: 1218 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 1277
Query: 102 QCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
C C GY R C+D DEC +E+ C GRC NT GS+ C C P L R C+
Sbjct: 1278 SCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 1337
Score = 82.2 bits (194), Expect = 3e-15
Identities = 47/117 (40%), Positives = 58/117 (49%), Gaps = 10/117 (8%)
Query: 53 RCRNTAGSYTCLCEPGFAPTAAGYCAD------VDECAADSMCKGGRCVNSEGSFQCVCE 106
R R+T S+ EP + AG A+ +EC C GRCV F C C
Sbjct: 1501 RSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCF 1560
Query: 107 AGYRPTATRGACVDVDECEEQR----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
GYR TR ACVD++EC+E +C N RC NT GSFRC C PGF ++ C
Sbjct: 1561 DGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 81.8 bits (193), Expect = 5e-15
Identities = 63/202 (31%), Positives = 79/202 (39%), Gaps = 43/202 (21%)
Query: 201 CTAVPG---ACPHGSCENLEPG-YRCICDPG---YHPDAD-GLCRDIDECDMHQSY-CAG 251
CT G C C E Y+ +C G P D L RD+DEC + + C
Sbjct: 1208 CTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKS 1267
Query: 252 GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
G C NTA ++C C G + + C D DEC E
Sbjct: 1268 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPA--------------------- 1306
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRC-------LDNRRGSCWRRV-VDGQC- 362
C+ GRC+NT G + C CE VLD + +RC LD+ G CW+ V D C
Sbjct: 1307 ----CEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCS 1362
Query: 363 EAAAPELLLRQECCCSVGLAWG 384
ECCC G AWG
Sbjct: 1363 HPRLDRQATYTECCCLYGEAWG 1384
Score = 81.0 bits (191), Expect = 8e-15
Identities = 44/145 (30%), Positives = 60/145 (41%), Gaps = 5/145 (3%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C GF G C DVDECA C+ G C N+ G + CVC G+ ++R +C+
Sbjct: 344 CPTGFE-RVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 402
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
E + G C C ++ C + WG CQ CP GSE + +
Sbjct: 403 SEAK----GPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREI 458
Query: 185 CPEGPSKDNGGADINECTAVPGACP 209
CP GP +D+ T G P
Sbjct: 459 CPAGPGYHYSASDLRYNTRPLGQEP 483
Score = 70.5 bits (165), Expect = 1e-11
Identities = 28/62 (45%), Positives = 34/62 (54%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G+C N G+ C C GY ++ C D DEC D C GRC NT GSY C C
Sbjct: 1264 VCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1323
Query: 66 EP 67
EP
Sbjct: 1324 EP 1325
Score = 69.7 bits (163), Expect = 2e-11
Identities = 38/108 (35%), Positives = 50/108 (46%), Gaps = 13/108 (12%)
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK----------- 399
G C+R + G+C + P L ++ CC GLAWG +
Sbjct: 287 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPT 346
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
GF +++G +C DVDECA C G C NT G Y C CP G LDS+
Sbjct: 347 GFERVNG-SCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSS 392
Score = 69.3 bits (162), Expect = 3e-11
Identities = 30/69 (43%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPR---VCRRGRCRNTAGSYTC 63
CTNG C + GF C C GY C D++EC + +C RC NT GS+ C
Sbjct: 1543 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1602
Query: 64 LCEPGFAPT 72
+C PGFAPT
Sbjct: 1603 ICRPGFAPT 1611
Score = 65.7 bits (153), Expect = 3e-10
Identities = 29/75 (38%), Positives = 41/75 (54%), Gaps = 6/75 (8%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNR-----RGSCWRRVVDGQCEAAAPELL 370
C +G C NT GG+ C C G++LD++ C+ +G C+R + DG C +
Sbjct: 367 CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNI 426
Query: 371 LRQECCCS-VGLAWG 384
+Q CCCS VG AWG
Sbjct: 427 TKQICCCSRVGKAWG 441
Score = 58.8 bits (136), Expect = 4e-08
Identities = 35/93 (37%), Positives = 43/93 (46%), Gaps = 10/93 (10%)
Query: 147 LPGFTLSNDGRTCLGLKLGWGV-SCQACPAQGSELYAVLCPEGP-----SKDNGGA-DIN 199
LPG L C G L WGV CQ C + V P+GP + NG D++
Sbjct: 302 LPG--LRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVD 359
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
EC A G C HG C N GY C+C G+ D+
Sbjct: 360 EC-ATGGRCQHGECANTRGGYTCVCPDGFLLDS 391
Score = 58.8 bits (136), Expect = 4e-08
Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 7/83 (8%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQS---YCAGG 252
+ EC + G C +G C + G+ C C GY D + C DI+ECD ++ C
Sbjct: 1533 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 253 QCRNTAGSFTCVCPEG--TRHEP 273
+C NT GSF C+C G H+P
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQP 1614
Score = 52.0 bits (119), Expect = 4e-06
Identities = 22/39 (56%), Positives = 23/39 (58%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
C D DECA C GG CVNT GSY C C P L LD +
Sbjct: 1294 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGS 1332
Score = 49.6 bits (113), Expect = 2e-05
Identities = 22/47 (46%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
C G+E + C DVDEC R C+ G C NT G YTC+C GF
Sbjct: 344 CPTGFERVNGS--CEDVDECATGGR-CQHGECANTRGGYTCVCPDGF 387
Score = 48.8 bits (111), Expect = 4e-05
Identities = 20/45 (44%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C G+ +G C D+DEC C G+C NT G +TCVCP+G
Sbjct: 344 CPTGFER-VNGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDG 386
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/113 (29%), Positives = 43/113 (38%), Gaps = 25/113 (22%)
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDY 297
+ +EC + C G+C FTC C +G R + C DI+EC+
Sbjct: 1533 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECD------------ 1579
Query: 298 ERGDIPPTFPTRTELASP-CDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
E ASP C N RC+NT G F C C G+ C R
Sbjct: 1580 -----------EAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1621
Score = 43.2 bits (97), Expect = 0.002
Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 3/36 (8%)
Query: 409 CRDVDEC---ALSAELCAGGTCVNTDGSYRCDCPPG 441
C D++EC ++ LC C+NTDGS+RC C PG
Sbjct: 1572 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1607
Score = 37.9 bits (84), Expect = 0.073
Identities = 12/22 (54%), Positives = 15/22 (68%)
Query: 6 MCTNGICKNIDGGFECICKPGY 27
+C N C N DG F CIC+PG+
Sbjct: 1587 LCVNARCLNTDGSFRCICRPGF 1608
Score = 37.1 bits (82), Expect = 0.13
Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 4/55 (7%)
Query: 4 GGMCTNGICKNIDGGFECICKPGY--ESGSEGALCRDVDECRDNP--RVCRRGRC 54
GG C +G C N GG+ C+C G+ +S + + V P RV R G C
Sbjct: 364 GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGC 418
Score = 37.1 bits (82), Expect = 0.13
Identities = 14/44 (31%), Positives = 20/44 (45%)
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL 162
++ +EC C NGRC P F C C G+ L C+ +
Sbjct: 1532 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDI 1575
Score = 31.1 bits (67), Expect = 8.4
Identities = 12/30 (40%), Positives = 14/30 (46%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDP 226
D +EC AC G C N Y C C+P
Sbjct: 1296 DNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
>AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth
factor-beta binding protein 4S protein.
Length = 1557
Score = 258 bits (633), Expect = 2e-68
Identities = 163/448 (36%), Positives = 201/448 (44%), Gaps = 62/448 (13%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G C+N G F C+C GY++ GA C+DVDEC +P +C RG C+N GS+ C+C
Sbjct: 573 CDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCP 632
Query: 67 PGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC- 124
GF +A DVDECA + C GRC N+ GSF C C AG+R C DVDEC
Sbjct: 633 AGFRGSACE--EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECA 690
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSC--QACPAQGSELY 181
C GRC NT GSF+C C GF + G C + + ++C Q C
Sbjct: 691 RSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQ 750
Query: 182 AVLCPEGPSKDNGG-ADINECTA-VPGACPHGSCENLEPGYRCICDPGYHPDA--DGLCR 237
CP G G D++EC++ P PHG C N E +RC C PGY + G C
Sbjct: 751 CRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCA 810
Query: 238 DIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
D++EC + +C G+C NT GSF C C G R P C D+DEC E
Sbjct: 811 DVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEE--------- 860
Query: 297 YERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRR 356
D+ C +G C NT G FEC C G+ CLD
Sbjct: 861 ----DL-------------CQSGICTNTDGSFECICPPGHRAGPDLASCLD--------- 894
Query: 357 VVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDEC- 415
VD +C P L Q C S G G+ TC DVDEC
Sbjct: 895 -VD-ECRERGPALCGSQRCENSPG---------SYRCVRDCDPGYHAGPEGTCDDVDECQ 943
Query: 416 ALSAELCAGGTCVNTDGSYRCD--CPPG 441
E+C C NT GSYRC C PG
Sbjct: 944 EYGPEICGAQRCENTPGSYRCTPACDPG 971
Score = 252 bits (616), Expect = 3e-66
Identities = 167/480 (34%), Positives = 203/480 (42%), Gaps = 62/480 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C + G+ C C G+ +G C DVDECR P C GRC N+ GS+
Sbjct: 485 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 544
Query: 63 CLCEPGF-APTAAGYCADVDEC-AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C+C PGF A A C DVDEC C GRC N+ GSF CVC AGY+ +C D
Sbjct: 545 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 604
Query: 121 VDEC-EEQRVCRNGRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQ 176
VDEC + +C G C N PGSFRC C GF D C G C
Sbjct: 605 VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPG--RCDNT 662
Query: 177 GSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ CP G GA D++EC P C +G CEN E ++C+C G+ P+A
Sbjct: 663 AGSFHCA-CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAA 721
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTC-VCPEGTRHEPELQLCRDIDECEGET--- 288
G C D+DEC+ H + C G +C N+ GSF C CP G H C D+DEC
Sbjct: 722 GSECEDVDECENHLA-CPGQECVNSPGSFQCRACPSG--HHLHRGRCTDVDECSSGAPPC 778
Query: 289 --ETHYIESDYE-RGDIPPTFPTRTELASPC-------------DNGRCINTHGGFECEC 332
H ++ R P + + PC +G C+NT G F C C
Sbjct: 779 GPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC 838
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
GY CLD S G C EC C G G
Sbjct: 839 APGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSF----ECICPPGHRAGP------- 887
Query: 393 XXXXXXKGFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC--DCPPGLTLDSTGT 449
D A+C DVDEC LC C N+ GSYRC DC PG GT
Sbjct: 888 ------------DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT 935
Score = 231 bits (564), Expect = 5e-60
Identities = 169/486 (34%), Positives = 215/486 (44%), Gaps = 56/486 (11%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCLC 65
C C N G F+C P G C DVDEC C G C NT GS+ C C
Sbjct: 737 CPGQECVNSPGSFQCRACPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSC 795
Query: 66 EPGF-APTAA-GYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
PG+ AP+ G CADV+EC C G C+N++GSF C C GYRP +C+DVD
Sbjct: 796 APGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVD 855
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL--------GLKLGWGVSCQACP 174
EC E+ +C++G C NT GSF C C PG D +CL G L C+ P
Sbjct: 856 ECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP 915
Query: 175 AQGSELYAVLCPEGPSKDNGGA--DINECTAV-PGACPHGSCENLEPGYRC--ICDPGYH 229
GS C G G D++EC P C CEN YRC CDPGY
Sbjct: 916 --GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ 973
Query: 230 PDADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG-E 287
P G C+D+DEC ++S+C A C+N GSF C+C +G + + C D++ECE +
Sbjct: 974 PTPGGGCQDVDEC-RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQ 1032
Query: 288 TETHYIESDYERGDIPPTFPTRTELASPCDNGRCI--NTHGGF----ECECELGYVLDAT 341
+ G P E P GRC+ T G + + VL A
Sbjct: 1033 GVCGAALCENVEGSFLCVCPNSPEEFDPM-TGRCVPPRTSAGMFPGSQPQAPASPVLPAR 1091
Query: 342 AQRCLDNRRGSCWRRVVDG----QC--EAAAPE----LLLR----QECCCSVGLAWGS-- 385
RR S R+ G +C + AAP+ +L R QECCC+VG WGS
Sbjct: 1092 PPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGC 1151
Query: 386 -------XXXXXXXXXXXXXKGFAKLDG--ATCRDVDECAL-SAELCAGGTCVNTDGSYR 435
+G+ G + RDVDEC L ++C G CVNT Y
Sbjct: 1152 RIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYS 1211
Query: 436 CDCPPG 441
C C G
Sbjct: 1212 CYCSNG 1217
Score = 229 bits (559), Expect = 2e-59
Identities = 149/428 (34%), Positives = 183/428 (42%), Gaps = 55/428 (12%)
Query: 42 CRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAG-YCADVDEC-AADSMCKGGRCVNSEG 99
C+ NP+VC GRC + YTC C+ GF + G C DVDEC C GRC NS G
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
Query: 100 SFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
SF+CVC G+R C+DVDEC C GRC NTPGSF C C G+ + G +
Sbjct: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 601
Query: 159 CLGLK--------LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH 210
C + G G +C+ P GS + +CP G D++EC P C
Sbjct: 602 CQDVDECTQSPGLCGRG-ACKNLP--GS--FRCVCPAGFRGSACEEDVDECAQEPPPCGP 656
Query: 211 GSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT 269
G C+N + C C G+ G C+D+DEC C G+C NT GSF CVCP G
Sbjct: 657 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGF 716
Query: 270 RHEPELQLCRDIDECEGETETHYIESDYERGDIP-PTFPTRTEL--------------AS 314
+ C D+DECE E G P+ L A
Sbjct: 717 QPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAP 776
Query: 315 PC-DNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
PC +G C NT G F C C GY R R G C A L
Sbjct: 777 PCGPHGHCTNTEGSFRCSCAPGY-------RAPSGRPGPC-----------ADVNECLEG 818
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGS 433
+ C G + G GA+C DVDEC+ +LC G C NTDGS
Sbjct: 819 DFCFPHGECLNTDGSFACTCAPGYRPG---PRGASCLDVDECS-EEDLCQSGICTNTDGS 874
Query: 434 YRCDCPPG 441
+ C CPPG
Sbjct: 875 FECICPPG 882
Score = 192 bits (469), Expect = 2e-48
Identities = 129/375 (34%), Positives = 164/375 (43%), Gaps = 65/375 (17%)
Query: 88 MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPGSFRCEC 146
+C GRC++ + C C++G+R + C+DVDEC C GRC N+PGSFRC C
Sbjct: 488 VCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVC 547
Query: 147 LPGFTLSNDGRTCLGLKLGWGVS--CQACPAQGSE-LYAVLCPEGPSKDNGGA---DINE 200
PGF CL + V C + + + +CP G GA D++E
Sbjct: 548 GPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDE 607
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCAGGQCRNTAG 259
CT PG C G+C+NL +RC+C G+ A C D+DEC C G+C NTAG
Sbjct: 608 CTQSPGLCGRGACKNLPGSFRCVCPAGFRGSA---CEEDVDECAQEPPPCGPGRCDNTAG 664
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG 319
SF C CP G R C+D+DEC PP PC G
Sbjct: 665 SFHCACPAGFRSRGPGAPCQDVDECARS---------------PP----------PCTYG 699
Query: 320 RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCE--AAAPELLLRQECCC 377
RC NT G F+C C +G+ +A C D VD +CE A P QEC
Sbjct: 700 RCENTEGSFQCVCPMGFQPNAAGSECED----------VD-ECENHLACPG----QECVN 744
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG-GTCVNTDGSYRC 436
S G S +G C DVDEC+ A C G C NT+GS+RC
Sbjct: 745 SPG----SFQCRACPSGHHLHRG-------RCTDVDECSSGAPPCGPHGHCTNTEGSFRC 793
Query: 437 DCPPGLTLDSTGTAP 451
C PG S P
Sbjct: 794 SCAPGYRAPSGRPGP 808
Score = 174 bits (424), Expect = 5e-43
Identities = 125/377 (33%), Positives = 171/377 (45%), Gaps = 42/377 (11%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCL 64
+C +GIC N DG FECIC PG+ +G + A C DVDECR+ P +C RC N+ GSY C+
Sbjct: 862 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 921
Query: 65 --CEPGFAPTAAGYCADVDECA--ADSMCKGGRCVNSEGSFQC--VCEAGYRPTATRGAC 118
C+PG+ G C DVDEC +C RC N+ GS++C C+ GY+PT G C
Sbjct: 922 RDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PGGGC 980
Query: 119 VDVDECEEQRVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSCQACP 174
DVDEC + C + C N PGSF+C C G+ + DGR C+ + + GV C A
Sbjct: 981 QDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGV-CGAAL 1039
Query: 175 AQGSE-LYAVLCPEGPSKDN--GGADINECTAV---PGACPHGSCENLEPGY-------R 221
+ E + +CP P + + G + T+ PG+ P + P R
Sbjct: 1040 CENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGMFPGSQPQAPASPVLPARPPPPPLPR 1099
Query: 222 CICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI 281
P P G R+ C RN C C G E CR I
Sbjct: 1100 RPSTPRQGPVGSGR-RECYFDTAAPDACDNILARNVTWQ-ECCCTVG---EGWGSGCR-I 1153
Query: 282 DECEG-ETETHYIESDYERGDIPPT--FPTRTEL-------ASPCDNGRCINTHGGFECE 331
+C G ET + + RG + P+ R ++ C +G C+NT G+ C
Sbjct: 1154 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1213
Query: 332 CELGYVLDATAQRCLDN 348
C GY C+DN
Sbjct: 1214 CSNGYYYHTQRLECIDN 1230
Score = 125 bits (301), Expect = 4e-28
Identities = 89/280 (31%), Positives = 107/280 (38%), Gaps = 43/280 (15%)
Query: 188 GPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQ 246
GP G C P C G C + GY C CD G+ G C D+DEC
Sbjct: 469 GPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVP 528
Query: 247 SYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTF 306
CA G+C N+ GSF CVC G R P C D+DEC +PP
Sbjct: 529 PPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECH---------------RVPP-- 571
Query: 307 PTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD-----NRRGSCWR---RVV 358
PCD GRC NT G F C C GY C D G C R + +
Sbjct: 572 --------PCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNL 623
Query: 359 DGQCEAAAPELLLRQEC------CCSVGLAWGSXXXXXXXXXXXXX--KGF-AKLDGATC 409
G P C C G GF ++ GA C
Sbjct: 624 PGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 683
Query: 410 RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+DVDECA S C G C NT+GS++C CP G ++ G+
Sbjct: 684 QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGS 723
Score = 113 bits (272), Expect = 1e-24
Identities = 85/279 (30%), Positives = 113/279 (40%), Gaps = 26/279 (9%)
Query: 3 NGGMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C + +C+N+ G F+C+C GYE +G C DV+EC VC C N GS+
Sbjct: 988 NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSF 1047
Query: 62 --TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C P G C V + M G + + S P R +
Sbjct: 1048 LCVCPNSPEEFDPMTGRC--VPPRTSAGMFPGSQ-PQAPASPVLPARPPPPPLPRRPST- 1103
Query: 120 DVDECEEQRVCRNGR--CH-NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC--QACP 174
Q +GR C+ +T C+ + ++ C + GWG C Q CP
Sbjct: 1104 -----PRQGPVGSGRRECYFDTAAPDACDNILARNVTWQ-ECCCTVGEGWGSGCRIQQCP 1157
Query: 175 AQGSELYAVLCPEG-----PSKDNG-GADINECTAVPG-ACPHGSCENLEPGYRCICDPG 227
+ Y LCP G PS D D++EC C G C N PGY C C G
Sbjct: 1158 GTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNG 1217
Query: 228 YHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
Y+ L C D DEC + C GG+C NT GS+ C C
Sbjct: 1218 YYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1256
Score = 90.2 bits (214), Expect = 1e-17
Identities = 58/157 (36%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Query: 34 ALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADVDECA-ADSMCK 90
+L RDVDEC+ +VC+ G C NTA Y+C C G + T C D DECA + C+
Sbjct: 1182 SLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACE 1241
Query: 91 GGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN-GRCHNTPGSFRCECLPG 149
GGRCVN+ GS+ C CE ++ CV E Q + N G C G+ P
Sbjct: 1242 GGRCVNTVGSYHCTCEPPLVLDGSQRRCV---SNESQSLDDNLGVCWQEVGADLVCSHPR 1298
Query: 150 FTLSNDGRTCLGL-KLGWGVSCQACPAQGSELYAVLC 185
C L WG+ C CPAQ S+ + LC
Sbjct: 1299 LDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC 1335
Score = 86.6 bits (205), Expect = 2e-16
Identities = 47/120 (39%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Query: 49 CRRGRCRNT-AGSYTCLCEPG---FAPTA-AGYCADVDECAA--DSMCKGGRCVNSEGSF 101
CR +C T Y LC G AP+ DVDEC D +CK G CVN+ +
Sbjct: 1151 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 1210
Query: 102 QCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
C C GY R C+D DEC +E+ C GRC NT GS+ C C P L R C+
Sbjct: 1211 SCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 1270
Score = 82.2 bits (194), Expect = 3e-15
Identities = 47/117 (40%), Positives = 58/117 (49%), Gaps = 10/117 (8%)
Query: 53 RCRNTAGSYTCLCEPGFAPTAAGYCAD------VDECAADSMCKGGRCVNSEGSFQCVCE 106
R R+T S+ EP + AG A+ +EC C GRCV F C C
Sbjct: 1434 RSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCF 1493
Query: 107 AGYRPTATRGACVDVDECEEQR----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
GYR TR ACVD++EC+E +C N RC NT GSFRC C PGF ++ C
Sbjct: 1494 DGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 81.8 bits (193), Expect = 5e-15
Identities = 63/202 (31%), Positives = 79/202 (39%), Gaps = 43/202 (21%)
Query: 201 CTAVPG---ACPHGSCENLEPG-YRCICDPG---YHPDAD-GLCRDIDECDMHQSY-CAG 251
CT G C C E Y+ +C G P D L RD+DEC + + C
Sbjct: 1141 CTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKS 1200
Query: 252 GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
G C NTA ++C C G + + C D DEC E
Sbjct: 1201 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPA--------------------- 1239
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRC-------LDNRRGSCWRRV-VDGQC- 362
C+ GRC+NT G + C CE VLD + +RC LD+ G CW+ V D C
Sbjct: 1240 ----CEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCS 1295
Query: 363 EAAAPELLLRQECCCSVGLAWG 384
ECCC G AWG
Sbjct: 1296 HPRLDRQATYTECCCLYGEAWG 1317
Score = 81.0 bits (191), Expect = 8e-15
Identities = 44/145 (30%), Positives = 60/145 (41%), Gaps = 5/145 (3%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C GF G C DVDECA C+ G C N+ G + CVC G+ ++R +C+
Sbjct: 277 CPTGFE-RVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 335
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
E + G C C ++ C + WG CQ CP GSE + +
Sbjct: 336 SEAK----GPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREI 391
Query: 185 CPEGPSKDNGGADINECTAVPGACP 209
CP GP +D+ T G P
Sbjct: 392 CPAGPGYHYSASDLRYNTRPLGQEP 416
Score = 70.5 bits (165), Expect = 1e-11
Identities = 28/62 (45%), Positives = 34/62 (54%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G+C N G+ C C GY ++ C D DEC D C GRC NT GSY C C
Sbjct: 1197 VCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1256
Query: 66 EP 67
EP
Sbjct: 1257 EP 1258
Score = 69.7 bits (163), Expect = 2e-11
Identities = 38/108 (35%), Positives = 50/108 (46%), Gaps = 13/108 (12%)
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK----------- 399
G C+R + G+C + P L ++ CC GLAWG +
Sbjct: 220 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPT 279
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
GF +++G +C DVDECA C G C NT G Y C CP G LDS+
Sbjct: 280 GFERVNG-SCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSS 325
Score = 69.3 bits (162), Expect = 3e-11
Identities = 30/69 (43%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPR---VCRRGRCRNTAGSYTC 63
CTNG C + GF C C GY C D++EC + +C RC NT GS+ C
Sbjct: 1476 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1535
Query: 64 LCEPGFAPT 72
+C PGFAPT
Sbjct: 1536 ICRPGFAPT 1544
Score = 65.7 bits (153), Expect = 3e-10
Identities = 29/75 (38%), Positives = 41/75 (54%), Gaps = 6/75 (8%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNR-----RGSCWRRVVDGQCEAAAPELL 370
C +G C NT GG+ C C G++LD++ C+ +G C+R + DG C +
Sbjct: 300 CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNI 359
Query: 371 LRQECCCS-VGLAWG 384
+Q CCCS VG AWG
Sbjct: 360 TKQICCCSRVGKAWG 374
Score = 58.8 bits (136), Expect = 4e-08
Identities = 35/93 (37%), Positives = 43/93 (46%), Gaps = 10/93 (10%)
Query: 147 LPGFTLSNDGRTCLGLKLGWGV-SCQACPAQGSELYAVLCPEGP-----SKDNGGA-DIN 199
LPG L C G L WGV CQ C + V P+GP + NG D++
Sbjct: 235 LPG--LRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVD 292
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
EC A G C HG C N GY C+C G+ D+
Sbjct: 293 EC-ATGGRCQHGECANTRGGYTCVCPDGFLLDS 324
Score = 58.8 bits (136), Expect = 4e-08
Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 7/83 (8%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQS---YCAGG 252
+ EC + G C +G C + G+ C C GY D + C DI+ECD ++ C
Sbjct: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 253 QCRNTAGSFTCVCPEG--TRHEP 273
+C NT GSF C+C G H+P
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQP 1547
Score = 52.0 bits (119), Expect = 4e-06
Identities = 22/39 (56%), Positives = 23/39 (58%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
C D DECA C GG CVNT GSY C C P L LD +
Sbjct: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGS 1265
Score = 49.6 bits (113), Expect = 2e-05
Identities = 22/47 (46%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
C G+E + C DVDEC R C+ G C NT G YTC+C GF
Sbjct: 277 CPTGFERVNGS--CEDVDECATGGR-CQHGECANTRGGYTCVCPDGF 320
Score = 48.8 bits (111), Expect = 4e-05
Identities = 20/45 (44%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C G+ +G C D+DEC C G+C NT G +TCVCP+G
Sbjct: 277 CPTGFER-VNGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDG 319
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/113 (29%), Positives = 43/113 (38%), Gaps = 25/113 (22%)
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDY 297
+ +EC + C G+C FTC C +G R + C DI+EC+
Sbjct: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECD------------ 1512
Query: 298 ERGDIPPTFPTRTELASP-CDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
E ASP C N RC+NT G F C C G+ C R
Sbjct: 1513 -----------EAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
Score = 43.2 bits (97), Expect = 0.002
Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 3/36 (8%)
Query: 409 CRDVDEC---ALSAELCAGGTCVNTDGSYRCDCPPG 441
C D++EC ++ LC C+NTDGS+RC C PG
Sbjct: 1505 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1540
Score = 37.9 bits (84), Expect = 0.073
Identities = 12/22 (54%), Positives = 15/22 (68%)
Query: 6 MCTNGICKNIDGGFECICKPGY 27
+C N C N DG F CIC+PG+
Sbjct: 1520 LCVNARCLNTDGSFRCICRPGF 1541
Score = 37.1 bits (82), Expect = 0.13
Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 4/55 (7%)
Query: 4 GGMCTNGICKNIDGGFECICKPGY--ESGSEGALCRDVDECRDNP--RVCRRGRC 54
GG C +G C N GG+ C+C G+ +S + + V P RV R G C
Sbjct: 297 GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGC 351
Score = 37.1 bits (82), Expect = 0.13
Identities = 14/44 (31%), Positives = 20/44 (45%)
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL 162
++ +EC C NGRC P F C C G+ L C+ +
Sbjct: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDI 1508
Score = 31.1 bits (67), Expect = 8.4
Identities = 12/30 (40%), Positives = 14/30 (46%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDP 226
D +EC AC G C N Y C C+P
Sbjct: 1229 DNDECADEEPACEGGRCVNTVGSYHCTCEP 1258
>AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant
protein.
Length = 830
Score = 257 bits (629), Expect = 7e-68
Identities = 164/472 (34%), Positives = 217/472 (45%), Gaps = 40/472 (8%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C NG+C N+ G F C C G+ + +C D+DEC++ P R C NTAGSY C
Sbjct: 210 GVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCD 269
Query: 65 CEPGFAPTAAGYCADVDEC-AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C+PG+ T+ G C D +EC ++C G+C+++ GSF C+C G++ + C+D++E
Sbjct: 270 CKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINE 329
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSC---QACPAQG 177
CE C NG C NT GSF C C GF LS++ C+ + G G C Q G
Sbjct: 330 CERD-ACGNGTCRNTIGSFNCRCNHGFILSHN-NDCIDVDECASGNGNLCRNGQCINTVG 387
Query: 178 SELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
S + C EG G DINEC P C G+C+NL+ YRCIC PGY +
Sbjct: 388 S--FQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE- 444
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI--DECEGETETHY 292
C DIDEC CA G C NT GSF C+CPEG + C+D+ C + E
Sbjct: 445 KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGK 504
Query: 293 IESDYERGDIPPTFPTRTE---LASPCDNGRC-INTHGGFECECELGYVL----DATA-- 342
S R + PC+ C F C G + D +A
Sbjct: 505 CSSPKSRNHSKQECCCALKGEGWGDPCE--LCPTEPDEAFRQICPYGSGIIVGPDDSAVD 562
Query: 343 -QRCLDN---RRGSCWRRVVDGQCEAAAPELLLRQECC----CSVGLAWGSXX--XXXXX 392
C + + G C +CE +L EC CSVG G+
Sbjct: 563 MDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGG 622
Query: 393 XXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+GF TC D++ECA + LCA CVNT GSY C CP G L
Sbjct: 623 FECTCEEGFEPGPMMTCEDINECAQNPLLCA-FRCVNTYGSYECKCPVGYVL 673
Score = 246 bits (601), Expect = 2e-64
Identities = 147/437 (33%), Positives = 210/437 (48%), Gaps = 45/437 (10%)
Query: 24 KPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADVDE 82
+PG+ L D+DECR+ P VC G C N GS+ C C G F C D+DE
Sbjct: 187 RPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDE 246
Query: 83 CAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHNTPG 140
C +C + C+N+ GS++C C+ GYR T+T G C D +EC+E +C +G+C +T G
Sbjct: 247 CQNGPVCQRNAECINTAGSYRCDCKPGYRFTST-GQCNDRNECQEIPNICSHGQCIDTVG 305
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYAVLCPEG--PSKDNGGAD 197
SF C C GF ++D CL + +C + + + C G S +N D
Sbjct: 306 SFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCID 365
Query: 198 INECTAVPG-ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCR 255
++EC + G C +G C N ++C C+ GY DG C DI+EC + CA G C+
Sbjct: 366 VDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQ 425
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N GS+ C+CP G + + + C DIDEC E E
Sbjct: 426 NLDGSYRCICPPG--YSLQNEKCEDIDECVEEPEI------------------------- 458
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C NT G F+C C G+ L ++ +RC D R C+ + G+C + +QEC
Sbjct: 459 CALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQEC 518
Query: 376 CCSV-GLAWGSXXXXXXXXXXXXXK-----GFAKLDGA--TCRDVDECALSAELCAGGTC 427
CC++ G WG + G + G + D+DEC ++C G C
Sbjct: 519 CCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK-EPDVCKHGQC 577
Query: 428 VNTDGSYRCDCPPGLTL 444
+NTDGSYRC+CP G L
Sbjct: 578 INTDGSYRCECPFGYIL 594
Score = 213 bits (521), Expect = 8e-55
Identities = 154/463 (33%), Positives = 207/463 (44%), Gaps = 65/463 (14%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCLC 65
C NG C+N G F C C G+ S C DVDEC N +CR G+C NT GS+ C C
Sbjct: 335 CGNGTCRNTIGSFNCRCNHGFIL-SHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQC 393
Query: 66 EPGFAPTAAGY-CADVDECAADSM-CKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
G+ G C D++EC + C G C N +GS++C+C GY + C D+DE
Sbjct: 394 NEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGY--SLQNEKCEDIDE 451
Query: 124 C-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
C EE +C G C NT GSF+C C GF+LS+ GR C L++ + C A +G +
Sbjct: 452 CVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSY---CYA-KFEGGK--- 504
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCE--NLEP--GYRCICD--PGYHPDADGLC 236
C S+++ + C A+ G CE EP +R IC G D
Sbjct: 505 --CSSPKSRNHSKQEC--CCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSA 560
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE------GETET 290
D+DEC C GQC NT GS+ C CP G + C D DEC T
Sbjct: 561 VDMDECK-EPDVCKHGQCINTDGSYRCECPFG--YILAGNECVDTDECSVGNPCGNGTCK 617
Query: 291 HYI---ESDYERGDIPPTFPTRTELASPCDNG-----RCINTHGGFECECELGYVLDATA 342
+ I E E G P T ++ N RC+NT+G +EC+C +GYVL
Sbjct: 618 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDR 677
Query: 343 QRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-ECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
+ C D + +CE + +Q EC +G G+
Sbjct: 678 RMCKD-----------EDECEEGKHDCTEKQMECKNLIG-----------TYMCICGPGY 715
Query: 402 AKL-DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+ DG C D +EC +C G C+NT GSY C+C G T
Sbjct: 716 QRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFT 758
Score = 202 bits (493), Expect = 2e-51
Identities = 105/288 (36%), Positives = 140/288 (48%), Gaps = 21/288 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NG +C NG C N G F+C C GYE +G C D++EC PR C G C+N GSY
Sbjct: 373 NGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYR 432
Query: 63 CLCEPGFAPTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C+C PG++ C D+DEC + +C G C N+EGSF+C+C G+ +++ C D+
Sbjct: 433 CICPPGYS-LQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDL 491
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK-LGWGVSCQACPAQGSEL 180
R C+ +C P + C LK GWG C+ CP + E
Sbjct: 492 ---------RMSYCYAKFEGGKCSS-PKSRNHSKQECCCALKGEGWGDPCELCPTEPDEA 541
Query: 181 YAVLCPEGP----SKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ +CP G D+ D++EC P C HG C N + YRC C GY A C
Sbjct: 542 FRQICPYGSGIIVGPDDSAVDMDECKE-PDVCKHGQCINTDGSYRCECPFGYIL-AGNEC 599
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
D DEC + C G C+N G F C C EG P + C DI+EC
Sbjct: 600 VDTDECSVGNP-CGNGTCKNVIGGFECTCEEGFEPGP-MMTCEDINEC 645
Score = 190 bits (463), Expect = 9e-48
Identities = 131/450 (29%), Positives = 189/450 (42%), Gaps = 64/450 (14%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADVDECA 84
G+ + D+DEC++ P +C+ G+C NT GS+ C C G + C DV+EC
Sbjct: 29 GFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECE 88
Query: 85 ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC-RNGRCHNTPGSFR 143
+C G C N+ G++ C+C Y C+D+ + +C RN N
Sbjct: 89 TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM----RRSLCYRNYYADNQ----T 140
Query: 144 CECLPGFTLSNDGRTCLGLKLG--WGVSCQACPAQGSELYAVLC-PEGPS-----KDNGG 195
C+ F ++ C +G W C+ CP ++ +A LC + P
Sbjct: 141 CDGELLFNMTKK-MCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP 199
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPG-YHPDADGLCRDIDECDMHQSYCAGGQC 254
DI+EC +PG C +G C N+ +RC C G ++ D +C DIDEC +C
Sbjct: 200 VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC 259
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NTAGS+ C C G R Q C D +EC+ E+ +
Sbjct: 260 INTAGSYRCDCKPGYRFTSTGQ-CNDRNECQ-------------------------EIPN 293
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNR--------RGSCWRRVVDGQCEAAA 366
C +G+CI+T G F C C G+ + CLD G+C + C
Sbjct: 294 ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNH 353
Query: 367 PELLLRQECC-----CSVG----LAWGSXXXXXXXXXXXXXKGF-AKLDGATCRDVDECA 416
+L C C+ G G +G+ DG TC D++EC
Sbjct: 354 GFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECL 413
Query: 417 LSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
L CA GTC N DGSYRC CPPG +L +
Sbjct: 414 LEPRKCAPGTCQNLDGSYRCICPPGYSLQN 443
Score = 160 bits (388), Expect = 1e-38
Identities = 116/373 (31%), Positives = 165/373 (44%), Gaps = 55/373 (14%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C G C+N+DG + CIC PGY +E C D+DEC + P +C G C NT GS+ CLC
Sbjct: 419 CAPGTCQNLDGSYRCICPPGYSLQNEK--CEDIDECVEEPEICALGTCSNTEGSFKCLCP 476
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVN----SEGSFQCVCEAGYRPTATRGACVDV 121
GF+ +++G C D+ + +GG+C + + +C C A +G
Sbjct: 477 EGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC-------ALKGEGWG- 528
Query: 122 DECEEQRVCRNGRCHNTPG-SFR--CECLPGFTLSNDGRTCLGLKLGWGVSC---QACPA 175
D CE C P +FR C G + D + C Q
Sbjct: 529 DPCE--------LCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINT 580
Query: 176 QGSELYAVLCPEGPS-KDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
GS Y CP G N D +EC+ V C +G+C+N+ G+ C C+ G+ P
Sbjct: 581 DGS--YRCECPFGYILAGNECVDTDECS-VGNPCGNGTCKNVIGGFECTCEEGFEPGPMM 637
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
C DI+EC + CA +C NT GS+ C CP G + ++C+D DECE E + E
Sbjct: 638 TCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDECE-EGKHDCTE 695
Query: 295 SDYERGDI--------PPTFPTRTE----------LASP--CDNGRCINTHGGFECECEL 334
E ++ P + R + P C+NGRC+NT G + CEC
Sbjct: 696 KQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECND 755
Query: 335 GYVLDATAQRCLD 347
G+ CLD
Sbjct: 756 GFTASPNQDECLD 768
Score = 149 bits (361), Expect = 2e-35
Identities = 131/477 (27%), Positives = 190/477 (39%), Gaps = 74/477 (15%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
G+C G C N G F+C C GY + +C DV+EC + P +C G C NT G+YTC+
Sbjct: 50 GLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC-ETPGICGPGTCYNTVGNYTCI 108
Query: 65 CEPGFAPTAAG-YCADVDE--C----AADSMCKGGRCVNSEGSFQCVC--EAGYRPTATR 115
C P + G C D+ C AD+ G + + C C G
Sbjct: 109 CPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPC 168
Query: 116 GACVDVDECEEQRVCRNGR-------CHNTPGSF-RCECLPGFTLSNDGRTCLGLKLGWG 167
C E +C + R P C +PG + C+ + +
Sbjct: 169 EQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVC---ENGVCINMVGSFR 225
Query: 168 VSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPG 227
C +L ++C + NG + A + C+ +PGYR
Sbjct: 226 CECPVGFFYNDKL--LVCEDIDECQNGPVCQRNAECINTAGSY-RCD-CKPGYRF----- 276
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE 287
+ G C D +EC + C+ GQC +T GSF C+C G + + +C DI+ECE +
Sbjct: 277 ---TSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERD 333
Query: 288 -----TETHYIESDYER----------GDIPPTFPTRTELASPCDNGRCINTHGGFECEC 332
T + I S R D + + C NG+CINT G F+C+C
Sbjct: 334 ACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQC 393
Query: 333 ELGYVLDATAQRCLD-NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
GY + + C+D N R+ G C+ L C C G +
Sbjct: 394 NEGYEVAPDGRTCVDINECLLEPRKCAPGTCQ----NLDGSYRCICPPGYS--------- 440
Query: 392 XXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
L C D+DEC E+CA GTC NT+GS++C CP G +L S+G
Sbjct: 441 ------------LQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSG 485
Score = 141 bits (342), Expect = 4e-33
Identities = 103/319 (32%), Positives = 131/319 (41%), Gaps = 50/319 (15%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDV--DEC--RDNPRVCRRGRCRNTAGSY 61
+C G C N +G F+C+C G+ S G C+D+ C + C + RN +
Sbjct: 458 ICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQE 517
Query: 62 TC-------------LC--EPGFA-----PTAAGY-------CADVDECAADSMCKGGRC 94
C LC EP A P +G D+DEC +CK G+C
Sbjct: 518 CCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQC 577
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT--- 151
+N++GS++C C GY CVD DEC C NG C N G F C C GF
Sbjct: 578 INTDGSYRCECPFGY--ILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGP 635
Query: 152 --LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGP--SKDNGGA-DINECTAVPG 206
D C L C GS Y CP G +D D +EC
Sbjct: 636 MMTCEDINECAQNPLLCAFRC--VNTYGS--YECKCPVGYVLREDRRMCKDEDECEEGKH 691
Query: 207 ACPHGS--CENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFT 262
C C+NL Y CIC PGY PD +G C D +EC C G+C NT GS+T
Sbjct: 692 DCTEKQMECKNLIGTYMCICGPGYQRRPDGEG-CVDENECQTKPGICENGRCLNTRGSYT 750
Query: 263 CVCPEGTRHEPELQLCRDI 281
C C +G P C D+
Sbjct: 751 CECNDGFTASPNQDECLDV 769
Score = 141 bits (342), Expect = 4e-33
Identities = 73/177 (41%), Positives = 93/177 (52%), Gaps = 7/177 (3%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C NG CKN+ GGFEC C+ G+E G C D++EC NP +C RC NT GSY C
Sbjct: 608 GNPCGNGTCKNVIGGFECTCEEGFEPGPM-MTCEDINECAQNPLLCAF-RCVNTYGSYEC 665
Query: 64 LCEPGFAPTA-AGYCADVDECAA---DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C G+ C D DEC D K C N G++ C+C GY+ CV
Sbjct: 666 KCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCV 725
Query: 120 DVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPA 175
D +EC+ + +C NGRC NT GS+ CEC GFT S + CL + L + A P+
Sbjct: 726 DENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDVILSLLLLSPAFPS 782
Score = 91.1 bits (216), Expect = 7e-18
Identities = 41/107 (38%), Positives = 58/107 (54%), Gaps = 7/107 (6%)
Query: 166 WGVSCQACPAQGSELYAVLCPEGPS-KDNGGA----DINECTAVPGACPHGSCENLEPGY 220
WG C+ CPA + Y +LCP G + N DI+EC +PG C G C N +
Sbjct: 5 WGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSF 64
Query: 221 RCICDPGYHPDAD-GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCP 266
+C C GY+ + D +C D++EC+ C G C NT G++TC+CP
Sbjct: 65 QCRCPTGYYLNEDTRVCDDVNECET-PGICGPGTCYNTVGNYTCICP 110
Score = 71.3 bits (167), Expect = 6e-12
Identities = 68/238 (28%), Positives = 93/238 (39%), Gaps = 42/238 (17%)
Query: 220 YRCICD--PGYHPDA-DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQ 276
Y+ +C G+ P+ + DIDEC C GG+C NT GSF C CP G + +
Sbjct: 20 YKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTR 79
Query: 277 LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGY 336
+C D++EC ET I G T T + P + +GG C
Sbjct: 80 VCDDVNEC----ETPGICGP---GTCYNTVGNYTCICPP----DYMQVNGGNNC------ 122
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQ-CEAAAPELLLRQECCCS--VGLAWGS-------- 385
+D C N D Q C+ + ++ CCCS +G AW
Sbjct: 123 -MDMRRSLCYRN-------YYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIP 174
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDV--DECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF +D T V DEC +C G C+N GS+RC+CP G
Sbjct: 175 STDEFATLCGSQRPGFV-IDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVG 231
Score = 69.3 bits (162), Expect = 3e-11
Identities = 67/266 (25%), Positives = 96/266 (36%), Gaps = 39/266 (14%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGY-HPDADGLCRDIDECDMHQSYCAGGQCR 255
D+NEC PG C G+C N Y CIC P Y + C D+ +++Y A Q
Sbjct: 83 DVNECET-PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 141
Query: 256 NTAGSFT-----CVCPE--GTRHEPELQLCR--DIDECE---GETETHYIESDYERGDIP 303
+ F C C G + C DE G ++ Y +P
Sbjct: 142 DGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYT--GLP 199
Query: 304 PTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCE 363
E+ C+NG CIN G F CEC +G+ + C D +D +C+
Sbjct: 200 VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCED----------ID-ECQ 248
Query: 364 AAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA 423
P EC + G G+ C D +EC +C+
Sbjct: 249 NG-PVCQRNAECINTAG-----------SYRCDCKPGYRFTSTGQCNDRNECQEIPNICS 296
Query: 424 GGTCVNTDGSYRCDCPPGLTLDSTGT 449
G C++T GS+ C C G + T
Sbjct: 297 HGQCIDTVGSFYCLCHTGFKTNDDQT 322
Score = 35.1 bits (77), Expect = 0.51
Identities = 14/38 (36%), Positives = 18/38 (47%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDV 39
T G+C NG C N G + C C G+ + C DV
Sbjct: 732 TKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDV 769
>AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein.
Length = 697
Score = 249 bits (610), Expect = 1e-65
Identities = 157/477 (32%), Positives = 220/477 (46%), Gaps = 55/477 (11%)
Query: 3 NGGMCTNGICKNIDGGFECI-CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C + C N G ++C+ C G+ G G C DVDEC + P VC G C N GSY
Sbjct: 131 NPSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDVDECLE-PNVCANGDCSNLEGSY 187
Query: 62 TCLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C G+ T +C D+DEC ++C G+C N+EGSF+C C GY+ +A + C D
Sbjct: 188 MCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED 247
Query: 121 VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPA-QG 177
+DEC+ + +C +G+C NT GSF+C C G+ S G C + L CQ
Sbjct: 248 IDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT 307
Query: 178 SELYAVLCPEGPSKDNGGA--DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDADG 234
+ Y CP+G D+ DINEC PG C P G C N E + C+C G+ ADG
Sbjct: 308 AGSYDCTCPDGFQLDDNKTCQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADG 366
Query: 235 -LCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE------G 286
C DIDEC ++ + C + G C NTAGSF C+C +G + + Q C D++ECE G
Sbjct: 367 RTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 425
Query: 287 ETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCL 346
E +E + L D + + G +C LD +
Sbjct: 426 EAFCENVEGSF--------------LCVCADENQEYSPMTG-QCRSRTSTDLDVDVDQPK 470
Query: 347 DNRRGSCWRRVVDGQ-CEAAAPELLLRQECCCSVGLAWGS---------XXXXXXXXXXX 396
+ ++ C+ + D C+ + +QECCC+ G+ WG
Sbjct: 471 EEKK-ECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCP 529
Query: 397 XXKGF-------AKLDGATCRDVDECAL-SAELCAGGTCVNTDGSYRCDCPPGLTLD 445
KGF ++ G +D DEC L E+C G C+NT Y C C G D
Sbjct: 530 KGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 586
Score = 243 bits (594), Expect = 1e-63
Identities = 160/466 (34%), Positives = 213/466 (45%), Gaps = 62/466 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ + CIC GY + C D+DEC +C +GRC NT GS+
Sbjct: 7 NPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFL 66
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQC-VCEAGYRPTATRGACVD 120
C+C GF + G C DVDEC +C G CVN+ G+F+C C++GYR T RG C D
Sbjct: 67 CICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT-QRGRCED 125
Query: 121 VDECEEQRVCRNGRCHNTPGSFRC-ECLPGFTLSN----DGRTCLGLKLGWGVSCQACPA 175
+DEC C + +C N+PGS++C C GF N D CL + C
Sbjct: 126 IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCS--NL 183
Query: 176 QGSELYAVLCPEGPSK--DNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH-PD 231
+GS Y C +G ++ D+ DI+EC C +G C+N E +RC C GY
Sbjct: 184 EGS--YMCSCHKGYTRTPDHKHCRDIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSA 240
Query: 232 ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETET 290
A C DIDEC H+ CA GQCRNT GSF CVC +G R C DI+EC E ++
Sbjct: 241 AKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC 299
Query: 291 HYIESDYERGDIPPTFPTRTEL--------ASPCDN-------GRCINTHGGFECECELG 335
+ G T P +L + C++ G C+NT G F C C+ G
Sbjct: 300 QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQG 359
Query: 336 YVLDATAQRCLDNRRGSCWRRVV---DGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
+ + A + C D C V G C+ A C C G
Sbjct: 360 FSISADGRTCED--IDECVNNTVCDSHGFCDNTAGSF----RCLCYQGFQ---------- 403
Query: 393 XXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A DG C DV+EC L + +C C N +GS+ C C
Sbjct: 404 ---------APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 440
Score = 231 bits (566), Expect = 3e-60
Identities = 153/470 (32%), Positives = 212/470 (45%), Gaps = 42/470 (8%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C N++G + C C GY + CRD+DEC+ +C G+C+NT GS+ C C
Sbjct: 174 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCTC 232
Query: 66 EPGFAPTAA-GYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ +AA C D+DEC +C G+C N+EGSFQCVC+ GYR + C D++EC
Sbjct: 233 GQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC 292
Query: 125 -EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ---ACPAQGSEL 180
E++ VC+ G C NT GS+ C C GF L +D +TC + C+ C QG L
Sbjct: 293 LEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDIN-----ECEHPGLCGPQGECL 346
Query: 181 -----YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
+ +C +G S G DI+EC HG C+N +RC+C G+
Sbjct: 347 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ 406
Query: 233 DGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCP-EGTRHEPELQLCR-----DIDECE 285
DG C D++EC++ C C N GSF CVC E + P CR D+D
Sbjct: 407 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV 466
Query: 286 GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECEL-GYVLDATAQ 343
+ + E Y D LA C T G G+ CE+ + TA+
Sbjct: 467 DQPKEEKKECYYNLNDASLC---DNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAE 523
Query: 344 RCLDNRRGSCWRRVVDGQCEAA------APELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
+G + + EA A E LL + C G +
Sbjct: 524 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT 583
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
KL C D+DEC C G CVNT+GSY C C + LD++
Sbjct: 584 YYDPVKLQ---CFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPMVLDAS 629
Score = 225 bits (550), Expect = 3e-58
Identities = 151/438 (34%), Positives = 191/438 (43%), Gaps = 58/438 (13%)
Query: 39 VDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDECA-ADSMCKGGRCVN 96
++EC NP +C G C N YTC+C G+ C D+DEC +C GRC N
Sbjct: 1 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN 60
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCE-CLPGFTLSND 155
+EGSF C+C AG+ + C+DVDEC VC G C NT G+FRCE C G+ ++
Sbjct: 61 TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQR 120
Query: 156 GRTCLGLKLGWGVS-C--QACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGACPHG 211
GR C + S C + C V C EG NG D++EC P C +G
Sbjct: 121 GR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PNVCANG 178
Query: 212 SCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR 270
C NLE Y C C GY D CRDIDEC + C GQC+NT GSF C C +G +
Sbjct: 179 DCSNLEGSYMCSCHKGYTRTPDHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGYQ 237
Query: 271 HEPELQLCRDIDECE-------GE---TETHY---IESDYER---GDIPPTFPTRTELAS 314
C DIDEC+ G+ TE + + Y GD E S
Sbjct: 238 LSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKS 297
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRRGSCWRRVVDGQCEAAAPELL 370
C G CINT G ++C C G+ LD + C D G C + G+C
Sbjct: 298 VCQRGDCINTAGSYDCTCPDGFQLDDN-KTCQDINECEHPGLCGPQ---GECLNTEGSF- 352
Query: 371 LRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNT 430
C C G + DG TC D+DEC + + G C NT
Sbjct: 353 ---HCVCQQGFS-------------------ISADGRTCEDIDECVNNTVCDSHGFCDNT 390
Query: 431 DGSYRCDCPPGLTLDSTG 448
GS+RC C G G
Sbjct: 391 AGSFRCLCYQGFQAPQDG 408
Score = 187 bits (456), Expect = 6e-47
Identities = 121/378 (32%), Positives = 160/378 (42%), Gaps = 60/378 (15%)
Query: 80 VDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCHN 137
++EC + +C G C+N + C+C GYR + + CVD+DEC + Q +C GRC N
Sbjct: 1 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN 60
Query: 138 TPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQA-CPAQGSELYAVLCPEGPSKDNG 194
T GSF C C GF S +G C+ + L V + C C G
Sbjct: 61 TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQR 120
Query: 195 GA--DINECTAVPGACPHGSCENLEPGYRCI-CDPGYHPDADGLCRDIDECDMHQSYCAG 251
G DI+EC P CP C N Y+C+ C G+ +G C D+DEC + + CA
Sbjct: 121 GRCEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQCLDVDEC-LEPNVCAN 177
Query: 252 GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
G C N GS+ C C +G P+ + CRDIDEC+ +G++
Sbjct: 178 GDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ-------------QGNL--------- 215
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLL 371
C NG+C NT G F C C GY L A +C D GQC
Sbjct: 216 ----CVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSF-- 269
Query: 372 RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTD 431
+C C G G G C D++EC +C G C+NT
Sbjct: 270 --QCVCDQGYR---------------ASGL----GDHCEDINECLEDKSVCQRGDCINTA 308
Query: 432 GSYRCDCPPGLTLDSTGT 449
GSY C CP G LD T
Sbjct: 309 GSYDCTCPDGFQLDDNKT 326
Score = 161 bits (392), Expect = 3e-39
Identities = 103/290 (35%), Positives = 139/290 (47%), Gaps = 35/290 (12%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G+C G C N +G F C+C+ G+ ++G C D+DEC +N G C NTAGS+ C
Sbjct: 337 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRC 396
Query: 64 LCEPGF-APTAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVC-EAGYRPTATRGAC-- 118
LC GF AP C DV+EC S +C C N EGSF CVC + + G C
Sbjct: 397 LCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRS 456
Query: 119 -------VDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC 170
VDVD+ EE++ C +N + C+ + ++ C +GWG +C
Sbjct: 457 RTSTDLDVDVDQPKEEKKECY----YNLNDASLCDNVLAPNVTKQ-ECCCTSGVGWGDNC 511
Query: 171 QA--CPAQGSELYAVLCPEGP--------SKDNGGA---DINECTAV-PGACPHGSCENL 216
+ CP G+ + +CP+G S + GG D +EC C +G C N
Sbjct: 512 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT 571
Query: 217 EPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
PGY C C G + D L C D+DEC S C GQC NT GS+ C C
Sbjct: 572 RPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFC 620
Score = 75.4 bits (177), Expect = 4e-13
Identities = 51/163 (31%), Positives = 72/163 (44%), Gaps = 10/163 (6%)
Query: 25 PGYESGSE--GALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADV 80
P ES SE G +D DEC +C+ G C NT Y C C+ G + C D+
Sbjct: 536 PAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDM 595
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV----DVDECEEQRVCRNGRCH 136
DEC S C G+CVN+EGS+ C C A+ C+ ++ EE V ++
Sbjct: 596 DECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWE 655
Query: 137 NTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+ + C L G + CL + WG+ C CP + S
Sbjct: 656 HLSDEYVCSRPLVGKQTTYTECCCLYGE-AWGMQCALCPLKDS 697
Score = 69.7 bits (163), Expect = 2e-11
Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 11/163 (6%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAG 59
+ + +C N + N+ EC C G G + V + +C +G+ AG
Sbjct: 480 LNDASLCDNVLAPNVTKQ-ECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAG 538
Query: 60 SYTCLCEPGFAPTAAGYCADVDECA--ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ E G Y D DEC +CK G C+N+ ++C C+ G +
Sbjct: 539 ESSS--EAG----GENY-KDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQ 591
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
C D+DEC++ C +G+C NT GS+ C C L + C+
Sbjct: 592 CFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI 634
Score = 48.4 bits (110), Expect = 5e-05
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 14/85 (16%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCL------------DNRRGSCWRRVVDGQ 361
S C +G+C+NT G + C C VLDA+ +RC+ D + CW + D
Sbjct: 602 SSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEY 661
Query: 362 -C-EAAAPELLLRQECCCSVGLAWG 384
C + ECCC G AWG
Sbjct: 662 VCSRPLVGKQTTYTECCCLYGEAWG 686
>M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.
Length = 1394
Score = 248 bits (608), Expect = 2e-65
Identities = 157/477 (32%), Positives = 219/477 (45%), Gaps = 55/477 (11%)
Query: 3 NGGMCTNGICKNIDGGFECI-CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C + C N G ++C+ C G+ G G C DVDEC + P VC G C N GSY
Sbjct: 677 NPSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDVDECLE-PNVCANGDCSNLEGSY 733
Query: 62 TCLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C G+ T +C D+DEC ++C G+C N+EGSF+C C GY+ +A + C D
Sbjct: 734 MCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED 793
Query: 121 VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPA-QG 177
+DEC+ + +C +G+C NT GSF+C C G+ S G C + L CQ
Sbjct: 794 IDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT 853
Query: 178 SELYAVLCPEGPSKDNGGA--DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDADG 234
+ Y CP+G D+ DINEC PG C P G C N E + C+C G+ ADG
Sbjct: 854 AGSYDCTCPDGFQLDDNKTCQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADG 912
Query: 235 -LCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE------G 286
C DIDEC ++ + C + G C NTAGSF C+C +G + + Q C D++ECE G
Sbjct: 913 RTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 971
Query: 287 ETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCL 346
E +E + L D + + G +C LD +
Sbjct: 972 EAFCENVEGSF--------------LCVCADENQEYSPMTG-QCRSRTSTDLDVDVDQPK 1016
Query: 347 DNRRGSCWRRVVDGQ-CEAAAPELLLRQECCCSVGLAWGS---------XXXXXXXXXXX 396
+ ++ C+ + D C+ + +QECCC+ G WG
Sbjct: 1017 EEKK-ECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCP 1075
Query: 397 XXKGF-------AKLDGATCRDVDECAL-SAELCAGGTCVNTDGSYRCDCPPGLTLD 445
KGF ++ G +D DEC L E+C G C+NT Y C C G D
Sbjct: 1076 KGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 1132
Score = 243 bits (594), Expect = 1e-63
Identities = 160/466 (34%), Positives = 213/466 (45%), Gaps = 62/466 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ + CIC GY + C D+DEC +C +GRC NT GS+
Sbjct: 553 NPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFL 612
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQC-VCEAGYRPTATRGACVD 120
C+C GF + G C DVDEC +C G CVN+ G+F+C C++GYR T RG C D
Sbjct: 613 CICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT-QRGRCED 671
Query: 121 VDECEEQRVCRNGRCHNTPGSFRC-ECLPGFTLSN----DGRTCLGLKLGWGVSCQACPA 175
+DEC C + +C N+PGS++C C GF N D CL + C
Sbjct: 672 IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCS--NL 729
Query: 176 QGSELYAVLCPEGPSK--DNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH-PD 231
+GS Y C +G ++ D+ DI+EC C +G C+N E +RC C GY
Sbjct: 730 EGS--YMCSCHKGYTRTPDHKHCRDIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSA 786
Query: 232 ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETET 290
A C DIDEC H+ CA GQCRNT GSF CVC +G R C DI+EC E ++
Sbjct: 787 AKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC 845
Query: 291 HYIESDYERGDIPPTFPTRTEL--------ASPCDN-------GRCINTHGGFECECELG 335
+ G T P +L + C++ G C+NT G F C C+ G
Sbjct: 846 QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQG 905
Query: 336 YVLDATAQRCLDNRRGSCWRRVV---DGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
+ + A + C D C V G C+ A C C G
Sbjct: 906 FSISADGRTCED--IDECVNNTVCDSHGFCDNTAGSF----RCLCYQGFQ---------- 949
Query: 393 XXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A DG C DV+EC L + +C C N +GS+ C C
Sbjct: 950 ---------APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 986
Score = 231 bits (566), Expect = 3e-60
Identities = 153/470 (32%), Positives = 212/470 (45%), Gaps = 42/470 (8%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C N++G + C C GY + CRD+DEC+ +C G+C+NT GS+ C C
Sbjct: 720 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCTC 778
Query: 66 EPGFAPTAA-GYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ +AA C D+DEC +C G+C N+EGSFQCVC+ GYR + C D++EC
Sbjct: 779 GQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC 838
Query: 125 -EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ---ACPAQGSEL 180
E++ VC+ G C NT GS+ C C GF L +D +TC + C+ C QG L
Sbjct: 839 LEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDIN-----ECEHPGLCGPQGECL 892
Query: 181 -----YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
+ +C +G S G DI+EC HG C+N +RC+C G+
Sbjct: 893 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ 952
Query: 233 DGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCP-EGTRHEPELQLCR-----DIDECE 285
DG C D++EC++ C C N GSF CVC E + P CR D+D
Sbjct: 953 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV 1012
Query: 286 GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECEL-GYVLDATAQ 343
+ + E Y D LA C T G G+ CE+ + TA+
Sbjct: 1013 DQPKEEKKECYYNLNDASLC---DNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAE 1069
Query: 344 RCLDNRRGSCWRRVVDGQCEAA------APELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
+G + + EA A E LL + C G +
Sbjct: 1070 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT 1129
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
KL C D+DEC C G CVNT+GSY C C + LD++
Sbjct: 1130 YYDPVKLQ---CFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPMVLDAS 1175
Score = 226 bits (552), Expect = 1e-58
Identities = 151/439 (34%), Positives = 192/439 (43%), Gaps = 58/439 (13%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDECA-ADSMCKGGRCV 95
+++EC NP +C G C N YTC+C G+ C D+DEC +C GRC
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 96 NSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCE-CLPGFTLSN 154
N+EGSF C+C AG+ + C+DVDEC VC G C NT G+FRCE C G+ ++
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 665
Query: 155 DGRTCLGLKLGWGVS-C--QACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGACPH 210
GR C + S C + C V C EG NG D++EC P C +
Sbjct: 666 RGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PNVCAN 723
Query: 211 GSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT 269
G C NLE Y C C GY D CRDIDEC + C GQC+NT GSF C C +G
Sbjct: 724 GDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGY 782
Query: 270 RHEPELQLCRDIDECE-------GE---TETHY---IESDYER---GDIPPTFPTRTELA 313
+ C DIDEC+ G+ TE + + Y GD E
Sbjct: 783 QLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDK 842
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRRGSCWRRVVDGQCEAAAPEL 369
S C G CINT G ++C C G+ LD + C D G C + G+C
Sbjct: 843 SVCQRGDCINTAGSYDCTCPDGFQLDDN-KTCQDINECEHPGLCGPQ---GECLNTEGSF 898
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + DG TC D+DEC + + G C N
Sbjct: 899 ----HCVCQQGFS-------------------ISADGRTCEDIDECVNNTVCDSHGFCDN 935
Query: 430 TDGSYRCDCPPGLTLDSTG 448
T GS+RC C G G
Sbjct: 936 TAGSFRCLCYQGFQAPQDG 954
Score = 188 bits (458), Expect = 4e-47
Identities = 121/379 (31%), Positives = 161/379 (42%), Gaps = 60/379 (15%)
Query: 79 DVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCH 136
+++EC + +C G C+N + C+C GYR + + CVD+DEC + Q +C GRC
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQA-CPAQGSELYAVLCPEGPSKDN 193
NT GSF C C GF S +G C+ + L V + C C G
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 665
Query: 194 GGA--DINECTAVPGACPHGSCENLEPGYRCI-CDPGYHPDADGLCRDIDECDMHQSYCA 250
G DI+EC P CP C N Y+C+ C G+ +G C D+DEC + + CA
Sbjct: 666 RGRCEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQCLDVDEC-LEPNVCA 722
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G C N GS+ C C +G P+ + CRDIDEC+ +G++
Sbjct: 723 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ-------------QGNL-------- 761
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELL 370
C NG+C NT G F C C GY L A +C D GQC
Sbjct: 762 -----CVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSF- 815
Query: 371 LRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNT 430
+C C G G G C D++EC +C G C+NT
Sbjct: 816 ---QCVCDQGYR---------------ASGL----GDHCEDINECLEDKSVCQRGDCINT 853
Query: 431 DGSYRCDCPPGLTLDSTGT 449
GSY C CP G LD T
Sbjct: 854 AGSYDCTCPDGFQLDDNKT 872
Score = 161 bits (390), Expect = 6e-39
Identities = 103/290 (35%), Positives = 138/290 (47%), Gaps = 35/290 (12%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G+C G C N +G F C+C+ G+ ++G C D+DEC +N G C NTAGS+ C
Sbjct: 883 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRC 942
Query: 64 LCEPGF-APTAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVC-EAGYRPTATRGAC-- 118
LC GF AP C DV+EC S +C C N EGSF CVC + + G C
Sbjct: 943 LCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRS 1002
Query: 119 -------VDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC 170
VDVD+ EE++ C +N + C+ + ++ C GWG +C
Sbjct: 1003 RTSTDLDVDVDQPKEEKKECY----YNLNDASLCDNVLAPNVTKQ-ECCCTSGAGWGDNC 1057
Query: 171 QA--CPAQGSELYAVLCPEGP--------SKDNGGA---DINECTAV-PGACPHGSCENL 216
+ CP G+ + +CP+G S + GG D +EC C +G C N
Sbjct: 1058 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT 1117
Query: 217 EPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
PGY C C G + D L C D+DEC S C GQC NT GS+ C C
Sbjct: 1118 RPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFC 1166
Score = 95.9 bits (228), Expect = 3e-19
Identities = 89/327 (27%), Positives = 129/327 (39%), Gaps = 52/327 (15%)
Query: 25 PGYESGSE--GALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADV 80
P ES SE G +D DEC +C+ G C NT Y C C+ G + C D+
Sbjct: 1082 PAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDM 1141
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV----DVDECEEQRVCRNGRCH 136
DEC S C G+CVN+EGS+ C C A+ C+ ++ EE V ++
Sbjct: 1142 DECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWE 1201
Query: 137 NTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC--PEGPSKDN 193
+ + C L G + CL + WG+ C CP + S+ YA LC P +
Sbjct: 1202 HLSDEYVCSRPLVGKQTTYTECCCLYGE-AWGMQCALCPLKDSDDYAQLCNIPVTGRRQP 1260
Query: 194 GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDI--DECDMHQSYCA 250
G D + + Y DP + D ++ +EC + C
Sbjct: 1261 YGRD--------------ALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CE 1305
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G+C +TC C +G + C D++EC+ R
Sbjct: 1306 NGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECD-------------------ELNNRM 1346
Query: 311 ELASPCDNGRCINTHGGFECECELGYV 337
L C N +CINT G ++C C GYV
Sbjct: 1347 SL---CKNAKCINTDGSYKCLCLPGYV 1370
Score = 74.9 bits (176), Expect = 5e-13
Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE----QRVCRNGRCH 136
+EC + C+ GRCV + + C C GY + C DV+EC+E +C+N +C
Sbjct: 1296 EECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKNAKCI 1355
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGL 162
NT GS++C CLPG+ S+ C L
Sbjct: 1356 NTDGSYKCLCLPGYVPSDKPNYCTPL 1381
Score = 73.7 bits (173), Expect = 1e-12
Identities = 36/125 (28%), Positives = 60/125 (48%), Gaps = 6/125 (4%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV-DVDE 123
C PG+ +C D++EC +C G C+N+ GS++C C+ G+ P T +CV D
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
E++ G C+ S R +C+ ++ + C G C+ CP G+ +
Sbjct: 346 ISEEK----GPCYRLVSSGR-QCMYPLSVHLTKQLCCCSVGKAGPHCEKCPLPGTAAFKE 400
Query: 184 LCPEG 188
+CP G
Sbjct: 401 ICPGG 405
Score = 69.3 bits (162), Expect = 3e-11
Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 11/163 (6%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAG 59
+ + +C N + N+ EC C G G + V + +C +G+ AG
Sbjct: 1026 LNDASLCDNVLAPNVTKQ-ECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAG 1084
Query: 60 SYTCLCEPGFAPTAAGYCADVDECA--ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ E G Y D DEC +CK G C+N+ ++C C+ G +
Sbjct: 1085 ESSS--EAG----GENY-KDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQ 1137
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
C D+DEC++ C +G+C NT GS+ C C L + C+
Sbjct: 1138 CFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI 1180
Score = 68.1 bits (159), Expect = 6e-11
Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 4/79 (5%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRV--CRRGRCRNTAGSYTC 63
C NG C + G+ C C GY + C DV+EC + N R+ C+ +C NT GSY C
Sbjct: 1304 CENGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKNAKCINTDGSYKC 1363
Query: 64 LCEPGFAPT-AAGYCADVD 81
LC PG+ P+ YC ++
Sbjct: 1364 LCLPGYVPSDKPNYCTPLN 1382
Score = 67.3 bits (157), Expect = 1e-10
Identities = 33/106 (31%), Positives = 50/106 (47%), Gaps = 10/106 (9%)
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG---------SXXXXXXXXXXXXXKGF 401
G C++ + QC A P L +++CC +VG +WG G+
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY 290
Query: 402 AKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
+++ C+D++EC L +C G C+NT GSYRC C G D T
Sbjct: 291 KRVNNTFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPT 335
Score = 62.9 bits (146), Expect = 2e-09
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Query: 49 CRRGRCRNTAGSYTCLCEPGF-APTAAGYCADVDECAA----DSMCKGGRCVNSEGSFQC 103
C GRC YTC C G+ TA C DV+EC S+CK +C+N++GS++C
Sbjct: 1304 CENGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKNAKCINTDGSYKC 1363
Query: 104 VCEAGYRPTATRGACVDVD 122
+C GY P+ C ++
Sbjct: 1364 LCLPGYVPSDKPNYCTPLN 1382
Score = 61.3 bits (142), Expect = 7e-09
Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRC------LDNRRGSCWRRVVDG-QCE 363
+L C NG C+NT G + C C++G+ D T C + +G C+R V G QC
Sbjct: 305 QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCM 364
Query: 364 AAAPELLLRQECCCSVGLA 382
L +Q CCCSVG A
Sbjct: 365 YPLSVHLTKQLCCCSVGKA 383
Score = 57.2 bits (132), Expect = 1e-07
Identities = 40/106 (37%), Positives = 50/106 (47%), Gaps = 10/106 (9%)
Query: 133 GRC-HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQACPAQGS-ELYAVL--CPE 187
GRC T GS + LPG + D C + WG + CQ CP + S Y + C
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQED--CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
Query: 188 GPSKDNGG--ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
G + N DINEC + G CP+G C N YRC C G+ PD
Sbjct: 289 GYKRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPD 333
Score = 52.4 bits (120), Expect = 3e-06
Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
C PGY + C+DI+EC + Q C G+C NT GS+ C C G +P C
Sbjct: 286 CLPGYKRVNNTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 50.8 bits (116), Expect = 1e-05
Identities = 22/49 (44%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C PGY+ + C+D++EC+ VC G C NT GSY C C+ GF P
Sbjct: 286 CLPGYKRVNN-TFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGP 332
Score = 48.4 bits (110), Expect = 5e-05
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 14/85 (16%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCL------------DNRRGSCWRRVVDGQ 361
S C +G+C+NT G + C C VLDA+ +RC+ D + CW + D
Sbjct: 1148 SSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEY 1207
Query: 362 -C-EAAAPELLLRQECCCSVGLAWG 384
C + ECCC G AWG
Sbjct: 1208 VCSRPLVGKQTTYTECCCLYGEAWG 1232
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/37 (54%), Positives = 24/37 (64%), Gaps = 3/37 (8%)
Query: 408 TCRDVDEC-ALS--AELCAGGTCVNTDGSYRCDCPPG 441
TC DV+EC L+ LC C+NTDGSY+C C PG
Sbjct: 1332 TCFDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1368
Score = 41.1 bits (92), Expect = 0.008
Identities = 14/32 (43%), Positives = 18/32 (56%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLD 347
C+NGRC+ G+ C+C GY LD C D
Sbjct: 1304 CENGRCVRVQEGYTCDCLDGYHLDTAKMTCFD 1335
Score = 36.7 bits (81), Expect = 0.17
Identities = 16/48 (33%), Positives = 24/48 (50%), Gaps = 4/48 (8%)
Query: 197 DINECTAVPGA---CPHGSCENLEPGYRCICDPGYHP-DADGLCRDID 240
D+NEC + C + C N + Y+C+C PGY P D C ++
Sbjct: 1335 DVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1382
Score = 36.3 bits (80), Expect = 0.22
Identities = 12/31 (38%), Positives = 17/31 (54%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALC 36
+C N C N DG ++C+C PGY + C
Sbjct: 1348 LCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1378
Score = 32.3 bits (70), Expect = 3.6
Identities = 11/23 (47%), Positives = 14/23 (60%)
Query: 5 GMCTNGICKNIDGGFECICKPGY 27
G+C NG C N G + C CK G+
Sbjct: 308 GVCPNGECLNTMGSYRCTCKIGF 330
>BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming growth
factor beta binding protein 1 protein.
Length = 1395
Score = 248 bits (608), Expect = 2e-65
Identities = 157/477 (32%), Positives = 219/477 (45%), Gaps = 55/477 (11%)
Query: 3 NGGMCTNGICKNIDGGFECI-CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C + C N G ++C+ C G+ G G C DVDEC + P VC G C N GSY
Sbjct: 678 NPSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDVDECLE-PNVCANGDCSNLEGSY 734
Query: 62 TCLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C G+ T +C D+DEC ++C G+C N+EGSF+C C GY+ +A + C D
Sbjct: 735 MCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED 794
Query: 121 VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPA-QG 177
+DEC+ + +C +G+C NT GSF+C C G+ S G C + L CQ
Sbjct: 795 IDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT 854
Query: 178 SELYAVLCPEGPSKDNGGA--DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDADG 234
+ Y CP+G D+ DINEC PG C P G C N E + C+C G+ ADG
Sbjct: 855 AGSYDCTCPDGFQLDDNKTCQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADG 913
Query: 235 -LCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE------G 286
C DIDEC ++ + C + G C NTAGSF C+C +G + + Q C D++ECE G
Sbjct: 914 RTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 972
Query: 287 ETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCL 346
E +E + L D + + G +C LD +
Sbjct: 973 EAFCENVEGSF--------------LCVCADENQEYSPMTG-QCRSRTSTDLDVDVDQPK 1017
Query: 347 DNRRGSCWRRVVDGQ-CEAAAPELLLRQECCCSVGLAWGS---------XXXXXXXXXXX 396
+ ++ C+ + D C+ + +QECCC+ G WG
Sbjct: 1018 EEKK-ECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCP 1076
Query: 397 XXKGF-------AKLDGATCRDVDECAL-SAELCAGGTCVNTDGSYRCDCPPGLTLD 445
KGF ++ G +D DEC L E+C G C+NT Y C C G D
Sbjct: 1077 KGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 1133
Score = 243 bits (594), Expect = 1e-63
Identities = 160/466 (34%), Positives = 213/466 (45%), Gaps = 62/466 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ + CIC GY + C D+DEC +C +GRC NT GS+
Sbjct: 554 NPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFL 613
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQC-VCEAGYRPTATRGACVD 120
C+C GF + G C DVDEC +C G CVN+ G+F+C C++GYR T RG C D
Sbjct: 614 CICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT-QRGRCED 672
Query: 121 VDECEEQRVCRNGRCHNTPGSFRC-ECLPGFTLSN----DGRTCLGLKLGWGVSCQACPA 175
+DEC C + +C N+PGS++C C GF N D CL + C
Sbjct: 673 IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCS--NL 730
Query: 176 QGSELYAVLCPEGPSK--DNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH-PD 231
+GS Y C +G ++ D+ DI+EC C +G C+N E +RC C GY
Sbjct: 731 EGS--YMCSCHKGYTRTPDHKHCRDIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSA 787
Query: 232 ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETET 290
A C DIDEC H+ CA GQCRNT GSF CVC +G R C DI+EC E ++
Sbjct: 788 AKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC 846
Query: 291 HYIESDYERGDIPPTFPTRTEL--------ASPCDN-------GRCINTHGGFECECELG 335
+ G T P +L + C++ G C+NT G F C C+ G
Sbjct: 847 QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQG 906
Query: 336 YVLDATAQRCLDNRRGSCWRRVV---DGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
+ + A + C D C V G C+ A C C G
Sbjct: 907 FSISADGRTCED--IDECVNNTVCDSHGFCDNTAGSF----RCLCYQGFQ---------- 950
Query: 393 XXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A DG C DV+EC L + +C C N +GS+ C C
Sbjct: 951 ---------APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 987
Score = 231 bits (566), Expect = 3e-60
Identities = 153/470 (32%), Positives = 212/470 (45%), Gaps = 42/470 (8%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C N++G + C C GY + CRD+DEC+ +C G+C+NT GS+ C C
Sbjct: 721 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCTC 779
Query: 66 EPGFAPTAA-GYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ +AA C D+DEC +C G+C N+EGSFQCVC+ GYR + C D++EC
Sbjct: 780 GQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC 839
Query: 125 -EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ---ACPAQGSEL 180
E++ VC+ G C NT GS+ C C GF L +D +TC + C+ C QG L
Sbjct: 840 LEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDIN-----ECEHPGLCGPQGECL 893
Query: 181 -----YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
+ +C +G S G DI+EC HG C+N +RC+C G+
Sbjct: 894 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ 953
Query: 233 DGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCP-EGTRHEPELQLCR-----DIDECE 285
DG C D++EC++ C C N GSF CVC E + P CR D+D
Sbjct: 954 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV 1013
Query: 286 GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECEL-GYVLDATAQ 343
+ + E Y D LA C T G G+ CE+ + TA+
Sbjct: 1014 DQPKEEKKECYYNLNDASLC---DNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAE 1070
Query: 344 RCLDNRRGSCWRRVVDGQCEAA------APELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
+G + + EA A E LL + C G +
Sbjct: 1071 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT 1130
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
KL C D+DEC C G CVNT+GSY C C + LD++
Sbjct: 1131 YYDPVKLQ---CFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPMVLDAS 1176
Score = 226 bits (552), Expect = 1e-58
Identities = 151/439 (34%), Positives = 192/439 (43%), Gaps = 58/439 (13%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDECA-ADSMCKGGRCV 95
+++EC NP +C G C N YTC+C G+ C D+DEC +C GRC
Sbjct: 547 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 606
Query: 96 NSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCE-CLPGFTLSN 154
N+EGSF C+C AG+ + C+DVDEC VC G C NT G+FRCE C G+ ++
Sbjct: 607 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 666
Query: 155 DGRTCLGLKLGWGVS-C--QACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGACPH 210
GR C + S C + C V C EG NG D++EC P C +
Sbjct: 667 RGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PNVCAN 724
Query: 211 GSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT 269
G C NLE Y C C GY D CRDIDEC + C GQC+NT GSF C C +G
Sbjct: 725 GDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGY 783
Query: 270 RHEPELQLCRDIDECE-------GE---TETHY---IESDYER---GDIPPTFPTRTELA 313
+ C DIDEC+ G+ TE + + Y GD E
Sbjct: 784 QLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDK 843
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRRGSCWRRVVDGQCEAAAPEL 369
S C G CINT G ++C C G+ LD + C D G C + G+C
Sbjct: 844 SVCQRGDCINTAGSYDCTCPDGFQLDDN-KTCQDINECEHPGLCGPQ---GECLNTEGSF 899
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + DG TC D+DEC + + G C N
Sbjct: 900 ----HCVCQQGFS-------------------ISADGRTCEDIDECVNNTVCDSHGFCDN 936
Query: 430 TDGSYRCDCPPGLTLDSTG 448
T GS+RC C G G
Sbjct: 937 TAGSFRCLCYQGFQAPQDG 955
Score = 188 bits (458), Expect = 4e-47
Identities = 121/379 (31%), Positives = 161/379 (42%), Gaps = 60/379 (15%)
Query: 79 DVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCH 136
+++EC + +C G C+N + C+C GYR + + CVD+DEC + Q +C GRC
Sbjct: 547 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 606
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQA-CPAQGSELYAVLCPEGPSKDN 193
NT GSF C C GF S +G C+ + L V + C C G
Sbjct: 607 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 666
Query: 194 GGA--DINECTAVPGACPHGSCENLEPGYRCI-CDPGYHPDADGLCRDIDECDMHQSYCA 250
G DI+EC P CP C N Y+C+ C G+ +G C D+DEC + + CA
Sbjct: 667 RGRCEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQCLDVDEC-LEPNVCA 723
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G C N GS+ C C +G P+ + CRDIDEC+ +G++
Sbjct: 724 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ-------------QGNL-------- 762
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELL 370
C NG+C NT G F C C GY L A +C D GQC
Sbjct: 763 -----CVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSF- 816
Query: 371 LRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNT 430
+C C G G G C D++EC +C G C+NT
Sbjct: 817 ---QCVCDQGYR---------------ASGL----GDHCEDINECLEDKSVCQRGDCINT 854
Query: 431 DGSYRCDCPPGLTLDSTGT 449
GSY C CP G LD T
Sbjct: 855 AGSYDCTCPDGFQLDDNKT 873
Score = 161 bits (390), Expect = 6e-39
Identities = 103/290 (35%), Positives = 138/290 (47%), Gaps = 35/290 (12%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G+C G C N +G F C+C+ G+ ++G C D+DEC +N G C NTAGS+ C
Sbjct: 884 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRC 943
Query: 64 LCEPGF-APTAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVC-EAGYRPTATRGAC-- 118
LC GF AP C DV+EC S +C C N EGSF CVC + + G C
Sbjct: 944 LCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRS 1003
Query: 119 -------VDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC 170
VDVD+ EE++ C +N + C+ + ++ C GWG +C
Sbjct: 1004 RTSTDLDVDVDQPKEEKKECY----YNLNDASLCDNVLAPNVTKQ-ECCCTSGAGWGDNC 1058
Query: 171 QA--CPAQGSELYAVLCPEGP--------SKDNGGA---DINECTAV-PGACPHGSCENL 216
+ CP G+ + +CP+G S + GG D +EC C +G C N
Sbjct: 1059 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT 1118
Query: 217 EPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
PGY C C G + D L C D+DEC S C GQC NT GS+ C C
Sbjct: 1119 RPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFC 1167
Score = 95.5 bits (227), Expect = 3e-19
Identities = 89/327 (27%), Positives = 129/327 (39%), Gaps = 52/327 (15%)
Query: 25 PGYESGSE--GALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADV 80
P ES SE G +D DEC +C+ G C NT Y C C+ G + C D+
Sbjct: 1083 PAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDM 1142
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV----DVDECEEQRVCRNGRCH 136
DEC S C G+CVN+EGS+ C C A+ C+ ++ EE V ++
Sbjct: 1143 DECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWE 1202
Query: 137 NTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC--PEGPSKDN 193
+ + C L G + CL + WG+ C CP + S+ YA LC P +
Sbjct: 1203 HLSDEYVCSRPLVGKQTTYTECCCLYGE-AWGMQCALCPLKDSDDYAQLCNIPVTGRRQP 1261
Query: 194 GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDI--DECDMHQSYCA 250
G D + + Y DP + D ++ +EC + C
Sbjct: 1262 YGRD--------------ALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CE 1306
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G+C +TC C +G + C D++EC+ R
Sbjct: 1307 NGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECD-------------------ELNNRM 1347
Query: 311 ELASPCDNGRCINTHGGFECECELGYV 337
L C N +CINT G ++C C GYV
Sbjct: 1348 SL---CKNAKCINTDGSYKCLCLPGYV 1371
Score = 79.4 bits (187), Expect = 2e-14
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 7/126 (5%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV-DVDE 123
C PG+ +C D++EC +C G C+N+ GS++C C+ G+ P T +CV D
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTCLGLKLGWGVSCQACPAQGSELYA 182
E++ G C+ S R +C+ ++ C + WG C+ CP G+ +
Sbjct: 346 ISEEK----GPCYRLVSSGR-QCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFK 400
Query: 183 VLCPEG 188
+CP G
Sbjct: 401 EICPGG 406
Score = 77.0 bits (181), Expect = 1e-13
Identities = 33/86 (38%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE----QRVCRNGRCH 136
+EC + C+ GRCV + + C C GY + CVDV+EC+E +C+N +C
Sbjct: 1297 EECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI 1356
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGL 162
NT GS++C CLPG+ S+ C L
Sbjct: 1357 NTDGSYKCLCLPGYVPSDKPNYCTPL 1382
Score = 69.3 bits (162), Expect = 3e-11
Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 11/163 (6%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAG 59
+ + +C N + N+ EC C G G + V + +C +G+ AG
Sbjct: 1027 LNDASLCDNVLAPNVTKQ-ECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAG 1085
Query: 60 SYTCLCEPGFAPTAAGYCADVDECA--ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ E G Y D DEC +CK G C+N+ ++C C+ G +
Sbjct: 1086 ESSS--EAG----GENY-KDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQ 1138
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
C D+DEC++ C +G+C NT GS+ C C L + C+
Sbjct: 1139 CFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI 1181
Score = 68.1 bits (159), Expect = 6e-11
Identities = 32/81 (39%), Positives = 42/81 (51%), Gaps = 7/81 (8%)
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRC------LDNRRGSCWRRVVDG-QCE 363
+L C NG C+NT G + C C++G+ D T C + +G C+R V G QC
Sbjct: 305 QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCM 364
Query: 364 AAAPELLLRQECCCSVGLAWG 384
L +Q CCCSVG AWG
Sbjct: 365 HPLSVHLTKQLCCCSVGKAWG 385
Score = 67.7 bits (158), Expect = 8e-11
Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 4/79 (5%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRV--CRRGRCRNTAGSYTC 63
C NG C + G+ C C GY + C DV+EC + N R+ C+ +C NT GSY C
Sbjct: 1305 CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKC 1364
Query: 64 LCEPGFAPT-AAGYCADVD 81
LC PG+ P+ YC ++
Sbjct: 1365 LCLPGYVPSDKPNYCTPLN 1383
Score = 67.3 bits (157), Expect = 1e-10
Identities = 33/106 (31%), Positives = 50/106 (47%), Gaps = 10/106 (9%)
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG---------SXXXXXXXXXXXXXKGF 401
G C++ + QC A P L +++CC +VG +WG G+
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY 290
Query: 402 AKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
+++ C+D++EC L +C G C+NT GSYRC C G D T
Sbjct: 291 KRVNNTFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPT 335
Score = 63.7 bits (148), Expect = 1e-09
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Query: 49 CRRGRCRNTAGSYTCLCEPGF-APTAAGYCADVDECAA----DSMCKGGRCVNSEGSFQC 103
C GRC YTC C G+ TA C DV+EC S+CK +C+N++GS++C
Sbjct: 1305 CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKC 1364
Query: 104 VCEAGYRPTATRGACVDVD 122
+C GY P+ C ++
Sbjct: 1365 LCLPGYVPSDKPNYCTPLN 1383
Score = 57.2 bits (132), Expect = 1e-07
Identities = 40/106 (37%), Positives = 50/106 (47%), Gaps = 10/106 (9%)
Query: 133 GRC-HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQACPAQGS-ELYAVL--CPE 187
GRC T GS + LPG + D C + WG + CQ CP + S Y + C
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQED--CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
Query: 188 GPSKDNGG--ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
G + N DINEC + G CP+G C N YRC C G+ PD
Sbjct: 289 GYKRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPD 333
Score = 52.4 bits (120), Expect = 3e-06
Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
C PGY + C+DI+EC + Q C G+C NT GS+ C C G +P C
Sbjct: 286 CLPGYKRVNNTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 50.8 bits (116), Expect = 1e-05
Identities = 22/49 (44%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C PGY+ + C+D++EC+ VC G C NT GSY C C+ GF P
Sbjct: 286 CLPGYKRVNN-TFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGP 332
Score = 48.4 bits (110), Expect = 5e-05
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 14/85 (16%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCL------------DNRRGSCWRRVVDGQ 361
S C +G+C+NT G + C C VLDA+ +RC+ D + CW + D
Sbjct: 1149 SSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEY 1208
Query: 362 -C-EAAAPELLLRQECCCSVGLAWG 384
C + ECCC G AWG
Sbjct: 1209 VCSRPLVGKQTTYTECCCLYGEAWG 1233
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/37 (54%), Positives = 24/37 (64%), Gaps = 3/37 (8%)
Query: 408 TCRDVDEC-ALS--AELCAGGTCVNTDGSYRCDCPPG 441
TC DV+EC L+ LC C+NTDGSY+C C PG
Sbjct: 1333 TCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1369
Score = 41.5 bits (93), Expect = 0.006
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLD 347
C+NGRC+ G+ C+C GY LD C+D
Sbjct: 1305 CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVD 1336
Score = 36.7 bits (81), Expect = 0.17
Identities = 16/48 (33%), Positives = 24/48 (50%), Gaps = 4/48 (8%)
Query: 197 DINECTAVPGA---CPHGSCENLEPGYRCICDPGYHP-DADGLCRDID 240
D+NEC + C + C N + Y+C+C PGY P D C ++
Sbjct: 1336 DVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1383
Score = 36.3 bits (80), Expect = 0.22
Identities = 12/31 (38%), Positives = 17/31 (54%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALC 36
+C N C N DG ++C+C PGY + C
Sbjct: 1349 LCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1379
Score = 32.3 bits (70), Expect = 3.6
Identities = 11/23 (47%), Positives = 14/23 (60%)
Query: 5 GMCTNGICKNIDGGFECICKPGY 27
G+C NG C N G + C CK G+
Sbjct: 308 GVCPNGECLNTMGSYRCTCKIGF 330
>AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth
factor-beta binding protein-1S protein.
Length = 1394
Score = 248 bits (608), Expect = 2e-65
Identities = 157/477 (32%), Positives = 219/477 (45%), Gaps = 55/477 (11%)
Query: 3 NGGMCTNGICKNIDGGFECI-CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C + C N G ++C+ C G+ G G C DVDEC + P VC G C N GSY
Sbjct: 677 NPSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDVDECLE-PNVCANGDCSNLEGSY 733
Query: 62 TCLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C G+ T +C D+DEC ++C G+C N+EGSF+C C GY+ +A + C D
Sbjct: 734 MCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED 793
Query: 121 VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPA-QG 177
+DEC+ + +C +G+C NT GSF+C C G+ S G C + L CQ
Sbjct: 794 IDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT 853
Query: 178 SELYAVLCPEGPSKDNGGA--DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDADG 234
+ Y CP+G D+ DINEC PG C P G C N E + C+C G+ ADG
Sbjct: 854 AGSYDCTCPDGFQLDDNKTCQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADG 912
Query: 235 -LCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE------G 286
C DIDEC ++ + C + G C NTAGSF C+C +G + + Q C D++ECE G
Sbjct: 913 RTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 971
Query: 287 ETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCL 346
E +E + L D + + G +C LD +
Sbjct: 972 EAFCENVEGSF--------------LCVCADENQEYSPMTG-QCRSRTSTDLDVDVDQPK 1016
Query: 347 DNRRGSCWRRVVDGQ-CEAAAPELLLRQECCCSVGLAWGS---------XXXXXXXXXXX 396
+ ++ C+ + D C+ + +QECCC+ G WG
Sbjct: 1017 EEKK-ECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCP 1075
Query: 397 XXKGF-------AKLDGATCRDVDECAL-SAELCAGGTCVNTDGSYRCDCPPGLTLD 445
KGF ++ G +D DEC L E+C G C+NT Y C C G D
Sbjct: 1076 KGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 1132
Score = 243 bits (594), Expect = 1e-63
Identities = 160/466 (34%), Positives = 213/466 (45%), Gaps = 62/466 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ + CIC GY + C D+DEC +C +GRC NT GS+
Sbjct: 553 NPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFL 612
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQC-VCEAGYRPTATRGACVD 120
C+C GF + G C DVDEC +C G CVN+ G+F+C C++GYR T RG C D
Sbjct: 613 CICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT-QRGRCED 671
Query: 121 VDECEEQRVCRNGRCHNTPGSFRC-ECLPGFTLSN----DGRTCLGLKLGWGVSCQACPA 175
+DEC C + +C N+PGS++C C GF N D CL + C
Sbjct: 672 IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCS--NL 729
Query: 176 QGSELYAVLCPEGPSK--DNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH-PD 231
+GS Y C +G ++ D+ DI+EC C +G C+N E +RC C GY
Sbjct: 730 EGS--YMCSCHKGYTRTPDHKHCRDIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSA 786
Query: 232 ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETET 290
A C DIDEC H+ CA GQCRNT GSF CVC +G R C DI+EC E ++
Sbjct: 787 AKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC 845
Query: 291 HYIESDYERGDIPPTFPTRTEL--------ASPCDN-------GRCINTHGGFECECELG 335
+ G T P +L + C++ G C+NT G F C C+ G
Sbjct: 846 QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQG 905
Query: 336 YVLDATAQRCLDNRRGSCWRRVV---DGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
+ + A + C D C V G C+ A C C G
Sbjct: 906 FSISADGRTCED--IDECVNNTVCDSHGFCDNTAGSF----RCLCYQGFQ---------- 949
Query: 393 XXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A DG C DV+EC L + +C C N +GS+ C C
Sbjct: 950 ---------APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 986
Score = 231 bits (566), Expect = 3e-60
Identities = 153/470 (32%), Positives = 212/470 (45%), Gaps = 42/470 (8%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C N++G + C C GY + CRD+DEC+ +C G+C+NT GS+ C C
Sbjct: 720 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCTC 778
Query: 66 EPGFAPTAA-GYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ +AA C D+DEC +C G+C N+EGSFQCVC+ GYR + C D++EC
Sbjct: 779 GQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC 838
Query: 125 -EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ---ACPAQGSEL 180
E++ VC+ G C NT GS+ C C GF L +D +TC + C+ C QG L
Sbjct: 839 LEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDIN-----ECEHPGLCGPQGECL 892
Query: 181 -----YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
+ +C +G S G DI+EC HG C+N +RC+C G+
Sbjct: 893 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ 952
Query: 233 DGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCP-EGTRHEPELQLCR-----DIDECE 285
DG C D++EC++ C C N GSF CVC E + P CR D+D
Sbjct: 953 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV 1012
Query: 286 GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECEL-GYVLDATAQ 343
+ + E Y D LA C T G G+ CE+ + TA+
Sbjct: 1013 DQPKEEKKECYYNLNDASLC---DNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAE 1069
Query: 344 RCLDNRRGSCWRRVVDGQCEAA------APELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
+G + + EA A E LL + C G +
Sbjct: 1070 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT 1129
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
KL C D+DEC C G CVNT+GSY C C + LD++
Sbjct: 1130 YYDPVKLQ---CFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPMVLDAS 1175
Score = 226 bits (552), Expect = 1e-58
Identities = 151/439 (34%), Positives = 192/439 (43%), Gaps = 58/439 (13%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDECA-ADSMCKGGRCV 95
+++EC NP +C G C N YTC+C G+ C D+DEC +C GRC
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 96 NSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCE-CLPGFTLSN 154
N+EGSF C+C AG+ + C+DVDEC VC G C NT G+FRCE C G+ ++
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 665
Query: 155 DGRTCLGLKLGWGVS-C--QACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGACPH 210
GR C + S C + C V C EG NG D++EC P C +
Sbjct: 666 RGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PNVCAN 723
Query: 211 GSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT 269
G C NLE Y C C GY D CRDIDEC + C GQC+NT GSF C C +G
Sbjct: 724 GDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGY 782
Query: 270 RHEPELQLCRDIDECE-------GE---TETHY---IESDYER---GDIPPTFPTRTELA 313
+ C DIDEC+ G+ TE + + Y GD E
Sbjct: 783 QLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDK 842
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRRGSCWRRVVDGQCEAAAPEL 369
S C G CINT G ++C C G+ LD + C D G C + G+C
Sbjct: 843 SVCQRGDCINTAGSYDCTCPDGFQLDDN-KTCQDINECEHPGLCGPQ---GECLNTEGSF 898
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + DG TC D+DEC + + G C N
Sbjct: 899 ----HCVCQQGFS-------------------ISADGRTCEDIDECVNNTVCDSHGFCDN 935
Query: 430 TDGSYRCDCPPGLTLDSTG 448
T GS+RC C G G
Sbjct: 936 TAGSFRCLCYQGFQAPQDG 954
Score = 188 bits (458), Expect = 4e-47
Identities = 121/379 (31%), Positives = 161/379 (42%), Gaps = 60/379 (15%)
Query: 79 DVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCH 136
+++EC + +C G C+N + C+C GYR + + CVD+DEC + Q +C GRC
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQA-CPAQGSELYAVLCPEGPSKDN 193
NT GSF C C GF S +G C+ + L V + C C G
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 665
Query: 194 GGA--DINECTAVPGACPHGSCENLEPGYRCI-CDPGYHPDADGLCRDIDECDMHQSYCA 250
G DI+EC P CP C N Y+C+ C G+ +G C D+DEC + + CA
Sbjct: 666 RGRCEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQCLDVDEC-LEPNVCA 722
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G C N GS+ C C +G P+ + CRDIDEC+ +G++
Sbjct: 723 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ-------------QGNL-------- 761
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELL 370
C NG+C NT G F C C GY L A +C D GQC
Sbjct: 762 -----CVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSF- 815
Query: 371 LRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNT 430
+C C G G G C D++EC +C G C+NT
Sbjct: 816 ---QCVCDQGYR---------------ASGL----GDHCEDINECLEDKSVCQRGDCINT 853
Query: 431 DGSYRCDCPPGLTLDSTGT 449
GSY C CP G LD T
Sbjct: 854 AGSYDCTCPDGFQLDDNKT 872
Score = 161 bits (390), Expect = 6e-39
Identities = 103/290 (35%), Positives = 138/290 (47%), Gaps = 35/290 (12%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G+C G C N +G F C+C+ G+ ++G C D+DEC +N G C NTAGS+ C
Sbjct: 883 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRC 942
Query: 64 LCEPGF-APTAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVC-EAGYRPTATRGAC-- 118
LC GF AP C DV+EC S +C C N EGSF CVC + + G C
Sbjct: 943 LCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRS 1002
Query: 119 -------VDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC 170
VDVD+ EE++ C +N + C+ + ++ C GWG +C
Sbjct: 1003 RTSTDLDVDVDQPKEEKKECY----YNLNDASLCDNVLAPNVTKQ-ECCCTSGAGWGDNC 1057
Query: 171 QA--CPAQGSELYAVLCPEGP--------SKDNGGA---DINECTAV-PGACPHGSCENL 216
+ CP G+ + +CP+G S + GG D +EC C +G C N
Sbjct: 1058 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT 1117
Query: 217 EPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
PGY C C G + D L C D+DEC S C GQC NT GS+ C C
Sbjct: 1118 RPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFC 1166
Score = 95.9 bits (228), Expect = 3e-19
Identities = 89/327 (27%), Positives = 129/327 (39%), Gaps = 52/327 (15%)
Query: 25 PGYESGSE--GALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADV 80
P ES SE G +D DEC +C+ G C NT Y C C+ G + C D+
Sbjct: 1082 PAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDM 1141
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV----DVDECEEQRVCRNGRCH 136
DEC S C G+CVN+EGS+ C C A+ C+ ++ EE V ++
Sbjct: 1142 DECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWE 1201
Query: 137 NTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC--PEGPSKDN 193
+ + C L G + CL + WG+ C CP + S+ YA LC P +
Sbjct: 1202 HLSDEYVCSRPLVGKQTTYTECCCLYGE-AWGMQCALCPLKDSDDYAQLCNIPVTGRRQP 1260
Query: 194 GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDI--DECDMHQSYCA 250
G D + + Y DP + D ++ +EC + C
Sbjct: 1261 YGRD--------------ALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CE 1305
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G+C +TC C +G + C D++EC+ R
Sbjct: 1306 NGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECD-------------------ELNNRM 1346
Query: 311 ELASPCDNGRCINTHGGFECECELGYV 337
L C N +CINT G ++C C GYV
Sbjct: 1347 SL---CKNAKCINTDGSYKCLCLPGYV 1370
Score = 77.0 bits (181), Expect = 1e-13
Identities = 33/86 (38%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE----QRVCRNGRCH 136
+EC + C+ GRCV + + C C GY + CVDV+EC+E +C+N +C
Sbjct: 1296 EECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI 1355
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGL 162
NT GS++C CLPG+ S+ C L
Sbjct: 1356 NTDGSYKCLCLPGYVPSDKPNYCTPL 1381
Score = 74.1 bits (174), Expect = 9e-13
Identities = 36/125 (28%), Positives = 60/125 (48%), Gaps = 6/125 (4%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV-DVDE 123
C PG+ +C D++EC +C G C+N+ GS++C C+ G+ P T +CV D
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
E++ G C+ S R +C+ ++ + C G C+ CP G+ +
Sbjct: 346 ISEEK----GPCYRLVSSGR-QCMHPLSVHLTKQLCCCSVGKAGPHCEKCPLPGTAAFKE 400
Query: 184 LCPEG 188
+CP G
Sbjct: 401 ICPGG 405
Score = 69.3 bits (162), Expect = 3e-11
Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 11/163 (6%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAG 59
+ + +C N + N+ EC C G G + V + +C +G+ AG
Sbjct: 1026 LNDASLCDNVLAPNVTKQ-ECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAG 1084
Query: 60 SYTCLCEPGFAPTAAGYCADVDECA--ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ E G Y D DEC +CK G C+N+ ++C C+ G +
Sbjct: 1085 ESSS--EAG----GENY-KDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQ 1137
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
C D+DEC++ C +G+C NT GS+ C C L + C+
Sbjct: 1138 CFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI 1180
Score = 68.1 bits (159), Expect = 6e-11
Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 4/79 (5%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRV--CRRGRCRNTAGSYTC 63
C NG C + G+ C C GY + C DV+EC + N R+ C+ +C NT GSY C
Sbjct: 1304 CENGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKC 1363
Query: 64 LCEPGFAPT-AAGYCADVD 81
LC PG+ P+ YC ++
Sbjct: 1364 LCLPGYVPSDKPNYCTPLN 1382
Score = 67.3 bits (157), Expect = 1e-10
Identities = 33/106 (31%), Positives = 50/106 (47%), Gaps = 10/106 (9%)
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG---------SXXXXXXXXXXXXXKGF 401
G C++ + QC A P L +++CC +VG +WG G+
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY 290
Query: 402 AKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
+++ C+D++EC L +C G C+NT GSYRC C G D T
Sbjct: 291 KRVNNTFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPT 335
Score = 63.7 bits (148), Expect = 1e-09
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Query: 49 CRRGRCRNTAGSYTCLCEPGF-APTAAGYCADVDECAA----DSMCKGGRCVNSEGSFQC 103
C GRC YTC C G+ TA C DV+EC S+CK +C+N++GS++C
Sbjct: 1304 CENGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKC 1363
Query: 104 VCEAGYRPTATRGACVDVD 122
+C GY P+ C ++
Sbjct: 1364 LCLPGYVPSDKPNYCTPLN 1382
Score = 61.3 bits (142), Expect = 7e-09
Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRC------LDNRRGSCWRRVVDG-QCE 363
+L C NG C+NT G + C C++G+ D T C + +G C+R V G QC
Sbjct: 305 QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCM 364
Query: 364 AAAPELLLRQECCCSVGLA 382
L +Q CCCSVG A
Sbjct: 365 HPLSVHLTKQLCCCSVGKA 383
Score = 57.2 bits (132), Expect = 1e-07
Identities = 40/106 (37%), Positives = 50/106 (47%), Gaps = 10/106 (9%)
Query: 133 GRC-HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQACPAQGS-ELYAVL--CPE 187
GRC T GS + LPG + D C + WG + CQ CP + S Y + C
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQED--CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
Query: 188 GPSKDNGG--ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
G + N DINEC + G CP+G C N YRC C G+ PD
Sbjct: 289 GYKRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPD 333
Score = 52.4 bits (120), Expect = 3e-06
Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
C PGY + C+DI+EC + Q C G+C NT GS+ C C G +P C
Sbjct: 286 CLPGYKRVNNTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 50.8 bits (116), Expect = 1e-05
Identities = 22/49 (44%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C PGY+ + C+D++EC+ VC G C NT GSY C C+ GF P
Sbjct: 286 CLPGYKRVNN-TFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGP 332
Score = 48.4 bits (110), Expect = 5e-05
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 14/85 (16%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCL------------DNRRGSCWRRVVDGQ 361
S C +G+C+NT G + C C VLDA+ +RC+ D + CW + D
Sbjct: 1148 SSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEY 1207
Query: 362 -C-EAAAPELLLRQECCCSVGLAWG 384
C + ECCC G AWG
Sbjct: 1208 VCSRPLVGKQTTYTECCCLYGEAWG 1232
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/37 (54%), Positives = 24/37 (64%), Gaps = 3/37 (8%)
Query: 408 TCRDVDEC-ALS--AELCAGGTCVNTDGSYRCDCPPG 441
TC DV+EC L+ LC C+NTDGSY+C C PG
Sbjct: 1332 TCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1368
Score = 41.5 bits (93), Expect = 0.006
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLD 347
C+NGRC+ G+ C+C GY LD C+D
Sbjct: 1304 CENGRCVRVQEGYTCDCLDGYHLDTAKMTCVD 1335
Score = 36.7 bits (81), Expect = 0.17
Identities = 16/48 (33%), Positives = 24/48 (50%), Gaps = 4/48 (8%)
Query: 197 DINECTAVPGA---CPHGSCENLEPGYRCICDPGYHP-DADGLCRDID 240
D+NEC + C + C N + Y+C+C PGY P D C ++
Sbjct: 1335 DVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1382
Score = 36.3 bits (80), Expect = 0.22
Identities = 12/31 (38%), Positives = 17/31 (54%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALC 36
+C N C N DG ++C+C PGY + C
Sbjct: 1348 LCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1378
Score = 32.7 bits (71), Expect = 2.7
Identities = 27/98 (27%), Positives = 35/98 (35%), Gaps = 10/98 (10%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRR----GR-CRNTA 58
G+C NG C N G + C CK G+ + C D + C R GR C +
Sbjct: 308 GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPL 367
Query: 59 GSY----TCLCEPGFAPTAAGYCADVDECAADSMCKGG 92
+ C C G A C A +C GG
Sbjct: 368 SVHLTKQLCCCSVGKAGPHCEKCPLPGTAAFKEICPGG 405
>AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming growth
factor beta binding protein 1 isoform LTBP-1S varian
protein.
Length = 1348
Score = 248 bits (608), Expect = 2e-65
Identities = 157/477 (32%), Positives = 219/477 (45%), Gaps = 55/477 (11%)
Query: 3 NGGMCTNGICKNIDGGFECI-CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C + C N G ++C+ C G+ G G C DVDEC + P VC G C N GSY
Sbjct: 631 NPSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDVDECLE-PNVCANGDCSNLEGSY 687
Query: 62 TCLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C G+ T +C D+DEC ++C G+C N+EGSF+C C GY+ +A + C D
Sbjct: 688 MCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED 747
Query: 121 VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPA-QG 177
+DEC+ + +C +G+C NT GSF+C C G+ S G C + L CQ
Sbjct: 748 IDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT 807
Query: 178 SELYAVLCPEGPSKDNGGA--DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDADG 234
+ Y CP+G D+ DINEC PG C P G C N E + C+C G+ ADG
Sbjct: 808 AGSYDCTCPDGFQLDDNKTCQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADG 866
Query: 235 -LCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE------G 286
C DIDEC ++ + C + G C NTAGSF C+C +G + + Q C D++ECE G
Sbjct: 867 RTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 925
Query: 287 ETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCL 346
E +E + L D + + G +C LD +
Sbjct: 926 EAFCENVEGSF--------------LCVCADENQEYSPMTG-QCRSRTSTDLDVDVDQPK 970
Query: 347 DNRRGSCWRRVVDGQ-CEAAAPELLLRQECCCSVGLAWGS---------XXXXXXXXXXX 396
+ ++ C+ + D C+ + +QECCC+ G WG
Sbjct: 971 EEKK-ECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCP 1029
Query: 397 XXKGF-------AKLDGATCRDVDECAL-SAELCAGGTCVNTDGSYRCDCPPGLTLD 445
KGF ++ G +D DEC L E+C G C+NT Y C C G D
Sbjct: 1030 KGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 1086
Score = 243 bits (594), Expect = 1e-63
Identities = 160/466 (34%), Positives = 213/466 (45%), Gaps = 62/466 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C N+ + CIC GY + C D+DEC +C +GRC NT GS+
Sbjct: 507 NPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFL 566
Query: 63 CLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQC-VCEAGYRPTATRGACVD 120
C+C GF + G C DVDEC +C G CVN+ G+F+C C++GYR T RG C D
Sbjct: 567 CICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT-QRGRCED 625
Query: 121 VDECEEQRVCRNGRCHNTPGSFRC-ECLPGFTLSN----DGRTCLGLKLGWGVSCQACPA 175
+DEC C + +C N+PGS++C C GF N D CL + C
Sbjct: 626 IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCS--NL 683
Query: 176 QGSELYAVLCPEGPSK--DNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYH-PD 231
+GS Y C +G ++ D+ DI+EC C +G C+N E +RC C GY
Sbjct: 684 EGS--YMCSCHKGYTRTPDHKHCRDIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSA 740
Query: 232 ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETET 290
A C DIDEC H+ CA GQCRNT GSF CVC +G R C DI+EC E ++
Sbjct: 741 AKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC 799
Query: 291 HYIESDYERGDIPPTFPTRTEL--------ASPCDN-------GRCINTHGGFECECELG 335
+ G T P +L + C++ G C+NT G F C C+ G
Sbjct: 800 QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQG 859
Query: 336 YVLDATAQRCLDNRRGSCWRRVV---DGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
+ + A + C D C V G C+ A C C G
Sbjct: 860 FSISADGRTCED--IDECVNNTVCDSHGFCDNTAGSF----RCLCYQGFQ---------- 903
Query: 393 XXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A DG C DV+EC L + +C C N +GS+ C C
Sbjct: 904 ---------APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 940
Score = 231 bits (566), Expect = 3e-60
Identities = 153/470 (32%), Positives = 212/470 (45%), Gaps = 42/470 (8%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C N++G + C C GY + CRD+DEC+ +C G+C+NT GS+ C C
Sbjct: 674 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCTC 732
Query: 66 EPGFAPTAA-GYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ +AA C D+DEC +C G+C N+EGSFQCVC+ GYR + C D++EC
Sbjct: 733 GQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC 792
Query: 125 -EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ---ACPAQGSEL 180
E++ VC+ G C NT GS+ C C GF L +D +TC + C+ C QG L
Sbjct: 793 LEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDIN-----ECEHPGLCGPQGECL 846
Query: 181 -----YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
+ +C +G S G DI+EC HG C+N +RC+C G+
Sbjct: 847 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ 906
Query: 233 DGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCP-EGTRHEPELQLCR-----DIDECE 285
DG C D++EC++ C C N GSF CVC E + P CR D+D
Sbjct: 907 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV 966
Query: 286 GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECEL-GYVLDATAQ 343
+ + E Y D LA C T G G+ CE+ + TA+
Sbjct: 967 DQPKEEKKECYYNLNDASLC---DNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAE 1023
Query: 344 RCLDNRRGSCWRRVVDGQCEAA------APELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
+G + + EA A E LL + C G +
Sbjct: 1024 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT 1083
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
KL C D+DEC C G CVNT+GSY C C + LD++
Sbjct: 1084 YYDPVKLQ---CFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPMVLDAS 1129
Score = 226 bits (552), Expect = 1e-58
Identities = 151/439 (34%), Positives = 192/439 (43%), Gaps = 58/439 (13%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDECA-ADSMCKGGRCV 95
+++EC NP +C G C N YTC+C G+ C D+DEC +C GRC
Sbjct: 500 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 559
Query: 96 NSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCE-CLPGFTLSN 154
N+EGSF C+C AG+ + C+DVDEC VC G C NT G+FRCE C G+ ++
Sbjct: 560 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 619
Query: 155 DGRTCLGLKLGWGVS-C--QACPAQGSELYAVLCPEGPSKDNGGA-DINECTAVPGACPH 210
GR C + S C + C V C EG NG D++EC P C +
Sbjct: 620 RGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PNVCAN 677
Query: 211 GSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT 269
G C NLE Y C C GY D CRDIDEC + C GQC+NT GSF C C +G
Sbjct: 678 GDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGY 736
Query: 270 RHEPELQLCRDIDECE-------GE---TETHY---IESDYER---GDIPPTFPTRTELA 313
+ C DIDEC+ G+ TE + + Y GD E
Sbjct: 737 QLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDK 796
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLD----NRRGSCWRRVVDGQCEAAAPEL 369
S C G CINT G ++C C G+ LD + C D G C + G+C
Sbjct: 797 SVCQRGDCINTAGSYDCTCPDGFQLDDN-KTCQDINECEHPGLCGPQ---GECLNTEGSF 852
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + DG TC D+DEC + + G C N
Sbjct: 853 ----HCVCQQGFS-------------------ISADGRTCEDIDECVNNTVCDSHGFCDN 889
Query: 430 TDGSYRCDCPPGLTLDSTG 448
T GS+RC C G G
Sbjct: 890 TAGSFRCLCYQGFQAPQDG 908
Score = 188 bits (458), Expect = 4e-47
Identities = 121/379 (31%), Positives = 161/379 (42%), Gaps = 60/379 (15%)
Query: 79 DVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGRCH 136
+++EC + +C G C+N + C+C GYR + + CVD+DEC + Q +C GRC
Sbjct: 500 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 559
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQA-CPAQGSELYAVLCPEGPSKDN 193
NT GSF C C GF S +G C+ + L V + C C G
Sbjct: 560 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 619
Query: 194 GGA--DINECTAVPGACPHGSCENLEPGYRCI-CDPGYHPDADGLCRDIDECDMHQSYCA 250
G DI+EC P CP C N Y+C+ C G+ +G C D+DEC + + CA
Sbjct: 620 RGRCEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQCLDVDEC-LEPNVCA 676
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G C N GS+ C C +G P+ + CRDIDEC+ +G++
Sbjct: 677 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ-------------QGNL-------- 715
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELL 370
C NG+C NT G F C C GY L A +C D GQC
Sbjct: 716 -----CVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSF- 769
Query: 371 LRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNT 430
+C C G G G C D++EC +C G C+NT
Sbjct: 770 ---QCVCDQGYR---------------ASGL----GDHCEDINECLEDKSVCQRGDCINT 807
Query: 431 DGSYRCDCPPGLTLDSTGT 449
GSY C CP G LD T
Sbjct: 808 AGSYDCTCPDGFQLDDNKT 826
Score = 161 bits (390), Expect = 6e-39
Identities = 103/290 (35%), Positives = 138/290 (47%), Gaps = 35/290 (12%)
Query: 5 GMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G+C G C N +G F C+C+ G+ ++G C D+DEC +N G C NTAGS+ C
Sbjct: 837 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRC 896
Query: 64 LCEPGF-APTAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVC-EAGYRPTATRGAC-- 118
LC GF AP C DV+EC S +C C N EGSF CVC + + G C
Sbjct: 897 LCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRS 956
Query: 119 -------VDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC 170
VDVD+ EE++ C +N + C+ + ++ C GWG +C
Sbjct: 957 RTSTDLDVDVDQPKEEKKECY----YNLNDASLCDNVLAPNVTKQ-ECCCTSGAGWGDNC 1011
Query: 171 QA--CPAQGSELYAVLCPEGP--------SKDNGGA---DINECTAV-PGACPHGSCENL 216
+ CP G+ + +CP+G S + GG D +EC C +G C N
Sbjct: 1012 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT 1071
Query: 217 EPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
PGY C C G + D L C D+DEC S C GQC NT GS+ C C
Sbjct: 1072 RPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFC 1120
Score = 95.5 bits (227), Expect = 3e-19
Identities = 89/327 (27%), Positives = 129/327 (39%), Gaps = 52/327 (15%)
Query: 25 PGYESGSE--GALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADV 80
P ES SE G +D DEC +C+ G C NT Y C C+ G + C D+
Sbjct: 1036 PAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDM 1095
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV----DVDECEEQRVCRNGRCH 136
DEC S C G+CVN+EGS+ C C A+ C+ ++ EE V ++
Sbjct: 1096 DECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWE 1155
Query: 137 NTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC--PEGPSKDN 193
+ + C L G + CL + WG+ C CP + S+ YA LC P +
Sbjct: 1156 HLSDEYVCSRPLVGKQTTYTECCCLYGE-AWGMQCALCPLKDSDDYAQLCNIPVTGRRQP 1214
Query: 194 GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDI--DECDMHQSYCA 250
G D + + Y DP + D ++ +EC + C
Sbjct: 1215 YGRD--------------ALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CE 1259
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
G+C +TC C +G + C D++EC+ R
Sbjct: 1260 NGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECD-------------------ELNNRM 1300
Query: 311 ELASPCDNGRCINTHGGFECECELGYV 337
L C N +CINT G ++C C GYV
Sbjct: 1301 SL---CKNAKCINTDGSYKCLCLPGYV 1324
Score = 77.0 bits (181), Expect = 1e-13
Identities = 33/86 (38%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE----QRVCRNGRCH 136
+EC + C+ GRCV + + C C GY + CVDV+EC+E +C+N +C
Sbjct: 1250 EECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI 1309
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGL 162
NT GS++C CLPG+ S+ C L
Sbjct: 1310 NTDGSYKCLCLPGYVPSDKPNYCTPL 1335
Score = 71.3 bits (167), Expect = 6e-12
Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV-DVDE 123
C PG+ +C D++EC +C G C+N+ GS++C C+ G+ P T +CV D
Sbjct: 292 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 351
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTCLGLKLGWGVSCQACPAQGS 178
E++ G C+ S R +C+ ++ C + WG C+ CP G+
Sbjct: 352 ISEEK----GPCYRLVSSGR-QCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGT 402
Score = 69.3 bits (162), Expect = 3e-11
Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 11/163 (6%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAG 59
+ + +C N + N+ EC C G G + V + +C +G+ AG
Sbjct: 980 LNDASLCDNVLAPNVTKQ-ECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAG 1038
Query: 60 SYTCLCEPGFAPTAAGYCADVDECA--ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ E G Y D DEC +CK G C+N+ ++C C+ G +
Sbjct: 1039 ESSS--EAG----GENY-KDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQ 1091
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
C D+DEC++ C +G+C NT GS+ C C L + C+
Sbjct: 1092 CFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI 1134
Score = 68.1 bits (159), Expect = 6e-11
Identities = 32/81 (39%), Positives = 42/81 (51%), Gaps = 7/81 (8%)
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRC------LDNRRGSCWRRVVDG-QCE 363
+L C NG C+NT G + C C++G+ D T C + +G C+R V G QC
Sbjct: 311 QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCM 370
Query: 364 AAAPELLLRQECCCSVGLAWG 384
L +Q CCCSVG AWG
Sbjct: 371 HPLSVHLTKQLCCCSVGKAWG 391
Score = 67.7 bits (158), Expect = 8e-11
Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 4/79 (5%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRV--CRRGRCRNTAGSYTC 63
C NG C + G+ C C GY + C DV+EC + N R+ C+ +C NT GSY C
Sbjct: 1258 CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKC 1317
Query: 64 LCEPGFAPT-AAGYCADVD 81
LC PG+ P+ YC ++
Sbjct: 1318 LCLPGYVPSDKPNYCTPLN 1336
Score = 67.3 bits (157), Expect = 1e-10
Identities = 33/106 (31%), Positives = 50/106 (47%), Gaps = 10/106 (9%)
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG---------SXXXXXXXXXXXXXKGF 401
G C++ + QC A P L +++CC +VG +WG G+
Sbjct: 237 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY 296
Query: 402 AKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
+++ C+D++EC L +C G C+NT GSYRC C G D T
Sbjct: 297 KRVNNTFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPT 341
Score = 63.7 bits (148), Expect = 1e-09
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Query: 49 CRRGRCRNTAGSYTCLCEPGF-APTAAGYCADVDECAA----DSMCKGGRCVNSEGSFQC 103
C GRC YTC C G+ TA C DV+EC S+CK +C+N++GS++C
Sbjct: 1258 CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKC 1317
Query: 104 VCEAGYRPTATRGACVDVD 122
+C GY P+ C ++
Sbjct: 1318 LCLPGYVPSDKPNYCTPLN 1336
Score = 57.2 bits (132), Expect = 1e-07
Identities = 40/106 (37%), Positives = 50/106 (47%), Gaps = 10/106 (9%)
Query: 133 GRC-HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQACPAQGS-ELYAVL--CPE 187
GRC T GS + LPG + D C + WG + CQ CP + S Y + C
Sbjct: 237 GRCFQETIGSQCGKALPGLSKQED--CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 294
Query: 188 GPSKDNGG--ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
G + N DINEC + G CP+G C N YRC C G+ PD
Sbjct: 295 GYKRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPD 339
Score = 52.4 bits (120), Expect = 3e-06
Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
C PGY + C+DI+EC + Q C G+C NT GS+ C C G +P C
Sbjct: 292 CLPGYKRVNNTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 345
Score = 50.8 bits (116), Expect = 1e-05
Identities = 22/49 (44%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C PGY+ + C+D++EC+ VC G C NT GSY C C+ GF P
Sbjct: 292 CLPGYKRVNN-TFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGP 338
Score = 48.4 bits (110), Expect = 5e-05
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 14/85 (16%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCL------------DNRRGSCWRRVVDGQ 361
S C +G+C+NT G + C C VLDA+ +RC+ D + CW + D
Sbjct: 1102 SSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEY 1161
Query: 362 -C-EAAAPELLLRQECCCSVGLAWG 384
C + ECCC G AWG
Sbjct: 1162 VCSRPLVGKQTTYTECCCLYGEAWG 1186
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/37 (54%), Positives = 24/37 (64%), Gaps = 3/37 (8%)
Query: 408 TCRDVDEC-ALS--AELCAGGTCVNTDGSYRCDCPPG 441
TC DV+EC L+ LC C+NTDGSY+C C PG
Sbjct: 1286 TCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1322
Score = 41.5 bits (93), Expect = 0.006
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLD 347
C+NGRC+ G+ C+C GY LD C+D
Sbjct: 1258 CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVD 1289
Score = 36.7 bits (81), Expect = 0.17
Identities = 16/48 (33%), Positives = 24/48 (50%), Gaps = 4/48 (8%)
Query: 197 DINECTAVPGA---CPHGSCENLEPGYRCICDPGYHP-DADGLCRDID 240
D+NEC + C + C N + Y+C+C PGY P D C ++
Sbjct: 1289 DVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1336
Score = 36.3 bits (80), Expect = 0.22
Identities = 12/31 (38%), Positives = 17/31 (54%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALC 36
+C N C N DG ++C+C PGY + C
Sbjct: 1302 LCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1332
Score = 32.3 bits (70), Expect = 3.6
Identities = 11/23 (47%), Positives = 14/23 (60%)
Query: 5 GMCTNGICKNIDGGFECICKPGY 27
G+C NG C N G + C CK G+
Sbjct: 314 GVCPNGECLNTMGSYRCTCKIGF 336
>X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein.
Length = 754
Score = 237 bits (579), Expect = 8e-62
Identities = 130/366 (35%), Positives = 182/366 (49%), Gaps = 35/366 (9%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
GMCT G C+N G F+C C G+ E C D+DECR +P +C G C NT GS+ C
Sbjct: 330 GMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECE 389
Query: 65 CEPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C G+ C D+D C + +C+GG CVN+EGSFQC C G+ + +R CVD+
Sbjct: 390 CFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDI 449
Query: 122 DECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQ 176
+EC +CRNG+C N G+++C C PG+ + D + C + + G Q ++
Sbjct: 450 NECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSE 509
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
GS Y C EG + G ADI+EC P C G C N+ YRC+C G+ D
Sbjct: 510 GS--YECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMD 567
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C D++ECD++ + C G+C NT GSF C C G + C D+DEC E H
Sbjct: 568 MKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDEC--EIGAHN 625
Query: 293 IESDYERGDIPPTFP---------------TRTELAS---PCD-NGRCINTHGGFECECE 333
+ +IP +F R E ++ C N +C+NT G + C C
Sbjct: 626 CDMHASCLNIPGSFKCSCREGWIGNGIKCIDRDECSNGTHQCSINAQCVNTPGSYRCACS 685
Query: 334 LGYVLD 339
G+ D
Sbjct: 686 EGFTGD 691
Score = 224 bits (547), Expect = 6e-58
Identities = 147/450 (32%), Positives = 198/450 (44%), Gaps = 53/450 (11%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NGIC+N+ G + C C GYE + G C D+DEC N +C G CRNT GSY+C C
Sbjct: 26 ICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTC 85
Query: 66 EPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
PG+ T C D++EC ++ C G C N+ GSF C C G + ++T C+D
Sbjct: 86 PPGYVFRTETETCEDINECESNP-CVNGACRNNLGSFNCECSPGSKLSSTGLICID---- 140
Query: 125 EEQRVCRNGRCHNTPGSFRCEC-LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAV 183
G C RCE + G TL ++ C L WG C+ C EL
Sbjct: 141 -----SLKGTCWLNIQDSRCEVNINGATLKSE--CCATLGAAWGSPCERC-----EL-DT 187
Query: 184 LCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDID 240
CP G ++ G D+NEC PG CP+G C N + + C C G D G +C DI
Sbjct: 188 ACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIR 247
Query: 241 ECDMHQSYCAGGQCRNTAGSF---TCVCPEGTRHEPELQLCRDIDECEGETETHYIESDY 297
+ + G F C C G E + C E ET
Sbjct: 248 MEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFA 307
Query: 298 ERGDIPPTFPTRTEL----ASP--CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRG 351
RGD+ P ++ A P C G+C NT G F+C C G+ LD + C D
Sbjct: 308 NRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD---- 363
Query: 352 SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRD 411
+D +C +P+L C G+ + GF + C D
Sbjct: 364 ------ID-ECR-ISPDL-------CGSGICVNTPGSFECECFEGYESGFMMM--KNCMD 406
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+D C + LC GGTCVNT+GS++CDCP G
Sbjct: 407 IDGCERNPLLCRGGTCVNTEGSFQCDCPLG 436
Score = 213 bits (519), Expect = 1e-54
Identities = 127/372 (34%), Positives = 173/372 (46%), Gaps = 39/372 (10%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGAL-CRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
+C +GIC N G FEC C GYESG C D+D C NP +CR G C NT GS+ C
Sbjct: 373 LCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCD 432
Query: 65 CEPG--FAPTAAGYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C G +P+ C D++EC+ +D++C+ G+CVN G++QC C GY+ T R C D+
Sbjct: 433 CPLGHELSPSRED-CVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDI 491
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK-------LGWGVSCQACP 174
DEC + +C N+ GS+ C C G+ L DGR+C + + G C P
Sbjct: 492 DECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIP 551
Query: 175 AQGSELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
+ Y LC +G S D D+NEC C G CEN + + C C GY
Sbjct: 552 GE----YRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVK 607
Query: 232 ADGL-CRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE 289
C D+DEC++ C C N GSF C C EG C D DEC T
Sbjct: 608 KGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIK--CIDRDECSNGTH 665
Query: 290 THYIESDY-----------ERGDIPPTFPTR-----TELASPCDNGRCINTHGGFECECE 333
I + G F E + C+NG+C+N G + CECE
Sbjct: 666 QCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECE 725
Query: 334 LGYVLDATAQRC 345
+G+ + ++ C
Sbjct: 726 MGFTPASDSRSC 737
Score = 208 bits (508), Expect = 3e-53
Identities = 105/266 (39%), Positives = 134/266 (50%), Gaps = 29/266 (10%)
Query: 184 LCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDEC 242
LC G G DINEC P C +G CENL YRC C+ GY PDA G C DIDEC
Sbjct: 3 LCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDEC 62
Query: 243 DMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI 302
+++ C G CRNT GS++C CP G E + CE E
Sbjct: 63 LVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETET------CEDINECE----------- 105
Query: 303 PPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQC 362
++PC NG C N G F CEC G L +T C+D+ +G+CW + D +C
Sbjct: 106 ----------SNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRC 155
Query: 363 EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELC 422
E L+ ECC ++G AWGS +G A++ G TC DV+EC + +C
Sbjct: 156 EVNINGATLKSECCATLGAAWGS-PCERCELDTACPRGLARIKGVTCEDVNECEVFPGVC 214
Query: 423 AGGTCVNTDGSYRCDCPPGLTLDSTG 448
G CVN+ GS+ C+CP GLTLD TG
Sbjct: 215 PNGRCVNSKGSFHCECPEGLTLDGTG 240
Score = 207 bits (505), Expect = 7e-53
Identities = 140/422 (33%), Positives = 185/422 (43%), Gaps = 63/422 (14%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDECA-ADSMCKGGRC 94
+D++EC+ P +C G+CRNT GS+ C C GFA C D+DEC + +C G C
Sbjct: 320 KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGIC 379
Query: 95 VNSEGSFQCVCEAGYRPT-ATRGACVDVDECEEQRV-CRNGRCHNTPGSFRCECLPGFTL 152
VN+ GSF+C C GY C+D+D CE + CR G C NT GSF+C+C G L
Sbjct: 380 VNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHEL 439
Query: 153 SNDGRTCLGLKLGWGVSCQACP----AQGSELYAVLCPEG--PSKDNGGA-DINECTAVP 205
S C+ + +S C Y C G + D G DI+EC +
Sbjct: 440 SPSREDCVDIN-ECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMN 498
Query: 206 GACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCV 264
G C C N E Y C C GY DG C DIDEC+ + C GGQC N G + C+
Sbjct: 499 GGCDT-QCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCL 557
Query: 265 CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT 324
C +G +++ C D++EC+ + S+ C G C NT
Sbjct: 558 CYDGFMASMDMKTCIDVNECD-------LNSNI------------------CMFGECENT 592
Query: 325 HGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG 384
G F C C+LGY + C D VD +CE A + C G
Sbjct: 593 KGSFICHCQLGYSVKKGTTGCTD----------VD-ECEIGAHNCDMHASCLNIPG---- 637
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLT 443
+G+ +G C D DEC+ C+ CVNT GSYRC C G T
Sbjct: 638 -------SFKCSCREGWIG-NGIKCIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGFT 689
Query: 444 LD 445
D
Sbjct: 690 GD 691
Score = 203 bits (496), Expect = 9e-52
Identities = 162/509 (31%), Positives = 211/509 (41%), Gaps = 78/509 (15%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGS 60
+ N +C NG+C+N G + C C PGY +E C D++EC NP C G CRN GS
Sbjct: 63 LVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNP--CVNGACRNNLGS 120
Query: 61 YTCLCEPGFAPTAAG-YCAD--VDEC---AADSMCK---GGRCVNSE------GSFQCVC 105
+ C C PG ++ G C D C DS C+ G + SE ++ C
Sbjct: 121 FNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPC 180
Query: 106 EAGYRPTA-TRG-------ACVDVDECEE-QRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
E TA RG C DV+ECE VC NGRC N+ GSF CEC G TL G
Sbjct: 181 ERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTG 240
Query: 157 RTCLGLK-----LGWGVSCQACPAQGS-ELYAVLCPEGPSKDNGGADINECTAVPGACPH 210
R CL ++ L W P G + A C G + G + EC PG +
Sbjct: 241 RVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAA---WGTECEECPK-PGTKEY 296
Query: 211 GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR 270
E L P + G +DI+EC C G+CRNT GSF C C G
Sbjct: 297 ---ETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFA 353
Query: 271 HEPELQLCRDIDECE---------------GETETHYIESDYERGDIPPTFPTRTE--LA 313
+ E + C DIDEC G E E YE G + +
Sbjct: 354 LDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEG-YESGFMMMKNCMDIDGCER 412
Query: 314 SP--CDNGRCINTHGGFECECELGYVLDATAQRCLD----------NRRGSCWRRVVDGQ 361
+P C G C+NT G F+C+C LG+ L + + C+D R G C + Q
Sbjct: 413 NPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQ 472
Query: 362 CEA-----AAPE---LLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL-DGATCRDV 412
C A P+ EC G +G+A + DG +C D+
Sbjct: 473 CSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADI 532
Query: 413 DECALSAELCAGGTCVNTDGSYRCDCPPG 441
DEC + ++C GG C N G YRC C G
Sbjct: 533 DECENNPDICDGGQCTNIPGEYRCLCYDG 561
Score = 195 bits (475), Expect = 3e-49
Identities = 162/526 (30%), Positives = 215/526 (40%), Gaps = 95/526 (18%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDV-----------DEC-RDNPRVCRRG 52
G+C NG C N G F C C G G +C D+ DEC P R
Sbjct: 212 GVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMD 271
Query: 53 RCRNTAGS----------------YTCLCE--PGFAP-----TAAGYCADVDECAA-DSM 88
C G+ Y LC GFA T + D++EC A M
Sbjct: 272 ACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGM 331
Query: 89 CKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECL 147
C G+C N+ GSF+C C +G+ C D+DEC +C +G C NTPGSF CEC
Sbjct: 332 CTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECF 391
Query: 148 PG----FTLSNDGRTCLGLKLGWGVSCQACPAQGSE-LYAVLCPEG----PSKDNGGADI 198
G F + + G + + C+ +E + CP G PS+++ DI
Sbjct: 392 EGYESGFMMMKNCMDIDGCERN-PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDC-VDI 449
Query: 199 NECTAVPGACPHGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYCAGGQCRN 256
NEC+ C +G C N+ Y+C C+PGY PD G C DIDEC + C QC N
Sbjct: 450 NECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQG-CTDIDECMIMNGGC-DTQCTN 507
Query: 257 TAGSFTCVCPEGTRHEPELQLCRDIDECEGET------ETHYIESDYE---RGDIPPTFP 307
+ GS+ C C EG P+ + C DIDECE + I +Y +
Sbjct: 508 SEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMD 567
Query: 308 TRTEL-ASPCD-------NGRCINTHGGFECECELGYVLDATAQRCLD-----------N 348
+T + + CD G C NT G F C C+LGY + C D +
Sbjct: 568 MKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCD 627
Query: 349 RRGSCWRRVVDGQCEAA------APELLLRQECC-----CSVGLAWGSXXXXXXXXXXXX 397
SC +C + + R EC CS+
Sbjct: 628 MHASCLNIPGSFKCSCREGWIGNGIKCIDRDECSNGTHQCSIN---AQCVNTPGSYRCAC 684
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+GF DG TC DVDECA + LC G C+N G+YRC+C G T
Sbjct: 685 SEGFTG-DGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFT 729
Score = 194 bits (472), Expect = 7e-49
Identities = 152/510 (29%), Positives = 202/510 (39%), Gaps = 84/510 (16%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDV-----------DECRDNPR-VCRRGRC 54
C NG C+N G F C C PG + S G +C D C N + C
Sbjct: 109 CVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSEC 168
Query: 55 RNTAGSY------TC----LCEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQC 103
T G+ C C G A C DV+EC +C GRCVNS+GSF C
Sbjct: 169 CATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHC 228
Query: 104 VCEAGYRPTATRGACVDVDECEEQRVCRNGRC-HNTPGSFRCECLPGFTLSNDGRTCLGL 162
C G T C+D+ + C H PG FR + C +
Sbjct: 229 ECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDAC-----------CCAV 277
Query: 163 KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---------ADINECTAVPGACPHGSC 213
WG C+ CP G++ Y LCP G N G DINEC A PG C +G C
Sbjct: 278 GAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKC 337
Query: 214 ENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE 272
N ++C C+ G+ D + C DIDEC + C G C NT GSF C C EG
Sbjct: 338 RNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESG 397
Query: 273 -PELQLCRDIDECEGE-----------TETHYIESDYERG-DIPPTFPTRTELA------ 313
++ C DID CE TE + + D G ++ P+ ++
Sbjct: 398 FMMMKNCMDIDGCERNPLLCRGGTCVNTEGSF-QCDCPLGHELSPSREDCVDINECSLSD 456
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDN-----RRGSCWRRVV--DGQCEAAA 366
+ C NG+C+N G ++C C GY Q C D G C + +G E +
Sbjct: 457 NLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSC 516
Query: 367 PE---LLLRQECCCSVGLA--------WGSXXXXXXXXXXXXXKGF-AKLDGATCRDVDE 414
E L+ C + G GF A +D TC DV+E
Sbjct: 517 SEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNE 576
Query: 415 CALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
C L++ +C G C NT GS+ C C G ++
Sbjct: 577 CDLNSNICMFGECENTKGSFICHCQLGYSV 606
Score = 175 bits (427), Expect = 2e-43
Identities = 94/285 (32%), Positives = 136/285 (47%), Gaps = 15/285 (5%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C N+ G ++C C PGY++ + C D+DEC C +C N+ GSY C C
Sbjct: 458 LCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDT-QCTNSEGSYECSC 516
Query: 66 EPGFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
G+A G CAD+DEC + +C GG+C N G ++C+C G+ + C+DV+E
Sbjct: 517 SEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNE 576
Query: 124 CE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL-- 180
C+ +C G C NT GSF C C G+++ C + + C S L
Sbjct: 577 CDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVD-ECEIGAHNCDMHASCLNI 635
Query: 181 ---YAVLCPEGPSKDNG--GADINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADG 234
+ C EG NG D +EC+ C + C N YRC C G+ D
Sbjct: 636 PGSFKCSCREGWI-GNGIKCIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGF- 693
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR 279
C D+DEC + + C GQC N G++ C C G + + C+
Sbjct: 694 TCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQ 738
Score = 131 bits (316), Expect = 6e-30
Identities = 65/163 (39%), Positives = 84/163 (51%), Gaps = 7/163 (4%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCRNTAGSY 61
N +C G C+N G F C C+ GY C DVDEC C C N GS+
Sbjct: 580 NSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSF 639
Query: 62 TCLCEPGFAPTAAGYCADVDECAADS-MCK-GGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C G+ C D DEC+ + C +CVN+ GS++C C G+ T C
Sbjct: 640 KCSCREGWIGNGIK-CIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGF--TGDGFTCS 696
Query: 120 DVDECEEQ-RVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLG 161
DVDEC E +C NG+C N PG++RCEC GFT ++D R+C G
Sbjct: 697 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQG 739
Score = 127 bits (307), Expect = 7e-29
Identities = 63/162 (38%), Positives = 84/162 (51%), Gaps = 9/162 (5%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C NI G + C+C G+ + + C DV+EC N +C G C NT GS+
Sbjct: 538 NPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFI 597
Query: 63 CLCEPGFA-PTAAGYCADVDEC--AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C+ G++ C DVDEC A + C+N GSF+C C G+ + C+
Sbjct: 598 CHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIK--CI 655
Query: 120 DVDECEE--QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
D DEC + N +C NTPGS+RC C GFT DG TC
Sbjct: 656 DRDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTC 695
>BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein.
Length = 743
Score = 237 bits (579), Expect = 8e-62
Identities = 155/476 (32%), Positives = 211/476 (44%), Gaps = 61/476 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C +G C + C C PGY S + C DV+EC P RG C NT GSY
Sbjct: 68 NQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYN 127
Query: 63 CLCEPGF-APTAAG--YCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATR-GA 117
C C G+ AG C D++ECA +C GG C+N G ++C C GYR A+R
Sbjct: 128 CHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPV 187
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRC-ECLPGFTLSNDGRTCLGL-KLGWGVSCQACPA 175
C D+DEC + C +G+C N PGSF+C C PG+ S G C + + G C
Sbjct: 188 CEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYR-SQGGGACRDVNECAEGSPCSPGWC 246
Query: 176 QG-SELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
+ + C +G P+ D D++EC A C +G C N ++C C GYH
Sbjct: 247 ENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA-GDVCDNGICSNTPGSFQCQCLSGYHLS 305
Query: 232 AD-GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
D C DIDECD + C GG C NT GS+ C+CP+G R + C+DIDEC +
Sbjct: 306 RDRSHCEDIDECDF-PAACIGGDCINTNGSYRCLCPQGHRLVGG-RKCQDIDECSQD--- 360
Query: 291 HYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD--- 347
L P +G C N G + C C+ G+ C +
Sbjct: 361 -------------------PSLCLP--HGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQ 399
Query: 348 -NRRGSCWRRVVDGQ-CEAAAPELLLRQECCCSVGLAWGS---------XXXXXXXXXXX 396
+ + C+ D C++ + +QECCCS+G WG
Sbjct: 400 PHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCP 459
Query: 397 XXKGFAKLDG------ATCRDVDECAL-SAELCAGGTCVNTDGSYRCDCPPGLTLD 445
KG+ + + RD+DEC L +E+C G CVNT Y C C G D
Sbjct: 460 DGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYD 515
Score = 199 bits (485), Expect = 2e-50
Identities = 106/302 (35%), Positives = 146/302 (48%), Gaps = 23/302 (7%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C NGIC N G F+C C GY + + C D+DEC D P C G C NT GSY C
Sbjct: 279 GDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINTNGSYRC 337
Query: 64 LCEPGFAPTAAGYCADVDECAAD-SMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
LC G C D+DEC+ D S+C G C N +GS+ CVC+ G+ PT + C +V
Sbjct: 338 LCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEV 397
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQA--CPAQGSE 179
++ ++ C N + C+ + ++ C L GWG C+ CP S
Sbjct: 398 EQPHHKKECYL----NFDDTVFCDSVLATNVTQQ-ECCCSLGAGWGDHCEIYPCPVYSSA 452
Query: 180 LYAVLCPEGP--SKDNG--------GADINECTAVPGA-CPHGSCENLEPGYRCICDPGY 228
+ LCP+G ++DN DI+EC C G C N +PGY C C G+
Sbjct: 453 EFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGF 512
Query: 229 HPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE 287
+ D + L C D+DEC + +S C G C NT G + C C + P + C +E E
Sbjct: 513 YYDGNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERA 571
Query: 288 TE 289
E
Sbjct: 572 PE 573
Score = 190 bits (464), Expect = 7e-48
Identities = 147/484 (30%), Positives = 193/484 (39%), Gaps = 73/484 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C+ G C+N+ G F C C GY +G C DVDEC VC G C NT GS+ C
Sbjct: 238 GSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGD-VCDNGICSNTPGSFQC 296
Query: 64 LCEPGFAPTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C G+ + +C D+DEC + C GG C+N+ GS++C+C G+R R C D+D
Sbjct: 297 QCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGR-KCQDID 355
Query: 123 EC-EEQRVCR-NGRCHNTPGSFRCECLPGFTLSNDGRTC-----------LGLKLGWGVS 169
EC ++ +C +G C N GS+ C C GFT + D C L V
Sbjct: 356 ECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVF 415
Query: 170 CQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
C + A C G + +I C A H C + + GY D
Sbjct: 416 CDSVLATNVTQQECCCSLGAGWGDH-CEIYPCPVYSSAEFHSLCPDGK-GYTQ--DNNIV 471
Query: 230 PDADGLCRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET 288
RDIDEC + S C G+C NT + C C +G ++ L C D+DEC E
Sbjct: 472 NYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDE- 530
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD- 347
S C NG C NT GG+ C C ++CL
Sbjct: 531 -------------------------SNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSP 565
Query: 348 -------NRRGSCW-RRVVDGQCEA--AAPELLLRQECCCSVGLAWGS--------XXXX 389
RR CW +R DG C A P L +CCC G WG+
Sbjct: 566 EEMERAPERRDVCWSQRGEDGMCAGPLAGPALTF-DDCCCRQGRGWGAQCRPCPPRGAGS 624
Query: 390 XXXXXXXXXKGF----AKLDGATCRDVDECALSAE--LCAGGTCVNTDGSYRCDCPPGLT 443
F L G RD D ++ C G CV G C+CP G
Sbjct: 625 HCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQ 684
Query: 444 LDST 447
LD++
Sbjct: 685 LDAS 688
Score = 171 bits (415), Expect = 6e-42
Identities = 126/383 (32%), Positives = 163/383 (42%), Gaps = 75/383 (19%)
Query: 79 DVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR--C 135
+ DEC + ++C G CV + C C GYR CVDV+ECE + C GR C
Sbjct: 61 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP-CGPGRGIC 119
Query: 136 HNTPGSFRCECLPGFTL--SNDGRTCLGLK-------LGWGVSCQACPAQGSELYAVLCP 186
NT GS+ C C G+ L GR+C+ L G G C P Y C
Sbjct: 120 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGH----YKCNCY 175
Query: 187 EG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCI-CDPGYHPDADGLCRDIDE 241
G S+ DI+EC P +CP G CEN ++CI C PGY G CRD++E
Sbjct: 176 PGYRLKASRPPVCEDIDECRD-PSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNE 234
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGD 301
C S C+ G C N GSF C C +G P+ + C D+DECE GD
Sbjct: 235 C-AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA-------------GD 280
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQ 361
+ CDNG C NT G F+C+C GY L C D +D +
Sbjct: 281 V-------------CDNGICSNTPGSFQCQCLSGYHLSRDRSHCED----------ID-E 316
Query: 362 CEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAEL 421
C+ P + +C + G +G + G C+D+DEC+ L
Sbjct: 317 CD--FPAACIGGDCINTNG-----------SYRCLCPQGHRLVGGRKCQDIDECSQDPSL 363
Query: 422 C-AGGTCVNTDGSYRCDCPPGLT 443
C G C N GSY C C G T
Sbjct: 364 CLPHGACKNLQGSYVCVCDEGFT 386
Score = 116 bits (279), Expect = 2e-25
Identities = 80/254 (31%), Positives = 109/254 (42%), Gaps = 27/254 (10%)
Query: 37 RDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRC 94
RD+DEC +C+ G+C NT Y C C+ GF C DVDEC +S C+ G C
Sbjct: 479 RDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVC 538
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG--SFRCECLPGFTL 152
N+ G ++C C + + C+ +E E R C + G L G L
Sbjct: 539 ENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPE-RRDVCWSQRGEDGMCAGPLAGPAL 597
Query: 153 SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNG--------------GADI 198
+ D C GWG C+ CP +G+ + CP S+ N D
Sbjct: 598 TFDD-CCCRQGRGWGAQCRPCPPRGAGSH---CPTSQSESNSFWDTSPLLLGKPPRDEDS 653
Query: 199 NECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDEC-DMHQS--YCAGGQC 254
+E + C G C G C C G+ DA C DIDEC +++Q C +C
Sbjct: 654 SEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERC 713
Query: 255 RNTAGSFTCVCPEG 268
NT+GSF CVC G
Sbjct: 714 VNTSGSFRCVCKAG 727
Score = 104 bits (249), Expect = 7e-22
Identities = 97/380 (25%), Positives = 145/380 (38%), Gaps = 47/380 (12%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCLC 65
C G C N +G + C+C G+ G C+D+DEC +P +C G C+N GSY C+C
Sbjct: 323 CIGGDCINTNGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVC 381
Query: 66 EPGFAPTAAGY-CADVD------ECAA---DSMCKGGRCVNSEGSFQCVCE--AGYRPTA 113
+ GF PT + C +V+ EC D++ + +C C AG+
Sbjct: 382 DEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHC 441
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQAC 173
C E +C +G+ + + +P D C+ G + +
Sbjct: 442 EIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAH---RDIDECM--LFGSEICKEGK 496
Query: 174 PAQGSELYAVLCPEGPSKDNG---GADINECTAVPGACPHGSCENLEPGYRCICDPG--Y 228
Y C +G D D++EC C +G CEN GYRC C P Y
Sbjct: 497 CVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESN-CRNGVCENTRGGYRCACTPPAEY 555
Query: 229 HPDADGLCRDIDECDM-------------HQSYCAGGQCRNTAGSFTCVCPEGTRHEPEL 275
P A C +E + CAG C C +G +
Sbjct: 556 SP-AQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQC 614
Query: 276 QLCRDI---DEC---EGETETHYIESDYERGDIPPTFPTRTELASPCD--NGRCINTHGG 327
+ C C + E+ + + S G P + E + C +GRC+ GG
Sbjct: 615 RPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGG 674
Query: 328 FECECELGYVLDATAQRCLD 347
CEC G+ LDA+ RC+D
Sbjct: 675 AVCECPGGFQLDASRARCVD 694
Score = 77.0 bits (181), Expect = 1e-13
Identities = 39/86 (45%), Positives = 47/86 (54%), Gaps = 8/86 (9%)
Query: 79 DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE--QR--VCRNGR 134
D DEC C GRCV G C C G++ A+R CVD+DEC E QR +C++ R
Sbjct: 657 DSDECR----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSER 712
Query: 135 CHNTPGSFRCECLPGFTLSNDGRTCL 160
C NT GSFRC C GF S C+
Sbjct: 713 CVNTSGSFRCVCKAGFARSRPHGACV 738
Score = 72.5 bits (170), Expect = 3e-12
Identities = 38/87 (43%), Positives = 47/87 (54%), Gaps = 10/87 (11%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAA-GYCADVDECAADS----MCKGG 92
D DECR C GRC G C C GF A+ C D+DEC + +CK
Sbjct: 657 DSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSE 711
Query: 93 RCVNSEGSFQCVCEAGYRPTATRGACV 119
RCVN+ GSF+CVC+AG+ + GACV
Sbjct: 712 RCVNTSGSFRCVCKAGFARSRPHGACV 738
Score = 64.5 bits (150), Expect = 7e-10
Identities = 29/67 (43%), Positives = 41/67 (61%), Gaps = 3/67 (4%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPR--VCRRGRCRNTAGSYTC 63
C +G C GG C C G++ + A C D+DECR+ N R +C+ RC NT+GS+ C
Sbjct: 663 CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRC 722
Query: 64 LCEPGFA 70
+C+ GFA
Sbjct: 723 VCKAGFA 729
Score = 44.0 bits (99), Expect = 0.001
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDST 447
G +C D++ECA LC GG C+N G Y+C+C PG L ++
Sbjct: 142 GRSCVDLNECA-KPHLCGDGGFCINFPGHYKCNCYPGYRLKAS 183
Score = 39.1 bits (87), Expect = 0.032
Identities = 18/38 (47%), Positives = 21/38 (55%), Gaps = 3/38 (7%)
Query: 407 ATCRDVDECALSAE---LCAGGTCVNTDGSYRCDCPPG 441
A C D+DEC + LC CVNT GS+RC C G
Sbjct: 690 ARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG 727
Score = 31.5 bits (68), Expect = 6.3
Identities = 11/33 (33%), Positives = 15/33 (45%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALC 36
G +C + C N G F C+CK G+ C
Sbjct: 705 GLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 737
>AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.
Length = 1382
Score = 237 bits (579), Expect = 8e-62
Identities = 155/476 (32%), Positives = 211/476 (44%), Gaps = 61/476 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C +G C + C C PGY S + C DV+EC P RG C NT GSY
Sbjct: 660 NQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYN 719
Query: 63 CLCEPGF-APTAAG--YCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATR-GA 117
C C G+ AG C D++ECA +C GG C+N G ++C C GYR A+R
Sbjct: 720 CHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPV 779
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRC-ECLPGFTLSNDGRTCLGL-KLGWGVSCQACPA 175
C D+DEC + C +G+C N PGSF+C C PG+ S G C + + G C
Sbjct: 780 CEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYR-SQGGGACRDVNECAEGSPCSPGWC 838
Query: 176 QG-SELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
+ + C +G P+ D D++EC A C +G C N ++C C GYH
Sbjct: 839 ENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA-GDVCDNGICSNTPGSFQCQCLSGYHLS 897
Query: 232 AD-GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
D C DIDECD + C GG C NT GS+ C+CP+G R + C+DIDEC +
Sbjct: 898 RDRSHCEDIDECDF-PAACIGGDCINTNGSYRCLCPQGHRLVGG-RKCQDIDECSQD--- 952
Query: 291 HYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD--- 347
L P +G C N G + C C+ G+ C +
Sbjct: 953 -------------------PSLCLP--HGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQ 991
Query: 348 -NRRGSCWRRVVDGQ-CEAAAPELLLRQECCCSVGLAWGS---------XXXXXXXXXXX 396
+ + C+ D C++ + +QECCCS+G WG
Sbjct: 992 PHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCP 1051
Query: 397 XXKGFAKLDG------ATCRDVDECAL-SAELCAGGTCVNTDGSYRCDCPPGLTLD 445
KG+ + + RD+DEC L +E+C G CVNT Y C C G D
Sbjct: 1052 DGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYD 1107
Score = 228 bits (557), Expect = 4e-59
Identities = 151/486 (31%), Positives = 206/486 (42%), Gaps = 71/486 (14%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C NGIC N G F+C C GY + + C D+DEC D P C G C NT GSY C
Sbjct: 871 GDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINTNGSYRC 929
Query: 64 LCEPGFAPTAAGYCADVDECAAD-SMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
LC G C D+DEC+ D S+C G C N +GS+ CVC+ G+ PT + C +V
Sbjct: 930 LCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEV 989
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQA--CPAQGSE 179
++ ++ C N + C+ + ++ C L GWG C+ CP S
Sbjct: 990 EQPHHKKECYL----NFDDTVFCDSVLATNVTQQ-ECCCSLGAGWGDHCEIYPCPVYSSA 1044
Query: 180 LYAVLCPEGP--SKDN--------GGADINECTAVPG-ACPHGSCENLEPGYRCICDPGY 228
+ LCP+G ++DN DI+EC C G C N +PGY C C G+
Sbjct: 1045 EFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGF 1104
Query: 229 HPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE 287
+ D + L C D+DEC + +S C G C NT G + C C + P + C +
Sbjct: 1105 YYDGNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPE----- 1158
Query: 288 TETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC-- 345
E D + P + C GRC+N G + CEC +V + + C
Sbjct: 1159 ------EMDVDECQDP----------AACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQL 1202
Query: 346 -------LDNRRGSCW-RRVVDGQCEA--AAPELLLRQECCCSVGLAWGS--------XX 387
RR CW +R DG C A P L +CCC G WG+
Sbjct: 1203 PESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTF-DDCCCRQGRGWGAQCRPCPPRGA 1261
Query: 388 XXXXXXXXXXXKGF----AKLDGATCRDVDECALSAE--LCAGGTCVNTDGSYRCDCPPG 441
F L G RD D ++ C G CV G C+CP G
Sbjct: 1262 GSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGG 1321
Query: 442 LTLDST 447
LD++
Sbjct: 1322 FQLDAS 1327
Score = 171 bits (415), Expect = 6e-42
Identities = 126/383 (32%), Positives = 163/383 (42%), Gaps = 75/383 (19%)
Query: 79 DVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR--C 135
+ DEC + ++C G CV + C C GYR CVDV+ECE + C GR C
Sbjct: 653 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP-CGPGRGIC 711
Query: 136 HNTPGSFRCECLPGFTL--SNDGRTCLGLK-------LGWGVSCQACPAQGSELYAVLCP 186
NT GS+ C C G+ L GR+C+ L G G C P Y C
Sbjct: 712 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGH----YKCNCY 767
Query: 187 EG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCI-CDPGYHPDADGLCRDIDE 241
G S+ DI+EC P +CP G CEN ++CI C PGY G CRD++E
Sbjct: 768 PGYRLKASRPPVCEDIDECRD-PSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNE 826
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGD 301
C S C+ G C N GSF C C +G P+ + C D+DECE GD
Sbjct: 827 C-AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA-------------GD 872
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQ 361
+ CDNG C NT G F+C+C GY L C D +D +
Sbjct: 873 V-------------CDNGICSNTPGSFQCQCLSGYHLSRDRSHCED----------ID-E 908
Query: 362 CEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAEL 421
C+ P + +C + G +G + G C+D+DEC+ L
Sbjct: 909 CD--FPAACIGGDCINTNG-----------SYRCLCPQGHRLVGGRKCQDIDECSQDPSL 955
Query: 422 C-AGGTCVNTDGSYRCDCPPGLT 443
C G C N GSY C C G T
Sbjct: 956 CLPHGACKNLQGSYVCVCDEGFT 978
Score = 139 bits (337), Expect = 2e-32
Identities = 97/290 (33%), Positives = 125/290 (43%), Gaps = 33/290 (11%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C G C N G+EC CK G+ C DVDEC D CR G C NT G Y C C
Sbjct: 1083 ICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESN-CRNGVCENTRGGYRCAC 1141
Query: 66 EPG--FAPTAAGYCA-----DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC 118
P ++P A C DVDEC + C+ GRCVN GS++C C + P + C
Sbjct: 1142 TPPAEYSP-AQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDC 1200
Query: 119 VDVDECEEQRVCRNGRCHNTPG--SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ E+ R C + G L G L+ D C GWG C+ CP +
Sbjct: 1201 QLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDD-CCCRQGRGWGAQCRPCPPR 1259
Query: 177 GSELYAVLCPEGPSKDNG--------------GADINECTAVPGACPHGSCENLEPGYRC 222
G+ + CP S+ N D +E + C G C G C
Sbjct: 1260 GAGSH---CPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVC 1316
Query: 223 ICDPGYHPDAD-GLCRDIDEC-DMHQS--YCAGGQCRNTAGSFTCVCPEG 268
C G+ DA C DIDEC +++Q C +C NT+GSF CVC G
Sbjct: 1317 ECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG 1366
Score = 80.2 bits (189), Expect = 1e-14
Identities = 97/384 (25%), Positives = 143/384 (37%), Gaps = 54/384 (14%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVD------ECR---DNPRVCRRGRCRNTAG 59
+G CKN+ G + C+C G+ + C +V+ EC D+ C N
Sbjct: 959 HGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVT- 1017
Query: 60 SYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGAC 118
C C G G ++ C S + C + +G Q Y A R
Sbjct: 1018 QQECCCSLG---AGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHR--- 1071
Query: 119 VDVDECE--EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQ--AC 173
D+DEC +C+ G+C NT + C C GF + C+ + S C+ C
Sbjct: 1072 -DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVC 1130
Query: 174 P-AQGSELYAVLCPE--GPSKDN----GGADINECTAVPGACPHGSCENLEPGYRCICDP 226
+G A P P++ D++EC P AC G C NL YRC C P
Sbjct: 1131 ENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQD-PAACRPGRCVNLPGSYRCECRP 1189
Query: 227 GYHPDADGL-C-------------RDIDECDMHQSYCAGGQCRNTAGSFT-CVCPEGTRH 271
+ P G C RD+ + G A +F C C +G
Sbjct: 1190 PWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGW 1249
Query: 272 EPELQLCRDI---DEC---EGETETHYIESDYERGDIPPTFPTRTELASPCD--NGRCIN 323
+ + C C + E+ + + S G P + E + C +GRC+
Sbjct: 1250 GAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVP 1309
Query: 324 THGGFECECELGYVLDATAQRCLD 347
GG CEC G+ LDA+ RC+D
Sbjct: 1310 RPGGAVCECPGGFQLDASRARCVD 1333
Score = 77.8 bits (183), Expect = 7e-14
Identities = 37/124 (29%), Positives = 60/124 (48%), Gaps = 6/124 (4%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ + +C D++ECA +C+ G C+N+ GS++CVC G+ +R C+ D+
Sbjct: 420 CPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI-ADKP 478
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
EE+ +C +C+ P T C + WG CQ CP G+ + +
Sbjct: 479 EEKSLC----FRLVSPEHQCQ-HPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEI 533
Query: 185 CPEG 188
CP G
Sbjct: 534 CPAG 537
Score = 77.0 bits (181), Expect = 1e-13
Identities = 39/86 (45%), Positives = 47/86 (54%), Gaps = 8/86 (9%)
Query: 79 DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE--QR--VCRNGR 134
D DEC C GRCV G C C G++ A+R CVD+DEC E QR +C++ R
Sbjct: 1296 DSDECR----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSER 1351
Query: 135 CHNTPGSFRCECLPGFTLSNDGRTCL 160
C NT GSFRC C GF S C+
Sbjct: 1352 CVNTSGSFRCVCKAGFARSRPHGACV 1377
Score = 72.5 bits (170), Expect = 3e-12
Identities = 38/87 (43%), Positives = 47/87 (54%), Gaps = 10/87 (11%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAA-GYCADVDECAADS----MCKGG 92
D DECR C GRC G C C GF A+ C D+DEC + +CK
Sbjct: 1296 DSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSE 1350
Query: 93 RCVNSEGSFQCVCEAGYRPTATRGACV 119
RCVN+ GSF+CVC+AG+ + GACV
Sbjct: 1351 RCVNTSGSFRCVCKAGFARSRPHGACV 1377
Score = 59.3 bits (137), Expect = 3e-08
Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 6/81 (7%)
Query: 311 ELASP--CDNGRCINTHGGFECECELGYVLDATAQRCLDNR---RGSCWRRVV-DGQCEA 364
E A P C +G C+N G + C C G+ L + +C+ ++ + C+R V + QC+
Sbjct: 437 ECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQH 496
Query: 365 AAPELLLRQECCCSVGLAWGS 385
L RQ CCCSVG AWG+
Sbjct: 497 PLTTRLTRQLCCCSVGKAWGA 517
Score = 58.4 bits (135), Expect = 5e-08
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 19/117 (16%)
Query: 351 GSCWRRVVDGQ-CEA-AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX---------- 398
G C++ + Q C + P L +++CC S+G AWG
Sbjct: 356 GRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGE 415
Query: 399 ------KGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+G+ +L+ C+D++ECA+ +C G C+N GSYRC CPPG +L + T
Sbjct: 416 VGADCPQGYKRLNSTHCQDINECAMPG-VCRHGDCLNNPGSYRCVCPPGHSLGPSRT 471
Score = 55.6 bits (128), Expect = 3e-07
Identities = 36/95 (37%), Positives = 44/95 (46%), Gaps = 16/95 (16%)
Query: 147 LPGFTLSNDGRTCLGLKLGWGVS-CQACPA---QGSELYAVL-------CPEGPSKDNGG 195
LPG T D C + WG S C CP G + + CP+G + N
Sbjct: 373 LPGLTKQED--CCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNST 430
Query: 196 --ADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
DINEC A+PG C HG C N YRC+C PG+
Sbjct: 431 HCQDINEC-AMPGVCRHGDCLNNPGSYRCVCPPGH 464
Score = 48.8 bits (111), Expect = 4e-05
Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 4/62 (6%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG--FAPTAAGYCADV 80
C GY+ C+D++EC P VCR G C N GSY C+C PG P+ AD
Sbjct: 420 CPQGYKR-LNSTHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADK 477
Query: 81 DE 82
E
Sbjct: 478 PE 479
Score = 46.0 bits (104), Expect = 3e-04
Identities = 22/55 (40%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
C GY C+DI+EC M C G C N GS+ CVCP G P C
Sbjct: 420 CPQGYKRLNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 473
Score = 44.0 bits (99), Expect = 0.001
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDST 447
G +C D++ECA LC GG C+N G Y+C+C PG L ++
Sbjct: 734 GRSCVDLNECA-KPHLCGDGGFCINFPGHYKCNCYPGYRLKAS 775
Score = 39.1 bits (87), Expect = 0.032
Identities = 18/38 (47%), Positives = 21/38 (55%), Gaps = 3/38 (7%)
Query: 407 ATCRDVDECALSAE---LCAGGTCVNTDGSYRCDCPPG 441
A C D+DEC + LC CVNT GS+RC C G
Sbjct: 1329 ARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG 1366
Score = 36.3 bits (80), Expect = 0.22
Identities = 12/32 (37%), Positives = 17/32 (53%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALC 36
G+C +G C N G + C+C PG+ G C
Sbjct: 442 GVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 473
Score = 31.5 bits (68), Expect = 6.3
Identities = 11/33 (33%), Positives = 15/33 (45%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALC 36
G +C + C N G F C+CK G+ C
Sbjct: 1344 GLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1376
>AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming growth
factor beta binding protein 3 protein.
Length = 1256
Score = 237 bits (579), Expect = 8e-62
Identities = 155/476 (32%), Positives = 211/476 (44%), Gaps = 61/476 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C +G C + C C PGY S + C DV+EC P RG C NT GSY
Sbjct: 581 NQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYN 640
Query: 63 CLCEPGF-APTAAG--YCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATR-GA 117
C C G+ AG C D++ECA +C GG C+N G ++C C GYR A+R
Sbjct: 641 CHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPV 700
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRC-ECLPGFTLSNDGRTCLGL-KLGWGVSCQACPA 175
C D+DEC + C +G+C N PGSF+C C PG+ S G C + + G C
Sbjct: 701 CEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYR-SQGGGACRDVNECAEGSPCSPGWC 759
Query: 176 QG-SELYAVLCPEG--PSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
+ + C +G P+ D D++EC A C +G C N ++C C GYH
Sbjct: 760 ENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA-GDVCDNGICSNTPGSFQCQCLSGYHLS 818
Query: 232 AD-GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
D C DIDECD + C GG C NT GS+ C+CP+G R + C+DIDEC +
Sbjct: 819 RDRSHCEDIDECDF-PAACIGGDCINTNGSYRCLCPQGHRLVGG-RKCQDIDECSQD--- 873
Query: 291 HYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD--- 347
L P +G C N G + C C+ G+ C +
Sbjct: 874 -------------------PSLCLP--HGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQ 912
Query: 348 -NRRGSCWRRVVDGQ-CEAAAPELLLRQECCCSVGLAWGS---------XXXXXXXXXXX 396
+ + C+ D C++ + +QECCCS+G WG
Sbjct: 913 PHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCP 972
Query: 397 XXKGFAKLDG------ATCRDVDECAL-SAELCAGGTCVNTDGSYRCDCPPGLTLD 445
KG+ + + RD+DEC L +E+C G CVNT Y C C G D
Sbjct: 973 DGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYD 1028
Score = 199 bits (485), Expect = 2e-50
Identities = 106/302 (35%), Positives = 146/302 (48%), Gaps = 23/302 (7%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C NGIC N G F+C C GY + + C D+DEC D P C G C NT GSY C
Sbjct: 792 GDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINTNGSYRC 850
Query: 64 LCEPGFAPTAAGYCADVDECAAD-SMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
LC G C D+DEC+ D S+C G C N +GS+ CVC+ G+ PT + C +V
Sbjct: 851 LCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEV 910
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQA--CPAQGSE 179
++ ++ C N + C+ + ++ C L GWG C+ CP S
Sbjct: 911 EQPHHKKECYL----NFDDTVFCDSVLATNVTQQ-ECCCSLGAGWGDHCEIYPCPVYSSA 965
Query: 180 LYAVLCPEGP--SKDNG--------GADINECTAVPGA-CPHGSCENLEPGYRCICDPGY 228
+ LCP+G ++DN DI+EC C G C N +PGY C C G+
Sbjct: 966 EFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGF 1025
Query: 229 HPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE 287
+ D + L C D+DEC + +S C G C NT G + C C + P + C +E E
Sbjct: 1026 YYDGNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERA 1084
Query: 288 TE 289
E
Sbjct: 1085 PE 1086
Score = 190 bits (464), Expect = 7e-48
Identities = 147/484 (30%), Positives = 193/484 (39%), Gaps = 73/484 (15%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C+ G C+N+ G F C C GY +G C DVDEC VC G C NT GS+ C
Sbjct: 751 GSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGD-VCDNGICSNTPGSFQC 809
Query: 64 LCEPGFAPTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C G+ + +C D+DEC + C GG C+N+ GS++C+C G+R R C D+D
Sbjct: 810 QCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGR-KCQDID 868
Query: 123 EC-EEQRVCR-NGRCHNTPGSFRCECLPGFTLSNDGRTC-----------LGLKLGWGVS 169
EC ++ +C +G C N GS+ C C GFT + D C L V
Sbjct: 869 ECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVF 928
Query: 170 CQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
C + A C G + +I C A H C + + GY D
Sbjct: 929 CDSVLATNVTQQECCCSLGAGWGDH-CEIYPCPVYSSAEFHSLCPDGK-GYTQ--DNNIV 984
Query: 230 PDADGLCRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET 288
RDIDEC + S C G+C NT + C C +G ++ L C D+DEC E
Sbjct: 985 NYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDE- 1043
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD- 347
S C NG C NT GG+ C C ++CL
Sbjct: 1044 -------------------------SNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSP 1078
Query: 348 -------NRRGSCW-RRVVDGQCEA--AAPELLLRQECCCSVGLAWGS--------XXXX 389
RR CW +R DG C A P L +CCC G WG+
Sbjct: 1079 EEMERAPERRDVCWSQRGEDGMCAGPLAGPALTF-DDCCCRQGRGWGAQCRPCPPRGAGS 1137
Query: 390 XXXXXXXXXKGF----AKLDGATCRDVDECALSAE--LCAGGTCVNTDGSYRCDCPPGLT 443
F L G RD D ++ C G CV G C+CP G
Sbjct: 1138 HCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQ 1197
Query: 444 LDST 447
LD++
Sbjct: 1198 LDAS 1201
Score = 171 bits (415), Expect = 6e-42
Identities = 126/383 (32%), Positives = 163/383 (42%), Gaps = 75/383 (19%)
Query: 79 DVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR--C 135
+ DEC + ++C G CV + C C GYR CVDV+ECE + C GR C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP-CGPGRGIC 632
Query: 136 HNTPGSFRCECLPGFTL--SNDGRTCLGLK-------LGWGVSCQACPAQGSELYAVLCP 186
NT GS+ C C G+ L GR+C+ L G G C P Y C
Sbjct: 633 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGH----YKCNCY 688
Query: 187 EG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCI-CDPGYHPDADGLCRDIDE 241
G S+ DI+EC P +CP G CEN ++CI C PGY G CRD++E
Sbjct: 689 PGYRLKASRPPVCEDIDECRD-PSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNE 747
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGD 301
C S C+ G C N GSF C C +G P+ + C D+DECE GD
Sbjct: 748 C-AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA-------------GD 793
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQ 361
+ CDNG C NT G F+C+C GY L C D +D +
Sbjct: 794 V-------------CDNGICSNTPGSFQCQCLSGYHLSRDRSHCED----------ID-E 829
Query: 362 CEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAEL 421
C+ P + +C + G +G + G C+D+DEC+ L
Sbjct: 830 CD--FPAACIGGDCINTNG-----------SYRCLCPQGHRLVGGRKCQDIDECSQDPSL 876
Query: 422 C-AGGTCVNTDGSYRCDCPPGLT 443
C G C N GSY C C G T
Sbjct: 877 CLPHGACKNLQGSYVCVCDEGFT 899
Score = 116 bits (279), Expect = 2e-25
Identities = 80/254 (31%), Positives = 109/254 (42%), Gaps = 27/254 (10%)
Query: 37 RDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRC 94
RD+DEC +C+ G+C NT Y C C+ GF C DVDEC +S C+ G C
Sbjct: 992 RDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVC 1051
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG--SFRCECLPGFTL 152
N+ G ++C C + + C+ +E E R C + G L G L
Sbjct: 1052 ENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPE-RRDVCWSQRGEDGMCAGPLAGPAL 1110
Query: 153 SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNG--------------GADI 198
+ D C GWG C+ CP +G+ + CP S+ N D
Sbjct: 1111 TFDD-CCCRQGRGWGAQCRPCPPRGAGSH---CPTSQSESNSFWDTSPLLLGKPPRDEDS 1166
Query: 199 NECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDEC-DMHQS--YCAGGQC 254
+E + C G C G C C G+ DA C DIDEC +++Q C +C
Sbjct: 1167 SEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERC 1226
Query: 255 RNTAGSFTCVCPEG 268
NT+GSF CVC G
Sbjct: 1227 VNTSGSFRCVCKAG 1240
Score = 104 bits (249), Expect = 7e-22
Identities = 97/380 (25%), Positives = 145/380 (38%), Gaps = 47/380 (12%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCLC 65
C G C N +G + C+C G+ G C+D+DEC +P +C G C+N GSY C+C
Sbjct: 836 CIGGDCINTNGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVC 894
Query: 66 EPGFAPTAAGY-CADVD------ECAA---DSMCKGGRCVNSEGSFQCVCE--AGYRPTA 113
+ GF PT + C +V+ EC D++ + +C C AG+
Sbjct: 895 DEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHC 954
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQAC 173
C E +C +G+ + + +P D C+ G + +
Sbjct: 955 EIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAH---RDIDECM--LFGSEICKEGK 1009
Query: 174 PAQGSELYAVLCPEGPSKDNG---GADINECTAVPGACPHGSCENLEPGYRCICDPG--Y 228
Y C +G D D++EC C +G CEN GYRC C P Y
Sbjct: 1010 CVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESN-CRNGVCENTRGGYRCACTPPAEY 1068
Query: 229 HPDADGLCRDIDECDM-------------HQSYCAGGQCRNTAGSFTCVCPEGTRHEPEL 275
P A C +E + CAG C C +G +
Sbjct: 1069 SP-AQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQC 1127
Query: 276 QLCRDI---DEC---EGETETHYIESDYERGDIPPTFPTRTELASPCD--NGRCINTHGG 327
+ C C + E+ + + S G P + E + C +GRC+ GG
Sbjct: 1128 RPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGG 1187
Query: 328 FECECELGYVLDATAQRCLD 347
CEC G+ LDA+ RC+D
Sbjct: 1188 AVCECPGGFQLDASRARCVD 1207
Score = 77.8 bits (183), Expect = 7e-14
Identities = 37/124 (29%), Positives = 60/124 (48%), Gaps = 6/124 (4%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ + +C D++ECA +C+ G C+N+ GS++CVC G+ +R C+ D+
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI-ADKP 399
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
EE+ +C +C+ P T C + WG CQ CP G+ + +
Sbjct: 400 EEKSLC----FRLVSPEHQCQ-HPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEI 454
Query: 185 CPEG 188
CP G
Sbjct: 455 CPAG 458
Score = 77.0 bits (181), Expect = 1e-13
Identities = 39/86 (45%), Positives = 47/86 (54%), Gaps = 8/86 (9%)
Query: 79 DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE--QR--VCRNGR 134
D DEC C GRCV G C C G++ A+R CVD+DEC E QR +C++ R
Sbjct: 1170 DSDECR----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSER 1225
Query: 135 CHNTPGSFRCECLPGFTLSNDGRTCL 160
C NT GSFRC C GF S C+
Sbjct: 1226 CVNTSGSFRCVCKAGFARSRPHGACV 1251
Score = 72.5 bits (170), Expect = 3e-12
Identities = 38/87 (43%), Positives = 47/87 (54%), Gaps = 10/87 (11%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAA-GYCADVDECAADS----MCKGG 92
D DECR C GRC G C C GF A+ C D+DEC + +CK
Sbjct: 1170 DSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSE 1224
Query: 93 RCVNSEGSFQCVCEAGYRPTATRGACV 119
RCVN+ GSF+CVC+AG+ + GACV
Sbjct: 1225 RCVNTSGSFRCVCKAGFARSRPHGACV 1251
Score = 64.5 bits (150), Expect = 7e-10
Identities = 29/67 (43%), Positives = 41/67 (61%), Gaps = 3/67 (4%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPR--VCRRGRCRNTAGSYTC 63
C +G C GG C C G++ + A C D+DECR+ N R +C+ RC NT+GS+ C
Sbjct: 1176 CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRC 1235
Query: 64 LCEPGFA 70
+C+ GFA
Sbjct: 1236 VCKAGFA 1242
Score = 59.3 bits (137), Expect = 3e-08
Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 6/81 (7%)
Query: 311 ELASP--CDNGRCINTHGGFECECELGYVLDATAQRCLDNR---RGSCWRRVV-DGQCEA 364
E A P C +G C+N G + C C G+ L + +C+ ++ + C+R V + QC+
Sbjct: 358 ECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQH 417
Query: 365 AAPELLLRQECCCSVGLAWGS 385
L RQ CCCSVG AWG+
Sbjct: 418 PLTTRLTRQLCCCSVGKAWGA 438
Score = 58.4 bits (135), Expect = 5e-08
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 19/117 (16%)
Query: 351 GSCWRRVVDGQ-CEA-AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX---------- 398
G C++ + Q C + P L +++CC S+G AWG
Sbjct: 277 GRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGE 336
Query: 399 ------KGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
+G+ +L+ C+D++ECA+ +C G C+N GSYRC CPPG +L + T
Sbjct: 337 VGADCPQGYKRLNSTHCQDINECAMPG-VCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Score = 55.6 bits (128), Expect = 3e-07
Identities = 36/95 (37%), Positives = 44/95 (46%), Gaps = 16/95 (16%)
Query: 147 LPGFTLSNDGRTCLGLKLGWGVS-CQACPA---QGSELYAVL-------CPEGPSKDNGG 195
LPG T D C + WG S C CP G + + CP+G + N
Sbjct: 294 LPGLTKQED--CCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNST 351
Query: 196 --ADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
DINEC A+PG C HG C N YRC+C PG+
Sbjct: 352 HCQDINEC-AMPGVCRHGDCLNNPGSYRCVCPPGH 385
Score = 48.8 bits (111), Expect = 4e-05
Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 4/62 (6%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG--FAPTAAGYCADV 80
C GY+ C+D++EC P VCR G C N GSY C+C PG P+ AD
Sbjct: 341 CPQGYKR-LNSTHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADK 398
Query: 81 DE 82
E
Sbjct: 399 PE 400
Score = 46.0 bits (104), Expect = 3e-04
Identities = 22/55 (40%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
C GY C+DI+EC M C G C N GS+ CVCP G P C
Sbjct: 341 CPQGYKRLNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Score = 44.0 bits (99), Expect = 0.001
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDST 447
G +C D++ECA LC GG C+N G Y+C+C PG L ++
Sbjct: 655 GRSCVDLNECA-KPHLCGDGGFCINFPGHYKCNCYPGYRLKAS 696
Score = 39.1 bits (87), Expect = 0.032
Identities = 18/38 (47%), Positives = 21/38 (55%), Gaps = 3/38 (7%)
Query: 407 ATCRDVDECALSAE---LCAGGTCVNTDGSYRCDCPPG 441
A C D+DEC + LC CVNT GS+RC C G
Sbjct: 1203 ARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG 1240
Score = 36.3 bits (80), Expect = 0.22
Identities = 12/32 (37%), Positives = 17/32 (53%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALC 36
G+C +G C N G + C+C PG+ G C
Sbjct: 363 GVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Score = 31.5 bits (68), Expect = 6.3
Identities = 11/33 (33%), Positives = 15/33 (45%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALC 36
G +C + C N G F C+CK G+ C
Sbjct: 1218 GLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1250
>AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens
cDNA FLJ16233 fis, clone FEBRA2028256, moderately
similar to FIBRILLIN 2 PRECURSOR. ).
Length = 872
Score = 234 bits (572), Expect = 5e-61
Identities = 149/451 (33%), Positives = 194/451 (43%), Gaps = 56/451 (12%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RG-RCRNTAGSYTCLCEPGF 69
C N +G + C C GY +GA+CRDVDEC D + C RG C+N G++ C+C PG
Sbjct: 287 CHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGM 346
Query: 70 APTAAGY--CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
P C D +EC A +C GRCVN+ GSF+C C+ G++P+ T C D+
Sbjct: 347 RPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDI----- 401
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
R G C C L + + C G GWG C+ CP G+ Y LC
Sbjct: 402 ----RQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLC 457
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
P G G D++EC + C HG C N +RC C GY PDA C D+DEC
Sbjct: 458 PHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQ 517
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDI-- 302
C C+NT GSF C CP G E + + C+D+DEC G
Sbjct: 518 VPKPCT-FLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTC 576
Query: 303 --PPTFPTR-------TELASP--CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRG 351
PP F E P C +G C N GG+ C C G+ + +C+D
Sbjct: 577 RCPPGFTQHHQACFDVNECDGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVD--EN 633
Query: 352 SCWRRVVDGQC-EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR 410
C + C A+ L C C G + L G C+
Sbjct: 634 EC--ALSPPTCGSASCRNTLGGFRCVCPSGFDFDQA-----------------LGG--CQ 672
Query: 411 DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
DVDECA C+ +C NT G + C CP G
Sbjct: 673 DVDECAGRRGPCS-YSCANTPGGFLCGCPQG 702
Score = 208 bits (509), Expect = 2e-53
Identities = 142/425 (33%), Positives = 181/425 (42%), Gaps = 50/425 (11%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVN 96
DV+EC +NP VC G C NT GS+ C C G++ G C D DEC+ C G C N
Sbjct: 190 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTN 249
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
G F+C C G+ P C D+DEC + RCHNT GS+ C C G+TL DG
Sbjct: 250 VIGGFECACADGFEP-GLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDG 308
Query: 157 RTCLGLKLGWGVSCQACPAQGSE------LYAVLCPEG----PSKDNGGADINECTAVPG 206
C + Q C A+G E +A +CP G P G D NEC A P
Sbjct: 309 AMCRDVD-ECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPD 367
Query: 207 ACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDE----CDMHQSYCAGGQCRNTAGS- 260
C +G C N +RC CD G+ P C DI + ++ Q+ C + A +
Sbjct: 368 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 427
Query: 261 FTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDY--ERGDIPPTFPTRTELASPCDN 318
C C G P +LC + + S Y E D+ LA C +
Sbjct: 428 AECCCGGGRGWGPRCELC-PLPGTSAYRKLCPHGSGYTAEGRDVDEC----RMLAHLCAH 482
Query: 319 GRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCS 378
G CIN+ G F C C+ GY DATA CLD S + C+ L C C
Sbjct: 483 GECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFL----CSCP 538
Query: 379 VGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
G + DG TC+D+DEC C CVNT G++ C C
Sbjct: 539 RGY-------------------LLEEDGRTCKDLDECTSRQHNCQ-FLCVNTVGAFTCRC 578
Query: 439 PPGLT 443
PPG T
Sbjct: 579 PPGFT 583
Score = 200 bits (487), Expect = 1e-50
Identities = 156/453 (34%), Positives = 188/453 (41%), Gaps = 77/453 (16%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C G C N+ GGFEC C G+E G C D+DEC NP +C RC NT GSY C
Sbjct: 239 GHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDIDECSLNPLLCAF-RCHNTEGSYLC 296
Query: 64 LCEPGFAPTAAG-YCADVDECA---ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG-AC 118
C G+ G C DVDECA D +G C N G+F CVC G RP G C
Sbjct: 297 TCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 356
Query: 119 VDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
D +EC Q +C NGRC NT GSFRC+C GF S C ++ G C A
Sbjct: 357 TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG---PCFA----- 408
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLE-PG---YRCICDPGYHPDAD 233
E+ +C S + EC G CE PG YR +C G A+
Sbjct: 409 -EVLQTMC-RSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE 466
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
G RD+DEC M CA G+C N+ GSF C C G + C D+DEC
Sbjct: 467 G--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDEC--------- 515
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSC 353
+++ PC C NT G F C C GY+L+ + C D C
Sbjct: 516 ----------------SQVPKPC-TFLCKNTKGSFLCSCPRGYLLEEDGRTCKD--LDEC 556
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVD 413
R C+ + C C GF + A C DV+
Sbjct: 557 TSR--QHNCQFLCVNTVGAFTCRCP--------------------PGFTQHHQA-CFDVN 593
Query: 414 ECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
EC C G C N G YRC CP G T S
Sbjct: 594 ECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHS 624
Score = 174 bits (424), Expect = 5e-43
Identities = 107/296 (36%), Positives = 141/296 (47%), Gaps = 30/296 (10%)
Query: 185 CPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDE 241
CP G S D G D +EC+ V C G+C N+ G+ C C G+ P C DIDE
Sbjct: 217 CPFGYSLDFTGINCVDTDECS-VGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDE 275
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETETHY--IESDYE 298
C ++ CA +C NT GS+ C CP G + +CRD+DEC +G+ + H +E
Sbjct: 276 CSLNPLLCAF-RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNL 334
Query: 299 RGDI----PP---TFPTRTE--------LASP--CDNGRCINTHGGFECECELGYVLDAT 341
G PP P E A P C NGRC+NT G F C+C+ G+ T
Sbjct: 335 IGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPT 394
Query: 342 AQRCLDNRRGSCWRRVVDGQCEA--AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK 399
C D R+G C+ V+ C + ++ E + R ECCC G WG +
Sbjct: 395 LTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYR 454
Query: 400 GFAKL-DGATC--RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAPL 452
G T RDVDEC + A LCA G C+N+ GS+RC C G T D+T T L
Sbjct: 455 KLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCL 510
Score = 166 bits (403), Expect = 2e-40
Identities = 143/493 (29%), Positives = 188/493 (38%), Gaps = 74/493 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G+CTNG+C N DG F C C GY G C D DEC C +G C N G +
Sbjct: 197 NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNVIGGFE 255
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF P C D+DEC+ + + RC N+EGS+ C C AGY C DVD
Sbjct: 256 CACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVD 315
Query: 123 ECEE-QRVC--RNGRCHNTPGSFRCECLPGF-TLSNDGRTCLGLKLGWGVSCQACPAQGS 178
EC + Q+ C R C N G+F C C PG L G C C AQ
Sbjct: 316 ECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC--------TDDNECHAQPD 367
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
LC G + G+ +C P C ++ G P + +CR
Sbjct: 368 -----LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQG------PCFAEVLQTMCR 416
Query: 238 DI---DECDMHQSYCAGG------QCR----NTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
+ E C GG +C ++ +CP G+ + E RD+DEC
Sbjct: 417 SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAE---GRDVDEC 473
Query: 285 --------EGE--TETHYIESDYERGDIPPTFPTR-------TELASPCDNGRCINTHGG 327
GE + G P T +++ PC C NT G
Sbjct: 474 RMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGS 532
Query: 328 FECECELGYVLDATAQRCLD-----NRRGSCWRRVVD--GQCEAAAPE-LLLRQECCCSV 379
F C C GY+L+ + C D +R+ +C V+ G P + C V
Sbjct: 533 FLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDV 592
Query: 380 GLAWG------SXXXXXXXXXXXXXKGFAK-LDGATCRDVDECALSAELCAGGTCVNTDG 432
G +GF + A C D +ECALS C +C NT G
Sbjct: 593 NECDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLG 652
Query: 433 SYRCDCPPGLTLD 445
+RC CP G D
Sbjct: 653 GFRCVCPSGFDFD 665
Score = 151 bits (366), Expect = 5e-36
Identities = 125/387 (32%), Positives = 158/387 (40%), Gaps = 46/387 (11%)
Query: 79 DVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN 137
DV+ECA + +C G CVN++GSF+C C GY T CVD DEC C G C N
Sbjct: 190 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTN 249
Query: 138 TPGSFRCECLPGFT-----LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKD 192
G F C C GF D C L C +GS Y CP G +
Sbjct: 250 VIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHN--TEGS--YLCTCPAGYTLR 305
Query: 193 NGGA---DINECTAVPGAC-PHG-SCENLEPGYRCICDPGYHP---DADGLCRDIDECDM 244
GA D++EC C G C+NL + C+C PG P +G C D +EC
Sbjct: 306 EDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEG-CTDDNECHA 364
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C G+C NTAGSF C C EG + P L C DI + G +++
Sbjct: 365 QPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ--GPCFAEVLQTMCRSLSSSS 422
Query: 305 TFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQR--CLDNRRGSCWRRVVDGQC 362
TR E C GR G+ CEL + +A R C + R VD +C
Sbjct: 423 EAVTRAECC--CGGGR------GWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVD-EC 473
Query: 363 EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK-LDGATCRDVDECALSAEL 421
A L EC S+G G+ TC D+DEC+ +
Sbjct: 474 RMLA-HLCAHGECINSLG-----------SFRCHCQAGYTPDATATTCLDMDECSQVPKP 521
Query: 422 CAGGTCVNTDGSYRCDCPPGLTLDSTG 448
C C NT GS+ C CP G L+ G
Sbjct: 522 CTF-LCKNTKGSFLCSCPRGYLLEEDG 547
Score = 140 bits (339), Expect = 9e-33
Identities = 81/239 (33%), Positives = 111/239 (46%), Gaps = 14/239 (5%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G C N G F C C+ GY + C D+DEC P+ C C+NT GS+ C C
Sbjct: 479 LCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSC 537
Query: 66 EPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ G C D+DEC + CVN+ G+F C C G+ T AC DV+EC
Sbjct: 538 PRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGF--TQHHQACFDVNEC 595
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL---- 180
+ C++G C N G +RC C GFT + C+ + +S C +
Sbjct: 596 DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVD-ENECALSPPTCGSASCRNTLGG 653
Query: 181 YAVLCPEGPSKDN--GGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ +CP G D GG D++EC G C + SC N G+ C C GY G C
Sbjct: 654 FRCVCPSGFDFDQALGGCQDVDECAGRRGPCSY-SCANTPGGFLCGCPQGYFRAGQGHC 711
Score = 116 bits (280), Expect = 1e-25
Identities = 65/179 (36%), Positives = 85/179 (47%), Gaps = 8/179 (4%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+C N G F C C PG+ + C DV+EC D P C+ G C+N G Y C C GF
Sbjct: 566 LCVNTVGAFTCRCPPGFTQHHQA--CFDVNEC-DGPHRCQHG-CQNQLGGYRCSCPQGFT 621
Query: 71 PTAA-GYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
+ C D +ECA + C C N+ G F+CVC +G+ G C DVDEC +R
Sbjct: 622 QHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRR 681
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
+ C NTPG F C C G+ + G G LG+ Q P + L + C E
Sbjct: 682 GPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSG--LGFSPGPQDTPDKEELLSSEACYE 738
Score = 107 bits (258), Expect = 6e-23
Identities = 86/265 (32%), Positives = 104/265 (39%), Gaps = 54/265 (20%)
Query: 189 PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQS 247
P D+ D+NEC PG C +G C N + +RC C GY D G+ C D DEC +
Sbjct: 182 PGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP 241
Query: 248 YCAGGQCRNTAGSFTCVCPEGTRHEPELQL-CRDIDECEGETETHYIESDYERGDIPPTF 306
C G C N G F C C +G EP L + C DIDEC + P
Sbjct: 242 -CGQGTCTNVIGGFECACADG--FEPGLMMTCEDIDEC----------------SLNPLL 282
Query: 307 PTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAA 366
A C N T G + C C GY L C D C DGQ + A
Sbjct: 283 -----CAFRCHN-----TEGSYLCTCPAGYTLREDGAMCRD--VDEC----ADGQQDCHA 326
Query: 367 PELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA--TCRDVDECALSAELCAG 424
+ EC +G G L G+ C D +EC +LC
Sbjct: 327 RGM----ECKNLIG-----------TFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVN 371
Query: 425 GTCVNTDGSYRCDCPPGLTLDSTGT 449
G CVNT GS+RCDC G T T
Sbjct: 372 GRCVNTAGSFRCDCDEGFQPSPTLT 396
>AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein
protein.
Length = 511
Score = 226 bits (552), Expect = 1e-58
Identities = 150/484 (30%), Positives = 205/484 (42%), Gaps = 71/484 (14%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NGIC N G F+C C GY + + C D+DEC D P C G C NT GSY CLC
Sbjct: 2 VCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINTNGSYRCLC 60
Query: 66 EPGFAPTAAGYCADVDECAAD-SMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
G C D+DEC+ D S+C G C N +GS+ CVC+ G+ PT + C +V++
Sbjct: 61 PQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQ 120
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ--ACPAQGSELY 181
++ C N + C+ + ++ C L GWG C+ CP S +
Sbjct: 121 PHHKKEC----YLNFDDTVFCDSVLATNVTQQ-ECCCSLGAGWGDHCEIYPCPVYSSAEF 175
Query: 182 AVLCPEGP--SKDN--------GGADINECTAVPG-ACPHGSCENLEPGYRCICDPGYHP 230
LCP+G ++DN DI+EC C G C N +PGY C C G++
Sbjct: 176 HSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYY 235
Query: 231 DADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE 289
D + L C D+DEC + +S C G C NT G + C C + P + C +
Sbjct: 236 DGNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPE------- 287
Query: 290 THYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC---- 345
E D + P + C GRC+N G + CEC +V + + C
Sbjct: 288 ----EMDVDECQDP----------AACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPE 333
Query: 346 -----LDNRRGSCW-RRVVDGQCEA--AAPELLLRQECCCSVGLAWGS--------XXXX 389
RR CW +R DG C A P L +CCC G WG+
Sbjct: 334 SPAERAPERRDVCWSQRGEDGMCAGPLAGPALTF-DDCCCRQGRGWGAQCRPCPPRGAGS 392
Query: 390 XXXXXXXXXKGF----AKLDGATCRDVDECALSAE--LCAGGTCVNTDGSYRCDCPPGLT 443
F L G RD D ++ C G CV G C+CP G
Sbjct: 393 HCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQ 452
Query: 444 LDST 447
LD++
Sbjct: 453 LDAS 456
Score = 139 bits (337), Expect = 2e-32
Identities = 97/290 (33%), Positives = 125/290 (43%), Gaps = 33/290 (11%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C G C N G+EC CK G+ C DVDEC D CR G C NT G Y C C
Sbjct: 212 ICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESN-CRNGVCENTRGGYRCAC 270
Query: 66 EPG--FAPTAAGYCA-----DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC 118
P ++P A C DVDEC + C+ GRCVN GS++C C + P + C
Sbjct: 271 TPPAEYSP-AQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDC 329
Query: 119 VDVDECEEQRVCRNGRCHNTPG--SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ E+ R C + G L G L+ D C GWG C+ CP +
Sbjct: 330 QLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDD-CCCRQGRGWGAQCRPCPPR 388
Query: 177 GSELYAVLCPEGPSKDNG--------------GADINECTAVPGACPHGSCENLEPGYRC 222
G+ + CP S+ N D +E + C G C G C
Sbjct: 389 GAGSH---CPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVC 445
Query: 223 ICDPGYHPDAD-GLCRDIDEC-DMHQS--YCAGGQCRNTAGSFTCVCPEG 268
C G+ DA C DIDEC +++Q C +C NT+GSF CVC G
Sbjct: 446 ECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG 495
Score = 80.2 bits (189), Expect = 1e-14
Identities = 97/384 (25%), Positives = 143/384 (37%), Gaps = 54/384 (14%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVD------ECR---DNPRVCRRGRCRNTAG 59
+G CKN+ G + C+C G+ + C +V+ EC D+ C N
Sbjct: 88 HGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVT- 146
Query: 60 SYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGAC 118
C C G G ++ C S + C + +G Q Y A R
Sbjct: 147 QQECCCSLG---AGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHR--- 200
Query: 119 VDVDECE--EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQ--AC 173
D+DEC +C+ G+C NT + C C GF + C+ + S C+ C
Sbjct: 201 -DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVC 259
Query: 174 P-AQGSELYAVLCPE--GPSKDN----GGADINECTAVPGACPHGSCENLEPGYRCICDP 226
+G A P P++ D++EC P AC G C NL YRC C P
Sbjct: 260 ENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQD-PAACRPGRCVNLPGSYRCECRP 318
Query: 227 GYHPDADGL-C-------------RDIDECDMHQSYCAGGQCRNTAGSFT-CVCPEGTRH 271
+ P G C RD+ + G A +F C C +G
Sbjct: 319 PWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGW 378
Query: 272 EPELQLCRDI---DEC---EGETETHYIESDYERGDIPPTFPTRTELASPCD--NGRCIN 323
+ + C C + E+ + + S G P + E + C +GRC+
Sbjct: 379 GAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVP 438
Query: 324 THGGFECECELGYVLDATAQRCLD 347
GG CEC G+ LDA+ RC+D
Sbjct: 439 RPGGAVCECPGGFQLDASRARCVD 462
Score = 77.0 bits (181), Expect = 1e-13
Identities = 39/86 (45%), Positives = 47/86 (54%), Gaps = 8/86 (9%)
Query: 79 DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE--QR--VCRNGR 134
D DEC C GRCV G C C G++ A+R CVD+DEC E QR +C++ R
Sbjct: 425 DSDECR----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSER 480
Query: 135 CHNTPGSFRCECLPGFTLSNDGRTCL 160
C NT GSFRC C GF S C+
Sbjct: 481 CVNTSGSFRCVCKAGFARSRPHGACV 506
Score = 72.5 bits (170), Expect = 3e-12
Identities = 38/87 (43%), Positives = 47/87 (54%), Gaps = 10/87 (11%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAA-GYCADVDECAADS----MCKGG 92
D DECR C GRC G C C GF A+ C D+DEC + +CK
Sbjct: 425 DSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSE 479
Query: 93 RCVNSEGSFQCVCEAGYRPTATRGACV 119
RCVN+ GSF+CVC+AG+ + GACV
Sbjct: 480 RCVNTSGSFRCVCKAGFARSRPHGACV 506
Score = 39.1 bits (87), Expect = 0.032
Identities = 18/38 (47%), Positives = 21/38 (55%), Gaps = 3/38 (7%)
Query: 407 ATCRDVDECALSAE---LCAGGTCVNTDGSYRCDCPPG 441
A C D+DEC + LC CVNT GS+RC C G
Sbjct: 458 ARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG 495
Score = 31.5 bits (68), Expect = 6.3
Identities = 11/33 (33%), Positives = 15/33 (45%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALC 36
G +C + C N G F C+CK G+ C
Sbjct: 473 GLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 505
Score = 31.1 bits (67), Expect = 8.4
Identities = 11/25 (44%), Positives = 15/25 (60%)
Query: 420 ELCAGGTCVNTDGSYRCDCPPGLTL 444
++C G C NT GS++C C G L
Sbjct: 1 DVCDNGICSNTPGSFQCQCLSGYHL 25
>X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein.
Length = 517
Score = 214 bits (522), Expect = 6e-55
Identities = 102/275 (37%), Positives = 145/275 (52%), Gaps = 14/275 (5%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+CT+G C+N G F+C C G+ SE C D+DECR +P +C RG+C NT G + C C
Sbjct: 242 LCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKC 301
Query: 66 EPGFAP--TAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+ G+ C D+DEC D +C+GG C N+EGS++C C G++ + AC+D++
Sbjct: 302 DEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDIN 361
Query: 123 ECE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQACPAQG 177
ECE +C NGRC N G ++C C PG+ + D C+ + + G ++G
Sbjct: 362 ECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEG 421
Query: 178 SELYAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD- 233
S Y C G DI+EC P C G C N+ YRC+C G+ D
Sbjct: 422 S--YECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDM 479
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C D++ECD++ + C G C NT GSF C C G
Sbjct: 480 KTCVDVNECDLNPNICLSGTCENTKGSFICHCDMG 514
Score = 203 bits (495), Expect = 1e-51
Identities = 112/313 (35%), Positives = 158/313 (50%), Gaps = 41/313 (13%)
Query: 37 RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDECA-ADSMCKGGRC 94
+D++EC+ P +C G+CRNT GS+ C C+ GFA + C D+DEC + +C G+C
Sbjct: 231 KDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQC 290
Query: 95 VNSEGSFQCVCEAGYRPT-ATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTL 152
VN+ G F+C C+ GY C+D+DEC+ + +CR G CHNT GS+RCEC PG L
Sbjct: 291 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 350
Query: 153 SNDGRTCLGLKLGWGVSCQACP-AQGSEL---YAVLCPEGPSKDNGG---ADINECTAVP 205
S + C+ + +S CP + L Y C G DI+EC+ +
Sbjct: 351 SPNISACIDIN-ECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMN 409
Query: 206 GACPHGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
G C C N E Y C C PG+ PD C DIDEC+ + + C GGQC N G + C
Sbjct: 410 GGC-ETFCTNSEGSYECSCQPGFALMPDQRS-CTDIDECEDNPNICDGGQCTNIPGEYRC 467
Query: 264 VCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
+C +G +++ C D++EC D+ P C +G C N
Sbjct: 468 LCYDGFMASEDMKTCVDVNEC----------------DLNPNI---------CLSGTCEN 502
Query: 324 THGGFECECELGY 336
T G F C C++GY
Sbjct: 503 TKGSFICHCDMGY 515
Score = 192 bits (467), Expect = 3e-48
Identities = 146/487 (29%), Positives = 195/487 (40%), Gaps = 86/487 (17%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRD----------VD-ECRDNPR-VCRRGRC 54
C NG+CKN G F C C +C + +D C N + +C
Sbjct: 20 CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC 79
Query: 55 RNTAGSY------TC----LCEPGFAPTAAGYCADVDECAA-DSMCKGGRCVNSEGSFQC 103
++ G+ C +C G++ C D+DEC +CK G CVN+ GSF+C
Sbjct: 80 CSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKC 139
Query: 104 VCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
C +G AT C+D+ R C C LP C +
Sbjct: 140 QCPSGMTLDATGRICLDI---------RLETCFLRYEDEECT-LPIAGRHRMDACCCSVG 189
Query: 164 LGWGVS-CQACPAQGSELYAVLCPEGP---SKD--NGG---ADINECTAVPGACPHGSCE 214
WG C+ CP + + Y LCP GP +K+ NG DINEC +P C HG C
Sbjct: 190 AAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCR 249
Query: 215 NLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE- 272
N ++C CD G+ D++ C DIDEC + C GQC NT G F C C EG
Sbjct: 250 NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGF 309
Query: 273 PELQLCRDIDECEGET------ETHYIESDYERGDIPPTFPTRTEL------------AS 314
++ C DIDEC+ + H E Y R + PP + A
Sbjct: 310 MMMKNCMDIDECQRDPLLCRGGVCHNTEGSY-RCECPPGHQLSPNISACIDINECELSAH 368
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
C NGRC+N G ++C C GY C+D S +++G CE E
Sbjct: 369 LCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECS----IMNGGCETFCTNSEGSYE 424
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSY 434
C C G A D +C D+DEC + +C GG C N G Y
Sbjct: 425 CSCQPGFA-------------------LMPDQRSCTDIDECEDNPNICDGGQCTNIPGEY 465
Query: 435 RCDCPPG 441
RC C G
Sbjct: 466 RCLCYDG 472
Score = 180 bits (437), Expect = 1e-44
Identities = 95/237 (40%), Positives = 120/237 (50%), Gaps = 19/237 (8%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGAL-CRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
+C G C N G FEC C GYESG C D+DEC+ +P +CR G C NT GSY C
Sbjct: 284 LCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCE 343
Query: 65 CEPG--FAPTAAGYCADVDECAADS-MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C PG +P + C D++EC + +C GRCVN G +QC C GY T R CVD+
Sbjct: 344 CPPGHQLSPNISA-CIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDI 402
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-------KLGWGVSCQACP 174
DEC C N+ GS+ C C PGF L D R+C + + G C P
Sbjct: 403 DECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIP 462
Query: 175 AQGSELYAVLCPEG--PSKD-NGGADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
+ Y LC +G S+D D+NEC P C G+CEN + + C CD GY
Sbjct: 463 GE----YRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGY 515
Score = 155 bits (375), Expect = 4e-37
Identities = 111/349 (31%), Positives = 152/349 (43%), Gaps = 48/349 (13%)
Query: 49 CRRGRCRNTAGSYTCLCE--PGFAP----TAAGYCADVDECAA-DSMCKGGRCVNSEGSF 101
C RNT Y LC PGFA + D++EC S+C G+C N+ GSF
Sbjct: 197 CEECPMRNTP-EYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSF 255
Query: 102 QCVCEAGYRPTATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTLS-NDGRTC 159
+C C++G+ + C D+DEC +C G+C NTPG F C+C G+ + C
Sbjct: 256 KCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNC 315
Query: 160 LGLKLGWG--VSCQACPAQGSE-LYAVLCPEGPS-KDNGGA--DINECTAVPGACPHGSC 213
+ + + C+ +E Y CP G N A DINEC CP+G C
Sbjct: 316 MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRC 375
Query: 214 ENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE 272
NL Y+C C+PGYH D L C DIDEC + C C N+ GS+ C C G
Sbjct: 376 VNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETF-CTNSEGSYECSCQPGFALM 434
Query: 273 PELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECEC 332
P+ + C DIDECE D P + CD G+C N G + C C
Sbjct: 435 PDQRSCTDIDECE---------------DNP----------NICDGGQCTNIPGEYRCLC 469
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRV-VDGQCEAAAPELLLRQECCCSVG 380
G++ + C+D + + G CE + C C +G
Sbjct: 470 YDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFI----CHCDMG 514
Score = 140 bits (339), Expect = 9e-33
Identities = 59/137 (43%), Positives = 82/137 (59%), Gaps = 1/137 (0%)
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLL 371
L+SPC NG C N+ G F CEC LD T C++ +G+CW+ V+DG+CE L
Sbjct: 16 LSSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATL 75
Query: 372 RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTD 431
+ +CC S+G AWGS KG++++ G C D+DEC + +C G CVNT
Sbjct: 76 KSQCCSSLGAAWGS-PCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTR 134
Query: 432 GSYRCDCPPGLTLDSTG 448
GS++C CP G+TLD+TG
Sbjct: 135 GSFKCQCPSGMTLDATG 151
Score = 136 bits (330), Expect = 1e-31
Identities = 61/150 (40%), Positives = 85/150 (56%), Gaps = 6/150 (4%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C NG C N+ G ++C C PGY S + C D+DEC C C N+ GSY C C
Sbjct: 369 LCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETF-CTNSEGSYECSC 427
Query: 66 EPGFA--PTAAGYCADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+PGFA P C D+DEC + ++C GG+C N G ++C+C G+ + CVDV+
Sbjct: 428 QPGFALMPDQRS-CTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVN 486
Query: 123 ECE-EQRVCRNGRCHNTPGSFRCECLPGFT 151
EC+ +C +G C NT GSF C C G++
Sbjct: 487 ECDLNPNICLSGTCENTKGSFICHCDMGYS 516
Score = 129 bits (312), Expect = 2e-29
Identities = 111/369 (30%), Positives = 153/369 (41%), Gaps = 53/369 (14%)
Query: 87 SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCEC 146
S C G C NS GSF C C + T+ C++ + G C T RCE
Sbjct: 18 SPCINGVCKNSPGSFICECSSESTLDPTKTICIETIK---------GTCWQTVIDGRCEI 68
Query: 147 -LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG--ADINECTA 203
+ G TL + + C L WG C C +C +G S+ G DI+EC
Sbjct: 69 NINGATLKS--QCCSSLGAAWGSPCTLCQVD------PICGKGYSRIKGTQCEDIDECEV 120
Query: 204 VPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDI--DEC-----DMHQSYCAGGQCR 255
PG C +G C N ++C C G DA G +C DI + C D + G+ R
Sbjct: 121 FPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHR 180
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE---L 312
A + GT E + R+ E E + E + P F E +
Sbjct: 181 MDACCCSVGAAWGTEECEECPM-RNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMI 239
Query: 313 ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLR 372
S C +G+C NT G F+C C+ G+ LD+ + C D +D +C +P+L R
Sbjct: 240 PSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTD----------ID-ECR-ISPDLCGR 287
Query: 373 QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDG 432
+C + G GF + C D+DEC LC GG C NT+G
Sbjct: 288 GQCVNTPG-------DFECKCDEGYESGFMMM--KNCMDIDECQRDPLLCRGGVCHNTEG 338
Query: 433 SYRCDCPPG 441
SYRC+CPPG
Sbjct: 339 SYRCECPPG 347
Score = 99.1 bits (236), Expect = 3e-20
Identities = 52/143 (36%), Positives = 67/143 (46%), Gaps = 12/143 (8%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C NG C+NT G F+C+C G LDAT + CLD R +C+ R D +C C
Sbjct: 125 CKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDAC 184
Query: 376 CCSVGLAWGSXXXXXXXXXXX--------XXKGFAKLDGAT----CRDVDECALSAELCA 423
CCSVG AWG+ GFA + +D++EC + LC
Sbjct: 185 CCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCT 244
Query: 424 GGTCVNTDGSYRCDCPPGLTLDS 446
G C NT GS++C C G LDS
Sbjct: 245 HGKCRNTIGSFKCRCDSGFALDS 267
Score = 72.5 bits (170), Expect = 3e-12
Identities = 27/68 (39%), Positives = 39/68 (57%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N +C G C NI G + C+C G+ + + C DV+EC NP +C G C NT GS+
Sbjct: 449 NPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFI 508
Query: 63 CLCEPGFA 70
C C+ G++
Sbjct: 509 CHCDMGYS 516
Score = 33.5 bits (73), Expect = 1.6
Identities = 13/35 (37%), Positives = 18/35 (51%)
Query: 244 MHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
M S C G C+N+ GSF C C + +P +C
Sbjct: 15 MLSSPCINGVCKNSPGSFICECSSESTLDPTKTIC 49
Score = 33.5 bits (73), Expect = 1.6
Identities = 13/28 (46%), Positives = 16/28 (57%)
Query: 422 CAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
C G C N+ GS+ C+C TLD T T
Sbjct: 20 CINGVCKNSPGSFICECSSESTLDPTKT 47
>AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming growth
factor-beta binding protein 4 protein.
Length = 669
Score = 185 bits (451), Expect = 2e-46
Identities = 98/253 (38%), Positives = 129/253 (50%), Gaps = 13/253 (5%)
Query: 26 GYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAA 85
G++ + G+ C DVDEC +N C C N+ GS+ C P G C DVDEC++
Sbjct: 5 GFQPNAAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSS 63
Query: 86 DSMCKG--GRCVNSEGSFQCVCEAGYR-PTATRGACVDVDECEEQRVC-RNGRCHNTPGS 141
+ G G C N+EGSF+C C GYR P+ G C DV+EC E C +G C NT GS
Sbjct: 64 GAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGS 123
Query: 142 FRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSE-LYAVLCPEGPSKDNGGA--- 196
F C C PG+ G +CL + + CQ+ ++ + +CP G A
Sbjct: 124 FACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL 183
Query: 197 DINECTAV-PGACPHGSCENLEPGYRCI--CDPGYHPDADGLCRDIDECDMHQSYCAGGQ 253
D++EC P C CEN YRC+ CDPGYH +G C D++EC+ Q C
Sbjct: 184 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVCGAAL 243
Query: 254 CRNTAGSFTCVCP 266
C N GSF CVCP
Sbjct: 244 CENVEGSFLCVCP 256
Score = 166 bits (404), Expect = 1e-40
Identities = 142/423 (33%), Positives = 180/423 (42%), Gaps = 55/423 (13%)
Query: 68 GFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQC-VCEAGYRPTATRGACVDVDECE 125
GF P AAG C DVDEC C G CVNS GSFQC C +G+ RG C DVDEC
Sbjct: 5 GFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHH--LHRGRCTDVDECS 62
Query: 126 EQRV-CR-NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--- 180
C +G C NT GSFRC C PG+ + GR + + C G L
Sbjct: 63 SGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS-GRPGPCADVNECLEGDFCFPHGECLNTD 121
Query: 181 --YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-G 234
+A C G GA D++EC+ C G C N + + CIC PG+ D
Sbjct: 122 GSFACTCAPGYRPGPRGASCLDVDECSE-EDLCQSGICTNTDGSFECICPPGHRAGPDLA 180
Query: 235 LCRDIDEC-DMHQSYCAGGQCRNTAGSFTCV--CPEGTRHEPELQLCRDIDECEG-ETET 290
C D+DEC + + C +C N+ GS+ CV C G PE C D++ECE +
Sbjct: 181 SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPE-GTCDDVNECETLQGVC 239
Query: 291 HYIESDYERGDIPPTFPTRTELASPCDNGRCI--NTHGGF----ECECELGYVLDATAQR 344
+ G P E P GRC+ T G + + VL A
Sbjct: 240 GAALCENVEGSFLCVCPNSPEEFDPM-TGRCVPPRTSAGMFPGSQPQAPASPVLPARPPP 298
Query: 345 CLDNRRGSCWRRVVDG----QC--EAAAPE----LLLR----QECCCSVGLAWGS----- 385
RR S R+ G +C + AAP+ +L R QECCC+VG WGS
Sbjct: 299 PPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQ 358
Query: 386 ----XXXXXXXXXXXXXKGFAKLDG--ATCRDVDECALSAE-LCAGGTCVNTDGSYRCDC 438
+G+ G + RDVDEC L + +C G CVNT Y C C
Sbjct: 359 QCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYC 418
Query: 439 PPG 441
G
Sbjct: 419 SNG 421
Score = 162 bits (394), Expect = 2e-39
Identities = 90/232 (38%), Positives = 111/232 (47%), Gaps = 17/232 (7%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCLC 65
C C N G F+C P G C DVDEC C G C NT GS+ C C
Sbjct: 27 CPGQECVNSPGSFQCRACPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSC 85
Query: 66 EPGF-APTAA-GYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
PG+ AP+ G CADV+EC C G C+N++GSF C C GYRP +C+DVD
Sbjct: 86 APGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVD 145
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL--------GLKLGWGVSCQACP 174
EC E+ +C++G C NT GSF C C PG D +CL G L C+ P
Sbjct: 146 ECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP 205
Query: 175 AQGSELYAVLCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCIC 224
GS C G G D+NEC + G C CEN+E + C+C
Sbjct: 206 --GSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVCGAALCENVEGSFLCVC 255
Score = 116 bits (278), Expect = 2e-25
Identities = 51/104 (49%), Positives = 64/104 (61%), Gaps = 4/104 (3%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCL 64
+C +GIC N DG FECIC PG+ +G + A C DVDECR+ P +C RC N+ GSY C+
Sbjct: 152 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 211
Query: 65 --CEPGFAPTAAGYCADVDEC-AADSMCKGGRCVNSEGSFQCVC 105
C+PG+ G C DV+EC +C C N EGSF CVC
Sbjct: 212 RDCDPGYHAGPEGTCDDVNECETLQGVCGAALCENVEGSFLCVC 255
Score = 107 bits (257), Expect = 8e-23
Identities = 85/277 (30%), Positives = 112/277 (40%), Gaps = 28/277 (10%)
Query: 6 MCTNGICKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY-- 61
+C + C+N G + C+ C PGY +G EG C DV+EC VC C N GS+
Sbjct: 195 LCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVNECETLQGVCGAALCENVEGSFLC 253
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C P G C V + M G + + S P R +
Sbjct: 254 VCPNSPEEFDPMTGRC--VPPRTSAGMFPGSQ-PQAPASPVLPARPPPPPLPRRPST--- 307
Query: 122 DECEEQRVCRNGR--CH-NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC--QACPAQ 176
Q +GR C+ +T C+ + ++ C + GWG C Q CP
Sbjct: 308 ---PRQGPVGSGRRECYFDTAAPDACDNILARNVTWQ-ECCCTVGEGWGSGCRIQQCPGT 363
Query: 177 GSELYAVLCPEG-----PSKDNG-GADINECTAVPG-ACPHGSCENLEPGYRCICDPGYH 229
+ Y LCP G PS D D++EC C G C N PGY C C GY+
Sbjct: 364 ETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY 423
Query: 230 PDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
L C D DEC + C GG+C NT GS+ C C
Sbjct: 424 YHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 460
Score = 90.2 bits (214), Expect = 1e-17
Identities = 58/157 (36%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Query: 34 ALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADVDECA-ADSMCK 90
+L RDVDEC+ +VC+ G C NTA Y+C C G + T C D DECA + C+
Sbjct: 386 SLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACE 445
Query: 91 GGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN-GRCHNTPGSFRCECLPG 149
GGRCVN+ GS+ C CE ++ CV E Q + N G C G+ P
Sbjct: 446 GGRCVNTVGSYHCTCEPPLVLDGSQRRCV---SNESQSLDDNLGVCWQEVGADLVCSHPR 502
Query: 150 FTLSNDGRTCLGL-KLGWGVSCQACPAQGSELYAVLC 185
C L WG+ C CPAQ S+ + LC
Sbjct: 503 LDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC 539
Score = 87.4 bits (207), Expect = 9e-17
Identities = 81/258 (31%), Positives = 94/258 (36%), Gaps = 54/258 (20%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAG-GQCR 255
D++EC ACP C N ++C P H G C D+DEC C G C
Sbjct: 17 DVDECENHL-ACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHCT 75
Query: 256 NTAGSFTCVCPEGTRHEPELQ-LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NT GSF C C G R C D++EC +E D+ FP
Sbjct: 76 NTEGSFRCSCAPGYRAPSGRPGPCADVNEC--------LEGDF-------CFP------- 113
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
+G C+NT G F C C GY CLD S G C E
Sbjct: 114 ---HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSF----E 166
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECA-LSAELCAGGTCVNTDGS 433
C C G G D A+C DVDEC LC C N+ GS
Sbjct: 167 CICPPGHRAGP-------------------DLASCLDVDECRERGPALCGSQRCENSPGS 207
Query: 434 YRC--DCPPGLTLDSTGT 449
YRC DC PG GT
Sbjct: 208 YRCVRDCDPGYHAGPEGT 225
Score = 86.6 bits (205), Expect = 2e-16
Identities = 47/120 (39%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Query: 49 CRRGRCRNT-AGSYTCLCEPG---FAPTA-AGYCADVDECAA--DSMCKGGRCVNSEGSF 101
CR +C T Y LC G AP+ DVDEC D +CK G CVN+ +
Sbjct: 355 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 414
Query: 102 QCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
C C GY R C+D DEC +E+ C GRC NT GS+ C C P L R C+
Sbjct: 415 SCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 474
Score = 81.8 bits (193), Expect = 5e-15
Identities = 63/202 (31%), Positives = 79/202 (39%), Gaps = 43/202 (21%)
Query: 201 CTAVPG---ACPHGSCENLEPG-YRCICDPG---YHPDAD-GLCRDIDECDMHQSY-CAG 251
CT G C C E Y+ +C G P D L RD+DEC + + C
Sbjct: 345 CTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKS 404
Query: 252 GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
G C NTA ++C C G + + C D DEC E
Sbjct: 405 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPA--------------------- 443
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRC-------LDNRRGSCWRRV-VDGQC- 362
C+ GRC+NT G + C CE VLD + +RC LD+ G CW+ V D C
Sbjct: 444 ----CEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCS 499
Query: 363 EAAAPELLLRQECCCSVGLAWG 384
ECCC G AWG
Sbjct: 500 HPRLDRQATYTECCCLYGEAWG 521
Score = 70.5 bits (165), Expect = 1e-11
Identities = 28/62 (45%), Positives = 34/62 (54%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G+C N G+ C C GY ++ C D DEC D C GRC NT GSY C C
Sbjct: 401 VCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 460
Query: 66 EP 67
EP
Sbjct: 461 EP 462
Score = 52.0 bits (119), Expect = 4e-06
Identities = 22/39 (56%), Positives = 23/39 (58%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
C D DECA C GG CVNT GSY C C P L LD +
Sbjct: 431 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGS 469
Score = 48.0 bits (109), Expect = 7e-05
Identities = 21/44 (47%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 409 CRDVDECALSAELCAG-GTCVNTDGSYRCDCPPGLTLDSTGTAP 451
C DVDEC+ A C G C NT+GS+RC C PG S P
Sbjct: 55 CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP 98
Score = 31.1 bits (67), Expect = 8.4
Identities = 12/30 (40%), Positives = 14/30 (46%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDP 226
D +EC AC G C N Y C C+P
Sbjct: 433 DNDECADEEPACEGGRCVNTVGSYHCTCEP 462
>X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein.
Length = 1184
Score = 177 bits (432), Expect = 5e-44
Identities = 129/376 (34%), Positives = 173/376 (46%), Gaps = 66/376 (17%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSY 61
+ G C +C + G C C PGY ++G C D++EC + C RG C NT GS+
Sbjct: 685 DNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSF 743
Query: 62 TCL----CEPGFAPTAAGYCADVDECAADS-MCKGG-RCVNSEGSFQCV----CEAGYRP 111
C CEPG+A G C DVDECA + C+ G C N++GSF C C G+
Sbjct: 744 HCYKALTCEPGYA-LKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQ 802
Query: 112 TATRGACVDVDECEE-QRVCRNG-RCHNTPGSFRCE-----CLPGFTLSNDGRTCLGL-- 162
G CVD++EC CR G C NT GS+ C+ C G+ S+DG C+ +
Sbjct: 803 DP-EGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNE 861
Query: 163 ------KLGWGVSCQACPAQGSELYAVLCPEGPSKD---NGGADINECTAVPGACPHGSC 213
+ G G C P GS Y C G +D G D+NEC A PG +C
Sbjct: 862 CETGVHRCGEGQVCHNLP--GS--YRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTC 917
Query: 214 ENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE 272
EN YRC C G+ ADG C D++EC+ + C+ +C N GS+ C C +G +
Sbjct: 918 ENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQ-ECANIYGSYQCYCRQGYQLA 974
Query: 273 PELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECEC 332
+ C DIDEC + I TF RC+N G ++C C
Sbjct: 975 EDGHTCTDIDECA------------QGAGILCTF-------------RCLNVPGSYQCAC 1009
Query: 333 -ELGYVLDATAQRCLD 347
E GY + A + C D
Sbjct: 1010 PEQGYTMTANGRSCKD 1025
Score = 175 bits (426), Expect = 3e-43
Identities = 123/361 (34%), Positives = 162/361 (44%), Gaps = 46/361 (12%)
Query: 7 CTNGI-CKNIDGGFECI----CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGS 60
C+ G C N G F C C+PGY +G C DVDEC C+ G C+NT GS
Sbjct: 730 CSRGEHCVNTLGSFHCYKALTCEPGYAL-KDGE-CEDVDECAMGTHTCQPGFLCQNTKGS 787
Query: 61 YTCL----CEPGFAPTAAGYCADVDECAADSM-CKGG-RCVNSEGSFQC-----VCEAGY 109
+ C C GF G C D++EC + S C+ G C+N+ GS+ C +C GY
Sbjct: 788 FYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGY 847
Query: 110 RPTATRGACVDVDECEEQ-RVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW- 166
+ CVDV+ECE C G+ CHN PGS+RC+C GF GR C+ + W
Sbjct: 848 HASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWA 907
Query: 167 --GVSCQACPAQGSELYAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYR 221
G CQ Y C G + D+NEC A C C N+ Y+
Sbjct: 908 SPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA--QRCSQ-ECANIYGSYQ 964
Query: 222 CICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE-GTRHEPELQLCR 279
C C GY DG C DIDEC +C N GS+ C CPE G + C+
Sbjct: 965 CYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCK 1024
Query: 280 DIDECE------GETET-HYIESDYE--RGDIPPTFPTRTELASPCDNGRCINTHGGFEC 330
D+DEC E ET H I+ + R + PP + ++ + C+ C H EC
Sbjct: 1025 DVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK--TKCERTTC---HDFLEC 1079
Query: 331 E 331
+
Sbjct: 1080 Q 1080
Score = 136 bits (328), Expect = 2e-31
Identities = 133/469 (28%), Positives = 177/469 (37%), Gaps = 85/469 (18%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C + +C N G + C C PG+ +G CR P + ++
Sbjct: 613 GELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGH-PPQPEAPQEPALKSEFSQVAS 670
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
P P + C + CK C GS C C GY A +C D++E
Sbjct: 671 NTIPLPLPQP-------NTCKDNGPCKQV-CSTVGGSAICSCFPGYAIMADGVSCEDINE 722
Query: 124 C-EEQRVCRNGR-CHNTPGSFRC----ECLPGFTLSNDGRTCLGLKLGWGV-SCQA---C 173
C + C G C NT GSF C C PG+ L DG + G +CQ C
Sbjct: 723 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGECEDVDECAMGTHTCQPGFLC 781
Query: 174 PAQGSELYAVL---CPEGPSKDNGG--ADINECTAVPGACPHG-SCENLEPGYRC----- 222
Y C +G +D G DINECT++ C G SC N Y C
Sbjct: 782 QNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 841
Query: 223 ICDPGYHPDADGL-CRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRD 280
IC GYH DG C D++EC+ C GQ C N GS+ C C G + + + C D
Sbjct: 842 ICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCID 901
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDA 340
++EC P R C + C NT G + C C G++L A
Sbjct: 902 VNECWAS-------------------PGRL-----CQH-TCENTLGSYRCSCASGFLLAA 936
Query: 341 TAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKG 400
+RC D R C + +C C G
Sbjct: 937 DGKRCEDVNECEAQR------CSQECANIYGSYQCYCRQGYQLAE--------------- 975
Query: 401 FAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCP-PGLTLDSTG 448
DG TC D+DECA A + C+N GSY+C CP G T+ + G
Sbjct: 976 ----DGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
Score = 111 bits (267), Expect = 5e-24
Identities = 115/432 (26%), Positives = 154/432 (35%), Gaps = 79/432 (18%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNS 97
D DEC P + C NT GSY C C PGF+ G + + S
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGR 157
E S Q P C D C++ C GS C C PG+ + DG
Sbjct: 664 EFS-QVASNTIPLPLPQPNTCKDNGPCKQV-------CSTVGGSAICSCFPGYAIMADGV 715
Query: 158 TCLGLK--------LGWGVSCQACPAQGSELYAVLCPEGPS-KDNGGADINECTAVPGAC 208
+C + G C A+ C G + KD D++EC C
Sbjct: 716 SCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTC 775
Query: 209 PHGS-CENLEPGYRCI----CDPGYHPDADGLCRDIDECDMHQSYCAGG-QCRNTAGSFT 262
G C+N + + C C G+ D +G C DI+EC C G C NT GS+T
Sbjct: 776 QPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYT 835
Query: 263 C-----VCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCD 317
C +C G + C D++ECE T H C
Sbjct: 836 CQRNPLICARGYHASDDGAKCVDVNECE--TGVHR-----------------------CG 870
Query: 318 NGR-CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECC 376
G+ C N G + C+C+ G+ DA + C+D CW C+ L C
Sbjct: 871 EGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE--CWASP-GRLCQHTCENTLGSYRCS 927
Query: 377 CSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRC 436
C+ G + DG C DV+EC A+ C+ C N GSY+C
Sbjct: 928 CASGFLLAA-------------------DGKRCEDVNEC--EAQRCSQ-ECANIYGSYQC 965
Query: 437 DCPPGLTLDSTG 448
C G L G
Sbjct: 966 YCRQGYQLAEDG 977
Score = 48.0 bits (109), Expect = 7e-05
Identities = 66/263 (25%), Positives = 88/263 (33%), Gaps = 41/263 (15%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQ 253
G D +EC +PG C N Y C C PG+ DG CR + H Q
Sbjct: 602 GDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRP----EGHPPQPEAPQ 657
Query: 254 CRNTAGSFTCVCPEGTRHE-PELQLCRDIDECEGETET---HYIESDYERGDIPPTFPTR 309
F+ V P+ C+D C+ T I S + I +
Sbjct: 658 EPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSC 717
Query: 310 TEL------ASPCDNG-RCINTHGGFEC----ECELGYVLDATAQRCLDNRRGSCWRRVV 358
++ C G C+NT G F C CE GY L
Sbjct: 718 EDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK------------------- 758
Query: 359 DGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALS 418
DG+CE E + C L + GF + C D++EC
Sbjct: 759 DGECE-DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSL 817
Query: 419 AELCAGG-TCVNTDGSYRCDCPP 440
+E C G +C+NT GSY C P
Sbjct: 818 SEPCRPGFSCINTVGSYTCQRNP 840
>BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein.
Length = 1184
Score = 177 bits (432), Expect = 5e-44
Identities = 129/376 (34%), Positives = 173/376 (46%), Gaps = 66/376 (17%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSY 61
+ G C +C + G C C PGY ++G C D++EC + C RG C NT GS+
Sbjct: 685 DNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSF 743
Query: 62 TCL----CEPGFAPTAAGYCADVDECAADS-MCKGG-RCVNSEGSFQCV----CEAGYRP 111
C CEPG+A G C DVDECA + C+ G C N++GSF C C G+
Sbjct: 744 HCYKALTCEPGYA-LKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQ 802
Query: 112 TATRGACVDVDECEE-QRVCRNG-RCHNTPGSFRCE-----CLPGFTLSNDGRTCLGL-- 162
G CVD++EC CR G C NT GS+ C+ C G+ S+DG C+ +
Sbjct: 803 DP-EGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNE 861
Query: 163 ------KLGWGVSCQACPAQGSELYAVLCPEGPSKD---NGGADINECTAVPGACPHGSC 213
+ G G C P GS Y C G +D G D+NEC A PG +C
Sbjct: 862 CETGVHRCGEGQVCHNLP--GS--YRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTC 917
Query: 214 ENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHE 272
EN YRC C G+ ADG C D++EC+ + C+ +C N GS+ C C +G +
Sbjct: 918 ENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQ-ECANIYGSYQCYCRQGYQLA 974
Query: 273 PELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECEC 332
+ C DIDEC + I TF RC+N G ++C C
Sbjct: 975 EDGHTCTDIDECA------------QGAGILCTF-------------RCLNVPGSYQCAC 1009
Query: 333 -ELGYVLDATAQRCLD 347
E GY + A + C D
Sbjct: 1010 PEQGYTMTANGRSCKD 1025
Score = 175 bits (425), Expect = 4e-43
Identities = 123/361 (34%), Positives = 162/361 (44%), Gaps = 46/361 (12%)
Query: 7 CTNGI-CKNIDGGFECI----CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGS 60
C+ G C N G F C C+PGY +G C DVDEC C+ G C+NT GS
Sbjct: 730 CSRGEHCVNTLGSFHCYKALTCEPGYAL-KDGE-CEDVDECAMGTHTCQPGFLCQNTKGS 787
Query: 61 YTCL----CEPGFAPTAAGYCADVDECAADSM-CKGG-RCVNSEGSFQC-----VCEAGY 109
+ C C GF G C D++EC + S C+ G C+N+ GS+ C +C GY
Sbjct: 788 FYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGY 847
Query: 110 RPTATRGACVDVDECEEQ-RVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW- 166
+ CVDV+ECE C G+ CHN PGS+RC+C GF GR C+ + W
Sbjct: 848 HASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWA 907
Query: 167 --GVSCQACPAQGSELYAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYR 221
G CQ Y C G + D+NEC A C C N+ Y+
Sbjct: 908 SPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA--QRCSQ-ECANIYGSYQ 964
Query: 222 CICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE-GTRHEPELQLCR 279
C C GY DG C DIDEC +C N GS+ C CPE G + C+
Sbjct: 965 CYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCK 1024
Query: 280 DIDECE------GETET-HYIESDYE--RGDIPPTFPTRTELASPCDNGRCINTHGGFEC 330
D+DEC E ET H I+ + R + PP + ++ + C+ C H EC
Sbjct: 1025 DVDECALGTHNCSEAETCHNIQGSFRCLRLECPPNYVQVSK--TKCERTTC---HDFLEC 1079
Query: 331 E 331
+
Sbjct: 1080 Q 1080
Score = 136 bits (328), Expect = 2e-31
Identities = 133/469 (28%), Positives = 177/469 (37%), Gaps = 85/469 (18%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C + +C N G + C C PG+ +G CR P + ++
Sbjct: 613 GELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGH-PPQPEAPQEPALKSEFSQVAS 670
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
P P + C + CK C GS C C GY A +C D++E
Sbjct: 671 NTIPLPLPQP-------NTCKDNGPCKQV-CSTVGGSAICSCFPGYAIMADGVSCEDINE 722
Query: 124 C-EEQRVCRNGR-CHNTPGSFRC----ECLPGFTLSNDGRTCLGLKLGWGV-SCQA---C 173
C + C G C NT GSF C C PG+ L DG + G +CQ C
Sbjct: 723 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGECEDVDECAMGTHTCQPGFLC 781
Query: 174 PAQGSELYAVL---CPEGPSKDNGG--ADINECTAVPGACPHG-SCENLEPGYRC----- 222
Y C +G +D G DINECT++ C G SC N Y C
Sbjct: 782 QNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 841
Query: 223 ICDPGYHPDADGL-CRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRD 280
IC GYH DG C D++EC+ C GQ C N GS+ C C G + + + C D
Sbjct: 842 ICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCID 901
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDA 340
++EC P R C + C NT G + C C G++L A
Sbjct: 902 VNECWAS-------------------PGRL-----CQH-TCENTLGSYRCSCASGFLLAA 936
Query: 341 TAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKG 400
+RC D R C + +C C G
Sbjct: 937 DGKRCEDVNECEAQR------CSQECANIYGSYQCYCRQGYQLAE--------------- 975
Query: 401 FAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCP-PGLTLDSTG 448
DG TC D+DECA A + C+N GSY+C CP G T+ + G
Sbjct: 976 ----DGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
Score = 111 bits (267), Expect = 5e-24
Identities = 115/432 (26%), Positives = 154/432 (35%), Gaps = 79/432 (18%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNS 97
D DEC P + C NT GSY C C PGF+ G + + S
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGR 157
E S Q P C D C++ C GS C C PG+ + DG
Sbjct: 664 EFS-QVASNTIPLPLPQPNTCKDNGPCKQV-------CSTVGGSAICSCFPGYAIMADGV 715
Query: 158 TCLGLK--------LGWGVSCQACPAQGSELYAVLCPEGPS-KDNGGADINECTAVPGAC 208
+C + G C A+ C G + KD D++EC C
Sbjct: 716 SCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTC 775
Query: 209 PHGS-CENLEPGYRCI----CDPGYHPDADGLCRDIDECDMHQSYCAGG-QCRNTAGSFT 262
G C+N + + C C G+ D +G C DI+EC C G C NT GS+T
Sbjct: 776 QPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYT 835
Query: 263 C-----VCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCD 317
C +C G + C D++ECE T H C
Sbjct: 836 CQRNPLICARGYHASDDGAKCVDVNECE--TGVHR-----------------------CG 870
Query: 318 NGR-CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECC 376
G+ C N G + C+C+ G+ DA + C+D CW C+ L C
Sbjct: 871 EGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE--CWASP-GRLCQHTCENTLGSYRCS 927
Query: 377 CSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRC 436
C+ G + DG C DV+EC A+ C+ C N GSY+C
Sbjct: 928 CASGFLLAA-------------------DGKRCEDVNEC--EAQRCSQ-ECANIYGSYQC 965
Query: 437 DCPPGLTLDSTG 448
C G L G
Sbjct: 966 YCRQGYQLAEDG 977
Score = 48.0 bits (109), Expect = 7e-05
Identities = 66/263 (25%), Positives = 88/263 (33%), Gaps = 41/263 (15%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQ 253
G D +EC +PG C N Y C C PG+ DG CR + H Q
Sbjct: 602 GDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRP----EGHPPQPEAPQ 657
Query: 254 CRNTAGSFTCVCPEGTRHE-PELQLCRDIDECEGETET---HYIESDYERGDIPPTFPTR 309
F+ V P+ C+D C+ T I S + I +
Sbjct: 658 EPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSC 717
Query: 310 TEL------ASPCDNG-RCINTHGGFEC----ECELGYVLDATAQRCLDNRRGSCWRRVV 358
++ C G C+NT G F C CE GY L
Sbjct: 718 EDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK------------------- 758
Query: 359 DGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALS 418
DG+CE E + C L + GF + C D++EC
Sbjct: 759 DGECE-DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSL 817
Query: 419 AELCAGG-TCVNTDGSYRCDCPP 440
+E C G +C+NT GSY C P
Sbjct: 818 SEPCRPGFSCINTVGSYTCQRNP 840
>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 177 bits (430), Expect = 9e-44
Identities = 138/466 (29%), Positives = 193/466 (41%), Gaps = 59/466 (12%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N C + G F+CIC PGYE G C + DEC +P + GRC + + C
Sbjct: 461 CQNDATCLDQIGEFQCICMPGYE----GVHCEVNTDECASSPCL-HNGRCLDKINEFQCE 515
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C GF Y DVDECA+ G +C++ ++ CVC GY T VD+DEC
Sbjct: 516 CPTGFTGHLCQY--DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE---VDIDEC 570
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
+ C G C + +F C C PG+T + C G +CQ Y
Sbjct: 571 DPD-PCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQ----DRDNAY 625
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCR-DID 240
C +G + N ++++C + P C G+C + GY C C+PGY +C +ID
Sbjct: 626 LCFCLKGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGY---TGSMCNINID 680
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERG 300
EC + + GG C + FTC CPEG H+P +++EC H D G
Sbjct: 681 ECAGNPCH-NGGTCEDGINGFTCRCPEG-YHDP--TCLSEVNECNSNPCVHGACRDSLNG 736
Query: 301 ---DIPPTFP-TRTEL------ASPCDN-GRCINTHGGFECECELGYV---LDATAQRCL 346
D P + T ++ ++PC N G C + G+ C C G+ C
Sbjct: 737 YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECA 796
Query: 347 DN---RRGSCWRRVVDGQCEAAAP------ELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
N +G+C V +C P E++L C G
Sbjct: 797 SNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAP--CAPSPCRNGGECRQSEDYESFS 854
Query: 398 XKGFAKLDGATCR-DVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
G TC D++EC LS C G +C NT G YRC C G
Sbjct: 855 CVCPTGWQGQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAG 898
Score = 132 bits (320), Expect = 2e-30
Identities = 129/461 (27%), Positives = 184/461 (39%), Gaps = 69/461 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + + C C G+ G C + +C ++ G C + S+TCL
Sbjct: 954 CRNGANCTDCVDSYTCTCPAGFS----GIHCENNTPDCTESS-CFNGGTCVDGINSFTCL 1008
Query: 65 CEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PGF YC DV+EC + GG C + GS++C C GY T C ++
Sbjct: 1009 CPPGFT---GSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY----TGPNCQNLVH 1061
Query: 124 CEEQRVCRNG-RCHNTPGSFRCECLPGFT-LSND--GRTCLGLKLGWGVS----CQ---A 172
+ C+NG +C T +RCEC G+T L D +C GV CQ
Sbjct: 1062 WCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGL 1121
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPD 231
C G+ + C G + ++EC+ P C +G+ C + GY C C GYH
Sbjct: 1122 CVDAGNTHHC-RCQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSCKCVAGYH-- 1176
Query: 232 ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
+IDEC H GG C + ++ C CP GT+ + ++D+C
Sbjct: 1177 GVNCSEEIDECLSHPCQ-NGGTCLDLPNTYKCSCPRGTQG---VHCEINVDDCN------ 1226
Query: 292 YIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECECELGYV---LDATAQRCLD 347
PP P + C +NG C++ GG+ C C G+V + CL
Sbjct: 1227 -----------PPVDPVSR--SPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLS 1273
Query: 348 N---RRG--SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF- 401
N RG +C +RV D CE A R E + +GF
Sbjct: 1274 NPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFI 1333
Query: 402 ----AKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A +GATC + S GGTC++ S C C
Sbjct: 1334 CKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLC 1374
Score = 132 bits (319), Expect = 2e-30
Identities = 128/466 (27%), Positives = 186/466 (39%), Gaps = 61/466 (13%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C++ D + C C G+ G C ++D+C +P C G C + Y C CEPG
Sbjct: 616 GTCQDRDNAYLCFCL----KGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPG 669
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR-PTATRGACVDVDECEEQ 127
+ + ++DECA + GG C + F C C GY PT +V+EC
Sbjct: 670 YTGSMCNI--NIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLS----EVNECNSN 723
Query: 128 RVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
C +G C ++ ++C+C PG++ +N + V+ C S Y C E
Sbjct: 724 P-CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSG-YVCTCRE 781
Query: 188 GPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQS 247
G S N +INEC + P G+C + GY+C C Y G ++ S
Sbjct: 782 GFSGPNCQTNINECASNP-CLNQGTCIDDVAGYKCNCLLPY----TGATCEVVLAPCAPS 836
Query: 248 YCA-GGQCRNTAG--SFTCVCPEGTR--------HEPELQLCRDIDECEGETETH--YIE 294
C GG+CR + SF+CVCP G + +E L CR C+ + + +
Sbjct: 837 PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQ 896
Query: 295 SDYE----RGDIPPTFPTRTELASPCDNG------RCINTHGGFECECELGYVLD----- 339
+ Y DI P C +G C+ G CE ++
Sbjct: 897 AGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRN 956
Query: 340 -ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX 398
A C+D+ +C CE P+ E C G G+
Sbjct: 957 GANCTDCVDSYTCTCPAGFSGIHCENNTPDCT---ESSCFNG---GTCVDGINSFTCLCP 1010
Query: 399 KGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
GF G+ C+ DV+EC S GGTC + GSYRC CP G T
Sbjct: 1011 PGFT---GSYCQHDVNECD-SQPCLHGGTCQDGCGSYRCTCPQGYT 1052
Score = 131 bits (317), Expect = 4e-30
Identities = 128/467 (27%), Positives = 187/467 (40%), Gaps = 56/467 (11%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA---GSYT 62
C +G C + F C C G G LC D C NP C G +T G
Sbjct: 344 CFHGATCHDRVASFYCECP----HGRTGLLCHLNDACISNP--CNEGSNCDTNPVNGKAI 397
Query: 63 CLCEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCVCEAGYRPTATRGAC-V 119
C C G+ A DVDEC+ + C+ G+C+N+ GSF+C C GY T C +
Sbjct: 398 CTCPSGYTGPACSQ--DVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEI 451
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
DV+EC + C + G F+C C+PG+ + + C + +E
Sbjct: 452 DVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINE 511
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
+ CP G + D++EC + P C +G+ C + Y C+C GY C
Sbjct: 512 -FQCECPTGFTGHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGY---TGTHCEV 565
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQL-------CRDIDECEGETE 289
DIDECD C G C++ +FTC+C G T H E + CR C+ + +
Sbjct: 566 DIDECDPDP--CHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQ-DRD 622
Query: 290 THYIESDYERGDIPPTFPTRTE--LASPCDNGRCINTHGGFECECELGY---VLDATAQR 344
Y+ +G P + +SPCD+G C++ G+EC CE GY + +
Sbjct: 623 NAYL-CFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDE 681
Query: 345 CLDN---RRGSCWRRVVDGQCEAAA----PELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
C N G+C + C P L C S G+
Sbjct: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDC 741
Query: 398 XKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLT 443
G++ G C D++ + C GGTC + Y C C G +
Sbjct: 742 DPGWS---GTNC-DINNNECESNPCVNGGTCKDMTSGYVCTCREGFS 784
Score = 127 bits (306), Expect = 9e-29
Identities = 128/467 (27%), Positives = 180/467 (38%), Gaps = 57/467 (12%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGSYTCL 64
C G CK+ F C+C+PGY G C +++EC P CR G C++ +Y C
Sbjct: 575 CHYGSCKDGVATFTCLCRPGYT----GHHCETNINECSSQP--CRHGGTCQDRDNAYLCF 628
Query: 65 CEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDVD 122
C G T C ++D+CA+ S C G C++ ++C CE GY T C +++D
Sbjct: 629 CLKG---TTGPNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGY----TGSMCNINID 680
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
EC G C + F C C G+ T ++ C G AC
Sbjct: 681 ECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHG----AC-RDSLN 735
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRD 238
Y C G S N + NEC + P C +G +C+++ GY C C G+ +
Sbjct: 736 GYKCDCDPGWSGTNCDINNNECESNP--CVNGGTCKDMTSGYVCTCREGF--SGPNCQTN 791
Query: 239 IDECDMHQSYCAGGQCRNTAG-SFTCVCP-EGTRHEPELQLCRDIDECEGETETHYIESD 296
I+EC + G + AG C+ P G E L C C E E D
Sbjct: 792 INECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP-SPCRNGGECRQSE-D 849
Query: 297 YERGD-IPPT--------FPTRTELASPCDNGR-CINTHGGFECECELGYV---LDATAQ 343
YE + PT + SPC +G C NTHGG+ C C+ GY +
Sbjct: 850 YESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDID 909
Query: 344 RCLDN---RRGSCWRRVVDGQCEA--AAPELLLRQEC--CCSVGLAWGSXXXXXXXXXXX 396
C N GSC + C+ ++ C S G+
Sbjct: 910 DCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTC 969
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
A G C + + GGTCV+ S+ C CPPG T
Sbjct: 970 TCP--AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT 1014
Score = 118 bits (285), Expect = 3e-26
Identities = 124/476 (26%), Positives = 184/476 (38%), Gaps = 61/476 (12%)
Query: 7 CTN-GICKNID----GGFECICKPGYESGSEGALC-RDVDE-CRDNPRVCRRGRCRN--T 57
C N G C +D + C C G+ G LC +D C NP CR G + T
Sbjct: 68 CKNAGTCHVVDRRGVADYACSCALGFS----GPLCLTPLDNACLTNP--CRNGGTCDLLT 121
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
Y C C PG++ + C D CA++ GG+C+ E S+ C C + R
Sbjct: 122 LTEYKCRCPPGWSGKS---CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCR-- 176
Query: 118 CVDVDEC-EEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPA 175
DV+EC ++ +CR+ G CHN GS+RC C T N R + + C
Sbjct: 177 -QDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRP 235
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPG-ACPH-GSCENLEPGYRCICDPGYHPDAD 233
G + C G + N +I++C PG C + G+C + Y C C P +
Sbjct: 236 TGDVTHECACLPGFTGQNCEENIDDC---PGNNCKNGGACVDGVNTYNCRCPPEW--TGQ 290
Query: 234 GLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEP--------ELQLCRDIDEC 284
D+DEC + + C GG C NT G + CVC G E C C
Sbjct: 291 YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATC 350
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT---HGGFECECELGYVLDAT 341
+ Y E + R + +++PC+ G +T +G C C GY A
Sbjct: 351 HDRVASFYCECPHGRTGLLCHLNDAC-ISNPCNEGSNCDTNPVNGKAICTCPSGYTGPAC 409
Query: 342 AQ---RCL-----DNRRGSCWRRVVDGQCEA----AAPELLLR-QECCCSVGLAWGSXXX 388
+Q C G C + +C+ P + EC + +
Sbjct: 410 SQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLD 469
Query: 389 XXXXXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ +G C + DECA S+ G C++ ++C+CP G T
Sbjct: 470 QIGEFQCICMPGY---EGVHCEVNTDECA-SSPCLHNGRCLDKINEFQCECPTGFT 521
Score = 118 bits (285), Expect = 3e-26
Identities = 124/485 (25%), Positives = 191/485 (39%), Gaps = 76/485 (15%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCRDV-DECRDNPRVCRRG-RCRNTAG--SY 61
C N G C + G++C C Y GA C V C +P CR G CR + S+
Sbjct: 800 CLNQGTCIDDVAGYKCNCLLPYT----GATCEVVLAPCAPSP--CRNGGECRQSEDYESF 853
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
+C+C G+ D++EC G C N+ G ++C C+AGY + R D+
Sbjct: 854 SCVCPTGWQGQTCE--VDINECVLSPCRHGASCQNTHGGYRCHCQAGY---SGRNCETDI 908
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
D+C G C + + C+CLPGF D C G +C C
Sbjct: 909 DDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDC----V 964
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
+ Y CP G S + + +CT +C + G+C + + C+C PG+ C+
Sbjct: 965 DSYTCTCPAGFSGIHCENNTPDCT--ESSCFNGGTCVDGINSFTCLCPPGF---TGSYCQ 1019
Query: 238 -DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR--------HEPELQLCRDIDECEGET 288
D++ECD Q GG C++ GS+ C CP+G H + C++ +C +T
Sbjct: 1020 HDVNECD-SQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC-WQT 1077
Query: 289 ETHYIESDYERG------DIPPTF------PTRTELASPCDN-GRCINTHGGFECECELG 335
T Y + G D+P ++A C + G C++ C C+ G
Sbjct: 1078 HTQY-RCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAG 1136
Query: 336 YV---LDATAQRCLDN--RRGSCWRRVVDG-QCEAAAPELLLR-----QECCCSVGLAWG 384
Y + C + + G+ + G C+ A + EC G
Sbjct: 1137 YTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGG 1196
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCR-DVDEC-------ALSAELCAGGTCVNTDGSYRC 436
+ +G G C +VD+C + S + GTCV+ G Y C
Sbjct: 1197 TCLDLPNTYKCSCPRG---TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC 1253
Query: 437 DCPPG 441
CPPG
Sbjct: 1254 TCPPG 1258
Score = 115 bits (277), Expect = 3e-25
Identities = 126/477 (26%), Positives = 185/477 (38%), Gaps = 76/477 (15%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGSYTCL 64
C +G C + G+EC C+PGY G++C ++DEC NP C G C + +TC
Sbjct: 650 CDSGTCLDKIDGYECACEPGYT----GSMCNINIDECAGNP--CHNGGTCEDGINGFTCR 703
Query: 65 CEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G+ PT ++V+EC ++ C G C +S ++C C+ G+ T ++ +E
Sbjct: 704 CPEGYHDPTCL---SEVNECNSNP-CVHGACRDSLNGYKCDCDPGWSGT---NCDINNNE 756
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSN--------------DGRTCLGLKLGWGVS 169
CE G C + + C C GF+ N + TC+ G+ +
Sbjct: 757 CESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 816
Query: 170 CQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
C P G+ VL P PS G EC E+ E + C+C G+
Sbjct: 817 C-LLPYTGATCEVVLAPCAPSPCRNGG---ECR---------QSEDYE-SFSCVCPTGWQ 862
Query: 230 PDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECE 285
+ DI+EC + S C G C+NT G + C C G E ++ CR
Sbjct: 863 GQTCEV--DINECVL--SPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHN 918
Query: 286 GETETHYIESDYERGDIPPTFPTR------TELAS-PCDNG-RCINTHGGFECECELGYV 337
G + T I + + D P F E AS PC NG C + + C C G+
Sbjct: 919 GGSCTDGINTAF--CDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFS 976
Query: 338 LDATAQRCLDNRRGSCWR--RVVDG------QCEAAAPELLLRQ---ECCCSVGLAWGSX 386
D SC+ VDG C + EC L G+
Sbjct: 977 GIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTC 1036
Query: 387 XXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G+ G C+++ S+ GG C T YRC+CP G T
Sbjct: 1037 QDGCGSYRCTCPQGYT---GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT 1090
Score = 108 bits (260), Expect = 3e-23
Identities = 130/457 (28%), Positives = 187/457 (40%), Gaps = 77/457 (16%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCL 64
C NG C N GG+ C+C G+ +G + + ++D+C C G C + S+ C
Sbjct: 306 CQNGGTCHNTHGGYNCVCVNGW-TGEDCS--ENIDDCAS--AACFHGATCHDRVASFYCE 360
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNS--EGSFQCVCEAGYRPTATRGACV-DV 121
C G C D C ++ +G C + G C C +GY T AC DV
Sbjct: 361 CPHG---RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY----TGPACSQDV 413
Query: 122 DECE-EQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS--CQ---ACP 174
DEC C + G+C NT GSF C+CL G+T G C + + VS CQ C
Sbjct: 414 DECSLGANPCEHAGKCINTLGSFECQCLQGYT----GPRC-EIDVNECVSNPCQNDATCL 468
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDAD 233
Q E + +C G + + +EC + P C H G C + ++C C G+
Sbjct: 469 DQIGE-FQCICMPGYEGVHCEVNTDECASSP--CLHNGRCLDKINEFQCECPTGF---TG 522
Query: 234 GLCR-DIDECDMHQSYCAGG-QCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECEGETET 290
LC+ D+DEC + C G +C + ++TCVC EG T E+ DIDEC+ +
Sbjct: 523 HLCQYDVDECA--STPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV----DIDECDPDP-C 575
Query: 291 HYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRR 350
HY G T T L P + G CE + + ++Q C
Sbjct: 576 HY-------GSCKDGVATFTCLCRP--------GYTGHHCETNIN---ECSSQPC--RHG 615
Query: 351 GSCWRRVVDGQC----EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
G+C R C P + + C S G+ G+ G
Sbjct: 616 GTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYT---G 672
Query: 407 ATCR-DVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
+ C ++DECA C GGTC + + C CP G
Sbjct: 673 SMCNINIDECA--GNPCHNGGTCEDGINGFTCRCPEG 707
Score = 106 bits (255), Expect = 1e-22
Identities = 129/478 (26%), Positives = 175/478 (36%), Gaps = 63/478 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N C +G C++ G++C C PG+ SG+ + + +EC NP V G C++ Y
Sbjct: 721 NSNPCVHGACRDSLNGYKCDCDPGW-SGTNCDI--NNNECESNPCV-NGGTCKDMTSGYV 776
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF + +++ECA++ G C++ ++C C Y T C V
Sbjct: 777 CTCREGF--SGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY----TGATCEVVL 830
Query: 123 ECEEQRVCRN-GRCHNTPG--SFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQ 176
CRN G C + SF C C G+ T D C+ G SCQ
Sbjct: 831 APCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQ--NTH 888
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL 235
G Y C G S N DI++C P C + GSC + C C PG+
Sbjct: 889 GG--YRCHCQAGYSGRNCETDIDDCR--PNPCHNGGSCTDGINTAFCDCLPGFR---GTF 941
Query: 236 C-RDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETETH 291
C DI+EC G C + S+TC CP G E C + G T
Sbjct: 942 CEEDINEC-ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD 1000
Query: 292 YIESDYERGDIPPTFPTR------TELAS-PC-DNGRCINTHGGFECECELGYV---LDA 340
I S PP F E S PC G C + G + C C GY
Sbjct: 1001 GINS--FTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQN 1058
Query: 341 TAQRCLDN---RRGSCWRRVVDGQCEAAA---------PEL---LLRQECCCSVGLAWGS 385
C + G CW+ +CE + P + + Q V
Sbjct: 1059 LVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQH 1118
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRD-VDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
+ A G+ C D VDEC+ S C G TC + G Y C C G
Sbjct: 1119 GGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAG 1174
Score = 102 bits (245), Expect = 2e-21
Identities = 118/445 (26%), Positives = 160/445 (35%), Gaps = 50/445 (11%)
Query: 34 ALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGG 92
AL C C G +C G+ C+C F C D + C + G
Sbjct: 16 ALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPR---CQDPNPCLSTPCKNAG 72
Query: 93 RC--VNSEG--SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN--TPGSFRCEC 146
C V+ G + C C G+ +D CRNG + T ++C C
Sbjct: 73 TCHVVDRRGVADYACSCALGFSGPL---CLTPLDNACLTNPCRNGGTCDLLTLTEYKCRC 129
Query: 147 LPGFTLSN--DGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAV 204
PG++ + C G C P + S Y CP D+NEC
Sbjct: 130 PPGWSGKSCQQADPCASNPCANGGQC--LPFEAS--YICHCPPSFHGPTCRQDVNECGQK 185
Query: 205 PGACPHG-SCENLEPGYRCICDPGYH-PDADGLCRDIDECDMHQSYCA-GGQCRNTAG-S 260
PG C HG +C N YRC+C + P+ + R C S C GG CR T +
Sbjct: 186 PGLCRHGGTCHNEVGSYRCVCRATHTGPNCE---RPYVPCS--PSPCQNGGTCRPTGDVT 240
Query: 261 FTCVCPEG-TRHEPELQL-------CRDIDECEGETETHYIESDYE-RGDIPPTFPTRTE 311
C C G T E + C++ C T+ E G +
Sbjct: 241 HECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ 300
Query: 312 LA-SPCDNG-RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWR------RVVDGQCE 363
L + C NG C NTHGG+ C C G+ + ++ D +C+ RV CE
Sbjct: 301 LMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCE 360
Query: 364 A--AAPELLLR-QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALSA 419
LL + C S GS + G C +DVDEC+L A
Sbjct: 361 CPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGA 420
Query: 420 ELCA-GGTCVNTDGSYRCDCPPGLT 443
C G C+NT GS+ C C G T
Sbjct: 421 NPCEHAGKCINTLGSFECQCLQGYT 445
Score = 97.5 bits (232), Expect = 9e-20
Identities = 97/367 (26%), Positives = 147/367 (40%), Gaps = 53/367 (14%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSY 61
NGG C +GI F C+C PG+ G+ C+ DV+EC P G C++ GSY
Sbjct: 994 NGGTCVDGI-----NSFTCLCPPGF----TGSYCQHDVNECDSQP-CLHGGTCQDGCGSY 1043
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYR------PTAT 114
C C G+ C ++ S CK GG+C + ++C C +G+ P+ +
Sbjct: 1044 RCTCPQGY---TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVS 1100
Query: 115 RGACVDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQA 172
+ R+C++ G C + + C C G+T G C L S CQ
Sbjct: 1101 CEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQN 1156
Query: 173 CPAQGSEL--YAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCIC---DP 226
L Y+ C G N +I+EC + P C + G+C +L Y+C C
Sbjct: 1157 GATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQ 1214
Query: 227 GYHPD--ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDI 281
G H + D +D G C + G ++C CP G R E ++ C
Sbjct: 1215 GVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLS- 1273
Query: 282 DECEGETETHYIE--SDYERGDIPPTFPTRTE------LASPCDN-GRCI---NTHGGFE 329
+ C+ + ++ +D+ R E PC N G C NT GF
Sbjct: 1274 NPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFI 1333
Query: 330 CECELGY 336
C+C G+
Sbjct: 1334 CKCPAGF 1340
Score = 81.8 bits (193), Expect = 5e-15
Identities = 80/286 (27%), Positives = 116/286 (40%), Gaps = 43/286 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRD-------NPRVCRRGRCRNT 57
C NG C ++ ++C C G++G C +VD+C +P+ G C +
Sbjct: 1192 CQNGGTCLDLPNTYKCSCP----RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQ 1247
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGG--RCVNSEGSFQCVCEAGYRPTATR 115
G Y+C C PGF DV+EC ++ G CV F C C AG+ T R
Sbjct: 1248 VGGYSCTCPPGFVGERCE--GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH--TGRR 1303
Query: 116 GACVDVDECEEQRVCRNGRC---HNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVS 169
V ++ C+ + G C NT F C+C GF T ND RTC L+ G +
Sbjct: 1304 CESV-INGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGT 1362
Query: 170 CQACPAQGSELYAVLCP-EGPSKDNGGADINECTAVPGACPHGSCE--NLEPGYRCICDP 226
C + P S L P GP + + C G+CE + P YRC+C
Sbjct: 1363 CISGPR--SPTCLCLGPFTGPECQFPAS--SPCLGGNPCYNQGTCEPTSESPFYRCLCPA 1418
Query: 227 GY---------HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
+ + G RDI + + C +C+ AG+ C
Sbjct: 1419 KFNGLLCHILDYSFGGGAGRDIPP-PLIEEACELPECQEDAGNKVC 1463
>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 177 bits (430), Expect = 9e-44
Identities = 138/466 (29%), Positives = 193/466 (41%), Gaps = 59/466 (12%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N C + G F+CIC PGYE G C + DEC +P + GRC + + C
Sbjct: 461 CQNDATCLDQIGEFQCICMPGYE----GVHCEVNTDECASSPCL-HNGRCLDKINEFQCE 515
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C GF Y DVDECA+ G +C++ ++ CVC GY T VD+DEC
Sbjct: 516 CPTGFTGHLCQY--DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE---VDIDEC 570
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
+ C G C + +F C C PG+T + C G +CQ Y
Sbjct: 571 DPD-PCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQ----DRDNAY 625
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCR-DID 240
C +G + N ++++C + P C G+C + GY C C+PGY +C +ID
Sbjct: 626 LCFCLKGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGY---TGSMCNINID 680
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERG 300
EC + + GG C + FTC CPEG H+P +++EC H D G
Sbjct: 681 ECAGNPCH-NGGTCEDGINGFTCRCPEG-YHDP--TCLSEVNECNSNPCVHGACRDSLNG 736
Query: 301 ---DIPPTFP-TRTEL------ASPCDN-GRCINTHGGFECECELGYV---LDATAQRCL 346
D P + T ++ ++PC N G C + G+ C C G+ C
Sbjct: 737 YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECA 796
Query: 347 DN---RRGSCWRRVVDGQCEAAAP------ELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
N +G+C V +C P E++L C G
Sbjct: 797 SNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAP--CAPSPCRNGGECRQSEDYESFS 854
Query: 398 XKGFAKLDGATCR-DVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
G TC D++EC LS C G +C NT G YRC C G
Sbjct: 855 CVCPTGWQGQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAG 898
Score = 132 bits (320), Expect = 2e-30
Identities = 129/461 (27%), Positives = 184/461 (39%), Gaps = 69/461 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + + C C G+ G C + +C ++ G C + S+TCL
Sbjct: 954 CRNGANCTDCVDSYTCTCPAGFS----GIHCENNTPDCTESS-CFNGGTCVDGINSFTCL 1008
Query: 65 CEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PGF YC DV+EC + GG C + GS++C C GY T C ++
Sbjct: 1009 CPPGFT---GSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY----TGPNCQNLVH 1061
Query: 124 CEEQRVCRNG-RCHNTPGSFRCECLPGFT-LSND--GRTCLGLKLGWGVS----CQ---A 172
+ C+NG +C T +RCEC G+T L D +C GV CQ
Sbjct: 1062 WCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGL 1121
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPD 231
C G+ + C G + ++EC+ P C +G+ C + GY C C GYH
Sbjct: 1122 CVDAGNTHHC-RCQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSCKCVAGYH-- 1176
Query: 232 ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
+IDEC H GG C + ++ C CP GT+ + ++D+C
Sbjct: 1177 GVNCSEEIDECLSHPCQ-NGGTCLDLPNTYKCSCPRGTQG---VHCEINVDDCN------ 1226
Query: 292 YIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECECELGYV---LDATAQRCLD 347
PP P + C +NG C++ GG+ C C G+V + CL
Sbjct: 1227 -----------PPVDPVSR--SPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLS 1273
Query: 348 N---RRG--SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF- 401
N RG +C +RV D CE A R E + +GF
Sbjct: 1274 NPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFI 1333
Query: 402 ----AKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A +GATC + S GGTC++ S C C
Sbjct: 1334 CKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLC 1374
Score = 132 bits (319), Expect = 2e-30
Identities = 128/466 (27%), Positives = 186/466 (39%), Gaps = 61/466 (13%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C++ D + C C G+ G C ++D+C +P C G C + Y C CEPG
Sbjct: 616 GTCQDRDNAYLCFCL----KGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPG 669
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR-PTATRGACVDVDECEEQ 127
+ + ++DECA + GG C + F C C GY PT +V+EC
Sbjct: 670 YTGSMCNI--NIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLS----EVNECNSN 723
Query: 128 RVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
C +G C ++ ++C+C PG++ +N + V+ C S Y C E
Sbjct: 724 P-CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSG-YVCTCRE 781
Query: 188 GPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQS 247
G S N +INEC + P G+C + GY+C C Y G ++ S
Sbjct: 782 GFSGPNCQTNINECASNP-CLNQGTCIDDVAGYKCNCLLPY----TGATCEVVLAPCAPS 836
Query: 248 YCA-GGQCRNTAG--SFTCVCPEGTR--------HEPELQLCRDIDECEGETETH--YIE 294
C GG+CR + SF+CVCP G + +E L CR C+ + + +
Sbjct: 837 PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQ 896
Query: 295 SDYE----RGDIPPTFPTRTELASPCDNG------RCINTHGGFECECELGYVLD----- 339
+ Y DI P C +G C+ G CE ++
Sbjct: 897 AGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRN 956
Query: 340 -ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX 398
A C+D+ +C CE P+ E C G G+
Sbjct: 957 GANCTDCVDSYTCTCPAGFSGIHCENNTPDCT---ESSCFNG---GTCVDGINSFTCLCP 1010
Query: 399 KGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
GF G+ C+ DV+EC S GGTC + GSYRC CP G T
Sbjct: 1011 PGFT---GSYCQHDVNECD-SQPCLHGGTCQDGCGSYRCTCPQGYT 1052
Score = 131 bits (317), Expect = 4e-30
Identities = 128/467 (27%), Positives = 187/467 (40%), Gaps = 56/467 (11%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA---GSYT 62
C +G C + F C C G G LC D C NP C G +T G
Sbjct: 344 CFHGATCHDRVASFYCECP----HGRTGLLCHLNDACISNP--CNEGSNCDTNPVNGKAI 397
Query: 63 CLCEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCVCEAGYRPTATRGAC-V 119
C C G+ A DVDEC+ + C+ G+C+N+ GSF+C C GY T C +
Sbjct: 398 CTCPSGYTGPACSQ--DVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEI 451
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
DV+EC + C + G F+C C+PG+ + + C + +E
Sbjct: 452 DVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINE 511
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
+ CP G + D++EC + P C +G+ C + Y C+C GY C
Sbjct: 512 -FQCECPTGFTGHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGY---TGTHCEV 565
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQL-------CRDIDECEGETE 289
DIDECD C G C++ +FTC+C G T H E + CR C+ + +
Sbjct: 566 DIDECDPDP--CHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQ-DRD 622
Query: 290 THYIESDYERGDIPPTFPTRTE--LASPCDNGRCINTHGGFECECELGY---VLDATAQR 344
Y+ +G P + +SPCD+G C++ G+EC CE GY + +
Sbjct: 623 NAYL-CFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDE 681
Query: 345 CLDN---RRGSCWRRVVDGQCEAAA----PELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
C N G+C + C P L C S G+
Sbjct: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDC 741
Query: 398 XKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLT 443
G++ G C D++ + C GGTC + Y C C G +
Sbjct: 742 DPGWS---GTNC-DINNNECESNPCVNGGTCKDMTSGYVCTCREGFS 784
Score = 127 bits (306), Expect = 9e-29
Identities = 128/467 (27%), Positives = 180/467 (38%), Gaps = 57/467 (12%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGSYTCL 64
C G CK+ F C+C+PGY G C +++EC P CR G C++ +Y C
Sbjct: 575 CHYGSCKDGVATFTCLCRPGYT----GHHCETNINECSSQP--CRHGGTCQDRDNAYLCF 628
Query: 65 CEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDVD 122
C G T C ++D+CA+ S C G C++ ++C CE GY T C +++D
Sbjct: 629 CLKG---TTGPNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGY----TGSMCNINID 680
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
EC G C + F C C G+ T ++ C G AC
Sbjct: 681 ECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHG----AC-RDSLN 735
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRD 238
Y C G S N + NEC + P C +G +C+++ GY C C G+ +
Sbjct: 736 GYKCDCDPGWSGTNCDINNNECESNP--CVNGGTCKDMTSGYVCTCREGF--SGPNCQTN 791
Query: 239 IDECDMHQSYCAGGQCRNTAG-SFTCVCP-EGTRHEPELQLCRDIDECEGETETHYIESD 296
I+EC + G + AG C+ P G E L C C E E D
Sbjct: 792 INECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP-SPCRNGGECRQSE-D 849
Query: 297 YERGD-IPPT--------FPTRTELASPCDNGR-CINTHGGFECECELGYV---LDATAQ 343
YE + PT + SPC +G C NTHGG+ C C+ GY +
Sbjct: 850 YESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDID 909
Query: 344 RCLDN---RRGSCWRRVVDGQCEA--AAPELLLRQEC--CCSVGLAWGSXXXXXXXXXXX 396
C N GSC + C+ ++ C S G+
Sbjct: 910 DCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTC 969
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
A G C + + GGTCV+ S+ C CPPG T
Sbjct: 970 TCP--AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT 1014
Score = 118 bits (285), Expect = 3e-26
Identities = 124/476 (26%), Positives = 184/476 (38%), Gaps = 61/476 (12%)
Query: 7 CTN-GICKNID----GGFECICKPGYESGSEGALC-RDVDE-CRDNPRVCRRGRCRN--T 57
C N G C +D + C C G+ G LC +D C NP CR G + T
Sbjct: 68 CKNAGTCHVVDRRGVADYACSCALGFS----GPLCLTPLDNACLTNP--CRNGGTCDLLT 121
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
Y C C PG++ + C D CA++ GG+C+ E S+ C C + R
Sbjct: 122 LTEYKCRCPPGWSGKS---CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCR-- 176
Query: 118 CVDVDEC-EEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPA 175
DV+EC ++ +CR+ G CHN GS+RC C T N R + + C
Sbjct: 177 -QDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRP 235
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPG-ACPH-GSCENLEPGYRCICDPGYHPDAD 233
G + C G + N +I++C PG C + G+C + Y C C P +
Sbjct: 236 TGDVTHECACLPGFTGQNCEENIDDC---PGNNCKNGGACVDGVNTYNCRCPPEW--TGQ 290
Query: 234 GLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEP--------ELQLCRDIDEC 284
D+DEC + + C GG C NT G + CVC G E C C
Sbjct: 291 YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATC 350
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT---HGGFECECELGYVLDAT 341
+ Y E + R + +++PC+ G +T +G C C GY A
Sbjct: 351 HDRVASFYCECPHGRTGLLCHLNDAC-ISNPCNEGSNCDTNPVNGKAICTCPSGYTGPAC 409
Query: 342 AQ---RCL-----DNRRGSCWRRVVDGQCEA----AAPELLLR-QECCCSVGLAWGSXXX 388
+Q C G C + +C+ P + EC + +
Sbjct: 410 SQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLD 469
Query: 389 XXXXXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ +G C + DECA S+ G C++ ++C+CP G T
Sbjct: 470 QIGEFQCICMPGY---EGVHCEVNTDECA-SSPCLHNGRCLDKINEFQCECPTGFT 521
Score = 118 bits (285), Expect = 3e-26
Identities = 124/485 (25%), Positives = 191/485 (39%), Gaps = 76/485 (15%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCRDV-DECRDNPRVCRRG-RCRNTAG--SY 61
C N G C + G++C C Y GA C V C +P CR G CR + S+
Sbjct: 800 CLNQGTCIDDVAGYKCNCLLPYT----GATCEVVLAPCAPSP--CRNGGECRQSEDYESF 853
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
+C+C G+ D++EC G C N+ G ++C C+AGY + R D+
Sbjct: 854 SCVCPTGWQGQTCE--VDINECVLSPCRHGASCQNTHGGYRCHCQAGY---SGRNCETDI 908
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
D+C G C + + C+CLPGF D C G +C C
Sbjct: 909 DDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDC----V 964
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
+ Y CP G S + + +CT +C + G+C + + C+C PG+ C+
Sbjct: 965 DSYTCTCPAGFSGIHCENNTPDCT--ESSCFNGGTCVDGINSFTCLCPPGF---TGSYCQ 1019
Query: 238 -DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR--------HEPELQLCRDIDECEGET 288
D++ECD Q GG C++ GS+ C CP+G H + C++ +C +T
Sbjct: 1020 HDVNECD-SQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC-WQT 1077
Query: 289 ETHYIESDYERG------DIPPTF------PTRTELASPCDN-GRCINTHGGFECECELG 335
T Y + G D+P ++A C + G C++ C C+ G
Sbjct: 1078 HTQY-RCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAG 1136
Query: 336 YV---LDATAQRCLDN--RRGSCWRRVVDG-QCEAAAPELLLR-----QECCCSVGLAWG 384
Y + C + + G+ + G C+ A + EC G
Sbjct: 1137 YTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGG 1196
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCR-DVDEC-------ALSAELCAGGTCVNTDGSYRC 436
+ +G G C +VD+C + S + GTCV+ G Y C
Sbjct: 1197 TCLDLPNTYKCSCPRG---TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC 1253
Query: 437 DCPPG 441
CPPG
Sbjct: 1254 TCPPG 1258
Score = 115 bits (277), Expect = 3e-25
Identities = 126/477 (26%), Positives = 185/477 (38%), Gaps = 76/477 (15%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGSYTCL 64
C +G C + G+EC C+PGY G++C ++DEC NP C G C + +TC
Sbjct: 650 CDSGTCLDKIDGYECACEPGYT----GSMCNINIDECAGNP--CHNGGTCEDGINGFTCR 703
Query: 65 CEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G+ PT ++V+EC ++ C G C +S ++C C+ G+ T ++ +E
Sbjct: 704 CPEGYHDPTCL---SEVNECNSNP-CVHGACRDSLNGYKCDCDPGWSGT---NCDINNNE 756
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSN--------------DGRTCLGLKLGWGVS 169
CE G C + + C C GF+ N + TC+ G+ +
Sbjct: 757 CESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 816
Query: 170 CQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
C P G+ VL P PS G EC E+ E + C+C G+
Sbjct: 817 C-LLPYTGATCEVVLAPCAPSPCRNGG---ECR---------QSEDYE-SFSCVCPTGWQ 862
Query: 230 PDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECE 285
+ DI+EC + S C G C+NT G + C C G E ++ CR
Sbjct: 863 GQTCEV--DINECVL--SPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHN 918
Query: 286 GETETHYIESDYERGDIPPTFPTR------TELAS-PCDNG-RCINTHGGFECECELGYV 337
G + T I + + D P F E AS PC NG C + + C C G+
Sbjct: 919 GGSCTDGINTAF--CDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFS 976
Query: 338 LDATAQRCLDNRRGSCWR--RVVDG------QCEAAAPELLLRQ---ECCCSVGLAWGSX 386
D SC+ VDG C + EC L G+
Sbjct: 977 GIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTC 1036
Query: 387 XXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G+ G C+++ S+ GG C T YRC+CP G T
Sbjct: 1037 QDGCGSYRCTCPQGYT---GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT 1090
Score = 108 bits (260), Expect = 3e-23
Identities = 130/457 (28%), Positives = 187/457 (40%), Gaps = 77/457 (16%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCL 64
C NG C N GG+ C+C G+ +G + + ++D+C C G C + S+ C
Sbjct: 306 CQNGGTCHNTHGGYNCVCVNGW-TGEDCS--ENIDDCAS--AACFHGATCHDRVASFYCE 360
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNS--EGSFQCVCEAGYRPTATRGACV-DV 121
C G C D C ++ +G C + G C C +GY T AC DV
Sbjct: 361 CPHG---RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY----TGPACSQDV 413
Query: 122 DECE-EQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS--CQ---ACP 174
DEC C + G+C NT GSF C+CL G+T G C + + VS CQ C
Sbjct: 414 DECSLGANPCEHAGKCINTLGSFECQCLQGYT----GPRC-EIDVNECVSNPCQNDATCL 468
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDAD 233
Q E + +C G + + +EC + P C H G C + ++C C G+
Sbjct: 469 DQIGE-FQCICMPGYEGVHCEVNTDECASSP--CLHNGRCLDKINEFQCECPTGF---TG 522
Query: 234 GLCR-DIDECDMHQSYCAGG-QCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECEGETET 290
LC+ D+DEC + C G +C + ++TCVC EG T E+ DIDEC+ +
Sbjct: 523 HLCQYDVDECA--STPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV----DIDECDPDP-C 575
Query: 291 HYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRR 350
HY G T T L P + G CE + + ++Q C
Sbjct: 576 HY-------GSCKDGVATFTCLCRP--------GYTGHHCETNIN---ECSSQPC--RHG 615
Query: 351 GSCWRRVVDGQC----EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
G+C R C P + + C S G+ G+ G
Sbjct: 616 GTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYT---G 672
Query: 407 ATCR-DVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
+ C ++DECA C GGTC + + C CP G
Sbjct: 673 SMCNINIDECA--GNPCHNGGTCEDGINGFTCRCPEG 707
Score = 106 bits (255), Expect = 1e-22
Identities = 129/478 (26%), Positives = 175/478 (36%), Gaps = 63/478 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N C +G C++ G++C C PG+ SG+ + + +EC NP V G C++ Y
Sbjct: 721 NSNPCVHGACRDSLNGYKCDCDPGW-SGTNCDI--NNNECESNPCV-NGGTCKDMTSGYV 776
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF + +++ECA++ G C++ ++C C Y T C V
Sbjct: 777 CTCREGF--SGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY----TGATCEVVL 830
Query: 123 ECEEQRVCRN-GRCHNTPG--SFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQ 176
CRN G C + SF C C G+ T D C+ G SCQ
Sbjct: 831 APCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQ--NTH 888
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL 235
G Y C G S N DI++C P C + GSC + C C PG+
Sbjct: 889 GG--YRCHCQAGYSGRNCETDIDDCR--PNPCHNGGSCTDGINTAFCDCLPGFR---GTF 941
Query: 236 C-RDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETETH 291
C DI+EC G C + S+TC CP G E C + G T
Sbjct: 942 CEEDINEC-ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD 1000
Query: 292 YIESDYERGDIPPTFPTR------TELAS-PC-DNGRCINTHGGFECECELGYV---LDA 340
I S PP F E S PC G C + G + C C GY
Sbjct: 1001 GINS--FTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQN 1058
Query: 341 TAQRCLDN---RRGSCWRRVVDGQCEAAA---------PEL---LLRQECCCSVGLAWGS 385
C + G CW+ +CE + P + + Q V
Sbjct: 1059 LVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQH 1118
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRD-VDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
+ A G+ C D VDEC+ S C G TC + G Y C C G
Sbjct: 1119 GGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAG 1174
Score = 102 bits (245), Expect = 2e-21
Identities = 118/445 (26%), Positives = 160/445 (35%), Gaps = 50/445 (11%)
Query: 34 ALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGG 92
AL C C G +C G+ C+C F C D + C + G
Sbjct: 16 ALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPR---CQDPNPCLSTPCKNAG 72
Query: 93 RC--VNSEG--SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN--TPGSFRCEC 146
C V+ G + C C G+ +D CRNG + T ++C C
Sbjct: 73 TCHVVDRRGVADYACSCALGFSGPL---CLTPLDNACLTNPCRNGGTCDLLTLTEYKCRC 129
Query: 147 LPGFTLSN--DGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAV 204
PG++ + C G C P + S Y CP D+NEC
Sbjct: 130 PPGWSGKSCQQADPCASNPCANGGQC--LPFEAS--YICHCPPSFHGPTCRQDVNECGQK 185
Query: 205 PGACPHG-SCENLEPGYRCICDPGYH-PDADGLCRDIDECDMHQSYCA-GGQCRNTAG-S 260
PG C HG +C N YRC+C + P+ + R C S C GG CR T +
Sbjct: 186 PGLCRHGGTCHNEVGSYRCVCRATHTGPNCE---RPYVPCS--PSPCQNGGTCRPTGDVT 240
Query: 261 FTCVCPEG-TRHEPELQL-------CRDIDECEGETETHYIESDYE-RGDIPPTFPTRTE 311
C C G T E + C++ C T+ E G +
Sbjct: 241 HECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ 300
Query: 312 LA-SPCDNG-RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWR------RVVDGQCE 363
L + C NG C NTHGG+ C C G+ + ++ D +C+ RV CE
Sbjct: 301 LMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCE 360
Query: 364 A--AAPELLLR-QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALSA 419
LL + C S GS + G C +DVDEC+L A
Sbjct: 361 CPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGA 420
Query: 420 ELCA-GGTCVNTDGSYRCDCPPGLT 443
C G C+NT GS+ C C G T
Sbjct: 421 NPCEHAGKCINTLGSFECQCLQGYT 445
Score = 97.5 bits (232), Expect = 9e-20
Identities = 97/367 (26%), Positives = 147/367 (40%), Gaps = 53/367 (14%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSY 61
NGG C +GI F C+C PG+ G+ C+ DV+EC P G C++ GSY
Sbjct: 994 NGGTCVDGI-----NSFTCLCPPGF----TGSYCQHDVNECDSQP-CLHGGTCQDGCGSY 1043
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYR------PTAT 114
C C G+ C ++ S CK GG+C + ++C C +G+ P+ +
Sbjct: 1044 RCTCPQGY---TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVS 1100
Query: 115 RGACVDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQA 172
+ R+C++ G C + + C C G+T G C L S CQ
Sbjct: 1101 CEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQN 1156
Query: 173 CPAQGSEL--YAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCIC---DP 226
L Y+ C G N +I+EC + P C + G+C +L Y+C C
Sbjct: 1157 GATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQ 1214
Query: 227 GYHPD--ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDI 281
G H + D +D G C + G ++C CP G R E ++ C
Sbjct: 1215 GVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLS- 1273
Query: 282 DECEGETETHYIE--SDYERGDIPPTFPTRTE------LASPCDN-GRCI---NTHGGFE 329
+ C+ + ++ +D+ R E PC N G C NT GF
Sbjct: 1274 NPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFI 1333
Query: 330 CECELGY 336
C+C G+
Sbjct: 1334 CKCPAGF 1340
Score = 81.8 bits (193), Expect = 5e-15
Identities = 80/286 (27%), Positives = 116/286 (40%), Gaps = 43/286 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRD-------NPRVCRRGRCRNT 57
C NG C ++ ++C C G++G C +VD+C +P+ G C +
Sbjct: 1192 CQNGGTCLDLPNTYKCSCP----RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQ 1247
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGG--RCVNSEGSFQCVCEAGYRPTATR 115
G Y+C C PGF DV+EC ++ G CV F C C AG+ T R
Sbjct: 1248 VGGYSCTCPPGFVGERCE--GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH--TGRR 1303
Query: 116 GACVDVDECEEQRVCRNGRC---HNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVS 169
V ++ C+ + G C NT F C+C GF T ND RTC L+ G +
Sbjct: 1304 CESV-INGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGT 1362
Query: 170 CQACPAQGSELYAVLCP-EGPSKDNGGADINECTAVPGACPHGSCE--NLEPGYRCICDP 226
C + P S L P GP + + C G+CE + P YRC+C
Sbjct: 1363 CISGPR--SPTCLCLGPFTGPECQFPAS--SPCLGGNPCYNQGTCEPTSESPFYRCLCPA 1418
Query: 227 GY---------HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
+ + G RDI + + C +C+ AG+ C
Sbjct: 1419 KFNGLLCHILDYSFGGGAGRDIPP-PLIEEACELPECQEDAGNKVC 1463
>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
Length = 2444
Score = 176 bits (428), Expect = 2e-43
Identities = 141/468 (30%), Positives = 197/468 (42%), Gaps = 62/468 (13%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N C + G F+C+C PGYE G C + DEC +P + GRC + + C
Sbjct: 461 CQNDATCLDQIGEFQCMCMPGYE----GVHCEVNTDECASSPCL-HNGRCLDKINEFQCE 515
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C GF Y DVDECA+ G +C++ ++ CVC GY T VD+DEC
Sbjct: 516 CPTGFTGHLCQY--DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE---VDIDEC 570
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-----E 179
+ C G C + +F C C PG+T G C + S Q C +G+
Sbjct: 571 DPD-PCHYGSCKDGVATFTCLCRPGYT----GHHC-ETNIN-ECSSQPCRLRGTCQDPDN 623
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCR-D 238
Y C +G + N ++++C + P C G+C + GY C C+PGY +C +
Sbjct: 624 AYLCFCLKGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGY---TGSMCNSN 678
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
IDEC + + GG C + FTC CPEG H+P +++EC H D
Sbjct: 679 IDECAGNPCH-NGGTCEDGINGFTCRCPEG-YHDP--TCLSEVNECNSNPCVHGACRDSL 734
Query: 299 RG---DIPPTFP-TRTEL------ASPCDN-GRCINTHGGFECECELGYV---LDATAQR 344
G D P + T ++ ++PC N G C + G C C G+
Sbjct: 735 NGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINE 794
Query: 345 CLDN---RRGSCWRRVVDGQCEAAAP------ELLLRQECCCSVGLAWGSXXXXXXXXXX 395
C N +G+C V +C P E++L C S G
Sbjct: 795 CASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVL-APCAPSPCRNGGECRQSEDYESF 853
Query: 396 XXXKGFAKLDGATCR-DVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
A G TC D++EC LS C G +C NT G YRC C G
Sbjct: 854 SCVCPTAGAKGQTCEVDINECVLSP--CRHGASCQNTHGXYRCHCQAG 899
Score = 128 bits (310), Expect = 3e-29
Identities = 127/467 (27%), Positives = 187/467 (40%), Gaps = 56/467 (11%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA---GSYT 62
C +G C + F C C G G LC D C NP C G +T G
Sbjct: 344 CFHGATCHDRVASFYCECP----HGRTGLLCHLNDACISNP--CNEGSNCDTNPVNGKAI 397
Query: 63 CLCEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCVCEAGYRPTATRGAC-V 119
C C G+ A DVDEC+ + C+ G+C+N+ GSF+C C GY T C +
Sbjct: 398 CTCPSGYTGPACSQ--DVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEI 451
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
DV+EC + C + G F+C C+PG+ + + C + +E
Sbjct: 452 DVNECVSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECASSPCLHNGRCLDKINE 511
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
+ CP G + D++EC + P C +G+ C + Y C+C GY C
Sbjct: 512 -FQCECPTGFTGHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGY---TGTHCEV 565
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQL-------CRDIDECEGETE 289
DIDECD C G C++ +FTC+C G T H E + CR C+ + +
Sbjct: 566 DIDECDPDP--CHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRLRGTCQ-DPD 622
Query: 290 THYIESDYERGDIPPTFPTRTE--LASPCDNGRCINTHGGFECECELGY---VLDATAQR 344
Y+ +G P + +SPCD+G C++ G+EC CE GY + ++
Sbjct: 623 NAYL-CFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNSNIDE 681
Query: 345 CLDN---RRGSCWRRVVDGQCEAAA----PELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
C N G+C + C P L C S G+
Sbjct: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDC 741
Query: 398 XKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLT 443
G++ G C D++ + C GGTC + C C G +
Sbjct: 742 DPGWS---GTNC-DINNNECESNPCVNGGTCKDMTSGIVCTCREGFS 784
Score = 126 bits (304), Expect = 2e-28
Identities = 127/461 (27%), Positives = 181/461 (39%), Gaps = 69/461 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + + C C G+ G C + +C ++ G C + S+TCL
Sbjct: 955 CRNGANCTDCVDSYTCTCPAGFS----GIHCENNTPDCTESS-CFNGGTCVDGINSFTCL 1009
Query: 65 CEPGFAPTAAGYCADV-DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PGF YC V +EC + GG C + G +C C GY T C ++
Sbjct: 1010 CPPGFT---GSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGY----TGPNCQNLVH 1062
Query: 124 CEEQRVCRNG-RCHNTPGSFRCECLPGFT-LSND--GRTCLGLKLGWGVS----CQ---A 172
+ C+NG +C T +RCEC G+T L D +C GV CQ
Sbjct: 1063 WCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGL 1122
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPD 231
C G+ + C G + ++EC+ P C +G+ C + GY C C GYH
Sbjct: 1123 CVDAGNTHHC-RCQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSCKCVAGYH-- 1177
Query: 232 ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
+IDEC H GG C + ++ C CP GT+ + ++D+C
Sbjct: 1178 GVNCSEEIDECLSHPCQ-NGGTCLDLPNTYKCSCPRGTQG---VHCEINVDDCN------ 1227
Query: 292 YIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECECELGYV---LDATAQRCLD 347
PP P + C +NG C++ GG+ C C G+V + CL
Sbjct: 1228 -----------PPVDPVSR--SPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLS 1274
Query: 348 N---RRG--SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF- 401
N RG +C +RV D CE A R E + +GF
Sbjct: 1275 NPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFI 1334
Query: 402 ----AKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A +GATC + S GGTC++ S C C
Sbjct: 1335 CKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLC 1375
Score = 125 bits (302), Expect = 3e-28
Identities = 124/460 (26%), Positives = 183/460 (39%), Gaps = 76/460 (16%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C +GI GF C C GY + +V+EC NP C G CR++ Y
Sbjct: 689 NGGTCEDGI-----NGFTCRCPEGYH---DPTCLSEVNECNSNP--CVHGACRDSLNGYK 738
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C+PG++ T + +EC ++ GG C + C C G+ + +++
Sbjct: 739 CDCDPGWSGTNCDI--NNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQ---TNIN 793
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQ---AC-PAQG 177
EC G C + ++C CL +T G TC + S C+ C ++
Sbjct: 794 ECASNPCLNKGTCIDDVAGYKCNCLLPYT----GATCEVVLAPCAPSPCRNGGECRQSED 849
Query: 178 SELYAVLCPEGPSKDNG-GADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGL 235
E ++ +CP +K DINEC P C HG SC+N YRC C GY
Sbjct: 850 YESFSCVCPTAGAKGQTCEVDINECVLSP--CRHGASCQNTHGXYRCHCQAGY--SGRNC 905
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH---EPELQLCRDIDECE-GETETH 291
DID+C + + GG C + + C C G R E ++ C D C G T
Sbjct: 906 ETDIDDCRPNPCH-NGGSCTDGINTAFCDCLPGFRGTFCEEDINECAS-DPCRNGANCTD 963
Query: 292 YIES-------DYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLDATAQ 343
++S + P TE S C NG C++ F C C G+
Sbjct: 964 CVDSYTCTCPAGFSGIHCENNTPDCTE--SSCFNGGTCVDGINSFTCLCPPGFT------ 1015
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
GS + VV+ +C++ C +G G+ +G+
Sbjct: 1016 -------GSYCQHVVN-ECDSRP----------CLLG---GTCQDGRGLHRCTCPQGYT- 1053
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G C+++ S+ GG C T YRC+CP G T
Sbjct: 1054 --GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT 1091
Score = 122 bits (295), Expect = 2e-27
Identities = 125/467 (26%), Positives = 179/467 (38%), Gaps = 56/467 (11%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCR-RGRCRNTAGSYTCL 64
C G CK+ F C+C+PGY G C +++EC P CR RG C++ +Y C
Sbjct: 575 CHYGSCKDGVATFTCLCRPGYT----GHHCETNINECSSQP--CRLRGTCQDPDNAYLCF 628
Query: 65 CEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G T C ++D+CA+ S C G C++ ++C CE GY + ++DE
Sbjct: 629 CLKG---TTGPNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGYTGSMCNS---NIDE 681
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C G C + F C C G+ T ++ C G AC
Sbjct: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHG----AC-RDSLNG 736
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDI 239
Y C G S N + NEC + P C +G +C+++ G C C G+ +I
Sbjct: 737 YKCDCDPGWSGTNCDINNNECESNP--CVNGGTCKDMTSGIVCTCREGF--SGPNCQTNI 792
Query: 240 DECDMHQSYCAGGQCRNTAG-SFTCVCP-EGTRHEPELQLCRDIDECEGETETHYIESDY 297
+EC + G + AG C+ P G E L C C E E DY
Sbjct: 793 NECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP-SPCRNGGECRQSE-DY 850
Query: 298 ERGD-IPPTFPTRTE---------LASPCDNGR-CINTHGGFECECELGYV---LDATAQ 343
E + PT + + + SPC +G C NTHG + C C+ GY +
Sbjct: 851 ESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDID 910
Query: 344 RCLDN---RRGSCWRRVVDGQCEA--AAPELLLRQEC--CCSVGLAWGSXXXXXXXXXXX 396
C N GSC + C+ ++ C S G+
Sbjct: 911 DCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTC 970
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
A G C + + GGTCV+ S+ C CPPG T
Sbjct: 971 TCP--AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT 1015
Score = 122 bits (294), Expect = 3e-27
Identities = 124/467 (26%), Positives = 185/467 (39%), Gaps = 62/467 (13%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C++ D + C C G+ G C ++D+C +P C G C + Y C CEPG
Sbjct: 616 GTCQDPDNAYLCFCL----KGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPG 669
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR-PTATRGACVDVDECEEQ 127
+ + +++DECA + GG C + F C C GY PT +V+EC
Sbjct: 670 YTGSMCN--SNIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLS----EVNECNSN 723
Query: 128 RVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
C +G C ++ ++C+C PG++ +N + V+ C S + C E
Sbjct: 724 P-CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCT-CRE 781
Query: 188 GPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQS 247
G S N +INEC + P G+C + GY+C C Y G ++ S
Sbjct: 782 GFSGPNCQTNINECASNP-CLNKGTCIDDVAGYKCNCLLPY----TGATCEVVLAPCAPS 836
Query: 248 YCA-GGQCRNTAG--SFTCVCPE-GTR--------HEPELQLCRDIDECEGETETH--YI 293
C GG+CR + SF+CVCP G + +E L CR C+ + +
Sbjct: 837 PCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHC 896
Query: 294 ESDYE----RGDIPPTFPTRTELASPCDNG------RCINTHGGFECECELGYVLD---- 339
++ Y DI P C +G C+ G CE ++
Sbjct: 897 QAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCR 956
Query: 340 --ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
A C+D+ +C CE P+ E C G G+
Sbjct: 957 NGANCTDCVDSYTCTCPAGFSGIHCENNTPDCT---ESSCFNG---GTCVDGINSFTCLC 1010
Query: 398 XKGFAKLDGATCRDV-DECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
GF G+ C+ V +EC S GGTC + G +RC CP G T
Sbjct: 1011 PPGFT---GSYCQHVVNECD-SRPCLLGGTCQDGRGLHRCTCPQGYT 1053
Score = 121 bits (292), Expect = 5e-27
Identities = 125/476 (26%), Positives = 185/476 (38%), Gaps = 61/476 (12%)
Query: 7 CTN-GICKNID----GGFECICKPGYESGSEGALC-RDVDE-CRDNPRVCRRGRCRN--T 57
C N G C +D + C C G+ G LC +D C NP CR G + T
Sbjct: 68 CKNAGTCHVVDRRGVADYACSCALGFS----GPLCLTPLDNACLTNP--CRNGGTCDLLT 121
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
Y C C PG++ + C D CA++ GG+C+ E S+ C C + R
Sbjct: 122 LTEYKCRCPPGWSGKS---CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCR-- 176
Query: 118 CVDVDEC-EEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPA 175
DV+EC ++ R+CR+ G CHN GS+RC C T N R + + C
Sbjct: 177 -QDVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRP 235
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPG-ACPH-GSCENLEPGYRCICDPGYHPDAD 233
G + C G + N +I++C PG C + G+C + Y C C P +
Sbjct: 236 TGDVTHECACLPGFTGQNCEENIDDC---PGNNCKNGGACVDGVNTYNCPCPPEW--TGQ 290
Query: 234 GLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEP--------ELQLCRDIDEC 284
D+DEC + + C GG C NT G + CVC G E C C
Sbjct: 291 YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATC 350
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT---HGGFECECELGYVLDAT 341
+ Y E + R + +++PC+ G +T +G C C GY A
Sbjct: 351 HDRVASFYCECPHGRTGLLCHLNDAC-ISNPCNEGSNCDTNPVNGKAICTCPSGYTGPAC 409
Query: 342 AQ---RCL-----DNRRGSCWRRVVDGQCEA----AAPELLLR-QECCCSVGLAWGSXXX 388
+Q C G C + +C+ P + EC + +
Sbjct: 410 SQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLD 469
Query: 389 XXXXXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ +G C + DECA S+ G C++ ++C+CP G T
Sbjct: 470 QIGEFQCMCMPGY---EGVHCEVNTDECA-SSPCLHNGRCLDKINEFQCECPTGFT 521
Score = 108 bits (259), Expect = 5e-23
Identities = 121/485 (24%), Positives = 187/485 (38%), Gaps = 75/485 (15%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCRDV-DECRDNPRVCRRG-RCRNTAG--SY 61
C N G C + G++C C Y GA C V C +P CR G CR + S+
Sbjct: 800 CLNKGTCIDDVAGYKCNCLLPYT----GATCEVVLAPCAPSP--CRNGGECRQSEDYESF 853
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
+C+C P D++EC G C N+ G ++C C+AGY + R D+
Sbjct: 854 SCVC-PTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGY---SGRNCETDI 909
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
D+C G C + + C+CLPGF D C G +C C
Sbjct: 910 DDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDC----V 965
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
+ Y CP G S + + +CT +C + G+C + + C+C PG+ C+
Sbjct: 966 DSYTCTCPAGFSGIHCENNTPDCT--ESSCFNGGTCVDGINSFTCLCPPGF---TGSYCQ 1020
Query: 238 D-IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR--------HEPELQLCRDIDECEGET 288
++ECD + GG C++ G C CP+G H + C++ +C +T
Sbjct: 1021 HVVNECD-SRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC-WQT 1078
Query: 289 ETHYIESDYERG------DIPPTF------PTRTELASPCDN-GRCINTHGGFECECELG 335
T Y + G D+P ++A C + G C++ C C+ G
Sbjct: 1079 HTQY-RCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAG 1137
Query: 336 YV---LDATAQRCLDN--RRGSCWRRVVDG-QCEAAAPELLLR-----QECCCSVGLAWG 384
Y + C + + G+ + G C+ A + EC G
Sbjct: 1138 YTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGG 1197
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCR-DVDEC-------ALSAELCAGGTCVNTDGSYRC 436
+ +G G C +VD+C + S + GTCV+ G Y C
Sbjct: 1198 TCLDLPNTYKCSCPRG---TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC 1254
Query: 437 DCPPG 441
CPPG
Sbjct: 1255 TCPPG 1259
Score = 101 bits (242), Expect = 5e-21
Identities = 126/479 (26%), Positives = 173/479 (36%), Gaps = 64/479 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N C +G C++ G++C C PG+ SG+ + + +EC NP V G C++
Sbjct: 721 NSNPCVHGACRDSLNGYKCDCDPGW-SGTNCDI--NNNECESNPCV-NGGTCKDMTSGIV 776
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF + +++ECA++ G C++ ++C C Y T C V
Sbjct: 777 CTCREGF--SGPNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPY----TGATCEVVL 830
Query: 123 ECEEQRVCRN-GRCHNTPG--SFRCEC----LPGFTLSNDGRTCLGLKLGWGVSCQACPA 175
CRN G C + SF C C G T D C+ G SCQ
Sbjct: 831 APCAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQ--NT 888
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADG 234
G Y C G S N DI++C P C + GSC + C C PG+
Sbjct: 889 HGX--YRCHCQAGYSGRNCETDIDDCR--PNPCHNGGSCTDGINTAFCDCLPGFR---GT 941
Query: 235 LC-RDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETET 290
C DI+EC G C + S+TC CP G E C + G T
Sbjct: 942 FCEEDINEC-ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCV 1000
Query: 291 HYIESDYERGDIPPTFPTR--TELASPCDN------GRCINTHGGFECECELGYV---LD 339
I S PP F + + CD+ G C + G C C GY
Sbjct: 1001 DGINS--FTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQ 1058
Query: 340 ATAQRCLDN---RRGSCWRRVVDGQCEAAA---------PEL---LLRQECCCSVGLAWG 384
C + G CW+ +CE + P + + Q V
Sbjct: 1059 NLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQ 1118
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCRD-VDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
+ A G+ C D VDEC+ S C G TC + G Y C C G
Sbjct: 1119 HGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAG 1175
Score = 89.4 bits (212), Expect = 2e-17
Identities = 94/367 (25%), Positives = 146/367 (39%), Gaps = 53/367 (14%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSY 61
NGG C +GI F C+C PG+ G+ C+ V+EC P + G C++ G +
Sbjct: 995 NGGTCVDGI-----NSFTCLCPPGF----TGSYCQHVVNECDSRPCLL-GGTCQDGRGLH 1044
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYR------PTAT 114
C C G+ C ++ S CK GG+C + ++C C +G+ P+ +
Sbjct: 1045 RCTCPQGY---TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVS 1101
Query: 115 RGACVDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQA 172
+ R+C++ G C + + C C G+T G C L S CQ
Sbjct: 1102 CEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQN 1157
Query: 173 CPAQGSEL--YAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCIC---DP 226
L Y+ C G N +I+EC + P C + G+C +L Y+C C
Sbjct: 1158 GATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQ 1215
Query: 227 GYHPD--ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDI 281
G H + D +D G C + G ++C CP G R E ++ C
Sbjct: 1216 GVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLS- 1274
Query: 282 DECEGETETHYIE--SDYERGDIPPTFPTRTE------LASPCDN-GRCI---NTHGGFE 329
+ C+ + ++ +D+ R E PC N G C NT GF
Sbjct: 1275 NPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFI 1334
Query: 330 CECELGY 336
C+C G+
Sbjct: 1335 CKCPAGF 1341
Score = 81.8 bits (193), Expect = 5e-15
Identities = 80/286 (27%), Positives = 116/286 (40%), Gaps = 43/286 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRD-------NPRVCRRGRCRNT 57
C NG C ++ ++C C G++G C +VD+C +P+ G C +
Sbjct: 1193 CQNGGTCLDLPNTYKCSCP----RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQ 1248
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGG--RCVNSEGSFQCVCEAGYRPTATR 115
G Y+C C PGF DV+EC ++ G CV F C C AG+ T R
Sbjct: 1249 VGGYSCTCPPGFVGERCE--GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH--TGRR 1304
Query: 116 GACVDVDECEEQRVCRNGRC---HNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVS 169
V ++ C+ + G C NT F C+C GF T ND RTC L+ G +
Sbjct: 1305 CESV-INGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGT 1363
Query: 170 CQACPAQGSELYAVLCP-EGPSKDNGGADINECTAVPGACPHGSCE--NLEPGYRCICDP 226
C + P S L P GP + + C G+CE + P YRC+C
Sbjct: 1364 CISGPR--SPTCLCLGPFTGPECQFPAS--SPCLGGNPCYNQGTCEPTSESPFYRCLCPA 1419
Query: 227 GY---------HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
+ + G RDI + + C +C+ AG+ C
Sbjct: 1420 KFNGLLCHILDYSFGGGAGRDIPP-PLIEEACELPECQEDAGNKVC 1464
Score = 65.7 bits (153), Expect = 3e-10
Identities = 55/191 (28%), Positives = 73/191 (38%), Gaps = 24/191 (12%)
Query: 86 DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN-GRCH----NTPG 140
++ GG+C + G+ CVC + C D + C C+N G CH
Sbjct: 29 ETCLNGGKCEAANGTEACVCGGAF----VGPRCQDPNPC-LSTPCKNAGTCHVVDRRGVA 83
Query: 141 SFRCECLPGFT----LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA 196
+ C C GF+ L+ CL G +C Y CP G S
Sbjct: 84 DYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTE---YKCRCPPGWS-GKSCQ 139
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCA-GGQC 254
+ C + P A G C E Y C C P +H CR D++EC C GG C
Sbjct: 140 QADPCASNPCA-NGGQCLPFEASYICHCPPSFHGPT---CRQDVNECGQKPRLCRHGGTC 195
Query: 255 RNTAGSFTCVC 265
N GS+ CVC
Sbjct: 196 HNEVGSYRCVC 206
>AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens
cDNA FLJ14438 fis, clone HEMBB1000317, weakly similar to
FIBULIN-1, ISOFORM D PRECURSOR. ).
Length = 741
Score = 176 bits (428), Expect = 2e-43
Identities = 106/276 (38%), Positives = 137/276 (49%), Gaps = 22/276 (7%)
Query: 23 CKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADV 80
C G+ S G C D DEC NP C C N G+Y C C G A G C D+
Sbjct: 315 CPSGFTLDSVGPFCADEDECAAGNP--CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 371
Query: 81 DECAADS-MCKGGR-CVNSEGSFQCV--CEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
DECA C G+ C N+ GS++CV C +G+R T+ +C D++EC+E C RC
Sbjct: 372 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCF 430
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---QACP-AQGSELYAVLCPEGPSKD 192
N GSF C C PG+ L GR C+ + C Q C +G LCP G +K
Sbjct: 431 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 488
Query: 193 NGGA--DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSY 248
G DI+EC C + CEN YRC+C GY G C DIDEC+ +
Sbjct: 489 ENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECE-NTDA 547
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C +C+NT GS+ C+CP G + + C+DIDEC
Sbjct: 548 CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 582
Score = 167 bits (406), Expect = 7e-41
Identities = 109/296 (36%), Positives = 147/296 (49%), Gaps = 31/296 (10%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G C++ C N G + C C G ++G C+D+DEC C G+ C NT GSY
Sbjct: 337 GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYR 395
Query: 63 CL--CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C+ C GF T+ G C D++EC S C RC N+ GSF C CE GY+ + C+
Sbjct: 396 CVVRCGSGFRRTSDGLSCQDINECQESSPCH-QRCFNAIGSFHCGCEPGYQLKGRK--CM 452
Query: 120 DVDECEEQRVCR-NGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGV-SC---Q 171
DV+EC Q VCR + C NT G ++C C G T + +G TC+ + + G C Q
Sbjct: 453 DVNEC-RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQ 510
Query: 172 ACP-AQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPG 227
C +GS Y +CP G G DI+EC AC H C+N Y+CIC PG
Sbjct: 511 ICENTRGS--YRCVCPRGYRSQGVGRPCMDIDECENT-DACQH-ECKNTFGSYQCICPPG 566
Query: 228 YHPDADG-LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV---CPEGTRHEPELQLC 278
Y +G C+DIDEC +C + C N GS+ C+ CP + +P C
Sbjct: 567 YQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 622
Score = 138 bits (333), Expect = 5e-32
Identities = 88/232 (37%), Positives = 109/232 (46%), Gaps = 14/232 (6%)
Query: 65 CEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF + G +CAD DECAA + C C N+ G++ C C G A C D+DE
Sbjct: 315 CPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDE 373
Query: 124 CEEQR-VCRNGR-CHNTPGSFRC--ECLPGFTLSNDGRTCLGLKLGWGVS-C-QACPAQG 177
C R C G+ C NT GS+RC C GF ++DG +C + S C Q C
Sbjct: 374 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAI 433
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCI--CDPGYHPDADG 234
+ P K D+NEC C P C+N GY+CI C G +G
Sbjct: 434 GSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 491
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C DIDEC C Q C NT GS+ CVCP G R + + C DIDECE
Sbjct: 492 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECE 543
Score = 119 bits (287), Expect = 2e-26
Identities = 63/158 (39%), Positives = 80/158 (50%), Gaps = 11/158 (6%)
Query: 12 CKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
CKN GG++CI C G G C D+DEC+D CR + C NT GSY C+C G
Sbjct: 468 CKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRG 526
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+ G C D+DEC C+ C N+ GS+QC+C GY+ T C D+DEC EQ
Sbjct: 527 YRSQGVGRPCMDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQ 585
Query: 128 RV-C-RNGRCHNTPGSFRC---ECLPGFTLSNDGRTCL 160
V C N C N GS++C C P + CL
Sbjct: 586 NVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCL 623
Score = 110 bits (264), Expect = 1e-23
Identities = 105/365 (28%), Positives = 139/365 (38%), Gaps = 71/365 (19%)
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S+G C +G+ + C D DEC C + CHN G++ C C G T++ DG
Sbjct: 307 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADG 365
Query: 157 RTCLGL-KLGWGV-SCQA---CPAQ-GSELYAVLCPEGPSKDNGGA---DINECTAVPGA 207
RTC + + G +C A C GS V C G + + G DINEC
Sbjct: 366 RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSP 424
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV-- 264
C H C N + C C+PGY C D++EC Q+ C Q C+NT G + C+
Sbjct: 425 C-HQRCFNAIGSFHCGCEPGYQLKGRK-CMDVNEC--RQNVCRPDQHCKNTRGGYKCIDL 480
Query: 265 CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT 324
CP G + E C DIDEC+ T + Y N C NT
Sbjct: 481 CPNGMT-KAENGTCIDIDECKDGTH----QCRY--------------------NQICENT 515
Query: 325 HGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG 384
G + C C GY + C+D C C+ +C C G
Sbjct: 516 RGSYRCVCPRGYRSQGVGRPCMD--IDECEN---TDACQHECKNTFGSYQCICPPGYQ-- 568
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCPP 440
+G TC+D+DEC C C N GSY+C CPP
Sbjct: 569 -----------------LTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPP 611
Query: 441 GLTLD 445
D
Sbjct: 612 NYQRD 616
Score = 97.1 bits (231), Expect = 1e-19
Identities = 47/117 (40%), Positives = 63/117 (53%), Gaps = 8/117 (6%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
N IC+N G + C+C GY S G C D+DEC +N C+ C+NT GSY C+C PG
Sbjct: 509 NQICENTRGSYRCVCPRGYRSQGVGRPCMDIDEC-ENTDACQH-ECKNTFGSYQCICPPG 566
Query: 69 FAPTAAG-YCADVDECAADSM-CKGGR-CVNSEGSFQCV---CEAGYRPTATRGACV 119
+ T G C D+DEC ++ C R C N GS+QC+ C Y+ G C+
Sbjct: 567 YQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCL 623
Score = 49.6 bits (113), Expect = 2e-05
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 405 DGATCRDVDECALSAELC-AGGTCVNTDGSYRC--DCPPGLTLDSTG 448
DG TC+D+DECAL C AG C NT GSYRC C G S G
Sbjct: 364 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDG 410
Score = 46.4 bits (105), Expect = 2e-04
Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDSTG 448
G K + TC D+DEC C C NT GSYRC CP G G
Sbjct: 484 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG 533
Score = 44.0 bits (99), Expect = 0.001
Identities = 20/43 (46%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D+DEC + + C C NT GSY+C CPPG L G
Sbjct: 533 GRPCMDIDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNG 573
Score = 40.3 bits (90), Expect = 0.014
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D DECA + C+ +C N G+Y C CP GLT+ + G
Sbjct: 325 GPFCADEDECA-AGNPCSH-SCHNAMGTYYCSCPKGLTIAADG 365
Score = 36.3 bits (80), Expect = 0.22
Identities = 53/198 (26%), Positives = 76/198 (38%), Gaps = 33/198 (16%)
Query: 265 CPEGTRHEPELQLCRDIDECE-GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
CP G + C D DEC G +H + G + P +A+ + I+
Sbjct: 315 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHN--AMGTYYCSCPKGLTIAADGRTCQDID 372
Query: 324 THGGFECECELGYVLDAT--AQRCLDNRRGSCWRRVVDG-------QCEAAAPELLLRQE 374
C G D T + RC+ R GS +RR DG +C+ ++P Q
Sbjct: 373 ECALGRHTCHAGQDCDNTIGSYRCVV-RCGSGFRRTSDGLSCQDINECQESSP---CHQR 428
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGS 433
C ++G G+ +L G C DV+EC +C C NT G
Sbjct: 429 CFNAIG-----------SFHCGCEPGY-QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGG 474
Query: 434 YRCD--CPPGLTLDSTGT 449
Y+C CP G+T GT
Sbjct: 475 YKCIDLCPNGMTKAENGT 492
>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
Length = 2556
Score = 176 bits (428), Expect = 2e-43
Identities = 141/468 (30%), Positives = 197/468 (42%), Gaps = 62/468 (13%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N C + G F+C+C PGYE G C + DEC +P + GRC + + C
Sbjct: 461 CQNDATCLDQIGEFQCMCMPGYE----GVHCEVNTDECASSPCL-HNGRCLDKINEFQCE 515
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C GF Y DVDECA+ G +C++ ++ CVC GY T VD+DEC
Sbjct: 516 CPTGFTGHLCQY--DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE---VDIDEC 570
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-----E 179
+ C G C + +F C C PG+T G C + S Q C +G+
Sbjct: 571 DPD-PCHYGSCKDGVATFTCLCRPGYT----GHHC-ETNIN-ECSSQPCRLRGTCQDPDN 623
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCR-D 238
Y C +G + N ++++C + P C G+C + GY C C+PGY +C +
Sbjct: 624 AYLCFCLKGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGY---TGSMCNSN 678
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
IDEC + + GG C + FTC CPEG H+P +++EC H D
Sbjct: 679 IDECAGNPCH-NGGTCEDGINGFTCRCPEG-YHDP--TCLSEVNECNSNPCVHGACRDSL 734
Query: 299 RG---DIPPTFP-TRTEL------ASPCDN-GRCINTHGGFECECELGYV---LDATAQR 344
G D P + T ++ ++PC N G C + G C C G+
Sbjct: 735 NGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINE 794
Query: 345 CLDN---RRGSCWRRVVDGQCEAAAP------ELLLRQECCCSVGLAWGSXXXXXXXXXX 395
C N +G+C V +C P E++L C S G
Sbjct: 795 CASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVL-APCAPSPCRNGGECRQSEDYESF 853
Query: 396 XXXKGFAKLDGATCR-DVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
A G TC D++EC LS C G +C NT G YRC C G
Sbjct: 854 SCVCPTAGAKGQTCEVDINECVLSP--CRHGASCQNTHGXYRCHCQAG 899
Score = 128 bits (310), Expect = 3e-29
Identities = 127/467 (27%), Positives = 187/467 (40%), Gaps = 56/467 (11%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA---GSYT 62
C +G C + F C C G G LC D C NP C G +T G
Sbjct: 344 CFHGATCHDRVASFYCECP----HGRTGLLCHLNDACISNP--CNEGSNCDTNPVNGKAI 397
Query: 63 CLCEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCVCEAGYRPTATRGAC-V 119
C C G+ A DVDEC+ + C+ G+C+N+ GSF+C C GY T C +
Sbjct: 398 CTCPSGYTGPACSQ--DVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEI 451
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
DV+EC + C + G F+C C+PG+ + + C + +E
Sbjct: 452 DVNECVSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECASSPCLHNGRCLDKINE 511
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
+ CP G + D++EC + P C +G+ C + Y C+C GY C
Sbjct: 512 -FQCECPTGFTGHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGY---TGTHCEV 565
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQL-------CRDIDECEGETE 289
DIDECD C G C++ +FTC+C G T H E + CR C+ + +
Sbjct: 566 DIDECDPDP--CHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRLRGTCQ-DPD 622
Query: 290 THYIESDYERGDIPPTFPTRTE--LASPCDNGRCINTHGGFECECELGY---VLDATAQR 344
Y+ +G P + +SPCD+G C++ G+EC CE GY + ++
Sbjct: 623 NAYL-CFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNSNIDE 681
Query: 345 CLDN---RRGSCWRRVVDGQCEAAA----PELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
C N G+C + C P L C S G+
Sbjct: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDC 741
Query: 398 XKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLT 443
G++ G C D++ + C GGTC + C C G +
Sbjct: 742 DPGWS---GTNC-DINNNECESNPCVNGGTCKDMTSGIVCTCREGFS 784
Score = 126 bits (304), Expect = 2e-28
Identities = 127/461 (27%), Positives = 181/461 (39%), Gaps = 69/461 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + + C C G+ G C + +C ++ G C + S+TCL
Sbjct: 955 CRNGANCTDCVDSYTCTCPAGFS----GIHCENNTPDCTESS-CFNGGTCVDGINSFTCL 1009
Query: 65 CEPGFAPTAAGYCADV-DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PGF YC V +EC + GG C + G +C C GY T C ++
Sbjct: 1010 CPPGFT---GSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGY----TGPNCQNLVH 1062
Query: 124 CEEQRVCRNG-RCHNTPGSFRCECLPGFT-LSND--GRTCLGLKLGWGVS----CQ---A 172
+ C+NG +C T +RCEC G+T L D +C GV CQ
Sbjct: 1063 WCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGL 1122
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPD 231
C G+ + C G + ++EC+ P C +G+ C + GY C C GYH
Sbjct: 1123 CVDAGNTHHC-RCQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSCKCVAGYH-- 1177
Query: 232 ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
+IDEC H GG C + ++ C CP GT+ + ++D+C
Sbjct: 1178 GVNCSEEIDECLSHPCQ-NGGTCLDLPNTYKCSCPRGTQG---VHCEINVDDCN------ 1227
Query: 292 YIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECECELGYV---LDATAQRCLD 347
PP P + C +NG C++ GG+ C C G+V + CL
Sbjct: 1228 -----------PPVDPVSR--SPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLS 1274
Query: 348 N---RRG--SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF- 401
N RG +C +RV D CE A R E + +GF
Sbjct: 1275 NPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFI 1334
Query: 402 ----AKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A +GATC + S GGTC++ S C C
Sbjct: 1335 CKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLC 1375
Score = 125 bits (302), Expect = 3e-28
Identities = 124/460 (26%), Positives = 183/460 (39%), Gaps = 76/460 (16%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C +GI GF C C GY + +V+EC NP C G CR++ Y
Sbjct: 689 NGGTCEDGI-----NGFTCRCPEGYH---DPTCLSEVNECNSNP--CVHGACRDSLNGYK 738
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C+PG++ T + +EC ++ GG C + C C G+ + +++
Sbjct: 739 CDCDPGWSGTNCDI--NNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQ---TNIN 793
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQ---AC-PAQG 177
EC G C + ++C CL +T G TC + S C+ C ++
Sbjct: 794 ECASNPCLNKGTCIDDVAGYKCNCLLPYT----GATCEVVLAPCAPSPCRNGGECRQSED 849
Query: 178 SELYAVLCPEGPSKDNG-GADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGL 235
E ++ +CP +K DINEC P C HG SC+N YRC C GY
Sbjct: 850 YESFSCVCPTAGAKGQTCEVDINECVLSP--CRHGASCQNTHGXYRCHCQAGY--SGRNC 905
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH---EPELQLCRDIDECE-GETETH 291
DID+C + + GG C + + C C G R E ++ C D C G T
Sbjct: 906 ETDIDDCRPNPCH-NGGSCTDGINTAFCDCLPGFRGTFCEEDINECAS-DPCRNGANCTD 963
Query: 292 YIES-------DYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLDATAQ 343
++S + P TE S C NG C++ F C C G+
Sbjct: 964 CVDSYTCTCPAGFSGIHCENNTPDCTE--SSCFNGGTCVDGINSFTCLCPPGFT------ 1015
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
GS + VV+ +C++ C +G G+ +G+
Sbjct: 1016 -------GSYCQHVVN-ECDSRP----------CLLG---GTCQDGRGLHRCTCPQGYT- 1053
Query: 404 LDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G C+++ S+ GG C T YRC+CP G T
Sbjct: 1054 --GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT 1091
Score = 122 bits (295), Expect = 2e-27
Identities = 125/467 (26%), Positives = 179/467 (38%), Gaps = 56/467 (11%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCR-RGRCRNTAGSYTCL 64
C G CK+ F C+C+PGY G C +++EC P CR RG C++ +Y C
Sbjct: 575 CHYGSCKDGVATFTCLCRPGYT----GHHCETNINECSSQP--CRLRGTCQDPDNAYLCF 628
Query: 65 CEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G T C ++D+CA+ S C G C++ ++C CE GY + ++DE
Sbjct: 629 CLKG---TTGPNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGYTGSMCNS---NIDE 681
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C G C + F C C G+ T ++ C G AC
Sbjct: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHG----AC-RDSLNG 736
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDI 239
Y C G S N + NEC + P C +G +C+++ G C C G+ +I
Sbjct: 737 YKCDCDPGWSGTNCDINNNECESNP--CVNGGTCKDMTSGIVCTCREGF--SGPNCQTNI 792
Query: 240 DECDMHQSYCAGGQCRNTAG-SFTCVCP-EGTRHEPELQLCRDIDECEGETETHYIESDY 297
+EC + G + AG C+ P G E L C C E E DY
Sbjct: 793 NECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP-SPCRNGGECRQSE-DY 850
Query: 298 ERGD-IPPTFPTRTE---------LASPCDNGR-CINTHGGFECECELGYV---LDATAQ 343
E + PT + + + SPC +G C NTHG + C C+ GY +
Sbjct: 851 ESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDID 910
Query: 344 RCLDN---RRGSCWRRVVDGQCEA--AAPELLLRQEC--CCSVGLAWGSXXXXXXXXXXX 396
C N GSC + C+ ++ C S G+
Sbjct: 911 DCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTC 970
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
A G C + + GGTCV+ S+ C CPPG T
Sbjct: 971 TCP--AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT 1015
Score = 122 bits (294), Expect = 3e-27
Identities = 124/467 (26%), Positives = 185/467 (39%), Gaps = 62/467 (13%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C++ D + C C G+ G C ++D+C +P C G C + Y C CEPG
Sbjct: 616 GTCQDPDNAYLCFCL----KGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPG 669
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR-PTATRGACVDVDECEEQ 127
+ + +++DECA + GG C + F C C GY PT +V+EC
Sbjct: 670 YTGSMCN--SNIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLS----EVNECNSN 723
Query: 128 RVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
C +G C ++ ++C+C PG++ +N + V+ C S + C E
Sbjct: 724 P-CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCT-CRE 781
Query: 188 GPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQS 247
G S N +INEC + P G+C + GY+C C Y G ++ S
Sbjct: 782 GFSGPNCQTNINECASNP-CLNKGTCIDDVAGYKCNCLLPY----TGATCEVVLAPCAPS 836
Query: 248 YCA-GGQCRNTAG--SFTCVCPE-GTR--------HEPELQLCRDIDECEGETETH--YI 293
C GG+CR + SF+CVCP G + +E L CR C+ + +
Sbjct: 837 PCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHC 896
Query: 294 ESDYE----RGDIPPTFPTRTELASPCDNG------RCINTHGGFECECELGYVLD---- 339
++ Y DI P C +G C+ G CE ++
Sbjct: 897 QAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCR 956
Query: 340 --ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
A C+D+ +C CE P+ E C G G+
Sbjct: 957 NGANCTDCVDSYTCTCPAGFSGIHCENNTPDCT---ESSCFNG---GTCVDGINSFTCLC 1010
Query: 398 XKGFAKLDGATCRDV-DECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
GF G+ C+ V +EC S GGTC + G +RC CP G T
Sbjct: 1011 PPGFT---GSYCQHVVNECD-SRPCLLGGTCQDGRGLHRCTCPQGYT 1053
Score = 121 bits (292), Expect = 5e-27
Identities = 125/476 (26%), Positives = 185/476 (38%), Gaps = 61/476 (12%)
Query: 7 CTN-GICKNID----GGFECICKPGYESGSEGALC-RDVDE-CRDNPRVCRRGRCRN--T 57
C N G C +D + C C G+ G LC +D C NP CR G + T
Sbjct: 68 CKNAGTCHVVDRRGVADYACSCALGFS----GPLCLTPLDNACLTNP--CRNGGTCDLLT 121
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
Y C C PG++ + C D CA++ GG+C+ E S+ C C + R
Sbjct: 122 LTEYKCRCPPGWSGKS---CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCR-- 176
Query: 118 CVDVDEC-EEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPA 175
DV+EC ++ R+CR+ G CHN GS+RC C T N R + + C
Sbjct: 177 -QDVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRP 235
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPG-ACPH-GSCENLEPGYRCICDPGYHPDAD 233
G + C G + N +I++C PG C + G+C + Y C C P +
Sbjct: 236 TGDVTHECACLPGFTGQNCEENIDDC---PGNNCKNGGACVDGVNTYNCPCPPEW--TGQ 290
Query: 234 GLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEP--------ELQLCRDIDEC 284
D+DEC + + C GG C NT G + CVC G E C C
Sbjct: 291 YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATC 350
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT---HGGFECECELGYVLDAT 341
+ Y E + R + +++PC+ G +T +G C C GY A
Sbjct: 351 HDRVASFYCECPHGRTGLLCHLNDAC-ISNPCNEGSNCDTNPVNGKAICTCPSGYTGPAC 409
Query: 342 AQ---RCL-----DNRRGSCWRRVVDGQCEA----AAPELLLR-QECCCSVGLAWGSXXX 388
+Q C G C + +C+ P + EC + +
Sbjct: 410 SQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLD 469
Query: 389 XXXXXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ +G C + DECA S+ G C++ ++C+CP G T
Sbjct: 470 QIGEFQCMCMPGY---EGVHCEVNTDECA-SSPCLHNGRCLDKINEFQCECPTGFT 521
Score = 108 bits (259), Expect = 5e-23
Identities = 121/485 (24%), Positives = 187/485 (38%), Gaps = 75/485 (15%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCRDV-DECRDNPRVCRRG-RCRNTAG--SY 61
C N G C + G++C C Y GA C V C +P CR G CR + S+
Sbjct: 800 CLNKGTCIDDVAGYKCNCLLPYT----GATCEVVLAPCAPSP--CRNGGECRQSEDYESF 853
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
+C+C P D++EC G C N+ G ++C C+AGY + R D+
Sbjct: 854 SCVC-PTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGY---SGRNCETDI 909
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
D+C G C + + C+CLPGF D C G +C C
Sbjct: 910 DDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDC----V 965
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
+ Y CP G S + + +CT +C + G+C + + C+C PG+ C+
Sbjct: 966 DSYTCTCPAGFSGIHCENNTPDCT--ESSCFNGGTCVDGINSFTCLCPPGF---TGSYCQ 1020
Query: 238 D-IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR--------HEPELQLCRDIDECEGET 288
++ECD + GG C++ G C CP+G H + C++ +C +T
Sbjct: 1021 HVVNECD-SRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC-WQT 1078
Query: 289 ETHYIESDYERG------DIPPTF------PTRTELASPCDN-GRCINTHGGFECECELG 335
T Y + G D+P ++A C + G C++ C C+ G
Sbjct: 1079 HTQY-RCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAG 1137
Query: 336 YV---LDATAQRCLDN--RRGSCWRRVVDG-QCEAAAPELLLR-----QECCCSVGLAWG 384
Y + C + + G+ + G C+ A + EC G
Sbjct: 1138 YTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGG 1197
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCR-DVDEC-------ALSAELCAGGTCVNTDGSYRC 436
+ +G G C +VD+C + S + GTCV+ G Y C
Sbjct: 1198 TCLDLPNTYKCSCPRG---TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC 1254
Query: 437 DCPPG 441
CPPG
Sbjct: 1255 TCPPG 1259
Score = 101 bits (242), Expect = 5e-21
Identities = 126/479 (26%), Positives = 173/479 (36%), Gaps = 64/479 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N C +G C++ G++C C PG+ SG+ + + +EC NP V G C++
Sbjct: 721 NSNPCVHGACRDSLNGYKCDCDPGW-SGTNCDI--NNNECESNPCV-NGGTCKDMTSGIV 776
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF + +++ECA++ G C++ ++C C Y T C V
Sbjct: 777 CTCREGF--SGPNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPY----TGATCEVVL 830
Query: 123 ECEEQRVCRN-GRCHNTPG--SFRCEC----LPGFTLSNDGRTCLGLKLGWGVSCQACPA 175
CRN G C + SF C C G T D C+ G SCQ
Sbjct: 831 APCAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQ--NT 888
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADG 234
G Y C G S N DI++C P C + GSC + C C PG+
Sbjct: 889 HGX--YRCHCQAGYSGRNCETDIDDCR--PNPCHNGGSCTDGINTAFCDCLPGFR---GT 941
Query: 235 LC-RDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETET 290
C DI+EC G C + S+TC CP G E C + G T
Sbjct: 942 FCEEDINEC-ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCV 1000
Query: 291 HYIESDYERGDIPPTFPTR--TELASPCDN------GRCINTHGGFECECELGYV---LD 339
I S PP F + + CD+ G C + G C C GY
Sbjct: 1001 DGINS--FTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQ 1058
Query: 340 ATAQRCLDN---RRGSCWRRVVDGQCEAAA---------PEL---LLRQECCCSVGLAWG 384
C + G CW+ +CE + P + + Q V
Sbjct: 1059 NLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQ 1118
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCRD-VDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
+ A G+ C D VDEC+ S C G TC + G Y C C G
Sbjct: 1119 HGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAG 1175
Score = 89.4 bits (212), Expect = 2e-17
Identities = 94/367 (25%), Positives = 146/367 (39%), Gaps = 53/367 (14%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSY 61
NGG C +GI F C+C PG+ G+ C+ V+EC P + G C++ G +
Sbjct: 995 NGGTCVDGI-----NSFTCLCPPGF----TGSYCQHVVNECDSRPCLL-GGTCQDGRGLH 1044
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYR------PTAT 114
C C G+ C ++ S CK GG+C + ++C C +G+ P+ +
Sbjct: 1045 RCTCPQGY---TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVS 1101
Query: 115 RGACVDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQA 172
+ R+C++ G C + + C C G+T G C L S CQ
Sbjct: 1102 CEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQN 1157
Query: 173 CPAQGSEL--YAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCIC---DP 226
L Y+ C G N +I+EC + P C + G+C +L Y+C C
Sbjct: 1158 GATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQ 1215
Query: 227 GYHPD--ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDI 281
G H + D +D G C + G ++C CP G R E ++ C
Sbjct: 1216 GVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLS- 1274
Query: 282 DECEGETETHYIE--SDYERGDIPPTFPTRTE------LASPCDN-GRCI---NTHGGFE 329
+ C+ + ++ +D+ R E PC N G C NT GF
Sbjct: 1275 NPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFI 1334
Query: 330 CECELGY 336
C+C G+
Sbjct: 1335 CKCPAGF 1341
Score = 81.8 bits (193), Expect = 5e-15
Identities = 80/286 (27%), Positives = 116/286 (40%), Gaps = 43/286 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRD-------NPRVCRRGRCRNT 57
C NG C ++ ++C C G++G C +VD+C +P+ G C +
Sbjct: 1193 CQNGGTCLDLPNTYKCSCP----RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQ 1248
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGG--RCVNSEGSFQCVCEAGYRPTATR 115
G Y+C C PGF DV+EC ++ G CV F C C AG+ T R
Sbjct: 1249 VGGYSCTCPPGFVGERCE--GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH--TGRR 1304
Query: 116 GACVDVDECEEQRVCRNGRC---HNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVS 169
V ++ C+ + G C NT F C+C GF T ND RTC L+ G +
Sbjct: 1305 CESV-INGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGT 1363
Query: 170 CQACPAQGSELYAVLCP-EGPSKDNGGADINECTAVPGACPHGSCE--NLEPGYRCICDP 226
C + P S L P GP + + C G+CE + P YRC+C
Sbjct: 1364 CISGPR--SPTCLCLGPFTGPECQFPAS--SPCLGGNPCYNQGTCEPTSESPFYRCLCPA 1419
Query: 227 GY---------HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
+ + G RDI + + C +C+ AG+ C
Sbjct: 1420 KFNGLLCHILDYSFGGGAGRDIPP-PLIEEACELPECQEDAGNKVC 1464
Score = 65.7 bits (153), Expect = 3e-10
Identities = 55/191 (28%), Positives = 73/191 (38%), Gaps = 24/191 (12%)
Query: 86 DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN-GRCH----NTPG 140
++ GG+C + G+ CVC + C D + C C+N G CH
Sbjct: 29 ETCLNGGKCEAANGTEACVCGGAF----VGPRCQDPNPC-LSTPCKNAGTCHVVDRRGVA 83
Query: 141 SFRCECLPGFT----LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA 196
+ C C GF+ L+ CL G +C Y CP G S
Sbjct: 84 DYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTE---YKCRCPPGWS-GKSCQ 139
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCA-GGQC 254
+ C + P A G C E Y C C P +H CR D++EC C GG C
Sbjct: 140 QADPCASNPCA-NGGQCLPFEASYICHCPPSFHGPT---CRQDVNECGQKPRLCRHGGTC 195
Query: 255 RNTAGSFTCVC 265
N GS+ CVC
Sbjct: 196 HNEVGSYRCVC 206
>AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 175 bits (426), Expect = 3e-43
Identities = 123/361 (34%), Positives = 162/361 (44%), Gaps = 46/361 (12%)
Query: 7 CTNGI-CKNIDGGFECI----CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGS 60
C+ G C N G F C C+PGY +G C DVDEC C+ G C+NT GS
Sbjct: 777 CSRGEHCVNTLGSFHCYKALTCEPGYAL-KDGE-CEDVDECAMGTHTCQPGFLCQNTKGS 834
Query: 61 YTCL----CEPGFAPTAAGYCADVDECAADSM-CKGG-RCVNSEGSFQC-----VCEAGY 109
+ C C GF G C D++EC + S C+ G C+N+ GS+ C +C GY
Sbjct: 835 FYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGY 894
Query: 110 RPTATRGACVDVDECEEQ-RVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW- 166
+ CVDV+ECE C G+ CHN PGS+RC+C GF GR C+ + W
Sbjct: 895 HASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWA 954
Query: 167 --GVSCQACPAQGSELYAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYR 221
G CQ Y C G + D+NEC A C C N+ Y+
Sbjct: 955 SPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA--QRCSQ-ECANIYGSYQ 1011
Query: 222 CICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE-GTRHEPELQLCR 279
C C GY DG C DIDEC +C N GS+ C CPE G + C+
Sbjct: 1012 CYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCK 1071
Query: 280 DIDECE------GETET-HYIESDYE--RGDIPPTFPTRTELASPCDNGRCINTHGGFEC 330
D+DEC E ET H I+ + R + PP + ++ + C+ C H EC
Sbjct: 1072 DVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK--TKCERTTC---HDFLEC 1126
Query: 331 E 331
+
Sbjct: 1127 Q 1127
Score = 170 bits (414), Expect = 8e-42
Identities = 127/392 (32%), Positives = 167/392 (42%), Gaps = 51/392 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCRNTAGSY 61
+ G C +C + G C C PGY ++G C D DEC C RR C NT GS+
Sbjct: 685 DNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSF 743
Query: 62 TC-----LCEPGFAPTAAGYCADVDECAAD--SMCKGGRCVNSEGSFQC----VCEAGYR 110
C LC G+ A C +EC D + +G CVN+ GSF C CE GY
Sbjct: 744 YCVNHTVLCADGYILNAHRKCVGKNECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY- 802
Query: 111 PTATRGACVDVDECE-EQRVCRNG-RCHNTPGSFRCE----CLPGFTLSNDGR------- 157
G C DVDEC C+ G C NT GSF C+ C+ GF +G
Sbjct: 803 -ALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINEC 861
Query: 158 TCLGLKLGWGVSC-QACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHGS- 212
T L G SC + + ++C G + GA D+NEC C G
Sbjct: 862 TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQV 921
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
C NL YRC C G+ DA G C D++EC C NT GS+ C C G
Sbjct: 922 CHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL 981
Query: 272 EPELQLCRDIDECEGE---TETHYIESDYE----RG-DIPPTFPTRTELASPCDNG---- 319
+ + C D++ECE + E I Y+ +G + T T++ C G
Sbjct: 982 AADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDI-DECAQGAGIL 1040
Query: 320 ---RCINTHGGFECEC-ELGYVLDATAQRCLD 347
RC+N G ++C C E GY + A + C D
Sbjct: 1041 CTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1072
Score = 141 bits (342), Expect = 4e-33
Identities = 143/452 (31%), Positives = 184/452 (40%), Gaps = 82/452 (18%)
Query: 42 CRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDEC--AADSMCKGGRCVNSE 98
C+DN C++ C GS C C PG+A A G C D DEC A + CVN+
Sbjct: 683 CKDNGP-CKQV-CSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTL 740
Query: 99 GSFQCV-----CEAGYRPTATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRC----ECL 147
GSF CV C GY A R CV +EC + C G C NT GSF C C
Sbjct: 741 GSFYCVNHTVLCADGYILNAHR-KCVGKNECVTDLHTCSRGEHCVNTLGSFHCYKALTCE 799
Query: 148 PGFTLSNDGRTCLGLKLGWGV-SCQA---CPAQGSELYAVL---CPEGPSKDNGG--ADI 198
PG+ L DG + G +CQ C Y C +G +D G DI
Sbjct: 800 PGYALK-DGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDI 858
Query: 199 NECTAVPGACPHG-SCENLEPGYRC-----ICDPGYHPDADGL-CRDIDECDMHQSYCAG 251
NECT++ C G SC N Y C IC GYH DG C D++EC+ C
Sbjct: 859 NECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGE 918
Query: 252 GQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
GQ C N GS+ C C G + + + C D++EC P R
Sbjct: 919 GQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWAS-------------------PGRL 959
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRC-----LDNRRGS--CWRRVVDGQCE 363
C + C NT G + C C G++L A +RC + +R S C QC
Sbjct: 960 -----CQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCY 1013
Query: 364 AAAPELLLRQ--------ECCCSVGL--AWGSXXXXXXXXXXXXXKGFAKL-DGATCRDV 412
L EC G+ + +G+ +G +C+DV
Sbjct: 1014 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDV 1073
Query: 413 DECALSAELCA-GGTCVNTDGSYRC---DCPP 440
DECAL C+ TC N GS+RC +CPP
Sbjct: 1074 DECALGTHNCSEAETCHNIQGSFRCLRFECPP 1105
Score = 123 bits (297), Expect = 1e-27
Identities = 135/493 (27%), Positives = 179/493 (36%), Gaps = 86/493 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C + +C N G + C C PG+ +G CR + P + ++
Sbjct: 613 GELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRP-EGHPPQPEAPQEPALKSEFSQVAS 670
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
P P + C + CK C GS C C GY A +C D DE
Sbjct: 671 NTIPLPLP-------QPNTCKDNGPCK-QVCSTVGGSAICSCFPGYAIMADGVSCEDQDE 722
Query: 124 C--EEQRVCRNGRCHNTPGSFRCE-----CLPGFTLSNDGRTCLGLK--------LGWGV 168
C R C NT GSF C C G+ L N R C+G G
Sbjct: 723 CLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYIL-NAHRKCVGKNECVTDLHTCSRGE 781
Query: 169 SCQACPAQGSELYAVLCPEGPS-KDNGGADINECTAVPGACPHG-SCENLEPGYRC---- 222
C A+ C G + KD D++EC C G C+N + + C
Sbjct: 782 HCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ 841
Query: 223 ICDPGYHPDADGLCRDIDECDMHQSYCAGG-QCRNTAGSFTC-----VCPEGTRHEPELQ 276
C G+ D +G C DI+EC C G C NT GS+TC +C G +
Sbjct: 842 RCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGA 901
Query: 277 LCRDIDECE------GETET-HYIESDYERGDIPPTFPTRTELASPC--------DNGR- 320
C D++ECE GE + H + Y R D F R C GR
Sbjct: 902 KCVDVNECETGVHRCGEGQVCHNLPGSY-RCDCKAGF-QRDAFGRGCIDVNECWASPGRL 959
Query: 321 ----CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECC 376
C NT G + C C G++L A +RC D R C + +C
Sbjct: 960 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR------CSQECANIYGSYQCY 1013
Query: 377 CSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRC 436
C G DG TC D+DECA A + C+N GSY+C
Sbjct: 1014 CRQGYQLAE-------------------DGHTCTDIDECAQGAGILCTFRCLNVPGSYQC 1054
Query: 437 DCP-PGLTLDSTG 448
CP G T+ + G
Sbjct: 1055 ACPEQGYTMTANG 1067
Score = 105 bits (253), Expect = 2e-22
Identities = 126/439 (28%), Positives = 154/439 (35%), Gaps = 85/439 (19%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNS 97
D DEC P + C NT GSY C C PGF+ G + + S
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGR 157
E S Q P C D C++ C GS C C PG+ + DG
Sbjct: 664 EFS-QVASNTIPLPLPQPNTCKDNGPCKQV-------CSTVGGSAICSCFPGYAIMADGV 715
Query: 158 TCLGLK--LGWGVSC---QACPAQGSELY----AVLCPEG--PSKDNGGADINECTAVPG 206
+C L C Q C Y VLC +G + NEC
Sbjct: 716 SCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVGKNECVTDLH 775
Query: 207 ACPHGS-CENLEPGYRC----ICDPGYHPDADGLCRDIDECDMHQSYCAGG-QCRNTAGS 260
C G C N + C C+PGY DG C D+DEC M C G C+NT GS
Sbjct: 776 TCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDGECEDVDECAMGTHTCQPGFLCQNTKGS 834
Query: 261 FTCV----CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPC 316
F C C +G +PE C DI+EC T L+ PC
Sbjct: 835 FYCQARQRCMDGFLQDPEGN-CVDINEC-------------------------TSLSEPC 868
Query: 317 DNG-RCINTHGGFECE-----CELGYVLDATAQRCLD-NRRGSCWRRVVDGQCEAAAPEL 369
G CINT G + C+ C GY +C+D N + R +GQ L
Sbjct: 869 RPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQ---VCHNL 925
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + G C DV+EC S TC N
Sbjct: 926 PGSYRCDCKAGFQRDAF-------------------GRGCIDVNECWASPGRLCQHTCEN 966
Query: 430 TDGSYRCDCPPGLTLDSTG 448
T GSYRC C G L + G
Sbjct: 967 TLGSYRCSCASGFLLAADG 985
Score = 35.1 bits (77), Expect = 0.51
Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 1/44 (2%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCR 237
G D +EC +PG C N Y C C PG+ DG CR
Sbjct: 602 GDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCR 645
>AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 175 bits (425), Expect = 4e-43
Identities = 123/361 (34%), Positives = 162/361 (44%), Gaps = 46/361 (12%)
Query: 7 CTNGI-CKNIDGGFECI----CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGS 60
C+ G C N G F C C+PGY +G C DVDEC C+ G C+NT GS
Sbjct: 777 CSRGEHCVNTLGSFHCYKALTCEPGYAL-KDGE-CEDVDECAMGTHTCQPGFLCQNTKGS 834
Query: 61 YTCL----CEPGFAPTAAGYCADVDECAADSM-CKGG-RCVNSEGSFQC-----VCEAGY 109
+ C C GF G C D++EC + S C+ G C+N+ GS+ C +C GY
Sbjct: 835 FYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGY 894
Query: 110 RPTATRGACVDVDECEEQ-RVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW- 166
+ CVDV+ECE C G+ CHN PGS+RC+C GF GR C+ + W
Sbjct: 895 HASDDGXKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWA 954
Query: 167 --GVSCQACPAQGSELYAVLCPEG---PSKDNGGADINECTAVPGACPHGSCENLEPGYR 221
G CQ Y C G + D+NEC A C C N+ Y+
Sbjct: 955 SPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA--QRCSQ-ECANIYGSYQ 1011
Query: 222 CICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE-GTRHEPELQLCR 279
C C GY DG C DIDEC +C N GS+ C CPE G + C+
Sbjct: 1012 CYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCK 1071
Query: 280 DIDECE------GETET-HYIESDYE--RGDIPPTFPTRTELASPCDNGRCINTHGGFEC 330
D+DEC E ET H I+ + R + PP + ++ + C+ C H EC
Sbjct: 1072 DVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK--TKCERTTC---HDFLEC 1126
Query: 331 E 331
+
Sbjct: 1127 Q 1127
Score = 174 bits (423), Expect = 6e-43
Identities = 128/392 (32%), Positives = 170/392 (43%), Gaps = 51/392 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCRNTAGSY 61
+ G C +C + G C C PGY ++G C D DEC C RR C NT GS+
Sbjct: 685 DNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSF 743
Query: 62 TC-----LCEPGFAPTAAGYCADVDECAAD--SMCKGGRCVNSEGSFQC----VCEAGYR 110
C LC G+ A C D++EC D + +G CVN+ GSF C CE GY
Sbjct: 744 YCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY- 802
Query: 111 PTATRGACVDVDECE-EQRVCRNG-RCHNTPGSFRCE----CLPGFTLSNDGR------- 157
G C DVDEC C+ G C NT GSF C+ C+ GF +G
Sbjct: 803 -ALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINEC 861
Query: 158 TCLGLKLGWGVSC-QACPAQGSELYAVLCPEG-PSKDNGG--ADINECTAVPGACPHGS- 212
T L G SC + + ++C G + D+G D+NEC C G
Sbjct: 862 TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQV 921
Query: 213 CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
C NL YRC C G+ DA G C D++EC C NT GS+ C C G
Sbjct: 922 CHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL 981
Query: 272 EPELQLCRDIDECEGE---TETHYIESDYE----RG-DIPPTFPTRTELASPCDNG---- 319
+ + C D++ECE + E I Y+ +G + T T++ C G
Sbjct: 982 AADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDI-DECAQGAGIL 1040
Query: 320 ---RCINTHGGFECEC-ELGYVLDATAQRCLD 347
RC+N G ++C C E GY + A + C D
Sbjct: 1041 CTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1072
Score = 146 bits (354), Expect = 1e-34
Identities = 144/452 (31%), Positives = 186/452 (41%), Gaps = 82/452 (18%)
Query: 42 CRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADVDEC--AADSMCKGGRCVNSE 98
C+DN C++ C GS C C PG+A A G C D DEC A + CVN+
Sbjct: 683 CKDNGP-CKQV-CSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTL 740
Query: 99 GSFQCV-----CEAGYRPTATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRC----ECL 147
GSF CV C GY A R CVD++EC + C G C NT GSF C C
Sbjct: 741 GSFYCVNHTVLCADGYILNAHR-KCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCE 799
Query: 148 PGFTLSNDGRTCLGLKLGWGV-SCQA---CPAQGSELYAVL---CPEGPSKDNGG--ADI 198
PG+ L DG + G +CQ C Y C +G +D G DI
Sbjct: 800 PGYALK-DGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDI 858
Query: 199 NECTAVPGACPHG-SCENLEPGYRC-----ICDPGYHPDADGL-CRDIDECDMHQSYCAG 251
NECT++ C G SC N Y C IC GYH DG C D++EC+ C
Sbjct: 859 NECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGE 918
Query: 252 GQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
GQ C N GS+ C C G + + + C D++EC P R
Sbjct: 919 GQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWAS-------------------PGRL 959
Query: 311 ELASPCDNGRCINTHGGFECECELGYVLDATAQRC-----LDNRRGS--CWRRVVDGQCE 363
C + C NT G + C C G++L A +RC + +R S C QC
Sbjct: 960 -----CQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCY 1013
Query: 364 AAAPELLLRQ--------ECCCSVGL--AWGSXXXXXXXXXXXXXKGFAKL-DGATCRDV 412
L EC G+ + +G+ +G +C+DV
Sbjct: 1014 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDV 1073
Query: 413 DECALSAELCA-GGTCVNTDGSYRC---DCPP 440
DECAL C+ TC N GS+RC +CPP
Sbjct: 1074 DECALGTHNCSEAETCHNIQGSFRCLRFECPP 1105
Score = 122 bits (294), Expect = 3e-27
Identities = 134/493 (27%), Positives = 179/493 (36%), Gaps = 86/493 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C + +C N G + C C PG+ +G CR + P + ++
Sbjct: 613 GELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRP-EGHPPQPEAPQEPALKSEFSQVAS 670
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
P P + C + CK C GS C C GY A +C D DE
Sbjct: 671 NTIPLPLP-------QPNTCKDNGPCK-QVCSTVGGSAICSCFPGYAIMADGVSCEDQDE 722
Query: 124 C--EEQRVCRNGRCHNTPGSFRCE-----CLPGFTLSNDGRTCLGLK--------LGWGV 168
C R C NT GSF C C G+ L N R C+ + G
Sbjct: 723 CLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYIL-NAHRKCVDINECVTDLHTCSRGE 781
Query: 169 SCQACPAQGSELYAVLCPEGPS-KDNGGADINECTAVPGACPHG-SCENLEPGYRC---- 222
C A+ C G + KD D++EC C G C+N + + C
Sbjct: 782 HCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ 841
Query: 223 ICDPGYHPDADGLCRDIDECDMHQSYCAGG-QCRNTAGSFTC-----VCPEGTRHEPELQ 276
C G+ D +G C DI+EC C G C NT GS+TC +C G +
Sbjct: 842 RCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGX 901
Query: 277 LCRDIDECE------GETET-HYIESDYERGDIPPTFPTRTELASPC--------DNGR- 320
C D++ECE GE + H + Y R D F R C GR
Sbjct: 902 KCVDVNECETGVHRCGEGQVCHNLPGSY-RCDCKAGF-QRDAFGRGCIDVNECWASPGRL 959
Query: 321 ----CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECC 376
C NT G + C C G++L A +RC D R C + +C
Sbjct: 960 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR------CSQECANIYGSYQCY 1013
Query: 377 CSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRC 436
C G DG TC D+DECA A + C+N GSY+C
Sbjct: 1014 CRQGYQLAE-------------------DGHTCTDIDECAQGAGILCTFRCLNVPGSYQC 1054
Query: 437 DCP-PGLTLDSTG 448
CP G T+ + G
Sbjct: 1055 ACPEQGYTMTANG 1067
Score = 111 bits (267), Expect = 5e-24
Identities = 128/439 (29%), Positives = 156/439 (35%), Gaps = 85/439 (19%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNS 97
D DEC P + C NT GSY C C PGF+ G + + S
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGR 157
E S Q P C D C++ C GS C C PG+ + DG
Sbjct: 664 EFS-QVASNTIPLPLPQPNTCKDNGPCKQV-------CSTVGGSAICSCFPGYAIMADGV 715
Query: 158 TCLGLK--LGWGVSC---QACPAQGSELY----AVLCPEG--PSKDNGGADINECTAVPG 206
+C L C Q C Y VLC +G + DINEC
Sbjct: 716 SCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLH 775
Query: 207 ACPHGS-CENLEPGYRC----ICDPGYHPDADGLCRDIDECDMHQSYCAGG-QCRNTAGS 260
C G C N + C C+PGY DG C D+DEC M C G C+NT GS
Sbjct: 776 TCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDGECEDVDECAMGTHTCQPGFLCQNTKGS 834
Query: 261 FTCV----CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPC 316
F C C +G +PE C DI+EC T L+ PC
Sbjct: 835 FYCQARQRCMDGFLQDPEGN-CVDINEC-------------------------TSLSEPC 868
Query: 317 DNG-RCINTHGGFECE-----CELGYVLDATAQRCLD-NRRGSCWRRVVDGQCEAAAPEL 369
G CINT G + C+ C GY +C+D N + R +GQ L
Sbjct: 869 RPGFSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQ---VCHNL 925
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G + G C DV+EC S TC N
Sbjct: 926 PGSYRCDCKAGFQRDAF-------------------GRGCIDVNECWASPGRLCQHTCEN 966
Query: 430 TDGSYRCDCPPGLTLDSTG 448
T GSYRC C G L + G
Sbjct: 967 TLGSYRCSCASGFLLAADG 985
Score = 35.1 bits (77), Expect = 0.51
Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 1/44 (2%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCR 237
G D +EC +PG C N Y C C PG+ DG CR
Sbjct: 602 GDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCR 645
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 171 bits (415), Expect = 6e-42
Identities = 103/260 (39%), Positives = 127/260 (48%), Gaps = 21/260 (8%)
Query: 23 CKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADV 80
C G+ S G C D DEC NP C C N G+Y C C G A G C D+
Sbjct: 5093 CPSGFTLDSVGPFCADEDECAAGNP--CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 5149
Query: 81 DECAADS-MCKGGR-CVNSEGSFQCV--CEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
DECA C G+ C N+ GS++CV C +G+R T+ +C D++EC+E C RC
Sbjct: 5150 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCF 5208
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---QACP-AQGSELYAVLCPEGPSKD 192
N GSF C C PG+ L GR C+ + C Q C +G LCP G +K
Sbjct: 5209 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 5266
Query: 193 NGGA--DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSY 248
G DI+EC C + CEN YRC+C GY G C DIDEC+
Sbjct: 5267 ENGTCIDIDECKDGTHQCRYNQICENTRSSYRCVCPRGYRSQGVGRPCMDIDECEQVPKP 5326
Query: 249 CAGGQCRNTAGSFTCVCPEG 268
CA QC NT GSF C+CP G
Sbjct: 5327 CAH-QCSNTPGSFKCICPPG 5345
Score = 165 bits (400), Expect = 4e-40
Identities = 99/279 (35%), Positives = 134/279 (48%), Gaps = 14/279 (5%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC--LCEPG 68
C N G F C C+PGY+ +G C DV+ECR N VCR + C+NT G Y C LC G
Sbjct: 5207 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNG 5262
Query: 69 FAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G C D+DEC + C+ + C N+ S++CVC GYR C+D+DECE+
Sbjct: 5263 MTKAENGTCIDIDECKDGTHQCRYNQICENTRSSYRCVCPRGYRSQGVGRPCMDIDECEQ 5322
Query: 127 -QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
+ C + +C NTPGSF+C C PG L DG++C GL+ Q + V
Sbjct: 5323 VPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5381
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
P + + S R C G D C DIDEC+ +
Sbjct: 5382 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD-TCVDIDECE-N 5439
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C +C+NT GS+ C+CP G + + C+DIDEC
Sbjct: 5440 TDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5477
Score = 151 bits (367), Expect = 4e-36
Identities = 119/374 (31%), Positives = 163/374 (43%), Gaps = 45/374 (12%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G C++ C N G + C C G ++G C+D+DEC C G+ C NT GSY
Sbjct: 5115 GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYR 5173
Query: 63 CL--CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C+ C GF T+ G C D++EC S C RC N+ GSF C CE GY+ + C+
Sbjct: 5174 CVVRCGSGFRRTSDGLSCQDINECQESSPCH-QRCFNAIGSFHCGCEPGYQLKGRK--CM 5230
Query: 120 DVDECEEQRVCR-NGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGV-SC---Q 171
DV+EC Q VCR + C NT G ++C C G T + +G TC+ + + G C Q
Sbjct: 5231 DVNEC-RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQ 5288
Query: 172 ACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
C S Y +CP G G DI+EC VP C H C N ++CIC PG
Sbjct: 5289 ICENTRSS-YRCVCPRGYRSQGVGRPCMDIDECEQVPKPCAH-QCSNTPGSFKCICPPGQ 5346
Query: 229 HPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPE--LQLCRDIDECE 285
H DG C ++ +Y N A F+ P ++P+ + +
Sbjct: 5347 HLLGDGKSCAGLERL---PNYGTQYSSYNLA-RFS---PVRNNYQPQQHYRQYSHLYSSY 5399
Query: 286 GETETHYIESDYERGDIPPTFPTRTELA-------SPCDN-----GRCINTHGGFECECE 333
E R I T P +E + C+N C NT G ++C C
Sbjct: 5400 SEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICP 5459
Query: 334 LGYVLDATAQRCLD 347
GY L + C D
Sbjct: 5460 PGYQLTHNGKTCQD 5473
Score = 135 bits (327), Expect = 3e-31
Identities = 87/232 (37%), Positives = 108/232 (46%), Gaps = 14/232 (6%)
Query: 65 CEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF + G +CAD DECAA + C C N+ G++ C C G A C D+DE
Sbjct: 5093 CPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5151
Query: 124 CEEQR-VCRNGR-CHNTPGSFRC--ECLPGFTLSNDGRTCLGLKLGWGVS-C-QACPAQG 177
C R C G+ C NT GS+RC C GF ++DG +C + S C Q C
Sbjct: 5152 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAI 5211
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCI--CDPGYHPDADG 234
+ P K D+NEC C P C+N GY+CI C G +G
Sbjct: 5212 GSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5269
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C DIDEC C Q C NT S+ CVCP G R + + C DIDECE
Sbjct: 5270 TCIDIDECKDGTHQCRYNQICENTRSSYRCVCPRGYRSQGVGRPCMDIDECE 5321
Score = 124 bits (298), Expect = 9e-28
Identities = 83/280 (29%), Positives = 121/280 (43%), Gaps = 21/280 (7%)
Query: 12 CKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
CKN GG++CI C G G C D+DEC+D CR + C NT SY C+C G
Sbjct: 5246 CKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRSSYRCVCPRG 5304
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+ G C D+DEC +C N+ GSF+C+C G +C ++
Sbjct: 5305 YRSQGVGRPCMDIDECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE----- 5359
Query: 128 RVCRNGRCHNTPGSFRCECLPG-FTLSNDGRTCLGLKLGWGV--SCQACPAQGSELYAVL 184
R+ G +++ R + + R L + + + ++
Sbjct: 5360 RLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKT 5419
Query: 185 CPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDEC 242
CPEG + DI+EC AC H C+N Y+CIC PGY +G C+DIDEC
Sbjct: 5420 CPEGSEASHDTCVDIDECENTD-ACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5477
Query: 243 DMHQSYCAGGQ-CRNTAGSFTCV---CPEGTRHEPELQLC 278
+C + C N GS+ C+ CP + +P C
Sbjct: 5478 LEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5517
Score = 102 bits (244), Expect = 3e-21
Identities = 87/280 (31%), Positives = 121/280 (43%), Gaps = 40/280 (14%)
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S+G C +G+ + C D DEC C + CHN G++ C C G T++ DG
Sbjct: 5085 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADG 5143
Query: 157 RTCLGL-KLGWG-VSCQA---CP-AQGSELYAVLCPEGPSKDNGG---ADINECTAVPGA 207
RTC + + G +C A C GS V C G + + G DINEC
Sbjct: 5144 RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSP 5202
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV-- 264
C H C N + C C+PGY C D++EC Q+ C Q C+NT G + C+
Sbjct: 5203 C-HQRCFNAIGSFHCGCEPGYQLKG-RKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDL 5258
Query: 265 CPEGTRHEPELQLCRDIDEC-EGETETHY------IESDYERGDIPPTFPTR-------- 309
CP G + E C DIDEC +G + Y S Y R P + ++
Sbjct: 5259 CPNGMT-KAENGTCIDIDECKDGTHQCRYNQICENTRSSY-RCVCPRGYRSQGVGRPCMD 5316
Query: 310 ----TELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
++ PC + +C NT G F+C C G L + C
Sbjct: 5317 IDECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSC 5355
Score = 67.7 bits (158), Expect = 8e-11
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV-C-RNGR 134
C D+DEC C+ C N+ GS+QC+C GY+ T C D+DEC EQ V C N
Sbjct: 5431 CVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5489
Query: 135 CHNTPGSFRC---ECLPGFTLSNDGRTCL 160
C N GS++C C P + CL
Sbjct: 5490 CFNMRGSYQCIDTPCPPNYQRDPVSGFCL 5518
Score = 49.6 bits (113), Expect = 2e-05
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 405 DGATCRDVDECALSAELC-AGGTCVNTDGSYRC--DCPPGLTLDSTG 448
DG TC+D+DECAL C AG C NT GSYRC C G S G
Sbjct: 5142 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDG 5188
Score = 44.4 bits (100), Expect = 8e-04
Identities = 20/43 (46%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D+DEC + CA C NT GS++C CPPG L G
Sbjct: 5311 GRPCMDIDECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDG 5352
Score = 44.0 bits (99), Expect = 0.001
Identities = 20/50 (40%), Positives = 22/50 (44%), Gaps = 1/50 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDSTG 448
G K + TC D+DEC C C NT SYRC CP G G
Sbjct: 5262 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRSSYRCVCPRGYRSQGVG 5311
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
TC D+DEC + + C C NT GSY+C CPPG L G
Sbjct: 5430 TCVDIDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNG 5468
Score = 41.5 bits (93), Expect = 0.006
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 24/132 (18%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
+PC + C N G + C C G + A + C D + R C A Q
Sbjct: 5116 NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHT----CHAG-------Q 5163
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDG 432
+C ++G GF + DG +C+D++EC S+ C N G
Sbjct: 5164 DCDNTIG---------SYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CHQRCFNAIG 5212
Query: 433 SYRCDCPPGLTL 444
S+ C C PG L
Sbjct: 5213 SFHCGCEPGYQL 5224
Score = 40.3 bits (90), Expect = 0.014
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D DECA + C+ +C N G+Y C CP GLT+ + G
Sbjct: 5103 GPFCADEDECA-AGNPCSH-SCHNAMGTYYCSCPKGLTIAADG 5143
Score = 36.7 bits (81), Expect = 0.17
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCPPGLTLD 445
+G TC+D+DEC C C N GSY+C CPP D
Sbjct: 5467 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5511
Score = 36.3 bits (80), Expect = 0.22
Identities = 53/198 (26%), Positives = 76/198 (38%), Gaps = 33/198 (16%)
Query: 265 CPEGTRHEPELQLCRDIDECE-GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
CP G + C D DEC G +H + G + P +A+ + I+
Sbjct: 5093 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHN--AMGTYYCSCPKGLTIAADGRTCQDID 5150
Query: 324 THGGFECECELGYVLDAT--AQRCLDNRRGSCWRRVVDG-------QCEAAAPELLLRQE 374
C G D T + RC+ R GS +RR DG +C+ ++P Q
Sbjct: 5151 ECALGRHTCHAGQDCDNTIGSYRCVV-RCGSGFRRTSDGLSCQDINECQESSP---CHQR 5206
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGS 433
C ++G G+ +L G C DV+EC +C C NT G
Sbjct: 5207 CFNAIG-----------SFHCGCEPGY-QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGG 5252
Query: 434 YRCD--CPPGLTLDSTGT 449
Y+C CP G+T GT
Sbjct: 5253 YKCIDLCPNGMTKAENGT 5270
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 168 bits (409), Expect = 3e-41
Identities = 102/260 (39%), Positives = 127/260 (48%), Gaps = 21/260 (8%)
Query: 23 CKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADV 80
C G+ S G C D DEC NP C C N G+Y C C G A G C D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP--CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 81 DECAADS-MCKGGR-CVNSEGSFQCV--CEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
DECA C G+ C N+ GS++CV C +G+R T+ +C D++EC+E C RC
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCF 5207
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---QACP-AQGSELYAVLCPEGPSKD 192
N GSF C C PG+ L GR C+ + C Q C +G LCP G +K
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 5265
Query: 193 NGGA--DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSY 248
G DI+EC C + CEN YRC+C GY G C DI+EC+
Sbjct: 5266 ENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKP 5325
Query: 249 CAGGQCRNTAGSFTCVCPEG 268
CA QC NT GSF C+CP G
Sbjct: 5326 CAH-QCSNTPGSFKCICPPG 5344
Score = 165 bits (401), Expect = 3e-40
Identities = 99/279 (35%), Positives = 135/279 (48%), Gaps = 14/279 (5%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC--LCEPG 68
C N G F C C+PGY+ +G C DV+ECR N VCR + C+NT G Y C LC G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 69 FAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G C D+DEC + C+ + C N+ GS++CVC GYR C+D++ECE+
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 127 -QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
+ C + +C NTPGSF+C C PG L DG++C GL+ Q + V
Sbjct: 5322 VPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
P + + S R C G D C DIDEC+ +
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD-TCVDIDECE-N 5438
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C +C+NT GS+ C+CP G + + C+DIDEC
Sbjct: 5439 TDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Score = 153 bits (371), Expect = 1e-36
Identities = 121/375 (32%), Positives = 165/375 (44%), Gaps = 47/375 (12%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G C++ C N G + C C G ++G C+D+DEC C G+ C NT GSY
Sbjct: 5114 GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYR 5172
Query: 63 CL--CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C+ C GF T+ G C D++EC S C RC N+ GSF C CE GY+ + C+
Sbjct: 5173 CVVRCGSGFRRTSDGLSCQDINECQESSPCH-QRCFNAIGSFHCGCEPGYQLKGRK--CM 5229
Query: 120 DVDECEEQRVCR-NGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGV-SC---Q 171
DV+EC Q VCR + C NT G ++C C G T + +G TC+ + + G C Q
Sbjct: 5230 DVNEC-RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQ 5287
Query: 172 ACP-AQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPG 227
C +GS Y +CP G G DINEC VP C H C N ++CIC PG
Sbjct: 5288 ICENTRGS--YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPG 5344
Query: 228 YHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPE--LQLCRDIDEC 284
H DG C ++ +Y N A F+ P ++P+ + +
Sbjct: 5345 QHLLGDGKSCAGLERL---PNYGTQYSSYNLA-RFS---PVRNNYQPQQHYRQYSHLYSS 5397
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELA-------SPCDN-----GRCINTHGGFECEC 332
E R I T P +E + C+N C NT G ++C C
Sbjct: 5398 YSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCIC 5457
Query: 333 ELGYVLDATAQRCLD 347
GY L + C D
Sbjct: 5458 PPGYQLTHNGKTCQD 5472
Score = 136 bits (328), Expect = 2e-31
Identities = 87/232 (37%), Positives = 109/232 (46%), Gaps = 14/232 (6%)
Query: 65 CEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF + G +CAD DECAA + C C N+ G++ C C G A C D+DE
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 124 CEEQR-VCRNGR-CHNTPGSFRC--ECLPGFTLSNDGRTCLGLKLGWGVS-C-QACPAQG 177
C R C G+ C NT GS+RC C GF ++DG +C + S C Q C
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAI 5210
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCI--CDPGYHPDADG 234
+ P K D+NEC C P C+N GY+CI C G +G
Sbjct: 5211 GSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C DIDEC C Q C NT GS+ CVCP G R + + C DI+ECE
Sbjct: 5269 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Score = 124 bits (299), Expect = 6e-28
Identities = 83/280 (29%), Positives = 122/280 (43%), Gaps = 21/280 (7%)
Query: 12 CKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
CKN GG++CI C G G C D+DEC+D CR + C NT GSY C+C G
Sbjct: 5245 CKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRG 5303
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+ G C D++EC +C N+ GSF+C+C G +C ++
Sbjct: 5304 YRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE----- 5358
Query: 128 RVCRNGRCHNTPGSFRCECLPG-FTLSNDGRTCLGLKLGWGV--SCQACPAQGSELYAVL 184
R+ G +++ R + + R L + + + ++
Sbjct: 5359 RLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKT 5418
Query: 185 CPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDEC 242
CPEG + DI+EC AC H C+N Y+CIC PGY +G C+DIDEC
Sbjct: 5419 CPEGSEASHDTCVDIDECENTD-ACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Query: 243 DMHQSYCAGGQ-CRNTAGSFTCV---CPEGTRHEPELQLC 278
+C + C N GS+ C+ CP + +P C
Sbjct: 5477 LEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 102 bits (244), Expect = 3e-21
Identities = 82/263 (31%), Positives = 110/263 (41%), Gaps = 43/263 (16%)
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S+G C +G+ + C D DEC C + CHN G++ C C G T++ DG
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADG 5142
Query: 157 RTCLGL-KLGWGV-SCQA---CPAQ-GSELYAVLCPEGPSKDNGGA---DINECTAVPGA 207
RTC + + G +C A C GS V C G + + G DINEC
Sbjct: 5143 RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSP 5201
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV-- 264
C H C N + C C+PGY C D++EC Q+ C Q C+NT G + C+
Sbjct: 5202 C-HQRCFNAIGSFHCGCEPGYQLKGRK-CMDVNEC--RQNVCRPDQHCKNTRGGYKCIDL 5257
Query: 265 CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT 324
CP G + E C DIDEC+ T + Y N C NT
Sbjct: 5258 CPNGMT-KAENGTCIDIDECKDGTH----QCRY--------------------NQICENT 5292
Query: 325 HGGFECECELGYVLDATAQRCLD 347
G + C C GY + C+D
Sbjct: 5293 RGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 67.7 bits (158), Expect = 8e-11
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV-C-RNGR 134
C D+DEC C+ C N+ GS+QC+C GY+ T C D+DEC EQ V C N
Sbjct: 5430 CVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 135 CHNTPGSFRC---ECLPGFTLSNDGRTCL 160
C N GS++C C P + CL
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFCL 5517
Score = 49.6 bits (113), Expect = 2e-05
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 405 DGATCRDVDECALSAELC-AGGTCVNTDGSYRC--DCPPGLTLDSTG 448
DG TC+D+DECAL C AG C NT GSYRC C G S G
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDG 5187
Score = 46.4 bits (105), Expect = 2e-04
Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDSTG 448
G K + TC D+DEC C C NT GSYRC CP G G
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG 5310
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
TC D+DEC + + C C NT GSY+C CPPG L G
Sbjct: 5429 TCVDIDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNG 5467
Score = 42.3 bits (95), Expect = 0.003
Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D++EC + CA C NT GS++C CPPG L G
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDG 5351
Score = 41.5 bits (93), Expect = 0.006
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 24/132 (18%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
+PC + C N G + C C G + A + C D + R C A Q
Sbjct: 5115 NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHT----CHAG-------Q 5162
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDG 432
+C ++G GF + DG +C+D++EC S+ C N G
Sbjct: 5163 DCDNTIG---------SYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CHQRCFNAIG 5211
Query: 433 SYRCDCPPGLTL 444
S+ C C PG L
Sbjct: 5212 SFHCGCEPGYQL 5223
Score = 40.3 bits (90), Expect = 0.014
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D DECA + C+ +C N G+Y C CP GLT+ + G
Sbjct: 5102 GPFCADEDECA-AGNPCSH-SCHNAMGTYYCSCPKGLTIAADG 5142
Score = 36.7 bits (81), Expect = 0.17
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCPPGLTLD 445
+G TC+D+DEC C C N GSY+C CPP D
Sbjct: 5466 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Score = 36.3 bits (80), Expect = 0.22
Identities = 53/198 (26%), Positives = 76/198 (38%), Gaps = 33/198 (16%)
Query: 265 CPEGTRHEPELQLCRDIDECE-GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
CP G + C D DEC G +H + G + P +A+ + I+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHN--AMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 324 THGGFECECELGYVLDAT--AQRCLDNRRGSCWRRVVDG-------QCEAAAPELLLRQE 374
C G D T + RC+ R GS +RR DG +C+ ++P Q
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVV-RCGSGFRRTSDGLSCQDINECQESSP---CHQR 5205
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGS 433
C ++G G+ +L G C DV+EC +C C NT G
Sbjct: 5206 CFNAIG-----------SFHCGCEPGY-QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGG 5251
Query: 434 YRCD--CPPGLTLDSTGT 449
Y+C CP G+T GT
Sbjct: 5252 YKCIDLCPNGMTKAENGT 5269
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 168 bits (409), Expect = 3e-41
Identities = 102/260 (39%), Positives = 127/260 (48%), Gaps = 21/260 (8%)
Query: 23 CKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADV 80
C G+ S G C D DEC NP C C N G+Y C C G A G C D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP--CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 81 DECAADS-MCKGGR-CVNSEGSFQCV--CEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
DECA C G+ C N+ GS++CV C +G+R T+ +C D++EC+E C RC
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCF 5207
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---QACP-AQGSELYAVLCPEGPSKD 192
N GSF C C PG+ L GR C+ + C Q C +G LCP G +K
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 5265
Query: 193 NGGA--DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSY 248
G DI+EC C + CEN YRC+C GY G C DI+EC+
Sbjct: 5266 ENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKP 5325
Query: 249 CAGGQCRNTAGSFTCVCPEG 268
CA QC NT GSF C+CP G
Sbjct: 5326 CAH-QCSNTPGSFKCICPPG 5344
Score = 165 bits (401), Expect = 3e-40
Identities = 99/279 (35%), Positives = 135/279 (48%), Gaps = 14/279 (5%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC--LCEPG 68
C N G F C C+PGY+ +G C DV+ECR N VCR + C+NT G Y C LC G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 69 FAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G C D+DEC + C+ + C N+ GS++CVC GYR C+D++ECE+
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 127 -QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
+ C + +C NTPGSF+C C PG L DG++C GL+ Q + V
Sbjct: 5322 VPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
P + + S R C G D C DIDEC+ +
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD-TCVDIDECE-N 5438
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C +C+NT GS+ C+CP G + + C+DIDEC
Sbjct: 5439 TDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Score = 153 bits (371), Expect = 1e-36
Identities = 121/375 (32%), Positives = 165/375 (44%), Gaps = 47/375 (12%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G C++ C N G + C C G ++G C+D+DEC C G+ C NT GSY
Sbjct: 5114 GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYR 5172
Query: 63 CL--CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C+ C GF T+ G C D++EC S C RC N+ GSF C CE GY+ + C+
Sbjct: 5173 CVVRCGSGFRRTSDGLSCQDINECQESSPCH-QRCFNAIGSFHCGCEPGYQLKGRK--CM 5229
Query: 120 DVDECEEQRVCR-NGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGV-SC---Q 171
DV+EC Q VCR + C NT G ++C C G T + +G TC+ + + G C Q
Sbjct: 5230 DVNEC-RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQ 5287
Query: 172 ACP-AQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPG 227
C +GS Y +CP G G DINEC VP C H C N ++CIC PG
Sbjct: 5288 ICENTRGS--YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPG 5344
Query: 228 YHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPE--LQLCRDIDEC 284
H DG C ++ +Y N A F+ P ++P+ + +
Sbjct: 5345 QHLLGDGKSCAGLERL---PNYGTQYSSYNLA-RFS---PVRNNYQPQQHYRQYSHLYSS 5397
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELA-------SPCDN-----GRCINTHGGFECEC 332
E R I T P +E + C+N C NT G ++C C
Sbjct: 5398 YSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCIC 5457
Query: 333 ELGYVLDATAQRCLD 347
GY L + C D
Sbjct: 5458 PPGYQLTHNGKTCQD 5472
Score = 136 bits (328), Expect = 2e-31
Identities = 87/232 (37%), Positives = 109/232 (46%), Gaps = 14/232 (6%)
Query: 65 CEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF + G +CAD DECAA + C C N+ G++ C C G A C D+DE
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 124 CEEQR-VCRNGR-CHNTPGSFRC--ECLPGFTLSNDGRTCLGLKLGWGVS-C-QACPAQG 177
C R C G+ C NT GS+RC C GF ++DG +C + S C Q C
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAI 5210
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCI--CDPGYHPDADG 234
+ P K D+NEC C P C+N GY+CI C G +G
Sbjct: 5211 GSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C DIDEC C Q C NT GS+ CVCP G R + + C DI+ECE
Sbjct: 5269 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Score = 124 bits (299), Expect = 6e-28
Identities = 83/280 (29%), Positives = 122/280 (43%), Gaps = 21/280 (7%)
Query: 12 CKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
CKN GG++CI C G G C D+DEC+D CR + C NT GSY C+C G
Sbjct: 5245 CKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRG 5303
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+ G C D++EC +C N+ GSF+C+C G +C ++
Sbjct: 5304 YRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE----- 5358
Query: 128 RVCRNGRCHNTPGSFRCECLPG-FTLSNDGRTCLGLKLGWGV--SCQACPAQGSELYAVL 184
R+ G +++ R + + R L + + + ++
Sbjct: 5359 RLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKT 5418
Query: 185 CPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDEC 242
CPEG + DI+EC AC H C+N Y+CIC PGY +G C+DIDEC
Sbjct: 5419 CPEGSEASHDTCVDIDECENTD-ACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Query: 243 DMHQSYCAGGQ-CRNTAGSFTCV---CPEGTRHEPELQLC 278
+C + C N GS+ C+ CP + +P C
Sbjct: 5477 LEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 102 bits (244), Expect = 3e-21
Identities = 82/263 (31%), Positives = 110/263 (41%), Gaps = 43/263 (16%)
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S+G C +G+ + C D DEC C + CHN G++ C C G T++ DG
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADG 5142
Query: 157 RTCLGL-KLGWGV-SCQA---CPAQ-GSELYAVLCPEGPSKDNGGA---DINECTAVPGA 207
RTC + + G +C A C GS V C G + + G DINEC
Sbjct: 5143 RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSP 5201
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV-- 264
C H C N + C C+PGY C D++EC Q+ C Q C+NT G + C+
Sbjct: 5202 C-HQRCFNAIGSFHCGCEPGYQLKGRK-CMDVNEC--RQNVCRPDQHCKNTRGGYKCIDL 5257
Query: 265 CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT 324
CP G + E C DIDEC+ T + Y N C NT
Sbjct: 5258 CPNGMT-KAENGTCIDIDECKDGTH----QCRY--------------------NQICENT 5292
Query: 325 HGGFECECELGYVLDATAQRCLD 347
G + C C GY + C+D
Sbjct: 5293 RGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 67.7 bits (158), Expect = 8e-11
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV-C-RNGR 134
C D+DEC C+ C N+ GS+QC+C GY+ T C D+DEC EQ V C N
Sbjct: 5430 CVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 135 CHNTPGSFRC---ECLPGFTLSNDGRTCL 160
C N GS++C C P + CL
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFCL 5517
Score = 49.6 bits (113), Expect = 2e-05
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 405 DGATCRDVDECALSAELC-AGGTCVNTDGSYRC--DCPPGLTLDSTG 448
DG TC+D+DECAL C AG C NT GSYRC C G S G
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDG 5187
Score = 46.4 bits (105), Expect = 2e-04
Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDSTG 448
G K + TC D+DEC C C NT GSYRC CP G G
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG 5310
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
TC D+DEC + + C C NT GSY+C CPPG L G
Sbjct: 5429 TCVDIDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNG 5467
Score = 42.3 bits (95), Expect = 0.003
Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D++EC + CA C NT GS++C CPPG L G
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDG 5351
Score = 41.5 bits (93), Expect = 0.006
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 24/132 (18%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
+PC + C N G + C C G + A + C D + R C A Q
Sbjct: 5115 NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHT----CHAG-------Q 5162
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDG 432
+C ++G GF + DG +C+D++EC S+ C N G
Sbjct: 5163 DCDNTIG---------SYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CHQRCFNAIG 5211
Query: 433 SYRCDCPPGLTL 444
S+ C C PG L
Sbjct: 5212 SFHCGCEPGYQL 5223
Score = 40.3 bits (90), Expect = 0.014
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D DECA + C+ +C N G+Y C CP GLT+ + G
Sbjct: 5102 GPFCADEDECA-AGNPCSH-SCHNAMGTYYCSCPKGLTIAADG 5142
Score = 36.7 bits (81), Expect = 0.17
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCPPGLTLD 445
+G TC+D+DEC C C N GSY+C CPP D
Sbjct: 5466 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Score = 36.3 bits (80), Expect = 0.22
Identities = 53/198 (26%), Positives = 76/198 (38%), Gaps = 33/198 (16%)
Query: 265 CPEGTRHEPELQLCRDIDECE-GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
CP G + C D DEC G +H + G + P +A+ + I+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHN--AMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 324 THGGFECECELGYVLDAT--AQRCLDNRRGSCWRRVVDG-------QCEAAAPELLLRQE 374
C G D T + RC+ R GS +RR DG +C+ ++P Q
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVV-RCGSGFRRTSDGLSCQDINECQESSP---CHQR 5205
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGS 433
C ++G G+ +L G C DV+EC +C C NT G
Sbjct: 5206 CFNAIG-----------SFHCGCEPGY-QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGG 5251
Query: 434 YRCD--CPPGLTLDSTGT 449
Y+C CP G+T GT
Sbjct: 5252 YKCIDLCPNGMTKAENGT 5269
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 168 bits (409), Expect = 3e-41
Identities = 102/260 (39%), Positives = 127/260 (48%), Gaps = 21/260 (8%)
Query: 23 CKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADV 80
C G+ S G C D DEC NP C C N G+Y C C G A G C D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP--CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 81 DECAADS-MCKGGR-CVNSEGSFQCV--CEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
DECA C G+ C N+ GS++CV C +G+R T+ +C D++EC+E C RC
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCF 5207
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---QACP-AQGSELYAVLCPEGPSKD 192
N GSF C C PG+ L GR C+ + C Q C +G LCP G +K
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 5265
Query: 193 NGGA--DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSY 248
G DI+EC C + CEN YRC+C GY G C DI+EC+
Sbjct: 5266 ENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKP 5325
Query: 249 CAGGQCRNTAGSFTCVCPEG 268
CA QC NT GSF C+CP G
Sbjct: 5326 CAH-QCSNTPGSFKCICPPG 5344
Score = 165 bits (401), Expect = 3e-40
Identities = 99/279 (35%), Positives = 135/279 (48%), Gaps = 14/279 (5%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC--LCEPG 68
C N G F C C+PGY+ +G C DV+ECR N VCR + C+NT G Y C LC G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 69 FAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G C D+DEC + C+ + C N+ GS++CVC GYR C+D++ECE+
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 127 -QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
+ C + +C NTPGSF+C C PG L DG++C GL+ Q + V
Sbjct: 5322 VPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
P + + S R C G D C DIDEC+ +
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD-TCVDIDECE-N 5438
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C +C+NT GS+ C+CP G + + C+DIDEC
Sbjct: 5439 TDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Score = 153 bits (371), Expect = 1e-36
Identities = 121/375 (32%), Positives = 165/375 (44%), Gaps = 47/375 (12%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G C++ C N G + C C G ++G C+D+DEC C G+ C NT GSY
Sbjct: 5114 GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYR 5172
Query: 63 CL--CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C+ C GF T+ G C D++EC S C RC N+ GSF C CE GY+ + C+
Sbjct: 5173 CVVRCGSGFRRTSDGLSCQDINECQESSPCH-QRCFNAIGSFHCGCEPGYQLKGRK--CM 5229
Query: 120 DVDECEEQRVCR-NGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGV-SC---Q 171
DV+EC Q VCR + C NT G ++C C G T + +G TC+ + + G C Q
Sbjct: 5230 DVNEC-RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQ 5287
Query: 172 ACP-AQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPG 227
C +GS Y +CP G G DINEC VP C H C N ++CIC PG
Sbjct: 5288 ICENTRGS--YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPG 5344
Query: 228 YHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPE--LQLCRDIDEC 284
H DG C ++ +Y N A F+ P ++P+ + +
Sbjct: 5345 QHLLGDGKSCAGLERL---PNYGTQYSSYNLA-RFS---PVRNNYQPQQHYRQYSHLYSS 5397
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELA-------SPCDN-----GRCINTHGGFECEC 332
E R I T P +E + C+N C NT G ++C C
Sbjct: 5398 YSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCIC 5457
Query: 333 ELGYVLDATAQRCLD 347
GY L + C D
Sbjct: 5458 PPGYQLTHNGKTCQD 5472
Score = 136 bits (328), Expect = 2e-31
Identities = 87/232 (37%), Positives = 109/232 (46%), Gaps = 14/232 (6%)
Query: 65 CEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF + G +CAD DECAA + C C N+ G++ C C G A C D+DE
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 124 CEEQR-VCRNGR-CHNTPGSFRC--ECLPGFTLSNDGRTCLGLKLGWGVS-C-QACPAQG 177
C R C G+ C NT GS+RC C GF ++DG +C + S C Q C
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAI 5210
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCI--CDPGYHPDADG 234
+ P K D+NEC C P C+N GY+CI C G +G
Sbjct: 5211 GSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C DIDEC C Q C NT GS+ CVCP G R + + C DI+ECE
Sbjct: 5269 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Score = 124 bits (299), Expect = 6e-28
Identities = 83/280 (29%), Positives = 122/280 (43%), Gaps = 21/280 (7%)
Query: 12 CKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
CKN GG++CI C G G C D+DEC+D CR + C NT GSY C+C G
Sbjct: 5245 CKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRG 5303
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+ G C D++EC +C N+ GSF+C+C G +C ++
Sbjct: 5304 YRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE----- 5358
Query: 128 RVCRNGRCHNTPGSFRCECLPG-FTLSNDGRTCLGLKLGWGV--SCQACPAQGSELYAVL 184
R+ G +++ R + + R L + + + ++
Sbjct: 5359 RLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKT 5418
Query: 185 CPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDEC 242
CPEG + DI+EC AC H C+N Y+CIC PGY +G C+DIDEC
Sbjct: 5419 CPEGSEASHDTCVDIDECENTD-ACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Query: 243 DMHQSYCAGGQ-CRNTAGSFTCV---CPEGTRHEPELQLC 278
+C + C N GS+ C+ CP + +P C
Sbjct: 5477 LEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 102 bits (244), Expect = 3e-21
Identities = 82/263 (31%), Positives = 110/263 (41%), Gaps = 43/263 (16%)
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S+G C +G+ + C D DEC C + CHN G++ C C G T++ DG
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADG 5142
Query: 157 RTCLGL-KLGWGV-SCQA---CPAQ-GSELYAVLCPEGPSKDNGGA---DINECTAVPGA 207
RTC + + G +C A C GS V C G + + G DINEC
Sbjct: 5143 RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSP 5201
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV-- 264
C H C N + C C+PGY C D++EC Q+ C Q C+NT G + C+
Sbjct: 5202 C-HQRCFNAIGSFHCGCEPGYQLKGRK-CMDVNEC--RQNVCRPDQHCKNTRGGYKCIDL 5257
Query: 265 CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT 324
CP G + E C DIDEC+ T + Y N C NT
Sbjct: 5258 CPNGMT-KAENGTCIDIDECKDGTH----QCRY--------------------NQICENT 5292
Query: 325 HGGFECECELGYVLDATAQRCLD 347
G + C C GY + C+D
Sbjct: 5293 RGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 67.7 bits (158), Expect = 8e-11
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV-C-RNGR 134
C D+DEC C+ C N+ GS+QC+C GY+ T C D+DEC EQ V C N
Sbjct: 5430 CVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 135 CHNTPGSFRC---ECLPGFTLSNDGRTCL 160
C N GS++C C P + CL
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFCL 5517
Score = 49.6 bits (113), Expect = 2e-05
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 405 DGATCRDVDECALSAELC-AGGTCVNTDGSYRC--DCPPGLTLDSTG 448
DG TC+D+DECAL C AG C NT GSYRC C G S G
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDG 5187
Score = 46.4 bits (105), Expect = 2e-04
Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDSTG 448
G K + TC D+DEC C C NT GSYRC CP G G
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG 5310
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
TC D+DEC + + C C NT GSY+C CPPG L G
Sbjct: 5429 TCVDIDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNG 5467
Score = 42.3 bits (95), Expect = 0.003
Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D++EC + CA C NT GS++C CPPG L G
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDG 5351
Score = 41.5 bits (93), Expect = 0.006
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 24/132 (18%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
+PC + C N G + C C G + A + C D + R C A Q
Sbjct: 5115 NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHT----CHAG-------Q 5162
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDG 432
+C ++G GF + DG +C+D++EC S+ C N G
Sbjct: 5163 DCDNTIG---------SYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CHQRCFNAIG 5211
Query: 433 SYRCDCPPGLTL 444
S+ C C PG L
Sbjct: 5212 SFHCGCEPGYQL 5223
Score = 40.3 bits (90), Expect = 0.014
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D DECA + C+ +C N G+Y C CP GLT+ + G
Sbjct: 5102 GPFCADEDECA-AGNPCSH-SCHNAMGTYYCSCPKGLTIAADG 5142
Score = 36.7 bits (81), Expect = 0.17
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCPPGLTLD 445
+G TC+D+DEC C C N GSY+C CPP D
Sbjct: 5466 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Score = 36.3 bits (80), Expect = 0.22
Identities = 53/198 (26%), Positives = 76/198 (38%), Gaps = 33/198 (16%)
Query: 265 CPEGTRHEPELQLCRDIDECE-GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
CP G + C D DEC G +H + G + P +A+ + I+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHN--AMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 324 THGGFECECELGYVLDAT--AQRCLDNRRGSCWRRVVDG-------QCEAAAPELLLRQE 374
C G D T + RC+ R GS +RR DG +C+ ++P Q
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVV-RCGSGFRRTSDGLSCQDINECQESSP---CHQR 5205
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGS 433
C ++G G+ +L G C DV+EC +C C NT G
Sbjct: 5206 CFNAIG-----------SFHCGCEPGY-QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGG 5251
Query: 434 YRCD--CPPGLTLDSTGT 449
Y+C CP G+T GT
Sbjct: 5252 YKCIDLCPNGMTKAENGT 5269
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 168 bits (409), Expect = 3e-41
Identities = 102/260 (39%), Positives = 127/260 (48%), Gaps = 21/260 (8%)
Query: 23 CKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADV 80
C G+ S G C D DEC NP C C N G+Y C C G A G C D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP--CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 81 DECAADS-MCKGGR-CVNSEGSFQCV--CEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
DECA C G+ C N+ GS++CV C +G+R T+ +C D++EC+E C RC
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCF 5207
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---QACP-AQGSELYAVLCPEGPSKD 192
N GSF C C PG+ L GR C+ + C Q C +G LCP G +K
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 5265
Query: 193 NGGA--DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSY 248
G DI+EC C + CEN YRC+C GY G C DI+EC+
Sbjct: 5266 ENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKP 5325
Query: 249 CAGGQCRNTAGSFTCVCPEG 268
CA QC NT GSF C+CP G
Sbjct: 5326 CAH-QCSNTPGSFKCICPPG 5344
Score = 165 bits (401), Expect = 3e-40
Identities = 99/279 (35%), Positives = 135/279 (48%), Gaps = 14/279 (5%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC--LCEPG 68
C N G F C C+PGY+ +G C DV+ECR N VCR + C+NT G Y C LC G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 69 FAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G C D+DEC + C+ + C N+ GS++CVC GYR C+D++ECE+
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 127 -QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
+ C + +C NTPGSF+C C PG L DG++C GL+ Q + V
Sbjct: 5322 VPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
P + + S R C G D C DIDEC+ +
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD-TCVDIDECE-N 5438
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C +C+NT GS+ C+CP G + + C+DIDEC
Sbjct: 5439 TDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Score = 153 bits (371), Expect = 1e-36
Identities = 121/375 (32%), Positives = 165/375 (44%), Gaps = 47/375 (12%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G C++ C N G + C C G ++G C+D+DEC C G+ C NT GSY
Sbjct: 5114 GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYR 5172
Query: 63 CL--CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C+ C GF T+ G C D++EC S C RC N+ GSF C CE GY+ + C+
Sbjct: 5173 CVVRCGSGFRRTSDGLSCQDINECQESSPCH-QRCFNAIGSFHCGCEPGYQLKGRK--CM 5229
Query: 120 DVDECEEQRVCR-NGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGV-SC---Q 171
DV+EC Q VCR + C NT G ++C C G T + +G TC+ + + G C Q
Sbjct: 5230 DVNEC-RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQ 5287
Query: 172 ACP-AQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPG 227
C +GS Y +CP G G DINEC VP C H C N ++CIC PG
Sbjct: 5288 ICENTRGS--YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPG 5344
Query: 228 YHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPE--LQLCRDIDEC 284
H DG C ++ +Y N A F+ P ++P+ + +
Sbjct: 5345 QHLLGDGKSCAGLERL---PNYGTQYSSYNLA-RFS---PVRNNYQPQQHYRQYSHLYSS 5397
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELA-------SPCDN-----GRCINTHGGFECEC 332
E R I T P +E + C+N C NT G ++C C
Sbjct: 5398 YSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCIC 5457
Query: 333 ELGYVLDATAQRCLD 347
GY L + C D
Sbjct: 5458 PPGYQLTHNGKTCQD 5472
Score = 136 bits (328), Expect = 2e-31
Identities = 87/232 (37%), Positives = 109/232 (46%), Gaps = 14/232 (6%)
Query: 65 CEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF + G +CAD DECAA + C C N+ G++ C C G A C D+DE
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 124 CEEQR-VCRNGR-CHNTPGSFRC--ECLPGFTLSNDGRTCLGLKLGWGVS-C-QACPAQG 177
C R C G+ C NT GS+RC C GF ++DG +C + S C Q C
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAI 5210
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCI--CDPGYHPDADG 234
+ P K D+NEC C P C+N GY+CI C G +G
Sbjct: 5211 GSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C DIDEC C Q C NT GS+ CVCP G R + + C DI+ECE
Sbjct: 5269 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Score = 124 bits (299), Expect = 6e-28
Identities = 83/280 (29%), Positives = 122/280 (43%), Gaps = 21/280 (7%)
Query: 12 CKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
CKN GG++CI C G G C D+DEC+D CR + C NT GSY C+C G
Sbjct: 5245 CKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRG 5303
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+ G C D++EC +C N+ GSF+C+C G +C ++
Sbjct: 5304 YRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE----- 5358
Query: 128 RVCRNGRCHNTPGSFRCECLPG-FTLSNDGRTCLGLKLGWGV--SCQACPAQGSELYAVL 184
R+ G +++ R + + R L + + + ++
Sbjct: 5359 RLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKT 5418
Query: 185 CPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDEC 242
CPEG + DI+EC AC H C+N Y+CIC PGY +G C+DIDEC
Sbjct: 5419 CPEGSEASHDTCVDIDECENTD-ACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Query: 243 DMHQSYCAGGQ-CRNTAGSFTCV---CPEGTRHEPELQLC 278
+C + C N GS+ C+ CP + +P C
Sbjct: 5477 LEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 102 bits (244), Expect = 3e-21
Identities = 82/263 (31%), Positives = 110/263 (41%), Gaps = 43/263 (16%)
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S+G C +G+ + C D DEC C + CHN G++ C C G T++ DG
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADG 5142
Query: 157 RTCLGL-KLGWGV-SCQA---CPAQ-GSELYAVLCPEGPSKDNGGA---DINECTAVPGA 207
RTC + + G +C A C GS V C G + + G DINEC
Sbjct: 5143 RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSP 5201
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV-- 264
C H C N + C C+PGY C D++EC Q+ C Q C+NT G + C+
Sbjct: 5202 C-HQRCFNAIGSFHCGCEPGYQLKGRK-CMDVNEC--RQNVCRPDQHCKNTRGGYKCIDL 5257
Query: 265 CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT 324
CP G + E C DIDEC+ T + Y N C NT
Sbjct: 5258 CPNGMT-KAENGTCIDIDECKDGTH----QCRY--------------------NQICENT 5292
Query: 325 HGGFECECELGYVLDATAQRCLD 347
G + C C GY + C+D
Sbjct: 5293 RGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 67.7 bits (158), Expect = 8e-11
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV-C-RNGR 134
C D+DEC C+ C N+ GS+QC+C GY+ T C D+DEC EQ V C N
Sbjct: 5430 CVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 135 CHNTPGSFRC---ECLPGFTLSNDGRTCL 160
C N GS++C C P + CL
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFCL 5517
Score = 49.6 bits (113), Expect = 2e-05
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 405 DGATCRDVDECALSAELC-AGGTCVNTDGSYRC--DCPPGLTLDSTG 448
DG TC+D+DECAL C AG C NT GSYRC C G S G
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDG 5187
Score = 46.4 bits (105), Expect = 2e-04
Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDSTG 448
G K + TC D+DEC C C NT GSYRC CP G G
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG 5310
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
TC D+DEC + + C C NT GSY+C CPPG L G
Sbjct: 5429 TCVDIDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNG 5467
Score = 42.3 bits (95), Expect = 0.003
Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D++EC + CA C NT GS++C CPPG L G
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDG 5351
Score = 41.5 bits (93), Expect = 0.006
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 24/132 (18%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
+PC + C N G + C C G + A + C D + R C A Q
Sbjct: 5115 NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHT----CHAG-------Q 5162
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDG 432
+C ++G GF + DG +C+D++EC S+ C N G
Sbjct: 5163 DCDNTIG---------SYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CHQRCFNAIG 5211
Query: 433 SYRCDCPPGLTL 444
S+ C C PG L
Sbjct: 5212 SFHCGCEPGYQL 5223
Score = 40.3 bits (90), Expect = 0.014
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D DECA + C+ +C N G+Y C CP GLT+ + G
Sbjct: 5102 GPFCADEDECA-AGNPCSH-SCHNAMGTYYCSCPKGLTIAADG 5142
Score = 36.7 bits (81), Expect = 0.17
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCPPGLTLD 445
+G TC+D+DEC C C N GSY+C CPP D
Sbjct: 5466 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Score = 36.3 bits (80), Expect = 0.22
Identities = 53/198 (26%), Positives = 76/198 (38%), Gaps = 33/198 (16%)
Query: 265 CPEGTRHEPELQLCRDIDECE-GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
CP G + C D DEC G +H + G + P +A+ + I+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHN--AMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 324 THGGFECECELGYVLDAT--AQRCLDNRRGSCWRRVVDG-------QCEAAAPELLLRQE 374
C G D T + RC+ R GS +RR DG +C+ ++P Q
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVV-RCGSGFRRTSDGLSCQDINECQESSP---CHQR 5205
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGS 433
C ++G G+ +L G C DV+EC +C C NT G
Sbjct: 5206 CFNAIG-----------SFHCGCEPGY-QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGG 5251
Query: 434 YRCD--CPPGLTLDSTGT 449
Y+C CP G+T GT
Sbjct: 5252 YKCIDLCPNGMTKAENGT 5269
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 168 bits (409), Expect = 3e-41
Identities = 102/260 (39%), Positives = 127/260 (48%), Gaps = 21/260 (8%)
Query: 23 CKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADV 80
C G+ S G C D DEC NP C C N G+Y C C G A G C D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP--CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 81 DECAADS-MCKGGR-CVNSEGSFQCV--CEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
DECA C G+ C N+ GS++CV C +G+R T+ +C D++EC+E C RC
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCF 5207
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---QACP-AQGSELYAVLCPEGPSKD 192
N GSF C C PG+ L GR C+ + C Q C +G LCP G +K
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 5265
Query: 193 NGGA--DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSY 248
G DI+EC C + CEN YRC+C GY G C DI+EC+
Sbjct: 5266 ENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKP 5325
Query: 249 CAGGQCRNTAGSFTCVCPEG 268
CA QC NT GSF C+CP G
Sbjct: 5326 CAH-QCSNTPGSFKCICPPG 5344
Score = 165 bits (401), Expect = 3e-40
Identities = 99/279 (35%), Positives = 135/279 (48%), Gaps = 14/279 (5%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC--LCEPG 68
C N G F C C+PGY+ +G C DV+ECR N VCR + C+NT G Y C LC G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 69 FAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G C D+DEC + C+ + C N+ GS++CVC GYR C+D++ECE+
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 127 -QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
+ C + +C NTPGSF+C C PG L DG++C GL+ Q + V
Sbjct: 5322 VPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
P + + S R C G D C DIDEC+ +
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD-TCVDIDECE-N 5438
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C +C+NT GS+ C+CP G + + C+DIDEC
Sbjct: 5439 TDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Score = 153 bits (371), Expect = 1e-36
Identities = 121/375 (32%), Positives = 165/375 (44%), Gaps = 47/375 (12%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G C++ C N G + C C G ++G C+D+DEC C G+ C NT GSY
Sbjct: 5114 GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYR 5172
Query: 63 CL--CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C+ C GF T+ G C D++EC S C RC N+ GSF C CE GY+ + C+
Sbjct: 5173 CVVRCGSGFRRTSDGLSCQDINECQESSPCH-QRCFNAIGSFHCGCEPGYQLKGRK--CM 5229
Query: 120 DVDECEEQRVCR-NGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGV-SC---Q 171
DV+EC Q VCR + C NT G ++C C G T + +G TC+ + + G C Q
Sbjct: 5230 DVNEC-RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQ 5287
Query: 172 ACP-AQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPG 227
C +GS Y +CP G G DINEC VP C H C N ++CIC PG
Sbjct: 5288 ICENTRGS--YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPG 5344
Query: 228 YHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPE--LQLCRDIDEC 284
H DG C ++ +Y N A F+ P ++P+ + +
Sbjct: 5345 QHLLGDGKSCAGLERL---PNYGTQYSSYNLA-RFS---PVRNNYQPQQHYRQYSHLYSS 5397
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELA-------SPCDN-----GRCINTHGGFECEC 332
E R I T P +E + C+N C NT G ++C C
Sbjct: 5398 YSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCIC 5457
Query: 333 ELGYVLDATAQRCLD 347
GY L + C D
Sbjct: 5458 PPGYQLTHNGKTCQD 5472
Score = 136 bits (328), Expect = 2e-31
Identities = 87/232 (37%), Positives = 109/232 (46%), Gaps = 14/232 (6%)
Query: 65 CEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF + G +CAD DECAA + C C N+ G++ C C G A C D+DE
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 124 CEEQR-VCRNGR-CHNTPGSFRC--ECLPGFTLSNDGRTCLGLKLGWGVS-C-QACPAQG 177
C R C G+ C NT GS+RC C GF ++DG +C + S C Q C
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAI 5210
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCI--CDPGYHPDADG 234
+ P K D+NEC C P C+N GY+CI C G +G
Sbjct: 5211 GSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C DIDEC C Q C NT GS+ CVCP G R + + C DI+ECE
Sbjct: 5269 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Score = 124 bits (299), Expect = 6e-28
Identities = 83/280 (29%), Positives = 122/280 (43%), Gaps = 21/280 (7%)
Query: 12 CKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
CKN GG++CI C G G C D+DEC+D CR + C NT GSY C+C G
Sbjct: 5245 CKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRG 5303
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+ G C D++EC +C N+ GSF+C+C G +C ++
Sbjct: 5304 YRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE----- 5358
Query: 128 RVCRNGRCHNTPGSFRCECLPG-FTLSNDGRTCLGLKLGWGV--SCQACPAQGSELYAVL 184
R+ G +++ R + + R L + + + ++
Sbjct: 5359 RLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKT 5418
Query: 185 CPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDEC 242
CPEG + DI+EC AC H C+N Y+CIC PGY +G C+DIDEC
Sbjct: 5419 CPEGSEASHDTCVDIDECENTD-ACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Query: 243 DMHQSYCAGGQ-CRNTAGSFTCV---CPEGTRHEPELQLC 278
+C + C N GS+ C+ CP + +P C
Sbjct: 5477 LEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 102 bits (244), Expect = 3e-21
Identities = 82/263 (31%), Positives = 110/263 (41%), Gaps = 43/263 (16%)
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S+G C +G+ + C D DEC C + CHN G++ C C G T++ DG
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADG 5142
Query: 157 RTCLGL-KLGWGV-SCQA---CPAQ-GSELYAVLCPEGPSKDNGGA---DINECTAVPGA 207
RTC + + G +C A C GS V C G + + G DINEC
Sbjct: 5143 RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSP 5201
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV-- 264
C H C N + C C+PGY C D++EC Q+ C Q C+NT G + C+
Sbjct: 5202 C-HQRCFNAIGSFHCGCEPGYQLKGRK-CMDVNEC--RQNVCRPDQHCKNTRGGYKCIDL 5257
Query: 265 CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT 324
CP G + E C DIDEC+ T + Y N C NT
Sbjct: 5258 CPNGMT-KAENGTCIDIDECKDGTH----QCRY--------------------NQICENT 5292
Query: 325 HGGFECECELGYVLDATAQRCLD 347
G + C C GY + C+D
Sbjct: 5293 RGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 67.7 bits (158), Expect = 8e-11
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV-C-RNGR 134
C D+DEC C+ C N+ GS+QC+C GY+ T C D+DEC EQ V C N
Sbjct: 5430 CVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 135 CHNTPGSFRC---ECLPGFTLSNDGRTCL 160
C N GS++C C P + CL
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFCL 5517
Score = 49.6 bits (113), Expect = 2e-05
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 405 DGATCRDVDECALSAELC-AGGTCVNTDGSYRC--DCPPGLTLDSTG 448
DG TC+D+DECAL C AG C NT GSYRC C G S G
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDG 5187
Score = 46.4 bits (105), Expect = 2e-04
Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDSTG 448
G K + TC D+DEC C C NT GSYRC CP G G
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG 5310
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
TC D+DEC + + C C NT GSY+C CPPG L G
Sbjct: 5429 TCVDIDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNG 5467
Score = 42.3 bits (95), Expect = 0.003
Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D++EC + CA C NT GS++C CPPG L G
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDG 5351
Score = 41.5 bits (93), Expect = 0.006
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 24/132 (18%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
+PC + C N G + C C G + A + C D + R C A Q
Sbjct: 5115 NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHT----CHAG-------Q 5162
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDG 432
+C ++G GF + DG +C+D++EC S+ C N G
Sbjct: 5163 DCDNTIG---------SYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CHQRCFNAIG 5211
Query: 433 SYRCDCPPGLTL 444
S+ C C PG L
Sbjct: 5212 SFHCGCEPGYQL 5223
Score = 40.3 bits (90), Expect = 0.014
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D DECA + C+ +C N G+Y C CP GLT+ + G
Sbjct: 5102 GPFCADEDECA-AGNPCSH-SCHNAMGTYYCSCPKGLTIAADG 5142
Score = 36.7 bits (81), Expect = 0.17
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCPPGLTLD 445
+G TC+D+DEC C C N GSY+C CPP D
Sbjct: 5466 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Score = 36.3 bits (80), Expect = 0.22
Identities = 53/198 (26%), Positives = 76/198 (38%), Gaps = 33/198 (16%)
Query: 265 CPEGTRHEPELQLCRDIDECE-GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
CP G + C D DEC G +H + G + P +A+ + I+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHN--AMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 324 THGGFECECELGYVLDAT--AQRCLDNRRGSCWRRVVDG-------QCEAAAPELLLRQE 374
C G D T + RC+ R GS +RR DG +C+ ++P Q
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVV-RCGSGFRRTSDGLSCQDINECQESSP---CHQR 5205
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGS 433
C ++G G+ +L G C DV+EC +C C NT G
Sbjct: 5206 CFNAIG-----------SFHCGCEPGY-QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGG 5251
Query: 434 YRCD--CPPGLTLDSTGT 449
Y+C CP G+T GT
Sbjct: 5252 YKCIDLCPNGMTKAENGT 5269
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 168 bits (409), Expect = 3e-41
Identities = 102/260 (39%), Positives = 127/260 (48%), Gaps = 21/260 (8%)
Query: 23 CKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADV 80
C G+ S G C D DEC NP C C N G+Y C C G A G C D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP--CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 81 DECAADS-MCKGGR-CVNSEGSFQCV--CEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
DECA C G+ C N+ GS++CV C +G+R T+ +C D++EC+E C RC
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCF 5207
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---QACP-AQGSELYAVLCPEGPSKD 192
N GSF C C PG+ L GR C+ + C Q C +G LCP G +K
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 5265
Query: 193 NGGA--DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSY 248
G DI+EC C + CEN YRC+C GY G C DI+EC+
Sbjct: 5266 ENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKP 5325
Query: 249 CAGGQCRNTAGSFTCVCPEG 268
CA QC NT GSF C+CP G
Sbjct: 5326 CAH-QCSNTPGSFKCICPPG 5344
Score = 165 bits (401), Expect = 3e-40
Identities = 99/279 (35%), Positives = 135/279 (48%), Gaps = 14/279 (5%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC--LCEPG 68
C N G F C C+PGY+ +G C DV+ECR N VCR + C+NT G Y C LC G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 69 FAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G C D+DEC + C+ + C N+ GS++CVC GYR C+D++ECE+
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 127 -QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
+ C + +C NTPGSF+C C PG L DG++C GL+ Q + V
Sbjct: 5322 VPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
P + + S R C G D C DIDEC+ +
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD-TCVDIDECE-N 5438
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C +C+NT GS+ C+CP G + + C+DIDEC
Sbjct: 5439 TDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Score = 153 bits (371), Expect = 1e-36
Identities = 121/375 (32%), Positives = 165/375 (44%), Gaps = 47/375 (12%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G C++ C N G + C C G ++G C+D+DEC C G+ C NT GSY
Sbjct: 5114 GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYR 5172
Query: 63 CL--CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C+ C GF T+ G C D++EC S C RC N+ GSF C CE GY+ + C+
Sbjct: 5173 CVVRCGSGFRRTSDGLSCQDINECQESSPCH-QRCFNAIGSFHCGCEPGYQLKGRK--CM 5229
Query: 120 DVDECEEQRVCR-NGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGV-SC---Q 171
DV+EC Q VCR + C NT G ++C C G T + +G TC+ + + G C Q
Sbjct: 5230 DVNEC-RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQ 5287
Query: 172 ACP-AQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPG 227
C +GS Y +CP G G DINEC VP C H C N ++CIC PG
Sbjct: 5288 ICENTRGS--YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPG 5344
Query: 228 YHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPE--LQLCRDIDEC 284
H DG C ++ +Y N A F+ P ++P+ + +
Sbjct: 5345 QHLLGDGKSCAGLERL---PNYGTQYSSYNLA-RFS---PVRNNYQPQQHYRQYSHLYSS 5397
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELA-------SPCDN-----GRCINTHGGFECEC 332
E R I T P +E + C+N C NT G ++C C
Sbjct: 5398 YSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCIC 5457
Query: 333 ELGYVLDATAQRCLD 347
GY L + C D
Sbjct: 5458 PPGYQLTHNGKTCQD 5472
Score = 136 bits (328), Expect = 2e-31
Identities = 87/232 (37%), Positives = 109/232 (46%), Gaps = 14/232 (6%)
Query: 65 CEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF + G +CAD DECAA + C C N+ G++ C C G A C D+DE
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 124 CEEQR-VCRNGR-CHNTPGSFRC--ECLPGFTLSNDGRTCLGLKLGWGVS-C-QACPAQG 177
C R C G+ C NT GS+RC C GF ++DG +C + S C Q C
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAI 5210
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCI--CDPGYHPDADG 234
+ P K D+NEC C P C+N GY+CI C G +G
Sbjct: 5211 GSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C DIDEC C Q C NT GS+ CVCP G R + + C DI+ECE
Sbjct: 5269 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Score = 124 bits (299), Expect = 6e-28
Identities = 83/280 (29%), Positives = 122/280 (43%), Gaps = 21/280 (7%)
Query: 12 CKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
CKN GG++CI C G G C D+DEC+D CR + C NT GSY C+C G
Sbjct: 5245 CKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRG 5303
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+ G C D++EC +C N+ GSF+C+C G +C ++
Sbjct: 5304 YRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE----- 5358
Query: 128 RVCRNGRCHNTPGSFRCECLPG-FTLSNDGRTCLGLKLGWGV--SCQACPAQGSELYAVL 184
R+ G +++ R + + R L + + + ++
Sbjct: 5359 RLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKT 5418
Query: 185 CPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDEC 242
CPEG + DI+EC AC H C+N Y+CIC PGY +G C+DIDEC
Sbjct: 5419 CPEGSEASHDTCVDIDECENTD-ACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Query: 243 DMHQSYCAGGQ-CRNTAGSFTCV---CPEGTRHEPELQLC 278
+C + C N GS+ C+ CP + +P C
Sbjct: 5477 LEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 102 bits (244), Expect = 3e-21
Identities = 82/263 (31%), Positives = 110/263 (41%), Gaps = 43/263 (16%)
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S+G C +G+ + C D DEC C + CHN G++ C C G T++ DG
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADG 5142
Query: 157 RTCLGL-KLGWGV-SCQA---CPAQ-GSELYAVLCPEGPSKDNGGA---DINECTAVPGA 207
RTC + + G +C A C GS V C G + + G DINEC
Sbjct: 5143 RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSP 5201
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV-- 264
C H C N + C C+PGY C D++EC Q+ C Q C+NT G + C+
Sbjct: 5202 C-HQRCFNAIGSFHCGCEPGYQLKGRK-CMDVNEC--RQNVCRPDQHCKNTRGGYKCIDL 5257
Query: 265 CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT 324
CP G + E C DIDEC+ T + Y N C NT
Sbjct: 5258 CPNGMT-KAENGTCIDIDECKDGTH----QCRY--------------------NQICENT 5292
Query: 325 HGGFECECELGYVLDATAQRCLD 347
G + C C GY + C+D
Sbjct: 5293 RGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 67.7 bits (158), Expect = 8e-11
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV-C-RNGR 134
C D+DEC C+ C N+ GS+QC+C GY+ T C D+DEC EQ V C N
Sbjct: 5430 CVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 135 CHNTPGSFRC---ECLPGFTLSNDGRTCL 160
C N GS++C C P + CL
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFCL 5517
Score = 49.6 bits (113), Expect = 2e-05
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 405 DGATCRDVDECALSAELC-AGGTCVNTDGSYRC--DCPPGLTLDSTG 448
DG TC+D+DECAL C AG C NT GSYRC C G S G
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDG 5187
Score = 46.4 bits (105), Expect = 2e-04
Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDSTG 448
G K + TC D+DEC C C NT GSYRC CP G G
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG 5310
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
TC D+DEC + + C C NT GSY+C CPPG L G
Sbjct: 5429 TCVDIDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNG 5467
Score = 42.3 bits (95), Expect = 0.003
Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D++EC + CA C NT GS++C CPPG L G
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDG 5351
Score = 41.5 bits (93), Expect = 0.006
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 24/132 (18%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
+PC + C N G + C C G + A + C D + R C A Q
Sbjct: 5115 NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHT----CHAG-------Q 5162
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDG 432
+C ++G GF + DG +C+D++EC S+ C N G
Sbjct: 5163 DCDNTIG---------SYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CHQRCFNAIG 5211
Query: 433 SYRCDCPPGLTL 444
S+ C C PG L
Sbjct: 5212 SFHCGCEPGYQL 5223
Score = 40.3 bits (90), Expect = 0.014
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D DECA + C+ +C N G+Y C CP GLT+ + G
Sbjct: 5102 GPFCADEDECA-AGNPCSH-SCHNAMGTYYCSCPKGLTIAADG 5142
Score = 36.7 bits (81), Expect = 0.17
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCPPGLTLD 445
+G TC+D+DEC C C N GSY+C CPP D
Sbjct: 5466 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Score = 36.3 bits (80), Expect = 0.22
Identities = 53/198 (26%), Positives = 76/198 (38%), Gaps = 33/198 (16%)
Query: 265 CPEGTRHEPELQLCRDIDECE-GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
CP G + C D DEC G +H + G + P +A+ + I+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHN--AMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 324 THGGFECECELGYVLDAT--AQRCLDNRRGSCWRRVVDG-------QCEAAAPELLLRQE 374
C G D T + RC+ R GS +RR DG +C+ ++P Q
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVV-RCGSGFRRTSDGLSCQDINECQESSP---CHQR 5205
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGS 433
C ++G G+ +L G C DV+EC +C C NT G
Sbjct: 5206 CFNAIG-----------SFHCGCEPGY-QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGG 5251
Query: 434 YRCD--CPPGLTLDSTGT 449
Y+C CP G+T GT
Sbjct: 5252 YKCIDLCPNGMTKAENGT 5269
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 168 bits (409), Expect = 3e-41
Identities = 102/260 (39%), Positives = 127/260 (48%), Gaps = 21/260 (8%)
Query: 23 CKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADV 80
C G+ S G C D DEC NP C C N G+Y C C G A G C D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP--CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 81 DECAADS-MCKGGR-CVNSEGSFQCV--CEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
DECA C G+ C N+ GS++CV C +G+R T+ +C D++EC+E C RC
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCF 5207
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---QACP-AQGSELYAVLCPEGPSKD 192
N GSF C C PG+ L GR C+ + C Q C +G LCP G +K
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 5265
Query: 193 NGGA--DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSY 248
G DI+EC C + CEN YRC+C GY G C DI+EC+
Sbjct: 5266 ENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKP 5325
Query: 249 CAGGQCRNTAGSFTCVCPEG 268
CA QC NT GSF C+CP G
Sbjct: 5326 CAH-QCSNTPGSFKCICPPG 5344
Score = 165 bits (401), Expect = 3e-40
Identities = 99/279 (35%), Positives = 135/279 (48%), Gaps = 14/279 (5%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC--LCEPG 68
C N G F C C+PGY+ +G C DV+ECR N VCR + C+NT G Y C LC G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 69 FAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G C D+DEC + C+ + C N+ GS++CVC GYR C+D++ECE+
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 127 -QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
+ C + +C NTPGSF+C C PG L DG++C GL+ Q + V
Sbjct: 5322 VPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
P + + S R C G D C DIDEC+ +
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD-TCVDIDECE-N 5438
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C +C+NT GS+ C+CP G + + C+DIDEC
Sbjct: 5439 TDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Score = 153 bits (371), Expect = 1e-36
Identities = 121/375 (32%), Positives = 165/375 (44%), Gaps = 47/375 (12%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G C++ C N G + C C G ++G C+D+DEC C G+ C NT GSY
Sbjct: 5114 GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYR 5172
Query: 63 CL--CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C+ C GF T+ G C D++EC S C RC N+ GSF C CE GY+ + C+
Sbjct: 5173 CVVRCGSGFRRTSDGLSCQDINECQESSPCH-QRCFNAIGSFHCGCEPGYQLKGRK--CM 5229
Query: 120 DVDECEEQRVCR-NGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGV-SC---Q 171
DV+EC Q VCR + C NT G ++C C G T + +G TC+ + + G C Q
Sbjct: 5230 DVNEC-RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQ 5287
Query: 172 ACP-AQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPG 227
C +GS Y +CP G G DINEC VP C H C N ++CIC PG
Sbjct: 5288 ICENTRGS--YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPG 5344
Query: 228 YHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPE--LQLCRDIDEC 284
H DG C ++ +Y N A F+ P ++P+ + +
Sbjct: 5345 QHLLGDGKSCAGLERL---PNYGTQYSSYNLA-RFS---PVRNNYQPQQHYRQYSHLYSS 5397
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELA-------SPCDN-----GRCINTHGGFECEC 332
E R I T P +E + C+N C NT G ++C C
Sbjct: 5398 YSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCIC 5457
Query: 333 ELGYVLDATAQRCLD 347
GY L + C D
Sbjct: 5458 PPGYQLTHNGKTCQD 5472
Score = 136 bits (328), Expect = 2e-31
Identities = 87/232 (37%), Positives = 109/232 (46%), Gaps = 14/232 (6%)
Query: 65 CEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF + G +CAD DECAA + C C N+ G++ C C G A C D+DE
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 124 CEEQR-VCRNGR-CHNTPGSFRC--ECLPGFTLSNDGRTCLGLKLGWGVS-C-QACPAQG 177
C R C G+ C NT GS+RC C GF ++DG +C + S C Q C
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAI 5210
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCI--CDPGYHPDADG 234
+ P K D+NEC C P C+N GY+CI C G +G
Sbjct: 5211 GSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C DIDEC C Q C NT GS+ CVCP G R + + C DI+ECE
Sbjct: 5269 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Score = 124 bits (299), Expect = 6e-28
Identities = 83/280 (29%), Positives = 122/280 (43%), Gaps = 21/280 (7%)
Query: 12 CKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
CKN GG++CI C G G C D+DEC+D CR + C NT GSY C+C G
Sbjct: 5245 CKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRG 5303
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+ G C D++EC +C N+ GSF+C+C G +C ++
Sbjct: 5304 YRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE----- 5358
Query: 128 RVCRNGRCHNTPGSFRCECLPG-FTLSNDGRTCLGLKLGWGV--SCQACPAQGSELYAVL 184
R+ G +++ R + + R L + + + ++
Sbjct: 5359 RLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKT 5418
Query: 185 CPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDEC 242
CPEG + DI+EC AC H C+N Y+CIC PGY +G C+DIDEC
Sbjct: 5419 CPEGSEASHDTCVDIDECENTD-ACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Query: 243 DMHQSYCAGGQ-CRNTAGSFTCV---CPEGTRHEPELQLC 278
+C + C N GS+ C+ CP + +P C
Sbjct: 5477 LEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 102 bits (244), Expect = 3e-21
Identities = 82/263 (31%), Positives = 110/263 (41%), Gaps = 43/263 (16%)
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S+G C +G+ + C D DEC C + CHN G++ C C G T++ DG
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADG 5142
Query: 157 RTCLGL-KLGWGV-SCQA---CPAQ-GSELYAVLCPEGPSKDNGGA---DINECTAVPGA 207
RTC + + G +C A C GS V C G + + G DINEC
Sbjct: 5143 RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSP 5201
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV-- 264
C H C N + C C+PGY C D++EC Q+ C Q C+NT G + C+
Sbjct: 5202 C-HQRCFNAIGSFHCGCEPGYQLKGRK-CMDVNEC--RQNVCRPDQHCKNTRGGYKCIDL 5257
Query: 265 CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT 324
CP G + E C DIDEC+ T + Y N C NT
Sbjct: 5258 CPNGMT-KAENGTCIDIDECKDGTH----QCRY--------------------NQICENT 5292
Query: 325 HGGFECECELGYVLDATAQRCLD 347
G + C C GY + C+D
Sbjct: 5293 RGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 67.7 bits (158), Expect = 8e-11
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV-C-RNGR 134
C D+DEC C+ C N+ GS+QC+C GY+ T C D+DEC EQ V C N
Sbjct: 5430 CVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 135 CHNTPGSFRC---ECLPGFTLSNDGRTCL 160
C N GS++C C P + CL
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFCL 5517
Score = 49.6 bits (113), Expect = 2e-05
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 405 DGATCRDVDECALSAELC-AGGTCVNTDGSYRC--DCPPGLTLDSTG 448
DG TC+D+DECAL C AG C NT GSYRC C G S G
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDG 5187
Score = 46.4 bits (105), Expect = 2e-04
Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDSTG 448
G K + TC D+DEC C C NT GSYRC CP G G
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG 5310
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
TC D+DEC + + C C NT GSY+C CPPG L G
Sbjct: 5429 TCVDIDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNG 5467
Score = 42.3 bits (95), Expect = 0.003
Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D++EC + CA C NT GS++C CPPG L G
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDG 5351
Score = 41.5 bits (93), Expect = 0.006
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 24/132 (18%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
+PC + C N G + C C G + A + C D + R C A Q
Sbjct: 5115 NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHT----CHAG-------Q 5162
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDG 432
+C ++G GF + DG +C+D++EC S+ C N G
Sbjct: 5163 DCDNTIG---------SYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CHQRCFNAIG 5211
Query: 433 SYRCDCPPGLTL 444
S+ C C PG L
Sbjct: 5212 SFHCGCEPGYQL 5223
Score = 40.3 bits (90), Expect = 0.014
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D DECA + C+ +C N G+Y C CP GLT+ + G
Sbjct: 5102 GPFCADEDECA-AGNPCSH-SCHNAMGTYYCSCPKGLTIAADG 5142
Score = 36.7 bits (81), Expect = 0.17
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCPPGLTLD 445
+G TC+D+DEC C C N GSY+C CPP D
Sbjct: 5466 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Score = 36.3 bits (80), Expect = 0.22
Identities = 53/198 (26%), Positives = 76/198 (38%), Gaps = 33/198 (16%)
Query: 265 CPEGTRHEPELQLCRDIDECE-GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
CP G + C D DEC G +H + G + P +A+ + I+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHN--AMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 324 THGGFECECELGYVLDAT--AQRCLDNRRGSCWRRVVDG-------QCEAAAPELLLRQE 374
C G D T + RC+ R GS +RR DG +C+ ++P Q
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVV-RCGSGFRRTSDGLSCQDINECQESSP---CHQR 5205
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGS 433
C ++G G+ +L G C DV+EC +C C NT G
Sbjct: 5206 CFNAIG-----------SFHCGCEPGY-QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGG 5251
Query: 434 YRCD--CPPGLTLDSTGT 449
Y+C CP G+T GT
Sbjct: 5252 YKCIDLCPNGMTKAENGT 5269
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 168 bits (409), Expect = 3e-41
Identities = 102/260 (39%), Positives = 127/260 (48%), Gaps = 21/260 (8%)
Query: 23 CKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADV 80
C G+ S G C D DEC NP C C N G+Y C C G A G C D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP--CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 81 DECAADS-MCKGGR-CVNSEGSFQCV--CEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
DECA C G+ C N+ GS++CV C +G+R T+ +C D++EC+E C RC
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCF 5207
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---QACP-AQGSELYAVLCPEGPSKD 192
N GSF C C PG+ L GR C+ + C Q C +G LCP G +K
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 5265
Query: 193 NGGA--DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSY 248
G DI+EC C + CEN YRC+C GY G C DI+EC+
Sbjct: 5266 ENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKP 5325
Query: 249 CAGGQCRNTAGSFTCVCPEG 268
CA QC NT GSF C+CP G
Sbjct: 5326 CAH-QCSNTPGSFKCICPPG 5344
Score = 165 bits (401), Expect = 3e-40
Identities = 99/279 (35%), Positives = 135/279 (48%), Gaps = 14/279 (5%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC--LCEPG 68
C N G F C C+PGY+ +G C DV+ECR N VCR + C+NT G Y C LC G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 69 FAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G C D+DEC + C+ + C N+ GS++CVC GYR C+D++ECE+
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 127 -QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
+ C + +C NTPGSF+C C PG L DG++C GL+ Q + V
Sbjct: 5322 VPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
P + + S R C G D C DIDEC+ +
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD-TCVDIDECE-N 5438
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C +C+NT GS+ C+CP G + + C+DIDEC
Sbjct: 5439 TDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Score = 153 bits (371), Expect = 1e-36
Identities = 121/375 (32%), Positives = 165/375 (44%), Gaps = 47/375 (12%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G C++ C N G + C C G ++G C+D+DEC C G+ C NT GSY
Sbjct: 5114 GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYR 5172
Query: 63 CL--CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C+ C GF T+ G C D++EC S C RC N+ GSF C CE GY+ + C+
Sbjct: 5173 CVVRCGSGFRRTSDGLSCQDINECQESSPCH-QRCFNAIGSFHCGCEPGYQLKGRK--CM 5229
Query: 120 DVDECEEQRVCR-NGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGV-SC---Q 171
DV+EC Q VCR + C NT G ++C C G T + +G TC+ + + G C Q
Sbjct: 5230 DVNEC-RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQ 5287
Query: 172 ACP-AQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPG 227
C +GS Y +CP G G DINEC VP C H C N ++CIC PG
Sbjct: 5288 ICENTRGS--YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPG 5344
Query: 228 YHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPE--LQLCRDIDEC 284
H DG C ++ +Y N A F+ P ++P+ + +
Sbjct: 5345 QHLLGDGKSCAGLERL---PNYGTQYSSYNLA-RFS---PVRNNYQPQQHYRQYSHLYSS 5397
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELA-------SPCDN-----GRCINTHGGFECEC 332
E R I T P +E + C+N C NT G ++C C
Sbjct: 5398 YSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCIC 5457
Query: 333 ELGYVLDATAQRCLD 347
GY L + C D
Sbjct: 5458 PPGYQLTHNGKTCQD 5472
Score = 136 bits (328), Expect = 2e-31
Identities = 87/232 (37%), Positives = 109/232 (46%), Gaps = 14/232 (6%)
Query: 65 CEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF + G +CAD DECAA + C C N+ G++ C C G A C D+DE
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 124 CEEQR-VCRNGR-CHNTPGSFRC--ECLPGFTLSNDGRTCLGLKLGWGVS-C-QACPAQG 177
C R C G+ C NT GS+RC C GF ++DG +C + S C Q C
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAI 5210
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCI--CDPGYHPDADG 234
+ P K D+NEC C P C+N GY+CI C G +G
Sbjct: 5211 GSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C DIDEC C Q C NT GS+ CVCP G R + + C DI+ECE
Sbjct: 5269 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 5320
Score = 124 bits (299), Expect = 6e-28
Identities = 83/280 (29%), Positives = 122/280 (43%), Gaps = 21/280 (7%)
Query: 12 CKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
CKN GG++CI C G G C D+DEC+D CR + C NT GSY C+C G
Sbjct: 5245 CKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRG 5303
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+ G C D++EC +C N+ GSF+C+C G +C ++
Sbjct: 5304 YRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE----- 5358
Query: 128 RVCRNGRCHNTPGSFRCECLPG-FTLSNDGRTCLGLKLGWGV--SCQACPAQGSELYAVL 184
R+ G +++ R + + R L + + + ++
Sbjct: 5359 RLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKT 5418
Query: 185 CPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDEC 242
CPEG + DI+EC AC H C+N Y+CIC PGY +G C+DIDEC
Sbjct: 5419 CPEGSEASHDTCVDIDECENTD-ACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Query: 243 DMHQSYCAGGQ-CRNTAGSFTCV---CPEGTRHEPELQLC 278
+C + C N GS+ C+ CP + +P C
Sbjct: 5477 LEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 102 bits (244), Expect = 3e-21
Identities = 82/263 (31%), Positives = 110/263 (41%), Gaps = 43/263 (16%)
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S+G C +G+ + C D DEC C + CHN G++ C C G T++ DG
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADG 5142
Query: 157 RTCLGL-KLGWGV-SCQA---CPAQ-GSELYAVLCPEGPSKDNGGA---DINECTAVPGA 207
RTC + + G +C A C GS V C G + + G DINEC
Sbjct: 5143 RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSP 5201
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV-- 264
C H C N + C C+PGY C D++EC Q+ C Q C+NT G + C+
Sbjct: 5202 C-HQRCFNAIGSFHCGCEPGYQLKGRK-CMDVNEC--RQNVCRPDQHCKNTRGGYKCIDL 5257
Query: 265 CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT 324
CP G + E C DIDEC+ T + Y N C NT
Sbjct: 5258 CPNGMT-KAENGTCIDIDECKDGTH----QCRY--------------------NQICENT 5292
Query: 325 HGGFECECELGYVLDATAQRCLD 347
G + C C GY + C+D
Sbjct: 5293 RGSYRCVCPRGYRSQGVGRPCMD 5315
Score = 67.7 bits (158), Expect = 8e-11
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV-C-RNGR 134
C D+DEC C+ C N+ GS+QC+C GY+ T C D+DEC EQ V C N
Sbjct: 5430 CVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 135 CHNTPGSFRC---ECLPGFTLSNDGRTCL 160
C N GS++C C P + CL
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFCL 5517
Score = 49.6 bits (113), Expect = 2e-05
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 405 DGATCRDVDECALSAELC-AGGTCVNTDGSYRC--DCPPGLTLDSTG 448
DG TC+D+DECAL C AG C NT GSYRC C G S G
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDG 5187
Score = 46.4 bits (105), Expect = 2e-04
Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDSTG 448
G K + TC D+DEC C C NT GSYRC CP G G
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG 5310
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
TC D+DEC + + C C NT GSY+C CPPG L G
Sbjct: 5429 TCVDIDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNG 5467
Score = 42.3 bits (95), Expect = 0.003
Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D++EC + CA C NT GS++C CPPG L G
Sbjct: 5310 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDG 5351
Score = 41.5 bits (93), Expect = 0.006
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 24/132 (18%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
+PC + C N G + C C G + A + C D + R C A Q
Sbjct: 5115 NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHT----CHAG-------Q 5162
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDG 432
+C ++G GF + DG +C+D++EC S+ C N G
Sbjct: 5163 DCDNTIG---------SYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CHQRCFNAIG 5211
Query: 433 SYRCDCPPGLTL 444
S+ C C PG L
Sbjct: 5212 SFHCGCEPGYQL 5223
Score = 40.3 bits (90), Expect = 0.014
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D DECA + C+ +C N G+Y C CP GLT+ + G
Sbjct: 5102 GPFCADEDECA-AGNPCSH-SCHNAMGTYYCSCPKGLTIAADG 5142
Score = 36.7 bits (81), Expect = 0.17
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCPPGLTLD 445
+G TC+D+DEC C C N GSY+C CPP D
Sbjct: 5466 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Score = 36.3 bits (80), Expect = 0.22
Identities = 53/198 (26%), Positives = 76/198 (38%), Gaps = 33/198 (16%)
Query: 265 CPEGTRHEPELQLCRDIDECE-GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
CP G + C D DEC G +H + G + P +A+ + I+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHN--AMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 324 THGGFECECELGYVLDAT--AQRCLDNRRGSCWRRVVDG-------QCEAAAPELLLRQE 374
C G D T + RC+ R GS +RR DG +C+ ++P Q
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVV-RCGSGFRRTSDGLSCQDINECQESSP---CHQR 5205
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGS 433
C ++G G+ +L G C DV+EC +C C NT G
Sbjct: 5206 CFNAIG-----------SFHCGCEPGY-QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGG 5251
Query: 434 YRCD--CPPGLTLDSTGT 449
Y+C CP G+T GT
Sbjct: 5252 YKCIDLCPNGMTKAENGT 5269
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 168 bits (409), Expect = 3e-41
Identities = 102/260 (39%), Positives = 127/260 (48%), Gaps = 21/260 (8%)
Query: 23 CKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CADV 80
C G+ S G C D DEC NP C C N G+Y C C G A G C D+
Sbjct: 2130 CPSGFTLDSVGPFCADEDECAAGNP--CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 2186
Query: 81 DECAADS-MCKGGR-CVNSEGSFQCV--CEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
DECA C G+ C N+ GS++CV C +G+R T+ +C D++EC+E C RC
Sbjct: 2187 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCF 2245
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---QACP-AQGSELYAVLCPEGPSKD 192
N GSF C C PG+ L GR C+ + C Q C +G LCP G +K
Sbjct: 2246 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 2303
Query: 193 NGGA--DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSY 248
G DI+EC C + CEN YRC+C GY G C DI+EC+
Sbjct: 2304 ENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKP 2363
Query: 249 CAGGQCRNTAGSFTCVCPEG 268
CA QC NT GSF C+CP G
Sbjct: 2364 CAH-QCSNTPGSFKCICPPG 2382
Score = 165 bits (401), Expect = 3e-40
Identities = 99/279 (35%), Positives = 135/279 (48%), Gaps = 14/279 (5%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC--LCEPG 68
C N G F C C+PGY+ +G C DV+ECR N VCR + C+NT G Y C LC G
Sbjct: 2244 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNG 2299
Query: 69 FAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G C D+DEC + C+ + C N+ GS++CVC GYR C+D++ECE+
Sbjct: 2300 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 2359
Query: 127 -QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
+ C + +C NTPGSF+C C PG L DG++C GL+ Q + V
Sbjct: 2360 VPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 2418
Query: 186 PEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
P + + S R C G D C DIDEC+ +
Sbjct: 2419 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD-TCVDIDECE-N 2476
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C +C+NT GS+ C+CP G + + C+DIDEC
Sbjct: 2477 TDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 2514
Score = 153 bits (371), Expect = 1e-36
Identities = 121/375 (32%), Positives = 165/375 (44%), Gaps = 47/375 (12%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G C++ C N G + C C G ++G C+D+DEC C G+ C NT GSY
Sbjct: 2152 GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYR 2210
Query: 63 CL--CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C+ C GF T+ G C D++EC S C RC N+ GSF C CE GY+ + C+
Sbjct: 2211 CVVRCGSGFRRTSDGLSCQDINECQESSPCH-QRCFNAIGSFHCGCEPGYQLKGRK--CM 2267
Query: 120 DVDECEEQRVCR-NGRCHNTPGSFRC--ECLPGFTLSNDGRTCLGL-KLGWGV-SC---Q 171
DV+EC Q VCR + C NT G ++C C G T + +G TC+ + + G C Q
Sbjct: 2268 DVNEC-RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQ 2325
Query: 172 ACP-AQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPG 227
C +GS Y +CP G G DINEC VP C H C N ++CIC PG
Sbjct: 2326 ICENTRGS--YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPG 2382
Query: 228 YHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPE--LQLCRDIDEC 284
H DG C ++ +Y N A F+ P ++P+ + +
Sbjct: 2383 QHLLGDGKSCAGLERL---PNYGTQYSSYNLA-RFS---PVRNNYQPQQHYRQYSHLYSS 2435
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELA-------SPCDN-----GRCINTHGGFECEC 332
E R I T P +E + C+N C NT G ++C C
Sbjct: 2436 YSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCIC 2495
Query: 333 ELGYVLDATAQRCLD 347
GY L + C D
Sbjct: 2496 PPGYQLTHNGKTCQD 2510
Score = 136 bits (328), Expect = 2e-31
Identities = 87/232 (37%), Positives = 109/232 (46%), Gaps = 14/232 (6%)
Query: 65 CEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF + G +CAD DECAA + C C N+ G++ C C G A C D+DE
Sbjct: 2130 CPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDE 2188
Query: 124 CEEQR-VCRNGR-CHNTPGSFRC--ECLPGFTLSNDGRTCLGLKLGWGVS-C-QACPAQG 177
C R C G+ C NT GS+RC C GF ++DG +C + S C Q C
Sbjct: 2189 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAI 2248
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCI--CDPGYHPDADG 234
+ P K D+NEC C P C+N GY+CI C G +G
Sbjct: 2249 GSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 2306
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C DIDEC C Q C NT GS+ CVCP G R + + C DI+ECE
Sbjct: 2307 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECE 2358
Score = 124 bits (299), Expect = 6e-28
Identities = 83/280 (29%), Positives = 122/280 (43%), Gaps = 21/280 (7%)
Query: 12 CKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
CKN GG++CI C G G C D+DEC+D CR + C NT GSY C+C G
Sbjct: 2283 CKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRG 2341
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+ G C D++EC +C N+ GSF+C+C G +C ++
Sbjct: 2342 YRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE----- 2396
Query: 128 RVCRNGRCHNTPGSFRCECLPG-FTLSNDGRTCLGLKLGWGV--SCQACPAQGSELYAVL 184
R+ G +++ R + + R L + + + ++
Sbjct: 2397 RLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKT 2456
Query: 185 CPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDEC 242
CPEG + DI+EC AC H C+N Y+CIC PGY +G C+DIDEC
Sbjct: 2457 CPEGSEASHDTCVDIDECENTD-ACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 2514
Query: 243 DMHQSYCAGGQ-CRNTAGSFTCV---CPEGTRHEPELQLC 278
+C + C N GS+ C+ CP + +P C
Sbjct: 2515 LEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 2554
Score = 102 bits (244), Expect = 3e-21
Identities = 82/263 (31%), Positives = 110/263 (41%), Gaps = 43/263 (16%)
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDG 156
S+G C +G+ + C D DEC C + CHN G++ C C G T++ DG
Sbjct: 2122 SKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADG 2180
Query: 157 RTCLGL-KLGWGV-SCQA---CPAQ-GSELYAVLCPEGPSKDNGGA---DINECTAVPGA 207
RTC + + G +C A C GS V C G + + G DINEC
Sbjct: 2181 RTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSP 2239
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV-- 264
C H C N + C C+PGY C D++EC Q+ C Q C+NT G + C+
Sbjct: 2240 C-HQRCFNAIGSFHCGCEPGYQLKGRK-CMDVNEC--RQNVCRPDQHCKNTRGGYKCIDL 2295
Query: 265 CPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINT 324
CP G + E C DIDEC+ T + Y N C NT
Sbjct: 2296 CPNGMT-KAENGTCIDIDECKDGTH----QCRY--------------------NQICENT 2330
Query: 325 HGGFECECELGYVLDATAQRCLD 347
G + C C GY + C+D
Sbjct: 2331 RGSYRCVCPRGYRSQGVGRPCMD 2353
Score = 67.7 bits (158), Expect = 8e-11
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV-C-RNGR 134
C D+DEC C+ C N+ GS+QC+C GY+ T C D+DEC EQ V C N
Sbjct: 2468 CVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 2526
Query: 135 CHNTPGSFRC---ECLPGFTLSNDGRTCL 160
C N GS++C C P + CL
Sbjct: 2527 CFNMRGSYQCIDTPCPPNYQRDPVSGFCL 2555
Score = 49.6 bits (113), Expect = 2e-05
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 405 DGATCRDVDECALSAELC-AGGTCVNTDGSYRC--DCPPGLTLDSTG 448
DG TC+D+DECAL C AG C NT GSYRC C G S G
Sbjct: 2179 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDG 2225
Score = 46.4 bits (105), Expect = 2e-04
Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDSTG 448
G K + TC D+DEC C C NT GSYRC CP G G
Sbjct: 2299 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG 2348
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
TC D+DEC + + C C NT GSY+C CPPG L G
Sbjct: 2467 TCVDIDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNG 2505
Score = 42.3 bits (95), Expect = 0.003
Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D++EC + CA C NT GS++C CPPG L G
Sbjct: 2348 GRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDG 2389
Score = 41.5 bits (93), Expect = 0.006
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 24/132 (18%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
+PC + C N G + C C G + A + C D + R C A Q
Sbjct: 2153 NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHT----CHAG-------Q 2200
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDG 432
+C ++G GF + DG +C+D++EC S+ C N G
Sbjct: 2201 DCDNTIG---------SYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CHQRCFNAIG 2249
Query: 433 SYRCDCPPGLTL 444
S+ C C PG L
Sbjct: 2250 SFHCGCEPGYQL 2261
Score = 40.3 bits (90), Expect = 0.014
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D DECA + C+ +C N G+Y C CP GLT+ + G
Sbjct: 2140 GPFCADEDECA-AGNPCSH-SCHNAMGTYYCSCPKGLTIAADG 2180
Score = 36.7 bits (81), Expect = 0.17
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCPPGLTLD 445
+G TC+D+DEC C C N GSY+C CPP D
Sbjct: 2504 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 2548
Score = 36.3 bits (80), Expect = 0.22
Identities = 53/198 (26%), Positives = 76/198 (38%), Gaps = 33/198 (16%)
Query: 265 CPEGTRHEPELQLCRDIDECE-GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
CP G + C D DEC G +H + G + P +A+ + I+
Sbjct: 2130 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHN--AMGTYYCSCPKGLTIAADGRTCQDID 2187
Query: 324 THGGFECECELGYVLDAT--AQRCLDNRRGSCWRRVVDG-------QCEAAAPELLLRQE 374
C G D T + RC+ R GS +RR DG +C+ ++P Q
Sbjct: 2188 ECALGRHTCHAGQDCDNTIGSYRCVV-RCGSGFRRTSDGLSCQDINECQESSP---CHQR 2243
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGS 433
C ++G G+ +L G C DV+EC +C C NT G
Sbjct: 2244 CFNAIG-----------SFHCGCEPGY-QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGG 2289
Query: 434 YRCD--CPPGLTLDSTGT 449
Y+C CP G+T GT
Sbjct: 2290 YKCIDLCPNGMTKAENGT 2307
>Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP1-100N22 on chromosome 22q13.31-13.33. ).
Length = 988
Score = 164 bits (398), Expect = 7e-40
Identities = 117/374 (31%), Positives = 167/374 (44%), Gaps = 36/374 (9%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDN--PRVCRRGRCRNTAGSYTCLCE 66
+ IC+N ++C+CKPGY+ EG C D+DEC ++ C C N G+Y C C
Sbjct: 47 DAICQNTPKSYKCLCKPGYKG--EGKQCEDIDECENDYYNGGCVH-ECINIPGNYRCTCF 103
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF G+ C DVDEC ++ CVN+ GS++C C +G+ + + C+
Sbjct: 104 DGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIH--RSN 161
Query: 126 EQRVCRNGR------CHNTP-GSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQACPAQG 177
E C N C TP G C+C PGF L+ + + C L G G +C
Sbjct: 162 EGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTD 221
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LC 236
+ + +G I C G C +C++ G RC C G+ DG C
Sbjct: 222 TGPTCGCHQKYALHSDGRTCIETCAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTC 280
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI--- 293
+DI+EC ++ C CRNT GSF C C +G + + + C+DIDEC E +I
Sbjct: 281 KDINECLVNNGGC-DHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICIN 339
Query: 294 -----ESDYERGDI--PPTFPTRTELAS----PCDNGRCINTHGGFECECELGYVLDATA 342
+ RG I T + S CD G C+NT G +EC C G L
Sbjct: 340 SPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNG 398
Query: 343 QRCLDNRRGSCWRR 356
+ C++ G C R
Sbjct: 399 KDCVET--GKCLSR 410
Score = 150 bits (364), Expect = 9e-36
Identities = 133/435 (30%), Positives = 173/435 (39%), Gaps = 77/435 (17%)
Query: 29 SGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVDECAADS 87
SG G++ DVDEC + C C+NT SY CLC+PG+ C D+DEC D
Sbjct: 26 SGLPGSV--DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGK-QCEDIDECENDY 82
Query: 88 MCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCE 145
G C+N G+++C C G+ C+DVDEC++ C N GS+ C+
Sbjct: 83 YNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQ 142
Query: 146 CLPGFTLS----------NDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG 195
C GF LS N+G C+ G C+ P G A C G
Sbjct: 143 CHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGG---VACDCRPGFDLAQNQ 199
Query: 196 ADIN-ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQ 253
D C G C H SCE+ + G C C Y +DG C I+ C ++ C
Sbjct: 200 KDCTLTCNYGNGGCQH-SCEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGC-DRT 255
Query: 254 CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELA 313
C++TA C CP G +P+ G+T E G
Sbjct: 256 CKDTATGVRCSCPVGFTLQPD-----------GKTCKDINECLVNNGG------------ 292
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
CD+ C NT G FEC C GY L + C D S + R D C +
Sbjct: 293 --CDHF-CRNTVGSFECGCRKGYKLLTDERTCQDIDECS-FERTCDHICINSPGSF---- 344
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGS 433
+C C +G+ C DVDEC++S C G CVNT GS
Sbjct: 345 QCLCH--------------------RGYILYGTTHCGDVDECSMSNGSCDQG-CVNTKGS 383
Query: 434 YRCDCPPGLTLDSTG 448
Y C CPPG L G
Sbjct: 384 YECVCPPGRRLHWNG 398
Score = 120 bits (290), Expect = 8e-27
Identities = 89/292 (30%), Positives = 116/292 (39%), Gaps = 19/292 (6%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C NI G + C C G+ +G C DVDEC+DN C++ C N GSY
Sbjct: 84 NGG-CVHE-CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYE 140
Query: 63 CLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVN-----SEGSFQCVCEAGYRPTATRG 116
C C GF + + C + M K C + +G C C G+ +
Sbjct: 141 CQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQK 200
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
C C C +T C C + L +DGRTC+ C
Sbjct: 201 DCTLT--CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKD 258
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ CP G + G DINEC G C H C N + C C GY D
Sbjct: 259 TATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH-FCRNTVGSFECGCRKGYKLLTD 317
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C+DIDEC ++ C N+ GSF C+C G C D+DEC
Sbjct: 318 ERTCQDIDECSFERT--CDHICINSPGSFQCLCHRGYILYGTTH-CGDVDEC 366
Score = 101 bits (241), Expect = 7e-21
Identities = 70/204 (34%), Positives = 94/204 (46%), Gaps = 16/204 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C++ D G C C Y S+G C ++ C N C R C++TA
Sbjct: 210 NGG-CQHS-CEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGCDR-TCKDTATGVR 264
Query: 63 CLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C GF G C D++EC ++ C N+ GSF+C C GY+ C D+
Sbjct: 265 CSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDI 324
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLG----LKLGWGVSCQAC-PAQ 176
DEC +R C + C N+PGSF+C C G+ L G T G + G Q C +
Sbjct: 325 DECSFERTC-DHICINSPGSFQCLCHRGYILY--GTTHCGDVDECSMSNGSCDQGCVNTK 381
Query: 177 GSELYAVLCPEGPSKDNGGADINE 200
GS Y +CP G G D E
Sbjct: 382 GS--YECVCPPGRRLHWNGKDCVE 403
Score = 99.1 bits (236), Expect = 3e-20
Identities = 48/125 (38%), Positives = 70/125 (56%), Gaps = 5/125 (4%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGS 60
+ N G C + C+N G FEC C+ GY+ ++ C+D+DEC R C C N+ GS
Sbjct: 287 LVNNGGCDH-FCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFE-RTCDH-ICINSPGS 343
Query: 61 YTCLCEPGFAPTAAGYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
+ CLC G+ +C DVDEC+ ++ C G CVN++GS++CVC G R CV
Sbjct: 344 FQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCV 402
Query: 120 DVDEC 124
+ +C
Sbjct: 403 ETGKC 407
Score = 38.7 bits (86), Expect = 0.042
Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 4/65 (6%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR--CRNTA 58
M+NG C G C N G +EC+C PG G C + +C + R + C
Sbjct: 368 MSNGS-CDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAG 425
Query: 59 GSYTC 63
G +C
Sbjct: 426 GVESC 430
>Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP3-526I14 on chromosome 22. ).
Length = 988
Score = 164 bits (398), Expect = 7e-40
Identities = 117/374 (31%), Positives = 167/374 (44%), Gaps = 36/374 (9%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDN--PRVCRRGRCRNTAGSYTCLCE 66
+ IC+N ++C+CKPGY+ EG C D+DEC ++ C C N G+Y C C
Sbjct: 47 DAICQNTPKSYKCLCKPGYKG--EGKQCEDIDECENDYYNGGCVH-ECINIPGNYRCTCF 103
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF G+ C DVDEC ++ CVN+ GS++C C +G+ + + C+
Sbjct: 104 DGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIH--RSN 161
Query: 126 EQRVCRNGR------CHNTP-GSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQACPAQG 177
E C N C TP G C+C PGF L+ + + C L G G +C
Sbjct: 162 EGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTD 221
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LC 236
+ + +G I C G C +C++ G RC C G+ DG C
Sbjct: 222 TGPTCGCHQKYALHSDGRTCIETCAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTC 280
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI--- 293
+DI+EC ++ C CRNT GSF C C +G + + + C+DIDEC E +I
Sbjct: 281 KDINECLVNNGGC-DHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICIN 339
Query: 294 -----ESDYERGDI--PPTFPTRTELAS----PCDNGRCINTHGGFECECELGYVLDATA 342
+ RG I T + S CD G C+NT G +EC C G L
Sbjct: 340 SPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNG 398
Query: 343 QRCLDNRRGSCWRR 356
+ C++ G C R
Sbjct: 399 KDCVET--GKCLSR 410
Score = 150 bits (364), Expect = 9e-36
Identities = 133/435 (30%), Positives = 173/435 (39%), Gaps = 77/435 (17%)
Query: 29 SGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVDECAADS 87
SG G++ DVDEC + C C+NT SY CLC+PG+ C D+DEC D
Sbjct: 26 SGLPGSV--DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGK-QCEDIDECENDY 82
Query: 88 MCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCE 145
G C+N G+++C C G+ C+DVDEC++ C N GS+ C+
Sbjct: 83 YNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQ 142
Query: 146 CLPGFTLS----------NDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG 195
C GF LS N+G C+ G C+ P G A C G
Sbjct: 143 CHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGG---VACDCRPGFDLAQNQ 199
Query: 196 ADIN-ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQ 253
D C G C H SCE+ + G C C Y +DG C I+ C ++ C
Sbjct: 200 KDCTLTCNYGNGGCQH-SCEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGC-DRT 255
Query: 254 CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELA 313
C++TA C CP G +P+ G+T E G
Sbjct: 256 CKDTATGVRCSCPVGFTLQPD-----------GKTCKDINECLVNNGG------------ 292
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
CD+ C NT G FEC C GY L + C D S + R D C +
Sbjct: 293 --CDHF-CRNTVGSFECGCRKGYKLLTDERTCQDIDECS-FERTCDHICINSPGSF---- 344
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGS 433
+C C +G+ C DVDEC++S C G CVNT GS
Sbjct: 345 QCLCH--------------------RGYILYGTTHCGDVDECSMSNGSCDQG-CVNTKGS 383
Query: 434 YRCDCPPGLTLDSTG 448
Y C CPPG L G
Sbjct: 384 YECVCPPGRRLHWNG 398
Score = 120 bits (290), Expect = 8e-27
Identities = 89/292 (30%), Positives = 116/292 (39%), Gaps = 19/292 (6%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C NI G + C C G+ +G C DVDEC+DN C++ C N GSY
Sbjct: 84 NGG-CVHE-CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYE 140
Query: 63 CLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVN-----SEGSFQCVCEAGYRPTATRG 116
C C GF + + C + M K C + +G C C G+ +
Sbjct: 141 CQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQK 200
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
C C C +T C C + L +DGRTC+ C
Sbjct: 201 DCTLT--CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKD 258
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ CP G + G DINEC G C H C N + C C GY D
Sbjct: 259 TATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH-FCRNTVGSFECGCRKGYKLLTD 317
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C+DIDEC ++ C N+ GSF C+C G C D+DEC
Sbjct: 318 ERTCQDIDECSFERT--CDHICINSPGSFQCLCHRGYILYGTTH-CGDVDEC 366
Score = 101 bits (241), Expect = 7e-21
Identities = 70/204 (34%), Positives = 94/204 (46%), Gaps = 16/204 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C++ D G C C Y S+G C ++ C N C R C++TA
Sbjct: 210 NGG-CQHS-CEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGCDR-TCKDTATGVR 264
Query: 63 CLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C GF G C D++EC ++ C N+ GSF+C C GY+ C D+
Sbjct: 265 CSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDI 324
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLG----LKLGWGVSCQAC-PAQ 176
DEC +R C + C N+PGSF+C C G+ L G T G + G Q C +
Sbjct: 325 DECSFERTC-DHICINSPGSFQCLCHRGYILY--GTTHCGDVDECSMSNGSCDQGCVNTK 381
Query: 177 GSELYAVLCPEGPSKDNGGADINE 200
GS Y +CP G G D E
Sbjct: 382 GS--YECVCPPGRRLHWNGKDCVE 403
Score = 99.1 bits (236), Expect = 3e-20
Identities = 48/125 (38%), Positives = 70/125 (56%), Gaps = 5/125 (4%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGS 60
+ N G C + C+N G FEC C+ GY+ ++ C+D+DEC R C C N+ GS
Sbjct: 287 LVNNGGCDH-FCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFE-RTCDH-ICINSPGS 343
Query: 61 YTCLCEPGFAPTAAGYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
+ CLC G+ +C DVDEC+ ++ C G CVN++GS++CVC G R CV
Sbjct: 344 FQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCV 402
Query: 120 DVDEC 124
+ +C
Sbjct: 403 ETGKC 407
Score = 38.7 bits (86), Expect = 0.042
Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 4/65 (6%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR--CRNTA 58
M+NG C G C N G +EC+C PG G C + +C + R + C
Sbjct: 368 MSNGS-CDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAG 425
Query: 59 GSYTC 63
G +C
Sbjct: 426 GVESC 430
>Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 163 bits (396), Expect = 1e-39
Identities = 113/313 (36%), Positives = 143/313 (45%), Gaps = 33/313 (10%)
Query: 1 MTNGGMCTNG-ICKNIDGGFEC----ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-C 54
+T C G C N G F C C GYE + + C+D+DEC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFIC 279
Query: 55 RNTAGSYTCL----CEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCV---- 104
+NT GS+ C C+ GF A G C D++EC + S C G C+N+EGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 105 -CEAGYRPTATRGACVDVDECEEQ-RVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLG 161
C GY CVDVDEC C G RC N+PGSFRCEC G+ R C+
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 162 LKLGWGVSCQACPAQGSEL---YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ + C + Y C G G DINEC++ P C C N
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECAN 456
Query: 216 LEPGYRCICDPGYH-PDADGL-CRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPE-GTRH 271
+ Y+C C GY D DG+ C DIDEC + + +C N GSF C CP G R
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRL 516
Query: 272 EPELQLCRDIDEC 284
P + C+DIDEC
Sbjct: 517 APNGRNCQDIDEC 529
Score = 142 bits (344), Expect = 2e-33
Identities = 121/377 (32%), Positives = 159/377 (42%), Gaps = 67/377 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
GG C C++ C C GY+ S+G C DV+EC CR G C NT GS+
Sbjct: 183 GGPCKQQ-CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 63 C----LCEPGFAPTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQC----VCEAGYRPT 112
C C G+ T C D+DEC + + C N+ GSF+C C++G+
Sbjct: 242 CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 113 ATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRCE-----CLPGFTLSNDGRTCLGL--- 162
A G C+D++EC C G C NT GS+ C+ C G+ L+ +G C+ +
Sbjct: 302 AL-GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 360
Query: 163 -----KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPG-ACPHGSC 213
G G C P GS + C G D D+NEC PG C H C
Sbjct: 361 APPAEPCGKGHRCVNSP--GS--FRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 214 ENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR-H 271
EN Y C C G+ DG C DI+EC S C+ +C N GS+ C C G +
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLS 472
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ + C DIDEC PT + S RCIN G F+C
Sbjct: 473 DVDGVTCEDIDEC--------------------ALPTGGHICS----YRCINIPGSFQCS 508
Query: 332 C-ELGYVLDATAQRCLD 347
C GY L + C D
Sbjct: 509 CPSSGYRLAPNGRNCQD 525
Score = 114 bits (274), Expect = 7e-25
Identities = 79/245 (32%), Positives = 113/245 (46%), Gaps = 29/245 (11%)
Query: 12 CKNIDGGFECI-----CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLC 65
C N +G + C C GY EG C DVDEC C +G RC N+ GS+ C C
Sbjct: 325 CINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 384
Query: 66 EPGFA-PTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+ G+ + C DV+EC +C G +C N+ GS+ C C G+R + +C D++
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLC-GHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN 443
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN-DGRTC-----LGLKLGWGVSCQAC-PA 175
EC + C N GS++C C G+ LS+ DG TC L G + C
Sbjct: 444 ECSSSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINI 501
Query: 176 QGSELYAVLCPEGPSK--DNGG--ADINEC-TAVPGACPHGSCENLEPGYRCI---CDPG 227
GS + CP + NG DI+EC T + + +C N++ G+RC+ C
Sbjct: 502 PGS--FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPEN 559
Query: 228 YHPDA 232
Y A
Sbjct: 560 YRRSA 564
Score = 107 bits (256), Expect = 1e-22
Identities = 101/362 (27%), Positives = 145/362 (40%), Gaps = 73/362 (20%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSE 179
D C C+ +C +T C C G+ L +DG +C + + SC+ + +
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 180 LYAVLCPEGPS--------KDNGGADINEC-TAVPGACPHGSCENLEPGYRCI----CDP 226
+ + C S +DN DI+EC + + P C+N +RC C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 227 GYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCV-----CPEGTRHEPELQLCRD 280
G+ DA G C DI+EC + C G C NT GS+TC C G E C D
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD 356
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLD 339
+DEC PP A PC G RC+N+ G F CEC+ GY D
Sbjct: 357 VDECA-----------------PP--------AEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 340 ATAQRCLDNRRGSCWR---RVVDGQCE----------AAAPELLLRQECC-----CSVGL 381
++ C+D C R R+ +CE + L + C CS
Sbjct: 392 GISRMCVDVNE--CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP 449
Query: 382 AWGSXXXXXXXXXXXXXKGF--AKLDGATCRDVDECAL--SAELCAGGTCVNTDGSYRCD 437
+G+ + +DG TC D+DECAL +C+ C+N GS++C
Sbjct: 450 CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCS 508
Query: 438 CP 439
CP
Sbjct: 509 CP 510
Score = 70.9 bits (166), Expect = 8e-12
Identities = 87/303 (28%), Positives = 109/303 (35%), Gaps = 67/303 (22%)
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHG-SCENLEPGY 220
G G Q C G E+ C G + G D+NEC +C G SC N +
Sbjct: 182 GGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 221 RC----ICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTC----VCPEGTRH 271
RC C GY D C+DIDEC+ C C+NT GSF C C G
Sbjct: 241 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR-CINTHGGFEC 330
+ L C DI+EC +++PC G CINT G + C
Sbjct: 301 DA-LGNCIDINEC-------------------------LSISAPCPIGHTCINTEGSYTC 334
Query: 331 E-----CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
+ C GY L+ RC+D VD +C A C S G
Sbjct: 335 QKNVPNCGRGYHLNEEGTRCVD----------VD-ECAPPAEPCGKGHRCVNSPG----- 378
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G +++ C DV+EC G C NT GSY C C G L
Sbjct: 379 -SFRCECKTGYYFDGISRM----CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLS 433
Query: 446 STG 448
G
Sbjct: 434 VDG 436
Score = 50.4 bits (115), Expect = 1e-05
Identities = 58/216 (26%), Positives = 80/216 (37%), Gaps = 23/216 (10%)
Query: 249 CAGG-----QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP 303
C GG QCR+T C C G + + C D++EC T +H +
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECI--TGSHSCRLGESCINTV 237
Query: 304 PTFPTRTELASPCDNGRCINTHGGFEC--ECELGY---VLDATAQRCLDNRRGSCWRRVV 358
+F R + S C G + + ECE G + D Q L + R +
Sbjct: 238 GSF--RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 359 DGQCEAAAPELLLRQECC-----CSVGLAWGSXXXXXXXXXXXXXKG---FAKLDGATCR 410
G + A + EC C +G + G +G C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 411 DVDECALSAELCAGG-TCVNTDGSYRCDCPPGLTLD 445
DVDECA AE C G CVN+ GS+RC+C G D
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 46.4 bits (105), Expect = 2e-04
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 6/78 (7%)
Query: 2 TNGGMCTNGICKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAG 59
T G +C+ C NI G F+C C GY G C+D+DEC C C N G
Sbjct: 489 TGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 60 SYTCL---CEPGFAPTAA 74
+ CL C + +AA
Sbjct: 548 GFRCLAFECPENYRRSAA 565
Score = 40.3 bits (90), Expect = 0.014
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 6/56 (10%)
Query: 400 GFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC-----DCPPGLTLDSTGT 449
GF + C D++EC ++SA G TC+NT+GSY C +C G L+ GT
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Score = 36.7 bits (81), Expect = 0.17
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCP 439
+G C+D+DEC C+ TC N G +RC +CP
Sbjct: 519 NGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 557
>Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 163 bits (396), Expect = 1e-39
Identities = 113/313 (36%), Positives = 143/313 (45%), Gaps = 33/313 (10%)
Query: 1 MTNGGMCTNG-ICKNIDGGFEC----ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-C 54
+T C G C N G F C C GYE + + C+D+DEC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFIC 279
Query: 55 RNTAGSYTCL----CEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCV---- 104
+NT GS+ C C+ GF A G C D++EC + S C G C+N+EGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 105 -CEAGYRPTATRGACVDVDECEEQ-RVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLG 161
C GY CVDVDEC C G RC N+PGSFRCEC G+ R C+
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 162 LKLGWGVSCQACPAQGSEL---YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ + C + Y C G G DINEC++ P C C N
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECAN 456
Query: 216 LEPGYRCICDPGYH-PDADGL-CRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPE-GTRH 271
+ Y+C C GY D DG+ C DIDEC + + +C N GSF C CP G R
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRL 516
Query: 272 EPELQLCRDIDEC 284
P + C+DIDEC
Sbjct: 517 APNGRNCQDIDEC 529
Score = 142 bits (344), Expect = 2e-33
Identities = 121/377 (32%), Positives = 159/377 (42%), Gaps = 67/377 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
GG C C++ C C GY+ S+G C DV+EC CR G C NT GS+
Sbjct: 183 GGPCKQQ-CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 63 C----LCEPGFAPTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQC----VCEAGYRPT 112
C C G+ T C D+DEC + + C N+ GSF+C C++G+
Sbjct: 242 CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 113 ATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRCE-----CLPGFTLSNDGRTCLGL--- 162
A G C+D++EC C G C NT GS+ C+ C G+ L+ +G C+ +
Sbjct: 302 AL-GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 360
Query: 163 -----KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPG-ACPHGSC 213
G G C P GS + C G D D+NEC PG C H C
Sbjct: 361 APPAEPCGKGHRCVNSP--GS--FRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 214 ENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR-H 271
EN Y C C G+ DG C DI+EC S C+ +C N GS+ C C G +
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLS 472
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ + C DIDEC PT + S RCIN G F+C
Sbjct: 473 DVDGVTCEDIDEC--------------------ALPTGGHICS----YRCINIPGSFQCS 508
Query: 332 C-ELGYVLDATAQRCLD 347
C GY L + C D
Sbjct: 509 CPSSGYRLAPNGRNCQD 525
Score = 114 bits (274), Expect = 7e-25
Identities = 79/245 (32%), Positives = 113/245 (46%), Gaps = 29/245 (11%)
Query: 12 CKNIDGGFECI-----CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLC 65
C N +G + C C GY EG C DVDEC C +G RC N+ GS+ C C
Sbjct: 325 CINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 384
Query: 66 EPGFA-PTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+ G+ + C DV+EC +C G +C N+ GS+ C C G+R + +C D++
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLC-GHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN 443
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN-DGRTC-----LGLKLGWGVSCQAC-PA 175
EC + C N GS++C C G+ LS+ DG TC L G + C
Sbjct: 444 ECSSSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINI 501
Query: 176 QGSELYAVLCPEGPSK--DNGG--ADINEC-TAVPGACPHGSCENLEPGYRCI---CDPG 227
GS + CP + NG DI+EC T + + +C N++ G+RC+ C
Sbjct: 502 PGS--FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPEN 559
Query: 228 YHPDA 232
Y A
Sbjct: 560 YRRSA 564
Score = 107 bits (256), Expect = 1e-22
Identities = 101/362 (27%), Positives = 145/362 (40%), Gaps = 73/362 (20%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSE 179
D C C+ +C +T C C G+ L +DG +C + + SC+ + +
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 180 LYAVLCPEGPS--------KDNGGADINEC-TAVPGACPHGSCENLEPGYRCI----CDP 226
+ + C S +DN DI+EC + + P C+N +RC C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 227 GYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCV-----CPEGTRHEPELQLCRD 280
G+ DA G C DI+EC + C G C NT GS+TC C G E C D
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD 356
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLD 339
+DEC PP A PC G RC+N+ G F CEC+ GY D
Sbjct: 357 VDECA-----------------PP--------AEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 340 ATAQRCLDNRRGSCWR---RVVDGQCE----------AAAPELLLRQECC-----CSVGL 381
++ C+D C R R+ +CE + L + C CS
Sbjct: 392 GISRMCVDVNE--CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP 449
Query: 382 AWGSXXXXXXXXXXXXXKGF--AKLDGATCRDVDECAL--SAELCAGGTCVNTDGSYRCD 437
+G+ + +DG TC D+DECAL +C+ C+N GS++C
Sbjct: 450 CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCS 508
Query: 438 CP 439
CP
Sbjct: 509 CP 510
Score = 70.9 bits (166), Expect = 8e-12
Identities = 87/303 (28%), Positives = 109/303 (35%), Gaps = 67/303 (22%)
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHG-SCENLEPGY 220
G G Q C G E+ C G + G D+NEC +C G SC N +
Sbjct: 182 GGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 221 RC----ICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTC----VCPEGTRH 271
RC C GY D C+DIDEC+ C C+NT GSF C C G
Sbjct: 241 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR-CINTHGGFEC 330
+ L C DI+EC +++PC G CINT G + C
Sbjct: 301 DA-LGNCIDINEC-------------------------LSISAPCPIGHTCINTEGSYTC 334
Query: 331 E-----CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
+ C GY L+ RC+D VD +C A C S G
Sbjct: 335 QKNVPNCGRGYHLNEEGTRCVD----------VD-ECAPPAEPCGKGHRCVNSPG----- 378
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G +++ C DV+EC G C NT GSY C C G L
Sbjct: 379 -SFRCECKTGYYFDGISRM----CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLS 433
Query: 446 STG 448
G
Sbjct: 434 VDG 436
Score = 50.4 bits (115), Expect = 1e-05
Identities = 58/216 (26%), Positives = 80/216 (37%), Gaps = 23/216 (10%)
Query: 249 CAGG-----QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP 303
C GG QCR+T C C G + + C D++EC T +H +
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECI--TGSHSCRLGESCINTV 237
Query: 304 PTFPTRTELASPCDNGRCINTHGGFEC--ECELGY---VLDATAQRCLDNRRGSCWRRVV 358
+F R + S C G + + ECE G + D Q L + R +
Sbjct: 238 GSF--RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 359 DGQCEAAAPELLLRQECC-----CSVGLAWGSXXXXXXXXXXXXXKG---FAKLDGATCR 410
G + A + EC C +G + G +G C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 411 DVDECALSAELCAGG-TCVNTDGSYRCDCPPGLTLD 445
DVDECA AE C G CVN+ GS+RC+C G D
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 46.4 bits (105), Expect = 2e-04
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 6/78 (7%)
Query: 2 TNGGMCTNGICKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAG 59
T G +C+ C NI G F+C C GY G C+D+DEC C C N G
Sbjct: 489 TGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 60 SYTCL---CEPGFAPTAA 74
+ CL C + +AA
Sbjct: 548 GFRCLAFECPENYRRSAA 565
Score = 40.3 bits (90), Expect = 0.014
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 6/56 (10%)
Query: 400 GFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC-----DCPPGLTLDSTGT 449
GF + C D++EC ++SA G TC+NT+GSY C +C G L+ GT
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Score = 36.7 bits (81), Expect = 0.17
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCP 439
+G C+D+DEC C+ TC N G +RC +CP
Sbjct: 519 NGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 557
>X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein.
Length = 683
Score = 163 bits (396), Expect = 1e-39
Identities = 113/313 (36%), Positives = 143/313 (45%), Gaps = 33/313 (10%)
Query: 1 MTNGGMCTNG-ICKNIDGGFEC----ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-C 54
+T C G C N G F C C GYE + + C+D+DEC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFIC 279
Query: 55 RNTAGSYTCL----CEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCV---- 104
+NT GS+ C C+ GF A G C D++EC + S C G C+N+EGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 105 -CEAGYRPTATRGACVDVDECEEQ-RVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLG 161
C GY CVDVDEC C G RC N+PGSFRCEC G+ R C+
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 162 LKLGWGVSCQACPAQGSEL---YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ + C + Y C G G DINEC++ P C C N
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECAN 456
Query: 216 LEPGYRCICDPGYH-PDADGL-CRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPE-GTRH 271
+ Y+C C GY D DG+ C DIDEC + + +C N GSF C CP G R
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRL 516
Query: 272 EPELQLCRDIDEC 284
P + C+DIDEC
Sbjct: 517 APNGRNCQDIDEC 529
Score = 142 bits (344), Expect = 2e-33
Identities = 121/377 (32%), Positives = 159/377 (42%), Gaps = 67/377 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
GG C C++ C C GY+ S+G C DV+EC CR G C NT GS+
Sbjct: 183 GGPCKQQ-CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 63 C----LCEPGFAPTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQC----VCEAGYRPT 112
C C G+ T C D+DEC + + C N+ GSF+C C++G+
Sbjct: 242 CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 113 ATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRCE-----CLPGFTLSNDGRTCLGL--- 162
A G C+D++EC C G C NT GS+ C+ C G+ L+ +G C+ +
Sbjct: 302 AL-GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 360
Query: 163 -----KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPG-ACPHGSC 213
G G C P GS + C G D D+NEC PG C H C
Sbjct: 361 APPAEPCGKGHRCVNSP--GS--FRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 214 ENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR-H 271
EN Y C C G+ DG C DI+EC S C+ +C N GS+ C C G +
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLS 472
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ + C DIDEC PT + S RCIN G F+C
Sbjct: 473 DVDGVTCEDIDEC--------------------ALPTGGHICS----YRCINIPGSFQCS 508
Query: 332 C-ELGYVLDATAQRCLD 347
C GY L + C D
Sbjct: 509 CPSSGYRLAPNGRNCQD 525
Score = 109 bits (263), Expect = 1e-23
Identities = 75/220 (34%), Positives = 100/220 (45%), Gaps = 35/220 (15%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNP-RVCRRGRCRNTAGSYTCLCEPGFA 70
C N G F C CK GY +C DV+EC+ P R+C +C NT GSY C C GF
Sbjct: 373 CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFR 431
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDECEEQ- 127
+ G C D++EC++ S C C N GS+QC C GY+ + G C D+DEC
Sbjct: 432 LSVDGRSCEDINECSS-SPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 489
Query: 128 --RVCRNGRCHNTPGSFRCEC-LPGFTLSNDGRTCLGL-----------------KLGWG 167
+C + RC N PGSF+C C G+ L+ +GR C + +
Sbjct: 490 GGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGA 548
Query: 168 VSCQA--CPAQGSELYAVLCPEGPSKDNGGADINECTAVP 205
C A CP A C P +N EC+ +P
Sbjct: 549 FRCLAFECPENYRRSAATRCERLPCHEN-----RECSKLP 583
Score = 107 bits (256), Expect = 1e-22
Identities = 101/362 (27%), Positives = 145/362 (40%), Gaps = 73/362 (20%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSE 179
D C C+ +C +T C C G+ L +DG +C + + SC+ + +
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 180 LYAVLCPEGPS--------KDNGGADINEC-TAVPGACPHGSCENLEPGYRCI----CDP 226
+ + C S +DN DI+EC + + P C+N +RC C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 227 GYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCV-----CPEGTRHEPELQLCRD 280
G+ DA G C DI+EC + C G C NT GS+TC C G E C D
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD 356
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLD 339
+DEC PP A PC G RC+N+ G F CEC+ GY D
Sbjct: 357 VDECA-----------------PP--------AEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 340 ATAQRCLDNRRGSCWR---RVVDGQCE----------AAAPELLLRQECC-----CSVGL 381
++ C+D C R R+ +CE + L + C CS
Sbjct: 392 GISRMCVDVNE--CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP 449
Query: 382 AWGSXXXXXXXXXXXXXKGF--AKLDGATCRDVDECAL--SAELCAGGTCVNTDGSYRCD 437
+G+ + +DG TC D+DECAL +C+ C+N GS++C
Sbjct: 450 CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCS 508
Query: 438 CP 439
CP
Sbjct: 509 CP 510
Score = 70.9 bits (166), Expect = 8e-12
Identities = 87/303 (28%), Positives = 109/303 (35%), Gaps = 67/303 (22%)
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHG-SCENLEPGY 220
G G Q C G E+ C G + G D+NEC +C G SC N +
Sbjct: 182 GGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 221 RC----ICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTC----VCPEGTRH 271
RC C GY D C+DIDEC+ C C+NT GSF C C G
Sbjct: 241 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR-CINTHGGFEC 330
+ L C DI+EC +++PC G CINT G + C
Sbjct: 301 DA-LGNCIDINEC-------------------------LSISAPCPIGHTCINTEGSYTC 334
Query: 331 E-----CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
+ C GY L+ RC+D VD +C A C S G
Sbjct: 335 QKNVPNCGRGYHLNEEGTRCVD----------VD-ECAPPAEPCGKGHRCVNSPG----- 378
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G +++ C DV+EC G C NT GSY C C G L
Sbjct: 379 -SFRCECKTGYYFDGISRM----CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLS 433
Query: 446 STG 448
G
Sbjct: 434 VDG 436
Score = 50.4 bits (115), Expect = 1e-05
Identities = 58/216 (26%), Positives = 80/216 (37%), Gaps = 23/216 (10%)
Query: 249 CAGG-----QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP 303
C GG QCR+T C C G + + C D++EC T +H +
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECI--TGSHSCRLGESCINTV 237
Query: 304 PTFPTRTELASPCDNGRCINTHGGFEC--ECELGY---VLDATAQRCLDNRRGSCWRRVV 358
+F R + S C G + + ECE G + D Q L + R +
Sbjct: 238 GSF--RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 359 DGQCEAAAPELLLRQECC-----CSVGLAWGSXXXXXXXXXXXXXKG---FAKLDGATCR 410
G + A + EC C +G + G +G C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 411 DVDECALSAELCAGG-TCVNTDGSYRCDCPPGLTLD 445
DVDECA AE C G CVN+ GS+RC+C G D
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 48.8 bits (111), Expect = 4e-05
Identities = 28/81 (34%), Positives = 37/81 (45%), Gaps = 6/81 (7%)
Query: 2 TNGGMCTNGICKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAG 59
T G +C+ C NI G F+C C GY G C+D+DEC C C N G
Sbjct: 489 TGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 60 SYTCL---CEPGFAPTAAGYC 77
++ CL C + +AA C
Sbjct: 548 AFRCLAFECPENYRRSAATRC 568
Score = 40.3 bits (90), Expect = 0.014
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 6/56 (10%)
Query: 400 GFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC-----DCPPGLTLDSTGT 449
GF + C D++EC ++SA G TC+NT+GSY C +C G L+ GT
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Score = 37.1 bits (82), Expect = 0.13
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 4/39 (10%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCP 439
+G C+D+DEC C+ TC N G++RC +CP
Sbjct: 519 NGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECP 557
>X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein.
Length = 601
Score = 163 bits (396), Expect = 1e-39
Identities = 113/313 (36%), Positives = 143/313 (45%), Gaps = 33/313 (10%)
Query: 1 MTNGGMCTNG-ICKNIDGGFEC----ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-C 54
+T C G C N G F C C GYE + + C+D+DEC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFIC 279
Query: 55 RNTAGSYTCL----CEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCV---- 104
+NT GS+ C C+ GF A G C D++EC + S C G C+N+EGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 105 -CEAGYRPTATRGACVDVDECEEQ-RVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLG 161
C GY CVDVDEC C G RC N+PGSFRCEC G+ R C+
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 162 LKLGWGVSCQACPAQGSEL---YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ + C + Y C G G DINEC++ P C C N
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECAN 456
Query: 216 LEPGYRCICDPGYH-PDADGL-CRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPE-GTRH 271
+ Y+C C GY D DG+ C DIDEC + + +C N GSF C CP G R
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRL 516
Query: 272 EPELQLCRDIDEC 284
P + C+DIDEC
Sbjct: 517 APNGRNCQDIDEC 529
Score = 142 bits (344), Expect = 2e-33
Identities = 121/377 (32%), Positives = 159/377 (42%), Gaps = 67/377 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
GG C C++ C C GY+ S+G C DV+EC CR G C NT GS+
Sbjct: 183 GGPCKQQ-CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 63 C----LCEPGFAPTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQC----VCEAGYRPT 112
C C G+ T C D+DEC + + C N+ GSF+C C++G+
Sbjct: 242 CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 113 ATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRCE-----CLPGFTLSNDGRTCLGL--- 162
A G C+D++EC C G C NT GS+ C+ C G+ L+ +G C+ +
Sbjct: 302 AL-GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 360
Query: 163 -----KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPG-ACPHGSC 213
G G C P GS + C G D D+NEC PG C H C
Sbjct: 361 APPAEPCGKGHRCVNSP--GS--FRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 214 ENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR-H 271
EN Y C C G+ DG C DI+EC S C+ +C N GS+ C C G +
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLS 472
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ + C DIDEC PT + S RCIN G F+C
Sbjct: 473 DVDGVTCEDIDEC--------------------ALPTGGHICS----YRCINIPGSFQCS 508
Query: 332 C-ELGYVLDATAQRCLD 347
C GY L + C D
Sbjct: 509 CPSSGYRLAPNGRNCQD 525
Score = 107 bits (256), Expect = 1e-22
Identities = 101/362 (27%), Positives = 145/362 (40%), Gaps = 73/362 (20%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSE 179
D C C+ +C +T C C G+ L +DG +C + + SC+ + +
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 180 LYAVLCPEGPS--------KDNGGADINEC-TAVPGACPHGSCENLEPGYRCI----CDP 226
+ + C S +DN DI+EC + + P C+N +RC C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 227 GYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCV-----CPEGTRHEPELQLCRD 280
G+ DA G C DI+EC + C G C NT GS+TC C G E C D
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD 356
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLD 339
+DEC PP A PC G RC+N+ G F CEC+ GY D
Sbjct: 357 VDECA-----------------PP--------AEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 340 ATAQRCLDNRRGSCWR---RVVDGQCE----------AAAPELLLRQECC-----CSVGL 381
++ C+D C R R+ +CE + L + C CS
Sbjct: 392 GISRMCVDVNE--CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP 449
Query: 382 AWGSXXXXXXXXXXXXXKGF--AKLDGATCRDVDECAL--SAELCAGGTCVNTDGSYRCD 437
+G+ + +DG TC D+DECAL +C+ C+N GS++C
Sbjct: 450 CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCS 508
Query: 438 CP 439
CP
Sbjct: 509 CP 510
Score = 97.5 bits (232), Expect = 9e-20
Identities = 54/149 (36%), Positives = 73/149 (48%), Gaps = 13/149 (8%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C + C+N G + C C G+ +G C D++EC +P C + C N GSY C
Sbjct: 408 GRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECANVYGSYQC 463
Query: 64 LCEPGF--APTAAGYCADVDECAADS---MCKGGRCVNSEGSFQCVC-EAGYRPTATRGA 117
C G+ + C D+DECA + +C RC+N GSFQC C +GYR
Sbjct: 464 YCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPNGRN 522
Query: 118 CVDVDECEE--QRVCRNGRCHNTPGSFRC 144
C D+DEC N C N G+FRC
Sbjct: 523 CQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 70.9 bits (166), Expect = 8e-12
Identities = 87/303 (28%), Positives = 109/303 (35%), Gaps = 67/303 (22%)
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHG-SCENLEPGY 220
G G Q C G E+ C G + G D+NEC +C G SC N +
Sbjct: 182 GGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 221 RC----ICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTC----VCPEGTRH 271
RC C GY D C+DIDEC+ C C+NT GSF C C G
Sbjct: 241 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR-CINTHGGFEC 330
+ L C DI+EC +++PC G CINT G + C
Sbjct: 301 DA-LGNCIDINEC-------------------------LSISAPCPIGHTCINTEGSYTC 334
Query: 331 E-----CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
+ C GY L+ RC+D VD +C A C S G
Sbjct: 335 QKNVPNCGRGYHLNEEGTRCVD----------VD-ECAPPAEPCGKGHRCVNSPG----- 378
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G +++ C DV+EC G C NT GSY C C G L
Sbjct: 379 -SFRCECKTGYYFDGISRM----CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLS 433
Query: 446 STG 448
G
Sbjct: 434 VDG 436
Score = 50.4 bits (115), Expect = 1e-05
Identities = 58/216 (26%), Positives = 80/216 (37%), Gaps = 23/216 (10%)
Query: 249 CAGG-----QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP 303
C GG QCR+T C C G + + C D++EC T +H +
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECI--TGSHSCRLGESCINTV 237
Query: 304 PTFPTRTELASPCDNGRCINTHGGFEC--ECELGY---VLDATAQRCLDNRRGSCWRRVV 358
+F R + S C G + + ECE G + D Q L + R +
Sbjct: 238 GSF--RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 359 DGQCEAAAPELLLRQECC-----CSVGLAWGSXXXXXXXXXXXXXKG---FAKLDGATCR 410
G + A + EC C +G + G +G C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 411 DVDECALSAELCAGG-TCVNTDGSYRCDCPPGLTLD 445
DVDECA AE C G CVN+ GS+RC+C G D
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Query: 2 TNGGMCTNGICKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAG 59
T G +C+ C NI G F+C C GY G C+D+DEC C C N G
Sbjct: 489 TGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 60 SYTCL---CEPGFAPTAA 74
++ CL C + +AA
Sbjct: 548 AFRCLAFECPENYRRSAA 565
Score = 40.3 bits (90), Expect = 0.014
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 6/56 (10%)
Query: 400 GFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC-----DCPPGLTLDSTGT 449
GF + C D++EC ++SA G TC+NT+GSY C +C G L+ GT
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Score = 37.1 bits (82), Expect = 0.13
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 4/39 (10%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCP 439
+G C+D+DEC C+ TC N G++RC +CP
Sbjct: 519 NGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECP 557
>X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein.
Length = 566
Score = 163 bits (396), Expect = 1e-39
Identities = 113/313 (36%), Positives = 143/313 (45%), Gaps = 33/313 (10%)
Query: 1 MTNGGMCTNG-ICKNIDGGFEC----ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-C 54
+T C G C N G F C C GYE + + C+D+DEC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFIC 279
Query: 55 RNTAGSYTCL----CEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCV---- 104
+NT GS+ C C+ GF A G C D++EC + S C G C+N+EGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 105 -CEAGYRPTATRGACVDVDECEEQ-RVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLG 161
C GY CVDVDEC C G RC N+PGSFRCEC G+ R C+
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 162 LKLGWGVSCQACPAQGSEL---YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ + C + Y C G G DINEC++ P C C N
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECAN 456
Query: 216 LEPGYRCICDPGYH-PDADGL-CRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPE-GTRH 271
+ Y+C C GY D DG+ C DIDEC + + +C N GSF C CP G R
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRL 516
Query: 272 EPELQLCRDIDEC 284
P + C+DIDEC
Sbjct: 517 APNGRNCQDIDEC 529
Score = 142 bits (344), Expect = 2e-33
Identities = 121/377 (32%), Positives = 159/377 (42%), Gaps = 67/377 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
GG C C++ C C GY+ S+G C DV+EC CR G C NT GS+
Sbjct: 183 GGPCKQQ-CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 63 C----LCEPGFAPTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQC----VCEAGYRPT 112
C C G+ T C D+DEC + + C N+ GSF+C C++G+
Sbjct: 242 CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 113 ATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRCE-----CLPGFTLSNDGRTCLGL--- 162
A G C+D++EC C G C NT GS+ C+ C G+ L+ +G C+ +
Sbjct: 302 AL-GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 360
Query: 163 -----KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPG-ACPHGSC 213
G G C P GS + C G D D+NEC PG C H C
Sbjct: 361 APPAEPCGKGHRCVNSP--GS--FRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 214 ENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR-H 271
EN Y C C G+ DG C DI+EC S C+ +C N GS+ C C G +
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLS 472
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ + C DIDEC PT + S RCIN G F+C
Sbjct: 473 DVDGVTCEDIDEC--------------------ALPTGGHICS----YRCINIPGSFQCS 508
Query: 332 C-ELGYVLDATAQRCLD 347
C GY L + C D
Sbjct: 509 CPSSGYRLAPNGRNCQD 525
Score = 107 bits (256), Expect = 1e-22
Identities = 101/362 (27%), Positives = 145/362 (40%), Gaps = 73/362 (20%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSE 179
D C C+ +C +T C C G+ L +DG +C + + SC+ + +
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 180 LYAVLCPEGPS--------KDNGGADINEC-TAVPGACPHGSCENLEPGYRCI----CDP 226
+ + C S +DN DI+EC + + P C+N +RC C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 227 GYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCV-----CPEGTRHEPELQLCRD 280
G+ DA G C DI+EC + C G C NT GS+TC C G E C D
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD 356
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLD 339
+DEC PP A PC G RC+N+ G F CEC+ GY D
Sbjct: 357 VDECA-----------------PP--------AEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 340 ATAQRCLDNRRGSCWR---RVVDGQCE----------AAAPELLLRQECC-----CSVGL 381
++ C+D C R R+ +CE + L + C CS
Sbjct: 392 GISRMCVDVNE--CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP 449
Query: 382 AWGSXXXXXXXXXXXXXKGF--AKLDGATCRDVDECAL--SAELCAGGTCVNTDGSYRCD 437
+G+ + +DG TC D+DECAL +C+ C+N GS++C
Sbjct: 450 CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCS 508
Query: 438 CP 439
CP
Sbjct: 509 CP 510
Score = 97.5 bits (232), Expect = 9e-20
Identities = 54/149 (36%), Positives = 73/149 (48%), Gaps = 13/149 (8%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C + C+N G + C C G+ +G C D++EC +P C + C N GSY C
Sbjct: 408 GRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECANVYGSYQC 463
Query: 64 LCEPGF--APTAAGYCADVDECAADS---MCKGGRCVNSEGSFQCVC-EAGYRPTATRGA 117
C G+ + C D+DECA + +C RC+N GSFQC C +GYR
Sbjct: 464 YCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPNGRN 522
Query: 118 CVDVDECEE--QRVCRNGRCHNTPGSFRC 144
C D+DEC N C N G+FRC
Sbjct: 523 CQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 70.9 bits (166), Expect = 8e-12
Identities = 87/303 (28%), Positives = 109/303 (35%), Gaps = 67/303 (22%)
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHG-SCENLEPGY 220
G G Q C G E+ C G + G D+NEC +C G SC N +
Sbjct: 182 GGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 221 RC----ICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTC----VCPEGTRH 271
RC C GY D C+DIDEC+ C C+NT GSF C C G
Sbjct: 241 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR-CINTHGGFEC 330
+ L C DI+EC +++PC G CINT G + C
Sbjct: 301 DA-LGNCIDINEC-------------------------LSISAPCPIGHTCINTEGSYTC 334
Query: 331 E-----CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
+ C GY L+ RC+D VD +C A C S G
Sbjct: 335 QKNVPNCGRGYHLNEEGTRCVD----------VD-ECAPPAEPCGKGHRCVNSPG----- 378
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G +++ C DV+EC G C NT GSY C C G L
Sbjct: 379 -SFRCECKTGYYFDGISRM----CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLS 433
Query: 446 STG 448
G
Sbjct: 434 VDG 436
Score = 50.4 bits (115), Expect = 1e-05
Identities = 58/216 (26%), Positives = 80/216 (37%), Gaps = 23/216 (10%)
Query: 249 CAGG-----QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP 303
C GG QCR+T C C G + + C D++EC T +H +
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECI--TGSHSCRLGESCINTV 237
Query: 304 PTFPTRTELASPCDNGRCINTHGGFEC--ECELGY---VLDATAQRCLDNRRGSCWRRVV 358
+F R + S C G + + ECE G + D Q L + R +
Sbjct: 238 GSF--RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 359 DGQCEAAAPELLLRQECC-----CSVGLAWGSXXXXXXXXXXXXXKG---FAKLDGATCR 410
G + A + EC C +G + G +G C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 411 DVDECALSAELCAGG-TCVNTDGSYRCDCPPGLTLD 445
DVDECA AE C G CVN+ GS+RC+C G D
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Query: 2 TNGGMCTNGICKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAG 59
T G +C+ C NI G F+C C GY G C+D+DEC C C N G
Sbjct: 489 TGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 60 SYTCL---CEPGFAPTAA 74
++ CL C + +AA
Sbjct: 548 AFRCLAFECPENYRRSAA 565
Score = 40.3 bits (90), Expect = 0.014
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 6/56 (10%)
Query: 400 GFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC-----DCPPGLTLDSTGT 449
GF + C D++EC ++SA G TC+NT+GSY C +C G L+ GT
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Score = 37.1 bits (82), Expect = 0.13
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 4/39 (10%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCP 439
+G C+D+DEC C+ TC N G++RC +CP
Sbjct: 519 NGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECP 557
>U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein.
Length = 703
Score = 163 bits (396), Expect = 1e-39
Identities = 113/313 (36%), Positives = 143/313 (45%), Gaps = 33/313 (10%)
Query: 1 MTNGGMCTNG-ICKNIDGGFEC----ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-C 54
+T C G C N G F C C GYE + + C+D+DEC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFIC 279
Query: 55 RNTAGSYTCL----CEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCV---- 104
+NT GS+ C C+ GF A G C D++EC + S C G C+N+EGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 105 -CEAGYRPTATRGACVDVDECEEQ-RVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLG 161
C GY CVDVDEC C G RC N+PGSFRCEC G+ R C+
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 162 LKLGWGVSCQACPAQGSEL---YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ + C + Y C G G DINEC++ P C C N
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECAN 456
Query: 216 LEPGYRCICDPGYH-PDADGL-CRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPE-GTRH 271
+ Y+C C GY D DG+ C DIDEC + + +C N GSF C CP G R
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRL 516
Query: 272 EPELQLCRDIDEC 284
P + C+DIDEC
Sbjct: 517 APNGRNCQDIDEC 529
Score = 142 bits (344), Expect = 2e-33
Identities = 121/377 (32%), Positives = 159/377 (42%), Gaps = 67/377 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
GG C C++ C C GY+ S+G C DV+EC CR G C NT GS+
Sbjct: 183 GGPCKQQ-CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 63 C----LCEPGFAPTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQC----VCEAGYRPT 112
C C G+ T C D+DEC + + C N+ GSF+C C++G+
Sbjct: 242 CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 113 ATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRCE-----CLPGFTLSNDGRTCLGL--- 162
A G C+D++EC C G C NT GS+ C+ C G+ L+ +G C+ +
Sbjct: 302 AL-GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 360
Query: 163 -----KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPG-ACPHGSC 213
G G C P GS + C G D D+NEC PG C H C
Sbjct: 361 APPAEPCGKGHRCVNSP--GS--FRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 214 ENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR-H 271
EN Y C C G+ DG C DI+EC S C+ +C N GS+ C C G +
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLS 472
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ + C DIDEC PT + S RCIN G F+C
Sbjct: 473 DVDGVTCEDIDEC--------------------ALPTGGHICS----YRCINIPGSFQCS 508
Query: 332 C-ELGYVLDATAQRCLD 347
C GY L + C D
Sbjct: 509 CPSSGYRLAPNGRNCQD 525
Score = 107 bits (256), Expect = 1e-22
Identities = 101/362 (27%), Positives = 145/362 (40%), Gaps = 73/362 (20%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSE 179
D C C+ +C +T C C G+ L +DG +C + + SC+ + +
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 180 LYAVLCPEGPS--------KDNGGADINEC-TAVPGACPHGSCENLEPGYRCI----CDP 226
+ + C S +DN DI+EC + + P C+N +RC C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 227 GYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCV-----CPEGTRHEPELQLCRD 280
G+ DA G C DI+EC + C G C NT GS+TC C G E C D
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD 356
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLD 339
+DEC PP A PC G RC+N+ G F CEC+ GY D
Sbjct: 357 VDECA-----------------PP--------AEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 340 ATAQRCLDNRRGSCWR---RVVDGQCE----------AAAPELLLRQECC-----CSVGL 381
++ C+D C R R+ +CE + L + C CS
Sbjct: 392 GISRMCVDVNE--CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP 449
Query: 382 AWGSXXXXXXXXXXXXXKGF--AKLDGATCRDVDECAL--SAELCAGGTCVNTDGSYRCD 437
+G+ + +DG TC D+DECAL +C+ C+N GS++C
Sbjct: 450 CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCS 508
Query: 438 CP 439
CP
Sbjct: 509 CP 510
Score = 97.5 bits (232), Expect = 9e-20
Identities = 54/149 (36%), Positives = 73/149 (48%), Gaps = 13/149 (8%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C + C+N G + C C G+ +G C D++EC +P C + C N GSY C
Sbjct: 408 GRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECANVYGSYQC 463
Query: 64 LCEPGF--APTAAGYCADVDECAADS---MCKGGRCVNSEGSFQCVC-EAGYRPTATRGA 117
C G+ + C D+DECA + +C RC+N GSFQC C +GYR
Sbjct: 464 YCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPNGRN 522
Query: 118 CVDVDECEE--QRVCRNGRCHNTPGSFRC 144
C D+DEC N C N G+FRC
Sbjct: 523 CQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 70.9 bits (166), Expect = 8e-12
Identities = 87/303 (28%), Positives = 109/303 (35%), Gaps = 67/303 (22%)
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHG-SCENLEPGY 220
G G Q C G E+ C G + G D+NEC +C G SC N +
Sbjct: 182 GGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 221 RC----ICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTC----VCPEGTRH 271
RC C GY D C+DIDEC+ C C+NT GSF C C G
Sbjct: 241 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR-CINTHGGFEC 330
+ L C DI+EC +++PC G CINT G + C
Sbjct: 301 DA-LGNCIDINEC-------------------------LSISAPCPIGHTCINTEGSYTC 334
Query: 331 E-----CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
+ C GY L+ RC+D VD +C A C S G
Sbjct: 335 QKNVPNCGRGYHLNEEGTRCVD----------VD-ECAPPAEPCGKGHRCVNSPG----- 378
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G +++ C DV+EC G C NT GSY C C G L
Sbjct: 379 -SFRCECKTGYYFDGISRM----CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLS 433
Query: 446 STG 448
G
Sbjct: 434 VDG 436
Score = 50.4 bits (115), Expect = 1e-05
Identities = 58/216 (26%), Positives = 80/216 (37%), Gaps = 23/216 (10%)
Query: 249 CAGG-----QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP 303
C GG QCR+T C C G + + C D++EC T +H +
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECI--TGSHSCRLGESCINTV 237
Query: 304 PTFPTRTELASPCDNGRCINTHGGFEC--ECELGY---VLDATAQRCLDNRRGSCWRRVV 358
+F R + S C G + + ECE G + D Q L + R +
Sbjct: 238 GSF--RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 359 DGQCEAAAPELLLRQECC-----CSVGLAWGSXXXXXXXXXXXXXKG---FAKLDGATCR 410
G + A + EC C +G + G +G C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 411 DVDECALSAELCAGG-TCVNTDGSYRCDCPPGLTLD 445
DVDECA AE C G CVN+ GS+RC+C G D
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Query: 2 TNGGMCTNGICKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAG 59
T G +C+ C NI G F+C C GY G C+D+DEC C C N G
Sbjct: 489 TGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 60 SYTCL---CEPGFAPTAA 74
++ CL C + +AA
Sbjct: 548 AFRCLAFECPENYRRSAA 565
Score = 40.3 bits (90), Expect = 0.014
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 6/56 (10%)
Query: 400 GFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC-----DCPPGLTLDSTGT 449
GF + C D++EC ++SA G TC+NT+GSY C +C G L+ GT
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Score = 37.1 bits (82), Expect = 0.13
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 4/39 (10%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCP 439
+G C+D+DEC C+ TC N G++RC +CP
Sbjct: 519 NGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECP 557
>AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 163 bits (396), Expect = 1e-39
Identities = 113/313 (36%), Positives = 143/313 (45%), Gaps = 33/313 (10%)
Query: 1 MTNGGMCTNG-ICKNIDGGFEC----ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-C 54
+T C G C N G F C C GYE + + C+D+DEC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFIC 279
Query: 55 RNTAGSYTCL----CEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCV---- 104
+NT GS+ C C+ GF A G C D++EC + S C G C+N+EGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 105 -CEAGYRPTATRGACVDVDECEEQ-RVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLG 161
C GY CVDVDEC C G RC N+PGSFRCEC G+ R C+
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 162 LKLGWGVSCQACPAQGSEL---YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ + C + Y C G G DINEC++ P C C N
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECAN 456
Query: 216 LEPGYRCICDPGYH-PDADGL-CRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPE-GTRH 271
+ Y+C C GY D DG+ C DIDEC + + +C N GSF C CP G R
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRL 516
Query: 272 EPELQLCRDIDEC 284
P + C+DIDEC
Sbjct: 517 APNGRNCQDIDEC 529
Score = 142 bits (344), Expect = 2e-33
Identities = 121/377 (32%), Positives = 159/377 (42%), Gaps = 67/377 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
GG C C++ C C GY+ S+G C DV+EC CR G C NT GS+
Sbjct: 183 GGPCKQQ-CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 63 C----LCEPGFAPTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQC----VCEAGYRPT 112
C C G+ T C D+DEC + + C N+ GSF+C C++G+
Sbjct: 242 CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 113 ATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRCE-----CLPGFTLSNDGRTCLGL--- 162
A G C+D++EC C G C NT GS+ C+ C G+ L+ +G C+ +
Sbjct: 302 AL-GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 360
Query: 163 -----KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPG-ACPHGSC 213
G G C P GS + C G D D+NEC PG C H C
Sbjct: 361 APPAEPCGKGHRCVNSP--GS--FRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 214 ENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR-H 271
EN Y C C G+ DG C DI+EC S C+ +C N GS+ C C G +
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLS 472
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ + C DIDEC PT + S RCIN G F+C
Sbjct: 473 DVDGVTCEDIDEC--------------------ALPTGGHICS----YRCINIPGSFQCS 508
Query: 332 C-ELGYVLDATAQRCLD 347
C GY L + C D
Sbjct: 509 CPSSGYRLAPNGRNCQD 525
Score = 114 bits (274), Expect = 7e-25
Identities = 79/245 (32%), Positives = 113/245 (46%), Gaps = 29/245 (11%)
Query: 12 CKNIDGGFECI-----CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLC 65
C N +G + C C GY EG C DVDEC C +G RC N+ GS+ C C
Sbjct: 325 CINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 384
Query: 66 EPGFA-PTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+ G+ + C DV+EC +C G +C N+ GS+ C C G+R + +C D++
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLC-GHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN 443
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN-DGRTC-----LGLKLGWGVSCQAC-PA 175
EC + C N GS++C C G+ LS+ DG TC L G + C
Sbjct: 444 ECSSSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINI 501
Query: 176 QGSELYAVLCPEGPSK--DNGG--ADINEC-TAVPGACPHGSCENLEPGYRCI---CDPG 227
GS + CP + NG DI+EC T + + +C N++ G+RC+ C
Sbjct: 502 PGS--FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPEN 559
Query: 228 YHPDA 232
Y A
Sbjct: 560 YRRSA 564
Score = 107 bits (256), Expect = 1e-22
Identities = 101/362 (27%), Positives = 145/362 (40%), Gaps = 73/362 (20%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSE 179
D C C+ +C +T C C G+ L +DG +C + + SC+ + +
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 180 LYAVLCPEGPS--------KDNGGADINEC-TAVPGACPHGSCENLEPGYRCI----CDP 226
+ + C S +DN DI+EC + + P C+N +RC C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 227 GYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCV-----CPEGTRHEPELQLCRD 280
G+ DA G C DI+EC + C G C NT GS+TC C G E C D
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD 356
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLD 339
+DEC PP A PC G RC+N+ G F CEC+ GY D
Sbjct: 357 VDECA-----------------PP--------AEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 340 ATAQRCLDNRRGSCWR---RVVDGQCE----------AAAPELLLRQECC-----CSVGL 381
++ C+D C R R+ +CE + L + C CS
Sbjct: 392 GISRMCVDVNE--CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP 449
Query: 382 AWGSXXXXXXXXXXXXXKGF--AKLDGATCRDVDECAL--SAELCAGGTCVNTDGSYRCD 437
+G+ + +DG TC D+DECAL +C+ C+N GS++C
Sbjct: 450 CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCS 508
Query: 438 CP 439
CP
Sbjct: 509 CP 510
Score = 70.9 bits (166), Expect = 8e-12
Identities = 87/303 (28%), Positives = 109/303 (35%), Gaps = 67/303 (22%)
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHG-SCENLEPGY 220
G G Q C G E+ C G + G D+NEC +C G SC N +
Sbjct: 182 GGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 221 RC----ICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTC----VCPEGTRH 271
RC C GY D C+DIDEC+ C C+NT GSF C C G
Sbjct: 241 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR-CINTHGGFEC 330
+ L C DI+EC +++PC G CINT G + C
Sbjct: 301 DA-LGNCIDINEC-------------------------LSISAPCPIGHTCINTEGSYTC 334
Query: 331 E-----CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
+ C GY L+ RC+D VD +C A C S G
Sbjct: 335 QKNVPNCGRGYHLNEEGTRCVD----------VD-ECAPPAEPCGKGHRCVNSPG----- 378
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G +++ C DV+EC G C NT GSY C C G L
Sbjct: 379 -SFRCECKTGYYFDGISRM----CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLS 433
Query: 446 STG 448
G
Sbjct: 434 VDG 436
Score = 50.4 bits (115), Expect = 1e-05
Identities = 58/216 (26%), Positives = 80/216 (37%), Gaps = 23/216 (10%)
Query: 249 CAGG-----QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP 303
C GG QCR+T C C G + + C D++EC T +H +
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECI--TGSHSCRLGESCINTV 237
Query: 304 PTFPTRTELASPCDNGRCINTHGGFEC--ECELGY---VLDATAQRCLDNRRGSCWRRVV 358
+F R + S C G + + ECE G + D Q L + R +
Sbjct: 238 GSF--RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 359 DGQCEAAAPELLLRQECC-----CSVGLAWGSXXXXXXXXXXXXXKG---FAKLDGATCR 410
G + A + EC C +G + G +G C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 411 DVDECALSAELCAGG-TCVNTDGSYRCDCPPGLTLD 445
DVDECA AE C G CVN+ GS+RC+C G D
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 46.4 bits (105), Expect = 2e-04
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 6/78 (7%)
Query: 2 TNGGMCTNGICKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAG 59
T G +C+ C NI G F+C C GY G C+D+DEC C C N G
Sbjct: 489 TGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 60 SYTCL---CEPGFAPTAA 74
+ CL C + +AA
Sbjct: 548 GFRCLAFECPENYRRSAA 565
Score = 40.3 bits (90), Expect = 0.014
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 6/56 (10%)
Query: 400 GFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC-----DCPPGLTLDSTGT 449
GF + C D++EC ++SA G TC+NT+GSY C +C G L+ GT
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Score = 36.7 bits (81), Expect = 0.17
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCP 439
+G C+D+DEC C+ TC N G +RC +CP
Sbjct: 519 NGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 557
>AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens
cDNA PSEC0266 fis, clone NT2RP3003649, highly similar to
Homo sapiens fibulin-1D mRNA. ).
Length = 638
Score = 163 bits (396), Expect = 1e-39
Identities = 113/313 (36%), Positives = 143/313 (45%), Gaps = 33/313 (10%)
Query: 1 MTNGGMCTNG-ICKNIDGGFEC----ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-C 54
+T C G C N G F C C GYE + + C+D+DEC C C
Sbjct: 156 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFIC 214
Query: 55 RNTAGSYTCL----CEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCV---- 104
+NT GS+ C C+ GF A G C D++EC + S C G C+N+EGS+ C
Sbjct: 215 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 274
Query: 105 -CEAGYRPTATRGACVDVDECEEQ-RVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLG 161
C GY CVDVDEC C G RC N+PGSFRCEC G+ R C+
Sbjct: 275 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 334
Query: 162 LKLGWGVSCQACPAQGSEL---YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ + C + Y C G G DINEC++ P C C N
Sbjct: 335 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECAN 391
Query: 216 LEPGYRCICDPGYH-PDADGL-CRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPE-GTRH 271
+ Y+C C GY D DG+ C DIDEC + + +C N GSF C CP G R
Sbjct: 392 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRL 451
Query: 272 EPELQLCRDIDEC 284
P + C+DIDEC
Sbjct: 452 APNGRNCQDIDEC 464
Score = 142 bits (344), Expect = 2e-33
Identities = 121/377 (32%), Positives = 159/377 (42%), Gaps = 67/377 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
GG C C++ C C GY+ S+G C DV+EC CR G C NT GS+
Sbjct: 118 GGPCKQQ-CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 176
Query: 63 C----LCEPGFAPTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQC----VCEAGYRPT 112
C C G+ T C D+DEC + + C N+ GSF+C C++G+
Sbjct: 177 CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 236
Query: 113 ATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRCE-----CLPGFTLSNDGRTCLGL--- 162
A G C+D++EC C G C NT GS+ C+ C G+ L+ +G C+ +
Sbjct: 237 AL-GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 295
Query: 163 -----KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPG-ACPHGSC 213
G G C P GS + C G D D+NEC PG C H C
Sbjct: 296 APPAEPCGKGHRCVNSP--GS--FRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 350
Query: 214 ENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR-H 271
EN Y C C G+ DG C DI+EC S C+ +C N GS+ C C G +
Sbjct: 351 ENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLS 407
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ + C DIDEC PT + S RCIN G F+C
Sbjct: 408 DVDGVTCEDIDEC--------------------ALPTGGHICS----YRCINIPGSFQCS 443
Query: 332 C-ELGYVLDATAQRCLD 347
C GY L + C D
Sbjct: 444 CPSSGYRLAPNGRNCQD 460
Score = 114 bits (274), Expect = 7e-25
Identities = 79/245 (32%), Positives = 113/245 (46%), Gaps = 29/245 (11%)
Query: 12 CKNIDGGFECI-----CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLC 65
C N +G + C C GY EG C DVDEC C +G RC N+ GS+ C C
Sbjct: 260 CINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 319
Query: 66 EPGFA-PTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+ G+ + C DV+EC +C G +C N+ GS+ C C G+R + +C D++
Sbjct: 320 KTGYYFDGISRMCVDVNECQRYPGRLC-GHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN 378
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN-DGRTC-----LGLKLGWGVSCQAC-PA 175
EC + C N GS++C C G+ LS+ DG TC L G + C
Sbjct: 379 ECSSSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINI 436
Query: 176 QGSELYAVLCPEGPSK--DNGG--ADINEC-TAVPGACPHGSCENLEPGYRCI---CDPG 227
GS + CP + NG DI+EC T + + +C N++ G+RC+ C
Sbjct: 437 PGS--FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPEN 494
Query: 228 YHPDA 232
Y A
Sbjct: 495 YRRSA 499
Score = 107 bits (256), Expect = 1e-22
Identities = 101/362 (27%), Positives = 145/362 (40%), Gaps = 73/362 (20%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSE 179
D C C+ +C +T C C G+ L +DG +C + + SC+ + +
Sbjct: 113 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 171
Query: 180 LYAVLCPEGPS--------KDNGGADINEC-TAVPGACPHGSCENLEPGYRCI----CDP 226
+ + C S +DN DI+EC + + P C+N +RC C
Sbjct: 172 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 231
Query: 227 GYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCV-----CPEGTRHEPELQLCRD 280
G+ DA G C DI+EC + C G C NT GS+TC C G E C D
Sbjct: 232 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD 291
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLD 339
+DEC PP A PC G RC+N+ G F CEC+ GY D
Sbjct: 292 VDECA-----------------PP--------AEPCGKGHRCVNSPGSFRCECKTGYYFD 326
Query: 340 ATAQRCLDNRRGSCWR---RVVDGQCE----------AAAPELLLRQECC-----CSVGL 381
++ C+D C R R+ +CE + L + C CS
Sbjct: 327 GISRMCVDVNE--CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP 384
Query: 382 AWGSXXXXXXXXXXXXXKGF--AKLDGATCRDVDECAL--SAELCAGGTCVNTDGSYRCD 437
+G+ + +DG TC D+DECAL +C+ C+N GS++C
Sbjct: 385 CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCS 443
Query: 438 CP 439
CP
Sbjct: 444 CP 445
Score = 70.9 bits (166), Expect = 8e-12
Identities = 87/303 (28%), Positives = 109/303 (35%), Gaps = 67/303 (22%)
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHG-SCENLEPGY 220
G G Q C G E+ C G + G D+NEC +C G SC N +
Sbjct: 117 GGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 175
Query: 221 RC----ICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTC----VCPEGTRH 271
RC C GY D C+DIDEC+ C C+NT GSF C C G
Sbjct: 176 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 235
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR-CINTHGGFEC 330
+ L C DI+EC +++PC G CINT G + C
Sbjct: 236 DA-LGNCIDINEC-------------------------LSISAPCPIGHTCINTEGSYTC 269
Query: 331 E-----CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
+ C GY L+ RC+D VD +C A C S G
Sbjct: 270 QKNVPNCGRGYHLNEEGTRCVD----------VD-ECAPPAEPCGKGHRCVNSPG----- 313
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G +++ C DV+EC G C NT GSY C C G L
Sbjct: 314 -SFRCECKTGYYFDGISRM----CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLS 368
Query: 446 STG 448
G
Sbjct: 369 VDG 371
Score = 50.4 bits (115), Expect = 1e-05
Identities = 58/216 (26%), Positives = 80/216 (37%), Gaps = 23/216 (10%)
Query: 249 CAGG-----QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP 303
C GG QCR+T C C G + + C D++EC T +H +
Sbjct: 115 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECI--TGSHSCRLGESCINTV 172
Query: 304 PTFPTRTELASPCDNGRCINTHGGFEC--ECELGY---VLDATAQRCLDNRRGSCWRRVV 358
+F R + S C G + + ECE G + D Q L + R +
Sbjct: 173 GSF--RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 230
Query: 359 DGQCEAAAPELLLRQECC-----CSVGLAWGSXXXXXXXXXXXXXKG---FAKLDGATCR 410
G + A + EC C +G + G +G C
Sbjct: 231 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 290
Query: 411 DVDECALSAELCAGG-TCVNTDGSYRCDCPPGLTLD 445
DVDECA AE C G CVN+ GS+RC+C G D
Sbjct: 291 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 326
Score = 46.4 bits (105), Expect = 2e-04
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 6/78 (7%)
Query: 2 TNGGMCTNGICKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAG 59
T G +C+ C NI G F+C C GY G C+D+DEC C C N G
Sbjct: 424 TGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 482
Query: 60 SYTCL---CEPGFAPTAA 74
+ CL C + +AA
Sbjct: 483 GFRCLAFECPENYRRSAA 500
Score = 40.3 bits (90), Expect = 0.014
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 6/56 (10%)
Query: 400 GFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC-----DCPPGLTLDSTGT 449
GF + C D++EC ++SA G TC+NT+GSY C +C G L+ GT
Sbjct: 232 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 287
Score = 36.7 bits (81), Expect = 0.17
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCP 439
+G C+D+DEC C+ TC N G +RC +CP
Sbjct: 454 NGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 492
>AF525689-1|AAN77133.1| 988|Homo sapiens signal
peptide-CUB-EGF-like domain containing protein 1
protein.
Length = 988
Score = 163 bits (396), Expect = 1e-39
Identities = 117/374 (31%), Positives = 167/374 (44%), Gaps = 36/374 (9%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDN--PRVCRRGRCRNTAGSYTCLCE 66
+ IC+N ++C+CKPGY+ EG C D+DEC ++ C C N G+Y C C
Sbjct: 47 DAICQNAPKSYKCLCKPGYKG--EGKQCGDIDECENDYYNGGCVH-ECINIPGNYRCTCF 103
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF G+ C DVDEC ++ CVN+ GS++C C +G+ + + C+
Sbjct: 104 DGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIH--RSN 161
Query: 126 EQRVCRNGR------CHNTP-GSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQACPAQG 177
E C N C TP G C+C PGF L+ + + C L G G +C
Sbjct: 162 EGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTD 221
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LC 236
+ + +G I C G C +C++ G RC C G+ DG C
Sbjct: 222 TGPTCGCHQKYAPHSDGRTCIETCAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTC 280
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI--- 293
+DI+EC ++ C CRNT GSF C C +G + + + C+DIDEC E +I
Sbjct: 281 KDINECLVNNGGC-DHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICIN 339
Query: 294 -----ESDYERGDI--PPTFPTRTELAS----PCDNGRCINTHGGFECECELGYVLDATA 342
+ RG I T + S CD G C+NT G +EC C G L
Sbjct: 340 SPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNR 398
Query: 343 QRCLDNRRGSCWRR 356
+ C++ G C R
Sbjct: 399 KDCVET--GKCLSR 410
Score = 152 bits (368), Expect = 3e-36
Identities = 132/431 (30%), Positives = 172/431 (39%), Gaps = 77/431 (17%)
Query: 29 SGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVDECAADS 87
SG G++ DVDEC + C C+N SY CLC+PG+ C D+DEC D
Sbjct: 26 SGLPGSV--DVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGEGK-QCGDIDECENDY 82
Query: 88 MCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCE 145
G C+N G+++C C G+ C+DVDEC++ C N GS+ C+
Sbjct: 83 YNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQ 142
Query: 146 CLPGFTLS----------NDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG 195
C GF LS N+G C+ G C+ P G A C G
Sbjct: 143 CHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGG---VACDCRPGFDLAQNQ 199
Query: 196 ADIN-ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQ 253
D C G C H SCE+ + G C C Y P +DG C I+ C ++ C
Sbjct: 200 KDCTLTCNYGNGGCQH-SCEDTDTGPTCGCHQKYAPHSDGRTC--IETCAVNNGGC-DRT 255
Query: 254 CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELA 313
C++TA C CP G +P+ G+T E G
Sbjct: 256 CKDTATGVRCSCPVGFTLQPD-----------GKTCKDINECLVNNGG------------ 292
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
CD+ C NT G FEC C GY L + C D S + R D C +
Sbjct: 293 --CDHF-CRNTVGSFECGCRKGYKLLTDERTCQDIDECS-FERTCDHICINSPGSF---- 344
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGS 433
+C C +G+ C DVDEC++S C G CVNT GS
Sbjct: 345 QCLCH--------------------RGYILYGTTHCGDVDECSMSNGSCDQG-CVNTKGS 383
Query: 434 YRCDCPPGLTL 444
Y C CPPG L
Sbjct: 384 YECVCPPGRRL 394
Score = 118 bits (283), Expect = 6e-26
Identities = 88/292 (30%), Positives = 115/292 (39%), Gaps = 19/292 (6%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C NI G + C C G+ +G C DVDEC+DN C++ C N GSY
Sbjct: 84 NGG-CVHE-CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYE 140
Query: 63 CLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVN-----SEGSFQCVCEAGYRPTATRG 116
C C GF + + C + M K C + +G C C G+ +
Sbjct: 141 CQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQK 200
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
C C C +T C C + +DGRTC+ C
Sbjct: 201 DCTLT--CNYGNGGCQHSCEDTDTGPTCGCHQKYAPHSDGRTCIETCAVNNGGCDRTCKD 258
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ CP G + G DINEC G C H C N + C C GY D
Sbjct: 259 TATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH-FCRNTVGSFECGCRKGYKLLTD 317
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C+DIDEC ++ C N+ GSF C+C G C D+DEC
Sbjct: 318 ERTCQDIDECSFERT--CDHICINSPGSFQCLCHRGYILYGTTH-CGDVDEC 366
Score = 114 bits (274), Expect = 7e-25
Identities = 61/159 (38%), Positives = 79/159 (49%), Gaps = 5/159 (3%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G C CK+ G C C G+ +G C+D++EC N C CRNT GS+
Sbjct: 248 NNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHF-CRNTVGSFE 305
Query: 63 CLCEPGFAP-TAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C G+ T C D+DEC+ + C C+NS GSFQC+C GY T C DV
Sbjct: 306 CGCRKGYKLLTDERTCQDIDECSFERTCDH-ICINSPGSFQCLCHRGYILYGTTH-CGDV 363
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
DEC + C NT GS+ C C PG L + + C+
Sbjct: 364 DECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNRKDCV 402
Score = 106 bits (254), Expect = 2e-22
Identities = 82/298 (27%), Positives = 114/298 (38%), Gaps = 18/298 (6%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC----RDVDECRDNPRVCRRGRCRNTA 58
N G C IC N G +EC C G+ C + C + C CR T
Sbjct: 124 NNGGCQQ-ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH-ICRETP 181
Query: 59 -GSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
G C C PGF + + C+ C +++ C C Y P +
Sbjct: 182 KGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHS-CEDTDTGPTCGCHQKYAPHSDGRT 240
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPA 175
C++ C + C +T RC C GFTL DG+TC + L C
Sbjct: 241 CIET--CAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCR 298
Query: 176 QGSELYAVLCPEGP---SKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
+ C +G + + DI+EC+ C H C N ++C+C GY
Sbjct: 299 NTVGSFECGCRKGYKLLTDERTCQDIDECS-FERTCDH-ICINSPGSFQCLCHRGYILYG 356
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
C D+DEC M C G C NT GS+ CVCP G R + C + +C +T
Sbjct: 357 TTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNRKDCVETGKCLSRAKT 413
Score = 101 bits (243), Expect = 4e-21
Identities = 49/125 (39%), Positives = 71/125 (56%), Gaps = 5/125 (4%)
Query: 1 MTNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGS 60
+ N G C + C+N G FEC C+ GY+ ++ C+D+DEC R C C N+ GS
Sbjct: 287 LVNNGGCDH-FCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFE-RTCDH-ICINSPGS 343
Query: 61 YTCLCEPGFAPTAAGYCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
+ CLC G+ +C DVDEC+ ++ C G CVN++GS++CVC G R R CV
Sbjct: 344 FQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNRKDCV 402
Query: 120 DVDEC 124
+ +C
Sbjct: 403 ETGKC 407
Score = 64.5 bits (150), Expect = 7e-10
Identities = 92/359 (25%), Positives = 135/359 (37%), Gaps = 63/359 (17%)
Query: 119 VDVDECEEQRV-CR-NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK------LGWGVSC 170
VDVDEC E C + C N P S++C C PG+ +G+ C + G
Sbjct: 32 VDVDECSEGTDDCHIDAICQNAPKSYKCLCKPGY--KGEGKQCGDIDECENDYYNGGCVH 89
Query: 171 QACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPG 227
+ G+ Y C +G + G D++EC G C C N Y C C G
Sbjct: 90 ECINIPGN--YRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSG 146
Query: 228 YH-PDADGLC--RDIDECD-MHQSYCAGGQCRNTA-GSFTCVCPEG---TRHEPELQLCR 279
+ D C R + + M++ + CR T G C C G +++ + L
Sbjct: 147 FFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTC 206
Query: 280 DIDE------CEGETETHYIESDYER----GDIPPTFPTRTELASPCDNGRCINTHGGFE 329
+ CE +T+T +++ D T CD C +T G
Sbjct: 207 NYGNGGCQHSCE-DTDTGPTCGCHQKYAPHSDGRTCIETCAVNNGGCDR-TCKDTATGVR 264
Query: 330 CECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXX 389
C C +G+ L + C D C V +G C+ + EC C
Sbjct: 265 CSCPVGFTLQPDGKTCKDINE--CL--VNNGGCDHFCRNTVGSFECGCR----------- 309
Query: 390 XXXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
KG+ L D TC+D+DEC S E C+N+ GS++C C G L T
Sbjct: 310 ---------KGYKLLTDERTCQDIDEC--SFERTCDHICINSPGSFQCLCHRGYILYGT 357
Score = 48.0 bits (109), Expect = 7e-05
Identities = 62/250 (24%), Positives = 91/250 (36%), Gaps = 44/250 (17%)
Query: 238 DIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET-------E 289
D+DEC C C+N S+ C+C G ++ E + C DIDECE + E
Sbjct: 33 DVDECSEGTDDCHIDAICQNAPKSYKCLCKPG--YKGEGKQCGDIDECENDYYNGGCVHE 90
Query: 290 THYIESDYE----RGDIPPTFPTRTELASPC--DNGRC----INTHGGFECECELGYVLD 339
I +Y G + C +NG C +N G +EC+C G+ L
Sbjct: 91 CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLS 150
Query: 340 ATAQRCLD---------NRRGSC---WRRVVDG--QCEAAAPELLLRQECCCSVGLAWGS 385
C+ N+ C R G C+ L + + C++ +G+
Sbjct: 151 DNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGN 210
Query: 386 XXXXXXXXXXXXX-------KGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
K DG TC ++ CA++ C TC +T RC C
Sbjct: 211 GGCQHSCEDTDTGPTCGCHQKYAPHSDGRTC--IETCAVNNGGC-DRTCKDTATGVRCSC 267
Query: 439 PPGLTLDSTG 448
P G TL G
Sbjct: 268 PVGFTLQPDG 277
>AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein.
Length = 495
Score = 163 bits (396), Expect = 1e-39
Identities = 113/313 (36%), Positives = 143/313 (45%), Gaps = 33/313 (10%)
Query: 1 MTNGGMCTNG-ICKNIDGGFEC----ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-C 54
+T C G C N G F C C GYE + + C+D+DEC C C
Sbjct: 91 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFIC 149
Query: 55 RNTAGSYTCL----CEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCV---- 104
+NT GS+ C C+ GF A G C D++EC + S C G C+N+EGS+ C
Sbjct: 150 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 209
Query: 105 -CEAGYRPTATRGACVDVDECEEQ-RVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLG 161
C GY CVDVDEC C G RC N+PGSFRCEC G+ R C+
Sbjct: 210 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 269
Query: 162 LKLGWGVSCQACPAQGSEL---YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ + C + Y C G G DINEC++ P C C N
Sbjct: 270 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECAN 326
Query: 216 LEPGYRCICDPGYH-PDADGL-CRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPE-GTRH 271
+ Y+C C GY D DG+ C DIDEC + + +C N GSF C CP G R
Sbjct: 327 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRL 386
Query: 272 EPELQLCRDIDEC 284
P + C+DIDEC
Sbjct: 387 APNGRNCQDIDEC 399
Score = 142 bits (344), Expect = 2e-33
Identities = 121/377 (32%), Positives = 159/377 (42%), Gaps = 67/377 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
GG C C++ C C GY+ S+G C DV+EC CR G C NT GS+
Sbjct: 53 GGPCKQQ-CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 111
Query: 63 C----LCEPGFAPTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQC----VCEAGYRPT 112
C C G+ T C D+DEC + + C N+ GSF+C C++G+
Sbjct: 112 CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 171
Query: 113 ATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRCE-----CLPGFTLSNDGRTCLGL--- 162
A G C+D++EC C G C NT GS+ C+ C G+ L+ +G C+ +
Sbjct: 172 AL-GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 230
Query: 163 -----KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPG-ACPHGSC 213
G G C P GS + C G D D+NEC PG C H C
Sbjct: 231 APPAEPCGKGHRCVNSP--GS--FRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 285
Query: 214 ENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR-H 271
EN Y C C G+ DG C DI+EC S C+ +C N GS+ C C G +
Sbjct: 286 ENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLS 342
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ + C DIDEC PT + S RCIN G F+C
Sbjct: 343 DVDGVTCEDIDEC--------------------ALPTGGHICS----YRCINIPGSFQCS 378
Query: 332 C-ELGYVLDATAQRCLD 347
C GY L + C D
Sbjct: 379 CPSSGYRLAPNGRNCQD 395
Score = 115 bits (277), Expect = 3e-25
Identities = 80/249 (32%), Positives = 114/249 (45%), Gaps = 29/249 (11%)
Query: 12 CKNIDGGFECI-----CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLC 65
C N +G + C C GY EG C DVDEC C +G RC N+ GS+ C C
Sbjct: 195 CINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 254
Query: 66 EPGFA-PTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+ G+ + C DV+EC +C G +C N+ GS+ C C G+R + +C D++
Sbjct: 255 KTGYYFDGISRMCVDVNECQRYPGRLC-GHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN 313
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN-DGRTC-----LGLKLGWGVSCQAC-PA 175
EC + C N GS++C C G+ LS+ DG TC L G + C
Sbjct: 314 ECSSSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINI 371
Query: 176 QGSELYAVLCPEGPSK--DNGG--ADINEC-TAVPGACPHGSCENLEPGYRCI---CDPG 227
GS + CP + NG DI+EC T + + +C N++ G+RC+ C
Sbjct: 372 PGS--FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPEN 429
Query: 228 YHPDADGLC 236
Y A C
Sbjct: 430 YRRSAATRC 438
Score = 111 bits (268), Expect = 4e-24
Identities = 75/220 (34%), Positives = 101/220 (45%), Gaps = 35/220 (15%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNP-RVCRRGRCRNTAGSYTCLCEPGFA 70
C N G F C CK GY +C DV+EC+ P R+C +C NT GSY C C GF
Sbjct: 243 CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFR 301
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDECEEQ- 127
+ G C D++EC++ S C C N GS+QC C GY+ + G C D+DEC
Sbjct: 302 LSVDGRSCEDINECSS-SPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 359
Query: 128 --RVCRNGRCHNTPGSFRCEC-LPGFTLSNDGR-------------------TCLGLKLG 165
+C + RC N PGSF+C C G+ L+ +GR TC ++ G
Sbjct: 360 GGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGG 418
Query: 166 WGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVP 205
+ CP A C P +N EC+ +P
Sbjct: 419 FRCLAFECPENYRRSAATRCERLPCHEN-----RECSKLP 453
Score = 107 bits (256), Expect = 1e-22
Identities = 101/362 (27%), Positives = 145/362 (40%), Gaps = 73/362 (20%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSE 179
D C C+ +C +T C C G+ L +DG +C + + SC+ + +
Sbjct: 48 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 106
Query: 180 LYAVLCPEGPS--------KDNGGADINEC-TAVPGACPHGSCENLEPGYRCI----CDP 226
+ + C S +DN DI+EC + + P C+N +RC C
Sbjct: 107 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 166
Query: 227 GYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCV-----CPEGTRHEPELQLCRD 280
G+ DA G C DI+EC + C G C NT GS+TC C G E C D
Sbjct: 167 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD 226
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLD 339
+DEC PP A PC G RC+N+ G F CEC+ GY D
Sbjct: 227 VDECA-----------------PP--------AEPCGKGHRCVNSPGSFRCECKTGYYFD 261
Query: 340 ATAQRCLDNRRGSCWR---RVVDGQCE----------AAAPELLLRQECC-----CSVGL 381
++ C+D C R R+ +CE + L + C CS
Sbjct: 262 GISRMCVDVNE--CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP 319
Query: 382 AWGSXXXXXXXXXXXXXKGF--AKLDGATCRDVDECAL--SAELCAGGTCVNTDGSYRCD 437
+G+ + +DG TC D+DECAL +C+ C+N GS++C
Sbjct: 320 CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCS 378
Query: 438 CP 439
CP
Sbjct: 379 CP 380
Score = 70.9 bits (166), Expect = 8e-12
Identities = 87/303 (28%), Positives = 109/303 (35%), Gaps = 67/303 (22%)
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHG-SCENLEPGY 220
G G Q C G E+ C G + G D+NEC +C G SC N +
Sbjct: 52 GGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 110
Query: 221 RC----ICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTC----VCPEGTRH 271
RC C GY D C+DIDEC+ C C+NT GSF C C G
Sbjct: 111 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 170
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR-CINTHGGFEC 330
+ L C DI+EC +++PC G CINT G + C
Sbjct: 171 DA-LGNCIDINEC-------------------------LSISAPCPIGHTCINTEGSYTC 204
Query: 331 E-----CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
+ C GY L+ RC+D VD +C A C S G
Sbjct: 205 QKNVPNCGRGYHLNEEGTRCVD----------VD-ECAPPAEPCGKGHRCVNSPG----- 248
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G +++ C DV+EC G C NT GSY C C G L
Sbjct: 249 -SFRCECKTGYYFDGISRM----CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLS 303
Query: 446 STG 448
G
Sbjct: 304 VDG 306
Score = 50.4 bits (115), Expect = 1e-05
Identities = 58/216 (26%), Positives = 80/216 (37%), Gaps = 23/216 (10%)
Query: 249 CAGG-----QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP 303
C GG QCR+T C C G + + C D++EC T +H +
Sbjct: 50 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECI--TGSHSCRLGESCINTV 107
Query: 304 PTFPTRTELASPCDNGRCINTHGGFEC--ECELGY---VLDATAQRCLDNRRGSCWRRVV 358
+F R + S C G + + ECE G + D Q L + R +
Sbjct: 108 GSF--RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 165
Query: 359 DGQCEAAAPELLLRQECC-----CSVGLAWGSXXXXXXXXXXXXXKG---FAKLDGATCR 410
G + A + EC C +G + G +G C
Sbjct: 166 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 225
Query: 411 DVDECALSAELCAGG-TCVNTDGSYRCDCPPGLTLD 445
DVDECA AE C G CVN+ GS+RC+C G D
Sbjct: 226 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 261
Score = 48.4 bits (110), Expect = 5e-05
Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 2 TNGGMCTNGICKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAG 59
T G +C+ C NI G F+C C GY G C+D+DEC C C N G
Sbjct: 359 TGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 417
Query: 60 SYTCL---CEPGFAPTAAGYC 77
+ CL C + +AA C
Sbjct: 418 GFRCLAFECPENYRRSAATRC 438
Score = 40.3 bits (90), Expect = 0.014
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 6/56 (10%)
Query: 400 GFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC-----DCPPGLTLDSTGT 449
GF + C D++EC ++SA G TC+NT+GSY C +C G L+ GT
Sbjct: 167 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 222
Score = 36.7 bits (81), Expect = 0.17
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCP 439
+G C+D+DEC C+ TC N G +RC +CP
Sbjct: 389 NGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 427
>AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D
precursor protein.
Length = 703
Score = 163 bits (396), Expect = 1e-39
Identities = 113/313 (36%), Positives = 143/313 (45%), Gaps = 33/313 (10%)
Query: 1 MTNGGMCTNG-ICKNIDGGFEC----ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-C 54
+T C G C N G F C C GYE + + C+D+DEC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFIC 279
Query: 55 RNTAGSYTCL----CEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCV---- 104
+NT GS+ C C+ GF A G C D++EC + S C G C+N+EGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 105 -CEAGYRPTATRGACVDVDECEEQ-RVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLG 161
C GY CVDVDEC C G RC N+PGSFRCEC G+ R C+
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 162 LKLGWGVSCQACPAQGSEL---YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ + C + Y C G G DINEC++ P C C N
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECAN 456
Query: 216 LEPGYRCICDPGYH-PDADGL-CRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPE-GTRH 271
+ Y+C C GY D DG+ C DIDEC + + +C N GSF C CP G R
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRL 516
Query: 272 EPELQLCRDIDEC 284
P + C+DIDEC
Sbjct: 517 APNGRNCQDIDEC 529
Score = 142 bits (344), Expect = 2e-33
Identities = 121/377 (32%), Positives = 159/377 (42%), Gaps = 67/377 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
GG C C++ C C GY+ S+G C DV+EC CR G C NT GS+
Sbjct: 183 GGPCKQQ-CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 63 C----LCEPGFAPTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQC----VCEAGYRPT 112
C C G+ T C D+DEC + + C N+ GSF+C C++G+
Sbjct: 242 CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 113 ATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRCE-----CLPGFTLSNDGRTCLGL--- 162
A G C+D++EC C G C NT GS+ C+ C G+ L+ +G C+ +
Sbjct: 302 AL-GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 360
Query: 163 -----KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPG-ACPHGSC 213
G G C P GS + C G D D+NEC PG C H C
Sbjct: 361 APPAEPCGKGHRCVNSP--GS--FRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 214 ENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR-H 271
EN Y C C G+ DG C DI+EC S C+ +C N GS+ C C G +
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLS 472
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ + C DIDEC PT + S RCIN G F+C
Sbjct: 473 DVDGVTCEDIDEC--------------------ALPTGGHICS----YRCINIPGSFQCS 508
Query: 332 C-ELGYVLDATAQRCLD 347
C GY L + C D
Sbjct: 509 CPSSGYRLAPNGRNCQD 525
Score = 107 bits (256), Expect = 1e-22
Identities = 101/362 (27%), Positives = 145/362 (40%), Gaps = 73/362 (20%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSE 179
D C C+ +C +T C C G+ L +DG +C + + SC+ + +
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 180 LYAVLCPEGPS--------KDNGGADINEC-TAVPGACPHGSCENLEPGYRCI----CDP 226
+ + C S +DN DI+EC + + P C+N +RC C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 227 GYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCV-----CPEGTRHEPELQLCRD 280
G+ DA G C DI+EC + C G C NT GS+TC C G E C D
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD 356
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLD 339
+DEC PP A PC G RC+N+ G F CEC+ GY D
Sbjct: 357 VDECA-----------------PP--------AEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 340 ATAQRCLDNRRGSCWR---RVVDGQCE----------AAAPELLLRQECC-----CSVGL 381
++ C+D C R R+ +CE + L + C CS
Sbjct: 392 GISRMCVDVNE--CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP 449
Query: 382 AWGSXXXXXXXXXXXXXKGF--AKLDGATCRDVDECAL--SAELCAGGTCVNTDGSYRCD 437
+G+ + +DG TC D+DECAL +C+ C+N GS++C
Sbjct: 450 CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCS 508
Query: 438 CP 439
CP
Sbjct: 509 CP 510
Score = 97.5 bits (232), Expect = 9e-20
Identities = 54/149 (36%), Positives = 73/149 (48%), Gaps = 13/149 (8%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G +C + C+N G + C C G+ +G C D++EC +P C + C N GSY C
Sbjct: 408 GRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECANVYGSYQC 463
Query: 64 LCEPGF--APTAAGYCADVDECAADS---MCKGGRCVNSEGSFQCVC-EAGYRPTATRGA 117
C G+ + C D+DECA + +C RC+N GSFQC C +GYR
Sbjct: 464 YCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPNGRN 522
Query: 118 CVDVDECEE--QRVCRNGRCHNTPGSFRC 144
C D+DEC N C N G+FRC
Sbjct: 523 CQDIDECVTGIHNCSINETCFNIQGAFRC 551
Score = 70.9 bits (166), Expect = 8e-12
Identities = 87/303 (28%), Positives = 109/303 (35%), Gaps = 67/303 (22%)
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHG-SCENLEPGY 220
G G Q C G E+ C G + G D+NEC +C G SC N +
Sbjct: 182 GGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 221 RC----ICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTC----VCPEGTRH 271
RC C GY D C+DIDEC+ C C+NT GSF C C G
Sbjct: 241 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR-CINTHGGFEC 330
+ L C DI+EC +++PC G CINT G + C
Sbjct: 301 DA-LGNCIDINEC-------------------------LSISAPCPIGHTCINTEGSYTC 334
Query: 331 E-----CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
+ C GY L+ RC+D VD +C A C S G
Sbjct: 335 QKNVPNCGRGYHLNEEGTRCVD----------VD-ECAPPAEPCGKGHRCVNSPG----- 378
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G +++ C DV+EC G C NT GSY C C G L
Sbjct: 379 -SFRCECKTGYYFDGISRM----CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLS 433
Query: 446 STG 448
G
Sbjct: 434 VDG 436
Score = 50.4 bits (115), Expect = 1e-05
Identities = 58/216 (26%), Positives = 80/216 (37%), Gaps = 23/216 (10%)
Query: 249 CAGG-----QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP 303
C GG QCR+T C C G + + C D++EC T +H +
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECI--TGSHSCRLGESCINTV 237
Query: 304 PTFPTRTELASPCDNGRCINTHGGFEC--ECELGY---VLDATAQRCLDNRRGSCWRRVV 358
+F R + S C G + + ECE G + D Q L + R +
Sbjct: 238 GSF--RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 359 DGQCEAAAPELLLRQECC-----CSVGLAWGSXXXXXXXXXXXXXKG---FAKLDGATCR 410
G + A + EC C +G + G +G C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 411 DVDECALSAELCAGG-TCVNTDGSYRCDCPPGLTLD 445
DVDECA AE C G CVN+ GS+RC+C G D
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Query: 2 TNGGMCTNGICKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAG 59
T G +C+ C NI G F+C C GY G C+D+DEC C C N G
Sbjct: 489 TGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 60 SYTCL---CEPGFAPTAA 74
++ CL C + +AA
Sbjct: 548 AFRCLAFECPENYRRSAA 565
Score = 40.3 bits (90), Expect = 0.014
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 6/56 (10%)
Query: 400 GFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC-----DCPPGLTLDSTGT 449
GF + C D++EC ++SA G TC+NT+GSY C +C G L+ GT
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Score = 37.1 bits (82), Expect = 0.13
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 4/39 (10%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCP 439
+G C+D+DEC C+ TC N G++RC +CP
Sbjct: 519 NGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECP 557
>BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein.
Length = 683
Score = 163 bits (395), Expect = 2e-39
Identities = 113/313 (36%), Positives = 142/313 (45%), Gaps = 33/313 (10%)
Query: 1 MTNGGMCTNG-ICKNIDGGFEC----ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-C 54
+T C G C N G F C C GYE + + C+D+DEC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFIC 279
Query: 55 RNTAGSYTCL----CEPGFAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCV---- 104
+NT GS+ C C+ GF A G C D++EC + S C G C+N+EGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 105 -CEAGYRPTATRGACVDVDECEEQ-RVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLG 161
C GY CVDVDEC C G RC N+PGSFRCEC G+ R C+
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 162 LKLGWGVSCQACPAQGSEL---YAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCEN 215
+ + C + Y C G G DINEC++ P C C N
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECAN 456
Query: 216 LEPGYRCICDPGYH-PDADGL-CRDIDECDMHQS-YCAGGQCRNTAGSFTCVCPE-GTRH 271
+ Y+C C GY D DG+ C DIDEC + + +C N GSF C CP G R
Sbjct: 457 VYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRL 516
Query: 272 EPELQLCRDIDEC 284
P C+DIDEC
Sbjct: 517 APNGSNCQDIDEC 529
Score = 142 bits (343), Expect = 3e-33
Identities = 121/377 (32%), Positives = 158/377 (41%), Gaps = 67/377 (17%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
GG C C++ C C GY+ S+G C DV+EC CR G C NT GS+
Sbjct: 183 GGPCKQQ-CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 63 C----LCEPGFAPTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQC----VCEAGYRPT 112
C C G+ T C D+DEC + + C N+ GSF+C C++G+
Sbjct: 242 CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 113 ATRGACVDVDEC-EEQRVCRNGR-CHNTPGSFRCE-----CLPGFTLSNDGRTCLGL--- 162
A G C+D++EC C G C NT GS+ C+ C G+ L+ +G C+ +
Sbjct: 302 AL-GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 360
Query: 163 -----KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPG-ACPHGSC 213
G G C P GS + C G D D+NEC PG C H C
Sbjct: 361 APPAEPCGKGHRCVNSP--GS--FRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 214 ENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR-H 271
EN Y C C G+ DG C DI+EC S C+ +C N GS+ C C G +
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLS 472
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ + C DIDEC PT + S RCIN G F+C
Sbjct: 473 DVDGVTCEDIDEC--------------------ALPTGGHICS----YRCINIPGSFQCS 508
Query: 332 C-ELGYVLDATAQRCLD 347
C GY L C D
Sbjct: 509 CPSSGYRLAPNGSNCQD 525
Score = 116 bits (279), Expect = 2e-25
Identities = 80/249 (32%), Positives = 114/249 (45%), Gaps = 29/249 (11%)
Query: 12 CKNIDGGFECI-----CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLC 65
C N +G + C C GY EG C DVDEC C +G RC N+ GS+ C C
Sbjct: 325 CINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 384
Query: 66 EPGFA-PTAAGYCADVDECAA--DSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+ G+ + C DV+EC +C G +C N+ GS+ C C G+R + +C D++
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLC-GHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN 443
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN-DGRTC-----LGLKLGWGVSCQAC-PA 175
EC + C N GS++C C G+ LS+ DG TC L G + C
Sbjct: 444 ECSSSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINI 501
Query: 176 QGSELYAVLCPEGPSK--DNGG--ADINEC-TAVPGACPHGSCENLEPGYRCI---CDPG 227
GS + CP + NG DI+EC T + + +C N++ G+RC+ C
Sbjct: 502 PGS--FQCSCPSSGYRLAPNGSNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPEN 559
Query: 228 YHPDADGLC 236
Y A C
Sbjct: 560 YRRSAATRC 568
Score = 109 bits (263), Expect = 1e-23
Identities = 74/220 (33%), Positives = 100/220 (45%), Gaps = 35/220 (15%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNP-RVCRRGRCRNTAGSYTCLCEPGFA 70
C N G F C CK GY +C DV+EC+ P R+C +C NT GSY C C GF
Sbjct: 373 CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFR 431
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDECEEQ- 127
+ G C D++EC++ S C C N GS+QC C GY+ + G C D+DEC
Sbjct: 432 LSVDGRSCEDINECSS-SPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 489
Query: 128 --RVCRNGRCHNTPGSFRCEC-LPGFTLSNDG-------------------RTCLGLKLG 165
+C + RC N PGSF+C C G+ L+ +G TC ++ G
Sbjct: 490 GGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGSNCQDIDECVTGIHNCSINETCFNIQGG 548
Query: 166 WGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVP 205
+ CP A C P +N EC+ +P
Sbjct: 549 FRCLAFECPENYRRSAATRCERLPCHEN-----RECSKLP 583
Score = 107 bits (256), Expect = 1e-22
Identities = 101/362 (27%), Positives = 145/362 (40%), Gaps = 73/362 (20%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSE 179
D C C+ +C +T C C G+ L +DG +C + + SC+ + +
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 180 LYAVLCPEGPS--------KDNGGADINEC-TAVPGACPHGSCENLEPGYRCI----CDP 226
+ + C S +DN DI+EC + + P C+N +RC C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 227 GYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCV-----CPEGTRHEPELQLCRD 280
G+ DA G C DI+EC + C G C NT GS+TC C G E C D
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD 356
Query: 281 IDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLD 339
+DEC PP A PC G RC+N+ G F CEC+ GY D
Sbjct: 357 VDECA-----------------PP--------AEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 340 ATAQRCLDNRRGSCWR---RVVDGQCE----------AAAPELLLRQECC-----CSVGL 381
++ C+D C R R+ +CE + L + C CS
Sbjct: 392 GISRMCVDVNE--CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP 449
Query: 382 AWGSXXXXXXXXXXXXXKGF--AKLDGATCRDVDECAL--SAELCAGGTCVNTDGSYRCD 437
+G+ + +DG TC D+DECAL +C+ C+N GS++C
Sbjct: 450 CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCS 508
Query: 438 CP 439
CP
Sbjct: 509 CP 510
Score = 70.9 bits (166), Expect = 8e-12
Identities = 87/303 (28%), Positives = 109/303 (35%), Gaps = 67/303 (22%)
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGA---DINECTAVPGACPHG-SCENLEPGY 220
G G Q C G E+ C G + G D+NEC +C G SC N +
Sbjct: 182 GGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 240
Query: 221 RC----ICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTC----VCPEGTRH 271
RC C GY D C+DIDEC+ C C+NT GSF C C G
Sbjct: 241 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGR-CINTHGGFEC 330
+ L C DI+EC +++PC G CINT G + C
Sbjct: 301 DA-LGNCIDINEC-------------------------LSISAPCPIGHTCINTEGSYTC 334
Query: 331 E-----CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
+ C GY L+ RC+D VD +C A C S G
Sbjct: 335 QKNVPNCGRGYHLNEEGTRCVD----------VD-ECAPPAEPCGKGHRCVNSPG----- 378
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G +++ C DV+EC G C NT GSY C C G L
Sbjct: 379 -SFRCECKTGYYFDGISRM----CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLS 433
Query: 446 STG 448
G
Sbjct: 434 VDG 436
Score = 50.4 bits (115), Expect = 1e-05
Identities = 58/216 (26%), Positives = 80/216 (37%), Gaps = 23/216 (10%)
Query: 249 CAGG-----QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP 303
C GG QCR+T C C G + + C D++EC T +H +
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECI--TGSHSCRLGESCINTV 237
Query: 304 PTFPTRTELASPCDNGRCINTHGGFEC--ECELGY---VLDATAQRCLDNRRGSCWRRVV 358
+F R + S C G + + ECE G + D Q L + R +
Sbjct: 238 GSF--RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 359 DGQCEAAAPELLLRQECC-----CSVGLAWGSXXXXXXXXXXXXXKG---FAKLDGATCR 410
G + A + EC C +G + G +G C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 411 DVDECALSAELCAGG-TCVNTDGSYRCDCPPGLTLD 445
DVDECA AE C G CVN+ GS+RC+C G D
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 49.2 bits (112), Expect = 3e-05
Identities = 28/81 (34%), Positives = 37/81 (45%), Gaps = 6/81 (7%)
Query: 2 TNGGMCTNGICKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAG 59
T G +C+ C NI G F+C C GY G+ C+D+DEC C C N G
Sbjct: 489 TGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGSNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 60 SYTCL---CEPGFAPTAAGYC 77
+ CL C + +AA C
Sbjct: 548 GFRCLAFECPENYRRSAATRC 568
Score = 40.3 bits (90), Expect = 0.014
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 6/56 (10%)
Query: 400 GFAKLDGATCRDVDEC-ALSAELCAGGTCVNTDGSYRC-----DCPPGLTLDSTGT 449
GF + C D++EC ++SA G TC+NT+GSY C +C G L+ GT
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Score = 37.5 bits (83), Expect = 0.097
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 4/39 (10%)
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCP 439
+G+ C+D+DEC C+ TC N G +RC +CP
Sbjct: 519 NGSNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 557
>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 159 bits (386), Expect = 2e-38
Identities = 137/463 (29%), Positives = 185/463 (39%), Gaps = 49/463 (10%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + G+EC C G+E G LC R+VD+C +P C GRC + S++C
Sbjct: 516 CRNGAKCVDQPDGYECRCAEGFE----GTLCDRNVDDCSPDP--CHHGRCVDGIASFSCA 569
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C PG+ T + VDEC + GG+C++ + C C +G T V++D+C
Sbjct: 570 CAPGYTGTRCE--SQVDECRSQPCRHGGKCLDLVDKYLCRCPSG---TTGVNCEVNIDDC 624
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFT--LSN-DGRTCLGLKLGWGVSCQACPAQGSELY 181
C G C + + C C PGFT L N + C G G SC G +
Sbjct: 625 -ASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSC----VDGENGF 679
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDE 241
LCP G + C P C HG C + G+RC+C+PG+ D
Sbjct: 680 RCLCPPGSLPPLCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDA 737
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTR-HEPEL------QLCRDIDECEGETETHYIE 294
C+ Q AGG C + F C CP G + + EL C CE +
Sbjct: 738 CE-SQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVC 796
Query: 295 SDYERGDIPPTFPTRTELA--SPC-DNGRCINTHGGFECECELGYV---LDATAQRCLDN 348
S + P E A +PC +G C N G F C C GY D C N
Sbjct: 797 SCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPN 856
Query: 349 ---RRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GSC V C A P + C S G+ G+
Sbjct: 857 PCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGY 916
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G C +D+ +C+ S+ GGTCV+ S+ C C PG T
Sbjct: 917 G---GFHCEQDLPDCSPSS-CFNGGTCVDGVNSFSCLCRPGYT 955
Score = 132 bits (319), Expect = 2e-30
Identities = 132/467 (28%), Positives = 183/467 (39%), Gaps = 85/467 (18%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCR-NTAGSYT 62
G+C + + F C C G+ G C D C +P C G RC G +
Sbjct: 91 GVCQSSVVAGT-ARFSCRCPRGFR----GPDCSLPDPCLSSP--CAHGARCSVGPDGRFL 143
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C PG+ + +DVDEC C+ GG C+N+ GSF+C C AGY V
Sbjct: 144 CSCPPGYQGRSCR--SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP- 200
Query: 122 DECEEQRVCRNGRCHNTPG--SFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQ 176
C CRNG G ++ C CLPGF N + C G + G +C
Sbjct: 201 --CAPSP-CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTC----VD 253
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGL 235
G Y CP + D++EC P AC +G +C N G+ C+C G+ +
Sbjct: 254 GVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW--TGESC 311
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET--ETHYI 293
++ID+C + G C + SF C CP G LC D C E
Sbjct: 312 SQNIDDCATAVCF-HGATCHDRVASFYCACPMGKTG----LLCHLDDACVSNPCHEDAIC 366
Query: 294 ESDYERG----DIPPTFPTRT------EL---ASPCDN-GRCINTHGGFECECELGYVLD 339
+++ G PP F E A+PC++ GRC+NT G F C+C GY
Sbjct: 367 DTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY--- 423
Query: 340 ATAQRCLDNRRGSCWRRVVDGQC--EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
T RC + C + G C +A + + + C C G
Sbjct: 424 -TGPRC-ETDVNEC----LSGPCRNQATCLDRIGQFTCICMAGFT--------------- 462
Query: 398 XKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G C D+DEC S+ GG C + + C CP G +
Sbjct: 463 --------GTYCEVDIDECQ-SSPCVNGGVCKDRVNGFSCTCPSGFS 500
Score = 131 bits (316), Expect = 6e-30
Identities = 133/458 (29%), Positives = 181/458 (39%), Gaps = 61/458 (13%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLC 65
C++GIC + GGF C+C+PG+ SG + D C P CR G C + + C C
Sbjct: 704 CSHGICYDAPGGFRCVCEPGW-SGPRCSQSLARDACESQP--CRAGGTCSSDGMGFHCTC 760
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQ-CVCEAGYRPTATRGACVDVDEC 124
PG C + C + GGRC ++ G C C G++ + DVDEC
Sbjct: 761 PPG---VQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQ---DVDEC 814
Query: 125 EEQRVCR-NGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C +G C N GSF C C G+T D C G SCQ G
Sbjct: 815 AGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ----DGVGS 870
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
++ C G + D++EC + P C G+C + + C C PGY G + D
Sbjct: 871 FSCSCLPGFAGPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGY----GGFHCEQD 924
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCPEG-----TRHEPELQLCRDIDECEGETETHY-I 293
D S C GG C + SF+C+C G +HE + L R + H
Sbjct: 925 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGF 984
Query: 294 ESDYERGDIPPTFPTRTELAS--PCDNG-RCINTHGGFECECELGYVLDATAQRCLDNRR 350
P T + S PC NG RC+ T G C C G+ + R D R
Sbjct: 985 RCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT--GAYCLCPPGW-----SGRLCDIR- 1036
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC- 409
C AA ++ +R E C G G +G G+ C
Sbjct: 1037 --------SLPCREAAAQIGVRLEQLCQAG---GQCVDEDSSHYCVCPEGRT---GSHCE 1082
Query: 410 RDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDS 446
++VD C A+ C GGTC G Y C+C PG D+
Sbjct: 1083 QEVDPCL--AQPCQHGGTCRGYMGGYMCECLPGYNGDN 1118
Score = 125 bits (302), Expect = 3e-28
Identities = 126/455 (27%), Positives = 176/455 (38%), Gaps = 57/455 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNT--AGS 60
NGG CT + C+C PG+ G C+ D C P RG C+++ AG+
Sbjct: 51 NGGRCTQLPSREA----ACLCPPGWV----GERCQLEDPCHSGP-CAGRGVCQSSVVAGT 101
Query: 61 --YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRC-VNSEGSFQCVCEAGYRPTATRGA 117
++C C GF C+ D C + G RC V +G F C C GY+ + R
Sbjct: 102 ARFSCRCPRGFRGPD---CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS- 157
Query: 118 CVDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQAC 173
DVDEC CR+ G C NTPGSFRC+C G+T N C G +C+
Sbjct: 158 --DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCR-- 213
Query: 174 PAQGSELYAVLCPEGPSKDNGGADINECTAVPG-ACPH-GSCENLEPGYRCICDPGYHPD 231
G Y C G N ++++C PG C + G+C + Y C C P +
Sbjct: 214 -QSGDLTYDCACLPGFEGQNCEVNVDDC---PGHRCLNGGTCVDGVNTYNCQCPPEW--T 267
Query: 232 ADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
D+DEC + + C GG C NT G +CVC G E ++ID+C
Sbjct: 268 GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGE---SCSQNIDDCATAVCF 324
Query: 291 HYIESDYERGDIPPTFPT-RTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
H P +T L D+ C++ + C+ V C
Sbjct: 325 HGATCHDRVASFYCACPMGKTGLLCHLDDA-CVSNPCHEDAICDTNPVNGRAICTCPPGF 383
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
G G C+ E + C +G +G+ G C
Sbjct: 384 TG--------GACDQDVDECSIGANPCEHLGRC----VNTQGSFLCQCGRGYT---GPRC 428
Query: 410 R-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
DV+EC LS TC++ G + C C G T
Sbjct: 429 ETDVNEC-LSGPCRNQATCLDRIGQFTCICMAGFT 462
Score = 123 bits (296), Expect = 1e-27
Identities = 137/469 (29%), Positives = 182/469 (38%), Gaps = 89/469 (18%)
Query: 10 GICKNIDGGFE-CICKPGYESGSEGALCR-DVDECRDNPRVCR-RGRCRNTAGSYTCLCE 66
G C++ G C C G++ G C+ DVDEC P C G C N AGS++C C
Sbjct: 784 GRCESAPGQLPVCSCPQGWQ----GPRCQQDVDECA-GPAPCGPHGICTNLAGSFSCTCH 838
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR-PTATRGACVDVDECE 125
G+ T D+++C + GG C + GSF C C G+ P R DVDEC
Sbjct: 839 GGY--TGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR----DVDECL 892
Query: 126 EQRVCRNGRCHNTPGSFRCECLPG---FTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
C G C + SF C C PG F D C G +C G ++
Sbjct: 893 SNP-CGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTC----VDGVNSFS 947
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYH-PDADGLCRDID 240
LC G + + + + C + P C HG C PG+RC C + P L +D
Sbjct: 948 CLCRPGYTGAHCQHEADPCLSRP--CLHGGVCSAAHPGFRCTCLESFTGPQCQTL---VD 1002
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEG-------TRHEP----------EL-QLCRDID 282
C Q GG+C T G++ C+CP G R P L QLC+
Sbjct: 1003 WCS-RQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG 1059
Query: 283 ECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLDAT 341
+C E +HY R LA PC +G C GG+ CEC GY
Sbjct: 1060 QCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY----N 1115
Query: 342 AQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
C D+ C + Q + +L+ R C C G
Sbjct: 1116 GDNCEDD-VDECASQPC--QHGGSCIDLVARYLCSCPPGTL------------------- 1153
Query: 402 AKLDGATCR-DVDECALSAELCAG------GTCVNTDGSYRCDCPPGLT 443
G C + D+C L +G GTCV+ G +RC CPPG T
Sbjct: 1154 ----GVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT 1198
Score = 123 bits (296), Expect = 1e-27
Identities = 118/389 (30%), Positives = 153/389 (39%), Gaps = 72/389 (18%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSY 61
NGG C +G+ G F C C PG+ G C RDVDEC NP C G C + S+
Sbjct: 860 NGGSCQDGV-----GSFSCSCLPGFA----GPRCARDVDECLSNP--CGPGTCTDHVASF 908
Query: 62 TCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV- 119
TC C PG+ +C D+ +C+ S GG CV+ SF C+C GY T C
Sbjct: 909 TCTCPPGYG---GFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY----TGAHCQH 961
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
+ D C + G C FRC CL FT G C L + W S Q C G
Sbjct: 962 EADPCLSRPCLHGGVCSAAHPGFRCTCLESFT----GPQCQTL-VDW-CSRQPCQNGGRC 1015
Query: 180 LYA---VLCPEGPSK---DNGGADINECTAVPGA-----C-PHGSCENLEPGYRCICDPG 227
+ LCP G S D E A G C G C + + + C+C G
Sbjct: 1016 VQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG 1075
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDECEG 286
+++D C + Q GG CR G + C C G + C D+DEC
Sbjct: 1076 --RTGSHCEQEVDPC-LAQPCQHGGTCRGYMGGYMCECLPGYNGDN----CEDDVDECAS 1128
Query: 287 ETETH-----YIESDYERGDIPPTFPTRTEL-------ASPCD-------NGRCINTHGG 327
+ H + + Y P T E+ P D NG C++ GG
Sbjct: 1129 QPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGG 1188
Query: 328 FECECELGYV---LDATAQRCLDNRRGSC 353
F C C GY +A C R G+C
Sbjct: 1189 FRCTCPPGYTGLRCEADINEC---RSGAC 1214
Score = 122 bits (294), Expect = 3e-27
Identities = 132/470 (28%), Positives = 188/470 (40%), Gaps = 60/470 (12%)
Query: 6 MCTNGI-CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA---GSY 61
+C +G C + F C C G G LC D C NP C +T G
Sbjct: 322 VCFHGATCHDRVASFYCACP----MGKTGLLCHLDDACVSNP--CHEDAICDTNPVNGRA 375
Query: 62 TCLCEPGFAPTAAGYC-ADVDECAADSM-CKG-GRCVNSEGSFQCVCEAGYRPTATRGAC 118
C C PGF G C DVDEC+ + C+ GRCVN++GSF C C GY T R
Sbjct: 376 ICTCPPGFT---GGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY--TGPR-CE 429
Query: 119 VDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACP 174
DV+EC CRN C + G F C C+ GFT D C G C+
Sbjct: 430 TDVNEC-LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKD-R 487
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDAD 233
G ++ CP G S D++EC + P C +G+ C + GY C C G+
Sbjct: 488 VNG---FSCTCPSGFSGSTCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGFE---G 539
Query: 234 GLC-RDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPEL-----QLCRDIDEC 284
LC R++D+C C G+C + SF+C C GTR E ++ Q CR +C
Sbjct: 540 TLCDRNVDDCS--PDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKC 597
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGY---VLDAT 341
+ + + ++PC G C + ++C C+ G+ + +
Sbjct: 598 LDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVE 657
Query: 342 AQRCLDN---RRGSCWRRVVDGQC---EAAAPELLL-RQECCCSVGLAWGSXXXXXXXXX 394
C + GSC +C + P L L C + G
Sbjct: 658 INECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFR 717
Query: 395 XXXXKGFAKLDGATC-RDVDECALSAELC-AGGTCVNTDGSYRCDCPPGL 442
G++ G C + + A ++ C AGGTC + + C CPPG+
Sbjct: 718 CVCEPGWS---GPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 764
Score = 82.6 bits (195), Expect = 3e-15
Identities = 80/283 (28%), Positives = 105/283 (37%), Gaps = 47/283 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTCLCEP 67
G C + D C+C G G+ C ++VD C P C+ G CR G Y C C P
Sbjct: 1059 GQCVDEDSSHYCVCP----EGRTGSHCEQEVDPCLAQP--CQHGGTCRGYMGGYMCECLP 1112
Query: 68 GFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV--DEC 124
G+ C D VDECA+ GG C++ + C C P T G ++ D+C
Sbjct: 1113 GYN---GDNCEDDVDECASQPCQHGGSCIDLVARYLCSC-----PPGTLGVLCEINEDDC 1164
Query: 125 -------EEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCL--GLKLGWGVSCQA 172
R NG C + G FRC C PG+T D C C
Sbjct: 1165 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQ 1224
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG------YRCIC-D 225
P G + LC G S ++ C + P C HG PG + C C
Sbjct: 1225 DPGGG---FRCLCHAGFSGPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQ 1279
Query: 226 PGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
P + P + + R E G C+ T C CP G
Sbjct: 1280 PFWGPRCERVARSCRELQCP----VGVPCQQTPRGPRCACPPG 1318
Score = 66.9 bits (156), Expect = 1e-10
Identities = 53/165 (32%), Positives = 70/165 (42%), Gaps = 19/165 (11%)
Query: 111 PTATRGACVDVDECEEQRVCRNGRCHNTPG-SFRCECLPGFTLSN---DGRTCLGLKLGW 166
P A C+D C GRC P C C PG+ + G G
Sbjct: 36 PGAAAPPCLDGSPC-----ANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGR 90
Query: 167 GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR--CIC 224
GV CQ+ G+ ++ CP G + + C + P C HG+ ++ P R C C
Sbjct: 91 GV-CQSSVVAGTARFSCRCPRGFRGPDCSLP-DPCLSSP--CAHGARCSVGPDGRFLCSC 146
Query: 225 DPGYHPDADGLCR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
PGY + CR D+DEC + + GG C NT GSF C CP G
Sbjct: 147 PPGYQGRS---CRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAG 188
Score = 66.1 bits (154), Expect = 2e-10
Identities = 68/243 (27%), Positives = 96/243 (39%), Gaps = 32/243 (13%)
Query: 1 MTNGGMCT-NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-C-RN 56
+ +G C NG C ++ GGF C C PGY G C D++ECR R C ++
Sbjct: 1170 LDSGPRCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQD 1225
Query: 57 TAGSYTCLCEPGFAPTAAGYCADV-DECAADSMCKGGRCVNSEG-----SFQCVC-EAGY 109
G + CLC GF + C V C + GG+C S G +F C C + +
Sbjct: 1226 PGGGFRCLCHAGF---SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW 1282
Query: 110 RPTATRGA--CVDVDECEE----QRVCRNGRCHNTPG--SFRCECLPGFTLSNDGRTCLG 161
P R A C ++ +C Q+ R RC PG C PG +C
Sbjct: 1283 GPRCERVARSCREL-QCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAA 1341
Query: 162 LKLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGGADINECTAVPGACPHGSCENLEPG 219
G SC+ PA + + C +G + A E + P CP +C+
Sbjct: 1342 APCLHGGSCR--PAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEP-RCPRAACQAKRGD 1398
Query: 220 YRC 222
RC
Sbjct: 1399 QRC 1401
Score = 62.1 bits (144), Expect = 4e-09
Identities = 73/255 (28%), Positives = 100/255 (39%), Gaps = 39/255 (15%)
Query: 222 CICDPGYHPDADGLCRDIDECDMHQSYCAG-GQCRNT--AGS--FTCVCPEGTRHEPELQ 276
C+C PG+ + C+ D C H CAG G C+++ AG+ F+C CP G R P+
Sbjct: 65 CLCPPGWVGER---CQLEDPC--HSGPCAGRGVCQSSVVAGTARFSCRCPRGFRG-PD-- 116
Query: 277 LCRDIDECEGETETHYIESDYERG-----DIPPTFPTRT--------ELASPCDNG-RCI 322
C D C H PP + R+ + PC +G C+
Sbjct: 117 -CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCL 175
Query: 323 NTHGGFECECELGY---VLDATAQRCLDN--RRGSCWRRVVDGQCEAAAPELLLRQECCC 377
NT G F C+C GY + + A C + R G R+ D + A Q C
Sbjct: 176 NTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEV 235
Query: 378 SVGLAWG----SXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALSAELCA-GGTCVNTD 431
+V G + + + G C DVDEC L C GGTC NT
Sbjct: 236 NVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTL 295
Query: 432 GSYRCDCPPGLTLDS 446
G + C C G T +S
Sbjct: 296 GGHSCVCVNGWTGES 310
>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 159 bits (386), Expect = 2e-38
Identities = 137/463 (29%), Positives = 185/463 (39%), Gaps = 49/463 (10%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + G+EC C G+E G LC R+VD+C +P C GRC + S++C
Sbjct: 516 CRNGAKCVDQPDGYECRCAEGFE----GTLCDRNVDDCSPDP--CHHGRCVDGIASFSCA 569
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C PG+ T + VDEC + GG+C++ + C C +G T V++D+C
Sbjct: 570 CAPGYTGTRCE--SQVDECRSQPCRHGGKCLDLVDKYLCRCPSG---TTGVNCEVNIDDC 624
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFT--LSN-DGRTCLGLKLGWGVSCQACPAQGSELY 181
C G C + + C C PGFT L N + C G G SC G +
Sbjct: 625 -ASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSC----VDGENGF 679
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDE 241
LCP G + C P C HG C + G+RC+C+PG+ D
Sbjct: 680 RCLCPPGSLPPLCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDA 737
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTR-HEPEL------QLCRDIDECEGETETHYIE 294
C+ Q AGG C + F C CP G + + EL C CE +
Sbjct: 738 CE-SQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVC 796
Query: 295 SDYERGDIPPTFPTRTELA--SPC-DNGRCINTHGGFECECELGYV---LDATAQRCLDN 348
S + P E A +PC +G C N G F C C GY D C N
Sbjct: 797 SCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPN 856
Query: 349 ---RRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GSC V C A P + C S G+ G+
Sbjct: 857 PCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGY 916
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G C +D+ +C+ S+ GGTCV+ S+ C C PG T
Sbjct: 917 G---GFHCEQDLPDCSPSS-CFNGGTCVDGVNSFSCLCRPGYT 955
Score = 132 bits (319), Expect = 2e-30
Identities = 132/467 (28%), Positives = 183/467 (39%), Gaps = 85/467 (18%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCR-NTAGSYT 62
G+C + + F C C G+ G C D C +P C G RC G +
Sbjct: 91 GVCQSSVVAGT-ARFSCRCPRGFR----GPDCSLPDPCLSSP--CAHGARCSVGPDGRFL 143
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C PG+ + +DVDEC C+ GG C+N+ GSF+C C AGY V
Sbjct: 144 CSCPPGYQGRSCR--SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP- 200
Query: 122 DECEEQRVCRNGRCHNTPG--SFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQ 176
C CRNG G ++ C CLPGF N + C G + G +C
Sbjct: 201 --CAPSP-CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTC----VD 253
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGL 235
G Y CP + D++EC P AC +G +C N G+ C+C G+ +
Sbjct: 254 GVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW--TGESC 311
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET--ETHYI 293
++ID+C + G C + SF C CP G LC D C E
Sbjct: 312 SQNIDDCATAVCF-HGATCHDRVASFYCACPMGKTG----LLCHLDDACVSNPCHEDAIC 366
Query: 294 ESDYERG----DIPPTFPTRT------EL---ASPCDN-GRCINTHGGFECECELGYVLD 339
+++ G PP F E A+PC++ GRC+NT G F C+C GY
Sbjct: 367 DTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY--- 423
Query: 340 ATAQRCLDNRRGSCWRRVVDGQC--EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
T RC + C + G C +A + + + C C G
Sbjct: 424 -TGPRC-ETDVNEC----LSGPCRNQATCLDRIGQFTCICMAGFT--------------- 462
Query: 398 XKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G C D+DEC S+ GG C + + C CP G +
Sbjct: 463 --------GTYCEVDIDECQ-SSPCVNGGVCKDRVNGFSCTCPSGFS 500
Score = 131 bits (316), Expect = 6e-30
Identities = 133/458 (29%), Positives = 181/458 (39%), Gaps = 61/458 (13%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLC 65
C++GIC + GGF C+C+PG+ SG + D C P CR G C + + C C
Sbjct: 704 CSHGICYDAPGGFRCVCEPGW-SGPRCSQSLARDACESQP--CRAGGTCSSDGMGFHCTC 760
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQ-CVCEAGYRPTATRGACVDVDEC 124
PG C + C + GGRC ++ G C C G++ + DVDEC
Sbjct: 761 PPG---VQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQ---DVDEC 814
Query: 125 EEQRVCR-NGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C +G C N GSF C C G+T D C G SCQ G
Sbjct: 815 AGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ----DGVGS 870
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
++ C G + D++EC + P C G+C + + C C PGY G + D
Sbjct: 871 FSCSCLPGFAGPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGY----GGFHCEQD 924
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCPEG-----TRHEPELQLCRDIDECEGETETHY-I 293
D S C GG C + SF+C+C G +HE + L R + H
Sbjct: 925 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGF 984
Query: 294 ESDYERGDIPPTFPTRTELAS--PCDNG-RCINTHGGFECECELGYVLDATAQRCLDNRR 350
P T + S PC NG RC+ T G C C G+ + R D R
Sbjct: 985 RCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT--GAYCLCPPGW-----SGRLCDIR- 1036
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC- 409
C AA ++ +R E C G G +G G+ C
Sbjct: 1037 --------SLPCREAAAQIGVRLEQLCQAG---GQCVDEDSSHYCVCPEGRT---GSHCE 1082
Query: 410 RDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDS 446
++VD C A+ C GGTC G Y C+C PG D+
Sbjct: 1083 QEVDPCL--AQPCQHGGTCRGYMGGYMCECLPGYNGDN 1118
Score = 125 bits (302), Expect = 3e-28
Identities = 126/455 (27%), Positives = 176/455 (38%), Gaps = 57/455 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNT--AGS 60
NGG CT + C+C PG+ G C+ D C P RG C+++ AG+
Sbjct: 51 NGGRCTQLPSREA----ACLCPPGWV----GERCQLEDPCHSGP-CAGRGVCQSSVVAGT 101
Query: 61 --YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRC-VNSEGSFQCVCEAGYRPTATRGA 117
++C C GF C+ D C + G RC V +G F C C GY+ + R
Sbjct: 102 ARFSCRCPRGFRGPD---CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS- 157
Query: 118 CVDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQAC 173
DVDEC CR+ G C NTPGSFRC+C G+T N C G +C+
Sbjct: 158 --DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCR-- 213
Query: 174 PAQGSELYAVLCPEGPSKDNGGADINECTAVPG-ACPH-GSCENLEPGYRCICDPGYHPD 231
G Y C G N ++++C PG C + G+C + Y C C P +
Sbjct: 214 -QSGDLTYDCACLPGFEGQNCEVNVDDC---PGHRCLNGGTCVDGVNTYNCQCPPEW--T 267
Query: 232 ADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
D+DEC + + C GG C NT G +CVC G E ++ID+C
Sbjct: 268 GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGE---SCSQNIDDCATAVCF 324
Query: 291 HYIESDYERGDIPPTFPT-RTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
H P +T L D+ C++ + C+ V C
Sbjct: 325 HGATCHDRVASFYCACPMGKTGLLCHLDDA-CVSNPCHEDAICDTNPVNGRAICTCPPGF 383
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
G G C+ E + C +G +G+ G C
Sbjct: 384 TG--------GACDQDVDECSIGANPCEHLGRC----VNTQGSFLCQCGRGYT---GPRC 428
Query: 410 R-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
DV+EC LS TC++ G + C C G T
Sbjct: 429 ETDVNEC-LSGPCRNQATCLDRIGQFTCICMAGFT 462
Score = 123 bits (296), Expect = 1e-27
Identities = 137/469 (29%), Positives = 182/469 (38%), Gaps = 89/469 (18%)
Query: 10 GICKNIDGGFE-CICKPGYESGSEGALCR-DVDECRDNPRVCR-RGRCRNTAGSYTCLCE 66
G C++ G C C G++ G C+ DVDEC P C G C N AGS++C C
Sbjct: 784 GRCESAPGQLPVCSCPQGWQ----GPRCQQDVDECA-GPAPCGPHGICTNLAGSFSCTCH 838
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR-PTATRGACVDVDECE 125
G+ T D+++C + GG C + GSF C C G+ P R DVDEC
Sbjct: 839 GGY--TGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR----DVDECL 892
Query: 126 EQRVCRNGRCHNTPGSFRCECLPG---FTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
C G C + SF C C PG F D C G +C G ++
Sbjct: 893 SNP-CGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTC----VDGVNSFS 947
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYH-PDADGLCRDID 240
LC G + + + + C + P C HG C PG+RC C + P L +D
Sbjct: 948 CLCRPGYTGAHCQHEADPCLSRP--CLHGGVCSAAHPGFRCTCLESFTGPQCQTL---VD 1002
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEG-------TRHEP----------EL-QLCRDID 282
C Q GG+C T G++ C+CP G R P L QLC+
Sbjct: 1003 WCS-RQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG 1059
Query: 283 ECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLDAT 341
+C E +HY R LA PC +G C GG+ CEC GY
Sbjct: 1060 QCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY----N 1115
Query: 342 AQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
C D+ C + Q + +L+ R C C G
Sbjct: 1116 GDNCEDD-VDECASQPC--QHGGSCIDLVARYLCSCPPGTL------------------- 1153
Query: 402 AKLDGATCR-DVDECALSAELCAG------GTCVNTDGSYRCDCPPGLT 443
G C + D+C L +G GTCV+ G +RC CPPG T
Sbjct: 1154 ----GVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT 1198
Score = 123 bits (296), Expect = 1e-27
Identities = 118/389 (30%), Positives = 153/389 (39%), Gaps = 72/389 (18%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSY 61
NGG C +G+ G F C C PG+ G C RDVDEC NP C G C + S+
Sbjct: 860 NGGSCQDGV-----GSFSCSCLPGFA----GPRCARDVDECLSNP--CGPGTCTDHVASF 908
Query: 62 TCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV- 119
TC C PG+ +C D+ +C+ S GG CV+ SF C+C GY T C
Sbjct: 909 TCTCPPGYG---GFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY----TGAHCQH 961
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
+ D C + G C FRC CL FT G C L + W S Q C G
Sbjct: 962 EADPCLSRPCLHGGVCSAAHPGFRCTCLESFT----GPQCQTL-VDW-CSRQPCQNGGRC 1015
Query: 180 LYA---VLCPEGPSK---DNGGADINECTAVPGA-----C-PHGSCENLEPGYRCICDPG 227
+ LCP G S D E A G C G C + + + C+C G
Sbjct: 1016 VQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG 1075
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDECEG 286
+++D C + Q GG CR G + C C G + C D+DEC
Sbjct: 1076 --RTGSHCEQEVDPC-LAQPCQHGGTCRGYMGGYMCECLPGYNGDN----CEDDVDECAS 1128
Query: 287 ETETH-----YIESDYERGDIPPTFPTRTEL-------ASPCD-------NGRCINTHGG 327
+ H + + Y P T E+ P D NG C++ GG
Sbjct: 1129 QPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGG 1188
Query: 328 FECECELGYV---LDATAQRCLDNRRGSC 353
F C C GY +A C R G+C
Sbjct: 1189 FRCTCPPGYTGLRCEADINEC---RSGAC 1214
Score = 122 bits (294), Expect = 3e-27
Identities = 132/470 (28%), Positives = 188/470 (40%), Gaps = 60/470 (12%)
Query: 6 MCTNGI-CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA---GSY 61
+C +G C + F C C G G LC D C NP C +T G
Sbjct: 322 VCFHGATCHDRVASFYCACP----MGKTGLLCHLDDACVSNP--CHEDAICDTNPVNGRA 375
Query: 62 TCLCEPGFAPTAAGYC-ADVDECAADSM-CKG-GRCVNSEGSFQCVCEAGYRPTATRGAC 118
C C PGF G C DVDEC+ + C+ GRCVN++GSF C C GY T R
Sbjct: 376 ICTCPPGFT---GGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY--TGPR-CE 429
Query: 119 VDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACP 174
DV+EC CRN C + G F C C+ GFT D C G C+
Sbjct: 430 TDVNEC-LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKD-R 487
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDAD 233
G ++ CP G S D++EC + P C +G+ C + GY C C G+
Sbjct: 488 VNG---FSCTCPSGFSGSTCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGFE---G 539
Query: 234 GLC-RDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPEL-----QLCRDIDEC 284
LC R++D+C C G+C + SF+C C GTR E ++ Q CR +C
Sbjct: 540 TLCDRNVDDCS--PDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKC 597
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGY---VLDAT 341
+ + + ++PC G C + ++C C+ G+ + +
Sbjct: 598 LDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVE 657
Query: 342 AQRCLDN---RRGSCWRRVVDGQC---EAAAPELLL-RQECCCSVGLAWGSXXXXXXXXX 394
C + GSC +C + P L L C + G
Sbjct: 658 INECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFR 717
Query: 395 XXXXKGFAKLDGATC-RDVDECALSAELC-AGGTCVNTDGSYRCDCPPGL 442
G++ G C + + A ++ C AGGTC + + C CPPG+
Sbjct: 718 CVCEPGWS---GPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 764
Score = 82.6 bits (195), Expect = 3e-15
Identities = 80/283 (28%), Positives = 105/283 (37%), Gaps = 47/283 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTCLCEP 67
G C + D C+C G G+ C ++VD C P C+ G CR G Y C C P
Sbjct: 1059 GQCVDEDSSHYCVCP----EGRTGSHCEQEVDPCLAQP--CQHGGTCRGYMGGYMCECLP 1112
Query: 68 GFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV--DEC 124
G+ C D VDECA+ GG C++ + C C P T G ++ D+C
Sbjct: 1113 GYN---GDNCEDDVDECASQPCQHGGSCIDLVARYLCSC-----PPGTLGVLCEINEDDC 1164
Query: 125 -------EEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCL--GLKLGWGVSCQA 172
R NG C + G FRC C PG+T D C C
Sbjct: 1165 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQ 1224
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG------YRCIC-D 225
P G + LC G S ++ C + P C HG PG + C C
Sbjct: 1225 DPGGG---FRCLCHAGFSGPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQ 1279
Query: 226 PGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
P + P + + R E G C+ T C CP G
Sbjct: 1280 PFWGPRCERVARSCRELQCP----VGVPCQQTPRGPRCACPPG 1318
Score = 66.9 bits (156), Expect = 1e-10
Identities = 53/165 (32%), Positives = 70/165 (42%), Gaps = 19/165 (11%)
Query: 111 PTATRGACVDVDECEEQRVCRNGRCHNTPG-SFRCECLPGFTLSN---DGRTCLGLKLGW 166
P A C+D C GRC P C C PG+ + G G
Sbjct: 36 PGAAAPPCLDGSPC-----ANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGR 90
Query: 167 GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR--CIC 224
GV CQ+ G+ ++ CP G + + C + P C HG+ ++ P R C C
Sbjct: 91 GV-CQSSVVAGTARFSCRCPRGFRGPDCSLP-DPCLSSP--CAHGARCSVGPDGRFLCSC 146
Query: 225 DPGYHPDADGLCR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
PGY + CR D+DEC + + GG C NT GSF C CP G
Sbjct: 147 PPGYQGRS---CRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAG 188
Score = 66.1 bits (154), Expect = 2e-10
Identities = 68/243 (27%), Positives = 96/243 (39%), Gaps = 32/243 (13%)
Query: 1 MTNGGMCT-NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-C-RN 56
+ +G C NG C ++ GGF C C PGY G C D++ECR R C ++
Sbjct: 1170 LDSGPRCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQD 1225
Query: 57 TAGSYTCLCEPGFAPTAAGYCADV-DECAADSMCKGGRCVNSEG-----SFQCVC-EAGY 109
G + CLC GF + C V C + GG+C S G +F C C + +
Sbjct: 1226 PGGGFRCLCHAGF---SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW 1282
Query: 110 RPTATRGA--CVDVDECEE----QRVCRNGRCHNTPG--SFRCECLPGFTLSNDGRTCLG 161
P R A C ++ +C Q+ R RC PG C PG +C
Sbjct: 1283 GPRCERVARSCREL-QCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAA 1341
Query: 162 LKLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGGADINECTAVPGACPHGSCENLEPG 219
G SC+ PA + + C +G + A E + P CP +C+
Sbjct: 1342 APCLHGGSCR--PAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEP-RCPRAACQAKRGD 1398
Query: 220 YRC 222
RC
Sbjct: 1399 QRC 1401
Score = 62.1 bits (144), Expect = 4e-09
Identities = 73/255 (28%), Positives = 100/255 (39%), Gaps = 39/255 (15%)
Query: 222 CICDPGYHPDADGLCRDIDECDMHQSYCAG-GQCRNT--AGS--FTCVCPEGTRHEPELQ 276
C+C PG+ + C+ D C H CAG G C+++ AG+ F+C CP G R P+
Sbjct: 65 CLCPPGWVGER---CQLEDPC--HSGPCAGRGVCQSSVVAGTARFSCRCPRGFRG-PD-- 116
Query: 277 LCRDIDECEGETETHYIESDYERG-----DIPPTFPTRT--------ELASPCDNG-RCI 322
C D C H PP + R+ + PC +G C+
Sbjct: 117 -CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCL 175
Query: 323 NTHGGFECECELGY---VLDATAQRCLDN--RRGSCWRRVVDGQCEAAAPELLLRQECCC 377
NT G F C+C GY + + A C + R G R+ D + A Q C
Sbjct: 176 NTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEV 235
Query: 378 SVGLAWG----SXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALSAELCA-GGTCVNTD 431
+V G + + + G C DVDEC L C GGTC NT
Sbjct: 236 NVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTL 295
Query: 432 GSYRCDCPPGLTLDS 446
G + C C G T +S
Sbjct: 296 GGHSCVCVNGWTGES 310
>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
Length = 2281
Score = 159 bits (386), Expect = 2e-38
Identities = 137/463 (29%), Positives = 185/463 (39%), Gaps = 49/463 (10%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + G+EC C G+E G LC R+VD+C +P C GRC + S++C
Sbjct: 476 CRNGAKCVDQPDGYECRCAEGFE----GTLCDRNVDDCSPDP--CHHGRCVDGIASFSCA 529
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C PG+ T + VDEC + GG+C++ + C C +G T V++D+C
Sbjct: 530 CAPGYTGTRCE--SQVDECRSQPCRHGGKCLDLVDKYLCRCPSG---TTGVNCEVNIDDC 584
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFT--LSN-DGRTCLGLKLGWGVSCQACPAQGSELY 181
C G C + + C C PGFT L N + C G G SC G +
Sbjct: 585 -ASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSC----VDGENGF 639
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDE 241
LCP G + C P C HG C + G+RC+C+PG+ D
Sbjct: 640 RCLCPPGSLPPLCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDA 697
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTR-HEPEL------QLCRDIDECEGETETHYIE 294
C+ Q AGG C + F C CP G + + EL C CE +
Sbjct: 698 CE-SQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVC 756
Query: 295 SDYERGDIPPTFPTRTELA--SPC-DNGRCINTHGGFECECELGYV---LDATAQRCLDN 348
S + P E A +PC +G C N G F C C GY D C N
Sbjct: 757 SCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPN 816
Query: 349 ---RRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GSC V C A P + C S G+ G+
Sbjct: 817 PCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGY 876
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G C +D+ +C+ S+ GGTCV+ S+ C C PG T
Sbjct: 877 G---GFHCEQDLPDCSPSS-CFNGGTCVDGVNSFSCLCRPGYT 915
Score = 132 bits (319), Expect = 2e-30
Identities = 132/467 (28%), Positives = 183/467 (39%), Gaps = 85/467 (18%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCR-NTAGSYT 62
G+C + + F C C G+ G C D C +P C G RC G +
Sbjct: 51 GVCQSSVVAGT-ARFSCRCPRGFR----GPDCSLPDPCLSSP--CAHGARCSVGPDGRFL 103
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C PG+ + +DVDEC C+ GG C+N+ GSF+C C AGY V
Sbjct: 104 CSCPPGYQGRSCR--SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP- 160
Query: 122 DECEEQRVCRNGRCHNTPG--SFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQ 176
C CRNG G ++ C CLPGF N + C G + G +C
Sbjct: 161 --CAPSP-CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTC----VD 213
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGL 235
G Y CP + D++EC P AC +G +C N G+ C+C G+ +
Sbjct: 214 GVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW--TGESC 271
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET--ETHYI 293
++ID+C + G C + SF C CP G LC D C E
Sbjct: 272 SQNIDDCATAVCF-HGATCHDRVASFYCACPMGKTG----LLCHLDDACVSNPCHEDAIC 326
Query: 294 ESDYERG----DIPPTFPTRT------EL---ASPCDN-GRCINTHGGFECECELGYVLD 339
+++ G PP F E A+PC++ GRC+NT G F C+C GY
Sbjct: 327 DTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY--- 383
Query: 340 ATAQRCLDNRRGSCWRRVVDGQC--EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
T RC + C + G C +A + + + C C G
Sbjct: 384 -TGPRC-ETDVNEC----LSGPCRNQATCLDRIGQFTCICMAGFT--------------- 422
Query: 398 XKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G C D+DEC S+ GG C + + C CP G +
Sbjct: 423 --------GTYCEVDIDECQ-SSPCVNGGVCKDRVNGFSCTCPSGFS 460
Score = 131 bits (316), Expect = 6e-30
Identities = 133/458 (29%), Positives = 181/458 (39%), Gaps = 61/458 (13%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLC 65
C++GIC + GGF C+C+PG+ SG + D C P CR G C + + C C
Sbjct: 664 CSHGICYDAPGGFRCVCEPGW-SGPRCSQSLARDACESQP--CRAGGTCSSDGMGFHCTC 720
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQ-CVCEAGYRPTATRGACVDVDEC 124
PG C + C + GGRC ++ G C C G++ + DVDEC
Sbjct: 721 PPG---VQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQ---DVDEC 774
Query: 125 EEQRVCR-NGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C +G C N GSF C C G+T D C G SCQ G
Sbjct: 775 AGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ----DGVGS 830
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
++ C G + D++EC + P C G+C + + C C PGY G + D
Sbjct: 831 FSCSCLPGFAGPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGY----GGFHCEQD 884
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCPEG-----TRHEPELQLCRDIDECEGETETHY-I 293
D S C GG C + SF+C+C G +HE + L R + H
Sbjct: 885 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGF 944
Query: 294 ESDYERGDIPPTFPTRTELAS--PCDNG-RCINTHGGFECECELGYVLDATAQRCLDNRR 350
P T + S PC NG RC+ T G C C G+ + R D R
Sbjct: 945 RCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT--GAYCLCPPGW-----SGRLCDIR- 996
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC- 409
C AA ++ +R E C G G +G G+ C
Sbjct: 997 --------SLPCREAAAQIGVRLEQLCQAG---GQCVDEDSSHYCVCPEGRT---GSHCE 1042
Query: 410 RDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDS 446
++VD C A+ C GGTC G Y C+C PG D+
Sbjct: 1043 QEVDPCL--AQPCQHGGTCRGYMGGYMCECLPGYNGDN 1078
Score = 125 bits (302), Expect = 3e-28
Identities = 126/455 (27%), Positives = 176/455 (38%), Gaps = 57/455 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNT--AGS 60
NGG CT + C+C PG+ G C+ D C P RG C+++ AG+
Sbjct: 11 NGGRCTQLPSREA----ACLCPPGWV----GERCQLEDPCHSGP-CAGRGVCQSSVVAGT 61
Query: 61 --YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRC-VNSEGSFQCVCEAGYRPTATRGA 117
++C C GF C+ D C + G RC V +G F C C GY+ + R
Sbjct: 62 ARFSCRCPRGFRGPD---CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS- 117
Query: 118 CVDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQAC 173
DVDEC CR+ G C NTPGSFRC+C G+T N C G +C+
Sbjct: 118 --DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCR-- 173
Query: 174 PAQGSELYAVLCPEGPSKDNGGADINECTAVPG-ACPH-GSCENLEPGYRCICDPGYHPD 231
G Y C G N ++++C PG C + G+C + Y C C P +
Sbjct: 174 -QSGDLTYDCACLPGFEGQNCEVNVDDC---PGHRCLNGGTCVDGVNTYNCQCPPEW--T 227
Query: 232 ADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
D+DEC + + C GG C NT G +CVC G E ++ID+C
Sbjct: 228 GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGE---SCSQNIDDCATAVCF 284
Query: 291 HYIESDYERGDIPPTFPT-RTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
H P +T L D+ C++ + C+ V C
Sbjct: 285 HGATCHDRVASFYCACPMGKTGLLCHLDDA-CVSNPCHEDAICDTNPVNGRAICTCPPGF 343
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
G G C+ E + C +G +G+ G C
Sbjct: 344 TG--------GACDQDVDECSIGANPCEHLGRC----VNTQGSFLCQCGRGYT---GPRC 388
Query: 410 R-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
DV+EC LS TC++ G + C C G T
Sbjct: 389 ETDVNEC-LSGPCRNQATCLDRIGQFTCICMAGFT 422
Score = 123 bits (296), Expect = 1e-27
Identities = 137/469 (29%), Positives = 182/469 (38%), Gaps = 89/469 (18%)
Query: 10 GICKNIDGGFE-CICKPGYESGSEGALCR-DVDECRDNPRVCR-RGRCRNTAGSYTCLCE 66
G C++ G C C G++ G C+ DVDEC P C G C N AGS++C C
Sbjct: 744 GRCESAPGQLPVCSCPQGWQ----GPRCQQDVDECA-GPAPCGPHGICTNLAGSFSCTCH 798
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR-PTATRGACVDVDECE 125
G+ T D+++C + GG C + GSF C C G+ P R DVDEC
Sbjct: 799 GGY--TGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR----DVDECL 852
Query: 126 EQRVCRNGRCHNTPGSFRCECLPG---FTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
C G C + SF C C PG F D C G +C G ++
Sbjct: 853 SNP-CGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTC----VDGVNSFS 907
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYH-PDADGLCRDID 240
LC G + + + + C + P C HG C PG+RC C + P L +D
Sbjct: 908 CLCRPGYTGAHCQHEADPCLSRP--CLHGGVCSAAHPGFRCTCLESFTGPQCQTL---VD 962
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEG-------TRHEP----------EL-QLCRDID 282
C Q GG+C T G++ C+CP G R P L QLC+
Sbjct: 963 WCS-RQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG 1019
Query: 283 ECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLDAT 341
+C E +HY R LA PC +G C GG+ CEC GY
Sbjct: 1020 QCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY----N 1075
Query: 342 AQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
C D+ C + Q + +L+ R C C G
Sbjct: 1076 GDNCEDD-VDECASQPC--QHGGSCIDLVARYLCSCPPGTL------------------- 1113
Query: 402 AKLDGATCR-DVDECALSAELCAG------GTCVNTDGSYRCDCPPGLT 443
G C + D+C L +G GTCV+ G +RC CPPG T
Sbjct: 1114 ----GVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT 1158
Score = 123 bits (296), Expect = 1e-27
Identities = 118/389 (30%), Positives = 153/389 (39%), Gaps = 72/389 (18%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSY 61
NGG C +G+ G F C C PG+ G C RDVDEC NP C G C + S+
Sbjct: 820 NGGSCQDGV-----GSFSCSCLPGFA----GPRCARDVDECLSNP--CGPGTCTDHVASF 868
Query: 62 TCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV- 119
TC C PG+ +C D+ +C+ S GG CV+ SF C+C GY T C
Sbjct: 869 TCTCPPGYG---GFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY----TGAHCQH 921
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
+ D C + G C FRC CL FT G C L + W S Q C G
Sbjct: 922 EADPCLSRPCLHGGVCSAAHPGFRCTCLESFT----GPQCQTL-VDW-CSRQPCQNGGRC 975
Query: 180 LYA---VLCPEGPSK---DNGGADINECTAVPGA-----C-PHGSCENLEPGYRCICDPG 227
+ LCP G S D E A G C G C + + + C+C G
Sbjct: 976 VQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG 1035
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDECEG 286
+++D C + Q GG CR G + C C G + C D+DEC
Sbjct: 1036 --RTGSHCEQEVDPC-LAQPCQHGGTCRGYMGGYMCECLPGYNGDN----CEDDVDECAS 1088
Query: 287 ETETH-----YIESDYERGDIPPTFPTRTEL-------ASPCD-------NGRCINTHGG 327
+ H + + Y P T E+ P D NG C++ GG
Sbjct: 1089 QPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGG 1148
Query: 328 FECECELGYV---LDATAQRCLDNRRGSC 353
F C C GY +A C R G+C
Sbjct: 1149 FRCTCPPGYTGLRCEADINEC---RSGAC 1174
Score = 122 bits (294), Expect = 3e-27
Identities = 132/470 (28%), Positives = 188/470 (40%), Gaps = 60/470 (12%)
Query: 6 MCTNGI-CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA---GSY 61
+C +G C + F C C G G LC D C NP C +T G
Sbjct: 282 VCFHGATCHDRVASFYCACP----MGKTGLLCHLDDACVSNP--CHEDAICDTNPVNGRA 335
Query: 62 TCLCEPGFAPTAAGYC-ADVDECAADSM-CKG-GRCVNSEGSFQCVCEAGYRPTATRGAC 118
C C PGF G C DVDEC+ + C+ GRCVN++GSF C C GY T R
Sbjct: 336 ICTCPPGFT---GGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY--TGPR-CE 389
Query: 119 VDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACP 174
DV+EC CRN C + G F C C+ GFT D C G C+
Sbjct: 390 TDVNEC-LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKD-R 447
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDAD 233
G ++ CP G S D++EC + P C +G+ C + GY C C G+
Sbjct: 448 VNG---FSCTCPSGFSGSTCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGFE---G 499
Query: 234 GLC-RDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPEL-----QLCRDIDEC 284
LC R++D+C C G+C + SF+C C GTR E ++ Q CR +C
Sbjct: 500 TLCDRNVDDCS--PDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKC 557
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGY---VLDAT 341
+ + + ++PC G C + ++C C+ G+ + +
Sbjct: 558 LDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVE 617
Query: 342 AQRCLDN---RRGSCWRRVVDGQC---EAAAPELLL-RQECCCSVGLAWGSXXXXXXXXX 394
C + GSC +C + P L L C + G
Sbjct: 618 INECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFR 677
Query: 395 XXXXKGFAKLDGATC-RDVDECALSAELC-AGGTCVNTDGSYRCDCPPGL 442
G++ G C + + A ++ C AGGTC + + C CPPG+
Sbjct: 678 CVCEPGWS---GPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 724
Score = 82.6 bits (195), Expect = 3e-15
Identities = 80/283 (28%), Positives = 105/283 (37%), Gaps = 47/283 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTCLCEP 67
G C + D C+C G G+ C ++VD C P C+ G CR G Y C C P
Sbjct: 1019 GQCVDEDSSHYCVCP----EGRTGSHCEQEVDPCLAQP--CQHGGTCRGYMGGYMCECLP 1072
Query: 68 GFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV--DEC 124
G+ C D VDECA+ GG C++ + C C P T G ++ D+C
Sbjct: 1073 GYN---GDNCEDDVDECASQPCQHGGSCIDLVARYLCSC-----PPGTLGVLCEINEDDC 1124
Query: 125 -------EEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCL--GLKLGWGVSCQA 172
R NG C + G FRC C PG+T D C C
Sbjct: 1125 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQ 1184
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG------YRCIC-D 225
P G + LC G S ++ C + P C HG PG + C C
Sbjct: 1185 DPGGG---FRCLCHAGFSGPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQ 1239
Query: 226 PGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
P + P + + R E G C+ T C CP G
Sbjct: 1240 PFWGPRCERVARSCRELQCP----VGVPCQQTPRGPRCACPPG 1278
Score = 66.5 bits (155), Expect = 2e-10
Identities = 51/153 (33%), Positives = 68/153 (44%), Gaps = 15/153 (9%)
Query: 124 CEEQRVCRNG-RCHNTPG-SFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGS 178
C + C NG RC P C C PG+ + G G GV CQ+ G+
Sbjct: 3 CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGV-CQSSVVAGT 61
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR--CICDPGYHPDADGLC 236
++ CP G + + C + P C HG+ ++ P R C C PGY + C
Sbjct: 62 ARFSCRCPRGFRGPDCSLP-DPCLSSP--CAHGARCSVGPDGRFLCSCPPGYQGRS---C 115
Query: 237 R-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
R D+DEC + + GG C NT GSF C CP G
Sbjct: 116 RSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAG 148
Score = 66.1 bits (154), Expect = 2e-10
Identities = 68/243 (27%), Positives = 96/243 (39%), Gaps = 32/243 (13%)
Query: 1 MTNGGMCT-NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-C-RN 56
+ +G C NG C ++ GGF C C PGY G C D++ECR R C ++
Sbjct: 1130 LDSGPRCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQD 1185
Query: 57 TAGSYTCLCEPGFAPTAAGYCADV-DECAADSMCKGGRCVNSEG-----SFQCVC-EAGY 109
G + CLC GF + C V C + GG+C S G +F C C + +
Sbjct: 1186 PGGGFRCLCHAGF---SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW 1242
Query: 110 RPTATRGA--CVDVDECEE----QRVCRNGRCHNTPG--SFRCECLPGFTLSNDGRTCLG 161
P R A C ++ +C Q+ R RC PG C PG +C
Sbjct: 1243 GPRCERVARSCREL-QCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAA 1301
Query: 162 LKLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGGADINECTAVPGACPHGSCENLEPG 219
G SC+ PA + + C +G + A E + P CP +C+
Sbjct: 1302 APCLHGGSCR--PAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEP-RCPRAACQAKRGD 1358
Query: 220 YRC 222
RC
Sbjct: 1359 QRC 1361
Score = 62.1 bits (144), Expect = 4e-09
Identities = 73/255 (28%), Positives = 100/255 (39%), Gaps = 39/255 (15%)
Query: 222 CICDPGYHPDADGLCRDIDECDMHQSYCAG-GQCRNT--AGS--FTCVCPEGTRHEPELQ 276
C+C PG+ + C+ D C H CAG G C+++ AG+ F+C CP G R P+
Sbjct: 25 CLCPPGWVGER---CQLEDPC--HSGPCAGRGVCQSSVVAGTARFSCRCPRGFRG-PD-- 76
Query: 277 LCRDIDECEGETETHYIESDYERG-----DIPPTFPTRT--------ELASPCDNG-RCI 322
C D C H PP + R+ + PC +G C+
Sbjct: 77 -CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCL 135
Query: 323 NTHGGFECECELGY---VLDATAQRCLDN--RRGSCWRRVVDGQCEAAAPELLLRQECCC 377
NT G F C+C GY + + A C + R G R+ D + A Q C
Sbjct: 136 NTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEV 195
Query: 378 SVGLAWG----SXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALSAELCA-GGTCVNTD 431
+V G + + + G C DVDEC L C GGTC NT
Sbjct: 196 NVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTL 255
Query: 432 GSYRCDCPPGLTLDS 446
G + C C G T +S
Sbjct: 256 GGHSCVCVNGWTGES 270
>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein
variant protein.
Length = 2067
Score = 158 bits (384), Expect = 3e-38
Identities = 124/433 (28%), Positives = 177/433 (40%), Gaps = 53/433 (12%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNS 97
+ DEC +P + GRC + + C C GF Y DVDECA+ G +C++
Sbjct: 2 NTDECASSPCL-HNGRCLDKINEFQCECPTGFTGHLCQY--DVDECASTPCKNGAKCLDG 58
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSN 154
++ CVC GY T VD+DEC+ C G C + +F C C PG+T
Sbjct: 59 PNTYTCVCTEGYTGTHCE---VDIDECDPD-PCHYGSCKDGVATFTCLCRPGYTGHHCET 114
Query: 155 DGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCE 214
+ C G +CQ Y C +G + N ++++C + P C G+C
Sbjct: 115 NINECSSQPCRHGGTCQ----DRDNAYLCFCLKGTTGPNCEINLDDCASSP--CDSGTCL 168
Query: 215 NLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEP 273
+ GY C C+PGY +C +IDEC + + GG C + FTC CPEG H+P
Sbjct: 169 DKIDGYECACEPGY---TGSMCNINIDECAGNPCH-NGGTCEDGINGFTCRCPEG-YHDP 223
Query: 274 ELQLCRDIDECEGETETHYIESDYERG---DIPPTFP-TRTEL------ASPCDN-GRCI 322
+++EC H D G D P + T ++ ++PC N G C
Sbjct: 224 --TCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCK 281
Query: 323 NTHGGFECECELGYV---LDATAQRCLDN---RRGSCWRRVVDGQCEAAAP------ELL 370
+ G+ C C G+ C N +G+C V +C P E++
Sbjct: 282 DMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVV 341
Query: 371 LRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELCA-GGTCV 428
L C G G TC D++EC LS C G +C
Sbjct: 342 LAP--CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSP--CRHGASCQ 397
Query: 429 NTDGSYRCDCPPG 441
NT G YRC C G
Sbjct: 398 NTHGGYRCHCQAG 410
Score = 132 bits (320), Expect = 2e-30
Identities = 129/461 (27%), Positives = 184/461 (39%), Gaps = 69/461 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + + C C G+ G C + +C ++ G C + S+TCL
Sbjct: 466 CRNGANCTDCVDSYTCTCPAGFS----GIHCENNTPDCTESS-CFNGGTCVDGINSFTCL 520
Query: 65 CEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PGF YC DV+EC + GG C + GS++C C GY T C ++
Sbjct: 521 CPPGFT---GSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY----TGPNCQNLVH 573
Query: 124 CEEQRVCRNG-RCHNTPGSFRCECLPGFT-LSND--GRTCLGLKLGWGVS----CQ---A 172
+ C+NG +C T +RCEC G+T L D +C GV CQ
Sbjct: 574 WCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGL 633
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPD 231
C G+ + C G + ++EC+ P C +G+ C + GY C C GYH
Sbjct: 634 CVDAGNTHHC-RCQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSCKCVAGYH-- 688
Query: 232 ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
+IDEC H GG C + ++ C CP GT+ + ++D+C
Sbjct: 689 GVNCSEEIDECLSHPCQ-NGGTCLDLPNTYKCSCPRGTQG---VHCEINVDDCN------ 738
Query: 292 YIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECECELGYV---LDATAQRCLD 347
PP P + C +NG C++ GG+ C C G+V + CL
Sbjct: 739 -----------PPVDPVSR--SPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLS 785
Query: 348 N---RRG--SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF- 401
N RG +C +RV D CE A R E + +GF
Sbjct: 786 NPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFI 845
Query: 402 ----AKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A +GATC + S GGTC++ S C C
Sbjct: 846 CKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLC 886
Score = 132 bits (319), Expect = 2e-30
Identities = 128/466 (27%), Positives = 186/466 (39%), Gaps = 61/466 (13%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C++ D + C C G+ G C ++D+C +P C G C + Y C CEPG
Sbjct: 128 GTCQDRDNAYLCFCL----KGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPG 181
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR-PTATRGACVDVDECEEQ 127
+ + ++DECA + GG C + F C C GY PT +V+EC
Sbjct: 182 YTGSMCNI--NIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLS----EVNECNSN 235
Query: 128 RVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
C +G C ++ ++C+C PG++ +N + V+ C S Y C E
Sbjct: 236 P-CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSG-YVCTCRE 293
Query: 188 GPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQS 247
G S N +INEC + P G+C + GY+C C Y G ++ S
Sbjct: 294 GFSGPNCQTNINECASNP-CLNQGTCIDDVAGYKCNCLLPY----TGATCEVVLAPCAPS 348
Query: 248 YCA-GGQCRNTAG--SFTCVCPEGTR--------HEPELQLCRDIDECEGETETH--YIE 294
C GG+CR + SF+CVCP G + +E L CR C+ + + +
Sbjct: 349 PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQ 408
Query: 295 SDYE----RGDIPPTFPTRTELASPCDNG------RCINTHGGFECECELGYVLD----- 339
+ Y DI P C +G C+ G CE ++
Sbjct: 409 AGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRN 468
Query: 340 -ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX 398
A C+D+ +C CE P+ E C G G+
Sbjct: 469 GANCTDCVDSYTCTCPAGFSGIHCENNTPDCT---ESSCFNG---GTCVDGINSFTCLCP 522
Query: 399 KGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
GF G+ C+ DV+EC S GGTC + GSYRC CP G T
Sbjct: 523 PGFT---GSYCQHDVNECD-SQPCLHGGTCQDGCGSYRCTCPQGYT 564
Score = 127 bits (306), Expect = 9e-29
Identities = 128/467 (27%), Positives = 180/467 (38%), Gaps = 57/467 (12%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGSYTCL 64
C G CK+ F C+C+PGY G C +++EC P CR G C++ +Y C
Sbjct: 87 CHYGSCKDGVATFTCLCRPGYT----GHHCETNINECSSQP--CRHGGTCQDRDNAYLCF 140
Query: 65 CEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDVD 122
C G T C ++D+CA+ S C G C++ ++C CE GY T C +++D
Sbjct: 141 CLKG---TTGPNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGY----TGSMCNINID 192
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
EC G C + F C C G+ T ++ C G AC
Sbjct: 193 ECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHG----AC-RDSLN 247
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRD 238
Y C G S N + NEC + P C +G +C+++ GY C C G+ +
Sbjct: 248 GYKCDCDPGWSGTNCDINNNECESNP--CVNGGTCKDMTSGYVCTCREGF--SGPNCQTN 303
Query: 239 IDECDMHQSYCAGGQCRNTAG-SFTCVCP-EGTRHEPELQLCRDIDECEGETETHYIESD 296
I+EC + G + AG C+ P G E L C C E E D
Sbjct: 304 INECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP-SPCRNGGECRQSE-D 361
Query: 297 YERGD-IPPT--------FPTRTELASPCDNGR-CINTHGGFECECELGYV---LDATAQ 343
YE + PT + SPC +G C NTHGG+ C C+ GY +
Sbjct: 362 YESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDID 421
Query: 344 RCLDN---RRGSCWRRVVDGQCEA--AAPELLLRQEC--CCSVGLAWGSXXXXXXXXXXX 396
C N GSC + C+ ++ C S G+
Sbjct: 422 DCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTC 481
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
A G C + + GGTCV+ S+ C CPPG T
Sbjct: 482 TCP--AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT 526
Score = 118 bits (285), Expect = 3e-26
Identities = 124/485 (25%), Positives = 191/485 (39%), Gaps = 76/485 (15%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCRDV-DECRDNPRVCRRG-RCRNTAG--SY 61
C N G C + G++C C Y GA C V C +P CR G CR + S+
Sbjct: 312 CLNQGTCIDDVAGYKCNCLLPYT----GATCEVVLAPCAPSP--CRNGGECRQSEDYESF 365
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
+C+C G+ D++EC G C N+ G ++C C+AGY + R D+
Sbjct: 366 SCVCPTGWQGQTCE--VDINECVLSPCRHGASCQNTHGGYRCHCQAGY---SGRNCETDI 420
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
D+C G C + + C+CLPGF D C G +C C
Sbjct: 421 DDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDC----V 476
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
+ Y CP G S + + +CT +C + G+C + + C+C PG+ C+
Sbjct: 477 DSYTCTCPAGFSGIHCENNTPDCT--ESSCFNGGTCVDGINSFTCLCPPGF---TGSYCQ 531
Query: 238 -DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR--------HEPELQLCRDIDECEGET 288
D++ECD Q GG C++ GS+ C CP+G H + C++ +C +T
Sbjct: 532 HDVNECD-SQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC-WQT 589
Query: 289 ETHYIESDYERG------DIPPTF------PTRTELASPCDN-GRCINTHGGFECECELG 335
T Y + G D+P ++A C + G C++ C C+ G
Sbjct: 590 HTQY-RCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAG 648
Query: 336 YV---LDATAQRCLDN--RRGSCWRRVVDG-QCEAAAPELLLR-----QECCCSVGLAWG 384
Y + C + + G+ + G C+ A + EC G
Sbjct: 649 YTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGG 708
Query: 385 SXXXXXXXXXXXXXKGFAKLDGATCR-DVDEC-------ALSAELCAGGTCVNTDGSYRC 436
+ +G G C +VD+C + S + GTCV+ G Y C
Sbjct: 709 TCLDLPNTYKCSCPRG---TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC 765
Query: 437 DCPPG 441
CPPG
Sbjct: 766 TCPPG 770
Score = 115 bits (277), Expect = 3e-25
Identities = 126/477 (26%), Positives = 185/477 (38%), Gaps = 76/477 (15%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGSYTCL 64
C +G C + G+EC C+PGY G++C ++DEC NP C G C + +TC
Sbjct: 162 CDSGTCLDKIDGYECACEPGYT----GSMCNINIDECAGNP--CHNGGTCEDGINGFTCR 215
Query: 65 CEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C G+ PT ++V+EC ++ C G C +S ++C C+ G+ T ++ +E
Sbjct: 216 CPEGYHDPTCL---SEVNECNSNP-CVHGACRDSLNGYKCDCDPGWSGT---NCDINNNE 268
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSN--------------DGRTCLGLKLGWGVS 169
CE G C + + C C GF+ N + TC+ G+ +
Sbjct: 269 CESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 328
Query: 170 CQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
C P G+ VL P PS G EC E+ E + C+C G+
Sbjct: 329 C-LLPYTGATCEVVLAPCAPSPCRNGG---ECR---------QSEDYE-SFSCVCPTGWQ 374
Query: 230 PDADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECE 285
+ DI+EC + S C G C+NT G + C C G E ++ CR
Sbjct: 375 GQTCEV--DINECVL--SPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHN 430
Query: 286 GETETHYIESDYERGDIPPTFPTR------TELAS-PCDNG-RCINTHGGFECECELGYV 337
G + T I + + D P F E AS PC NG C + + C C G+
Sbjct: 431 GGSCTDGINTAF--CDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFS 488
Query: 338 LDATAQRCLDNRRGSCWR--RVVDG------QCEAAAPELLLRQ---ECCCSVGLAWGSX 386
D SC+ VDG C + EC L G+
Sbjct: 489 GIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTC 548
Query: 387 XXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G+ G C+++ S+ GG C T YRC+CP G T
Sbjct: 549 QDGCGSYRCTCPQGYT---GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT 602
Score = 106 bits (255), Expect = 1e-22
Identities = 129/478 (26%), Positives = 175/478 (36%), Gaps = 63/478 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N C +G C++ G++C C PG+ SG+ + + +EC NP V G C++ Y
Sbjct: 233 NSNPCVHGACRDSLNGYKCDCDPGW-SGTNCDI--NNNECESNPCV-NGGTCKDMTSGYV 288
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C GF + +++ECA++ G C++ ++C C Y T C V
Sbjct: 289 CTCREGF--SGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY----TGATCEVVL 342
Query: 123 ECEEQRVCRN-GRCHNTPG--SFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQ 176
CRN G C + SF C C G+ T D C+ G SCQ
Sbjct: 343 APCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQ--NTH 400
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL 235
G Y C G S N DI++C P C + GSC + C C PG+
Sbjct: 401 GG--YRCHCQAGYSGRNCETDIDDCR--PNPCHNGGSCTDGINTAFCDCLPGFR---GTF 453
Query: 236 C-RDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETETH 291
C DI+EC G C + S+TC CP G E C + G T
Sbjct: 454 CEEDINEC-ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD 512
Query: 292 YIESDYERGDIPPTFPTR------TELAS-PC-DNGRCINTHGGFECECELGYV---LDA 340
I S PP F E S PC G C + G + C C GY
Sbjct: 513 GINS--FTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQN 570
Query: 341 TAQRCLDN---RRGSCWRRVVDGQCEAAA---------PEL---LLRQECCCSVGLAWGS 385
C + G CW+ +CE + P + + Q V
Sbjct: 571 LVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQH 630
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRD-VDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
+ A G+ C D VDEC+ S C G TC + G Y C C G
Sbjct: 631 GGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAG 686
Score = 97.5 bits (232), Expect = 9e-20
Identities = 97/367 (26%), Positives = 147/367 (40%), Gaps = 53/367 (14%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSY 61
NGG C +GI F C+C PG+ G+ C+ DV+EC P G C++ GSY
Sbjct: 506 NGGTCVDGI-----NSFTCLCPPGF----TGSYCQHDVNECDSQP-CLHGGTCQDGCGSY 555
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYR------PTAT 114
C C G+ C ++ S CK GG+C + ++C C +G+ P+ +
Sbjct: 556 RCTCPQGY---TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVS 612
Query: 115 RGACVDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQA 172
+ R+C++ G C + + C C G+T G C L S CQ
Sbjct: 613 CEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQN 668
Query: 173 CPAQGSEL--YAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCIC---DP 226
L Y+ C G N +I+EC + P C + G+C +L Y+C C
Sbjct: 669 GATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQ 726
Query: 227 GYHPD--ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDI 281
G H + D +D G C + G ++C CP G R E ++ C
Sbjct: 727 GVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLS- 785
Query: 282 DECEGETETHYIE--SDYERGDIPPTFPTRTE------LASPCDN-GRCI---NTHGGFE 329
+ C+ + ++ +D+ R E PC N G C NT GF
Sbjct: 786 NPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFI 845
Query: 330 CECELGY 336
C+C G+
Sbjct: 846 CKCPAGF 852
Score = 95.1 bits (226), Expect = 5e-19
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 39/344 (11%)
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPA 175
V+ DEC NGRC + F+CEC GFT D C G C
Sbjct: 1 VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKC----L 56
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL 235
G Y +C EG + + DI+EC P C +GSC++ + C+C PGY
Sbjct: 57 DGPNTYTCVCTEGYTGTHCEVDIDECD--PDPCHYGSCKDGVATFTCLCRPGY--TGHHC 112
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT---RHEPELQLCRDIDECEGETETHY 292
+I+EC Q GG C++ ++ C C +GT E L C C+ T
Sbjct: 113 ETNINECS-SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCAS-SPCDSGTCLDK 170
Query: 293 IESDYERGDIPPTFPTRTEL------ASPCDN-GRCINTHGGFECECELGY---VLDATA 342
I+ YE P + + +PC N G C + GF C C GY +
Sbjct: 171 IDG-YECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEV 229
Query: 343 QRCLDNR--RGSCWRRVVDGQCE-----AAAPELLLRQECCCSVGLAWGSXXXXXXXXXX 395
C N G+C + +C+ + + EC + + G+
Sbjct: 230 NECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVC 289
Query: 396 XXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDC 438
+GF+ G C+ +++ECA S GTC++ Y+C+C
Sbjct: 290 TCREGFS---GPNCQTNINECA-SNPCLNQGTCIDDVAGYKCNC 329
Score = 81.8 bits (193), Expect = 5e-15
Identities = 80/286 (27%), Positives = 116/286 (40%), Gaps = 43/286 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRD-------NPRVCRRGRCRNT 57
C NG C ++ ++C C G++G C +VD+C +P+ G C +
Sbjct: 704 CQNGGTCLDLPNTYKCSCP----RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQ 759
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGG--RCVNSEGSFQCVCEAGYRPTATR 115
G Y+C C PGF DV+EC ++ G CV F C C AG+ T R
Sbjct: 760 VGGYSCTCPPGFVGERCE--GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH--TGRR 815
Query: 116 GACVDVDECEEQRVCRNGRC---HNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVS 169
V ++ C+ + G C NT F C+C GF T ND RTC L+ G +
Sbjct: 816 CESV-INGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGT 874
Query: 170 CQACPAQGSELYAVLCP-EGPSKDNGGADINECTAVPGACPHGSCE--NLEPGYRCICDP 226
C + P S L P GP + + C G+CE + P YRC+C
Sbjct: 875 CISGPR--SPTCLCLGPFTGPECQFPAS--SPCLGGNPCYNQGTCEPTSESPFYRCLCPA 930
Query: 227 GY---------HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
+ + G RDI + + C +C+ AG+ C
Sbjct: 931 KFNGLLCHILDYSFGGGAGRDIPP-PLIEEACELPECQEDAGNKVC 975
Score = 79.0 bits (186), Expect = 3e-14
Identities = 75/282 (26%), Positives = 111/282 (39%), Gaps = 36/282 (12%)
Query: 185 CPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR-DIDEC 242
CP G + D++EC + P C +G+ C + Y C+C GY C DIDEC
Sbjct: 28 CPTGFTGHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGY---TGTHCEVDIDEC 82
Query: 243 DMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQL-------CRDIDECEGETETHYIE 294
D C G C++ +FTC+C G T H E + CR C+ + + Y+
Sbjct: 83 DPDP--CHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQ-DRDNAYL- 138
Query: 295 SDYERGDIPPTFPTRTE--LASPCDNGRCINTHGGFECECELGY---VLDATAQRCLDN- 348
+G P + +SPCD+G C++ G+EC CE GY + + C N
Sbjct: 139 CFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNP 198
Query: 349 --RRGSCWRRVVDGQCEAAA----PELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA 402
G+C + C P L C S G+ G++
Sbjct: 199 CHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWS 258
Query: 403 KLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLT 443
G C D++ + C GGTC + Y C C G +
Sbjct: 259 ---GTNC-DINNNECESNPCVNGGTCKDMTSGYVCTCREGFS 296
Score = 31.1 bits (67), Expect = 8.4
Identities = 12/33 (36%), Positives = 19/33 (57%), Gaps = 1/33 (3%)
Query: 411 DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+ DECA S+ G C++ ++C+CP G T
Sbjct: 2 NTDECA-SSPCLHNGRCLDKINEFQCECPTGFT 33
>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 157 bits (380), Expect = 1e-37
Identities = 127/464 (27%), Positives = 186/464 (40%), Gaps = 51/464 (10%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N C + GGF C+C PG++ G C +++EC+ NP V G+C + + CL
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQSNPCV-NNGQCVDKVNRFQCL 519
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD-VDE 123
C PGF T D+D+C++ G +C++ ++C C G+ T C + +D
Sbjct: 520 CPPGF--TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF----TGVLCEENIDN 573
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--- 180
C+ C +G+C + S+ C C PG+ G C ++ S C G +
Sbjct: 574 CDPDP-CHHGQCQDGIDSYTCICNPGYM----GAICSD-QIDECYS-SPCLNDGRCIDLV 626
Query: 181 --YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
Y C G S N + ++C + P C HG C + Y C+C PG+ + D
Sbjct: 627 NGYQCNCQPGTSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGFTGQRCNI--D 682
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEP---ELQLCRDID----ECEGETETH 291
IDEC + G C N F C+CPEG H ++ C C G +
Sbjct: 683 IDECASNPCR-KGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGY 741
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELG---YVLDATAQRCLD 347
D I L++PC NG C N G+ C C+ G Y C
Sbjct: 742 KCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECAS 801
Query: 348 N---RRGSCWRRVVDGQCEAAAPELLLRQECC---CSVGLAWGSXXXXXXXXXXXXXKGF 401
N +G+C+ + C P + CS +
Sbjct: 802 NPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLC 861
Query: 402 AK-LDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
A G C D+DEC +S G C NT GSY C+CPPG +
Sbjct: 862 APGWQGQRCTIDIDEC-ISKPCMNHGLCHNTQGSYMCECPPGFS 904
Score = 144 bits (349), Expect = 6e-34
Identities = 130/470 (27%), Positives = 199/470 (42%), Gaps = 67/470 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + G+EC C G+ G LC + +D C +P C G+C++ SYTC+
Sbjct: 541 CLNGAKCIDHPNGYECQCATGFT----GVLCEENIDNCDPDP--CHHGQCQDGIDSYTCI 594
Query: 65 CEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PG+ C+D +DEC + GRC++ +QC C+ G T+ ++ D+
Sbjct: 595 CNPGY---MGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPG---TSGVNCEINFDD 648
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C C +G C + + C C PGFT + D C G +C G
Sbjct: 649 C-ASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC----INGVNG 703
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
+ +CPEGP + + +NEC + P C HG+C GY+C+CD G+ G+ ++D
Sbjct: 704 FRCICPEGPHHPSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW----VGINCEVD 757
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG----ETETHYIE- 294
+ + + C GG C N + C C +G + Q+ +IDEC T + +
Sbjct: 758 KNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGY-NCQV--NIDECASNPCLNQGTCFDDI 814
Query: 295 SDYERGDIPPTF--PTRTELA----SPCDNGRCINTHGGFE---CECELGY--------V 337
S Y + P +T LA +PC+N FE C C G+ +
Sbjct: 815 SGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
Query: 338 LDATAQRCLD-----NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
+ ++ C++ N +GS G E + +C + GS
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDI--DDCLANPCQNGGSCMDGVNT 932
Query: 393 XXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G C+ D++EC LS GGTC + SY C C G
Sbjct: 933 FSCLCLPGFT---GDKCQTDMNEC-LSEPCKNGGTCSDYVNSYTCKCQAG 978
Score = 140 bits (338), Expect = 1e-32
Identities = 111/385 (28%), Positives = 164/385 (42%), Gaps = 52/385 (13%)
Query: 1 MTNGGMCTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNT 57
M N C + G C N DG F C C GY G C D++EC +P C+ C +
Sbjct: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP--CQNDATCLDK 474
Query: 58 AGSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG 116
G +TCLC PGF +C +++EC ++ G+CV+ FQC+C G+ T
Sbjct: 475 IGGFTCLCMPGFKGV---HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGP 527
Query: 117 AC-VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQA 172
C +D+D+C +C + P + C+C GFT + C G CQ
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQ- 585
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
G + Y +C G I+EC + P G C +L GY+C C PG
Sbjct: 586 ---DGIDSYTCICNPGYMGAICSDQIDECYSSP-CLNDGRCIDLVNGYQCNCQPG----T 637
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDEC------E 285
G+ +I+ D + C G C + ++CVC G Q C DIDEC +
Sbjct: 638 SGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG----QRCNIDIDECASNPCRK 693
Query: 286 GETETHYIESDY----ERGDIPPTFPTRTE-LASPCDNGRCINTHGGFECECELGYV--- 337
G T + + E P + E L++PC +G C G++C C+ G+V
Sbjct: 694 GATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGIN 753
Query: 338 LDATAQRCLDN--RRGSCWRRVVDG 360
+ CL N + G +V+G
Sbjct: 754 CEVDKNECLSNPCQNGGTCDNLVNG 778
Score = 136 bits (330), Expect = 1e-31
Identities = 128/456 (28%), Positives = 182/456 (39%), Gaps = 64/456 (14%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C N+ G+ C CK G++ G C+ ++DEC NP + +G C + YTC
Sbjct: 766 CQNGGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECASNPCL-NQGTCFDDISGYTCH 820
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGR-CVNSEG--SFQCVCEAGYRPTATRGACVDV 121
C P C V + + C+ C S S+ C+C G++ + +D+
Sbjct: 821 C---VLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQG---QRCTIDI 874
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
DEC + +G CHNT GS+ CEC PGF+ D CL G SC G
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCM----DGV 930
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
++ LC G + D D+NEC + P C + G+C + Y C C G+ D
Sbjct: 931 NTFSCLCLPGFTGDKCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF--DGVHCEN 986
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR--------HEPELQLCRDIDECEGETE 289
+I+EC S GG C + SF+C+CP G +E C + C
Sbjct: 987 NINEC-TESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLG 1045
Query: 290 THYIESDYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGYVLDATAQRCL 346
T+ G T L SPC N G C+ +C C G+
Sbjct: 1046 TY--RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW---------- 1093
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
+ V + C+ AA + E C G G+ G
Sbjct: 1094 ----AGAYCDVPNVSCDIAASRRGVLVEHLCQHS---GVCINAGNTHYCQCPLGYT---G 1143
Query: 407 ATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ C + +DECA S G TC + G YRC+C PG
Sbjct: 1144 SYCEEQLDECA-SNPCQHGATCSDFIGGYRCECVPG 1178
Score = 132 bits (319), Expect = 2e-30
Identities = 128/454 (28%), Positives = 182/454 (40%), Gaps = 57/454 (12%)
Query: 15 IDGGFECICKPGYESGSEGALC-RDVDECR-DNPRVCRR-GRCRNTAGSYTCLCEPGFAP 71
++G + C C GY+ GA C DVDEC N C G+C NT G++ C C G+A
Sbjct: 395 LNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
Query: 72 TAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCR 131
D++EC +D C++ G F C+C G++ ++++EC+
Sbjct: 451 PRCEM--DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCE---LEINECQSNPCVN 505
Query: 132 NGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG 188
NG+C + F+C C PGFT D C G C P G Y C G
Sbjct: 506 NGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP-NG---YECQCATG 561
Query: 189 PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD-IDECDMHQS 247
+ +I+ C P C HG C++ Y CIC+PGY +C D IDEC + S
Sbjct: 562 FTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGY---MGAICSDQIDEC--YSS 614
Query: 248 YCAG-GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD----YERGDI 302
C G+C + + C C GT + + D+C H I D Y
Sbjct: 615 PCLNDGRCIDLVNGYQCNCQPGT---SGVNCEINFDDCASNPCIHGICMDGINRYSCVCS 671
Query: 303 PPTFPTRTEL------ASPCDNG-RCINTHGGFECECELG---YVLDATAQRCLDNR--R 350
P R + ++PC G CIN GF C C G + CL N
Sbjct: 672 PGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIH 731
Query: 351 GSCWRRVVDGQCEAAAPELLL-----RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD 405
G+C + +C A + + + EC + G+ KGF
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGF---K 788
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDC 438
G C+ ++DECA S GTC + Y C C
Sbjct: 789 GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC 821
Score = 125 bits (302), Expect = 3e-28
Identities = 132/476 (27%), Positives = 190/476 (39%), Gaps = 74/476 (15%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N G C ++ G++C C+PG + G C + D+C NP C G C + Y+C+
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNP--CIHGICMDGINRYSCV 669
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG-YRPTATRGACVDVDE 123
C PGF T D+DECA++ KG C+N F+C+C G + P+ V+E
Sbjct: 670 CSPGF--TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYS----QVNE 723
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGSEL 180
C C +G C ++C C G+ N D CL G +C G
Sbjct: 724 CLSNP-CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL-VNG--- 778
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
Y C +G N +I+EC + P G+C + GY C C Y
Sbjct: 779 YRCTCKKGFKGYNCQVNIDECASNP-CLNQGTCFDDISGYTCHCVLPYTGK--------- 828
Query: 241 ECDMHQSYCAGGQCRNTA--------GSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C + C+ C N A S+TC+C G + + + DIDEC + ++
Sbjct: 829 NCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ---RCTIDIDECISKPCMNH 885
Query: 293 IESDYERG----DIPPTFPTRTE-------LASPCDNG-RCINTHGGFECECELGYVLD- 339
+G + PP F LA+PC NG C++ F C C G+ D
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDK 945
Query: 340 --ATAQRCLDN---RRGSCWRRVVDGQCEAAAPELLLR-----QECCCSVGLAWGSXXXX 389
CL G+C V C+ A + EC S G+
Sbjct: 946 CQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
Query: 390 XXXXXXXXXKGFAKLDGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPGLT 443
GF G+ C +++EC S+ C GTCV+ G+YRC CP G T
Sbjct: 1006 INSFSCLCPVGFT---GSFCLHEINEC--SSHPCLNEGTCVDGLGTYRCSCPLGYT 1056
Score = 120 bits (290), Expect = 8e-27
Identities = 93/346 (26%), Positives = 137/346 (39%), Gaps = 35/346 (10%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C NG+ GF CIC G S V+EC NP C G C Y C
Sbjct: 694 GATCINGV-----NGFRCICPEGPHHPS---CYSQVNECLSNP--CIHGNCTGGLSGYKC 743
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
LC+ G+ D +EC ++ GG C N ++C C+ G++ + V++DE
Sbjct: 744 LCDAGWVGINCE--VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ---VNIDE 798
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYA 182
C G C + + C C+ +T N + C + E Y
Sbjct: 799 CASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP-DADGLCRDIDE 241
LC G DI+EC + P HG C N + Y C C PG+ D + DID+
Sbjct: 859 CLCAPGWQGQRCTIDIDECISKP-CMNHGLCHNTQGSYMCECPPGFSGMDCE---EDIDD 914
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEGETETHYIES--- 295
C + GG C + +F+C+C P G + + ++ C G T + Y+ S
Sbjct: 915 C-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTC 973
Query: 296 ----DYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGY 336
++ TE S C NG C++ F C C +G+
Sbjct: 974 KCQAGFDGVHCENNINECTE--SSCFNGGTCVDGINSFSCLCPVGF 1017
Score = 116 bits (280), Expect = 1e-25
Identities = 121/457 (26%), Positives = 174/457 (38%), Gaps = 65/457 (14%)
Query: 7 CTNG-ICKNIDG--GFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYT 62
C N +CK + C+C PG++ G C D+DEC P + G C NT GSY
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECISKPCM-NHGLCHNTQGSYM 896
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDV 121
C C PGF+ D+D+C A+ GG C++ +F C+C G+ T C D+
Sbjct: 897 CECPPGFSGMDCE--EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF----TGDKCQTDM 950
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
+EC + G C + S+ C+C GF N+ C G +C G
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTC----VDGI 1006
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
++ LCP G + +INEC++ P G+C + YRC C GY
Sbjct: 1007 NSFSCLCPVGFTGSFCLHEINECSSHP-CLNEGTCVDGLGTYRCSCPLGYTGK------- 1058
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
C + C+ C+N TCV + + E Q C Y +
Sbjct: 1059 --NCQTLVNLCSRSPCKNKG---TCV-----QKKAESQCL-----CPSGWAGAYCDVPNV 1103
Query: 299 RGDIPPTFPTRTELASP-CDN-GRCINTHGGFECECELGYV---LDATAQRCLDN--RRG 351
DI + R L C + G CIN C+C LGY + C N + G
Sbjct: 1104 SCDIAAS--RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHG 1161
Query: 352 SCWRRVVDG-QCEAAAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD 405
+ + G +CE + EC G+ G
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR--- 1218
Query: 406 GATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C + +D+CA GG C++ G Y C C PG
Sbjct: 1219 GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPG 1255
Score = 116 bits (279), Expect = 2e-25
Identities = 121/470 (25%), Positives = 174/470 (37%), Gaps = 60/470 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGS 60
NGG+C +G+ + C C P + G C DVDEC P C+ G C N G
Sbjct: 271 NGGVCVDGV-----NTYNCRCPPQWT----GQFCTEDVDECLLQPNACQNGGTCANRNGG 321
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
Y C+C G++ ++D+CA S G C++ SF C+C P G
Sbjct: 322 YGCVCVNGWSGDDCS--ENIDDCAFASCTPGSTCIDRVASFSCMC-----PEGKAGLLCH 374
Query: 121 VDECEEQRVCRNGR-CHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACP 174
+D+ C G C P G + C C G+ + D C C
Sbjct: 375 LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCV 434
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDAD 233
+ C +G + DINEC + P C + +C + G+ C+C PG+
Sbjct: 435 NTDGAFHCE-CLKGYAGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFKGVHC 491
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
L +I+EC + GQC + F C+CP G P Q+ DID+C +
Sbjct: 492 EL--EINECQSNPC-VNNGQCVDKVNRFQCLCPPGFT-GPVCQI--DIDDCSSTPCLNGA 545
Query: 294 ES-DYERGDIPPTFPTRTEL----------ASPCDNGRCINTHGGFECECELGY---VLD 339
+ D+ G T + PC +G+C + + C C GY +
Sbjct: 546 KCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICS 605
Query: 340 ATAQRCLDN---RRGSCWRRVVDGQCE----AAAPELLLRQECCCSVGLAWGSXXXXXXX 392
C + G C V QC + + + C S G
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINR 665
Query: 393 XXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G C D+DECA S G TC+N +RC CP G
Sbjct: 666 YSCVCSPGFT---GQRCNIDIDECA-SNPCRKGATCINGVNGFRCICPEG 711
Score = 108 bits (260), Expect = 3e-23
Identities = 101/374 (27%), Positives = 151/374 (40%), Gaps = 52/374 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ F C+C PG+ G C+ D++EC P C+ G C + S
Sbjct: 922 NGGSCMDGV-----NTFSCLCLPGFT----GDKCQTDMNECLSEP--CKNGGTCSDYVNS 970
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
YTC C+ GF +C + ++EC S GG CV+ SF C+C G+ T C+
Sbjct: 971 YTCKCQAGFDGV---HCENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCL 1023
Query: 120 -DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+++EC G C + G++RC C G+T N +T + L + Q
Sbjct: 1024 HEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKN-CQTLVNLCSRSPCKNKGTCVQKK 1082
Query: 179 ELYAVLCPEG--------PSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYH 229
LCP G P+ A V C H G C N + C C GY
Sbjct: 1083 AESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY- 1141
Query: 230 PDADGLCRD-IDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECE 285
C + +DEC + G C + G + C C +G E E+ C++ C+
Sbjct: 1142 --TGSYCEEQLDECASNPCQ-HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQN-QPCQ 1197
Query: 286 GETETHYIESDYERGDIPPTFPTRTE------LASP-CDN-GRCINTHGGFECECELGYV 337
+ + ++ P T E P C N G+C++ GG+ C C G+
Sbjct: 1198 NGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA 1257
Query: 338 ---LDATAQRCLDN 348
+ CL N
Sbjct: 1258 GERCEGDINECLSN 1271
Score = 106 bits (255), Expect = 1e-22
Identities = 125/435 (28%), Positives = 162/435 (37%), Gaps = 48/435 (11%)
Query: 41 ECRDNPRVC-RRGRCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSE 98
+CRD C G C G+ C C GF YC D C + GG CV
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFL---GEYCQHRDPCEKNRCQNGGTCVAQA 83
Query: 99 --GSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNG-RCHN-TPGSFRCECLPGFTLSN 154
G C C +G+ T C R C NG CH + ++ C C GFT
Sbjct: 84 MLGKATCRCASGF--TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE 141
Query: 155 DGRT--CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG- 211
T CL G +C Q ++ C G + D+NEC +PG C HG
Sbjct: 142 CQWTDACLSHPCANGSTCTTVANQ----FSCKCLTGFTGQKCETDVNECD-IPGHCQHGG 196
Query: 212 SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAG-SFTCVC-P-- 266
+C NL Y+C C G+ G D S C GG CR T +F C C P
Sbjct: 197 TCLNLPGSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGF 252
Query: 267 EGTRHEPELQ-----LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP--CDNG 319
EG+ E + C++ C T+ + T L P C NG
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNG 312
Query: 320 -RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWR------RVVDGQC---EAAAPEL 369
C N +GG+ C C G+ D ++ D SC RV C E A L
Sbjct: 313 GTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLL 372
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALS-AELCA-GGT 426
+ C S G+ GA C DVDECA++ + C G
Sbjct: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGK 432
Query: 427 CVNTDGSYRCDCPPG 441
CVNTDG++ C+C G
Sbjct: 433 CVNTDGAFHCECLKG 447
Score = 100 bits (240), Expect = 9e-21
Identities = 80/270 (29%), Positives = 112/270 (41%), Gaps = 35/270 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
+G+C N C C GY G+ C + +DEC NP C+ G C + G Y C C
Sbjct: 1123 SGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASNP--CQHGATCSDFIGGYRCECV 1176
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD--VDEC 124
PG+ Y +VDEC GG C++ F+C C P TRG + +D+C
Sbjct: 1177 PGYQGVNCEY--EVDECQNQPCQNGGTCIDLVNHFKCSC-----PPGTRGLLCEENIDDC 1229
Query: 125 EEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C N G+C + G + C CLPGF D CL S Q +
Sbjct: 1230 ARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDC--IQLTND 1287
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSC---ENLEPGYRCICDPGYHPDADGLCR 237
Y +C + + ++ C +P G+C N+ G+ C C PG+ + C+
Sbjct: 1288 YLCVCRSAFTGRHCETFVDVCPQMP-CLNGGTCAVASNMPDGFICRCPPGF---SGARCQ 1343
Query: 238 DIDECDMHQSYC-AGGQCRNTAGSFTCVCP 266
C Q C G QC +TA C CP
Sbjct: 1344 --SSCG--QVKCRKGEQCVHTASGPRCFCP 1369
Score = 93.5 bits (222), Expect = 1e-18
Identities = 68/232 (29%), Positives = 97/232 (41%), Gaps = 31/232 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C ++ F+C C PG + G LC + +D+C P G+C + G Y+C
Sbjct: 1196 CQNGGTCIDLVNHFKCSCPPG----TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCR 1251
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGR--CVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C PGFA D++EC ++ G C+ + CVC + + R VD
Sbjct: 1252 CLPGFAGERCE--GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF---TGRHCETFVD 1306
Query: 123 ECEEQRVCRNGRC---HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C + G C N P F C C PGF+ + +C +K G C A G
Sbjct: 1307 VCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQC-VHTASGPR 1365
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPH-GSC--ENLEPGYRCICDPGY 228
+ CP ++G C + P C H GSC + P Y C C P +
Sbjct: 1366 CF---CPSPRDCESG------CASSP--CQHGGSCHPQRQPPYYSCQCAPPF 1406
Score = 91.9 bits (218), Expect = 4e-18
Identities = 85/314 (27%), Positives = 130/314 (41%), Gaps = 42/314 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSY 61
NGG C +GI F C+C G+ G+ C +++EC +P + G C + G+Y
Sbjct: 998 NGGTCVDGI-----NSFSCLCPVGFT----GSFCLHEINECSSHPCL-NEGTCVDGLGTY 1047
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C G+ C + + S CK G CV + QC+C +G+ V
Sbjct: 1048 RCSCPLGYT---GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVS 1104
Query: 121 VDECEEQR------VCRN-GRCHNTPGSFRCECLPGFTLS---NDGRTCLGLKLGWGVSC 170
D +R +C++ G C N + C+C G+T S C G +C
Sbjct: 1105 CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATC 1164
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYH 229
Y C G N +++EC P C +G +C +L ++C C PG
Sbjct: 1165 SDFIGG----YRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPGTR 1218
Query: 230 PDADGLCRD-IDECDMHQSYCAGGQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDEC- 284
LC + ID+C GGQC + G ++C C P G R E ++ C + C
Sbjct: 1219 ---GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLS-NPCS 1274
Query: 285 -EGETETHYIESDY 297
EG + + +DY
Sbjct: 1275 SEGSLDCIQLTNDY 1288
Score = 91.1 bits (216), Expect = 7e-18
Identities = 78/291 (26%), Positives = 112/291 (38%), Gaps = 32/291 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA-GSY 61
NGG C + + + G C C G+ E C + G C + +Y
Sbjct: 75 NGGTC---VAQAMLGKATCRCASGFTG--EDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY 129
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VD 120
C C+ GF C D C + G C F C C G+ T C D
Sbjct: 130 ECTCQVGFTGKE---CQWTDACLSHPCANGSTCTTVANQFSCKCLTGF----TGQKCETD 182
Query: 121 VDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWG----VSCQACPA 175
V+EC+ C++G C N PGS++C+C GFT G+ C L + V+ C
Sbjct: 183 VNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSLYVPCAPSPCVNGGTCRQ 238
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADG 234
G + C G +I++C C +G C + Y C C P +
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNIDDCP--NHRCQNGGVCVDGVNTYNCRCPPQW--TGQF 294
Query: 235 LCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
D+DEC + + C GG C N G + CVC G + +ID+C
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD---DCSENIDDC 342
Score = 60.5 bits (140), Expect = 1e-08
Identities = 97/386 (25%), Positives = 135/386 (34%), Gaps = 53/386 (13%)
Query: 70 APTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
AP A C D + C + MC G+ C C G+ C D CE+ R
Sbjct: 21 APAHALQCRDGYEPCVNEGMC----VTYHNGTGYCKCPEGFLGEY----CQHRDPCEKNR 72
Query: 129 VCRNGRC--HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ---ACPAQGSELYAV 183
G C G C C GFT D + C C + Y
Sbjct: 73 CQNGGTCVAQAMLGKATCRCASGFT-GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYEC 131
Query: 184 LCPEG-PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR-DID 240
C G K+ D C + P C +GS C + + C C G+ C D++
Sbjct: 132 TCQVGFTGKECQWTDA--CLSHP--CANGSTCTTVANQFSCKCLTGFTGQK---CETDVN 184
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEG--TRHEPELQL-CRDIDECEGETETHYIESDY 297
ECD+ GG C N GS+ C CP+G ++ L + C G T + +
Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTF 244
Query: 298 ERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRR 356
E +P + E C N RC N GG C G ++ RC G
Sbjct: 245 ECNCLPGFEGSTCERNIDDCPNHRCQN--GGV---CVDG--VNTYNCRCPPQWTGQF--- 294
Query: 357 VVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDEC 415
C E LL+ C + G+ G++ G C ++D+C
Sbjct: 295 -----CTEDVDECLLQPNACQN----GGTCANRNGGYGCVCVNGWS---GDDCSENIDDC 342
Query: 416 ALSAELCAGGTCVNTDGSYRCDCPPG 441
A A G TC++ S+ C CP G
Sbjct: 343 AF-ASCTPGSTCIDRVASFSCMCPEG 367
Score = 46.8 bits (106), Expect = 2e-04
Identities = 86/353 (24%), Positives = 116/353 (32%), Gaps = 59/353 (16%)
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSNDGRTCLGL 162
C GY P G CV HN G+ C+C GF C
Sbjct: 28 CRDGYEPCVNEGMCVTY--------------HN--GTGYCKCPEGFLGEYCQHRDPCEKN 71
Query: 163 KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPG-Y 220
+ G +C A G C G + ++ + V C +G +C L Y
Sbjct: 72 RCQNGGTCVAQAMLGKA--TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY 129
Query: 221 RCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEG---TRHEPELQ 276
C C G+ C+ D C H CA G C A F+C C G + E ++
Sbjct: 130 ECTCQVGFTGKE---CQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
Query: 277 LCRDIDECEGETETHYIESDYERGDIPPTFPTR--TELASPCDNGRCINTHGGFECECEL 334
C C+ + Y+ P F + L PC C+N G C
Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQC-QCPQGFTGQYCDSLYVPCAPSPCVN---GGTCRQTG 240
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
+ + CL GS R +D C P + C G+
Sbjct: 241 DFTFECN---CLPGFEGSTCERNID-DC----PNHRCQNGGVCVDGV------------N 280
Query: 395 XXXXKGFAKLDGATC-RDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLD 445
+ + G C DVDEC L C GGTC N +G Y C C G + D
Sbjct: 281 TYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD 333
>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 157 bits (380), Expect = 1e-37
Identities = 127/464 (27%), Positives = 186/464 (40%), Gaps = 51/464 (10%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N C + GGF C+C PG++ G C +++EC+ NP V G+C + + CL
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQSNPCV-NNGQCVDKVNRFQCL 519
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD-VDE 123
C PGF T D+D+C++ G +C++ ++C C G+ T C + +D
Sbjct: 520 CPPGF--TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF----TGVLCEENIDN 573
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--- 180
C+ C +G+C + S+ C C PG+ G C ++ S C G +
Sbjct: 574 CDPDP-CHHGQCQDGIDSYTCICNPGYM----GAICSD-QIDECYS-SPCLNDGRCIDLV 626
Query: 181 --YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
Y C G S N + ++C + P C HG C + Y C+C PG+ + D
Sbjct: 627 NGYQCNCQPGTSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGFTGQRCNI--D 682
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEP---ELQLCRDID----ECEGETETH 291
IDEC + G C N F C+CPEG H ++ C C G +
Sbjct: 683 IDECASNPCR-KGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGY 741
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELG---YVLDATAQRCLD 347
D I L++PC NG C N G+ C C+ G Y C
Sbjct: 742 KCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECAS 801
Query: 348 N---RRGSCWRRVVDGQCEAAAPELLLRQECC---CSVGLAWGSXXXXXXXXXXXXXKGF 401
N +G+C+ + C P + CS +
Sbjct: 802 NPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLC 861
Query: 402 AK-LDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
A G C D+DEC +S G C NT GSY C+CPPG +
Sbjct: 862 APGWQGQRCTIDIDEC-ISKPCMNHGLCHNTQGSYMCECPPGFS 904
Score = 144 bits (349), Expect = 6e-34
Identities = 130/470 (27%), Positives = 199/470 (42%), Gaps = 67/470 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + G+EC C G+ G LC + +D C +P C G+C++ SYTC+
Sbjct: 541 CLNGAKCIDHPNGYECQCATGFT----GVLCEENIDNCDPDP--CHHGQCQDGIDSYTCI 594
Query: 65 CEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PG+ C+D +DEC + GRC++ +QC C+ G T+ ++ D+
Sbjct: 595 CNPGY---MGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPG---TSGVNCEINFDD 648
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C C +G C + + C C PGFT + D C G +C G
Sbjct: 649 C-ASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC----INGVNG 703
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
+ +CPEGP + + +NEC + P C HG+C GY+C+CD G+ G+ ++D
Sbjct: 704 FRCICPEGPHHPSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW----VGINCEVD 757
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG----ETETHYIE- 294
+ + + C GG C N + C C +G + Q+ +IDEC T + +
Sbjct: 758 KNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGY-NCQV--NIDECASNPCLNQGTCFDDI 814
Query: 295 SDYERGDIPPTF--PTRTELA----SPCDNGRCINTHGGFE---CECELGY--------V 337
S Y + P +T LA +PC+N FE C C G+ +
Sbjct: 815 SGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
Query: 338 LDATAQRCLD-----NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
+ ++ C++ N +GS G E + +C + GS
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDI--DDCLANPCQNGGSCMDGVNT 932
Query: 393 XXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G C+ D++EC LS GGTC + SY C C G
Sbjct: 933 FSCLCLPGFT---GDKCQTDMNEC-LSEPCKNGGTCSDYVNSYTCKCQAG 978
Score = 140 bits (338), Expect = 1e-32
Identities = 111/385 (28%), Positives = 164/385 (42%), Gaps = 52/385 (13%)
Query: 1 MTNGGMCTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNT 57
M N C + G C N DG F C C GY G C D++EC +P C+ C +
Sbjct: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP--CQNDATCLDK 474
Query: 58 AGSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG 116
G +TCLC PGF +C +++EC ++ G+CV+ FQC+C G+ T
Sbjct: 475 IGGFTCLCMPGFKGV---HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGP 527
Query: 117 AC-VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQA 172
C +D+D+C +C + P + C+C GFT + C G CQ
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQ- 585
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
G + Y +C G I+EC + P G C +L GY+C C PG
Sbjct: 586 ---DGIDSYTCICNPGYMGAICSDQIDECYSSP-CLNDGRCIDLVNGYQCNCQPG----T 637
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDEC------E 285
G+ +I+ D + C G C + ++CVC G Q C DIDEC +
Sbjct: 638 SGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG----QRCNIDIDECASNPCRK 693
Query: 286 GETETHYIESDY----ERGDIPPTFPTRTE-LASPCDNGRCINTHGGFECECELGYV--- 337
G T + + E P + E L++PC +G C G++C C+ G+V
Sbjct: 694 GATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGIN 753
Query: 338 LDATAQRCLDN--RRGSCWRRVVDG 360
+ CL N + G +V+G
Sbjct: 754 CEVDKNECLSNPCQNGGTCDNLVNG 778
Score = 136 bits (330), Expect = 1e-31
Identities = 128/456 (28%), Positives = 182/456 (39%), Gaps = 64/456 (14%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C N+ G+ C CK G++ G C+ ++DEC NP + +G C + YTC
Sbjct: 766 CQNGGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECASNPCL-NQGTCFDDISGYTCH 820
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGR-CVNSEG--SFQCVCEAGYRPTATRGACVDV 121
C P C V + + C+ C S S+ C+C G++ + +D+
Sbjct: 821 C---VLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQG---QRCTIDI 874
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
DEC + +G CHNT GS+ CEC PGF+ D CL G SC G
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCM----DGV 930
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
++ LC G + D D+NEC + P C + G+C + Y C C G+ D
Sbjct: 931 NTFSCLCLPGFTGDKCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF--DGVHCEN 986
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR--------HEPELQLCRDIDECEGETE 289
+I+EC S GG C + SF+C+CP G +E C + C
Sbjct: 987 NINEC-TESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLG 1045
Query: 290 THYIESDYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGYVLDATAQRCL 346
T+ G T L SPC N G C+ +C C G+
Sbjct: 1046 TY--RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW---------- 1093
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
+ V + C+ AA + E C G G+ G
Sbjct: 1094 ----AGAYCDVPNVSCDIAASRRGVLVEHLCQHS---GVCINAGNTHYCQCPLGYT---G 1143
Query: 407 ATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ C + +DECA S G TC + G YRC+C PG
Sbjct: 1144 SYCEEQLDECA-SNPCQHGATCSDFIGGYRCECVPG 1178
Score = 132 bits (319), Expect = 2e-30
Identities = 128/454 (28%), Positives = 182/454 (40%), Gaps = 57/454 (12%)
Query: 15 IDGGFECICKPGYESGSEGALC-RDVDECR-DNPRVCRR-GRCRNTAGSYTCLCEPGFAP 71
++G + C C GY+ GA C DVDEC N C G+C NT G++ C C G+A
Sbjct: 395 LNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
Query: 72 TAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCR 131
D++EC +D C++ G F C+C G++ ++++EC+
Sbjct: 451 PRCEM--DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCE---LEINECQSNPCVN 505
Query: 132 NGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG 188
NG+C + F+C C PGFT D C G C P G Y C G
Sbjct: 506 NGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP-NG---YECQCATG 561
Query: 189 PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD-IDECDMHQS 247
+ +I+ C P C HG C++ Y CIC+PGY +C D IDEC + S
Sbjct: 562 FTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGY---MGAICSDQIDEC--YSS 614
Query: 248 YCAG-GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD----YERGDI 302
C G+C + + C C GT + + D+C H I D Y
Sbjct: 615 PCLNDGRCIDLVNGYQCNCQPGT---SGVNCEINFDDCASNPCIHGICMDGINRYSCVCS 671
Query: 303 PPTFPTRTEL------ASPCDNG-RCINTHGGFECECELG---YVLDATAQRCLDNR--R 350
P R + ++PC G CIN GF C C G + CL N
Sbjct: 672 PGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIH 731
Query: 351 GSCWRRVVDGQCEAAAPELLL-----RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD 405
G+C + +C A + + + EC + G+ KGF
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGF---K 788
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDC 438
G C+ ++DECA S GTC + Y C C
Sbjct: 789 GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC 821
Score = 125 bits (302), Expect = 3e-28
Identities = 132/476 (27%), Positives = 190/476 (39%), Gaps = 74/476 (15%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N G C ++ G++C C+PG + G C + D+C NP C G C + Y+C+
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNP--CIHGICMDGINRYSCV 669
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG-YRPTATRGACVDVDE 123
C PGF T D+DECA++ KG C+N F+C+C G + P+ V+E
Sbjct: 670 CSPGF--TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYS----QVNE 723
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGSEL 180
C C +G C ++C C G+ N D CL G +C G
Sbjct: 724 CLSNP-CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL-VNG--- 778
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
Y C +G N +I+EC + P G+C + GY C C Y
Sbjct: 779 YRCTCKKGFKGYNCQVNIDECASNP-CLNQGTCFDDISGYTCHCVLPYTGK--------- 828
Query: 241 ECDMHQSYCAGGQCRNTA--------GSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C + C+ C N A S+TC+C G + + + DIDEC + ++
Sbjct: 829 NCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ---RCTIDIDECISKPCMNH 885
Query: 293 IESDYERG----DIPPTFPTRTE-------LASPCDNG-RCINTHGGFECECELGYVLD- 339
+G + PP F LA+PC NG C++ F C C G+ D
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDK 945
Query: 340 --ATAQRCLDN---RRGSCWRRVVDGQCEAAAPELLLR-----QECCCSVGLAWGSXXXX 389
CL G+C V C+ A + EC S G+
Sbjct: 946 CQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
Query: 390 XXXXXXXXXKGFAKLDGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPGLT 443
GF G+ C +++EC S+ C GTCV+ G+YRC CP G T
Sbjct: 1006 INSFSCLCPVGFT---GSFCLHEINEC--SSHPCLNEGTCVDGLGTYRCSCPLGYT 1056
Score = 120 bits (290), Expect = 8e-27
Identities = 93/346 (26%), Positives = 137/346 (39%), Gaps = 35/346 (10%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C NG+ GF CIC G S V+EC NP C G C Y C
Sbjct: 694 GATCINGV-----NGFRCICPEGPHHPS---CYSQVNECLSNP--CIHGNCTGGLSGYKC 743
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
LC+ G+ D +EC ++ GG C N ++C C+ G++ + V++DE
Sbjct: 744 LCDAGWVGINCE--VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ---VNIDE 798
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYA 182
C G C + + C C+ +T N + C + E Y
Sbjct: 799 CASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP-DADGLCRDIDE 241
LC G DI+EC + P HG C N + Y C C PG+ D + DID+
Sbjct: 859 CLCAPGWQGQRCTIDIDECISKP-CMNHGLCHNTQGSYMCECPPGFSGMDCE---EDIDD 914
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEGETETHYIES--- 295
C + GG C + +F+C+C P G + + ++ C G T + Y+ S
Sbjct: 915 C-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTC 973
Query: 296 ----DYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGY 336
++ TE S C NG C++ F C C +G+
Sbjct: 974 KCQAGFDGVHCENNINECTE--SSCFNGGTCVDGINSFSCLCPVGF 1017
Score = 116 bits (280), Expect = 1e-25
Identities = 121/457 (26%), Positives = 174/457 (38%), Gaps = 65/457 (14%)
Query: 7 CTNG-ICKNIDG--GFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYT 62
C N +CK + C+C PG++ G C D+DEC P + G C NT GSY
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECISKPCM-NHGLCHNTQGSYM 896
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDV 121
C C PGF+ D+D+C A+ GG C++ +F C+C G+ T C D+
Sbjct: 897 CECPPGFSGMDCE--EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF----TGDKCQTDM 950
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
+EC + G C + S+ C+C GF N+ C G +C G
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTC----VDGI 1006
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
++ LCP G + +INEC++ P G+C + YRC C GY
Sbjct: 1007 NSFSCLCPVGFTGSFCLHEINECSSHP-CLNEGTCVDGLGTYRCSCPLGYTGK------- 1058
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
C + C+ C+N TCV + + E Q C Y +
Sbjct: 1059 --NCQTLVNLCSRSPCKNKG---TCV-----QKKAESQCL-----CPSGWAGAYCDVPNV 1103
Query: 299 RGDIPPTFPTRTELASP-CDN-GRCINTHGGFECECELGYV---LDATAQRCLDN--RRG 351
DI + R L C + G CIN C+C LGY + C N + G
Sbjct: 1104 SCDIAAS--RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHG 1161
Query: 352 SCWRRVVDG-QCEAAAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD 405
+ + G +CE + EC G+ G
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR--- 1218
Query: 406 GATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C + +D+CA GG C++ G Y C C PG
Sbjct: 1219 GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPG 1255
Score = 116 bits (279), Expect = 2e-25
Identities = 121/470 (25%), Positives = 174/470 (37%), Gaps = 60/470 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGS 60
NGG+C +G+ + C C P + G C DVDEC P C+ G C N G
Sbjct: 271 NGGVCVDGV-----NTYNCRCPPQWT----GQFCTEDVDECLLQPNACQNGGTCANRNGG 321
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
Y C+C G++ ++D+CA S G C++ SF C+C P G
Sbjct: 322 YGCVCVNGWSGDDCS--ENIDDCAFASCTPGSTCIDRVASFSCMC-----PEGKAGLLCH 374
Query: 121 VDECEEQRVCRNGR-CHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACP 174
+D+ C G C P G + C C G+ + D C C
Sbjct: 375 LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCV 434
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDAD 233
+ C +G + DINEC + P C + +C + G+ C+C PG+
Sbjct: 435 NTDGAFHCE-CLKGYAGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFKGVHC 491
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
L +I+EC + GQC + F C+CP G P Q+ DID+C +
Sbjct: 492 EL--EINECQSNPC-VNNGQCVDKVNRFQCLCPPGFT-GPVCQI--DIDDCSSTPCLNGA 545
Query: 294 ES-DYERGDIPPTFPTRTEL----------ASPCDNGRCINTHGGFECECELGY---VLD 339
+ D+ G T + PC +G+C + + C C GY +
Sbjct: 546 KCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICS 605
Query: 340 ATAQRCLDN---RRGSCWRRVVDGQCE----AAAPELLLRQECCCSVGLAWGSXXXXXXX 392
C + G C V QC + + + C S G
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINR 665
Query: 393 XXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G C D+DECA S G TC+N +RC CP G
Sbjct: 666 YSCVCSPGFT---GQRCNIDIDECA-SNPCRKGATCINGVNGFRCICPEG 711
Score = 108 bits (260), Expect = 3e-23
Identities = 101/374 (27%), Positives = 151/374 (40%), Gaps = 52/374 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ F C+C PG+ G C+ D++EC P C+ G C + S
Sbjct: 922 NGGSCMDGV-----NTFSCLCLPGFT----GDKCQTDMNECLSEP--CKNGGTCSDYVNS 970
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
YTC C+ GF +C + ++EC S GG CV+ SF C+C G+ T C+
Sbjct: 971 YTCKCQAGFDGV---HCENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCL 1023
Query: 120 -DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+++EC G C + G++RC C G+T N +T + L + Q
Sbjct: 1024 HEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKN-CQTLVNLCSRSPCKNKGTCVQKK 1082
Query: 179 ELYAVLCPEG--------PSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYH 229
LCP G P+ A V C H G C N + C C GY
Sbjct: 1083 AESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY- 1141
Query: 230 PDADGLCRD-IDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECE 285
C + +DEC + G C + G + C C +G E E+ C++ C+
Sbjct: 1142 --TGSYCEEQLDECASNPCQ-HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQN-QPCQ 1197
Query: 286 GETETHYIESDYERGDIPPTFPTRTE------LASP-CDN-GRCINTHGGFECECELGYV 337
+ + ++ P T E P C N G+C++ GG+ C C G+
Sbjct: 1198 NGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA 1257
Query: 338 ---LDATAQRCLDN 348
+ CL N
Sbjct: 1258 GERCEGDINECLSN 1271
Score = 106 bits (255), Expect = 1e-22
Identities = 125/435 (28%), Positives = 162/435 (37%), Gaps = 48/435 (11%)
Query: 41 ECRDNPRVC-RRGRCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSE 98
+CRD C G C G+ C C GF YC D C + GG CV
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFL---GEYCQHRDPCEKNRCQNGGTCVAQA 83
Query: 99 --GSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNG-RCHN-TPGSFRCECLPGFTLSN 154
G C C +G+ T C R C NG CH + ++ C C GFT
Sbjct: 84 MLGKATCRCASGF--TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE 141
Query: 155 DGRT--CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG- 211
T CL G +C Q ++ C G + D+NEC +PG C HG
Sbjct: 142 CQWTDACLSHPCANGSTCTTVANQ----FSCKCLTGFTGQKCETDVNECD-IPGHCQHGG 196
Query: 212 SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAG-SFTCVC-P-- 266
+C NL Y+C C G+ G D S C GG CR T +F C C P
Sbjct: 197 TCLNLPGSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGF 252
Query: 267 EGTRHEPELQ-----LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP--CDNG 319
EG+ E + C++ C T+ + T L P C NG
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNG 312
Query: 320 -RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWR------RVVDGQC---EAAAPEL 369
C N +GG+ C C G+ D ++ D SC RV C E A L
Sbjct: 313 GTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLL 372
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALS-AELCA-GGT 426
+ C S G+ GA C DVDECA++ + C G
Sbjct: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGK 432
Query: 427 CVNTDGSYRCDCPPG 441
CVNTDG++ C+C G
Sbjct: 433 CVNTDGAFHCECLKG 447
Score = 100 bits (240), Expect = 9e-21
Identities = 80/270 (29%), Positives = 112/270 (41%), Gaps = 35/270 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
+G+C N C C GY G+ C + +DEC NP C+ G C + G Y C C
Sbjct: 1123 SGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASNP--CQHGATCSDFIGGYRCECV 1176
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD--VDEC 124
PG+ Y +VDEC GG C++ F+C C P TRG + +D+C
Sbjct: 1177 PGYQGVNCEY--EVDECQNQPCQNGGTCIDLVNHFKCSC-----PPGTRGLLCEENIDDC 1229
Query: 125 EEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C N G+C + G + C CLPGF D CL S Q +
Sbjct: 1230 ARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDC--IQLTND 1287
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSC---ENLEPGYRCICDPGYHPDADGLCR 237
Y +C + + ++ C +P G+C N+ G+ C C PG+ + C+
Sbjct: 1288 YLCVCRSAFTGRHCETFVDVCPQMP-CLNGGTCAVASNMPDGFICRCPPGF---SGARCQ 1343
Query: 238 DIDECDMHQSYC-AGGQCRNTAGSFTCVCP 266
C Q C G QC +TA C CP
Sbjct: 1344 --SSCG--QVKCRKGEQCVHTASGPRCFCP 1369
Score = 93.5 bits (222), Expect = 1e-18
Identities = 68/232 (29%), Positives = 97/232 (41%), Gaps = 31/232 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C ++ F+C C PG + G LC + +D+C P G+C + G Y+C
Sbjct: 1196 CQNGGTCIDLVNHFKCSCPPG----TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCR 1251
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGR--CVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C PGFA D++EC ++ G C+ + CVC + + R VD
Sbjct: 1252 CLPGFAGERCE--GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF---TGRHCETFVD 1306
Query: 123 ECEEQRVCRNGRC---HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C + G C N P F C C PGF+ + +C +K G C A G
Sbjct: 1307 VCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQC-VHTASGPR 1365
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPH-GSC--ENLEPGYRCICDPGY 228
+ CP ++G C + P C H GSC + P Y C C P +
Sbjct: 1366 CF---CPSPRDCESG------CASSP--CQHGGSCHPQRQPPYYSCQCAPPF 1406
Score = 91.9 bits (218), Expect = 4e-18
Identities = 85/314 (27%), Positives = 130/314 (41%), Gaps = 42/314 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSY 61
NGG C +GI F C+C G+ G+ C +++EC +P + G C + G+Y
Sbjct: 998 NGGTCVDGI-----NSFSCLCPVGFT----GSFCLHEINECSSHPCL-NEGTCVDGLGTY 1047
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C G+ C + + S CK G CV + QC+C +G+ V
Sbjct: 1048 RCSCPLGYT---GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVS 1104
Query: 121 VDECEEQR------VCRN-GRCHNTPGSFRCECLPGFTLS---NDGRTCLGLKLGWGVSC 170
D +R +C++ G C N + C+C G+T S C G +C
Sbjct: 1105 CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATC 1164
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYH 229
Y C G N +++EC P C +G +C +L ++C C PG
Sbjct: 1165 SDFIGG----YRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPGTR 1218
Query: 230 PDADGLCRD-IDECDMHQSYCAGGQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDEC- 284
LC + ID+C GGQC + G ++C C P G R E ++ C + C
Sbjct: 1219 ---GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLS-NPCS 1274
Query: 285 -EGETETHYIESDY 297
EG + + +DY
Sbjct: 1275 SEGSLDCIQLTNDY 1288
Score = 91.1 bits (216), Expect = 7e-18
Identities = 78/291 (26%), Positives = 112/291 (38%), Gaps = 32/291 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA-GSY 61
NGG C + + + G C C G+ E C + G C + +Y
Sbjct: 75 NGGTC---VAQAMLGKATCRCASGFTG--EDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY 129
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VD 120
C C+ GF C D C + G C F C C G+ T C D
Sbjct: 130 ECTCQVGFTGKE---CQWTDACLSHPCANGSTCTTVANQFSCKCLTGF----TGQKCETD 182
Query: 121 VDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWG----VSCQACPA 175
V+EC+ C++G C N PGS++C+C GFT G+ C L + V+ C
Sbjct: 183 VNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSLYVPCAPSPCVNGGTCRQ 238
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADG 234
G + C G +I++C C +G C + Y C C P +
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNIDDCP--NHRCQNGGVCVDGVNTYNCRCPPQW--TGQF 294
Query: 235 LCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
D+DEC + + C GG C N G + CVC G + +ID+C
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD---DCSENIDDC 342
Score = 60.5 bits (140), Expect = 1e-08
Identities = 97/386 (25%), Positives = 135/386 (34%), Gaps = 53/386 (13%)
Query: 70 APTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
AP A C D + C + MC G+ C C G+ C D CE+ R
Sbjct: 21 APAHALQCRDGYEPCVNEGMC----VTYHNGTGYCKCPEGFLGEY----CQHRDPCEKNR 72
Query: 129 VCRNGRC--HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ---ACPAQGSELYAV 183
G C G C C GFT D + C C + Y
Sbjct: 73 CQNGGTCVAQAMLGKATCRCASGFT-GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYEC 131
Query: 184 LCPEG-PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR-DID 240
C G K+ D C + P C +GS C + + C C G+ C D++
Sbjct: 132 TCQVGFTGKECQWTDA--CLSHP--CANGSTCTTVANQFSCKCLTGFTGQK---CETDVN 184
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEG--TRHEPELQL-CRDIDECEGETETHYIESDY 297
ECD+ GG C N GS+ C CP+G ++ L + C G T + +
Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTF 244
Query: 298 ERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRR 356
E +P + E C N RC N GG C G ++ RC G
Sbjct: 245 ECNCLPGFEGSTCERNIDDCPNHRCQN--GGV---CVDG--VNTYNCRCPPQWTGQF--- 294
Query: 357 VVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDEC 415
C E LL+ C + G+ G++ G C ++D+C
Sbjct: 295 -----CTEDVDECLLQPNACQN----GGTCANRNGGYGCVCVNGWS---GDDCSENIDDC 342
Query: 416 ALSAELCAGGTCVNTDGSYRCDCPPG 441
A A G TC++ S+ C CP G
Sbjct: 343 AF-ASCTPGSTCIDRVASFSCMCPEG 367
Score = 46.8 bits (106), Expect = 2e-04
Identities = 86/353 (24%), Positives = 116/353 (32%), Gaps = 59/353 (16%)
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSNDGRTCLGL 162
C GY P G CV HN G+ C+C GF C
Sbjct: 28 CRDGYEPCVNEGMCVTY--------------HN--GTGYCKCPEGFLGEYCQHRDPCEKN 71
Query: 163 KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPG-Y 220
+ G +C A G C G + ++ + V C +G +C L Y
Sbjct: 72 RCQNGGTCVAQAMLGKA--TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY 129
Query: 221 RCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEG---TRHEPELQ 276
C C G+ C+ D C H CA G C A F+C C G + E ++
Sbjct: 130 ECTCQVGFTGKE---CQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
Query: 277 LCRDIDECEGETETHYIESDYERGDIPPTFPTR--TELASPCDNGRCINTHGGFECECEL 334
C C+ + Y+ P F + L PC C+N G C
Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQC-QCPQGFTGQYCDSLYVPCAPSPCVN---GGTCRQTG 240
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
+ + CL GS R +D C P + C G+
Sbjct: 241 DFTFECN---CLPGFEGSTCERNID-DC----PNHRCQNGGVCVDGV------------N 280
Query: 395 XXXXKGFAKLDGATC-RDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLD 445
+ + G C DVDEC L C GGTC N +G Y C C G + D
Sbjct: 281 TYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD 333
>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 157 bits (380), Expect = 1e-37
Identities = 127/464 (27%), Positives = 186/464 (40%), Gaps = 51/464 (10%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N C + GGF C+C PG++ G C +++EC+ NP V G+C + + CL
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQSNPCV-NNGQCVDKVNRFQCL 519
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD-VDE 123
C PGF T D+D+C++ G +C++ ++C C G+ T C + +D
Sbjct: 520 CPPGF--TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF----TGVLCEENIDN 573
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--- 180
C+ C +G+C + S+ C C PG+ G C ++ S C G +
Sbjct: 574 CDPDP-CHHGQCQDGIDSYTCICNPGYM----GAICSD-QIDECYS-SPCLNDGRCIDLV 626
Query: 181 --YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
Y C G S N + ++C + P C HG C + Y C+C PG+ + D
Sbjct: 627 NGYQCNCQPGTSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGFTGQRCNI--D 682
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEP---ELQLCRDID----ECEGETETH 291
IDEC + G C N F C+CPEG H ++ C C G +
Sbjct: 683 IDECASNPCR-KGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGY 741
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELG---YVLDATAQRCLD 347
D I L++PC NG C N G+ C C+ G Y C
Sbjct: 742 KCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECAS 801
Query: 348 N---RRGSCWRRVVDGQCEAAAPELLLRQECC---CSVGLAWGSXXXXXXXXXXXXXKGF 401
N +G+C+ + C P + CS +
Sbjct: 802 NPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLC 861
Query: 402 AK-LDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
A G C D+DEC +S G C NT GSY C+CPPG +
Sbjct: 862 APGWQGQRCTIDIDEC-ISKPCMNHGLCHNTQGSYMCECPPGFS 904
Score = 144 bits (349), Expect = 6e-34
Identities = 130/470 (27%), Positives = 199/470 (42%), Gaps = 67/470 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + G+EC C G+ G LC + +D C +P C G+C++ SYTC+
Sbjct: 541 CLNGAKCIDHPNGYECQCATGFT----GVLCEENIDNCDPDP--CHHGQCQDGIDSYTCI 594
Query: 65 CEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PG+ C+D +DEC + GRC++ +QC C+ G T+ ++ D+
Sbjct: 595 CNPGY---MGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPG---TSGVNCEINFDD 648
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C C +G C + + C C PGFT + D C G +C G
Sbjct: 649 C-ASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC----INGVNG 703
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
+ +CPEGP + + +NEC + P C HG+C GY+C+CD G+ G+ ++D
Sbjct: 704 FRCICPEGPHHPSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW----VGINCEVD 757
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG----ETETHYIE- 294
+ + + C GG C N + C C +G + Q+ +IDEC T + +
Sbjct: 758 KNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGY-NCQV--NIDECASNPCLNQGTCFDDI 814
Query: 295 SDYERGDIPPTF--PTRTELA----SPCDNGRCINTHGGFE---CECELGY--------V 337
S Y + P +T LA +PC+N FE C C G+ +
Sbjct: 815 SGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
Query: 338 LDATAQRCLD-----NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
+ ++ C++ N +GS G E + +C + GS
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDI--DDCLANPCQNGGSCMDGVNT 932
Query: 393 XXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G C+ D++EC LS GGTC + SY C C G
Sbjct: 933 FSCLCLPGFT---GDKCQTDMNEC-LSEPCKNGGTCSDYVNSYTCKCQAG 978
Score = 140 bits (338), Expect = 1e-32
Identities = 111/385 (28%), Positives = 164/385 (42%), Gaps = 52/385 (13%)
Query: 1 MTNGGMCTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNT 57
M N C + G C N DG F C C GY G C D++EC +P C+ C +
Sbjct: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP--CQNDATCLDK 474
Query: 58 AGSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG 116
G +TCLC PGF +C +++EC ++ G+CV+ FQC+C G+ T
Sbjct: 475 IGGFTCLCMPGFKGV---HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGP 527
Query: 117 AC-VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQA 172
C +D+D+C +C + P + C+C GFT + C G CQ
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQ- 585
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
G + Y +C G I+EC + P G C +L GY+C C PG
Sbjct: 586 ---DGIDSYTCICNPGYMGAICSDQIDECYSSP-CLNDGRCIDLVNGYQCNCQPG----T 637
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDEC------E 285
G+ +I+ D + C G C + ++CVC G Q C DIDEC +
Sbjct: 638 SGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG----QRCNIDIDECASNPCRK 693
Query: 286 GETETHYIESDY----ERGDIPPTFPTRTE-LASPCDNGRCINTHGGFECECELGYV--- 337
G T + + E P + E L++PC +G C G++C C+ G+V
Sbjct: 694 GATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGIN 753
Query: 338 LDATAQRCLDN--RRGSCWRRVVDG 360
+ CL N + G +V+G
Sbjct: 754 CEVDKNECLSNPCQNGGTCDNLVNG 778
Score = 136 bits (330), Expect = 1e-31
Identities = 128/456 (28%), Positives = 182/456 (39%), Gaps = 64/456 (14%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C N+ G+ C CK G++ G C+ ++DEC NP + +G C + YTC
Sbjct: 766 CQNGGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECASNPCL-NQGTCFDDISGYTCH 820
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGR-CVNSEG--SFQCVCEAGYRPTATRGACVDV 121
C P C V + + C+ C S S+ C+C G++ + +D+
Sbjct: 821 C---VLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQG---QRCTIDI 874
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
DEC + +G CHNT GS+ CEC PGF+ D CL G SC G
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCM----DGV 930
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
++ LC G + D D+NEC + P C + G+C + Y C C G+ D
Sbjct: 931 NTFSCLCLPGFTGDKCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF--DGVHCEN 986
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR--------HEPELQLCRDIDECEGETE 289
+I+EC S GG C + SF+C+CP G +E C + C
Sbjct: 987 NINEC-TESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLG 1045
Query: 290 THYIESDYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGYVLDATAQRCL 346
T+ G T L SPC N G C+ +C C G+
Sbjct: 1046 TY--RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW---------- 1093
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
+ V + C+ AA + E C G G+ G
Sbjct: 1094 ----AGAYCDVPNVSCDIAASRRGVLVEHLCQHS---GVCINAGNTHYCQCPLGYT---G 1143
Query: 407 ATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ C + +DECA S G TC + G YRC+C PG
Sbjct: 1144 SYCEEQLDECA-SNPCQHGATCSDFIGGYRCECVPG 1178
Score = 132 bits (319), Expect = 2e-30
Identities = 128/454 (28%), Positives = 182/454 (40%), Gaps = 57/454 (12%)
Query: 15 IDGGFECICKPGYESGSEGALC-RDVDECR-DNPRVCRR-GRCRNTAGSYTCLCEPGFAP 71
++G + C C GY+ GA C DVDEC N C G+C NT G++ C C G+A
Sbjct: 395 LNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
Query: 72 TAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCR 131
D++EC +D C++ G F C+C G++ ++++EC+
Sbjct: 451 PRCEM--DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCE---LEINECQSNPCVN 505
Query: 132 NGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG 188
NG+C + F+C C PGFT D C G C P G Y C G
Sbjct: 506 NGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP-NG---YECQCATG 561
Query: 189 PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD-IDECDMHQS 247
+ +I+ C P C HG C++ Y CIC+PGY +C D IDEC + S
Sbjct: 562 FTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGY---MGAICSDQIDEC--YSS 614
Query: 248 YCAG-GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD----YERGDI 302
C G+C + + C C GT + + D+C H I D Y
Sbjct: 615 PCLNDGRCIDLVNGYQCNCQPGT---SGVNCEINFDDCASNPCIHGICMDGINRYSCVCS 671
Query: 303 PPTFPTRTEL------ASPCDNG-RCINTHGGFECECELG---YVLDATAQRCLDNR--R 350
P R + ++PC G CIN GF C C G + CL N
Sbjct: 672 PGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIH 731
Query: 351 GSCWRRVVDGQCEAAAPELLL-----RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD 405
G+C + +C A + + + EC + G+ KGF
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGF---K 788
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDC 438
G C+ ++DECA S GTC + Y C C
Sbjct: 789 GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC 821
Score = 125 bits (302), Expect = 3e-28
Identities = 132/476 (27%), Positives = 190/476 (39%), Gaps = 74/476 (15%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N G C ++ G++C C+PG + G C + D+C NP C G C + Y+C+
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNP--CIHGICMDGINRYSCV 669
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG-YRPTATRGACVDVDE 123
C PGF T D+DECA++ KG C+N F+C+C G + P+ V+E
Sbjct: 670 CSPGF--TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYS----QVNE 723
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGSEL 180
C C +G C ++C C G+ N D CL G +C G
Sbjct: 724 CLSNP-CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL-VNG--- 778
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
Y C +G N +I+EC + P G+C + GY C C Y
Sbjct: 779 YRCTCKKGFKGYNCQVNIDECASNP-CLNQGTCFDDISGYTCHCVLPYTGK--------- 828
Query: 241 ECDMHQSYCAGGQCRNTA--------GSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C + C+ C N A S+TC+C G + + + DIDEC + ++
Sbjct: 829 NCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ---RCTIDIDECISKPCMNH 885
Query: 293 IESDYERG----DIPPTFPTRTE-------LASPCDNG-RCINTHGGFECECELGYVLD- 339
+G + PP F LA+PC NG C++ F C C G+ D
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDK 945
Query: 340 --ATAQRCLDN---RRGSCWRRVVDGQCEAAAPELLLR-----QECCCSVGLAWGSXXXX 389
CL G+C V C+ A + EC S G+
Sbjct: 946 CQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
Query: 390 XXXXXXXXXKGFAKLDGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPGLT 443
GF G+ C +++EC S+ C GTCV+ G+YRC CP G T
Sbjct: 1006 INSFSCLCPVGFT---GSFCLHEINEC--SSHPCLNEGTCVDGLGTYRCSCPLGYT 1056
Score = 120 bits (290), Expect = 8e-27
Identities = 93/346 (26%), Positives = 137/346 (39%), Gaps = 35/346 (10%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C NG+ GF CIC G S V+EC NP C G C Y C
Sbjct: 694 GATCINGV-----NGFRCICPEGPHHPS---CYSQVNECLSNP--CIHGNCTGGLSGYKC 743
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
LC+ G+ D +EC ++ GG C N ++C C+ G++ + V++DE
Sbjct: 744 LCDAGWVGINCE--VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ---VNIDE 798
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYA 182
C G C + + C C+ +T N + C + E Y
Sbjct: 799 CASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP-DADGLCRDIDE 241
LC G DI+EC + P HG C N + Y C C PG+ D + DID+
Sbjct: 859 CLCAPGWQGQRCTIDIDECISKP-CMNHGLCHNTQGSYMCECPPGFSGMDCE---EDIDD 914
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEGETETHYIES--- 295
C + GG C + +F+C+C P G + + ++ C G T + Y+ S
Sbjct: 915 C-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTC 973
Query: 296 ----DYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGY 336
++ TE S C NG C++ F C C +G+
Sbjct: 974 KCQAGFDGVHCENNINECTE--SSCFNGGTCVDGINSFSCLCPVGF 1017
Score = 116 bits (280), Expect = 1e-25
Identities = 121/457 (26%), Positives = 174/457 (38%), Gaps = 65/457 (14%)
Query: 7 CTNG-ICKNIDG--GFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYT 62
C N +CK + C+C PG++ G C D+DEC P + G C NT GSY
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECISKPCM-NHGLCHNTQGSYM 896
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDV 121
C C PGF+ D+D+C A+ GG C++ +F C+C G+ T C D+
Sbjct: 897 CECPPGFSGMDCE--EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF----TGDKCQTDM 950
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
+EC + G C + S+ C+C GF N+ C G +C G
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTC----VDGI 1006
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
++ LCP G + +INEC++ P G+C + YRC C GY
Sbjct: 1007 NSFSCLCPVGFTGSFCLHEINECSSHP-CLNEGTCVDGLGTYRCSCPLGYTGK------- 1058
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
C + C+ C+N TCV + + E Q C Y +
Sbjct: 1059 --NCQTLVNLCSRSPCKNKG---TCV-----QKKAESQCL-----CPSGWAGAYCDVPNV 1103
Query: 299 RGDIPPTFPTRTELASP-CDN-GRCINTHGGFECECELGYV---LDATAQRCLDN--RRG 351
DI + R L C + G CIN C+C LGY + C N + G
Sbjct: 1104 SCDIAAS--RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHG 1161
Query: 352 SCWRRVVDG-QCEAAAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD 405
+ + G +CE + EC G+ G
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR--- 1218
Query: 406 GATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C + +D+CA GG C++ G Y C C PG
Sbjct: 1219 GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPG 1255
Score = 116 bits (279), Expect = 2e-25
Identities = 121/470 (25%), Positives = 174/470 (37%), Gaps = 60/470 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGS 60
NGG+C +G+ + C C P + G C DVDEC P C+ G C N G
Sbjct: 271 NGGVCVDGV-----NTYNCRCPPQWT----GQFCTEDVDECLLQPNACQNGGTCANRNGG 321
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
Y C+C G++ ++D+CA S G C++ SF C+C P G
Sbjct: 322 YGCVCVNGWSGDDCS--ENIDDCAFASCTPGSTCIDRVASFSCMC-----PEGKAGLLCH 374
Query: 121 VDECEEQRVCRNGR-CHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACP 174
+D+ C G C P G + C C G+ + D C C
Sbjct: 375 LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCV 434
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDAD 233
+ C +G + DINEC + P C + +C + G+ C+C PG+
Sbjct: 435 NTDGAFHCE-CLKGYAGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFKGVHC 491
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
L +I+EC + GQC + F C+CP G P Q+ DID+C +
Sbjct: 492 EL--EINECQSNPC-VNNGQCVDKVNRFQCLCPPGFT-GPVCQI--DIDDCSSTPCLNGA 545
Query: 294 ES-DYERGDIPPTFPTRTEL----------ASPCDNGRCINTHGGFECECELGY---VLD 339
+ D+ G T + PC +G+C + + C C GY +
Sbjct: 546 KCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICS 605
Query: 340 ATAQRCLDN---RRGSCWRRVVDGQCE----AAAPELLLRQECCCSVGLAWGSXXXXXXX 392
C + G C V QC + + + C S G
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINR 665
Query: 393 XXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G C D+DECA S G TC+N +RC CP G
Sbjct: 666 YSCVCSPGFT---GQRCNIDIDECA-SNPCRKGATCINGVNGFRCICPEG 711
Score = 108 bits (260), Expect = 3e-23
Identities = 101/374 (27%), Positives = 151/374 (40%), Gaps = 52/374 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ F C+C PG+ G C+ D++EC P C+ G C + S
Sbjct: 922 NGGSCMDGV-----NTFSCLCLPGFT----GDKCQTDMNECLSEP--CKNGGTCSDYVNS 970
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
YTC C+ GF +C + ++EC S GG CV+ SF C+C G+ T C+
Sbjct: 971 YTCKCQAGFDGV---HCENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCL 1023
Query: 120 -DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+++EC G C + G++RC C G+T N +T + L + Q
Sbjct: 1024 HEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKN-CQTLVNLCSRSPCKNKGTCVQKK 1082
Query: 179 ELYAVLCPEG--------PSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYH 229
LCP G P+ A V C H G C N + C C GY
Sbjct: 1083 AESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY- 1141
Query: 230 PDADGLCRD-IDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECE 285
C + +DEC + G C + G + C C +G E E+ C++ C+
Sbjct: 1142 --TGSYCEEQLDECASNPCQ-HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQN-QPCQ 1197
Query: 286 GETETHYIESDYERGDIPPTFPTRTE------LASP-CDN-GRCINTHGGFECECELGYV 337
+ + ++ P T E P C N G+C++ GG+ C C G+
Sbjct: 1198 NGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA 1257
Query: 338 ---LDATAQRCLDN 348
+ CL N
Sbjct: 1258 GERCEGDINECLSN 1271
Score = 106 bits (255), Expect = 1e-22
Identities = 125/435 (28%), Positives = 162/435 (37%), Gaps = 48/435 (11%)
Query: 41 ECRDNPRVC-RRGRCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSE 98
+CRD C G C G+ C C GF YC D C + GG CV
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFL---GEYCQHRDPCEKNRCQNGGTCVAQA 83
Query: 99 --GSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNG-RCHN-TPGSFRCECLPGFTLSN 154
G C C +G+ T C R C NG CH + ++ C C GFT
Sbjct: 84 MLGKATCRCASGF--TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE 141
Query: 155 DGRT--CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG- 211
T CL G +C Q ++ C G + D+NEC +PG C HG
Sbjct: 142 CQWTDACLSHPCANGSTCTTVANQ----FSCKCLTGFTGQKCETDVNECD-IPGHCQHGG 196
Query: 212 SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAG-SFTCVC-P-- 266
+C NL Y+C C G+ G D S C GG CR T +F C C P
Sbjct: 197 TCLNLPGSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGF 252
Query: 267 EGTRHEPELQ-----LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP--CDNG 319
EG+ E + C++ C T+ + T L P C NG
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNG 312
Query: 320 -RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWR------RVVDGQC---EAAAPEL 369
C N +GG+ C C G+ D ++ D SC RV C E A L
Sbjct: 313 GTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLL 372
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALS-AELCA-GGT 426
+ C S G+ GA C DVDECA++ + C G
Sbjct: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGK 432
Query: 427 CVNTDGSYRCDCPPG 441
CVNTDG++ C+C G
Sbjct: 433 CVNTDGAFHCECLKG 447
Score = 100 bits (240), Expect = 9e-21
Identities = 80/270 (29%), Positives = 112/270 (41%), Gaps = 35/270 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
+G+C N C C GY G+ C + +DEC NP C+ G C + G Y C C
Sbjct: 1123 SGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASNP--CQHGATCSDFIGGYRCECV 1176
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD--VDEC 124
PG+ Y +VDEC GG C++ F+C C P TRG + +D+C
Sbjct: 1177 PGYQGVNCEY--EVDECQNQPCQNGGTCIDLVNHFKCSC-----PPGTRGLLCEENIDDC 1229
Query: 125 EEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C N G+C + G + C CLPGF D CL S Q +
Sbjct: 1230 ARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDC--IQLTND 1287
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSC---ENLEPGYRCICDPGYHPDADGLCR 237
Y +C + + ++ C +P G+C N+ G+ C C PG+ + C+
Sbjct: 1288 YLCVCRSAFTGRHCETFVDVCPQMP-CLNGGTCAVASNMPDGFICRCPPGF---SGARCQ 1343
Query: 238 DIDECDMHQSYC-AGGQCRNTAGSFTCVCP 266
C Q C G QC +TA C CP
Sbjct: 1344 --SSCG--QVKCRKGEQCVHTASGPRCFCP 1369
Score = 93.5 bits (222), Expect = 1e-18
Identities = 68/232 (29%), Positives = 97/232 (41%), Gaps = 31/232 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C ++ F+C C PG + G LC + +D+C P G+C + G Y+C
Sbjct: 1196 CQNGGTCIDLVNHFKCSCPPG----TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCR 1251
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGR--CVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C PGFA D++EC ++ G C+ + CVC + + R VD
Sbjct: 1252 CLPGFAGERCE--GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF---TGRHCETFVD 1306
Query: 123 ECEEQRVCRNGRC---HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C + G C N P F C C PGF+ + +C +K G C A G
Sbjct: 1307 VCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQC-VHTASGPR 1365
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPH-GSC--ENLEPGYRCICDPGY 228
+ CP ++G C + P C H GSC + P Y C C P +
Sbjct: 1366 CF---CPSPRDCESG------CASSP--CQHGGSCHPQRQPPYYSCQCAPPF 1406
Score = 91.9 bits (218), Expect = 4e-18
Identities = 85/314 (27%), Positives = 130/314 (41%), Gaps = 42/314 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSY 61
NGG C +GI F C+C G+ G+ C +++EC +P + G C + G+Y
Sbjct: 998 NGGTCVDGI-----NSFSCLCPVGFT----GSFCLHEINECSSHPCL-NEGTCVDGLGTY 1047
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C G+ C + + S CK G CV + QC+C +G+ V
Sbjct: 1048 RCSCPLGYT---GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVS 1104
Query: 121 VDECEEQR------VCRN-GRCHNTPGSFRCECLPGFTLS---NDGRTCLGLKLGWGVSC 170
D +R +C++ G C N + C+C G+T S C G +C
Sbjct: 1105 CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATC 1164
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYH 229
Y C G N +++EC P C +G +C +L ++C C PG
Sbjct: 1165 SDFIGG----YRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPGTR 1218
Query: 230 PDADGLCRD-IDECDMHQSYCAGGQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDEC- 284
LC + ID+C GGQC + G ++C C P G R E ++ C + C
Sbjct: 1219 ---GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLS-NPCS 1274
Query: 285 -EGETETHYIESDY 297
EG + + +DY
Sbjct: 1275 SEGSLDCIQLTNDY 1288
Score = 91.1 bits (216), Expect = 7e-18
Identities = 78/291 (26%), Positives = 112/291 (38%), Gaps = 32/291 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA-GSY 61
NGG C + + + G C C G+ E C + G C + +Y
Sbjct: 75 NGGTC---VAQAMLGKATCRCASGFTG--EDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY 129
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VD 120
C C+ GF C D C + G C F C C G+ T C D
Sbjct: 130 ECTCQVGFTGKE---CQWTDACLSHPCANGSTCTTVANQFSCKCLTGF----TGQKCETD 182
Query: 121 VDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWG----VSCQACPA 175
V+EC+ C++G C N PGS++C+C GFT G+ C L + V+ C
Sbjct: 183 VNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSLYVPCAPSPCVNGGTCRQ 238
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADG 234
G + C G +I++C C +G C + Y C C P +
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNIDDCP--NHRCQNGGVCVDGVNTYNCRCPPQW--TGQF 294
Query: 235 LCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
D+DEC + + C GG C N G + CVC G + +ID+C
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD---DCSENIDDC 342
Score = 60.5 bits (140), Expect = 1e-08
Identities = 97/386 (25%), Positives = 135/386 (34%), Gaps = 53/386 (13%)
Query: 70 APTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
AP A C D + C + MC G+ C C G+ C D CE+ R
Sbjct: 21 APAHALQCRDGYEPCVNEGMC----VTYHNGTGYCKCPEGFLGEY----CQHRDPCEKNR 72
Query: 129 VCRNGRC--HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ---ACPAQGSELYAV 183
G C G C C GFT D + C C + Y
Sbjct: 73 CQNGGTCVAQAMLGKATCRCASGFT-GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYEC 131
Query: 184 LCPEG-PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR-DID 240
C G K+ D C + P C +GS C + + C C G+ C D++
Sbjct: 132 TCQVGFTGKECQWTDA--CLSHP--CANGSTCTTVANQFSCKCLTGFTGQK---CETDVN 184
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEG--TRHEPELQL-CRDIDECEGETETHYIESDY 297
ECD+ GG C N GS+ C CP+G ++ L + C G T + +
Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTF 244
Query: 298 ERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRR 356
E +P + E C N RC N GG C G ++ RC G
Sbjct: 245 ECNCLPGFEGSTCERNIDDCPNHRCQN--GGV---CVDG--VNTYNCRCPPQWTGQF--- 294
Query: 357 VVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDEC 415
C E LL+ C + G+ G++ G C ++D+C
Sbjct: 295 -----CTEDVDECLLQPNACQN----GGTCANRNGGYGCVCVNGWS---GDDCSENIDDC 342
Query: 416 ALSAELCAGGTCVNTDGSYRCDCPPG 441
A A G TC++ S+ C CP G
Sbjct: 343 AF-ASCTPGSTCIDRVASFSCMCPEG 367
Score = 46.8 bits (106), Expect = 2e-04
Identities = 86/353 (24%), Positives = 116/353 (32%), Gaps = 59/353 (16%)
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSNDGRTCLGL 162
C GY P G CV HN G+ C+C GF C
Sbjct: 28 CRDGYEPCVNEGMCVTY--------------HN--GTGYCKCPEGFLGEYCQHRDPCEKN 71
Query: 163 KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPG-Y 220
+ G +C A G C G + ++ + V C +G +C L Y
Sbjct: 72 RCQNGGTCVAQAMLGKA--TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY 129
Query: 221 RCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEG---TRHEPELQ 276
C C G+ C+ D C H CA G C A F+C C G + E ++
Sbjct: 130 ECTCQVGFTGKE---CQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
Query: 277 LCRDIDECEGETETHYIESDYERGDIPPTFPTR--TELASPCDNGRCINTHGGFECECEL 334
C C+ + Y+ P F + L PC C+N G C
Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQC-QCPQGFTGQYCDSLYVPCAPSPCVN---GGTCRQTG 240
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
+ + CL GS R +D C P + C G+
Sbjct: 241 DFTFECN---CLPGFEGSTCERNID-DC----PNHRCQNGGVCVDGV------------N 280
Query: 395 XXXXKGFAKLDGATC-RDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLD 445
+ + G C DVDEC L C GGTC N +G Y C C G + D
Sbjct: 281 TYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD 333
>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
Length = 2471
Score = 157 bits (380), Expect = 1e-37
Identities = 127/464 (27%), Positives = 186/464 (40%), Gaps = 51/464 (10%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N C + GGF C+C PG++ G C +++EC+ NP V G+C + + CL
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQSNPCV-NNGQCVDKVNRFQCL 519
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD-VDE 123
C PGF T D+D+C++ G +C++ ++C C G+ T C + +D
Sbjct: 520 CPPGF--TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF----TGVLCEENIDN 573
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--- 180
C+ C +G+C + S+ C C PG+ G C ++ S C G +
Sbjct: 574 CDPDP-CHHGQCQDGIDSYTCICNPGYM----GAICSD-QIDECYS-SPCLNDGRCIDLV 626
Query: 181 --YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
Y C G S N + ++C + P C HG C + Y C+C PG+ + D
Sbjct: 627 NGYQCNCQPGTSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGFTGQRCNI--D 682
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEP---ELQLCRDID----ECEGETETH 291
IDEC + G C N F C+CPEG H ++ C C G +
Sbjct: 683 IDECASNPCR-KGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGY 741
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELG---YVLDATAQRCLD 347
D I L++PC NG C N G+ C C+ G Y C
Sbjct: 742 KCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECAS 801
Query: 348 N---RRGSCWRRVVDGQCEAAAPELLLRQECC---CSVGLAWGSXXXXXXXXXXXXXKGF 401
N +G+C+ + C P + CS +
Sbjct: 802 NPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLC 861
Query: 402 AK-LDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
A G C D+DEC +S G C NT GSY C+CPPG +
Sbjct: 862 APGWQGQRCTIDIDEC-ISKPCMNHGLCHNTQGSYMCECPPGFS 904
Score = 144 bits (349), Expect = 6e-34
Identities = 130/470 (27%), Positives = 199/470 (42%), Gaps = 67/470 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + G+EC C G+ G LC + +D C +P C G+C++ SYTC+
Sbjct: 541 CLNGAKCIDHPNGYECQCATGFT----GVLCEENIDNCDPDP--CHHGQCQDGIDSYTCI 594
Query: 65 CEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PG+ C+D +DEC + GRC++ +QC C+ G T+ ++ D+
Sbjct: 595 CNPGY---MGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPG---TSGVNCEINFDD 648
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C C +G C + + C C PGFT + D C G +C G
Sbjct: 649 C-ASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC----INGVNG 703
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
+ +CPEGP + + +NEC + P C HG+C GY+C+CD G+ G+ ++D
Sbjct: 704 FRCICPEGPHHPSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW----VGINCEVD 757
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG----ETETHYIE- 294
+ + + C GG C N + C C +G + Q+ +IDEC T + +
Sbjct: 758 KNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGY-NCQV--NIDECASNPCLNQGTCFDDI 814
Query: 295 SDYERGDIPPTF--PTRTELA----SPCDNGRCINTHGGFE---CECELGY--------V 337
S Y + P +T LA +PC+N FE C C G+ +
Sbjct: 815 SGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
Query: 338 LDATAQRCLD-----NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
+ ++ C++ N +GS G E + +C + GS
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDI--DDCLANPCQNGGSCMDGVNT 932
Query: 393 XXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G C+ D++EC LS GGTC + SY C C G
Sbjct: 933 FSCLCLPGFT---GDKCQTDMNEC-LSEPCKNGGTCSDYVNSYTCKCQAG 978
Score = 140 bits (338), Expect = 1e-32
Identities = 111/385 (28%), Positives = 164/385 (42%), Gaps = 52/385 (13%)
Query: 1 MTNGGMCTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNT 57
M N C + G C N DG F C C GY G C D++EC +P C+ C +
Sbjct: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP--CQNDATCLDK 474
Query: 58 AGSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG 116
G +TCLC PGF +C +++EC ++ G+CV+ FQC+C G+ T
Sbjct: 475 IGGFTCLCMPGFKGV---HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGP 527
Query: 117 AC-VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQA 172
C +D+D+C +C + P + C+C GFT + C G CQ
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQ- 585
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
G + Y +C G I+EC + P G C +L GY+C C PG
Sbjct: 586 ---DGIDSYTCICNPGYMGAICSDQIDECYSSP-CLNDGRCIDLVNGYQCNCQPG----T 637
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDEC------E 285
G+ +I+ D + C G C + ++CVC G Q C DIDEC +
Sbjct: 638 SGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG----QRCNIDIDECASNPCRK 693
Query: 286 GETETHYIESDY----ERGDIPPTFPTRTE-LASPCDNGRCINTHGGFECECELGYV--- 337
G T + + E P + E L++PC +G C G++C C+ G+V
Sbjct: 694 GATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGIN 753
Query: 338 LDATAQRCLDN--RRGSCWRRVVDG 360
+ CL N + G +V+G
Sbjct: 754 CEVDKNECLSNPCQNGGTCDNLVNG 778
Score = 136 bits (330), Expect = 1e-31
Identities = 128/456 (28%), Positives = 182/456 (39%), Gaps = 64/456 (14%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C N+ G+ C CK G++ G C+ ++DEC NP + +G C + YTC
Sbjct: 766 CQNGGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECASNPCL-NQGTCFDDISGYTCH 820
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGR-CVNSEG--SFQCVCEAGYRPTATRGACVDV 121
C P C V + + C+ C S S+ C+C G++ + +D+
Sbjct: 821 C---VLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQG---QRCTIDI 874
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
DEC + +G CHNT GS+ CEC PGF+ D CL G SC G
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCM----DGV 930
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
++ LC G + D D+NEC + P C + G+C + Y C C G+ D
Sbjct: 931 NTFSCLCLPGFTGDKCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF--DGVHCEN 986
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR--------HEPELQLCRDIDECEGETE 289
+I+EC S GG C + SF+C+CP G +E C + C
Sbjct: 987 NINEC-TESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLG 1045
Query: 290 THYIESDYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGYVLDATAQRCL 346
T+ G T L SPC N G C+ +C C G+
Sbjct: 1046 TY--RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW---------- 1093
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
+ V + C+ AA + E C G G+ G
Sbjct: 1094 ----AGAYCDVPNVSCDIAASRRGVLVEHLCQHS---GVCINAGNTHYCQCPLGYT---G 1143
Query: 407 ATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ C + +DECA S G TC + G YRC+C PG
Sbjct: 1144 SYCEEQLDECA-SNPCQHGATCSDFIGGYRCECVPG 1178
Score = 132 bits (319), Expect = 2e-30
Identities = 128/454 (28%), Positives = 182/454 (40%), Gaps = 57/454 (12%)
Query: 15 IDGGFECICKPGYESGSEGALC-RDVDECR-DNPRVCRR-GRCRNTAGSYTCLCEPGFAP 71
++G + C C GY+ GA C DVDEC N C G+C NT G++ C C G+A
Sbjct: 395 LNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
Query: 72 TAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCR 131
D++EC +D C++ G F C+C G++ ++++EC+
Sbjct: 451 PRCEM--DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCE---LEINECQSNPCVN 505
Query: 132 NGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG 188
NG+C + F+C C PGFT D C G C P G Y C G
Sbjct: 506 NGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP-NG---YECQCATG 561
Query: 189 PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD-IDECDMHQS 247
+ +I+ C P C HG C++ Y CIC+PGY +C D IDEC + S
Sbjct: 562 FTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGY---MGAICSDQIDEC--YSS 614
Query: 248 YCAG-GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD----YERGDI 302
C G+C + + C C GT + + D+C H I D Y
Sbjct: 615 PCLNDGRCIDLVNGYQCNCQPGT---SGVNCEINFDDCASNPCIHGICMDGINRYSCVCS 671
Query: 303 PPTFPTRTEL------ASPCDNG-RCINTHGGFECECELG---YVLDATAQRCLDNR--R 350
P R + ++PC G CIN GF C C G + CL N
Sbjct: 672 PGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIH 731
Query: 351 GSCWRRVVDGQCEAAAPELLL-----RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD 405
G+C + +C A + + + EC + G+ KGF
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGF---K 788
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDC 438
G C+ ++DECA S GTC + Y C C
Sbjct: 789 GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC 821
Score = 125 bits (302), Expect = 3e-28
Identities = 132/476 (27%), Positives = 190/476 (39%), Gaps = 74/476 (15%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N G C ++ G++C C+PG + G C + D+C NP C G C + Y+C+
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNP--CIHGICMDGINRYSCV 669
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG-YRPTATRGACVDVDE 123
C PGF T D+DECA++ KG C+N F+C+C G + P+ V+E
Sbjct: 670 CSPGF--TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYS----QVNE 723
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGSEL 180
C C +G C ++C C G+ N D CL G +C G
Sbjct: 724 CLSNP-CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL-VNG--- 778
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
Y C +G N +I+EC + P G+C + GY C C Y
Sbjct: 779 YRCTCKKGFKGYNCQVNIDECASNP-CLNQGTCFDDISGYTCHCVLPYTGK--------- 828
Query: 241 ECDMHQSYCAGGQCRNTA--------GSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C + C+ C N A S+TC+C G + + + DIDEC + ++
Sbjct: 829 NCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ---RCTIDIDECISKPCMNH 885
Query: 293 IESDYERG----DIPPTFPTRTE-------LASPCDNG-RCINTHGGFECECELGYVLD- 339
+G + PP F LA+PC NG C++ F C C G+ D
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDK 945
Query: 340 --ATAQRCLDN---RRGSCWRRVVDGQCEAAAPELLLR-----QECCCSVGLAWGSXXXX 389
CL G+C V C+ A + EC S G+
Sbjct: 946 CQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
Query: 390 XXXXXXXXXKGFAKLDGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPGLT 443
GF G+ C +++EC S+ C GTCV+ G+YRC CP G T
Sbjct: 1006 INSFSCLCPVGFT---GSFCLHEINEC--SSHPCLNEGTCVDGLGTYRCSCPLGYT 1056
Score = 120 bits (290), Expect = 8e-27
Identities = 93/346 (26%), Positives = 137/346 (39%), Gaps = 35/346 (10%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C NG+ GF CIC G S V+EC NP C G C Y C
Sbjct: 694 GATCINGV-----NGFRCICPEGPHHPS---CYSQVNECLSNP--CIHGNCTGGLSGYKC 743
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
LC+ G+ D +EC ++ GG C N ++C C+ G++ + V++DE
Sbjct: 744 LCDAGWVGINCE--VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ---VNIDE 798
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYA 182
C G C + + C C+ +T N + C + E Y
Sbjct: 799 CASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP-DADGLCRDIDE 241
LC G DI+EC + P HG C N + Y C C PG+ D + DID+
Sbjct: 859 CLCAPGWQGQRCTIDIDECISKP-CMNHGLCHNTQGSYMCECPPGFSGMDCE---EDIDD 914
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEGETETHYIES--- 295
C + GG C + +F+C+C P G + + ++ C G T + Y+ S
Sbjct: 915 C-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTC 973
Query: 296 ----DYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGY 336
++ TE S C NG C++ F C C +G+
Sbjct: 974 KCQAGFDGVHCENNINECTE--SSCFNGGTCVDGINSFSCLCPVGF 1017
Score = 116 bits (280), Expect = 1e-25
Identities = 121/457 (26%), Positives = 174/457 (38%), Gaps = 65/457 (14%)
Query: 7 CTNG-ICKNIDG--GFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYT 62
C N +CK + C+C PG++ G C D+DEC P + G C NT GSY
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECISKPCM-NHGLCHNTQGSYM 896
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDV 121
C C PGF+ D+D+C A+ GG C++ +F C+C G+ T C D+
Sbjct: 897 CECPPGFSGMDCE--EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF----TGDKCQTDM 950
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
+EC + G C + S+ C+C GF N+ C G +C G
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTC----VDGI 1006
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
++ LCP G + +INEC++ P G+C + YRC C GY
Sbjct: 1007 NSFSCLCPVGFTGSFCLHEINECSSHP-CLNEGTCVDGLGTYRCSCPLGYTGK------- 1058
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
C + C+ C+N TCV + + E Q C Y +
Sbjct: 1059 --NCQTLVNLCSRSPCKNKG---TCV-----QKKAESQCL-----CPSGWAGAYCDVPNV 1103
Query: 299 RGDIPPTFPTRTELASP-CDN-GRCINTHGGFECECELGYV---LDATAQRCLDN--RRG 351
DI + R L C + G CIN C+C LGY + C N + G
Sbjct: 1104 SCDIAAS--RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHG 1161
Query: 352 SCWRRVVDG-QCEAAAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD 405
+ + G +CE + EC G+ G
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR--- 1218
Query: 406 GATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C + +D+CA GG C++ G Y C C PG
Sbjct: 1219 GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPG 1255
Score = 116 bits (279), Expect = 2e-25
Identities = 121/470 (25%), Positives = 174/470 (37%), Gaps = 60/470 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGS 60
NGG+C +G+ + C C P + G C DVDEC P C+ G C N G
Sbjct: 271 NGGVCVDGV-----NTYNCRCPPQWT----GQFCTEDVDECLLQPNACQNGGTCANRNGG 321
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
Y C+C G++ ++D+CA S G C++ SF C+C P G
Sbjct: 322 YGCVCVNGWSGDDCS--ENIDDCAFASCTPGSTCIDRVASFSCMC-----PEGKAGLLCH 374
Query: 121 VDECEEQRVCRNGR-CHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACP 174
+D+ C G C P G + C C G+ + D C C
Sbjct: 375 LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCV 434
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDAD 233
+ C +G + DINEC + P C + +C + G+ C+C PG+
Sbjct: 435 NTDGAFHCE-CLKGYAGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFKGVHC 491
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
L +I+EC + GQC + F C+CP G P Q+ DID+C +
Sbjct: 492 EL--EINECQSNPC-VNNGQCVDKVNRFQCLCPPGFT-GPVCQI--DIDDCSSTPCLNGA 545
Query: 294 ES-DYERGDIPPTFPTRTEL----------ASPCDNGRCINTHGGFECECELGY---VLD 339
+ D+ G T + PC +G+C + + C C GY +
Sbjct: 546 KCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICS 605
Query: 340 ATAQRCLDN---RRGSCWRRVVDGQCE----AAAPELLLRQECCCSVGLAWGSXXXXXXX 392
C + G C V QC + + + C S G
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINR 665
Query: 393 XXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G C D+DECA S G TC+N +RC CP G
Sbjct: 666 YSCVCSPGFT---GQRCNIDIDECA-SNPCRKGATCINGVNGFRCICPEG 711
Score = 108 bits (260), Expect = 3e-23
Identities = 101/374 (27%), Positives = 151/374 (40%), Gaps = 52/374 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ F C+C PG+ G C+ D++EC P C+ G C + S
Sbjct: 922 NGGSCMDGV-----NTFSCLCLPGFT----GDKCQTDMNECLSEP--CKNGGTCSDYVNS 970
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
YTC C+ GF +C + ++EC S GG CV+ SF C+C G+ T C+
Sbjct: 971 YTCKCQAGFDGV---HCENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCL 1023
Query: 120 -DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+++EC G C + G++RC C G+T N +T + L + Q
Sbjct: 1024 HEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKN-CQTLVNLCSRSPCKNKGTCVQKK 1082
Query: 179 ELYAVLCPEG--------PSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYH 229
LCP G P+ A V C H G C N + C C GY
Sbjct: 1083 AESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY- 1141
Query: 230 PDADGLCRD-IDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECE 285
C + +DEC + G C + G + C C +G E E+ C++ C+
Sbjct: 1142 --TGSYCEEQLDECASNPCQ-HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQN-QPCQ 1197
Query: 286 GETETHYIESDYERGDIPPTFPTRTE------LASP-CDN-GRCINTHGGFECECELGYV 337
+ + ++ P T E P C N G+C++ GG+ C C G+
Sbjct: 1198 NGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA 1257
Query: 338 ---LDATAQRCLDN 348
+ CL N
Sbjct: 1258 GERCEGDINECLSN 1271
Score = 105 bits (252), Expect = 3e-22
Identities = 125/435 (28%), Positives = 162/435 (37%), Gaps = 48/435 (11%)
Query: 41 ECRDNPRVC-RRGRCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSE 98
+CRD C G C G+ C C GF YC D C + GG CV
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFL---GEYCQHRDPCEKNRCQNGGTCVAQA 83
Query: 99 --GSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNG-RCHN-TPGSFRCECLPGFTLSN 154
G C C +G+ T C R C NG CH + ++ C C GFT
Sbjct: 84 MLGKATCRCASGF--TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE 141
Query: 155 DGRT--CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG- 211
T CL G +C Q ++ C G + D+NEC +PG C HG
Sbjct: 142 CQWTDACLSHPCANGSTCTTVANQ----FSCKCLTGFTGQKCETDVNECD-IPGHCQHGG 196
Query: 212 SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAG-SFTCVC-P-- 266
+C NL Y+C C G+ G D S C GG CR T +F C C P
Sbjct: 197 TCLNLPGSYQCQCLQGF----TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGF 252
Query: 267 EGTRHEPELQ-----LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP--CDNG 319
EG+ E + C++ C T+ + T L P C NG
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNG 312
Query: 320 -RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWR------RVVDGQC---EAAAPEL 369
C N +GG+ C C G+ D ++ D SC RV C E A L
Sbjct: 313 GTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLL 372
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALS-AELCA-GGT 426
+ C S G+ GA C DVDECA++ + C G
Sbjct: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGK 432
Query: 427 CVNTDGSYRCDCPPG 441
CVNTDG++ C+C G
Sbjct: 433 CVNTDGAFHCECLKG 447
Score = 100 bits (240), Expect = 9e-21
Identities = 80/270 (29%), Positives = 112/270 (41%), Gaps = 35/270 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
+G+C N C C GY G+ C + +DEC NP C+ G C + G Y C C
Sbjct: 1123 SGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASNP--CQHGATCSDFIGGYRCECV 1176
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD--VDEC 124
PG+ Y +VDEC GG C++ F+C C P TRG + +D+C
Sbjct: 1177 PGYQGVNCEY--EVDECQNQPCQNGGTCIDLVNHFKCSC-----PPGTRGLLCEENIDDC 1229
Query: 125 EEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C N G+C + G + C CLPGF D CL S Q +
Sbjct: 1230 ARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDC--IQLTND 1287
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSC---ENLEPGYRCICDPGYHPDADGLCR 237
Y +C + + ++ C +P G+C N+ G+ C C PG+ + C+
Sbjct: 1288 YLCVCRSAFTGRHCETFVDVCPQMP-CLNGGTCAVASNMPDGFICRCPPGF---SGARCQ 1343
Query: 238 DIDECDMHQSYC-AGGQCRNTAGSFTCVCP 266
C Q C G QC +TA C CP
Sbjct: 1344 --SSCG--QVKCRKGEQCVHTASGPRCFCP 1369
Score = 93.9 bits (223), Expect = 1e-18
Identities = 79/291 (27%), Positives = 113/291 (38%), Gaps = 32/291 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA-GSY 61
NGG C + + + G C C G+ E C + G C + +Y
Sbjct: 75 NGGTC---VAQAMLGKATCRCASGFTG--EDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY 129
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VD 120
C C+ GF C D C + G C F C C G+ T C D
Sbjct: 130 ECTCQVGFTGKE---CQWTDACLSHPCANGSTCTTVANQFSCKCLTGF----TGQKCETD 182
Query: 121 VDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWG----VSCQACPA 175
V+EC+ C++G C N PGS++C+CL GFT G+ C L + V+ C
Sbjct: 183 VNECDIPGHCQHGGTCLNLPGSYQCQCLQGFT----GQYCDSLYVPCAPSPCVNGGTCRQ 238
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADG 234
G + C G +I++C C +G C + Y C C P +
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNIDDCP--NHRCQNGGVCVDGVNTYNCRCPPQW--TGQF 294
Query: 235 LCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
D+DEC + + C GG C N G + CVC G + +ID+C
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD---DCSENIDDC 342
Score = 93.5 bits (222), Expect = 1e-18
Identities = 68/232 (29%), Positives = 97/232 (41%), Gaps = 31/232 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C ++ F+C C PG + G LC + +D+C P G+C + G Y+C
Sbjct: 1196 CQNGGTCIDLVNHFKCSCPPG----TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCR 1251
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGR--CVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C PGFA D++EC ++ G C+ + CVC + + R VD
Sbjct: 1252 CLPGFAGERCE--GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF---TGRHCETFVD 1306
Query: 123 ECEEQRVCRNGRC---HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C + G C N P F C C PGF+ + +C +K G C A G
Sbjct: 1307 VCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQC-VHTASGPR 1365
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPH-GSC--ENLEPGYRCICDPGY 228
+ CP ++G C + P C H GSC + P Y C C P +
Sbjct: 1366 CF---CPSPRDCESG------CASSP--CQHGGSCHPQRQPPYYSCQCAPPF 1406
Score = 91.9 bits (218), Expect = 4e-18
Identities = 85/314 (27%), Positives = 130/314 (41%), Gaps = 42/314 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSY 61
NGG C +GI F C+C G+ G+ C +++EC +P + G C + G+Y
Sbjct: 998 NGGTCVDGI-----NSFSCLCPVGFT----GSFCLHEINECSSHPCL-NEGTCVDGLGTY 1047
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C G+ C + + S CK G CV + QC+C +G+ V
Sbjct: 1048 RCSCPLGYT---GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVS 1104
Query: 121 VDECEEQR------VCRN-GRCHNTPGSFRCECLPGFTLS---NDGRTCLGLKLGWGVSC 170
D +R +C++ G C N + C+C G+T S C G +C
Sbjct: 1105 CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATC 1164
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYH 229
Y C G N +++EC P C +G +C +L ++C C PG
Sbjct: 1165 SDFIGG----YRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPGTR 1218
Query: 230 PDADGLCRD-IDECDMHQSYCAGGQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDEC- 284
LC + ID+C GGQC + G ++C C P G R E ++ C + C
Sbjct: 1219 ---GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLS-NPCS 1274
Query: 285 -EGETETHYIESDY 297
EG + + +DY
Sbjct: 1275 SEGSLDCIQLTNDY 1288
Score = 45.2 bits (102), Expect = 5e-04
Identities = 85/352 (24%), Positives = 115/352 (32%), Gaps = 57/352 (16%)
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSNDGRTCLGL 162
C GY P G CV HN G+ C+C GF C
Sbjct: 28 CRDGYEPCVNEGMCVTY--------------HN--GTGYCKCPEGFLGEYCQHRDPCEKN 71
Query: 163 KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPG-Y 220
+ G +C A G C G + ++ + V C +G +C L Y
Sbjct: 72 RCQNGGTCVAQAMLGKA--TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY 129
Query: 221 RCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEG---TRHEPELQ 276
C C G+ C+ D C H CA G C A F+C C G + E ++
Sbjct: 130 ECTCQVGFTGKE---CQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
Query: 277 LCRDIDECEGETETHYIESDYERGDIPP-TFPTRTELASPCDNGRCINTHGGFECECELG 335
C C+ + Y+ + T L PC C+N G C
Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVN---GGTCRQTGD 241
Query: 336 YVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXX 395
+ + CL GS R +D C P + C G+
Sbjct: 242 FTFECN---CLPGFEGSTCERNID-DC----PNHRCQNGGVCVDGV------------NT 281
Query: 396 XXXKGFAKLDGATC-RDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLD 445
+ + G C DVDEC L C GGTC N +G Y C C G + D
Sbjct: 282 YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD 333
>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
Length = 2471
Score = 157 bits (380), Expect = 1e-37
Identities = 127/464 (27%), Positives = 186/464 (40%), Gaps = 51/464 (10%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N C + GGF C+C PG++ G C +++EC+ NP V G+C + + CL
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQSNPCV-NNGQCVDKVNRFQCL 519
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD-VDE 123
C PGF T D+D+C++ G +C++ ++C C G+ T C + +D
Sbjct: 520 CPPGF--TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF----TGVLCEENIDN 573
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--- 180
C+ C +G+C + S+ C C PG+ G C ++ S C G +
Sbjct: 574 CDPDP-CHHGQCQDGIDSYTCICNPGYM----GAICSD-QIDECYS-SPCLNDGRCIDLV 626
Query: 181 --YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
Y C G S N + ++C + P C HG C + Y C+C PG+ + D
Sbjct: 627 NGYQCNCQPGTSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGFTGQRCNI--D 682
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEP---ELQLCRDID----ECEGETETH 291
IDEC + G C N F C+CPEG H ++ C C G +
Sbjct: 683 IDECASNPCR-KGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGY 741
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELG---YVLDATAQRCLD 347
D I L++PC NG C N G+ C C+ G Y C
Sbjct: 742 KCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECAS 801
Query: 348 N---RRGSCWRRVVDGQCEAAAPELLLRQECC---CSVGLAWGSXXXXXXXXXXXXXKGF 401
N +G+C+ + C P + CS +
Sbjct: 802 NPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLC 861
Query: 402 AK-LDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
A G C D+DEC +S G C NT GSY C+CPPG +
Sbjct: 862 APGWQGQRCTIDIDEC-ISKPCMNHGLCHNTQGSYMCECPPGFS 904
Score = 144 bits (349), Expect = 6e-34
Identities = 130/470 (27%), Positives = 199/470 (42%), Gaps = 67/470 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + G+EC C G+ G LC + +D C +P C G+C++ SYTC+
Sbjct: 541 CLNGAKCIDHPNGYECQCATGFT----GVLCEENIDNCDPDP--CHHGQCQDGIDSYTCI 594
Query: 65 CEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PG+ C+D +DEC + GRC++ +QC C+ G T+ ++ D+
Sbjct: 595 CNPGY---MGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPG---TSGVNCEINFDD 648
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C C +G C + + C C PGFT + D C G +C G
Sbjct: 649 C-ASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC----INGVNG 703
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
+ +CPEGP + + +NEC + P C HG+C GY+C+CD G+ G+ ++D
Sbjct: 704 FRCICPEGPHHPSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW----VGINCEVD 757
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG----ETETHYIE- 294
+ + + C GG C N + C C +G + Q+ +IDEC T + +
Sbjct: 758 KNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGY-NCQV--NIDECASNPCLNQGTCFDDI 814
Query: 295 SDYERGDIPPTF--PTRTELA----SPCDNGRCINTHGGFE---CECELGY--------V 337
S Y + P +T LA +PC+N FE C C G+ +
Sbjct: 815 SGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
Query: 338 LDATAQRCLD-----NRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
+ ++ C++ N +GS G E + +C + GS
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDI--DDCLANPCQNGGSCMDGVNT 932
Query: 393 XXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G C+ D++EC LS GGTC + SY C C G
Sbjct: 933 FSCLCLPGFT---GDKCQTDMNEC-LSEPCKNGGTCSDYVNSYTCKCQAG 978
Score = 140 bits (338), Expect = 1e-32
Identities = 111/385 (28%), Positives = 164/385 (42%), Gaps = 52/385 (13%)
Query: 1 MTNGGMCTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNT 57
M N C + G C N DG F C C GY G C D++EC +P C+ C +
Sbjct: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP--CQNDATCLDK 474
Query: 58 AGSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG 116
G +TCLC PGF +C +++EC ++ G+CV+ FQC+C G+ T
Sbjct: 475 IGGFTCLCMPGFKGV---HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGP 527
Query: 117 AC-VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQA 172
C +D+D+C +C + P + C+C GFT + C G CQ
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQ- 585
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
G + Y +C G I+EC + P G C +L GY+C C PG
Sbjct: 586 ---DGIDSYTCICNPGYMGAICSDQIDECYSSP-CLNDGRCIDLVNGYQCNCQPG----T 637
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDEC------E 285
G+ +I+ D + C G C + ++CVC G Q C DIDEC +
Sbjct: 638 SGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG----QRCNIDIDECASNPCRK 693
Query: 286 GETETHYIESDY----ERGDIPPTFPTRTE-LASPCDNGRCINTHGGFECECELGYV--- 337
G T + + E P + E L++PC +G C G++C C+ G+V
Sbjct: 694 GATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGIN 753
Query: 338 LDATAQRCLDN--RRGSCWRRVVDG 360
+ CL N + G +V+G
Sbjct: 754 CEVDKNECLSNPCQNGGTCDNLVNG 778
Score = 136 bits (330), Expect = 1e-31
Identities = 128/456 (28%), Positives = 182/456 (39%), Gaps = 64/456 (14%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C N+ G+ C CK G++ G C+ ++DEC NP + +G C + YTC
Sbjct: 766 CQNGGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECASNPCL-NQGTCFDDISGYTCH 820
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGR-CVNSEG--SFQCVCEAGYRPTATRGACVDV 121
C P C V + + C+ C S S+ C+C G++ + +D+
Sbjct: 821 C---VLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQG---QRCTIDI 874
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
DEC + +G CHNT GS+ CEC PGF+ D CL G SC G
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCM----DGV 930
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
++ LC G + D D+NEC + P C + G+C + Y C C G+ D
Sbjct: 931 NTFSCLCLPGFTGDKCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF--DGVHCEN 986
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR--------HEPELQLCRDIDECEGETE 289
+I+EC S GG C + SF+C+CP G +E C + C
Sbjct: 987 NINEC-TESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLG 1045
Query: 290 THYIESDYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGYVLDATAQRCL 346
T+ G T L SPC N G C+ +C C G+
Sbjct: 1046 TY--RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW---------- 1093
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
+ V + C+ AA + E C G G+ G
Sbjct: 1094 ----AGAYCDVPNVSCDIAASRRGVLVEHLCQHS---GVCINAGNTHYCQCPLGYT---G 1143
Query: 407 ATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ C + +DECA S G TC + G YRC+C PG
Sbjct: 1144 SYCEEQLDECA-SNPCQHGATCSDFIGGYRCECVPG 1178
Score = 132 bits (319), Expect = 2e-30
Identities = 128/454 (28%), Positives = 182/454 (40%), Gaps = 57/454 (12%)
Query: 15 IDGGFECICKPGYESGSEGALC-RDVDECR-DNPRVCRR-GRCRNTAGSYTCLCEPGFAP 71
++G + C C GY+ GA C DVDEC N C G+C NT G++ C C G+A
Sbjct: 395 LNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
Query: 72 TAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCR 131
D++EC +D C++ G F C+C G++ ++++EC+
Sbjct: 451 PRCEM--DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCE---LEINECQSNPCVN 505
Query: 132 NGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG 188
NG+C + F+C C PGFT D C G C P G Y C G
Sbjct: 506 NGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP-NG---YECQCATG 561
Query: 189 PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD-IDECDMHQS 247
+ +I+ C P C HG C++ Y CIC+PGY +C D IDEC + S
Sbjct: 562 FTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGY---MGAICSDQIDEC--YSS 614
Query: 248 YCAG-GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD----YERGDI 302
C G+C + + C C GT + + D+C H I D Y
Sbjct: 615 PCLNDGRCIDLVNGYQCNCQPGT---SGVNCEINFDDCASNPCIHGICMDGINRYSCVCS 671
Query: 303 PPTFPTRTEL------ASPCDNG-RCINTHGGFECECELG---YVLDATAQRCLDNR--R 350
P R + ++PC G CIN GF C C G + CL N
Sbjct: 672 PGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIH 731
Query: 351 GSCWRRVVDGQCEAAAPELLL-----RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD 405
G+C + +C A + + + EC + G+ KGF
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGF---K 788
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDC 438
G C+ ++DECA S GTC + Y C C
Sbjct: 789 GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC 821
Score = 125 bits (302), Expect = 3e-28
Identities = 132/476 (27%), Positives = 190/476 (39%), Gaps = 74/476 (15%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N G C ++ G++C C+PG + G C + D+C NP C G C + Y+C+
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNP--CIHGICMDGINRYSCV 669
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG-YRPTATRGACVDVDE 123
C PGF T D+DECA++ KG C+N F+C+C G + P+ V+E
Sbjct: 670 CSPGF--TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYS----QVNE 723
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGSEL 180
C C +G C ++C C G+ N D CL G +C G
Sbjct: 724 CLSNP-CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL-VNG--- 778
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
Y C +G N +I+EC + P G+C + GY C C Y
Sbjct: 779 YRCTCKKGFKGYNCQVNIDECASNP-CLNQGTCFDDISGYTCHCVLPYTGK--------- 828
Query: 241 ECDMHQSYCAGGQCRNTA--------GSFTCVCPEGTRHEPELQLCRDIDECEGETETHY 292
C + C+ C N A S+TC+C G + + + DIDEC + ++
Sbjct: 829 NCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ---RCTIDIDECISKPCMNH 885
Query: 293 IESDYERG----DIPPTFPTRTE-------LASPCDNG-RCINTHGGFECECELGYVLD- 339
+G + PP F LA+PC NG C++ F C C G+ D
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDK 945
Query: 340 --ATAQRCLDN---RRGSCWRRVVDGQCEAAAPELLLR-----QECCCSVGLAWGSXXXX 389
CL G+C V C+ A + EC S G+
Sbjct: 946 CQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
Query: 390 XXXXXXXXXKGFAKLDGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPGLT 443
GF G+ C +++EC S+ C GTCV+ G+YRC CP G T
Sbjct: 1006 INSFSCLCPVGFT---GSFCLHEINEC--SSHPCLNEGTCVDGLGTYRCSCPLGYT 1056
Score = 120 bits (290), Expect = 8e-27
Identities = 93/346 (26%), Positives = 137/346 (39%), Gaps = 35/346 (10%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C NG+ GF CIC G S V+EC NP C G C Y C
Sbjct: 694 GATCINGV-----NGFRCICPEGPHHPS---CYSQVNECLSNP--CIHGNCTGGLSGYKC 743
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
LC+ G+ D +EC ++ GG C N ++C C+ G++ + V++DE
Sbjct: 744 LCDAGWVGINCE--VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ---VNIDE 798
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYA 182
C G C + + C C+ +T N + C + E Y
Sbjct: 799 CASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP-DADGLCRDIDE 241
LC G DI+EC + P HG C N + Y C C PG+ D + DID+
Sbjct: 859 CLCAPGWQGQRCTIDIDECISKP-CMNHGLCHNTQGSYMCECPPGFSGMDCE---EDIDD 914
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEGETETHYIES--- 295
C + GG C + +F+C+C P G + + ++ C G T + Y+ S
Sbjct: 915 C-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTC 973
Query: 296 ----DYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGY 336
++ TE S C NG C++ F C C +G+
Sbjct: 974 KCQAGFDGVHCENNINECTE--SSCFNGGTCVDGINSFSCLCPVGF 1017
Score = 116 bits (280), Expect = 1e-25
Identities = 121/457 (26%), Positives = 174/457 (38%), Gaps = 65/457 (14%)
Query: 7 CTNG-ICKNIDG--GFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYT 62
C N +CK + C+C PG++ G C D+DEC P + G C NT GSY
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECISKPCM-NHGLCHNTQGSYM 896
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDV 121
C C PGF+ D+D+C A+ GG C++ +F C+C G+ T C D+
Sbjct: 897 CECPPGFSGMDCE--EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF----TGDKCQTDM 950
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
+EC + G C + S+ C+C GF N+ C G +C G
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTC----VDGI 1006
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD 238
++ LCP G + +INEC++ P G+C + YRC C GY
Sbjct: 1007 NSFSCLCPVGFTGSFCLHEINECSSHP-CLNEGTCVDGLGTYRCSCPLGYTGK------- 1058
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
C + C+ C+N TCV + + E Q C Y +
Sbjct: 1059 --NCQTLVNLCSRSPCKNKG---TCV-----QKKAESQCL-----CPSGWAGAYCDVPNV 1103
Query: 299 RGDIPPTFPTRTELASP-CDN-GRCINTHGGFECECELGYV---LDATAQRCLDN--RRG 351
DI + R L C + G CIN C+C LGY + C N + G
Sbjct: 1104 SCDIAAS--RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHG 1161
Query: 352 SCWRRVVDG-QCEAAAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD 405
+ + G +CE + EC G+ G
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR--- 1218
Query: 406 GATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C + +D+CA GG C++ G Y C C PG
Sbjct: 1219 GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPG 1255
Score = 116 bits (279), Expect = 2e-25
Identities = 121/470 (25%), Positives = 174/470 (37%), Gaps = 60/470 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGS 60
NGG+C +G+ + C C P + G C DVDEC P C+ G C N G
Sbjct: 271 NGGVCVDGV-----NTYNCRCPPQWT----GQFCTEDVDECLLQPNACQNGGTCANRNGG 321
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
Y C+C G++ ++D+CA S G C++ SF C+C P G
Sbjct: 322 YGCVCVNGWSGDDCS--ENIDDCAFASCTPGSTCIDRVASFSCMC-----PEGKAGLLCH 374
Query: 121 VDECEEQRVCRNGR-CHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACP 174
+D+ C G C P G + C C G+ + D C C
Sbjct: 375 LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCV 434
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDAD 233
+ C +G + DINEC + P C + +C + G+ C+C PG+
Sbjct: 435 NTDGAFHCE-CLKGYAGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFKGVHC 491
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
L +I+EC + GQC + F C+CP G P Q+ DID+C +
Sbjct: 492 EL--EINECQSNPC-VNNGQCVDKVNRFQCLCPPGFT-GPVCQI--DIDDCSSTPCLNGA 545
Query: 294 ES-DYERGDIPPTFPTRTEL----------ASPCDNGRCINTHGGFECECELGY---VLD 339
+ D+ G T + PC +G+C + + C C GY +
Sbjct: 546 KCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICS 605
Query: 340 ATAQRCLDN---RRGSCWRRVVDGQCE----AAAPELLLRQECCCSVGLAWGSXXXXXXX 392
C + G C V QC + + + C S G
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINR 665
Query: 393 XXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G C D+DECA S G TC+N +RC CP G
Sbjct: 666 YSCVCSPGFT---GQRCNIDIDECA-SNPCRKGATCINGVNGFRCICPEG 711
Score = 108 bits (260), Expect = 3e-23
Identities = 101/374 (27%), Positives = 151/374 (40%), Gaps = 52/374 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ F C+C PG+ G C+ D++EC P C+ G C + S
Sbjct: 922 NGGSCMDGV-----NTFSCLCLPGFT----GDKCQTDMNECLSEP--CKNGGTCSDYVNS 970
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
YTC C+ GF +C + ++EC S GG CV+ SF C+C G+ T C+
Sbjct: 971 YTCKCQAGFDGV---HCENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCL 1023
Query: 120 -DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+++EC G C + G++RC C G+T N +T + L + Q
Sbjct: 1024 HEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKN-CQTLVNLCSRSPCKNKGTCVQKK 1082
Query: 179 ELYAVLCPEG--------PSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYH 229
LCP G P+ A V C H G C N + C C GY
Sbjct: 1083 AESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY- 1141
Query: 230 PDADGLCRD-IDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECE 285
C + +DEC + G C + G + C C +G E E+ C++ C+
Sbjct: 1142 --TGSYCEEQLDECASNPCQ-HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQN-QPCQ 1197
Query: 286 GETETHYIESDYERGDIPPTFPTRTE------LASP-CDN-GRCINTHGGFECECELGYV 337
+ + ++ P T E P C N G+C++ GG+ C C G+
Sbjct: 1198 NGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA 1257
Query: 338 ---LDATAQRCLDN 348
+ CL N
Sbjct: 1258 GERCEGDINECLSN 1271
Score = 106 bits (255), Expect = 1e-22
Identities = 125/435 (28%), Positives = 162/435 (37%), Gaps = 48/435 (11%)
Query: 41 ECRDNPRVC-RRGRCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSE 98
+CRD C G C G+ C C GF YC D C + GG CV
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFL---GEYCQHRDPCEKNRCQNGGTCVAQA 83
Query: 99 --GSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNG-RCHN-TPGSFRCECLPGFTLSN 154
G C C +G+ T C R C NG CH + ++ C C GFT
Sbjct: 84 MLGKATCRCASGF--TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE 141
Query: 155 DGRT--CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG- 211
T CL G +C Q ++ C G + D+NEC +PG C HG
Sbjct: 142 CQWTDACLSHPCANGSTCTTVANQ----FSCKCLTGFTGQKCETDVNECD-IPGHCQHGG 196
Query: 212 SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAG-SFTCVC-P-- 266
+C NL Y+C C G+ G D S C GG CR T +F C C P
Sbjct: 197 TCLNLPGSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGF 252
Query: 267 EGTRHEPELQ-----LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP--CDNG 319
EG+ E + C++ C T+ + T L P C NG
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNG 312
Query: 320 -RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWR------RVVDGQC---EAAAPEL 369
C N +GG+ C C G+ D ++ D SC RV C E A L
Sbjct: 313 GTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLL 372
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALS-AELCA-GGT 426
+ C S G+ GA C DVDECA++ + C G
Sbjct: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGK 432
Query: 427 CVNTDGSYRCDCPPG 441
CVNTDG++ C+C G
Sbjct: 433 CVNTDGAFHCECLKG 447
Score = 100 bits (240), Expect = 9e-21
Identities = 80/270 (29%), Positives = 112/270 (41%), Gaps = 35/270 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
+G+C N C C GY G+ C + +DEC NP C+ G C + G Y C C
Sbjct: 1123 SGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASNP--CQHGATCSDFIGGYRCECV 1176
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD--VDEC 124
PG+ Y +VDEC GG C++ F+C C P TRG + +D+C
Sbjct: 1177 PGYQGVNCEY--EVDECQNQPCQNGGTCIDLVNHFKCSC-----PPGTRGLLCEENIDDC 1229
Query: 125 EEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C N G+C + G + C CLPGF D CL S Q +
Sbjct: 1230 ARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDC--IQLTND 1287
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSC---ENLEPGYRCICDPGYHPDADGLCR 237
Y +C + + ++ C +P G+C N+ G+ C C PG+ + C+
Sbjct: 1288 YLCVCRSAFTGRHCETFVDVCPQMP-CLNGGTCAVASNMPDGFICRCPPGF---SGARCQ 1343
Query: 238 DIDECDMHQSYC-AGGQCRNTAGSFTCVCP 266
C Q C G QC +TA C CP
Sbjct: 1344 --SSCG--QVKCRKGEQCVHTASGPRCFCP 1369
Score = 93.5 bits (222), Expect = 1e-18
Identities = 68/232 (29%), Positives = 97/232 (41%), Gaps = 31/232 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C ++ F+C C PG + G LC + +D+C P G+C + G Y+C
Sbjct: 1196 CQNGGTCIDLVNHFKCSCPPG----TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCR 1251
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGR--CVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C PGFA D++EC ++ G C+ + CVC + + R VD
Sbjct: 1252 CLPGFAGERCE--GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF---TGRHCETFVD 1306
Query: 123 ECEEQRVCRNGRC---HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C + G C N P F C C PGF+ + +C +K G C A G
Sbjct: 1307 VCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQC-VHTASGPR 1365
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPH-GSC--ENLEPGYRCICDPGY 228
+ CP ++G C + P C H GSC + P Y C C P +
Sbjct: 1366 CF---CPSPRDCESG------CASSP--CQHGGSCHPQRQPPYYSCQCAPPF 1406
Score = 91.9 bits (218), Expect = 4e-18
Identities = 85/314 (27%), Positives = 130/314 (41%), Gaps = 42/314 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSY 61
NGG C +GI F C+C G+ G+ C +++EC +P + G C + G+Y
Sbjct: 998 NGGTCVDGI-----NSFSCLCPVGFT----GSFCLHEINECSSHPCL-NEGTCVDGLGTY 1047
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C G+ C + + S CK G CV + QC+C +G+ V
Sbjct: 1048 RCSCPLGYT---GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVS 1104
Query: 121 VDECEEQR------VCRN-GRCHNTPGSFRCECLPGFTLS---NDGRTCLGLKLGWGVSC 170
D +R +C++ G C N + C+C G+T S C G +C
Sbjct: 1105 CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATC 1164
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYH 229
Y C G N +++EC P C +G +C +L ++C C PG
Sbjct: 1165 SDFIGG----YRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCIDLVNHFKCSCPPGTR 1218
Query: 230 PDADGLCRD-IDECDMHQSYCAGGQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDEC- 284
LC + ID+C GGQC + G ++C C P G R E ++ C + C
Sbjct: 1219 ---GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLS-NPCS 1274
Query: 285 -EGETETHYIESDY 297
EG + + +DY
Sbjct: 1275 SEGSLDCIQLTNDY 1288
Score = 91.1 bits (216), Expect = 7e-18
Identities = 78/291 (26%), Positives = 112/291 (38%), Gaps = 32/291 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA-GSY 61
NGG C + + + G C C G+ E C + G C + +Y
Sbjct: 75 NGGTC---VAQAMLGKATCRCASGFTG--EDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY 129
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VD 120
C C+ GF C D C + G C F C C G+ T C D
Sbjct: 130 ECTCQVGFTGKE---CQWTDACLSHPCANGSTCTTVANQFSCKCLTGF----TGQKCETD 182
Query: 121 VDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWG----VSCQACPA 175
V+EC+ C++G C N PGS++C+C GFT G+ C L + V+ C
Sbjct: 183 VNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSLYVPCAPSPCVNGGTCRQ 238
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADG 234
G + C G +I++C C +G C + Y C C P +
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNIDDCP--NHRCQNGGVCVDGVNTYNCRCPPQW--TGQF 294
Query: 235 LCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
D+DEC + + C GG C N G + CVC G + +ID+C
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD---DCSENIDDC 342
Score = 60.5 bits (140), Expect = 1e-08
Identities = 97/386 (25%), Positives = 135/386 (34%), Gaps = 53/386 (13%)
Query: 70 APTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
AP A C D + C + MC G+ C C G+ C D CE+ R
Sbjct: 21 APAHALQCRDGYEPCVNEGMC----VTYHNGTGYCKCPEGFLGEY----CQHRDPCEKNR 72
Query: 129 VCRNGRC--HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ---ACPAQGSELYAV 183
G C G C C GFT D + C C + Y
Sbjct: 73 CQNGGTCVAQAMLGKATCRCASGFT-GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYEC 131
Query: 184 LCPEG-PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR-DID 240
C G K+ D C + P C +GS C + + C C G+ C D++
Sbjct: 132 TCQVGFTGKECQWTDA--CLSHP--CANGSTCTTVANQFSCKCLTGFTGQK---CETDVN 184
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEG--TRHEPELQL-CRDIDECEGETETHYIESDY 297
ECD+ GG C N GS+ C CP+G ++ L + C G T + +
Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTF 244
Query: 298 ERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRR 356
E +P + E C N RC N GG C G ++ RC G
Sbjct: 245 ECNCLPGFEGSTCERNIDDCPNHRCQN--GGV---CVDG--VNTYNCRCPPQWTGQF--- 294
Query: 357 VVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDEC 415
C E LL+ C + G+ G++ G C ++D+C
Sbjct: 295 -----CTEDVDECLLQPNACQN----GGTCANRNGGYGCVCVNGWS---GDDCSENIDDC 342
Query: 416 ALSAELCAGGTCVNTDGSYRCDCPPG 441
A A G TC++ S+ C CP G
Sbjct: 343 AF-ASCTPGSTCIDRVASFSCMCPEG 367
Score = 46.8 bits (106), Expect = 2e-04
Identities = 86/353 (24%), Positives = 116/353 (32%), Gaps = 59/353 (16%)
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSNDGRTCLGL 162
C GY P G CV HN G+ C+C GF C
Sbjct: 28 CRDGYEPCVNEGMCVTY--------------HN--GTGYCKCPEGFLGEYCQHRDPCEKN 71
Query: 163 KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPG-Y 220
+ G +C A G C G + ++ + V C +G +C L Y
Sbjct: 72 RCQNGGTCVAQAMLGKA--TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY 129
Query: 221 RCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEG---TRHEPELQ 276
C C G+ C+ D C H CA G C A F+C C G + E ++
Sbjct: 130 ECTCQVGFTGKE---CQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
Query: 277 LCRDIDECEGETETHYIESDYERGDIPPTFPTR--TELASPCDNGRCINTHGGFECECEL 334
C C+ + Y+ P F + L PC C+N G C
Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQC-QCPQGFTGQYCDSLYVPCAPSPCVN---GGTCRQTG 240
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
+ + CL GS R +D C P + C G+
Sbjct: 241 DFTFECN---CLPGFEGSTCERNID-DC----PNHRCQNGGVCVDGV------------N 280
Query: 395 XXXXKGFAKLDGATC-RDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLD 445
+ + G C DVDEC L C GGTC N +G Y C C G + D
Sbjct: 281 TYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD 333
>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
protein.
Length = 1289
Score = 156 bits (378), Expect = 2e-37
Identities = 146/456 (32%), Positives = 187/456 (41%), Gaps = 49/456 (10%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCL 64
C NG +CK+ GF C C G+ SGS L DVDEC P CR G +C + Y C
Sbjct: 481 CVNGGVCKDRVNGFSCTCPSGF-SGSTCQL--DVDECASTP--CRNGAKCVDQPDGYECR 535
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C GF T +VD+C+ D C GRCV+ SF C C GY T TR VDEC
Sbjct: 536 CAEGFEGTLCD--RNVDDCSPDP-CHHGRCVDGIASFSCACAPGY--TGTRCES-QVDEC 589
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGSELY 181
Q G+C + + C C G T N + C +GV C+ G Y
Sbjct: 590 RSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV-CR----DGINRY 644
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDE 241
+C G + +INEC + P GSC + E G+RC+C PG P LC
Sbjct: 645 DCVCQPGFTGPLCNVEINECASSPCG-EGGSCVDGENGFRCLCPPGSLPP---LCLPPSH 700
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECEGETETHYIESDYE-- 298
H+ C+ G C + G F CVC G + L RD E + SD
Sbjct: 701 PCAHEP-CSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGF 759
Query: 299 RGDIPPTFPTRT-ELASPCDNGRCINTHGGFECECELGYVLDATAQR-----CLDNRRGS 352
PP R EL SPC C HGG CE G + + + CL+ GS
Sbjct: 760 HCTCPPGVQGRQCELLSPCTPNPC--EHGG-RCESAPGQLPVCSCPQGWQDPCLNG--GS 814
Query: 353 CWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGAT 408
C V C A P + C S G+ G+ G
Sbjct: 815 CQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYG---GFH 871
Query: 409 C-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
C +D+ +C+ S+ GGTCV+ S+ C C PG T
Sbjct: 872 CEQDLPDCSPSS-CFNGGTCVDGVNSFSCLCRPGYT 906
Score = 132 bits (319), Expect = 2e-30
Identities = 132/467 (28%), Positives = 183/467 (39%), Gaps = 85/467 (18%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCR-NTAGSYT 62
G+C + + F C C G+ G C D C +P C G RC G +
Sbjct: 94 GVCQSSVVAGT-ARFSCRCPRGFR----GPDCSLPDPCLSSP--CAHGARCSVGPDGRFL 146
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C PG+ + +DVDEC C+ GG C+N+ GSF+C C AGY V
Sbjct: 147 CSCPPGYQGRSCR--SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP- 203
Query: 122 DECEEQRVCRNGRCHNTPG--SFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQ 176
C CRNG G ++ C CLPGF N + C G + G +C
Sbjct: 204 --CAPSP-CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTC----VD 256
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGL 235
G Y CP + D++EC P AC +G +C N G+ C+C G+ +
Sbjct: 257 GVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW--TGESC 314
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET--ETHYI 293
++ID+C + G C + SF C CP G LC D C E
Sbjct: 315 SQNIDDCATAVCF-HGATCHDRVASFYCACPMGKTG----LLCHLDDACVSNPCHEDAIC 369
Query: 294 ESDYERG----DIPPTFPTRT------EL---ASPCDN-GRCINTHGGFECECELGYVLD 339
+++ G PP F E A+PC++ GRC+NT G F C+C GY
Sbjct: 370 DTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY--- 426
Query: 340 ATAQRCLDNRRGSCWRRVVDGQC--EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXX 397
T RC + C + G C +A + + + C C G
Sbjct: 427 -TGPRC-ETDVNEC----LSGPCRNQATCLDRIGQFTCICMAGFT--------------- 465
Query: 398 XKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G C D+DEC S+ GG C + + C CP G +
Sbjct: 466 --------GTYCEVDIDECQ-SSPCVNGGVCKDRVNGFSCTCPSGFS 503
Score = 129 bits (311), Expect = 2e-29
Identities = 143/503 (28%), Positives = 202/503 (40%), Gaps = 97/503 (19%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C ++ + C C SG+ G C ++D+C NP C G CR+ Y C+C+PG
Sbjct: 598 GKCLDLVDKYLCRCP----SGTTGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPG 651
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
F +++ECA+ +GG CV+ E F+C+C G P C+
Sbjct: 652 FTGPLCN--VEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPL----CLPPSHPCAHE 705
Query: 129 VCRNGRCHNTPGSFRCECLPGFT-------LSND---------GRTCLGLKLGWGVSCQA 172
C +G C++ PG FRC C PG++ L+ D G TC G G C
Sbjct: 706 PCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSD--GMGFHCTC 763
Query: 173 CPAQGSELYAVLCPEGPSK-DNGGADINECTAVPG-----ACPHG---------SCENLE 217
P +L P P+ ++GG C + PG +CP G SC++
Sbjct: 764 PPGVQGRQCELLSPCTPNPCEHGG----RCESAPGQLPVCSCPQGWQDPCLNGGSCQDGV 819
Query: 218 PGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR--H-EP 273
+ C C PG+ A C RD+DEC + C G C + SFTC CP G H E
Sbjct: 820 GSFSCSCLPGF---AGPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYGGFHCEQ 874
Query: 274 ELQLCRDIDECEGETETHYIESDY---ERGDIPPTFPTRTE--LASPC-DNGRCINTHGG 327
+L C G T + S G + L+ PC G C H G
Sbjct: 875 DLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPG 934
Query: 328 FECECELGY-------VLD-ATAQRCLDNRR-----GSC-----WR-RVVDGQ---CEAA 365
F C C + ++D + Q C + R C W R+ D + C A
Sbjct: 935 FRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREA 994
Query: 366 APELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALSAELCA- 423
A ++ +R E C G G +G G+ C ++VD C A+ C
Sbjct: 995 AAQIGVRLEQLCQAG---GQCVDEDSSHYCVCPEGRT---GSHCEQEVDPCL--AQPCQH 1046
Query: 424 GGTCVNTDGSYRCDCPPGLTLDS 446
GGTC G Y C+C PG D+
Sbjct: 1047 GGTCRGYMGGYMCECLPGYNGDN 1069
Score = 125 bits (302), Expect = 3e-28
Identities = 126/455 (27%), Positives = 176/455 (38%), Gaps = 57/455 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNT--AGS 60
NGG CT + C+C PG+ G C+ D C P RG C+++ AG+
Sbjct: 54 NGGRCTQLPSREA----ACLCPPGWV----GERCQLEDPCHSGP-CAGRGVCQSSVVAGT 104
Query: 61 --YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRC-VNSEGSFQCVCEAGYRPTATRGA 117
++C C GF C+ D C + G RC V +G F C C GY+ + R
Sbjct: 105 ARFSCRCPRGFRGPD---CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS- 160
Query: 118 CVDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQAC 173
DVDEC CR+ G C NTPGSFRC+C G+T N C G +C+
Sbjct: 161 --DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCR-- 216
Query: 174 PAQGSELYAVLCPEGPSKDNGGADINECTAVPG-ACPH-GSCENLEPGYRCICDPGYHPD 231
G Y C G N ++++C PG C + G+C + Y C C P +
Sbjct: 217 -QSGDLTYDCACLPGFEGQNCEVNVDDC---PGHRCLNGGTCVDGVNTYNCQCPPEW--T 270
Query: 232 ADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
D+DEC + + C GG C NT G +CVC G E ++ID+C
Sbjct: 271 GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGE---SCSQNIDDCATAVCF 327
Query: 291 HYIESDYERGDIPPTFPT-RTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
H P +T L D+ C++ + C+ V C
Sbjct: 328 HGATCHDRVASFYCACPMGKTGLLCHLDDA-CVSNPCHEDAICDTNPVNGRAICTCPPGF 386
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
G G C+ E + C +G +G+ G C
Sbjct: 387 TG--------GACDQDVDECSIGANPCEHLGRC----VNTQGSFLCQCGRGYT---GPRC 431
Query: 410 R-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
DV+EC LS TC++ G + C C G T
Sbjct: 432 ETDVNEC-LSGPCRNQATCLDRIGQFTCICMAGFT 465
Score = 123 bits (296), Expect = 1e-27
Identities = 118/389 (30%), Positives = 153/389 (39%), Gaps = 72/389 (18%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSY 61
NGG C +G+ G F C C PG+ G C RDVDEC NP C G C + S+
Sbjct: 811 NGGSCQDGV-----GSFSCSCLPGFA----GPRCARDVDECLSNP--CGPGTCTDHVASF 859
Query: 62 TCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV- 119
TC C PG+ +C D+ +C+ S GG CV+ SF C+C GY T C
Sbjct: 860 TCTCPPGYG---GFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY----TGAHCQH 912
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
+ D C + G C FRC CL FT G C L + W S Q C G
Sbjct: 913 EADPCLSRPCLHGGVCSAAHPGFRCTCLESFT----GPQCQTL-VDW-CSRQPCQNGGRC 966
Query: 180 LYA---VLCPEGPSK---DNGGADINECTAVPGA-----C-PHGSCENLEPGYRCICDPG 227
+ LCP G S D E A G C G C + + + C+C G
Sbjct: 967 VQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG 1026
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDECEG 286
+++D C + Q GG CR G + C C G + C D+DEC
Sbjct: 1027 --RTGSHCEQEVDPC-LAQPCQHGGTCRGYMGGYMCECLPGYNGDN----CEDDVDECAS 1079
Query: 287 ETETH-----YIESDYERGDIPPTFPTRTEL-------ASPCD-------NGRCINTHGG 327
+ H + + Y P T E+ P D NG C++ GG
Sbjct: 1080 QPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGG 1139
Query: 328 FECECELGYV---LDATAQRCLDNRRGSC 353
F C C GY +A C R G+C
Sbjct: 1140 FRCTCPPGYTGLRCEADINEC---RSGAC 1165
Score = 122 bits (294), Expect = 3e-27
Identities = 132/470 (28%), Positives = 188/470 (40%), Gaps = 60/470 (12%)
Query: 6 MCTNGI-CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA---GSY 61
+C +G C + F C C G G LC D C NP C +T G
Sbjct: 325 VCFHGATCHDRVASFYCACP----MGKTGLLCHLDDACVSNP--CHEDAICDTNPVNGRA 378
Query: 62 TCLCEPGFAPTAAGYC-ADVDECAADSM-CKG-GRCVNSEGSFQCVCEAGYRPTATRGAC 118
C C PGF G C DVDEC+ + C+ GRCVN++GSF C C GY T R
Sbjct: 379 ICTCPPGFT---GGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY--TGPR-CE 432
Query: 119 VDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACP 174
DV+EC CRN C + G F C C+ GFT D C G C+
Sbjct: 433 TDVNEC-LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKD-R 490
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDAD 233
G ++ CP G S D++EC + P C +G+ C + GY C C G+
Sbjct: 491 VNG---FSCTCPSGFSGSTCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGFE---G 542
Query: 234 GLC-RDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPEL-----QLCRDIDEC 284
LC R++D+C C G+C + SF+C C GTR E ++ Q CR +C
Sbjct: 543 TLCDRNVDDCS--PDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKC 600
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGY---VLDAT 341
+ + + ++PC G C + ++C C+ G+ + +
Sbjct: 601 LDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVE 660
Query: 342 AQRCLDN---RRGSCWRRVVDGQC---EAAAPELLL-RQECCCSVGLAWGSXXXXXXXXX 394
C + GSC +C + P L L C + G
Sbjct: 661 INECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFR 720
Query: 395 XXXXKGFAKLDGATC-RDVDECALSAELC-AGGTCVNTDGSYRCDCPPGL 442
G++ G C + + A ++ C AGGTC + + C CPPG+
Sbjct: 721 CVCEPGWS---GPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 767
Score = 116 bits (278), Expect = 2e-25
Identities = 138/493 (27%), Positives = 182/493 (36%), Gaps = 106/493 (21%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLC 65
C++GIC + GGF C+C+PG+ SG + D C P CR G C + + C C
Sbjct: 707 CSHGICYDAPGGFRCVCEPGW-SGPRCSQSLARDACESQP--CRAGGTCSSDGMGFHCTC 763
Query: 66 EPG--------FAPTAAGYCADVDECAA---------------DSMCKGGRCVNSEGSFQ 102
PG +P C C + D GG C + GSF
Sbjct: 764 PPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQDPCLNGGSCQDGVGSFS 823
Query: 103 CVCEAGYR-PTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPG---FTLSNDGRT 158
C C G+ P R DVDEC C G C + SF C C PG F D
Sbjct: 824 CSCLPGFAGPRCAR----DVDECLSNP-CGPGTCTDHVASFTCTCPPGYGGFHCEQDLPD 878
Query: 159 CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLE 217
C G +C G ++ LC G + + + + C + P C HG C
Sbjct: 879 CSPSSCFNGGTC----VDGVNSFSCLCRPGYTGAHCQHEADPCLSRP--CLHGGVCSAAH 932
Query: 218 PGYRCICDPGYH-PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-------T 269
PG+RC C + P L +D C Q GG+C T G++ C+CP G
Sbjct: 933 PGFRCTCLESFTGPQCQTL---VDWCS-RQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDI 986
Query: 270 RHEP----------EL-QLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDN 318
R P L QLC+ +C E +HY R LA PC +
Sbjct: 987 RSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQH 1046
Query: 319 G-RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCC 377
G C GG+ CEC GY C D+ C + Q + +L+ R C C
Sbjct: 1047 GGTCRGYMGGYMCECLPGY----NGDNCEDD-VDECASQPC--QHGGSCIDLVARYLCSC 1099
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELCAG------GTCVNT 430
G G C + D+C L +G GTCV+
Sbjct: 1100 PPGTL-----------------------GVLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1136
Query: 431 DGSYRCDCPPGLT 443
G +RC CPPG T
Sbjct: 1137 VGGFRCTCPPGYT 1149
Score = 82.6 bits (195), Expect = 3e-15
Identities = 80/283 (28%), Positives = 105/283 (37%), Gaps = 47/283 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTCLCEP 67
G C + D C+C G G+ C ++VD C P C+ G CR G Y C C P
Sbjct: 1010 GQCVDEDSSHYCVCP----EGRTGSHCEQEVDPCLAQP--CQHGGTCRGYMGGYMCECLP 1063
Query: 68 GFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV--DEC 124
G+ C D VDECA+ GG C++ + C C P T G ++ D+C
Sbjct: 1064 GYN---GDNCEDDVDECASQPCQHGGSCIDLVARYLCSC-----PPGTLGVLCEINEDDC 1115
Query: 125 -------EEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCL--GLKLGWGVSCQA 172
R NG C + G FRC C PG+T D C C
Sbjct: 1116 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQ 1175
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG------YRCIC-D 225
P G + LC G S ++ C + P C HG PG + C C
Sbjct: 1176 DPGGG---FRCLCHAGFSGPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQ 1230
Query: 226 PGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
P + P + + R E G C+ T C CP G
Sbjct: 1231 PFWGPRCERVARSCRELQCP----VGVPCQQTPRGPRCACPPG 1269
Score = 66.9 bits (156), Expect = 1e-10
Identities = 53/165 (32%), Positives = 70/165 (42%), Gaps = 19/165 (11%)
Query: 111 PTATRGACVDVDECEEQRVCRNGRCHNTPG-SFRCECLPGFTLSN---DGRTCLGLKLGW 166
P A C+D C GRC P C C PG+ + G G
Sbjct: 39 PGAAAPPCLDGSPC-----ANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGR 93
Query: 167 GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR--CIC 224
GV CQ+ G+ ++ CP G + + C + P C HG+ ++ P R C C
Sbjct: 94 GV-CQSSVVAGTARFSCRCPRGFRGPDCSLP-DPCLSSP--CAHGARCSVGPDGRFLCSC 149
Query: 225 DPGYHPDADGLCR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
PGY + CR D+DEC + + GG C NT GSF C CP G
Sbjct: 150 PPGYQGRS---CRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAG 191
Score = 64.5 bits (150), Expect = 7e-10
Identities = 51/162 (31%), Positives = 68/162 (41%), Gaps = 22/162 (13%)
Query: 1 MTNGGMCT-NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-C-RN 56
+ +G C NG C ++ GGF C C PGY G C D++ECR R C ++
Sbjct: 1121 LDSGPRCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQD 1176
Query: 57 TAGSYTCLCEPGFAPTAAGYCADV-DECAADSMCKGGRCVNSEG-----SFQCVC-EAGY 109
G + CLC GF + C V C + GG+C S G +F C C + +
Sbjct: 1177 PGGGFRCLCHAGF---SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW 1233
Query: 110 RPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT 151
P R A C E + C TP RC C PG +
Sbjct: 1234 GPRCERVA----RSCRELQCPVGVPCQQTPRGPRCACPPGLS 1271
Score = 62.1 bits (144), Expect = 4e-09
Identities = 73/255 (28%), Positives = 100/255 (39%), Gaps = 39/255 (15%)
Query: 222 CICDPGYHPDADGLCRDIDECDMHQSYCAG-GQCRNT--AGS--FTCVCPEGTRHEPELQ 276
C+C PG+ + C+ D C H CAG G C+++ AG+ F+C CP G R P+
Sbjct: 68 CLCPPGWVGER---CQLEDPC--HSGPCAGRGVCQSSVVAGTARFSCRCPRGFRG-PD-- 119
Query: 277 LCRDIDECEGETETHYIESDYERG-----DIPPTFPTRT--------ELASPCDNG-RCI 322
C D C H PP + R+ + PC +G C+
Sbjct: 120 -CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCL 178
Query: 323 NTHGGFECECELGY---VLDATAQRCLDN--RRGSCWRRVVDGQCEAAAPELLLRQECCC 377
NT G F C+C GY + + A C + R G R+ D + A Q C
Sbjct: 179 NTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEV 238
Query: 378 SVGLAWG----SXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALSAELCA-GGTCVNTD 431
+V G + + + G C DVDEC L C GGTC NT
Sbjct: 239 NVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTL 298
Query: 432 GSYRCDCPPGLTLDS 446
G + C C G T +S
Sbjct: 299 GGHSCVCVNGWTGES 313
>Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA sequence
from clone RP3-329A5 on chromosome 6p21.1-21.33. ).
Length = 993
Score = 155 bits (377), Expect = 2e-37
Identities = 115/347 (33%), Positives = 152/347 (43%), Gaps = 57/347 (16%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDEC-RDNPRVCRRGRCRNTAGSYTCLCEP 67
+ IC+N ++CICK GY +G C+DVDEC R++ C C N G+Y C C
Sbjct: 43 DAICQNTPRSYKCICKSGYTG--DGKHCKDVDECEREDNAGCVHD-CVNIPGNYRCTCYD 99
Query: 68 GFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
GF G+ C DVDECA + CVN GS++C C G+ + + C+ EE
Sbjct: 100 GFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQ--RPEE 157
Query: 127 QRVCRNGR------CHNTP-GSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQAC----- 173
C N C TP G CEC PGF L+ + R C L G G C
Sbjct: 158 GMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQ 217
Query: 174 -PAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
P G + VL +G + I C G C C + G C C G+
Sbjct: 218 GPRCGCHIKFVLHTDGKTC------IETCAVNNGGCD-SKCHDAATGVHCTCPVGFMLQP 270
Query: 233 DG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
D C+DIDEC ++ C CRNT GSF C C +G + + C+DIDEC
Sbjct: 271 DRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDIDEC------- 322
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
++R CD+ C+NT G F+C C GY+L
Sbjct: 323 ----SFDR---------------TCDH-ICVNTPGSFQCLCHRGYLL 349
Score = 146 bits (354), Expect = 1e-34
Identities = 125/419 (29%), Positives = 169/419 (40%), Gaps = 74/419 (17%)
Query: 37 RDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVDECAA-DSMCKGGRC 94
+DVDEC + C C+NT SY C+C+ G+ +C DVDEC D+ C
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGK-HCKDVDECEREDNAGCVHDC 86
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN 154
VN G+++C C G+ C+DVDEC E C N GS+ C C GF LS+
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSD 146
Query: 155 DGRTCL-----GLKL-----GWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN-ECTA 203
+ TC+ G+ G C+ P G A C G D C
Sbjct: 147 NQHTCIQRPEEGMNCMNKNHGCAHICRETPKGG---IACECRPGFELTKNQRDCKLTCNY 203
Query: 204 VPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFT 262
G C H +C++ E G RC C + DG C I+ C ++ C +C + A
Sbjct: 204 GNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGC-DSKCHDAATGVH 259
Query: 263 CVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCI 322
C CP G +P+ + C+DID E G CD+ C
Sbjct: 260 CTCPVGFMLQPDRKTCKDID-----------ECRLNNGG--------------CDH-ICR 293
Query: 323 NTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLA 382
NT G FEC C+ GY L + C D S + R D C +C C
Sbjct: 294 NTVGSFECSCKKGYKLLINERNCQDIDECS-FDRTCDHICVNTPGSF----QCLCH---- 344
Query: 383 WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+G+ C DVDEC+++ C G C+NT GSY+C CP G
Sbjct: 345 ----------------RGYLLYGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386
Score = 118 bits (284), Expect = 4e-26
Identities = 86/285 (30%), Positives = 116/285 (40%), Gaps = 21/285 (7%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G + C C G+ +G C DVDEC + C++ C N GSY C C GF
Sbjct: 86 CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFL 144
Query: 72 TAAGY-CADVDECAADSMCKGGRCVN-----SEGSFQCVCEAGYRPTATRGACVDVDECE 125
+ + C E + M K C + +G C C G+ T + C C
Sbjct: 145 SDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLT--CN 202
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQA-CPAQGSELYAVL 184
C +T RC C F L DG+TC+ C + C + ++
Sbjct: 203 YGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCT- 261
Query: 185 CPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH-PDADGLCRDI 239
CP G P + DI+EC G C H C N + C C GY + C+DI
Sbjct: 262 CPVGFMLQPDRKT-CKDIDECRLNNGGCDH-ICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
DEC ++ C NT GSF C+C G + C D+DEC
Sbjct: 320 DECSFDRT--CDHICVNTPGSFQCLCHRGYLLY-GITHCGDVDEC 361
Score = 95.1 bits (226), Expect = 5e-19
Identities = 77/278 (27%), Positives = 110/278 (39%), Gaps = 23/278 (8%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE----CRDNPRVCRRGRCRNTA 58
NGG C C N+ G +EC C+ G+ C E C + C CR T
Sbjct: 120 NGG-CQQS-CVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH-ICRETP 176
Query: 59 -GSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
G C C PGF T + + C+ C ++E +C C +
Sbjct: 177 KGGIACECRPGFELTKNQRDCKLTCNYGNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGKT 235
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSCQACP 174
C++ C + +CH+ C C GF L D +TC + +L G C
Sbjct: 236 CIET--CAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICR 293
Query: 175 -AQGSELYAVLCPEGPS---KDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
GS + C +G + DI+EC+ C H C N ++C+C GY
Sbjct: 294 NTVGS--FECSCKKGYKLLINERNCQDIDECS-FDRTCDH-ICVNTPGSFQCLCHRGYLL 349
Query: 231 DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C D+DEC +++ C G C NT GS+ C CP G
Sbjct: 350 YGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386
Score = 92.7 bits (220), Expect = 2e-18
Identities = 70/215 (32%), Positives = 93/215 (43%), Gaps = 20/215 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C + + G C C + ++G C ++ C N C +C + A
Sbjct: 205 NGG-CQH-TCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGCD-SKCHDAATGVH 259
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C GF C D+DEC ++ C N+ GSF+C C+ GY+ C D+
Sbjct: 260 CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 122 DECEEQRVCRNGRCHNTPGSFRCEC-----LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
DEC R C + C NTPGSF+C C L G T D C + G C P
Sbjct: 320 DECSFDRTC-DHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTP-- 376
Query: 177 GSELYAVLCPEGPSKDN-GGADINE---CTAVPGA 207
GS Y CP G + + G D E C PGA
Sbjct: 377 GS--YQCTCPAGQGRLHWNGKDCTEPLKCQGSPGA 409
Score = 81.4 bits (192), Expect = 6e-15
Identities = 78/285 (27%), Positives = 110/285 (38%), Gaps = 49/285 (17%)
Query: 181 YAVLCPEGPSKDNGGA-DINECTAVPGA-CPHGSCENLEPGYRCICDPGYHPDADGL-CR 237
Y +C G + D D++EC A C H C N+ YRC C G+H DG C
Sbjct: 53 YKCICKSGYTGDGKHCKDVDECEREDNAGCVH-DCVNIPGNYRCTCYDGFHLAHDGHNCL 111
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC--RDIDECEGETETH---Y 292
D+DEC C C N GS+ C C EG C R + + H +
Sbjct: 112 DVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH 170
Query: 293 IESDYERGDIP----PTFP---TRTELASPCDNGR------CINTHGGFECECELGYVLD 339
I + +G I P F + + C+ G C +T G C C + +VL
Sbjct: 171 ICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLH 230
Query: 340 ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK 399
+ C++ +C V +G C++ + C C VG
Sbjct: 231 TDGKTCIE----TC--AVNNGGCDSKCHDAATGVHCTCPVGF------------------ 266
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+ D TC+D+DEC L+ C C NT GS+ C C G L
Sbjct: 267 -MLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKL 309
Score = 70.9 bits (166), Expect = 8e-12
Identities = 93/355 (26%), Positives = 134/355 (37%), Gaps = 58/355 (16%)
Query: 117 ACVDVDECEEQRV-CR-NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP 174
A DVDEC E C + C NTP S++C C G+T DG+ C + C
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCV 83
Query: 175 AQGSEL---YAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
+ Y C +G + G D++EC G C SC N+ Y C C G+
Sbjct: 84 HDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ-SCVNMMGSYECHCREGF 142
Query: 229 H-PDADGLCRDIDE----CDMHQSYCAGGQCRNTA-GSFTCVCPEGTRHEPELQLCRDID 282
D C E C M++++ CR T G C C G + C+ +
Sbjct: 143 FLSDNQHTCIQRPEEGMNC-MNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCK-LT 200
Query: 283 ECEGETETHYIESDYERGD---IPPTFPTRTE---LASPC--DNG----RCINTHGGFEC 330
G + D E+G F T+ C +NG +C + G C
Sbjct: 201 CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHC 260
Query: 331 ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXX 390
C +G++L + C D C R+ +G C+ + EC C
Sbjct: 261 TCPVGFMLQPDRKTCKDI--DEC--RLNNGGCDHICRNTVGSFECSCK------------ 304
Query: 391 XXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
KG+ L + C+D+DEC S + CVNT GS++C C G L
Sbjct: 305 --------KGYKLLINERNCQDIDEC--SFDRTCDHICVNTPGSFQCLCHRGYLL 349
Score = 41.9 bits (94), Expect = 0.004
Identities = 19/44 (43%), Positives = 21/44 (47%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
DG C+DVDEC CVN G+YRC C G L G
Sbjct: 64 DGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDG 107
Score = 34.3 bits (75), Expect = 0.90
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Query: 410 RDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLD 445
+DVDEC + C C NT SY+C C G T D
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGD 64
>BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein.
Length = 363
Score = 155 bits (377), Expect = 2e-37
Identities = 96/297 (32%), Positives = 139/297 (46%), Gaps = 19/297 (6%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDN--PRVCRRGRCRNTAGSYTCLCE 66
+ IC+N ++C+CKPGY+ EG C D+DEC ++ C C N G+Y C C
Sbjct: 47 DAICQNTPKSYKCLCKPGYKG--EGKQCEDIDECENDYYNGGCVH-ECINIPGNYRCTCF 103
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF G+ C DVDEC ++ CVN+ GS++C C +G+ + + C+
Sbjct: 104 DGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIH--RSN 161
Query: 126 EQRVCRNGR------CHNTP-GSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQACPAQG 177
E C N C TP G C+C PGF L+ + + C L G G +C
Sbjct: 162 EGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTD 221
Query: 178 SELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LC 236
+ + +G I C G C +C++ G RC C G+ DG C
Sbjct: 222 TGPMCGCHQKYALHSDGRTCIETCAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTC 280
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
+DI+EC ++ C CRNT GSF C C +G + + + C+DIDEC E +I
Sbjct: 281 KDINECLVNNGGC-DHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHI 336
Score = 135 bits (326), Expect = 3e-31
Identities = 89/271 (32%), Positives = 122/271 (45%), Gaps = 25/271 (9%)
Query: 29 SGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVDECAADS 87
SG G++ DVDEC + C C+NT SY CLC+PG+ C D+DEC D
Sbjct: 26 SGLPGSV--DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGK-QCEDIDECENDY 82
Query: 88 MCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCE 145
G C+N G+++C C G+ C+DVDEC++ C N GS+ C+
Sbjct: 83 YNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQ 142
Query: 146 CLPGFTL----------SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG 195
C GF L SN+G C+ G C+ P G A C G
Sbjct: 143 CHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGG---VACDCRPGFDLAQNQ 199
Query: 196 ADIN-ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQ 253
D C G C H SCE+ + G C C Y +DG C I+ C ++ C
Sbjct: 200 KDCTLTCNYGNGGCQH-SCEDTDTGPMCGCHQKYALHSDGRTC--IETCAVNNGGC-DRT 255
Query: 254 CRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C++TA C CP G +P+ + C+DI+EC
Sbjct: 256 CKDTATGVRCSCPVGFTLQPDGKTCKDINEC 286
Score = 111 bits (266), Expect = 6e-24
Identities = 82/272 (30%), Positives = 108/272 (39%), Gaps = 18/272 (6%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C NI G + C C G+ +G C DVDEC+DN C++ C N GSY
Sbjct: 84 NGG-CVHE-CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYE 140
Query: 63 CLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVN-----SEGSFQCVCEAGYRPTATRG 116
C C GF + + C + M K C + +G C C G+ +
Sbjct: 141 CQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQK 200
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
C C C +T C C + L +DGRTC+ C
Sbjct: 201 DCTLT--CNYGNGGCQHSCEDTDTGPMCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKD 258
Query: 177 GSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ CP G + G DINEC G C H C N + C C GY D
Sbjct: 259 TATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH-FCRNTVGSFECGCRKGYKLLTD 317
Query: 234 -GLCRDIDECDMHQSYCAGGQCRNTAGSFTCV 264
C+DIDEC ++ C N+ GSF C+
Sbjct: 318 ERTCQDIDECSFERT--CDHICINSPGSFQCL 347
Score = 71.7 bits (168), Expect = 5e-12
Identities = 76/286 (26%), Positives = 107/286 (37%), Gaps = 50/286 (17%)
Query: 181 YAVLCPEGPSKDNGGA-DINECTA--VPGACPHGSCENLEPGYRCICDPGYHPDADGL-C 236
Y LC G + DI+EC G C H C N+ YRC C G+ DG C
Sbjct: 57 YKCLCKPGYKGEGKQCEDIDECENDYYNGGCVH-ECINIPGNYRCTCFDGFMLAHDGHNC 115
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC--RDIDECEGETETH--- 291
D+DEC + C C N GS+ C C G C R + + H
Sbjct: 116 LDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCA 174
Query: 292 YIESDYERG----DIPPTFP---TRTELASPCDNGR------CINTHGGFECECELGYVL 338
+I + +G D P F + + C+ G C +T G C C Y L
Sbjct: 175 HICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPMCGCHQKYAL 234
Query: 339 DATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX 398
+ + C++ +C V +G C+ + C C VG
Sbjct: 235 HSDGRTCIE----TC--AVNNGGCDRTCKDTATGVRCSCPVGFT---------------- 272
Query: 399 KGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+ DG TC+D++EC ++ C C NT GS+ C C G L
Sbjct: 273 ---LQPDGKTCKDINECLVNNGGC-DHFCRNTVGSFECGCRKGYKL 314
Score = 50.8 bits (116), Expect = 1e-05
Identities = 63/250 (25%), Positives = 92/250 (36%), Gaps = 44/250 (17%)
Query: 238 DIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGET-------E 289
D+DEC C C+NT S+ C+C G ++ E + C DIDECE + E
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPG--YKGEGKQCEDIDECENDYYNGGCVHE 90
Query: 290 THYIESDYE----RGDIPPTFPTRTELASPC--DNGRC----INTHGGFECECELGYVLD 339
I +Y G + C +NG C +N G +EC+C G+ L
Sbjct: 91 CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLS 150
Query: 340 ATAQRCLD---------NRRGSC---WRRVVDG--QCEAAAPELLLRQECCCSVGLAWGS 385
C+ N+ C R G C+ L + + C++ +G+
Sbjct: 151 DNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGN 210
Query: 386 XXXXXXXXXXXXX-------KGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
K DG TC ++ CA++ C TC +T RC C
Sbjct: 211 GGCQHSCEDTDTGPMCGCHQKYALHSDGRTC--IETCAVNNGGC-DRTCKDTATGVRCSC 267
Query: 439 PPGLTLDSTG 448
P G TL G
Sbjct: 268 PVGFTLQPDG 277
>AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and
EGF-like domain containing protein 3 protein.
Length = 993
Score = 155 bits (377), Expect = 2e-37
Identities = 115/347 (33%), Positives = 152/347 (43%), Gaps = 57/347 (16%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDEC-RDNPRVCRRGRCRNTAGSYTCLCEP 67
+ IC+N ++CICK GY +G C+DVDEC R++ C C N G+Y C C
Sbjct: 43 DAICQNTPRSYKCICKSGYTG--DGKHCKDVDECEREDNAGCVHD-CVNIPGNYRCTCYD 99
Query: 68 GFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
GF G+ C DVDECA + CVN GS++C C G+ + + C+ EE
Sbjct: 100 GFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQ--RPEE 157
Query: 127 QRVCRNGR------CHNTP-GSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQAC----- 173
C N C TP G CEC PGF L+ + R C L G G C
Sbjct: 158 GMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQ 217
Query: 174 -PAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
P G + VL +G + I C G C C + G C C G+
Sbjct: 218 GPRCGCHIKFVLHTDGKTC------IETCAVNNGGCD-SKCHDAATGVHCTCPVGFMLQP 270
Query: 233 DG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
D C+DIDEC ++ C CRNT GSF C C +G + + C+DIDEC
Sbjct: 271 DRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDIDEC------- 322
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
++R CD+ C+NT G F+C C GY+L
Sbjct: 323 ----SFDR---------------TCDH-ICVNTPGSFQCLCHRGYLL 349
Score = 146 bits (354), Expect = 1e-34
Identities = 125/419 (29%), Positives = 169/419 (40%), Gaps = 74/419 (17%)
Query: 37 RDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVDECAA-DSMCKGGRC 94
+DVDEC + C C+NT SY C+C+ G+ +C DVDEC D+ C
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGK-HCKDVDECEREDNAGCVHDC 86
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN 154
VN G+++C C G+ C+DVDEC E C N GS+ C C GF LS+
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSD 146
Query: 155 DGRTCL-----GLKL-----GWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN-ECTA 203
+ TC+ G+ G C+ P G A C G D C
Sbjct: 147 NQHTCIQRPEEGMNCMNKNHGCAHICRETPKGG---IACECRPGFELTKNQRDCKLTCNY 203
Query: 204 VPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFT 262
G C H +C++ E G RC C + DG C I+ C ++ C +C + A
Sbjct: 204 GNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGC-DSKCHDAATGVH 259
Query: 263 CVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCI 322
C CP G +P+ + C+DID E G CD+ C
Sbjct: 260 CTCPVGFMLQPDRKTCKDID-----------ECRLNNGG--------------CDH-ICR 293
Query: 323 NTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLA 382
NT G FEC C+ GY L + C D S + R D C +C C
Sbjct: 294 NTVGSFECSCKKGYKLLINERNCQDIDECS-FDRTCDHICVNTPGSF----QCLCH---- 344
Query: 383 WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+G+ C DVDEC+++ C G C+NT GSY+C CP G
Sbjct: 345 ----------------RGYLLYGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386
Score = 118 bits (284), Expect = 4e-26
Identities = 86/285 (30%), Positives = 116/285 (40%), Gaps = 21/285 (7%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G + C C G+ +G C DVDEC + C++ C N GSY C C GF
Sbjct: 86 CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFL 144
Query: 72 TAAGY-CADVDECAADSMCKGGRCVN-----SEGSFQCVCEAGYRPTATRGACVDVDECE 125
+ + C E + M K C + +G C C G+ T + C C
Sbjct: 145 SDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLT--CN 202
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQA-CPAQGSELYAVL 184
C +T RC C F L DG+TC+ C + C + ++
Sbjct: 203 YGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCT- 261
Query: 185 CPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH-PDADGLCRDI 239
CP G P + DI+EC G C H C N + C C GY + C+DI
Sbjct: 262 CPVGFMLQPDRKT-CKDIDECRLNNGGCDH-ICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
DEC ++ C NT GSF C+C G + C D+DEC
Sbjct: 320 DECSFDRT--CDHICVNTPGSFQCLCHRGYLLY-GITHCGDVDEC 361
Score = 95.1 bits (226), Expect = 5e-19
Identities = 77/278 (27%), Positives = 110/278 (39%), Gaps = 23/278 (8%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE----CRDNPRVCRRGRCRNTA 58
NGG C C N+ G +EC C+ G+ C E C + C CR T
Sbjct: 120 NGG-CQQS-CVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH-ICRETP 176
Query: 59 -GSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
G C C PGF T + + C+ C ++E +C C +
Sbjct: 177 KGGIACECRPGFELTKNQRDCKLTCNYGNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGKT 235
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSCQACP 174
C++ C + +CH+ C C GF L D +TC + +L G C
Sbjct: 236 CIET--CAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICR 293
Query: 175 -AQGSELYAVLCPEGPS---KDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
GS + C +G + DI+EC+ C H C N ++C+C GY
Sbjct: 294 NTVGS--FECSCKKGYKLLINERNCQDIDECS-FDRTCDH-ICVNTPGSFQCLCHRGYLL 349
Query: 231 DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C D+DEC +++ C G C NT GS+ C CP G
Sbjct: 350 YGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386
Score = 92.7 bits (220), Expect = 2e-18
Identities = 70/215 (32%), Positives = 93/215 (43%), Gaps = 20/215 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C + + G C C + ++G C ++ C N C +C + A
Sbjct: 205 NGG-CQH-TCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGCD-SKCHDAATGVH 259
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C GF C D+DEC ++ C N+ GSF+C C+ GY+ C D+
Sbjct: 260 CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 122 DECEEQRVCRNGRCHNTPGSFRCEC-----LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
DEC R C + C NTPGSF+C C L G T D C + G C P
Sbjct: 320 DECSFDRTC-DHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTP-- 376
Query: 177 GSELYAVLCPEGPSKDN-GGADINE---CTAVPGA 207
GS Y CP G + + G D E C PGA
Sbjct: 377 GS--YQCTCPAGQGRLHWNGKDCTEPLKCQGSPGA 409
Score = 81.4 bits (192), Expect = 6e-15
Identities = 78/285 (27%), Positives = 110/285 (38%), Gaps = 49/285 (17%)
Query: 181 YAVLCPEGPSKDNGGA-DINECTAVPGA-CPHGSCENLEPGYRCICDPGYHPDADGL-CR 237
Y +C G + D D++EC A C H C N+ YRC C G+H DG C
Sbjct: 53 YKCICKSGYTGDGKHCKDVDECEREDNAGCVH-DCVNIPGNYRCTCYDGFHLAHDGHNCL 111
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC--RDIDECEGETETH---Y 292
D+DEC C C N GS+ C C EG C R + + H +
Sbjct: 112 DVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH 170
Query: 293 IESDYERGDIP----PTFP---TRTELASPCDNGR------CINTHGGFECECELGYVLD 339
I + +G I P F + + C+ G C +T G C C + +VL
Sbjct: 171 ICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLH 230
Query: 340 ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK 399
+ C++ +C V +G C++ + C C VG
Sbjct: 231 TDGKTCIE----TC--AVNNGGCDSKCHDAATGVHCTCPVGF------------------ 266
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+ D TC+D+DEC L+ C C NT GS+ C C G L
Sbjct: 267 -MLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKL 309
Score = 70.9 bits (166), Expect = 8e-12
Identities = 93/355 (26%), Positives = 134/355 (37%), Gaps = 58/355 (16%)
Query: 117 ACVDVDECEEQRV-CR-NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP 174
A DVDEC E C + C NTP S++C C G+T DG+ C + C
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCV 83
Query: 175 AQGSEL---YAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
+ Y C +G + G D++EC G C SC N+ Y C C G+
Sbjct: 84 HDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ-SCVNMMGSYECHCREGF 142
Query: 229 H-PDADGLCRDIDE----CDMHQSYCAGGQCRNTA-GSFTCVCPEGTRHEPELQLCRDID 282
D C E C M++++ CR T G C C G + C+ +
Sbjct: 143 FLSDNQHTCIQRPEEGMNC-MNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCK-LT 200
Query: 283 ECEGETETHYIESDYERGD---IPPTFPTRTE---LASPC--DNG----RCINTHGGFEC 330
G + D E+G F T+ C +NG +C + G C
Sbjct: 201 CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHC 260
Query: 331 ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXX 390
C +G++L + C D C R+ +G C+ + EC C
Sbjct: 261 TCPVGFMLQPDRKTCKDI--DEC--RLNNGGCDHICRNTVGSFECSCK------------ 304
Query: 391 XXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
KG+ L + C+D+DEC S + CVNT GS++C C G L
Sbjct: 305 --------KGYKLLINERNCQDIDEC--SFDRTCDHICVNTPGSFQCLCHRGYLL 349
Score = 41.9 bits (94), Expect = 0.004
Identities = 19/44 (43%), Positives = 21/44 (47%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
DG C+DVDEC CVN G+YRC C G L G
Sbjct: 64 DGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDG 107
Score = 34.3 bits (75), Expect = 0.90
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Query: 410 RDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLD 445
+DVDEC + C C NT SY+C C G T D
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGD 64
>AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing
protein protein.
Length = 993
Score = 155 bits (377), Expect = 2e-37
Identities = 115/347 (33%), Positives = 152/347 (43%), Gaps = 57/347 (16%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDEC-RDNPRVCRRGRCRNTAGSYTCLCEP 67
+ IC+N ++CICK GY +G C+DVDEC R++ C C N G+Y C C
Sbjct: 43 DAICQNTPRSYKCICKSGYTG--DGKHCKDVDECEREDNAGCVHD-CVNIPGNYRCTCYD 99
Query: 68 GFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
GF G+ C DVDECA + CVN GS++C C G+ + + C+ EE
Sbjct: 100 GFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQ--RPEE 157
Query: 127 QRVCRNGR------CHNTP-GSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQAC----- 173
C N C TP G CEC PGF L+ + R C L G G C
Sbjct: 158 GMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQ 217
Query: 174 -PAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
P G + VL +G + I C G C C + G C C G+
Sbjct: 218 GPRCGCHIKFVLHTDGKTC------IETCAVNNGGCD-SKCHDAATGVHCTCPVGFMLQP 270
Query: 233 DG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
D C+DIDEC ++ C CRNT GSF C C +G + + C+DIDEC
Sbjct: 271 DRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDIDEC------- 322
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
++R CD+ C+NT G F+C C GY+L
Sbjct: 323 ----SFDR---------------TCDH-ICVNTPGSFQCLCHRGYLL 349
Score = 146 bits (354), Expect = 1e-34
Identities = 125/419 (29%), Positives = 169/419 (40%), Gaps = 74/419 (17%)
Query: 37 RDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVDECAA-DSMCKGGRC 94
+DVDEC + C C+NT SY C+C+ G+ +C DVDEC D+ C
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGK-HCKDVDECEREDNAGCVHDC 86
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN 154
VN G+++C C G+ C+DVDEC E C N GS+ C C GF LS+
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSD 146
Query: 155 DGRTCL-----GLKL-----GWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN-ECTA 203
+ TC+ G+ G C+ P G A C G D C
Sbjct: 147 NQHTCIQRPEEGMNCMNKNHGCAHICRETPKGG---IACECRPGFELTKNQRDCKLTCNY 203
Query: 204 VPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFT 262
G C H +C++ E G RC C + DG C I+ C ++ C +C + A
Sbjct: 204 GNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGC-DSKCHDAATGVH 259
Query: 263 CVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCI 322
C CP G +P+ + C+DID E G CD+ C
Sbjct: 260 CTCPVGFMLQPDRKTCKDID-----------ECRLNNGG--------------CDH-ICR 293
Query: 323 NTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLA 382
NT G FEC C+ GY L + C D S + R D C +C C
Sbjct: 294 NTVGSFECSCKKGYKLLINERNCQDIDECS-FDRTCDHICVNTPGSF----QCLCH---- 344
Query: 383 WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+G+ C DVDEC+++ C G C+NT GSY+C CP G
Sbjct: 345 ----------------RGYLLYGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386
Score = 118 bits (284), Expect = 4e-26
Identities = 86/285 (30%), Positives = 116/285 (40%), Gaps = 21/285 (7%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G + C C G+ +G C DVDEC + C++ C N GSY C C GF
Sbjct: 86 CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFL 144
Query: 72 TAAGY-CADVDECAADSMCKGGRCVN-----SEGSFQCVCEAGYRPTATRGACVDVDECE 125
+ + C E + M K C + +G C C G+ T + C C
Sbjct: 145 SDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLT--CN 202
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQA-CPAQGSELYAVL 184
C +T RC C F L DG+TC+ C + C + ++
Sbjct: 203 YGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCT- 261
Query: 185 CPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH-PDADGLCRDI 239
CP G P + DI+EC G C H C N + C C GY + C+DI
Sbjct: 262 CPVGFMLQPDRKT-CKDIDECRLNNGGCDH-ICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
DEC ++ C NT GSF C+C G + C D+DEC
Sbjct: 320 DECSFDRT--CDHICVNTPGSFQCLCHRGYLLY-GITHCGDVDEC 361
Score = 95.1 bits (226), Expect = 5e-19
Identities = 77/278 (27%), Positives = 110/278 (39%), Gaps = 23/278 (8%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE----CRDNPRVCRRGRCRNTA 58
NGG C C N+ G +EC C+ G+ C E C + C CR T
Sbjct: 120 NGG-CQQS-CVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH-ICRETP 176
Query: 59 -GSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
G C C PGF T + + C+ C ++E +C C +
Sbjct: 177 KGGIACECRPGFELTKNQRDCKLTCNYGNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGKT 235
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSCQACP 174
C++ C + +CH+ C C GF L D +TC + +L G C
Sbjct: 236 CIET--CAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICR 293
Query: 175 -AQGSELYAVLCPEGPS---KDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
GS + C +G + DI+EC+ C H C N ++C+C GY
Sbjct: 294 NTVGS--FECSCKKGYKLLINERNCQDIDECS-FDRTCDH-ICVNTPGSFQCLCHRGYLL 349
Query: 231 DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C D+DEC +++ C G C NT GS+ C CP G
Sbjct: 350 YGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386
Score = 92.7 bits (220), Expect = 2e-18
Identities = 70/215 (32%), Positives = 93/215 (43%), Gaps = 20/215 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C + + G C C + ++G C ++ C N C +C + A
Sbjct: 205 NGG-CQH-TCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGCD-SKCHDAATGVH 259
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C GF C D+DEC ++ C N+ GSF+C C+ GY+ C D+
Sbjct: 260 CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 122 DECEEQRVCRNGRCHNTPGSFRCEC-----LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
DEC R C + C NTPGSF+C C L G T D C + G C P
Sbjct: 320 DECSFDRTC-DHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTP-- 376
Query: 177 GSELYAVLCPEGPSKDN-GGADINE---CTAVPGA 207
GS Y CP G + + G D E C PGA
Sbjct: 377 GS--YQCTCPAGQGRLHWNGKDCTEPLKCQGSPGA 409
Score = 81.4 bits (192), Expect = 6e-15
Identities = 78/285 (27%), Positives = 110/285 (38%), Gaps = 49/285 (17%)
Query: 181 YAVLCPEGPSKDNGGA-DINECTAVPGA-CPHGSCENLEPGYRCICDPGYHPDADGL-CR 237
Y +C G + D D++EC A C H C N+ YRC C G+H DG C
Sbjct: 53 YKCICKSGYTGDGKHCKDVDECEREDNAGCVH-DCVNIPGNYRCTCYDGFHLAHDGHNCL 111
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC--RDIDECEGETETH---Y 292
D+DEC C C N GS+ C C EG C R + + H +
Sbjct: 112 DVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH 170
Query: 293 IESDYERGDIP----PTFP---TRTELASPCDNGR------CINTHGGFECECELGYVLD 339
I + +G I P F + + C+ G C +T G C C + +VL
Sbjct: 171 ICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLH 230
Query: 340 ATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK 399
+ C++ +C V +G C++ + C C VG
Sbjct: 231 TDGKTCIE----TC--AVNNGGCDSKCHDAATGVHCTCPVGF------------------ 266
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+ D TC+D+DEC L+ C C NT GS+ C C G L
Sbjct: 267 -MLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKL 309
Score = 70.9 bits (166), Expect = 8e-12
Identities = 93/355 (26%), Positives = 134/355 (37%), Gaps = 58/355 (16%)
Query: 117 ACVDVDECEEQRV-CR-NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP 174
A DVDEC E C + C NTP S++C C G+T DG+ C + C
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCV 83
Query: 175 AQGSEL---YAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
+ Y C +G + G D++EC G C SC N+ Y C C G+
Sbjct: 84 HDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ-SCVNMMGSYECHCREGF 142
Query: 229 H-PDADGLCRDIDE----CDMHQSYCAGGQCRNTA-GSFTCVCPEGTRHEPELQLCRDID 282
D C E C M++++ CR T G C C G + C+ +
Sbjct: 143 FLSDNQHTCIQRPEEGMNC-MNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCK-LT 200
Query: 283 ECEGETETHYIESDYERGD---IPPTFPTRTE---LASPC--DNG----RCINTHGGFEC 330
G + D E+G F T+ C +NG +C + G C
Sbjct: 201 CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHC 260
Query: 331 ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXX 390
C +G++L + C D C R+ +G C+ + EC C
Sbjct: 261 TCPVGFMLQPDRKTCKDI--DEC--RLNNGGCDHICRNTVGSFECSCK------------ 304
Query: 391 XXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
KG+ L + C+D+DEC S + CVNT GS++C C G L
Sbjct: 305 --------KGYKLLINERNCQDIDEC--SFDRTCDHICVNTPGSFQCLCHRGYLL 349
Score = 41.9 bits (94), Expect = 0.004
Identities = 19/44 (43%), Positives = 21/44 (47%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
DG C+DVDEC CVN G+YRC C G L G
Sbjct: 64 DGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDG 107
Score = 34.3 bits (75), Expect = 0.90
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Query: 410 RDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLD 445
+DVDEC + C C NT SY+C C G T D
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGD 64
>BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB
domain, EGF-like 3 protein.
Length = 992
Score = 154 bits (374), Expect = 5e-37
Identities = 113/344 (32%), Positives = 151/344 (43%), Gaps = 52/344 (15%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDEC-RDNPRVCRRGRCRNTAGSYTCLCEP 67
+ IC+N ++CICK GY +G C+DVDEC R++ C C N G+Y C C
Sbjct: 43 DAICQNTPRSYKCICKSGYTG--DGKHCKDVDECEREDNAGCVHD-CVNIPGNYRCTCYD 99
Query: 68 GFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE--- 123
GF G+ C DVDECA + CVN GS++C C G+ + + C+ E
Sbjct: 100 GFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEGMN 159
Query: 124 CEEQRVCRNGRCHNTP-GSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQAC------PA 175
C + C TP G CEC PGF L+ + R C L G G C P
Sbjct: 160 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPR 219
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG- 234
G + VL +G + I C G C C + G C C G+ D
Sbjct: 220 CGCHIKFVLHTDGKTC------IETCAVNNGGCD-SKCHDAAIGVHCTCPVGFMLQPDRK 272
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
C+DIDEC ++ C CRNT GSF C C +G + + C+DIDEC
Sbjct: 273 TCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQDIDEC---------- 321
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
++R CD+ C+NT G F+C C GY+L
Sbjct: 322 -SFDR---------------TCDH-ICVNTPGSFQCLCHRGYLL 348
Score = 146 bits (354), Expect = 1e-34
Identities = 125/418 (29%), Positives = 169/418 (40%), Gaps = 73/418 (17%)
Query: 37 RDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVDECAA-DSMCKGGRC 94
+DVDEC + C C+NT SY C+C+ G+ +C DVDEC D+ C
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGK-HCKDVDECEREDNAGCVHDC 86
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN 154
VN G+++C C G+ C+DVDEC E C N GS+ C C GF LS+
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSD 146
Query: 155 DGRTCL----GLKL-----GWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN-ECTAV 204
+ TC+ G+ G C+ P G A C G D C
Sbjct: 147 NQHTCIQRPEGMNCMNKNHGCAHICRETPKGG---IACECRPGFELTKNQRDCKLTCNYG 203
Query: 205 PGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
G C H +C++ E G RC C + DG C I+ C ++ C +C + A C
Sbjct: 204 NGGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGC-DSKCHDAAIGVHC 259
Query: 264 VCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCIN 323
CP G +P+ + C+DID E G CD+ C N
Sbjct: 260 TCPVGFMLQPDRKTCKDID-----------ECRLNNGG--------------CDH-ICRN 293
Query: 324 THGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAW 383
T G FEC C+ GY L + C D S + R D C +C C
Sbjct: 294 TVGSFECSCKKGYKLLINERNCQDIDECS-FDRTCDHICVNTPGSF----QCLCH----- 343
Query: 384 GSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+G+ C DVDEC+++ C G C+NT GSY+C CP G
Sbjct: 344 ---------------RGYLLYGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 385
Score = 114 bits (274), Expect = 7e-25
Identities = 83/283 (29%), Positives = 111/283 (39%), Gaps = 18/283 (6%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G + C C G+ +G C DVDEC + C++ C N GSY C C GF
Sbjct: 86 CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFL 144
Query: 72 TAAGYCADVDECAADSMCKGGRCVN-----SEGSFQCVCEAGYRPTATRGACVDVDECEE 126
+ + + M K C + +G C C G+ T + C C
Sbjct: 145 SDNQHTCIQRPEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLT--CNY 202
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCP 186
C +T RC C F L DG+TC+ C + + CP
Sbjct: 203 GNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAAIGVHCTCP 262
Query: 187 EG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH-PDADGLCRDIDE 241
G P + DI+EC G C H C N + C C GY + C+DIDE
Sbjct: 263 VGFMLQPDRKT-CKDIDECRLNNGGCDH-ICRNTVGSFECSCKKGYKLLINERNCQDIDE 320
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C ++ C NT GSF C+C G + C D+DEC
Sbjct: 321 CSFDRT--CDHICVNTPGSFQCLCHRGYLLY-GITHCGDVDEC 360
Score = 95.1 bits (226), Expect = 5e-19
Identities = 77/277 (27%), Positives = 110/277 (39%), Gaps = 22/277 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE---CRDNPRVCRRGRCRNTA- 58
NGG C C N+ G +EC C+ G+ C E C + C CR T
Sbjct: 120 NGG-CQQS-CVNMMGSYECHCREGFFLSDNQHTCIQRPEGMNCMNKNHGCAH-ICRETPK 176
Query: 59 GSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC 118
G C C PGF T + + C+ C ++E +C C + C
Sbjct: 177 GGIACECRPGFELTKNQRDCKLTCNYGNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTC 235
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSCQACP- 174
++ C + +CH+ C C GF L D +TC + +L G C
Sbjct: 236 IET--CAVNNGGCDSKCHDAAIGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRN 293
Query: 175 AQGSELYAVLCPEGPS---KDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
GS + C +G + DI+EC+ C H C N ++C+C GY
Sbjct: 294 TVGS--FECSCKKGYKLLINERNCQDIDECS-FDRTCDH-ICVNTPGSFQCLCHRGYLLY 349
Query: 232 ADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C D+DEC +++ C G C NT GS+ C CP G
Sbjct: 350 GITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 385
Score = 91.9 bits (218), Expect = 4e-18
Identities = 70/215 (32%), Positives = 93/215 (43%), Gaps = 20/215 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C + + G C C + ++G C ++ C N C +C + A
Sbjct: 204 NGG-CQH-TCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGCD-SKCHDAAIGVH 258
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C GF C D+DEC ++ C N+ GSF+C C+ GY+ C D+
Sbjct: 259 CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 318
Query: 122 DECEEQRVCRNGRCHNTPGSFRCEC-----LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
DEC R C + C NTPGSF+C C L G T D C + G C P
Sbjct: 319 DECSFDRTC-DHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTP-- 375
Query: 177 GSELYAVLCPEGPSKDN-GGADINE---CTAVPGA 207
GS Y CP G + + G D E C PGA
Sbjct: 376 GS--YQCTCPAGQGRLHWNGKDCTEPLKCQGSPGA 408
Score = 83.0 bits (196), Expect = 2e-15
Identities = 78/284 (27%), Positives = 110/284 (38%), Gaps = 48/284 (16%)
Query: 181 YAVLCPEGPSKDNGGA-DINECTAVPGA-CPHGSCENLEPGYRCICDPGYHPDADGL-CR 237
Y +C G + D D++EC A C H C N+ YRC C G+H DG C
Sbjct: 53 YKCICKSGYTGDGKHCKDVDECEREDNAGCVH-DCVNIPGNYRCTCYDGFHLAHDGHNCL 111
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDE---CEGETE-THYI 293
D+DEC C C N GS+ C C EG C E C + +I
Sbjct: 112 DVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLSDNQHTCIQRPEGMNCMNKNHGCAHI 170
Query: 294 ESDYERGDIP----PTFP---TRTELASPCDNGR------CINTHGGFECECELGYVLDA 340
+ +G I P F + + C+ G C +T G C C + +VL
Sbjct: 171 CRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHT 230
Query: 341 TAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKG 400
+ C++ +C V +G C++ + + C C VG
Sbjct: 231 DGKTCIE----TC--AVNNGGCDSKCHDAAIGVHCTCPVGF------------------- 265
Query: 401 FAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+ D TC+D+DEC L+ C C NT GS+ C C G L
Sbjct: 266 MLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKL 308
Score = 41.9 bits (94), Expect = 0.004
Identities = 19/44 (43%), Positives = 21/44 (47%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
DG C+DVDEC CVN G+YRC C G L G
Sbjct: 64 DGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDG 107
Score = 34.3 bits (75), Expect = 0.90
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Query: 410 RDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLD 445
+DVDEC + C C NT SY+C C G T D
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGD 64
>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 153 bits (370), Expect = 2e-36
Identities = 98/295 (33%), Positives = 129/295 (43%), Gaps = 18/295 (6%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
T+ G C + C N G + C CKPG+ ++ C ++ C C+ + T +
Sbjct: 62 THNGGCQHR-CVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH 120
Query: 62 TCLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C PGF G +C CA + RC G +C C GY+ A AC D
Sbjct: 121 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 180
Query: 121 VDECEEQRV-CRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQA----CPA 175
VDEC C +G C NT GSF+C C G+ L DGR C +++ SC+A C
Sbjct: 181 VDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH 239
Query: 176 QGSELYA---VLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
S A CP G D D+++C P C C N GY C C GY
Sbjct: 240 GCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYR 297
Query: 230 PDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDE 283
ADG C D+DEC + C C N AGSF C C G R + + C ++E
Sbjct: 298 LSADGCGCEDVDECASSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 351
Score = 126 bits (303), Expect = 2e-28
Identities = 128/450 (28%), Positives = 170/450 (37%), Gaps = 65/450 (14%)
Query: 17 GGFEC-ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAA 74
G + C + + GY S G DVDECR + C+ RC NT GSY C C+PGF T +
Sbjct: 35 GCYPCHLGQAGYPV-SAGDQRPDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDS 92
Query: 75 GYCADVDECAADSMCKGGRCVN-SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNG 133
C ++ CA + CV + +C C G++ CV C +
Sbjct: 93 RTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH 152
Query: 134 RCHNTPGSFRCECLPGFTLSNDGRTCLGLK---LGWGVSCQAC-PAQGSELYAVLCPEGP 189
RC G RCEC G+ L+ DG+ C + G C QGS + +C G
Sbjct: 153 RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGS--FKCVCHAGY 210
Query: 190 SKDNGGAD--------INECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDID 240
G +N C A G C HG C + G C C GY D D C D+D
Sbjct: 211 ELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVD 269
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERG 300
+C S C C N G + C C G R + C D+DEC RG
Sbjct: 270 DCA--DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECAS-----------SRG 316
Query: 301 DIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDG 360
C++ C N G F+C CE GY L + C +DG
Sbjct: 317 G--------------CEH-HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMV---DLDG 358
Query: 361 QCEAAAP---ELLLRQEC--CCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDEC 415
+ P +L+ E + F LD + D C
Sbjct: 359 ELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHD---C 415
Query: 416 ALSAELCA-GGTC-VNTDGSYRCDCPPGLT 443
+L+ + C GGTC + DG CDCP G T
Sbjct: 416 SLTCDDCRNGGTCLLGLDG---CDCPEGWT 442
Score = 125 bits (301), Expect = 4e-28
Identities = 117/365 (32%), Positives = 143/365 (39%), Gaps = 61/365 (16%)
Query: 99 GSFQC-VCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGR 157
G + C + +AGY P + DVDEC RC NTPGS+ CEC PGF L D R
Sbjct: 35 GCYPCHLGQAGY-PVSAGDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSR 93
Query: 158 TCLGLK---LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADI---NECTAVPGACPHG 211
TCL + LG G C + C G G + C G+C H
Sbjct: 94 TCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH- 152
Query: 212 SCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR 270
C+ + RC C GY ADG C D+DEC + CA G C NT GSF CVC G
Sbjct: 153 RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYE 211
Query: 271 HEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFEC 330
+ + C I E E I + E + C +G C +T G C
Sbjct: 212 LGADGRQCYRI-----EME---IVNSCEANN------------GGCSHG-CSHTSAGPLC 250
Query: 331 ECELGYVLDATAQRCLDNRRGSCWRRVVDGQC-EAAAPELLLRQECCCSVGLAWGSXXXX 389
C GY LD + C+D C D C + EC C G +
Sbjct: 251 TCPRGYELDTDQRTCIDV--DDC----ADSPCCQQVCTNNPGGYECGCYAGYRLSA---- 300
Query: 390 XXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL--DST 447
DG C DVDECA S C C N GS++C C G L D
Sbjct: 301 ---------------DGCGCEDVDECASSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRR 344
Query: 448 GTAPL 452
G +PL
Sbjct: 345 GCSPL 349
Score = 70.1 bits (164), Expect = 1e-11
Identities = 120/470 (25%), Positives = 165/470 (35%), Gaps = 92/470 (19%)
Query: 3 NGGMCTN--GICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGS 60
NGG C + G C+ G C+ G G G CR C + RGRC G+
Sbjct: 467 NGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCAN------RGRCHRLYGA 520
Query: 61 YTCLCEPG----FAPTAAGYCADVDECAADSMC---KGGRCVNSEGSFQCVCEAGYRPTA 113
CLC+PG F A C+ + C C +GS C C+AG+R
Sbjct: 521 --CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS--CSCKAGFRGER 576
Query: 114 TRGAC---VDVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTC-LGLKLGWGV 168
+ C C + C G C + G C GF + G+ C +G +GV
Sbjct: 577 CQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGT---FGV 633
Query: 169 SC-QACPAQGSELYAVL----CPEGPSKDNGGADINE------CTAVPGACPHGSCENLE 217
+C +C G+ + V CP G + ++ AD E C + AC H + + E
Sbjct: 634 NCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPE 693
Query: 218 PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL 277
G C+C PG+ C+D+ + G C+ C C P
Sbjct: 694 TG-ACLCLPGF---VGSRCQDVCPAGWY-----GPSCQT-----RCSCANDGHCHPATGH 739
Query: 278 CRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFE-----CEC 332
C C + + G P + + PC+ C HG + C C
Sbjct: 740 C----SCAPGWTGFSCQRACDTGHWGP------DCSHPCN---CSAGHGSCDAISGLCLC 786
Query: 333 ELGYVLDATAQRCLDNRRG-SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
E GYV Q+C G C +R QC+ A + C C G W
Sbjct: 787 EAGYVGPRCEQQCPQGHFGPGCEQRC---QCQHGAACDHVSGACTCPAG--WRGTFCEHA 841
Query: 392 XXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF LD CR C AG C +GS C CP G
Sbjct: 842 CPA-----GFFGLD---CRSACNCT------AGAACDAVNGS--CLCPAG 875
Score = 46.0 bits (104), Expect = 3e-04
Identities = 67/247 (27%), Positives = 90/247 (36%), Gaps = 39/247 (15%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY---- 61
C +G C ++ G C C G+ G C CR C TAG+
Sbjct: 814 CQHGAACDHVSGA--CTCPAGWR----GTFCEHACPAGFFGLDCRSA-CNCTAGAACDAV 866
Query: 62 --TCLCEPGF-APTAAGYCADVDE---CAADSMC-KGGRCVNSEGSFQCVCEAGYRPTAT 114
+CLC G P A C D C C GG C G +C+C AG+
Sbjct: 867 NGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKC 924
Query: 115 RGACVDV---DECEEQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-S 169
+ C+ + C ++ C G CH+ G+ C C PGFT S + C + G G
Sbjct: 925 QSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQGCPPGRYGPGCEQ 982
Query: 170 CQACPAQGS---ELYAVLCPEGPSKDN------GGADINECTAVPGACPHGSCENLEPGY 220
C GS A CP G + G CT V G +C+ +
Sbjct: 983 LCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG-- 1040
Query: 221 RCICDPG 227
C+C PG
Sbjct: 1041 TCLCPPG 1047
Score = 41.5 bits (93), Expect = 0.006
Identities = 80/293 (27%), Positives = 102/293 (34%), Gaps = 52/293 (17%)
Query: 9 NGIC-KNIDGGFECI-CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
+G C K GF+ C G+ G C C P G+CR G CE
Sbjct: 606 SGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCE 665
Query: 67 PGFAPTAAGY-CADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACVDV--- 121
G C ++ C A C+ RC G+ C+C G+ + + C
Sbjct: 666 ADCPEGRWGLGCQEI--CPA---CQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYG 718
Query: 122 DECEEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG-WGVSCQ---ACPAQ 176
C+ + C N G CH P + C C PG+T + R C G WG C C A
Sbjct: 719 PSCQTRCSCANDGHCH--PATGHCSCAPGWTGFSCQRAC---DTGHWGPDCSHPCNCSAG 773
Query: 177 GSELYAV----LCPEG----------PSKDNGGADINECTAVPG-ACPH--GSCENLEPG 219
A+ LC G P G C G AC H G+C G
Sbjct: 774 HGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGAC-TCPAG 832
Query: 220 YR-CICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR 270
+R C+ GL CR C AG C GS C+CP G R
Sbjct: 833 WRGTFCEHACPAGFFGLDCRSACNC------TAGAACDAVNGS--CLCPAGRR 877
>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 153 bits (370), Expect = 2e-36
Identities = 98/295 (33%), Positives = 129/295 (43%), Gaps = 18/295 (6%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
T+ G C + C N G + C CKPG+ ++ C ++ C C+ + T +
Sbjct: 62 THNGGCQHR-CVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH 120
Query: 62 TCLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C PGF G +C CA + RC G +C C GY+ A AC D
Sbjct: 121 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 180
Query: 121 VDECEEQRV-CRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQA----CPA 175
VDEC C +G C NT GSF+C C G+ L DGR C +++ SC+A C
Sbjct: 181 VDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH 239
Query: 176 QGSELYA---VLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
S A CP G D D+++C P C C N GY C C GY
Sbjct: 240 GCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYR 297
Query: 230 PDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDE 283
ADG C D+DEC + C C N AGSF C C G R + + C ++E
Sbjct: 298 LSADGCGCEDVDECASSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 351
Score = 126 bits (303), Expect = 2e-28
Identities = 128/450 (28%), Positives = 170/450 (37%), Gaps = 65/450 (14%)
Query: 17 GGFEC-ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAA 74
G + C + + GY S G DVDECR + C+ RC NT GSY C C+PGF T +
Sbjct: 35 GCYPCHLGQAGYPV-SAGDQRPDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDS 92
Query: 75 GYCADVDECAADSMCKGGRCVN-SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNG 133
C ++ CA + CV + +C C G++ CV C +
Sbjct: 93 RTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH 152
Query: 134 RCHNTPGSFRCECLPGFTLSNDGRTCLGLK---LGWGVSCQAC-PAQGSELYAVLCPEGP 189
RC G RCEC G+ L+ DG+ C + G C QGS + +C G
Sbjct: 153 RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGS--FKCVCHAGY 210
Query: 190 SKDNGGAD--------INECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDID 240
G +N C A G C HG C + G C C GY D D C D+D
Sbjct: 211 ELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVD 269
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERG 300
+C S C C N G + C C G R + C D+DEC RG
Sbjct: 270 DCA--DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECAS-----------SRG 316
Query: 301 DIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDG 360
C++ C N G F+C CE GY L + C +DG
Sbjct: 317 G--------------CEH-HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMV---DLDG 358
Query: 361 QCEAAAP---ELLLRQEC--CCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDEC 415
+ P +L+ E + F LD + D C
Sbjct: 359 ELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHD---C 415
Query: 416 ALSAELCA-GGTC-VNTDGSYRCDCPPGLT 443
+L+ + C GGTC + DG CDCP G T
Sbjct: 416 SLTCDDCRNGGTCLLGLDG---CDCPEGWT 442
Score = 125 bits (301), Expect = 4e-28
Identities = 117/365 (32%), Positives = 143/365 (39%), Gaps = 61/365 (16%)
Query: 99 GSFQC-VCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGR 157
G + C + +AGY P + DVDEC RC NTPGS+ CEC PGF L D R
Sbjct: 35 GCYPCHLGQAGY-PVSAGDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSR 93
Query: 158 TCLGLK---LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADI---NECTAVPGACPHG 211
TCL + LG G C + C G G + C G+C H
Sbjct: 94 TCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH- 152
Query: 212 SCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR 270
C+ + RC C GY ADG C D+DEC + CA G C NT GSF CVC G
Sbjct: 153 RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYE 211
Query: 271 HEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFEC 330
+ + C I E E I + E + C +G C +T G C
Sbjct: 212 LGADGRQCYRI-----EME---IVNSCEANN------------GGCSHG-CSHTSAGPLC 250
Query: 331 ECELGYVLDATAQRCLDNRRGSCWRRVVDGQC-EAAAPELLLRQECCCSVGLAWGSXXXX 389
C GY LD + C+D C D C + EC C G +
Sbjct: 251 TCPRGYELDTDQRTCIDV--DDC----ADSPCCQQVCTNNPGGYECGCYAGYRLSA---- 300
Query: 390 XXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL--DST 447
DG C DVDECA S C C N GS++C C G L D
Sbjct: 301 ---------------DGCGCEDVDECASSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRR 344
Query: 448 GTAPL 452
G +PL
Sbjct: 345 GCSPL 349
Score = 70.1 bits (164), Expect = 1e-11
Identities = 120/470 (25%), Positives = 165/470 (35%), Gaps = 92/470 (19%)
Query: 3 NGGMCTN--GICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGS 60
NGG C + G C+ G C+ G G G CR C + RGRC G+
Sbjct: 467 NGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCAN------RGRCHRLYGA 520
Query: 61 YTCLCEPG----FAPTAAGYCADVDECAADSMC---KGGRCVNSEGSFQCVCEAGYRPTA 113
CLC+PG F A C+ + C C +GS C C+AG+R
Sbjct: 521 --CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS--CSCKAGFRGER 576
Query: 114 TRGAC---VDVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTC-LGLKLGWGV 168
+ C C + C G C + G C GF + G+ C +G +GV
Sbjct: 577 CQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGT---FGV 633
Query: 169 SC-QACPAQGSELYAVL----CPEGPSKDNGGADINE------CTAVPGACPHGSCENLE 217
+C +C G+ + V CP G + ++ AD E C + AC H + + E
Sbjct: 634 NCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPE 693
Query: 218 PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL 277
G C+C PG+ C+D+ + G C+ C C P
Sbjct: 694 TG-ACLCLPGF---VGSRCQDVCPAGWY-----GPSCQT-----RCSCANDGHCHPATGH 739
Query: 278 CRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFE-----CEC 332
C C + + G P + + PC+ C HG + C C
Sbjct: 740 C----SCAPGWTGFSCQRACDTGHWGP------DCSHPCN---CSAGHGSCDAISGLCLC 786
Query: 333 ELGYVLDATAQRCLDNRRG-SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
E GYV Q+C G C +R QC+ A + C C G W
Sbjct: 787 EAGYVGPRCEQQCPQGHFGPGCEQRC---QCQHGAACDHVSGACTCPAG--WRGTFCEHA 841
Query: 392 XXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF LD CR C AG C +GS C CP G
Sbjct: 842 CPA-----GFFGLD---CRSACNCT------AGAACDAVNGS--CLCPAG 875
Score = 46.0 bits (104), Expect = 3e-04
Identities = 67/247 (27%), Positives = 90/247 (36%), Gaps = 39/247 (15%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY---- 61
C +G C ++ G C C G+ G C CR C TAG+
Sbjct: 814 CQHGAACDHVSGA--CTCPAGWR----GTFCEHACPAGFFGLDCRSA-CNCTAGAACDAV 866
Query: 62 --TCLCEPGF-APTAAGYCADVDE---CAADSMC-KGGRCVNSEGSFQCVCEAGYRPTAT 114
+CLC G P A C D C C GG C G +C+C AG+
Sbjct: 867 NGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKC 924
Query: 115 RGACVDV---DECEEQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-S 169
+ C+ + C ++ C G CH+ G+ C C PGFT S + C + G G
Sbjct: 925 QSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQGCPPGRYGPGCEQ 982
Query: 170 CQACPAQGS---ELYAVLCPEGPSKDN------GGADINECTAVPGACPHGSCENLEPGY 220
C GS A CP G + G CT V G +C+ +
Sbjct: 983 LCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG-- 1040
Query: 221 RCICDPG 227
C+C PG
Sbjct: 1041 TCLCPPG 1047
Score = 41.5 bits (93), Expect = 0.006
Identities = 80/293 (27%), Positives = 102/293 (34%), Gaps = 52/293 (17%)
Query: 9 NGIC-KNIDGGFECI-CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
+G C K GF+ C G+ G C C P G+CR G CE
Sbjct: 606 SGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCE 665
Query: 67 PGFAPTAAGY-CADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACVDV--- 121
G C ++ C A C+ RC G+ C+C G+ + + C
Sbjct: 666 ADCPEGRWGLGCQEI--CPA---CQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYG 718
Query: 122 DECEEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG-WGVSCQ---ACPAQ 176
C+ + C N G CH P + C C PG+T + R C G WG C C A
Sbjct: 719 PSCQTRCSCANDGHCH--PATGHCSCAPGWTGFSCQRAC---DTGHWGPDCSHPCNCSAG 773
Query: 177 GSELYAV----LCPEG----------PSKDNGGADINECTAVPG-ACPH--GSCENLEPG 219
A+ LC G P G C G AC H G+C G
Sbjct: 774 HGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGAC-TCPAG 832
Query: 220 YR-CICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR 270
+R C+ GL CR C AG C GS C+CP G R
Sbjct: 833 WRGTFCEHACPAGFFGLDCRSACNC------TAGAACDAVNGS--CLCPAGRR 877
>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
protein.
Length = 1640
Score = 153 bits (370), Expect = 2e-36
Identities = 98/295 (33%), Positives = 129/295 (43%), Gaps = 18/295 (6%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
T+ G C + C N G + C CKPG+ ++ C ++ C C+ + T +
Sbjct: 242 THNGGCQHR-CVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH 300
Query: 62 TCLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C PGF G +C CA + RC G +C C GY+ A AC D
Sbjct: 301 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 360
Query: 121 VDECEEQRV-CRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQA----CPA 175
VDEC C +G C NT GSF+C C G+ L DGR C +++ SC+A C
Sbjct: 361 VDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH 419
Query: 176 QGSELYA---VLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
S A CP G D D+++C P C C N GY C C GY
Sbjct: 420 GCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYR 477
Query: 230 PDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDE 283
ADG C D+DEC + C C N AGSF C C G R + + C ++E
Sbjct: 478 LSADGCGCEDVDECASSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 531
Score = 134 bits (324), Expect = 6e-31
Identities = 125/382 (32%), Positives = 151/382 (39%), Gaps = 65/382 (17%)
Query: 82 ECAADSMCKGGRCVNSEGSFQ-CVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
EC+A GGRCV GS Q C C G++ + DVDEC RC NTPG
Sbjct: 202 ECSAGLCFHGGRCV--PGSAQPCHCPPGFQGPRCQ---YDVDECRTHNGGCQHRCVNTPG 256
Query: 141 SFRCECLPGFTLSNDGRTCLGLK---LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGAD 197
S+ CEC PGF L D RTCL + LG G C + C G G
Sbjct: 257 SYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRH 316
Query: 198 I---NECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQ 253
+ C G+C H C+ + RC C GY ADG C D+DEC + CA G
Sbjct: 317 CVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG- 374
Query: 254 CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELA 313
C NT GSF CVC G + + C I E E I + E +
Sbjct: 375 CLNTQGSFKCVCHAGYELGADGRQCYRI-----EME---IVNSCEANN------------ 414
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQC-EAAAPELLLR 372
C +G C +T G C C GY LD + C+D C D C +
Sbjct: 415 GGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDV--DDC----ADSPCCQQVCTNNPGG 467
Query: 373 QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDG 432
EC C G + DG C DVDECA S C C N G
Sbjct: 468 YECGCYAGYRLSA-------------------DGCGCEDVDECASSRGGCE-HHCTNLAG 507
Query: 433 SYRCDCPPGLTL--DSTGTAPL 452
S++C C G L D G +PL
Sbjct: 508 SFQCSCEAGYRLHEDRRGCSPL 529
Score = 134 bits (324), Expect = 6e-31
Identities = 132/465 (28%), Positives = 180/465 (38%), Gaps = 70/465 (15%)
Query: 3 NGGMCTNGICKNIDGGFE-CICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS 60
+ G+C +G + + G + C C PG++ G C+ DVDECR + C+ RC NT GS
Sbjct: 204 SAGLCFHG-GRCVPGSAQPCHCPPGFQ----GPRCQYDVDECRTHNGGCQH-RCVNTPGS 257
Query: 61 YTCLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVN-SEGSFQCVCEAGYRPTATRGAC 118
Y C C+PGF T + C ++ CA + CV + +C C G++ C
Sbjct: 258 YLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 317
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK---LGWGVSCQAC-P 174
V C + RC G RCEC G+ L+ DG+ C + G C
Sbjct: 318 VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLN 377
Query: 175 AQGSELYAVLCPEGPSKDNGGAD--------INECTAVPGACPHGSCENLEPGYRCICDP 226
QGS + +C G G +N C A G C HG C + G C C
Sbjct: 378 TQGS--FKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPR 434
Query: 227 GYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
GY D D C D+D+C S C C N G + C C G R + C D+DEC
Sbjct: 435 GYELDTDQRTCIDVDDCA--DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECA 492
Query: 286 GETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
RG C++ C N G F+C CE GY L + C
Sbjct: 493 S-----------SRGG--------------CEH-HCTNLAGSFQCSCEAGYRLHEDRRGC 526
Query: 346 LDNRRGSCWRRVVDGQCEAAAP---ELLLRQEC--CCSVGLAWGSXXXXXXXXXXXXXKG 400
+DG+ P +L+ E +
Sbjct: 527 SPLEEPMV---DLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEK 583
Query: 401 FAKLDGATCRDVDECALSAELCA-GGTC-VNTDGSYRCDCPPGLT 443
F LD + D C+L+ + C GGTC + DG CDCP G T
Sbjct: 584 FVCLDDSFGHD---CSLTCDDCRNGGTCLLGLDG---CDCPEGWT 622
Score = 68.9 bits (161), Expect = 3e-11
Identities = 118/469 (25%), Positives = 164/469 (34%), Gaps = 90/469 (19%)
Query: 3 NGGMCTN--GICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGS 60
NGG C + G C+ G C+ G G G CR C + RGRC G+
Sbjct: 647 NGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCAN------RGRCHRLYGA 700
Query: 61 YTCLCEPG----FAPTAAGYCADVDECAADSMC---KGGRCVNSEGSFQCVCEAGYRPTA 113
CLC+PG F A C+ + C C +GS C C+AG+R
Sbjct: 701 --CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS--CSCKAGFRGER 756
Query: 114 TRGAC---VDVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTC-LGLKLGWGV 168
+ C C + C G C + G C GF + G+ C +G +GV
Sbjct: 757 CQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGT---FGV 813
Query: 169 SC-QACPAQGSELYAVL----CPEGPSKDNGGADINE------CTAVPGACPHGSCENLE 217
+C +C G+ + V CP G + ++ AD E C + AC H + + E
Sbjct: 814 NCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPE 873
Query: 218 PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL 277
G C+C PG+ C+D+ + G C+ C C P
Sbjct: 874 TG-ACLCLPGF---VGSRCQDVCPAGWY-----GPSCQT-----RCSCANDGHCHPATGH 919
Query: 278 CRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFE-----CEC 332
C C + + G P + + PC+ C HG + C C
Sbjct: 920 C----SCAPGWTGFSCQRACDTGHWGP------DCSHPCN---CSAGHGSCDAISGLCLC 966
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
E GYV Q+C G ++ QC+ A + C C G W
Sbjct: 967 EAGYVGPRCEQQCPQGHFGPGCEQLC--QCQHGAACDHVSGACTCPAG--WRGTFCEHAC 1022
Query: 393 XXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF LD CR C AG C +GS C CP G
Sbjct: 1023 PA-----GFFGLD---CRSACNCT------AGAACDAVNGS--CLCPAG 1055
Score = 65.3 bits (152), Expect = 4e-10
Identities = 76/276 (27%), Positives = 101/276 (36%), Gaps = 50/276 (18%)
Query: 192 DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCA 250
D G EC+A G C HG C C PG+ C+ D+DEC H C
Sbjct: 194 DEEGCLSAECSA--GLCFHGGRCVPGSAQPCHCPPGFQGPR---CQYDVDECRTHNGGCQ 248
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC---EGETETHYIESDYERG--DIPPT 305
+C NT GS+ C C G R + + C I+ C G + H ++ R P
Sbjct: 249 H-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPG 307
Query: 306 FPTRTE-----LASPCDN--GRCIN----THGGFECECELGYVLDATAQRCLDNRRGSCW 354
F + + SPC N G C++ G CEC +GY L A + C D C
Sbjct: 308 FQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED--VDECA 365
Query: 355 RRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVD- 413
+ QC +C C G G+ DG C ++
Sbjct: 366 AGL--AQCAHGCLNTQGSFKCVCHAGYELGA-------------------DGRQCYRIEM 404
Query: 414 ECALSAELCAGGT---CVNTDGSYRCDCPPGLTLDS 446
E S E GG C +T C CP G LD+
Sbjct: 405 EIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDT 440
Score = 50.8 bits (116), Expect = 1e-05
Identities = 57/203 (28%), Positives = 71/203 (34%), Gaps = 14/203 (6%)
Query: 3 NGGMC--TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR--RGRCRNTA 58
NGG+C +NG C G C+ G GA C C +N C G CR
Sbjct: 1384 NGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNS-TCEPATGTCRCGP 1442
Query: 59 GSYTCLCEPGFAPTAAGY-CADVDECAADSMCK--GGRCVNSEGSFQCVCEAGYRPTATR 115
G Y CE P G C + C + C GRC+ G CE G P +
Sbjct: 1443 GFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFG 1502
Query: 116 GACVDVDECEEQRVCR--NGRCHNTPGSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQA 172
C +C+ C G C PG C G +C L G G C
Sbjct: 1503 EGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCD- 1561
Query: 173 CPAQGSELYAVLCPEGPSKDNGG 195
P G + + V GP+ GG
Sbjct: 1562 -PVSG-QCHCVDGYMGPTCREGG 1582
Score = 50.0 bits (114), Expect = 2e-05
Identities = 89/368 (24%), Positives = 124/368 (33%), Gaps = 46/368 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDV---DECRDNPRVCRRGRCRNTAG 59
+GG G+C G C+C G+ + C + C C + G
Sbjct: 1163 SGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTG 1220
Query: 60 SYTCLCEPGFAPTAAGYCADV----DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATR 115
+ C C PGF + ++CA C G + C C AGY + +
Sbjct: 1221 A--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQ 1278
Query: 116 GACVD---VDECEEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ 171
C CE+ C N G C G+ C C GF ++ TC + G +
Sbjct: 1279 QRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHV 1336
Query: 172 ACPAQGSELYAV----LCPEGPS--KDNGGADINECTAVPGACPHG-SCENLEPGYRCIC 224
QG+ V LCP G + + G N C H SC N G C
Sbjct: 1337 CGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGV---GCEHTCSCRN---GGLCHA 1390
Query: 225 DPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
G + GL C++ C G+ A C C + EP CR
Sbjct: 1391 SNG--SCSCGLGWTGRHCEL---ACPPGR-YGAACHLECSCHNNSTCEPATGTCRCGPGF 1444
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELASPCD--NGRCI---NTHGGFECE--CELGYV 337
G+ H + + +PCD +GRC+ HG F CE CE G
Sbjct: 1445 YGQACEHPCPPGFHGAGCQGL--CWCQHGAPCDPISGRCLCPAGFHGHF-CERGCEPGSF 1501
Query: 338 LDATAQRC 345
+ QRC
Sbjct: 1502 GEGCHQRC 1509
Score = 46.8 bits (106), Expect = 2e-04
Identities = 100/388 (25%), Positives = 127/388 (32%), Gaps = 67/388 (17%)
Query: 9 NGICKNIDGGFECICKPGY---------ESGSEGALCRDVDECRDNPRVCR-RGRCRNTA 58
+G C I G C+C+ GY G G C + +C+ G C A
Sbjct: 954 HGSCDAISG--LCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPA 1011
Query: 59 GSYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
G CE G C C A + C VN GS C+C AG R
Sbjct: 1012 GWRGTFCEHACPAGFFGLDCRSACNCTAGAACDA---VN--GS--CLCPAGRRGPRCAET 1064
Query: 118 C---VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP 174
C C + C NG + P +C C PG+ G +CL QACP
Sbjct: 1065 CPAHTYGHNCSQACACFNGASCD-PVHGQCHCAPGWM----GPSCL----------QACP 1109
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPG--ACPHGSCENLEPGYRCIC-DPGYHPD 231
A LY C NGG C V G ACP G L C+ D
Sbjct: 1110 AG---LYGDNCRHSCLCQNGGT----CDPVSGHCACPEGWA-GLACEKECLPRDVRAGCR 1161
Query: 232 ADGLCRDIDECDMHQSYC------AGGQCRNTA--GSFTCVCPEGTRHEPELQLCRDIDE 283
G C + CD H C G +C++ G F C + P
Sbjct: 1162 HSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGA 1221
Query: 284 CEGETETHYIESDYERGDIPPTFPTRTELASPC--DNGRCINTHGGFECECELGYVLDAT 341
C + S E+ P +F C +N C G C C GY +
Sbjct: 1222 CR--CPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATG--TCSCAAGYHGPSC 1277
Query: 342 AQRCLDNRRGSCWRRVV----DGQCEAA 365
QRC R G ++ G C+AA
Sbjct: 1278 QQRCPPGRYGPGCEQLCGCLNGGSCDAA 1305
Score = 41.1 bits (92), Expect = 0.008
Identities = 75/289 (25%), Positives = 103/289 (35%), Gaps = 44/289 (15%)
Query: 9 NGIC-KNIDGGFECI-CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
+G C K GF+ C G+ G C C P G+CR G CE
Sbjct: 786 SGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCE 845
Query: 67 PGFAPTAAGY-CADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACVDV--- 121
G C ++ C A C+ RC G+ C+C G+ + + C
Sbjct: 846 ADCPEGRWGLGCQEI--CPA---CQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYG 898
Query: 122 DECEEQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG-WGVSCQ---ACPAQ 176
C+ + C N G CH P + C C PG+T + R C G WG C C A
Sbjct: 899 PSCQTRCSCANDGHCH--PATGHCSCAPGWTGFSCQRAC---DTGHWGPDCSHPCNCSAG 953
Query: 177 GSELYAV----LCPEGPSKDNGGADINECTAVPGA-----CPHG-SCENLEPGYRCICDP 226
A+ LC G + PG C HG +C+++ C C
Sbjct: 954 HGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGA--CTCPA 1011
Query: 227 GYHPD-ADGLCR----DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR 270
G+ + C +D C + AG C GS C+CP G R
Sbjct: 1012 GWRGTFCEHACPAGFFGLD-CRSACNCTAGAACDAVNGS--CLCPAGRR 1057
>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
Length = 1246
Score = 153 bits (370), Expect = 2e-36
Identities = 98/295 (33%), Positives = 129/295 (43%), Gaps = 18/295 (6%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
T+ G C + C N G + C CKPG+ ++ C ++ C C+ + T +
Sbjct: 79 THNGGCQHR-CVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH 137
Query: 62 TCLCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
C C PGF G +C CA + RC G +C C GY+ A AC D
Sbjct: 138 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 197
Query: 121 VDECEEQRV-CRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQA----CPA 175
VDEC C +G C NT GSF+C C G+ L DGR C +++ SC+A C
Sbjct: 198 VDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH 256
Query: 176 QGSELYA---VLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
S A CP G D D+++C P C C N GY C C GY
Sbjct: 257 GCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYR 314
Query: 230 PDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDE 283
ADG C D+DEC + C C N AGSF C C G R + + C ++E
Sbjct: 315 LSADGCGCEDVDECASSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 368
Score = 126 bits (303), Expect = 2e-28
Identities = 128/450 (28%), Positives = 170/450 (37%), Gaps = 65/450 (14%)
Query: 17 GGFEC-ICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAA 74
G + C + + GY S G DVDECR + C+ RC NT GSY C C+PGF T +
Sbjct: 52 GCYPCHLGQAGYPV-SAGDQRPDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDS 109
Query: 75 GYCADVDECAADSMCKGGRCVN-SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNG 133
C ++ CA + CV + +C C G++ CV C +
Sbjct: 110 RTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH 169
Query: 134 RCHNTPGSFRCECLPGFTLSNDGRTCLGLK---LGWGVSCQAC-PAQGSELYAVLCPEGP 189
RC G RCEC G+ L+ DG+ C + G C QGS + +C G
Sbjct: 170 RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGS--FKCVCHAGY 227
Query: 190 SKDNGGAD--------INECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDID 240
G +N C A G C HG C + G C C GY D D C D+D
Sbjct: 228 ELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVD 286
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERG 300
+C S C C N G + C C G R + C D+DEC RG
Sbjct: 287 DCA--DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECAS-----------SRG 333
Query: 301 DIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDG 360
C++ C N G F+C CE GY L + C +DG
Sbjct: 334 G--------------CEH-HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMV---DLDG 375
Query: 361 QCEAAAP---ELLLRQEC--CCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDEC 415
+ P +L+ E + F LD + D C
Sbjct: 376 ELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHD---C 432
Query: 416 ALSAELCA-GGTC-VNTDGSYRCDCPPGLT 443
+L+ + C GGTC + DG CDCP G T
Sbjct: 433 SLTCDDCRNGGTCLLGLDG---CDCPEGWT 459
Score = 125 bits (301), Expect = 4e-28
Identities = 117/365 (32%), Positives = 143/365 (39%), Gaps = 61/365 (16%)
Query: 99 GSFQC-VCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGR 157
G + C + +AGY P + DVDEC RC NTPGS+ CEC PGF L D R
Sbjct: 52 GCYPCHLGQAGY-PVSAGDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSR 110
Query: 158 TCLGLK---LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADI---NECTAVPGACPHG 211
TCL + LG G C + C G G + C G+C H
Sbjct: 111 TCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH- 169
Query: 212 SCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR 270
C+ + RC C GY ADG C D+DEC + CA G C NT GSF CVC G
Sbjct: 170 RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYE 228
Query: 271 HEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFEC 330
+ + C I E E I + E + C +G C +T G C
Sbjct: 229 LGADGRQCYRI-----EME---IVNSCEANN------------GGCSHG-CSHTSAGPLC 267
Query: 331 ECELGYVLDATAQRCLDNRRGSCWRRVVDGQC-EAAAPELLLRQECCCSVGLAWGSXXXX 389
C GY LD + C+D C D C + EC C G +
Sbjct: 268 TCPRGYELDTDQRTCIDV--DDC----ADSPCCQQVCTNNPGGYECGCYAGYRLSA---- 317
Query: 390 XXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL--DST 447
DG C DVDECA S C C N GS++C C G L D
Sbjct: 318 ---------------DGCGCEDVDECASSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRR 361
Query: 448 GTAPL 452
G +PL
Sbjct: 362 GCSPL 366
Score = 69.7 bits (163), Expect = 2e-11
Identities = 123/484 (25%), Positives = 165/484 (34%), Gaps = 69/484 (14%)
Query: 3 NGGMCTN--GICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGS 60
NGG C + G C+ G C+ G G G CR C + RGRC G+
Sbjct: 484 NGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCAN------RGRCHRLYGA 537
Query: 61 YTCLCEPG----FAPTAAGYCADVDECAADSMC---KGGRCVNSEGSFQCVCEAGYRPTA 113
CLC+PG F A C+ + C C +GS C C+AG+R
Sbjct: 538 --CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS--CSCKAGFRGER 593
Query: 114 TRGAC---VDVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTC-LGLKLGWGV 168
+ C C + C G C + G C GF + G+ C +G +GV
Sbjct: 594 CQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGT---FGV 650
Query: 169 SC-QACPAQGSELYAVL----CPEGPSKDNGGADINE------CTAVPGACPHGSCENLE 217
+C +C G+ + V CP G + ++ AD E C + AC H + + E
Sbjct: 651 NCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPE 710
Query: 218 PGYRCICDPGYHPDADGLCRDI-------DECDMHQSYCAGGQCRNTAGSFTCVCPEGTR 270
G C+C PG+ C+D+ C S G C G C C G
Sbjct: 711 TG-ACLCLPGF---VGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGH--CSCAPGWT 764
Query: 271 HEPELQLCRDIDECEGETETHYIESDYERGD---IPPTFPTRTELASPCDNGRCINTHGG 327
+ C D G +H G I P +C H G
Sbjct: 765 GFSCQRAC-DTGHW-GPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG 822
Query: 328 FECE----CELGYVLDATAQRCLDNRRGSCWR-RVVDGQCEAAAPELLLRQECCCSVGLA 382
CE C+ G D + C + WR + C A L R C C+ G A
Sbjct: 823 PGCEQLCQCQHGAACDHVSGAC---TCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAA 879
Query: 383 WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDE-CALSAELCAGGTCVNTDGSYRCDCPPG 441
+G + RDV C S GG C G RC CP G
Sbjct: 880 --CDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAG 935
Query: 442 LTLD 445
T D
Sbjct: 936 WTGD 939
Score = 43.6 bits (98), Expect = 0.001
Identities = 66/247 (26%), Positives = 89/247 (36%), Gaps = 39/247 (15%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY---- 61
C +G C ++ G C C G+ G C CR C TAG+
Sbjct: 831 CQHGAACDHVSGA--CTCPAGWR----GTFCEHACPAGFFGLDCRSA-CNCTAGAACDAV 883
Query: 62 --TCLCEPGF-APTAAGYCADVDE---CAADSMC-KGGRCVNSEGSFQCVCEAGYRPTAT 114
+CLC G P A C D C C GG C G +C+C AG+
Sbjct: 884 NGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKC 941
Query: 115 RGACVDV---DECEEQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-S 169
+ C+ + C ++ C CH+ G+ C C PGFT S + C + G G
Sbjct: 942 QSPCLRGWFGEACAQRCSCPPAAACHHVTGA--CRCPPGFTGSGCEQGCPPGRYGPGCEQ 999
Query: 170 CQACPAQGS---ELYAVLCPEGPSKDN------GGADINECTAVPGACPHGSCENLEPGY 220
C GS A CP G + G CT V G +C+ +
Sbjct: 1000 LCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG-- 1057
Query: 221 RCICDPG 227
C+C PG
Sbjct: 1058 TCLCPPG 1064
>AF054501-1|AAC39881.1| 161|Homo sapiens latent transforming growth
factor-beta binding protein 4 protein.
Length = 161
Score = 152 bits (368), Expect = 3e-36
Identities = 71/146 (48%), Positives = 85/146 (58%), Gaps = 5/146 (3%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCL 64
+C +GIC N DG FECIC PG+ +G + A C DVDECR+ P +C RC N+ GSY C+
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 60
Query: 65 --CEPGFAPTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C+PG+ G C DVDEC S C C N GSFQC+C+ GY CVDV
Sbjct: 61 RDCDPGYHAGPEGTCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV 120
Query: 122 DECEE-QRVCRNGRCHNTPGSFRCEC 146
+ECE Q VC C N GSF C C
Sbjct: 121 NECETLQGVCGAALCENVEGSFLCVC 146
Score = 91.9 bits (218), Expect = 4e-18
Identities = 53/149 (35%), Positives = 67/149 (44%), Gaps = 13/149 (8%)
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL--------GLKLGWGVSCQACPAQGSEL 180
+C++G C NT GSF C C PG D +CL G L C+ P GS
Sbjct: 1 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP--GSYR 58
Query: 181 YAVLCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CR 237
C G G D++EC H C+NL ++C+CD GY DG C
Sbjct: 59 CVRDCDPGYHAGPEGTCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV 118
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCP 266
D++EC+ Q C C N GSF CVCP
Sbjct: 119 DVNECETLQGVCGAALCENVEGSFLCVCP 147
Score = 85.0 bits (201), Expect = 5e-16
Identities = 43/112 (38%), Positives = 60/112 (53%), Gaps = 8/112 (7%)
Query: 181 YAVLCPEGPSKDNGGA---DINECTAV-PGACPHGSCENLEPGYRCI--CDPGYHPDADG 234
+ +CP G A D++EC P C CEN YRC+ CDPGYH +G
Sbjct: 14 FECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG 73
Query: 235 LCRDIDECDMHQSYC-AGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C D+DEC ++S+C A C+N GSF C+C +G + + C D++ECE
Sbjct: 74 TCDDVDEC-RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE 124
Score = 66.1 bits (154), Expect = 2e-10
Identities = 58/193 (30%), Positives = 73/193 (37%), Gaps = 49/193 (25%)
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPT 308
C G C NT GSF C+CP G R P+L C D+DEC ERG P
Sbjct: 2 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECR------------ERG---PAL-- 44
Query: 309 RTELASPCDNGRCINTHGGFEC--ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAA 366
C + RC N+ G + C +C+ GY A + D+ C R G A
Sbjct: 45 -------CGSQRCENSPGSYRCVRDCDPGY--HAGPEGTCDD-VDECRNRSFCG-AHAVC 93
Query: 367 PELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT 426
L +C C G DG C DV+EC +C
Sbjct: 94 QNLPGSFQCLCDQGYE-------------------GARDGRHCVDVNECETLQGVCGAAL 134
Query: 427 CVNTDGSYRCDCP 439
C N +GS+ C CP
Sbjct: 135 CENVEGSFLCVCP 147
Score = 65.7 bits (153), Expect = 3e-10
Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 3 NGGMC-TNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C + +C+N+ G F+C+C GYE +G C DV+EC VC C N GS+
Sbjct: 83 NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSF 142
Query: 62 TCLC 65
C+C
Sbjct: 143 LCVC 146
Score = 48.8 bits (111), Expect = 4e-05
Identities = 39/126 (30%), Positives = 46/126 (36%), Gaps = 20/126 (15%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C +G C NT G FEC C G+ CLD VD +C P L Q C
Sbjct: 2 CQSGICTNTDGSFECICPPGHRAGPDLASCLD----------VD-ECRERGPALCGSQRC 50
Query: 376 CCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYR 435
S G G+ TC DVDEC + A C N GS++
Sbjct: 51 ENSPG---------SYRCVRDCDPGYHAGPEGTCDDVDECRNRSFCGAHAVCQNLPGSFQ 101
Query: 436 CDCPPG 441
C C G
Sbjct: 102 CLCDQG 107
Score = 44.4 bits (100), Expect = 8e-04
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 405 DGATCRDVDECA-LSAELCAGGTCVNTDGSYRC--DCPPGLTLDSTGT 449
D A+C DVDEC LC C N+ GSYRC DC PG GT
Sbjct: 27 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT 74
Score = 40.7 bits (91), Expect = 0.010
Identities = 14/21 (66%), Positives = 15/21 (71%)
Query: 421 LCAGGTCVNTDGSYRCDCPPG 441
LC G C NTDGS+ C CPPG
Sbjct: 1 LCQSGICTNTDGSFECICPPG 21
>U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor
protein.
Length = 956
Score = 150 bits (363), Expect = 1e-35
Identities = 102/356 (28%), Positives = 148/356 (41%), Gaps = 25/356 (7%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G + C CK GY S+ CR D C C + C N GS+ C C G+A
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
G C VD CA+++ CVN++GS+ C C G+ + C +D C
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG 371
Query: 131 RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW--GVSCQACPAQGSELYAVLCPEG 188
C NT S+ C CL GFTL+ D +TC + C+ E Y C G
Sbjct: 372 CQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRG 431
Query: 189 PSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDM 244
+ D G + ++ C C C N E + C C G+ + D C +D C +
Sbjct: 432 YTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLL 490
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE-GE---------TETHYIE 294
C C N SF C CPEG + + C +D C G+ +E ++
Sbjct: 491 SDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVC 549
Query: 295 SDYERGDIPPTFPT--RTELASPCDNGR---CINTHGGFECECELGYVLDATAQRC 345
+E + T R ++ D+G C+N+ + CEC +G+ L +RC
Sbjct: 550 QCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLVGFRLAEDGKRC 605
Score = 138 bits (333), Expect = 5e-32
Identities = 119/418 (28%), Positives = 155/418 (37%), Gaps = 50/418 (11%)
Query: 54 CRNTAGSYTCLCEPGFAPTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPT 112
C N GSY C C+ G+ + C D CA + CVN GSF C C +GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKL--GWGVSC 170
CV VD C + C N GS+ C+C GF L+ D +TC + C
Sbjct: 313 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGC 372
Query: 171 QACPAQGSELYAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDP 226
Q + Y+ C +G P K IN C C H C N+E Y C C
Sbjct: 373 QHECVNTDDSYSCHCLKGFTLNPDKKTCRR-INYCALNKPGCEH-ECVNMEESYYCRCHR 430
Query: 227 GYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
GY D +G C +D C C C NT SF C C EG +L+ C +D C
Sbjct: 431 GYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCL 489
Query: 286 -GETETHYIESDYERG---DIPPTFPTRTE-----LASPC---DNG---RCINTHGGFEC 330
+ Y + +R P R++ C D+G C+++ F C
Sbjct: 490 LSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVC 549
Query: 331 ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXX 390
+C GY+L + C R+ C + +D CE C C VG
Sbjct: 550 QCFEGYILREDGKTC--RRKDVC--QAIDHGCEHICVNSDDSYTCECLVGFRLAE----- 600
Query: 391 XXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
DG CR D C + C CVN SY C C G L G
Sbjct: 601 --------------DGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDG 643
Score = 134 bits (323), Expect = 8e-31
Identities = 99/341 (29%), Positives = 136/341 (39%), Gaps = 36/341 (10%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C N DG + C C G+ + C +D C + C+ C NT SY+C C GF
Sbjct: 335 CVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTL 393
Query: 72 TA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
C ++ CA + CVN E S+ C C GY C VD C +Q
Sbjct: 394 NPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHG 453
Query: 131 RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSELYAVLCPEG 188
C NT SF C+C GF ++ D +TC + L C+ +A CPEG
Sbjct: 454 CEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEG 513
Query: 189 PSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
+ G A ++ C C H SC + E + C C GY DG CR D C
Sbjct: 514 HVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQA 572
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C C N+ S+TC C G R + + CR D C+ TH+
Sbjct: 573 IDHGCEH-ICVNSDDSYTCECLVGFRLAEDGKRCRRKDVCK---STHH------------ 616
Query: 305 TFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
C++ C+N + C+C G+VL +RC
Sbjct: 617 ----------GCEH-ICVNNGNSYICKCSEGFVLAEDGRRC 646
Score = 63.7 bits (148), Expect = 1e-09
Identities = 66/261 (25%), Positives = 96/261 (36%), Gaps = 42/261 (16%)
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAG 259
C+ + C H C N+ Y C C GY ++D CR D C M C C N G
Sbjct: 242 CSTLEHNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPG 299
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIESD-------YERGDIPPTFPTR 309
SF C C G + + C +D C E E + +D +E + P T
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTC 359
Query: 310 TEL--ASPCDNG---RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEA 364
T++ + ++G C+NT + C C G+ L+ + C R C + CE
Sbjct: 360 TKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTC--RRINYC--ALNKPGCEH 415
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
+ C C G +G TC VD CA C
Sbjct: 416 ECVNMEESYYCRCHRGYTLDP-------------------NGKTCSRVDHCAQQDHGCE- 455
Query: 425 GTCVNTDGSYRCDCPPGLTLD 445
C+NT+ S+ C C G ++
Sbjct: 456 QLCLNTEDSFVCQCSEGFLIN 476
Score = 48.0 bits (109), Expect = 7e-05
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
IC N D + C C G+ +G CR D C+ C C N SY C C GF
Sbjct: 580 ICVNSDDSYTCECLVGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGF 637
>BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein.
Length = 715
Score = 147 bits (357), Expect = 6e-35
Identities = 102/356 (28%), Positives = 146/356 (41%), Gaps = 25/356 (7%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G + C CK GY S+ CR D C C + C N GS+ C C G+A
Sbjct: 12 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 70
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
G C VD CA+++ CVN++GS+ C C G+ C +D C
Sbjct: 71 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHG 130
Query: 131 RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW--GVSCQACPAQGSELYAVLCPEG 188
C NT S+ C CL GFTL+ D +TC + C+ E Y C G
Sbjct: 131 CQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRG 190
Query: 189 PSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDM 244
+ D G + ++ C C C N E + C C G+ + D C +D C +
Sbjct: 191 YTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLL 249
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE-GE---------TETHYIE 294
C C N SF C CPEG + + C +D C G+ +E ++
Sbjct: 250 SDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVC 308
Query: 295 SDYERGDIPPTFPT--RTELASPCDNGR---CINTHGGFECECELGYVLDATAQRC 345
+E + T R ++ D+G C+N+ + CEC G+ L +RC
Sbjct: 309 QCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRC 364
Score = 136 bits (330), Expect = 1e-31
Identities = 100/341 (29%), Positives = 137/341 (40%), Gaps = 36/341 (10%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C N DG + C C G+ + C +D C + C+ C NT SY+C C GF
Sbjct: 94 CVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTL 152
Query: 72 TA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
C ++ CA + CVN E S+ C C GY C VD C +Q
Sbjct: 153 NPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHG 212
Query: 131 RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSELYAVLCPEG 188
C NT SF C+C GF ++ D +TC + L C+ +A CPEG
Sbjct: 213 CEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEG 272
Query: 189 PSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
+ G A ++ C C H SC + E + C C GY DG CR D C
Sbjct: 273 HVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQA 331
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C C N+ S+TC C EG R + + CR D C+ TH+
Sbjct: 332 IDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCK---STHH------------ 375
Query: 305 TFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
C++ C+N + C+C G+VL +RC
Sbjct: 376 ----------GCEH-ICVNNGNSYICKCSEGFVLAEDGRRC 405
Score = 135 bits (327), Expect = 3e-31
Identities = 118/418 (28%), Positives = 154/418 (36%), Gaps = 50/418 (11%)
Query: 54 CRNTAGSYTCLCEPGFAPTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPT 112
C N GSY C C+ G+ + C D CA + CVN GSF C C +GY
Sbjct: 12 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 71
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKL--GWGVSC 170
CV VD C + C N GS+ C+C GF L+ D +TC + C
Sbjct: 72 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHGC 131
Query: 171 QACPAQGSELYAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDP 226
Q + Y+ C +G P K IN C C H C N+E Y C C
Sbjct: 132 QHECVNTDDSYSCHCLKGFTLNPDKKTCRR-INYCALNKPGCEH-ECVNMEESYYCRCHR 189
Query: 227 GYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
GY D +G C +D C C C NT SF C C EG +L+ C +D C
Sbjct: 190 GYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCL 248
Query: 286 -GETETHYIESDYERG---DIPPTFPTRTE-----LASPC---DNG---RCINTHGGFEC 330
+ Y + +R P R++ C D+G C+++ F C
Sbjct: 249 LSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVC 308
Query: 331 ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXX 390
+C GY+L + C R+ C + +D CE C C G
Sbjct: 309 QCFEGYILREDGKTC--RRKDVC--QAIDHGCEHICVNSDDSYTCECLEGFRLAE----- 359
Query: 391 XXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
DG CR D C + C CVN SY C C G L G
Sbjct: 360 --------------DGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDG 402
Score = 63.7 bits (148), Expect = 1e-09
Identities = 66/261 (25%), Positives = 96/261 (36%), Gaps = 42/261 (16%)
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAG 259
C+ + C H C N+ Y C C GY ++D CR D C M C C N G
Sbjct: 1 CSTLEHNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPG 58
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIESD-------YERGDIPPTFPTR 309
SF C C G + + C +D C E E + +D +E + P T
Sbjct: 59 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTC 118
Query: 310 TEL--ASPCDNG---RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEA 364
T++ + ++G C+NT + C C G+ L+ + C R C + CE
Sbjct: 119 TKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTC--RRINYC--ALNKPGCEH 174
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
+ C C G +G TC VD CA C
Sbjct: 175 ECVNMEESYYCRCHRGYTLDP-------------------NGKTCSRVDHCAQQDHGCE- 214
Query: 425 GTCVNTDGSYRCDCPPGLTLD 445
C+NT+ S+ C C G ++
Sbjct: 215 QLCLNTEDSFVCQCSEGFLIN 235
Score = 48.4 bits (110), Expect = 5e-05
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
IC N D + C C G+ +G CR D C+ C C N SY C C GF
Sbjct: 339 ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGF 396
>BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein.
Length = 937
Score = 147 bits (357), Expect = 6e-35
Identities = 102/356 (28%), Positives = 146/356 (41%), Gaps = 25/356 (7%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G + C CK GY S+ CR D C C + C N GS+ C C G+A
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
G C VD CA+++ CVN++GS+ C C G+ C +D C
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHG 371
Query: 131 RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW--GVSCQACPAQGSELYAVLCPEG 188
C NT S+ C CL GFTL+ D +TC + C+ E Y C G
Sbjct: 372 CQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRG 431
Query: 189 PSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDM 244
+ D G + ++ C C C N E + C C G+ + D C +D C +
Sbjct: 432 YTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLL 490
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE-GE---------TETHYIE 294
C C N SF C CPEG + + C +D C G+ +E ++
Sbjct: 491 SDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVC 549
Query: 295 SDYERGDIPPTFPT--RTELASPCDNGR---CINTHGGFECECELGYVLDATAQRC 345
+E + T R ++ D+G C+N+ + CEC G+ L +RC
Sbjct: 550 QCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRC 605
Score = 136 bits (330), Expect = 1e-31
Identities = 100/341 (29%), Positives = 137/341 (40%), Gaps = 36/341 (10%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C N DG + C C G+ + C +D C + C+ C NT SY+C C GF
Sbjct: 335 CVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTL 393
Query: 72 TA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
C ++ CA + CVN E S+ C C GY C VD C +Q
Sbjct: 394 NPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHG 453
Query: 131 RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSELYAVLCPEG 188
C NT SF C+C GF ++ D +TC + L C+ +A CPEG
Sbjct: 454 CEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEG 513
Query: 189 PSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
+ G A ++ C C H SC + E + C C GY DG CR D C
Sbjct: 514 HVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQA 572
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C C N+ S+TC C EG R + + CR D C+ TH+
Sbjct: 573 IDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCK---STHH------------ 616
Query: 305 TFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
C++ C+N + C+C G+VL +RC
Sbjct: 617 ----------GCEH-ICVNNGNSYICKCSEGFVLAEDGRRC 646
Score = 135 bits (327), Expect = 3e-31
Identities = 118/418 (28%), Positives = 154/418 (36%), Gaps = 50/418 (11%)
Query: 54 CRNTAGSYTCLCEPGFAPTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPT 112
C N GSY C C+ G+ + C D CA + CVN GSF C C +GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKL--GWGVSC 170
CV VD C + C N GS+ C+C GF L+ D +TC + C
Sbjct: 313 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHGC 372
Query: 171 QACPAQGSELYAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDP 226
Q + Y+ C +G P K IN C C H C N+E Y C C
Sbjct: 373 QHECVNTDDSYSCHCLKGFTLNPDKKTCRR-INYCALNKPGCEH-ECVNMEESYYCRCHR 430
Query: 227 GYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
GY D +G C +D C C C NT SF C C EG +L+ C +D C
Sbjct: 431 GYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCL 489
Query: 286 -GETETHYIESDYERG---DIPPTFPTRTE-----LASPC---DNG---RCINTHGGFEC 330
+ Y + +R P R++ C D+G C+++ F C
Sbjct: 490 LSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVC 549
Query: 331 ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXX 390
+C GY+L + C R+ C + +D CE C C G
Sbjct: 550 QCFEGYILREDGKTC--RRKDVC--QAIDHGCEHICVNSDDSYTCECLEGFRLAE----- 600
Query: 391 XXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
DG CR D C + C CVN SY C C G L G
Sbjct: 601 --------------DGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDG 643
Score = 63.7 bits (148), Expect = 1e-09
Identities = 66/261 (25%), Positives = 96/261 (36%), Gaps = 42/261 (16%)
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAG 259
C+ + C H C N+ Y C C GY ++D CR D C M C C N G
Sbjct: 242 CSTLEHNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPG 299
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIESD-------YERGDIPPTFPTR 309
SF C C G + + C +D C E E + +D +E + P T
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTC 359
Query: 310 TEL--ASPCDNG---RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEA 364
T++ + ++G C+NT + C C G+ L+ + C R C + CE
Sbjct: 360 TKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTC--RRINYC--ALNKPGCEH 415
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
+ C C G +G TC VD CA C
Sbjct: 416 ECVNMEESYYCRCHRGYTLDP-------------------NGKTCSRVDHCAQQDHGCE- 455
Query: 425 GTCVNTDGSYRCDCPPGLTLD 445
C+NT+ S+ C C G ++
Sbjct: 456 QLCLNTEDSFVCQCSEGFLIN 476
Score = 48.4 bits (110), Expect = 5e-05
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
IC N D + C C G+ +G CR D C+ C C N SY C C GF
Sbjct: 580 ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGF 637
>AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein
protein.
Length = 1016
Score = 147 bits (357), Expect = 6e-35
Identities = 102/356 (28%), Positives = 146/356 (41%), Gaps = 25/356 (7%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G + C CK GY S+ CR D C C + C N GS+ C C G+A
Sbjct: 313 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 371
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
G C VD CA+++ CVN++GS+ C C G+ C +D C
Sbjct: 372 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHG 431
Query: 131 RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW--GVSCQACPAQGSELYAVLCPEG 188
C NT S+ C CL GFTL+ D +TC + C+ E Y C G
Sbjct: 432 CQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRG 491
Query: 189 PSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDECDM 244
+ D G + ++ C C C N E + C C G+ + D C +D C +
Sbjct: 492 YTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLL 550
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE-GE---------TETHYIE 294
C C N SF C CPEG + + C +D C G+ +E ++
Sbjct: 551 SDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVC 609
Query: 295 SDYERGDIPPTFPT--RTELASPCDNGR---CINTHGGFECECELGYVLDATAQRC 345
+E + T R ++ D+G C+N+ + CEC G+ L +RC
Sbjct: 610 QCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRC 665
Score = 136 bits (330), Expect = 1e-31
Identities = 100/341 (29%), Positives = 137/341 (40%), Gaps = 36/341 (10%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C N DG + C C G+ + C +D C + C+ C NT SY+C C GF
Sbjct: 395 CVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTL 453
Query: 72 TA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
C ++ CA + CVN E S+ C C GY C VD C +Q
Sbjct: 454 NPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHG 513
Query: 131 RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSELYAVLCPEG 188
C NT SF C+C GF ++ D +TC + L C+ +A CPEG
Sbjct: 514 CEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEG 573
Query: 189 PSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDM 244
+ G A ++ C C H SC + E + C C GY DG CR D C
Sbjct: 574 HVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQA 632
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C C N+ S+TC C EG R + + CR D C+ TH+
Sbjct: 633 IDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCK---STHH------------ 676
Query: 305 TFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
C++ C+N + C+C G+VL +RC
Sbjct: 677 ----------GCEH-ICVNNGNSYICKCSEGFVLAEDGRRC 706
Score = 135 bits (327), Expect = 3e-31
Identities = 118/418 (28%), Positives = 154/418 (36%), Gaps = 50/418 (11%)
Query: 54 CRNTAGSYTCLCEPGFAPTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPT 112
C N GSY C C+ G+ + C D CA + CVN GSF C C +GY
Sbjct: 313 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 372
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKL--GWGVSC 170
CV VD C + C N GS+ C+C GF L+ D +TC + C
Sbjct: 373 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSNHGC 432
Query: 171 QACPAQGSELYAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDP 226
Q + Y+ C +G P K IN C C H C N+E Y C C
Sbjct: 433 QHECVNTDDSYSCHCLKGFTLNPDKKTCRR-INYCALNKPGCEH-ECVNMEESYYCRCHR 490
Query: 227 GYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
GY D +G C +D C C C NT SF C C EG +L+ C +D C
Sbjct: 491 GYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCL 549
Query: 286 -GETETHYIESDYERG---DIPPTFPTRTE-----LASPC---DNG---RCINTHGGFEC 330
+ Y + +R P R++ C D+G C+++ F C
Sbjct: 550 LSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVC 609
Query: 331 ECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXX 390
+C GY+L + C R+ C + +D CE C C G
Sbjct: 610 QCFEGYILREDGKTC--RRKDVC--QAIDHGCEHICVNSDDSYTCECLEGFRLAE----- 660
Query: 391 XXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
DG CR D C + C CVN SY C C G L G
Sbjct: 661 --------------DGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDG 703
Score = 63.7 bits (148), Expect = 1e-09
Identities = 66/261 (25%), Positives = 96/261 (36%), Gaps = 42/261 (16%)
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAG 259
C+ + C H C N+ Y C C GY ++D CR D C M C C N G
Sbjct: 302 CSTLEHNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPG 359
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIESD-------YERGDIPPTFPTR 309
SF C C G + + C +D C E E + +D +E + P T
Sbjct: 360 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTC 419
Query: 310 TEL--ASPCDNG---RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEA 364
T++ + ++G C+NT + C C G+ L+ + C R C + CE
Sbjct: 420 TKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTC--RRINYC--ALNKPGCEH 475
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
+ C C G +G TC VD CA C
Sbjct: 476 ECVNMEESYYCRCHRGYTLDP-------------------NGKTCSRVDHCAQQDHGCE- 515
Query: 425 GTCVNTDGSYRCDCPPGLTLD 445
C+NT+ S+ C C G ++
Sbjct: 516 QLCLNTEDSFVCQCSEGFLIN 536
Score = 48.4 bits (110), Expect = 5e-05
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
IC N D + C C G+ +G CR D C+ C C N SY C C GF
Sbjct: 640 ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGF 697
>X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein.
Length = 886
Score = 147 bits (355), Expect = 1e-34
Identities = 96/293 (32%), Positives = 132/293 (45%), Gaps = 64/293 (21%)
Query: 12 CKNIDGGFECICKPGYESGS-------EGALCRDVDECRDNPRVC-RRGRCRNTAGSYTC 63
C N + C CK G+ S + G C+D+DEC +P+ C C+N +G Y C
Sbjct: 47 CTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
Query: 64 LCEPGF-APTAAGY---------CADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPT 112
C GF +PT + C D++EC +C + CVNS GS+ C C+ G+
Sbjct: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSRVCPEHSDCVNSMGSYSCSCQVGF--I 164
Query: 113 ATRGACVDVDECEEQRVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ 171
+ C DV+EC + R C + C+NT G++ C C PGF S+ +C GLK SC+
Sbjct: 165 SRNSTCEDVNECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSCQGLK----ASCE 220
Query: 172 ACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACP-HGSCENLEPGYRCICDPGYHP 230
DI+ECT + CP + +C N Y C C PG+ P
Sbjct: 221 -------------------------DIDECTEM---CPINSTCTNTPGSYFCTCHPGFAP 252
Query: 231 DADGL--------CRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPE 274
+ L CRDIDEC S C C N GS++C C G PE
Sbjct: 253 SSGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIVGFHPNPE 305
Score = 106 bits (254), Expect = 2e-22
Identities = 79/249 (31%), Positives = 112/249 (44%), Gaps = 51/249 (20%)
Query: 9 NGICKNIDGGFECICKPGYES--------GSEGAL-CRDVDECRDNPRVC-RRGRCRNTA 58
N CKN+ G ++C C G+ S G G C D++EC + RVC C N+
Sbjct: 94 NSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS-RVCPEHSDCVNSM 152
Query: 59 GSYTCLCEPGFAPTAAGYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTA---- 113
GSY+C C+ GF + C DV+ECA C + C N+ G++ C C G+ ++
Sbjct: 153 GSYSCSCQVGFI-SRNSTCEDVNECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLS 211
Query: 114 ---TRGACVDVDECEEQRVCR-NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS 169
+ +C D+DEC E +C N C NTPGS+ C C PGF S+ G+ GV
Sbjct: 212 CQGLKASCEDIDECTE--MCPINSTCTNTPGSYFCTCHPGFAPSS-GQLNF---TDQGVE 265
Query: 170 CQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
C+ C + PS C P+ C N Y C C G+H
Sbjct: 266 CRDIDE---------CRQDPS---------TCG------PNSICTNALGSYSCGCIVGFH 301
Query: 230 PDADGLCRD 238
P+ +G +D
Sbjct: 302 PNPEGSQKD 310
Score = 98.7 bits (235), Expect = 4e-20
Identities = 78/251 (31%), Positives = 108/251 (43%), Gaps = 46/251 (18%)
Query: 81 DECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRG-------ACVDVDECEEQ-RVCR 131
+ C ++C C N+ S+ C C+ G+ + + C D+DEC + + C
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
Query: 132 -NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---------QACPAQGSEL- 180
N C N G ++C CL GF+ S G + K G SC + CP +
Sbjct: 93 PNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKPG-NFSCTDINECLTSRVCPEHSDCVN 150
Query: 181 ----YAVLCPEG-PSKDNGGADINECTAVPGACP-HGSCENLEPGYRCICDPGY-----H 229
Y+ C G S+++ D+NEC A P ACP H +C N Y C C+PG+ H
Sbjct: 151 SMGSYSCSCQVGFISRNSTCEDVNEC-ADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 209
Query: 230 PDADGL---CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQL------CR 279
GL C DIDEC + C NT GS+ C C G +L CR
Sbjct: 210 LSCQGLKASCEDIDECT--EMCPINSTCTNTPGSYFCTCHPGFAPSSGQLNFTDQGVECR 267
Query: 280 DIDECEGETET 290
DIDEC + T
Sbjct: 268 DIDECRQDPST 278
Score = 66.5 bits (155), Expect = 2e-10
Identities = 68/265 (25%), Positives = 96/265 (36%), Gaps = 49/265 (18%)
Query: 197 DINECTAVPGAC-PHGSCENLEPGYRCICDPGYH--------PDADG--LCRDIDECDMH 245
DI+EC+ P C P+ SC+NL Y+C C G+ P G C DI+EC
Sbjct: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS 139
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
+ C N+ GS++C C G C D++EC P
Sbjct: 140 RVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVNECAD----------------PRA 181
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
P ++ C NT G + C C G+ + C + SC +D +C
Sbjct: 182 CP---------EHATCNNTVGNYSCFCNPGFESSSGHLSC-QGLKASC--EDID-ECTEM 228
Query: 366 APELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-G 424
P + C + G + + F G CRD+DEC C
Sbjct: 229 CP---INSTCTNTPGSYFCTCHPGFAPSSGQL--NFTD-QGVECRDIDECRQDPSTCGPN 282
Query: 425 GTCVNTDGSYRCDCPPGLTLDSTGT 449
C N GSY C C G + G+
Sbjct: 283 SICTNALGSYSCGCIVGFHPNPEGS 307
Score = 65.7 bits (153), Expect = 3e-10
Identities = 63/250 (25%), Positives = 93/250 (37%), Gaps = 47/250 (18%)
Query: 208 CP-HGSCENLEPGYRCICDPGY-------HPDADGL-CRDIDECDMHQSYCA-GGQCRNT 257
CP + +C N Y C C G+ H G+ C+DIDEC C C+N
Sbjct: 41 CPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNL 100
Query: 258 AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCD 317
+G + C C +G G ++ DI +R P +
Sbjct: 101 SGRYKCSCLDG------------FSSPTGNDWVPGKPGNFSCTDINECLTSRV---CP-E 144
Query: 318 NGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCC 377
+ C+N+ G + C C++G++ + C D + R + A + C C
Sbjct: 145 HSDCVNSMGSYSCSCQVGFI--SRNSTCEDVNECADPRACPE---HATCNNTVGNYSCFC 199
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRC 436
+ G S +G A+C D+DEC E+C TC NT GSY C
Sbjct: 200 NPGFESSSGHLSC--------QGLK----ASCEDIDECT---EMCPINSTCTNTPGSYFC 244
Query: 437 DCPPGLTLDS 446
C PG S
Sbjct: 245 TCHPGFAPSS 254
>AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein.
Length = 915
Score = 144 bits (349), Expect = 6e-34
Identities = 104/342 (30%), Positives = 137/342 (40%), Gaps = 36/342 (10%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+C N+ G F C C GY +G C VD C C C N GSY C C GFA
Sbjct: 293 LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFA 351
Query: 71 PTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
C ++ CA + CVN E S+ C C GY C VD C +Q
Sbjct: 352 LNPDEKTCTRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDH 411
Query: 130 CRNGRCHNTPGSFRCECLPGFTLSNDGRTC--LGLKLGWGVSCQACPAQGSELYAVLCPE 187
C NT SF C+C GF ++ D +TC + L C+ +A CPE
Sbjct: 412 GCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPE 471
Query: 188 GPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECD 243
G + G A ++ C C H SC + E + C C GY DG CR D C
Sbjct: 472 GHVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQ 530
Query: 244 MHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIP 303
C C N+ S+TC C EG R + + CR D C+ TH+
Sbjct: 531 AIDHGCE-HICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCK---STHH----------- 575
Query: 304 PTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
C++ C+N + C+C G+VL +RC
Sbjct: 576 -----------GCEH-ICVNNGNSYICKCSEGFVLAEDGRRC 605
Score = 119 bits (287), Expect = 2e-26
Identities = 106/379 (27%), Positives = 142/379 (37%), Gaps = 53/379 (13%)
Query: 94 CVNSEGSFQCVCEAGYRPTATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTL 152
C+N GS+ C C+ GY + + C D C E C C N PGSF C+C G+ L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 153 SNDGRTCLGLKL----GWGVSCQACPAQGSELYAVLCPEGPS---KDNGGADINECTAVP 205
+ DG+ C+ + G + A GS Y C EG + + IN C
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGS--YLCQCHEGFALNPDEKTCTRINYCALNK 369
Query: 206 GACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCV 264
C H C N+E Y C C GY D +G C +D C C C NT SF C
Sbjct: 370 PGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQ 427
Query: 265 CPEGTRHEPELQLCRDIDECE-GETETHYIESDYERG---DIPPTFPTRTE-----LASP 315
C EG +L+ C +D C + Y + +R P R++
Sbjct: 428 CSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDS 487
Query: 316 C---DNG---RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPEL 369
C D+G C+++ F C+C GY+L + C R+ C + +D CE
Sbjct: 488 CALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTC--RRKDVC--QAIDHGCEHICVNS 543
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C G DG CR D C + C CVN
Sbjct: 544 DDSYTCECLEGFRLAE-------------------DGKRCRRKDVCKSTHHGCEH-ICVN 583
Query: 430 TDGSYRCDCPPGLTLDSTG 448
SY C C G L G
Sbjct: 584 NGNSYICKCSEGFVLAEDG 602
Score = 113 bits (273), Expect = 9e-25
Identities = 87/314 (27%), Positives = 125/314 (39%), Gaps = 24/314 (7%)
Query: 54 CRNTAGSYTCLCEPGFAPTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPT 112
C N GSY C C+ G+ + C D CA + CVN GSF C C +GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW--GVSC 170
CV VD C + C N GS+ C+C GF L+ D +TC + C
Sbjct: 313 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTRINYCALNKPGC 372
Query: 171 QACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPG 227
+ E Y C G + D G + ++ C C C N E + C C G
Sbjct: 373 EHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEG 431
Query: 228 YHPDAD-GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE- 285
+ + D C +D C + C C N SF C CPEG + + C +D C
Sbjct: 432 FLINEDLKTCSRVDYCLLSDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCAL 490
Query: 286 GE---------TETHYIESDYERGDIPPTFPT--RTELASPCDNGR---CINTHGGFECE 331
G+ +E ++ +E + T R ++ D+G C+N+ + CE
Sbjct: 491 GDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCE 550
Query: 332 CELGYVLDATAQRC 345
C G+ L +RC
Sbjct: 551 CLEGFRLAEDGKRC 564
Score = 76.6 bits (180), Expect = 2e-13
Identities = 76/264 (28%), Positives = 96/264 (36%), Gaps = 42/264 (15%)
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAG 259
C+ + C H C N+ Y C C GY ++D CR D C M C C N G
Sbjct: 242 CSTLEHNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPG 299
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIESD-------YERGDIPPTFPTR 309
SF C C G + + C +D C E E + +D +E + P T
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTC 359
Query: 310 TE-----LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEA 364
T L P C+N + C C GY LD + C +R C ++ D CE
Sbjct: 360 TRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTC--SRVDHCAQQ--DHGCEQ 415
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
C CS G D TC VD C LS C
Sbjct: 416 LCLNTEDSFVCQCSEGF-------------------LINEDLKTCSRVDYCLLSDHGCE- 455
Query: 425 GTCVNTDGSYRCDCPPGLTLDSTG 448
+CVN D S+ C CP G L S G
Sbjct: 456 YSCVNMDRSFACQCPEGHVLRSDG 479
>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
Length = 1235
Score = 142 bits (345), Expect = 2e-33
Identities = 88/285 (30%), Positives = 136/285 (47%), Gaps = 33/285 (11%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + G+EC C G+ G LC + +D C +P C G+C++ SYTC+
Sbjct: 541 CLNGAKCIDHPNGYECQCATGFT----GVLCEENIDNCDPDP--CHHGQCQDGIDSYTCI 594
Query: 65 CEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PG+ C+D +DEC + GRC++ +QC C+ G T+ ++ D+
Sbjct: 595 CNPGY---MGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPG---TSGVNCEINFDD 648
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSEL 180
C C +G C + + C C PGFT + D C G +C G
Sbjct: 649 C-ASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC----INGVNG 703
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
+ +CPEGP + + +NEC + P C HG+C GY+C+CD G+ G+ ++D
Sbjct: 704 FRCICPEGPHHPSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW----VGINCEVD 757
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
+ + + C GG C N + C C +G + Q+ +IDEC
Sbjct: 758 KNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGY-NCQV--NIDEC 799
Score = 140 bits (338), Expect = 1e-32
Identities = 111/385 (28%), Positives = 164/385 (42%), Gaps = 52/385 (13%)
Query: 1 MTNGGMCTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNT 57
M N C + G C N DG F C C GY G C D++EC +P C+ C +
Sbjct: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDP--CQNDATCLDK 474
Query: 58 AGSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG 116
G +TCLC PGF +C +++EC ++ G+CV+ FQC+C G+ T
Sbjct: 475 IGGFTCLCMPGFKGV---HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGP 527
Query: 117 AC-VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQA 172
C +D+D+C +C + P + C+C GFT + C G CQ
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQ- 585
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
G + Y +C G I+EC + P G C +L GY+C C PG
Sbjct: 586 ---DGIDSYTCICNPGYMGAICSDQIDECYSSP-CLNDGRCIDLVNGYQCNCQPG----T 637
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDEC------E 285
G+ +I+ D + C G C + ++CVC G Q C DIDEC +
Sbjct: 638 SGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG----QRCNIDIDECASNPCRK 693
Query: 286 GETETHYIESDY----ERGDIPPTFPTRTE-LASPCDNGRCINTHGGFECECELGYV--- 337
G T + + E P + E L++PC +G C G++C C+ G+V
Sbjct: 694 GATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGIN 753
Query: 338 LDATAQRCLDN--RRGSCWRRVVDG 360
+ CL N + G +V+G
Sbjct: 754 CEVDKNECLSNPCQNGGTCDNLVNG 778
Score = 137 bits (332), Expect = 7e-32
Identities = 131/472 (27%), Positives = 182/472 (38%), Gaps = 58/472 (12%)
Query: 7 CTNG-ICKNIDGG-FECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC 63
C NG C + +EC C+ G+ +G E C+ D C +P C G C A ++C
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGF-TGKE---CQWTDACLSHP--CANGSTCTTVANQFSC 168
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C GF T DV+EC C+ GG C+N GS+QC C G+ V
Sbjct: 169 KCLTGF--TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVP-- 224
Query: 123 ECEEQRVCRNGRCHNTPG-SFRCECLPGFTLSNDGRT---CLGLKLGWGVSCQACPAQGS 178
C G C T +F C CLPGF S R C + G C G
Sbjct: 225 -CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVC----VDGV 279
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCR 237
Y CP + D++EC P AC +G +C N GY C+C G+ D
Sbjct: 280 NTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW--SGDDCSE 337
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR----HEPELQL---CRDIDECE-GETE 289
+ID+C S G C + SF+C+CPEG H + + C C+
Sbjct: 338 NIDDCAF-ASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLN 396
Query: 290 THYI---ESDYERGDIPPTFPTRTELAS-PCDN-GRCINTHGGFECECELGYV---LDAT 341
YI Y+ D S PC++ G+C+NT G F CEC GY +
Sbjct: 397 GQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMD 456
Query: 342 AQRCLDN---RRGSCWRRVVDGQC------EAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
C + +C ++ C + EL + EC + + G
Sbjct: 457 INECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEIN-ECQSNPCVNNGQCVDKVNR 515
Query: 393 XXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
GF G C+ D+D+C+ S G C++ Y C C G T
Sbjct: 516 FQCLCPPGFT---GPVCQIDIDDCS-STPCLNGAKCIDHPNGYECQCATGFT 563
Score = 136 bits (330), Expect = 1e-31
Identities = 128/456 (28%), Positives = 182/456 (39%), Gaps = 64/456 (14%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C N+ G+ C CK G++ G C+ ++DEC NP + +G C + YTC
Sbjct: 766 CQNGGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECASNPCL-NQGTCFDDISGYTCH 820
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGR-CVNSEG--SFQCVCEAGYRPTATRGACVDV 121
C P C V + + C+ C S S+ C+C G++ + +D+
Sbjct: 821 C---VLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQG---QRCTIDI 874
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGS 178
DEC + +G CHNT GS+ CEC PGF+ D CL G SC G
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCM----DGV 930
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCR 237
++ LC G + D D+NEC + P C + G+C + Y C C G+ D
Sbjct: 931 NTFSCLCLPGFTGDKYQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF--DGVHCEN 986
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR--------HEPELQLCRDIDECEGETE 289
+I+EC S GG C + SF+C+CP G +E C + C
Sbjct: 987 NINEC-TESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLG 1045
Query: 290 THYIESDYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGYVLDATAQRCL 346
T+ G T L SPC N G C+ +C C G+
Sbjct: 1046 TY--RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW---------- 1093
Query: 347 DNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
+ V + C+ AA + E C G G+ G
Sbjct: 1094 ----AGAYCDVPNVSCDIAASRRGVLVEHLCQHS---GVCINAGNTHYCQCPLGYT---G 1143
Query: 407 ATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ C + +DECA S G TC + G YRC+C PG
Sbjct: 1144 SYCEEQLDECA-SNPCQHGATCSDFIGGYRCECVPG 1178
Score = 132 bits (319), Expect = 2e-30
Identities = 128/454 (28%), Positives = 182/454 (40%), Gaps = 57/454 (12%)
Query: 15 IDGGFECICKPGYESGSEGALC-RDVDECR-DNPRVCRR-GRCRNTAGSYTCLCEPGFAP 71
++G + C C GY+ GA C DVDEC N C G+C NT G++ C C G+A
Sbjct: 395 LNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
Query: 72 TAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCR 131
D++EC +D C++ G F C+C G++ ++++EC+
Sbjct: 451 PRCEM--DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCE---LEINECQSNPCVN 505
Query: 132 NGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG 188
NG+C + F+C C PGFT D C G C P G Y C G
Sbjct: 506 NGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP-NG---YECQCATG 561
Query: 189 PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD-IDECDMHQS 247
+ +I+ C P C HG C++ Y CIC+PGY +C D IDEC + S
Sbjct: 562 FTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGY---MGAICSDQIDEC--YSS 614
Query: 248 YCAG-GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD----YERGDI 302
C G+C + + C C GT + + D+C H I D Y
Sbjct: 615 PCLNDGRCIDLVNGYQCNCQPGT---SGVNCEINFDDCASNPCIHGICMDGINRYSCVCS 671
Query: 303 PPTFPTRTEL------ASPCDNG-RCINTHGGFECECELG---YVLDATAQRCLDNR--R 350
P R + ++PC G CIN GF C C G + CL N
Sbjct: 672 PGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIH 731
Query: 351 GSCWRRVVDGQCEAAAPELLL-----RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLD 405
G+C + +C A + + + EC + G+ KGF
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGF---K 788
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDC 438
G C+ ++DECA S GTC + Y C C
Sbjct: 789 GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC 821
Score = 125 bits (302), Expect = 3e-28
Identities = 133/477 (27%), Positives = 189/477 (39%), Gaps = 76/477 (15%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N G C ++ G++C C+PG + G C + D+C NP C G C + Y+C+
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNP--CIHGICMDGINRYSCV 669
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG-YRPTATRGACVDVDE 123
C PGF T D+DECA++ KG C+N F+C+C G + P+ V+E
Sbjct: 670 CSPGF--TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYS----QVNE 723
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGSEL 180
C C +G C ++C C G+ N D CL G +C G
Sbjct: 724 C-LSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL-VNG--- 778
Query: 181 YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDID 240
Y C +G N +I+EC + P G+C + GY C C Y
Sbjct: 779 YRCTCKKGFKGYNCQVNIDECASNP-CLNQGTCFDDISGYTCHCVLPYTG---------K 828
Query: 241 ECDMHQSYCAGGQCRNTA--------GSFTCVCPEGTRHEPELQLCRDIDECEGET---- 288
C + C+ C N A S+TC+C G + + + DIDEC +
Sbjct: 829 NCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ---RCTIDIDECISKPCMNH 885
Query: 289 -ETHYIESDYERGDIPPTF-------PTRTELASPCDN-GRCINTHGGFECECELGYVLD 339
H + Y + PP F LA+PC N G C++ F C C G+ D
Sbjct: 886 GLCHNTQGSY-MCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGD 944
Query: 340 ---ATAQRCLD---NRRGSCWRRVVDGQCEAAAPELLLR-----QECCCSVGLAWGSXXX 388
CL G+C V C+ A + EC S G+
Sbjct: 945 KYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVD 1004
Query: 389 XXXXXXXXXXKGFAKLDGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPGLT 443
GF G+ C +++EC S+ C GTCV+ G+YRC CP G T
Sbjct: 1005 GINSFSCLCPVGFT---GSFCLHEINEC--SSHPCLNEGTCVDGLGTYRCSCPLGYT 1056
Score = 122 bits (295), Expect = 2e-27
Identities = 93/346 (26%), Positives = 138/346 (39%), Gaps = 35/346 (10%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C NG+ GF CIC G S V+EC NP C G C Y C
Sbjct: 694 GATCINGV-----NGFRCICPEGPHHPS---CYSQVNECLSNP--CIHGNCTGGLSGYKC 743
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
LC+ G+ D +EC ++ GG C N ++C C+ G++ + V++DE
Sbjct: 744 LCDAGWVGINCE--VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ---VNIDE 798
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYA 182
C G C + + C C+ +T N + C + E Y
Sbjct: 799 CASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP-DADGLCRDIDE 241
LC G DI+EC + P HG C N + Y C C PG+ D + DID+
Sbjct: 859 CLCAPGWQGQRCTIDIDECISKP-CMNHGLCHNTQGSYMCECPPGFSGMDCE---EDIDD 914
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEGETETHYIES--- 295
C + GG C + +F+C+C P G +++ ++ C G T + Y+ S
Sbjct: 915 C-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKYQTDMNECLSEPCKNGGTCSDYVNSYTC 973
Query: 296 ----DYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGY 336
++ TE S C NG C++ F C C +G+
Sbjct: 974 KCQAGFDGVHCENNINECTE--SSCFNGGTCVDGINSFSCLCPVGF 1017
Score = 116 bits (279), Expect = 2e-25
Identities = 121/470 (25%), Positives = 174/470 (37%), Gaps = 60/470 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGS 60
NGG+C +G+ + C C P + G C DVDEC P C+ G C N G
Sbjct: 271 NGGVCVDGV-----NTYNCRCPPQWT----GQFCTEDVDECLLQPNACQNGGTCANRNGG 321
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
Y C+C G++ ++D+CA S G C++ SF C+C P G
Sbjct: 322 YGCVCVNGWSGDDCS--ENIDDCAFASCTPGSTCIDRVASFSCMC-----PEGKAGLLCH 374
Query: 121 VDECEEQRVCRNGR-CHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACP 174
+D+ C G C P G + C C G+ + D C C
Sbjct: 375 LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCV 434
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDAD 233
+ C +G + DINEC + P C + +C + G+ C+C PG+
Sbjct: 435 NTDGAFHCE-CLKGYAGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFKGVHC 491
Query: 234 GLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYI 293
L +I+EC + GQC + F C+CP G P Q+ DID+C +
Sbjct: 492 EL--EINECQSNPC-VNNGQCVDKVNRFQCLCPPGFT-GPVCQI--DIDDCSSTPCLNGA 545
Query: 294 ES-DYERGDIPPTFPTRTEL----------ASPCDNGRCINTHGGFECECELGY---VLD 339
+ D+ G T + PC +G+C + + C C GY +
Sbjct: 546 KCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICS 605
Query: 340 ATAQRCLDN---RRGSCWRRVVDGQCE----AAAPELLLRQECCCSVGLAWGSXXXXXXX 392
C + G C V QC + + + C S G
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINR 665
Query: 393 XXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G C D+DECA S G TC+N +RC CP G
Sbjct: 666 YSCVCSPGFT---GQRCNIDIDECA-SNPCRKGATCINGVNGFRCICPEG 711
Score = 116 bits (278), Expect = 2e-25
Identities = 100/352 (28%), Positives = 146/352 (41%), Gaps = 40/352 (11%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCL 64
C N G+C N G + C C PG+ SG + D+D+C NP C+ G C + +++CL
Sbjct: 882 CMNHGLCHNTQGSYMCECPPGF-SGMDCE--EDIDDCLANP--CQNGGSCMDGVNTFSCL 936
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C PGF T Y D++EC ++ GG C + S+ C C+AG+ +++EC
Sbjct: 937 CLPGF--TGDKYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCEN---NINEC 991
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLG-LKLGWGVSC--QACPAQGSELY 181
E G C + SF C C GFT G CL + C + G Y
Sbjct: 992 TESSCFNGGTCVDGINSFSCLCPVGFT----GSFCLHEINECSSHPCLNEGTCVDGLGTY 1047
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGY---HPDADGLCR 237
CP G + N +N C+ P C + G+C + +C+C G+ + D +
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSP--CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC 1105
Query: 238 DIDECD---MHQSYCA-GGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETET 290
DI + + C G C N + C CP G+ E +L C G T +
Sbjct: 1106 DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCS 1165
Query: 291 HYIESDYERGDIPPTFPTRTELA------SPCDNG-RCINTHGGFECECELG 335
+I Y +P E PC NG CI+ F+C C G
Sbjct: 1166 DFI-GGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG 1216
Score = 106 bits (255), Expect = 1e-22
Identities = 125/435 (28%), Positives = 162/435 (37%), Gaps = 48/435 (11%)
Query: 41 ECRDNPRVC-RRGRCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSE 98
+CRD C G C G+ C C GF YC D C + GG CV
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFL---GEYCQHRDPCEKNRCQNGGTCVAQA 83
Query: 99 --GSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNG-RCHN-TPGSFRCECLPGFTLSN 154
G C C +G+ T C R C NG CH + ++ C C GFT
Sbjct: 84 MLGKATCRCASGF--TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE 141
Query: 155 DGRT--CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG- 211
T CL G +C Q ++ C G + D+NEC +PG C HG
Sbjct: 142 CQWTDACLSHPCANGSTCTTVANQ----FSCKCLTGFTGQKCETDVNECD-IPGHCQHGG 196
Query: 212 SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAG-SFTCVC-P-- 266
+C NL Y+C C G+ G D S C GG CR T +F C C P
Sbjct: 197 TCLNLPGSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGF 252
Query: 267 EGTRHEPELQ-----LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP--CDNG 319
EG+ E + C++ C T+ + T L P C NG
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNG 312
Query: 320 -RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWR------RVVDGQC---EAAAPEL 369
C N +GG+ C C G+ D ++ D SC RV C E A L
Sbjct: 313 GTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLL 372
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALS-AELCA-GGT 426
+ C S G+ GA C DVDECA++ + C G
Sbjct: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGK 432
Query: 427 CVNTDGSYRCDCPPG 441
CVNTDG++ C+C G
Sbjct: 433 CVNTDGAFHCECLKG 447
Score = 103 bits (246), Expect = 2e-21
Identities = 82/298 (27%), Positives = 122/298 (40%), Gaps = 38/298 (12%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSY 61
NGG C +G+ F C+C PG+ D++EC P C+ G C + SY
Sbjct: 922 NGGSCMDGV-----NTFSCLCLPGFTGDKYQT---DMNECLSEP--CKNGGTCSDYVNSY 971
Query: 62 TCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV- 119
TC C+ GF +C + ++EC S GG CV+ SF C+C G+ T C+
Sbjct: 972 TCKCQAGFDGV---HCENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCLH 1024
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
+++EC G C + G++RC C G+T N +T + L + Q
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKN-CQTLVNLCSRSPCKNKGTCVQKKA 1083
Query: 180 LYAVLCPEG--------PSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHP 230
LCP G P+ A V C H G C N + C C GY
Sbjct: 1084 ESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY-- 1141
Query: 231 DADGLCRD-IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE 287
C + +DEC + G C + G + C C G + + ++DEC+ +
Sbjct: 1142 -TGSYCEEQLDECASNPCQ-HGATCSDFIGGYRCECVPGYQ---GVNCEYEVDECQNQ 1194
Score = 100 bits (240), Expect = 9e-21
Identities = 81/281 (28%), Positives = 123/281 (43%), Gaps = 37/281 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C + + C C+ G++ G C + ++EC ++ G C + S++CL
Sbjct: 958 CKNGGTCSDYVNSYTCKCQAGFD----GVHCENNINECTESS-CFNGGTCVDGINSFSCL 1012
Query: 65 CEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C GF +C +++EC++ G CV+ G+++C C GY T C +
Sbjct: 1013 CPVGFT---GSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY----TGKNCQTLVN 1065
Query: 124 CEEQRVCRN-GRCHNTPGSFRCECLPGFT-----LSNDGRTCLGLKLGWGVS--CQ---A 172
+ C+N G C +C C G+ + N + G V CQ
Sbjct: 1066 LCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGV 1125
Query: 173 CPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPD 231
C G+ Y CP G + ++EC + P C HG+ C + GYRC C PGY
Sbjct: 1126 CINAGNTHYCQ-CPLGYTGSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQ-- 1180
Query: 232 ADGL-CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTR 270
G+ C ++DEC +Q GG C + F C CP GTR
Sbjct: 1181 --GVNCEYEVDECQ-NQPCQNGGTCIDLVNHFKCSCPPGTR 1218
Score = 91.1 bits (216), Expect = 7e-18
Identities = 78/291 (26%), Positives = 112/291 (38%), Gaps = 32/291 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA-GSY 61
NGG C + + + G C C G+ E C + G C + +Y
Sbjct: 75 NGGTC---VAQAMLGKATCRCASGFTG--EDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY 129
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VD 120
C C+ GF C D C + G C F C C G+ T C D
Sbjct: 130 ECTCQVGFTGKE---CQWTDACLSHPCANGSTCTTVANQFSCKCLTGF----TGQKCETD 182
Query: 121 VDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWG----VSCQACPA 175
V+EC+ C++G C N PGS++C+C GFT G+ C L + V+ C
Sbjct: 183 VNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSLYVPCAPSPCVNGGTCRQ 238
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADG 234
G + C G +I++C C +G C + Y C C P +
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNIDDCP--NHRCQNGGVCVDGVNTYNCRCPPQW--TGQF 294
Query: 235 LCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
D+DEC + + C GG C N G + CVC G + +ID+C
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD---DCSENIDDC 342
Score = 60.5 bits (140), Expect = 1e-08
Identities = 97/386 (25%), Positives = 135/386 (34%), Gaps = 53/386 (13%)
Query: 70 APTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
AP A C D + C + MC G+ C C G+ C D CE+ R
Sbjct: 21 APAHALQCRDGYEPCVNEGMC----VTYHNGTGYCKCPEGFLGEY----CQHRDPCEKNR 72
Query: 129 VCRNGRC--HNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ---ACPAQGSELYAV 183
G C G C C GFT D + C C + Y
Sbjct: 73 CQNGGTCVAQAMLGKATCRCASGFT-GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYEC 131
Query: 184 LCPEG-PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR-DID 240
C G K+ D C + P C +GS C + + C C G+ C D++
Sbjct: 132 TCQVGFTGKECQWTDA--CLSHP--CANGSTCTTVANQFSCKCLTGFTGQK---CETDVN 184
Query: 241 ECDMHQSYCAGGQCRNTAGSFTCVCPEG--TRHEPELQL-CRDIDECEGETETHYIESDY 297
ECD+ GG C N GS+ C CP+G ++ L + C G T + +
Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTF 244
Query: 298 ERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRR 356
E +P + E C N RC N GG C G ++ RC G
Sbjct: 245 ECNCLPGFEGSTCERNIDDCPNHRCQN--GGV---CVDG--VNTYNCRCPPQWTGQF--- 294
Query: 357 VVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDEC 415
C E LL+ C + G+ G++ G C ++D+C
Sbjct: 295 -----CTEDVDECLLQPNACQN----GGTCANRNGGYGCVCVNGWS---GDDCSENIDDC 342
Query: 416 ALSAELCAGGTCVNTDGSYRCDCPPG 441
A A G TC++ S+ C CP G
Sbjct: 343 AF-ASCTPGSTCIDRVASFSCMCPEG 367
Score = 46.8 bits (106), Expect = 2e-04
Identities = 86/353 (24%), Positives = 116/353 (32%), Gaps = 59/353 (16%)
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSNDGRTCLGL 162
C GY P G CV HN G+ C+C GF C
Sbjct: 28 CRDGYEPCVNEGMCVTY--------------HN--GTGYCKCPEGFLGEYCQHRDPCEKN 71
Query: 163 KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPG-Y 220
+ G +C A G C G + ++ + V C +G +C L Y
Sbjct: 72 RCQNGGTCVAQAMLGKA--TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY 129
Query: 221 RCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEG---TRHEPELQ 276
C C G+ C+ D C H CA G C A F+C C G + E ++
Sbjct: 130 ECTCQVGFTGKE---CQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
Query: 277 LCRDIDECEGETETHYIESDYERGDIPPTFPTR--TELASPCDNGRCINTHGGFECECEL 334
C C+ + Y+ P F + L PC C+N G C
Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQC-QCPQGFTGQYCDSLYVPCAPSPCVN---GGTCRQTG 240
Query: 335 GYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXX 394
+ + CL GS R +D C P + C G+
Sbjct: 241 DFTFECN---CLPGFEGSTCERNID-DC----PNHRCQNGGVCVDGV------------N 280
Query: 395 XXXXKGFAKLDGATC-RDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLD 445
+ + G C DVDEC L C GGTC N +G Y C C G + D
Sbjct: 281 TYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD 333
Score = 35.9 bits (79), Expect = 0.29
Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 2/37 (5%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C +VDEC + GGTC++ ++C CPPG
Sbjct: 1181 GVNCEYEVDECQ-NQPCQNGGTCIDLVNHFKCSCPPG 1216
>CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein.
Length = 443
Score = 139 bits (337), Expect = 2e-32
Identities = 98/278 (35%), Positives = 126/278 (45%), Gaps = 42/278 (15%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCLCEPGFA----------- 70
C GYE + CRDV+EC P C+ +C N G Y CL
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 71 ---------PTAAGY-------CADVDECA-ADSMCKGGR-CVNSEGSFQCVCEAGYRPT 112
P GY C DVDECA A C+ + C N GS+QC C GYR
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI 158
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQ 171
CVD+DEC R C++ RC N PGSFRC+C PGF L + R+C+ + + G C+
Sbjct: 159 GPE--CVDIDEC-RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCE 214
Query: 172 ACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPG-YRCICDPG 227
+ C +G G +DI+EC+ C + C N EPG + C C G
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVN-EPGRFSCHCPQG 272
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV 264
Y A LC+DIDEC+ C+ Q C N G + CV
Sbjct: 273 YQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 113 bits (272), Expect = 1e-24
Identities = 59/143 (41%), Positives = 72/143 (50%), Gaps = 9/143 (6%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF-- 69
C N+ G ++C C GY G C D+DECR R C+ RC N GS+ C CEPGF
Sbjct: 140 CHNLPGSYQCTCPDGYRK--IGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQL 194
Query: 70 APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
P C DV+EC + C+ RC NS G+F C C GY +C D+DEC
Sbjct: 195 GPNNRS-CVDVNECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 130 CRNGRCHNTPGSFRCECLPGFTL 152
RC N PG F C C G+ L
Sbjct: 253 LCQYRCVNEPGRFSCHCPQGYQL 275
Score = 109 bits (263), Expect = 1e-23
Identities = 55/136 (40%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C N+ G F C C+PG++ G C DV+EC D C + RC N+ G++ C C G+
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRV 129
G+ C+D+DEC+ S RCVN G F C C GY+ ATR C D+DECE
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATR-LCQDIDECESGAHQ 293
Query: 130 CRNGR-CHNTPGSFRC 144
C + C N G +RC
Sbjct: 294 CSEAQTCVNFHGGYRC 309
Score = 89.4 bits (212), Expect = 2e-17
Identities = 96/339 (28%), Positives = 125/339 (36%), Gaps = 75/339 (22%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNG-RCHNTPGSFRCECLP-GFTLSNDGRTCLG 161
C GY C DV+EC C+ +C N G + C LP + ND
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC--LPRSAAVINDLH---- 92
Query: 162 LKLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGGADINECTAVPGAC-PHGSCENLEP 218
G G PAQ + CP G P + D++EC C P C NL
Sbjct: 93 ---GEGPPPPVPPAQ----HPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPG 145
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
Y+C C GY C DIDEC YC +C N GSF C C G + P + C
Sbjct: 146 SYQCTCPDGYRKIGPE-CVDIDEC--RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
D++EC+ + +PC+ RC N++G F C C GY L
Sbjct: 202 VDVNECD--------------------------MGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 339 DATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX 398
C D +D E + L + C G
Sbjct: 235 HRDGFSCSD----------ID---ECSYSSYLCQYRCVNEPG-----------RFSCHCP 270
Query: 399 KGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRC 436
+G+ L C+D+DEC A C+ TCVN G YRC
Sbjct: 271 QGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 69.7 bits (163), Expect = 2e-11
Identities = 86/316 (27%), Positives = 122/316 (38%), Gaps = 51/316 (16%)
Query: 60 SYTCLCEPGFA-PTAAGYCADVDECAA-DSMCKGG-RCVNSEGSFQCVCEAGYRPTATRG 116
SYT C G+ + +C DV+EC CKG +C+N G + C+ R
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL---------PRS 84
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
A V D E P C PG+ +D +C+ + P+Q
Sbjct: 85 AAVINDLHGE-----GPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQ 138
Query: 177 GSE----LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
Y CP+G K DI+EC C H C NL +RC C+PG+
Sbjct: 139 DCHNLPGSYQCTCPDGYRKIGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLG 195
Query: 232 ADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
+ C D++ECDM C +C N+ G+F C C +G + C DIDEC +
Sbjct: 196 PNNRSCVDVNECDMGAP-CEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYL 253
Query: 291 HYIESDYERGDIPPTFPTRTELAS--------PCDNG--------RCINTHGGFEC---- 330
E G P +L + C++G C+N HGG+ C
Sbjct: 254 CQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTN 313
Query: 331 ECELGYVLDATAQRCL 346
C Y+ + RCL
Sbjct: 314 RCVEPYI-QVSENRCL 328
Score = 61.7 bits (143), Expect = 5e-09
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 58/267 (21%)
Query: 197 DINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
D+NEC +P AC C N GY C+ P + + D+ + G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLCL------PRSAAVINDL--------HGEGPPPP 99
Query: 256 NTAGSFTCVCPEGTRHEPELQ-LCRDIDEC-------EGETETHYIESDYE------RGD 301
CP G +EP+ Q C D+DEC + H + Y+
Sbjct: 100 VPPAQHPNPCPPG--YEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQ 361
I P E RC+N G F C+CE G+ L + C+D +
Sbjct: 158 IGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVN-----------E 206
Query: 362 CEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAE 420
C+ AP Q C S G +G+ DG +C D+DEC+ S+
Sbjct: 207 CDMGAP---CEQRCFNSYG-----------TFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 421 LCAGGTCVNTDGSYRCDCPPGLTLDST 447
LC CVN G + C CP G L +T
Sbjct: 253 LCQ-YRCVNEPGRFSCHCPQGYQLLAT 278
>BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 2 protein.
Length = 443
Score = 139 bits (337), Expect = 2e-32
Identities = 98/278 (35%), Positives = 126/278 (45%), Gaps = 42/278 (15%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCLCEPGFA----------- 70
C GYE + CRDV+EC P C+ +C N G Y CL
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 71 ---------PTAAGY-------CADVDECA-ADSMCKGGR-CVNSEGSFQCVCEAGYRPT 112
P GY C DVDECA A C+ + C N GS+QC C GYR
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI 158
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQ 171
CVD+DEC R C++ RC N PGSFRC+C PGF L + R+C+ + + G C+
Sbjct: 159 GPE--CVDIDEC-RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCE 214
Query: 172 ACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPG-YRCICDPG 227
+ C +G G +DI+EC+ C + C N EPG + C C G
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVN-EPGRFSCHCPQG 272
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV 264
Y A LC+DIDEC+ C+ Q C N G + CV
Sbjct: 273 YQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 113 bits (272), Expect = 1e-24
Identities = 59/143 (41%), Positives = 72/143 (50%), Gaps = 9/143 (6%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF-- 69
C N+ G ++C C GY G C D+DECR R C+ RC N GS+ C CEPGF
Sbjct: 140 CHNLPGSYQCTCPDGYRK--IGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQL 194
Query: 70 APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
P C DV+EC + C+ RC NS G+F C C GY +C D+DEC
Sbjct: 195 GPNNRS-CVDVNECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 130 CRNGRCHNTPGSFRCECLPGFTL 152
RC N PG F C C G+ L
Sbjct: 253 LCQYRCVNEPGRFSCHCPQGYQL 275
Score = 109 bits (263), Expect = 1e-23
Identities = 55/136 (40%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C N+ G F C C+PG++ G C DV+EC D C + RC N+ G++ C C G+
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRV 129
G+ C+D+DEC+ S RCVN G F C C GY+ ATR C D+DECE
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATR-LCQDIDECESGAHQ 293
Query: 130 CRNGR-CHNTPGSFRC 144
C + C N G +RC
Sbjct: 294 CSEAQTCVNFHGGYRC 309
Score = 89.4 bits (212), Expect = 2e-17
Identities = 96/339 (28%), Positives = 125/339 (36%), Gaps = 75/339 (22%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNG-RCHNTPGSFRCECLP-GFTLSNDGRTCLG 161
C GY C DV+EC C+ +C N G + C LP + ND
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC--LPRSAAVINDLH---- 92
Query: 162 LKLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGGADINECTAVPGAC-PHGSCENLEP 218
G G PAQ + CP G P + D++EC C P C NL
Sbjct: 93 ---GEGPPPPVPPAQ----HPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPG 145
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
Y+C C GY C DIDEC YC +C N GSF C C G + P + C
Sbjct: 146 SYQCTCPDGYRKIGPE-CVDIDEC--RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
D++EC+ + +PC+ RC N++G F C C GY L
Sbjct: 202 VDVNECD--------------------------MGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 339 DATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX 398
C D +D E + L + C G
Sbjct: 235 HRDGFSCSD----------ID---ECSYSSYLCQYRCVNEPG-----------RFSCHCP 270
Query: 399 KGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRC 436
+G+ L C+D+DEC A C+ TCVN G YRC
Sbjct: 271 QGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 69.7 bits (163), Expect = 2e-11
Identities = 86/316 (27%), Positives = 122/316 (38%), Gaps = 51/316 (16%)
Query: 60 SYTCLCEPGFA-PTAAGYCADVDECAA-DSMCKGG-RCVNSEGSFQCVCEAGYRPTATRG 116
SYT C G+ + +C DV+EC CKG +C+N G + C+ R
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL---------PRS 84
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
A V D E P C PG+ +D +C+ + P+Q
Sbjct: 85 AAVINDLHGE-----GPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQ 138
Query: 177 GSE----LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
Y CP+G K DI+EC C H C NL +RC C+PG+
Sbjct: 139 DCHNLPGSYQCTCPDGYRKIGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLG 195
Query: 232 ADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
+ C D++ECDM C +C N+ G+F C C +G + C DIDEC +
Sbjct: 196 PNNRSCVDVNECDMGAP-CEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYL 253
Query: 291 HYIESDYERGDIPPTFPTRTELAS--------PCDNG--------RCINTHGGFEC---- 330
E G P +L + C++G C+N HGG+ C
Sbjct: 254 CQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTN 313
Query: 331 ECELGYVLDATAQRCL 346
C Y+ + RCL
Sbjct: 314 RCVEPYI-QVSENRCL 328
Score = 61.7 bits (143), Expect = 5e-09
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 58/267 (21%)
Query: 197 DINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
D+NEC +P AC C N GY C+ P + + D+ + G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLCL------PRSAAVINDL--------HGEGPPPP 99
Query: 256 NTAGSFTCVCPEGTRHEPELQ-LCRDIDEC-------EGETETHYIESDYE------RGD 301
CP G +EP+ Q C D+DEC + H + Y+
Sbjct: 100 VPPAQHPNPCPPG--YEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQ 361
I P E RC+N G F C+CE G+ L + C+D +
Sbjct: 158 IGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVN-----------E 206
Query: 362 CEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAE 420
C+ AP Q C S G +G+ DG +C D+DEC+ S+
Sbjct: 207 CDMGAP---CEQRCFNSYG-----------TFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 421 LCAGGTCVNTDGSYRCDCPPGLTLDST 447
LC CVN G + C CP G L +T
Sbjct: 253 LCQ-YRCVNEPGRFSCHCPQGYQLLAT 278
>AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein.
Length = 443
Score = 139 bits (337), Expect = 2e-32
Identities = 98/278 (35%), Positives = 126/278 (45%), Gaps = 42/278 (15%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCLCEPGFA----------- 70
C GYE + CRDV+EC P C+ +C N G Y CL
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 71 ---------PTAAGY-------CADVDECA-ADSMCKGGR-CVNSEGSFQCVCEAGYRPT 112
P GY C DVDECA A C+ + C N GS+QC C GYR
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI 158
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQ 171
CVD+DEC R C++ RC N PGSFRC+C PGF L + R+C+ + + G C+
Sbjct: 159 GPE--CVDIDEC-RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCE 214
Query: 172 ACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPG-YRCICDPG 227
+ C +G G +DI+EC+ C + C N EPG + C C G
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVN-EPGRFSCHCPQG 272
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV 264
Y A LC+DIDEC+ C+ Q C N G + CV
Sbjct: 273 YQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 113 bits (272), Expect = 1e-24
Identities = 59/143 (41%), Positives = 72/143 (50%), Gaps = 9/143 (6%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF-- 69
C N+ G ++C C GY G C D+DECR R C+ RC N GS+ C CEPGF
Sbjct: 140 CHNLPGSYQCTCPDGYRK--IGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQL 194
Query: 70 APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
P C DV+EC + C+ RC NS G+F C C GY +C D+DEC
Sbjct: 195 GPNNRS-CVDVNECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 130 CRNGRCHNTPGSFRCECLPGFTL 152
RC N PG F C C G+ L
Sbjct: 253 LCQYRCVNEPGRFSCHCPQGYQL 275
Score = 109 bits (263), Expect = 1e-23
Identities = 55/136 (40%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C N+ G F C C+PG++ G C DV+EC D C + RC N+ G++ C C G+
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRV 129
G+ C+D+DEC+ S RCVN G F C C GY+ ATR C D+DECE
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATR-LCQDIDECESGAHQ 293
Query: 130 CRNGR-CHNTPGSFRC 144
C + C N G +RC
Sbjct: 294 CSEAQTCVNFHGGYRC 309
Score = 89.4 bits (212), Expect = 2e-17
Identities = 96/339 (28%), Positives = 125/339 (36%), Gaps = 75/339 (22%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNG-RCHNTPGSFRCECLP-GFTLSNDGRTCLG 161
C GY C DV+EC C+ +C N G + C LP + ND
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC--LPRSAAVINDLH---- 92
Query: 162 LKLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGGADINECTAVPGAC-PHGSCENLEP 218
G G PAQ + CP G P + D++EC C P C NL
Sbjct: 93 ---GEGPPPPVPPAQ----HPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPG 145
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
Y+C C GY C DIDEC YC +C N GSF C C G + P + C
Sbjct: 146 SYQCTCPDGYRKIGPE-CVDIDEC--RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
D++EC+ + +PC+ RC N++G F C C GY L
Sbjct: 202 VDVNECD--------------------------MGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 339 DATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX 398
C D +D E + L + C G
Sbjct: 235 HRDGFSCSD----------ID---ECSYSSYLCQYRCVNEPG-----------RFSCHCP 270
Query: 399 KGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRC 436
+G+ L C+D+DEC A C+ TCVN G YRC
Sbjct: 271 QGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 69.7 bits (163), Expect = 2e-11
Identities = 86/316 (27%), Positives = 122/316 (38%), Gaps = 51/316 (16%)
Query: 60 SYTCLCEPGFA-PTAAGYCADVDECAA-DSMCKGG-RCVNSEGSFQCVCEAGYRPTATRG 116
SYT C G+ + +C DV+EC CKG +C+N G + C+ R
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL---------PRS 84
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
A V D E P C PG+ +D +C+ + P+Q
Sbjct: 85 AAVINDLHGE-----GPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQ 138
Query: 177 GSE----LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
Y CP+G K DI+EC C H C NL +RC C+PG+
Sbjct: 139 DCHNLPGSYQCTCPDGYRKIGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLG 195
Query: 232 ADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
+ C D++ECDM C +C N+ G+F C C +G + C DIDEC +
Sbjct: 196 PNNRSCVDVNECDMGAP-CEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYL 253
Query: 291 HYIESDYERGDIPPTFPTRTELAS--------PCDNG--------RCINTHGGFEC---- 330
E G P +L + C++G C+N HGG+ C
Sbjct: 254 CQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTN 313
Query: 331 ECELGYVLDATAQRCL 346
C Y+ + RCL
Sbjct: 314 RCVEPYI-QVSENRCL 328
Score = 61.7 bits (143), Expect = 5e-09
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 58/267 (21%)
Query: 197 DINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
D+NEC +P AC C N GY C+ P + + D+ + G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLCL------PRSAAVINDL--------HGEGPPPP 99
Query: 256 NTAGSFTCVCPEGTRHEPELQ-LCRDIDEC-------EGETETHYIESDYE------RGD 301
CP G +EP+ Q C D+DEC + H + Y+
Sbjct: 100 VPPAQHPNPCPPG--YEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQ 361
I P E RC+N G F C+CE G+ L + C+D +
Sbjct: 158 IGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVN-----------E 206
Query: 362 CEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAE 420
C+ AP Q C S G +G+ DG +C D+DEC+ S+
Sbjct: 207 CDMGAP---CEQRCFNSYG-----------TFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 421 LCAGGTCVNTDGSYRCDCPPGLTLDST 447
LC CVN G + C CP G L +T
Sbjct: 253 LCQ-YRCVNEPGRFSCHCPQGYQLLAT 278
>AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein.
Length = 443
Score = 139 bits (337), Expect = 2e-32
Identities = 98/278 (35%), Positives = 126/278 (45%), Gaps = 42/278 (15%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCLCEPGFA----------- 70
C GYE + CRDV+EC P C+ +C N G Y CL
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 71 ---------PTAAGY-------CADVDECA-ADSMCKGGR-CVNSEGSFQCVCEAGYRPT 112
P GY C DVDECA A C+ + C N GS+QC C GYR
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI 158
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQ 171
CVD+DEC R C++ RC N PGSFRC+C PGF L + R+C+ + + G C+
Sbjct: 159 GPE--CVDIDEC-RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCE 214
Query: 172 ACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPG-YRCICDPG 227
+ C +G G +DI+EC+ C + C N EPG + C C G
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVN-EPGRFSCHCPQG 272
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV 264
Y A LC+DIDEC+ C+ Q C N G + CV
Sbjct: 273 YQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 113 bits (272), Expect = 1e-24
Identities = 59/143 (41%), Positives = 72/143 (50%), Gaps = 9/143 (6%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF-- 69
C N+ G ++C C GY G C D+DECR R C+ RC N GS+ C CEPGF
Sbjct: 140 CHNLPGSYQCTCPDGYRK--IGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQL 194
Query: 70 APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
P C DV+EC + C+ RC NS G+F C C GY +C D+DEC
Sbjct: 195 GPNNRS-CVDVNECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 130 CRNGRCHNTPGSFRCECLPGFTL 152
RC N PG F C C G+ L
Sbjct: 253 LCQYRCVNEPGRFSCHCPQGYQL 275
Score = 109 bits (263), Expect = 1e-23
Identities = 55/136 (40%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C N+ G F C C+PG++ G C DV+EC D C + RC N+ G++ C C G+
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRV 129
G+ C+D+DEC+ S RCVN G F C C GY+ ATR C D+DECE
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATR-LCQDIDECESGAHQ 293
Query: 130 CRNGR-CHNTPGSFRC 144
C + C N G +RC
Sbjct: 294 CSEAQTCVNFHGGYRC 309
Score = 89.4 bits (212), Expect = 2e-17
Identities = 96/339 (28%), Positives = 125/339 (36%), Gaps = 75/339 (22%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNG-RCHNTPGSFRCECLP-GFTLSNDGRTCLG 161
C GY C DV+EC C+ +C N G + C LP + ND
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC--LPRSAAVINDLH---- 92
Query: 162 LKLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGGADINECTAVPGAC-PHGSCENLEP 218
G G PAQ + CP G P + D++EC C P C NL
Sbjct: 93 ---GEGPPPPVPPAQ----HPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPG 145
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
Y+C C GY C DIDEC YC +C N GSF C C G + P + C
Sbjct: 146 SYQCTCPDGYRKIGPE-CVDIDEC--RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
D++EC+ + +PC+ RC N++G F C C GY L
Sbjct: 202 VDVNECD--------------------------MGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 339 DATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX 398
C D +D E + L + C G
Sbjct: 235 HRDGFSCSD----------ID---ECSYSSYLCQYRCVNEPG-----------RFSCHCP 270
Query: 399 KGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRC 436
+G+ L C+D+DEC A C+ TCVN G YRC
Sbjct: 271 QGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 69.7 bits (163), Expect = 2e-11
Identities = 86/316 (27%), Positives = 122/316 (38%), Gaps = 51/316 (16%)
Query: 60 SYTCLCEPGFA-PTAAGYCADVDECAA-DSMCKGG-RCVNSEGSFQCVCEAGYRPTATRG 116
SYT C G+ + +C DV+EC CKG +C+N G + C+ R
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL---------PRS 84
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
A V D E P C PG+ +D +C+ + P+Q
Sbjct: 85 AAVINDLHGE-----GPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQ 138
Query: 177 GSE----LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
Y CP+G K DI+EC C H C NL +RC C+PG+
Sbjct: 139 DCHNLPGSYQCTCPDGYRKIGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLG 195
Query: 232 ADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
+ C D++ECDM C +C N+ G+F C C +G + C DIDEC +
Sbjct: 196 PNNRSCVDVNECDMGAP-CEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYL 253
Query: 291 HYIESDYERGDIPPTFPTRTELAS--------PCDNG--------RCINTHGGFEC---- 330
E G P +L + C++G C+N HGG+ C
Sbjct: 254 CQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTN 313
Query: 331 ECELGYVLDATAQRCL 346
C Y+ + RCL
Sbjct: 314 RCVEPYI-QVSENRCL 328
Score = 61.7 bits (143), Expect = 5e-09
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 58/267 (21%)
Query: 197 DINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
D+NEC +P AC C N GY C+ P + + D+ + G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLCL------PRSAAVINDL--------HGEGPPPP 99
Query: 256 NTAGSFTCVCPEGTRHEPELQ-LCRDIDEC-------EGETETHYIESDYE------RGD 301
CP G +EP+ Q C D+DEC + H + Y+
Sbjct: 100 VPPAQHPNPCPPG--YEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQ 361
I P E RC+N G F C+CE G+ L + C+D +
Sbjct: 158 IGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVN-----------E 206
Query: 362 CEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAE 420
C+ AP Q C S G +G+ DG +C D+DEC+ S+
Sbjct: 207 CDMGAP---CEQRCFNSYG-----------TFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 421 LCAGGTCVNTDGSYRCDCPPGLTLDST 447
LC CVN G + C CP G L +T
Sbjct: 253 LCQ-YRCVNEPGRFSCHCPQGYQLLAT 278
>AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 2 protein.
Length = 443
Score = 139 bits (337), Expect = 2e-32
Identities = 98/278 (35%), Positives = 126/278 (45%), Gaps = 42/278 (15%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCLCEPGFA----------- 70
C GYE + CRDV+EC P C+ +C N G Y CL
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 71 ---------PTAAGY-------CADVDECA-ADSMCKGGR-CVNSEGSFQCVCEAGYRPT 112
P GY C DVDECA A C+ + C N GS+QC C GYR
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI 158
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQ 171
CVD+DEC R C++ RC N PGSFRC+C PGF L + R+C+ + + G C+
Sbjct: 159 GPE--CVDIDEC-RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCE 214
Query: 172 ACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPG-YRCICDPG 227
+ C +G G +DI+EC+ C + C N EPG + C C G
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVN-EPGRFSCHCPQG 272
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV 264
Y A LC+DIDEC+ C+ Q C N G + CV
Sbjct: 273 YQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 113 bits (272), Expect = 1e-24
Identities = 59/143 (41%), Positives = 72/143 (50%), Gaps = 9/143 (6%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF-- 69
C N+ G ++C C GY G C D+DECR R C+ RC N GS+ C CEPGF
Sbjct: 140 CHNLPGSYQCTCPDGYRK--IGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQL 194
Query: 70 APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
P C DV+EC + C+ RC NS G+F C C GY +C D+DEC
Sbjct: 195 GPNNRS-CVDVNECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 130 CRNGRCHNTPGSFRCECLPGFTL 152
RC N PG F C C G+ L
Sbjct: 253 LCQYRCVNEPGRFSCHCPQGYQL 275
Score = 109 bits (263), Expect = 1e-23
Identities = 55/136 (40%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C N+ G F C C+PG++ G C DV+EC D C + RC N+ G++ C C G+
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRV 129
G+ C+D+DEC+ S RCVN G F C C GY+ ATR C D+DECE
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATR-LCQDIDECESGAHQ 293
Query: 130 CRNGR-CHNTPGSFRC 144
C + C N G +RC
Sbjct: 294 CSEAQTCVNFHGGYRC 309
Score = 89.4 bits (212), Expect = 2e-17
Identities = 96/339 (28%), Positives = 125/339 (36%), Gaps = 75/339 (22%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNG-RCHNTPGSFRCECLP-GFTLSNDGRTCLG 161
C GY C DV+EC C+ +C N G + C LP + ND
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC--LPRSAAVINDLH---- 92
Query: 162 LKLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGGADINECTAVPGAC-PHGSCENLEP 218
G G PAQ + CP G P + D++EC C P C NL
Sbjct: 93 ---GEGPPPPVPPAQ----HPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPG 145
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
Y+C C GY C DIDEC YC +C N GSF C C G + P + C
Sbjct: 146 SYQCTCPDGYRKIGPE-CVDIDEC--RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
D++EC+ + +PC+ RC N++G F C C GY L
Sbjct: 202 VDVNECD--------------------------MGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 339 DATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX 398
C D +D E + L + C G
Sbjct: 235 HRDGFSCSD----------ID---ECSYSSYLCQYRCVNEPG-----------RFSCHCP 270
Query: 399 KGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRC 436
+G+ L C+D+DEC A C+ TCVN G YRC
Sbjct: 271 QGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 69.7 bits (163), Expect = 2e-11
Identities = 86/316 (27%), Positives = 122/316 (38%), Gaps = 51/316 (16%)
Query: 60 SYTCLCEPGFA-PTAAGYCADVDECAA-DSMCKGG-RCVNSEGSFQCVCEAGYRPTATRG 116
SYT C G+ + +C DV+EC CKG +C+N G + C+ R
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL---------PRS 84
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
A V D E P C PG+ +D +C+ + P+Q
Sbjct: 85 AAVINDLHGE-----GPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQ 138
Query: 177 GSE----LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
Y CP+G K DI+EC C H C NL +RC C+PG+
Sbjct: 139 DCHNLPGSYQCTCPDGYRKIGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLG 195
Query: 232 ADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
+ C D++ECDM C +C N+ G+F C C +G + C DIDEC +
Sbjct: 196 PNNRSCVDVNECDMGAP-CEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYL 253
Query: 291 HYIESDYERGDIPPTFPTRTELAS--------PCDNG--------RCINTHGGFEC---- 330
E G P +L + C++G C+N HGG+ C
Sbjct: 254 CQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTN 313
Query: 331 ECELGYVLDATAQRCL 346
C Y+ + RCL
Sbjct: 314 RCVEPYI-QVSENRCL 328
Score = 61.7 bits (143), Expect = 5e-09
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 58/267 (21%)
Query: 197 DINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
D+NEC +P AC C N GY C+ P + + D+ + G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLCL------PRSAAVINDL--------HGEGPPPP 99
Query: 256 NTAGSFTCVCPEGTRHEPELQ-LCRDIDEC-------EGETETHYIESDYE------RGD 301
CP G +EP+ Q C D+DEC + H + Y+
Sbjct: 100 VPPAQHPNPCPPG--YEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQ 361
I P E RC+N G F C+CE G+ L + C+D +
Sbjct: 158 IGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVN-----------E 206
Query: 362 CEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAE 420
C+ AP Q C S G +G+ DG +C D+DEC+ S+
Sbjct: 207 CDMGAP---CEQRCFNSYG-----------TFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 421 LCAGGTCVNTDGSYRCDCPPGLTLDST 447
LC CVN G + C CP G L +T
Sbjct: 253 LCQ-YRCVNEPGRFSCHCPQGYQLLAT 278
>AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding protein
1 (MBP1) protein.
Length = 443
Score = 139 bits (337), Expect = 2e-32
Identities = 98/278 (35%), Positives = 126/278 (45%), Gaps = 42/278 (15%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCLCEPGFA----------- 70
C GYE + CRDV+EC P C+ +C N G Y CL
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 71 ---------PTAAGY-------CADVDECA-ADSMCKGGR-CVNSEGSFQCVCEAGYRPT 112
P GY C DVDECA A C+ + C N GS+QC C GYR
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKI 158
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQ 171
CVD+DEC R C++ RC N PGSFRC+C PGF L + R+C+ + + G C+
Sbjct: 159 GPE--CVDIDEC-RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCE 214
Query: 172 ACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPG-YRCICDPG 227
+ C +G G +DI+EC+ C + C N EPG + C C G
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVN-EPGRFSCHCPQG 272
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV 264
Y A LC+DIDEC+ C+ Q C N G + CV
Sbjct: 273 YQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 113 bits (272), Expect = 1e-24
Identities = 59/143 (41%), Positives = 72/143 (50%), Gaps = 9/143 (6%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF-- 69
C N+ G ++C C GY G C D+DECR R C+ RC N GS+ C CEPGF
Sbjct: 140 CHNLPGSYQCTCPDGYRK--IGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQL 194
Query: 70 APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
P C DV+EC + C+ RC NS G+F C C GY +C D+DEC
Sbjct: 195 GPNNRS-CVDVNECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 130 CRNGRCHNTPGSFRCECLPGFTL 152
RC N PG F C C G+ L
Sbjct: 253 LCQYRCVNEPGRFSCHCPQGYQL 275
Score = 109 bits (263), Expect = 1e-23
Identities = 55/136 (40%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C N+ G F C C+PG++ G C DV+EC D C + RC N+ G++ C C G+
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRV 129
G+ C+D+DEC+ S RCVN G F C C GY+ ATR C D+DECE
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATR-LCQDIDECESGAHQ 293
Query: 130 CRNGR-CHNTPGSFRC 144
C + C N G +RC
Sbjct: 294 CSEAQTCVNFHGGYRC 309
Score = 89.4 bits (212), Expect = 2e-17
Identities = 96/339 (28%), Positives = 125/339 (36%), Gaps = 75/339 (22%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNG-RCHNTPGSFRCECLP-GFTLSNDGRTCLG 161
C GY C DV+EC C+ +C N G + C LP + ND
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC--LPRSAAVINDLH---- 92
Query: 162 LKLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGGADINECTAVPGAC-PHGSCENLEP 218
G G PAQ + CP G P + D++EC C P C NL
Sbjct: 93 ---GEGPPPPVPPAQ----HPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPG 145
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
Y+C C GY C DIDEC YC +C N GSF C C G + P + C
Sbjct: 146 SYQCTCPDGYRKIGPE-CVDIDEC--RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
D++EC+ + +PC+ RC N++G F C C GY L
Sbjct: 202 VDVNECD--------------------------MGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 339 DATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX 398
C D +D E + L + C G
Sbjct: 235 HRDGFSCSD----------ID---ECSYSSYLCQYRCVNEPG-----------RFSCHCP 270
Query: 399 KGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRC 436
+G+ L C+D+DEC A C+ TCVN G YRC
Sbjct: 271 QGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 69.7 bits (163), Expect = 2e-11
Identities = 86/316 (27%), Positives = 122/316 (38%), Gaps = 51/316 (16%)
Query: 60 SYTCLCEPGFA-PTAAGYCADVDECAA-DSMCKGG-RCVNSEGSFQCVCEAGYRPTATRG 116
SYT C G+ + +C DV+EC CKG +C+N G + C+ R
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL---------PRS 84
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
A V D E P C PG+ +D +C+ + P+Q
Sbjct: 85 AAVINDLHGE-----GPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQ 138
Query: 177 GSE----LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
Y CP+G K DI+EC C H C NL +RC C+PG+
Sbjct: 139 DCHNLPGSYQCTCPDGYRKIGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLG 195
Query: 232 ADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
+ C D++ECDM C +C N+ G+F C C +G + C DIDEC +
Sbjct: 196 PNNRSCVDVNECDMGAP-CEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYL 253
Query: 291 HYIESDYERGDIPPTFPTRTELAS--------PCDNG--------RCINTHGGFEC---- 330
E G P +L + C++G C+N HGG+ C
Sbjct: 254 CQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTN 313
Query: 331 ECELGYVLDATAQRCL 346
C Y+ + RCL
Sbjct: 314 RCVEPYI-QVSENRCL 328
Score = 61.7 bits (143), Expect = 5e-09
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 58/267 (21%)
Query: 197 DINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
D+NEC +P AC C N GY C+ P + + D+ + G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLCL------PRSAAVINDL--------HGEGPPPP 99
Query: 256 NTAGSFTCVCPEGTRHEPELQ-LCRDIDEC-------EGETETHYIESDYE------RGD 301
CP G +EP+ Q C D+DEC + H + Y+
Sbjct: 100 VPPAQHPNPCPPG--YEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQ 361
I P E RC+N G F C+CE G+ L + C+D +
Sbjct: 158 IGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVN-----------E 206
Query: 362 CEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAE 420
C+ AP Q C S G +G+ DG +C D+DEC+ S+
Sbjct: 207 CDMGAP---CEQRCFNSYG-----------TFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 421 LCAGGTCVNTDGSYRCDCPPGLTLDST 447
LC CVN G + C CP G L +T
Sbjct: 253 LCQ-YRCVNEPGRFSCHCPQGYQLLAT 278
>AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellular
matrix protein protein.
Length = 443
Score = 136 bits (330), Expect = 1e-31
Identities = 96/278 (34%), Positives = 122/278 (43%), Gaps = 42/278 (15%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCLCEPGFA----------- 70
C GYE + CRDV+EC P C+ +C N G Y CL
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 71 ---------PTAAGY-------CADVDEC--AADSMCKGGRCVNSEGSFQCVCEAGYRPT 112
P GY C DVDEC A C N GS+QC C GYR
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYRKI 158
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQ 171
CVD+DEC R C++ RC N PGSFRC+C PGF L + R+C+ + + G C+
Sbjct: 159 GPE--CVDIDEC-RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCE 214
Query: 172 ACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPG-YRCICDPG 227
+ C +G G +DI+EC+ C + C N EPG + C C G
Sbjct: 215 QRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVN-EPGRFSCHCPQG 272
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV 264
Y A LC+DIDEC+ C+ Q C N G + CV
Sbjct: 273 YQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 113 bits (273), Expect = 9e-25
Identities = 59/143 (41%), Positives = 72/143 (50%), Gaps = 9/143 (6%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF-- 69
C N+ G ++C C GY G C D+DECR R C+ RC N GS+ C CEPGF
Sbjct: 140 CHNLSGSYQCTCPDGYRK--IGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQL 194
Query: 70 APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
P C DV+EC + C+ RC NS G+F C C GY +C D+DEC
Sbjct: 195 GPNNRS-CVDVNECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 130 CRNGRCHNTPGSFRCECLPGFTL 152
RC N PG F C C G+ L
Sbjct: 253 LCQYRCVNEPGRFSCHCPQGYQL 275
Score = 109 bits (263), Expect = 1e-23
Identities = 55/136 (40%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C N+ G F C C+PG++ G C DV+EC D C + RC N+ G++ C C G+
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRV 129
G+ C+D+DEC+ S RCVN G F C C GY+ ATR C D+DECE
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATR-LCQDIDECESGAHQ 293
Query: 130 CRNGR-CHNTPGSFRC 144
C + C N G +RC
Sbjct: 294 CSEAQTCVNFHGGYRC 309
Score = 88.6 bits (210), Expect = 4e-17
Identities = 96/339 (28%), Positives = 126/339 (37%), Gaps = 75/339 (22%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNG-RCHNTPGSFRCECLP-GFTLSNDGRTCLG 161
C GY C DV+EC C+ +C N G + C LP + ND
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC--LPRSAAVINDLH---- 92
Query: 162 LKLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGGADINECT-AVPGACPHGSCENLEP 218
G G PAQ + CP G P + D++EC A+ P C NL
Sbjct: 93 ---GEGPPPPVPPAQ----HPNPCPPGYEPDDQDSCVDVDECAQALHDRRPSQDCHNLSG 145
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
Y+C C GY C DIDEC YC +C N GSF C C G + P + C
Sbjct: 146 SYQCTCPDGYRKIGPE-CVDIDEC--RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSC 201
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
D++EC+ + +PC+ RC N++G F C C GY L
Sbjct: 202 VDVNECD--------------------------MGAPCEQ-RCFNSYGTFLCRCHQGYEL 234
Query: 339 DATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX 398
C D +D E + L + C G
Sbjct: 235 HRDGFSCSD----------ID---ECSYSSYLCQYRCVNEPG-----------RFSCHCP 270
Query: 399 KGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRC 436
+G+ L C+D+DEC A C+ TCVN G YRC
Sbjct: 271 QGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 70.5 bits (165), Expect = 1e-11
Identities = 87/316 (27%), Positives = 123/316 (38%), Gaps = 51/316 (16%)
Query: 60 SYTCLCEPGFA-PTAAGYCADVDECAA-DSMCKGG-RCVNSEGSFQCVCEAGYRPTATRG 116
SYT C G+ + +C DV+EC CKG +C+N G + C+ R
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCL---------PRS 84
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
A V D E P C PG+ +D +C+ + P+Q
Sbjct: 85 AAVINDLHGE-----GPPPPVPPAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDRRPSQ 138
Query: 177 G----SELYAVLCPEGPSKDNGGA-DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
S Y CP+G K DI+EC C H C NL +RC C+PG+
Sbjct: 139 DCHNLSGSYQCTCPDGYRKIGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLG 195
Query: 232 ADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
+ C D++ECDM C +C N+ G+F C C +G + C DIDEC +
Sbjct: 196 PNNRSCVDVNECDMGAP-CEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYL 253
Query: 291 HYIESDYERGDIPPTFPTRTELAS--------PCDNG--------RCINTHGGFEC---- 330
E G P +L + C++G C+N HGG+ C
Sbjct: 254 CQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTN 313
Query: 331 ECELGYVLDATAQRCL 346
C Y+ + RCL
Sbjct: 314 RCVEPYI-QVSENRCL 328
Score = 62.1 bits (144), Expect = 4e-09
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 58/267 (21%)
Query: 197 DINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
D+NEC +P AC C N GY C+ P + + D+ + G
Sbjct: 54 DVNECLTIPEACKGEMKCINHYGGYLCL------PRSAAVINDL--------HGEGPPPP 99
Query: 256 NTAGSFTCVCPEGTRHEPELQ-LCRDIDEC-------EGETETHYIESDYE------RGD 301
CP G +EP+ Q C D+DEC + H + Y+
Sbjct: 100 VPPAQHPNPCPPG--YEPDDQDSCVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYRK 157
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQ 361
I P E RC+N G F C+CE G+ L + C+D +
Sbjct: 158 IGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVN-----------E 206
Query: 362 CEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECALSAE 420
C+ AP Q C S G +G+ DG +C D+DEC+ S+
Sbjct: 207 CDMGAP---CEQRCFNSYG-----------TFLCRCHQGYELHRDGFSCSDIDECSYSSY 252
Query: 421 LCAGGTCVNTDGSYRCDCPPGLTLDST 447
LC CVN G + C CP G L +T
Sbjct: 253 LCQ-YRCVNEPGRFSCHCPQGYQLLAT 278
>BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein.
Length = 647
Score = 136 bits (329), Expect = 2e-31
Identities = 113/358 (31%), Positives = 153/358 (42%), Gaps = 43/358 (12%)
Query: 2 TNGGMCTNGICKNIDGGFE-CICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTA 58
+NGG C + D F C+C PG+ G C + D C + C+ G C++
Sbjct: 244 SNGGTCQ--LMPEKDSTFHLCLCPPGFI----GPDCEVNPDNCVSHQ--CQNGGTCQDGL 295
Query: 59 GSYTCLCEPGFAPTAAGYCADVDECAADSM--CK-GGRCVNSEGSFQCVCEAGYRPTATR 115
+YTCLC + T DVDEC C+ GG C NS GSF CVC +G+ T+
Sbjct: 296 DTYTCLCPETW--TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE 353
Query: 116 GACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSNDGRTCLGLKLGWGVSCQAC 173
++D+C C + GSF C C PG T L + CL C
Sbjct: 354 E---NLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTN 410
Query: 174 PAQGSELYAVLCPEGPSKDNGGADINECTAV---PGACPHG-SCENLEPGYRCICDPGYH 229
P GS L LC G S D++EC P C HG SC N + C+C PGY
Sbjct: 411 PLTGSTL--CLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY- 467
Query: 230 PDADGLCR-DIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECE 285
C D +EC + Q G C + +F C+CP EG E E C C
Sbjct: 468 --TGSRCEADHNEC-LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAP-CL 523
Query: 286 GETETHYIESDYERGDIPPTFPTRTE------LASPCDNG-RCINTHGGFECECELGY 336
+ H + + ++ +P TR E +SPC NG +C + G F C+C G+
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGF 581
Score = 117 bits (281), Expect = 1e-25
Identities = 126/440 (28%), Positives = 174/440 (39%), Gaps = 51/440 (11%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCR-NTAGSYTCLCEPGFAPTAAGY 76
F C C PG+ E + D C P C +RGRC +G C C PG+
Sbjct: 101 FLCTCLPGFTG--ERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT---GEQ 153
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNG-R 134
C D C+A+ GG C+ + QC C G+ A DV+EC ++ C G
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS 210
Query: 135 CHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
CHNT GSF+C C G C G +CQ P + S + LCP P
Sbjct: 211 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP--PGF 268
Query: 192 DNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH-QSYC 249
++N V C + G+C++ Y C+C P D D+DEC+ +C
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC-PETWTGWD-CSEDVDECETQGPPHC 326
Query: 250 A-GGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
GG C+N+AGSF CVC GT E L C G T I+ + P
Sbjct: 327 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGST---CIDRVGSFSCLCP- 382
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
P RT L ++ C++ + +C + +T C G C
Sbjct: 383 -PGRTGLLCHLED-MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP--------TCHQD 432
Query: 366 APELLLRQE--CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELC 422
E L+ Q+ C G GS G+ G+ C D +EC LS
Sbjct: 433 LDECLMAQQGPSPCEHG---GSCLNTPGSFNCLCPPGYT---GSRCEADHNEC-LSQPCH 485
Query: 423 AGGTCVNTDGSYRCDCPPGL 442
G TC++ ++ C CPPGL
Sbjct: 486 PGSTCLDLLATFHCLCPPGL 505
Score = 110 bits (264), Expect = 1e-23
Identities = 138/473 (29%), Positives = 189/473 (39%), Gaps = 89/473 (18%)
Query: 5 GMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCR----NT 57
G C G C N G F+C+C G EG C C PR C G C+
Sbjct: 203 GPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCP--PRGCSNGGTCQLMPEKD 256
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ + CLC PGF + D C + GG C + ++ C+C T T
Sbjct: 257 STFHLCLCPPGFIGPDCE--VNPDNCVSHQCQNGGTCQDGLDTYTCLCPE----TWTGWD 310
Query: 118 CV-DVDECEEQRV--CRNG-RCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSC 170
C DVDECE Q CRNG C N+ GSF C C+ G+ + + C+ G +C
Sbjct: 311 CSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG----SCENLEPGYRCICDP 226
GS ++ LCP G + + + C + P C HG S L C+C P
Sbjct: 371 --IDRVGS--FSCLCPPGRTGLLCHLE-DMCLSQP--C-HGDAQCSTNPLTGSTLCLCQP 422
Query: 227 GYHPDADGLC-RDIDECDMHQ---SYCA-GGQCRNTAGSFTCVCP---EGTRHEPE---- 274
GY + C +D+DEC M Q S C GG C NT GSF C+CP G+R E +
Sbjct: 423 GY---SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 479
Query: 275 -LQLCRDIDECEGETET-HYIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECE 331
Q C C T H + G + T ++PC ++ C + GF+C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV-ETNECASAPCLNHADCHDLLNGFQCI 538
Query: 332 CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
C G+ + +D R S GQC+ C C G
Sbjct: 539 CLPGF-SGTRCEEDIDECRSSPCAN--GGQCQDQPGAF----HCKCLPG----------- 580
Query: 392 XXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G C+ +VDEC LS G +C++ G++ C CP G T
Sbjct: 581 ------------FEGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFT 620
Score = 98.3 bits (234), Expect = 5e-20
Identities = 60/190 (31%), Positives = 80/190 (42%), Gaps = 20/190 (10%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
G C N G F C+C PGY G+ C D +EC P C G C + ++ CLC P
Sbjct: 450 GSCLNTPGSFNCLCPPGYT----GSRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPP 503
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
G + +ECA+ C + FQC+C G+ T D+DEC
Sbjct: 504 GLEGQLCE--VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE---DIDECRSS 558
Query: 128 RVCRNGRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
G+C + PG+F C+CLPGF + CL G SC P + L
Sbjct: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPG----AFFCL 614
Query: 185 CPEGPSKDNG 194
CP G + G
Sbjct: 615 CPSGFTGSQG 624
Score = 96.7 bits (230), Expect = 1e-19
Identities = 119/461 (25%), Positives = 169/461 (36%), Gaps = 71/461 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTC 63
C NG +C +C C PG+ EG C RDV+EC +P C +G C NT GS+ C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 220
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRC---VNSEGSFQ-CVCEAGYRPTATRGACV 119
LC G A C GG C + +F C+C G+ V
Sbjct: 221 LCPVGQEGPRCELRA--GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---V 275
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ D C + G C + ++ C C G+ S D C + C
Sbjct: 276 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ V C G + ++++C A A P +C + + C+C PG GL
Sbjct: 336 AGSFHCV-CVSGWGGTSCEENLDDCIAATCA-PGSTCIDRVGSFSCLCPPG----RTGLL 389
Query: 237 RDIDECDMHQSYCAGGQCRNT--AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
+++ + Q QC GS C+C G P +D+DEC
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPG-YSGPTCH--QDLDEC---------- 436
Query: 295 SDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLDN-- 348
++G SPC++ G C+NT G F C C GY +A CL
Sbjct: 437 LMAQQG------------PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPC 484
Query: 349 RRGS-CWRRVVDGQCEAAAPEL------LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GS C + C P L + EC + L GF
Sbjct: 485 HPGSTCLDLLATFHC-LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ G C D+DEC S+ GG C + G++ C C PG
Sbjct: 544 S---GTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKCLPG 580
Score = 90.6 bits (215), Expect = 1e-17
Identities = 127/462 (27%), Positives = 171/462 (37%), Gaps = 81/462 (17%)
Query: 42 CRDNPRVCRRG-RCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCV--- 95
C P C G C + + G TC C PGF C D C +C+ GG C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQALL 84
Query: 96 -------NSEG----SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH-NTPGSFR 143
+S SF C C G+ T R D C + GRCH G +
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 142
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--YAVL---CPEGPSKDNGGADI 198
C C+PG+T G C +L S C G L Y + CP G D+
Sbjct: 143 CSCMPGWT----GEQC---QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 195
Query: 199 NECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCR- 255
NEC PG CP G SC N ++C+C G +G ++ C+ GG C+
Sbjct: 196 NECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQL 251
Query: 256 ---NTAGSFTCVCPEG-----TRHEPE---LQLCRDIDECEG--ETETHYIESDYERGDI 302
+ C+CP G P+ C++ C+ +T T + D
Sbjct: 252 MPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 311
Query: 303 PPTF-PTRTELASPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGS 352
T+ C N G C N+ G F C C G+ + D A C +
Sbjct: 312 SEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG--ST 369
Query: 353 CWRRV--VDGQCEAAAPELLLRQECCC----SVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
C RV C LL E C G A S G++ G
Sbjct: 370 CIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS---G 426
Query: 407 ATC-RDVDECALSAE---LCA-GGTCVNTDGSYRCDCPPGLT 443
TC +D+DEC ++ + C GG+C+NT GS+ C CPPG T
Sbjct: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
Score = 48.0 bits (109), Expect = 7e-05
Identities = 28/79 (35%), Positives = 41/79 (51%), Gaps = 9/79 (11%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTC 63
C NG C++ G F C C PG+E G C+ +VDEC +P C G C + G++ C
Sbjct: 560 CANGGQCQDQPGAFHCKCLPGFE----GPRCQTEVDECLSDP--CPVGASCLDLPGAFFC 613
Query: 64 LCEPGFAPTAAGYCADVDE 82
LC GF + + ++ E
Sbjct: 614 LCPSGFTGSQGRHWKELAE 632
>DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module containing
mucin-like hormone receptor-like 1 protein.
Length = 886
Score = 136 bits (328), Expect = 2e-31
Identities = 85/266 (31%), Positives = 120/266 (45%), Gaps = 41/266 (15%)
Query: 12 CKNIDGGFECICKPGYESGS-------EGALCRDVDECRDNPRVC-RRGRCRNTAGSYTC 63
C N + C CK G+ S + G C+D+DEC +P+ C C+N +G Y C
Sbjct: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
Query: 64 LCEPGF-APTAAGY---------CADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPT 112
C GF +PT + C D++EC S+C + CVNS GS+ C C+ G+
Sbjct: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF--I 164
Query: 113 ATRGACVDVDECEEQRVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW---GV 168
+ C DVDEC + R C + C+NT G++ C C PGF S+ + GLK
Sbjct: 165 SRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDE 224
Query: 169 SCQACPAQGS-----ELYAVLCPEGPSKDNGG----------ADINECTAVPGAC-PHGS 212
+ CP + Y C G + NG DI+EC P C P+
Sbjct: 225 CTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSI 284
Query: 213 CENLEPGYRCICDPGYHPDADGLCRD 238
C N Y C C G+HP+ +G +D
Sbjct: 285 CTNALGSYSCGCIAGFHPNPEGSQKD 310
Score = 104 bits (249), Expect = 7e-22
Identities = 84/280 (30%), Positives = 111/280 (39%), Gaps = 52/280 (18%)
Query: 40 DECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT--------AAGYCADVDECAADSMCKG 91
+ CRD+ C NT SY C C+ GF + C D+DEC+ G
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
Query: 92 --GRCVNSEGSFQCVCEAGY-RPTAT--------RGACVDVDECEEQRVC-RNGRCHNTP 139
C N G ++C C G+ PT +C D++EC VC + C N+
Sbjct: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 152
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-----ELYAVLCPEGPSKDNG 194
GS+ C C GF N TC + +ACP + Y+ C G +G
Sbjct: 153 GSYSCSCQVGFISRNS--TC--EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSG 208
Query: 195 G----------ADINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGL-------- 235
DI+ECT + CP + +C N Y C C PG+ P L
Sbjct: 209 HLSFQGLKASCEDIDECTEM---CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 265
Query: 236 CRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPE 274
CRDIDEC S C C N GS++C C G PE
Sbjct: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPE 305
Score = 95.5 bits (227), Expect = 3e-19
Identities = 77/251 (30%), Positives = 107/251 (42%), Gaps = 46/251 (18%)
Query: 81 DECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRG-------ACVDVDECEEQ-RVCR 131
+ C ++C C N+ S+ C C+ G+ + + C D+DEC + + C
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
Query: 132 -NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---------QACPAQGSEL- 180
N C N G ++C CL GF+ S G + K G SC CP +
Sbjct: 93 PNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKPG-NFSCTDINECLTSSVCPEHSDCVN 150
Query: 181 ----YAVLCPEG-PSKDNGGADINECTAVPGACP-HGSCENLEPGYRCICDPGY-----H 229
Y+ C G S+++ D++EC A P ACP H +C N Y C C+PG+ H
Sbjct: 151 SMGSYSCSCQVGFISRNSTCEDVDEC-ADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 209
Query: 230 PDADGL---CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQL------CR 279
GL C DIDEC + C NT GS+ C C G +L CR
Sbjct: 210 LSFQGLKASCEDIDECT--EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECR 267
Query: 280 DIDECEGETET 290
DIDEC + T
Sbjct: 268 DIDECRQDPST 278
Score = 68.5 bits (160), Expect = 5e-11
Identities = 70/266 (26%), Positives = 98/266 (36%), Gaps = 51/266 (19%)
Query: 197 DINECTAVPGAC-PHGSCENLEPGYRCICDPGYH--------PDADG--LCRDIDECDMH 245
DI+EC+ P C P+ SC+NL Y+C C G+ P G C DI+EC +
Sbjct: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LT 138
Query: 246 QSYCAG-GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
S C C N+ GS++C C G C D+DEC P
Sbjct: 139 SSVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECAD----------------PR 180
Query: 305 TFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEA 364
P ++ C NT G + C C G+ ++ + SC +D +C
Sbjct: 181 ACP---------EHATCNNTVGNYSCFCNPGFE-SSSGHLSFQGLKASC--EDID-ECTE 227
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA- 423
P + C + G + + F G CRD+DEC C
Sbjct: 228 MCP---INSTCTNTPGSYFCTCHPGFAPSNGQL--NFTD-QGVECRDIDECRQDPSTCGP 281
Query: 424 GGTCVNTDGSYRCDCPPGLTLDSTGT 449
C N GSY C C G + G+
Sbjct: 282 NSICTNALGSYSCGCIAGFHPNPEGS 307
Score = 66.5 bits (155), Expect = 2e-10
Identities = 64/246 (26%), Positives = 95/246 (38%), Gaps = 49/246 (19%)
Query: 208 CP-HGSCENLEPGYRCICDPGY-------HPDADGL-CRDIDECDMHQSYCA-GGQCRNT 257
CP + +C N Y C C G+ H G+ C+DIDEC C C+N
Sbjct: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNL 100
Query: 258 AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPC- 316
+G + C C +D T ++ + G+ T +S C
Sbjct: 101 SGRYKCSC---------------LDGFSSPTGNDWVPG--KPGNFSCTDINECLTSSVCP 143
Query: 317 DNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECC 376
++ C+N+ G + C C++G++ +R +C VD E A P +
Sbjct: 144 EHSDCVNSMGSYSCSCQVGFI----------SRNSTC--EDVD---ECADPRAC-PEHAT 187
Query: 377 CSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYR 435
C+ + S F L A+C D+DEC E+C TC NT GSY
Sbjct: 188 CNNTVGNYSCFCNPGFESSSGHLSFQGLK-ASCEDIDECT---EMCPINSTCTNTPGSYF 243
Query: 436 CDCPPG 441
C C PG
Sbjct: 244 CTCHPG 249
Score = 42.7 bits (96), Expect = 0.003
Identities = 61/233 (26%), Positives = 85/233 (36%), Gaps = 61/233 (26%)
Query: 226 PGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG------TRH--EPELQ 276
P P+ G CRD C + + C NT S+ C C +G H +P ++
Sbjct: 24 PTRKPNTKGNNCRDSTLCPAYAT------CTNTVDSYYCACKQGFLSSNGQNHFKDPGVR 77
Query: 277 LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCD-NGRCINTHGGFECECELG 335
C+DIDEC ++ PC N C N G ++C C G
Sbjct: 78 -CKDIDEC-------------------------SQSPQPCGPNSSCKNLSGRYKCSCLDG 111
Query: 336 YVLDATAQRCLDNRRG--SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXX 393
+ T + + G SC + + + PE +C S+G
Sbjct: 112 FS-SPTGNDWVPGKPGNFSC-TDINECLTSSVCPE---HSDCVNSMG-----------SY 155
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
GF + +TC DVDECA TC NT G+Y C C PG S
Sbjct: 156 SCSCQVGFISRN-STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSS 207
>BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein.
Length = 821
Score = 136 bits (328), Expect = 2e-31
Identities = 85/266 (31%), Positives = 120/266 (45%), Gaps = 41/266 (15%)
Query: 12 CKNIDGGFECICKPGYESGS-------EGALCRDVDECRDNPRVC-RRGRCRNTAGSYTC 63
C N + C CK G+ S + G C+D+DEC +P+ C C+N +G Y C
Sbjct: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
Query: 64 LCEPGF-APTAAGY---------CADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPT 112
C GF +PT + C D++EC S+C + CVNS GS+ C C+ G+
Sbjct: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF--I 164
Query: 113 ATRGACVDVDECEEQRVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW---GV 168
+ C DVDEC + R C + C+NT G++ C C PGF S+ + GLK
Sbjct: 165 SRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDE 224
Query: 169 SCQACPAQGS-----ELYAVLCPEGPSKDNGG----------ADINECTAVPGAC-PHGS 212
+ CP + Y C G + NG DI+EC P C P+
Sbjct: 225 CTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSI 284
Query: 213 CENLEPGYRCICDPGYHPDADGLCRD 238
C N Y C C G+HP+ +G +D
Sbjct: 285 CTNALGSYSCGCIAGFHPNPEGSQKD 310
Score = 104 bits (249), Expect = 7e-22
Identities = 84/280 (30%), Positives = 111/280 (39%), Gaps = 52/280 (18%)
Query: 40 DECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT--------AAGYCADVDECAADSMCKG 91
+ CRD+ C NT SY C C+ GF + C D+DEC+ G
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
Query: 92 --GRCVNSEGSFQCVCEAGY-RPTAT--------RGACVDVDECEEQRVC-RNGRCHNTP 139
C N G ++C C G+ PT +C D++EC VC + C N+
Sbjct: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 152
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-----ELYAVLCPEGPSKDNG 194
GS+ C C GF N TC + +ACP + Y+ C G +G
Sbjct: 153 GSYSCSCQVGFISRNS--TC--EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSG 208
Query: 195 G----------ADINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGL-------- 235
DI+ECT + CP + +C N Y C C PG+ P L
Sbjct: 209 HLSFQGLKASCEDIDECTEM---CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 265
Query: 236 CRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPE 274
CRDIDEC S C C N GS++C C G PE
Sbjct: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPE 305
Score = 95.5 bits (227), Expect = 3e-19
Identities = 77/251 (30%), Positives = 107/251 (42%), Gaps = 46/251 (18%)
Query: 81 DECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRG-------ACVDVDECEEQ-RVCR 131
+ C ++C C N+ S+ C C+ G+ + + C D+DEC + + C
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
Query: 132 -NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---------QACPAQGSEL- 180
N C N G ++C CL GF+ S G + K G SC CP +
Sbjct: 93 PNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKPG-NFSCTDINECLTSSVCPEHSDCVN 150
Query: 181 ----YAVLCPEG-PSKDNGGADINECTAVPGACP-HGSCENLEPGYRCICDPGY-----H 229
Y+ C G S+++ D++EC A P ACP H +C N Y C C+PG+ H
Sbjct: 151 SMGSYSCSCQVGFISRNSTCEDVDEC-ADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 209
Query: 230 PDADGL---CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQL------CR 279
GL C DIDEC + C NT GS+ C C G +L CR
Sbjct: 210 LSFQGLKASCEDIDECT--EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECR 267
Query: 280 DIDECEGETET 290
DIDEC + T
Sbjct: 268 DIDECRQDPST 278
Score = 68.5 bits (160), Expect = 5e-11
Identities = 70/266 (26%), Positives = 98/266 (36%), Gaps = 51/266 (19%)
Query: 197 DINECTAVPGAC-PHGSCENLEPGYRCICDPGYH--------PDADG--LCRDIDECDMH 245
DI+EC+ P C P+ SC+NL Y+C C G+ P G C DI+EC +
Sbjct: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LT 138
Query: 246 QSYCAG-GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
S C C N+ GS++C C G C D+DEC P
Sbjct: 139 SSVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECAD----------------PR 180
Query: 305 TFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEA 364
P ++ C NT G + C C G+ ++ + SC +D +C
Sbjct: 181 ACP---------EHATCNNTVGNYSCFCNPGFE-SSSGHLSFQGLKASC--EDID-ECTE 227
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA- 423
P + C + G + + F G CRD+DEC C
Sbjct: 228 MCP---INSTCTNTPGSYFCTCHPGFAPSNGQL--NFTD-QGVECRDIDECRQDPSTCGP 281
Query: 424 GGTCVNTDGSYRCDCPPGLTLDSTGT 449
C N GSY C C G + G+
Sbjct: 282 NSICTNALGSYSCGCIAGFHPNPEGS 307
Score = 66.5 bits (155), Expect = 2e-10
Identities = 64/246 (26%), Positives = 95/246 (38%), Gaps = 49/246 (19%)
Query: 208 CP-HGSCENLEPGYRCICDPGY-------HPDADGL-CRDIDECDMHQSYCA-GGQCRNT 257
CP + +C N Y C C G+ H G+ C+DIDEC C C+N
Sbjct: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNL 100
Query: 258 AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPC- 316
+G + C C +D T ++ + G+ T +S C
Sbjct: 101 SGRYKCSC---------------LDGFSSPTGNDWVPG--KPGNFSCTDINECLTSSVCP 143
Query: 317 DNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECC 376
++ C+N+ G + C C++G++ +R +C VD E A P +
Sbjct: 144 EHSDCVNSMGSYSCSCQVGFI----------SRNSTC--EDVD---ECADPRAC-PEHAT 187
Query: 377 CSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYR 435
C+ + S F L A+C D+DEC E+C TC NT GSY
Sbjct: 188 CNNTVGNYSCFCNPGFESSSGHLSFQGLK-ASCEDIDECT---EMCPINSTCTNTPGSYF 243
Query: 436 CDCPPG 441
C C PG
Sbjct: 244 CTCHPG 249
Score = 42.7 bits (96), Expect = 0.003
Identities = 61/233 (26%), Positives = 85/233 (36%), Gaps = 61/233 (26%)
Query: 226 PGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG------TRH--EPELQ 276
P P+ G CRD C + + C NT S+ C C +G H +P ++
Sbjct: 24 PTRKPNTKGNNCRDSTLCPAYAT------CTNTVDSYYCACKQGFLSSNGQNHFKDPGVR 77
Query: 277 LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCD-NGRCINTHGGFECECELG 335
C+DIDEC ++ PC N C N G ++C C G
Sbjct: 78 -CKDIDEC-------------------------SQSPQPCGPNSSCKNLSGRYKCSCLDG 111
Query: 336 YVLDATAQRCLDNRRG--SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXX 393
+ T + + G SC + + + PE +C S+G
Sbjct: 112 FS-SPTGNDWVPGKPGNFSC-TDINECLTSSVCPE---HSDCVNSMG-----------SY 155
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
GF + +TC DVDECA TC NT G+Y C C PG S
Sbjct: 156 SCSCQVGFISRN-STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSS 207
>AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane helix
receptor protein.
Length = 929
Score = 136 bits (328), Expect = 2e-31
Identities = 85/266 (31%), Positives = 120/266 (45%), Gaps = 41/266 (15%)
Query: 12 CKNIDGGFECICKPGYESGS-------EGALCRDVDECRDNPRVC-RRGRCRNTAGSYTC 63
C N + C CK G+ S + G C+D+DEC +P+ C C+N +G Y C
Sbjct: 65 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 124
Query: 64 LCEPGF-APTAAGY---------CADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPT 112
C GF +PT + C D++EC S+C + CVNS GS+ C C+ G+
Sbjct: 125 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF--I 182
Query: 113 ATRGACVDVDECEEQRVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW---GV 168
+ C DVDEC + R C + C+NT G++ C C PGF S+ + GLK
Sbjct: 183 SRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDE 242
Query: 169 SCQACPAQGS-----ELYAVLCPEGPSKDNGG----------ADINECTAVPGAC-PHGS 212
+ CP + Y C G + NG DI+EC P C P+
Sbjct: 243 CTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSI 302
Query: 213 CENLEPGYRCICDPGYHPDADGLCRD 238
C N Y C C G+HP+ +G +D
Sbjct: 303 CTNALGSYSCGCIAGFHPNPEGSQKD 328
Score = 104 bits (249), Expect = 7e-22
Identities = 84/280 (30%), Positives = 111/280 (39%), Gaps = 52/280 (18%)
Query: 40 DECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPT--------AAGYCADVDECAADSMCKG 91
+ CRD+ C NT SY C C+ GF + C D+DEC+ G
Sbjct: 51 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 110
Query: 92 --GRCVNSEGSFQCVCEAGY-RPTAT--------RGACVDVDECEEQRVC-RNGRCHNTP 139
C N G ++C C G+ PT +C D++EC VC + C N+
Sbjct: 111 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 170
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-----ELYAVLCPEGPSKDNG 194
GS+ C C GF N TC + +ACP + Y+ C G +G
Sbjct: 171 GSYSCSCQVGFISRNS--TC--EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSG 226
Query: 195 G----------ADINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGL-------- 235
DI+ECT + CP + +C N Y C C PG+ P L
Sbjct: 227 HLSFQGLKASCEDIDECTEM---CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 283
Query: 236 CRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPE 274
CRDIDEC S C C N GS++C C G PE
Sbjct: 284 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPE 323
Score = 95.5 bits (227), Expect = 3e-19
Identities = 77/251 (30%), Positives = 107/251 (42%), Gaps = 46/251 (18%)
Query: 81 DECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRG-------ACVDVDECEEQ-RVCR 131
+ C ++C C N+ S+ C C+ G+ + + C D+DEC + + C
Sbjct: 51 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 110
Query: 132 -NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---------QACPAQGSEL- 180
N C N G ++C CL GF+ S G + K G SC CP +
Sbjct: 111 PNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKPG-NFSCTDINECLTSSVCPEHSDCVN 168
Query: 181 ----YAVLCPEG-PSKDNGGADINECTAVPGACP-HGSCENLEPGYRCICDPGY-----H 229
Y+ C G S+++ D++EC A P ACP H +C N Y C C+PG+ H
Sbjct: 169 SMGSYSCSCQVGFISRNSTCEDVDEC-ADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 227
Query: 230 PDADGL---CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQL------CR 279
GL C DIDEC + C NT GS+ C C G +L CR
Sbjct: 228 LSFQGLKASCEDIDECT--EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECR 285
Query: 280 DIDECEGETET 290
DIDEC + T
Sbjct: 286 DIDECRQDPST 296
Score = 68.5 bits (160), Expect = 5e-11
Identities = 70/266 (26%), Positives = 98/266 (36%), Gaps = 51/266 (19%)
Query: 197 DINECTAVPGAC-PHGSCENLEPGYRCICDPGYH--------PDADG--LCRDIDECDMH 245
DI+EC+ P C P+ SC+NL Y+C C G+ P G C DI+EC +
Sbjct: 98 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LT 156
Query: 246 QSYCAG-GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
S C C N+ GS++C C G C D+DEC P
Sbjct: 157 SSVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECAD----------------PR 198
Query: 305 TFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEA 364
P ++ C NT G + C C G+ ++ + SC +D +C
Sbjct: 199 ACP---------EHATCNNTVGNYSCFCNPGFE-SSSGHLSFQGLKASC--EDID-ECTE 245
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA- 423
P + C + G + + F G CRD+DEC C
Sbjct: 246 MCP---INSTCTNTPGSYFCTCHPGFAPSNGQL--NFTD-QGVECRDIDECRQDPSTCGP 299
Query: 424 GGTCVNTDGSYRCDCPPGLTLDSTGT 449
C N GSY C C G + G+
Sbjct: 300 NSICTNALGSYSCGCIAGFHPNPEGS 325
Score = 66.5 bits (155), Expect = 2e-10
Identities = 64/246 (26%), Positives = 95/246 (38%), Gaps = 49/246 (19%)
Query: 208 CP-HGSCENLEPGYRCICDPGY-------HPDADGL-CRDIDECDMHQSYCA-GGQCRNT 257
CP + +C N Y C C G+ H G+ C+DIDEC C C+N
Sbjct: 59 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNL 118
Query: 258 AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPC- 316
+G + C C +D T ++ + G+ T +S C
Sbjct: 119 SGRYKCSC---------------LDGFSSPTGNDWVPG--KPGNFSCTDINECLTSSVCP 161
Query: 317 DNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECC 376
++ C+N+ G + C C++G++ +R +C VD E A P +
Sbjct: 162 EHSDCVNSMGSYSCSCQVGFI----------SRNSTC--EDVD---ECADPRAC-PEHAT 205
Query: 377 CSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYR 435
C+ + S F L A+C D+DEC E+C TC NT GSY
Sbjct: 206 CNNTVGNYSCFCNPGFESSSGHLSFQGLK-ASCEDIDECT---EMCPINSTCTNTPGSYF 261
Query: 436 CDCPPG 441
C C PG
Sbjct: 262 CTCHPG 267
Score = 42.7 bits (96), Expect = 0.003
Identities = 61/233 (26%), Positives = 85/233 (36%), Gaps = 61/233 (26%)
Query: 226 PGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG------TRH--EPELQ 276
P P+ G CRD C + + C NT S+ C C +G H +P ++
Sbjct: 42 PTRKPNTKGNNCRDSTLCPAYAT------CTNTVDSYYCACKQGFLSSNGQNHFKDPGVR 95
Query: 277 LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCD-NGRCINTHGGFECECELG 335
C+DIDEC ++ PC N C N G ++C C G
Sbjct: 96 -CKDIDEC-------------------------SQSPQPCGPNSSCKNLSGRYKCSCLDG 129
Query: 336 YVLDATAQRCLDNRRG--SCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXX 393
+ T + + G SC + + + PE +C S+G
Sbjct: 130 FS-SPTGNDWVPGKPGNFSC-TDINECLTSSVCPE---HSDCVNSMG-----------SY 173
Query: 394 XXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
GF + +TC DVDECA TC NT G+Y C C PG S
Sbjct: 174 SCSCQVGFISRN-STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSS 225
>AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA
sequence from clone GS1-174L6 on chromosome 1. ).
Length = 240
Score = 134 bits (325), Expect = 5e-31
Identities = 64/148 (43%), Positives = 88/148 (59%), Gaps = 10/148 (6%)
Query: 17 GGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTC--LCEPGFAPTA 73
G F C C+PGY+ +G C DV+ECR N VCR + C+NT G Y C LC G
Sbjct: 3 GSFHCGCEPGYQL--KGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMTKAE 58
Query: 74 AGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCR 131
G C D+DEC + C+ + C N+ GS++CVC GYR C+D+DECE C+
Sbjct: 59 NGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECENTDACQ 118
Query: 132 NGRCHNTPGSFRCECLPGFTLSNDGRTC 159
+ C NT GS++C C PG+ L+++G+TC
Sbjct: 119 H-ECKNTFGSYQCICPPGYQLTHNGKTC 145
Score = 119 bits (287), Expect = 2e-26
Identities = 63/158 (39%), Positives = 80/158 (50%), Gaps = 11/158 (6%)
Query: 12 CKNIDGGFECI--CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
CKN GG++CI C G G C D+DEC+D CR + C NT GSY C+C G
Sbjct: 37 CKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRG 95
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+ G C D+DEC C+ C N+ GS+QC+C GY+ T C D+DEC EQ
Sbjct: 96 YRSQGVGRPCMDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQ 154
Query: 128 RV-C-RNGRCHNTPGSFRC---ECLPGFTLSNDGRTCL 160
V C N C N GS++C C P + CL
Sbjct: 155 NVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCL 192
Score = 102 bits (244), Expect = 3e-21
Identities = 67/205 (32%), Positives = 92/205 (44%), Gaps = 17/205 (8%)
Query: 59 GSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCV--CEAGYRPTATRG 116
GS+ C CEPG+ C DV+EC + C N+ G ++C+ C G A G
Sbjct: 3 GSFHCGCEPGYQ-LKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK-AENG 60
Query: 117 ACVDVDECEE-QRVCR-NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQAC 173
C+D+DEC++ CR N C NT GS+RC C G+ GR C+ + +CQ
Sbjct: 61 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECENTDACQHE 120
Query: 174 PAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGAC-PHGSCENLEPGYRCI---CDP 226
Y +CP G + G DI+EC C P+ C N+ Y+CI C P
Sbjct: 121 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPP 180
Query: 227 GYHPD-ADGLCRDIDECDMHQSYCA 250
Y D G C + C + CA
Sbjct: 181 NYQRDPVSGFC--LKNCPPNDLECA 203
Score = 97.5 bits (232), Expect = 9e-20
Identities = 58/153 (37%), Positives = 75/153 (49%), Gaps = 12/153 (7%)
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSC---QACP-AQGSELYAVLCPEGPSKDNGG 195
GSF C C PG+ L GR C+ + C Q C +G LCP G +K G
Sbjct: 3 GSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 60
Query: 196 A--DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAG 251
DI+EC C + CEN YRC+C GY G C DIDEC+ + C
Sbjct: 61 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECE-NTDACQH 119
Query: 252 GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
+C+NT GS+ C+CP G + + C+DIDEC
Sbjct: 120 -ECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 151
Score = 97.1 bits (231), Expect = 1e-19
Identities = 47/117 (40%), Positives = 63/117 (53%), Gaps = 8/117 (6%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
N IC+N G + C+C GY S G C D+DEC +N C+ C+NT GSY C+C PG
Sbjct: 78 NQICENTRGSYRCVCPRGYRSQGVGRPCMDIDEC-ENTDACQH-ECKNTFGSYQCICPPG 135
Query: 69 FAPTAAG-YCADVDECAADSM-CKGGR-CVNSEGSFQCV---CEAGYRPTATRGACV 119
+ T G C D+DEC ++ C R C N GS+QC+ C Y+ G C+
Sbjct: 136 YQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCL 192
Score = 77.8 bits (183), Expect = 7e-14
Identities = 41/93 (44%), Positives = 48/93 (51%), Gaps = 6/93 (6%)
Query: 197 DINECTAVPGAC-PHGSCENLEPGYRCI--CDPGYHPDADGLCRDIDECDMHQSYCAGGQ 253
D+NEC C P C+N GY+CI C G +G C DIDEC C Q
Sbjct: 22 DVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQ 79
Query: 254 -CRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
C NT GS+ CVCP G R + + C DIDECE
Sbjct: 80 ICENTRGSYRCVCPRGYRSQGVGRPCMDIDECE 112
Score = 61.3 bits (142), Expect = 7e-09
Identities = 63/233 (27%), Positives = 83/233 (35%), Gaps = 59/233 (25%)
Query: 220 YRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCV--CPEGTRHEPELQ 276
+ C C+PGY C D++EC Q+ C Q C+NT G + C+ CP G + E
Sbjct: 5 FHCGCEPGYQLKGRK-CMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMT-KAENG 60
Query: 277 LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGY 336
C DIDEC+ T + Y N C NT G + C C GY
Sbjct: 61 TCIDIDECKDGTH----QCRY--------------------NQICENTRGSYRCVCPRGY 96
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
+ C+D C C+ +C C G
Sbjct: 97 RSQGVGRPCMD--IDECEN---TDACQHECKNTFGSYQCICPPGYQ-------------- 137
Query: 397 XXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRC---DCPPGLTLD 445
+G TC+D+DEC C C N GSY+C CPP D
Sbjct: 138 -----LTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRD 185
Score = 46.4 bits (105), Expect = 2e-04
Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPGLTLDSTG 448
G K + TC D+DEC C C NT GSYRC CP G G
Sbjct: 53 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG 102
Score = 44.0 bits (99), Expect = 0.001
Identities = 20/43 (46%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C D+DEC + + C C NT GSY+C CPPG L G
Sbjct: 102 GRPCMDIDECE-NTDACQH-ECKNTFGSYQCICPPGYQLTHNG 142
Score = 35.5 bits (78), Expect = 0.39
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 5/50 (10%)
Query: 403 KLDGATCRDVDECALSAELCAGGT-CVNTDGSYRCD--CPPGLTLDSTGT 449
+L G C DV+EC +C C NT G Y+C CP G+T GT
Sbjct: 14 QLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT 61
>BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein.
Length = 807
Score = 133 bits (322), Expect = 1e-30
Identities = 103/372 (27%), Positives = 150/372 (40%), Gaps = 37/372 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C NI G + C C G+ +G C DVDEC +N C+ C N GSY
Sbjct: 95 NGG-CVHD-CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYE 151
Query: 63 CLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVN-----SEGSFQCVCEAGYRPTATRG 116
C C+ GF + + C E M K C + GS C C G+ +
Sbjct: 152 CCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQR 211
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
C+ C C +T C C P + + DGR+CL + +
Sbjct: 212 DCILT--CNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCL--------EREDTVLE 261
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-L 235
+E +G + + C G C +C++ G C C G+ DG
Sbjct: 262 VTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDR-TCKDTSTGVHCSCPVGFTLQLDGKT 320
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIES 295
C+DIDEC C C+N GSF C C +G + + + C+D+DEC + +
Sbjct: 321 CKDIDECQTRNGGC-DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCI 379
Query: 296 DY--------ERGDIPPTFPTRTELASPC--DNGR----CINTHGGFECECELGYVLDAT 341
++ RG F T + C +NG C+NT G +EC+C GY L
Sbjct: 380 NHPGTFACACNRGYTLYGF-THCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWN 438
Query: 342 AQRCLDNRRGSC 353
+ C+ + SC
Sbjct: 439 KKDCVASCDLSC 450
Score = 118 bits (283), Expect = 6e-26
Identities = 108/397 (27%), Positives = 156/397 (39%), Gaps = 48/397 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
+ +C+N ++C CKPGY+ EG C D+DEC + C N G+Y C C G
Sbjct: 59 DALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDG 116
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
F G+ C DVDEC ++ CVN GS++C C+ G+ + + C + EE
Sbjct: 117 FMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC--IHRSEEG 174
Query: 128 RVCRNGR------CHNTP-GSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQACPAQGSE 179
C N C P GS CEC PGF L+ + R C L G G +C
Sbjct: 175 LSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTADG 234
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
P+ +G + + V E E + D L +
Sbjct: 235 PECSCHPQYKMHTDGRSCLEREDTV--------LEVTESNTTSVVDGDKRVKRRLL---M 283
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE--THY---IE 294
+ C ++ C C++T+ C CP G + + + C+DIDEC+ H+ I
Sbjct: 284 ETCAVNNGGC-DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIV 342
Query: 295 SDYERGDIPPTFPTRTE-----------LASPCDNGRCINTHGGFECECELGYVLDATAQ 343
++ G F T+ L CD+ CIN G F C C GY L
Sbjct: 343 GSFDCG-CKKGFKLLTDEKSCQDVDECSLDRTCDHS-CINHPGTFACACNRGYTLYGFT- 399
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C D S + +G C+ + EC C G
Sbjct: 400 HCGDTNECS----INNGGCQQVCVNTVGSYECQCHPG 432
Score = 109 bits (262), Expect = 2e-23
Identities = 114/409 (27%), Positives = 162/409 (39%), Gaps = 49/409 (11%)
Query: 73 AAGYCADVDECA--ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC--EEQR 128
AAG DVDECA D C N+ S++C C+ GY+ + C D+DEC E
Sbjct: 39 AAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNELNG 96
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSELYAVLCP 186
C + C N PG++RC C GF L++DG CL + L CQ Y C
Sbjct: 97 GCVHD-CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCK 155
Query: 187 EG-PSKDNGGADIN------ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
EG DN I+ C C H E C C PG+ L ++
Sbjct: 156 EGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFE-----LAKNQ 210
Query: 240 DECDMHQSYCAGG---QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE-TE---THY 292
+C + ++ GG C +TA C C + + + C + ++ E TE T
Sbjct: 211 RDCILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSV 270
Query: 293 IESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD----- 347
++ D +R T CD C +T G C C +G+ L + C D
Sbjct: 271 VDGD-KRVKRRLLMETCAVNNGGCDR-TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQ 328
Query: 348 NRRGSC---WRRVV---DGQCEAAAPELLLRQECC-----CSVGLAWG-SXXXXXXXXXX 395
R G C + +V D C+ +LL ++ C CS+ S
Sbjct: 329 TRNGGCDHFCKNIVGSFDCGCKKGF-KLLTDEKSCQDVDECSLDRTCDHSCINHPGTFAC 387
Query: 396 XXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+G+ C D +EC+++ C CVNT GSY C C PG L
Sbjct: 388 ACNRGYTLYGFTHCGDTNECSINNGGCQ-QVCVNTVGSYECQCHPGYKL 435
Score = 86.6 bits (205), Expect = 2e-16
Identities = 42/118 (35%), Positives = 62/118 (52%), Gaps = 3/118 (2%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
T G C + CKNI G F+C CK G++ ++ C+DVDEC R C C N G++
Sbjct: 329 TRNGGCDH-FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDEC-SLDRTCDHS-CINHPGTF 385
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C G+ +C D +EC+ ++ CVN+ GS++C C GY+ + CV
Sbjct: 386 ACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCV 443
Score = 60.9 bits (141), Expect = 9e-09
Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 3/107 (2%)
Query: 180 LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR 237
L A P G + G D++EC C + C+N Y+C C PGY + C
Sbjct: 27 LLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ-CE 85
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
DIDEC + C N G++ C C +G + C D+DEC
Sbjct: 86 DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDEC 132
Score = 37.5 bits (83), Expect = 0.097
Identities = 16/44 (36%), Positives = 20/44 (45%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+G C D+DEC C+N G+YRC C G L G
Sbjct: 80 EGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDG 123
>AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ16792 fis, clone TBAES2007379, moderately
similar to Homo sapiens signal peptide, CUB domain,
EGF-like 2 (SCUBE2). ).
Length = 682
Score = 133 bits (322), Expect = 1e-30
Identities = 103/372 (27%), Positives = 150/372 (40%), Gaps = 37/372 (9%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C NI G + C C G+ +G C DVDEC +N C+ C N GSY
Sbjct: 95 NGG-CVHD-CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYE 151
Query: 63 CLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVN-----SEGSFQCVCEAGYRPTATRG 116
C C+ GF + + C E M K C + GS C C G+ +
Sbjct: 152 CCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQR 211
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
C+ C C +T C C P + + DGR+CL + +
Sbjct: 212 DCILT--CNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCL--------EREDTVLE 261
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-L 235
+E +G + + C G C +C++ G C C G+ DG
Sbjct: 262 VTESNTTSVVDGDKRVKRQLLMETCAVNNGGCDR-TCKDTSTGVHCSCPVGFTLQLDGKT 320
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIES 295
C+DIDEC C C+N GSF C C +G + + + C+D+DEC + +
Sbjct: 321 CKDIDECQTRNGGC-DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCI 379
Query: 296 DY--------ERGDIPPTFPTRTELASPC--DNGR----CINTHGGFECECELGYVLDAT 341
++ RG F T + C +NG C+NT G +EC+C GY L
Sbjct: 380 NHPGTFACACNRGYTLYGF-THCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWN 438
Query: 342 AQRCLDNRRGSC 353
+ C+ + SC
Sbjct: 439 KKDCVASCDLSC 450
Score = 118 bits (285), Expect = 3e-26
Identities = 108/397 (27%), Positives = 156/397 (39%), Gaps = 48/397 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
+ +C+N ++C CKPGY+ EG C D+DEC + C N G+Y C C G
Sbjct: 59 DALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDG 116
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
F G+ C DVDEC ++ CVN GS++C C+ G+ + + C + EE
Sbjct: 117 FMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC--IHRSEEG 174
Query: 128 RVCRNGR------CHNTP-GSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQACPAQGSE 179
C N C P GS CEC PGF L+ + R C L G G +C
Sbjct: 175 LSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTADG 234
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
P+ +G + + V E E + D L +
Sbjct: 235 PECSCHPQYKMHTDGRSCLEREDTV--------LEVTESNTTSVVDGDKRVKRQLL---M 283
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE--THY---IE 294
+ C ++ C C++T+ C CP G + + + C+DIDEC+ H+ I
Sbjct: 284 ETCAVNNGGC-DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIV 342
Query: 295 SDYERGDIPPTFPTRTE-----------LASPCDNGRCINTHGGFECECELGYVLDATAQ 343
++ G F T+ L CD+ CIN G F C C GY L
Sbjct: 343 GSFDCG-CKKGFKLLTDEKSCQDVDECSLDRTCDHS-CINHPGTFACACNRGYTLYGFT- 399
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C D S + +G C+ + EC C G
Sbjct: 400 HCGDTNECS----INNGGCQQVCVNTVGSYECQCHPG 432
Score = 109 bits (263), Expect = 1e-23
Identities = 114/409 (27%), Positives = 162/409 (39%), Gaps = 49/409 (11%)
Query: 73 AAGYCADVDECA--ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC--EEQR 128
AAG DVDECA D C N+ S++C C+ GY+ + C D+DEC E
Sbjct: 39 AAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNELNG 96
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSELYAVLCP 186
C + C N PG++RC C GF L++DG CL + L CQ Y C
Sbjct: 97 GCVHD-CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCK 155
Query: 187 EG-PSKDNGGADIN------ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
EG DN I+ C C H E C C PG+ L ++
Sbjct: 156 EGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFE-----LAKNQ 210
Query: 240 DECDMHQSYCAGG---QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE-TE---THY 292
+C + ++ GG C +TA C C + + + C + ++ E TE T
Sbjct: 211 RDCILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSV 270
Query: 293 IESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD----- 347
++ D +R T CD C +T G C C +G+ L + C D
Sbjct: 271 VDGD-KRVKRQLLMETCAVNNGGCDR-TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQ 328
Query: 348 NRRGSC---WRRVV---DGQCEAAAPELLLRQECC-----CSVGLAWG-SXXXXXXXXXX 395
R G C + +V D C+ +LL ++ C CS+ S
Sbjct: 329 TRNGGCDHFCKNIVGSFDCGCKKGF-KLLTDEKSCQDVDECSLDRTCDHSCINHPGTFAC 387
Query: 396 XXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+G+ C D +EC+++ C CVNT GSY C C PG L
Sbjct: 388 ACNRGYTLYGFTHCGDTNECSINNGGCQ-QVCVNTVGSYECQCHPGYKL 435
Score = 86.6 bits (205), Expect = 2e-16
Identities = 42/118 (35%), Positives = 62/118 (52%), Gaps = 3/118 (2%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
T G C + CKNI G F+C CK G++ ++ C+DVDEC R C C N G++
Sbjct: 329 TRNGGCDH-FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDEC-SLDRTCDHS-CINHPGTF 385
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C G+ +C D +EC+ ++ CVN+ GS++C C GY+ + CV
Sbjct: 386 ACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCV 443
Score = 60.9 bits (141), Expect = 9e-09
Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 3/107 (2%)
Query: 180 LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR 237
L A P G + G D++EC C + C+N Y+C C PGY + C
Sbjct: 27 LLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ-CE 85
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
DIDEC + C N G++ C C +G + C D+DEC
Sbjct: 86 DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDEC 132
Score = 37.5 bits (83), Expect = 0.097
Identities = 16/44 (36%), Positives = 20/44 (45%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+G C D+DEC C+N G+YRC C G L G
Sbjct: 80 EGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDG 123
>AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein.
Length = 439
Score = 133 bits (322), Expect = 1e-30
Identities = 98/278 (35%), Positives = 129/278 (46%), Gaps = 46/278 (16%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCL----------------- 64
C GY ++ A CRDV+EC P C+ +C N G Y CL
Sbjct: 39 CTDGY---TQTANCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 95
Query: 65 ------CEP---GFAPTAAGYCADVDECA-ADSMCKGGR-CVNSEGSFQCVCEAGYRPTA 113
+P G+ P C DVDECA A C+ + C N GS+QC C GYR
Sbjct: 96 PVPPVNTQPLPTGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIG 155
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQA 172
CVD+DEC R C++ RC N PGSFRC+C PGF L + R+C+ + + G C+
Sbjct: 156 PE--CVDIDECR-YRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQ 211
Query: 173 CPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPG-YRCICDPGY 228
+ C +G G +DI+EC+ C + C N EPG + C C GY
Sbjct: 212 RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-RCVN-EPGRFSCHCPQGY 269
Query: 229 HPDADGLCRDIDECD--MHQSYCAGGQCRNTAGSFTCV 264
A LC+DIDEC+ HQ + C N G + CV
Sbjct: 270 QLLATRLCQDIDECESGAHQ-WSEAQTCVNFHGGYRCV 306
Score = 113 bits (272), Expect = 1e-24
Identities = 59/143 (41%), Positives = 72/143 (50%), Gaps = 9/143 (6%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF-- 69
C N+ G ++C C GY G C D+DECR R C+ RC N GS+ C CEPGF
Sbjct: 136 CHNLPGSYQCTCPDGYRK--IGPECVDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQL 190
Query: 70 APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
P C DV+EC + C+ RC NS G+F C C GY +C D+DEC
Sbjct: 191 GPNNRS-CVDVNECDMGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSY 248
Query: 130 CRNGRCHNTPGSFRCECLPGFTL 152
RC N PG F C C G+ L
Sbjct: 249 LCQYRCVNEPGRFSCHCPQGYQL 271
Score = 107 bits (258), Expect = 6e-23
Identities = 54/136 (39%), Positives = 72/136 (52%), Gaps = 6/136 (4%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C N+ G F C C+PG++ G C DV+EC D C + RC N+ G++ C C G+
Sbjct: 173 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGYEL 230
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE--QR 128
G+ C+D+DEC+ S RCVN G F C C GY+ ATR C D+DECE +
Sbjct: 231 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATR-LCQDIDECESGAHQ 289
Query: 129 VCRNGRCHNTPGSFRC 144
C N G +RC
Sbjct: 290 WSEAQTCVNFHGGYRC 305
Score = 81.4 bits (192), Expect = 6e-15
Identities = 95/339 (28%), Positives = 123/339 (36%), Gaps = 79/339 (23%)
Query: 105 CEAGYRPTATRGACVDVDECEE-QRVCRNG-RCHNTPGSFRCECLP-GFTLSNDGRTCLG 161
C GY TA C DV+EC C+ +C N G + C LP + ND
Sbjct: 39 CTDGYTQTAN---CRDVNECLTIPEACKGEMKCINHYGGYLC--LPRSAAVINDLH---- 89
Query: 162 LKLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGGADINECTAVPGAC-PHGSCENLEP 218
G G P L P G P + D++EC C P C NL
Sbjct: 90 ---GEGPPPPVPPVNTQPL-----PTGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPG 141
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLC 278
Y+C C GY C DIDEC YC +C N GSF C C G + P + C
Sbjct: 142 SYQCTCPDGYRKIGPE-CVDIDEC--RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSC 197
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVL 338
D++EC+ + +PC+ RC N++G F C C GY L
Sbjct: 198 VDVNECD--------------------------MGAPCEQ-RCFNSYGTFLCRCHQGYEL 230
Query: 339 DATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXX 398
C D +D E + L + C G
Sbjct: 231 HRDGFSCSD----------ID---ECSYSSYLCQYRCVNEPG-----------RFSCHCP 266
Query: 399 KGFAKLDGATCRDVDECALSA-ELCAGGTCVNTDGSYRC 436
+G+ L C+D+DEC A + TCVN G YRC
Sbjct: 267 QGYQLLATRLCQDIDECESGAHQWSEAQTCVNFHGGYRC 305
Score = 61.3 bits (142), Expect = 7e-09
Identities = 72/279 (25%), Positives = 103/279 (36%), Gaps = 59/279 (21%)
Query: 185 CPEGPSKDNGGADINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGLCRDIDECD 243
C +G ++ D+NEC +P AC C N GY C+ P + + D+
Sbjct: 39 CTDGYTQTANCRDVNECLTIPEACKGEMKCINHYGGYLCL------PRSAAVINDLH--- 89
Query: 244 MHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQ-LCRDIDEC-------EGETETHYIES 295
G+ P T +EP+ Q C D+DEC + H +
Sbjct: 90 --------GEGPPPPVPPVNTQPLPTGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPG 141
Query: 296 DYE------RGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
Y+ I P E RC+N G F C+CE G+ L + C+D
Sbjct: 142 SYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVN 201
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGAT 408
+C+ AP Q C S G +G+ DG +
Sbjct: 202 -----------ECDMGAP---CEQRCFNSYG-----------TFLCRCHQGYELHRDGFS 236
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
C D+DEC+ S+ LC CVN G + C CP G L +T
Sbjct: 237 CSDIDECSYSSYLCQ-YRCVNEPGRFSCHCPQGYQLLAT 274
>AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens
cDNA FLJ41044 fis, clone NT2RP7000466, highly similar
to Mus musculus CUB domain and EGF-like repeat
containing 1 (Cegf1). ).
Length = 971
Score = 133 bits (321), Expect = 1e-30
Identities = 101/366 (27%), Positives = 148/366 (40%), Gaps = 37/366 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C NI G + C C G+ +G C DVDEC +N C+ C N GSY
Sbjct: 95 NGG-CVHD-CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYE 151
Query: 63 CLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVN-----SEGSFQCVCEAGYRPTATRG 116
C C+ GF + + C E M K C + GS C C G+ +
Sbjct: 152 CCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQR 211
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
C+ C C +T C C P + + DGR+CL + +
Sbjct: 212 DCILT--CNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCL--------EREDTVLE 261
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-L 235
+E +G + + C G C +C++ G C C G+ DG
Sbjct: 262 VTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDR-TCKDTSTGVHCSCPVGFTLQLDGKT 320
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIES 295
C+DIDEC C C+N GSF C C +G + + + C+D+DEC + +
Sbjct: 321 CKDIDECQTRNGGC-DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCI 379
Query: 296 DY--------ERGDIPPTFPTRTELASPC--DNGR----CINTHGGFECECELGYVLDAT 341
++ RG F T + C +NG C+NT G +EC+C GY L
Sbjct: 380 NHPGTFACACNRGYTLYGF-THCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWN 438
Query: 342 AQRCLD 347
+ C++
Sbjct: 439 KKDCVE 444
Score = 118 bits (283), Expect = 6e-26
Identities = 108/397 (27%), Positives = 156/397 (39%), Gaps = 48/397 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
+ +C+N ++C CKPGY+ EG C D+DEC + C N G+Y C C G
Sbjct: 59 DALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDG 116
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
F G+ C DVDEC ++ CVN GS++C C+ G+ + + C + EE
Sbjct: 117 FMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC--IHRSEEG 174
Query: 128 RVCRNGR------CHNTP-GSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQACPAQGSE 179
C N C P GS CEC PGF L+ + R C L G G +C
Sbjct: 175 LSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTADG 234
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
P+ +G + + V E E + D L +
Sbjct: 235 PECSCHPQYKMHTDGRSCLEREDTV--------LEVTESNTTSVVDGDKRVKRRLL---M 283
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE--THY---IE 294
+ C ++ C C++T+ C CP G + + + C+DIDEC+ H+ I
Sbjct: 284 ETCAVNNGGC-DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIV 342
Query: 295 SDYERGDIPPTFPTRTE-----------LASPCDNGRCINTHGGFECECELGYVLDATAQ 343
++ G F T+ L CD+ CIN G F C C GY L
Sbjct: 343 GSFDCG-CKKGFKLLTDEKSCQDVDECSLDRTCDHS-CINHPGTFACACNRGYTLYGFT- 399
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C D S + +G C+ + EC C G
Sbjct: 400 HCGDTNECS----INNGGCQQVCVNTVGSYECQCHPG 432
Score = 109 bits (262), Expect = 2e-23
Identities = 114/409 (27%), Positives = 162/409 (39%), Gaps = 49/409 (11%)
Query: 73 AAGYCADVDECA--ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC--EEQR 128
AAG DVDECA D C N+ S++C C+ GY+ + C D+DEC E
Sbjct: 39 AAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNELNG 96
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSELYAVLCP 186
C + C N PG++RC C GF L++DG CL + L CQ Y C
Sbjct: 97 GCVHD-CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCK 155
Query: 187 EG-PSKDNGGADIN------ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
EG DN I+ C C H E C C PG+ L ++
Sbjct: 156 EGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFE-----LAKNQ 210
Query: 240 DECDMHQSYCAGG---QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE-TE---THY 292
+C + ++ GG C +TA C C + + + C + ++ E TE T
Sbjct: 211 RDCILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSV 270
Query: 293 IESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD----- 347
++ D +R T CD C +T G C C +G+ L + C D
Sbjct: 271 VDGD-KRVKRRLLMETCAVNNGGCDR-TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQ 328
Query: 348 NRRGSC---WRRVV---DGQCEAAAPELLLRQECC-----CSVGLAWG-SXXXXXXXXXX 395
R G C + +V D C+ +LL ++ C CS+ S
Sbjct: 329 TRNGGCDHFCKNIVGSFDCGCKKGF-KLLTDEKSCQDVDECSLDRTCDHSCINHPGTFAC 387
Query: 396 XXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+G+ C D +EC+++ C CVNT GSY C C PG L
Sbjct: 388 ACNRGYTLYGFTHCGDTNECSINNGGCQ-QVCVNTVGSYECQCHPGYKL 435
Score = 109 bits (262), Expect = 2e-23
Identities = 57/162 (35%), Positives = 77/162 (47%), Gaps = 5/162 (3%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G C CK+ G C C G+ +G C+D+DEC+ C C+N GS+
Sbjct: 289 NNGGCDR-TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDH-FCKNIVGSFD 346
Query: 63 CLCEPGF-APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C+ GF T C DVDEC+ D C C+N G+F C C GY C D
Sbjct: 347 CGCKKGFKLLTDEKSCQDVDECSLDRTCDHS-CINHPGTFACACNRGYTLYGFT-HCGDT 404
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
+EC C NT GS+ C+C PG+ L + + C+ +K
Sbjct: 405 NECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVK 446
Score = 89.0 bits (211), Expect = 3e-17
Identities = 43/120 (35%), Positives = 64/120 (53%), Gaps = 3/120 (2%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
T G C + CKNI G F+C CK G++ ++ C+DVDEC R C C N G++
Sbjct: 329 TRNGGCDH-FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDEC-SLDRTCDHS-CINHPGTF 385
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C G+ +C D +EC+ ++ CVN+ GS++C C GY+ + CV+V
Sbjct: 386 ACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEV 445
Score = 60.9 bits (141), Expect = 9e-09
Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 3/107 (2%)
Query: 180 LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR 237
L A P G + G D++EC C + C+N Y+C C PGY + C
Sbjct: 27 LLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ-CE 85
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
DIDEC + C N G++ C C +G + C D+DEC
Sbjct: 86 DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDEC 132
Score = 37.5 bits (83), Expect = 0.097
Identities = 16/44 (36%), Positives = 20/44 (45%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+G C D+DEC C+N G+YRC C G L G
Sbjct: 80 EGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDG 123
>AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein.
Length = 999
Score = 133 bits (321), Expect = 1e-30
Identities = 101/366 (27%), Positives = 148/366 (40%), Gaps = 37/366 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C + C NI G + C C G+ +G C DVDEC +N C+ C N GSY
Sbjct: 95 NGG-CVHD-CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYE 151
Query: 63 CLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVN-----SEGSFQCVCEAGYRPTATRG 116
C C+ GF + + C E M K C + GS C C G+ +
Sbjct: 152 CCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQR 211
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
C+ C C +T C C P + + DGR+CL + +
Sbjct: 212 DCILT--CNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCL--------EREDTVLE 261
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-L 235
+E +G + + C G C +C++ G C C G+ DG
Sbjct: 262 VTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDR-TCKDTSTGVHCSCPVGFTLQLDGKT 320
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIES 295
C+DIDEC C C+N GSF C C +G + + + C+D+DEC + +
Sbjct: 321 CKDIDECQTRNGGC-DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCI 379
Query: 296 DY--------ERGDIPPTFPTRTELASPC--DNGR----CINTHGGFECECELGYVLDAT 341
++ RG F T + C +NG C+NT G +EC+C GY L
Sbjct: 380 NHPGTFACACNRGYTLYGF-THCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWN 438
Query: 342 AQRCLD 347
+ C++
Sbjct: 439 KKDCVE 444
Score = 118 bits (283), Expect = 6e-26
Identities = 108/397 (27%), Positives = 156/397 (39%), Gaps = 48/397 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
+ +C+N ++C CKPGY+ EG C D+DEC + C N G+Y C C G
Sbjct: 59 DALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDG 116
Query: 69 FAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
F G+ C DVDEC ++ CVN GS++C C+ G+ + + C + EE
Sbjct: 117 FMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC--IHRSEEG 174
Query: 128 RVCRNGR------CHNTP-GSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQACPAQGSE 179
C N C P GS CEC PGF L+ + R C L G G +C
Sbjct: 175 LSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTADG 234
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
P+ +G + + V E E + D L +
Sbjct: 235 PECSCHPQYKMHTDGRSCLEREDTV--------LEVTESNTTSVVDGDKRVKRRLL---M 283
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE--THY---IE 294
+ C ++ C C++T+ C CP G + + + C+DIDEC+ H+ I
Sbjct: 284 ETCAVNNGGC-DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIV 342
Query: 295 SDYERGDIPPTFPTRTE-----------LASPCDNGRCINTHGGFECECELGYVLDATAQ 343
++ G F T+ L CD+ CIN G F C C GY L
Sbjct: 343 GSFDCG-CKKGFKLLTDEKSCQDVDECSLDRTCDHS-CINHPGTFACACNRGYTLYGFT- 399
Query: 344 RCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C D S + +G C+ + EC C G
Sbjct: 400 HCGDTNECS----INNGGCQQVCVNTVGSYECQCHPG 432
Score = 109 bits (262), Expect = 2e-23
Identities = 114/409 (27%), Positives = 162/409 (39%), Gaps = 49/409 (11%)
Query: 73 AAGYCADVDECA--ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC--EEQR 128
AAG DVDECA D C N+ S++C C+ GY+ + C D+DEC E
Sbjct: 39 AAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNELNG 96
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQACPAQGSELYAVLCP 186
C + C N PG++RC C GF L++DG CL + L CQ Y C
Sbjct: 97 GCVHD-CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCK 155
Query: 187 EG-PSKDNGGADIN------ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
EG DN I+ C C H E C C PG+ L ++
Sbjct: 156 EGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFE-----LAKNQ 210
Query: 240 DECDMHQSYCAGG---QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE-TE---THY 292
+C + ++ GG C +TA C C + + + C + ++ E TE T
Sbjct: 211 RDCILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSV 270
Query: 293 IESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLD----- 347
++ D +R T CD C +T G C C +G+ L + C D
Sbjct: 271 VDGD-KRVKRRLLMETCAVNNGGCDR-TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQ 328
Query: 348 NRRGSC---WRRVV---DGQCEAAAPELLLRQECC-----CSVGLAWG-SXXXXXXXXXX 395
R G C + +V D C+ +LL ++ C CS+ S
Sbjct: 329 TRNGGCDHFCKNIVGSFDCGCKKGF-KLLTDEKSCQDVDECSLDRTCDHSCINHPGTFAC 387
Query: 396 XXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
+G+ C D +EC+++ C CVNT GSY C C PG L
Sbjct: 388 ACNRGYTLYGFTHCGDTNECSINNGGCQ-QVCVNTVGSYECQCHPGYKL 435
Score = 109 bits (262), Expect = 2e-23
Identities = 57/162 (35%), Positives = 77/162 (47%), Gaps = 5/162 (3%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G C CK+ G C C G+ +G C+D+DEC+ C C+N GS+
Sbjct: 289 NNGGCDR-TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDH-FCKNIVGSFD 346
Query: 63 CLCEPGF-APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C+ GF T C DVDEC+ D C C+N G+F C C GY C D
Sbjct: 347 CGCKKGFKLLTDEKSCQDVDECSLDRTCDHS-CINHPGTFACACNRGYTLYGFT-HCGDT 404
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK 163
+EC C NT GS+ C+C PG+ L + + C+ +K
Sbjct: 405 NECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVK 446
Score = 92.3 bits (219), Expect = 3e-18
Identities = 63/194 (32%), Positives = 91/194 (46%), Gaps = 18/194 (9%)
Query: 2 TNGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
T G C + CKNI G F+C CK G++ ++ C+DVDEC R C C N G++
Sbjct: 329 TRNGGCDH-FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDEC-SLDRTCDHS-CINHPGTF 385
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C G+ +C D +EC+ ++ CVN+ GS++C C GY+ + CV+V
Sbjct: 386 ACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEV 445
Query: 122 DECEEQRVCR--NGRCHNTPGSFRC--ECLPGFTLSNDG---RTCLGLKLGWGVSCQACP 174
V + C + G C C G LS+D RT + KL G C
Sbjct: 446 KGLLPTSVSPRVSLHCGKSGGGDGCFLRCHSGIHLSSDVTTIRTSVTFKLNEG----KCS 501
Query: 175 AQGSELYAVLCPEG 188
+ +EL+ PEG
Sbjct: 502 LKNAELF----PEG 511
Score = 60.9 bits (141), Expect = 9e-09
Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 3/107 (2%)
Query: 180 LYAVLCPEGPSKDNGGA-DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR 237
L A P G + G D++EC C + C+N Y+C C PGY + C
Sbjct: 27 LLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ-CE 85
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
DIDEC + C N G++ C C +G + C D+DEC
Sbjct: 86 DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDEC 132
Score = 37.5 bits (83), Expect = 0.097
Identities = 16/44 (36%), Positives = 20/44 (45%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
+G C D+DEC C+N G+YRC C G L G
Sbjct: 80 EGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDG 123
>AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 isoform b
variant protein.
Length = 418
Score = 132 bits (320), Expect = 2e-30
Identities = 74/206 (35%), Positives = 100/206 (48%), Gaps = 11/206 (5%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVD 81
C GYE SE +C+D+DEC CR + C N GS+ C C PG+ C D+D
Sbjct: 84 CAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE-QCVDID 141
Query: 82 ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
EC C RCVN+ GSF C C G++ A CVD++EC+ C +C+N GS
Sbjct: 142 ECTIPPYCH-QRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ-QCYNILGS 199
Query: 142 FRCECLPGFTLSNDGRTCLGLKLGWGVS--CQ-ACPAQGSELYAVLCPEGPS--KDNGGA 196
F C+C G+ LS+D C + S CQ C Q + ++ +CP+G +
Sbjct: 200 FICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNQPGK-FSCMCPQGYQVVRSRTCQ 258
Query: 197 DINECTAVPGACPHGSCENLEPGYRC 222
DINEC C N G+RC
Sbjct: 259 DINECETTNECREDEMCWNYHGGFRC 284
Score = 124 bits (299), Expect = 6e-28
Identities = 62/150 (41%), Positives = 78/150 (52%), Gaps = 7/150 (4%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+C N+ G F C C PGY+ G C D+DEC P C + RC NT GS+ C C PGF
Sbjct: 114 VCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQ 169
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
A Y C D++EC A + C +C N GSF C C GY ++ R C D+DEC
Sbjct: 170 LAANNYTCVDINECDASNQC-AQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSY 228
Query: 130 CRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
+C N PG F C C G+ + RTC
Sbjct: 229 LCQYQCVNQPGKFSCMCPQGYQVVR-SRTC 257
Score = 118 bits (285), Expect = 3e-26
Identities = 71/215 (33%), Positives = 97/215 (45%), Gaps = 20/215 (9%)
Query: 60 SYTCLCEPGFAPTAAGYCADVDECAADSM-CKGGR-CVNSEGSFQCVCEAGYRPTATRGA 117
S+ C G+ + C D+DEC A + C+ + C+N GSF C C GY+ +
Sbjct: 79 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ-- 136
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
CVD+DEC C RC NTPGSF C+C PGF L+ + TC+ + C A
Sbjct: 137 CVDIDECTIPPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDIN-----ECDASNQCA 190
Query: 178 SELYAVL------CPEG--PSKDN-GGADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
+ Y +L C +G S D DI+EC C + C N + C+C GY
Sbjct: 191 QQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNQPGKFSCMCPQGY 249
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
C+DI+EC+ C N G F C
Sbjct: 250 QVVRSRTCQDINECETTNECREDEMCWNYHGGFRC 284
Score = 97.5 bits (232), Expect = 9e-20
Identities = 69/202 (34%), Positives = 90/202 (44%), Gaps = 14/202 (6%)
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGFTL 152
+ S S + C AGY + C D+DEC CR + C N GSF C+C PG+
Sbjct: 74 IPSNPSHRIQCAAGYEQSE-HNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGY-- 130
Query: 153 SNDGRTCLGL-KLGWGVSC-QACPAQGSELYAVLCPEGPSKDNGGA--DINECTAVPGAC 208
G C+ + + C Q C Y P N DINEC A C
Sbjct: 131 QKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDA-SNQC 189
Query: 209 PHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
C N+ + C C+ GY +D L C DIDEC SY QC N G F+C+CP+
Sbjct: 190 AQ-QCYNILGSFICQCNQGYELSSDRLNCEDIDECRT-SSYLCQYQCVNQPGKFSCMCPQ 247
Query: 268 GTRHEPELQLCRDIDECEGETE 289
G + + C+DI+ECE E
Sbjct: 248 GYQ-VVRSRTCQDINECETTNE 268
Score = 83.8 bits (198), Expect = 1e-15
Identities = 71/225 (31%), Positives = 84/225 (37%), Gaps = 55/225 (24%)
Query: 218 PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQ 276
P +R C GY +C+DIDEC C Q C N GSF C CP G + E
Sbjct: 78 PSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ- 136
Query: 277 LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGY 336
C DIDEC IPP C RC+NT G F C+C G+
Sbjct: 137 -CVDIDECT----------------IPPY----------CHQ-RCVNTPGSFYCQCSPGF 168
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
L A C+D C QC +L C C+ G S
Sbjct: 169 QLAANNYTCVD--INEC---DASNQCAQQCYNILGSFICQCNQGYELSS----------- 212
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
D C D+DEC S+ LC CVN G + C CP G
Sbjct: 213 --------DRLNCEDIDECRTSSYLCQ-YQCVNQPGKFSCMCPQG 248
Score = 80.2 bits (189), Expect = 1e-14
Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G F C C GYE S+ C D+DECR + +C+ +C N G ++C+C G+
Sbjct: 193 CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNQPGKFSCMCPQGYQV 251
Query: 72 TAAGYCADVDECAADSMCKGGR-CVNSEGSFQC 103
+ C D++EC + C+ C N G F+C
Sbjct: 252 VRSRTCQDINECETTNECREDEMCWNYHGGFRC 284
Score = 39.1 bits (87), Expect = 0.032
Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
G C D+DEC + C CVNT GS+ C C PG L
Sbjct: 134 GEQCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQL 170
Score = 33.1 bits (72), Expect = 2.1
Identities = 34/126 (26%), Positives = 45/126 (35%), Gaps = 28/126 (22%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
CIN G F C+C GY ++C+D C + C C CS G
Sbjct: 115 CINLRGSFACQCPPGY--QKRGEQCVDI--DEC---TIPPYCHQRCVNTPGSFYCQCSPG 167
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPP 440
+ + TC D++EC S + CA C N GS+ C C
Sbjct: 168 FQLAA-------------------NNYTCVDINECDASNQ-CAQ-QCYNILGSFICQCNQ 206
Query: 441 GLTLDS 446
G L S
Sbjct: 207 GYELSS 212
>U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein
protein.
Length = 387
Score = 132 bits (319), Expect = 2e-30
Identities = 72/205 (35%), Positives = 97/205 (47%), Gaps = 9/205 (4%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVD 81
C GYE SE +C+D+DEC CR + C N GS+ C C PG+ C D+D
Sbjct: 53 CAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE-QCVDID 110
Query: 82 ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
EC C RCVN+ GSF C C G++ A CVD++EC+ C +C+N GS
Sbjct: 111 ECTIPPYCH-QRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ-QCYNILGS 168
Query: 142 FRCECLPGFTLSNDGRTCLGLKLGWGVS--CQACPAQGSELYAVLCPEGPS--KDNGGAD 197
F C+C G+ LS+D C + S CQ ++ +CP+G + D
Sbjct: 169 FICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQD 228
Query: 198 INECTAVPGACPHGSCENLEPGYRC 222
INEC C N G+RC
Sbjct: 229 INECETTNECREDEMCWNYHGGFRC 253
Score = 124 bits (299), Expect = 6e-28
Identities = 62/150 (41%), Positives = 78/150 (52%), Gaps = 7/150 (4%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+C N+ G F C C PGY+ G C D+DEC P C + RC NT GS+ C C PGF
Sbjct: 83 VCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQ 138
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
A Y C D++EC A + C +C N GSF C C GY ++ R C D+DEC
Sbjct: 139 LAANNYTCVDINECDASNQC-AQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSY 197
Query: 130 CRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
+C N PG F C C G+ + RTC
Sbjct: 198 LCQYQCVNEPGKFSCMCPQGYQVVR-SRTC 226
Score = 120 bits (288), Expect = 1e-26
Identities = 74/216 (34%), Positives = 100/216 (46%), Gaps = 22/216 (10%)
Query: 60 SYTCLCEPGFAPTAAGYCADVDECAADSM-CKGGR-CVNSEGSFQCVCEAGYRPTATRGA 117
S+ C G+ + C D+DEC A + C+ + C+N GSF C C GY+ +
Sbjct: 48 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ-- 105
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
CVD+DEC C RC NTPGSF C+C PGF L+ + TC+ + C A
Sbjct: 106 CVDIDECTIPPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDIN-----ECDASNQCA 159
Query: 178 SELYAVL------CPEG--PSKDN-GGADINECTAVPGACPHGSCENLEPG-YRCICDPG 227
+ Y +L C +G S D DI+EC C + C N EPG + C+C G
Sbjct: 160 QQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVN-EPGKFSCMCPQG 217
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
Y C+DI+EC+ C N G F C
Sbjct: 218 YQVVRSRTCQDINECETTNECREDEMCWNYHGGFRC 253
Score = 97.5 bits (232), Expect = 9e-20
Identities = 69/202 (34%), Positives = 90/202 (44%), Gaps = 14/202 (6%)
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGFTL 152
+ S S + C AGY + C D+DEC CR + C N GSF C+C PG+
Sbjct: 43 IPSNPSHRIQCAAGYEQSE-HNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGY-- 99
Query: 153 SNDGRTCLGL-KLGWGVSC-QACPAQGSELYAVLCPEGPSKDNGGA--DINECTAVPGAC 208
G C+ + + C Q C Y P N DINEC A C
Sbjct: 100 QKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDA-SNQC 158
Query: 209 PHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
C N+ + C C+ GY +D L C DIDEC SY QC N G F+C+CP+
Sbjct: 159 AQ-QCYNILGSFICQCNQGYELSSDRLNCEDIDECRT-SSYLCQYQCVNEPGKFSCMCPQ 216
Query: 268 GTRHEPELQLCRDIDECEGETE 289
G + + C+DI+ECE E
Sbjct: 217 GYQ-VVRSRTCQDINECETTNE 237
Score = 83.8 bits (198), Expect = 1e-15
Identities = 71/225 (31%), Positives = 84/225 (37%), Gaps = 55/225 (24%)
Query: 218 PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQ 276
P +R C GY +C+DIDEC C Q C N GSF C CP G + E
Sbjct: 47 PSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ- 105
Query: 277 LCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGY 336
C DIDEC IPP C RC+NT G F C+C G+
Sbjct: 106 -CVDIDECT----------------IPPY----------CHQ-RCVNTPGSFYCQCSPGF 137
Query: 337 VLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
L A C+D C QC +L C C+ G S
Sbjct: 138 QLAANNYTCVD--INEC---DASNQCAQQCYNILGSFICQCNQGYELSS----------- 181
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
D C D+DEC S+ LC CVN G + C CP G
Sbjct: 182 --------DRLNCEDIDECRTSSYLCQ-YQCVNEPGKFSCMCPQG 217
Score = 80.2 bits (189), Expect = 1e-14
Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G F C C GYE S+ C D+DECR + +C+ +C N G ++C+C G+
Sbjct: 162 CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQV 220
Query: 72 TAAGYCADVDECAADSMCKGGR-CVNSEGSFQC 103
+ C D++EC + C+ C N G F+C
Sbjct: 221 VRSRTCQDINECETTNECREDEMCWNYHGGFRC 253
Score = 39.1 bits (87), Expect = 0.032
Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
G C D+DEC + C CVNT GS+ C C PG L
Sbjct: 103 GEQCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQL 139
Score = 33.1 bits (72), Expect = 2.1
Identities = 34/126 (26%), Positives = 45/126 (35%), Gaps = 28/126 (22%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
CIN G F C+C GY ++C+D C + C C CS G
Sbjct: 84 CINLRGSFACQCPPGY--QKRGEQCVDI--DEC---TIPPYCHQRCVNTPGSFYCQCSPG 136
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPP 440
+ + TC D++EC S + CA C N GS+ C C
Sbjct: 137 FQLAA-------------------NNYTCVDINECDASNQ-CAQ-QCYNILGSFICQCNQ 175
Query: 441 GLTLDS 446
G L S
Sbjct: 176 GYELSS 181
>BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 132 bits (319), Expect = 2e-30
Identities = 72/205 (35%), Positives = 97/205 (47%), Gaps = 9/205 (4%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVD 81
C GYE SE +C+D+DEC CR + C N GS+ C C PG+ C D+D
Sbjct: 159 CAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE-QCVDID 216
Query: 82 ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
EC C RCVN+ GSF C C G++ A CVD++EC+ C +C+N GS
Sbjct: 217 ECTIPPYCH-QRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ-QCYNILGS 274
Query: 142 FRCECLPGFTLSNDGRTCLGLKLGWGVS--CQACPAQGSELYAVLCPEGPS--KDNGGAD 197
F C+C G+ LS+D C + S CQ ++ +CP+G + D
Sbjct: 275 FICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQD 334
Query: 198 INECTAVPGACPHGSCENLEPGYRC 222
INEC C N G+RC
Sbjct: 335 INECETTNECREDEMCWNYHGGFRC 359
Score = 124 bits (299), Expect = 6e-28
Identities = 62/150 (41%), Positives = 78/150 (52%), Gaps = 7/150 (4%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+C N+ G F C C PGY+ G C D+DEC P C + RC NT GS+ C C PGF
Sbjct: 189 VCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQ 244
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
A Y C D++EC A + C +C N GSF C C GY ++ R C D+DEC
Sbjct: 245 LAANNYTCVDINECDASNQC-AQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSY 303
Query: 130 CRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
+C N PG F C C G+ + RTC
Sbjct: 304 LCQYQCVNEPGKFSCMCPQGYQVVR-SRTC 332
Score = 120 bits (288), Expect = 1e-26
Identities = 74/216 (34%), Positives = 100/216 (46%), Gaps = 22/216 (10%)
Query: 60 SYTCLCEPGFAPTAAGYCADVDECAADSM-CKGGR-CVNSEGSFQCVCEAGYRPTATRGA 117
S+ C G+ + C D+DEC A + C+ + C+N GSF C C GY+ +
Sbjct: 154 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ-- 211
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
CVD+DEC C RC NTPGSF C+C PGF L+ + TC+ + C A
Sbjct: 212 CVDIDECTIPPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDIN-----ECDASNQCA 265
Query: 178 SELYAVL------CPEG--PSKDN-GGADINECTAVPGACPHGSCENLEPG-YRCICDPG 227
+ Y +L C +G S D DI+EC C + C N EPG + C+C G
Sbjct: 266 QQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVN-EPGKFSCMCPQG 323
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
Y C+DI+EC+ C N G F C
Sbjct: 324 YQVVRSRTCQDINECETTNECREDEMCWNYHGGFRC 359
Score = 97.5 bits (232), Expect = 9e-20
Identities = 69/202 (34%), Positives = 90/202 (44%), Gaps = 14/202 (6%)
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGFTL 152
+ S S + C AGY + C D+DEC CR + C N GSF C+C PG+
Sbjct: 149 IPSNPSHRIQCAAGYEQSE-HNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGY-- 205
Query: 153 SNDGRTCLGL-KLGWGVSC-QACPAQGSELYAVLCPEGPSKDNGGA--DINECTAVPGAC 208
G C+ + + C Q C Y P N DINEC A C
Sbjct: 206 QKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDA-SNQC 264
Query: 209 PHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
C N+ + C C+ GY +D L C DIDEC SY QC N G F+C+CP+
Sbjct: 265 AQ-QCYNILGSFICQCNQGYELSSDRLNCEDIDECRT-SSYLCQYQCVNEPGKFSCMCPQ 322
Query: 268 GTRHEPELQLCRDIDECEGETE 289
G + + C+DI+ECE E
Sbjct: 323 GYQ-VVRSRTCQDINECETTNE 343
Score = 92.3 bits (219), Expect = 3e-18
Identities = 108/367 (29%), Positives = 143/367 (38%), Gaps = 60/367 (16%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLCEPG------------F 69
C GYE C+D+DEC P C+ G +C N G Y CL +
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET 88
Query: 70 APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRP---TATRGACVDVDECEE 126
P A AA SM G V G F A P T + + +
Sbjct: 89 QPAEGTSGATTGVVAASSMATSG--VLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADP 146
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGV-SC---QAC-PAQGSEL 180
QR+ N S R +C G+ S + C + + G +C Q C +GS
Sbjct: 147 QRIPSN-------PSHRIQCAAGYEQS-EHNVCQDIDECTAGTHNCRADQVCINLRGS-- 196
Query: 181 YAVLCPEGPSK-DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRD 238
+A CP G K DI+ECT +P C H C N + C C PG+ A+ C D
Sbjct: 197 FACQCPPGYQKRGEQCVDIDECT-IPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVD 254
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
I+ECD + CA QC N GSF C C +G + C DIDEC + + E
Sbjct: 255 INECDA-SNQCA-QQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNE 312
Query: 299 RGDIPPTFP-------TRT-------ELASPC-DNGRCINTHGGFEC----ECELGYVLD 339
G P +RT E + C ++ C N HGGF C C+ Y+L
Sbjct: 313 PGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYIL- 371
Query: 340 ATAQRCL 346
RC+
Sbjct: 372 TPENRCV 378
Score = 87.4 bits (207), Expect = 9e-17
Identities = 96/355 (27%), Positives = 123/355 (34%), Gaps = 78/355 (21%)
Query: 105 CEAGYRPTATRGACVDVDECE-EQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGR----- 157
C GY R C D+DEC+ C+ G +C N G + C + N+ +
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET 88
Query: 158 --------TCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGAD--INECTAVPGA 207
G+ ++ G + + GP G + I A P
Sbjct: 89 QPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQR 148
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCP 266
P P +R C GY +C+DIDEC C Q C N GSF C CP
Sbjct: 149 IPSN------PSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCP 202
Query: 267 EGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG 326
G + E C DIDEC IPP C RC+NT G
Sbjct: 203 PGYQKRGEQ--CVDIDECT----------------IPPY----------CHQ-RCVNTPG 233
Query: 327 GFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSX 386
F C+C G+ L A C+D C QC +L C C+ G S
Sbjct: 234 SFYCQCSPGFQLAANNYTCVD--INEC---DASNQCAQQCYNILGSFICQCNQGYELSS- 287
Query: 387 XXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
D C D+DEC S+ LC CVN G + C CP G
Sbjct: 288 ------------------DRLNCEDIDECRTSSYLCQ-YQCVNEPGKFSCMCPQG 323
Score = 80.2 bits (189), Expect = 1e-14
Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G F C C GYE S+ C D+DECR + +C+ +C N G ++C+C G+
Sbjct: 268 CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQV 326
Query: 72 TAAGYCADVDECAADSMCKGGR-CVNSEGSFQC 103
+ C D++EC + C+ C N G F+C
Sbjct: 327 VRSRTCQDINECETTNECREDEMCWNYHGGFRC 359
Score = 39.1 bits (87), Expect = 0.032
Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
G C D+DEC + C CVNT GS+ C C PG L
Sbjct: 209 GEQCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQL 245
Score = 33.1 bits (72), Expect = 2.1
Identities = 34/126 (26%), Positives = 45/126 (35%), Gaps = 28/126 (22%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
CIN G F C+C GY ++C+D C + C C CS G
Sbjct: 190 CINLRGSFACQCPPGY--QKRGEQCVDI--DEC---TIPPYCHQRCVNTPGSFYCQCSPG 242
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPP 440
+ + TC D++EC S + CA C N GS+ C C
Sbjct: 243 FQLAA-------------------NNYTCVDINECDASNQ-CAQ-QCYNILGSFICQCNQ 281
Query: 441 GLTLDS 446
G L S
Sbjct: 282 GYELSS 287
>BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 132 bits (319), Expect = 2e-30
Identities = 72/205 (35%), Positives = 97/205 (47%), Gaps = 9/205 (4%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVD 81
C GYE SE +C+D+DEC CR + C N GS+ C C PG+ C D+D
Sbjct: 159 CAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE-QCVDID 216
Query: 82 ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
EC C RCVN+ GSF C C G++ A CVD++EC+ C +C+N GS
Sbjct: 217 ECTIPPYCH-QRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ-QCYNILGS 274
Query: 142 FRCECLPGFTLSNDGRTCLGLKLGWGVS--CQACPAQGSELYAVLCPEGPS--KDNGGAD 197
F C+C G+ LS+D C + S CQ ++ +CP+G + D
Sbjct: 275 FICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQD 334
Query: 198 INECTAVPGACPHGSCENLEPGYRC 222
INEC C N G+RC
Sbjct: 335 INECETTNECREDEMCWNYHGGFRC 359
Score = 124 bits (299), Expect = 6e-28
Identities = 62/150 (41%), Positives = 78/150 (52%), Gaps = 7/150 (4%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+C N+ G F C C PGY+ G C D+DEC P C + RC NT GS+ C C PGF
Sbjct: 189 VCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQ 244
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
A Y C D++EC A + C +C N GSF C C GY ++ R C D+DEC
Sbjct: 245 LAANNYTCVDINECDASNQC-AQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSY 303
Query: 130 CRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
+C N PG F C C G+ + RTC
Sbjct: 304 LCQYQCVNEPGKFSCMCPQGYQVVR-SRTC 332
Score = 120 bits (288), Expect = 1e-26
Identities = 74/216 (34%), Positives = 100/216 (46%), Gaps = 22/216 (10%)
Query: 60 SYTCLCEPGFAPTAAGYCADVDECAADSM-CKGGR-CVNSEGSFQCVCEAGYRPTATRGA 117
S+ C G+ + C D+DEC A + C+ + C+N GSF C C GY+ +
Sbjct: 154 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ-- 211
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
CVD+DEC C RC NTPGSF C+C PGF L+ + TC+ + C A
Sbjct: 212 CVDIDECTIPPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDIN-----ECDASNQCA 265
Query: 178 SELYAVL------CPEG--PSKDN-GGADINECTAVPGACPHGSCENLEPG-YRCICDPG 227
+ Y +L C +G S D DI+EC C + C N EPG + C+C G
Sbjct: 266 QQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVN-EPGKFSCMCPQG 323
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
Y C+DI+EC+ C N G F C
Sbjct: 324 YQVVRSRTCQDINECETTNECREDEMCWNYHGGFRC 359
Score = 97.5 bits (232), Expect = 9e-20
Identities = 69/202 (34%), Positives = 90/202 (44%), Gaps = 14/202 (6%)
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGFTL 152
+ S S + C AGY + C D+DEC CR + C N GSF C+C PG+
Sbjct: 149 IPSNPSHRIQCAAGYEQSE-HNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGY-- 205
Query: 153 SNDGRTCLGL-KLGWGVSC-QACPAQGSELYAVLCPEGPSKDNGGA--DINECTAVPGAC 208
G C+ + + C Q C Y P N DINEC A C
Sbjct: 206 QKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDA-SNQC 264
Query: 209 PHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
C N+ + C C+ GY +D L C DIDEC SY QC N G F+C+CP+
Sbjct: 265 AQ-QCYNILGSFICQCNQGYELSSDRLNCEDIDECRT-SSYLCQYQCVNEPGKFSCMCPQ 322
Query: 268 GTRHEPELQLCRDIDECEGETE 289
G + + C+DI+ECE E
Sbjct: 323 GYQ-VVRSRTCQDINECETTNE 343
Score = 92.3 bits (219), Expect = 3e-18
Identities = 108/367 (29%), Positives = 143/367 (38%), Gaps = 60/367 (16%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLCEPG------------F 69
C GYE C+D+DEC P C+ G +C N G Y CL +
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET 88
Query: 70 APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRP---TATRGACVDVDECEE 126
P A AA SM G V G F A P T + + +
Sbjct: 89 QPAEGTSGATTGVVAASSMATSG--VLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADP 146
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGV-SC---QAC-PAQGSEL 180
QR+ N S R +C G+ S + C + + G +C Q C +GS
Sbjct: 147 QRIPSN-------PSHRIQCAAGYEQS-EHNVCQDIDECTAGTHNCRADQVCINLRGS-- 196
Query: 181 YAVLCPEGPSK-DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRD 238
+A CP G K DI+ECT +P C H C N + C C PG+ A+ C D
Sbjct: 197 FACQCPPGYQKRGEQCVDIDECT-IPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVD 254
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
I+ECD + CA QC N GSF C C +G + C DIDEC + + E
Sbjct: 255 INECDA-SNQCA-QQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNE 312
Query: 299 RGDIPPTFP-------TRT-------ELASPC-DNGRCINTHGGFEC----ECELGYVLD 339
G P +RT E + C ++ C N HGGF C C+ Y+L
Sbjct: 313 PGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYIL- 371
Query: 340 ATAQRCL 346
RC+
Sbjct: 372 TPENRCV 378
Score = 87.4 bits (207), Expect = 9e-17
Identities = 96/355 (27%), Positives = 123/355 (34%), Gaps = 78/355 (21%)
Query: 105 CEAGYRPTATRGACVDVDECE-EQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGR----- 157
C GY R C D+DEC+ C+ G +C N G + C + N+ +
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET 88
Query: 158 --------TCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGAD--INECTAVPGA 207
G+ ++ G + + GP G + I A P
Sbjct: 89 QPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQR 148
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCP 266
P P +R C GY +C+DIDEC C Q C N GSF C CP
Sbjct: 149 IPSN------PSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCP 202
Query: 267 EGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG 326
G + E C DIDEC IPP C RC+NT G
Sbjct: 203 PGYQKRGEQ--CVDIDECT----------------IPPY----------CHQ-RCVNTPG 233
Query: 327 GFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSX 386
F C+C G+ L A C+D C QC +L C C+ G S
Sbjct: 234 SFYCQCSPGFQLAANNYTCVD--INEC---DASNQCAQQCYNILGSFICQCNQGYELSS- 287
Query: 387 XXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
D C D+DEC S+ LC CVN G + C CP G
Sbjct: 288 ------------------DRLNCEDIDECRTSSYLCQ-YQCVNEPGKFSCMCPQG 323
Score = 80.2 bits (189), Expect = 1e-14
Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G F C C GYE S+ C D+DECR + +C+ +C N G ++C+C G+
Sbjct: 268 CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQV 326
Query: 72 TAAGYCADVDECAADSMCKGGR-CVNSEGSFQC 103
+ C D++EC + C+ C N G F+C
Sbjct: 327 VRSRTCQDINECETTNECREDEMCWNYHGGFRC 359
Score = 39.1 bits (87), Expect = 0.032
Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
G C D+DEC + C CVNT GS+ C C PG L
Sbjct: 209 GEQCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQL 245
Score = 33.1 bits (72), Expect = 2.1
Identities = 34/126 (26%), Positives = 45/126 (35%), Gaps = 28/126 (22%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
CIN G F C+C GY ++C+D C + C C CS G
Sbjct: 190 CINLRGSFACQCPPGY--QKRGEQCVDI--DEC---TIPPYCHQRCVNTPGSFYCQCSPG 242
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPP 440
+ + TC D++EC S + CA C N GS+ C C
Sbjct: 243 FQLAA-------------------NNYTCVDINECDASNQ-CAQ-QCYNILGSFICQCNQ 281
Query: 441 GLTLDS 446
G L S
Sbjct: 282 GYELSS 287
>AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 132 bits (319), Expect = 2e-30
Identities = 72/205 (35%), Positives = 97/205 (47%), Gaps = 9/205 (4%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVD 81
C GYE SE +C+D+DEC CR + C N GS+ C C PG+ C D+D
Sbjct: 159 CAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE-QCVDID 216
Query: 82 ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
EC C RCVN+ GSF C C G++ A CVD++EC+ C +C+N GS
Sbjct: 217 ECTIPPYCH-QRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ-QCYNILGS 274
Query: 142 FRCECLPGFTLSNDGRTCLGLKLGWGVS--CQACPAQGSELYAVLCPEGPS--KDNGGAD 197
F C+C G+ LS+D C + S CQ ++ +CP+G + D
Sbjct: 275 FICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQD 334
Query: 198 INECTAVPGACPHGSCENLEPGYRC 222
INEC C N G+RC
Sbjct: 335 INECETTNECREDEMCWNYHGGFRC 359
Score = 124 bits (299), Expect = 6e-28
Identities = 62/150 (41%), Positives = 78/150 (52%), Gaps = 7/150 (4%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+C N+ G F C C PGY+ G C D+DEC P C + RC NT GS+ C C PGF
Sbjct: 189 VCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQ 244
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
A Y C D++EC A + C +C N GSF C C GY ++ R C D+DEC
Sbjct: 245 LAANNYTCVDINECDASNQC-AQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSY 303
Query: 130 CRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
+C N PG F C C G+ + RTC
Sbjct: 304 LCQYQCVNEPGKFSCMCPQGYQVVR-SRTC 332
Score = 120 bits (288), Expect = 1e-26
Identities = 74/216 (34%), Positives = 100/216 (46%), Gaps = 22/216 (10%)
Query: 60 SYTCLCEPGFAPTAAGYCADVDECAADSM-CKGGR-CVNSEGSFQCVCEAGYRPTATRGA 117
S+ C G+ + C D+DEC A + C+ + C+N GSF C C GY+ +
Sbjct: 154 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ-- 211
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
CVD+DEC C RC NTPGSF C+C PGF L+ + TC+ + C A
Sbjct: 212 CVDIDECTIPPYCHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDIN-----ECDASNQCA 265
Query: 178 SELYAVL------CPEG--PSKDN-GGADINECTAVPGACPHGSCENLEPG-YRCICDPG 227
+ Y +L C +G S D DI+EC C + C N EPG + C+C G
Sbjct: 266 QQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVN-EPGKFSCMCPQG 323
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
Y C+DI+EC+ C N G F C
Sbjct: 324 YQVVRSRTCQDINECETTNECREDEMCWNYHGGFRC 359
Score = 97.5 bits (232), Expect = 9e-20
Identities = 69/202 (34%), Positives = 90/202 (44%), Gaps = 14/202 (6%)
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGFTL 152
+ S S + C AGY + C D+DEC CR + C N GSF C+C PG+
Sbjct: 149 IPSNPSHRIQCAAGYEQSE-HNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGY-- 205
Query: 153 SNDGRTCLGL-KLGWGVSC-QACPAQGSELYAVLCPEGPSKDNGGA--DINECTAVPGAC 208
G C+ + + C Q C Y P N DINEC A C
Sbjct: 206 QKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDA-SNQC 264
Query: 209 PHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
C N+ + C C+ GY +D L C DIDEC SY QC N G F+C+CP+
Sbjct: 265 AQ-QCYNILGSFICQCNQGYELSSDRLNCEDIDECRT-SSYLCQYQCVNEPGKFSCMCPQ 322
Query: 268 GTRHEPELQLCRDIDECEGETE 289
G + + C+DI+ECE E
Sbjct: 323 GYQ-VVRSRTCQDINECETTNE 343
Score = 92.3 bits (219), Expect = 3e-18
Identities = 108/367 (29%), Positives = 143/367 (38%), Gaps = 60/367 (16%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCLCEPG------------F 69
C GYE C+D+DEC P C+ G +C N G Y CL +
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET 88
Query: 70 APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRP---TATRGACVDVDECEE 126
P A AA SM G V G F A P T + + +
Sbjct: 89 QPAEGTSGATTGVVAASSMATSG--VLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADP 146
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGV-SC---QAC-PAQGSEL 180
QR+ N S R +C G+ S + C + + G +C Q C +GS
Sbjct: 147 QRIPSN-------PSHRIQCAAGYEQS-EHNVCQDIDECTAGTHNCRADQVCINLRGS-- 196
Query: 181 YAVLCPEGPSK-DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRD 238
+A CP G K DI+ECT +P C H C N + C C PG+ A+ C D
Sbjct: 197 FACQCPPGYQKRGEQCVDIDECT-IPPYC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVD 254
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
I+ECD + CA QC N GSF C C +G + C DIDEC + + E
Sbjct: 255 INECDA-SNQCA-QQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNE 312
Query: 299 RGDIPPTFP-------TRT-------ELASPC-DNGRCINTHGGFEC----ECELGYVLD 339
G P +RT E + C ++ C N HGGF C C+ Y+L
Sbjct: 313 PGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYIL- 371
Query: 340 ATAQRCL 346
RC+
Sbjct: 372 TPENRCV 378
Score = 87.4 bits (207), Expect = 9e-17
Identities = 96/355 (27%), Positives = 123/355 (34%), Gaps = 78/355 (21%)
Query: 105 CEAGYRPTATRGACVDVDECE-EQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGR----- 157
C GY R C D+DEC+ C+ G +C N G + C + N+ +
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET 88
Query: 158 --------TCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGAD--INECTAVPGA 207
G+ ++ G + + GP G + I A P
Sbjct: 89 QPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQR 148
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCP 266
P P +R C GY +C+DIDEC C Q C N GSF C CP
Sbjct: 149 IPSN------PSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCP 202
Query: 267 EGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG 326
G + E C DIDEC IPP C RC+NT G
Sbjct: 203 PGYQKRGEQ--CVDIDECT----------------IPPY----------CHQ-RCVNTPG 233
Query: 327 GFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSX 386
F C+C G+ L A C+D C QC +L C C+ G S
Sbjct: 234 SFYCQCSPGFQLAANNYTCVD--INEC---DASNQCAQQCYNILGSFICQCNQGYELSS- 287
Query: 387 XXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
D C D+DEC S+ LC CVN G + C CP G
Sbjct: 288 ------------------DRLNCEDIDECRTSSYLCQ-YQCVNEPGKFSCMCPQG 323
Score = 80.2 bits (189), Expect = 1e-14
Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G F C C GYE S+ C D+DECR + +C+ +C N G ++C+C G+
Sbjct: 268 CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQV 326
Query: 72 TAAGYCADVDECAADSMCKGGR-CVNSEGSFQC 103
+ C D++EC + C+ C N G F+C
Sbjct: 327 VRSRTCQDINECETTNECREDEMCWNYHGGFRC 359
Score = 39.1 bits (87), Expect = 0.032
Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
G C D+DEC + C CVNT GS+ C C PG L
Sbjct: 209 GEQCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQL 245
Score = 33.1 bits (72), Expect = 2.1
Identities = 34/126 (26%), Positives = 45/126 (35%), Gaps = 28/126 (22%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
CIN G F C+C GY ++C+D C + C C CS G
Sbjct: 190 CINLRGSFACQCPPGY--QKRGEQCVDI--DEC---TIPPYCHQRCVNTPGSFYCQCSPG 242
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPP 440
+ + TC D++EC S + CA C N GS+ C C
Sbjct: 243 FQLAA-------------------NNYTCVDINECDASNQ-CAQ-QCYNILGSFICQCNQ 281
Query: 441 GLTLDS 446
G L S
Sbjct: 282 GYELSS 287
>Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.
Length = 1223
Score = 130 bits (314), Expect = 1e-29
Identities = 130/461 (28%), Positives = 191/461 (41%), Gaps = 61/461 (13%)
Query: 7 CTNG-ICKNIDGG-FECICKPGYESGSEGALCRDVDE-CRDNPRVCRRGRCRNTAGSYTC 63
CTNG C N + + C C GY G C + C NP G C + C
Sbjct: 301 CTNGGTCINAEPDQYRCTCPDGYS----GRNCEKAEHACTSNP-CANGGSCHEVPSGFEC 355
Query: 64 LCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C G++ PT A AD+DECA++ GG CV+ F+C+C + + +D +
Sbjct: 356 HCPSGWSGPTCAS--ADIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQ---LDAN 410
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGSE 179
ECE + C N G + C+C+PG+ N + C G + G +C+ G
Sbjct: 411 ECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRG-QCQHGGTCKDL-VNG-- 466
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
Y +CP G + + +EC + P C G CE+L G+ C C G+ + LC
Sbjct: 467 -YQCVCPRGFGGRHCELERDECASSP--CHSGGLCEDLADGFHCHCPQGF---SGPLCEV 520
Query: 238 DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
D+D C+ S C G +C N G + C CP+ + + R + C G I D
Sbjct: 521 DVDLCE--PSPCRNGARCYNLEGDYYCACPDDFGGK-NCSVPR--EPCPGGA-CRVI--D 572
Query: 297 YERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGY--------VLDATAQRCL 346
D P P T + C +GRC++ GG F C C+ G+ + D Q C
Sbjct: 573 GCGSDAGPGMP-GTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCR 631
Query: 347 DNRRGSCWRRVVDGQCEAAA---PEL--LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
+ G+C V +C + EL +C + G G+
Sbjct: 632 NG--GTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 689
Query: 402 AKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
G TC E A C+ GGTC ++ ++RC CPPG
Sbjct: 690 ---KGKTCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPG 726
Score = 130 bits (313), Expect = 1e-29
Identities = 137/469 (29%), Positives = 185/469 (39%), Gaps = 72/469 (15%)
Query: 4 GGMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
G C N CKN+ GG+ C C PG++ G C +V++CR C+ G C++
Sbjct: 414 GKPCLNAFSCKNLIGGYYCDCIPGWK----GINCHINVNDCRGQ---CQHGGTCKDLVNG 466
Query: 61 YTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
Y C+C GF +C + DECA+ GG C + F C C G+ V
Sbjct: 467 YQCVCPRGFG---GRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---V 520
Query: 120 DVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
DVD CE CRNG RC+N G + C C F G+ C V + CP
Sbjct: 521 DVDLCEPSP-CRNGARCYNLEGDYYCACPDDF----GGKNC-------SVPREPCPGGAC 568
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPG--YRCICDPGYHPDADGL 235
+ +G D G TA G C PHG C + +PG + CICD G+
Sbjct: 569 RVI-----DGCGSDAGPG--MPGTAASGVCGPHGRCVS-QPGGNFSCICDSGF---TGTY 617
Query: 236 CRD-IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI--DECEGETETHY 292
C + ID+C + Q GG C + +F C CP G E D D C +
Sbjct: 618 CHENIDDC-LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYD 676
Query: 293 IESDY----ERGDIPPTFPTRTEL--ASPCDN-GRCINTHGGFECECELGYVLDATA--- 342
+ +D+ + G T +R A C N G C ++ F C C G+ A
Sbjct: 677 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 736
Query: 343 -QRCLDN---RRGSCWRRVVDGQC---EAAAPELLLRQECCCSVGLAW--GSXXXXXXXX 393
CL N G+C C + C+ + G
Sbjct: 737 NSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 796
Query: 394 XXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR ++DEC S+ G TCV+ YRC CPPG
Sbjct: 797 RCECAPGFA---GPDCRINIDECQ-SSPCAYGATCVDEINGYRCSCPPG 841
Score = 114 bits (275), Expect = 5e-25
Identities = 132/473 (27%), Positives = 178/473 (37%), Gaps = 67/473 (14%)
Query: 6 MCTNGICKNIDGGF----ECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
+C G C + GG EC C G++ G C DEC P C G C +
Sbjct: 228 VCKQG-CNLLHGGCTVPGECRCSYGWQ----GRFC---DECVPYPG-CVHGSC---VEPW 275
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMC-KGGRCVNSE-GSFQCVCEAGYRPTATRGACV 119
C CE + D++ C + C GG C+N+E ++C C GY + C
Sbjct: 276 QCNCETNWGGLLCD--KDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNCE 329
Query: 120 DVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+ C NG CH P F C C G++ G TC + S C A G+
Sbjct: 330 KAEHACTSNPCANGGSCHEVPSGFECHCPSGWS----GPTCASADIDECAS-NPCAAGGT 384
Query: 179 -----ELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDA 232
+ + +CPE D NEC P C + SC+NL GY C C PG+
Sbjct: 385 CVDQVDGFECICPEQWVGATCQLDANECEGKP--CLNAFSCKNLIGGYYCDCIPGWK--- 439
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT--RH-EPELQLCRDIDECEG--- 286
G+ I+ D GG C++ + CVCP G RH E E C G
Sbjct: 440 -GINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLC 498
Query: 287 ETETHYIESDYERGDIPPTFPTRTELA--SPCDNG-RCINTHGGFECECELGYVLDATAQ 343
E +G P +L SPC NG RC N G + C C D +
Sbjct: 499 EDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPD----DFGGK 554
Query: 344 RCLDNRR----GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK 399
C R G+C RV+DG C + A + G
Sbjct: 555 NCSVPREPCPGGAC--RVIDG-CGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDS 611
Query: 400 GFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
GF G C + +D+C L GGTC++ ++RC CP G + T P
Sbjct: 612 GFT---GTYCHENIDDC-LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNP 660
Score = 100 bits (240), Expect = 9e-21
Identities = 106/392 (27%), Positives = 163/392 (41%), Gaps = 70/392 (17%)
Query: 5 GMC-TNGICKNIDGG-FECICKPGYESGSEGALCRD-VDECRDNPRVCRRG-RCRNTAGS 60
G+C +G C + GG F CIC +SG G C + +D+C P CR G C + +
Sbjct: 589 GVCGPHGRCVSQPGGNFSCIC----DSGFTGTYCHENIDDCLGQP--CRNGGTCIDEVDA 642
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C C G+ + ++C D GRC + F C C+ G++
Sbjct: 643 FRCFCPSGWEGELCD--TNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR--- 697
Query: 121 VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-----GVSCQACPA 175
+C+ G C+++ +FRC C PG+ G TC K V+ C
Sbjct: 698 EFQCDAYTCSNGGTCYDSGDTFRCACPPGW----KGSTCAVAKNSSCLPNPCVNGGTCVG 753
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY-HPDAD 233
G+ ++ +C +G + N+C +P C +G C + +RC C PG+ PD
Sbjct: 754 SGAS-FSCICRDGWEGRTCTHNTNDCNPLP--CYNGGICVDGVNWFRCECAPGFAGPD-- 808
Query: 234 GLCR-DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
CR +IDEC S CA G C + + C CP G R P C+++
Sbjct: 809 --CRINIDEC--QSSPCAYGATCVDEINGYRCSCPPG-RAGPR---CQEV--------IG 852
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE--------CELGYVLDATA- 342
+ S + RG FP + C++ RC++ G +C C L +A +
Sbjct: 853 FGRSCWSRG---TPFPHGSSWVEDCNSCRCLD--GRRDCSKVWCGWKPCLLAGQPEALSA 907
Query: 343 -----QRCLDNRRGSCWRRVVD--GQCEAAAP 367
QRCL+ G C R + G+C A P
Sbjct: 908 QCPLGQRCLEKAPGQCLRPPCEAWGECGAEEP 939
>AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.
Length = 1218
Score = 130 bits (314), Expect = 1e-29
Identities = 130/465 (27%), Positives = 194/465 (41%), Gaps = 64/465 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-CRDNPRVCR-RGRCRNTAGS 60
NGG C+N ++C C GY G C + C +P C RG C+ T+
Sbjct: 308 NGGTCSN----TGPDKYQCSCPEGYS----GPNCEIAEHACLSDP--CHNRGSCKETSLG 357
Query: 61 YTCLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC- 118
+ C C PG+ PT + ++D+C+ ++ GG C + F+CVC P T C
Sbjct: 358 FECECSPGWTGPTCS---TNIDDCSPNNCSHGGTCQDLVNGFKCVCP----PQWTGKTCQ 410
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPA 175
+D +ECE + C N S+ C+CLPG+ N + CLG + SC+
Sbjct: 411 LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLG-QCQNDASCRDL-V 468
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL 235
G Y +CP G + D+ DI+EC + P G C+N ++C+C G+ + L
Sbjct: 469 NG---YRCICPPGYAGDHCERDIDECASNP-CLDGGHCQNEINRFQCLCPTGF---SGNL 521
Query: 236 CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI-DECEGETETHYI 293
C+ DID C+ + G QC N A + C CPE + E + C + D C T I
Sbjct: 522 CQLDIDYCEPNPCQ-NGAQCYNRASDYFCKCPE----DYEGKNCSHLKDHCR-TTPCEVI 575
Query: 294 ES---DYERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGYV---LDATAQRC 345
+S D P R ++ C +G+C + GG F C+C G+ C
Sbjct: 576 DSCTVAMASNDTPE--GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC 633
Query: 346 LDN---RRGSCWRRVVDGQC------EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
N G+C V +C E A E + +C + G+
Sbjct: 634 ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-NDCSQNPCHNGGTCRDLVNDFYCD 692
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G+ G TC D A GGTC + +++C CP G
Sbjct: 693 CKNGW---KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Score = 120 bits (290), Expect = 8e-27
Identities = 124/464 (26%), Positives = 193/464 (41%), Gaps = 64/464 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNTAGSYTC 63
C N CKN+ + C C PG+ G C ++++C C+ CR+ Y C
Sbjct: 421 CVNAKSCKNLIASYYCDCLPGWM----GQNCDININDCLGQ---CQNDASCRDLVNGYRC 473
Query: 64 LCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PG+A +C D+DECA++ GG C N FQC+C G+ + +D+D
Sbjct: 474 ICPPGYA---GDHCERDIDECASNPCLDGGHCQNEINRFQCLCPTGFSGNLCQ---LDID 527
Query: 123 ECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
C E C+NG +C+N + C+C + +G+ C LK C+ P + +
Sbjct: 528 YC-EPNPCQNGAQCYNRASDYFCKCPEDY----EGKNCSHLK----DHCRTTPCEVIDSC 578
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRD-I 239
V + + G I+ + V G PHG C++ G + C C+ G+ C + I
Sbjct: 579 TVAMASNDTPE-GVRYIS--SNVCG--PHGKCKSQSGGKFTCDCNKGF---TGTYCHENI 630
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETETHYIES- 295
++C+ + GG C + S+ C+C EG E + C G T +
Sbjct: 631 NDCESNPCR-NGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDF 689
Query: 296 --DYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGY----VLDATAQRCL 346
D + G T +R + C+N G C + F+C C G+ A CL
Sbjct: 690 YCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 347 DNRRGSCWRRVVDGQ-----CEAAAPELLLRQ---ECCCSVGLAWGSXXXXXXXXXXXXX 398
N + VV+G+ C+ + Q +C G+
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECA 809
Query: 399 KGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR +++EC S+ G TCV+ YRC CPPG
Sbjct: 810 PGFA---GPDCRININECQ-SSPCAFGATCVDEINGYRCVCPPG 849
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/230 (27%), Positives = 94/230 (40%), Gaps = 23/230 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ ++CIC G+E GA C ++++C NP C G CR+
Sbjct: 640 NGGTCIDGV-----NSYKCICSDGWE----GAYCETNINDCSQNP--CHNGGTCRDLVND 688
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACV 119
+ C C+ G+ C D ++ C GG C + +F+C+C G+ T A
Sbjct: 689 FYCDCKNGWKGKT---CHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA-- 743
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C G C SF C C G+ + + C G
Sbjct: 744 RNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTC-VDGDN 802
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY 228
Y C G + + +INEC + P C G+ C + GYRC+C PG+
Sbjct: 803 WYRCECAPGFAGPDCRININECQSSP--CAFGATCVDEINGYRCVCPPGH 850
Score = 73.7 bits (173), Expect = 1e-12
Identities = 71/281 (25%), Positives = 110/281 (39%), Gaps = 45/281 (16%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
C NG C+++ F C CK G++ G C D D G C + ++ C+C
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC 731
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
G+ T + C + GG CV + SF CVC+ G+ + ++C
Sbjct: 732 PGGWEGTTCNIARN-SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPI---CAQNTNDCS 787
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFT------LSND--------GRTCLGLKLGW----- 166
+G C + +RCEC PGF N+ G TC+ G+
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 847
Query: 167 ----GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR- 221
G CQ + + P+G D+ D N C + G +C + G R
Sbjct: 848 PGHSGAKCQEVSGRPCITMGSVIPDGAKWDD---DCNTCQCLNGRI---ACSKVWCGPRP 901
Query: 222 CICDPGYHPDADG-LCRDI--DECDMHQSYCAG-GQCRNTA 258
C+ G+ G C I D+C +H C G G+CR+++
Sbjct: 902 CLLHKGHSECPSGQSCIPILDDQCFVHP--CTGVGECRSSS 940
Score = 68.1 bits (159), Expect = 6e-11
Identities = 78/277 (28%), Positives = 112/277 (40%), Gaps = 45/277 (16%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQ 253
G ++C PG C HG C EP ++C+C+ + LC +D++ C HQ GG
Sbjct: 259 GLYCDKCIPHPG-CVHGICN--EP-WQCLCETNW---GGQLCDKDLNYCGTHQPCLNGGT 311
Query: 254 CRNTA-GSFTCVCPEG--------TRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C NT + C CPEG H C + C+ ET + E + G P
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK-ETSLGF-ECECSPGWTGP 369
Query: 305 TFPTRTELASP--CDN-GRCINTHGGFECECELGYV-----LDAT---AQRCLDNRRGSC 353
T T + SP C + G C + GF+C C + LDA A+ C++ + SC
Sbjct: 370 TCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAK--SC 427
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWG------SXXXXXXXXXXXXXKGFAKLDGA 407
+ C+ + Q C ++ G S G+A G
Sbjct: 428 KNLIASYYCDCLPG--WMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYA---GD 482
Query: 408 TC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
C RD+DECA S GG C N ++C CP G +
Sbjct: 483 HCERDIDECA-SNPCLDGGHCQNEINRFQCLCPTGFS 518
Score = 60.1 bits (139), Expect = 2e-08
Identities = 80/332 (24%), Positives = 119/332 (35%), Gaps = 56/332 (16%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
D+C C +G C N P CE G L + G ++ C G + Y
Sbjct: 263 DKCIPHPGCVHGIC-NEPWQCLCETNWGGQLCDKDLNYCGTHQPC-LNGGTCSNTGPDKY 320
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDID 240
CPEG S N +I E + C + GSC+ G+ C C PG+ +ID
Sbjct: 321 QCSCPEGYSGPN--CEIAEHACLSDPCHNRGSCKETSLGFECECSPGW--TGPTCSTNID 376
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCP--------EGTRHEPELQLCRDIDECEGETETH 291
+C + C+ GG C++ F CVCP + +E E + C + C+ ++
Sbjct: 377 DCSPNN--CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASY 434
Query: 292 YIESDYERGDIPPTFPTR-TELASPCDN-GRCINTHGGFECECELGYVLDATAQRCLDNR 349
Y D G + + C N C + G+ C C GY D + +
Sbjct: 435 YC--DCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECA 492
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
C + G C+ + R +C C G + G C
Sbjct: 493 SNPC---LDGGHCQNE----INRFQCLCPTGFS-----------------------GNLC 522
Query: 410 R-DVDECALSAELCAGGT-CVNTDGSYRCDCP 439
+ D+D C + C G C N Y C CP
Sbjct: 523 QLDIDYCEPNP--CQNGAQCYNRASDYFCKCP 552
>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
protein.
Length = 1214
Score = 130 bits (313), Expect = 1e-29
Identities = 130/465 (27%), Positives = 194/465 (41%), Gaps = 64/465 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-CRDNPRVCR-RGRCRNTAGS 60
NGG C+N ++C C GY G C + C +P C RG C+ T+
Sbjct: 295 NGGTCSN----TGPDKYQCSCPEGYS----GPNCEIAEHACLSDP--CHNRGSCKETSLG 344
Query: 61 YTCLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC- 118
+ C C PG+ PT + ++D+C+ ++ GG C + F+CVC P T C
Sbjct: 345 FECECSPGWTGPTCS---TNIDDCSPNNCSHGGTCQDLVNGFKCVCP----PQWTGKTCQ 397
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPA 175
+D +ECE + C N S+ C+CLPG+ N + CLG + SC+
Sbjct: 398 LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLG-QCQNDASCRDL-V 455
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL 235
G Y +CP G + D+ DI+EC + P G C+N ++C+C G+ + L
Sbjct: 456 NG---YRCICPPGYAGDHCERDIDECASNP-CLNGGHCQNEINRFQCLCPTGF---SGNL 508
Query: 236 CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI-DECEGETETHYI 293
C+ DID C+ + G QC N A + C CPE + E + C + D C T I
Sbjct: 509 CQLDIDYCEPNPCQ-NGAQCYNRASDYFCKCPE----DYEGKNCSHLKDHCR-TTPCEVI 562
Query: 294 ES---DYERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGYV---LDATAQRC 345
+S D P R ++ C +G+C + GG F C+C G+ C
Sbjct: 563 DSCTVAMASNDTPE--GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC 620
Query: 346 LDN---RRGSCWRRVVDGQC------EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
N G+C V +C E A E + +C + G+
Sbjct: 621 ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-NDCSQNPCHNGGTCRDLVNDFYCD 679
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G+ G TC D A GGTC + +++C CP G
Sbjct: 680 CKNGW---KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGG 721
Score = 121 bits (291), Expect = 6e-27
Identities = 124/464 (26%), Positives = 193/464 (41%), Gaps = 64/464 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNTAGSYTC 63
C N CKN+ + C C PG+ G C ++++C C+ CR+ Y C
Sbjct: 408 CVNAKSCKNLIASYYCDCLPGWM----GQNCDININDCLGQ---CQNDASCRDLVNGYRC 460
Query: 64 LCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PG+A +C D+DECA++ GG C N FQC+C G+ + +D+D
Sbjct: 461 ICPPGYA---GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ---LDID 514
Query: 123 ECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
C E C+NG +C+N + C+C + +G+ C LK C+ P + +
Sbjct: 515 YC-EPNPCQNGAQCYNRASDYFCKCPEDY----EGKNCSHLK----DHCRTTPCEVIDSC 565
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRD-I 239
V + + G I+ + V G PHG C++ G + C C+ G+ C + I
Sbjct: 566 TVAMASNDTPE-GVRYIS--SNVCG--PHGKCKSQSGGKFTCDCNKGF---TGTYCHENI 617
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETETHYIES- 295
++C+ + GG C + S+ C+C EG E + C G T +
Sbjct: 618 NDCESNPCR-NGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDF 676
Query: 296 --DYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGY----VLDATAQRCL 346
D + G T +R + C+N G C + F+C C G+ A CL
Sbjct: 677 YCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 736
Query: 347 DNRRGSCWRRVVDGQ-----CEAAAPELLLRQ---ECCCSVGLAWGSXXXXXXXXXXXXX 398
N + VV+G+ C+ + Q +C G+
Sbjct: 737 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECA 796
Query: 399 KGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR +++EC S+ G TCV+ YRC CPPG
Sbjct: 797 PGFA---GPDCRININECQ-SSPCAFGATCVDEINGYRCVCPPG 836
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/230 (27%), Positives = 94/230 (40%), Gaps = 23/230 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ ++CIC G+E GA C ++++C NP C G CR+
Sbjct: 627 NGGTCIDGV-----NSYKCICSDGWE----GAYCETNINDCSQNP--CHNGGTCRDLVND 675
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACV 119
+ C C+ G+ C D ++ C GG C + +F+C+C G+ T A
Sbjct: 676 FYCDCKNGWKGKT---CHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA-- 730
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C G C SF C C G+ + + C G
Sbjct: 731 RNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTC-VDGDN 789
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY 228
Y C G + + +INEC + P C G+ C + GYRC+C PG+
Sbjct: 790 WYRCECAPGFAGPDCRININECQSSP--CAFGATCVDEINGYRCVCPPGH 837
Score = 73.7 bits (173), Expect = 1e-12
Identities = 71/281 (25%), Positives = 110/281 (39%), Gaps = 45/281 (16%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
C NG C+++ F C CK G++ G C D D G C + ++ C+C
Sbjct: 663 CHNGGTCRDLVNDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC 718
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
G+ T + C + GG CV + SF CVC+ G+ + ++C
Sbjct: 719 PGGWEGTTCNIARN-SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPI---CAQNTNDCS 774
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFT------LSND--------GRTCLGLKLGW----- 166
+G C + +RCEC PGF N+ G TC+ G+
Sbjct: 775 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 834
Query: 167 ----GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR- 221
G CQ + + P+G D+ D N C + G +C + G R
Sbjct: 835 PGHSGAKCQEVSGRPCITMGSVIPDGAKWDD---DCNTCQCLNGRI---ACSKVWCGPRP 888
Query: 222 CICDPGYHPDADG-LCRDI--DECDMHQSYCAG-GQCRNTA 258
C+ G+ G C I D+C +H C G G+CR+++
Sbjct: 889 CLLHKGHSECPSGQSCIPILDDQCFVHP--CTGVGECRSSS 927
Score = 68.1 bits (159), Expect = 6e-11
Identities = 78/277 (28%), Positives = 112/277 (40%), Gaps = 45/277 (16%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQ 253
G ++C PG C HG C EP ++C+C+ + LC +D++ C HQ GG
Sbjct: 246 GLYCDKCIPHPG-CVHGICN--EP-WQCLCETNW---GGQLCDKDLNYCGTHQPCLNGGT 298
Query: 254 CRNTA-GSFTCVCPEG--------TRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C NT + C CPEG H C + C+ ET + E + G P
Sbjct: 299 CSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK-ETSLGF-ECECSPGWTGP 356
Query: 305 TFPTRTELASP--CDN-GRCINTHGGFECECELGYV-----LDAT---AQRCLDNRRGSC 353
T T + SP C + G C + GF+C C + LDA A+ C++ + SC
Sbjct: 357 TCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAK--SC 414
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWG------SXXXXXXXXXXXXXKGFAKLDGA 407
+ C+ + Q C ++ G S G+A G
Sbjct: 415 KNLIASYYCDCLPG--WMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYA---GD 469
Query: 408 TC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
C RD+DECA S GG C N ++C CP G +
Sbjct: 470 HCERDIDECA-SNPCLNGGHCQNEINRFQCLCPTGFS 505
Score = 60.1 bits (139), Expect = 2e-08
Identities = 80/332 (24%), Positives = 118/332 (35%), Gaps = 56/332 (16%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
D+C C +G C N P CE G L + G ++ C G + Y
Sbjct: 250 DKCIPHPGCVHGIC-NEPWQCLCETNWGGQLCDKDLNYCGTHQPC-LNGGTCSNTGPDKY 307
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDID 240
CPEG S N +I E + C + GSC+ G+ C C PG+ +ID
Sbjct: 308 QCSCPEGYSGPN--CEIAEHACLSDPCHNRGSCKETSLGFECECSPGW--TGPTCSTNID 363
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCP--------EGTRHEPELQLCRDIDECEGETETH 291
+C + C+ GG C++ F CVCP + +E E + C + C+ ++
Sbjct: 364 DCSPNN--CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASY 421
Query: 292 YIESDYERGDIPPTFPTR-TELASPCDN-GRCINTHGGFECECELGYVLDATAQRCLDNR 349
Y D G + + C N C + G+ C C GY D + +
Sbjct: 422 YC--DCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECA 479
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
C G C+ + R +C C G + G C
Sbjct: 480 SNPCLN---GGHCQNE----INRFQCLCPTGFS-----------------------GNLC 509
Query: 410 R-DVDECALSAELCAGGT-CVNTDGSYRCDCP 439
+ D+D C + C G C N Y C CP
Sbjct: 510 QLDIDYCEPNP--CQNGAQCYNRASDYFCKCP 539
>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
Length = 1218
Score = 130 bits (313), Expect = 1e-29
Identities = 130/465 (27%), Positives = 194/465 (41%), Gaps = 64/465 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-CRDNPRVCR-RGRCRNTAGS 60
NGG C+N ++C C GY G C + C +P C RG C+ T+
Sbjct: 308 NGGTCSN----TGPDKYQCSCPEGYS----GPNCEIAEHACLSDP--CHNRGSCKETSLG 357
Query: 61 YTCLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC- 118
+ C C PG+ PT + ++D+C+ ++ GG C + F+CVC P T C
Sbjct: 358 FECECSPGWTGPTCS---TNIDDCSPNNCSHGGTCQDLVNGFKCVCP----PQWTGKTCQ 410
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPA 175
+D +ECE + C N S+ C+CLPG+ N + CLG + SC+
Sbjct: 411 LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLG-QCQNDASCRDL-V 468
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL 235
G Y +CP G + D+ DI+EC + P G C+N ++C+C G+ + L
Sbjct: 469 NG---YRCICPPGYAGDHCERDIDECASNP-CLNGGHCQNEINRFQCLCPTGF---SGNL 521
Query: 236 CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI-DECEGETETHYI 293
C+ DID C+ + G QC N A + C CPE + E + C + D C T I
Sbjct: 522 CQLDIDYCEPNPCQ-NGAQCYNRASDYFCKCPE----DYEGKNCSHLKDHCR-TTPCEVI 575
Query: 294 ES---DYERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGYV---LDATAQRC 345
+S D P R ++ C +G+C + GG F C+C G+ C
Sbjct: 576 DSCTVAMASNDTPE--GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC 633
Query: 346 LDN---RRGSCWRRVVDGQC------EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
N G+C V +C E A E + +C + G+
Sbjct: 634 ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-NDCSQNPCHNGGTCRDLVNDFYCD 692
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G+ G TC D A GGTC + +++C CP G
Sbjct: 693 CKNGW---KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Score = 121 bits (291), Expect = 6e-27
Identities = 124/464 (26%), Positives = 193/464 (41%), Gaps = 64/464 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNTAGSYTC 63
C N CKN+ + C C PG+ G C ++++C C+ CR+ Y C
Sbjct: 421 CVNAKSCKNLIASYYCDCLPGWM----GQNCDININDCLGQ---CQNDASCRDLVNGYRC 473
Query: 64 LCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PG+A +C D+DECA++ GG C N FQC+C G+ + +D+D
Sbjct: 474 ICPPGYA---GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ---LDID 527
Query: 123 ECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
C E C+NG +C+N + C+C + +G+ C LK C+ P + +
Sbjct: 528 YC-EPNPCQNGAQCYNRASDYFCKCPEDY----EGKNCSHLK----DHCRTTPCEVIDSC 578
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRD-I 239
V + + G I+ + V G PHG C++ G + C C+ G+ C + I
Sbjct: 579 TVAMASNDTPE-GVRYIS--SNVCG--PHGKCKSQSGGKFTCDCNKGF---TGTYCHENI 630
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETETHYIES- 295
++C+ + GG C + S+ C+C EG E + C G T +
Sbjct: 631 NDCESNPCR-NGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDF 689
Query: 296 --DYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGY----VLDATAQRCL 346
D + G T +R + C+N G C + F+C C G+ A CL
Sbjct: 690 YCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 347 DNRRGSCWRRVVDGQ-----CEAAAPELLLRQ---ECCCSVGLAWGSXXXXXXXXXXXXX 398
N + VV+G+ C+ + Q +C G+
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECA 809
Query: 399 KGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR +++EC S+ G TCV+ YRC CPPG
Sbjct: 810 PGFA---GPDCRININECQ-SSPCAFGATCVDEINGYRCVCPPG 849
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/230 (27%), Positives = 94/230 (40%), Gaps = 23/230 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ ++CIC G+E GA C ++++C NP C G CR+
Sbjct: 640 NGGTCIDGV-----NSYKCICSDGWE----GAYCETNINDCSQNP--CHNGGTCRDLVND 688
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACV 119
+ C C+ G+ C D ++ C GG C + +F+C+C G+ T A
Sbjct: 689 FYCDCKNGWKGKT---CHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA-- 743
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C G C SF C C G+ + + C G
Sbjct: 744 RNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTC-VDGDN 802
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY 228
Y C G + + +INEC + P C G+ C + GYRC+C PG+
Sbjct: 803 WYRCECAPGFAGPDCRININECQSSP--CAFGATCVDEINGYRCVCPPGH 850
Score = 73.7 bits (173), Expect = 1e-12
Identities = 71/281 (25%), Positives = 110/281 (39%), Gaps = 45/281 (16%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
C NG C+++ F C CK G++ G C D D G C + ++ C+C
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC 731
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
G+ T + C + GG CV + SF CVC+ G+ + ++C
Sbjct: 732 PGGWEGTTCNIARN-SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPI---CAQNTNDCS 787
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFT------LSND--------GRTCLGLKLGW----- 166
+G C + +RCEC PGF N+ G TC+ G+
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 847
Query: 167 ----GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR- 221
G CQ + + P+G D+ D N C + G +C + G R
Sbjct: 848 PGHSGAKCQEVSGRPCITMGSVIPDGAKWDD---DCNTCQCLNGRI---ACSKVWCGPRP 901
Query: 222 CICDPGYHPDADG-LCRDI--DECDMHQSYCAG-GQCRNTA 258
C+ G+ G C I D+C +H C G G+CR+++
Sbjct: 902 CLLHKGHSECPSGQSCIPILDDQCFVHP--CTGVGECRSSS 940
Score = 68.1 bits (159), Expect = 6e-11
Identities = 78/277 (28%), Positives = 112/277 (40%), Gaps = 45/277 (16%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQ 253
G ++C PG C HG C EP ++C+C+ + LC +D++ C HQ GG
Sbjct: 259 GLYCDKCIPHPG-CVHGICN--EP-WQCLCETNW---GGQLCDKDLNYCGTHQPCLNGGT 311
Query: 254 CRNTA-GSFTCVCPEG--------TRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C NT + C CPEG H C + C+ ET + E + G P
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK-ETSLGF-ECECSPGWTGP 369
Query: 305 TFPTRTELASP--CDN-GRCINTHGGFECECELGYV-----LDAT---AQRCLDNRRGSC 353
T T + SP C + G C + GF+C C + LDA A+ C++ + SC
Sbjct: 370 TCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAK--SC 427
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWG------SXXXXXXXXXXXXXKGFAKLDGA 407
+ C+ + Q C ++ G S G+A G
Sbjct: 428 KNLIASYYCDCLPG--WMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYA---GD 482
Query: 408 TC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
C RD+DECA S GG C N ++C CP G +
Sbjct: 483 HCERDIDECA-SNPCLNGGHCQNEINRFQCLCPTGFS 518
Score = 60.1 bits (139), Expect = 2e-08
Identities = 80/332 (24%), Positives = 118/332 (35%), Gaps = 56/332 (16%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
D+C C +G C N P CE G L + G ++ C G + Y
Sbjct: 263 DKCIPHPGCVHGIC-NEPWQCLCETNWGGQLCDKDLNYCGTHQPC-LNGGTCSNTGPDKY 320
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDID 240
CPEG S N +I E + C + GSC+ G+ C C PG+ +ID
Sbjct: 321 QCSCPEGYSGPN--CEIAEHACLSDPCHNRGSCKETSLGFECECSPGW--TGPTCSTNID 376
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCP--------EGTRHEPELQLCRDIDECEGETETH 291
+C + C+ GG C++ F CVCP + +E E + C + C+ ++
Sbjct: 377 DCSPNN--CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASY 434
Query: 292 YIESDYERGDIPPTFPTR-TELASPCDN-GRCINTHGGFECECELGYVLDATAQRCLDNR 349
Y D G + + C N C + G+ C C GY D + +
Sbjct: 435 YC--DCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECA 492
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
C G C+ + R +C C G + G C
Sbjct: 493 SNPCLN---GGHCQNE----INRFQCLCPTGFS-----------------------GNLC 522
Query: 410 R-DVDECALSAELCAGGT-CVNTDGSYRCDCP 439
+ D+D C + C G C N Y C CP
Sbjct: 523 QLDIDYCEPNP--CQNGAQCYNRASDYFCKCP 552
>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged
1 protein.
Length = 1218
Score = 130 bits (313), Expect = 1e-29
Identities = 130/465 (27%), Positives = 194/465 (41%), Gaps = 64/465 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-CRDNPRVCR-RGRCRNTAGS 60
NGG C+N ++C C GY G C + C +P C RG C+ T+
Sbjct: 308 NGGTCSN----TGPDKYQCSCPEGYS----GPNCEIAEHACLSDP--CHNRGSCKETSLG 357
Query: 61 YTCLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC- 118
+ C C PG+ PT + ++D+C+ ++ GG C + F+CVC P T C
Sbjct: 358 FECECSPGWTGPTCS---TNIDDCSPNNCSHGGTCQDLVNGFKCVCP----PQWTGKTCQ 410
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPA 175
+D +ECE + C N S+ C+CLPG+ N + CLG + SC+
Sbjct: 411 LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLG-QCQNDASCRDL-V 468
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL 235
G Y +CP G + D+ DI+EC + P G C+N ++C+C G+ + L
Sbjct: 469 NG---YRCICPPGYAGDHCERDIDECASNP-CLNGGHCQNEINRFQCLCPTGF---SGNL 521
Query: 236 CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI-DECEGETETHYI 293
C+ DID C+ + G QC N A + C CPE + E + C + D C T I
Sbjct: 522 CQLDIDYCEPNPCQ-NGAQCYNRASDYFCKCPE----DYEGKNCSHLKDHCR-TTPCEVI 575
Query: 294 ES---DYERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGYV---LDATAQRC 345
+S D P R ++ C +G+C + GG F C+C G+ C
Sbjct: 576 DSCTVAMASNDTPE--GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC 633
Query: 346 LDN---RRGSCWRRVVDGQC------EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
N G+C V +C E A E + +C + G+
Sbjct: 634 ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-NDCSQNPCHNGGTCRDLVNDFYCD 692
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G+ G TC D A GGTC + +++C CP G
Sbjct: 693 CKNGW---KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Score = 121 bits (291), Expect = 6e-27
Identities = 124/464 (26%), Positives = 193/464 (41%), Gaps = 64/464 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNTAGSYTC 63
C N CKN+ + C C PG+ G C ++++C C+ CR+ Y C
Sbjct: 421 CVNAKSCKNLIASYYCDCLPGWM----GQNCDININDCLGQ---CQNDASCRDLVNGYRC 473
Query: 64 LCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PG+A +C D+DECA++ GG C N FQC+C G+ + +D+D
Sbjct: 474 ICPPGYA---GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ---LDID 527
Query: 123 ECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
C E C+NG +C+N + C+C + +G+ C LK C+ P + +
Sbjct: 528 YC-EPNPCQNGAQCYNRASDYFCKCPEDY----EGKNCSHLK----DHCRTTPCEVIDSC 578
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRD-I 239
V + + G I+ + V G PHG C++ G + C C+ G+ C + I
Sbjct: 579 TVAMASNDTPE-GVRYIS--SNVCG--PHGKCKSQSGGKFTCDCNKGF---TGTYCHENI 630
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETETHYIES- 295
++C+ + GG C + S+ C+C EG E + C G T +
Sbjct: 631 NDCESNPCR-NGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDF 689
Query: 296 --DYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGY----VLDATAQRCL 346
D + G T +R + C+N G C + F+C C G+ A CL
Sbjct: 690 YCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 347 DNRRGSCWRRVVDGQ-----CEAAAPELLLRQ---ECCCSVGLAWGSXXXXXXXXXXXXX 398
N + VV+G+ C+ + Q +C G+
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECA 809
Query: 399 KGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR +++EC S+ G TCV+ YRC CPPG
Sbjct: 810 PGFA---GPDCRININECQ-SSPCAFGATCVDEINGYRCVCPPG 849
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/230 (27%), Positives = 94/230 (40%), Gaps = 23/230 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ ++CIC G+E GA C ++++C NP C G CR+
Sbjct: 640 NGGTCIDGV-----NSYKCICSDGWE----GAYCETNINDCSQNP--CHNGGTCRDLVND 688
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACV 119
+ C C+ G+ C D ++ C GG C + +F+C+C G+ T A
Sbjct: 689 FYCDCKNGWKGKT---CHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA-- 743
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C G C SF C C G+ + + C G
Sbjct: 744 RNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTC-VDGDN 802
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY 228
Y C G + + +INEC + P C G+ C + GYRC+C PG+
Sbjct: 803 WYRCECAPGFAGPDCRININECQSSP--CAFGATCVDEINGYRCVCPPGH 850
Score = 73.7 bits (173), Expect = 1e-12
Identities = 71/281 (25%), Positives = 110/281 (39%), Gaps = 45/281 (16%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
C NG C+++ F C CK G++ G C D D G C + ++ C+C
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC 731
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
G+ T + C + GG CV + SF CVC+ G+ + ++C
Sbjct: 732 PGGWEGTTCNIARN-SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPI---CAQNTNDCS 787
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFT------LSND--------GRTCLGLKLGW----- 166
+G C + +RCEC PGF N+ G TC+ G+
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 847
Query: 167 ----GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR- 221
G CQ + + P+G D+ D N C + G +C + G R
Sbjct: 848 PGHSGAKCQEVSGRPCITMGSVIPDGAKWDD---DCNTCQCLNGRI---ACSKVWCGPRP 901
Query: 222 CICDPGYHPDADG-LCRDI--DECDMHQSYCAG-GQCRNTA 258
C+ G+ G C I D+C +H C G G+CR+++
Sbjct: 902 CLLHKGHSECPSGQSCIPILDDQCFVHP--CTGVGECRSSS 940
Score = 68.1 bits (159), Expect = 6e-11
Identities = 78/277 (28%), Positives = 112/277 (40%), Gaps = 45/277 (16%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQ 253
G ++C PG C HG C EP ++C+C+ + LC +D++ C HQ GG
Sbjct: 259 GLYCDKCIPHPG-CVHGICN--EP-WQCLCETNW---GGQLCDKDLNYCGTHQPCLNGGT 311
Query: 254 CRNTA-GSFTCVCPEG--------TRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C NT + C CPEG H C + C+ ET + E + G P
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK-ETSLGF-ECECSPGWTGP 369
Query: 305 TFPTRTELASP--CDN-GRCINTHGGFECECELGYV-----LDAT---AQRCLDNRRGSC 353
T T + SP C + G C + GF+C C + LDA A+ C++ + SC
Sbjct: 370 TCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAK--SC 427
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWG------SXXXXXXXXXXXXXKGFAKLDGA 407
+ C+ + Q C ++ G S G+A G
Sbjct: 428 KNLIASYYCDCLPG--WMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYA---GD 482
Query: 408 TC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
C RD+DECA S GG C N ++C CP G +
Sbjct: 483 HCERDIDECA-SNPCLNGGHCQNEINRFQCLCPTGFS 518
Score = 60.1 bits (139), Expect = 2e-08
Identities = 80/332 (24%), Positives = 118/332 (35%), Gaps = 56/332 (16%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
D+C C +G C N P CE G L + G ++ C G + Y
Sbjct: 263 DKCIPHPGCVHGIC-NEPWQCLCETNWGGQLCDKDLNYCGTHQPC-LNGGTCSNTGPDKY 320
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDID 240
CPEG S N +I E + C + GSC+ G+ C C PG+ +ID
Sbjct: 321 QCSCPEGYSGPN--CEIAEHACLSDPCHNRGSCKETSLGFECECSPGW--TGPTCSTNID 376
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCP--------EGTRHEPELQLCRDIDECEGETETH 291
+C + C+ GG C++ F CVCP + +E E + C + C+ ++
Sbjct: 377 DCSPNN--CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASY 434
Query: 292 YIESDYERGDIPPTFPTR-TELASPCDN-GRCINTHGGFECECELGYVLDATAQRCLDNR 349
Y D G + + C N C + G+ C C GY D + +
Sbjct: 435 YC--DCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECA 492
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
C G C+ + R +C C G + G C
Sbjct: 493 SNPCLN---GGHCQNE----INRFQCLCPTGFS-----------------------GNLC 522
Query: 410 R-DVDECALSAELCAGGT-CVNTDGSYRCDCP 439
+ D+D C + C G C N Y C CP
Sbjct: 523 QLDIDYCEPNP--CQNGAQCYNRASDYFCKCP 552
>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 130 bits (313), Expect = 1e-29
Identities = 130/465 (27%), Positives = 194/465 (41%), Gaps = 64/465 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-CRDNPRVCR-RGRCRNTAGS 60
NGG C+N ++C C GY G C + C +P C RG C+ T+
Sbjct: 308 NGGTCSN----TGPDKYQCSCPEGYS----GPNCEIAEHACLSDP--CHNRGSCKETSLG 357
Query: 61 YTCLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC- 118
+ C C PG+ PT + ++D+C+ ++ GG C + F+CVC P T C
Sbjct: 358 FECECSPGWTGPTCS---TNIDDCSPNNCSHGGTCQDLVNGFKCVCP----PQWTGKTCQ 410
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPA 175
+D +ECE + C N S+ C+CLPG+ N + CLG + SC+
Sbjct: 411 LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLG-QCQNDASCRDL-V 468
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL 235
G Y +CP G + D+ DI+EC + P G C+N ++C+C G+ + L
Sbjct: 469 NG---YRCICPPGYAGDHCERDIDECASNP-CLNGGHCQNEINRFQCLCPTGF---SGNL 521
Query: 236 CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI-DECEGETETHYI 293
C+ DID C+ + G QC N A + C CPE + E + C + D C T I
Sbjct: 522 CQLDIDYCEPNPCQ-NGAQCYNRASDYFCKCPE----DYEGKNCSHLKDHCR-TTPCEVI 575
Query: 294 ES---DYERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGYV---LDATAQRC 345
+S D P R ++ C +G+C + GG F C+C G+ C
Sbjct: 576 DSCTVAMASNDTPE--GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC 633
Query: 346 LDN---RRGSCWRRVVDGQC------EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
N G+C V +C E A E + +C + G+
Sbjct: 634 ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-NDCSQNPCHNGGTCRDLVNDFYCD 692
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G+ G TC D A GGTC + +++C CP G
Sbjct: 693 CKNGW---KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Score = 121 bits (291), Expect = 6e-27
Identities = 124/464 (26%), Positives = 193/464 (41%), Gaps = 64/464 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNTAGSYTC 63
C N CKN+ + C C PG+ G C ++++C C+ CR+ Y C
Sbjct: 421 CVNAKSCKNLIASYYCDCLPGWM----GQNCDININDCLGQ---CQNDASCRDLVNGYRC 473
Query: 64 LCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PG+A +C D+DECA++ GG C N FQC+C G+ + +D+D
Sbjct: 474 ICPPGYA---GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ---LDID 527
Query: 123 ECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
C E C+NG +C+N + C+C + +G+ C LK C+ P + +
Sbjct: 528 YC-EPNPCQNGAQCYNRASDYFCKCPEDY----EGKNCSHLK----DHCRTTPCEVIDSC 578
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRD-I 239
V + + G I+ + V G PHG C++ G + C C+ G+ C + I
Sbjct: 579 TVAMASNDTPE-GVRYIS--SNVCG--PHGKCKSQSGGKFTCDCNKGF---TGTYCHENI 630
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETETHYIES- 295
++C+ + GG C + S+ C+C EG E + C G T +
Sbjct: 631 NDCESNPCR-NGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDF 689
Query: 296 --DYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGY----VLDATAQRCL 346
D + G T +R + C+N G C + F+C C G+ A CL
Sbjct: 690 YCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 347 DNRRGSCWRRVVDGQ-----CEAAAPELLLRQ---ECCCSVGLAWGSXXXXXXXXXXXXX 398
N + VV+G+ C+ + Q +C G+
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECA 809
Query: 399 KGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR +++EC S+ G TCV+ YRC CPPG
Sbjct: 810 PGFA---GPDCRININECQ-SSPCAFGATCVDEINGYRCVCPPG 849
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/230 (27%), Positives = 94/230 (40%), Gaps = 23/230 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ ++CIC G+E GA C ++++C NP C G CR+
Sbjct: 640 NGGTCIDGV-----NSYKCICSDGWE----GAYCETNINDCSQNP--CHNGGTCRDLVND 688
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACV 119
+ C C+ G+ C D ++ C GG C + +F+C+C G+ T A
Sbjct: 689 FYCDCKNGWKGKT---CHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA-- 743
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C G C SF C C G+ + + C G
Sbjct: 744 RNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTC-VDGDN 802
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY 228
Y C G + + +INEC + P C G+ C + GYRC+C PG+
Sbjct: 803 WYRCECAPGFAGPDCRININECQSSP--CAFGATCVDEINGYRCVCPPGH 850
Score = 73.7 bits (173), Expect = 1e-12
Identities = 71/281 (25%), Positives = 110/281 (39%), Gaps = 45/281 (16%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
C NG C+++ F C CK G++ G C D D G C + ++ C+C
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC 731
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
G+ T + C + GG CV + SF CVC+ G+ + ++C
Sbjct: 732 PGGWEGTTCNIARN-SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPI---CAQNTNDCS 787
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFT------LSND--------GRTCLGLKLGW----- 166
+G C + +RCEC PGF N+ G TC+ G+
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 847
Query: 167 ----GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR- 221
G CQ + + P+G D+ D N C + G +C + G R
Sbjct: 848 PGHSGAKCQEVSGRPCITMGSVIPDGAKWDD---DCNTCQCLNGRI---ACSKVWCGPRP 901
Query: 222 CICDPGYHPDADG-LCRDI--DECDMHQSYCAG-GQCRNTA 258
C+ G+ G C I D+C +H C G G+CR+++
Sbjct: 902 CLLHKGHSECPSGQSCIPILDDQCFVHP--CTGVGECRSSS 940
Score = 68.1 bits (159), Expect = 6e-11
Identities = 78/277 (28%), Positives = 112/277 (40%), Gaps = 45/277 (16%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQ 253
G ++C PG C HG C EP ++C+C+ + LC +D++ C HQ GG
Sbjct: 259 GLYCDKCIPHPG-CVHGICN--EP-WQCLCETNW---GGQLCDKDLNYCGTHQPCLNGGT 311
Query: 254 CRNTA-GSFTCVCPEG--------TRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C NT + C CPEG H C + C+ ET + E + G P
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK-ETSLGF-ECECSPGWTGP 369
Query: 305 TFPTRTELASP--CDN-GRCINTHGGFECECELGYV-----LDAT---AQRCLDNRRGSC 353
T T + SP C + G C + GF+C C + LDA A+ C++ + SC
Sbjct: 370 TCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAK--SC 427
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWG------SXXXXXXXXXXXXXKGFAKLDGA 407
+ C+ + Q C ++ G S G+A G
Sbjct: 428 KNLIASYYCDCLPG--WMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYA---GD 482
Query: 408 TC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
C RD+DECA S GG C N ++C CP G +
Sbjct: 483 HCERDIDECA-SNPCLNGGHCQNEINRFQCLCPTGFS 518
Score = 60.1 bits (139), Expect = 2e-08
Identities = 80/332 (24%), Positives = 118/332 (35%), Gaps = 56/332 (16%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
D+C C +G C N P CE G L + G ++ C G + Y
Sbjct: 263 DKCIPHPGCVHGIC-NEPWQCLCETNWGGQLCDKDLNYCGTHQPC-LNGGTCSNTGPDKY 320
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDID 240
CPEG S N +I E + C + GSC+ G+ C C PG+ +ID
Sbjct: 321 QCSCPEGYSGPN--CEIAEHACLSDPCHNRGSCKETSLGFECECSPGW--TGPTCSTNID 376
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCP--------EGTRHEPELQLCRDIDECEGETETH 291
+C + C+ GG C++ F CVCP + +E E + C + C+ ++
Sbjct: 377 DCSPNN--CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASY 434
Query: 292 YIESDYERGDIPPTFPTR-TELASPCDN-GRCINTHGGFECECELGYVLDATAQRCLDNR 349
Y D G + + C N C + G+ C C GY D + +
Sbjct: 435 YC--DCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECA 492
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
C G C+ + R +C C G + G C
Sbjct: 493 SNPCLN---GGHCQNE----INRFQCLCPTGFS-----------------------GNLC 522
Query: 410 R-DVDECALSAELCAGGT-CVNTDGSYRCDCP 439
+ D+D C + C G C N Y C CP
Sbjct: 523 QLDIDYCEPNP--CQNGAQCYNRASDYFCKCP 552
>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 130 bits (313), Expect = 1e-29
Identities = 130/465 (27%), Positives = 194/465 (41%), Gaps = 64/465 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-CRDNPRVCR-RGRCRNTAGS 60
NGG C+N ++C C GY G C + C +P C RG C+ T+
Sbjct: 308 NGGTCSN----TGPDKYQCSCPEGYS----GPNCEIAEHACLSDP--CHNRGSCKETSLG 357
Query: 61 YTCLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC- 118
+ C C PG+ PT + ++D+C+ ++ GG C + F+CVC P T C
Sbjct: 358 FECECSPGWTGPTCS---TNIDDCSPNNCSHGGTCQDLVNGFKCVCP----PQWTGKTCQ 410
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPA 175
+D +ECE + C N S+ C+CLPG+ N + CLG + SC+
Sbjct: 411 LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLG-QCQNDASCRDL-V 468
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL 235
G Y +CP G + D+ DI+EC + P G C+N ++C+C G+ + L
Sbjct: 469 NG---YRCICPPGYAGDHCERDIDECASNP-CLNGGHCQNEINRFQCLCPTGF---SGNL 521
Query: 236 CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI-DECEGETETHYI 293
C+ DID C+ + G QC N A + C CPE + E + C + D C T I
Sbjct: 522 CQLDIDYCEPNPCQ-NGAQCYNRASDYFCKCPE----DYEGKNCSHLKDHCR-TTPCEVI 575
Query: 294 ES---DYERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGYV---LDATAQRC 345
+S D P R ++ C +G+C + GG F C+C G+ C
Sbjct: 576 DSCTVAMASNDTPE--GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC 633
Query: 346 LDN---RRGSCWRRVVDGQC------EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
N G+C V +C E A E + +C + G+
Sbjct: 634 ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-NDCSQNPCHNGGTCRDLVNDFYCD 692
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G+ G TC D A GGTC + +++C CP G
Sbjct: 693 CKNGW---KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Score = 121 bits (291), Expect = 6e-27
Identities = 124/464 (26%), Positives = 193/464 (41%), Gaps = 64/464 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNTAGSYTC 63
C N CKN+ + C C PG+ G C ++++C C+ CR+ Y C
Sbjct: 421 CVNAKSCKNLIASYYCDCLPGWM----GQNCDININDCLGQ---CQNDASCRDLVNGYRC 473
Query: 64 LCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PG+A +C D+DECA++ GG C N FQC+C G+ + +D+D
Sbjct: 474 ICPPGYA---GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ---LDID 527
Query: 123 ECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
C E C+NG +C+N + C+C + +G+ C LK C+ P + +
Sbjct: 528 YC-EPNPCQNGAQCYNRASDYFCKCPEDY----EGKNCSHLK----DHCRTTPCEVIDSC 578
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRD-I 239
V + + G I+ + V G PHG C++ G + C C+ G+ C + I
Sbjct: 579 TVAMASNDTPE-GVRYIS--SNVCG--PHGKCKSQSGGKFTCDCNKGF---TGTYCHENI 630
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETETHYIES- 295
++C+ + GG C + S+ C+C EG E + C G T +
Sbjct: 631 NDCESNPCR-NGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDF 689
Query: 296 --DYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGY----VLDATAQRCL 346
D + G T +R + C+N G C + F+C C G+ A CL
Sbjct: 690 YCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 347 DNRRGSCWRRVVDGQ-----CEAAAPELLLRQ---ECCCSVGLAWGSXXXXXXXXXXXXX 398
N + VV+G+ C+ + Q +C G+
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECA 809
Query: 399 KGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR +++EC S+ G TCV+ YRC CPPG
Sbjct: 810 PGFA---GPDCRININECQ-SSPCAFGATCVDEINGYRCVCPPG 849
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/230 (27%), Positives = 94/230 (40%), Gaps = 23/230 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ ++CIC G+E GA C ++++C NP C G CR+
Sbjct: 640 NGGTCIDGV-----NSYKCICSDGWE----GAYCETNINDCSQNP--CHNGGTCRDLVND 688
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACV 119
+ C C+ G+ C D ++ C GG C + +F+C+C G+ T A
Sbjct: 689 FYCDCKNGWKGKT---CHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA-- 743
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C G C SF C C G+ + + C G
Sbjct: 744 RNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTC-VDGDN 802
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY 228
Y C G + + +INEC + P C G+ C + GYRC+C PG+
Sbjct: 803 WYRCECAPGFAGPDCRININECQSSP--CAFGATCVDEINGYRCVCPPGH 850
Score = 73.7 bits (173), Expect = 1e-12
Identities = 71/281 (25%), Positives = 110/281 (39%), Gaps = 45/281 (16%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
C NG C+++ F C CK G++ G C D D G C + ++ C+C
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC 731
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
G+ T + C + GG CV + SF CVC+ G+ + ++C
Sbjct: 732 PGGWEGTTCNIARN-SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPI---CAQNTNDCS 787
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFT------LSND--------GRTCLGLKLGW----- 166
+G C + +RCEC PGF N+ G TC+ G+
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 847
Query: 167 ----GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR- 221
G CQ + + P+G D+ D N C + G +C + G R
Sbjct: 848 PGHSGAKCQEVSGRPCITMGSVIPDGAKWDD---DCNTCQCLNGRI---ACSKVWCGPRP 901
Query: 222 CICDPGYHPDADG-LCRDI--DECDMHQSYCAG-GQCRNTA 258
C+ G+ G C I D+C +H C G G+CR+++
Sbjct: 902 CLLHKGHSECPSGQSCIPILDDQCFVHP--CTGVGECRSSS 940
Score = 68.1 bits (159), Expect = 6e-11
Identities = 78/277 (28%), Positives = 112/277 (40%), Gaps = 45/277 (16%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQ 253
G ++C PG C HG C EP ++C+C+ + LC +D++ C HQ GG
Sbjct: 259 GLYCDKCIPHPG-CVHGICN--EP-WQCLCETNW---GGQLCDKDLNYCGTHQPCLNGGT 311
Query: 254 CRNTA-GSFTCVCPEG--------TRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C NT + C CPEG H C + C+ ET + E + G P
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK-ETSLGF-ECECSPGWTGP 369
Query: 305 TFPTRTELASP--CDN-GRCINTHGGFECECELGYV-----LDAT---AQRCLDNRRGSC 353
T T + SP C + G C + GF+C C + LDA A+ C++ + SC
Sbjct: 370 TCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAK--SC 427
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWG------SXXXXXXXXXXXXXKGFAKLDGA 407
+ C+ + Q C ++ G S G+A G
Sbjct: 428 KNLIASYYCDCLPG--WMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYA---GD 482
Query: 408 TC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
C RD+DECA S GG C N ++C CP G +
Sbjct: 483 HCERDIDECA-SNPCLNGGHCQNEINRFQCLCPTGFS 518
Score = 60.1 bits (139), Expect = 2e-08
Identities = 80/332 (24%), Positives = 118/332 (35%), Gaps = 56/332 (16%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
D+C C +G C N P CE G L + G ++ C G + Y
Sbjct: 263 DKCIPHPGCVHGIC-NEPWQCLCETNWGGQLCDKDLNYCGTHQPC-LNGGTCSNTGPDKY 320
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDID 240
CPEG S N +I E + C + GSC+ G+ C C PG+ +ID
Sbjct: 321 QCSCPEGYSGPN--CEIAEHACLSDPCHNRGSCKETSLGFECECSPGW--TGPTCSTNID 376
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCP--------EGTRHEPELQLCRDIDECEGETETH 291
+C + C+ GG C++ F CVCP + +E E + C + C+ ++
Sbjct: 377 DCSPNN--CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASY 434
Query: 292 YIESDYERGDIPPTFPTR-TELASPCDN-GRCINTHGGFECECELGYVLDATAQRCLDNR 349
Y D G + + C N C + G+ C C GY D + +
Sbjct: 435 YC--DCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECA 492
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
C G C+ + R +C C G + G C
Sbjct: 493 SNPCLN---GGHCQNE----INRFQCLCPTGFS-----------------------GNLC 522
Query: 410 R-DVDECALSAELCAGGT-CVNTDGSYRCDCP 439
+ D+D C + C G C N Y C CP
Sbjct: 523 QLDIDYCEPNP--CQNGAQCYNRASDYFCKCP 552
>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 130 bits (313), Expect = 1e-29
Identities = 130/465 (27%), Positives = 194/465 (41%), Gaps = 64/465 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-CRDNPRVCR-RGRCRNTAGS 60
NGG C+N ++C C GY G C + C +P C RG C+ T+
Sbjct: 308 NGGTCSN----TGPDKYQCSCPEGYS----GPNCEIAEHACLSDP--CHNRGSCKETSLG 357
Query: 61 YTCLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC- 118
+ C C PG+ PT + ++D+C+ ++ GG C + F+CVC P T C
Sbjct: 358 FECECSPGWTGPTCS---TNIDDCSPNNCSHGGTCQDLVNGFKCVCP----PQWTGKTCQ 410
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPA 175
+D +ECE + C N S+ C+CLPG+ N + CLG + SC+
Sbjct: 411 LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLG-QCQNDASCRDL-V 468
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL 235
G Y +CP G + D+ DI+EC + P G C+N ++C+C G+ + L
Sbjct: 469 NG---YRCICPPGYAGDHCERDIDECASNP-CLNGGHCQNEINRFQCLCPTGF---SGNL 521
Query: 236 CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI-DECEGETETHYI 293
C+ DID C+ + G QC N A + C CPE + E + C + D C T I
Sbjct: 522 CQLDIDYCEPNPCQ-NGAQCYNRASDYFCKCPE----DYEGKNCSHLKDHCR-TTPCEVI 575
Query: 294 ES---DYERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGYV---LDATAQRC 345
+S D P R ++ C +G+C + GG F C+C G+ C
Sbjct: 576 DSCTVAMASNDTPE--GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC 633
Query: 346 LDN---RRGSCWRRVVDGQC------EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
N G+C V +C E A E + +C + G+
Sbjct: 634 ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-NDCSQNPCHNGGTCRDLVNDFYCD 692
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G+ G TC D A GGTC + +++C CP G
Sbjct: 693 CKNGW---KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Score = 121 bits (291), Expect = 6e-27
Identities = 124/464 (26%), Positives = 193/464 (41%), Gaps = 64/464 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNTAGSYTC 63
C N CKN+ + C C PG+ G C ++++C C+ CR+ Y C
Sbjct: 421 CVNAKSCKNLIASYYCDCLPGWM----GQNCDININDCLGQ---CQNDASCRDLVNGYRC 473
Query: 64 LCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PG+A +C D+DECA++ GG C N FQC+C G+ + +D+D
Sbjct: 474 ICPPGYA---GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ---LDID 527
Query: 123 ECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
C E C+NG +C+N + C+C + +G+ C LK C+ P + +
Sbjct: 528 YC-EPNPCQNGAQCYNRASDYFCKCPEDY----EGKNCSHLK----DHCRTTPCEVIDSC 578
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRD-I 239
V + + G I+ + V G PHG C++ G + C C+ G+ C + I
Sbjct: 579 TVAMASNDTPE-GVRYIS--SNVCG--PHGKCKSQSGGKFTCDCNKGF---TGTYCHENI 630
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETETHYIES- 295
++C+ + GG C + S+ C+C EG E + C G T +
Sbjct: 631 NDCESNPCR-NGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDF 689
Query: 296 --DYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGY----VLDATAQRCL 346
D + G T +R + C+N G C + F+C C G+ A CL
Sbjct: 690 YCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 347 DNRRGSCWRRVVDGQ-----CEAAAPELLLRQ---ECCCSVGLAWGSXXXXXXXXXXXXX 398
N + VV+G+ C+ + Q +C G+
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECA 809
Query: 399 KGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR +++EC S+ G TCV+ YRC CPPG
Sbjct: 810 PGFA---GPDCRININECQ-SSPCAFGATCVDEINGYRCVCPPG 849
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/230 (27%), Positives = 94/230 (40%), Gaps = 23/230 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ ++CIC G+E GA C ++++C NP C G CR+
Sbjct: 640 NGGTCIDGV-----NSYKCICSDGWE----GAYCETNINDCSQNP--CHNGGTCRDLVND 688
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACV 119
+ C C+ G+ C D ++ C GG C + +F+C+C G+ T A
Sbjct: 689 FYCDCKNGWKGKT---CHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA-- 743
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C G C SF C C G+ + + C G
Sbjct: 744 RNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTC-VDGDN 802
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY 228
Y C G + + +INEC + P C G+ C + GYRC+C PG+
Sbjct: 803 WYRCECAPGFAGPDCRININECQSSP--CAFGATCVDEINGYRCVCPPGH 850
Score = 73.3 bits (172), Expect = 2e-12
Identities = 71/278 (25%), Positives = 109/278 (39%), Gaps = 39/278 (14%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
C NG C+++ F C CK G++ G C D D G C + ++ C+C
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC 731
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
G+ T + C + GG CV + SF CVC+ G+ + ++C
Sbjct: 732 PGGWEGTTCNIARN-SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPI---CAQNTNDCS 787
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQ--------ACP 174
+G C + +RCEC PGF + + C +G +C CP
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 847
Query: 175 -----AQGSELYAVLCPEGPSKDNGGA----DINECTAVPGACPHGSCENLEPGYR-CIC 224
A+ E+ C S GA D N C + G +C + G R C+
Sbjct: 848 PGHSGAKCQEVSGRPCITMGSVIRDGAKWDDDCNTCQCLNGRI---ACSKVWCGPRPCLL 904
Query: 225 DPGYHPDADG-LCRDI--DECDMHQSYCAG-GQCRNTA 258
G+ G C I D+C +H C G G+CR+++
Sbjct: 905 HKGHSECPSGQSCIPILDDQCFVHP--CTGVGECRSSS 940
Score = 68.1 bits (159), Expect = 6e-11
Identities = 78/277 (28%), Positives = 112/277 (40%), Gaps = 45/277 (16%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQ 253
G ++C PG C HG C EP ++C+C+ + LC +D++ C HQ GG
Sbjct: 259 GLYCDKCIPHPG-CVHGICN--EP-WQCLCETNW---GGQLCDKDLNYCGTHQPCLNGGT 311
Query: 254 CRNTA-GSFTCVCPEG--------TRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C NT + C CPEG H C + C+ ET + E + G P
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK-ETSLGF-ECECSPGWTGP 369
Query: 305 TFPTRTELASP--CDN-GRCINTHGGFECECELGYV-----LDAT---AQRCLDNRRGSC 353
T T + SP C + G C + GF+C C + LDA A+ C++ + SC
Sbjct: 370 TCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAK--SC 427
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWG------SXXXXXXXXXXXXXKGFAKLDGA 407
+ C+ + Q C ++ G S G+A G
Sbjct: 428 KNLIASYYCDCLPG--WMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYA---GD 482
Query: 408 TC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
C RD+DECA S GG C N ++C CP G +
Sbjct: 483 HCERDIDECA-SNPCLNGGHCQNEINRFQCLCPTGFS 518
Score = 60.1 bits (139), Expect = 2e-08
Identities = 80/332 (24%), Positives = 118/332 (35%), Gaps = 56/332 (16%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
D+C C +G C N P CE G L + G ++ C G + Y
Sbjct: 263 DKCIPHPGCVHGIC-NEPWQCLCETNWGGQLCDKDLNYCGTHQPC-LNGGTCSNTGPDKY 320
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDID 240
CPEG S N +I E + C + GSC+ G+ C C PG+ +ID
Sbjct: 321 QCSCPEGYSGPN--CEIAEHACLSDPCHNRGSCKETSLGFECECSPGW--TGPTCSTNID 376
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCP--------EGTRHEPELQLCRDIDECEGETETH 291
+C + C+ GG C++ F CVCP + +E E + C + C+ ++
Sbjct: 377 DCSPNN--CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASY 434
Query: 292 YIESDYERGDIPPTFPTR-TELASPCDN-GRCINTHGGFECECELGYVLDATAQRCLDNR 349
Y D G + + C N C + G+ C C GY D + +
Sbjct: 435 YC--DCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECA 492
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
C G C+ + R +C C G + G C
Sbjct: 493 SNPCLN---GGHCQNE----INRFQCLCPTGFS-----------------------GNLC 522
Query: 410 R-DVDECALSAELCAGGT-CVNTDGSYRCDCP 439
+ D+D C + C G C N Y C CP
Sbjct: 523 QLDIDYCEPNP--CQNGAQCYNRASDYFCKCP 552
>AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 130 bits (313), Expect = 1e-29
Identities = 130/465 (27%), Positives = 194/465 (41%), Gaps = 64/465 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-CRDNPRVCR-RGRCRNTAGS 60
NGG C+N ++C C GY G C + C +P C RG C+ T+
Sbjct: 308 NGGTCSN----TGPDKYQCSCPEGYS----GPNCEIAEHACLSDP--CHNRGSCKETSLG 357
Query: 61 YTCLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC- 118
+ C C PG+ PT + ++D+C+ ++ GG C + F+CVC P T C
Sbjct: 358 FECECSPGWTGPTCS---TNIDDCSPNNCSHGGTCQDLVNGFKCVCP----PQWTGKTCQ 410
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPA 175
+D +ECE + C N S+ C+CLPG+ N + CLG + SC+
Sbjct: 411 LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLG-QCQNDASCRDL-V 468
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL 235
G Y +CP G + D+ DI+EC + P G C+N ++C+C G+ + L
Sbjct: 469 NG---YRCICPPGYAGDHCERDIDECASNP-CLNGGHCQNEINRFQCLCPTGF---SGNL 521
Query: 236 CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI-DECEGETETHYI 293
C+ DID C+ + G QC N A + C CPE + E + C + D C T I
Sbjct: 522 CQLDIDYCEPNPCQ-NGAQCYNRASDYFCKCPE----DYEGKNCSHLKDHCR-TTPCEVI 575
Query: 294 ES---DYERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGYV---LDATAQRC 345
+S D P R ++ C +G+C + GG F C+C G+ C
Sbjct: 576 DSCTVAMASNDTPE--GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC 633
Query: 346 LDN---RRGSCWRRVVDGQC------EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
N G+C V +C E A E + +C + G+
Sbjct: 634 ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-NDCSQNPCHNGGTCRDLVNDFYCD 692
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G+ G TC D A GGTC + +++C CP G
Sbjct: 693 CKNGW---KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Score = 121 bits (291), Expect = 6e-27
Identities = 124/464 (26%), Positives = 193/464 (41%), Gaps = 64/464 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNTAGSYTC 63
C N CKN+ + C C PG+ G C ++++C C+ CR+ Y C
Sbjct: 421 CVNAKSCKNLIASYYCDCLPGWM----GQNCDININDCLGQ---CQNDASCRDLVNGYRC 473
Query: 64 LCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PG+A +C D+DECA++ GG C N FQC+C G+ + +D+D
Sbjct: 474 ICPPGYA---GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ---LDID 527
Query: 123 ECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
C E C+NG +C+N + C+C + +G+ C LK C+ P + +
Sbjct: 528 YC-EPNPCQNGAQCYNRASDYFCKCPEDY----EGKNCSHLK----DHCRTTPCEVIDSC 578
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRD-I 239
V + + G I+ + V G PHG C++ G + C C+ G+ C + I
Sbjct: 579 TVAMASNDTPE-GVRYIS--SNVCG--PHGKCKSQSGGKFTCDCNKGF---TGTYCHENI 630
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETETHYIES- 295
++C+ + GG C + S+ C+C EG E + C G T +
Sbjct: 631 NDCESNPCR-NGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDF 689
Query: 296 --DYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGY----VLDATAQRCL 346
D + G T +R + C+N G C + F+C C G+ A CL
Sbjct: 690 YCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 347 DNRRGSCWRRVVDGQ-----CEAAAPELLLRQ---ECCCSVGLAWGSXXXXXXXXXXXXX 398
N + VV+G+ C+ + Q +C G+
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECA 809
Query: 399 KGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR +++EC S+ G TCV+ YRC CPPG
Sbjct: 810 PGFA---GPDCRININECQ-SSPCAFGATCVDEINGYRCVCPPG 849
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/230 (27%), Positives = 94/230 (40%), Gaps = 23/230 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ ++CIC G+E GA C ++++C NP C G CR+
Sbjct: 640 NGGTCIDGV-----NSYKCICSDGWE----GAYCETNINDCSQNP--CHNGGTCRDLVND 688
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACV 119
+ C C+ G+ C D ++ C GG C + +F+C+C G+ T A
Sbjct: 689 FYCDCKNGWKGKT---CHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA-- 743
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C G C SF C C G+ + + C G
Sbjct: 744 RNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTC-VDGDN 802
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY 228
Y C G + + +INEC + P C G+ C + GYRC+C PG+
Sbjct: 803 WYRCECAPGFAGPDCRININECQSSP--CAFGATCVDEINGYRCVCPPGH 850
Score = 73.7 bits (173), Expect = 1e-12
Identities = 71/281 (25%), Positives = 110/281 (39%), Gaps = 45/281 (16%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
C NG C+++ F C CK G++ G C D D G C + ++ C+C
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC 731
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
G+ T + C + GG CV + SF CVC+ G+ + ++C
Sbjct: 732 PGGWEGTTCNIARN-SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPI---CAQNTNDCS 787
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFT------LSND--------GRTCLGLKLGW----- 166
+G C + +RCEC PGF N+ G TC+ G+
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 847
Query: 167 ----GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR- 221
G CQ + + P+G D+ D N C + G +C + G R
Sbjct: 848 PGHSGAKCQEVSGRPCITMGSVIPDGAKWDD---DCNTCQCLNGRI---ACSKVWCGPRP 901
Query: 222 CICDPGYHPDADG-LCRDI--DECDMHQSYCAG-GQCRNTA 258
C+ G+ G C I D+C +H C G G+CR+++
Sbjct: 902 CLLHKGHSECPSGQSCIPILDDQCFVHP--CTGVGECRSSS 940
Score = 68.1 bits (159), Expect = 6e-11
Identities = 78/277 (28%), Positives = 112/277 (40%), Gaps = 45/277 (16%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQ 253
G ++C PG C HG C EP ++C+C+ + LC +D++ C HQ GG
Sbjct: 259 GLYCDKCIPHPG-CVHGICN--EP-WQCLCETNW---GGQLCDKDLNYCGTHQPCLNGGT 311
Query: 254 CRNTA-GSFTCVCPEG--------TRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C NT + C CPEG H C + C+ ET + E + G P
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK-ETSLGF-ECECSPGWTGP 369
Query: 305 TFPTRTELASP--CDN-GRCINTHGGFECECELGYV-----LDAT---AQRCLDNRRGSC 353
T T + SP C + G C + GF+C C + LDA A+ C++ + SC
Sbjct: 370 TCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAK--SC 427
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWG------SXXXXXXXXXXXXXKGFAKLDGA 407
+ C+ + Q C ++ G S G+A G
Sbjct: 428 KNLIASYYCDCLPG--WMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYA---GD 482
Query: 408 TC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
C RD+DECA S GG C N ++C CP G +
Sbjct: 483 HCERDIDECA-SNPCLNGGHCQNEINRFQCLCPTGFS 518
Score = 60.1 bits (139), Expect = 2e-08
Identities = 80/332 (24%), Positives = 118/332 (35%), Gaps = 56/332 (16%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
D+C C +G C N P CE G L + G ++ C G + Y
Sbjct: 263 DKCIPHPGCVHGIC-NEPWQCLCETNWGGQLCDKDLNYCGTHQPC-LNGGTCSNTGPDKY 320
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDID 240
CPEG S N +I E + C + GSC+ G+ C C PG+ +ID
Sbjct: 321 QCSCPEGYSGPN--CEIAEHACLSDPCHNRGSCKETSLGFECECSPGW--TGPTCSTNID 376
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCP--------EGTRHEPELQLCRDIDECEGETETH 291
+C + C+ GG C++ F CVCP + +E E + C + C+ ++
Sbjct: 377 DCSPNN--CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASY 434
Query: 292 YIESDYERGDIPPTFPTR-TELASPCDN-GRCINTHGGFECECELGYVLDATAQRCLDNR 349
Y D G + + C N C + G+ C C GY D + +
Sbjct: 435 YC--DCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECA 492
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
C G C+ + R +C C G + G C
Sbjct: 493 SNPCLN---GGHCQNE----INRFQCLCPTGFS-----------------------GNLC 522
Query: 410 R-DVDECALSAELCAGGT-CVNTDGSYRCDCP 439
+ D+D C + C G C N Y C CP
Sbjct: 523 QLDIDYCEPNP--CQNGAQCYNRASDYFCKCP 552
>AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 130 bits (313), Expect = 1e-29
Identities = 137/469 (29%), Positives = 185/469 (39%), Gaps = 72/469 (15%)
Query: 4 GGMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
G C N CKN+ GG+ C C PG++ G C +V++CR C+ G C++
Sbjct: 429 GKPCLNAFSCKNLIGGYYCDCIPGWK----GINCHINVNDCRGQ---CQHGGTCKDLVNG 481
Query: 61 YTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
Y C+C GF +C + DECA+ GG C + F C C G+ V
Sbjct: 482 YQCVCPRGFG---GRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---V 535
Query: 120 DVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
DVD CE CRNG RC+N G + C C F G+ C V + CP
Sbjct: 536 DVDLCEPSP-CRNGARCYNLEGDYYCACPDDF----GGKNC-------SVPREPCPGGAC 583
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPG--YRCICDPGYHPDADGL 235
+ +G D G TA G C PHG C + +PG + CICD G+
Sbjct: 584 RVI-----DGCGSDAGPG--MPGTAASGVCGPHGRCVS-QPGGNFSCICDSGF---TGTY 632
Query: 236 CRD-IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI--DECEGETETHY 292
C + ID+C + Q GG C + +F C CP G E D D C +
Sbjct: 633 CHENIDDC-LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYD 691
Query: 293 IESDY----ERGDIPPTFPTRTEL--ASPCDN-GRCINTHGGFECECELGYVLDATA--- 342
+ +D+ + G T +R A C N G C ++ F C C G+ A
Sbjct: 692 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 343 -QRCLDN---RRGSCWRRVVDGQC---EAAAPELLLRQECCCSVGLAW--GSXXXXXXXX 393
CL N G+C C + C+ + G
Sbjct: 752 NSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 811
Query: 394 XXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR ++DEC S+ G TCV+ YRC CPPG
Sbjct: 812 RCECAPGFA---GPDCRINIDECQ-SSPCAYGATCVDEINGYRCSCPPG 856
Score = 127 bits (307), Expect = 7e-29
Identities = 129/461 (27%), Positives = 190/461 (41%), Gaps = 62/461 (13%)
Query: 7 CTNG-ICKNIDGG-FECICKPGYESGSEGALCRDVDE-CRDNPRVCRRGRCRNTAGSYTC 63
CTNG C N + + C C GY G C + C NP G C + C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYS----GRNCEKAEHACTSNP-CANGGSCHEVPSGFEC 371
Query: 64 LCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C G++ PT A D+DECA++ GG CV+ F+C+C + + +D +
Sbjct: 372 HCPSGWSGPTCA---LDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQ---LDAN 425
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGSE 179
ECE + C N G + C+C+PG+ N + C G + G +C+ G
Sbjct: 426 ECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRG-QCQHGGTCKDL-VNG-- 481
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
Y +CP G + + +EC + P C G CE+L G+ C C G+ + LC
Sbjct: 482 -YQCVCPRGFGGRHCELERDECASSP--CHSGGLCEDLADGFHCHCPQGF---SGPLCEV 535
Query: 238 DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
D+D C+ S C G +C N G + C CP+ + + R + C G I D
Sbjct: 536 DVDLCE--PSPCRNGARCYNLEGDYYCACPDDFGGK-NCSVPR--EPCPGGA-CRVI--D 587
Query: 297 YERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGY--------VLDATAQRCL 346
D P P T + C +GRC++ GG F C C+ G+ + D Q C
Sbjct: 588 GCGSDAGPGMP-GTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCR 646
Query: 347 DNRRGSCWRRVVDGQCEAAA---PEL--LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
+ G+C V +C + EL +C + G G+
Sbjct: 647 NG--GTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 704
Query: 402 AKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
G TC E A C+ GGTC ++ ++RC CPPG
Sbjct: 705 ---KGKTCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPG 741
Score = 112 bits (270), Expect = 2e-24
Identities = 133/473 (28%), Positives = 179/473 (37%), Gaps = 68/473 (14%)
Query: 6 MCTNGICKNIDGGF----ECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
+C G C + GG EC C G++ G C DEC P C G C +
Sbjct: 244 VCKQG-CNLLHGGCTVPGECRCSYGWQ----GRFC---DECVPYPG-CVHGSC---VEPW 291
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMC-KGGRCVNSE-GSFQCVCEAGYRPTATRGACV 119
C CE + D++ C + C GG C+N+E ++C C GY + C
Sbjct: 292 QCNCETNWGGLLCD--KDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNCE 345
Query: 120 DVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+ C NG CH P F C C G++ G TC L + S C A G+
Sbjct: 346 KAEHACTSNPCANGGSCHEVPSGFECHCPSGWS----GPTC-ALDIDECAS-NPCAAGGT 399
Query: 179 -----ELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDA 232
+ + +CPE D NEC P C + SC+NL GY C C PG+
Sbjct: 400 CVDQVDGFECICPEQWVGATCQLDANECEGKP--CLNAFSCKNLIGGYYCDCIPGWK--- 454
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT--RH-EPELQLCRDIDECEG--- 286
G+ I+ D GG C++ + CVCP G RH E E C G
Sbjct: 455 -GINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLC 513
Query: 287 ETETHYIESDYERGDIPPTFPTRTELA--SPCDNG-RCINTHGGFECECELGYVLDATAQ 343
E +G P +L SPC NG RC N G + C C D +
Sbjct: 514 EDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPD----DFGGK 569
Query: 344 RCLDNRR----GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK 399
C R G+C RV+DG C + A + G
Sbjct: 570 NCSVPREPCPGGAC--RVIDG-CGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDS 626
Query: 400 GFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
GF G C + +D+C L GGTC++ ++RC CP G + T P
Sbjct: 627 GFT---GTYCHENIDDC-LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNP 675
Score = 100 bits (240), Expect = 9e-21
Identities = 106/392 (27%), Positives = 163/392 (41%), Gaps = 70/392 (17%)
Query: 5 GMC-TNGICKNIDGG-FECICKPGYESGSEGALCRD-VDECRDNPRVCRRG-RCRNTAGS 60
G+C +G C + GG F CIC +SG G C + +D+C P CR G C + +
Sbjct: 604 GVCGPHGRCVSQPGGNFSCIC----DSGFTGTYCHENIDDCLGQP--CRNGGTCIDEVDA 657
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C C G+ + ++C D GRC + F C C+ G++
Sbjct: 658 FRCFCPSGWEGELCD--TNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR--- 712
Query: 121 VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-----GVSCQACPA 175
+C+ G C+++ +FRC C PG+ G TC K V+ C
Sbjct: 713 EFQCDAYTCSNGGTCYDSGDTFRCACPPGW----KGSTCAVAKNSSCLPNPCVNGGTCVG 768
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY-HPDAD 233
G+ ++ +C +G + N+C +P C +G C + +RC C PG+ PD
Sbjct: 769 SGAS-FSCICRDGWEGRTCTHNTNDCNPLP--CYNGGICVDGVNWFRCECAPGFAGPD-- 823
Query: 234 GLCR-DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
CR +IDEC S CA G C + + C CP G R P C+++
Sbjct: 824 --CRINIDEC--QSSPCAYGATCVDEINGYRCSCPPG-RAGPR---CQEV--------IG 867
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE--------CELGYVLDATA- 342
+ S + RG FP + C++ RC++ G +C C L +A +
Sbjct: 868 FGRSCWSRG---TPFPHGSSWVEDCNSCRCLD--GRRDCSKVWCGWKPCLLAGQPEALSA 922
Query: 343 -----QRCLDNRRGSCWRRVVD--GQCEAAAP 367
QRCL+ G C R + G+C A P
Sbjct: 923 QCPLGQRCLEKAPGQCLRPPCEAWGECGAEEP 954
>AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein
Jagged 1 protein.
Length = 1218
Score = 130 bits (313), Expect = 1e-29
Identities = 130/465 (27%), Positives = 194/465 (41%), Gaps = 64/465 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDE-CRDNPRVCR-RGRCRNTAGS 60
NGG C+N ++C C GY G C + C +P C RG C+ T+
Sbjct: 308 NGGTCSN----TGPDKYQCSCPEGYS----GPNCEIAEHACLSDP--CHNRGSCKETSLG 357
Query: 61 YTCLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC- 118
+ C C PG+ PT + ++D+C+ ++ GG C + F+CVC P T C
Sbjct: 358 FECECSPGWTGPTCS---TNIDDCSPNNCSHGGTCQDLVNGFKCVCP----PQWTGKTCQ 410
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPA 175
+D +ECE + C N S+ C+CLPG+ N + CLG + SC+
Sbjct: 411 LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLG-QCQNDASCRDL-V 468
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL 235
G Y +CP G + D+ DI+EC + P G C+N ++C+C G+ + L
Sbjct: 469 NG---YRCICPPGYAGDHCERDIDECASNP-CLNGGHCQNEINRFQCLCPTGF---SGNL 521
Query: 236 CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI-DECEGETETHYI 293
C+ DID C+ + G QC N A + C CPE + E + C + D C T I
Sbjct: 522 CQLDIDYCEPNPCQ-NGAQCYNRASDYFCKCPE----DYEGKNCSHLKDHCR-TTPCEVI 575
Query: 294 ES---DYERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGYV---LDATAQRC 345
+S D P R ++ C +G+C + GG F C+C G+ C
Sbjct: 576 DSCTVAMASNDTPE--GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC 633
Query: 346 LDN---RRGSCWRRVVDGQC------EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
N G+C V +C E A E + +C + G+
Sbjct: 634 ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-NDCSQNPCHNGGTCRDLVNDFYCD 692
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G+ G TC D A GGTC + +++C CP G
Sbjct: 693 CKNGW---KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Score = 121 bits (291), Expect = 6e-27
Identities = 124/464 (26%), Positives = 193/464 (41%), Gaps = 64/464 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNTAGSYTC 63
C N CKN+ + C C PG+ G C ++++C C+ CR+ Y C
Sbjct: 421 CVNAKSCKNLIASYYCDCLPGWM----GQNCDININDCLGQ---CQNDASCRDLVNGYRC 473
Query: 64 LCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
+C PG+A +C D+DECA++ GG C N FQC+C G+ + +D+D
Sbjct: 474 ICPPGYA---GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ---LDID 527
Query: 123 ECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
C E C+NG +C+N + C+C + +G+ C LK C+ P + +
Sbjct: 528 YC-EPNPCQNGAQCYNRASDYFCKCPEDY----EGKNCSHLK----DHCRTTPCEVIDSC 578
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRD-I 239
V + + G I+ + V G PHG C++ G + C C+ G+ C + I
Sbjct: 579 TVAMASNDTPE-GVRYIS--SNVCG--PHGKCKSQSGGKFTCDCNKGF---TGTYCHENI 630
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECEGETETHYIES- 295
++C+ + GG C + S+ C+C EG E + C G T +
Sbjct: 631 NDCESNPCR-NGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDF 689
Query: 296 --DYERGDIPPTFPTRTELA--SPCDN-GRCINTHGGFECECELGY----VLDATAQRCL 346
D + G T +R + C+N G C + F+C C G+ A CL
Sbjct: 690 YCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 347 DNRRGSCWRRVVDGQ-----CEAAAPELLLRQ---ECCCSVGLAWGSXXXXXXXXXXXXX 398
N + VV+G+ C+ + Q +C G+
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECA 809
Query: 399 KGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR +++EC S+ G TCV+ YRC CPPG
Sbjct: 810 PGFA---GPDCRININECQ-SSPCAFGATCVDEINGYRCVCPPG 849
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/230 (27%), Positives = 94/230 (40%), Gaps = 23/230 (10%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C +G+ ++CIC G+E GA C ++++C NP C G CR+
Sbjct: 640 NGGTCIDGV-----NSYKCICSDGWE----GAYCETNINDCSQNP--CHNGGTCRDLVND 688
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACV 119
+ C C+ G+ C D ++ C GG C + +F+C+C G+ T A
Sbjct: 689 FYCDCKNGWKGKT---CHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA-- 743
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
C G C SF C C G+ + + C G
Sbjct: 744 RNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTC-VDGDN 802
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY 228
Y C G + + +INEC + P C G+ C + GYRC+C PG+
Sbjct: 803 WYRCECAPGFAGPDCRININECQSSP--CAFGATCVDEINGYRCVCPPGH 850
Score = 73.7 bits (173), Expect = 1e-12
Identities = 71/281 (25%), Positives = 110/281 (39%), Gaps = 45/281 (16%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
C NG C+++ F C CK G++ G C D D G C + ++ C+C
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWK----GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC 731
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
G+ T + C + GG CV + SF CVC+ G+ + ++C
Sbjct: 732 PGGWEGTTCNIARN-SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPI---CAQNTNDCS 787
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFT------LSND--------GRTCLGLKLGW----- 166
+G C + +RCEC PGF N+ G TC+ G+
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 847
Query: 167 ----GVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR- 221
G CQ + + P+G D+ D N C + G +C + G R
Sbjct: 848 PGHSGAKCQEVSGRPCITMGSVIPDGAKWDD---DCNTCQCLNGRI---ACSKVWCGPRP 901
Query: 222 CICDPGYHPDADG-LCRDI--DECDMHQSYCAG-GQCRNTA 258
C+ G+ G C I D+C +H C G G+CR+++
Sbjct: 902 CLLHKGHSECPSGQSCIPILDDQCFVHP--CTGVGECRSSS 940
Score = 68.1 bits (159), Expect = 6e-11
Identities = 78/277 (28%), Positives = 112/277 (40%), Gaps = 45/277 (16%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQ 253
G ++C PG C HG C EP ++C+C+ + LC +D++ C HQ GG
Sbjct: 259 GLYCDKCIPHPG-CVHGICN--EP-WQCLCETNW---GGQLCDKDLNYCGTHQPCLNGGT 311
Query: 254 CRNTA-GSFTCVCPEG--------TRHEPELQLCRDIDECEGETETHYIESDYERGDIPP 304
C NT + C CPEG H C + C+ ET + E + G P
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK-ETSLGF-ECECSPGWTGP 369
Query: 305 TFPTRTELASP--CDN-GRCINTHGGFECECELGYV-----LDAT---AQRCLDNRRGSC 353
T T + SP C + G C + GF+C C + LDA A+ C++ + SC
Sbjct: 370 TCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAK--SC 427
Query: 354 WRRVVDGQCEAAAPELLLRQECCCSVGLAWG------SXXXXXXXXXXXXXKGFAKLDGA 407
+ C+ + Q C ++ G S G+A G
Sbjct: 428 KNLIASYYCDCLPG--WMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYA---GD 482
Query: 408 TC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
C RD+DECA S GG C N ++C CP G +
Sbjct: 483 HCERDIDECA-SNPCLNGGHCQNEINRFQCLCPTGFS 518
Score = 60.1 bits (139), Expect = 2e-08
Identities = 80/332 (24%), Positives = 118/332 (35%), Gaps = 56/332 (16%)
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY 181
D+C C +G C N P CE G L + G ++ C G + Y
Sbjct: 263 DKCIPHPGCVHGIC-NEPWQCLCETNWGGQLCDKDLNYCGTHQPC-LNGGTCSNTGPDKY 320
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDID 240
CPEG S N +I E + C + GSC+ G+ C C PG+ +ID
Sbjct: 321 QCSCPEGYSGPN--CEIAEHACLSDPCHNRGSCKETSLGFECECSPGW--TGPTCSTNID 376
Query: 241 ECDMHQSYCA-GGQCRNTAGSFTCVCP--------EGTRHEPELQLCRDIDECEGETETH 291
+C + C+ GG C++ F CVCP + +E E + C + C+ ++
Sbjct: 377 DCSPNN--CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASY 434
Query: 292 YIESDYERGDIPPTFPTR-TELASPCDN-GRCINTHGGFECECELGYVLDATAQRCLDNR 349
Y D G + + C N C + G+ C C GY D + +
Sbjct: 435 YC--DCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECA 492
Query: 350 RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC 409
C G C+ + R +C C G + G C
Sbjct: 493 SNPCLN---GGHCQNE----INRFQCLCPTGFS-----------------------GNLC 522
Query: 410 R-DVDECALSAELCAGGT-CVNTDGSYRCDCP 439
+ D+D C + C G C N Y C CP
Sbjct: 523 QLDIDYCEPNP--CQNGAQCYNRASDYFCKCP 552
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 128 bits (309), Expect = 4e-29
Identities = 135/476 (28%), Positives = 186/476 (39%), Gaps = 75/476 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRG-RCRNTAGS 60
NGG C +G+ + C+C E+ + DVDEC P CR G C+N+AGS
Sbjct: 287 NGGTCQDGL-----DTYTCLCP---ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C+C G+ T+ ++D+C A + G C++ GSF C+C G T C
Sbjct: 339 FHCVCVSGWGGTSCE--ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGLLCHL 392
Query: 121 VDECEEQRVCRNGRCHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLG-----WGVSC 170
D C Q + +C P GS C C PG+ T D CL + G G SC
Sbjct: 393 EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 452
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
P GS + LCP G + AD NEC + P P +C +L + C+C PG
Sbjct: 453 LNTP--GS--FNCLCPPGYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGLEG 507
Query: 231 DADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEG 286
LC +++ + + C C + F C+C P GTR E ++ CR G
Sbjct: 508 Q---LC-EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANG 563
Query: 287 ---ETETHYIESDYERGDIPPTFPTRTE--LASPCDNGR-CINTHGGFECECELGYV--- 337
+ + G P T + L+ PC G C++ G F C C G+
Sbjct: 564 GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQL 623
Query: 338 ---------LDATAQRCLDNR-RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
L Q C D + + +C DG A PE C C G S
Sbjct: 624 CEVPLCAPNLCQPKQICKDQKDKANCL--CPDGSPGCAPPE----DNCTCHHGHCQRSSC 677
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ G C +SA GGTC Y C CP G T
Sbjct: 678 VCDV--------GWT---GPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 722
Score = 120 bits (289), Expect = 1e-26
Identities = 115/419 (27%), Positives = 155/419 (36%), Gaps = 71/419 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
G C N G F C+C PGY G+ C D +EC P C G C + ++ CLC P
Sbjct: 450 GSCLNTPGSFNCLCPPGYT----GSRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPP 503
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
G + +ECA+ C + FQC+C G+ T D+DEC
Sbjct: 504 GLEGQLCE--VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE---DIDECRSS 558
Query: 128 RVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
G+C + PG+F C+CLPGF + CL G SC P + L
Sbjct: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA----FFCL 614
Query: 185 CPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCIC---DPGYHPDAD------G 234
CP G + ++ C P C P C++ + C+C PG P D G
Sbjct: 615 CPSGFTGQL--CEVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHG 670
Query: 235 LCR------DID----ECDMHQSYCA------GGQCRNTAGSFTCVCPEGTRH---EPEL 275
C+ D+ EC+ C GG C + C CP G E+
Sbjct: 671 HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
Query: 276 QLCRDIDECEGETETHYIESDYERGDIP----PTFPTRTE--LASPCDNG-RCINTHGGF 328
C C + Y P P T T+ +++PC NG C+N G F
Sbjct: 731 TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTF 789
Query: 329 ECECELGYVLDATAQRCLDNRRGSCWRRVVDGQC--EAAAPELLLRQECCCSVGLAWGS 385
C C +G+ RC R SC D C A + C C G GS
Sbjct: 790 SCLCAMGF----QGPRCEGKLRPSC----ADSPCRNRATCQDSPQGPRCLCPTGYTGGS 840
Score = 119 bits (287), Expect = 2e-26
Identities = 130/465 (27%), Positives = 183/465 (39%), Gaps = 62/465 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRR-GRCRNT--AGSYT 62
C G C + G F C+C PG G LC D C P C +C GS
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPG----RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTL 417
Query: 63 CLCEPGFA-PTAAGYCADVDECA----ADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRG 116
CLC+PG++ PT D+DEC S C+ GG C+N+ GSF C+C GY T +R
Sbjct: 418 CLCQPGYSGPTCH---QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSR- 471
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP-- 174
D +EC Q C + +F C C PG +G+ C ++ C + P
Sbjct: 472 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGL----EGQLC-EVETN---ECASAPCL 523
Query: 175 --AQGSEL---YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A +L + +C G S DI+EC + P A G C++ + C C PG+
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCA-NGGQCQDQPGAFHCKCLPGF- 581
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPEL-----QLCRDIDE 283
+ ++DEC + G C + G+F C+CP G T E+ LC+
Sbjct: 582 -EGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQI 639
Query: 284 CEGETE-THYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG--GFECECELGYVLDA 340
C+ + + + + D G PP T C C+ G G ECE ELG + A
Sbjct: 640 CKDQKDKANCLCPDGSPGCAPPE-DNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISA 698
Query: 341 TAQRCLDNRRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
C G+C+ + C P C S G
Sbjct: 699 P---CAHG--GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C+ + +SA GGTCVN G++ C C G
Sbjct: 754 TCP--PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
Score = 117 bits (281), Expect = 1e-25
Identities = 126/440 (28%), Positives = 174/440 (39%), Gaps = 51/440 (11%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCR-NTAGSYTCLCEPGFAPTAAGY 76
F C C PG+ E + D C P C +RGRC +G C C PG+
Sbjct: 101 FLCTCLPGFTG--ERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT---GEQ 153
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNG-R 134
C D C+A+ GG C+ + QC C G+ A DV+EC ++ C G
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS 210
Query: 135 CHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
CHNT GSF+C C G C G +CQ P + S + LCP P
Sbjct: 211 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP--PGF 268
Query: 192 DNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH-QSYC 249
++N V C + G+C++ Y C+C P D D+DEC+ +C
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC-PETWTGWD-CSEDVDECETQGPPHC 326
Query: 250 A-GGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
GG C+N+AGSF CVC GT E L C G T I+ + P
Sbjct: 327 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGST---CIDRVGSFSCLCP- 382
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
P RT L ++ C++ + +C + +T C G C
Sbjct: 383 -PGRTGLLCHLED-MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP--------TCHQD 432
Query: 366 APELLLRQE--CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELC 422
E L+ Q+ C G GS G+ G+ C D +EC LS
Sbjct: 433 LDECLMAQQGPSPCEHG---GSCLNTPGSFNCLCPPGYT---GSRCEADHNEC-LSQPCH 485
Query: 423 AGGTCVNTDGSYRCDCPPGL 442
G TC++ ++ C CPPGL
Sbjct: 486 PGSTCLDLLATFHCLCPPGL 505
Score = 111 bits (267), Expect = 5e-24
Identities = 104/354 (29%), Positives = 140/354 (39%), Gaps = 42/354 (11%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS 60
+ G C NG C GG+ C C P + G C+ D C P G C N G+
Sbjct: 734 HSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTDYCVSAP-CFNGGTCVNRPGT 788
Query: 61 YTCLCEPGF-APTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGAC 118
++CLC GF P G + ADS C+ C +S +C+C GY T G+C
Sbjct: 789 FSCLCAMGFQGPRCEG---KLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TGGSC 841
Query: 119 VD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSN-DGRTCLGLKLGWGVSCQACP 174
+D C ++ RN C T SF C CL G+T L N +C L G+ +
Sbjct: 842 QTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 901
Query: 175 AQG------SELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPG 227
G Y CP G +N C + P C +G +C GY C C PG
Sbjct: 902 HNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPG 959
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDEC 284
Y D +++D C + G C G F C CP G R E ++ C D C
Sbjct: 960 Y--DGQNCSKELDACQSQPCH-NHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD-QPC 1015
Query: 285 E--GETETHYIESDYERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELG 335
G H + + + +P E+ PC + C HGG CE G
Sbjct: 1016 HPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCF--HGG-TCEATAG 1066
Score = 110 bits (265), Expect = 9e-24
Identities = 119/470 (25%), Positives = 177/470 (37%), Gaps = 78/470 (16%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C ++ GF+CIC PG+ G C D+DECR +P G+C++ G++ C C PGF
Sbjct: 528 CHDLLNGFQCICLPGFS----GTRCEEDIDECRSSP-CANGGQCQDQPGAFHCKCLPGFE 582
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR------PTATRGACVDVDEC 124
+VDEC +D G C++ G+F C+C +G+ P C C
Sbjct: 583 GPRCQ--TEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 640
Query: 125 EEQR-----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-GVSCQA------ 172
++Q+ +C +G P C C G + +C+ +GW G C+A
Sbjct: 641 KDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS---SCV-CDVGWTGPECEAELGGCI 696
Query: 173 ---CPAQGS-----ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
C G+ Y CP G + ++ C + P GSC GY C C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP-CLNGGSCNPSPGGYYCTC 755
Query: 225 DPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQL---- 277
P + C+ + + GG C N G+F+C+C +G R E +L+
Sbjct: 756 PPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 812
Query: 278 --CRDIDECEGETETH--YIESDYERGDIPPTFPTRTELASPCD-NGRCINTHGGFECEC 332
CR+ C+ + + Y G + PC N C+ T F C C
Sbjct: 813 SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQ--KPCPRNSHCLQTGPSFHCLC 870
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
G+ T C + C+ AA + C G G
Sbjct: 871 LQGW----TGPLC----------NLPLSSCQKAALSQGIDVSSLCHNG---GLCVDSGPS 913
Query: 393 XXXXXXKGFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G+ C+D V+ C S G TC+ Y C C PG
Sbjct: 914 YFCHCPPGF---QGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQCAPG 959
Score = 110 bits (264), Expect = 1e-23
Identities = 138/473 (29%), Positives = 189/473 (39%), Gaps = 89/473 (18%)
Query: 5 GMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCR----NT 57
G C G C N G F+C+C G EG C C PR C G C+
Sbjct: 203 GPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCP--PRGCSNGGTCQLMPEKD 256
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ + CLC PGF + D C + GG C + ++ C+C T T
Sbjct: 257 STFHLCLCPPGFIGPDCE--VNPDNCVSHQCQNGGTCQDGLDTYTCLCPE----TWTGWD 310
Query: 118 CV-DVDECEEQRV--CRNG-RCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSC 170
C DVDECE Q CRNG C N+ GSF C C+ G+ + + C+ G +C
Sbjct: 311 CSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG----SCENLEPGYRCICDP 226
GS ++ LCP G + + + C + P C HG S L C+C P
Sbjct: 371 --IDRVGS--FSCLCPPGRTGLLCHLE-DMCLSQP--C-HGDAQCSTNPLTGSTLCLCQP 422
Query: 227 GYHPDADGLC-RDIDECDMHQ---SYCA-GGQCRNTAGSFTCVCP---EGTRHEPE---- 274
GY + C +D+DEC M Q S C GG C NT GSF C+CP G+R E +
Sbjct: 423 GY---SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 479
Query: 275 -LQLCRDIDECEGETET-HYIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECE 331
Q C C T H + G + T ++PC ++ C + GF+C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV-ETNECASAPCLNHADCHDLLNGFQCI 538
Query: 332 CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
C G+ + +D R S GQC+ C C G
Sbjct: 539 CLPGF-SGTRCEEDIDECRSSPCAN--GGQCQDQPGAF----HCKCLPG----------- 580
Query: 392 XXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G C+ +VDEC LS G +C++ G++ C CP G T
Sbjct: 581 ------------FEGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFT 620
Score = 96.7 bits (230), Expect = 1e-19
Identities = 119/461 (25%), Positives = 169/461 (36%), Gaps = 71/461 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTC 63
C NG +C +C C PG+ EG C RDV+EC +P C +G C NT GS+ C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 220
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRC---VNSEGSFQ-CVCEAGYRPTATRGACV 119
LC G A C GG C + +F C+C G+ V
Sbjct: 221 LCPVGQEGPRCELRA--GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---V 275
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ D C + G C + ++ C C G+ S D C + C
Sbjct: 276 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ V C G + ++++C A A P +C + + C+C PG GL
Sbjct: 336 AGSFHCV-CVSGWGGTSCEENLDDCIAATCA-PGSTCIDRVGSFSCLCPPG----RTGLL 389
Query: 237 RDIDECDMHQSYCAGGQCRNT--AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
+++ + Q QC GS C+C G P +D+DEC
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPG-YSGPTCH--QDLDEC---------- 436
Query: 295 SDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLDN-- 348
++G SPC++ G C+NT G F C C GY +A CL
Sbjct: 437 LMAQQG------------PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPC 484
Query: 349 RRGS-CWRRVVDGQCEAAAPEL------LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GS C + C P L + EC + L GF
Sbjct: 485 HPGSTCLDLLATFHC-LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ G C D+DEC S+ GG C + G++ C C PG
Sbjct: 544 S---GTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKCLPG 580
Score = 90.6 bits (215), Expect = 1e-17
Identities = 127/462 (27%), Positives = 171/462 (37%), Gaps = 81/462 (17%)
Query: 42 CRDNPRVCRRG-RCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCV--- 95
C P C G C + + G TC C PGF C D C +C+ GG C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQALL 84
Query: 96 -------NSEG----SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH-NTPGSFR 143
+S SF C C G+ T R D C + GRCH G +
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 142
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--YAVL---CPEGPSKDNGGADI 198
C C+PG+T G C +L S C G L Y + CP G D+
Sbjct: 143 CSCMPGWT----GEQC---QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 195
Query: 199 NECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCR- 255
NEC PG CP G SC N ++C+C G +G ++ C+ GG C+
Sbjct: 196 NECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQL 251
Query: 256 ---NTAGSFTCVCPEG-----TRHEPE---LQLCRDIDECEG--ETETHYIESDYERGDI 302
+ C+CP G P+ C++ C+ +T T + D
Sbjct: 252 MPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 311
Query: 303 PPTF-PTRTELASPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGS 352
T+ C N G C N+ G F C C G+ + D A C +
Sbjct: 312 SEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG--ST 369
Query: 353 CWRRV--VDGQCEAAAPELLLRQECCC----SVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
C RV C LL E C G A S G++ G
Sbjct: 370 CIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS---G 426
Query: 407 ATC-RDVDECALSAE---LCA-GGTCVNTDGSYRCDCPPGLT 443
TC +D+DEC ++ + C GG+C+NT GS+ C CPPG T
Sbjct: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
Score = 88.6 bits (210), Expect = 4e-17
Identities = 90/353 (25%), Positives = 130/353 (36%), Gaps = 59/353 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C G+ C C GY G C ++ C P + G C + G Y C C P
Sbjct: 704 GTCYPQPSGYNCTCPTGYT----GPTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPS 758
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
T D C + GG CVN G+F C+C G++ G C +
Sbjct: 759 H--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--RPSCADS- 813
Query: 129 VCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
CRN C ++P RC C G+T +T + L + Q + LC +
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 872
Query: 188 G--------PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRD 238
G P A +++ V C +G C + P Y C C PG+ LC+D
Sbjct: 873 GWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ---GSLCQD 929
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
H + C C+N A TC+ +P LC+ +G+ + +++
Sbjct: 930 ------HVNPCESRPCQNGA---TCMA------QPSGYLCQCAPGYDGQNCSKELDACQ- 973
Query: 299 RGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLD 347
+ PC N G C GGF C C G+V + CLD
Sbjct: 974 --------------SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD 1012
Score = 73.3 bits (172), Expect = 2e-12
Identities = 70/264 (26%), Positives = 97/264 (36%), Gaps = 35/264 (13%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECR--------DNPRVCRRGR-CRNTA 58
N C F C+C G+ G LC + C+ D +C G C ++
Sbjct: 856 NSHCLQTGPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSG 911
Query: 59 GSYTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
SY C C PGF C D V+ C + G C+ + C C GY +
Sbjct: 912 PSYFCHCPPGFQ---GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDG---QNC 965
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACP 174
++D C+ Q +G C PG F C C PGF D CL AC
Sbjct: 966 SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPC-HPTGTAACH 1024
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENL--EP-GYRCICDPGYHP 230
+ + Y C G + +I+ C + P C H G+CE P G+ C C G+
Sbjct: 1025 SLANAFYC-QCLPGHTGQWCEVEIDPCHSQP--CFHGGTCEATAGSPLGFICHCPKGF-- 1079
Query: 231 DADGLCRDIDECDMHQSYCAGGQC 254
+ C H + GG C
Sbjct: 1080 EGPTCSHRAPSCGFHHCH-HGGLC 1102
Score = 62.5 bits (145), Expect = 3e-09
Identities = 78/270 (28%), Positives = 97/270 (35%), Gaps = 40/270 (14%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS---YTCLCEP 67
C ++ F C C PG+ G C ++D C P G C TAGS + C C
Sbjct: 1023 CHSLANAFYCQCLPGHT----GQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPK 1077
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNS-EGSF--QCVCEAGY------RPTATRGAC 118
GF + A C GG C+ S + F +C C +GY P A +G C
Sbjct: 1078 GFEGPTCSHRAP--SCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG-C 1134
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDG-RTCLGLKLGWGVSCQACP 174
C C PG FRC C PG G + C G + G G C
Sbjct: 1135 GPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRCQKPGAKGCEG-RSGDGACDAGCS 1192
Query: 175 AQGSELYAVLCPEG-PSKDNGGADINECTAV--PGACPHGSCENLE---PGYRCICDPGY 228
G C G P G + C + G C H C++ E GY C P
Sbjct: 1193 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQC-HPQCDSEECLFDGYDCETPPAC 1251
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTA 258
P D C D H +C G C NTA
Sbjct: 1252 TPAYDQYCHD----HFHNGHCEKG-C-NTA 1275
Score = 33.1 bits (72), Expect = 2.1
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPG 441
DG C +++D C ++ C GTC G + C CPPG
Sbjct: 961 DGQNCSKELDAC--QSQPCHNHGTCTPKPGGFHCACPPG 997
Score = 32.7 bits (71), Expect = 2.7
Identities = 14/38 (36%), Positives = 17/38 (44%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G TC + S GG+C + G Y C CPP T
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 128 bits (309), Expect = 4e-29
Identities = 135/476 (28%), Positives = 186/476 (39%), Gaps = 75/476 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRG-RCRNTAGS 60
NGG C +G+ + C+C E+ + DVDEC P CR G C+N+AGS
Sbjct: 286 NGGTCQDGL-----DTYTCLCP---ETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGS 337
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C+C G+ T+ ++D+C A + G C++ GSF C+C G T C
Sbjct: 338 FHCVCVSGWGGTSCE--ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGLLCHL 391
Query: 121 VDECEEQRVCRNGRCHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLG-----WGVSC 170
D C Q + +C P GS C C PG+ T D CL + G G SC
Sbjct: 392 EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 451
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
P GS + LCP G + AD NEC + P P +C +L + C+C PG
Sbjct: 452 LNTP--GS--FNCLCPPGYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGLEG 506
Query: 231 DADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEG 286
LC +++ + + C C + F C+C P GTR E ++ CR G
Sbjct: 507 Q---LC-EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANG 562
Query: 287 ---ETETHYIESDYERGDIPPTFPTRTE--LASPCDNGR-CINTHGGFECECELGYV--- 337
+ + G P T + L+ PC G C++ G F C C G+
Sbjct: 563 GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQL 622
Query: 338 ---------LDATAQRCLDNR-RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
L Q C D + + +C DG A PE C C G S
Sbjct: 623 CEVPLCAPNLCQPKQICKDQKDKANCL--CPDGSPGCAPPE----DNCTCHHGHCQRSSC 676
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ G C +SA GGTC Y C CP G T
Sbjct: 677 VCDV--------GWT---GPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 721
Score = 120 bits (289), Expect = 1e-26
Identities = 115/419 (27%), Positives = 155/419 (36%), Gaps = 71/419 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
G C N G F C+C PGY G+ C D +EC P C G C + ++ CLC P
Sbjct: 449 GSCLNTPGSFNCLCPPGYT----GSRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPP 502
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
G + +ECA+ C + FQC+C G+ T D+DEC
Sbjct: 503 GLEGQLCE--VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE---DIDECRSS 557
Query: 128 RVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
G+C + PG+F C+CLPGF + CL G SC P + L
Sbjct: 558 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA----FFCL 613
Query: 185 CPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCIC---DPGYHPDAD------G 234
CP G + ++ C P C P C++ + C+C PG P D G
Sbjct: 614 CPSGFTGQL--CEVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHG 669
Query: 235 LCR------DID----ECDMHQSYCA------GGQCRNTAGSFTCVCPEGTRH---EPEL 275
C+ D+ EC+ C GG C + C CP G E+
Sbjct: 670 HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 729
Query: 276 QLCRDIDECEGETETHYIESDYERGDIP----PTFPTRTE--LASPCDNG-RCINTHGGF 328
C C + Y P P T T+ +++PC NG C+N G F
Sbjct: 730 TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTF 788
Query: 329 ECECELGYVLDATAQRCLDNRRGSCWRRVVDGQC--EAAAPELLLRQECCCSVGLAWGS 385
C C +G+ RC R SC D C A + C C G GS
Sbjct: 789 SCLCAMGF----QGPRCEGKLRPSC----ADSPCRNRATCQDSPQGPRCLCPTGYTGGS 839
Score = 120 bits (288), Expect = 1e-26
Identities = 127/440 (28%), Positives = 175/440 (39%), Gaps = 51/440 (11%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCR-NTAGSYTCLCEPGFAPTAAGY 76
F C C PG+ E + D C P C +RGRC +G C C PG+
Sbjct: 100 FLCTCLPGFTG--ERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT---GEQ 152
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNG-R 134
C D C+A+ GG C+ + QC C G+ A DV+EC ++ C G
Sbjct: 153 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS 209
Query: 135 CHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
CHNT GSF+C C G C G +CQ P + S + LCP P
Sbjct: 210 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP--PGF 267
Query: 192 DNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH-QSYC 249
G ++N V C + G+C++ Y C+C P D D+DEC+ +C
Sbjct: 268 IGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC-PETWTGWD-CSEDVDECEAQGPPHC 325
Query: 250 A-GGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
GG C+N+AGSF CVC GT E L C G T I+ + P
Sbjct: 326 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGST---CIDRVGSFSCLCP- 381
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
P RT L ++ C++ + +C + +T C G C
Sbjct: 382 -PGRTGLLCHLED-MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP--------TCHQD 431
Query: 366 APELLLRQE--CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELC 422
E L+ Q+ C G GS G+ G+ C D +EC LS
Sbjct: 432 LDECLMAQQGPSPCEHG---GSCLNTPGSFNCLCPPGYT---GSRCEADHNEC-LSQPCH 484
Query: 423 AGGTCVNTDGSYRCDCPPGL 442
G TC++ ++ C CPPGL
Sbjct: 485 PGSTCLDLLATFHCLCPPGL 504
Score = 119 bits (287), Expect = 2e-26
Identities = 130/465 (27%), Positives = 183/465 (39%), Gaps = 62/465 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRR-GRCRNT--AGSYT 62
C G C + G F C+C PG G LC D C P C +C GS
Sbjct: 363 CAPGSTCIDRVGSFSCLCPPG----RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTL 416
Query: 63 CLCEPGFA-PTAAGYCADVDECA----ADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRG 116
CLC+PG++ PT D+DEC S C+ GG C+N+ GSF C+C GY T +R
Sbjct: 417 CLCQPGYSGPTCH---QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSR- 470
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP-- 174
D +EC Q C + +F C C PG +G+ C ++ C + P
Sbjct: 471 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGL----EGQLC-EVETN---ECASAPCL 522
Query: 175 --AQGSEL---YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A +L + +C G S DI+EC + P A G C++ + C C PG+
Sbjct: 523 NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCA-NGGQCQDQPGAFHCKCLPGF- 580
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPEL-----QLCRDIDE 283
+ ++DEC + G C + G+F C+CP G T E+ LC+
Sbjct: 581 -EGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQI 638
Query: 284 CEGETE-THYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG--GFECECELGYVLDA 340
C+ + + + + D G PP T C C+ G G ECE ELG + A
Sbjct: 639 CKDQKDKANCLCPDGSPGCAPPE-DNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISA 697
Query: 341 TAQRCLDNRRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
C G+C+ + C P C S G
Sbjct: 698 P---CAHG--GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 752
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C+ + +SA GGTCVN G++ C C G
Sbjct: 753 TCP--PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 795
Score = 112 bits (270), Expect = 2e-24
Identities = 139/473 (29%), Positives = 190/473 (40%), Gaps = 89/473 (18%)
Query: 5 GMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCR----NT 57
G C G C N G F+C+C G EG C C PR C G C+
Sbjct: 202 GPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCP--PRGCSNGGTCQLMPEKD 255
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ + CLC PGF G + D C + GG C + ++ C+C T T
Sbjct: 256 STFHLCLCPPGFI--GPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPE----TWTGWD 309
Query: 118 CV-DVDECEEQRV--CRNG-RCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSC 170
C DVDECE Q CRNG C N+ GSF C C+ G+ + + C+ G +C
Sbjct: 310 CSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 369
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG----SCENLEPGYRCICDP 226
GS ++ LCP G + + + C + P C HG S L C+C P
Sbjct: 370 --IDRVGS--FSCLCPPGRTGLLCHLE-DMCLSQP--C-HGDAQCSTNPLTGSTLCLCQP 421
Query: 227 GYHPDADGLC-RDIDECDMHQ---SYCA-GGQCRNTAGSFTCVCP---EGTRHEPE---- 274
GY + C +D+DEC M Q S C GG C NT GSF C+CP G+R E +
Sbjct: 422 GY---SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 478
Query: 275 -LQLCRDIDECEGETET-HYIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECE 331
Q C C T H + G + T ++PC ++ C + GF+C
Sbjct: 479 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV-ETNECASAPCLNHADCHDLLNGFQCI 537
Query: 332 CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
C G+ + +D R S GQC+ C C G
Sbjct: 538 CLPGF-SGTRCEEDIDECRSSPCAN--GGQCQDQPGAF----HCKCLPG----------- 579
Query: 392 XXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G C+ +VDEC LS G +C++ G++ C CP G T
Sbjct: 580 ------------FEGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFT 619
Score = 111 bits (267), Expect = 5e-24
Identities = 104/354 (29%), Positives = 140/354 (39%), Gaps = 42/354 (11%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS 60
+ G C NG C GG+ C C P + G C+ D C P G C N G+
Sbjct: 733 HSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTDYCVSAP-CFNGGTCVNRPGT 787
Query: 61 YTCLCEPGF-APTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGAC 118
++CLC GF P G + ADS C+ C +S +C+C GY T G+C
Sbjct: 788 FSCLCAMGFQGPRCEG---KLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TGGSC 840
Query: 119 VD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSN-DGRTCLGLKLGWGVSCQACP 174
+D C ++ RN C T SF C CL G+T L N +C L G+ +
Sbjct: 841 QTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 900
Query: 175 AQG------SELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPG 227
G Y CP G +N C + P C +G +C GY C C PG
Sbjct: 901 HNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPG 958
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDEC 284
Y D +++D C + G C G F C CP G R E ++ C D C
Sbjct: 959 Y--DGQNCSKELDACQSQPCH-NHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD-QPC 1014
Query: 285 E--GETETHYIESDYERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELG 335
G H + + + +P E+ PC + C HGG CE G
Sbjct: 1015 HPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCF--HGG-TCEATAG 1065
Score = 110 bits (265), Expect = 9e-24
Identities = 119/470 (25%), Positives = 177/470 (37%), Gaps = 78/470 (16%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C ++ GF+CIC PG+ G C D+DECR +P G+C++ G++ C C PGF
Sbjct: 527 CHDLLNGFQCICLPGFS----GTRCEEDIDECRSSP-CANGGQCQDQPGAFHCKCLPGFE 581
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR------PTATRGACVDVDEC 124
+VDEC +D G C++ G+F C+C +G+ P C C
Sbjct: 582 GPRCQ--TEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 639
Query: 125 EEQR-----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-GVSCQA------ 172
++Q+ +C +G P C C G + +C+ +GW G C+A
Sbjct: 640 KDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS---SCV-CDVGWTGPECEAELGGCI 695
Query: 173 ---CPAQGS-----ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
C G+ Y CP G + ++ C + P GSC GY C C
Sbjct: 696 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP-CLNGGSCNPSPGGYYCTC 754
Query: 225 DPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQL---- 277
P + C+ + + GG C N G+F+C+C +G R E +L+
Sbjct: 755 PPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 811
Query: 278 --CRDIDECEGETETH--YIESDYERGDIPPTFPTRTELASPCD-NGRCINTHGGFECEC 332
CR+ C+ + + Y G + PC N C+ T F C C
Sbjct: 812 SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQ--KPCPRNSHCLQTGPSFHCLC 869
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
G+ T C + C+ AA + C G G
Sbjct: 870 LQGW----TGPLC----------NLPLSSCQKAALSQGIDVSSLCHNG---GLCVDSGPS 912
Query: 393 XXXXXXKGFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G+ C+D V+ C S G TC+ Y C C PG
Sbjct: 913 YFCHCPPGF---QGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQCAPG 958
Score = 99 bits (238), Expect = 2e-20
Identities = 120/461 (26%), Positives = 170/461 (36%), Gaps = 71/461 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTC 63
C NG +C +C C PG+ EG C RDV+EC +P C +G C NT GS+ C
Sbjct: 164 CVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 219
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRC---VNSEGSFQ-CVCEAGYRPTATRGACV 119
LC G A C GG C + +F C+C G+ G V
Sbjct: 220 LCPVGQEGPRCELRA--GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF---IGPGCEV 274
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ D C + G C + ++ C C G+ S D C + C
Sbjct: 275 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNS 334
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ V C G + ++++C A A P +C + + C+C PG GL
Sbjct: 335 AGSFHCV-CVSGWGGTSCEENLDDCIAATCA-PGSTCIDRVGSFSCLCPPG----RTGLL 388
Query: 237 RDIDECDMHQSYCAGGQCRNT--AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
+++ + Q QC GS C+C G P +D+DEC
Sbjct: 389 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPG-YSGPTCH--QDLDEC---------- 435
Query: 295 SDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLDN-- 348
++G SPC++ G C+NT G F C C GY +A CL
Sbjct: 436 LMAQQG------------PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPC 483
Query: 349 RRGS-CWRRVVDGQCEAAAPEL------LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GS C + C P L + EC + L GF
Sbjct: 484 HPGSTCLDLLATFHC-LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 542
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ G C D+DEC S+ GG C + G++ C C PG
Sbjct: 543 S---GTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKCLPG 579
Score = 90.6 bits (215), Expect = 1e-17
Identities = 127/462 (27%), Positives = 170/462 (36%), Gaps = 81/462 (17%)
Query: 42 CRDNPRVCRRG-RCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCV--- 95
C P C G C + + G TC C PGF C D C +C+ GG C
Sbjct: 27 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQALL 83
Query: 96 -------NSEG----SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH-NTPGSFR 143
+S SF C C G+ T R D C + GRCH G +
Sbjct: 84 PAPLGLPSSPSPLTPSFLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 141
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--YAVL---CPEGPSKDNGGADI 198
C C+PG+T G C +L S C G L Y + CP G D+
Sbjct: 142 CSCMPGWT----GEQC---QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 194
Query: 199 NECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCR- 255
NEC PG CP G SC N ++C+C G +G ++ C+ GG C+
Sbjct: 195 NECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQL 250
Query: 256 ---NTAGSFTCVCP-----EGTRHEPE---LQLCRDIDECEG--ETETHYIESDYERGDI 302
+ C+CP G P+ C++ C+ +T T + D
Sbjct: 251 MPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 310
Query: 303 PPTFPTRTELASP-CDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGS 352
P C N G C N+ G F C C G+ + D A C +
Sbjct: 311 SEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG--ST 368
Query: 353 CWRRV--VDGQCEAAAPELLLRQECCC----SVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
C RV C LL E C G A S G++ G
Sbjct: 369 CIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS---G 425
Query: 407 ATC-RDVDECALSAE---LCA-GGTCVNTDGSYRCDCPPGLT 443
TC +D+DEC ++ + C GG+C+NT GS+ C CPPG T
Sbjct: 426 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 467
Score = 88.6 bits (210), Expect = 4e-17
Identities = 90/353 (25%), Positives = 130/353 (36%), Gaps = 59/353 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C G+ C C GY G C ++ C P + G C + G Y C C P
Sbjct: 703 GTCYPQPSGYNCTCPTGYT----GPTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPS 757
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
T D C + GG CVN G+F C+C G++ G C +
Sbjct: 758 H--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--RPSCADS- 812
Query: 129 VCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
CRN C ++P RC C G+T +T + L + Q + LC +
Sbjct: 813 PCRNRATCQDSPQGPRCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 871
Query: 188 G--------PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRD 238
G P A +++ V C +G C + P Y C C PG+ LC+D
Sbjct: 872 GWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ---GSLCQD 928
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
H + C C+N A TC+ +P LC+ +G+ + +++
Sbjct: 929 ------HVNPCESRPCQNGA---TCMA------QPSGYLCQCAPGYDGQNCSKELDACQ- 972
Query: 299 RGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLD 347
+ PC N G C GGF C C G+V + CLD
Sbjct: 973 --------------SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD 1011
Score = 73.3 bits (172), Expect = 2e-12
Identities = 70/264 (26%), Positives = 97/264 (36%), Gaps = 35/264 (13%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECR--------DNPRVCRRGR-CRNTA 58
N C F C+C G+ G LC + C+ D +C G C ++
Sbjct: 855 NSHCLQTGPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSG 910
Query: 59 GSYTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
SY C C PGF C D V+ C + G C+ + C C GY +
Sbjct: 911 PSYFCHCPPGFQ---GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDG---QNC 964
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACP 174
++D C+ Q +G C PG F C C PGF D CL AC
Sbjct: 965 SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPC-HPTGTAACH 1023
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENL--EP-GYRCICDPGYHP 230
+ + Y C G + +I+ C + P C H G+CE P G+ C C G+
Sbjct: 1024 SLANAFYC-QCLPGHTGQWCEVEIDPCHSQP--CFHGGTCEATAGSPLGFICHCPKGF-- 1078
Query: 231 DADGLCRDIDECDMHQSYCAGGQC 254
+ C H + GG C
Sbjct: 1079 EGPTCSHRAPSCGFHHCH-HGGLC 1101
Score = 62.5 bits (145), Expect = 3e-09
Identities = 78/270 (28%), Positives = 97/270 (35%), Gaps = 40/270 (14%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS---YTCLCEP 67
C ++ F C C PG+ G C ++D C P G C TAGS + C C
Sbjct: 1022 CHSLANAFYCQCLPGHT----GQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPK 1076
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNS-EGSF--QCVCEAGY------RPTATRGAC 118
GF + A C GG C+ S + F +C C +GY P A +G C
Sbjct: 1077 GFEGPTCSHRAP--SCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG-C 1133
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDG-RTCLGLKLGWGVSCQACP 174
C C PG FRC C PG G + C G + G G C
Sbjct: 1134 GPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRCQKPGAKGCEG-RSGDGACDAGCS 1191
Query: 175 AQGSELYAVLCPEG-PSKDNGGADINECTAV--PGACPHGSCENLE---PGYRCICDPGY 228
G C G P G + C + G C H C++ E GY C P
Sbjct: 1192 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQC-HPQCDSEECLFDGYDCETPPAC 1250
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTA 258
P D C D H +C G C NTA
Sbjct: 1251 TPAYDQYCHD----HFHNGHCEKG-C-NTA 1274
Score = 33.1 bits (72), Expect = 2.1
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPG 441
DG C +++D C ++ C GTC G + C CPPG
Sbjct: 960 DGQNCSKELDAC--QSQPCHNHGTCTPKPGGFHCACPPG 996
Score = 32.7 bits (71), Expect = 2.7
Identities = 14/38 (36%), Positives = 17/38 (44%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G TC + S GG+C + G Y C CPP T
Sbjct: 722 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 759
>D86566-1|BAA13116.1| 955|Homo sapiens notch related protein
protein.
Length = 955
Score = 128 bits (309), Expect = 4e-29
Identities = 135/476 (28%), Positives = 186/476 (39%), Gaps = 75/476 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRG-RCRNTAGS 60
NGG C +G+ + C+C E+ + DVDEC P CR G C+N+AGS
Sbjct: 287 NGGTCQDGL-----DTYTCLCP---ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C+C G+ T+ ++D+C A + G C++ GSF C+C G T C
Sbjct: 339 FHCVCVSGWGGTSCE--ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGLLCHL 392
Query: 121 VDECEEQRVCRNGRCHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLG-----WGVSC 170
D C Q + +C P GS C C PG+ T D CL + G G SC
Sbjct: 393 EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 452
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
P GS + LCP G + AD NEC + P P +C +L + C+C PG
Sbjct: 453 LNTP--GS--FNCLCPPGYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGLEG 507
Query: 231 DADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEG 286
LC +++ + + C C + F C+C P GTR E ++ CR G
Sbjct: 508 Q---LC-EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANG 563
Query: 287 ---ETETHYIESDYERGDIPPTFPTRTE--LASPCDNGR-CINTHGGFECECELGYV--- 337
+ + G P T + L+ PC G C++ G F C C G+
Sbjct: 564 GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQL 623
Query: 338 ---------LDATAQRCLDNR-RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
L Q C D + + +C DG A PE C C G S
Sbjct: 624 CEVPLCAPNLCQPKQICKDQKDKANCL--CPDGSPGCAPPE----DNCTCHHGHCQRSSC 677
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ G C +SA GGTC Y C CP G T
Sbjct: 678 VCDV--------GWT---GPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 722
Score = 120 bits (289), Expect = 1e-26
Identities = 115/419 (27%), Positives = 155/419 (36%), Gaps = 71/419 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
G C N G F C+C PGY G+ C D +EC P C G C + ++ CLC P
Sbjct: 450 GSCLNTPGSFNCLCPPGYT----GSRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPP 503
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
G + +ECA+ C + FQC+C G+ T D+DEC
Sbjct: 504 GLEGQLCE--VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE---DIDECRSS 558
Query: 128 RVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
G+C + PG+F C+CLPGF + CL G SC P + L
Sbjct: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA----FFCL 614
Query: 185 CPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCIC---DPGYHPDAD------G 234
CP G + ++ C P C P C++ + C+C PG P D G
Sbjct: 615 CPSGFTGQL--CEVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHG 670
Query: 235 LCR------DID----ECDMHQSYCA------GGQCRNTAGSFTCVCPEGTRH---EPEL 275
C+ D+ EC+ C GG C + C CP G E+
Sbjct: 671 HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
Query: 276 QLCRDIDECEGETETHYIESDYERGDIP----PTFPTRTE--LASPCDNG-RCINTHGGF 328
C C + Y P P T T+ +++PC NG C+N G F
Sbjct: 731 TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTF 789
Query: 329 ECECELGYVLDATAQRCLDNRRGSCWRRVVDGQC--EAAAPELLLRQECCCSVGLAWGS 385
C C +G+ RC R SC D C A + C C G GS
Sbjct: 790 SCLCAMGF----QGPRCEGKLRPSC----ADSPCRNRATCQDSPQGPRCLCPTGYTGGS 840
Score = 119 bits (287), Expect = 2e-26
Identities = 130/465 (27%), Positives = 183/465 (39%), Gaps = 62/465 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRR-GRCRNT--AGSYT 62
C G C + G F C+C PG G LC D C P C +C GS
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPG----RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTL 417
Query: 63 CLCEPGFA-PTAAGYCADVDECA----ADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRG 116
CLC+PG++ PT D+DEC S C+ GG C+N+ GSF C+C GY T +R
Sbjct: 418 CLCQPGYSGPTCH---QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSR- 471
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP-- 174
D +EC Q C + +F C C PG +G+ C ++ C + P
Sbjct: 472 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGL----EGQLC-EVETN---ECASAPCL 523
Query: 175 --AQGSEL---YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A +L + +C G S DI+EC + P A G C++ + C C PG+
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCA-NGGQCQDQPGAFHCKCLPGF- 581
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPEL-----QLCRDIDE 283
+ ++DEC + G C + G+F C+CP G T E+ LC+
Sbjct: 582 -EGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQI 639
Query: 284 CEGETE-THYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG--GFECECELGYVLDA 340
C+ + + + + D G PP T C C+ G G ECE ELG + A
Sbjct: 640 CKDQKDKANCLCPDGSPGCAPPE-DNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISA 698
Query: 341 TAQRCLDNRRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
C G+C+ + C P C S G
Sbjct: 699 P---CAHG--GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C+ + +SA GGTCVN G++ C C G
Sbjct: 754 TCP--PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
Score = 117 bits (281), Expect = 1e-25
Identities = 126/440 (28%), Positives = 174/440 (39%), Gaps = 51/440 (11%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCR-NTAGSYTCLCEPGFAPTAAGY 76
F C C PG+ G C+ E P C +RGRC +G C C PG+
Sbjct: 101 FLCTCLPGFT----GERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWT---GEQ 153
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNG-R 134
C D C+A+ GG C+ + QC C G+ A DV+EC ++ C G
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS 210
Query: 135 CHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
CHNT GSF+C C G C G +CQ P + S + LCP P
Sbjct: 211 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP--PGF 268
Query: 192 DNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH-QSYC 249
++N V C + G+C++ Y C+C P D D+DEC+ +C
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC-PETWTGWD-CSEDVDECETQGPPHC 326
Query: 250 A-GGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
GG C+N+AGSF CVC GT E L C G T I+ + P
Sbjct: 327 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGST---CIDRVGSFSCLCP- 382
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
P RT L ++ C++ + +C + +T C G C
Sbjct: 383 -PGRTGLLCHLED-MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP--------TCHQD 432
Query: 366 APELLLRQE--CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELC 422
E L+ Q+ C G GS G+ G+ C D +EC LS
Sbjct: 433 LDECLMAQQGPSPCEHG---GSCLNTPGSFNCLCPPGYT---GSRCEADHNEC-LSQPCH 485
Query: 423 AGGTCVNTDGSYRCDCPPGL 442
G TC++ ++ C CPPGL
Sbjct: 486 PGSTCLDLLATFHCLCPPGL 505
Score = 110 bits (264), Expect = 1e-23
Identities = 138/473 (29%), Positives = 189/473 (39%), Gaps = 89/473 (18%)
Query: 5 GMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCR----NT 57
G C G C N G F+C+C G EG C C PR C G C+
Sbjct: 203 GPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCP--PRGCSNGGTCQLMPEKD 256
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ + CLC PGF + D C + GG C + ++ C+C T T
Sbjct: 257 STFHLCLCPPGFIGPDCE--VNPDNCVSHQCQNGGTCQDGLDTYTCLCPE----TWTGWD 310
Query: 118 CV-DVDECEEQRV--CRNG-RCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSC 170
C DVDECE Q CRNG C N+ GSF C C+ G+ + + C+ G +C
Sbjct: 311 CSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG----SCENLEPGYRCICDP 226
GS ++ LCP G + + + C + P C HG S L C+C P
Sbjct: 371 --IDRVGS--FSCLCPPGRTGLLCHLE-DMCLSQP--C-HGDAQCSTNPLTGSTLCLCQP 422
Query: 227 GYHPDADGLC-RDIDECDMHQ---SYCA-GGQCRNTAGSFTCVCP---EGTRHEPE---- 274
GY + C +D+DEC M Q S C GG C NT GSF C+CP G+R E +
Sbjct: 423 GY---SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 479
Query: 275 -LQLCRDIDECEGETET-HYIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECE 331
Q C C T H + G + T ++PC ++ C + GF+C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV-ETNECASAPCLNHADCHDLLNGFQCI 538
Query: 332 CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
C G+ + +D R S GQC+ C C G
Sbjct: 539 CLPGF-SGTRCEEDIDECRSSPCAN--GGQCQDQPGAF----HCKCLPG----------- 580
Query: 392 XXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G C+ +VDEC LS G +C++ G++ C CP G T
Sbjct: 581 ------------FEGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFT 620
Score = 108 bits (259), Expect = 5e-23
Identities = 94/363 (25%), Positives = 145/363 (39%), Gaps = 54/363 (14%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C ++ GF+CIC PG+ G C D+DECR +P G+C++ G++ C C PGF
Sbjct: 528 CHDLLNGFQCICLPGFS----GTRCEEDIDECRSSP-CANGGQCQDQPGAFHCKCLPGFE 582
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR------PTATRGACVDVDEC 124
+VDEC +D G C++ G+F C+C +G+ P C C
Sbjct: 583 GPRCQ--TEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 640
Query: 125 EEQR-----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-GVSCQA------ 172
++Q+ +C +G P C C G + +C+ +GW G C+A
Sbjct: 641 KDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS---SCV-CDVGWTGPECEAELGGCI 696
Query: 173 ---CPAQGS-----ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
C G+ Y CP G + ++ C + P GSC GY C C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP-CLNGGSCNPSPGGYYCTC 755
Query: 225 DPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQL---- 277
P + C+ + + GG C N G+F+C+C +G R E +L+
Sbjct: 756 PPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 812
Query: 278 --CRDIDECEGETETH--YIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECE 333
CR+ C+ + + Y G + P N C+ T F C C
Sbjct: 813 SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQRPCP-RNSHCLQTGPSFHCLCL 871
Query: 334 LGY 336
G+
Sbjct: 872 QGW 874
Score = 96.7 bits (230), Expect = 1e-19
Identities = 119/461 (25%), Positives = 169/461 (36%), Gaps = 71/461 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTC 63
C NG +C +C C PG+ EG C RDV+EC +P C +G C NT GS+ C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 220
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRC---VNSEGSFQ-CVCEAGYRPTATRGACV 119
LC G A C GG C + +F C+C G+ V
Sbjct: 221 LCPVGQEGPRCELRA--GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---V 275
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ D C + G C + ++ C C G+ S D C + C
Sbjct: 276 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ V C G + ++++C A A P +C + + C+C PG GL
Sbjct: 336 AGSFHCV-CVSGWGGTSCEENLDDCIAATCA-PGSTCIDRVGSFSCLCPPG----RTGLL 389
Query: 237 RDIDECDMHQSYCAGGQCRNT--AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
+++ + Q QC GS C+C G P +D+DEC
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPG-YSGPTCH--QDLDEC---------- 436
Query: 295 SDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLDN-- 348
++G SPC++ G C+NT G F C C GY +A CL
Sbjct: 437 LMAQQG------------PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPC 484
Query: 349 RRGS-CWRRVVDGQCEAAAPEL------LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GS C + C P L + EC + L GF
Sbjct: 485 HPGSTCLDLLATFHC-LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ G C D+DEC S+ GG C + G++ C C PG
Sbjct: 544 S---GTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKCLPG 580
Score = 90.6 bits (215), Expect = 1e-17
Identities = 127/462 (27%), Positives = 171/462 (37%), Gaps = 81/462 (17%)
Query: 42 CRDNPRVCRRG-RCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCV--- 95
C P C G C + + G TC C PGF C D C +C+ GG C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQALL 84
Query: 96 -------NSEG----SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH-NTPGSFR 143
+S SF C C G+ T R D C + GRCH G +
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLPGF--TGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQ 142
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--YAVL---CPEGPSKDNGGADI 198
C C+PG+T G C +L S C G L Y + CP G D+
Sbjct: 143 CSCMPGWT----GEQC---QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 195
Query: 199 NECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCR- 255
NEC PG CP G SC N ++C+C G +G ++ C+ GG C+
Sbjct: 196 NECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQL 251
Query: 256 ---NTAGSFTCVCPEG-----TRHEPE---LQLCRDIDECEG--ETETHYIESDYERGDI 302
+ C+CP G P+ C++ C+ +T T + D
Sbjct: 252 MPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 311
Query: 303 PPTF-PTRTELASPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGS 352
T+ C N G C N+ G F C C G+ + D A C +
Sbjct: 312 SEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG--ST 369
Query: 353 CWRRV--VDGQCEAAAPELLLRQECCC----SVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
C RV C LL E C G A S G++ G
Sbjct: 370 CIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS---G 426
Query: 407 ATC-RDVDECALSAE---LCA-GGTCVNTDGSYRCDCPPGLT 443
TC +D+DEC ++ + C GG+C+NT GS+ C CPPG T
Sbjct: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
Score = 81.0 bits (191), Expect = 8e-15
Identities = 73/271 (26%), Positives = 102/271 (37%), Gaps = 35/271 (12%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C G+ C C GY G C ++ C P + G C + G Y C C P
Sbjct: 704 GTCYPQPSGYNCTCPTGYT----GPTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPS 758
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
T D C + GG CVN G+F C+C G++ G C +
Sbjct: 759 H--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--RPSCADS- 813
Query: 129 VCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
CRN C ++P RC C G+T +T + L + Q + LC +
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYT-GGSCQTLMDLCAQRPCPRNSHCLQTGPSFHCLCLQ 872
Query: 188 G--------PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRD 238
G P A +++ V C +G C + P Y C C PG+ LC+D
Sbjct: 873 GWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ---GSLCQD 929
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVC-PEG 268
H + C C+N A TC+ P G
Sbjct: 930 ------HVNPCESRPCQNGA---TCMAQPSG 951
Score = 32.7 bits (71), Expect = 2.7
Identities = 14/38 (36%), Positives = 17/38 (44%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G TC + S GG+C + G Y C CPP T
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 128 bits (309), Expect = 4e-29
Identities = 135/476 (28%), Positives = 186/476 (39%), Gaps = 75/476 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRG-RCRNTAGS 60
NGG C +G+ + C+C E+ + DVDEC P CR G C+N+AGS
Sbjct: 287 NGGTCQDGL-----DTYTCLCP---ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C+C G+ T+ ++D+C A + G C++ GSF C+C G T C
Sbjct: 339 FHCVCVSGWGGTSCE--ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGLLCHL 392
Query: 121 VDECEEQRVCRNGRCHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLG-----WGVSC 170
D C Q + +C P GS C C PG+ T D CL + G G SC
Sbjct: 393 EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 452
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
P GS + LCP G + AD NEC + P P +C +L + C+C PG
Sbjct: 453 LNTP--GS--FNCLCPPGYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGLEG 507
Query: 231 DADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEG 286
LC +++ + + C C + F C+C P GTR E ++ CR G
Sbjct: 508 Q---LC-EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANG 563
Query: 287 ---ETETHYIESDYERGDIPPTFPTRTE--LASPCDNGR-CINTHGGFECECELGYV--- 337
+ + G P T + L+ PC G C++ G F C C G+
Sbjct: 564 GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQL 623
Query: 338 ---------LDATAQRCLDNR-RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
L Q C D + + +C DG A PE C C G S
Sbjct: 624 CEVPLCAPNLCQPKQICKDQKDKANCL--CPDGSPGCAPPE----DNCTCHHGHCQRSSC 677
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ G C +SA GGTC Y C CP G T
Sbjct: 678 VCDV--------GWT---GPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 722
Score = 120 bits (289), Expect = 1e-26
Identities = 115/419 (27%), Positives = 155/419 (36%), Gaps = 71/419 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
G C N G F C+C PGY G+ C D +EC P C G C + ++ CLC P
Sbjct: 450 GSCLNTPGSFNCLCPPGYT----GSRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPP 503
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
G + +ECA+ C + FQC+C G+ T D+DEC
Sbjct: 504 GLEGQLCE--VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE---DIDECRSS 558
Query: 128 RVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
G+C + PG+F C+CLPGF + CL G SC P + L
Sbjct: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA----FFCL 614
Query: 185 CPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCIC---DPGYHPDAD------G 234
CP G + ++ C P C P C++ + C+C PG P D G
Sbjct: 615 CPSGFTGQL--CEVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHG 670
Query: 235 LCR------DID----ECDMHQSYCA------GGQCRNTAGSFTCVCPEGTRH---EPEL 275
C+ D+ EC+ C GG C + C CP G E+
Sbjct: 671 HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
Query: 276 QLCRDIDECEGETETHYIESDYERGDIP----PTFPTRTE--LASPCDNG-RCINTHGGF 328
C C + Y P P T T+ +++PC NG C+N G F
Sbjct: 731 TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTF 789
Query: 329 ECECELGYVLDATAQRCLDNRRGSCWRRVVDGQC--EAAAPELLLRQECCCSVGLAWGS 385
C C +G+ RC R SC D C A + C C G GS
Sbjct: 790 SCLCAMGF----QGPRCEGKLRPSC----ADSPCRNRATCQDSPQGPRCLCPTGYTGGS 840
Score = 119 bits (287), Expect = 2e-26
Identities = 130/465 (27%), Positives = 183/465 (39%), Gaps = 62/465 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRR-GRCRNT--AGSYT 62
C G C + G F C+C PG G LC D C P C +C GS
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPG----RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTL 417
Query: 63 CLCEPGFA-PTAAGYCADVDECA----ADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRG 116
CLC+PG++ PT D+DEC S C+ GG C+N+ GSF C+C GY T +R
Sbjct: 418 CLCQPGYSGPTCH---QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSR- 471
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP-- 174
D +EC Q C + +F C C PG +G+ C ++ C + P
Sbjct: 472 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGL----EGQLC-EVETN---ECASAPCL 523
Query: 175 --AQGSEL---YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A +L + +C G S DI+EC + P A G C++ + C C PG+
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCA-NGGQCQDQPGAFHCKCLPGF- 581
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPEL-----QLCRDIDE 283
+ ++DEC + G C + G+F C+CP G T E+ LC+
Sbjct: 582 -EGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQI 639
Query: 284 CEGETE-THYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG--GFECECELGYVLDA 340
C+ + + + + D G PP T C C+ G G ECE ELG + A
Sbjct: 640 CKDQKDKANCLCPDGSPGCAPPE-DNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISA 698
Query: 341 TAQRCLDNRRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
C G+C+ + C P C S G
Sbjct: 699 P---CAHG--GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C+ + +SA GGTCVN G++ C C G
Sbjct: 754 TCP--PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
Score = 117 bits (281), Expect = 1e-25
Identities = 126/440 (28%), Positives = 174/440 (39%), Gaps = 51/440 (11%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCR-NTAGSYTCLCEPGFAPTAAGY 76
F C C PG+ E + D C P C +RGRC +G C C PG+
Sbjct: 101 FLCTCLPGFTG--ERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT---GEQ 153
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNG-R 134
C D C+A+ GG C+ + QC C G+ A DV+EC ++ C G
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS 210
Query: 135 CHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
CHNT GSF+C C G C G +CQ P + S + LCP P
Sbjct: 211 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP--PGF 268
Query: 192 DNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH-QSYC 249
++N V C + G+C++ Y C+C P D D+DEC+ +C
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC-PETWTGWD-CSEDVDECETQGPPHC 326
Query: 250 A-GGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
GG C+N+AGSF CVC GT E L C G T I+ + P
Sbjct: 327 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGST---CIDRVGSFSCLCP- 382
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
P RT L ++ C++ + +C + +T C G C
Sbjct: 383 -PGRTGLLCHLED-MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP--------TCHQD 432
Query: 366 APELLLRQE--CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELC 422
E L+ Q+ C G GS G+ G+ C D +EC LS
Sbjct: 433 LDECLMAQQGPSPCEHG---GSCLNTPGSFNCLCPPGYT---GSRCEADHNEC-LSQPCH 485
Query: 423 AGGTCVNTDGSYRCDCPPGL 442
G TC++ ++ C CPPGL
Sbjct: 486 PGSTCLDLLATFHCLCPPGL 505
Score = 111 bits (267), Expect = 5e-24
Identities = 104/354 (29%), Positives = 140/354 (39%), Gaps = 42/354 (11%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS 60
+ G C NG C GG+ C C P + G C+ D C P G C N G+
Sbjct: 734 HSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTDYCVSAP-CFNGGTCVNRPGT 788
Query: 61 YTCLCEPGF-APTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGAC 118
++CLC GF P G + ADS C+ C +S +C+C GY T G+C
Sbjct: 789 FSCLCAMGFQGPRCEG---KLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TGGSC 841
Query: 119 VD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSN-DGRTCLGLKLGWGVSCQACP 174
+D C ++ RN C T SF C CL G+T L N +C L G+ +
Sbjct: 842 QTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 901
Query: 175 AQG------SELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPG 227
G Y CP G +N C + P C +G +C GY C C PG
Sbjct: 902 HNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPG 959
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDEC 284
Y D +++D C + G C G F C CP G R E ++ C D C
Sbjct: 960 Y--DGQNCSKELDACQSQPCH-NHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD-QPC 1015
Query: 285 E--GETETHYIESDYERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELG 335
G H + + + +P E+ PC + C HGG CE G
Sbjct: 1016 HPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCF--HGG-TCEATAG 1066
Score = 110 bits (265), Expect = 9e-24
Identities = 119/470 (25%), Positives = 177/470 (37%), Gaps = 78/470 (16%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C ++ GF+CIC PG+ G C D+DECR +P G+C++ G++ C C PGF
Sbjct: 528 CHDLLNGFQCICLPGFS----GTRCEEDIDECRSSP-CANGGQCQDQPGAFHCKCLPGFE 582
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR------PTATRGACVDVDEC 124
+VDEC +D G C++ G+F C+C +G+ P C C
Sbjct: 583 GPRCQ--TEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 640
Query: 125 EEQR-----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-GVSCQA------ 172
++Q+ +C +G P C C G + +C+ +GW G C+A
Sbjct: 641 KDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS---SCV-CDVGWTGPECEAELGGCI 696
Query: 173 ---CPAQGS-----ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
C G+ Y CP G + ++ C + P GSC GY C C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP-CLNGGSCNPSPGGYYCTC 755
Query: 225 DPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQL---- 277
P + C+ + + GG C N G+F+C+C +G R E +L+
Sbjct: 756 PPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 812
Query: 278 --CRDIDECEGETETH--YIESDYERGDIPPTFPTRTELASPCD-NGRCINTHGGFECEC 332
CR+ C+ + + Y G + PC N C+ T F C C
Sbjct: 813 SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQ--KPCPRNSHCLQTGPSFHCLC 870
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
G+ T C + C+ AA + C G G
Sbjct: 871 LQGW----TGPLC----------NLPLSSCQKAALSQGIDVSSLCHNG---GLCVDSGPS 913
Query: 393 XXXXXXKGFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G+ C+D V+ C S G TC+ Y C C PG
Sbjct: 914 YFCHCPPGF---QGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQCAPG 959
Score = 110 bits (264), Expect = 1e-23
Identities = 138/473 (29%), Positives = 189/473 (39%), Gaps = 89/473 (18%)
Query: 5 GMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCR----NT 57
G C G C N G F+C+C G EG C C PR C G C+
Sbjct: 203 GPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCP--PRGCSNGGTCQLMPEKD 256
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ + CLC PGF + D C + GG C + ++ C+C T T
Sbjct: 257 STFHLCLCPPGFIGPDCE--VNPDNCVSHQCQNGGTCQDGLDTYTCLCPE----TWTGWD 310
Query: 118 CV-DVDECEEQRV--CRNG-RCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSC 170
C DVDECE Q CRNG C N+ GSF C C+ G+ + + C+ G +C
Sbjct: 311 CSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG----SCENLEPGYRCICDP 226
GS ++ LCP G + + + C + P C HG S L C+C P
Sbjct: 371 --IDRVGS--FSCLCPPGRTGLLCHLE-DMCLSQP--C-HGDAQCSTNPLTGSTLCLCQP 422
Query: 227 GYHPDADGLC-RDIDECDMHQ---SYCA-GGQCRNTAGSFTCVCP---EGTRHEPE---- 274
GY + C +D+DEC M Q S C GG C NT GSF C+CP G+R E +
Sbjct: 423 GY---SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 479
Query: 275 -LQLCRDIDECEGETET-HYIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECE 331
Q C C T H + G + T ++PC ++ C + GF+C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV-ETNECASAPCLNHADCHDLLNGFQCI 538
Query: 332 CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
C G+ + +D R S GQC+ C C G
Sbjct: 539 CLPGF-SGTRCEEDIDECRSSPCAN--GGQCQDQPGAF----HCKCLPG----------- 580
Query: 392 XXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G C+ +VDEC LS G +C++ G++ C CP G T
Sbjct: 581 ------------FEGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFT 620
Score = 96.7 bits (230), Expect = 1e-19
Identities = 119/461 (25%), Positives = 169/461 (36%), Gaps = 71/461 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTC 63
C NG +C +C C PG+ EG C RDV+EC +P C +G C NT GS+ C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 220
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRC---VNSEGSFQ-CVCEAGYRPTATRGACV 119
LC G A C GG C + +F C+C G+ V
Sbjct: 221 LCPVGQEGPRCELRA--GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---V 275
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ D C + G C + ++ C C G+ S D C + C
Sbjct: 276 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ V C G + ++++C A A P +C + + C+C PG GL
Sbjct: 336 AGSFHCV-CVSGWGGTSCEENLDDCIAATCA-PGSTCIDRVGSFSCLCPPG----RTGLL 389
Query: 237 RDIDECDMHQSYCAGGQCRNT--AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
+++ + Q QC GS C+C G P +D+DEC
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPG-YSGPTCH--QDLDEC---------- 436
Query: 295 SDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLDN-- 348
++G SPC++ G C+NT G F C C GY +A CL
Sbjct: 437 LMAQQG------------PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPC 484
Query: 349 RRGS-CWRRVVDGQCEAAAPEL------LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GS C + C P L + EC + L GF
Sbjct: 485 HPGSTCLDLLATFHC-LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ G C D+DEC S+ GG C + G++ C C PG
Sbjct: 544 S---GTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKCLPG 580
Score = 90.6 bits (215), Expect = 1e-17
Identities = 127/462 (27%), Positives = 171/462 (37%), Gaps = 81/462 (17%)
Query: 42 CRDNPRVCRRG-RCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCV--- 95
C P C G C + + G TC C PGF C D C +C+ GG C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQALL 84
Query: 96 -------NSEG----SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH-NTPGSFR 143
+S SF C C G+ T R D C + GRCH G +
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 142
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--YAVL---CPEGPSKDNGGADI 198
C C+PG+T G C +L S C G L Y + CP G D+
Sbjct: 143 CSCMPGWT----GEQC---QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 195
Query: 199 NECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCR- 255
NEC PG CP G SC N ++C+C G +G ++ C+ GG C+
Sbjct: 196 NECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQL 251
Query: 256 ---NTAGSFTCVCPEG-----TRHEPE---LQLCRDIDECEG--ETETHYIESDYERGDI 302
+ C+CP G P+ C++ C+ +T T + D
Sbjct: 252 MPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 311
Query: 303 PPTF-PTRTELASPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGS 352
T+ C N G C N+ G F C C G+ + D A C +
Sbjct: 312 SEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG--ST 369
Query: 353 CWRRV--VDGQCEAAAPELLLRQECCC----SVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
C RV C LL E C G A S G++ G
Sbjct: 370 CIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS---G 426
Query: 407 ATC-RDVDECALSAE---LCA-GGTCVNTDGSYRCDCPPGLT 443
TC +D+DEC ++ + C GG+C+NT GS+ C CPPG T
Sbjct: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
Score = 88.6 bits (210), Expect = 4e-17
Identities = 90/353 (25%), Positives = 130/353 (36%), Gaps = 59/353 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C G+ C C GY G C ++ C P + G C + G Y C C P
Sbjct: 704 GTCYPQPSGYNCTCPTGYT----GPTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPS 758
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
T D C + GG CVN G+F C+C G++ G C +
Sbjct: 759 H--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--RPSCADS- 813
Query: 129 VCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
CRN C ++P RC C G+T +T + L + Q + LC +
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 872
Query: 188 G--------PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRD 238
G P A +++ V C +G C + P Y C C PG+ LC+D
Sbjct: 873 GWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ---GSLCQD 929
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
H + C C+N A TC+ +P LC+ +G+ + +++
Sbjct: 930 ------HVNPCESRPCQNGA---TCMA------QPSGYLCQCAPGYDGQNCSKELDACQ- 973
Query: 299 RGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLD 347
+ PC N G C GGF C C G+V + CLD
Sbjct: 974 --------------SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD 1012
Score = 73.3 bits (172), Expect = 2e-12
Identities = 70/264 (26%), Positives = 97/264 (36%), Gaps = 35/264 (13%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECR--------DNPRVCRRGR-CRNTA 58
N C F C+C G+ G LC + C+ D +C G C ++
Sbjct: 856 NSHCLQTGPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSG 911
Query: 59 GSYTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
SY C C PGF C D V+ C + G C+ + C C GY +
Sbjct: 912 PSYFCHCPPGFQ---GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDG---QNC 965
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACP 174
++D C+ Q +G C PG F C C PGF D CL AC
Sbjct: 966 SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPC-HPTGTAACH 1024
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENL--EP-GYRCICDPGYHP 230
+ + Y C G + +I+ C + P C H G+CE P G+ C C G+
Sbjct: 1025 SLANAFYC-QCLPGHTGQWCEVEIDPCHSQP--CFHGGTCEATAGSPLGFICHCPKGF-- 1079
Query: 231 DADGLCRDIDECDMHQSYCAGGQC 254
+ C H + GG C
Sbjct: 1080 EGPTCSHRAPSCGFHHCH-HGGLC 1102
Score = 62.5 bits (145), Expect = 3e-09
Identities = 78/270 (28%), Positives = 97/270 (35%), Gaps = 40/270 (14%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS---YTCLCEP 67
C ++ F C C PG+ G C ++D C P G C TAGS + C C
Sbjct: 1023 CHSLANAFYCQCLPGHT----GQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPK 1077
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNS-EGSF--QCVCEAGY------RPTATRGAC 118
GF + A C GG C+ S + F +C C +GY P A +G C
Sbjct: 1078 GFEGPTCSHRAP--SCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG-C 1134
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDG-RTCLGLKLGWGVSCQACP 174
C C PG FRC C PG G + C G + G G C
Sbjct: 1135 GPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRCQKPGAKGCEG-RSGDGACDAGCS 1192
Query: 175 AQGSELYAVLCPEG-PSKDNGGADINECTAV--PGACPHGSCENLE---PGYRCICDPGY 228
G C G P G + C + G C H C++ E GY C P
Sbjct: 1193 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQC-HPQCDSEECLFDGYDCETPPAC 1251
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTA 258
P D C D H +C G C NTA
Sbjct: 1252 TPAYDQYCHD----HFHNGHCEKG-C-NTA 1275
Score = 33.1 bits (72), Expect = 2.1
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPG 441
DG C +++D C ++ C GTC G + C CPPG
Sbjct: 961 DGQNCSKELDAC--QSQPCHNHGTCTPKPGGFHCACPPG 997
Score = 32.7 bits (71), Expect = 2.7
Identities = 14/38 (36%), Positives = 17/38 (44%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G TC + S GG+C + G Y C CPP T
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 128 bits (309), Expect = 4e-29
Identities = 135/476 (28%), Positives = 186/476 (39%), Gaps = 75/476 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRG-RCRNTAGS 60
NGG C +G+ + C+C E+ + DVDEC P CR G C+N+AGS
Sbjct: 287 NGGTCQDGL-----DTYTCLCP---ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C+C G+ T+ ++D+C A + G C++ GSF C+C G T C
Sbjct: 339 FHCVCVSGWGGTSCE--ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGLLCHL 392
Query: 121 VDECEEQRVCRNGRCHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLG-----WGVSC 170
D C Q + +C P GS C C PG+ T D CL + G G SC
Sbjct: 393 EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 452
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
P GS + LCP G + AD NEC + P P +C +L + C+C PG
Sbjct: 453 LNTP--GS--FNCLCPPGYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGLEG 507
Query: 231 DADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEG 286
LC +++ + + C C + F C+C P GTR E ++ CR G
Sbjct: 508 Q---LC-EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANG 563
Query: 287 ---ETETHYIESDYERGDIPPTFPTRTE--LASPCDNGR-CINTHGGFECECELGYV--- 337
+ + G P T + L+ PC G C++ G F C C G+
Sbjct: 564 GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQL 623
Query: 338 ---------LDATAQRCLDNR-RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
L Q C D + + +C DG A PE C C G S
Sbjct: 624 CEVPLCAPNLCQPKQICKDQKDKANCL--CPDGSPGCAPPE----DNCTCHHGHCQRSSC 677
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ G C +SA GGTC Y C CP G T
Sbjct: 678 VCDV--------GWT---GPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 722
Score = 120 bits (289), Expect = 1e-26
Identities = 115/419 (27%), Positives = 155/419 (36%), Gaps = 71/419 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
G C N G F C+C PGY G+ C D +EC P C G C + ++ CLC P
Sbjct: 450 GSCLNTPGSFNCLCPPGYT----GSRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPP 503
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
G + +ECA+ C + FQC+C G+ T D+DEC
Sbjct: 504 GLEGQLCE--VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE---DIDECRSS 558
Query: 128 RVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
G+C + PG+F C+CLPGF + CL G SC P + L
Sbjct: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA----FFCL 614
Query: 185 CPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCIC---DPGYHPDAD------G 234
CP G + ++ C P C P C++ + C+C PG P D G
Sbjct: 615 CPSGFTGQL--CEVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHG 670
Query: 235 LCR------DID----ECDMHQSYCA------GGQCRNTAGSFTCVCPEGTRH---EPEL 275
C+ D+ EC+ C GG C + C CP G E+
Sbjct: 671 HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
Query: 276 QLCRDIDECEGETETHYIESDYERGDIP----PTFPTRTE--LASPCDNG-RCINTHGGF 328
C C + Y P P T T+ +++PC NG C+N G F
Sbjct: 731 TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTF 789
Query: 329 ECECELGYVLDATAQRCLDNRRGSCWRRVVDGQC--EAAAPELLLRQECCCSVGLAWGS 385
C C +G+ RC R SC D C A + C C G GS
Sbjct: 790 SCLCAMGF----QGPRCEGKLRPSC----ADSPCRNRATCQDSPQGPRCLCPTGYTGGS 840
Score = 119 bits (287), Expect = 2e-26
Identities = 130/465 (27%), Positives = 183/465 (39%), Gaps = 62/465 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRR-GRCRNT--AGSYT 62
C G C + G F C+C PG G LC D C P C +C GS
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPG----RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTL 417
Query: 63 CLCEPGFA-PTAAGYCADVDECA----ADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRG 116
CLC+PG++ PT D+DEC S C+ GG C+N+ GSF C+C GY T +R
Sbjct: 418 CLCQPGYSGPTCH---QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSR- 471
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP-- 174
D +EC Q C + +F C C PG +G+ C ++ C + P
Sbjct: 472 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGL----EGQLC-EVETN---ECASAPCL 523
Query: 175 --AQGSEL---YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A +L + +C G S DI+EC + P A G C++ + C C PG+
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCA-NGGQCQDQPGAFHCKCLPGF- 581
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPEL-----QLCRDIDE 283
+ ++DEC + G C + G+F C+CP G T E+ LC+
Sbjct: 582 -EGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQI 639
Query: 284 CEGETE-THYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG--GFECECELGYVLDA 340
C+ + + + + D G PP T C C+ G G ECE ELG + A
Sbjct: 640 CKDQKDKANCLCPDGSPGCAPPE-DNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISA 698
Query: 341 TAQRCLDNRRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
C G+C+ + C P C S G
Sbjct: 699 P---CAHG--GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C+ + +SA GGTCVN G++ C C G
Sbjct: 754 TCP--PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
Score = 117 bits (281), Expect = 1e-25
Identities = 126/440 (28%), Positives = 174/440 (39%), Gaps = 51/440 (11%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCR-NTAGSYTCLCEPGFAPTAAGY 76
F C C PG+ E + D C P C +RGRC +G C C PG+
Sbjct: 101 FLCTCLPGFTG--ERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT---GEQ 153
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNG-R 134
C D C+A+ GG C+ + QC C G+ A DV+EC ++ C G
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS 210
Query: 135 CHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
CHNT GSF+C C G C G +CQ P + S + LCP P
Sbjct: 211 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP--PGF 268
Query: 192 DNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH-QSYC 249
++N V C + G+C++ Y C+C P D D+DEC+ +C
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC-PETWTGWD-CSEDVDECETQGPPHC 326
Query: 250 A-GGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
GG C+N+AGSF CVC GT E L C G T I+ + P
Sbjct: 327 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGST---CIDRVGSFSCLCP- 382
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
P RT L ++ C++ + +C + +T C G C
Sbjct: 383 -PGRTGLLCHLED-MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP--------TCHQD 432
Query: 366 APELLLRQE--CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELC 422
E L+ Q+ C G GS G+ G+ C D +EC LS
Sbjct: 433 LDECLMAQQGPSPCEHG---GSCLNTPGSFNCLCPPGYT---GSRCEADHNEC-LSQPCH 485
Query: 423 AGGTCVNTDGSYRCDCPPGL 442
G TC++ ++ C CPPGL
Sbjct: 486 PGSTCLDLLATFHCLCPPGL 505
Score = 111 bits (267), Expect = 5e-24
Identities = 104/354 (29%), Positives = 140/354 (39%), Gaps = 42/354 (11%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS 60
+ G C NG C GG+ C C P + G C+ D C P G C N G+
Sbjct: 734 HSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTDYCVSAP-CFNGGTCVNRPGT 788
Query: 61 YTCLCEPGF-APTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGAC 118
++CLC GF P G + ADS C+ C +S +C+C GY T G+C
Sbjct: 789 FSCLCAMGFQGPRCEG---KLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TGGSC 841
Query: 119 VD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSN-DGRTCLGLKLGWGVSCQACP 174
+D C ++ RN C T SF C CL G+T L N +C L G+ +
Sbjct: 842 QTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 901
Query: 175 AQG------SELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPG 227
G Y CP G +N C + P C +G +C GY C C PG
Sbjct: 902 HNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPG 959
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDEC 284
Y D +++D C + G C G F C CP G R E ++ C D C
Sbjct: 960 Y--DGQNCSKELDACQSQPCH-NHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD-QPC 1015
Query: 285 E--GETETHYIESDYERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELG 335
G H + + + +P E+ PC + C HGG CE G
Sbjct: 1016 HPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCF--HGG-TCEATAG 1066
Score = 110 bits (265), Expect = 9e-24
Identities = 119/470 (25%), Positives = 177/470 (37%), Gaps = 78/470 (16%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C ++ GF+CIC PG+ G C D+DECR +P G+C++ G++ C C PGF
Sbjct: 528 CHDLLNGFQCICLPGFS----GTRCEEDIDECRSSP-CANGGQCQDQPGAFHCKCLPGFE 582
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR------PTATRGACVDVDEC 124
+VDEC +D G C++ G+F C+C +G+ P C C
Sbjct: 583 GPRCQ--TEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 640
Query: 125 EEQR-----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-GVSCQA------ 172
++Q+ +C +G P C C G + +C+ +GW G C+A
Sbjct: 641 KDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS---SCV-CDVGWTGPECEAELGGCI 696
Query: 173 ---CPAQGS-----ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
C G+ Y CP G + ++ C + P GSC GY C C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP-CLNGGSCNPSPGGYYCTC 755
Query: 225 DPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQL---- 277
P + C+ + + GG C N G+F+C+C +G R E +L+
Sbjct: 756 PPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 812
Query: 278 --CRDIDECEGETETH--YIESDYERGDIPPTFPTRTELASPCD-NGRCINTHGGFECEC 332
CR+ C+ + + Y G + PC N C+ T F C C
Sbjct: 813 SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQ--KPCPRNSHCLQTGPSFHCLC 870
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
G+ T C + C+ AA + C G G
Sbjct: 871 LQGW----TGPLC----------NLPLSSCQKAALSQGIDVSSLCHNG---GLCVDSGPS 913
Query: 393 XXXXXXKGFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G+ C+D V+ C S G TC+ Y C C PG
Sbjct: 914 YFCHCPPGF---QGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQCAPG 959
Score = 110 bits (264), Expect = 1e-23
Identities = 138/473 (29%), Positives = 189/473 (39%), Gaps = 89/473 (18%)
Query: 5 GMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCR----NT 57
G C G C N G F+C+C G EG C C PR C G C+
Sbjct: 203 GPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCP--PRGCSNGGTCQLMPEKD 256
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ + CLC PGF + D C + GG C + ++ C+C T T
Sbjct: 257 STFHLCLCPPGFIGPDCE--VNPDNCVSHQCQNGGTCQDGLDTYTCLCPE----TWTGWD 310
Query: 118 CV-DVDECEEQRV--CRNG-RCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSC 170
C DVDECE Q CRNG C N+ GSF C C+ G+ + + C+ G +C
Sbjct: 311 CSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG----SCENLEPGYRCICDP 226
GS ++ LCP G + + + C + P C HG S L C+C P
Sbjct: 371 --IDRVGS--FSCLCPPGRTGLLCHLE-DMCLSQP--C-HGDAQCSTNPLTGSTLCLCQP 422
Query: 227 GYHPDADGLC-RDIDECDMHQ---SYCA-GGQCRNTAGSFTCVCP---EGTRHEPE---- 274
GY + C +D+DEC M Q S C GG C NT GSF C+CP G+R E +
Sbjct: 423 GY---SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 479
Query: 275 -LQLCRDIDECEGETET-HYIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECE 331
Q C C T H + G + T ++PC ++ C + GF+C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV-ETNECASAPCLNHADCHDLLNGFQCI 538
Query: 332 CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
C G+ + +D R S GQC+ C C G
Sbjct: 539 CLPGF-SGTRCEEDIDECRSSPCAN--GGQCQDQPGAF----HCKCLPG----------- 580
Query: 392 XXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G C+ +VDEC LS G +C++ G++ C CP G T
Sbjct: 581 ------------FEGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFT 620
Score = 96.7 bits (230), Expect = 1e-19
Identities = 119/461 (25%), Positives = 169/461 (36%), Gaps = 71/461 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTC 63
C NG +C +C C PG+ EG C RDV+EC +P C +G C NT GS+ C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 220
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRC---VNSEGSFQ-CVCEAGYRPTATRGACV 119
LC G A C GG C + +F C+C G+ V
Sbjct: 221 LCPVGQEGPRCELRA--GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---V 275
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ D C + G C + ++ C C G+ S D C + C
Sbjct: 276 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ V C G + ++++C A A P +C + + C+C PG GL
Sbjct: 336 AGSFHCV-CVSGWGGTSCEENLDDCIAATCA-PGSTCIDRVGSFSCLCPPG----RTGLL 389
Query: 237 RDIDECDMHQSYCAGGQCRNT--AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
+++ + Q QC GS C+C G P +D+DEC
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPG-YSGPTCH--QDLDEC---------- 436
Query: 295 SDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLDN-- 348
++G SPC++ G C+NT G F C C GY +A CL
Sbjct: 437 LMAQQG------------PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPC 484
Query: 349 RRGS-CWRRVVDGQCEAAAPEL------LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GS C + C P L + EC + L GF
Sbjct: 485 HPGSTCLDLLATFHC-LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ G C D+DEC S+ GG C + G++ C C PG
Sbjct: 544 S---GTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKCLPG 580
Score = 90.6 bits (215), Expect = 1e-17
Identities = 127/462 (27%), Positives = 171/462 (37%), Gaps = 81/462 (17%)
Query: 42 CRDNPRVCRRG-RCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCV--- 95
C P C G C + + G TC C PGF C D C +C+ GG C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQALL 84
Query: 96 -------NSEG----SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH-NTPGSFR 143
+S SF C C G+ T R D C + GRCH G +
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 142
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--YAVL---CPEGPSKDNGGADI 198
C C+PG+T G C +L S C G L Y + CP G D+
Sbjct: 143 CSCMPGWT----GEQC---QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 195
Query: 199 NECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCR- 255
NEC PG CP G SC N ++C+C G +G ++ C+ GG C+
Sbjct: 196 NECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQL 251
Query: 256 ---NTAGSFTCVCPEG-----TRHEPE---LQLCRDIDECEG--ETETHYIESDYERGDI 302
+ C+CP G P+ C++ C+ +T T + D
Sbjct: 252 MPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 311
Query: 303 PPTF-PTRTELASPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGS 352
T+ C N G C N+ G F C C G+ + D A C +
Sbjct: 312 SEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG--ST 369
Query: 353 CWRRV--VDGQCEAAAPELLLRQECCC----SVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
C RV C LL E C G A S G++ G
Sbjct: 370 CIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS---G 426
Query: 407 ATC-RDVDECALSAE---LCA-GGTCVNTDGSYRCDCPPGLT 443
TC +D+DEC ++ + C GG+C+NT GS+ C CPPG T
Sbjct: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
Score = 88.6 bits (210), Expect = 4e-17
Identities = 90/353 (25%), Positives = 130/353 (36%), Gaps = 59/353 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C G+ C C GY G C ++ C P + G C + G Y C C P
Sbjct: 704 GTCYPQPSGYNCTCPTGYT----GPTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPS 758
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
T D C + GG CVN G+F C+C G++ G C +
Sbjct: 759 H--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--RPSCADS- 813
Query: 129 VCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
CRN C ++P RC C G+T +T + L + Q + LC +
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 872
Query: 188 G--------PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRD 238
G P A +++ V C +G C + P Y C C PG+ LC+D
Sbjct: 873 GWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ---GSLCQD 929
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
H + C C+N A TC+ +P LC+ +G+ + +++
Sbjct: 930 ------HVNPCESRPCQNGA---TCMA------QPSGYLCQCAPGYDGQNCSKELDACQ- 973
Query: 299 RGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLD 347
+ PC N G C GGF C C G+V + CLD
Sbjct: 974 --------------SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD 1012
Score = 73.3 bits (172), Expect = 2e-12
Identities = 70/264 (26%), Positives = 97/264 (36%), Gaps = 35/264 (13%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECR--------DNPRVCRRGR-CRNTA 58
N C F C+C G+ G LC + C+ D +C G C ++
Sbjct: 856 NSHCLQTGPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSG 911
Query: 59 GSYTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
SY C C PGF C D V+ C + G C+ + C C GY +
Sbjct: 912 PSYFCHCPPGFQ---GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDG---QNC 965
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACP 174
++D C+ Q +G C PG F C C PGF D CL AC
Sbjct: 966 SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPC-HPTGTAACH 1024
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENL--EP-GYRCICDPGYHP 230
+ + Y C G + +I+ C + P C H G+CE P G+ C C G+
Sbjct: 1025 SLANAFYC-QCLPGHTGQWCEVEIDPCHSQP--CFHGGTCEATAGSPLGFICHCPKGF-- 1079
Query: 231 DADGLCRDIDECDMHQSYCAGGQC 254
+ C H + GG C
Sbjct: 1080 EGPTCSHRAPSCGFHHCH-HGGLC 1102
Score = 62.5 bits (145), Expect = 3e-09
Identities = 78/270 (28%), Positives = 97/270 (35%), Gaps = 40/270 (14%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS---YTCLCEP 67
C ++ F C C PG+ G C ++D C P G C TAGS + C C
Sbjct: 1023 CHSLANAFYCQCLPGHT----GQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPK 1077
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNS-EGSF--QCVCEAGY------RPTATRGAC 118
GF + A C GG C+ S + F +C C +GY P A +G C
Sbjct: 1078 GFEGPTCSHRAP--SCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG-C 1134
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDG-RTCLGLKLGWGVSCQACP 174
C C PG FRC C PG G + C G + G G C
Sbjct: 1135 GPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRCQKPGAKGCEG-RSGDGACDAGCS 1192
Query: 175 AQGSELYAVLCPEG-PSKDNGGADINECTAV--PGACPHGSCENLE---PGYRCICDPGY 228
G C G P G + C + G C H C++ E GY C P
Sbjct: 1193 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQC-HPQCDSEECLFDGYDCETPPAC 1251
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTA 258
P D C D H +C G C NTA
Sbjct: 1252 TPAYDQYCHD----HFHNGHCEKG-C-NTA 1275
Score = 33.1 bits (72), Expect = 2.1
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPG 441
DG C +++D C ++ C GTC G + C CPPG
Sbjct: 961 DGQNCSKELDAC--QSQPCHNHGTCTPKPGGFHCACPPG 997
Score = 32.7 bits (71), Expect = 2.7
Identities = 14/38 (36%), Positives = 17/38 (44%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G TC + S GG+C + G Y C CPP T
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 128 bits (309), Expect = 4e-29
Identities = 135/476 (28%), Positives = 186/476 (39%), Gaps = 75/476 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRG-RCRNTAGS 60
NGG C +G+ + C+C E+ + DVDEC P CR G C+N+AGS
Sbjct: 287 NGGTCQDGL-----DTYTCLCP---ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C+C G+ T+ ++D+C A + G C++ GSF C+C G T C
Sbjct: 339 FHCVCVSGWGGTSCE--ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGLLCHL 392
Query: 121 VDECEEQRVCRNGRCHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLG-----WGVSC 170
D C Q + +C P GS C C PG+ T D CL + G G SC
Sbjct: 393 EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 452
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
P GS + LCP G + AD NEC + P P +C +L + C+C PG
Sbjct: 453 LNTP--GS--FNCLCPPGYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGLEG 507
Query: 231 DADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEG 286
LC +++ + + C C + F C+C P GTR E ++ CR G
Sbjct: 508 Q---LC-EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANG 563
Query: 287 ---ETETHYIESDYERGDIPPTFPTRTE--LASPCDNGR-CINTHGGFECECELGYV--- 337
+ + G P T + L+ PC G C++ G F C C G+
Sbjct: 564 GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQL 623
Query: 338 ---------LDATAQRCLDNR-RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
L Q C D + + +C DG A PE C C G S
Sbjct: 624 CEVPLCAPNLCQPKQICKDQKDKANCL--CPDGSPGCAPPE----DNCTCHHGHCQRSSC 677
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ G C +SA GGTC Y C CP G T
Sbjct: 678 VCDV--------GWT---GPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 722
Score = 119 bits (287), Expect = 2e-26
Identities = 130/465 (27%), Positives = 183/465 (39%), Gaps = 62/465 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRR-GRCRNT--AGSYT 62
C G C + G F C+C PG G LC D C P C +C GS
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPG----RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTL 417
Query: 63 CLCEPGFA-PTAAGYCADVDECA----ADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRG 116
CLC+PG++ PT D+DEC S C+ GG C+N+ GSF C+C GY T +R
Sbjct: 418 CLCQPGYSGPTCH---QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSR- 471
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP-- 174
D +EC Q C + +F C C PG +G+ C ++ C + P
Sbjct: 472 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGL----EGQLC-EVETN---ECASAPCL 523
Query: 175 --AQGSEL---YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A +L + +C G S DI+EC + P A G C++ + C C PG+
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCA-NGGQCQDQPGAFHCKCLPGF- 581
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPEL-----QLCRDIDE 283
+ ++DEC + G C + G+F C+CP G T E+ LC+
Sbjct: 582 -EGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQI 639
Query: 284 CEGETE-THYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG--GFECECELGYVLDA 340
C+ + + + + D G PP T C C+ G G ECE ELG + A
Sbjct: 640 CKDQKDKANCLCPDGSPGCAPPE-DNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISA 698
Query: 341 TAQRCLDNRRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
C G+C+ + C P C S G
Sbjct: 699 P---CAHG--GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C+ + +SA GGTCVN G++ C C G
Sbjct: 754 TCP--PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
Score = 117 bits (281), Expect = 1e-25
Identities = 126/440 (28%), Positives = 174/440 (39%), Gaps = 51/440 (11%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCR-NTAGSYTCLCEPGFAPTAAGY 76
F C C PG+ E + D C P C +RGRC +G C C PG+
Sbjct: 101 FLCTCLPGFTG--ERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT---GEQ 153
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNG-R 134
C D C+A+ GG C+ + QC C G+ A DV+EC ++ C G
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS 210
Query: 135 CHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
CHNT GSF+C C G C G +CQ P + S + LCP P
Sbjct: 211 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP--PGF 268
Query: 192 DNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH-QSYC 249
++N V C + G+C++ Y C+C P D D+DEC+ +C
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC-PETWTGWD-CSEDVDECETQGPPHC 326
Query: 250 A-GGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
GG C+N+AGSF CVC GT E L C G T I+ + P
Sbjct: 327 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGST---CIDRVGSFSCLCP- 382
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
P RT L ++ C++ + +C + +T C G C
Sbjct: 383 -PGRTGLLCHLED-MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP--------TCHQD 432
Query: 366 APELLLRQE--CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELC 422
E L+ Q+ C G GS G+ G+ C D +EC LS
Sbjct: 433 LDECLMAQQGPSPCEHG---GSCLNTPGSFNCLCPPGYT---GSRCEADHNEC-LSQPCH 485
Query: 423 AGGTCVNTDGSYRCDCPPGL 442
G TC++ ++ C CPPGL
Sbjct: 486 PGSTCLDLLATFHCLCPPGL 505
Score = 117 bits (281), Expect = 1e-25
Identities = 107/385 (27%), Positives = 146/385 (37%), Gaps = 65/385 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
G C N G F C+C PGY G+ C D +EC P C G C + ++ CLC P
Sbjct: 450 GSCLNTPGSFNCLCPPGYT----GSRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPP 503
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
G + +ECA+ C + FQC+C G+ T D+DEC
Sbjct: 504 GLEGQLCE--VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE---DIDECRSS 558
Query: 128 RVCRNGRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
G+C + PG+F C+CLPGF + CL G SC P + L
Sbjct: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPG----AFFCL 614
Query: 185 CPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCIC---DPGYHPDAD------G 234
CP G + ++ C P C P C++ + C+C PG P D G
Sbjct: 615 CPSGFTGQL--CEVPLC--APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHG 670
Query: 235 LCR------DI----DECDMHQSYCA------GGQCRNTAGSFTCVCP---EGTRHEPEL 275
C+ D+ EC+ C GG C + C CP G E+
Sbjct: 671 HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
Query: 276 QLCRDIDECEGETETHYIESDYERGDIP----PTFPTRTE--LASPCDN-GRCINTHGGF 328
C C + Y P P T T+ +++PC N G C+N G F
Sbjct: 731 TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTF 789
Query: 329 ECECELGYVLDATAQRCLDNRRGSC 353
C C +G+ RC R SC
Sbjct: 790 SCLCAMGF----QGPRCEGKLRPSC 810
Score = 110 bits (264), Expect = 1e-23
Identities = 138/473 (29%), Positives = 189/473 (39%), Gaps = 89/473 (18%)
Query: 5 GMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCR----NT 57
G C G C N G F+C+C G EG C C PR C G C+
Sbjct: 203 GPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCP--PRGCSNGGTCQLMPEKD 256
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ + CLC PGF + D C + GG C + ++ C+C T T
Sbjct: 257 STFHLCLCPPGFIGPDCE--VNPDNCVSHQCQNGGTCQDGLDTYTCLCPE----TWTGWD 310
Query: 118 CV-DVDECEEQRV--CRNG-RCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSC 170
C DVDECE Q CRNG C N+ GSF C C+ G+ + + C+ G +C
Sbjct: 311 CSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG----SCENLEPGYRCICDP 226
GS ++ LCP G + + + C + P C HG S L C+C P
Sbjct: 371 --IDRVGS--FSCLCPPGRTGLLCHLE-DMCLSQP--C-HGDAQCSTNPLTGSTLCLCQP 422
Query: 227 GYHPDADGLC-RDIDECDMHQ---SYCA-GGQCRNTAGSFTCVCP---EGTRHEPE---- 274
GY + C +D+DEC M Q S C GG C NT GSF C+CP G+R E +
Sbjct: 423 GY---SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 479
Query: 275 -LQLCRDIDECEGETET-HYIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECE 331
Q C C T H + G + T ++PC ++ C + GF+C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV-ETNECASAPCLNHADCHDLLNGFQCI 538
Query: 332 CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
C G+ + +D R S GQC+ C C G
Sbjct: 539 CLPGF-SGTRCEEDIDECRSSPCAN--GGQCQDQPGAF----HCKCLPG----------- 580
Query: 392 XXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G C+ +VDEC LS G +C++ G++ C CP G T
Sbjct: 581 ------------FEGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFT 620
Score = 109 bits (263), Expect = 1e-23
Identities = 119/470 (25%), Positives = 177/470 (37%), Gaps = 78/470 (16%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C ++ GF+CIC PG+ G C D+DECR +P G+C++ G++ C C PGF
Sbjct: 528 CHDLLNGFQCICLPGFS----GTRCEEDIDECRSSP-CANGGQCQDQPGAFHCKCLPGFE 582
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR------PTATRGACVDVDEC 124
+VDEC +D G C++ G+F C+C +G+ P C C
Sbjct: 583 GPRCQ--TEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 640
Query: 125 EEQR-----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-GVSCQA------ 172
++Q+ +C +G P C C G + +C+ +GW G C+A
Sbjct: 641 KDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS---SCV-CDVGWTGPECEAELGGCI 696
Query: 173 ---CPAQGS-----ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
C G+ Y CP G + ++ C + P GSC GY C C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP-CLNGGSCNPSPGGYYCTC 755
Query: 225 DPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQL---- 277
P + C+ + + GG C N G+F+C+C +G R E +L+
Sbjct: 756 PPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 812
Query: 278 --CRDIDECEGETETH--YIESDYERGDIPPTFPTRTELASPCD-NGRCINTHGGFECEC 332
CR+ C+ + + Y G + PC N C+ T F C C
Sbjct: 813 SPCRNRATCQDSPQGPRCLCPTVYTGGSCQTLMDLCAQ--KPCPRNSHCLQTGPSFHCLC 870
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
G+ T C + C+ AA + C G G
Sbjct: 871 LQGW----TGPLC----------NLPLSSCQKAALSQGIDVSSLCHNG---GLCVDSGPS 913
Query: 393 XXXXXXKGFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G+ C+D V+ C S G TC+ Y C C PG
Sbjct: 914 YFCHCPPGF---QGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQCAPG 959
Score = 107 bits (258), Expect = 6e-23
Identities = 103/354 (29%), Positives = 139/354 (39%), Gaps = 42/354 (11%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS 60
+ G C NG C GG+ C C P + G C+ D C P G C N G+
Sbjct: 734 HSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTDYCVSAP-CFNGGTCVNRPGT 788
Query: 61 YTCLCEPGF-APTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGAC 118
++CLC GF P G + ADS C+ C +S +C+C Y T G+C
Sbjct: 789 FSCLCAMGFQGPRCEG---KLRPSCADSPCRNRATCQDSPQGPRCLCPTVY----TGGSC 841
Query: 119 VD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSN-DGRTCLGLKLGWGVSCQACP 174
+D C ++ RN C T SF C CL G+T L N +C L G+ +
Sbjct: 842 QTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 901
Query: 175 AQG------SELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPG 227
G Y CP G +N C + P C +G +C GY C C PG
Sbjct: 902 HNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPG 959
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDEC 284
Y D +++D C + G C G F C CP G R E ++ C D C
Sbjct: 960 Y--DGQNCSKELDACQSQPCH-NHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD-QPC 1015
Query: 285 E--GETETHYIESDYERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELG 335
G H + + + +P E+ PC + C HGG CE G
Sbjct: 1016 HPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCF--HGG-TCEATAG 1066
Score = 96.7 bits (230), Expect = 1e-19
Identities = 119/461 (25%), Positives = 169/461 (36%), Gaps = 71/461 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTC 63
C NG +C +C C PG+ EG C RDV+EC +P C +G C NT GS+ C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 220
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRC---VNSEGSFQ-CVCEAGYRPTATRGACV 119
LC G A C GG C + +F C+C G+ V
Sbjct: 221 LCPVGQEGPRCELRA--GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---V 275
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ D C + G C + ++ C C G+ S D C + C
Sbjct: 276 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ V C G + ++++C A A P +C + + C+C PG GL
Sbjct: 336 AGSFHCV-CVSGWGGTSCEENLDDCIAATCA-PGSTCIDRVGSFSCLCPPG----RTGLL 389
Query: 237 RDIDECDMHQSYCAGGQCRNT--AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
+++ + Q QC GS C+C G P +D+DEC
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPG-YSGPTCH--QDLDEC---------- 436
Query: 295 SDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLDN-- 348
++G SPC++ G C+NT G F C C GY +A CL
Sbjct: 437 LMAQQG------------PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPC 484
Query: 349 RRGS-CWRRVVDGQCEAAAPEL------LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GS C + C P L + EC + L GF
Sbjct: 485 HPGSTCLDLLATFHC-LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ G C D+DEC S+ GG C + G++ C C PG
Sbjct: 544 S---GTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKCLPG 580
Score = 90.6 bits (215), Expect = 1e-17
Identities = 127/462 (27%), Positives = 171/462 (37%), Gaps = 81/462 (17%)
Query: 42 CRDNPRVCRRG-RCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCV--- 95
C P C G C + + G TC C PGF C D C +C+ GG C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQALL 84
Query: 96 -------NSEG----SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH-NTPGSFR 143
+S SF C C G+ T R D C + GRCH G +
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 142
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--YAVL---CPEGPSKDNGGADI 198
C C+PG+T G C +L S C G L Y + CP G D+
Sbjct: 143 CSCMPGWT----GEQC---QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 195
Query: 199 NECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCR- 255
NEC PG CP G SC N ++C+C G +G ++ C+ GG C+
Sbjct: 196 NECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQL 251
Query: 256 ---NTAGSFTCVCPEG-----TRHEPE---LQLCRDIDECEG--ETETHYIESDYERGDI 302
+ C+CP G P+ C++ C+ +T T + D
Sbjct: 252 MPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 311
Query: 303 PPTF-PTRTELASPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGS 352
T+ C N G C N+ G F C C G+ + D A C +
Sbjct: 312 SEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG--ST 369
Query: 353 CWRRV--VDGQCEAAAPELLLRQECCC----SVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
C RV C LL E C G A S G++ G
Sbjct: 370 CIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS---G 426
Query: 407 ATC-RDVDECALSAE---LCA-GGTCVNTDGSYRCDCPPGLT 443
TC +D+DEC ++ + C GG+C+NT GS+ C CPPG T
Sbjct: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
Score = 85.0 bits (201), Expect = 5e-16
Identities = 89/353 (25%), Positives = 128/353 (36%), Gaps = 59/353 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C G+ C C GY G C ++ C P + G C + G Y C C P
Sbjct: 704 GTCYPQPSGYNCTCPTGYT----GPTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPS 758
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
T D C + GG CVN G+F C+C G++ G C +
Sbjct: 759 H--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--RPSCADS- 813
Query: 129 VCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
CRN C ++P RC C P +T + L + Q + LC +
Sbjct: 814 PCRNRATCQDSPQGPRCLC-PTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 872
Query: 188 G--------PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRD 238
G P A +++ V C +G C + P Y C C PG+ LC+D
Sbjct: 873 GWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ---GSLCQD 929
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
H + C C+N A TC+ +P LC+ +G+ + +++
Sbjct: 930 ------HVNPCESRPCQNGA---TCMA------QPSGYLCQCAPGYDGQNCSKELDACQ- 973
Query: 299 RGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLD 347
+ PC N G C GGF C C G+V + CLD
Sbjct: 974 --------------SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD 1012
Score = 73.3 bits (172), Expect = 2e-12
Identities = 70/264 (26%), Positives = 97/264 (36%), Gaps = 35/264 (13%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECR--------DNPRVCRRGR-CRNTA 58
N C F C+C G+ G LC + C+ D +C G C ++
Sbjct: 856 NSHCLQTGPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSG 911
Query: 59 GSYTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
SY C C PGF C D V+ C + G C+ + C C GY +
Sbjct: 912 PSYFCHCPPGFQ---GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDG---QNC 965
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACP 174
++D C+ Q +G C PG F C C PGF D CL AC
Sbjct: 966 SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPC-HPTGTAACH 1024
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENL--EP-GYRCICDPGYHP 230
+ + Y C G + +I+ C + P C H G+CE P G+ C C G+
Sbjct: 1025 SLANAFYC-QCLPGHTGQWCEVEIDPCHSQP--CFHGGTCEATAGSPLGFICHCPKGF-- 1079
Query: 231 DADGLCRDIDECDMHQSYCAGGQC 254
+ C H + GG C
Sbjct: 1080 EGPTCSHRAPSCGFHHCH-HGGLC 1102
Score = 62.5 bits (145), Expect = 3e-09
Identities = 78/270 (28%), Positives = 97/270 (35%), Gaps = 40/270 (14%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS---YTCLCEP 67
C ++ F C C PG+ G C ++D C P G C TAGS + C C
Sbjct: 1023 CHSLANAFYCQCLPGHT----GQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPK 1077
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNS-EGSF--QCVCEAGY------RPTATRGAC 118
GF + A C GG C+ S + F +C C +GY P A +G C
Sbjct: 1078 GFEGPTCSHRAP--SCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG-C 1134
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDG-RTCLGLKLGWGVSCQACP 174
C C PG FRC C PG G + C G + G G C
Sbjct: 1135 GPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRCQKPGAKGCEG-RSGDGACDAGCS 1192
Query: 175 AQGSELYAVLCPEG-PSKDNGGADINECTAV--PGACPHGSCENLE---PGYRCICDPGY 228
G C G P G + C + G C H C++ E GY C P
Sbjct: 1193 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQC-HPQCDSEECLFDGYDCETPPAC 1251
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTA 258
P D C D H +C G C NTA
Sbjct: 1252 TPAYDQYCHD----HFHNGHCEKG-C-NTA 1275
Score = 33.1 bits (72), Expect = 2.1
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPG 441
DG C +++D C ++ C GTC G + C CPPG
Sbjct: 961 DGQNCSKELDAC--QSQPCHNHGTCTPKPGGFHCACPPG 997
Score = 32.7 bits (71), Expect = 2.7
Identities = 14/38 (36%), Positives = 17/38 (44%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G TC + S GG+C + G Y C CPP T
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 128 bits (309), Expect = 4e-29
Identities = 135/476 (28%), Positives = 186/476 (39%), Gaps = 75/476 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRG-RCRNTAGS 60
NGG C +G+ + C+C E+ + DVDEC P CR G C+N+AGS
Sbjct: 287 NGGTCQDGL-----DTYTCLCP---ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C+C G+ T+ ++D+C A + G C++ GSF C+C G T C
Sbjct: 339 FHCVCVSGWGGTSCE--ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGLLCHL 392
Query: 121 VDECEEQRVCRNGRCHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLG-----WGVSC 170
D C Q + +C P GS C C PG+ T D CL + G G SC
Sbjct: 393 EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 452
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
P GS + LCP G + AD NEC + P P +C +L + C+C PG
Sbjct: 453 LNTP--GS--FNCLCPPGYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGLEG 507
Query: 231 DADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEG 286
LC +++ + + C C + F C+C P GTR E ++ CR G
Sbjct: 508 Q---LC-EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANG 563
Query: 287 ---ETETHYIESDYERGDIPPTFPTRTE--LASPCDNGR-CINTHGGFECECELGYV--- 337
+ + G P T + L+ PC G C++ G F C C G+
Sbjct: 564 GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQL 623
Query: 338 ---------LDATAQRCLDNR-RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
L Q C D + + +C DG A PE C C G S
Sbjct: 624 CEVPLCAPNLCQPKQICKDQKDKANCL--CPDGSPGCAPPE----DNCTCHHGHCQRSSC 677
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ G C +SA GGTC Y C CP G T
Sbjct: 678 VCDV--------GWT---GPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 722
Score = 119 bits (287), Expect = 2e-26
Identities = 130/465 (27%), Positives = 183/465 (39%), Gaps = 62/465 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRR-GRCRNT--AGSYT 62
C G C + G F C+C PG G LC D C P C +C GS
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPG----RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTL 417
Query: 63 CLCEPGFA-PTAAGYCADVDECA----ADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRG 116
CLC+PG++ PT D+DEC S C+ GG C+N+ GSF C+C GY T +R
Sbjct: 418 CLCQPGYSGPTCH---QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSR- 471
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP-- 174
D +EC Q C + +F C C PG +G+ C ++ C + P
Sbjct: 472 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGL----EGQLC-EVETN---ECASAPCL 523
Query: 175 --AQGSEL---YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A +L + +C G S DI+EC + P A G C++ + C C PG+
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCA-NGGQCQDQPGAFHCKCLPGF- 581
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPEL-----QLCRDIDE 283
+ ++DEC + G C + G+F C+CP G T E+ LC+
Sbjct: 582 -EGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQI 639
Query: 284 CEGETE-THYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG--GFECECELGYVLDA 340
C+ + + + + D G PP T C C+ G G ECE ELG + A
Sbjct: 640 CKDQKDKANCLCPDGSPGCAPPE-DNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISA 698
Query: 341 TAQRCLDNRRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
C G+C+ + C P C S G
Sbjct: 699 P---CAHG--GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C+ + +SA GGTCVN G++ C C G
Sbjct: 754 TCP--PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
Score = 117 bits (281), Expect = 1e-25
Identities = 126/440 (28%), Positives = 174/440 (39%), Gaps = 51/440 (11%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCR-NTAGSYTCLCEPGFAPTAAGY 76
F C C PG+ E + D C P C +RGRC +G C C PG+
Sbjct: 101 FLCTCLPGFTG--ERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT---GEQ 153
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNG-R 134
C D C+A+ GG C+ + QC C G+ A DV+EC ++ C G
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS 210
Query: 135 CHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
CHNT GSF+C C G C G +CQ P + S + LCP P
Sbjct: 211 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP--PGF 268
Query: 192 DNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH-QSYC 249
++N V C + G+C++ Y C+C P D D+DEC+ +C
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC-PETWTGWD-CSEDVDECETQGPPHC 326
Query: 250 A-GGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
GG C+N+AGSF CVC GT E L C G T I+ + P
Sbjct: 327 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGST---CIDRVGSFSCLCP- 382
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
P RT L ++ C++ + +C + +T C G C
Sbjct: 383 -PGRTGLLCHLED-MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP--------TCHQD 432
Query: 366 APELLLRQE--CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELC 422
E L+ Q+ C G GS G+ G+ C D +EC LS
Sbjct: 433 LDECLMAQQGPSPCEHG---GSCLNTPGSFNCLCPPGYT---GSRCEADHNEC-LSQPCH 485
Query: 423 AGGTCVNTDGSYRCDCPPGL 442
G TC++ ++ C CPPGL
Sbjct: 486 PGSTCLDLLATFHCLCPPGL 505
Score = 117 bits (281), Expect = 1e-25
Identities = 107/385 (27%), Positives = 146/385 (37%), Gaps = 65/385 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
G C N G F C+C PGY G+ C D +EC P C G C + ++ CLC P
Sbjct: 450 GSCLNTPGSFNCLCPPGYT----GSRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPP 503
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
G + +ECA+ C + FQC+C G+ T D+DEC
Sbjct: 504 GLEGQLCE--VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE---DIDECRSS 558
Query: 128 RVCRNGRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
G+C + PG+F C+CLPGF + CL G SC P + L
Sbjct: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPG----AFFCL 614
Query: 185 CPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCIC---DPGYHPDAD------G 234
CP G + ++ C P C P C++ + C+C PG P D G
Sbjct: 615 CPSGFTGQL--CEVPLC--APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHG 670
Query: 235 LCR------DI----DECDMHQSYCA------GGQCRNTAGSFTCVCP---EGTRHEPEL 275
C+ D+ EC+ C GG C + C CP G E+
Sbjct: 671 HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
Query: 276 QLCRDIDECEGETETHYIESDYERGDIP----PTFPTRTE--LASPCDN-GRCINTHGGF 328
C C + Y P P T T+ +++PC N G C+N G F
Sbjct: 731 TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTF 789
Query: 329 ECECELGYVLDATAQRCLDNRRGSC 353
C C +G+ RC R SC
Sbjct: 790 SCLCAMGF----QGPRCEGKLRPSC 810
Score = 110 bits (264), Expect = 1e-23
Identities = 138/473 (29%), Positives = 189/473 (39%), Gaps = 89/473 (18%)
Query: 5 GMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCR----NT 57
G C G C N G F+C+C G EG C C PR C G C+
Sbjct: 203 GPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCP--PRGCSNGGTCQLMPEKD 256
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ + CLC PGF + D C + GG C + ++ C+C T T
Sbjct: 257 STFHLCLCPPGFIGPDCE--VNPDNCVSHQCQNGGTCQDGLDTYTCLCPE----TWTGWD 310
Query: 118 CV-DVDECEEQRV--CRNG-RCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSC 170
C DVDECE Q CRNG C N+ GSF C C+ G+ + + C+ G +C
Sbjct: 311 CSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG----SCENLEPGYRCICDP 226
GS ++ LCP G + + + C + P C HG S L C+C P
Sbjct: 371 --IDRVGS--FSCLCPPGRTGLLCHLE-DMCLSQP--C-HGDAQCSTNPLTGSTLCLCQP 422
Query: 227 GYHPDADGLC-RDIDECDMHQ---SYCA-GGQCRNTAGSFTCVCP---EGTRHEPE---- 274
GY + C +D+DEC M Q S C GG C NT GSF C+CP G+R E +
Sbjct: 423 GY---SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 479
Query: 275 -LQLCRDIDECEGETET-HYIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECE 331
Q C C T H + G + T ++PC ++ C + GF+C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV-ETNECASAPCLNHADCHDLLNGFQCI 538
Query: 332 CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
C G+ + +D R S GQC+ C C G
Sbjct: 539 CLPGF-SGTRCEEDIDECRSSPCAN--GGQCQDQPGAF----HCKCLPG----------- 580
Query: 392 XXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G C+ +VDEC LS G +C++ G++ C CP G T
Sbjct: 581 ------------FEGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFT 620
Score = 109 bits (263), Expect = 1e-23
Identities = 119/470 (25%), Positives = 177/470 (37%), Gaps = 78/470 (16%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C ++ GF+CIC PG+ G C D+DECR +P G+C++ G++ C C PGF
Sbjct: 528 CHDLLNGFQCICLPGFS----GTRCEEDIDECRSSP-CANGGQCQDQPGAFHCKCLPGFE 582
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR------PTATRGACVDVDEC 124
+VDEC +D G C++ G+F C+C +G+ P C C
Sbjct: 583 GPRCQ--TEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 640
Query: 125 EEQR-----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-GVSCQA------ 172
++Q+ +C +G P C C G + +C+ +GW G C+A
Sbjct: 641 KDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS---SCV-CDVGWTGPECEAELGGCI 696
Query: 173 ---CPAQGS-----ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
C G+ Y CP G + ++ C + P GSC GY C C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP-CLNGGSCNPSPGGYYCTC 755
Query: 225 DPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQL---- 277
P + C+ + + GG C N G+F+C+C +G R E +L+
Sbjct: 756 PPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 812
Query: 278 --CRDIDECEGETETH--YIESDYERGDIPPTFPTRTELASPCD-NGRCINTHGGFECEC 332
CR+ C+ + + Y G + PC N C+ T F C C
Sbjct: 813 SPCRNRATCQDSPQGPRCLCPTVYTGGSCQTLMDLCAQ--KPCPRNSHCLQTGPSFHCLC 870
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
G+ T C + C+ AA + C G G
Sbjct: 871 LQGW----TGPLC----------NLPLSSCQKAALSQGIDVSSLCHNG---GLCVDSGPS 913
Query: 393 XXXXXXKGFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G+ C+D V+ C S G TC+ Y C C PG
Sbjct: 914 YFCHCPPGF---QGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQCAPG 959
Score = 107 bits (258), Expect = 6e-23
Identities = 103/354 (29%), Positives = 139/354 (39%), Gaps = 42/354 (11%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS 60
+ G C NG C GG+ C C P + G C+ D C P G C N G+
Sbjct: 734 HSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTDYCVSAP-CFNGGTCVNRPGT 788
Query: 61 YTCLCEPGF-APTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGAC 118
++CLC GF P G + ADS C+ C +S +C+C Y T G+C
Sbjct: 789 FSCLCAMGFQGPRCEG---KLRPSCADSPCRNRATCQDSPQGPRCLCPTVY----TGGSC 841
Query: 119 VD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSN-DGRTCLGLKLGWGVSCQACP 174
+D C ++ RN C T SF C CL G+T L N +C L G+ +
Sbjct: 842 QTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 901
Query: 175 AQG------SELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPG 227
G Y CP G +N C + P C +G +C GY C C PG
Sbjct: 902 HNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPG 959
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDEC 284
Y D +++D C + G C G F C CP G R E ++ C D C
Sbjct: 960 Y--DGQNCSKELDACQSQPCH-NHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD-QPC 1015
Query: 285 E--GETETHYIESDYERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELG 335
G H + + + +P E+ PC + C HGG CE G
Sbjct: 1016 HPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCF--HGG-TCEATAG 1066
Score = 96.7 bits (230), Expect = 1e-19
Identities = 119/461 (25%), Positives = 169/461 (36%), Gaps = 71/461 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTC 63
C NG +C +C C PG+ EG C RDV+EC +P C +G C NT GS+ C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 220
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRC---VNSEGSFQ-CVCEAGYRPTATRGACV 119
LC G A C GG C + +F C+C G+ V
Sbjct: 221 LCPVGQEGPRCELRA--GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---V 275
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ D C + G C + ++ C C G+ S D C + C
Sbjct: 276 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ V C G + ++++C A A P +C + + C+C PG GL
Sbjct: 336 AGSFHCV-CVSGWGGTSCEENLDDCIAATCA-PGSTCIDRVGSFSCLCPPG----RTGLL 389
Query: 237 RDIDECDMHQSYCAGGQCRNT--AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
+++ + Q QC GS C+C G P +D+DEC
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPG-YSGPTCH--QDLDEC---------- 436
Query: 295 SDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLDN-- 348
++G SPC++ G C+NT G F C C GY +A CL
Sbjct: 437 LMAQQG------------PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPC 484
Query: 349 RRGS-CWRRVVDGQCEAAAPEL------LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GS C + C P L + EC + L GF
Sbjct: 485 HPGSTCLDLLATFHC-LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ G C D+DEC S+ GG C + G++ C C PG
Sbjct: 544 S---GTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKCLPG 580
Score = 90.6 bits (215), Expect = 1e-17
Identities = 127/462 (27%), Positives = 171/462 (37%), Gaps = 81/462 (17%)
Query: 42 CRDNPRVCRRG-RCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCV--- 95
C P C G C + + G TC C PGF C D C +C+ GG C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQALL 84
Query: 96 -------NSEG----SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH-NTPGSFR 143
+S SF C C G+ T R D C + GRCH G +
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 142
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--YAVL---CPEGPSKDNGGADI 198
C C+PG+T G C +L S C G L Y + CP G D+
Sbjct: 143 CSCMPGWT----GEQC---QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 195
Query: 199 NECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCR- 255
NEC PG CP G SC N ++C+C G +G ++ C+ GG C+
Sbjct: 196 NECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQL 251
Query: 256 ---NTAGSFTCVCPEG-----TRHEPE---LQLCRDIDECEG--ETETHYIESDYERGDI 302
+ C+CP G P+ C++ C+ +T T + D
Sbjct: 252 MPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 311
Query: 303 PPTF-PTRTELASPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGS 352
T+ C N G C N+ G F C C G+ + D A C +
Sbjct: 312 SEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG--ST 369
Query: 353 CWRRV--VDGQCEAAAPELLLRQECCC----SVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
C RV C LL E C G A S G++ G
Sbjct: 370 CIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS---G 426
Query: 407 ATC-RDVDECALSAE---LCA-GGTCVNTDGSYRCDCPPGLT 443
TC +D+DEC ++ + C GG+C+NT GS+ C CPPG T
Sbjct: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
Score = 85.0 bits (201), Expect = 5e-16
Identities = 89/353 (25%), Positives = 128/353 (36%), Gaps = 59/353 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C G+ C C GY G C ++ C P + G C + G Y C C P
Sbjct: 704 GTCYPQPSGYNCTCPTGYT----GPTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPS 758
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
T D C + GG CVN G+F C+C G++ G C +
Sbjct: 759 H--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--RPSCADS- 813
Query: 129 VCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
CRN C ++P RC C P +T + L + Q + LC +
Sbjct: 814 PCRNRATCQDSPQGPRCLC-PTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 872
Query: 188 G--------PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRD 238
G P A +++ V C +G C + P Y C C PG+ LC+D
Sbjct: 873 GWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ---GSLCQD 929
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
H + C C+N A TC+ +P LC+ +G+ + +++
Sbjct: 930 ------HVNPCESRPCQNGA---TCMA------QPSGYLCQCAPGYDGQNCSKELDACQ- 973
Query: 299 RGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLD 347
+ PC N G C GGF C C G+V + CLD
Sbjct: 974 --------------SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD 1012
Score = 73.3 bits (172), Expect = 2e-12
Identities = 70/264 (26%), Positives = 97/264 (36%), Gaps = 35/264 (13%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECR--------DNPRVCRRGR-CRNTA 58
N C F C+C G+ G LC + C+ D +C G C ++
Sbjct: 856 NSHCLQTGPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSG 911
Query: 59 GSYTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
SY C C PGF C D V+ C + G C+ + C C GY +
Sbjct: 912 PSYFCHCPPGFQ---GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDG---QNC 965
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACP 174
++D C+ Q +G C PG F C C PGF D CL AC
Sbjct: 966 SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPC-HPTGTAACH 1024
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENL--EP-GYRCICDPGYHP 230
+ + Y C G + +I+ C + P C H G+CE P G+ C C G+
Sbjct: 1025 SLANAFYC-QCLPGHTGQWCEVEIDPCHSQP--CFHGGTCEATAGSPLGFICHCPKGF-- 1079
Query: 231 DADGLCRDIDECDMHQSYCAGGQC 254
+ C H + GG C
Sbjct: 1080 EGPTCSHRAPSCGFHHCH-HGGLC 1102
Score = 62.5 bits (145), Expect = 3e-09
Identities = 78/270 (28%), Positives = 97/270 (35%), Gaps = 40/270 (14%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS---YTCLCEP 67
C ++ F C C PG+ G C ++D C P G C TAGS + C C
Sbjct: 1023 CHSLANAFYCQCLPGHT----GQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPK 1077
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNS-EGSF--QCVCEAGY------RPTATRGAC 118
GF + A C GG C+ S + F +C C +GY P A +G C
Sbjct: 1078 GFEGPTCSHRAP--SCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG-C 1134
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDG-RTCLGLKLGWGVSCQACP 174
C C PG FRC C PG G + C G + G G C
Sbjct: 1135 GPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRCQKPGAKGCEG-RSGDGACDAGCS 1192
Query: 175 AQGSELYAVLCPEG-PSKDNGGADINECTAV--PGACPHGSCENLE---PGYRCICDPGY 228
G C G P G + C + G C H C++ E GY C P
Sbjct: 1193 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQC-HPQCDSEECLFDGYDCETPPAC 1251
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTA 258
P D C D H +C G C NTA
Sbjct: 1252 TPAYDQYCHD----HFHNGHCEKG-C-NTA 1275
Score = 33.1 bits (72), Expect = 2.1
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPG 441
DG C +++D C ++ C GTC G + C CPPG
Sbjct: 961 DGQNCSKELDAC--QSQPCHNHGTCTPKPGGFHCACPPG 997
Score = 32.7 bits (71), Expect = 2.7
Identities = 14/38 (36%), Positives = 17/38 (44%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G TC + S GG+C + G Y C CPP T
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 128 bits (309), Expect = 4e-29
Identities = 135/476 (28%), Positives = 186/476 (39%), Gaps = 75/476 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRG-RCRNTAGS 60
NGG C +G+ + C+C E+ + DVDEC P CR G C+N+AGS
Sbjct: 287 NGGTCQDGL-----DTYTCLCP---ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C+C G+ T+ ++D+C A + G C++ GSF C+C G T C
Sbjct: 339 FHCVCVSGWGGTSCE--ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGLLCHL 392
Query: 121 VDECEEQRVCRNGRCHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLG-----WGVSC 170
D C Q + +C P GS C C PG+ T D CL + G G SC
Sbjct: 393 EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 452
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
P GS + LCP G + AD NEC + P P +C +L + C+C PG
Sbjct: 453 LNTP--GS--FNCLCPPGYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGLEG 507
Query: 231 DADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEG 286
LC +++ + + C C + F C+C P GTR E ++ CR G
Sbjct: 508 Q---LC-EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANG 563
Query: 287 ---ETETHYIESDYERGDIPPTFPTRTE--LASPCDNGR-CINTHGGFECECELGYV--- 337
+ + G P T + L+ PC G C++ G F C C G+
Sbjct: 564 GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQL 623
Query: 338 ---------LDATAQRCLDNR-RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
L Q C D + + +C DG A PE C C G S
Sbjct: 624 CEVPLCAPNLCQPKQICKDQKDKANCL--CPDGSPGCAPPE----DNCTCHHGHCQRSSC 677
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ G C +SA GGTC Y C CP G T
Sbjct: 678 VCDV--------GWT---GPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 722
Score = 120 bits (289), Expect = 1e-26
Identities = 115/419 (27%), Positives = 155/419 (36%), Gaps = 71/419 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
G C N G F C+C PGY G+ C D +EC P C G C + ++ CLC P
Sbjct: 450 GSCLNTPGSFNCLCPPGYT----GSRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPP 503
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
G + +ECA+ C + FQC+C G+ T D+DEC
Sbjct: 504 GLEGQLCE--VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE---DIDECRSS 558
Query: 128 RVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
G+C + PG+F C+CLPGF + CL G SC P + L
Sbjct: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA----FFCL 614
Query: 185 CPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCIC---DPGYHPDAD------G 234
CP G + ++ C P C P C++ + C+C PG P D G
Sbjct: 615 CPSGFTGQL--CEVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHG 670
Query: 235 LCR------DID----ECDMHQSYCA------GGQCRNTAGSFTCVCPEGTRH---EPEL 275
C+ D+ EC+ C GG C + C CP G E+
Sbjct: 671 HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
Query: 276 QLCRDIDECEGETETHYIESDYERGDIP----PTFPTRTE--LASPCDNG-RCINTHGGF 328
C C + Y P P T T+ +++PC NG C+N G F
Sbjct: 731 TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTF 789
Query: 329 ECECELGYVLDATAQRCLDNRRGSCWRRVVDGQC--EAAAPELLLRQECCCSVGLAWGS 385
C C +G+ RC R SC D C A + C C G GS
Sbjct: 790 SCLCAMGF----QGPRCEGKLRPSC----ADSPCRNRATCQDSPQGPRCLCPTGYTGGS 840
Score = 119 bits (287), Expect = 2e-26
Identities = 130/465 (27%), Positives = 183/465 (39%), Gaps = 62/465 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRR-GRCRNT--AGSYT 62
C G C + G F C+C PG G LC D C P C +C GS
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPG----RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTL 417
Query: 63 CLCEPGFA-PTAAGYCADVDECA----ADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRG 116
CLC+PG++ PT D+DEC S C+ GG C+N+ GSF C+C GY T +R
Sbjct: 418 CLCQPGYSGPTCH---QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSR- 471
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP-- 174
D +EC Q C + +F C C PG +G+ C ++ C + P
Sbjct: 472 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGL----EGQLC-EVETN---ECASAPCL 523
Query: 175 --AQGSEL---YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A +L + +C G S DI+EC + P A G C++ + C C PG+
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCA-NGGQCQDQPGAFHCKCLPGF- 581
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPEL-----QLCRDIDE 283
+ ++DEC + G C + G+F C+CP G T E+ LC+
Sbjct: 582 -EGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQI 639
Query: 284 CEGETE-THYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG--GFECECELGYVLDA 340
C+ + + + + D G PP T C C+ G G ECE ELG + A
Sbjct: 640 CKDQKDKANCLCPDGSPGCAPPE-DNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISA 698
Query: 341 TAQRCLDNRRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
C G+C+ + C P C S G
Sbjct: 699 P---CAHG--GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C+ + +SA GGTCVN G++ C C G
Sbjct: 754 TCP--PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
Score = 117 bits (281), Expect = 1e-25
Identities = 126/440 (28%), Positives = 174/440 (39%), Gaps = 51/440 (11%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCR-NTAGSYTCLCEPGFAPTAAGY 76
F C C PG+ E + D C P C +RGRC +G C C PG+
Sbjct: 101 FLCTCLPGFTG--ERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT---GEQ 153
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNG-R 134
C D C+A+ GG C+ + QC C G+ A DV+EC ++ C G
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS 210
Query: 135 CHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
CHNT GSF+C C G C G +CQ P + S + LCP P
Sbjct: 211 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP--PGF 268
Query: 192 DNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH-QSYC 249
++N V C + G+C++ Y C+C P D D+DEC+ +C
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC-PETWTGWD-CSEDVDECETQGPPHC 326
Query: 250 A-GGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
GG C+N+AGSF CVC GT E L C G T I+ + P
Sbjct: 327 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGST---CIDRVGSFSCLCP- 382
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
P RT L ++ C++ + +C + +T C G C
Sbjct: 383 -PGRTGLLCHLED-MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP--------TCHQD 432
Query: 366 APELLLRQE--CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELC 422
E L+ Q+ C G GS G+ G+ C D +EC LS
Sbjct: 433 LDECLMAQQGPSPCEHG---GSCLNTPGSFNCLCPPGYT---GSRCEADHNEC-LSQPCH 485
Query: 423 AGGTCVNTDGSYRCDCPPGL 442
G TC++ ++ C CPPGL
Sbjct: 486 PGSTCLDLLATFHCLCPPGL 505
Score = 111 bits (267), Expect = 5e-24
Identities = 104/354 (29%), Positives = 140/354 (39%), Gaps = 42/354 (11%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS 60
+ G C NG C GG+ C C P + G C+ D C P G C N G+
Sbjct: 734 HSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTDYCVSAP-CFNGGTCVNRPGT 788
Query: 61 YTCLCEPGF-APTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGAC 118
++CLC GF P G + ADS C+ C +S +C+C GY T G+C
Sbjct: 789 FSCLCAMGFQGPRCEG---KLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TGGSC 841
Query: 119 VD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSN-DGRTCLGLKLGWGVSCQACP 174
+D C ++ RN C T SF C CL G+T L N +C L G+ +
Sbjct: 842 QTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 901
Query: 175 AQG------SELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPG 227
G Y CP G +N C + P C +G +C GY C C PG
Sbjct: 902 HNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPG 959
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDEC 284
Y D +++D C + G C G F C CP G R E ++ C D C
Sbjct: 960 Y--DGQNCSKELDACQSQPCH-NHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD-QPC 1015
Query: 285 E--GETETHYIESDYERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELG 335
G H + + + +P E+ PC + C HGG CE G
Sbjct: 1016 HPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCF--HGG-TCEATAG 1066
Score = 110 bits (265), Expect = 9e-24
Identities = 119/470 (25%), Positives = 177/470 (37%), Gaps = 78/470 (16%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C ++ GF+CIC PG+ G C D+DECR +P G+C++ G++ C C PGF
Sbjct: 528 CHDLLNGFQCICLPGFS----GTRCEEDIDECRSSP-CANGGQCQDQPGAFHCKCLPGFE 582
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR------PTATRGACVDVDEC 124
+VDEC +D G C++ G+F C+C +G+ P C C
Sbjct: 583 GPRCQ--TEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 640
Query: 125 EEQR-----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-GVSCQA------ 172
++Q+ +C +G P C C G + +C+ +GW G C+A
Sbjct: 641 KDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS---SCV-CDVGWTGPECEAELGGCI 696
Query: 173 ---CPAQGS-----ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
C G+ Y CP G + ++ C + P GSC GY C C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP-CLNGGSCNPSPGGYYCTC 755
Query: 225 DPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQL---- 277
P + C+ + + GG C N G+F+C+C +G R E +L+
Sbjct: 756 PPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 812
Query: 278 --CRDIDECEGETETH--YIESDYERGDIPPTFPTRTELASPCD-NGRCINTHGGFECEC 332
CR+ C+ + + Y G + PC N C+ T F C C
Sbjct: 813 SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQ--KPCPRNSHCLQTGPSFHCLC 870
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
G+ T C + C+ AA + C G G
Sbjct: 871 LQGW----TGPLC----------NLPLSSCQKAALSQGIDVSSLCHNG---GLCVDSGPS 913
Query: 393 XXXXXXKGFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G+ C+D V+ C S G TC+ Y C C PG
Sbjct: 914 YFCHCPPGF---QGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQCAPG 959
Score = 110 bits (264), Expect = 1e-23
Identities = 138/473 (29%), Positives = 189/473 (39%), Gaps = 89/473 (18%)
Query: 5 GMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCR----NT 57
G C G C N G F+C+C G EG C C PR C G C+
Sbjct: 203 GPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCP--PRGCSNGGTCQLMPEKD 256
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ + CLC PGF + D C + GG C + ++ C+C T T
Sbjct: 257 STFHLCLCPPGFIGPDCE--VNPDNCVSHQCQNGGTCQDGLDTYTCLCPE----TWTGWD 310
Query: 118 CV-DVDECEEQRV--CRNG-RCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSC 170
C DVDECE Q CRNG C N+ GSF C C+ G+ + + C+ G +C
Sbjct: 311 CSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG----SCENLEPGYRCICDP 226
GS ++ LCP G + + + C + P C HG S L C+C P
Sbjct: 371 --IDRVGS--FSCLCPPGRTGLLCHLE-DMCLSQP--C-HGDAQCSTNPLTGSTLCLCQP 422
Query: 227 GYHPDADGLC-RDIDECDMHQ---SYCA-GGQCRNTAGSFTCVCP---EGTRHEPE---- 274
GY + C +D+DEC M Q S C GG C NT GSF C+CP G+R E +
Sbjct: 423 GY---SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 479
Query: 275 -LQLCRDIDECEGETET-HYIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECE 331
Q C C T H + G + T ++PC ++ C + GF+C
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV-ETNECASAPCLNHADCHDLLNGFQCI 538
Query: 332 CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
C G+ + +D R S GQC+ C C G
Sbjct: 539 CLPGF-SGTRCEEDIDECRSSPCAN--GGQCQDQPGAF----HCKCLPG----------- 580
Query: 392 XXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G C+ +VDEC LS G +C++ G++ C CP G T
Sbjct: 581 ------------FEGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFT 620
Score = 96.7 bits (230), Expect = 1e-19
Identities = 119/461 (25%), Positives = 169/461 (36%), Gaps = 71/461 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTC 63
C NG +C +C C PG+ EG C RDV+EC +P C +G C NT GS+ C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 220
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRC---VNSEGSFQ-CVCEAGYRPTATRGACV 119
LC G A C GG C + +F C+C G+ V
Sbjct: 221 LCPVGQEGPRCELRA--GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---V 275
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ D C + G C + ++ C C G+ S D C + C
Sbjct: 276 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ V C G + ++++C A A P +C + + C+C PG GL
Sbjct: 336 AGSFHCV-CVSGWGGTSCEENLDDCIAATCA-PGSTCIDRVGSFSCLCPPG----RTGLL 389
Query: 237 RDIDECDMHQSYCAGGQCRNT--AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
+++ + Q QC GS C+C G P +D+DEC
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPG-YSGPTCH--QDLDEC---------- 436
Query: 295 SDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLDN-- 348
++G SPC++ G C+NT G F C C GY +A CL
Sbjct: 437 LMAQQG------------PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPC 484
Query: 349 RRGS-CWRRVVDGQCEAAAPEL------LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GS C + C P L + EC + L GF
Sbjct: 485 HPGSTCLDLLATFHC-LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ G C D+DEC S+ GG C + G++ C C PG
Sbjct: 544 S---GTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKCLPG 580
Score = 90.6 bits (215), Expect = 1e-17
Identities = 127/462 (27%), Positives = 171/462 (37%), Gaps = 81/462 (17%)
Query: 42 CRDNPRVCRRG-RCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCV--- 95
C P C G C + + G TC C PGF C D C +C+ GG C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQALL 84
Query: 96 -------NSEG----SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH-NTPGSFR 143
+S SF C C G+ T R D C + GRCH G +
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 142
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--YAVL---CPEGPSKDNGGADI 198
C C+PG+T G C +L S C G L Y + CP G D+
Sbjct: 143 CSCMPGWT----GEQC---QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 195
Query: 199 NECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCR- 255
NEC PG CP G SC N ++C+C G +G ++ C+ GG C+
Sbjct: 196 NECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQL 251
Query: 256 ---NTAGSFTCVCPEG-----TRHEPE---LQLCRDIDECEG--ETETHYIESDYERGDI 302
+ C+CP G P+ C++ C+ +T T + D
Sbjct: 252 MPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 311
Query: 303 PPTF-PTRTELASPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGS 352
T+ C N G C N+ G F C C G+ + D A C +
Sbjct: 312 SEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG--ST 369
Query: 353 CWRRV--VDGQCEAAAPELLLRQECCC----SVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
C RV C LL E C G A S G++ G
Sbjct: 370 CIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS---G 426
Query: 407 ATC-RDVDECALSAE---LCA-GGTCVNTDGSYRCDCPPGLT 443
TC +D+DEC ++ + C GG+C+NT GS+ C CPPG T
Sbjct: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
Score = 88.6 bits (210), Expect = 4e-17
Identities = 90/353 (25%), Positives = 130/353 (36%), Gaps = 59/353 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C G+ C C GY G C ++ C P + G C + G Y C C P
Sbjct: 704 GTCYPQPSGYNCTCPTGYT----GPTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPS 758
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
T D C + GG CVN G+F C+C G++ G C +
Sbjct: 759 H--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--RPSCADS- 813
Query: 129 VCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
CRN C ++P RC C G+T +T + L + Q + LC +
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 872
Query: 188 G--------PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRD 238
G P A +++ V C +G C + P Y C C PG+ LC+D
Sbjct: 873 GWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ---GSLCQD 929
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
H + C C+N A TC+ +P LC+ +G+ + +++
Sbjct: 930 ------HVNPCESRPCQNGA---TCMA------QPSGYLCQCAPGYDGQNCSKELDACQ- 973
Query: 299 RGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLD 347
+ PC N G C GGF C C G+V + CLD
Sbjct: 974 --------------SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD 1012
Score = 73.3 bits (172), Expect = 2e-12
Identities = 70/264 (26%), Positives = 97/264 (36%), Gaps = 35/264 (13%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECR--------DNPRVCRRGR-CRNTA 58
N C F C+C G+ G LC + C+ D +C G C ++
Sbjct: 856 NSHCLQTGPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSG 911
Query: 59 GSYTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
SY C C PGF C D V+ C + G C+ + C C GY +
Sbjct: 912 PSYFCHCPPGFQ---GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDG---QNC 965
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACP 174
++D C+ Q +G C PG F C C PGF D CL AC
Sbjct: 966 SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPC-HPTGTAACH 1024
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENL--EP-GYRCICDPGYHP 230
+ + Y C G + +I+ C + P C H G+CE P G+ C C G+
Sbjct: 1025 SLANAFYC-QCLPGHTGQWCEVEIDPCHSQP--CFHGGTCEATAGSPLGFICHCPKGF-- 1079
Query: 231 DADGLCRDIDECDMHQSYCAGGQC 254
+ C H + GG C
Sbjct: 1080 EGPTCSHRAPSCGFHHCH-HGGLC 1102
Score = 62.5 bits (145), Expect = 3e-09
Identities = 78/270 (28%), Positives = 97/270 (35%), Gaps = 40/270 (14%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS---YTCLCEP 67
C ++ F C C PG+ G C ++D C P G C TAGS + C C
Sbjct: 1023 CHSLANAFYCQCLPGHT----GQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPK 1077
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNS-EGSF--QCVCEAGY------RPTATRGAC 118
GF + A C GG C+ S + F +C C +GY P A +G C
Sbjct: 1078 GFEGPTCSHRAP--SCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG-C 1134
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDG-RTCLGLKLGWGVSCQACP 174
C C PG FRC C PG G + C G + G G C
Sbjct: 1135 GPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRCQKPGAKGCEG-RSGDGACDAGCS 1192
Query: 175 AQGSELYAVLCPEG-PSKDNGGADINECTAV--PGACPHGSCENLE---PGYRCICDPGY 228
G C G P G + C + G C H C++ E GY C P
Sbjct: 1193 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQC-HPQCDSEECLFDGYDCETPPAC 1251
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTA 258
P D C D H +C G C NTA
Sbjct: 1252 TPAYDQYCHD----HFHNGHCEKG-C-NTA 1275
Score = 33.1 bits (72), Expect = 2.1
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPG 441
DG C +++D C ++ C GTC G + C CPPG
Sbjct: 961 DGQNCSKELDAC--QSQPCHNHGTCTPKPGGFHCACPPG 997
Score = 32.7 bits (71), Expect = 2.7
Identities = 14/38 (36%), Positives = 17/38 (44%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G TC + S GG+C + G Y C CPP T
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2005
Score = 128 bits (309), Expect = 4e-29
Identities = 135/476 (28%), Positives = 186/476 (39%), Gaps = 75/476 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRG-RCRNTAGS 60
NGG C +G+ + C+C E+ + DVDEC P CR G C+N+AGS
Sbjct: 289 NGGTCQDGL-----DTYTCLCP---ETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGS 340
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C+C G+ T+ ++D+C A + G C++ GSF C+C G T C
Sbjct: 341 FHCVCVSGWGGTSCE--ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGLLCHL 394
Query: 121 VDECEEQRVCRNGRCHNTP--GSFRCECLPGF---TLSNDGRTCLGLKLG-----WGVSC 170
D C Q + +C P GS C C PG+ T D CL + G G SC
Sbjct: 395 EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 454
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
P GS + LCP G + AD NEC + P P +C +L + C+C PG
Sbjct: 455 LNTP--GS--FNCLCPPGYTGSRCEADHNECLSQP-CHPGSTCLDLLATFHCLCPPGLEG 509
Query: 231 DADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVC-P--EGTRHEPELQLCRDIDECEG 286
LC +++ + + C C + F C+C P GTR E ++ CR G
Sbjct: 510 Q---LC-EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANG 565
Query: 287 ---ETETHYIESDYERGDIPPTFPTRTE--LASPCDNGR-CINTHGGFECECELGYV--- 337
+ + G P T + L+ PC G C++ G F C C G+
Sbjct: 566 GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQL 625
Query: 338 ---------LDATAQRCLDNR-RGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
L Q C D + + +C DG A PE C C G S
Sbjct: 626 CEVPLCAPNLCQPKQICKDQKDKANCL--CPDGSPGCAPPE----DNCTCHHGHCQRSSC 679
Query: 388 XXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ G C +SA GGTC Y C CP G T
Sbjct: 680 VCDV--------GWT---GPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT 724
Score = 120 bits (289), Expect = 1e-26
Identities = 115/419 (27%), Positives = 155/419 (36%), Gaps = 71/419 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
G C N G F C+C PGY G+ C D +EC P C G C + ++ CLC P
Sbjct: 452 GSCLNTPGSFNCLCPPGYT----GSRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPP 505
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
G + +ECA+ C + FQC+C G+ T D+DEC
Sbjct: 506 GLEGQLCE--VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE---DIDECRSS 560
Query: 128 RVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
G+C + PG+F C+CLPGF + CL G SC P + L
Sbjct: 561 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA----FFCL 616
Query: 185 CPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPGYRCIC---DPGYHPDAD------G 234
CP G + ++ C P C P C++ + C+C PG P D G
Sbjct: 617 CPSGFTGQL--CEVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHG 672
Query: 235 LCR------DID----ECDMHQSYCA------GGQCRNTAGSFTCVCPEGTRH---EPEL 275
C+ D+ EC+ C GG C + C CP G E+
Sbjct: 673 HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 732
Query: 276 QLCRDIDECEGETETHYIESDYERGDIP----PTFPTRTE--LASPCDNG-RCINTHGGF 328
C C + Y P P T T+ +++PC NG C+N G F
Sbjct: 733 TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTF 791
Query: 329 ECECELGYVLDATAQRCLDNRRGSCWRRVVDGQC--EAAAPELLLRQECCCSVGLAWGS 385
C C +G+ RC R SC D C A + C C G GS
Sbjct: 792 SCLCAMGF----QGPRCEGKLRPSC----ADSPCRNRATCQDSPQGPRCLCPTGYTGGS 842
Score = 119 bits (287), Expect = 2e-26
Identities = 130/465 (27%), Positives = 183/465 (39%), Gaps = 62/465 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRR-GRCRNT--AGSYT 62
C G C + G F C+C PG G LC D C P C +C GS
Sbjct: 366 CAPGSTCIDRVGSFSCLCPPG----RTGLLCHLEDMCLSQP--CHGDAQCSTNPLTGSTL 419
Query: 63 CLCEPGFA-PTAAGYCADVDECA----ADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRG 116
CLC+PG++ PT D+DEC S C+ GG C+N+ GSF C+C GY T +R
Sbjct: 420 CLCQPGYSGPTCH---QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSR- 473
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACP-- 174
D +EC Q C + +F C C PG +G+ C ++ C + P
Sbjct: 474 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGL----EGQLC-EVETN---ECASAPCL 525
Query: 175 --AQGSEL---YAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH 229
A +L + +C G S DI+EC + P A G C++ + C C PG+
Sbjct: 526 NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCA-NGGQCQDQPGAFHCKCLPGF- 583
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPEL-----QLCRDIDE 283
+ ++DEC + G C + G+F C+CP G T E+ LC+
Sbjct: 584 -EGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQI 641
Query: 284 CEGETE-THYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG--GFECECELGYVLDA 340
C+ + + + + D G PP T C C+ G G ECE ELG + A
Sbjct: 642 CKDQKDKANCLCPDGSPGCAPPE-DNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISA 700
Query: 341 TAQRCLDNRRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXX 396
C G+C+ + C P C S G
Sbjct: 701 P---CAHG--GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 755
Query: 397 XXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C+ + +SA GGTCVN G++ C C G
Sbjct: 756 TCP--PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 798
Score = 117 bits (281), Expect = 1e-25
Identities = 126/440 (28%), Positives = 174/440 (39%), Gaps = 51/440 (11%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCR-NTAGSYTCLCEPGFAPTAAGY 76
F C C PG+ G C+ E P C +RGRC +G C C PG+
Sbjct: 103 FLCTCLPGFT----GERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWT---GEQ 155
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNG-R 134
C D C+A+ GG C+ + QC C G+ A DV+EC ++ C G
Sbjct: 156 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS 212
Query: 135 CHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
CHNT GSF+C C G C G +CQ P + S + LCP P
Sbjct: 213 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP--PGF 270
Query: 192 DNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH-QSYC 249
++N V C + G+C++ Y C+C P D D+DEC+ +C
Sbjct: 271 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC-PETWTGWD-CSEDVDECEAQGPPHC 328
Query: 250 A-GGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
GG C+N+AGSF CVC GT E L C G T I+ + P
Sbjct: 329 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGST---CIDRVGSFSCLCP- 384
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
P RT L ++ C++ + +C + +T C G C
Sbjct: 385 -PGRTGLLCHLED-MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP--------TCHQD 434
Query: 366 APELLLRQE--CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELC 422
E L+ Q+ C G GS G+ G+ C D +EC LS
Sbjct: 435 LDECLMAQQGPSPCEHG---GSCLNTPGSFNCLCPPGYT---GSRCEADHNEC-LSQPCH 487
Query: 423 AGGTCVNTDGSYRCDCPPGL 442
G TC++ ++ C CPPGL
Sbjct: 488 PGSTCLDLLATFHCLCPPGL 507
Score = 111 bits (267), Expect = 5e-24
Identities = 104/354 (29%), Positives = 140/354 (39%), Gaps = 42/354 (11%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS 60
+ G C NG C GG+ C C P + G C+ D C P G C N G+
Sbjct: 736 HSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTDYCVSAP-CFNGGTCVNRPGT 790
Query: 61 YTCLCEPGF-APTAAGYCADVDECAADSMCKG-GRCVNSEGSFQCVCEAGYRPTATRGAC 118
++CLC GF P G + ADS C+ C +S +C+C GY T G+C
Sbjct: 791 FSCLCAMGFQGPRCEG---KLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TGGSC 843
Query: 119 VD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSN-DGRTCLGLKLGWGVSCQACP 174
+D C ++ RN C T SF C CL G+T L N +C L G+ +
Sbjct: 844 QTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 903
Query: 175 AQG------SELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPG 227
G Y CP G +N C + P C +G +C GY C C PG
Sbjct: 904 HNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPG 961
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDEC 284
Y D +++D C + G C G F C CP G R E ++ C D C
Sbjct: 962 Y--DGQNCSKELDACQSQPCH-NHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD-QPC 1017
Query: 285 E--GETETHYIESDYERGDIPPTFPTRTEL-ASPCDNGRCINTHGGFECECELG 335
G H + + + +P E+ PC + C HGG CE G
Sbjct: 1018 HPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCF--HGG-TCEATAG 1068
Score = 110 bits (265), Expect = 9e-24
Identities = 119/470 (25%), Positives = 177/470 (37%), Gaps = 78/470 (16%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C ++ GF+CIC PG+ G C D+DECR +P G+C++ G++ C C PGF
Sbjct: 530 CHDLLNGFQCICLPGFS----GTRCEEDIDECRSSP-CANGGQCQDQPGAFHCKCLPGFE 584
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR------PTATRGACVDVDEC 124
+VDEC +D G C++ G+F C+C +G+ P C C
Sbjct: 585 GPRCQ--TEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 642
Query: 125 EEQR-----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-GVSCQA------ 172
++Q+ +C +G P C C G + +C+ +GW G C+A
Sbjct: 643 KDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS---SCV-CDVGWTGPECEAELGGCI 698
Query: 173 ---CPAQGS-----ELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
C G+ Y CP G + ++ C + P GSC GY C C
Sbjct: 699 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP-CLNGGSCNPSPGGYYCTC 757
Query: 225 DPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQL---- 277
P + C+ + + GG C N G+F+C+C +G R E +L+
Sbjct: 758 PPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 814
Query: 278 --CRDIDECEGETETH--YIESDYERGDIPPTFPTRTELASPCD-NGRCINTHGGFECEC 332
CR+ C+ + + Y G + PC N C+ T F C C
Sbjct: 815 SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQ--KPCPRNSHCLQTGPSFHCLC 872
Query: 333 ELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXX 392
G+ T C + C+ AA + C G G
Sbjct: 873 LQGW----TGPLC----------NLPLSSCQKAALSQGIDVSSLCHNG---GLCVDSGPS 915
Query: 393 XXXXXXKGFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF G+ C+D V+ C S G TC+ Y C C PG
Sbjct: 916 YFCHCPPGF---QGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQCAPG 961
Score = 110 bits (264), Expect = 1e-23
Identities = 138/473 (29%), Positives = 189/473 (39%), Gaps = 89/473 (18%)
Query: 5 GMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCR----NT 57
G C G C N G F+C+C G EG C C PR C G C+
Sbjct: 205 GPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCP--PRGCSNGGTCQLMPEKD 258
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ + CLC PGF + D C + GG C + ++ C+C T T
Sbjct: 259 STFHLCLCPPGFIGPDCE--VNPDNCVSHQCQNGGTCQDGLDTYTCLCPE----TWTGWD 312
Query: 118 CV-DVDECEEQRV--CRNG-RCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSC 170
C DVDECE Q CRNG C N+ GSF C C+ G+ + + C+ G +C
Sbjct: 313 CSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 372
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG----SCENLEPGYRCICDP 226
GS ++ LCP G + + + C + P C HG S L C+C P
Sbjct: 373 --IDRVGS--FSCLCPPGRTGLLCHLE-DMCLSQP--C-HGDAQCSTNPLTGSTLCLCQP 424
Query: 227 GYHPDADGLC-RDIDECDMHQ---SYCA-GGQCRNTAGSFTCVCP---EGTRHEPE---- 274
GY + C +D+DEC M Q S C GG C NT GSF C+CP G+R E +
Sbjct: 425 GY---SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 481
Query: 275 -LQLCRDIDECEGETET-HYIESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFECE 331
Q C C T H + G + T ++PC ++ C + GF+C
Sbjct: 482 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV-ETNECASAPCLNHADCHDLLNGFQCI 540
Query: 332 CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXX 391
C G+ + +D R S GQC+ C C G
Sbjct: 541 CLPGF-SGTRCEEDIDECRSSPCAN--GGQCQDQPGAF----HCKCLPG----------- 582
Query: 392 XXXXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
+G C+ +VDEC LS G +C++ G++ C CP G T
Sbjct: 583 ------------FEGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFT 622
Score = 97.5 bits (232), Expect = 9e-20
Identities = 119/461 (25%), Positives = 169/461 (36%), Gaps = 71/461 (15%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTC 63
C NG +C +C C PG+ EG C RDV+EC +P C +G C NT GS+ C
Sbjct: 167 CVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 222
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRC---VNSEGSFQ-CVCEAGYRPTATRGACV 119
LC G A C GG C + +F C+C G+ V
Sbjct: 223 LCPVGQEGPRCELRA--GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE---V 277
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ D C + G C + ++ C C G+ S D C + C
Sbjct: 278 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNS 337
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ V C G + ++++C A A P +C + + C+C PG GL
Sbjct: 338 AGSFHCV-CVSGWGGTSCEENLDDCIAATCA-PGSTCIDRVGSFSCLCPPG----RTGLL 391
Query: 237 RDIDECDMHQSYCAGGQCRNT--AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
+++ + Q QC GS C+C G P +D+DEC
Sbjct: 392 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPG-YSGPTCH--QDLDEC---------- 438
Query: 295 SDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLDN-- 348
++G SPC++ G C+NT G F C C GY +A CL
Sbjct: 439 LMAQQG------------PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPC 486
Query: 349 RRGS-CWRRVVDGQCEAAAPEL------LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
GS C + C P L + EC + L GF
Sbjct: 487 HPGSTCLDLLATFHC-LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 545
Query: 402 AKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+ G C D+DEC S+ GG C + G++ C C PG
Sbjct: 546 S---GTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKCLPG 582
Score = 90.6 bits (215), Expect = 1e-17
Identities = 127/462 (27%), Positives = 170/462 (36%), Gaps = 81/462 (17%)
Query: 42 CRDNPRVCRRG-RCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCV--- 95
C P C G C + + G TC C PGF C D C +C+ GG C
Sbjct: 30 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQALL 86
Query: 96 -------NSEG----SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH-NTPGSFR 143
+S SF C C G+ T R D C + GRCH G +
Sbjct: 87 PAPLGLPSSPSPLTPSFLCTCLPGF--TGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQ 144
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--YAVL---CPEGPSKDNGGADI 198
C C+PG+T G C +L S C G L Y + CP G D+
Sbjct: 145 CSCMPGWT----GEQC---QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 197
Query: 199 NECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCR- 255
NEC PG CP G SC N ++C+C G +G ++ C+ GG C+
Sbjct: 198 NECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQL 253
Query: 256 ---NTAGSFTCVCPEG-----TRHEPE---LQLCRDIDECEG--ETETHYIESDYERGDI 302
+ C+CP G P+ C++ C+ +T T + D
Sbjct: 254 MPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 313
Query: 303 PPTFPTRTELASP-CDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGS 352
P C N G C N+ G F C C G+ + D A C +
Sbjct: 314 SEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG--ST 371
Query: 353 CWRRV--VDGQCEAAAPELLLRQECCC----SVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
C RV C LL E C G A S G++ G
Sbjct: 372 CIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS---G 428
Query: 407 ATC-RDVDECALSAE---LCA-GGTCVNTDGSYRCDCPPGLT 443
TC +D+DEC ++ + C GG+C+NT GS+ C CPPG T
Sbjct: 429 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 470
Score = 88.6 bits (210), Expect = 4e-17
Identities = 90/353 (25%), Positives = 130/353 (36%), Gaps = 59/353 (16%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG 68
G C G+ C C GY G C ++ C P + G C + G Y C C P
Sbjct: 706 GTCYPQPSGYNCTCPTGYT----GPTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPS 760
Query: 69 FAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
T D C + GG CVN G+F C+C G++ G C +
Sbjct: 761 H--TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--RPSCADS- 815
Query: 129 VCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPE 187
CRN C ++P RC C G+T +T + L + Q + LC +
Sbjct: 816 PCRNRATCQDSPQGPRCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 874
Query: 188 G--------PSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRD 238
G P A +++ V C +G C + P Y C C PG+ LC+D
Sbjct: 875 GWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ---GSLCQD 931
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYE 298
H + C C+N A TC+ +P LC+ +G+ + +++
Sbjct: 932 ------HVNPCESRPCQNGA---TCMA------QPSGYLCQCAPGYDGQNCSKELDACQ- 975
Query: 299 RGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYV---LDATAQRCLD 347
+ PC N G C GGF C C G+V + CLD
Sbjct: 976 --------------SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD 1014
Score = 73.3 bits (172), Expect = 2e-12
Identities = 70/264 (26%), Positives = 97/264 (36%), Gaps = 35/264 (13%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECR--------DNPRVCRRGR-CRNTA 58
N C F C+C G+ G LC + C+ D +C G C ++
Sbjct: 858 NSHCLQTGPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSG 913
Query: 59 GSYTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
SY C C PGF C D V+ C + G C+ + C C GY +
Sbjct: 914 PSYFCHCPPGFQ---GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDG---QNC 967
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSCQACP 174
++D C+ Q +G C PG F C C PGF D CL AC
Sbjct: 968 SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPC-HPTGTAACH 1026
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENL--EP-GYRCICDPGYHP 230
+ + Y C G + +I+ C + P C H G+CE P G+ C C G+
Sbjct: 1027 SLANAFYC-QCLPGHTGQWCEVEIDPCHSQP--CFHGGTCEATAGSPLGFICHCPKGF-- 1081
Query: 231 DADGLCRDIDECDMHQSYCAGGQC 254
+ C H + GG C
Sbjct: 1082 EGPTCSHRAPSCGFHHCH-HGGLC 1104
Score = 62.5 bits (145), Expect = 3e-09
Identities = 78/270 (28%), Positives = 97/270 (35%), Gaps = 40/270 (14%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGS---YTCLCEP 67
C ++ F C C PG+ G C ++D C P G C TAGS + C C
Sbjct: 1025 CHSLANAFYCQCLPGHT----GQWCEVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPK 1079
Query: 68 GFAPTAAGYCADVDECAADSMCKGGRCVNS-EGSF--QCVCEAGY------RPTATRGAC 118
GF + A C GG C+ S + F +C C +GY P A +G C
Sbjct: 1080 GFEGPTCSHRAP--SCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG-C 1136
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDG-RTCLGLKLGWGVSCQACP 174
C C PG FRC C PG G + C G + G G C
Sbjct: 1137 GPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRCQKPGAKGCEG-RSGDGACDAGCS 1194
Query: 175 AQGSELYAVLCPEG-PSKDNGGADINECTAV--PGACPHGSCENLE---PGYRCICDPGY 228
G C G P G + C + G C H C++ E GY C P
Sbjct: 1195 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQC-HPQCDSEECLFDGYDCETPPAC 1253
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTA 258
P D C D H +C G C NTA
Sbjct: 1254 TPAYDQYCHD----HFHNGHCEKG-C-NTA 1277
Score = 33.1 bits (72), Expect = 2.1
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 405 DGATC-RDVDECALSAELCAG-GTCVNTDGSYRCDCPPG 441
DG C +++D C ++ C GTC G + C CPPG
Sbjct: 963 DGQNCSKELDAC--QSQPCHNHGTCTPKPGGFHCACPPG 999
Score = 32.7 bits (71), Expect = 2.7
Identities = 14/38 (36%), Positives = 17/38 (44%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G TC + S GG+C + G Y C CPP T
Sbjct: 725 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 762
>AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 128 bits (309), Expect = 4e-29
Identities = 136/469 (28%), Positives = 185/469 (39%), Gaps = 72/469 (15%)
Query: 4 GGMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
G C N CKN+ GG+ C C PG++ G C +V++CR C+ G C++
Sbjct: 429 GKPCLNAFSCKNLIGGYYCDCIPGWK----GINCHINVNDCRGQ---CQHGGTCKDLVNG 481
Query: 61 YTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
Y C+C GF +C + D+CA+ GG C + F C C G+ V
Sbjct: 482 YQCVCPRGFG---GRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---V 535
Query: 120 DVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
DVD CE CRNG RC+N G + C C F G+ C V + CP
Sbjct: 536 DVDLCEPSP-CRNGARCYNLEGDYYCACPDDF----GGKNC-------SVPREPCPGGAC 583
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPG--YRCICDPGYHPDADGL 235
+ +G D G TA G C PHG C + +PG + CICD G+
Sbjct: 584 RVI-----DGCGSDAGPG--MPGTAASGVCGPHGRCVS-QPGGNFSCICDSGF---TGTY 632
Query: 236 CRD-IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI--DECEGETETHY 292
C + ID+C + Q GG C + +F C CP G E D D C +
Sbjct: 633 CHENIDDC-LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYD 691
Query: 293 IESDY----ERGDIPPTFPTRTEL--ASPCDN-GRCINTHGGFECECELGYVLDATA--- 342
+ +D+ + G T +R A C N G C ++ F C C G+ A
Sbjct: 692 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 343 -QRCLDN---RRGSCWRRVVDGQC---EAAAPELLLRQECCCSVGLAW--GSXXXXXXXX 393
CL N G+C C + C+ + G
Sbjct: 752 NSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 811
Query: 394 XXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR ++DEC S+ G TCV+ YRC CPPG
Sbjct: 812 RCECAPGFA---GPDCRINIDECQ-SSPCAYGATCVDEINGYRCSCPPG 856
Score = 126 bits (303), Expect = 2e-28
Identities = 128/461 (27%), Positives = 190/461 (41%), Gaps = 62/461 (13%)
Query: 7 CTNG-ICKNIDGG-FECICKPGYESGSEGALCRDVDE-CRDNPRVCRRGRCRNTAGSYTC 63
CTNG C N + + C C GY G C + C NP G C + C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYS----GRNCEKAEHACTSNP-CANGGSCHEVPSGFEC 371
Query: 64 LCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C G++ PT A D+DECA++ GG CV+ F+C+C + + +D +
Sbjct: 372 HCPSGWSGPTCA---LDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQ---LDAN 425
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGSE 179
ECE + C N G + C+C+PG+ N + C G + G +C+ G
Sbjct: 426 ECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRG-QCQHGGTCKDL-VNG-- 481
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
Y +CP G + + ++C + P C G CE+L G+ C C G+ + LC
Sbjct: 482 -YQCVCPRGFGGRHCELERDKCASSP--CHSGGLCEDLADGFHCHCPQGF---SGPLCEV 535
Query: 238 DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
D+D C+ S C G +C N G + C CP+ + + R + C G I D
Sbjct: 536 DVDLCE--PSPCRNGARCYNLEGDYYCACPDDFGGK-NCSVPR--EPCPGGA-CRVI--D 587
Query: 297 YERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGY--------VLDATAQRCL 346
D P P T + C +GRC++ GG F C C+ G+ + D Q C
Sbjct: 588 GCGSDAGPGMP-GTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCR 646
Query: 347 DNRRGSCWRRVVDGQCEAAA---PEL--LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
+ G+C V +C + EL +C + G G+
Sbjct: 647 NG--GTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 704
Query: 402 AKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
G TC E A C+ GGTC ++ ++RC CPPG
Sbjct: 705 ---KGKTCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPG 741
Score = 113 bits (271), Expect = 2e-24
Identities = 133/473 (28%), Positives = 179/473 (37%), Gaps = 68/473 (14%)
Query: 6 MCTNGICKNIDGGF----ECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
+C G C + GG EC C G++ G C DEC P C G C +
Sbjct: 244 VCKQG-CNLLHGGCTVPGECRCSYGWQ----GRFC---DECVPYPG-CVHGSC---VEPW 291
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMC-KGGRCVNSE-GSFQCVCEAGYRPTATRGACV 119
C CE + D++ C + C GG C+N+E ++C C GY + C
Sbjct: 292 QCNCETNWGGLLCD--KDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNCE 345
Query: 120 DVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+ C NG CH P F C C G++ G TC L + S C A G+
Sbjct: 346 KAEHACTSNPCANGGSCHEVPSGFECHCPSGWS----GPTC-ALDIDECAS-NPCAAGGT 399
Query: 179 -----ELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDA 232
+ + +CPE D NEC P C + SC+NL GY C C PG+
Sbjct: 400 CVDQVDGFECICPEQWVGATCQLDANECEGKP--CLNAFSCKNLIGGYYCDCIPGWK--- 454
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT--RH-EPELQLCRDIDECEG--- 286
G+ I+ D GG C++ + CVCP G RH E E C G
Sbjct: 455 -GINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDKCASSPCHSGGLC 513
Query: 287 ETETHYIESDYERGDIPPTFPTRTELA--SPCDNG-RCINTHGGFECECELGYVLDATAQ 343
E +G P +L SPC NG RC N G + C C D +
Sbjct: 514 EDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPD----DFGGK 569
Query: 344 RCLDNRR----GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK 399
C R G+C RV+DG C + A + G
Sbjct: 570 NCSVPREPCPGGAC--RVIDG-CGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDS 626
Query: 400 GFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
GF G C + +D+C L GGTC++ ++RC CP G + T P
Sbjct: 627 GFT---GTYCHENIDDC-LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNP 675
Score = 100 bits (240), Expect = 9e-21
Identities = 106/392 (27%), Positives = 163/392 (41%), Gaps = 70/392 (17%)
Query: 5 GMC-TNGICKNIDGG-FECICKPGYESGSEGALCRD-VDECRDNPRVCRRG-RCRNTAGS 60
G+C +G C + GG F CIC +SG G C + +D+C P CR G C + +
Sbjct: 604 GVCGPHGRCVSQPGGNFSCIC----DSGFTGTYCHENIDDCLGQP--CRNGGTCIDEVDA 657
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C C G+ + ++C D GRC + F C C+ G++
Sbjct: 658 FRCFCPSGWEGELCD--TNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR--- 712
Query: 121 VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-----GVSCQACPA 175
+C+ G C+++ +FRC C PG+ G TC K V+ C
Sbjct: 713 EFQCDAYTCSNGGTCYDSGDTFRCACPPGW----KGSTCAVAKNSSCLPNPCVNGGTCVG 768
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY-HPDAD 233
G+ ++ +C +G + N+C +P C +G C + +RC C PG+ PD
Sbjct: 769 SGAS-FSCICRDGWEGRTCTHNTNDCNPLP--CYNGGICVDGVNWFRCECAPGFAGPD-- 823
Query: 234 GLCR-DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
CR +IDEC S CA G C + + C CP G R P C+++
Sbjct: 824 --CRINIDEC--QSSPCAYGATCVDEINGYRCSCPPG-RAGPR---CQEV--------IG 867
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE--------CELGYVLDATA- 342
+ S + RG FP + C++ RC++ G +C C L +A +
Sbjct: 868 FGRSCWSRG---TPFPHGSSWVEDCNSCRCLD--GRRDCSKVWCGWKPCLLAGQPEALSA 922
Query: 343 -----QRCLDNRRGSCWRRVVD--GQCEAAAP 367
QRCL+ G C R + G+C A P
Sbjct: 923 QCPLGQRCLEKAPGQCLRPPCEAWGECGAEEP 954
>AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 128 bits (309), Expect = 4e-29
Identities = 136/469 (28%), Positives = 185/469 (39%), Gaps = 72/469 (15%)
Query: 4 GGMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
G C N CKN+ GG+ C C PG++ G C +V++CR C+ G C++
Sbjct: 429 GKPCLNAFSCKNLIGGYYCDCIPGWK----GINCHINVNDCRGQ---CQHGGTCKDLVNG 481
Query: 61 YTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
Y C+C GF +C + D+CA+ GG C + F C C G+ V
Sbjct: 482 YQCVCPRGFG---GRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---V 535
Query: 120 DVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
DVD CE CRNG RC+N G + C C F G+ C V + CP
Sbjct: 536 DVDLCEPSP-CRNGARCYNLEGDYYCACPDDF----GGKNC-------SVPREPCPGGAC 583
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPG--YRCICDPGYHPDADGL 235
+ +G D G TA G C PHG C + +PG + CICD G+
Sbjct: 584 RVI-----DGCGSDAGPG--MPGTAASGVCGPHGRCVS-QPGGNFSCICDSGF---TGTY 632
Query: 236 CRD-IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI--DECEGETETHY 292
C + ID+C + Q GG C + +F C CP G E D D C +
Sbjct: 633 CHENIDDC-LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYD 691
Query: 293 IESDY----ERGDIPPTFPTRTEL--ASPCDN-GRCINTHGGFECECELGYVLDATA--- 342
+ +D+ + G T +R A C N G C ++ F C C G+ A
Sbjct: 692 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 343 -QRCLDN---RRGSCWRRVVDGQC---EAAAPELLLRQECCCSVGLAW--GSXXXXXXXX 393
CL N G+C C + C+ + G
Sbjct: 752 NSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 811
Query: 394 XXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR ++DEC S+ G TCV+ YRC CPPG
Sbjct: 812 RCECAPGFA---GPDCRINIDECQ-SSPCAYGATCVDEINGYRCSCPPG 856
Score = 126 bits (304), Expect = 2e-28
Identities = 128/461 (27%), Positives = 191/461 (41%), Gaps = 62/461 (13%)
Query: 7 CTNG-ICKNIDGG-FECICKPGYESGSEGALCRDVDE-CRDNPRVCRRGRCRNTAGSYTC 63
CTNG C N + + C C GY G C + C NP G C + C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYS----GRNCEKAEHACTSNP-CANGGSCHEVPSGFEC 371
Query: 64 LCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C G++ PT A D+DECA++ GG CV+ F+C+C + + +DV+
Sbjct: 372 HCPSGWSGPTCA---LDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQ---LDVN 425
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGSE 179
+CE + C N G + C+C+PG+ N + C G + G +C+ G
Sbjct: 426 DCEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRG-QCQHGGTCKDL-VNG-- 481
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
Y +CP G + + ++C + P C G CE+L G+ C C G+ + LC
Sbjct: 482 -YQCVCPRGFGGRHCELERDKCASSP--CHSGGLCEDLADGFHCHCPQGF---SGPLCEV 535
Query: 238 DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
D+D C+ S C G +C N G + C CP+ + + R + C G I D
Sbjct: 536 DVDLCE--PSPCRNGARCYNLEGDYYCACPDDFGGK-NCSVPR--EPCPGGA-CRVI--D 587
Query: 297 YERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGY--------VLDATAQRCL 346
D P P T + C +GRC++ GG F C C+ G+ + D Q C
Sbjct: 588 GCGSDAGPGMP-GTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCR 646
Query: 347 DNRRGSCWRRVVDGQCEAAA---PEL--LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
+ G+C V +C + EL +C + G G+
Sbjct: 647 NG--GTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 704
Query: 402 AKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
G TC E A C+ GGTC ++ ++RC CPPG
Sbjct: 705 ---KGKTCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPG 741
Score = 113 bits (272), Expect = 1e-24
Identities = 132/473 (27%), Positives = 180/473 (38%), Gaps = 68/473 (14%)
Query: 6 MCTNGICKNIDGGF----ECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
+C G C + GG EC C G++ G C DEC P C G C +
Sbjct: 244 VCKQG-CNLLHGGCTVPGECRCSYGWQ----GRFC---DECVPYPG-CVHGSC---VEPW 291
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMC-KGGRCVNSE-GSFQCVCEAGYRPTATRGACV 119
C CE + D++ C + C GG C+N+E ++C C GY + C
Sbjct: 292 QCNCETNWGGLLCD--KDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNCE 345
Query: 120 DVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+ C NG CH P F C C G++ G TC L + S C A G+
Sbjct: 346 KAEHACTSNPCANGGSCHEVPSGFECHCPSGWS----GPTC-ALDIDECAS-NPCAAGGT 399
Query: 179 -----ELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDA 232
+ + +CPE D+N+C P C + SC+NL GY C C PG+
Sbjct: 400 CVDQVDGFECICPEQWVGATCQLDVNDCEGKP--CLNAFSCKNLIGGYYCDCIPGWK--- 454
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT--RH-EPELQLCRDIDECEG--- 286
G+ I+ D GG C++ + CVCP G RH E E C G
Sbjct: 455 -GINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDKCASSPCHSGGLC 513
Query: 287 ETETHYIESDYERGDIPPTFPTRTELA--SPCDNG-RCINTHGGFECECELGYVLDATAQ 343
E +G P +L SPC NG RC N G + C C D +
Sbjct: 514 EDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPD----DFGGK 569
Query: 344 RCLDNRR----GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK 399
C R G+C RV+DG C + A + G
Sbjct: 570 NCSVPREPCPGGAC--RVIDG-CGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDS 626
Query: 400 GFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
GF G C + +D+C L GGTC++ ++RC CP G + T P
Sbjct: 627 GFT---GTYCHENIDDC-LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNP 675
Score = 100 bits (240), Expect = 9e-21
Identities = 106/392 (27%), Positives = 163/392 (41%), Gaps = 70/392 (17%)
Query: 5 GMC-TNGICKNIDGG-FECICKPGYESGSEGALCRD-VDECRDNPRVCRRG-RCRNTAGS 60
G+C +G C + GG F CIC +SG G C + +D+C P CR G C + +
Sbjct: 604 GVCGPHGRCVSQPGGNFSCIC----DSGFTGTYCHENIDDCLGQP--CRNGGTCIDEVDA 657
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C C G+ + ++C D GRC + F C C+ G++
Sbjct: 658 FRCFCPSGWEGELCD--TNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR--- 712
Query: 121 VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-----GVSCQACPA 175
+C+ G C+++ +FRC C PG+ G TC K V+ C
Sbjct: 713 EFQCDAYTCSNGGTCYDSGDTFRCACPPGW----KGSTCAVAKNSSCLPNPCVNGGTCVG 768
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY-HPDAD 233
G+ ++ +C +G + N+C +P C +G C + +RC C PG+ PD
Sbjct: 769 SGAS-FSCICRDGWEGRTCTHNTNDCNPLP--CYNGGICVDGVNWFRCECAPGFAGPD-- 823
Query: 234 GLCR-DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
CR +IDEC S CA G C + + C CP G R P C+++
Sbjct: 824 --CRINIDEC--QSSPCAYGATCVDEINGYRCSCPPG-RAGPR---CQEV--------IG 867
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE--------CELGYVLDATA- 342
+ S + RG FP + C++ RC++ G +C C L +A +
Sbjct: 868 FGRSCWSRG---TPFPHGSSWVEDCNSCRCLD--GRRDCSKVWCGWKPCLLAGQPEALSA 922
Query: 343 -----QRCLDNRRGSCWRRVVD--GQCEAAAP 367
QRCL+ G C R + G+C A P
Sbjct: 923 QCPLGQRCLEKAPGQCLRPPCEAWGECGAEEP 954
>AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 128 bits (309), Expect = 4e-29
Identities = 136/469 (28%), Positives = 185/469 (39%), Gaps = 72/469 (15%)
Query: 4 GGMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
G C N CKN+ GG+ C C PG++ G C +V++CR C+ G C++
Sbjct: 429 GKPCLNAFSCKNLIGGYYCDCIPGWK----GINCHINVNDCRGQ---CQHGGTCKDLVNG 481
Query: 61 YTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
Y C+C GF +C + D+CA+ GG C + F C C G+ V
Sbjct: 482 YQCVCPRGFG---GRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---V 535
Query: 120 DVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
DVD CE CRNG RC+N G + C C F G+ C V + CP
Sbjct: 536 DVDLCEPSP-CRNGARCYNLEGDYYCACPDDF----GGKNC-------SVPREPCPGGAC 583
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGAC-PHGSCENLEPG--YRCICDPGYHPDADGL 235
+ +G D G TA G C PHG C + +PG + CICD G+
Sbjct: 584 RVI-----DGCGSDAGPG--MPGTAASGVCGPHGRCVS-QPGGNFSCICDSGF---TGTY 632
Query: 236 CRD-IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI--DECEGETETHY 292
C + ID+C + Q GG C + +F C CP G E D D C +
Sbjct: 633 CHENIDDC-LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYD 691
Query: 293 IESDY----ERGDIPPTFPTRTEL--ASPCDN-GRCINTHGGFECECELGYVLDATA--- 342
+ +D+ + G T +R A C N G C ++ F C C G+ A
Sbjct: 692 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 343 -QRCLDN---RRGSCWRRVVDGQC---EAAAPELLLRQECCCSVGLAW--GSXXXXXXXX 393
CL N G+C C + C+ + G
Sbjct: 752 NSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 811
Query: 394 XXXXXKGFAKLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GFA G CR ++DEC S+ G TCV+ YRC CPPG
Sbjct: 812 RCECAPGFA---GPDCRINIDECQ-SSPCAYGATCVDEINGYRCSCPPG 856
Score = 126 bits (303), Expect = 2e-28
Identities = 128/461 (27%), Positives = 190/461 (41%), Gaps = 62/461 (13%)
Query: 7 CTNG-ICKNIDGG-FECICKPGYESGSEGALCRDVDE-CRDNPRVCRRGRCRNTAGSYTC 63
CTNG C N + + C C GY G C + C NP G C + C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYS----GRNCEKAEHACTSNP-CANGGSCHEVPSGFEC 371
Query: 64 LCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C G++ PT A D+DECA++ GG CV+ F+C+C + + +D +
Sbjct: 372 HCPSGWSGPTCA---LDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQ---LDAN 425
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSCQACPAQGSE 179
ECE + C N G + C+C+PG+ N + C G + G +C+ G
Sbjct: 426 ECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRG-QCQHGGTCKDL-VNG-- 481
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
Y +CP G + + ++C + P C G CE+L G+ C C G+ + LC
Sbjct: 482 -YQCVCPRGFGGRHCELERDKCASSP--CHSGGLCEDLADGFHCHCPQGF---SGPLCEV 535
Query: 238 DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
D+D C+ S C G +C N G + C CP+ + + R + C G I D
Sbjct: 536 DVDLCE--PSPCRNGARCYNLEGDYYCACPDDFGGK-NCSVPR--EPCPGGA-CRVI--D 587
Query: 297 YERGDIPPTFPTRTELASPC-DNGRCINTHGG-FECECELGY--------VLDATAQRCL 346
D P P T + C +GRC++ GG F C C+ G+ + D Q C
Sbjct: 588 GCGSDAGPGMP-GTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCR 646
Query: 347 DNRRGSCWRRVVDGQCEAAA---PEL--LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGF 401
+ G+C V +C + EL +C + G G+
Sbjct: 647 NG--GTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 704
Query: 402 AKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
G TC E A C+ GGTC ++ ++RC CPPG
Sbjct: 705 ---KGKTCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPG 741
Score = 113 bits (271), Expect = 2e-24
Identities = 133/473 (28%), Positives = 179/473 (37%), Gaps = 68/473 (14%)
Query: 6 MCTNGICKNIDGGF----ECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
+C G C + GG EC C G++ G C DEC P C G C +
Sbjct: 244 VCKQG-CNLLHGGCTVPGECRCSYGWQ----GRFC---DECVPYPG-CVHGSC---VEPW 291
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMC-KGGRCVNSE-GSFQCVCEAGYRPTATRGACV 119
C CE + D++ C + C GG C+N+E ++C C GY + C
Sbjct: 292 QCNCETNWGGLLCD--KDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNCE 345
Query: 120 DVDECEEQRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+ C NG CH P F C C G++ G TC L + S C A G+
Sbjct: 346 KAEHACTSNPCANGGSCHEVPSGFECHCPSGWS----GPTC-ALDIDECAS-NPCAAGGT 399
Query: 179 -----ELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDA 232
+ + +CPE D NEC P C + SC+NL GY C C PG+
Sbjct: 400 CVDQVDGFECICPEQWVGATCQLDANECEGKP--CLNAFSCKNLIGGYYCDCIPGWK--- 454
Query: 233 DGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGT--RH-EPELQLCRDIDECEG--- 286
G+ I+ D GG C++ + CVCP G RH E E C G
Sbjct: 455 -GINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDKCASSPCHSGGLC 513
Query: 287 ETETHYIESDYERGDIPPTFPTRTELA--SPCDNG-RCINTHGGFECECELGYVLDATAQ 343
E +G P +L SPC NG RC N G + C C D +
Sbjct: 514 EDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPD----DFGGK 569
Query: 344 RCLDNRR----GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXK 399
C R G+C RV+DG C + A + G
Sbjct: 570 NCSVPREPCPGGAC--RVIDG-CGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDS 626
Query: 400 GFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTAP 451
GF G C + +D+C L GGTC++ ++RC CP G + T P
Sbjct: 627 GFT---GTYCHENIDDC-LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNP 675
Score = 100 bits (240), Expect = 9e-21
Identities = 106/392 (27%), Positives = 163/392 (41%), Gaps = 70/392 (17%)
Query: 5 GMC-TNGICKNIDGG-FECICKPGYESGSEGALCRD-VDECRDNPRVCRRG-RCRNTAGS 60
G+C +G C + GG F CIC +SG G C + +D+C P CR G C + +
Sbjct: 604 GVCGPHGRCVSQPGGNFSCIC----DSGFTGTYCHENIDDCLGQP--CRNGGTCIDEVDA 657
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C C G+ + ++C D GRC + F C C+ G++
Sbjct: 658 FRCFCPSGWEGELCD--TNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR--- 712
Query: 121 VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-----GVSCQACPA 175
+C+ G C+++ +FRC C PG+ G TC K V+ C
Sbjct: 713 EFQCDAYTCSNGGTCYDSGDTFRCACPPGW----KGSTCAVAKNSSCLPNPCVNGGTCVG 768
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY-HPDAD 233
G+ ++ +C +G + N+C +P C +G C + +RC C PG+ PD
Sbjct: 769 SGAS-FSCICRDGWEGRTCTHNTNDCNPLP--CYNGGICVDGVNWFRCECAPGFAGPD-- 823
Query: 234 GLCR-DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
CR +IDEC S CA G C + + C CP G R P C+++
Sbjct: 824 --CRINIDEC--QSSPCAYGATCVDEINGYRCSCPPG-RAGPR---CQEV--------IG 867
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE--------CELGYVLDATA- 342
+ S + RG FP + C++ RC++ G +C C L +A +
Sbjct: 868 FGRSCWSRG---TPFPHGSSWVEDCNSCRCLD--GRRDCSKVWCGWKPCLLAGQPEALSA 922
Query: 343 -----QRCLDNRRGSCWRRVVD--GQCEAAAP 367
QRCL+ G C R + G+C A P
Sbjct: 923 QCPLGQRCLEKAPGQCLRPPCEAWGECGAEEP 954
>CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein.
Length = 448
Score = 127 bits (307), Expect = 7e-29
Identities = 83/234 (35%), Positives = 112/234 (47%), Gaps = 18/234 (7%)
Query: 64 LCEPGFAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDV 121
+C G+ + C DVDECA DS C + C+N+EG + C C GY G C+D+
Sbjct: 112 ICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY--WLLEGQCLDI 169
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSC-QAC-PAQGS 178
DEC C+ C N PGS+ C C PGFTL+ DGR+C + + C Q C GS
Sbjct: 170 DEC-RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGS 227
Query: 179 ELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGY-HPDADG 234
+ C G + G +D++EC+ C H C N Y C C PGY D +
Sbjct: 228 --FICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNR 284
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE 287
C+DI+EC+ C Q C N G F C+ P EP L++ + C E
Sbjct: 285 SCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRC-EEPYLRISDNRCMCPAE 337
Score = 124 bits (299), Expect = 6e-28
Identities = 89/295 (30%), Positives = 127/295 (43%), Gaps = 26/295 (8%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE--- 66
+C G + C G++ + C D+DECR P CR C N G Y C+
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 67 ----PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
P P + Y A + S +C GY+ + CVDVD
Sbjct: 75 VYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTI----SRPLICRFGYQMDESN-QCVDVD 129
Query: 123 ECE-EQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSE 179
EC + C + C NT G + C C G+ L +G+ CL + + +G Q C A
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTCSCTDGYWLL-EGQ-CLDIDECRYGYCQQLC-ANVPG 186
Query: 180 LYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
Y+ C G + + G D+NEC A C +C N + C CDPGY + DG+
Sbjct: 187 SYSCTCNPGFTLNEDGRSCQDVNEC-ATENPCVQ-TCVNTYGSFICRCDPGYELEEDGVH 244
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
C D+DEC + C +C N G++ C CP G + + C+DI+ECE T
Sbjct: 245 CSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHT 298
Score = 118 bits (283), Expect = 6e-26
Identities = 79/226 (34%), Positives = 101/226 (44%), Gaps = 16/226 (7%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADV 80
IC+ GY+ E C DVDEC + C + C NT G YTC C G+ G C D+
Sbjct: 112 ICRFGYQM-DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW-LLEGQCLDI 169
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC C+ C N GS+ C C G+ +C DV+EC + C C NT G
Sbjct: 170 DECRY-GYCQ-QLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ-TCVNTYG 226
Query: 141 SFRCECLPGFTLSNDGRTCLGL-KLGWG-VSCQACPAQGSELYAVLCPEG--PSKDNGGA 196
SF C C PG+ L DG C + + + CQ Y CP G DN
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSC 286
Query: 197 -DINECTAVPGACP-HGSCENLEPGYRCI----CDPGYHPDADGLC 236
DINEC C +C NL+ G++CI C+ Y +D C
Sbjct: 287 QDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRC 332
Score = 109 bits (263), Expect = 1e-23
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 8/144 (5%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTC 63
G C +C N+ G + C C PG+ +G C+DV+EC +NP V C NT GS+ C
Sbjct: 175 GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV---QTCVNTYGSFIC 230
Query: 64 LCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+PG+ G +C+D+DEC+ CVN G++ C C GY +C D++
Sbjct: 231 RCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDIN 290
Query: 123 ECEEQ-RVCR-NGRCHNTPGSFRC 144
ECE + C C+N G F+C
Sbjct: 291 ECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 58.8 bits (136), Expect = 4e-08
Identities = 76/268 (28%), Positives = 100/268 (37%), Gaps = 50/268 (18%)
Query: 197 DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
DI+EC +P AC C N GY CI P +P G + Y A
Sbjct: 42 DIDECRTIPEACRGDMMCVNQNGGYLCI--PRTNPVYRGPYSNPYSTPYSGPYPAAAPPL 99
Query: 256 NTAG----SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
+ S +C G + + Q C D+DEC T++H PT+
Sbjct: 100 SAPNYPTISRPLICRFGYQMDESNQ-CVDVDECA--TDSHQCN------------PTQI- 143
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDN---RRGSCWRRV--VDGQCEAAA 366
CINT GG+ C C GY L +CLD R G C + V G
Sbjct: 144 ---------CINTEGGYTCSCTDGYWL--LEGQCLDIDECRYGYCQQLCANVPGSYSCTC 192
Query: 367 -PELLLRQE---C-----CCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECA 416
P L ++ C C + + G+ + DG C D+DEC+
Sbjct: 193 NPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECS 252
Query: 417 LSAELCAGGTCVNTDGSYRCDCPPGLTL 444
S LC CVN G+Y C CPPG L
Sbjct: 253 FSEFLCQH-ECVNQPGTYFCSCPPGYIL 279
Score = 40.7 bits (91), Expect = 0.010
Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G+ L+G C D+DEC C C N GSY C C PG TL+ G
Sbjct: 158 GYWLLEGQ-CLDIDECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDG 202
Score = 34.3 bits (75), Expect = 0.90
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 1/29 (3%)
Query: 409 CRDVDECALSAELCAGG-TCVNTDGSYRC 436
C D+DEC E C G CVN +G Y C
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein.
Length = 448
Score = 127 bits (307), Expect = 7e-29
Identities = 83/234 (35%), Positives = 112/234 (47%), Gaps = 18/234 (7%)
Query: 64 LCEPGFAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDV 121
+C G+ + C DVDECA DS C + C+N+EG + C C GY G C+D+
Sbjct: 112 ICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY--WLLEGQCLDI 169
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSC-QAC-PAQGS 178
DEC C+ C N PGS+ C C PGFTL+ DGR+C + + C Q C GS
Sbjct: 170 DEC-RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGS 227
Query: 179 ELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGY-HPDADG 234
+ C G + G +D++EC+ C H C N Y C C PGY D +
Sbjct: 228 --FICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNR 284
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE 287
C+DI+EC+ C Q C N G F C+ P EP L++ + C E
Sbjct: 285 SCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRC-EEPYLRISDNRCMCPAE 337
Score = 124 bits (299), Expect = 6e-28
Identities = 89/295 (30%), Positives = 127/295 (43%), Gaps = 26/295 (8%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE--- 66
+C G + C G++ + C D+DECR P CR C N G Y C+
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 67 ----PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
P P + Y A + S +C GY+ + CVDVD
Sbjct: 75 VYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTI----SRPLICRFGYQMDESN-QCVDVD 129
Query: 123 ECE-EQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSE 179
EC + C + C NT G + C C G+ L +G+ CL + + +G Q C A
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTCSCTDGYWLL-EGQ-CLDIDECRYGYCQQLC-ANVPG 186
Query: 180 LYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
Y+ C G + + G D+NEC A C +C N + C CDPGY + DG+
Sbjct: 187 SYSCTCNPGFTLNEDGRSCQDVNEC-ATENPCVQ-TCVNTYGSFICRCDPGYELEEDGVH 244
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
C D+DEC + C +C N G++ C CP G + + C+DI+ECE T
Sbjct: 245 CSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHT 298
Score = 118 bits (283), Expect = 6e-26
Identities = 79/226 (34%), Positives = 101/226 (44%), Gaps = 16/226 (7%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADV 80
IC+ GY+ E C DVDEC + C + C NT G YTC C G+ G C D+
Sbjct: 112 ICRFGYQM-DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW-LLEGQCLDI 169
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC C+ C N GS+ C C G+ +C DV+EC + C C NT G
Sbjct: 170 DECRY-GYCQ-QLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ-TCVNTYG 226
Query: 141 SFRCECLPGFTLSNDGRTCLGL-KLGWG-VSCQACPAQGSELYAVLCPEG--PSKDNGGA 196
SF C C PG+ L DG C + + + CQ Y CP G DN
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSC 286
Query: 197 -DINECTAVPGACP-HGSCENLEPGYRCI----CDPGYHPDADGLC 236
DINEC C +C NL+ G++CI C+ Y +D C
Sbjct: 287 QDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRC 332
Score = 109 bits (263), Expect = 1e-23
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 8/144 (5%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTC 63
G C +C N+ G + C C PG+ +G C+DV+EC +NP V C NT GS+ C
Sbjct: 175 GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV---QTCVNTYGSFIC 230
Query: 64 LCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+PG+ G +C+D+DEC+ CVN G++ C C GY +C D++
Sbjct: 231 RCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDIN 290
Query: 123 ECEEQ-RVCR-NGRCHNTPGSFRC 144
ECE + C C+N G F+C
Sbjct: 291 ECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 58.8 bits (136), Expect = 4e-08
Identities = 76/268 (28%), Positives = 100/268 (37%), Gaps = 50/268 (18%)
Query: 197 DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
DI+EC +P AC C N GY CI P +P G + Y A
Sbjct: 42 DIDECRTIPEACRGDMMCVNQNGGYLCI--PRTNPVYRGPYSNPYSTPYSGPYPAAAPPL 99
Query: 256 NTAG----SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
+ S +C G + + Q C D+DEC T++H PT+
Sbjct: 100 SAPNYPTISRPLICRFGYQMDESNQ-CVDVDECA--TDSHQCN------------PTQI- 143
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDN---RRGSCWRRV--VDGQCEAAA 366
CINT GG+ C C GY L +CLD R G C + V G
Sbjct: 144 ---------CINTEGGYTCSCTDGYWL--LEGQCLDIDECRYGYCQQLCANVPGSYSCTC 192
Query: 367 -PELLLRQE---C-----CCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECA 416
P L ++ C C + + G+ + DG C D+DEC+
Sbjct: 193 NPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECS 252
Query: 417 LSAELCAGGTCVNTDGSYRCDCPPGLTL 444
S LC CVN G+Y C CPPG L
Sbjct: 253 FSEFLCQH-ECVNQPGTYFCSCPPGYIL 279
Score = 40.7 bits (91), Expect = 0.010
Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G+ L+G C D+DEC C C N GSY C C PG TL+ G
Sbjct: 158 GYWLLEGQ-CLDIDECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDG 202
Score = 34.3 bits (75), Expect = 0.90
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 1/29 (3%)
Query: 409 CRDVDECALSAELCAGG-TCVNTDGSYRC 436
C D+DEC E C G CVN +G Y C
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2
precursor protein.
Length = 1285
Score = 127 bits (307), Expect = 7e-29
Identities = 94/302 (31%), Positives = 129/302 (42%), Gaps = 51/302 (16%)
Query: 18 GFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAG 75
GF C C PG++ G C D+DEC P C G CRN A Y C C G+A
Sbjct: 91 GFRCYCVPGFQ----GPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYAGVTCE 144
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRC 135
+VDECA+ GG C++ GSF+CVC GY T + +D+DEC+ Q G C
Sbjct: 145 M--EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQ---LDLDECQSQPCAHGGTC 199
Query: 136 HNTPGSFRCECL----PGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
H+ FRC+C G + C SC +G + LC G S
Sbjct: 200 HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASC----LEGLGSFRCLCWPGYSG 255
Query: 192 DNGGADINECTAVPGACPHGS-C-ENLEP--------------------GYRCICDPGYH 229
+ D +EC + P C HG C + +P G+ C C PG+
Sbjct: 256 ELCEVDEDECASSP--CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFE 313
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE 289
G+ ++DEC + GG C++ F C CP+G P + D+DEC +
Sbjct: 314 GADCGV--EVDEC-ASRPCLNGGHCQDLPNGFQCHCPDGYA-GPTCE--EDVDECLSDPC 367
Query: 290 TH 291
H
Sbjct: 368 LH 369
Score = 98.3 bits (234), Expect = 5e-20
Identities = 78/269 (28%), Positives = 113/269 (42%), Gaps = 43/269 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSY 61
+GG C +G+ G F C+C PGY G C+ D+DEC+ P G C + +
Sbjct: 157 HGGSCLDGV-----GSFRCVCAPGY----GGTRCQLDLDECQSQP-CAHGGTCHDLVNGF 206
Query: 62 TCLCE-PGFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C G+ T +C +V ECA+ C+ GSF+C+C GY V
Sbjct: 207 RCDCAGTGYEGT---HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCE---V 260
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D DEC GRC +D G++ + + A G
Sbjct: 261 DEDECASSPCQHGGRC---------------LQRSDPALYGGVQAAFPGAFSFRHAAG-- 303
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RD 238
+ CP G + G +++EC + P G C++L G++C C GY A C D
Sbjct: 304 -FLCHCPPGFEGADCGVEVDECASRP-CLNGGHCQDLPNGFQCHCPDGY---AGPTCEED 358
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
+DEC + GG C +T + C CPE
Sbjct: 359 VDEC-LSDPCLHGGTCSDTVAGYICRCPE 386
Score = 76.2 bits (179), Expect = 2e-13
Identities = 66/208 (31%), Positives = 77/208 (37%), Gaps = 41/208 (19%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RC------------ 54
N C G F C+C PGY G LC D DEC +P C+ G RC
Sbjct: 235 NASCLEGLGSFRCLCWPGYS----GELCEVDEDECASSP--CQHGGRCLQRSDPALYGGV 288
Query: 55 ----------RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCV 104
R+ AG + C C PGF G +VDECA+ GG C + FQC
Sbjct: 289 QAAFPGAFSFRHAAG-FLCHCPPGFEGADCG--VEVDECASRPCLNGGHCQDLPNGFQCH 345
Query: 105 CEAGYR-PTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCL 160
C GY PT DVDEC G C +T + C C G S C
Sbjct: 346 CPDGYAGPTCEE----DVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQ 401
Query: 161 GLKLGWGVSCQACPAQGSELYAVLCPEG 188
G +C G Y CP G
Sbjct: 402 GHTCPLAATCIPIFESGVHSYVCHCPPG 429
Score = 69.7 bits (163), Expect = 2e-11
Identities = 98/339 (28%), Positives = 131/339 (38%), Gaps = 48/339 (14%)
Query: 125 EEQRVCRNGRCHNTPGSFRCECLP--GFTLSN-DGRTCLGLKLGWGVSC--QACPAQGSE 179
E C + C PG+ C+ G+T + R C G C Q G
Sbjct: 37 EPPSACASDPC--APGT-ECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFR 93
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
Y V +GP + DI+EC + P C HG+ C NL Y C C GY A C
Sbjct: 94 CYCVPGFQGPRCE---LDIDECASRP--CHHGATCRNLADRYECHCPLGY---AGVTCEM 145
Query: 238 DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEG---TRHEPELQLCRDIDECEGETETHYI 293
++DEC + C GG C + GSF CVC G TR + +L C+ G T H +
Sbjct: 146 EVDECA--SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGT-CHDL 202
Query: 294 ESDYERGDIPPTFPTRT-------ELAS-PCD-NGRCINTHGGFECECELGYVLDATAQR 344
+ + R D T T E AS PC+ N C+ G F C C GY + +
Sbjct: 203 VNGF-RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGY----SGEL 257
Query: 345 C-LDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
C +D + G+C + L G GF
Sbjct: 258 CEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPG---AFSFRHAAGFLCHCPPGF-- 312
Query: 404 LDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+GA C +VDECA S GG C + ++C CP G
Sbjct: 313 -EGADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDG 349
Score = 63.7 bits (148), Expect = 1e-09
Identities = 43/146 (29%), Positives = 55/146 (37%), Gaps = 12/146 (8%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCR-NTAGSYTCLCE 66
+G C+++ F C C PG+ EG C VD C P C RGRC + G + C C
Sbjct: 1068 DGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCP 1121
Query: 67 PGFAPTAAGYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
PGF EC+ + C G C + C C G A + V CE
Sbjct: 1122 PGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG---LAGQRCQVPTLPCE 1178
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFT 151
G C G C C F+
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFS 1204
Score = 49.6 bits (113), Expect = 2e-05
Identities = 44/162 (27%), Positives = 53/162 (32%), Gaps = 9/162 (5%)
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
PG G C CA G C + +F C C G+ VD C
Sbjct: 1045 PGTPAPILG-CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCE---AHVDPC-H 1099
Query: 127 QRVCRNGRCHNTP-GSFRCECLPGFTLSNDGRTCLGLKLGWGVSC-QACPAQGSELYA-V 183
C GRCH P G F C C PGF + V+C P +G A
Sbjct: 1100 SAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANC 1159
Query: 184 LCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICD 225
C EG + C A P G+C CIC+
Sbjct: 1160 SCLEGLAGQRCQVPTLPCEANP-CLNGGTCRAAGGVSECICN 1200
Score = 47.6 bits (108), Expect = 9e-05
Identities = 43/143 (30%), Positives = 55/143 (38%), Gaps = 20/143 (13%)
Query: 205 PGACPH-GSCENLEPGYRCICDPGYH-PDADGLCRDIDECDMHQSYCAGGQCR-NTAGSF 261
P C H G+C +L + C C PG+ P + +D C H + CA G+C + G F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEA---HVDPC--HSAPCARGRCHTHPDGRF 1116
Query: 262 TCVCPEG----------TRHEPELQL-CRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
C CP G E L + C D CEG + PT
Sbjct: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
Query: 311 ELASPCDNGRCINTHGGF-ECEC 332
A+PC NG GG EC C
Sbjct: 1177 CEANPCLNGGTCRAAGGVSECIC 1199
Score = 37.1 bits (82), Expect = 0.13
Identities = 19/35 (54%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCP 439
G TC DVDEC LS GGTC +T Y C CP
Sbjct: 352 GPTCEEDVDEC-LSDPCLHGGTCSDTVAGYICRCP 385
Score = 36.7 bits (81), Expect = 0.17
Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 4/68 (5%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C D C+ D GG C+ + F C C A + T C C Q C
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANF----TGPTCAQQLWCPGQPCLPPATCE 860
Query: 137 NTPGSFRC 144
P F C
Sbjct: 861 EVPDGFVC 868
Score = 31.5 bits (68), Expect = 6.3
Identities = 37/155 (23%), Positives = 51/155 (32%), Gaps = 16/155 (10%)
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQ--ACP 174
C C +G C + +F C C PG+ +G C + C C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAPCARGRCH 1109
Query: 175 AQGSELYAVLCPEGPSKDNGGADI--NECTAVPGACPHGS-CENLEPGYRCICDPGYHPD 231
+ CP G + EC ++ C GS CE P C C G
Sbjct: 1110 THPDGRFECRCPPGFGGPRCRLPVPSKEC-SLNVTCLDGSPCEGGSPAANCSCLEGL--- 1165
Query: 232 ADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVC 265
A C+ + + C GG CR G C+C
Sbjct: 1166 AGQRCQ-VPTLPCEANPCLNGGTCRAAGGVSECIC 1199
Score = 31.5 bits (68), Expect = 6.3
Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 4/39 (10%)
Query: 405 DGATCR-DVDECALSAELCAGGTC-VNTDGSYRCDCPPG 441
+G C VD C + CA G C + DG + C CPPG
Sbjct: 1087 EGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCPPG 1123
>AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein.
Length = 448
Score = 127 bits (307), Expect = 7e-29
Identities = 82/233 (35%), Positives = 110/233 (47%), Gaps = 16/233 (6%)
Query: 64 LCEPGFAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDV 121
+C G+ + C DVDECA DS C + C+N+EG + C C GY G C+D+
Sbjct: 112 ICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY--WLLEGQCLDI 169
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSC-QACPAQGSE 179
DEC C+ C N PGS+ C C PGFTL+ DGR+C + + C Q C
Sbjct: 170 DEC-RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGS 227
Query: 180 LYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGY-HPDADGL 235
L C G + G +D++EC+ C H C N Y C C PGY D +
Sbjct: 228 LIC-RCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRS 285
Query: 236 CRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE 287
C+DI+EC+ C Q C N G F C+ P EP L++ + C E
Sbjct: 286 CQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRC-EEPYLRISDNRCMCPAE 337
Score = 122 bits (295), Expect = 2e-27
Identities = 89/295 (30%), Positives = 126/295 (42%), Gaps = 26/295 (8%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE--- 66
+C G + C G++ + C D+DECR P CR C N G Y C+
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 67 ----PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
P P + Y A + S +C GY+ + CVDVD
Sbjct: 75 VYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTI----SRPLICRFGYQMDESN-QCVDVD 129
Query: 123 ECE-EQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSE 179
EC + C + C NT G + C C G+ L +G+ CL + + +G Q C A
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTCSCTDGYWLL-EGQ-CLDIDECRYGYCQQLC-ANVPG 186
Query: 180 LYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
Y+ C G + + G D+NEC A C +C N C CDPGY + DG+
Sbjct: 187 SYSCTCNPGFTLNEDGRSCQDVNEC-ATENPCVQ-TCVNTYGSLICRCDPGYELEEDGVH 244
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
C D+DEC + C +C N G++ C CP G + + C+DI+ECE T
Sbjct: 245 CSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHT 298
Score = 115 bits (277), Expect = 3e-25
Identities = 78/226 (34%), Positives = 100/226 (44%), Gaps = 16/226 (7%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADV 80
IC+ GY+ E C DVDEC + C + C NT G YTC C G+ G C D+
Sbjct: 112 ICRFGYQM-DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW-LLEGQCLDI 169
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC C+ C N GS+ C C G+ +C DV+EC + C C NT G
Sbjct: 170 DECRY-GYCQ-QLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ-TCVNTYG 226
Query: 141 SFRCECLPGFTLSNDGRTCLGL-KLGWG-VSCQACPAQGSELYAVLCPEG--PSKDNGGA 196
S C C PG+ L DG C + + + CQ Y CP G DN
Sbjct: 227 SLICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSC 286
Query: 197 -DINECTAVPGACP-HGSCENLEPGYRCI----CDPGYHPDADGLC 236
DINEC C +C NL+ G++CI C+ Y +D C
Sbjct: 287 QDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRC 332
Score = 108 bits (259), Expect = 5e-23
Identities = 52/144 (36%), Positives = 74/144 (51%), Gaps = 8/144 (5%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTC 63
G C +C N+ G + C C PG+ +G C+DV+EC +NP V C NT GS C
Sbjct: 175 GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV---QTCVNTYGSLIC 230
Query: 64 LCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+PG+ G +C+D+DEC+ CVN G++ C C GY +C D++
Sbjct: 231 RCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDIN 290
Query: 123 ECEEQ-RVCR-NGRCHNTPGSFRC 144
ECE + C C+N G F+C
Sbjct: 291 ECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 58.8 bits (136), Expect = 4e-08
Identities = 76/268 (28%), Positives = 100/268 (37%), Gaps = 50/268 (18%)
Query: 197 DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
DI+EC +P AC C N GY CI P +P G + Y A
Sbjct: 42 DIDECRTIPEACRGDMMCVNQNGGYLCI--PRTNPVYRGPYSNPYSTPYSGPYPAAAPPL 99
Query: 256 NTAG----SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
+ S +C G + + Q C D+DEC T++H PT+
Sbjct: 100 SAPNYPTISRPLICRFGYQMDESNQ-CVDVDECA--TDSHQCN------------PTQI- 143
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDN---RRGSCWRRV--VDGQCEAAA 366
CINT GG+ C C GY L +CLD R G C + V G
Sbjct: 144 ---------CINTEGGYTCSCTDGYWL--LEGQCLDIDECRYGYCQQLCANVPGSYSCTC 192
Query: 367 -PELLLRQE---C-----CCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECA 416
P L ++ C C + + G+ + DG C D+DEC+
Sbjct: 193 NPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSLICRCDPGYELEEDGVHCSDMDECS 252
Query: 417 LSAELCAGGTCVNTDGSYRCDCPPGLTL 444
S LC CVN G+Y C CPPG L
Sbjct: 253 FSEFLCQH-ECVNQPGTYFCSCPPGYIL 279
Score = 40.7 bits (91), Expect = 0.010
Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G+ L+G C D+DEC C C N GSY C C PG TL+ G
Sbjct: 158 GYWLLEGQ-CLDIDECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDG 202
Score = 34.3 bits (75), Expect = 0.90
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 1/29 (3%)
Query: 409 CRDVDECALSAELCAGG-TCVNTDGSYRC 436
C D+DEC E C G CVN +G Y C
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 127 bits (307), Expect = 7e-29
Identities = 94/302 (31%), Positives = 129/302 (42%), Gaps = 51/302 (16%)
Query: 18 GFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAG 75
GF C C PG++ G C D+DEC P C G CRN A Y C C G+A
Sbjct: 91 GFRCYCVPGFQ----GPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYAGVTCE 144
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRC 135
+VDECA+ GG C++ GSF+CVC GY T + +D+DEC+ Q G C
Sbjct: 145 M--EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQ---LDLDECQSQPCAHGGTC 199
Query: 136 HNTPGSFRCECL----PGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
H+ FRC+C G + C SC +G + LC G S
Sbjct: 200 HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASC----LEGLGSFRCLCWPGYSG 255
Query: 192 DNGGADINECTAVPGACPHGS-C-ENLEP--------------------GYRCICDPGYH 229
+ D +EC + P C HG C + +P G+ C C PG+
Sbjct: 256 ELCEVDEDECASSP--CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFE 313
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE 289
G+ ++DEC + GG C++ F C CP+G P + D+DEC +
Sbjct: 314 GADCGV--EVDEC-ASRPCLNGGHCQDLPNGFQCHCPDGYA-GPTCE--EDVDECLSDPC 367
Query: 290 TH 291
H
Sbjct: 368 LH 369
Score = 98.3 bits (234), Expect = 5e-20
Identities = 78/269 (28%), Positives = 113/269 (42%), Gaps = 43/269 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSY 61
+GG C +G+ G F C+C PGY G C+ D+DEC+ P G C + +
Sbjct: 157 HGGSCLDGV-----GSFRCVCAPGY----GGTRCQLDLDECQSQP-CAHGGTCHDLVNGF 206
Query: 62 TCLCE-PGFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C G+ T +C +V ECA+ C+ GSF+C+C GY V
Sbjct: 207 RCDCAGTGYEGT---HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCE---V 260
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D DEC GRC +D G++ + + A G
Sbjct: 261 DEDECASSPCQHGGRC---------------LQRSDPALYGGVQAAFPGAFSFRHAAG-- 303
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RD 238
+ CP G + G +++EC + P G C++L G++C C GY A C D
Sbjct: 304 -FLCHCPPGFEGADCGVEVDECASRP-CLNGGHCQDLPNGFQCHCPDGY---AGPTCEED 358
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
+DEC + GG C +T + C CPE
Sbjct: 359 VDEC-LSDPCLHGGTCSDTVAGYICRCPE 386
Score = 76.2 bits (179), Expect = 2e-13
Identities = 66/208 (31%), Positives = 77/208 (37%), Gaps = 41/208 (19%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RC------------ 54
N C G F C+C PGY G LC D DEC +P C+ G RC
Sbjct: 235 NASCLEGLGSFRCLCWPGYS----GELCEVDEDECASSP--CQHGGRCLQRSDPALYGGV 288
Query: 55 ----------RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCV 104
R+ AG + C C PGF G +VDECA+ GG C + FQC
Sbjct: 289 QAAFPGAFSFRHAAG-FLCHCPPGFEGADCG--VEVDECASRPCLNGGHCQDLPNGFQCH 345
Query: 105 CEAGYR-PTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCL 160
C GY PT DVDEC G C +T + C C G S C
Sbjct: 346 CPDGYAGPTCEE----DVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQ 401
Query: 161 GLKLGWGVSCQACPAQGSELYAVLCPEG 188
G +C G Y CP G
Sbjct: 402 GHTCPLAATCIPIFESGVHSYVCHCPPG 429
Score = 69.7 bits (163), Expect = 2e-11
Identities = 98/339 (28%), Positives = 131/339 (38%), Gaps = 48/339 (14%)
Query: 125 EEQRVCRNGRCHNTPGSFRCECLP--GFTLSN-DGRTCLGLKLGWGVSC--QACPAQGSE 179
E C + C PG+ C+ G+T + R C G C Q G
Sbjct: 37 EPPSACASDPC--APGT-ECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFR 93
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
Y V +GP + DI+EC + P C HG+ C NL Y C C GY A C
Sbjct: 94 CYCVPGFQGPRCE---LDIDECASRP--CHHGATCRNLADRYECHCPLGY---AGVTCEM 145
Query: 238 DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEG---TRHEPELQLCRDIDECEGETETHYI 293
++DEC + C GG C + GSF CVC G TR + +L C+ G T H +
Sbjct: 146 EVDECA--SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGT-CHDL 202
Query: 294 ESDYERGDIPPTFPTRT-------ELAS-PCD-NGRCINTHGGFECECELGYVLDATAQR 344
+ + R D T T E AS PC+ N C+ G F C C GY + +
Sbjct: 203 VNGF-RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGY----SGEL 257
Query: 345 C-LDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
C +D + G+C + L G GF
Sbjct: 258 CEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPG---AFSFRHAAGFLCHCPPGF-- 312
Query: 404 LDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+GA C +VDECA S GG C + ++C CP G
Sbjct: 313 -EGADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDG 349
Score = 63.7 bits (148), Expect = 1e-09
Identities = 43/146 (29%), Positives = 55/146 (37%), Gaps = 12/146 (8%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCR-NTAGSYTCLCE 66
+G C+++ F C C PG+ EG C VD C P C RGRC + G + C C
Sbjct: 1068 DGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCP 1121
Query: 67 PGFAPTAAGYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
PGF EC+ + C G C + C C G A + V CE
Sbjct: 1122 PGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG---LAGQRCQVPTLPCE 1178
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFT 151
G C G C C F+
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFS 1204
Score = 49.6 bits (113), Expect = 2e-05
Identities = 44/162 (27%), Positives = 53/162 (32%), Gaps = 9/162 (5%)
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
PG G C CA G C + +F C C G+ VD C
Sbjct: 1045 PGTPAPILG-CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCE---AHVDPC-H 1099
Query: 127 QRVCRNGRCHNTP-GSFRCECLPGFTLSNDGRTCLGLKLGWGVSC-QACPAQGSELYA-V 183
C GRCH P G F C C PGF + V+C P +G A
Sbjct: 1100 SAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANC 1159
Query: 184 LCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICD 225
C EG + C A P G+C CIC+
Sbjct: 1160 SCLEGLAGQRCQVPTLPCEANP-CLNGGTCRAAGGVSECICN 1200
Score = 47.6 bits (108), Expect = 9e-05
Identities = 43/143 (30%), Positives = 55/143 (38%), Gaps = 20/143 (13%)
Query: 205 PGACPH-GSCENLEPGYRCICDPGYH-PDADGLCRDIDECDMHQSYCAGGQCR-NTAGSF 261
P C H G+C +L + C C PG+ P + +D C H + CA G+C + G F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEA---HVDPC--HSAPCARGRCHTHPDGRF 1116
Query: 262 TCVCPEG----------TRHEPELQL-CRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
C CP G E L + C D CEG + PT
Sbjct: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
Query: 311 ELASPCDNGRCINTHGGF-ECEC 332
A+PC NG GG EC C
Sbjct: 1177 CEANPCLNGGTCRAAGGVSECIC 1199
Score = 37.1 bits (82), Expect = 0.13
Identities = 19/35 (54%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCP 439
G TC DVDEC LS GGTC +T Y C CP
Sbjct: 352 GPTCEEDVDEC-LSDPCLHGGTCSDTVAGYICRCP 385
Score = 36.7 bits (81), Expect = 0.17
Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 4/68 (5%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C D C+ D GG C+ + F C C A + T C C Q C
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANF----TGPTCAQQLWCPGQPCLPPATCE 860
Query: 137 NTPGSFRC 144
P F C
Sbjct: 861 EVPDGFVC 868
Score = 31.5 bits (68), Expect = 6.3
Identities = 37/155 (23%), Positives = 51/155 (32%), Gaps = 16/155 (10%)
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQ--ACP 174
C C +G C + +F C C PG+ +G C + C C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAPCARGRCH 1109
Query: 175 AQGSELYAVLCPEGPSKDNGGADI--NECTAVPGACPHGS-CENLEPGYRCICDPGYHPD 231
+ CP G + EC ++ C GS CE P C C G
Sbjct: 1110 THPDGRFECRCPPGFGGPRCRLPVPSKEC-SLNVTCLDGSPCEGGSPAANCSCLEGL--- 1165
Query: 232 ADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVC 265
A C+ + + C GG CR G C+C
Sbjct: 1166 AGQRCQ-VPTLPCEANPCLNGGTCRAAGGVSECIC 1199
Score = 31.5 bits (68), Expect = 6.3
Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 4/39 (10%)
Query: 405 DGATCR-DVDECALSAELCAGGTC-VNTDGSYRCDCPPG 441
+G C VD C + CA G C + DG + C CPPG
Sbjct: 1087 EGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCPPG 1123
>AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 127 bits (307), Expect = 7e-29
Identities = 94/302 (31%), Positives = 129/302 (42%), Gaps = 51/302 (16%)
Query: 18 GFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAG 75
GF C C PG++ G C D+DEC P C G CRN A Y C C G+A
Sbjct: 91 GFRCYCVPGFQ----GPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYAGVTCE 144
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRC 135
+VDECA+ GG C++ GSF+CVC GY T + +D+DEC+ Q G C
Sbjct: 145 M--EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQ---LDLDECQSQPCAHGGTC 199
Query: 136 HNTPGSFRCECL----PGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
H+ FRC+C G + C SC +G + LC G S
Sbjct: 200 HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASC----LEGLGSFRCLCWPGYSG 255
Query: 192 DNGGADINECTAVPGACPHGS-C-ENLEP--------------------GYRCICDPGYH 229
+ D +EC + P C HG C + +P G+ C C PG+
Sbjct: 256 ELCEVDEDECASSP--CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFE 313
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE 289
G+ ++DEC + GG C++ F C CP+G P + D+DEC +
Sbjct: 314 GADCGV--EVDEC-ASRPCLNGGHCQDLPNGFQCHCPDGYA-GPTCE--EDVDECLSDPC 367
Query: 290 TH 291
H
Sbjct: 368 LH 369
Score = 98.3 bits (234), Expect = 5e-20
Identities = 78/269 (28%), Positives = 113/269 (42%), Gaps = 43/269 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSY 61
+GG C +G+ G F C+C PGY G C+ D+DEC+ P G C + +
Sbjct: 157 HGGSCLDGV-----GSFRCVCAPGY----GGTRCQLDLDECQSQP-CAHGGTCHDLVNGF 206
Query: 62 TCLCE-PGFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C G+ T +C +V ECA+ C+ GSF+C+C GY V
Sbjct: 207 RCDCAGTGYEGT---HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCE---V 260
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D DEC GRC +D G++ + + A G
Sbjct: 261 DEDECASSPCQHGGRC---------------LQRSDPALYGGVQAAFPGAFSFRHAAG-- 303
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RD 238
+ CP G + G +++EC + P G C++L G++C C GY A C D
Sbjct: 304 -FLCHCPPGFEGADCGVEVDECASRP-CLNGGHCQDLPNGFQCHCPDGY---AGPTCEED 358
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
+DEC + GG C +T + C CPE
Sbjct: 359 VDEC-LSDPCLHGGTCSDTVAGYICRCPE 386
Score = 76.2 bits (179), Expect = 2e-13
Identities = 66/208 (31%), Positives = 77/208 (37%), Gaps = 41/208 (19%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RC------------ 54
N C G F C+C PGY G LC D DEC +P C+ G RC
Sbjct: 235 NASCLEGLGSFRCLCWPGYS----GELCEVDEDECASSP--CQHGGRCLQRSDPALYGGV 288
Query: 55 ----------RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCV 104
R+ AG + C C PGF G +VDECA+ GG C + FQC
Sbjct: 289 QAAFPGAFSFRHAAG-FLCHCPPGFEGADCG--VEVDECASRPCLNGGHCQDLPNGFQCH 345
Query: 105 CEAGYR-PTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCL 160
C GY PT DVDEC G C +T + C C G S C
Sbjct: 346 CPDGYAGPTCEE----DVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQ 401
Query: 161 GLKLGWGVSCQACPAQGSELYAVLCPEG 188
G +C G Y CP G
Sbjct: 402 GHTCPLAATCIPIFESGVHSYVCHCPPG 429
Score = 69.7 bits (163), Expect = 2e-11
Identities = 98/339 (28%), Positives = 131/339 (38%), Gaps = 48/339 (14%)
Query: 125 EEQRVCRNGRCHNTPGSFRCECLP--GFTLSN-DGRTCLGLKLGWGVSC--QACPAQGSE 179
E C + C PG+ C+ G+T + R C G C Q G
Sbjct: 37 EPPSACASDPC--APGT-ECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFR 93
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
Y V +GP + DI+EC + P C HG+ C NL Y C C GY A C
Sbjct: 94 CYCVPGFQGPRCE---LDIDECASRP--CHHGATCRNLADRYECHCPLGY---AGVTCEM 145
Query: 238 DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEG---TRHEPELQLCRDIDECEGETETHYI 293
++DEC + C GG C + GSF CVC G TR + +L C+ G T H +
Sbjct: 146 EVDECA--SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGT-CHDL 202
Query: 294 ESDYERGDIPPTFPTRT-------ELAS-PCD-NGRCINTHGGFECECELGYVLDATAQR 344
+ + R D T T E AS PC+ N C+ G F C C GY + +
Sbjct: 203 VNGF-RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGY----SGEL 257
Query: 345 C-LDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
C +D + G+C + L G GF
Sbjct: 258 CEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPG---AFSFRHAAGFLCHCPPGF-- 312
Query: 404 LDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+GA C +VDECA S GG C + ++C CP G
Sbjct: 313 -EGADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDG 349
Score = 48.4 bits (110), Expect = 5e-05
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 8/63 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCR-NTAGSYTCLCE 66
+G C+++ F C C PG+ EG C VD C P C RGRC + G + C C
Sbjct: 1068 DGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCP 1121
Query: 67 PGF 69
PGF
Sbjct: 1122 PGF 1124
Score = 46.4 bits (105), Expect = 2e-04
Identities = 28/85 (32%), Positives = 31/85 (36%), Gaps = 6/85 (7%)
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
PG G C CA G C + +F C C G+ VD C
Sbjct: 1045 PGTPAPILG-CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEA---HVDPCHS 1100
Query: 127 QRVCRNGRCHNTP-GSFRCECLPGF 150
C GRCH P G F C C PGF
Sbjct: 1101 AP-CARGRCHTHPDGRFECRCPPGF 1124
Score = 44.4 bits (100), Expect = 8e-04
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 8/67 (11%)
Query: 205 PGACPH-GSCENLEPGYRCICDPGYH-PDADGLCRDIDECDMHQSYCAGGQCR-NTAGSF 261
P C H G+C +L + C C PG+ P + +D C H + CA G+C + G F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEA---HVDPC--HSAPCARGRCHTHPDGRF 1116
Query: 262 TCVCPEG 268
C CP G
Sbjct: 1117 ECRCPPG 1123
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRC- 94
CR C +P + G CR+ ++ C C PG+ A VD C + + C GRC
Sbjct: 1054 CRGAPVCAPSPCL-HDGACRDLFDAFACACGPGWEGPRCE--AHVDPCHS-APCARGRCH 1109
Query: 95 VNSEGSFQCVCEAGY 109
+ +G F+C C G+
Sbjct: 1110 THPDGRFECRCPPGF 1124
Score = 37.1 bits (82), Expect = 0.13
Identities = 19/35 (54%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCP 439
G TC DVDEC LS GGTC +T Y C CP
Sbjct: 352 GPTCEEDVDEC-LSDPCLHGGTCSDTVAGYICRCP 385
Score = 36.7 bits (81), Expect = 0.17
Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 4/68 (5%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C D C+ D GG C+ + F C C A + T C C Q C
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANF----TGPTCAQQLWCPGQPCLPPATCE 860
Query: 137 NTPGSFRC 144
P F C
Sbjct: 861 EVPDGFVC 868
Score = 31.5 bits (68), Expect = 6.3
Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 4/39 (10%)
Query: 405 DGATCR-DVDECALSAELCAGGTC-VNTDGSYRCDCPPG 441
+G C VD C + CA G C + DG + C CPPG
Sbjct: 1087 EGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCPPG 1123
>AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 127 bits (307), Expect = 7e-29
Identities = 94/302 (31%), Positives = 129/302 (42%), Gaps = 51/302 (16%)
Query: 18 GFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAG 75
GF C C PG++ G C D+DEC P C G CRN A Y C C G+A
Sbjct: 91 GFRCYCVPGFQ----GPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYAGVTCE 144
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRC 135
+VDECA+ GG C++ GSF+CVC GY T + +D+DEC+ Q G C
Sbjct: 145 M--EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQ---LDLDECQSQPCAHGGTC 199
Query: 136 HNTPGSFRCECL----PGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
H+ FRC+C G + C SC +G + LC G S
Sbjct: 200 HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASC----LEGLGSFRCLCWPGYSG 255
Query: 192 DNGGADINECTAVPGACPHGS-C-ENLEP--------------------GYRCICDPGYH 229
+ D +EC + P C HG C + +P G+ C C PG+
Sbjct: 256 ELCEVDEDECASSP--CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFE 313
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE 289
G+ ++DEC + GG C++ F C CP+G P + D+DEC +
Sbjct: 314 GADCGV--EVDEC-ASRPCLNGGHCQDLPNGFQCHCPDGYA-GPTCE--EDVDECLSDPC 367
Query: 290 TH 291
H
Sbjct: 368 LH 369
Score = 98.3 bits (234), Expect = 5e-20
Identities = 78/269 (28%), Positives = 113/269 (42%), Gaps = 43/269 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSY 61
+GG C +G+ G F C+C PGY G C+ D+DEC+ P G C + +
Sbjct: 157 HGGSCLDGV-----GSFRCVCAPGY----GGTRCQLDLDECQSQP-CAHGGTCHDLVNGF 206
Query: 62 TCLCE-PGFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C G+ T +C +V ECA+ C+ GSF+C+C GY V
Sbjct: 207 RCDCAGTGYEGT---HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCE---V 260
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D DEC GRC +D G++ + + A G
Sbjct: 261 DEDECASSPCQHGGRC---------------LQRSDPALYGGVQAAFPGAFSFRHAAG-- 303
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RD 238
+ CP G + G +++EC + P G C++L G++C C GY A C D
Sbjct: 304 -FLCHCPPGFEGADCGVEVDECASRP-CLNGGHCQDLPNGFQCHCPDGY---AGPTCEED 358
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
+DEC + GG C +T + C CPE
Sbjct: 359 VDEC-LSDPCLHGGTCSDTVAGYICRCPE 386
Score = 76.2 bits (179), Expect = 2e-13
Identities = 66/208 (31%), Positives = 77/208 (37%), Gaps = 41/208 (19%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RC------------ 54
N C G F C+C PGY G LC D DEC +P C+ G RC
Sbjct: 235 NASCLEGLGSFRCLCWPGYS----GELCEVDEDECASSP--CQHGGRCLQRSDPALYGGV 288
Query: 55 ----------RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCV 104
R+ AG + C C PGF G +VDECA+ GG C + FQC
Sbjct: 289 QAAFPGAFSFRHAAG-FLCHCPPGFEGADCG--VEVDECASRPCLNGGHCQDLPNGFQCH 345
Query: 105 CEAGYR-PTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCL 160
C GY PT DVDEC G C +T + C C G S C
Sbjct: 346 CPDGYAGPTCEE----DVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQ 401
Query: 161 GLKLGWGVSCQACPAQGSELYAVLCPEG 188
G +C G Y CP G
Sbjct: 402 GHTCPLAATCIPIFESGVHSYVCHCPPG 429
Score = 69.7 bits (163), Expect = 2e-11
Identities = 98/339 (28%), Positives = 131/339 (38%), Gaps = 48/339 (14%)
Query: 125 EEQRVCRNGRCHNTPGSFRCECLP--GFTLSN-DGRTCLGLKLGWGVSC--QACPAQGSE 179
E C + C PG+ C+ G+T + R C G C Q G
Sbjct: 37 EPPSACASDPC--APGT-ECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFR 93
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
Y V +GP + DI+EC + P C HG+ C NL Y C C GY A C
Sbjct: 94 CYCVPGFQGPRCE---LDIDECASRP--CHHGATCRNLADRYECHCPLGY---AGVTCEM 145
Query: 238 DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEG---TRHEPELQLCRDIDECEGETETHYI 293
++DEC + C GG C + GSF CVC G TR + +L C+ G T H +
Sbjct: 146 EVDECA--SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGT-CHDL 202
Query: 294 ESDYERGDIPPTFPTRT-------ELAS-PCD-NGRCINTHGGFECECELGYVLDATAQR 344
+ + R D T T E AS PC+ N C+ G F C C GY + +
Sbjct: 203 VNGF-RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGY----SGEL 257
Query: 345 C-LDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
C +D + G+C + L G GF
Sbjct: 258 CEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPG---AFSFRHAAGFLCHCPPGF-- 312
Query: 404 LDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+GA C +VDECA S GG C + ++C CP G
Sbjct: 313 -EGADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDG 349
Score = 63.7 bits (148), Expect = 1e-09
Identities = 43/146 (29%), Positives = 55/146 (37%), Gaps = 12/146 (8%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCR-NTAGSYTCLCE 66
+G C+++ F C C PG+ EG C VD C P C RGRC + G + C C
Sbjct: 1068 DGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCP 1121
Query: 67 PGFAPTAAGYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
PGF EC+ + C G C + C C G A + V CE
Sbjct: 1122 PGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG---LAGQRCQVPTLPCE 1178
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFT 151
G C G C C F+
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFS 1204
Score = 49.6 bits (113), Expect = 2e-05
Identities = 44/162 (27%), Positives = 53/162 (32%), Gaps = 9/162 (5%)
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
PG G C CA G C + +F C C G+ VD C
Sbjct: 1045 PGTPAPILG-CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCE---AHVDPC-H 1099
Query: 127 QRVCRNGRCHNTP-GSFRCECLPGFTLSNDGRTCLGLKLGWGVSC-QACPAQGSELYA-V 183
C GRCH P G F C C PGF + V+C P +G A
Sbjct: 1100 SAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANC 1159
Query: 184 LCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICD 225
C EG + C A P G+C CIC+
Sbjct: 1160 SCLEGLAGQRCQVPTLPCEANP-CLNGGTCRAAGGVSECICN 1200
Score = 47.6 bits (108), Expect = 9e-05
Identities = 43/143 (30%), Positives = 55/143 (38%), Gaps = 20/143 (13%)
Query: 205 PGACPH-GSCENLEPGYRCICDPGYH-PDADGLCRDIDECDMHQSYCAGGQCR-NTAGSF 261
P C H G+C +L + C C PG+ P + +D C H + CA G+C + G F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEA---HVDPC--HSAPCARGRCHTHPDGRF 1116
Query: 262 TCVCPEG----------TRHEPELQL-CRDIDECEGETETHYIESDYERGDIPPTFPTRT 310
C CP G E L + C D CEG + PT
Sbjct: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
Query: 311 ELASPCDNGRCINTHGGF-ECEC 332
A+PC NG GG EC C
Sbjct: 1177 CEANPCLNGGTCRAAGGVSECIC 1199
Score = 37.1 bits (82), Expect = 0.13
Identities = 19/35 (54%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCP 439
G TC DVDEC LS GGTC +T Y C CP
Sbjct: 352 GPTCEEDVDEC-LSDPCLHGGTCSDTVAGYICRCP 385
Score = 36.7 bits (81), Expect = 0.17
Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 4/68 (5%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C D C+ D GG C+ + F C C A + T C C Q C
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANF----TGPTCAQQLWCPGQPCLPPATCE 860
Query: 137 NTPGSFRC 144
P F C
Sbjct: 861 EVPDGFVC 868
Score = 31.5 bits (68), Expect = 6.3
Identities = 37/155 (23%), Positives = 51/155 (32%), Gaps = 16/155 (10%)
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQ--ACP 174
C C +G C + +F C C PG+ +G C + C C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAPCARGRCH 1109
Query: 175 AQGSELYAVLCPEGPSKDNGGADI--NECTAVPGACPHGS-CENLEPGYRCICDPGYHPD 231
+ CP G + EC ++ C GS CE P C C G
Sbjct: 1110 THPDGRFECRCPPGFGGPRCRLPVPSKEC-SLNVTCLDGSPCEGGSPAANCSCLEGL--- 1165
Query: 232 ADGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVC 265
A C+ + + C GG CR G C+C
Sbjct: 1166 AGQRCQ-VPTLPCEANPCLNGGTCRAAGGVSECIC 1199
Score = 31.5 bits (68), Expect = 6.3
Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 4/39 (10%)
Query: 405 DGATCR-DVDECALSAELCAGGTC-VNTDGSYRCDCPPG 441
+G C VD C + CA G C + DG + C CPPG
Sbjct: 1087 EGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCPPG 1123
>AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 127 bits (307), Expect = 7e-29
Identities = 94/302 (31%), Positives = 129/302 (42%), Gaps = 51/302 (16%)
Query: 18 GFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAG 75
GF C C PG++ G C D+DEC P C G CRN A Y C C G+A
Sbjct: 91 GFRCYCVPGFQ----GPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYAGVTCE 144
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRC 135
+VDECA+ GG C++ GSF+CVC GY T + +D+DEC+ Q G C
Sbjct: 145 M--EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQ---LDLDECQSQPCAHGGTC 199
Query: 136 HNTPGSFRCECL----PGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
H+ FRC+C G + C SC +G + LC G S
Sbjct: 200 HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASC----LEGLGSFRCLCWPGYSG 255
Query: 192 DNGGADINECTAVPGACPHGS-C-ENLEP--------------------GYRCICDPGYH 229
+ D +EC + P C HG C + +P G+ C C PG+
Sbjct: 256 ELCEVDEDECASSP--CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFE 313
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE 289
G+ ++DEC + GG C++ F C CP+G P + D+DEC +
Sbjct: 314 GADCGV--EVDEC-ASRPCLNGGHCQDLPNGFQCHCPDGYA-GPTCE--EDVDECLSDPC 367
Query: 290 TH 291
H
Sbjct: 368 LH 369
Score = 98.3 bits (234), Expect = 5e-20
Identities = 78/269 (28%), Positives = 113/269 (42%), Gaps = 43/269 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSY 61
+GG C +G+ G F C+C PGY G C+ D+DEC+ P G C + +
Sbjct: 157 HGGSCLDGV-----GSFRCVCAPGY----GGTRCQLDLDECQSQP-CAHGGTCHDLVNGF 206
Query: 62 TCLCE-PGFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
C C G+ T +C +V ECA+ C+ GSF+C+C GY V
Sbjct: 207 RCDCAGTGYEGT---HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCE---V 260
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
D DEC GRC +D G++ + + A G
Sbjct: 261 DEDECASSPCQHGGRC---------------LQRSDPALYGGVQAAFPGAFSFRHAAG-- 303
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC-RD 238
+ CP G + G +++EC + P G C++L G++C C GY A C D
Sbjct: 304 -FLCHCPPGFEGADCGVEVDECASRP-CLNGGHCQDLPNGFQCHCPDGY---AGPTCEED 358
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
+DEC + GG C +T + C CPE
Sbjct: 359 VDEC-LSDPCLHGGTCSDTVAGYICRCPE 386
Score = 76.2 bits (179), Expect = 2e-13
Identities = 66/208 (31%), Positives = 77/208 (37%), Gaps = 41/208 (19%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RC------------ 54
N C G F C+C PGY G LC D DEC +P C+ G RC
Sbjct: 235 NASCLEGLGSFRCLCWPGYS----GELCEVDEDECASSP--CQHGGRCLQRSDPALYGGV 288
Query: 55 ----------RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCV 104
R+ AG + C C PGF G +VDECA+ GG C + FQC
Sbjct: 289 QAAFPGAFSFRHAAG-FLCHCPPGFEGADCG--VEVDECASRPCLNGGHCQDLPNGFQCH 345
Query: 105 CEAGYR-PTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCL 160
C GY PT DVDEC G C +T + C C G S C
Sbjct: 346 CPDGYAGPTCEE----DVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQ 401
Query: 161 GLKLGWGVSCQACPAQGSELYAVLCPEG 188
G +C G Y CP G
Sbjct: 402 GHTCPLAATCIPIFESGVHSYVCHCPPG 429
Score = 69.7 bits (163), Expect = 2e-11
Identities = 98/339 (28%), Positives = 131/339 (38%), Gaps = 48/339 (14%)
Query: 125 EEQRVCRNGRCHNTPGSFRCECLP--GFTLSN-DGRTCLGLKLGWGVSC--QACPAQGSE 179
E C + C PG+ C+ G+T + R C G C Q G
Sbjct: 37 EPPSACASDPC--APGT-ECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFR 93
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
Y V +GP + DI+EC + P C HG+ C NL Y C C GY A C
Sbjct: 94 CYCVPGFQGPRCE---LDIDECASRP--CHHGATCRNLADRYECHCPLGY---AGVTCEM 145
Query: 238 DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEG---TRHEPELQLCRDIDECEGETETHYI 293
++DEC + C GG C + GSF CVC G TR + +L C+ G T H +
Sbjct: 146 EVDECA--SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGT-CHDL 202
Query: 294 ESDYERGDIPPTFPTRT-------ELAS-PCD-NGRCINTHGGFECECELGYVLDATAQR 344
+ + R D T T E AS PC+ N C+ G F C C GY + +
Sbjct: 203 VNGF-RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGY----SGEL 257
Query: 345 C-LDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
C +D + G+C + L G GF
Sbjct: 258 CEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPG---AFSFRHAAGFLCHCPPGF-- 312
Query: 404 LDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+GA C +VDECA S GG C + ++C CP G
Sbjct: 313 -EGADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDG 349
Score = 48.4 bits (110), Expect = 5e-05
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 8/63 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCR-NTAGSYTCLCE 66
+G C+++ F C C PG+ EG C VD C P C RGRC + G + C C
Sbjct: 1068 DGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCP 1121
Query: 67 PGF 69
PGF
Sbjct: 1122 PGF 1124
Score = 46.4 bits (105), Expect = 2e-04
Identities = 28/85 (32%), Positives = 31/85 (36%), Gaps = 6/85 (7%)
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
PG G C CA G C + +F C C G+ VD C
Sbjct: 1045 PGTPAPILG-CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEA---HVDPCHS 1100
Query: 127 QRVCRNGRCHNTP-GSFRCECLPGF 150
C GRCH P G F C C PGF
Sbjct: 1101 AP-CARGRCHTHPDGRFECRCPPGF 1124
Score = 44.4 bits (100), Expect = 8e-04
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 8/67 (11%)
Query: 205 PGACPH-GSCENLEPGYRCICDPGYH-PDADGLCRDIDECDMHQSYCAGGQCR-NTAGSF 261
P C H G+C +L + C C PG+ P + +D C H + CA G+C + G F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEA---HVDPC--HSAPCARGRCHTHPDGRF 1116
Query: 262 TCVCPEG 268
C CP G
Sbjct: 1117 ECRCPPG 1123
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRC- 94
CR C +P + G CR+ ++ C C PG+ A VD C + + C GRC
Sbjct: 1054 CRGAPVCAPSPCL-HDGACRDLFDAFACACGPGWEGPRCE--AHVDPCHS-APCARGRCH 1109
Query: 95 VNSEGSFQCVCEAGY 109
+ +G F+C C G+
Sbjct: 1110 THPDGRFECRCPPGF 1124
Score = 37.1 bits (82), Expect = 0.13
Identities = 19/35 (54%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCP 439
G TC DVDEC LS GGTC +T Y C CP
Sbjct: 352 GPTCEEDVDEC-LSDPCLHGGTCSDTVAGYICRCP 385
Score = 36.7 bits (81), Expect = 0.17
Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 4/68 (5%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C D C+ D GG C+ + F C C A + T C C Q C
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANF----TGPTCAQQLWCPGQPCLPPATCE 860
Query: 137 NTPGSFRC 144
P F C
Sbjct: 861 EVPDGFVC 868
Score = 31.5 bits (68), Expect = 6.3
Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 4/39 (10%)
Query: 405 DGATCR-DVDECALSAELCAGGTC-VNTDGSYRCDCPPG 441
+G C VD C + CA G C + DG + C CPPG
Sbjct: 1087 EGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCPPG 1123
>AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein.
Length = 448
Score = 127 bits (307), Expect = 7e-29
Identities = 83/234 (35%), Positives = 112/234 (47%), Gaps = 18/234 (7%)
Query: 64 LCEPGFAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDV 121
+C G+ + C DVDECA DS C + C+N+EG + C C GY G C+D+
Sbjct: 112 ICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY--WLLEGQCLDI 169
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSC-QAC-PAQGS 178
DEC C+ C N PGS+ C C PGFTL+ DGR+C + + C Q C GS
Sbjct: 170 DEC-RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGS 227
Query: 179 ELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGY-HPDADG 234
+ C G + G +D++EC+ C H C N Y C C PGY D +
Sbjct: 228 --FICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNR 284
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE 287
C+DI+EC+ C Q C N G F C+ P EP L++ + C E
Sbjct: 285 SCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRC-EEPYLRISDNRCMCPAE 337
Score = 124 bits (299), Expect = 6e-28
Identities = 89/295 (30%), Positives = 127/295 (43%), Gaps = 26/295 (8%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE--- 66
+C G + C G++ + C D+DECR P CR C N G Y C+
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 67 ----PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
P P + Y A + S +C GY+ + CVDVD
Sbjct: 75 VYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTI----SRPLICRFGYQMDESN-QCVDVD 129
Query: 123 ECE-EQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSE 179
EC + C + C NT G + C C G+ L +G+ CL + + +G Q C A
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTCSCTDGYWLL-EGQ-CLDIDECRYGYCQQLC-ANVPG 186
Query: 180 LYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
Y+ C G + + G D+NEC A C +C N + C CDPGY + DG+
Sbjct: 187 SYSCTCNPGFTLNEDGRSCQDVNEC-ATENPCVQ-TCVNTYGSFICRCDPGYELEEDGVH 244
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
C D+DEC + C +C N G++ C CP G + + C+DI+ECE T
Sbjct: 245 CSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHT 298
Score = 118 bits (283), Expect = 6e-26
Identities = 79/226 (34%), Positives = 101/226 (44%), Gaps = 16/226 (7%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADV 80
IC+ GY+ E C DVDEC + C + C NT G YTC C G+ G C D+
Sbjct: 112 ICRFGYQM-DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW-LLEGQCLDI 169
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC C+ C N GS+ C C G+ +C DV+EC + C C NT G
Sbjct: 170 DECRY-GYCQ-QLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ-TCVNTYG 226
Query: 141 SFRCECLPGFTLSNDGRTCLGL-KLGWG-VSCQACPAQGSELYAVLCPEG--PSKDNGGA 196
SF C C PG+ L DG C + + + CQ Y CP G DN
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSC 286
Query: 197 -DINECTAVPGACP-HGSCENLEPGYRCI----CDPGYHPDADGLC 236
DINEC C +C NL+ G++CI C+ Y +D C
Sbjct: 287 QDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRC 332
Score = 109 bits (263), Expect = 1e-23
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 8/144 (5%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTC 63
G C +C N+ G + C C PG+ +G C+DV+EC +NP V C NT GS+ C
Sbjct: 175 GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV---QTCVNTYGSFIC 230
Query: 64 LCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+PG+ G +C+D+DEC+ CVN G++ C C GY +C D++
Sbjct: 231 RCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDIN 290
Query: 123 ECEEQ-RVCR-NGRCHNTPGSFRC 144
ECE + C C+N G F+C
Sbjct: 291 ECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 58.8 bits (136), Expect = 4e-08
Identities = 76/268 (28%), Positives = 100/268 (37%), Gaps = 50/268 (18%)
Query: 197 DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
DI+EC +P AC C N GY CI P +P G + Y A
Sbjct: 42 DIDECRTIPEACRGDMMCVNQNGGYLCI--PRTNPVYRGPYSNPYSTPYSGPYPAAAPPL 99
Query: 256 NTAG----SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
+ S +C G + + Q C D+DEC T++H PT+
Sbjct: 100 SAPNYPTISRPLICRFGYQMDESNQ-CVDVDECA--TDSHQCN------------PTQI- 143
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDN---RRGSCWRRV--VDGQCEAAA 366
CINT GG+ C C GY L +CLD R G C + V G
Sbjct: 144 ---------CINTEGGYTCSCTDGYWL--LEGQCLDIDECRYGYCQQLCANVPGSYSCTC 192
Query: 367 -PELLLRQE---C-----CCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECA 416
P L ++ C C + + G+ + DG C D+DEC+
Sbjct: 193 NPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECS 252
Query: 417 LSAELCAGGTCVNTDGSYRCDCPPGLTL 444
S LC CVN G+Y C CPPG L
Sbjct: 253 FSEFLCQH-ECVNQPGTYFCSCPPGYIL 279
Score = 40.7 bits (91), Expect = 0.010
Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G+ L+G C D+DEC C C N GSY C C PG TL+ G
Sbjct: 158 GYWLLEGQ-CLDIDECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDG 202
Score = 34.3 bits (75), Expect = 0.90
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 1/29 (3%)
Query: 409 CRDVDECALSAELCAGG-TCVNTDGSYRC 436
C D+DEC E C G CVN +G Y C
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries and
neural crest EGF-like protein protein.
Length = 448
Score = 127 bits (307), Expect = 7e-29
Identities = 83/234 (35%), Positives = 112/234 (47%), Gaps = 18/234 (7%)
Query: 64 LCEPGFAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDV 121
+C G+ + C DVDECA DS C + C+N+EG + C C GY G C+D+
Sbjct: 112 ICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY--WLLEGQCLDI 169
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSC-QAC-PAQGS 178
DEC C+ C N PGS+ C C PGFTL+ DGR+C + + C Q C GS
Sbjct: 170 DEC-RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGS 227
Query: 179 ELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGY-HPDADG 234
+ C G + G +D++EC+ C H C N Y C C PGY D +
Sbjct: 228 --FICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNR 284
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE 287
C+DI+EC+ C Q C N G F C+ P EP L++ + C E
Sbjct: 285 SCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRC-EEPYLRISDNRCMCPAE 337
Score = 124 bits (299), Expect = 6e-28
Identities = 89/295 (30%), Positives = 127/295 (43%), Gaps = 26/295 (8%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE--- 66
+C G + C G++ + C D+DECR P CR C N G Y C+
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 67 ----PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
P P + Y A + S +C GY+ + CVDVD
Sbjct: 75 VYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTI----SRPLICRFGYQMDESN-QCVDVD 129
Query: 123 ECE-EQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSE 179
EC + C + C NT G + C C G+ L +G+ CL + + +G Q C A
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTCSCTDGYWLL-EGQ-CLDIDECRYGYCQQLC-ANVPG 186
Query: 180 LYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
Y+ C G + + G D+NEC A C +C N + C CDPGY + DG+
Sbjct: 187 SYSCTCNPGFTLNEDGRSCQDVNEC-ATENPCVQ-TCVNTYGSFICRCDPGYELEEDGVH 244
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
C D+DEC + C +C N G++ C CP G + + C+DI+ECE T
Sbjct: 245 CSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHT 298
Score = 118 bits (283), Expect = 6e-26
Identities = 79/226 (34%), Positives = 101/226 (44%), Gaps = 16/226 (7%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADV 80
IC+ GY+ E C DVDEC + C + C NT G YTC C G+ G C D+
Sbjct: 112 ICRFGYQM-DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW-LLEGQCLDI 169
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC C+ C N GS+ C C G+ +C DV+EC + C C NT G
Sbjct: 170 DECRY-GYCQ-QLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ-TCVNTYG 226
Query: 141 SFRCECLPGFTLSNDGRTCLGL-KLGWG-VSCQACPAQGSELYAVLCPEG--PSKDNGGA 196
SF C C PG+ L DG C + + + CQ Y CP G DN
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSC 286
Query: 197 -DINECTAVPGACP-HGSCENLEPGYRCI----CDPGYHPDADGLC 236
DINEC C +C NL+ G++CI C+ Y +D C
Sbjct: 287 QDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRC 332
Score = 109 bits (263), Expect = 1e-23
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 8/144 (5%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTC 63
G C +C N+ G + C C PG+ +G C+DV+EC +NP V C NT GS+ C
Sbjct: 175 GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV---QTCVNTYGSFIC 230
Query: 64 LCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+PG+ G +C+D+DEC+ CVN G++ C C GY +C D++
Sbjct: 231 RCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDIN 290
Query: 123 ECEEQ-RVCR-NGRCHNTPGSFRC 144
ECE + C C+N G F+C
Sbjct: 291 ECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 58.8 bits (136), Expect = 4e-08
Identities = 76/268 (28%), Positives = 100/268 (37%), Gaps = 50/268 (18%)
Query: 197 DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
DI+EC +P AC C N GY CI P +P G + Y A
Sbjct: 42 DIDECRTIPEACRGDMMCVNQNGGYLCI--PRTNPVYRGPYSNPYSTPYSGPYPAAAPPL 99
Query: 256 NTAG----SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
+ S +C G + + Q C D+DEC T++H PT+
Sbjct: 100 SAPNYPTISRPLICRFGYQMDESNQ-CVDVDECA--TDSHQCN------------PTQI- 143
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDN---RRGSCWRRV--VDGQCEAAA 366
CINT GG+ C C GY L +CLD R G C + V G
Sbjct: 144 ---------CINTEGGYTCSCTDGYWL--LEGQCLDIDECRYGYCQQLCANVPGSYSCTC 192
Query: 367 -PELLLRQE---C-----CCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECA 416
P L ++ C C + + G+ + DG C D+DEC+
Sbjct: 193 NPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECS 252
Query: 417 LSAELCAGGTCVNTDGSYRCDCPPGLTL 444
S LC CVN G+Y C CPPG L
Sbjct: 253 FSEFLCQH-ECVNQPGTYFCSCPPGYIL 279
Score = 40.7 bits (91), Expect = 0.010
Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G+ L+G C D+DEC C C N GSY C C PG TL+ G
Sbjct: 158 GYWLLEGQ-CLDIDECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDG 202
Score = 34.3 bits (75), Expect = 0.90
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 1/29 (3%)
Query: 409 CRDVDECALSAELCAGG-TCVNTDGSYRC 436
C D+DEC E C G CVN +G Y C
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein.
Length = 815
Score = 127 bits (306), Expect = 9e-29
Identities = 82/247 (33%), Positives = 105/247 (42%), Gaps = 20/247 (8%)
Query: 35 LCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAA--GYCADVDECA-ADSMCK- 90
+C+ D C + CRN C C GF YC D+DECA C+
Sbjct: 393 VCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRE 452
Query: 91 GGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVC-RNGRCHNTPGSFRCECLP 148
CVN+ GSF C+C+ GY +C + DEC Q C N C NT G C C P
Sbjct: 453 NTMCVNTPGSFMCICKTGY-IRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKP 511
Query: 149 GFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGAC 208
G+T +G TC + AC A CP+G + + DI+EC+ C
Sbjct: 512 GYT--GNGTTCKAFCKDGCRNGGACIAAN----VCACPQGFTGPSCETDIDECSDGFVQC 565
Query: 209 -PHGSCENLEPGYRCICDPGYHPD-----ADGLCRDIDECDMHQSYCAGGQ-CRNTAGSF 261
+C NL Y C C GYH + + C DIDEC + CA C N G +
Sbjct: 566 DSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGY 625
Query: 262 TCVCPEG 268
C CP G
Sbjct: 626 DCRCPHG 632
Score = 104 bits (250), Expect = 6e-22
Identities = 71/238 (29%), Positives = 99/238 (41%), Gaps = 21/238 (8%)
Query: 9 NGICKNIDGGFECICKPGYESGSE-GALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
N IC+N++ C C+ G+ + E A C D+DEC + CR C NT GS+ C+C+
Sbjct: 409 NSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICK 468
Query: 67 PGFAPTAAGYCADVDECAADS-MC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ C + DEC + C + C N+ G CVC+ GY T D C
Sbjct: 469 TGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGC 528
Query: 125 EEQRVCRNGRCHNTPGSF---RC-----ECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
C P F C EC GF + C+ L GW C+
Sbjct: 529 RNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLP-GW-YHCEC--RD 584
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDAD 233
G + P G S + DI+EC +C + + C NL+ GY C C G + D
Sbjct: 585 GYHDNGMFSPSGESCE----DIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD 638
Score = 78.2 bits (184), Expect = 6e-14
Identities = 54/164 (32%), Positives = 70/164 (42%), Gaps = 20/164 (12%)
Query: 1 MTNGGMCT-NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAG 59
+TN C N +C N GG C+CKPGY G C+ C+D CR G A
Sbjct: 486 ITNQHNCDENALCFNTVGGHNCVCKPGYT--GNGTTCKAF--CKDG---CRNGGACIAAN 538
Query: 60 SYTCLCEPGFAPTAAGYCADVDECAADSM-CKG-GRCVNSEGSFQCVCEAGYRP----TA 113
C C GF T D+DEC+ + C C+N G + C C GY +
Sbjct: 539 --VCACPQGF--TGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSP 594
Query: 114 TRGACVDVDECEEQR-VCRNGR-CHNTPGSFRCECLPGFTLSND 155
+ +C D+DEC R C N C N G + C C G + D
Sbjct: 595 SGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD 638
Score = 77.4 bits (182), Expect = 1e-13
Identities = 100/381 (26%), Positives = 134/381 (35%), Gaps = 66/381 (17%)
Query: 89 CKGGRCVNSEGSFQC---VCEAGYRPTATRGACVDVDECEE-QRVCR-NGRCHNTPGSFR 143
CK C+N G+ QC +C P + A VD C+E + +C+ GR +
Sbjct: 290 CKNCTCLN--GTIQCETLICPNPDCPLKSALAYVDGKCCKECKSICQFQGRTYFEGERNT 347
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYAVLCPEGPSKDNGGADINECT 202
G + + + +KL V CPA E + + K G D C+
Sbjct: 348 VYSSSGVCVLYECKDQT-MKL---VESSGCPALDCPESHQITLSHSCCKVCKGYDF--CS 401
Query: 203 AVPGACPHGSCENLEPGYRCICDPGYHP--DADGLCRDIDECDMHQSYCAGG-QCRNTAG 259
+ C NL C C G+ + + C DIDEC + YC C NT G
Sbjct: 402 ERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPG 461
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG 319
SF C+C G + C + DEC T H + +N
Sbjct: 462 SFMCICKTGYIRIDDYS-CTEHDECI--TNQHNCD----------------------ENA 496
Query: 320 RCINTHGGFECECELGYVLDATAQR--CLDNRR--GSCWRRVVDGQCEAAAPELLLRQEC 375
C NT GG C C+ GY + T + C D R G+C + C A P+ C
Sbjct: 497 LCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGAC---IAANVC--ACPQGFTGPSC 551
Query: 376 C-----CSVGLAWGSXXXXXXXX---------XXXXXKGFAKLDGATCRDVDECALSAEL 421
CS G G G +C D+DEC
Sbjct: 552 ETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHS 611
Query: 422 CAGGT-CVNTDGSYRCDCPPG 441
CA T C N DG Y C CP G
Sbjct: 612 CANDTICFNLDGGYDCRCPHG 632
Score = 66.9 bits (156), Expect = 1e-10
Identities = 82/315 (26%), Positives = 117/315 (37%), Gaps = 37/315 (11%)
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDECEEQR-VCR-N 132
+C++ C +S+C+ N C C G+R A C D+DEC E R CR N
Sbjct: 399 FCSERHNCMENSICR-----NLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCREN 453
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRT-----CLGLKLGWGVSCQACPAQGSELYAVLCPE 187
C NTPGSF C C G+ +D C+ + + G + +C
Sbjct: 454 TMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGG--HNCVCKP 511
Query: 188 GPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH-PDADGLCRDIDECDMHQ 246
G + G + G G+C C C G+ P + DIDEC
Sbjct: 512 GYT---GNGTTCKAFCKDGCRNGGACIAANV---CACPQGFTGPSCE---TDIDECSDGF 562
Query: 247 SYC-AGGQCRNTAGSFTCVCPEGTRHE----PELQLCRDIDECEGETETHYIESDYERGD 301
C + C N G + C C +G P + C DIDEC T H +D +
Sbjct: 563 VQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDEC--GTGRHSCANDTICFN 620
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC-LDNRRGSCWRRVVDG 360
+ + R C G CI+ G + ++ + + C N C R V D
Sbjct: 621 LDGGYDCRCPHGKNC-TGDCIH-DGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCD- 677
Query: 361 QCEAAAPELLLRQEC 375
CE +L EC
Sbjct: 678 -CENPTVDLFCCPEC 691
Score = 40.7 bits (91), Expect = 0.010
Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDST 447
G+ ++D +C + DEC + C C NT G + C C PG T + T
Sbjct: 470 GYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGT 518
>D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2
protein.
Length = 816
Score = 127 bits (306), Expect = 9e-29
Identities = 82/247 (33%), Positives = 105/247 (42%), Gaps = 20/247 (8%)
Query: 35 LCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAA--GYCADVDECA-ADSMCK- 90
+C+ D C + CRN C C GF YC D+DECA C+
Sbjct: 394 VCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRE 453
Query: 91 GGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVC-RNGRCHNTPGSFRCECLP 148
CVN+ GSF C+C+ GY +C + DEC Q C N C NT G C C P
Sbjct: 454 NTMCVNTPGSFMCICKTGY-IRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKP 512
Query: 149 GFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGAC 208
G+T +G TC + AC A CP+G + + DI+EC+ C
Sbjct: 513 GYT--GNGTTCKAFCKDGCRNGGACIAAN----VCACPQGFTGPSCETDIDECSDGFVQC 566
Query: 209 -PHGSCENLEPGYRCICDPGYHPD-----ADGLCRDIDECDMHQSYCAGGQ-CRNTAGSF 261
+C NL Y C C GYH + + C DIDEC + CA C N G +
Sbjct: 567 DSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGY 626
Query: 262 TCVCPEG 268
C CP G
Sbjct: 627 DCRCPHG 633
Score = 104 bits (250), Expect = 6e-22
Identities = 71/238 (29%), Positives = 99/238 (41%), Gaps = 21/238 (8%)
Query: 9 NGICKNIDGGFECICKPGYESGSE-GALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
N IC+N++ C C+ G+ + E A C D+DEC + CR C NT GS+ C+C+
Sbjct: 410 NSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICK 469
Query: 67 PGFAPTAAGYCADVDECAADS-MC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ C + DEC + C + C N+ G CVC+ GY T D C
Sbjct: 470 TGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGC 529
Query: 125 EEQRVCRNGRCHNTPGSF---RC-----ECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
C P F C EC GF + C+ L GW C+
Sbjct: 530 RNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLP-GW-YHCEC--RD 585
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDAD 233
G + P G S + DI+EC +C + + C NL+ GY C C G + D
Sbjct: 586 GYHDNGMFSPSGESCE----DIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD 639
Score = 78.2 bits (184), Expect = 6e-14
Identities = 54/164 (32%), Positives = 70/164 (42%), Gaps = 20/164 (12%)
Query: 1 MTNGGMCT-NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAG 59
+TN C N +C N GG C+CKPGY G C+ C+D CR G A
Sbjct: 487 ITNQHNCDENALCFNTVGGHNCVCKPGYT--GNGTTCKAF--CKDG---CRNGGACIAAN 539
Query: 60 SYTCLCEPGFAPTAAGYCADVDECAADSM-CKG-GRCVNSEGSFQCVCEAGYRP----TA 113
C C GF T D+DEC+ + C C+N G + C C GY +
Sbjct: 540 --VCACPQGF--TGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSP 595
Query: 114 TRGACVDVDECEEQR-VCRNGR-CHNTPGSFRCECLPGFTLSND 155
+ +C D+DEC R C N C N G + C C G + D
Sbjct: 596 SGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD 639
Score = 77.4 bits (182), Expect = 1e-13
Identities = 100/381 (26%), Positives = 134/381 (35%), Gaps = 66/381 (17%)
Query: 89 CKGGRCVNSEGSFQC---VCEAGYRPTATRGACVDVDECEE-QRVCR-NGRCHNTPGSFR 143
CK C+N G+ QC +C P + A VD C+E + +C+ GR +
Sbjct: 291 CKNCTCLN--GTIQCETLICPNPDCPLKSALAYVDGKCCKECKSICQFQGRTYFEGERNT 348
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYAVLCPEGPSKDNGGADINECT 202
G + + + +KL V CPA E + + K G D C+
Sbjct: 349 VYSSSGVCVLYECKDQT-MKL---VESSGCPALDCPESHQITLSHSCCKVCKGYDF--CS 402
Query: 203 AVPGACPHGSCENLEPGYRCICDPGYHP--DADGLCRDIDECDMHQSYCAGG-QCRNTAG 259
+ C NL C C G+ + + C DIDEC + YC C NT G
Sbjct: 403 ERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPG 462
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG 319
SF C+C G + C + DEC T H + +N
Sbjct: 463 SFMCICKTGYIRIDDYS-CTEHDECI--TNQHNCD----------------------ENA 497
Query: 320 RCINTHGGFECECELGYVLDATAQR--CLDNRR--GSCWRRVVDGQCEAAAPELLLRQEC 375
C NT GG C C+ GY + T + C D R G+C + C A P+ C
Sbjct: 498 LCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGAC---IAANVC--ACPQGFTGPSC 552
Query: 376 C-----CSVGLAWGSXXXXXXXX---------XXXXXKGFAKLDGATCRDVDECALSAEL 421
CS G G G +C D+DEC
Sbjct: 553 ETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHS 612
Query: 422 CAGGT-CVNTDGSYRCDCPPG 441
CA T C N DG Y C CP G
Sbjct: 613 CANDTICFNLDGGYDCRCPHG 633
Score = 66.9 bits (156), Expect = 1e-10
Identities = 82/315 (26%), Positives = 117/315 (37%), Gaps = 37/315 (11%)
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDECEEQR-VCR-N 132
+C++ C +S+C+ N C C G+R A C D+DEC E R CR N
Sbjct: 400 FCSERHNCMENSICR-----NLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCREN 454
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRT-----CLGLKLGWGVSCQACPAQGSELYAVLCPE 187
C NTPGSF C C G+ +D C+ + + G + +C
Sbjct: 455 TMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGG--HNCVCKP 512
Query: 188 GPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH-PDADGLCRDIDECDMHQ 246
G + G + G G+C C C G+ P + DIDEC
Sbjct: 513 GYT---GNGTTCKAFCKDGCRNGGACIAANV---CACPQGFTGPSCE---TDIDECSDGF 563
Query: 247 SYC-AGGQCRNTAGSFTCVCPEGTRHE----PELQLCRDIDECEGETETHYIESDYERGD 301
C + C N G + C C +G P + C DIDEC T H +D +
Sbjct: 564 VQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDEC--GTGRHSCANDTICFN 621
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC-LDNRRGSCWRRVVDG 360
+ + R C G CI+ G + ++ + + C N C R V D
Sbjct: 622 LDGGYDCRCPHGKNC-TGDCIH-DGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCD- 678
Query: 361 QCEAAAPELLLRQEC 375
CE +L EC
Sbjct: 679 -CENPTVDLFCCPEC 692
Score = 40.7 bits (91), Expect = 0.010
Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDST 447
G+ ++D +C + DEC + C C NT G + C C PG T + T
Sbjct: 471 GYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGT 519
>BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein.
Length = 816
Score = 127 bits (306), Expect = 9e-29
Identities = 82/247 (33%), Positives = 105/247 (42%), Gaps = 20/247 (8%)
Query: 35 LCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAA--GYCADVDECA-ADSMCK- 90
+C+ D C + CRN C C GF YC D+DECA C+
Sbjct: 394 VCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRE 453
Query: 91 GGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVC-RNGRCHNTPGSFRCECLP 148
CVN+ GSF C+C+ GY +C + DEC Q C N C NT G C C P
Sbjct: 454 NTMCVNTPGSFMCICKTGY-IRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKP 512
Query: 149 GFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGAC 208
G+T +G TC + AC A CP+G + + DI+EC+ C
Sbjct: 513 GYT--GNGTTCKAFCKDGCRNGGACIAAN----VCACPQGFTGPSCETDIDECSDGFVQC 566
Query: 209 -PHGSCENLEPGYRCICDPGYHPD-----ADGLCRDIDECDMHQSYCAGGQ-CRNTAGSF 261
+C NL Y C C GYH + + C DIDEC + CA C N G +
Sbjct: 567 DSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGY 626
Query: 262 TCVCPEG 268
C CP G
Sbjct: 627 DCRCPHG 633
Score = 104 bits (250), Expect = 6e-22
Identities = 71/238 (29%), Positives = 99/238 (41%), Gaps = 21/238 (8%)
Query: 9 NGICKNIDGGFECICKPGYESGSE-GALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
N IC+N++ C C+ G+ + E A C D+DEC + CR C NT GS+ C+C+
Sbjct: 410 NSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICK 469
Query: 67 PGFAPTAAGYCADVDECAADS-MC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
G+ C + DEC + C + C N+ G CVC+ GY T D C
Sbjct: 470 TGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGC 529
Query: 125 EEQRVCRNGRCHNTPGSF---RC-----ECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
C P F C EC GF + C+ L GW C+
Sbjct: 530 RNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLP-GW-YHCEC--RD 585
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDAD 233
G + P G S + DI+EC +C + + C NL+ GY C C G + D
Sbjct: 586 GYHDNGMFSPSGESCE----DIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD 639
Score = 78.2 bits (184), Expect = 6e-14
Identities = 54/164 (32%), Positives = 70/164 (42%), Gaps = 20/164 (12%)
Query: 1 MTNGGMCT-NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAG 59
+TN C N +C N GG C+CKPGY G C+ C+D CR G A
Sbjct: 487 ITNQHNCDENALCFNTVGGHNCVCKPGYT--GNGTTCKAF--CKDG---CRNGGACIAAN 539
Query: 60 SYTCLCEPGFAPTAAGYCADVDECAADSM-CKG-GRCVNSEGSFQCVCEAGYRP----TA 113
C C GF T D+DEC+ + C C+N G + C C GY +
Sbjct: 540 --VCACPQGF--TGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSP 595
Query: 114 TRGACVDVDECEEQR-VCRNGR-CHNTPGSFRCECLPGFTLSND 155
+ +C D+DEC R C N C N G + C C G + D
Sbjct: 596 SGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGD 639
Score = 77.4 bits (182), Expect = 1e-13
Identities = 100/381 (26%), Positives = 134/381 (35%), Gaps = 66/381 (17%)
Query: 89 CKGGRCVNSEGSFQC---VCEAGYRPTATRGACVDVDECEE-QRVCR-NGRCHNTPGSFR 143
CK C+N G+ QC +C P + A VD C+E + +C+ GR +
Sbjct: 291 CKNCTCLN--GTIQCETLICPNPDCPLKSALAYVDGKCCKECKSICQFQGRTYFEGERNT 348
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS-ELYAVLCPEGPSKDNGGADINECT 202
G + + + +KL V CPA E + + K G D C+
Sbjct: 349 VYSSSGVCVLYECKDQT-MKL---VESSGCPALDCPESHQITLSHSCCKVCKGYDF--CS 402
Query: 203 AVPGACPHGSCENLEPGYRCICDPGYHP--DADGLCRDIDECDMHQSYCAGG-QCRNTAG 259
+ C NL C C G+ + + C DIDEC + YC C NT G
Sbjct: 403 ERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPG 462
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG 319
SF C+C G + C + DEC T H + +N
Sbjct: 463 SFMCICKTGYIRIDDYS-CTEHDECI--TNQHNCD----------------------ENA 497
Query: 320 RCINTHGGFECECELGYVLDATAQR--CLDNRR--GSCWRRVVDGQCEAAAPELLLRQEC 375
C NT GG C C+ GY + T + C D R G+C + C A P+ C
Sbjct: 498 LCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGAC---IAANVC--ACPQGFTGPSC 552
Query: 376 C-----CSVGLAWGSXXXXXXXX---------XXXXXKGFAKLDGATCRDVDECALSAEL 421
CS G G G +C D+DEC
Sbjct: 553 ETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHS 612
Query: 422 CAGGT-CVNTDGSYRCDCPPG 441
CA T C N DG Y C CP G
Sbjct: 613 CANDTICFNLDGGYDCRCPHG 633
Score = 66.9 bits (156), Expect = 1e-10
Identities = 82/315 (26%), Positives = 117/315 (37%), Gaps = 37/315 (11%)
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDECEEQR-VCR-N 132
+C++ C +S+C+ N C C G+R A C D+DEC E R CR N
Sbjct: 400 FCSERHNCMENSICR-----NLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCREN 454
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRT-----CLGLKLGWGVSCQACPAQGSELYAVLCPE 187
C NTPGSF C C G+ +D C+ + + G + +C
Sbjct: 455 TMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGG--HNCVCKP 512
Query: 188 GPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYH-PDADGLCRDIDECDMHQ 246
G + G + G G+C C C G+ P + DIDEC
Sbjct: 513 GYT---GNGTTCKAFCKDGCRNGGACIAANV---CACPQGFTGPSCE---TDIDECSDGF 563
Query: 247 SYC-AGGQCRNTAGSFTCVCPEGTRHE----PELQLCRDIDECEGETETHYIESDYERGD 301
C + C N G + C C +G P + C DIDEC T H +D +
Sbjct: 564 VQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDEC--GTGRHSCANDTICFN 621
Query: 302 IPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC-LDNRRGSCWRRVVDG 360
+ + R C G CI+ G + ++ + + C N C R V D
Sbjct: 622 LDGGYDCRCPHGKNC-TGDCIH-DGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCD- 678
Query: 361 QCEAAAPELLLRQEC 375
CE +L EC
Sbjct: 679 -CENPTVDLFCCPEC 692
Score = 40.7 bits (91), Expect = 0.010
Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDST 447
G+ ++D +C + DEC + C C NT G + C C PG T + T
Sbjct: 471 GYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGT 519
>X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane
protein protein.
Length = 835
Score = 126 bits (305), Expect = 1e-28
Identities = 67/160 (41%), Positives = 88/160 (55%), Gaps = 21/160 (13%)
Query: 12 CKNIDGGFECICKPGYE--SGSEGA------LCRDVDECRDNPRVCRR-GRCRNTAGSYT 62
C N +G ++C+C PGYE SG++ C+DVDEC+ NPR+C+ G C NT GSYT
Sbjct: 82 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 141
Query: 63 CLCEPG--FAPTAAGYCADVDEC-AADSMCKGG-RCVNSEGSFQCVCEAGYRPT------ 112
C C PG F P C DV+EC + + C C+N+ GS+QC C G++P
Sbjct: 142 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 201
Query: 113 ATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGF 150
C DVDEC Q C + C NT GS+ C C PG+
Sbjct: 202 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241
Score = 97.1 bits (231), Expect = 1e-19
Identities = 75/233 (32%), Positives = 103/233 (44%), Gaps = 54/233 (23%)
Query: 21 CICKPGYESGSE-----GALCRDVDECRDNPRV-CRR-GRCRNTAGSYTCLCEPGFAPTA 73
C C PG+ S SE C D++EC +V C + C NT GSY C+C PG+ P +
Sbjct: 42 CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 101
Query: 74 A---------GYCADVDECAAD-SMCKG-GRCVNSEGSFQCVCEAGYR--PTATRGACVD 120
C DVDEC + +CK G CVN+ GS+ C C G++ P + C D
Sbjct: 102 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK-VCTD 160
Query: 121 VDECEE-QRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
V+EC Q C + C N GS++C C PG+ P GS
Sbjct: 161 VNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ----------------------PIPGS 198
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHP 230
P GP+ + D++EC++ C + C N Y C C PG+ P
Sbjct: 199 -------PNGPN-NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 243
Score = 78.6 bits (185), Expect = 4e-14
Identities = 42/121 (34%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 3 NGGMCTN-GICKNIDGGFECICKPGYESGSEGA-LCRDVDECRDNPRVCRRG-RCRNTAG 59
N +C + G C N G + C C PG++ E +C DV+EC C C N G
Sbjct: 123 NPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVG 182
Query: 60 SYTCLCEPGFAPTAAG-------YCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYR 110
SY C C PG+ P C DVDEC++ C C N+ GS+ C C G++
Sbjct: 183 SYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242
Query: 111 P 111
P
Sbjct: 243 P 243
Score = 78.2 bits (184), Expect = 6e-14
Identities = 57/179 (31%), Positives = 78/179 (43%), Gaps = 40/179 (22%)
Query: 197 DINECTAVPGACPHGS---CENLEPGYRCICDPGYHP---------DADGLCRDIDECDM 244
DINEC A P G C N E Y C+C PGY P +++ C+D+DEC
Sbjct: 64 DINEC-ATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQ 122
Query: 245 HQSYCAG-GQCRNTAGSFTCVCPEGTRHEPE-LQLCRDIDECEG-----ETETHYIES-- 295
+ C G C NT GS+TC C G + PE ++C D++EC + TH + +
Sbjct: 123 NPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVG 182
Query: 296 DYERGDIP--------PTFPTRT--ELASPCDNGR--------CINTHGGFECECELGY 336
Y+ P P P T E C +G+ C NT G + C C G+
Sbjct: 183 SYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241
Score = 74.5 bits (175), Expect = 7e-13
Identities = 58/215 (26%), Positives = 84/215 (39%), Gaps = 44/215 (20%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR---CHNTP 139
C +S C F E PT T C D++EC G+ C NT
Sbjct: 30 CPQNSSCVNATACRCNPGFSSFSEIITTPTET---CDDINECATPSKVSCGKFSDCWNTE 86
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN 199
GS+ C C PG+ P G++ + +N D++
Sbjct: 87 GSYDCVCSPGYE----------------------PVSGAKTFK------NESENTCQDVD 118
Query: 200 ECTAVPGACP-HGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYC-AGGQCR 255
EC P C +G+C N Y C C PG+ P+ +C D++EC Q+ C + C
Sbjct: 119 ECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCL 178
Query: 256 NTAGSFTCVCPEGTR------HEPELQLCRDIDEC 284
N GS+ C C G + + P +C D+DEC
Sbjct: 179 NNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDEC 213
Score = 55.6 bits (128), Expect = 3e-07
Identities = 65/258 (25%), Positives = 91/258 (35%), Gaps = 45/258 (17%)
Query: 195 GADINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGL------CRDIDECDMHQS 247
GA+ + CP + SC N C C+PG+ ++ + C DI+EC
Sbjct: 17 GAETQDSRGCARWCPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSK 73
Query: 248 YCAG--GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
G C NT GS+ CVC G +EP +T ES+ D+
Sbjct: 74 VSCGKFSDCWNTEGSYDCVCSPG--YEPV-----------SGAKTFKNESENTCQDVDEC 120
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGY-VLDATAQRCLDNRRGSCWRRVVDGQCEA 364
S G C+NT G + C+C G+ + + C D + +
Sbjct: 121 QQNPRLCKS---YGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 177
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
+ +C C G W + C DVDEC+ C
Sbjct: 178 L--NNVGSYQCRCRPG--WQPIPGSPNGP-----------NNTVCEDVDECSSGQHQCDS 222
Query: 425 GT-CVNTDGSYRCDCPPG 441
T C NT GSY C C PG
Sbjct: 223 STVCFNTVGSYSCRCRPG 240
>U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein.
Length = 835
Score = 126 bits (305), Expect = 1e-28
Identities = 67/160 (41%), Positives = 88/160 (55%), Gaps = 21/160 (13%)
Query: 12 CKNIDGGFECICKPGYE--SGSEGA------LCRDVDECRDNPRVCRR-GRCRNTAGSYT 62
C N +G ++C+C PGYE SG++ C+DVDEC+ NPR+C+ G C NT GSYT
Sbjct: 82 CWNTEGSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 141
Query: 63 CLCEPG--FAPTAAGYCADVDEC-AADSMCKGG-RCVNSEGSFQCVCEAGYRPT------ 112
C C PG F P C DV+EC + + C C+N+ GS+QC C G++P
Sbjct: 142 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 201
Query: 113 ATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGF 150
C DVDEC Q C + C NT GS+ C C PG+
Sbjct: 202 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241
Score = 97.1 bits (231), Expect = 1e-19
Identities = 75/233 (32%), Positives = 103/233 (44%), Gaps = 54/233 (23%)
Query: 21 CICKPGYESGSE-----GALCRDVDECRDNPRV-CRR-GRCRNTAGSYTCLCEPGFAPTA 73
C C PG+ S SE C D++EC +V C + C NT GSY C+C PG+ P +
Sbjct: 42 CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 101
Query: 74 A---------GYCADVDECAAD-SMCKG-GRCVNSEGSFQCVCEAGYR--PTATRGACVD 120
C DVDEC + +CK G CVN+ GS+ C C G++ P + C D
Sbjct: 102 GTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK-VCTD 160
Query: 121 VDECEE-QRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
V+EC Q C + C N GS++C C PG+ P GS
Sbjct: 161 VNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ----------------------PIPGS 198
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHP 230
P GP+ + D++EC++ C + C N Y C C PG+ P
Sbjct: 199 -------PNGPN-NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 243
Score = 78.6 bits (185), Expect = 4e-14
Identities = 42/121 (34%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 3 NGGMCTN-GICKNIDGGFECICKPGYESGSEGA-LCRDVDECRDNPRVCRRG-RCRNTAG 59
N +C + G C N G + C C PG++ E +C DV+EC C C N G
Sbjct: 123 NPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVG 182
Query: 60 SYTCLCEPGFAPTAAG-------YCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYR 110
SY C C PG+ P C DVDEC++ C C N+ GS+ C C G++
Sbjct: 183 SYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242
Query: 111 P 111
P
Sbjct: 243 P 243
Score = 78.2 bits (184), Expect = 6e-14
Identities = 57/179 (31%), Positives = 78/179 (43%), Gaps = 40/179 (22%)
Query: 197 DINECTAVPGACPHGS---CENLEPGYRCICDPGYHP---------DADGLCRDIDECDM 244
DINEC A P G C N E Y C+C PGY P +++ C+D+DEC
Sbjct: 64 DINEC-ATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQ 122
Query: 245 HQSYCAG-GQCRNTAGSFTCVCPEGTRHEPE-LQLCRDIDECEG-----ETETHYIES-- 295
+ C G C NT GS+TC C G + PE ++C D++EC + TH + +
Sbjct: 123 NPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVG 182
Query: 296 DYERGDIP--------PTFPTRT--ELASPCDNGR--------CINTHGGFECECELGY 336
Y+ P P P T E C +G+ C NT G + C C G+
Sbjct: 183 SYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241
Score = 74.5 bits (175), Expect = 7e-13
Identities = 58/215 (26%), Positives = 84/215 (39%), Gaps = 44/215 (20%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR---CHNTP 139
C +S C F E PT T C D++EC G+ C NT
Sbjct: 30 CPQNSSCVNATACRCNPGFSSFSEIITTPTET---CDDINECATPSKVSCGKFSDCWNTE 86
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN 199
GS+ C C PG+ P G++ + +N D++
Sbjct: 87 GSYDCVCSPGYE----------------------PVSGTKTFK------NESENTCQDVD 118
Query: 200 ECTAVPGACP-HGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYC-AGGQCR 255
EC P C +G+C N Y C C PG+ P+ +C D++EC Q+ C + C
Sbjct: 119 ECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCL 178
Query: 256 NTAGSFTCVCPEGTR------HEPELQLCRDIDEC 284
N GS+ C C G + + P +C D+DEC
Sbjct: 179 NNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDEC 213
Score = 57.6 bits (133), Expect = 8e-08
Identities = 66/258 (25%), Positives = 92/258 (35%), Gaps = 45/258 (17%)
Query: 195 GADINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGL------CRDIDECDMHQS 247
GA+ + CP + SC N C C+PG+ ++ + C DI+EC
Sbjct: 17 GAETQDSRGCARWCPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSK 73
Query: 248 YCAG--GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
G C NT GS+ CVC G +EP T+T ES+ D+
Sbjct: 74 VSCGKFSDCWNTEGSYDCVCSPG--YEPV-----------SGTKTFKNESENTCQDVDEC 120
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGY-VLDATAQRCLDNRRGSCWRRVVDGQCEA 364
S G C+NT G + C+C G+ + + C D + +
Sbjct: 121 QQNPRLCKS---YGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 177
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
+ +C C G W + C DVDEC+ C
Sbjct: 178 L--NNVGSYQCRCRPG--WQPIPGSPNGP-----------NNTVCEDVDECSSGQHQCDS 222
Query: 425 GT-CVNTDGSYRCDCPPG 441
T C NT GSY C C PG
Sbjct: 223 STVCFNTVGSYSCRCRPG 240
>BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like 2 protein.
Length = 823
Score = 126 bits (305), Expect = 1e-28
Identities = 67/160 (41%), Positives = 88/160 (55%), Gaps = 21/160 (13%)
Query: 12 CKNIDGGFECICKPGYE--SGSEGA------LCRDVDECRDNPRVCRR-GRCRNTAGSYT 62
C N +G ++C+C PGYE SG++ C+DVDEC+ NPR+C+ G C NT GSYT
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 144
Query: 63 CLCEPG--FAPTAAGYCADVDEC-AADSMCKGG-RCVNSEGSFQCVCEAGYRPT------ 112
C C PG F P C DV+EC + + C C+N+ GS+QC C G++P
Sbjct: 145 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 204
Query: 113 ATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGF 150
C DVDEC Q C + C NT GS+ C C PG+
Sbjct: 205 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 96.3 bits (229), Expect = 2e-19
Identities = 75/233 (32%), Positives = 103/233 (44%), Gaps = 54/233 (23%)
Query: 21 CICKPGYESGSE-----GALCRDVDECRDNPRV-CRR-GRCRNTAGSYTCLCEPGFAPTA 73
C C PG+ S SE C D++EC +V C + C NT GSY C+C PG+ P +
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 74 A---------GYCADVDECAAD-SMCKG-GRCVNSEGSFQCVCEAGYR--PTATRGACVD 120
C DVDEC + +CK G CVN+ GS+ C C G++ P + C D
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK-VCTD 163
Query: 121 VDECEE-QRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
V+EC Q C + C N GS++C C PG+ P GS
Sbjct: 164 VNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ----------------------PIPGS 201
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHP 230
P GP+ + D++EC++ C + C N Y C C PG+ P
Sbjct: 202 -------PNGPN-NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Score = 78.6 bits (185), Expect = 4e-14
Identities = 42/121 (34%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 3 NGGMCTN-GICKNIDGGFECICKPGYESGSEGA-LCRDVDECRDNPRVCRRG-RCRNTAG 59
N +C + G C N G + C C PG++ E +C DV+EC C C N G
Sbjct: 126 NPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVG 185
Query: 60 SYTCLCEPGFAPTAAG-------YCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYR 110
SY C C PG+ P C DVDEC++ C C N+ GS+ C C G++
Sbjct: 186 SYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Query: 111 P 111
P
Sbjct: 246 P 246
Score = 77.8 bits (183), Expect = 7e-14
Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 38/178 (21%)
Query: 197 DINECTAVPG-ACPHGS-CENLEPGYRCICDPGYHP---------DADGLCRDIDECDMH 245
DINEC + +C S C N E Y C+C PGY P +++ C+D+DEC +
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 246 QSYCAG-GQCRNTAGSFTCVCPEGTRHEPE-LQLCRDIDECEG-----ETETHYIES--D 296
C G C NT GS+TC C G + PE ++C D++EC + TH + +
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 297 YERGDIP--------PTFPTRT--ELASPCDNGR--------CINTHGGFECECELGY 336
Y+ P P P T E C +G+ C NT G + C C G+
Sbjct: 187 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 73.7 bits (173), Expect = 1e-12
Identities = 58/215 (26%), Positives = 83/215 (38%), Gaps = 44/215 (20%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR---CHNTP 139
C DS C F E P T C D++EC G+ C NT
Sbjct: 33 CPQDSSCVNATACRCNPGFSSFSEIITTPMET---CDDINECATLSKVSCGKFSDCWNTE 89
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN 199
GS+ C C PG+ P G++ + +N D++
Sbjct: 90 GSYDCVCSPGYE----------------------PVSGAKTFK------NESENTCQDVD 121
Query: 200 ECTAVPGACP-HGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYC-AGGQCR 255
EC P C +G+C N Y C C PG+ P+ +C D++EC Q+ C + C
Sbjct: 122 ECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCL 181
Query: 256 NTAGSFTCVCPEGTR------HEPELQLCRDIDEC 284
N GS+ C C G + + P +C D+DEC
Sbjct: 182 NNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDEC 216
Score = 54.8 bits (126), Expect = 6e-07
Identities = 65/258 (25%), Positives = 90/258 (34%), Gaps = 45/258 (17%)
Query: 195 GADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL------CRDIDECDMHQS 247
GA+ + CP SC N C C+PG+ ++ + C DI+EC
Sbjct: 20 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 76
Query: 248 YCAG--GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
G C NT GS+ CVC G +EP +T ES+ D+
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPG--YEPV-----------SGAKTFKNESENTCQDVDEC 123
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGY-VLDATAQRCLDNRRGSCWRRVVDGQCEA 364
S G C+NT G + C+C G+ + + C D + +
Sbjct: 124 QQNPRLCKS---YGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 180
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
+ +C C G W + C DVDEC+ C
Sbjct: 181 L--NNVGSYQCRCRPG--WQPIPGSPNGP-----------NNTVCEDVDECSSGQHQCDS 225
Query: 425 GT-CVNTDGSYRCDCPPG 441
T C NT GSY C C PG
Sbjct: 226 STVCFNTVGSYSCRCRPG 243
>BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like 2 protein.
Length = 823
Score = 126 bits (305), Expect = 1e-28
Identities = 67/160 (41%), Positives = 88/160 (55%), Gaps = 21/160 (13%)
Query: 12 CKNIDGGFECICKPGYE--SGSEGA------LCRDVDECRDNPRVCRR-GRCRNTAGSYT 62
C N +G ++C+C PGYE SG++ C+DVDEC+ NPR+C+ G C NT GSYT
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 144
Query: 63 CLCEPG--FAPTAAGYCADVDEC-AADSMCKGG-RCVNSEGSFQCVCEAGYRPT------ 112
C C PG F P C DV+EC + + C C+N+ GS+QC C G++P
Sbjct: 145 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 204
Query: 113 ATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGF 150
C DVDEC Q C + C NT GS+ C C PG+
Sbjct: 205 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 96.3 bits (229), Expect = 2e-19
Identities = 75/233 (32%), Positives = 103/233 (44%), Gaps = 54/233 (23%)
Query: 21 CICKPGYESGSE-----GALCRDVDECRDNPRV-CRR-GRCRNTAGSYTCLCEPGFAPTA 73
C C PG+ S SE C D++EC +V C + C NT GSY C+C PG+ P +
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 74 A---------GYCADVDECAAD-SMCKG-GRCVNSEGSFQCVCEAGYR--PTATRGACVD 120
C DVDEC + +CK G CVN+ GS+ C C G++ P + C D
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK-VCTD 163
Query: 121 VDECEE-QRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
V+EC Q C + C N GS++C C PG+ P GS
Sbjct: 164 VNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ----------------------PIPGS 201
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHP 230
P GP+ + D++EC++ C + C N Y C C PG+ P
Sbjct: 202 -------PNGPN-NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Score = 78.6 bits (185), Expect = 4e-14
Identities = 42/121 (34%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 3 NGGMCTN-GICKNIDGGFECICKPGYESGSEGA-LCRDVDECRDNPRVCRRG-RCRNTAG 59
N +C + G C N G + C C PG++ E +C DV+EC C C N G
Sbjct: 126 NPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVG 185
Query: 60 SYTCLCEPGFAPTAAG-------YCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYR 110
SY C C PG+ P C DVDEC++ C C N+ GS+ C C G++
Sbjct: 186 SYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Query: 111 P 111
P
Sbjct: 246 P 246
Score = 77.8 bits (183), Expect = 7e-14
Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 38/178 (21%)
Query: 197 DINECTAVPG-ACPHGS-CENLEPGYRCICDPGYHP---------DADGLCRDIDECDMH 245
DINEC + +C S C N E Y C+C PGY P +++ C+D+DEC +
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 246 QSYCAG-GQCRNTAGSFTCVCPEGTRHEPE-LQLCRDIDECEG-----ETETHYIES--D 296
C G C NT GS+TC C G + PE ++C D++EC + TH + +
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 297 YERGDIP--------PTFPTRT--ELASPCDNGR--------CINTHGGFECECELGY 336
Y+ P P P T E C +G+ C NT G + C C G+
Sbjct: 187 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 73.7 bits (173), Expect = 1e-12
Identities = 58/215 (26%), Positives = 83/215 (38%), Gaps = 44/215 (20%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR---CHNTP 139
C DS C F E P T C D++EC G+ C NT
Sbjct: 33 CPQDSSCVNATACRCNPGFSSFSEIITTPMET---CDDINECATLSKVSCGKFSDCWNTE 89
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN 199
GS+ C C PG+ P G++ + +N D++
Sbjct: 90 GSYDCVCSPGYE----------------------PVSGAKTFK------NESENTCQDVD 121
Query: 200 ECTAVPGACP-HGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYC-AGGQCR 255
EC P C +G+C N Y C C PG+ P+ +C D++EC Q+ C + C
Sbjct: 122 ECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCL 181
Query: 256 NTAGSFTCVCPEGTR------HEPELQLCRDIDEC 284
N GS+ C C G + + P +C D+DEC
Sbjct: 182 NNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDEC 216
Score = 54.8 bits (126), Expect = 6e-07
Identities = 65/258 (25%), Positives = 90/258 (34%), Gaps = 45/258 (17%)
Query: 195 GADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL------CRDIDECDMHQS 247
GA+ + CP SC N C C+PG+ ++ + C DI+EC
Sbjct: 20 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 76
Query: 248 YCAG--GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
G C NT GS+ CVC G +EP +T ES+ D+
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPG--YEPV-----------SGAKTFKNESENTCQDVDEC 123
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGY-VLDATAQRCLDNRRGSCWRRVVDGQCEA 364
S G C+NT G + C+C G+ + + C D + +
Sbjct: 124 QQNPRLCKS---YGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 180
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
+ +C C G W + C DVDEC+ C
Sbjct: 181 L--NNVGSYQCRCRPG--WQPIPGSPNGP-----------NNTVCEDVDECSSGQHQCDS 225
Query: 425 GT-CVNTDGSYRCDCPPG 441
T C NT GSY C C PG
Sbjct: 226 STVCFNTVGSYSCRCRPG 243
>AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like sequence 2
isofor protein.
Length = 810
Score = 126 bits (305), Expect = 1e-28
Identities = 67/160 (41%), Positives = 88/160 (55%), Gaps = 21/160 (13%)
Query: 12 CKNIDGGFECICKPGYE--SGSEGA------LCRDVDECRDNPRVCRR-GRCRNTAGSYT 62
C N +G ++C+C PGYE SG++ C+DVDEC+ NPR+C+ G C NT GSYT
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 144
Query: 63 CLCEPGF--APTAAGYCADVDEC-AADSMCKGG-RCVNSEGSFQCVCEAGYRPT------ 112
C C PGF P C DV+EC + + C C+N+ GS+QC C G++P
Sbjct: 145 CQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 204
Query: 113 ATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGF 150
C DVDEC Q C + C NT GS+ C C PG+
Sbjct: 205 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 95.9 bits (228), Expect = 3e-19
Identities = 74/232 (31%), Positives = 101/232 (43%), Gaps = 52/232 (22%)
Query: 21 CICKPGYESGSE-----GALCRDVDECRDNPRV-CRR-GRCRNTAGSYTCLCEPGFAPTA 73
C C PG+ S SE C D++EC +V C + C NT GSY C+C PG+ P +
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 74 A---------GYCADVDECAAD-SMCKG-GRCVNSEGSFQCVCEAGYR-PTATRGACVDV 121
C DVDEC + +CK G CVN+ GS+ C C G++ C DV
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDV 164
Query: 122 DECEE-QRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
+EC Q C + C N GS++C C PG+ P GS
Sbjct: 165 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ----------------------PIPGS- 201
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHP 230
P GP+ + D++EC++ C + C N Y C C PG+ P
Sbjct: 202 ------PNGPN-NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Score = 87.4 bits (207), Expect = 9e-17
Identities = 76/225 (33%), Positives = 97/225 (43%), Gaps = 45/225 (20%)
Query: 63 CLCEPGFAP------TAAGYCADVDECAADSMCKGGR---CVNSEGSFQCVCEAGYRPTA 113
C C PGF+ T C D++ECA S G+ C N+EGS+ CVC GY P +
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQAC 173
GA +E E C + EC L TC+ LG +CQ
Sbjct: 105 --GAKTFKNESENT-------CQDVD-----ECQQNPRLCKSYGTCVNT-LG-SYTCQCL 148
Query: 174 PAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS--CENLEPGYRCICDPGYHP- 230
P G +L PE P D+NECT+ C H S C N Y+C C PG+ P
Sbjct: 149 P--GFKLK----PEDPKLCT---DVNECTSGQNPC-HSSTHCLNNVGSYQCRCRPGWQPI 198
Query: 231 --DADG----LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEG 268
+G +C D+DEC Q C C NT GS++C C G
Sbjct: 199 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 243
Score = 80.6 bits (190), Expect = 1e-14
Identities = 43/121 (35%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 3 NGGMCTN-GICKNIDGGFECICKPGYESGSEGA-LCRDVDECRDNPRVCRRG-RCRNTAG 59
N +C + G C N G + C C PG++ E LC DV+EC C C N G
Sbjct: 126 NPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVG 185
Query: 60 SYTCLCEPGFAPTAAG-------YCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYR 110
SY C C PG+ P C DVDEC++ C C N+ GS+ C C G++
Sbjct: 186 SYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Query: 111 P 111
P
Sbjct: 246 P 246
Score = 79.8 bits (188), Expect = 2e-14
Identities = 57/178 (32%), Positives = 80/178 (44%), Gaps = 38/178 (21%)
Query: 197 DINECTAVPG-ACPHGS-CENLEPGYRCICDPGYHP---------DADGLCRDIDECDMH 245
DINEC + +C S C N E Y C+C PGY P +++ C+D+DEC +
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 246 QSYCAG-GQCRNTAGSFTCVCPEGTRHEPE-LQLCRDIDECEG-----ETETHYIES--D 296
C G C NT GS+TC C G + +PE +LC D++EC + TH + +
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 297 YERGDIP--------PTFPTRT--ELASPCDNGR--------CINTHGGFECECELGY 336
Y+ P P P T E C +G+ C NT G + C C G+
Sbjct: 187 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 74.9 bits (176), Expect = 5e-13
Identities = 59/215 (27%), Positives = 83/215 (38%), Gaps = 44/215 (20%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR---CHNTP 139
C DS C F E P T C D++EC G+ C NT
Sbjct: 33 CPQDSSCVNATACRCNPGFSSFSEIITTPMET---CDDINECATLSKVSCGKFSDCWNTE 89
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN 199
GS+ C C PG+ P G++ + +N D++
Sbjct: 90 GSYDCVCSPGYE----------------------PVSGAKTFK------NESENTCQDVD 121
Query: 200 ECTAVPGACP-HGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYC-AGGQCR 255
EC P C +G+C N Y C C PG+ P+ LC D++EC Q+ C + C
Sbjct: 122 ECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCL 181
Query: 256 NTAGSFTCVCPEGTR------HEPELQLCRDIDEC 284
N GS+ C C G + + P +C D+DEC
Sbjct: 182 NNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDEC 216
Score = 56.0 bits (129), Expect = 3e-07
Identities = 66/258 (25%), Positives = 90/258 (34%), Gaps = 45/258 (17%)
Query: 195 GADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL------CRDIDECDMHQS 247
GA+ + CP SC N C C+PG+ ++ + C DI+EC
Sbjct: 20 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 76
Query: 248 YCAG--GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
G C NT GS+ CVC G +EP +T ES+ D+
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPG--YEPV-----------SGAKTFKNESENTCQDVDEC 123
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQR-CLDNRRGSCWRRVVDGQCEA 364
S G C+NT G + C+C G+ L + C D + +
Sbjct: 124 QQNPRLCKS---YGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 180
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
+ +C C G W + C DVDEC+ C
Sbjct: 181 L--NNVGSYQCRCRPG--WQPIPGSPNGP-----------NNTVCEDVDECSSGQHQCDS 225
Query: 425 GT-CVNTDGSYRCDCPPG 441
T C NT GSY C C PG
Sbjct: 226 STVCFNTVGSYSCRCRPG 243
Score = 53.2 bits (122), Expect = 2e-06
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 399 KGFAKLDGATCRDVDECALSAELCAG-GTCVNTDGSYRCDCPPGLTL 444
K F TC+DVDEC + LC GTCVNT GSY C C PG L
Sbjct: 107 KTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKL 153
>AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2
protein.
Length = 823
Score = 126 bits (305), Expect = 1e-28
Identities = 67/160 (41%), Positives = 88/160 (55%), Gaps = 21/160 (13%)
Query: 12 CKNIDGGFECICKPGYE--SGSEGA------LCRDVDECRDNPRVCRR-GRCRNTAGSYT 62
C N +G ++C+C PGYE SG++ C+DVDEC+ NPR+C+ G C NT GSYT
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 144
Query: 63 CLCEPGF--APTAAGYCADVDEC-AADSMCKGG-RCVNSEGSFQCVCEAGYRPT------ 112
C C PGF P C DV+EC + + C C+N+ GS+QC C G++P
Sbjct: 145 CQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 204
Query: 113 ATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGF 150
C DVDEC Q C + C NT GS+ C C PG+
Sbjct: 205 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 95.9 bits (228), Expect = 3e-19
Identities = 74/232 (31%), Positives = 101/232 (43%), Gaps = 52/232 (22%)
Query: 21 CICKPGYESGSE-----GALCRDVDECRDNPRV-CRR-GRCRNTAGSYTCLCEPGFAPTA 73
C C PG+ S SE C D++EC +V C + C NT GSY C+C PG+ P +
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 74 A---------GYCADVDECAAD-SMCKG-GRCVNSEGSFQCVCEAGYR-PTATRGACVDV 121
C DVDEC + +CK G CVN+ GS+ C C G++ C DV
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDV 164
Query: 122 DECEE-QRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
+EC Q C + C N GS++C C PG+ P GS
Sbjct: 165 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ----------------------PIPGS- 201
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHP 230
P GP+ + D++EC++ C + C N Y C C PG+ P
Sbjct: 202 ------PNGPN-NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 246
Score = 87.4 bits (207), Expect = 9e-17
Identities = 76/225 (33%), Positives = 97/225 (43%), Gaps = 45/225 (20%)
Query: 63 CLCEPGFAP------TAAGYCADVDECAADSMCKGGR---CVNSEGSFQCVCEAGYRPTA 113
C C PGF+ T C D++ECA S G+ C N+EGS+ CVC GY P +
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 114 TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQAC 173
GA +E E C + EC L TC+ LG +CQ
Sbjct: 105 --GAKTFKNESENT-------CQDVD-----ECQQNPRLCKSYGTCVNT-LG-SYTCQCL 148
Query: 174 PAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS--CENLEPGYRCICDPGYHP- 230
P G +L PE P D+NECT+ C H S C N Y+C C PG+ P
Sbjct: 149 P--GFKLK----PEDPKLCT---DVNECTSGQNPC-HSSTHCLNNVGSYQCRCRPGWQPI 198
Query: 231 --DADG----LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEG 268
+G +C D+DEC Q C C NT GS++C C G
Sbjct: 199 PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 243
Score = 80.6 bits (190), Expect = 1e-14
Identities = 43/121 (35%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 3 NGGMCTN-GICKNIDGGFECICKPGYESGSEGA-LCRDVDECRDNPRVCRRG-RCRNTAG 59
N +C + G C N G + C C PG++ E LC DV+EC C C N G
Sbjct: 126 NPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVG 185
Query: 60 SYTCLCEPGFAPTAAG-------YCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYR 110
SY C C PG+ P C DVDEC++ C C N+ GS+ C C G++
Sbjct: 186 SYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Query: 111 P 111
P
Sbjct: 246 P 246
Score = 79.8 bits (188), Expect = 2e-14
Identities = 57/178 (32%), Positives = 80/178 (44%), Gaps = 38/178 (21%)
Query: 197 DINECTAVPG-ACPHGS-CENLEPGYRCICDPGYHP---------DADGLCRDIDECDMH 245
DINEC + +C S C N E Y C+C PGY P +++ C+D+DEC +
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 246 QSYCAG-GQCRNTAGSFTCVCPEGTRHEPE-LQLCRDIDECEG-----ETETHYIES--D 296
C G C NT GS+TC C G + +PE +LC D++EC + TH + +
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGS 186
Query: 297 YERGDIP--------PTFPTRT--ELASPCDNGR--------CINTHGGFECECELGY 336
Y+ P P P T E C +G+ C NT G + C C G+
Sbjct: 187 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 244
Score = 74.9 bits (176), Expect = 5e-13
Identities = 59/215 (27%), Positives = 83/215 (38%), Gaps = 44/215 (20%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR---CHNTP 139
C DS C F E P T C D++EC G+ C NT
Sbjct: 33 CPQDSSCVNATACRCNPGFSSFSEIITTPMET---CDDINECATLSKVSCGKFSDCWNTE 89
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN 199
GS+ C C PG+ P G++ + +N D++
Sbjct: 90 GSYDCVCSPGYE----------------------PVSGAKTFK------NESENTCQDVD 121
Query: 200 ECTAVPGACP-HGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYC-AGGQCR 255
EC P C +G+C N Y C C PG+ P+ LC D++EC Q+ C + C
Sbjct: 122 ECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCL 181
Query: 256 NTAGSFTCVCPEGTR------HEPELQLCRDIDEC 284
N GS+ C C G + + P +C D+DEC
Sbjct: 182 NNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDEC 216
Score = 56.0 bits (129), Expect = 3e-07
Identities = 66/258 (25%), Positives = 90/258 (34%), Gaps = 45/258 (17%)
Query: 195 GADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL------CRDIDECDMHQS 247
GA+ + CP SC N C C+PG+ ++ + C DI+EC
Sbjct: 20 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 76
Query: 248 YCAG--GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
G C NT GS+ CVC G +EP +T ES+ D+
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPG--YEPV-----------SGAKTFKNESENTCQDVDEC 123
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQR-CLDNRRGSCWRRVVDGQCEA 364
S G C+NT G + C+C G+ L + C D + +
Sbjct: 124 QQNPRLCKS---YGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 180
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
+ +C C G W + C DVDEC+ C
Sbjct: 181 L--NNVGSYQCRCRPG--WQPIPGSPNGP-----------NNTVCEDVDECSSGQHQCDS 225
Query: 425 GT-CVNTDGSYRCDCPPG 441
T C NT GSY C C PG
Sbjct: 226 STVCFNTVGSYSCRCRPG 243
Score = 53.2 bits (122), Expect = 2e-06
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 399 KGFAKLDGATCRDVDECALSAELCAG-GTCVNTDGSYRCDCPPGLTL 444
K F TC+DVDEC + LC GTCVNT GSY C C PG L
Sbjct: 107 KTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKL 153
>AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane helix
receptor protein.
Length = 837
Score = 126 bits (305), Expect = 1e-28
Identities = 67/160 (41%), Positives = 88/160 (55%), Gaps = 21/160 (13%)
Query: 12 CKNIDGGFECICKPGYE--SGSEGA------LCRDVDECRDNPRVCRR-GRCRNTAGSYT 62
C N +G ++C+C PGYE SG++ C+DVDEC+ NPR+C+ G C NT GSYT
Sbjct: 84 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 143
Query: 63 CLCEPG--FAPTAAGYCADVDEC-AADSMCKGG-RCVNSEGSFQCVCEAGYRPT------ 112
C C PG F P C DV+EC + + C C+N+ GS+QC C G++P
Sbjct: 144 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 203
Query: 113 ATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGF 150
C DVDEC Q C + C NT GS+ C C PG+
Sbjct: 204 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 243
Score = 97.1 bits (231), Expect = 1e-19
Identities = 75/233 (32%), Positives = 103/233 (44%), Gaps = 54/233 (23%)
Query: 21 CICKPGYESGSE-----GALCRDVDECRDNPRV-CRR-GRCRNTAGSYTCLCEPGFAPTA 73
C C PG+ S SE C D++EC +V C + C NT GSY C+C PG+ P +
Sbjct: 44 CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 103
Query: 74 A---------GYCADVDECAAD-SMCKG-GRCVNSEGSFQCVCEAGYR--PTATRGACVD 120
C DVDEC + +CK G CVN+ GS+ C C G++ P + C D
Sbjct: 104 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK-VCTD 162
Query: 121 VDECEE-QRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
V+EC Q C + C N GS++C C PG+ P GS
Sbjct: 163 VNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ----------------------PIPGS 200
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHP 230
P GP+ + D++EC++ C + C N Y C C PG+ P
Sbjct: 201 -------PNGPN-NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 245
Score = 78.6 bits (185), Expect = 4e-14
Identities = 42/121 (34%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 3 NGGMCTN-GICKNIDGGFECICKPGYESGSEGA-LCRDVDECRDNPRVCRRG-RCRNTAG 59
N +C + G C N G + C C PG++ E +C DV+EC C C N G
Sbjct: 125 NPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVG 184
Query: 60 SYTCLCEPGFAPTAAG-------YCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYR 110
SY C C PG+ P C DVDEC++ C C N+ GS+ C C G++
Sbjct: 185 SYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 244
Query: 111 P 111
P
Sbjct: 245 P 245
Score = 78.2 bits (184), Expect = 6e-14
Identities = 57/179 (31%), Positives = 78/179 (43%), Gaps = 40/179 (22%)
Query: 197 DINECTAVPGACPHGS---CENLEPGYRCICDPGYHP---------DADGLCRDIDECDM 244
DINEC A P G C N E Y C+C PGY P +++ C+D+DEC
Sbjct: 66 DINEC-ATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQ 124
Query: 245 HQSYCAG-GQCRNTAGSFTCVCPEGTRHEPE-LQLCRDIDECEG-----ETETHYIES-- 295
+ C G C NT GS+TC C G + PE ++C D++EC + TH + +
Sbjct: 125 NPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVG 184
Query: 296 DYERGDIP--------PTFPTRT--ELASPCDNGR--------CINTHGGFECECELGY 336
Y+ P P P T E C +G+ C NT G + C C G+
Sbjct: 185 SYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 243
Score = 74.5 bits (175), Expect = 7e-13
Identities = 58/215 (26%), Positives = 84/215 (39%), Gaps = 44/215 (20%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR---CHNTP 139
C +S C F E PT T C D++EC G+ C NT
Sbjct: 32 CPQNSSCVNATACRCNPGFSSFSEIITTPTET---CDDINECATPSKVSCGKFSDCWNTE 88
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN 199
GS+ C C PG+ P G++ + +N D++
Sbjct: 89 GSYDCVCSPGYE----------------------PVSGAKTFK------NESENTCQDVD 120
Query: 200 ECTAVPGACP-HGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYC-AGGQCR 255
EC P C +G+C N Y C C PG+ P+ +C D++EC Q+ C + C
Sbjct: 121 ECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCL 180
Query: 256 NTAGSFTCVCPEGTR------HEPELQLCRDIDEC 284
N GS+ C C G + + P +C D+DEC
Sbjct: 181 NNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDEC 215
Score = 55.6 bits (128), Expect = 3e-07
Identities = 65/258 (25%), Positives = 91/258 (35%), Gaps = 45/258 (17%)
Query: 195 GADINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGL------CRDIDECDMHQS 247
GA+ + CP + SC N C C+PG+ ++ + C DI+EC
Sbjct: 19 GAETQDSRGCARWCPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSK 75
Query: 248 YCAG--GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
G C NT GS+ CVC G +EP +T ES+ D+
Sbjct: 76 VSCGKFSDCWNTEGSYDCVCSPG--YEPV-----------SGAKTFKNESENTCQDVDEC 122
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGY-VLDATAQRCLDNRRGSCWRRVVDGQCEA 364
S G C+NT G + C+C G+ + + C D + +
Sbjct: 123 QQNPRLCKS---YGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 179
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
+ +C C G W + C DVDEC+ C
Sbjct: 180 L--NNVGSYQCRCRPG--WQPIPGSPNGP-----------NNTVCEDVDECSSGQHQCDS 224
Query: 425 GT-CVNTDGSYRCDCPPG 441
T C NT GSY C C PG
Sbjct: 225 STVCFNTVGSYSCRCRPG 242
>AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane helix
receptor protein.
Length = 837
Score = 126 bits (305), Expect = 1e-28
Identities = 67/160 (41%), Positives = 88/160 (55%), Gaps = 21/160 (13%)
Query: 12 CKNIDGGFECICKPGYE--SGSE------GALCRDVDECRDNPRVCRR-GRCRNTAGSYT 62
C N +G ++C+C PGYE SG++ C+DVDEC+ NPR+C+ G C NT GSYT
Sbjct: 86 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 145
Query: 63 CLCEPGF--APTAAGYCADVDEC-AADSMCKGG-RCVNSEGSFQCVCEAGYRPT------ 112
C C PGF P C DV+EC + + C C+N+ GS+QC C G++P
Sbjct: 146 CQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 205
Query: 113 ATRGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGF 150
C DVDEC Q C + C NT GS+ C C PG+
Sbjct: 206 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 245
Score = 95.9 bits (228), Expect = 3e-19
Identities = 74/232 (31%), Positives = 101/232 (43%), Gaps = 52/232 (22%)
Query: 21 CICKPGYESGSE-----GALCRDVDECRDNPRV-CRR-GRCRNTAGSYTCLCEPGFAPTA 73
C C PG+ S SE C D++EC +V C + C NT GSY C+C PG+ P +
Sbjct: 46 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 105
Query: 74 A---------GYCADVDECAAD-SMCKG-GRCVNSEGSFQCVCEAGYR-PTATRGACVDV 121
C DVDEC + +CK G CVN+ GS+ C C G++ C DV
Sbjct: 106 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDV 165
Query: 122 DECEE-QRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
+EC Q C + C N GS++C C PG+ P GS
Sbjct: 166 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ----------------------PIPGS- 202
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHP 230
P GP+ + D++EC++ C + C N Y C C PG+ P
Sbjct: 203 ------PNGPN-NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 247
Score = 87.8 bits (208), Expect = 7e-17
Identities = 85/267 (31%), Positives = 113/267 (42%), Gaps = 48/267 (17%)
Query: 23 CKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTA--GSYTCLCEPGFAP------TAA 74
C P Y L E +D+ R C R ++++ + C C PGF+ T
Sbjct: 5 CSPSYLGAFCVWLTLPGAETQDS-RGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPM 63
Query: 75 GYCADVDECAADSMCKGGR---CVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCR 131
C D++ECA S G+ C N+EGS+ CVC GY P + GA +E E
Sbjct: 64 ETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS--GAKTFKNESENT---- 117
Query: 132 NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
C + EC L TC+ LG +CQ P G +L PE P
Sbjct: 118 ---CQDVD-----ECQQNPRLCKSYGTCVNT-LG-SYTCQCLP--GFKLK----PEDPKL 161
Query: 192 DNGGADINECTAVPGACPHGS--CENLEPGYRCICDPGYHP---DADG----LCRDIDEC 242
D+NECT+ C H S C N Y+C C PG+ P +G +C D+DEC
Sbjct: 162 CT---DVNECTSGQNPC-HSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDEC 217
Query: 243 DMHQSYCAGGQ-CRNTAGSFTCVCPEG 268
Q C C NT GS++C C G
Sbjct: 218 SSGQHQCDSSTVCFNTVGSYSCRCRPG 244
Score = 80.6 bits (190), Expect = 1e-14
Identities = 43/121 (35%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 3 NGGMCTN-GICKNIDGGFECICKPGYESGSEGA-LCRDVDECRDNPRVCRRG-RCRNTAG 59
N +C + G C N G + C C PG++ E LC DV+EC C C N G
Sbjct: 127 NPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVG 186
Query: 60 SYTCLCEPGFAPTAAG-------YCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYR 110
SY C C PG+ P C DVDEC++ C C N+ GS+ C C G++
Sbjct: 187 SYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 246
Query: 111 P 111
P
Sbjct: 247 P 247
Score = 79.8 bits (188), Expect = 2e-14
Identities = 57/178 (32%), Positives = 80/178 (44%), Gaps = 38/178 (21%)
Query: 197 DINECTAVPG-ACPHGS-CENLEPGYRCICDPGYHP---------DADGLCRDIDECDMH 245
DINEC + +C S C N E Y C+C PGY P +++ C+D+DEC +
Sbjct: 68 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 127
Query: 246 QSYCAG-GQCRNTAGSFTCVCPEGTRHEPE-LQLCRDIDECEG-----ETETHYIES--D 296
C G C NT GS+TC C G + +PE +LC D++EC + TH + +
Sbjct: 128 PRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGS 187
Query: 297 YERGDIP--------PTFPTRT--ELASPCDNGR--------CINTHGGFECECELGY 336
Y+ P P P T E C +G+ C NT G + C C G+
Sbjct: 188 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 245
Score = 74.9 bits (176), Expect = 5e-13
Identities = 59/215 (27%), Positives = 83/215 (38%), Gaps = 44/215 (20%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR---CHNTP 139
C DS C F E P T C D++EC G+ C NT
Sbjct: 34 CPQDSSCVNATACRCNPGFSSFSEIITTPMET---CDDINECATLSKVSCGKFSDCWNTE 90
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN 199
GS+ C C PG+ P G++ + +N D++
Sbjct: 91 GSYDCVCSPGYE----------------------PVSGAKTFK------NESENTCQDVD 122
Query: 200 ECTAVPGACP-HGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYC-AGGQCR 255
EC P C +G+C N Y C C PG+ P+ LC D++EC Q+ C + C
Sbjct: 123 ECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCL 182
Query: 256 NTAGSFTCVCPEGTR------HEPELQLCRDIDEC 284
N GS+ C C G + + P +C D+DEC
Sbjct: 183 NNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDEC 217
Score = 56.0 bits (129), Expect = 3e-07
Identities = 66/258 (25%), Positives = 90/258 (34%), Gaps = 45/258 (17%)
Query: 195 GADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL------CRDIDECDMHQS 247
GA+ + CP SC N C C+PG+ ++ + C DI+EC
Sbjct: 21 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 77
Query: 248 YCAG--GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
G C NT GS+ CVC G +EP +T ES+ D+
Sbjct: 78 VSCGKFSDCWNTEGSYDCVCSPG--YEPV-----------SGAKTFKNESENTCQDVDEC 124
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQR-CLDNRRGSCWRRVVDGQCEA 364
S G C+NT G + C+C G+ L + C D + +
Sbjct: 125 QQNPRLCKS---YGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 181
Query: 365 AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAG 424
+ +C C G W + C DVDEC+ C
Sbjct: 182 L--NNVGSYQCRCRPG--WQPIPGSPNGP-----------NNTVCEDVDECSSGQHQCDS 226
Query: 425 GT-CVNTDGSYRCDCPPG 441
T C NT GSY C C PG
Sbjct: 227 STVCFNTVGSYSCRCRPG 244
Score = 53.2 bits (122), Expect = 2e-06
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 399 KGFAKLDGATCRDVDECALSAELCAG-GTCVNTDGSYRCDCPPGLTL 444
K F TC+DVDEC + LC GTCVNT GSY C C PG L
Sbjct: 108 KTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKL 154
>AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein.
Length = 1176
Score = 125 bits (302), Expect = 3e-28
Identities = 93/302 (30%), Positives = 128/302 (42%), Gaps = 51/302 (16%)
Query: 18 GFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAG 75
GF C C PG++ G C D+DEC P C G CRN A Y C C G+A
Sbjct: 91 GFRCYCVPGFQ----GPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYAGVTCE 144
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRC 135
+VDECA+ G C++ GSF+CVC GY T + +D+DEC+ Q G C
Sbjct: 145 --TEVDECASAPCLHGASCLDGVGSFRCVCAPGYGGTRCQ---LDLDECQSQPCAHGGTC 199
Query: 136 HNTPGSFRCECL----PGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
H+ FRC+C G + C SC +G + LC G S
Sbjct: 200 HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASC----LEGLGSFRCLCWPGYSG 255
Query: 192 DNGGADINECTAVPGACPHGS-C-ENLEP--------------------GYRCICDPGYH 229
+ D +EC + P C HG C + +P G+ C C PG+
Sbjct: 256 ELCEVDEDECASSP--CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFE 313
Query: 230 PDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE 289
G+ ++DEC + GG C++ F C CP+G P + D+DEC +
Sbjct: 314 GADCGV--EVDEC-ASRPCLNGGHCQDLPNGFQCHCPDGYA-GPTCE--EDVDECLSDPC 367
Query: 290 TH 291
H
Sbjct: 368 LH 369
Score = 114 bits (275), Expect = 5e-25
Identities = 89/287 (31%), Positives = 122/287 (42%), Gaps = 43/287 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTC 63
C +G C+N+ +EC C GY G C +VDEC P C G C + GS+ C
Sbjct: 117 CHHGATCRNLADRYECHCPLGYA----GVTCETEVDECASAP--CLHGASCLDGVGSFRC 170
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEA-GYRPTATRGACVDVD 122
+C PG+ T D+DEC + GG C + F+C C GY T +V
Sbjct: 171 VCAPGYGGTRCQL--DLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCER---EVL 225
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLKLGWGVSC--QACPAQG 177
EC N C GSFRC C PG++ D C G C ++ PA
Sbjct: 226 ECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALY 285
Query: 178 SELYAVL---------------CPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYR 221
+ A CP G + G +++EC + P C +G C++L G++
Sbjct: 286 GGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRP--CLNGGHCQDLPNGFQ 343
Query: 222 CICDPGYHPDADGLCR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
C C GY A C D+DEC + GG C +T + C CPE
Sbjct: 344 CHCPDGY---AGPTCEEDVDEC-LSDPCLHGGTCSDTVAGYICRCPE 386
Score = 76.2 bits (179), Expect = 2e-13
Identities = 66/208 (31%), Positives = 77/208 (37%), Gaps = 41/208 (19%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RC------------ 54
N C G F C+C PGY G LC D DEC +P C+ G RC
Sbjct: 235 NASCLEGLGSFRCLCWPGYS----GELCEVDEDECASSP--CQHGGRCLQRSDPALYGGV 288
Query: 55 ----------RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCV 104
R+ AG + C C PGF G +VDECA+ GG C + FQC
Sbjct: 289 QAAFPGAFSFRHAAG-FLCHCPPGFEGADCG--VEVDECASRPCLNGGHCQDLPNGFQCH 345
Query: 105 CEAGYR-PTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCL 160
C GY PT DVDEC G C +T + C C G S C
Sbjct: 346 CPDGYAGPTCEE----DVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQ 401
Query: 161 GLKLGWGVSCQACPAQGSELYAVLCPEG 188
G +C G Y CP G
Sbjct: 402 GHTCPLAATCIPIFESGVHSYVCHCPPG 429
Score = 70.5 bits (165), Expect = 1e-11
Identities = 61/205 (29%), Positives = 81/205 (39%), Gaps = 28/205 (13%)
Query: 83 CAADSMCKGGRCVNSE-GSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
CA+D G C +E G + C P RG C +C P
Sbjct: 42 CASDPCAPGTECQATESGGYTC------GPMEPRGCATQ--PCHHGALCVPQG--PDPNG 91
Query: 142 FRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADI 198
FRC C+PGF D C G +C+ ++ Y CP G + ++
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNL----ADRYECHCPLGYAGVTCETEV 147
Query: 199 NECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNT 257
+EC + P C HG SC + +RC+C PGY L D+DEC Q GG C +
Sbjct: 148 DECASAP--CLHGASCLDGVGSFRCVCAPGYGGTRCQL--DLDEC-QSQPCAHGGTCHDL 202
Query: 258 AGSFTCVCP----EGTRHEPELQLC 278
F C C EGT E E+ C
Sbjct: 203 VNGFRCDCAGTGYEGTHCEREVLEC 227
Score = 67.7 bits (158), Expect = 8e-11
Identities = 97/339 (28%), Positives = 130/339 (38%), Gaps = 48/339 (14%)
Query: 125 EEQRVCRNGRCHNTPGSFRCECLP--GFTLSN-DGRTCLGLKLGWGVSC--QACPAQGSE 179
E C + C PG+ C+ G+T + R C G C Q G
Sbjct: 37 EPPSACASDPC--APGT-ECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPNGFR 93
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR- 237
Y V +GP + DI+EC + P C HG+ C NL Y C C GY A C
Sbjct: 94 CYCVPGFQGPRCE---LDIDECASRP--CHHGATCRNLADRYECHCPLGY---AGVTCET 145
Query: 238 DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEG---TRHEPELQLCRDIDECEGETETHYI 293
++DEC + C G C + GSF CVC G TR + +L C+ G T H +
Sbjct: 146 EVDECA--SAPCLHGASCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGT-CHDL 202
Query: 294 ESDYERGDIPPTFPTRT-------ELAS-PCD-NGRCINTHGGFECECELGYVLDATAQR 344
+ + R D T T E AS PC+ N C+ G F C C GY + +
Sbjct: 203 VNGF-RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGY----SGEL 257
Query: 345 C-LDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAK 403
C +D + G+C + L G GF
Sbjct: 258 CEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPG---AFSFRHAAGFLCHCPPGF-- 312
Query: 404 LDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
+GA C +VDECA S GG C + ++C CP G
Sbjct: 313 -EGADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDG 349
Score = 48.4 bits (110), Expect = 5e-05
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 8/63 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCR-NTAGSYTCLCE 66
+G C+++ F C C PG+ EG C VD C P C RGRC + G + C C
Sbjct: 1068 DGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCP 1121
Query: 67 PGF 69
PGF
Sbjct: 1122 PGF 1124
Score = 46.4 bits (105), Expect = 2e-04
Identities = 28/85 (32%), Positives = 31/85 (36%), Gaps = 6/85 (7%)
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
PG G C CA G C + +F C C G+ VD C
Sbjct: 1045 PGTPAPILG-CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEA---HVDPCHS 1100
Query: 127 QRVCRNGRCHNTP-GSFRCECLPGF 150
C GRCH P G F C C PGF
Sbjct: 1101 AP-CARGRCHTHPDGRFECRCPPGF 1124
Score = 44.4 bits (100), Expect = 8e-04
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 8/67 (11%)
Query: 205 PGACPH-GSCENLEPGYRCICDPGYH-PDADGLCRDIDECDMHQSYCAGGQCR-NTAGSF 261
P C H G+C +L + C C PG+ P + +D C H + CA G+C + G F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEA---HVDPC--HSAPCARGRCHTHPDGRF 1116
Query: 262 TCVCPEG 268
C CP G
Sbjct: 1117 ECRCPPG 1123
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRC- 94
CR C +P + G CR+ ++ C C PG+ A VD C + + C GRC
Sbjct: 1054 CRGAPVCAPSPCL-HDGACRDLFDAFACACGPGWEGPRCE--AHVDPCHS-APCARGRCH 1109
Query: 95 VNSEGSFQCVCEAGY 109
+ +G F+C C G+
Sbjct: 1110 THPDGRFECRCPPGF 1124
Score = 37.1 bits (82), Expect = 0.13
Identities = 19/35 (54%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCP 439
G TC DVDEC LS GGTC +T Y C CP
Sbjct: 352 GPTCEEDVDEC-LSDPCLHGGTCSDTVAGYICRCP 385
Score = 36.7 bits (81), Expect = 0.17
Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 4/68 (5%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C D C+ D GG C+ + F C C A + T C C Q C
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANF----TGPTCAQQLWCPGQPCLPPATCE 860
Query: 137 NTPGSFRC 144
P F C
Sbjct: 861 EVPDGFVC 868
Score = 31.5 bits (68), Expect = 6.3
Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 4/39 (10%)
Query: 405 DGATCR-DVDECALSAELCAGGTC-VNTDGSYRCDCPPG 441
+G C VD C + CA G C + DG + C CPPG
Sbjct: 1087 EGPRCEAHVDPCHSAP--CARGRCHTHPDGRFECRCPPG 1123
>AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein.
Length = 448
Score = 125 bits (301), Expect = 4e-28
Identities = 82/234 (35%), Positives = 111/234 (47%), Gaps = 18/234 (7%)
Query: 64 LCEPGFAPTAAGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDV 121
+C G+ + C DVDECA DS C + C+N +G + C C GY G C+D+
Sbjct: 112 ICRFGYQMDESNQCVDVDECATDSHQCNPTQICINMKGGYTCSCTDGY--WLLEGQCLDI 169
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSC-QAC-PAQGS 178
DEC C+ C N PGS+ C C PGFTL+ DGR+C + + C Q C GS
Sbjct: 170 DEC-RYGYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGS 227
Query: 179 ELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGY-HPDADG 234
+ C G + G +D++EC+ C H C N Y C C PGY D +
Sbjct: 228 --FICRCDPGYELEEDGVHCSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNR 284
Query: 235 LCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE 287
C+DI+EC+ C Q C N G F C+ P EP L++ + C E
Sbjct: 285 SCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRC-EEPYLRISDNRCMCPAE 337
Score = 122 bits (295), Expect = 2e-27
Identities = 63/150 (42%), Positives = 80/150 (53%), Gaps = 7/150 (4%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
IC N+ GG+ C C GY EG C D+DECR C++ C N GSY+C C PGF
Sbjct: 143 ICINMKGGYTCSCTDGYWL-LEGQ-CLDIDECRYG--YCQQ-LCANVPGSYSCTCNPGFT 197
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
G C DV+ECA ++ C CVN+ GSF C C+ GY C D+DEC
Sbjct: 198 LNEDGRSCQDVNECATENPCVQ-TCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEF 256
Query: 130 CRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
C N PG++ C C PG+ L +D R+C
Sbjct: 257 LCQHECVNQPGTYFCSCPPGYILLDDNRSC 286
Score = 120 bits (290), Expect = 8e-27
Identities = 88/295 (29%), Positives = 125/295 (42%), Gaps = 26/295 (8%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE--- 66
+C G + C G++ + C D+DECR P CR C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCHSRTNP 74
Query: 67 ----PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
P P + Y A + S +C GY+ + CVDVD
Sbjct: 75 VYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTI----SRPLICRFGYQMDESN-QCVDVD 129
Query: 123 ECE-EQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPAQGSE 179
EC + C + C N G + C C G+ L +G+ CL + + +G Q C A
Sbjct: 130 ECATDSHQCNPTQICINMKGGYTCSCTDGYWLL-EGQ-CLDIDECRYGYCQQLC-ANVPG 186
Query: 180 LYAVLCPEGPSKDNGGA---DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL- 235
Y+ C G + + G D+NEC A C +C N + C CDPGY + DG+
Sbjct: 187 SYSCTCNPGFTLNEDGRSCQDVNEC-ATENPCVQ-TCVNTYGSFICRCDPGYELEEDGVH 244
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETET 290
C D+DEC + C +C N G++ C CP G + + C+DI+ECE T
Sbjct: 245 CSDMDECSFSEFLCQH-ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHT 298
Score = 115 bits (277), Expect = 3e-25
Identities = 78/226 (34%), Positives = 100/226 (44%), Gaps = 16/226 (7%)
Query: 22 ICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADV 80
IC+ GY+ E C DVDEC + C + C N G YTC C G+ G C D+
Sbjct: 112 ICRFGYQM-DESNQCVDVDECATDSHQCNPTQICINMKGGYTCSCTDGYW-LLEGQCLDI 169
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPG 140
DEC C+ C N GS+ C C G+ +C DV+EC + C C NT G
Sbjct: 170 DECRY-GYCQ-QLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ-TCVNTYG 226
Query: 141 SFRCECLPGFTLSNDGRTCLGL-KLGWG-VSCQACPAQGSELYAVLCPEG--PSKDNGGA 196
SF C C PG+ L DG C + + + CQ Y CP G DN
Sbjct: 227 SFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSC 286
Query: 197 -DINECTAVPGACP-HGSCENLEPGYRCI----CDPGYHPDADGLC 236
DINEC C +C NL+ G++CI C+ Y +D C
Sbjct: 287 QDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRC 332
Score = 109 bits (263), Expect = 1e-23
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 8/144 (5%)
Query: 5 GMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECR-DNPRVCRRGRCRNTAGSYTC 63
G C +C N+ G + C C PG+ +G C+DV+EC +NP V C NT GS+ C
Sbjct: 175 GYCQQ-LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCV---QTCVNTYGSFIC 230
Query: 64 LCEPGFAPTAAG-YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+PG+ G +C+D+DEC+ CVN G++ C C GY +C D++
Sbjct: 231 RCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDIN 290
Query: 123 ECEEQ-RVCR-NGRCHNTPGSFRC 144
ECE + C C+N G F+C
Sbjct: 291 ECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 52.4 bits (120), Expect = 3e-06
Identities = 73/268 (27%), Positives = 98/268 (36%), Gaps = 50/268 (18%)
Query: 197 DINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
DI+EC +P AC C N GY +C +P G + Y A
Sbjct: 42 DIDECRTIPEACRGDMMCVNQNGGY--LCHSRTNPVYRGPYSNPYSTPYSGPYPAAAPPL 99
Query: 256 NTAG----SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
+ S +C G + + Q C D+DEC T++H PT+
Sbjct: 100 SAPNYPTISRPLICRFGYQMDESNQ-CVDVDECA--TDSHQCN------------PTQI- 143
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDN---RRGSCWRRV--VDGQCEAAA 366
CIN GG+ C C GY L +CLD R G C + V G
Sbjct: 144 ---------CINMKGGYTCSCTDGYWL--LEGQCLDIDECRYGYCQQLCANVPGSYSCTC 192
Query: 367 -PELLLRQE---C-----CCSVGLAWGSXXXXXXXXXXXXXKGFA-KLDGATCRDVDECA 416
P L ++ C C + + G+ + DG C D+DEC+
Sbjct: 193 NPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECS 252
Query: 417 LSAELCAGGTCVNTDGSYRCDCPPGLTL 444
S LC CVN G+Y C CPPG L
Sbjct: 253 FSEFLCQH-ECVNQPGTYFCSCPPGYIL 279
Score = 40.7 bits (91), Expect = 0.010
Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 400 GFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G+ L+G C D+DEC C C N GSY C C PG TL+ G
Sbjct: 158 GYWLLEGQ-CLDIDECRYG--YCQQ-LCANVPGSYSCTCNPGFTLNEDG 202
Score = 34.3 bits (75), Expect = 0.90
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 1/29 (3%)
Query: 409 CRDVDECALSAELCAGG-TCVNTDGSYRC 436
C D+DEC E C G CVN +G Y C
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein.
Length = 320
Score = 124 bits (299), Expect = 6e-28
Identities = 62/150 (41%), Positives = 78/150 (52%), Gaps = 7/150 (4%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+C N+ G F C C PGY+ G C D+DEC P C + RC NT GS+ C C PGF
Sbjct: 16 VCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQ 71
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
A Y C D++EC A + C +C N GSF C C GY ++ R C D+DEC
Sbjct: 72 LAANNYTCVDINECDASNQC-AQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSY 130
Query: 130 CRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
+C N PG F C C G+ + RTC
Sbjct: 131 LCQYQCVNEPGKFSCMCPQGYQVVR-SRTC 159
Score = 109 bits (261), Expect = 3e-23
Identities = 69/196 (35%), Positives = 92/196 (46%), Gaps = 22/196 (11%)
Query: 80 VDECAADSM-CKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN 137
+DEC A + C+ + C+N GSF C C GY+ + CVD+DEC C RC N
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ--CVDIDECTIPPYCHQ-RCVN 57
Query: 138 TPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL------CPEG--P 189
TPGSF C+C PGF L+ + TC+ + C A + Y +L C +G
Sbjct: 58 TPGSFYCQCSPGFQLAANNYTCVDIN-----ECDASNQCAQQCYNILGSFICQCNQGYEL 112
Query: 190 SKDN-GGADINECTAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRDIDECDMHQS 247
S D DI+EC C + C N EPG + C+C GY C+DI+EC+
Sbjct: 113 SSDRLNCEDIDECRTSSYLCQY-QCVN-EPGKFSCMCPQGYQVVRSRTCQDINECETTNE 170
Query: 248 YCAGGQCRNTAGSFTC 263
C N G F C
Sbjct: 171 CREDEMCWNYHGGFRC 186
Score = 85.4 bits (202), Expect = 4e-16
Identities = 61/176 (34%), Positives = 79/176 (44%), Gaps = 13/176 (7%)
Query: 121 VDECEE-QRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSC-QACPAQ 176
+DEC CR + C N GSF C+C PG+ G C+ + + C Q C
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGY--QKRGEQCVDIDECTIPPYCHQRCVNT 58
Query: 177 GSELYAVLCPEGPSKDNGGA--DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
Y P N DINEC A C C N+ + C C+ GY +D
Sbjct: 59 PGSFYCQCSPGFQLAANNYTCVDINECDA-SNQCAQ-QCYNILGSFICQCNQGYELSSDR 116
Query: 235 L-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETE 289
L C DIDEC SY QC N G F+C+CP+G + + C+DI+ECE E
Sbjct: 117 LNCEDIDECRT-SSYLCQYQCVNEPGKFSCMCPQGYQ-VVRSRTCQDINECETTNE 170
Score = 80.2 bits (189), Expect = 1e-14
Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G F C C GYE S+ C D+DECR + +C+ +C N G ++C+C G+
Sbjct: 95 CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQV 153
Query: 72 TAAGYCADVDECAADSMCKGGR-CVNSEGSFQC 103
+ C D++EC + C+ C N G F+C
Sbjct: 154 VRSRTCQDINECETTNECREDEMCWNYHGGFRC 186
Score = 66.5 bits (155), Expect = 2e-10
Identities = 63/204 (30%), Positives = 73/204 (35%), Gaps = 55/204 (26%)
Query: 239 IDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDY 297
IDEC C Q C N GSF C CP G + E C DIDEC
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ--CVDIDECT------------ 46
Query: 298 ERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRV 357
IPP C RC+NT G F C+C G+ L A C+D
Sbjct: 47 ----IPPY----------CHQ-RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDA---- 87
Query: 358 VDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECAL 417
QC +L C C+ G S D C D+DEC
Sbjct: 88 -SNQCAQQCYNILGSFICQCNQGYELSS-------------------DRLNCEDIDECRT 127
Query: 418 SAELCAGGTCVNTDGSYRCDCPPG 441
S+ LC CVN G + C CP G
Sbjct: 128 SSYLCQ-YQCVNEPGKFSCMCPQG 150
Score = 39.1 bits (87), Expect = 0.032
Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
G C D+DEC + C CVNT GS+ C C PG L
Sbjct: 36 GEQCVDIDECTIPP-YCHQ-RCVNTPGSFYCQCSPGFQL 72
Score = 33.1 bits (72), Expect = 2.1
Identities = 34/126 (26%), Positives = 45/126 (35%), Gaps = 28/126 (22%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
CIN G F C+C GY ++C+D C + C C CS G
Sbjct: 17 CINLRGSFACQCPPGY--QKRGEQCVDI--DEC---TIPPYCHQRCVNTPGSFYCQCSPG 69
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPP 440
+ + TC D++EC S + CA C N GS+ C C
Sbjct: 70 FQLAA-------------------NNYTCVDINECDASNQ-CAQ-QCYNILGSFICQCNQ 108
Query: 441 GLTLDS 446
G L S
Sbjct: 109 GYELSS 114
>AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.
Length = 1200
Score = 124 bits (298), Expect = 9e-28
Identities = 136/463 (29%), Positives = 182/463 (39%), Gaps = 73/463 (15%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGSYTCLCEP 67
G C + GFECIC + GA C+ DV++CR C+ G C++ Y C+C
Sbjct: 398 GTCVDQVDGFECICPEQWV----GATCQLDVNDCRGQ---CQHGGTCKDLVNGYQCVCPR 450
Query: 68 GFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
GF +C + D+CA+ GG C + F C C G+ VDVD CE
Sbjct: 451 GFG---GRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---VDVDLCEP 504
Query: 127 QRVCRNG-RCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLC 185
CRNG RC+N G + C C F G+ C V + CP +
Sbjct: 505 SP-CRNGARCYNLEGDYYCACPDDF----GGKNC-------SVPREPCPGGACRVI---- 548
Query: 186 PEGPSKDNGGADINECTAVPGAC-PHGSCENLEPG--YRCICDPGYHPDADGLCRD-IDE 241
+G D G TA G C PHG C + +PG + CICD G+ C + ID+
Sbjct: 549 -DGCGSDAGPGMPG--TAASGVCGPHGRCVS-QPGGNFSCICDSGF---TGTYCHENIDD 601
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDI--DECEGETETHYIESDY-- 297
C + Q GG C + +F C CP G E D D C + + +D+
Sbjct: 602 C-LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYC 660
Query: 298 --ERGDIPPTFPTRTEL--ASPCDNG-RCINTHGGFECECELGYVLDATA----QRCLDN 348
+ G T +R A C NG C ++ F C C G+ A CL N
Sbjct: 661 ACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPN 720
Query: 349 ---RRGSCWRRVVDGQC---EAAAPELLLRQECCCSVGLAW--GSXXXXXXXXXXXXXKG 400
G+C C + C+ + G G
Sbjct: 721 PCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPG 780
Query: 401 FAKLDGATCR-DVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
FA G CR ++DEC S CA G TCV+ YRC CPPG
Sbjct: 781 FA---GPDCRINIDECQSSP--CAYGATCVDEINGYRCSCPPG 818
Score = 105 bits (252), Expect = 3e-22
Identities = 119/458 (25%), Positives = 170/458 (37%), Gaps = 55/458 (12%)
Query: 7 CTNG-ICKNIDGG-FECICKPGYESGSEGALCRDVDE-CRDNPRVCRRGRCRNTAGSYTC 63
CTNG C N + + C C GY G C + C NP G C + C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYS----GRNCEKAEHACTSNP-CANGGSCHEVPSGFEC 371
Query: 64 LCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C G++ PT A D+DECA++ GG CV+ F+C+C + + +DV+
Sbjct: 372 HCPSGWSGPTCA---LDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQ---LDVN 425
Query: 123 ECEEQRVCRN-GRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+C Q C++ G C + ++C C GF + C G C+ A G
Sbjct: 426 DCRGQ--CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDL-ADGF 482
Query: 179 ELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCR 237
+ CP+G S D++ C P C +G+ C NLE Y C C PD G
Sbjct: 483 HCH---CPQGFSGPLCEVDVDLCE--PSPCRNGARCYNLEGDYYCAC-----PDDFG--- 529
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDY 297
C + + C GG CR G + P G +C C + ++
Sbjct: 530 -GKNCSVPREPCPGGACRVIDGCGSDAGP-GMPGTAASGVCGPHGRCVSQPGGNF-SCIC 586
Query: 298 ERGDIPPTFPTRTE--LASPCDN-GRCINTHGGFECECELGY---VLDATAQRCLD---N 348
+ G + L PC N G CI+ F C C G+ + D CL +
Sbjct: 587 DSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCH 646
Query: 349 RRGSCWRRVVDGQCEA----AAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL 404
RG C+ V D C R+ C + + G K
Sbjct: 647 SRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK- 705
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
G+TC + C GGTCV + S+ C C G
Sbjct: 706 -GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDG 742
Score = 102 bits (244), Expect = 3e-21
Identities = 122/436 (27%), Positives = 168/436 (38%), Gaps = 62/436 (14%)
Query: 41 ECRDNPRVCRRGRCRNTAGSYT----CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVN 96
EC++ VC++G C G T C C G+ +C DEC C G CV
Sbjct: 239 ECKE--AVCKQG-CNLLHGGCTVPGECRCSYGWQ---GRFC---DECVPYPGCVHGSCVE 289
Query: 97 SEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNG-RCHNT-PGSFRCECLPGFTLSN 154
+QC CE + D++ C C NG C N P +RC C G++ N
Sbjct: 290 P---WQCNCETNWGGLLCDK---DLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRN 343
Query: 155 DGRT---CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG 211
+ C G SC P+ G E + CP G S DI+EC + P A G
Sbjct: 344 CEKAEHACTSNPCANGGSCHEVPS-GFECH---CPSGWSGPTCALDIDECASNPCAAG-G 398
Query: 212 SCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGT 269
+C + G+ CIC + C+ D+++C + C GG C++ + CVCP G
Sbjct: 399 TCVDQVDGFECICPEQW---VGATCQLDVNDC---RGQCQHGGTCKDLVNGYQCVCPRGF 452
Query: 270 --RH-EPELQLCRDIDECEG---ETETHYIESDYERGDIPPTFPTRTELA--SPCDNG-R 320
RH E E C G E +G P +L SPC NG R
Sbjct: 453 GGRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGAR 512
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRR----GSCWRRVVDGQCEAAAPELLLRQECC 376
C N G + C C D + C R G+C RV+DG C + A +
Sbjct: 513 CYNLEGDYYCACPD----DFGGKNCSVPREPCPGGAC--RVIDG-CGSDAGPGMPGTAAS 565
Query: 377 CSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYR 435
G GF G C + +D+C L GGTC++ ++R
Sbjct: 566 GVCGPHGRCVSQPGGNFSCICDSGFT---GTYCHENIDDC-LGQPCRNGGTCIDEVDAFR 621
Query: 436 CDCPPGLTLDSTGTAP 451
C CP G + T P
Sbjct: 622 CFCPSGWEGELCDTNP 637
Score = 100 bits (240), Expect = 9e-21
Identities = 106/392 (27%), Positives = 163/392 (41%), Gaps = 70/392 (17%)
Query: 5 GMC-TNGICKNIDGG-FECICKPGYESGSEGALCRD-VDECRDNPRVCRRG-RCRNTAGS 60
G+C +G C + GG F CIC +SG G C + +D+C P CR G C + +
Sbjct: 566 GVCGPHGRCVSQPGGNFSCIC----DSGFTGTYCHENIDDCLGQP--CRNGGTCIDEVDA 619
Query: 61 YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD 120
+ C C G+ + ++C D GRC + F C C+ G++
Sbjct: 620 FRCFCPSGWEGELCD--TNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR--- 674
Query: 121 VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW-----GVSCQACPA 175
+C+ G C+++ +FRC C PG+ G TC K V+ C
Sbjct: 675 EFQCDAYTCSNGGTCYDSGDTFRCACPPGW----KGSTCAVAKNSSCLPNPCVNGGTCVG 730
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGY-HPDAD 233
G+ ++ +C +G + N+C +P C +G C + +RC C PG+ PD
Sbjct: 731 SGAS-FSCICRDGWEGRTCTHNTNDCNPLP--CYNGGICVDGVNWFRCECAPGFAGPD-- 785
Query: 234 GLCR-DIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
CR +IDEC S CA G C + + C CP G R P C+++
Sbjct: 786 --CRINIDEC--QSSPCAYGATCVDEINGYRCSCPPG-RAGPR---CQEV--------IG 829
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE--------CELGYVLDATA- 342
+ S + RG FP + C++ RC++ G +C C L +A +
Sbjct: 830 FGRSCWSRG---TPFPHGSSWVEDCNSCRCLD--GRRDCSKVWCGWKPCLLAGQPEALSA 884
Query: 343 -----QRCLDNRRGSCWRRVVD--GQCEAAAP 367
QRCL+ G C R + G+C A P
Sbjct: 885 QCPLGQRCLEKAPGQCLRPPCEAWGECGAEEP 916
>AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens
cDNA FLJ16811 fis, clone THYMU3024602, highly similar
to Cell surface glycoprotein EMR1 precursor. ).
Length = 867
Score = 123 bits (297), Expect = 1e-27
Identities = 84/255 (32%), Positives = 111/255 (43%), Gaps = 54/255 (21%)
Query: 40 DECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY--------CADVDECAADSMC-K 90
+ CRD+ C NT SY C C+ GF + C D++EC S+C +
Sbjct: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINECLTSSVCPE 92
Query: 91 GGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC-RNGRCHNTPGSFRCECLPG 149
CVNS GS+ C C+ G+ + C DVDEC + R C + C+NT G++ C C PG
Sbjct: 93 HSDCVNSMGSYSCSCQVGF--ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPG 150
Query: 150 FTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACP 209
F S+ + GLK SC+ DI+ECT + CP
Sbjct: 151 FESSSGHLSFQGLK----ASCE-------------------------DIDECTEM---CP 178
Query: 210 -HGSCENLEPGYRCICDPGYHPDADGL--------CRDIDECDMHQSYCAGGQ-CRNTAG 259
+ +C N Y C C PG+ P L CRDIDEC S C C N G
Sbjct: 179 INSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALG 238
Query: 260 SFTCVCPEGTRHEPE 274
S++C C G PE
Sbjct: 239 SYSCGCIAGFHPNPE 253
Score = 105 bits (251), Expect = 4e-22
Identities = 59/164 (35%), Positives = 80/164 (48%), Gaps = 24/164 (14%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCRNTAGSYTCLCEPGFA 70
C N G + C C+ G+ S + C DVDEC D PR C C NT G+Y+C C PGF
Sbjct: 96 CVNSMGSYSCSCQVGFIS--RNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFCNPGFE 152
Query: 71 PTAA--------GYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPT------ATR 115
++ C D+DEC MC C N+ GS+ C C G+ P+ +
Sbjct: 153 SSSGHLSFQGLKASCEDIDECT--EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQ 210
Query: 116 GA-CVDVDEC-EEQRVC-RNGRCHNTPGSFRCECLPGFTLSNDG 156
G C D+DEC ++ C N C N GS+ C C+ GF + +G
Sbjct: 211 GVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 254
Score = 77.8 bits (183), Expect = 7e-14
Identities = 67/214 (31%), Positives = 93/214 (43%), Gaps = 35/214 (16%)
Query: 106 EAGYRPTATRGACVDVDECEEQRVC-RNGRCHNTPGSFRCECLPGFTLSNDGRTCL---G 161
E RPT R + C + +C C NT S+ C C GF LS++G+ G
Sbjct: 19 EGHIRPT--RKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGF-LSSNGQNHFKDPG 75
Query: 162 LK---LGWGVSCQACPAQGSEL-----YAVLCPEG-PSKDNGGADINECTAVPGACP-HG 211
++ + ++ CP + Y+ C G S+++ D++EC A P ACP H
Sbjct: 76 VRCKDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDEC-ADPRACPEHA 134
Query: 212 SCENLEPGYRCICDPGY-----HPDADGL---CRDIDECDMHQSYCAGGQCRNTAGSFTC 263
+C N Y C C+PG+ H GL C DIDEC + C NT GS+ C
Sbjct: 135 TCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT--EMCPINSTCTNTPGSYFC 192
Query: 264 VCPEG-TRHEPELQL------CRDIDECEGETET 290
C G +L CRDIDEC + T
Sbjct: 193 TCHPGFAPSNGQLNFTDQGVECRDIDECRQDPST 226
Score = 63.7 bits (148), Expect = 1e-09
Identities = 31/79 (39%), Positives = 38/79 (48%), Gaps = 9/79 (11%)
Query: 6 MCT-NGICKNIDGGFECICKPGYESGS-------EGALCRDVDECRDNPRVC-RRGRCRN 56
MC N C N G + C C PG+ + +G CRD+DECR +P C C N
Sbjct: 176 MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTN 235
Query: 57 TAGSYTCLCEPGFAPTAAG 75
GSY+C C GF P G
Sbjct: 236 ALGSYSCGCIAGFHPNPEG 254
Score = 57.2 bits (132), Expect = 1e-07
Identities = 63/253 (24%), Positives = 90/253 (35%), Gaps = 49/253 (19%)
Query: 208 CP-HGSCENLEPGYRCICDPGY-------HPDADGL-CRDIDECDMHQSYCAG-GQCRNT 257
CP + +C N Y C C G+ H G+ C+DI+EC + S C C N+
Sbjct: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINEC-LTSSVCPEHSDCVNS 99
Query: 258 AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCD 317
GS++C C G C D+DEC P P +
Sbjct: 100 MGSYSCSCQVGFISRNST--CEDVDECAD----------------PRACP---------E 132
Query: 318 NGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCC 377
+ C NT G + C C G+ ++ + SC +D +C P + C
Sbjct: 133 HATCNNTVGNYSCFCNPGFE-SSSGHLSFQGLKASC--EDID-ECTEMCP---INSTCTN 185
Query: 378 SVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDGSYRC 436
+ G + + F G CRD+DEC C C N GSY C
Sbjct: 186 TPGSYFCTCHPGFAPSNGQL--NFTD-QGVECRDIDECRQDPSTCGPNSICTNALGSYSC 242
Query: 437 DCPPGLTLDSTGT 449
C G + G+
Sbjct: 243 GCIAGFHPNPEGS 255
Score = 48.0 bits (109), Expect = 7e-05
Identities = 55/218 (25%), Positives = 80/218 (36%), Gaps = 46/218 (21%)
Query: 226 PGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
P P+ G CRD C + + C NT S+ C C +G
Sbjct: 24 PTRKPNTKGNNCRDSTLCPAYAT------CTNTVDSYYCACKQGF--------------L 63
Query: 285 EGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQR 344
+ H+ + DI T P ++ C+N+ G + C C++G++
Sbjct: 64 SSNGQNHFKDPGVRCKDINECL---TSSVCP-EHSDCVNSMGSYSCSCQVGFI------- 112
Query: 345 CLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKL 404
+R +C VD E A P + C+ + S F L
Sbjct: 113 ---SRNSTC--EDVD---ECADPRAC-PEHATCNNTVGNYSCFCNPGFESSSGHLSFQGL 163
Query: 405 DGATCRDVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
A+C D+DEC E+C TC NT GSY C C PG
Sbjct: 164 K-ASCEDIDECT---EMCPINSTCTNTPGSYFCTCHPG 197
>AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein.
Length = 502
Score = 119 bits (287), Expect = 2e-26
Identities = 92/278 (33%), Positives = 121/278 (43%), Gaps = 32/278 (11%)
Query: 2 TNGGMCTNGICKNIDGGFE-CICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTA 58
+NGG C + D F C+C PG+ G C + D C + C+ G C++
Sbjct: 243 SNGGTCQ--LMPEKDSTFHLCLCPPGFI----GPGCEVNPDNCVSHQ--CQNGGTCQDGL 294
Query: 59 GSYTCLCEPGFAPTAAGYCADVDECAADSM--CK-GGRCVNSEGSFQCVCEAGYRPTATR 115
+YTCLC + T DVDEC A C+ GG C NS GSF CVC +G+ T+
Sbjct: 295 DTYTCLCPETW--TGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE 352
Query: 116 GACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT--LSNDGRTCLGLKLGWGVSCQAC 173
++D+C C + GSF C C PG T L + CL C
Sbjct: 353 E---NLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTN 409
Query: 174 PAQGSELYAVLCPEGPSKDNGGADINECTAV---PGACPHG-SCENLEPGYRCICDPGYH 229
P GS L LC G S D++EC P C HG SC N + C+C PGY
Sbjct: 410 PLTGSTL--CLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY- 466
Query: 230 PDADGLCR-DIDECDMHQSYCAGGQCRNTAGSFTCVCP 266
C D +EC + Q G C + +F C+CP
Sbjct: 467 --TGSRCEADHNEC-LSQPCHPGSTCLDLLATFHCLCP 501
Score = 116 bits (278), Expect = 2e-25
Identities = 125/438 (28%), Positives = 173/438 (39%), Gaps = 51/438 (11%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCR-NTAGSYTCLCEPGFAPTAAGY 76
F C C PG+ E + D C P C +RGRC +G C C PG+
Sbjct: 100 FLCTCLPGFTG--ERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT---GEQ 152
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNG-R 134
C D C+A+ GG C+ + QC C G+ A DV+EC ++ C G
Sbjct: 153 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS 209
Query: 135 CHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSK 191
CHNT GSF+C C G C G +CQ P + S + LCP P
Sbjct: 210 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP--PGF 267
Query: 192 DNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH-QSYC 249
G ++N V C + G+C++ Y C+C P D D+DEC+ +C
Sbjct: 268 IGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC-PETWTGWD-CSEDVDECEAQGPPHC 325
Query: 250 A-GGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPT 305
GG C+N+AGSF CVC GT E L C G T I+ + P
Sbjct: 326 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGST---CIDRVGSFSCLCP- 381
Query: 306 FPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA 365
P RT L ++ C++ + +C + +T C G C
Sbjct: 382 -PGRTGLLCHLED-MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP--------TCHQD 431
Query: 366 APELLLRQE--CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELC 422
E L+ Q+ C G GS G+ G+ C D +EC LS
Sbjct: 432 LDECLMAQQGPSPCEHG---GSCLNTPGSFNCLCPPGYT---GSRCEADHNEC-LSQPCH 484
Query: 423 AGGTCVNTDGSYRCDCPP 440
G TC++ ++ C CPP
Sbjct: 485 PGSTCLDLLATFHCLCPP 502
Score = 107 bits (256), Expect = 1e-22
Identities = 97/287 (33%), Positives = 126/287 (43%), Gaps = 46/287 (16%)
Query: 5 GMCTNGI-CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCR----NT 57
G C G C N G F+C+C G EG C C PR C G C+
Sbjct: 202 GPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCP--PRGCSNGGTCQLMPEKD 255
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
+ + CLC PGF G + D C + GG C + ++ C+C T T
Sbjct: 256 STFHLCLCPPGFI--GPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPE----TWTGWD 309
Query: 118 CV-DVDECEEQRV--CRNG-RCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSC 170
C DVDECE Q CRNG C N+ GSF C C+ G+ + + C+ G +C
Sbjct: 310 CSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 369
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG----SCENLEPGYRCICDP 226
GS ++ LCP G + + + C + P C HG S L C+C P
Sbjct: 370 --IDRVGS--FSCLCPPGRTGLLCHLE-DMCLSQP--C-HGDAQCSTNPLTGSTLCLCQP 421
Query: 227 GYHPDADGLC-RDIDECDMHQ---SYCA-GGQCRNTAGSFTCVCPEG 268
GY + C +D+DEC M Q S C GG C NT GSF C+CP G
Sbjct: 422 GY---SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPG 465
Score = 90.6 bits (215), Expect = 1e-17
Identities = 127/462 (27%), Positives = 170/462 (36%), Gaps = 81/462 (17%)
Query: 42 CRDNPRVCRRG-RCRNTA-GSYTCLCEPGFAPTAAGYCADVDECAADSMCK-GGRCV--- 95
C P C G C + + G TC C PGF C D C +C+ GG C
Sbjct: 27 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQALL 83
Query: 96 -------NSEG----SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH-NTPGSFR 143
+S SF C C G+ T R D C + GRCH G +
Sbjct: 84 PAPLGLPSSPSPLTPSFLCTCLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 141
Query: 144 CECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--YAVL---CPEGPSKDNGGADI 198
C C+PG+T G C +L S C G L Y + CP G D+
Sbjct: 142 CSCMPGWT----GEQC---QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 194
Query: 199 NECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCR- 255
NEC PG CP G SC N ++C+C G +G ++ C+ GG C+
Sbjct: 195 NECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQL 250
Query: 256 ---NTAGSFTCVCP-----EGTRHEPE---LQLCRDIDECEG--ETETHYIESDYERGDI 302
+ C+CP G P+ C++ C+ +T T + D
Sbjct: 251 MPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 310
Query: 303 PPTFPTRTELASP-CDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGS 352
P C N G C N+ G F C C G+ + D A C +
Sbjct: 311 SEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG--ST 368
Query: 353 CWRRV--VDGQCEAAAPELLLRQECCC----SVGLAWGSXXXXXXXXXXXXXKGFAKLDG 406
C RV C LL E C G A S G++ G
Sbjct: 369 CIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS---G 425
Query: 407 ATC-RDVDECALSAE---LCA-GGTCVNTDGSYRCDCPPGLT 443
TC +D+DEC ++ + C GG+C+NT GS+ C CPPG T
Sbjct: 426 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 467
Score = 88.6 bits (210), Expect = 4e-17
Identities = 94/352 (26%), Positives = 134/352 (38%), Gaps = 57/352 (16%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGSYTC 63
C NG +C +C C PG+ EG C RDV+EC +P C +G C NT GS+ C
Sbjct: 164 CVNGGVCLATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 219
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRC---VNSEGSFQ-CVCEAGYRPTATRGACV 119
LC G A C GG C + +F C+C G+ G V
Sbjct: 220 LCPVGQEGPRCELRA--GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF---IGPGCEV 274
Query: 120 DVDECEEQRVCRNGRCHNTPGSFRCEC---LPGFTLSNDGRTCLGLKLGWGVSCQACPAQ 176
+ D C + G C + ++ C C G+ S D C + C
Sbjct: 275 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNS 334
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLC 236
+ V C G + ++++C A A P +C + + C+C PG GL
Sbjct: 335 AGSFHCV-CVSGWGGTSCEENLDDCIAATCA-PGSTCIDRVGSFSCLCPPG----RTGLL 388
Query: 237 RDIDECDMHQSYCAGGQCRNT--AGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
+++ + Q QC GS C+C G P +D+DEC
Sbjct: 389 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPG-YSGPTCH--QDLDEC---------- 435
Query: 295 SDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGYVLDATAQRC 345
++G SPC++ G C+NT G F C C GY T RC
Sbjct: 436 LMAQQG------------PSPCEHGGSCLNTPGSFNCLCPPGY----TGSRC 471
>AK074499-1|BAC11024.1| 636|Homo sapiens protein ( Homo sapiens
cDNA FLJ90018 fis, clone HEMBA1000732, highly similar to
Homo sapiens mRNA for latent transforming growth
factor-beta ).
Length = 636
Score = 118 bits (285), Expect = 3e-26
Identities = 52/104 (50%), Positives = 65/104 (62%), Gaps = 4/104 (3%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRD-NPRVCRRGRCRNTAGSYTCL 64
+C +GIC N DG FECIC PG+ +G + A C DVDECR+ P +CR RC N+ GSY C+
Sbjct: 27 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRCENSPGSYRCV 86
Query: 65 --CEPGFAPTAAGYCADVDEC-AADSMCKGGRCVNSEGSFQCVC 105
C+PG+ G C DV+EC +C C N EGSF CVC
Sbjct: 87 RDCDPGYHAGPEGTCDDVNECETLQGVCGAALCENVEGSFLCVC 130
Score = 107 bits (257), Expect = 8e-23
Identities = 90/301 (29%), Positives = 132/301 (43%), Gaps = 38/301 (12%)
Query: 78 ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ--RVCRNGRC 135
ADVDEC+ + +C+ G C N++GSF+C+C G+R +C+DVDEC E+ +CR+ RC
Sbjct: 17 ADVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRC 76
Query: 136 HNTPGSFRC--ECLPGFTLSNDGRTCLGL---KLGWGVSCQACPAQGSE-LYAVLCPEGP 189
N+PGS+RC +C PG+ +G TC + + GV C A + E + +CP P
Sbjct: 77 ENSPGSYRCVRDCDPGYHAGPEG-TCDDVNECETLQGV-CGAALCENVEGSFLCVCPNSP 134
Query: 190 SKDN--GGADINECTAV---PGACPHGSCENLEPGY-------RCICDPGYHPDADGLCR 237
+ + G + T+ PG+ P + P R P P G R
Sbjct: 135 EEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGR-R 193
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG-ETETHYIESD 296
+ C RN C C G E CR I +C G ET +
Sbjct: 194 ECYFDTAAPDACDNILARNVTWQ-ECCCTVG---EGWGSGCR-IQQCPGTETAEYQSLCP 248
Query: 297 YERGDIPPT--FPTRTEL-------ASPCDNGRCINTHGGFECECELGYVLDATAQRCLD 347
+ RG + P+ R ++ C +G C+NT G+ C C GY C+D
Sbjct: 249 HGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECID 308
Query: 348 N 348
N
Sbjct: 309 N 309
Score = 96.7 bits (230), Expect = 1e-19
Identities = 87/283 (30%), Positives = 117/283 (41%), Gaps = 40/283 (14%)
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD-GLCRDIDEC-DMHQSYCAGGQ 253
AD++EC+ C G C N + + CIC PG+ D C D+DEC + + C +
Sbjct: 17 ADVDECSE-EDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQR 75
Query: 254 CRNTAGSFTCV--CPEGTRHEPELQLCRDIDECEG-ETETHYIESDYERGDIPPTFPTRT 310
C N+ GS+ CV C G PE C D++ECE + + G P
Sbjct: 76 CENSPGSYRCVRDCDPGYHAGPE-GTCDDVNECETLQGVCGAALCENVEGSFLCVCPNSP 134
Query: 311 ELASPCDNGRCI------NTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDG---- 360
E P GRC+ T G + + VL A RR S R+ G
Sbjct: 135 EEFDPM-TGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRR 193
Query: 361 QC--EAAAPE----LLLR----QECCCSVGLAWGS---------XXXXXXXXXXXXXKGF 401
+C + AAP+ +L R QECCC+VG WGS +G+
Sbjct: 194 ECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGY 253
Query: 402 AKLDG--ATCRDVDECALSAE-LCAGGTCVNTDGSYRCDCPPG 441
G + RDVDEC L + +C G CVNT Y C C G
Sbjct: 254 LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNG 296
Score = 86.6 bits (205), Expect = 2e-16
Identities = 47/120 (39%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Query: 49 CRRGRCRNT-AGSYTCLCEPG---FAPTA-AGYCADVDECAA--DSMCKGGRCVNSEGSF 101
CR +C T Y LC G AP+ DVDEC D +CK G CVN+ +
Sbjct: 230 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 289
Query: 102 QCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
C C GY R C+D DEC +E+ C GRC NT GS+ C C P L R C+
Sbjct: 290 SCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 349
Score = 86.6 bits (205), Expect = 2e-16
Identities = 57/156 (36%), Positives = 74/156 (47%), Gaps = 8/156 (5%)
Query: 34 ALCRDVDECR-DNPRVCRRGRCRNTAGSYTCLCEPG-FAPTAAGYCADVDECA-ADSMCK 90
+L RDVDEC+ +VC+ G C NTA Y+C C G + T C D DECA + C+
Sbjct: 261 SLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACE 320
Query: 91 GGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN-GRCHNTPGSFRCECLPG 149
GGRCVN+ GS+ C CE ++ CV E Q + N G C G+ P
Sbjct: 321 GGRCVNTVGSYHCTCEPPLVLDGSQRRCV---SNESQSLDDNLGVCWQEVGADLVCSHPR 377
Query: 150 FTLSNDGRTCLGL-KLGWGVSCQACPAQGSELYAVL 184
C L WG+ C CPAQ S+ + L
Sbjct: 378 LDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEAL 413
Score = 83.4 bits (197), Expect = 1e-15
Identities = 46/117 (39%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 159 CLGLKLGWGVSC--QACPAQGSELYAVLCPEG-----PSKDNG-GADINECTAVPG-ACP 209
C + GWG C Q CP + Y LCP G PS D D++EC C
Sbjct: 219 CCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCK 278
Query: 210 HGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
G C N PGY C C GY+ L C D DEC + C GG+C NT GS+ C C
Sbjct: 279 SGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 335
Score = 82.6 bits (195), Expect = 3e-15
Identities = 47/117 (40%), Positives = 58/117 (49%), Gaps = 10/117 (8%)
Query: 53 RCRNTAGSYTCLCEPGFAPTAAGYCAD------VDECAADSMCKGGRCVNSEGSFQCVCE 106
R R+T S+ EP + AG A+ +EC C GRCV F C C
Sbjct: 513 RSRDTRRSFPESEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCF 572
Query: 107 AGYRPTATRGACVDVDECEEQR----VCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
GYR TR ACVD++EC+E +C N RC NT GSFRC C PGF ++ C
Sbjct: 573 DGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 629
Score = 81.8 bits (193), Expect = 5e-15
Identities = 63/202 (31%), Positives = 79/202 (39%), Gaps = 43/202 (21%)
Query: 201 CTAVPG---ACPHGSCENLEPG-YRCICDPG---YHPDAD-GLCRDIDECDMHQSY-CAG 251
CT G C C E Y+ +C G P D L RD+DEC + + C
Sbjct: 220 CTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKS 279
Query: 252 GQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTE 311
G C NTA ++C C G + + C D DEC E
Sbjct: 280 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPA--------------------- 318
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRC-------LDNRRGSCWRRV-VDGQC- 362
C+ GRC+NT G + C CE VLD + +RC LD+ G CW+ V D C
Sbjct: 319 ----CEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCS 374
Query: 363 EAAAPELLLRQECCCSVGLAWG 384
ECCC G AWG
Sbjct: 375 HPRLDRQATYTECCCLYGEAWG 396
Score = 72.5 bits (170), Expect = 3e-12
Identities = 45/128 (35%), Positives = 56/128 (43%), Gaps = 12/128 (9%)
Query: 107 AGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL------ 160
AG P DVDEC E+ +C++G C NT GSF C C PG D +CL
Sbjct: 5 AGGGPGLRTPCPADVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECR 64
Query: 161 --GLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA--DINECTAVPGACPHGSCENL 216
G L C+ P GS C G G D+NEC + G C CEN+
Sbjct: 65 ERGPALCRSQRCENSP--GSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVCGAALCENV 122
Query: 217 EPGYRCIC 224
E + C+C
Sbjct: 123 EGSFLCVC 130
Score = 70.5 bits (165), Expect = 1e-11
Identities = 28/62 (45%), Positives = 34/62 (54%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
+C +G+C N G+ C C GY ++ C D DEC D C GRC NT GSY C C
Sbjct: 276 VCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 335
Query: 66 EP 67
EP
Sbjct: 336 EP 337
Score = 69.3 bits (162), Expect = 3e-11
Identities = 30/69 (43%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPR---VCRRGRCRNTAGSYTC 63
CTNG C + GF C C GY C D++EC + +C RC NT GS+ C
Sbjct: 555 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 614
Query: 64 LCEPGFAPT 72
+C PGFAPT
Sbjct: 615 ICRPGFAPT 623
Score = 58.8 bits (136), Expect = 4e-08
Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 7/83 (8%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQS---YCAGG 252
+ EC + G C +G C + G+ C C GY D + C DI+ECD ++ C
Sbjct: 545 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 603
Query: 253 QCRNTAGSFTCVCPEG--TRHEP 273
+C NT GSF C+C G H+P
Sbjct: 604 RCLNTDGSFRCICRPGFAPTHQP 626
Score = 52.0 bits (119), Expect = 4e-06
Identities = 22/39 (56%), Positives = 23/39 (58%)
Query: 409 CRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
C D DECA C GG CVNT GSY C C P L LD +
Sbjct: 306 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGS 344
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/113 (29%), Positives = 43/113 (38%), Gaps = 25/113 (22%)
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDY 297
+ +EC + C G+C FTC C +G R + C DI+EC+
Sbjct: 545 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECD------------ 591
Query: 298 ERGDIPPTFPTRTELASP-CDNGRCINTHGGFECECELGYVLDATAQRCLDNR 349
E ASP C N RC+NT G F C C G+ C R
Sbjct: 592 -----------EAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 633
Score = 44.0 bits (99), Expect = 0.001
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 405 DGATCRDVDECA-LSAELCAGGTCVNTDGSYRC--DCPPGLTLDSTGT 449
D A+C DVDEC LC C N+ GSYRC DC PG GT
Sbjct: 53 DLASCLDVDECRERGPALCRSQRCENSPGSYRCVRDCDPGYHAGPEGT 100
Score = 43.2 bits (97), Expect = 0.002
Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 3/36 (8%)
Query: 409 CRDVDEC---ALSAELCAGGTCVNTDGSYRCDCPPG 441
C D++EC ++ LC C+NTDGS+RC C PG
Sbjct: 584 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 619
Score = 37.9 bits (84), Expect = 0.073
Identities = 12/22 (54%), Positives = 15/22 (68%)
Query: 6 MCTNGICKNIDGGFECICKPGY 27
+C N C N DG F CIC+PG+
Sbjct: 599 LCVNARCLNTDGSFRCICRPGF 620
Score = 37.1 bits (82), Expect = 0.13
Identities = 14/44 (31%), Positives = 20/44 (45%)
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL 162
++ +EC C NGRC P F C C G+ L C+ +
Sbjct: 544 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDI 587
Score = 31.1 bits (67), Expect = 8.4
Identities = 12/30 (40%), Positives = 14/30 (46%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDP 226
D +EC AC G C N Y C C+P
Sbjct: 308 DNDECADEEPACEGGRCVNTVGSYHCTCEP 337
>D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein.
Length = 810
Score = 118 bits (284), Expect = 4e-26
Identities = 81/250 (32%), Positives = 108/250 (43%), Gaps = 26/250 (10%)
Query: 35 LCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA--AGYCADVDECAAD-SMCKG 91
+CR + C + P+ C+N TC C+ G+ + YC D+DECAA C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 92 GR-CVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVC-RNGRCHNTPGSFRCECLP 148
CVN G ++C C GY +C + DEC Q C N C NT C C P
Sbjct: 448 NTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 149 GFTLSNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVP 205
G+ +G C +G +C A P + +CP G + + DI+EC+
Sbjct: 507 GYV--GNGTICRAFCEEGCRYGGTCVA-PNK------CVCPSGFTGSHCEKDIDECSEGI 557
Query: 206 GAC-PHGSCENLEPGYRCICDPGYHPD-----ADGLCRDIDECDMHQSYC-AGGQCRNTA 258
C H C NL Y C C G+H D + C DIDEC + C C N A
Sbjct: 558 IECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLA 617
Query: 259 GSFTCVCPEG 268
G F C+CP G
Sbjct: 618 GGFDCLCPSG 627
Score = 81.8 bits (193), Expect = 5e-15
Identities = 86/289 (29%), Positives = 106/289 (36%), Gaps = 59/289 (20%)
Query: 9 NGICKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
N CKN + C CK GY S + A C D+DEC C C N G Y C C
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCV 463
Query: 67 PGFAPTAAGYCADVDEC-AADSMC-KGGRCVNSEGSFQCVCEAGYRPTAT---------- 114
PG+ C + DEC + C + C N+ C C+ GY T
Sbjct: 464 PGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGC 523
Query: 115 --RGACV------------------DVDECEEQRV-CRN-GRCHNTPGSFRCECLPGF-- 150
G CV D+DEC E + C N RC N PG + CEC GF
Sbjct: 524 RYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHD 583
Query: 151 --TLSNDGRTCLGL-------KLGWGVSCQACPAQGSELYAVLCPEGPS-----KDNGGA 196
T S G +C+ + W S A G + LCP GPS GG
Sbjct: 584 DGTYSLSGESCIDIDECALRTHTCWNDSACINLAGG---FDCLCPSGPSCSGDCPHEGGL 640
Query: 197 DIN--ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECD 243
N T C SC++ + R +P AD C ECD
Sbjct: 641 KHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFC--CPECD 687
Score = 76.2 bits (179), Expect = 2e-13
Identities = 65/229 (28%), Positives = 96/229 (41%), Gaps = 20/229 (8%)
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDECE-EQRVCR-N 132
+CA+ +C +S CK N++ + C C++GY A C D+DEC + C N
Sbjct: 394 FCAEGPKCGENSECKNW---NTKAT--CECKSGYISVQGDSAYCEDIDECAAKMHYCHAN 448
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQACPAQGSELYAVLCPEGPSK 191
C N PG +RC+C+PG+ +D + G G +C + + C P
Sbjct: 449 TVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
Query: 192 DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAG 251
G I G G+C + P +C+C G+ +DIDEC C
Sbjct: 509 VGNGT-ICRAFCEEGCRYGGTC--VAPN-KCVCPSGF--TGSHCEKDIDECSEGIIECHN 562
Query: 252 -GQCRNTAGSFTCVCPEGTRHEPELQL----CRDIDECEGETETHYIES 295
+C N G + C C G + L C DIDEC T T + +S
Sbjct: 563 HSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDS 611
Score = 50.8 bits (116), Expect = 1e-05
Identities = 21/38 (55%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPG 441
D A C D+DECA C T CVN G YRCDC PG
Sbjct: 428 DSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPG 465
Score = 49.2 bits (112), Expect = 3e-05
Identities = 65/247 (26%), Positives = 85/247 (34%), Gaps = 47/247 (19%)
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECEGETETHYI 293
+CR + C +C+N TC C G + + C DIDEC + HY
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKM--HYC 445
Query: 294 ESD--------YERGDIPPTF--------PTRTELASP---CD-NGRCINTHGGFECECE 333
++ R D P + E S CD N C NT G C C+
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCK 505
Query: 334 LGYVLDATAQR--CLDNRR--GSCWRRVVDGQCEAAAPELLLRQECC-----CSVGLAWG 384
GYV + T R C + R G+C V +C P C CS G+
Sbjct: 506 PGYVGNGTICRAFCEEGCRYGGTC---VAPNKC--VCPSGFTGSHCEKDIDECSEGIIEC 560
Query: 385 SXXXXXXXX---------XXXXXKGFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSY 434
G L G +C D+DECAL C C+N G +
Sbjct: 561 HNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGF 620
Query: 435 RCDCPPG 441
C CP G
Sbjct: 621 DCLCPSG 627
Score = 35.5 bits (78), Expect = 0.39
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDST 447
G+ ++D +C + DEC C C NT + C C PG + T
Sbjct: 465 GYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 513
>BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 118 bits (284), Expect = 4e-26
Identities = 81/250 (32%), Positives = 108/250 (43%), Gaps = 26/250 (10%)
Query: 35 LCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA--AGYCADVDECAAD-SMCKG 91
+CR + C + P+ C+N TC C+ G+ + YC D+DECAA C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 92 GR-CVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVC-RNGRCHNTPGSFRCECLP 148
CVN G ++C C GY +C + DEC Q C N C NT C C P
Sbjct: 448 NTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 149 GFTLSNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVP 205
G+ +G C +G +C A P + +CP G + + DI+EC+
Sbjct: 507 GYV--GNGTICRAFCEEGCRYGGTCVA-PNK------CVCPSGFTGSHCEKDIDECSEGI 557
Query: 206 GAC-PHGSCENLEPGYRCICDPGYHPD-----ADGLCRDIDECDMHQSYC-AGGQCRNTA 258
C H C NL Y C C G+H D + C DIDEC + C C N A
Sbjct: 558 IECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLA 617
Query: 259 GSFTCVCPEG 268
G F C+CP G
Sbjct: 618 GGFDCLCPSG 627
Score = 81.8 bits (193), Expect = 5e-15
Identities = 86/289 (29%), Positives = 106/289 (36%), Gaps = 59/289 (20%)
Query: 9 NGICKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
N CKN + C CK GY S + A C D+DEC C C N G Y C C
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCV 463
Query: 67 PGFAPTAAGYCADVDEC-AADSMC-KGGRCVNSEGSFQCVCEAGYRPTAT---------- 114
PG+ C + DEC + C + C N+ C C+ GY T
Sbjct: 464 PGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGC 523
Query: 115 --RGACV------------------DVDECEEQRV-CRN-GRCHNTPGSFRCECLPGF-- 150
G CV D+DEC E + C N RC N PG + CEC GF
Sbjct: 524 RYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHD 583
Query: 151 --TLSNDGRTCLGL-------KLGWGVSCQACPAQGSELYAVLCPEGPS-----KDNGGA 196
T S G +C+ + W S A G + LCP GPS GG
Sbjct: 584 DGTYSLSGESCIDIDECALRTHTCWNDSACINLAGG---FDCLCPSGPSCSGDCPHEGGL 640
Query: 197 DIN--ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECD 243
N T C SC++ + R +P AD C ECD
Sbjct: 641 KHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFC--CPECD 687
Score = 76.2 bits (179), Expect = 2e-13
Identities = 65/229 (28%), Positives = 96/229 (41%), Gaps = 20/229 (8%)
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDECE-EQRVCR-N 132
+CA+ +C +S CK N++ + C C++GY A C D+DEC + C N
Sbjct: 394 FCAEGPKCGENSECKNW---NTKAT--CECKSGYISVQGDSAYCEDIDECAAKMHYCHAN 448
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQACPAQGSELYAVLCPEGPSK 191
C N PG +RC+C+PG+ +D + G G +C + + C P
Sbjct: 449 TVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
Query: 192 DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAG 251
G I G G+C + P +C+C G+ +DIDEC C
Sbjct: 509 VGNGT-ICRAFCEEGCRYGGTC--VAPN-KCVCPSGF--TGSHCEKDIDECSEGIIECHN 562
Query: 252 -GQCRNTAGSFTCVCPEGTRHEPELQL----CRDIDECEGETETHYIES 295
+C N G + C C G + L C DIDEC T T + +S
Sbjct: 563 HSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDS 611
Score = 50.8 bits (116), Expect = 1e-05
Identities = 21/38 (55%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPG 441
D A C D+DECA C T CVN G YRCDC PG
Sbjct: 428 DSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPG 465
Score = 49.2 bits (112), Expect = 3e-05
Identities = 65/247 (26%), Positives = 85/247 (34%), Gaps = 47/247 (19%)
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECEGETETHYI 293
+CR + C +C+N TC C G + + C DIDEC + HY
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKM--HYC 445
Query: 294 ESD--------YERGDIPPTF--------PTRTELASP---CD-NGRCINTHGGFECECE 333
++ R D P + E S CD N C NT G C C+
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCK 505
Query: 334 LGYVLDATAQR--CLDNRR--GSCWRRVVDGQCEAAAPELLLRQECC-----CSVGLAWG 384
GYV + T R C + R G+C V +C P C CS G+
Sbjct: 506 PGYVGNGTICRAFCEEGCRYGGTC---VAPNKC--VCPSGFTGSHCEKDIDECSEGIIEC 560
Query: 385 SXXXXXXXX---------XXXXXKGFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSY 434
G L G +C D+DECAL C C+N G +
Sbjct: 561 HNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGF 620
Query: 435 RCDCPPG 441
C CP G
Sbjct: 621 DCLCPSG 627
Score = 35.5 bits (78), Expect = 0.39
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDST 447
G+ ++D +C + DEC C C NT + C C PG + T
Sbjct: 465 GYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 513
>BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 118 bits (284), Expect = 4e-26
Identities = 81/250 (32%), Positives = 108/250 (43%), Gaps = 26/250 (10%)
Query: 35 LCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA--AGYCADVDECAAD-SMCKG 91
+CR + C + P+ C+N TC C+ G+ + YC D+DECAA C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 92 GR-CVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVC-RNGRCHNTPGSFRCECLP 148
CVN G ++C C GY +C + DEC Q C N C NT C C P
Sbjct: 448 NTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 149 GFTLSNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVP 205
G+ +G C +G +C A P + +CP G + + DI+EC+
Sbjct: 507 GYV--GNGTICRAFCEEGCRYGGTCVA-PNK------CVCPSGFTGSHCEKDIDECSEGI 557
Query: 206 GAC-PHGSCENLEPGYRCICDPGYHPD-----ADGLCRDIDECDMHQSYC-AGGQCRNTA 258
C H C NL Y C C G+H D + C DIDEC + C C N A
Sbjct: 558 IECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLA 617
Query: 259 GSFTCVCPEG 268
G F C+CP G
Sbjct: 618 GGFDCLCPSG 627
Score = 81.8 bits (193), Expect = 5e-15
Identities = 86/289 (29%), Positives = 106/289 (36%), Gaps = 59/289 (20%)
Query: 9 NGICKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
N CKN + C CK GY S + A C D+DEC C C N G Y C C
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCV 463
Query: 67 PGFAPTAAGYCADVDEC-AADSMC-KGGRCVNSEGSFQCVCEAGYRPTAT---------- 114
PG+ C + DEC + C + C N+ C C+ GY T
Sbjct: 464 PGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGC 523
Query: 115 --RGACV------------------DVDECEEQRV-CRN-GRCHNTPGSFRCECLPGF-- 150
G CV D+DEC E + C N RC N PG + CEC GF
Sbjct: 524 RYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHD 583
Query: 151 --TLSNDGRTCLGL-------KLGWGVSCQACPAQGSELYAVLCPEGPS-----KDNGGA 196
T S G +C+ + W S A G + LCP GPS GG
Sbjct: 584 DGTYSLSGESCIDIDECALRTHTCWNDSACINLAGG---FDCLCPSGPSCSGDCPHEGGL 640
Query: 197 DIN--ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECD 243
N T C SC++ + R +P AD C ECD
Sbjct: 641 KHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFC--CPECD 687
Score = 76.2 bits (179), Expect = 2e-13
Identities = 65/229 (28%), Positives = 96/229 (41%), Gaps = 20/229 (8%)
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDECE-EQRVCR-N 132
+CA+ +C +S CK N++ + C C++GY A C D+DEC + C N
Sbjct: 394 FCAEGPKCGENSECKNW---NTKAT--CECKSGYISVQGDSAYCEDIDECAAKMHYCHAN 448
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQACPAQGSELYAVLCPEGPSK 191
C N PG +RC+C+PG+ +D + G G +C + + C P
Sbjct: 449 TVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
Query: 192 DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAG 251
G I G G+C + P +C+C G+ +DIDEC C
Sbjct: 509 VGNGT-ICRAFCEEGCRYGGTC--VAPN-KCVCPSGF--TGSHCEKDIDECSEGIIECHN 562
Query: 252 -GQCRNTAGSFTCVCPEGTRHEPELQL----CRDIDECEGETETHYIES 295
+C N G + C C G + L C DIDEC T T + +S
Sbjct: 563 HSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDS 611
Score = 50.8 bits (116), Expect = 1e-05
Identities = 21/38 (55%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPG 441
D A C D+DECA C T CVN G YRCDC PG
Sbjct: 428 DSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPG 465
Score = 49.2 bits (112), Expect = 3e-05
Identities = 65/247 (26%), Positives = 85/247 (34%), Gaps = 47/247 (19%)
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECEGETETHYI 293
+CR + C +C+N TC C G + + C DIDEC + HY
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKM--HYC 445
Query: 294 ESD--------YERGDIPPTF--------PTRTELASP---CD-NGRCINTHGGFECECE 333
++ R D P + E S CD N C NT G C C+
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCK 505
Query: 334 LGYVLDATAQR--CLDNRR--GSCWRRVVDGQCEAAAPELLLRQECC-----CSVGLAWG 384
GYV + T R C + R G+C V +C P C CS G+
Sbjct: 506 PGYVGNGTICRAFCEEGCRYGGTC---VAPNKC--VCPSGFTGSHCEKDIDECSEGIIEC 560
Query: 385 SXXXXXXXX---------XXXXXKGFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSY 434
G L G +C D+DECAL C C+N G +
Sbjct: 561 HNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGF 620
Query: 435 RCDCPPG 441
C CP G
Sbjct: 621 DCLCPSG 627
Score = 35.5 bits (78), Expect = 0.39
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDST 447
G+ ++D +C + DEC C C NT + C C PG + T
Sbjct: 465 GYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 513
>BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor
protein.
Length = 810
Score = 118 bits (284), Expect = 4e-26
Identities = 81/250 (32%), Positives = 108/250 (43%), Gaps = 26/250 (10%)
Query: 35 LCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA--AGYCADVDECAAD-SMCKG 91
+CR + C + P+ C+N TC C+ G+ + YC D+DECAA C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 92 GR-CVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVC-RNGRCHNTPGSFRCECLP 148
CVN G ++C C GY +C + DEC Q C N C NT C C P
Sbjct: 448 NTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 149 GFTLSNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVP 205
G+ +G C +G +C A P + +CP G + + DI+EC+
Sbjct: 507 GYV--GNGTICRAFCEEGCRYGGTCVA-PNK------CVCPSGFTGSHCEKDIDECSEGI 557
Query: 206 GAC-PHGSCENLEPGYRCICDPGYHPD-----ADGLCRDIDECDMHQSYC-AGGQCRNTA 258
C H C NL Y C C G+H D + C DIDEC + C C N A
Sbjct: 558 IECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLA 617
Query: 259 GSFTCVCPEG 268
G F C+CP G
Sbjct: 618 GGFDCLCPSG 627
Score = 81.8 bits (193), Expect = 5e-15
Identities = 86/289 (29%), Positives = 106/289 (36%), Gaps = 59/289 (20%)
Query: 9 NGICKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
N CKN + C CK GY S + A C D+DEC C C N G Y C C
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCV 463
Query: 67 PGFAPTAAGYCADVDEC-AADSMC-KGGRCVNSEGSFQCVCEAGYRPTAT---------- 114
PG+ C + DEC + C + C N+ C C+ GY T
Sbjct: 464 PGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGC 523
Query: 115 --RGACV------------------DVDECEEQRV-CRN-GRCHNTPGSFRCECLPGF-- 150
G CV D+DEC E + C N RC N PG + CEC GF
Sbjct: 524 RYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHD 583
Query: 151 --TLSNDGRTCLGL-------KLGWGVSCQACPAQGSELYAVLCPEGPS-----KDNGGA 196
T S G +C+ + W S A G + LCP GPS GG
Sbjct: 584 DGTYSLSGESCIDIDECALRTHTCWNDSACINLAGG---FDCLCPSGPSCSGDCPHEGGL 640
Query: 197 DIN--ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECD 243
N T C SC++ + R +P AD C ECD
Sbjct: 641 KHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFC--CPECD 687
Score = 76.2 bits (179), Expect = 2e-13
Identities = 65/229 (28%), Positives = 96/229 (41%), Gaps = 20/229 (8%)
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDECE-EQRVCR-N 132
+CA+ +C +S CK N++ + C C++GY A C D+DEC + C N
Sbjct: 394 FCAEGPKCGENSECKNW---NTKAT--CECKSGYISVQGDSAYCEDIDECAAKMHYCHAN 448
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQACPAQGSELYAVLCPEGPSK 191
C N PG +RC+C+PG+ +D + G G +C + + C P
Sbjct: 449 TVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
Query: 192 DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAG 251
G I G G+C + P +C+C G+ +DIDEC C
Sbjct: 509 VGNGT-ICRAFCEEGCRYGGTC--VAPN-KCVCPSGF--TGSHCEKDIDECSEGIIECHN 562
Query: 252 -GQCRNTAGSFTCVCPEGTRHEPELQL----CRDIDECEGETETHYIES 295
+C N G + C C G + L C DIDEC T T + +S
Sbjct: 563 HSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDS 611
Score = 50.8 bits (116), Expect = 1e-05
Identities = 21/38 (55%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPG 441
D A C D+DECA C T CVN G YRCDC PG
Sbjct: 428 DSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPG 465
Score = 49.2 bits (112), Expect = 3e-05
Identities = 65/247 (26%), Positives = 85/247 (34%), Gaps = 47/247 (19%)
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECEGETETHYI 293
+CR + C +C+N TC C G + + C DIDEC + HY
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKM--HYC 445
Query: 294 ESD--------YERGDIPPTF--------PTRTELASP---CD-NGRCINTHGGFECECE 333
++ R D P + E S CD N C NT G C C+
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCK 505
Query: 334 LGYVLDATAQR--CLDNRR--GSCWRRVVDGQCEAAAPELLLRQECC-----CSVGLAWG 384
GYV + T R C + R G+C V +C P C CS G+
Sbjct: 506 PGYVGNGTICRAFCEEGCRYGGTC---VAPNKC--VCPSGFTGSHCEKDIDECSEGIIEC 560
Query: 385 SXXXXXXXX---------XXXXXKGFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSY 434
G L G +C D+DECAL C C+N G +
Sbjct: 561 HNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGF 620
Query: 435 RCDCPPG 441
C CP G
Sbjct: 621 DCLCPSG 627
Score = 35.5 bits (78), Expect = 0.39
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDST 447
G+ ++D +C + DEC C C NT + C C PG + T
Sbjct: 465 GYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 513
>AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS
protein.
Length = 287
Score = 118 bits (284), Expect = 4e-26
Identities = 65/158 (41%), Positives = 86/158 (54%), Gaps = 27/158 (17%)
Query: 12 CKNIDGGFECICKPGYE--SGSEGA------LCRDVDECRDNPRVCRR-GRCRNTAGSYT 62
C N +G ++C+C PGYE SG++ C+DVDEC+ NPR+C+ G C NT GSYT
Sbjct: 77 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 136
Query: 63 CLCEPGFAPTAAGYCADVDEC-AADSMCKGG-RCVNSEGSFQCVCEAGYRPT------AT 114
C C PGF DV+EC + + C C+N+ GS+QC C G++P
Sbjct: 137 CQCLPGF--------KDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPN 188
Query: 115 RGACVDVDECEE-QRVCRNGR-CHNTPGSFRCECLPGF 150
C DVDEC Q C + C NT GS+ C C PG+
Sbjct: 189 NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 226
Score = 93.9 bits (223), Expect = 1e-18
Identities = 65/192 (33%), Positives = 88/192 (45%), Gaps = 29/192 (15%)
Query: 63 CLCEPGFAPTAAGYCA-DVDECAADSMCKGGR---CVNSEGSFQCVCEAGYRPTA----- 113
C C PGF+ + D++ECA S G+ C N+EGS+ CVC GY P +
Sbjct: 42 CRCNPGFSSFSEIITTPDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTF 101
Query: 114 ---TRGACVDVDECEEQ-RVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV 168
+ C DVDEC++ R+C++ G C NT GS+ C+CLPGF D C +
Sbjct: 102 KNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGF---KDVNECTSGQNPCHS 158
Query: 169 SCQACPAQGSELYAVLCPEG----PSKDNGG-----ADINECTAVPGACPHGS-CENLEP 218
S GS Y C G P NG D++EC++ C + C N
Sbjct: 159 STHCLNNVGS--YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVG 216
Query: 219 GYRCICDPGYHP 230
Y C C PG+ P
Sbjct: 217 SYSCRCRPGWKP 228
Score = 72.1 bits (169), Expect = 4e-12
Identities = 57/197 (28%), Positives = 76/197 (38%), Gaps = 33/197 (16%)
Query: 173 CPAQGSELYAVLCPEGPSKDNGGA-----DINECTAVPG-ACPHGS-CENLEPGYRCICD 225
CP S + A C P + DINEC + +C S C N E Y C+C
Sbjct: 30 CPQDSSCVNATACRCNPGFSSFSEIITTPDINECATLSKVSCGKFSDCWNTEGSYDCVCS 89
Query: 226 PGYHP---------DADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEGTRHEPEL 275
PGY P +++ C+D+DEC + C G C NT GS+TC C G + E
Sbjct: 90 PGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKDVNEC 149
Query: 276 ----QLCRDIDECEGETETHYIESDYERGDIP--PTFPTRT--ELASPCDNGR------- 320
C C ++ IP P P T E C +G+
Sbjct: 150 TSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSST 209
Query: 321 -CINTHGGFECECELGY 336
C NT G + C C G+
Sbjct: 210 VCFNTVGSYSCRCRPGW 226
Score = 70.5 bits (165), Expect = 1e-11
Identities = 40/120 (33%), Positives = 53/120 (44%), Gaps = 20/120 (16%)
Query: 3 NGGMCTN-GICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGS 60
N +C + G C N G + C C PG+ +DV+EC C C N GS
Sbjct: 118 NPRLCKSYGTCVNTLGSYTCQCLPGF---------KDVNECTSGQNPCHSSTHCLNNVGS 168
Query: 61 YTCLCEPGFAPTAAG-------YCADVDECAA-DSMCKGGR-CVNSEGSFQCVCEAGYRP 111
Y C C PG+ P C DVDEC++ C C N+ GS+ C C G++P
Sbjct: 169 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 228
Score = 52.0 bits (119), Expect = 4e-06
Identities = 24/44 (54%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 399 KGFAKLDGATCRDVDECALSAELCAG-GTCVNTDGSYRCDCPPG 441
K F TC+DVDEC + LC GTCVNT GSY C C PG
Sbjct: 99 KTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG 142
Score = 42.7 bits (96), Expect = 0.003
Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPG 441
+ C DVDEC+ C T C NT GSY C C PG
Sbjct: 188 NNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 225
Score = 37.5 bits (83), Expect = 0.097
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 23/122 (18%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C NT G ++C C GY + A+ + +C + VD +C+ P L C
Sbjct: 77 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC--QDVD-ECQQN-PRL-------CK-- 123
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCP 439
++G+ GF +DV+EC C T C+N GSY+C C
Sbjct: 124 -SYGTCVNTLGSYTCQCLPGF--------KDVNECTSGQNPCHSSTHCLNNVGSYQCRCR 174
Query: 440 PG 441
PG
Sbjct: 175 PG 176
Score = 37.1 bits (82), Expect = 0.13
Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 2/36 (5%)
Query: 408 TCRDVDECALSAELCAG--GTCVNTDGSYRCDCPPG 441
T D++ECA +++ G C NT+GSY C C PG
Sbjct: 56 TTPDINECATLSKVSCGKFSDCWNTEGSYDCVCSPG 91
>U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein.
Length = 652
Score = 118 bits (283), Expect = 6e-26
Identities = 65/147 (44%), Positives = 80/147 (54%), Gaps = 11/147 (7%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP--TAAGY 76
+ C C GY+ S C DVDEC+D+P C + C NT G + C C G+ P G
Sbjct: 326 YTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGA 382
Query: 77 CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDEC--EEQRVCRN 132
C DVDECA S C G C N++GSF C CE GY G C DVDEC +C +
Sbjct: 383 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-D 440
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTC 159
C NT GSF C CLPG+ L+ +G +C
Sbjct: 441 SLCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 106 bits (255), Expect = 1e-22
Identities = 65/164 (39%), Positives = 79/164 (48%), Gaps = 12/164 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RC--RNTAG 59
N G C + DG F C C+PG+ + C + C +P CR G C
Sbjct: 267 NNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGK 324
Query: 60 SYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTAT-RGA 117
+YTC C G+ ++ C DVDEC DS C CVN+ G F+C C GY P GA
Sbjct: 325 NYTCRCPQGYQLDSSQLDCVDVDEC-QDSPC-AQECVNTPGGFRCECWVGYEPGGPGEGA 382
Query: 118 CVDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLS-NDGRTC 159
C DVDEC R C G C NT GSF C C G+ L+ DG C
Sbjct: 383 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQC 425
Score = 99.5 bits (237), Expect = 2e-20
Identities = 82/232 (35%), Positives = 98/232 (42%), Gaps = 50/232 (21%)
Query: 132 NGRCHNT-----PGSFRCECLPGFTLSNDGRTCLGLK------LGWGVSCQACPAQGSEL 180
NG CH GSF C C PGF L +D TC G +C P G
Sbjct: 268 NGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGP-HGKN- 325
Query: 181 YAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA--DGL 235
Y CP+G D+ D++EC P A C N G+RC C GY P +G
Sbjct: 326 YTCRCPQGYQLDSSQLDCVDVDECQDSPCA---QECVNTPGGFRCECWVGYEPGGPGEGA 382
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG--TRHEPELQLCRDIDECEGETETHYI 293
C+D+DEC + +S CA G C NT GSF C C EG E Q C+D+DEC G
Sbjct: 383 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQ-CQDVDECVG------- 433
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
P P CD+ C NT G F C C G+VL C
Sbjct: 434 ----------PGGPL-------CDS-LCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 90.6 bits (215), Expect = 1e-17
Identities = 67/215 (31%), Positives = 95/215 (44%), Gaps = 17/215 (7%)
Query: 27 YESGSEGALCRDVDE-CRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
++ GS G LC C N C + GS+ C C PGF CA + C+
Sbjct: 248 FDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCS 307
Query: 85 ADSMCKGGR-CV-NSEG-SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
+ S C+GG CV G ++ C C GY+ +++ CVDVDEC++ + C NTPG
Sbjct: 308 S-SPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ--ECVNTPGG 364
Query: 142 FRCECLPGFTLSNDGR-TCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG 195
FRCEC G+ G C + LG Q C + C EG + ++G
Sbjct: 365 FRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHC-SCEEGYVLAGEDGT 423
Query: 196 --ADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
D++EC G C N + + C C PG+
Sbjct: 424 QCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 70.9 bits (166), Expect = 8e-12
Identities = 54/181 (29%), Positives = 72/181 (39%), Gaps = 13/181 (7%)
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR-CHNTPG--SFRCECLPGFTLSN 154
+GSF C C G+R C + C CR G C P ++ C C G+ L +
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP-CRGGATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 155 DGRTCLGLKLGWGVSC-QACP-AQGS---ELYAVLCPEGPSKDNGGADINECTAVPGACP 209
C+ + C Q C G E + P GP + D++EC C
Sbjct: 339 SQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPG-EGACQDVDECALGRSPCA 397
Query: 210 HGSCENLEPGYRCICDPGYH-PDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
G C N + + C C+ GY DG C+D+DEC C NT GSF C C
Sbjct: 398 QG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLP 456
Query: 268 G 268
G
Sbjct: 457 G 457
Score = 54.8 bits (126), Expect = 6e-07
Identities = 46/135 (34%), Positives = 55/135 (40%), Gaps = 28/135 (20%)
Query: 313 ASPCDNGR-CI-NTHG-GFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPEL 369
+SPC G C+ HG + C C GY LD++ C+D C D C
Sbjct: 308 SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDV--DECQ----DSPCAQECVNT 361
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C VG G +GA C+DVDECAL CA G C N
Sbjct: 362 PGGFRCECWVGYEPGGPG-----------------EGA-CQDVDECALGRSPCAQG-CTN 402
Query: 430 TDGSYRCDCPPGLTL 444
TDGS+ C C G L
Sbjct: 403 TDGSFHCSCEEGYVL 417
Score = 54.4 bits (125), Expect = 8e-07
Identities = 67/251 (26%), Positives = 90/251 (35%), Gaps = 49/251 (19%)
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGS 260
C G C E + + C C PG+ L D+ C ++ C+ CR G
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFR-----LLDDLVTC-ASRNPCSSSPCR---GG 314
Query: 261 FTCVC-PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG 319
TCV P G + +D ++ ++ D E D SPC
Sbjct: 315 ATCVLGPHGKNYTCRCPQGYQLDS----SQLDCVDVD-ECQD------------SPCAQ- 356
Query: 320 RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSV 379
C+NT GGF CEC +GY + G+C + VD +C L R C
Sbjct: 357 ECVNTPGGFRCECWVGYEPGGPGE-------GAC--QDVD-ECA------LGRSPCAQGC 400
Query: 380 GLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
GS + DG C+DVDEC C NT GS+ C C
Sbjct: 401 TNTDGSFHCSCEEGYVLAGE-----DGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCL 455
Query: 440 PGLTLDSTGTA 450
PG L G +
Sbjct: 456 PGWVLAPNGVS 466
Score = 31.9 bits (69), Expect = 4.8
Identities = 12/33 (36%), Positives = 15/33 (45%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALC 36
GG + +C N G F C C PG+ G C
Sbjct: 435 GGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
>BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein.
Length = 652
Score = 118 bits (283), Expect = 6e-26
Identities = 65/147 (44%), Positives = 80/147 (54%), Gaps = 11/147 (7%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP--TAAGY 76
+ C C GY+ S C DVDEC+D+P C + C NT G + C C G+ P G
Sbjct: 326 YTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGA 382
Query: 77 CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDEC--EEQRVCRN 132
C DVDECA S C G C N++GSF C CE GY G C DVDEC +C +
Sbjct: 383 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-D 440
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTC 159
C NT GSF C CLPG+ L+ +G +C
Sbjct: 441 SLCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 106 bits (255), Expect = 1e-22
Identities = 65/164 (39%), Positives = 79/164 (48%), Gaps = 12/164 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RC--RNTAG 59
N G C + DG F C C+PG+ + C + C +P CR G C
Sbjct: 267 NNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGK 324
Query: 60 SYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTAT-RGA 117
+YTC C G+ ++ C DVDEC DS C CVN+ G F+C C GY P GA
Sbjct: 325 NYTCRCPQGYQLDSSQLDCVDVDEC-QDSPC-AQECVNTPGGFRCECWVGYEPGGPGEGA 382
Query: 118 CVDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLS-NDGRTC 159
C DVDEC R C G C NT GSF C C G+ L+ DG C
Sbjct: 383 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQC 425
Score = 99.5 bits (237), Expect = 2e-20
Identities = 82/232 (35%), Positives = 98/232 (42%), Gaps = 50/232 (21%)
Query: 132 NGRCHNT-----PGSFRCECLPGFTLSNDGRTCLGLK------LGWGVSCQACPAQGSEL 180
NG CH GSF C C PGF L +D TC G +C P G
Sbjct: 268 NGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGP-HGKN- 325
Query: 181 YAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA--DGL 235
Y CP+G D+ D++EC P A C N G+RC C GY P +G
Sbjct: 326 YTCRCPQGYQLDSSQLDCVDVDECQDSPCA---QECVNTPGGFRCECWVGYEPGGPGEGA 382
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG--TRHEPELQLCRDIDECEGETETHYI 293
C+D+DEC + +S CA G C NT GSF C C EG E Q C+D+DEC G
Sbjct: 383 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQ-CQDVDECVG------- 433
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
P P CD+ C NT G F C C G+VL C
Sbjct: 434 ----------PGGPL-------CDS-LCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 90.6 bits (215), Expect = 1e-17
Identities = 67/215 (31%), Positives = 95/215 (44%), Gaps = 17/215 (7%)
Query: 27 YESGSEGALCRDVDE-CRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
++ GS G LC C N C + GS+ C C PGF CA + C+
Sbjct: 248 FDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCS 307
Query: 85 ADSMCKGGR-CV-NSEG-SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
+ S C+GG CV G ++ C C GY+ +++ CVDVDEC++ + C NTPG
Sbjct: 308 S-SPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ--ECVNTPGG 364
Query: 142 FRCECLPGFTLSNDGR-TCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG 195
FRCEC G+ G C + LG Q C + C EG + ++G
Sbjct: 365 FRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHC-SCEEGYVLAGEDGT 423
Query: 196 --ADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
D++EC G C N + + C C PG+
Sbjct: 424 QCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 70.9 bits (166), Expect = 8e-12
Identities = 54/181 (29%), Positives = 72/181 (39%), Gaps = 13/181 (7%)
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR-CHNTPG--SFRCECLPGFTLSN 154
+GSF C C G+R C + C CR G C P ++ C C G+ L +
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP-CRGGATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 155 DGRTCLGLKLGWGVSC-QACP-AQGS---ELYAVLCPEGPSKDNGGADINECTAVPGACP 209
C+ + C Q C G E + P GP + D++EC C
Sbjct: 339 SQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPG-EGACQDVDECALGRSPCA 397
Query: 210 HGSCENLEPGYRCICDPGYH-PDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
G C N + + C C+ GY DG C+D+DEC C NT GSF C C
Sbjct: 398 QG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLP 456
Query: 268 G 268
G
Sbjct: 457 G 457
Score = 54.8 bits (126), Expect = 6e-07
Identities = 46/135 (34%), Positives = 55/135 (40%), Gaps = 28/135 (20%)
Query: 313 ASPCDNGR-CI-NTHG-GFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPEL 369
+SPC G C+ HG + C C GY LD++ C+D C D C
Sbjct: 308 SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDV--DECQ----DSPCAQECVNT 361
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C VG G +GA C+DVDECAL CA G C N
Sbjct: 362 PGGFRCECWVGYEPGGPG-----------------EGA-CQDVDECALGRSPCAQG-CTN 402
Query: 430 TDGSYRCDCPPGLTL 444
TDGS+ C C G L
Sbjct: 403 TDGSFHCSCEEGYVL 417
Score = 54.4 bits (125), Expect = 8e-07
Identities = 67/251 (26%), Positives = 90/251 (35%), Gaps = 49/251 (19%)
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGS 260
C G C E + + C C PG+ L D+ C ++ C+ CR G
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFR-----LLDDLVTC-ASRNPCSSSPCR---GG 314
Query: 261 FTCVC-PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG 319
TCV P G + +D ++ ++ D E D SPC
Sbjct: 315 ATCVLGPHGKNYTCRCPQGYQLDS----SQLDCVDVD-ECQD------------SPCAQ- 356
Query: 320 RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSV 379
C+NT GGF CEC +GY + G+C + VD +C L R C
Sbjct: 357 ECVNTPGGFRCECWVGYEPGGPGE-------GAC--QDVD-ECA------LGRSPCAQGC 400
Query: 380 GLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
GS + DG C+DVDEC C NT GS+ C C
Sbjct: 401 TNTDGSFHCSCEEGYVLAGE-----DGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCL 455
Query: 440 PGLTLDSTGTA 450
PG L G +
Sbjct: 456 PGWVLAPNGVS 466
Score = 31.9 bits (69), Expect = 4.8
Identities = 12/33 (36%), Positives = 15/33 (45%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALC 36
GG + +C N G F C C PG+ G C
Sbjct: 435 GGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
>AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1, q
subcomponent, receptor 1 protein.
Length = 652
Score = 118 bits (283), Expect = 6e-26
Identities = 65/147 (44%), Positives = 80/147 (54%), Gaps = 11/147 (7%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP--TAAGY 76
+ C C GY+ S C DVDEC+D+P C + C NT G + C C G+ P G
Sbjct: 326 YTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGA 382
Query: 77 CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDEC--EEQRVCRN 132
C DVDECA S C G C N++GSF C CE GY G C DVDEC +C +
Sbjct: 383 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-D 440
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTC 159
C NT GSF C CLPG+ L+ +G +C
Sbjct: 441 SLCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 106 bits (255), Expect = 1e-22
Identities = 65/164 (39%), Positives = 79/164 (48%), Gaps = 12/164 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RC--RNTAG 59
N G C + DG F C C+PG+ + C + C +P CR G C
Sbjct: 267 NNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGK 324
Query: 60 SYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTAT-RGA 117
+YTC C G+ ++ C DVDEC DS C CVN+ G F+C C GY P GA
Sbjct: 325 NYTCRCPQGYQLDSSQLDCVDVDEC-QDSPC-AQECVNTPGGFRCECWVGYEPGGPGEGA 382
Query: 118 CVDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLS-NDGRTC 159
C DVDEC R C G C NT GSF C C G+ L+ DG C
Sbjct: 383 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQC 425
Score = 99.5 bits (237), Expect = 2e-20
Identities = 82/232 (35%), Positives = 98/232 (42%), Gaps = 50/232 (21%)
Query: 132 NGRCHNT-----PGSFRCECLPGFTLSNDGRTCLGLK------LGWGVSCQACPAQGSEL 180
NG CH GSF C C PGF L +D TC G +C P G
Sbjct: 268 NGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGP-HGKN- 325
Query: 181 YAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA--DGL 235
Y CP+G D+ D++EC P A C N G+RC C GY P +G
Sbjct: 326 YTCRCPQGYQLDSSQLDCVDVDECQDSPCA---QECVNTPGGFRCECWVGYEPGGPGEGA 382
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG--TRHEPELQLCRDIDECEGETETHYI 293
C+D+DEC + +S CA G C NT GSF C C EG E Q C+D+DEC G
Sbjct: 383 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQ-CQDVDECVG------- 433
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
P P CD+ C NT G F C C G+VL C
Sbjct: 434 ----------PGGPL-------CDS-LCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 90.6 bits (215), Expect = 1e-17
Identities = 67/215 (31%), Positives = 95/215 (44%), Gaps = 17/215 (7%)
Query: 27 YESGSEGALCRDVDE-CRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
++ GS G LC C N C + GS+ C C PGF CA + C+
Sbjct: 248 FDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCS 307
Query: 85 ADSMCKGGR-CV-NSEG-SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
+ S C+GG CV G ++ C C GY+ +++ CVDVDEC++ + C NTPG
Sbjct: 308 S-SPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ--ECVNTPGG 364
Query: 142 FRCECLPGFTLSNDGR-TCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG 195
FRCEC G+ G C + LG Q C + C EG + ++G
Sbjct: 365 FRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHC-SCEEGYVLAGEDGT 423
Query: 196 --ADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
D++EC G C N + + C C PG+
Sbjct: 424 QCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 70.9 bits (166), Expect = 8e-12
Identities = 54/181 (29%), Positives = 72/181 (39%), Gaps = 13/181 (7%)
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR-CHNTPG--SFRCECLPGFTLSN 154
+GSF C C G+R C + C CR G C P ++ C C G+ L +
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP-CRGGATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 155 DGRTCLGLKLGWGVSC-QACP-AQGS---ELYAVLCPEGPSKDNGGADINECTAVPGACP 209
C+ + C Q C G E + P GP + D++EC C
Sbjct: 339 SQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPG-EGACQDVDECALGRSPCA 397
Query: 210 HGSCENLEPGYRCICDPGYH-PDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
G C N + + C C+ GY DG C+D+DEC C NT GSF C C
Sbjct: 398 QG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLP 456
Query: 268 G 268
G
Sbjct: 457 G 457
Score = 54.8 bits (126), Expect = 6e-07
Identities = 46/135 (34%), Positives = 55/135 (40%), Gaps = 28/135 (20%)
Query: 313 ASPCDNGR-CI-NTHG-GFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPEL 369
+SPC G C+ HG + C C GY LD++ C+D C D C
Sbjct: 308 SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDV--DECQ----DSPCAQECVNT 361
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C VG G +GA C+DVDECAL CA G C N
Sbjct: 362 PGGFRCECWVGYEPGGPG-----------------EGA-CQDVDECALGRSPCAQG-CTN 402
Query: 430 TDGSYRCDCPPGLTL 444
TDGS+ C C G L
Sbjct: 403 TDGSFHCSCEEGYVL 417
Score = 54.4 bits (125), Expect = 8e-07
Identities = 67/251 (26%), Positives = 90/251 (35%), Gaps = 49/251 (19%)
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGS 260
C G C E + + C C PG+ L D+ C ++ C+ CR G
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFR-----LLDDLVTC-ASRNPCSSSPCR---GG 314
Query: 261 FTCVC-PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG 319
TCV P G + +D ++ ++ D E D SPC
Sbjct: 315 ATCVLGPHGKNYTCRCPQGYQLDS----SQLDCVDVD-ECQD------------SPCAQ- 356
Query: 320 RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSV 379
C+NT GGF CEC +GY + G+C + VD +C L R C
Sbjct: 357 ECVNTPGGFRCECWVGYEPGGPGE-------GAC--QDVD-ECA------LGRSPCAQGC 400
Query: 380 GLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
GS + DG C+DVDEC C NT GS+ C C
Sbjct: 401 TNTDGSFHCSCEEGYVLAGE-----DGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCL 455
Query: 440 PGLTLDSTGTA 450
PG L G +
Sbjct: 456 PGWVLAPNGVS 466
Score = 31.9 bits (69), Expect = 4.8
Identities = 12/33 (36%), Positives = 15/33 (45%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALC 36
GG + +C N G F C C PG+ G C
Sbjct: 435 GGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
>AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein
protein.
Length = 652
Score = 118 bits (283), Expect = 6e-26
Identities = 65/147 (44%), Positives = 80/147 (54%), Gaps = 11/147 (7%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP--TAAGY 76
+ C C GY+ S C DVDEC+D+P C + C NT G + C C G+ P G
Sbjct: 326 YTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGA 382
Query: 77 CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDEC--EEQRVCRN 132
C DVDECA S C G C N++GSF C CE GY G C DVDEC +C +
Sbjct: 383 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-D 440
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTC 159
C NT GSF C CLPG+ L+ +G +C
Sbjct: 441 SLCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 107 bits (256), Expect = 1e-22
Identities = 65/164 (39%), Positives = 79/164 (48%), Gaps = 12/164 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCR--NTAG 59
N G C + DG F C C+PG+ + C + C +P CR G C
Sbjct: 267 NNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCALGPHGK 324
Query: 60 SYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTAT-RGA 117
+YTC C G+ ++ C DVDEC DS C CVN+ G F+C C GY P GA
Sbjct: 325 NYTCRCPQGYQLDSSQLDCVDVDEC-QDSPC-AQECVNTPGGFRCECWVGYEPGGPGEGA 382
Query: 118 CVDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLS-NDGRTC 159
C DVDEC R C G C NT GSF C C G+ L+ DG C
Sbjct: 383 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQC 425
Score = 100 bits (240), Expect = 9e-21
Identities = 82/230 (35%), Positives = 99/230 (43%), Gaps = 46/230 (20%)
Query: 132 NGRCHNT-----PGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ--ACPAQG--SELYA 182
NG CH GSF C C PGF L +D TC C+ A A G + Y
Sbjct: 268 NGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHGKNYT 327
Query: 183 VLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA--DGLCR 237
CP+G D+ D++EC P A C N G+RC C GY P +G C+
Sbjct: 328 CRCPQGYQLDSSQLDCVDVDECQDSPCA---QECVNTPGGFRCECWVGYEPGGPGEGACQ 384
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCPEG--TRHEPELQLCRDIDECEGETETHYIES 295
D+DEC + +S CA G C NT GSF C C EG E Q C+D+DEC G
Sbjct: 385 DVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQ-CQDVDECVG--------- 433
Query: 296 DYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
P P CD+ C NT G F C C G+VL C
Sbjct: 434 --------PGGPL-------CDS-LCFNTQGSFHCGCLPGWVLAPNGVSC 467
Score = 89.4 bits (212), Expect = 2e-17
Identities = 65/215 (30%), Positives = 94/215 (43%), Gaps = 17/215 (7%)
Query: 27 YESGSEGALCRDVDE-CRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
++ GS G LC C N C + GS+ C C PGF CA + C+
Sbjct: 248 FDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCS 307
Query: 85 ADSMCKGGR--CVNSEG-SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
+ S C+GG + G ++ C C GY+ +++ CVDVDEC++ + C NTPG
Sbjct: 308 S-SPCRGGATCALGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ--ECVNTPGG 364
Query: 142 FRCECLPGFTLSNDGR-TCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG 195
FRCEC G+ G C + LG Q C + C EG + ++G
Sbjct: 365 FRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHC-SCEEGYVLAGEDGT 423
Query: 196 --ADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
D++EC G C N + + C C PG+
Sbjct: 424 QCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 71.3 bits (167), Expect = 6e-12
Identities = 54/181 (29%), Positives = 72/181 (39%), Gaps = 13/181 (7%)
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR-CHNTPG--SFRCECLPGFTLSN 154
+GSF C C G+R C + C CR G C P ++ C C G+ L +
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP-CRGGATCALGPHGKNYTCRCPQGYQLDS 338
Query: 155 DGRTCLGLKLGWGVSC-QACP-AQGS---ELYAVLCPEGPSKDNGGADINECTAVPGACP 209
C+ + C Q C G E + P GP + D++EC C
Sbjct: 339 SQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPG-EGACQDVDECALGRSPCA 397
Query: 210 HGSCENLEPGYRCICDPGYH-PDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
G C N + + C C+ GY DG C+D+DEC C NT GSF C C
Sbjct: 398 QG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLP 456
Query: 268 G 268
G
Sbjct: 457 G 457
Score = 54.4 bits (125), Expect = 8e-07
Identities = 45/135 (33%), Positives = 54/135 (40%), Gaps = 28/135 (20%)
Query: 313 ASPCDNGR--CINTHG-GFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPEL 369
+SPC G + HG + C C GY LD++ C+D C D C
Sbjct: 308 SSPCRGGATCALGPHGKNYTCRCPQGYQLDSSQLDCVDV--DECQ----DSPCAQECVNT 361
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C VG G +GA C+DVDECAL CA G C N
Sbjct: 362 PGGFRCECWVGYEPGGPG-----------------EGA-CQDVDECALGRSPCAQG-CTN 402
Query: 430 TDGSYRCDCPPGLTL 444
TDGS+ C C G L
Sbjct: 403 TDGSFHCSCEEGYVL 417
Score = 53.6 bits (123), Expect = 1e-06
Identities = 43/137 (31%), Positives = 53/137 (38%), Gaps = 22/137 (16%)
Query: 314 SPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ 373
SPC C+NT GGF CEC +GY + G+C + VD +C L R
Sbjct: 352 SPCAQ-ECVNTPGGFRCECWVGYEPGGPGE-------GAC--QDVD-ECA------LGRS 394
Query: 374 ECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGS 433
C GS + DG C+DVDEC C NT GS
Sbjct: 395 PCAQGCTNTDGSFHCSCEEGYVLAGE-----DGTQCQDVDECVGPGGPLCDSLCFNTQGS 449
Query: 434 YRCDCPPGLTLDSTGTA 450
+ C C PG L G +
Sbjct: 450 FHCGCLPGWVLAPNGVS 466
Score = 49.6 bits (113), Expect = 2e-05
Identities = 47/157 (29%), Positives = 60/157 (38%), Gaps = 22/157 (14%)
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQ-CR--N 256
C G C E + + C C PG+ D + C + C S C GG C
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCALGP 321
Query: 257 TAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIES-----------DYERGDI-PP 304
++TC CP+G + + C D+DEC+ + YE G
Sbjct: 322 HGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEG 381
Query: 305 TFPTRTELA---SPCDNGRCINTHGGFECECELGYVL 338
E A SPC G C NT G F C CE GYVL
Sbjct: 382 ACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVL 417
Score = 31.9 bits (69), Expect = 4.8
Identities = 22/52 (42%), Positives = 27/52 (51%), Gaps = 6/52 (11%)
Query: 400 GFAKLDG-ATCRDVDECALSAELCAGG-TC-VNTDG-SYRCDCPPGLTLDST 447
GF LD TC + C+ S C GG TC + G +Y C CP G LDS+
Sbjct: 290 GFRLLDDLVTCASRNPCSSSP--CRGGATCALGPHGKNYTCRCPQGYQLDSS 339
Score = 31.9 bits (69), Expect = 4.8
Identities = 12/33 (36%), Positives = 15/33 (45%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALC 36
GG + +C N G F C C PG+ G C
Sbjct: 435 GGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
>AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1, q
subcomponent, receptor 1 variant protein.
Length = 671
Score = 118 bits (283), Expect = 6e-26
Identities = 65/147 (44%), Positives = 80/147 (54%), Gaps = 11/147 (7%)
Query: 19 FECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP--TAAGY 76
+ C C GY+ S C DVDEC+D+P C + C NT G + C C G+ P G
Sbjct: 345 YTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGA 401
Query: 77 CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDEC--EEQRVCRN 132
C DVDECA S C G C N++GSF C CE GY G C DVDEC +C +
Sbjct: 402 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-D 459
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTC 159
C NT GSF C CLPG+ L+ +G +C
Sbjct: 460 SLCFNTQGSFHCGCLPGWVLAPNGVSC 486
Score = 106 bits (255), Expect = 1e-22
Identities = 65/164 (39%), Positives = 79/164 (48%), Gaps = 12/164 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RC--RNTAG 59
N G C + DG F C C+PG+ + C + C +P CR G C
Sbjct: 286 NNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGK 343
Query: 60 SYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTAT-RGA 117
+YTC C G+ ++ C DVDEC DS C CVN+ G F+C C GY P GA
Sbjct: 344 NYTCRCPQGYQLDSSQLDCVDVDEC-QDSPC-AQECVNTPGGFRCECWVGYEPGGPGEGA 401
Query: 118 CVDVDECEEQR-VCRNGRCHNTPGSFRCECLPGFTLS-NDGRTC 159
C DVDEC R C G C NT GSF C C G+ L+ DG C
Sbjct: 402 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQC 444
Score = 99.5 bits (237), Expect = 2e-20
Identities = 82/232 (35%), Positives = 98/232 (42%), Gaps = 50/232 (21%)
Query: 132 NGRCHNT-----PGSFRCECLPGFTLSNDGRTCLGLK------LGWGVSCQACPAQGSEL 180
NG CH GSF C C PGF L +D TC G +C P G
Sbjct: 287 NGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGP-HGKN- 344
Query: 181 YAVLCPEGPSKDNGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDA--DGL 235
Y CP+G D+ D++EC P A C N G+RC C GY P +G
Sbjct: 345 YTCRCPQGYQLDSSQLDCVDVDECQDSPCA---QECVNTPGGFRCECWVGYEPGGPGEGA 401
Query: 236 CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG--TRHEPELQLCRDIDECEGETETHYI 293
C+D+DEC + +S CA G C NT GSF C C EG E Q C+D+DEC G
Sbjct: 402 CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQ-CQDVDECVG------- 452
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
P P CD+ C NT G F C C G+VL C
Sbjct: 453 ----------PGGPL-------CDS-LCFNTQGSFHCGCLPGWVLAPNGVSC 486
Score = 90.6 bits (215), Expect = 1e-17
Identities = 67/215 (31%), Positives = 95/215 (44%), Gaps = 17/215 (7%)
Query: 27 YESGSEGALCRDVDE-CRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA-AGYCADVDECA 84
++ GS G LC C N C + GS+ C C PGF CA + C+
Sbjct: 267 FDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCS 326
Query: 85 ADSMCKGGR-CV-NSEG-SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
+ S C+GG CV G ++ C C GY+ +++ CVDVDEC++ + C NTPG
Sbjct: 327 S-SPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ--ECVNTPGG 383
Query: 142 FRCECLPGFTLSNDGR-TCLGL---KLGWGVSCQACPAQGSELYAVLCPEG--PSKDNGG 195
FRCEC G+ G C + LG Q C + C EG + ++G
Sbjct: 384 FRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHC-SCEEGYVLAGEDGT 442
Query: 196 --ADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
D++EC G C N + + C C PG+
Sbjct: 443 QCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 477
Score = 70.9 bits (166), Expect = 8e-12
Identities = 54/181 (29%), Positives = 72/181 (39%), Gaps = 13/181 (7%)
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR-CHNTPG--SFRCECLPGFTLSN 154
+GSF C C G+R C + C CR G C P ++ C C G+ L +
Sbjct: 299 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSP-CRGGATCVLGPHGKNYTCRCPQGYQLDS 357
Query: 155 DGRTCLGLKLGWGVSC-QACP-AQGS---ELYAVLCPEGPSKDNGGADINECTAVPGACP 209
C+ + C Q C G E + P GP + D++EC C
Sbjct: 358 SQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPG-EGACQDVDECALGRSPCA 416
Query: 210 HGSCENLEPGYRCICDPGYH-PDADGL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
G C N + + C C+ GY DG C+D+DEC C NT GSF C C
Sbjct: 417 QG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLP 475
Query: 268 G 268
G
Sbjct: 476 G 476
Score = 54.8 bits (126), Expect = 6e-07
Identities = 46/135 (34%), Positives = 55/135 (40%), Gaps = 28/135 (20%)
Query: 313 ASPCDNGR-CI-NTHG-GFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPEL 369
+SPC G C+ HG + C C GY LD++ C+D C D C
Sbjct: 327 SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDV--DECQ----DSPCAQECVNT 380
Query: 370 LLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVN 429
C C VG G +GA C+DVDECAL CA G C N
Sbjct: 381 PGGFRCECWVGYEPGGPG-----------------EGA-CQDVDECALGRSPCAQG-CTN 421
Query: 430 TDGSYRCDCPPGLTL 444
TDGS+ C C G L
Sbjct: 422 TDGSFHCSCEEGYVL 436
Score = 54.4 bits (125), Expect = 8e-07
Identities = 67/251 (26%), Positives = 90/251 (35%), Gaps = 49/251 (19%)
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGS 260
C G C E + + C C PG+ L D+ C ++ C+ CR G
Sbjct: 283 CNFNNGGCHQDCFEGGDGSFLCGCRPGFR-----LLDDLVTC-ASRNPCSSSPCR---GG 333
Query: 261 FTCVC-PEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNG 319
TCV P G + +D ++ ++ D E D SPC
Sbjct: 334 ATCVLGPHGKNYTCRCPQGYQLDS----SQLDCVDVD-ECQD------------SPCAQ- 375
Query: 320 RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSV 379
C+NT GGF CEC +GY + G+C + VD +C L R C
Sbjct: 376 ECVNTPGGFRCECWVGYEPGGPGE-------GAC--QDVD-ECA------LGRSPCAQGC 419
Query: 380 GLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
GS + DG C+DVDEC C NT GS+ C C
Sbjct: 420 TNTDGSFHCSCEEGYVLAGE-----DGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCL 474
Query: 440 PGLTLDSTGTA 450
PG L G +
Sbjct: 475 PGWVLAPNGVS 485
Score = 31.9 bits (69), Expect = 4.8
Identities = 12/33 (36%), Positives = 15/33 (45%)
Query: 4 GGMCTNGICKNIDGGFECICKPGYESGSEGALC 36
GG + +C N G F C C PG+ G C
Sbjct: 454 GGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 486
>L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific
protein protein.
Length = 678
Score = 114 bits (274), Expect = 7e-25
Identities = 61/152 (40%), Positives = 82/152 (53%), Gaps = 11/152 (7%)
Query: 12 CKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C+++ G F C+CK G+ G LC +DV+EC C + C N GS+ C C GF
Sbjct: 133 CQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFE 187
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
++ G C D+DECA C RC N GS+ C+C+ G+ ++ AC DVDEC + R
Sbjct: 188 LSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR- 246
Query: 130 CRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
C C N+PGS+ C C G LS D TC
Sbjct: 247 CEQ-VCVNSPGSYTCHCDGRGGLKLSQDMDTC 277
Score = 102 bits (245), Expect = 2e-21
Identities = 53/125 (42%), Positives = 68/125 (54%), Gaps = 8/125 (6%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C IC N G F C C G+E S+G C+D+DEC D+ C RC+N GSY+
Sbjct: 164 NGG-CLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADS-EACGEARCKNLPGSYS 220
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCE--AGYRPTATRGACV 119
CLC+ GFA + C DVDEC C+ CVNS GS+ C C+ G + + C
Sbjct: 221 CLCDEGFAYSSQEKACRDVDEC-LQGRCE-QVCVNSPGSYTCHCDGRGGLKLSQDMDTCE 278
Query: 120 DVDEC 124
D+ C
Sbjct: 279 DILPC 283
Score = 91.9 bits (218), Expect = 4e-18
Identities = 51/147 (34%), Positives = 73/147 (49%), Gaps = 11/147 (7%)
Query: 20 ECICKPG--YESGSEGALCRD--VDECRDNPRVC-RRGR--CRNTAGSYTCLCEPGFAPT 72
+CI K G Y S A C D+C NP C R+G C++ G++ CLC+ G+
Sbjct: 94 DCINKYGSPYTKNSGFATCVQNLPDQCTPNP--CDRKGTQACQDLMGNFFCLCKAGWGGR 151
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
DV+EC+ ++ C N GSF C C +G+ ++ C D+DEC + C
Sbjct: 152 LCD--KDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGE 209
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTC 159
RC N PGS+ C C GF S+ + C
Sbjct: 210 ARCKNLPGSYSCLCDEGFAYSSQEKAC 236
Score = 82.6 bits (195), Expect = 3e-15
Identities = 43/127 (33%), Positives = 63/127 (49%), Gaps = 5/127 (3%)
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
QAC + LC G D+NEC+ G C C N + C C G+
Sbjct: 131 QACQDLMGNFFC-LCKAGWGGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFEL 188
Query: 231 DADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGET 288
+DG C+DIDEC ++ C +C+N GS++C+C EG + + + CRD+DEC +G
Sbjct: 189 SSDGRTCQDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRC 247
Query: 289 ETHYIES 295
E + S
Sbjct: 248 EQVCVNS 254
Score = 56.0 bits (129), Expect = 3e-07
Identities = 41/152 (26%), Positives = 62/152 (40%), Gaps = 23/152 (15%)
Query: 199 NECTAVPGACPHG---SCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQC 254
++CT P C +C++L + C+C G+ LC +D++EC C C
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW---GGRLCDKDVNECSQENGGCLQ-IC 171
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECE-----GETETHYIESDY----ERGDIPPT 305
N GSF C C G + + C+DIDEC GE + Y + G +
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSS 231
Query: 306 FPTRTELASPCDNGRC----INTHGGFECECE 333
C GRC +N+ G + C C+
Sbjct: 232 QEKACRDVDECLQGRCEQVCVNSPGSYTCHCD 263
Score = 47.2 bits (107), Expect = 1e-04
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
DG TC+D+DECA +E C C N GSY C C G S
Sbjct: 191 DGRTCQDIDECA-DSEACGEARCKNLPGSYSCLCDEGFAYSS 231
Score = 41.1 bits (92), Expect = 0.008
Identities = 36/118 (30%), Positives = 41/118 (34%), Gaps = 26/118 (22%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C N G F C C G+ L + + C D C G EA L C C G
Sbjct: 171 CHNKPGSFHCSCHSGFELSSDGRTCQDI--DECADSEACG--EARCKNLPGSYSCLCDEG 226
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A+ S CRDVDEC C CVN+ GSY C C
Sbjct: 227 FAYSSQEKA-------------------CRDVDECLQGR--CEQ-VCVNSPGSYTCHC 262
Score = 32.3 bits (70), Expect = 3.6
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 406 GATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C +DV+EC+ C C N GS+ C C G L S G
Sbjct: 150 GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDG 192
>BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific 6
protein.
Length = 678
Score = 114 bits (274), Expect = 7e-25
Identities = 61/152 (40%), Positives = 82/152 (53%), Gaps = 11/152 (7%)
Query: 12 CKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C+++ G F C+CK G+ G LC +DV+EC C + C N GS+ C C GF
Sbjct: 133 CQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFE 187
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
++ G C D+DECA C RC N GS+ C+C+ G+ ++ AC DVDEC + R
Sbjct: 188 LSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR- 246
Query: 130 CRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
C C N+PGS+ C C G LS D TC
Sbjct: 247 CEQ-VCVNSPGSYTCHCDGRGGLKLSQDMDTC 277
Score = 102 bits (245), Expect = 2e-21
Identities = 53/125 (42%), Positives = 68/125 (54%), Gaps = 8/125 (6%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C IC N G F C C G+E S+G C+D+DEC D+ C RC+N GSY+
Sbjct: 164 NGG-CLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADS-EACGEARCKNLPGSYS 220
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCE--AGYRPTATRGACV 119
CLC+ GFA + C DVDEC C+ CVNS GS+ C C+ G + + C
Sbjct: 221 CLCDEGFAYSSQEKACRDVDEC-LQGRCE-QVCVNSPGSYTCHCDGRGGLKLSQDMDTCE 278
Query: 120 DVDEC 124
D+ C
Sbjct: 279 DILPC 283
Score = 91.9 bits (218), Expect = 4e-18
Identities = 51/147 (34%), Positives = 73/147 (49%), Gaps = 11/147 (7%)
Query: 20 ECICKPG--YESGSEGALCRD--VDECRDNPRVC-RRGR--CRNTAGSYTCLCEPGFAPT 72
+CI K G Y S A C D+C NP C R+G C++ G++ CLC+ G+
Sbjct: 94 DCINKYGSPYTKNSGFATCVQNLPDQCTPNP--CDRKGTQACQDLMGNFFCLCKAGWGGR 151
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
DV+EC+ ++ C N GSF C C +G+ ++ C D+DEC + C
Sbjct: 152 LCD--KDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGE 209
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTC 159
RC N PGS+ C C GF S+ + C
Sbjct: 210 ARCKNLPGSYSCLCDEGFAYSSQEKAC 236
Score = 82.6 bits (195), Expect = 3e-15
Identities = 43/127 (33%), Positives = 63/127 (49%), Gaps = 5/127 (3%)
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
QAC + LC G D+NEC+ G C C N + C C G+
Sbjct: 131 QACQDLMGNFFC-LCKAGWGGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFEL 188
Query: 231 DADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGET 288
+DG C+DIDEC ++ C +C+N GS++C+C EG + + + CRD+DEC +G
Sbjct: 189 SSDGRTCQDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRC 247
Query: 289 ETHYIES 295
E + S
Sbjct: 248 EQVCVNS 254
Score = 56.0 bits (129), Expect = 3e-07
Identities = 41/152 (26%), Positives = 62/152 (40%), Gaps = 23/152 (15%)
Query: 199 NECTAVPGACPHG---SCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQC 254
++CT P C +C++L + C+C G+ LC +D++EC C C
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW---GGRLCDKDVNECSQENGGCLQ-IC 171
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECE-----GETETHYIESDY----ERGDIPPT 305
N GSF C C G + + C+DIDEC GE + Y + G +
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSS 231
Query: 306 FPTRTELASPCDNGRC----INTHGGFECECE 333
C GRC +N+ G + C C+
Sbjct: 232 QEKACRDVDECLQGRCEQVCVNSPGSYTCHCD 263
Score = 47.2 bits (107), Expect = 1e-04
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
DG TC+D+DECA +E C C N GSY C C G S
Sbjct: 191 DGRTCQDIDECA-DSEACGEARCKNLPGSYSCLCDEGFAYSS 231
Score = 41.1 bits (92), Expect = 0.008
Identities = 36/118 (30%), Positives = 41/118 (34%), Gaps = 26/118 (22%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C N G F C C G+ L + + C D C G EA L C C G
Sbjct: 171 CHNKPGSFHCSCHSGFELSSDGRTCQDI--DECADSEACG--EARCKNLPGSYSCLCDEG 226
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A+ S CRDVDEC C CVN+ GSY C C
Sbjct: 227 FAYSSQEKA-------------------CRDVDECLQGR--CEQ-VCVNSPGSYTCHC 262
Score = 32.3 bits (70), Expect = 3.6
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 406 GATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C +DV+EC+ C C N GS+ C C G L S G
Sbjct: 150 GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDG 192
>BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific 6
protein.
Length = 678
Score = 114 bits (274), Expect = 7e-25
Identities = 61/152 (40%), Positives = 82/152 (53%), Gaps = 11/152 (7%)
Query: 12 CKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C+++ G F C+CK G+ G LC +DV+EC C + C N GS+ C C GF
Sbjct: 133 CQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFE 187
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
++ G C D+DECA C RC N GS+ C+C+ G+ ++ AC DVDEC + R
Sbjct: 188 LSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR- 246
Query: 130 CRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
C C N+PGS+ C C G LS D TC
Sbjct: 247 CEQ-VCVNSPGSYTCHCDGRGGLKLSQDMDTC 277
Score = 102 bits (245), Expect = 2e-21
Identities = 53/125 (42%), Positives = 68/125 (54%), Gaps = 8/125 (6%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C IC N G F C C G+E S+G C+D+DEC D+ C RC+N GSY+
Sbjct: 164 NGG-CLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADS-EACGEARCKNLPGSYS 220
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCE--AGYRPTATRGACV 119
CLC+ GFA + C DVDEC C+ CVNS GS+ C C+ G + + C
Sbjct: 221 CLCDEGFAYSSQEKACRDVDEC-LQGRCE-QVCVNSPGSYTCHCDGRGGLKLSQDMDTCE 278
Query: 120 DVDEC 124
D+ C
Sbjct: 279 DILPC 283
Score = 91.9 bits (218), Expect = 4e-18
Identities = 51/147 (34%), Positives = 73/147 (49%), Gaps = 11/147 (7%)
Query: 20 ECICKPG--YESGSEGALCRD--VDECRDNPRVC-RRGR--CRNTAGSYTCLCEPGFAPT 72
+CI K G Y S A C D+C NP C R+G C++ G++ CLC+ G+
Sbjct: 94 DCINKYGSPYTKNSGFATCVQNLPDQCTPNP--CDRKGTQACQDLMGNFFCLCKAGWGGR 151
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
DV+EC+ ++ C N GSF C C +G+ ++ C D+DEC + C
Sbjct: 152 LCD--KDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGE 209
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTC 159
RC N PGS+ C C GF S+ + C
Sbjct: 210 ARCKNLPGSYSCLCDEGFAYSSQEKAC 236
Score = 82.6 bits (195), Expect = 3e-15
Identities = 43/127 (33%), Positives = 63/127 (49%), Gaps = 5/127 (3%)
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
QAC + LC G D+NEC+ G C C N + C C G+
Sbjct: 131 QACQDLMGNFFC-LCKAGWGGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFEL 188
Query: 231 DADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGET 288
+DG C+DIDEC ++ C +C+N GS++C+C EG + + + CRD+DEC +G
Sbjct: 189 SSDGRTCQDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRC 247
Query: 289 ETHYIES 295
E + S
Sbjct: 248 EQVCVNS 254
Score = 56.0 bits (129), Expect = 3e-07
Identities = 41/152 (26%), Positives = 62/152 (40%), Gaps = 23/152 (15%)
Query: 199 NECTAVPGACPHG---SCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQC 254
++CT P C +C++L + C+C G+ LC +D++EC C C
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW---GGRLCDKDVNECSQENGGCLQ-IC 171
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECE-----GETETHYIESDY----ERGDIPPT 305
N GSF C C G + + C+DIDEC GE + Y + G +
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSS 231
Query: 306 FPTRTELASPCDNGRC----INTHGGFECECE 333
C GRC +N+ G + C C+
Sbjct: 232 QEKACRDVDECLQGRCEQVCVNSPGSYTCHCD 263
Score = 47.2 bits (107), Expect = 1e-04
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
DG TC+D+DECA +E C C N GSY C C G S
Sbjct: 191 DGRTCQDIDECA-DSEACGEARCKNLPGSYSCLCDEGFAYSS 231
Score = 41.1 bits (92), Expect = 0.008
Identities = 36/118 (30%), Positives = 41/118 (34%), Gaps = 26/118 (22%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C N G F C C G+ L + + C D C G EA L C C G
Sbjct: 171 CHNKPGSFHCSCHSGFELSSDGRTCQDI--DECADSEACG--EARCKNLPGSYSCLCDEG 226
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A+ S CRDVDEC C CVN+ GSY C C
Sbjct: 227 FAYSSQEKA-------------------CRDVDECLQGR--CEQ-VCVNSPGSYTCHC 262
Score = 32.3 bits (70), Expect = 3.6
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 406 GATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C +DV+EC+ C C N GS+ C C G L S G
Sbjct: 150 GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDG 192
>AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specific 6
protein.
Length = 678
Score = 114 bits (274), Expect = 7e-25
Identities = 61/152 (40%), Positives = 82/152 (53%), Gaps = 11/152 (7%)
Query: 12 CKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C+++ G F C+CK G+ G LC +DV+EC C + C N GS+ C C GF
Sbjct: 133 CQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFE 187
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
++ G C D+DECA C RC N GS+ C+C+ G+ ++ AC DVDEC + R
Sbjct: 188 LSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR- 246
Query: 130 CRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
C C N+PGS+ C C G LS D TC
Sbjct: 247 CEQ-VCVNSPGSYTCHCDGRGGLKLSQDMDTC 277
Score = 102 bits (245), Expect = 2e-21
Identities = 53/125 (42%), Positives = 68/125 (54%), Gaps = 8/125 (6%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C IC N G F C C G+E S+G C+D+DEC D+ C RC+N GSY+
Sbjct: 164 NGG-CLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADS-EACGEARCKNLPGSYS 220
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCE--AGYRPTATRGACV 119
CLC+ GFA + C DVDEC C+ CVNS GS+ C C+ G + + C
Sbjct: 221 CLCDEGFAYSSQEKACRDVDEC-LQGRCE-QVCVNSPGSYTCHCDGRGGLKLSQDMDTCE 278
Query: 120 DVDEC 124
D+ C
Sbjct: 279 DILPC 283
Score = 91.9 bits (218), Expect = 4e-18
Identities = 51/147 (34%), Positives = 73/147 (49%), Gaps = 11/147 (7%)
Query: 20 ECICKPG--YESGSEGALCRD--VDECRDNPRVC-RRGR--CRNTAGSYTCLCEPGFAPT 72
+CI K G Y S A C D+C NP C R+G C++ G++ CLC+ G+
Sbjct: 94 DCINKYGSPYTKNSGFATCVQNLPDQCTPNP--CDRKGTQACQDLMGNFFCLCKAGWGGR 151
Query: 73 AAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN 132
DV+EC+ ++ C N GSF C C +G+ ++ C D+DEC + C
Sbjct: 152 LCD--KDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGE 209
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTC 159
RC N PGS+ C C GF S+ + C
Sbjct: 210 ARCKNLPGSYSCLCDEGFAYSSQEKAC 236
Score = 82.6 bits (195), Expect = 3e-15
Identities = 43/127 (33%), Positives = 63/127 (49%), Gaps = 5/127 (3%)
Query: 171 QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
QAC + LC G D+NEC+ G C C N + C C G+
Sbjct: 131 QACQDLMGNFFC-LCKAGWGGRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFEL 188
Query: 231 DADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGET 288
+DG C+DIDEC ++ C +C+N GS++C+C EG + + + CRD+DEC +G
Sbjct: 189 SSDGRTCQDIDECADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRC 247
Query: 289 ETHYIES 295
E + S
Sbjct: 248 EQVCVNS 254
Score = 56.0 bits (129), Expect = 3e-07
Identities = 41/152 (26%), Positives = 62/152 (40%), Gaps = 23/152 (15%)
Query: 199 NECTAVPGACPHG---SCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQC 254
++CT P C +C++L + C+C G+ LC +D++EC C C
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW---GGRLCDKDVNECSQENGGCLQ-IC 171
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECE-----GETETHYIESDY----ERGDIPPT 305
N GSF C C G + + C+DIDEC GE + Y + G +
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSS 231
Query: 306 FPTRTELASPCDNGRC----INTHGGFECECE 333
C GRC +N+ G + C C+
Sbjct: 232 QEKACRDVDECLQGRCEQVCVNSPGSYTCHCD 263
Score = 47.2 bits (107), Expect = 1e-04
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
DG TC+D+DECA +E C C N GSY C C G S
Sbjct: 191 DGRTCQDIDECA-DSEACGEARCKNLPGSYSCLCDEGFAYSS 231
Score = 41.1 bits (92), Expect = 0.008
Identities = 36/118 (30%), Positives = 41/118 (34%), Gaps = 26/118 (22%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C N G F C C G+ L + + C D C G EA L C C G
Sbjct: 171 CHNKPGSFHCSCHSGFELSSDGRTCQDI--DECADSEACG--EARCKNLPGSYSCLCDEG 226
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A+ S CRDVDEC C CVN+ GSY C C
Sbjct: 227 FAYSSQEKA-------------------CRDVDECLQGR--CEQ-VCVNSPGSYTCHC 262
Score = 32.3 bits (70), Expect = 3.6
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 406 GATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C +DV+EC+ C C N GS+ C C G L S G
Sbjct: 150 GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDG 192
>AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens
cDNA FLJ44569 fis, clone UTERU3009979, highly similar
to Homo sapiens growth arrest-specific 6 (GAS6). ).
Length = 624
Score = 114 bits (274), Expect = 7e-25
Identities = 61/152 (40%), Positives = 82/152 (53%), Gaps = 11/152 (7%)
Query: 12 CKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C+++ G F C+CK G+ G LC +DV+EC C + C N GS+ C C GF
Sbjct: 79 CQDLMGNFFCLCKAGWG----GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFE 133
Query: 71 PTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
++ G C D+DECA C RC N GS+ C+C+ G+ ++ AC DVDEC + R
Sbjct: 134 LSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGR- 192
Query: 130 CRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
C C N+PGS+ C C G LS D TC
Sbjct: 193 CEQ-VCVNSPGSYTCHCDGRGGLKLSQDMDTC 223
Score = 102 bits (245), Expect = 2e-21
Identities = 53/125 (42%), Positives = 68/125 (54%), Gaps = 8/125 (6%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C IC N G F C C G+E S+G C+D+DEC D+ C RC+N GSY+
Sbjct: 110 NGG-CLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADS-EACGEARCKNLPGSYS 166
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCE--AGYRPTATRGACV 119
CLC+ GFA + C DVDEC C+ CVNS GS+ C C+ G + + C
Sbjct: 167 CLCDEGFAYSSQEKACRDVDEC-LQGRCE-QVCVNSPGSYTCHCDGRGGLKLSQDMDTCE 224
Query: 120 DVDEC 124
D+ C
Sbjct: 225 DILPC 229
Score = 91.1 bits (216), Expect = 7e-18
Identities = 51/146 (34%), Positives = 72/146 (49%), Gaps = 11/146 (7%)
Query: 21 CICKPG--YESGSEGALCRD--VDECRDNPRVC-RRGR--CRNTAGSYTCLCEPGFAPTA 73
CI K G Y S A C D+C NP C R+G C++ G++ CLC+ G+
Sbjct: 41 CINKYGSPYTKNSGFATCVQNLPDQCTPNP--CDRKGTQACQDLMGNFFCLCKAGWGGRL 98
Query: 74 AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNG 133
DV+EC+ ++ C N GSF C C +G+ ++ C D+DEC + C
Sbjct: 99 CD--KDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEA 156
Query: 134 RCHNTPGSFRCECLPGFTLSNDGRTC 159
RC N PGS+ C C GF S+ + C
Sbjct: 157 RCKNLPGSYSCLCDEGFAYSSQEKAC 182
Score = 83.4 bits (197), Expect = 1e-15
Identities = 66/235 (28%), Positives = 97/235 (41%), Gaps = 38/235 (16%)
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C+C+ P A C + C + GG +E C+ + G T G V
Sbjct: 2 CMCQASPPPAALAGCL-LSSCVQPAREHGGAFSKAEWLSNCINKYGSPYTKNSGFATCVQ 60
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
+Q C C + G+ C+ L G CL K GWG
Sbjct: 61 NLPDQ--CTPNPC-DRKGTQACQDLMGNFF------CL-CKAGWG--------------G 96
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDE 241
LC + D+NEC+ G C C N + C C G+ +DG C+DIDE
Sbjct: 97 RLCDK---------DVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDGRTCQDIDE 146
Query: 242 CDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC-EGETETHYIES 295
C ++ C +C+N GS++C+C EG + + + CRD+DEC +G E + S
Sbjct: 147 CADSEA-CGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRCEQVCVNS 200
Score = 56.0 bits (129), Expect = 3e-07
Identities = 41/152 (26%), Positives = 62/152 (40%), Gaps = 23/152 (15%)
Query: 199 NECTAVPGACPHG---SCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQC 254
++CT P C +C++L + C+C G+ LC +D++EC C C
Sbjct: 64 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW---GGRLCDKDVNECSQENGGCLQ-IC 117
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECE-----GETETHYIESDY----ERGDIPPT 305
N GSF C C G + + C+DIDEC GE + Y + G +
Sbjct: 118 HNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSS 177
Query: 306 FPTRTELASPCDNGRC----INTHGGFECECE 333
C GRC +N+ G + C C+
Sbjct: 178 QEKACRDVDECLQGRCEQVCVNSPGSYTCHCD 209
Score = 47.2 bits (107), Expect = 1e-04
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
DG TC+D+DECA +E C C N GSY C C G S
Sbjct: 137 DGRTCQDIDECA-DSEACGEARCKNLPGSYSCLCDEGFAYSS 177
Score = 41.1 bits (92), Expect = 0.008
Identities = 36/118 (30%), Positives = 41/118 (34%), Gaps = 26/118 (22%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C N G F C C G+ L + + C D C G EA L C C G
Sbjct: 117 CHNKPGSFHCSCHSGFELSSDGRTCQDI--DECADSEACG--EARCKNLPGSYSCLCDEG 172
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
A+ S CRDVDEC C CVN+ GSY C C
Sbjct: 173 FAYSSQEKA-------------------CRDVDECLQGR--CEQ-VCVNSPGSYTCHC 208
Score = 32.3 bits (70), Expect = 3.6
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 406 GATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
G C +DV+EC+ C C N GS+ C C G L S G
Sbjct: 96 GRLCDKDVNECSQENGGCLQ-ICHNKPGSFHCSCHSGFELSSDG 138
>AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens
cDNA FLJ34743 fis, clone MESAN2009019, moderately
similar to CEGP1 protein. ).
Length = 880
Score = 113 bits (271), Expect = 2e-24
Identities = 72/193 (37%), Positives = 92/193 (47%), Gaps = 15/193 (7%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
N G C + C + G C C G+ + C+D+DECR N C CRNT GS+
Sbjct: 130 NNGGCDSK-CHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH-ICRNTVGSFE 187
Query: 63 CLCEPGFAPTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C+ G+ C D+DEC+ D C CVN+ GSFQC+C GY C DV
Sbjct: 188 CSCKKGYKLLINERNCQDIDECSFDRTC-DHICVNTPGSFQCLCHRGYLLYGIT-HCGDV 245
Query: 122 DECEEQR-VCRNGRCHNTPGSFRCECLPG-FTLSNDGRTCLGLKLGWGVSCQACPAQGSE 179
DEC R CR G C NTPGS++C C G L +G+ C + CQ P G+
Sbjct: 246 DECSINRGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTE-----PLKCQGSP--GAS 297
Query: 180 LYAVLCPEGPSKD 192
+ C KD
Sbjct: 298 KAMLSCNRSGKKD 310
Score = 86.6 bits (205), Expect = 2e-16
Identities = 79/264 (29%), Positives = 105/264 (39%), Gaps = 54/264 (20%)
Query: 99 GSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR------CHNTP-GSFRCECLPGFT 151
GS++C C G+ + + C+ EE C N C TP G CEC PGF
Sbjct: 3 GSYECHCREGFFLSDNQHTCIQ--RPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFE 60
Query: 152 LSNDGRTC-LGLKLGWGVSCQAC------PAQGSELYAVLCPEGPSKDNGG--------- 195
L+ + R C L G G C P G + VL +G +
Sbjct: 61 LTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIGERRLEQHIPTQ 120
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQC 254
A NE AV C + G C C G+ D C+DIDEC ++ C C
Sbjct: 121 AVSNETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGC-DHIC 179
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
RNT GSF C C +G + + C+DIDEC ++R
Sbjct: 180 RNTVGSFECSCKKGYKLLINERNCQDIDEC-----------SFDR--------------- 213
Query: 315 PCDNGRCINTHGGFECECELGYVL 338
CD+ C+NT G F+C C GY+L
Sbjct: 214 TCDH-ICVNTPGSFQCLCHRGYLL 236
Score = 82.6 bits (195), Expect = 3e-15
Identities = 60/178 (33%), Positives = 76/178 (42%), Gaps = 16/178 (8%)
Query: 40 DECRDNPRVCRRGRCRNTAGSYTCLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSE 98
+ C N C +C + A C C GF C D+DEC ++ C N+
Sbjct: 125 ETCAVNNGGCD-SKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTV 183
Query: 99 GSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCEC-----LPGFTLS 153
GSF+C C+ GY+ C D+DEC R C + C NTPGSF+C C L G T
Sbjct: 184 GSFECSCKKGYKLLINERNCQDIDECSFDRTC-DHICVNTPGSFQCLCHRGYLLYGITHC 242
Query: 154 NDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDN-GGADINE---CTAVPGA 207
D C + G C P GS Y CP G + + G D E C PGA
Sbjct: 243 GDVDECSINRGGCRFGCINTP--GS--YQCTCPAGQGRLHWNGKDCTEPLKCQGSPGA 296
Score = 81.0 bits (191), Expect = 8e-15
Identities = 74/278 (26%), Positives = 105/278 (37%), Gaps = 33/278 (11%)
Query: 17 GGFECICKPGYESGSEGALCRDVDE----CRDNPRVCRRGRCRNTA-GSYTCLCEPGFAP 71
G +EC C+ G+ C E C + C CR T G C C PGF
Sbjct: 3 GSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH-ICRETPKGGIACECRPGFEL 61
Query: 72 TAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ---- 127
T + + C+ C ++E +C C + C+ E+
Sbjct: 62 TKNQRDCKLTCNYGNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTCIGERRLEQHIPTQ 120
Query: 128 ----RVC--RNG----RCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSCQACP 174
C NG +CH+ C C GF L D +TC + +L G C
Sbjct: 121 AVSNETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICR 180
Query: 175 -AQGSELYAVLCPEGPS---KDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHP 230
GS + C +G + DI+EC+ C H C N ++C+C GY
Sbjct: 181 NTVGS--FECSCKKGYKLLINERNCQDIDECS-FDRTCDH-ICVNTPGSFQCLCHRGYLL 236
Query: 231 DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C D+DEC +++ C G C NT GS+ C CP G
Sbjct: 237 YGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 273
Score = 76.6 bits (180), Expect = 2e-13
Identities = 59/234 (25%), Positives = 86/234 (36%), Gaps = 19/234 (8%)
Query: 11 ICKNID-GGFECICKPGYE------------SGSEGALCRDVDECRDNPRV-CRRGRCRN 56
IC+ GG C C+PG+E + G D+ PR C +
Sbjct: 42 ICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLH 101
Query: 57 TAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG 116
T G TC+ E + CA ++ +C ++ C C G+ R
Sbjct: 102 TDGK-TCIGERRLEQHIPTQAVSNETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRK 160
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL-KLGWGVSCQACPA 175
C D+DEC + C NT GSF C C G+ L + R C + + + +C
Sbjct: 161 TCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDHICV 220
Query: 176 QGSELYAVLCPEG--PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPG 227
+ LC G D++EC+ G C G C N Y+C C G
Sbjct: 221 NTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 273
Score = 73.7 bits (173), Expect = 1e-12
Identities = 90/327 (27%), Positives = 119/327 (36%), Gaps = 81/327 (24%)
Query: 140 GSFRCECLPGFTLSNDGRTCL-----GLKL-----GWGVSCQACPAQGSELYAVLCPEGP 189
GS+ C C GF LS++ TC+ G+ G C+ P G A C G
Sbjct: 3 GSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGG---IACECRPGF 59
Query: 190 SKDNGGADIN-ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMH-- 245
D C G C H +C++ E G RC C + DG C + H
Sbjct: 60 ELTKNQRDCKLTCNYGNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTCIGERRLEQHIP 118
Query: 246 -----QSYCA---GG---QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
CA GG +C + A C CP G +P+ + C+DID E
Sbjct: 119 TQAVSNETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDID-----------E 167
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCW 354
G CD+ C NT G FEC C+ GY L + C D S +
Sbjct: 168 CRLNNGG--------------CDH-ICRNTVGSFECSCKKGYKLLINERNCQDIDECS-F 211
Query: 355 RRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDE 414
R D C +C C +G+ C DVDE
Sbjct: 212 DRTCDHICVNTPGSF----QCLCH--------------------RGYLLYGITHCGDVDE 247
Query: 415 CALSAELCAGGTCVNTDGSYRCDCPPG 441
C+++ C G C+NT GSY+C CP G
Sbjct: 248 CSINRGGCRFG-CINTPGSYQCTCPAG 273
Score = 44.8 bits (101), Expect = 6e-04
Identities = 61/238 (25%), Positives = 92/238 (38%), Gaps = 41/238 (17%)
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE 267
C H E + G C C PG+ L ++ +C + +Y GG C++T T P
Sbjct: 39 CAHICRETPKGGIACECRPGFE-----LTKNQRDCKLTCNYGNGG-CQHTCDD-TEQGPR 91
Query: 268 GTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGG 327
H + L D C GE +E + + T CD+ +C + G
Sbjct: 92 CGCHI-KFVLHTDGKTCIGERR---LEQHIPTQAV--SNETCAVNNGGCDS-KCHDAATG 144
Query: 328 FECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXX 387
C C +G++L + C D C R+ +G C+ + EC C
Sbjct: 145 VHCTCPVGFMLQPDRKTCKDI--DEC--RLNNGGCDHICRNTVGSFECSCK--------- 191
Query: 388 XXXXXXXXXXXKGFAKL-DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
KG+ L + C+D+DEC S + CVNT GS++C C G L
Sbjct: 192 -----------KGYKLLINERNCQDIDEC--SFDRTCDHICVNTPGSFQCLCHRGYLL 236
>AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens
cDNA FLJ32009 fis, clone NT2RP7009498, weakly similar to
FIBULIN-1, ISOFORM A PRECURSOR. ).
Length = 955
Score = 113 bits (271), Expect = 2e-24
Identities = 63/159 (39%), Positives = 84/159 (52%), Gaps = 16/159 (10%)
Query: 7 CTNGICKNIDGGFECICKPGYE--SGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
C +G C+ + +C G+ + G C D+DEC + C G C NT G + C
Sbjct: 113 CNHGGCQEVAR----VCPVGFSMTEAAVGIRCTDIDECVTSS--CE-GHCVNTEGGFVCE 165
Query: 65 CEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PG +A + C D DEC + C+ RC NS GS++C C G+ R +CVDV+E
Sbjct: 166 CGPGMQLSADRHSCQDTDECLG-TPCQQ-RCKNSIGSYKCSCRTGFHLHGNRHSCVDVNE 223
Query: 124 CE---EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
C E+RVC + CHNT GSF C C PGF L D +C
Sbjct: 224 CRRPLERRVCHHS-CHNTVGSFLCTCRPGFRLRADRVSC 261
Score = 91.5 bits (217), Expect = 6e-18
Identities = 58/165 (35%), Positives = 79/165 (47%), Gaps = 16/165 (9%)
Query: 4 GGMCTNGICKNIDGGFECICKP--GYESGSEGALCRDVD-ECRDN--PRVCRRGRCRNTA 58
GG CT +C G CI + G +GA C + C + C G C+ A
Sbjct: 63 GGHCTLPLCSFGCGSGICIAPNVCSCQDGEQGATCPETHGPCGEYGCDLTCNHGGCQEVA 122
Query: 59 GSYTCLCEPGFAPTAAGY---CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATR 115
+C GF+ T A C D+DEC S C+G CVN+EG F C C G + +A R
Sbjct: 123 R----VCPVGFSMTEAAVGIRCTDIDECVTSS-CEG-HCVNTEGGFVCECGPGMQLSADR 176
Query: 116 GACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
+C D DEC C+ RC N+ GS++C C GF L + +C+
Sbjct: 177 HSCQDTDEC-LGTPCQQ-RCKNSIGSYKCSCRTGFHLHGNRHSCV 219
Score = 74.9 bits (176), Expect = 5e-13
Identities = 68/226 (30%), Positives = 79/226 (34%), Gaps = 26/226 (11%)
Query: 18 GFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG----FAPTA 73
GF C PG+ G C + C C G C C C+ G P
Sbjct: 48 GFGSGCCPGWAPSMGGGHCT-LPLCSFG---CGSGIC---IAPNVCSCQDGEQGATCPET 100
Query: 74 AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPT--ATRGACVDVDECEEQRVCR 131
G C E D C G C VC G+ T A C D+DEC C
Sbjct: 101 HGPCG---EYGCDLTCNHGGCQEVAR----VCPVGFSMTEAAVGIRCTDIDECVTSS-CE 152
Query: 132 NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG--- 188
G C NT G F CEC PG LS D +C G CQ Y C G
Sbjct: 153 -GHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTPCQQRCKNSIGSYKCSCRTGFHL 211
Query: 189 PSKDNGGADINEC-TAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ D+NEC + H SC N + C C PG+ AD
Sbjct: 212 HGNRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCRPGFRLRAD 257
Score = 63.3 bits (147), Expect = 2e-09
Identities = 63/204 (30%), Positives = 82/204 (40%), Gaps = 27/204 (13%)
Query: 94 CVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLS 153
C++ GS C G+ P+ G C + C C +G C P C C G
Sbjct: 45 CLSGFGSGCC---PGWAPSMGGGHCT-LPLCSFG--CGSGICI-APNV--CSCQDG---- 91
Query: 154 NDGRTCLGLKLGWG-VSCQ-ACPAQGSELYAVLCPEGPSKDNGGA-----DINECTAVPG 206
G TC G C C G + A +CP G S DI+EC V
Sbjct: 92 EQGATCPETHGPCGEYGCDLTCNHGGCQEVARVCPVGFSMTEAAVGIRCTDIDEC--VTS 149
Query: 207 ACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
+C G C N E G+ C C PG AD C+D DEC + C +C+N+ GS+ C C
Sbjct: 150 SC-EGHCVNTEGGFVCECGPGMQLSADRHSCQDTDEC--LGTPCQQ-RCKNSIGSYKCSC 205
Query: 266 PEGTRHEPELQLCRDIDECEGETE 289
G C D++EC E
Sbjct: 206 RTGFHLHGNRHSCVDVNECRRPLE 229
Score = 58.4 bits (135), Expect = 5e-08
Identities = 63/241 (26%), Positives = 90/241 (37%), Gaps = 33/241 (13%)
Query: 55 RNTAGSYTCL------CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG 108
R G + CL C PG+AP+ G + C+ C G C+ C C+ G
Sbjct: 37 RRRLGPHVCLSGFGSGCCPGWAPSMGGGHCTLPLCSFG--CGSGICIAPN---VCSCQDG 91
Query: 109 YRPTA---TRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSND--GRTCLGLK 163
+ T G C + C+ C +G C C GF+++ G C +
Sbjct: 92 EQGATCPETHGPCGEYG-CD--LTCNHGGCQEVARV----CPVGFSMTEAAVGIRCTDID 144
Query: 164 LGWGVSCQACPAQGSELYAVLCPEGP--SKDNGGA-DINECTAVPGACPHGSCENLEPGY 220
SC+ + C G S D D +EC P C C+N Y
Sbjct: 145 ECVTSSCEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTP--CQQ-RCKNSIGSY 201
Query: 221 RCICDPGYHPDADG-LCRDIDEC--DMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQL 277
+C C G+H + C D++EC + + C C NT GSF C C G R +
Sbjct: 202 KCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHHS-CHNTVGSFLCTCRPGFRLRADRVS 260
Query: 278 C 278
C
Sbjct: 261 C 261
Score = 57.2 bits (132), Expect = 1e-07
Identities = 52/162 (32%), Positives = 65/162 (40%), Gaps = 28/162 (17%)
Query: 136 HNTPGSFRCECLPGFTLSNDGRTC------LGLKLGWGVSCQACPAQGSELYAVLCPE-- 187
H F C PG+ S G C G G ++ C Q E A CPE
Sbjct: 43 HVCLSGFGSGCCPGWAPSMGGGHCTLPLCSFGCGSGICIAPNVCSCQDGEQGAT-CPETH 101
Query: 188 GPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPD--ADGL-CRDIDECDM 244
GP + G D+ C HG C+ + +C G+ A G+ C DIDEC
Sbjct: 102 GPCGEYG-CDLT--------CNHGGCQEVAR----VCPVGFSMTEAAVGIRCTDIDECVT 148
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG 286
S C G C NT G F C C G + + C+D DEC G
Sbjct: 149 --SSCEG-HCVNTEGGFVCECGPGMQLSADRHSCQDTDECLG 187
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/135 (28%), Positives = 52/135 (38%), Gaps = 29/135 (21%)
Query: 312 LASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLL 371
+ S C+ G C+NT GGF CEC G L A C D C + C+ +
Sbjct: 147 VTSSCE-GHCVNTEGGFVCECGPGMQLSADRHSCQDT--DEC----LGTPCQQRCKNSIG 199
Query: 372 RQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDEC--ALSAELCAGGTCVN 429
+C C G + +C DV+EC L +C +C N
Sbjct: 200 SYKCSCRTGFHLHG-------------------NRHSCVDVNECRRPLERRVC-HHSCHN 239
Query: 430 TDGSYRCDCPPGLTL 444
T GS+ C C PG L
Sbjct: 240 TVGSFLCTCRPGFRL 254
Score = 45.2 bits (102), Expect = 5e-04
Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 3/41 (7%)
Query: 406 GATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDS 446
G C D+DEC S+ C G CVNT+G + C+C PG+ L +
Sbjct: 137 GIRCTDIDECVTSS--CEGH-CVNTEGGFVCECGPGMQLSA 174
>AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein.
Length = 451
Score = 112 bits (270), Expect = 2e-24
Identities = 65/195 (33%), Positives = 85/195 (43%), Gaps = 5/195 (2%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAP 71
C NI G + C CK GY S+ CR D C C + C N GS+ C C G+A
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 72 TAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
G C VD CA+++ CVN++GS+ C C G+ + C +D C
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG 371
Query: 131 RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGW--GVSCQACPAQGSELYAVLCPEG 188
C NT S+ C CL GFTL+ D +TC + C+ E Y C G
Sbjct: 372 CQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRG 431
Query: 189 PSKD-NGGADINECT 202
+ D NG ECT
Sbjct: 432 YTLDPNGKTCSRECT 446
Score = 98.3 bits (234), Expect = 5e-20
Identities = 51/161 (31%), Positives = 70/161 (43%), Gaps = 3/161 (1%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+C N+ G F C C GY +G C VD C C C N GSY C C GFA
Sbjct: 293 LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFA 351
Query: 71 PTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
C +D CA+ + CVN++ S+ C C G+ + C ++ C +
Sbjct: 352 LNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKP 411
Query: 130 CRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSC 170
C N S+ C C G+TL +G+TC + GV C
Sbjct: 412 GCEHECVNMEESYYCRCHRGYTLDPNGKTC-SRECTLGVGC 451
Score = 93.9 bits (223), Expect = 1e-18
Identities = 61/188 (32%), Positives = 77/188 (40%), Gaps = 9/188 (4%)
Query: 54 CRNTAGSYTCLCEPGFAPTA-AGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPT 112
C N GSY C C+ G+ + C D CA + CVN GSF C C +GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 113 ATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKL--GWGVSC 170
CV VD C + C N GS+ C+C GF L+ D +TC + C
Sbjct: 313 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGC 372
Query: 171 QACPAQGSELYAVLCPEG----PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDP 226
Q + Y+ C +G P K IN C C H C N+E Y C C
Sbjct: 373 QHECVNTDDSYSCHCLKGFTLNPDKKTCRR-INYCALNKPGCEH-ECVNMEESYYCRCHR 430
Query: 227 GYHPDADG 234
GY D +G
Sbjct: 431 GYTLDPNG 438
Score = 89.0 bits (211), Expect = 3e-17
Identities = 60/195 (30%), Positives = 85/195 (43%), Gaps = 16/195 (8%)
Query: 94 CVNSEGSFQCVCEAGYRPTATRGACVDVDECE-EQRVCRNGRCHNTPGSFRCECLPGFTL 152
C+N GS+ C C+ GY + + C D C E C C N PGSF C+C G+ L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 153 SNDGRTCLGLKL----GWGVSCQACPAQGSELYAVLCPEG----PSKDNGGADINECTAV 204
+ DG+ C+ + G + A GS Y C EG P K I+ C +
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGS--YLCQCHEGFALNPDKKTC-TKIDYCASS 368
Query: 205 PGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTC 263
C H C N + Y C C G+ + D CR I+ C +++ C +C N S+ C
Sbjct: 369 NHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYC 426
Query: 264 VCPEGTRHEPELQLC 278
C G +P + C
Sbjct: 427 RCHRGYTLDPNGKTC 441
Score = 68.1 bits (159), Expect = 6e-11
Identities = 55/217 (25%), Positives = 79/217 (36%), Gaps = 34/217 (15%)
Query: 135 CHNTPGSFRCECLPGFTLSNDGRTCL--GLKLGWGVSCQACPAQGSELYAVLCPEGPSKD 192
C N PGS+ C C G+ L++D TC L +C+ + C G +
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 193 NGG---ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSY 248
G ++ C + C H C N + Y C C G+ + D C ID C
Sbjct: 313 EDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG 371
Query: 249 CAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPT 308
C +C NT S++C C +G P+ + CR I+ C
Sbjct: 372 CQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYC------------------------ 406
Query: 309 RTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
L P C+N + C C GY LD + C
Sbjct: 407 --ALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTC 441
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/161 (27%), Positives = 66/161 (40%), Gaps = 18/161 (11%)
Query: 201 CTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-CRDIDECDMHQSYCAGGQCRNTAG 259
C+ + C H C N+ Y C C GY ++D CR D C M C C N G
Sbjct: 242 CSTLEHNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPG 299
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGET---ETHYIESD-------YERGDIPPTFPTR 309
SF C C G + + C +D C E E + +D +E + P T
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTC 359
Query: 310 TEL--ASPCDNG---RCINTHGGFECECELGYVLDATAQRC 345
T++ + ++G C+NT + C C G+ L+ + C
Sbjct: 360 TKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTC 400
Score = 48.4 bits (110), Expect = 5e-05
Identities = 38/125 (30%), Positives = 47/125 (37%), Gaps = 24/125 (19%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C+N G F C+C GY L +RC+ + + +C A L C C G
Sbjct: 294 CVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYL----CQCHEG 349
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPP 440
A D TC +D CA S C CVNTD SY C C
Sbjct: 350 FALNP-------------------DKKTCTKIDYCASSNHGCQH-ECVNTDDSYSCHCLK 389
Query: 441 GLTLD 445
G TL+
Sbjct: 390 GFTLN 394
Score = 35.9 bits (79), Expect = 0.29
Identities = 18/44 (40%), Positives = 20/44 (45%), Gaps = 1/44 (2%)
Query: 405 DGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTG 448
D TCR D CA+ C CVN GS+ C C G L G
Sbjct: 273 DQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYALAEDG 315
>AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein.
Length = 969
Score = 111 bits (266), Expect = 6e-24
Identities = 45/108 (41%), Positives = 64/108 (59%), Gaps = 6/108 (5%)
Query: 6 MCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCR-RGRCRNTAGSYTCL 64
+C G C N+ G+ C+C PGY+ A C D +EC +P C+ +GRC N GSY+C
Sbjct: 855 VCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CKGKGRCINRVGSYSCF 912
Query: 65 CEPGFAPTAAGY---CADVDECAADSMCKGGRCVNSEGSFQCVCEAGY 109
C PG+ +G C D++EC +C GG+C N+EGS+ C C+ GY
Sbjct: 913 CYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGY 960
Score = 108 bits (259), Expect = 5e-23
Identities = 55/125 (44%), Positives = 69/125 (55%), Gaps = 10/125 (8%)
Query: 39 VDECRDNP-RVCRRGRCRNTAGSYTCLCEPGFA--PTAAGYCADVDECAADSMCKG-GRC 94
+D C VC G C N Y C+C PG+ P+ A YC D +EC D CKG GRC
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQA-YCTDDNECLRDP-CKGKGRC 902
Query: 95 VNSEGSFQCVCEAGYRPTATRGA---CVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT 151
+N GS+ C C GY AT GA C D++ECE+ VC G+C NT GS+ CEC G+
Sbjct: 903 INRVGSYSCFCYPGYT-LATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYI 961
Query: 152 LSNDG 156
+ G
Sbjct: 962 MVRKG 966
Score = 75.8 bits (178), Expect = 3e-13
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 4/134 (2%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ +C D++EC +CK CVN+ GS+ C C G +R CV
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS---- 663
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVL 184
++ G C+ + G C ++ C + WG C+ CP G+E + +
Sbjct: 664 DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREI 723
Query: 185 CPEGPSKDNGGADI 198
CP G +DI
Sbjct: 724 CPAGHGYTYASSDI 737
Score = 72.5 bits (170), Expect = 3e-12
Identities = 32/81 (39%), Positives = 44/81 (54%), Gaps = 2/81 (2%)
Query: 80 VDECAADS--MCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHN 137
+D CAA + +C G CVN ++CVC GY+ ++ C D +EC GRC N
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 904
Query: 138 TPGSFRCECLPGFTLSNDGRT 158
GS+ C C PG+TL+ G T
Sbjct: 905 RVGSYSCFCYPGYTLATSGAT 925
Score = 70.9 bits (166), Expect = 8e-12
Identities = 39/94 (41%), Positives = 50/94 (53%), Gaps = 9/94 (9%)
Query: 198 INECTA-VPGACPHGSCENLEPGYRCICDPGY--HPDADGLCRDIDECDMHQSYCAG-GQ 253
I+ C A C G+C NL GYRC+C PGY HP + C D +EC + C G G+
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHP-SQAYCTDDNEC--LRDPCKGKGR 901
Query: 254 CRNTAGSFTCVCPEG--TRHEPELQLCRDIDECE 285
C N GS++C C G Q C+DI+ECE
Sbjct: 902 CINRVGSYSCFCYPGYTLATSGATQECQDINECE 935
Score = 70.5 bits (165), Expect = 1e-11
Identities = 38/105 (36%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 351 GSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWG----------SXXXXXXXXXXXXXKG 400
G C+ V+GQC EL +++CC SVG WG +G
Sbjct: 552 GRCYLNTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQG 611
Query: 401 FAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
+ +L+ C+D++EC L+ LC CVNT GSY C C PGL LD
Sbjct: 612 YKRLNLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLD 655
Score = 70.5 bits (165), Expect = 1e-11
Identities = 30/70 (42%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 10 GICKNIDGGFECICKPGYESGSEGAL--CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEP 67
G C N G + C C PGY + GA C+D++EC + P VC G+C NT GSY C C+
Sbjct: 900 GRCINRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQ 958
Query: 68 GFAPTAAGYC 77
G+ G+C
Sbjct: 959 GYIMVRKGHC 968
Score = 64.5 bits (150), Expect = 7e-10
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 6/76 (7%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNR-----RGSCWRRVVDGQCEAAAPELL 370
C + C+NT G + C C G +LD + RC+ ++ +G C+R + G C + +
Sbjct: 632 CKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRI 691
Query: 371 LRQECCCS-VGLAWGS 385
+Q CCCS VG AWGS
Sbjct: 692 TKQICCCSRVGKAWGS 707
Score = 63.7 bits (148), Expect = 1e-09
Identities = 49/136 (36%), Positives = 62/136 (45%), Gaps = 21/136 (15%)
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA 196
+TPG RC G T TC+ L G+ C + G +L+ PS+
Sbjct: 841 STPGIDRCAA--GATNVCGPGTCVNLPDGYRCVC----SPGYQLH-------PSQAYC-T 886
Query: 197 DINECTAVPGACP-HGSCENLEPGYRCICDPGYHPDADGL---CRDIDECDMHQSYCAGG 252
D NEC P C G C N Y C C PGY G C+DI+EC+ C+GG
Sbjct: 887 DDNECLRDP--CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQ-PGVCSGG 943
Query: 253 QCRNTAGSFTCVCPEG 268
QC NT GS+ C C +G
Sbjct: 944 QCTNTEGSYHCECDQG 959
Score = 62.5 bits (145), Expect = 3e-09
Identities = 41/126 (32%), Positives = 50/126 (39%), Gaps = 10/126 (7%)
Query: 121 VDECEE--QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS 178
+D C VC G C N P +RC C PG+ L C C+ +
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 904
Query: 179 EL--YAVLCPEGPSKDNGGA-----DINECTAVPGACPHGSCENLEPGYRCICDPGYHPD 231
+ Y+ C G + GA DINEC PG C G C N E Y C CD GY
Sbjct: 905 RVGSYSCFCYPGYTLATSGATQECQDINECEQ-PGVCSGGQCTNTEGSYHCECDQGYIMV 963
Query: 232 ADGLCR 237
G C+
Sbjct: 964 RKGHCQ 969
Score = 54.0 bits (124), Expect = 1e-06
Identities = 38/135 (28%), Positives = 53/135 (39%), Gaps = 26/135 (19%)
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C G C+N G+ C C GY L + C D+ C R G+ + C
Sbjct: 856 CGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNE--CLRDPCKGKGRCI--NRVGSYSC 911
Query: 376 CCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGAT--CRDVDECALSAELCAGGTCVNTDGS 433
C G + GAT C+D++EC +C+GG C NT+GS
Sbjct: 912 FCYPGYTLATS-------------------GATQECQDINECEQPG-VCSGGQCTNTEGS 951
Query: 434 YRCDCPPGLTLDSTG 448
Y C+C G + G
Sbjct: 952 YHCECDQGYIMVRKG 966
Score = 51.6 bits (118), Expect = 6e-06
Identities = 45/162 (27%), Positives = 63/162 (38%), Gaps = 15/162 (9%)
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQACPAQGS----ELYAVLCPE 187
GRC+ + +C P L+ C + WGV+ C CP + + E + CP+
Sbjct: 552 GRCYLNTVNGQC-ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQ 610
Query: 188 GPSKDN--GGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPD-ADGLCRDIDECDM 244
G + N DINEC + G C C N Y C C PG D + C M
Sbjct: 611 GYKRLNLTHCQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISM 669
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEG 286
Q G C + G TC P R ++ C + + G
Sbjct: 670 LQ-----GLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWG 706
Score = 41.5 bits (93), Expect = 0.006
Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 13/98 (13%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA--PTAAGYCADVDECAADSMCKGGR 93
C+D++EC +C+ C NT GSY C C PG P+ + +D A SM + G
Sbjct: 620 CQDINECL-TLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD----KAISMLQ-GL 673
Query: 94 CVNSEGSFQCVCEAGYRPTATRGACVDV-----DECEE 126
C S G C R T C V ECE+
Sbjct: 674 CYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEK 711
Score = 40.3 bits (90), Expect = 0.014
Identities = 17/34 (50%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 412 VDECALSA-ELCAGGTCVNTDGSYRCDCPPGLTL 444
+D CA A +C GTCVN YRC C PG L
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQL 878
Score = 33.9 bits (74), Expect = 1.2
Identities = 17/39 (43%), Positives = 18/39 (46%), Gaps = 3/39 (7%)
Query: 312 LASPCDN-GRCINTHGGFECECELGYVL--DATAQRCLD 347
L PC GRCIN G + C C GY L Q C D
Sbjct: 892 LRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQD 930
Score = 32.3 bits (70), Expect = 3.6
Identities = 10/23 (43%), Positives = 14/23 (60%)
Query: 5 GMCTNGICKNIDGGFECICKPGY 27
G+C+ G C N +G + C C GY
Sbjct: 938 GVCSGGQCTNTEGSYHCECDQGY 960
>BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein.
Length = 347
Score = 110 bits (264), Expect = 1e-23
Identities = 76/234 (32%), Positives = 102/234 (43%), Gaps = 22/234 (9%)
Query: 29 SGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVDECAADS 87
SG G++ DVDEC + C C+NT SY CLC+PG+ C D+DEC D
Sbjct: 26 SGLPGSV--DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGK-QCEDIDECENDY 82
Query: 88 MCKG--GRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCE 145
G C+N G+++C C G+ C+DVDEC++ C N GS+ C+
Sbjct: 83 YNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQ 142
Query: 146 CLPGFTL----------SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG 195
C GF L SN+G C+ G C+ P G A C G
Sbjct: 143 CHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGG---VACDCRPGFDLAQNQ 199
Query: 196 ADIN-ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQS 247
D C G C H SCE+ + G C C Y +DG C + DE + +S
Sbjct: 200 KDCTLTCNYGNGGCQH-SCEDTDTGPTCGCHQKYALHSDGRTCIEKDEAAIERS 252
Score = 98.7 bits (235), Expect = 4e-20
Identities = 55/161 (34%), Positives = 80/161 (49%), Gaps = 15/161 (9%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDN--PRVCRRGRCRNTAGSYTCLCE 66
+ IC+N ++C+CKPGY+ EG C D+DEC ++ C C N G+Y C C
Sbjct: 47 DAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH-ECINIPGNYRCTCF 103
Query: 67 PGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF G+ C DVDEC ++ CVN+ GS++C C +G+ + + C +
Sbjct: 104 DGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTC--IHRSN 161
Query: 126 EQRVCRNGR------CHNTP-GSFRCECLPGFTLSNDGRTC 159
E C N C TP G C+C PGF L+ + + C
Sbjct: 162 EGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC 202
Score = 73.7 bits (173), Expect = 1e-12
Identities = 78/289 (26%), Positives = 112/289 (38%), Gaps = 45/289 (15%)
Query: 194 GGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGG 252
G D++EC+ C + C+N Y+C+C PGY + C DIDEC+ Y GG
Sbjct: 30 GSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQ-CEDIDECE--NDYYNGG 86
Query: 253 ---QCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE--------------GETETHYIES 295
+C N G++ C C +G + C D+DEC+ G E S
Sbjct: 87 CVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQ-CHS 145
Query: 296 DYERGDIPPTFPTRTELASPC---DNG---RCINT-HGGFECECELGYVLDATAQRCLDN 348
+ D T R+ C D+G C T GG C+C G+ L + C
Sbjct: 146 GFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC--- 202
Query: 349 RRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGAT 408
+C +G C+ + + C C A S + ++ + +
Sbjct: 203 -TLTC--NYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIEKDEAAIER-SQFNATS 258
Query: 409 CRDVDECA---LSAELCA---GG---TCVNTDGSYRCDCPPGLTLDSTG 448
DVD+ L E CA GG TC +T RC CP G TL G
Sbjct: 259 VADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDG 307
Score = 46.4 bits (105), Expect = 2e-04
Identities = 44/169 (26%), Positives = 60/169 (35%), Gaps = 19/169 (11%)
Query: 11 ICKNID-GGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
IC+ GG C C+PG++ C C C+ C +T TC C +
Sbjct: 176 ICRETPKGGVACDCRPGFDLAQNQKDCTLT--CNYGNGGCQHS-CEDTDTGPTCGCHQKY 232
Query: 70 APTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQR 128
A + G C + DE A + F A R ++ C
Sbjct: 233 ALHSDGRTCIEKDEAAIE-----------RSQFNATSVADVDKRVKRRLLMET--CAVNN 279
Query: 129 VCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLG-WGVSCQACPAQ 176
+ C +T RC C GFTL DG+TC G + G C P Q
Sbjct: 280 GGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKGQHVELCGCPCLYWPGQ 328
>Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein.
Length = 676
Score = 106 bits (255), Expect = 1e-22
Identities = 60/156 (38%), Positives = 80/156 (51%), Gaps = 15/156 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRV---CRRGRCRNTAGSYTCLCEP 67
CK+ F C CKPG++ G C D++EC+D + C + C NT GSY C C+
Sbjct: 134 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKN 188
Query: 68 GFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + C DVDEC+ S+C C N G F+C C GYR +C D+DEC
Sbjct: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS 248
Query: 126 EQRVCRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
E +C C N PG + C C GF L+ D ++C
Sbjct: 249 E-NMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 85.8 bits (203), Expect = 3e-16
Identities = 44/125 (35%), Positives = 63/125 (50%), Gaps = 7/125 (5%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C+ IC N G + C CK G+ S C+DVDEC P +C C+N G +
Sbjct: 168 NGG-CSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFE 225
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEA--GYRPTATRGACV 119
C C G+ + C D+DEC +++MC CVN G + C C+ G++ + +C
Sbjct: 226 CECPEGYRYNLKSKSCEDIDEC-SENMC-AQLCVNYPGGYTCYCDGKKGFKLAQDQKSCE 283
Query: 120 DVDEC 124
V C
Sbjct: 284 VVSVC 288
Score = 80.2 bits (189), Expect = 1e-14
Identities = 39/112 (34%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
Query: 177 GSELYAVLCPEGPSKDNGGADINEC---TAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
G + C G + DINEC + + G C C+N Y C C G+ ++
Sbjct: 137 GKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSN 195
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C+D+DEC + S C C+N G F C CPEG R+ + + C DIDEC
Sbjct: 196 KKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC 247
Score = 51.6 bits (118), Expect = 6e-06
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 32/153 (20%)
Query: 199 NECTAVP-GACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCAGGQ--C 254
++C+ +P + SC++ + + C C PG+ + C DI+EC + G C
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK---CEFDINECKDPSNINGGCSQIC 175
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NT GS+ C C G + C+D+DEC + P S
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDEC----------------SLKP---------S 210
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLD 347
C C N G FECEC GY + ++ C D
Sbjct: 211 ICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
Score = 47.6 bits (108), Expect = 9e-05
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 400 GFAKLDGAT-CRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF L C+DVDEC+L +C C N G + C+CP G
Sbjct: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
Score = 36.3 bits (80), Expect = 0.22
Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 25/118 (21%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C NT G + C C+ G+V+ + + C D S + A + EC C G
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNIPGDFECECPEG 231
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
+ L +C D+DEC S +CA CVN G Y C C
Sbjct: 232 YRYN-------------------LKSKSCEDIDEC--SENMCAQ-LCVNYPGGYTCYC 267
Score = 31.1 bits (67), Expect = 8.4
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 406 GATCR-DVDECALSAELCAGGT--CVNTDGSYRCDCPPGLTL 444
G C D++EC + + G + C NT GSY C C G +
Sbjct: 151 GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 192
>M57853-1|AAA60357.1| 676|Homo sapiens S protein protein.
Length = 676
Score = 106 bits (255), Expect = 1e-22
Identities = 60/156 (38%), Positives = 80/156 (51%), Gaps = 15/156 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRV---CRRGRCRNTAGSYTCLCEP 67
CK+ F C CKPG++ G C D++EC+D + C + C NT GSY C C+
Sbjct: 134 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKN 188
Query: 68 GFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + C DVDEC+ S+C C N G F+C C GYR +C D+DEC
Sbjct: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS 248
Query: 126 EQRVCRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
E +C C N PG + C C GF L+ D ++C
Sbjct: 249 E-NMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 85.8 bits (203), Expect = 3e-16
Identities = 44/125 (35%), Positives = 63/125 (50%), Gaps = 7/125 (5%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C+ IC N G + C CK G+ S C+DVDEC P +C C+N G +
Sbjct: 168 NGG-CSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFE 225
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEA--GYRPTATRGACV 119
C C G+ + C D+DEC +++MC CVN G + C C+ G++ + +C
Sbjct: 226 CECPEGYRYNLKSKSCEDIDEC-SENMC-AQLCVNYPGGYTCYCDGKKGFKLAQDQKSCE 283
Query: 120 DVDEC 124
V C
Sbjct: 284 VVSVC 288
Score = 80.2 bits (189), Expect = 1e-14
Identities = 39/112 (34%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
Query: 177 GSELYAVLCPEGPSKDNGGADINEC---TAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
G + C G + DINEC + + G C C+N Y C C G+ ++
Sbjct: 137 GKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSN 195
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C+D+DEC + S C C+N G F C CPEG R+ + + C DIDEC
Sbjct: 196 KKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC 247
Score = 51.6 bits (118), Expect = 6e-06
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 32/153 (20%)
Query: 199 NECTAVP-GACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCAGGQ--C 254
++C+ +P + SC++ + + C C PG+ + C DI+EC + G C
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK---CEFDINECKDPSNINGGCSQIC 175
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NT GS+ C C G + C+D+DEC + P S
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDEC----------------SLKP---------S 210
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLD 347
C C N G FECEC GY + ++ C D
Sbjct: 211 ICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
Score = 47.6 bits (108), Expect = 9e-05
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 400 GFAKLDGAT-CRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF L C+DVDEC+L +C C N G + C+CP G
Sbjct: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
Score = 36.3 bits (80), Expect = 0.22
Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 25/118 (21%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C NT G + C C+ G+V+ + + C D S + A + EC C G
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNIPGDFECECPEG 231
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
+ L +C D+DEC S +CA CVN G Y C C
Sbjct: 232 YRYN-------------------LKSKSCEDIDEC--SENMCAQ-LCVNYPGGYTCYC 267
Score = 31.1 bits (67), Expect = 8.4
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 406 GATCR-DVDECALSAELCAGGT--CVNTDGSYRCDCPPGLTL 444
G C D++EC + + G + C NT GSY C C G +
Sbjct: 151 GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 192
>M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein.
Length = 650
Score = 106 bits (255), Expect = 1e-22
Identities = 60/156 (38%), Positives = 80/156 (51%), Gaps = 15/156 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRV---CRRGRCRNTAGSYTCLCEP 67
CK+ F C CKPG++ G C D++EC+D + C + C NT GSY C C+
Sbjct: 108 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKN 162
Query: 68 GFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + C DVDEC+ S+C C N G F+C C GYR +C D+DEC
Sbjct: 163 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS 222
Query: 126 EQRVCRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
E +C C N PG + C C GF L+ D ++C
Sbjct: 223 E-NMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 256
Score = 85.8 bits (203), Expect = 3e-16
Identities = 44/125 (35%), Positives = 63/125 (50%), Gaps = 7/125 (5%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C+ IC N G + C CK G+ S C+DVDEC P +C C+N G +
Sbjct: 142 NGG-CSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFE 199
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEA--GYRPTATRGACV 119
C C G+ + C D+DEC +++MC CVN G + C C+ G++ + +C
Sbjct: 200 CECPEGYRYNLKSKSCEDIDEC-SENMC-AQLCVNYPGGYTCYCDGKKGFKLAQDQKSCE 257
Query: 120 DVDEC 124
V C
Sbjct: 258 VVSVC 262
Score = 80.2 bits (189), Expect = 1e-14
Identities = 39/112 (34%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
Query: 177 GSELYAVLCPEGPSKDNGGADINEC---TAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
G + C G + DINEC + + G C C+N Y C C G+ ++
Sbjct: 111 GKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSN 169
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C+D+DEC + S C C+N G F C CPEG R+ + + C DIDEC
Sbjct: 170 KKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC 221
Score = 51.6 bits (118), Expect = 6e-06
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 32/153 (20%)
Query: 199 NECTAVP-GACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCAGGQ--C 254
++C+ +P + SC++ + + C C PG+ + C DI+EC + G C
Sbjct: 93 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK---CEFDINECKDPSNINGGCSQIC 149
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NT GS+ C C G + C+D+DEC + P S
Sbjct: 150 DNTPGSYHCSCKNGFVMLSNKKDCKDVDEC----------------SLKP---------S 184
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLD 347
C C N G FECEC GY + ++ C D
Sbjct: 185 ICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 217
Score = 47.6 bits (108), Expect = 9e-05
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 400 GFAKLDGAT-CRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF L C+DVDEC+L +C C N G + C+CP G
Sbjct: 163 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 205
Score = 36.3 bits (80), Expect = 0.22
Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 25/118 (21%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C NT G + C C+ G+V+ + + C D S + A + EC C G
Sbjct: 149 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNIPGDFECECPEG 205
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
+ L +C D+DEC S +CA CVN G Y C C
Sbjct: 206 YRYN-------------------LKSKSCEDIDEC--SENMCAQ-LCVNYPGGYTCYC 241
Score = 31.1 bits (67), Expect = 8.4
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 406 GATCR-DVDECALSAELCAGGT--CVNTDGSYRCDCPPGLTL 444
G C D++EC + + G + C NT GSY C C G +
Sbjct: 125 GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 166
>M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin
K-dependent plasma protein S mRNA, complete cds. ).
Length = 676
Score = 106 bits (255), Expect = 1e-22
Identities = 60/156 (38%), Positives = 80/156 (51%), Gaps = 15/156 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRV---CRRGRCRNTAGSYTCLCEP 67
CK+ F C CKPG++ G C D++EC+D + C + C NT GSY C C+
Sbjct: 134 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKN 188
Query: 68 GFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + C DVDEC+ S+C C N G F+C C GYR +C D+DEC
Sbjct: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS 248
Query: 126 EQRVCRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
E +C C N PG + C C GF L+ D ++C
Sbjct: 249 E-NMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 85.8 bits (203), Expect = 3e-16
Identities = 44/125 (35%), Positives = 63/125 (50%), Gaps = 7/125 (5%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C+ IC N G + C CK G+ S C+DVDEC P +C C+N G +
Sbjct: 168 NGG-CSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFE 225
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEA--GYRPTATRGACV 119
C C G+ + C D+DEC +++MC CVN G + C C+ G++ + +C
Sbjct: 226 CECPEGYRYNLKSKSCEDIDEC-SENMC-AQLCVNYPGGYTCYCDGKKGFKLAQDQKSCE 283
Query: 120 DVDEC 124
V C
Sbjct: 284 VVSVC 288
Score = 80.2 bits (189), Expect = 1e-14
Identities = 39/112 (34%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
Query: 177 GSELYAVLCPEGPSKDNGGADINEC---TAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
G + C G + DINEC + + G C C+N Y C C G+ ++
Sbjct: 137 GKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSN 195
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C+D+DEC + S C C+N G F C CPEG R+ + + C DIDEC
Sbjct: 196 KKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC 247
Score = 51.6 bits (118), Expect = 6e-06
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 32/153 (20%)
Query: 199 NECTAVP-GACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCAGGQ--C 254
++C+ +P + SC++ + + C C PG+ + C DI+EC + G C
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK---CEFDINECKDPSNINGGCSQIC 175
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NT GS+ C C G + C+D+DEC + P S
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDEC----------------SLKP---------S 210
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLD 347
C C N G FECEC GY + ++ C D
Sbjct: 211 ICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
Score = 47.6 bits (108), Expect = 9e-05
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 400 GFAKLDGAT-CRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF L C+DVDEC+L +C C N G + C+CP G
Sbjct: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
Score = 36.3 bits (80), Expect = 0.22
Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 25/118 (21%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C NT G + C C+ G+V+ + + C D S + A + EC C G
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNIPGDFECECPEG 231
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
+ L +C D+DEC S +CA CVN G Y C C
Sbjct: 232 YRYN-------------------LKSKSCEDIDEC--SENMCAQ-LCVNYPGGYTCYC 267
Score = 31.1 bits (67), Expect = 8.4
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 406 GATCR-DVDECALSAELCAGGT--CVNTDGSYRCDCPPGLTL 444
G C D++EC + + G + C NT GSY C C G +
Sbjct: 151 GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 192
>BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein.
Length = 676
Score = 106 bits (255), Expect = 1e-22
Identities = 60/156 (38%), Positives = 80/156 (51%), Gaps = 15/156 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRV---CRRGRCRNTAGSYTCLCEP 67
CK+ F C CKPG++ G C D++EC+D + C + C NT GSY C C+
Sbjct: 134 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKN 188
Query: 68 GFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + C DVDEC+ S+C C N G F+C C GYR +C D+DEC
Sbjct: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS 248
Query: 126 EQRVCRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
E +C C N PG + C C GF L+ D ++C
Sbjct: 249 E-NMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 85.8 bits (203), Expect = 3e-16
Identities = 44/125 (35%), Positives = 63/125 (50%), Gaps = 7/125 (5%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C+ IC N G + C CK G+ S C+DVDEC P +C C+N G +
Sbjct: 168 NGG-CSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFE 225
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEA--GYRPTATRGACV 119
C C G+ + C D+DEC +++MC CVN G + C C+ G++ + +C
Sbjct: 226 CECPEGYRYNLKSKSCEDIDEC-SENMC-AQLCVNYPGGYTCYCDGKKGFKLAQDQKSCE 283
Query: 120 DVDEC 124
V C
Sbjct: 284 VVSVC 288
Score = 80.2 bits (189), Expect = 1e-14
Identities = 39/112 (34%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
Query: 177 GSELYAVLCPEGPSKDNGGADINEC---TAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
G + C G + DINEC + + G C C+N Y C C G+ ++
Sbjct: 137 GKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSN 195
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C+D+DEC + S C C+N G F C CPEG R+ + + C DIDEC
Sbjct: 196 KKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC 247
Score = 51.6 bits (118), Expect = 6e-06
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 32/153 (20%)
Query: 199 NECTAVP-GACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCAGGQ--C 254
++C+ +P + SC++ + + C C PG+ + C DI+EC + G C
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK---CEFDINECKDPSNINGGCSQIC 175
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NT GS+ C C G + C+D+DEC + P S
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDEC----------------SLKP---------S 210
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLD 347
C C N G FECEC GY + ++ C D
Sbjct: 211 ICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
Score = 47.6 bits (108), Expect = 9e-05
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 400 GFAKLDGAT-CRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF L C+DVDEC+L +C C N G + C+CP G
Sbjct: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
Score = 36.3 bits (80), Expect = 0.22
Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 25/118 (21%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C NT G + C C+ G+V+ + + C D S + A + EC C G
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNIPGDFECECPEG 231
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
+ L +C D+DEC S +CA CVN G Y C C
Sbjct: 232 YRYN-------------------LKSKSCEDIDEC--SENMCAQ-LCVNYPGGYTCYC 267
Score = 31.1 bits (67), Expect = 8.4
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 406 GATCR-DVDECALSAELCAGGT--CVNTDGSYRCDCPPGLTL 444
G C D++EC + + G + C NT GSY C C G +
Sbjct: 151 GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 192
>AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein.
Length = 497
Score = 106 bits (255), Expect = 1e-22
Identities = 60/156 (38%), Positives = 80/156 (51%), Gaps = 15/156 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRV---CRRGRCRNTAGSYTCLCEP 67
CK+ F C CKPG++ G C D++EC+D + C + C NT GSY C C+
Sbjct: 134 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKN 188
Query: 68 GFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + C DVDEC+ S+C C N G F+C C GYR +C D+DEC
Sbjct: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS 248
Query: 126 EQRVCRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
E +C C N PG + C C GF L+ D ++C
Sbjct: 249 E-NMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 85.8 bits (203), Expect = 3e-16
Identities = 44/125 (35%), Positives = 63/125 (50%), Gaps = 7/125 (5%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C+ IC N G + C CK G+ S C+DVDEC P +C C+N G +
Sbjct: 168 NGG-CSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFE 225
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEA--GYRPTATRGACV 119
C C G+ + C D+DEC +++MC CVN G + C C+ G++ + +C
Sbjct: 226 CECPEGYRYNLKSKSCEDIDEC-SENMC-AQLCVNYPGGYTCYCDGKKGFKLAQDQKSCE 283
Query: 120 DVDEC 124
V C
Sbjct: 284 VVSVC 288
Score = 80.2 bits (189), Expect = 1e-14
Identities = 39/112 (34%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
Query: 177 GSELYAVLCPEGPSKDNGGADINEC---TAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
G + C G + DINEC + + G C C+N Y C C G+ ++
Sbjct: 137 GKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSN 195
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C+D+DEC + S C C+N G F C CPEG R+ + + C DIDEC
Sbjct: 196 KKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC 247
Score = 51.6 bits (118), Expect = 6e-06
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 32/153 (20%)
Query: 199 NECTAVP-GACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCAGGQ--C 254
++C+ +P + SC++ + + C C PG+ + C DI+EC + G C
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK---CEFDINECKDPSNINGGCSQIC 175
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NT GS+ C C G + C+D+DEC + P S
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDEC----------------SLKP---------S 210
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLD 347
C C N G FECEC GY + ++ C D
Sbjct: 211 ICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
Score = 47.6 bits (108), Expect = 9e-05
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 400 GFAKLDGAT-CRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF L C+DVDEC+L +C C N G + C+CP G
Sbjct: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
Score = 36.3 bits (80), Expect = 0.22
Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 25/118 (21%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C NT G + C C+ G+V+ + + C D S + A + EC C G
Sbjct: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNIPGDFECECPEG 231
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
+ L +C D+DEC S +CA CVN G Y C C
Sbjct: 232 YRYN-------------------LKSKSCEDIDEC--SENMCAQ-LCVNYPGGYTCYC 267
Score = 31.1 bits (67), Expect = 8.4
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 406 GATCR-DVDECALSAELCAGGT--CVNTDGSYRCDCPPGLTL 444
G C D++EC + + G + C NT GSY C C G +
Sbjct: 151 GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 192
>X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA for
protein S. ).
Length = 650
Score = 104 bits (249), Expect = 7e-22
Identities = 60/156 (38%), Positives = 79/156 (50%), Gaps = 15/156 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRV---CRRGRCRNTAGSYTCLCEP 67
CK+ F C CKPG++ G C D++EC+D + C + C NT GSY C C+
Sbjct: 108 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKN 162
Query: 68 GFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + C DVDEC+ S+C C N G F+C C GYR +C D+DEC
Sbjct: 163 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECS 222
Query: 126 EQRVCRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
E +C C N PG C C GF L+ D ++C
Sbjct: 223 E-NMCAQ-LCVNYPGGHTCYCDGKKGFKLAQDQKSC 256
Score = 84.2 bits (199), Expect = 8e-16
Identities = 44/125 (35%), Positives = 62/125 (49%), Gaps = 7/125 (5%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C+ IC N G + C CK G+ S C+DVDEC P +C C+N G +
Sbjct: 142 NGG-CSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFE 199
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEA--GYRPTATRGACV 119
C C G+ + C D+DEC +++MC CVN G C C+ G++ + +C
Sbjct: 200 CECPEGYRYNLKSKSCEDIDEC-SENMC-AQLCVNYPGGHTCYCDGKKGFKLAQDQKSCE 257
Query: 120 DVDEC 124
V C
Sbjct: 258 VVSVC 262
Score = 80.2 bits (189), Expect = 1e-14
Identities = 39/112 (34%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
Query: 177 GSELYAVLCPEGPSKDNGGADINEC---TAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
G + C G + DINEC + + G C C+N Y C C G+ ++
Sbjct: 111 GKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSN 169
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C+D+DEC + S C C+N G F C CPEG R+ + + C DIDEC
Sbjct: 170 KKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDEC 221
Score = 51.2 bits (117), Expect = 7e-06
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 32/153 (20%)
Query: 199 NECTAVP-GACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCAGGQ--C 254
++C+ +P + SC++ + + C C PG+ + C DI+EC + G C
Sbjct: 93 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK---CEFDINECKDPSNINGGCSQIC 149
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NT GS+ C C G + C+D+DEC + P S
Sbjct: 150 DNTPGSYHCSCKNGFVMLSNKKDCKDVDEC----------------SLKP---------S 184
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLD 347
C C N G FECEC GY + ++ C D
Sbjct: 185 ICGTAVCKNILGDFECECPEGYRYNLKSKSCED 217
Score = 46.4 bits (105), Expect = 2e-04
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 400 GFAKLDGAT-CRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF L C+DVDEC+L +C C N G + C+CP G
Sbjct: 163 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEG 205
Score = 37.1 bits (82), Expect = 0.13
Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 25/118 (21%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C NT G + C C+ G+V+ + + C D S + A +L EC C G
Sbjct: 149 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNILGDFECECPEG 205
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
+ L +C D+DEC S +CA CVN G + C C
Sbjct: 206 YRYN-------------------LKSKSCEDIDEC--SENMCA-QLCVNYPGGHTCYC 241
Score = 31.1 bits (67), Expect = 8.4
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 406 GATCR-DVDECALSAELCAGGT--CVNTDGSYRCDCPPGLTL 444
G C D++EC + + G + C NT GSY C C G +
Sbjct: 125 GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 166
>M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein.
Length = 650
Score = 104 bits (249), Expect = 7e-22
Identities = 60/156 (38%), Positives = 79/156 (50%), Gaps = 15/156 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRV---CRRGRCRNTAGSYTCLCEP 67
CK+ F C CKPG++ G C D++EC+D + C + C NT GSY C C+
Sbjct: 108 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKN 162
Query: 68 GFAPTAAGY-CADVDECAAD-SMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE 125
GF + C DVDEC+ S+C C N G F+C C GYR +C D+DEC
Sbjct: 163 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECS 222
Query: 126 EQRVCRNGRCHNTPGSFRCEC--LPGFTLSNDGRTC 159
E +C C N PG C C GF L+ D ++C
Sbjct: 223 E-NMCAQ-LCVNYPGGHTCYCDGKKGFKLAQDQKSC 256
Score = 84.2 bits (199), Expect = 8e-16
Identities = 44/125 (35%), Positives = 62/125 (49%), Gaps = 7/125 (5%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
NGG C+ IC N G + C CK G+ S C+DVDEC P +C C+N G +
Sbjct: 142 NGG-CSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFE 199
Query: 63 CLCEPGFA-PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEA--GYRPTATRGACV 119
C C G+ + C D+DEC +++MC CVN G C C+ G++ + +C
Sbjct: 200 CECPEGYRYNLKSKSCEDIDEC-SENMC-AQLCVNYPGGHTCYCDGKKGFKLAQDQKSCE 257
Query: 120 DVDEC 124
V C
Sbjct: 258 VVSVC 262
Score = 80.2 bits (189), Expect = 1e-14
Identities = 39/112 (34%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
Query: 177 GSELYAVLCPEGPSKDNGGADINEC---TAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
G + C G + DINEC + + G C C+N Y C C G+ ++
Sbjct: 111 GKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSN 169
Query: 234 GL-CRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC 284
C+D+DEC + S C C+N G F C CPEG R+ + + C DIDEC
Sbjct: 170 KKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDEC 221
Score = 51.2 bits (117), Expect = 7e-06
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 32/153 (20%)
Query: 199 NECTAVP-GACPHGSCENLEPGYRCICDPGYHPDADGLCR-DIDECDMHQSYCAGGQ--C 254
++C+ +P + SC++ + + C C PG+ + C DI+EC + G C
Sbjct: 93 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK---CEFDINECKDPSNINGGCSQIC 149
Query: 255 RNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS 314
NT GS+ C C G + C+D+DEC + P S
Sbjct: 150 DNTPGSYHCSCKNGFVMLSNKKDCKDVDEC----------------SLKP---------S 184
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLD 347
C C N G FECEC GY + ++ C D
Sbjct: 185 ICGTAVCKNILGDFECECPEGYRYNLKSKSCED 217
Score = 46.4 bits (105), Expect = 2e-04
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 400 GFAKLDGAT-CRDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
GF L C+DVDEC+L +C C N G + C+CP G
Sbjct: 163 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEG 205
Score = 37.1 bits (82), Expect = 0.13
Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 25/118 (21%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C NT G + C C+ G+V+ + + C D S + A +L EC C G
Sbjct: 149 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG---TAVCKNILGDFECECPEG 205
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDC 438
+ L +C D+DEC S +CA CVN G + C C
Sbjct: 206 YRYN-------------------LKSKSCEDIDEC--SENMCA-QLCVNYPGGHTCYC 241
Score = 31.1 bits (67), Expect = 8.4
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 406 GATCR-DVDECALSAELCAGGT--CVNTDGSYRCDCPPGLTL 444
G C D++EC + + G + C NT GSY C C G +
Sbjct: 125 GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVM 166
>AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein
protein.
Length = 723
Score = 103 bits (248), Expect = 1e-21
Identities = 87/276 (31%), Positives = 115/276 (41%), Gaps = 32/276 (11%)
Query: 4 GGMCTNGIC-KNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYT 62
G CT IC D KPG G R DEC P C G C+ +
Sbjct: 218 GPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPG-CLHGTCQQP---WQ 273
Query: 63 CLCEPGFAPTAAGYC-ADVDECAADSMCKGGR-CVNS-EGSFQCVCEAGYRPTATRGAC- 118
C C+ G+ +C D++ C CK G C N+ +GS+ C C GY T C
Sbjct: 274 CNCQEGWGGL---FCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGY----TGATCE 326
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPA 175
+ +DEC+ G C + S+ C C PGF TC G C P
Sbjct: 327 LGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPD 386
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADG 234
G Y+ CP G S N I+ C++ P C +G+ C +L Y C C G+ +
Sbjct: 387 GG---YSCRCPVGYSGFNCEKKIDYCSSSP--CSNGAKCVDLGDAYLCRCQAGF---SGR 438
Query: 235 LCRD-IDECDMHQSYCA-GGQCRNTAGSFTCVCPEG 268
C D +D+C S CA GG CR+ F+C CP G
Sbjct: 439 HCDDNVDDCA--SSPCANGGTCRDGVNDFSCTCPPG 472
Score = 92.3 bits (219), Expect = 3e-18
Identities = 69/266 (25%), Positives = 107/266 (40%), Gaps = 28/266 (10%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGR-CRNTA-GSYTC 63
C +G C+ ++C C+ G+ G C +D++ C + + C+ G C NT GSYTC
Sbjct: 263 CLHGTCQQ---PWQCNCQEGWG----GLFCNQDLNYCTHH-KPCKNGATCTNTGQGSYTC 314
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PG+ T A +DEC GG C + E S+ C C G+ +
Sbjct: 315 SCRPGY--TGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICE---LSAMT 369
Query: 124 CEEQRVCRNGRCHNTP-GSFRCECLPGFTLSNDGRT---CLGLKLGWGVSCQACPAQGSE 179
C + GRC ++P G + C C G++ N + C G C +
Sbjct: 370 CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKC----VDLGD 425
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
Y C G S + ++++C + P A G+C + + C C PGY +
Sbjct: 426 AYLCRCQAGFSGRHCDDNVDDCASSPCA-NGGTCRDGVNDFSCTCPPGY--TGRNCSAPV 482
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVC 265
C+ H G C + C C
Sbjct: 483 SRCE-HAPCHNGATCHQRGHGYVCEC 507
Score = 60.1 bits (139), Expect = 2e-08
Identities = 51/155 (32%), Positives = 74/155 (47%), Gaps = 21/155 (13%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-C-RDIDECDMHQSYCAGG 252
G +EC PG C HG+C+ +P ++C C G+ GL C +D++ C H+ G
Sbjct: 251 GRYCDECIRYPG-CLHGTCQ--QP-WQCNCQEGW----GGLFCNQDLNYCTHHKPCKNGA 302
Query: 253 QCRNTA-GSFTCVCPEG-TRHEPELQLCR-DIDECEGETETHYIESDYERGDIPPTFPTR 309
C NT GS+TC C G T EL + D C+ +E+ Y P +
Sbjct: 303 TCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKI 362
Query: 310 TELAS------PCDNG-RCINT-HGGFECECELGY 336
EL++ PC NG RC ++ GG+ C C +GY
Sbjct: 363 CELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGY 397
Score = 39.5 bits (88), Expect = 0.024
Identities = 19/38 (50%), Positives = 23/38 (60%), Gaps = 4/38 (10%)
Query: 406 GATCR-DVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
GATC +DEC S C GG+C + + SY C CPPG
Sbjct: 322 GATCELGIDECDPSP--CKNGGSCTDLENSYSCTCPPG 357
Score = 33.9 bits (74), Expect = 1.2
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 2/40 (5%)
Query: 406 GATC-RDVDECALSAELCAGGTCVNT-DGSYRCDCPPGLT 443
G C +D++ C G TC NT GSY C C PG T
Sbjct: 282 GLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYT 321
Score = 31.9 bits (69), Expect = 4.8
Identities = 16/34 (47%), Positives = 16/34 (47%), Gaps = 7/34 (20%)
Query: 415 CALSAELCAGGTCVN-------TDGSYRCDCPPG 441
C LSA CA G C N DG Y C CP G
Sbjct: 363 CELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVG 396
>M16552-1|AAB59508.1| 575|Homo sapiens THBD protein.
Length = 575
Score = 103 bits (247), Expect = 1e-21
Identities = 99/362 (27%), Positives = 144/362 (39%), Gaps = 31/362 (8%)
Query: 21 CICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CAD 79
C PG G +C C C G+ C C G A A G C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 80 VDECAADSMCKGGRCVNSE--GSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCH 136
+ + +C+ N + GS+ C+CE GYR A + C DVD+C E C RC
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCV 341
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGSELYAVLCPEGPSKDNGG 195
NT G F C C P + L DG + + +C+ C Y +C EG +
Sbjct: 342 NTQGGFECHCYPNYDLV-DGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHE 400
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
+ ACP N + C C GY D +C DIDEC+ + +C+ G C
Sbjct: 401 PHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGFICTDIDECE-NGGFCS-GVCH 456
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDI-DECE-GETETHYIESDYERGDIPPTFPTRTELA 313
N G+F C+C P+ L R I +C+ G+ + D G+ PP+ PT
Sbjct: 457 NLPGTFECIC------GPDSALARHIGTDCDSGKVD----GGDSGSGEPPPS-PTPGSTL 505
Query: 314 SPCDNGRCINTHGGFECE---CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELL 370
+P G H G L V+ A C ++ R ++ +C A + E++
Sbjct: 506 TPPAVGL---VHSGLLIGISIASLCLVVALLALLCHLRKKQGAARAKMEYKCAAPSKEVV 562
Query: 371 LR 372
L+
Sbjct: 563 LQ 564
Score = 67.7 bits (158), Expect = 8e-11
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 6 MCTNGICKNID--GGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
+C + N D G + C+C+ GY ++ C DVD+C P C + RC NT G + C
Sbjct: 291 LCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFEC 349
Query: 64 LCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C P + G C + VD C + C+ ++ S+ CVC G+ P +
Sbjct: 350 HCYPNY-DLVDGECVEPVDPCFR-ANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM- 406
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
C Q C NT S CEC G+ L +DG C
Sbjct: 407 FC-NQTACPADCDPNTQAS--CECPEGYIL-DDGFIC 439
Score = 66.1 bits (154), Expect = 2e-10
Identities = 68/266 (25%), Positives = 97/266 (36%), Gaps = 58/266 (21%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG---LCRDIDEC-DMHQSYCAGGQCR 255
+C+ G C H +C + RC C G ADG C D+ + +C
Sbjct: 244 DCSVENGGCEH-ACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP-- 300
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
+ GS++C+C G R + C D+D+C E SP
Sbjct: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEP-------------------------SP 335
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C RC+NT GGFEC C Y D C++ C+R + QC+ L C
Sbjct: 336 CPQ-RCVNTQGGFECHCYPNY--DLVDGECVEPV-DPCFRANCEYQCQPLNQTSYL---C 388
Query: 376 CCSVGLA-----------------WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALS 418
C+ G A + +G+ DG C D+DEC +
Sbjct: 389 VCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECE-N 447
Query: 419 AELCAGGTCVNTDGSYRCDCPPGLTL 444
C+ G C N G++ C C P L
Sbjct: 448 GGFCS-GVCHNLPGTFECICGPDSAL 472
Score = 37.5 bits (83), Expect = 0.097
Identities = 14/23 (60%), Positives = 17/23 (73%), Gaps = 1/23 (4%)
Query: 3 NGGMCTNGICKNIDGGFECICKP 25
NGG C+ G+C N+ G FECIC P
Sbjct: 447 NGGFCS-GVCHNLPGTFECICGP 468
>J02973-1|AAA61175.1| 575|Homo sapiens THBD protein.
Length = 575
Score = 103 bits (247), Expect = 1e-21
Identities = 99/362 (27%), Positives = 144/362 (39%), Gaps = 31/362 (8%)
Query: 21 CICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CAD 79
C PG G +C C C G+ C C G A A G C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 80 VDECAADSMCKGGRCVNSE--GSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCH 136
+ + +C+ N + GS+ C+CE GYR A + C DVD+C E C RC
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCV 341
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGSELYAVLCPEGPSKDNGG 195
NT G F C C P + L DG + + +C+ C Y +C EG +
Sbjct: 342 NTQGGFECHCYPNYDLV-DGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHE 400
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
+ ACP N + C C GY D +C DIDEC+ + +C+ G C
Sbjct: 401 PHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGFICTDIDECE-NGGFCS-GVCH 456
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDI-DECE-GETETHYIESDYERGDIPPTFPTRTELA 313
N G+F C+C P+ L R I +C+ G+ + D G+ PP+ PT
Sbjct: 457 NLPGTFECIC------GPDSALARHIGTDCDSGKVD----GGDSGSGEPPPS-PTPGSTL 505
Query: 314 SPCDNGRCINTHGGFECE---CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELL 370
+P G H G L V+ A C ++ R ++ +C A + E++
Sbjct: 506 TPPAVGL---VHSGLLIGISIASLCLVVALLALLCHLRKKQGAARAKMEYKCAAPSKEVV 562
Query: 371 LR 372
L+
Sbjct: 563 LQ 564
Score = 67.7 bits (158), Expect = 8e-11
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 6 MCTNGICKNID--GGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
+C + N D G + C+C+ GY ++ C DVD+C P C + RC NT G + C
Sbjct: 291 LCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFEC 349
Query: 64 LCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C P + G C + VD C + C+ ++ S+ CVC G+ P +
Sbjct: 350 HCYPNY-DLVDGECVEPVDPCFR-ANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM- 406
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
C Q C NT S CEC G+ L +DG C
Sbjct: 407 FC-NQTACPADCDPNTQAS--CECPEGYIL-DDGFIC 439
Score = 66.1 bits (154), Expect = 2e-10
Identities = 68/266 (25%), Positives = 97/266 (36%), Gaps = 58/266 (21%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG---LCRDIDEC-DMHQSYCAGGQCR 255
+C+ G C H +C + RC C G ADG C D+ + +C
Sbjct: 244 DCSVENGGCEH-ACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP-- 300
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
+ GS++C+C G R + C D+D+C E SP
Sbjct: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEP-------------------------SP 335
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C RC+NT GGFEC C Y D C++ C+R + QC+ L C
Sbjct: 336 CPQ-RCVNTQGGFECHCYPNY--DLVDGECVEPV-DPCFRANCEYQCQPLNQTSYL---C 388
Query: 376 CCSVGLA-----------------WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALS 418
C+ G A + +G+ DG C D+DEC +
Sbjct: 389 VCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECE-N 447
Query: 419 AELCAGGTCVNTDGSYRCDCPPGLTL 444
C+ G C N G++ C C P L
Sbjct: 448 GGFCS-GVCHNLPGTFECICGPDSAL 472
Score = 37.5 bits (83), Expect = 0.097
Identities = 14/23 (60%), Positives = 17/23 (73%), Gaps = 1/23 (4%)
Query: 3 NGGMCTNGICKNIDGGFECICKP 25
NGG C+ G+C N+ G FECIC P
Sbjct: 447 NGGFCS-GVCHNLPGTFECICGP 468
>BC053357-1|AAH53357.1| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 103 bits (247), Expect = 1e-21
Identities = 99/362 (27%), Positives = 144/362 (39%), Gaps = 31/362 (8%)
Query: 21 CICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CAD 79
C PG G +C C C G+ C C G A A G C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 80 VDECAADSMCKGGRCVNSE--GSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCH 136
+ + +C+ N + GS+ C+CE GYR A + C DVD+C E C RC
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCV 341
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGSELYAVLCPEGPSKDNGG 195
NT G F C C P + L DG + + +C+ C Y +C EG +
Sbjct: 342 NTQGGFECHCYPNYDLV-DGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHE 400
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
+ ACP N + C C GY D +C DIDEC+ + +C+ G C
Sbjct: 401 PHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGFICTDIDECE-NGGFCS-GVCH 456
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDI-DECE-GETETHYIESDYERGDIPPTFPTRTELA 313
N G+F C+C P+ L R I +C+ G+ + D G+ PP+ PT
Sbjct: 457 NLPGTFECIC------GPDSALARHIGTDCDSGKVD----GGDSGSGEPPPS-PTPGSTL 505
Query: 314 SPCDNGRCINTHGGFECE---CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELL 370
+P G H G L V+ A C ++ R ++ +C A + E++
Sbjct: 506 TPPAVGL---VHSGLLIGISIASLCLVVALLALLCHLRKKQGAARAKMEYKCAAPSKEVV 562
Query: 371 LR 372
L+
Sbjct: 563 LQ 564
Score = 67.7 bits (158), Expect = 8e-11
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 6 MCTNGICKNID--GGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
+C + N D G + C+C+ GY ++ C DVD+C P C + RC NT G + C
Sbjct: 291 LCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFEC 349
Query: 64 LCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C P + G C + VD C + C+ ++ S+ CVC G+ P +
Sbjct: 350 HCYPNY-DLVDGECVEPVDPCFR-ANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM- 406
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
C Q C NT S CEC G+ L +DG C
Sbjct: 407 FC-NQTACPADCDPNTQAS--CECPEGYIL-DDGFIC 439
Score = 66.1 bits (154), Expect = 2e-10
Identities = 68/266 (25%), Positives = 97/266 (36%), Gaps = 58/266 (21%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG---LCRDIDEC-DMHQSYCAGGQCR 255
+C+ G C H +C + RC C G ADG C D+ + +C
Sbjct: 244 DCSVENGGCEH-ACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP-- 300
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
+ GS++C+C G R + C D+D+C E SP
Sbjct: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEP-------------------------SP 335
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C RC+NT GGFEC C Y D C++ C+R + QC+ L C
Sbjct: 336 CPQ-RCVNTQGGFECHCYPNY--DLVDGECVEPV-DPCFRANCEYQCQPLNQTSYL---C 388
Query: 376 CCSVGLA-----------------WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALS 418
C+ G A + +G+ DG C D+DEC +
Sbjct: 389 VCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECE-N 447
Query: 419 AELCAGGTCVNTDGSYRCDCPPGLTL 444
C+ G C N G++ C C P L
Sbjct: 448 GGFCS-GVCHNLPGTFECICGPDSAL 472
Score = 37.5 bits (83), Expect = 0.097
Identities = 14/23 (60%), Positives = 17/23 (73%), Gaps = 1/23 (4%)
Query: 3 NGGMCTNGICKNIDGGFECICKP 25
NGG C+ G+C N+ G FECIC P
Sbjct: 447 NGGFCS-GVCHNLPGTFECICGP 468
>AL049651-2|CAB51954.1| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 103 bits (247), Expect = 1e-21
Identities = 99/362 (27%), Positives = 144/362 (39%), Gaps = 31/362 (8%)
Query: 21 CICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CAD 79
C PG G +C C C G+ C C G A A G C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 80 VDECAADSMCKGGRCVNSE--GSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCH 136
+ + +C+ N + GS+ C+CE GYR A + C DVD+C E C RC
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCV 341
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGSELYAVLCPEGPSKDNGG 195
NT G F C C P + L DG + + +C+ C Y +C EG +
Sbjct: 342 NTQGGFECHCYPNYDLV-DGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHE 400
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
+ ACP N + C C GY D +C DIDEC+ + +C+ G C
Sbjct: 401 PHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGFICTDIDECE-NGGFCS-GVCH 456
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDI-DECE-GETETHYIESDYERGDIPPTFPTRTELA 313
N G+F C+C P+ L R I +C+ G+ + D G+ PP+ PT
Sbjct: 457 NLPGTFECIC------GPDSALARHIGTDCDSGKVD----GGDSGSGEPPPS-PTPGSTL 505
Query: 314 SPCDNGRCINTHGGFECE---CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELL 370
+P G H G L V+ A C ++ R ++ +C A + E++
Sbjct: 506 TPPAVGL---VHSGLLIGISIASLCLVVALLALLCHLRKKQGAARAKMEYKCAAPSKEVV 562
Query: 371 LR 372
L+
Sbjct: 563 LQ 564
Score = 67.7 bits (158), Expect = 8e-11
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 6 MCTNGICKNID--GGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
+C + N D G + C+C+ GY ++ C DVD+C P C + RC NT G + C
Sbjct: 291 LCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFEC 349
Query: 64 LCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C P + G C + VD C + C+ ++ S+ CVC G+ P +
Sbjct: 350 HCYPNY-DLVDGECVEPVDPCFR-ANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM- 406
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
C Q C NT S CEC G+ L +DG C
Sbjct: 407 FC-NQTACPADCDPNTQAS--CECPEGYIL-DDGFIC 439
Score = 66.1 bits (154), Expect = 2e-10
Identities = 68/266 (25%), Positives = 97/266 (36%), Gaps = 58/266 (21%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG---LCRDIDEC-DMHQSYCAGGQCR 255
+C+ G C H +C + RC C G ADG C D+ + +C
Sbjct: 244 DCSVENGGCEH-ACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP-- 300
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
+ GS++C+C G R + C D+D+C E SP
Sbjct: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEP-------------------------SP 335
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C RC+NT GGFEC C Y D C++ C+R + QC+ L C
Sbjct: 336 CPQ-RCVNTQGGFECHCYPNY--DLVDGECVEPV-DPCFRANCEYQCQPLNQTSYL---C 388
Query: 376 CCSVGLA-----------------WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALS 418
C+ G A + +G+ DG C D+DEC +
Sbjct: 389 VCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECE-N 447
Query: 419 AELCAGGTCVNTDGSYRCDCPPGLTL 444
C+ G C N G++ C C P L
Sbjct: 448 GGFCS-GVCHNLPGTFECICGPDSAL 472
Score = 37.5 bits (83), Expect = 0.097
Identities = 14/23 (60%), Positives = 17/23 (73%), Gaps = 1/23 (4%)
Query: 3 NGGMCTNGICKNIDGGFECICKP 25
NGG C+ G+C N+ G FECIC P
Sbjct: 447 NGGFCS-GVCHNLPGTFECICGP 468
>AF495471-1|AAM03232.1| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 103 bits (247), Expect = 1e-21
Identities = 99/362 (27%), Positives = 144/362 (39%), Gaps = 31/362 (8%)
Query: 21 CICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CAD 79
C PG G +C C C G+ C C G A A G C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 80 VDECAADSMCKGGRCVNSE--GSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCH 136
+ + +C+ N + GS+ C+CE GYR A + C DVD+C E C RC
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCV 341
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGSELYAVLCPEGPSKDNGG 195
NT G F C C P + L DG + + +C+ C Y +C EG +
Sbjct: 342 NTQGGFECHCYPNYDLV-DGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHE 400
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
+ ACP N + C C GY D +C DIDEC+ + +C+ G C
Sbjct: 401 PHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGFICTDIDECE-NGGFCS-GVCH 456
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDI-DECE-GETETHYIESDYERGDIPPTFPTRTELA 313
N G+F C+C P+ L R I +C+ G+ + D G+ PP+ PT
Sbjct: 457 NLPGTFECIC------GPDSALARHIGTDCDSGKVD----GGDSGSGEPPPS-PTPGSTL 505
Query: 314 SPCDNGRCINTHGGFECE---CELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELL 370
+P G H G L V+ A C ++ R ++ +C A + E++
Sbjct: 506 TPPAVGL---VHSGLLIGISIASLCLVVALLALLCHLRKKQGAARAKMEYKCAAPSKEVV 562
Query: 371 LR 372
L+
Sbjct: 563 LQ 564
Score = 67.7 bits (158), Expect = 8e-11
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 6 MCTNGICKNID--GGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
+C + N D G + C+C+ GY ++ C DVD+C P C + RC NT G + C
Sbjct: 291 LCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFEC 349
Query: 64 LCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C P + G C + VD C + C+ ++ S+ CVC G+ P +
Sbjct: 350 HCYPNY-DLVDGECVEPVDPCFR-ANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM- 406
Query: 123 ECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
C Q C NT S CEC G+ L +DG C
Sbjct: 407 FC-NQTACPADCDPNTQAS--CECPEGYIL-DDGFIC 439
Score = 66.1 bits (154), Expect = 2e-10
Identities = 68/266 (25%), Positives = 97/266 (36%), Gaps = 58/266 (21%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG---LCRDIDEC-DMHQSYCAGGQCR 255
+C+ G C H +C + RC C G ADG C D+ + +C
Sbjct: 244 DCSVENGGCEH-ACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP-- 300
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
+ GS++C+C G R + C D+D+C E SP
Sbjct: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEP-------------------------SP 335
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C RC+NT GGFEC C Y D C++ C+R + QC+ L C
Sbjct: 336 CPQ-RCVNTQGGFECHCYPNY--DLVDGECVEPV-DPCFRANCEYQCQPLNQTSYL---C 388
Query: 376 CCSVGLA-----------------WGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALS 418
C+ G A + +G+ DG C D+DEC +
Sbjct: 389 VCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECE-N 447
Query: 419 AELCAGGTCVNTDGSYRCDCPPGLTL 444
C+ G C N G++ C C P L
Sbjct: 448 GGFCS-GVCHNLPGTFECICGPDSAL 472
Score = 37.5 bits (83), Expect = 0.097
Identities = 14/23 (60%), Positives = 17/23 (73%), Gaps = 1/23 (4%)
Query: 3 NGGMCTNGICKNIDGGFECICKP 25
NGG C+ G+C N+ G FECIC P
Sbjct: 447 NGGFCS-GVCHNLPGTFECICGP 468
>X05495-1|CAA29045.1| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 103 bits (246), Expect = 2e-21
Identities = 74/250 (29%), Positives = 101/250 (40%), Gaps = 12/250 (4%)
Query: 21 CICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CAD 79
C PG G +C C C G+ C C G A A G C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 80 VDECAADSMCKGGRCVNSE--GSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCH 136
+ + +C+ N + GS+ C+CE GYR A + C DVD+C E C RC
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCV 341
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGSELYAVLCPEGPSKDNGG 195
NT G F C C P + L DG + + +C+ C Y +C EG +
Sbjct: 342 NTQGGFECHCYPNYDLV-DGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHE 400
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
+ ACP N + C C GY D +C DIDEC+ + +C+ G C
Sbjct: 401 PHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGFICTDIDECE-NGGFCS-GVCH 456
Query: 256 NTAGSFTCVC 265
N G+F C+C
Sbjct: 457 NLPGTFECIC 466
Score = 87.4 bits (207), Expect = 9e-17
Identities = 75/235 (31%), Positives = 99/235 (42%), Gaps = 26/235 (11%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRD--VDECRDNPRVCRRGRCRNT--A 58
NGG C + C I G C C G ++G C C D +C N
Sbjct: 249 NGG-CEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCND---LCEHFCVPNPDQP 303
Query: 59 GSYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
GSY+C+CE G+ A + C DVD+C + RCVN++G F+C C Y G
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNY--DLVDGE 361
Query: 118 CVD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFT-LSNDGRTCLGLKLGWGVSCQACPA 175
CV+ VD C C S+ C C GF + ++ C + ACPA
Sbjct: 362 CVEPVDPCFRAN-CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMF-----CNQTACPA 415
Query: 176 Q--GSELYAVLCPEGPSKDNGG--ADINECTAVPGACPHGSCENLEPGYRCICDP 226
+ + CPEG D+G DI+EC G C G C NL + CIC P
Sbjct: 416 DCDPNTQASCECPEGYILDDGFICTDIDECEN-GGFCS-GVCHNLPGTFECICGP 468
Score = 73.3 bits (172), Expect = 2e-12
Identities = 59/177 (33%), Positives = 71/177 (40%), Gaps = 11/177 (6%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDEC-RDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C N GGFEC C P Y+ +G VD C R N C SY C+C GFA
Sbjct: 340 CVNTQGGFECHCYPNYDL-VDGECVEPVDPCFRAN---CEYQCQPLNQTSYLCVCAEGFA 395
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
P C + C N++ S C C GY C D+DECE C
Sbjct: 396 PIPHEPHRCQMFCN-QTACPADCDPNTQAS--CECPEGYI-LDDGFICTDIDECENGGFC 451
Query: 131 RNGRCHNTPGSFRCECLPGFTL-SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCP 186
+G CHN PG+F C C P L + G C K+ G S P + L P
Sbjct: 452 -SGVCHNLPGTFECICGPDSALVRHIGTDCDSGKVDGGDSGSGEPPPSPTPGSTLTP 507
Score = 66.1 bits (154), Expect = 2e-10
Identities = 68/266 (25%), Positives = 97/266 (36%), Gaps = 58/266 (21%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG---LCRDIDEC-DMHQSYCAGGQCR 255
+C+ G C H +C + RC C G ADG C D+ + +C
Sbjct: 244 DCSVENGGCEH-ACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP-- 300
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
+ GS++C+C G R + C D+D+C E SP
Sbjct: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILE-------------------------PSP 335
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C RC+NT GGFEC C Y D C++ C+R + QC+ L C
Sbjct: 336 CPQ-RCVNTQGGFECHCYPNY--DLVDGECVE-PVDPCFRANCEYQCQPLNQTSYL---C 388
Query: 376 CCSVGL-----------------AWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALS 418
C+ G A + +G+ DG C D+DEC +
Sbjct: 389 VCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECE-N 447
Query: 419 AELCAGGTCVNTDGSYRCDCPPGLTL 444
C+ G C N G++ C C P L
Sbjct: 448 GGFCS-GVCHNLPGTFECICGPDSAL 472
Score = 64.9 bits (151), Expect = 6e-10
Identities = 62/217 (28%), Positives = 92/217 (42%), Gaps = 25/217 (11%)
Query: 135 CHNTPGSFRCECLPGFTLSNDGRTCLGLKL-GWGVSCQA-CPAQGSE--LYAVLCPEG-- 188
C+ PG+ RC+C G L DGR+C C+ C + Y+ +C G
Sbjct: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYR 315
Query: 189 -PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD-IDECDMHQ 246
+ + D+++C P CP C N + G+ C C P Y DG C + +D C +
Sbjct: 316 LAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDL-VDGECVEPVDPC--FR 371
Query: 247 SYCAGGQCRN-TAGSFTCVCPEGTR---HEPE-LQLCRDIDECEGETETHYIES-DYERG 300
+ C QC+ S+ CVC EG HEP Q+ + C + + + S + G
Sbjct: 372 ANCEY-QCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEG 430
Query: 301 DIPPTFPTRTELASPCDNGR-----CINTHGGFECEC 332
I T++ C+NG C N G FEC C
Sbjct: 431 YILDDGFICTDI-DECENGGFCSGVCHNLPGTFECIC 466
Score = 54.8 bits (126), Expect = 6e-07
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 25/174 (14%)
Query: 185 CPEGPSKDNGGADINECTAVPGACPHGSCENL------EPG-YRCICDPGYHPDADG-LC 236
CP G + AD CTA + CE+ +PG Y C+C+ GY AD C
Sbjct: 267 CPAGAALQ---ADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRC 323
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVC------PEGTRHEPELQLCRDIDE--CEGET 288
D+D+C + S C +C NT G F C C +G EP R E C+
Sbjct: 324 EDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLN 382
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRC---INTHGGFECECELGYVLD 339
+T Y+ E P P R ++ C+ C + + CEC GY+LD
Sbjct: 383 QTSYLCVCAEGFAPIPHEPHRCQMF--CNQTACPADCDPNTQASCECPEGYILD 434
>D00210-1|BAA00149.1| 575|Homo sapiens thrombomodulin precursor
protein.
Length = 575
Score = 103 bits (246), Expect = 2e-21
Identities = 74/250 (29%), Positives = 101/250 (40%), Gaps = 12/250 (4%)
Query: 21 CICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CAD 79
C PG G +C C C G+ C C G A A G C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 80 VDECAADSMCKGGRCVNSE--GSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCH 136
+ + +C+ N + GS+ C+CE GYR A + C DVD+C E C RC
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCV 341
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGSELYAVLCPEGPSKDNGG 195
NT G F C C P + L DG + + +C+ C Y +C EG +
Sbjct: 342 NTQGGFECHCYPNYDLV-DGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHE 400
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
+ ACP N + C C GY D +C DIDEC+ + +C+ G C
Sbjct: 401 PHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGFICTDIDECE-NGGFCS-GVCH 456
Query: 256 NTAGSFTCVC 265
N G+F C+C
Sbjct: 457 NLPGTFECIC 466
Score = 87.4 bits (207), Expect = 9e-17
Identities = 75/235 (31%), Positives = 99/235 (42%), Gaps = 26/235 (11%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRD--VDECRDNPRVCRRGRCRNT--A 58
NGG C + C I G C C G ++G C C D +C N
Sbjct: 249 NGG-CEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCND---LCEHFCVPNPDQP 303
Query: 59 GSYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
GSY+C+CE G+ A + C DVD+C + RCVN++G F+C C Y G
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNY--DLVDGE 361
Query: 118 CVD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFT-LSNDGRTCLGLKLGWGVSCQACPA 175
CV+ VD C C S+ C C GF + ++ C + ACPA
Sbjct: 362 CVEPVDPCFRAN-CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMF-----CNQTACPA 415
Query: 176 Q--GSELYAVLCPEGPSKDNGG--ADINECTAVPGACPHGSCENLEPGYRCICDP 226
+ + CPEG D+G DI+EC G C G C NL + CIC P
Sbjct: 416 DCDPNTQASCECPEGYILDDGFICTDIDECEN-GGFCS-GVCHNLPGTFECICGP 468
Score = 73.3 bits (172), Expect = 2e-12
Identities = 59/177 (33%), Positives = 71/177 (40%), Gaps = 11/177 (6%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDEC-RDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C N GGFEC C P Y+ +G VD C R N C SY C+C GFA
Sbjct: 340 CVNTQGGFECHCYPNYDL-VDGECVEPVDPCFRAN---CEYQCQPLNQTSYLCVCAEGFA 395
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
P C + C N++ S C C GY C D+DECE C
Sbjct: 396 PIPHEPHRCQMFCN-QTACPADCDPNTQAS--CECPEGYI-LDDGFICTDIDECENGGFC 451
Query: 131 RNGRCHNTPGSFRCECLPGFTL-SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCP 186
+G CHN PG+F C C P L + G C K+ G S P + L P
Sbjct: 452 -SGVCHNLPGTFECICGPDSALVRHIGTDCDSGKVDGGDSGSGEPPPSPTPGSTLTP 507
Score = 66.1 bits (154), Expect = 2e-10
Identities = 68/266 (25%), Positives = 97/266 (36%), Gaps = 58/266 (21%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG---LCRDIDEC-DMHQSYCAGGQCR 255
+C+ G C H +C + RC C G ADG C D+ + +C
Sbjct: 244 DCSVENGGCEH-ACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP-- 300
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
+ GS++C+C G R + C D+D+C E SP
Sbjct: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILE-------------------------PSP 335
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C RC+NT GGFEC C Y D C++ C+R + QC+ L C
Sbjct: 336 CPQ-RCVNTQGGFECHCYPNY--DLVDGECVE-PVDPCFRANCEYQCQPLNQTSYL---C 388
Query: 376 CCSVGL-----------------AWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALS 418
C+ G A + +G+ DG C D+DEC +
Sbjct: 389 VCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECE-N 447
Query: 419 AELCAGGTCVNTDGSYRCDCPPGLTL 444
C+ G C N G++ C C P L
Sbjct: 448 GGFCS-GVCHNLPGTFECICGPDSAL 472
Score = 64.9 bits (151), Expect = 6e-10
Identities = 62/217 (28%), Positives = 92/217 (42%), Gaps = 25/217 (11%)
Query: 135 CHNTPGSFRCECLPGFTLSNDGRTCLGLKL-GWGVSCQA-CPAQGSE--LYAVLCPEG-- 188
C+ PG+ RC+C G L DGR+C C+ C + Y+ +C G
Sbjct: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYR 315
Query: 189 -PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD-IDECDMHQ 246
+ + D+++C P CP C N + G+ C C P Y DG C + +D C +
Sbjct: 316 LAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDL-VDGECVEPVDPC--FR 371
Query: 247 SYCAGGQCRN-TAGSFTCVCPEGTR---HEPE-LQLCRDIDECEGETETHYIES-DYERG 300
+ C QC+ S+ CVC EG HEP Q+ + C + + + S + G
Sbjct: 372 ANCEY-QCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEG 430
Query: 301 DIPPTFPTRTELASPCDNGR-----CINTHGGFECEC 332
I T++ C+NG C N G FEC C
Sbjct: 431 YILDDGFICTDI-DECENGGFCSGVCHNLPGTFECIC 466
Score = 54.8 bits (126), Expect = 6e-07
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 25/174 (14%)
Query: 185 CPEGPSKDNGGADINECTAVPGACPHGSCENL------EPG-YRCICDPGYHPDADG-LC 236
CP G + AD CTA + CE+ +PG Y C+C+ GY AD C
Sbjct: 267 CPAGAALQ---ADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRC 323
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVC------PEGTRHEPELQLCRDIDE--CEGET 288
D+D+C + S C +C NT G F C C +G EP R E C+
Sbjct: 324 EDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLN 382
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRC---INTHGGFECECELGYVLD 339
+T Y+ E P P R ++ C+ C + + CEC GY+LD
Sbjct: 383 QTSYLCVCAEGFAPIPHEPHRCQMF--CNQTACPADCDPNTQASCECPEGYILD 434
>BC053933-1|AAH53933.1| 239|Homo sapiens EMR2 protein protein.
Length = 239
Score = 103 bits (246), Expect = 2e-21
Identities = 50/113 (44%), Positives = 68/113 (60%), Gaps = 13/113 (11%)
Query: 12 CKNIDGGFECICKPGYE--SGSEGA------LCRDVDECRDNPRVCRR-GRCRNTAGSYT 62
C N +G ++C+C PGYE SG++ C+DVDEC+ NPR+C+ G C NT GSYT
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 144
Query: 63 CLCEPG--FAPTAAGYCADVDEC-AADSMCKGG-RCVNSEGSFQCVCEAGYRP 111
C C PG F P C DV+EC + + C C+N+ GS+QC C G++P
Sbjct: 145 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQP 197
Score = 94.3 bits (224), Expect = 8e-19
Identities = 57/152 (37%), Positives = 77/152 (50%), Gaps = 23/152 (15%)
Query: 21 CICKPGYESGSE-----GALCRDVDECRDNPRV-CRR-GRCRNTAGSYTCLCEPGFAPTA 73
C C PG+ S SE C D++EC +V C + C NT GSY C+C PG+ P +
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 74 AGY---------CADVDECAADS-MCKG-GRCVNSEGSFQCVCEAGYR--PTATRGACVD 120
C DVDEC + +CK G CVN+ GS+ C C G++ P + C D
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK-VCTD 163
Query: 121 VDECEE-QRVCRNG-RCHNTPGSFRCECLPGF 150
V+EC Q C + C N GS++C C PG+
Sbjct: 164 VNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 195
Score = 84.6 bits (200), Expect = 6e-16
Identities = 46/117 (39%), Positives = 63/117 (53%), Gaps = 20/117 (17%)
Query: 63 CLCEPGFAP------TAAGYCADVDECAADSMCKGGR---CVNSEGSFQCVCEAGYRPTA 113
C C PGF+ T C D++ECA S G+ C N+EGS+ CVC GY P +
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 114 --------TRGACVDVDECEEQ-RVCRN-GRCHNTPGSFRCECLPGFT-LSNDGRTC 159
+ C DVDEC++ R+C++ G C NT GS+ C+CLPGF + D + C
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVC 161
Score = 76.6 bits (180), Expect = 2e-13
Identities = 41/109 (37%), Positives = 57/109 (52%), Gaps = 14/109 (12%)
Query: 197 DINECTAVPG-ACPHGS-CENLEPGYRCICDPGYHP---------DADGLCRDIDECDMH 245
DINEC + +C S C N E Y C+C PGY P +++ C+D+DEC +
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 246 QSYCAG-GQCRNTAGSFTCVCPEGTRHEPE-LQLCRDIDEC-EGETETH 291
C G C NT GS+TC C G + PE ++C D++EC G+ H
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCH 175
Score = 70.9 bits (166), Expect = 8e-12
Identities = 58/226 (25%), Positives = 85/226 (37%), Gaps = 38/226 (16%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR---CHNTP 139
C DS C F E P T C D++EC G+ C NT
Sbjct: 33 CPQDSSCVNATACRCNPGFSSFSEIITTPMET---CDDINECATLSKVSCGKFSDCWNTE 89
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN 199
GS+ C C PG+ P G++ + +N D++
Sbjct: 90 GSYDCVCSPGYE----------------------PVSGAKTFK------NESENTCQDVD 121
Query: 200 ECTAVPGACP-HGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYC-AGGQCR 255
EC P C +G+C N Y C C PG+ P+ +C D++EC Q+ C + C
Sbjct: 122 ECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCL 181
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGD 301
N GS+ C C G + P + CEG+ ++ D + D
Sbjct: 182 NNVGSYQCRCRPGWQPIPGSPNGPNNTVCEGQELRSHVPRDPQTSD 227
Score = 56.4 bits (130), Expect = 2e-07
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 3 NGGMCTN-GICKNIDGGFECICKPGYESGSEG-ALCRDVDECRDNPRVCRRG-RCRNTAG 59
N +C + G C N G + C C PG++ E +C DV+EC C C N G
Sbjct: 126 NPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVG 185
Query: 60 SYTCLCEPGFAP 71
SY C C PG+ P
Sbjct: 186 SYQCRCRPGWQP 197
Score = 52.0 bits (119), Expect = 4e-06
Identities = 24/44 (54%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 399 KGFAKLDGATCRDVDECALSAELCAG-GTCVNTDGSYRCDCPPG 441
K F TC+DVDEC + LC GTCVNT GSY C C PG
Sbjct: 107 KTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG 150
Score = 45.6 bits (103), Expect = 4e-04
Identities = 36/122 (29%), Positives = 49/122 (40%), Gaps = 13/122 (10%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C NT G ++C C GY + A+ + +C + VD +C+ P L C S G
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC--QDVD-ECQQN-PRL------CKSYG 134
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCP 439
+ F D C DV+EC C T C+N GSY+C C
Sbjct: 135 TCVNTLGSYTCQCLPGFK--FIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCR 192
Query: 440 PG 441
PG
Sbjct: 193 PG 194
Score = 43.6 bits (98), Expect = 0.001
Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 20/108 (18%)
Query: 195 GADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL------CRDIDECDMHQS 247
GA+ + CP SC N C C+PG+ ++ + C DI+EC
Sbjct: 20 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 76
Query: 248 YCAG--GQCRNTAGSFTCVCPEG--------TRHEPELQLCRDIDECE 285
G C NT GS+ CVC G T C+D+DEC+
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 124
Score = 41.1 bits (92), Expect = 0.008
Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 2/36 (5%)
Query: 408 TCRDVDECALSAELCAG--GTCVNTDGSYRCDCPPG 441
TC D++ECA +++ G C NT+GSY C C PG
Sbjct: 64 TCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPG 99
>BC035602-1|AAH35602.2| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 103 bits (246), Expect = 2e-21
Identities = 74/250 (29%), Positives = 101/250 (40%), Gaps = 12/250 (4%)
Query: 21 CICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGY-CAD 79
C PG G +C C C G+ C C G A A G C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
Query: 80 VDECAADSMCKGGRCVNSE--GSFQCVCEAGYRPTATRGACVDVDEC-EEQRVCRNGRCH 136
+ + +C+ N + GS+ C+CE GYR A + C DVD+C E C RC
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCV 341
Query: 137 NTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGSELYAVLCPEGPSKDNGG 195
NT G F C C P + L DG + + +C+ C Y +C EG +
Sbjct: 342 NTQGGFECHCYPNYDLV-DGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHE 400
Query: 196 ADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCR 255
+ ACP N + C C GY D +C DIDEC+ + +C+ G C
Sbjct: 401 PHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGFICTDIDECE-NGGFCS-GVCH 456
Query: 256 NTAGSFTCVC 265
N G+F C+C
Sbjct: 457 NLPGTFECIC 466
Score = 87.4 bits (207), Expect = 9e-17
Identities = 75/235 (31%), Positives = 99/235 (42%), Gaps = 26/235 (11%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCRD--VDECRDNPRVCRRGRCRNT--A 58
NGG C + C I G C C G ++G C C D +C N
Sbjct: 249 NGG-CEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCND---LCEHFCVPNPDQP 303
Query: 59 GSYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
GSY+C+CE G+ A + C DVD+C + RCVN++G F+C C Y G
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNY--DLVDGE 361
Query: 118 CVD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFT-LSNDGRTCLGLKLGWGVSCQACPA 175
CV+ VD C C S+ C C GF + ++ C + ACPA
Sbjct: 362 CVEPVDPCFRAN-CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMF-----CNQTACPA 415
Query: 176 Q--GSELYAVLCPEGPSKDNGG--ADINECTAVPGACPHGSCENLEPGYRCICDP 226
+ + CPEG D+G DI+EC G C G C NL + CIC P
Sbjct: 416 DCDPNTQASCECPEGYILDDGFICTDIDECEN-GGFCS-GVCHNLPGTFECICGP 468
Score = 73.3 bits (172), Expect = 2e-12
Identities = 59/177 (33%), Positives = 71/177 (40%), Gaps = 11/177 (6%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDEC-RDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
C N GGFEC C P Y+ +G VD C R N C SY C+C GFA
Sbjct: 340 CVNTQGGFECHCYPNYDL-VDGECVEPVDPCFRAN---CEYQCQPLNQTSYLCVCAEGFA 395
Query: 71 PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVC 130
P C + C N++ S C C GY C D+DECE C
Sbjct: 396 PIPHEPHRCQMFCN-QTACPADCDPNTQAS--CECPEGYI-LDDGFICTDIDECENGGFC 451
Query: 131 RNGRCHNTPGSFRCECLPGFTL-SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCP 186
+G CHN PG+F C C P L + G C K+ G S P + L P
Sbjct: 452 -SGVCHNLPGTFECICGPDSALVRHIGTDCDSGKVDGGDSGSGEPPPSPTPGSTLTP 507
Score = 66.1 bits (154), Expect = 2e-10
Identities = 68/266 (25%), Positives = 97/266 (36%), Gaps = 58/266 (21%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG---LCRDIDEC-DMHQSYCAGGQCR 255
+C+ G C H +C + RC C G ADG C D+ + +C
Sbjct: 244 DCSVENGGCEH-ACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP-- 300
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
+ GS++C+C G R + C D+D+C E SP
Sbjct: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILE-------------------------PSP 335
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQEC 375
C RC+NT GGFEC C Y D C++ C+R + QC+ L C
Sbjct: 336 CPQ-RCVNTQGGFECHCYPNY--DLVDGECVE-PVDPCFRANCEYQCQPLNQTSYL---C 388
Query: 376 CCSVGL-----------------AWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALS 418
C+ G A + +G+ DG C D+DEC +
Sbjct: 389 VCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECE-N 447
Query: 419 AELCAGGTCVNTDGSYRCDCPPGLTL 444
C+ G C N G++ C C P L
Sbjct: 448 GGFCS-GVCHNLPGTFECICGPDSAL 472
Score = 64.9 bits (151), Expect = 6e-10
Identities = 62/217 (28%), Positives = 92/217 (42%), Gaps = 25/217 (11%)
Query: 135 CHNTPGSFRCECLPGFTLSNDGRTCLGLKL-GWGVSCQA-CPAQGSE--LYAVLCPEG-- 188
C+ PG+ RC+C G L DGR+C C+ C + Y+ +C G
Sbjct: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYR 315
Query: 189 -PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRD-IDECDMHQ 246
+ + D+++C P CP C N + G+ C C P Y DG C + +D C +
Sbjct: 316 LAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDL-VDGECVEPVDPC--FR 371
Query: 247 SYCAGGQCRN-TAGSFTCVCPEGTR---HEPE-LQLCRDIDECEGETETHYIES-DYERG 300
+ C QC+ S+ CVC EG HEP Q+ + C + + + S + G
Sbjct: 372 ANCEY-QCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEG 430
Query: 301 DIPPTFPTRTELASPCDNGR-----CINTHGGFECEC 332
I T++ C+NG C N G FEC C
Sbjct: 431 YILDDGFICTDI-DECENGGFCSGVCHNLPGTFECIC 466
Score = 54.8 bits (126), Expect = 6e-07
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 25/174 (14%)
Query: 185 CPEGPSKDNGGADINECTAVPGACPHGSCENL------EPG-YRCICDPGYHPDADG-LC 236
CP G + AD CTA + CE+ +PG Y C+C+ GY AD C
Sbjct: 267 CPAGAALQ---ADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRC 323
Query: 237 RDIDECDMHQSYCAGGQCRNTAGSFTCVC------PEGTRHEPELQLCRDIDE--CEGET 288
D+D+C + S C +C NT G F C C +G EP R E C+
Sbjct: 324 EDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLN 382
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRC---INTHGGFECECELGYVLD 339
+T Y+ E P P R ++ C+ C + + CEC GY+LD
Sbjct: 383 QTSYLCVCAEGFAPIPHEPHRCQMF--CNQTACPADCDPNTQASCECPEGYILD 434
>BC034949-1|AAH34949.1| 239|Homo sapiens EMR2 protein protein.
Length = 239
Score = 103 bits (246), Expect = 2e-21
Identities = 50/113 (44%), Positives = 68/113 (60%), Gaps = 13/113 (11%)
Query: 12 CKNIDGGFECICKPGYE--SGSEGA------LCRDVDECRDNPRVCRR-GRCRNTAGSYT 62
C N +G ++C+C PGYE SG++ C+DVDEC+ NPR+C+ G C NT GSYT
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 144
Query: 63 CLCEPG--FAPTAAGYCADVDEC-AADSMCKGG-RCVNSEGSFQCVCEAGYRP 111
C C PG F P C DV+EC + + C C+N+ GS+QC C G++P
Sbjct: 145 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQP 197
Score = 94.3 bits (224), Expect = 8e-19
Identities = 57/152 (37%), Positives = 77/152 (50%), Gaps = 23/152 (15%)
Query: 21 CICKPGYESGSE-----GALCRDVDECRDNPRV-CRR-GRCRNTAGSYTCLCEPGFAPTA 73
C C PG+ S SE C D++EC +V C + C NT GSY C+C PG+ P +
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 74 AGY---------CADVDECAADS-MCKG-GRCVNSEGSFQCVCEAGYR--PTATRGACVD 120
C DVDEC + +CK G CVN+ GS+ C C G++ P + C D
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK-VCTD 163
Query: 121 VDECEE-QRVCRNG-RCHNTPGSFRCECLPGF 150
V+EC Q C + C N GS++C C PG+
Sbjct: 164 VNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 195
Score = 84.6 bits (200), Expect = 6e-16
Identities = 46/117 (39%), Positives = 63/117 (53%), Gaps = 20/117 (17%)
Query: 63 CLCEPGFAP------TAAGYCADVDECAADSMCKGGR---CVNSEGSFQCVCEAGYRPTA 113
C C PGF+ T C D++ECA S G+ C N+EGS+ CVC GY P +
Sbjct: 45 CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
Query: 114 --------TRGACVDVDECEEQ-RVCRN-GRCHNTPGSFRCECLPGFT-LSNDGRTC 159
+ C DVDEC++ R+C++ G C NT GS+ C+CLPGF + D + C
Sbjct: 105 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVC 161
Score = 76.6 bits (180), Expect = 2e-13
Identities = 41/109 (37%), Positives = 57/109 (52%), Gaps = 14/109 (12%)
Query: 197 DINECTAVPG-ACPHGS-CENLEPGYRCICDPGYHP---------DADGLCRDIDECDMH 245
DINEC + +C S C N E Y C+C PGY P +++ C+D+DEC +
Sbjct: 67 DINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 126
Query: 246 QSYCAG-GQCRNTAGSFTCVCPEGTRHEPE-LQLCRDIDEC-EGETETH 291
C G C NT GS+TC C G + PE ++C D++EC G+ H
Sbjct: 127 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCH 175
Score = 70.9 bits (166), Expect = 8e-12
Identities = 58/226 (25%), Positives = 85/226 (37%), Gaps = 38/226 (16%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR---CHNTP 139
C DS C F E P T C D++EC G+ C NT
Sbjct: 33 CPQDSSCVNATACRCNPGFSSFSEIITTPMET---CDDINECATLSKVSCGKFSDCWNTE 89
Query: 140 GSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADIN 199
GS+ C C PG+ P G++ + +N D++
Sbjct: 90 GSYDCVCSPGYE----------------------PVSGAKTFK------NESENTCQDVD 121
Query: 200 ECTAVPGACP-HGSCENLEPGYRCICDPGYH--PDADGLCRDIDECDMHQSYC-AGGQCR 255
EC P C +G+C N Y C C PG+ P+ +C D++EC Q+ C + C
Sbjct: 122 ECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCL 181
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGD 301
N GS+ C C G + P + CEG+ ++ D + D
Sbjct: 182 NNVGSYQCRCRPGWQPIPGSPNGPNNTVCEGQELRSHVPRDPQTSD 227
Score = 56.4 bits (130), Expect = 2e-07
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 3 NGGMCTN-GICKNIDGGFECICKPGYESGSEG-ALCRDVDECRDNPRVCRRG-RCRNTAG 59
N +C + G C N G + C C PG++ E +C DV+EC C C N G
Sbjct: 126 NPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVG 185
Query: 60 SYTCLCEPGFAP 71
SY C C PG+ P
Sbjct: 186 SYQCRCRPGWQP 197
Score = 52.0 bits (119), Expect = 4e-06
Identities = 24/44 (54%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 399 KGFAKLDGATCRDVDECALSAELCAG-GTCVNTDGSYRCDCPPG 441
K F TC+DVDEC + LC GTCVNT GSY C C PG
Sbjct: 107 KTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG 150
Score = 45.6 bits (103), Expect = 4e-04
Identities = 36/122 (29%), Positives = 49/122 (40%), Gaps = 13/122 (10%)
Query: 321 CINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVG 380
C NT G ++C C GY + A+ + +C + VD +C+ P L C S G
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC--QDVD-ECQQN-PRL------CKSYG 134
Query: 381 LAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCP 439
+ F D C DV+EC C T C+N GSY+C C
Sbjct: 135 TCVNTLGSYTCQCLPGFK--FIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCR 192
Query: 440 PG 441
PG
Sbjct: 193 PG 194
Score = 43.6 bits (98), Expect = 0.001
Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 20/108 (18%)
Query: 195 GADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL------CRDIDECDMHQS 247
GA+ + CP SC N C C+PG+ ++ + C DI+EC
Sbjct: 20 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 76
Query: 248 YCAG--GQCRNTAGSFTCVCPEG--------TRHEPELQLCRDIDECE 285
G C NT GS+ CVC G T C+D+DEC+
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 124
Score = 41.1 bits (92), Expect = 0.008
Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 2/36 (5%)
Query: 408 TCRDVDECALSAELCAG--GTCVNTDGSYRCDCPPG 441
TC D++ECA +++ G C NT+GSY C C PG
Sbjct: 64 TCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPG 99
>AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitamin
B12 receptor protein.
Length = 3494
Score = 101 bits (243), Expect = 4e-21
Identities = 95/293 (32%), Positives = 125/293 (42%), Gaps = 41/293 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECR---DNPRVCRRG-RCRNTAGS 60
C NG C N+ F CIC P ++ G LC DV+EC P C+ G C NT GS
Sbjct: 12 CQNGGNCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQNGGTCVNTMGS 67
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSM--CKGGRCVN------SEGSFQCVCEAGYRP 111
Y+C C P T CA D+C S+ C G C + E + CVC+AG+
Sbjct: 68 YSCHCPP---ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMS 124
Query: 112 TATRGAC-VDVDECEEQ-RVCRN-GRCHNTPGSFRC-ECLPGFT----LSNDGRTCL--- 160
+ AC +D DEC Q C +C NT GSF C C G+ + D C
Sbjct: 125 SPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINN 184
Query: 161 -GLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINE-CTAVPGAC-PHGSCEN-L 216
G + V C P GS + CP G D + + C+ G C P SC + L
Sbjct: 185 GGCSVAPPVECVNTP--GSS-HCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTL 241
Query: 217 EPGYRCICDPGYHPDADGLCRDIDECDMHQSY-CAGGQCRNTAGSFTCVCPEG 268
C C PGY + G + ++ S+ C GQC +T + C C G
Sbjct: 242 GSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSG 294
Score = 93.1 bits (221), Expect = 2e-18
Identities = 88/287 (30%), Positives = 120/287 (41%), Gaps = 40/287 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRV-CRRGRC----RNTAG 59
C NG C N G + C C P + G C D+C C G C R AG
Sbjct: 55 CQNGGTCVNTMGSYSCHCPPE----TYGPQCASKYDDCEGGSVARCVHGICEDLMREQAG 110
Query: 60 S--YTCLCEPGF--APTAAGYCADVDECAAD-SMCKG-GRCVNSEGSFQC-VCEAGYRPT 112
Y+C+C+ G+ +P + D DEC+ C +C N++GSF C C G++
Sbjct: 111 EPKYSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGN 170
Query: 113 ATRGACVDVDECEEQR----VCRNGRCHNTPGSFRCE-CLPGFTLSNDGRTCLGLKLGWG 167
C D++ECE V C NTPGS C+ C PG+ DGR C +
Sbjct: 171 GY--ICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRVCTLTDI-CS 225
Query: 168 VS---CQACPAQGSELYAV-LCPEGPSKDNGGADINECTAVPGAC---P--HGSCENLEP 218
VS C + S L ++ LC P G N C + C P +G C +
Sbjct: 226 VSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVS 285
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
GY C CD G+ +I+EC + GG C + SF+C C
Sbjct: 286 GYFCKCDSGW--TGVNCTENINEC-LSNPCLNGGTCVDGVDSFSCEC 329
Score = 89.0 bits (211), Expect = 3e-17
Identities = 92/332 (27%), Positives = 141/332 (42%), Gaps = 53/332 (15%)
Query: 79 DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE----EQRVCRN-G 133
D C+++ GG C+N SF C+C ++ DV+ECE C+N G
Sbjct: 3 DKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPL---CSADVNECEIYSGTPLSCQNGG 59
Query: 134 RCHNTPGSFRCECLP---GFTLSNDGRTCLGLKLGWGVS--CQACPAQ--GSELYAVLCP 186
C NT GS+ C C P G ++ C G + V C+ + G Y+ +C
Sbjct: 60 TCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCD 119
Query: 187 EG-PSKDNGGA---DINECTAVPGACPH-GSCENLEPGYRC-ICDPGYHPDADGLCRDID 240
G S N A D +EC+ PG C C N + + C C G+ + +C DI+
Sbjct: 120 AGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNG-YICEDIN 178
Query: 241 ECDMHQSYCAGG---QCRNTAGSFTC-VCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
EC+++ C+ +C NT GS C CP G ++ + ++C D C + ++
Sbjct: 179 ECEINNGGCSVAPPVECVNTPGSSHCQACPPG--YQGDGRVCTLTDICSVSNGGCHPDAS 236
Query: 297 YER--GDIP--PTFPTRTE---------------LASPCDNGRCINTHGGFECECELGYV 337
G +P P T L+ PC NG+CI+T G+ C+C+ G+
Sbjct: 237 CSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWT 296
Query: 338 -LDAT--AQRCLDN---RRGSCWRRVVDGQCE 363
++ T CL N G+C V CE
Sbjct: 297 GVNCTENINECLSNPCLNGGTCVDGVDSFSCE 328
Score = 76.6 bits (180), Expect = 2e-13
Identities = 63/185 (34%), Positives = 78/185 (42%), Gaps = 23/185 (12%)
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLP---GFTLSNDGRTCLGLKLGWGVSCQ---A 172
VD C G C N SF C C P G S D C + G +SCQ
Sbjct: 2 VDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNEC-EIYSGTPLSCQNGGT 60
Query: 173 C-PAQGSELYAVLCPEGPSKDNGGADINECTAVPGA-CPHGSCENL------EPGYRCIC 224
C GS Y+ CP + ++C A C HG CE+L EP Y C+C
Sbjct: 61 CVNTMGS--YSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVC 118
Query: 225 DPGY--HPDADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTC-VCPEGTRHEPELQLCRD 280
D G+ P++ D DEC C+ QC NT GSF C CP G + +C D
Sbjct: 119 DAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNG--YICED 176
Query: 281 IDECE 285
I+ECE
Sbjct: 177 INECE 181
Score = 64.1 bits (149), Expect = 1e-09
Identities = 47/157 (29%), Positives = 66/157 (42%), Gaps = 13/157 (8%)
Query: 5 GMCTNGI-CKNIDGGFEC-ICKPGYESGSEGALCRDVDECRDNPRVCRRG---RCRNTAG 59
G C+ + C N G F C C G++ G +C D++EC N C C NT G
Sbjct: 143 GPCSTLVQCFNTQGSFYCGACPTGWQGN--GYICEDINECEINNGGCSVAPPVECVNTPG 200
Query: 60 SYTC-LCEPGFAPTAAGYCADVDECA-ADSMCK-GGRCVNSEGSFQ-CVCEAGYRPTATR 115
S C C PG+ C D C+ ++ C C ++ GS C C GY
Sbjct: 201 SSHCQACPPGYQGDGR-VCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYG 259
Query: 116 -GACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT 151
CV + C NG+C +T + C+C G+T
Sbjct: 260 PNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWT 296
Score = 61.3 bits (142), Expect = 7e-09
Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 7/108 (6%)
Query: 1 MTNGGMCTNGICKNIDGGFE-CICKPGYESGSEGAL-CRDVDE-CRDNPRVCRRGRCRNT 57
++NGG + C + G C C PGY G C + C +P C G+C +T
Sbjct: 226 VSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHP--CLNGQCIDT 283
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVC 105
Y C C+ G+ T +++EC ++ GG CV+ SF C C
Sbjct: 284 VSGYFCKCDSGW--TGVNCTENINECLSNPCLNGGTCVDGVDSFSCEC 329
Score = 40.3 bits (90), Expect = 0.014
Identities = 21/40 (52%), Positives = 24/40 (60%), Gaps = 5/40 (12%)
Query: 406 GATCR-DVDECALSAEL---CA-GGTCVNTDGSYRCDCPP 440
G C DV+EC + + C GGTCVNT GSY C CPP
Sbjct: 35 GPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPP 74
Score = 39.9 bits (89), Expect = 0.018
Identities = 55/210 (26%), Positives = 79/210 (37%), Gaps = 33/210 (15%)
Query: 251 GGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDECEGETETHYIESDYERGDIPPTFPTR 309
GG C N SF C+CP + LC D++ECE + T S G T +
Sbjct: 15 GGNCLNLHDSFFCICPPQWKGP----LCSADVNECEIYSGTPL--SCQNGGTCVNTMGSY 68
Query: 310 TELASPCDNG-RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAA--- 365
+ P G +C + + +CE G V C D R C+A
Sbjct: 69 SCHCPPETYGPQCASKYD----DCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMS 124
Query: 366 ---APELLL-RQEC------CCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDEC 415
+P L R EC C ++ + + +G +G C D++EC
Sbjct: 125 SPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQG----NGYICEDINEC 180
Query: 416 ALSAELCAGG---TCVNTDGSYRCD-CPPG 441
++ C+ CVNT GS C CPPG
Sbjct: 181 EINNGGCSVAPPVECVNTPGSSHCQACPPG 210
>AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12
receptor precursor protein.
Length = 3623
Score = 101 bits (243), Expect = 4e-21
Identities = 95/293 (32%), Positives = 125/293 (42%), Gaps = 41/293 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECR---DNPRVCRRG-RCRNTAGS 60
C NG C N+ F CIC P ++ G LC DV+EC P C+ G C NT GS
Sbjct: 141 CQNGGNCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQNGGTCVNTMGS 196
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSM--CKGGRCVN------SEGSFQCVCEAGYRP 111
Y+C C P T CA D+C S+ C G C + E + CVC+AG+
Sbjct: 197 YSCHCPP---ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMS 253
Query: 112 TATRGAC-VDVDECEEQ-RVCRN-GRCHNTPGSFRC-ECLPGFT----LSNDGRTCL--- 160
+ AC +D DEC Q C +C NT GSF C C G+ + D C
Sbjct: 254 SPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINN 313
Query: 161 -GLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINE-CTAVPGAC-PHGSCEN-L 216
G + V C P GS + CP G D + + C+ G C P SC + L
Sbjct: 314 GGCSVAPPVECVNTP--GSS-HCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTL 370
Query: 217 EPGYRCICDPGYHPDADGLCRDIDECDMHQSY-CAGGQCRNTAGSFTCVCPEG 268
C C PGY + G + ++ S+ C GQC +T + C C G
Sbjct: 371 GSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSG 423
Score = 93.1 bits (221), Expect = 2e-18
Identities = 88/287 (30%), Positives = 120/287 (41%), Gaps = 40/287 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRV-CRRGRC----RNTAG 59
C NG C N G + C C P + G C D+C C G C R AG
Sbjct: 184 CQNGGTCVNTMGSYSCHCPPE----TYGPQCASKYDDCEGGSVARCVHGICEDLMREQAG 239
Query: 60 S--YTCLCEPGF--APTAAGYCADVDECAAD-SMCKG-GRCVNSEGSFQC-VCEAGYRPT 112
Y+C+C+ G+ +P + D DEC+ C +C N++GSF C C G++
Sbjct: 240 EPKYSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGN 299
Query: 113 ATRGACVDVDECEEQR----VCRNGRCHNTPGSFRCE-CLPGFTLSNDGRTCLGLKLGWG 167
C D++ECE V C NTPGS C+ C PG+ DGR C +
Sbjct: 300 GY--ICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRVCTLTDI-CS 354
Query: 168 VS---CQACPAQGSELYAV-LCPEGPSKDNGGADINECTAVPGAC---P--HGSCENLEP 218
VS C + S L ++ LC P G N C + C P +G C +
Sbjct: 355 VSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVS 414
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
GY C CD G+ +I+EC + GG C + SF+C C
Sbjct: 415 GYFCKCDSGW--TGVNCTENINEC-LSNPCLNGGTCVDGVDSFSCEC 458
Score = 89.0 bits (211), Expect = 3e-17
Identities = 92/332 (27%), Positives = 141/332 (42%), Gaps = 53/332 (15%)
Query: 79 DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE----EQRVCRN-G 133
D C+++ GG C+N SF C+C ++ DV+ECE C+N G
Sbjct: 132 DKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPL---CSADVNECEIYSGTPLSCQNGG 188
Query: 134 RCHNTPGSFRCECLP---GFTLSNDGRTCLGLKLGWGVS--CQACPAQ--GSELYAVLCP 186
C NT GS+ C C P G ++ C G + V C+ + G Y+ +C
Sbjct: 189 TCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCD 248
Query: 187 EG-PSKDNGGA---DINECTAVPGACPH-GSCENLEPGYRC-ICDPGYHPDADGLCRDID 240
G S N A D +EC+ PG C C N + + C C G+ + +C DI+
Sbjct: 249 AGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNG-YICEDIN 307
Query: 241 ECDMHQSYCAGG---QCRNTAGSFTC-VCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
EC+++ C+ +C NT GS C CP G ++ + ++C D C + ++
Sbjct: 308 ECEINNGGCSVAPPVECVNTPGSSHCQACPPG--YQGDGRVCTLTDICSVSNGGCHPDAS 365
Query: 297 YER--GDIP--PTFPTRTE---------------LASPCDNGRCINTHGGFECECELGYV 337
G +P P T L+ PC NG+CI+T G+ C+C+ G+
Sbjct: 366 CSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWT 425
Query: 338 -LDAT--AQRCLDN---RRGSCWRRVVDGQCE 363
++ T CL N G+C V CE
Sbjct: 426 GVNCTENINECLSNPCLNGGTCVDGVDSFSCE 457
Score = 76.6 bits (180), Expect = 2e-13
Identities = 63/185 (34%), Positives = 78/185 (42%), Gaps = 23/185 (12%)
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLP---GFTLSNDGRTCLGLKLGWGVSCQ---A 172
VD C G C N SF C C P G S D C + G +SCQ
Sbjct: 131 VDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNEC-EIYSGTPLSCQNGGT 189
Query: 173 C-PAQGSELYAVLCPEGPSKDNGGADINECTAVPGA-CPHGSCENL------EPGYRCIC 224
C GS Y+ CP + ++C A C HG CE+L EP Y C+C
Sbjct: 190 CVNTMGS--YSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVC 247
Query: 225 DPGY--HPDADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTC-VCPEGTRHEPELQLCRD 280
D G+ P++ D DEC C+ QC NT GSF C CP G + +C D
Sbjct: 248 DAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNG--YICED 305
Query: 281 IDECE 285
I+ECE
Sbjct: 306 INECE 310
Score = 64.1 bits (149), Expect = 1e-09
Identities = 47/157 (29%), Positives = 66/157 (42%), Gaps = 13/157 (8%)
Query: 5 GMCTNGI-CKNIDGGFEC-ICKPGYESGSEGALCRDVDECRDNPRVCRRG---RCRNTAG 59
G C+ + C N G F C C G++ G +C D++EC N C C NT G
Sbjct: 272 GPCSTLVQCFNTQGSFYCGACPTGWQGN--GYICEDINECEINNGGCSVAPPVECVNTPG 329
Query: 60 SYTC-LCEPGFAPTAAGYCADVDECA-ADSMCK-GGRCVNSEGSFQ-CVCEAGYRPTATR 115
S C C PG+ C D C+ ++ C C ++ GS C C GY
Sbjct: 330 SSHCQACPPGYQGDGR-VCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYG 388
Query: 116 -GACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT 151
CV + C NG+C +T + C+C G+T
Sbjct: 389 PNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWT 425
Score = 61.3 bits (142), Expect = 7e-09
Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 7/108 (6%)
Query: 1 MTNGGMCTNGICKNIDGGFE-CICKPGYESGSEGAL-CRDVDE-CRDNPRVCRRGRCRNT 57
++NGG + C + G C C PGY G C + C +P C G+C +T
Sbjct: 355 VSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHP--CLNGQCIDT 412
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVC 105
Y C C+ G+ T +++EC ++ GG CV+ SF C C
Sbjct: 413 VSGYFCKCDSGW--TGVNCTENINECLSNPCLNGGTCVDGVDSFSCEC 458
Score = 41.5 bits (93), Expect = 0.006
Identities = 59/228 (25%), Positives = 87/228 (38%), Gaps = 34/228 (14%)
Query: 234 GLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDECEGETETH 291
GL + +D+ + C GG C N SF C+CP + LC D++ECE + T
Sbjct: 126 GLQQTVDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGP----LCSADVNECEIYSGTP 181
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLDATAQRCLDNRR 350
S G T + + P G +C + + +CE G V C D R
Sbjct: 182 L--SCQNGGTCVNTMGSYSCHCPPETYGPQCASKYD----DCEGGSVARCVHGICEDLMR 235
Query: 351 GSCWRRVVDGQCEAA------APELLL-RQEC------CCSVGLAWGSXXXXXXXXXXXX 397
C+A +P L R EC C ++ + +
Sbjct: 236 EQAGEPKYSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTG 295
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGG---TCVNTDGSYRCD-CPPG 441
+G +G C D++EC ++ C+ CVNT GS C CPPG
Sbjct: 296 WQG----NGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPG 339
>AB209121-1|BAD92358.1| 620|Homo sapiens Mutant p53 binding protein
1 variant protein.
Length = 620
Score = 101 bits (243), Expect = 4e-21
Identities = 77/220 (35%), Positives = 101/220 (45%), Gaps = 21/220 (9%)
Query: 79 DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNT 138
D+DEC C+ RCVN GSF+C CE G++ +CVDV+EC+ C RC N+
Sbjct: 254 DIDECRY-RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQ-RCFNS 310
Query: 139 PGSFRCECLPGFTLSNDGRTCLGLK----LGWGVSCQA----CPAQGSELY--AVLCPEG 188
G+F C C G+ L DG +C G + V QA C S + + C
Sbjct: 311 YGTFLCRCHQGYELHRDGFSCSGESSIPAVYSSVDPQALAMPCLLPHSSPFEASASCHCA 370
Query: 189 PSKDNGGAD---INECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
PS G + A G GS E + G HP A DIDEC +
Sbjct: 371 PSCLLGTRPRLAVEHSQASGGGTRRGSYVLTEAYWGMPLTRGPHPHASS---DIDECS-Y 426
Query: 246 QSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECE 285
SY +C N G F+C CP+G + +LC+DIDECE
Sbjct: 427 SSYLCQYRCVNEPGRFSCHCPQGYQ-LLATRLCQDIDECE 465
Score = 99.5 bits (237), Expect = 2e-20
Identities = 80/245 (32%), Positives = 102/245 (41%), Gaps = 23/245 (9%)
Query: 35 LCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF--APTAAGYCADVDECAADSMCKGG 92
L D+DECR R C+ RC N GS+ C CEPGF P C DV+EC + C+
Sbjct: 251 LSLDIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRS-CVDVNECDMGAPCE-Q 305
Query: 93 RCVNSEGSFQCVCEAGYRPTATRGAC----------VDVDECEEQRVCRNGRCHNTPGSF 142
RC NS G+F C C GY +C VD C S
Sbjct: 306 RCFNSYGTFLCRCHQGYELHRDGFSCSGESSIPAVYSSVDPQALAMPCLLPHSSPFEASA 365
Query: 143 RCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELY-AVLCPEGPSKDNGGADINEC 201
C C P L R + G + +E Y + GP + +DI+EC
Sbjct: 366 SCHCAPSCLLGTRPRLAVEHSQASGGGTRRGSYVLTEAYWGMPLTRGP-HPHASSDIDEC 424
Query: 202 TAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAG 259
+ C + C N EPG + C C GY A LC+DIDEC+ C+ Q C N G
Sbjct: 425 SYSSYLCQY-RCVN-EPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHG 482
Query: 260 SFTCV 264
+ CV
Sbjct: 483 GYRCV 487
Score = 64.1 bits (149), Expect = 1e-09
Identities = 71/257 (27%), Positives = 101/257 (39%), Gaps = 41/257 (15%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCR 255
DI+EC C H C NL +RC C+PG+ + C D++ECDM + C +C
Sbjct: 254 DIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM-GAPCE-QRCF 308
Query: 256 NTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASP 315
N+ G+F C C +G +L RD C GE+ + S + P LA P
Sbjct: 309 NSYGTFLCRCHQG------YELHRDGFSCSGESSIPAVYS-----SVDP-----QALAMP 352
Query: 316 CDNGRCINTHGGFECECELGYVLDATAQRCLDN--------RRGS------CW-RRVVDG 360
C C C +L + +++ RRGS W + G
Sbjct: 353 CLLPHSSPFEASASCHCAPSCLLGTRPRLAVEHSQASGGGTRRGSYVLTEAYWGMPLTRG 412
Query: 361 QCEAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAE 420
A+ ++ EC S L +G+ L C+D+DEC A
Sbjct: 413 PHPHASSDI---DECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAH 469
Query: 421 LCA-GGTCVNTDGSYRC 436
C+ TCVN G YRC
Sbjct: 470 QCSEAQTCVNFHGGYRC 486
Score = 60.5 bits (140), Expect = 1e-08
Identities = 43/126 (34%), Positives = 56/126 (44%), Gaps = 8/126 (6%)
Query: 21 CICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCADV 80
C C P G+ L V+ + + RRG T + G P A+ +D+
Sbjct: 367 CHCAPSCLLGTRPRLA--VEHSQASGGGTRRGSYVLTEAYWGMPLTRGPHPHAS---SDI 421
Query: 81 DECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVCRNGR-CHNT 138
DEC+ S RCVN G F C C GY+ ATR C D+DECE C + C N
Sbjct: 422 DECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATR-LCQDIDECESGAHQCSEAQTCVNF 480
Query: 139 PGSFRC 144
G +RC
Sbjct: 481 HGGYRC 486
Score = 55.2 bits (127), Expect = 5e-07
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
C N+ G F C C+PG++ G C DV+EC D C + RC N+ G++ C C G+
Sbjct: 267 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNEC-DMGAPCEQ-RCFNSYGTFLCRCHQGY 322
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/111 (30%), Positives = 45/111 (40%), Gaps = 30/111 (27%)
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETHYIE 294
L DIDEC YC +C N GSF C C G + P + C D++EC+
Sbjct: 251 LSLDIDEC--RYRYCQH-RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECD--------- 298
Query: 295 SDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
+ +PC+ RC N++G F C C GY L C
Sbjct: 299 -----------------MGAPCEQ-RCFNSYGTFLCRCHQGYELHRDGFSC 331
Score = 43.2 bits (97), Expect = 0.002
Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCL 64
C N G F C C GY+ + LC+D+DEC C + C N G Y C+
Sbjct: 435 CVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTCVNFHGGYRCV 487
Score = 38.7 bits (86), Expect = 0.042
Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Query: 411 DVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDST 447
D+DEC+ S+ LC CVN G + C CP G L +T
Sbjct: 420 DIDECSYSSYLCQY-RCVNEPGRFSCHCPQGYQLLAT 455
Score = 34.3 bits (75), Expect = 0.90
Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 3/34 (8%)
Query: 411 DVDECALSAELCAGGTCVNTDGSYRCDCPPGLTL 444
D+DEC C CVN GS+RC C PG L
Sbjct: 254 DIDECRY--RYCQH-RCVNLPGSFRCQCEPGFQL 284
>AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 101 bits (242), Expect = 5e-21
Identities = 95/293 (32%), Positives = 125/293 (42%), Gaps = 41/293 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECR---DNPRVCRRG-RCRNTAGS 60
C NG C N+ F CIC P ++ G LC DV+EC P C+ G C NT GS
Sbjct: 141 CQNGGTCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQNGGTCVNTMGS 196
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSM--CKGGRCVN------SEGSFQCVCEAGYRP 111
Y+C C P T CA D+C S+ C G C + E + CVC+AG+
Sbjct: 197 YSCHCPP---ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMF 253
Query: 112 TATRGAC-VDVDECEEQ-RVCRN-GRCHNTPGSFRC-ECLPGFT----LSNDGRTCL--- 160
+ AC +D DEC Q C +C NT GSF C C G+ + D C
Sbjct: 254 SPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINN 313
Query: 161 -GLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINE-CTAVPGAC-PHGSCEN-L 216
G + V C P GS + CP G D + + C+ G C P SC + L
Sbjct: 314 GGCSVAPPVECVNTP--GSS-HCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTL 370
Query: 217 EPGYRCICDPGYHPDADGLCRDIDECDMHQSY-CAGGQCRNTAGSFTCVCPEG 268
C C PGY + G + ++ S+ C GQC +T + C C G
Sbjct: 371 GSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSG 423
Score = 95.1 bits (226), Expect = 5e-19
Identities = 89/287 (31%), Positives = 120/287 (41%), Gaps = 40/287 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRV-CRRGRC----RNTAG 59
C NG C N G + C C P + G C D+C C G C R AG
Sbjct: 184 CQNGGTCVNTMGSYSCHCPPE----TYGPQCASKYDDCEGGSVARCVHGICEDLMREQAG 239
Query: 60 S--YTCLCEPG--FAPTAAGYCADVDECAAD-SMCKG-GRCVNSEGSFQC-VCEAGYRPT 112
Y+C+C+ G F+P + D DEC+ C +C N++GSF C C G++
Sbjct: 240 EPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGN 299
Query: 113 ATRGACVDVDECEEQR----VCRNGRCHNTPGSFRCE-CLPGFTLSNDGRTCLGLKLGWG 167
C D++ECE V C NTPGS C+ C PG+ DGR C +
Sbjct: 300 GY--ICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRVCTLTDI-CS 354
Query: 168 VS---CQACPAQGSELYAV-LCPEGPSKDNGGADINECTAVPGAC---P--HGSCENLEP 218
VS C + S L ++ LC P G N C + C P +G C +
Sbjct: 355 VSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVS 414
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
GY C CD G+ +I+EC + GG C + SF+C C
Sbjct: 415 GYFCKCDSGW--TGVNCTENINEC-LSNPCLNGGTCVDGVDSFSCEC 458
Score = 88.2 bits (209), Expect = 5e-17
Identities = 90/332 (27%), Positives = 140/332 (42%), Gaps = 53/332 (15%)
Query: 79 DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE----EQRVCRN-G 133
D C+++ GG C+N SF C+C ++ DV+ECE C+N G
Sbjct: 132 DKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPL---CSADVNECEIYSGTPLSCQNGG 188
Query: 134 RCHNTPGSFRCECLP---GFTLSNDGRTCLGLKLGWGVS--CQACPAQ--GSELYAVLCP 186
C NT GS+ C C P G ++ C G + V C+ + G Y+ +C
Sbjct: 189 TCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCD 248
Query: 187 EG----PSKDNGGADINECTAVPGACPH-GSCENLEPGYRC-ICDPGYHPDADGLCRDID 240
G P+ D +EC+ PG C C N + + C C G+ + +C DI+
Sbjct: 249 AGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNG-YICEDIN 307
Query: 241 ECDMHQSYCAGG---QCRNTAGSFTC-VCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
EC+++ C+ +C NT GS C CP G ++ + ++C D C + ++
Sbjct: 308 ECEINNGGCSVAPPVECVNTPGSSHCQACPPG--YQGDGRVCTLTDICSVSNGGCHPDAS 365
Query: 297 YER--GDIP--PTFPTRTE---------------LASPCDNGRCINTHGGFECECELGYV 337
G +P P T L+ PC NG+CI+T G+ C+C+ G+
Sbjct: 366 CSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWT 425
Query: 338 -LDAT--AQRCLDN---RRGSCWRRVVDGQCE 363
++ T CL N G+C V CE
Sbjct: 426 GVNCTENINECLSNPCLNGGTCVDGVDSFSCE 457
Score = 76.6 bits (180), Expect = 2e-13
Identities = 63/185 (34%), Positives = 78/185 (42%), Gaps = 23/185 (12%)
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLP---GFTLSNDGRTCLGLKLGWGVSCQ---A 172
VD C G C N SF C C P G S D C + G +SCQ
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNEC-EIYSGTPLSCQNGGT 189
Query: 173 C-PAQGSELYAVLCPEGPSKDNGGADINECTAVPGA-CPHGSCENL------EPGYRCIC 224
C GS Y+ CP + ++C A C HG CE+L EP Y C+C
Sbjct: 190 CVNTMGS--YSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVC 247
Query: 225 DPG--YHPDADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTC-VCPEGTRHEPELQLCRD 280
D G + P++ D DEC C+ QC NT GSF C CP G + +C D
Sbjct: 248 DAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNG--YICED 305
Query: 281 IDECE 285
I+ECE
Sbjct: 306 INECE 310
Score = 64.1 bits (149), Expect = 1e-09
Identities = 47/157 (29%), Positives = 66/157 (42%), Gaps = 13/157 (8%)
Query: 5 GMCTNGI-CKNIDGGFEC-ICKPGYESGSEGALCRDVDECRDNPRVCRRG---RCRNTAG 59
G C+ + C N G F C C G++ G +C D++EC N C C NT G
Sbjct: 272 GPCSTLVQCFNTQGSFYCGACPTGWQGN--GYICEDINECEINNGGCSVAPPVECVNTPG 329
Query: 60 SYTC-LCEPGFAPTAAGYCADVDECA-ADSMCK-GGRCVNSEGSFQ-CVCEAGYRPTATR 115
S C C PG+ C D C+ ++ C C ++ GS C C GY
Sbjct: 330 SSHCQACPPGYQGDGR-VCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYG 388
Query: 116 -GACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT 151
CV + C NG+C +T + C+C G+T
Sbjct: 389 PNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWT 425
Score = 61.3 bits (142), Expect = 7e-09
Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 7/108 (6%)
Query: 1 MTNGGMCTNGICKNIDGGFE-CICKPGYESGSEGAL-CRDVDE-CRDNPRVCRRGRCRNT 57
++NGG + C + G C C PGY G C + C +P C G+C +T
Sbjct: 355 VSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHP--CLNGQCIDT 412
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVC 105
Y C C+ G+ T +++EC ++ GG CV+ SF C C
Sbjct: 413 VSGYFCKCDSGW--TGVNCTENINECLSNPCLNGGTCVDGVDSFSCEC 458
Score = 41.1 bits (92), Expect = 0.008
Identities = 59/228 (25%), Positives = 87/228 (38%), Gaps = 34/228 (14%)
Query: 234 GLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDECEGETETH 291
GL + +D+ + C GG C N SF C+CP + LC D++ECE + T
Sbjct: 126 GLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGP----LCSADVNECEIYSGTP 181
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLDATAQRCLDNRR 350
S G T + + P G +C + + +CE G V C D R
Sbjct: 182 L--SCQNGGTCVNTMGSYSCHCPPETYGPQCASKYD----DCEGGSVARCVHGICEDLMR 235
Query: 351 GSCWRRVVDGQCEAA------APELLL-RQEC------CCSVGLAWGSXXXXXXXXXXXX 397
C+A +P L R EC C ++ + +
Sbjct: 236 EQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTG 295
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGG---TCVNTDGSYRCD-CPPG 441
+G +G C D++EC ++ C+ CVNT GS C CPPG
Sbjct: 296 WQG----NGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPG 339
>AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 101 bits (242), Expect = 5e-21
Identities = 95/293 (32%), Positives = 125/293 (42%), Gaps = 41/293 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECR---DNPRVCRRG-RCRNTAGS 60
C NG C N+ F CIC P ++ G LC DV+EC P C+ G C NT GS
Sbjct: 141 CQNGGTCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQNGGTCVNTMGS 196
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSM--CKGGRCVN------SEGSFQCVCEAGYRP 111
Y+C C P T CA D+C S+ C G C + E + CVC+AG+
Sbjct: 197 YSCHCPP---ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMF 253
Query: 112 TATRGAC-VDVDECEEQ-RVCRN-GRCHNTPGSFRC-ECLPGFT----LSNDGRTCL--- 160
+ AC +D DEC Q C +C NT GSF C C G+ + D C
Sbjct: 254 SPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINN 313
Query: 161 -GLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINE-CTAVPGAC-PHGSCEN-L 216
G + V C P GS + CP G D + + C+ G C P SC + L
Sbjct: 314 GGCSVAPPVECVNTP--GSS-HCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTL 370
Query: 217 EPGYRCICDPGYHPDADGLCRDIDECDMHQSY-CAGGQCRNTAGSFTCVCPEG 268
C C PGY + G + ++ S+ C GQC +T + C C G
Sbjct: 371 GSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSG 423
Score = 95.1 bits (226), Expect = 5e-19
Identities = 89/287 (31%), Positives = 120/287 (41%), Gaps = 40/287 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRV-CRRGRC----RNTAG 59
C NG C N G + C C P + G C D+C C G C R AG
Sbjct: 184 CQNGGTCVNTMGSYSCHCPPE----TYGPQCASKYDDCEGGSVARCVHGICEDLMREQAG 239
Query: 60 S--YTCLCEPG--FAPTAAGYCADVDECAAD-SMCKG-GRCVNSEGSFQC-VCEAGYRPT 112
Y+C+C+ G F+P + D DEC+ C +C N++GSF C C G++
Sbjct: 240 EPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGN 299
Query: 113 ATRGACVDVDECEEQR----VCRNGRCHNTPGSFRCE-CLPGFTLSNDGRTCLGLKLGWG 167
C D++ECE V C NTPGS C+ C PG+ DGR C +
Sbjct: 300 GY--ICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRVCTLTDI-CS 354
Query: 168 VS---CQACPAQGSELYAV-LCPEGPSKDNGGADINECTAVPGAC---P--HGSCENLEP 218
VS C + S L ++ LC P G N C + C P +G C +
Sbjct: 355 VSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVS 414
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
GY C CD G+ +I+EC + GG C + SF+C C
Sbjct: 415 GYFCKCDSGW--TGVNCTENINEC-LSNPCLNGGTCVDGVDSFSCEC 458
Score = 88.2 bits (209), Expect = 5e-17
Identities = 90/332 (27%), Positives = 140/332 (42%), Gaps = 53/332 (15%)
Query: 79 DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE----EQRVCRN-G 133
D C+++ GG C+N SF C+C ++ DV+ECE C+N G
Sbjct: 132 DKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPL---CSADVNECEIYSGTPLSCQNGG 188
Query: 134 RCHNTPGSFRCECLP---GFTLSNDGRTCLGLKLGWGVS--CQACPAQ--GSELYAVLCP 186
C NT GS+ C C P G ++ C G + V C+ + G Y+ +C
Sbjct: 189 TCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCD 248
Query: 187 EG----PSKDNGGADINECTAVPGACPH-GSCENLEPGYRC-ICDPGYHPDADGLCRDID 240
G P+ D +EC+ PG C C N + + C C G+ + +C DI+
Sbjct: 249 AGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNG-YICEDIN 307
Query: 241 ECDMHQSYCAGG---QCRNTAGSFTC-VCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
EC+++ C+ +C NT GS C CP G ++ + ++C D C + ++
Sbjct: 308 ECEINNGGCSVAPPVECVNTPGSSHCQACPPG--YQGDGRVCTLTDICSVSNGGCHPDAS 365
Query: 297 YER--GDIP--PTFPTRTE---------------LASPCDNGRCINTHGGFECECELGYV 337
G +P P T L+ PC NG+CI+T G+ C+C+ G+
Sbjct: 366 CSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWT 425
Query: 338 -LDAT--AQRCLDN---RRGSCWRRVVDGQCE 363
++ T CL N G+C V CE
Sbjct: 426 GVNCTENINECLSNPCLNGGTCVDGVDSFSCE 457
Score = 76.6 bits (180), Expect = 2e-13
Identities = 63/185 (34%), Positives = 78/185 (42%), Gaps = 23/185 (12%)
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLP---GFTLSNDGRTCLGLKLGWGVSCQ---A 172
VD C G C N SF C C P G S D C + G +SCQ
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNEC-EIYSGTPLSCQNGGT 189
Query: 173 C-PAQGSELYAVLCPEGPSKDNGGADINECTAVPGA-CPHGSCENL------EPGYRCIC 224
C GS Y+ CP + ++C A C HG CE+L EP Y C+C
Sbjct: 190 CVNTMGS--YSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVC 247
Query: 225 DPG--YHPDADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTC-VCPEGTRHEPELQLCRD 280
D G + P++ D DEC C+ QC NT GSF C CP G + +C D
Sbjct: 248 DAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNG--YICED 305
Query: 281 IDECE 285
I+ECE
Sbjct: 306 INECE 310
Score = 64.1 bits (149), Expect = 1e-09
Identities = 47/157 (29%), Positives = 66/157 (42%), Gaps = 13/157 (8%)
Query: 5 GMCTNGI-CKNIDGGFEC-ICKPGYESGSEGALCRDVDECRDNPRVCRRG---RCRNTAG 59
G C+ + C N G F C C G++ G +C D++EC N C C NT G
Sbjct: 272 GPCSTLVQCFNTQGSFYCGACPTGWQGN--GYICEDINECEINNGGCSVAPPVECVNTPG 329
Query: 60 SYTC-LCEPGFAPTAAGYCADVDECA-ADSMCK-GGRCVNSEGSFQ-CVCEAGYRPTATR 115
S C C PG+ C D C+ ++ C C ++ GS C C GY
Sbjct: 330 SSHCQACPPGYQGDGR-VCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYG 388
Query: 116 -GACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT 151
CV + C NG+C +T + C+C G+T
Sbjct: 389 PNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWT 425
Score = 61.3 bits (142), Expect = 7e-09
Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 7/108 (6%)
Query: 1 MTNGGMCTNGICKNIDGGFE-CICKPGYESGSEGAL-CRDVDE-CRDNPRVCRRGRCRNT 57
++NGG + C + G C C PGY G C + C +P C G+C +T
Sbjct: 355 VSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHP--CLNGQCIDT 412
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVC 105
Y C C+ G+ T +++EC ++ GG CV+ SF C C
Sbjct: 413 VSGYFCKCDSGW--TGVNCTENINECLSNPCLNGGTCVDGVDSFSCEC 458
Score = 41.1 bits (92), Expect = 0.008
Identities = 59/228 (25%), Positives = 87/228 (38%), Gaps = 34/228 (14%)
Query: 234 GLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDECEGETETH 291
GL + +D+ + C GG C N SF C+CP + LC D++ECE + T
Sbjct: 126 GLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGP----LCSADVNECEIYSGTP 181
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLDATAQRCLDNRR 350
S G T + + P G +C + + +CE G V C D R
Sbjct: 182 L--SCQNGGTCVNTMGSYSCHCPPETYGPQCASKYD----DCEGGSVARCVHGICEDLMR 235
Query: 351 GSCWRRVVDGQCEAA------APELLL-RQEC------CCSVGLAWGSXXXXXXXXXXXX 397
C+A +P L R EC C ++ + +
Sbjct: 236 EQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTG 295
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGG---TCVNTDGSYRCD-CPPG 441
+G +G C D++EC ++ C+ CVNT GS C CPPG
Sbjct: 296 WQG----NGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPG 339
>AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 101 bits (242), Expect = 5e-21
Identities = 95/293 (32%), Positives = 125/293 (42%), Gaps = 41/293 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCR-DVDECR---DNPRVCRRG-RCRNTAGS 60
C NG C N+ F CIC P ++ G LC DV+EC P C+ G C NT GS
Sbjct: 141 CQNGGTCLNLHDSFFCICPPQWK----GPLCSADVNECEIYSGTPLSCQNGGTCVNTMGS 196
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSM--CKGGRCVN------SEGSFQCVCEAGYRP 111
Y+C C P T CA D+C S+ C G C + E + CVC+AG+
Sbjct: 197 YSCHCPP---ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMF 253
Query: 112 TATRGAC-VDVDECEEQ-RVCRN-GRCHNTPGSFRC-ECLPGFT----LSNDGRTCL--- 160
+ AC +D DEC Q C +C NT GSF C C G+ + D C
Sbjct: 254 SPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINN 313
Query: 161 -GLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINE-CTAVPGAC-PHGSCEN-L 216
G + V C P GS + CP G D + + C+ G C P SC + L
Sbjct: 314 GGCSVAPPVECVNTP--GSS-HCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTL 370
Query: 217 EPGYRCICDPGYHPDADGLCRDIDECDMHQSY-CAGGQCRNTAGSFTCVCPEG 268
C C PGY + G + ++ S+ C GQC +T + C C G
Sbjct: 371 GSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSG 423
Score = 95.1 bits (226), Expect = 5e-19
Identities = 89/287 (31%), Positives = 120/287 (41%), Gaps = 40/287 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRV-CRRGRC----RNTAG 59
C NG C N G + C C P + G C D+C C G C R AG
Sbjct: 184 CQNGGTCVNTMGSYSCHCPPE----TYGPQCASKYDDCEGGSVARCVHGICEDLMREQAG 239
Query: 60 S--YTCLCEPG--FAPTAAGYCADVDECAAD-SMCKG-GRCVNSEGSFQC-VCEAGYRPT 112
Y+C+C+ G F+P + D DEC+ C +C N++GSF C C G++
Sbjct: 240 EPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGN 299
Query: 113 ATRGACVDVDECEEQR----VCRNGRCHNTPGSFRCE-CLPGFTLSNDGRTCLGLKLGWG 167
C D++ECE V C NTPGS C+ C PG+ DGR C +
Sbjct: 300 GY--ICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY--QGDGRVCTLTDI-CS 354
Query: 168 VS---CQACPAQGSELYAV-LCPEGPSKDNGGADINECTAVPGAC---P--HGSCENLEP 218
VS C + S L ++ LC P G N C + C P +G C +
Sbjct: 355 VSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVS 414
Query: 219 GYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
GY C CD G+ +I+EC + GG C + SF+C C
Sbjct: 415 GYFCKCDSGW--TGVNCTENINEC-LSNPCLNGGTCVDGVDSFSCEC 458
Score = 88.2 bits (209), Expect = 5e-17
Identities = 90/332 (27%), Positives = 140/332 (42%), Gaps = 53/332 (15%)
Query: 79 DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE----EQRVCRN-G 133
D C+++ GG C+N SF C+C ++ DV+ECE C+N G
Sbjct: 132 DKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPL---CSADVNECEIYSGTPLSCQNGG 188
Query: 134 RCHNTPGSFRCECLP---GFTLSNDGRTCLGLKLGWGVS--CQACPAQ--GSELYAVLCP 186
C NT GS+ C C P G ++ C G + V C+ + G Y+ +C
Sbjct: 189 TCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCD 248
Query: 187 EG----PSKDNGGADINECTAVPGACPH-GSCENLEPGYRC-ICDPGYHPDADGLCRDID 240
G P+ D +EC+ PG C C N + + C C G+ + +C DI+
Sbjct: 249 AGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNG-YICEDIN 307
Query: 241 ECDMHQSYCAGG---QCRNTAGSFTC-VCPEGTRHEPELQLCRDIDECEGETETHYIESD 296
EC+++ C+ +C NT GS C CP G ++ + ++C D C + ++
Sbjct: 308 ECEINNGGCSVAPPVECVNTPGSSHCQACPPG--YQGDGRVCTLTDICSVSNGGCHPDAS 365
Query: 297 YER--GDIP--PTFPTRTE---------------LASPCDNGRCINTHGGFECECELGYV 337
G +P P T L+ PC NG+CI+T G+ C+C+ G+
Sbjct: 366 CSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWT 425
Query: 338 -LDAT--AQRCLDN---RRGSCWRRVVDGQCE 363
++ T CL N G+C V CE
Sbjct: 426 GVNCTENINECLSNPCLNGGTCVDGVDSFSCE 457
Score = 76.6 bits (180), Expect = 2e-13
Identities = 63/185 (34%), Positives = 78/185 (42%), Gaps = 23/185 (12%)
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLP---GFTLSNDGRTCLGLKLGWGVSCQ---A 172
VD C G C N SF C C P G S D C + G +SCQ
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNEC-EIYSGTPLSCQNGGT 189
Query: 173 C-PAQGSELYAVLCPEGPSKDNGGADINECTAVPGA-CPHGSCENL------EPGYRCIC 224
C GS Y+ CP + ++C A C HG CE+L EP Y C+C
Sbjct: 190 CVNTMGS--YSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVC 247
Query: 225 DPG--YHPDADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTC-VCPEGTRHEPELQLCRD 280
D G + P++ D DEC C+ QC NT GSF C CP G + +C D
Sbjct: 248 DAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNG--YICED 305
Query: 281 IDECE 285
I+ECE
Sbjct: 306 INECE 310
Score = 64.1 bits (149), Expect = 1e-09
Identities = 47/157 (29%), Positives = 66/157 (42%), Gaps = 13/157 (8%)
Query: 5 GMCTNGI-CKNIDGGFEC-ICKPGYESGSEGALCRDVDECRDNPRVCRRG---RCRNTAG 59
G C+ + C N G F C C G++ G +C D++EC N C C NT G
Sbjct: 272 GPCSTLVQCFNTQGSFYCGACPTGWQGN--GYICEDINECEINNGGCSVAPPVECVNTPG 329
Query: 60 SYTC-LCEPGFAPTAAGYCADVDECA-ADSMCK-GGRCVNSEGSFQ-CVCEAGYRPTATR 115
S C C PG+ C D C+ ++ C C ++ GS C C GY
Sbjct: 330 SSHCQACPPGYQGDGR-VCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYG 388
Query: 116 -GACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT 151
CV + C NG+C +T + C+C G+T
Sbjct: 389 PNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWT 425
Score = 61.3 bits (142), Expect = 7e-09
Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 7/108 (6%)
Query: 1 MTNGGMCTNGICKNIDGGFE-CICKPGYESGSEGAL-CRDVDE-CRDNPRVCRRGRCRNT 57
++NGG + C + G C C PGY G C + C +P C G+C +T
Sbjct: 355 VSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHP--CLNGQCIDT 412
Query: 58 AGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVC 105
Y C C+ G+ T +++EC ++ GG CV+ SF C C
Sbjct: 413 VSGYFCKCDSGW--TGVNCTENINECLSNPCLNGGTCVDGVDSFSCEC 458
Score = 41.1 bits (92), Expect = 0.008
Identities = 59/228 (25%), Positives = 87/228 (38%), Gaps = 34/228 (14%)
Query: 234 GLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCR-DIDECEGETETH 291
GL + +D+ + C GG C N SF C+CP + LC D++ECE + T
Sbjct: 126 GLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGP----LCSADVNECEIYSGTP 181
Query: 292 YIESDYERGDIPPTFPTRTELASPCDNG-RCINTHGGFECECELGYVLDATAQRCLDNRR 350
S G T + + P G +C + + +CE G V C D R
Sbjct: 182 L--SCQNGGTCVNTMGSYSCHCPPETYGPQCASKYD----DCEGGSVARCVHGICEDLMR 235
Query: 351 GSCWRRVVDGQCEAA------APELLL-RQEC------CCSVGLAWGSXXXXXXXXXXXX 397
C+A +P L R EC C ++ + +
Sbjct: 236 EQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTG 295
Query: 398 XKGFAKLDGATCRDVDECALSAELCAGG---TCVNTDGSYRCD-CPPG 441
+G +G C D++EC ++ C+ CVNT GS C CPPG
Sbjct: 296 WQG----NGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPG 339
>AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein
protein.
Length = 3574
Score = 101 bits (241), Expect = 7e-21
Identities = 63/227 (27%), Positives = 99/227 (43%), Gaps = 20/227 (8%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N G C+ + G+ C+C GY G C D+DEC P G C++ G + C
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGY----TGLKCETDIDECSPLP-CLNNGVCKDLVGEFICE 1256
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ T +++EC++ G CV+ ++C C G+ +V+EC
Sbjct: 1257 CPSGY--TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCE---TEVNEC 1311
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT---CLGLKLGWGVSCQACPAQGSELY 181
+ N C + G F C+C PGF + G+ CL G +C+ G+ +
Sbjct: 1312 QSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK----DGANSF 1367
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
LC G + + +INEC + P +C + Y C C PG+
Sbjct: 1368 RCLCAAGFTGSHCELNINECQSNP-CRNQATCVDELNSYSCKCQPGF 1413
Score = 88.2 bits (209), Expect = 5e-17
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 16/149 (10%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N GIC + G+ C C G+ G C +V+EC+ NP + C + G + C
Sbjct: 1278 CLNKGICVDGVAGYRCTCVKGFV----GLHCETEVNECQSNPCL-NNAVCEDQVGGFLCK 1332
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDVDE 123
C PGF T G +VDEC + G C + SF+C+C AG+ T C ++++E
Sbjct: 1333 CPPGFLGTRCG--KNVDECLSQPCKNGATCKDGANSFRCLCAAGF----TGSHCELNINE 1386
Query: 124 CEEQRVCRN-GRCHNTPGSFRCECLPGFT 151
C + CRN C + S+ C+C PGF+
Sbjct: 1387 C-QSNPCRNQATCVDELNSYSCKCQPGFS 1414
Score = 80.2 bits (189), Expect = 1e-14
Identities = 62/237 (26%), Positives = 96/237 (40%), Gaps = 29/237 (12%)
Query: 41 ECRDNPRVCRR-GRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEG 99
EC NP C G C+ Y CLC G+ T D+DEC+ G C + G
Sbjct: 1196 ECFFNP--CHNSGTCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCLNNGVCKDLVG 1251
Query: 100 SFQCVCEAGYRPTATRGACVD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
F C C +GY T C + ++EC G C + +RC C+ GF +
Sbjct: 1252 EFICECPSGY----TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1307
Query: 159 CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLE 217
+ ++ C Q + CP G G +++EC + P C +G +C++
Sbjct: 1308 VNECQSNPCLNNAVCEDQVGG-FLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGA 1364
Query: 218 PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTA------GSFTCVCPEG 268
+RC+C G+ C+++ + C CRN A S++C C G
Sbjct: 1365 NSFRCLCAAGFTG---------SHCELNINECQSNPCRNQATCVDELNSYSCKCQPG 1412
Score = 76.6 bits (180), Expect = 2e-13
Identities = 57/205 (27%), Positives = 84/205 (40%), Gaps = 13/205 (6%)
Query: 82 ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
EC + G C + C+C GY D+DEC NG C + G
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCE---TDIDECSPLPCLNNGVCKDLVGE 1252
Query: 142 FRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINEC 201
F CEC G+T ++ C G Y C +G + ++NEC
Sbjct: 1253 FICECPSGYTGQRCEENINECSSSPCLNKGIC-VDGVAGYRCTCVKGFVGLHCETEVNEC 1311
Query: 202 TAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSF 261
+ P + CE+ G+ C C PG+ G +++DEC + Q G C++ A SF
Sbjct: 1312 QSNP-CLNNAVCEDQVGGFLCKCPPGFLGTRCG--KNVDEC-LSQPCKNGATCKDGANSF 1367
Query: 262 TCVCPEG-TRHEPELQLCRDIDECE 285
C+C G T EL +I+EC+
Sbjct: 1368 RCLCAAGFTGSHCEL----NINECQ 1388
Score = 49.6 bits (113), Expect = 2e-05
Identities = 60/242 (24%), Positives = 89/242 (36%), Gaps = 24/242 (9%)
Query: 49 CRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG 108
C R + AG CL P + T + EC++ S +E S G
Sbjct: 1126 CPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSA----AEESVVPPASLG 1181
Query: 109 YRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLK-L 164
+ + EC +G C + C C G+T D C L L
Sbjct: 1182 HIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCL 1241
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
GV C+ + + CP G + +INEC++ P G C + GYRC C
Sbjct: 1242 NNGV-CKDLVGE----FICECPSGYTGQRCEENINECSSSP-CLNKGICVDGVAGYRCTC 1295
Query: 225 DPGYHPDADGL-CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDID 282
G+ GL C +++EC + C + G F C CP G + +++D
Sbjct: 1296 VKGF----VGLHCETEVNECQSNPC-LNNAVCEDQVGGFLCKCPPGFL---GTRCGKNVD 1347
Query: 283 EC 284
EC
Sbjct: 1348 EC 1349
Score = 48.0 bits (109), Expect = 7e-05
Identities = 19/43 (44%), Positives = 25/43 (58%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
+C DVDECA+ ++ +C+N DGSY C C P T D A
Sbjct: 1745 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPSYTGDGKNCA 1787
Score = 42.3 bits (95), Expect = 0.003
Identities = 46/190 (24%), Positives = 65/190 (34%), Gaps = 28/190 (14%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C NG D C + S C DVDEC C N GSY C C
Sbjct: 1719 CNNGYYLLGDSRMFCTDNGSWNGVSPS--CLDVDECAVGSDCSEHASCLNVDGSYICSCV 1776
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGR------CVNSEGSFQCVCEAGYR-PTATRGACV 119
P + CA+ +C A + G V +E +F C+ GY+ T+ C+
Sbjct: 1777 PSYTGDGKN-CAEPIKCKAPGNPENGHSSGEIYTVGAEVTFS--CQEGYQLMGVTKITCL 1833
Query: 120 DVDE------------CEEQRVCRNGRCHNTPGSFRCE----CLPGFTLSNDGRTCLGLK 163
+ E C + + NG +F + C G+TL+ D +
Sbjct: 1834 ESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLAN 1893
Query: 164 LGWGVSCQAC 173
W S C
Sbjct: 1894 SSWSHSPPVC 1903
Score = 38.7 bits (86), Expect = 0.042
Identities = 41/142 (28%), Positives = 53/142 (37%), Gaps = 19/142 (13%)
Query: 314 SPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGSCWRRVVDGQCEA 364
+PC N G C G+ C C LGY + + + CL+N G C V + CE
Sbjct: 1200 NPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNN--GVCKDLVGEFICEC 1257
Query: 365 AAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSA 419
+ R EC S L G KGF L T +V+EC S
Sbjct: 1258 PSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET--EVNECQ-SN 1314
Query: 420 ELCAGGTCVNTDGSYRCDCPPG 441
C + G + C CPPG
Sbjct: 1315 PCLNNAVCEDQVGGFLCKCPPG 1336
Score = 37.9 bits (84), Expect = 0.073
Identities = 93/384 (24%), Positives = 129/384 (33%), Gaps = 54/384 (14%)
Query: 89 CKGGRCVNSEGSFQC-VCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECL 147
C+ G + EG +C +C +G ++ +C+ Q C+ G ++ G CE
Sbjct: 1018 CRIGSYQDEEGQLECKLCPSGMYTEYIHSR--NISDCKAQ--CKQGT-YSCSGLETCESC 1072
Query: 148 PGFTLSND--GRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVP 205
P T R+CL S A V CPEG +G + C
Sbjct: 1073 PLGTYQPKFGSRSCLSCPEN--TSTVKRGAVNISACGVPCPEGKFSRSG---LMPCHP-- 1125
Query: 206 GACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQS-YCAGGQCRNTAGSFTCV 264
CP + C+ P Y R I EC S + A + S +
Sbjct: 1126 --CPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHI 1183
Query: 265 CPEGTRHEPELQLCRD--IDECEGETETHYIESDY----ERGDIPPTFPTRTELASP--C 316
RHE Q+ + + C + Y G T + SP C
Sbjct: 1184 ---KKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPC 1240
Query: 317 -DNGRCINTHGGFECECELGYVLDATAQRCLDN----------RRGSCWRRVVDGQCEAA 365
+NG C + G F CEC GY T QRC +N +G C V +C
Sbjct: 1241 LNNGVCKDLVGEFICECPSGY----TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCV 1296
Query: 366 APELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALSA 419
+ L EC + L GF G C ++VDEC LS
Sbjct: 1297 KGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFL---GTRCGKNVDEC-LSQ 1352
Query: 420 ELCAGGTCVNTDGSYRCDCPPGLT 443
G TC + S+RC C G T
Sbjct: 1353 PCKNGATCKDGANSFRCLCAAGFT 1376
Score = 36.3 bits (80), Expect = 0.22
Identities = 20/75 (26%), Positives = 30/75 (40%), Gaps = 4/75 (5%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDM---HQSYCAGGQ 253
D++EC H SC N++ Y C C P Y D C + +C ++ + G+
Sbjct: 1748 DVDECAVGSDCSEHASCLNVDGSYICSCVPSYTGDGKN-CAEPIKCKAPGNPENGHSSGE 1806
Query: 254 CRNTAGSFTCVCPEG 268
T C EG
Sbjct: 1807 IYTVGAEVTFSCQEG 1821
Score = 31.9 bits (69), Expect = 4.8
Identities = 38/133 (28%), Positives = 47/133 (35%), Gaps = 16/133 (12%)
Query: 139 PGS-FRCECLPGFTL-SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA 196
PGS C PGF L N + CL G Q P + C P +NG
Sbjct: 1653 PGSKVNLFCDPGFQLVGNPVQYCLNQ----GQWTQPLP----HCERISCGVPPPLENGFH 1704
Query: 197 DINECTAVPGACPHGSCEN---LEPGYRCIC-DPGYHPDADGLCRDIDECDMHQSYCAGG 252
++ A G+ C N L R C D G C D+DEC +
Sbjct: 1705 SADDFYA--GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHA 1762
Query: 253 QCRNTAGSFTCVC 265
C N GS+ C C
Sbjct: 1763 SCLNVDGSYICSC 1775
>AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 101 bits (241), Expect = 7e-21
Identities = 63/227 (27%), Positives = 99/227 (43%), Gaps = 20/227 (8%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N G C+ + G+ C+C GY G C D+DEC P G C++ G + C
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPLGY----TGLKCETDIDECSPLP-CLNNGVCKDLVGEFICE 1233
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ T +++EC++ G CV+ ++C C G+ +V+EC
Sbjct: 1234 CPSGY--TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCE---TEVNEC 1288
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT---CLGLKLGWGVSCQACPAQGSELY 181
+ N C + G F C+C PGF + G+ CL G +C+ G+ +
Sbjct: 1289 QSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK----DGANSF 1344
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
LC G + + +INEC + P +C + Y C C PG+
Sbjct: 1345 RCLCAAGFTGSHCELNINECQSNP-CRNQATCVDELNSYSCKCQPGF 1390
Score = 88.2 bits (209), Expect = 5e-17
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 16/149 (10%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N GIC + G+ C C G+ G C +V+EC+ NP + C + G + C
Sbjct: 1255 CLNKGICVDGVAGYRCTCVKGFV----GLHCETEVNECQSNPCL-NNAVCEDQVGGFLCK 1309
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDVDE 123
C PGF T G +VDEC + G C + SF+C+C AG+ T C ++++E
Sbjct: 1310 CPPGFLGTRCG--KNVDECLSQPCKNGATCKDGANSFRCLCAAGF----TGSHCELNINE 1363
Query: 124 CEEQRVCRN-GRCHNTPGSFRCECLPGFT 151
C + CRN C + S+ C+C PGF+
Sbjct: 1364 C-QSNPCRNQATCVDELNSYSCKCQPGFS 1391
Score = 80.2 bits (189), Expect = 1e-14
Identities = 62/237 (26%), Positives = 96/237 (40%), Gaps = 29/237 (12%)
Query: 41 ECRDNPRVCRR-GRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEG 99
EC NP C G C+ Y CLC G+ T D+DEC+ G C + G
Sbjct: 1173 ECFFNP--CHNSGTCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCLNNGVCKDLVG 1228
Query: 100 SFQCVCEAGYRPTATRGACVD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
F C C +GY T C + ++EC G C + +RC C+ GF +
Sbjct: 1229 EFICECPSGY----TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1284
Query: 159 CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLE 217
+ ++ C Q + CP G G +++EC + P C +G +C++
Sbjct: 1285 VNECQSNPCLNNAVCEDQVGG-FLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGA 1341
Query: 218 PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTA------GSFTCVCPEG 268
+RC+C G+ C+++ + C CRN A S++C C G
Sbjct: 1342 NSFRCLCAAGFTG---------SHCELNINECQSNPCRNQATCVDELNSYSCKCQPG 1389
Score = 76.6 bits (180), Expect = 2e-13
Identities = 57/205 (27%), Positives = 84/205 (40%), Gaps = 13/205 (6%)
Query: 82 ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
EC + G C + C+C GY D+DEC NG C + G
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCE---TDIDECSPLPCLNNGVCKDLVGE 1229
Query: 142 FRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINEC 201
F CEC G+T ++ C G Y C +G + ++NEC
Sbjct: 1230 FICECPSGYTGQRCEENINECSSSPCLNKGIC-VDGVAGYRCTCVKGFVGLHCETEVNEC 1288
Query: 202 TAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSF 261
+ P + CE+ G+ C C PG+ G +++DEC + Q G C++ A SF
Sbjct: 1289 QSNP-CLNNAVCEDQVGGFLCKCPPGFLGTRCG--KNVDEC-LSQPCKNGATCKDGANSF 1344
Query: 262 TCVCPEG-TRHEPELQLCRDIDECE 285
C+C G T EL +I+EC+
Sbjct: 1345 RCLCAAGFTGSHCEL----NINECQ 1365
Score = 49.6 bits (113), Expect = 2e-05
Identities = 60/242 (24%), Positives = 89/242 (36%), Gaps = 24/242 (9%)
Query: 49 CRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG 108
C R + AG CL P + T + EC++ S +E S G
Sbjct: 1103 CPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSA----AEESVVPPASLG 1158
Query: 109 YRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLK-L 164
+ + EC +G C + C C G+T D C L L
Sbjct: 1159 HIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCL 1218
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
GV C+ + + CP G + +INEC++ P G C + GYRC C
Sbjct: 1219 NNGV-CKDLVGE----FICECPSGYTGQRCEENINECSSSP-CLNKGICVDGVAGYRCTC 1272
Query: 225 DPGYHPDADGL-CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDID 282
G+ GL C +++EC + C + G F C CP G + +++D
Sbjct: 1273 VKGF----VGLHCETEVNECQSNPC-LNNAVCEDQVGGFLCKCPPGFL---GTRCGKNVD 1324
Query: 283 EC 284
EC
Sbjct: 1325 EC 1326
Score = 47.2 bits (107), Expect = 1e-04
Identities = 19/43 (44%), Positives = 25/43 (58%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
+C DVDECA+ ++ +C+N DGSY C C P T D A
Sbjct: 1719 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCA 1761
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/190 (24%), Positives = 65/190 (34%), Gaps = 28/190 (14%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C NG D C + S C DVDEC C N GSY C C
Sbjct: 1693 CNNGYYLLGDSRMFCTDNGSWNGVSPS--CLDVDECAVGSDCSEHASCLNVDGSYICSCV 1750
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGR------CVNSEGSFQCVCEAGYR-PTATRGACV 119
P + CA+ +C A + G V +E +F C+ GY+ T+ C+
Sbjct: 1751 PPYTGDGKN-CAEPIKCKAPGNPENGHSSGEIYTVGAEVTFS--CQEGYQLMGVTKITCL 1807
Query: 120 DVDE------------CEEQRVCRNGRCHNTPGSFRCE----CLPGFTLSNDGRTCLGLK 163
+ E C + + NG +F + C G+TL+ D +
Sbjct: 1808 ESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLAN 1867
Query: 164 LGWGVSCQAC 173
W S C
Sbjct: 1868 SSWSHSPPVC 1877
Score = 38.7 bits (86), Expect = 0.042
Identities = 41/142 (28%), Positives = 53/142 (37%), Gaps = 19/142 (13%)
Query: 314 SPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGSCWRRVVDGQCEA 364
+PC N G C G+ C C LGY + + + CL+N G C V + CE
Sbjct: 1177 NPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNN--GVCKDLVGEFICEC 1234
Query: 365 AAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSA 419
+ R EC S L G KGF L T +V+EC S
Sbjct: 1235 PSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET--EVNECQ-SN 1291
Query: 420 ELCAGGTCVNTDGSYRCDCPPG 441
C + G + C CPPG
Sbjct: 1292 PCLNNAVCEDQVGGFLCKCPPG 1313
Score = 37.5 bits (83), Expect = 0.097
Identities = 44/146 (30%), Positives = 55/146 (37%), Gaps = 25/146 (17%)
Query: 315 PC-DNGRCINTHGGFECECELGYVLDATAQRCLDN----------RRGSCWRRVVDGQCE 363
PC +NG C + G F CEC GY T QRC +N +G C V +C
Sbjct: 1216 PCLNNGVCKDLVGEFICECPSGY----TGQRCEENINECSSSPCLNKGICVDGVAGYRCT 1271
Query: 364 AAAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECAL 417
+ L EC + L GF G C ++VDEC L
Sbjct: 1272 CVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFL---GTRCGKNVDEC-L 1327
Query: 418 SAELCAGGTCVNTDGSYRCDCPPGLT 443
S G TC + S+RC C G T
Sbjct: 1328 SQPCKNGATCKDGANSFRCLCAAGFT 1353
Score = 35.5 bits (78), Expect = 0.39
Identities = 20/75 (26%), Positives = 30/75 (40%), Gaps = 4/75 (5%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDM---HQSYCAGGQ 253
D++EC H SC N++ Y C C P Y D C + +C ++ + G+
Sbjct: 1722 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKN-CAEPIKCKAPGNPENGHSSGE 1780
Query: 254 CRNTAGSFTCVCPEG 268
T C EG
Sbjct: 1781 IYTVGAEVTFSCQEG 1795
Score = 31.9 bits (69), Expect = 4.8
Identities = 38/133 (28%), Positives = 47/133 (35%), Gaps = 16/133 (12%)
Query: 139 PGS-FRCECLPGFTL-SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA 196
PGS C PGF L N + CL G Q P + C P +NG
Sbjct: 1627 PGSKVNLFCDPGFQLVGNPVQYCLNQ----GQWTQPLP----HCERISCGVPPPLENGFH 1678
Query: 197 DINECTAVPGACPHGSCEN---LEPGYRCIC-DPGYHPDADGLCRDIDECDMHQSYCAGG 252
++ A G+ C N L R C D G C D+DEC +
Sbjct: 1679 SADDFYA--GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHA 1736
Query: 253 QCRNTAGSFTCVC 265
C N GS+ C C
Sbjct: 1737 SCLNVDGSYICSC 1749
>AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 101 bits (241), Expect = 7e-21
Identities = 63/227 (27%), Positives = 99/227 (43%), Gaps = 20/227 (8%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N G C+ + G+ C+C GY G C D+DEC P G C++ G + C
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPLGY----TGLKCETDIDECSPLP-CLNNGVCKDLVGEFICE 1233
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ T +++EC++ G CV+ ++C C G+ +V+EC
Sbjct: 1234 CPSGY--TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCE---TEVNEC 1288
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT---CLGLKLGWGVSCQACPAQGSELY 181
+ N C + G F C+C PGF + G+ CL G +C+ G+ +
Sbjct: 1289 QSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK----DGANSF 1344
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
LC G + + +INEC + P +C + Y C C PG+
Sbjct: 1345 RCLCAAGFTGSHCELNINECQSNP-CRNQATCVDELNSYSCKCQPGF 1390
Score = 88.2 bits (209), Expect = 5e-17
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 16/149 (10%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N GIC + G+ C C G+ G C +V+EC+ NP + C + G + C
Sbjct: 1255 CLNKGICVDGVAGYRCTCVKGFV----GLHCETEVNECQSNPCL-NNAVCEDQVGGFLCK 1309
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDVDE 123
C PGF T G +VDEC + G C + SF+C+C AG+ T C ++++E
Sbjct: 1310 CPPGFLGTRCG--KNVDECLSQPCKNGATCKDGANSFRCLCAAGF----TGSHCELNINE 1363
Query: 124 CEEQRVCRN-GRCHNTPGSFRCECLPGFT 151
C + CRN C + S+ C+C PGF+
Sbjct: 1364 C-QSNPCRNQATCVDELNSYSCKCQPGFS 1391
Score = 80.2 bits (189), Expect = 1e-14
Identities = 62/237 (26%), Positives = 96/237 (40%), Gaps = 29/237 (12%)
Query: 41 ECRDNPRVCRR-GRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEG 99
EC NP C G C+ Y CLC G+ T D+DEC+ G C + G
Sbjct: 1173 ECFFNP--CHNSGTCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCLNNGVCKDLVG 1228
Query: 100 SFQCVCEAGYRPTATRGACVD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
F C C +GY T C + ++EC G C + +RC C+ GF +
Sbjct: 1229 EFICECPSGY----TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1284
Query: 159 CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLE 217
+ ++ C Q + CP G G +++EC + P C +G +C++
Sbjct: 1285 VNECQSNPCLNNAVCEDQVGG-FLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGA 1341
Query: 218 PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTA------GSFTCVCPEG 268
+RC+C G+ C+++ + C CRN A S++C C G
Sbjct: 1342 NSFRCLCAAGFTG---------SHCELNINECQSNPCRNQATCVDELNSYSCKCQPG 1389
Score = 76.6 bits (180), Expect = 2e-13
Identities = 57/205 (27%), Positives = 84/205 (40%), Gaps = 13/205 (6%)
Query: 82 ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
EC + G C + C+C GY D+DEC NG C + G
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCE---TDIDECSPLPCLNNGVCKDLVGE 1229
Query: 142 FRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINEC 201
F CEC G+T ++ C G Y C +G + ++NEC
Sbjct: 1230 FICECPSGYTGQRCEENINECSSSPCLNKGIC-VDGVAGYRCTCVKGFVGLHCETEVNEC 1288
Query: 202 TAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSF 261
+ P + CE+ G+ C C PG+ G +++DEC + Q G C++ A SF
Sbjct: 1289 QSNP-CLNNAVCEDQVGGFLCKCPPGFLGTRCG--KNVDEC-LSQPCKNGATCKDGANSF 1344
Query: 262 TCVCPEG-TRHEPELQLCRDIDECE 285
C+C G T EL +I+EC+
Sbjct: 1345 RCLCAAGFTGSHCEL----NINECQ 1365
Score = 49.6 bits (113), Expect = 2e-05
Identities = 60/242 (24%), Positives = 89/242 (36%), Gaps = 24/242 (9%)
Query: 49 CRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG 108
C R + AG CL P + T + EC++ S +E S G
Sbjct: 1103 CPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSA----AEESVVPPASLG 1158
Query: 109 YRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLK-L 164
+ + EC +G C + C C G+T D C L L
Sbjct: 1159 HIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCL 1218
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
GV C+ + + CP G + +INEC++ P G C + GYRC C
Sbjct: 1219 NNGV-CKDLVGE----FICECPSGYTGQRCEENINECSSSP-CLNKGICVDGVAGYRCTC 1272
Query: 225 DPGYHPDADGL-CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDID 282
G+ GL C +++EC + C + G F C CP G + +++D
Sbjct: 1273 VKGF----VGLHCETEVNECQSNPC-LNNAVCEDQVGGFLCKCPPGFL---GTRCGKNVD 1324
Query: 283 EC 284
EC
Sbjct: 1325 EC 1326
Score = 47.2 bits (107), Expect = 1e-04
Identities = 19/43 (44%), Positives = 25/43 (58%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
+C DVDECA+ ++ +C+N DGSY C C P T D A
Sbjct: 1719 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCA 1761
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/190 (24%), Positives = 65/190 (34%), Gaps = 28/190 (14%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C NG D C + S C DVDEC C N GSY C C
Sbjct: 1693 CNNGYYLLGDSRMFCTDNGSWNGVSPS--CLDVDECAVGSDCSEHASCLNVDGSYICSCV 1750
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGR------CVNSEGSFQCVCEAGYR-PTATRGACV 119
P + CA+ +C A + G V +E +F C+ GY+ T+ C+
Sbjct: 1751 PPYTGDGKN-CAEPIKCKAPGNPENGHSSGEIYTVGAEVTFS--CQEGYQLMGVTKITCL 1807
Query: 120 DVDE------------CEEQRVCRNGRCHNTPGSFRCE----CLPGFTLSNDGRTCLGLK 163
+ E C + + NG +F + C G+TL+ D +
Sbjct: 1808 ESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLAN 1867
Query: 164 LGWGVSCQAC 173
W S C
Sbjct: 1868 SSWSHSPPVC 1877
Score = 38.7 bits (86), Expect = 0.042
Identities = 41/142 (28%), Positives = 53/142 (37%), Gaps = 19/142 (13%)
Query: 314 SPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGSCWRRVVDGQCEA 364
+PC N G C G+ C C LGY + + + CL+N G C V + CE
Sbjct: 1177 NPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNN--GVCKDLVGEFICEC 1234
Query: 365 AAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSA 419
+ R EC S L G KGF L T +V+EC S
Sbjct: 1235 PSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET--EVNECQ-SN 1291
Query: 420 ELCAGGTCVNTDGSYRCDCPPG 441
C + G + C CPPG
Sbjct: 1292 PCLNNAVCEDQVGGFLCKCPPG 1313
Score = 37.5 bits (83), Expect = 0.097
Identities = 44/146 (30%), Positives = 55/146 (37%), Gaps = 25/146 (17%)
Query: 315 PC-DNGRCINTHGGFECECELGYVLDATAQRCLDN----------RRGSCWRRVVDGQCE 363
PC +NG C + G F CEC GY T QRC +N +G C V +C
Sbjct: 1216 PCLNNGVCKDLVGEFICECPSGY----TGQRCEENINECSSSPCLNKGICVDGVAGYRCT 1271
Query: 364 AAAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECAL 417
+ L EC + L GF G C ++VDEC L
Sbjct: 1272 CVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFL---GTRCGKNVDEC-L 1327
Query: 418 SAELCAGGTCVNTDGSYRCDCPPGLT 443
S G TC + S+RC C G T
Sbjct: 1328 SQPCKNGATCKDGANSFRCLCAAGFT 1353
Score = 35.5 bits (78), Expect = 0.39
Identities = 20/75 (26%), Positives = 30/75 (40%), Gaps = 4/75 (5%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDM---HQSYCAGGQ 253
D++EC H SC N++ Y C C P Y D C + +C ++ + G+
Sbjct: 1722 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKN-CAEPIKCKAPGNPENGHSSGE 1780
Query: 254 CRNTAGSFTCVCPEG 268
T C EG
Sbjct: 1781 IYTVGAEVTFSCQEG 1795
Score = 31.9 bits (69), Expect = 4.8
Identities = 38/133 (28%), Positives = 47/133 (35%), Gaps = 16/133 (12%)
Query: 139 PGS-FRCECLPGFTL-SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA 196
PGS C PGF L N + CL G Q P + C P +NG
Sbjct: 1627 PGSKVNLFCDPGFQLVGNPVQYCLNQ----GQWTQPLP----HCERISCGVPPPLENGFH 1678
Query: 197 DINECTAVPGACPHGSCEN---LEPGYRCIC-DPGYHPDADGLCRDIDECDMHQSYCAGG 252
++ A G+ C N L R C D G C D+DEC +
Sbjct: 1679 SADDFYA--GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHA 1736
Query: 253 QCRNTAGSFTCVC 265
C N GS+ C C
Sbjct: 1737 SCLNVDGSYICSC 1749
>AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 101 bits (241), Expect = 7e-21
Identities = 63/227 (27%), Positives = 99/227 (43%), Gaps = 20/227 (8%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N G C+ + G+ C+C GY G C D+DEC P G C++ G + C
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPLGY----TGLKCETDIDECSPLP-CLNNGVCKDLVGEFICE 1233
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ T +++EC++ G CV+ ++C C G+ +V+EC
Sbjct: 1234 CPSGY--TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCE---TEVNEC 1288
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT---CLGLKLGWGVSCQACPAQGSELY 181
+ N C + G F C+C PGF + G+ CL G +C+ G+ +
Sbjct: 1289 QSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK----DGANSF 1344
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
LC G + + +INEC + P +C + Y C C PG+
Sbjct: 1345 RCLCAAGFTGSHCELNINECQSNP-CRNQATCVDELNSYSCKCQPGF 1390
Score = 88.2 bits (209), Expect = 5e-17
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 16/149 (10%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N GIC + G+ C C G+ G C +V+EC+ NP + C + G + C
Sbjct: 1255 CLNKGICVDGVAGYRCTCVKGFV----GLHCETEVNECQSNPCL-NNAVCEDQVGGFLCK 1309
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDVDE 123
C PGF T G +VDEC + G C + SF+C+C AG+ T C ++++E
Sbjct: 1310 CPPGFLGTRCG--KNVDECLSQPCKNGATCKDGANSFRCLCAAGF----TGSHCELNINE 1363
Query: 124 CEEQRVCRN-GRCHNTPGSFRCECLPGFT 151
C + CRN C + S+ C+C PGF+
Sbjct: 1364 C-QSNPCRNQATCVDELNSYSCKCQPGFS 1391
Score = 80.2 bits (189), Expect = 1e-14
Identities = 62/237 (26%), Positives = 96/237 (40%), Gaps = 29/237 (12%)
Query: 41 ECRDNPRVCRR-GRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEG 99
EC NP C G C+ Y CLC G+ T D+DEC+ G C + G
Sbjct: 1173 ECFFNP--CHNSGTCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCLNNGVCKDLVG 1228
Query: 100 SFQCVCEAGYRPTATRGACVD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
F C C +GY T C + ++EC G C + +RC C+ GF +
Sbjct: 1229 EFICECPSGY----TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1284
Query: 159 CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLE 217
+ ++ C Q + CP G G +++EC + P C +G +C++
Sbjct: 1285 VNECQSNPCLNNAVCEDQVGG-FLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGA 1341
Query: 218 PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTA------GSFTCVCPEG 268
+RC+C G+ C+++ + C CRN A S++C C G
Sbjct: 1342 NSFRCLCAAGFTG---------SHCELNINECQSNPCRNQATCVDELNSYSCKCQPG 1389
Score = 76.6 bits (180), Expect = 2e-13
Identities = 57/205 (27%), Positives = 84/205 (40%), Gaps = 13/205 (6%)
Query: 82 ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
EC + G C + C+C GY D+DEC NG C + G
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCE---TDIDECSPLPCLNNGVCKDLVGE 1229
Query: 142 FRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINEC 201
F CEC G+T ++ C G Y C +G + ++NEC
Sbjct: 1230 FICECPSGYTGQRCEENINECSSSPCLNKGIC-VDGVAGYRCTCVKGFVGLHCETEVNEC 1288
Query: 202 TAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSF 261
+ P + CE+ G+ C C PG+ G +++DEC + Q G C++ A SF
Sbjct: 1289 QSNP-CLNNAVCEDQVGGFLCKCPPGFLGTRCG--KNVDEC-LSQPCKNGATCKDGANSF 1344
Query: 262 TCVCPEG-TRHEPELQLCRDIDECE 285
C+C G T EL +I+EC+
Sbjct: 1345 RCLCAAGFTGSHCEL----NINECQ 1365
Score = 49.6 bits (113), Expect = 2e-05
Identities = 60/242 (24%), Positives = 89/242 (36%), Gaps = 24/242 (9%)
Query: 49 CRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG 108
C R + AG CL P + T + EC++ S +E S G
Sbjct: 1103 CPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSA----AEESVVPPASLG 1158
Query: 109 YRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLK-L 164
+ + EC +G C + C C G+T D C L L
Sbjct: 1159 HIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCL 1218
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
GV C+ + + CP G + +INEC++ P G C + GYRC C
Sbjct: 1219 NNGV-CKDLVGE----FICECPSGYTGQRCEENINECSSSP-CLNKGICVDGVAGYRCTC 1272
Query: 225 DPGYHPDADGL-CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDID 282
G+ GL C +++EC + C + G F C CP G + +++D
Sbjct: 1273 VKGF----VGLHCETEVNECQSNPC-LNNAVCEDQVGGFLCKCPPGFL---GTRCGKNVD 1324
Query: 283 EC 284
EC
Sbjct: 1325 EC 1326
Score = 47.2 bits (107), Expect = 1e-04
Identities = 19/43 (44%), Positives = 25/43 (58%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
+C DVDECA+ ++ +C+N DGSY C C P T D A
Sbjct: 1719 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCA 1761
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/190 (24%), Positives = 65/190 (34%), Gaps = 28/190 (14%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C NG D C + S C DVDEC C N GSY C C
Sbjct: 1693 CNNGYYLLGDSRMFCTDNGSWNGVSPS--CLDVDECAVGSDCSEHASCLNVDGSYICSCV 1750
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGR------CVNSEGSFQCVCEAGYR-PTATRGACV 119
P + CA+ +C A + G V +E +F C+ GY+ T+ C+
Sbjct: 1751 PPYTGDGKN-CAEPIKCKAPGNPENGHSSGEIYTVGAEVTFS--CQEGYQLMGVTKITCL 1807
Query: 120 DVDE------------CEEQRVCRNGRCHNTPGSFRCE----CLPGFTLSNDGRTCLGLK 163
+ E C + + NG +F + C G+TL+ D +
Sbjct: 1808 ESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLAN 1867
Query: 164 LGWGVSCQAC 173
W S C
Sbjct: 1868 SSWSHSPPVC 1877
Score = 38.7 bits (86), Expect = 0.042
Identities = 41/142 (28%), Positives = 53/142 (37%), Gaps = 19/142 (13%)
Query: 314 SPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGSCWRRVVDGQCEA 364
+PC N G C G+ C C LGY + + + CL+N G C V + CE
Sbjct: 1177 NPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNN--GVCKDLVGEFICEC 1234
Query: 365 AAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSA 419
+ R EC S L G KGF L T +V+EC S
Sbjct: 1235 PSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET--EVNECQ-SN 1291
Query: 420 ELCAGGTCVNTDGSYRCDCPPG 441
C + G + C CPPG
Sbjct: 1292 PCLNNAVCEDQVGGFLCKCPPG 1313
Score = 37.5 bits (83), Expect = 0.097
Identities = 44/146 (30%), Positives = 55/146 (37%), Gaps = 25/146 (17%)
Query: 315 PC-DNGRCINTHGGFECECELGYVLDATAQRCLDN----------RRGSCWRRVVDGQCE 363
PC +NG C + G F CEC GY T QRC +N +G C V +C
Sbjct: 1216 PCLNNGVCKDLVGEFICECPSGY----TGQRCEENINECSSSPCLNKGICVDGVAGYRCT 1271
Query: 364 AAAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECAL 417
+ L EC + L GF G C ++VDEC L
Sbjct: 1272 CVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFL---GTRCGKNVDEC-L 1327
Query: 418 SAELCAGGTCVNTDGSYRCDCPPGLT 443
S G TC + S+RC C G T
Sbjct: 1328 SQPCKNGATCKDGANSFRCLCAAGFT 1353
Score = 35.5 bits (78), Expect = 0.39
Identities = 20/75 (26%), Positives = 30/75 (40%), Gaps = 4/75 (5%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDM---HQSYCAGGQ 253
D++EC H SC N++ Y C C P Y D C + +C ++ + G+
Sbjct: 1722 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKN-CAEPIKCKAPGNPENGHSSGE 1780
Query: 254 CRNTAGSFTCVCPEG 268
T C EG
Sbjct: 1781 IYTVGAEVTFSCQEG 1795
Score = 31.9 bits (69), Expect = 4.8
Identities = 38/133 (28%), Positives = 47/133 (35%), Gaps = 16/133 (12%)
Query: 139 PGS-FRCECLPGFTL-SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA 196
PGS C PGF L N + CL G Q P + C P +NG
Sbjct: 1627 PGSKVNLFCDPGFQLVGNPVQYCLNQ----GQWTQPLP----HCERISCGVPPPLENGFH 1678
Query: 197 DINECTAVPGACPHGSCEN---LEPGYRCIC-DPGYHPDADGLCRDIDECDMHQSYCAGG 252
++ A G+ C N L R C D G C D+DEC +
Sbjct: 1679 SADDFYA--GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHA 1736
Query: 253 QCRNTAGSFTCVC 265
C N GS+ C C
Sbjct: 1737 SCLNVDGSYICSC 1749
>AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens cDNA
FLJ14964 fis, clone PLACE4000581, moderately similar to
FIBROPELLIN I PRECURSOR. ).
Length = 1316
Score = 101 bits (241), Expect = 7e-21
Identities = 63/227 (27%), Positives = 99/227 (43%), Gaps = 20/227 (8%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N G C+ + G+ C+C GY G C D+DEC P G C++ G + C
Sbjct: 969 CHNSGTCQQLGRGYVCLCPLGY----TGLKCETDIDECSPLP-CLNNGVCKDLVGEFICE 1023
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ T +++EC++ G CV+ ++C C G+ +V+EC
Sbjct: 1024 CPSGY--TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCE---TEVNEC 1078
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT---CLGLKLGWGVSCQACPAQGSELY 181
+ N C + G F C+C PGF + G+ CL G +C+ G+ +
Sbjct: 1079 QSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK----DGANSF 1134
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
LC G + + +INEC + P +C + Y C C PG+
Sbjct: 1135 RCLCAAGFTGSHCELNINECQSNP-CRNQATCVDELNSYSCKCQPGF 1180
Score = 88.2 bits (209), Expect = 5e-17
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 16/149 (10%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N GIC + G+ C C G+ G C +V+EC+ NP + C + G + C
Sbjct: 1045 CLNKGICVDGVAGYRCTCVKGFV----GLHCETEVNECQSNPCL-NNAVCEDQVGGFLCK 1099
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDVDE 123
C PGF T G +VDEC + G C + SF+C+C AG+ T C ++++E
Sbjct: 1100 CPPGFLGTRCG--KNVDECLSQPCKNGATCKDGANSFRCLCAAGF----TGSHCELNINE 1153
Query: 124 CEEQRVCRN-GRCHNTPGSFRCECLPGFT 151
C + CRN C + S+ C+C PGF+
Sbjct: 1154 C-QSNPCRNQATCVDELNSYSCKCQPGFS 1181
Score = 80.2 bits (189), Expect = 1e-14
Identities = 62/237 (26%), Positives = 96/237 (40%), Gaps = 29/237 (12%)
Query: 41 ECRDNPRVCRR-GRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEG 99
EC NP C G C+ Y CLC G+ T D+DEC+ G C + G
Sbjct: 963 ECFFNP--CHNSGTCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCLNNGVCKDLVG 1018
Query: 100 SFQCVCEAGYRPTATRGACVD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
F C C +GY T C + ++EC G C + +RC C+ GF +
Sbjct: 1019 EFICECPSGY----TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1074
Query: 159 CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLE 217
+ ++ C Q + CP G G +++EC + P C +G +C++
Sbjct: 1075 VNECQSNPCLNNAVCEDQVGG-FLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGA 1131
Query: 218 PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTA------GSFTCVCPEG 268
+RC+C G+ C+++ + C CRN A S++C C G
Sbjct: 1132 NSFRCLCAAGFTG---------SHCELNINECQSNPCRNQATCVDELNSYSCKCQPG 1179
Score = 76.6 bits (180), Expect = 2e-13
Identities = 57/205 (27%), Positives = 84/205 (40%), Gaps = 13/205 (6%)
Query: 82 ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
EC + G C + C+C GY D+DEC NG C + G
Sbjct: 963 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCE---TDIDECSPLPCLNNGVCKDLVGE 1019
Query: 142 FRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINEC 201
F CEC G+T ++ C G Y C +G + ++NEC
Sbjct: 1020 FICECPSGYTGQRCEENINECSSSPCLNKGIC-VDGVAGYRCTCVKGFVGLHCETEVNEC 1078
Query: 202 TAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSF 261
+ P + CE+ G+ C C PG+ G +++DEC + Q G C++ A SF
Sbjct: 1079 QSNP-CLNNAVCEDQVGGFLCKCPPGFLGTRCG--KNVDEC-LSQPCKNGATCKDGANSF 1134
Query: 262 TCVCPEG-TRHEPELQLCRDIDECE 285
C+C G T EL +I+EC+
Sbjct: 1135 RCLCAAGFTGSHCEL----NINECQ 1155
Score = 49.6 bits (113), Expect = 2e-05
Identities = 60/242 (24%), Positives = 89/242 (36%), Gaps = 24/242 (9%)
Query: 49 CRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG 108
C R + AG CL P + T + EC++ S +E S G
Sbjct: 893 CPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSA----AEESVVPPASLG 948
Query: 109 YRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLK-L 164
+ + EC +G C + C C G+T D C L L
Sbjct: 949 HIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCL 1008
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
GV C+ + + CP G + +INEC++ P G C + GYRC C
Sbjct: 1009 NNGV-CKDLVGE----FICECPSGYTGQRCEENINECSSSP-CLNKGICVDGVAGYRCTC 1062
Query: 225 DPGYHPDADGL-CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDID 282
G+ GL C +++EC + C + G F C CP G + +++D
Sbjct: 1063 VKGF----VGLHCETEVNECQSNPC-LNNAVCEDQVGGFLCKCPPGFL---GTRCGKNVD 1114
Query: 283 EC 284
EC
Sbjct: 1115 EC 1116
Score = 38.7 bits (86), Expect = 0.042
Identities = 41/142 (28%), Positives = 53/142 (37%), Gaps = 19/142 (13%)
Query: 314 SPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGSCWRRVVDGQCEA 364
+PC N G C G+ C C LGY + + + CL+N G C V + CE
Sbjct: 967 NPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNN--GVCKDLVGEFICEC 1024
Query: 365 AAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSA 419
+ R EC S L G KGF L T +V+EC S
Sbjct: 1025 PSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET--EVNECQ-SN 1081
Query: 420 ELCAGGTCVNTDGSYRCDCPPG 441
C + G + C CPPG
Sbjct: 1082 PCLNNAVCEDQVGGFLCKCPPG 1103
Score = 37.9 bits (84), Expect = 0.073
Identities = 93/384 (24%), Positives = 129/384 (33%), Gaps = 54/384 (14%)
Query: 89 CKGGRCVNSEGSFQC-VCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECL 147
C+ G + EG +C +C +G ++ +C+ Q C+ G ++ G CE
Sbjct: 785 CRIGSYQDEEGQLECKLCPSGMYTEYIHSR--NISDCKAQ--CKQGT-YSCSGLETCESC 839
Query: 148 PGFTLSND--GRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVP 205
P T R+CL S A V CPEG +G + C
Sbjct: 840 PLGTYQPKFGSRSCLSCPEN--TSTVKRGAVNISACGVPCPEGKFSRSG---LMPCHP-- 892
Query: 206 GACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQS-YCAGGQCRNTAGSFTCV 264
CP + C+ P Y R I EC S + A + S +
Sbjct: 893 --CPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHI 950
Query: 265 CPEGTRHEPELQLCRD--IDECEGETETHYIESDY----ERGDIPPTFPTRTELASP--C 316
RHE Q+ + + C + Y G T + SP C
Sbjct: 951 ---KKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPC 1007
Query: 317 -DNGRCINTHGGFECECELGYVLDATAQRCLDN----------RRGSCWRRVVDGQCEAA 365
+NG C + G F CEC GY T QRC +N +G C V +C
Sbjct: 1008 LNNGVCKDLVGEFICECPSGY----TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCV 1063
Query: 366 APELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALSA 419
+ L EC + L GF G C ++VDEC LS
Sbjct: 1064 KGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFL---GTRCGKNVDEC-LSQ 1119
Query: 420 ELCAGGTCVNTDGSYRCDCPPGLT 443
G TC + S+RC C G T
Sbjct: 1120 PCKNGATCKDGANSFRCLCAAGFT 1143
>AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.
Length = 3574
Score = 101 bits (241), Expect = 7e-21
Identities = 63/227 (27%), Positives = 99/227 (43%), Gaps = 20/227 (8%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N G C+ + G+ C+C GY G C D+DEC P G C++ G + C
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGY----TGLKCETDIDECSPLP-CLNNGVCKDLVGEFICE 1256
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+ T +++EC++ G CV+ ++C C G+ +V+EC
Sbjct: 1257 CPSGY--TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCE---TEVNEC 1311
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT---CLGLKLGWGVSCQACPAQGSELY 181
+ N C + G F C+C PGF + G+ CL G +C+ G+ +
Sbjct: 1312 QSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK----DGANSF 1367
Query: 182 AVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGY 228
LC G + + +INEC + P +C + Y C C PG+
Sbjct: 1368 RCLCAAGFTGSHCELNINECQSNP-CRNQATCVDELNSYSCKCQPGF 1413
Score = 88.2 bits (209), Expect = 5e-17
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 16/149 (10%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCL 64
C N GIC + G+ C C G+ G C +V+EC+ NP + C + G + C
Sbjct: 1278 CLNKGICVDGVAGYRCTCVKGFV----GLHCETEVNECQSNPCL-NNAVCEDQVGGFLCK 1332
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC-VDVDE 123
C PGF T G +VDEC + G C + SF+C+C AG+ T C ++++E
Sbjct: 1333 CPPGFLGTRCG--KNVDECLSQPCKNGATCKDGANSFRCLCAAGF----TGSHCELNINE 1386
Query: 124 CEEQRVCRN-GRCHNTPGSFRCECLPGFT 151
C + CRN C + S+ C+C PGF+
Sbjct: 1387 C-QSNPCRNQATCVDELNSYSCKCQPGFS 1414
Score = 80.2 bits (189), Expect = 1e-14
Identities = 62/237 (26%), Positives = 96/237 (40%), Gaps = 29/237 (12%)
Query: 41 ECRDNPRVCRR-GRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEG 99
EC NP C G C+ Y CLC G+ T D+DEC+ G C + G
Sbjct: 1196 ECFFNP--CHNSGTCQQLGRGYVCLCPLGY--TGLKCETDIDECSPLPCLNNGVCKDLVG 1251
Query: 100 SFQCVCEAGYRPTATRGACVD-VDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRT 158
F C C +GY T C + ++EC G C + +RC C+ GF +
Sbjct: 1252 EFICECPSGY----TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1307
Query: 159 CLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLE 217
+ ++ C Q + CP G G +++EC + P C +G +C++
Sbjct: 1308 VNECQSNPCLNNAVCEDQVGG-FLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGA 1364
Query: 218 PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTA------GSFTCVCPEG 268
+RC+C G+ C+++ + C CRN A S++C C G
Sbjct: 1365 NSFRCLCAAGFTG---------SHCELNINECQSNPCRNQATCVDELNSYSCKCQPG 1412
Score = 76.6 bits (180), Expect = 2e-13
Identities = 57/205 (27%), Positives = 84/205 (40%), Gaps = 13/205 (6%)
Query: 82 ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGS 141
EC + G C + C+C GY D+DEC NG C + G
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCE---TDIDECSPLPCLNNGVCKDLVGE 1252
Query: 142 FRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINEC 201
F CEC G+T ++ C G Y C +G + ++NEC
Sbjct: 1253 FICECPSGYTGQRCEENINECSSSPCLNKGIC-VDGVAGYRCTCVKGFVGLHCETEVNEC 1311
Query: 202 TAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSF 261
+ P + CE+ G+ C C PG+ G +++DEC + Q G C++ A SF
Sbjct: 1312 QSNP-CLNNAVCEDQVGGFLCKCPPGFLGTRCG--KNVDEC-LSQPCKNGATCKDGANSF 1367
Query: 262 TCVCPEG-TRHEPELQLCRDIDECE 285
C+C G T EL +I+EC+
Sbjct: 1368 RCLCAAGFTGSHCEL----NINECQ 1388
Score = 49.6 bits (113), Expect = 2e-05
Identities = 60/242 (24%), Positives = 89/242 (36%), Gaps = 24/242 (9%)
Query: 49 CRRGRCRNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAG 108
C R + AG CL P + T + EC++ S +E S G
Sbjct: 1126 CPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSA----AEESVVPPASLG 1181
Query: 109 YRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT---LSNDGRTCLGLK-L 164
+ + EC +G C + C C G+T D C L L
Sbjct: 1182 HIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCL 1241
Query: 165 GWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCIC 224
GV C+ + + CP G + +INEC++ P G C + GYRC C
Sbjct: 1242 NNGV-CKDLVGE----FICECPSGYTGQRCEENINECSSSP-CLNKGICVDGVAGYRCTC 1295
Query: 225 DPGYHPDADGL-CR-DIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDID 282
G+ GL C +++EC + C + G F C CP G + +++D
Sbjct: 1296 VKGF----VGLHCETEVNECQSNPC-LNNAVCEDQVGGFLCKCPPGFL---GTRCGKNVD 1347
Query: 283 EC 284
EC
Sbjct: 1348 EC 1349
Score = 48.0 bits (109), Expect = 7e-05
Identities = 19/43 (44%), Positives = 25/43 (58%)
Query: 408 TCRDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGTA 450
+C DVDECA+ ++ +C+N DGSY C C P T D A
Sbjct: 1745 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPSYTGDGKNCA 1787
Score = 42.3 bits (95), Expect = 0.003
Identities = 46/190 (24%), Positives = 65/190 (34%), Gaps = 28/190 (14%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCE 66
C NG D C + S C DVDEC C N GSY C C
Sbjct: 1719 CNNGYYLLGDSRMFCTDNGSWNGVSPS--CLDVDECAVGSDCSEHASCLNVDGSYICSCV 1776
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGR------CVNSEGSFQCVCEAGYR-PTATRGACV 119
P + CA+ +C A + G V +E +F C+ GY+ T+ C+
Sbjct: 1777 PSYTGDGKN-CAEPIKCKAPGNPENGHSSGEIYTVGAEVTFS--CQEGYQLMGVTKITCL 1833
Query: 120 DVDE------------CEEQRVCRNGRCHNTPGSFRCE----CLPGFTLSNDGRTCLGLK 163
+ E C + + NG +F + C G+TL+ D +
Sbjct: 1834 ESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLAN 1893
Query: 164 LGWGVSCQAC 173
W S C
Sbjct: 1894 SSWSHSPPVC 1903
Score = 38.7 bits (86), Expect = 0.042
Identities = 41/142 (28%), Positives = 53/142 (37%), Gaps = 19/142 (13%)
Query: 314 SPCDN-GRCINTHGGFECECELGY--------VLDATAQRCLDNRRGSCWRRVVDGQCEA 364
+PC N G C G+ C C LGY + + + CL+N G C V + CE
Sbjct: 1200 NPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNN--GVCKDLVGEFICEC 1257
Query: 365 AAPELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSA 419
+ R EC S L G KGF L T +V+EC S
Sbjct: 1258 PSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET--EVNECQ-SN 1314
Query: 420 ELCAGGTCVNTDGSYRCDCPPG 441
C + G + C CPPG
Sbjct: 1315 PCLNNAVCEDQVGGFLCKCPPG 1336
Score = 37.9 bits (84), Expect = 0.073
Identities = 93/384 (24%), Positives = 129/384 (33%), Gaps = 54/384 (14%)
Query: 89 CKGGRCVNSEGSFQC-VCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECL 147
C+ G + EG +C +C +G ++ +C+ Q C+ G ++ G CE
Sbjct: 1018 CRIGSYQDEEGQLECKLCPSGMYTEYIHSR--NISDCKAQ--CKQGT-YSCSGLETCESC 1072
Query: 148 PGFTLSND--GRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVP 205
P T R+CL S A V CPEG +G + C
Sbjct: 1073 PLGTYQPKFGSRSCLSCPEN--TSTVKRGAVNISACGVPCPEGKFSRSG---LMPCHP-- 1125
Query: 206 GACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQS-YCAGGQCRNTAGSFTCV 264
CP + C+ P Y R I EC S + A + S +
Sbjct: 1126 --CPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHI 1183
Query: 265 CPEGTRHEPELQLCRD--IDECEGETETHYIESDY----ERGDIPPTFPTRTELASP--C 316
RHE Q+ + + C + Y G T + SP C
Sbjct: 1184 ---KKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPC 1240
Query: 317 -DNGRCINTHGGFECECELGYVLDATAQRCLDN----------RRGSCWRRVVDGQCEAA 365
+NG C + G F CEC GY T QRC +N +G C V +C
Sbjct: 1241 LNNGVCKDLVGEFICECPSGY----TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCV 1296
Query: 366 APELLLR-----QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALSA 419
+ L EC + L GF G C ++VDEC LS
Sbjct: 1297 KGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFL---GTRCGKNVDEC-LSQ 1352
Query: 420 ELCAGGTCVNTDGSYRCDCPPGLT 443
G TC + S+RC C G T
Sbjct: 1353 PCKNGATCKDGANSFRCLCAAGFT 1376
Score = 36.3 bits (80), Expect = 0.22
Identities = 20/75 (26%), Positives = 30/75 (40%), Gaps = 4/75 (5%)
Query: 197 DINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDM---HQSYCAGGQ 253
D++EC H SC N++ Y C C P Y D C + +C ++ + G+
Sbjct: 1748 DVDECAVGSDCSEHASCLNVDGSYICSCVPSYTGDGKN-CAEPIKCKAPGNPENGHSSGE 1806
Query: 254 CRNTAGSFTCVCPEG 268
T C EG
Sbjct: 1807 IYTVGAEVTFSCQEG 1821
Score = 31.9 bits (69), Expect = 4.8
Identities = 38/133 (28%), Positives = 47/133 (35%), Gaps = 16/133 (12%)
Query: 139 PGS-FRCECLPGFTL-SNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGA 196
PGS C PGF L N + CL G Q P + C P +NG
Sbjct: 1653 PGSKVNLFCDPGFQLVGNPVQYCLNQ----GQWTQPLP----HCERISCGVPPPLENGFH 1704
Query: 197 DINECTAVPGACPHGSCEN---LEPGYRCIC-DPGYHPDADGLCRDIDECDMHQSYCAGG 252
++ A G+ C N L R C D G C D+DEC +
Sbjct: 1705 SADDFYA--GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHA 1762
Query: 253 QCRNTAGSFTCVC 265
C N GS+ C C
Sbjct: 1763 SCLNVDGSYICSC 1775
>AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive
sequence DNA binding protein-1 protein.
Length = 1008
Score = 98.7 bits (235), Expect = 4e-20
Identities = 102/353 (28%), Positives = 142/353 (40%), Gaps = 55/353 (15%)
Query: 1 MTNGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRR-GRCRNTA 58
+ + G C NG CK G + C C P +G + + D C P C G C +
Sbjct: 198 LCSSGPCRNGGTCKEAGGEYHCSC-PYRFTGRHCEIGKP-DSCASGP--CHNGGTCFHYI 253
Query: 59 GSYTCLCEPGFAPTAAGYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGY--RPTATR 115
G Y C C PGF + YC S C GG C + + F C C+AGY R
Sbjct: 254 GKYKCDCPPGF---SGRYCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAE 310
Query: 116 GACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPA 175
C +E + + NG + C+ G++LS R + C
Sbjct: 311 VDCGPPEEVKHATLRFNGTRLGAAALYACD--RGYSLSAPSR------------IRVCQP 356
Query: 176 QGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADG 234
G + E P +I+EC + P C H GSC++ GY C+C GY
Sbjct: 357 HG------VWSEPPQ----CLEIDECRSQP--CLHGGSCQDRVAGYLCLCSTGYEGAHCE 404
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECE--GETE 289
L R DEC H GG CRN G++ C CP G E E+ C D C+ G E
Sbjct: 405 LER--DECRAHPCR-NGGSCRNLPGAYVCRCPAGFVGVHCETEVDAC-DSSPCQHGGRCE 460
Query: 290 T---HYIESDYERGDIPPTFPTRTE--LASPC-DNGRCINTHGGFECECELGY 336
+ Y+ G T ++ +SPC G C+ ++G C C++GY
Sbjct: 461 SGGGAYL-CVCPEGFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY 512
Score = 83.8 bits (198), Expect = 1e-15
Identities = 94/330 (28%), Positives = 128/330 (38%), Gaps = 58/330 (17%)
Query: 38 DVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAA--GYCADVDECAADSMCKGGRCV 95
DVD+C +P + G C + G+YTCLC F G D C + GG CV
Sbjct: 2 DVDDCSPDPCL-NGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCV 60
Query: 96 NSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN-GRCHNTPGSFRCECLPGFTLSN 154
+++ + C C G+ R D+CE CRN GRC + C+C GF
Sbjct: 61 DADQGYVCECPEGFMGLDCRERV--PDDCE----CRNGGRCLGA-NTTLCQCPLGF---- 109
Query: 155 DGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGP-SKDNGGA-------DINECTAVPG 206
GL + ++ C CP+G ++GG+ D N ++P
Sbjct: 110 -----FGLLCEFEITAMPCNMN------TQCPDGGYCMEHGGSYLCVCHTDHNASHSLPS 158
Query: 207 ACPH------GSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCA-GGQCRNTAG 259
C GSC+ + Y C C G+H C C GG C+ G
Sbjct: 159 PCNSDPCFNGGSCDAHDDSYTCECPRGFHGKH---CEKARPHLCSSGPCRNGGTCKEAGG 215
Query: 260 SFTCVCP-EGTRHEPEL---QLCRDIDECEGETETHYIESDYERGDIPPTFPTR-TELA- 313
+ C CP T E+ C G T HYI Y + D PP F R E+A
Sbjct: 216 EYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYI-GKY-KCDCPPGFSGRYCEIAP 273
Query: 314 -----SPCDN-GRCINTHGGFECECELGYV 337
SPC N G C + F C C+ GY+
Sbjct: 274 SPCFRSPCVNGGTCEDRDTDFFCHCQAGYM 303
Score = 83.4 bits (197), Expect = 1e-15
Identities = 53/146 (36%), Positives = 69/146 (47%), Gaps = 17/146 (11%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRR-GRCRNTAGSYTCLCEP 67
G C++ G+ C+C GY EGA C + DECR +P CR G CRN G+Y C C
Sbjct: 381 GSCQDRVAGYLCLCSTGY----EGAHCELERDECRAHP--CRNGGSCRNLPGAYVCRCPA 434
Query: 68 GFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV-DECE 125
GF +C +VD C + GGRC + G++ CVC G+ C V D C
Sbjct: 435 GFVGV---HCETEVDACDSSPCQHGGRCESGGGAYLCVCPEGF----FGYHCETVSDPCF 487
Query: 126 EQRVCRNGRCHNTPGSFRCECLPGFT 151
G C + GS C C G+T
Sbjct: 488 SSPCGGRGYCLASNGSHSCTCKVGYT 513
Score = 79.4 bits (187), Expect = 2e-14
Identities = 124/460 (26%), Positives = 168/460 (36%), Gaps = 64/460 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD--VDECRDNPRVCRR-GRCRNTAGSYT 62
C NG C + D G+ C C G+ G CR+ D+C CR GRC A +
Sbjct: 53 CHNGGTCVDADQGYVCECPEGF----MGLDCRERVPDDCE-----CRNGGRCLG-ANTTL 102
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C GF + C ++ C GG C+ GS+ CVC + + + + +
Sbjct: 103 CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCNS 162
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQ---ACPAQ 176
D C G C S+ CEC GF G+ C + L C+ C
Sbjct: 163 DPC-----FNGGSCDAHDDSYTCECPRGF----HGKHCEKARPHLCSSGPCRNGGTCKEA 213
Query: 177 GSELYAVLCP---EGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDA 232
G E Y CP G + G D C + G C + G+C + Y+C C PG+
Sbjct: 214 GGE-YHCSCPYRFTGRHCEIGKPD--SCAS--GPCHNGGTCFHYIGKYKCDCPPGF---- 264
Query: 233 DGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGET 288
G +I +S C GG C + F C C G R + E+ C +E + T
Sbjct: 265 SGRYCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVD-CGPPEEVKHAT 323
Query: 289 ETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDN 348
+ G R S R HG + + + + +Q CL
Sbjct: 324 LRF---NGTRLGAAALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHG 380
Query: 349 RRGSCWRRVVDGQC------EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA 402
GSC RV C E A E L R EC GS GF
Sbjct: 381 --GSCQDRVAGYLCLCSTGYEGAHCE-LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFV 437
Query: 403 KLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C +VD C S+ GG C + G+Y C CP G
Sbjct: 438 ---GVHCETEVDACD-SSPCQHGGRCESGGGAYLCVCPEG 473
Score = 71.3 bits (167), Expect = 6e-12
Identities = 88/358 (24%), Positives = 125/358 (34%), Gaps = 47/358 (13%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
G C G + C+C + + + D C + G C SYTC C GF
Sbjct: 133 GYCMEHGGSYLCVCHTDHNASHSLPSPCNSDPCFNG------GSCDAHDDSYTCECPRGF 186
Query: 70 APTAAGYC--ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
+C A C++ GG C + G + C C YR T D C
Sbjct: 187 H---GKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCP--YRFTGRHCEIGKPDSCASG 241
Query: 128 RVCRNGRCHNTPGSFRCECLPGFTLSN--------------DGRTCLGLKLGWGVSCQAC 173
G C + G ++C+C PGF+ +G TC + CQA
Sbjct: 242 PCHNGGTCFHYIGKYKCDCPPGFSGRYCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQA- 300
Query: 174 PAQGSELYA-VLCPEGPSKDNGGADINECTAVPGACPHGSCEN----LEPGYRCICDPGY 228
G A V C GP ++ A + GA +C+ P +C P
Sbjct: 301 GYMGRRCQAEVDC--GPPEEVKHATLRFNGTRLGAAALYACDRGYSLSAPSRIRVCQPHG 358
Query: 229 HPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCP---EGTRHEPELQLCRDIDECE 285
C +IDEC Q GG C++ + C+C EG E E CR C
Sbjct: 359 VWSEPPQCLEIDEC-RSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECR-AHPCR 416
Query: 286 GETETHYIESDY----ERGDIPPTFPTRTEL--ASPCDNG-RCINTHGGFECECELGY 336
+ Y G + T + +SPC +G RC + G + C C G+
Sbjct: 417 NGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPEGF 474
Score = 47.2 bits (107), Expect = 1e-04
Identities = 64/275 (23%), Positives = 96/275 (34%), Gaps = 39/275 (14%)
Query: 197 DINECTAVPGACPHG-SCENLEPGYRCIC-DPGYHPDADGLCRDIDECDMHQSYCAGGQC 254
D+++C+ P C +G SC +L Y C+C +P + + + + GG C
Sbjct: 2 DVDDCS--PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 59
Query: 255 RNTAGSFTCVCPEG------TRHEPELQLCRDIDECEGETET--------HYIESDYERG 300
+ + C CPEG P+ CR+ C G T + ++E
Sbjct: 60 VDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEIT 119
Query: 301 DIPPTFPTRTELASPCDNGRCINTHGGFECECELGY-VLDATAQRCLDN---RRGSCWRR 356
+P T+ D G C+ G + C C + + C + GSC
Sbjct: 120 AMPCNMNTQCP-----DGGYCMEHGGSYLCVCHTDHNASHSLPSPCNSDPCFNGGSCDAH 174
Query: 357 VVDGQCEAAAPELLLRQEC------CCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR 410
CE P + C CS G + + G C
Sbjct: 175 DDSYTCEC--PRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPY-RFTGRHCE 231
Query: 411 --DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
D CA S GGTC + G Y+CDCPPG +
Sbjct: 232 IGKPDSCA-SGPCHNGGTCFHYIGKYKCDCPPGFS 265
Score = 41.9 bits (94), Expect = 0.004
Identities = 62/254 (24%), Positives = 82/254 (32%), Gaps = 35/254 (13%)
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGF----TLSND---GRTCLGLKLGWGVSCQ 171
+DVD+C G C + G++ C C F + D CL G +C
Sbjct: 1 MDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC- 59
Query: 172 ACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHP 230
+ Y CPEG G D E C +G C C C G+
Sbjct: 60 ---VDADQGYVCECPEGFM----GLDCRERVPDDCECRNGGRCLGANTTL-CQCPLGFFG 111
Query: 231 DADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC--EGET 288
C+M+ GG C GS+ CVC L + D C G
Sbjct: 112 LLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCNSDPCFNGGSC 171
Query: 289 ETHYIESDYERGDIPPTF------PTRTELAS--PCDN-GRCINTHGGFECECELGYVLD 339
+ H D + P F R L S PC N G C G + C C +
Sbjct: 172 DAH---DDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRF--- 225
Query: 340 ATAQRCLDNRRGSC 353
T + C + SC
Sbjct: 226 -TGRHCEIGKPDSC 238
Score = 37.1 bits (82), Expect = 0.13
Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 412 VDECALSAELCAGGTCVNTDGSYRCDCPPG-LTLDSTGTAP 451
V + LSA GGTCV+ D Y C+CP G + LD P
Sbjct: 44 VPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP 84
>U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein.
Length = 263
Score = 98.3 bits (234), Expect = 5e-20
Identities = 83/283 (29%), Positives = 126/283 (44%), Gaps = 41/283 (14%)
Query: 19 FECICKPGYESGSEGALCRD-VDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYC 77
+ C C+ G++ G C + ++EC ++ G C + S++CLC GF +C
Sbjct: 5 YTCKCQAGFD----GVHCENNINECTESS-CFNGGTCVDGINSFSCLCPVGFT---GSFC 56
Query: 78 A-DVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRN-GRC 135
+++EC++ G CV+ G+++C C GY T C + + C+N G C
Sbjct: 57 LHEINECSSHPCLNDGTCVDGLGTYRCSCPLGY----TGKNCQTLVNLCSRSPCKNKGTC 112
Query: 136 HNTPGSFRCECLPGFT-----LSNDGRTCLGLKLGWGVS--CQ---ACPAQGSELYAVLC 185
S +C C G+ + N + G V CQ C G+ Y C
Sbjct: 113 VQKKASPQCLCPSGWVGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQ-C 171
Query: 186 PEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGL-CR-DIDEC 242
P G + ++EC + P C HG+ C + GYRC C PGY G+ C ++DEC
Sbjct: 172 PVGYTGSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQ----GVNCEYEVDEC 225
Query: 243 DMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRD-IDEC 284
+Q GG C + F C CP GTR LC + ID+C
Sbjct: 226 Q-NQPCQNGGTCIDLVNHFKCSCPPGTRG----LLCEENIDDC 263
Score = 80.2 bits (189), Expect = 1e-14
Identities = 65/240 (27%), Positives = 98/240 (40%), Gaps = 27/240 (11%)
Query: 60 SYTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC 118
SYTC C+ GF +C + ++EC S GG CV+ SF C+C G+ T C
Sbjct: 4 SYTCKCQAGFDGV---HCENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFC 56
Query: 119 V-DVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQG 177
+ +++EC +G C + G++RC C G+T N +T + L + Q
Sbjct: 57 LHEINECSSHPCLNDGTCVDGLGTYRCSCPLGYTGKN-CQTLVNLCSRSPCKNKGTCVQK 115
Query: 178 SELYAVLCPEG--------PSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGY 228
LCP G P+ A V C H G C N + C C GY
Sbjct: 116 KASPQCLCPSGWVGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPVGY 175
Query: 229 HPDADGLCRD-IDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGE 287
C + +DEC + G C + G + C C G + + ++DEC+ +
Sbjct: 176 ---TGSYCEEQLDECASNPCQ-HGATCSDFIGGYRCECVPGYQ---GVNCEYEVDECQNQ 228
Score = 66.5 bits (155), Expect = 2e-10
Identities = 40/120 (33%), Positives = 55/120 (45%), Gaps = 17/120 (14%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRD-VDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
+G+C N C C GY G+ C + +DEC NP C+ G C + G Y C C
Sbjct: 157 SGVCINAGNTHYCQCPVGYT----GSYCEEQLDECASNP--CQHGATCSDFIGGYRCECV 210
Query: 67 PGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVD--VDEC 124
PG+ Y +VDEC GG C++ F+C C P TRG + +D+C
Sbjct: 211 PGYQGVNCEY--EVDECQNQPCQNGGTCIDLVNHFKCSC-----PPGTRGLLCEENIDDC 263
Score = 63.7 bits (148), Expect = 1e-09
Identities = 43/152 (28%), Positives = 63/152 (41%), Gaps = 16/152 (10%)
Query: 7 CTN-GICKNIDGGFECICKPGYESGS---EGALCRDVDECRDNPRV---CRR-GRCRNTA 58
C N G C +C+C G+ C D+ R V C+ G C N
Sbjct: 106 CKNKGTCVQKKASPQCLCPSGWVGAYCDVPNVSC-DIAASRRGVLVEHLCQHSGVCINAG 164
Query: 59 GSYTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA 117
++ C C G+ YC + +DECA++ G C + G ++C C GY+
Sbjct: 165 NTHYCQCPVGYT---GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCE-- 219
Query: 118 CVDVDECEEQRVCRNGRCHNTPGSFRCECLPG 149
+VDEC+ Q G C + F+C C PG
Sbjct: 220 -YEVDECQNQPCQNGGTCIDLVNHFKCSCPPG 250
Score = 56.8 bits (131), Expect = 1e-07
Identities = 66/257 (25%), Positives = 95/257 (36%), Gaps = 31/257 (12%)
Query: 100 SFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTC 159
S+ C C+AG+ +++EC E G C + SF C C GFT G C
Sbjct: 4 SYTCKCQAGFDGVHCEN---NINECTESSCFNGGTCVDGINSFSCLCPVGFT----GSFC 56
Query: 160 LG-LKLGWGVSC--QACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCEN 215
L + C G Y CP G + N +N C+ P C + G+C
Sbjct: 57 LHEINECSSHPCLNDGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSP--CKNKGTCVQ 114
Query: 216 LEPGYRCICDPGY---HPDADGLCRDIDECD---MHQSYCA-GGQCRNTAGSFTCVCP-- 266
+ +C+C G+ + D + DI + + C G C N + C CP
Sbjct: 115 KKASPQCLCPSGWVGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPVG 174
Query: 267 -EGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELA------SPCDNG 319
G+ E +L C G T + +I Y +P E PC NG
Sbjct: 175 YTGSYCEEQLDECASNPCQHGATCSDFI-GGYRCECVPGYQGVNCEYEVDECQNQPCQNG 233
Query: 320 -RCINTHGGFECECELG 335
CI+ F+C C G
Sbjct: 234 GTCIDLVNHFKCSCPPG 250
Score = 42.3 bits (95), Expect = 0.003
Identities = 63/237 (26%), Positives = 87/237 (36%), Gaps = 44/237 (18%)
Query: 220 YRCICDPGYHPDADGL-CRD-IDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTR------ 270
Y C C G+ DG+ C + I+EC +S C GG C + SF+C+CP G
Sbjct: 5 YTCKCQAGF----DGVHCENNINECT--ESSCFNGGTCVDGINSFSCLCPVGFTGSFCLH 58
Query: 271 --HEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELAS--PCDN-GRCINTH 325
+E C + C T+ G T L S PC N G C+
Sbjct: 59 EINECSSHPCLNDGTCVDGLGTYRCSCPL--GYTGKNCQTLVNLCSRSPCKNKGTCVQKK 116
Query: 326 GGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSVGLAWGS 385
+C C G+V + V + C+ AA + E C G
Sbjct: 117 ASPQCLCPSGWV--------------GAYCDVPNVSCDIAASRRGVLVEHLCQHS---GV 159
Query: 386 XXXXXXXXXXXXXKGFAKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G+ G+ C + +DECA S G TC + G YRC+C PG
Sbjct: 160 CINAGNTHYCQCPVGYT---GSYCEEQLDECA-SNPCQHGATCSDFIGGYRCECVPG 212
Score = 35.9 bits (79), Expect = 0.29
Identities = 17/39 (43%), Positives = 24/39 (61%), Gaps = 2/39 (5%)
Query: 406 GATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
G+ C +++EC+ S GTCV+ G+YRC CP G T
Sbjct: 53 GSFCLHEINECS-SHPCLNDGTCVDGLGTYRCSCPLGYT 90
Score = 35.9 bits (79), Expect = 0.29
Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 2/37 (5%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
G C +VDEC + GGTC++ ++C CPPG
Sbjct: 215 GVNCEYEVDECQ-NQPCQNGGTCIDLVNHFKCSCPPG 250
Score = 35.1 bits (77), Expect = 0.51
Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 402 AKLDGATCRD-VDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
A DG C + ++EC S+ GGTCV+ S+ C CP G T
Sbjct: 11 AGFDGVHCENNINECTESS-CFNGGTCVDGINSFSCLCPVGFT 52
>AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.
Length = 1282
Score = 97.1 bits (231), Expect = 1e-19
Identities = 109/366 (29%), Positives = 149/366 (40%), Gaps = 54/366 (14%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRG-RCRNTAGSYTCL 64
C NG C D + C C G+ G R C P CR G C+ G Y C
Sbjct: 419 CFNGGSCDAHDDSYTCECPRGFH-GKHCEKARP-HLCSSGP--CRNGGTCKEAGGEYHCS 474
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR-------PTAT-RG 116
C F D CA+ GG C + G ++C C G+ P+ R
Sbjct: 475 CPYRFTGRHCEI-GKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRS 533
Query: 117 ACVDVDECEEQRVCRNGRCHNTPGSF--RCE----CLPGFTLSNDGRTCLGLKLGWGVSC 170
CV+ CE++ + CH G RC+ C P + + G +LG V+
Sbjct: 534 PCVNGGTCEDRDT--DFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLG-AVAL 590
Query: 171 QACPAQGSELYA-----VLCPEGP-SKDNGGADINECTAVPGACPHG-SCENLEPGYRCI 223
AC +G L A V P G S+ +I+EC + P C HG SC++ GY C+
Sbjct: 591 YACD-RGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQP--CLHGGSCQDRVAGYLCL 647
Query: 224 CDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPE---GTRHEPELQLCRD 280
C GY L RD EC H GG CRN G++ C CP G E E+ C D
Sbjct: 648 CSTGYEGAHCELERD--ECRAHPCR-NGGSCRNLPGAYVCRCPAGFVGVHCETEVDAC-D 703
Query: 281 IDECE--GETET---HYI----ESDYERGDIPPTFPTRTELASPC-DNGRCINTHGGFEC 330
C+ G E+ Y+ ES + + P +SPC G C+ ++G C
Sbjct: 704 SSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPC---FSSPCGGRGYCLASNGSHSC 760
Query: 331 ECELGY 336
C++GY
Sbjct: 761 TCKVGY 766
Score = 91.5 bits (217), Expect = 6e-18
Identities = 106/377 (28%), Positives = 135/377 (35%), Gaps = 59/377 (15%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGS 60
NGG C + C + + C C G+ G C DV+EC P C+ G C + S
Sbjct: 149 NGGKCIDD-CVTGNPSYTCSCLSGFT----GRRCHLDVNECASQP--CQNGGTCTHGINS 201
Query: 61 YTCLCEPGFA----PTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG 116
+ C C GF TA C D EC GG+C GS CVC+AGY T
Sbjct: 202 FRCQCPAGFGGPTCETAQSPC-DTKECQ-----HGGQCQVENGSAVCVCQAGY----TGA 251
Query: 117 AC-VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFT----LSNDGRT---CLGLKLGWGV 168
AC +DVD+C G C + G++ C C F + D CL G
Sbjct: 252 ACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGG 311
Query: 169 SCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPG 227
+C + Y CPEG G D E C +G C C C G
Sbjct: 312 TC----VDADQGYVCECPEGFM----GLDCRERVPDDCECRNGGRCLGANTTL-CQCPLG 362
Query: 228 YHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDEC--E 285
+ C+M+ GG C GS+ CVC L D D C
Sbjct: 363 FFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNG 422
Query: 286 GETETHYIESDYERGDIPPTF------PTRTELAS--PCDN-GRCINTHGGFECECELGY 336
G + H D + P F R L S PC N G C G + C C +
Sbjct: 423 GSCDAH---DDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRF 479
Query: 337 VLDATAQRCLDNRRGSC 353
T + C + SC
Sbjct: 480 ----TGRHCEIGKPDSC 492
Score = 81.4 bits (192), Expect = 6e-15
Identities = 54/147 (36%), Positives = 70/147 (47%), Gaps = 19/147 (12%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRG-RCRNTAGSYTCLCEP 67
G C++ G+ C+C GYE GA C + DECR +P CR G CRN G+Y C C
Sbjct: 635 GSCQDRVAGYLCLCSTGYE----GAHCELERDECRAHP--CRNGGSCRNLPGAYVCRCPA 688
Query: 68 GFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDV-DEC 124
GF +C +VD C + GGRC + G++ CVC P + G C V D C
Sbjct: 689 GFVGV---HCETEVDACDSSPCQHGGRCESGGGAYLCVC-----PESFFGYHCETVSDPC 740
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFT 151
G C + GS C C G+T
Sbjct: 741 FSSPCGGRGYCLASNGSHSCTCKVGYT 767
Score = 80.6 bits (190), Expect = 1e-14
Identities = 122/458 (26%), Positives = 166/458 (36%), Gaps = 64/458 (13%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALCRD--VDECRDNPRVCRRG-RCRNTAGSYT 62
C NG C + D G+ C C G+ G CR+ D+C CR G RC A +
Sbjct: 307 CHNGGTCVDADQGYVCECPEGFM----GLDCRERVPDDCE-----CRNGGRCLG-ANTTL 356
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C C GF + C ++ C GG C+ GS+ CVC + + + + D
Sbjct: 357 CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDS 416
Query: 122 DECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK--LGWGVSCQ---ACPAQ 176
D C G C S+ CEC GF G+ C + L C+ C
Sbjct: 417 DPC-----FNGGSCDAHDDSYTCECPRGF----HGKHCEKARPHLCSSGPCRNGGTCKEA 467
Query: 177 GSELYAVLCP---EGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDA 232
G E Y CP G + G D C + G C +G +C + Y+C C PG+
Sbjct: 468 GGE-YHCSCPYRFTGRHCEIGKPD--SCAS--GPCHNGGTCFHYIGKYKCDCPPGF---- 518
Query: 233 DGLCRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLCRDIDECEGETETH 291
G +I +S C GG C + F C C G + C+ +C E
Sbjct: 519 SGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMG----RRCQAEVDCGPPEEVK 574
Query: 292 YIESDYER---GDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDN 348
+ + G + R S R HG + + + + +Q CL
Sbjct: 575 HATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHG 634
Query: 349 RRGSCWRRVVDGQC------EAAAPELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFA 402
GSC RV C E A EL R EC GS GF
Sbjct: 635 --GSCQDRVAGYLCLCSTGYEGAHCELE-RDECRAHPCRNGGSCRNLPGAYVCRCPAGFV 691
Query: 403 KLDGATCR-DVDECALSAELCAGGTCVNTDGSYRCDCP 439
G C +VD C S+ GG C + G+Y C CP
Sbjct: 692 ---GVHCETEVDACD-SSPCQHGGRCESGGGAYLCVCP 725
Score = 79.8 bits (188), Expect = 2e-14
Identities = 97/398 (24%), Positives = 141/398 (35%), Gaps = 50/398 (12%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C + C C CV S+ C C +G+ R +DV+EC Q G C
Sbjct: 141 CLALRPCLNGGKCIDD-CVTGNPSYTCSCLSGF---TGRRCHLDVNECASQPCQNGGTCT 196
Query: 137 NTPGSFRCECLPGF---TLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDN 193
+ SFRC+C GF T C + G CQ GS + +C G +
Sbjct: 197 HGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQV--ENGSAV--CVCQAGYTGAA 252
Query: 194 GGADINECTAVPGACPHG-SCENLEPGYRCIC-DPGYHPDADGLCRDIDECDMHQSYCAG 251
D+++C+ P C +G SC +L Y C+C +P + + + + G
Sbjct: 253 CEMDVDDCS--PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNG 310
Query: 252 GQCRNTAGSFTCVCPEG------TRHEPELQLCRDIDECEGETET--------HYIESDY 297
G C + + C CPEG P+ CR+ C G T + ++
Sbjct: 311 GTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEF 370
Query: 298 ERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRCLDN----RRGSC 353
E +P T+ D G C+ G + C C + + D+ GSC
Sbjct: 371 EITAMPCNMNTQCP-----DGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSC 425
Query: 354 WRRVVDGQCEAAAPELLLRQEC------CCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGA 407
CE P + C CS G + + G
Sbjct: 426 DAHDDSYTCEC--PRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPY-RFTGR 482
Query: 408 TCR--DVDECALSAELCAGGTCVNTDGSYRCDCPPGLT 443
C D CA S GGTC + G Y+CDCPPG +
Sbjct: 483 HCEIGKPDSCA-SGPCHNGGTCFHYIGKYKCDCPPGFS 519
Score = 68.5 bits (160), Expect = 5e-11
Identities = 74/291 (25%), Positives = 112/291 (38%), Gaps = 47/291 (16%)
Query: 5 GMCTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTC 63
G C NG C + G ++C C PG+ SG + C +P V G C + + C
Sbjct: 495 GPCHNGGTCFHYIGKYKCDCPPGF-SGRHCEIA--PSPCFRSPCV-NGGTCEDRDTDFFC 550
Query: 64 LCEPGFAP---TAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGY---RPTATR-- 115
C+ G+ A C +E ++ G + + + C+ GY P+ R
Sbjct: 551 HCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALY--ACDRGYSLSAPSRIRVC 608
Query: 116 ---------GACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTCLGLK 163
C+++DEC Q G C + + C C G+ ++ + C
Sbjct: 609 QPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP 668
Query: 164 LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRC 222
G SC+ P Y CP G + +++ C + P C HG CE+ Y C
Sbjct: 669 CRNGGSCRNLPG----AYVCRCPAGFVGVHCETEVDACDSSP--CQHGGRCESGGGAYLC 722
Query: 223 ICDP---GYHPDADGLCRDI-DECDMHQSYCAG-GQCRNTAGSFTCVCPEG 268
+C GYH C + D C S C G G C + GS +C C G
Sbjct: 723 VCPESFFGYH------CETVSDPC--FSSPCGGRGYCLASNGSHSCTCKVG 765
Score = 62.1 bits (144), Expect = 4e-09
Identities = 123/491 (25%), Positives = 177/491 (36%), Gaps = 91/491 (18%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGRCRNTAGSYTCLC--- 65
G C+ +G C+C+ GY GA C DVD+C +P + G C + G+YTCLC
Sbjct: 231 GQCQVENGSAVCVCQAGYT----GAACEMDVDDCSPDPCL-NGGSCVDLVGNYTCLCAEP 285
Query: 66 ------EPGFAPTA----------AGYCADVD-----ECAA-------------DSMCK- 90
E G P G C D D EC D C+
Sbjct: 286 FKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRN 345
Query: 91 GGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGR-CHNTPGSFRCECLPG 149
GGRC+ + + C C G+ + C C +G C GS+ C C
Sbjct: 346 GGRCLGANTTL-CQCPLGFFGLLCEFE-ITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTD 403
Query: 150 FTLSND-GRTCLGLKLGWGVSCQACPAQGSELYAVLCPEG-PSKDNGGADINECTAVPGA 207
S+ C G SC A + Y CP G K A + C++ G
Sbjct: 404 HNASHSLPSPCDSDPCFNGGSCDA----HDDSYTCECPRGFHGKHCEKARPHLCSS--GP 457
Query: 208 CPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCP 266
C +G +C+ Y C C + + + D C + GG C + G + C CP
Sbjct: 458 CRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKP-DSCASGPCH-NGGTCFHYIGKYKCDCP 515
Query: 267 EGT--RH-----EPELQL-CRDIDECEGETETHYI--ESDYE----RGDIPPTFPTRTEL 312
G RH P + C + CE + ++ Y + ++ P +
Sbjct: 516 PGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKH 575
Query: 313 ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLR 372
A+ NG + + C+ GY L A ++ + G W + P+ L
Sbjct: 576 ATLRFNGTRLGAVALYACD--RGYSLSAPSRIRVCQPHG-VW---------SEPPQCLEI 623
Query: 373 QECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCR-DVDECALSAELCA-GGTCVNT 430
EC L GS G+ +GA C + DEC A C GG+C N
Sbjct: 624 DECRSQPCLHGGSCQDRVAGYLCLCSTGY---EGAHCELERDECR--AHPCRNGGSCRNL 678
Query: 431 DGSYRCDCPPG 441
G+Y C CP G
Sbjct: 679 PGAYVCRCPAG 689
Score = 43.2 bits (97), Expect = 0.002
Identities = 58/198 (29%), Positives = 72/198 (36%), Gaps = 28/198 (14%)
Query: 260 SFTCVCPEG---TRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTF--PTRTELAS 314
S+TC C G R ++ C G T TH I S R P F PT S
Sbjct: 163 SYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSF--RCQCPAGFGGPTCETAQS 220
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
PCD C HGG +C+ E G + C G+ VD C +P+ L
Sbjct: 221 PCDTKEC--QHGG-QCQVENGSAVCV----CQAGYTGAACEMDVD-DC---SPDPCLNGG 269
Query: 375 CCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSY 434
C + KG G V + LSA GGTCV+ D Y
Sbjct: 270 SCVDL-------VGNYTCLCAEPFKGLRCETGD--HPVPDACLSAPCHNGGTCVDADQGY 320
Query: 435 RCDCPPG-LTLDSTGTAP 451
C+CP G + LD P
Sbjct: 321 VCECPEGFMGLDCRERVP 338
>U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homolog
mRNA, partial cds. ).
Length = 446
Score = 96.3 bits (229), Expect = 2e-19
Identities = 69/209 (33%), Positives = 88/209 (42%), Gaps = 24/209 (11%)
Query: 74 AGYCADVDECAADS-MCKGGR-CVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-QRVC 130
+ YC D+DECAA C CVN G ++C C GY +C + DEC Q C
Sbjct: 47 SAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYI-RVDDFSCTEHDECGSGQHNC 105
Query: 131 -RNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA---VLCP 186
N C NT C C PG+ +G C C+ G A +CP
Sbjct: 106 DENAICTNTVQGHSCTCKPGYV--GNGTICRAF-------CEEGCRYGGTCVAPNKCVCP 156
Query: 187 EGPSKDNGGADINECTAVPGACP-HGSCENLEPGYRCICDPGYHPD-----ADGLCRDID 240
G + + DI+EC+ C H C NL + C C G+H D + C DID
Sbjct: 157 SGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWHHCECRSGFHDDGTYSLSGESCIDID 216
Query: 241 ECDMHQSYCAGGQ-CRNTAGSFTCVCPEG 268
EC + C C N AG F C+CP G
Sbjct: 217 ECALRTHTCWNDSACINLAGGFDCLCPCG 245
Score = 82.6 bits (195), Expect = 3e-15
Identities = 78/258 (30%), Positives = 104/258 (40%), Gaps = 41/258 (15%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVC-RRGRCRNTAGSYTCLCEP 67
N +C N+ G + C C PGY + + C + DEC C C NT ++C C+P
Sbjct: 66 NTVCVNLPGLYRCDCVPGYIRVDDFS-CTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 124
Query: 68 GFAPTAAGYCADVDECAADSMCK-GGRCVNSEGSFQCVCEAGYRPTATRGAC-VDVDECE 125
G+ + + C+ GG CV +CVC +G+ T C D+DEC
Sbjct: 125 GYVGNGT-----ICRAFCEEGCRYGGTCVAPN---KCVCPSGF----TGSHCEKDIDECS 172
Query: 126 EQRV-CRN-GRCHNTPGSFRCECLPGF----TLSNDGRTCLGL-------KLGWGVSCQA 172
E + C N RC N PG CEC GF T S G +C+ + W S
Sbjct: 173 EGIIECHNHSRCVNLPGWHHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACI 232
Query: 173 CPAQGSELYAVLCPEGPS-----KDNGGADIN--ECTAVPGACPHGSCENLEPGYRCICD 225
A G + LCP GPS GG N T C SC++ + R
Sbjct: 233 NLAGG---FDCLCPCGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTAC 289
Query: 226 PGYHPDADGLCRDIDECD 243
+P AD C ECD
Sbjct: 290 DCQNPSADLFC--CPECD 305
Score = 66.9 bits (156), Expect = 1e-10
Identities = 65/220 (29%), Positives = 85/220 (38%), Gaps = 22/220 (10%)
Query: 29 SGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGFAPTAAGYCADVDEC-AAD 86
S + A C D+DEC C C N G Y C C PG+ C + DEC +
Sbjct: 43 SRGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQ 102
Query: 87 SMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCE 145
C + C N+ C C+ GY T C CEE CR G P +C
Sbjct: 103 HNCDENAICTNTVQGHSCTCKPGYVGNGT--ICRAF--CEEG--CRYGGTCVAPN--KCV 154
Query: 146 CLPGFTLSN---DGRTCLG--LKLGWGVSCQACPA-QGSELYAVLCPEGPSKDNGGA--D 197
C GFT S+ D C ++ C P E + +G +G + D
Sbjct: 155 CPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWHHCECRSGFHDDGTYSLSGESCID 214
Query: 198 INECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLC 236
I+EC C + S C NL G+ C+C G P G C
Sbjct: 215 IDECALRTHTCWNDSACINLAGGFDCLCPCG--PSCSGDC 252
Score = 60.9 bits (141), Expect = 9e-09
Identities = 53/186 (28%), Positives = 74/186 (39%), Gaps = 14/186 (7%)
Query: 118 CVDVDECE-EQRVCR-NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQACP 174
C D+DEC + C N C N PG +RC+C+PG+ +D + G G +C
Sbjct: 50 CEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENA 109
Query: 175 AQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
+ + C P G I G G+C + P +C+C G+
Sbjct: 110 ICTNTVQGHSCTCKPGYVGNGT-ICRAFCEEGCRYGGTC--VAPN-KCVCPSGF--TGSH 163
Query: 235 LCRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEGTRHEPELQL----CRDIDECEGETE 289
+DIDEC C +C N G C C G + L C DIDEC T
Sbjct: 164 CEKDIDECSEGIIECHNHSRCVNLPGWHHCECRSGFHDDGTYSLSGESCIDIDECALRTH 223
Query: 290 THYIES 295
T + +S
Sbjct: 224 TCWNDS 229
Score = 50.8 bits (116), Expect = 1e-05
Identities = 21/38 (55%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPG 441
D A C D+DECA C T CVN G YRCDC PG
Sbjct: 46 DSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPG 83
Score = 43.2 bits (97), Expect = 0.002
Identities = 43/146 (29%), Positives = 53/146 (36%), Gaps = 25/146 (17%)
Query: 316 CD-NGRCINTHGGFECECELGYVLDATAQR--CLDNRR--GSCWRRVVDGQCEAAAPELL 370
CD N C NT G C C+ GYV + T R C + R G+C V +C P
Sbjct: 105 CDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTC---VAPNKC--VCPSGF 159
Query: 371 LRQECC-----CSVGLAWGSXXXXXXXX---------XXXXXKGFAKLDGATCRDVDECA 416
C CS G+ G L G +C D+DECA
Sbjct: 160 TGSHCEKDIDECSEGIIECHNHSRCVNLPGWHHCECRSGFHDDGTYSLSGESCIDIDECA 219
Query: 417 LSAELC-AGGTCVNTDGSYRCDCPPG 441
L C C+N G + C CP G
Sbjct: 220 LRTHTCWNDSACINLAGGFDCLCPCG 245
Score = 35.5 bits (78), Expect = 0.39
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDST 447
G+ ++D +C + DEC C C NT + C C PG + T
Sbjct: 83 GYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 131
Score = 32.7 bits (71), Expect = 2.7
Identities = 35/144 (24%), Positives = 51/144 (35%), Gaps = 19/144 (13%)
Query: 318 NGRCINTHGGFECECELGYV----LDATAQRCLDNRRGSC-----WRRVVDGQCEAAAPE 368
N C+N G + C+C GY+ T + + +C V G P
Sbjct: 66 NTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPG 125
Query: 369 LLLRQECC---CSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATC-RDVDECALSAELCAG 424
+ C C G +G GF G+ C +D+DEC+ C
Sbjct: 126 YVGNGTICRAFCEEGCRYGGTCVAPNKCVCPS--GFT---GSHCEKDIDECSEGIIECHN 180
Query: 425 GT-CVNTDGSYRCDCPPGLTLDST 447
+ CVN G + C+C G D T
Sbjct: 181 HSRCVNLPGWHHCECRSGFHDDGT 204
>AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precursor
protein.
Length = 1406
Score = 96.3 bits (229), Expect = 2e-19
Identities = 99/376 (26%), Positives = 148/376 (39%), Gaps = 58/376 (15%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
GIC CIC GY G C D DEC +P C+ G C++ Y+C C P
Sbjct: 123 GICHQDPIYPVCICPAGYA----GRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVP 176
Query: 68 GFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G+ +C +VDECA+D C+N G + C+C Y +++DEC
Sbjct: 177 GYQ---GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE---LEIDECWS 230
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCP 186
Q C + G++ C+C PGF G C ++ C +Q L+ LC
Sbjct: 231 QPCLNGATCQDALGAYFCDCAPGFL----GDHC-------ELNTDECASQPC-LHGGLCV 278
Query: 187 EGPSK-----DNGGADINECTAVPGAC------PHGSCENLEPGYRCICDPGYHPDADGL 235
+G ++ G C + C + +CE+ Y C C PGY
Sbjct: 279 DGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY---TGAQ 335
Query: 236 CR-DIDECDMHQSYCAGGQC-----RNTAGSFTCVCPEGTRHEPELQLCRDIDECEG--- 286
C D++EC+ + + G+C G T + + HE +C G
Sbjct: 336 CEIDLNECNSNPCQ-SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC 394
Query: 287 ETETHYIESD-YERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
E + + S+ + G P P DN +GG +C +L T Q+C
Sbjct: 395 EEDVNECSSNPCQNGGTCENLPGNYTCHCPFDN-LSRTFYGGRDCS---DILLGCTHQQC 450
Query: 346 LDNRRGSCWRRVVDGQ 361
L+N G+C DGQ
Sbjct: 451 LNN--GTCIPHFQDGQ 464
Score = 90.6 bits (215), Expect = 1e-17
Identities = 85/285 (29%), Positives = 122/285 (42%), Gaps = 36/285 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDV-DECRDNPRVCR-RGRCRNTAG--SYTCL 64
N CK+ +C C + + C ++ D C NP C+ C NT G S+ C
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKD--CDNMKDPCFSNP--CQGSATCVNTPGERSFLCK 97
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C PG++ T + C +S GG C C+C AGY A R +D DEC
Sbjct: 98 CPPGYSGTICE--TTIGSCGKNSCQHGGICHQDPIYPVCICPAGY---AGRFCEIDHDEC 152
Query: 125 EEQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--- 180
C+NG C + + C C+PG+ GR C L++ S C + + L
Sbjct: 153 ASS-PCQNGAVCQDGIDGYSCFCVPGY----QGRHC-DLEVDECAS-DPCKNEATCLNEI 205
Query: 181 --YAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCR 237
Y +CP S N +I+EC + P C +G +C++ Y C C PG+ D L
Sbjct: 206 GRYTCICPHNYSGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCEL-- 261
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCP----EGTRHEPELQLC 278
+ DEC Q GG C + ++C C GT E + LC
Sbjct: 262 NTDEC-ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC 305
Score = 81.4 bits (192), Expect = 6e-15
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C +G C++I + C C G+ SG L ++DEC NP C G C + +Y
Sbjct: 1144 NSNPCLHGGNCEDIYSSYHCSCPLGW-SGKHCEL--NIDECFSNP--CIHGNCSDRVAAY 1198
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C CEPG+ T D+D C + G C++ + C+C + R + +
Sbjct: 1199 HCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 122 DECEEQR---VCRN-GRCHNTPGSFRCECLPGFT 151
C ++ C N G C +C C PGFT
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Score = 79.0 bits (186), Expect = 3e-14
Identities = 102/364 (28%), Positives = 137/364 (37%), Gaps = 57/364 (15%)
Query: 122 DECEEQRVCRNGRCHNTPG--SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGS 178
D C + C NTPG SF C+C PG++ T +G G SCQ
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFLCKCPPGYS-GTICETTIG-SCGKN-SCQHGGICHQD 128
Query: 179 ELYAV-LCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLC 236
+Y V +CP G + D +EC + P C +G+ C++ GY C C PGY L
Sbjct: 129 PIYPVCICPAGYAGRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDL- 185
Query: 237 RDIDECDMHQSYCAG-GQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHY 292
++DEC C C N G +TC+CP G E E+ C G T
Sbjct: 186 -EVDECASDP--CKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDA 242
Query: 293 IES---DYERGDIPPTFPTRT-ELAS-PC-DNGRCINTHGGFECECE-LGYV-------- 337
+ + D G + T E AS PC G C++ + C C G+
Sbjct: 243 LGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLM 302
Query: 338 ---------LDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-----ECC-CSVGLA 382
+AT + +DN CW QCE E EC S
Sbjct: 303 PLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 362
Query: 383 WGSXXXXXXXXXXXXXKGFAKL-----DGATCR-DVDECALSAELCA-GGTCVNTDGSYR 435
+G G+ + G C DV+EC S+ C GGTC N G+Y
Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNEC--SSNPCQNGGTCENLPGNYT 420
Query: 436 CDCP 439
C CP
Sbjct: 421 CHCP 424
Score = 70.1 bits (164), Expect = 1e-11
Identities = 54/206 (26%), Positives = 89/206 (43%), Gaps = 28/206 (13%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRC 94
C ++ C NP + G C + SY C C G++ +C ++DEC ++ C G C
Sbjct: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWS---GKHCELNIDECFSNP-CIHGNC 1191
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN 154
+ ++ C CE GY VD+D C+ + C + + C C FT
Sbjct: 1192 SDRVAAYHCTCEPGYTGVNCE---VDIDNCQSHQCANGATCISHTNGYSCLCFGNFT--- 1245
Query: 155 DGRTCLGLKLGWGV--------SCQA---CPAQGSELYAVLCPEGPSKDNGGADINECTA 203
G+ C +L V +C C +EL +C G + + DI+EC +
Sbjct: 1246 -GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGEWCEKDIDECAS 1303
Query: 204 VPGACPHGS-CENLEPGYRCICDPGY 228
P C +G C++L ++C+CD +
Sbjct: 1304 DP--CVNGGLCQDLLNKFQCLCDVAF 1327
Score = 65.7 bits (153), Expect = 3e-10
Identities = 51/200 (25%), Positives = 83/200 (41%), Gaps = 24/200 (12%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C ++ C ++ GG C + S+ C C G+ + + +++DEC C +G C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNPCIHGNCS 1192
Query: 137 NTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSC------QACPAQGSELYAVLCPE 187
+ ++ C C PG+T N D C + G +C +C G+ C +
Sbjct: 1193 DRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGN-FTGKFCRQ 1251
Query: 188 G--PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
PS G N T G G+C + +C+C PG+ + +DIDEC
Sbjct: 1252 SRLPSTVCGNEKTN-LTCYNG----GNCTEFQTELKCMCRPGF--TGEWCEKDIDEC-AS 1303
Query: 246 QSYCAGGQCRNTAGSFTCVC 265
GG C++ F C+C
Sbjct: 1304 DPCVNGGLCQDLLNKFQCLC 1323
Score = 61.3 bits (142), Expect = 7e-09
Identities = 52/172 (30%), Positives = 70/172 (40%), Gaps = 37/172 (21%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCR-RGRC------------ 54
N C++ + C C PGY GA C D++EC NP C+ G C
Sbjct: 313 NATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSNP--CQSNGECVELSSEKQYGRI 366
Query: 55 --------RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCE 106
+ A Y C+C+PGF T DV+EC+++ GG C N G++ C C
Sbjct: 367 TGLPSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424
Query: 107 AGYRPTATRGA--CVDV-DECEEQRVCRNGRC--HNTPG--SFRCECLPGFT 151
G C D+ C Q+ NG C H G F C C G+T
Sbjct: 425 FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
Score = 53.6 bits (123), Expect = 1e-06
Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 16/112 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDV----DEC---RDNPRVCRRGRCRNTA 58
C NG C + G+ C+C + G CR C + N G C
Sbjct: 1223 CANGATCISHTNGYSCLCFGNFT----GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQ 1278
Query: 59 GSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGY 109
C+C PGF +C D+DECA+D GG C + FQC+C+ +
Sbjct: 1279 TELKCMCRPGFT---GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 45.6 bits (103), Expect = 4e-04
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 7/66 (10%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C +C+C+PG+ G C +D+DEC +P V G C++ + CL
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGF----TGEWCEKDIDECASDPCV-NGGLCQDLLNKFQCL 1322
Query: 65 CEPGFA 70
C+ FA
Sbjct: 1323 CDVAFA 1328
Score = 42.3 bits (95), Expect = 0.003
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 12/94 (12%)
Query: 194 GGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGG 252
G +N C + P C HG +CE++ Y C C G+ L +IDEC + C G
Sbjct: 1136 GCLQLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGWSGKHCEL--NIDEC--FSNPCIHG 1189
Query: 253 QCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECE 285
C + ++ C C G T E+ DID C+
Sbjct: 1190 NCSDRVAAYHCTCEPGYTGVNCEV----DIDNCQ 1219
Score = 35.1 bits (77), Expect = 0.51
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G C ++DEC S G TC + G+Y CDC PG D
Sbjct: 218 GVNCELEIDEC-WSQPCLNGATCQDALGAYFCDCAPGFLGD 257
Score = 31.5 bits (68), Expect = 6.3
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 115 RGACVDVDECEEQRVCRNGRCHNTPGSFRCEC 146
+ CV D CE Q GRC N S++C+C
Sbjct: 667 KAGCVRKDWCESQPCQSRGRCINLWLSYQCDC 698
Score = 31.1 bits (67), Expect = 8.4
Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 409 CRDVDECALSAELCAGGTCVNTDG--SYRCDCPPG 441
C ++ + S TCVNT G S+ C CPPG
Sbjct: 67 CDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
>AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precursor
protein.
Length = 1376
Score = 96.3 bits (229), Expect = 2e-19
Identities = 99/376 (26%), Positives = 148/376 (39%), Gaps = 58/376 (15%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
GIC CIC GY G C D DEC +P C+ G C++ Y+C C P
Sbjct: 123 GICHQDPIYPVCICPAGYA----GRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVP 176
Query: 68 GFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G+ +C +VDECA+D C+N G + C+C Y +++DEC
Sbjct: 177 GYQ---GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE---LEIDECWS 230
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCP 186
Q C + G++ C+C PGF G C ++ C +Q L+ LC
Sbjct: 231 QPCLNGATCQDALGAYFCDCAPGFL----GDHC-------ELNTDECASQPC-LHGGLCV 278
Query: 187 EGPSK-----DNGGADINECTAVPGAC------PHGSCENLEPGYRCICDPGYHPDADGL 235
+G ++ G C + C + +CE+ Y C C PGY
Sbjct: 279 DGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY---TGAQ 335
Query: 236 CR-DIDECDMHQSYCAGGQC-----RNTAGSFTCVCPEGTRHEPELQLCRDIDECEG--- 286
C D++EC+ + + G+C G T + + HE +C G
Sbjct: 336 CEIDLNECNSNPCQ-SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC 394
Query: 287 ETETHYIESD-YERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
E + + S+ + G P P DN +GG +C +L T Q+C
Sbjct: 395 EEDVNECSSNPCQNGGTCENLPGNYTCHCPFDN-LSRTFYGGRDCS---DILLGCTHQQC 450
Query: 346 LDNRRGSCWRRVVDGQ 361
L+N G+C DGQ
Sbjct: 451 LNN--GTCIPHFQDGQ 464
Score = 90.6 bits (215), Expect = 1e-17
Identities = 85/285 (29%), Positives = 122/285 (42%), Gaps = 36/285 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDV-DECRDNPRVCR-RGRCRNTAG--SYTCL 64
N CK+ +C C + + C ++ D C NP C+ C NT G S+ C
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKD--CDNMKDPCFSNP--CQGSATCVNTPGERSFLCK 97
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C PG++ T + C +S GG C C+C AGY A R +D DEC
Sbjct: 98 CPPGYSGTICE--TTIGSCGKNSCQHGGICHQDPIYPVCICPAGY---AGRFCEIDHDEC 152
Query: 125 EEQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--- 180
C+NG C + + C C+PG+ GR C L++ S C + + L
Sbjct: 153 ASS-PCQNGAVCQDGIDGYSCFCVPGY----QGRHC-DLEVDECAS-DPCKNEATCLNEI 205
Query: 181 --YAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCR 237
Y +CP S N +I+EC + P C +G +C++ Y C C PG+ D L
Sbjct: 206 GRYTCICPHNYSGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCEL-- 261
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCP----EGTRHEPELQLC 278
+ DEC Q GG C + ++C C GT E + LC
Sbjct: 262 NTDEC-ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC 305
Score = 81.4 bits (192), Expect = 6e-15
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C +G C++I + C C G+ SG L ++DEC NP C G C + +Y
Sbjct: 1144 NSNPCLHGGNCEDIYSSYHCSCPLGW-SGKHCEL--NIDECFSNP--CIHGNCSDRVAAY 1198
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C CEPG+ T D+D C + G C++ + C+C + R + +
Sbjct: 1199 HCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 122 DECEEQR---VCRN-GRCHNTPGSFRCECLPGFT 151
C ++ C N G C +C C PGFT
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Score = 79.0 bits (186), Expect = 3e-14
Identities = 102/364 (28%), Positives = 137/364 (37%), Gaps = 57/364 (15%)
Query: 122 DECEEQRVCRNGRCHNTPG--SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGS 178
D C + C NTPG SF C+C PG++ T +G G SCQ
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFLCKCPPGYS-GTICETTIG-SCGKN-SCQHGGICHQD 128
Query: 179 ELYAV-LCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLC 236
+Y V +CP G + D +EC + P C +G+ C++ GY C C PGY L
Sbjct: 129 PIYPVCICPAGYAGRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDL- 185
Query: 237 RDIDECDMHQSYCAG-GQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHY 292
++DEC C C N G +TC+CP G E E+ C G T
Sbjct: 186 -EVDECASDP--CKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDA 242
Query: 293 IES---DYERGDIPPTFPTRT-ELAS-PC-DNGRCINTHGGFECECE-LGYV-------- 337
+ + D G + T E AS PC G C++ + C C G+
Sbjct: 243 LGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLM 302
Query: 338 ---------LDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-----ECC-CSVGLA 382
+AT + +DN CW QCE E EC S
Sbjct: 303 PLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 362
Query: 383 WGSXXXXXXXXXXXXXKGFAKL-----DGATCR-DVDECALSAELCA-GGTCVNTDGSYR 435
+G G+ + G C DV+EC S+ C GGTC N G+Y
Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNEC--SSNPCQNGGTCENLPGNYT 420
Query: 436 CDCP 439
C CP
Sbjct: 421 CHCP 424
Score = 70.1 bits (164), Expect = 1e-11
Identities = 54/206 (26%), Positives = 89/206 (43%), Gaps = 28/206 (13%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRC 94
C ++ C NP + G C + SY C C G++ +C ++DEC ++ C G C
Sbjct: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWS---GKHCELNIDECFSNP-CIHGNC 1191
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN 154
+ ++ C CE GY VD+D C+ + C + + C C FT
Sbjct: 1192 SDRVAAYHCTCEPGYTGVNCE---VDIDNCQSHQCANGATCISHTNGYSCLCFGNFT--- 1245
Query: 155 DGRTCLGLKLGWGV--------SCQA---CPAQGSELYAVLCPEGPSKDNGGADINECTA 203
G+ C +L V +C C +EL +C G + + DI+EC +
Sbjct: 1246 -GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGEWCEKDIDECAS 1303
Query: 204 VPGACPHGS-CENLEPGYRCICDPGY 228
P C +G C++L ++C+CD +
Sbjct: 1304 DP--CVNGGLCQDLLNKFQCLCDVAF 1327
Score = 65.7 bits (153), Expect = 3e-10
Identities = 51/200 (25%), Positives = 83/200 (41%), Gaps = 24/200 (12%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C ++ C ++ GG C + S+ C C G+ + + +++DEC C +G C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNPCIHGNCS 1192
Query: 137 NTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSC------QACPAQGSELYAVLCPE 187
+ ++ C C PG+T N D C + G +C +C G+ C +
Sbjct: 1193 DRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGN-FTGKFCRQ 1251
Query: 188 G--PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
PS G N T G G+C + +C+C PG+ + +DIDEC
Sbjct: 1252 SRLPSTVCGNEKTN-LTCYNG----GNCTEFQTELKCMCRPGF--TGEWCEKDIDEC-AS 1303
Query: 246 QSYCAGGQCRNTAGSFTCVC 265
GG C++ F C+C
Sbjct: 1304 DPCVNGGLCQDLLNKFQCLC 1323
Score = 61.3 bits (142), Expect = 7e-09
Identities = 52/172 (30%), Positives = 70/172 (40%), Gaps = 37/172 (21%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCR-RGRC------------ 54
N C++ + C C PGY GA C D++EC NP C+ G C
Sbjct: 313 NATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSNP--CQSNGECVELSSEKQYGRI 366
Query: 55 --------RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCE 106
+ A Y C+C+PGF T DV+EC+++ GG C N G++ C C
Sbjct: 367 TGLPSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424
Query: 107 AGYRPTATRGA--CVDV-DECEEQRVCRNGRC--HNTPG--SFRCECLPGFT 151
G C D+ C Q+ NG C H G F C C G+T
Sbjct: 425 FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
Score = 53.6 bits (123), Expect = 1e-06
Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 16/112 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDV----DEC---RDNPRVCRRGRCRNTA 58
C NG C + G+ C+C + G CR C + N G C
Sbjct: 1223 CANGATCISHTNGYSCLCFGNFT----GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQ 1278
Query: 59 GSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGY 109
C+C PGF +C D+DECA+D GG C + FQC+C+ +
Sbjct: 1279 TELKCMCRPGFT---GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 45.6 bits (103), Expect = 4e-04
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 7/66 (10%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C +C+C+PG+ G C +D+DEC +P V G C++ + CL
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGF----TGEWCEKDIDECASDPCV-NGGLCQDLLNKFQCL 1322
Query: 65 CEPGFA 70
C+ FA
Sbjct: 1323 CDVAFA 1328
Score = 42.3 bits (95), Expect = 0.003
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 12/94 (12%)
Query: 194 GGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGG 252
G +N C + P C HG +CE++ Y C C G+ L +IDEC + C G
Sbjct: 1136 GCLQLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGWSGKHCEL--NIDEC--FSNPCIHG 1189
Query: 253 QCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECE 285
C + ++ C C G T E+ DID C+
Sbjct: 1190 NCSDRVAAYHCTCEPGYTGVNCEV----DIDNCQ 1219
Score = 35.1 bits (77), Expect = 0.51
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G C ++DEC S G TC + G+Y CDC PG D
Sbjct: 218 GVNCELEIDEC-WSQPCLNGATCQDALGAYFCDCAPGFLGD 257
Score = 31.5 bits (68), Expect = 6.3
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 115 RGACVDVDECEEQRVCRNGRCHNTPGSFRCEC 146
+ CV D CE Q GRC N S++C+C
Sbjct: 667 KAGCVRKDWCESQPCQSRGRCINLWLSYQCDC 698
Score = 31.1 bits (67), Expect = 8.4
Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 409 CRDVDECALSAELCAGGTCVNTDG--SYRCDCPPG 441
C ++ + S TCVNT G S+ C CPPG
Sbjct: 67 CDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
>AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 96.3 bits (229), Expect = 2e-19
Identities = 99/376 (26%), Positives = 148/376 (39%), Gaps = 58/376 (15%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
GIC CIC GY G C D DEC +P C+ G C++ Y+C C P
Sbjct: 123 GICHQDPIYPVCICPAGYA----GRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVP 176
Query: 68 GFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G+ +C +VDECA+D C+N G + C+C Y +++DEC
Sbjct: 177 GYQ---GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE---LEIDECWS 230
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCP 186
Q C + G++ C+C PGF G C ++ C +Q L+ LC
Sbjct: 231 QPCLNGATCQDALGAYFCDCAPGFL----GDHC-------ELNTDECASQPC-LHGGLCV 278
Query: 187 EGPSK-----DNGGADINECTAVPGAC------PHGSCENLEPGYRCICDPGYHPDADGL 235
+G ++ G C + C + +CE+ Y C C PGY
Sbjct: 279 DGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY---TGAQ 335
Query: 236 CR-DIDECDMHQSYCAGGQC-----RNTAGSFTCVCPEGTRHEPELQLCRDIDECEG--- 286
C D++EC+ + + G+C G T + + HE +C G
Sbjct: 336 CEIDLNECNSNPCQ-SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC 394
Query: 287 ETETHYIESD-YERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
E + + S+ + G P P DN +GG +C +L T Q+C
Sbjct: 395 EEDVNECSSNPCQNGGTCENLPGNYTCHCPFDN-LSRTFYGGRDCS---DILLGCTHQQC 450
Query: 346 LDNRRGSCWRRVVDGQ 361
L+N G+C DGQ
Sbjct: 451 LNN--GTCIPHFQDGQ 464
Score = 90.6 bits (215), Expect = 1e-17
Identities = 85/285 (29%), Positives = 122/285 (42%), Gaps = 36/285 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDV-DECRDNPRVCR-RGRCRNTAG--SYTCL 64
N CK+ +C C + + C ++ D C NP C+ C NT G S+ C
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKD--CDNMKDPCFSNP--CQGSATCVNTPGERSFLCK 97
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C PG++ T + C +S GG C C+C AGY A R +D DEC
Sbjct: 98 CPPGYSGTICE--TTIGSCGKNSCQHGGICHQDPIYPVCICPAGY---AGRFCEIDHDEC 152
Query: 125 EEQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--- 180
C+NG C + + C C+PG+ GR C L++ S C + + L
Sbjct: 153 ASS-PCQNGAVCQDGIDGYSCFCVPGY----QGRHC-DLEVDECAS-DPCKNEATCLNEI 205
Query: 181 --YAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCR 237
Y +CP S N +I+EC + P C +G +C++ Y C C PG+ D L
Sbjct: 206 GRYTCICPHNYSGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCEL-- 261
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCP----EGTRHEPELQLC 278
+ DEC Q GG C + ++C C GT E + LC
Sbjct: 262 NTDEC-ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC 305
Score = 81.4 bits (192), Expect = 6e-15
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C +G C++I + C C G+ SG L ++DEC NP C G C + +Y
Sbjct: 1144 NSNPCLHGGNCEDIYSSYHCSCPLGW-SGKHCEL--NIDECFSNP--CIHGNCSDRVAAY 1198
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C CEPG+ T D+D C + G C++ + C+C + R + +
Sbjct: 1199 HCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 122 DECEEQR---VCRN-GRCHNTPGSFRCECLPGFT 151
C ++ C N G C +C C PGFT
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Score = 79.0 bits (186), Expect = 3e-14
Identities = 102/364 (28%), Positives = 137/364 (37%), Gaps = 57/364 (15%)
Query: 122 DECEEQRVCRNGRCHNTPG--SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGS 178
D C + C NTPG SF C+C PG++ T +G G SCQ
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFLCKCPPGYS-GTICETTIG-SCGKN-SCQHGGICHQD 128
Query: 179 ELYAV-LCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLC 236
+Y V +CP G + D +EC + P C +G+ C++ GY C C PGY L
Sbjct: 129 PIYPVCICPAGYAGRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDL- 185
Query: 237 RDIDECDMHQSYCAG-GQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHY 292
++DEC C C N G +TC+CP G E E+ C G T
Sbjct: 186 -EVDECASDP--CKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDA 242
Query: 293 IES---DYERGDIPPTFPTRT-ELAS-PC-DNGRCINTHGGFECECE-LGYV-------- 337
+ + D G + T E AS PC G C++ + C C G+
Sbjct: 243 LGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLM 302
Query: 338 ---------LDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-----ECC-CSVGLA 382
+AT + +DN CW QCE E EC S
Sbjct: 303 PLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 362
Query: 383 WGSXXXXXXXXXXXXXKGFAKL-----DGATCR-DVDECALSAELCA-GGTCVNTDGSYR 435
+G G+ + G C DV+EC S+ C GGTC N G+Y
Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNEC--SSNPCQNGGTCENLPGNYT 420
Query: 436 CDCP 439
C CP
Sbjct: 421 CHCP 424
Score = 70.1 bits (164), Expect = 1e-11
Identities = 54/206 (26%), Positives = 89/206 (43%), Gaps = 28/206 (13%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRC 94
C ++ C NP + G C + SY C C G++ +C ++DEC ++ C G C
Sbjct: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWS---GKHCELNIDECFSNP-CIHGNC 1191
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN 154
+ ++ C CE GY VD+D C+ + C + + C C FT
Sbjct: 1192 SDRVAAYHCTCEPGYTGVNCE---VDIDNCQSHQCANGATCISHTNGYSCLCFGNFT--- 1245
Query: 155 DGRTCLGLKLGWGV--------SCQA---CPAQGSELYAVLCPEGPSKDNGGADINECTA 203
G+ C +L V +C C +EL +C G + + DI+EC +
Sbjct: 1246 -GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGEWCEKDIDECAS 1303
Query: 204 VPGACPHGS-CENLEPGYRCICDPGY 228
P C +G C++L ++C+CD +
Sbjct: 1304 DP--CVNGGLCQDLLNKFQCLCDVAF 1327
Score = 65.7 bits (153), Expect = 3e-10
Identities = 51/200 (25%), Positives = 83/200 (41%), Gaps = 24/200 (12%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C ++ C ++ GG C + S+ C C G+ + + +++DEC C +G C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNPCIHGNCS 1192
Query: 137 NTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSC------QACPAQGSELYAVLCPE 187
+ ++ C C PG+T N D C + G +C +C G+ C +
Sbjct: 1193 DRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGN-FTGKFCRQ 1251
Query: 188 G--PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
PS G N T G G+C + +C+C PG+ + +DIDEC
Sbjct: 1252 SRLPSTVCGNEKTN-LTCYNG----GNCTEFQTELKCMCRPGF--TGEWCEKDIDEC-AS 1303
Query: 246 QSYCAGGQCRNTAGSFTCVC 265
GG C++ F C+C
Sbjct: 1304 DPCVNGGLCQDLLNKFQCLC 1323
Score = 61.3 bits (142), Expect = 7e-09
Identities = 52/172 (30%), Positives = 70/172 (40%), Gaps = 37/172 (21%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCR-RGRC------------ 54
N C++ + C C PGY GA C D++EC NP C+ G C
Sbjct: 313 NATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSNP--CQSNGECVELSSEKQYGRI 366
Query: 55 --------RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCE 106
+ A Y C+C+PGF T DV+EC+++ GG C N G++ C C
Sbjct: 367 TGLPSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424
Query: 107 AGYRPTATRGA--CVDV-DECEEQRVCRNGRC--HNTPG--SFRCECLPGFT 151
G C D+ C Q+ NG C H G F C C G+T
Sbjct: 425 FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
Score = 53.6 bits (123), Expect = 1e-06
Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 16/112 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDV----DEC---RDNPRVCRRGRCRNTA 58
C NG C + G+ C+C + G CR C + N G C
Sbjct: 1223 CANGATCISHTNGYSCLCFGNFT----GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQ 1278
Query: 59 GSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGY 109
C+C PGF +C D+DECA+D GG C + FQC+C+ +
Sbjct: 1279 TELKCMCRPGFT---GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 45.6 bits (103), Expect = 4e-04
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 7/66 (10%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C +C+C+PG+ G C +D+DEC +P V G C++ + CL
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGF----TGEWCEKDIDECASDPCV-NGGLCQDLLNKFQCL 1322
Query: 65 CEPGFA 70
C+ FA
Sbjct: 1323 CDVAFA 1328
Score = 42.3 bits (95), Expect = 0.003
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 12/94 (12%)
Query: 194 GGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGG 252
G +N C + P C HG +CE++ Y C C G+ L +IDEC + C G
Sbjct: 1136 GCLQLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGWSGKHCEL--NIDEC--FSNPCIHG 1189
Query: 253 QCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECE 285
C + ++ C C G T E+ DID C+
Sbjct: 1190 NCSDRVAAYHCTCEPGYTGVNCEV----DIDNCQ 1219
Score = 35.1 bits (77), Expect = 0.51
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G C ++DEC S G TC + G+Y CDC PG D
Sbjct: 218 GVNCELEIDEC-WSQPCLNGATCQDALGAYFCDCAPGFLGD 257
Score = 31.5 bits (68), Expect = 6.3
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 115 RGACVDVDECEEQRVCRNGRCHNTPGSFRCEC 146
+ CV D CE Q GRC N S++C+C
Sbjct: 667 KAGCVRKDWCESQPCQSRGRCINLWLSYQCDC 698
Score = 31.1 bits (67), Expect = 8.4
Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 409 CRDVDECALSAELCAGGTCVNTDG--SYRCDCPPG 441
C ++ + S TCVNT G S+ C CPPG
Sbjct: 67 CDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
>AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 96.3 bits (229), Expect = 2e-19
Identities = 99/376 (26%), Positives = 148/376 (39%), Gaps = 58/376 (15%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
GIC CIC GY G C D DEC +P C+ G C++ Y+C C P
Sbjct: 123 GICHQDPIYPVCICPAGYA----GRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVP 176
Query: 68 GFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G+ +C +VDECA+D C+N G + C+C Y +++DEC
Sbjct: 177 GYQ---GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE---LEIDECWS 230
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCP 186
Q C + G++ C+C PGF G C ++ C +Q L+ LC
Sbjct: 231 QPCLNGATCQDALGAYFCDCAPGFL----GDHC-------ELNTDECASQPC-LHGGLCV 278
Query: 187 EGPSK-----DNGGADINECTAVPGAC------PHGSCENLEPGYRCICDPGYHPDADGL 235
+G ++ G C + C + +CE+ Y C C PGY
Sbjct: 279 DGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY---TGAQ 335
Query: 236 CR-DIDECDMHQSYCAGGQC-----RNTAGSFTCVCPEGTRHEPELQLCRDIDECEG--- 286
C D++EC+ + + G+C G T + + HE +C G
Sbjct: 336 CEIDLNECNSNPCQ-SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC 394
Query: 287 ETETHYIESD-YERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
E + + S+ + G P P DN +GG +C +L T Q+C
Sbjct: 395 EEDVNECSSNPCQNGGTCENLPGNYTCHCPFDN-LSRTFYGGRDCS---DILLGCTHQQC 450
Query: 346 LDNRRGSCWRRVVDGQ 361
L+N G+C DGQ
Sbjct: 451 LNN--GTCIPHFQDGQ 464
Score = 90.6 bits (215), Expect = 1e-17
Identities = 85/285 (29%), Positives = 122/285 (42%), Gaps = 36/285 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDV-DECRDNPRVCR-RGRCRNTAG--SYTCL 64
N CK+ +C C + + C ++ D C NP C+ C NT G S+ C
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKD--CDNMKDPCFSNP--CQGSATCVNTPGERSFLCK 97
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C PG++ T + C +S GG C C+C AGY A R +D DEC
Sbjct: 98 CPPGYSGTICE--TTIGSCGKNSCQHGGICHQDPIYPVCICPAGY---AGRFCEIDHDEC 152
Query: 125 EEQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--- 180
C+NG C + + C C+PG+ GR C L++ S C + + L
Sbjct: 153 ASS-PCQNGAVCQDGIDGYSCFCVPGY----QGRHC-DLEVDECAS-DPCKNEATCLNEI 205
Query: 181 --YAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCR 237
Y +CP S N +I+EC + P C +G +C++ Y C C PG+ D L
Sbjct: 206 GRYTCICPHNYSGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCEL-- 261
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCP----EGTRHEPELQLC 278
+ DEC Q GG C + ++C C GT E + LC
Sbjct: 262 NTDEC-ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC 305
Score = 81.4 bits (192), Expect = 6e-15
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C +G C++I + C C G+ SG L ++DEC NP C G C + +Y
Sbjct: 1144 NSNPCLHGGNCEDIYSSYHCSCPLGW-SGKHCEL--NIDECFSNP--CIHGNCSDRVAAY 1198
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C CEPG+ T D+D C + G C++ + C+C + R + +
Sbjct: 1199 HCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 122 DECEEQR---VCRN-GRCHNTPGSFRCECLPGFT 151
C ++ C N G C +C C PGFT
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Score = 79.0 bits (186), Expect = 3e-14
Identities = 102/364 (28%), Positives = 137/364 (37%), Gaps = 57/364 (15%)
Query: 122 DECEEQRVCRNGRCHNTPG--SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGS 178
D C + C NTPG SF C+C PG++ T +G G SCQ
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFLCKCPPGYS-GTICETTIG-SCGKN-SCQHGGICHQD 128
Query: 179 ELYAV-LCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLC 236
+Y V +CP G + D +EC + P C +G+ C++ GY C C PGY L
Sbjct: 129 PIYPVCICPAGYAGRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDL- 185
Query: 237 RDIDECDMHQSYCAG-GQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHY 292
++DEC C C N G +TC+CP G E E+ C G T
Sbjct: 186 -EVDECASDP--CKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDA 242
Query: 293 IES---DYERGDIPPTFPTRT-ELAS-PC-DNGRCINTHGGFECECE-LGYV-------- 337
+ + D G + T E AS PC G C++ + C C G+
Sbjct: 243 LGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLM 302
Query: 338 ---------LDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-----ECC-CSVGLA 382
+AT + +DN CW QCE E EC S
Sbjct: 303 PLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 362
Query: 383 WGSXXXXXXXXXXXXXKGFAKL-----DGATCR-DVDECALSAELCA-GGTCVNTDGSYR 435
+G G+ + G C DV+EC S+ C GGTC N G+Y
Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNEC--SSNPCQNGGTCENLPGNYT 420
Query: 436 CDCP 439
C CP
Sbjct: 421 CHCP 424
Score = 70.1 bits (164), Expect = 1e-11
Identities = 54/206 (26%), Positives = 89/206 (43%), Gaps = 28/206 (13%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRC 94
C ++ C NP + G C + SY C C G++ +C ++DEC ++ C G C
Sbjct: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWS---GKHCELNIDECFSNP-CIHGNC 1191
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN 154
+ ++ C CE GY VD+D C+ + C + + C C FT
Sbjct: 1192 SDRVAAYHCTCEPGYTGVNCE---VDIDNCQSHQCANGATCISHTNGYSCLCFGNFT--- 1245
Query: 155 DGRTCLGLKLGWGV--------SCQA---CPAQGSELYAVLCPEGPSKDNGGADINECTA 203
G+ C +L V +C C +EL +C G + + DI+EC +
Sbjct: 1246 -GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGEWCEKDIDECAS 1303
Query: 204 VPGACPHGS-CENLEPGYRCICDPGY 228
P C +G C++L ++C+CD +
Sbjct: 1304 DP--CVNGGLCQDLLNKFQCLCDVAF 1327
Score = 65.7 bits (153), Expect = 3e-10
Identities = 51/200 (25%), Positives = 83/200 (41%), Gaps = 24/200 (12%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C ++ C ++ GG C + S+ C C G+ + + +++DEC C +G C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNPCIHGNCS 1192
Query: 137 NTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSC------QACPAQGSELYAVLCPE 187
+ ++ C C PG+T N D C + G +C +C G+ C +
Sbjct: 1193 DRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGN-FTGKFCRQ 1251
Query: 188 G--PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
PS G N T G G+C + +C+C PG+ + +DIDEC
Sbjct: 1252 SRLPSTVCGNEKTN-LTCYNG----GNCTEFQTELKCMCRPGF--TGEWCEKDIDEC-AS 1303
Query: 246 QSYCAGGQCRNTAGSFTCVC 265
GG C++ F C+C
Sbjct: 1304 DPCVNGGLCQDLLNKFQCLC 1323
Score = 61.3 bits (142), Expect = 7e-09
Identities = 52/172 (30%), Positives = 70/172 (40%), Gaps = 37/172 (21%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCR-RGRC------------ 54
N C++ + C C PGY GA C D++EC NP C+ G C
Sbjct: 313 NATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSNP--CQSNGECVELSSEKQYGRI 366
Query: 55 --------RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCE 106
+ A Y C+C+PGF T DV+EC+++ GG C N G++ C C
Sbjct: 367 TGLPSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424
Query: 107 AGYRPTATRGA--CVDV-DECEEQRVCRNGRC--HNTPG--SFRCECLPGFT 151
G C D+ C Q+ NG C H G F C C G+T
Sbjct: 425 FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
Score = 53.6 bits (123), Expect = 1e-06
Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 16/112 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDV----DEC---RDNPRVCRRGRCRNTA 58
C NG C + G+ C+C + G CR C + N G C
Sbjct: 1223 CANGATCISHTNGYSCLCFGNFT----GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQ 1278
Query: 59 GSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGY 109
C+C PGF +C D+DECA+D GG C + FQC+C+ +
Sbjct: 1279 TELKCMCRPGFT---GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 45.6 bits (103), Expect = 4e-04
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 7/66 (10%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C +C+C+PG+ G C +D+DEC +P V G C++ + CL
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGF----TGEWCEKDIDECASDPCV-NGGLCQDLLNKFQCL 1322
Query: 65 CEPGFA 70
C+ FA
Sbjct: 1323 CDVAFA 1328
Score = 42.3 bits (95), Expect = 0.003
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 12/94 (12%)
Query: 194 GGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGG 252
G +N C + P C HG +CE++ Y C C G+ L +IDEC + C G
Sbjct: 1136 GCLQLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGWSGKHCEL--NIDEC--FSNPCIHG 1189
Query: 253 QCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECE 285
C + ++ C C G T E+ DID C+
Sbjct: 1190 NCSDRVAAYHCTCEPGYTGVNCEV----DIDNCQ 1219
Score = 35.1 bits (77), Expect = 0.51
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G C ++DEC S G TC + G+Y CDC PG D
Sbjct: 218 GVNCELEIDEC-WSQPCLNGATCQDALGAYFCDCAPGFLGD 257
Score = 31.5 bits (68), Expect = 6.3
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 115 RGACVDVDECEEQRVCRNGRCHNTPGSFRCEC 146
+ CV D CE Q GRC N S++C+C
Sbjct: 667 KAGCVRKDWCESQPCQSRGRCINLWLSYQCDC 698
Score = 31.1 bits (67), Expect = 8.4
Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 409 CRDVDECALSAELCAGGTCVNTDG--SYRCDCPPG 441
C ++ + S TCVNT G S+ C CPPG
Sbjct: 67 CDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
>AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 96.3 bits (229), Expect = 2e-19
Identities = 99/376 (26%), Positives = 148/376 (39%), Gaps = 58/376 (15%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
GIC CIC GY G C D DEC +P C+ G C++ Y+C C P
Sbjct: 123 GICHQDPIYPVCICPAGYA----GRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVP 176
Query: 68 GFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G+ +C +VDECA+D C+N G + C+C Y +++DEC
Sbjct: 177 GYQ---GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE---LEIDECWS 230
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCP 186
Q C + G++ C+C PGF G C ++ C +Q L+ LC
Sbjct: 231 QPCLNGATCQDALGAYFCDCAPGFL----GDHC-------ELNTDECASQPC-LHGGLCV 278
Query: 187 EGPSK-----DNGGADINECTAVPGAC------PHGSCENLEPGYRCICDPGYHPDADGL 235
+G ++ G C + C + +CE+ Y C C PGY
Sbjct: 279 DGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY---TGAQ 335
Query: 236 CR-DIDECDMHQSYCAGGQC-----RNTAGSFTCVCPEGTRHEPELQLCRDIDECEG--- 286
C D++EC+ + + G+C G T + + HE +C G
Sbjct: 336 CEIDLNECNSNPCQ-SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC 394
Query: 287 ETETHYIESD-YERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
E + + S+ + G P P DN +GG +C +L T Q+C
Sbjct: 395 EEDVNECSSNPCQNGGTCENLPGNYTCHCPFDN-LSRTFYGGRDCS---DILLGCTHQQC 450
Query: 346 LDNRRGSCWRRVVDGQ 361
L+N G+C DGQ
Sbjct: 451 LNN--GTCIPHFQDGQ 464
Score = 90.6 bits (215), Expect = 1e-17
Identities = 85/285 (29%), Positives = 122/285 (42%), Gaps = 36/285 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDV-DECRDNPRVCR-RGRCRNTAG--SYTCL 64
N CK+ +C C + + C ++ D C NP C+ C NT G S+ C
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKD--CDNMKDPCFSNP--CQGSATCVNTPGERSFLCK 97
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C PG++ T + C +S GG C C+C AGY A R +D DEC
Sbjct: 98 CPPGYSGTICE--TTIGSCGKNSCQHGGICHQDPIYPVCICPAGY---AGRFCEIDHDEC 152
Query: 125 EEQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--- 180
C+NG C + + C C+PG+ GR C L++ S C + + L
Sbjct: 153 ASS-PCQNGAVCQDGIDGYSCFCVPGY----QGRHC-DLEVDECAS-DPCKNEATCLNEI 205
Query: 181 --YAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCR 237
Y +CP S N +I+EC + P C +G +C++ Y C C PG+ D L
Sbjct: 206 GRYTCICPHNYSGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCEL-- 261
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCP----EGTRHEPELQLC 278
+ DEC Q GG C + ++C C GT E + LC
Sbjct: 262 NTDEC-ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC 305
Score = 81.4 bits (192), Expect = 6e-15
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C +G C++I + C C G+ SG L ++DEC NP C G C + +Y
Sbjct: 1144 NSNPCLHGGNCEDIYSSYHCSCPLGW-SGKHCEL--NIDECFSNP--CIHGNCSDRVAAY 1198
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C CEPG+ T D+D C + G C++ + C+C + R + +
Sbjct: 1199 HCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 122 DECEEQR---VCRN-GRCHNTPGSFRCECLPGFT 151
C ++ C N G C +C C PGFT
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Score = 79.0 bits (186), Expect = 3e-14
Identities = 102/364 (28%), Positives = 137/364 (37%), Gaps = 57/364 (15%)
Query: 122 DECEEQRVCRNGRCHNTPG--SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGS 178
D C + C NTPG SF C+C PG++ T +G G SCQ
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFLCKCPPGYS-GTICETTIG-SCGKN-SCQHGGICHQD 128
Query: 179 ELYAV-LCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLC 236
+Y V +CP G + D +EC + P C +G+ C++ GY C C PGY L
Sbjct: 129 PIYPVCICPAGYAGRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDL- 185
Query: 237 RDIDECDMHQSYCAG-GQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHY 292
++DEC C C N G +TC+CP G E E+ C G T
Sbjct: 186 -EVDECASDP--CKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDA 242
Query: 293 IES---DYERGDIPPTFPTRT-ELAS-PC-DNGRCINTHGGFECECE-LGYV-------- 337
+ + D G + T E AS PC G C++ + C C G+
Sbjct: 243 LGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLM 302
Query: 338 ---------LDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-----ECC-CSVGLA 382
+AT + +DN CW QCE E EC S
Sbjct: 303 PLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 362
Query: 383 WGSXXXXXXXXXXXXXKGFAKL-----DGATCR-DVDECALSAELCA-GGTCVNTDGSYR 435
+G G+ + G C DV+EC S+ C GGTC N G+Y
Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNEC--SSNPCQNGGTCENLPGNYT 420
Query: 436 CDCP 439
C CP
Sbjct: 421 CHCP 424
Score = 70.1 bits (164), Expect = 1e-11
Identities = 54/206 (26%), Positives = 89/206 (43%), Gaps = 28/206 (13%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRC 94
C ++ C NP + G C + SY C C G++ +C ++DEC ++ C G C
Sbjct: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWS---GKHCELNIDECFSNP-CIHGNC 1191
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN 154
+ ++ C CE GY VD+D C+ + C + + C C FT
Sbjct: 1192 SDRVAAYHCTCEPGYTGVNCE---VDIDNCQSHQCANGATCISHTNGYSCLCFGNFT--- 1245
Query: 155 DGRTCLGLKLGWGV--------SCQA---CPAQGSELYAVLCPEGPSKDNGGADINECTA 203
G+ C +L V +C C +EL +C G + + DI+EC +
Sbjct: 1246 -GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGEWCEKDIDECAS 1303
Query: 204 VPGACPHGS-CENLEPGYRCICDPGY 228
P C +G C++L ++C+CD +
Sbjct: 1304 DP--CVNGGLCQDLLNKFQCLCDVAF 1327
Score = 65.7 bits (153), Expect = 3e-10
Identities = 51/200 (25%), Positives = 83/200 (41%), Gaps = 24/200 (12%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C ++ C ++ GG C + S+ C C G+ + + +++DEC C +G C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNPCIHGNCS 1192
Query: 137 NTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSC------QACPAQGSELYAVLCPE 187
+ ++ C C PG+T N D C + G +C +C G+ C +
Sbjct: 1193 DRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGN-FTGKFCRQ 1251
Query: 188 G--PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
PS G N T G G+C + +C+C PG+ + +DIDEC
Sbjct: 1252 SRLPSTVCGNEKTN-LTCYNG----GNCTEFQTELKCMCRPGF--TGEWCEKDIDEC-AS 1303
Query: 246 QSYCAGGQCRNTAGSFTCVC 265
GG C++ F C+C
Sbjct: 1304 DPCVNGGLCQDLLNKFQCLC 1323
Score = 61.3 bits (142), Expect = 7e-09
Identities = 52/172 (30%), Positives = 70/172 (40%), Gaps = 37/172 (21%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCR-RGRC------------ 54
N C++ + C C PGY GA C D++EC NP C+ G C
Sbjct: 313 NATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSNP--CQSNGECVELSSEKQYGRI 366
Query: 55 --------RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCE 106
+ A Y C+C+PGF T DV+EC+++ GG C N G++ C C
Sbjct: 367 TGLPSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424
Query: 107 AGYRPTATRGA--CVDV-DECEEQRVCRNGRC--HNTPG--SFRCECLPGFT 151
G C D+ C Q+ NG C H G F C C G+T
Sbjct: 425 FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
Score = 53.6 bits (123), Expect = 1e-06
Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 16/112 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDV----DEC---RDNPRVCRRGRCRNTA 58
C NG C + G+ C+C + G CR C + N G C
Sbjct: 1223 CANGATCISHTNGYSCLCFGNFT----GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQ 1278
Query: 59 GSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGY 109
C+C PGF +C D+DECA+D GG C + FQC+C+ +
Sbjct: 1279 TELKCMCRPGFT---GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 45.6 bits (103), Expect = 4e-04
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 7/66 (10%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C +C+C+PG+ G C +D+DEC +P V G C++ + CL
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGF----TGEWCEKDIDECASDPCV-NGGLCQDLLNKFQCL 1322
Query: 65 CEPGFA 70
C+ FA
Sbjct: 1323 CDVAFA 1328
Score = 42.3 bits (95), Expect = 0.003
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 12/94 (12%)
Query: 194 GGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGG 252
G +N C + P C HG +CE++ Y C C G+ L +IDEC + C G
Sbjct: 1136 GCLQLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGWSGKHCEL--NIDEC--FSNPCIHG 1189
Query: 253 QCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECE 285
C + ++ C C G T E+ DID C+
Sbjct: 1190 NCSDRVAAYHCTCEPGYTGVNCEV----DIDNCQ 1219
Score = 35.1 bits (77), Expect = 0.51
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G C ++DEC S G TC + G+Y CDC PG D
Sbjct: 218 GVNCELEIDEC-WSQPCLNGATCQDALGAYFCDCAPGFLGD 257
Score = 31.5 bits (68), Expect = 6.3
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 115 RGACVDVDECEEQRVCRNGRCHNTPGSFRCEC 146
+ CV D CE Q GRC N S++C+C
Sbjct: 667 KAGCVRKDWCESQPCQSRGRCINLWLSYQCDC 698
Score = 31.1 bits (67), Expect = 8.4
Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 409 CRDVDECALSAELCAGGTCVNTDG--SYRCDCPPG 441
C ++ + S TCVNT G S+ C CPPG
Sbjct: 67 CDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
>AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.
Length = 1376
Score = 96.3 bits (229), Expect = 2e-19
Identities = 99/376 (26%), Positives = 148/376 (39%), Gaps = 58/376 (15%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCRRGR-CRNTAGSYTCLCEP 67
GIC CIC GY G C D DEC +P C+ G C++ Y+C C P
Sbjct: 123 GICHQDPIYPVCICPAGYA----GRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVP 176
Query: 68 GFAPTAAGYC-ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE 126
G+ +C +VDECA+D C+N G + C+C Y +++DEC
Sbjct: 177 GYQ---GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE---LEIDECWS 230
Query: 127 QRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYAVLCP 186
Q C + G++ C+C PGF G C ++ C +Q L+ LC
Sbjct: 231 QPCLNGATCQDALGAYFCDCAPGFL----GDHC-------ELNTDECASQPC-LHGGLCV 278
Query: 187 EGPSK-----DNGGADINECTAVPGAC------PHGSCENLEPGYRCICDPGYHPDADGL 235
+G ++ G C + C + +CE+ Y C C PGY
Sbjct: 279 DGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY---TGAQ 335
Query: 236 CR-DIDECDMHQSYCAGGQC-----RNTAGSFTCVCPEGTRHEPELQLCRDIDECEG--- 286
C D++EC+ + + G+C G T + + HE +C G
Sbjct: 336 CEIDLNECNSNPCQ-SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC 394
Query: 287 ETETHYIESD-YERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYVLDATAQRC 345
E + + S+ + G P P DN +GG +C +L T Q+C
Sbjct: 395 EEDVNECSSNPCQNGGTCENLPGNYTCHCPFDN-LSRTFYGGRDCS---DILLGCTHQQC 450
Query: 346 LDNRRGSCWRRVVDGQ 361
L+N G+C DGQ
Sbjct: 451 LNN--GTCIPHFQDGQ 464
Score = 90.6 bits (215), Expect = 1e-17
Identities = 85/285 (29%), Positives = 122/285 (42%), Gaps = 36/285 (12%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDV-DECRDNPRVCR-RGRCRNTAG--SYTCL 64
N CK+ +C C + + C ++ D C NP C+ C NT G S+ C
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKD--CDNMKDPCFSNP--CQGSATCVNTPGERSFLCK 97
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C PG++ T + C +S GG C C+C AGY A R +D DEC
Sbjct: 98 CPPGYSGTICE--TTIGSCGKNSCQHGGICHQDPIYPVCICPAGY---AGRFCEIDHDEC 152
Query: 125 EEQRVCRNGR-CHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSEL--- 180
C+NG C + + C C+PG+ GR C L++ S C + + L
Sbjct: 153 ASS-PCQNGAVCQDGIDGYSCFCVPGY----QGRHC-DLEVDECAS-DPCKNEATCLNEI 205
Query: 181 --YAVLCPEGPSKDNGGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCR 237
Y +CP S N +I+EC + P C +G +C++ Y C C PG+ D L
Sbjct: 206 GRYTCICPHNYSGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCEL-- 261
Query: 238 DIDECDMHQSYCAGGQCRNTAGSFTCVCP----EGTRHEPELQLC 278
+ DEC Q GG C + ++C C GT E + LC
Sbjct: 262 NTDEC-ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC 305
Score = 81.4 bits (192), Expect = 6e-15
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 3 NGGMCTNG-ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSY 61
N C +G C++I + C C G+ SG L ++DEC NP C G C + +Y
Sbjct: 1144 NSNPCLHGGNCEDIYSSYHCSCPLGW-SGKHCEL--NIDECFSNP--CIHGNCSDRVAAY 1198
Query: 62 TCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDV 121
C CEPG+ T D+D C + G C++ + C+C + R + +
Sbjct: 1199 HCTCEPGY--TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 122 DECEEQR---VCRN-GRCHNTPGSFRCECLPGFT 151
C ++ C N G C +C C PGFT
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT 1290
Score = 79.0 bits (186), Expect = 3e-14
Identities = 102/364 (28%), Positives = 137/364 (37%), Gaps = 57/364 (15%)
Query: 122 DECEEQRVCRNGRCHNTPG--SFRCECLPGFTLSNDGRTCLGLKLGWGVSCQ-ACPAQGS 178
D C + C NTPG SF C+C PG++ T +G G SCQ
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFLCKCPPGYS-GTICETTIG-SCGKN-SCQHGGICHQD 128
Query: 179 ELYAV-LCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPDADGLC 236
+Y V +CP G + D +EC + P C +G+ C++ GY C C PGY L
Sbjct: 129 PIYPVCICPAGYAGRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDL- 185
Query: 237 RDIDECDMHQSYCAG-GQCRNTAGSFTCVCPE---GTRHEPELQLCRDIDECEGETETHY 292
++DEC C C N G +TC+CP G E E+ C G T
Sbjct: 186 -EVDECASDP--CKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDA 242
Query: 293 IES---DYERGDIPPTFPTRT-ELAS-PC-DNGRCINTHGGFECECE-LGYV-------- 337
+ + D G + T E AS PC G C++ + C C G+
Sbjct: 243 LGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLM 302
Query: 338 ---------LDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQ-----ECC-CSVGLA 382
+AT + +DN CW QCE E EC S
Sbjct: 303 PLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 362
Query: 383 WGSXXXXXXXXXXXXXKGFAKL-----DGATCR-DVDECALSAELCA-GGTCVNTDGSYR 435
+G G+ + G C DV+EC S+ C GGTC N G+Y
Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNEC--SSNPCQNGGTCENLPGNYT 420
Query: 436 CDCP 439
C CP
Sbjct: 421 CHCP 424
Score = 70.1 bits (164), Expect = 1e-11
Identities = 54/206 (26%), Positives = 89/206 (43%), Gaps = 28/206 (13%)
Query: 36 CRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRC 94
C ++ C NP + G C + SY C C G++ +C ++DEC ++ C G C
Sbjct: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWS---GKHCELNIDECFSNP-CIHGNC 1191
Query: 95 VNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSN 154
+ ++ C CE GY VD+D C+ + C + + C C FT
Sbjct: 1192 SDRVAAYHCTCEPGYTGVNCE---VDIDNCQSHQCANGATCISHTNGYSCLCFGNFT--- 1245
Query: 155 DGRTCLGLKLGWGV--------SCQA---CPAQGSELYAVLCPEGPSKDNGGADINECTA 203
G+ C +L V +C C +EL +C G + + DI+EC +
Sbjct: 1246 -GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGEWCEKDIDECAS 1303
Query: 204 VPGACPHGS-CENLEPGYRCICDPGY 228
P C +G C++L ++C+CD +
Sbjct: 1304 DP--CVNGGLCQDLLNKFQCLCDVAF 1327
Score = 65.7 bits (153), Expect = 3e-10
Identities = 51/200 (25%), Positives = 83/200 (41%), Gaps = 24/200 (12%)
Query: 77 CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCH 136
C ++ C ++ GG C + S+ C C G+ + + +++DEC C +G C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGW---SGKHCELNIDEC-FSNPCIHGNCS 1192
Query: 137 NTPGSFRCECLPGFTLSN---DGRTCLGLKLGWGVSC------QACPAQGSELYAVLCPE 187
+ ++ C C PG+T N D C + G +C +C G+ C +
Sbjct: 1193 DRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGN-FTGKFCRQ 1251
Query: 188 G--PSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMH 245
PS G N T G G+C + +C+C PG+ + +DIDEC
Sbjct: 1252 SRLPSTVCGNEKTN-LTCYNG----GNCTEFQTELKCMCRPGF--TGEWCEKDIDEC-AS 1303
Query: 246 QSYCAGGQCRNTAGSFTCVC 265
GG C++ F C+C
Sbjct: 1304 DPCVNGGLCQDLLNKFQCLC 1323
Score = 61.3 bits (142), Expect = 7e-09
Identities = 52/172 (30%), Positives = 70/172 (40%), Gaps = 37/172 (21%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCR-DVDECRDNPRVCR-RGRC------------ 54
N C++ + C C PGY GA C D++EC NP C+ G C
Sbjct: 313 NATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSNP--CQSNGECVELSSEKQYGRI 366
Query: 55 --------RNTAGSYTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCE 106
+ A Y C+C+PGF T DV+EC+++ GG C N G++ C C
Sbjct: 367 TGLPSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424
Query: 107 AGYRPTATRGA--CVDV-DECEEQRVCRNGRC--HNTPG--SFRCECLPGFT 151
G C D+ C Q+ NG C H G F C C G+T
Sbjct: 425 FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
Score = 53.6 bits (123), Expect = 1e-06
Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 16/112 (14%)
Query: 7 CTNGI-CKNIDGGFECICKPGYESGSEGALCRDV----DEC---RDNPRVCRRGRCRNTA 58
C NG C + G+ C+C + G CR C + N G C
Sbjct: 1223 CANGATCISHTNGYSCLCFGNFT----GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQ 1278
Query: 59 GSYTCLCEPGFAPTAAGYCA-DVDECAADSMCKGGRCVNSEGSFQCVCEAGY 109
C+C PGF +C D+DECA+D GG C + FQC+C+ +
Sbjct: 1279 TELKCMCRPGFT---GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
Score = 45.6 bits (103), Expect = 4e-04
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 7/66 (10%)
Query: 7 CTNG-ICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCL 64
C NG C +C+C+PG+ G C +D+DEC +P V G C++ + CL
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGF----TGEWCEKDIDECASDPCV-NGGLCQDLLNKFQCL 1322
Query: 65 CEPGFA 70
C+ FA
Sbjct: 1323 CDVAFA 1328
Score = 42.3 bits (95), Expect = 0.003
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 12/94 (12%)
Query: 194 GGADINECTAVPGACPHG-SCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGG 252
G +N C + P C HG +CE++ Y C C G+ L +IDEC + C G
Sbjct: 1136 GCLQLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGWSGKHCEL--NIDEC--FSNPCIHG 1189
Query: 253 QCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECE 285
C + ++ C C G T E+ DID C+
Sbjct: 1190 NCSDRVAAYHCTCEPGYTGVNCEV----DIDNCQ 1219
Score = 35.1 bits (77), Expect = 0.51
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 406 GATCR-DVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLD 445
G C ++DEC S G TC + G+Y CDC PG D
Sbjct: 218 GVNCELEIDEC-WSQPCLNGATCQDALGAYFCDCAPGFLGD 257
Score = 31.5 bits (68), Expect = 6.3
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 115 RGACVDVDECEEQRVCRNGRCHNTPGSFRCEC 146
+ CV D CE Q GRC N S++C+C
Sbjct: 667 KAGCVRKDWCESQPCQSRGRCINLWLSYQCDC 698
Score = 31.1 bits (67), Expect = 8.4
Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 409 CRDVDECALSAELCAGGTCVNTDG--SYRCDCPPG 441
C ++ + S TCVNT G S+ C CPPG
Sbjct: 67 CDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
>X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein.
Length = 1246
Score = 94.3 bits (224), Expect = 8e-19
Identities = 56/169 (33%), Positives = 80/169 (47%), Gaps = 19/169 (11%)
Query: 5 GMCTNGICK-NIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G TN C+ F C C G+ +G C D+DEC + P VC C N G++
Sbjct: 677 GCDTNAACRPGPRTQFTCECSIGFRG--DGRTCYDIDECSEQPSVCGSHTICNNHPGTFR 734
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGG----------RCVNSEGS-FQCVCEAGYRP 111
C C G+ + G C V + + C+ G +C+ + GS + C C G+
Sbjct: 735 CECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF-- 792
Query: 112 TATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
+ AC DVDEC+ R + C+NTPGSF C+C PG+ DG C+
Sbjct: 793 SGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRCV 839
Score = 76.2 bits (179), Expect = 2e-13
Identities = 53/166 (31%), Positives = 73/166 (43%), Gaps = 26/166 (15%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ-RVCRNGR-CHNTPG 140
C ++ C+ G F C C G+R C D+DEC EQ VC + C+N PG
Sbjct: 678 CDTNAACRPG----PRTQFTCECSIGFRGDGR--TCYDIDECSEQPSVCGSHTICNNHPG 731
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQA------------CPAQGSELYAVLCPE 187
+FRCEC+ G+ S++G TC+ + ++ C+ C G Y C
Sbjct: 732 TFRCECVEGYQFSDEG-TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLP 790
Query: 188 GPSKDNGGA-DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPD 231
G S D D++EC P C P C N + C C PGY D
Sbjct: 791 GFSGDGQACQDVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGD 834
Score = 54.8 bits (126), Expect = 6e-07
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 13/100 (13%)
Query: 197 DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDADGLC------RDIDECDMHQSYC 249
DI+EC+ P C H C N +RC C GY +G C R I+ C+ C
Sbjct: 709 DIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNC 768
Query: 250 ---AGGQCRNTAG-SFTCVCPEGTRHEPELQLCRDIDECE 285
QC T G S+TC C G + Q C+D+DEC+
Sbjct: 769 DIPQRAQCIYTGGSSYTCSCLPG--FSGDGQACQDVDECQ 806
Score = 50.0 bits (114), Expect = 2e-05
Identities = 53/183 (28%), Positives = 65/183 (35%), Gaps = 41/183 (22%)
Query: 111 PTATRGAC-VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK------ 163
P A + C + C+ CR G F CEC GF DGRTC +
Sbjct: 664 PDALQNPCYIGTHGCDTNAACRPG----PRTQFTCECSIGFR--GDGRTCYDIDECSEQP 717
Query: 164 --LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCE----NLE 217
G C P + C EG + G C AV P CE N +
Sbjct: 718 SVCGSHTICNNHPGT----FRCECVEGYQFSDEGT----CVAVVDQRPINYCETGLHNCD 769
Query: 218 ------------PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
Y C C PG+ D C+D+DEC + + C NT GSFTC C
Sbjct: 770 IPQRAQCIYTGGSSYTCSCLPGFSGDGQA-CQDVDECQPSRCH-PDAFCYNTPGSFTCQC 827
Query: 266 PEG 268
G
Sbjct: 828 KPG 830
Score = 46.8 bits (106), Expect = 2e-04
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPGLTLDSTGT 449
DG TC D+DEC+ +C T C N G++RC+C G GT
Sbjct: 703 DGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGT 748
Score = 46.0 bits (104), Expect = 3e-04
Identities = 37/130 (28%), Positives = 50/130 (38%), Gaps = 20/130 (15%)
Query: 220 YRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLC 278
+ C C G+ D C DIDEC S C C N G+F C C EG + E
Sbjct: 692 FTCECSIGFRGDGR-TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCV 750
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYV 337
+D + +Y E+ DIP +CI T G + C C G+
Sbjct: 751 AVVD----QRPINYCETGLHNCDIP-------------QRAQCIYTGGSSYTCSCLPGFS 793
Query: 338 LDATAQRCLD 347
D A + +D
Sbjct: 794 GDGQACQDVD 803
Score = 43.2 bits (97), Expect = 0.002
Identities = 43/145 (29%), Positives = 52/145 (35%), Gaps = 21/145 (14%)
Query: 310 TELASPCDNGRCINTHGG-FECECELGYVL--DATAQRCLDNRRGSCWRRVVDGQCEAAA 366
+E S C + N H G F CEC GY + T +D R + CE
Sbjct: 714 SEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPIN--------YCETGL 765
Query: 367 PELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT 426
+ Q C GS GF+ DG C+DVDEC S
Sbjct: 766 HNCDIPQRAQCIY--TGGSSYTCSCL------PGFSG-DGQACQDVDECQPS-RCHPDAF 815
Query: 427 CVNTDGSYRCDCPPGLTLDSTGTAP 451
C NT GS+ C C PG D P
Sbjct: 816 CYNTPGSFTCQCKPGYQGDGFRCVP 840
Score = 31.5 bits (68), Expect = 6.3
Identities = 12/35 (34%), Positives = 18/35 (51%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECR 43
+ C N G F C CKPGY+ + +V++ R
Sbjct: 813 DAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTR 847
>M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein.
Length = 1247
Score = 94.3 bits (224), Expect = 8e-19
Identities = 56/169 (33%), Positives = 80/169 (47%), Gaps = 19/169 (11%)
Query: 5 GMCTNGICK-NIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G TN C+ F C C G+ +G C D+DEC + P VC C N G++
Sbjct: 678 GCDTNAACRPGPRTQFTCECSIGFRG--DGRTCYDIDECSEQPSVCGSHTICNNHPGTFR 735
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGG----------RCVNSEGS-FQCVCEAGYRP 111
C C G+ + G C V + + C+ G +C+ + GS + C C G+
Sbjct: 736 CECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF-- 793
Query: 112 TATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
+ AC DVDEC+ R + C+NTPGSF C+C PG+ DG C+
Sbjct: 794 SGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRCV 840
Score = 76.2 bits (179), Expect = 2e-13
Identities = 53/166 (31%), Positives = 73/166 (43%), Gaps = 26/166 (15%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ-RVCRNGR-CHNTPG 140
C ++ C+ G F C C G+R C D+DEC EQ VC + C+N PG
Sbjct: 679 CDTNAACRPG----PRTQFTCECSIGFRGDGR--TCYDIDECSEQPSVCGSHTICNNHPG 732
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQA------------CPAQGSELYAVLCPE 187
+FRCEC+ G+ S++G TC+ + ++ C+ C G Y C
Sbjct: 733 TFRCECVEGYQFSDEG-TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLP 791
Query: 188 GPSKDNGGA-DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPD 231
G S D D++EC P C P C N + C C PGY D
Sbjct: 792 GFSGDGQACQDVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGD 835
Score = 54.8 bits (126), Expect = 6e-07
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 13/100 (13%)
Query: 197 DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDADGLC------RDIDECDMHQSYC 249
DI+EC+ P C H C N +RC C GY +G C R I+ C+ C
Sbjct: 710 DIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNC 769
Query: 250 ---AGGQCRNTAG-SFTCVCPEGTRHEPELQLCRDIDECE 285
QC T G S+TC C G + Q C+D+DEC+
Sbjct: 770 DIPQRAQCIYTGGSSYTCSCLPG--FSGDGQACQDVDECQ 807
Score = 50.0 bits (114), Expect = 2e-05
Identities = 53/183 (28%), Positives = 65/183 (35%), Gaps = 41/183 (22%)
Query: 111 PTATRGAC-VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK------ 163
P A + C + C+ CR G F CEC GF DGRTC +
Sbjct: 665 PDALQNPCYIGTHGCDTNAACRPG----PRTQFTCECSIGFR--GDGRTCYDIDECSEQP 718
Query: 164 --LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCE----NLE 217
G C P + C EG + G C AV P CE N +
Sbjct: 719 SVCGSHTICNNHPGT----FRCECVEGYQFSDEGT----CVAVVDQRPINYCETGLHNCD 770
Query: 218 ------------PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
Y C C PG+ D C+D+DEC + + C NT GSFTC C
Sbjct: 771 IPQRAQCIYTGGSSYTCSCLPGFSGDGQA-CQDVDECQPSRCH-PDAFCYNTPGSFTCQC 828
Query: 266 PEG 268
G
Sbjct: 829 KPG 831
Score = 46.8 bits (106), Expect = 2e-04
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPGLTLDSTGT 449
DG TC D+DEC+ +C T C N G++RC+C G GT
Sbjct: 704 DGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGT 749
Score = 46.0 bits (104), Expect = 3e-04
Identities = 37/130 (28%), Positives = 50/130 (38%), Gaps = 20/130 (15%)
Query: 220 YRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLC 278
+ C C G+ D C DIDEC S C C N G+F C C EG + E
Sbjct: 693 FTCECSIGFRGDGR-TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCV 751
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYV 337
+D + +Y E+ DIP +CI T G + C C G+
Sbjct: 752 AVVD----QRPINYCETGLHNCDIP-------------QRAQCIYTGGSSYTCSCLPGFS 794
Query: 338 LDATAQRCLD 347
D A + +D
Sbjct: 795 GDGQACQDVD 804
Score = 43.2 bits (97), Expect = 0.002
Identities = 43/145 (29%), Positives = 52/145 (35%), Gaps = 21/145 (14%)
Query: 310 TELASPCDNGRCINTHGG-FECECELGYVL--DATAQRCLDNRRGSCWRRVVDGQCEAAA 366
+E S C + N H G F CEC GY + T +D R + CE
Sbjct: 715 SEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPIN--------YCETGL 766
Query: 367 PELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT 426
+ Q C GS GF+ DG C+DVDEC S
Sbjct: 767 HNCDIPQRAQCIY--TGGSSYTCSCL------PGFSG-DGQACQDVDECQPS-RCHPDAF 816
Query: 427 CVNTDGSYRCDCPPGLTLDSTGTAP 451
C NT GS+ C C PG D P
Sbjct: 817 CYNTPGSFTCQCKPGYQGDGFRCVP 841
Score = 31.5 bits (68), Expect = 6.3
Identities = 12/35 (34%), Positives = 18/35 (51%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECR 43
+ C N G F C CKPGY+ + +V++ R
Sbjct: 814 DAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTR 848
>M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein.
Length = 581
Score = 94.3 bits (224), Expect = 8e-19
Identities = 56/169 (33%), Positives = 80/169 (47%), Gaps = 19/169 (11%)
Query: 5 GMCTNGICK-NIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G TN C+ F C C G+ +G C D+DEC + P VC C N G++
Sbjct: 12 GCDTNAACRPGPRTQFTCECSIGFRG--DGRTCYDIDECSEQPSVCGSHTICNNHPGTFR 69
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGG----------RCVNSEGS-FQCVCEAGYRP 111
C C G+ + G C V + + C+ G +C+ + GS + C C G+
Sbjct: 70 CECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF-- 127
Query: 112 TATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
+ AC DVDEC+ R + C+NTPGSF C+C PG+ DG C+
Sbjct: 128 SGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRCV 174
Score = 76.2 bits (179), Expect = 2e-13
Identities = 53/166 (31%), Positives = 73/166 (43%), Gaps = 26/166 (15%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ-RVCRNGR-CHNTPG 140
C ++ C+ G F C C G+R C D+DEC EQ VC + C+N PG
Sbjct: 13 CDTNAACRPG----PRTQFTCECSIGFRGDGR--TCYDIDECSEQPSVCGSHTICNNHPG 66
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQA------------CPAQGSELYAVLCPE 187
+FRCEC+ G+ S++G TC+ + ++ C+ C G Y C
Sbjct: 67 TFRCECVEGYQFSDEG-TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLP 125
Query: 188 GPSKDNGGA-DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPD 231
G S D D++EC P C P C N + C C PGY D
Sbjct: 126 GFSGDGQACQDVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGD 169
Score = 54.8 bits (126), Expect = 6e-07
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 13/100 (13%)
Query: 197 DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDADGLC------RDIDECDMHQSYC 249
DI+EC+ P C H C N +RC C GY +G C R I+ C+ C
Sbjct: 44 DIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNC 103
Query: 250 ---AGGQCRNTAG-SFTCVCPEGTRHEPELQLCRDIDECE 285
QC T G S+TC C G + Q C+D+DEC+
Sbjct: 104 DIPQRAQCIYTGGSSYTCSCLPG--FSGDGQACQDVDECQ 141
Score = 47.6 bits (108), Expect = 9e-05
Identities = 49/162 (30%), Positives = 59/162 (36%), Gaps = 37/162 (22%)
Query: 132 NGRCHNTPGS-FRCECLPGFTLSNDGRTCLGLK--------LGWGVSCQACPAQGSELYA 182
N C P + F CEC GF DGRTC + G C P +
Sbjct: 16 NAACRPGPRTQFTCECSIGFR--GDGRTCYDIDECSEQPSVCGSHTICNNHPGT----FR 69
Query: 183 VLCPEGPSKDNGGADINECTAVPGACPHGSCE----NLE------------PGYRCICDP 226
C EG + G C AV P CE N + Y C C P
Sbjct: 70 CECVEGYQFSDEGT----CVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLP 125
Query: 227 GYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
G+ D C+D+DEC + + C NT GSFTC C G
Sbjct: 126 GFSGDGQA-CQDVDECQPSRCH-PDAFCYNTPGSFTCQCKPG 165
Score = 46.8 bits (106), Expect = 2e-04
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPGLTLDSTGT 449
DG TC D+DEC+ +C T C N G++RC+C G GT
Sbjct: 38 DGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGT 83
Score = 46.0 bits (104), Expect = 3e-04
Identities = 37/130 (28%), Positives = 50/130 (38%), Gaps = 20/130 (15%)
Query: 220 YRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLC 278
+ C C G+ D C DIDEC S C C N G+F C C EG + E
Sbjct: 27 FTCECSIGFRGDGR-TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCV 85
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYV 337
+D + +Y E+ DIP +CI T G + C C G+
Sbjct: 86 AVVD----QRPINYCETGLHNCDIP-------------QRAQCIYTGGSSYTCSCLPGFS 128
Query: 338 LDATAQRCLD 347
D A + +D
Sbjct: 129 GDGQACQDVD 138
Score = 43.2 bits (97), Expect = 0.002
Identities = 43/145 (29%), Positives = 52/145 (35%), Gaps = 21/145 (14%)
Query: 310 TELASPCDNGRCINTHGG-FECECELGYVL--DATAQRCLDNRRGSCWRRVVDGQCEAAA 366
+E S C + N H G F CEC GY + T +D R + CE
Sbjct: 49 SEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPIN--------YCETGL 100
Query: 367 PELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT 426
+ Q C GS GF+ DG C+DVDEC S
Sbjct: 101 HNCDIPQRAQCIY--TGGSSYTCSCL------PGFSG-DGQACQDVDECQPS-RCHPDAF 150
Query: 427 CVNTDGSYRCDCPPGLTLDSTGTAP 451
C NT GS+ C C PG D P
Sbjct: 151 CYNTPGSFTCQCKPGYQGDGFRCVP 175
Score = 31.5 bits (68), Expect = 6.3
Identities = 12/35 (34%), Positives = 18/35 (51%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECR 43
+ C N G F C CKPGY+ + +V++ R
Sbjct: 148 DAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTR 182
>AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein.
Length = 1247
Score = 94.3 bits (224), Expect = 8e-19
Identities = 56/169 (33%), Positives = 80/169 (47%), Gaps = 19/169 (11%)
Query: 5 GMCTNGICK-NIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G TN C+ F C C G+ +G C D+DEC + P VC C N G++
Sbjct: 678 GCDTNAACRPGPRTQFTCECSIGFRG--DGRTCYDIDECSEQPSVCGSHTICNNHPGTFR 735
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGG----------RCVNSEGS-FQCVCEAGYRP 111
C C G+ + G C V + + C+ G +C+ + GS + C C G+
Sbjct: 736 CECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF-- 793
Query: 112 TATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
+ AC DVDEC+ R + C+NTPGSF C+C PG+ DG C+
Sbjct: 794 SGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRCV 840
Score = 76.2 bits (179), Expect = 2e-13
Identities = 53/166 (31%), Positives = 73/166 (43%), Gaps = 26/166 (15%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ-RVCRNGR-CHNTPG 140
C ++ C+ G F C C G+R C D+DEC EQ VC + C+N PG
Sbjct: 679 CDTNAACRPG----PRTQFTCECSIGFRGDGR--TCYDIDECSEQPSVCGSHTICNNHPG 732
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQA------------CPAQGSELYAVLCPE 187
+FRCEC+ G+ S++G TC+ + ++ C+ C G Y C
Sbjct: 733 TFRCECVEGYQFSDEG-TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLP 791
Query: 188 GPSKDNGGA-DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPD 231
G S D D++EC P C P C N + C C PGY D
Sbjct: 792 GFSGDGQACQDVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGD 835
Score = 54.8 bits (126), Expect = 6e-07
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 13/100 (13%)
Query: 197 DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDADGLC------RDIDECDMHQSYC 249
DI+EC+ P C H C N +RC C GY +G C R I+ C+ C
Sbjct: 710 DIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNC 769
Query: 250 ---AGGQCRNTAG-SFTCVCPEGTRHEPELQLCRDIDECE 285
QC T G S+TC C G + Q C+D+DEC+
Sbjct: 770 DIPQRAQCIYTGGSSYTCSCLPG--FSGDGQACQDVDECQ 807
Score = 50.0 bits (114), Expect = 2e-05
Identities = 53/183 (28%), Positives = 65/183 (35%), Gaps = 41/183 (22%)
Query: 111 PTATRGAC-VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK------ 163
P A + C + C+ CR G F CEC GF DGRTC +
Sbjct: 665 PDALQNPCYIGTHGCDTNAACRPG----PRTQFTCECSIGFR--GDGRTCYDIDECSEQP 718
Query: 164 --LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCE----NLE 217
G C P + C EG + G C AV P CE N +
Sbjct: 719 SVCGSHTICNNHPGT----FRCECVEGYQFSDEGT----CVAVVDQRPINYCETGLHNCD 770
Query: 218 ------------PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
Y C C PG+ D C+D+DEC + + C NT GSFTC C
Sbjct: 771 IPQRAQCIYTGGSSYTCSCLPGFSGDGQA-CQDVDECQPSRCH-PDAFCYNTPGSFTCQC 828
Query: 266 PEG 268
G
Sbjct: 829 KPG 831
Score = 46.8 bits (106), Expect = 2e-04
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPGLTLDSTGT 449
DG TC D+DEC+ +C T C N G++RC+C G GT
Sbjct: 704 DGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGT 749
Score = 46.0 bits (104), Expect = 3e-04
Identities = 37/130 (28%), Positives = 50/130 (38%), Gaps = 20/130 (15%)
Query: 220 YRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLC 278
+ C C G+ D C DIDEC S C C N G+F C C EG + E
Sbjct: 693 FTCECSIGFRGDGR-TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCV 751
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYV 337
+D + +Y E+ DIP +CI T G + C C G+
Sbjct: 752 AVVD----QRPINYCETGLHNCDIP-------------QRAQCIYTGGSSYTCSCLPGFS 794
Query: 338 LDATAQRCLD 347
D A + +D
Sbjct: 795 GDGQACQDVD 804
Score = 43.2 bits (97), Expect = 0.002
Identities = 43/145 (29%), Positives = 52/145 (35%), Gaps = 21/145 (14%)
Query: 310 TELASPCDNGRCINTHGG-FECECELGYVL--DATAQRCLDNRRGSCWRRVVDGQCEAAA 366
+E S C + N H G F CEC GY + T +D R + CE
Sbjct: 715 SEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPIN--------YCETGL 766
Query: 367 PELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT 426
+ Q C GS GF+ DG C+DVDEC S
Sbjct: 767 HNCDIPQRAQCIY--TGGSSYTCSCL------PGFSG-DGQACQDVDECQPS-RCHPDAF 816
Query: 427 CVNTDGSYRCDCPPGLTLDSTGTAP 451
C NT GS+ C C PG D P
Sbjct: 817 CYNTPGSFTCQCKPGYQGDGFRCVP 841
Score = 31.5 bits (68), Expect = 6.3
Identities = 12/35 (34%), Positives = 18/35 (51%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECR 43
+ C N G F C CKPGY+ + +V++ R
Sbjct: 814 DAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTR 848
>AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein.
Length = 1247
Score = 94.3 bits (224), Expect = 8e-19
Identities = 56/169 (33%), Positives = 80/169 (47%), Gaps = 19/169 (11%)
Query: 5 GMCTNGICK-NIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G TN C+ F C C G+ +G C D+DEC + P VC C N G++
Sbjct: 678 GCDTNAACRPGPRTQFTCECSIGFRG--DGRTCYDIDECSEQPSVCGSHTICNNHPGTFR 735
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGG----------RCVNSEGS-FQCVCEAGYRP 111
C C G+ + G C V + + C+ G +C+ + GS + C C G+
Sbjct: 736 CECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF-- 793
Query: 112 TATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
+ AC DVDEC+ R + C+NTPGSF C+C PG+ DG C+
Sbjct: 794 SGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRCV 840
Score = 76.2 bits (179), Expect = 2e-13
Identities = 53/166 (31%), Positives = 73/166 (43%), Gaps = 26/166 (15%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ-RVCRNGR-CHNTPG 140
C ++ C+ G F C C G+R C D+DEC EQ VC + C+N PG
Sbjct: 679 CDTNAACRPG----PRTQFTCECSIGFRGDGR--TCYDIDECSEQPSVCGSHTICNNHPG 732
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQA------------CPAQGSELYAVLCPE 187
+FRCEC+ G+ S++G TC+ + ++ C+ C G Y C
Sbjct: 733 TFRCECVEGYQFSDEG-TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLP 791
Query: 188 GPSKDNGGA-DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPD 231
G S D D++EC P C P C N + C C PGY D
Sbjct: 792 GFSGDGQACQDVDECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGD 835
Score = 54.8 bits (126), Expect = 6e-07
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 13/100 (13%)
Query: 197 DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDADGLC------RDIDECDMHQSYC 249
DI+EC+ P C H C N +RC C GY +G C R I+ C+ C
Sbjct: 710 DIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNC 769
Query: 250 ---AGGQCRNTAG-SFTCVCPEGTRHEPELQLCRDIDECE 285
QC T G S+TC C G + Q C+D+DEC+
Sbjct: 770 DIPQRAQCIYTGGSSYTCSCLPG--FSGDGQACQDVDECQ 807
Score = 50.0 bits (114), Expect = 2e-05
Identities = 53/183 (28%), Positives = 65/183 (35%), Gaps = 41/183 (22%)
Query: 111 PTATRGAC-VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK------ 163
P A + C + C+ CR G F CEC GF DGRTC +
Sbjct: 665 PDALQNPCYIGTHGCDTNAACRPG----PRTQFTCECSIGFR--GDGRTCYDIDECSEQP 718
Query: 164 --LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCE----NLE 217
G C P + C EG + G C AV P CE N +
Sbjct: 719 SVCGSHTICNNHPGT----FRCECVEGYQFSDEGT----CVAVVDQRPINYCETGLHNCD 770
Query: 218 ------------PGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVC 265
Y C C PG+ D C+D+DEC + + C NT GSFTC C
Sbjct: 771 IPQRAQCIYTGGSSYTCSCLPGFSGDGQA-CQDVDECQPSRCH-PDAFCYNTPGSFTCQC 828
Query: 266 PEG 268
G
Sbjct: 829 KPG 831
Score = 46.8 bits (106), Expect = 2e-04
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPGLTLDSTGT 449
DG TC D+DEC+ +C T C N G++RC+C G GT
Sbjct: 704 DGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGT 749
Score = 46.0 bits (104), Expect = 3e-04
Identities = 37/130 (28%), Positives = 50/130 (38%), Gaps = 20/130 (15%)
Query: 220 YRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLC 278
+ C C G+ D C DIDEC S C C N G+F C C EG + E
Sbjct: 693 FTCECSIGFRGDGR-TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCV 751
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYV 337
+D + +Y E+ DIP +CI T G + C C G+
Sbjct: 752 AVVD----QRPINYCETGLHNCDIP-------------QRAQCIYTGGSSYTCSCLPGFS 794
Query: 338 LDATAQRCLD 347
D A + +D
Sbjct: 795 GDGQACQDVD 804
Score = 43.2 bits (97), Expect = 0.002
Identities = 43/145 (29%), Positives = 52/145 (35%), Gaps = 21/145 (14%)
Query: 310 TELASPCDNGRCINTHGG-FECECELGYVL--DATAQRCLDNRRGSCWRRVVDGQCEAAA 366
+E S C + N H G F CEC GY + T +D R + CE
Sbjct: 715 SEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPIN--------YCETGL 766
Query: 367 PELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT 426
+ Q C GS GF+ DG C+DVDEC S
Sbjct: 767 HNCDIPQRAQCIY--TGGSSYTCSCL------PGFSG-DGQACQDVDECQPS-RCHPDAF 816
Query: 427 CVNTDGSYRCDCPPGLTLDSTGTAP 451
C NT GS+ C C PG D P
Sbjct: 817 CYNTPGSFTCQCKPGYQGDGFRCVP 841
Score = 31.5 bits (68), Expect = 6.3
Identities = 12/35 (34%), Positives = 18/35 (51%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECR 43
+ C N G F C CKPGY+ + +V++ R
Sbjct: 814 DAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTR 848
>AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein.
Length = 723
Score = 94.3 bits (224), Expect = 8e-19
Identities = 70/269 (26%), Positives = 108/269 (40%), Gaps = 28/269 (10%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGR-CRNTA-GSYTC 63
C +G C+ ++C C+ G+ G C +D++ C + + C+ G C NT GSYTC
Sbjct: 263 CLHGTCQQ---PWQCNCQEGWG----GLFCNQDLNYCTHH-KPCKNGATCTNTGQGSYTC 314
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PG+ T A +DEC GG C + E S+ C C G+ +
Sbjct: 315 SCRPGY--TGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICE---LSAMT 369
Query: 124 CEEQRVCRNGRCHNTP-GSFRCECLPGFTLSNDGRT---CLGLKLGWGVSCQACPAQGSE 179
C + GRC ++P G + C C G++ N + C G C +
Sbjct: 370 CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKC----VDLGD 425
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
Y C G S + ++++C + P A G+C + + C C PGY +
Sbjct: 426 AYLCRCQAGFSGRHCDDNVDDCASSPCA-NGGTCRDGVNDFSCTCPPGY--TGRNCSAPV 482
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C+ H G C + C C G
Sbjct: 483 SRCE-HAPCHNGATCHERGHGYVCECARG 510
Score = 83.4 bits (197), Expect = 1e-15
Identities = 51/152 (33%), Positives = 69/152 (45%), Gaps = 21/152 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGS 60
NGG C++ + DGG+ C C GY G C + +D C +P C G +C + +
Sbjct: 377 NGGRCSD----SPDGGYSCRCPVGYS----GFNCEKKIDYCSSSP--CSNGAKCVDLGDA 426
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
Y C C+ GF+ +C D VD+CA+ GG C + F C C GY R
Sbjct: 427 YLCRCQAGFS---GRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY---TGRNCSA 480
Query: 120 DVDECEEQRVCRNGR-CHNTPGSFRCECLPGF 150
V CE C NG CH + CEC G+
Sbjct: 481 PVSRCEHAP-CHNGATCHERGHGYVCECARGY 511
Score = 73.3 bits (172), Expect = 2e-12
Identities = 83/294 (28%), Positives = 121/294 (41%), Gaps = 45/294 (15%)
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C G+ YC DEC C G C + +QC C+ G+ D++
Sbjct: 243 CKCRVGWQ---GRYC---DECIRYPGCLHGTC---QQPWQCNCQEGWGGLFCNQ---DLN 290
Query: 123 ECEEQRVCRNGR-CHNT-PGSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQ---ACPAQ 176
C + C+NG C NT GS+ C C PG+T G TC LG+ C+ +C
Sbjct: 291 YCTHHKPCKNGATCTNTGQGSYTCSCRPGYT----GATCELGIDECDPSPCKNGGSCTDL 346
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-C-ENLEPGYRCICDPGYHPDADG 234
+ Y+ CP P +++ T G C +G C ++ + GY C C GY
Sbjct: 347 ENS-YSCTCP--PGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGY--SGFN 401
Query: 235 LCRDIDECDMHQSYCAGG-QCRNTAGSFTCVCPEGT--RH-EPELQLCRDIDECEGETET 290
+ ID C S C+ G +C + ++ C C G RH + + C G T
Sbjct: 402 CEKKIDYCS--SSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCR 459
Query: 291 HYIESDYERGDIPPTFPTRTELA-------SPCDNGRCINTHG-GFECECELGY 336
+ +D+ PP + R A +PC NG + G G+ CEC GY
Sbjct: 460 DGV-NDFSC-TCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHGYVCECARGY 511
Score = 56.0 bits (129), Expect = 3e-07
Identities = 75/257 (29%), Positives = 104/257 (40%), Gaps = 41/257 (15%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-C-RDIDECDMHQSYCAGG 252
G +EC PG C HG+C+ +P ++C C G+ GL C +D++ C H+ G
Sbjct: 251 GRYCDECIRYPG-CLHGTCQ--QP-WQCNCQEGW----GGLFCNQDLNYCTHHKPCKNGA 302
Query: 253 QCRNTA-GSFTCVC-PEGTRHEPELQLCR-DIDECEGETETHYIESDYERGDIPPTFPTR 309
C NT GS+TC C P T EL + D C+ +E+ Y P +
Sbjct: 303 TCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKI 362
Query: 310 TEL-ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPE 368
EL A C +G C +GG RC D+ G R G +
Sbjct: 363 CELSAMTCADGPCF--NGG----------------RCSDSPDGGYSCRCPVGYSGFNCEK 404
Query: 369 LLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRD-VDECALSAELCA-GGT 426
+ + C S + G+ + A G C D VD+CA S CA GGT
Sbjct: 405 KI---DYCSSSPCSNGAKCVDLGDAYLCRCQ--AGFSGRHCDDNVDDCASSP--CANGGT 457
Query: 427 CVNTDGSYRCDCPPGLT 443
C + + C CPPG T
Sbjct: 458 CRDGVNDFSCTCPPGYT 474
>AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein.
Length = 723
Score = 94.3 bits (224), Expect = 8e-19
Identities = 70/269 (26%), Positives = 108/269 (40%), Gaps = 28/269 (10%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGR-CRNTA-GSYTC 63
C +G C+ ++C C+ G+ G C +D++ C + + C+ G C NT GSYTC
Sbjct: 263 CLHGTCQQ---PWQCNCQEGWG----GLFCNQDLNYCTHH-KPCKNGATCTNTGQGSYTC 314
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PG+ T A +DEC GG C + E S+ C C G+ +
Sbjct: 315 SCRPGY--TGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICE---LSAMT 369
Query: 124 CEEQRVCRNGRCHNTP-GSFRCECLPGFTLSNDGRT---CLGLKLGWGVSCQACPAQGSE 179
C + GRC ++P G + C C G++ N + C G C +
Sbjct: 370 CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKC----VDLGD 425
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
Y C G S + ++++C + P A G+C + + C C PGY +
Sbjct: 426 AYLCRCQAGFSGRHCDDNVDDCASSPCA-NGGTCRDGVNDFSCTCPPGY--TGRNCSAPV 482
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C+ H G C + C C G
Sbjct: 483 SRCE-HAPCHNGATCHERGHGYVCECARG 510
Score = 83.4 bits (197), Expect = 1e-15
Identities = 51/152 (33%), Positives = 69/152 (45%), Gaps = 21/152 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGS 60
NGG C++ + DGG+ C C GY G C + +D C +P C G +C + +
Sbjct: 377 NGGRCSD----SPDGGYSCRCPVGYS----GFNCEKKIDYCSSSP--CSNGAKCVDLGDA 426
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
Y C C+ GF+ +C D VD+CA+ GG C + F C C GY R
Sbjct: 427 YLCRCQAGFS---GRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY---TGRNCSA 480
Query: 120 DVDECEEQRVCRNGR-CHNTPGSFRCECLPGF 150
V CE C NG CH + CEC G+
Sbjct: 481 PVSRCEHAP-CHNGATCHERGHGYVCECARGY 511
Score = 73.3 bits (172), Expect = 2e-12
Identities = 83/294 (28%), Positives = 121/294 (41%), Gaps = 45/294 (15%)
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD 122
C C G+ YC DEC C G C + +QC C+ G+ D++
Sbjct: 243 CKCRVGWQ---GRYC---DECIRYPGCLHGTC---QQPWQCNCQEGWGGLFCNQ---DLN 290
Query: 123 ECEEQRVCRNGR-CHNT-PGSFRCECLPGFTLSNDGRTC-LGLKLGWGVSCQ---ACPAQ 176
C + C+NG C NT GS+ C C PG+T G TC LG+ C+ +C
Sbjct: 291 YCTHHKPCKNGATCTNTGQGSYTCSCRPGYT----GATCELGIDECDPSPCKNGGSCTDL 346
Query: 177 GSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-C-ENLEPGYRCICDPGYHPDADG 234
+ Y+ CP P +++ T G C +G C ++ + GY C C GY
Sbjct: 347 ENS-YSCTCP--PGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGY--SGFN 401
Query: 235 LCRDIDECDMHQSYCAGG-QCRNTAGSFTCVCPEGT--RH-EPELQLCRDIDECEGETET 290
+ ID C S C+ G +C + ++ C C G RH + + C G T
Sbjct: 402 CEKKIDYCS--SSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCR 459
Query: 291 HYIESDYERGDIPPTFPTRTELA-------SPCDNGRCINTHG-GFECECELGY 336
+ +D+ PP + R A +PC NG + G G+ CEC GY
Sbjct: 460 DGV-NDFSC-TCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHGYVCECARGY 511
Score = 56.0 bits (129), Expect = 3e-07
Identities = 75/257 (29%), Positives = 104/257 (40%), Gaps = 41/257 (15%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-C-RDIDECDMHQSYCAGG 252
G +EC PG C HG+C+ +P ++C C G+ GL C +D++ C H+ G
Sbjct: 251 GRYCDECIRYPG-CLHGTCQ--QP-WQCNCQEGW----GGLFCNQDLNYCTHHKPCKNGA 302
Query: 253 QCRNTA-GSFTCVC-PEGTRHEPELQLCR-DIDECEGETETHYIESDYERGDIPPTFPTR 309
C NT GS+TC C P T EL + D C+ +E+ Y P +
Sbjct: 303 TCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKI 362
Query: 310 TEL-ASPCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPE 368
EL A C +G C +GG RC D+ G R G +
Sbjct: 363 CELSAMTCADGPCF--NGG----------------RCSDSPDGGYSCRCPVGYSGFNCEK 404
Query: 369 LLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRD-VDECALSAELCA-GGT 426
+ + C S + G+ + A G C D VD+CA S CA GGT
Sbjct: 405 KI---DYCSSSPCSNGAKCVDLGDAYLCRCQ--AGFSGRHCDDNVDDCASSP--CANGGT 457
Query: 427 CVNTDGSYRCDCPPGLT 443
C + + C CPPG T
Sbjct: 458 CRDGVNDFSCTCPPGYT 474
>AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein.
Length = 723
Score = 93.9 bits (223), Expect = 1e-18
Identities = 70/269 (26%), Positives = 108/269 (40%), Gaps = 28/269 (10%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGR-CRNTA-GSYTC 63
C +G C+ ++C C+ G+ G C +D++ C + + C+ G C NT GSYTC
Sbjct: 263 CLHGTCQQ---PWQCNCQEGWG----GLFCNQDLNYCTHH-KPCKNGATCTNTGQGSYTC 314
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PG+ T A +DEC GG C + E S+ C C G+ +
Sbjct: 315 SCRPGY--TGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICE---LSAMT 369
Query: 124 CEEQRVCRNGRCHNTP-GSFRCECLPGFTLSNDGRT---CLGLKLGWGVSCQACPAQGSE 179
C + GRC ++P G + C C G++ N + C G C +
Sbjct: 370 CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKC----VDLGD 425
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
Y C G S + ++++C + P A G+C + + C C PGY +
Sbjct: 426 AYLCRCQAGFSGRHCDDNVDDCASSPCA-NGGTCRDGVNDFSCTCPPGY--TGRNCSAPV 482
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C+ H G C + C C G
Sbjct: 483 SRCE-HAPCHNGATCHERGHRYVCECARG 510
Score = 83.0 bits (196), Expect = 2e-15
Identities = 51/152 (33%), Positives = 69/152 (45%), Gaps = 21/152 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGS 60
NGG C++ + DGG+ C C GY G C + +D C +P C G +C + +
Sbjct: 377 NGGRCSD----SPDGGYSCRCPVGYS----GFNCEKKIDYCSSSP--CSNGAKCVDLGDA 426
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
Y C C+ GF+ +C D VD+CA+ GG C + F C C GY R
Sbjct: 427 YLCRCQAGFS---GRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY---TGRNCSA 480
Query: 120 DVDECEEQRVCRNGR-CHNTPGSFRCECLPGF 150
V CE C NG CH + CEC G+
Sbjct: 481 PVSRCEHAP-CHNGATCHERGHRYVCECARGY 511
Score = 60.1 bits (139), Expect = 2e-08
Identities = 51/155 (32%), Positives = 74/155 (47%), Gaps = 21/155 (13%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-C-RDIDECDMHQSYCAGG 252
G +EC PG C HG+C+ +P ++C C G+ GL C +D++ C H+ G
Sbjct: 251 GRYCDECIRYPG-CLHGTCQ--QP-WQCNCQEGW----GGLFCNQDLNYCTHHKPCKNGA 302
Query: 253 QCRNTA-GSFTCVCPEG-TRHEPELQLCR-DIDECEGETETHYIESDYERGDIPPTFPTR 309
C NT GS+TC C G T EL + D C+ +E+ Y P +
Sbjct: 303 TCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKI 362
Query: 310 TELAS------PCDNG-RCINT-HGGFECECELGY 336
EL++ PC NG RC ++ GG+ C C +GY
Sbjct: 363 CELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGY 397
Score = 39.5 bits (88), Expect = 0.024
Identities = 19/38 (50%), Positives = 23/38 (60%), Gaps = 4/38 (10%)
Query: 406 GATCR-DVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
GATC +DEC S C GG+C + + SY C CPPG
Sbjct: 322 GATCELGIDECDPSP--CKNGGSCTDLENSYSCTCPPG 357
Score = 33.9 bits (74), Expect = 1.2
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 2/40 (5%)
Query: 406 GATC-RDVDECALSAELCAGGTCVNT-DGSYRCDCPPGLT 443
G C +D++ C G TC NT GSY C C PG T
Sbjct: 282 GLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYT 321
Score = 31.9 bits (69), Expect = 4.8
Identities = 16/34 (47%), Positives = 16/34 (47%), Gaps = 7/34 (20%)
Query: 415 CALSAELCAGGTCVN-------TDGSYRCDCPPG 441
C LSA CA G C N DG Y C CP G
Sbjct: 363 CELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVG 396
>AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophila)
protein.
Length = 723
Score = 93.9 bits (223), Expect = 1e-18
Identities = 70/269 (26%), Positives = 108/269 (40%), Gaps = 28/269 (10%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGR-CRNTA-GSYTC 63
C +G C+ ++C C+ G+ G C +D++ C + + C+ G C NT GSYTC
Sbjct: 263 CLHGTCQQ---PWQCNCQEGWG----GLFCNQDLNYCTHH-KPCKNGATCTNTGQGSYTC 314
Query: 64 LCEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDE 123
C PG+ T A +DEC GG C + E S+ C C G+ +
Sbjct: 315 SCRPGY--TGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICE---LSAMT 369
Query: 124 CEEQRVCRNGRCHNTP-GSFRCECLPGFTLSNDGRT---CLGLKLGWGVSCQACPAQGSE 179
C + GRC ++P G + C C G++ N + C G C +
Sbjct: 370 CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKC----VDLGD 425
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDI 239
Y C G S + ++++C + P A G+C + + C C PGY +
Sbjct: 426 AYLCRCQAGFSGRHCDDNVDDCASSPCA-NGGTCRDGVNDFSCTCPPGY--TGRNCSAPV 482
Query: 240 DECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
C+ H G C + C C G
Sbjct: 483 SRCE-HAPCHNGATCHERGHRYVCECARG 510
Score = 83.0 bits (196), Expect = 2e-15
Identities = 51/152 (33%), Positives = 69/152 (45%), Gaps = 21/152 (13%)
Query: 3 NGGMCTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRG-RCRNTAGS 60
NGG C++ + DGG+ C C GY G C + +D C +P C G +C + +
Sbjct: 377 NGGRCSD----SPDGGYSCRCPVGYS----GFNCEKKIDYCSSSP--CSNGAKCVDLGDA 426
Query: 61 YTCLCEPGFAPTAAGYCAD-VDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV 119
Y C C+ GF+ +C D VD+CA+ GG C + F C C GY R
Sbjct: 427 YLCRCQAGFS---GRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY---TGRNCSA 480
Query: 120 DVDECEEQRVCRNGR-CHNTPGSFRCECLPGF 150
V CE C NG CH + CEC G+
Sbjct: 481 PVSRCEHAP-CHNGATCHERGHRYVCECARGY 511
Score = 60.1 bits (139), Expect = 2e-08
Identities = 51/155 (32%), Positives = 74/155 (47%), Gaps = 21/155 (13%)
Query: 195 GADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGL-C-RDIDECDMHQSYCAGG 252
G +EC PG C HG+C+ +P ++C C G+ GL C +D++ C H+ G
Sbjct: 251 GRYCDECIRYPG-CLHGTCQ--QP-WQCNCQEGW----GGLFCNQDLNYCTHHKPCKNGA 302
Query: 253 QCRNTA-GSFTCVCPEG-TRHEPELQLCR-DIDECEGETETHYIESDYERGDIPPTFPTR 309
C NT GS+TC C G T EL + D C+ +E+ Y P +
Sbjct: 303 TCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKI 362
Query: 310 TELAS------PCDNG-RCINT-HGGFECECELGY 336
EL++ PC NG RC ++ GG+ C C +GY
Sbjct: 363 CELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGY 397
Score = 39.5 bits (88), Expect = 0.024
Identities = 19/38 (50%), Positives = 23/38 (60%), Gaps = 4/38 (10%)
Query: 406 GATCR-DVDECALSAELCA-GGTCVNTDGSYRCDCPPG 441
GATC +DEC S C GG+C + + SY C CPPG
Sbjct: 322 GATCELGIDECDPSP--CKNGGSCTDLENSYSCTCPPG 357
Score = 33.9 bits (74), Expect = 1.2
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 2/40 (5%)
Query: 406 GATC-RDVDECALSAELCAGGTCVNT-DGSYRCDCPPGLT 443
G C +D++ C G TC NT GSY C C PG T
Sbjct: 282 GLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYT 321
Score = 31.9 bits (69), Expect = 4.8
Identities = 16/34 (47%), Positives = 16/34 (47%), Gaps = 7/34 (20%)
Query: 415 CALSAELCAGGTCVN-------TDGSYRCDCPPG 441
C LSA CA G C N DG Y C CP G
Sbjct: 363 CELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVG 396
>AK027775-1|BAB55358.1| 537|Homo sapiens protein ( Homo sapiens
cDNA FLJ14869 fis, clone PLACE1002474, moderately
similar to Mus musculus matrilin-2 precursor mRNA. ).
Length = 537
Score = 93.9 bits (223), Expect = 1e-18
Identities = 64/228 (28%), Positives = 88/228 (38%), Gaps = 12/228 (5%)
Query: 15 IDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA- 73
++ + C C GY G C VD C C + C NT S+ C C GF
Sbjct: 1 MEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINED 59
Query: 74 AGYCADVDEC-AADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECE-EQRVCR 131
C+ VD C +D C+ CVN + SF C C G+ + C +D C C
Sbjct: 60 LMTCSRVDYCLLSDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE 118
Query: 132 NGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV--SCQACPAQGSELYAVLCPEGP 189
+ C ++ SF C+C G+ L DG+TC + + C+ + Y C EG
Sbjct: 119 HS-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGF 177
Query: 190 SKDNGGADINE---CTAVPGACPHGSCENLEPGYRCICDPGYHPDADG 234
G C + C H C N Y C C G+ DG
Sbjct: 178 RLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDG 224
Score = 92.7 bits (220), Expect = 2e-18
Identities = 67/217 (30%), Positives = 82/217 (37%), Gaps = 11/217 (5%)
Query: 60 SYTCLCEPGFAPTAAGY-CADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGAC 118
SY C C G+ G C+ VD CA C+N+E SF C C G+ C
Sbjct: 4 SYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLMTC 63
Query: 119 VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGL---KLGWGVSCQACPA 175
VD C C N SF C+C G L +DG+TC L LG C+
Sbjct: 64 SRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALG-DHGCEHSCV 122
Query: 176 QGSELYAVLCPEGPSKDNGGADINE---CTAVPGACPHGSCENLEPGYRCICDPGYHPDA 232
+ + C EG G C A+ C H C N + Y C C G+
Sbjct: 123 SSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAE 181
Query: 233 DG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
DG CR D C C C N S+ C C EG
Sbjct: 182 DGKRCRRKDVCKSTHHGCE-HICVNNGNSYICKCSEG 217
Score = 90.2 bits (214), Expect = 1e-17
Identities = 74/254 (29%), Positives = 100/254 (39%), Gaps = 34/254 (13%)
Query: 98 EGSFQCVCEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGR 157
E S+ C C GY C VD C +Q C NT SF C+C GF ++ D
Sbjct: 2 EESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLM 61
Query: 158 TC--LGLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGG---ADINECTAVPGACPHGS 212
TC + L C+ +A CPEG + G A ++ C C H S
Sbjct: 62 TCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-S 120
Query: 213 CENLEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRH 271
C + E + C C GY DG CR D C C C N+ S+TC C EG R
Sbjct: 121 CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCE-HICVNSDDSYTCECLEGFRL 179
Query: 272 EPELQLCRDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECE 331
+ + CR D C+ TH+ C++ C+N + C+
Sbjct: 180 AEDGKRCRRKDVCK---STHH----------------------GCEH-ICVNNGNSYICK 213
Query: 332 CELGYVLDATAQRC 345
C G+VL +RC
Sbjct: 214 CSEGFVLAEDGRRC 227
Score = 90.2 bits (214), Expect = 1e-17
Identities = 61/200 (30%), Positives = 80/200 (40%), Gaps = 8/200 (4%)
Query: 11 ICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFA 70
+C N + F C C G+ + C VD C + C C N S+ C C G
Sbjct: 38 LCLNTEDSFVCQCSEGFLINEDLMTCSRVDYCLLSDHGCEYS-CVNMDRSFACQCPEGHV 96
Query: 71 PTAAG-YCADVDECA-ADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEE-Q 127
+ G CA +D CA D C+ CV+SE SF C C GY C D C+
Sbjct: 97 LRSDGKTCAKLDSCALGDHGCEHS-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAID 155
Query: 128 RVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV--SCQACPAQGSELYAVLC 185
C + C N+ S+ CECL GF L+ DG+ C + C+ Y C
Sbjct: 156 HGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKC 214
Query: 186 PEGPSKDNGGADINECTAVP 205
EG G +CT P
Sbjct: 215 SEGFVLAEDGRRCKKCTEGP 234
Score = 62.9 bits (146), Expect = 2e-09
Identities = 65/249 (26%), Positives = 86/249 (34%), Gaps = 41/249 (16%)
Query: 216 LEPGYRCICDPGYHPDADG-LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEGTRHEPE 274
+E Y C C GY D +G C +D C C C NT SF C C EG +
Sbjct: 1 MEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINED 59
Query: 275 LQLCRDIDECE-GETETHYIESDYERG---DIPPTFPTRTE-----LASPC---DNG--- 319
L C +D C + Y + +R P R++ C D+G
Sbjct: 60 LMTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH 119
Query: 320 RCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQECCCSV 379
C+++ F C+C GY+L + C R+ C + +D CE C C
Sbjct: 120 SCVSSEDSFVCQCFEGYILREDGKTC--RRKDVC--QAIDHGCEHICVNSDDSYTCECLE 175
Query: 380 GLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGTCVNTDGSYRCDCP 439
G DG CR D C + C CVN SY C C
Sbjct: 176 GFRLAE-------------------DGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCS 215
Query: 440 PGLTLDSTG 448
G L G
Sbjct: 216 EGFVLAEDG 224
>AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) variant
protein.
Length = 1241
Score = 93.5 bits (222), Expect = 1e-18
Identities = 56/169 (33%), Positives = 79/169 (46%), Gaps = 19/169 (11%)
Query: 5 GMCTNGICK-NIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYT 62
G TN C+ F C C G+ +G C D+DEC + P VC C N G++
Sbjct: 677 GCDTNAACRPGPRTQFTCECSIGFRG--DGRTCYDIDECSEQPSVCGSHTICNNHPGTFR 734
Query: 63 CLCEPGFAPTAAGYCADVDECAADSMCKGG----------RCVNSEGS-FQCVCEAGYRP 111
C C G+ + G C V + + C+ G +C+ + GS + C C G+
Sbjct: 735 CECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF-- 792
Query: 112 TATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCL 160
+ AC DVDEC R + C+NTPGSF C+C PG+ DG C+
Sbjct: 793 SGDGQACQDVDECHPSRCHPDAFCYNTPGSFTCQCKPGY--QGDGFRCV 839
Score = 75.8 bits (178), Expect = 3e-13
Identities = 53/166 (31%), Positives = 73/166 (43%), Gaps = 26/166 (15%)
Query: 83 CAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ-RVCRNGR-CHNTPG 140
C ++ C+ G F C C G+R C D+DEC EQ VC + C+N PG
Sbjct: 678 CDTNAACRPG----PRTQFTCECSIGFRGDGR--TCYDIDECSEQPSVCGSHTICNNHPG 731
Query: 141 SFRCECLPGFTLSNDGRTCLGLKLGWGVS-CQA------------CPAQGSELYAVLCPE 187
+FRCEC+ G+ S++G TC+ + ++ C+ C G Y C
Sbjct: 732 TFRCECVEGYQFSDEG-TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLP 790
Query: 188 GPSKDNGGA-DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPD 231
G S D D++EC P C P C N + C C PGY D
Sbjct: 791 GFSGDGQACQDVDECH--PSRCHPDAFCYNTPGSFTCQCKPGYQGD 834
Score = 54.0 bits (124), Expect = 1e-06
Identities = 35/99 (35%), Positives = 45/99 (45%), Gaps = 13/99 (13%)
Query: 197 DINECTAVPGAC-PHGSCENLEPGYRCICDPGYHPDADGLC------RDIDECDMHQSYC 249
DI+EC+ P C H C N +RC C GY +G C R I+ C+ C
Sbjct: 709 DIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNC 768
Query: 250 ---AGGQCRNTAG-SFTCVCPEGTRHEPELQLCRDIDEC 284
QC T G S+TC C G + Q C+D+DEC
Sbjct: 769 DIPQRAQCIYTGGSSYTCSCLPG--FSGDGQACQDVDEC 805
Score = 52.4 bits (120), Expect = 3e-06
Identities = 56/184 (30%), Positives = 66/184 (35%), Gaps = 43/184 (23%)
Query: 111 PTATRGAC-VDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLK------ 163
P A + C + C+ CR G F CEC GF DGRTC +
Sbjct: 664 PDALQNPCYIGTHGCDTNAACRPG----PRTQFTCECSIGFR--GDGRTCYDIDECSEQP 717
Query: 164 --LGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCE----NLE 217
G C P + C EG + G C AV P CE N +
Sbjct: 718 SVCGSHTICNNHPGT----FRCECVEGYQFSDEGT----CVAVVDQRPINYCETGLHNCD 769
Query: 218 ------------PGYRCICDPGYHPDADGLCRDIDECDMHQSYC-AGGQCRNTAGSFTCV 264
Y C C PG+ D C+D+DEC H S C C NT GSFTC
Sbjct: 770 IPQRAQCIYTGGSSYTCSCLPGFSGDGQA-CQDVDEC--HPSRCHPDAFCYNTPGSFTCQ 826
Query: 265 CPEG 268
C G
Sbjct: 827 CKPG 830
Score = 46.8 bits (106), Expect = 2e-04
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPGLTLDSTGT 449
DG TC D+DEC+ +C T C N G++RC+C G GT
Sbjct: 703 DGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGT 748
Score = 46.0 bits (104), Expect = 3e-04
Identities = 37/130 (28%), Positives = 50/130 (38%), Gaps = 20/130 (15%)
Query: 220 YRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQ-CRNTAGSFTCVCPEGTRHEPELQLC 278
+ C C G+ D C DIDEC S C C N G+F C C EG + E
Sbjct: 692 FTCECSIGFRGDGR-TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCV 750
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDNGRCINTHG-GFECECELGYV 337
+D + +Y E+ DIP +CI T G + C C G+
Sbjct: 751 AVVD----QRPINYCETGLHNCDIP-------------QRAQCIYTGGSSYTCSCLPGFS 793
Query: 338 LDATAQRCLD 347
D A + +D
Sbjct: 794 GDGQACQDVD 803
Score = 42.7 bits (96), Expect = 0.003
Identities = 43/145 (29%), Positives = 52/145 (35%), Gaps = 21/145 (14%)
Query: 310 TELASPCDNGRCINTHGG-FECECELGYVL--DATAQRCLDNRRGSCWRRVVDGQCEAAA 366
+E S C + N H G F CEC GY + T +D R + CE
Sbjct: 714 SEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPIN--------YCETGL 765
Query: 367 PELLLRQECCCSVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCAGGT 426
+ Q C GS GF+ DG C+DVDEC S
Sbjct: 766 HNCDIPQRAQCIY--TGGSSYTCSCL------PGFSG-DGQACQDVDECHPS-RCHPDAF 815
Query: 427 CVNTDGSYRCDCPPGLTLDSTGTAP 451
C NT GS+ C C PG D P
Sbjct: 816 CYNTPGSFTCQCKPGYQGDGFRCVP 840
Score = 31.5 bits (68), Expect = 6.3
Identities = 12/35 (34%), Positives = 18/35 (51%)
Query: 9 NGICKNIDGGFECICKPGYESGSEGALCRDVDECR 43
+ C N G F C CKPGY+ + +V++ R
Sbjct: 813 DAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTR 847
>BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multiple
6 protein.
Length = 553
Score = 92.7 bits (220), Expect = 2e-18
Identities = 74/215 (34%), Positives = 96/215 (44%), Gaps = 24/215 (11%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV-DVDE 123
C G+ + G C E + CK G CV G +C C GY T C DV+E
Sbjct: 49 CCYGWRRNSKGVC----EATCEPGCKFGECV---GPNKCRCFPGY----TGKTCSQDVNE 97
Query: 124 CE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
C + R C++ RC NT GS++C CL G L D TC+ + ++CQ E
Sbjct: 98 CGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCAMINCQYSCEDTEEGPQ 155
Query: 183 VLCPEGPSK--DNGG--ADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPD-ADGL- 235
LCP + NG DI+EC + CP+ C N Y C C G+ G
Sbjct: 156 CLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRY 215
Query: 236 -CRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEG 268
C DI+EC M C+ C NT GSF C C +G
Sbjct: 216 DCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG 250
Score = 85.8 bits (203), Expect = 3e-16
Identities = 55/140 (39%), Positives = 71/140 (50%), Gaps = 11/140 (7%)
Query: 17 GGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAG 75
G +C C PGY G C +DV+EC PR C+ RC NT GSY C C G
Sbjct: 76 GPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA 130
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVC-EAGYRPTATRGACVDVDECEEQRV-CR-N 132
C + CA + C+ C ++E QC+C +G R C+D+DEC +V C N
Sbjct: 131 TCVNSRTCAMIN-CQYS-CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYN 188
Query: 133 GRCHNTPGSFRCECLPGFTL 152
RC NT GS+ C+C GF L
Sbjct: 189 RRCVNTFGSYYCKCHIGFEL 208
Score = 79.0 bits (186), Expect = 3e-14
Identities = 42/122 (34%), Positives = 61/122 (50%), Gaps = 7/122 (5%)
Query: 12 CKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGF 69
C++ + G +C+C G G C D+DEC +C R C NT GSY C C GF
Sbjct: 147 CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF 206
Query: 70 APT--AAGY-CADVDECAADS-MCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
+ Y C D++EC DS C C N++GSF+C C+ GY+ R + + +
Sbjct: 207 ELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSV 266
Query: 125 EE 126
+E
Sbjct: 267 KE 268
Score = 77.8 bits (183), Expect = 7e-14
Identities = 47/148 (31%), Positives = 69/148 (46%), Gaps = 14/148 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG--- 68
C N G ++C C G+ + A C + C + + C +T CLC
Sbjct: 109 CVNTHGSYKCFCLSGHMLMPD-ATCVNSRTCA---MINCQYSCEDTEEGPQCLCPSSGLR 164
Query: 69 FAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCVCEAGYRPTATRGA--CVDVDEC 124
AP C D+DECA+ + C RCVN+ GS+ C C G+ G C+D++EC
Sbjct: 165 LAPNGRD-CLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC 223
Query: 125 E-EQRVC-RNGRCHNTPGSFRCECLPGF 150
+ C + C NT GSF+C+C G+
Sbjct: 224 TMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 66.5 bits (155), Expect = 2e-10
Identities = 75/254 (29%), Positives = 103/254 (40%), Gaps = 34/254 (13%)
Query: 18 GFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYC 77
G + C G+ S+G V E P C+ G C G C C PG+ T
Sbjct: 44 GTKLACCYGWRRNSKG-----VCEATCEPG-CKFGEC---VGPNKCRCFPGY--TGKTCS 92
Query: 78 ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR--PTATRGACVDVDECEEQRVCRNGRC 135
DV+EC RCVN+ GS++C C +G+ P AT CV+ C C+ C
Sbjct: 93 QDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDAT---CVNSRTCAMIN-CQYS-C 147
Query: 136 HNTPGSFRCEC-LPGFTLSNDGRTCLGLK--LGWGVSC---QACPAQGSELYAVLCPEG- 188
+T +C C G L+ +GR CL + V C + C Y C G
Sbjct: 148 EDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCK-CHIGF 206
Query: 189 ----PSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL-CRDIDEC 242
S DINECT C H +C N + ++C C GY +GL C I E
Sbjct: 207 ELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY--KGNGLRCSAIPEN 264
Query: 243 DMHQSYCAGGQCRN 256
+ + A G ++
Sbjct: 265 SVKEVLRAPGTIKD 278
Score = 63.7 bits (148), Expect = 1e-09
Identities = 71/239 (29%), Positives = 94/239 (39%), Gaps = 43/239 (17%)
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKL 164
C G+R + +G C CE C+ G C G +C C PG+T G+TC
Sbjct: 49 CCYGWRRNS-KGVCEAT--CEPG--CKFGEC---VGPNKCRCFPGYT----GKTCSQDVN 96
Query: 165 GWGVS---CQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR 221
G+ CQ Y C G +N T C + SCE+ E G +
Sbjct: 97 ECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINCQY-SCEDTEEGPQ 155
Query: 222 CIC-DPGYHPDADGL-CRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLC 278
C+C G +G C DIDEC + C +C NT GS+ C C G ELQ
Sbjct: 156 CLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF----ELQ-- 209
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGY 336
YI Y+ DI T + C + C NT G F+C+C+ GY
Sbjct: 210 -------------YISGRYDCIDINEC----TMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 53.6 bits (123), Expect = 1e-06
Identities = 52/167 (31%), Positives = 70/167 (41%), Gaps = 28/167 (16%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAG 259
E T PG C G C + P +C C PGY +D++EC M C +C NT G
Sbjct: 62 EATCEPG-CKFGEC--VGPN-KCRCFPGY--TGKTCSQDVNECGMKPRPCQH-RCVNTHG 114
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGD--IPPTFPTR-------- 309
S+ C C G P+ C + C Y D E G + P+ R
Sbjct: 115 SYKCFCLSGHMLMPD-ATCVNSRTC-AMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDC 172
Query: 310 ---TELASP---CD-NGRCINTHGGFECECELGYVLDATAQR--CLD 347
E AS C N RC+NT G + C+C +G+ L + R C+D
Sbjct: 173 LDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCID 219
Score = 51.2 bits (117), Expect = 7e-06
Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 29/132 (21%)
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
PC + RC+NTHG ++C C G++L A C+++R +C +++ C+ + + +
Sbjct: 104 PCQH-RCVNTHGSYKCFCLSGHMLMPDAT-CVNSR--TC--AMIN--CQYSCEDTEEGPQ 155
Query: 375 CCC-SVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDG 432
C C S GL +G C D+DECA +C CVNT G
Sbjct: 156 CLCPSSGLRLAP-------------------NGRDCLDIDECASGKVICPYNRRCVNTFG 196
Query: 433 SYRCDCPPGLTL 444
SY C C G L
Sbjct: 197 SYYCKCHIGFEL 208
Score = 42.7 bits (96), Expect = 0.003
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 9 NGICKNIDGGFECICKPGYESG--SEGALCRDVDECRDNPRVC-RRGRCRNTAGSYTCLC 65
N C N G + C C G+E S C D++EC + C C NT GS+ C C
Sbjct: 188 NRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKC 247
Query: 66 EPGF 69
+ G+
Sbjct: 248 KQGY 251
Score = 38.7 bits (86), Expect = 0.042
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 401 FAKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
F G TC +DV+EC + C CVNT GSY+C C G
Sbjct: 83 FPGYTGKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSG 123
>AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein.
Length = 338
Score = 92.7 bits (220), Expect = 2e-18
Identities = 74/215 (34%), Positives = 96/215 (44%), Gaps = 24/215 (11%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV-DVDE 123
C G+ + G C E + CK G CV G +C C GY T C DV+E
Sbjct: 49 CCYGWRRNSKGVC----EATCEPGCKFGECV---GPNKCRCFPGY----TGKTCSQDVNE 97
Query: 124 CE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
C + R C++ RC NT GS++C CL G L D TC+ + ++CQ E
Sbjct: 98 CGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCAMINCQYSCEDTEEGPQ 155
Query: 183 VLCPEGPSK--DNGG--ADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPD-ADGL- 235
LCP + NG DI+EC + CP+ C N Y C C G+ G
Sbjct: 156 CLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRY 215
Query: 236 -CRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEG 268
C DI+EC M C+ C NT GSF C C +G
Sbjct: 216 DCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG 250
Score = 85.8 bits (203), Expect = 3e-16
Identities = 55/140 (39%), Positives = 71/140 (50%), Gaps = 11/140 (7%)
Query: 17 GGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAG 75
G +C C PGY G C +DV+EC PR C+ RC NT GSY C C G
Sbjct: 76 GPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA 130
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVC-EAGYRPTATRGACVDVDECEEQRV-CR-N 132
C + CA + C+ C ++E QC+C +G R C+D+DEC +V C N
Sbjct: 131 TCVNSRTCAMIN-CQYS-CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYN 188
Query: 133 GRCHNTPGSFRCECLPGFTL 152
RC NT GS+ C+C GF L
Sbjct: 189 RRCVNTFGSYYCKCHIGFEL 208
Score = 79.0 bits (186), Expect = 3e-14
Identities = 42/122 (34%), Positives = 61/122 (50%), Gaps = 7/122 (5%)
Query: 12 CKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGF 69
C++ + G +C+C G G C D+DEC +C R C NT GSY C C GF
Sbjct: 147 CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF 206
Query: 70 APT--AAGY-CADVDECAADS-MCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
+ Y C D++EC DS C C N++GSF+C C+ GY+ R + + +
Sbjct: 207 ELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSV 266
Query: 125 EE 126
+E
Sbjct: 267 KE 268
Score = 77.8 bits (183), Expect = 7e-14
Identities = 47/148 (31%), Positives = 69/148 (46%), Gaps = 14/148 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG--- 68
C N G ++C C G+ + A C + C + + C +T CLC
Sbjct: 109 CVNTHGSYKCFCLSGHMLMPD-ATCVNSRTCA---MINCQYSCEDTEEGPQCLCPSSGLR 164
Query: 69 FAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCVCEAGYRPTATRGA--CVDVDEC 124
AP C D+DECA+ + C RCVN+ GS+ C C G+ G C+D++EC
Sbjct: 165 LAPNGRD-CLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC 223
Query: 125 E-EQRVC-RNGRCHNTPGSFRCECLPGF 150
+ C + C NT GSF+C+C G+
Sbjct: 224 TMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 66.5 bits (155), Expect = 2e-10
Identities = 75/254 (29%), Positives = 103/254 (40%), Gaps = 34/254 (13%)
Query: 18 GFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYC 77
G + C G+ S+G V E P C+ G C G C C PG+ T
Sbjct: 44 GTKLACCYGWRRNSKG-----VCEATCEPG-CKFGEC---VGPNKCRCFPGY--TGKTCS 92
Query: 78 ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR--PTATRGACVDVDECEEQRVCRNGRC 135
DV+EC RCVN+ GS++C C +G+ P AT CV+ C C+ C
Sbjct: 93 QDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDAT---CVNSRTCAMIN-CQYS-C 147
Query: 136 HNTPGSFRCEC-LPGFTLSNDGRTCLGLK--LGWGVSC---QACPAQGSELYAVLCPEG- 188
+T +C C G L+ +GR CL + V C + C Y C G
Sbjct: 148 EDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCK-CHIGF 206
Query: 189 ----PSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL-CRDIDEC 242
S DINECT C H +C N + ++C C GY +GL C I E
Sbjct: 207 ELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY--KGNGLRCSAIPEN 264
Query: 243 DMHQSYCAGGQCRN 256
+ + A G ++
Sbjct: 265 SVKEVLRAPGTIKD 278
Score = 63.7 bits (148), Expect = 1e-09
Identities = 71/239 (29%), Positives = 94/239 (39%), Gaps = 43/239 (17%)
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKL 164
C G+R + +G C CE C+ G C G +C C PG+T G+TC
Sbjct: 49 CCYGWRRNS-KGVCEAT--CEPG--CKFGEC---VGPNKCRCFPGYT----GKTCSQDVN 96
Query: 165 GWGVS---CQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR 221
G+ CQ Y C G +N T C + SCE+ E G +
Sbjct: 97 ECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINCQY-SCEDTEEGPQ 155
Query: 222 CIC-DPGYHPDADGL-CRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLC 278
C+C G +G C DIDEC + C +C NT GS+ C C G ELQ
Sbjct: 156 CLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF----ELQ-- 209
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGY 336
YI Y+ DI T + C + C NT G F+C+C+ GY
Sbjct: 210 -------------YISGRYDCIDINEC----TMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 53.6 bits (123), Expect = 1e-06
Identities = 52/167 (31%), Positives = 70/167 (41%), Gaps = 28/167 (16%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAG 259
E T PG C G C + P +C C PGY +D++EC M C +C NT G
Sbjct: 62 EATCEPG-CKFGEC--VGPN-KCRCFPGY--TGKTCSQDVNECGMKPRPCQH-RCVNTHG 114
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGD--IPPTFPTR-------- 309
S+ C C G P+ C + C Y D E G + P+ R
Sbjct: 115 SYKCFCLSGHMLMPD-ATCVNSRTC-AMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDC 172
Query: 310 ---TELASP---CD-NGRCINTHGGFECECELGYVLDATAQR--CLD 347
E AS C N RC+NT G + C+C +G+ L + R C+D
Sbjct: 173 LDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCID 219
Score = 51.2 bits (117), Expect = 7e-06
Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 29/132 (21%)
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
PC + RC+NTHG ++C C G++L A C+++R +C +++ C+ + + +
Sbjct: 104 PCQH-RCVNTHGSYKCFCLSGHMLMPDAT-CVNSR--TC--AMIN--CQYSCEDTEEGPQ 155
Query: 375 CCC-SVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDG 432
C C S GL +G C D+DECA +C CVNT G
Sbjct: 156 CLCPSSGLRLAP-------------------NGRDCLDIDECASGKVICPYNRRCVNTFG 196
Query: 433 SYRCDCPPGLTL 444
SY C C G L
Sbjct: 197 SYYCKCHIGFEL 208
Score = 42.7 bits (96), Expect = 0.003
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 9 NGICKNIDGGFECICKPGYESG--SEGALCRDVDECRDNPRVC-RRGRCRNTAGSYTCLC 65
N C N G + C C G+E S C D++EC + C C NT GS+ C C
Sbjct: 188 NRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKC 247
Query: 66 EPGF 69
+ G+
Sbjct: 248 KQGY 251
Score = 38.7 bits (86), Expect = 0.042
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 401 FAKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
F G TC +DV+EC + C CVNT GSY+C C G
Sbjct: 83 FPGYTGKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSG 123
>AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ90733 fis, clone PLACE1010251, highly similar to
Epidermal growth factor-like protein 6 precursor. ).
Length = 553
Score = 92.7 bits (220), Expect = 2e-18
Identities = 74/215 (34%), Positives = 96/215 (44%), Gaps = 24/215 (11%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV-DVDE 123
C G+ + G C E + CK G CV G +C C GY T C DV+E
Sbjct: 49 CCYGWRRNSKGVC----EATCEPGCKFGECV---GPNKCRCFPGY----TGKTCSQDVNE 97
Query: 124 CE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
C + R C++ RC NT GS++C CL G L D TC+ + ++CQ E
Sbjct: 98 CGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCAMINCQYSCEDTEEGPQ 155
Query: 183 VLCPEGPSK--DNGG--ADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPD-ADGL- 235
LCP + NG DI+EC + CP+ C N Y C C G+ G
Sbjct: 156 CLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRY 215
Query: 236 -CRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEG 268
C DI+EC M C+ C NT GSF C C +G
Sbjct: 216 DCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG 250
Score = 85.8 bits (203), Expect = 3e-16
Identities = 55/140 (39%), Positives = 71/140 (50%), Gaps = 11/140 (7%)
Query: 17 GGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAG 75
G +C C PGY G C +DV+EC PR C+ RC NT GSY C C G
Sbjct: 76 GPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA 130
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVC-EAGYRPTATRGACVDVDECEEQRV-CR-N 132
C + CA + C+ C ++E QC+C +G R C+D+DEC +V C N
Sbjct: 131 TCVNSRTCAMIN-CQYS-CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYN 188
Query: 133 GRCHNTPGSFRCECLPGFTL 152
RC NT GS+ C+C GF L
Sbjct: 189 RRCVNTFGSYYCKCHIGFEL 208
Score = 79.0 bits (186), Expect = 3e-14
Identities = 42/122 (34%), Positives = 61/122 (50%), Gaps = 7/122 (5%)
Query: 12 CKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGF 69
C++ + G +C+C G G C D+DEC +C R C NT GSY C C GF
Sbjct: 147 CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF 206
Query: 70 APT--AAGY-CADVDECAADS-MCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
+ Y C D++EC DS C C N++GSF+C C+ GY+ R + + +
Sbjct: 207 ELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSV 266
Query: 125 EE 126
+E
Sbjct: 267 KE 268
Score = 77.8 bits (183), Expect = 7e-14
Identities = 47/148 (31%), Positives = 69/148 (46%), Gaps = 14/148 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG--- 68
C N G ++C C G+ + A C + C + + C +T CLC
Sbjct: 109 CVNTHGSYKCFCLSGHMLMPD-ATCVNSRTCA---MINCQYSCEDTEEGPQCLCPSSGLR 164
Query: 69 FAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCVCEAGYRPTATRGA--CVDVDEC 124
AP C D+DECA+ + C RCVN+ GS+ C C G+ G C+D++EC
Sbjct: 165 LAPNGRD-CLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC 223
Query: 125 E-EQRVC-RNGRCHNTPGSFRCECLPGF 150
+ C + C NT GSF+C+C G+
Sbjct: 224 TMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 66.5 bits (155), Expect = 2e-10
Identities = 75/254 (29%), Positives = 103/254 (40%), Gaps = 34/254 (13%)
Query: 18 GFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYC 77
G + C G+ S+G V E P C+ G C G C C PG+ T
Sbjct: 44 GTKLACCYGWRRNSKG-----VCEATCEPG-CKFGEC---VGPNKCRCFPGY--TGKTCS 92
Query: 78 ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR--PTATRGACVDVDECEEQRVCRNGRC 135
DV+EC RCVN+ GS++C C +G+ P AT CV+ C C+ C
Sbjct: 93 QDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDAT---CVNSRTCAMIN-CQYS-C 147
Query: 136 HNTPGSFRCEC-LPGFTLSNDGRTCLGLK--LGWGVSC---QACPAQGSELYAVLCPEG- 188
+T +C C G L+ +GR CL + V C + C Y C G
Sbjct: 148 EDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCK-CHIGF 206
Query: 189 ----PSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL-CRDIDEC 242
S DINECT C H +C N + ++C C GY +GL C I E
Sbjct: 207 ELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY--KGNGLRCSAIPEN 264
Query: 243 DMHQSYCAGGQCRN 256
+ + A G ++
Sbjct: 265 SVKEVLRAPGTIKD 278
Score = 63.7 bits (148), Expect = 1e-09
Identities = 71/239 (29%), Positives = 94/239 (39%), Gaps = 43/239 (17%)
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKL 164
C G+R + +G C CE C+ G C G +C C PG+T G+TC
Sbjct: 49 CCYGWRRNS-KGVCEAT--CEPG--CKFGEC---VGPNKCRCFPGYT----GKTCSQDVN 96
Query: 165 GWGVS---CQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR 221
G+ CQ Y C G +N T C + SCE+ E G +
Sbjct: 97 ECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINCQY-SCEDTEEGPQ 155
Query: 222 CIC-DPGYHPDADGL-CRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLC 278
C+C G +G C DIDEC + C +C NT GS+ C C G ELQ
Sbjct: 156 CLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF----ELQ-- 209
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGY 336
YI Y+ DI T + C + C NT G F+C+C+ GY
Sbjct: 210 -------------YISGRYDCIDINEC----TMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 53.6 bits (123), Expect = 1e-06
Identities = 52/167 (31%), Positives = 70/167 (41%), Gaps = 28/167 (16%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAG 259
E T PG C G C + P +C C PGY +D++EC M C +C NT G
Sbjct: 62 EATCEPG-CKFGEC--VGPN-KCRCFPGY--TGKTCSQDVNECGMKPRPCQH-RCVNTHG 114
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGD--IPPTFPTR-------- 309
S+ C C G P+ C + C Y D E G + P+ R
Sbjct: 115 SYKCFCLSGHMLMPD-ATCVNSRTC-AMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDC 172
Query: 310 ---TELASP---CD-NGRCINTHGGFECECELGYVLDATAQR--CLD 347
E AS C N RC+NT G + C+C +G+ L + R C+D
Sbjct: 173 LDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCID 219
Score = 51.2 bits (117), Expect = 7e-06
Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 29/132 (21%)
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
PC + RC+NTHG ++C C G++L A C+++R +C +++ C+ + + +
Sbjct: 104 PCQH-RCVNTHGSYKCFCLSGHMLMPDAT-CVNSR--TC--AMIN--CQYSCEDTEEGPQ 155
Query: 375 CCC-SVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDG 432
C C S GL +G C D+DECA +C CVNT G
Sbjct: 156 CLCPSSGLRLAP-------------------NGRDCLDIDECASGKVICPYNRRCVNTFG 196
Query: 433 SYRCDCPPGLTL 444
SY C C G L
Sbjct: 197 SYYCKCHIGFEL 208
Score = 42.7 bits (96), Expect = 0.003
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 9 NGICKNIDGGFECICKPGYESG--SEGALCRDVDECRDNPRVC-RRGRCRNTAGSYTCLC 65
N C N G + C C G+E S C D++EC + C C NT GS+ C C
Sbjct: 188 NRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKC 247
Query: 66 EPGF 69
+ G+
Sbjct: 248 KQGY 251
Score = 38.7 bits (86), Expect = 0.042
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 401 FAKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
F G TC +DV+EC + C CVNT GSY+C C G
Sbjct: 83 FPGYTGKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSG 123
>AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein
protein.
Length = 554
Score = 92.7 bits (220), Expect = 2e-18
Identities = 74/215 (34%), Positives = 96/215 (44%), Gaps = 24/215 (11%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV-DVDE 123
C G+ + G C E + CK G CV G +C C GY T C DV+E
Sbjct: 49 CCYGWRRNSKGVC----EATCEPGCKFGECV---GPNKCRCFPGY----TGKTCSQDVNE 97
Query: 124 CE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
C + R C++ RC NT GS++C CL G L D TC+ + ++CQ E
Sbjct: 98 CGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCAMINCQYSCEDTEEGPQ 155
Query: 183 VLCPEGPSK--DNGG--ADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPD-ADGL- 235
LCP + NG DI+EC + CP+ C N Y C C G+ G
Sbjct: 156 CLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRY 215
Query: 236 -CRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEG 268
C DI+EC M C+ C NT GSF C C +G
Sbjct: 216 DCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG 250
Score = 85.8 bits (203), Expect = 3e-16
Identities = 55/140 (39%), Positives = 71/140 (50%), Gaps = 11/140 (7%)
Query: 17 GGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAG 75
G +C C PGY G C +DV+EC PR C+ RC NT GSY C C G
Sbjct: 76 GPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA 130
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVC-EAGYRPTATRGACVDVDECEEQRV-CR-N 132
C + CA + C+ C ++E QC+C +G R C+D+DEC +V C N
Sbjct: 131 TCVNSRTCAMIN-CQYS-CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYN 188
Query: 133 GRCHNTPGSFRCECLPGFTL 152
RC NT GS+ C+C GF L
Sbjct: 189 RRCVNTFGSYYCKCHIGFEL 208
Score = 79.0 bits (186), Expect = 3e-14
Identities = 42/122 (34%), Positives = 61/122 (50%), Gaps = 7/122 (5%)
Query: 12 CKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGF 69
C++ + G +C+C G G C D+DEC +C R C NT GSY C C GF
Sbjct: 147 CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF 206
Query: 70 APT--AAGY-CADVDECAADS-MCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
+ Y C D++EC DS C C N++GSF+C C+ GY+ R + + +
Sbjct: 207 ELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSV 266
Query: 125 EE 126
+E
Sbjct: 267 KE 268
Score = 77.8 bits (183), Expect = 7e-14
Identities = 47/148 (31%), Positives = 69/148 (46%), Gaps = 14/148 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG--- 68
C N G ++C C G+ + A C + C + + C +T CLC
Sbjct: 109 CVNTHGSYKCFCLSGHMLMPD-ATCVNSRTCA---MINCQYSCEDTEEGPQCLCPSSGLR 164
Query: 69 FAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCVCEAGYRPTATRGA--CVDVDEC 124
AP C D+DECA+ + C RCVN+ GS+ C C G+ G C+D++EC
Sbjct: 165 LAPNGRD-CLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC 223
Query: 125 E-EQRVC-RNGRCHNTPGSFRCECLPGF 150
+ C + C NT GSF+C+C G+
Sbjct: 224 TMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 66.5 bits (155), Expect = 2e-10
Identities = 75/254 (29%), Positives = 103/254 (40%), Gaps = 34/254 (13%)
Query: 18 GFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYC 77
G + C G+ S+G V E P C+ G C G C C PG+ T
Sbjct: 44 GTKLACCYGWRRNSKG-----VCEATCEPG-CKFGEC---VGPNKCRCFPGY--TGKTCS 92
Query: 78 ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR--PTATRGACVDVDECEEQRVCRNGRC 135
DV+EC RCVN+ GS++C C +G+ P AT CV+ C C+ C
Sbjct: 93 QDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDAT---CVNSRTCAMIN-CQYS-C 147
Query: 136 HNTPGSFRCEC-LPGFTLSNDGRTCLGLK--LGWGVSC---QACPAQGSELYAVLCPEG- 188
+T +C C G L+ +GR CL + V C + C Y C G
Sbjct: 148 EDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCK-CHIGF 206
Query: 189 ----PSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL-CRDIDEC 242
S DINECT C H +C N + ++C C GY +GL C I E
Sbjct: 207 ELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY--KGNGLRCSAIPEN 264
Query: 243 DMHQSYCAGGQCRN 256
+ + A G ++
Sbjct: 265 SVKEVLRAPGTIKD 278
Score = 63.7 bits (148), Expect = 1e-09
Identities = 71/239 (29%), Positives = 94/239 (39%), Gaps = 43/239 (17%)
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKL 164
C G+R + +G C CE C+ G C G +C C PG+T G+TC
Sbjct: 49 CCYGWRRNS-KGVCEAT--CEPG--CKFGEC---VGPNKCRCFPGYT----GKTCSQDVN 96
Query: 165 GWGVS---CQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR 221
G+ CQ Y C G +N T C + SCE+ E G +
Sbjct: 97 ECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINCQY-SCEDTEEGPQ 155
Query: 222 CIC-DPGYHPDADGL-CRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLC 278
C+C G +G C DIDEC + C +C NT GS+ C C G ELQ
Sbjct: 156 CLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF----ELQ-- 209
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGY 336
YI Y+ DI T + C + C NT G F+C+C+ GY
Sbjct: 210 -------------YISGRYDCIDINEC----TMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 53.6 bits (123), Expect = 1e-06
Identities = 52/167 (31%), Positives = 70/167 (41%), Gaps = 28/167 (16%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAG 259
E T PG C G C + P +C C PGY +D++EC M C +C NT G
Sbjct: 62 EATCEPG-CKFGEC--VGPN-KCRCFPGY--TGKTCSQDVNECGMKPRPCQH-RCVNTHG 114
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGD--IPPTFPTR-------- 309
S+ C C G P+ C + C Y D E G + P+ R
Sbjct: 115 SYKCFCLSGHMLMPD-ATCVNSRTC-AMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDC 172
Query: 310 ---TELASP---CD-NGRCINTHGGFECECELGYVLDATAQR--CLD 347
E AS C N RC+NT G + C+C +G+ L + R C+D
Sbjct: 173 LDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCID 219
Score = 51.2 bits (117), Expect = 7e-06
Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 29/132 (21%)
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
PC + RC+NTHG ++C C G++L A C+++R +C +++ C+ + + +
Sbjct: 104 PCQH-RCVNTHGSYKCFCLSGHMLMPDAT-CVNSR--TC--AMIN--CQYSCEDTEEGPQ 155
Query: 375 CCC-SVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDG 432
C C S GL +G C D+DECA +C CVNT G
Sbjct: 156 CLCPSSGLRLAP-------------------NGRDCLDIDECASGKVICPYNRRCVNTFG 196
Query: 433 SYRCDCPPGLTL 444
SY C C G L
Sbjct: 197 SYYCKCHIGFEL 208
Score = 42.7 bits (96), Expect = 0.003
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 9 NGICKNIDGGFECICKPGYESG--SEGALCRDVDECRDNPRVC-RRGRCRNTAGSYTCLC 65
N C N G + C C G+E S C D++EC + C C NT GS+ C C
Sbjct: 188 NRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKC 247
Query: 66 EPGF 69
+ G+
Sbjct: 248 KQGY 251
Score = 38.7 bits (86), Expect = 0.042
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 401 FAKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
F G TC +DV+EC + C CVNT GSY+C C G
Sbjct: 83 FPGYTGKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSG 123
>AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor
repeat containing protein protein.
Length = 553
Score = 92.7 bits (220), Expect = 2e-18
Identities = 74/215 (34%), Positives = 96/215 (44%), Gaps = 24/215 (11%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACV-DVDE 123
C G+ + G C E + CK G CV G +C C GY T C DV+E
Sbjct: 49 CCYGWRRNSKGVC----EATCEPGCKFGECV---GPNKCRCFPGY----TGKTCSQDVNE 97
Query: 124 CE-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGSELYA 182
C + R C++ RC NT GS++C CL G L D TC+ + ++CQ E
Sbjct: 98 CGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA-TCVNSRTCAMINCQYSCEDTEEGPQ 155
Query: 183 VLCPEGPSK--DNGG--ADINECTAVPGACPHGS-CENLEPGYRCICDPGYHPD-ADGL- 235
LCP + NG DI+EC + CP+ C N Y C C G+ G
Sbjct: 156 CLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRY 215
Query: 236 -CRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEG 268
C DI+EC M C+ C NT GSF C C +G
Sbjct: 216 DCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG 250
Score = 85.8 bits (203), Expect = 3e-16
Identities = 55/140 (39%), Positives = 71/140 (50%), Gaps = 11/140 (7%)
Query: 17 GGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAG 75
G +C C PGY G C +DV+EC PR C+ RC NT GSY C C G
Sbjct: 76 GPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSGHMLMPDA 130
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVC-EAGYRPTATRGACVDVDECEEQRV-CR-N 132
C + CA + C+ C ++E QC+C +G R C+D+DEC +V C N
Sbjct: 131 TCVNSRTCAMIN-CQYS-CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYN 188
Query: 133 GRCHNTPGSFRCECLPGFTL 152
RC NT GS+ C+C GF L
Sbjct: 189 RRCVNTFGSYYCKCHIGFEL 208
Score = 79.0 bits (186), Expect = 3e-14
Identities = 42/122 (34%), Positives = 61/122 (50%), Gaps = 7/122 (5%)
Query: 12 CKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPGF 69
C++ + G +C+C G G C D+DEC +C R C NT GSY C C GF
Sbjct: 147 CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF 206
Query: 70 APT--AAGY-CADVDECAADS-MCKG-GRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
+ Y C D++EC DS C C N++GSF+C C+ GY+ R + + +
Sbjct: 207 ELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSV 266
Query: 125 EE 126
+E
Sbjct: 267 KE 268
Score = 77.8 bits (183), Expect = 7e-14
Identities = 47/148 (31%), Positives = 69/148 (46%), Gaps = 14/148 (9%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPG--- 68
C N G ++C C G+ + A C + C + + C +T CLC
Sbjct: 109 CVNTHGSYKCFCLSGHMLMPD-ATCVNSRTCA---MINCQYSCEDTEEGPQCLCPSSGLR 164
Query: 69 FAPTAAGYCADVDECAADSM-CK-GGRCVNSEGSFQCVCEAGYRPTATRGA--CVDVDEC 124
AP C D+DECA+ + C RCVN+ GS+ C C G+ G C+D++EC
Sbjct: 165 LAPNGRD-CLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINEC 223
Query: 125 E-EQRVC-RNGRCHNTPGSFRCECLPGF 150
+ C + C NT GSF+C+C G+
Sbjct: 224 TMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 66.5 bits (155), Expect = 2e-10
Identities = 75/254 (29%), Positives = 103/254 (40%), Gaps = 34/254 (13%)
Query: 18 GFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTAAGYC 77
G + C G+ S+G V E P C+ G C G C C PG+ T
Sbjct: 44 GTKLACCYGWRRNSKG-----VCEATCEPG-CKFGEC---VGPNKCRCFPGY--TGKTCS 92
Query: 78 ADVDECAADSMCKGGRCVNSEGSFQCVCEAGYR--PTATRGACVDVDECEEQRVCRNGRC 135
DV+EC RCVN+ GS++C C +G+ P AT CV+ C C+ C
Sbjct: 93 QDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDAT---CVNSRTCAMIN-CQYS-C 147
Query: 136 HNTPGSFRCEC-LPGFTLSNDGRTCLGLK--LGWGVSC---QACPAQGSELYAVLCPEG- 188
+T +C C G L+ +GR CL + V C + C Y C G
Sbjct: 148 EDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCK-CHIGF 206
Query: 189 ----PSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGYHPDADGL-CRDIDEC 242
S DINECT C H +C N + ++C C GY +GL C I E
Sbjct: 207 ELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGY--KGNGLRCSAIPEN 264
Query: 243 DMHQSYCAGGQCRN 256
+ + A G ++
Sbjct: 265 SVKEVLRAPGTIKD 278
Score = 63.7 bits (148), Expect = 1e-09
Identities = 71/239 (29%), Positives = 94/239 (39%), Gaps = 43/239 (17%)
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHNTPGSFRCECLPGFTLSNDGRTCLGLKL 164
C G+R + +G C CE C+ G C G +C C PG+T G+TC
Sbjct: 49 CCYGWRRNS-KGVCEAT--CEPG--CKFGEC---VGPNKCRCFPGYT----GKTCSQDVN 96
Query: 165 GWGVS---CQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYR 221
G+ CQ Y C G +N T C + SCE+ E G +
Sbjct: 97 ECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINCQY-SCEDTEEGPQ 155
Query: 222 CIC-DPGYHPDADGL-CRDIDECDMHQSYCA-GGQCRNTAGSFTCVCPEGTRHEPELQLC 278
C+C G +G C DIDEC + C +C NT GS+ C C G ELQ
Sbjct: 156 CLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGF----ELQ-- 209
Query: 279 RDIDECEGETETHYIESDYERGDIPPTFPTRTELASPCDN-GRCINTHGGFECECELGY 336
YI Y+ DI T + C + C NT G F+C+C+ GY
Sbjct: 210 -------------YISGRYDCIDINEC----TMDSHTCSHHANCFNTQGSFKCKCKQGY 251
Score = 53.6 bits (123), Expect = 1e-06
Identities = 52/167 (31%), Positives = 70/167 (41%), Gaps = 28/167 (16%)
Query: 200 ECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAG 259
E T PG C G C + P +C C PGY +D++EC M C +C NT G
Sbjct: 62 EATCEPG-CKFGEC--VGPN-KCRCFPGY--TGKTCSQDVNECGMKPRPCQH-RCVNTHG 114
Query: 260 SFTCVCPEGTRHEPELQLCRDIDECEGETETHYIESDYERGD--IPPTFPTR-------- 309
S+ C C G P+ C + C Y D E G + P+ R
Sbjct: 115 SYKCFCLSGHMLMPD-ATCVNSRTC-AMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDC 172
Query: 310 ---TELASP---CD-NGRCINTHGGFECECELGYVLDATAQR--CLD 347
E AS C N RC+NT G + C+C +G+ L + R C+D
Sbjct: 173 LDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCID 219
Score = 51.2 bits (117), Expect = 7e-06
Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 29/132 (21%)
Query: 315 PCDNGRCINTHGGFECECELGYVLDATAQRCLDNRRGSCWRRVVDGQCEAAAPELLLRQE 374
PC + RC+NTHG ++C C G++L A C+++R +C +++ C+ + + +
Sbjct: 104 PCQH-RCVNTHGSYKCFCLSGHMLMPDAT-CVNSR--TC--AMIN--CQYSCEDTEEGPQ 155
Query: 375 CCC-SVGLAWGSXXXXXXXXXXXXXKGFAKLDGATCRDVDECALSAELCA-GGTCVNTDG 432
C C S GL +G C D+DECA +C CVNT G
Sbjct: 156 CLCPSSGLRLAP-------------------NGRDCLDIDECASGKVICPYNRRCVNTFG 196
Query: 433 SYRCDCPPGLTL 444
SY C C G L
Sbjct: 197 SYYCKCHIGFEL 208
Score = 42.7 bits (96), Expect = 0.003
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 9 NGICKNIDGGFECICKPGYESG--SEGALCRDVDECRDNPRVC-RRGRCRNTAGSYTCLC 65
N C N G + C C G+E S C D++EC + C C NT GS+ C C
Sbjct: 188 NRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKC 247
Query: 66 EPGF 69
+ G+
Sbjct: 248 KQGY 251
Score = 38.7 bits (86), Expect = 0.042
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 401 FAKLDGATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPG 441
F G TC +DV+EC + C CVNT GSY+C C G
Sbjct: 83 FPGYTGKTCSQDVNECGMKPRPCQH-RCVNTHGSYKCFCLSG 123
>AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein.
Length = 509
Score = 92.3 bits (219), Expect = 3e-18
Identities = 72/222 (32%), Positives = 99/222 (44%), Gaps = 38/222 (17%)
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
C G+A + G C V CK G C+ G +C C GY A + D++EC
Sbjct: 44 CCWGWARQSWGQCQPV----CQPRCKHGECI---GPNKCKCHPGY---AGKTCNQDLNEC 93
Query: 125 E-EQRVCRNGRCHNTPGSFRCECLPGFTLSNDGR-----TCLGLKLGWG-------VSCQ 171
+ R C++ RC NT GS++C CL G+ L DG TC +G + CQ
Sbjct: 94 GLKPRPCKH-RCMNTYGSYKCYCLNGYMLMPDGSCSSALTCSMANCQYGCDVVKGQIRCQ 152
Query: 172 ACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPH-GSCENLEPGYRCICDPGY-- 228
CP+ G L P+G + D++EC +CP C N Y C C G+
Sbjct: 153 -CPSPGLH----LAPDGRT----CVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDL 203
Query: 229 -HPDADGLCRDIDECDMHQSYCAG-GQCRNTAGSFTCVCPEG 268
+ C DIDEC + Q C+ +C N GS+ C C EG
Sbjct: 204 MYIGGKYQCHDIDECSLGQYQCSSFARCYNVRGSYKCKCKEG 245
Score = 86.6 bits (205), Expect = 2e-16
Identities = 58/150 (38%), Positives = 75/150 (50%), Gaps = 14/150 (9%)
Query: 7 CTNGICKNIDGGFECICKPGYESGSEGALC-RDVDECRDNPRVCRRGRCRNTAGSYTCLC 65
C +G C G +C C PGY G C +D++EC PR C+ RC NT GSY C C
Sbjct: 64 CKHGECI---GPNKCKCHPGYA----GKTCNQDLNECGLKPRPCKH-RCMNTYGSYKCYC 115
Query: 66 EPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRG-ACVDVDEC 124
G+ G C+ C+ + C+ G C +G +C C + A G CVDVDEC
Sbjct: 116 LNGYMLMPDGSCSSALTCSM-ANCQYG-CDVVKGQIRCQCPSPGLHLAPDGRTCVDVDEC 173
Query: 125 EEQRV-C-RNGRCHNTPGSFRCECLPGFTL 152
R C R +C NT GS+ C+C GF L
Sbjct: 174 ATGRASCPRFRQCVNTFGSYICKCHKGFDL 203
Score = 83.0 bits (196), Expect = 2e-15
Identities = 56/157 (35%), Positives = 74/157 (47%), Gaps = 14/157 (8%)
Query: 12 CKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLC-EPGFA 70
C N G ++C C GY +G+ C C + C+ G C G C C PG
Sbjct: 104 CMNTYGSYKCYCLNGYMLMPDGS-CSSALTC--SMANCQYG-CDVVKGQIRCQCPSPGLH 159
Query: 71 PTAAGY-CADVDECAAD-SMCKGGR-CVNSEGSFQCVCEAGYRPTATRGA--CVDVDECE 125
G C DVDECA + C R CVN+ GS+ C C G+ G C D+DEC
Sbjct: 160 LAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECS 219
Query: 126 -EQRVCRN-GRCHNTPGSFRCECLPGFTLSNDGRTCL 160
Q C + RC+N GS++C+C G+ DG TC+
Sbjct: 220 LGQYQCSSFARCYNVRGSYKCKCKEGY--QGDGLTCV 254
Score = 78.6 bits (185), Expect = 4e-14
Identities = 75/235 (31%), Positives = 101/235 (42%), Gaps = 32/235 (13%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGF 69
G+C+ G +C G+ S G C+ V C+ PR C+ G C G C C PG+
Sbjct: 34 GLCR-YGGRIDCCW--GWARQSWGQ-CQPV--CQ--PR-CKHGEC---IGPNKCKCHPGY 81
Query: 70 APTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQRV 129
A D++EC RC+N+ GS++C C GY G+C C
Sbjct: 82 AGKTCNQ--DLNECGLKPRPCKHRCMNTYGSYKCYCLNGYM-LMPDGSCSSALTCSMAN- 137
Query: 130 CRNGRCHNTPGSFRCEC-LPGFTLSNDGRTCLGL-KLGWG-VSC----QACPAQGSELYA 182
C+ G C G RC+C PG L+ DGRTC+ + + G SC Q GS Y
Sbjct: 138 CQYG-CDVVKGQIRCQCPSPGLHLAPDGRTCVDVDECATGRASCPRFRQCVNTFGS--YI 194
Query: 183 VLCPEG-PSKDNGGA----DINECTAVPGACPH-GSCENLEPGYRCICDPGYHPD 231
C +G GG DI+EC+ C C N+ Y+C C GY D
Sbjct: 195 CKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCYNVRGSYKCKCKEGYQGD 249
Score = 78.6 bits (185), Expect = 4e-14
Identities = 44/111 (39%), Positives = 52/111 (46%), Gaps = 8/111 (7%)
Query: 7 CTNGICKNIDGGFECIC-KPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCL 64
C G C + G C C PG +G C DVDEC C R R C NT GSY C
Sbjct: 138 CQYG-CDVVKGQIRCQCPSPGLHLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICK 196
Query: 65 CEPGFAPTAAG---YCADVDECAADS-MCKG-GRCVNSEGSFQCVCEAGYR 110
C GF G C D+DEC+ C RC N GS++C C+ GY+
Sbjct: 197 CHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCYNVRGSYKCKCKEGYQ 247
Score = 60.1 bits (139), Expect = 2e-08
Identities = 35/101 (34%), Positives = 42/101 (41%), Gaps = 5/101 (4%)
Query: 185 CPEGPSKDNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDM 244
C G + D+NEC P C H C N Y+C C GY DG C C M
Sbjct: 77 CHPGYAGKTCNQDLNECGLKPRPCKH-RCMNTYGSYKCYCLNGYMLMPDGSCSSALTCSM 135
Query: 245 HQSYCAGGQCRNTAGSFTCVCPEGTRH-EPELQLCRDIDEC 284
+ C G C G C CP H P+ + C D+DEC
Sbjct: 136 --ANCQYG-CDVVKGQIRCQCPSPGLHLAPDGRTCVDVDEC 173
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/148 (31%), Positives = 64/148 (43%), Gaps = 22/148 (14%)
Query: 315 PCDNGRCINTHGGFECECELGYVL--DATAQRCLDNRRGSCWRR--VVDGQ--CEAAAPE 368
PC + RC+NT+G ++C C GY+L D + L +C VV GQ C+ +P
Sbjct: 99 PCKH-RCMNTYGSYKCYCLNGYMLMPDGSCSSALTCSMANCQYGCDVVKGQIRCQCPSPG 157
Query: 369 LLLRQE---CC----CSVGLA----WGSXXXXXXXXXXXXXKGF--AKLDGA-TCRDVDE 414
L L + C C+ G A + KGF + G C D+DE
Sbjct: 158 LHLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDE 217
Query: 415 CALSAELCAG-GTCVNTDGSYRCDCPPG 441
C+L C+ C N GSY+C C G
Sbjct: 218 CSLGQYQCSSFARCYNVRGSYKCKCKEG 245
Score = 46.0 bits (104), Expect = 3e-04
Identities = 45/150 (30%), Positives = 61/150 (40%), Gaps = 29/150 (19%)
Query: 208 CPHGSCENLEPGYRCICDPGYHPDADGLC-RDIDECDMHQSYCAGGQCRNTAGSFTCVCP 266
C HG C + P +C C PGY A C +D++EC + C +C NT GS+ C C
Sbjct: 64 CKHGEC--IGPN-KCKCHPGY---AGKTCNQDLNECGLKPRPCKH-RCMNTYGSYKCYCL 116
Query: 267 EGTRHEPELQLCRDIDECEGETETHYIESDYERGDIPPTFPT---------RTEL-ASPC 316
G P+ C C Y D +G I P+ RT + C
Sbjct: 117 NGYMLMPD-GSCSSALTC-SMANCQY-GCDVVKGQIRCQCPSPGLHLAPDGRTCVDVDEC 173
Query: 317 DNGR--------CINTHGGFECECELGYVL 338
GR C+NT G + C+C G+ L
Sbjct: 174 ATGRASCPRFRQCVNTFGSYICKCHKGFDL 203
Score = 37.1 bits (82), Expect = 0.13
Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 406 GATC-RDVDECALSAELCAGGTCVNTDGSYRCDCPPGLTLDSTGT 449
G TC +D++EC L C C+NT GSY+C C G L G+
Sbjct: 83 GKTCNQDLNECGLKPRPCKH-RCMNTYGSYKCYCLNGYMLMPDGS 126
>BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein.
Length = 763
Score = 91.9 bits (218), Expect = 4e-18
Identities = 66/212 (31%), Positives = 91/212 (42%), Gaps = 22/212 (10%)
Query: 35 LCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA--AGYCADVDECAAD-SMCKG 91
+CR + C + P+ C+N TC C+ G+ + YC D+DECAA C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 92 GR-CVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVC-RNGRCHNTPGSFRCECLP 148
CVN G ++C C GY +C + DEC Q C N C NT C C P
Sbjct: 448 NTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 149 GFTLSNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVP 205
G+ +G C +G +C A P + +CP G + + DI+EC
Sbjct: 507 GYV--GNGTICRAFCEEGCRYGGTCVA-PNK------CVCPSGFTGSHCEKDIDECALRT 557
Query: 206 GACPHGS-CENLEPGYRCICDPGYHPDADGLC 236
C + S C NL G+ C+C G P G C
Sbjct: 558 HTCWNDSACINLAGGFDCLCPSG--PSCSGDC 587
Score = 77.4 bits (182), Expect = 1e-13
Identities = 58/198 (29%), Positives = 86/198 (43%), Gaps = 16/198 (8%)
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDECE-EQRVCR-N 132
+CA+ +C +S CK N++ + C C++GY A C D+DEC + C N
Sbjct: 394 FCAEGPKCGENSECKNW---NTKAT--CECKSGYISVQGDSAYCEDIDECAAKMHYCHAN 448
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQACPAQGSELYAVLCPEGPSK 191
C N PG +RC+C+PG+ +D + G G +C + + C P
Sbjct: 449 TVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
Query: 192 DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC-A 250
G I G G+C + P +C+C G+ +DIDEC + C
Sbjct: 509 VGNGT-ICRAFCEEGCRYGGTC--VAPN-KCVCPSGF--TGSHCEKDIDECALRTHTCWN 562
Query: 251 GGQCRNTAGSFTCVCPEG 268
C N AG F C+CP G
Sbjct: 563 DSACINLAGGFDCLCPSG 580
Score = 77.4 bits (182), Expect = 1e-13
Identities = 79/250 (31%), Positives = 95/250 (38%), Gaps = 28/250 (11%)
Query: 9 NGICKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
N CKN + C CK GY S + A C D+DEC C C N G Y C C
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCV 463
Query: 67 PGFAPTAAGYCADVDEC-AADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
PG+ C + DEC + C + C N+ C C+ GY T C C
Sbjct: 464 PGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT--ICRAF--C 519
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTC-LGLKLGWGVSCQACPAQGSEL 180
EE CR G P +C C GFT S+ D C L W S A G
Sbjct: 520 EEG--CRYGGTCVAPN--KCVCPSGFTGSHCEKDIDECALRTHTCWNDSACINLAGG--- 572
Query: 181 YAVLCPEGPS-----KDNGGADIN--ECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ LCP GPS GG N T C SC++ + R +P AD
Sbjct: 573 FDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSAD 632
Query: 234 GLCRDIDECD 243
C ECD
Sbjct: 633 LFC--CPECD 640
Score = 50.8 bits (116), Expect = 1e-05
Identities = 21/38 (55%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPG 441
D A C D+DECA C T CVN G YRCDC PG
Sbjct: 428 DSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPG 465
Score = 42.3 bits (95), Expect = 0.003
Identities = 52/222 (23%), Positives = 75/222 (33%), Gaps = 44/222 (19%)
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECEGETETHYI 293
+CR + C +C+N TC C G + + C DIDEC + HY
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKM--HYC 445
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYV----LDATAQRCLDNR 349
+ N C+N G + C+C GY+ T +
Sbjct: 446 HA----------------------NTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSG 483
Query: 350 RGSC-----WRRVVDGQCEAAAPELLLRQECC---CSVGLAWGSXXXXXXXXXXXXXKGF 401
+ +C V G P + C C G +G GF
Sbjct: 484 QHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPS--GF 541
Query: 402 AKLDGATC-RDVDECALSAELCAGGT-CVNTDGSYRCDCPPG 441
G+ C +D+DECAL C + C+N G + C CP G
Sbjct: 542 T---GSHCEKDIDECALRTHTCWNDSACINLAGGFDCLCPSG 580
Score = 35.5 bits (78), Expect = 0.39
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDST 447
G+ ++D +C + DEC C C NT + C C PG + T
Sbjct: 465 GYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 513
>BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein.
Length = 763
Score = 91.9 bits (218), Expect = 4e-18
Identities = 66/212 (31%), Positives = 91/212 (42%), Gaps = 22/212 (10%)
Query: 35 LCRDVDECRDNPRVCRRGRCRNTAGSYTCLCEPGFAPTA--AGYCADVDECAAD-SMCKG 91
+CR + C + P+ C+N TC C+ G+ + YC D+DECAA C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 92 GR-CVNSEGSFQCVCEAGYRPTATRGACVDVDEC-EEQRVC-RNGRCHNTPGSFRCECLP 148
CVN G ++C C GY +C + DEC Q C N C NT C C P
Sbjct: 448 NTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 149 GFTLSNDGRTCLGL---KLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVP 205
G+ +G C +G +C A P + +CP G + + DI+EC
Sbjct: 507 GYV--GNGTICRAFCEEGCRYGGTCVA-PNK------CVCPSGFTGSHCEKDIDECALRT 557
Query: 206 GACPHGS-CENLEPGYRCICDPGYHPDADGLC 236
C + S C NL G+ C+C G P G C
Sbjct: 558 HTCWNDSACINLAGGFDCLCPSG--PSCSGDC 587
Score = 77.4 bits (182), Expect = 1e-13
Identities = 58/198 (29%), Positives = 86/198 (43%), Gaps = 16/198 (8%)
Query: 76 YCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGA-CVDVDECE-EQRVCR-N 132
+CA+ +C +S CK N++ + C C++GY A C D+DEC + C N
Sbjct: 394 FCAEGPKCGENSECKNW---NTKAT--CECKSGYISVQGDSAYCEDIDECAAKMHYCHAN 448
Query: 133 GRCHNTPGSFRCECLPGFTLSNDGRTCLGLKLGWGV-SCQACPAQGSELYAVLCPEGPSK 191
C N PG +RC+C+PG+ +D + G G +C + + C P
Sbjct: 449 TVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
Query: 192 DNGGADINECTAVPGACPHGSCENLEPGYRCICDPGYHPDADGLCRDIDECDMHQSYC-A 250
G I G G+C + P +C+C G+ +DIDEC + C
Sbjct: 509 VGNGT-ICRAFCEEGCRYGGTC--VAPN-KCVCPSGF--TGSHCEKDIDECALRTHTCWN 562
Query: 251 GGQCRNTAGSFTCVCPEG 268
C N AG F C+CP G
Sbjct: 563 DSACINLAGGFDCLCPSG 580
Score = 77.4 bits (182), Expect = 1e-13
Identities = 79/250 (31%), Positives = 95/250 (38%), Gaps = 28/250 (11%)
Query: 9 NGICKNIDGGFECICKPGYES-GSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCE 66
N CKN + C CK GY S + A C D+DEC C C N G Y C C
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCV 463
Query: 67 PGFAPTAAGYCADVDEC-AADSMC-KGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDEC 124
PG+ C + DEC + C + C N+ C C+ GY T C C
Sbjct: 464 PGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT--ICRAF--C 519
Query: 125 EEQRVCRNGRCHNTPGSFRCECLPGFTLSN---DGRTC-LGLKLGWGVSCQACPAQGSEL 180
EE CR G P +C C GFT S+ D C L W S A G
Sbjct: 520 EEG--CRYGGTCVAPN--KCVCPSGFTGSHCEKDIDECALRTHTCWNDSACINLAGG--- 572
Query: 181 YAVLCPEGPS-----KDNGGADIN--ECTAVPGACPHGSCENLEPGYRCICDPGYHPDAD 233
+ LCP GPS GG N T C SC++ + R +P AD
Sbjct: 573 FDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSAD 632
Query: 234 GLCRDIDECD 243
C ECD
Sbjct: 633 LFC--CPECD 640
Score = 50.8 bits (116), Expect = 1e-05
Identities = 21/38 (55%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 405 DGATCRDVDECALSAELCAGGT-CVNTDGSYRCDCPPG 441
D A C D+DECA C T CVN G YRCDC PG
Sbjct: 428 DSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPG 465
Score = 42.3 bits (95), Expect = 0.003
Identities = 52/222 (23%), Positives = 75/222 (33%), Gaps = 44/222 (19%)
Query: 235 LCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG-TRHEPELQLCRDIDECEGETETHYI 293
+CR + C +C+N TC C G + + C DIDEC + HY
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKM--HYC 445
Query: 294 ESDYERGDIPPTFPTRTELASPCDNGRCINTHGGFECECELGYV----LDATAQRCLDNR 349
+ N C+N G + C+C GY+ T +
Sbjct: 446 HA----------------------NTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSG 483
Query: 350 RGSC-----WRRVVDGQCEAAAPELLLRQECC---CSVGLAWGSXXXXXXXXXXXXXKGF 401
+ +C V G P + C C G +G GF
Sbjct: 484 QHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPS--GF 541
Query: 402 AKLDGATC-RDVDECALSAELCAGGT-CVNTDGSYRCDCPPG 441
G+ C +D+DECAL C + C+N G + C CP G
Sbjct: 542 T---GSHCEKDIDECALRTHTCWNDSACINLAGGFDCLCPSG 580
Score = 35.5 bits (78), Expect = 0.39
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 400 GFAKLDGATCRDVDECALSAELC-AGGTCVNTDGSYRCDCPPGLTLDST 447
G+ ++D +C + DEC C C NT + C C PG + T
Sbjct: 465 GYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGT 513
>BC133013-1|AAI33014.1| 594|Homo sapiens EGF-like-domain, multiple
11 protein.
Length = 594
Score = 91.5 bits (217), Expect = 6e-18
Identities = 68/229 (29%), Positives = 98/229 (42%), Gaps = 28/229 (12%)
Query: 52 GRCRNTAGS--YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNS-----EGSFQCV 104
G+C + A S Y+C C+P P + YC ++D C+ G C+N E +++CV
Sbjct: 187 GKCLSEAWSKTYSCHCQP---PFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECV 243
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHN-TPGSFRCECLPGFT---LSNDGRTCL 160
C P T C ++ + VC +G C N T SF CEC F+ + C+
Sbjct: 244 CH----PPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCV 299
Query: 161 GLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPG 219
L L W CP S Y CP+G S NG D++E + VP C +G+ C +
Sbjct: 300 SL-LFWKRGI--CP-NSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKISND 353
Query: 220 YRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
CIC P + D LC+ I C+ + C C G
Sbjct: 354 VMCICSPIF---TDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISG 399
Score = 50.4 bits (115), Expect = 1e-05
Identities = 38/151 (25%), Positives = 55/151 (36%), Gaps = 12/151 (7%)
Query: 6 MCTNGICKNI-DGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
+C +G C NI F C C + G C + + +RG C N++ +YT
Sbjct: 264 VCFHGNCSNITSNSFICECDEQFS----GPFCEVSAKPCVSLLFWKRGICPNSSSAYTYE 319
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD-E 123
C G + DV E + G C+ C+C P T C +
Sbjct: 320 CPKGSSSQNGE--TDVSEFSLVPCQNGTDCIKISNDVMCICS----PIFTDLLCKSIQTS 373
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSN 154
CE + N C + C C+ GFT N
Sbjct: 374 CESFPLRNNATCKKCEKDYPCSCISGFTEKN 404
Score = 45.6 bits (103), Expect = 4e-04
Identities = 39/146 (26%), Positives = 54/146 (36%), Gaps = 15/146 (10%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
GIC N + C G S G DV E P C+ G C + C+C P
Sbjct: 307 GICPNSSSAYTYECPKG-SSSQNGET--DVSEFSLVP--CQNGTDCIKISNDVMCICSPI 361
Query: 69 FAPTAAGYCADVD-ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
F C + C + + C E + C C +G+ A +D C+
Sbjct: 362 FTDLL---CKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKA---IDHCKLL 415
Query: 128 RV-CRNGR-CHNTPGSFRCECLPGFT 151
+ C N C N G F+ C+PG T
Sbjct: 416 SINCLNEEWCFNIIGRFKYVCIPGCT 441
Score = 35.9 bits (79), Expect = 0.29
Identities = 36/151 (23%), Positives = 61/151 (40%), Gaps = 25/151 (16%)
Query: 132 NGRCHNTPGS--FRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS----------E 179
+G+C + S + C C P F+ G+ C L S + C GS +
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFS----GKYCQELD---ACSFKPCKNNGSCINKRENWDEQ 238
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRD 238
Y +C + N I +C P C HG+C N+ + C CD + + C
Sbjct: 239 AYECVCHPPFTGKNCSEIIGQCQ--PHVCFHGNCSNITSNSFICECDEQF---SGPFCEV 293
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGT 269
+ + + G C N++ ++T CP+G+
Sbjct: 294 SAKPCVSLLFWKRGICPNSSSAYTYECPKGS 324
>BC133011-1|AAI33012.1| 594|Homo sapiens EGF-like-domain, multiple
11 protein.
Length = 594
Score = 91.5 bits (217), Expect = 6e-18
Identities = 68/229 (29%), Positives = 98/229 (42%), Gaps = 28/229 (12%)
Query: 52 GRCRNTAGS--YTCLCEPGFAPTAAGYCADVDECAADSMCKGGRCVNS-----EGSFQCV 104
G+C + A S Y+C C+P P + YC ++D C+ G C+N E +++CV
Sbjct: 187 GKCLSEAWSKTYSCHCQP---PFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECV 243
Query: 105 CEAGYRPTATRGACVDVDECEEQRVCRNGRCHN-TPGSFRCECLPGFT---LSNDGRTCL 160
C P T C ++ + VC +G C N T SF CEC F+ + C+
Sbjct: 244 CH----PPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCV 299
Query: 161 GLKLGWGVSCQACPAQGSELYAVLCPEGPSKDNGGADINECTAVPGACPHGS-CENLEPG 219
L L W CP S Y CP+G S NG D++E + VP C +G+ C +
Sbjct: 300 SL-LFWKRGI--CP-NSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKISND 353
Query: 220 YRCICDPGYHPDADGLCRDIDECDMHQSYCAGGQCRNTAGSFTCVCPEG 268
CIC P + D LC+ I C+ + C C G
Sbjct: 354 VMCICSPIF---TDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISG 399
Score = 50.4 bits (115), Expect = 1e-05
Identities = 38/151 (25%), Positives = 55/151 (36%), Gaps = 12/151 (7%)
Query: 6 MCTNGICKNI-DGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGRCRNTAGSYTCL 64
+C +G C NI F C C + G C + + +RG C N++ +YT
Sbjct: 264 VCFHGNCSNITSNSFICECDEQFS----GPFCEVSAKPCVSLLFWKRGICPNSSSAYTYE 319
Query: 65 CEPGFAPTAAGYCADVDECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVD-E 123
C G + DV E + G C+ C+C P T C +
Sbjct: 320 CPKGSSSQNGE--TDVSEFSLVPCQNGTDCIKISNDVMCICS----PIFTDLLCKSIQTS 373
Query: 124 CEEQRVCRNGRCHNTPGSFRCECLPGFTLSN 154
CE + N C + C C+ GFT N
Sbjct: 374 CESFPLRNNATCKKCEKDYPCSCISGFTEKN 404
Score = 45.6 bits (103), Expect = 4e-04
Identities = 39/146 (26%), Positives = 54/146 (36%), Gaps = 15/146 (10%)
Query: 10 GICKNIDGGFECICKPGYESGSEGALCRDVDECRDNPRVCRRGR-CRNTAGSYTCLCEPG 68
GIC N + C G S G DV E P C+ G C + C+C P
Sbjct: 307 GICPNSSSAYTYECPKG-SSSQNGET--DVSEFSLVP--CQNGTDCIKISNDVMCICSPI 361
Query: 69 FAPTAAGYCADVD-ECAADSMCKGGRCVNSEGSFQCVCEAGYRPTATRGACVDVDECEEQ 127
F C + C + + C E + C C +G+ A +D C+
Sbjct: 362 FTDLL---CKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKA---IDHCKLL 415
Query: 128 RV-CRNGR-CHNTPGSFRCECLPGFT 151
+ C N C N G F+ C+PG T
Sbjct: 416 SINCLNEEWCFNIIGRFKYVCIPGCT 441
Score = 35.9 bits (79), Expect = 0.29
Identities = 36/151 (23%), Positives = 61/151 (40%), Gaps = 25/151 (16%)
Query: 132 NGRCHNTPGS--FRCECLPGFTLSNDGRTCLGLKLGWGVSCQACPAQGS----------E 179
+G+C + S + C C P F+ G+ C L S + C GS +
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFS----GKYCQELD---ACSFKPCKNNGSCINKRENWDEQ 238
Query: 180 LYAVLCPEGPSKDNGGADINECTAVPGACPHGSCENLEPG-YRCICDPGYHPDADGLCRD 238
Y +C + N I +C P C HG+C N+ + C CD + + C
Sbjct: 239 AYECVCHPPFTGKNCSEIIGQCQ--PHVCFHGNCSNITSNSFICECDEQF---SGPFCEV 293
Query: 239 IDECDMHQSYCAGGQCRNTAGSFTCVCPEGT 269
+ + + G C N++ ++T CP+G+
Sbjct: 294 SAKPCVSLLFWKRGICPNSSSAYTYECPKGS 324
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.140 0.485
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 84,269,336
Number of Sequences: 224733
Number of extensions: 4250803
Number of successful extensions: 41030
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 637
Number of HSP's successfully gapped in prelim test: 448
Number of HSP's that attempted gapping in prelim test: 8714
Number of HSP's gapped (non-prelim): 13783
length of query: 453
length of database: 73,234,838
effective HSP length: 92
effective length of query: 361
effective length of database: 52,559,402
effective search space: 18973944122
effective search space used: 18973944122
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
- SilkBase 1999-2023 -