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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000204-TA|BGIBMGA000204-PA|IPR003822|Paired amphipathic
helix, IPR013194|Histone deacetylase interacting
         (1039 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AY706204-1|AAU01916.1| 1162|Homo sapiens SIN3B long isoform prot...   407   e-112
AK027559-1|BAB55197.1| 1026|Homo sapiens protein ( Homo sapiens ...   382   e-105
AF418569-1|AAP97288.1| 1273|Homo sapiens MSIN3A protein.              382   e-105
AK096477-1|BAC04801.1|  810|Homo sapiens protein ( Homo sapiens ...   360   2e-98
AB014600-1|BAA31675.2| 1137|Homo sapiens KIAA0700 protein protein.    324   1e-87
AY044430-1|AAK95854.1|  621|Homo sapiens transcriptional co-repr...   208   1e-52
AK074903-1|BAC11280.1|  573|Homo sapiens protein ( Homo sapiens ...   155   8e-37
BC110821-1|AAI10822.1|  353|Homo sapiens SIN3B protein protein.       146   5e-34
BC063531-1|AAH63531.1|  353|Homo sapiens SIN3B protein protein.       146   5e-34
BC025026-1|AAH25026.1|  352|Homo sapiens SIN3B protein protein.       146   5e-34
BC018973-1|AAH18973.1|  417|Homo sapiens SIN3A protein protein.        38   0.19 
AL117513-1|CAB55972.1|  361|Homo sapiens hypothetical protein pr...    38   0.19 
BC005113-1|AAH05113.1|  420|Homo sapiens SIN3B protein protein.        35   1.7  
AF086762-1|AAF28400.1| 1111|Homo sapiens C11orf9 protein.              35   1.7  
AB023171-1|BAA76798.2| 1183|Homo sapiens KIAA0954 protein protein.     35   1.7  
BC117557-1|AAI17558.1| 1098|Homo sapiens GON4L protein protein.        33   5.3  
BC064933-1|AAH64933.1|  719|Homo sapiens GON4L protein protein.        33   5.3  
AY335491-1|AAR01261.1| 2241|Homo sapiens GON4L isoform C protein.      33   5.3  
AY335490-1|AAR01260.1| 2241|Homo sapiens GON4L isoform A protein.      33   5.3  
AL162734-1|CAH71640.1| 1078|Homo sapiens novel protein protein.        33   5.3  
AL139128-1|CAH69942.1| 1078|Homo sapiens novel protein protein.        33   5.3  
AK000210-1|BAA91011.1|  697|Homo sapiens protein ( Homo sapiens ...    33   5.3  
AB195687-1|BAF51556.1| 2240|Homo sapiens YY1AP-related protein1 ...    33   5.3  
AB046826-1|BAB13432.1| 1095|Homo sapiens KIAA1606 protein protein.     33   5.3  
L06845-1|AAA73901.1|  595|Homo sapiens cysteinyl-tRNA synthetase...    33   7.0  
BT009913-1|AAP88915.1|  748|Homo sapiens cysteinyl-tRNA syntheta...    33   7.0  
BC002880-1|AAH02880.1|  748|Homo sapiens cysteinyl-tRNA syntheta...    33   7.0  
AK222614-1|BAD96334.1|  726|Homo sapiens cysteine-tRNA ligase is...    33   7.0  
AF288207-1|AAG00579.1|  726|Homo sapiens cysteinyl-tRNA syntheta...    33   7.0  
AF288206-1|AAG00578.1|  748|Homo sapiens cytoplasmic cysteinyl-t...    33   7.0  
AB208814-1|BAD92051.1|  281|Homo sapiens cysteine-tRNA ligase is...    33   7.0  

>AY706204-1|AAU01916.1| 1162|Homo sapiens SIN3B long isoform
           protein.
          Length = 1162

 Score =  407 bits (1002), Expect = e-112
 Identities = 238/546 (43%), Positives = 309/546 (56%), Gaps = 32/546 (5%)

Query: 206 EFNHAIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKL 265
           EFN+AI YVNKIK+RF   P+ Y+ FLEILH YQ+   + +    +  +E+EV+++VA L
Sbjct: 161 EFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANL 220

Query: 266 FEHQEDLLAEFGQFLPDAKA--VTKPEPAHEHHPMTFPTXXXXXXXXXXXXXXCLSGATV 323
           F  QEDLL+EFGQFLP+AK    T   P   H                      L   + 
Sbjct: 221 FRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSA 280

Query: 324 -----------RDVSYSEAAKLATIHDYSFFERARKALRSQQVYDNFLRCLLLFTNEIIS 372
                      +D+S +   K  T+ ++SFF++ R+ L+SQ+VY+NFLRC+ LF  E++S
Sbjct: 281 PAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVS 340

Query: 373 SSELLSVTSPFLCRHPELQRWLHDFVGXXXXXXXXXXXXXXGYPWTNPIPVEPRPRY-ES 431
            SELL + SPFL + PEL      F+G              G   +  I      R   S
Sbjct: 341 GSELLQLVSPFLGKFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSS 400

Query: 432 VGALGAQMRNDRPQGDMAMDIDLSTCKRLGTSYCALPREAAARKCSGRTPLCKEVLNDTW 491
             AL    +  +  G  A+  +L     L  S+      +  +           VLNDTW
Sbjct: 401 YRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTW 460

Query: 492 VSFPTWSEDSTFVTSRKTQYEEYIYRCEDERFELDVVIETNAATIRVLEGVQKKLSRMSG 551
           VSFP+WSEDSTFV+S+KT YEE ++RCEDERFELDVV+ETN ATIRVLE VQKKLSRM+ 
Sbjct: 461 VSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAP 520

Query: 552 EDAARYRLDDCLGGHSPTVHQRALRRIYGDKVAVDIIAGXXXXXXXXXXXXXXXXXXKEE 611
           ED  ++RLDD LGG S  + +RA+ RIYGDK A +II                    KEE
Sbjct: 521 EDQEKFRLDDSLGGTSEVIQRRAIYRIYGDK-APEIIESLKKNPVTAVPVVLKRLKAKEE 579

Query: 612 EWREAQKGFNKQWREQNEKYYLKSLDHQGINFKQNDLKAMRSKTLFNEVESAY------- 664
           EWREAQ+GFNK WREQ EK YLKSLDHQ +NFKQND KA+RSK+L NE+ES Y       
Sbjct: 580 EWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQH 639

Query: 665 ----AARRPGPHLVVDYNMQSRQEAIKIVRDTAELLIHHARRQTAIQKAEKRRIKQLLRH 720
               +A    PHL+  Y  + RQ    I+ D A L+ ++ +RQ AIQK ++  I QLL  
Sbjct: 640 SEGRSAPSSEPHLIFVY--EDRQ----ILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQ 693

Query: 721 FLPDLF 726
           F+P LF
Sbjct: 694 FVPSLF 699



 Score =  123 bits (296), Expect = 4e-27
 Identities = 54/83 (65%), Positives = 67/83 (80%)

Query: 51  VEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGVITRVSNLFKGHPELIVGF 110
           VEDAL+YLDQVK +F + P  YN FL+IMKEFKSQ+IDTPGVI RVS LF  HP+LIVGF
Sbjct: 41  VEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF 100

Query: 111 NTFLPPGYKIEVQSNGQVSVSMP 133
           N FLP GY+I++  NG++++  P
Sbjct: 101 NAFLPLGYRIDIPKNGKLNIQSP 123



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 26/88 (29%), Positives = 49/88 (55%), Gaps = 10/88 (11%)

Query: 49  LKVEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPG----------VITRVSN 98
           ++  +A+SY++++K +F   P++Y  FL+I+  ++ + ++T G          V T V+N
Sbjct: 160 VEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVAN 219

Query: 99  LFKGHPELIVGFNTFLPPGYKIEVQSNG 126
           LF+G  +L+  F  FLP   +     NG
Sbjct: 220 LFRGQEDLLSEFGQFLPEAKRSLFTGNG 247



 Score = 37.5 bits (83), Expect = 0.25
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 10/72 (13%)

Query: 210 AIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKLFEHQ 269
           A+ Y++++K RF   P  Y  FLEI          +KE +++      V  +V++LF   
Sbjct: 44  ALTYLDQVKIRFGSDPATYNGFLEI----------MKEFKSQSIDTPGVIRRVSQLFHEH 93

Query: 270 EDLLAEFGQFLP 281
            DL+  F  FLP
Sbjct: 94  PDLIVGFNAFLP 105



 Score = 34.7 bits (76), Expect = 1.7
 Identities = 16/45 (35%), Positives = 22/45 (48%)

Query: 912 EYYXXXXXXXXXXXXXXMESSAFEDAAREMLGIKAYPAYTLDKLV 956
           EYY              ++ + +ED  REM  I AY  +T+DKLV
Sbjct: 846 EYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLV 890


>AK027559-1|BAB55197.1| 1026|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14653 fis, clone NT2RP2002252, highly similar to
           Mus musculus (clone pVZmSin3A9) mSin3A9 mRNA. ).
          Length = 1026

 Score =  382 bits (941), Expect = e-105
 Identities = 212/423 (50%), Positives = 270/423 (63%), Gaps = 48/423 (11%)

Query: 323 VRDVSYSEAAKLATIHDYSFFERARKALRSQQVYDNFLRCLLLFTNEIISSSELLSVTSP 382
           ++D S ++A+K     +  FF++ RKALRS + Y+NFLRCL      +I + E++S    
Sbjct: 447 LKDSSMADASKHGGGTESLFFDKVRKALRSAEAYENFLRCL------VIFNQEVIS---- 496

Query: 383 FLCRHPELQRWLHDFVGXXXXXXXXXXXXXXGYPWTNPIPVEPRPRYESVGALGAQMRND 442
                 EL + +  F+G              GY     + +E  P+             +
Sbjct: 497 ----RAELVQLVSPFLGKFPELFNWFKNFL-GYK--ESVHLETYPK-------------E 536

Query: 443 RPQGDMAMDIDLSTCKRLGTSYCALPREAAARKCSGRTPLCKEVLNDTWVSFPTWSEDST 502
           R    +AM+ID ++CKRLG+SY ALP+     KC+GRTPLCKEVLNDTWVSFP+WSEDST
Sbjct: 537 RATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDST 596

Query: 503 FVTSRKTQYEEYIYRCEDERFELDVVIETNAATIRVLEGVQKKLSRMSGEDAARYRLDDC 562
           FV+S+KTQYEE+IYRCEDERFELDVV+ETN ATIRVLE +QKKLSR+S E+ A++RLD+ 
Sbjct: 597 FVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNT 656

Query: 563 LGGHSPTVHQRALRRIYGDKVAVDIIAGXXXXXXXXXXXXXXXXXXKEEEWREAQKGFNK 622
           LGG S  +H++AL+RIY DK A DII G                  KEEEWREAQ+GFNK
Sbjct: 657 LGGTSEVIHRKALQRIYADK-AADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNK 715

Query: 623 QWREQNEKYYLKSLDHQGINFKQNDLKAMRSKTLFNEVESAYAARRP-----------GP 671
            WREQNEKYYLKSLDHQGINFKQND K +RSK+L NE+ES Y  R+            GP
Sbjct: 716 VWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGP 775

Query: 672 HLVVDYNMQSRQEAIKIVRDTAELLIHHARRQTAIQKAEKRRIKQLLRHFLPDLFSHPRQ 731
           HL + Y      E  +I+ D A L+IHH +RQT IQK +K +IKQ++ HF+PDL    R 
Sbjct: 776 HLSLAY------EDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRG 829

Query: 732 PLS 734
            LS
Sbjct: 830 DLS 832



 Score =  247 bits (604), Expect = 2e-64
 Identities = 142/269 (52%), Positives = 163/269 (60%), Gaps = 28/269 (10%)

Query: 45  QFQRLKVEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGVITRVSNLFKGHP 104
           QFQRLKVEDALSYLDQVK +F +QPQVYNDFLDIMKEFKSQ+IDTPGVI+RVS LFKGHP
Sbjct: 117 QFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHP 176

Query: 105 ELIVGFNTFLPPGYKIEVQSNGQVSVSMPS-----PT-AIGSGVLLGVHHTQQPQL---- 154
           +LI+GFNTFLPPGYKIEVQ+N  V+V+ P      PT  I         H  QP      
Sbjct: 177 DLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAP 236

Query: 155 VHLLPVP---------------HAEECRPVGPALQHLSHAAPDPALHHXXXXXXXXXXXX 199
               P P               H    +   P   + S  +P    H             
Sbjct: 237 APAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSL 296

Query: 200 XXXXXXEFNHAIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQ---TEQ 256
                 EFNHAI YVNKIK+RF  QPD YK FLEILH YQ+  R+ KE         TEQ
Sbjct: 297 QNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQ 356

Query: 257 EVYSQVAKLFEHQEDLLAEFGQFLPDAKA 285
           EVY+QVA+LF++QEDLL+EFGQFLPDA +
Sbjct: 357 EVYAQVARLFKNQEDLLSEFGQFLPDANS 385



 Score = 37.9 bits (84), Expect = 0.19
 Identities = 18/49 (36%), Positives = 26/49 (53%)

Query: 912  EYYXXXXXXXXXXXXXXMESSAFEDAAREMLGIKAYPAYTLDKLVSIAV 960
            +YY              ++SS +ED+ REM  I AY A+T+DKL+   V
Sbjct: 957  DYYPAFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIV 1005


>AF418569-1|AAP97288.1| 1273|Homo sapiens MSIN3A protein.
          Length = 1273

 Score =  382 bits (941), Expect = e-105
 Identities = 212/423 (50%), Positives = 270/423 (63%), Gaps = 48/423 (11%)

Query: 323 VRDVSYSEAAKLATIHDYSFFERARKALRSQQVYDNFLRCLLLFTNEIISSSELLSVTSP 382
           ++D S ++A+K     +  FF++ RKALRS + Y+NFLRCL      +I + E++S    
Sbjct: 447 LKDSSMADASKHGGGTESLFFDKVRKALRSAEAYENFLRCL------VIFNQEVIS---- 496

Query: 383 FLCRHPELQRWLHDFVGXXXXXXXXXXXXXXGYPWTNPIPVEPRPRYESVGALGAQMRND 442
                 EL + +  F+G              GY     + +E  P+             +
Sbjct: 497 ----RAELVQLVSPFLGKFPELFNWFKNFL-GYK--ESVHLETYPK-------------E 536

Query: 443 RPQGDMAMDIDLSTCKRLGTSYCALPREAAARKCSGRTPLCKEVLNDTWVSFPTWSEDST 502
           R    +AM+ID ++CKRLG+SY ALP+     KC+GRTPLCKEVLNDTWVSFP+WSEDST
Sbjct: 537 RATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDST 596

Query: 503 FVTSRKTQYEEYIYRCEDERFELDVVIETNAATIRVLEGVQKKLSRMSGEDAARYRLDDC 562
           FV+S+KTQYEE+IYRCEDERFELDVV+ETN ATIRVLE +QKKLSR+S E+ A++RLD+ 
Sbjct: 597 FVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNT 656

Query: 563 LGGHSPTVHQRALRRIYGDKVAVDIIAGXXXXXXXXXXXXXXXXXXKEEEWREAQKGFNK 622
           LGG S  +H++AL+RIY DK A DII G                  KEEEWREAQ+GFNK
Sbjct: 657 LGGTSEVIHRKALQRIYADK-AADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNK 715

Query: 623 QWREQNEKYYLKSLDHQGINFKQNDLKAMRSKTLFNEVESAYAARRP-----------GP 671
            WREQNEKYYLKSLDHQGINFKQND K +RSK+L NE+ES Y  R+            GP
Sbjct: 716 VWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGP 775

Query: 672 HLVVDYNMQSRQEAIKIVRDTAELLIHHARRQTAIQKAEKRRIKQLLRHFLPDLFSHPRQ 731
           HL + Y      E  +I+ D A L+IHH +RQT IQK +K +IKQ++ HF+PDL    R 
Sbjct: 776 HLSLAY------EDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRG 829

Query: 732 PLS 734
            LS
Sbjct: 830 DLS 832



 Score =  247 bits (604), Expect = 2e-64
 Identities = 142/269 (52%), Positives = 163/269 (60%), Gaps = 28/269 (10%)

Query: 45  QFQRLKVEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGVITRVSNLFKGHP 104
           QFQRLKVEDALSYLDQVK +F +QPQVYNDFLDIMKEFKSQ+IDTPGVI+RVS LFKGHP
Sbjct: 117 QFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHP 176

Query: 105 ELIVGFNTFLPPGYKIEVQSNGQVSVSMPS-----PT-AIGSGVLLGVHHTQQPQL---- 154
           +LI+GFNTFLPPGYKIEVQ+N  V+V+ P      PT  I         H  QP      
Sbjct: 177 DLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAP 236

Query: 155 VHLLPVP---------------HAEECRPVGPALQHLSHAAPDPALHHXXXXXXXXXXXX 199
               P P               H    +   P   + S  +P    H             
Sbjct: 237 APAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSL 296

Query: 200 XXXXXXEFNHAIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQ---TEQ 256
                 EFNHAI YVNKIK+RF  QPD YK FLEILH YQ+  R+ KE         TEQ
Sbjct: 297 QNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQ 356

Query: 257 EVYSQVAKLFEHQEDLLAEFGQFLPDAKA 285
           EVY+QVA+LF++QEDLL+EFGQFLPDA +
Sbjct: 357 EVYAQVARLFKNQEDLLSEFGQFLPDANS 385



 Score = 37.9 bits (84), Expect = 0.19
 Identities = 18/49 (36%), Positives = 26/49 (53%)

Query: 912  EYYXXXXXXXXXXXXXXMESSAFEDAAREMLGIKAYPAYTLDKLVSIAV 960
            +YY              ++SS +ED+ REM  I AY A+T+DKL+   V
Sbjct: 957  DYYPAFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIV 1005


>AK096477-1|BAC04801.1|  810|Homo sapiens protein ( Homo sapiens
           cDNA FLJ39158 fis, clone OCBBF2002086, highly similar to
           Transcriptional regulator, SIN3A. ).
          Length = 810

 Score =  360 bits (885), Expect = 2e-98
 Identities = 201/400 (50%), Positives = 255/400 (63%), Gaps = 48/400 (12%)

Query: 323 VRDVSYSEAAKLATIHDYSFFERARKALRSQQVYDNFLRCLLLFTNEIISSSELLSVTSP 382
           ++D S ++A+K     +  FF++ RKALRS + Y+NFLRCL      +I + E++S    
Sbjct: 447 LKDSSMADASKHGGGTESLFFDKVRKALRSAEAYENFLRCL------VIFNQEVIS---- 496

Query: 383 FLCRHPELQRWLHDFVGXXXXXXXXXXXXXXGYPWTNPIPVEPRPRYESVGALGAQMRND 442
                 EL + +  F+G              GY     + +E  P+             +
Sbjct: 497 ----RAELVQLVSPFLGKFPELFNWFKNFL-GYK--ESVHLETYPK-------------E 536

Query: 443 RPQGDMAMDIDLSTCKRLGTSYCALPREAAARKCSGRTPLCKEVLNDTWVSFPTWSEDST 502
           R    +AM+ID ++CKRLG+SY ALP+     KC+GRTPLCKEVLNDTWVSFP+WSEDST
Sbjct: 537 RATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDST 596

Query: 503 FVTSRKTQYEEYIYRCEDERFELDVVIETNAATIRVLEGVQKKLSRMSGEDAARYRLDDC 562
           FV+S+KTQYEE+IYRCEDERFELDVV+ETN ATIRVLE +QKKLSR+S E+ A++RLD+ 
Sbjct: 597 FVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNT 656

Query: 563 LGGHSPTVHQRALRRIYGDKVAVDIIAGXXXXXXXXXXXXXXXXXXKEEEWREAQKGFNK 622
           LGG S  +H++AL+RIY DK A DII G                  KEEEWREAQ+GFNK
Sbjct: 657 LGGTSEVIHRKALQRIYADK-AADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNK 715

Query: 623 QWREQNEKYYLKSLDHQGINFKQNDLKAMRSKTLFNEVESAYAARRP-----------GP 671
            WREQNEKYYLKSLDHQGINFKQND K +RSK+L NE+ES Y  R+            GP
Sbjct: 716 VWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGP 775

Query: 672 HLVVDYNMQSRQEAIKIVRDTAELLIHHARRQTAIQKAEK 711
           HL + Y      E  +I+ D A L+IHH +RQT IQK +K
Sbjct: 776 HLSLAY------EDKQILEDAAALIIHHVKRQTGIQKEDK 809



 Score =  230 bits (563), Expect = 2e-59
 Identities = 136/269 (50%), Positives = 157/269 (58%), Gaps = 28/269 (10%)

Query: 45  QFQRLKVEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGVITRVSNLFKGHP 104
           QFQRLKVEDALSYLDQVK +F +QPQVYNDFLDIMKEFKSQ+IDTPGVI+RVS LFKGHP
Sbjct: 117 QFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHP 176

Query: 105 ELIVGFNTFLPPGYK--------IEVQSNGQVSV--------------SMPSPTAIGSGV 142
           +LI+GFNTFLPPGYK        + V + GQV                  PS  +  S  
Sbjct: 177 DLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGTQPQPQPPPQHPSQPSAQSAP 236

Query: 143 LLGVHHTQQPQLVHLLPVP---HAEECRPVGPALQHLSHAAPDPALHHXXXXXXXXXXXX 199
                  Q P      P     H    +   P   + S  +P    H             
Sbjct: 237 APAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSL 296

Query: 200 XXXXXXEFNHAIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQ---TEQ 256
                 EFNHAI YVNKIK+RF  QPD YK FLEILH YQ+  R+ KE         TEQ
Sbjct: 297 QNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQ 356

Query: 257 EVYSQVAKLFEHQEDLLAEFGQFLPDAKA 285
           EVY+QVA+LF++QEDLL+EFGQFLPDA +
Sbjct: 357 EVYAQVARLFKNQEDLLSEFGQFLPDANS 385


>AB014600-1|BAA31675.2| 1137|Homo sapiens KIAA0700 protein protein.
          Length = 1137

 Score =  324 bits (795), Expect = 1e-87
 Identities = 166/297 (55%), Positives = 205/297 (69%), Gaps = 18/297 (6%)

Query: 441 NDRPQGDMAMDIDLSTCKRLGTSYCALPREAAARKCSGRTPLCKEVLNDTWVSFPTWSED 500
           +DR    ++ +ID ++CKR+G+SY ALP+     KCSGRT +CKEVLNDTWVSFP+WSED
Sbjct: 385 SDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKEVLNDTWVSFPSWSED 444

Query: 501 STFVTSRKTQYEEYIYRCEDERFELDVVIETNAATIRVLEGVQKKLSRMSGEDAARYRLD 560
           STFV+S+KT YEE ++RCEDERFELDVV+ETN ATIRVLE VQKKLSRM+ ED  ++RLD
Sbjct: 445 STFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLD 504

Query: 561 DCLGGHSPTVHQRALRRIYGDKVAVDIIAGXXXXXXXXXXXXXXXXXXKEEEWREAQKGF 620
           D LGG S  + +RA+ RIYGDK A +II                    KEEEWREAQ+GF
Sbjct: 505 DSLGGTSEVIQRRAIYRIYGDK-APEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGF 563

Query: 621 NKQWREQNEKYYLKSLDHQGINFKQNDLKAMRSKTLFNEVESAY-----------AARRP 669
           NK WREQ EK YLKSLDHQ +NFKQND KA+RSK+L NE+ES Y           +A   
Sbjct: 564 NKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSS 623

Query: 670 GPHLVVDYNMQSRQEAIKIVRDTAELLIHHARRQTAIQKAEKRRIKQLLRHFLPDLF 726
            PHL+  Y  + RQ    I+ D A L+ ++ +RQ AIQK ++  I QLL  F+P LF
Sbjct: 624 EPHLIFVY--EDRQ----ILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLF 674



 Score =  154 bits (373), Expect = 2e-36
 Identities = 86/209 (41%), Positives = 120/209 (57%), Gaps = 17/209 (8%)

Query: 206 EFNHAIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKL 265
           EFN+AI YVNKIK+RF   P+ Y+ FLEILH YQ+   + +    +  +E+EV+++VA L
Sbjct: 168 EFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANL 227

Query: 266 FEHQEDLLAEFGQFLPDAK-------------AVTKPE--PAHEHHPMTFPTXXXXXXXX 310
           F  QEDLL+EFGQFLP+AK             +V K E     EH               
Sbjct: 228 FRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSA 287

Query: 311 XXXXXXCLSGATVRDVSYSEAAKLATIHDYSFFERARKALRSQQVYDNFLRCLLLFTNEI 370
                  L G   +D+S +   K  T+ ++SFF++ R+ L+SQ+VY+NFLRC+ LF  E+
Sbjct: 288 PAKKKMKLRG--TKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQEL 345

Query: 371 ISSSELLSVTSPFLCRHPELQRWLHDFVG 399
           +S SELL + SPFL + PEL      F+G
Sbjct: 346 VSGSELLQLVSPFLGKFPELFAQFKSFLG 374



 Score =  123 bits (296), Expect = 4e-27
 Identities = 54/83 (65%), Positives = 67/83 (80%)

Query: 51  VEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGVITRVSNLFKGHPELIVGF 110
           VEDAL+YLDQVK +F + P  YN FL+IMKEFKSQ+IDTPGVI RVS LF  HP+LIVGF
Sbjct: 48  VEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF 107

Query: 111 NTFLPPGYKIEVQSNGQVSVSMP 133
           N FLP GY+I++  NG++++  P
Sbjct: 108 NAFLPLGYRIDIPKNGKLNIQSP 130



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 26/88 (29%), Positives = 49/88 (55%), Gaps = 10/88 (11%)

Query: 49  LKVEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPG----------VITRVSN 98
           ++  +A+SY++++K +F   P++Y  FL+I+  ++ + ++T G          V T V+N
Sbjct: 167 VEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVAN 226

Query: 99  LFKGHPELIVGFNTFLPPGYKIEVQSNG 126
           LF+G  +L+  F  FLP   +     NG
Sbjct: 227 LFRGQEDLLSEFGQFLPEAKRSLFTGNG 254



 Score = 37.5 bits (83), Expect = 0.25
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 10/72 (13%)

Query: 210 AIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKLFEHQ 269
           A+ Y++++K RF   P  Y  FLEI          +KE +++      V  +V++LF   
Sbjct: 51  ALTYLDQVKIRFGSDPATYNGFLEI----------MKEFKSQSIDTPGVIRRVSQLFHEH 100

Query: 270 EDLLAEFGQFLP 281
            DL+  F  FLP
Sbjct: 101 PDLIVGFNAFLP 112



 Score = 34.7 bits (76), Expect = 1.7
 Identities = 16/45 (35%), Positives = 22/45 (48%)

Query: 912 EYYXXXXXXXXXXXXXXMESSAFEDAAREMLGIKAYPAYTLDKLV 956
           EYY              ++ + +ED  REM  I AY  +T+DKLV
Sbjct: 821 EYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLV 865


>AY044430-1|AAK95854.1|  621|Homo sapiens transcriptional
           co-repressor Sin3A protein.
          Length = 621

 Score =  208 bits (507), Expect = 1e-52
 Identities = 130/270 (48%), Positives = 153/270 (56%), Gaps = 29/270 (10%)

Query: 45  QFQRLKVEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGVITRVSNLFKGHP 104
           QFQRLKVEDALSYLDQVK +F +QPQVYNDFLDIMKEFKSQ+IDTP VI+RVS+  KG P
Sbjct: 117 QFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPRVISRVSHYSKGPP 176

Query: 105 ELIVGF-NTFLPPGYKIEVQSNGQVSVSMPS-----PT-AIGSGVLLGVHHTQQPQL--- 154
            LI+G  + F P   K+EVQ+N  V+V+ P      PT  I         H  QP     
Sbjct: 177 ILIMGIQHLFAPWATKMEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSA 236

Query: 155 -VHLLPVP---------------HAEECRPVGPALQHLSHAAPDPALHHXXXXXXXXXXX 198
                P P               H    +   P   + S  +P    H            
Sbjct: 237 PAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPS 296

Query: 199 XXXXXXXEFNHAIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQ---TE 255
                  EFNHAI YVNKIK+RF  QPD YK FLEILH YQ+  R+ KE         TE
Sbjct: 297 LQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTE 356

Query: 256 QEVYSQVAKLFEHQEDLLAEFGQFLPDAKA 285
           QEVY+QVA+LF++QEDLL+EFGQFLPDA +
Sbjct: 357 QEVYAQVARLFKNQEDLLSEFGQFLPDANS 386



 Score =  145 bits (351), Expect = 8e-34
 Identities = 87/203 (42%), Positives = 120/203 (59%), Gaps = 30/203 (14%)

Query: 323 VRDVSYSEAAKLATIHDYSFFERARKALRSQQVYDNFLRCLLLFTNEIISSSELLSVTSP 382
           ++D S ++A+K     +  FF++ RKALRS + Y+NFLRCL      +I + E++S    
Sbjct: 448 LKDSSMADASKHGGGTESLFFDKVRKALRSAEAYENFLRCL------VIFNQEVIS---- 497

Query: 383 FLCRHPELQRWLHDFVGXXXXXXXXXXXXXXGYPWTNPIPVEPRPRYESVGALGAQMRND 442
                 EL + +  F+G              GY     + +E  P+             D
Sbjct: 498 ----RAELVQLVSPFLGKFPELFNWFKNFL-GYK--ESVHLETYPK-------------D 537

Query: 443 RPQGDMAMDIDLSTCKRLGTSYCALPREAAARKCSGRTPLCKEVLNDTWVSFPTWSEDST 502
           R    +AM+ID ++CKRLG+SY AL +     KC+GRT +CKEVLNDTWVSFP+WSED T
Sbjct: 538 RATEGIAMEIDYASCKRLGSSYRALGKSYQQPKCTGRTGVCKEVLNDTWVSFPSWSEDCT 597

Query: 503 FVTSRKTQYEEYIYRCEDERFEL 525
           FV+S+KTQYEE+IYRCEDERF+L
Sbjct: 598 FVSSKKTQYEEHIYRCEDERFDL 620


>AK074903-1|BAC11280.1|  573|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90422 fis, clone NT2RP3000378, weakly similar to
           PAIRED AMPHIPATHIC HELIX PROTEIN. ).
          Length = 573

 Score =  155 bits (376), Expect = 8e-37
 Identities = 79/137 (57%), Positives = 94/137 (68%), Gaps = 17/137 (12%)

Query: 609 KEEEWREAQKGFNKQWREQNEKYYLKSLDHQGINFKQNDLKAMRSKTLFNEVESAYAARR 668
           KEEEWREAQ+GFNK WREQNEKYYLKSLDHQGINFKQND K +RSK+L NE+ES Y  R+
Sbjct: 2   KEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQ 61

Query: 669 P-----------GPHLVVDYNMQSRQEAIKIVRDTAELLIHHARRQTAIQKAEKRRIKQL 717
                       GPHL + Y      E  +I+ D A L+IHH +RQT IQK +K +IKQ+
Sbjct: 62  EQATEENAGVPVGPHLSLAY------EDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQI 115

Query: 718 LRHFLPDLFSHPRQPLS 734
           + HF+PDL    R  LS
Sbjct: 116 MHHFIPDLLFAQRGDLS 132



 Score = 37.9 bits (84), Expect = 0.19
 Identities = 18/49 (36%), Positives = 26/49 (53%)

Query: 912 EYYXXXXXXXXXXXXXXMESSAFEDAAREMLGIKAYPAYTLDKLVSIAV 960
           +YY              ++SS +ED+ REM  I AY A+T+DKL+   V
Sbjct: 257 DYYPAFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIV 305


>BC110821-1|AAI10822.1|  353|Homo sapiens SIN3B protein protein.
          Length = 353

 Score =  146 bits (353), Expect = 5e-34
 Identities = 81/194 (41%), Positives = 113/194 (58%), Gaps = 17/194 (8%)

Query: 206 EFNHAIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKL 265
           EFN+AI YVNKIK+RF   P+ Y+ FLEILH YQ+   + +    +  +E+EV+++VA L
Sbjct: 161 EFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANL 220

Query: 266 FEHQEDLLAEFGQFLPDAK-------------AVTKPE--PAHEHHPMTFPTXXXXXXXX 310
           F  QEDLL+EFGQFLP+AK             +V K E     EH               
Sbjct: 221 FRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSA 280

Query: 311 XXXXXXCLSGATVRDVSYSEAAKLATIHDYSFFERARKALRSQQVYDNFLRCLLLFTNEI 370
                  L G   +D+S +   K  T+ ++SFF++ R+ L+SQ+VY+NFLRC+ LF  E+
Sbjct: 281 PAKKKMKLRG--TKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQEL 338

Query: 371 ISSSELLSVTSPFL 384
           +S SELL + SPFL
Sbjct: 339 VSGSELLQLVSPFL 352



 Score =  123 bits (296), Expect = 4e-27
 Identities = 54/83 (65%), Positives = 67/83 (80%)

Query: 51  VEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGVITRVSNLFKGHPELIVGF 110
           VEDAL+YLDQVK +F + P  YN FL+IMKEFKSQ+IDTPGVI RVS LF  HP+LIVGF
Sbjct: 41  VEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF 100

Query: 111 NTFLPPGYKIEVQSNGQVSVSMP 133
           N FLP GY+I++  NG++++  P
Sbjct: 101 NAFLPLGYRIDIPKNGKLNIQSP 123



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 26/88 (29%), Positives = 49/88 (55%), Gaps = 10/88 (11%)

Query: 49  LKVEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPG----------VITRVSN 98
           ++  +A+SY++++K +F   P++Y  FL+I+  ++ + ++T G          V T V+N
Sbjct: 160 VEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVAN 219

Query: 99  LFKGHPELIVGFNTFLPPGYKIEVQSNG 126
           LF+G  +L+  F  FLP   +     NG
Sbjct: 220 LFRGQEDLLSEFGQFLPEAKRSLFTGNG 247



 Score = 37.5 bits (83), Expect = 0.25
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 10/72 (13%)

Query: 210 AIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKLFEHQ 269
           A+ Y++++K RF   P  Y  FLEI          +KE +++      V  +V++LF   
Sbjct: 44  ALTYLDQVKIRFGSDPATYNGFLEI----------MKEFKSQSIDTPGVIRRVSQLFHEH 93

Query: 270 EDLLAEFGQFLP 281
            DL+  F  FLP
Sbjct: 94  PDLIVGFNAFLP 105


>BC063531-1|AAH63531.1|  353|Homo sapiens SIN3B protein protein.
          Length = 353

 Score =  146 bits (353), Expect = 5e-34
 Identities = 81/194 (41%), Positives = 113/194 (58%), Gaps = 17/194 (8%)

Query: 206 EFNHAIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKL 265
           EFN+AI YVNKIK+RF   P+ Y+ FLEILH YQ+   + +    +  +E+EV+++VA L
Sbjct: 161 EFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANL 220

Query: 266 FEHQEDLLAEFGQFLPDAK-------------AVTKPE--PAHEHHPMTFPTXXXXXXXX 310
           F  QEDLL+EFGQFLP+AK             +V K E     EH               
Sbjct: 221 FRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSA 280

Query: 311 XXXXXXCLSGATVRDVSYSEAAKLATIHDYSFFERARKALRSQQVYDNFLRCLLLFTNEI 370
                  L G   +D+S +   K  T+ ++SFF++ R+ L+SQ+VY+NFLRC+ LF  E+
Sbjct: 281 PAKKKMKLRG--TKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQEL 338

Query: 371 ISSSELLSVTSPFL 384
           +S SELL + SPFL
Sbjct: 339 VSGSELLQLVSPFL 352



 Score =  123 bits (296), Expect = 4e-27
 Identities = 54/83 (65%), Positives = 67/83 (80%)

Query: 51  VEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGVITRVSNLFKGHPELIVGF 110
           VEDAL+YLDQVK +F + P  YN FL+IMKEFKSQ+IDTPGVI RVS LF  HP+LIVGF
Sbjct: 41  VEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF 100

Query: 111 NTFLPPGYKIEVQSNGQVSVSMP 133
           N FLP GY+I++  NG++++  P
Sbjct: 101 NAFLPLGYRIDIPKNGKLNIQSP 123



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 26/88 (29%), Positives = 49/88 (55%), Gaps = 10/88 (11%)

Query: 49  LKVEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPG----------VITRVSN 98
           ++  +A+SY++++K +F   P++Y  FL+I+  ++ + ++T G          V T V+N
Sbjct: 160 VEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVAN 219

Query: 99  LFKGHPELIVGFNTFLPPGYKIEVQSNG 126
           LF+G  +L+  F  FLP   +     NG
Sbjct: 220 LFRGQEDLLSEFGQFLPEAKRSLFTGNG 247



 Score = 37.5 bits (83), Expect = 0.25
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 10/72 (13%)

Query: 210 AIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKLFEHQ 269
           A+ Y++++K RF   P  Y  FLEI          +KE +++      V  +V++LF   
Sbjct: 44  ALTYLDQVKIRFGSDPATYNGFLEI----------MKEFKSQSIDTPGVIRRVSQLFHEH 93

Query: 270 EDLLAEFGQFLP 281
            DL+  F  FLP
Sbjct: 94  PDLIVGFNAFLP 105


>BC025026-1|AAH25026.1|  352|Homo sapiens SIN3B protein protein.
          Length = 352

 Score =  146 bits (353), Expect = 5e-34
 Identities = 81/194 (41%), Positives = 113/194 (58%), Gaps = 17/194 (8%)

Query: 206 EFNHAIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKL 265
           EFN+AI YVNKIK+RF   P+ Y+ FLEILH YQ+   + +    +  +E+EV+++VA L
Sbjct: 160 EFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANL 219

Query: 266 FEHQEDLLAEFGQFLPDAK-------------AVTKPE--PAHEHHPMTFPTXXXXXXXX 310
           F  QEDLL+EFGQFLP+AK             +V K E     EH               
Sbjct: 220 FRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSA 279

Query: 311 XXXXXXCLSGATVRDVSYSEAAKLATIHDYSFFERARKALRSQQVYDNFLRCLLLFTNEI 370
                  L G   +D+S +   K  T+ ++SFF++ R+ L+SQ+VY+NFLRC+ LF  E+
Sbjct: 280 PAKKKMKLRG--TKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQEL 337

Query: 371 ISSSELLSVTSPFL 384
           +S SELL + SPFL
Sbjct: 338 VSGSELLQLVSPFL 351



 Score =  123 bits (296), Expect = 4e-27
 Identities = 54/83 (65%), Positives = 67/83 (80%)

Query: 51  VEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGVITRVSNLFKGHPELIVGF 110
           VEDAL+YLDQVK +F + P  YN FL+IMKEFKSQ+IDTPGVI RVS LF  HP+LIVGF
Sbjct: 40  VEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF 99

Query: 111 NTFLPPGYKIEVQSNGQVSVSMP 133
           N FLP GY+I++  NG++++  P
Sbjct: 100 NAFLPLGYRIDIPKNGKLNIQSP 122



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 26/88 (29%), Positives = 49/88 (55%), Gaps = 10/88 (11%)

Query: 49  LKVEDALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPG----------VITRVSN 98
           ++  +A+SY++++K +F   P++Y  FL+I+  ++ + ++T G          V T V+N
Sbjct: 159 VEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVAN 218

Query: 99  LFKGHPELIVGFNTFLPPGYKIEVQSNG 126
           LF+G  +L+  F  FLP   +     NG
Sbjct: 219 LFRGQEDLLSEFGQFLPEAKRSLFTGNG 246



 Score = 37.5 bits (83), Expect = 0.25
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 10/72 (13%)

Query: 210 AIEYVNKIKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKLFEHQ 269
           A+ Y++++K RF   P  Y  FLEI          +KE +++      V  +V++LF   
Sbjct: 43  ALTYLDQVKIRFGSDPATYNGFLEI----------MKEFKSQSIDTPGVIRRVSQLFHEH 92

Query: 270 EDLLAEFGQFLP 281
            DL+  F  FLP
Sbjct: 93  PDLIVGFNAFLP 104


>BC018973-1|AAH18973.1|  417|Homo sapiens SIN3A protein protein.
          Length = 417

 Score = 37.9 bits (84), Expect = 0.19
 Identities = 18/49 (36%), Positives = 26/49 (53%)

Query: 912 EYYXXXXXXXXXXXXXXMESSAFEDAAREMLGIKAYPAYTLDKLVSIAV 960
           +YY              ++SS +ED+ REM  I AY A+T+DKL+   V
Sbjct: 101 DYYPAFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIV 149


>AL117513-1|CAB55972.1|  361|Homo sapiens hypothetical protein
           protein.
          Length = 361

 Score = 37.9 bits (84), Expect = 0.19
 Identities = 18/49 (36%), Positives = 26/49 (53%)

Query: 912 EYYXXXXXXXXXXXXXXMESSAFEDAAREMLGIKAYPAYTLDKLVSIAV 960
           +YY              ++SS +ED+ REM  I AY A+T+DKL+   V
Sbjct: 45  DYYPAFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIV 93


>BC005113-1|AAH05113.1|  420|Homo sapiens SIN3B protein protein.
          Length = 420

 Score = 34.7 bits (76), Expect = 1.7
 Identities = 16/45 (35%), Positives = 22/45 (48%)

Query: 912 EYYXXXXXXXXXXXXXXMESSAFEDAAREMLGIKAYPAYTLDKLV 956
           EYY              ++ + +ED  REM  I AY  +T+DKLV
Sbjct: 104 EYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLV 148


>AF086762-1|AAF28400.1| 1111|Homo sapiens C11orf9 protein.
          Length = 1111

 Score = 34.7 bits (76), Expect = 1.7
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 5/75 (6%)

Query: 115 PPGYKIEVQSNGQVSVSMPSP--TAIGSGVL-LGVHHTQQPQLVHLLPVPHAEECRPVGP 171
           PP Y + +Q +  +    P P   A+G G++   +HHTQQ Q++H L   H  E  P  P
Sbjct: 186 PPHYPV-LQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAEL-PTHP 243

Query: 172 ALQHLSHAAPDPALH 186
           + +     +P   L+
Sbjct: 244 SKKRKHSESPPSTLN 258


>AB023171-1|BAA76798.2| 1183|Homo sapiens KIAA0954 protein protein.
          Length = 1183

 Score = 34.7 bits (76), Expect = 1.7
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 5/75 (6%)

Query: 115 PPGYKIEVQSNGQVSVSMPSP--TAIGSGVL-LGVHHTQQPQLVHLLPVPHAEECRPVGP 171
           PP Y + +Q +  +    P P   A+G G++   +HHTQQ Q++H L   H  E  P  P
Sbjct: 227 PPHYPV-LQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLLQQHGAEL-PTHP 284

Query: 172 ALQHLSHAAPDPALH 186
           + +     +P   L+
Sbjct: 285 SKKRKHSESPPSTLN 299


>BC117557-1|AAI17558.1| 1098|Homo sapiens GON4L protein protein.
          Length = 1098

 Score = 33.1 bits (72), Expect = 5.3
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 54  ALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGV--ITRVSNLFKGHPELIVGFN 111
           A +YL +V+      P  Y DFL ++ EF+S T     V     +  L +  P+L+  F 
Sbjct: 827 AQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFA 886

Query: 112 TFLPP 116
            FL P
Sbjct: 887 AFLLP 891


>BC064933-1|AAH64933.1|  719|Homo sapiens GON4L protein protein.
          Length = 719

 Score = 33.1 bits (72), Expect = 5.3
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 54  ALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGV--ITRVSNLFKGHPELIVGFN 111
           A +YL +V+      P  Y DFL ++ EF+S T     V     +  L +  P+L+  F 
Sbjct: 110 AQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFA 169

Query: 112 TFLPP 116
            FL P
Sbjct: 170 AFLLP 174


>AY335491-1|AAR01261.1| 2241|Homo sapiens GON4L isoform C protein.
          Length = 2241

 Score = 33.1 bits (72), Expect = 5.3
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 54   ALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGV--ITRVSNLFKGHPELIVGFN 111
            A +YL +V+      P  Y DFL ++ EF+S T     V     +  L +  P+L+  F 
Sbjct: 1631 AQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFA 1690

Query: 112  TFLPP 116
             FL P
Sbjct: 1691 AFLLP 1695


>AY335490-1|AAR01260.1| 2241|Homo sapiens GON4L isoform A protein.
          Length = 2241

 Score = 33.1 bits (72), Expect = 5.3
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 54   ALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGV--ITRVSNLFKGHPELIVGFN 111
            A +YL +V+      P  Y DFL ++ EF+S T     V     +  L +  P+L+  F 
Sbjct: 1631 AQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFA 1690

Query: 112  TFLPP 116
             FL P
Sbjct: 1691 AFLLP 1695


>AL162734-1|CAH71640.1| 1078|Homo sapiens novel protein protein.
          Length = 1078

 Score = 33.1 bits (72), Expect = 5.3
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 54  ALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGV--ITRVSNLFKGHPELIVGFN 111
           A +YL +V+      P  Y DFL ++ EF+S T     V     +  L +  P+L+  F 
Sbjct: 469 AQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFA 528

Query: 112 TFLPP 116
            FL P
Sbjct: 529 AFLLP 533


>AL139128-1|CAH69942.1| 1078|Homo sapiens novel protein protein.
          Length = 1078

 Score = 33.1 bits (72), Expect = 5.3
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 54  ALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGV--ITRVSNLFKGHPELIVGFN 111
           A +YL +V+      P  Y DFL ++ EF+S T     V     +  L +  P+L+  F 
Sbjct: 469 AQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFA 528

Query: 112 TFLPP 116
            FL P
Sbjct: 529 AFLLP 533


>AK000210-1|BAA91011.1|  697|Homo sapiens protein ( Homo sapiens
           cDNA FLJ20203 fis, clone COLF1334. ).
          Length = 697

 Score = 33.1 bits (72), Expect = 5.3
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 54  ALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGV--ITRVSNLFKGHPELIVGFN 111
           A +YL +V+      P  Y DFL ++ EF+S T     V     +  L +  P+L+  F 
Sbjct: 88  AQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFA 147

Query: 112 TFLPP 116
            FL P
Sbjct: 148 AFLLP 152


>AB195687-1|BAF51556.1| 2240|Homo sapiens YY1AP-related protein1
            protein.
          Length = 2240

 Score = 33.1 bits (72), Expect = 5.3
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 54   ALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGV--ITRVSNLFKGHPELIVGFN 111
            A +YL +V+      P  Y DFL ++ EF+S T     V     +  L +  P+L+  F 
Sbjct: 1631 AQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFA 1690

Query: 112  TFLPP 116
             FL P
Sbjct: 1691 AFLLP 1695


>AB046826-1|BAB13432.1| 1095|Homo sapiens KIAA1606 protein protein.
          Length = 1095

 Score = 33.1 bits (72), Expect = 5.3
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 54  ALSYLDQVKYKFNTQPQVYNDFLDIMKEFKSQTIDTPGV--ITRVSNLFKGHPELIVGFN 111
           A +YL +V+      P  Y DFL ++ EF+S T     V     +  L +  P+L+  F 
Sbjct: 486 AQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFA 545

Query: 112 TFLPP 116
            FL P
Sbjct: 546 AFLLP 550


>L06845-1|AAA73901.1|  595|Homo sapiens cysteinyl-tRNA synthetase
           protein.
          Length = 595

 Score = 32.7 bits (71), Expect = 7.0
 Identities = 19/60 (31%), Positives = 30/60 (50%)

Query: 217 IKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKLFEHQEDLLAEF 276
           +K   +  PDK +    I HA Q     L++    + T +EV S V  L E  +DLL+++
Sbjct: 95  VKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDW 154


>BT009913-1|AAP88915.1|  748|Homo sapiens cysteinyl-tRNA synthetase
           protein.
          Length = 748

 Score = 32.7 bits (71), Expect = 7.0
 Identities = 19/60 (31%), Positives = 30/60 (50%)

Query: 217 IKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKLFEHQEDLLAEF 276
           +K   +  PDK +    I HA Q     L++    + T +EV S V  L E  +DLL+++
Sbjct: 138 VKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDW 197


>BC002880-1|AAH02880.1|  748|Homo sapiens cysteinyl-tRNA synthetase
           protein.
          Length = 748

 Score = 32.7 bits (71), Expect = 7.0
 Identities = 19/60 (31%), Positives = 30/60 (50%)

Query: 217 IKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKLFEHQEDLLAEF 276
           +K   +  PDK +    I HA Q     L++    + T +EV S V  L E  +DLL+++
Sbjct: 138 VKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDW 197


>AK222614-1|BAD96334.1|  726|Homo sapiens cysteine-tRNA ligase
           isoform a variant protein.
          Length = 726

 Score = 32.7 bits (71), Expect = 7.0
 Identities = 19/60 (31%), Positives = 30/60 (50%)

Query: 217 IKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKLFEHQEDLLAEF 276
           +K   +  PDK +    I HA Q     L++    + T +EV S V  L E  +DLL+++
Sbjct: 138 VKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDW 197


>AF288207-1|AAG00579.1|  726|Homo sapiens cysteinyl-tRNA synthetase
           protein.
          Length = 726

 Score = 32.7 bits (71), Expect = 7.0
 Identities = 19/60 (31%), Positives = 30/60 (50%)

Query: 217 IKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKLFEHQEDLLAEF 276
           +K   +  PDK +    I HA Q     L++    + T +EV S V  L E  +DLL+++
Sbjct: 138 VKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDW 197


>AF288206-1|AAG00578.1|  748|Homo sapiens cytoplasmic cysteinyl-tRNA
           synthetase protein.
          Length = 748

 Score = 32.7 bits (71), Expect = 7.0
 Identities = 19/60 (31%), Positives = 30/60 (50%)

Query: 217 IKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKLFEHQEDLLAEF 276
           +K   +  PDK +    I HA Q     L++    + T +EV S V  L E  +DLL+++
Sbjct: 138 VKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDW 197


>AB208814-1|BAD92051.1|  281|Homo sapiens cysteine-tRNA ligase
           isoform b variant protein.
          Length = 281

 Score = 32.7 bits (71), Expect = 7.0
 Identities = 19/60 (31%), Positives = 30/60 (50%)

Query: 217 IKSRFSRQPDKYKRFLEILHAYQRGHRDLKEPQAKQQTEQEVYSQVAKLFEHQEDLLAEF 276
           +K   +  PDK +    I HA Q     L++    + T +EV S V  L E  +DLL+++
Sbjct: 158 VKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDW 217


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.318    0.134    0.402 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 122,623,352
Number of Sequences: 224733
Number of extensions: 4602218
Number of successful extensions: 13873
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 13737
Number of HSP's gapped (non-prelim): 114
length of query: 1039
length of database: 73,234,838
effective HSP length: 97
effective length of query: 942
effective length of database: 51,435,737
effective search space: 48452464254
effective search space used: 48452464254
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 70 (32.3 bits)

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