Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000198-TA|BGIBMGA000198-PA|IPR000719|Protein kinase,
IPR011009|Protein kinase-like, IPR002290|Serine/threonine protein
kinase
(543 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q8INU8 Cluster: CG2615-PB, isoform B; n=14; Eumetazoa|R... 620 e-176
UniRef50_Q4H3C0 Cluster: IkappaB kinase; n=2; Ciona intestinalis... 483 e-135
UniRef50_Q9UHD2 Cluster: Serine/threonine-protein kinase TBK1; n... 440 e-122
UniRef50_Q14164 Cluster: Inhibitor of nuclear factor kappa-B kin... 427 e-118
UniRef50_Q6DGE5 Cluster: Zgc:100844; n=3; Danio rerio|Rep: Zgc:1... 407 e-112
UniRef50_Q4SRA2 Cluster: Chromosome 11 SCAF14528, whole genome s... 397 e-109
UniRef50_UPI0000E4740B Cluster: PREDICTED: similar to IkappaB ki... 390 e-107
UniRef50_UPI0000E4A8B8 Cluster: PREDICTED: similar to IkappaB ki... 376 e-103
UniRef50_UPI0000E1EF55 Cluster: PREDICTED: IKK-related kinase ep... 340 5e-92
UniRef50_Q4TD09 Cluster: Chromosome undetermined SCAF6590, whole... 252 1e-65
UniRef50_UPI000065D755 Cluster: SPFH domain-containing protein 1... 135 3e-30
UniRef50_Q2VU38 Cluster: IKK-like protein; n=4; Coelomata|Rep: I... 130 1e-28
UniRef50_Q294U5 Cluster: GA18025-PA; n=1; Drosophila pseudoobscu... 123 1e-26
UniRef50_O15111 Cluster: Inhibitor of nuclear factor kappa-B kin... 121 6e-26
UniRef50_O14920 Cluster: Inhibitor of nuclear factor kappa-B kin... 120 7e-26
UniRef50_UPI000150A1D4 Cluster: Protein kinase domain containing... 119 2e-25
UniRef50_Q22LY2 Cluster: Protein kinase domain containing protei... 119 2e-25
UniRef50_UPI0000519C1C Cluster: PREDICTED: similar to Inhibitor ... 116 2e-24
UniRef50_UPI0000E46D98 Cluster: PREDICTED: similar to doublecort... 115 4e-24
UniRef50_Q23R88 Cluster: Protein kinase domain containing protei... 115 4e-24
UniRef50_Q4RSR9 Cluster: Chromosome 12 SCAF14999, whole genome s... 114 6e-24
UniRef50_UPI0000D57829 Cluster: PREDICTED: similar to inhibitor ... 113 9e-24
UniRef50_Q229U9 Cluster: Protein kinase domain containing protei... 111 3e-23
UniRef50_UPI0000F1ECF4 Cluster: PREDICTED: hypothetical protein;... 110 1e-22
UniRef50_Q9VEZ5 Cluster: Inhibitor of nuclear factor kappa-B kin... 110 1e-22
UniRef50_Q24FQ7 Cluster: Protein kinase domain containing protei... 109 1e-22
UniRef50_A0BC68 Cluster: Chromosome undetermined scaffold_10, wh... 109 2e-22
UniRef50_Q8MQJ7 Cluster: LD18893p; n=4; Drosophila|Rep: LD18893p... 108 3e-22
UniRef50_A5PLA2 Cluster: LOC558848 protein; n=2; Clupeocephala|R... 108 4e-22
UniRef50_Q388H2 Cluster: Protein kinase, putative; n=1; Trypanos... 108 4e-22
UniRef50_Q54MH0 Cluster: Putative uncharacterized protein fhkD; ... 107 6e-22
UniRef50_A0DUI6 Cluster: Chromosome undetermined scaffold_64, wh... 107 6e-22
UniRef50_A0DQ68 Cluster: Chromosome undetermined scaffold_6, who... 107 6e-22
UniRef50_Q23R97 Cluster: Protein kinase domain containing protei... 107 7e-22
UniRef50_Q4RYN4 Cluster: Chromosome 16 SCAF14974, whole genome s... 107 1e-21
UniRef50_A7PNU0 Cluster: Chromosome chr8 scaffold_23, whole geno... 107 1e-21
UniRef50_Q4N591 Cluster: Calcium-dependent protein kinase, putat... 106 2e-21
UniRef50_Q22C77 Cluster: Protein kinase domain containing protei... 106 2e-21
UniRef50_A0CNU2 Cluster: Chromosome undetermined scaffold_22, wh... 106 2e-21
UniRef50_Q6BFB4 Cluster: Protein kinase, putative; n=3; Parameci... 105 2e-21
UniRef50_P11799 Cluster: Myosin light chain kinase, smooth muscl... 105 2e-21
UniRef50_UPI0000E48847 Cluster: PREDICTED: similar to titin isof... 105 3e-21
UniRef50_Q6PDN3 Cluster: Myosin light chain kinase, smooth muscl... 105 3e-21
UniRef50_UPI00015B6173 Cluster: PREDICTED: similar to ikk-like p... 105 4e-21
UniRef50_Q8IDV5 Cluster: Calcium-dependent protein kinase; n=7; ... 105 4e-21
UniRef50_Q23FR5 Cluster: Protein kinase domain containing protei... 105 4e-21
UniRef50_O45818 Cluster: Putative uncharacterized protein; n=1; ... 105 4e-21
UniRef50_A7RGL2 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ... 105 4e-21
UniRef50_A0BJ35 Cluster: Chromosome undetermined scaffold_11, wh... 105 4e-21
UniRef50_Q761X0 Cluster: Putative uncharacterized protein; n=2; ... 104 5e-21
UniRef50_A7PBE5 Cluster: Chromosome chr16 scaffold_10, whole gen... 104 7e-21
UniRef50_Q22S16 Cluster: Protein kinase domain containing protei... 104 7e-21
UniRef50_A0DNC5 Cluster: Chromosome undetermined scaffold_58, wh... 104 7e-21
UniRef50_A4RK67 Cluster: Putative uncharacterized protein; n=1; ... 104 7e-21
UniRef50_Q9SX42 Cluster: F14I3.15 protein; n=2; Arabidopsis thal... 103 9e-21
UniRef50_Q2QAV0 Cluster: Fused; n=3; core eudicotyledons|Rep: Fu... 103 9e-21
UniRef50_A0E776 Cluster: Chromosome undetermined scaffold_80, wh... 103 9e-21
UniRef50_A0C9W0 Cluster: Chromosome undetermined scaffold_16, wh... 103 9e-21
UniRef50_Q75CE9 Cluster: ACR142Wp; n=1; Eremothecium gossypii|Re... 103 9e-21
UniRef50_Q8IYT8 Cluster: Serine/threonine-protein kinase ULK2; n... 103 9e-21
UniRef50_O75385 Cluster: Serine/threonine-protein kinase ULK1; n... 103 9e-21
UniRef50_Q10292 Cluster: Meiosis-specific serine/threonine-prote... 103 9e-21
UniRef50_A7ANH6 Cluster: Protein kinase domain containing protei... 103 1e-20
UniRef50_A2DLZ6 Cluster: AGC family protein kinase; n=1; Trichom... 103 1e-20
UniRef50_A0C9C9 Cluster: Chromosome undetermined scaffold_16, wh... 103 1e-20
UniRef50_Q869W6 Cluster: Similar to Xenopus laevis (African claw... 103 2e-20
UniRef50_A7RI47 Cluster: Predicted protein; n=1; Nematostella ve... 103 2e-20
UniRef50_A0C1C8 Cluster: Chromosome undetermined scaffold_141, w... 102 2e-20
UniRef50_Q15746 Cluster: Myosin light chain kinase, smooth muscl... 102 2e-20
UniRef50_UPI00005A4286 Cluster: PREDICTED: similar to doublecort... 102 3e-20
UniRef50_Q24DL4 Cluster: Protein kinase domain containing protei... 102 3e-20
UniRef50_UPI0000D8B5E1 Cluster: Unc-51 like kinase 2 (C. elegans... 101 4e-20
UniRef50_Q6BFK9 Cluster: SNF1-related protein kinase, putative; ... 101 4e-20
UniRef50_A0CDT9 Cluster: Chromosome undetermined scaffold_17, wh... 101 4e-20
UniRef50_UPI0000E809AA Cluster: PREDICTED: similar to regulated ... 101 5e-20
UniRef50_UPI0000D555E5 Cluster: PREDICTED: similar to CG7717-PB,... 101 5e-20
UniRef50_Q235N6 Cluster: Protein kinase domain containing protei... 101 6e-20
UniRef50_Q54BF0 Cluster: Putative uncharacterized protein fhkA; ... 100 9e-20
UniRef50_A0DN99 Cluster: Chromosome undetermined scaffold_57, wh... 100 9e-20
UniRef50_A0C1X6 Cluster: Chromosome undetermined scaffold_143, w... 100 9e-20
UniRef50_Q96NX5 Cluster: Calcium/calmodulin-dependent protein ki... 100 9e-20
UniRef50_UPI0001554A4C Cluster: PREDICTED: hypothetical protein;... 100 1e-19
UniRef50_UPI00006CBD17 Cluster: Protein kinase domain containing... 100 1e-19
UniRef50_Q6BFF5 Cluster: Protein kinase, putative; n=2; Parameci... 100 1e-19
UniRef50_Q5CTY5 Cluster: Calcium/calmodulin dependent protein ki... 100 1e-19
UniRef50_A0D911 Cluster: Chromosome undetermined scaffold_41, wh... 100 1e-19
UniRef50_A0C9K2 Cluster: Chromosome undetermined scaffold_16, wh... 100 1e-19
UniRef50_A0C5A6 Cluster: Chromosome undetermined scaffold_15, wh... 100 1e-19
UniRef50_UPI00006CC451 Cluster: Protein kinase domain containing... 99 1e-19
UniRef50_Q240Z1 Cluster: Protein kinase domain containing protei... 99 1e-19
UniRef50_Q19A76 Cluster: Checkpoint kinase 2-like; n=12; Pezizom... 99 1e-19
UniRef50_UPI00006CB13C Cluster: Protein kinase domain containing... 100 2e-19
UniRef50_Q9VE37 Cluster: CG7717-PA, isoform A; n=6; Eumetazoa|Re... 100 2e-19
UniRef50_Q54PX0 Cluster: Putative uncharacterized protein; n=1; ... 100 2e-19
UniRef50_A2E7E2 Cluster: CAMK family protein kinase; n=1; Tricho... 100 2e-19
UniRef50_Q5K8X6 Cluster: Protein threonine/tyrosine kinase, puta... 100 2e-19
UniRef50_Q9P7I2 Cluster: Calcium/calmodulin-dependent protein ki... 100 2e-19
UniRef50_UPI00015B5E56 Cluster: PREDICTED: similar to myosin lig... 99 3e-19
UniRef50_Q8MYF1 Cluster: Similar to Dictyostelium discoideum (Sl... 99 3e-19
UniRef50_Q24HR9 Cluster: Protein kinase domain containing protei... 99 3e-19
UniRef50_Q56UN5 Cluster: SPS1/STE20-related protein kinase YSK4;... 99 3e-19
UniRef50_Q24HI1 Cluster: Protein kinase domain containing protei... 99 3e-19
UniRef50_Q17G02 Cluster: Inhibitor of nuclear factor kappa B kin... 99 3e-19
UniRef50_Q2UCX8 Cluster: Serine/threonine protein kinase Chk2 an... 99 3e-19
UniRef50_UPI0000DA406D Cluster: PREDICTED: similar to serine/thr... 98 5e-19
UniRef50_Q4SMN8 Cluster: Chromosome undetermined SCAF14546, whol... 98 5e-19
UniRef50_A2EUZ8 Cluster: CAMK family protein kinase; n=1; Tricho... 98 5e-19
UniRef50_A0E675 Cluster: Chromosome undetermined scaffold_8, who... 98 5e-19
UniRef50_Q15139 Cluster: Serine/threonine-protein kinase D1; n=5... 98 5e-19
UniRef50_UPI00004998A1 Cluster: protein kinase; n=1; Entamoeba h... 98 6e-19
UniRef50_Q4SFY0 Cluster: Chromosome 7 SCAF14601, whole genome sh... 98 6e-19
UniRef50_Q54TA3 Cluster: Putative uncharacterized protein mrkC; ... 98 6e-19
UniRef50_A3FQ16 Cluster: Calmodulin-domain protein kinase 1, put... 98 6e-19
UniRef50_Q9BZL6 Cluster: Serine/threonine-protein kinase D2; n=1... 98 6e-19
UniRef50_UPI00004D6BBB Cluster: Protein kinase C, nu type (EC 2.... 97 8e-19
UniRef50_Q7XTK4 Cluster: Putative mitogen-activated protein kina... 97 8e-19
UniRef50_A2FMG9 Cluster: AGC family protein kinase; n=2; Trichom... 97 8e-19
UniRef50_A0E0N1 Cluster: Chromosome undetermined scaffold_72, wh... 97 8e-19
UniRef50_A0CQE0 Cluster: Chromosome undetermined scaffold_24, wh... 97 8e-19
UniRef50_Q8IVW4 Cluster: Cyclin-dependent kinase-like 3; n=36; M... 97 8e-19
UniRef50_Q10SI6 Cluster: Protein kinase domain containing protei... 97 1e-18
UniRef50_A0DXN2 Cluster: Chromosome undetermined scaffold_69, wh... 97 1e-18
UniRef50_A0CJI6 Cluster: Chromosome undetermined scaffold_2, who... 97 1e-18
UniRef50_A0BUI0 Cluster: Chromosome undetermined scaffold_129, w... 97 1e-18
UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin ... 97 1e-18
UniRef50_Q4DSQ1 Cluster: Protein kinase, putative; n=2; Trypanos... 97 1e-18
UniRef50_Q86YV6 Cluster: Uncharacterized serine/threonine-protei... 97 1e-18
UniRef50_Q9C098 Cluster: Serine/threonine-protein kinase DCLK3; ... 97 1e-18
UniRef50_Q9JLM8 Cluster: Serine/threonine-protein kinase DCLK1; ... 97 1e-18
UniRef50_UPI00006CDDE2 Cluster: Protein kinase domain containing... 96 2e-18
UniRef50_Q2JQG2 Cluster: Serine/threonine protein kinase; n=2; S... 96 2e-18
UniRef50_Q6BG36 Cluster: SNF1-related protein kinase, putative; ... 96 2e-18
UniRef50_Q240Z4 Cluster: Protein kinase domain containing protei... 96 2e-18
UniRef50_A2F0J6 Cluster: AGC family protein kinase; n=1; Trichom... 96 2e-18
UniRef50_A0E574 Cluster: Chromosome undetermined scaffold_79, wh... 96 2e-18
UniRef50_A0CA86 Cluster: Chromosome undetermined scaffold_160, w... 96 2e-18
UniRef50_A0BJR0 Cluster: Chromosome undetermined scaffold_110, w... 96 2e-18
UniRef50_A7TJU8 Cluster: Putative uncharacterized protein; n=1; ... 96 2e-18
UniRef50_P41892 Cluster: Cell division control protein 7; n=1; S... 96 2e-18
UniRef50_A2AQX6 Cluster: Novel protein tyrosine kinase; n=2; Mus... 96 2e-18
UniRef50_Q9VE91 Cluster: CG7125-PA, isoform A; n=2; Diptera|Rep:... 96 2e-18
UniRef50_Q54SJ5 Cluster: Putative uncharacterized protein; n=1; ... 96 2e-18
UniRef50_Q4DIT1 Cluster: Protein kinase, putative; n=4; Trypanos... 96 2e-18
UniRef50_A0EAM0 Cluster: Chromosome undetermined scaffold_86, wh... 96 2e-18
UniRef50_A0C2X8 Cluster: Chromosome undetermined scaffold_145, w... 96 2e-18
UniRef50_A0C214 Cluster: Chromosome undetermined scaffold_143, w... 96 2e-18
UniRef50_A0BIC2 Cluster: Chromosome undetermined scaffold_11, wh... 96 2e-18
UniRef50_A6R025 Cluster: Predicted protein; n=1; Ajellomyces cap... 96 2e-18
UniRef50_P57058 Cluster: Hormonally up-regulated neu tumor-assoc... 96 2e-18
UniRef50_UPI00015562C7 Cluster: PREDICTED: similar to MLCK prote... 95 3e-18
UniRef50_UPI0000F1F5BA Cluster: PREDICTED: similar to novel kina... 95 3e-18
UniRef50_UPI00006CBF34 Cluster: Protein kinase domain containing... 95 3e-18
UniRef50_Q3V454 Cluster: 10 days embryo whole body cDNA, RIKEN f... 95 3e-18
UniRef50_A2ACR7 Cluster: Cyclin-dependent kinase-like 3; n=10; E... 95 3e-18
UniRef50_A3IW14 Cluster: Serine/threonine protein kinase; n=2; C... 95 3e-18
UniRef50_Q2QSC9 Cluster: Protein kinase domain containing protei... 95 3e-18
UniRef50_Q8WQ18 Cluster: Protein kinase; n=1; Nyctotherus ovalis... 95 3e-18
UniRef50_Q55CA6 Cluster: Putative uncharacterized protein; n=1; ... 95 3e-18
UniRef50_Q4E2U7 Cluster: Protein kinase, putative; n=2; Trypanos... 95 3e-18
UniRef50_A0D261 Cluster: Chromosome undetermined scaffold_35, wh... 95 3e-18
UniRef50_A0BXW7 Cluster: Chromosome undetermined scaffold_135, w... 95 3e-18
UniRef50_Q6IWN3 Cluster: P21-activated kinase Cla4; n=1; Ustilag... 95 3e-18
UniRef50_P11801 Cluster: Serine/threonine-protein kinase H1; n=3... 95 3e-18
UniRef50_UPI000150A956 Cluster: Protein kinase domain containing... 95 4e-18
UniRef50_A2BFU1 Cluster: Novel protein; n=6; Euteleostomi|Rep: N... 95 4e-18
UniRef50_Q9NH60 Cluster: Calcium/calmodulin-dependent protein ki... 95 4e-18
UniRef50_Q9NH59 Cluster: Calcium/calmodulin-dependent protein ki... 95 4e-18
UniRef50_Q9NH58 Cluster: Calcium/calmodulin-dependent protein ki... 95 4e-18
UniRef50_Q7QBH3 Cluster: ENSANGP00000014786; n=3; Culicidae|Rep:... 95 4e-18
UniRef50_Q3LDS4 Cluster: Carbon catabolite derepressing protein ... 95 4e-18
UniRef50_Q229R8 Cluster: Protein kinase domain containing protei... 95 4e-18
UniRef50_A2FCZ8 Cluster: CAMK family protein kinase; n=1; Tricho... 95 4e-18
UniRef50_A2DH03 Cluster: CAMK family protein kinase; n=1; Tricho... 95 4e-18
UniRef50_A0CYL8 Cluster: Chromosome undetermined scaffold_31, wh... 95 4e-18
UniRef50_A0CJD7 Cluster: Chromosome undetermined scaffold_2, who... 95 4e-18
UniRef50_A0BG89 Cluster: Chromosome undetermined scaffold_105, w... 95 4e-18
UniRef50_Q0VD65 Cluster: MYO3A protein; n=22; Euteleostomi|Rep: ... 95 4e-18
UniRef50_A3LSM4 Cluster: Predicted protein; n=1; Pichia stipitis... 95 4e-18
UniRef50_Q8NEV4 Cluster: Myosin IIIA; n=68; Coelomata|Rep: Myosi... 95 4e-18
UniRef50_P11730 Cluster: Calcium/calmodulin-dependent protein ki... 95 4e-18
UniRef50_Q13555 Cluster: Calcium/calmodulin-dependent protein ki... 95 4e-18
UniRef50_UPI0000D56DEC Cluster: PREDICTED: similar to CG10967-PA... 95 6e-18
UniRef50_UPI000069FC64 Cluster: Serine/threonine-protein kinase ... 95 6e-18
UniRef50_UPI000069FC63 Cluster: Serine/threonine-protein kinase ... 95 6e-18
UniRef50_Q9QYZ3 Cluster: Putative uncharacterized protein Smok; ... 95 6e-18
UniRef50_Q8IGZ0 Cluster: RE01659p; n=9; Endopterygota|Rep: RE016... 95 6e-18
UniRef50_A7S4Z6 Cluster: Predicted protein; n=1; Nematostella ve... 95 6e-18
UniRef50_A0DGC5 Cluster: Chromosome undetermined scaffold_5, who... 95 6e-18
UniRef50_A0CPJ3 Cluster: Chromosome undetermined scaffold_23, wh... 95 6e-18
UniRef50_Q4X028 Cluster: Protein kinase, putative; n=6; Trichoco... 95 6e-18
UniRef50_Q3UIZ8 Cluster: Putative myosin light chain kinase 3; n... 95 6e-18
UniRef50_O54784 Cluster: Death-associated protein kinase 3; n=16... 95 6e-18
UniRef50_UPI00015B6294 Cluster: PREDICTED: similar to myosin lig... 94 7e-18
UniRef50_UPI000155ED1B Cluster: PREDICTED: similar to serine/thr... 94 7e-18
UniRef50_UPI0000E80D72 Cluster: PREDICTED: similar to myosin lig... 94 7e-18
UniRef50_UPI0000E7FBCB Cluster: PREDICTED: similar to NIMA (neve... 94 7e-18
UniRef50_UPI0000ECB019 Cluster: UPI0000ECB019 related cluster; n... 94 7e-18
UniRef50_Q5BJ15 Cluster: Wu:fc83c01 protein; n=4; Danio rerio|Re... 94 7e-18
UniRef50_Q4XQ94 Cluster: Protein kinase, putative; n=1; Plasmodi... 94 7e-18
UniRef50_Q0KI87 Cluster: CG11870-PA, isoform A; n=3; Drosophila ... 94 7e-18
UniRef50_O43945 Cluster: MEKK-related kinase; n=4; Leishmania|Re... 94 7e-18
UniRef50_A0BX79 Cluster: Chromosome undetermined scaffold_134, w... 94 7e-18
UniRef50_Q39008 Cluster: Mitogen-activated protein kinase kinase... 94 7e-18
UniRef50_UPI000150A88D Cluster: Protein kinase domain containing... 94 1e-17
UniRef50_UPI0000F2C92F Cluster: PREDICTED: similar to serine/thr... 94 1e-17
UniRef50_UPI0000DB7011 Cluster: PREDICTED: similar to CG33519-PB... 94 1e-17
UniRef50_UPI00006CFB74 Cluster: Protein kinase domain containing... 94 1e-17
UniRef50_UPI00004983FA Cluster: protein kinase; n=1; Entamoeba h... 94 1e-17
UniRef50_A7UAR9 Cluster: Checkpoint kinase 2; n=1; Oncorhynchus ... 94 1e-17
UniRef50_Q16SX1 Cluster: Mitogen activated protein kinase kinase... 94 1e-17
UniRef50_A0C8K1 Cluster: Chromosome undetermined scaffold_158, w... 94 1e-17
UniRef50_A0BFB3 Cluster: Chromosome undetermined scaffold_103, w... 94 1e-17
UniRef50_Q9P8J0 Cluster: Map kinase kinase; n=1; Pneumocystis ca... 94 1e-17
UniRef50_Q756N1 Cluster: AER223Cp; n=1; Eremothecium gossypii|Re... 94 1e-17
UniRef50_A5E6H6 Cluster: Putative uncharacterized protein; n=1; ... 94 1e-17
UniRef50_Q9BYT3 Cluster: Serine/threonine-protein kinase 33; n=2... 94 1e-17
UniRef50_Q16566 Cluster: Calcium/calmodulin-dependent protein ki... 94 1e-17
UniRef50_Q9UIK4 Cluster: Death-associated protein kinase 2; n=4;... 94 1e-17
UniRef50_UPI000155CD84 Cluster: PREDICTED: similar to Mitogen-ac... 93 1e-17
UniRef50_UPI0000499847 Cluster: protein kinase; n=1; Entamoeba h... 93 1e-17
UniRef50_UPI000065E60F Cluster: STE20-like serine/threonine-prot... 93 1e-17
UniRef50_Q238Z8 Cluster: Protein kinase domain containing protei... 93 1e-17
UniRef50_Q22UA7 Cluster: Protein kinase domain containing protei... 93 1e-17
UniRef50_Q22AY1 Cluster: Protein kinase domain containing protei... 93 1e-17
UniRef50_A2DLE7 Cluster: CAMK family protein kinase; n=1; Tricho... 93 1e-17
UniRef50_A0D2H1 Cluster: Chromosome undetermined scaffold_35, wh... 93 1e-17
UniRef50_A0D0C4 Cluster: Chromosome undetermined scaffold_33, wh... 93 1e-17
UniRef50_Q9NRP7 Cluster: Serine/threonine-protein kinase 36; n=2... 93 1e-17
UniRef50_UPI0000DB6ED3 Cluster: PREDICTED: similar to CG17528-PC... 93 2e-17
UniRef50_UPI00004998B6 Cluster: cell division control protein 7;... 93 2e-17
UniRef50_UPI0000660530 Cluster: Serine/threonine-protein kinase ... 93 2e-17
UniRef50_A7PSB1 Cluster: Chromosome chr14 scaffold_27, whole gen... 93 2e-17
UniRef50_A5BPZ0 Cluster: Putative uncharacterized protein; n=1; ... 93 2e-17
UniRef50_Q5R1T9 Cluster: Cell cycle checkpoint kinase 2; n=1; Bo... 93 2e-17
UniRef50_Q4Q0M7 Cluster: Protein kinase, putative; n=3; Leishman... 93 2e-17
UniRef50_Q17C01 Cluster: Serine/threonine-protein kinase MAK; n=... 93 2e-17
UniRef50_A7RL88 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 93 2e-17
UniRef50_A0DX23 Cluster: Chromosome undetermined scaffold_68, wh... 93 2e-17
UniRef50_A0C3X2 Cluster: Chromosome undetermined scaffold_148, w... 93 2e-17
UniRef50_A0C060 Cluster: Chromosome undetermined scaffold_14, wh... 93 2e-17
UniRef50_A5DKU9 Cluster: Putative uncharacterized protein; n=1; ... 93 2e-17
UniRef50_Q6C3D7 Cluster: Serine/threonine-protein kinase STE20; ... 93 2e-17
UniRef50_UPI0000D5765F Cluster: PREDICTED: similar to CG14895-PA... 93 2e-17
UniRef50_UPI0000ECD6BF Cluster: Serine/threonine-protein kinase ... 93 2e-17
UniRef50_Q6ZM37 Cluster: Novel protein; n=2; Danio rerio|Rep: No... 93 2e-17
UniRef50_Q1LVF9 Cluster: Novel kinase domain containing protein;... 93 2e-17
UniRef50_A7NWI3 Cluster: Chromosome chr5 scaffold_2, whole genom... 93 2e-17
UniRef50_Q54CY9 Cluster: Putative uncharacterized protein; n=1; ... 93 2e-17
UniRef50_Q4N365 Cluster: Serine/threonine protein kinase, putati... 93 2e-17
UniRef50_Q24213 Cluster: P21-activated protein kinase 1 Dpak1; n... 93 2e-17
UniRef50_Q6BTM5 Cluster: Similar to CA4433|CaBCK1 Candida albica... 93 2e-17
UniRef50_O15865 Cluster: Calcium-dependent protein kinase 2; n=2... 93 2e-17
UniRef50_UPI0000F1EC26 Cluster: PREDICTED: hypothetical protein;... 92 3e-17
UniRef50_UPI00015A44B1 Cluster: hypothetical protein LOC325034; ... 92 3e-17
UniRef50_Q4RQ76 Cluster: Chromosome 17 SCAF15006, whole genome s... 92 3e-17
UniRef50_Q01I65 Cluster: H0315A08.7 protein; n=8; Oryza sativa|R... 92 3e-17
UniRef50_Q86GD6 Cluster: Projectin; n=1; Procambarus clarkii|Rep... 92 3e-17
UniRef50_Q4N248 Cluster: Protein kinase, putative; n=2; Theileri... 92 3e-17
UniRef50_Q235P0 Cluster: Protein kinase domain containing protei... 92 3e-17
UniRef50_A0EFS0 Cluster: Chromosome undetermined scaffold_94, wh... 92 3e-17
UniRef50_A0D293 Cluster: Chromosome undetermined scaffold_35, wh... 92 3e-17
UniRef50_A0CWQ7 Cluster: Chromosome undetermined scaffold_3, who... 92 3e-17
UniRef50_A0BWH0 Cluster: Chromosome undetermined scaffold_132, w... 92 3e-17
UniRef50_A3LNW8 Cluster: Predicted protein; n=5; Saccharomycetal... 92 3e-17
UniRef50_P22216 Cluster: Serine/threonine-protein kinase RAD53; ... 92 3e-17
UniRef50_Q6P3R8 Cluster: Serine/threonine-protein kinase Nek5; n... 92 3e-17
UniRef50_UPI0000E47761 Cluster: PREDICTED: similar to serine/thr... 92 4e-17
UniRef50_UPI0000D5575B Cluster: PREDICTED: similar to CG10951-PA... 92 4e-17
UniRef50_UPI00006CBA83 Cluster: Protein kinase domain containing... 92 4e-17
UniRef50_Q23ML0 Cluster: Protein kinase domain containing protei... 92 4e-17
UniRef50_Q23D11 Cluster: Protein kinase domain containing protei... 92 4e-17
UniRef50_Q22SK1 Cluster: Protein kinase domain containing protei... 92 4e-17
UniRef50_A2DB15 Cluster: AGC family protein kinase; n=1; Trichom... 92 4e-17
UniRef50_A0DH53 Cluster: Chromosome undetermined scaffold_50, wh... 92 4e-17
UniRef50_A0D1V1 Cluster: Chromosome undetermined scaffold_34, wh... 92 4e-17
UniRef50_Q99683 Cluster: Mitogen-activated protein kinase kinase... 92 4e-17
UniRef50_Q8N568 Cluster: Serine/threonine-protein kinase DCLK2; ... 92 4e-17
UniRef50_O22040 Cluster: Mitogen-activated protein kinase kinase... 92 4e-17
UniRef50_UPI0000F2D863 Cluster: PREDICTED: hypothetical protein;... 91 5e-17
UniRef50_Q9VGP9 Cluster: CG6715-PA; n=7; Sophophora|Rep: CG6715-... 91 5e-17
UniRef50_Q960A2 Cluster: Mtk1/mekk4 homolog protein 1, isoform b... 91 5e-17
UniRef50_Q7R3F6 Cluster: GLP_158_77856_75799; n=1; Giardia lambl... 91 5e-17
UniRef50_Q6PLK2 Cluster: Protein kinase B-like protein; n=4; Pla... 91 5e-17
UniRef50_Q5CHJ7 Cluster: Calcium-dependent protein kinase; n=4; ... 91 5e-17
UniRef50_Q54RV3 Cluster: Putative uncharacterized protein pakG; ... 91 5e-17
UniRef50_Q54R82 Cluster: Protein serine/threonine kinase; n=2; D... 91 5e-17
UniRef50_Q54MV2 Cluster: Putative uncharacterized protein mrkB; ... 91 5e-17
UniRef50_Q22XQ2 Cluster: Protein kinase domain containing protei... 91 5e-17
UniRef50_A2DV71 Cluster: CAMK family protein kinase; n=1; Tricho... 91 5e-17
UniRef50_A0D805 Cluster: Chromosome undetermined scaffold_40, wh... 91 5e-17
UniRef50_A0BKC9 Cluster: Chromosome undetermined scaffold_112, w... 91 5e-17
UniRef50_Q8SSH1 Cluster: SPK1-LIKE SER/THR PROTEIN KINASE; n=1; ... 91 5e-17
UniRef50_Q6BV63 Cluster: Debaryomyces hansenii chromosome C of s... 91 5e-17
UniRef50_O55092 Cluster: STE20-like serine/threonine-protein kin... 91 5e-17
UniRef50_UPI0000D56F77 Cluster: PREDICTED: similar to CG11870-PA... 91 7e-17
UniRef50_UPI000049857F Cluster: protein kinase; n=1; Entamoeba h... 91 7e-17
UniRef50_UPI0000D8B3E9 Cluster: UPI0000D8B3E9 related cluster; n... 91 7e-17
UniRef50_UPI00003AC2A2 Cluster: myosin light chain kinase 2, ske... 91 7e-17
UniRef50_Q9M9B8 Cluster: F27J15.5; n=4; core eudicotyledons|Rep:... 91 7e-17
UniRef50_Q57WI0 Cluster: Protein kinase, putative; n=1; Trypanos... 91 7e-17
UniRef50_Q4QGB0 Cluster: Mitogen-activated protein kinase kinase... 91 7e-17
UniRef50_A0E900 Cluster: Chromosome undetermined scaffold_83, wh... 91 7e-17
UniRef50_A0DCM5 Cluster: Chromosome undetermined scaffold_45, wh... 91 7e-17
UniRef50_A0D0Y6 Cluster: Chromosome undetermined scaffold_33, wh... 91 7e-17
UniRef50_O14757 Cluster: Serine/threonine-protein kinase Chk1; n... 91 7e-17
UniRef50_UPI00015B507B Cluster: PREDICTED: similar to cell cycle... 91 9e-17
UniRef50_Q4S904 Cluster: Chromosome 7 SCAF14703, whole genome sh... 91 9e-17
UniRef50_Q9LDQ1 Cluster: T12C24.12; n=4; core eudicotyledons|Rep... 91 9e-17
UniRef50_Q8I182 Cluster: Pk92B-PA; n=4; Endopterygota|Rep: Pk92B... 91 9e-17
UniRef50_Q22324 Cluster: Putative uncharacterized protein T07F12... 91 9e-17
UniRef50_Q1ZXH2 Cluster: Putative uncharacterized protein fhkB; ... 91 9e-17
UniRef50_A7ASW0 Cluster: Asparagine rich protein, putative; n=1;... 91 9e-17
UniRef50_A0E889 Cluster: Chromosome undetermined scaffold_82, wh... 91 9e-17
UniRef50_A0E7U8 Cluster: Chromosome undetermined scaffold_81, wh... 91 9e-17
UniRef50_A0E054 Cluster: Chromosome undetermined scaffold_71, wh... 91 9e-17
UniRef50_A0DWU2 Cluster: Chromosome undetermined scaffold_67, wh... 91 9e-17
UniRef50_A0CMB4 Cluster: Chromosome undetermined scaffold_21, wh... 91 9e-17
UniRef50_A0BM29 Cluster: Chromosome undetermined scaffold_115, w... 91 9e-17
UniRef50_A0BCL5 Cluster: Chromosome undetermined scaffold_10, wh... 91 9e-17
UniRef50_Q0UG58 Cluster: Putative uncharacterized protein; n=1; ... 91 9e-17
UniRef50_P25323 Cluster: Myosin light chain kinase; n=4; Dictyos... 91 9e-17
UniRef50_Q9Y6R4 Cluster: Mitogen-activated protein kinase kinase... 91 9e-17
UniRef50_P22517 Cluster: Calcium/calmodulin-dependent protein ki... 91 9e-17
UniRef50_UPI0000DB7215 Cluster: PREDICTED: similar to Stretchin-... 90 1e-16
UniRef50_UPI0000D57828 Cluster: PREDICTED: similar to CG17161-PA... 90 1e-16
UniRef50_UPI00006CF805 Cluster: Protein kinase domain containing... 90 1e-16
UniRef50_UPI00006CB430 Cluster: Protein kinase domain containing... 90 1e-16
UniRef50_UPI0000498BDB Cluster: cell division control protein 7;... 90 1e-16
UniRef50_Q4S969 Cluster: Chromosome 3 SCAF14700, whole genome sh... 90 1e-16
UniRef50_A5G0B5 Cluster: Protein kinase; n=1; Acidiphilium crypt... 90 1e-16
UniRef50_Q9M269 Cluster: Serine/threonine-protein kinase-like pr... 90 1e-16
UniRef50_Q8H643 Cluster: Calcium-dependent calmodulin-independen... 90 1e-16
UniRef50_Q9XUJ7 Cluster: Putative uncharacterized protein; n=2; ... 90 1e-16
UniRef50_Q9W179 Cluster: CG4527-PB, isoform B; n=9; Diptera|Rep:... 90 1e-16
UniRef50_Q9VL64 Cluster: CG31711-PA; n=2; Sophophora|Rep: CG3171... 90 1e-16
UniRef50_Q9NF25 Cluster: Putative uncharacterized protein; n=1; ... 90 1e-16
UniRef50_A0E1N8 Cluster: Chromosome undetermined scaffold_73, wh... 90 1e-16
UniRef50_A0CSI4 Cluster: Chromosome undetermined scaffold_26, wh... 90 1e-16
UniRef50_A0BXP1 Cluster: Chromosome undetermined scaffold_135, w... 90 1e-16
UniRef50_Q6FWK3 Cluster: Similar to sp|P27636 Saccharomyces cere... 90 1e-16
UniRef50_A7TFP9 Cluster: Putative uncharacterized protein; n=1; ... 90 1e-16
UniRef50_Q8IY84 Cluster: Serine/threonine-protein kinase NIM1; n... 90 1e-16
UniRef50_UPI000155CFAD Cluster: PREDICTED: hypothetical protein;... 90 2e-16
UniRef50_UPI000150A707 Cluster: Protein kinase domain containing... 90 2e-16
UniRef50_UPI0000DB6BB2 Cluster: PREDICTED: similar to CG8866-PA,... 90 2e-16
UniRef50_UPI0000D5577B Cluster: PREDICTED: similar to STE20-like... 90 2e-16
UniRef50_UPI000069F41E Cluster: Myosin light chain kinase, smoot... 90 2e-16
UniRef50_UPI000069DCF9 Cluster: UPI000069DCF9 related cluster; n... 90 2e-16
UniRef50_Q9XBP3 Cluster: Serine/threonine kinase PKN9; n=3; Cyst... 90 2e-16
UniRef50_Q9VW24 Cluster: CG8789-PA, isoform A; n=3; Diptera|Rep:... 90 2e-16
UniRef50_Q7QEQ2 Cluster: ENSANGP00000019856; n=1; Anopheles gamb... 90 2e-16
UniRef50_Q6BGF8 Cluster: UNC51-like kinase, putative; n=2; Param... 90 2e-16
UniRef50_Q3I4W2 Cluster: Putative serine/threonine protein kinas... 90 2e-16
UniRef50_Q23G85 Cluster: Protein kinase domain containing protei... 90 2e-16
UniRef50_Q22UZ4 Cluster: Protein kinase domain containing protei... 90 2e-16
UniRef50_A2E409 Cluster: CAMK family protein kinase; n=1; Tricho... 90 2e-16
UniRef50_A0E169 Cluster: Chromosome undetermined scaffold_72, wh... 90 2e-16
UniRef50_A0D113 Cluster: Chromosome undetermined scaffold_33, wh... 90 2e-16
UniRef50_A0CRB4 Cluster: Chromosome undetermined scaffold_25, wh... 90 2e-16
UniRef50_A0BT56 Cluster: Chromosome undetermined scaffold_126, w... 90 2e-16
UniRef50_Q5A5B8 Cluster: Likely protein kinase; n=1; Candida alb... 90 2e-16
UniRef50_O94804 Cluster: Serine/threonine-protein kinase 10; n=3... 90 2e-16
UniRef50_P38692 Cluster: Serine/threonine-protein kinase KIC1; n... 90 2e-16
UniRef50_Q13554 Cluster: Calcium/calmodulin-dependent protein ki... 90 2e-16
UniRef50_P53355 Cluster: Death-associated protein kinase 1; n=68... 90 2e-16
UniRef50_O96017 Cluster: Serine/threonine-protein kinase Chk2; n... 90 2e-16
UniRef50_UPI0000DB7219 Cluster: PREDICTED: similar to Mekk1 CG77... 89 2e-16
UniRef50_UPI0000D8A09F Cluster: myosin light chain kinase; n=1; ... 89 2e-16
UniRef50_Q5PQT0 Cluster: PAS domain containing serine/threonine ... 89 2e-16
UniRef50_Q40541 Cluster: Protein kinase; n=1; Nicotiana tabacum|... 89 2e-16
UniRef50_A7P2E2 Cluster: Chromosome chr1 scaffold_5, whole genom... 89 2e-16
UniRef50_Q4R8L8 Cluster: Testis cDNA clone: QtsA-12151, similar ... 89 2e-16
UniRef50_Q247W3 Cluster: Protein kinase domain containing protei... 89 2e-16
UniRef50_Q22T35 Cluster: Protein kinase domain containing protei... 89 2e-16
UniRef50_A3FQM1 Cluster: Putative uncharacterized protein; n=2; ... 89 2e-16
UniRef50_A0C2Z2 Cluster: Chromosome undetermined scaffold_145, w... 89 2e-16
UniRef50_Q6FKH4 Cluster: Similar to sp|P38692 Saccharomyces cere... 89 2e-16
UniRef50_Q68ST5 Cluster: P21 activated kinase-like protein; n=18... 89 2e-16
UniRef50_A5DHS1 Cluster: Putative uncharacterized protein; n=1; ... 89 2e-16
UniRef50_A3LT13 Cluster: Predicted protein; n=1; Pichia stipitis... 89 2e-16
UniRef50_Q23023 Cluster: Serine/threonine-protein kinase unc-51;... 89 2e-16
UniRef50_Q16816 Cluster: Phosphorylase b kinase gamma catalytic ... 89 2e-16
UniRef50_Q96RG2 Cluster: PAS domain-containing serine/threonine-... 89 2e-16
UniRef50_UPI0000E80B4B Cluster: PREDICTED: similar to PASK prote... 89 3e-16
UniRef50_UPI0000E46318 Cluster: PREDICTED: similar to phosphoryl... 89 3e-16
UniRef50_UPI000049A104 Cluster: protein kinase; n=1; Entamoeba h... 89 3e-16
UniRef50_UPI0000EB1271 Cluster: PAS domain-containing serine/thr... 89 3e-16
UniRef50_UPI0000ECB0D3 Cluster: PAS domain-containing serine/thr... 89 3e-16
UniRef50_Q90ZY5 Cluster: Protein kinase Chk2; n=4; Danio rerio|R... 89 3e-16
UniRef50_Q7SY52 Cluster: Zgc:63495; n=10; Euteleostomi|Rep: Zgc:... 89 3e-16
UniRef50_Q4S5N1 Cluster: Chromosome 9 SCAF14729, whole genome sh... 89 3e-16
UniRef50_A6G8X8 Cluster: Serine/threonine protein kinase; n=1; P... 89 3e-16
UniRef50_A6CBR9 Cluster: Serine/threonine protein kinase; n=1; P... 89 3e-16
UniRef50_Q10NR1 Cluster: Mitogen-activated protein kinase 1, put... 89 3e-16
UniRef50_Q6YHU9 Cluster: LOK-like protein kinase; n=3; Schistoso... 89 3e-16
UniRef50_Q4QF64 Cluster: Protein kinase, putative; n=2; Leishman... 89 3e-16
UniRef50_Q179M6 Cluster: Myosin light chain kinase; n=1; Aedes a... 89 3e-16
UniRef50_A0DFC5 Cluster: Chromosome undetermined scaffold_49, wh... 89 3e-16
UniRef50_A0DBP9 Cluster: Chromosome undetermined scaffold_44, wh... 89 3e-16
UniRef50_A0CPP6 Cluster: Chromosome undetermined scaffold_23, wh... 89 3e-16
UniRef50_A0BG19 Cluster: Chromosome undetermined scaffold_105, w... 89 3e-16
UniRef50_A5DYF0 Cluster: Calcium/calmodulin-dependent protein ki... 89 3e-16
UniRef50_Q7TSC3 Cluster: Serine/threonine-protein kinase Nek5; n... 89 3e-16
UniRef50_UPI00015B5648 Cluster: PREDICTED: similar to CG8866-PA;... 89 4e-16
UniRef50_UPI000150A8F4 Cluster: Protein kinase domain containing... 89 4e-16
UniRef50_UPI0000DB6ECE Cluster: PREDICTED: similar to loki CG108... 89 4e-16
UniRef50_UPI0000D57997 Cluster: PREDICTED: similar to CG33519-PB... 89 4e-16
UniRef50_UPI00006CAFC4 Cluster: Protein kinase domain containing... 89 4e-16
UniRef50_UPI0000498718 Cluster: protein kinase; n=1; Entamoeba h... 89 4e-16
UniRef50_UPI00002495CF Cluster: PREDICTED: similar to NUAK famil... 89 4e-16
UniRef50_Q4ST29 Cluster: Chromosome undetermined SCAF14310, whol... 89 4e-16
UniRef50_Q3B7Y1 Cluster: EG635895 protein; n=11; Mus musculus|Re... 89 4e-16
UniRef50_Q9SDM4 Cluster: Calcium-dependent protein kinase; n=2; ... 89 4e-16
UniRef50_Q8WSQ3 Cluster: Myosin light chain kinase; n=1; Physaru... 89 4e-16
UniRef50_Q8MVX2 Cluster: Putative serine/threonine protein kinas... 89 4e-16
UniRef50_Q8I6M5 Cluster: DASK1; n=9; Diptera|Rep: DASK1 - Drosop... 89 4e-16
UniRef50_Q76P07 Cluster: Similar to Dictyostelium discoideum (Sl... 89 4e-16
UniRef50_Q761W8 Cluster: Putative uncharacterized protein; n=1; ... 89 4e-16
UniRef50_Q381A7 Cluster: Mitogen activated protein kinase, putat... 89 4e-16
UniRef50_Q23DB7 Cluster: Protein kinase domain containing protei... 89 4e-16
UniRef50_A3FPS4 Cluster: OSK4, putative; n=2; Cryptosporidium|Re... 89 4e-16
UniRef50_A2FCN9 Cluster: CAMK family protein kinase; n=5; Eukary... 89 4e-16
UniRef50_A2F620 Cluster: STE family protein kinase; n=1; Trichom... 89 4e-16
UniRef50_A0DKQ6 Cluster: Chromosome undetermined scaffold_54, wh... 89 4e-16
UniRef50_A0D753 Cluster: Chromosome undetermined scaffold_4, who... 89 4e-16
UniRef50_A0CKT6 Cluster: Chromosome undetermined scaffold_20, wh... 89 4e-16
UniRef50_A0BRM8 Cluster: Chromosome undetermined scaffold_123, w... 89 4e-16
UniRef50_Q6C079 Cluster: Similar to DEHA0C13211g Debaryomyces ha... 89 4e-16
UniRef50_A7M6H7 Cluster: Calcium/calmodulin-dependent protein ki... 89 4e-16
UniRef50_A6R341 Cluster: Putative uncharacterized protein; n=1; ... 89 4e-16
UniRef50_P08458 Cluster: Sporulation-specific protein 1; n=3; Sa... 89 4e-16
UniRef50_Q9H2G2 Cluster: STE20-like serine/threonine-protein kin... 89 4e-16
UniRef50_P15735 Cluster: Phosphorylase b kinase gamma catalytic ... 89 4e-16
UniRef50_O95382 Cluster: Mitogen-activated protein kinase kinase... 89 4e-16
UniRef50_Q39030 Cluster: Serine/threonine-protein kinase AtPK19;... 89 4e-16
UniRef50_UPI000049980F Cluster: protein kinase; n=1; Entamoeba h... 88 5e-16
UniRef50_UPI0000498945 Cluster: protein kinase; n=2; Entamoeba h... 88 5e-16
UniRef50_A1A5Q6 Cluster: RGD1562638_predicted protein; n=6; Muri... 88 5e-16
UniRef50_A7PXV1 Cluster: Chromosome chr15 scaffold_37, whole gen... 88 5e-16
UniRef50_Q761X1 Cluster: Putative uncharacterized protein; n=1; ... 88 5e-16
UniRef50_Q22BC6 Cluster: Protein kinase domain containing protei... 88 5e-16
UniRef50_A7SIN7 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ... 88 5e-16
UniRef50_A0EH03 Cluster: Chromosome undetermined scaffold_96, wh... 88 5e-16
UniRef50_A0C3V8 Cluster: Chromosome undetermined scaffold_148, w... 88 5e-16
UniRef50_Q6C2G1 Cluster: Yarrowia lipolytica chromosome F of str... 88 5e-16
UniRef50_Q0UGQ2 Cluster: Putative uncharacterized protein; n=1; ... 88 5e-16
UniRef50_Q4P5N0 Cluster: Serine/threonine-protein kinase SMU1; n... 88 5e-16
UniRef50_Q7RZD3 Cluster: Serine/threonine-protein kinase ste-20;... 88 5e-16
UniRef50_Q6BNF3 Cluster: Serine/threonine-protein kinase STE20; ... 88 5e-16
UniRef50_Q8CEE6 Cluster: PAS domain-containing serine/threonine-... 88 5e-16
UniRef50_Q9P0L2 Cluster: Serine/threonine-protein kinase MARK1; ... 88 5e-16
UniRef50_UPI0001509B90 Cluster: Protein kinase domain containing... 88 6e-16
UniRef50_UPI0000F1DA2E Cluster: PREDICTED: hypothetical protein;... 88 6e-16
UniRef50_UPI0000E49CFE Cluster: PREDICTED: hypothetical protein;... 88 6e-16
UniRef50_UPI0000DA2DDE Cluster: PREDICTED: similar to MAP/microt... 88 6e-16
UniRef50_UPI00006CA70E Cluster: Protein kinase domain containing... 88 6e-16
UniRef50_Q08QR7 Cluster: Serine/threonine protein kinase; n=2; C... 88 6e-16
UniRef50_A3ZWN5 Cluster: Probable serine/threonine-protein kinas... 88 6e-16
UniRef50_A7P2X0 Cluster: Chromosome chr1 scaffold_5, whole genom... 88 6e-16
UniRef50_Q55GV3 Cluster: P21-activated protein kinase; n=2; Dict... 88 6e-16
UniRef50_Q54D55 Cluster: Autophagy protein 1; n=2; Dictyostelium... 88 6e-16
UniRef50_O61087 Cluster: NPK-1 protein kinase homolog; n=2; Tryp... 88 6e-16
UniRef50_A2GJR8 Cluster: CMGC family protein kinase; n=3; Tricho... 88 6e-16
UniRef50_A2EB11 Cluster: CAMK family protein kinase; n=3; Tricho... 88 6e-16
UniRef50_A0E8Y3 Cluster: Chromosome undetermined scaffold_83, wh... 88 6e-16
UniRef50_A0DTA2 Cluster: Chromosome undetermined scaffold_62, wh... 88 6e-16
UniRef50_A0CS98 Cluster: Chromosome undetermined scaffold_26, wh... 88 6e-16
UniRef50_A6RH99 Cluster: Putative uncharacterized protein; n=1; ... 88 6e-16
UniRef50_Q4WHP3 Cluster: Serine/threonine-protein kinase ste20; ... 88 6e-16
UniRef50_Q5SUV5 Cluster: Uncharacterized serine/threonine-protei... 88 6e-16
UniRef50_P32562 Cluster: Cell cycle serine/threonine-protein kin... 88 6e-16
UniRef50_UPI0000D55830 Cluster: PREDICTED: similar to CG1776-PA;... 87 9e-16
UniRef50_UPI00006CBD49 Cluster: Protein kinase domain containing... 87 9e-16
UniRef50_UPI00006CB772 Cluster: Protein kinase domain containing... 87 9e-16
UniRef50_UPI00006CB658 Cluster: Protein kinase domain containing... 87 9e-16
UniRef50_UPI00004990CF Cluster: protein kinase; n=1; Entamoeba h... 87 9e-16
UniRef50_UPI0000ECAF22 Cluster: Death-associated protein kinase ... 87 9e-16
UniRef50_Q4SQ82 Cluster: Chromosome 2 SCAF14534, whole genome sh... 87 9e-16
UniRef50_A6GFX5 Cluster: Serine/threonine protein kinase; n=1; P... 87 9e-16
UniRef50_Q9LQA1 Cluster: F4N2.17; n=8; Magnoliophyta|Rep: F4N2.1... 87 9e-16
UniRef50_Q10EQ9 Cluster: Protein kinase domain containing protei... 87 9e-16
UniRef50_A2XA18 Cluster: Putative uncharacterized protein; n=2; ... 87 9e-16
UniRef50_Q9W3N8 Cluster: CG17256-PA; n=2; Sophophora|Rep: CG1725... 87 9e-16
UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -... 87 9e-16
UniRef50_Q7RTG4 Cluster: Myosin light chain kinase; n=5; Plasmod... 87 9e-16
UniRef50_Q7QBZ1 Cluster: ENSANGP00000014818; n=1; Anopheles gamb... 87 9e-16
UniRef50_Q6BG60 Cluster: Protein kinase, putative; n=2; Parameci... 87 9e-16
UniRef50_Q16RU6 Cluster: Mitogen-activated protein kinase kinase... 87 9e-16
UniRef50_Q0KHT7 Cluster: CG32666-PA, isoform A; n=5; Coelomata|R... 87 9e-16
UniRef50_A5K8X1 Cluster: Rac-beta serine/threonine protein kinas... 87 9e-16
UniRef50_A0CS09 Cluster: Chromosome undetermined scaffold_26, wh... 87 9e-16
UniRef50_A0CDL3 Cluster: Chromosome undetermined scaffold_17, wh... 87 9e-16
UniRef50_Q8X1F0 Cluster: PAK1 kinase; n=3; Filobasidiella neofor... 87 9e-16
UniRef50_Q96PY6 Cluster: Serine/threonine-protein kinase Nek1; n... 87 9e-16
UniRef50_O75011 Cluster: Serine/threonine-protein kinase nak1; n... 87 9e-16
UniRef50_Q9H1R3 Cluster: Myosin light chain kinase 2, skeletal/c... 87 9e-16
UniRef50_O61661 Cluster: Serine/threonine-protein kinase grp; n=... 87 9e-16
UniRef50_UPI00015B628A Cluster: PREDICTED: similar to LD14856p; ... 87 1e-15
UniRef50_Q4SL09 Cluster: Chromosome 17 SCAF14563, whole genome s... 87 1e-15
UniRef50_Q98RL9 Cluster: SNF-related kinase; n=1; Guillardia the... 87 1e-15
>UniRef50_Q8INU8 Cluster: CG2615-PB, isoform B; n=14; Eumetazoa|Rep:
CG2615-PB, isoform B - Drosophila melanogaster (Fruit
fly)
Length = 720
Score = 620 bits (1531), Expect = e-176
Identities = 291/421 (69%), Positives = 343/421 (81%)
Query: 1 MSFLRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFE 60
MSFLRGS +YVW TTSVLGKGATG+VFQGVNK GE VAVKTFN SHMRP DVQMREFE
Sbjct: 1 MSFLRGSVSYVWCTTSVLGKGATGSVFQGVNKITGESVAVKTFNPYSHMRPADVQMREFE 60
Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
LKKV HENIVKLLAIEE+QEGRGKVIVMELCTGGSLFNILDDPEN+YGL E+EFLLVLE
Sbjct: 61 ALKKVNHENIVKLLAIEEDQEGRGKVIVMELCTGGSLFNILDDPENSYGLPEHEFLLVLE 120
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
HL AGMKHLRDN LVHRDLKPGNIMK+I+EDG T YKLTDFGAAREL++ + F SLYGTE
Sbjct: 121 HLCAGMKHLRDNKLVHRDLKPGNIMKFISEDGQTIYKLTDFGAARELEDNQPFASLYGTE 180
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
EYLHPD+YERAVLRK + +SF A VDLWSIGVTLYHVATG LPFRP+GGR+N+ETM IT
Sbjct: 181 EYLHPDLYERAVLRKSIQRSFTANVDLWSIGVTLYHVATGNLPFRPFGGRKNRETMHQIT 240
Query: 241 TKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERF 300
TKKASGVISGTQ +ENGPI+W+ LPPH LS GL+ LVTPLLAGLLE + + W+F+RF
Sbjct: 241 TKKASGVISGTQLSENGPIEWSTTLPPHAHLSQGLKTLVTPLLAGLLEENREKTWSFDRF 300
Query: 301 FSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWL 360
F EV ++ + +HVF+ N+ +S++VFL+ +E+ + + QT V E QILL+ +
Sbjct: 301 FHEVTLILRKRVIHVFFTNRTSSVEVFLEPDEQIDNFRERIFLQTEVPLEKQILLFNNEH 360
Query: 361 LTSEVNENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEPDPPKFPVFPNMVSVENDASQA 420
L +V T K++P T+ D+P+ L++ ++NNV +P + D PKFPVFP VSVENDAS A
Sbjct: 361 LEKKVTPRTIAKAFPATTTDQPIFLYSNDDNNVQLPQQLDLPKFPVFPPNVSVENDASLA 420
Query: 421 K 421
K
Sbjct: 421 K 421
Score = 48.8 bits (111), Expect = 4e-04
Identities = 32/87 (36%), Positives = 47/87 (54%), Gaps = 6/87 (6%)
Query: 442 YKVAQTVYLQTQILDKDVSAAEIKLVALTERLQDAELKIRDAVSEAKNASKTSAAVKIEA 501
YK+AQTVYL+TQIL+KDV E KL + + L + +++ V + K + + KIE
Sbjct: 621 YKLAQTVYLKTQILEKDVRDCERKLNGIRDELYHVKSELKLDV-DTKTINNNNQLAKIEE 679
Query: 502 SAEGGVPGLRALDAAHDELGAVLRHNS 528
LR + E+ AV+R NS
Sbjct: 680 RNR-----LRVMQQQQQEVMAVMRTNS 701
>UniRef50_Q4H3C0 Cluster: IkappaB kinase; n=2; Ciona
intestinalis|Rep: IkappaB kinase - Ciona intestinalis
(Transparent sea squirt)
Length = 811
Score = 483 bits (1190), Expect = e-135
Identities = 233/423 (55%), Positives = 305/423 (72%), Gaps = 4/423 (0%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHM-RPHDVQMREFEVL 62
+R + NYVWSTT +LG+GATG VF+G K G+ A+K FN L++M R + + REFEVL
Sbjct: 26 IRSTLNYVWSTTEILGQGATGFVFKGREKKTGQEYAIKVFNSLNYMARSLEARRREFEVL 85
Query: 63 KKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHL 122
+KV H+N+V+L ++EEE + VI+MELC GSL+++LDDPEN YGL E EF VL H+
Sbjct: 86 RKVDHKNVVRLFSVEEELTTKHDVIIMELCPNGSLYSMLDDPENLYGLPESEFHRVLSHI 145
Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEY 182
TAGMKHL D +VHRDLKPGNIM+ +++DGT YKLTDFGAAREL ++EQF+SLYGTEEY
Sbjct: 146 TAGMKHLHDKGIVHRDLKPGNIMRSLDDDGTAVYKLTDFGAARELGDDEQFMSLYGTEEY 205
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGG-RRNKETMFYITT 241
LHPD+YERAVLRK GK F ATVDLWS+GVTLYHVATG LPFRPYGG RRNK+ M+ ITT
Sbjct: 206 LHPDIYERAVLRKHAGKMFSATVDLWSLGVTLYHVATGMLPFRPYGGARRNKDVMYRITT 265
Query: 242 KKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFF 301
+K SGVISG Q +E G I+W+RELP C+LS G +K+ T +L+G+LE +PH+IWTF+R+F
Sbjct: 266 EKPSGVISGVQHSERGSIEWSRELPKTCRLSHGFKKIFTVVLSGILECNPHKIWTFDRYF 325
Query: 302 SEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLL 361
+EV+ + S K ++VF V A KV++ E+ V E T V + Q+LL+
Sbjct: 326 AEVEDILSKKVINVFSVPNAMLHKVYISPEKTLVSFQEAVAELTEVRSSKQLLLFDGEQF 385
Query: 362 TSEVNENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEPDPPKFPVFPNMVSVENDASQAK 421
E+ + P KSYP T+ + PL+LF+ + N+ P K P +S++ND+S AK
Sbjct: 386 --EMEQFVPVKSYPHTTPEHPLILFSSDINDFQAITIPHTCKPPKVKPSLSLDNDSSLAK 443
Query: 422 VSS 424
V S
Sbjct: 444 VCS 446
>UniRef50_Q9UHD2 Cluster: Serine/threonine-protein kinase TBK1;
n=22; Euteleostomi|Rep: Serine/threonine-protein kinase
TBK1 - Homo sapiens (Human)
Length = 729
Score = 440 bits (1084), Expect = e-122
Identities = 214/425 (50%), Positives = 288/425 (67%), Gaps = 8/425 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + N++W + +LG+GAT VF+G +K G+ A+K FN +S +RP DVQMREFEVLK
Sbjct: 1 MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK 60
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL AIEEE R KV++ME C GSL+ +L++P N YGL E EFL+VL +
Sbjct: 61 KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV 120
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
GM HLR+N +VHRD+KPGNIM+ I EDG + YKLTDFGAAREL+++EQFVSLYGTEEYL
Sbjct: 121 GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL 180
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPY-GGRRNKETMFYITTK 242
HPDMYERAVLRK K +GATVDLWSIGVT YH ATG LPFRP+ G RRNKE M+ I T
Sbjct: 181 HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG 240
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFS 302
K SG ISG Q ENGPIDW+ ++P C LS GL+ L+TP+LA +LE D + W F++FF+
Sbjct: 241 KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA 300
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLT 362
E + +HVF + + T+ K+++ H V +QT +++ +Q L+Y+ L
Sbjct: 301 ETSDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLV 360
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKNN-NNVSMPAEP-DPPKFPVFPNMVSVENDASQA 420
E + +P T+ + P+ + ++ N + + E PK V P ++ DAS A
Sbjct: 361 LE--PGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPK--VHPR-YDLDGDASMA 415
Query: 421 KVSSG 425
K +G
Sbjct: 416 KAITG 420
>UniRef50_Q14164 Cluster: Inhibitor of nuclear factor kappa-B kinase
subunit epsilon; n=23; Tetrapoda|Rep: Inhibitor of
nuclear factor kappa-B kinase subunit epsilon - Homo
sapiens (Human)
Length = 716
Score = 427 bits (1053), Expect = e-118
Identities = 213/426 (50%), Positives = 287/426 (67%), Gaps = 8/426 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + NY+W T +LG+GAT +V++ NK +GE VAVK FN S++RP +VQ+REFEVL+
Sbjct: 1 MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR 60
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL A+EE R KV+VME C+ GSL ++L+ PEN +GL E EFL+VL +
Sbjct: 61 KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV 120
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
AGM HLR+N +VHRD+KPGNIM+ + E+G + YKLTDFGAAREL ++E+FVS+YGTEEYL
Sbjct: 121 AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL 180
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGG-RRNKETMFYITTK 242
HPDMYERAVLRKP K+FG TVDLWSIGVTLYH ATG LPF P+GG RRNKE M+ ITT+
Sbjct: 181 HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE 240
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFS 302
K +G I+G Q ENGP++W+ LP CQLS+GL+ + P+LA +LEV+ + W F++FF+
Sbjct: 241 KPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFA 300
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLT 362
E + VHVF +++A +++ V +QTSV Q L++ L
Sbjct: 301 ETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCV 360
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEP--DPPKFPVFPNMVSVENDASQA 420
E + + T+A PL LF+ +P D PKF P V ++ D + A
Sbjct: 361 LE--PSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKF--VPK-VDLQADYNTA 415
Query: 421 KVSSGA 426
K GA
Sbjct: 416 KGVLGA 421
>UniRef50_Q6DGE5 Cluster: Zgc:100844; n=3; Danio rerio|Rep:
Zgc:100844 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 721
Score = 407 bits (1001), Expect = e-112
Identities = 193/406 (47%), Positives = 277/406 (68%), Gaps = 6/406 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
+ + NY+WS +LG+GAT V++ NK GE VAVK FN +S+ RP++VQMREFEVL+
Sbjct: 1 MTSTANYLWSQEDILGQGATANVYKARNKKTGELVAVKVFNLVSYNRPYEVQMREFEVLQ 60
Query: 64 KVKHENIVKLLAIEEE-QEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHL 122
+ H NIVKL A+EE + K++VME C+GGSL N+L+ PE+ +GL E EFL+VL +
Sbjct: 61 LLNHVNIVKLFAVEEIISNPKQKILVMEYCSGGSLLNMLEQPEHAFGLPESEFLIVLHCV 120
Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEY 182
GM HLR+N++VHRD+KPGNIM+ + EDG + YKL DFGAAREL+++E+FVS+YGTEEY
Sbjct: 121 AHGMNHLRENSVVHRDIKPGNIMRQVGEDGRSVYKLADFGAARELEDDEKFVSIYGTEEY 180
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGG-RRNKETMFYITT 241
LHPDMYERAVLR P K++G +VDLWSIGVT+YH+ATG LPFRP+GG R+NK+ M ITT
Sbjct: 181 LHPDMYERAVLRSPQQKAYGVSVDLWSIGVTIYHMATGSLPFRPFGGPRKNKQMMHKITT 240
Query: 242 KKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFF 301
+K +G I+G Q E+GPI+W +LP CQLS GL+ + P+LA +L D + W F +FF
Sbjct: 241 EKPAGTIAGVQKEEDGPIEWRDKLPLSCQLSEGLKTQLVPVLANILLADDEKCWKFPQFF 300
Query: 302 SEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLL 361
S + + +++F + +AT+ ++++ V QT + +Q L++ L
Sbjct: 301 SATNDILNRITIYIFSLQQATTYSIYIQFHNTVSIFFEDVQAQTGIEPAAQQYLFQGHPL 360
Query: 362 TSEVNENTPGKSYPDTSADEPLLLFNKN-NNNVSMP-AEPDPPKFP 405
++ + + P TS+D+P++L ++ + P EP+ P P
Sbjct: 361 I--LDPSMKVVNIPHTSSDKPMILISRRLERIIGYPFEEPESPPMP 404
>UniRef50_Q4SRA2 Cluster: Chromosome 11 SCAF14528, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 11 SCAF14528, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 785
Score = 397 bits (977), Expect = e-109
Identities = 200/407 (49%), Positives = 273/407 (67%), Gaps = 17/407 (4%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
NY+WS VLG+GAT V++ NK +GE VAVK FN +S+ RPHDVQMREFE+L+K+ H
Sbjct: 10 NYLWSLQDVLGQGATANVYKARNKKSGELVAVKVFNTVSYNRPHDVQMREFEMLRKLNHS 69
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
NIV+L A+EE + KV+VME C+GGSL +L++PEN +GL E EFL VL+ + GM H
Sbjct: 70 NIVRLYAVEE-LPSKQKVLVMEYCSGGSLLMLLEEPENAFGLPETEFLTVLQCVVRGMNH 128
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMY 188
LR+N +VHRD+KPGNIM+ EDG + YKLTDFGAAREL+++E+F+S+YGTEEYLHPDMY
Sbjct: 129 LRENGVVHRDIKPGNIMRQTGEDGKSVYKLTDFGAARELEDDEKFISIYGTEEYLHPDMY 188
Query: 189 ERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGG-RRNKETMFYITTKKASGV 247
+ AVLRKP KS+G +VDLWSIGVT YH ATG LPF P+GG R+NK TMF ITT+K +G
Sbjct: 189 KCAVLRKPHQKSYGVSVDLWSIGVTFYHAATGSLPFVPFGGPRKNKLTMFKITTEKPTGA 248
Query: 248 ISGTQTTENGPIDWARELPPHCQLS----VGLRKLVTPLLAGLLEVDPHRIWTFERFFSE 303
ISGTQ +G I+W LP CQLS GL+ + P+LAG++E D + W F++FF+
Sbjct: 249 ISGTQHVVDGSIEWGYNLPHSCQLSQYVGTGLKAQLVPVLAGIMEADQEKCWGFDQFFTA 308
Query: 304 VQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYK-DWLLT 362
+ +PVH+F + +A + +++ Y H+ + V ++ L+K D
Sbjct: 309 TTDILQRQPVHLFSLQQAMAHCIYI---HHYDTRHS--GDPAQVRCSGRLQLHKGDGGSG 363
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKN-----NNNVSMPAEPDPPKF 404
+ V + PG + P +A LL + + N V +P++ P F
Sbjct: 364 APVPDEHPGAALPQRAAPAGLLQLHVSHTQAPNQGVPLPSDLVSPTF 410
>UniRef50_UPI0000E4740B Cluster: PREDICTED: similar to IkappaB
kinase, partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to IkappaB kinase, partial -
Strongylocentrotus purpuratus
Length = 479
Score = 390 bits (959), Expect = e-107
Identities = 198/423 (46%), Positives = 274/423 (64%), Gaps = 10/423 (2%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
+R + Y+ + LG+GAT V+ G +K G+ VA K + + R RE +VL
Sbjct: 31 IRSTPGYIIFLDTPLGQGATSKVYGGRHKKLGKRVACKVPHTANLFRMGTDMERESQVLL 90
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
+++++NIV L AIE++Q + +++MELCTGGSL+++L+ PEN+ GL E FL VL +T
Sbjct: 91 RLRNQNIVCLEAIEKDQISKENILIMELCTGGSLYDVLEKPENSCGLAEKAFLQVLADMT 150
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
AGMK+LRDN +VHRD+KPGNIM + ++ G T YKL DFGAAR+L ++E F SL+GTEEYL
Sbjct: 151 AGMKYLRDNGVVHRDVKPGNIMCFKDDHGHTIYKLADFGAARQLTDDENFTSLHGTEEYL 210
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
HP ++ERAVLRKP F A +DLWSIG TLYH+ATGQLPFRP+GGR+N MF++TTKK
Sbjct: 211 HPKVFERAVLRKPAALPFDARIDLWSIGATLYHLATGQLPFRPHGGRKNSRMMFHLTTKK 270
Query: 244 ASGVISGTQTTENGPID----WARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFER 299
A GVISG QT GP+D W+RELP C+LS+GL+KL+TPLLAGLLE +P +W+F+
Sbjct: 271 APGVISGVQT---GPLDHEITWSRELPETCRLSIGLKKLITPLLAGLLESNPSTVWSFQH 327
Query: 300 FFSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDW 359
FF Q +T+ + VF+V +A+ +K++ +++ + QT + A Q +LY
Sbjct: 328 FFQASQAITTKIAIDVFWVCEASYMKIYCSPTDRFAEFQENIASQTKLSATKQSILYNG- 386
Query: 360 LLTSEVNENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEPD-PPKFPVFPNMVSVENDAS 418
T + + P SYP TS P+ L NK +V P P S +ND
Sbjct: 387 -ETFKPDGILPISSYPITSVANPITLSNKEQIHVQHQLTPPFVATMPALRPRFSTQNDYP 445
Query: 419 QAK 421
AK
Sbjct: 446 IAK 448
>UniRef50_UPI0000E4A8B8 Cluster: PREDICTED: similar to IkappaB
kinase; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to IkappaB kinase -
Strongylocentrotus purpuratus
Length = 762
Score = 376 bits (926), Expect = e-103
Identities = 203/456 (44%), Positives = 263/456 (57%), Gaps = 2/456 (0%)
Query: 26 VFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIEEEQEGRGK 85
V Q N NG+ VAVK FN LS+MRP DVQ REFEVL K+ H+NI+ L IEE+Q +
Sbjct: 5 VTQVRNGKNGDVVAVKMFNHLSYMRPRDVQQREFEVLLKLNHKNIIHLDQIEEDQISKQP 64
Query: 86 VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIM 145
VIVMELCTGGSL+ LD PEN YGL+E EFL VL ++AGMKHLRD +VHRD+KPGNIM
Sbjct: 65 VIVMELCTGGSLYTYLDTPENLYGLKEKEFLQVLNDVSAGMKHLRDKGIVHRDIKPGNIM 124
Query: 146 KYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATV 205
EDG YKL DFGAAREL+++E F SLYGTEEYLHPD+YERAVL K F A
Sbjct: 125 MVKGEDGVIVYKLADFGAARELEDDEAFKSLYGTEEYLHPDLYERAVLGKRNRTEFTAQT 184
Query: 206 DLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGVISGTQTTENGPIDWAREL 265
DLWS+GVT +H ATG LPFR +GGR N+E M ITT K S +ISG Q NGPI W+ +L
Sbjct: 185 DLWSLGVTFFHTATGSLPFRAHGGRNNREVMHNITTTKKSSMISGVQEVPNGPIIWSEDL 244
Query: 266 PPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFSEVQVVTSTKPVHVFYVNKATSIK 325
P C S +R V LL+ +E + ++WTF+ FF VQ +TS +PV VF
Sbjct: 245 PKTCHFSPDMRHQVKTLLSHTMECNIQKMWTFDIFFDFVQRLTSMRPVDVFVAPTCECHI 304
Query: 326 VFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLTSEVNENTPGKSYPDTSADEPLLL 385
++++ + K + T + ++Q LL+ + ++ + + P TS D PL+L
Sbjct: 305 IYVEPQRKVVDFQDKMAHLTGIQPDTQSLLWDKEVF--DLKKCLKCEDLPQTSPDNPLIL 362
Query: 386 FNKNNNNVSMPAEPDPPKFPVFPNMVSVENDASQAKVSSGAKTARPALDRSMSSRRYKVA 445
P P P SV+ D++ AK S + S++ +
Sbjct: 363 VRMGAEVFPSVKVPSLPTQPKTATHFSVQQDSTLAKNCSAVMCYYVNVVGSLARIETLIT 422
Query: 446 QTVYLQTQILDKDVSAAEIKLVALTERLQDAELKIR 481
QTV +L D K A+ A+ + R
Sbjct: 423 QTVKAVVVVLRMDYMKLRSKHSAVKSSCLQADCRWR 458
>UniRef50_UPI0000E1EF55 Cluster: PREDICTED: IKK-related kinase
epsilon; n=1; Pan troglodytes|Rep: PREDICTED:
IKK-related kinase epsilon - Pan troglodytes
Length = 752
Score = 340 bits (836), Expect = 5e-92
Identities = 166/292 (56%), Positives = 212/292 (72%), Gaps = 26/292 (8%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + NY+W T +LG+GAT +V++ NK +GE VAVK FN S++RP +VQ+REFEVL+
Sbjct: 1 MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR 60
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL A Q KV+VME C+ GSL ++L+ PEN +GL E EFL+VL +
Sbjct: 61 KLNHQNIVKLFAGGSRQ----KVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV 116
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
AGM HLR+N +VHRD+KPGNIM+ + E+G + YKLTDFGAAREL ++E+FVS+YGTEEYL
Sbjct: 117 AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL 176
Query: 184 ---------------------HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQL 222
HPDMYERAVLRKP K+FG TVDLWSIGVTLYH ATG L
Sbjct: 177 ELCLSPVPQPEECILFSEMEKHPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSL 236
Query: 223 PFRPYGG-RRNKETMFYITTKKASGVISGTQTTENGPIDWARELPPHCQLSV 273
PF P+GG RRNKE M+ ITT+K +G I+G Q ENGP++W+ LP CQLS+
Sbjct: 237 PFIPFGGPRRNKEIMYRITTEKPAGAIAGAQRRENGPLEWSYTLPITCQLSL 288
>UniRef50_Q4TD09 Cluster: Chromosome undetermined SCAF6590, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF6590,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 229
Score = 252 bits (618), Expect = 1e-65
Identities = 127/229 (55%), Positives = 160/229 (69%), Gaps = 21/229 (9%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + NY+W + +LG+GAT V++G +K G+ AVK FN LS +RP DVQMREFEVLK
Sbjct: 1 MQSTTNYLWLISDLLGQGATANVYRGRHKKTGDLYAVKVFNNLSFLRPLDVQMREFEVLK 60
Query: 64 KVKHENIVKLLAIEEE-------QEGRGKVIVMEL--------------CTGGSLFNILD 102
K+ H+NIVKL A+EEE + G ++ L GSL+ +L+
Sbjct: 61 KLNHKNIVKLFAVEEEVGSCRSCRSHSGAALIRVLFAVQHPPQGPGDGVLVCGSLYTVLE 120
Query: 103 DPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFG 162
+ TYGL E EFL+VL + AGM HLR+ +VHRD+KPGNIM+ I EDG + YKLTDFG
Sbjct: 121 ESSQTYGLPEDEFLIVLHDVVAGMNHLREYGIVHRDIKPGNIMRVIGEDGRSVYKLTDFG 180
Query: 163 AARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIG 211
AAREL+++EQFVSLYGTEEYLHPDMYERAVLRK K +GATVDLWSIG
Sbjct: 181 AARELEDDEQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSIG 229
>UniRef50_UPI000065D755 Cluster: SPFH domain-containing protein 1
precursor (Protein KE04).; n=1; Takifugu rubripes|Rep:
SPFH domain-containing protein 1 precursor (Protein
KE04). - Takifugu rubripes
Length = 721
Score = 135 bits (326), Expect = 3e-30
Identities = 118/406 (29%), Positives = 183/406 (45%), Gaps = 31/406 (7%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG G G V+ + +GE +AVK + + + RE +++KK+KH N+V
Sbjct: 15 WEMKERLGMGGFGHVYLYQHLESGEKMAVKLCRLELNSKNKERWSREIQIMKKLKHGNVV 74
Query: 72 KLLAIEEEQEGRG----KVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
+ + EE ++ ME C+ G L +L+ PEN GL+E E +L + +G++
Sbjct: 75 QAREVPEELTSISLNDLPLLAMEYCSRGDLRKLLNKPENCCGLKESEVFSLLSDIGSGVQ 134
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
+L DN ++HRD+KP NI+ DG +KL D G A++L + S GT +YL P++
Sbjct: 135 YLHDNKIIHRDIKPENIVLQ-EVDGKLVHKLIDLGYAKDLDQGSLCTSFVGTIQYLAPEL 193
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGV 247
+E K + TVD WS G ++ G FRP+ K
Sbjct: 194 FE--------NKPYTVTVDYWSFGTVIFECICG---FRPFLHHMQPVQWTSKVKNKGPKD 242
Query: 248 ISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDP-HRIWTFERFFSE--- 303
I T+ NG + ++ L LS L + V LL LL DP R T + ++
Sbjct: 243 IMATEDM-NGEVRFSAHLHYPNNLSRPLLEPVESLLQMLLLWDPAARGGTVDADTNKPYC 301
Query: 304 ---VQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTS--VVAESQILLYKD 358
+Q + + K +HV + A + L EE LH + QT + SQ LL +
Sbjct: 302 NTALQNILNLKVIHVLDMTSAQLHSLILGAEENLQSLHLRLEAQTQSHIPPLSQELLLET 361
Query: 359 WLLTSEVNENTPGKSYPD--TSADEPLL-LFNKNNNNVSMPAEPDP 401
+ S P + PD D ++ LF+K+ N S P P
Sbjct: 362 GV--SLDPRRPPSQCLPDGLQGCDSCIVFLFDKSLNKYSGPLTARP 405
>UniRef50_Q2VU38 Cluster: IKK-like protein; n=4; Coelomata|Rep:
IKK-like protein - Pinctada fucata (Pearl oyster)
Length = 737
Score = 130 bits (313), Expect = 1e-28
Identities = 68/220 (30%), Positives = 117/220 (53%), Gaps = 13/220 (5%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHM-RPHDVQMR-EFEVLKKVKHEN 69
W +LG G G V +++N + +A+KT + M H + + E +++K++ H N
Sbjct: 9 WIQDRILGSGGFGQVVLWKHEDNDQYIAIKTCRVQNEMTEKHKQRWKLEVDIMKRLDHTN 68
Query: 70 IVKLLAIE---EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
++ + E E ++ ME C+GG L +L+ PE+ GL+EYE +++ +++ +
Sbjct: 69 VIAARDVPPPLEVTENELPLLAMEYCSGGDLRKVLNLPESACGLKEYEIRNLVKDISSAI 128
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPD 186
++L ++HRDLKP N++ +ED T YKL D G A+EL + S GT +YL P+
Sbjct: 129 EYLHGKRIIHRDLKPENVVLTQSEDNKTVYKLIDLGYAKELDQSSVCTSFVGTLQYLAPE 188
Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRP 226
++ + + TVD WS G ++ TG PF P
Sbjct: 189 LF--------ASQKYTCTVDYWSFGTVVFECITGYRPFLP 220
>UniRef50_Q294U5 Cluster: GA18025-PA; n=1; Drosophila
pseudoobscura|Rep: GA18025-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 713
Score = 123 bits (297), Expect = 1e-26
Identities = 76/240 (31%), Positives = 117/240 (48%), Gaps = 27/240 (11%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHM------RPHDVQMREFEVLKKV 65
W LG+G G V +N N G+ +A K +S + + + M+E E + +
Sbjct: 8 WQLKGKLGQGGFGEVLHWLNSNTGQQIATKHIKDVSSLGADQQVKLKERWMKELEWTRSI 67
Query: 66 -KHENIVKLLAIEEEQEG-----------RGKVIVMELCTGGSLFNILDDPENTYGLQEY 113
K NIV + ++ E + VI++E C GG + +L PEN GL E+
Sbjct: 68 QKLTNIVAGVCLKNEDASFVAYLNKNHICQLPVIILEYCNGGDVRQLLQRPENANGLAEF 127
Query: 114 EFLLVLEHLTAGMKHLRDN-NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ 172
E +L L ++ L + HRDLKP NI+ + DG+ TYKLTDFG AR ++
Sbjct: 128 EVRQILRDLAQALQFLHSECKVCHRDLKPDNIVIHRQTDGSKTYKLTDFGLARGAPDQTI 187
Query: 173 FVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRN 232
S+ GT Y P++ + + + VD WS+G+ Y +ATG++PF P+ RN
Sbjct: 188 LQSMVGTRHYFAPEVVDTGM--------YNTAVDYWSLGIIAYELATGEVPFIPHQTPRN 239
>UniRef50_O15111 Cluster: Inhibitor of nuclear factor kappa-B kinase
subunit alpha; n=40; Euteleostomi|Rep: Inhibitor of
nuclear factor kappa-B kinase subunit alpha - Homo
sapiens (Human)
Length = 745
Score = 121 bits (291), Expect = 6e-26
Identities = 95/362 (26%), Positives = 161/362 (44%), Gaps = 23/362 (6%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
LR W LG G G V ++ +A+K+ + + E +++K
Sbjct: 7 LRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMK 66
Query: 64 KVKHENIVKLLAIEEEQE---GRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
K+ H N+VK + EE ++ ME C+GG L +L+ PEN GL+E + L +L
Sbjct: 67 KLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLS 126
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +G+++L +N ++HRDLKP NI+ + G +K+ D G A+++ + S GT
Sbjct: 127 DIGSGIRYLHENKIIHRDLKPENIVLQ-DVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTL 185
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
+YL P+++E K + ATVD WS G ++ G +RP+ T
Sbjct: 186 QYLAPELFE--------NKPYTATVDYWSFGTMVFECIAG---YRPFLHHLQPFTWHEKI 234
Query: 241 TKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHR------- 293
KK I + +G + ++ LP L + + + L +L DP +
Sbjct: 235 KKKDPKCIFACEEM-SGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRGGPVDL 293
Query: 294 IWTFERFFSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQI 353
R F + + + K VH+ + A I L +E L + + +T + SQ
Sbjct: 294 TLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQE 353
Query: 354 LL 355
LL
Sbjct: 354 LL 355
>UniRef50_O14920 Cluster: Inhibitor of nuclear factor kappa-B kinase
subunit beta; n=34; Euteleostomi|Rep: Inhibitor of
nuclear factor kappa-B kinase subunit beta - Homo
sapiens (Human)
Length = 756
Score = 120 bits (290), Expect = 7e-26
Identities = 91/353 (25%), Positives = 154/353 (43%), Gaps = 22/353 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG G G V + N+ GE +A+K Q R + E ++++++ H N+V
Sbjct: 15 WEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVV 74
Query: 72 KLLAIEEEQEGRGK----VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
+ E + ++ ME C GG L L+ EN GL+E L +L + + ++
Sbjct: 75 AARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALR 134
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
+L +N ++HRDLKP NI+ E +K+ D G A+EL + S GT +YL P++
Sbjct: 135 YLHENRIIHRDLKPENIVLQQGEQ-RLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPEL 193
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGV 247
E+ + + TVD WS G + TG PF P + ++ ++ S V
Sbjct: 194 LEQ--------QKYTVTVDYWSFGTLAFECITGFRPFLP----NWQPVQWHSKVRQKSEV 241
Query: 248 ISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERF-----FS 302
NG + ++ LP L+ L + + L +L P + T + F
Sbjct: 242 DIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFK 301
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILL 355
+ + + K VH+ + T + +E L + + T + E Q LL
Sbjct: 302 ALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELL 354
>UniRef50_UPI000150A1D4 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 907
Score = 119 bits (286), Expect = 2e-25
Identities = 79/221 (35%), Positives = 119/221 (53%), Gaps = 23/221 (10%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR---EFEVLKKV 65
NY WS LGKGA G+VF+G N GE VAVK Q+ H + +++ E V+KK+
Sbjct: 12 NYQWSEQDFLGKGAFGSVFKGKNIETGEQVAVKVL-QMQHFKNEQAKIQLDEEINVMKKL 70
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
IVKLL ++EE E VI++ELC G L N+L + L E E + +L L G
Sbjct: 71 DSPYIVKLLGLQEENE--QTVIILELCPEGDLNNLLKSKGGS--LNEQEAINILCQLLLG 126
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAR--ELQEEEQFVSLYGTEEYL 183
K + + +HRD+KP NI + +DG YK++DFG A +++ ++ GT ++
Sbjct: 127 FKKMVEQGYIHRDIKPANI---LIKDG--FYKVSDFGFATGVDIKSQQLLKECVGTPLFM 181
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P + LR K + + D+WSIG+ Y + G+ P+
Sbjct: 182 APQL-----LR---SKEYSSKSDIWSIGMMYYLMLFGKTPW 214
>UniRef50_Q22LY2 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 803
Score = 119 bits (286), Expect = 2e-25
Identities = 77/240 (32%), Positives = 123/240 (51%), Gaps = 25/240 (10%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ---MREFEVLKK 64
+NY ++T +G+G+ G VF+G++ E +A+KT +Q +Q M E E+LK+
Sbjct: 13 KNYQYNTRHCIGEGSYGKVFEGIDVKTQEKIAIKTIDQNIFKNDQYLQCAIMAEIEILKR 72
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
H+NIVK I E + I+ E C G L + +N L E + + +
Sbjct: 73 FDHKNIVKFKDIVYEDD--TIYIITEFCQDGDLRQFMKSNKN---LSEDVITQIFKQILE 127
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL--QEEEQFVSLYGTEEY 182
G++ L ++HRDLKP NI+ + NE +K+ DFG AR++ Q E+ VS G+ Y
Sbjct: 128 GIRELHKVGVIHRDLKPANILIHNNE-----FKIADFGFARDVDFQSEKLLVSCVGSPMY 182
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTK 242
+ P + R K +G D+WS+GV LY + G+ P+ + R +E + I TK
Sbjct: 183 MDPLILSR--------KPYGTKCDIWSLGVILYEMIMGETPY--HKSRTEQELLINIYTK 232
>UniRef50_UPI0000519C1C Cluster: PREDICTED: similar to Inhibitor of
nuclear factor kappa B kinase subunit beta
(I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B)
(I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B
inhibitor kinase beta) (NFKBIKB) isoform 2; n=1; Apis
mellifera|Rep: PREDICTED: similar to Inhibitor of
nuclear factor kappa B kinase subunit beta
(I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B)
(I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B
inhibitor kinase beta) (NFKBIKB) isoform 2 - Apis
mellifera
Length = 232
Score = 116 bits (279), Expect = 2e-24
Identities = 71/221 (32%), Positives = 118/221 (53%), Gaps = 16/221 (7%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ-LSHMRPHDVQ--MREFEVLKKVKHE 68
W+ VLG G G V +KN G+ +A+K + + H+ + + E ++K++KH
Sbjct: 11 WTLDKVLGSGGFGIVQLWTHKN-GKKIAIKICKKDVIHLTETQQKRWINEINIMKRLKHP 69
Query: 69 NIVKLLAIEEEQEGRGK---VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
NIVK + + K ++ ME C G L ++L EN G+ E E + V++ +++
Sbjct: 70 NIVKGFDLPFKHPDDKKDLPILCMEFCRKGDLRSLLKKVENCCGVSEKEAINVMKDISSA 129
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
+++L NN+ HRDLKP NI+ +E +YKL D G A+EL E SL GT Y+ P
Sbjct: 130 IEYLHSNNITHRDLKPENIVLQ-DERNIISYKLIDLGFAKELGEASISGSLVGTLNYVAP 188
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRP 226
++ + +++ +VD WS+G+ Y + +G PF P
Sbjct: 189 ELLWK--------QTYSCSVDYWSLGILFYELVSGIRPFLP 221
>UniRef50_UPI0000E46D98 Cluster: PREDICTED: similar to doublecortin
and CaM kinase-like 3; n=6; Deuterostomia|Rep:
PREDICTED: similar to doublecortin and CaM kinase-like 3
- Strongylocentrotus purpuratus
Length = 991
Score = 115 bits (276), Expect = 4e-24
Identities = 75/233 (32%), Positives = 118/233 (50%), Gaps = 19/233 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V + K G+ A+K + + E ++K V+H NIV+L
Sbjct: 701 IGDGNFADVHEATQKKTGDEFALKVIEKAKVKNKEHMVENEIAIMKHVRHPNIVRLY--- 757
Query: 78 EEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
EE E RG + +VME TGG LF+ + + + E + L++ L +K+L D N+VH
Sbjct: 758 EEYETRGHIYLVMEYVTGGDLFDAITE---SVKFTERDAALMVTDLAKALKYLHDLNVVH 814
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP N++ +E G T KL DFG A E+ +E ++ GT Y+ P++
Sbjct: 815 RDLKPENLLVNKSESGEITLKLADFGLAMEV--KEPIYTVCGTPTYVAPEILGE------ 866
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGVIS 249
K +G VD+W+IGV Y + G PFR R++E +F + + A ++
Sbjct: 867 --KGYGLEVDMWAIGVITYILLCGFPPFR--SPDRDQEELFELIQEGAFSFVA 915
>UniRef50_Q23R88 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1766
Score = 115 bits (276), Expect = 4e-24
Identities = 71/221 (32%), Positives = 126/221 (57%), Gaps = 22/221 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKV 65
ENY +S ++ +GKG++G V+ G ++ + VA+K + S + +M E +++KK+
Sbjct: 14 ENYAFSLSACIGKGSSGTVYVGRHQQTQQVVAIKAVDMRSLKTEYAWKMLCSEVKIMKKL 73
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
KH ++V+LL + + + I+ E C G L L ++ L E E + V+ + +G
Sbjct: 74 KHPHVVRLLDVFQTKNNT--YIITEFCNQGDLRTYLKKKKS---LTEREAITVISQIMSG 128
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL--QEEEQFVSLYGTEEYL 183
++ L +N ++HRDLKP NI+ I++D +K+TDFG A++L E++ SL GT Y+
Sbjct: 129 LQELANNGIIHRDLKPANIL--IHDD---VFKITDFGFAKKLDSMEDQLMDSLVGTPLYM 183
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P +L K + + + D+WSIG+ LY + G+ P+
Sbjct: 184 APQ-----ILNK---QQYTSKCDVWSIGLILYELLFGRTPW 216
>UniRef50_Q4RSR9 Cluster: Chromosome 12 SCAF14999, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 12 SCAF14999, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 673
Score = 114 bits (274), Expect = 6e-24
Identities = 96/359 (26%), Positives = 159/359 (44%), Gaps = 30/359 (8%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENI 70
+W LG G G V + NK E +A+K Q R + E E++K++ H N+
Sbjct: 16 LWELRERLGNGGFGNVTRWQNKETEEQIAIKQCRQELSERNKERWCLEIEIIKRLDHVNV 75
Query: 71 VKLLAIEEEQEGRGKV--------IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHL 122
V A E EG K+ + ME C GG L L+ EN G++E L++L +
Sbjct: 76 V---AAREVPEGMQKLMAINDLPLLAMEYCQGGDLRKYLNLLENCCGMREGSVLILLCDI 132
Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEY 182
++ + +L ++HRDLKP NI+ E +K+ D G A++L VS GT +Y
Sbjct: 133 SSALSYLHKKRIIHRDLKPENIVLQQGEK-RLIHKIIDLGYAKQLDHSSLCVSFVGTLQY 191
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTK 242
L P++ ER + + TVD WS G ++ TG PF P + + K
Sbjct: 192 LAPELIER--------QKYTVTVDYWSFGTLVFECITGFRPFLP--SWQPVPWHHKVRLK 241
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFER--- 299
+ ++ T G + + + LP L+ L + L +L+ P
Sbjct: 242 GNNDIVVYEDLT--GEVHYCKHLPQPNNLNSLLSGKLERWLQLMLKWSPQERGKDPEAAP 299
Query: 300 --FFSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSV-VAESQILL 355
FS+++++ K VHV + A + + +E L + T++ VA+ ++LL
Sbjct: 300 NDCFSQLRLILQLKLVHVLNMMSAKILSYSVSEDETVADLQLRIEADTNIPVAKQELLL 358
>UniRef50_UPI0000D57829 Cluster: PREDICTED: similar to inhibitor of
kappaB kinase beta; n=2; Tribolium castaneum|Rep:
PREDICTED: similar to inhibitor of kappaB kinase beta -
Tribolium castaneum
Length = 756
Score = 113 bits (273), Expect = 9e-24
Identities = 100/362 (27%), Positives = 158/362 (43%), Gaps = 32/362 (8%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKT--FNQLSHMRPHDVQM--REFEVLKKVKH 67
W S+LG GA G V + +G+ +A+K F H+ Q E +++K +
Sbjct: 62 WKRISILGSGAFGVVALWQHAGSGDYIAIKKCKFRTSGHLSDRQKQRWENEVQIMKTLNC 121
Query: 68 ENIVKLLAIEEEQEG--------RGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVL 119
NIV + E R ++ ME C G+L ++L+ +N+ GL E + VL
Sbjct: 122 PNIVSFKLLPPHLEAVLLKYNPTRLPLLSMEYCRKGNLRHVLNQAKNSSGLGESDVRTVL 181
Query: 120 EHLTAGMKHLRDNNLVHRDLKPGNI-MKYIN-EDGTTTYKLTDFGAARELQEEEQFVSLY 177
+T + +L N+ HRD+KP NI +++ N G YKL D G A+EL + VS
Sbjct: 182 ADVTQAVSYLHKQNITHRDIKPENIVLQHCNTRPGDVIYKLIDLGYAKEL--SDSVVSFV 239
Query: 178 GTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
GT YL P++ + +++ +VD WS+GV + V G LPF P E
Sbjct: 240 GTLHYLAPEIMKT--------ENYDFSVDYWSLGVVAFEVICGVLPFLPL--YTPMERFS 289
Query: 238 YITTKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDP-HRIWT 296
+I KK + +G + ++ EL +S L++ + L +L+ DP R
Sbjct: 290 FIERKKPEHIC--IYQLHSGSVMYSSELLKENHISTCLKQNIESWLRHVLQFDPTQRRAN 347
Query: 297 F---ERFFSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQI 353
F F + + K V VF V+ + L ++ T V QI
Sbjct: 348 FPDNSNVFDCLLNILDKKIVTVFSVHTLEFYSYEINESILISTLKDWIARDTKVQKSDQI 407
Query: 354 LL 355
LL
Sbjct: 408 LL 409
>UniRef50_Q229U9 Cluster: Protein kinase domain containing protein;
n=4; Oligohymenophorea|Rep: Protein kinase domain
containing protein - Tetrahymena thermophila SB210
Length = 493
Score = 111 bits (268), Expect = 3e-23
Identities = 71/233 (30%), Positives = 118/233 (50%), Gaps = 19/233 (8%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLK 63
GS + VLG GA V + N+ A+K N+ S D Q + E E+L+
Sbjct: 41 GSYTDDYKLGGVLGVGAFSQVRKVTNRKTKAVRAMKIINKRSLTNSEDQQKFINEVEILR 100
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
+ H +I+K+ E+ Q+ I++E+CTGG LF + + + E E ++ +
Sbjct: 101 LLDHPHILKIY--EQYQDNNNYYIILEMCTGGELFAKIIEKGS---FSEKEASYIMNQIV 155
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
+ + + ++ +VHRDLKP NI+ I DGT K+ D+G ++ +++E V +GT Y+
Sbjct: 156 SAVFYAHNHKIVHRDLKPENILLDITSDGTYNIKIVDWGTSKIFEQDEVMVEKFGTPYYI 215
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETM 236
P++ + KS+ D+WS GV LY + +G PF GG+ E M
Sbjct: 216 APEVLK---------KSYNEKCDVWSCGVILYILLSGTPPF---GGKNELEIM 256
>UniRef50_UPI0000F1ECF4 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 927
Score = 110 bits (264), Expect = 1e-22
Identities = 76/223 (34%), Positives = 113/223 (50%), Gaps = 21/223 (9%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGE-PVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
Y ++ ++G GA VF+G +K VAVK N+ + + + +E ++LK++KHE
Sbjct: 7 YEFNRKDLIGHGAFAVVFKGRHKQKHNFEVAVKCINRKNLAKSQSLLGKEIKILKELKHE 66
Query: 69 NIVKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
NIV LL + QE G V +VME C GG L L + L E ++L+ L M
Sbjct: 67 NIVSLL---DFQEISGCVYLVMEYCNGGDLAEYL---HSKGCLSEDTIRVLLQQLAGAMS 120
Query: 128 HLRDNNLVHRDLKPGNI-MKYI----NEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEY 182
LR ++HRDLKP NI + Y + KL DFG AR LQ +L G+ Y
Sbjct: 121 VLRSKGIIHRDLKPQNILLSYSTGRKSNPNNICIKLADFGFARYLQGNTMAATLCGSPMY 180
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+ P++ + ++ A DLWS+G +Y TG+ PF+
Sbjct: 181 MAPEVI--------MSHNYDAKADLWSVGTIIYQCLTGKAPFQ 215
>UniRef50_Q9VEZ5 Cluster: Inhibitor of nuclear factor kappa-B kinase
subunit beta; n=9; melanogaster subgroup|Rep: Inhibitor
of nuclear factor kappa-B kinase subunit beta -
Drosophila melanogaster (Fruit fly)
Length = 751
Score = 110 bits (264), Expect = 1e-22
Identities = 76/238 (31%), Positives = 110/238 (46%), Gaps = 25/238 (10%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRP-HDVQM-----REFEVLKKV 65
W LG+G G V N+ G +A K ++ + V++ +E ++
Sbjct: 41 WERCRNLGEGGFGLVIHWRNRTTGREIATKHIKEMGALSADQQVKLSERWNKELNWSRQF 100
Query: 66 KH-ENIVKLLAIEEEQ---------EGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEF 115
K+ +IV + IE+ + VIV+E C GG + L PEN GL E+E
Sbjct: 101 KNFPHIVAGVDIEDPDFLEYLNGMFSAKLPVIVLEYCNGGDVRKRLQSPENANGLTEFEV 160
Query: 116 LLVLEHLTAGMKHLRDN-NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV 174
+L L + L + HRDLKP NI+ DG YKLTDFG AR ++
Sbjct: 161 RQILGALRKALHFLHSQCGICHRDLKPDNIVIQRGVDGKKIYKLTDFGLARGTPDQTMVQ 220
Query: 175 SLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRN 232
S+ GT Y P++ E + +TVDLWS GV Y + TG+LPF P+ +N
Sbjct: 221 SVVGTRHYYAPEVVENGF--------YNSTVDLWSFGVIAYELVTGELPFIPHQTLKN 270
>UniRef50_Q24FQ7 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1158
Score = 109 bits (263), Expect = 1e-22
Identities = 68/226 (30%), Positives = 125/226 (55%), Gaps = 25/226 (11%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGE-PVAVKTFNQLSHMRPHDVQMR----EFEVL 62
+NY+ + +LG+G+ G+V+Q ++ NG+ VAVK +Q S + D M+ E + +
Sbjct: 14 DNYILNLDKILGQGSFGSVYQAIDMKNGDRQVAVKQISQTSMNKNADKLMQLLKNEIKTM 73
Query: 63 KKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHL 122
K +K +N+V+LL + + +++E C GGSL + L+ +N L E E L ++ +
Sbjct: 74 KMIKDKNVVQLLDVR--RSSNNIYLIVEYCNGGSLESYLN--KNGKRLSETETLRIIREI 129
Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ---EEEQFVSLYGT 179
+G K L + +VHRDLKP NI+ + DG K+ DFG ++ ++ E+ SL G+
Sbjct: 130 VSGFKCLYEQKIVHRDLKPANILLH---DGIP--KIADFGFSKVVEHSMEQADLASLVGS 184
Query: 180 EEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
Y+ P + +++ + +D+WS+G+ Y + G+ P++
Sbjct: 185 PIYMCPQILN--------CQTYSSKLDVWSLGIIFYEMLYGKTPWK 222
>UniRef50_A0BC68 Cluster: Chromosome undetermined scaffold_10, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_10,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1133
Score = 109 bits (261), Expect = 2e-22
Identities = 72/219 (32%), Positives = 116/219 (52%), Gaps = 22/219 (10%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVK 66
ENY ++G+G+ G V++G K + + A+K ++ +R E E+L+++K
Sbjct: 2 ENY--HVLHLIGEGSFGKVYKGRWKKSNQMAALKFISKRGKTEKDLANLRQEIEILRRLK 59
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
HENI+ LL E Q G+ ++ G L+ IL+D N L E E + + L +
Sbjct: 60 HENIILLLDAFETQ---GEFCLVTEFAQGELYEILEDDHN---LPESEVRKIAQQLVRAL 113
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHP 185
+L N ++HRD+KP NI+ ++ +G KL DFG AR + Q + S+ GT Y+ P
Sbjct: 114 HYLHSNRIIHRDMKPQNIL--LSANGVV--KLCDFGFARAMSTNTQVLHSIKGTPLYMAP 169
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ + + + TVDLWS+GV LY + GQ PF
Sbjct: 170 ELVQE--------QPYNHTVDLWSLGVILYELFVGQPPF 200
>UniRef50_Q8MQJ7 Cluster: LD18893p; n=4; Drosophila|Rep: LD18893p -
Drosophila melanogaster (Fruit fly)
Length = 855
Score = 108 bits (260), Expect = 3e-22
Identities = 76/238 (31%), Positives = 117/238 (49%), Gaps = 24/238 (10%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK---KVK 66
Y +S+ +LG GA V++G ++ PVA+K + ++ ++ +E ++LK ++
Sbjct: 7 YEYSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITKKGQLKTQNLLGKEIKILKELTELH 66
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
HEN+V LL +E Q+ +VME C GG L + L + T L E L L L M
Sbjct: 67 HENVVALLDCKESQDCVS--LVMEYCNGGDLADYL-SVKGT--LSEDTVRLFLVQLAGAM 121
Query: 127 KHLRDNNLVHRDLKPGNIM------KYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
K L +VHRDLKP NI+ K + T K+ DFG AR L E +L G+
Sbjct: 122 KALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKITLKIADFGFARFLNEGAMAATLCGSP 181
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFY 238
Y+ P++ + + + DLWS+G +Y TG+ PF Y N+ +Y
Sbjct: 182 MYMAPEVI--------MSLQYDSKADLWSLGTIVYQCLTGKAPF--YAQTPNELKSYY 229
>UniRef50_A5PLA2 Cluster: LOC558848 protein; n=2; Clupeocephala|Rep:
LOC558848 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 232
Score = 108 bits (259), Expect = 4e-22
Identities = 72/223 (32%), Positives = 115/223 (51%), Gaps = 21/223 (9%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGE-PVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
+ +S ++G GA VF+G ++ E VAVK N+ + + + +E ++LK++KHE
Sbjct: 7 FEFSRKDLIGHGAFAVVFKGRHREKHEWEVAVKCINKKNLAKSQTLLGKEIKILKELKHE 66
Query: 69 NIVKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
NIV A+ + QE V +VME C GG L + L L E + L+ +T M+
Sbjct: 67 NIV---ALHDFQETASSVYLVMEYCNGGDLADYLHSKGT---LSEDTIRVFLQQITGAMR 120
Query: 128 HLRDNNLVHRDLKPGNIM-----KYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEY 182
L+ ++HRDLKP NI+ + T K+ DFG AR LQ +L G+ Y
Sbjct: 121 VLQAKGIIHRDLKPQNILLSHPAGRKSHFNNTCIKIADFGFARYLQNNMMAATLCGSPMY 180
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+ P++ + +++ A DLWSIG ++ TG+ PF+
Sbjct: 181 MAPEVI--------MSQNYDAKADLWSIGTIVFQCLTGKAPFQ 215
>UniRef50_Q388H2 Cluster: Protein kinase, putative; n=1; Trypanosoma
brucei|Rep: Protein kinase, putative - Trypanosoma
brucei
Length = 1083
Score = 108 bits (259), Expect = 4e-22
Identities = 76/235 (32%), Positives = 115/235 (48%), Gaps = 19/235 (8%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFN--QLSHMRPHDVQMREFEVLKKVKHENIVKLL 74
++G G V+ GV+ G VA+K N +++ +EF VLK +KH NIV +
Sbjct: 306 LIGVGGFAKVYAGVDCVTGSLVAIKEINMAEVNDQEGFRAISKEFGVLKSLKHPNIVSYI 365
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
E + IVMEL TGGS ++L E LQE HL + +
Sbjct: 366 FFEHSVSQKVCRIVMELHTGGSTLSLL---ERFGPLQETILRRFSRHLLEAIAFIHQKGF 422
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVS-LYGTEEYLHPDMYERAVL 193
+HRD+KP NI+ ++ DG KL DFG + + E + + + GT Y+ P+ +
Sbjct: 423 LHRDIKPANIL--VSHDGVV--KLCDFGCCKRVNELNKSTNCVIGTPLYMAPEFIKGEGT 478
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGVI 248
K D+WS+G +L+ +ATG+LP+ G R + MFYITT S ++
Sbjct: 479 HKS---------DIWSMGCSLFELATGKLPWYHTGVRDHIPLMFYITTTSESPLV 524
>UniRef50_Q54MH0 Cluster: Putative uncharacterized protein fhkD;
n=1; Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein fhkD - Dictyostelium discoideum
AX4
Length = 749
Score = 107 bits (258), Expect = 6e-22
Identities = 70/223 (31%), Positives = 112/223 (50%), Gaps = 12/223 (5%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQL---SHMRPHDVQMREFEVLKKV 65
N +S +LG G V + + ++ GE AVK ++ S + E E+L+K+
Sbjct: 196 NKKYSIQGILGTGNFSVVKRCIRRDTGEVFAVKIIDKKKFWSQTKTRRQMESEVEILQKI 255
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
KH NI+ ++ I Q R IV+EL TGG LF + E E + +
Sbjct: 256 KHPNIISIIDIV--QSDRYFYIVLELATGGELFEKIKQKGR---FSEPEAKDTFKQILEA 310
Query: 126 MKHLRDNNLVHRDLKPGNIM-KYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
+ +L D N+ HRDLKP NI+ ++ ++ K+TDFG A+ + E+E +L GT Y+
Sbjct: 311 VSYLHDLNISHRDLKPENILISAVSHGKSSVIKVTDFGLAKIIGEKEMATTLCGTPLYVA 370
Query: 185 PDMYERAVL---RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ + V +G VD+WS+G LY + +G+ PF
Sbjct: 371 PEIIRNCLHGDGGAQVNTGYGKEVDVWSLGCILYILLSGRPPF 413
>UniRef50_A0DUI6 Cluster: Chromosome undetermined scaffold_64, whole
genome shotgun sequence; n=3; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_64, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 314
Score = 107 bits (258), Expect = 6e-22
Identities = 74/225 (32%), Positives = 115/225 (51%), Gaps = 19/225 (8%)
Query: 4 LRGSE--NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDV--QMREF 59
++G+E N V++ LG+GA G V + V K+ GE AVK N+ ++ D+ E
Sbjct: 1 MQGNEDINKVYTLEKTLGEGAFGVVKRAVKKSTGEHFAVKIINK-ENLSNEDLLALQTEV 59
Query: 60 EVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVL 119
E+L ++ H N+VKL I E+ +V+EL TGG LF + + ++ E E L
Sbjct: 60 EILTQIDHPNVVKLYEIYEDD--TYFYMVLELMTGGELFERIVEKDH---FSEKEAAATL 114
Query: 120 EHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGT 179
+ + + +VHRDLKP N++ E G K++DFG AR + EE ++ GT
Sbjct: 115 RPIIDALAYCHKMGIVHRDLKPENLLYSTMEPG-ALLKVSDFGLARFVGSEEVMMTQCGT 173
Query: 180 EEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
Y+ P++ GK + +D WS+GV LY + G PF
Sbjct: 174 PGYVAPEIIN--------GKGYTEAIDFWSVGVILYIMLCGFPPF 210
>UniRef50_A0DQ68 Cluster: Chromosome undetermined scaffold_6, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_6,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 503
Score = 107 bits (258), Expect = 6e-22
Identities = 68/234 (29%), Positives = 125/234 (53%), Gaps = 20/234 (8%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKH 67
E++ + +LG+GA V+ GV K+N + VAVK N+ ++ + L + +H
Sbjct: 12 EDFYETKNQLLGQGAFAQVYLGVKKSNKQKVAVKISNR--NLAISQQEKMVLISLSQYRH 69
Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
+N+V+LL I ++ E IV E C+GG+L+ ++ + T E + + + + G+
Sbjct: 70 QNVVQLLDIFDQPEAL--FIVQEYCSGGTLYEMMSNKTFT----EEQIVNIALQVAHGLA 123
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
L N+VHRD+KP NI++ I+E G YK+TDFG + ++ + + GT Y+ P++
Sbjct: 124 FLHSKNIVHRDIKPENILRQIDEQGMEIYKITDFGLS-SVKLDRMTTTKVGTAYYVAPEI 182
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
++ + + +VD+W++G+ + + + PF Y G +E F I T
Sbjct: 183 LDK--------QQYDKSVDVWALGLIIDEL-LHKTPF--YNGLSEEEVFFKIKT 225
>UniRef50_Q23R97 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1715
Score = 107 bits (257), Expect = 7e-22
Identities = 65/220 (29%), Positives = 121/220 (55%), Gaps = 19/220 (8%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN--QLSHMRPHDVQMREFEVLKKV 65
E+Y + + ++GKGA+G V+ G N + VA+K + Q+ + E +++KK+
Sbjct: 67 EDYTFCLSDLVGKGASGTVYLGENSVTKDLVAIKVIDLHQVKDEYTWGLICSEIDIMKKL 126
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
K EN+VKL+ + + Q I+ ELC G L + + N +++ + + ++ + G
Sbjct: 127 KCENVVKLIDVFQTQNNA--YIITELCEDGDLVDFMK--RNAGKIRQNQAVKIITDILRG 182
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLH 184
++ L + ++HRDLKP NI+ I++ +K+TDFG AR +++ + + SL GT Y+
Sbjct: 183 LQELAKHGIIHRDLKPANIL--ISK--KDVFKITDFGFARMVEKTDYLMTSLVGTPLYMS 238
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P + +R + + + D+WSIG+ Y + GQ P+
Sbjct: 239 PQILKR--------QMYTSKCDVWSIGLIFYELIYGQTPW 270
>UniRef50_Q4RYN4 Cluster: Chromosome 16 SCAF14974, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 16
SCAF14974, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1048
Score = 107 bits (256), Expect = 1e-21
Identities = 75/247 (30%), Positives = 125/247 (50%), Gaps = 23/247 (9%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGE-PVAVKTFNQLSHMRPHDVQMREFEVLKKVKH 67
++ +S ++G GA VF+G ++ + VA+K+ N+ + + + +E ++LK+++H
Sbjct: 6 DFEYSRKDLVGHGAFAVVFKGRHRKKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQH 65
Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
ENIV L ++E +VME C GG L + L + T L+E + L+ + A M+
Sbjct: 66 ENIVGLYDVQETPNS--VFLVMEYCNGGDLADYLQ-AKGT--LREDTLRVFLQQIAAAMR 120
Query: 128 HLRDNNLVHRDLKPGNIM------KYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEE 181
L ++HRDLKP NI+ K N G K+ DFG AR LQ +L G+
Sbjct: 121 ILNSKGIIHRDLKPQNILLSYAGRKKSNISG-IRIKIADFGFARYLQSNMMAATLCGSPM 179
Query: 182 YLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
Y+ P++ + +++ A DLWSIG +Y G+ PF+ + + MFY
Sbjct: 180 YMAPEVI--------MSQNYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLR--MFYEKN 229
Query: 242 KKASGVI 248
K +I
Sbjct: 230 KNLQPII 236
>UniRef50_A7PNU0 Cluster: Chromosome chr8 scaffold_23, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr8 scaffold_23, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 732
Score = 107 bits (256), Expect = 1e-21
Identities = 70/209 (33%), Positives = 112/209 (53%), Gaps = 17/209 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTF-NQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+G G+ V+ ++ +G VA+K + + + M E +LKK+ H NI++L I
Sbjct: 20 IGSGSFSVVWHARHRVHGTEVAIKEIVTGRLNKKLQESLMSEIFILKKINHPNIIRLHDI 79
Query: 77 EEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
E GK+ +V+E C GG L + ++ + E ++ L AG++ LRDNNL+
Sbjct: 80 IEVP---GKIHLVLEYCRGGDLSMYI---QSYVRVPEATAKHFMQQLAAGLQVLRDNNLI 133
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLKP N++ N D + K+ DFG AR LQ +L G+ Y+ P++ + L+K
Sbjct: 134 HRDLKPQNLLLSTN-DNNSVLKIADFGFARSLQPRGLAETLCGSPLYMAPEIMQ---LQK 189
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ A DLWS+G L+ + TG+ PF
Sbjct: 190 -----YDAKADLWSVGAILFQLVTGRTPF 213
>UniRef50_Q4N591 Cluster: Calcium-dependent protein kinase,
putative; n=2; Theileria|Rep: Calcium-dependent protein
kinase, putative - Theileria parva
Length = 844
Score = 106 bits (254), Expect = 2e-21
Identities = 68/219 (31%), Positives = 116/219 (52%), Gaps = 19/219 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG G+ G V +GV+K +G A+K + S + RE +++K + H NI+KL +
Sbjct: 406 LGNGSYGNVLKGVHKESGAVRAIKIILK-SKIENAMRMKREIQIMKTLDHPNIIKLFEVY 464
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E+ + +VME+C GG LF D +T G E ++ + + + + + N++HR
Sbjct: 465 EDADCL--YLVMEMCVGGELF---DRIVSTNGFSEAYAASIMRQVFSAIAYCHNRNVLHR 519
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NI+ Y+N+ ++T K+ D+G A + +F SL GT Y+ P++ +
Sbjct: 520 DLKPENIL-YMNDKPSSTIKIIDWGFATKCYRTHKFSSLVGTPYYVAPEVL--------L 570
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETM 236
G ++ D+WS GV L+ + G + P+ G N E +
Sbjct: 571 G-NYDKACDIWSAGVILFILLVG---YPPFHGSNNTEIL 605
>UniRef50_Q22C77 Cluster: Protein kinase domain containing protein;
n=11; Oligohymenophorea|Rep: Protein kinase domain
containing protein - Tetrahymena thermophila SB210
Length = 521
Score = 106 bits (254), Expect = 2e-21
Identities = 64/209 (30%), Positives = 111/209 (53%), Gaps = 18/209 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTF--NQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
LGKGA G V + ++K +G+ A+K N++S +++ E ++L+ + H NI+K+
Sbjct: 83 LGKGAYGEVRKAIHKASGQLRAIKIIKINEVSQEDKQNLE-NEIDILRNLDHPNIIKIF- 140
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
E ++ IV ELCTGG LF+ + + ++ E++ +++ + + + N +V
Sbjct: 141 -EFYKDSNYYYIVSELCTGGELFDKIIEEKS---FDEFKACNIIKQVLQAVNYCHSNKIV 196
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLKP N++ Y N+ + T K+ DFG +R E + GT Y+ P++ +
Sbjct: 197 HRDLKPENLL-YDNDTPSQTLKVIDFGTSRYYDPENKLTQRLGTPYYIAPEVLK------ 249
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + D+WS GV LY + G PF
Sbjct: 250 ---KEYNEKCDIWSCGVILYILLCGYPPF 275
>UniRef50_A0CNU2 Cluster: Chromosome undetermined scaffold_22, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_22,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 529
Score = 106 bits (254), Expect = 2e-21
Identities = 70/219 (31%), Positives = 114/219 (52%), Gaps = 21/219 (9%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQL---SHMRPHDVQMREFEVLKKV 65
NY +S ++LGKG+ G V+ G N PVA+K + ++ + + +E E++KK+
Sbjct: 17 NYGFSLKAILGKGSFGTVYFGREMNTQLPVALKVIDHSKSENYSQLYSSLHKEIEIMKKL 76
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
KH NIV+L E +V E C G L L + ++E + + +++ + G
Sbjct: 77 KHPNIVELY--EVYSTSNNTYLVEEYCNGPDLRQYLSEKRV---IEEDQAIKMIKQIANG 131
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
+K + +NN +HRDLKP NI+ + DG K+ DFG +R L E SL GT Y+ P
Sbjct: 132 LKEIVNNNFIHRDLKPANILIH---DGLC--KIADFGFSRPLPSECVMESLVGTPLYMAP 186
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+L K + + + D+WS+G+ Y + G LP+
Sbjct: 187 Q-----ILTK---QQYTSKCDVWSLGLIFYEMLFGTLPW 217
>UniRef50_Q6BFB4 Cluster: Protein kinase, putative; n=3; Paramecium
tetraurelia|Rep: Protein kinase, putative - Paramecium
tetraurelia
Length = 633
Score = 105 bits (253), Expect = 2e-21
Identities = 84/311 (27%), Positives = 150/311 (48%), Gaps = 49/311 (15%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKV 65
+NY +S + LGKGA G V+ G N + + VA+K ++ + + Q+ E E++KK+
Sbjct: 13 QNYQFSFRAKLGKGAYGTVYAGRNTFDNKIVALKVIDKKLLLTDYANQLIASEIEIMKKI 72
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPE---NTYG-LQEYEFLLVLEH 121
++VKLL + Q I+ E C GG L + + + +T+ + E E L ++
Sbjct: 73 NDSHVVKLLDVL--QSANNTYIITEYCNGGDLREFIKNRKYCIHTFRVIPEDEALKIMND 130
Query: 122 LTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV--SLYGT 179
L G+K L ++HRD+KP NI+ + N+ +K+TDFG A+++ + SL GT
Sbjct: 131 LLLGIKALLKIGIIHRDIKPANILIHDNQ-----FKITDFGFAKQIDANLDTIMNSLVGT 185
Query: 180 EEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
Y+ P + +R + + D+WS+G+ LY + G P+ + + + +
Sbjct: 186 PLYMSPQILKRT--------KYSSKCDVWSLGLILYEMLYGMTPW-------HSQNLVEL 230
Query: 240 TTKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFER 299
K S +S P H Q+S +KL+ G L+++ + W++E
Sbjct: 231 MNKLDSKPLS---------------FPVHPQVSENTKKLI----KGCLQINEEKRWSWED 271
Query: 300 FFSEVQVVTST 310
F+ V + T
Sbjct: 272 LFNSVNINLKT 282
>UniRef50_P11799 Cluster: Myosin light chain kinase, smooth muscle;
n=10; Euteleostomi|Rep: Myosin light chain kinase, smooth
muscle - Gallus gallus (Chicken)
Length = 1906
Score = 105 bits (253), Expect = 2e-21
Identities = 71/231 (30%), Positives = 121/231 (52%), Gaps = 18/231 (7%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENI 70
V++ LG G G VF+ V K G+ A K F S +++ E ++ + H +
Sbjct: 1452 VYNIEERLGSGKFGQVFRLVEKKTGKVWAGKFFKAYSAKEKENIR-DEISIMNCLHHPKL 1510
Query: 71 VKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLR 130
V+ ++ +E V+V+E+ +GG LF + D + + L E E + + ++ G++++
Sbjct: 1511 VQ--CVDAFEEKANIVMVLEMVSGGELFERIIDED--FELTERECIKYMRQISEGVEYIH 1566
Query: 131 DNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYER 190
+VH DLKP NIM +N+ G T+ KL DFG AR L+ L+GT E++ P++
Sbjct: 1567 KQGIVHLDLKPENIM-CVNKTG-TSIKLIDFGLARRLESAGSLKVLFGTPEFVAPEV--- 1621
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
+ +P+G D+WSIGV Y + +G PF G + ET+ +T+
Sbjct: 1622 -INYEPIGYE----TDMWSIGVICYILVSGLSPFM---GDNDNETLANVTS 1664
>UniRef50_UPI0000E48847 Cluster: PREDICTED: similar to titin isoform
N2-A; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to titin isoform N2-A - Strongylocentrotus
purpuratus
Length = 10984
Score = 105 bits (252), Expect = 3e-21
Identities = 69/224 (30%), Positives = 118/224 (52%), Gaps = 19/224 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG+G+ G V++ + K + A K R D+ RE EV+KK+ H ++ L +
Sbjct: 10325 LGRGSYGIVYRAIEKKTQKTWAAKFMRCFGKER--DLVRREIEVMKKLHHRRLLNLHEVF 10382
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E E ++++E +GG LF+ L D EN + L E E + ++ G+KH+ + +LVH
Sbjct: 10383 ETNEEI--IMILEFLSGGELFDRLVD-EN-HILTEPEVIFYMKQTCEGVKHMHERHLVHL 10438
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NIM + + K+ DFG EL ++ ++GT +++ P++ V +P+
Sbjct: 10439 DLKPENIM--LCARNSDDIKIIDFGLTMELDPDKPVKIMFGTPDFIAPEV----VNHEPI 10492
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
G D+W++GV Y + +G PF G ++ET+ + T
Sbjct: 10493 ----GLPTDMWALGVIAYLMLSGISPFE---GETDRETLKNVAT 10529
>UniRef50_Q6PDN3 Cluster: Myosin light chain kinase, smooth muscle;
n=34; Euteleostomi|Rep: Myosin light chain kinase, smooth
muscle - Mus musculus (Mouse)
Length = 1941
Score = 105 bits (252), Expect = 3e-21
Identities = 71/231 (30%), Positives = 121/231 (52%), Gaps = 18/231 (7%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENI 70
V+ LG G G VF+ V K G+ A K F S +++ +E ++ + H +
Sbjct: 1485 VYDIEERLGSGKFGQVFRLVEKKTGKIWAGKFFKAYSAKEKDNIR-QEISIMNCLHHPKL 1543
Query: 71 VKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLR 130
V+ ++ +E V+V+E+ +GG LF + D + + L E E + + ++ G++++
Sbjct: 1544 VQ--CVDAFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYIH 1599
Query: 131 DNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYER 190
+VH DLKP NIM +N+ G T KL DFG AR L+ L+GT E++ P++
Sbjct: 1600 KQGIVHLDLKPENIM-CVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEV--- 1654
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
+ +P+G + D+WSIGV Y + +G PF G + ET+ +T+
Sbjct: 1655 -INYEPIGYA----TDMWSIGVICYILVSGLSPFM---GDNDNETLANVTS 1697
>UniRef50_UPI00015B6173 Cluster: PREDICTED: similar to ikk-like
protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to ikk-like protein - Nasonia vitripennis
Length = 683
Score = 105 bits (251), Expect = 4e-21
Identities = 68/220 (30%), Positives = 108/220 (49%), Gaps = 18/220 (8%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM----REFEVLKKVKHENIVK 72
+LG G G V K + +A+K L D QM +E E +K H NIVK
Sbjct: 1 MLGAGGFGQVELWKEKYTNKRIAIKKC-MLPKGSITDRQMERWKQEIENMKHFNHPNIVK 59
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
+ E V+ ME C G L +L +PEN+ GL + + L V++ +++ + +L N
Sbjct: 60 SEQVPPEMVLNSPVLCMEFCNKGDLRKVLSNPENSCGLLQNDALTVMKDISSAVMYLHYN 119
Query: 133 NLVHRDLKPGNIMKY-----INEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
N+ HRDLKP NI+ + +N + G A+EL SL GT Y+ P++
Sbjct: 120 NITHRDLKPDNIVLHEKNGMVNNNVILKLDKLYLGYAKELGSTTMTASLVGTFNYVAPEL 179
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPY 227
+ + + + +VD WS+G+T + V +G PF+P+
Sbjct: 180 FWK--------QKYTCSVDYWSLGITFFEVISGHKPFQPH 211
>UniRef50_Q8IDV5 Cluster: Calcium-dependent protein kinase; n=7;
Plasmodium|Rep: Calcium-dependent protein kinase -
Plasmodium falciparum (isolate 3D7)
Length = 568
Score = 105 bits (251), Expect = 4e-21
Identities = 69/222 (31%), Positives = 117/222 (52%), Gaps = 25/222 (11%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKVKHENIVKLLA 75
LGKG+ G V + V+K G+ A+K + + H+++ RE ++K++ H NI+KL
Sbjct: 131 LGKGSYGNVVKAVSKRTGQQRAIKIIEK---KKIHNIERLKREILIMKQMDHPNIIKLYE 187
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E+ E +V+ELC GG LF D YG EYE +++ + + + + N+
Sbjct: 188 VYEDNEKL--YLVLELCDGGELF----DKIVKYGSFSEYEAYKIMKQIFSALYYCHSKNI 241
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
+HRDLKP NI+ Y++ + ++ D+G A + S+ GT Y+ P+ +LR
Sbjct: 242 MHRDLKPENIL-YVDNTEDSPIQIIDWGFASKCMNNHNLKSVVGTPYYIAPE-----ILR 295
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETM 236
GK + D+WS GV +Y + G + P+ G+ N E +
Sbjct: 296 ---GK-YDKRCDIWSSGVIMYILLCG---YPPFNGKNNDEIL 330
>UniRef50_Q23FR5 Cluster: Protein kinase domain containing protein;
n=2; Oligohymenophorea|Rep: Protein kinase domain
containing protein - Tetrahymena thermophila SB210
Length = 524
Score = 105 bits (251), Expect = 4e-21
Identities = 70/225 (31%), Positives = 111/225 (49%), Gaps = 20/225 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG GA G VF ++ G+ AVK + + E +LK++ H NI+KL +
Sbjct: 57 LGSGAFGVVFLATHRITGDERAVKAVAK-DRLSDKQQFQDEINILKELDHPNIIKLYEVY 115
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E + +V E C GG LF + + LQE + L++ L + + ++ DN ++HR
Sbjct: 116 ESESTI--YLVTEYCEGGELFQYVVQNKR---LQEKDAALIMRQLFSAVSYIHDNGVIHR 170
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP N + D TT K+ DFG +++ ++ E GT Y+ P++ E
Sbjct: 171 DLKPENFLLKKKSD-PTTIKMIDFGISKKFKKGEVLRQQSGTPYYIAPEVIE-------- 221
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTK 242
+ VD W++GV LY + +G PF YG +N + +FY K
Sbjct: 222 -GQYSEQVDNWALGVILYILLSGTPPF--YG--KNAQEIFYSIRK 261
>UniRef50_O45818 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 1101
Score = 105 bits (251), Expect = 4e-21
Identities = 73/219 (33%), Positives = 110/219 (50%), Gaps = 14/219 (6%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSH-MRPHDVQMREFEVLKKV 65
S+ Y VLG G G V+ G+++ NG+ VAVK ++L D+ E ++L+KV
Sbjct: 765 SQLYQIFAEEVLGSGQFGTVYGGIHRRNGQHVAVKLIDKLKFPPNKEDLLRAEVQILEKV 824
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
H +V + + E + +VME G L IL + + +FL+ +
Sbjct: 825 DHPGVVHFMQMLETTD--RIFVVMEKLKGDMLEMILSSEKGRLSERTTQFLVA--QILEA 880
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
+++L N+VH DLKP NI+ N D KL DFG AR + E+ S+ GT YL P
Sbjct: 881 LRYLHHLNIVHCDLKPENILLNSNSD-FPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAP 939
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ VLR K F ++D+WS+GV +Y +G PF
Sbjct: 940 E-----VLR---NKGFNRSLDMWSVGVIVYVSLSGTFPF 970
>UniRef50_A7RGL2 Cluster: Predicted protein; n=4; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 311
Score = 105 bits (251), Expect = 4e-21
Identities = 69/226 (30%), Positives = 115/226 (50%), Gaps = 21/226 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LGKG G V + VNK G+ A K F + S + + + E E++ ++H+ +++L
Sbjct: 27 LGKGRFGVVCKCVNKKTGKQFAAK-FIKCSKPQDREDVIHEMEIMNTIRHKRLLRLADAF 85
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E + ++VMEL TGG LF + + E + E + ++ + G++H+ ++H
Sbjct: 86 ETPSQQEMILVMELVTGGELFEKVVEEE---FISENDVTHYMKQILEGLEHMHKQEVLHL 142
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM--YERAVLRK 195
DLKP NIM I + + KL DFG AR+ +E ++GT E++ P++ Y+R
Sbjct: 143 DLKPENIM--IVKQDSRQIKLIDFGLARKYNPKENLKVMFGTPEFVAPEVLTYDRIT--- 197
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
D+WSIGV Y + +G PF G + ET+ + T
Sbjct: 198 -------PATDMWSIGVIAYVLLSGLSPFM---GDNDAETLANVQT 233
>UniRef50_A0BJ35 Cluster: Chromosome undetermined scaffold_11, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_11,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 464
Score = 105 bits (251), Expect = 4e-21
Identities = 69/210 (32%), Positives = 115/210 (54%), Gaps = 22/210 (10%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM-REFEVLKKVKHE 68
Y ++ ++GKGA G V++G++ N+G PVA+K ++ + + Q+ E +K++ H+
Sbjct: 8 YSFNMNHLIGKGAYGTVYKGIS-NDGLPVAIKVIDRRMINQTNTQQLLNEIRSMKQLNHK 66
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
NIVK L E Q I+ E C GG L +I+ + L + +L+ + G
Sbjct: 67 NIVKFLDFYETQNNF--YIISEFCNGGDLRDIIKRGK----LDSKSVVNILKQILNGYHQ 120
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ-EEEQFVSLYGTEEYLHPDM 187
L N+L+HRDLKP NI+ + G T KL DFG A+++ E + S+ GT Y+ P
Sbjct: 121 LYQNSLIHRDLKPANILLH---QGIT--KLADFGFAKKIDFENDLMTSIAGTPLYMAP-- 173
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHV 217
+ +LR+P + + D+WS+G+ LY +
Sbjct: 174 --QVILRQP----YTSKCDIWSLGMVLYEL 197
>UniRef50_Q761X0 Cluster: Putative uncharacterized protein; n=2;
Entamoeba histolytica|Rep: Putative uncharacterized
protein - Entamoeba histolytica
Length = 270
Score = 104 bits (250), Expect = 5e-21
Identities = 68/208 (32%), Positives = 112/208 (53%), Gaps = 16/208 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+GKGA V++ + K+ E VAVK + + P +Q E ++LK V H I+KL +
Sbjct: 14 IGKGAFSVVYEAIKKSTNEEVAVKVIDT-AKSDPQKLQ-GEIKILKMVDHPYIIKLYDVF 71
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+ +G+ I+ +L GG LF+ + D T+ E + +V++ L + + +L N+VHR
Sbjct: 72 DGNDGK-LYIITDLVKGGELFDRISD--KTF-YPEDKAKIVVKRLISAIGYLHSMNIVHR 127
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRKP 196
DLKP NI+ + D T ++ DFG ++ + E+ Q ++ GT Y+ P++
Sbjct: 128 DLKPENIL-LKSPDDDTDVRIADFGFSKMITEDAQILLTACGTPVYVAPEVLN------- 179
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
K +G VD+WSIGV Y + G PF
Sbjct: 180 -AKGYGMEVDMWSIGVITYVLLCGYPPF 206
>UniRef50_A7PBE5 Cluster: Chromosome chr16 scaffold_10, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr16 scaffold_10, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 1350
Score = 104 bits (249), Expect = 7e-21
Identities = 78/224 (34%), Positives = 119/224 (53%), Gaps = 28/224 (12%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPH-DVQ--MREFEVL 62
G ENY ++G+G+ G V++G K G+ VA+K L H + D+Q +E E+L
Sbjct: 2 GVENY--HVIELVGEGSFGKVYKGRRKFTGQTVAMKFI--LKHGKSEKDIQNLRQEIEIL 57
Query: 63 KKVKHENIVKLL-AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEH 121
+K+KHENI+++L + E QE +V E G LF IL+D + L E + + +
Sbjct: 58 RKLKHENIIEMLDSFETPQEF---CVVTEFAQG-ELFEILEDDKC---LPEEQVQAIAKQ 110
Query: 122 LTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTE 180
L + +L N ++HRD+KP NI+ + KL DFG AR + + S+ GT
Sbjct: 111 LVRALHYLHSNRIIHRDMKPQNILI----GAGSIVKLCDFGFARAMSTNTVVLRSIKGTP 166
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
Y+ P++ V +P + T DLWS+GV LY + GQ PF
Sbjct: 167 LYMAPEL----VREQP----YNHTADLWSLGVILYELFVGQPPF 202
>UniRef50_Q22S16 Cluster: Protein kinase domain containing protein;
n=5; Oligohymenophorea|Rep: Protein kinase domain
containing protein - Tetrahymena thermophila SB210
Length = 384
Score = 104 bits (249), Expect = 7e-21
Identities = 71/211 (33%), Positives = 109/211 (51%), Gaps = 20/211 (9%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR---EFEVLKKVKHENIVKL 73
VLG+G+ V + + K N E VAVK ++ + HD Q+ E E++ + H NIVK
Sbjct: 87 VLGEGSFAVVHKCIRKENNEEVAVKVIDKAN--LEHDDQLALETECEIMANIDHPNIVKC 144
Query: 74 LAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
+ +E+ +VMEL TGG LF+ + + E E E V++ + + +
Sbjct: 145 TCVYDEKSKF--YMVMELMTGGELFDRIVEKEF---YSEKEACDVIKPIVDAINYCHKMG 199
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVL 193
+ HRDLKP N++ Y + D T K++DFG A+ + +E + GT Y+ P++ E
Sbjct: 200 IAHRDLKPENLL-YTSPDPDATIKISDFGLAKVISDE-LMTTACGTPSYIAPEILE---- 253
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
GK + VD WSIGV LY + G PF
Sbjct: 254 ----GKGYTFAVDYWSIGVILYVLLCGFPPF 280
>UniRef50_A0DNC5 Cluster: Chromosome undetermined scaffold_58, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_58,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 495
Score = 104 bits (249), Expect = 7e-21
Identities = 67/220 (30%), Positives = 110/220 (50%), Gaps = 22/220 (10%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQL---SHMRPHDVQMREFEVLKK 64
E Y ++T V+GKG G V++GV++N VA+K + + E +LKK
Sbjct: 8 EKYFYNTGHVIGKGNYGCVYKGVDQNTQTDVAIKIVKKTKLEGESYSQKAFINEMMILKK 67
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
+ +NIVKL + E Q ++ ELC G L IL + + L E E + +L + +
Sbjct: 68 LSSKNIVKLFDVCESQS--NYYLIQELCQQGDLKKILKEQQ----LNEKEAIKILRDILS 121
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
G + L +VHRD+KP NI +N +G +KL DFG A ++ +++ GT Y+
Sbjct: 122 GYQILLKYGIVHRDIKPANI---LNSNG--VFKLGDFGLATQISKQKMLNQCVGTPLYMS 176
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P + + + ++ + D+WSIG+ Y G P+
Sbjct: 177 PQVQQHS--------NYTSKCDIWSIGILFYESLYGATPW 208
>UniRef50_A4RK67 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 677
Score = 104 bits (249), Expect = 7e-21
Identities = 78/230 (33%), Positives = 114/230 (49%), Gaps = 21/230 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHM----RPHDVQMREFEVLKKVKHENIVKL 73
LGKG VF V K+ G+ AVK F+ + + R +Q+ E VL V H N++ L
Sbjct: 266 LGKGHFAEVFACVEKSTGQRYAVKIFSMVPGLEERSRTEGLQL-EIAVLMGVSHPNVLCL 324
Query: 74 LAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
+ EG +V+EL G LFN + + L E E + L G+K+L D N
Sbjct: 325 K--DTFHEGNAVYLVLELAPEGELFNFIVMKQK---LSEAESRKLFTQLFHGVKYLHDRN 379
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVL 193
+VHRD+KP NI+ +++D K+ DFG A+ + EE SL GT Y+ P++
Sbjct: 380 IVHRDIKPENIL-LVDKD--LHVKIADFGLAKIIGEESFTTSLCGTPSYVAPEILVDGRH 436
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
RK + VD+WS+GV LY G F P+ E+ Y T++
Sbjct: 437 RK-----YTKAVDVWSLGVVLYICLCG---FPPFSDELTSESFPYTLTQQ 478
>UniRef50_Q9SX42 Cluster: F14I3.15 protein; n=2; Arabidopsis
thaliana|Rep: F14I3.15 protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 1097
Score = 103 bits (248), Expect = 9e-21
Identities = 74/222 (33%), Positives = 116/222 (52%), Gaps = 24/222 (10%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLK 63
G E+Y ++G+G+ G V++G K G+ VA+K F D+ +E E+L+
Sbjct: 2 GVEDY--HVIELVGEGSFGRVYKGRRKYTGQTVAMK-FIMKQGKTDKDIHSLRQEIEILR 58
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+KHENI+++L + + R +V E G LF IL+D + L E + + + L
Sbjct: 59 KLKHENIIEML--DSFENAREFCVVTEFAQG-ELFEILEDDKC---LPEEQVQAIAKQLV 112
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEY 182
+ +L N ++HRD+KP NI+ + KL DFG AR + + S+ GT Y
Sbjct: 113 KALDYLHSNRIIHRDMKPQNILI----GAGSVVKLCDFGFARAMSTNTVVLRSIKGTPLY 168
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P++ V +P + TVDLWS+GV LY + GQ PF
Sbjct: 169 MAPEL----VKEQP----YDRTVDLWSLGVILYELYVGQPPF 202
>UniRef50_Q2QAV0 Cluster: Fused; n=3; core eudicotyledons|Rep: Fused
- Arabidopsis thaliana (Mouse-ear cress)
Length = 1322
Score = 103 bits (248), Expect = 9e-21
Identities = 74/222 (33%), Positives = 116/222 (52%), Gaps = 24/222 (10%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLK 63
G E+Y ++G+G+ G V++G K G+ VA+K F D+ +E E+L+
Sbjct: 2 GVEDY--HVIELVGEGSFGRVYKGRRKYTGQTVAMK-FIMKQGKTDKDIHSLRQEIEILR 58
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+KHENI+++L + + R +V E G LF IL+D + L E + + + L
Sbjct: 59 KLKHENIIEML--DSFENAREFCVVTEFAQG-ELFEILEDDKC---LPEEQVQAIAKQLV 112
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEY 182
+ +L N ++HRD+KP NI+ + KL DFG AR + + S+ GT Y
Sbjct: 113 KALDYLHSNRIIHRDMKPQNILI----GAGSVVKLCDFGFARAMSTNTVVLRSIKGTPLY 168
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P++ V +P + TVDLWS+GV LY + GQ PF
Sbjct: 169 MAPEL----VKEQP----YDRTVDLWSLGVILYELYVGQPPF 202
>UniRef50_A0E776 Cluster: Chromosome undetermined scaffold_80, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_80,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 445
Score = 103 bits (248), Expect = 9e-21
Identities = 66/236 (27%), Positives = 121/236 (51%), Gaps = 24/236 (10%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
+Y + + LG+GA G V++G+N N E VA+K + + + +Q++E E++ K+ H+
Sbjct: 6 HYTYDEINCLGQGAYGKVYEGLNTLNNETVAIKKLDLILFEKDKIIQVQEIEIMSKLNHK 65
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
NIVK +E + IV E+C G L +++ + + E + + ++ + G K
Sbjct: 66 NIVKF--VELLATKKSLFIVTEMCRSGDLKSLI----ASKNISEQQAIDIMLQILEGFKE 119
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAR--ELQEEEQFVSLYGTEEYLHPD 186
L + ++HRD+KP N+ +N+ GT K+ DFG A+ E + S G+ Y+ P
Sbjct: 120 LIKSGVIHRDMKPANV---LNDMGTV--KIADFGFAKYVENYSSQLLKSCVGSPLYMAPQ 174
Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTK 242
+ ER + D+WS+GV Y + +P++ GR ++ + I T+
Sbjct: 175 VLER--------HHYSTKCDIWSLGVIFYEMLHFDVPWK---GRDEEDLLHNIKTQ 219
>UniRef50_A0C9W0 Cluster: Chromosome undetermined scaffold_16, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_16,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 464
Score = 103 bits (248), Expect = 9e-21
Identities = 71/227 (31%), Positives = 124/227 (54%), Gaps = 27/227 (11%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTF---NQLSHMRPHDVQMREFEVLK 63
S+ + W VLG+GA G V G+ KN G+ +AVK NQ+ + +Q +E E+L
Sbjct: 62 SDIHNWEQGEVLGQGAFGKVVMGLQKN-GQIMAVKQVFIQNQIDD-KVRQLQ-KEIEMLS 118
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHL 122
K++H NIV+ + E++ + I +E +GGS+ +L+ +G +E L+ +
Sbjct: 119 KLQHPNIVRYMGCEQKNQFIN--IFLEYVSGGSVSTLLE----RFGCFRERLIKTYLKQI 172
Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQE--EEQFVSLYGTE 180
G+ +L N++HRD+K GNI+ I+ G KL DFG++++L + + S+ GT
Sbjct: 173 LLGLSYLHAKNVIHRDIKGGNIL--IDNSGRC--KLADFGSSKQLNDITHDSIGSICGTP 228
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPY 227
++ P++ + + +G D+WS+G T+ +ATGQ P+ Y
Sbjct: 229 NFMAPEVINQ--------EQYGKKADIWSLGCTVIEMATGQPPYSEY 267
>UniRef50_Q75CE9 Cluster: ACR142Wp; n=1; Eremothecium gossypii|Rep:
ACR142Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 837
Score = 103 bits (248), Expect = 9e-21
Identities = 67/211 (31%), Positives = 108/211 (51%), Gaps = 11/211 (5%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
V+G+GA V + V +N G+ AVK N+ M D RE EVL+++ H IV L
Sbjct: 222 VVGQGAFATVKKAVERNTGKTFAVKIINKRKVMGNVDGVTRELEVLRRLNHPRIVSLKGF 281
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E+ E ++ME +GG L + + + G E + + ++++ + + H
Sbjct: 282 YEDDE--SYYLLMEFVSGGDLMDFV-AAHGSVG--EDAGREITRQILEAVRYIHEQGISH 336
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMY--ERAVL 193
RDLKP NI+ I +D K+TDFG A+ +Q+ F+ + GT Y+ P++ +
Sbjct: 337 RDLKPDNIL--IEQDDPVLVKITDFGLAK-IQDNTTFMKTFCGTLAYVAPEVIGGKNPEG 393
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
G + + VD+WSIG +Y + TG LPF
Sbjct: 394 NGANGNLYSSLVDMWSIGCLVYVILTGHLPF 424
>UniRef50_Q8IYT8 Cluster: Serine/threonine-protein kinase ULK2;
n=17; Euteleostomi|Rep: Serine/threonine-protein kinase
ULK2 - Homo sapiens (Human)
Length = 1036
Score = 103 bits (248), Expect = 9e-21
Identities = 68/223 (30%), Positives = 114/223 (51%), Gaps = 19/223 (8%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGE-PVAVKTFNQLSHMRPHDVQMREFEVLKKVKH 67
++ +S ++G GA VF+G ++ + VA+K+ N+ + + + +E ++LK+++H
Sbjct: 6 DFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQH 65
Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
ENIV L ++E +VME C GG L + L + T L E + L + A M+
Sbjct: 66 ENIVALYDVQELP--NSVFLVMEYCNGGDLADYL-QAKGT--LSEDTIRVFLHQIAAAMR 120
Query: 128 HLRDNNLVHRDLKPGNI-MKYINEDGTTT----YKLTDFGAARELQEEEQFVSLYGTEEY 182
L ++HRDLKP NI + Y N ++ K+ DFG AR L +L G+ Y
Sbjct: 121 ILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMY 180
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+ P++ + + + A DLWSIG +Y G+ PF+
Sbjct: 181 MAPEVI--------MSQHYDAKADLWSIGTVIYQCLVGKPPFQ 215
>UniRef50_O75385 Cluster: Serine/threonine-protein kinase ULK1;
n=32; Eumetazoa|Rep: Serine/threonine-protein kinase
ULK1 - Homo sapiens (Human)
Length = 1050
Score = 103 bits (248), Expect = 9e-21
Identities = 70/223 (31%), Positives = 109/223 (48%), Gaps = 21/223 (9%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGE-PVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
+ +S ++G GA VF+G ++ + VAVK N+ + + + +E ++LK++KHE
Sbjct: 14 FEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHE 73
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
NIV L +E +VME C GG L + L L E L L+ + M+
Sbjct: 74 NIVALYDFQE--MANSVYLVMEYCNGGDLADYLHAMRT---LSEDTIRLFLQQIAGAMRL 128
Query: 129 LRDNNLVHRDLKPGNIMKYINEDG------TTTYKLTDFGAARELQEEEQFVSLYGTEEY 182
L ++HRDLKP NI+ N G + K+ DFG AR LQ +L G+ Y
Sbjct: 129 LHSKGIIHRDLKPQNIL-LSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMY 187
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+ P++ + + + DLWSIG +Y TG+ PF+
Sbjct: 188 MAPEVI--------MSQHYDGKADLWSIGTIVYQCLTGKAPFQ 222
>UniRef50_Q10292 Cluster: Meiosis-specific serine/threonine-protein
kinase mek1; n=1; Schizosaccharomyces pombe|Rep:
Meiosis-specific serine/threonine-protein kinase mek1 -
Schizosaccharomyces pombe (Fission yeast)
Length = 445
Score = 103 bits (248), Expect = 9e-21
Identities = 64/213 (30%), Positives = 107/213 (50%), Gaps = 8/213 (3%)
Query: 14 TTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKL 73
T +LG G ++ ++ N G A K ++ + E +L+K+ H NI+K+
Sbjct: 162 TQRLLGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKRFFEDHEMTILRKLDHPNIIKV 221
Query: 74 LAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
+E E + I E+ TGG LF+ L + E L ++ + G+K+L + N
Sbjct: 222 -NMEYNSETQF-FIFEEMVTGGDLFSYLTKLGT---VPEVTTLFIMFQILQGLKYLHEQN 276
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE---R 190
++HRDLK NI+ + D LTDFG AR +Q+ ++ + GT EY P++ R
Sbjct: 277 IIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKGKRLSTFVGTPEYTAPEIQRLKGR 336
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + K +G VDLWS+GV ++ + +G P
Sbjct: 337 SQVEKENSSGYGKEVDLWSLGVIMFLLLSGNSP 369
>UniRef50_A7ANH6 Cluster: Protein kinase domain containing protein;
n=1; Babesia bovis|Rep: Protein kinase domain containing
protein - Babesia bovis
Length = 755
Score = 103 bits (247), Expect = 1e-20
Identities = 67/210 (31%), Positives = 109/210 (51%), Gaps = 16/210 (7%)
Query: 15 TSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLL 74
T+ LGKG+ G V + +K GE AVK + + ++ RE ++K + H NIVKLL
Sbjct: 303 TNRLGKGSYGQVLKACHKETGEVKAVKVIRKAAIENAMRMK-REITIMKNLDHPNIVKLL 361
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
I E++E +VME+C+GG LF ++ E ++ L + + + +
Sbjct: 362 EIYEDEE--CLYLVMEMCSGGELF---EEIVRRGCFSEQYAATMMRQLFSAIAYCHGKGI 416
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
+HRDLKP NI+ Y N + K+ D+G A + + +F SL GT Y+ P++
Sbjct: 417 LHRDLKPENIL-YANTSDNSPIKVIDWGFATKCYKTHKFTSLVGTPYYVAPEVL------ 469
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G S+ + D+WS GV ++ + G PF
Sbjct: 470 --IG-SYDKSCDMWSAGVIMFIMLVGYPPF 496
>UniRef50_A2DLZ6 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 972
Score = 103 bits (247), Expect = 1e-20
Identities = 70/209 (33%), Positives = 107/209 (51%), Gaps = 20/209 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM-REFEVLKKVKHENIVKLLAI 76
+G+G+ G V++ K G VA+K N+L + RE +LKKV H +I+++L +
Sbjct: 10 IGEGSFGRVYKARRKFTGRLVAIKMINKLGQSKDDLTSFKREINILKKVNHPHIMRMLDM 69
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E +V EL G LF I+DD + L E V LT+ + +L N ++H
Sbjct: 70 FESDTDFN--VVSELARG-DLFQIIDDNQT---LPEDVLKTVAAQLTSALAYLHKNKIIH 123
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAVLRK 195
RD+KP NI+ I G KL DFG AR L F+ S+ GT Y+ P++ +
Sbjct: 124 RDMKPQNIL--ITNKG--ALKLCDFGFARALSSTTLFLNSIKGTPLYMAPELVQE----- 174
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + +D+WS+G+ LY + GQ PF
Sbjct: 175 ---QRYDEKIDVWSLGIILYELFYGQPPF 200
>UniRef50_A0C9C9 Cluster: Chromosome undetermined scaffold_16, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_16,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 505
Score = 103 bits (247), Expect = 1e-20
Identities = 72/223 (32%), Positives = 119/223 (53%), Gaps = 22/223 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLL-AI 76
+G G G V + K N E A+K +++ + + + +EF+ LK + H NI+KL +
Sbjct: 52 IGAGGQGCVIKVRCKLNNEVRAMKVIKKINEDKNENFR-KEFQNLKLLDHPNILKLYHSF 110
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E++Q+ I+ ELC GG+L +DD Y L+E E L +++ L + NLVH
Sbjct: 111 EDDQKF---YIISELCEGGTLSQYIDDH---YPLKEAEVLKIMKQLIGSINFAHAKNLVH 164
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RD+KP NI+ I+++ T+ KL D+G + +Q+ E+ GT ++ P++ E
Sbjct: 165 RDIKPENIL--IDDEVATSIKLIDWGFSGMIQKYEKLSLKCGTIHFVAPEVME------- 215
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
+S+ D+WS GV LY + PF+ G +KE +F I
Sbjct: 216 --ESYDQKCDIWSCGVVLYILLCNDPPFQ---GTDSKEILFNI 253
>UniRef50_Q869W6 Cluster: Similar to Xenopus laevis (African clawed
frog). Calcium/calmodulin- dependent protein kinase I
alpha; n=2; Dictyostelium discoideum|Rep: Similar to
Xenopus laevis (African clawed frog).
Calcium/calmodulin- dependent protein kinase I alpha -
Dictyostelium discoideum (Slime mold)
Length = 349
Score = 103 bits (246), Expect = 2e-20
Identities = 70/209 (33%), Positives = 106/209 (50%), Gaps = 17/209 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLAI 76
LG+GA V +G K + VA+K + + H Q+R E +++KKVKHEN++ L I
Sbjct: 62 LGRGAFSVVREGTRKTTSDKVALKYIEKKFVKKKHIEQLRREIDIMKKVKHENVLSLKEI 121
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E +VMEL TGG LF + + + E V+ + AG+++L + H
Sbjct: 122 FESDSHL--TLVMELVTGGELFYKIVERGS---FTEKGARNVVRQVCAGVEYLHSQGIAH 176
Query: 137 RDLKPGNIMKYINEDG-TTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ N +G T K+ DFG ++ E + GT +Y+ P++
Sbjct: 177 RDLKPENLL--CNGEGEDMTIKIADFGLSKIFGTGEALETSCGTPDYVAPEVL------- 227
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
G S+ VD+WSIGV Y + G PF
Sbjct: 228 -TGGSYDNAVDMWSIGVITYILLCGFPPF 255
>UniRef50_A7RI47 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 251
Score = 103 bits (246), Expect = 2e-20
Identities = 71/220 (32%), Positives = 113/220 (51%), Gaps = 17/220 (7%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKV 65
GS + + +GKGA G V + V+K G+ A K S+ MRE EV++K+
Sbjct: 6 GSADEFYDMNEEIGKGAYGIVKKCVDKATGQTYAAKVVTT-SNSNLRKETMREIEVMRKL 64
Query: 66 -KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
H+ +V L I+ V+++E GG LF + E Y L E + + + +
Sbjct: 65 GSHKKLVGL--IDAYHTPFEIVMILEFIPGGELFERII--EEDY-LMEEDAIYYVHQVLL 119
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
+ ++ NN+VH DLKP NIM + KL DFG AREL+++E+ S +GT +++
Sbjct: 120 ALDYMHGNNIVHLDLKPENIM--CESINSNQIKLVDFGLARELKKDEEVKSSFGTPDFVA 177
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ + KPV D+WS+GV Y + +G +PF
Sbjct: 178 PEV----IRMKPV----STASDMWSLGVVTYVLLSGLMPF 209
>UniRef50_A0C1C8 Cluster: Chromosome undetermined scaffold_141,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_141,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 457
Score = 102 bits (245), Expect = 2e-20
Identities = 70/221 (31%), Positives = 118/221 (53%), Gaps = 26/221 (11%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFE--VLKKV 65
E Y ++T+++LG G+ G V++G+N +P+A+K + + +D + FE +L K+
Sbjct: 12 EKYQYNTSNILGDGSYGTVYKGINTLTQQPIAIKV---IPRQKVYDAEALSFELRILAKL 68
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
K +NIV+L Q ++I +LC G L +LD + T+ L E E + ++ L G
Sbjct: 69 KGDNIVRLHETLMTQNNYYQII--DLC-DGDLKQLLD--KQTF-LTEQEAINMMIDLLRG 122
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQE--EEQFVSLYGTEEYL 183
L N ++HRD+KP NI+ I++ TYKL DFG AR + ++ FV++ GT Y+
Sbjct: 123 FLELIQNGIIHRDVKPANIL--ISKG---TYKLADFGFARLVDNYAQQLFVTVLGTPLYM 177
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P + + + D+WS+G Y V G+ P+
Sbjct: 178 SPQLLQNL--------QYSTKCDIWSLGFIFYEVLFGRTPW 210
>UniRef50_Q15746 Cluster: Myosin light chain kinase, smooth muscle;
n=40; Theria|Rep: Myosin light chain kinase, smooth
muscle - Homo sapiens (Human)
Length = 1914
Score = 102 bits (245), Expect = 2e-20
Identities = 69/224 (30%), Positives = 118/224 (52%), Gaps = 18/224 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG G G VF+ V K + A K F S +++ +E ++ + H +V+ ++
Sbjct: 1470 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIR-QEISIMNCLHHPKLVQ--CVD 1526
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+E V+V+E+ +GG LF + D + + L E E + + ++ G++++ +VH
Sbjct: 1527 AFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYIHKQGIVHL 1584
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NIM +N+ G T KL DFG AR L+ L+GT E++ P++ + +P+
Sbjct: 1585 DLKPENIM-CVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEV----INYEPI 1638
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
G + D+WSIGV Y + +G PF G + ET+ +T+
Sbjct: 1639 GYA----TDMWSIGVICYILVSGLSPFM---GDNDNETLANVTS 1675
>UniRef50_UPI00005A4286 Cluster: PREDICTED: similar to doublecortin
and CaM kinase-like 3; n=2; Canis lupus familiaris|Rep:
PREDICTED: similar to doublecortin and CaM kinase-like 3
- Canis familiaris
Length = 755
Score = 102 bits (244), Expect = 3e-20
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 19/224 (8%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLG G V + ++ + A+K ++ D+ E +++ + H NIV+L
Sbjct: 468 VLGDGNFAVVKECRHRQTRQAYAMKIIDKARLRGKEDMVHSEILIIQSLSHPNIVQL--- 524
Query: 77 EEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
E E G+V ++ME GG LF+ + + + E + L+L L + HL D ++V
Sbjct: 525 HEVYETEGEVYLIMEYVQGGDLFDAITE---SVRFAERDAALLLLDLCRALVHLHDKSIV 581
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLKP N++ NED +TT KL DFG A+ + ++ GT Y+ P++
Sbjct: 582 HRDLKPENLLVQRNEDKSTTLKLADFGLAKHV--VRPIFTVCGTPTYVAPEILSE----- 634
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
K +G VD+W+ GV LY + G PFR R+++ +F I
Sbjct: 635 ---KGYGLEVDMWAAGVILYILLCGFPPFR--SPERDQDELFNI 673
>UniRef50_Q24DL4 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 861
Score = 102 bits (244), Expect = 3e-20
Identities = 70/222 (31%), Positives = 109/222 (49%), Gaps = 23/222 (10%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ---MREFEVLKK 64
+ Y + +SVLG+G+ G VF+G N NG+ VA+K + + E +++KK
Sbjct: 175 DKYHFQLSSVLGQGSFGKVFKGKNTENGQLVAIKMIEKKQIQNDEYLMNGLFSEIQIMKK 234
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
+K E +V L+ + E I+ E C GG + L +N L E E L V++ L
Sbjct: 235 LKSEYVVDLIDVLE--TSNNYYIIQEYCDGGDFRSELKKRKN---LSEQESLNVMKDLLN 289
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ--EEEQFVSLYGTEEY 182
G L N ++HRDLKP NI+ N+ +KL DFG AR + + + SL GT Y
Sbjct: 290 GFMDLLKNGIIHRDLKPENILIKGNQ-----HKLADFGFARTVDNFQRQMLTSLVGTPLY 344
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P + + + + A DLWS+ Y + G+ P+
Sbjct: 345 MSPQIL--------MHEKYTAKSDLWSLAFIFYEMLYGKTPY 378
>UniRef50_UPI0000D8B5E1 Cluster: Unc-51 like kinase 2 (C. elegans);
n=4; Eutheria|Rep: Unc-51 like kinase 2 (C. elegans) -
Mus musculus
Length = 1062
Score = 101 bits (243), Expect = 4e-20
Identities = 67/223 (30%), Positives = 112/223 (50%), Gaps = 19/223 (8%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGE-PVAVKTFNQLSHMRPHDVQMREFEVLKKVKH 67
++ + ++G GA VF+G ++ + VA+K+ N+ + + + +E ++LK+++H
Sbjct: 6 DFEYCKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQH 65
Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
ENIV L ++E +VME C GG L + L + T L E + L + A M+
Sbjct: 66 ENIVALYDVQELP--NSVFLVMEYCNGGDLADYL-QAKGT--LSEDTIRVFLHQIAAAMR 120
Query: 128 HLRDNNLVHRDLKPGNI-MKYINEDGTTT----YKLTDFGAARELQEEEQFVSLYGTEEY 182
L ++HRDLKP NI + Y N + K+ DFG AR L +L G+ Y
Sbjct: 121 ILHSKGIIHRDLKPQNILLSYANRRKSNVSGIRIKIADFGFARYLHSNTMAATLCGSPMY 180
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+ P++ + + + A DLWSIG +Y G+ PF+
Sbjct: 181 MAPEVI--------MSQHYDAKADLWSIGTVIYQCLVGKPPFQ 215
>UniRef50_Q6BFK9 Cluster: SNF1-related protein kinase, putative;
n=4; Paramecium tetraurelia|Rep: SNF1-related protein
kinase, putative - Paramecium tetraurelia
Length = 562
Score = 101 bits (243), Expect = 4e-20
Identities = 75/219 (34%), Positives = 111/219 (50%), Gaps = 22/219 (10%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVK 66
NY T LG G G V +++ +GE VA+K + + DV+ RE +LK V+
Sbjct: 20 NYAIGKT--LGFGTFGKVKMAIHEQSGEKVAIKILEKDRIVETADVERVQREIHILKLVR 77
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
H +I++L I E + +VME+ GG LF+ + +NT L+E E + + L AG+
Sbjct: 78 HPHIIQLYEIIETP--KHIFLVMEMVNGGELFDYI--VKNTK-LEEVEACKLFQELIAGI 132
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPD 186
++L +VHRDLKP N++ D K+ DFG + + EE + G+ Y P+
Sbjct: 133 EYLHKIRVVHRDLKPENLLL----DKGKNLKIVDFGLSNTYKNEELLKTACGSPCYAAPE 188
Query: 187 MYERAVLRKPVGKSF-GATVDLWSIGVTLYHVATGQLPF 224
M GK + G VDLWS GV L+ G LPF
Sbjct: 189 MI--------AGKKYQGLRVDLWSSGVILFACLCGYLPF 219
>UniRef50_A0CDT9 Cluster: Chromosome undetermined scaffold_17, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_17,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 489
Score = 101 bits (243), Expect = 4e-20
Identities = 71/233 (30%), Positives = 114/233 (48%), Gaps = 19/233 (8%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPH-DVQMREFEVLKKVK 66
+NY + VLG GA G V + +K +G+ A+KT + + D E +L+K+
Sbjct: 49 DNY-YILGDVLGVGAFGQVIKATHKQSGQIRALKTLAKKKIINEEKDKMFAEVNILRKLD 107
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
H NIVKL + E+ G+ ++ EL GG L + +NT+ E E + L + +
Sbjct: 108 HPNIVKLFELFED--GQNYYLITELIQGGELIKKIQ-AQNTFS--EAEAAFYMRQLLSAL 162
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTT-TYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
++ +VHRDLK N+M +N D K+ DFG +R++ +E+ S GT Y P
Sbjct: 163 QYCHKAKIVHRDLKLENLM--LNADSEKPVLKVIDFGTSRKIIQEKYLTSKLGTPHYTAP 220
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFY 238
+++++ K D+WS GV LY + G LPF R + + Y
Sbjct: 221 EVFKQQYTEK---------CDIWSCGVILYTLLCGYLPFNGSDARATQILIEY 264
>UniRef50_UPI0000E809AA Cluster: PREDICTED: similar to regulated in
COPD kinase transcript; n=2; Gallus gallus|Rep:
PREDICTED: similar to regulated in COPD kinase transcript
- Gallus gallus
Length = 1281
Score = 101 bits (242), Expect = 5e-20
Identities = 80/231 (34%), Positives = 116/231 (50%), Gaps = 24/231 (10%)
Query: 2 SFLRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVK-----TFNQLSHMRPHDVQM 56
S L + +W+ VLGKGA G V+ G+ N G+ +AVK T +QL+ + +
Sbjct: 1004 SNLNNKDTIMWTRGEVLGKGAYGTVYCGLT-NQGQLIAVKQVVLDTSDQLTTEKEYQKLH 1062
Query: 57 REFEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEF 115
E ++LK +KH NIV L E I ME GGS+ +IL N +G L E
Sbjct: 1063 EEVDLLKTLKHVNIVTYLGTCLEDNILS--IFMEFVPGGSISSIL----NRFGPLPEIVL 1116
Query: 116 LLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVS 175
+ + G+ +L DN +VHRD+K N+M N KL DFG AR L +VS
Sbjct: 1117 CKYTKQILEGVAYLHDNCVVHRDIKGNNVMLMPNG----IVKLIDFGCARRLA----WVS 1168
Query: 176 LYGTEEYLHPDMYERAVLRKP--VGKS-FGATVDLWSIGVTLYHVATGQLP 223
L GT + ++ P + +S +G D+WSIG T++ +ATG+ P
Sbjct: 1169 LSGTHSEMLKSVHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPP 1219
>UniRef50_UPI0000D555E5 Cluster: PREDICTED: similar to CG7717-PB,
isoform B; n=2; Endopterygota|Rep: PREDICTED: similar to
CG7717-PB, isoform B - Tribolium castaneum
Length = 1250
Score = 101 bits (242), Expect = 5e-20
Identities = 66/236 (27%), Positives = 116/236 (49%), Gaps = 21/236 (8%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKVKH 67
+ W +G+G G V+ VN GE +AVK L H H ++ E ++L+ + H
Sbjct: 980 FTWQRGIKIGQGRFGKVYTAVNNKTGEMMAVKEL-PLQHNDTHTIKRVGEEMKILEGIVH 1038
Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
N+V+ +E ++ +I ME C G+L ++ EN GL E L +G+
Sbjct: 1039 RNLVRYYGVEIHKD--EMLIFMEFCAEGTLETLVAASEN--GLPELLVRRYTFQLVSGVA 1094
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEE----QFVSLYGTEEYL 183
L D+ +VHRD+K NI ++ E+G K+ DFG A +++ + GT+ Y+
Sbjct: 1095 VLHDHGIVHRDIKTANI--FLTENG-NCLKIGDFGCAAKIKSHSTMPGELQGFVGTQAYM 1151
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
P+++ R + + G D+WS+G + +A+G+ P+ + N + MF +
Sbjct: 1152 APEVFTR-----NMSEGHGRAADIWSVGCVVVEMASGKRPWAQFDS--NYQIMFKV 1200
>UniRef50_Q235N6 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 541
Score = 101 bits (241), Expect = 6e-20
Identities = 60/225 (26%), Positives = 114/225 (50%), Gaps = 18/225 (8%)
Query: 3 FLRGSENYVWSTTSV---LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREF 59
F++ + +W + +G+G G V + V+K E AVK Q S + + E
Sbjct: 43 FVQKNNGKIWEDYIIHNQIGQGHFGVVKKVVHKITNEERAVKII-QKSQEKAQKYSLNEI 101
Query: 60 EVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVL 119
E+L+ + H +I+K+ E++ +V+EL GG LF+ + + L+E + ++
Sbjct: 102 ELLRSLDHPHILKIYEFYEDKNNF--YVVLELLKGGELFDKISEGNM---LKEKQAQEIM 156
Query: 120 EHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGT 179
+ + + + N++HRDLKP NI+ ++ K+ D+G A +++E + +GT
Sbjct: 157 RQILSAIIYAHSQNVMHRDLKPENILLEVDSSDNFNIKVIDWGGAMRFEQDELYYDFFGT 216
Query: 180 EEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ Y+ P+ Y+ + + DLWSIGV L+ + +G+ PF
Sbjct: 217 KLYMSPEQYQ---------QKYNYKCDLWSIGVILFILISGESPF 252
>UniRef50_Q54BF0 Cluster: Putative uncharacterized protein fhkA;
n=1; Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein fhkA - Dictyostelium discoideum
AX4
Length = 593
Score = 100 bits (240), Expect = 9e-20
Identities = 71/228 (31%), Positives = 109/228 (47%), Gaps = 25/228 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM-----REFEVLKKVKHENIVK 72
LG G V++GVNKN G+ VA+K N LS + H + RE E+LK + HEN+V+
Sbjct: 186 LGSGNFSVVYEGVNKNTGKRVAIKHLN-LSKINTHTPKFKSQLNREIEILKFINHENVVE 244
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
+ I ++ + ++EL GG L+N + E L E + + + + + +L
Sbjct: 245 IYDIFYTKDQQ-LFFILELANGGELYNKIGFNEPL--LNENQSKFIFKQILNAVSYLHSK 301
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAV 192
+ HRDLKP NI+ D K+TDFG AR + E E +L G+ Y+ P++
Sbjct: 302 GIAHRDLKPENILFDSYGDDYLKIKITDFGLARFIHEGELAKTLCGSPLYVAPEVILSLH 361
Query: 193 LRKPVGKS----------------FGATVDLWSIGVTLYHVATGQLPF 224
+ G + +G + D WS+G LY V G PF
Sbjct: 362 HKNKYGTNSSSSSQSPTKDINSVGYGKSCDAWSLGAILYIVLCGTPPF 409
>UniRef50_A0DN99 Cluster: Chromosome undetermined scaffold_57, whole
genome shotgun sequence; n=5; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_57, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 506
Score = 100 bits (240), Expect = 9e-20
Identities = 65/208 (31%), Positives = 106/208 (50%), Gaps = 16/208 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLAI 76
+GKGA G V + ++K + AVK ++ + ++R E E+LK++ H NI+K+
Sbjct: 49 IGKGAFGEVRKAIHKVTNQIRAVKVISKEKASKVEVERLRIEIEILKRLDHPNIIKIY-- 106
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E Q+ + IV ELCTGG LF+ + D + E + ++ + + + +L + +VH
Sbjct: 107 EFYQDHKNIYIVTELCTGGELFDKIQDQQ---AFSERKAAETMKQVLSAVNYLHKSKIVH 163
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP NI+ N+ K+ DFG +R + + GT Y+ P++ ER
Sbjct: 164 RDLKPENILYEANKP-QALLKIVDFGTSRVFETGYKMNQKLGTPYYIAPEVLER------ 216
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ D+WS GV LY + G PF
Sbjct: 217 ---KYDEKCDVWSCGVILYILLCGLPPF 241
>UniRef50_A0C1X6 Cluster: Chromosome undetermined scaffold_143,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_143,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 489
Score = 100 bits (240), Expect = 9e-20
Identities = 66/219 (30%), Positives = 109/219 (49%), Gaps = 19/219 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G G VF+ K+ G A+K + + + E +L+K+ H NI+K+ +
Sbjct: 44 IGAGGFGVVFETEQKSTGIKRAIKAIAK-DRVVDKESFKNELSILRKIDHPNILKMYEVY 102
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E + + +V E+C GG LF + T L E + ++ + + +L ++ +VHR
Sbjct: 103 ETE--KTVYLVTEMCEGGELFYYIT---KTQHLTEMQAAKIMRQIFTAVAYLHEHKIVHR 157
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP N + N+D ++ KL DFG AR +E+E G+ Y+ P++ +
Sbjct: 158 DLKPENFL-LKNKDDESSIKLIDFGLARFFREDEVMTQPNGSLFYIAPEI---------I 207
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETM 236
+ VD WS+GV LY + GQ PF GR +ET+
Sbjct: 208 KGQYSYEVDYWSLGVILYVMMCGQPPF---PGRNPQETI 243
>UniRef50_Q96NX5 Cluster: Calcium/calmodulin-dependent protein
kinase type 1G; n=19; Euteleostomi|Rep:
Calcium/calmodulin-dependent protein kinase type 1G -
Homo sapiens (Human)
Length = 476
Score = 100 bits (240), Expect = 9e-20
Identities = 70/208 (33%), Positives = 111/208 (53%), Gaps = 16/208 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLG GA VF + G+ A+K + R ++ E VLKK+KHENIV L I
Sbjct: 28 VLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLE-NEIAVLKKIKHENIVTLEDI 86
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E +VM+L +GG LF+ + + Y E + LV++ + + +K+L +N +VH
Sbjct: 87 YESTTHY--YLVMQLVSGGELFDRILE-RGVY--TEKDASLVIQQVLSAVKYLHENGIVH 141
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP N++ Y+ + + +TDFG ++ +++ + GT Y+ P++ + +KP
Sbjct: 142 RDLKPENLL-YLTPEENSKIMITDFGLSK-MEQNGIMSTACGTPGYVAPEV----LAQKP 195
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
K+ VD WSIGV Y + G PF
Sbjct: 196 YSKA----VDCWSIGVITYILLCGYPPF 219
>UniRef50_UPI0001554A4C Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 521
Score = 100 bits (239), Expect = 1e-19
Identities = 70/215 (32%), Positives = 107/215 (49%), Gaps = 15/215 (6%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHEN 69
Y S T +LG G G V + K +G +A K DV+ E V+ ++ H N
Sbjct: 224 YSVSRTEILGGGRFGQVHKCEEKASGLKLAAKIIKTRGVKEKDDVK-NEISVMNQLNHVN 282
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
I++L E + V+VME GG LF+ + D EN Y L E + +L ++ + G+K++
Sbjct: 283 IIQLYDAFESKNDI--VLVMEYVDGGELFDRIID-EN-YNLTELDTILFIKQICEGVKYM 338
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189
++H DLKP NI+ +N D K+ DFG AR + E+ +GT E+L P++
Sbjct: 339 HQMYILHLDLKPENIL-CVNRD-AKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVN 396
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P D+WSIGV Y + +G PF
Sbjct: 397 YDFVSFP--------TDMWSIGVMAYMLLSGLSPF 423
>UniRef50_UPI00006CBD17 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 640
Score = 100 bits (239), Expect = 1e-19
Identities = 68/222 (30%), Positives = 112/222 (50%), Gaps = 24/222 (10%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ---MREFEVLKKV 65
NY ++ LG+GA G V++GV KN + VA+K + + ++ + E E+LK+
Sbjct: 40 NYSYNLRHCLGEGAYGKVYEGVEKNTQQTVAIKKLDIRQFQNDNYLRNSIISEIEILKRF 99
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
H+NIVK + + Q R I+ E C L ++ + L E + L VL + G
Sbjct: 100 NHKNIVKFIDLITTQ--RSLYIITEFCKDKDLRFLIQNKR----LTENQALHVLRDIVEG 153
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAR--ELQEEEQFVSLYGTEEYL 183
K L +N++HRDLKP NI+ IN+ +K+ DFG A+ + + S G+ Y+
Sbjct: 154 FKELVKHNVIHRDLKPANIL--INDQ---VFKIADFGFAKYVDYSSAQLLRSCVGSPLYM 208
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
P + R K++G D+WSIGV + + +P++
Sbjct: 209 APQILAR--------KAYGLKSDIWSIGVIFHEMVYQDVPWK 242
>UniRef50_Q6BFF5 Cluster: Protein kinase, putative; n=2; Paramecium
tetraurelia|Rep: Protein kinase, putative - Paramecium
tetraurelia
Length = 489
Score = 100 bits (239), Expect = 1e-19
Identities = 71/222 (31%), Positives = 110/222 (49%), Gaps = 23/222 (10%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTF---NQLSHMRPHDVQMREFEVLKK 64
+NY + T+ VLG G+ G VFQG + N+ VA+K N L+ + E ++KK
Sbjct: 7 DNYTFLTSDVLGVGSFGTVFQGFDLNSNRYVAMKMIAKDNLLNDPKGQSGLKTEINIMKK 66
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
+ H+NIV+L+ + E Q I+ ELC G L L +N ++ ++L+ L
Sbjct: 67 LNHKNIVQLIDVLETQ--NNIYIIQELCENGDLSKFL--KKNKLVDEKMALNIILDVL-Q 121
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ--EEEQFVSLYGTEEY 182
G L ++HRDLKP NI+ + N TYKL DFG ++ ++ S GT Y
Sbjct: 122 GFYELLKYRIIHRDLKPANILIHNN-----TYKLADFGFSKFVENFNPNTLQSQVGTPLY 176
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P +LR + + D+WS+G Y + GQ P+
Sbjct: 177 MSPQ-----ILR---NEKYSMKCDIWSLGFLFYEILYGQTPW 210
>UniRef50_Q5CTY5 Cluster: Calcium/calmodulin dependent protein
kinase with a kinas domain and 4 calmodulin-like EF
hands; n=3; Cryptosporidium|Rep: Calcium/calmodulin
dependent protein kinase with a kinas domain and 4
calmodulin-like EF hands - Cryptosporidium parvum Iowa
II
Length = 718
Score = 100 bits (239), Expect = 1e-19
Identities = 70/208 (33%), Positives = 108/208 (51%), Gaps = 17/208 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+GKG G+V G N+ G A+KT L+ + D M+E +LK + H NIVKL E
Sbjct: 207 IGKGTYGSVKSGTNRLTGCIRAIKTI-PLTRVEALDNFMKEINILKNLDHPNIVKL--YE 263
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
Q+ +VMELC+GG LF D + E +++ + + + + D+ +VHR
Sbjct: 264 TYQDKENIYLVMELCSGGELF---DRIISQGSFDEIYAANLMKQVLSTICYCHDHGIVHR 320
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
DLKP N + ++N++ K+ DFG AAR E+ + GT Y+ P++ +
Sbjct: 321 DLKPENFL-FLNKNYNAPLKIIDFGLAARVNNEDTSLNTRAGTPYYVAPEVLQ------- 372
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
GK + D+WS+GV LY + G PF
Sbjct: 373 -GK-YDKQCDMWSLGVILYILLCGYPPF 398
>UniRef50_A0D911 Cluster: Chromosome undetermined scaffold_41, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_41,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 651
Score = 100 bits (239), Expect = 1e-19
Identities = 70/221 (31%), Positives = 118/221 (53%), Gaps = 22/221 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKV 65
+NY +S + LGKGA G V+ G N + + VA+K ++ + + Q+ E E++K +
Sbjct: 13 QNYQFSFKAKLGKGAYGTVYGGRNIVDNKIVALKIVDKKILLTDYASQLIASEIEIMKLI 72
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
+ +NIV+L I+ Q I+ E C GG L L ++ + E + + VL+ L G
Sbjct: 73 EDKNIVRL--IDVLQSVNNTYIITEFCNGGDLREYLKKRKS---IPENDAINVLKDLLHG 127
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV--SLYGTEEYL 183
+K L ++HRD+KP NIM + DG +K+TDFG A+++ + SL GT Y+
Sbjct: 128 IKALLKIGIIHRDIKPANIMIH---DG--VFKITDFGFAKQVDSHIDTIMNSLVGTPLYM 182
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P + +R +S+ + D+WS+G+ Y + G P+
Sbjct: 183 SPQILKR--------QSYTSKCDIWSLGLIFYELIYGITPW 215
>UniRef50_A0C9K2 Cluster: Chromosome undetermined scaffold_16, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_16,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 759
Score = 100 bits (239), Expect = 1e-19
Identities = 71/252 (28%), Positives = 118/252 (46%), Gaps = 25/252 (9%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN--QLSHMRPHDVQMREFEVLKKVK 66
NY + ++G G + V++GVN + VA+K + QL+ + E +VL +
Sbjct: 14 NYTYENNDLIGSGYSSKVYKGVNTKTNQVVAIKVISIQQLTTQISKSLLKNEIQVLSLID 73
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
H N++K+ E + R ++ E C L ILD + T E + L V + + G+
Sbjct: 74 HPNLMKIYDTFETKNNR--YLICEYCNERDLAEILDSTQFT----ETQTLEVFQQIAQGI 127
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY--GTEEYLH 184
K L D ++HRD+KP NI+K +YKL DFG A + E + + GT Y+
Sbjct: 128 KALHDKKIIHRDIKPANILK-----SNGSYKLADFGFAVIENQYESIIKKFNVGTPMYMA 182
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP-FRPYGGRRNKETMFYITTKK 243
P+ + V + D+WS+G+ L+ + +LP F +K+ F I K
Sbjct: 183 PETAQNNV--------YSEKSDIWSLGIVLFQMIYRELPLFSKQENELSKKHSFLI-NKI 233
Query: 244 ASGVISGTQTTE 255
+ I+ +T E
Sbjct: 234 KNDTITTPKTKE 245
>UniRef50_A0C5A6 Cluster: Chromosome undetermined scaffold_15, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_15,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 687
Score = 100 bits (239), Expect = 1e-19
Identities = 62/221 (28%), Positives = 109/221 (49%), Gaps = 23/221 (10%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRP--HDVQMREFEVLKKV 65
+ Y + +LG+G + +V++G+N + VA+K N + P + E +LK++
Sbjct: 13 QKYSYFLNDILGEGYSSSVYKGINYITNQVVAIKVINFSTLTTPISQTLLKNEIAILKQL 72
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
HEN++K+ I E + I+ E C G L NIL+ T + + + + + G
Sbjct: 73 DHENLMKVYEIFETKNNT--YIICEYCNDGDLANILEKSNFT----QADIMNIFLQIAKG 126
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY--GTEEYL 183
+K L D ++HRD+KP NI++ YKL+DFG A + E + + GT Y+
Sbjct: 127 VKALHDQKIIHRDIKPANILR-----SNGIYKLSDFGFAIVENDFESIIKRFSVGTPVYM 181
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P+ + S+ D+WS+GV LY + ++P+
Sbjct: 182 APETVQ--------SNSYSEKSDIWSLGVVLYLMVYKEIPY 214
>UniRef50_UPI00006CC451 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 762
Score = 99 bits (238), Expect = 1e-19
Identities = 65/222 (29%), Positives = 119/222 (53%), Gaps = 24/222 (10%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN----QLSHMR-PHDVQMREFEVLKK 64
Y ++ + LGKG+ G V++G E VA+K N Q+ + + D +E ++++
Sbjct: 13 YEFNCSDTLGKGSFGTVYKGRVIATNEVVAIKALNRSLLQIQNQKFMIDQLKKEINLMQE 72
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
+K E+IV++ + + I++E C G L +L+ +N Y + E + + +L+ +
Sbjct: 73 IKSEHIVRIYDLVGTETHI--YIIIEYCGDGDLRGLLE--KNNYNISESQAISILQQILQ 128
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV--SLYGTEEY 182
G K L D VHRD+KP NI+ IN++ T+K+ DFG A ++Q++ V G+ Y
Sbjct: 129 GFKSLIDQGYVHRDIKPENIL--INKN---TFKIADFGFATKIQDQNAQVLKECVGSPLY 183
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P + ++ K + + D+WSIG+ Y + G+LP+
Sbjct: 184 MSPQLLQQ--------KPYSSKSDIWSIGLLYYEILFGKLPW 217
>UniRef50_Q240Z1 Cluster: Protein kinase domain containing protein;
n=3; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 515
Score = 99 bits (238), Expect = 1e-19
Identities = 65/225 (28%), Positives = 113/225 (50%), Gaps = 19/225 (8%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKN--NGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
V+ SV+GKGA G V KN N + +A+K ++ + + +RE +++K + H
Sbjct: 36 VYEFQSVIGKGAFGTVKLACLKNSINDKNIAIKIIDKSMLKQKQYLLLRELDMMKNLDHP 95
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
NI+K + +++ I ME C GG L + + E E +++E + + + H
Sbjct: 96 NIIKFYEVYQDE--MFFYICMEYCAGGELLERITKKKV---FSEKEASIIMEKIFSAINH 150
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMY 188
+ +VHRD+KP NI+ + N+ + KL DFG + + + ++ GT Y+ P++
Sbjct: 151 MHSRGVVHRDIKPENIL-FSNKYPDSEIKLIDFGLSTKFDDNSNLSTMVGTPIYVSPNVL 209
Query: 189 ERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNK 233
+ GK + T D WS GV LY + G PF +G +N+
Sbjct: 210 D--------GK-YDKTCDNWSAGVILYILLVGYPPF--FGNNKNE 243
>UniRef50_Q19A76 Cluster: Checkpoint kinase 2-like; n=12;
Pezizomycotina|Rep: Checkpoint kinase 2-like -
Neurospora crassa
Length = 702
Score = 99 bits (238), Expect = 1e-19
Identities = 73/210 (34%), Positives = 105/210 (50%), Gaps = 16/210 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHM--RPHDVQMR-EFEVLKKVKHENIVKLL 74
LGKG V+ V K+ G AVK F++ + R D ++ E VL V H N++ L
Sbjct: 296 LGKGHFAEVYLCVEKSTGTQYAVKVFSKTPGVEERSKDEGLQQEIAVLMGVSHPNVLCLK 355
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E +V+EL GG LFN + L E E + L G+K+L D N+
Sbjct: 356 --DTFNEPNAVHLVLELAPGGELFNYIVKKTK---LSENECRKLFTQLFQGVKYLHDRNI 410
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
VHRD+KP NI+ +++D KL DFG A+ + EE +L GT Y+ P+ +L
Sbjct: 411 VHRDIKPENIL-LVDDD--LHVKLADFGLAKIIGEESFTTTLCGTPSYVAPE-----ILT 462
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + VD+WS+GV LY G PF
Sbjct: 463 DTRHRKYTKAVDVWSLGVVLYICLCGFPPF 492
>UniRef50_UPI00006CB13C Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 529
Score = 99.5 bits (237), Expect = 2e-19
Identities = 72/224 (32%), Positives = 116/224 (51%), Gaps = 22/224 (9%)
Query: 9 NYVWSTTSVLGKGATGAVF-----QGVNKNNGEPV-AVKTFNQLSHMRPHDVQMREFEVL 62
NY + S LGKG+ G+V QG N + + A+KT + + RE EVL
Sbjct: 33 NYFYKIISQLGKGSFGSVKLATYRQGQNDRREKKLFAIKTILKDRVKDKIYMLQRELEVL 92
Query: 63 KKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHL 122
K + H NI+K E + VME C GG LF + N L+E+E +++ L
Sbjct: 93 KTLDHPNIIKFY--ETYHDKMYIHFVMEYCPGGDLFEYV---ANKGPLEEFEAAQIMKKL 147
Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTT-TYKLTDFGAAREL-QEEEQFVSLYGTE 180
+ + H+ N+VHRDLKP NI+ + ++D T+ K+ DFG +R+ +++ +S+ GT
Sbjct: 148 FSAVAHIHSKNIVHRDLKPENIL-FTSKDKTSWDIKIIDFGLSRQFNSNDKKHMSVVGTP 206
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
Y+ P++ K++ D WS+GV +Y + +G+ PF
Sbjct: 207 LYVAPEIIGE--------KNYEKECDNWSLGVIMYILLSGREPF 242
>UniRef50_Q9VE37 Cluster: CG7717-PA, isoform A; n=6; Eumetazoa|Rep:
CG7717-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 1612
Score = 99.5 bits (237), Expect = 2e-19
Identities = 71/238 (29%), Positives = 116/238 (48%), Gaps = 20/238 (8%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKV 65
S ++ W +G+G G V+ VN N GE +A+K Q R E ++L+ +
Sbjct: 1318 SVHFRWHRGIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGI 1377
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
KH+N+V+ IE +E +I MELC+ G+L +++ E T L E L +G
Sbjct: 1378 KHKNLVRYYGIEVHRE--ELLIFMELCSEGTLESLV---ELTGNLPEALTRRFTAQLLSG 1432
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEE----QFVSLYGTEE 181
+ L + +VHRD+K NI DG+ + KL DFG+A ++Q + GT+
Sbjct: 1433 VSELHKHGIVHRDIKTANIFLV---DGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQA 1489
Query: 182 YLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
Y+ P+ V K G D+WS+G + +A+G+ P+ + N + MF +
Sbjct: 1490 YMAPE-----VFTKTNSDGHGRAADIWSVGCVVVEMASGKRPWAQFDS--NFQIMFKV 1540
>UniRef50_Q54PX0 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 496
Score = 99.5 bits (237), Expect = 2e-19
Identities = 67/210 (31%), Positives = 109/210 (51%), Gaps = 21/210 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTF--NQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
+G+GA G VF+G+N GE VA+K N++ V+ E E+L K++H NIVK+L
Sbjct: 42 IGRGAFGQVFKGLNGKTGEFVAIKQIDSNKIDESSLQSVK-GEVEILHKLRHNNIVKVLG 100
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E Q ++E GSL +++ E L E ++ L + G+ +L N ++
Sbjct: 101 VVEVQAQLN--FILEYVENGSLRDVI---EKFGPLSEELCIIYLYQMLQGLAYLHSNKVI 155
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQF-VSLYGTEEYLHPDMYERAVLR 194
HRD+K NI+ I ++G KL DFG A ++ E Q S+ GT ++ P+ E +
Sbjct: 156 HRDIKASNIL--ITKEG--VIKLADFGVASQIDSESQLRFSVVGTPYWMAPESIEIS--- 208
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ D+WS+G T+ + TG P+
Sbjct: 209 -----GCSSASDIWSLGSTMIELLTGNPPY 233
>UniRef50_A2E7E2 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 311
Score = 99.5 bits (237), Expect = 2e-19
Identities = 61/208 (29%), Positives = 107/208 (51%), Gaps = 15/208 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHM-RPHDVQMREFEVLKKVKHENIVKLLAI 76
+G+G V+ G + + + VA+K ++ + + D+Q +E ++ K+ + IV +
Sbjct: 15 IGQGGFSRVYLGESLKDQKKVAIKVISKTNDLCEMKDIQ-KEIKIQKQFESPYIVTFYDM 73
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E + + VIVME GG LF D E E +++ + G+K L + ++H
Sbjct: 74 YETK--KEIVIVMEYVNGGELF---DHIVQKGSFTEQEAANIIQQVLIGLKVLHEKKVIH 128
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP N++ +I+E G TT K+ DFG + + E GTE Y P++ +
Sbjct: 129 RDLKPENLLLFIDEKGNTTVKIADFGLSGLIDNSEDMKRFCGTEGYAAPEIMKNV----- 183
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ +VD+WS+GV +Y++ +G PF
Sbjct: 184 ---PYDWSVDVWSLGVIVYNLVSGYKPF 208
>UniRef50_Q5K8X6 Cluster: Protein threonine/tyrosine kinase,
putative; n=1; Filobasidiella neoformans|Rep: Protein
threonine/tyrosine kinase, putative - Cryptococcus
neoformans (Filobasidiella neoformans)
Length = 674
Score = 99.5 bits (237), Expect = 2e-19
Identities = 62/211 (29%), Positives = 102/211 (48%), Gaps = 10/211 (4%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQ---LSHMRPHDVQMREFEVLKKVKHENIVKLL 74
LGKG V + V+ G A+K + + + + RE + + ++HENI +L
Sbjct: 208 LGKGTFAEVHKAVDVETGNMRAIKQIVKHRFAGNDKTLQLFHREINITRSLEHENICRL- 266
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFN-ILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
I+ ++ + +V+E GG L + I+D PE GL E + + M +
Sbjct: 267 -IDWYEDPQHICLVLEYVDGGDLLDYIMDWPEEQGGLPEQHAAELTVQICRAMAYTHSKG 325
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVL 193
+ HRDLKP NI+ +G K+ DFG A+ + VS+ GT +YL P++ V+
Sbjct: 326 ITHRDLKPENILLTKEHEGARIVKIADFGLAKMIHTNTMLVSMVGTPQYLAPEI----VM 381
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + VD WS+G+ +Y + T LPF
Sbjct: 382 QTEQQPGYENVVDSWSVGIIVYSMMTKALPF 412
>UniRef50_Q9P7I2 Cluster: Calcium/calmodulin-dependent protein
kinase type I; n=10; Ascomycota|Rep:
Calcium/calmodulin-dependent protein kinase type I -
Schizosaccharomyces pombe (Fission yeast)
Length = 335
Score = 99.5 bits (237), Expect = 2e-19
Identities = 62/213 (29%), Positives = 108/213 (50%), Gaps = 15/213 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLG G V + V+ + A K N+ + D E +LK+V +E+ L +
Sbjct: 36 VLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIAILKRVSYEHPNILHLV 95
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+ + ++ EL TGG LF+ + + Y E + ++ T+ +K+L DN +VH
Sbjct: 96 DFFETVNNLYLITELATGGELFDRICAKGSFY---EADAAALMRTTTSAVKYLHDNGIVH 152
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQF--VSLYGTEEYLHPDMYERAVLR 194
RDLKP N++ Y ++D + + DFG + ++ + + ++ GT EY+ P+++ R
Sbjct: 153 RDLKPENLL-YRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGTPEYMAPEVFRRT--- 208
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF-RP 226
+G VD+W+IGV Y + +G PF RP
Sbjct: 209 -----GYGKPVDMWAIGVITYFLLSGYTPFARP 236
>UniRef50_UPI00015B5E56 Cluster: PREDICTED: similar to myosin light
chain kinase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to myosin light chain kinase - Nasonia
vitripennis
Length = 764
Score = 99.1 bits (236), Expect = 3e-19
Identities = 69/229 (30%), Positives = 120/229 (52%), Gaps = 20/229 (8%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
S +G+G G V++ K G +A K N V+ RE E++++++H +++L
Sbjct: 38 SEIGRGKFGTVYRCKEKKTGLTLAAKVVNTTRKEDRRAVE-REVEIMRRLQHPRLIQLY- 95
Query: 76 IEEEQEGRGKVIVMELCTGGSLFN-ILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
+ + G+ +V+EL GG LF ++DD + L E + + + G++ + N+
Sbjct: 96 -DAIENGKQIYVVLELIEGGELFERVIDDD---FVLTERSCAVFMRQICEGIEFVHSQNI 151
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
+H D+KP NI+ + ++G K+ DFG ARE +++ L+GT E++ P++ V
Sbjct: 152 IHLDMKPENIL-CLTKEGNRI-KIIDFGLAREWDPKKKLQVLFGTPEFVAPEV----VNF 205
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+G FG D+WSIGV Y + +G PF G + ETM +T K
Sbjct: 206 DQIG--FG--TDMWSIGVICYVLLSGLSPFM---GDTDVETMANVTIAK 247
>UniRef50_Q8MYF1 Cluster: Similar to Dictyostelium discoideum (Slime
mold). Protein kinase 2; n=2; Dictyostelium
discoideum|Rep: Similar to Dictyostelium discoideum
(Slime mold). Protein kinase 2 - Dictyostelium
discoideum (Slime mold)
Length = 456
Score = 99.1 bits (236), Expect = 3e-19
Identities = 77/245 (31%), Positives = 120/245 (48%), Gaps = 22/245 (8%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDV--QMREFEVLKKVKHENIVKL- 73
++GKG G VFQ V+ + + A+K + + V + E ++LKK+ H IV L
Sbjct: 133 LVGKGGFGKVFQVVHVDTQKVYALKVIKKNHIIAKKSVVNTLAEKDILKKISHPFIVNLH 192
Query: 74 LAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
A + E++ +VM+ GG LF L E + + F + L ++HL D+N
Sbjct: 193 YAFQNEKK---LYLVMDFVNGGQLFYHLQK-EAIFSEDQVRFYMA--ELILALEHLHDSN 246
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAAR-ELQEEEQFVSLYGTEEYLHPDMYERAV 192
+VHRDLKP NI+ ++ G LTDFG A+ E++ + S GT EY+ P+M + A
Sbjct: 247 IVHRDLKPENIL--LDSQGHCI--LTDFGLAKLEVKTNNETFSFAGTLEYMAPEMIQHA- 301
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGVISGTQ 252
+ G VD WSIG+ +Y + G+ PF +E + K V S +
Sbjct: 302 -------TCGKAVDWWSIGILMYDMMIGKPPFEHKNRALMQEKIISEKAKFPKFVSSSAR 354
Query: 253 TTENG 257
+ NG
Sbjct: 355 SLING 359
>UniRef50_Q24HR9 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 593
Score = 99.1 bits (236), Expect = 3e-19
Identities = 65/222 (29%), Positives = 110/222 (49%), Gaps = 23/222 (10%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDV---QMREFEVLKKVK 66
YV+S +LG+GA G V++G +KN + VA+K +Q V RE E+++ +K
Sbjct: 44 YVFSEDRLLGEGAFGVVYKGEDKNTKQKVAIKQISQSKFQNDPIVLKNLKREIEIMQDLK 103
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
HENIV+L I++E C GG + +++ E +E + +T
Sbjct: 104 HENIVQLFNF--TYTASNVYIILEYCDGGDILSLMKKNEGKRFSEEIA-IKHFRQITEAF 160
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQE----EEQFVSLYGTEEY 182
K L ++HRD+KP NI+ + G K++DFG AR L + +Q ++ G+ Y
Sbjct: 161 KMLHSKGIIHRDIKPANILLH---KGIA--KISDFGFARMLDQTNLNSQQKLTALGSPLY 215
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P + + + F + D+WS+GV Y + G+ P+
Sbjct: 216 MSPQILSQ--------EQFSSKCDIWSLGVMFYEMIYGRTPW 249
>UniRef50_Q56UN5 Cluster: SPS1/STE20-related protein kinase YSK4;
n=19; Euteleostomi|Rep: SPS1/STE20-related protein kinase
YSK4 - Homo sapiens (Human)
Length = 1328
Score = 99.1 bits (236), Expect = 3e-19
Identities = 79/245 (32%), Positives = 120/245 (48%), Gaps = 27/245 (11%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVK-----TFNQLSHMRPHDVQMRE 58
L+ E +W+ +LGKGA G V+ G+ + G+ +AVK T N+L+ + + E
Sbjct: 1053 LKSEEPILWTKGEILGKGAYGTVYCGLT-SQGQLIAVKQVALDTSNKLAAEKEYRKLQEE 1111
Query: 59 FEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLL 117
++LK +KH NIV L ++ I ME GGS+ +I+ N +G L E F
Sbjct: 1112 VDLLKALKHVNIVAYLGTCLQENTVS--IFMEFVPGGSISSII----NRFGPLPEMVFCK 1165
Query: 118 VLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY 177
+ + G+ +L +N +VHRD+K N+M T KL DFG AR L + L
Sbjct: 1166 YTKQILQGVAYLHENCVVHRDIKGNNVMLM----PTGIIKLIDFGCARRL----AWAGLN 1217
Query: 178 GTEEYLHPDMYERAVLRKP--VGKS-FGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKE 234
GT + M+ P + +S +G D+WSIG T++ +ATG+ P
Sbjct: 1218 GTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGK---PPLASMDRMA 1274
Query: 235 TMFYI 239
MFYI
Sbjct: 1275 AMFYI 1279
>UniRef50_Q24HI1 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 650
Score = 98.7 bits (235), Expect = 3e-19
Identities = 68/211 (32%), Positives = 109/211 (51%), Gaps = 23/211 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR----EFEVLKKVKHENIVKL 73
LGKG+ G+V++ + +G+ A+K ++ S+M+ + E E +K + N VKL
Sbjct: 52 LGKGSFGSVYKA--EKDGKTYALKMISK-SYMKDRPFLRKYIQNEIESMKSINCVNCVKL 108
Query: 74 LAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
E VME C G+LFN+L +N GL E E L+ + G+K + +
Sbjct: 109 YDYFETNLAH--FFVMEYCAEGNLFNLLHS-KNGQGLPENEALVYFSQILNGLKTIHEKG 165
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVL 193
+HRDLKP NI+ + N K+ DFG AR L E ++ GT EY+ P+++++
Sbjct: 166 YMHRDLKPENILIHNN-----VAKICDFGFARPLGFNELTTTVCGTAEYMPPELHQQ--- 217
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + D+W++GV LY + G LPF
Sbjct: 218 -----QPYDYKADIWALGVLLYVMVFGHLPF 243
>UniRef50_Q17G02 Cluster: Inhibitor of nuclear factor kappa B kinase
beta subunit; n=5; Culicidae|Rep: Inhibitor of nuclear
factor kappa B kinase beta subunit - Aedes aegypti
(Yellowfever mosquito)
Length = 793
Score = 98.7 bits (235), Expect = 3e-19
Identities = 78/261 (29%), Positives = 121/261 (46%), Gaps = 28/261 (10%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQL---SHMRPHDVQMREFEV---LKKV 65
W LG G G V N E VA+K + L S M + + EV + KV
Sbjct: 14 WHREKRLGSGGFGFVTLWKNHKTNEMVAIKKCHILLDKSEMTDKNCERWCNEVSLMMNKV 73
Query: 66 KHENIVKLLAIEEE---QE------GRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFL 116
++ENIV+ + ++ E QE + ++ ME C GG L +L+ + GL+E E
Sbjct: 74 RNENIVRTVRVQPETFLQELIKHSTNKLPILCMEYCEGGDLRRVLNRVSSCSGLKELEVR 133
Query: 117 LVLEHLTAGMKHLRDNNLVHRDLKPGNI-MKYINEDGTTTYKLTDFGAARELQEEEQFVS 175
+L L + +L + + HRD+KP NI +K + + YKLTD G A+ L ++ S
Sbjct: 134 EILRSLRNAISYLHNLRITHRDIKPENIVLKQMGD--RMVYKLTDLGYAKALDKQSLNAS 191
Query: 176 LYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKET 235
L GT EY+ PD+ + +VD WS+G+ + + G PF P+ +
Sbjct: 192 LVGTVEYIAPDLI--------YCDRYNCSVDYWSMGIIAFEIICGIRPFSPHS--IVAKW 241
Query: 236 MFYITTKKASGVISGTQTTEN 256
M + KK+S + EN
Sbjct: 242 MMLVQQKKSSHIAITEDNREN 262
>UniRef50_Q2UCX8 Cluster: Serine/threonine protein kinase Chk2 and
related proteins; n=3; Eurotiomycetidae|Rep:
Serine/threonine protein kinase Chk2 and related
proteins - Aspergillus oryzae
Length = 701
Score = 98.7 bits (235), Expect = 3e-19
Identities = 76/272 (27%), Positives = 125/272 (45%), Gaps = 26/272 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR---EFEVLKKVKHE 68
++ T +GKGA V++ K +G A K ++ M+ + + E +++K +KH
Sbjct: 238 YNVTGQIGKGAFATVYKLATKQHGAVYAAKELDKRRFMKNGVLDQKVDNEMKIMKDLKHP 297
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
NIV+ + E + R I+ME GG L L ++T + E + + +++
Sbjct: 298 NIVQYMDHHEHE--RWIYIIMEYVPGGELSTYL---QSTGKIPEDMVKTIARQVLHALQY 352
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP--- 185
L + HRD+KP NI+ I+ KL+DFG ++ +QEE + GT Y P
Sbjct: 353 LHTRKITHRDIKPDNIL--ISSLDPLRVKLSDFGLSKVVQEETFLKTFCGTLLYCAPEVY 410
Query: 186 ---DMYERAVLRK--------PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKE 234
D Y R +RK P + +VD+WS+G LYH+ G P+ G R +
Sbjct: 411 PEYDSYRRGEVRKRRRLGDPPPKTSPYSQSVDMWSLGAVLYHILAGVPPYMGRGDDRGAQ 470
Query: 235 TMFYI-TTKKASGVISGTQTTENGPIDWAREL 265
+ I TT ++ +E G ID+ L
Sbjct: 471 MLRTIMTTDPDVDILRNEGVSEEG-IDFVTRL 501
>UniRef50_UPI0000DA406D Cluster: PREDICTED: similar to
serine/threonine kinase; n=6; Murinae|Rep: PREDICTED:
similar to serine/threonine kinase - Rattus norvegicus
Length = 739
Score = 98.3 bits (234), Expect = 5e-19
Identities = 68/221 (30%), Positives = 106/221 (47%), Gaps = 18/221 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LGKG+ V + + G VAVK + + V M E +++K + H NI+KL +
Sbjct: 25 LGKGSFAEVKLACHLHTGVWVAVKVLERGE--KNDSVIMTEIDIIKSLDHPNIIKLFHVI 82
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E +E +VME GG L + + E LQE E + + + + +N++ HR
Sbjct: 83 ESRERT--YMVMEHAAGGDLVSHI---EKVGCLQEEETHRIFTQMVRAVSYCHENSIAHR 137
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP NI+ DG + KL DFG A ++ ++F GT EY P+++
Sbjct: 138 DIKPDNILL----DGNGSVKLCDFGLAIKVTSGQRFKGFCGTLEYCAPEIFTDVEYDAQA 193
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFY 238
D+WS+GV LY + TG+ PF + KE M +
Sbjct: 194 N-------DIWSMGVVLYTMVTGRFPFEAKTYSQMKEKMLH 227
>UniRef50_Q4SMN8 Cluster: Chromosome undetermined SCAF14546, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14546, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 529
Score = 98.3 bits (234), Expect = 5e-19
Identities = 65/215 (30%), Positives = 109/215 (50%), Gaps = 15/215 (6%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHEN 69
Y + VLG G G V + + ++G +A K S + +V E +V+ ++ H N
Sbjct: 26 YTINREEVLGGGRFGQVHKCMENSSGLMLAAKIIKARSQ-KEKEVVRNEIQVMNQLNHAN 84
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
+++L A E + ++VME GG LF+ + D EN Y L E + +L + + G++++
Sbjct: 85 LIQLYAAFESRHDF--ILVMEYVEGGELFDRIID-EN-YNLTELDTVLFIRQICEGLQYM 140
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189
++H DLKP NI+ +N T K+ DFG AR + E+ +GT E+L P++
Sbjct: 141 HKMYILHLDLKPENIL-CVNR-ATNKIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVIN 198
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P D+WS+GV Y + +G PF
Sbjct: 199 YEFVSFP--------TDMWSLGVITYMLLSGLSPF 225
>UniRef50_A2EUZ8 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 965
Score = 98.3 bits (234), Expect = 5e-19
Identities = 70/210 (33%), Positives = 107/210 (50%), Gaps = 22/210 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKLLA 75
+G+G+ G VF+ K G VA+KT Q +M+ D+ RE ++LKKV H NI++LL
Sbjct: 10 IGEGSFGRVFKARRKYTGRMVAIKTI-QKGNMKDEDLVNFRREVDILKKVDHPNIMRLLE 68
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
E +V EL G LF I+ D T L E + + L + + HL ++
Sbjct: 69 YFETDSEF--CLVTELGRG-DLFQIISD---TQRLPEEQLKPIAAQLVSALNHLHQKKII 122
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAVLR 194
HRDLKP NI+ N ++ KL DFG AR L + S+ GT Y+ P++ +
Sbjct: 123 HRDLKPQNILVSDN----SSIKLCDFGFARALSRTTLVLNSIKGTPLYMAPELVQE---- 174
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ +D+WS+G+ LY + G+ P+
Sbjct: 175 ----YPYTEKIDIWSLGIILYELYYGKPPY 200
>UniRef50_A0E675 Cluster: Chromosome undetermined scaffold_8, whole
genome shotgun sequence; n=5; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_8,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 627
Score = 98.3 bits (234), Expect = 5e-19
Identities = 66/216 (30%), Positives = 106/216 (49%), Gaps = 20/216 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKVKHEN 69
+ LG G G V G+++ GE VA+K + + DV+ RE +LK ++H +
Sbjct: 28 YQLVKTLGVGTFGLVKLGLHQITGEKVAIKILEKERIIEVADVERVSREIHILKLIRHRH 87
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
+++L I E + + +VME C G LF+ + E L E E + + L +G++++
Sbjct: 88 VIQLYEIIETK--KHIFLVMEFCDNGELFDYIVKNEK---LDEIEACRIFQELISGIEYI 142
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189
N+VHRDLKP N++ D K+ DFG + ++ E + G+ Y P+M
Sbjct: 143 HKLNIVHRDLKPENLLL----DHQNQIKIVDFGLSNTYKQGELLKTACGSPCYAAPEMI- 197
Query: 190 RAVLRKPVGKSF-GATVDLWSIGVTLYHVATGQLPF 224
G + VD+WS GV L+ GQLPF
Sbjct: 198 -------AGHRYQSILVDIWSCGVILFATICGQLPF 226
>UniRef50_Q15139 Cluster: Serine/threonine-protein kinase D1; n=54;
Coelomata|Rep: Serine/threonine-protein kinase D1 - Homo
sapiens (Human)
Length = 912
Score = 98.3 bits (234), Expect = 5e-19
Identities = 68/209 (32%), Positives = 104/209 (49%), Gaps = 14/209 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLA 75
VLG G G V+ G ++ G VA+K ++L + Q+R E +L+ + H +V L
Sbjct: 588 VLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNLHHPGVVNLEC 647
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E E +VME G L IL + L E+ ++ + ++HL N+V
Sbjct: 648 MFETPER--VFVVMEKLHGDMLEMILSSEKGR--LPEHITKFLITQILVALRHLHFKNIV 703
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
H DLKP N++ + D KL DFG AR + E+ S+ GT YL P+ VLR
Sbjct: 704 HCDLKPENVL-LASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPE-----VLR- 756
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + ++D+WS+GV +Y +G PF
Sbjct: 757 --NKGYNRSLDMWSVGVIIYVSLSGTFPF 783
>UniRef50_UPI00004998A1 Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 434
Score = 97.9 bits (233), Expect = 6e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 14/208 (6%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHD-VQMREFEVLKKVKHENIVKLLAI 76
LG G V++ + K+ VA+K NQ D + RE E++KK++HEN+V
Sbjct: 145 LGDGQYSKVYKAIIKSTNSVVALKILNQTRERFTLDEISRRELEIMKKIQHENVVSFREC 204
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E ++ + ++ C G LF+ + T + E+E + L GM +L +++H
Sbjct: 205 FETKQNT--IFEVDFCEGADLFSRII---TTGKMDEHEGAFIFMQLLEGMNYLHSQHIIH 259
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP NI+ N+ T K+ DFG A+ Q + GT +Y P++ +L
Sbjct: 260 RDLKPENILLKENKP-YPTIKIADFGMAKIAQ---YGTTSCGTTQYAAPEV----ILPTS 311
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ D+WSIG+ LY + +G PF
Sbjct: 312 GRLQYTKECDIWSIGIILYIILSGTHPF 339
>UniRef50_Q4SFY0 Cluster: Chromosome 7 SCAF14601, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 7
SCAF14601, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 595
Score = 97.9 bits (233), Expect = 6e-19
Identities = 72/213 (33%), Positives = 105/213 (49%), Gaps = 23/213 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM---REFEVLKKVKHENIVKLL 74
LG+G+ V +G++ GE VAVK ++ + V RE + + ++H NI +LL
Sbjct: 51 LGEGSFAKVREGLHALTGEKVAVKVIDKRKAKKDSYVTKNLRREGHIQQMIRHPNITQLL 110
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
I E + +VMELC GG+L N + D + L E E + L ++HL +
Sbjct: 111 DILETENSY--YLVMELCPGGNLMNRIYDKKR---LDERETQKYIRQLVLAVEHLHRAGV 165
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFG---AARELQEEEQFVSLYGTEEYLHPDMYERA 191
VHRDLK N++ D KL DFG A L + F + G+ Y P++ R
Sbjct: 166 VHRDLKIENLLL----DEQDNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLSR- 220
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K +G VD+WSIGV +Y + TG LPF
Sbjct: 221 -------KKYGPKVDVWSIGVNMYAMLTGTLPF 246
>UniRef50_Q54TA3 Cluster: Putative uncharacterized protein mrkC;
n=1; Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein mrkC - Dictyostelium discoideum
AX4
Length = 773
Score = 97.9 bits (233), Expect = 6e-19
Identities = 67/210 (31%), Positives = 108/210 (51%), Gaps = 18/210 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTF--NQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
LG G G V G N E VA+K N+LS + + RE +++K + H NIVKLL
Sbjct: 52 LGNGTFGKVKLGTNICTKENVAIKFIKNNKLSG-KQKETCFREIDIMKLLDHPNIVKLLD 110
Query: 76 IEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
+ +++E G +++E +GG LF+ + E ++E E + + +++ N +
Sbjct: 111 VVDKREEEGTTYLIVEYVSGGELFDYIVAREY---IKEKEARKFFRQMISAIEYCHANLI 167
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
VHRDLKP N++ N D K++DFG + +Q + S G+ Y P++ +
Sbjct: 168 VHRDLKPENLLLDSNGD----IKISDFGLSNNIQPGKLLESFCGSPLYAAPEILKAE--- 220
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K G VD+WS+GV +Y V G LP+
Sbjct: 221 ----KYLGPPVDIWSLGVIMYAVLCGNLPW 246
>UniRef50_A3FQ16 Cluster: Calmodulin-domain protein kinase 1,
putative; n=3; Apicomplexa|Rep: Calmodulin-domain
protein kinase 1, putative - Cryptosporidium parvum Iowa
II
Length = 538
Score = 97.9 bits (233), Expect = 6e-19
Identities = 68/214 (31%), Positives = 111/214 (51%), Gaps = 16/214 (7%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHM-RPHDVQMREFEVLKKVKHENI 70
++ +LGKG+ G V + ++ + AVK N+ S + +RE E+LKK+ H NI
Sbjct: 76 YNIVCMLGKGSFGEVLKCKDRITQQEYAVKVINKASAKNKDTSTILREVELLKKLDHPNI 135
Query: 71 VKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLR 130
+KL I E+ IV EL TGG LF D+ E++ +++ + +G+ ++
Sbjct: 136 MKLFEILEDSSSF--YIVGELYTGGELF---DEIIKRKRFSEHDAARIIKQVFSGITYMH 190
Query: 131 DNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYER 190
+N+VHRDLKP NI+ +++ K+ DFG + Q+ + GT Y+ P+
Sbjct: 191 KHNIVHRDLKPENIL-LESKEKDCDIKIIDFGLSTCFQQNTKMKDRIGTAYYIAPE---- 245
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
VLR ++ D+WS GV LY + +G PF
Sbjct: 246 -VLR----GTYDEKCDVWSAGVILYILLSGTPPF 274
>UniRef50_Q9BZL6 Cluster: Serine/threonine-protein kinase D2; n=19;
Coelomata|Rep: Serine/threonine-protein kinase D2 - Homo
sapiens (Human)
Length = 878
Score = 97.9 bits (233), Expect = 6e-19
Identities = 68/210 (32%), Positives = 106/210 (50%), Gaps = 16/210 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLA 75
VLG G G V+ G ++ G VAVK ++L + Q+R E +L+ ++H IV L
Sbjct: 556 VLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLEC 615
Query: 76 IEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E E KV +VME G L IL + + +FL+ + ++HL N+
Sbjct: 616 MFETPE---KVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLIT--QILVALRHLHFKNI 670
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
VH DLKP N++ + D KL DFG AR + E+ S+ GT YL P++
Sbjct: 671 VHCDLKPENVL-LASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVL------ 723
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + + ++D+WS+GV +Y +G PF
Sbjct: 724 --LNQGYNRSLDMWSVGVIMYVSLSGTFPF 751
>UniRef50_UPI00004D6BBB Cluster: Protein kinase C, nu type (EC
2.7.1.-) (nPKC-nu) (Protein kinase EPK2).; n=1; Xenopus
tropicalis|Rep: Protein kinase C, nu type (EC 2.7.1.-)
(nPKC-nu) (Protein kinase EPK2). - Xenopus tropicalis
Length = 772
Score = 97.5 bits (232), Expect = 8e-19
Identities = 72/209 (34%), Positives = 106/209 (50%), Gaps = 14/209 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLA 75
VLG G G V+ G ++ G VA+K ++L + Q+R E +L+ ++ +V L A
Sbjct: 485 VLGSGQFGIVYGGKHRKTGRDVAIKVIDKLRFPSRQESQLRNEVAILQNLRFHGVVDLEA 544
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E E +VME G L IL + + F LV + LTA ++HL N+V
Sbjct: 545 MCETPE--RIFVVMEKLHGDMLEMILSSDKGKLPERITRF-LVTQILTA-LQHLHSKNIV 600
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
H DLKP N++ ED KL DFG AR + E+ S+ GT YL P+ VLR
Sbjct: 601 HCDLKPENVL-LATEDPFPQIKLCDFGFARIIGEKSFRRSVVGTPAYLAPE-----VLR- 653
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ ++D+WS+GV +Y +G PF
Sbjct: 654 --NSGYNRSLDMWSVGVIIYVSLSGTFPF 680
>UniRef50_Q7XTK4 Cluster: Putative mitogen-activated protein kinase
1; n=1; Medicago sativa|Rep: Putative mitogen-activated
protein kinase 1 - Medicago sativa (Alfalfa)
Length = 592
Score = 97.5 bits (232), Expect = 8e-19
Identities = 67/219 (30%), Positives = 116/219 (52%), Gaps = 22/219 (10%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQL---SHMRPHDVQMR-EFEVLKKVKH 67
W +LG+G+ G V++G++++ G AVK + L S + VQ+ E +L + +H
Sbjct: 320 WQKGELLGRGSFGTVYEGISED-GFFFAVKQVSLLDQGSQGKQSVVQLEHEIALLSQFEH 378
Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
ENIV+ + E ++ I +E T GSL ++ Y L++ + + G+K
Sbjct: 379 ENIVRYIGTEMDESNL--YIFIEFVTKGSLLSLY----RRYKLRDSQVSAYTRQILHGLK 432
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
+L D N+VHRD+K NI+ D + K+ DFG A+ ++ + S GT ++ P+
Sbjct: 433 YLHDRNIVHRDIKCANIL----VDANGSVKVADFGLAKAIKLND-VKSCQGTAFWMAPE- 486
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRP 226
V+R V K +G D+WS+G T+ + TG++P+ P
Sbjct: 487 ----VVRGKV-KGYGLPADIWSLGCTVLEMLTGKIPYSP 520
>UniRef50_A2FMG9 Cluster: AGC family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 417
Score = 97.5 bits (232), Expect = 8e-19
Identities = 68/212 (32%), Positives = 110/212 (51%), Gaps = 19/212 (8%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQ--LSHMRPHDVQMREFEVLKKVKHENIVKL 73
SVLG+G G V +K G+ A+K+ ++ L M+ D M E ++LK K IV L
Sbjct: 107 SVLGRGFYGKVVLAKHKKTGKFCAIKSIHKKVLLDMKKVDTIMVERDILKSTKSPFIVSL 166
Query: 74 LAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
L+ Q +V+E +GG LF L + N + + + L + L ++ L ++
Sbjct: 167 LS--SFQTPSKFYLVLEYVSGGDLFMHLTNNNNEISVDQIK--LYIAELAVALEQLHKDH 222
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVS-LYGTEEYLHPDMYERAV 192
+++RDLKP N++ I EDG KLTDFG ++ L E++ + L GT EYL P++
Sbjct: 223 IIYRDLKPENVL--ICEDGHI--KLTDFGISKMLNEKQSTTNTLCGTGEYLAPEVIS--- 275
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + +D W +G+ +Y + G+ PF
Sbjct: 276 -----DKGYTEAIDWWQLGILMYEMVVGKTPF 302
>UniRef50_A0E0N1 Cluster: Chromosome undetermined scaffold_72, whole
genome shotgun sequence; n=10; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_72,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 506
Score = 97.5 bits (232), Expect = 8e-19
Identities = 69/224 (30%), Positives = 111/224 (49%), Gaps = 27/224 (12%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVK-----TFNQLSHMRPHDVQMREFEVL 62
+ Y+++ +G+G+ VF+G N+ GE VA+K N ++R +Q E +++
Sbjct: 7 DKYIFNVKDRIGQGSYAEVFKGTNEKTGEKVAIKMLSKSVINADDYLREGLIQ--EIKIM 64
Query: 63 KKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHL 122
+K+K NIV+LL + E IV E C GG +L + L E E + L +
Sbjct: 65 QKLKSPNIVQLLDVME--TNNNYYIVQEYCDGGDFDELL---KKRKLLPEKEAIKFLVDV 119
Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ--EEEQFVSLYGTE 180
G L N ++HRDLKP NI+ I++ TYKL DFG A+ + ++ S+ GT
Sbjct: 120 LNGFTQLIKNGIIHRDLKPANIL--IDKQ---TYKLADFGFAKCVDNFKKTMMASMVGTP 174
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
Y+ P + + K + + D+WSIG Y G+ P+
Sbjct: 175 LYMSPQILDH--------KRYNSKTDVWSIGFIFYEALFGKTPW 210
>UniRef50_A0CQE0 Cluster: Chromosome undetermined scaffold_24, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_24,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 567
Score = 97.5 bits (232), Expect = 8e-19
Identities = 67/218 (30%), Positives = 109/218 (50%), Gaps = 19/218 (8%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ----MREFEVLKKVK 66
++ V+GKG V K N AVKTF + + M ++ Q + E ++L+
Sbjct: 145 IYLNLKVIGKGTYAKVLLAQRKQNQSKYAVKTFQKSALMDKNNKQRQGLLNEIDLLRSCD 204
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
H NI+KL I E G +VMEL GG LF+++ + T QE + L++ + +
Sbjct: 205 HPNIIKLYEIYES--GDYIYLVMELLEGGELFDLILE---TQCFQESKVALIMFKIFDAL 259
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPD 186
++L N++HRD+KP NI+ ++ K+ DFG A E ++ GT Y+ P+
Sbjct: 260 EYLHTKNIMHRDIKPENIL-LKDKSENFDLKIADFGLA-SYTEANLLITRCGTPGYVAPE 317
Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ E K + VD++S G+ LY + +GQ PF
Sbjct: 318 ILE--------DKKYNEKVDVFSAGIILYILLSGQAPF 347
>UniRef50_Q8IVW4 Cluster: Cyclin-dependent kinase-like 3; n=36;
Mammalia|Rep: Cyclin-dependent kinase-like 3 - Homo
sapiens (Human)
Length = 592
Score = 97.5 bits (232), Expect = 8e-19
Identities = 67/219 (30%), Positives = 116/219 (52%), Gaps = 22/219 (10%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENI 70
++ T +G+G+ G V + +KN G+ VA+K F + + + MRE + LK+ HEN+
Sbjct: 3 MYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENL 62
Query: 71 VKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPEN-TYGLQEYEFLLVLEHLTAGMKH 128
V L+ + +++ K+ +V E +LD+ ++ +GL+ L + + +
Sbjct: 63 VNLIEVFRQKK---KIHLVFEFID----HTVLDELQHYCHGLESKRLRKYLFQILRAIDY 115
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDM 187
L NN++HRD+KP NI+ +++ G T KL DFG AR L + Y T Y P++
Sbjct: 116 LHSNNIIHRDIKPENIL--VSQSGIT--KLCDFGFARTLAAPGDIYTDYVATRWYRAPEL 171
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRP 226
VL+ S+G VD+W++G + +ATG P+ P
Sbjct: 172 ----VLK---DTSYGKPVDIWALGCMIIEMATGN-PYLP 202
>UniRef50_Q10SI6 Cluster: Protein kinase domain containing protein,
expressed; n=4; Oryza sativa|Rep: Protein kinase domain
containing protein, expressed - Oryza sativa subsp.
japonica (Rice)
Length = 652
Score = 97.1 bits (231), Expect = 1e-18
Identities = 63/208 (30%), Positives = 103/208 (49%), Gaps = 13/208 (6%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+G G+ V+ + G+ VAVK + + R + E +L + H NI++L+
Sbjct: 35 IGVGSFAKVYLATHLRTGDVVAVKEIDPRRIDERVRGGILEEKAILSTLSHPNILRLIDT 94
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+E+ +++E C GG L L + + L G+K LR ++VH
Sbjct: 95 IQEEN---LYLILEYCNGGDLEGYRTKGGEDARLPDATARDFMRQLAEGLKMLRGRSIVH 151
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP N++ N D T K+ DFG AR L +E ++ G+ Y+ P+ ++R
Sbjct: 152 RDLKPQNLLLSTNGD-AITLKIGDFGFARSLVQENLAATMCGSPSYMAPE-----IMR-- 203
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + A DLWS+GV L+ + TG+LPF
Sbjct: 204 -CEDYDAKADLWSVGVILFQLVTGKLPF 230
>UniRef50_A0DXN2 Cluster: Chromosome undetermined scaffold_69, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_69,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 890
Score = 97.1 bits (231), Expect = 1e-18
Identities = 70/221 (31%), Positives = 108/221 (48%), Gaps = 16/221 (7%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN--QLSHMRPHDVQMREFEVLKK 64
S+ V+ VLG+G G V G +K GE VA+K + +L + D+ RE EV+K
Sbjct: 95 SQISVYQIMKVLGEGGFGKVMLGKHKVTGEQVAIKLIDSGKLWNAEDIDLVFREAEVMKN 154
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
++H NIVK+L + V++ME GG L L + GL E E ++ +
Sbjct: 155 LRHNNIVKILNCYTLPNMQ-VVLIMEFLQGGDLVEYLQEKG---GLSEQEARIIFRQIAE 210
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
+++ D L+HRDLK NI+ + K+ DFG A G+ Y+
Sbjct: 211 AIRYCHDKRLIHRDLKLENIL--LTSKVEKIIKIIDFGIATVSTNFTIDKVDRGSLSYMP 268
Query: 185 PD-MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P+ M +A+ KP ++D+W++GV LY + G LPF
Sbjct: 269 PELMSGQAIEIKP-------SIDIWALGVILYALVCGNLPF 302
>UniRef50_A0CJI6 Cluster: Chromosome undetermined scaffold_2, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_2,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 752
Score = 97.1 bits (231), Expect = 1e-18
Identities = 67/220 (30%), Positives = 112/220 (50%), Gaps = 22/220 (10%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVK--TFNQLSHMRPHDVQMREFEVLKKVK 66
NY +ST +V+G+G+ G V+ G N ++G+ VA+K F Q S +Q +E +++K +
Sbjct: 19 NYAFSTQAVIGRGSYGVVYIGRNIDSGQIVAIKAIAFQQYSSENQTLLQ-KEIDIMKDLD 77
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
NIV+L I+ I+ ELCTGG L + + + ++E +L + G+
Sbjct: 78 CPNIVRL--IDVITTANNCYIISELCTGGDLKEYM---KRSGPIEESAATKILIQILRGI 132
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ--EEEQFVSLYGTEEYLH 184
++HRDLKP NI+ N +K+ DFG A+ +E+ SL GT Y+
Sbjct: 133 LQSFKRGIIHRDLKPANILVANN----NIFKIADFGFAKRFDKLDEDLMTSLVGTPLYMS 188
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P + R + + + D+WSIG+ Y + G+ P+
Sbjct: 189 PQVLLR--------RQYTSKCDVWSIGLIFYEMIEGKTPW 220
>UniRef50_A0BUI0 Cluster: Chromosome undetermined scaffold_129,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_129,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 512
Score = 97.1 bits (231), Expect = 1e-18
Identities = 63/208 (30%), Positives = 105/208 (50%), Gaps = 16/208 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ-MREFEVLKKVKHENIVKLLAI 76
LG G+ V +GV+K G A+K ++ + + E E+LK++ H NIVK+L I
Sbjct: 77 LGSGSYAEVRKGVHKVLGITRAIKIISKTEATNEEVSRVLHEAEILKQLDHPNIVKILEI 136
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
Q + IV ELCTGG LF+ + + + E + +++ + G+ + + +VH
Sbjct: 137 Y--QNAQQIFIVTELCTGGELFDAIVESQQ---FSEKDAAKLMKQVLQGLNYCHQHKIVH 191
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RD+KP NI+ + ++D T K+ DFG +R ++ GT Y+ P++ +
Sbjct: 192 RDIKPENIV-FESKDKKGTIKIIDFGTSRVFDPHQKMNQKIGTPYYIAPEVLK------- 243
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + D+WS GV Y + G PF
Sbjct: 244 --KKYDEKCDIWSCGVLTYILLCGYPPF 269
>UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin -
Caenorhabditis elegans
Length = 6048
Score = 96.7 bits (230), Expect = 1e-18
Identities = 67/220 (30%), Positives = 102/220 (46%), Gaps = 20/220 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLL-AI 76
LG GA G V + + G A K F H + +E + + ++H +V L A
Sbjct: 5157 LGTGAFGVVHRVTERATGNNFAAK-FVMTPHESDKETVRKEIQTMSVLRHPTLVNLHDAF 5215
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E++ E V++ E +GG LF + D N + E E + + + G+ H+ +NN VH
Sbjct: 5216 EDDNE---MVMIYEFMSGGELFEKVADEHNK--MSEDEAVEYMRQVCKGLCHMHENNYVH 5270
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
DLKP NIM + KL DFG L ++ GT E+ P++ E
Sbjct: 5271 LDLKPENIM--FTTKRSNELKLIDFGLTAHLDPKQSVKVTTGTAEFAAPEVAE------- 5321
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETM 236
GK G D+WS+GV Y + +G P+GG + ET+
Sbjct: 5322 -GKPVGYYTDMWSVGVLSYILLSG---LSPFGGENDDETL 5357
>UniRef50_Q4DSQ1 Cluster: Protein kinase, putative; n=2; Trypanosoma
cruzi|Rep: Protein kinase, putative - Trypanosoma cruzi
Length = 547
Score = 96.7 bits (230), Expect = 1e-18
Identities = 66/224 (29%), Positives = 120/224 (53%), Gaps = 24/224 (10%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVK--TFNQLSHMRPHDVQMREFEVLKKVKHENIVKL 73
+++GKG+ G VFQ ++++ +AVK +F++ S + +E +LK + H +IVK
Sbjct: 219 ALIGKGSFGVVFQAMDRDTNHIIAVKEISFSEGSESKALKAVRKELALLKLLDHPHIVKC 278
Query: 74 LAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDN 132
L EE E I ME +GGS+ ++L T+G E + + + G+++L
Sbjct: 279 LG--EECEESCLRIYMEYVSGGSISSVL----RTFGPFHEKQASIYTRQMLEGLEYLHSK 332
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAV 192
N++HRDLK N++ ++ +G T K++DFG A++L + +L GT ++ P++
Sbjct: 333 NIMHRDLKGDNLL--VDPNG--TLKISDFGTAKDLLDPTASTALAGTAYFMAPEVI---- 384
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETM 236
+ + G D+WS+G + + TG PF G +N+ +M
Sbjct: 385 ----LSQGVGLPSDVWSVGCCVIEMLTGSPPF---SGVKNQYSM 421
>UniRef50_Q86YV6 Cluster: Uncharacterized serine/threonine-protein
kinase SgK085; n=33; Euteleostomi|Rep: Uncharacterized
serine/threonine-protein kinase SgK085 - Homo sapiens
(Human)
Length = 388
Score = 96.7 bits (230), Expect = 1e-18
Identities = 64/215 (29%), Positives = 104/215 (48%), Gaps = 15/215 (6%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHEN 69
Y S T +LG G G V + G +A K M+ + E V+ ++ H N
Sbjct: 104 YTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRG-MKDKEEVKNEISVMNQLDHAN 162
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
+++L E + V+VME GG LF+ + D +Y L E + +L ++ + G++H+
Sbjct: 163 LIQLYDAFESKNDI--VLVMEYVDGGELFDRIID--ESYNLTELDTILFMKQICEGIRHM 218
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189
++H DLKP NI+ +N D K+ DFG AR + E+ +GT E+L P++
Sbjct: 219 HQMYILHLDLKPENIL-CVNRD-AKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVN 276
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P D+WS+GV Y + +G PF
Sbjct: 277 YDFVSFP--------TDMWSVGVIAYMLLSGLSPF 303
>UniRef50_Q9C098 Cluster: Serine/threonine-protein kinase DCLK3;
n=13; Eumetazoa|Rep: Serine/threonine-protein kinase
DCLK3 - Homo sapiens (Human)
Length = 648
Score = 96.7 bits (230), Expect = 1e-18
Identities = 65/228 (28%), Positives = 112/228 (49%), Gaps = 17/228 (7%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
+ T V+G G V + ++ + A+K ++ D+ E +++ + H NIV
Sbjct: 356 YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIV 415
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KL + E +++E GG LF+ + + + E + L++ L + H+ D
Sbjct: 416 KLHEVYETD--MEIYLILEYVQGGDLFDAIIE---SVKFPEPDAALMIMDLCKALVHMHD 470
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERA 191
++VHRDLKP N++ NED +TT KL DFG A+ + ++ GT Y+ P++
Sbjct: 471 KSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHV--VRPIFTVCGTPTYVAPEILSE- 527
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
K +G VD+W+ GV LY + G PFR R+++ +F I
Sbjct: 528 -------KGYGLEVDMWAAGVILYILLCGFPPFR--SPERDQDELFNI 566
>UniRef50_Q9JLM8 Cluster: Serine/threonine-protein kinase DCLK1;
n=15; Euteleostomi|Rep: Serine/threonine-protein kinase
DCLK1 - Mus musculus (Mouse)
Length = 756
Score = 96.7 bits (230), Expect = 1e-18
Identities = 66/220 (30%), Positives = 109/220 (49%), Gaps = 17/220 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V + + ++ A+K + + E +L++VKH NIV L IE
Sbjct: 412 IGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV--LLIE 469
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E +VMEL GG LF+ + +T E + +L +L + +K+L N+VHR
Sbjct: 470 EMDVPTELYLVMELVKGGDLFDAIT---STSKYTERDASGMLYNLASAIKYLHSLNIVHR 526
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP N++ Y ++DG+ + KL DFG A + + ++ GT Y+ P++
Sbjct: 527 DIKPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET------ 578
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
+G VD+W+ GV Y + G PFR G ++E +F
Sbjct: 579 --GYGLKVDIWAAGVITYILLCGFPPFR--GSGDDQEVLF 614
>UniRef50_UPI00006CDDE2 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 794
Score = 96.3 bits (229), Expect = 2e-18
Identities = 69/215 (32%), Positives = 113/215 (52%), Gaps = 26/215 (12%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
+LGKG G V G NKN GE VAVK Q + + + E ++LK+++H+NIV+
Sbjct: 158 ILGKGTFGTVVLGHNKNTGEIVAVKLIETQYDRKQKYKSIIDEVKILKQMRHKNIVRYYG 217
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT---AGMKHLRDN 132
I+E + IV E +GGSL+ ++ +G ++ L+ ++ T G+++L +
Sbjct: 218 IQEHKAKDHIGIVCEYVSGGSLWRLI----QKFG--KFSEPLIRKYTTDILYGLQYLHYH 271
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ---EEEQFVSLYGTEEYLHPDMYE 189
+ HRD+K NI+ ++ DG KL DFG A+ + +E Q GT ++ P++
Sbjct: 272 GITHRDIKGANIL--VDSDGVC--KLADFGLAKSISQEIDEGQLKLPQGTPNWMAPEVCR 327
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
R F D+WS+G T+Y + TG+ PF
Sbjct: 328 SGTCR------FS---DIWSLGCTVYEMITGKPPF 353
>UniRef50_Q2JQG2 Cluster: Serine/threonine protein kinase; n=2;
Synechococcus|Rep: Serine/threonine protein kinase -
Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria
bacteriumYellowstone A-Prime)
Length = 643
Score = 96.3 bits (229), Expect = 2e-18
Identities = 64/206 (31%), Positives = 101/206 (49%), Gaps = 14/206 (6%)
Query: 19 GKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIEE 78
G+G G VF ++ G+ VA+K P+ +RE L + H NI + A+E
Sbjct: 28 GQGQYGRVFCARPRHGGDLVALKELPAERFPTPN--LLRELRYLLTLNHPNITRCYALEH 85
Query: 79 EQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRD 138
+EGR +V+E C GG+L ++D E L + L ++ + AG+ H ++H D
Sbjct: 86 AREGR--YLVLEYCEGGTLRELIDQVERGLWLPVKQVLGFVDQILAGLDHAHRQGVIHCD 143
Query: 139 LKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPVG 198
+KP NI+ G KLTDFG AR Q +S G+ Y+ P+ + G
Sbjct: 144 VKPENILLKPTPQG-WQLKLTDFGIARHPQPAPGEISATGSPAYMAPERF--------YG 194
Query: 199 KSFGATVDLWSIGVTLYHVATGQLPF 224
+ F DL+++G+ L + TG+ PF
Sbjct: 195 Q-FSPASDLYAVGIILLELLTGRRPF 219
>UniRef50_Q6BG36 Cluster: SNF1-related protein kinase, putative;
n=2; Oligohymenophorea|Rep: SNF1-related protein kinase,
putative - Paramecium tetraurelia
Length = 422
Score = 96.3 bits (229), Expect = 2e-18
Identities = 65/216 (30%), Positives = 106/216 (49%), Gaps = 20/216 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKVKHEN 69
+ LG G G V G+++ GE VA+K + + DV+ RE +LK ++H +
Sbjct: 28 YQLVKTLGVGTFGLVKLGLHQITGEKVAIKILEKERIVEVADVERVSREIHILKLIRHRH 87
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
+++L I E + + +VME C G LF+ + + L E E + + L +G++++
Sbjct: 88 VIQLYEIIETK--KHIFLVMEFCDKGELFDYIVKNDK---LDEIEACRIFQELISGIEYI 142
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189
N+VHRDLKP N++ D K+ DFG + ++ E + G+ Y P+M
Sbjct: 143 HKLNIVHRDLKPENLLL----DHQNQIKIVDFGLSNTYKQGELLKTACGSPCYAAPEMI- 197
Query: 190 RAVLRKPVGKSF-GATVDLWSIGVTLYHVATGQLPF 224
G + VD+WS GV L+ GQLPF
Sbjct: 198 -------AGHRYQSILVDIWSCGVILFATICGQLPF 226
>UniRef50_Q240Z4 Cluster: Protein kinase domain containing protein;
n=4; Eukaryota|Rep: Protein kinase domain containing
protein - Tetrahymena thermophila SB210
Length = 550
Score = 96.3 bits (229), Expect = 2e-18
Identities = 63/221 (28%), Positives = 109/221 (49%), Gaps = 23/221 (10%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDV---QMREFEVLKKV 65
+Y W +G+G+ G V++ N + VAVK + + + + D+ E +++K++
Sbjct: 9 DYQWENRKFIGEGSFGKVYRATNTKTKQDVAVKVLD-MKNFKQQDMIASLKNEIQIMKQL 67
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
K NIV+LL + I ME C GG L + ++ L+E + + +L+ G
Sbjct: 68 KSPNIVRLLDCSGNT--KETFIFMEYCEGGDLKHYIEKKGGK--LKEKQAIDILKQFMNG 123
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEE-EQFVSLY-GTEEYL 183
K + + +HRD+KP NI+ T+K+ DFG A ++ +QF+ Y GT Y+
Sbjct: 124 FKEMHEKGYIHRDIKPQNILL-----SRETFKIADFGFATKVDPRGKQFMKEYVGTPLYM 178
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P + E + A D+WSIG+T Y + G+ P+
Sbjct: 179 APQLLE--------NMPYTAKSDVWSIGMTFYEIIFGKTPW 211
>UniRef50_A2F0J6 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 307
Score = 96.3 bits (229), Expect = 2e-18
Identities = 65/230 (28%), Positives = 112/230 (48%), Gaps = 20/230 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKVKHENIVKLLA 75
+GKG+ G + + K++ + VA+K N +M H+ +M E +LKK++++NIV
Sbjct: 16 IGKGSFGQAYIAIRKSDNKTVALKQINY-GNMSTHEKEMLVNECNILKKLRNDNIVTYYD 74
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK--HLRDNN 133
+ R ++ME C+GG L + + + G E + L L L + H
Sbjct: 75 RIVDTSQRTLFLIMEYCSGGDLQKFIQNSTSPIG--ENQIWLSLSELALALNECHNGKER 132
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVL 193
++HRD+KPGNI +I+ G KL DFG A+ + + L GT Y+ P++
Sbjct: 133 IIHRDIKPGNI--FIDSSGHV--KLGDFGLAKPIPDGSTKTYL-GTPLYMSPELVSH--- 184
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
S+ D+W++G +Y +A PFR YG ++ + Y ++
Sbjct: 185 -----HSYDDKSDIWALGCVIYEMAAKSPPFRAYGQQQLNGKIKYAEVRR 229
>UniRef50_A0E574 Cluster: Chromosome undetermined scaffold_79, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_79,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 319
Score = 96.3 bits (229), Expect = 2e-18
Identities = 72/253 (28%), Positives = 126/253 (49%), Gaps = 29/253 (11%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPH---DVQMREFEVLKKVK 66
YV++ V+G G +V++G ++N E VA+K ++ S ++ + E +LK V+
Sbjct: 47 YVYNLNDVIGTGEFSSVYKGQDQNTNETVAIKIIDRKSIQNNQIFRNLLVNEINILKSVE 106
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
++ ++KL E IV E C+ G L +I++ + Y L E+ + +L+HL +
Sbjct: 107 NKCLLKLFNYLETMNNI--YIVTEFCSDGDLQSIIE--KKGY-LPEHNAVKILKHLIKAL 161
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+L++ N+VHRD+K NI+ KL DFG A +L Q + + + GT Y+ P
Sbjct: 162 LYLKERNIVHRDIKTQNILV-----SNQIPKLADFGFAVDLNQPQTREILQIGTPLYMAP 216
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKAS 245
++Y + + DLW++G+ Y + G++PF + E MF + K
Sbjct: 217 EIYSH--------YQYTSKTDLWALGIVFYEMLYGKVPFNA-KNPKELEQMFQMHKK--- 264
Query: 246 GVISGTQTTENGP 258
+ T ENGP
Sbjct: 265 ---NQTIQYENGP 274
>UniRef50_A0CA86 Cluster: Chromosome undetermined scaffold_160,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_160,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 569
Score = 96.3 bits (229), Expect = 2e-18
Identities = 71/226 (31%), Positives = 111/226 (49%), Gaps = 23/226 (10%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVN-KNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK 66
E++V + LGKG G V+ + K + + K D +++ E L KV
Sbjct: 8 EDFVIKKSEFLGKGQYGVVYGCYSEKLKDQKLCAKVLQAQIEKGLIDREIKILEQLNKVD 67
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLL-----VLEH 121
+ N+VK+ + +E+ R IVME CTGG L ++D Y L + F L +
Sbjct: 68 NPNLVKIYRVIKEE--RQIYIVMERCTGGDLKQLMDQ----YQLSKKSFTLEQIQDIARQ 121
Query: 122 LTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQE--EEQFVSLYGT 179
+ G K L D ++HRD+KP NI+ N +G KLTDFG R L + ++Q ++ GT
Sbjct: 122 IILGYKSLFDIKVIHRDIKPANILIENNGNGQIIVKLTDFGMGRMLDDITKKQVLTKVGT 181
Query: 180 EEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVA-TGQLPF 224
Y P +Y + + + D++S+GV LY +A +LPF
Sbjct: 182 PAYAAPQLY--------LEDQYSSKCDVYSLGVILYQLAFNNRLPF 219
>UniRef50_A0BJR0 Cluster: Chromosome undetermined scaffold_110,
whole genome shotgun sequence; n=9; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_110,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 594
Score = 96.3 bits (229), Expect = 2e-18
Identities = 63/225 (28%), Positives = 111/225 (49%), Gaps = 16/225 (7%)
Query: 1 MSFLRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM-REF 59
+S +GS +ST S LG GA G V++ +K G A+K + S ++ ++ E
Sbjct: 136 ISLKQGSIGKFYSTGSTLGAGAYGKVWKVTHKTTGLIRAMKQIKKSSLIQEEQQRLFAEM 195
Query: 60 EVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVL 119
+LK + H +IVKL E Q+ + ++ E +GG LF + + E++
Sbjct: 196 NILKNLDHPHIVKLY--ELYQDAQNYYLITEYLSGGELFERIKAMTIFNEKKAAEYM--- 250
Query: 120 EHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGT 179
+ + + + + +VHRDLKP NI+ ++N+ T+ K+ DFG +R+ ++ GT
Sbjct: 251 RQILSAVMYCHEQKIVHRDLKPENIL-FVNDSSTSPLKIIDFGTSRKYDPSKKMTKKLGT 309
Query: 180 EEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
Y+ P++ + + + D+WS GV LY + G PF
Sbjct: 310 PYYIAPEVLK---------QDYNEKCDIWSCGVILYILLCGYPPF 345
>UniRef50_A7TJU8 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 977
Score = 96.3 bits (229), Expect = 2e-18
Identities = 59/210 (28%), Positives = 108/210 (51%), Gaps = 20/210 (9%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
+V+GKG+ G V++ VN+ + VA+K N + +D+ M E +LK + H NIVK
Sbjct: 67 AVIGKGSFGVVYKAVNRKTNQVVAIKEVNYDNDEELNDI-MSEIHLLKNLNHVNIVKYHG 125
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
++ + I++E C+ GSL ++ P G+ E E + G+ +L + ++
Sbjct: 126 FIQKMD--TLYIILEYCSRGSLKKLI-SPNR--GIPEIEAQSYIRQTLQGLSYLHEQGVI 180
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRD+K N++ D + KL DFG + ++ ++L G+ ++ P++
Sbjct: 181 HRDIKSANLLL----DSSNVVKLADFGVSTKVNNASMAMTLAGSLNWMAPEI-------- 228
Query: 196 PVGKSFGATV-DLWSIGVTLYHVATGQLPF 224
+G +T+ D+WS+G T+ + TG PF
Sbjct: 229 -IGNRGASTLSDIWSLGATVVELLTGNPPF 257
>UniRef50_P41892 Cluster: Cell division control protein 7; n=1;
Schizosaccharomyces pombe|Rep: Cell division control
protein 7 - Schizosaccharomyces pombe (Fission yeast)
Length = 1062
Score = 96.3 bits (229), Expect = 2e-18
Identities = 73/213 (34%), Positives = 111/213 (52%), Gaps = 29/213 (13%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKVKHENIVKLLA 75
LGKGA GAV++G+N NGE VAVK +LS M D+ + E ++LK + H NIVK
Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKV-KLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRG 73
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDD----PENTYGLQEYEFLLVLEHLTAGMKHLRD 131
Q I++E C GSL +I + PEN L ++ L G+ +L +
Sbjct: 74 --SYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVL-------QGLLYLHN 124
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERA 191
++HRD+K NI+ +DG T KL DFG A ++ E S+ G+ ++ P++ E
Sbjct: 125 QGVIHRDIKGANIL--TTKDG--TIKLADFGVATKINALEDH-SVVGSPYWMAPEVIEL- 178
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
VG + + D+WS+G T+ + G P+
Sbjct: 179 -----VGATTAS--DIWSVGCTVIELLDGNPPY 204
>UniRef50_A2AQX6 Cluster: Novel protein tyrosine kinase; n=2; Mus
musculus|Rep: Novel protein tyrosine kinase - Mus
musculus (Mouse)
Length = 640
Score = 95.9 bits (228), Expect = 2e-18
Identities = 74/222 (33%), Positives = 111/222 (50%), Gaps = 23/222 (10%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK 66
+E+Y TT LG+G G V + VA+K Q R + + E E++K +
Sbjct: 21 TEHYEILTT--LGQGTFGDVKLANHLVTQTKVAIKILPQ---NRKNPLVQPEIEIMKSLD 75
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAG 125
H +I+KLL I + R IV+E GG L N +++ +G L E E + + L
Sbjct: 76 HPHIIKLLHIIDTT--RNIFIVLEHAVGGELMNRIEE----FGYLAEVECHRLFKQLVYA 129
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
+++ + +VHRDLKP NI+ D KLTDFG ++ ++ V+ GT Y P
Sbjct: 130 LQYCHEKGIVHRDLKPENILL----DHRGNVKLTDFGLGTKIIMGQKLVTFCGTLPYCAP 185
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPY 227
+++E G G D+WS+GV LY +ATG LPF Y
Sbjct: 186 ELFEDR------GYD-GRATDVWSLGVVLYFMATGCLPFNGY 220
>UniRef50_Q9VE91 Cluster: CG7125-PA, isoform A; n=2; Diptera|Rep:
CG7125-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 836
Score = 95.9 bits (228), Expect = 2e-18
Identities = 68/210 (32%), Positives = 104/210 (49%), Gaps = 16/210 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLA 75
VLG G G V+ GV+K VA+K ++L + Q++ E +L+ + H +V L
Sbjct: 548 VLGSGQFGVVYGGVHKKTQREVAIKVIDKLRFPTKQEAQLKNEVAILQNISHCGVVNLER 607
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E E +VME G L IL + +FL+ + +K+L N+V
Sbjct: 608 MFETPE--RIFVVMEKLKGDMLEMILSHARGRLSERVTKFLIT--QILIALKYLHSQNIV 663
Query: 136 HRDLKPGNIMKYINEDGT-TTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
H DLKP N++ ++ D KL DFG AR + E+ S+ GT YL P+ VLR
Sbjct: 664 HCDLKPENVL--LSSDAEFPQVKLCDFGYARIIGEKSFRRSVVGTPAYLAPE-----VLR 716
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + ++D+WS+GV +Y +G PF
Sbjct: 717 ---NKGYNRSLDMWSVGVIIYVSLSGTFPF 743
>UniRef50_Q54SJ5 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 312
Score = 95.9 bits (228), Expect = 2e-18
Identities = 66/208 (31%), Positives = 109/208 (52%), Gaps = 18/208 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKV-KHENIVKLLAI 76
+G+GA V + ++ G VA+K+ N + + + MRE E++KKV H NI+KL +
Sbjct: 44 IGRGAFSIVREATSRATGTKVAIKSIN--TRFIKNKLLMREIEIMKKVGDHPNILKLYEV 101
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E + +V+EL TGG LF+ + Y Q+ ++ + + + HL N + H
Sbjct: 102 YETTKHLH--LVLELVTGGELFDKIVQ-RGEYSEQDAS--KIVRQIVSAVGHLHANGIAH 156
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP N++ E+G ++ DFG ++ + + + G+ EY+ P++ E KP
Sbjct: 157 RDLKPQNLL-CAGEEG-DDIRVADFGLSKIFGDGDYLETCCGSPEYVAPEVLE----CKP 210
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
K+ DLWS+GV Y + TG PF
Sbjct: 211 YDKA----CDLWSVGVITYVLLTGCFPF 234
>UniRef50_Q4DIT1 Cluster: Protein kinase, putative; n=4;
Trypanosoma|Rep: Protein kinase, putative - Trypanosoma
cruzi
Length = 1290
Score = 95.9 bits (228), Expect = 2e-18
Identities = 84/301 (27%), Positives = 132/301 (43%), Gaps = 19/301 (6%)
Query: 1 MSFLRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFE 60
M+ + ++ +TTS+LGKG G V+ N GE A+K + ++E E
Sbjct: 107 MTIIFEEDSLQLTTTSLLGKGGFGRVY-AARSNGGELYALKVSAKKLTEGDWARLLKEVE 165
Query: 61 VLKKV-KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVL 119
++ +H N+VK +A ++E +VME C SL +++ + +GL E L V
Sbjct: 166 LMNHFSRHPNVVKFIAAGRDEETA--YVVMECCASRSLHDVIAN----HGLDVPEILWVG 219
Query: 120 EHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGT 179
L + + +HRDLKP N++ + DG K+TDFG + + E + ++ GT
Sbjct: 220 WALVDTIAFMHSKGCIHRDLKPQNLL--FDFDGNL--KITDFGLSSRIAEAQPRKTVAGT 275
Query: 180 EEYLHPDMYERAVLRKPVGK-----SFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKE 234
Y+ P++ E R +G VD WSIGV +Y + T P+ +R
Sbjct: 276 AMYMAPEIAEAVYKRMSHSTHQPPLQYGQEVDTWSIGVVIYVMLTRMNPYMEAMEKRGTR 335
Query: 235 TMFYITTKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRI 294
M T K S + P W+ + P C L T A L EV H +
Sbjct: 336 EMDK-TQKTLSLFNAVADAAWEWPTGWSGD-PELCDLVNWALHRDTKKRATLQEVLQHPV 393
Query: 295 W 295
W
Sbjct: 394 W 394
>UniRef50_A0EAM0 Cluster: Chromosome undetermined scaffold_86, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_86,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 458
Score = 95.9 bits (228), Expect = 2e-18
Identities = 69/220 (31%), Positives = 108/220 (49%), Gaps = 22/220 (10%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVN-KNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKK 64
++Y + S +G GA V+ G + N+ VA+K + + Q RE E++K
Sbjct: 13 KHYEFLYDSKIGSGAYANVYMGRDIYNDSSTVAIKIISNNLIKSDYTSQQIKREVEIMKS 72
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
H+NIVKLL + IV E C GG L L + L E L + + +
Sbjct: 73 FNHQNIVKLLDVFHSTNNI--YIVTEYCNGGDLKTYL----GSRTLSEERALQIFKQILN 126
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
G++ L N +VHRDLKP NI+ +DG +K+TDFG A+ +Q + SL GT Y+
Sbjct: 127 GLQELLRNGIVHRDLKPANILL---QDG--IFKITDFGFAKRVQVDSTMSSLVGTPLYMA 181
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P + +R + + + D+WS+G+ LY + P+
Sbjct: 182 PQILKR--------QPYTSKSDIWSLGLILYEMIYKTTPW 213
>UniRef50_A0C2X8 Cluster: Chromosome undetermined scaffold_145,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_145,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 482
Score = 95.9 bits (228), Expect = 2e-18
Identities = 61/209 (29%), Positives = 104/209 (49%), Gaps = 11/209 (5%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LG+G+ +V++ K++G+ A+K N ++ + + E +L + IV+
Sbjct: 19 LGEGSFSSVYKVQRKSDGQYYAMKKVNISQQSLKERENALNEIRILASLDSPYIVEFKDA 78
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+Q+GR ++ME +GG L IL + G+QE E +L +T G+K L DN ++H
Sbjct: 79 FIDQDGRILYVIMEFASGGDLNQILKQGKLQGGVQEGEIWNILTQITLGVKILHDNGILH 138
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLK N+ G YK+ D ++ + + GT Y P++++
Sbjct: 139 RDLKSANVFVSKTPQG-NIYKIGDLNISK-VTHGANAKTQTGTPYYAAPEIWK------- 189
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFR 225
G+ + D+WSIG +Y +AT Q PFR
Sbjct: 190 -GEQYSWPCDIWSIGCIIYELATFQPPFR 217
>UniRef50_A0C214 Cluster: Chromosome undetermined scaffold_143,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_143,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 563
Score = 95.9 bits (228), Expect = 2e-18
Identities = 66/210 (31%), Positives = 107/210 (50%), Gaps = 19/210 (9%)
Query: 18 LGKGATGAVFQGVNKNNG-EPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKG G V++G K++ + VA+KT + + RE +L K+ H NIVKL+ +
Sbjct: 24 LGKGQFGTVYRGHYKDDQTKQVAIKTIPMHNSEQLQQHIKREIAILTKIDHPNIVKLIHV 83
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+ +++E C G L L+ ++ L E E ++ +H+ G + L ++H
Sbjct: 84 TKTSSNL--YMILEFCKDGDLAEYLNKKQDKR-LSELEAVIFFKHVIKGFQILHQEKVIH 140
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEE--EQFVSLYGTEEYLHPDMYERAVLR 194
RD+KP NI+ +N DG K+ DFG AR ++ E + +S G+ Y+ P + E
Sbjct: 141 RDIKPSNIL--LN-DGVA--KIADFGFARIIESEIDKMNLSRVGSPIYMAPQILE----- 190
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
G F + D+WSIGV Y + G P+
Sbjct: 191 ---GTYFTSKCDIWSIGVMFYELLYGVTPW 217
>UniRef50_A0BIC2 Cluster: Chromosome undetermined scaffold_11, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_11,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 518
Score = 95.9 bits (228), Expect = 2e-18
Identities = 64/222 (28%), Positives = 112/222 (50%), Gaps = 24/222 (10%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ---MREFEVLKKV 65
NY ++ LG+GA G V+QG++ VA+K + + R + ++ ++E E+LKK
Sbjct: 11 NYSYNLKHCLGEGAYGKVYQGLDTTTNLKVAIKKLDLRNFERDNYLKQSIIQEIEILKKF 70
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
H+NIVK + + Q R I+ E C G L I+ + E + +++ + G
Sbjct: 71 NHKNIVKFIDLISTQ--RSLYIITEFCKDGDLREIMSRKK----YNEQDAWKIMKQIIQG 124
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQE--EEQFVSLYGTEEYL 183
+ L N ++HRDLKP NI+ + +G +K+ DFG A+ + + S G+ Y+
Sbjct: 125 FRELVSNAIIHRDLKPANILSH---EG--VFKIADFGFAKYVDNFTNQLLRSCVGSPLYM 179
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
P + + RKP + D+WS+GV Y + +P++
Sbjct: 180 APQI----LARKP----YSTKCDIWSLGVIFYEMVFTDVPWK 213
>UniRef50_A6R025 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 821
Score = 95.9 bits (228), Expect = 2e-18
Identities = 60/174 (34%), Positives = 92/174 (52%), Gaps = 10/174 (5%)
Query: 53 DVQMREFEVLKKVKHENIVKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQ 111
++ RE ++LK + H NIVKL E+ G V I EL T G LF+ L+ + + L
Sbjct: 172 EIYQREVDILKDLDHPNIVKL---EQVIMGEKTVYIFQELVTAGDLFSFLEYKK--FNLS 226
Query: 112 EYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEE- 170
+ E +++ + + +L N+VHRD+KP N++ DG LTDFG AR L++E
Sbjct: 227 DSEAAVIVRQVAVAISYLHGKNIVHRDIKPDNVLMTSLSDGARVV-LTDFGCARRLEKES 285
Query: 171 EQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + GT EY P++ + K GK + VD+WS+G + TG PF
Sbjct: 286 SRMKTSIGTLEYTAPEVPQSEPPCK--GKGYTKAVDMWSLGCLTVVLLTGGSPF 337
>UniRef50_P57058 Cluster: Hormonally up-regulated neu
tumor-associated kinase; n=26; Eumetazoa|Rep: Hormonally
up-regulated neu tumor-associated kinase - Homo sapiens
(Human)
Length = 714
Score = 95.9 bits (228), Expect = 2e-18
Identities = 69/213 (32%), Positives = 111/213 (52%), Gaps = 23/213 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM---REFEVLKKVKHENIVKLL 74
LG+G+ V +G++ GE VA+K ++ + V RE ++ + ++H NI +LL
Sbjct: 68 LGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLL 127
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
I E + +VMELC GG+L + + + + L+E E + L + ++HL +
Sbjct: 128 DILETENSY--YLVMELCPGGNLMHKIYEKKR---LEESEARRYIRQLISAVEHLHRAGV 182
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFG---AARELQEEEQFVSLYGTEEYLHPDMYERA 191
VHRDLK N++ ++ED KL DFG A L + F + G+ Y P++ R
Sbjct: 183 VHRDLKIENLL--LDEDNNI--KLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLAR- 237
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K +G +D+WSIGV +Y + TG LPF
Sbjct: 238 -------KKYGPKIDVWSIGVNMYAMLTGTLPF 263
>UniRef50_UPI00015562C7 Cluster: PREDICTED: similar to MLCK protein,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to MLCK protein, partial - Ornithorhynchus
anatinus
Length = 729
Score = 95.5 bits (227), Expect = 3e-18
Identities = 66/223 (29%), Positives = 111/223 (49%), Gaps = 18/223 (8%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLG G G V + + K++G +A K + +V+ E ++ ++ H N+++L
Sbjct: 430 VLGGGRFGQVHKCMEKSSGLTLAAKIIKVKTAKDREEVK-NEINIMNQLSHVNLIQLYDA 488
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E + +VME GG LF+ + D + Y L E + +L + G+ +L + ++H
Sbjct: 489 FESKNNF--TLVMEYVDGGELFDRITDEK--YHLTELDVILFTRQICEGIHYLHQHYILH 544
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
DLKP NI+ +N+ G K+ DFG AR + E+ +GT E+L P++ + P
Sbjct: 545 LDLKPENIL-CVNQTG-NQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFP 602
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
D+WS+GV Y + +G PF G + ETM +I
Sbjct: 603 --------TDMWSVGVITYMLLSGLSPFL---GETDAETMNFI 634
>UniRef50_UPI0000F1F5BA Cluster: PREDICTED: similar to novel kinase
domain containing protein; n=2; Danio rerio|Rep:
PREDICTED: similar to novel kinase domain containing
protein - Danio rerio
Length = 704
Score = 95.5 bits (227), Expect = 3e-18
Identities = 64/215 (29%), Positives = 109/215 (50%), Gaps = 15/215 (6%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHEN 69
Y + VLG G G V + + ++G +A K S + +V E +V+ ++ H N
Sbjct: 418 YTINQQEVLGGGRYGQVHKCIENSSGLTLAAKIIKAKSQ-KEKEVVKNEIQVMNQLDHAN 476
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
+++L A E + ++V+E GG LF+ + D EN Y L E + ++ + + G++++
Sbjct: 477 LIQLYAAYESRNDI--ILVLEYVDGGELFDRIID-EN-YKLTELDTVMFIRQICEGLRYM 532
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189
++H DLKP NI+ T K+ DFG AR+ Q E+ +GT E+L P++
Sbjct: 533 HKMYILHLDLKPENILCVSRV--TNKVKIIDFGLARKYQPREKLRVNFGTPEFLSPEVVN 590
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ SF D+WS+GV Y + +G PF
Sbjct: 591 YDFV------SF--NTDMWSLGVITYMLLSGLSPF 617
>UniRef50_UPI00006CBF34 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 902
Score = 95.5 bits (227), Expect = 3e-18
Identities = 65/214 (30%), Positives = 110/214 (51%), Gaps = 20/214 (9%)
Query: 14 TTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKVKHENIV 71
T+ LG+G G V + GE VA+K + DV+ RE +LK ++H+NI+
Sbjct: 37 TSETLGEGTFGKVKVATHILTGEKVAIKILEKEKIQDVSDVERVSREIHILKLLRHQNII 96
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
+L I E + + ++ E +GG LF+ + +NT +QE E + + + +G++++
Sbjct: 97 QLYEIIETE--KQLFLITEYASGGELFDYI--VKNTK-VQEREASVFFQQIISGVEYIHK 151
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERA 191
+VHRD+KP N++ N+ K+ DFG + ++ E + G+ Y P+M
Sbjct: 152 LKIVHRDMKPENLLLSYNK----RIKIVDFGLSNTYKKNELLKTACGSPCYAAPEMI--- 204
Query: 192 VLRKPVGKSF-GATVDLWSIGVTLYHVATGQLPF 224
GK + G VD+WS GV L+ + G LPF
Sbjct: 205 -----AGKRYLGLGVDIWSCGVILFALVCGYLPF 233
>UniRef50_Q3V454 Cluster: 10 days embryo whole body cDNA, RIKEN
full-length enriched library, clone:2610009E10
product:inhibitor of kappaB kinase beta, full insert
sequence; n=3; Euteleostomi|Rep: 10 days embryo whole
body cDNA, RIKEN full-length enriched library,
clone:2610009E10 product:inhibitor of kappaB kinase
beta, full insert sequence - Mus musculus (Mouse)
Length = 225
Score = 95.5 bits (227), Expect = 3e-18
Identities = 54/176 (30%), Positives = 86/176 (48%), Gaps = 5/176 (2%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG G G V + N+ GE +A+K Q D E ++++++ H N+V
Sbjct: 15 WEMKERLGTGGFGNVIRWHNQATGEQIAIKQCRQELSPENRDRWCLEIQIMRRLNHPNVV 74
Query: 72 KLLAIEEEQEGRGK----VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
+ E + ++ ME C GG L L+ EN GL+E L +L + + ++
Sbjct: 75 AARDVPEGMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAVLTLLSDIASALR 134
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
+L +N ++HRDLKP NI+ E +K+ D G A+EL + S GT +YL
Sbjct: 135 YLHENRIIHRDLKPENIVLQQGEK-RLIHKIIDLGYAKELDQGSLCTSFVGTLQYL 189
>UniRef50_A2ACR7 Cluster: Cyclin-dependent kinase-like 3; n=10;
Eumetazoa|Rep: Cyclin-dependent kinase-like 3 - Mus
musculus (Mouse)
Length = 353
Score = 95.5 bits (227), Expect = 3e-18
Identities = 65/219 (29%), Positives = 117/219 (53%), Gaps = 22/219 (10%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENI 70
++ T +G+G+ G V + +K+ G VA+K F + + + RE + LK+ +HEN+
Sbjct: 3 MYETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKIATREIKFLKQFRHENL 62
Query: 71 VKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPEN-TYGLQEYEFLLVLEHLTAGMKH 128
V L+ + +++ K+ +V E +LD+ ++ +GL+ L + +++
Sbjct: 63 VNLIEVFRQKK---KIHLVFEFID----HTVLDELQHYCHGLESKRLRKYLFQILRAIEY 115
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEE-EQFVSLYGTEEYLHPDM 187
L +NN++HRD+KP NI+ +++ G T KL DFG AR L + + T Y P++
Sbjct: 116 LHNNNIIHRDIKPENIL--VSQSGIT--KLCDFGFARTLAAPGDVYTDYVATRWYRAPEL 171
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRP 226
VL+ S+G VD+W++G + +ATG PF P
Sbjct: 172 ----VLK---DTSYGKPVDIWALGCMIIEMATGH-PFLP 202
>UniRef50_A3IW14 Cluster: Serine/threonine protein kinase; n=2;
Chroococcales|Rep: Serine/threonine protein kinase -
Cyanothece sp. CCY 0110
Length = 594
Score = 95.5 bits (227), Expect = 3e-18
Identities = 68/213 (31%), Positives = 113/213 (53%), Gaps = 27/213 (12%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G+G G V+ +++ GE VA+K+ L+ P + +REF L ++H NIV AIE
Sbjct: 17 IGQGQFGQVYFAISRKTGEFVALKS---LAKGFPTNRFLREFSCLVSLRHPNIVACEAIE 73
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT---AGMKHLRDNNL 134
G+G+ +VME C GG+L N+++ E +L L+ +T AG++ N+
Sbjct: 74 --YHGKGRYLVMEYCEGGTLRNLMNVS------AELSLILCLDLITDILAGLEQAHQQNI 125
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQE--EEQFVSLY-GTEEYLHPDMYERA 191
+H D+KP NI+ + D K+TDFG A+ +Q+ + S Y G+ Y+ P+ +
Sbjct: 126 IHCDIKPENILLSLTAD-KWIGKVTDFGIAKTVQDSSNDNLESGYTGSPAYMAPERF--- 181
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
GK + D++S+G+ Y + GQ PF
Sbjct: 182 -----YGK-YSYACDIYSVGIIFYELMIGQRPF 208
>UniRef50_Q2QSC9 Cluster: Protein kinase domain containing protein,
expressed; n=3; Oryza sativa|Rep: Protein kinase domain
containing protein, expressed - Oryza sativa subsp.
japonica (Rice)
Length = 1346
Score = 95.5 bits (227), Expect = 3e-18
Identities = 71/213 (33%), Positives = 113/213 (53%), Gaps = 26/213 (12%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPH-DVQ--MREFEVLKKVKHENIVKL 73
++G+G+ G V+ G K + VA+K L H + D+ +E E+L+K+KHENI+++
Sbjct: 11 LVGEGSFGKVYMGRRKYTRQTVAMKFI--LKHGKTDKDIHNLRQEIEILRKLKHENIIEM 68
Query: 74 L-AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
+ + E QE +V E G LF +L+D + L E + + + L + +L N
Sbjct: 69 IDSFETPQEF---CVVTEFAQG-ELFEVLEDDKC---LPEEQVQAIAKQLVKALHYLHSN 121
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERA 191
++HRD+KP NI+ I + KL DFG AR + + S+ GT Y+ P++
Sbjct: 122 RIIHRDMKPQNIL--IGKGSVV--KLCDFGFARAMSANTVVLRSIKGTPLYMAPEL---- 173
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
V +P + T DLWS+GV LY + GQ PF
Sbjct: 174 VREQP----YNHTADLWSLGVILYELFVGQPPF 202
>UniRef50_Q8WQ18 Cluster: Protein kinase; n=1; Nyctotherus
ovalis|Rep: Protein kinase - Nyctotherus ovalis
Length = 465
Score = 95.5 bits (227), Expect = 3e-18
Identities = 78/232 (33%), Positives = 112/232 (48%), Gaps = 25/232 (10%)
Query: 3 FLRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVL 62
F S YV+ LG G G V G + VA+K + P + M E ++L
Sbjct: 31 FKENSHQYVYK--DFLGHGRFGRVLLGESPETHHQVAIKVLPKQD--LPVEKLMSEVDIL 86
Query: 63 KKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHL 122
V H NIVK + E + R IVME C GG LF + +N + E E +V+E +
Sbjct: 87 SAVDHPNIVKYMKHYESK--RYLYIVMEYCPGGDLFQKVIK-QNKFN--EAEAAIVMEEV 141
Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEY 182
+ H ++HRDLKP NIM + DG T K+ DFG + + + E L GT Y
Sbjct: 142 LRAINHCHHLGIIHRDLKPENIM--YSSDG--TLKIIDFGLSIK-ENTEPSEQLVGTAYY 196
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKE 234
+ P+ ++R+ + F D+WS+GV L+ + TG F P GGR +E
Sbjct: 197 MAPE-----IVRE---EKFTKAGDIWSLGVLLHILLTG---FVPLGGRTFEE 237
>UniRef50_Q55CA6 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 635
Score = 95.5 bits (227), Expect = 3e-18
Identities = 67/210 (31%), Positives = 110/210 (52%), Gaps = 21/210 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA VF+G+N +G+ VA+K F + H EF++L+++ HENIV++L
Sbjct: 83 IGKGAFATVFKGLNTLSGDFVAIKRFEKSKISNEQHSSVSTEFDILQRLNHENIVRILGR 142
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNLV 135
EE + I +E GSL IL N +G E +E++ G+ +L ++
Sbjct: 143 EENE--NYIYIFLEYMENGSLSTIL----NNFGTFPESLICNYVENVLKGLVYLHQEGVI 196
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYERAVLR 194
HRD+K NI+ IN+ G KL+DFG A E ++E ++ S+ GT ++ P++ E +
Sbjct: 197 HRDIKAANIL--INKAGEA--KLSDFGTAGEIIKESDKRYSVVGTPYWMAPEVIEIS--- 249
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
D+WS+G T+ + T P+
Sbjct: 250 -----GHCQVSDIWSLGCTIIELFTSYPPY 274
>UniRef50_Q4E2U7 Cluster: Protein kinase, putative; n=2; Trypanosoma
cruzi|Rep: Protein kinase, putative - Trypanosoma cruzi
Length = 1037
Score = 95.5 bits (227), Expect = 3e-18
Identities = 69/229 (30%), Positives = 111/229 (48%), Gaps = 21/229 (9%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFN--QLSHMRPHDVQMREFEVLKKVKHENIVKLL 74
++G G V+ G++ +G VA+K N +++ + +EF +LK ++H NIV
Sbjct: 307 LIGVGGFAKVYAGMDCVSGRLVAIKEINIAEINDQAALNAIGKEFGLLKSLRHPNIVSYQ 366
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNN 133
E + IVMEL TGGS +L+ YG L+E HL + +
Sbjct: 367 LFEHSASQKVCRIVMELLTGGSTLALLE----KYGPLREPILRKFARHLLEAIAFIHKEG 422
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVS-LYGTEEYLHPDMYERAV 192
+ HRD+KP NI+ +++ G KL DFG ++ + E + + + GT Y+ P+
Sbjct: 423 ISHRDIKPANIL--VSDRGVV--KLCDFGCSKRVNELSKSTNCVIGTPLYMSPEF----- 473
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
+ F D+WS+ +L+ + TG LP+ R N MFYITT
Sbjct: 474 ----IKGEFDPKSDIWSMACSLFELGTGLLPWHHAKVRDNLPLMFYITT 518
>UniRef50_A0D261 Cluster: Chromosome undetermined scaffold_35, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_35,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 545
Score = 95.5 bits (227), Expect = 3e-18
Identities = 69/227 (30%), Positives = 118/227 (51%), Gaps = 23/227 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ---MREFEVLKKVKHENIVKLL 74
LGKGA G V++G+N + + VA+K + S M+ D + + E ++LK +K+ NI+++
Sbjct: 28 LGKGAYGTVYKGMNIHTRQNVAIKLVRK-SDMKDVDDEKQLLNEIQILKSLKNPNIIEI- 85
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
I+ Q I++E C G L +++ ++FL ++ LTA L +
Sbjct: 86 -IDVLQTENNYYIILEYCNHGDLESLIYKTHQITHEDHFQFL--IDILTA-FTTLIKQGI 141
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV--SLYGTEEYLHPDMYERAV 192
+HRDLKP NI+ +I E+ +KL DFG AR++ + + S GT Y+ P +
Sbjct: 142 MHRDLKPANILVHI-ENNRKIFKLGDFGFARQISNYKNQIMESKVGTPYYMSPQILN--- 197
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
G+ + + D+WSIG+ LY + + P+ GR E ++ I
Sbjct: 198 -----GQQYTSKSDIWSIGLMLYQIIYQKTPWL---GRSESELLYNI 236
>UniRef50_A0BXW7 Cluster: Chromosome undetermined scaffold_135,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_135,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 410
Score = 95.5 bits (227), Expect = 3e-18
Identities = 69/231 (29%), Positives = 120/231 (51%), Gaps = 21/231 (9%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQ--LSHMRPHDVQMREFEVLKKVKHENIVKL 73
++LG G+ V G++KN+ E A+K + + L+ + + RE +LK+++H+NI+KL
Sbjct: 146 TILGSGSFAMVRLGIDKNSKEKYAIKIYEKIKLNDSQKMNNVKREISILKRIEHQNIIKL 205
Query: 74 L-AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
AIE+++ +VME + SL + + N L E E L + + +K+L D
Sbjct: 206 YWAIEDKKSIN---LVMEYISSQSLASYIKSKPNRI-LPEKECLSLFYQIAMAIKYLHDL 261
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAV 192
N+ HRD+K N++ T KL DFG A + ++ GT Y+ P++ + V
Sbjct: 262 NICHRDIKLDNVLMM----KTNVVKLIDFGFAICMPLNQKTNVFCGTPHYMSPEIIAK-V 316
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
P A+ D+WS+G+ L + TG+ PF+ G+ +K+ I +K
Sbjct: 317 PHHP------ASSDIWSLGILLSRMITGEYPFK---GQNDKDLYRQIQCQK 358
>UniRef50_Q6IWN3 Cluster: P21-activated kinase Cla4; n=1; Ustilago
maydis|Rep: P21-activated kinase Cla4 - Ustilago maydis
(Smut fungus)
Length = 827
Score = 95.5 bits (227), Expect = 3e-18
Identities = 63/217 (29%), Positives = 117/217 (53%), Gaps = 19/217 (8%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
N ++S +G+GA+G+VF G+ VA+KT + LS ++ + E V+K+ +H
Sbjct: 551 NMLYSKIKKVGQGASGSVFVAKTLATGQRVAIKTMD-LSQQPRKELIVNEILVMKESQHP 609
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
NIV L + VI ME GG+L +++D+ NT L+E + + G++H
Sbjct: 610 NIVNFLNSFLVRNNELWVI-MEYMEGGALTDVIDN--NT--LEEDQIAAICLETCKGLEH 664
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEE-QFVSLYGTEEYLHPDM 187
L +++HRD+K N++ +N G K+TDFG +L +++ + ++ GT ++ P++
Sbjct: 665 LHSQSIIHRDIKSDNVL--LNASGQV--KITDFGFCAKLTDQKSKRATMVGTPYWMAPEV 720
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ K +GA VD+WS+G+ + + P+
Sbjct: 721 VKQ--------KEYGAKVDIWSLGIMAIEMIENEPPY 749
>UniRef50_P11801 Cluster: Serine/threonine-protein kinase H1; n=30;
Eumetazoa|Rep: Serine/threonine-protein kinase H1 - Homo
sapiens (Human)
Length = 424
Score = 95.5 bits (227), Expect = 3e-18
Identities = 64/211 (30%), Positives = 116/211 (54%), Gaps = 17/211 (8%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
+++G+G+ V + ++ +P A+K + + +V E VL++V+H NI++L+
Sbjct: 102 ALIGRGSFSRVVRVEHRATRQPYAIKMI-ETKYREGREVCESELRVLRRVRHANIIQLVE 160
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E QE +VMEL TGG LF+ + + E + VL+ + G+++L +
Sbjct: 161 VFETQER--VYMVMELATGGELFDRIIAKGS---FTERDATRVLQMVLDGVRYLHALGIT 215
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFG--AARELQEEEQFVSLYGTEEYLHPDMYERAVL 193
HRDLKP N++ Y + + +TDFG +AR+ ++ + GT EY+ P++ ++
Sbjct: 216 HRDLKPENLL-YYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEV----LV 270
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
RKP S VD+W++GV Y + +G +PF
Sbjct: 271 RKPYTNS----VDMWALGVIAYILLSGTMPF 297
>UniRef50_UPI000150A956 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 471
Score = 95.1 bits (226), Expect = 4e-18
Identities = 60/219 (27%), Positives = 106/219 (48%), Gaps = 20/219 (9%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHEN 69
Y WS LG G G+V K + A+K + S +R + E ++K++ H N
Sbjct: 28 YEWSKKRTLGSGQFGSVVSCKLKGTNDTRAIKVIPK-SRVRDPQQFLNEINIMKELDHPN 86
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
+++L E+Q R + MELC+GG LF+++ + E E LV + + + +
Sbjct: 87 VIRLYETFEDQ--RNVYLSMELCSGGELFDVITAKKK---FSEEEARLVFNQIVSAVSYC 141
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAA----RELQEEEQFVSLYGTEEYLHP 185
NN+ HRDLKP N + + ++ K+ DFG + + Q+++ + G+ Y+ P
Sbjct: 142 HANNICHRDLKPENFL-LLQKESLDNIKVADFGLSCIFVDKQQKKQDILGKTGSSYYMAP 200
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ + + D+WS+GV LY + +G PF
Sbjct: 201 EVLQGI---------YNELCDVWSLGVILYILLSGIPPF 230
>UniRef50_A2BFU1 Cluster: Novel protein; n=6; Euteleostomi|Rep:
Novel protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 500
Score = 95.1 bits (226), Expect = 4e-18
Identities = 68/211 (32%), Positives = 112/211 (53%), Gaps = 22/211 (10%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM-REFEVLKKVKHENIVKLL- 74
V+G+G+ G V++G K +G+ VA+K ++ + RE ++++ +KH NIV LL
Sbjct: 9 VIGEGSFGRVYKGRRKFSGQVVALKFIPKVGRSEKDLRSLKREIDIMRGLKHPNIVLLLD 68
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E E+E V+V+ G LF IL+D + L E + + L + + +L + +
Sbjct: 69 SFETERE----VVVVTEYAEGELFQILEDDGS---LPEKQVREIACQLVSALYYLHSHRI 121
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAVL 193
+HRD+KP NI+ + + G KL DFG AR + + S+ GT Y+ P++ E
Sbjct: 122 LHRDMKPQNIL--LGKGGVV--KLCDFGFARAMSVSTLVLTSIKGTPLYMSPELVEE--- 174
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + + DLWS+G LY + TG PF
Sbjct: 175 -----KPYDHSTDLWSLGCILYELHTGAPPF 200
>UniRef50_Q9NH60 Cluster: Calcium/calmodulin-dependent protein
kinase II isoform B; n=3; Bilateria|Rep:
Calcium/calmodulin-dependent protein kinase II isoform B
- Caenorhabditis elegans
Length = 520
Score = 95.1 bits (226), Expect = 4e-18
Identities = 71/220 (32%), Positives = 103/220 (46%), Gaps = 19/220 (8%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKK 64
S+NY LGKGA V + V+K G A K N + D Q RE + +K
Sbjct: 9 SDNY--DVKEELGKGAFSVVRRCVHKTTGLEFAAKIINT-KKLSARDFQKLEREARICRK 65
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
++H NIV+L + QE +V +L TGG LF +D E + ++ +
Sbjct: 66 LQHPNIVRLH--DSIQEESFHYLVFDLVTGGELF---EDIVAREFYSEADASHCIQQILE 120
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
+ + N +VHRDLKP N++ G KL DFG A E+ + E + GT YL
Sbjct: 121 SIAYCHSNGIVHRDLKPENLLLASKAKGAAV-KLADFGLAIEVNDSEAWHGFAGTPGYLS 179
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ ++ KP VD+W+ GV LY + G PF
Sbjct: 180 PEVLKKDPYSKP--------VDIWACGVILYILLVGYPPF 211
>UniRef50_Q9NH59 Cluster: Calcium/calmodulin-dependent protein
kinase II isoform C; n=8; Eumetazoa|Rep:
Calcium/calmodulin-dependent protein kinase II isoform C
- Caenorhabditis elegans
Length = 533
Score = 95.1 bits (226), Expect = 4e-18
Identities = 71/220 (32%), Positives = 103/220 (46%), Gaps = 19/220 (8%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKK 64
S+NY LGKGA V + V+K G A K N + D Q RE + +K
Sbjct: 9 SDNY--DVKEELGKGAFSVVRRCVHKTTGLEFAAKIINT-KKLSARDFQKLEREARICRK 65
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
++H NIV+L + QE +V +L TGG LF +D E + ++ +
Sbjct: 66 LQHPNIVRLH--DSIQEESFHYLVFDLVTGGELF---EDIVAREFYSEADASHCIQQILE 120
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
+ + N +VHRDLKP N++ G KL DFG A E+ + E + GT YL
Sbjct: 121 SIAYCHSNGIVHRDLKPENLLLASKAKGAAV-KLADFGLAIEVNDSEAWHGFAGTPGYLS 179
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ ++ KP VD+W+ GV LY + G PF
Sbjct: 180 PEVLKKDPYSKP--------VDIWACGVILYILLVGYPPF 211
>UniRef50_Q9NH58 Cluster: Calcium/calmodulin-dependent protein
kinase II isoform D; n=2; Caenorhabditis elegans|Rep:
Calcium/calmodulin-dependent protein kinase II isoform D
- Caenorhabditis elegans
Length = 571
Score = 95.1 bits (226), Expect = 4e-18
Identities = 71/220 (32%), Positives = 103/220 (46%), Gaps = 19/220 (8%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKK 64
S+NY LGKGA V + V+K G A K N + D Q RE + +K
Sbjct: 9 SDNY--DVKEELGKGAFSVVRRCVHKTTGLEFAAKIINT-KKLSARDFQKLEREARICRK 65
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
++H NIV+L + QE +V +L TGG LF +D E + ++ +
Sbjct: 66 LQHPNIVRLH--DSIQEESFHYLVFDLVTGGELF---EDIVAREFYSEADASHCIQQILE 120
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
+ + N +VHRDLKP N++ G KL DFG A E+ + E + GT YL
Sbjct: 121 SIAYCHSNGIVHRDLKPENLLLASKAKGAAV-KLADFGLAIEVNDSEAWHGFAGTPGYLS 179
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ ++ KP VD+W+ GV LY + G PF
Sbjct: 180 PEVLKKDPYSKP--------VDIWACGVILYILLVGYPPF 211
>UniRef50_Q7QBH3 Cluster: ENSANGP00000014786; n=3; Culicidae|Rep:
ENSANGP00000014786 - Anopheles gambiae str. PEST
Length = 1136
Score = 95.1 bits (226), Expect = 4e-18
Identities = 62/209 (29%), Positives = 103/209 (49%), Gaps = 18/209 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDV--QMREFEVLKKVKHENIVKLLA 75
LG+G G V G+NK G+ VA+KT + D+ RE +++ V+H NI+ +
Sbjct: 33 LGQGTYGKVQLGINKETGQEVAIKTIKKSKIETEADLIRIRREVQIMSSVQHPNIIHIYE 92
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E +E V+VME GG L++ L + + L E E + ++ + + + +
Sbjct: 93 VFENRE--KMVLVMEFAAGGELYDYLSERK---VLAEEEARRIFRQVSTAIYYCHKHKIC 147
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLK NI+ ++E G K+ DFG + E+ + G+ Y P++ + +
Sbjct: 148 HRDLKLENIL--LDEHGNA--KIADFGLSNVFDEQRLLATFCGSPLYASPEIVKGTPYQ- 202
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
G VD WS+GV LY + G +PF
Sbjct: 203 ------GPEVDCWSLGVLLYTLVYGAMPF 225
>UniRef50_Q3LDS4 Cluster: Carbon catabolite derepressing protein
kinase; n=4; Eukaryota|Rep: Carbon catabolite
derepressing protein kinase - Nyctotherus ovalis
Length = 252
Score = 95.1 bits (226), Expect = 4e-18
Identities = 69/223 (30%), Positives = 111/223 (49%), Gaps = 21/223 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKVKHENIVKLLA 75
LG+G G V + GE VA+K + DV+ RE +LK ++H N+++L
Sbjct: 26 LGEGTFGKVRIATHILTGEKVAIKILEKDRVTDVSDVERVAREIHILKIIRHPNLIQLYE 85
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
I E + +V E TGG L+ + NT L+E E + + + +G++++ +V
Sbjct: 86 IVETT--KQLYLVTEYATGGELYEYI--VSNTR-LEESEACRLFQQIISGIEYIHKLRIV 140
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLKP N++ D + KL DFG + +++E+ + G+ Y P+M
Sbjct: 141 HRDLKPENLLL----DSSKNIKLGDFGLSNTYKQDEKLKTACGSPCYAAPEMI------- 189
Query: 196 PVGKSF-GATVDLWSIGVTLYHVATGQLPFR-PYGGRRNKETM 236
GK + G VD+WS GV L+ + G LPF P G K+ +
Sbjct: 190 -AGKKYNGLQVDIWSAGVVLFALLCGHLPFEDPNTGNLYKKIL 231
>UniRef50_Q229R8 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1237
Score = 95.1 bits (226), Expect = 4e-18
Identities = 74/209 (35%), Positives = 109/209 (52%), Gaps = 38/209 (18%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLL-AI 76
+G+G+ G VF+G KN G+ +A+K ++ +++KHENI+ LL A
Sbjct: 10 IGEGSFGKVFKGRRKNTGQILALKFISK-----------------RRLKHENIILLLDAF 52
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E E +V E G LF IL+D + L E E + + L + +L N ++H
Sbjct: 53 ETPHEF---CVVTEFAQG-ELFEILEDDRS---LPESEVRKIAQQLILALDYLHSNRIIH 105
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAVLRK 195
RD+KP NI+ I+ +G KL DFG AR L Q + S+ GT Y+ P++ V +
Sbjct: 106 RDMKPQNIL--ISANGVV--KLCDFGFARALSSNTQVLTSIKGTPLYMAPEL----VKEQ 157
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P + TVDLWS+GV LY + GQ PF
Sbjct: 158 P----YNHTVDLWSLGVILYELFVGQPPF 182
>UniRef50_A2FCZ8 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 966
Score = 95.1 bits (226), Expect = 4e-18
Identities = 64/209 (30%), Positives = 104/209 (49%), Gaps = 20/209 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLAI 76
+G+G+ G V++ K G VA+K ++L + +R E +L+KV H NI++LL +
Sbjct: 10 IGEGSFGRVYKARRKYTGRLVAIKMIHKLGQSQDSLASLRREINILQKVDHPNIMRLLEV 69
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E +V EL G LF ++ D + L E V L + + +L ++H
Sbjct: 70 FETNTD--VCLVTELGRG-DLFQVIQDQQT---LPESVLKSVAAQLVSALLYLHQQRIIH 123
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAVLRK 195
RD+KP N++ +N T KL DFG AR L + S+ GT Y+ P++ +
Sbjct: 124 RDIKPQNVLISLN----NTVKLCDFGFARALSNTTLVLNSIKGTPLYMAPELVQE----- 174
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + VD+WS+G LY + G+ PF
Sbjct: 175 ---QQYNEKVDIWSLGAILYELYYGKTPF 200
>UniRef50_A2DH03 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 376
Score = 95.1 bits (226), Expect = 4e-18
Identities = 62/210 (29%), Positives = 103/210 (49%), Gaps = 15/210 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTF--NQLSHMRPHDVQM-REFEVLKKVKHENIVKLL 74
+G GA V+ +++N E A+K F ++L H+ Q+ RE ++++ H NI+KL
Sbjct: 39 IGNGAFSNVYLAIDQNTKEKYAIKKFKLSELQHIENGVSQLEREISLMRRYSHNNILKLF 98
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E +V+E GSLF++++ P LQ+ + + +++L +N +
Sbjct: 99 EVLHNTEKDIVYLVIEYANCGSLFDLINQP---IPLQDNYVCSIFHQILEALQYLHNNGM 155
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
VH+D+KP NI+ I DG L DFG Q E V G+ Y P+
Sbjct: 156 VHQDIKPSNIL--IKSDGRAI--LADFGVGHSFQSTEMVV---GSPAYQAPEALTDGDC- 207
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ S A D+WS+GVTL+ Q+P+
Sbjct: 208 -GIQSSSPAKEDVWSLGVTLFQTEYQQIPY 236
>UniRef50_A0CYL8 Cluster: Chromosome undetermined scaffold_31, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_31,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 333
Score = 95.1 bits (226), Expect = 4e-18
Identities = 71/200 (35%), Positives = 102/200 (51%), Gaps = 26/200 (13%)
Query: 38 VAVKTFNQ-LSHMRPHDVQMREFEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGS 96
VA+K +N L + +E E+LKK+ HENIVK L + IV+E G +
Sbjct: 125 VAIKKYNSNLLKSEQKKLLSKETEILKKLDHENIVKFLGTYKN------TIVLEFIDGHT 178
Query: 97 LFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTY 156
L N L + N LQE E + + G+K+L N+ HRDLK NIM IN+
Sbjct: 179 LTNYLKNQPNRR-LQEKEAKQIYSQIRDGIKYLHSKNIFHRDLKADNIM-IINQQ----V 232
Query: 157 KLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYH 216
KL DFG A E Q F GT Y+ P++++ +KP G D+W++GV LY
Sbjct: 233 KLIDFGLASENQLCSDFC---GTPAYMAPEIFQ----KKPYD---GRKADIWALGVLLYQ 282
Query: 217 VATGQLPFRPYGGRRNKETM 236
+ G++PF G+ ++E M
Sbjct: 283 ILCGKVPF---PGKNDEEIM 299
>UniRef50_A0CJD7 Cluster: Chromosome undetermined scaffold_2, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_2,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 492
Score = 95.1 bits (226), Expect = 4e-18
Identities = 62/216 (28%), Positives = 113/216 (52%), Gaps = 22/216 (10%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
+Y++S +++GKG+ G V+ G ++ + VA+K ++ + D+Q +E ++K++ H
Sbjct: 18 SYIFSLKAIIGKGSYGTVYLGKHETTQKLVAIKVIDRRNV--DFDIQSQEISIMKQLNHP 75
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
NIV+L I+ I+ E C G L L+ L E L +++ + G+K
Sbjct: 76 NIVQL--IDFVISVNNLYIITEYCNGTDLKTYLNQHNP---LSEESALKLIKSIIKGLKC 130
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMY 188
+ NN +HRD+KP NI+ + N+ K+ DFG +R + S+ GT Y+ P
Sbjct: 131 IIQNNFIHRDIKPANIL-FDNDQ----LKIADFGFSRRI--NNTMTSIVGTPMYMAPQ-- 181
Query: 189 ERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+L K + + + D+WS+GV + + G+LP+
Sbjct: 182 ---ILFK---QEYTSKCDIWSLGVVFFELLFGKLPW 211
>UniRef50_A0BG89 Cluster: Chromosome undetermined scaffold_105,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_105,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 409
Score = 95.1 bits (226), Expect = 4e-18
Identities = 71/225 (31%), Positives = 110/225 (48%), Gaps = 19/225 (8%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
+ S +GKG G V +K G VAVK + + RE ++LK+++H NIV
Sbjct: 91 YEIVSEIGKGGQGTVLLARHKFIGSFVAVKITRDIEE--EDSIIKRESKILKELQHRNIV 148
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
K+ + + +I+ME GGSL ++ N + E E + ++ + +
Sbjct: 149 KVFQTLYFSKTKECIIIMEYLDGGSLLQLI---RNKGTVSEQEAKIYIKQIVEALLFCHS 205
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAA--RELQEEEQFVSLYGTEEYLHPDMYE 189
VHRDLK NIM +N+ G T KL DFG A Q E + +++ GT Y+ P++
Sbjct: 206 KTFVHRDLKLENIM-LVNQ-GNTWVKLIDFGLAGVAGTQRETETMNV-GTLPYMPPEVLN 262
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKE 234
+ K VD+W IGV +Y + G+LPF+ GR N+E
Sbjct: 263 GKL------KFVSPCVDVWGIGVIMYSLLYGKLPFK---GRTNEE 298
>UniRef50_Q0VD65 Cluster: MYO3A protein; n=22; Euteleostomi|Rep:
MYO3A protein - Homo sapiens (Human)
Length = 664
Score = 95.1 bits (226), Expect = 4e-18
Identities = 62/218 (28%), Positives = 110/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ E+ +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AEYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>UniRef50_A3LSM4 Cluster: Predicted protein; n=1; Pichia stipitis|Rep:
Predicted protein - Pichia stipitis (Yeast)
Length = 1462
Score = 95.1 bits (226), Expect = 4e-18
Identities = 63/227 (27%), Positives = 118/227 (51%), Gaps = 22/227 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVK------TFNQLSHMRPHDVQMREFEV 61
E + W ++G+G+ GAV+ G+N GE +AVK + S + +E E
Sbjct: 1159 EEFAWIKGELIGRGSFGAVYLGLNVTTGEMLAVKQVVVSPEYRDSSKSGGIEALHKEVET 1218
Query: 62 LKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLE 120
+K + H NIV+ L EQ+G + +E TGGS+ + + ++G +E + +
Sbjct: 1219 MKDLDHVNIVQYLGY--EQKGHIYSLFLEYVTGGSIASCM----KSFGKFEEPLIRFISK 1272
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAR---ELQEEEQFVSLY 177
+ G+++L N ++HRDLK N++ + DGT K++DFG ++ ++ +S+
Sbjct: 1273 QVLLGLEYLHSNGILHRDLKADNLL--LELDGTC--KISDFGISKRSTDIYANNAEMSMQ 1328
Query: 178 GTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
GT ++ P++ + V K G + A +D+WS+G + + G+ P+
Sbjct: 1329 GTVFWMAPEVIDSIVEDKKQG--YSAKIDIWSLGCVVLEMFAGKRPW 1373
>UniRef50_Q8NEV4 Cluster: Myosin IIIA; n=68; Coelomata|Rep: Myosin
IIIA - Homo sapiens (Human)
Length = 1616
Score = 95.1 bits (226), Expect = 4e-18
Identities = 62/218 (28%), Positives = 110/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ E+ +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AEYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>UniRef50_P11730 Cluster: Calcium/calmodulin-dependent protein
kinase type II gamma chain; n=38; Coelomata|Rep:
Calcium/calmodulin-dependent protein kinase type II
gamma chain - Rattus norvegicus (Rat)
Length = 527
Score = 95.1 bits (226), Expect = 4e-18
Identities = 74/209 (35%), Positives = 101/209 (48%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V K + + A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + + + + H+ +++VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDIWACGVILYILLVGYPPF 214
>UniRef50_Q13555 Cluster: Calcium/calmodulin-dependent protein
kinase type II gamma chain; n=237; Eumetazoa|Rep:
Calcium/calmodulin-dependent protein kinase type II
gamma chain - Homo sapiens (Human)
Length = 558
Score = 95.1 bits (226), Expect = 4e-18
Identities = 74/209 (35%), Positives = 101/209 (48%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V K + + A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + + + + H+ +++VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDIWACGVILYILLVGYPPF 214
>UniRef50_UPI0000D56DEC Cluster: PREDICTED: similar to CG10967-PA;
n=3; Endopterygota|Rep: PREDICTED: similar to CG10967-PA
- Tribolium castaneum
Length = 779
Score = 94.7 bits (225), Expect = 6e-18
Identities = 70/225 (31%), Positives = 109/225 (48%), Gaps = 22/225 (9%)
Query: 9 NYVWSTTSVLGKGATGAVFQG-VNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK- 66
+Y ++T ++G GA VF+G KN VA+K + ++ + +E ++L+++
Sbjct: 6 DYEYNTKDIIGHGAFAVVFKGRERKNPSNTVAIKCITK-KNIAKQSLLGKEIKILQELTE 64
Query: 67 --HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
HEN+V L +E +VME C GG L + L + T L E L L L
Sbjct: 65 LHHENVVALFDCKESPNN--VYLVMEYCKGGDLADYLA-AKGT--LSEDTIRLFLIQLAG 119
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYIN----EDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
MK L +VHRDLKP NI+ + + K+ DFG AR LQE +L G+
Sbjct: 120 AMKALSAKGIVHRDLKPQNILITYDVPNPQPSQIKLKIADFGFARFLQEGVMAATLCGSP 179
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
Y+ P++ + + A DLWS+G ++ TG+ PF+
Sbjct: 180 MYMAPEVI--------LALQYDAKADLWSLGTIVFQCLTGKAPFQ 216
>UniRef50_UPI000069FC64 Cluster: Serine/threonine-protein kinase
Nek5 (EC 2.7.11.1) (NimA-related protein kinase 5).;
n=1; Xenopus tropicalis|Rep: Serine/threonine-protein
kinase Nek5 (EC 2.7.11.1) (NimA-related protein kinase
5). - Xenopus tropicalis
Length = 672
Score = 94.7 bits (225), Expect = 6e-18
Identities = 67/212 (31%), Positives = 105/212 (49%), Gaps = 20/212 (9%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHM--RPHDVQMREFEVLKKVKHENIVKLL 74
++G+GA G + K++ +K N LS M + + +E +L K+KH NIV
Sbjct: 9 MIGEGAFGKAYLAKGKSDNMQCVIKEIN-LSKMPTKEKEASHKEVVLLAKMKHPNIVTFF 67
Query: 75 AIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
+ EE R K+ IVME C GG L ++ +E + L ++ G+KH+ D
Sbjct: 68 SSIEE---RNKLYIVMEYCDGGDLMKRVNKQRGVL-FEEDQILSWFVQISLGLKHIHDRK 123
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAV 192
++HRD+K NI +++ +GT KL DFG AR L + + GT YL P++ E
Sbjct: 124 VLHRDIKAQNI--FLSNNGTLA-KLGDFGIARMLNNTMELARTCVGTPYYLSPEICE--- 177
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + D+WS+G LY + + PF
Sbjct: 178 -----NKPYNNKTDIWSLGCVLYELCALKHPF 204
>UniRef50_UPI000069FC63 Cluster: Serine/threonine-protein kinase
Nek5 (EC 2.7.11.1) (NimA-related protein kinase 5).;
n=1; Xenopus tropicalis|Rep: Serine/threonine-protein
kinase Nek5 (EC 2.7.11.1) (NimA-related protein kinase
5). - Xenopus tropicalis
Length = 624
Score = 94.7 bits (225), Expect = 6e-18
Identities = 67/212 (31%), Positives = 105/212 (49%), Gaps = 20/212 (9%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHM--RPHDVQMREFEVLKKVKHENIVKLL 74
++G+GA G + K++ +K N LS M + + +E +L K+KH NIV
Sbjct: 9 MIGEGAFGKAYLAKGKSDNMQCVIKEIN-LSKMPTKEKEASHKEVVLLAKMKHPNIVTFF 67
Query: 75 AIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
+ EE R K+ IVME C GG L ++ +E + L ++ G+KH+ D
Sbjct: 68 SSIEE---RNKLYIVMEYCDGGDLMKRVNKQRGVL-FEEDQILSWFVQISLGLKHIHDRK 123
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAV 192
++HRD+K NI +++ +GT KL DFG AR L + + GT YL P++ E
Sbjct: 124 VLHRDIKAQNI--FLSNNGTLA-KLGDFGIARMLNNTMELARTCVGTPYYLSPEICE--- 177
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + D+WS+G LY + + PF
Sbjct: 178 -----NKPYNNKTDIWSLGCVLYELCALKHPF 204
>UniRef50_Q9QYZ3 Cluster: Putative uncharacterized protein Smok;
n=12; Murinae|Rep: Putative uncharacterized protein Smok
- Mus musculus (Mouse)
Length = 484
Score = 94.7 bits (225), Expect = 6e-18
Identities = 68/208 (32%), Positives = 108/208 (51%), Gaps = 20/208 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V ++ G VAVK + S + V M E E+L H NI+ LL +
Sbjct: 14 IGHGGCSKVMLARHRLTGSHVAVKMIRK-SECWCNPV-MSEVELLMMADHPNIISLLQVI 71
Query: 78 EEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E ++ KV ++MELC G SL+ + N LQE E + + L + M + + +VH
Sbjct: 72 ETKK---KVYLIMELCEGKSLYQHI---RNAGYLQEDEARALFKQLLSAMNYCHNQGIVH 125
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP NIM + +DG K+ DFG +++ ++ GT + P++ +L +P
Sbjct: 126 RDLKPDNIM--VEKDGKV--KIIDFGLGTQVKPGQKLNLFCGTYPFSAPEV----LLSRP 177
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
G +D+W++GV LY + TG++PF
Sbjct: 178 YD---GPKIDVWTLGVVLYFMVTGKVPF 202
>UniRef50_Q8IGZ0 Cluster: RE01659p; n=9; Endopterygota|Rep: RE01659p
- Drosophila melanogaster (Fruit fly)
Length = 569
Score = 94.7 bits (225), Expect = 6e-18
Identities = 61/212 (28%), Positives = 104/212 (49%), Gaps = 17/212 (8%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
+ TT +GKGA+G VF + N VAVKT + + + D+ + E VLK H+N+V
Sbjct: 293 YKTTQEVGKGASGIVFIAADLQNESQVAVKTID-MKNQSSKDLILTEIRVLKDFNHKNLV 351
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
L + +VME GG L +++ + ++E + V + L
Sbjct: 352 NFLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETV----MKERQIACVCRETLYAISFLHA 407
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERA 191
++HRD+K N++ + DG+ K+TDFG ++ +E+ ++ GT ++ P++ R
Sbjct: 408 KGIIHRDIKSDNVL--LGMDGSV--KVTDFGFCANIEGDEKRQTMVGTPYWMAPEVVTR- 462
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
K +G VD+WSIG+ + GQ P
Sbjct: 463 -------KKYGKKVDIWSIGIMAIEMIEGQPP 487
>UniRef50_A7S4Z6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 266
Score = 94.7 bits (225), Expect = 6e-18
Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 19/220 (8%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK 66
S NY ++G+G+ VF+ + + G A K +L+ + + +E V K ++
Sbjct: 2 SPNY--DMLELIGEGSFAKVFRCIERKTGLEFAAKEL-RLTDVEDKEKIEQEIAVWKDLR 58
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
HENIV L + +EG ++ME GGSLF+ + + TY E + LV L +
Sbjct: 59 HENIVSLYS--SIREGETVCLIMEYVAGGSLFD--EVIQQTY-YSEKQARLVTRQLLNAL 113
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVS--LYGTEEYLH 184
++L +VHRD+KP N++ T KL DFG A+ L + +S G +L
Sbjct: 114 EYLHSRRIVHRDIKPDNLL-LKRTGNNVTIKLADFGLAQALPNDTDVISCGASGAPMFLA 172
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P+ VL +P+G++ VD+W+ GV Y + G PF
Sbjct: 173 PE----TVLEEPIGRA----VDIWACGVIFYLLLVGYPPF 204
>UniRef50_A0DGC5 Cluster: Chromosome undetermined scaffold_5, whole
genome shotgun sequence; n=13; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_5, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 582
Score = 94.7 bits (225), Expect = 6e-18
Identities = 64/220 (29%), Positives = 108/220 (49%), Gaps = 16/220 (7%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM-REFEVLKK 64
GS ++ VLG+GA G V++ +K G A+K + S ++ + ++ E +LK
Sbjct: 138 GSIGSHYNFGKVLGQGAFGKVWKVTHKTTGLIRAIKQIKKSSIIKEEEQRLFSEMNILKN 197
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
+ H +IVKL + +++ +V E +GG LF D + E + +
Sbjct: 198 LDHPHIVKLFELYQDENNY--YLVTEYLSGGELF---DRIKKMSSFSESIAADYIRQILL 252
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
+ + N+VHRDLKP NI+ +I+ED + K+ DFG +R+ ++ GT Y+
Sbjct: 253 ATLYCHEQNIVHRDLKPENII-FISEDPQSQLKVIDFGTSRKFDNQKAMSKRLGTPYYIA 311
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ +G S+ D+WS GV LY + G PF
Sbjct: 312 PEV---------LGHSYTEKCDIWSCGVILYILLCGYPPF 342
>UniRef50_A0CPJ3 Cluster: Chromosome undetermined scaffold_23, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_23,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 482
Score = 94.7 bits (225), Expect = 6e-18
Identities = 62/208 (29%), Positives = 107/208 (51%), Gaps = 17/208 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM-REFEVLKKVKHENIVKLLAI 76
LG+GA G V++ V+ +G+ A+K N+L Q+ E +LK + H NI+K+
Sbjct: 45 LGQGAFGTVWKAVHIASGQLRAIKQINKLKANEDEYQQIINEVNILKSLDHPNIIKIFDY 104
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
EE + IV ELCTGG LF+ + ++ Y E E L ++ + + + + + +VH
Sbjct: 105 FEENDHL--YIVTELCTGGELFDKII--QSNY-FSEKEAALAMKQILSALNYCHQSKIVH 159
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RD+KP N++ Y +E + K+ DFG + + ++ GT Y+ P++
Sbjct: 160 RDIKPENLL-YDHEGEDSQLKIIDFGTSLK-YGNQKLEEKIGTVYYMAPEL--------- 208
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + + D+WS GV L+ + G PF
Sbjct: 209 IDEKYDEKCDIWSAGVVLFILLCGSPPF 236
>UniRef50_Q4X028 Cluster: Protein kinase, putative; n=6;
Trichocomaceae|Rep: Protein kinase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 1028
Score = 94.7 bits (225), Expect = 6e-18
Identities = 72/273 (26%), Positives = 123/273 (45%), Gaps = 26/273 (9%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR---EFEVLKKVKH 67
+++ T +GKGA V++ K +G A K ++ M+ + + E +++K +KH
Sbjct: 238 MYNVTGQIGKGAFATVYKLATKQHGAVYAAKELDKRRFMKNGILDQKVDNEMKIMKDLKH 297
Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVL-EHLTAGM 126
NIV+ I+ + R I+ME GG L L + +G + + L L +
Sbjct: 298 PNIVQY--IDHHEHDRWIYIIMEYVPGGELSTYL----SIHGKIPEDMVKTLARQLLHAL 351
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPD 186
++L + HRD+KP NI+ I KL+DFG ++ QEE + GT Y P+
Sbjct: 352 QYLHKRRITHRDIKPDNIL--IASLEPLRVKLSDFGLSKVAQEETFLKTFCGTLLYCAPE 409
Query: 187 MY------ERAVLRK--------PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRN 232
+Y R +RK P + +VD+WS G L+H+ +G P+ G R
Sbjct: 410 VYPEYENYRRGEIRKRRRLGDPPPKTSPYDQSVDMWSFGAVLFHILSGTPPYTGRGDDRG 469
Query: 233 KETMFYITTKKASGVISGTQTTENGPIDWAREL 265
+ + I T + + + +D+ R L
Sbjct: 470 SQMLRNIMTTEPDYDVLRREGVSEAGVDFVRRL 502
>UniRef50_Q3UIZ8 Cluster: Putative myosin light chain kinase 3; n=4;
Murinae|Rep: Putative myosin light chain kinase 3 - Mus
musculus (Mouse)
Length = 795
Score = 94.7 bits (225), Expect = 6e-18
Identities = 65/233 (27%), Positives = 114/233 (48%), Gaps = 18/233 (7%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK 66
S Y S VLG G G V + ++ G +A K ++ +++ + E ++ ++
Sbjct: 486 SAGYTVSQHEVLGGGRFGQVHRCTERSTGLALAAKII-KVKNVKDREDVKNEVNIMNQLS 544
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
H N+++L E + ++ME GG LF+ + D + Y L E + +L + G+
Sbjct: 545 HVNLIQLYDAFESKSSF--TLIMEYVDGGELFDRITDEK--YHLTELDVVLFTRQICEGV 600
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPD 186
+L + ++H DLKP NI+ +++ G K+ DFG AR + E+ +GT E+L P+
Sbjct: 601 HYLHQHYILHLDLKPENIL-CVSQTG-HQIKIIDFGLARRYKPREKLKVNFGTPEFLAPE 658
Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
+ + P D+WS+GV Y + +G PF G + ETM +I
Sbjct: 659 VVNYEFVSFP--------TDMWSVGVITYMLLSGLSPFL---GETDAETMNFI 700
>UniRef50_O54784 Cluster: Death-associated protein kinase 3; n=16;
Euteleostomi|Rep: Death-associated protein kinase 3 -
Mus musculus (Mouse)
Length = 448
Score = 94.7 bits (225), Expect = 6e-18
Identities = 59/184 (32%), Positives = 98/184 (53%), Gaps = 16/184 (8%)
Query: 57 REFEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFL 116
RE +L++++H NI+ L + E + V+++EL +GG LF+ L + E+ L E E
Sbjct: 63 REVSILREIRHPNIITLHDVFENKTD--VVLILELVSGGELFDFLAEKES---LTEDEAT 117
Query: 117 LVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSL 176
L+ + G+ +L + H DLKP NIM + KL DFG A ++ +F ++
Sbjct: 118 QFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNI 177
Query: 177 YGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETM 236
+GT E++ P++ V +P+ G D+WSIGV Y + +G PF G +ET+
Sbjct: 178 FGTPEFVAPEI----VNYEPL----GLEADMWSIGVITYILLSGASPFL---GETKQETL 226
Query: 237 FYIT 240
I+
Sbjct: 227 TNIS 230
>UniRef50_UPI00015B6294 Cluster: PREDICTED: similar to myosin light
chain kinase isoform-I; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to myosin light chain kinase
isoform-I - Nasonia vitripennis
Length = 908
Score = 94.3 bits (224), Expect = 7e-18
Identities = 65/209 (31%), Positives = 107/209 (51%), Gaps = 19/209 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LGKG G V + V K + + A K + VQ E +++ ++H +++L+A
Sbjct: 219 LGKGRYGVVRRVVEKKSEKSFAAKIVRTVKTSDRKQVQ-EEMKIMNLLRHPKLLRLMAAF 277
Query: 78 EEQEGRGKVIVMELCTGGSLFN--ILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
E + V+V E +GG LF + DD + L E + +L + + G++++ NN+V
Sbjct: 278 ESP--KEIVMVTEYISGGELFERVVADD----FTLTEKDSILFMRQICEGVRYMHKNNVV 331
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
H DLKP NIM + + KL DFG A+ L + L+GT E++ P++ + +
Sbjct: 332 HLDLKPENIMCHTRT--SHRIKLIDFGLAQILSPSQPVRVLFGTPEFIPPEI----INYE 385
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P+ G D+WS+GV Y + TG PF
Sbjct: 386 PI----GTESDMWSVGVICYVLLTGLSPF 410
>UniRef50_UPI000155ED1B Cluster: PREDICTED: similar to
serine/threonine kinase PSKH2; n=1; Equus caballus|Rep:
PREDICTED: similar to serine/threonine kinase PSKH2 -
Equus caballus
Length = 521
Score = 94.3 bits (224), Expect = 7e-18
Identities = 66/211 (31%), Positives = 109/211 (51%), Gaps = 17/211 (8%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
+++G G V + K +P A+K + + E VLK+V+H IV+L+
Sbjct: 203 ALIGAGKFSKVVRVEQKTTKKPFAIKVM-ETRVREGREACESELTVLKRVRHRYIVQLME 261
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
I E Q+ IVMEL TGG LF+ L + E + + +L + G+++L +
Sbjct: 262 IFEAQDR--VYIVMELATGGELFDRLMTQRS---FTEQDAVRILHMVADGIRYLHALRIT 316
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV--SLYGTEEYLHPDMYERAVL 193
HRDLKP N++ Y + + +TDFG A + + +L GT EY+ P++ +L
Sbjct: 317 HRDLKPENLL-YYHPGAESKILITDFGLAHSGNKSGDWTMRTLCGTPEYIAPEV----LL 371
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
RKP + + VD+W++GV + + +G LPF
Sbjct: 372 RKP----YTSAVDMWALGVITFVLLSGFLPF 398
>UniRef50_UPI0000E80D72 Cluster: PREDICTED: similar to myosin light
chain kinase (MLCK); n=1; Gallus gallus|Rep: PREDICTED:
similar to myosin light chain kinase (MLCK) - Gallus
gallus
Length = 921
Score = 94.3 bits (224), Expect = 7e-18
Identities = 66/223 (29%), Positives = 108/223 (48%), Gaps = 18/223 (8%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLG G G V + + G +A K +V+ E ++ ++ H N+++L
Sbjct: 618 VLGGGRFGQVHKCTEVSTGLNLAAKIIKVKGAKEKEEVK-NEINIMNQLNHVNLIQLYDA 676
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E + ++ME GG LF+ + D EN Y L E + +L + + G+ +L + ++H
Sbjct: 677 FEAKNN--VTLIMEYLDGGELFDRITD-EN-YNLTELDAILFTKQICEGVHYLHQHYILH 732
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
DLKP NI+ +N G K+ DFG AR + E+ +GT E+L P++ + P
Sbjct: 733 LDLKPENIL-CVNHTG-NQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSYP 790
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
D+WS+GV Y + +G PF G + ETM Y+
Sbjct: 791 --------TDMWSVGVITYMLLSGLSPFL---GETDAETMNYV 822
>UniRef50_UPI0000E7FBCB Cluster: PREDICTED: similar to NIMA (never
in mitosis gene a)-related kinase 5; n=1; Gallus
gallus|Rep: PREDICTED: similar to NIMA (never in mitosis
gene a)-related kinase 5 - Gallus gallus
Length = 816
Score = 94.3 bits (224), Expect = 7e-18
Identities = 62/209 (29%), Positives = 101/209 (48%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSH-MRPHDVQMREFEVLKKVKHENIVKLLAI 76
+G+G+ G +F K + E +K + ++ + +E +L K+KH NIV A
Sbjct: 10 IGEGSFGKIFLAKAKVDNEQCVIKEIDLTKMPVKEKEASQKEVILLAKMKHANIVTFYA- 68
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
QE IVME C GG L ++ +E + L + G+KH+ D ++H
Sbjct: 69 -SLQEENKLYIVMEYCDGGDLMKRINMQHGVL-FEEDQILSWFVQIALGLKHIHDRKILH 126
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAVLRK 195
RD+K NI +++ +G KL DFG AR+L + +F + GT YL P++ E
Sbjct: 127 RDIKSQNI--FLSSNGKVA-KLGDFGIARQLNDTTEFAYTCVGTPYYLSPEICE------ 177
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + D+WS+G LY + + PF
Sbjct: 178 --NRPYNNKTDIWSLGCVLYELCALKHPF 204
>UniRef50_UPI0000ECB019 Cluster: UPI0000ECB019 related cluster; n=1;
Gallus gallus|Rep: UPI0000ECB019 UniRef100 entry -
Gallus gallus
Length = 789
Score = 94.3 bits (224), Expect = 7e-18
Identities = 66/223 (29%), Positives = 108/223 (48%), Gaps = 18/223 (8%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLG G G V + + G +A K +V+ E ++ ++ H N+++L
Sbjct: 486 VLGGGRFGQVHKCTEVSTGLNLAAKIIKVKGAKEKEEVK-NEINIMNQLNHVNLIQLYDA 544
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E + ++ME GG LF+ + D EN Y L E + +L + + G+ +L + ++H
Sbjct: 545 FEAKNN--VTLIMEYLDGGELFDRITD-EN-YNLTELDAILFTKQICEGVHYLHQHYILH 600
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
DLKP NI+ +N G K+ DFG AR + E+ +GT E+L P++ + P
Sbjct: 601 LDLKPENIL-CVNHTG-NQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSYP 658
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
D+WS+GV Y + +G PF G + ETM Y+
Sbjct: 659 --------TDMWSVGVITYMLLSGLSPFL---GETDAETMNYV 690
>UniRef50_Q5BJ15 Cluster: Wu:fc83c01 protein; n=4; Danio rerio|Rep:
Wu:fc83c01 protein - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 318
Score = 94.3 bits (224), Expect = 7e-18
Identities = 64/224 (28%), Positives = 109/224 (48%), Gaps = 22/224 (9%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHE 68
+ W + +G+G G V+ +N + GE +A+K Q + + E ++ + +KH
Sbjct: 51 FKWQRGNKIGEGQYGKVYTCINVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHP 110
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
N+V+ +E +E I ME C G+L + + GLQE+ L + +T +
Sbjct: 111 NLVRYFGVELHREEM--YIFMEYCDEGTLEEV-----SRLGLQEHVIRLYSKQITTAINV 163
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-----SLYGTEEYL 183
L ++ +VHRD+K NI ++ G KL DFG + +L+ Q + S GT Y+
Sbjct: 164 LHEHGIVHRDIKGANI--FLTSSGLI--KLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYM 219
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPY 227
P++ RA G+ G D+WS+G L + TG+ P+ Y
Sbjct: 220 APEVITRAK-----GEGHGRAADIWSLGCVLIEMVTGKRPWHEY 258
>UniRef50_Q4XQ94 Cluster: Protein kinase, putative; n=1; Plasmodium
chabaudi|Rep: Protein kinase, putative - Plasmodium
chabaudi
Length = 296
Score = 94.3 bits (224), Expect = 7e-18
Identities = 61/214 (28%), Positives = 105/214 (49%), Gaps = 16/214 (7%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVK 66
N + +LGKG+ G V +K+ G A+K ++ R D Q +RE E+LK +
Sbjct: 67 NEQYKGIKILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLD 126
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
H NI+KL E+ +V ++ +GG LF+ + + Y E + +++ + +G+
Sbjct: 127 HINIMKLYEFFEDNNYY--YLVSDVYSGGELFDEIISRKRFY---EVDAARIIKQVLSGI 181
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPD 186
++ NN+VHRDLKP NI+ K+ DFG + + ++ GT Y+ PD
Sbjct: 182 TYMHKNNVVHRDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPD 241
Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATG 220
+ + ++ D+WS GV LY + +G
Sbjct: 242 V---------LHGTYDEKCDIWSCGVILYILLSG 266
>UniRef50_Q0KI87 Cluster: CG11870-PA, isoform A; n=3; Drosophila
melanogaster|Rep: CG11870-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 1427
Score = 94.3 bits (224), Expect = 7e-18
Identities = 62/209 (29%), Positives = 101/209 (48%), Gaps = 18/209 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKLLA 75
LG+G G V G+NK G+ VA+KT + D+ RE +++ V H NI+ +
Sbjct: 76 LGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNIIHIYE 135
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E +E V+VME GG L++ L + + L E E + + + + + +
Sbjct: 136 VFENRE--KMVLVMEFAAGGELYDYLSERK---VLTEEEARRIFRQVATAVYYCHKHKIC 190
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLK NI+ ++E G K+ DFG + ++ + G+ Y P++ E +
Sbjct: 191 HRDLKLENIL--LDEKGNA--KIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQ- 245
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
G VD WS+GV LY + G +PF
Sbjct: 246 ------GPEVDCWSLGVLLYTLVYGSMPF 268
>UniRef50_O43945 Cluster: MEKK-related kinase; n=4; Leishmania|Rep:
MEKK-related kinase - Leishmania major
Length = 1122
Score = 94.3 bits (224), Expect = 7e-18
Identities = 67/236 (28%), Positives = 112/236 (47%), Gaps = 21/236 (8%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFN--QLSHMRPHDVQMREFEVLKKVKHENIVKLL 74
++G G VF GV+ GE VA+K + ++ ++ + EF +LK + H NIV
Sbjct: 318 LIGAGGFAKVFAGVDTIRGELVAIKEIDISRVDDVKALNAIEAEFALLKSLHHPNIVSYS 377
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNN 133
E + + I MEL G S ++L +G L E +V + ++ +
Sbjct: 378 LFEHSKSQKVCRIAMELLAGDSTLHLLQK----FGPLTEAVLRIVARSVLRAIRFIHKEG 433
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVS-LYGTEEYLHPDMYERAV 192
+ HRD+KP NI+ ++ G KL DFG ++ + E + S + GT Y+ P+ +
Sbjct: 434 IFHRDIKPANIL--VSHRGEV--KLCDFGCSKRVSELNKAASCIIGTPVYMAPEFIKGEA 489
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGVI 248
K D+WS+ L+ ++TG LP+ G + N MFY+TT S ++
Sbjct: 490 NHK---------ADIWSMACALFELSTGLLPWYHSGAKDNLPLMFYLTTTSESPMV 536
>UniRef50_A0BX79 Cluster: Chromosome undetermined scaffold_134,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_134,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 596
Score = 94.3 bits (224), Expect = 7e-18
Identities = 65/224 (29%), Positives = 109/224 (48%), Gaps = 18/224 (8%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKVKHEN 69
+S +G+G+ VF+G E VA+K ++ ++R + M +E E+L+++ H N
Sbjct: 13 YSLIREIGQGSFARVFRGKLDGRQEDVAIKMISK-QNVRNESMSMIEKEIEILRQLDHPN 71
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
I+KL+ + Q +V E C G L + L E E +++ L ++ +
Sbjct: 72 IIKLIDFKRTQNHY--YLVFEYCENGDLDAYIRKYSPNGKLPEEEVRRIVQQLAQALQQM 129
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189
+VHRDLK NI+ N KL DFG A+ ++E++ S GT + P++ +
Sbjct: 130 YKLRIVHRDLKLANILVSKNFQ----IKLADFGFAKYMEEDQYLTSYCGTPLTMAPEILQ 185
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF-RPYGGRRN 232
R K + D+WS+GV +Y + G+ PF P GG N
Sbjct: 186 R--------KQYNEKCDVWSVGVIMYQMIYGRSPFVPPKGGNIN 221
>UniRef50_Q39008 Cluster: Mitogen-activated protein kinase kinase
kinase 1; n=7; Magnoliophyta|Rep: Mitogen-activated
protein kinase kinase kinase 1 - Arabidopsis thaliana
(Mouse-ear cress)
Length = 608
Score = 94.3 bits (224), Expect = 7e-18
Identities = 63/217 (29%), Positives = 109/217 (50%), Gaps = 21/217 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSH--MRPHDVQMREFEV--LKKVKH 67
W +LG+G+ G+V++G++ +G+ AVK + L +Q E E+ L +++H
Sbjct: 333 WQKGQLLGRGSFGSVYEGIS-GDGDFFAVKEVSLLDQGSQAQECIQQLEGEIKLLSQLQH 391
Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
+NIV+ ++ G I +EL T GSL + Y L++ L + G+K
Sbjct: 392 QNIVRYRGTAKD--GSNLYIFLELVTQGSLLKLYQ----RYQLRDSVVSLYTRQILDGLK 445
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
+L D +HRD+K NI+ D KL DFG A+ + + S GT ++ P+
Sbjct: 446 YLHDKGFIHRDIKCANILV----DANGAVKLADFGLAK-VSKFNDIKSCKGTPFWMAPE- 499
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
V+ + +G+ D+WS+G T+ + TGQ+P+
Sbjct: 500 ----VINRKDSDGYGSPADIWSLGCTVLEMCTGQIPY 532
>UniRef50_UPI000150A88D Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 669
Score = 93.9 bits (223), Expect = 1e-17
Identities = 65/233 (27%), Positives = 121/233 (51%), Gaps = 20/233 (8%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKT-FNQ-LSHMRPHDVQMREFEVLKK 64
S+N + LGKG G V+ ++ N + AVK F+Q L + + +++ +E + K
Sbjct: 28 SKNNTYRIIKTLGKGQYGTVYLAIDSNQQQQFAVKQIFSQSLINKKLNELLNQELTIQKI 87
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
+K ++ V+++ +Q + +I+ E C GG L + + Y L E + + L+ L
Sbjct: 88 IKSQHTVQVIEDFFDQNFKTHIIIQEYCDGGDLEQYVK--KYKY-LPEAQAISYLKQLLQ 144
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
K L + +HRD+KP NI+ I++ KL DFG A++L +++ + GT +
Sbjct: 145 AFKELHFHKCMHRDIKPSNIL--ISQG---LIKLGDFGFAKQLNDQDITKTALGTTITMA 199
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
P+++ + + + D++S+G+ Y++ GQ PF+P G N ET+F
Sbjct: 200 PEVFYQ--------QEYSYEADMFSLGIVFYYMLFGQYPFKPQG--LNPETLF 242
>UniRef50_UPI0000F2C92F Cluster: PREDICTED: similar to
serine/threonine kinase PSKH2; n=1; Monodelphis
domestica|Rep: PREDICTED: similar to serine/threonine
kinase PSKH2 - Monodelphis domestica
Length = 513
Score = 93.9 bits (223), Expect = 1e-17
Identities = 64/215 (29%), Positives = 113/215 (52%), Gaps = 17/215 (7%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
++ +++G+G V + + +P A+K + S + E VL++V H NIV
Sbjct: 193 YTIQALIGRGRFSKVVRVEQRVTKKPFAIKMV-ETSLKEGREACESELSVLRRVSHCNIV 251
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
+L+ I E Q+ IVMEL TGG LF+ + + T+ E + +++L+ + G+++L
Sbjct: 252 QLIEIFEAQDR--VYIVMELATGGELFDRII-AQGTF--TERDAVIILKMVVDGVRYLHS 306
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFG--AARELQEEEQFVSLYGTEEYLHPDMYE 189
+ HRDLKP N++ Y + + +TDFG ++ + +L GT EY+ P++
Sbjct: 307 LQITHRDLKPENLL-YYHPGAESKILITDFGLSSSGHKNGDWSMSTLCGTPEYIAPEILS 365
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
R K + VD+W++GV Y + +G LPF
Sbjct: 366 R--------KPYTNAVDMWALGVIAYVLLSGSLPF 392
>UniRef50_UPI0000DB7011 Cluster: PREDICTED: similar to CG33519-PB
isoform 1; n=1; Apis mellifera|Rep: PREDICTED: similar to
CG33519-PB isoform 1 - Apis mellifera
Length = 2794
Score = 93.9 bits (223), Expect = 1e-17
Identities = 68/236 (28%), Positives = 109/236 (46%), Gaps = 22/236 (9%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
N ++ LG+G G + V ++ G+ A K + ++P+ E EV+ + H
Sbjct: 1757 NELYDLGDELGRGTQGVTYHAVERSTGKNYAAKVMHGKGELKPY--MHNEIEVMNNLNHR 1814
Query: 69 NIVKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
KLL + + E V +V+EL GG L + L + Y E E + L G++
Sbjct: 1815 ---KLLRLHDAYETDTSVTLVIELAAGGELVDTLT--KQAY-YTEAEIAGYIRQLLWGLE 1868
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
++ N H L G+++ I+ G K+ DFG AR + + LYG EY+ P++
Sbjct: 1869 YMHSNQYAHLGLTLGDLL--ISHTGGDDLKICDFGLARRISHAKMMTLLYGMPEYVAPEV 1926
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
G SF A D+WS+G+ Y + +G PFR G +KET+ I K
Sbjct: 1927 TNNE------GVSFSA--DMWSVGIITYILLSGISPFR---GNNDKETLMKIREGK 1971
Score = 67.3 bits (157), Expect = 1e-09
Identities = 56/228 (24%), Positives = 100/228 (43%), Gaps = 15/228 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
+S S + +G V +GV+K + K +L V REFE L+ ++HE I
Sbjct: 2473 YSFISEIYRGQFSVVAKGVDKGTDRIIVAKIL-ELKTETEKQVN-REFEALRSLRHERIA 2530
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
L A + Q V ++E G +IL + + E + + + G+++L
Sbjct: 2531 MLEAAYKAQGSPIAVFILEKLQGA---DILTYFSSRHEYTENCVAVAITQILDGLQYLHW 2587
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERA 191
H D++P NI+ ++ + KL D G+AR + + V G EY P++Y
Sbjct: 2588 RGYSHLDIQPDNIV--MSNVRSVQVKLVDMGSARLVSKLGTLVPKAGHPEYRAPEVYN-- 2643
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
+P D+W +GV +Y + +G PFR ++ + ++
Sbjct: 2644 --EEPAHPQ----TDIWMVGVLMYILLSGISPFRGKDPDETRQNILFV 2685
>UniRef50_UPI00006CFB74 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 858
Score = 93.9 bits (223), Expect = 1e-17
Identities = 64/223 (28%), Positives = 104/223 (46%), Gaps = 22/223 (9%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ---MREFEVLKKV 65
NY +S LG+G G VFQGVNK E VA+K +Q + ++ RE E LKK+
Sbjct: 11 NYKFSINYCLGQGEYGKVFQGVNKITNEDVAIKQIDQRMVQQDQYIKQSLQREIEALKKI 70
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYE--FLLVLEHL 122
KH N+++L + I+ E C G L + + ++ EYE L + +
Sbjct: 71 KHPNVIELKDV--YYSDNYIYIIQEFCQDGELKHYIQTIQKSNMPFDEYEKICLEIAYQI 128
Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEE 181
T GM+ + +++HRDLKP NI+ + K+ DFG + + + S G+
Sbjct: 129 TQGMQTVHRMDIIHRDLKPQNILVH-----NKKIKIIDFGFCKSFDNQAHMIKSAVGSPY 183
Query: 182 YLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
Y+ P + + + D+WS G+ Y + +LP+
Sbjct: 184 YMSPQILSKI--------PYTYKTDIWSFGMIFYELVFKKLPY 218
>UniRef50_UPI00004983FA Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 396
Score = 93.9 bits (223), Expect = 1e-17
Identities = 63/214 (29%), Positives = 105/214 (49%), Gaps = 14/214 (6%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ G VFQ K+N + AVK + ++ + ++ RE EVL+++ H+NI+K E
Sbjct: 131 IGSGSFGKVFQIKRKSNNKINAVKIID-ITQKKKSEIAQRESEVLEQIHHQNIIK--KYE 187
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
Q R I+ME G +L L ++ + E E ++++ + + +L N ++HR
Sbjct: 188 TIQSQRFMYIIMEYIEGLTLEQYLQLKQH-HTFNENEIKIIIKQVFNAINYLHSNKIIHR 246
Query: 138 DLKPGNIM---KYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
DLK NIM K E + DFG + L+ +E ++ GT Y P + +
Sbjct: 247 DLKLENIMIRGKTNEEYKKLNIVVMDFGLGKILETKEYTLTKCGTSNYTSPQILQS---- 302
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
G G D+W GV L++++ G PF G
Sbjct: 303 ---GPYDGFKTDIWCCGVMLFYMSIGMFPFNQEG 333
>UniRef50_A7UAR9 Cluster: Checkpoint kinase 2; n=1; Oncorhynchus
mykiss|Rep: Checkpoint kinase 2 - Oncorhynchus mykiss
(Rainbow trout) (Salmo gairdneri)
Length = 507
Score = 93.9 bits (223), Expect = 1e-17
Identities = 73/263 (27%), Positives = 124/263 (47%), Gaps = 22/263 (8%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR----EFEVL 62
SE Y+ T +G G G V + + VAVKT N+ R E ++L
Sbjct: 175 SEKYL--ITRKIGAGVCGEVKLAFERATCKKVAVKTINKKDFPASVGTATRNAEREIQIL 232
Query: 63 KKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHL 122
+++ H ++K + + IV+EL GG LF D ++ ++E L +
Sbjct: 233 QRINHPCLIKTEDFFQTDDSY--YIVLELMEGGELF---DRVKSKNQIEESIAELYFYQM 287
Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEY 182
+++L +N ++HRDLKP N++ ++D K+TDF ++ L+E +L GT Y
Sbjct: 288 LKAVEYLHNNGIIHRDLKPENVL-LSSQDDVCVIKITDFNQSKILEESALMRTLCGTPTY 346
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTK 242
L P+++ AV VG + VD WS+GV L+ G PF P N +T + +
Sbjct: 347 LAPEVFTDAV---TVG--YSRAVDAWSLGVVLFVCLAGYPPFHP-----NAQTGLSVRDQ 396
Query: 243 KASGVISGTQTTENGPIDWAREL 265
G+ + + +G D A+++
Sbjct: 397 ITQGIYTFIPSKWDGISDDAKDV 419
>UniRef50_Q16SX1 Cluster: Mitogen activated protein kinase kinase
kinase 4, mapkkk4, mekk4; n=1; Aedes aegypti|Rep: Mitogen
activated protein kinase kinase kinase 4, mapkkk4, mekk4
- Aedes aegypti (Yellowfever mosquito)
Length = 1431
Score = 93.9 bits (223), Expect = 1e-17
Identities = 69/238 (28%), Positives = 115/238 (48%), Gaps = 20/238 (8%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKV 65
S N+ W +G+G G V+ VN + GE +A+K Q E ++ + +
Sbjct: 1135 SVNFSWHRGIKIGQGRFGKVYTAVNNSTGELMAMKEIAIQPGETSAIRKVAEELKIFEGI 1194
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
H N+VK +E +E +I MELC G+L +++ E GL E + L +G
Sbjct: 1195 NHRNLVKYYGVEVHRE--ELLIFMELCPEGTLESLV---ELNGGLPEPQTRRYTIQLLSG 1249
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEE----QFVSLYGTEE 181
+K L + +VHRD+K NI ++ +DG KL DFG+A ++Q + GT+
Sbjct: 1250 VKELHRHGVVHRDIKTANI--FLTKDG-NCLKLGDFGSAVKIQAHTTMPGELKGYVGTQA 1306
Query: 182 YLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
Y+ P+ V K + G D+WS+G + +++G+ P+ Y N + MF +
Sbjct: 1307 YMAPE-----VFTKTNSEGHGRAADIWSVGCVVIEMSSGKRPW--YQFDSNFQIMFKV 1357
>UniRef50_A0C8K1 Cluster: Chromosome undetermined scaffold_158,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_158,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 873
Score = 93.9 bits (223), Expect = 1e-17
Identities = 71/229 (31%), Positives = 116/229 (50%), Gaps = 23/229 (10%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMR-PHDVQMREFEVLKKVKHENIVKLL- 74
+LG+G+ G V++G+N G VA+K ++ + + +E +LKK+KHENIVK +
Sbjct: 19 LLGRGSIGTVYKGLNLELGTLVAIKQVSRATLKEDQYKALQQEIYLLKKLKHENIVKYID 78
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
IE +Q I++E GSL +IL + E + ++ + G+++L +
Sbjct: 79 CIETDQFLN---IILEYIESGSLASIL---KKFGSFPESLVAIYVKQVLKGLEYLHQQGI 132
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEE-EQFVSLYGTEEYLHPDMYERAVL 193
VHRD+K NI+ +DGT KL DFG A L E+ Q ++ GT ++ P++ E
Sbjct: 133 VHRDIKGANIL--TPKDGTV--KLADFGVATTLSEDTTQSNNIVGTPYWMAPEVIE---- 184
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTK 242
+ + D+WS+G T+ + TG PY R MF I +
Sbjct: 185 ---MSGHLSTSCDIWSLGCTVIELLTGN---PPYFDRLQYAAMFQIVQR 227
>UniRef50_A0BFB3 Cluster: Chromosome undetermined scaffold_103,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_103,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 418
Score = 93.9 bits (223), Expect = 1e-17
Identities = 64/207 (30%), Positives = 100/207 (48%), Gaps = 12/207 (5%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+GKG+ V + V+ N A K + D+ M E ++ + H+NIV+LL I
Sbjct: 132 IGKGSYSNVLKVVSYQNKNMYACKCIEPNDNFSEQDI-MNEIQIHSLINHQNIVRLLGIS 190
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+ Q R +++EL G +L N + L E E + +L+ L + HL NN++HR
Sbjct: 191 KTQ--RHFYLLLELPNGDTLKNYMC---KKIKLSEEEIVGILKQLLQAIDHLHSNNIIHR 245
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP NI+ + D T KL DFG A L + + GT Y+ P++ L
Sbjct: 246 DIKPENIILQ-HSDDQTLIKLIDFGLAANLNDPHIQYKVCGTSGYVAPEVINNNGL---- 300
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPF 224
+G D++S GV LY + T + F
Sbjct: 301 -TPYGTKCDIFSCGVILYQLLTHKYLF 326
>UniRef50_Q9P8J0 Cluster: Map kinase kinase; n=1; Pneumocystis
carinii|Rep: Map kinase kinase - Pneumocystis carinii
Length = 398
Score = 93.9 bits (223), Expect = 1e-17
Identities = 60/212 (28%), Positives = 100/212 (47%), Gaps = 14/212 (6%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG+G +G+V + + KN G A+KT ++ +RE + + E IV+
Sbjct: 117 LGEGISGSVSKCILKNTGTLFALKTILVDTNPEIQQQILRELSINRTCSSEYIVQYYGTF 176
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPE-NTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
++ + ME C GGSL + N + EY L + E+ G+ +L ++H
Sbjct: 177 VDEASSNISMAMEYCAGGSLDRLYKKVRANGARIGEYPILKIAENALKGLNYLHTRKIIH 236
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RD+KP NI+ + KL DFG + EL + GT Y+ P+ +
Sbjct: 237 RDIKPSNILMTLEGQA----KLCDFGVSGEL-VSSMAKTFTGTSYYMAPERIK------- 284
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
G+++ T D+WS+G+TL ++ + PF P G
Sbjct: 285 -GETYSITSDIWSLGLTLMEISQNRFPFPPEG 315
>UniRef50_Q756N1 Cluster: AER223Cp; n=1; Eremothecium gossypii|Rep:
AER223Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 902
Score = 93.9 bits (223), Expect = 1e-17
Identities = 60/213 (28%), Positives = 105/213 (49%), Gaps = 21/213 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
++ V+GKGA G V++ VN+ + +A+K + H+ M E ++LK +KHENIV
Sbjct: 19 YALKQVIGKGAYGVVYKAVNRATDQVIAIKAIEYENEEELHE-HMLEIDLLKNLKHENIV 77
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
K Q I++E C GSL +++ L E + + G+++L D
Sbjct: 78 KYHGF--IQSSHELYILLEYCIRGSLRDLI----KKEALSEAKAKTYVRQTLRGLQYLHD 131
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERA 191
++HRD+K N++ + E+G KL DFG + + ++ G+ ++ P++
Sbjct: 132 QGVIHRDIKAANLL--LTENGVV--KLADFGVSTRV--NNMAMTYAGSPNWMAPEVM--- 182
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+GK D+WS+G T+ + TG PF
Sbjct: 183 -----LGKGASTVSDIWSLGATVVELLTGNPPF 210
>UniRef50_A5E6H6 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 1534
Score = 93.9 bits (223), Expect = 1e-17
Identities = 60/221 (27%), Positives = 117/221 (52%), Gaps = 21/221 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKH 67
E+++W ++G+G+ G+V+ +N GE +A+K + + D +E + +K + H
Sbjct: 1245 ESFLWIKGELIGRGSYGSVYLALNVTTGEMIALKQVFVQTQIDVEDFN-KEIKNMKDLDH 1303
Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGM 126
NIV+ L E + + ME GGS+ + L +YG E V + + G+
Sbjct: 1304 ANIVQYLGCERQTNMY--CLFMEYVAGGSIASCL----KSYGRFDETLIKFVTKQVLLGL 1357
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQE---EEQFVSLYGTEEYL 183
K+L +NN++HRDLK N++ ++ DGT K++DFG ++++ + +S+ GT ++
Sbjct: 1358 KYLHNNNIIHRDLKADNLL--LDLDGTC--KISDFGISKKISDIYANNANMSMKGTIFWM 1413
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ + + + A VD+WS+G + + G+ P+
Sbjct: 1414 APEVIDNE------AQGYSAKVDIWSLGCVVLEMFAGKRPW 1448
>UniRef50_Q9BYT3 Cluster: Serine/threonine-protein kinase 33; n=26;
Eumetazoa|Rep: Serine/threonine-protein kinase 33 - Homo
sapiens (Human)
Length = 514
Score = 93.9 bits (223), Expect = 1e-17
Identities = 67/222 (30%), Positives = 108/222 (48%), Gaps = 21/222 (9%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHEN 69
+++ +LGKG+ G V + +K A+K N + + + RE +LK VKHE+
Sbjct: 115 IYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEH 174
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
I+ L + E + +VMELC G L ILD + E E +++ L + + +L
Sbjct: 175 IIHLEQVFETP--KKMYLVMELCEDGELKEILDRKGH---FSENETRWIIQSLASAIAYL 229
Query: 130 RDNNLVHRDLKPGNIMKYI-----NEDGTTTYKLTDFGAA--RELQEEEQFVSLYGTEEY 182
+N++VHRDLK NIM N + K+TDFG A ++ + E + GT Y
Sbjct: 230 HNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIY 289
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P++ + D+WSIGV +Y + G+ PF
Sbjct: 290 MAPEVIS--------AHDYSQQCDIWSIGVVMYMLLRGEPPF 323
>UniRef50_Q16566 Cluster: Calcium/calmodulin-dependent protein
kinase type IV; n=36; Eumetazoa|Rep:
Calcium/calmodulin-dependent protein kinase type IV -
Homo sapiens (Human)
Length = 473
Score = 93.9 bits (223), Expect = 1e-17
Identities = 67/222 (30%), Positives = 110/222 (49%), Gaps = 20/222 (9%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
S LG+GAT V++ K +P A+K + + + E VL ++ H NI+KL
Sbjct: 50 SELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKK---IVRTEIGVLLRLSHPNIIKLKE 106
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
I E +V+EL TGG LF+ + E Y E + ++ + + +L +N +V
Sbjct: 107 IFETPTEIS--LVLELVTGGELFDRI--VEKGY-YSERDAADAVKQILEAVAYLHENGIV 161
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLKP N++ Y K+ DFG ++ ++ + ++ GT Y P+ +LR
Sbjct: 162 HRDLKPENLL-YATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPE-----ILR- 214
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
G ++G VD+WS+G+ Y + G F P+ R + MF
Sbjct: 215 --GCAYGPEVDMWSVGIITYILLCG---FEPFYDERGDQFMF 251
>UniRef50_Q9UIK4 Cluster: Death-associated protein kinase 2; n=4;
Amniota|Rep: Death-associated protein kinase 2 - Homo
sapiens (Human)
Length = 370
Score = 93.9 bits (223), Expect = 1e-17
Identities = 60/184 (32%), Positives = 97/184 (52%), Gaps = 16/184 (8%)
Query: 57 REFEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFL 116
RE +L++V H N++ L + E + V+++EL +GG LF+ L E+ L E E
Sbjct: 73 REVSILRQVLHHNVITLHDVYENRTD--VVLILELVSGGELFDFLAQKES---LSEEEAT 127
Query: 117 LVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSL 176
++ + G+ +L + H DLKP NIM KL DFG A E+++ +F ++
Sbjct: 128 SFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNI 187
Query: 177 YGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETM 236
+GT E++ P++ V +P+ G D+WSIGV Y + +G PF G +ET+
Sbjct: 188 FGTPEFVAPEI----VNYEPL----GLEADMWSIGVITYILLSGASPFL---GDTKQETL 236
Query: 237 FYIT 240
IT
Sbjct: 237 ANIT 240
>UniRef50_UPI000155CD84 Cluster: PREDICTED: similar to
Mitogen-activated protein kinase kinase kinase 15
(MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15);
n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
Mitogen-activated protein kinase kinase kinase 15
(MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15) -
Ornithorhynchus anatinus
Length = 1407
Score = 93.5 bits (222), Expect = 1e-17
Identities = 65/214 (30%), Positives = 110/214 (51%), Gaps = 17/214 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+LGKG G V+ G + +N +A+K + + E + K +KH NIV+ L
Sbjct: 729 ILGKGTYGVVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKYLKHRNIVRYLGS 787
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNLV 135
E +G K+ ME GGSL +L + +G ++E + + G+K+L +N +V
Sbjct: 788 VSE-DGYIKIF-MEQVPGGSLSALL---RSKWGPMKEPTIKFYTKQILEGLKYLHENQIV 842
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLR 194
HRD+K N++ +N K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 843 HRDIKGDNVL--VNTYSGVV-KISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDKG--- 896
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +GA D+WS+G T+ +ATG+ PF G
Sbjct: 897 -PRG--YGAPADIWSLGCTIIEMATGKPPFHELG 927
>UniRef50_UPI0000499847 Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 408
Score = 93.5 bits (222), Expect = 1e-17
Identities = 60/207 (28%), Positives = 101/207 (48%), Gaps = 16/207 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G+G G V + + K E +K + + RE EVL+K HENIVK+ +
Sbjct: 132 IGEGTFGIVRRVIEKETQEEYVMKEITRTKGSAEESGR-RESEVLRKTNHENIVKMKGVF 190
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+ + I+ME GG L + L + + E + ++ + + +K+L +NN++HR
Sbjct: 191 KTNQYL--YIIMEYVRGGELLDALKKEKR---MSEAKIKTIMYQIFSALKYLHENNIIHR 245
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLK N+M KL DFG R + + + + GT Y P++++
Sbjct: 246 DLKLENVMLC---GVNLKVKLADFGFGRIIDQTQAAKTHIGTTTYFAPELFKD------- 295
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPF 224
G G VD+W+ G+ +Y +ATG+ PF
Sbjct: 296 GDYNGTKVDMWAAGIMMYFLATGKHPF 322
>UniRef50_UPI000065E60F Cluster: STE20-like serine/threonine-protein
kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related
serine/threonine-protein kinase) (STE20-related kinase)
(hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor
antigen se20-9).; n=1; Takifugu rubripes|Rep: STE20-like
serine/threonine-protein kinase (EC 2.7.11.1)
(STE20-like kinase) (STE20-related
serine/threonine-protein kinase) (STE20-related kinase)
(hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor
antigen se20-9). - Takifugu rubripes
Length = 1128
Score = 93.5 bits (222), Expect = 1e-17
Identities = 66/215 (30%), Positives = 107/215 (49%), Gaps = 15/215 (6%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENI 70
+W LG GA G VF+ NK NG A K + + D M E ++L H +I
Sbjct: 33 IWDIIGELGDGAFGKVFKAQNKQNGTLAAAKVIDTKTEDELEDY-MVEIDILASCDHHHI 91
Query: 71 VKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
VKLL + GK+ I++E C GG++ I+ + E L E + +V + +L
Sbjct: 92 VKLL---DAFYFEGKLWILIEFCAGGAVDAIMLELERP--LTEPQIRVVCRQTLEALIYL 146
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMY 188
+N ++HRDLK GNI+ +N + KL DFG +A+ + ++ S GT ++ P++
Sbjct: 147 HENKIIHRDLKAGNILLSLNGE----VKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEV- 201
Query: 189 ERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + + D+WS+GVTL +A + P
Sbjct: 202 --VMCETSKDRPYDYKADIWSLGVTLIELAQIEPP 234
>UniRef50_Q238Z8 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1005
Score = 93.5 bits (222), Expect = 1e-17
Identities = 67/223 (30%), Positives = 107/223 (47%), Gaps = 18/223 (8%)
Query: 5 RGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ--LSHMRPHDVQMREFEVL 62
+ +E ++ +LG+GA G + + E + K + +S + Q +E +L
Sbjct: 13 QAAEYELYKRIKLLGEGAFGKAYLVEDLRTHELLVQKQMDMKAMSTEEKRETQ-KEARIL 71
Query: 63 KKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHL 122
+++ H NIVK + ++G+ I+ME GG L ++ D Y LQE + L +
Sbjct: 72 QQLNHPNIVKFKDVYTTKKGK-LCIIMEYADGGDLAKVVKDARGKY-LQEKQILDWFTQI 129
Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEE-EQFVSLYGTEE 181
MKH+ D ++HRDLK NI N KL DFG AR L + E+ ++ GT
Sbjct: 130 CLAMKHVHDRKIIHRDLKGQNIFLTRNH----IVKLGDFGIARVLSKTVEKAKTMVGTPY 185
Query: 182 YLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
YL P++ E K + D+WS+GV LY + + PF
Sbjct: 186 YLSPEIIE--------SKPYSFKTDIWSLGVILYELCALKPPF 220
>UniRef50_Q22UA7 Cluster: Protein kinase domain containing protein;
n=7; Eukaryota|Rep: Protein kinase domain containing
protein - Tetrahymena thermophila SB210
Length = 2268
Score = 93.5 bits (222), Expect = 1e-17
Identities = 68/239 (28%), Positives = 124/239 (51%), Gaps = 21/239 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKLLA 75
+G+G G V+ ++ +G +A+K + +M D++ ++E +L+K+ + +IVK
Sbjct: 20 IGQGNYGQVYLVQSQRDGSILAIKNIST-QNMIFEDLEKCLKECTILQKLDNPHIVKFKK 78
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGL-QEYEFLLVLEHLTAGMKHLRDNNL 134
+ + I+ME GG L + + + T L +E + L + G+K++ N +
Sbjct: 79 AINQPNKQMIYIMMEYAEGGDLRKKIKEQKQTGKLFEEDQILDWFIQICLGLKYIHKNKI 138
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ-EEEQFVSLYGTEEYLHPDMYERAVL 193
+HRD+KP NI ++ D K+ DFG ++EL+ +Q S GT YL P+M +
Sbjct: 139 IHRDIKPENI--FLTADNRV--KIGDFGISKELEYTNQQLYSRIGTPYYLAPEMIK---- 190
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGVISGTQ 252
G+ + ++VD+WS+GV LY + + PF + N+ ++Y T KK I+ Q
Sbjct: 191 ----GELYNSSVDIWSLGVVLYELCCLKPPFNSW----NEYIIYYKTYKKPYPPITQAQ 241
Score = 78.2 bits (184), Expect = 5e-13
Identities = 59/211 (27%), Positives = 100/211 (47%), Gaps = 19/211 (9%)
Query: 21 GATGAVFQGVNKNNGEPVAVKTFN--QLSHMRPHDVQMREFEVLKKVKHENIVKLLAIEE 78
G+ G V +K + +A+K + +S + Q E+ L+K+ H IVK
Sbjct: 1196 GSQGQVHLIESKEDSSKLAIKNISTKNMSQQQKRKHQ-DEYRCLQKLDH--IVKFKKAIH 1252
Query: 79 EQEGRGKVIVMELCTGGSLFNILDDP-ENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+ I+ME GG L ++ + +E + L + G+K++ +N ++HR
Sbjct: 1253 CINNQMIQIIMEYTEGGDLQKAIEKQIQIGKPFEEEQILDWFAQICQGLKYIHENKIIHR 1312
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQ-EEEQFVSLYGTEEYLHPDMYERAVLRKP 196
D+KP N+ T K+ DFG A+E + EQ S GT YL P++ +
Sbjct: 1313 DIKPANLFL----TAQNTVKIGDFGVAKEQKYTNEQLSSQIGTPYYLAPEIID------- 1361
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFRPY 227
GK + ++VD+WS+GV LY + + PF +
Sbjct: 1362 -GKPYNSSVDIWSLGVVLYELCCLKPPFNSW 1391
>UniRef50_Q22AY1 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1203
Score = 93.5 bits (222), Expect = 1e-17
Identities = 65/214 (30%), Positives = 114/214 (53%), Gaps = 17/214 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLAI 76
LG+GA+G V++G + G+ VA+K + ++ + + ++ E +LKK+KHENIV I
Sbjct: 22 LGQGASGTVYKGEHIETGQVVAIKLVSTVNIKKENIKSIKKEMHLLKKLKHENIVTY--I 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ Q I++E GSL+ I+ +G QE ++ ++ + G+++L +V
Sbjct: 80 DFIQTENHYAIILEYIESGSLYGII----KKFGPFQESLVIIFIKQVLRGLEYLHRQGIV 135
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLR 194
HRD+K NI+ N + + KLTDFG A L ++++ GT ++ P+ V+
Sbjct: 136 HRDIKGANILTTKN-NKSGVIKLTDFGVATHLADDDKSSTQCVGTPYWMAPE-----VII 189
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
G + D+WS+G T+ + TG P+ YG
Sbjct: 190 DSDG-HISTSCDIWSLGCTIIELLTGNPPY-SYG 221
>UniRef50_A2DLE7 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 326
Score = 93.5 bits (222), Expect = 1e-17
Identities = 65/210 (30%), Positives = 106/210 (50%), Gaps = 18/210 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKVKHENIVKLLA 75
+GKGAT V + +N G+ VA K ++L M+ ++M +E +L+KVKH+NI KL
Sbjct: 28 IGKGATSIVIKAMNNKTGKMVACKVVSRLVLMKLSQLEMFEQELRILEKVKHKNICKLYE 87
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
I +E ++V++ C+ G LF+ + +Q Y +L L + +L +
Sbjct: 88 ILYYEE--VIMVVIKYCSNGDLFDYITSLGTVGEVQCYRIIL---QLAKALSYLHSRKIC 142
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRD+KP NI+ D KL DFG + E+ + GT Y P+ + +V
Sbjct: 143 HRDIKPENIV----FDENMIPKLIDFGISTEVLNNARKNHCSGTFLYCPPECF-NSVQFD 197
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
P+ D+WS+G+TLY + G P++
Sbjct: 198 PM------AADIWSLGMTLYTMLFGCFPWK 221
>UniRef50_A0D2H1 Cluster: Chromosome undetermined scaffold_35, whole
genome shotgun sequence; n=5; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_35,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 674
Score = 93.5 bits (222), Expect = 1e-17
Identities = 63/221 (28%), Positives = 111/221 (50%), Gaps = 22/221 (9%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKT-FNQLSHMRPHDVQM-----REFEVLKK 64
++ +LG GA +V++ K + + A KT F Q PH ++ E LK
Sbjct: 241 LYEQLELLGSGAFASVYKVSRKRDEKYFAAKTYFKQFYDDHPHKERLLSMVYNEITTLKN 300
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
+ H+NI+KL + +E++ +++ME C GG+L++ + + + + +L+ L
Sbjct: 301 IDHQNIMKLYEVIQEKDKL--ILIMEYCAGGTLYSYV---KQKVKFNDKHYAYILKQLCD 355
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
+ + N VHRDLK NIM + KL DFG + E+ E+Q VS GT +L
Sbjct: 356 ALYEMHRLNFVHRDLKLENIM--LESKDYLQLKLVDFGFS-EIINEKQLVSQAGTPGFLP 412
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
P+++ + + A D++S+GV +Y + G +PF+
Sbjct: 413 PEIFRQI--------PYTAKSDIFSLGVIMYLIVAGYMPFK 445
>UniRef50_A0D0C4 Cluster: Chromosome undetermined scaffold_33, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_33,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 595
Score = 93.5 bits (222), Expect = 1e-17
Identities = 64/218 (29%), Positives = 103/218 (47%), Gaps = 20/218 (9%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKVK 66
NY T LG+G G V G + +GE VA+K + DV +E E+LKK++
Sbjct: 8 NYAIGNT--LGEGTFGKVKMGTHLQSGEKVAIKILEKAKFEDESDVYRIAKEIEILKKLR 65
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
H +I+++ I + + ++ME +GG LF + FLL + +G+
Sbjct: 66 HPHIIQIYEIIDTD--KEIYLIMEYASGGELFEYIVKNHRVSEKIACRFLL---QILSGV 120
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPD 186
+++ +VHRDLKP N++ D K+ DFG + + E + G+ Y P+
Sbjct: 121 EYMHKIGIVHRDLKPENLLF----DNNQNIKIVDFGLSNTYKPNELLKTACGSPCYAAPE 176
Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
M + K G +D+WS G+ LY + G LPF
Sbjct: 177 MIQGL-------KYSGYLIDIWSCGIVLYAMLCGYLPF 207
>UniRef50_Q9NRP7 Cluster: Serine/threonine-protein kinase 36; n=28;
Vertebrata|Rep: Serine/threonine-protein kinase 36 -
Homo sapiens (Human)
Length = 1315
Score = 93.5 bits (222), Expect = 1e-17
Identities = 67/212 (31%), Positives = 113/212 (53%), Gaps = 24/212 (11%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQL--SHMRPHDVQMREFEVLKKVKHENIVKLL 74
++G+G+ G V++G K + + VA+K +L S ++Q RE E+++ ++H NIV +L
Sbjct: 9 MIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQ-REIEIMRGLRHPNIVHML 67
Query: 75 -AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
+ E ++E V+V+ G LF IL+D L E + + L + + +L +
Sbjct: 68 DSFETDKE----VVVVTDYAEGELFQILEDDGK---LPEDQVQAIAAQLVSALYYLHSHR 120
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAV 192
++HRD+KP NI+ + + G KL DFG AR + + S+ GT Y+ P++ E
Sbjct: 121 ILHRDMKPQNIL--LAKGGGI--KLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEE-- 174
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + T DLWS+G LY +A G PF
Sbjct: 175 ------RPYDHTADLWSVGCILYELAVGTPPF 200
>UniRef50_UPI0000DB6ED3 Cluster: PREDICTED: similar to CG17528-PC.3;
n=3; Endopterygota|Rep: PREDICTED: similar to
CG17528-PC.3 - Apis mellifera
Length = 670
Score = 93.1 bits (221), Expect = 2e-17
Identities = 63/219 (28%), Positives = 111/219 (50%), Gaps = 20/219 (9%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
V+G+G V +K+ G A+K ++ + E +L++V H NI+ L+A
Sbjct: 326 VIGEGNFAVVRHCSHKSTGVEYAMKIVDKYKCQGKETMWASEVSILRQVCHPNIINLIA- 384
Query: 77 EEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
EQE ++ +VMEL GG LF+ + E E +++ HLT+ + +L +++V
Sbjct: 385 --EQETTDQLFLVMELVKGGDLFDAIAAATK---FSESEASVMIGHLTSALAYLHSHHIV 439
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRD+KP N++ ++ + KL DFG A+ ++ E ++ GT Y+ P++
Sbjct: 440 HRDVKPENLLVEMDGNHVRCLKLCDFGLAQVVR--EPLYTVCGTPTYVAPEILAET---- 493
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKE 234
+G +D+W+ GV LY + G F P+ NK+
Sbjct: 494 ----GYGLKIDVWAAGVILYILLCG---FPPFASPENKQ 525
>UniRef50_UPI00004998B6 Cluster: cell division control protein 7;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: cell division
control protein 7 - Entamoeba histolytica HM-1:IMSS
Length = 1760
Score = 93.1 bits (221), Expect = 2e-17
Identities = 69/220 (31%), Positives = 115/220 (52%), Gaps = 17/220 (7%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTF--NQLSHMRPHDVQMREFEVLKK 64
+E V+S + +G+GA G VFQG+N ++GE VA+K N+ S M+ M E +LKK
Sbjct: 415 NEKSVFSIANSIGRGAYGEVFQGMNADSGEFVAIKQMKVNKKSVMKE---VMEEIRLLKK 471
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
+KH++IV+ +A E G I+ME GSL NI+ + L E + +
Sbjct: 472 LKHKHIVRYIA-STESHG-FLYIIMEYMESGSLLNIV---KKFNHLNESLSAKYIHQVLD 526
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
G+ + D +VHRD+K NI+ + +DG+ K+ DFG + ++ E+ +
Sbjct: 527 GLAFIHDQGIVHRDIKAANIL--VAKDGSV--KIADFGVSVQMNGNEKQEGGSDEDPIGT 582
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P+ V++ G + A D+W++G T+ + TG P+
Sbjct: 583 PNWMAPEVIQMQ-GTTVKA--DIWALGCTIIELITGNPPY 619
>UniRef50_UPI0000660530 Cluster: Serine/threonine-protein kinase
DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM
kinase-like 2).; n=1; Takifugu rubripes|Rep:
Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)
(Doublecortin- like and CAM kinase-like 2). - Takifugu
rubripes
Length = 736
Score = 93.1 bits (221), Expect = 2e-17
Identities = 62/217 (28%), Positives = 105/217 (48%), Gaps = 15/217 (6%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
N + V+G G V + V ++ G+ A+K ++ + E VL++V+H
Sbjct: 472 NEKYQIGKVIGDGNFAVVKECVERSTGQEYALKIIDKARCCGKEHLIENEVAVLRRVRHP 531
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
+I++L+ ++E +VMEL GG LF+ + E + ++ +L +K+
Sbjct: 532 SIIQLIEVDETPSQL--FLVMELVKGGDLFDAITSSTK---YSERDASAMVFNLAGAIKY 586
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMY 188
L N+VHRD+KP N++ DGT + KL DFG A + E ++ GT Y+ P++
Sbjct: 587 LHRMNIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV--EGPLYTVCGTPTYVAPEII 644
Query: 189 ERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+G VD+W+ GV Y + G PFR
Sbjct: 645 AET--------GYGLKVDIWAAGVITYILLCGFPPFR 673
>UniRef50_A7PSB1 Cluster: Chromosome chr14 scaffold_27, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr14 scaffold_27, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 670
Score = 93.1 bits (221), Expect = 2e-17
Identities = 76/239 (31%), Positives = 123/239 (51%), Gaps = 31/239 (12%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVK-----TFNQLSHMRPHDVQMREFEV--LKKVKHEN 69
++G GA G V+ G+N ++GE +AVK T N ++ E EV LK + H N
Sbjct: 66 LIGCGAFGRVYMGMNLDSGELIAVKQVLITTSNATKEKAQAHIRELEEEVKLLKNLSHPN 125
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKH 128
IV+ L I E+E I++E GGS+ ++L +G E + + L G+ +
Sbjct: 126 IVRYLGIVREEETLN--ILLEFVPGGSISSLL----GKFGSFPEAVIRMYTKQLLLGLDY 179
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQF---VSLYGTEEYLHP 185
L +N ++HRD+K NI+ D KL DFGA++++ E S+ GT ++ P
Sbjct: 180 LHNNGIMHRDIKGANIL----VDNKGCIKLADFGASKQVVELATISGAKSMKGTPYWMAP 235
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKA 244
++ +L+ G SF A D+WS+G T+ +ATG+ P+ + +FYI T K+
Sbjct: 236 EV----ILQ--TGHSFSA--DIWSVGCTVIEMATGKPPWSQ--KYQEVAALFYIGTTKS 284
>UniRef50_A5BPZ0 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 715
Score = 93.1 bits (221), Expect = 2e-17
Identities = 62/210 (29%), Positives = 104/210 (49%), Gaps = 18/210 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPH--DVQMREFEVLKKVKHENIVKLLA 75
+G G+ V++ ++ +G VA+K ++ H+ P D +E E+L+ + H NI++LL
Sbjct: 21 IGSGSYAVVWESRHRQSGMVVAIKEIDK-EHLNPKVKDNLFKEIEILRTINHPNIIRLLQ 79
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
E + +V+E C GG L + F+ L AG++ L + L+
Sbjct: 80 AIETSDRI--FLVLEYCDGGDLAAYIHRRGRVPEAVARHFM---RQLAAGLQVLHEKRLI 134
Query: 136 HRDLKPGNIMKYINEDGTT-TYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
HRDLKP N++ NE T K+ DFG AR+L + G+ Y+ P++ +
Sbjct: 135 HRDLKPQNLLLSTNEATTAPLLKIGDFGFARDLTQGLADTQC-GSPLYMAPEIIQ----- 188
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + A DLWS+G L+ + TG+ PF
Sbjct: 189 ---NQKYDAKADLWSVGAILFQLVTGRPPF 215
>UniRef50_Q5R1T9 Cluster: Cell cycle checkpoint kinase 2; n=1;
Bombyx mori|Rep: Cell cycle checkpoint kinase 2 - Bombyx
mori (Silk moth)
Length = 482
Score = 93.1 bits (221), Expect = 2e-17
Identities = 69/216 (31%), Positives = 108/216 (50%), Gaps = 20/216 (9%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVK-------TFNQLSHMRPHDVQMREFEVLKKVKHEN 69
VLG+GA G V +K A+K T Q++H+ M E ++K ++H
Sbjct: 178 VLGQGACGLVKLVYDKVKCTKHAMKIIKKSRLTNGQINHINKPAKIMNEINIMKALRHPC 237
Query: 70 IVKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
I+ +IEE + R V I++EL GG LF+ + + L E + + +K+
Sbjct: 238 II---SIEEVFDSRDAVYIILELMEGGELFDRITKFSH---LTEPLTRFIFRQMVLAVKY 291
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMY 188
L + HRDLKP N++ +ED T K+TDFG ++ + E+ ++ GT YL P+
Sbjct: 292 LHSQGITHRDLKPENVLLEGDEDETLV-KITDFGLSKFVGEDSFMKTMCGTPLYLAPE-- 348
Query: 189 ERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
VLR ++G VD+WS+GV + G LPF
Sbjct: 349 ---VLRANGQNTYGPEVDVWSLGVIFFVCLVGYLPF 381
>UniRef50_Q4Q0M7 Cluster: Protein kinase, putative; n=3;
Leishmania|Rep: Protein kinase, putative - Leishmania
major
Length = 1255
Score = 93.1 bits (221), Expect = 2e-17
Identities = 72/225 (32%), Positives = 109/225 (48%), Gaps = 21/225 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKV-- 65
EN TT +LGKG G VF V+ N+GE A+K ++ M +D + + EV
Sbjct: 67 ENLRLVTTGLLGKGGFGKVFDAVS-NSGEAYALKVSSK--RMSENDWKRLKEEVTLMSHF 123
Query: 66 -KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
+H NIVK A +++ +VME C G SL +++ + L E L + L
Sbjct: 124 SRHPNIVKFYAAGRDEDRA--YVVMERCAGKSLHDVIA----SRSLDVPEILWIGWALVN 177
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184
+ ++ +HRDLKP N++ D + K+TDFG + + E ++ GT Y+
Sbjct: 178 TISYIHSKGCIHRDLKPQNLLF----DSEGSLKITDFGLSSRISEAHPRKTVAGTAMYMA 233
Query: 185 PDM----YERAVLRKPVGK-SFGATVDLWSIGVTLYHVATGQLPF 224
P+M Y+R S+G VD WSIGV LY + T P+
Sbjct: 234 PEMATEVYKRMTKNSDAPSLSYGKEVDTWSIGVVLYVLLTRMNPY 278
>UniRef50_Q17C01 Cluster: Serine/threonine-protein kinase MAK; n=6;
Eukaryota|Rep: Serine/threonine-protein kinase MAK -
Aedes aegypti (Yellowfever mosquito)
Length = 751
Score = 93.1 bits (221), Expect = 2e-17
Identities = 65/227 (28%), Positives = 106/227 (46%), Gaps = 21/227 (9%)
Query: 14 TTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKL 73
T S LG G G V G K+ GE VA+K + + + +RE + LKK+ H N+VKL
Sbjct: 6 TLSQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHANVVKL 65
Query: 74 LAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
+ E + V E +L+ ++ D EN + E L+L+ + G+ + +
Sbjct: 66 KEVIREND--VLYFVFEYMQ-ENLYQLIKDRENHF--PEATIRLILQQILTGLAFMHRHG 120
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVL 193
HRDLKP N++ G K+ DFG ARE++ + T Y P++ +
Sbjct: 121 FFHRDLKPENVLCC----GPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLHST- 175
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPFRP-YGGRRNKETMFYI 239
+G+ +DLW++G + + T FRP + G + +F I
Sbjct: 176 ------RYGSAIDLWAVGCIMAELYT----FRPLFPGSSEVDQLFKI 212
>UniRef50_A7RL88 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 273
Score = 93.1 bits (221), Expect = 2e-17
Identities = 74/224 (33%), Positives = 106/224 (47%), Gaps = 18/224 (8%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTF-----NQLSHMRPHDVQMREFEVL 62
E W +VLGKGA G VF G+ N GE +AVK N + R ++ E +L
Sbjct: 1 EEIEWQKGNVLGKGAFGTVFLGL-VNTGELIAVKQVELHPNNVDAAERQYEKLQEEVGLL 59
Query: 63 KKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHL 122
K +KH+NIV+ + + I ME GGS+ L + E F +
Sbjct: 60 KSLKHKNIVQYIGTCMDDSQCTINIFMEFVPGGSIAQAL---KRFGAFVEPVFRRYTRQI 116
Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEY 182
G+ +L +NN++HRD+K GNIM N KL DFG A+++ VS
Sbjct: 117 LDGVSYLHNNNVIHRDIKGGNIMLMPN----GVIKLIDFGCAKKICMVGAHVSKSNILRS 172
Query: 183 LHPDMYERA--VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ Y A V+R+ G D+WSIG T++ +ATGQ P+
Sbjct: 173 MRGTPYWMAPEVIRE---TGHGRKSDIWSIGCTVFEMATGQPPW 213
>UniRef50_A0DX23 Cluster: Chromosome undetermined scaffold_68, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_68,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 593
Score = 93.1 bits (221), Expect = 2e-17
Identities = 69/220 (31%), Positives = 116/220 (52%), Gaps = 25/220 (11%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKV 65
GSENY + +G+GA V + VN+ +A K + S H +Q E + ++
Sbjct: 29 GSENY--QIKNPIGRGAGSFVCKIVNRLTKVEMAAKIIQKTSS-NSHKIQ-NEVVIHSEL 84
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
H+NIV L+ + E+ + ++MELC ++ ++ + E + + L G
Sbjct: 85 HHKNIVNLIDVFEDADN--SYLIMELCDQ-DIYQLIKKGQ----FNEQQIRFYGKQLAEG 137
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLH 184
+++L +N++HRD+K GNI+ I D K+ DFG A +L +EE+ +L GT Y+
Sbjct: 138 LQYLHSHNIIHRDIKLGNIL--IQND---ILKIADFGLAVKLTDDEEERNTLCGTPNYIS 192
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ ++P GK VDLWS+G L+ +ATG+ PF
Sbjct: 193 PEILN----QQPYGKK----VDLWSMGCCLFAMATGRGPF 224
>UniRef50_A0C3X2 Cluster: Chromosome undetermined scaffold_148,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_148,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 827
Score = 93.1 bits (221), Expect = 2e-17
Identities = 68/221 (30%), Positives = 112/221 (50%), Gaps = 18/221 (8%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPH--DVQMREFEVLKK 64
+E ++ +LG+G+ G + V + + V + L+ M P D +RE ++L+
Sbjct: 5 AEYELYKRLKLLGEGSFGKAYL-VECLQDKSLWVTKYMDLAAMTPQEKDETLRESKILEF 63
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
+ H NIVK + + ++ R IVME GG L + + + Y E + L L
Sbjct: 64 LSHPNIVKFREVYKTKKAR-LCIVMEYADGGDLAQKIKEAKGKY-FPETQILDWFTQLCL 121
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEE-EQFVSLYGTEEYL 183
+KH+ D ++HRDLK NI ++ ++G KL DFG A+ L++ E+ ++ GT Y+
Sbjct: 122 AIKHVHDRKIIHRDLKGQNI--FLTKEGQI--KLGDFGIAKILKKTVEKAKTMVGTPYYI 177
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ E GK + D+WSIGV LY + Q PF
Sbjct: 178 SPEIIE--------GKPYTFMTDIWSIGVILYELCALQPPF 210
>UniRef50_A0C060 Cluster: Chromosome undetermined scaffold_14, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_14,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 562
Score = 93.1 bits (221), Expect = 2e-17
Identities = 63/216 (29%), Positives = 110/216 (50%), Gaps = 20/216 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G+G+ G V++G NG+ VAVK H + + E +L+K+ H NI++LL +
Sbjct: 17 IGEGSFGQVYKG--NFNGQEVAVK------HQIIQNSFLSEISILEKIDHPNIIRLL--K 66
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E + G +VME C+GG+L + + L E E + ++ L + +++L ++HR
Sbjct: 67 EYKFGNMSYLVMEYCSGGTLKDYIQKK-----LTEDEIIGIMRSLLSAVEYLHGQGIIHR 121
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP NI+ N++ ++ KL DFG + + E Q+ + M +L
Sbjct: 122 DIKPDNIL-IKNKNDLSSIKLADFGLSFQYDAEIQYYQTVSHQCGTFIFMAPEQIL---- 176
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNK 233
S+ TVD WS G+ LY + + P+ P +N+
Sbjct: 177 NMSYNKTVDTWSCGIVLYMLLQKKHPYYPKFSTKNQ 212
>UniRef50_A5DKU9 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 1477
Score = 93.1 bits (221), Expect = 2e-17
Identities = 61/223 (27%), Positives = 119/223 (53%), Gaps = 17/223 (7%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVK--TFNQL-SHMRPHDVQMREFEVLKK 64
E + W ++G+G+ G+V+ +N GE +AVK +++ +++ + +E E +K
Sbjct: 1177 EEFAWIKGELIGRGSFGSVYLALNVTTGEMLAVKQVVLSKIATNLDGINALHKEVETMKD 1236
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124
+ HENIV+ L E++GR + +E GGS+ + + + G +E + +
Sbjct: 1237 LDHENIVQYLGF--ERQGRIYSLFLEYVGGGSIASCM---KFYGGFEEPLIRFICRQVLR 1291
Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFG---AARELQEEEQFVSLYGTEE 181
G+++L N ++HRDLK N++ I DGT K++DFG ++++ +S+ G+
Sbjct: 1292 GLEYLHSNGILHRDLKADNLLLEI--DGTC--KISDFGISKRSKDIYTNNADMSMQGSVF 1347
Query: 182 YLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ P++ + V K K + A VD+WS+G + + G P+
Sbjct: 1348 WMAPEVIDSIVEDKK--KGYSAKVDVWSLGCVVLEMFAGHRPW 1388
>UniRef50_Q6C3D7 Cluster: Serine/threonine-protein kinase STE20; n=1;
Yarrowia lipolytica|Rep: Serine/threonine-protein kinase
STE20 - Yarrowia lipolytica (Candida lipolytica)
Length = 1125
Score = 93.1 bits (221), Expect = 2e-17
Identities = 61/209 (29%), Positives = 104/209 (49%), Gaps = 22/209 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G+GA+G VF + VA+K N L H ++ + E V+K KH+NIV I+
Sbjct: 850 IGQGASGGVFTAYEVGSNLSVAIKQMN-LEHQPKKELIINEILVMKDSKHKNIVNF--ID 906
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQ-EYEFLLVLEHLTAGMKHLRDNNLVH 136
G +VME GGSL +++ TY + E + V G++HL ++H
Sbjct: 907 SYLHGGDLWVVMEYMEGGSLTDVV-----TYNMMTESQIGAVCRETLLGLQHLHSKGVIH 961
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEE-QFVSLYGTEEYLHPDMYERAVLRK 195
RD+K N++ + + KLTDFG ++ E + ++ GT ++ P++ R
Sbjct: 962 RDIKSDNVLLSMRGE----IKLTDFGFCAQINESNLKRTTMVGTPYWMAPEVVSR----- 1012
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K +G+ VD+WS+G+ + G+ P+
Sbjct: 1013 ---KEYGSKVDIWSLGIMSIEMIEGEPPY 1038
>UniRef50_UPI0000D5765F Cluster: PREDICTED: similar to CG14895-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG14895-PA, isoform A - Tribolium castaneum
Length = 508
Score = 92.7 bits (220), Expect = 2e-17
Identities = 55/207 (26%), Positives = 104/207 (50%), Gaps = 18/207 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG GA G V+ + G+PVA+K + R ++ + E ++K +H+N+V L
Sbjct: 222 LGTGAMGIVYAATDLQTGQPVAIKDIDMTKQQR-KELLLSEIAIMKNFQHKNLVNFLDAF 280
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+G +VMEL GG L +++ + ++E+ V + + +L +HR
Sbjct: 281 VMYDGH-LWVVMELLDGGPLTDVVTETV----MKEHHIAAVCHEVLQAIDYLHSRGTIHR 335
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+K N++ ++ DG+ K+TDFG + EQ ++ GT ++ P++ R
Sbjct: 336 DIKSDNVL--LSMDGSV--KVTDFGFCASVVGNEQRETMVGTPYWMAPEVVTR------- 384
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPF 224
+ +G VD+WS+G+ + + G+ P+
Sbjct: 385 -QKYGKKVDIWSLGIMIVEMLDGEPPY 410
>UniRef50_UPI0000ECD6BF Cluster: Serine/threonine-protein kinase
Nek5 (EC 2.7.11.1) (NimA-related protein kinase 5).;
n=1; Gallus gallus|Rep: Serine/threonine-protein kinase
Nek5 (EC 2.7.11.1) (NimA-related protein kinase 5). -
Gallus gallus
Length = 633
Score = 92.7 bits (220), Expect = 2e-17
Identities = 61/209 (29%), Positives = 101/209 (48%), Gaps = 18/209 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G+G+ G +F K + E +K ++ + + +E +L K+KH NIV A
Sbjct: 10 IGEGSFGKIFLAKAKVDNEQCVIK---EIDLTKEKEASQKEVILLAKMKHANIVTFYA-- 64
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
QE IVME C GG L ++ +E + L + G+KH+ D ++HR
Sbjct: 65 SLQEENKLYIVMEYCDGGDLMKRINMQHGVL-FEEDQILSWFVQIALGLKHIHDRKILHR 123
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAVLRKP 196
D+K NI +++ +G KL DFG AR+L + +F + GT YL P++ E
Sbjct: 124 DIKSQNI--FLSSNGKVA-KLGDFGIARQLNDTTEFAYTCVGTPYYLSPEICE------- 173
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+ + D+WS+G LY + + P +
Sbjct: 174 -NRPYNNKTDIWSLGCVLYELCALKHPIK 201
>UniRef50_Q6ZM37 Cluster: Novel protein; n=2; Danio rerio|Rep: Novel
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 690
Score = 92.7 bits (220), Expect = 2e-17
Identities = 65/227 (28%), Positives = 109/227 (48%), Gaps = 18/227 (7%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHEN 69
Y + VLG G G V + ++G +A K ++ M+ D E V+ ++ H N
Sbjct: 402 YAVNPVEVLGGGRFGQVHKCAELSSGLTLAAKII-KVRGMKERDEVKNEIGVMNQLNHVN 460
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
+++L E + ++ME GG LF + D +Y L E + ++ + G+++L
Sbjct: 461 LIQLYDAFESRTNL--TLIMEYVEGGELFERIID--ESYQLTELDAIVFTRQICEGVQYL 516
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189
++H DLKP NI+ +N G K+ DFG AR+ + E+ +GT E+L P++
Sbjct: 517 HQQYILHLDLKPENIL-CVNSTG-NQIKIIDFGLARKYRPREKLKVNFGTPEFLAPEVVN 574
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETM 236
+ P D+WS+GV Y + +G PF G + ETM
Sbjct: 575 YDFVSFP--------TDMWSVGVITYMLLSGLSPFM---GDNDAETM 610
>UniRef50_Q1LVF9 Cluster: Novel kinase domain containing protein;
n=6; Danio rerio|Rep: Novel kinase domain containing
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 640
Score = 92.7 bits (220), Expect = 2e-17
Identities = 66/208 (31%), Positives = 106/208 (50%), Gaps = 16/208 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLG G G V + K++G +A K S + +V E EV+ ++ H N+++L A
Sbjct: 393 VLGGGRFGIVHKCEEKSSGLILAAKIIKARSQ-KEKEVVKCEIEVMNQLNHANLIQLYAA 451
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E + +VM++ GG LF + D EN Y L E + +L + +T G++++ ++H
Sbjct: 452 FESRHEI--TLVMDV-DGGELFERIID-EN-YKLTELDTVLFIRQITEGLQYMHKMYILH 506
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
DLKP NI+ E T K+ DFG AR + E+ +GT E+L P++ + P
Sbjct: 507 LDLKPENILCISRE--TNKVKIIDFGLARRYKPREKLRVNFGTPEFLAPEVINYEFVSFP 564
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
D+WS+GV Y + +G PF
Sbjct: 565 --------TDMWSLGVITYMLLSGLSPF 584
>UniRef50_A7NWI3 Cluster: Chromosome chr5 scaffold_2, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr5 scaffold_2, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 696
Score = 92.7 bits (220), Expect = 2e-17
Identities = 75/255 (29%), Positives = 127/255 (49%), Gaps = 31/255 (12%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHD---VQMREFE----VLKK 64
W ++G GA G V+ G+N ++GE +A+K + ++ + +RE E +LK
Sbjct: 67 WRKGELIGCGAFGRVYMGMNLDSGELLAIKQVSIAANSASKEKTQAHIRELEEEVKLLKN 126
Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLT 123
+ H NIV+ L E E I++E GGS+ ++L +G E + + L
Sbjct: 127 LSHPNIVRYLGTAREDESLN--ILLEFVPGGSISSLL----GKFGSFPESVIRMYTKQLL 180
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV---SLYGTE 180
G+++L N ++HRD+K NI+ D KL DFGA++++ E S+ GT
Sbjct: 181 LGLEYLHKNGIMHRDIKGANIL----VDNKGCIKLADFGASKKVVELATMTGAKSMKGTP 236
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
++ P++ +L+ G SF A D+WS+G T+ +ATG+ P+ + +F+I
Sbjct: 237 YWMAPEV----ILQ--TGHSFSA--DIWSVGCTVIEMATGKPPWSQQ--YQEVAALFHIG 286
Query: 241 TKKASGVISGTQTTE 255
T K+ I T E
Sbjct: 287 TTKSHPPIPEHLTAE 301
>UniRef50_Q54CY9 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 313
Score = 92.7 bits (220), Expect = 2e-17
Identities = 65/208 (31%), Positives = 104/208 (50%), Gaps = 14/208 (6%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+GKGA VF K + A+K ++ S + E E++KKV H NIVK+
Sbjct: 12 IGKGAFSVVFLVTEKKTKKQWAMKIIDKKSSSKA--ALETEIEIMKKVDHPNIVKM---H 66
Query: 78 EEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E E K+ +V+EL TGG LF+ + D ++ E E L+ + L + +L +VH
Sbjct: 67 EYFESTDKIYLVVELVTGGPLFDRIVDKKS---FTEKEAKLITQQLLQSLVYLHSIGIVH 123
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP N++ D T L+DFG ++ + ++ + GT Y+ P++ + P
Sbjct: 124 RDLKPENLLLKTPTD--LTVALSDFGLSKIVGDDVFMKTTCGTPSYVAPEVLNN-ISNSP 180
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ VD+W +GV Y + G PF
Sbjct: 181 T--AYSDAVDMWGVGVITYILLCGFPPF 206
>UniRef50_Q4N365 Cluster: Serine/threonine protein kinase, putative;
n=2; Theileria|Rep: Serine/threonine protein kinase,
putative - Theileria parva
Length = 461
Score = 92.7 bits (220), Expect = 2e-17
Identities = 62/208 (29%), Positives = 102/208 (49%), Gaps = 16/208 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
++ +G+ G V+ V + + A+K N+ + E E+ V+HEN+V+ + I
Sbjct: 87 LINEGSAGKVYLAVGEKH-VLYALKFINKSVDFHSYTKIRDELEISYGVRHENVVETVVI 145
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E + R V+VME C GG L + + E + + + +K+L +NN+ H
Sbjct: 146 METR--RSLVLVMEYCAGGDLITFI---RRNGAITEDKARNAFKMILNAVKYLHNNNIYH 200
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RD+KP N++ + N KL DFGA+ ++ + + GT Y P+ VL
Sbjct: 201 RDIKPENLLIHTN----NVLKLCDFGASIRVRGDVRLYETVGTMSYAAPE-----VLDGT 251
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
G G D+WS+GV LY + GQLP+
Sbjct: 252 CG-YLGEKADVWSLGVVLYAMVFGQLPY 278
>UniRef50_Q24213 Cluster: P21-activated protein kinase 1 Dpak1; n=9;
Eumetazoa|Rep: P21-activated protein kinase 1 Dpak1 -
Drosophila melanogaster (Fruit fly)
Length = 704
Score = 92.7 bits (220), Expect = 2e-17
Identities = 61/220 (27%), Positives = 110/220 (50%), Gaps = 20/220 (9%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKV 65
G N ++ +G+GA+G V+ + + G VA+K N LS ++ + E V+++
Sbjct: 424 GDPNRKYTKMEKIGQGASGTVYSAIESSTGMEVAIKQMN-LSQQPKKELIINEILVMREN 482
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
KH N+V L + +VME GGSL +++ + + E + V +
Sbjct: 483 KHPNVVNYL--DSYLVSEELWVVMEYLPGGSLTDVVTET----CMDEGQIAGVCREVLQA 536
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ-EEEQFVSLYGTEEYLH 184
++ L N ++HRD+K NI+ + DG+ KLTDFG ++ E+ + ++ GT ++
Sbjct: 537 LEFLHANQVIHRDIKSDNIL--LGLDGSV--KLTDFGFCAQISPEQSKRTTMVGTPYWMA 592
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ R K +G VDLWS+G+ + G+ P+
Sbjct: 593 PEVVTR--------KQYGPKVDLWSLGIMAIEMVEGEPPY 624
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.315 0.132 0.379
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 600,722,542
Number of Sequences: 1657284
Number of extensions: 25841155
Number of successful extensions: 96100
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1263
Number of HSP's successfully gapped in prelim test: 8682
Number of HSP's that attempted gapping in prelim test: 80485
Number of HSP's gapped (non-prelim): 12368
length of query: 543
length of database: 575,637,011
effective HSP length: 104
effective length of query: 439
effective length of database: 403,279,475
effective search space: 177039689525
effective search space used: 177039689525
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 75 (34.3 bits)
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