BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000198-TA|BGIBMGA000198-PA|IPR000719|Protein kinase, IPR011009|Protein kinase-like, IPR002290|Serine/threonine protein kinase (543 letters) Database: spombe 5004 sequences; 2,362,478 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |S... 103 5e-23 SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase... 100 1e-21 SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc... 96 1e-20 SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosacch... 87 4e-18 SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosac... 86 1e-17 SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosacc... 83 1e-16 SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|c... 80 7e-16 SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosa... 80 9e-16 SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosac... 77 5e-15 SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizo... 77 6e-15 SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1||... 76 1e-14 SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomy... 75 3e-14 SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Sch... 75 3e-14 SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Pp... 75 3e-14 SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase ki... 75 3e-14 SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|... 73 8e-14 SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizo... 72 2e-13 SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizos... 71 4e-13 SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schiz... 71 4e-13 SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schiz... 71 5e-13 SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces... 70 7e-13 SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosa... 70 1e-12 SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating ... 69 1e-12 SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosac... 69 2e-12 SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccha... 68 3e-12 SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccha... 68 3e-12 SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces po... 67 7e-12 SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2... 66 1e-11 SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosa... 66 1e-11 SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharom... 66 2e-11 SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosa... 65 2e-11 SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Sc... 65 2e-11 SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosac... 65 3e-11 SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|ch... 65 3e-11 SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalyt... 64 4e-11 SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizos... 64 4e-11 SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosacc... 64 5e-11 SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |S... 64 6e-11 SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccha... 63 8e-11 SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosa... 63 1e-10 SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schiz... 63 1e-10 SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizos... 63 1e-10 SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosac... 62 3e-10 SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity prote... 61 3e-10 SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosacchar... 61 4e-10 SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizos... 60 8e-10 SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schiz... 60 1e-09 SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein k... 60 1e-09 SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schi... 59 1e-09 SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Sch... 59 2e-09 SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyc... 58 2e-09 SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyc... 57 5e-09 SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe... 57 7e-09 SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosac... 57 7e-09 SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schi... 56 1e-08 SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase ... 56 1e-08 SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizos... 56 2e-08 SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizos... 55 2e-08 SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosa... 55 2e-08 SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizo... 55 3e-08 SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizo... 55 3e-08 SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase P... 54 4e-08 SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizos... 54 4e-08 SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosacch... 54 4e-08 SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces ... 54 5e-08 SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizo... 54 5e-08 SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosa... 54 5e-08 SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1... 53 1e-07 SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosa... 52 2e-07 SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |S... 52 2e-07 SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Sch... 52 2e-07 SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizo... 51 4e-07 SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizos... 51 5e-07 SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosacchar... 50 6e-07 SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizo... 50 6e-07 SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizos... 50 8e-07 SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schi... 49 2e-06 SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk... 48 3e-06 SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosacchar... 48 3e-06 SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|S... 48 3e-06 SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase S... 48 3e-06 SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosa... 47 6e-06 SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomy... 46 1e-05 SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizos... 46 1e-05 SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Sch... 46 2e-05 SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizo... 45 2e-05 SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizos... 45 2e-05 SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomy... 44 4e-05 SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gc... 44 5e-05 SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosac... 43 1e-04 SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Sch... 42 2e-04 SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces po... 41 4e-04 SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |... 40 0.001 SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizos... 39 0.002 SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizo... 37 0.008 SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosa... 33 0.10 SPBC354.13 |rga6||GTPase activating protein Rga6|Schizosaccharom... 32 0.23 SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces p... 32 0.23 SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosacchar... 31 0.41 SPBC13G1.12 |did2||vacuolar sorting protein Did2|Schizosaccharom... 29 1.2 SPBC713.02c |ubp21|ubpD, ubp15|ubiquitin C-terminal hydrolase Ub... 29 1.2 SPAC3H1.01c |orp3|orc3, SPAP14E8.06c|origin recognition complex ... 29 1.2 SPBC28F2.07 |sfr1|dds20, mug13|Swi five-dependent recombination ... 29 1.6 SPBC336.15 |pic1|SPBC685.01|INCENP-like|Schizosaccharomyces pomb... 29 2.2 SPCC1902.01 |gaf1|SPCC417.01c|transcription factor Gaf1 |Schizos... 29 2.2 SPBC1718.01 |pop1|ste16, SPBC2G2.18|F-box/WD repeat protein Pop1... 28 2.9 SPAC139.05 |||succinate-semialdehyde dehydrogenase |Schizosaccha... 27 5.0 SPAP27G11.07c |||serine/threonine protein kinase |Schizosaccharo... 27 5.0 SPAC26A3.05 |chc1||clathrin heavy chain Chc1 |Schizosaccharomyce... 27 6.7 SPAC30.04c |abc4||glutathione S-conjugate-exporting ATPase Abc4|... 27 6.7 SPBC23G7.08c |rga7||GTPase activating protein Rga7|Schizosacchar... 27 6.7 SPBC365.20c ||SPBC557.06c|nicotinamidase |Schizosaccharomyces po... 27 6.7 SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosa... 27 6.7 SPAC15A10.13 |ppk3||serine/threonine protein kinase Ppk3|Schizos... 27 8.8 SPCC162.08c |nup211||nuclear pore complex associated protein|Sch... 27 8.8 >SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 445 Score = 103 bits (248), Expect = 5e-23 Identities = 64/213 (30%), Positives = 107/213 (50%), Gaps = 8/213 (3%) Query: 14 TTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKL 73 T +LG G ++ ++ N G A K ++ + E +L+K+ H NI+K+ Sbjct: 162 TQRLLGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKRFFEDHEMTILRKLDHPNIIKV 221 Query: 74 LAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133 +E E + I E+ TGG LF+ L + E L ++ + G+K+L + N Sbjct: 222 -NMEYNSETQF-FIFEEMVTGGDLFSYLTKLGT---VPEVTTLFIMFQILQGLKYLHEQN 276 Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE---R 190 ++HRDLK NI+ + D LTDFG AR +Q+ ++ + GT EY P++ R Sbjct: 277 IIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKGKRLSTFVGTPEYTAPEIQRLKGR 336 Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223 + + K +G VDLWS+GV ++ + +G P Sbjct: 337 SQVEKENSSGYGKEVDLWSLGVIMFLLLSGNSP 369 >SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase Cmk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 335 Score = 99.5 bits (237), Expect = 1e-21 Identities = 62/213 (29%), Positives = 108/213 (50%), Gaps = 15/213 (7%) Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76 VLG G V + V+ + A K N+ + D E +LK+V +E+ L + Sbjct: 36 VLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIAILKRVSYEHPNILHLV 95 Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136 + + ++ EL TGG LF+ + + Y E + ++ T+ +K+L DN +VH Sbjct: 96 DFFETVNNLYLITELATGGELFDRICAKGSFY---EADAAALMRTTTSAVKYLHDNGIVH 152 Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQF--VSLYGTEEYLHPDMYERAVLR 194 RDLKP N++ Y ++D + + DFG + ++ + + ++ GT EY+ P+++ R Sbjct: 153 RDLKPENLL-YRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGTPEYMAPEVFRRT--- 208 Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF-RP 226 +G VD+W+IGV Y + +G PF RP Sbjct: 209 -----GYGKPVDMWAIGVITYFLLSGYTPFARP 236 >SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc7|Schizosaccharomyces pombe|chr 2|||Manual Length = 1062 Score = 96.3 bits (229), Expect = 1e-20 Identities = 73/213 (34%), Positives = 111/213 (52%), Gaps = 29/213 (13%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM--REFEVLKKVKHENIVKLLA 75 LGKGA GAV++G+N NGE VAVK +LS M D+ + E ++LK + H NIVK Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKV-KLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRG 73 Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDD----PENTYGLQEYEFLLVLEHLTAGMKHLRD 131 Q I++E C GSL +I + PEN L ++ L G+ +L + Sbjct: 74 --SYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVL-------QGLLYLHN 124 Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERA 191 ++HRD+K NI+ +DG T KL DFG A ++ E S+ G+ ++ P++ E Sbjct: 125 QGVIHRDIKGANIL--TTKDG--TIKLADFGVATKINALEDH-SVVGSPYWMAPEVIEL- 178 Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 VG + + D+WS+G T+ + G P+ Sbjct: 179 -----VGATTAS--DIWSVGCTVIELLDGNPPY 204 >SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosaccharomyces pombe|chr 2|||Manual Length = 652 Score = 87.4 bits (207), Expect = 4e-18 Identities = 59/215 (27%), Positives = 106/215 (49%), Gaps = 19/215 (8%) Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHENI 70 ++ ++G+G+ GAV++G+ E VA+K N D+Q +E VL ++K ++ Sbjct: 10 YTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQ-KEVAVLSELKQSDV 68 Query: 71 VKLLAIEEEQ-EGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129 ++ G I+M+ C GGS+ +++ + E L+L +K + Sbjct: 69 ENIIKYHGSYLVGTNLWIIMDYCHGGSVRTLMEAGP----ISEPCISLILRETLQALKFI 124 Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ-EEEQFVSLYGTEEYLHPDMY 188 ++HRD+K NI+ ++ G KL DFG A EL + ++ GT ++ P+ Sbjct: 125 HHAGIIHRDIKAANIL--VSMSGNV--KLCDFGVAAELNINRRKRITFIGTPYWMAPE-- 178 Query: 189 ERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223 V+R G+ + D+WS+G+T Y +ATG P Sbjct: 179 ---VIRD--GQEYNVMADIWSLGITAYEIATGSPP 208 >SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosaccharomyces pombe|chr 3|||Manual Length = 460 Score = 86.2 bits (204), Expect = 1e-17 Identities = 67/225 (29%), Positives = 105/225 (46%), Gaps = 18/225 (8%) Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQL------SHMRPHDVQMREFE 60 SEN + LG G V V N+G+ A+K N+ S R ++ RE + Sbjct: 162 SENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREID 221 Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120 +LK + H +V+ I E + IVME GG L + L + + E + +L+ Sbjct: 222 ILKSLHHPGVVQCHEIFENDDEL--FIVMEYVEGGDLMDFLIANGS---IDEQDCKPLLK 276 Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GT 179 L + HL + HRD+KP NI+ I D K++DFG A+ + F+ + GT Sbjct: 277 QLLETLLHLHKQGVTHRDIKPENIL--ITND--FHLKISDFGLAKVIHGTGTFLETFCGT 332 Query: 180 EEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 YL P++ + + G + VD+WS+G LY + T +PF Sbjct: 333 MGYLAPEVLKSKNVNLDGG--YDDKVDIWSLGCVLYVMLTASIPF 375 >SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 658 Score = 82.6 bits (195), Expect = 1e-16 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 20/208 (9%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 +G+GA+G V+ VA+K N ++ + + E V+K H+NIV I+ Sbjct: 392 IGQGASGDVYSARQVGTNLSVAIKKMN-INQQPKKEFIVNEILVMKSHHHKNIVNF--ID 448 Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137 +VME GGSL ++ + NT L E + + + G++HL +N +VHR Sbjct: 449 TFFYKSELWMVMEYMRGGSLTEVVTN--NT--LSEGQIAAICKETLEGLQHLHENGIVHR 504 Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEE-EQFVSLYGTEEYLHPDMYERAVLRKP 196 D+K NI+ + D KLTDFG ++ + ++ GT ++ P++ R Sbjct: 505 DIKSDNILLSLQGD----IKLTDFGFCAQIDSNMTKRTTMVGTPYWMAPEVVTR------ 554 Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224 K +G VD+WS+G+ + G+ P+ Sbjct: 555 --KEYGFKVDVWSLGIMAIEMVEGEPPY 580 >SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|chr 1|||Manual Length = 683 Score = 80.2 bits (189), Expect = 7e-16 Identities = 63/222 (28%), Positives = 109/222 (49%), Gaps = 21/222 (9%) Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR---EFEVLKK 64 +N ++ +G+G F+ V N G A K + S ++ +++ E +V + Sbjct: 37 KNIFYTRYDCIGEGGFARCFR-VKDNYGNIYAAKVIAKRS-LQNDKTKLKLFGEIKVHQS 94 Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124 + H NIV + E+ +++ELC SL +L + L E E ++ + Sbjct: 95 MSHPNIVGFIDCFEDSTNI--YLILELCEHKSLMELLRKRKQ---LTEPEVRYLMMQILG 149 Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYL 183 +K++ ++HRDLK GNIM D + K+ DFG AA + +EE+ +++ GT Y+ Sbjct: 150 ALKYMHKKRVIHRDLKLGNIML----DESNNVKIGDFGLAALLMDDEERKMTICGTPNYI 205 Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225 P++ + G SF VDLWS GV +Y + G+ PF+ Sbjct: 206 APEI----LFNSKEGHSF--EVDLWSAGVVMYALLIGKPPFQ 241 >SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosaccharomyces pombe|chr 3|||Manual Length = 355 Score = 79.8 bits (188), Expect = 9e-16 Identities = 64/214 (29%), Positives = 100/214 (46%), Gaps = 20/214 (9%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFN--QLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75 LGKG G V+ K G VA+KT + +L + RE E+ ++H+NI++L Sbjct: 95 LGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKNILRLYG 154 Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135 ++ + +++E G L+ L + +E + + A + +L +++ Sbjct: 155 HFHDE--KRIYLILEFAGRGELYQHLRRAKRFS--EEVASKYIFQMANA-LSYLHKKHVI 209 Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195 HRD+KP NI+ I DG KL+DFG + + +L GT +YL P+M E Sbjct: 210 HRDIKPENILLGI--DGEI--KLSDFGWSVHAPSNRR-TTLCGTLDYLPPEMVE------ 258 Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGG 229 GK VDLWS+GV Y G PF G Sbjct: 259 --GKEHTEKVDLWSLGVLTYEFLVGAPPFEDMSG 290 >SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 436 Score = 77.4 bits (182), Expect = 5e-15 Identities = 63/222 (28%), Positives = 106/222 (47%), Gaps = 20/222 (9%) Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSH-MRPHDVQM--REFEVLKKVKHENIVK 72 +VLG+G+ G V KN G A K + S +R ++ E ++L++V+H I + Sbjct: 95 TVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVRHPFICR 154 Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132 L ++ + ++++ GG LF+ L + L E LT + HL Sbjct: 155 LYYAFQDHDRL--YLILQYAPGGELFSHLAEQRM---LPEDVVAFYTAELTLALIHLHKL 209 Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAV 192 +V+RDLKP N + ++ +G LTDFG ++ + S GTEEY P++ + Sbjct: 210 GIVYRDLKPENCL--LDAEGHIL--LTDFGLSKVAENGADCRSFVGTEEYCAPEI----L 261 Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKE 234 L +P + VD WS+G+ ++ + TG PF +R E Sbjct: 262 LEQP----YDHAVDWWSMGILIFDLLTGSPPFTANNHKRIME 299 >SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1401 Score = 77.0 bits (181), Expect = 6e-15 Identities = 71/230 (30%), Positives = 112/230 (48%), Gaps = 35/230 (15%) Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQM--REFEVLKKVKHE 68 W + G G V+ GVN G+ +AVK Q S V E VL+++ H Sbjct: 1037 WQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEMTVLERLNHP 1096 Query: 69 NIVKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLL--VLEHLTAG 125 N+V +E +E KV I ME C GGSL ++L +G E E +L + L G Sbjct: 1097 NVVTYYGVEVHRE---KVYIFMEFCQGGSLADLL-----AHGRIEDENVLKVYVVQLLEG 1148 Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAA--------RELQEEE---QFV 174 + ++ +++HRD+KP NI+ ++ G Y +DFG+A E++ E+ + Sbjct: 1149 LAYIHSQHILHRDIKPANIL--LDHRGMIKY--SDFGSALYVSPPTDPEVRYEDIQPELQ 1204 Query: 175 SLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 L GT Y+ P++ +L G FGA +D+WS+G + + TG P+ Sbjct: 1205 HLAGTPMYMAPEI----ILGTKKG-DFGA-MDIWSLGCVILEMMTGSTPW 1248 >SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 1116 Score = 76.2 bits (179), Expect = 1e-14 Identities = 66/270 (24%), Positives = 121/270 (44%), Gaps = 32/270 (11%) Query: 2 SFLRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR---- 57 S + + + W ++G G G VF +N N GE +AVK + Q+R Sbjct: 815 SVVSQNATFKWMKGELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIV 874 Query: 58 -----EFEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQ 111 E ++ + H NIV+ L E+ + I +E +GGS+ L YG + Sbjct: 875 DSINAEISMIADLDHLNIVQYLGFEKTETDIS--IFLEYVSGGSIGRCL----RNYGPFE 928 Query: 112 EYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAR---ELQ 168 E V + G+ +L ++HRDLK N++ I+ DG K++DFG ++ + Sbjct: 929 EQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLL--IDFDGVC--KISDFGISKHSDNVY 984 Query: 169 EEEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228 + + +S+ G+ ++ P++ + + A VD+WS+G + + G+ RP+ Sbjct: 985 DNDANLSMQGSIFWMAPEVIHND------HQGYSAKVDVWSLGCVVLEMLAGR---RPWS 1035 Query: 229 GRRNKETMFYITTKKASGVISGTQTTENGP 258 + MF + T+K + I ++ P Sbjct: 1036 TDEAIQAMFKLGTEKKAPPIPSELVSQVSP 1065 >SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 589 Score = 74.9 bits (176), Expect = 3e-14 Identities = 58/213 (27%), Positives = 106/213 (49%), Gaps = 24/213 (11%) Query: 18 LGKGATGAVFQGV---NKNNG--EPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVK 72 LG+GA+G+V+ K G + VA+K+ + R ++ + E V+++ H NIV Sbjct: 315 LGQGASGSVYLAKVVGGKQLGIFDSVAIKSIDLQCQTRK-ELILNEITVMRESIHPNIVT 373 Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132 L +E R +VME GSL +I++ + L E + + G++HL Sbjct: 374 YLDSFLVRE-RHLWVVMEYMNAGSLTDIIEKSK----LTEAQIARICLETCKGIQHLHAR 428 Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYERA 191 N++HRD+K N++ D + K+TDFG AR + V++ GT ++ P++ ++ Sbjct: 429 NIIHRDIKSDNVLL----DNSGNIKITDFGFCARLSNRTNKRVTMVGTPYWMAPEVVKQ- 483 Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 +G VD+WS+G+ + + + P+ Sbjct: 484 -------NEYGTKVDIWSLGIMIIEMIENEPPY 509 >SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Schizosaccharomyces pombe|chr 3|||Manual Length = 830 Score = 74.9 bits (176), Expect = 3e-14 Identities = 65/244 (26%), Positives = 114/244 (46%), Gaps = 45/244 (18%) Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTF--NQLSHMRPHDVQMREFEVLKKVKHENIVKL 73 S +G+G+ V++G + +++K+ +L+ +++ E +LK+++H ++V+L Sbjct: 18 SEIGRGSFAIVYKGKHTETNRVISIKSVLTKKLTKKLLENLES-EISILKEIRHVHVVEL 76 Query: 74 LAIEEEQEGRGKVIVMELCTGGSL------------------FNILDDPENTYGLQEYEF 115 I+ + GR +VME C+ G L NI P GL E Sbjct: 77 --IDCIKAGRFIHLVMEYCSLGDLSYFIRKREKFNSIPSLAWINIDHPPVYKAGLNETLV 134 Query: 116 LLVLEHLTAGMKHLRDNNLVHRDLKPGNIM--------------KYINEDGTTTYKLTDF 161 + L + ++ LR +L+HRD+KP N++ +++ KL DF Sbjct: 135 RHFTQQLASALQFLRSRSLIHRDVKPQNLLLQPPPTAAYLEEHPQFVGSPKLPMLKLADF 194 Query: 162 GAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQ 221 G AR LQ +L G+ Y+ P+ +LR + + A DLWS+G LY +A G+ Sbjct: 195 GFARYLQTSSMAETLCGSPLYMAPE-----ILRY---EKYDAKADLWSVGAVLYEMAVGK 246 Query: 222 LPFR 225 PF+ Sbjct: 247 PPFK 250 >SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Ppk34|Schizosaccharomyces pombe|chr 3|||Manual Length = 354 Score = 74.9 bits (176), Expect = 3e-14 Identities = 50/175 (28%), Positives = 85/175 (48%), Gaps = 12/175 (6%) Query: 51 PHDVQMREFEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGL 110 P+ +E +VLK + HEN+VKL + +V+ C GG L ++ D ++ Sbjct: 114 PYYYIRKELDVLKVLDHENVVKLYQVINSDYKDSLCMVLNYCPGGKLASV--DHGISFDP 171 Query: 111 QEYEFL-LVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQE 169 E L + ++ ++HRD+KP NI+ N + + DFG A L + Sbjct: 172 MPLETCRKSFRQLVLAVNYIHGKGVIHRDIKPDNILFKENNN----LCVIDFGLAEFLPK 227 Query: 170 EEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 + GT ++ P++++ L+K GK +D+WS+GVTLY +A + PF Sbjct: 228 DGFVKPASGTPAFMAPELFDNE-LKKIKGK----PLDIWSMGVTLYVIAFAEFPF 277 >SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase kinase Win1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1436 Score = 74.5 bits (175), Expect = 3e-14 Identities = 76/247 (30%), Positives = 116/247 (46%), Gaps = 52/247 (21%) Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVK--TFNQLSHMRPHDVQMR-EFEVLKKVKHE 68 W ++G G+ G V++ VN + G+ +AVK ++ RP +++ E VL+ H Sbjct: 1120 WQQGGLIGSGSFGTVYRAVNLDTGDLMAVKEVALHKPRISRPMIKRIKGEMLVLELFDHP 1179 Query: 69 NIVKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLL--VLEHLTAG 125 N+V IE +E KV I MELC G SLF L YG E E ++ + L G Sbjct: 1180 NVVSYYGIEVHRE---KVNIFMELCQGSSLFEFL-----RYGRIEDELVIQVYVLQLLEG 1231 Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAR-------------ELQEEEQ 172 + ++ + H+D+KP NI+ D K TDFG+A+ QEEE+ Sbjct: 1232 LAYIHSCGVSHQDVKPENIL----FDHNGIMKFTDFGSAKMSGSASTKIFEQLTQQEEEE 1287 Query: 173 F---------------VSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHV 217 F SL GT Y+ P++ +L P + GA +D+WS+G + + Sbjct: 1288 FEKDSEFLQHLDQNRGYSLTGTPTYMAPEL----ILGNP-SERVGA-MDIWSLGCVIVEM 1341 Query: 218 ATGQLPF 224 ATG P+ Sbjct: 1342 ATGSPPW 1348 >SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|Schizosaccharomyces pombe|chr 3|||Manual Length = 288 Score = 73.3 bits (172), Expect = 8e-14 Identities = 61/223 (27%), Positives = 106/223 (47%), Gaps = 18/223 (8%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 LG+G V++G N+ GE VA+K + +RE ++K+++H NI+ L + Sbjct: 9 LGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHPNIMSLSDVL 68 Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137 + + K++++ L +D N L + + L G+ +N ++HR Sbjct: 69 QTE---NKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHENRVLHR 125 Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQ-EEEQFVSLYGTEEYLHPDMYERAVLRKP 196 DLKP N++ IN G KL DFG AR + F + T Y PD+ +L Sbjct: 126 DLKPQNLL--INSRG--ELKLADFGLARSIGIPVNTFSNEVVTLWYRAPDV----LLGSR 177 Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239 V + ++D+WS+G + +ATG+ P + G N++ + I Sbjct: 178 V---YSTSIDIWSVGCIMAEMATGR-PL--FAGSNNEDQLLKI 214 >SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizosaccharomyces pombe|chr 3|||Manual Length = 569 Score = 72.1 bits (169), Expect = 2e-13 Identities = 62/212 (29%), Positives = 102/212 (48%), Gaps = 22/212 (10%) Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKLL 74 V+GKG+ G V Q ++ A+KT + + +V + E VL +V + IV L Sbjct: 235 VVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQVNNPFIVPL- 293 Query: 75 AIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133 + + GK+ +V+ GG LF+ L E + +F + L ++ L + N Sbjct: 294 --KFSFQSPGKLYLVLAFVNGGELFHHLQR-EGCFDTYRAKFYIA--ELLVALECLHEFN 348 Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAAR-ELQEEEQFVSLYGTEEYLHPDMYERAV 192 +++RDLKP NI+ D T L DFG + + + ++ + GT EYL P++ Sbjct: 349 VIYRDLKPENILL----DYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELL---- 400 Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 +G + VD W++GV LY + TG PF Sbjct: 401 ----LGHGYTKVVDWWTLGVLLYEMITGLPPF 428 >SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizosaccharomyces pombe|chr 2|||Manual Length = 591 Score = 70.9 bits (166), Expect = 4e-13 Identities = 46/159 (28%), Positives = 82/159 (51%), Gaps = 12/159 (7%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ-MREFEVLKKVKHENIVKL--- 73 LG+G G V++ + +G+ A+K + + +RE ++LK +KHENI+ L Sbjct: 42 LGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSIKHENIIPLSDM 101 Query: 74 --LAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131 + +++ RG + ++ L +L++P + E + ++ L AG K+L D Sbjct: 102 TVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKF--TEPQIKCYMKQLFAGTKYLHD 159 Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEE 170 ++HRDLK N++ I+ G K+ DFG AR + EE Sbjct: 160 QLILHRDLKAANLL--IDNHG--ILKIADFGLARVITEE 194 >SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schizosaccharomyces pombe|chr 3|||Manual Length = 576 Score = 70.9 bits (166), Expect = 4e-13 Identities = 58/211 (27%), Positives = 100/211 (47%), Gaps = 23/211 (10%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR---EFEVLKKVKHENIVKLL 74 LG+G+ G V + + VA+K F ++ D+ MR E LK ++H +I+KL Sbjct: 40 LGEGSFGKVKLATHYKTQQKVALK-FISRQLLKKSDMHMRVEREISYLKLLRHPHIIKLY 98 Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134 + V+V+E GG LF+ + + + + E E + + +++ + + Sbjct: 99 DVITTPTDI--VMVIEYA-GGELFDYIVEKKR---MTEDEGRRFFQQIICAIEYCHRHKI 152 Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194 VHRDLKP N++ D K+ DFG + + + + G+ Y P++ Sbjct: 153 VHRDLKPENLLL----DDNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVIN----- 203 Query: 195 KPVGKSF-GATVDLWSIGVTLYHVATGQLPF 224 GK + G VD+WS G+ LY + G+LPF Sbjct: 204 ---GKLYAGPEVDVWSCGIVLYVMLVGRLPF 231 >SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schizosaccharomyces pombe|chr 2|||Manual Length = 398 Score = 70.5 bits (165), Expect = 5e-13 Identities = 61/203 (30%), Positives = 100/203 (49%), Gaps = 18/203 (8%) Query: 20 KGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDV-QMREFEVLKKVKHENIVKLLAIEE 78 +G+ G V++G++K+ VA+K + + +RE E L ++H+NIV+L + Sbjct: 82 EGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHDNIVELEKVVV 141 Query: 79 EQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137 ++ + +VME L +LD+ PE+ + +L L TA M H + +HR Sbjct: 142 GKDLKDVYLVMEFME-HDLKTLLDNMPEDFLQSEVKTLMLQLLAATAFMHH---HWYLHR 197 Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQE-EEQFVSLYGTEEYLHPDMYERAVLRKP 196 DLKP N++ + T KL DFG AR + E + L T Y P++ +L P Sbjct: 198 DLKPSNLLM----NNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPEL----LLGAP 249 Query: 197 VGKSFGATVDLWSIGVTLYHVAT 219 S+G +D+WSIG + T Sbjct: 250 ---SYGKEIDMWSIGCIFAEMIT 269 >SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces pombe|chr 1|||Manual Length = 312 Score = 70.1 bits (164), Expect = 7e-13 Identities = 57/218 (26%), Positives = 104/218 (47%), Gaps = 18/218 (8%) Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKH 67 E + + ++G+G+ G+VF+ + + + VA+K + + + +E L + Sbjct: 2 EKHQYRDLQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDLNS 61 Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127 +I K A +G I ME C GGS ++L T+ E V+ + + Sbjct: 62 VHITKYYA--SFVDGFRLWITMEYCDGGSCLDLLK-LSGTFS--ERVIAEVMRQVLEALV 116 Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQE-EEQFVSLYGTEEYLHPD 186 +L +HRD+K NI+ +DG KL DFG + +L+ ++ GT ++ P+ Sbjct: 117 YLHGQGKMHRDIKAANILTM--KDGLV--KLADFGVSGQLESLRDKNDDFVGTPFWMAPE 172 Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 + K G ++ A D+WS+G+T Y +ATG+ P+ Sbjct: 173 VV------KQTGYNYKA--DIWSLGITAYELATGEPPY 202 >SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosaccharomyces pombe|chr 1|||Manual Length = 650 Score = 69.7 bits (163), Expect = 1e-12 Identities = 71/284 (25%), Positives = 124/284 (43%), Gaps = 17/284 (5%) Query: 11 VWSTTSVLGKGATGAVFQGVNKN-NGEPVAVKTFNQLSHMRPHDVQMREFEVLKKV-KHE 68 V++ +G G G+V+ K + E VA+K+ + ++RE L ++ ++E Sbjct: 35 VYNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENE 94 Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128 NIV + + +Q R IVME +L+ ++ +N L + ++ + G+ H Sbjct: 95 NIVNIFDLYIDQF-RCLHIVMEFLDC-NLYQLISTRKND-PLTLEQVQDIMRQIFKGLNH 151 Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTT-TYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187 + N HRD+KP NI+ N D ++ K+ DFG ARE+ + T Y P++ Sbjct: 152 IHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPPYTEYVSTRWYRAPEL 211 Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGV 247 R + VD+++ G + +AT Q P P G + + ++ + S Sbjct: 212 LLR-------DSYYSFPVDIYAAGCMAFEIATLQ-PIFP--GNDDFDQLYKMCEILGSPD 261 Query: 248 ISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDP 291 T + G W R +L + L K+ PL G L P Sbjct: 262 EQSQNTGDKGGGIWDRAELLANKLGISLPKM-APLDFGDLFSPP 304 >SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating kinase Crk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 335 Score = 69.3 bits (162), Expect = 1e-12 Identities = 51/206 (24%), Positives = 94/206 (45%), Gaps = 17/206 (8%) Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ-MREFEVLKKV 65 S+ + + +G+G VF G K VA+K D+ +RE + L++ Sbjct: 6 SDKWTYVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRES 65 Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125 +H+N+++L+ + + I++E L ++ D + + +V+ L G Sbjct: 66 RHDNVIELVDVFSTKSNLN--IILEFLDS-DLEMLIKDKFIVFQPAHIKSWMVM--LLRG 120 Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185 + H+ ++HRDLKP N++ I+ DG KL DFG +R+ T Y P Sbjct: 121 LHHIHSRFILHRDLKPNNLL--ISSDG--VLKLADFGLSRDFGTPSHMSHQVITRWYRPP 176 Query: 186 DMYERAVLRKPVGKSFGATVDLWSIG 211 +++ +S+G VD+WS+G Sbjct: 177 ELFMGC-------RSYGTGVDMWSVG 195 >SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 68.5 bits (160), Expect = 2e-12 Identities = 60/215 (27%), Positives = 96/215 (44%), Gaps = 22/215 (10%) Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENI 70 VW LG G+T V + G+ A+K + +R + M E +++ ++H NI Sbjct: 11 VWRLGKTLGTGSTSCVRLAKHAKTGDLAAIK----IIPIRYASIGM-EILMMRLLRHPNI 65 Query: 71 VKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHL 129 ++L + + + + +E G LF+ + +G L E E L + + H Sbjct: 66 LRLYDVWTDHQHM--YLALEYVPDGELFHYI----RKHGPLSEREAAHYLSQILDAVAHC 119 Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189 HRDLK NI+ +NE K+ DFG A + + G+ YL P++ Sbjct: 120 HRFRFRHRDLKLENILIKVNEQ---QIKIADFGMATVEPNDSCLENYCGSLHYLAPEI-- 174 Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 V KP GA D+WS GV LY + + +LPF Sbjct: 175 --VSHKPYR---GAPADVWSCGVILYSLLSNKLPF 204 >SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 363 Score = 68.1 bits (159), Expect = 3e-12 Identities = 59/212 (27%), Positives = 91/212 (42%), Gaps = 14/212 (6%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 LG+G +G+V + + A+KT + +RE ++ + IVK Sbjct: 85 LGEGVSGSVRKCRIRGTQMIFAMKTVLAAPNTALQKQLLRELKINRSCTSPYIVKYYGAC 144 Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQ-EYEFLLVLEHLTAGMKHLRDNNLVH 136 I ME C GSL I + G E + + +G+ +L D ++H Sbjct: 145 YNNAECQLNIAMEYCGAGSLDAIYKRVRSQGGRTGERPLGKIAFGVLSGLSYLHDRKIIH 204 Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196 RD+KP NI+ + G KL DFG + EL + GT Y+ P+ Sbjct: 205 RDIKPSNIL--LTSKGQV--KLCDFGVSGELVNSLAG-TFTGTSYYMAPERIS------- 252 Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228 G S+ + D+WS+G+TL VA + PF P G Sbjct: 253 -GGSYTISSDIWSLGLTLMEVALNRFPFPPEG 283 >SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 68.1 bits (159), Expect = 3e-12 Identities = 56/221 (25%), Positives = 100/221 (45%), Gaps = 20/221 (9%) Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEV--LKK 64 SE W LG G + ++ G+ VK S + E E+ L+ Sbjct: 5 SEVGPWELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRL 64 Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTA 124 ++H N+++L+ + QE +V+E GG LF+ + E + L + Sbjct: 65 IEHPNVLQLIDVISAQEQL--FVVVEYMPGGELFDCM---LRKGSFTEQDTAKFLWQILC 119 Query: 125 GMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLH 184 G+++ ++ HRDLKP N+ Y++ G+ K+ +FG A Q + + G+ Y Sbjct: 120 GLEYCHKLHICHRDLKPENL--YLDAHGSI--KIGEFGMASIQQPGKLLQTSCGSPHYAS 175 Query: 185 PDMYERAVLRKPVGKSF-GATVDLWSIGVTLYHVATGQLPF 224 P++ +G+S+ G D+WS G+ + + TG+LPF Sbjct: 176 PEII--------MGRSYDGCASDIWSCGIIFFALLTGKLPF 208 >SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces pombe|chr 1|||Manual Length = 471 Score = 66.9 bits (156), Expect = 7e-12 Identities = 53/208 (25%), Positives = 95/208 (45%), Gaps = 20/208 (9%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRP-HDVQMREFEVLKKVKHENIVKLLAI 76 LG G+ G V++ +G+ +A+K + + + D++ F +L N+++ Sbjct: 15 LGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVF-MLSNCNSSNVIQYYGC 73 Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136 + G I+ME GGS+ +L L E ++L + G+ +L N +H Sbjct: 74 FVD--GYTLWILMEHMDGGSVSGLLKMGR----LNEQVISIILREVLYGLNYLHGQNKIH 127 Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQE-EEQFVSLYGTEEYLHPDMYERAVLRK 195 RD+K NI+ T KL DFG A +L + + GT ++ P++ ++ Sbjct: 128 RDIKAANILL---SSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQT---- 180 Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLP 223 S+G D+WS+G+T +A G P Sbjct: 181 ----SYGLAADIWSLGITAIEMANGIPP 204 >SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2|Schizosaccharomyces pombe|chr 2|||Manual Length = 659 Score = 66.1 bits (154), Expect = 1e-11 Identities = 55/223 (24%), Positives = 103/223 (46%), Gaps = 23/223 (10%) Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVK--TFNQLS-----HMRPHDVQMREFEVLKK 64 W +++G G+ G V+ G+N ++GE +AVK + +S H + D E +L++ Sbjct: 394 WIRGALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQE 453 Query: 65 VKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLT 123 + HE+IV+ L + I +E GGS+ +L YG +E ++ Sbjct: 454 LSHEHIVQYLGSNLNSDHLN--IFLEYVPGGSVAGLL----TMYGSFEETLVKNFIKQTL 507 Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183 G+++L +VHRD+K NI+ D K++DFG +++L+ G Sbjct: 508 KGLEYLHSRGIVHRDIKGANIL----VDNKGKIKISDFGISKKLELNSTSTKTGGARPSF 563 Query: 184 HPDMYERA--VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 + A V+++ + D+WS+G + + T + P+ Sbjct: 564 QGSSFWMAPEVVKQTMHTE---KTDIWSLGCLVIEMLTSKHPY 603 >SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosaccharomyces pombe|chr 3|||Manual Length = 877 Score = 66.1 bits (154), Expect = 1e-11 Identities = 56/206 (27%), Positives = 99/206 (48%), Gaps = 18/206 (8%) Query: 16 SVLGKGATGAVFQGVNK-NNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVK-HENIVK 72 ++LG G VFQ + AVK + S + + ++E + + +K H++IV+ Sbjct: 570 TLLGSGEFSEVFQVEDPVEKTLKYAVKKLKVKFSGPKERNRLLQEVSIQRALKGHDHIVE 629 Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132 L+ + + G + +ELC GSL L++ L E+ +L + G++ + Sbjct: 630 LM--DSWEHGGFLYMQVELCENGSLDRFLEEQGQLSRLDEFRVWKILVEVALGLQFIHHK 687 Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAV 192 N VH DLKP N+M I +G T K+ DFG A + + + G EY+ P++ + Sbjct: 688 NYVHLDLKPANVM--ITFEG--TLKIGDFGMA-SVWPVPRGMEREGDCEYIAPEVLANHL 742 Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVA 218 KP D++S+G+T++ A Sbjct: 743 YDKP--------ADIFSLGITVFEAA 760 >SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharomyces pombe|chr 2|||Manual Length = 1016 Score = 65.7 bits (153), Expect = 2e-11 Identities = 55/216 (25%), Positives = 101/216 (46%), Gaps = 24/216 (11%) Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM-----REFEVLKKVKHENI 70 SVLGKG G V K+ + A+K + + +V+ R F V + +H + Sbjct: 687 SVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVANRERHPFL 746 Query: 71 VKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLR 130 V L + + + VM+ +GG L +L + + + +F + +K+ Sbjct: 747 VNLHSCFQTETRI--YFVMDFVSGGDL--MLHIQQEQFSRRRAQFYAA--EVCLALKYFH 800 Query: 131 DNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYE 189 DN +++RDLK NI+ ++ DG K+ D+G +E + + + GT E++ P++ Sbjct: 801 DNGIIYRDLKLDNIL--LSPDGHV--KVADYGLCKEDMWHDNTTATFCGTPEFMAPEIL- 855 Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225 + + + +VD W+ GV +Y + GQ PFR Sbjct: 856 -------LEQQYTRSVDWWAFGVLIYQMLLGQSPFR 884 >SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 652 Score = 65.3 bits (152), Expect = 2e-11 Identities = 47/175 (26%), Positives = 84/175 (48%), Gaps = 17/175 (9%) Query: 57 REFEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSL-FNILDDPENTYGLQEYEF 115 RE +LKK H N+V+L + ++ +V+E +GG + + D P L E Sbjct: 189 REIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPV----LSISEA 244 Query: 116 LLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFG----AARELQEEE 171 + G+++L ++HRD+KP N++ + + K++DFG A L E+ Sbjct: 245 RQYFRDVVLGLEYLHYQGIIHRDIKPANLLL----NSSNCVKISDFGVSYIANAGLNEDN 300 Query: 172 --QFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 + GT + P++ L +P K +D+W++GVTL+ + G+ PF Sbjct: 301 DVELAKTVGTPAFFAPELC-WTDLDRPRPK-ISEAIDVWALGVTLFCLLFGRCPF 353 >SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 474 Score = 65.3 bits (152), Expect = 2e-11 Identities = 43/165 (26%), Positives = 82/165 (49%), Gaps = 10/165 (6%) Query: 62 LKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLL-VLE 120 L + +H NI+ +E ++ +V+E C G L+ + + + + E + + Sbjct: 62 LSRSRHRNIIHF--VESFEDNVYYYVVLEYCPLGDLYECILNNDFPNAKNQPEMIKNIFL 119 Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGT-TTYKLTDFGAARELQEEEQFVSLYGT 179 + G+ HL + + HRDLKP N + ++EDG+ K++DFG A + F + G+ Sbjct: 120 QIIDGVAHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFGLACRDKISYDFGT--GS 177 Query: 180 EEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 + Y+ P+ +E G S A D+W++G+ L ++ + PF Sbjct: 178 DRYMAPEQFEEV---DGAGYSPRA-ADIWALGICLLNLIFARNPF 218 >SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosaccharomyces pombe|chr 2|||Manual Length = 559 Score = 64.9 bits (151), Expect = 3e-11 Identities = 60/210 (28%), Positives = 102/210 (48%), Gaps = 20/210 (9%) Query: 18 LGKGATGAVFQGVNKN-NG--EPVAVKTFNQLSHMRP-HDV-QMREFEVLKKV-KHENIV 71 LG G+ G V+ K NG E VAVK S +P H++ ++RE L+K+ KH ++ Sbjct: 27 LGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRKISKHPCLI 86 Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131 LL + R +VME +LF + + +E F ++L+ + +G++H+ Sbjct: 87 DLLETFMDPY-RNIFLVMEFMDC-NLFQLFKRRQGRLFTKETAFNILLQ-IISGIEHIHK 143 Query: 132 NNLVHRDLKPGNIM-KYINE---DGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187 + +HRD+KP NI+ K I+ + KL DFG AR + T Y P++ Sbjct: 144 HGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLARPSVSSDPLTEYVSTRWYRAPEL 203 Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHV 217 R+ S+ +VDL++ G ++ + Sbjct: 204 LLRS-------GSYNHSVDLYAFGCIVFEI 226 >SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 372 Score = 64.9 bits (151), Expect = 3e-11 Identities = 56/202 (27%), Positives = 88/202 (43%), Gaps = 15/202 (7%) Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75 +++G+GA G V ++K +G VAVK + +H +RE ++L+ +HENI+ +L Sbjct: 43 NLIGQGAYGVVCAALHKPSGLKVAVKKIHPFNHPVFCLRTLREIKLLRHFRHENIISILD 102 Query: 76 I---EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132 I QE IV EL I P + Q + + + +K + Sbjct: 103 ILPPPSYQELEDVYIVQELMETDLYRVIRSQPLSDDHCQYFTY-----QILRALKAMHSA 157 Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAV 192 +VHRDLKP N++ N D K+ DFG AR + EY+ Y Sbjct: 158 GVVHRDLKPSNLLLNANCD----LKVADFGLARSTTAQGGNPGF--MTEYVATRWYRAPE 211 Query: 193 LRKPVGKSFGATVDLWSIGVTL 214 + + + +DLWS G L Sbjct: 212 IMLSF-REYSKAIDLWSTGCIL 232 >SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalytic subunit Pka1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 512 Score = 64.5 bits (150), Expect = 4e-11 Identities = 59/213 (27%), Positives = 97/213 (45%), Gaps = 28/213 (13%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQ--LSHMRPHDVQMREFEVLKKVKHENIVKLLA 75 LG G+ G V + +N A+K + + M+ + E +L +V+H I L Sbjct: 207 LGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILSRVQHPFITILWG 266 Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDD----PENTYGLQEYEFLLVLEHLTAGMKHLRD 131 Q+ + +VM+ GG LF++L PE E +L L++L Sbjct: 267 TF--QDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYL-------HH 317 Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERA 191 N +V+RDLKP N++ D K+ DFG A+ + +L GT +YL P++ Sbjct: 318 NQIVYRDLKPENLLL----DRFGHLKIVDFGFAKRV-STSNCCTLCGTPDYLAPEI---- 368 Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 + KP K+ D WS+G+ ++ + G PF Sbjct: 369 ISLKPYNKA----ADWWSLGILIFEMLAGYPPF 397 >SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizosaccharomyces pombe|chr 2|||Manual Length = 953 Score = 64.5 bits (150), Expect = 4e-11 Identities = 56/188 (29%), Positives = 89/188 (47%), Gaps = 27/188 (14%) Query: 58 EFEVLKKVK-HENIVKLL---AIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQE 112 E E +K++K H +IV + A+ + E R +V ++ME C GG L + ++ + L E Sbjct: 101 EIETMKRLKGHRHIVNYIDSSALYSKSENRYEVYLLMEFCAGGGLIDFMNT-RLQHRLTE 159 Query: 113 YEFLLVLEHL--TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE---- 166 E L +L + H D L+HRDLK N++ +YKL DFG+A E Sbjct: 160 GEILKILADVCDAVAAMHYLDPPLIHRDLKIENVLLV----APNSYKLCDFGSACEPLAP 215 Query: 167 ------LQEEEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATG 220 + EQ ++ Y T +Y P+M + + R+ + D+W+IGV Y + Sbjct: 216 ATTPDTIMFLEQNIAAYTTPQYRAPEMID--INRR---QGIDEKSDIWAIGVLAYKLCYY 270 Query: 221 QLPFRPYG 228 PF G Sbjct: 271 TTPFEQVG 278 >SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosaccharomyces pombe|chr 1|||Manual Length = 636 Score = 64.1 bits (149), Expect = 5e-11 Identities = 62/219 (28%), Positives = 102/219 (46%), Gaps = 30/219 (13%) Query: 17 VLGKGATGAV---FQGVNKNNGEPV--AVKTFNQLSHMRPHDVQMR---EFEVLKKVKHE 68 V+G+GA G V + +N+G AVK F + R EF + ++H Sbjct: 356 VIGRGAFGVVRIAHKVDPQNSGSETLYAVKEFRRKPAESQKKYTKRLTSEFCISSSLRHP 415 Query: 69 NIVKLLAIEEEQEGRGKVI-VMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127 N++ L + Q+G+G VMELC+GG L+ ++ L+ E + L G+ Sbjct: 416 NVIHTLDLI--QDGKGDYCEVMELCSGGDLYTLIMAAGR---LEPMEADCFFKQLMRGVD 470 Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFG---AARELQEEEQFVS--LYGTEEY 182 +L D + HRDLKP N++ + + + K+TDFG R E+E ++ L G+ Y Sbjct: 471 YLHDMGVAHRDLKPENLLLTV----SGSLKITDFGNGECFRMAWEKEAHMTCGLCGSAPY 526 Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQ 221 + P+ Y + VD+W+ GV + TG+ Sbjct: 527 IAPEEYTESEFDP-------RAVDVWACGVIYMAMRTGR 558 >SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |Schizosaccharomyces pombe|chr 1|||Manual Length = 672 Score = 63.7 bits (148), Expect = 6e-11 Identities = 56/211 (26%), Positives = 95/211 (45%), Gaps = 22/211 (10%) Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75 SV+G+G+ G V+ + V +K+ S + + RE +++ H NI +L Sbjct: 35 SVVGEGSFGKVYLAAHLLTNTKVVLKS----SCRKQAIILAREIHHHRRLLHPNITRLYE 90 Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135 + ++ + ME C G L++ + + L E ++ L +++L V Sbjct: 91 VVCTEDRI--YLAMEYCPNGELYDWVAREKR---LDEKTTCRIMWQLCCAIQYLHRQGCV 145 Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ-EEEQFVSLY-GTEEYLHPDMYERAVL 193 HRDLK NI D KL DFG +R+ F++ GT Y P++ + Sbjct: 146 HRDLKLENIFL----DKAYNVKLGDFGFSRDSDCSRRTFMNTRCGTVAYCAPELVQGH-- 199 Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 K G VD+WS+G+ +Y + G+LPF Sbjct: 200 -----KYIGECVDIWSLGIIMYALLIGRLPF 225 >SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccharomyces pombe|chr 2|||Manual Length = 605 Score = 63.3 bits (147), Expect = 8e-11 Identities = 57/213 (26%), Positives = 98/213 (46%), Gaps = 19/213 (8%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 LGKG G V++ +++ G +A+K + + E ++L K IV Sbjct: 326 LGKGNYGVVYKALHQPTGVTMALKEIRLSLEEATFNQIIMELDILHKAVSPYIVDFYGAF 385 Query: 78 EEQEGRGKVIV-MELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD-NNLV 135 + G V + ME GS+ + G+ V++ G+K L++ +N++ Sbjct: 386 FVE---GSVFICMEYMDAGSMDKLYAGGIKDEGVLARTAYAVVQ----GLKTLKEEHNII 438 Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195 HRD+KP N++ +N +G KL DFG + L ++ G + Y+ P ER + Sbjct: 439 HRDVKPTNVL--VNSNGQV--KLCDFGVSGNLVASISKTNI-GCQSYMAP---ERIRVGG 490 Query: 196 PVGKSFGATV--DLWSIGVTLYHVATGQLPFRP 226 P TV D+WS+G+T+ +A G P+ P Sbjct: 491 PTNGVLTYTVQADVWSLGLTILEMALGAYPYPP 523 >SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosaccharomyces pombe|chr 1|||Manual Length = 696 Score = 62.9 bits (146), Expect = 1e-10 Identities = 58/213 (27%), Positives = 103/213 (48%), Gaps = 20/213 (9%) Query: 17 VLGKGATGAVFQGVNKNNGEPV-AVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKL 73 ++GKG G V+ V KN+ + A+K ++ +R +V + E +L + + + Sbjct: 307 LIGKGTFGQVYL-VRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRTSLDESPFI 365 Query: 74 LAIEEE-QEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132 + ++ Q ++ + +GG LF L E + Q +F + L ++HL + Sbjct: 366 VGLKFSFQTASDLYLITDYMSGGELFWHLQH-EGRFPEQRAKFYIA--ELVLALEHLHKH 422 Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAR-ELQEEEQFVSLYGTEEYLHPDMYERA 191 ++++RDLKP NI+ ++ DG L DFG ++ L + GT EYL P+ Sbjct: 423 DIIYRDLKPENIL--LDADGHIA--LCDFGLSKANLSANATTNTFCGTTEYLAPE----- 473 Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 VL + K + VD WS+GV ++ + G PF Sbjct: 474 VLLE--DKGYTKQVDFWSLGVLVFEMCCGWSPF 504 >SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schizosaccharomyces pombe|chr 2|||Manual Length = 526 Score = 62.9 bits (146), Expect = 1e-10 Identities = 55/230 (23%), Positives = 98/230 (42%), Gaps = 27/230 (11%) Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKLL 74 +LG+G G V+ K+N A+K N+ ++ H V + E E+L K KH IV L Sbjct: 160 LLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLAEQEILTKSKHPFIVTLY 219 Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133 + ++ + ME C GG F L P++ L E + +TA +++L Sbjct: 220 HSFQSRDYL--YLCMEYCAGGEFFRALHSLPKHI--LPEKDACFYAAEVTAALEYLHLMG 275 Query: 134 LVHRDLKPGNIMKY------------------INEDGTTTYKLTDFGAARELQEEEQFVS 175 ++RDLKP NI+ + + K + F + + + S Sbjct: 276 FIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFSQEKPALDTNSYFS 335 Query: 176 LYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225 + T ++ + Y + + G + VD W++G+ +Y + G PF+ Sbjct: 336 NFRTNSFVGTEEYIAPEVIRSCGHT--VAVDWWTLGIFIYEILYGTTPFK 383 >SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizosaccharomyces pombe|chr 2|||Manual Length = 461 Score = 62.9 bits (146), Expect = 1e-10 Identities = 53/181 (29%), Positives = 83/181 (45%), Gaps = 26/181 (14%) Query: 56 MREFEVLKKVKHENIVKLLA-----IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGL 110 +RE+ + K+ H NI+K++ + G +V E C G LF ++ E L Sbjct: 173 LREWSIQPKLDHPNILKVICPCVTLTSVFNKSAGFCLVQEYCPQGDLFKQIE--EKVLTL 230 Query: 111 QEYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL--- 167 ++ L+ + + +L+ + HRDLKP NI+ I DG KLTDFG + + Sbjct: 231 EDK--CCYLKQILQAVAYLQSQRIAHRDLKPENIL--IGRDG--LLKLTDFGTSEIVGNP 284 Query: 168 --QEEEQFVS-LYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 E +FVS G+ YL P+ + + G D WS G+ L + TG PF Sbjct: 285 GDNESIRFVSGAVGSLAYLAPEAFHE-------NEYCGLLADRWSCGILLKVLFTGYFPF 337 Query: 225 R 225 + Sbjct: 338 K 338 >SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosaccharomyces pombe|chr 2|||Manual Length = 365 Score = 61.7 bits (143), Expect = 3e-10 Identities = 52/228 (22%), Positives = 100/228 (43%), Gaps = 8/228 (3%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 +G G+ G ++ G N +GE VA+K + + + + R + +L V+ +E Sbjct: 17 IGSGSFGDIYLGTNVVSGEEVAIKLESTRAKHPQLEYEYRVYRILSGGVGIPFVRWFGVE 76 Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137 + +VM+L G SL ++ + + L+ LL+ + L + ++ + + +HR Sbjct: 77 CDYNA----MVMDLL-GPSLEDLFNFCNRKFSLKTV--LLLADQLISRIEFIHSKSFLHR 129 Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197 D+KP N + I + G + DFG A++ ++ + + + E A + + Sbjct: 130 DIKPDNFLMGIGKRGNQV-NIIDFGLAKKYRDHKTHLHIPYRENKNLTGTARYASINTHL 188 Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKAS 245 G DL S+G L + G LP++ K+ I KK S Sbjct: 189 GIEQSRRDDLESLGYVLVYFCRGSLPWQGLKATTKKQKYEKIMEKKIS 236 >SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity protein kinase Mph1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 678 Score = 61.3 bits (142), Expect = 3e-10 Identities = 59/217 (27%), Positives = 97/217 (44%), Gaps = 17/217 (7%) Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVK-HENIVKLL 74 V+GKG + V++ + +N A+K N ++ E +L+K+ ++ I+KL Sbjct: 321 VVGKGGSSMVYRIFSPDNSRLYALKEVNFINADQTTIQGYKNEIALLRKLSGNDRIIKLY 380 Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFL-LVLEHLTAGMKHLRDNN 133 A E +VME C L N+L +N F+ + E + ++ + D N Sbjct: 381 AAEVNDTLGQLNMVME-CGETDLANLL--MKNMKKPINLNFIRMYWEQMLEAVQVVHDQN 437 Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV---SLYGTEEYLHPDMYER 190 +VH DLKP N ++ +G KL DFG A+ + + + S GT Y+ P+ Sbjct: 438 IVHSDLKPAN---FLLVEG--NLKLIDFGIAKAIGNDTTNIHRDSHIGTINYMAPEALTD 492 Query: 191 AVLRKPVG---KSFGATVDLWSIGVTLYHVATGQLPF 224 G G D+WS+G LY + G+ PF Sbjct: 493 MNAHTNSGVKLVKLGRPSDVWSLGCILYQMVYGRAPF 529 >SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosaccharomyces pombe|chr 1|||Manual Length = 988 Score = 60.9 bits (141), Expect = 4e-10 Identities = 55/216 (25%), Positives = 97/216 (44%), Gaps = 24/216 (11%) Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMRE-----FEVLKKVKHENI 70 +VLGKG G V K N + A+K + + ++ +++ + FEV K KH + Sbjct: 668 AVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKHVFEVANKEKHPFL 727 Query: 71 VKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLR 130 + L A Q VME GG L ++ + ++ F + +K+ Sbjct: 728 LNLFA--SFQTSTRVYFVMEYILGGDL--MVHIQRQQFSVKRARFYGA--EVCLALKYFH 781 Query: 131 DNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYE 189 +N + +RDLK NI+ + DG ++ D+G +E S + GT E++ P++ Sbjct: 782 ENGIAYRDLKLDNIL--LCPDGHI--RIADYGLCKENMLLGNTTSTFCGTPEFMAPEIL- 836 Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225 + + + VD W+ GV +Y + GQ PF+ Sbjct: 837 -------LEQQYSKDVDWWAFGVLMYQMLLGQSPFK 865 >SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizosaccharomyces pombe|chr 2|||Manual Length = 872 Score = 60.1 bits (139), Expect = 8e-10 Identities = 44/155 (28%), Positives = 73/155 (47%), Gaps = 23/155 (14%) Query: 86 VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK--HLRDNNLVHRDLKPGN 143 +++ME C GG L + ++ T L E+E L ++ + G+ H L+HRDLK N Sbjct: 110 LLLMEYCAGGGLIDFMNQRLQTR-LSEHEVLKIISDIVQGVASLHYLRPPLIHRDLKVEN 168 Query: 144 IMKYINEDGTTTYKLTDFGA----------ARELQEEEQFVSLYGTEEYLHPDMYERAVL 193 ++ N T+KL DFG+ + E+Q E+ ++ + T +Y P+M + Sbjct: 169 VLLSFN-----TFKLCDFGSVTEPMHAAENSSEIQALEKSINTFTTYQYRAPEM-----I 218 Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228 G D+W++GV LY + PF G Sbjct: 219 NLYSGLGIDEKSDMWALGVLLYKLCYYTTPFETQG 253 >SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schizosaccharomyces pombe|chr 1|||Manual Length = 504 Score = 59.7 bits (138), Expect = 1e-09 Identities = 39/130 (30%), Positives = 69/130 (53%), Gaps = 7/130 (5%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76 LG GA V++ + + E VAVK + + + +E ++++VKH+N+V L Sbjct: 71 LGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNKKQRQGVFKEVNIMRRVKHKNVVNLFDF 130 Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD-NNLV 135 E ++ +VMEL GG LF+ + TY + ++++ + +KHL D +V Sbjct: 131 VETEDFYH--LVMELAEGGELFHQI--VNFTYFSENLARHIIIQ-VAEAVKHLHDVCGIV 185 Query: 136 HRDLKPGNIM 145 HRD+KP N++ Sbjct: 186 HRDIKPENLL 195 >SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein kinase Ppk5 |Schizosaccharomyces pombe|chr 1|||Manual Length = 836 Score = 59.7 bits (138), Expect = 1e-09 Identities = 58/234 (24%), Positives = 108/234 (46%), Gaps = 32/234 (13%) Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKV---- 65 Y + +GKG+ G V + ++ G+ VA+K + + H + E +LK++ Sbjct: 516 YRYEIIDTVGKGSFGQVLKCIDHKRGQVVAIKVIK--NRQKFHGQTLVEVGILKRLCEAD 573 Query: 66 --KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123 N+++ L+ + RG + ++ G +LF+++ EN Y + ++V Sbjct: 574 PADKNNVIRYLS---HFDFRGHLCIVTELLGSNLFDVIR--ENNY--KGLPLIVVKSFAL 626 Query: 124 AGMKHLR---DNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180 G++ LR N++H DLKP N++ ++ KL DFG++ E+ +Y Sbjct: 627 QGLQALRLLQGQNIIHCDLKPENLL--LSHPLKARIKLIDFGSSCFYNEK-----VY--- 676 Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKE 234 YL Y + +G +G +D+WS G L + TG +P P GG ++ Sbjct: 677 TYLQSRFYRAPEII--LGLEYGKEIDIWSFGCILAELFTG-VPLFP-GGNETEQ 726 >SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schizosaccharomyces pombe|chr 2|||Manual Length = 470 Score = 59.3 bits (137), Expect = 1e-09 Identities = 58/227 (25%), Positives = 100/227 (44%), Gaps = 25/227 (11%) Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVK-HENIVKL 73 S++G GA G V++ + +G AVK + + + +Q RE + +V H I+ L Sbjct: 22 SIIGAGAYGVVYKAEDIYDGTLYAVKALCKDGLNEKQKKLQARELALHARVSSHPYIITL 81 Query: 74 LAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133 + E ++ +V++ C G LF + + + Y + V L + ++H Sbjct: 82 HRVLETEDAI--YVVLQYCPNGDLFTYITE-KKVYQGNSHLIKTVFLQLISAVEHCHSVG 138 Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERA-- 191 + HRDLKP NIM + D T Y L DFG A F G+ Y+ P+ Sbjct: 139 IYHRDLKPENIM--VGNDVNTVY-LADFGLATTEPYSSDFGC--GSLFYMSPECQREVKK 193 Query: 192 ---------VLRKPV---GKSFG-ATVDLWSIGVTLYHVATGQLPFR 225 V +P+ SF A D+W++G+ L ++ + P++ Sbjct: 194 LSSLSDMLPVTPEPIESQSSSFATAPNDVWALGIILINLCCKRNPWK 240 >SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Schizosaccharomyces pombe|chr 2|||Manual Length = 423 Score = 58.8 bits (136), Expect = 2e-09 Identities = 55/214 (25%), Positives = 95/214 (44%), Gaps = 16/214 (7%) Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKV-KHENI 70 W +G G+ G V VN GE A+K + V+++ +L ++ +H NI Sbjct: 53 WIIKKTIGAGSMGKVKLVVNILTGEKAALKMIPFTPNNTSQTVRVQREALLGRLLRHPNI 112 Query: 71 VKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLR 130 ++ I+ + I+ E GG L + L E L + +L Sbjct: 113 CRV--IDCIRTPACTYILFEYVPGGQLLEYILARGK---LDEDLARSFAMQLINALVYLH 167 Query: 131 DNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYER 190 N +VHRDLK N++ + +D KL DFG + +++ + G+ + P++ + Sbjct: 168 KNFIVHRDLKIENVL--LTQDSRQV-KLIDFGLSNFYSKDDLLRTYCGSLYFAAPELLDA 224 Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 KP G VD+WS+GV +Y + G++PF Sbjct: 225 ----KPY---IGPEVDVWSLGVVIYVMVCGRVPF 251 >SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 3|||Manual Length = 781 Score = 58.4 bits (135), Expect = 2e-09 Identities = 39/146 (26%), Positives = 75/146 (51%), Gaps = 21/146 (14%) Query: 88 VMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKY 147 VM+ C G L ++++D + G +++E ++ + + G+ ++ + HRD+KP NI+ Sbjct: 536 VMDFCPRGDLLSLIEDRHDRLGKKDFECMI--KQILRGLNYIHSQGIAHRDIKPENIL-- 591 Query: 148 INEDGTTTYKLTDFGAAREL--------QEEEQFVSLYGTEEYLHPDMYERAVLRKPVGK 199 I+E G ++TDFGA L E + + ++G++ Y+ P+ +L Sbjct: 592 ISEYG--VLRITDFGACDVLCNPGDDITAVESKSMGIFGSDPYMAPE-----ILTPGSYN 644 Query: 200 SFGATVDLWSIGVTLYHVATGQLPFR 225 +F A D+WS + L+ + PFR Sbjct: 645 AFFA--DMWSTAIVLHCLYFRTYPFR 668 >SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyces pombe|chr 1|||Manual Length = 349 Score = 57.2 bits (132), Expect = 5e-09 Identities = 61/212 (28%), Positives = 91/212 (42%), Gaps = 22/212 (10%) Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ-LSHMRPHDVQMREFEVLKKVKHENI 70 +S +G GA G V ++ G VAVK + S RE ++LK ++HENI Sbjct: 20 YSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENI 79 Query: 71 VKLLAIEEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGMKHL 129 + L I V EL G L +L P T +Q + L + G+K + Sbjct: 80 ISLSDIFISPF-EDIYFVTELL-GTDLHRLLTSRPLETQFIQYF-----LYQILRGLKFV 132 Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189 ++HRDLKP NI+ INE+ K+ DFG AR ++ Q T Y P++ Sbjct: 133 HSAGVIHRDLKPSNIL--INEN--CDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEI-- 184 Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQ 221 + + VD+WS G + G+ Sbjct: 185 -----MLTWQKYNVEVDIWSAGCIFAEMIEGK 211 >SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 422 Score = 56.8 bits (131), Expect = 7e-09 Identities = 74/293 (25%), Positives = 122/293 (41%), Gaps = 35/293 (11%) Query: 18 LGKGATGAVF--QGVNKNNGEPVAVKTF-NQLSHMRPHDVQMREFEVLKKVK-HENIVKL 73 LG+GA G V + V + E VA+K N S +RE ++L + H NI + Sbjct: 27 LGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALREIKLLIHFRNHRNITCI 86 Query: 74 LAIEE-EQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132 ++ +V + E L I+ + L + F + + G+K++ Sbjct: 87 YDLDIINPYNFNEVYIYEELMEADLNAIIKSGQP---LTDAHFQSFIYQILCGLKYIHSA 143 Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAV 192 N++HRDLKPGN++ +N D K+ DFG AR E + + T EY+ Y Sbjct: 144 NVIHRDLKPGNLL--VNAD--CELKICDFGLARGCSENPEENPGFMT-EYVATRWYRAPE 198 Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG------------GRRNKETMFYIT 240 + S+ +D+WS+G L + G F+ G ++ET+ +I+ Sbjct: 199 IMLSF-SSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPDEETLSHIS 257 Query: 241 TKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHR 293 + +A + + PI + P L LLA LL DP+R Sbjct: 258 SSRAQEYV--RSLPKQRPIPFETNFPK-------ANPLALDLLAKLLAFDPNR 301 >SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosaccharomyces pombe|chr 3|||Manual Length = 477 Score = 56.8 bits (131), Expect = 7e-09 Identities = 53/225 (23%), Positives = 95/225 (42%), Gaps = 16/225 (7%) Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDV-QMREFEVLKKVKHENIVKLL 74 S LGKG V +++N + A+K M + ++ E L+ E ++ Sbjct: 163 SNLGKGMFSTVVSALDRNRNQTFAIKIIRNNEVMYKEGLKEVSILERLQAADREGKQHII 222 Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134 E + + ++ +L +IL GL L + + L+ N+ Sbjct: 223 HYERHFMHKNHLCMVFEMLSLNLRDILKKFGRNVGLSIKAVRLYAYQMFMALDLLKQCNV 282 Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194 +H D+KP N++ +NE K+ D G+A + E E L + Y P++ Sbjct: 283 IHSDIKPDNML--VNEK-RNILKICDLGSASDASENEITPYLV-SRFYRAPEII------ 332 Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239 +G + +D WS+G +LY + TGQ+ F GR N + + Y+ Sbjct: 333 --LGFPYSCPIDTWSVGCSLYELYTGQILF---PGRTNNQMLRYM 372 >SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schizosaccharomyces pombe|chr 1|||Manual Length = 690 Score = 56.4 bits (130), Expect = 1e-08 Identities = 52/225 (23%), Positives = 95/225 (42%), Gaps = 13/225 (5%) Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE--- 68 ++ +LG G G V Q +++ G A+K + R + + E VL+ + H Sbjct: 362 YTVVRLLGHGTFGKVIQCYDQSTGRHCAIKVTRAIPKYR--EASLIELRVLQTIAHSDPT 419 Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128 N K + + + + R + ++ G S+F+ L + N ++ + L + Sbjct: 420 NENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKN-NNYIPFPLKHIQMLSQQLFKSVAF 478 Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGT---EEYLHP 185 L LVH DLKP N++ N T ++ + + L E + +G+ E+ H Sbjct: 479 LHSLGLVHTDLKPENVLLVSNASRTIRLPYRNY-SQKVLNSCEIRLIDFGSATFEDEYHS 537 Query: 186 DMYERAVLRKP---VGKSFGATVDLWSIGVTLYHVATGQLPFRPY 227 + R P +G + D+WSIG L + TGQ F+ + Sbjct: 538 SVVSTRHYRAPEIILGLGWSYPCDVWSIGCILVELFTGQALFQTH 582 >SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase Ppk6|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 56.0 bits (129), Expect = 1e-08 Identities = 58/224 (25%), Positives = 100/224 (44%), Gaps = 27/224 (12%) Query: 12 WSTTSVLGKGATGAVFQGVNKNNG-EPVAVKTFNQL-----SHMRPHDVQMREFEV---- 61 ++T LG GA G V K+N V +K+ ++ S MR D+ E+ Sbjct: 503 YTTIKELGIGAYGQVKLATYKSNKVHEVILKSISKSRILLDSWMRDKDLGTVPMEISILH 562 Query: 62 -LKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120 LK H NIVK++ E+ E ++ E G ++ D E + E E + Sbjct: 563 FLKAHSHPNIVKMITFFEDNENY--YLLTEPQKPG--IDLFDYIELKPSISEKESKAIFF 618 Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180 + + HL +++HRD+K N++ +G +L DFG++ L + F + GT Sbjct: 619 QIALAVAHLHSFDIIHRDIKDENVIL----EGNGCARLIDFGSS-SLTKNGPFDTFRGTV 673 Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 + P++ LR K G D+W++G+ LY + + P+ Sbjct: 674 GFAAPEL-----LRGE--KYLGKEQDIWALGILLYTIVYRENPY 710 >SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizosaccharomyces pombe|chr 2|||Manual Length = 435 Score = 55.6 bits (128), Expect = 2e-08 Identities = 52/234 (22%), Positives = 106/234 (45%), Gaps = 10/234 (4%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 +G+G+ G +F G+N N + +A+K + S + R +++L V + I + Sbjct: 18 IGEGSFGVIFDGMNLLNNQLIAIKFEPKKSEAPQLRDEYRTYKLL--VGNAGIPNVYYF- 74 Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137 QEG ++V++L G SL ++ + + ++ + + + + ++ + + NLV+R Sbjct: 75 -GQEGLHNILVIDL-LGPSLEDLFEWCGRRFSVK--TVAMTAKQMLSRVQTIHEKNLVYR 130 Query: 138 DLKPGNIM--KYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195 D+KP N + + + + Y + DFG A+ ++ + + +E + Sbjct: 131 DIKPDNFLIGRPSSRNANMVY-MVDFGMAKYYRDPKTKQHIPYSERKSLSGTARYMSINT 189 Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGVIS 249 +G+ DL S+G + G LP++ NK I+ KK S IS Sbjct: 190 HLGREQSRRDDLESLGHVFMYFLRGSLPWQGLKAANNKHKYEKISEKKQSTSIS 243 >SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizosaccharomyces pombe|chr 1|||Manual Length = 532 Score = 55.2 bits (127), Expect = 2e-08 Identities = 55/216 (25%), Positives = 92/216 (42%), Gaps = 21/216 (9%) Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVK-TFN-QLSHMRPHDVQMREFEVLKKVKHEN 69 W LG+G V G + E VA+K +N +L RE +L+++ H N Sbjct: 23 WLLGRTLGQGNLAKVKLGKHFQTNEKVALKMVYNDELEDKDTWKRLQREVTILRQLHHPN 82 Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129 I+ L + K V+ L + + + N L E + + + + Sbjct: 83 IITLYQVFRVP----KYTVLALEYMDTDLHSMVVKHNR--LDECTTRKIFRQIVHAIDYC 136 Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189 + + HRDLK NI+ +N+D KLTDFG + + + + GT Y P++ + Sbjct: 137 HLHRVAHRDLKLENIL--LNKD--LVVKLTDFGLSNFMLDGSFLSTSCGTPHYAAPEVIQ 192 Query: 190 RAVLRKPVGKSF-GATVDLWSIGVTLYHVATGQLPF 224 G+ + G VD+W G+ LY + G+ PF Sbjct: 193 --------GRYYDGCDVDVWGCGILLYLMLVGEFPF 220 >SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosaccharomyces pombe|chr 1|||Manual Length = 439 Score = 55.2 bits (127), Expect = 2e-08 Identities = 52/229 (22%), Positives = 102/229 (44%), Gaps = 12/229 (5%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 +G+G+ G +FQGVN N +P+A+K ++ S + + +++L + V Sbjct: 21 IGEGSFGMLFQGVNLINNQPIALKFESRKSEVPQLRDEYLTYKLLMGLPGIPSVYYYG-- 78 Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137 QEG ++VM+L G SL ++ D + + ++ + + ++ + + + ++R Sbjct: 79 --QEGMYNLLVMDL-LGPSLEDLFDYCGRRFSPK--TVAMIAKQMITRIQSVHERHFIYR 133 Query: 138 DLKPGNIMKYINEDGTTTYKL---TDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194 D+KP N + I G+ T + DFG A++ ++ + V E + Sbjct: 134 DIKPDNFL--IGFPGSKTENVIYAVDFGMAKQYRDPKTHVHRPYNEHKSLSGTARYMSIN 191 Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243 +G+ DL S+G + G LP++ NK+ I KK Sbjct: 192 THLGREQSRRDDLESMGHVFMYFLRGSLPWQGLKAATNKQKYEKIGEKK 240 >SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 580 Score = 54.8 bits (126), Expect = 3e-08 Identities = 44/153 (28%), Positives = 77/153 (50%), Gaps = 19/153 (12%) Query: 5 RGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMR------ 57 +G E Y + +G GA V++ ++ GE VA+K + + P D + R Sbjct: 119 KGLEQY--TLLQKMGDGAFSNVYKAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESH 176 Query: 58 ----EFEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEY 113 E +++++VKH NI++LL E Q +V+EL GG LF+ + TY ++ Sbjct: 177 NILKEVQIMRRVKHPNIIQLL--EFIQTPEYYYLVLELADGGELFHQI--VRLTYFSEDL 232 Query: 114 EFLLVLEHLTAGMKHL-RDNNLVHRDLKPGNIM 145 V+ + +++L D +VHRD+KP N++ Sbjct: 233 S-RHVITQVAHAIRYLHEDCGVVHRDIKPENLL 264 >SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizosaccharomyces pombe|chr 1|||Manual Length = 646 Score = 54.8 bits (126), Expect = 3e-08 Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 18/212 (8%) Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKLL 74 ++GKG G V+ K+ A+K ++ +R +V + E ++L + + ++ Sbjct: 271 LIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSAADSPFIV 330 Query: 75 AIEEE-QEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133 A+ Q + +V + GG LF L + + E + L ++ L Sbjct: 331 ALRFSFQTPKDLYLVTDYMAGGELFWHL---QKSVRFPEERAKFYIAELLLALQALHKRG 387 Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAAR-ELQEEEQFVSLYGTEEYLHPDMYERAV 192 +V+RDLKP NI+ ++ G L DFG ++ L + GT +YL P+ V Sbjct: 388 IVYRDLKPENIL--LDVQGHIA--LCDFGLSKANLSVGTTTRTFCGTTDYLAPE-----V 438 Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 + G + VD WS+GV LY + G PF Sbjct: 439 ILDEAG--YDMMVDFWSLGVLLYEMTCGWSPF 468 >SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase Ppk21|Schizosaccharomyces pombe|chr 2|||Manual Length = 550 Score = 54.4 bits (125), Expect = 4e-08 Identities = 52/230 (22%), Positives = 99/230 (43%), Gaps = 26/230 (11%) Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63 ++ +YV+ ++G G+ V + +K + + A+K ++ ++ + V+ E Sbjct: 48 IKSPADYVFG--DIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERDS 105 Query: 64 KVKHENIVKLLAIEEE-QEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHL 122 ++ + + Q+ V+EL G L + + L E + Sbjct: 106 MMRLNGFPGISRLFHTFQDDLKLYYVLELAPNGELLQYI---KKYRFLDENCVRFYAAEI 162 Query: 123 TAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-------QEEEQFVS 175 + ++++ ++HRDLKP NI+ DG K+TDFG A+ L + F S Sbjct: 163 LSSIEYMHSCGIIHRDLKPENIL----FDGNMHVKITDFGTAKILPPKYVNSPDYTTFPS 218 Query: 176 LY-GTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 + GT EY+ P++ R V+ K + DLW+ +Y + G PF Sbjct: 219 SFVGTAEYVAPELLSRQVVSK--------SSDLWAFACVVYQMIVGSPPF 260 >SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 400 Score = 54.4 bits (125), Expect = 4e-08 Identities = 46/208 (22%), Positives = 93/208 (44%), Gaps = 10/208 (4%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 +G G+ G ++ G+N NGE VAVK + + + R + +LK ++ + Sbjct: 18 IGSGSFGQIYLGLNTVNGEQVAVKLEPLKARHHQLEYEFRVYNILKGNIGIPTIRWFGVT 77 Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137 +VM+L G SL ++ + L+ LL+ + L + ++++ + +HR Sbjct: 78 NSY----NAMVMDL-LGPSLEDLFCYCGRKFTLK--TVLLLADQLISRIEYVHSKSFLHR 130 Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197 D+KP N ++ + + + DFG A++ ++ + V + + A + + Sbjct: 131 DIKPDN---FLMKKHSNVVTMIDFGLAKKYRDFKTHVHIPYRDNKNLTGTARYASINTHI 187 Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFR 225 G DL S+G L + G LP++ Sbjct: 188 GIEQSRRDDLESLGYVLLYFCRGSLPWQ 215 >SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 54.4 bits (125), Expect = 4e-08 Identities = 56/213 (26%), Positives = 99/213 (46%), Gaps = 26/213 (12%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ-MREFEVLKKVKHENIVKLLAI 76 +G+G G V++ +N G+ VA+K + +RE ++L++++H+NIV+LL I Sbjct: 283 IGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKNIVRLLEI 342 Query: 77 EEEQEGRGKVI-VMELCTGGSLFN--ILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133 E+ V M+ G L N + P N L + F + +L Sbjct: 343 MVEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIF--------EALAYLHHRG 394 Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAAR--ELQEEEQFVSLYGTEEYLHPDMYERA 191 ++HRD+K NI+ +N +G K DFG AR + + + T + P++ Sbjct: 395 VLHRDIKGSNIL--LNNNG--DLKFADFGLARFNTSSKSANYTNRVITLWFRPPEL---- 446 Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 +L + ++ VD+WS G + + TG+ PF Sbjct: 447 LLGE---TAYDTAVDIWSAGCIVMELFTGK-PF 475 >SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces pombe|chr 3|||Manual Length = 496 Score = 54.0 bits (124), Expect = 5e-08 Identities = 43/159 (27%), Positives = 66/159 (41%), Gaps = 17/159 (10%) Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126 H+NI+ E + R +V+E GG LF D E G+ E L G+ Sbjct: 71 HKNIIHFYNTAENPQWRW--VVLEFAQGGDLF---DKIEPDVGIDEDVAQFYFAQLMEGI 125 Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPD 186 + + HRDLKP NI+ D K++DFG A S G L+ Sbjct: 126 SFMHSKGVAHRDLKPENILL----DYNGNLKISDFGFA-------SLFSYKGKSRLLNSP 174 Query: 187 MYERAVLRKPVGKSF-GATVDLWSIGVTLYHVATGQLPF 224 + + + + G+ VD+WS G+ L+ + G P+ Sbjct: 175 VGSPPYAAPEITQQYDGSKVDVWSCGIILFALLLGNTPW 213 >SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizosaccharomyces pombe|chr 3|||Manual Length = 338 Score = 54.0 bits (124), Expect = 5e-08 Identities = 55/217 (25%), Positives = 94/217 (43%), Gaps = 27/217 (12%) Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLL 74 +V+GKG+ VF ++ + A+K N+ H ++R E +L+ + H + K Sbjct: 34 NVIGKGSWSTVFVVKHRQTKQRFALKCINKKKHDEHKIKKLRNEVLLLQSLNHPLLCKFY 93 Query: 75 AIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133 + E E K+ +V +L GG L + + E + + L + + ++ Sbjct: 94 S---EFEDETKIYLVTDLMLGGDLRYHISQRK----FNESVIRIWMVELVSALIYIHSKG 146 Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL------QEEEQFVSLYGTEEYLHPDM 187 ++HRD+KP NI+ ++E G KL DF A ++ + V GT Y+ P+ Sbjct: 147 VLHRDVKPDNIL--LDEKGHC--KLADFNVAAKVHTSSSPSKSNMTVGRVGTPVYMAPET 202 Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 AV K D WS+G+T Y PF Sbjct: 203 LIHAVSYK--------ESDWWSLGITFYECLFQVRPF 231 >SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosaccharomyces pombe|chr 1|||Manual Length = 722 Score = 54.0 bits (124), Expect = 5e-08 Identities = 55/230 (23%), Positives = 98/230 (42%), Gaps = 36/230 (15%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKT--FNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75 +G G+ G +++ +G +A K F ++ + E +L+ +KH NIV+ Sbjct: 10 IGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEKQYIA-DEVNILRNLKHPNIVQYCG 68 Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGMK--HLRDN 132 E + + + ME C G L N++ E E E L L + H +N Sbjct: 69 EELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLALYRCHYGEN 128 Query: 133 -----------------NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVS 175 +++HRD+KP NI +++E+ + KL DFG ++ L F Sbjct: 129 APACDSQWPREIFHPKQSVLHRDIKPANI--FLDENNSV--KLGDFGLSKLLDNTRVFTQ 184 Query: 176 LY-GTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 Y GT Y+ P+ ++R + A D+W++G ++ + PF Sbjct: 185 SYVGTPYYMSPE-----IIR---SSPYSAKSDVWALGCVIFEICMLTHPF 226 >SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1023 Score = 52.8 bits (121), Expect = 1e-07 Identities = 52/180 (28%), Positives = 78/180 (43%), Gaps = 21/180 (11%) Query: 56 MREFEVLKKV--KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEY 113 MRE +LK + H +IVK L + + G IV++ GG LF+ + L++ Sbjct: 544 MREVAILKGLGNNHPHIVKYLDFVKTKHHFG--IVLDYVNGGELFDYILARRR---LEDS 598 Query: 114 EFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYK--LTDFGAARELQEE- 170 + L +G+ +L +VHRDLK NI+ N + T FG L E Sbjct: 599 VACRLFAQLISGVAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTFGHFNTLSEHS 658 Query: 171 ------EQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 + F + G+ Y P++ + G G D+WS GV LY + G LPF Sbjct: 659 LPTEKPDLFSTSCGSPCYAAPEL-----VNCKSGMYAGTQADIWSCGVILYAMLAGYLPF 713 >SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1072 Score = 52.4 bits (120), Expect = 2e-07 Identities = 47/159 (29%), Positives = 84/159 (52%), Gaps = 17/159 (10%) Query: 17 VLGKGATGA-VFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKV-KHENIVKLL 74 V+G G+ G V++GV ++ VAVK M +D+ RE +L++ H NIV+ Sbjct: 659 VIGYGSHGTIVYRGVYEDR--EVAVKRVL----MEFYDLASREITLLQQSDNHPNIVRYY 712 Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGL-QEYEFLLVLEHLTAGMKHLRDNN 133 +++ + IV+ELC +L ++++ P L + + + +L + G+ HL + Sbjct: 713 C--KQKSDQFLYIVIELCKC-NLSDLIEKPIAYDDLFKSIDLVSLLYQIAFGVSHLHSLD 769 Query: 134 LVHRDLKPGNIMKYINEDGTTTYK-----LTDFGAAREL 167 LVHRDLKP NI+ +N + ++DFG +++L Sbjct: 770 LVHRDLKPQNILLVVNNSPNLSKTRVRALISDFGLSKKL 808 >SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 891 Score = 52.0 bits (119), Expect = 2e-07 Identities = 36/138 (26%), Positives = 68/138 (49%), Gaps = 14/138 (10%) Query: 87 IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMK 146 +V E GG + + + L+E + + + + + +L N++VHRDLK NI+ Sbjct: 218 MVFEFVDGGQMLDYIISHGK---LKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENIL- 273 Query: 147 YINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVD 206 I++ G K+ DFG + + + + + G+ + P++ +P G VD Sbjct: 274 -ISKTGDI--KIIDFGLSNLYRRQSRLRTFCGSLYFAAPELLNA----QPY---IGPEVD 323 Query: 207 LWSIGVTLYHVATGQLPF 224 +WS G+ LY + G++PF Sbjct: 324 VWSFGIVLYVLVCGKVPF 341 >SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1316 Score = 52.0 bits (119), Expect = 2e-07 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 8/173 (4%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 + KG G V+ GE A+K ++ + + V + E + E + + Sbjct: 570 ISKGTFGTVYLSRKNTTGEIYAIKVLRKVDMISKNQVANVKAERAVLMAQEESAFVAKLY 629 Query: 78 EEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136 + R + +VME GG ++L ++ Y + E + + + G++HL ++H Sbjct: 630 YAFQSRDYLYLVMEFMNGGDCASLL---KSLYTIPESWAKIYIAEVALGLEHLHRLGIIH 686 Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189 RD+KP NI+ I T KL DFG ++ Q G L P ++ Sbjct: 687 RDIKPDNILMSI----TGHLKLADFGLSQLGLTTRQLRLQKGKNNILSPPSFQ 735 >SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizosaccharomyces pombe|chr 2|||Manual Length = 413 Score = 51.2 bits (117), Expect = 4e-07 Identities = 57/241 (23%), Positives = 97/241 (40%), Gaps = 32/241 (13%) Query: 7 SENYVWS-TTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR------EF 59 +E Y+WS T + + N + V LS ++ + R E Sbjct: 97 NEKYLWSINTKITSTEQREVLLVKSNNKKFDTSIVLKHTHLSSKSQNEKKARVKVFRQEI 156 Query: 60 EVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFL-LV 118 LK + H +V+LL ++V C GG L++ + + L EF+ + Sbjct: 157 WALKTLSHPCVVQLL--NYYVSSAELILVENYCMGGDLYHYTKKHHSDFSL---EFVGRI 211 Query: 119 LEHLTAGMKHLRDNNLVHRDLK--------PGNIMKYINE---DGTTTYKLTDFGAAREL 167 L + +L L+HRDLK P N++K I+ +++DF + + Sbjct: 212 FSELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIKTIDNWKNYPNALIQISDFELSIFV 271 Query: 168 QEEEQFV-SLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRP 226 + V S G++EY P++Y G D WS+G+ L+ + G+LPF Sbjct: 272 DSKNHLVQSSCGSQEYAPPEVYMGIA-------HDGFRADAWSLGIVLFALLEGRLPFDS 324 Query: 227 Y 227 Y Sbjct: 325 Y 325 >SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizosaccharomyces pombe|chr 2|||Manual Length = 446 Score = 50.8 bits (116), Expect = 5e-07 Identities = 50/229 (21%), Positives = 98/229 (42%), Gaps = 8/229 (3%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 +G+G+ G +F+G N N + VA+K + S + R +++L V Sbjct: 18 IGEGSFGVIFEGTNLLNNQQVAIKFEPRRSDAPQLRDEYRTYKLLAGCTGIPNVYYFG-- 75 Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137 QEG ++V++L G SL ++LD + ++ + + + A ++ + + +LV+R Sbjct: 76 --QEGLHNILVIDL-LGPSLEDLLDLCGRKFSVK--TVAMAAKQMLARVQSIHEKSLVYR 130 Query: 138 DLKPGN-IMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196 D+KP N ++ N + DFG + ++ + E+ + Sbjct: 131 DIKPDNFLIGRPNSKNANMIYVVDFGMVKFYRDPVTKQHIPYREKKNLSGTARYMSINTH 190 Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKAS 245 +G+ DL ++G + G LP++ NK+ I KK S Sbjct: 191 LGREQSRRDDLEALGHVFMYFLRGSLPWQGLKAATNKQKYERIGEKKQS 239 >SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 340 Score = 50.4 bits (115), Expect = 6e-07 Identities = 57/209 (27%), Positives = 94/209 (44%), Gaps = 23/209 (11%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 LG+G GAV + K+ +A KT S + +RE VL + IV Sbjct: 72 LGEGNGGAV--SLVKHRNIFMARKTVYVGSDSKLQKQILRELGVLHHCRSPYIVGFYGAF 129 Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFL-LVLEHLTAGMKHLRDN-NLV 135 + + + ME GSL IL + G + L ++ + G+ +L + +++ Sbjct: 130 QYKNNIS--LCMEYMDCGSLDAILREG----GPIPLDILGKIINSMVKGLIYLYNVLHII 183 Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195 HRDLKP N++ +N G KL DFG + EL + GT Y+ P+ Sbjct: 184 HRDLKPSNVV--VNSRGEI--KLCDFGVSGELVNSVA-QTFVGTSTYMSPERIR------ 232 Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224 G + D+WS+G+++ +AT +LP+ Sbjct: 233 --GGKYTVKSDIWSLGISIIELATQELPW 259 >SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizosaccharomyces pombe|chr 1|||Manual Length = 566 Score = 50.4 bits (115), Expect = 6e-07 Identities = 55/236 (23%), Positives = 97/236 (41%), Gaps = 27/236 (11%) Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKLL 74 +LGKG G V+ K +G+ A+K ++ ++ + + E +L H IV L Sbjct: 200 LLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILATSNHPFIVTLY 259 Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134 Q + ME C GG F L L E E + +TA +++L Sbjct: 260 --HSFQSDEYLYLCMEYCMGGEFFRALQRRPGRC-LSENEAKFYIAEVTAALEYLHLMGF 316 Query: 135 VHRDLKPGNIMKY-----INEDGTTTYKLTDFGAARELQ-------------EEEQFVSL 176 ++RDLKP NI+ + + D + + GA +Q + + ++ Sbjct: 317 IYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAYALDTKSCIAD 376 Query: 177 YGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRN 232 + T ++ + Y + K G + + VD W++G+ Y + PF+ G RN Sbjct: 377 FRTNSFVGTEEYIAPEVIKGCGHT--SAVDWWTLGILFYEMLYATTPFK--GKNRN 428 >SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizosaccharomyces pombe|chr 2|||Manual Length = 381 Score = 50.0 bits (114), Expect = 8e-07 Identities = 50/209 (23%), Positives = 81/209 (38%), Gaps = 19/209 (9%) Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76 VLG G+ G V Q K G P + L R + RE ++++ + H NI+KL+A Sbjct: 30 VLGSGSFGVVIQA--KLVGTPGFIAVKRVLQDKR---YKNRELQIMRAISHPNIIKLIAF 84 Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDD----PENTYGLQEYEFLLVLEHLTAGMKHLRDN 132 + L + DD + L L + +L Sbjct: 85 FHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHST 144 Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAV 192 + HRD+KP N++ + T KL DFG+A+ L E VS + Y P++ A Sbjct: 145 GVCHRDIKPQNLLV---DYKTGILKLCDFGSAKVLVPSEPNVSYICSRYYRAPELVFGAT 201 Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQ 221 + +D+WS + + G+ Sbjct: 202 -------HYTTKIDVWSAACVIAELFIGR 223 >SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 387 Score = 48.8 bits (111), Expect = 2e-06 Identities = 50/214 (23%), Positives = 90/214 (42%), Gaps = 21/214 (9%) Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71 ++++ V+G G+ G V Q + A+K Q + RE ++++ +KH NIV Sbjct: 32 YTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQDKRFKN-----RELQIMRIMKHPNIV 86 Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEY-----EFLLVLEHLTAGM 126 L+A + + L + + Y Q+ E L + L + Sbjct: 87 DLIAYYYTTGDNSDEVYLNLVLE-FMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSL 145 Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPD 186 ++ + + HRD+KP N++ E+G KL DFG+A+ L E VS + Y P+ Sbjct: 146 AYIHASGICHRDIKPQNLL-LDPENG--ILKLCDFGSAKILVAGEPNVSYICSRYYRAPE 202 Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATG 220 + A + +D+WS G + + G Sbjct: 203 LIFGAT-------DYTHAIDIWSTGCVMAELMLG 229 >SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 306 Score = 48.4 bits (110), Expect = 3e-06 Identities = 50/211 (23%), Positives = 96/211 (45%), Gaps = 22/211 (10%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 L G VF G KN+ + +K + PHD MR +L+ + H +I +++ Sbjct: 17 LTDGTISEVFVGERKNSKKLYVIKVQGLVFKRPPHDA-MRGKLILESIGHPHIERIVDSF 75 Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137 + E G V ++ L +++D+ + + +VL+ +++ +++L + ++HR Sbjct: 76 IDNEA-GSVYLITSFKSFVLSDVMDEISI-----DTKCKIVLQ-ISSALEYLEKHGILHR 128 Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQ----EEEQFVSLYGTEEYLHPDMYERAVL 193 D+ P NI+ ++ Y L+DF A Q E ++ + GT Y RA+ Sbjct: 129 DIHPNNIL--LDSMNGPAY-LSDFSIAWSKQHPGEEVQELIPQIGTGHY-------RAIE 178 Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 S+G VD W+ G+ + + + Q F Sbjct: 179 TLFGCHSYGHEVDRWTFGILIAELFSNQALF 209 >SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1087 Score = 48.4 bits (110), Expect = 3e-06 Identities = 47/214 (21%), Positives = 94/214 (43%), Gaps = 18/214 (8%) Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHEN 69 Y + LGKG+ G V + ++ G+ VA+K + R H + E ++L+K++ + Sbjct: 697 YRYEVVDFLGKGSFGQVLRCIDYETGKLVALKIIR--NKKRFHMQALVETKILQKIREWD 754 Query: 70 IVKLLAIEEEQEG---RGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126 + + + + R + V G +L+ ++ GL + L + Sbjct: 755 PLDEYCMVQYTDHFYFRDHLCVATELLGKNLYELIKS-NGFKGLPIVVIKSITRQLIQCL 813 Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPD 186 L + +++H DLKP NI+ + + K+ DFG++ E E + + Y P+ Sbjct: 814 TLLNEKHVIHCDLKPENIL--LCHPFKSQVKVIDFGSS--CFEGECVYTYIQSRFYRSPE 869 Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATG 220 + +G +G +D+WS+G + + TG Sbjct: 870 VI--------LGMGYGTPIDVWSLGCIIAEMYTG 895 >SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|Schizosaccharomyces pombe|chr 3|||Manual Length = 624 Score = 48.4 bits (110), Expect = 3e-06 Identities = 45/159 (28%), Positives = 76/159 (47%), Gaps = 15/159 (9%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKLLA 75 LG+G G+V+ +N E +A+K + + + ++V+ + E ++L E +VKL Sbjct: 168 LGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHILNERDILTNTNSEWLVKLYY 227 Query: 76 IEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGL-QEYEFLLVLEHLTAGMKHLRDNN 133 +++E KV + ME GG L T GL E + L + A + + Sbjct: 228 AFQDKE---KVYLAMEYVPGGDFRTFL----TTKGLLHENQTRFYLAEMVAAISAVHKLG 280 Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ 172 +HRDLKP N + I++ G KL+DFG + + Q Sbjct: 281 YMHRDLKPENFL--IDQKG--HIKLSDFGLSTAIVTSNQ 315 Score = 33.9 bits (74), Expect = 0.058 Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 8/57 (14%) Query: 168 QEEEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 + E + S+ G+ EY+ P++ GK + TVD WS+G Y G PF Sbjct: 349 KNENKVNSVVGSPEYMAPEVV--------YGKKYDRTVDYWSLGCICYECLVGYPPF 397 >SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase Srb10 |Schizosaccharomyces pombe|chr 1|||Manual Length = 352 Score = 48.0 bits (109), Expect = 3e-06 Identities = 50/206 (24%), Positives = 92/206 (44%), Gaps = 22/206 (10%) Query: 18 LGKGATGAVFQGVNKNNGEP--VAVKTFNQLSHMRPHDVQ--------MREFEVLKKVKH 67 + G G V++ V+ N+ + A+K F S + Q +RE + ++++H Sbjct: 11 ISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMMLCREIQH 70 Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLL--VLEHLTAG 125 ENIV L+ + + G + ++ L I+ + Q +L +L + G Sbjct: 71 ENIVSLVQVLLKD---GTISMVFEYAEHDLLQIIHFHSRSRTRQIPPSILKSILWQIING 127 Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185 + +L +N ++HRDLKP NIM I G K+ D G R ++ + + Y ++ + Sbjct: 128 VAYLHENWIMHRDLKPANIM--ITATGKV--KIGDLGLGRLIR--DPILPFYSSDRVVVT 181 Query: 186 DMYERAVLRKPVGKSFGATVDLWSIG 211 Y RA + +D+W+IG Sbjct: 182 IWY-RAPELLLGAHDYTPAIDVWAIG 206 >SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosaccharomyces pombe|chr 3|||Manual Length = 592 Score = 47.2 bits (107), Expect = 6e-06 Identities = 54/228 (23%), Positives = 92/228 (40%), Gaps = 39/228 (17%) Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQ---LSHMRPHDVQMREFEVLKKVKHENIVKL 73 +LG+G+ V + A+K ++ + + V + + + KH +KL Sbjct: 104 ILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCILSKHPGFIKL 163 Query: 74 LAIEEEQEGRGKVIVMELCTGGSLFNILDDPE--NTYGLQEYEFLLVLEHLTAGMKHLRD 131 Q+ V+ L G L + ++ N Q Y L+V + ++ Sbjct: 164 FYTF--QDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIV-----DSIDYMHG 216 Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL------QEEE---------QFVSL 176 ++HRDLKP NI+ +D T K+TDFG+A+ L EE+ S Sbjct: 217 RGVIHRDLKPENILL---DDNMRT-KITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSF 272 Query: 177 YGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 GT Y+ P++ K G D+W+ G L+ + G+ PF Sbjct: 273 VGTARYVSPEVLS--------DKIAGTASDIWAFGCILFQMLAGKPPF 312 >SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomyces pombe|chr 1|||Manual Length = 607 Score = 46.0 bits (104), Expect = 1e-05 Identities = 40/167 (23%), Positives = 77/167 (46%), Gaps = 11/167 (6%) Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHEN 69 + T + +G+G G+V+ ++ E VA+K N+ + +++ + E ++L E Sbjct: 208 FQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSVLHKMDEIRHVLTERDILTTANSEW 267 Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129 +V+LL Q+ + ME GG +L N+ L+++ + + L Sbjct: 268 LVRLL--YAFQDTSNIYLAMEFVPGGDFRTLL---SNSGVLRDHHAKFYATEMFLAIDAL 322 Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSL 176 +HRDLKP N + + G KLTDFG + + +++ S+ Sbjct: 323 HQLGYIHRDLKPENFL--VGASG--HIKLTDFGLSSGIISKKKIESM 365 Score = 33.1 bits (72), Expect = 0.10 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 11/61 (18%) Query: 175 SLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKE 234 S+ G+ +Y+ P+ VLR G+++ +VD WS+G +Y +G F P+ G E Sbjct: 402 SVVGSPDYMAPE-----VLR---GENYNHSVDYWSLGCIMYECLSG---FPPFSGSNVNE 450 Query: 235 T 235 T Sbjct: 451 T 451 >SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1338 Score = 46.0 bits (104), Expect = 1e-05 Identities = 37/152 (24%), Positives = 75/152 (49%), Gaps = 14/152 (9%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTF---NQLSHMRPHDVQMREFEVLKKVKHENIVKLL 74 + KGA G+V+ + G+ A+K N ++ + +V+ ++ + + + KL Sbjct: 595 ISKGAFGSVYLAQKRTTGDYFAIKILKKSNMIAKNQVINVRAERAILMSQGESPFVAKLY 654 Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLV-LEHLTAGMKHLRDNN 133 + ++ +VME GG ++L T G+ + +++ + + L D Sbjct: 655 YTFQSKDYL--YLVMEYLNGGDCGSLL----KTMGVLDLDWIRTYIAETVLCLGDLHDRG 708 Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAAR 165 ++HRD+KP N++ I+++G KLTDFG +R Sbjct: 709 IIHRDIKPENLL--ISQNG--HLKLTDFGLSR 736 >SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Schizosaccharomyces pombe|chr 2|||Manual Length = 297 Score = 45.6 bits (103), Expect = 2e-05 Identities = 59/214 (27%), Positives = 91/214 (42%), Gaps = 28/214 (13%) Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRP-HDVQMREFEVLKKVK 66 ENY +G+G G V++ +K +G VA+K +RE +LK+V Sbjct: 2 ENY--QKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVN 59 Query: 67 HEN----IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE-- 120 EN V+LL I + K+ ++ L +D T G + LV + Sbjct: 60 DENNRSNCVRLLDILHAES---KLYLVFEFLDMDLKKYMDRISET-GATSLDPRLVQKFT 115 Query: 121 -HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGT 179 L G+ ++HRDLKP N++ I+++G KL DFG AR V L Sbjct: 116 YQLVNGVNFCHSRRIIHRDLKPQNLL--IDKEG--NLKLADFGLARSFG-----VPL--- 163 Query: 180 EEYLHP--DMYERAVLRKPVGKSFGATVDLWSIG 211 Y H ++ RA + + VD+WS+G Sbjct: 164 RNYTHEIVTLWYRAPEVLLGSRHYSTGVDIWSVG 197 >SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 45.2 bits (102), Expect = 2e-05 Identities = 43/157 (27%), Positives = 67/157 (42%), Gaps = 26/157 (16%) Query: 86 VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT--AGMKHLRDNNLVHRDLKPGN 143 ++++E C G L + L+ L E E L + +T + H L+HRDLK N Sbjct: 113 LVLLEYCPCGGLIDFLNTRLQVR-LSEQEILKIASDVTEAVAVMHYLKPPLIHRDLKIEN 171 Query: 144 IMKYINEDGTTTYKLTDFGAA----------RELQEEEQFVSLYGTEEYLHPDMYERAVL 193 ++ +YKL DFG+A E ++ E + + T +Y P+M Sbjct: 172 VLLA----APNSYKLCDFGSACHPIPGAKTAAEAKQLEYDIEKFTTWQYRCPEMIN---- 223 Query: 194 RKPVGKSFGATV--DLWSIGVTLYHVATGQLPFRPYG 228 V K FG D+W++GV Y + PF G Sbjct: 224 ---VHKGFGIDEKSDIWALGVLFYKLCYYTTPFEHQG 257 >SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 45.2 bits (102), Expect = 2e-05 Identities = 57/218 (26%), Positives = 93/218 (42%), Gaps = 27/218 (12%) Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR----EFEVLKKVKHENIVK 72 +LG GA G+V ++G+ AVK F R EF + + H NI++ Sbjct: 307 MLGSGAGGSVRIMKRSSDGKIFAVKEFRARRPTETEREYARKVTAEFCIGSALHHTNIIE 366 Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132 L I EE + +V ME +F+I+ + T E + L +G+ +L Sbjct: 367 TLDIVEENKKFYEV--MEYAPY-DMFSIVMSGKMTMP----EVYCCFKQLLSGVAYLHSM 419 Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ-----EEEQFVSLYGTEEYLHPDM 187 L HRDLK N++ D K+ DFG+A + + + + G++ YL P+ Sbjct: 420 GLAHRDLKLDNLV----VDSNCFVKIIDFGSAVVFKYPFEADIVEATGVVGSDPYLAPET 475 Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225 R L P VD+WS + +A + P++ Sbjct: 476 LVRK-LYDP------RAVDIWSSAIIFCCMALRRFPWK 506 >SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomyces pombe|chr 2|||Manual Length = 581 Score = 44.4 bits (100), Expect = 4e-05 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 13/131 (9%) Query: 89 MELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYI 148 ++ C G L L + + + +L LT + + VH D+KP N++ I Sbjct: 368 LDYCENGDLSLFLSELGLLQVMDPFRVWKMLFQLTQALNFIHLLEFVHLDVKPSNVL--I 425 Query: 149 NEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLW 208 DG KL DFG A L V L G Y+ P++ ++G D++ Sbjct: 426 TRDG--NLKLGDFGLATSL-PVSSMVDLEGDRVYIAPEIL--------ASHNYGKPADVY 474 Query: 209 SIGVTLYHVAT 219 S+G+++ AT Sbjct: 475 SLGLSMIEAAT 485 >SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gcn2 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1576 Score = 44.0 bits (99), Expect = 5e-05 Identities = 42/168 (25%), Positives = 77/168 (45%), Gaps = 30/168 (17%) Query: 66 KHENIVKLLAIEEEQEGRGKV--IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123 K +I + +++ ++ G I ME C SL +I+ D + E + + Sbjct: 703 KDSSIEEASSVKTQENGLNATLYIQMEYCEKLSLQDIIRDK-----IPVDEMWRLFRQIL 757 Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQE-------------- 169 + ++ ++HRDLKPGNI +++E+ KL DFG A E + Sbjct: 758 EALAYIHSRGMMHRDLKPGNI--FLDEN--RNVKLGDFGLATENENYQDNNDKWKNRQSA 813 Query: 170 EEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHV 217 +E + GT Y+ P++ L + G + A VD++S+G+ L+ + Sbjct: 814 DEDLTTGVGTALYVAPEL-----LSRRNGVRYDAKVDMYSLGIILFEM 856 Score = 34.3 bits (75), Expect = 0.044 Identities = 21/69 (30%), Positives = 33/69 (47%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77 LG+G G V + N+ +G AVK LS + + +RE L ++ HE++V+ Sbjct: 562 LGRGGFGEVVKVKNRIDGRFYAVKKLVLLSDDKENSRILREVMTLSRLHHEHVVRYYTAW 621 Query: 78 EEQEGRGKV 86 E E V Sbjct: 622 VETEANDTV 630 Score = 32.7 bits (71), Expect = 0.13 Identities = 27/116 (23%), Positives = 51/116 (43%), Gaps = 8/116 (6%) Query: 58 EFEVLKKVKHENIVKLLAIEEEQEGRG----KVIVMELCTGGSLFNILDDPENTYGLQEY 113 E E LK ++H+ + + + E+E RG ++ E +LF++L + L Sbjct: 293 ELESLKVIRHDLLASIYEYQLERETRGYGWRLYVLQEYSPKFTLFSLL---QTVLTLDVE 349 Query: 114 EFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQE 169 ++ G+ L + H+ L N++ + + T KL DFG R L++ Sbjct: 350 TVRAFSNNILEGLAELHRLGISHKSLHLDNVVLF-HSGHRTFAKLMDFGFTRTLRD 404 >SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosaccharomyces pombe|chr 1|||Manual Length = 469 Score = 42.7 bits (96), Expect = 1e-04 Identities = 40/164 (24%), Positives = 73/164 (44%), Gaps = 7/164 (4%) Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71 +ST V+GKGA G V + G+ A+K+ + + + + E V+ ++ Sbjct: 93 FSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAERDLLVESDSPW 152 Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131 + Q+ ++ME GG L +L + + T+ F + + + Sbjct: 153 VVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYD-TFSEDVTRFYMA--ECVLAIADVHR 209 Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVS 175 +HRD+KP NI+ I+ DG KL+DFG + +++Q S Sbjct: 210 MGYIHRDIKPDNIL--IDRDG--HIKLSDFGLSTGFYKQDQSAS 249 Score = 27.1 bits (57), Expect = 6.7 Identities = 13/50 (26%), Positives = 24/50 (48%), Gaps = 8/50 (16%) Query: 175 SLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224 S GT +Y+ P+++ + + +G D WS+G ++ G PF Sbjct: 291 STVGTPDYIAPEIF--------LQQGYGQDCDWWSLGAIMFECLIGWPPF 332 >SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Schizosaccharomyces pombe|chr 1|||Manual Length = 332 Score = 42.3 bits (95), Expect = 2e-04 Identities = 40/196 (20%), Positives = 80/196 (40%), Gaps = 21/196 (10%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKH-ENIVKLLAI 76 +G+G VF+G+N N +K + + + RE ++L+ + NI+ LL I Sbjct: 49 VGRGKYSEVFEGLNVLNNSKCIIKVLKPVKYKKIK----REIKILQNLAGGPNIISLLDI 104 Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136 + E + ++ E F L + Y ++ Y + L + ++H Sbjct: 105 VRDPESKTPSLIFEFVDNID-FRTLYPTLSDYDIRYYSY-----ELLKALDFCHSRGIMH 158 Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196 RD+KP N+M + +L D+G A ++ + + P++ Sbjct: 159 RDVKPHNVM---IDHKKRKLRLIDWGLAEFYHAGMEYNVRVASRYFKGPELLVDF----- 210 Query: 197 VGKSFGATVDLWSIGV 212 + + ++D+WS GV Sbjct: 211 --REYDYSLDIWSFGV 224 >SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces pombe|chr 1|||Manual Length = 639 Score = 41.1 bits (92), Expect = 4e-04 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75 S+LG+G G+V+ NK +G A+K N + RE + L K+ H N+++ + Sbjct: 175 SLLGRGGFGSVYHVRNKIDGAEYAMKKINSTFQQMSYSKIFREIKCLAKMDHPNVIRYFS 234 Query: 76 --IEEEQEGRGKVIVM 89 +E E IVM Sbjct: 235 SWVESTTEATQMPIVM 250 Score = 27.1 bits (57), Expect = 6.7 Identities = 12/21 (57%), Positives = 15/21 (71%), Gaps = 2/21 (9%) Query: 133 NLVHRDLKPGNIM--KYINED 151 NL+HRD+KP NI K + ED Sbjct: 412 NLIHRDIKPSNIFLAKSLPED 432 >SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1032 Score = 39.5 bits (88), Expect = 0.001 Identities = 41/185 (22%), Positives = 83/185 (44%), Gaps = 18/185 (9%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVK-----TFNQLSHMRPHDVQMREFEVLKKVKHENIVK 72 + +GA G V+ +++G+ A+K + + L ++ ++ R + + N VK Sbjct: 534 INRGAYGRVYLAKKRSSGKYFALKMIPKSSLDSLKKIKGLLLEKRNMHIQRY--GPNTVK 591 Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132 L + G +VM+ GG ++ + L E L ++ L + Sbjct: 592 LYYAFDS--GDYLCLVMDYFNGGDCETLI---QKLGPLPEQWVCQYAAELLNAIELLHQD 646 Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYG--TEEYLHPDMYER 190 ++H D+KP N++ D T +LTDFG + ++E+++ L + E H ++YE+ Sbjct: 647 GIIHHDIKPANML----VDETGHIRLTDFGLSENVEEKKEVYKLTKRMSFEQKHGNLYEQ 702 Query: 191 AVLRK 195 +K Sbjct: 703 LQPKK 707 >SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizosaccharomyces pombe|chr 1|||Manual Length = 513 Score = 39.1 bits (87), Expect = 0.002 Identities = 56/238 (23%), Positives = 106/238 (44%), Gaps = 32/238 (13%) Query: 16 SVLGKGATGAVFQGVNKNNGEPVAV-KTFN---QLSHMRPH-DVQMREFEVLKKVKHENI 70 +V+G+GA+ + + +N N P+ V K F S +R + + E+ ++H NI Sbjct: 245 NVIGEGASSFI-RVINDRNKLPIYVAKVFRPPLDTSLLRRYVRYFIAEYTFASTLRHPNI 303 Query: 71 VKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLR 130 +K+L I + R ++ + LF + + + F +L+ G+ ++ Sbjct: 304 IKVLDIIYK---RHTILQIIEYVPYDLFTFITKGHCSALKADQMFFQLLD----GVAYMH 356 Query: 131 DNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQ---EEEQFVS--LYGTEEYLHP 185 + HRD+K NIM D K+ DFG A E +S + G++ Y+ P Sbjct: 357 SLGIAHRDIKLDNIML----DENLNVKIIDFGTAFVFHYPFESTTLMSDGVVGSKPYVAP 412 Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR-PYGGRRNKETMFYITTK 242 ++ + +KP S VD+WS + +A + P++ P+ +K Y+T + Sbjct: 413 EV----LTQKPYDPS---AVDVWSCAIVYCCIALKRFPWKVPH--TSDKRFNLYVTQR 461 >SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizosaccharomyces pombe|chr 1|||Manual Length = 534 Score = 36.7 bits (81), Expect = 0.008 Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 13/105 (12%) Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMY 188 L+ ++H DLKP NI+ + + + K+ DFG+A E + + + Y P++ Sbjct: 248 LKQARIIHCDLKPENIL--LQDLSSPIVKVIDFGSA--CHERQTVYTYIQSRFYRSPEVI 303 Query: 189 ERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNK 233 +G + +D+WS+G L + G LP P N+ Sbjct: 304 --------LGLHYNCGIDMWSLGCILAELFLG-LPLFPGNSEYNQ 339 >SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosaccharomyces pombe|chr 2|||Manual Length = 429 Score = 33.1 bits (72), Expect = 0.10 Identities = 34/148 (22%), Positives = 61/148 (41%), Gaps = 16/148 (10%) Query: 12 WSTTSVLGKGATGAVFQGVNKN-NGEPVAVKTFNQLSHMRPHDVQMR---EFEVLKKVKH 67 + ++G G+ +VF+ V+++ + + +Q+ PHD R F LK++ Sbjct: 40 YHVVKLVGAGSFSSVFKAVDRHFDSYDNSYWISSQIEDQMPHDKTKRPKNHFVALKRIYA 99 Query: 68 ENIVKLLAIEEEQ--EGRGKVIVMELCTGGS-------LFNILDDPENTYGLQEY---EF 115 + + E E E RG V+ + T + + E +Y E Sbjct: 100 TVLPSRIQTELEMLHELRGSDCVLNMITAVRHQDQVLIVLPFIQHAEFRDFYMKYSLPEI 159 Query: 116 LLVLEHLTAGMKHLRDNNLVHRDLKPGN 143 L L G+ H+ ++HRD+KPGN Sbjct: 160 GAYLRDLLKGLAHIDAKGIIHRDIKPGN 187 >SPBC354.13 |rga6||GTPase activating protein Rga6|Schizosaccharomyces pombe|chr 2|||Manual Length = 733 Score = 31.9 bits (69), Expect = 0.23 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 3/84 (3%) Query: 366 NENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEPDPPKFPVFPNMVSVENDASQAKVSSG 425 N N +SYP+ L L N +++N S E D +V V+N Q K+S+ Sbjct: 586 NVNASEESYPNVKHISKLPLINDSSDNESGNQENDDAVANESTKVV-VDNQQPQPKISTV 644 Query: 426 AKTARPALD--RSMSSRRYKVAQT 447 + TA P++ ++SSR A T Sbjct: 645 SDTAVPSMSFANNISSRSVISAAT 668 >SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces pombe|chr 1|||Manual Length = 704 Score = 31.9 bits (69), Expect = 0.23 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 1/60 (1%) Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75 +LGKG G+V++ NK +G A+K +L RE L ++ H N+++ + Sbjct: 229 LLGKGGYGSVYKARNKFDGVEYALKKIPLRLRSFSTSSNIFRESRTLARLNHPNVIRFFS 288 Score = 30.3 bits (65), Expect = 0.71 Identities = 14/31 (45%), Positives = 21/31 (67%), Gaps = 1/31 (3%) Query: 115 FLLVLEHLTAGMKHLRDN-NLVHRDLKPGNI 144 ++L+ + G+ +L D +LVHRDLKP NI Sbjct: 467 YILLFARILEGVLYLHDAMHLVHRDLKPRNI 497 >SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 544 Score = 31.1 bits (67), Expect = 0.41 Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 25/150 (16%) Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKV-----KH---EN 69 LG G V+ ++ VA+K H R + + E +L+K+ KH ++ Sbjct: 87 LGWGHFSTVWLAYDRAAKRRVALKVVRSAEHYR--ETSIDEIRILQKIREGDEKHLGKKH 144 Query: 70 IVKLLA--IEEEQEGRGKVIVMELCTGGSLFNILDD------PENTYGLQEYEFLLVLEH 121 I+ LL + G +V E+ G +L +++ P Y+ L+ L++ Sbjct: 145 IISLLDYFVHRGPNGAHVCMVFEVL-GENLLSLIQSYGHRGVPVGIVKQIAYQLLIALDY 203 Query: 122 LTAGMKHLRDNNLVHRDLKPGNIMKYINED 151 L H R+ ++H DLKP N++ I++D Sbjct: 204 L-----H-RECGIIHTDLKPENVLICIDQD 227 Score = 29.9 bits (64), Expect = 0.94 Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 10/75 (13%) Query: 155 TYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTL 214 T K+ D G A + F + T +Y P++ +G +GA+ D WS + Sbjct: 355 TVKIADLGNA--CWTRKHFTNDVQTRQYRSPEVI--------LGCRWGASADCWSFACII 404 Query: 215 YHVATGQLPFRPYGG 229 + + TG F P G Sbjct: 405 FELLTGDYLFDPRNG 419 >SPBC13G1.12 |did2||vacuolar sorting protein Did2|Schizosaccharomyces pombe|chr 2|||Manual Length = 178 Score = 29.5 bits (63), Expect = 1.2 Identities = 18/32 (56%), Positives = 21/32 (65%), Gaps = 2/32 (6%) Query: 377 TSADEPLLLFNKN-NNNVSMPAEPDP-PKFPV 406 T ADE L FN+N NNN+S+PA P P PV Sbjct: 133 TVADEAGLEFNQNMNNNLSVPAASVPTPAAPV 164 >SPBC713.02c |ubp21|ubpD, ubp15|ubiquitin C-terminal hydrolase Ubp21|Schizosaccharomyces pombe|chr 2|||Manual Length = 1129 Score = 29.5 bits (63), Expect = 1.2 Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 2/63 (3%) Query: 60 EVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLV 118 E LK +K + + K L + Q + K+ V++ + G + + DD E YG L+ +L Sbjct: 1049 ETLKDLK-KRLQKRLGYNDTQFSKVKLAVLQAQSFGKPYYLTDDDEVLYGELEPQSHILG 1107 Query: 119 LEH 121 L+H Sbjct: 1108 LDH 1110 >SPAC3H1.01c |orp3|orc3, SPAP14E8.06c|origin recognition complex subunit Orp3 |Schizosaccharomyces pombe|chr 1|||Manual Length = 690 Score = 29.5 bits (63), Expect = 1.2 Identities = 17/70 (24%), Positives = 36/70 (51%), Gaps = 1/70 (1%) Query: 81 EGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRDLK 140 E GK ++ L L+ + + L ++ ++ EHL AG ++L++++ R+ Sbjct: 575 EKDGKDLISWLPDLSILYKLYSESGALLNLYDW-YIAFSEHLQAGKENLKEDDNHPRESP 633 Query: 141 PGNIMKYINE 150 GN+ + +NE Sbjct: 634 QGNLQRELNE 643 >SPBC28F2.07 |sfr1|dds20, mug13|Swi five-dependent recombination repair protein Sfr1|Schizosaccharomyces pombe|chr 2|||Manual Length = 299 Score = 29.1 bits (62), Expect = 1.6 Identities = 31/137 (22%), Positives = 59/137 (43%), Gaps = 9/137 (6%) Query: 369 TPGKSYPDTSADEPLLLFNKNNNNVSMPAEPDPPKFPVFPNMVSVENDASQAKVSSGAKT 428 T DT+ L + N N++ + +EP PN + + ++ +S+ Sbjct: 114 TASPQVADTNLKPSLAVTNLNSDETNTSSEPVTSPLRTTPNSIKRQKRLFKSPISNCLNP 173 Query: 429 ARPALDRSMSSRRYKVAQTV-YLQTQILDKDVSAAEIKLVALTERLQDAELKIRDAVSEA 487 + SRR K+ + V LQ Q++ + + K+ A E D +L + + + Sbjct: 174 KSDPEITQLLSRRLKLEKEVRNLQEQLITAETAR---KVEAKNE---DKDL--QTLIQKW 225 Query: 488 KNASKTSAAVKIEASAE 504 KNA++ +A V + AE Sbjct: 226 KNAAQQAAEVLFKPMAE 242 >SPBC336.15 |pic1|SPBC685.01|INCENP-like|Schizosaccharomyces pombe|chr 2|||Manual Length = 1018 Score = 28.7 bits (61), Expect = 2.2 Identities = 26/105 (24%), Positives = 50/105 (47%), Gaps = 2/105 (1%) Query: 337 LHTYVCEQTSVVAESQILLYKDWLLTS-EVNENTPGKSYPDTSADEPLLLFNKN-NNNVS 394 LH+ V S + + KD L + E++ + P K+ P T++D P L N N +++ S Sbjct: 229 LHSRVESTNSFINQLNRRRTKDNLTNNPEISLDEPIKALPSTTSDAPSSLLNTNVSSSPS 288 Query: 395 MPAEPDPPKFPVFPNMVSVENDASQAKVSSGAKTARPALDRSMSS 439 + P ++ + E+ S ++S+ KT + + + SS Sbjct: 289 KFRKFLSSVIPAKTDLSAKESLTSSTRLSTSYKTRKRSSGVAFSS 333 >SPCC1902.01 |gaf1|SPCC417.01c|transcription factor Gaf1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 855 Score = 28.7 bits (61), Expect = 2.2 Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 4/75 (5%) Query: 369 TPGKSY-PDTSADEPLLLFNKNNNNVSMPAEPDPPKFPVFP--NMVSVENDASQAKVSSG 425 TP +S+ PD S + + ++NN+ VS P P + P NMVS ++ S+ Sbjct: 358 TPNQSFFPDVSGNN-IFDVSRNNHEVSSPLIQSPGSYVSMPSINMVSSLPISAPVPNSNS 416 Query: 426 AKTARPALDRSMSSR 440 RP R+ SS+ Sbjct: 417 QFPRRPNTFRTNSSK 431 >SPBC1718.01 |pop1|ste16, SPBC2G2.18|F-box/WD repeat protein Pop1|Schizosaccharomyces pombe|chr 2|||Manual Length = 775 Score = 28.3 bits (60), Expect = 2.9 Identities = 39/165 (23%), Positives = 64/165 (38%), Gaps = 19/165 (11%) Query: 242 KKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFF 301 K+ S I G + D + + C + + T +L LE +WTFE + Sbjct: 397 KRCSFPIHGVRLITKLQFDDDKIIVSTCSPRINIYDTKTGVLIRSLEEHEGDVWTFE-YV 455 Query: 302 SEVQVVTST-KPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWL 360 + V ST + V V+ + +VF YGH T C +V +Q D Sbjct: 456 GDTLVTGSTDRTVRVWDLRTGECKQVF------YGHTSTIRC--IKIVQGNQSTTDTD-- 505 Query: 361 LTSEVNENTPGKSYPDTSADEPLLLFNKNNNNV---SMPAEPDPP 402 EN P + D ++ P ++ + + + S+P DPP Sbjct: 506 --DVEKENRPASN--DANSMPPYIISSSRDCTIRLWSLPCLDDPP 546 >SPAC139.05 |||succinate-semialdehyde dehydrogenase |Schizosaccharomyces pombe|chr 1|||Manual Length = 493 Score = 27.5 bits (58), Expect = 5.0 Identities = 18/82 (21%), Positives = 41/82 (50%), Gaps = 1/82 (1%) Query: 13 STTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVK 72 +T ++GK A +V + + A KT+ +H++ + R E++ + K +++VK Sbjct: 41 ATGEIIGKVADVSVEETKKAISAANEAFKTYKNFTHVQRSQLLERWAELIMENK-DDLVK 99 Query: 73 LLAIEEEQEGRGKVIVMELCTG 94 +L +E + + + C+G Sbjct: 100 MLTLENGKPLSQAEMEVTTCSG 121 >SPAP27G11.07c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 238 Score = 27.5 bits (58), Expect = 5.0 Identities = 17/78 (21%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 112 EYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEE 171 E + + +++ + + + + N++VH DL N+M + + + G+ E EE+ Sbjct: 122 EKKLIPLMKRIGSEVAKMHKNDIVHGDLTTSNMMLESHNNPVPIFIDFGLGSVSE-SEED 180 Query: 172 QFVSLYGTEEYLHPDMYE 189 + V +Y E L + E Sbjct: 181 KAVDIYVLERALSSTLPE 198 >SPAC26A3.05 |chc1||clathrin heavy chain Chc1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1666 Score = 27.1 bits (57), Expect = 6.7 Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 3/52 (5%) Query: 95 GSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMK 146 GS+ NI +DPE Y + + ++ T + RDNN V+ K N++K Sbjct: 713 GSIVNITEDPEVVY--KYIQAACLMNQFTEVERICRDNN-VYNPEKVKNLLK 761 >SPAC30.04c |abc4||glutathione S-conjugate-exporting ATPase Abc4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1469 Score = 27.1 bits (57), Expect = 6.7 Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 4/55 (7%) Query: 371 GKSYPDTSADEPLLLFNKNNNNVSMPAEPDPPKFPVFPNMVSVENDASQAKVSSG 425 G ++P T PLL + + S A PD P+ PN V +DA A G Sbjct: 816 GSAFPVTDKSSPLLFLAEQAASASEAAAPDLAAIPI-PNEV---DDAEAADEKDG 866 >SPBC23G7.08c |rga7||GTPase activating protein Rga7|Schizosaccharomyces pombe|chr 2|||Manual Length = 695 Score = 27.1 bits (57), Expect = 6.7 Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 366 NENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEPDPPKFPVFPNMVSVENDASQAKVSSG 425 N N ++P+ S P + +N + PA P + P+ + N +S + SS Sbjct: 369 NTNPAPSTFPNPSVASPAFPNSSTSNPSTAPASASPLASTLKPSTANDTNGSSSSS-SSN 427 Query: 426 AKTARP 431 +T+ P Sbjct: 428 PRTSSP 433 >SPBC365.20c ||SPBC557.06c|nicotinamidase |Schizosaccharomyces pombe|chr 2|||Manual Length = 220 Score = 27.1 bits (57), Expect = 6.7 Identities = 14/33 (42%), Positives = 18/33 (54%) Query: 345 TSVVAESQILLYKDWLLTSEVNENTPGKSYPDT 377 T V E+ +YK L S ENTPG +PD+ Sbjct: 75 TVVNIEAYGHVYKQTLWNSHCVENTPGCEFPDS 107 >SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 507 Score = 27.1 bits (57), Expect = 6.7 Identities = 15/51 (29%), Positives = 24/51 (47%), Gaps = 3/51 (5%) Query: 122 LTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ 172 L M+ + ++HRD+KP N ++ + T L DFG A +Q Sbjct: 200 LFQAMQQTQTLGIIHRDIKPSN---FLFDVRTKHGVLVDFGLAERYDGRQQ 247 >SPAC15A10.13 |ppk3||serine/threonine protein kinase Ppk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 637 Score = 26.6 bits (56), Expect = 8.8 Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 12/121 (9%) Query: 29 GVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIEEEQEGRGKVIV 88 G + + +P +V + + +H ++ R E +K ++H I+K L+ + + Sbjct: 39 GSIRESAQPCSVFSISLSTHPEWAELADRACETMKTLRHPCIIKYLSTYKSST-HLYIAT 97 Query: 89 MELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYI 148 + + N L TYGL ++A + L D N+VH +L+ ++ Y+ Sbjct: 98 ETVRPVTTELNELSAEIKTYGLW---------RVSAALSFLNDKNIVHGNLQMSSV--YL 146 Query: 149 N 149 N Sbjct: 147 N 147 >SPCC162.08c |nup211||nuclear pore complex associated protein|Schizosaccharomyces pombe|chr 3|||Manual Length = 1837 Score = 26.6 bits (56), Expect = 8.8 Identities = 21/82 (25%), Positives = 44/82 (53%), Gaps = 3/82 (3%) Query: 418 SQAKVSSGAKTARPALDRSMSSRRYKVAQTVYLQTQILDKDVSAAEIKLVALTERLQD-A 476 S ++ + A+ + + + S + A ++ Q L+K+VS+ E +L ERL+ Sbjct: 318 SNGELEKLLEAAQSSFEEQLESHKEAEA-SLKSQINFLEKEVSSLESQLKLANERLRHYD 376 Query: 477 ELKIRDAVSEAKNASKTSAAVK 498 E++I D +SE K ++ + ++K Sbjct: 377 EIEISD-MSELKYSNLLNNSMK 397 Database: spombe Posted date: Oct 3, 2007 3:31 PM Number of letters in database: 2,362,478 Number of sequences in database: 5004 Lambda K H 0.315 0.132 0.379 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 2,442,051 Number of Sequences: 5004 Number of extensions: 106098 Number of successful extensions: 561 Number of sequences better than 10.0: 115 Number of HSP's better than 10.0 without gapping: 78 Number of HSP's successfully gapped in prelim test: 37 Number of HSP's that attempted gapping in prelim test: 310 Number of HSP's gapped (non-prelim): 145 length of query: 543 length of database: 2,362,478 effective HSP length: 76 effective length of query: 467 effective length of database: 1,982,174 effective search space: 925675258 effective search space used: 925675258 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.6 bits) S2: 56 (26.6 bits)
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