Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000198-TA|BGIBMGA000198-PA|IPR000719|Protein kinase,
IPR011009|Protein kinase-like, IPR002290|Serine/threonine protein
kinase
(543 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF191838-1|AAF05989.1| 729|Homo sapiens TANK binding kinase TBK... 440 e-123
AF174536-1|AAF69106.1| 729|Homo sapiens NF-kB-activating kinase... 440 e-123
BC034950-1|AAH34950.1| 729|Homo sapiens TANK-binding kinase 1 p... 438 e-122
D63485-1|BAA09772.2| 723|Homo sapiens KIAA0151 protein. 427 e-119
DQ667176-1|ABG25921.1| 716|Homo sapiens inhibitor of kappa ligh... 427 e-119
BC105923-1|AAI05924.1| 716|Homo sapiens inhibitor of kappa ligh... 427 e-119
AL354681-1|CAI15250.1| 716|Homo sapiens inhibitor of kappa ligh... 427 e-119
AF241789-1|AAF45307.1| 716|Homo sapiens IKK epsilon protein. 427 e-119
AB016590-1|BAA85155.1| 716|Homo sapiens inducible IkappaB kinas... 427 e-119
BC105924-1|AAI05925.1| 716|Homo sapiens IKK-related kinase epsi... 426 e-118
BC107812-1|AAI07813.1| 631|Homo sapiens IKBKE protein protein. 330 1e-89
AY652653-1|AAT49098.1| 745|Homo sapiens conserved helix-loop-he... 121 7e-27
AF080157-1|AAD08996.1| 745|Homo sapiens IkB kinase-a protein. 121 7e-27
AF012890-1|AAC51662.1| 745|Homo sapiens IKK-a kinase protein. 121 7e-27
AF009225-1|AAC51671.1| 745|Homo sapiens IkB kinase alpha subuni... 121 7e-27
BC108694-1|AAI08695.1| 420|Homo sapiens IKBKB protein protein. 120 1e-26
AY663108-1|AAT65965.1| 756|Homo sapiens inhibitor of kappa ligh... 120 1e-26
AL138921-4|CAH72401.1| 745|Homo sapiens conserved helix-loop-he... 120 1e-26
AF080158-1|AAD08997.1| 756|Homo sapiens IkB kinase-b protein. 120 1e-26
AF029684-1|AAC51860.1| 756|Homo sapiens IkB kinase-beta protein. 120 1e-26
AB209028-1|BAD92265.1| 726|Homo sapiens conserved helix-loop-he... 120 1e-26
AF031416-1|AAC64675.1| 756|Homo sapiens IkB kinase beta subunit... 119 2e-26
BC092514-1|AAH92514.1| 745|Homo sapiens conserved helix-loop-he... 117 1e-25
BC006231-1|AAH06231.1| 256|Homo sapiens IKBKB protein protein. 116 2e-25
U22512-1|AAC50713.1| 714|Homo sapiens CHUK protein. 115 4e-25
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 103 1e-21
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 103 1e-21
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 103 1e-21
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 103 1e-21
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 102 3e-21
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 102 3e-21
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 102 3e-21
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 102 3e-21
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 102 3e-21
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 100 1e-20
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 100 1e-20
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 100 1e-20
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 100 1e-20
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 100 1e-20
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 100 1e-20
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 100 1e-20
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 100 1e-20
AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kina... 100 1e-20
AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinas... 99 3e-20
AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinas... 99 3e-20
AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinas... 99 3e-20
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 98 6e-20
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 98 6e-20
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 98 8e-20
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 98 8e-20
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 98 8e-20
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 98 8e-20
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 97 1e-19
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 97 1e-19
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 97 1e-19
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 97 1e-19
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 97 1e-19
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 97 1e-19
AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 97 1e-19
AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 97 1e-19
AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 97 1e-19
AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 97 1e-19
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 97 1e-19
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 97 1e-19
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 97 2e-19
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 97 2e-19
AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA seq... 97 2e-19
AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA seq... 97 2e-19
AB209090-1|BAD92327.1| 483|Homo sapiens inhibitor of kappa ligh... 97 2e-19
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 97 2e-19
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 96 3e-19
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 95 4e-19
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 95 4e-19
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 95 6e-19
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 95 6e-19
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 95 6e-19
BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein. 95 6e-19
BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein. 95 6e-19
BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein. 95 6e-19
AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein. 95 6e-19
AL713896-5|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 95 6e-19
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 95 6e-19
AL713896-3|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 95 6e-19
AL713896-2|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 95 6e-19
AL596247-5|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 95 6e-19
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 95 6e-19
AL596247-3|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 95 6e-19
AL596247-2|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 95 6e-19
AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein. 95 6e-19
AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein. 95 6e-19
AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein. 95 6e-19
AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein. 95 6e-19
AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein. 95 6e-19
AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein. 95 6e-19
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 95 6e-19
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 95 6e-19
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 94 1e-18
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 94 1e-18
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 94 1e-18
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 94 1e-18
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 94 1e-18
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 94 1e-18
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 94 1e-18
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 94 1e-18
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 94 1e-18
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 94 1e-18
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 94 1e-18
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 94 1e-18
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 93 2e-18
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 93 2e-18
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 93 2e-18
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 93 2e-18
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 93 2e-18
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 93 2e-18
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 93 2e-18
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 93 3e-18
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 93 3e-18
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 93 3e-18
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 93 3e-18
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 92 4e-18
BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein. 92 4e-18
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 92 4e-18
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 92 4e-18
AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein. 92 4e-18
AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase... 92 4e-18
U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase ... 92 5e-18
D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulati... 92 5e-18
BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated prote... 92 5e-18
BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated prote... 92 5e-18
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 92 5e-18
AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated prote... 92 5e-18
AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated prote... 92 5e-18
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 92 5e-18
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 92 5e-18
AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated prote... 92 5e-18
BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H... 91 7e-18
BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H... 91 7e-18
AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase... 91 7e-18
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 91 7e-18
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 91 7e-18
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 91 9e-18
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 91 9e-18
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 91 9e-18
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 91 9e-18
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 91 9e-18
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 91 9e-18
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 91 9e-18
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 91 9e-18
D86968-1|BAA13204.2| 1626|Homo sapiens KIAA0213 protein. 91 1e-17
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 91 1e-17
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 91 1e-17
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 91 1e-17
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 91 1e-17
AF002715-1|AAB68804.1| 1607|Homo sapiens MAP kinase kinase kinas... 91 1e-17
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 91 1e-17
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 90 2e-17
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 90 2e-17
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 90 2e-17
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 90 2e-17
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 90 2e-17
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 90 2e-17
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 90 2e-17
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 90 2e-17
BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase... 90 2e-17
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 90 2e-17
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 90 2e-17
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 90 2e-17
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 90 2e-17
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 90 2e-17
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 90 2e-17
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 90 2e-17
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 90 2e-17
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 90 2e-17
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 90 2e-17
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 90 2e-17
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 90 2e-17
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 90 2e-17
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 90 2e-17
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 90 2e-17
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 90 2e-17
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 90 2e-17
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 90 2e-17
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 90 2e-17
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 90 2e-17
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 90 2e-17
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 90 2e-17
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 90 2e-17
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 90 2e-17
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 90 2e-17
AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein. 90 2e-17
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 89 3e-17
D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein. 89 3e-17
BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase, g... 89 3e-17
BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase, g... 89 3e-17
BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase, g... 89 3e-17
BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase, g... 89 3e-17
BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing s... 89 3e-17
BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase, g... 89 3e-17
BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein. 89 3e-17
AL732423-2|CAM17479.1| 748|Homo sapiens mitogen-activated prote... 89 3e-17
AL732423-1|CAM17478.1| 788|Homo sapiens mitogen-activated prote... 89 3e-17
AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated prote... 89 3e-17
AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated prote... 89 3e-17
AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens ... 89 3e-17
AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein. 89 3e-17
AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase ga... 89 3e-17
AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein. 89 3e-17
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 89 4e-17
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 89 5e-17
U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein ... 89 5e-17
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 89 5e-17
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 89 5e-17
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 89 5e-17
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 89 5e-17
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 89 5e-17
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 89 5e-17
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 89 5e-17
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 89 5e-17
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 89 5e-17
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 89 5e-17
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 89 5e-17
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 89 5e-17
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 89 5e-17
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 89 5e-17
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 89 5e-17
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 89 5e-17
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 89 5e-17
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 89 5e-17
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 89 5e-17
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 89 5e-17
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 89 5e-17
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 89 5e-17
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 89 5e-17
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 89 5e-17
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 89 5e-17
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 89 5e-17
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 89 5e-17
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 89 5e-17
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 89 5e-17
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 89 5e-17
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 88 6e-17
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 88 6e-17
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 88 6e-17
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 88 6e-17
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 88 6e-17
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 88 6e-17
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 88 6e-17
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 88 6e-17
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 88 6e-17
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 88 9e-17
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 88 9e-17
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 88 9e-17
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 88 9e-17
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 88 9e-17
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 88 9e-17
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 88 9e-17
BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kina... 87 1e-16
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 87 1e-16
BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kina... 87 1e-16
BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light c... 87 1e-16
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 87 1e-16
AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kin... 87 1e-16
AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specifi... 87 1e-16
AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light c... 87 1e-16
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 87 1e-16
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 87 1e-16
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 87 1e-16
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 87 1e-16
AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens ... 87 1e-16
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 87 1e-16
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 87 2e-16
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 87 2e-16
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 87 2e-16
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 87 2e-16
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 87 2e-16
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 87 2e-16
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 87 2e-16
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 87 2e-16
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 87 2e-16
AL596452-3|CAI41309.1| 1498|Homo sapiens mitogen-activated prote... 86 3e-16
AL596452-2|CAI41310.1| 1544|Homo sapiens mitogen-activated prote... 86 3e-16
AL591045-2|CAH70639.1| 1498|Homo sapiens mitogen-activated prote... 86 3e-16
AL591045-1|CAH70640.1| 1544|Homo sapiens mitogen-activated prote... 86 3e-16
AL139393-2|CAI20815.1| 1498|Homo sapiens mitogen-activated prote... 86 3e-16
AL139393-1|CAI20816.1| 1544|Homo sapiens mitogen-activated prote... 86 3e-16
AL109942-4|CAI21477.1| 1498|Homo sapiens mitogen-activated prote... 86 3e-16
AL109942-3|CAC12766.2| 1544|Homo sapiens mitogen-activated prote... 86 3e-16
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 86 3e-16
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 86 3e-16
AL117326-3|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 86 3e-16
AL117326-2|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 86 3e-16
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 86 3e-16
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 86 3e-16
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 86 3e-16
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 86 3e-16
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 86 3e-16
U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein ... 85 5e-16
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 85 5e-16
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 85 5e-16
BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein. 85 5e-16
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 85 5e-16
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 85 5e-16
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 85 5e-16
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 85 5e-16
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 85 5e-16
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 85 5e-16
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 85 5e-16
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 85 5e-16
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 85 5e-16
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 85 5e-16
AK055778-1|BAB71011.1| 1113|Homo sapiens protein ( Homo sapiens ... 85 5e-16
AF391558-1|AAO13803.1| 1192|Homo sapiens myosin IIIB variant MYO... 85 5e-16
AF391557-1|AAO13802.1| 1275|Homo sapiens myosin IIIB variant MYO... 85 5e-16
AF391556-1|AAO13801.1| 1314|Homo sapiens myosin IIIB variant MYO... 85 5e-16
AF391555-1|AAO13800.1| 1341|Homo sapiens myosin IIIB variant MYO... 85 5e-16
AF391554-1|AAO13799.1| 1251|Homo sapiens myosin IIIB variant MYO... 85 5e-16
AF369908-1|AAL57233.1| 1278|Homo sapiens myosin IIIB protein. 85 5e-16
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 85 5e-16
AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase p... 85 5e-16
AC114794-1|AAY24159.1| 249|Homo sapiens unknown protein. 85 5e-16
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 85 5e-16
U63973-1|AAB05929.1| 563|Homo sapiens rhodopsin kinase protein. 85 6e-16
L77503-1|AAG50439.1| 563|Homo sapiens rhodopsin kinase protein. 85 6e-16
L77502-1|AAT00534.2| 563|Homo sapiens rhodopsin kinase protein. 85 6e-16
BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein. 85 6e-16
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 85 8e-16
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 85 8e-16
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 85 8e-16
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 85 8e-16
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 85 8e-16
AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent kinase... 85 8e-16
AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent kinase... 85 8e-16
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 85 8e-16
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 84 1e-15
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 84 1e-15
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 84 1e-15
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 84 1e-15
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 84 1e-15
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 84 1e-15
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 84 1e-15
AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing ... 84 1e-15
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 83 2e-15
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 83 2e-15
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 83 2e-15
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 83 2e-15
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 83 2e-15
CR542225-1|CAG47021.1| 372|Homo sapiens STK17B protein. 83 2e-15
BC035807-1|AAH35807.1| 292|Homo sapiens ICK protein protein. 83 2e-15
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 83 3e-15
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 83 3e-15
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 83 3e-15
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 83 3e-15
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 83 3e-15
CR542210-1|CAG47006.1| 372|Homo sapiens STK17B protein. 83 3e-15
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 83 3e-15
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 83 3e-15
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 83 3e-15
BC016040-1|AAH16040.1| 372|Homo sapiens serine/threonine kinase... 83 3e-15
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 83 3e-15
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 83 3e-15
AY098866-1|AAM21719.1| 486|Homo sapiens PKE protein kinase prot... 83 3e-15
AL590105-1|CAI13011.1| 486|Homo sapiens protein kinase (PKE) pr... 83 3e-15
AL512622-1|CAI12181.1| 486|Homo sapiens protein kinase (PKE) pr... 83 3e-15
AL358612-2|CAH73815.1| 197|Homo sapiens myosin IIIA protein. 83 3e-15
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 83 3e-15
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 83 3e-15
AC114760-2|AAY14982.1| 372|Homo sapiens unknown protein. 83 3e-15
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 83 3e-15
AB011421-1|BAA34127.1| 372|Homo sapiens DRAK2 protein. 83 3e-15
AL023754-2|CAI19990.1| 245|Homo sapiens calcium/calmodulin-depe... 82 4e-15
AF099989-1|AAC72238.1| 547|Homo sapiens Ste-20 related kinase S... 82 4e-15
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 82 4e-15
AC067940-1|AAY24032.1| 363|Homo sapiens unknown protein. 82 4e-15
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 82 4e-15
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 82 6e-15
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 82 6e-15
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 82 6e-15
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 82 6e-15
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 82 6e-15
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 82 6e-15
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 82 6e-15
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 82 6e-15
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 82 6e-15
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 82 6e-15
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 82 6e-15
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 82 6e-15
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 82 6e-15
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 82 6e-15
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 82 6e-15
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 82 6e-15
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 82 6e-15
AF439409-1|AAL48216.1| 553|Homo sapiens G-protein-coupled recep... 82 6e-15
AF282269-1|AAL33880.1| 553|Homo sapiens G protein-coupled recep... 82 6e-15
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 82 6e-15
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 82 6e-15
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 81 7e-15
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 81 7e-15
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 81 1e-14
BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein. 81 1e-14
BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein. 81 1e-14
BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for IM... 81 1e-14
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 81 1e-14
AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein. 81 1e-14
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 81 1e-14
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 81 1e-14
AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-depende... 81 1e-14
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 81 1e-14
AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived STE20-... 81 1e-14
AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein. 81 1e-14
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 81 1e-14
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 81 1e-14
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 81 1e-14
AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kina... 81 1e-14
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 81 1e-14
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 81 1e-14
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 80 2e-14
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 80 2e-14
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 80 2e-14
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 80 2e-14
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 80 2e-14
U12779-1|AAA20851.1| 370|Homo sapiens MAP kinase activated prot... 80 2e-14
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 80 2e-14
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 80 2e-14
BC052584-1|AAH52584.1| 400|Homo sapiens mitogen-activated prote... 80 2e-14
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 80 2e-14
BC036060-1|AAH36060.2| 400|Homo sapiens mitogen-activated prote... 80 2e-14
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 80 2e-14
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 80 2e-14
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 80 2e-14
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 80 2e-14
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 80 2e-14
AL591846-12|CAI13544.1| 400|Homo sapiens mitogen-activated prot... 80 2e-14
AL591846-11|CAI13543.1| 370|Homo sapiens mitogen-activated prot... 80 2e-14
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 80 2e-14
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 80 2e-14
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 80 2e-14
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 80 2e-14
AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens ... 80 2e-14
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 80 2e-14
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 80 2e-14
AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b p... 80 2e-14
AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein. 80 2e-14
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 80 2e-14
AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b v... 80 2e-14
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 80 2e-14
BC026060-1|AAH26060.1| 541|Homo sapiens calcium/calmodulin-depe... 80 2e-14
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 80 2e-14
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 80 2e-14
AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-depende... 80 2e-14
AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-depende... 80 2e-14
AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform pr... 80 2e-14
AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform pr... 80 2e-14
AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform pr... 80 2e-14
AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform pr... 80 2e-14
AF287631-1|AAK64601.1| 533|Homo sapiens calcium/calmodulin-depe... 80 2e-14
AF287630-1|AAK64600.1| 588|Homo sapiens calcium/calmodulin-depe... 80 2e-14
AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-depende... 80 2e-14
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 80 2e-14
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 80 2e-14
AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-depende... 80 2e-14
AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-depende... 80 2e-14
AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein. 80 2e-14
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 80 2e-14
U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein ... 79 3e-14
U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein. 79 3e-14
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 79 3e-14
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 79 3e-14
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 79 3e-14
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 79 3e-14
BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase... 79 3e-14
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 79 3e-14
AL162581-2|CAI19518.1| 632|Homo sapiens RP1-132F22.1 protein. 79 3e-14
AL031178-1|CAI20261.1| 632|Homo sapiens RP1-132F22.1 protein. 79 3e-14
AJ250839-1|CAB76471.1| 414|Homo sapiens serine/threonine protei... 79 3e-14
AF152469-1|AAG43364.1| 632|Homo sapiens MAK-related kinase prot... 79 3e-14
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 79 3e-14
AB023153-1|BAA76780.2| 640|Homo sapiens KIAA0936 protein protein. 79 3e-14
DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress respon... 79 4e-14
BC117311-1|AAI17312.1| 898|Homo sapiens CASK protein protein. 79 4e-14
BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein. 79 4e-14
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 79 4e-14
BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress respon... 79 4e-14
AY705392-1|AAU10527.1| 921|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL627402-6|CAH71241.1| 590|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL627402-5|CAH71238.1| 897|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL627402-4|CAH71237.1| 909|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL627402-3|CAH71240.1| 926|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL627402-2|CAH71239.1| 921|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL603754-6|CAI41638.1| 590|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL603754-5|CAI41635.1| 926|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL603754-4|CAI41636.1| 921|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL603754-3|CAI41637.1| 897|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL603754-2|CAI41634.1| 909|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL445239-7|CAI41096.1| 590|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL445239-6|CAI41093.1| 926|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL445239-5|CAI41094.1| 921|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL445239-4|CAI41095.1| 897|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL445239-3|CAI41092.1| 909|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL353691-7|CAI42248.1| 590|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL353691-6|CAI42245.1| 926|Homo sapiens calcium/calmodulin-depe... 79 4e-14
>AF191838-1|AAF05989.1| 729|Homo sapiens TANK binding kinase TBK1
protein.
Length = 729
Score = 440 bits (1084), Expect = e-123
Identities = 214/425 (50%), Positives = 288/425 (67%), Gaps = 8/425 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + N++W + +LG+GAT VF+G +K G+ A+K FN +S +RP DVQMREFEVLK
Sbjct: 1 MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK 60
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL AIEEE R KV++ME C GSL+ +L++P N YGL E EFL+VL +
Sbjct: 61 KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV 120
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
GM HLR+N +VHRD+KPGNIM+ I EDG + YKLTDFGAAREL+++EQFVSLYGTEEYL
Sbjct: 121 GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL 180
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPY-GGRRNKETMFYITTK 242
HPDMYERAVLRK K +GATVDLWSIGVT YH ATG LPFRP+ G RRNKE M+ I T
Sbjct: 181 HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG 240
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFS 302
K SG ISG Q ENGPIDW+ ++P C LS GL+ L+TP+LA +LE D + W F++FF+
Sbjct: 241 KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA 300
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLT 362
E + +HVF + + T+ K+++ H V +QT +++ +Q L+Y+ L
Sbjct: 301 ETSDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLV 360
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKNN-NNVSMPAEP-DPPKFPVFPNMVSVENDASQA 420
E + +P T+ + P+ + ++ N + + E PK V P ++ DAS A
Sbjct: 361 LE--PGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPK--VHPR-YDLDGDASMA 415
Query: 421 KVSSG 425
K +G
Sbjct: 416 KAITG 420
>AF174536-1|AAF69106.1| 729|Homo sapiens NF-kB-activating kinase
NAK protein.
Length = 729
Score = 440 bits (1084), Expect = e-123
Identities = 214/425 (50%), Positives = 288/425 (67%), Gaps = 8/425 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + N++W + +LG+GAT VF+G +K G+ A+K FN +S +RP DVQMREFEVLK
Sbjct: 1 MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK 60
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL AIEEE R KV++ME C GSL+ +L++P N YGL E EFL+VL +
Sbjct: 61 KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV 120
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
GM HLR+N +VHRD+KPGNIM+ I EDG + YKLTDFGAAREL+++EQFVSLYGTEEYL
Sbjct: 121 GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL 180
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPY-GGRRNKETMFYITTK 242
HPDMYERAVLRK K +GATVDLWSIGVT YH ATG LPFRP+ G RRNKE M+ I T
Sbjct: 181 HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG 240
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFS 302
K SG ISG Q ENGPIDW+ ++P C LS GL+ L+TP+LA +LE D + W F++FF+
Sbjct: 241 KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA 300
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLT 362
E + +HVF + + T+ K+++ H V +QT +++ +Q L+Y+ L
Sbjct: 301 ETSDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLV 360
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKNN-NNVSMPAEP-DPPKFPVFPNMVSVENDASQA 420
E + +P T+ + P+ + ++ N + + E PK V P ++ DAS A
Sbjct: 361 LE--PGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPK--VHPR-YDLDGDASMA 415
Query: 421 KVSSG 425
K +G
Sbjct: 416 KAITG 420
>BC034950-1|AAH34950.1| 729|Homo sapiens TANK-binding kinase 1
protein.
Length = 729
Score = 438 bits (1079), Expect = e-122
Identities = 213/425 (50%), Positives = 288/425 (67%), Gaps = 8/425 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + N++W + +LG+GAT VF+G +K G+ A+K FN +S +RP DVQMREFEVLK
Sbjct: 1 MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK 60
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL AIEEE R KV++ME C GSL+ +L++P N YGL E EFL+VL +
Sbjct: 61 KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV 120
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
GM HLR+N +VHRD+KPGNIM+ I EDG + YKLTDFGAAREL+++EQFVSLYGTEEYL
Sbjct: 121 GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL 180
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPY-GGRRNKETMFYITTK 242
HPDMYERAVLRK K +GATVDLWSIGVT YH ATG LPFRP+ G RRNKE M+ I T
Sbjct: 181 HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG 240
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFS 302
K SG ISG Q ENGPIDW+ ++P C LS GL+ L+TP+LA +LE D + W F++FF+
Sbjct: 241 KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA 300
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLT 362
E + +HVF + + T+ K+++ H V +QT +++ +Q L+Y+ L
Sbjct: 301 ETSDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLV 360
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKNN-NNVSMPAEP-DPPKFPVFPNMVSVENDASQA 420
E + +P T+ + P+ + ++ + + + E PK V P ++ DAS A
Sbjct: 361 LE--PGRLAQHFPKTTEENPIFVVSREPLDTIGLIYEKISLPK--VHPR-YDLDGDASMA 415
Query: 421 KVSSG 425
K +G
Sbjct: 416 KAITG 420
>D63485-1|BAA09772.2| 723|Homo sapiens KIAA0151 protein.
Length = 723
Score = 427 bits (1053), Expect = e-119
Identities = 213/426 (50%), Positives = 287/426 (67%), Gaps = 8/426 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + NY+W T +LG+GAT +V++ NK +GE VAVK FN S++RP +VQ+REFEVL+
Sbjct: 8 MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR 67
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL A+EE R KV+VME C+ GSL ++L+ PEN +GL E EFL+VL +
Sbjct: 68 KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV 127
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
AGM HLR+N +VHRD+KPGNIM+ + E+G + YKLTDFGAAREL ++E+FVS+YGTEEYL
Sbjct: 128 AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL 187
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGG-RRNKETMFYITTK 242
HPDMYERAVLRKP K+FG TVDLWSIGVTLYH ATG LPF P+GG RRNKE M+ ITT+
Sbjct: 188 HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE 247
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFS 302
K +G I+G Q ENGP++W+ LP CQLS+GL+ + P+LA +LEV+ + W F++FF+
Sbjct: 248 KPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFA 307
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLT 362
E + VHVF +++A +++ V +QTSV Q L++ L
Sbjct: 308 ETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCV 367
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEP--DPPKFPVFPNMVSVENDASQA 420
E + + T+A PL LF+ +P D PKF P V ++ D + A
Sbjct: 368 LE--PSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKF--VPK-VDLQADYNTA 422
Query: 421 KVSSGA 426
K GA
Sbjct: 423 KGVLGA 428
>DQ667176-1|ABG25921.1| 716|Homo sapiens inhibitor of kappa light
polypeptide gene enhancer in B-cells, kinase epsilon
protein.
Length = 716
Score = 427 bits (1053), Expect = e-119
Identities = 213/426 (50%), Positives = 287/426 (67%), Gaps = 8/426 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + NY+W T +LG+GAT +V++ NK +GE VAVK FN S++RP +VQ+REFEVL+
Sbjct: 1 MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR 60
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL A+EE R KV+VME C+ GSL ++L+ PEN +GL E EFL+VL +
Sbjct: 61 KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV 120
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
AGM HLR+N +VHRD+KPGNIM+ + E+G + YKLTDFGAAREL ++E+FVS+YGTEEYL
Sbjct: 121 AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL 180
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGG-RRNKETMFYITTK 242
HPDMYERAVLRKP K+FG TVDLWSIGVTLYH ATG LPF P+GG RRNKE M+ ITT+
Sbjct: 181 HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE 240
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFS 302
K +G I+G Q ENGP++W+ LP CQLS+GL+ + P+LA +LEV+ + W F++FF+
Sbjct: 241 KPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFA 300
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLT 362
E + VHVF +++A +++ V +QTSV Q L++ L
Sbjct: 301 ETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCV 360
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEP--DPPKFPVFPNMVSVENDASQA 420
E + + T+A PL LF+ +P D PKF P V ++ D + A
Sbjct: 361 LE--PSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKF--VPK-VDLQADYNTA 415
Query: 421 KVSSGA 426
K GA
Sbjct: 416 KGVLGA 421
>BC105923-1|AAI05924.1| 716|Homo sapiens inhibitor of kappa light
polypeptide gene enhancer in B-cells, kinase epsilon
protein.
Length = 716
Score = 427 bits (1053), Expect = e-119
Identities = 213/426 (50%), Positives = 287/426 (67%), Gaps = 8/426 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + NY+W T +LG+GAT +V++ NK +GE VAVK FN S++RP +VQ+REFEVL+
Sbjct: 1 MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR 60
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL A+EE R KV+VME C+ GSL ++L+ PEN +GL E EFL+VL +
Sbjct: 61 KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV 120
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
AGM HLR+N +VHRD+KPGNIM+ + E+G + YKLTDFGAAREL ++E+FVS+YGTEEYL
Sbjct: 121 AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL 180
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGG-RRNKETMFYITTK 242
HPDMYERAVLRKP K+FG TVDLWSIGVTLYH ATG LPF P+GG RRNKE M+ ITT+
Sbjct: 181 HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE 240
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFS 302
K +G I+G Q ENGP++W+ LP CQLS+GL+ + P+LA +LEV+ + W F++FF+
Sbjct: 241 KPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFA 300
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLT 362
E + VHVF +++A +++ V +QTSV Q L++ L
Sbjct: 301 ETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCV 360
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEP--DPPKFPVFPNMVSVENDASQA 420
E + + T+A PL LF+ +P D PKF P V ++ D + A
Sbjct: 361 LE--PSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKF--VPK-VDLQADYNTA 415
Query: 421 KVSSGA 426
K GA
Sbjct: 416 KGVLGA 421
>AL354681-1|CAI15250.1| 716|Homo sapiens inhibitor of kappa light
polypeptide gene enhancer in B-cells, kinase epsilon
protein.
Length = 716
Score = 427 bits (1053), Expect = e-119
Identities = 213/426 (50%), Positives = 287/426 (67%), Gaps = 8/426 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + NY+W T +LG+GAT +V++ NK +GE VAVK FN S++RP +VQ+REFEVL+
Sbjct: 1 MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR 60
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL A+EE R KV+VME C+ GSL ++L+ PEN +GL E EFL+VL +
Sbjct: 61 KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV 120
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
AGM HLR+N +VHRD+KPGNIM+ + E+G + YKLTDFGAAREL ++E+FVS+YGTEEYL
Sbjct: 121 AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL 180
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGG-RRNKETMFYITTK 242
HPDMYERAVLRKP K+FG TVDLWSIGVTLYH ATG LPF P+GG RRNKE M+ ITT+
Sbjct: 181 HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE 240
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFS 302
K +G I+G Q ENGP++W+ LP CQLS+GL+ + P+LA +LEV+ + W F++FF+
Sbjct: 241 KPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFA 300
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLT 362
E + VHVF +++A +++ V +QTSV Q L++ L
Sbjct: 301 ETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCV 360
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEP--DPPKFPVFPNMVSVENDASQA 420
E + + T+A PL LF+ +P D PKF P V ++ D + A
Sbjct: 361 LE--PSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKF--VPK-VDLQADYNTA 415
Query: 421 KVSSGA 426
K GA
Sbjct: 416 KGVLGA 421
>AF241789-1|AAF45307.1| 716|Homo sapiens IKK epsilon protein.
Length = 716
Score = 427 bits (1053), Expect = e-119
Identities = 213/426 (50%), Positives = 287/426 (67%), Gaps = 8/426 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + NY+W T +LG+GAT +V++ NK +GE VAVK FN S++RP +VQ+REFEVL+
Sbjct: 1 MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR 60
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL A+EE R KV+VME C+ GSL ++L+ PEN +GL E EFL+VL +
Sbjct: 61 KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV 120
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
AGM HLR+N +VHRD+KPGNIM+ + E+G + YKLTDFGAAREL ++E+FVS+YGTEEYL
Sbjct: 121 AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL 180
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGG-RRNKETMFYITTK 242
HPDMYERAVLRKP K+FG TVDLWSIGVTLYH ATG LPF P+GG RRNKE M+ ITT+
Sbjct: 181 HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE 240
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFS 302
K +G I+G Q ENGP++W+ LP CQLS+GL+ + P+LA +LEV+ + W F++FF+
Sbjct: 241 KPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFA 300
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLT 362
E + VHVF +++A +++ V +QTSV Q L++ L
Sbjct: 301 ETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCV 360
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEP--DPPKFPVFPNMVSVENDASQA 420
E + + T+A PL LF+ +P D PKF P V ++ D + A
Sbjct: 361 LE--PSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKF--VPK-VDLQADYNTA 415
Query: 421 KVSSGA 426
K GA
Sbjct: 416 KGVLGA 421
>AB016590-1|BAA85155.1| 716|Homo sapiens inducible IkappaB kinase
protein.
Length = 716
Score = 427 bits (1053), Expect = e-119
Identities = 213/426 (50%), Positives = 287/426 (67%), Gaps = 8/426 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + NY+W T +LG+GAT +V++ NK +GE VAVK FN S++RP +VQ+REFEVL+
Sbjct: 1 MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR 60
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL A+EE R KV+VME C+ GSL ++L+ PEN +GL E EFL+VL +
Sbjct: 61 KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV 120
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
AGM HLR+N +VHRD+KPGNIM+ + E+G + YKLTDFGAAREL ++E+FVS+YGTEEYL
Sbjct: 121 AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL 180
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGG-RRNKETMFYITTK 242
HPDMYERAVLRKP K+FG TVDLWSIGVTLYH ATG LPF P+GG RRNKE M+ ITT+
Sbjct: 181 HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE 240
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFS 302
K +G I+G Q ENGP++W+ LP CQLS+GL+ + P+LA +LEV+ + W F++FF+
Sbjct: 241 KPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFA 300
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLT 362
E + VHVF +++A +++ V +QTSV Q L++ L
Sbjct: 301 ETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCV 360
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEP--DPPKFPVFPNMVSVENDASQA 420
E + + T+A PL LF+ +P D PKF P V ++ D + A
Sbjct: 361 LE--PSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKF--VPK-VDLQADYNTA 415
Query: 421 KVSSGA 426
K GA
Sbjct: 416 KGVLGA 421
>BC105924-1|AAI05925.1| 716|Homo sapiens IKK-related kinase epsilon
protein.
Length = 716
Score = 426 bits (1049), Expect = e-118
Identities = 212/426 (49%), Positives = 287/426 (67%), Gaps = 8/426 (1%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
++ + NY+W T +LG+GAT +V++ NK +GE VAVK FN S++RP +VQ+REFEVL+
Sbjct: 1 MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR 60
Query: 64 KVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLT 123
K+ H+NIVKL A+EE R KV+VME C+ GSL ++L+ PEN +GL E EFL+VL +
Sbjct: 61 KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV 120
Query: 124 AGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYL 183
AGM HLR+N +VHRD+KPGNIM+ + E+G + YKLTDFGAAREL ++E+FVS+YGTEEYL
Sbjct: 121 AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL 180
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGG-RRNKETMFYITTK 242
HPDMYE+AVLRKP K+FG TVDLWSIGVTLYH ATG LPF P+GG RRNKE M+ ITT+
Sbjct: 181 HPDMYEQAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE 240
Query: 243 KASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFS 302
K +G I+G Q ENGP++W+ LP CQLS+GL+ + P+LA +LEV+ + W F++FF+
Sbjct: 241 KPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFA 300
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLT 362
E + VHVF +++A +++ V +QTSV Q L++ L
Sbjct: 301 ETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCV 360
Query: 363 SEVNENTPGKSYPDTSADEPLLLFNKNNNNVSMPAEP--DPPKFPVFPNMVSVENDASQA 420
E + + T+A PL LF+ +P D PKF P V ++ D + A
Sbjct: 361 LE--PSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKF--VPK-VDLQADYNTA 415
Query: 421 KVSSGA 426
K GA
Sbjct: 416 KGVLGA 421
>BC107812-1|AAI07813.1| 631|Homo sapiens IKBKE protein protein.
Length = 631
Score = 330 bits (810), Expect = 1e-89
Identities = 168/341 (49%), Positives = 223/341 (65%), Gaps = 8/341 (2%)
Query: 89 MELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYI 148
ME C+ GSL ++L+ PEN +GL E EFL+VL + AGM HLR+N +VHRD+KPGNIM+ +
Sbjct: 1 MEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVVAGMNHLRENGIVHRDIKPGNIMRLV 60
Query: 149 NEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLW 208
E+G + YKLTDFGAAREL ++E+FVS+YGTEEYLHPDMYERAVLRKP K+FG TVDLW
Sbjct: 61 GEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYLHPDMYERAVLRKPQQKAFGVTVDLW 120
Query: 209 SIGVTLYHVATGQLPFRPYGG-RRNKETMFYITTKKASGVISGTQTTENGPIDWARELPP 267
SIGVTLYH ATG LPF P+GG RRNKE M+ ITT+K +G I+G Q ENGP++W+ LP
Sbjct: 121 SIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTEKPAGAIAGAQRRENGPLEWSYTLPI 180
Query: 268 HCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERFFSEVQVVTSTKPVHVFYVNKATSIKVF 327
CQLS+GL+ + P+LA +LEV+ + W F++FF+E + VHVF +++A ++
Sbjct: 181 TCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFAETSDILQRVVVHVFSLSQAVLHHIY 240
Query: 328 LKLEEKYGHLHTYVCEQTSVVAESQILLYKDWLLTSEVNENTPGKSYPDTSADEPLLLFN 387
+ V +QTSV Q L++ L E + + T+A PL LF+
Sbjct: 241 IHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCVLE--PSVSAQHIAHTTASSPLTLFS 298
Query: 388 KNNNNVSMPAEP--DPPKFPVFPNMVSVENDASQAKVSSGA 426
+P D PKF P V ++ D + AK GA
Sbjct: 299 TAIPKGLAFRDPALDVPKF--VPK-VDLQADYNTAKGVLGA 336
>AY652653-1|AAT49098.1| 745|Homo sapiens conserved helix-loop-helix
ubiquitous kinase protein.
Length = 745
Score = 121 bits (291), Expect = 7e-27
Identities = 95/362 (26%), Positives = 161/362 (44%), Gaps = 23/362 (6%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
LR W LG G G V ++ +A+K+ + + E +++K
Sbjct: 7 LRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMK 66
Query: 64 KVKHENIVKLLAIEEEQE---GRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
K+ H N+VK + EE ++ ME C+GG L +L+ PEN GL+E + L +L
Sbjct: 67 KLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLS 126
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +G+++L +N ++HRDLKP NI+ + G +K+ D G A+++ + S GT
Sbjct: 127 DIGSGIRYLHENKIIHRDLKPENIVLQ-DVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTL 185
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
+YL P+++E K + ATVD WS G ++ G +RP+ T
Sbjct: 186 QYLAPELFE--------NKPYTATVDYWSFGTMVFECIAG---YRPFLHHLQPFTWHEKI 234
Query: 241 TKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHR------- 293
KK I + +G + ++ LP L + + + L +L DP +
Sbjct: 235 KKKDPKCIFACEEM-SGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRGGPVDL 293
Query: 294 IWTFERFFSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQI 353
R F + + + K VH+ + A I L +E L + + +T + SQ
Sbjct: 294 TLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQE 353
Query: 354 LL 355
LL
Sbjct: 354 LL 355
>AF080157-1|AAD08996.1| 745|Homo sapiens IkB kinase-a protein.
Length = 745
Score = 121 bits (291), Expect = 7e-27
Identities = 95/362 (26%), Positives = 161/362 (44%), Gaps = 23/362 (6%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
LR W LG G G V ++ +A+K+ + + E +++K
Sbjct: 7 LRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMK 66
Query: 64 KVKHENIVKLLAIEEEQE---GRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
K+ H N+VK + EE ++ ME C+GG L +L+ PEN GL+E + L +L
Sbjct: 67 KLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLS 126
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +G+++L +N ++HRDLKP NI+ + G +K+ D G A+++ + S GT
Sbjct: 127 DIGSGIRYLHENKIIHRDLKPENIVLQ-DVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTL 185
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
+YL P+++E K + ATVD WS G ++ G +RP+ T
Sbjct: 186 QYLAPELFE--------NKPYTATVDYWSFGTMVFECIAG---YRPFLHHLQPFTWHEKI 234
Query: 241 TKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHR------- 293
KK I + +G + ++ LP L + + + L +L DP +
Sbjct: 235 KKKDPKCIFACEEM-SGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRGGPVDL 293
Query: 294 IWTFERFFSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQI 353
R F + + + K VH+ + A I L +E L + + +T + SQ
Sbjct: 294 TLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQE 353
Query: 354 LL 355
LL
Sbjct: 354 LL 355
>AF012890-1|AAC51662.1| 745|Homo sapiens IKK-a kinase protein.
Length = 745
Score = 121 bits (291), Expect = 7e-27
Identities = 95/362 (26%), Positives = 161/362 (44%), Gaps = 23/362 (6%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
LR W LG G G V ++ +A+K+ + + E +++K
Sbjct: 7 LRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMK 66
Query: 64 KVKHENIVKLLAIEEEQE---GRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
K+ H N+VK + EE ++ ME C+GG L +L+ PEN GL+E + L +L
Sbjct: 67 KLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLS 126
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +G+++L +N ++HRDLKP NI+ + G +K+ D G A+++ + S GT
Sbjct: 127 DIGSGIRYLHENKIIHRDLKPENIVLQ-DVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTL 185
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
+YL P+++E K + ATVD WS G ++ G +RP+ T
Sbjct: 186 QYLAPELFE--------NKPYTATVDYWSFGTMVFECIAG---YRPFLHHLQPFTWHEKI 234
Query: 241 TKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHR------- 293
KK I + +G + ++ LP L + + + L +L DP +
Sbjct: 235 KKKDPKCIFACEEM-SGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRGGPVDL 293
Query: 294 IWTFERFFSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQI 353
R F + + + K VH+ + A I L +E L + + +T + SQ
Sbjct: 294 TLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQE 353
Query: 354 LL 355
LL
Sbjct: 354 LL 355
>AF009225-1|AAC51671.1| 745|Homo sapiens IkB kinase alpha subunit
protein.
Length = 745
Score = 121 bits (291), Expect = 7e-27
Identities = 95/362 (26%), Positives = 161/362 (44%), Gaps = 23/362 (6%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
LR W LG G G V ++ +A+K+ + + E +++K
Sbjct: 7 LRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMK 66
Query: 64 KVKHENIVKLLAIEEEQE---GRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
K+ H N+VK + EE ++ ME C+GG L +L+ PEN GL+E + L +L
Sbjct: 67 KLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLS 126
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +G+++L +N ++HRDLKP NI+ + G +K+ D G A+++ + S GT
Sbjct: 127 DIGSGIRYLHENKIIHRDLKPENIVLQ-DVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTL 185
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
+YL P+++E K + ATVD WS G ++ G +RP+ T
Sbjct: 186 QYLAPELFE--------NKPYTATVDYWSFGTMVFECIAG---YRPFLHHLQPFTWHEKI 234
Query: 241 TKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHR------- 293
KK I + +G + ++ LP L + + + L +L DP +
Sbjct: 235 KKKDPKCIFACEEM-SGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRGGPVDL 293
Query: 294 IWTFERFFSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQI 353
R F + + + K VH+ + A I L +E L + + +T + SQ
Sbjct: 294 TLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQE 353
Query: 354 LL 355
LL
Sbjct: 354 LL 355
>BC108694-1|AAI08695.1| 420|Homo sapiens IKBKB protein protein.
Length = 420
Score = 120 bits (290), Expect = 1e-26
Identities = 91/353 (25%), Positives = 154/353 (43%), Gaps = 22/353 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG G G V + N+ GE +A+K Q R + E ++++++ H N+V
Sbjct: 15 WEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVV 74
Query: 72 KLLAIEEEQEGRGK----VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
+ E + ++ ME C GG L L+ EN GL+E L +L + + ++
Sbjct: 75 AARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALR 134
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
+L +N ++HRDLKP NI+ E +K+ D G A+EL + S GT +YL P++
Sbjct: 135 YLHENRIIHRDLKPENIVLQQGEQ-RLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPEL 193
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGV 247
E+ + + TVD WS G + TG PF P + ++ ++ S V
Sbjct: 194 LEQ--------QKYTVTVDYWSFGTLAFECITGFRPFLP----NWQPVQWHSKVRQKSEV 241
Query: 248 ISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERF-----FS 302
NG + ++ LP L+ L + + L +L P + T + F
Sbjct: 242 DIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFK 301
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILL 355
+ + + K VH+ + T + +E L + + T + E Q LL
Sbjct: 302 ALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELL 354
>AY663108-1|AAT65965.1| 756|Homo sapiens inhibitor of kappa light
polypeptide gene enhancer in B-cells, kinase beta
protein.
Length = 756
Score = 120 bits (290), Expect = 1e-26
Identities = 91/353 (25%), Positives = 154/353 (43%), Gaps = 22/353 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG G G V + N+ GE +A+K Q R + E ++++++ H N+V
Sbjct: 15 WEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVV 74
Query: 72 KLLAIEEEQEGRGK----VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
+ E + ++ ME C GG L L+ EN GL+E L +L + + ++
Sbjct: 75 AARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALR 134
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
+L +N ++HRDLKP NI+ E +K+ D G A+EL + S GT +YL P++
Sbjct: 135 YLHENRIIHRDLKPENIVLQQGEQ-RLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPEL 193
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGV 247
E+ + + TVD WS G + TG PF P + ++ ++ S V
Sbjct: 194 LEQ--------QKYTVTVDYWSFGTLAFECITGFRPFLP----NWQPVQWHSKVRQKSEV 241
Query: 248 ISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERF-----FS 302
NG + ++ LP L+ L + + L +L P + T + F
Sbjct: 242 DIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFK 301
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILL 355
+ + + K VH+ + T + +E L + + T + E Q LL
Sbjct: 302 ALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELL 354
>AL138921-4|CAH72401.1| 745|Homo sapiens conserved helix-loop-helix
ubiquitous kinase protein.
Length = 745
Score = 120 bits (290), Expect = 1e-26
Identities = 95/362 (26%), Positives = 161/362 (44%), Gaps = 23/362 (6%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
LR W LG G G V ++ +A+K+ + + E +++K
Sbjct: 7 LRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMK 66
Query: 64 KVKHENIVKLLAIEEEQE---GRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
K+ H N+VK + EE ++ ME C+GG L +L+ PEN GL+E + L +L
Sbjct: 67 KLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLS 126
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +G+++L +N ++HRDLKP NI+ + G +K+ D G A+++ + S GT
Sbjct: 127 DIGSGIRYLHENKIIHRDLKPENIVLQ-DVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTL 185
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
+YL P+++E K + ATVD WS G ++ G +RP+ T
Sbjct: 186 QYLAPELFE--------NKPYTATVDYWSFGTMVFECIAG---YRPFLHHLQPFTWHEKI 234
Query: 241 TKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHR------- 293
KK I + +G + ++ LP L + + + L +L DP +
Sbjct: 235 KKKDPKCIFACEEM-SGEVRFSSHLPQPNSLCSLVVEPMENWLQLMLNWDPQQRGGPVDL 293
Query: 294 IWTFERFFSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQI 353
R F + + + K VH+ + A I L +E L + + +T + SQ
Sbjct: 294 TLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQE 353
Query: 354 LL 355
LL
Sbjct: 354 LL 355
>AF080158-1|AAD08997.1| 756|Homo sapiens IkB kinase-b protein.
Length = 756
Score = 120 bits (290), Expect = 1e-26
Identities = 91/353 (25%), Positives = 154/353 (43%), Gaps = 22/353 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG G G V + N+ GE +A+K Q R + E ++++++ H N+V
Sbjct: 15 WEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVV 74
Query: 72 KLLAIEEEQEGRGK----VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
+ E + ++ ME C GG L L+ EN GL+E L +L + + ++
Sbjct: 75 AARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALR 134
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
+L +N ++HRDLKP NI+ E +K+ D G A+EL + S GT +YL P++
Sbjct: 135 YLHENRIIHRDLKPENIVLQQGEQ-RLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPEL 193
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGV 247
E+ + + TVD WS G + TG PF P + ++ ++ S V
Sbjct: 194 LEQ--------QKYTVTVDYWSFGTLAFECITGFRPFLP----NWQPVQWHSKVRQKSEV 241
Query: 248 ISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERF-----FS 302
NG + ++ LP L+ L + + L +L P + T + F
Sbjct: 242 DIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFK 301
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILL 355
+ + + K VH+ + T + +E L + + T + E Q LL
Sbjct: 302 ALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELL 354
>AF029684-1|AAC51860.1| 756|Homo sapiens IkB kinase-beta protein.
Length = 756
Score = 120 bits (290), Expect = 1e-26
Identities = 91/353 (25%), Positives = 154/353 (43%), Gaps = 22/353 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG G G V + N+ GE +A+K Q R + E ++++++ H N+V
Sbjct: 15 WEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVV 74
Query: 72 KLLAIEEEQEGRGK----VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
+ E + ++ ME C GG L L+ EN GL+E L +L + + ++
Sbjct: 75 AARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALR 134
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
+L +N ++HRDLKP NI+ E +K+ D G A+EL + S GT +YL P++
Sbjct: 135 YLHENRIIHRDLKPENIVLQQGEQ-RLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPEL 193
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGV 247
E+ + + TVD WS G + TG PF P + ++ ++ S V
Sbjct: 194 LEQ--------QKYTVTVDYWSFGTLAFECITGFRPFLP----NWQPVQWHSKVRQKSEV 241
Query: 248 ISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERF-----FS 302
NG + ++ LP L+ L + + L +L P + T + F
Sbjct: 242 DIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFK 301
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILL 355
+ + + K VH+ + T + +E L + + T + E Q LL
Sbjct: 302 ALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELL 354
>AB209028-1|BAD92265.1| 726|Homo sapiens conserved helix-loop-helix
ubiquitous kinase variant protein.
Length = 726
Score = 120 bits (290), Expect = 1e-26
Identities = 95/362 (26%), Positives = 161/362 (44%), Gaps = 23/362 (6%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
LR W LG G G V ++ +A+K+ + + E +++K
Sbjct: 14 LRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMK 73
Query: 64 KVKHENIVKLLAIEEEQE---GRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
K+ H N+VK + EE ++ ME C+GG L +L+ PEN GL+E + L +L
Sbjct: 74 KLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLS 133
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +G+++L +N ++HRDLKP NI+ + G +K+ D G A+++ + S GT
Sbjct: 134 DIGSGIRYLHENKIIHRDLKPENIVLQ-DVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTL 192
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
+YL P+++E K + ATVD WS G ++ G +RP+ T
Sbjct: 193 QYLAPELFE--------NKPYTATVDYWSFGTMVFECIAG---YRPFLHHLQPFTWHEKI 241
Query: 241 TKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHR------- 293
KK I + +G + ++ LP L + + + L +L DP +
Sbjct: 242 KKKDPKCIFACEEM-SGEVRFSSHLPQPNSLCSLVVEPMENWLQLMLNWDPQQRGGPVDL 300
Query: 294 IWTFERFFSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQI 353
R F + + + K VH+ + A I L +E L + + +T + SQ
Sbjct: 301 TLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQE 360
Query: 354 LL 355
LL
Sbjct: 361 LL 362
>AF031416-1|AAC64675.1| 756|Homo sapiens IkB kinase beta subunit
protein.
Length = 756
Score = 119 bits (287), Expect = 2e-26
Identities = 91/353 (25%), Positives = 153/353 (43%), Gaps = 22/353 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG G G V + N+ GE +A+K Q R + E ++++++ H N+V
Sbjct: 15 WEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVV 74
Query: 72 KLLAIEEEQEGRGK----VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
+ E ++ ME C GG L L+ EN GL+E L +L + + ++
Sbjct: 75 AARDVPEGMXNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALR 134
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
+L +N ++HRDLKP NI+ E +K+ D G A+EL + S GT +YL P++
Sbjct: 135 YLHENRIIHRDLKPENIVLQQGEQ-RLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPEL 193
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKASGV 247
E+ + + TVD WS G + TG PF P + ++ ++ S V
Sbjct: 194 LEQ--------QKYTVTVDYWSFGTLAFECITGFRPFLP----NWQPVQWHSKVRQKSEV 241
Query: 248 ISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFERF-----FS 302
NG + ++ LP L+ L + + L +L P + T + F
Sbjct: 242 DIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFK 301
Query: 303 EVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQILL 355
+ + + K VH+ + T + +E L + + T + E Q LL
Sbjct: 302 ALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELL 354
>BC092514-1|AAH92514.1| 745|Homo sapiens conserved helix-loop-helix
ubiquitous kinase protein.
Length = 745
Score = 117 bits (281), Expect = 1e-25
Identities = 94/362 (25%), Positives = 160/362 (44%), Gaps = 23/362 (6%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLK 63
LR W LG G G V ++ +A+K+ + + E +++K
Sbjct: 7 LRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMK 66
Query: 64 KVKHENIVKLLAIEEEQE---GRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
K+ H N+VK + EE ++ ME C+GG L +L+ PEN GL+E + L +L
Sbjct: 67 KLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLS 126
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +G+++L +N ++HRDLKP NI+ + G +K+ D G A+++ + S GT
Sbjct: 127 DIGSGIRYLHENKIIHRDLKPENIVLQ-DVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTL 185
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
+YL P+++E K + ATVD WS G ++ G +R + T
Sbjct: 186 QYLAPELFE--------NKPYTATVDYWSFGTMVFECIAG---YRLFLHHLQPFTWHEKI 234
Query: 241 TKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHR------- 293
KK I + +G + ++ LP L + + + L +L DP +
Sbjct: 235 KKKDPKCIFACEEM-SGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRGGPVDL 293
Query: 294 IWTFERFFSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQI 353
R F + + + K VH+ + A I L +E L + + +T + SQ
Sbjct: 294 TLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQE 353
Query: 354 LL 355
LL
Sbjct: 354 LL 355
>BC006231-1|AAH06231.1| 256|Homo sapiens IKBKB protein protein.
Length = 256
Score = 116 bits (280), Expect = 2e-25
Identities = 67/219 (30%), Positives = 106/219 (48%), Gaps = 13/219 (5%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG G G V + N+ GE +A+K Q R + E ++++++ H N+V
Sbjct: 15 WEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVV 74
Query: 72 KLLAIEEEQEGRGK----VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
+ E + ++ ME C GG L L+ EN GL+E L +L + + ++
Sbjct: 75 AARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALR 134
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDM 187
+L +N ++HRDLKP NI+ E +K+ D G A+EL + S GT +YL P++
Sbjct: 135 YLHENRIIHRDLKPENIVLQQGEQ-RLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPEL 193
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRP 226
E+ + + TVD WS G + TG PF P
Sbjct: 194 LEQ--------QKYTVTVDYWSFGTLAFECITGFRPFLP 224
>U22512-1|AAC50713.1| 714|Homo sapiens CHUK protein.
Length = 714
Score = 115 bits (277), Expect = 4e-25
Identities = 87/328 (26%), Positives = 151/328 (46%), Gaps = 23/328 (7%)
Query: 38 VAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIEEEQE---GRGKVIVMELCTG 94
+A+K+ + + E +++KK+ H N+VK + EE ++ ME C+G
Sbjct: 10 IAIKSCRLELSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSG 69
Query: 95 GSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTT 154
G L +L+ PEN GL+E + L +L + +G+++L +N ++HRDLKP NI+ + G
Sbjct: 70 GDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQ-DVGGKI 128
Query: 155 TYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTL 214
+K+ D G A+++ + S GT +YL P+++E K + ATVD WS G +
Sbjct: 129 IHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFE--------NKPYTATVDYWSFGTMV 180
Query: 215 YHVATGQLPFRPYGGRRNKETMFYITTKKASGVISGTQTTENGPIDWARELPPHCQLSVG 274
+ G +RP+ T KK I + +G + ++ LP L
Sbjct: 181 FECIAG---YRPFLHHLQPFTWHEKIKKKDPKCIFACEEM-SGEVRFSSHLPQPNSLCSL 236
Query: 275 LRKLVTPLLAGLLEVDPHR-------IWTFERFFSEVQVVTSTKPVHVFYVNKATSIKVF 327
+ + + L +L DP + R F + + + K VH+ + A I
Sbjct: 237 IVEPMENWLQLMLNWDPQQRGGPVDLTLKQPRCFVLMDHILNLKIVHILNMTSAKIISFL 296
Query: 328 LKLEEKYGHLHTYVCEQTSVVAESQILL 355
L +E L + + +T + SQ LL
Sbjct: 297 LPPDESLHSLQSRIERETGINTGSQELL 324
>BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein.
Length = 1036
Score = 103 bits (248), Expect = 1e-21
Identities = 68/223 (30%), Positives = 114/223 (51%), Gaps = 19/223 (8%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGE-PVAVKTFNQLSHMRPHDVQMREFEVLKKVKH 67
++ +S ++G GA VF+G ++ + VA+K+ N+ + + + +E ++LK+++H
Sbjct: 6 DFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQH 65
Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
ENIV L ++E +VME C GG L + L + T L E + L + A M+
Sbjct: 66 ENIVALYDVQELP--NSVFLVMEYCNGGDLADYL-QAKGT--LSEDTIRVFLHQIAAAMR 120
Query: 128 HLRDNNLVHRDLKPGNI-MKYINEDGTTT----YKLTDFGAARELQEEEQFVSLYGTEEY 182
L ++HRDLKP NI + Y N ++ K+ DFG AR L +L G+ Y
Sbjct: 121 ILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMY 180
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+ P++ + + + A DLWSIG +Y G+ PF+
Sbjct: 181 MAPEVI--------MSQHYDAKADLWSIGTVIYQCLVGKPPFQ 215
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 103 bits (248), Expect = 1e-21
Identities = 70/223 (31%), Positives = 109/223 (48%), Gaps = 21/223 (9%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGE-PVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
+ +S ++G GA VF+G ++ + VAVK N+ + + + +E ++LK++KHE
Sbjct: 14 FEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHE 73
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
NIV L +E +VME C GG L + L L E L L+ + M+
Sbjct: 74 NIVALYDFQE--MANSVYLVMEYCNGGDLADYLHAMRT---LSEDTIRLFLQQIAGAMRL 128
Query: 129 LRDNNLVHRDLKPGNIMKYINEDG------TTTYKLTDFGAARELQEEEQFVSLYGTEEY 182
L ++HRDLKP NI+ N G + K+ DFG AR LQ +L G+ Y
Sbjct: 129 LHSKGIIHRDLKPQNIL-LSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMY 187
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+ P++ + + + DLWSIG +Y TG+ PF+
Sbjct: 188 MAPEVI--------MSQHYDGKADLWSIGTIVYQCLTGKAPFQ 222
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 103 bits (248), Expect = 1e-21
Identities = 70/223 (31%), Positives = 109/223 (48%), Gaps = 21/223 (9%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGE-PVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
+ +S ++G GA VF+G ++ + VAVK N+ + + + +E ++LK++KHE
Sbjct: 30 FEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHE 89
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
NIV L +E +VME C GG L + L L E L L+ + M+
Sbjct: 90 NIVALYDFQE--MANSVYLVMEYCNGGDLADYLHAMRT---LSEDTIRLFLQQIAGAMRL 144
Query: 129 LRDNNLVHRDLKPGNIMKYINEDG------TTTYKLTDFGAARELQEEEQFVSLYGTEEY 182
L ++HRDLKP NI+ N G + K+ DFG AR LQ +L G+ Y
Sbjct: 145 LHSKGIIHRDLKPQNIL-LSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMY 203
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+ P++ + + + DLWSIG +Y TG+ PF+
Sbjct: 204 MAPEVI--------MSQHYDGKADLWSIGTIVYQCLTGKAPFQ 238
>AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein.
Length = 1100
Score = 103 bits (248), Expect = 1e-21
Identities = 68/223 (30%), Positives = 114/223 (51%), Gaps = 19/223 (8%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGE-PVAVKTFNQLSHMRPHDVQMREFEVLKKVKH 67
++ +S ++G GA VF+G ++ + VA+K+ N+ + + + +E ++LK+++H
Sbjct: 70 DFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQH 129
Query: 68 ENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
ENIV L ++E +VME C GG L + L + T L E + L + A M+
Sbjct: 130 ENIVALYDVQELP--NSVFLVMEYCNGGDLADYL-QAKGT--LSEDTIRVFLHQIAAAMR 184
Query: 128 HLRDNNLVHRDLKPGNI-MKYINEDGTTT----YKLTDFGAARELQEEEQFVSLYGTEEY 182
L ++HRDLKP NI + Y N ++ K+ DFG AR L +L G+ Y
Sbjct: 185 ILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMY 244
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+ P++ + + + A DLWSIG +Y G+ PF+
Sbjct: 245 MAPEVI--------MSQHYDAKADLWSIGTVIYQCLVGKPPFQ 279
>X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase
protein.
Length = 458
Score = 102 bits (245), Expect = 3e-21
Identities = 69/224 (30%), Positives = 118/224 (52%), Gaps = 18/224 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG G G VF+ V K + A K F S +++ +E ++ + H +V+ ++
Sbjct: 15 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIR-QEISIMNCLHHPKLVQ--CVD 71
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+E V+V+E+ +GG LF + D + + L E E + + ++ G++++ +VH
Sbjct: 72 AFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYIHKQGIVHL 129
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NIM +N+ G T KL DFG AR L+ L+GT E++ P++ + +P+
Sbjct: 130 DLKPENIM-CVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEV----INYEPI 183
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
G + D+WSIGV Y + +G PF G + ET+ +T+
Sbjct: 184 GYA----TDMWSIGVICYILVSGLSPFM---GDNDNETLANVTS 220
>U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase
protein.
Length = 1914
Score = 102 bits (245), Expect = 3e-21
Identities = 69/224 (30%), Positives = 118/224 (52%), Gaps = 18/224 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG G G VF+ V K + A K F S +++ +E ++ + H +V+ ++
Sbjct: 1470 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIR-QEISIMNCLHHPKLVQ--CVD 1526
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+E V+V+E+ +GG LF + D + + L E E + + ++ G++++ +VH
Sbjct: 1527 AFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYIHKQGIVHL 1584
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NIM +N+ G T KL DFG AR L+ L+GT E++ P++ + +P+
Sbjct: 1585 DLKPENIM-CVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEV----INYEPI 1638
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
G + D+WSIGV Y + +G PF G + ET+ +T+
Sbjct: 1639 GYA----TDMWSIGVICYILVSGLSPFM---GDNDNETLANVTS 1675
>AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain
kinase protein.
Length = 1914
Score = 102 bits (245), Expect = 3e-21
Identities = 69/224 (30%), Positives = 118/224 (52%), Gaps = 18/224 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG G G VF+ V K + A K F S +++ +E ++ + H +V+ ++
Sbjct: 1470 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIR-QEISIMNCLHHPKLVQ--CVD 1526
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+E V+V+E+ +GG LF + D + + L E E + + ++ G++++ +VH
Sbjct: 1527 AFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYIHKQGIVHL 1584
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NIM +N+ G T KL DFG AR L+ L+GT E++ P++ + +P+
Sbjct: 1585 DLKPENIM-CVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEV----INYEPI 1638
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
G + D+WSIGV Y + +G PF G + ET+ +T+
Sbjct: 1639 GYA----TDMWSIGVICYILVSGLSPFM---GDNDNETLANVTS 1675
>AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kinase
isoform 2 protein.
Length = 1845
Score = 102 bits (245), Expect = 3e-21
Identities = 69/224 (30%), Positives = 118/224 (52%), Gaps = 18/224 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG G G VF+ V K + A K F S +++ +E ++ + H +V+ ++
Sbjct: 1401 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIR-QEISIMNCLHHPKLVQ--CVD 1457
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+E V+V+E+ +GG LF + D + + L E E + + ++ G++++ +VH
Sbjct: 1458 AFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYIHKQGIVHL 1515
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NIM +N+ G T KL DFG AR L+ L+GT E++ P++ + +P+
Sbjct: 1516 DLKPENIM-CVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEV----INYEPI 1569
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
G + D+WSIGV Y + +G PF G + ET+ +T+
Sbjct: 1570 GYA----TDMWSIGVICYILVSGLSPFM---GDNDNETLANVTS 1606
>AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kinase
protein.
Length = 992
Score = 102 bits (245), Expect = 3e-21
Identities = 69/224 (30%), Positives = 118/224 (52%), Gaps = 18/224 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG G G VF+ V K + A K F S +++ +E ++ + H +V+ ++
Sbjct: 548 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIR-QEISIMNCLHHPKLVQ--CVD 604
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+E V+V+E+ +GG LF + D + + L E E + + ++ G++++ +VH
Sbjct: 605 AFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYIHKQGIVHL 662
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NIM +N+ G T KL DFG AR L+ L+GT E++ P++ + +P+
Sbjct: 663 DLKPENIM-CVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEV----INYEPI 716
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
G + D+WSIGV Y + +G PF G + ET+ +T+
Sbjct: 717 GYA----TDMWSIGVICYILVSGLSPFM---GDNDNETLANVTS 753
>BC032787-1|AAH32787.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 100 bits (240), Expect = 1e-20
Identities = 70/208 (33%), Positives = 111/208 (53%), Gaps = 16/208 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLG GA VF + G+ A+K + R ++ E VLKK+KHENIV L I
Sbjct: 28 VLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLE-NEIAVLKKIKHENIVTLEDI 86
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E +VM+L +GG LF+ + + Y E + LV++ + + +K+L +N +VH
Sbjct: 87 YESTTHY--YLVMQLVSGGELFDRILE-RGVY--TEKDASLVIQQVLSAVKYLHENGIVH 141
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP N++ Y+ + + +TDFG ++ +++ + GT Y+ P++ + +KP
Sbjct: 142 RDLKPENLL-YLTPEENSKIMITDFGLSK-MEQNGIMSTACGTPGYVAPEV----LAQKP 195
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
K+ VD WSIGV Y + G PF
Sbjct: 196 YSKA----VDCWSIGVITYILLCGYPPF 219
>AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain
polypeptide kinase isoform 1 protein.
Length = 1914
Score = 100 bits (240), Expect = 1e-20
Identities = 68/224 (30%), Positives = 118/224 (52%), Gaps = 18/224 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG G G VF+ V K + A K F S +++ +E ++ + +V+ ++
Sbjct: 1470 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIR-QEISIMNCLHPPKLVQ--CVD 1526
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+E V+V+E+ +GG LF + D + + L E E + + ++ G++++ +VH
Sbjct: 1527 AFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYIHKQGIVHL 1584
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NIM +N+ G T KL DFG AR L+ L+GT E++ P++ ++ +P+
Sbjct: 1585 DLKPENIM-CVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEV----IIYEPI 1638
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
G + D+WSIGV Y + +G PF G + ET+ +T+
Sbjct: 1639 GYA----TDMWSIGVICYILVSGLSPFM---GDNDNETLANVTS 1675
>AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain
polypeptide kinase isoform 2 protein.
Length = 1845
Score = 100 bits (240), Expect = 1e-20
Identities = 68/224 (30%), Positives = 118/224 (52%), Gaps = 18/224 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG G G VF+ V K + A K F S +++ +E ++ + +V+ ++
Sbjct: 1401 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIR-QEISIMNCLHPPKLVQ--CVD 1457
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+E V+V+E+ +GG LF + D + + L E E + + ++ G++++ +VH
Sbjct: 1458 AFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYIHKQGIVHL 1515
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NIM +N+ G T KL DFG AR L+ L+GT E++ P++ ++ +P+
Sbjct: 1516 DLKPENIM-CVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEV----IIYEPI 1569
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
G + D+WSIGV Y + +G PF G + ET+ +T+
Sbjct: 1570 GYA----TDMWSIGVICYILVSGLSPFM---GDNDNETLANVTS 1606
>AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein.
Length = 460
Score = 100 bits (240), Expect = 1e-20
Identities = 70/208 (33%), Positives = 111/208 (53%), Gaps = 16/208 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLG GA VF + G+ A+K + R ++ E VLKK+KHENIV L I
Sbjct: 28 VLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLE-NEIAVLKKIKHENIVTLEDI 86
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E +VM+L +GG LF+ + + Y E + LV++ + + +K+L +N +VH
Sbjct: 87 YESTTHY--YLVMQLVSGGELFDRILE-RGVY--TEKDASLVIQQVLSAVKYLHENGIVH 141
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP N++ Y+ + + +TDFG ++ +++ + GT Y+ P++ + +KP
Sbjct: 142 RDLKPENLL-YLTPEENSKIMITDFGLSK-MEQNGIMSTACGTPGYVAPEV----LAQKP 195
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
K+ VD WSIGV Y + G PF
Sbjct: 196 YSKA----VDCWSIGVITYILLCGYPPF 219
>AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein
protein.
Length = 481
Score = 100 bits (240), Expect = 1e-20
Identities = 70/208 (33%), Positives = 111/208 (53%), Gaps = 16/208 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLG GA VF + G+ A+K + R ++ E VLKK+KHENIV L I
Sbjct: 33 VLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLE-NEIAVLKKIKHENIVTLEDI 91
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E +VM+L +GG LF+ + + Y E + LV++ + + +K+L +N +VH
Sbjct: 92 YESTTHY--YLVMQLVSGGELFDRILE-RGVY--TEKDASLVIQQVLSAVKYLHENGIVH 146
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP N++ Y+ + + +TDFG ++ +++ + GT Y+ P++ + +KP
Sbjct: 147 RDLKPENLL-YLTPEENSKIMITDFGLSK-MEQNGIMSTACGTPGYVAPEV----LAQKP 200
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
K+ VD WSIGV Y + G PF
Sbjct: 201 YSKA----VDCWSIGVITYILLCGYPPF 224
>AL023754-3|CAI19991.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 100 bits (240), Expect = 1e-20
Identities = 70/208 (33%), Positives = 111/208 (53%), Gaps = 16/208 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLG GA VF + G+ A+K + R ++ E VLKK+KHENIV L I
Sbjct: 28 VLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLE-NEIAVLKKIKHENIVTLEDI 86
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E +VM+L +GG LF+ + + Y E + LV++ + + +K+L +N +VH
Sbjct: 87 YESTTHY--YLVMQLVSGGELFDRILE-RGVY--TEKDASLVIQQVLSAVKYLHENGIVH 141
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP N++ Y+ + + +TDFG ++ +++ + GT Y+ P++ + +KP
Sbjct: 142 RDLKPENLL-YLTPEENSKIMITDFGLSK-MEQNGIMSTACGTPGYVAPEV----LAQKP 195
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
K+ VD WSIGV Y + G PF
Sbjct: 196 YSKA----VDCWSIGVITYILLCGYPPF 219
>AF428261-1|AAL28100.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase I gamma
protein.
Length = 476
Score = 100 bits (240), Expect = 1e-20
Identities = 70/208 (33%), Positives = 111/208 (53%), Gaps = 16/208 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLG GA VF + G+ A+K + R ++ E VLKK+KHENIV L I
Sbjct: 28 VLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLE-NEIAVLKKIKHENIVTLEDI 86
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E +VM+L +GG LF+ + + Y E + LV++ + + +K+L +N +VH
Sbjct: 87 YESTTHY--YLVMQLVSGGELFDRILE-RGVY--TEKDASLVIQQVLSAVKYLHENGIVH 141
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RDLKP N++ Y+ + + +TDFG ++ +++ + GT Y+ P++ + +KP
Sbjct: 142 RDLKPENLL-YLTPEENSKIMITDFGLSK-MEQNGIMSTACGTPGYVAPEV----LAQKP 195
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
K+ VD WSIGV Y + G PF
Sbjct: 196 YSKA----VDCWSIGVITYILLCGYPPF 219
>BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein.
Length = 795
Score = 100 bits (239), Expect = 1e-20
Identities = 71/233 (30%), Positives = 112/233 (48%), Gaps = 18/233 (7%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK 66
S Y VLG G G V + K+ G P+A K S DV+ E ++ ++
Sbjct: 486 SAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVK-NEINIMNQLS 544
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
H N+++L E + +VME GG LF+ + D + Y L E + +L + G+
Sbjct: 545 HVNLIQLYDAFESKHSC--TLVMEYVDGGELFDRITDEK--YHLTELDVVLFTRQICEGV 600
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPD 186
+L + ++H DLKP NI+ +N+ G K+ DFG AR + E+ +GT E+L P+
Sbjct: 601 HYLHQHYILHLDLKPENIL-CVNQTG-HQIKIIDFGLARRYKPREKLKVNFGTPEFLAPE 658
Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
+ + P D+WS+GV Y + +G PF G + ETM +I
Sbjct: 659 VVNYEFVSFP--------TDMWSVGVITYMLLSGLSPFL---GETDAETMNFI 700
>AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kinase
(MLCK) protein.
Length = 795
Score = 100 bits (239), Expect = 1e-20
Identities = 71/233 (30%), Positives = 112/233 (48%), Gaps = 18/233 (7%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK 66
S Y VLG G G V + K+ G P+A K S DV+ E ++ ++
Sbjct: 486 SAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVK-NEINIMNQLS 544
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
H N+++L E + +VME GG LF+ + D + Y L E + +L + G+
Sbjct: 545 HVNLIQLYDAFESKHSC--TLVMEYVDGGELFDRITDEK--YHLTELDVVLFTRQICEGV 600
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPD 186
+L + ++H DLKP NI+ +N+ G K+ DFG AR + E+ +GT E+L P+
Sbjct: 601 HYLHQHYILHLDLKPENIL-CVNQTG-HQIKIIDFGLARRYKPREKLKVNFGTPEFLAPE 658
Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
+ + P D+WS+GV Y + +G PF G + ETM +I
Sbjct: 659 VVNYEFVSFP--------TDMWSVGVITYMLLSGLSPFL---GETDAETMNFI 700
>AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinase
transcript variant 4 protein.
Length = 510
Score = 99.1 bits (236), Expect = 3e-20
Identities = 79/245 (32%), Positives = 120/245 (48%), Gaps = 27/245 (11%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVK-----TFNQLSHMRPHDVQMRE 58
L+ E +W+ +LGKGA G V+ G+ + G+ +AVK T N+L+ + + E
Sbjct: 235 LKSEEPILWTKGEILGKGAYGTVYCGLT-SQGQLIAVKQVALDTSNKLAAEKEYRKLQEE 293
Query: 59 FEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLL 117
++LK +KH NIV L ++ I ME GGS+ +I+ N +G L E F
Sbjct: 294 VDLLKALKHVNIVAYLGTCLQENTVS--IFMEFVPGGSISSII----NRFGPLPEMVFCK 347
Query: 118 VLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY 177
+ + G+ +L +N +VHRD+K N+M T KL DFG AR L + L
Sbjct: 348 YTKQILQGVAYLHENCVVHRDIKGNNVMLM----PTGIIKLIDFGCARRL----AWAGLN 399
Query: 178 GTEEYLHPDMYERAVLRKP--VGKS-FGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKE 234
GT + M+ P + +S +G D+WSIG T++ +ATG+ P
Sbjct: 400 GTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGK---PPLASMDRMA 456
Query: 235 TMFYI 239
MFYI
Sbjct: 457 AMFYI 461
>AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinase
transcript variant 2 protein.
Length = 1215
Score = 99.1 bits (236), Expect = 3e-20
Identities = 79/245 (32%), Positives = 120/245 (48%), Gaps = 27/245 (11%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVK-----TFNQLSHMRPHDVQMRE 58
L+ E +W+ +LGKGA G V+ G+ + G+ +AVK T N+L+ + + E
Sbjct: 940 LKSEEPILWTKGEILGKGAYGTVYCGLT-SQGQLIAVKQVALDTSNKLAAEKEYRKLQEE 998
Query: 59 FEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLL 117
++LK +KH NIV L ++ I ME GGS+ +I+ N +G L E F
Sbjct: 999 VDLLKALKHVNIVAYLGTCLQENTVS--IFMEFVPGGSISSII----NRFGPLPEMVFCK 1052
Query: 118 VLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY 177
+ + G+ +L +N +VHRD+K N+M T KL DFG AR L + L
Sbjct: 1053 YTKQILQGVAYLHENCVVHRDIKGNNVMLM----PTGIIKLIDFGCARRL----AWAGLN 1104
Query: 178 GTEEYLHPDMYERAVLRKP--VGKS-FGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKE 234
GT + M+ P + +S +G D+WSIG T++ +ATG+ P
Sbjct: 1105 GTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGK---PPLASMDRMA 1161
Query: 235 TMFYI 239
MFYI
Sbjct: 1162 AMFYI 1166
>AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinase
transcript variant 1 protein.
Length = 1328
Score = 99.1 bits (236), Expect = 3e-20
Identities = 79/245 (32%), Positives = 120/245 (48%), Gaps = 27/245 (11%)
Query: 4 LRGSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVK-----TFNQLSHMRPHDVQMRE 58
L+ E +W+ +LGKGA G V+ G+ + G+ +AVK T N+L+ + + E
Sbjct: 1053 LKSEEPILWTKGEILGKGAYGTVYCGLT-SQGQLIAVKQVALDTSNKLAAEKEYRKLQEE 1111
Query: 59 FEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLL 117
++LK +KH NIV L ++ I ME GGS+ +I+ N +G L E F
Sbjct: 1112 VDLLKALKHVNIVAYLGTCLQENTVS--IFMEFVPGGSISSII----NRFGPLPEMVFCK 1165
Query: 118 VLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY 177
+ + G+ +L +N +VHRD+K N+M T KL DFG AR L + L
Sbjct: 1166 YTKQILQGVAYLHENCVVHRDIKGNNVMLM----PTGIIKLIDFGCARRL----AWAGLN 1217
Query: 178 GTEEYLHPDMYERAVLRKP--VGKS-FGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKE 234
GT + M+ P + +S +G D+WSIG T++ +ATG+ P
Sbjct: 1218 GTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGK---PPLASMDRMA 1274
Query: 235 TMFYI 239
MFYI
Sbjct: 1275 AMFYI 1279
>X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein.
Length = 912
Score = 98.3 bits (234), Expect = 6e-20
Identities = 68/209 (32%), Positives = 104/209 (49%), Gaps = 14/209 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLA 75
VLG G G V+ G ++ G VA+K ++L + Q+R E +L+ + H +V L
Sbjct: 588 VLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNLHHPGVVNLEC 647
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E E +VME G L IL + L E+ ++ + ++HL N+V
Sbjct: 648 MFETPER--VFVVMEKLHGDMLEMILSSEKGR--LPEHITKFLITQILVALRHLHFKNIV 703
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
H DLKP N++ + D KL DFG AR + E+ S+ GT YL P+ VLR
Sbjct: 704 HCDLKPENVL-LASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPE-----VLR- 756
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + ++D+WS+GV +Y +G PF
Sbjct: 757 --NKGYNRSLDMWSVGVIIYVSLSGTFPF 783
>DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein.
Length = 914
Score = 98.3 bits (234), Expect = 6e-20
Identities = 68/209 (32%), Positives = 104/209 (49%), Gaps = 14/209 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLA 75
VLG G G V+ G ++ G VA+K ++L + Q+R E +L+ + H +V L
Sbjct: 590 VLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNLHHPGVVNLEC 649
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E E +VME G L IL + L E+ ++ + ++HL N+V
Sbjct: 650 MFETPER--VFVVMEKLHGDMLEMILSSEKGR--LPEHITKFLITQILVALRHLHFKNIV 705
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
H DLKP N++ + D KL DFG AR + E+ S+ GT YL P+ VLR
Sbjct: 706 HCDLKPENVL-LASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPE-----VLR- 758
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + ++D+WS+GV +Y +G PF
Sbjct: 759 --NKGYNRSLDMWSVGVIIYVSLSGTFPF 785
>BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein.
Length = 363
Score = 97.9 bits (233), Expect = 8e-20
Identities = 68/210 (32%), Positives = 106/210 (50%), Gaps = 16/210 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLA 75
VLG G G V+ G ++ G VAVK ++L + Q+R E +L+ ++H IV L
Sbjct: 41 VLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLEC 100
Query: 76 IEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E E KV +VME G L IL + + +FL+ + ++HL N+
Sbjct: 101 MFETPE---KVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLIT--QILVALRHLHFKNI 155
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
VH DLKP N++ + D KL DFG AR + E+ S+ GT YL P++
Sbjct: 156 VHCDLKPENVL-LASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVL------ 208
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + + ++D+WS+GV +Y +G PF
Sbjct: 209 --LNQGYNRSLDMWSVGVIMYVSLSGTFPF 236
>AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ90785 fis, clone THYRO1001457, moderately
similar to H.sapiens mRNA for protein kinase C mu. ).
Length = 721
Score = 97.9 bits (233), Expect = 8e-20
Identities = 68/210 (32%), Positives = 106/210 (50%), Gaps = 16/210 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLA 75
VLG G G V+ G ++ G VAVK ++L + Q+R E +L+ ++H IV L
Sbjct: 399 VLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLEC 458
Query: 76 IEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E E KV +VME G L IL + + +FL+ + ++HL N+
Sbjct: 459 MFETPE---KVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLIT--QILVALRHLHFKNI 513
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
VH DLKP N++ + D KL DFG AR + E+ S+ GT YL P++
Sbjct: 514 VHCDLKPENVL-LASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVL------ 566
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + + ++D+WS+GV +Y +G PF
Sbjct: 567 --LNQGYNRSLDMWSVGVIMYVSLSGTFPF 594
>AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ90192 fis, clone MAMMA1001150, moderately
similar to PROTEIN KINASE C, MU TYPE (EC 2.7.1.-). ).
Length = 721
Score = 97.9 bits (233), Expect = 8e-20
Identities = 68/210 (32%), Positives = 106/210 (50%), Gaps = 16/210 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLA 75
VLG G G V+ G ++ G VAVK ++L + Q+R E +L+ ++H IV L
Sbjct: 399 VLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLEC 458
Query: 76 IEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E E KV +VME G L IL + + +FL+ + ++HL N+
Sbjct: 459 MFETPE---KVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLIT--QILVALRHLHFKNI 513
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
VH DLKP N++ + D KL DFG AR + E+ S+ GT YL P++
Sbjct: 514 VHCDLKPENVL-LASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVL------ 566
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + + ++D+WS+GV +Y +G PF
Sbjct: 567 --LNQGYNRSLDMWSVGVIMYVSLSGTFPF 594
>AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein.
Length = 878
Score = 97.9 bits (233), Expect = 8e-20
Identities = 68/210 (32%), Positives = 106/210 (50%), Gaps = 16/210 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLA 75
VLG G G V+ G ++ G VAVK ++L + Q+R E +L+ ++H IV L
Sbjct: 556 VLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLEC 615
Query: 76 IEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E E KV +VME G L IL + + +FL+ + ++HL N+
Sbjct: 616 MFETPE---KVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLIT--QILVALRHLHFKNI 670
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
VH DLKP N++ + D KL DFG AR + E+ S+ GT YL P++
Sbjct: 671 VHCDLKPENVL-LASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVL------ 723
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + + ++D+WS+GV +Y +G PF
Sbjct: 724 --LNQGYNRSLDMWSVGVIMYVSLSGTFPF 751
>BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein.
Length = 592
Score = 97.5 bits (232), Expect = 1e-19
Identities = 67/219 (30%), Positives = 116/219 (52%), Gaps = 22/219 (10%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENI 70
++ T +G+G+ G V + +KN G+ VA+K F + + + MRE + LK+ HEN+
Sbjct: 3 MYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENL 62
Query: 71 VKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPEN-TYGLQEYEFLLVLEHLTAGMKH 128
V L+ + +++ K+ +V E +LD+ ++ +GL+ L + + +
Sbjct: 63 VNLIEVFRQKK---KIHLVFEFID----HTVLDELQHYCHGLESKRLRKYLFQILRAIDY 115
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDM 187
L NN++HRD+KP NI+ +++ G T KL DFG AR L + Y T Y P++
Sbjct: 116 LHSNNIIHRDIKPENIL--VSQSGIT--KLCDFGFARTLAAPGDIYTDYVATRWYRAPEL 171
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRP 226
VL+ S+G VD+W++G + +ATG P+ P
Sbjct: 172 ----VLK---DTSYGKPVDIWALGCMIIEMATGN-PYLP 202
>AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 97.5 bits (232), Expect = 1e-19
Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 17/220 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V + V ++ A+K + + E +L++VKH NIV L IE
Sbjct: 396 IGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV--LLIE 453
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E +VMEL GG LF+ + N Y E + +L +L + +K+L N+VHR
Sbjct: 454 EMDVPTELYLVMELVKGGDLFDAITST-NKY--TERDASGMLYNLASAIKYLHSLNIVHR 510
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP N++ Y ++DG+ + KL DFG A + + ++ GT Y+ P++
Sbjct: 511 DIKPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET------ 562
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
+G VD+W+ GV Y + G PFR G ++E +F
Sbjct: 563 --GYGLKVDIWAAGVITYILLCGFPPFR--GSGDDQEVLF 598
>AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 97.5 bits (232), Expect = 1e-19
Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 17/220 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V + V ++ A+K + + E +L++VKH NIV L IE
Sbjct: 396 IGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV--LLIE 453
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E +VMEL GG LF+ + N Y E + +L +L + +K+L N+VHR
Sbjct: 454 EMDVPTELYLVMELVKGGDLFDAITST-NKY--TERDASGMLYNLASAIKYLHSLNIVHR 510
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP N++ Y ++DG+ + KL DFG A + + ++ GT Y+ P++
Sbjct: 511 DIKPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET------ 562
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
+G VD+W+ GV Y + G PFR G ++E +F
Sbjct: 563 --GYGLKVDIWAAGVITYILLCGFPPFR--GSGDDQEVLF 598
>AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 97.5 bits (232), Expect = 1e-19
Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 17/220 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V + V ++ A+K + + E +L++VKH NIV L IE
Sbjct: 396 IGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV--LLIE 453
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E +VMEL GG LF+ + N Y E + +L +L + +K+L N+VHR
Sbjct: 454 EMDVPTELYLVMELVKGGDLFDAITST-NKY--TERDASGMLYNLASAIKYLHSLNIVHR 510
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP N++ Y ++DG+ + KL DFG A + + ++ GT Y+ P++
Sbjct: 511 DIKPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET------ 562
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
+G VD+W+ GV Y + G PFR G ++E +F
Sbjct: 563 --GYGLKVDIWAAGVITYILLCGFPPFR--GSGDDQEVLF 598
>AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 97.5 bits (232), Expect = 1e-19
Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 17/220 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V + V ++ A+K + + E +L++VKH NIV L IE
Sbjct: 396 IGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV--LLIE 453
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E +VMEL GG LF+ + N Y E + +L +L + +K+L N+VHR
Sbjct: 454 EMDVPTELYLVMELVKGGDLFDAITST-NKY--TERDASGMLYNLASAIKYLHSLNIVHR 510
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP N++ Y ++DG+ + KL DFG A + + ++ GT Y+ P++
Sbjct: 511 DIKPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET------ 562
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
+G VD+W+ GV Y + G PFR G ++E +F
Sbjct: 563 --GYGLKVDIWAAGVITYILLCGFPPFR--GSGDDQEVLF 598
>AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 433
Score = 97.5 bits (232), Expect = 1e-19
Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 17/220 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V + V ++ A+K + + E +L++VKH NIV L IE
Sbjct: 89 IGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV--LLIE 146
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E +VMEL GG LF+ + N Y E + +L +L + +K+L N+VHR
Sbjct: 147 EMDVPTELYLVMELVKGGDLFDAITST-NKY--TERDASGMLYNLASAIKYLHSLNIVHR 203
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP N++ Y ++DG+ + KL DFG A + + ++ GT Y+ P++
Sbjct: 204 DIKPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET------ 255
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
+G VD+W+ GV Y + G PFR G ++E +F
Sbjct: 256 --GYGLKVDIWAAGVITYILLCGFPPFR--GSGDDQEVLF 291
>AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 97.5 bits (232), Expect = 1e-19
Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 17/220 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V + V ++ A+K + + E +L++VKH NIV L IE
Sbjct: 396 IGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV--LLIE 453
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E +VMEL GG LF+ + N Y E + +L +L + +K+L N+VHR
Sbjct: 454 EMDVPTELYLVMELVKGGDLFDAITST-NKY--TERDASGMLYNLASAIKYLHSLNIVHR 510
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP N++ Y ++DG+ + KL DFG A + + ++ GT Y+ P++
Sbjct: 511 DIKPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET------ 562
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
+G VD+W+ GV Y + G PFR G ++E +F
Sbjct: 563 --GYGLKVDIWAAGVITYILLCGFPPFR--GSGDDQEVLF 598
>AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 97.5 bits (232), Expect = 1e-19
Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 17/220 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V + V ++ A+K + + E +L++VKH NIV L IE
Sbjct: 396 IGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV--LLIE 453
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E +VMEL GG LF+ + N Y E + +L +L + +K+L N+VHR
Sbjct: 454 EMDVPTELYLVMELVKGGDLFDAITST-NKY--TERDASGMLYNLASAIKYLHSLNIVHR 510
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP N++ Y ++DG+ + KL DFG A + + ++ GT Y+ P++
Sbjct: 511 DIKPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET------ 562
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
+G VD+W+ GV Y + G PFR G ++E +F
Sbjct: 563 --GYGLKVDIWAAGVITYILLCGFPPFR--GSGDDQEVLF 598
>AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 97.5 bits (232), Expect = 1e-19
Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 17/220 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V + V ++ A+K + + E +L++VKH NIV L IE
Sbjct: 396 IGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV--LLIE 453
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E +VMEL GG LF+ + N Y E + +L +L + +K+L N+VHR
Sbjct: 454 EMDVPTELYLVMELVKGGDLFDAITST-NKY--TERDASGMLYNLASAIKYLHSLNIVHR 510
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP N++ Y ++DG+ + KL DFG A + + ++ GT Y+ P++
Sbjct: 511 DIKPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET------ 562
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
+G VD+W+ GV Y + G PFR G ++E +F
Sbjct: 563 --GYGLKVDIWAAGVITYILLCGFPPFR--GSGDDQEVLF 598
>AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 97.5 bits (232), Expect = 1e-19
Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 17/220 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V + V ++ A+K + + E +L++VKH NIV L IE
Sbjct: 396 IGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV--LLIE 453
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E +VMEL GG LF+ + N Y E + +L +L + +K+L N+VHR
Sbjct: 454 EMDVPTELYLVMELVKGGDLFDAITST-NKY--TERDASGMLYNLASAIKYLHSLNIVHR 510
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP N++ Y ++DG+ + KL DFG A + + ++ GT Y+ P++
Sbjct: 511 DIKPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET------ 562
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
+G VD+W+ GV Y + G PFR G ++E +F
Sbjct: 563 --GYGLKVDIWAAGVITYILLCGFPPFR--GSGDDQEVLF 598
>AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protein
kinase NKIAMRE protein.
Length = 455
Score = 97.5 bits (232), Expect = 1e-19
Identities = 67/219 (30%), Positives = 116/219 (52%), Gaps = 22/219 (10%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENI 70
++ T +G+G+ G V + +KN G+ VA+K F + + + MRE + LK+ HEN+
Sbjct: 3 MYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENL 62
Query: 71 VKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPEN-TYGLQEYEFLLVLEHLTAGMKH 128
V L+ + +++ K+ +V E +LD+ ++ +GL+ L + + +
Sbjct: 63 VNLIEVFRQKK---KIHLVFEFID----HTVLDELQHYCHGLESKRLRKYLFQILRAIDY 115
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDM 187
L NN++HRD+KP NI+ +++ G T KL DFG AR L + Y T Y P++
Sbjct: 116 LHSNNIIHRDIKPENIL--VSQSGIT--KLCDFGFARTLAAPGDIYTDYVATRWYRAPEL 171
Query: 188 YERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRP 226
VL+ S+G VD+W++G + +ATG P+ P
Sbjct: 172 ----VLK---DTSYGKPVDIWALGCMIIEMATGN-PYLP 202
>AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein.
Length = 794
Score = 97.5 bits (232), Expect = 1e-19
Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 17/220 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G V + V ++ A+K + + E +L++VKH NIV L IE
Sbjct: 461 IGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV--LLIE 518
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
E +VMEL GG LF+ + N Y E + +L +L + +K+L N+VHR
Sbjct: 519 EMDVPTELYLVMELVKGGDLFDAITST-NKY--TERDASGMLYNLASAIKYLHSLNIVHR 575
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
D+KP N++ Y ++DG+ + KL DFG A + + ++ GT Y+ P++
Sbjct: 576 DIKPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET------ 627
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
+G VD+W+ GV Y + G PFR G ++E +F
Sbjct: 628 --GYGLKVDIWAAGVITYILLCGFPPFR--GSGDDQEVLF 663
>BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein
LOC340156 protein.
Length = 388
Score = 96.7 bits (230), Expect = 2e-19
Identities = 64/215 (29%), Positives = 104/215 (48%), Gaps = 15/215 (6%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHEN 69
Y S T +LG G G V + G +A K M+ + E V+ ++ H N
Sbjct: 104 YTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRG-MKDKEEVKNEISVMNQLDHAN 162
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
+++L E + V+VME GG LF+ + D +Y L E + +L ++ + G++H+
Sbjct: 163 LIQLYDAFESKNDI--VLVMEYVDGGELFDRIID--ESYNLTELDTILFMKQICEGIRHM 218
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189
++H DLKP NI+ +N D K+ DFG AR + E+ +GT E+L P++
Sbjct: 219 HQMYILHLDLKPENIL-CVNRD-AKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVN 276
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P D+WS+GV Y + +G PF
Sbjct: 277 YDFVSFP--------TDMWSVGVIAYMLLSGLSPF 303
>BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein
LOC340156 protein.
Length = 388
Score = 96.7 bits (230), Expect = 2e-19
Identities = 64/215 (29%), Positives = 104/215 (48%), Gaps = 15/215 (6%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHEN 69
Y S T +LG G G V + G +A K M+ + E V+ ++ H N
Sbjct: 104 YTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRG-MKDKEEVKNEISVMNQLDHAN 162
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
+++L E + V+VME GG LF+ + D +Y L E + +L ++ + G++H+
Sbjct: 163 LIQLYDAFESKNDI--VLVMEYVDGGELFDRIID--ESYNLTELDTILFMKQICEGIRHM 218
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189
++H DLKP NI+ +N D K+ DFG AR + E+ +GT E+L P++
Sbjct: 219 HQMYILHLDLKPENIL-CVNRD-AKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVN 276
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P D+WS+GV Y + +G PF
Sbjct: 277 YDFVSFP--------TDMWSVGVIAYMLLSGLSPF 303
>AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA
sequence from clone RP11-420G6 on chromosome 6. ).
Length = 388
Score = 96.7 bits (230), Expect = 2e-19
Identities = 64/215 (29%), Positives = 104/215 (48%), Gaps = 15/215 (6%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHEN 69
Y S T +LG G G V + G +A K M+ + E V+ ++ H N
Sbjct: 104 YTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRG-MKDKEEVKNEISVMNQLDHAN 162
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
+++L E + V+VME GG LF+ + D +Y L E + +L ++ + G++H+
Sbjct: 163 LIQLYDAFESKNDI--VLVMEYVDGGELFDRIID--ESYNLTELDTILFMKQICEGIRHM 218
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189
++H DLKP NI+ +N D K+ DFG AR + E+ +GT E+L P++
Sbjct: 219 HQMYILHLDLKPENIL-CVNRD-AKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVN 276
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P D+WS+GV Y + +G PF
Sbjct: 277 YDFVSFP--------TDMWSVGVIAYMLLSGLSPF 303
>AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA
sequence from clone RP11-145H9 on chromosome 6. ).
Length = 388
Score = 96.7 bits (230), Expect = 2e-19
Identities = 64/215 (29%), Positives = 104/215 (48%), Gaps = 15/215 (6%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHEN 69
Y S T +LG G G V + G +A K M+ + E V+ ++ H N
Sbjct: 104 YTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRG-MKDKEEVKNEISVMNQLDHAN 162
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
+++L E + V+VME GG LF+ + D +Y L E + +L ++ + G++H+
Sbjct: 163 LIQLYDAFESKNDI--VLVMEYVDGGELFDRIID--ESYNLTELDTILFMKQICEGIRHM 218
Query: 130 RDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYE 189
++H DLKP NI+ +N D K+ DFG AR + E+ +GT E+L P++
Sbjct: 219 HQMYILHLDLKPENIL-CVNRD-AKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVN 276
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P D+WS+GV Y + +G PF
Sbjct: 277 YDFVSFP--------TDMWSVGVIAYMLLSGLSPF 303
>AB209090-1|BAD92327.1| 483|Homo sapiens inhibitor of kappa light
polypeptide gene enhancer in B-cells, kinase beta vari
protein.
Length = 483
Score = 96.7 bits (230), Expect = 2e-19
Identities = 77/301 (25%), Positives = 131/301 (43%), Gaps = 22/301 (7%)
Query: 64 KVKHENIVKLLAIEEEQEGRGK----VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVL 119
++ H N+V + E + ++ ME C GG L L+ EN GL+E L +L
Sbjct: 18 RLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLL 77
Query: 120 EHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGT 179
+ + +++L +N ++HRDLKP NI+ E +K+ D G A+EL + S GT
Sbjct: 78 SDIASALRYLHENRIIHRDLKPENIVLQQGEQ-RLIHKIIDLGYAKELDQGSLCTSFVGT 136
Query: 180 EEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
+YL P++ E+ + + TVD WS G + TG PF P + ++
Sbjct: 137 LQYLAPELLEQ--------QKYTVTVDYWSFGTLAFECITGFRPFLP----NWQPVQWHS 184
Query: 240 TTKKASGVISGTQTTENGPIDWARELPPHCQLSVGLRKLVTPLLAGLLEVDPHRIWTFER 299
++ S V NG + ++ LP L+ L + + L +L P + T
Sbjct: 185 KVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPT 244
Query: 300 F-----FSEVQVVTSTKPVHVFYVNKATSIKVFLKLEEKYGHLHTYVCEQTSVVAESQIL 354
+ F + + + K VH+ + T + +E L + + T + E Q L
Sbjct: 245 YGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQEL 304
Query: 355 L 355
L
Sbjct: 305 L 305
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 96.7 bits (230), Expect = 2e-19
Identities = 65/228 (28%), Positives = 112/228 (49%), Gaps = 17/228 (7%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
+ T V+G G V + ++ + A+K ++ D+ E +++ + H NIV
Sbjct: 316 YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIV 375
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KL + E +++E GG LF+ + + + E + L++ L + H+ D
Sbjct: 376 KLHEVYETD--MEIYLILEYVQGGDLFDAIIE---SVKFPEPDAALMIMDLCKALVHMHD 430
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERA 191
++VHRDLKP N++ NED +TT KL DFG A+ + ++ GT Y+ P++
Sbjct: 431 KSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHV--VRPIFTVCGTPTYVAPEILSE- 487
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYI 239
K +G VD+W+ GV LY + G PFR R+++ +F I
Sbjct: 488 -------KGYGLEVDMWAAGVILYILLCGFPPFR--SPERDQDELFNI 526
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 95.9 bits (228), Expect = 3e-19
Identities = 69/213 (32%), Positives = 111/213 (52%), Gaps = 23/213 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQM---REFEVLKKVKHENIVKLL 74
LG+G+ V +G++ GE VA+K ++ + V RE ++ + ++H NI +LL
Sbjct: 68 LGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLL 127
Query: 75 AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNL 134
I E + +VMELC GG+L + + + + L+E E + L + ++HL +
Sbjct: 128 DILETENSY--YLVMELCPGGNLMHKIYEKKR---LEESEARRYIRQLISAVEHLHRAGV 182
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFG---AARELQEEEQFVSLYGTEEYLHPDMYERA 191
VHRDLK N++ ++ED KL DFG A L + F + G+ Y P++ R
Sbjct: 183 VHRDLKIENLL--LDEDNNI--KLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLAR- 237
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K +G +D+WSIGV +Y + TG LPF
Sbjct: 238 -------KKYGPKIDVWSIGVNMYAMLTGTLPF 263
>BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H1
protein.
Length = 424
Score = 95.5 bits (227), Expect = 4e-19
Identities = 64/211 (30%), Positives = 116/211 (54%), Gaps = 17/211 (8%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
+++G+G+ V + ++ +P A+K + + +V E VL++V+H NI++L+
Sbjct: 102 ALIGRGSFSRVVRVEHRATRQPYAIKMI-ETKYREGREVCESELRVLRRVRHANIIQLVE 160
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E QE +VMEL TGG LF+ + + E + VL+ + G+++L +
Sbjct: 161 VFETQER--VYMVMELATGGELFDRIIAKGS---FTERDATRVLQMVLDGVRYLHALGIT 215
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFG--AARELQEEEQFVSLYGTEEYLHPDMYERAVL 193
HRDLKP N++ Y + + +TDFG +AR+ ++ + GT EY+ P++ ++
Sbjct: 216 HRDLKPENLL-YYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEV----LV 270
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
RKP S VD+W++GV Y + +G +PF
Sbjct: 271 RKPYTNS----VDMWALGVIAYILLSGTMPF 297
>AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase
protein.
Length = 424
Score = 95.5 bits (227), Expect = 4e-19
Identities = 64/211 (30%), Positives = 116/211 (54%), Gaps = 17/211 (8%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
+++G+G+ V + ++ +P A+K + + +V E VL++V+H NI++L+
Sbjct: 102 ALIGRGSFSRVVRVEHRATRQPYAIKMI-ETKYREGREVCESELRVLRRVRHANIIQLVE 160
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E QE +VMEL TGG LF+ + + E + VL+ + G+++L +
Sbjct: 161 VFETQER--VYMVMELATGGELFDRIIAKGS---FTERDATRVLQMVLDGVRYLHALGIT 215
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFG--AARELQEEEQFVSLYGTEEYLHPDMYERAVL 193
HRDLKP N++ Y + + +TDFG +AR+ ++ + GT EY+ P++ ++
Sbjct: 216 HRDLKPENLL-YYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEV----LV 270
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
RKP S VD+W++GV Y + +G +PF
Sbjct: 271 RKPYTNS----VDMWALGVIAYILLSGTMPF 297
>U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-dependent
protein kinase II protein.
Length = 315
Score = 95.1 bits (226), Expect = 6e-19
Identities = 74/209 (35%), Positives = 101/209 (48%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V K + + A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + + + + H+ +++VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDIWACGVILYILLVGYPPF 214
>BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 95.1 bits (226), Expect = 6e-19
Identities = 71/228 (31%), Positives = 113/228 (49%), Gaps = 21/228 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQ--LSHMR---PHDVQMREFEVLKKVKHENIVK 72
LG G V + K G+ A K + LS R + RE +L++++H NI+
Sbjct: 19 LGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRHPNIIT 78
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
L I E + V+++EL +GG LF+ L + E+ L E E L+ + G+ +L
Sbjct: 79 LHDIFENKTD--VVLILELVSGGELFDFLAEKES---LTEDEATQFLKQILDGVHYLHSK 133
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAV 192
+ H DLKP NIM KL DFG A +++ +F +++GT E++ P++ V
Sbjct: 134 RIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEI----V 189
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
+P+ G D+WSIGV Y + +G PF G +ET+ I+
Sbjct: 190 NYEPL----GLEADMWSIGVITYILLSGASPFL---GETKQETLTNIS 230
>BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 95.1 bits (226), Expect = 6e-19
Identities = 71/228 (31%), Positives = 113/228 (49%), Gaps = 21/228 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQ--LSHMR---PHDVQMREFEVLKKVKHENIVK 72
LG G V + K G+ A K + LS R + RE +L++++H NI+
Sbjct: 19 LGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRHPNIIT 78
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
L I E + V+++EL +GG LF+ L + E+ L E E L+ + G+ +L
Sbjct: 79 LHDIFENKTD--VVLILELVSGGELFDFLAEKES---LTEDEATQFLKQILDGVHYLHSK 133
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAV 192
+ H DLKP NIM KL DFG A +++ +F +++GT E++ P++ V
Sbjct: 134 RIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEI----V 189
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
+P+ G D+WSIGV Y + +G PF G +ET+ I+
Sbjct: 190 NYEPL----GLEADMWSIGVITYILLSGASPFL---GETKQETLTNIS 230
>BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein.
Length = 625
Score = 95.1 bits (226), Expect = 6e-19
Identities = 62/218 (28%), Positives = 110/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ E+ +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AEYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein.
Length = 664
Score = 95.1 bits (226), Expect = 6e-19
Identities = 62/218 (28%), Positives = 110/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ E+ +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AEYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein.
Length = 247
Score = 95.1 bits (226), Expect = 6e-19
Identities = 62/218 (28%), Positives = 110/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ E+ +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AEYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 95.1 bits (226), Expect = 6e-19
Identities = 62/218 (28%), Positives = 110/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ E+ +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AEYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>AL713896-5|CAI13788.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 95.1 bits (226), Expect = 6e-19
Identities = 74/209 (35%), Positives = 101/209 (48%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V K + + A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + + + + H+ +++VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDIWACGVILYILLVGYPPF 214
>AL713896-4|CAI13789.1| 495|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 495
Score = 95.1 bits (226), Expect = 6e-19
Identities = 74/209 (35%), Positives = 101/209 (48%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V K + + A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + + + + H+ +++VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDIWACGVILYILLVGYPPF 214
>AL713896-3|CAI13790.1| 529|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 529
Score = 95.1 bits (226), Expect = 6e-19
Identities = 74/209 (35%), Positives = 101/209 (48%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V K + + A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + + + + H+ +++VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDIWACGVILYILLVGYPPF 214
>AL713896-2|CAI13791.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 95.1 bits (226), Expect = 6e-19
Identities = 74/209 (35%), Positives = 101/209 (48%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V K + + A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + + + + H+ +++VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDIWACGVILYILLVGYPPF 214
>AL596247-5|CAI13967.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 95.1 bits (226), Expect = 6e-19
Identities = 74/209 (35%), Positives = 101/209 (48%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V K + + A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + + + + H+ +++VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDIWACGVILYILLVGYPPF 214
>AL596247-4|CAI13966.1| 495|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 495
Score = 95.1 bits (226), Expect = 6e-19
Identities = 74/209 (35%), Positives = 101/209 (48%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V K + + A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + + + + H+ +++VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDIWACGVILYILLVGYPPF 214
>AL596247-3|CAI13965.1| 529|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 529
Score = 95.1 bits (226), Expect = 6e-19
Identities = 74/209 (35%), Positives = 101/209 (48%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V K + + A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + + + + H+ +++VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDIWACGVILYILLVGYPPF 214
>AL596247-2|CAI13968.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 95.1 bits (226), Expect = 6e-19
Identities = 74/209 (35%), Positives = 101/209 (48%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V K + + A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + + + + H+ +++VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDIWACGVILYILLVGYPPF 214
>AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 95.1 bits (226), Expect = 6e-19
Identities = 62/218 (28%), Positives = 110/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ E+ +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AEYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 95.1 bits (226), Expect = 6e-19
Identities = 62/218 (28%), Positives = 110/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ E+ +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AEYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein.
Length = 247
Score = 95.1 bits (226), Expect = 6e-19
Identities = 62/218 (28%), Positives = 110/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ E+ +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AEYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 95.1 bits (226), Expect = 6e-19
Identities = 62/218 (28%), Positives = 110/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ E+ +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AEYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 95.1 bits (226), Expect = 6e-19
Identities = 62/218 (28%), Positives = 110/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ E+ +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AEYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein.
Length = 1615
Score = 95.1 bits (226), Expect = 6e-19
Identities = 62/218 (28%), Positives = 110/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ E+ +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AEYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein.
Length = 454
Score = 95.1 bits (226), Expect = 6e-19
Identities = 71/228 (31%), Positives = 113/228 (49%), Gaps = 21/228 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQ--LSHMR---PHDVQMREFEVLKKVKHENIVK 72
LG G V + K G+ A K + LS R + RE +L++++H NI+
Sbjct: 19 LGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRHPNIIT 78
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
L I E + V+++EL +GG LF+ L + E+ L E E L+ + G+ +L
Sbjct: 79 LHDIFENKTD--VVLILELVSGGELFDFLAEKES---LTEDEATQFLKQILDGVHYLHSK 133
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAV 192
+ H DLKP NIM KL DFG A +++ +F +++GT E++ P++ V
Sbjct: 134 RIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEI----V 189
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
+P+ G D+WSIGV Y + +G PF G +ET+ I+
Sbjct: 190 NYEPL----GLEADMWSIGVITYILLSGASPFL---GETKQETLTNIS 230
>AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein.
Length = 454
Score = 95.1 bits (226), Expect = 6e-19
Identities = 71/228 (31%), Positives = 113/228 (49%), Gaps = 21/228 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQ--LSHMR---PHDVQMREFEVLKKVKHENIVK 72
LG G V + K G+ A K + LS R + RE +L++++H NI+
Sbjct: 19 LGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRHPNIIT 78
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
L I E + V+++EL +GG LF+ L + E+ L E E L+ + G+ +L
Sbjct: 79 LHDIFENKTD--VVLILELVSGGELFDFLAEKES---LTEDEATQFLKQILDGVHYLHSK 133
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAV 192
+ H DLKP NIM KL DFG A +++ +F +++GT E++ P++ V
Sbjct: 134 RIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEI----V 189
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYIT 240
+P+ G D+WSIGV Y + +G PF G +ET+ I+
Sbjct: 190 NYEPL----GLEADMWSIGVITYILLSGASPFL---GETKQETLTNIS 230
>AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related protein
1 protein.
Length = 370
Score = 94.3 bits (224), Expect = 1e-18
Identities = 60/185 (32%), Positives = 98/185 (52%), Gaps = 16/185 (8%)
Query: 57 REFEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFL 116
RE +L++V H N++ L + E + V+++EL +GG LF+ L E+ L E E
Sbjct: 73 REVSILRQVLHHNVITLHDVYENRTD--VVLILELVSGGELFDFLAQKES---LSEEEAT 127
Query: 117 LVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSL 176
++ + G+ +L + H DLKP NIM KL DFG A E+++ +F ++
Sbjct: 128 SFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNI 187
Query: 177 YGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETM 236
+GT E++ P++ V +P+ G D+WSIGV Y + +G PF G +ET+
Sbjct: 188 FGTPEFVAPEI----VNYEPL----GLEADMWSIGVITYILLSGASPFL---GDTKQETL 236
Query: 237 FYITT 241
IT+
Sbjct: 237 ANITS 241
>L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin dependent
protein kinase protein.
Length = 473
Score = 93.9 bits (223), Expect = 1e-18
Identities = 67/222 (30%), Positives = 110/222 (49%), Gaps = 20/222 (9%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
S LG+GAT V++ K +P A+K + + + E VL ++ H NI+KL
Sbjct: 50 SELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKK---IVRTEIGVLLRLSHPNIIKLKE 106
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
I E +V+EL TGG LF+ + E Y E + ++ + + +L +N +V
Sbjct: 107 IFETPTEIS--LVLELVTGGELFDRI--VEKGY-YSERDAADAVKQILEAVAYLHENGIV 161
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLKP N++ Y K+ DFG ++ ++ + ++ GT Y P+ +LR
Sbjct: 162 HRDLKPENLL-YATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPE-----ILR- 214
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
G ++G VD+WS+G+ Y + G F P+ R + MF
Sbjct: 215 --GCAYGPEVDMWSVGIITYILLCG---FEPFYDERGDQFMF 251
>L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-dependent
protein kinase protein.
Length = 473
Score = 93.9 bits (223), Expect = 1e-18
Identities = 67/222 (30%), Positives = 110/222 (49%), Gaps = 20/222 (9%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
S LG+GAT V++ K +P A+K + + + E VL ++ H NI+KL
Sbjct: 50 SELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKK---IVRTEIGVLLRLSHPNIIKLKE 106
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
I E +V+EL TGG LF+ + E Y E + ++ + + +L +N +V
Sbjct: 107 IFETPTEIS--LVLELVTGGELFDRI--VEKGY-YSERDAADAVKQILEAVAYLHENGIV 161
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLKP N++ Y K+ DFG ++ ++ + ++ GT Y P+ +LR
Sbjct: 162 HRDLKPENLL-YATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPE-----ILR- 214
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
G ++G VD+WS+G+ Y + G F P+ R + MF
Sbjct: 215 --GCAYGPEVDMWSVGIITYILLCG---FEPFYDERGDQFMF 251
>D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent protein
kinase IV protein.
Length = 473
Score = 93.9 bits (223), Expect = 1e-18
Identities = 67/222 (30%), Positives = 110/222 (49%), Gaps = 20/222 (9%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
S LG+GAT V++ K +P A+K + + + E VL ++ H NI+KL
Sbjct: 50 SELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKK---IVRTEIGVLLRLSHPNIIKLKE 106
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
I E +V+EL TGG LF+ + E Y E + ++ + + +L +N +V
Sbjct: 107 IFETPTEIS--LVLELVTGGELFDRI--VEKGY-YSERDAADAVKQILEAVAYLHENGIV 161
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLKP N++ Y K+ DFG ++ ++ + ++ GT Y P+ +LR
Sbjct: 162 HRDLKPENLL-YATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPE-----ILR- 214
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
G ++G VD+WS+G+ Y + G F P+ R + MF
Sbjct: 215 --GCAYGPEVDMWSVGIITYILLCG---FEPFYDERGDQFMF 251
>BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protein
kinase 2 protein.
Length = 370
Score = 93.9 bits (223), Expect = 1e-18
Identities = 60/184 (32%), Positives = 97/184 (52%), Gaps = 16/184 (8%)
Query: 57 REFEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFL 116
RE +L++V H N++ L + E + V+++EL +GG LF+ L E+ L E E
Sbjct: 73 REVSILRQVLHHNVITLHDVYENRTD--VVLILELVSGGELFDFLAQKES---LSEEEAT 127
Query: 117 LVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSL 176
++ + G+ +L + H DLKP NIM KL DFG A E+++ +F ++
Sbjct: 128 SFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNI 187
Query: 177 YGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETM 236
+GT E++ P++ V +P+ G D+WSIGV Y + +G PF G +ET+
Sbjct: 188 FGTPEFVAPEI----VNYEPL----GLEADMWSIGVITYILLSGASPFL---GDTKQETL 236
Query: 237 FYIT 240
IT
Sbjct: 237 ANIT 240
>BC034044-1|AAH34044.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 93.9 bits (223), Expect = 1e-18
Identities = 74/209 (35%), Positives = 100/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V K + A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCVKKTPTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + + + + H+ +++VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDIWACGVILYILLVGYPPF 214
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 93.9 bits (223), Expect = 1e-18
Identities = 67/222 (30%), Positives = 108/222 (48%), Gaps = 21/222 (9%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHEN 69
+++ +LGKG+ G V + +K A+K N + + + RE +LK VKHE+
Sbjct: 115 IYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEH 174
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
I+ L + E + +VMELC G L ILD + E E +++ L + + +L
Sbjct: 175 IIHLEQVFETP--KKMYLVMELCEDGELKEILDRKGH---FSENETRWIIQSLASAIAYL 229
Query: 130 RDNNLVHRDLKPGNIMKYI-----NEDGTTTYKLTDFGAA--RELQEEEQFVSLYGTEEY 182
+N++VHRDLK NIM N + K+TDFG A ++ + E + GT Y
Sbjct: 230 HNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIY 289
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P++ + D+WSIGV +Y + G+ PF
Sbjct: 290 MAPEVIS--------AHDYSQQCDIWSIGVVMYMLLRGEPPF 323
>BC025687-1|AAH25687.1| 473|Homo sapiens
calcium/calmodulin-dependent protein kinase IV protein.
Length = 473
Score = 93.9 bits (223), Expect = 1e-18
Identities = 67/222 (30%), Positives = 110/222 (49%), Gaps = 20/222 (9%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
S LG+GAT V++ K +P A+K + + + E VL ++ H NI+KL
Sbjct: 50 SELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKK---IVRTEIGVLLRLSHPNIIKLKE 106
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
I E +V+EL TGG LF+ + E Y E + ++ + + +L +N +V
Sbjct: 107 IFETPTEIS--LVLELVTGGELFDRI--VEKGY-YSERDAADAVKQILEAVAYLHENGIV 161
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLKP N++ Y K+ DFG ++ ++ + ++ GT Y P+ +LR
Sbjct: 162 HRDLKPENLL-YATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPE-----ILR- 214
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
G ++G VD+WS+G+ Y + G F P+ R + MF
Sbjct: 215 --GCAYGPEVDMWSVGIITYILLCG---FEPFYDERGDQFMF 251
>BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein.
Length = 503
Score = 93.9 bits (223), Expect = 1e-18
Identities = 67/222 (30%), Positives = 110/222 (49%), Gaps = 20/222 (9%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
S LG+GAT V++ K +P A+K + + + E VL ++ H NI+KL
Sbjct: 80 SELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKK---IVRTEIGVLLRLSHPNIIKLKE 136
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
I E +V+EL TGG LF+ + E Y E + ++ + + +L +N +V
Sbjct: 137 IFETPTEIS--LVLELVTGGELFDRI--VEKGY-YSERDAADAVKQILEAVAYLHENGIV 191
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLKP N++ Y K+ DFG ++ ++ + ++ GT Y P+ +LR
Sbjct: 192 HRDLKPENLL-YATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPE-----ILR- 244
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMF 237
G ++G VD+WS+G+ Y + G F P+ R + MF
Sbjct: 245 --GCAYGPEVDMWSVGIITYILLCG---FEPFYDERGDQFMF 281
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 93.9 bits (223), Expect = 1e-18
Identities = 67/222 (30%), Positives = 108/222 (48%), Gaps = 21/222 (9%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHEN 69
+++ +LGKG+ G V + +K A+K N + + + RE +LK VKHE+
Sbjct: 115 IYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEH 174
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
I+ L + E + +VMELC G L ILD + E E +++ L + + +L
Sbjct: 175 IIHLEQVFETP--KKMYLVMELCEDGELKEILDRKGH---FSENETRWIIQSLASAIAYL 229
Query: 130 RDNNLVHRDLKPGNIMKYI-----NEDGTTTYKLTDFGAA--RELQEEEQFVSLYGTEEY 182
+N++VHRDLK NIM N + K+TDFG A ++ + E + GT Y
Sbjct: 230 HNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIY 289
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P++ + D+WSIGV +Y + G+ PF
Sbjct: 290 MAPEVIS--------AHDYSQQCDIWSIGVVMYMLLRGEPPF 323
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 93.9 bits (223), Expect = 1e-18
Identities = 67/222 (30%), Positives = 108/222 (48%), Gaps = 21/222 (9%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHEN 69
+++ +LGKG+ G V + +K A+K N + + + RE +LK VKHE+
Sbjct: 115 IYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEH 174
Query: 70 IVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHL 129
I+ L + E + +VMELC G L ILD + E E +++ L + + +L
Sbjct: 175 IIHLEQVFETP--KKMYLVMELCEDGELKEILDRKGH---FSENETRWIIQSLASAIAYL 229
Query: 130 RDNNLVHRDLKPGNIMKYI-----NEDGTTTYKLTDFGAA--RELQEEEQFVSLYGTEEY 182
+N++VHRDLK NIM N + K+TDFG A ++ + E + GT Y
Sbjct: 230 HNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIY 289
Query: 183 LHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ P++ + D+WSIGV +Y + G+ PF
Sbjct: 290 MAPEVIS--------AHDYSQQCDIWSIGVVMYMLLRGEPPF 323
>AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protein
kinase 2 protein.
Length = 370
Score = 93.9 bits (223), Expect = 1e-18
Identities = 60/184 (32%), Positives = 97/184 (52%), Gaps = 16/184 (8%)
Query: 57 REFEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFL 116
RE +L++V H N++ L + E + V+++EL +GG LF+ L E+ L E E
Sbjct: 73 REVSILRQVLHHNVITLHDVYENRTD--VVLILELVSGGELFDFLAQKES---LSEEEAT 127
Query: 117 LVLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSL 176
++ + G+ +L + H DLKP NIM KL DFG A E+++ +F ++
Sbjct: 128 SFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNI 187
Query: 177 YGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETM 236
+GT E++ P++ V +P+ G D+WSIGV Y + +G PF G +ET+
Sbjct: 188 FGTPEFVAPEI----VNYEPL----GLEADMWSIGVITYILLSGASPFL---GDTKQETL 236
Query: 237 FYIT 240
IT
Sbjct: 237 ANIT 240
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 93.5 bits (222), Expect = 2e-18
Identities = 67/212 (31%), Positives = 113/212 (53%), Gaps = 24/212 (11%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQL--SHMRPHDVQMREFEVLKKVKHENIVKLL 74
++G+G+ G V++G K + + VA+K +L S ++Q RE E+++ ++H NIV +L
Sbjct: 9 MIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQ-REIEIMRGLRHPNIVHML 67
Query: 75 -AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
+ E ++E V+V+ G LF IL+D L E + + L + + +L +
Sbjct: 68 DSFETDKE----VVVVTDYAEGELFQILEDDGK---LPEDQVQAIAAQLVSALYYLHSHR 120
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAV 192
++HRD+KP NI+ + + G KL DFG AR + + S+ GT Y+ P++ E
Sbjct: 121 ILHRDMKPQNIL--LAKGGGI--KLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEE-- 174
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + T DLWS+G LY +A G PF
Sbjct: 175 ------RPYDHTADLWSVGCILYELAVGTPPF 200
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 93.5 bits (222), Expect = 2e-18
Identities = 67/212 (31%), Positives = 113/212 (53%), Gaps = 24/212 (11%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQL--SHMRPHDVQMREFEVLKKVKHENIVKLL 74
++G+G+ G V++G K + + VA+K +L S ++Q RE E+++ ++H NIV +L
Sbjct: 9 MIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQ-REIEIMRGLRHPNIVHML 67
Query: 75 -AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
+ E ++E V+V+ G LF IL+D L E + + L + + +L +
Sbjct: 68 DSFETDKE----VVVVTDYAEGELFQILEDDGK---LPEDQVQAIAAQLVSALYYLHSHR 120
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAV 192
++HRD+KP NI+ + + G KL DFG AR + + S+ GT Y+ P++ E
Sbjct: 121 ILHRDMKPQNIL--LAKGGGI--KLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEE-- 174
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + T DLWS+G LY +A G PF
Sbjct: 175 ------RPYDHTADLWSVGCILYELAVGTPPF 200
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 93.5 bits (222), Expect = 2e-18
Identities = 67/212 (31%), Positives = 113/212 (53%), Gaps = 24/212 (11%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQL--SHMRPHDVQMREFEVLKKVKHENIVKLL 74
++G+G+ G V++G K + + VA+K +L S ++Q RE E+++ ++H NIV +L
Sbjct: 26 MIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQ-REIEIMRGLRHPNIVHML 84
Query: 75 -AIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNN 133
+ E ++E V+V+ G LF IL+D L E + + L + + +L +
Sbjct: 85 DSFETDKE----VVVVTDYAEGELFQILEDDGK---LPEDQVQAIAAQLVSALYYLHSHR 137
Query: 134 LVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYERAV 192
++HRD+KP NI+ + + G KL DFG AR + + S+ GT Y+ P++ E
Sbjct: 138 ILHRDMKPQNIL--LAKGGGI--KLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEE-- 191
Query: 193 LRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + T DLWS+G LY +A G PF
Sbjct: 192 ------RPYDHTADLWSVGCILYELAVGTPPF 217
>X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase
protein.
Length = 991
Score = 93.1 bits (221), Expect = 2e-18
Identities = 66/224 (29%), Positives = 112/224 (50%), Gaps = 18/224 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG G G F+ V K + A K F S +++ +E ++ + H +V+ ++
Sbjct: 548 LGSGKFGQCFRLVEKKTRKVWAGKFFKAYSAKEKENIR-QEISIMNCLHHPKLVQ--CVD 604
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+E V+V+E+ +GG LF + D + + L E E + ++ G++++ +VH
Sbjct: 605 AFEEKANIVMVLEIVSGGELFERIIDED--FELTERECTKYMRQISEGVEYIHKQGIVHL 662
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NIM +N+ G T KL DFG R L+ L+GT E++ P++ +R
Sbjct: 663 DLKPENIM-CVNKTG-TRIKLIDFGLPRRLENAGSLKVLFGTPEFVAPEVINYEPIR--- 717
Query: 198 GKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITT 241
D+WSI V Y + +G PF P+ G + ET+ +T+
Sbjct: 718 -----YATDMWSIRVICYILVSG--PF-PFMGDNDNETLANVTS 753
>L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kinase
1 protein.
Length = 735
Score = 93.1 bits (221), Expect = 2e-18
Identities = 76/232 (32%), Positives = 119/232 (51%), Gaps = 25/232 (10%)
Query: 17 VLGKGATGAVF---QGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVK 72
VLG+G+ G VF + ++G A+K + + +R E ++L V H +VK
Sbjct: 67 VLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVK 126
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
L + EG+ ++++ GG LF L E + ++ +F L L G+ HL
Sbjct: 127 L-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALGLDHLHSL 181
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYERA 191
+++RDLKP NI+ ++E+G KLTDFG ++E + E++ S GT EY+ P++ R
Sbjct: 182 GIIYRDLKPENIL--LDEEG--HIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQ 237
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
G S A D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 238 ------GHSHSA--DWWSYGVLMFEMLTGSLPFQ---GKDRKETMTLILKAK 278
Score = 73.7 bits (173), Expect = 1e-12
Identities = 60/220 (27%), Positives = 106/220 (48%), Gaps = 22/220 (10%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK 66
S+ YV T +G G+ + V+K AVK ++ ++++ +L+ +
Sbjct: 415 SDGYVVKET--IGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEI----LLRYGQ 468
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
H NI+ L + ++ G+ +V EL GG L LD E E VL + +
Sbjct: 469 HPNIITLKDVYDD--GKHVYLVTELMRGGEL---LDKILRQKFFSEREASFVLHTIGKTV 523
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGT-TTYKLTDFGAARELQEEE-QFVSLYGTEEYLH 184
++L +VHRDLKP NI+ Y++E G ++ DFG A++L+ E ++ T ++
Sbjct: 524 EYLHSQGVVHRDLKPSNIL-YVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVA 582
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ +R + + D+WS+G+ LY + G PF
Sbjct: 583 PEVLKR--------QGYDEGCDIWSLGILLYTMLAGYTPF 614
>BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 93.1 bits (221), Expect = 2e-18
Identities = 76/232 (32%), Positives = 119/232 (51%), Gaps = 25/232 (10%)
Query: 17 VLGKGATGAVF---QGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVK 72
VLG+G+ G VF + ++G A+K + + +R E ++L V H +VK
Sbjct: 67 VLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVK 126
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
L + EG+ ++++ GG LF L E + ++ +F L L G+ HL
Sbjct: 127 L-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALGLDHLHSL 181
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYERA 191
+++RDLKP NI+ ++E+G KLTDFG ++E + E++ S GT EY+ P++ R
Sbjct: 182 GIIYRDLKPENIL--LDEEG--HIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQ 237
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
G S A D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 238 ------GHSHSA--DWWSYGVLMFEMLTGSLPFQ---GKDRKETMTLILKAK 278
Score = 73.7 bits (173), Expect = 1e-12
Identities = 60/220 (27%), Positives = 106/220 (48%), Gaps = 22/220 (10%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK 66
S+ YV T +G G+ + V+K AVK ++ ++++ +L+ +
Sbjct: 415 SDGYVVKET--IGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEI----LLRYGQ 468
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
H NI+ L + ++ G+ +V EL GG L LD E E VL + +
Sbjct: 469 HPNIITLKDVYDD--GKHVYLVTELMRGGEL---LDKILRQKFFSEREASFVLHTIGKTV 523
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGT-TTYKLTDFGAARELQEEE-QFVSLYGTEEYLH 184
++L +VHRDLKP NI+ Y++E G ++ DFG A++L+ E ++ T ++
Sbjct: 524 EYLHSQGVVHRDLKPSNIL-YVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVA 582
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ +R + + D+WS+G+ LY + G PF
Sbjct: 583 PEVLKR--------QGYDEGCDIWSLGILLYTMLAGYTPF 614
>AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 93.1 bits (221), Expect = 2e-18
Identities = 76/232 (32%), Positives = 119/232 (51%), Gaps = 25/232 (10%)
Query: 17 VLGKGATGAVF---QGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVK 72
VLG+G+ G VF + ++G A+K + + +R E ++L V H +VK
Sbjct: 67 VLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVK 126
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
L + EG+ ++++ GG LF L E + ++ +F L L G+ HL
Sbjct: 127 L-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALGLDHLHSL 181
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYERA 191
+++RDLKP NI+ ++E+G KLTDFG ++E + E++ S GT EY+ P++ R
Sbjct: 182 GIIYRDLKPENIL--LDEEG--HIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQ 237
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
G S A D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 238 ------GHSHSA--DWWSYGVLMFEMLTGSLPFQ---GKDRKETMTLILKAK 278
Score = 73.7 bits (173), Expect = 1e-12
Identities = 60/220 (27%), Positives = 106/220 (48%), Gaps = 22/220 (10%)
Query: 7 SENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK 66
S+ YV T +G G+ + V+K AVK ++ ++++ +L+ +
Sbjct: 415 SDGYVVKET--IGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEI----LLRYGQ 468
Query: 67 HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGM 126
H NI+ L + ++ G+ +V EL GG L LD E E VL + +
Sbjct: 469 HPNIITLKDVYDD--GKHVYLVTELMRGGEL---LDKILRQKFFSEREASFVLHTIGKTV 523
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGT-TTYKLTDFGAARELQEEE-QFVSLYGTEEYLH 184
++L +VHRDLKP NI+ Y++E G ++ DFG A++L+ E ++ T ++
Sbjct: 524 EYLHSQGVVHRDLKPSNIL-YVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVA 582
Query: 185 PDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
P++ +R + + D+WS+G+ LY + G PF
Sbjct: 583 PEVLKR--------QGYDEGCDIWSLGILLYTMLAGYTPF 614
>BC032784-1|AAH32784.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II delta protein.
Length = 478
Score = 92.7 bits (220), Expect = 3e-18
Identities = 73/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + + G+ A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H N +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILESVNHCHLNGIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKSKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDMWACGVILYILLVGYPPF 214
>AY987011-1|AAX88806.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
protein.
Length = 489
Score = 92.7 bits (220), Expect = 3e-18
Identities = 73/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + + G+ A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H N +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILESVNHCHLNGIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKSKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDMWACGVILYILLVGYPPF 214
>AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin
dependent protein kinase II delta protein.
Length = 243
Score = 92.7 bits (220), Expect = 3e-18
Identities = 73/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + + G+ A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H N +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILESVNHCHLNGIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKSKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDMWACGVILYILLVGYPPF 214
>AB209288-1|BAD92525.1| 522|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
isoform 1 variant protein.
Length = 522
Score = 92.7 bits (220), Expect = 3e-18
Identities = 73/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + + G+ A K N R H RE + + +KH NIV+L
Sbjct: 50 LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 109
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H N +VH
Sbjct: 110 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILESVNHCHLNGIVH 164
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 165 RDLKPENLLLASKSKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 218
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 219 ---DPYGKPVDMWACGVILYILLVGYPPF 244
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 92.3 bits (219), Expect = 4e-18
Identities = 61/215 (28%), Positives = 102/215 (47%), Gaps = 16/215 (7%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHENI 70
+ +G+GA G + K++ + +K N + ++ + +E +L+K+KH NI
Sbjct: 4 YDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPNI 63
Query: 71 VKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLR 130
V QE IVME C GG L ++ E + L ++ G+KH+
Sbjct: 64 VAFF--NSFQENGRLFIVMEYCDGGDLMKRINRQRGVL-FSEDQILGWFVQISLGLKHIH 120
Query: 131 DNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYE 189
D ++HRD+K NI +++++G KL DFG AR L + + GT YL P++ +
Sbjct: 121 DRKILHRDIKAQNI--FLSKNGMVA-KLGDFGIARVLNNSMELARTCIGTPYYLSPEICQ 177
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + D+WS+G LY + T + PF
Sbjct: 178 --------NKPYNNKTDIWSLGCVLYELCTLKHPF 204
>BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein.
Length = 247
Score = 92.3 bits (219), Expect = 4e-18
Identities = 61/218 (27%), Positives = 109/218 (50%), Gaps = 15/218 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVK-HENI 70
W T +GKG G VF+ +NK NG+ AVK + + H +++ + +LK + H N+
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIE-AGYNILKALSDHPNV 78
Query: 71 VKLLAI---EEEQEGRGKVIVMELCTGGSLFNILDD-PENTYGLQEYEFLLVLEHLTAGM 126
V+ I +++ G +V+ELC+GGS+ +++ + + E +L G+
Sbjct: 79 VRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGL 138
Query: 127 KHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAAREL-QEEEQFVSLYGTEEYLHP 185
+HL +N +HRD+K NI+ E G KL DFG + +L + + GT ++ P
Sbjct: 139 QHLHNNKTIHRDVKGNNIL-LTTEGGV---KLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
++ + + ++ A D WS+G+T + G P
Sbjct: 195 EV---IACEQQLDTTYDARCDTWSLGITAIELGDGDPP 229
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 92.3 bits (219), Expect = 4e-18
Identities = 61/215 (28%), Positives = 102/215 (47%), Gaps = 16/215 (7%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHENI 70
+ +G+GA G + K++ + +K N + ++ + +E +L+K+KH NI
Sbjct: 4 YDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPNI 63
Query: 71 VKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLR 130
V QE IVME C GG L ++ E + L ++ G+KH+
Sbjct: 64 VAFF--NSFQENGRLFIVMEYCDGGDLMKRINRQRGVL-FSEDQILGWFVQISLGLKHIH 120
Query: 131 DNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-SLYGTEEYLHPDMYE 189
D ++HRD+K NI +++++G KL DFG AR L + + GT YL P++ +
Sbjct: 121 DRKILHRDIKAQNI--FLSKNGMVA-KLGDFGIARVLNNSMELARTCIGTPYYLSPEICQ 177
Query: 190 RAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + D+WS+G LY + T + PF
Sbjct: 178 --------NKPYNNKTDIWSLGCVLYELCTLKHPF 204
>AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional
calcium/calmodulin-dependent protein kinase II delta2
isoform protein.
Length = 499
Score = 92.3 bits (219), Expect = 4e-18
Identities = 73/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + + G+ A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCMKIPTGQGYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H N +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILESVNHCHLNGIVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKSKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 ---DPYGKPVDMWACGVILYILLVGYPPF 214
>AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein.
Length = 890
Score = 92.3 bits (219), Expect = 4e-18
Identities = 65/209 (31%), Positives = 105/209 (50%), Gaps = 14/209 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLA 75
VLG G G V+ G ++ G VA+K +++ + Q+R E +L+ + H IV L
Sbjct: 581 VLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLHHPGIVNLEC 640
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E E +VME G L IL ++ + +F++ + +++L N+V
Sbjct: 641 MFETPER--VFVVMEKLHGDMLEMILSSEKSRLPERITKFMVT--QILVALRNLHFKNIV 696
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
H DLKP N++ + + KL DFG AR + E+ S+ GT YL P+ VLR
Sbjct: 697 HCDLKPENVL-LASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPE-----VLRS 750
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + ++D+WS+GV +Y +G PF
Sbjct: 751 ---KGYNRSLDMWSVGVIIYVSLSGTFPF 776
>AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase
protein.
Length = 890
Score = 92.3 bits (219), Expect = 4e-18
Identities = 65/209 (31%), Positives = 105/209 (50%), Gaps = 14/209 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMR-EFEVLKKVKHENIVKLLA 75
VLG G G V+ G ++ G VA+K +++ + Q+R E +L+ + H IV L
Sbjct: 581 VLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLHHPGIVNLEC 640
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
+ E E +VME G L IL ++ + +F++ + +++L N+V
Sbjct: 641 MFETPER--VFVVMEKLHGDMLEMILSSEKSRLPERITKFMVT--QILVALRNLHFKNIV 696
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
H DLKP N++ + + KL DFG AR + E+ S+ GT YL P+ VLR
Sbjct: 697 HCDLKPENVL-LASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPE-----VLRS 750
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
K + ++D+WS+GV +Y +G PF
Sbjct: 751 ---KGYNRSLDMWSVGVIIYVSLSGTFPF 776
>U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase
kinase kinase 5 protein.
Length = 1374
Score = 91.9 bits (218), Expect = 5e-18
Identities = 66/213 (30%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G + +N +A+K + + E + K +KH+NIV+ L
Sbjct: 685 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKHLKHKNIVQYLGS 743
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E G K+ ME GGSL +L E + + G+K+L DN +VH
Sbjct: 744 FSEN-GFIKIF-MEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVH 801
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 802 RDIKGDNVL--INTY-SGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKG---- 854
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 855 PRG--YGKAADIWSLGCTIIEMATGKPPFYELG 885
>D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulating
kinase 1 protein.
Length = 1374
Score = 91.9 bits (218), Expect = 5e-18
Identities = 66/213 (30%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G + +N +A+K + + E + K +KH+NIV+ L
Sbjct: 685 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKHLKHKNIVQYLGS 743
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E G K+ ME GGSL +L E + + G+K+L DN +VH
Sbjct: 744 FSEN-GFIKIF-MEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVH 801
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 802 RDIKGDNVL--INTY-SGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKG---- 854
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 855 PRG--YGKAADIWSLGCTIIEMATGKPPFYELG 885
>BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 91.9 bits (218), Expect = 5e-18
Identities = 66/213 (30%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G + +N +A+K + + E + K +KH+NIV+ L
Sbjct: 685 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKHLKHKNIVQYLGS 743
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E G K+ ME GGSL +L E + + G+K+L DN +VH
Sbjct: 744 FSEN-GFIKIF-MEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVH 801
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 802 RDIKGDNVL--INTY-SGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKG---- 854
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 855 PRG--YGKAADIWSLGCTIIEMATGKPPFYELG 885
>BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 91.9 bits (218), Expect = 5e-18
Identities = 66/213 (30%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G + +N +A+K + + E + K +KH+NIV+ L
Sbjct: 685 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKHLKHKNIVQYLGS 743
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E G K+ ME GGSL +L E + + G+K+L DN +VH
Sbjct: 744 FSEN-GFIKIF-MEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVH 801
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 802 RDIKGDNVL--INTY-SGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKG---- 854
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 855 PRG--YGKAADIWSLGCTIIEMATGKPPFYELG 885
>AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein
protein.
Length = 716
Score = 91.9 bits (218), Expect = 5e-18
Identities = 60/209 (28%), Positives = 103/209 (49%), Gaps = 15/209 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
V+G G V + ++++ G+ A+K ++ + E +L++VKH NI+ L +
Sbjct: 349 VIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIML--V 406
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
EE + +VMEL GG LF+ + E + ++ +L +++L ++VH
Sbjct: 407 EEMETATELFLVMELVKGGDLFDAITSSTK---YTERDGSAMVYNLANALRYLHGLSIVH 463
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RD+KP N++ DGT + KL DFG A + E ++ GT Y+ P++
Sbjct: 464 RDIKPENLLVCEYPDGTKSLKLGDFGLATVV--EGPLYTVCGTPTYVAPEIIAET----- 516
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+G VD+W+ GV Y + G PFR
Sbjct: 517 ---GYGLKVDIWAAGVITYILLCGFPPFR 542
>AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 91.9 bits (218), Expect = 5e-18
Identities = 66/213 (30%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G + +N +A+K + + E + K +KH+NIV+ L
Sbjct: 685 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKHLKHKNIVQYLGS 743
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E G K+ ME GGSL +L E + + G+K+L DN +VH
Sbjct: 744 FSEN-GFIKIF-MEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVH 801
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 802 RDIKGDNVL--INTY-SGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKG---- 854
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 855 PRG--YGKAADIWSLGCTIIEMATGKPPFYELG 885
>AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 91.9 bits (218), Expect = 5e-18
Identities = 66/213 (30%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G + +N +A+K + + E + K +KH+NIV+ L
Sbjct: 685 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKHLKHKNIVQYLGS 743
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E G K+ ME GGSL +L E + + G+K+L DN +VH
Sbjct: 744 FSEN-GFIKIF-MEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVH 801
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 802 RDIKGDNVL--INTY-SGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKG---- 854
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 855 PRG--YGKAADIWSLGCTIIEMATGKPPFYELG 885
>AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein.
Length = 443
Score = 91.9 bits (218), Expect = 5e-18
Identities = 60/209 (28%), Positives = 103/209 (49%), Gaps = 15/209 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
V+G G V + ++++ G+ A+K ++ + E +L++VKH NI+ L +
Sbjct: 146 VIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIML--V 203
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
EE + +VMEL GG LF+ + E + ++ +L +++L ++VH
Sbjct: 204 EEMETATELFLVMELVKGGDLFDAITSSTK---YTERDGSAMVYNLANALRYLHGLSIVH 260
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RD+KP N++ DGT + KL DFG A + E ++ GT Y+ P++
Sbjct: 261 RDIKPENLLVCEYPDGTKSLKLGDFGLATVV--EGPLYTVCGTPTYVAPEIIAET----- 313
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+G VD+W+ GV Y + G PFR
Sbjct: 314 ---GYGLKVDIWAAGVITYILLCGFPPFR 339
>AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein
DKFZp761I032 variant protein.
Length = 796
Score = 91.9 bits (218), Expect = 5e-18
Identities = 60/209 (28%), Positives = 103/209 (49%), Gaps = 15/209 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
V+G G V + ++++ G+ A+K ++ + E +L++VKH NI+ L +
Sbjct: 429 VIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIML--V 486
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
EE + +VMEL GG LF+ + E + ++ +L +++L ++VH
Sbjct: 487 EEMETATELFLVMELVKGGDLFDAITSSTK---YTERDGSAMVYNLANALRYLHGLSIVH 543
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKP 196
RD+KP N++ DGT + KL DFG A + E ++ GT Y+ P++
Sbjct: 544 RDIKPENLLVCEYPDGTKSLKLGDFGLATVV--EGPLYTVCGTPTYVAPEIIAET----- 596
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPFR 225
+G VD+W+ GV Y + G PFR
Sbjct: 597 ---GYGLKVDIWAAGVITYILLCGFPPFR 622
>AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 variant protein.
Length = 1455
Score = 91.9 bits (218), Expect = 5e-18
Identities = 66/213 (30%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G + +N +A+K + + E + K +KH+NIV+ L
Sbjct: 765 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKHLKHKNIVQYLGS 823
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E G K+ ME GGSL +L E + + G+K+L DN +VH
Sbjct: 824 FSEN-GFIKIF-MEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVH 881
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 882 RDIKGDNVL--INTY-SGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKG---- 934
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 935 PRG--YGKAADIWSLGCTIIEMATGKPPFYELG 965
>BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 91.5 bits (217), Expect = 7e-18
Identities = 63/211 (29%), Positives = 112/211 (53%), Gaps = 17/211 (8%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
+++G G+ V + K +P A+K + + + E VL++V H IV+L+
Sbjct: 67 ALIGTGSFSRVVRVEQKTTKKPFAIKVM-ETREREGREACVSELSVLRRVSHRYIVQLME 125
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
I E ++ +VMEL TGG LF+ L + E + + +L+ + G+++L +
Sbjct: 126 IFETEDQ--VYMVMELATGGELFDRLIAQGS---FTERDAVRILQMVADGIRYLHALQIT 180
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV--SLYGTEEYLHPDMYERAVL 193
HR+LKP N++ Y + + +TDFG A ++ + +L GT EY+ P++ +L
Sbjct: 181 HRNLKPENLL-YYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEV----LL 235
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
RKP + + VD+W++GV Y + +G LPF
Sbjct: 236 RKP----YTSAVDMWALGVITYALLSGFLPF 262
>BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 91.5 bits (217), Expect = 7e-18
Identities = 63/211 (29%), Positives = 112/211 (53%), Gaps = 17/211 (8%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
+++G G+ V + K +P A+K + + + E VL++V H IV+L+
Sbjct: 67 ALIGTGSFSRVVRVEQKTTKKPFAIKVM-ETREREGREACVSELSVLRRVSHRYIVQLME 125
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
I E ++ +VMEL TGG LF+ L + E + + +L+ + G+++L +
Sbjct: 126 IFETEDQ--VYMVMELATGGELFDRLIAQGS---FTERDAVRILQMVADGIRYLHALQIT 180
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV--SLYGTEEYLHPDMYERAVL 193
HR+LKP N++ Y + + +TDFG A ++ + +L GT EY+ P++ +L
Sbjct: 181 HRNLKPENLL-YYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEV----LL 235
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
RKP + + VD+W++GV Y + +G LPF
Sbjct: 236 RKP----YTSAVDMWALGVITYALLSGFLPF 262
>AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase
PSKH2 protein.
Length = 385
Score = 91.5 bits (217), Expect = 7e-18
Identities = 63/211 (29%), Positives = 112/211 (53%), Gaps = 17/211 (8%)
Query: 16 SVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLA 75
+++G G+ V + K +P A+K + + + E VL++V H IV+L+
Sbjct: 67 ALIGTGSFSRVVRVEQKTTKKPFAIKVM-ETREREGREACVSELSVLRRVSHRYIVQLME 125
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLV 135
I E ++ +VMEL TGG LF+ L + E + + +L+ + G+++L +
Sbjct: 126 IFETEDQ--VYMVMELATGGELFDRLIAQGS---FTERDAVRILQMVADGIRYLHALQIT 180
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV--SLYGTEEYLHPDMYERAVL 193
HR+LKP N++ Y + + +TDFG A ++ + +L GT EY+ P++ +L
Sbjct: 181 HRNLKPENLL-YYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEV----LL 235
Query: 194 RKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
RKP + + VD+W++GV Y + +G LPF
Sbjct: 236 RKP----YTSAVDMWALGVITYALLSGFLPF 262
>AF112472-1|AAD03744.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 91.5 bits (217), Expect = 7e-18
Identities = 73/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + VKH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLVKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILXAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>AF112471-1|AAD03743.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 517
Score = 91.5 bits (217), Expect = 7e-18
Identities = 73/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + VKH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLVKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILXAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 91.1 bits (216), Expect = 9e-18
Identities = 67/217 (30%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG+GA G V VN+ E VAVK + + + +E + K + HEN+V
Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVV 68
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
K +EG + + +E C+GG LF D E G+ E + L AG+ +L
Sbjct: 69 KFYG--HRREGNIQYLFLEYCSGGELF---DRIEPDIGMPEPDAQRFFHQLMAGVVYLHG 123
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAA---RELQEEEQFVSLYGTEEYLHPDMY 188
+ HRD+KP N++ D K++DFG A R E + GT Y+ P++
Sbjct: 124 IGITHRDIKPENLLL----DERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELL 179
Query: 189 ERAVLRKPVGKSFGA-TVDLWSIGVTLYHVATGQLPF 224
+R + F A VD+WS G+ L + G+LP+
Sbjct: 180 KR--------REFHAEPVDVWSCGIVLTAMLAGELPW 208
>BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein.
Length = 476
Score = 91.1 bits (216), Expect = 9e-18
Identities = 67/217 (30%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG+GA G V VN+ E VAVK + + + +E + K + HEN+V
Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVV 68
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
K +EG + + +E C+GG LF D E G+ E + L AG+ +L
Sbjct: 69 KFYG--HRREGNIQYLFLEYCSGGELF---DRIEPDIGMPEPDAQRFFHQLMAGVVYLHG 123
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAA---RELQEEEQFVSLYGTEEYLHPDMY 188
+ HRD+KP N++ D K++DFG A R E + GT Y+ P++
Sbjct: 124 IGITHRDIKPENLLL----DERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELL 179
Query: 189 ERAVLRKPVGKSFGA-TVDLWSIGVTLYHVATGQLPF 224
+R + F A VD+WS G+ L + G+LP+
Sbjct: 180 KR--------REFHAEPVDVWSCGIVLTAMLAGELPW 208
>AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 91.1 bits (216), Expect = 9e-18
Identities = 67/217 (30%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG+GA G V VN+ E VAVK + + + +E + K + HEN+V
Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVV 68
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
K +EG + + +E C+GG LF D E G+ E + L AG+ +L
Sbjct: 69 KFYG--HRREGNIQYLFLEYCSGGELF---DRIEPDIGMPEPDAQRFFHQLMAGVVYLHG 123
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAA---RELQEEEQFVSLYGTEEYLHPDMY 188
+ HRD+KP N++ D K++DFG A R E + GT Y+ P++
Sbjct: 124 IGITHRDIKPENLLL----DERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELL 179
Query: 189 ERAVLRKPVGKSFGA-TVDLWSIGVTLYHVATGQLPF 224
+R + F A VD+WS G+ L + G+LP+
Sbjct: 180 KR--------REFHAEPVDVWSCGIVLTAMLAGELPW 208
>AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kinase
isoform 3B protein.
Length = 1793
Score = 91.1 bits (216), Expect = 9e-18
Identities = 61/198 (30%), Positives = 103/198 (52%), Gaps = 16/198 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG G G VF+ V K + A K F S +++ +E ++ + H +V+ ++
Sbjct: 1401 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIR-QEITIMNCLHHPKLVQ--CVD 1457
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+E V+V+E+ +GG LF + D + + L E E + + ++ G++++ +VH
Sbjct: 1458 AFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYIHKQGIVHL 1515
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NIM +N+ G T KL DFG AR L+ L+GT E++ P++ + +P+
Sbjct: 1516 DLKPENIM-CVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEV----INYEPI 1569
Query: 198 GKSFGATVDLWSIGVTLY 215
D+WSIGV Y
Sbjct: 1570 D-----ATDMWSIGVICY 1582
>AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kinase
isoform 3A protein.
Length = 1862
Score = 91.1 bits (216), Expect = 9e-18
Identities = 61/198 (30%), Positives = 103/198 (52%), Gaps = 16/198 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
LG G G VF+ V K + A K F S +++ +E ++ + H +V+ ++
Sbjct: 1470 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIR-QEITIMNCLHHPKLVQ--CVD 1526
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
+E V+V+E+ +GG LF + D + + L E E + + ++ G++++ +VH
Sbjct: 1527 AFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYIHKQGIVHL 1584
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRKPV 197
DLKP NIM +N+ G T KL DFG AR L+ L+GT E++ P++ + +P+
Sbjct: 1585 DLKPENIM-CVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEV----INYEPI 1638
Query: 198 GKSFGATVDLWSIGVTLY 215
D+WSIGV Y
Sbjct: 1639 D-----ATDMWSIGVICY 1651
>AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein.
Length = 476
Score = 91.1 bits (216), Expect = 9e-18
Identities = 67/217 (30%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG+GA G V VN+ E VAVK + + + +E + K + HEN+V
Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVV 68
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
K +EG + + +E C+GG LF D E G+ E + L AG+ +L
Sbjct: 69 KFYG--HRREGNIQYLFLEYCSGGELF---DRIEPDIGMPEPDAQRFFHQLMAGVVYLHG 123
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAA---RELQEEEQFVSLYGTEEYLHPDMY 188
+ HRD+KP N++ D K++DFG A R E + GT Y+ P++
Sbjct: 124 IGITHRDIKPENLLL----DERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELL 179
Query: 189 ERAVLRKPVGKSFGA-TVDLWSIGVTLYHVATGQLPF 224
+R + F A VD+WS G+ L + G+LP+
Sbjct: 180 KR--------REFHAEPVDVWSCGIVLTAMLAGELPW 208
>AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein.
Length = 476
Score = 91.1 bits (216), Expect = 9e-18
Identities = 67/217 (30%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG+GA G V VN+ E VAVK + + + +E + K + HEN+V
Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVV 68
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
K +EG + + +E C+GG LF D E G+ E + L AG+ +L
Sbjct: 69 KFYG--HRREGNIQYLFLEYCSGGELF---DRIEPDIGMPEPDAQRFFHQLMAGVVYLHG 123
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAA---RELQEEEQFVSLYGTEEYLHPDMY 188
+ HRD+KP N++ D K++DFG A R E + GT Y+ P++
Sbjct: 124 IGITHRDIKPENLLL----DERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELL 179
Query: 189 ERAVLRKPVGKSFGA-TVDLWSIGVTLYHVATGQLPF 224
+R + F A VD+WS G+ L + G+LP+
Sbjct: 180 KR--------REFHAEPVDVWSCGIVLTAMLAGELPW 208
>AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein.
Length = 476
Score = 91.1 bits (216), Expect = 9e-18
Identities = 67/217 (30%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG+GA G V VN+ E VAVK + + + +E + K + HEN+V
Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVV 68
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
K +EG + + +E C+GG LF D E G+ E + L AG+ +L
Sbjct: 69 KFYG--HRREGNIQYLFLEYCSGGELF---DRIEPDIGMPEPDAQRFFHQLMAGVVYLHG 123
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAA---RELQEEEQFVSLYGTEEYLHPDMY 188
+ HRD+KP N++ D K++DFG A R E + GT Y+ P++
Sbjct: 124 IGITHRDIKPENLLL----DERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELL 179
Query: 189 ERAVLRKPVGKSFGA-TVDLWSIGVTLYHVATGQLPF 224
+R + F A VD+WS G+ L + G+LP+
Sbjct: 180 KR--------REFHAEPVDVWSCGIVLTAMLAGELPW 208
>D86968-1|BAA13204.2| 1626|Homo sapiens KIAA0213 protein.
Length = 1626
Score = 90.6 bits (215), Expect = 1e-17
Identities = 62/224 (27%), Positives = 109/224 (48%), Gaps = 22/224 (9%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHE 68
+ W + +G+G G V+ ++ + GE +A+K Q + + E ++ + +KH
Sbjct: 1359 FKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHP 1418
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
N+V+ +E +E I ME C G+L + + GLQE+ L + +T +
Sbjct: 1419 NLVRYFGVELHREEM--YIFMEYCDEGTLEEV-----SRLGLQEHVIRLYSKQITIAINV 1471
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-----SLYGTEEYL 183
L ++ +VHRD+K NI ++ G KL DFG + +L+ Q + S GT Y+
Sbjct: 1472 LHEHGIVHRDIKGANI--FLTSSG--LIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYM 1527
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPY 227
P++ RA G+ G D+WS+G + + TG+ P+ Y
Sbjct: 1528 APEVITRA-----KGEGHGRAADIWSLGCVVIEMVTGKRPWHEY 1566
>BC040457-1|AAH40457.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II alpha protein.
Length = 478
Score = 90.6 bits (215), Expect = 1e-17
Identities = 73/209 (34%), Positives = 98/209 (46%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V G+ A K N R H RE + + +KH NIV+L
Sbjct: 19 LGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 78
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG ++ +L TGG LF D Y E + ++ + + H +VH
Sbjct: 79 ISE-EGH-HYLIFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 133
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E++ E+Q + GT YL P+ VLRK
Sbjct: 134 RDLKPENLLLASKLKGAAV-KLADFGLAIEVEGEQQAWFGFAGTPGYLSPE-----VLRK 187
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VDLW+ GV LY + G PF
Sbjct: 188 D---PYGKPVDLWACGVILYILLVGYPPF 213
>AF145711-1|AAD30559.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha-B
subunit protein.
Length = 489
Score = 90.6 bits (215), Expect = 1e-17
Identities = 73/209 (34%), Positives = 98/209 (46%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V G+ A K N R H RE + + +KH NIV+L
Sbjct: 19 LGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 78
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG ++ +L TGG LF D Y E + ++ + + H +VH
Sbjct: 79 ISE-EGH-HYLIFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 133
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E++ E+Q + GT YL P+ VLRK
Sbjct: 134 RDLKPENLLLASKLKGAAV-KLADFGLAIEVEGEQQAWFGFAGTPGYLSPE-----VLRK 187
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VDLW+ GV LY + G PF
Sbjct: 188 D---PYGKPVDLWACGVILYILLVGYPPF 213
>AF145710-1|AAD30558.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha
subunit protein.
Length = 478
Score = 90.6 bits (215), Expect = 1e-17
Identities = 73/209 (34%), Positives = 98/209 (46%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V G+ A K N R H RE + + +KH NIV+L
Sbjct: 19 LGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 78
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG ++ +L TGG LF D Y E + ++ + + H +VH
Sbjct: 79 ISE-EGH-HYLIFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 133
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E++ E+Q + GT YL P+ VLRK
Sbjct: 134 RDLKPENLLLASKLKGAAV-KLADFGLAIEVEGEQQAWFGFAGTPGYLSPE-----VLRK 187
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VDLW+ GV LY + G PF
Sbjct: 188 D---PYGKPVDLWACGVILYILLVGYPPF 213
>AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent
protein kinase II alpha protein.
Length = 478
Score = 90.6 bits (215), Expect = 1e-17
Identities = 73/209 (34%), Positives = 98/209 (46%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V G+ A K N R H RE + + +KH NIV+L
Sbjct: 19 LGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 78
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG ++ +L TGG LF D Y E + ++ + + H +VH
Sbjct: 79 ISE-EGH-HYLIFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 133
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E++ E+Q + GT YL P+ VLRK
Sbjct: 134 RDLKPENLLLASKLKGAAV-KLADFGLAIEVEGEQQAWFGFAGTPGYLSPE-----VLRK 187
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VDLW+ GV LY + G PF
Sbjct: 188 D---PYGKPVDLWACGVILYILLVGYPPF 213
>AF002715-1|AAB68804.1| 1607|Homo sapiens MAP kinase kinase kinase
protein.
Length = 1607
Score = 90.6 bits (215), Expect = 1e-17
Identities = 62/224 (27%), Positives = 109/224 (48%), Gaps = 22/224 (9%)
Query: 10 YVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFN-QLSHMRPHDVQMREFEVLKKVKHE 68
+ W + +G+G G V+ ++ + GE +A+K Q + + E ++ + +KH
Sbjct: 1340 FKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHP 1399
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
N+V+ +E +E I ME C G+L + + GLQE+ L + +T +
Sbjct: 1400 NLVRYFGVELHREEM--YIFMEYCDEGTLEEV-----SRLGLQEHVIRLYSKQITIAINV 1452
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV-----SLYGTEEYL 183
L ++ +VHRD+K NI ++ G KL DFG + +L+ Q + S GT Y+
Sbjct: 1453 LHEHGIVHRDIKGANI--FLTSSG--LIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYM 1508
Query: 184 HPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPY 227
P++ RA G+ G D+WS+G + + TG+ P+ Y
Sbjct: 1509 APEVITRA-----KGEGHGRAADIWSLGCVVIEMVTGKRPWHEY 1547
>AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein.
Length = 527
Score = 90.6 bits (215), Expect = 1e-17
Identities = 73/209 (34%), Positives = 98/209 (46%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + V G+ A K N R H RE + + +KH NIV+L
Sbjct: 68 LGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 127
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG ++ +L TGG LF D Y E + ++ + + H +VH
Sbjct: 128 ISE-EGH-HYLIFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 182
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E++ E+Q + GT YL P+ VLRK
Sbjct: 183 RDLKPENLLLASKLKGAAV-KLADFGLAIEVEGEQQAWFGFAGTPGYLSPE-----VLRK 236
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VDLW+ GV LY + G PF
Sbjct: 237 D---PYGKPVDLWACGVILYILLVGYPPF 262
>U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kinase
protein.
Length = 525
Score = 90.2 bits (214), Expect = 2e-17
Identities = 60/208 (28%), Positives = 107/208 (51%), Gaps = 19/208 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G+GA+G VF + G+ VA+K N L ++ + E V+K++K+ NIV L +
Sbjct: 255 IGQGASGTVFTATDVALGQEVAIKQIN-LQKQPKKELIINEILVMKELKNPNIVNFL--D 311
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
G +VME GGSL +++ + T + E + V ++ L N ++HR
Sbjct: 312 SYLVGDELFVVMEYLAGGSLTDVVTE---TACMDEAQIAAVCRECLQALEFLHANQVIHR 368
Query: 138 DLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVS-LYGTEEYLHPDMYERAVLRKP 196
D+K N++ + +G+ KLTDFG ++ E+ S + GT ++ P++ R
Sbjct: 369 DIKSDNVL--LGMEGSV--KLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTR------ 418
Query: 197 VGKSFGATVDLWSIGVTLYHVATGQLPF 224
K++G VD+WS+G+ + G+ P+
Sbjct: 419 --KAYGPKVDIWSLGIMAIEMVEGEPPY 444
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 90.2 bits (214), Expect = 2e-17
Identities = 61/210 (29%), Positives = 101/210 (48%), Gaps = 19/210 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+G G V G++ E VA+K ++ + + RE ++K+ H NI++L +
Sbjct: 80 IGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEV 139
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNLV 135
E +VME GG LF + +T G L E E L+ + + +KH+ +N ++
Sbjct: 140 VETLSKLH--LVMEYAGGGELFGKI----STEGKLSEPESKLIFSQIVSAVKHMHENQII 193
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLRK 195
HRDLK N+ N T K+ DFG + ++ E + G+ Y P+++
Sbjct: 194 HRDLKAENVFYTSN----TCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDE---- 245
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFR 225
G VD+W++GV LY + TG +PFR
Sbjct: 246 ---HYIGIYVDIWALGVLLYFMVTGTMPFR 272
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 89.8 bits (213), Expect = 2e-17
Identities = 64/219 (29%), Positives = 107/219 (48%), Gaps = 20/219 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVK------TFNQLSHMRPHDVQMREFEVLKKV 65
+ T LG G V + K+ G A K T + + D++ RE +LK++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIE-REVSILKEI 71
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
+H N++ L + E + ++++EL GG LF+ L + E+ L E E L+ + G
Sbjct: 72 QHPNVITLHEVYENKTD--VILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNG 126
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
+ +L + H DLKP NIM K+ DFG A ++ +F +++GT E++ P
Sbjct: 127 VYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAP 186
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ V +P+ G D+WSIGV Y + +G PF
Sbjct: 187 EI----VNYEPL----GLEADMWSIGVITYILLSGASPF 217
>U23460-1|AAC99802.1| 664|Homo sapiens proline rich
calmodulin-dependent protein kinase protein.
Length = 664
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + +KH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 89.8 bits (213), Expect = 2e-17
Identities = 64/219 (29%), Positives = 107/219 (48%), Gaps = 20/219 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVK------TFNQLSHMRPHDVQMREFEVLKKV 65
+ T LG G V + K+ G A K T + + D++ RE +LK++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIE-REVSILKEI 71
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
+H N++ L + E + ++++EL GG LF+ L + E+ L E E L+ + G
Sbjct: 72 QHPNVITLHEVYENKTD--VILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNG 126
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
+ +L + H DLKP NIM K+ DFG A ++ +F +++GT E++ P
Sbjct: 127 VYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAP 186
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ V +P+ G D+WSIGV Y + +G PF
Sbjct: 187 EI----VNYEPL----GLEADMWSIGVITYILLSGASPF 217
>CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein.
Length = 586
Score = 89.8 bits (213), Expect = 2e-17
Identities = 69/224 (30%), Positives = 106/224 (47%), Gaps = 21/224 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ----LSHMRPHDVQMR---EFE 60
+ Y+ S T LG GA G V + + VA+K ++ + R D + E E
Sbjct: 261 DEYIMSKT--LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 318
Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
+LKK+ H I+K+ + ++ IV+EL GG LF D L+E L
Sbjct: 319 ILKKLNHPCIIKIKNFFDAED---YYIVLELMEGGELF---DKVVGNKRLKEATCKLYFY 372
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +++L +N ++HRDLKP N++ E+ K+TDFG ++ L E +L GT
Sbjct: 373 QMLLAVQYLHENGIIHRDLKPENVLLSSQEE-DCLIKITDFGHSKILGETSLMRTLCGTP 431
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
YL P+ VL + VD WS+GV L+ +G PF
Sbjct: 432 TYLAPE-----VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF 470
>BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protein
kinase 1 protein.
Length = 367
Score = 89.8 bits (213), Expect = 2e-17
Identities = 64/219 (29%), Positives = 107/219 (48%), Gaps = 20/219 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVK------TFNQLSHMRPHDVQMREFEVLKKV 65
+ T LG G V + K+ G A K T + + D++ RE +LK++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIE-REVSILKEI 71
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
+H N++ L + E + ++++EL GG LF+ L + E+ L E E L+ + G
Sbjct: 72 QHPNVITLHEVYENKTD--VILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNG 126
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
+ +L + H DLKP NIM K+ DFG A ++ +F +++GT E++ P
Sbjct: 127 VYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAP 186
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ V +P+ G D+WSIGV Y + +G PF
Sbjct: 187 EI----VNYEPL----GLEADMWSIGVITYILLSGASPF 217
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 89.8 bits (213), Expect = 2e-17
Identities = 64/219 (29%), Positives = 107/219 (48%), Gaps = 20/219 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVK------TFNQLSHMRPHDVQMREFEVLKKV 65
+ T LG G V + K+ G A K T + + D++ RE +LK++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIE-REVSILKEI 71
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
+H N++ L + E + ++++EL GG LF+ L + E+ L E E L+ + G
Sbjct: 72 QHPNVITLHEVYENKTD--VILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNG 126
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
+ +L + H DLKP NIM K+ DFG A ++ +F +++GT E++ P
Sbjct: 127 VYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAP 186
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ V +P+ G D+WSIGV Y + +G PF
Sbjct: 187 EI----VNYEPL----GLEADMWSIGVITYILLSGASPF 217
>BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase 10
protein.
Length = 968
Score = 89.8 bits (213), Expect = 2e-17
Identities = 65/217 (29%), Positives = 103/217 (47%), Gaps = 15/217 (6%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
N VW LG GA G V++ NK G VA K S D + E E+L H
Sbjct: 33 NEVWEIVGELGDGAFGKVYKAKNKETGALVAAKVIETKSEEELED-YIVEIEILATCDHP 91
Query: 69 NIVKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
IVKLL GK+ I++E C GG++ I+ + + GL E + V + +
Sbjct: 92 YIVKLLGAYYHD---GKLWIMIEFCPGGAVDAIMLELDR--GLTEPQIQEVCRQMLEALN 146
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPD 186
L ++HRDLK GN++ + D +L DFG +A+ L+ ++ S GT ++ P+
Sbjct: 147 FLHSKRIIHRDLKAGNVLMTLEGD----IRLADFGVSAKNLKTLQKRDSFIGTPYWMAPE 202
Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ ++ + D+WS+G+TL +A + P
Sbjct: 203 VVMCETMK---DTPYDYKADIWSLGITLIEMAQIEPP 236
>BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein.
Length = 344
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/209 (34%), Positives = 98/209 (46%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
LGKGA V + + G+ A K N R H RE + + +KH NIV+L
Sbjct: 20 LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKSKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 189 D---PYGKPVDMWACGVILYILLVGYPPF 214
>BC019070-1|AAH19070.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II beta protein.
Length = 503
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + +KH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 89.8 bits (213), Expect = 2e-17
Identities = 69/224 (30%), Positives = 106/224 (47%), Gaps = 21/224 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ----LSHMRPHDVQMR---EFE 60
+ Y+ S T LG GA G V + + VA+K ++ + R D + E E
Sbjct: 218 DEYIMSKT--LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 275
Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
+LKK+ H I+K+ + ++ IV+EL GG LF D L+E L
Sbjct: 276 ILKKLNHPCIIKIKNFFDAED---YYIVLELMEGGELF---DKVVGNKRLKEATCKLYFY 329
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +++L +N ++HRDLKP N++ E+ K+TDFG ++ L E +L GT
Sbjct: 330 QMLLAVQYLHENGIIHRDLKPENVLLSSQEE-DCLIKITDFGHSKILGETSLMRTLCGTP 388
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
YL P+ VL + VD WS+GV L+ +G PF
Sbjct: 389 TYLAPE-----VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF 427
>AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 89.8 bits (213), Expect = 2e-17
Identities = 69/224 (30%), Positives = 106/224 (47%), Gaps = 21/224 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ----LSHMRPHDVQMR---EFE 60
+ Y+ S T LG GA G V + + VA+K ++ + R D + E E
Sbjct: 218 DEYIMSKT--LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 275
Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
+LKK+ H I+K+ + ++ IV+EL GG LF D L+E L
Sbjct: 276 ILKKLNHPCIIKIKNFFDAED---YYIVLELMEGGELF---DKVVGNKRLKEATCKLYFY 329
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +++L +N ++HRDLKP N++ E+ K+TDFG ++ L E +L GT
Sbjct: 330 QMLLAVQYLHENGIIHRDLKPENVLLSSQEE-DCLIKITDFGHSKILGETSLMRTLCGTP 388
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
YL P+ VL + VD WS+GV L+ +G PF
Sbjct: 389 TYLAPE-----VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF 427
>AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2
transcript variant del2-3 protein.
Length = 452
Score = 89.8 bits (213), Expect = 2e-17
Identities = 69/224 (30%), Positives = 106/224 (47%), Gaps = 21/224 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ----LSHMRPHDVQMR---EFE 60
+ Y+ S T LG GA G V + + VA+K ++ + R D + E E
Sbjct: 127 DEYIMSKT--LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 184
Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
+LKK+ H I+K+ + ++ IV+EL GG LF D L+E L
Sbjct: 185 ILKKLNHPCIIKIKNFFDAED---YYIVLELMEGGELF---DKVVGNKRLKEATCKLYFY 238
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +++L +N ++HRDLKP N++ E+ K+TDFG ++ L E +L GT
Sbjct: 239 QMLLAVQYLHENGIIHRDLKPENVLLSSQEE-DCLIKITDFGHSKILGETSLMRTLCGTP 297
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
YL P+ VL + VD WS+GV L+ +G PF
Sbjct: 298 TYLAPE-----VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF 336
>AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2
transcript variant insX protein.
Length = 586
Score = 89.8 bits (213), Expect = 2e-17
Identities = 69/224 (30%), Positives = 106/224 (47%), Gaps = 21/224 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ----LSHMRPHDVQMR---EFE 60
+ Y+ S T LG GA G V + + VA+K ++ + R D + E E
Sbjct: 261 DEYIMSKT--LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 318
Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
+LKK+ H I+K+ + ++ IV+EL GG LF D L+E L
Sbjct: 319 ILKKLNHPCIIKIKNFFDAED---YYIVLELMEGGELF---DKVVGNKRLKEATCKLYFY 372
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +++L +N ++HRDLKP N++ E+ K+TDFG ++ L E +L GT
Sbjct: 373 QMLLAVQYLHENGIIHRDLKPENVLLSSQEE-DCLIKITDFGHSKILGETSLMRTLCGTP 431
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
YL P+ VL + VD WS+GV L+ +G PF
Sbjct: 432 TYLAPE-----VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF 470
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 89.8 bits (213), Expect = 2e-17
Identities = 64/219 (29%), Positives = 107/219 (48%), Gaps = 20/219 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVK------TFNQLSHMRPHDVQMREFEVLKKV 65
+ T LG G V + K+ G A K T + + D++ RE +LK++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIE-REVSILKEI 71
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
+H N++ L + E + ++++EL GG LF+ L + E+ L E E L+ + G
Sbjct: 72 QHPNVITLHEVYENKTD--VILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNG 126
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
+ +L + H DLKP NIM K+ DFG A ++ +F +++GT E++ P
Sbjct: 127 VYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAP 186
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ V +P+ G D+WSIGV Y + +G PF
Sbjct: 187 EI----VNYEPL----GLEADMWSIGVITYILLSGASPF 217
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 89.8 bits (213), Expect = 2e-17
Identities = 64/219 (29%), Positives = 107/219 (48%), Gaps = 20/219 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVK------TFNQLSHMRPHDVQMREFEVLKKV 65
+ T LG G V + K+ G A K T + + D++ RE +LK++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIE-REVSILKEI 71
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
+H N++ L + E + ++++EL GG LF+ L + E+ L E E L+ + G
Sbjct: 72 QHPNVITLHEVYENKTD--VILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNG 126
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
+ +L + H DLKP NIM K+ DFG A ++ +F +++GT E++ P
Sbjct: 127 VYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAP 186
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ V +P+ G D+WSIGV Y + +G PF
Sbjct: 187 EI----VNYEPL----GLEADMWSIGVITYILLSGASPF 217
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 89.8 bits (213), Expect = 2e-17
Identities = 64/219 (29%), Positives = 107/219 (48%), Gaps = 20/219 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVK------TFNQLSHMRPHDVQMREFEVLKKV 65
+ T LG G V + K+ G A K T + + D++ RE +LK++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIE-REVSILKEI 71
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
+H N++ L + E + ++++EL GG LF+ L + E+ L E E L+ + G
Sbjct: 72 QHPNVITLHEVYENKTD--VILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNG 126
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
+ +L + H DLKP NIM K+ DFG A ++ +F +++GT E++ P
Sbjct: 127 VYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAP 186
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ V +P+ G D+WSIGV Y + +G PF
Sbjct: 187 EI----VNYEPL----GLEADMWSIGVITYILLSGASPF 217
>AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 89.8 bits (213), Expect = 2e-17
Identities = 69/224 (30%), Positives = 106/224 (47%), Gaps = 21/224 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ----LSHMRPHDVQMR---EFE 60
+ Y+ S T LG GA G V + + VA+K ++ + R D + E E
Sbjct: 218 DEYIMSKT--LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 275
Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
+LKK+ H I+K+ + ++ IV+EL GG LF D L+E L
Sbjct: 276 ILKKLNHPCIIKIKNFFDAED---YYIVLELMEGGELF---DKVVGNKRLKEATCKLYFY 329
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +++L +N ++HRDLKP N++ E+ K+TDFG ++ L E +L GT
Sbjct: 330 QMLLAVQYLHENGIIHRDLKPENVLLSSQEE-DCLIKITDFGHSKILGETSLMRTLCGTP 388
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
YL P+ VL + VD WS+GV L+ +G PF
Sbjct: 389 TYLAPE-----VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF 427
>AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 89.8 bits (213), Expect = 2e-17
Identities = 69/224 (30%), Positives = 106/224 (47%), Gaps = 21/224 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ----LSHMRPHDVQMR---EFE 60
+ Y+ S T LG GA G V + + VA+K ++ + R D + E E
Sbjct: 218 DEYIMSKT--LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 275
Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
+LKK+ H I+K+ + ++ IV+EL GG LF D L+E L
Sbjct: 276 ILKKLNHPCIIKIKNFFDAED---YYIVLELMEGGELF---DKVVGNKRLKEATCKLYFY 329
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +++L +N ++HRDLKP N++ E+ K+TDFG ++ L E +L GT
Sbjct: 330 QMLLAVQYLHENGIIHRDLKPENVLLSSQEE-DCLIKITDFGHSKILGETSLMRTLCGTP 388
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
YL P+ VL + VD WS+GV L+ +G PF
Sbjct: 389 TYLAPE-----VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF 427
>AK222703-1|BAD96423.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase IIB isoform
2 variant protein.
Length = 542
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + +KH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 4 protein.
Length = 518
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + +KH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 2 protein.
Length = 479
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + +KH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 1 protein.
Length = 503
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + +KH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein.
Length = 543
Score = 89.8 bits (213), Expect = 2e-17
Identities = 69/224 (30%), Positives = 106/224 (47%), Gaps = 21/224 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ----LSHMRPHDVQMR---EFE 60
+ Y+ S T LG GA G V + + VA+K ++ + R D + E E
Sbjct: 218 DEYIMSKT--LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 275
Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
+LKK+ H I+K+ + ++ IV+EL GG LF D L+E L
Sbjct: 276 ILKKLNHPCIIKIKNFFDAED---YYIVLELMEGGELF---DKVVGNKRLKEATCKLYFY 329
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +++L +N ++HRDLKP N++ E+ K+TDFG ++ L E +L GT
Sbjct: 330 QMLLAVQYLHENGIIHRDLKPENVLLSSQEE-DCLIKITDFGHSKILGETSLMRTLCGTP 388
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
YL P+ VL + VD WS+GV L+ +G PF
Sbjct: 389 TYLAPE-----VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF 427
>AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2
protein.
Length = 543
Score = 89.8 bits (213), Expect = 2e-17
Identities = 69/224 (30%), Positives = 106/224 (47%), Gaps = 21/224 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ----LSHMRPHDVQMR---EFE 60
+ Y+ S T LG GA G V + + VA+K ++ + R D + E E
Sbjct: 218 DEYIMSKT--LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 275
Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
+LKK+ H I+K+ + ++ IV+EL GG LF D L+E L
Sbjct: 276 ILKKLNHPCIIKIKNFFDAED---YYIVLELMEGGELF---DKVVGNKRLKEATCKLYFY 329
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +++L +N ++HRDLKP N++ E+ K+TDFG ++ L E +L GT
Sbjct: 330 QMLLAVQYLHENGIIHRDLKPENVLLSSQEE-DCLIKITDFGHSKILGETSLMRTLCGTP 388
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
YL P+ VL + VD WS+GV L+ +G PF
Sbjct: 389 TYLAPE-----VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF 427
>AF140350-1|AAD42070.1| 449|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 7
subunit protein.
Length = 449
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + +KH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein.
Length = 543
Score = 89.8 bits (213), Expect = 2e-17
Identities = 69/224 (30%), Positives = 106/224 (47%), Gaps = 21/224 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ----LSHMRPHDVQMR---EFE 60
+ Y+ S T LG GA G V + + VA+K ++ + R D + E E
Sbjct: 218 DEYIMSKT--LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 275
Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
+LKK+ H I+K+ + ++ IV+EL GG LF D L+E L
Sbjct: 276 ILKKLNHPCIIKIKNFFDAED---YYIVLELMEGGELF---DKVVGNKRLKEATCKLYFY 329
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +++L +N ++HRDLKP N++ E+ K+TDFG ++ L E +L GT
Sbjct: 330 QMLLAVQYLHENGIIHRDLKPENVLLSSQEE-DCLIKITDFGHSKILGETSLMRTLCGTP 388
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
YL P+ VL + VD WS+GV L+ +G PF
Sbjct: 389 TYLAPE-----VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF 427
>AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2
protein.
Length = 543
Score = 89.8 bits (213), Expect = 2e-17
Identities = 69/224 (30%), Positives = 106/224 (47%), Gaps = 21/224 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ----LSHMRPHDVQMR---EFE 60
+ Y+ S T LG GA G V + + VA+K ++ + R D + E E
Sbjct: 218 DEYIMSKT--LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 275
Query: 61 VLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLE 120
+LKK+ H I+K+ + ++ IV+EL GG LF D L+E L
Sbjct: 276 ILKKLNHPCIIKIKNFFDAED---YYIVLELMEGGELF---DKVVGNKRLKEATCKLYFY 329
Query: 121 HLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTE 180
+ +++L +N ++HRDLKP N++ E+ K+TDFG ++ L E +L GT
Sbjct: 330 QMLLAVQYLHENGIIHRDLKPENVLLSSQEE-DCLIKITDFGHSKILGETSLMRTLCGTP 388
Query: 181 EYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
YL P+ VL + VD WS+GV L+ +G PF
Sbjct: 389 TYLAPE-----VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF 427
>AF083419-1|AAD42038.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e
subunit protein.
Length = 517
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + +KH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>AF081924-1|AAD42037.1| 492|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 6
subunit protein.
Length = 492
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + +KH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>AF081572-1|AAD42036.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e'
subunit protein.
Length = 503
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + +KH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>AF078803-1|AAD42035.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/209 (34%), Positives = 99/209 (47%), Gaps = 16/209 (7%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAI 76
+GKGA V + V G A K N R H RE + + +KH NIV+L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
E EG +V +L TGG LF D Y E + ++ + + H +VH
Sbjct: 80 ISE-EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIQQILEAVLHCHQMGVVH 134
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRK 195
RDLKP N++ G KL DFG A E+Q ++Q + GT YL P+ VLRK
Sbjct: 135 RDLKPENLLLASKCKGAAV-KLADFGLAIEVQGDQQAWFGFAGTPGYLSPE-----VLRK 188
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+++G VD+W+ GV LY + G PF
Sbjct: 189 ---EAYGKPVDIWACGVILYILLVGYPPF 214
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 89.8 bits (213), Expect = 2e-17
Identities = 64/219 (29%), Positives = 107/219 (48%), Gaps = 20/219 (9%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVK------TFNQLSHMRPHDVQMREFEVLKKV 65
+ T LG G V + K+ G A K T + + D++ RE +LK++
Sbjct: 16 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIE-REVSILKEI 74
Query: 66 KHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAG 125
+H N++ L + E + ++++EL GG LF+ L + E+ L E E L+ + G
Sbjct: 75 QHPNVITLHEVYENKTD--VILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNG 129
Query: 126 MKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHP 185
+ +L + H DLKP NIM K+ DFG A ++ +F +++GT E++ P
Sbjct: 130 VYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAP 189
Query: 186 DMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
++ V +P+ G D+WSIGV Y + +G PF
Sbjct: 190 EI----VNYEPL----GLEADMWSIGVITYILLSGASPF 220
>AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein.
Length = 968
Score = 89.8 bits (213), Expect = 2e-17
Identities = 64/217 (29%), Positives = 103/217 (47%), Gaps = 15/217 (6%)
Query: 9 NYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHE 68
N VW LG GA G V++ NK G A K S D + E E+L H
Sbjct: 33 NEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIV-EIEILATCDHP 91
Query: 69 NIVKLLAIEEEQEGRGKV-IVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMK 127
IVKLL GK+ I++E C GG++ I+ + + GL E + +V + +
Sbjct: 92 YIVKLLGAYYHD---GKLWIMIEFCPGGAVDAIMLELDR--GLTEPQIQVVCRQMLEALN 146
Query: 128 HLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPD 186
L ++HRDLK GN++ + D +L DFG +A+ L+ ++ S GT ++ P+
Sbjct: 147 FLHSKRIIHRDLKAGNVLMTLEGD----IRLADFGVSAKNLKTLQKRDSFIGTPYWMAPE 202
Query: 187 MYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ ++ + D+WS+G+TL +A + P
Sbjct: 203 VVMCETMK---DTPYDYKADIWSLGITLIEMAQIEPP 236
>X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase
protein.
Length = 387
Score = 89.4 bits (212), Expect = 3e-17
Identities = 69/226 (30%), Positives = 110/226 (48%), Gaps = 22/226 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLS--HMRPHDVQ------MREF 59
ENY +LG+G + V + ++K + AVK + P +V+ ++E
Sbjct: 18 ENY--EPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 60 EVLKKVK-HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLV 118
++L+KV H NI++L + + +V +L G LF+ L + L E E +
Sbjct: 76 DILRKVSGHPNIIQLK--DTYETNTFFFLVFDLMKRGELFDYLTEKVT---LSEKETRKI 130
Query: 119 LEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYG 178
+ L + L N+VHRDLKP NI+ D KLTDFG + +L+ E+ + G
Sbjct: 131 MRALLEVICTLHKLNIVHRDLKPENILL----DDNMNIKLTDFGFSCQLEPGERLREVCG 186
Query: 179 TEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
T YL P++ E ++ G +G VD+WS GV +Y + G PF
Sbjct: 187 TPSYLAPEIIECSMNEDHPG--YGKEVDMWSTGVIMYTLLAGSPPF 230
>D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein.
Length = 1351
Score = 89.4 bits (212), Expect = 3e-17
Identities = 75/230 (32%), Positives = 117/230 (50%), Gaps = 23/230 (10%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ---LSHMRPHDVQMR----E 58
G + +ST S LG GA G V+ V+K + V VK + L D ++ E
Sbjct: 1014 GEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLE 1073
Query: 59 FEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILD-DPENTYGLQEYEFLL 117
+L +V+H NI+K+L I E Q G ++++ + +G LF +D P L Y F
Sbjct: 1074 IAILSRVEHANIIKVLDIFENQ-GFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 1132
Query: 118 VL---EHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFV 174
V L + + +LR +++HRD+K NI+ I ED T KL DFG+A L+ + F
Sbjct: 1133 VRAGQSRLVSAVGYLRLKDIIHRDIKDENIV--IAED--FTIKLIDFGSAAYLERGKLFY 1188
Query: 175 SLYGTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ GT EY P++ ++ P G +++WS+GVTLY + + PF
Sbjct: 1189 TFCGTIEYCAPEV----LMGNPYR---GPELEMWSLGVTLYTLVFEENPF 1231
>BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 89.4 bits (212), Expect = 3e-17
Identities = 69/226 (30%), Positives = 110/226 (48%), Gaps = 22/226 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLS--HMRPHDVQ------MREF 59
ENY +LG+G + V + ++K + AVK + P +V+ ++E
Sbjct: 18 ENY--EPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 60 EVLKKVK-HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLV 118
++L+KV H NI++L + + +V +L G LF+ L + L E E +
Sbjct: 76 DILRKVSGHPNIIQLK--DTYETNTFFFLVFDLMKRGELFDYLTEKVT---LSEKETRKI 130
Query: 119 LEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYG 178
+ L + L N+VHRDLKP NI+ D KLTDFG + +L+ E+ + G
Sbjct: 131 MRALLEVICTLHKLNIVHRDLKPENILL----DDNMNIKLTDFGFSCQLEPGERLREVCG 186
Query: 179 TEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
T YL P++ E ++ G +G VD+WS GV +Y + G PF
Sbjct: 187 TPSYLAPEIIECSMNEDHPG--YGKEVDMWSTGVIMYTLLAGSPPF 230
>BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 89.4 bits (212), Expect = 3e-17
Identities = 69/226 (30%), Positives = 110/226 (48%), Gaps = 22/226 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLS--HMRPHDVQ------MREF 59
ENY +LG+G + V + ++K + AVK + P +V+ ++E
Sbjct: 18 ENY--EPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 60 EVLKKVK-HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLV 118
++L+KV H NI++L + + +V +L G LF+ L + L E E +
Sbjct: 76 DILRKVSGHPNIIQLK--DTYETNTFFFLVFDLMKRGELFDYLTEKVT---LSEKETRKI 130
Query: 119 LEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYG 178
+ L + L N+VHRDLKP NI+ D KLTDFG + +L+ E+ + G
Sbjct: 131 MRALLEVICTLHKLNIVHRDLKPENILL----DDNMNIKLTDFGFSCQLEPGERLREVCG 186
Query: 179 TEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
T YL P++ E ++ G +G VD+WS GV +Y + G PF
Sbjct: 187 TPSYLAPEIIECSMNEDHPG--YGKEVDMWSTGVIMYTLLAGSPPF 230
>BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 89.4 bits (212), Expect = 3e-17
Identities = 69/226 (30%), Positives = 110/226 (48%), Gaps = 22/226 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLS--HMRPHDVQ------MREF 59
ENY +LG+G + V + ++K + AVK + P +V+ ++E
Sbjct: 18 ENY--EPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 60 EVLKKVK-HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLV 118
++L+KV H NI++L + + +V +L G LF+ L + L E E +
Sbjct: 76 DILRKVSGHPNIIQLK--DTYETNTFFFLVFDLMKRGELFDYLTEKVT---LSEKETRKI 130
Query: 119 LEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYG 178
+ L + L N+VHRDLKP NI+ D KLTDFG + +L+ E+ + G
Sbjct: 131 MRALLEVICTLHKLNIVHRDLKPENILL----DDNMNIKLTDFGFSCQLEPGERLREVCG 186
Query: 179 TEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
T YL P++ E ++ G +G VD+WS GV +Y + G PF
Sbjct: 187 TPSYLAPEIIECSMNEDHPG--YGKEVDMWSTGVIMYTLLAGSPPF 230
>BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 89.4 bits (212), Expect = 3e-17
Identities = 69/226 (30%), Positives = 110/226 (48%), Gaps = 22/226 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLS--HMRPHDVQ------MREF 59
ENY +LG+G + V + ++K + AVK + P +V+ ++E
Sbjct: 18 ENY--EPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 60 EVLKKVK-HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLV 118
++L+KV H NI++L + + +V +L G LF+ L + L E E +
Sbjct: 76 DILRKVSGHPNIIQLK--DTYETNTFFFLVFDLMKRGELFDYLTEKVT---LSEKETRKI 130
Query: 119 LEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYG 178
+ L + L N+VHRDLKP NI+ D KLTDFG + +L+ E+ + G
Sbjct: 131 MRALLEVICTLHKLNIVHRDLKPENILL----DDNMNIKLTDFGFSCQLEPGERLREVCG 186
Query: 179 TEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
T YL P++ E ++ G +G VD+WS GV +Y + G PF
Sbjct: 187 TPSYLAPEIIECSMNEDHPG--YGKEVDMWSTGVIMYTLLAGSPPF 230
>BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing
serine/threonine kinase protein.
Length = 1323
Score = 89.4 bits (212), Expect = 3e-17
Identities = 74/227 (32%), Positives = 116/227 (51%), Gaps = 24/227 (10%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ---LSHMRPHDVQMR----E 58
G + +ST S LG GA G V+ V+K + V VK + L D ++ E
Sbjct: 993 GEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLE 1052
Query: 59 FEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILD-DPENTYGLQEYEFLL 117
+L +V+H NI+K+L I E Q G ++++ + +G LF +D P L Y F
Sbjct: 1053 IAILSRVEHANIIKVLDIFENQ-GFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIF-- 1109
Query: 118 VLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY 177
L + + +LR +++HRD+K NI+ I ED T KL DFG+A L+ + F +
Sbjct: 1110 --RQLVSAVGYLRLKDIIHRDIKDENIV--IAED--FTIKLIDFGSAAYLERGKLFYTFC 1163
Query: 178 GTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
GT EY P++ ++ P G +++WS+GVTLY + + PF
Sbjct: 1164 GTIEYCAPEV----LMGNPYR---GPELEMWSLGVTLYTLVFEENPF 1203
>BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 89.4 bits (212), Expect = 3e-17
Identities = 69/226 (30%), Positives = 110/226 (48%), Gaps = 22/226 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLS--HMRPHDVQ------MREF 59
ENY +LG+G + V + ++K + AVK + P +V+ ++E
Sbjct: 18 ENY--EPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 60 EVLKKVK-HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLV 118
++L+KV H NI++L + + +V +L G LF+ L + L E E +
Sbjct: 76 DILRKVSGHPNIIQLK--DTYETNTFFFLVFDLMKRGELFDYLTEKVT---LSEKETRKI 130
Query: 119 LEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYG 178
+ L + L N+VHRDLKP NI+ D KLTDFG + +L+ E+ + G
Sbjct: 131 MRALLEVICTLHKLNIVHRDLKPENILL----DDNMNIKLTDFGFSCQLEPGERLREVCG 186
Query: 179 TEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
T YL P++ E ++ G +G VD+WS GV +Y + G PF
Sbjct: 187 TPSYLAPEIIECSMNEDHPG--YGKEVDMWSTGVIMYTLLAGSPPF 230
>BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein.
Length = 953
Score = 89.4 bits (212), Expect = 3e-17
Identities = 74/227 (32%), Positives = 116/227 (51%), Gaps = 24/227 (10%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ---LSHMRPHDVQMR----E 58
G + +ST S LG GA G V+ V+K + V VK + L D ++ E
Sbjct: 623 GEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLE 682
Query: 59 FEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILD-DPENTYGLQEYEFLL 117
+L +V+H NI+K+L I E Q G ++++ + +G LF +D P L Y F
Sbjct: 683 IAILSRVEHANIIKVLDIFENQ-GFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIF-- 739
Query: 118 VLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY 177
L + + +LR +++HRD+K NI+ I ED T KL DFG+A L+ + F +
Sbjct: 740 --RQLVSAVGYLRLKDIIHRDIKDENIV--IAED--FTIKLIDFGSAAYLERGKLFYTFC 793
Query: 178 GTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
GT EY P++ ++ P G +++WS+GVTLY + + PF
Sbjct: 794 GTIEYCAPEV----LMGNPYR---GPELEMWSLGVTLYTLVFEENPF 833
>AL732423-2|CAM17479.1| 748|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 748
Score = 89.4 bits (212), Expect = 3e-17
Identities = 65/214 (30%), Positives = 108/214 (50%), Gaps = 17/214 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G + +N +A+K + + E + K +KH NIV+ L
Sbjct: 92 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKYLKHRNIVQYLGS 150
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNLV 135
E G K+ ME GGSL +L + +G ++E + + G+K+L +N +V
Sbjct: 151 VSEN-GYIKIF-MEQVPGGSLSALL---RSKWGPMKEPTIKFYTKQILEGLKYLHENQIV 205
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLR 194
HRD+K N++ +N K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 206 HRDIKGDNVL--VNTYSGVV-KISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQG--- 259
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +GA D+WS+G T+ +AT + PF G
Sbjct: 260 -PRG--YGAPADIWSLGCTIIEMATSKPPFHELG 290
>AL732423-1|CAM17478.1| 788|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 788
Score = 89.4 bits (212), Expect = 3e-17
Identities = 65/214 (30%), Positives = 108/214 (50%), Gaps = 17/214 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G + +N +A+K + + E + K +KH NIV+ L
Sbjct: 132 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKYLKHRNIVQYLGS 190
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNLV 135
E G K+ ME GGSL +L + +G ++E + + G+K+L +N +V
Sbjct: 191 VSEN-GYIKIF-MEQVPGGSLSALL---RSKWGPMKEPTIKFYTKQILEGLKYLHENQIV 245
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLR 194
HRD+K N++ +N K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 246 HRDIKGDNVL--VNTYSGVV-KISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQG--- 299
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +GA D+WS+G T+ +AT + PF G
Sbjct: 300 -PRG--YGAPADIWSLGCTIIEMATSKPPFHELG 330
>AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 788
Score = 89.4 bits (212), Expect = 3e-17
Identities = 65/214 (30%), Positives = 108/214 (50%), Gaps = 17/214 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G + +N +A+K + + E + K +KH NIV+ L
Sbjct: 132 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKYLKHRNIVQYLGS 190
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNLV 135
E G K+ ME GGSL +L + +G ++E + + G+K+L +N +V
Sbjct: 191 VSEN-GYIKIF-MEQVPGGSLSALL---RSKWGPMKEPTIKFYTKQILEGLKYLHENQIV 245
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLR 194
HRD+K N++ +N K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 246 HRDIKGDNVL--VNTYSGVV-KISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQG--- 299
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +GA D+WS+G T+ +AT + PF G
Sbjct: 300 -PRG--YGAPADIWSLGCTIIEMATSKPPFHELG 330
>AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 748
Score = 89.4 bits (212), Expect = 3e-17
Identities = 65/214 (30%), Positives = 108/214 (50%), Gaps = 17/214 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G + +N +A+K + + E + K +KH NIV+ L
Sbjct: 92 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKYLKHRNIVQYLGS 150
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNLV 135
E G K+ ME GGSL +L + +G ++E + + G+K+L +N +V
Sbjct: 151 VSEN-GYIKIF-MEQVPGGSLSALL---RSKWGPMKEPTIKFYTKQILEGLKYLHENQIV 205
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLR 194
HRD+K N++ +N K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 206 HRDIKGDNVL--VNTYSGVV-KISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQG--- 259
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +GA D+WS+G T+ +AT + PF G
Sbjct: 260 -PRG--YGAPADIWSLGCTIIEMATSKPPFHELG 290
>AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens
cDNA FLJ16518 fis, clone NT2RI3007443, moderately
similar to MITOGEN-ACTIVATED PROTEIN KINASE KINASE
KINASE 5 (EC ).
Length = 748
Score = 89.4 bits (212), Expect = 3e-17
Identities = 65/214 (30%), Positives = 108/214 (50%), Gaps = 17/214 (7%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G + +N +A+K + + E + K +KH NIV+ L
Sbjct: 92 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH-EEIALHKYLKHRNIVQYLGS 150
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNLV 135
E G K+ ME GGSL +L + +G ++E + + G+K+L +N +V
Sbjct: 151 VSEN-GYIKIF-MEQVPGGSLSALL---RSKWGPMKEPTIKFYTKQILEGLKYLHENQIV 205
Query: 136 HRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLR 194
HRD+K N++ +N K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 206 HRDIKGDNVL--VNTYSGVV-KISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQG--- 259
Query: 195 KPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +GA D+WS+G T+ +AT + PF G
Sbjct: 260 -PRG--YGAPADIWSLGCTIIEMATSKPPFHELG 290
>AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein.
Length = 1323
Score = 89.4 bits (212), Expect = 3e-17
Identities = 74/227 (32%), Positives = 116/227 (51%), Gaps = 24/227 (10%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ---LSHMRPHDVQMR----E 58
G + +ST S LG GA G V+ V+K + V VK + L D ++ E
Sbjct: 993 GEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLE 1052
Query: 59 FEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILD-DPENTYGLQEYEFLL 117
+L +V+H NI+K+L I E Q G ++++ + +G LF +D P L Y F
Sbjct: 1053 IAILSRVEHANIIKVLDIFENQ-GFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIF-- 1109
Query: 118 VLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY 177
L + + +LR +++HRD+K NI+ I ED T KL DFG+A L+ + F +
Sbjct: 1110 --RQLVSAVGYLRLKDIIHRDIKDENIV--IAED--FTIKLIDFGSAAYLERGKLFYTFC 1163
Query: 178 GTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
GT EY P++ ++ P G +++WS+GVTLY + + PF
Sbjct: 1164 GTIEYCAPEV----LMGNPYR---GPELEMWSLGVTLYTLVFEENPF 1203
>AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase gamma
protein.
Length = 387
Score = 89.4 bits (212), Expect = 3e-17
Identities = 69/226 (30%), Positives = 110/226 (48%), Gaps = 22/226 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLS--HMRPHDVQ------MREF 59
ENY +LG+G + V + ++K + AVK + P +V+ ++E
Sbjct: 18 ENY--EPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 60 EVLKKVK-HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLV 118
++L+KV H NI++L + + +V +L G LF+ L + L E E +
Sbjct: 76 DILRKVSGHPNIIQLK--DTYETNTFFFLVFDLMKRGELFDYLTEKVT---LSEKETRKI 130
Query: 119 LEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYG 178
+ L + L N+VHRDLKP NI+ D KLTDFG + +L+ E+ + G
Sbjct: 131 MRALLEVICTLHKLNIVHRDLKPENILL----DDNMNIKLTDFGFSCQLEPGERLREVCG 186
Query: 179 TEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
T YL P++ E ++ G +G VD+WS GV +Y + G PF
Sbjct: 187 TPSYLAPEIIECSMNEDHPG--YGKEVDMWSTGVIMYTLLAGSPPF 230
>AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein.
Length = 387
Score = 89.4 bits (212), Expect = 3e-17
Identities = 69/226 (30%), Positives = 110/226 (48%), Gaps = 22/226 (9%)
Query: 8 ENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLS--HMRPHDVQ------MREF 59
ENY +LG+G + V + ++K + AVK + P +V+ ++E
Sbjct: 18 ENY--EPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 60 EVLKKVK-HENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLV 118
++L+KV H NI++L + + +V +L G LF+ L + L E E +
Sbjct: 76 DILRKVSGHPNIIQLK--DTYETNTFFFLVFDLMKRGELFDYLTEKVT---LSEKETRKI 130
Query: 119 LEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYG 178
+ L + L N+VHRDLKP NI+ D KLTDFG + +L+ E+ + G
Sbjct: 131 MRALLEVICTLHKLNIVHRDLKPENILL----DDNMNIKLTDFGFSCQLEPGERLREVCG 186
Query: 179 TEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
T YL P++ E ++ G +G VD+WS GV +Y + G PF
Sbjct: 187 TPSYLAPEIIECSMNEDHPG--YGKEVDMWSTGVIMYTLLAGSPPF 230
>AF415197-1|AAM33514.1| 566|Homo sapiens
calcium/calmodulin-dependent protein kinase II gamma
protein.
Length = 566
Score = 89.0 bits (211), Expect = 4e-17
Identities = 71/206 (34%), Positives = 98/206 (47%), Gaps = 16/206 (7%)
Query: 21 GATGAVFQGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVKLLAIEEE 79
GA V + V K + + A K N R H RE + + +KH NIV+L E
Sbjct: 1 GAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISE 60
Query: 80 QEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHRDL 139
EG +V +L TGG LF D Y E + + + + H+ +++VHRDL
Sbjct: 61 -EGF-HYLVFDLVTGGELFE--DIVAREY-YSEADASHCIHQILESVNHIHQHDIVHRDL 115
Query: 140 KPGNIMKYINEDGTTTYKLTDFGAARELQEEEQ-FVSLYGTEEYLHPDMYERAVLRKPVG 198
KP N++ G KL DFG A E+Q E+Q + GT YL P+ VLRK
Sbjct: 116 KPENLLLASKCKGAAV-KLADFGLAIEVQGEQQAWFGFAGTPGYLSPE-----VLRK--- 166
Query: 199 KSFGATVDLWSIGVTLYHVATGQLPF 224
+G VD+W+ GV LY + G PF
Sbjct: 167 DPYGKPVDIWACGVILYILLVGYPPF 192
>Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamma
subunit protein.
Length = 406
Score = 88.6 bits (210), Expect = 5e-17
Identities = 68/216 (31%), Positives = 108/216 (50%), Gaps = 19/216 (8%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVK----TFNQLSHMRPHDVQ---MREFEVLKKVK-HE 68
V+G+G + V + V++ G AVK T +LS + +V+ RE +L++V H
Sbjct: 29 VIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHP 88
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
+I+ L I+ + +V +L G LF+ L + L E E ++ L +
Sbjct: 89 HIITL--IDSYESSSFMFLVFDLMRKGELFDYLTEK---VALSEKETRSIMRSLLEAVSF 143
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMY 188
L NN+VHRDLKP NI+ D +L+DFG + L+ E+ L GT YL P++
Sbjct: 144 LHANNIVHRDLKPENILL----DDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEIL 199
Query: 189 ERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ ++ G +G VDLW+ GV L+ + G PF
Sbjct: 200 KCSMDETHPG--YGKEVDLWACGVILFTLLAGSPPF 233
>U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein
kinase protein.
Length = 458
Score = 88.6 bits (210), Expect = 5e-17
Identities = 74/227 (32%), Positives = 115/227 (50%), Gaps = 24/227 (10%)
Query: 6 GSENYVWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQ---LSHMRPHDVQMR----E 58
G + +ST S LG GA G V+ V+K + V VK + L D ++ E
Sbjct: 128 GEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLE 187
Query: 59 FEVLKKVKHENIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILD-DPENTYGLQEYEFLL 117
+L +V+H NI+K+L I E Q G ++++ + +G LF +D P L Y F
Sbjct: 188 IAILSRVEHANIIKVLDIFENQ-GFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIF-- 244
Query: 118 VLEHLTAGMKHLRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY 177
L + + +LR +++HRD K NI+ I ED T KL DFG+A L+ + F +
Sbjct: 245 --RQLVSAVGYLRLKDIIHRDFKDENIV--IAED--FTIKLIDFGSAAYLERGKLFYTFC 298
Query: 178 GTEEYLHPDMYERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
GT EY P++ ++ P G +++WS+GVTLY + + PF
Sbjct: 299 GTIEYCAPEV----LMGNPYR---GPELEMWSLGVTLYTLVFEENPF 338
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 88.6 bits (210), Expect = 5e-17
Identities = 75/233 (32%), Positives = 118/233 (50%), Gaps = 27/233 (11%)
Query: 17 VLGKGATGAVFQGVNKNNGEPV----AVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIV 71
VLG+G+ G VF V K +G A+K + + +R E ++L +V H IV
Sbjct: 73 VLGQGSFGKVFL-VKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIV 131
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KL + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 132 KL-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHS 186
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYER 190
+++RDLKP NI+ ++E+G KLTDFG ++E + E++ S GT EY+ P++ R
Sbjct: 187 LGIIYRDLKPENIL--LDEEGHI--KLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNR 242
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 243 --------RGHTQSADWWSFGVLMFEMLTGTLPFQ---GKDRKETMTMILKAK 284
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/263 (26%), Positives = 123/263 (46%), Gaps = 23/263 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + ++K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI----LLRYGQHPNIITLKDVY 483
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
++ G+ +V EL GG L LD E E VL +T +++L +VHR
Sbjct: 484 DD--GKYVYVVTELMKGGEL---LDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHR 538
Query: 138 DLKPGNIMKYINEDGT-TTYKLTDFGAARELQEEE-QFVSLYGTEEYLHPDMYERAVLRK 195
DLKP NI+ Y++E G + ++ DFG A++L+ E ++ T ++ P++ +R
Sbjct: 539 DLKPSNIL-YVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR----- 592
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKAS---GVISGTQ 252
+ + A D+WS+GV LY + TG PF +E + I + K S G +
Sbjct: 593 ---QGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVS 649
Query: 253 TTENGPIDWARELPPHCQLSVGL 275
T + + PH +L+ L
Sbjct: 650 DTAKDLVSKMLHVDPHQRLTAAL 672
>M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase
protein.
Length = 406
Score = 88.6 bits (210), Expect = 5e-17
Identities = 68/216 (31%), Positives = 108/216 (50%), Gaps = 19/216 (8%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVK----TFNQLSHMRPHDVQ---MREFEVLKKVK-HE 68
V+G+G + V + V++ G AVK T +LS + +V+ RE +L++V H
Sbjct: 29 VIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHP 88
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
+I+ L I+ + +V +L G LF+ L + L E E ++ L +
Sbjct: 89 HIITL--IDSYESSSFMFLVFDLMRKGELFDYLTEK---VALSEKETRSIMRSLLEAVSF 143
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMY 188
L NN+VHRDLKP NI+ D +L+DFG + L+ E+ L GT YL P++
Sbjct: 144 LHANNIVHRDLKPENILL----DDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEIL 199
Query: 189 ERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ ++ G +G VDLW+ GV L+ + G PF
Sbjct: 200 KCSMDETHPG--YGKEVDLWACGVILFTLLAGSPPF 233
>L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kinase
3 protein.
Length = 580
Score = 88.6 bits (210), Expect = 5e-17
Identities = 75/233 (32%), Positives = 118/233 (50%), Gaps = 27/233 (11%)
Query: 17 VLGKGATGAVFQGVNKNNGEPV----AVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIV 71
VLG+G+ G VF V K +G A+K + + +R E ++L +V H IV
Sbjct: 72 VLGQGSFGKVFL-VKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIV 130
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KL + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 131 KL-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHS 185
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYER 190
+++RDLKP NI+ ++E+G KLTDFG ++E + E++ S GT EY+ P++ R
Sbjct: 186 LGIIYRDLKPENIL--LDEEGHI--KLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNR 241
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 242 --------RGHTQSADWWSFGVLMFEMLTGTLPFQ---GKDRKETMTMILKAK 283
Score = 54.0 bits (124), Expect = 1e-06
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 14/155 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + ++K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 427 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI----LLRYGQHPNIITLNDVY 482
Query: 78 EEQEGRGK-VIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
++ GK V V+ L GG L LD E E VL +T +++L +VH
Sbjct: 483 DD----GKYVYVVTLMKGGEL---LDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVH 535
Query: 137 RDLKPGNIMKYINEDGT-TTYKLTDFGAARELQEE 170
RDLKP NI+ Y++E G + ++ DFG A++L+ E
Sbjct: 536 RDLKPSNIL-YVDESGNPESIRICDFGFAKQLRAE 569
>D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein.
Length = 1164
Score = 88.6 bits (210), Expect = 5e-17
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 13/213 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG GA G V++ NK A K + S D M E ++L H NIV
Sbjct: 46 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDY-MVEIDILASCDHPNIV 104
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KLL + I++E C GG++ ++ + E L E + +V + + +L D
Sbjct: 105 KLLDAFYYENNLW--ILIEFCAGGAVDAVMLELERP--LTESQIQVVCKQTLDALNYLHD 160
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYER 190
N ++HRDLK GNI+ ++ D KL DFG +A+ + ++ S GT ++ P++
Sbjct: 161 NKIIHRDLKAGNILFTLDGD----IKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEV--- 213
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + + D+WS+G+TL +A + P
Sbjct: 214 VMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 246
>BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 88.6 bits (210), Expect = 5e-17
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G +++ +A+K + + E + ++++H+NIV+ L
Sbjct: 219 VLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLH-EEIALHRRLRHKNIVRYLG- 276
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+G I ME GGSL ++L E + G+ +L DN++VH
Sbjct: 277 -SASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVH 335
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 336 RDIKGDNVL--INTF-SGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQG---- 388
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 389 PRG--YGKAADIWSLGCTVIEMATGRPPFHELG 419
>BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 88.6 bits (210), Expect = 5e-17
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G +++ +A+K + + E + ++++H+NIV+ L
Sbjct: 219 VLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLH-EEIALHRRLRHKNIVRYLG- 276
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+G I ME GGSL ++L E + G+ +L DN++VH
Sbjct: 277 -SASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVH 335
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 336 RDIKGDNVL--INTF-SGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQG---- 388
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 389 PRG--YGKAADIWSLGCTVIEMATGRPPFHELG 419
>BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein.
Length = 1204
Score = 88.6 bits (210), Expect = 5e-17
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 13/213 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG GA G V++ NK A K + S D M E ++L H NIV
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDY-MVEIDILASCDHPNIV 92
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KLL + I++E C GG++ ++ + E L E + +V + + +L D
Sbjct: 93 KLLDAFYYENNLW--ILIEFCAGGAVDAVMLELERP--LTESQIQVVCKQTLDALNYLHD 148
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYER 190
N ++HRDLK GNI+ ++ D KL DFG +A+ + ++ S GT ++ P++
Sbjct: 149 NKIIHRDLKAGNILFTLDGD----IKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEV--- 201
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + + D+WS+G+TL +A + P
Sbjct: 202 VMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
>BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein.
Length = 441
Score = 88.6 bits (210), Expect = 5e-17
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G +++ +A+K + + E + ++++H+NIV+ L
Sbjct: 122 VLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLH-EEIALHRRLRHKNIVRYLG- 179
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+G I ME GGSL ++L E + G+ +L DN++VH
Sbjct: 180 -SASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVH 238
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 239 RDIKGDNVL--INTF-SGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQG---- 291
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 292 PRG--YGKAADIWSLGCTVIEMATGRPPFHELG 322
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 88.6 bits (210), Expect = 5e-17
Identities = 75/233 (32%), Positives = 118/233 (50%), Gaps = 27/233 (11%)
Query: 17 VLGKGATGAVFQGVNKNNGEPV----AVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIV 71
VLG+G+ G VF V K +G A+K + + +R E ++L +V H IV
Sbjct: 73 VLGQGSFGKVFL-VKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIV 131
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KL + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 132 KL-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHS 186
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYER 190
+++RDLKP NI+ ++E+G KLTDFG ++E + E++ S GT EY+ P++ R
Sbjct: 187 LGIIYRDLKPENIL--LDEEGHI--KLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNR 242
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 243 --------RGHTQSADWWSFGVLMFEMLTGTLPFQ---GKDRKETMTMILKAK 284
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/263 (26%), Positives = 123/263 (46%), Gaps = 23/263 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + ++K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI----LLRYGQHPNIITLKDVY 483
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
++ G+ +V EL GG L LD E E VL +T +++L +VHR
Sbjct: 484 DD--GKYVYVVTELMKGGEL---LDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHR 538
Query: 138 DLKPGNIMKYINEDGT-TTYKLTDFGAARELQEEE-QFVSLYGTEEYLHPDMYERAVLRK 195
DLKP NI+ Y++E G + ++ DFG A++L+ E ++ T ++ P++ +R
Sbjct: 539 DLKPSNIL-YVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR----- 592
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKAS---GVISGTQ 252
+ + A D+WS+GV LY + TG PF +E + I + K S G +
Sbjct: 593 ---QGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVS 649
Query: 253 TTENGPIDWARELPPHCQLSVGL 275
T + + PH +L+ L
Sbjct: 650 DTAKDLVSKMLHVDPHQRLTAAL 672
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 88.6 bits (210), Expect = 5e-17
Identities = 75/233 (32%), Positives = 118/233 (50%), Gaps = 27/233 (11%)
Query: 17 VLGKGATGAVFQGVNKNNGEPV----AVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIV 71
VLG+G+ G VF V K +G A+K + + +R E ++L +V H IV
Sbjct: 73 VLGQGSFGKVFL-VKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIV 131
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KL + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 132 KL-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHS 186
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYER 190
+++RDLKP NI+ ++E+G KLTDFG ++E + E++ S GT EY+ P++ R
Sbjct: 187 LGIIYRDLKPENIL--LDEEGHI--KLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNR 242
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 243 --------RGHTQSADWWSFGVLMFEMLTGTLPFQ---GKDRKETMTMILKAK 284
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/263 (26%), Positives = 123/263 (46%), Gaps = 23/263 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + ++K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI----LLRYGQHPNIITLKDVY 483
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
++ G+ +V EL GG L LD E E VL +T +++L +VHR
Sbjct: 484 DD--GKYVYVVTELMKGGEL---LDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHR 538
Query: 138 DLKPGNIMKYINEDGT-TTYKLTDFGAARELQEEE-QFVSLYGTEEYLHPDMYERAVLRK 195
DLKP NI+ Y++E G + ++ DFG A++L+ E ++ T ++ P++ +R
Sbjct: 539 DLKPSNIL-YVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR----- 592
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKAS---GVISGTQ 252
+ + A D+WS+GV LY + TG PF +E + I + K S G +
Sbjct: 593 ---QGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVS 649
Query: 253 TTENGPIDWARELPPHCQLSVGL 275
T + + PH +L+ L
Sbjct: 650 DTAKDLVSKMLHVDPHQRLTAAL 672
>BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein.
Length = 617
Score = 88.6 bits (210), Expect = 5e-17
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 13/213 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG GA G V++ NK A K + S D M E ++L H NIV
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDY-MVEIDILASCDHPNIV 92
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KLL + I++E C GG++ ++ + E L E + +V + + +L D
Sbjct: 93 KLLDAFYYENNLW--ILIEFCAGGAVDAVMLELERP--LTESQIQVVCKQTLDALNYLHD 148
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYER 190
N ++HRDLK GNI+ ++ D KL DFG +A+ + ++ S GT ++ P++
Sbjct: 149 NKIIHRDLKAGNILFTLDGD----IKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEV--- 201
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + + D+WS+G+TL +A + P
Sbjct: 202 VMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
>BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein.
Length = 426
Score = 88.6 bits (210), Expect = 5e-17
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 13/213 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG GA G V++ NK A K + S D M E ++L H NIV
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDY-MVEIDILASCDHPNIV 92
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KLL + I++E C GG++ ++ + E L E + +V + + +L D
Sbjct: 93 KLLDAFYYENNLW--ILIEFCAGGAVDAVMLELERP--LTESQIQVVCKQTLDALNYLHD 148
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYER 190
N ++HRDLK GNI+ ++ D KL DFG +A+ + ++ S GT ++ P++
Sbjct: 149 NKIIHRDLKAGNILFTLDGD----IKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEV--- 201
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + + D+WS+G+TL +A + P
Sbjct: 202 VMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
>BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein.
Length = 614
Score = 88.6 bits (210), Expect = 5e-17
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 13/213 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG GA G V++ NK A K + S D M E ++L H NIV
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDY-MVEIDILASCDHPNIV 92
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KLL + I++E C GG++ ++ + E L E + +V + + +L D
Sbjct: 93 KLLDAFYYENNLW--ILIEFCAGGAVDAVMLELERP--LTESQIQVVCKQTLDALNYLHD 148
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYER 190
N ++HRDLK GNI+ ++ D KL DFG +A+ + ++ S GT ++ P++
Sbjct: 149 NKIIHRDLKAGNILFTLDGD----IKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEV--- 201
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + + D+WS+G+TL +A + P
Sbjct: 202 VMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
>BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein.
Length = 797
Score = 88.6 bits (210), Expect = 5e-17
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G +++ +A+K + + E + ++++H+NIV+ L
Sbjct: 376 VLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLH-EEIALHRRLRHKNIVRYLG- 433
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+G I ME GGSL ++L E + G+ +L DN++VH
Sbjct: 434 -SASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVH 492
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 493 RDIKGDNVL--INTF-SGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQG---- 545
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 546 PRG--YGKAADIWSLGCTVIEMATGRPPFHELG 576
>BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase,
gamma 2 (testis) protein.
Length = 406
Score = 88.6 bits (210), Expect = 5e-17
Identities = 68/216 (31%), Positives = 108/216 (50%), Gaps = 19/216 (8%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVK----TFNQLSHMRPHDVQ---MREFEVLKKVK-HE 68
V+G+G + V + V++ G AVK T +LS + +V+ RE +L++V H
Sbjct: 29 VIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHP 88
Query: 69 NIVKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKH 128
+I+ L I+ + +V +L G LF+ L + L E E ++ L +
Sbjct: 89 HIITL--IDSYESSSFMFLVFDLMRKGELFDYLTEK---VALSEKETRSIMRSLLEAVSF 143
Query: 129 LRDNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMY 188
L NN+VHRDLKP NI+ D +L+DFG + L+ E+ L GT YL P++
Sbjct: 144 LHANNIVHRDLKPENILL----DDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEIL 199
Query: 189 ERAVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ ++ G +G VDLW+ GV L+ + G PF
Sbjct: 200 KCSMDETHPG--YGKEVDLWACGVILFTLLAGSPPF 233
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 88.6 bits (210), Expect = 5e-17
Identities = 75/233 (32%), Positives = 118/233 (50%), Gaps = 27/233 (11%)
Query: 17 VLGKGATGAVFQGVNKNNGEPV----AVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIV 71
VLG+G+ G VF V K +G A+K + + +R E ++L +V H IV
Sbjct: 73 VLGQGSFGKVFL-VKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIV 131
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KL + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 132 KL-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHS 186
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYER 190
+++RDLKP NI+ ++E+G KLTDFG ++E + E++ S GT EY+ P++ R
Sbjct: 187 LGIIYRDLKPENIL--LDEEGHI--KLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNR 242
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 243 --------RGHTQSADWWSFGVLMFEMLTGTLPFQ---GKDRKETMTMILKAK 284
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/263 (26%), Positives = 123/263 (46%), Gaps = 23/263 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + ++K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI----LLRYGQHPNIITLKDVY 483
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
++ G+ +V EL GG L LD E E VL +T +++L +VHR
Sbjct: 484 DD--GKYVYVVTELMKGGEL---LDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHR 538
Query: 138 DLKPGNIMKYINEDGT-TTYKLTDFGAARELQEEE-QFVSLYGTEEYLHPDMYERAVLRK 195
DLKP NI+ Y++E G + ++ DFG A++L+ E ++ T ++ P++ +R
Sbjct: 539 DLKPSNIL-YVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR----- 592
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKAS---GVISGTQ 252
+ + A D+WS+GV LY + TG PF +E + I + K S G +
Sbjct: 593 ---QGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVS 649
Query: 253 TTENGPIDWARELPPHCQLSVGL 275
T + + PH +L+ L
Sbjct: 650 DTAKDLVSKMLHVDPHQRLTAAL 672
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 88.6 bits (210), Expect = 5e-17
Identities = 75/233 (32%), Positives = 118/233 (50%), Gaps = 27/233 (11%)
Query: 17 VLGKGATGAVFQGVNKNNGEPV----AVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIV 71
VLG+G+ G VF V K +G A+K + + +R E ++L +V H IV
Sbjct: 73 VLGQGSFGKVFL-VKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIV 131
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KL + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 132 KL-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHS 186
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYER 190
+++RDLKP NI+ ++E+G KLTDFG ++E + E++ S GT EY+ P++ R
Sbjct: 187 LGIIYRDLKPENIL--LDEEGHI--KLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNR 242
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 243 --------RGHTQSADWWSFGVLMFEMLTGTLPFQ---GKDRKETMTMILKAK 284
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/263 (26%), Positives = 123/263 (46%), Gaps = 23/263 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + ++K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI----LLRYGQHPNIITLKDVY 483
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
++ G+ +V EL GG L LD E E VL +T +++L +VHR
Sbjct: 484 DD--GKYVYVVTELMKGGEL---LDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHR 538
Query: 138 DLKPGNIMKYINEDGT-TTYKLTDFGAARELQEEE-QFVSLYGTEEYLHPDMYERAVLRK 195
DLKP NI+ Y++E G + ++ DFG A++L+ E ++ T ++ P++ +R
Sbjct: 539 DLKPSNIL-YVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR----- 592
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKAS---GVISGTQ 252
+ + A D+WS+GV LY + TG PF +E + I + K S G +
Sbjct: 593 ---QGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVS 649
Query: 253 TTENGPIDWARELPPHCQLSVGL 275
T + + PH +L+ L
Sbjct: 650 DTAKDLVSKMLHVDPHQRLTAAL 672
>AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 797
Score = 88.6 bits (210), Expect = 5e-17
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G +++ +A+K + + E + ++++H+NIV+ L
Sbjct: 376 VLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLH-EEIALHRRLRHKNIVRYLG- 433
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+G I ME GGSL ++L E + G+ +L DN++VH
Sbjct: 434 -SASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVH 492
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 493 RDIKGDNVL--INTF-SGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQG---- 545
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 546 PRG--YGKAADIWSLGCTVIEMATGRPPFHELG 576
>AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1288
Score = 88.6 bits (210), Expect = 5e-17
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G +++ +A+K + + E + ++++H+NIV+ L
Sbjct: 653 VLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLH-EEIALHRRLRHKNIVRYLG- 710
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+G I ME GGSL ++L E + G+ +L DN++VH
Sbjct: 711 -SASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVH 769
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 770 RDIKGDNVL--INTF-SGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQG---- 822
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 823 PRG--YGKAADIWSLGCTVIEMATGRPPFHELG 853
>AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 88.6 bits (210), Expect = 5e-17
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 13/213 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG GA G V++ NK A K + S D M E ++L H NIV
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDY-MVEIDILASCDHPNIV 92
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KLL + I++E C GG++ ++ + E L E + +V + + +L D
Sbjct: 93 KLLDAFYYENNLW--ILIEFCAGGAVDAVMLELERP--LTESQIQVVCKQTLDALNYLHD 148
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYER 190
N ++HRDLK GNI+ ++ D KL DFG +A+ + ++ S GT ++ P++
Sbjct: 149 NKIIHRDLKAGNILFTLDGD----IKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEV--- 201
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + + D+WS+G+TL +A + P
Sbjct: 202 VMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
>AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 88.6 bits (210), Expect = 5e-17
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 13/213 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG GA G V++ NK A K + S D M E ++L H NIV
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDY-MVEIDILASCDHPNIV 92
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KLL + I++E C GG++ ++ + E L E + +V + + +L D
Sbjct: 93 KLLDAFYYENNLW--ILIEFCAGGAVDAVMLELERP--LTESQIQVVCKQTLDALNYLHD 148
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYER 190
N ++HRDLK GNI+ ++ D KL DFG +A+ + ++ S GT ++ P++
Sbjct: 149 NKIIHRDLKAGNILFTLDGD----IKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEV--- 201
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + + D+WS+G+TL +A + P
Sbjct: 202 VMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
>AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 88.6 bits (210), Expect = 5e-17
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 13/213 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG GA G V++ NK A K + S D M E ++L H NIV
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDY-MVEIDILASCDHPNIV 92
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KLL + I++E C GG++ ++ + E L E + +V + + +L D
Sbjct: 93 KLLDAFYYENNLW--ILIEFCAGGAVDAVMLELERP--LTESQIQVVCKQTLDALNYLHD 148
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYER 190
N ++HRDLK GNI+ ++ D KL DFG +A+ + ++ S GT ++ P++
Sbjct: 149 NKIIHRDLKAGNILFTLDGD----IKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEV--- 201
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + + D+WS+G+TL +A + P
Sbjct: 202 VMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
>AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 88.6 bits (210), Expect = 5e-17
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 13/213 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG GA G V++ NK A K + S D M E ++L H NIV
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDY-MVEIDILASCDHPNIV 92
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KLL + I++E C GG++ ++ + E L E + +V + + +L D
Sbjct: 93 KLLDAFYYENNLW--ILIEFCAGGAVDAVMLELERP--LTESQIQVVCKQTLDALNYLHD 148
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYER 190
N ++HRDLK GNI+ ++ D KL DFG +A+ + ++ S GT ++ P++
Sbjct: 149 NKIIHRDLKAGNILFTLDGD----IKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEV--- 201
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + + D+WS+G+TL +A + P
Sbjct: 202 VMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
>AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20-9
protein.
Length = 1235
Score = 88.6 bits (210), Expect = 5e-17
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 13/213 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG GA G V++ NK A K + S D M E ++L H NIV
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDY-MVEIDILASCDHPNIV 92
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KLL + I++E C GG++ ++ + E L E + +V + + +L D
Sbjct: 93 KLLDAFYYENNLW--ILIEFCAGGAVDAVMLELERP--LTESQIQVVCKQTLDALNYLHD 148
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYER 190
N ++HRDLK GNI+ ++ D KL DFG +A+ + ++ S GT ++ P++
Sbjct: 149 NKIIHRDLKAGNILFTLDGD----IKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEV--- 201
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + + D+WS+G+TL +A + P
Sbjct: 202 VMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
>AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1011
Score = 88.6 bits (210), Expect = 5e-17
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G +++ +A+K + + E + ++++H+NIV+ L
Sbjct: 376 VLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLH-EEIALHRRLRHKNIVRYLG- 433
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+G I ME GGSL ++L E + G+ +L DN++VH
Sbjct: 434 -SASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVH 492
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 493 RDIKGDNVL--INTF-SGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQG---- 545
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 546 PRG--YGKAADIWSLGCTVIEMATGRPPFHELG 576
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 variant protein.
Length = 806
Score = 88.6 bits (210), Expect = 5e-17
Identities = 75/233 (32%), Positives = 118/233 (50%), Gaps = 27/233 (11%)
Query: 17 VLGKGATGAVFQGVNKNNGEPV----AVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIV 71
VLG+G+ G VF V K +G A+K + + +R E ++L +V H IV
Sbjct: 140 VLGQGSFGKVFL-VKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIV 198
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KL + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 199 KL-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHS 253
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYER 190
+++RDLKP NI+ ++E+G KLTDFG ++E + E++ S GT EY+ P++ R
Sbjct: 254 LGIIYRDLKPENIL--LDEEGHI--KLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNR 309
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 310 --------RGHTQSADWWSFGVLMFEMLTGTLPFQ---GKDRKETMTMILKAK 351
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/263 (26%), Positives = 123/263 (46%), Gaps = 23/263 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + ++K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 494 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI----LLRYGQHPNIITLKDVY 549
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
++ G+ +V EL GG L LD E E VL +T +++L +VHR
Sbjct: 550 DD--GKYVYVVTELMKGGEL---LDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHR 604
Query: 138 DLKPGNIMKYINEDGT-TTYKLTDFGAARELQEEE-QFVSLYGTEEYLHPDMYERAVLRK 195
DLKP NI+ Y++E G + ++ DFG A++L+ E ++ T ++ P++ +R
Sbjct: 605 DLKPSNIL-YVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR----- 658
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKAS---GVISGTQ 252
+ + A D+WS+GV LY + TG PF +E + I + K S G +
Sbjct: 659 ---QGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVS 715
Query: 253 TTENGPIDWARELPPHCQLSVGL 275
T + + PH +L+ L
Sbjct: 716 DTAKDLVSKMLHVDPHQRLTAAL 738
>AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 variant protein.
Length = 1192
Score = 88.6 bits (210), Expect = 5e-17
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G +++ +A+K + + E + ++++H+NIV+ L
Sbjct: 557 VLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLH-EEIALHRRLRHKNIVRYLG- 614
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+G I ME GGSL ++L E + G+ +L DN++VH
Sbjct: 615 -SASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVH 673
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 674 RDIKGDNVL--INTF-SGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQG---- 726
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 727 PRG--YGKAADIWSLGCTVIEMATGRPPFHELG 757
>AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis
signal-regulating kinase 2 protein.
Length = 1288
Score = 88.6 bits (210), Expect = 5e-17
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 13/213 (6%)
Query: 17 VLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAI 76
VLGKG G V+ G +++ +A+K + + E + ++++H+NIV+ L
Sbjct: 653 VLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLH-EEIALHRRLRHKNIVRYLG- 710
Query: 77 EEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVH 136
+G I ME GGSL ++L E + G+ +L DN++VH
Sbjct: 711 -SASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVH 769
Query: 137 RDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLY-GTEEYLHPDMYERAVLRK 195
RD+K N++ IN + K++DFG ++ L + GT +Y+ P++ ++
Sbjct: 770 RDIKGDNVL--INTF-SGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQG---- 822
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYG 228
P G +G D+WS+G T+ +ATG+ PF G
Sbjct: 823 PRG--YGKAADIWSLGCTVIEMATGRPPFHELG 853
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 88.6 bits (210), Expect = 5e-17
Identities = 75/233 (32%), Positives = 118/233 (50%), Gaps = 27/233 (11%)
Query: 17 VLGKGATGAVFQGVNKNNGEPV----AVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIV 71
VLG+G+ G VF V K +G A+K + + +R E ++L +V H IV
Sbjct: 59 VLGQGSFGKVFL-VKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIV 117
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KL + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 118 KL-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHS 172
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYER 190
+++RDLKP NI+ ++E+G KLTDFG ++E + E++ S GT EY+ P++ R
Sbjct: 173 LGIIYRDLKPENIL--LDEEGHI--KLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNR 228
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 229 --------RGHTQSADWWSFGVLMFEMLTGTLPFQ---GKDRKETMTMILKAK 270
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/263 (26%), Positives = 123/263 (46%), Gaps = 23/263 (8%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + ++K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 414 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI----LLRYGQHPNIITLKDVY 469
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
++ G+ +V EL GG L LD E E VL +T +++L +VHR
Sbjct: 470 DD--GKYVYVVTELMKGGEL---LDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHR 524
Query: 138 DLKPGNIMKYINEDGT-TTYKLTDFGAARELQEEE-QFVSLYGTEEYLHPDMYERAVLRK 195
DLKP NI+ Y++E G + ++ DFG A++L+ E ++ T ++ P++ +R
Sbjct: 525 DLKPSNIL-YVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR----- 578
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKKAS---GVISGTQ 252
+ + A D+WS+GV LY + TG PF +E + I + K S G +
Sbjct: 579 ---QGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVS 635
Query: 253 TTENGPIDWARELPPHCQLSVGL 275
T + + PH +L+ L
Sbjct: 636 DTAKDLVSKMLHVDPHQRLTAAL 658
>AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein.
Length = 1204
Score = 88.6 bits (210), Expect = 5e-17
Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 13/213 (6%)
Query: 12 WSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIV 71
W LG GA G V++ NK A K + S D M E ++L H NIV
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDY-MVEIDILASCDHPNIV 92
Query: 72 KLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRD 131
KLL + I++E C GG++ ++ + E L E + +V + + +L D
Sbjct: 93 KLLDAFYYENNLW--ILIEFCAGGAVDAVMLELERP--LTESQIQVVCKQTLDALNYLHD 148
Query: 132 NNLVHRDLKPGNIMKYINEDGTTTYKLTDFG-AARELQEEEQFVSLYGTEEYLHPDMYER 190
N ++HRDLK GNI+ ++ D KL DFG +A+ + ++ S GT ++ P++
Sbjct: 149 NKIIHRDLKAGNILFTLDGD----IKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEV--- 201
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLP 223
+ + + D+WS+G+TL +A + P
Sbjct: 202 VMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 88.2 bits (209), Expect = 6e-17
Identities = 71/232 (30%), Positives = 118/232 (50%), Gaps = 25/232 (10%)
Query: 17 VLGKGATGAVF---QGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVK 72
VLG+G+ G VF + + G+ A+K + + +R E ++L +V H IVK
Sbjct: 64 VLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVK 123
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
L + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 124 L-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHSL 178
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYERA 191
+++RDLKP NI+ ++E+G K+TDFG ++E + +++ S GT EY+ P++ R
Sbjct: 179 GIIYRDLKPENIL--LDEEGHI--KITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNR- 233
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 234 -------RGHTQSADWWSFGVLMFEMLTGSLPFQ---GKDRKETMALILKAK 275
Score = 71.3 bits (167), Expect = 8e-12
Identities = 59/209 (28%), Positives = 103/209 (49%), Gaps = 20/209 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + V+K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 421 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI----LLRYGQHPNIITLKDVY 476
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
++ G+ +VMEL GG L LD E E VL +T M +L +VHR
Sbjct: 477 DD--GKFVYLVMELMRGGEL---LDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHR 531
Query: 138 DLKPGNIMKYINEDGT-TTYKLTDFGAARELQE-EEQFVSLYGTEEYLHPDMYERAVLRK 195
DLKP NI+ Y +E G+ + ++ DFG A++L+ ++ T ++ P++ +R
Sbjct: 532 DLKPSNIL-YRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKR----- 585
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + A D+WS+G+ LY + G PF
Sbjct: 586 ---QGYDAACDIWSLGILLYTMLAGFTPF 611
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 88.2 bits (209), Expect = 6e-17
Identities = 71/232 (30%), Positives = 118/232 (50%), Gaps = 25/232 (10%)
Query: 17 VLGKGATGAVF---QGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVK 72
VLG+G+ G VF + + G+ A+K + + +R E ++L +V H IVK
Sbjct: 64 VLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVK 123
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
L + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 124 L-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHSL 178
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYERA 191
+++RDLKP NI+ ++E+G K+TDFG ++E + +++ S GT EY+ P++ R
Sbjct: 179 GIIYRDLKPENIL--LDEEGHI--KITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNR- 233
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 234 -------RGHTQSADWWSFGVLMFEMLTGSLPFQ---GKDRKETMALILKAK 275
Score = 71.3 bits (167), Expect = 8e-12
Identities = 59/209 (28%), Positives = 103/209 (49%), Gaps = 20/209 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + V+K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 421 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI----LLRYGQHPNIITLKDVY 476
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
++ G+ +VMEL GG L LD E E VL +T M +L +VHR
Sbjct: 477 DD--GKFVYLVMELMRGGEL---LDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHR 531
Query: 138 DLKPGNIMKYINEDGT-TTYKLTDFGAARELQE-EEQFVSLYGTEEYLHPDMYERAVLRK 195
DLKP NI+ Y +E G+ + ++ DFG A++L+ ++ T ++ P++ +R
Sbjct: 532 DLKPSNIL-YRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKR----- 585
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + A D+WS+G+ LY + G PF
Sbjct: 586 ---QGYDAACDIWSLGILLYTMLAGFTPF 611
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 88.2 bits (209), Expect = 6e-17
Identities = 63/211 (29%), Positives = 105/211 (49%), Gaps = 23/211 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKLLA 75
+GKG V + G VAVK ++ + + P +Q RE ++K + H NIVKL
Sbjct: 66 IGKGNFAKVKLARHVLTGREVAVKIIDK-TQLNPTSLQKLFREVRIMKILNHPNIVKLFE 124
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E + + +VME +GG +F+ L +G ++E E + + +++ +
Sbjct: 125 VIETE--KTLYLVMEYASGGEVFDYLV----AHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
VHRDLK N++ DG K+ DFG + E + + G+ Y P++++
Sbjct: 179 VHRDLKAENLLL----DGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQ----- 229
Query: 195 KPVGKSF-GATVDLWSIGVTLYHVATGQLPF 224
GK + G VD+WS+GV LY + +G LPF
Sbjct: 230 ---GKKYDGPEVDVWSLGVILYTLVSGSLPF 257
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 88.2 bits (209), Expect = 6e-17
Identities = 63/211 (29%), Positives = 105/211 (49%), Gaps = 23/211 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKLLA 75
+GKG V + G VAVK ++ + + P +Q RE ++K + H NIVKL
Sbjct: 66 IGKGNFAKVKLARHVLTGREVAVKIIDK-TQLNPTSLQKLFREVRIMKILNHPNIVKLFE 124
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E + + +VME +GG +F+ L +G ++E E + + +++ +
Sbjct: 125 VIETE--KTLYLVMEYASGGEVFDYLV----AHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
VHRDLK N++ DG K+ DFG + E + + G+ Y P++++
Sbjct: 179 VHRDLKAENLLL----DGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQ----- 229
Query: 195 KPVGKSF-GATVDLWSIGVTLYHVATGQLPF 224
GK + G VD+WS+GV LY + +G LPF
Sbjct: 230 ---GKKYDGPEVDVWSLGVILYTLVSGSLPF 257
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 88.2 bits (209), Expect = 6e-17
Identities = 71/232 (30%), Positives = 118/232 (50%), Gaps = 25/232 (10%)
Query: 17 VLGKGATGAVF---QGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVK 72
VLG+G+ G VF + + G+ A+K + + +R E ++L +V H IVK
Sbjct: 64 VLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVK 123
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
L + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 124 L-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHSL 178
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYERA 191
+++RDLKP NI+ ++E+G K+TDFG ++E + +++ S GT EY+ P++ R
Sbjct: 179 GIIYRDLKPENIL--LDEEGHI--KITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNR- 233
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 234 -------RGHTQSADWWSFGVLMFEMLTGSLPFQ---GKDRKETMALILKAK 275
Score = 71.3 bits (167), Expect = 8e-12
Identities = 59/209 (28%), Positives = 103/209 (49%), Gaps = 20/209 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + V+K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 421 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI----LLRYGQHPNIITLKDVY 476
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
++ G+ +VMEL GG L LD E E VL +T M +L +VHR
Sbjct: 477 DD--GKFVYLVMELMRGGEL---LDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHR 531
Query: 138 DLKPGNIMKYINEDGT-TTYKLTDFGAARELQE-EEQFVSLYGTEEYLHPDMYERAVLRK 195
DLKP NI+ Y +E G+ + ++ DFG A++L+ ++ T ++ P++ +R
Sbjct: 532 DLKPSNIL-YRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKR----- 585
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + A D+WS+G+ LY + G PF
Sbjct: 586 ---QGYDAACDIWSLGILLYTMLAGFTPF 611
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 88.2 bits (209), Expect = 6e-17
Identities = 63/211 (29%), Positives = 105/211 (49%), Gaps = 23/211 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKLLA 75
+GKG V + G VAVK ++ + + P +Q RE ++K + H NIVKL
Sbjct: 66 IGKGNFAKVKLARHVLTGREVAVKIIDK-TQLNPTSLQKLFREVRIMKILNHPNIVKLFE 124
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E + + +VME +GG +F+ L +G ++E E + + +++ +
Sbjct: 125 VIETE--KTLYLVMEYASGGEVFDYLV----AHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
VHRDLK N++ DG K+ DFG + E + + G+ Y P++++
Sbjct: 179 VHRDLKAENLLL----DGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQ----- 229
Query: 195 KPVGKSF-GATVDLWSIGVTLYHVATGQLPF 224
GK + G VD+WS+GV LY + +G LPF
Sbjct: 230 ---GKKYDGPEVDVWSLGVILYTLVSGSLPF 257
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 88.2 bits (209), Expect = 6e-17
Identities = 71/232 (30%), Positives = 118/232 (50%), Gaps = 25/232 (10%)
Query: 17 VLGKGATGAVF---QGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVK 72
VLG+G+ G VF + + G+ A+K + + +R E ++L +V H IVK
Sbjct: 64 VLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVK 123
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
L + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 124 L-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHSL 178
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYERA 191
+++RDLKP NI+ ++E+G K+TDFG ++E + +++ S GT EY+ P++ R
Sbjct: 179 GIIYRDLKPENIL--LDEEGHI--KITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNR- 233
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 234 -------RGHTQSADWWSFGVLMFEMLTGSLPFQ---GKDRKETMALILKAK 275
Score = 71.3 bits (167), Expect = 8e-12
Identities = 59/209 (28%), Positives = 103/209 (49%), Gaps = 20/209 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + V+K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 421 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI----LLRYGQHPNIITLKDVY 476
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
++ G+ +VMEL GG L LD E E VL +T M +L +VHR
Sbjct: 477 DD--GKFVYLVMELMRGGEL---LDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHR 531
Query: 138 DLKPGNIMKYINEDGT-TTYKLTDFGAARELQE-EEQFVSLYGTEEYLHPDMYERAVLRK 195
DLKP NI+ Y +E G+ + ++ DFG A++L+ ++ T ++ P++ +R
Sbjct: 532 DLKPSNIL-YRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKR----- 585
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + A D+WS+G+ LY + G PF
Sbjct: 586 ---QGYDAACDIWSLGILLYTMLAGFTPF 611
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 88.2 bits (209), Expect = 6e-17
Identities = 63/211 (29%), Positives = 105/211 (49%), Gaps = 23/211 (10%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQ--MREFEVLKKVKHENIVKLLA 75
+GKG V + G VAVK ++ + + P +Q RE ++K + H NIVKL
Sbjct: 66 IGKGNFAKVKLARHVLTGREVAVKIIDK-TQLNPTSLQKLFREVRIMKILNHPNIVKLFE 124
Query: 76 IEEEQEGRGKVIVMELCTGGSLFNILDDPENTYG-LQEYEFLLVLEHLTAGMKHLRDNNL 134
+ E + + +VME +GG +F+ L +G ++E E + + +++ +
Sbjct: 125 VIETE--KTLYLVMEYASGGEVFDYLV----AHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
Query: 135 VHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYERAVLR 194
VHRDLK N++ DG K+ DFG + E + + G+ Y P++++
Sbjct: 179 VHRDLKAENLLL----DGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQ----- 229
Query: 195 KPVGKSF-GATVDLWSIGVTLYHVATGQLPF 224
GK + G VD+WS+GV LY + +G LPF
Sbjct: 230 ---GKKYDGPEVDVWSLGVILYTLVSGSLPF 257
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 88.2 bits (209), Expect = 6e-17
Identities = 71/232 (30%), Positives = 118/232 (50%), Gaps = 25/232 (10%)
Query: 17 VLGKGATGAVF---QGVNKNNGEPVAVKTFNQLS-HMRPHDVQMREFEVLKKVKHENIVK 72
VLG+G+ G VF + + G+ A+K + + +R E ++L +V H IVK
Sbjct: 137 VLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVK 196
Query: 73 LLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDN 132
L + EG+ ++++ GG LF L E + ++ +F L L + HL
Sbjct: 197 L-HYAFQTEGK-LYLILDFLRGGDLFTRLSK-EVMFTEEDVKFYLA--ELALALDHLHSL 251
Query: 133 NLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARE-LQEEEQFVSLYGTEEYLHPDMYERA 191
+++RDLKP NI+ ++E+G K+TDFG ++E + +++ S GT EY+ P++ R
Sbjct: 252 GIIYRDLKPENIL--LDEEGHI--KITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNR- 306
Query: 192 VLRKPVGKSFGATVDLWSIGVTLYHVATGQLPFRPYGGRRNKETMFYITTKK 243
+ + D WS GV ++ + TG LPF+ G+ KETM I K
Sbjct: 307 -------RGHTQSADWWSFGVLMFEMLTGSLPFQ---GKDRKETMALILKAK 348
Score = 71.3 bits (167), Expect = 8e-12
Identities = 59/209 (28%), Positives = 103/209 (49%), Gaps = 20/209 (9%)
Query: 18 LGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENIVKLLAIE 77
+G G+ + V+K AVK ++ ++++ +L+ +H NI+ L +
Sbjct: 494 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI----LLRYGQHPNIITLKDVY 549
Query: 78 EEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLRDNNLVHR 137
++ G+ +VMEL GG L LD E E VL +T M +L +VHR
Sbjct: 550 DD--GKFVYLVMELMRGGEL---LDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHR 604
Query: 138 DLKPGNIMKYINEDGT-TTYKLTDFGAARELQE-EEQFVSLYGTEEYLHPDMYERAVLRK 195
DLKP NI+ Y +E G+ + ++ DFG A++L+ ++ T ++ P++ +R
Sbjct: 605 DLKPSNIL-YRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKR----- 658
Query: 196 PVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ + A D+WS+G+ LY + G PF
Sbjct: 659 ---QGYDAACDIWSLGILLYTMLAGFTPF 684
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 87.8 bits (208), Expect = 9e-17
Identities = 67/214 (31%), Positives = 104/214 (48%), Gaps = 14/214 (6%)
Query: 11 VWSTTSVLGKGATGAVFQGVNKNNGEPVAVKTFNQLSHMRPHDVQMREFEVLKKVKHENI 70
++ VLG GA V +K + VA+K + + E VL K+KH NI
Sbjct: 19 IYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPNI 78
Query: 71 VKLLAIEEEQEGRGKVIVMELCTGGSLFNILDDPENTYGLQEYEFLLVLEHLTAGMKHLR 130
V L I E G ++M+L +GG LF+ + E + + L+ + L A +K+L
Sbjct: 79 VALDDIYES--GGHLYLIMQLVSGGELFDRI--VEKGFYTERDASRLIFQVLDA-VKYLH 133
Query: 131 DNNLVHRDLKPGNIMKYINEDGTTTYKLTDFGAARELQEEEQFVSLYGTEEYLHPDMYER 190
D +VHRDLKP N++ Y + D + ++DFG ++ + GT Y+ P++
Sbjct: 134 DLGIVHRDLKPENLL-YYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEV--- 189
Query: 191 AVLRKPVGKSFGATVDLWSIGVTLYHVATGQLPF 224
+ +KP K+ VD WSIGV Y + G PF
Sbjct: 190 -LAQKPYSKA----VDCWSIGVIAYILLCGYPPF 218
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.315 0.132 0.379
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 77,713,116
Number of Sequences: 224733
Number of extensions: 3282345
Number of successful extensions: 16760
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 804
Number of HSP's successfully gapped in prelim test: 1754
Number of HSP's that attempted gapping in prelim test: 11670
Number of HSP's gapped (non-prelim): 3105
length of query: 543
length of database: 73,234,838
effective HSP length: 94
effective length of query: 449
effective length of database: 52,109,936
effective search space: 23397361264
effective search space used: 23397361264
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 68 (31.5 bits)
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