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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000197-TA|BGIBMGA000197-PA|IPR003754|Uroporphyrinogen
III synthase HEM4
         (248 letters)

Database: fruitfly 
           52,641 sequences; 24,830,863 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AY060729-1|AAL28277.1|  277|Drosophila melanogaster GH17465p pro...   109   3e-24
AE014298-1242|AAF46419.1|  277|Drosophila melanogaster CG1885-PA...   109   3e-24
AE014297-2078|AAF55222.1|  253|Drosophila melanogaster CG9589-PA...    84   2e-16
BT001564-1|AAN71319.1|  578|Drosophila melanogaster RE16347p pro...    30   2.6  
BT001318-1|AAN71073.1|  633|Drosophila melanogaster AT15149p pro...    30   2.6  
AY061832-1|AAL27643.1|  564|Drosophila melanogaster SD06513p pro...    30   2.6  
AY058508-1|AAL13737.1|  522|Drosophila melanogaster LD21426p pro...    30   2.6  
AE014298-3078|AAF50863.1|  522|Drosophila melanogaster CG1753-PB...    30   2.6  
AE014298-3077|AAF50862.1|  522|Drosophila melanogaster CG1753-PA...    30   2.6  
AE014134-2584|ABC65906.1|  348|Drosophila melanogaster CG31732-P...    30   2.6  
AE014134-2583|AAN10894.1|  564|Drosophila melanogaster CG31732-P...    30   2.6  
AE014134-2582|AAF53447.2|  578|Drosophila melanogaster CG31732-P...    30   2.6  
AE014134-2579|ABC65903.1|  660|Drosophila melanogaster CG31732-P...    30   2.6  
AE014134-2578|AAF53449.4|  890|Drosophila melanogaster CG31732-P...    30   2.6  
AE014134-2581|ABC65905.1|  738|Drosophila melanogaster CG31732-P...    30   3.4  
AE014134-2580|ABC65904.1|  592|Drosophila melanogaster CG31732-P...    30   3.4  
AY071192-1|AAL48814.1|  689|Drosophila melanogaster RE24065p pro...    29   4.6  
AE014297-1097|AAF54497.1|  689|Drosophila melanogaster CG6217-PA...    29   4.6  
BT001640-1|AAN71395.1|  475|Drosophila melanogaster RE40923p pro...    29   6.0  
AE014296-2218|AAN11841.1|  475|Drosophila melanogaster CG32115-P...    29   6.0  

>AY060729-1|AAL28277.1|  277|Drosophila melanogaster GH17465p
           protein.
          Length = 277

 Score =  109 bits (263), Expect = 3e-24
 Identities = 79/247 (31%), Positives = 119/247 (48%), Gaps = 9/247 (3%)

Query: 3   IVLFKGESED---YQRIFRENNFETIFVEPLQFIYINIEELSQKLLQND-YDGMILTSPR 58
           +++FK ESE    Y     +++F  +FV  L F + N++EL  KL   D Y G+I TSPR
Sbjct: 8   VIIFKSESESSDVYAETLEKHDFNPVFVPTLSFGFKNLDELRAKLQNPDKYAGIIFTSPR 67

Query: 59  AVEAVSKCWDPTKFVI-WNSKDVYTVGEMSSQ-KIKXXXXXXXXXXXXXNAENLSKIILK 116
            VEAV++  +  +    W     Y VGE++    +              NA  L   I+ 
Sbjct: 68  CVEAVAESLNLGELPGGWKMLHNYAVGEVTHNLALSTLDQLFTHGKQTGNARALGDYIVD 127

Query: 117 --DKKKTSTFLFPCGNLRSETIPNMLQSEGITLDAITVYETQENENLKA-LLMELNNLND 173
             D  +    L PCGNL ++T+ + L   G ++DA  VYET+ +  L A +   L    +
Sbjct: 128 TFDGSRALPLLLPCGNLATDTLLSKLAENGFSVDACEVYETRCHPELGANVERALEIYGE 187

Query: 174 SPSGLAFFSPSGCEYIHRQLQTFSNRLSLLPHFAIGNSTAHKIENLGVEIAGVAAKPKAE 233
           S   LAFFSPSG     +   +    +      AIG ST   +E+LG ++   A +P  E
Sbjct: 188 SIEFLAFFSPSGVNCAQQYFTSRQLSMDKWKLVAIGPSTRRALESLGQKVYCTAERPTVE 247

Query: 234 SLVESVL 240
            LV+ +L
Sbjct: 248 HLVKVLL 254


>AE014298-1242|AAF46419.1|  277|Drosophila melanogaster CG1885-PA
           protein.
          Length = 277

 Score =  109 bits (263), Expect = 3e-24
 Identities = 79/247 (31%), Positives = 119/247 (48%), Gaps = 9/247 (3%)

Query: 3   IVLFKGESED---YQRIFRENNFETIFVEPLQFIYINIEELSQKLLQND-YDGMILTSPR 58
           +++FK ESE    Y     +++F  +FV  L F + N++EL  KL   D Y G+I TSPR
Sbjct: 8   VIIFKSESESSDVYAETLEKHDFNPVFVPTLSFGFKNLDELRAKLQNPDKYAGIIFTSPR 67

Query: 59  AVEAVSKCWDPTKFVI-WNSKDVYTVGEMSSQ-KIKXXXXXXXXXXXXXNAENLSKIILK 116
            VEAV++  +  +    W     Y VGE++    +              NA  L   I+ 
Sbjct: 68  CVEAVAESLNLGELPGGWKMLHNYAVGEVTHNLALSTLDQLFTHGKQTGNARALGDYIVD 127

Query: 117 --DKKKTSTFLFPCGNLRSETIPNMLQSEGITLDAITVYETQENENLKA-LLMELNNLND 173
             D  +    L PCGNL ++T+ + L   G ++DA  VYET+ +  L A +   L    +
Sbjct: 128 TFDGSRALPLLLPCGNLATDTLLSKLAENGFSVDACEVYETRCHPELGANVERALEIYGE 187

Query: 174 SPSGLAFFSPSGCEYIHRQLQTFSNRLSLLPHFAIGNSTAHKIENLGVEIAGVAAKPKAE 233
           S   LAFFSPSG     +   +    +      AIG ST   +E+LG ++   A +P  E
Sbjct: 188 SIEFLAFFSPSGVNCAQQYFTSRQLSMDKWKLVAIGPSTRRALESLGQKVYCTAERPTVE 247

Query: 234 SLVESVL 240
            LV+ +L
Sbjct: 248 HLVKVLL 254


>AE014297-2078|AAF55222.1|  253|Drosophila melanogaster CG9589-PA
           protein.
          Length = 253

 Score = 83.8 bits (198), Expect = 2e-16
 Identities = 65/247 (26%), Positives = 113/247 (45%), Gaps = 14/247 (5%)

Query: 3   IVLFKGESED--YQRIFRENNFETIFVEPLQFIYINIEELSQKLLQ-NDYDGMILTSPRA 59
           ++L K  S D  Y    R +N + IF+ P  F++ N+++L  KL + + Y G+I  SPR 
Sbjct: 9   VILLKVPSSDDFYGSALRSHNLDPIFITPSHFVFKNLKQLQAKLHEPHKYAGIIFASPRC 68

Query: 60  VEAVSKCWDPTKFV-IWNSKDVYTVGEMS-SQKIKXXXXXXXXXXXXXNAENLSKIILKD 117
           V+AV++    T     W +   Y++G+ + S                 NA NL  +I++ 
Sbjct: 69  VQAVNEALGKTPLPSCWRALHNYSLGKNTHSAAWITFQNLPTLGDHAVNANNLCDLIVET 128

Query: 118 --KKKTSTFLFPCGNLRSETIPNMLQSEGITLDAITVYETQENENLKALLMELNNLNDSP 175
              K+    L PCGN   +T+   L ++G  +DA  VYE++ + +    +          
Sbjct: 129 FGPKRDLPLLMPCGNGVGQTLRLRLVAQGFRVDACEVYESRSHPDFVNQMRHALKFKRME 188

Query: 176 SGLAFFSPSGCEYIHRQLQTFSN-RLSLLPH--FAIGNSTAHKIENLGVEIAGVAAKPKA 232
           + + FF PS    +   L+ F N  +SL      A+G+ T   +E  G++  GV      
Sbjct: 189 T-IVFFGPSS---VRSSLEFFGNYNVSLKDRKLIAVGSGTRKAMEESGIKADGVVNAADV 244

Query: 233 ESLVESV 239
           + L+  +
Sbjct: 245 DRLINII 251


>BT001564-1|AAN71319.1|  578|Drosophila melanogaster RE16347p
           protein.
          Length = 578

 Score = 30.3 bits (65), Expect = 2.6
 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 4/46 (8%)

Query: 132 RSETIPN-MLQSEGIT---LDAITVYETQENENLKALLMELNNLND 173
           + E  PN  L ++ IT   L+ +++++TQE+E L+ L  ELN+L D
Sbjct: 298 KMEESPNDTLTADAITSDMLENLSIHDTQESEMLRLLNAELNDLLD 343


>BT001318-1|AAN71073.1|  633|Drosophila melanogaster AT15149p
           protein.
          Length = 633

 Score = 30.3 bits (65), Expect = 2.6
 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 4/46 (8%)

Query: 132 RSETIPN-MLQSEGIT---LDAITVYETQENENLKALLMELNNLND 173
           + E  PN  L ++ IT   L+ +++++TQE+E L+ L  ELN+L D
Sbjct: 45  KMEESPNDTLTADAITSDMLENLSIHDTQESEMLRLLNAELNDLLD 90


>AY061832-1|AAL27643.1|  564|Drosophila melanogaster SD06513p
           protein.
          Length = 564

 Score = 30.3 bits (65), Expect = 2.6
 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 4/46 (8%)

Query: 132 RSETIPN-MLQSEGIT---LDAITVYETQENENLKALLMELNNLND 173
           + E  PN  L ++ IT   L+ +++++TQE+E L+ L  ELN+L D
Sbjct: 284 KMEESPNDTLTADAITSDMLENLSIHDTQESEMLRLLNAELNDLLD 329


>AY058508-1|AAL13737.1|  522|Drosophila melanogaster LD21426p
           protein.
          Length = 522

 Score = 30.3 bits (65), Expect = 2.6
 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 1/66 (1%)

Query: 150 ITVYETQENENLKALLMELNNLNDSPSGLAFFSPSGCEYIHRQLQTFS-NRLSLLPHFAI 208
           I + E   NE + AL      +  +P+  A+ SP G  Y+ +QLQ  + N + L  +   
Sbjct: 136 IVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNA 195

Query: 209 GNSTAH 214
           GN  AH
Sbjct: 196 GNPLAH 201


>AE014298-3078|AAF50863.1|  522|Drosophila melanogaster CG1753-PB,
           isoform B protein.
          Length = 522

 Score = 30.3 bits (65), Expect = 2.6
 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 1/66 (1%)

Query: 150 ITVYETQENENLKALLMELNNLNDSPSGLAFFSPSGCEYIHRQLQTFS-NRLSLLPHFAI 208
           I + E   NE + AL      +  +P+  A+ SP G  Y+ +QLQ  + N + L  +   
Sbjct: 136 IVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNA 195

Query: 209 GNSTAH 214
           GN  AH
Sbjct: 196 GNPLAH 201


>AE014298-3077|AAF50862.1|  522|Drosophila melanogaster CG1753-PA,
           isoform A protein.
          Length = 522

 Score = 30.3 bits (65), Expect = 2.6
 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 1/66 (1%)

Query: 150 ITVYETQENENLKALLMELNNLNDSPSGLAFFSPSGCEYIHRQLQTFS-NRLSLLPHFAI 208
           I + E   NE + AL      +  +P+  A+ SP G  Y+ +QLQ  + N + L  +   
Sbjct: 136 IVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNA 195

Query: 209 GNSTAH 214
           GN  AH
Sbjct: 196 GNPLAH 201


>AE014134-2584|ABC65906.1|  348|Drosophila melanogaster CG31732-PH,
           isoform H protein.
          Length = 348

 Score = 30.3 bits (65), Expect = 2.6
 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 4/46 (8%)

Query: 132 RSETIPN-MLQSEGIT---LDAITVYETQENENLKALLMELNNLND 173
           + E  PN  L ++ IT   L+ +++++TQE+E L+ L  ELN+L D
Sbjct: 68  KMEESPNDTLTADAITSDMLENLSIHDTQESEMLRLLNAELNDLLD 113


>AE014134-2583|AAN10894.1|  564|Drosophila melanogaster CG31732-PD,
           isoform D protein.
          Length = 564

 Score = 30.3 bits (65), Expect = 2.6
 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 4/46 (8%)

Query: 132 RSETIPN-MLQSEGIT---LDAITVYETQENENLKALLMELNNLND 173
           + E  PN  L ++ IT   L+ +++++TQE+E L+ L  ELN+L D
Sbjct: 284 KMEESPNDTLTADAITSDMLENLSIHDTQESEMLRLLNAELNDLLD 329


>AE014134-2582|AAF53447.2|  578|Drosophila melanogaster CG31732-PC,
           isoform C protein.
          Length = 578

 Score = 30.3 bits (65), Expect = 2.6
 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 4/46 (8%)

Query: 132 RSETIPN-MLQSEGIT---LDAITVYETQENENLKALLMELNNLND 173
           + E  PN  L ++ IT   L+ +++++TQE+E L+ L  ELN+L D
Sbjct: 298 KMEESPNDTLTADAITSDMLENLSIHDTQESEMLRLLNAELNDLLD 343


>AE014134-2579|ABC65903.1|  660|Drosophila melanogaster CG31732-PF,
           isoform F protein.
          Length = 660

 Score = 30.3 bits (65), Expect = 2.6
 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 4/46 (8%)

Query: 132 RSETIPN-MLQSEGIT---LDAITVYETQENENLKALLMELNNLND 173
           + E  PN  L ++ IT   L+ +++++TQE+E L+ L  ELN+L D
Sbjct: 68  KMEESPNDTLTADAITSDMLENLSIHDTQESEMLRLLNAELNDLLD 113


>AE014134-2578|AAF53449.4|  890|Drosophila melanogaster CG31732-PB,
           isoform B protein.
          Length = 890

 Score = 30.3 bits (65), Expect = 2.6
 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 4/46 (8%)

Query: 132 RSETIPN-MLQSEGIT---LDAITVYETQENENLKALLMELNNLND 173
           + E  PN  L ++ IT   L+ +++++TQE+E L+ L  ELN+L D
Sbjct: 298 KMEESPNDTLTADAITSDMLENLSIHDTQESEMLRLLNAELNDLLD 343


>AE014134-2581|ABC65905.1|  738|Drosophila melanogaster CG31732-PG,
           isoform G protein.
          Length = 738

 Score = 29.9 bits (64), Expect = 3.4
 Identities = 18/44 (40%), Positives = 29/44 (65%), Gaps = 4/44 (9%)

Query: 134 ETIPN-MLQSEGIT---LDAITVYETQENENLKALLMELNNLND 173
           E  PN  L ++ IT   L+ +++++TQE+E L+ L  ELN+L D
Sbjct: 2   EESPNDTLTADAITSDMLENLSIHDTQESEMLRLLNAELNDLLD 45


>AE014134-2580|ABC65904.1|  592|Drosophila melanogaster CG31732-PE,
           isoform E protein.
          Length = 592

 Score = 29.9 bits (64), Expect = 3.4
 Identities = 18/44 (40%), Positives = 29/44 (65%), Gaps = 4/44 (9%)

Query: 134 ETIPN-MLQSEGIT---LDAITVYETQENENLKALLMELNNLND 173
           E  PN  L ++ IT   L+ +++++TQE+E L+ L  ELN+L D
Sbjct: 2   EESPNDTLTADAITSDMLENLSIHDTQESEMLRLLNAELNDLLD 45


>AY071192-1|AAL48814.1|  689|Drosophila melanogaster RE24065p
           protein.
          Length = 689

 Score = 29.5 bits (63), Expect = 4.6
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 7/77 (9%)

Query: 124 FLFPCGNLRSETIPNMLQSEG--ITLDAITVYETQENENLKALLMELNNLNDSPSGLAF- 180
           +L P      ETI   L  +     +D I+VY+  +NEN   +L   + LN  PS +   
Sbjct: 221 YLDPIRQYNKETIELELPGDKTIFDIDWISVYDVADNENYGHVLFN-DKLNVPPSLVKVT 279

Query: 181 ---FSPSGCEYIHRQLQ 194
              FS   C  +H+ +Q
Sbjct: 280 PFEFSLPNCRQLHKDMQ 296


>AE014297-1097|AAF54497.1|  689|Drosophila melanogaster CG6217-PA
           protein.
          Length = 689

 Score = 29.5 bits (63), Expect = 4.6
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 7/77 (9%)

Query: 124 FLFPCGNLRSETIPNMLQSEG--ITLDAITVYETQENENLKALLMELNNLNDSPSGLAF- 180
           +L P      ETI   L  +     +D I+VY+  +NEN   +L   + LN  PS +   
Sbjct: 221 YLDPIRQYNKETIELELPGDKTIFDIDWISVYDVADNENYGHVLFN-DKLNVPPSLVKVT 279

Query: 181 ---FSPSGCEYIHRQLQ 194
              FS   C  +H+ +Q
Sbjct: 280 PFEFSLPNCRQLHKDMQ 296


>BT001640-1|AAN71395.1|  475|Drosophila melanogaster RE40923p
           protein.
          Length = 475

 Score = 29.1 bits (62), Expect = 6.0
 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 4/82 (4%)

Query: 111 SKIILKDKKKTSTFLFPCGNLRSETIPNMLQSEGITL----DAITVYETQENENLKALLM 166
           +KII   K   S F      LRS    + L+ + +      D +  YE    +   AL +
Sbjct: 383 TKIIFNAKGTLSIFTEKVDILRSGNCESFLKLKNLKKIFVPDNMIKYEKATLDRFLALGV 442

Query: 167 ELNNLNDSPSGLAFFSPSGCEY 188
           EL + N + SGL   S SG +Y
Sbjct: 443 ELIDYNSASSGLESVSDSGPDY 464


>AE014296-2218|AAN11841.1|  475|Drosophila melanogaster CG32115-PA
           protein.
          Length = 475

 Score = 29.1 bits (62), Expect = 6.0
 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 4/82 (4%)

Query: 111 SKIILKDKKKTSTFLFPCGNLRSETIPNMLQSEGITL----DAITVYETQENENLKALLM 166
           +KII   K   S F      LRS    + L+ + +      D +  YE    +   AL +
Sbjct: 383 TKIIFNAKGTLSIFTEKVDILRSGNCESFLKLKNLKKIFVPDNMIKYEKATLDRFLALGV 442

Query: 167 ELNNLNDSPSGLAFFSPSGCEY 188
           EL + N + SGL   S SG +Y
Sbjct: 443 ELIDYNSASSGLESVSDSGPDY 464


  Database: fruitfly
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 24,830,863
  Number of sequences in database:  52,641
  
Lambda     K      H
   0.316    0.133    0.374 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 10,328,893
Number of Sequences: 52641
Number of extensions: 385026
Number of successful extensions: 961
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 938
Number of HSP's gapped (non-prelim): 20
length of query: 248
length of database: 24,830,863
effective HSP length: 83
effective length of query: 165
effective length of database: 20,461,660
effective search space: 3376173900
effective search space used: 3376173900
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 61 (28.7 bits)

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