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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000197-TA|BGIBMGA000197-PA|IPR003754|Uroporphyrinogen
III synthase HEM4
         (248 letters)

Database: spombe 
           5004 sequences; 2,362,478 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SPAC31G5.08 |ups1|ups|uroporphyrinogen-III synthase Ups1|Schizos...    57   2e-09
SPBC119.17 ||SPBC577.01|metallopeptidase|Schizosaccharomyces pom...    31   0.16 
SPBC3E7.01 |fab1|ste12, SPBC6B1.11c|1-phosphatidylinositol-3-pho...    31   0.21 
SPBC25H2.03 |||vacuolar protein involved in phosphoinositide met...    30   0.27 
SPAC3H1.03 |mug151||transcriptional regulator, HCNGP-like |Schiz...    27   1.9  
SPCC16C4.09 |sts5|orb4|RNB-like protein|Schizosaccharomyces pomb...    27   2.6  
SPAC23H4.14 |vam6|vps39|guanyl-nucleotide exchange factor Vma6|S...    27   2.6  
SPBC1198.11c |reb1|SPBC660.01c|RNA polymerase I transcription te...    27   3.4  
SPAC1565.04c |ste4||adaptor protein Ste4|Schizosaccharomyces pom...    26   4.5  
SPAC13F5.05 |||thioredoxin family protein|Schizosaccharomyces po...    26   4.5  
SPAC30C2.03 |||sequence orphan|Schizosaccharomyces pombe|chr 1||...    26   4.5  
SPBPJ4664.04 |||coatomer alpha subunit |Schizosaccharomyces pomb...    26   5.9  
SPAC2G11.05c |||BRO1 domain protein|Schizosaccharomyces pombe|ch...    26   5.9  
SPAC1705.03c ||SPAC23H4.19|conserved fungal family|Schizosacchar...    25   7.8  
SPAC18B11.02c |||pseudouridylate synthase |Schizosaccharomyces p...    25   7.8  
SPAC144.15c |cog1||Golgi transport complex subunit Cog1 |Schizos...    25   7.8  
SPAC29A4.19c |||P-type ATPase |Schizosaccharomyces pombe|chr 1||...    25   7.8  
SPAC2E1P3.01 |||zinc binding dehydrogenase|Schizosaccharomyces p...    25   7.8  

>SPAC31G5.08 |ups1|ups|uroporphyrinogen-III synthase
           Ups1|Schizosaccharomyces pombe|chr 1|||Manual
          Length = 251

 Score = 57.2 bits (132), Expect = 2e-09
 Identities = 58/241 (24%), Positives = 104/241 (43%), Gaps = 19/241 (7%)

Query: 11  EDYQRIFRENNFETIFVEPLQFIYINIEELSQKL--LQNDYDGMILTSPRAVEAVSKCW- 67
           + Y   F +   +T F+  L+   ++ E+L  KL  ++  Y G+I+TS R  E + +   
Sbjct: 15  DPYVEAFEKYGRDTAFIPVLRHKRVHEEQLRDKLKNVRKTYCGLIVTSQRVSETLDEALK 74

Query: 68  --DPT-KFVIWNSKDVYTVGEMSSQKIKXXXXXXXXXXXXXNAENLSKIILK---DKKKT 121
             D T +  I     ++TVG  +   I+               E L+ +I +     K+ 
Sbjct: 75  QEDETERQKILMETPIFTVGPATDDSIRRLGFQQTHGKDCGRGEVLADLIEEWYTTTKQH 134

Query: 122 STFLFPCGNLRSETIPNMLQSEGITLDAITVYETQENENLKALLMELNNLNDSPSGLAFF 181
              LF  G    + I   L  + +  D++ VY TQE EN +  + +    + +   +  F
Sbjct: 135 KPLLFLVGEKHRDIIQRKLGDDRV--DSLIVYATQELENTETQIKDTIRKHPTIDWIVAF 192

Query: 182 SPSGCEYIHRQLQTFSNRLSLLPHFAIGNSTAHKIENLGVEIAGVAAKPKAESLVESVLK 241
           SP+    I   L TF  +++      IG +T   ++ LG +   V+  P  ESL  S++ 
Sbjct: 193 SPTS---ICSLLNTFELKIA-----TIGPTTGDYLKKLGTQPNVVSPAPNPESLASSIVA 244

Query: 242 Y 242
           +
Sbjct: 245 F 245


>SPBC119.17 ||SPBC577.01|metallopeptidase|Schizosaccharomyces
           pombe|chr 2|||Manual
          Length = 992

 Score = 31.1 bits (67), Expect = 0.16
 Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 1/55 (1%)

Query: 189 IHRQLQTFSNRLSLLPHFAIGNSTAHKIENLGVEIAGVAAKPKAESLVESVLKYF 243
           +  Q++ ++  +S+ P     NS   K E LG+ I+G A       LVE + K F
Sbjct: 617 LEHQIRRYTGGISISPSAVTNNSDVSKYE-LGIAISGYALDKNVGKLVELINKAF 670



 Score = 25.4 bits (53), Expect = 7.8
 Identities = 14/44 (31%), Positives = 24/44 (54%)

Query: 204 PHFAIGNSTAHKIENLGVEIAGVAAKPKAESLVESVLKYFALQG 247
           P+    ++T   I ++G+E A   +  K E+LV S+    AL+G
Sbjct: 361 PNSGYDSTTKRGIFSVGLEGASEESLAKIENLVYSIFNDLALKG 404


>SPBC3E7.01 |fab1|ste12,
            SPBC6B1.11c|1-phosphatidylinositol-3-phosphate 5-kinase
            Fab1 |Schizosaccharomyces pombe|chr 2|||Manual
          Length = 1932

 Score = 30.7 bits (66), Expect = 0.21
 Identities = 18/61 (29%), Positives = 30/61 (49%)

Query: 173  DSPSGLAFFSPSGCEYIHRQLQTFSNRLSLLPHFAIGNSTAHKIENLGVEIAGVAAKPKA 232
            D PS L  F+ S  +Y+ + ++   +    L +  +  ST  KIENL ++  G   K + 
Sbjct: 1592 DEPSSLISFTLSSPDYLSKMVEIEDSMDEALTNQGLQGSTQFKIENLMLKPTGTHLKYQF 1651

Query: 233  E 233
            E
Sbjct: 1652 E 1652


>SPBC25H2.03 |||vacuolar protein involved in phosphoinositide
           metabolism|Schizosaccharomyces pombe|chr 2|||Manual
          Length = 811

 Score = 30.3 bits (65), Expect = 0.27
 Identities = 20/70 (28%), Positives = 38/70 (54%), Gaps = 6/70 (8%)

Query: 108 ENLSKIILKDKKKTSTFLFPCGNLRSETIPNMLQSEGITLDAITVYETQENENLKALLME 167
           ++L ++  +D+K    FL   GNL    + N ++ E +      + ET+EN  L ++++E
Sbjct: 518 KSLLQMFAEDRK----FLNSRGNLIIRQLCNYIEGERVYTSFAGILETEENLELASIMVE 573

Query: 168 L--NNLNDSP 175
           +  NNL  +P
Sbjct: 574 VLNNNLFTAP 583


>SPAC3H1.03 |mug151||transcriptional regulator, HCNGP-like
           |Schizosaccharomyces pombe|chr 1|||Manual
          Length = 146

 Score = 27.5 bits (58), Expect = 1.9
 Identities = 17/47 (36%), Positives = 20/47 (42%), Gaps = 4/47 (8%)

Query: 43  KLLQNDYDGMILTSPRAVEAVSKCWDPTKFVIWNSKDVYTVGEMSSQ 89
           KLL N  D + +  PR        WDPT F     K+VY      SQ
Sbjct: 77  KLLDNLQDFLDIKEPRGTMISKDMWDPTDF----HKNVYASALSKSQ 119


>SPCC16C4.09 |sts5|orb4|RNB-like protein|Schizosaccharomyces
           pombe|chr 3|||Manual
          Length = 1066

 Score = 27.1 bits (57), Expect = 2.6
 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 4/82 (4%)

Query: 117 DKKKTSTFLFPCGNLRSETIPNMLQSEGITLDAITVYETQENE-NLKALLMELNNLNDSP 175
           D   T + L     +  +T+ N+LQ     +    VYE Q+ + NL + +M L   ++S 
Sbjct: 849 DLSSTKSLLRSLSLIEDDTVRNILQLYYYKVTPRAVYEMQKYKGNLASQMMSLGIEDESD 908

Query: 176 SGLAFFSP---SGCEYIHRQLQ 194
               F +P    G   +H QLQ
Sbjct: 909 DLTHFTAPLERYGDIVVHYQLQ 930


>SPAC23H4.14 |vam6|vps39|guanyl-nucleotide exchange factor
           Vma6|Schizosaccharomyces pombe|chr 1|||Manual
          Length = 905

 Score = 27.1 bits (57), Expect = 2.6
 Identities = 14/35 (40%), Positives = 21/35 (60%), Gaps = 2/35 (5%)

Query: 150 ITVYETQENENLKALLMELNNLNDSPSGLAFFSPS 184
           + +YE Q+N   K  L +  +LND P  LA+ SP+
Sbjct: 126 LEIYEIQKNS--KPNLTKTISLNDRPRSLAWVSPT 158


>SPBC1198.11c |reb1|SPBC660.01c|RNA polymerase I transcription
           termination factor Reb1|Schizosaccharomyces pombe|chr
           2|||Manual
          Length = 504

 Score = 26.6 bits (56), Expect = 3.4
 Identities = 15/60 (25%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 156 QENENLKALLMELNNLNDSPSGLAFFSPSGCEYIHRQLQTFSNRLSLLPHFAIGNSTAHK 215
           Q N+++     E+ N++    G A ++    +Y+ R++Q F    S L H  + +S   K
Sbjct: 131 QTNDSILISPSEITNMDPFLKGSARWTAEHWDYLERRMQNFCQTYS-LDHTQVADSLHEK 189


>SPAC1565.04c |ste4||adaptor protein Ste4|Schizosaccharomyces
           pombe|chr 1|||Manual
          Length = 264

 Score = 26.2 bits (55), Expect = 4.5
 Identities = 14/49 (28%), Positives = 27/49 (55%)

Query: 9   ESEDYQRIFRENNFETIFVEPLQFIYINIEELSQKLLQNDYDGMILTSP 57
           E+E+ + +   N+  + F++ L+ I IN++E  Q   +N  D   +T P
Sbjct: 119 ETENTKLVKTLNSLNSEFLQLLRKIAINVKEGRQLTTENSSDTSSMTHP 167


>SPAC13F5.05 |||thioredoxin family protein|Schizosaccharomyces
           pombe|chr 1|||Manual
          Length = 363

 Score = 26.2 bits (55), Expect = 4.5
 Identities = 22/103 (21%), Positives = 43/103 (41%), Gaps = 6/103 (5%)

Query: 83  VGEMSSQKIKXXXXXXXXXXXXXNAENLSKIILKDKKKTSTFLFPCGNLRSETIP-NMLQ 141
           V +    K+K             +A+N SK+IL  +K   T L+   +    ++P + + 
Sbjct: 138 VSDSIPSKVKILTSEAKTQKFIQDAQNSSKVILISQKMKPTLLYKSLSNEFSSLPFSFMP 197

Query: 142 SEGITLDAITVYETQENENLKALLMELNNLNDSPSGLAFFSPS 184
           ++    D   +    +  +L  L ++  N     +G +FFS S
Sbjct: 198 AKANVNDLFNISAYVDTSDLPILFIKHPN-----NGTSFFSNS 235


>SPAC30C2.03 |||sequence orphan|Schizosaccharomyces pombe|chr
           1|||Manual
          Length = 210

 Score = 26.2 bits (55), Expect = 4.5
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 2/38 (5%)

Query: 128 CGNLRSETIPNMLQSEGITLDAITVYETQENENLKALL 165
           C NL  ET+      + + L A+  YE Q+  NLK LL
Sbjct: 153 CVNLPPETL--FYDMQRLWLTAMNTYENQKPPNLKLLL 188


>SPBPJ4664.04 |||coatomer alpha subunit |Schizosaccharomyces
           pombe|chr 2|||Manual
          Length = 1207

 Score = 25.8 bits (54), Expect = 5.9
 Identities = 34/152 (22%), Positives = 62/152 (40%), Gaps = 16/152 (10%)

Query: 81  YTVGEMSSQKIKXXXXXXXXXXXXXNAENLSKI-ILKDKKKTSTFLFPCGNLRSETIP-- 137
           + + E++ QK++             NAE L K+ I+ +K+  +  LF      +E     
Sbjct: 694 HKIAEITFQKLRYFEKLSFLYLITGNAEKLQKMAIIAEKRNDTLSLFQNSLYLNEVESRI 753

Query: 138 NMLQSEGI-TLDAITVYETQENENLKALLMELNNLNDS---PS-GLAFFSPSGCEYIHRQ 192
           N+L+  G+  +  +T       E  + +L   N   +    PS G AF +P         
Sbjct: 754 NILEQAGMYPIAYLTAKSNGLEEKAQQILSHCNKTEEEIKLPSLGSAFTTPVPVN----- 808

Query: 193 LQTFSNRLSLL--PHFAIGNSTAHKIENLGVE 222
            +T+++   LL   H     S   ++E L +E
Sbjct: 809 -ETYTHNWPLLDTSHSTFEKSLQERMEQLAIE 839


>SPAC2G11.05c |||BRO1 domain protein|Schizosaccharomyces pombe|chr
           1|||Manual
          Length = 701

 Score = 25.8 bits (54), Expect = 5.9
 Identities = 19/95 (20%), Positives = 37/95 (38%), Gaps = 1/95 (1%)

Query: 42  QKLLQNDYDGMILTSPRA-VEAVSKCWDPTKFVIWNSKDVYTVGEMSSQKIKXXXXXXXX 100
           +KL  NDY  + + S    + ++ KC+       WN +      E+  Q ++        
Sbjct: 550 KKLGSNDYFNISMYSNHTDIHSLLKCFREAVDAKWNFRRQRERQEIIIQNVEKLKSYLNS 609

Query: 101 XXXXXNAENLSKIILKDKKKTSTFLFPCGNLRSET 135
                    +SKI+   ++    + F    +R+ET
Sbjct: 610 FKVQAECSEISKILSFSQETEKKYKFLLQTVRNET 644


>SPAC1705.03c ||SPAC23H4.19|conserved fungal
           family|Schizosaccharomyces pombe|chr 1|||Manual
          Length = 421

 Score = 25.4 bits (53), Expect = 7.8
 Identities = 8/25 (32%), Positives = 17/25 (68%)

Query: 143 EGITLDAITVYETQENENLKALLME 167
           +GI+LD++T ++   N  ++ + ME
Sbjct: 153 DGISLDSVTTFQVTNNRYIQEITME 177


>SPAC18B11.02c |||pseudouridylate synthase |Schizosaccharomyces
           pombe|chr 1|||Manual
          Length = 394

 Score = 25.4 bits (53), Expect = 7.8
 Identities = 15/34 (44%), Positives = 17/34 (50%)

Query: 151 TVYETQENENLKALLMELNNLNDSPSGLAFFSPS 184
           TV      EN  +LL   N L+   SGL FFS S
Sbjct: 135 TVLHILMKENKCSLLYPCNRLDRLTSGLMFFSKS 168


>SPAC144.15c |cog1||Golgi transport complex subunit Cog1
           |Schizosaccharomyces pombe|chr 1|||Manual
          Length = 701

 Score = 25.4 bits (53), Expect = 7.8
 Identities = 14/46 (30%), Positives = 22/46 (47%)

Query: 36  NIEELSQKLLQNDYDGMILTSPRAVEAVSKCWDPTKFVIWNSKDVY 81
           NI    +K+LQN Y+   + S   V+ VSK     + +   S D +
Sbjct: 64  NIRNNLEKVLQNSYEFQSMVSLPKVDRVSKFLSDNESISQTSGDYF 109


>SPAC29A4.19c |||P-type ATPase |Schizosaccharomyces pombe|chr
           1|||Manual
          Length = 1096

 Score = 25.4 bits (53), Expect = 7.8
 Identities = 11/25 (44%), Positives = 16/25 (64%)

Query: 108 ENLSKIILKDKKKTSTFLFPCGNLR 132
           E +S I LK+  +TS+F+ P G  R
Sbjct: 101 EKVSSICLKNDIQTSSFVLPSGKTR 125


>SPAC2E1P3.01 |||zinc binding dehydrogenase|Schizosaccharomyces
           pombe|chr 1|||Manual
          Length = 348

 Score = 25.4 bits (53), Expect = 7.8
 Identities = 15/43 (34%), Positives = 23/43 (53%)

Query: 12  DYQRIFRENNFETIFVEPLQFIYINIEELSQKLLQNDYDGMIL 54
           DY    RE NF    +EP+Q  Y +  E+ +KL     +G+I+
Sbjct: 270 DYSLFNREFNFFGNKIEPIQASYDHAVEVYKKLTGWLQEGVII 312


  Database: spombe
    Posted date:  Oct 3, 2007  3:31 PM
  Number of letters in database: 2,362,478
  Number of sequences in database:  5004
  
Lambda     K      H
   0.316    0.133    0.374 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,051,513
Number of Sequences: 5004
Number of extensions: 41440
Number of successful extensions: 119
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 106
Number of HSP's gapped (non-prelim): 20
length of query: 248
length of database: 2,362,478
effective HSP length: 71
effective length of query: 177
effective length of database: 2,007,194
effective search space: 355273338
effective search space used: 355273338
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 53 (25.4 bits)

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