Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000189-TA|BGIBMGA000189-PA|IPR000357|HEAT
(680 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC125109-1|AAI25110.1| 782|Homo sapiens Vac14 homolog (S. cerev... 328 5e-89
BC125108-1|AAI25109.1| 782|Homo sapiens Vac14 homolog (S. cerev... 328 5e-89
CR457343-1|CAG33624.1| 524|Homo sapiens FLJ10305 protein. 207 1e-52
BC007214-1|AAH07214.2| 575|Homo sapiens VAC14 protein protein. 207 1e-52
BC000536-1|AAH00536.2| 356|Homo sapiens VAC14 protein protein. 207 1e-52
AK025479-1|BAB15145.1| 524|Homo sapiens protein ( Homo sapiens ... 207 1e-52
AK001167-1|BAA91530.1| 347|Homo sapiens protein ( Homo sapiens ... 206 2e-52
U25801-1|AAB03813.1| 167|Homo sapiens Tax1 binding protein prot... 97 2e-19
AF054284-1|AAC97189.1| 1304|Homo sapiens spliceosomal protein SA... 34 1.4
BC072420-1|AAH72420.1| 887|Homo sapiens transportin 2 (importin... 33 2.5
BC018314-1|AAH18314.1| 771|Homo sapiens Unknown (protein for IM... 33 2.5
AF019039-1|AAB83973.1| 896|Homo sapiens transportin2 protein. 33 2.5
AF007748-1|AAB71349.1| 887|Homo sapiens karyopherin beta2b homo... 33 2.5
AB210011-1|BAE06093.1| 1051|Homo sapiens TNPO2 variant protein p... 33 2.5
U72395-1|AAB68948.1| 890|Homo sapiens MIP protein. 32 5.8
U72069-1|AAB58254.1| 890|Homo sapiens karyopherin beta2 protein. 32 5.8
U70322-1|AAC50723.1| 890|Homo sapiens transportin protein. 32 5.8
BC047240-1|AAH47240.1| 855|Homo sapiens HEAT repeat containing ... 32 5.8
BC040340-1|AAH40340.1| 890|Homo sapiens transportin 1 protein. 32 5.8
AK000404-1|BAA91142.1| 235|Homo sapiens protein ( Homo sapiens ... 32 5.8
U77700-1|AAC51648.1| 1928|Homo sapiens HsGCN1 protein. 32 7.7
>BC125109-1|AAI25110.1| 782|Homo sapiens Vac14 homolog (S.
cerevisiae) protein.
Length = 782
Score = 328 bits (805), Expect = 5e-89
Identities = 166/331 (50%), Positives = 227/331 (68%), Gaps = 16/331 (4%)
Query: 3 ERDYAPLSIACVRGLCDKLYEKRKVAGVEIEKMVKDFNDAKNTSQIKKLIKVLGQDLMSS 62
E+D+APL+ VR L DKLYEKRKVA +EIEK+V++F NT QIK +I+ L Q+ S
Sbjct: 4 EKDFAPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNTVQIKHVIQTLSQEFALS 63
Query: 63 TNPNMKNGALMGLSTVAVGLGKASVDYLPELTNPIVACFSESESRVRYQAAEALFN---- 118
+P+ + G L+GL+ ++ LGK S YL EL P++ CF++++SR+RY A EAL+N
Sbjct: 64 QHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKV 123
Query: 119 --------FPVIFDALAKLAADPEQQVKHAAELLDRLLKDIVTXXXXXXXXXXXXXXRER 170
F V+FD L+KLAADP+ VK +ELLDRLLKDIVT RER
Sbjct: 124 ARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVSFIPLLRER 183
Query: 171 MYTRSAPARQLAVSWVAVLDAVPDLNVLAHLPDLLDGLFKMLDDPNPEIRRMCDVQLNEF 230
+Y+ + ARQ +SW+ VL++VPD+N+L +LP++LDGLF++L D EIR+MC+V L EF
Sbjct: 184 IYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEF 243
Query: 231 LRSIKKEPAKVDFQAMINILIIHAQSPEELLQLTAITWLKEFVELAGAAMLPFASGILCA 290
L+ IKK P+ V F M NIL+IH Q+ ++L+QLTA+ W++EF++LAG MLP++SGIL A
Sbjct: 244 LKEIKKNPSSVKFAEMANILVIHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTA 303
Query: 291 VLPCHAYSDEPRKKRTGIRETAATVNFQLIK 321
VLPC AY D RKK I+E A N L+K
Sbjct: 304 VLPCLAYDD--RKK--SIKEVANVCNQSLMK 330
Score = 207 bits (505), Expect = 1e-52
Identities = 112/252 (44%), Positives = 149/252 (59%), Gaps = 3/252 (1%)
Query: 416 CSAAGDLQSSPYYYKFLQAXXXXXXXXXXXXXXXGAFIIRQLCVLLNAEDIYRALANILQ 475
CS + +S Y+YKF+ G FIIRQLC+LLNAE+I+ ++A+IL
Sbjct: 516 CSPSTPTMNS-YFYKFMINLLKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILL 574
Query: 476 QEKNLRFVTTMVDILNTILLTSAELYELRALLKDRSKPWSRSLFLALHGCWCHSPVSLLA 535
+E++L+F +TMV LNTILLTS EL++LR LKD S++LF L+ WCH+PV+ ++
Sbjct: 575 REEDLKFASTMVHALNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVS 634
Query: 536 LCLLAHHYRHCNTLIATFGDLEITVEFLTEVDKLVQLIESPIFAYLRLELVG-EHSXXXX 594
LC L +YRH LI FGDLE+TV+FL EVDKLVQLIE PIF YLRL+L+ +++
Sbjct: 635 LCFLTQNYRHAYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLI 694
Query: 595 XXXXXXXXXXPQSDAFHALRARLHCLPPPHQPHRPRG-DEREGSEAADDEPLDYGALLAQ 653
PQS AF L RL C+P P S+ AD +DY LL
Sbjct: 695 KALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDSLKAAPKSQKADSPSIDYAELLQH 754
Query: 654 FHAVQAQHRQYR 665
F VQ +H + R
Sbjct: 755 FEKVQNKHLEVR 766
Score = 48.0 bits (109), Expect = 1e-04
Identities = 22/64 (34%), Positives = 38/64 (59%)
Query: 363 TKVAALDWILHLYNKLPKQMCGETERVWAGAVGSLTDAAHDVLRRALAVLAEICSAAGDL 422
T++A L W+ HLY K P++M T+ ++ + +L+D + +V+ + L VLAEI S+
Sbjct: 417 TRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVILKDLEVLAEIASSPAGQ 476
Query: 423 QSSP 426
P
Sbjct: 477 TDDP 480
>BC125108-1|AAI25109.1| 782|Homo sapiens Vac14 homolog (S.
cerevisiae) protein.
Length = 782
Score = 328 bits (805), Expect = 5e-89
Identities = 166/331 (50%), Positives = 227/331 (68%), Gaps = 16/331 (4%)
Query: 3 ERDYAPLSIACVRGLCDKLYEKRKVAGVEIEKMVKDFNDAKNTSQIKKLIKVLGQDLMSS 62
E+D+APL+ VR L DKLYEKRKVA +EIEK+V++F NT QIK +I+ L Q+ S
Sbjct: 4 EKDFAPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNTVQIKHVIQTLSQEFALS 63
Query: 63 TNPNMKNGALMGLSTVAVGLGKASVDYLPELTNPIVACFSESESRVRYQAAEALFN---- 118
+P+ + G L+GL+ ++ LGK S YL EL P++ CF++++SR+RY A EAL+N
Sbjct: 64 QHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKV 123
Query: 119 --------FPVIFDALAKLAADPEQQVKHAAELLDRLLKDIVTXXXXXXXXXXXXXXRER 170
F V+FD L+KLAADP+ VK +ELLDRLLKDIVT RER
Sbjct: 124 ARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVSFIPLLRER 183
Query: 171 MYTRSAPARQLAVSWVAVLDAVPDLNVLAHLPDLLDGLFKMLDDPNPEIRRMCDVQLNEF 230
+Y+ + ARQ +SW+ VL++VPD+N+L +LP++LDGLF++L D EIR+MC+V L EF
Sbjct: 184 IYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEF 243
Query: 231 LRSIKKEPAKVDFQAMINILIIHAQSPEELLQLTAITWLKEFVELAGAAMLPFASGILCA 290
L+ IKK P+ V F M NIL+IH Q+ ++L+QLTA+ W++EF++LAG MLP++SGIL A
Sbjct: 244 LKEIKKNPSSVKFAEMANILVIHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTA 303
Query: 291 VLPCHAYSDEPRKKRTGIRETAATVNFQLIK 321
VLPC AY D RKK I+E A N L+K
Sbjct: 304 VLPCLAYDD--RKK--SIKEVANVCNQSLMK 330
Score = 207 bits (505), Expect = 1e-52
Identities = 112/252 (44%), Positives = 149/252 (59%), Gaps = 3/252 (1%)
Query: 416 CSAAGDLQSSPYYYKFLQAXXXXXXXXXXXXXXXGAFIIRQLCVLLNAEDIYRALANILQ 475
CS + +S Y+YKF+ G FIIRQLC+LLNAE+I+ ++A+IL
Sbjct: 516 CSPSTPTMNS-YFYKFMINLLKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILL 574
Query: 476 QEKNLRFVTTMVDILNTILLTSAELYELRALLKDRSKPWSRSLFLALHGCWCHSPVSLLA 535
+E++L+F +TMV LNTILLTS EL++LR LKD S++LF L+ WCH+PV+ ++
Sbjct: 575 REEDLKFASTMVHALNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVS 634
Query: 536 LCLLAHHYRHCNTLIATFGDLEITVEFLTEVDKLVQLIESPIFAYLRLELVG-EHSXXXX 594
LC L +YRH LI FGDLE+TV+FL EVDKLVQLIE PIF YLRL+L+ +++
Sbjct: 635 LCFLTQNYRHAYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLI 694
Query: 595 XXXXXXXXXXPQSDAFHALRARLHCLPPPHQPHRPRG-DEREGSEAADDEPLDYGALLAQ 653
PQS AF L RL C+P P S+ AD +DY LL
Sbjct: 695 KALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDSLKAAPKSQKADSPSIDYAELLQH 754
Query: 654 FHAVQAQHRQYR 665
F VQ +H + R
Sbjct: 755 FEKVQNKHLEVR 766
Score = 48.0 bits (109), Expect = 1e-04
Identities = 22/64 (34%), Positives = 38/64 (59%)
Query: 363 TKVAALDWILHLYNKLPKQMCGETERVWAGAVGSLTDAAHDVLRRALAVLAEICSAAGDL 422
T++A L W+ HLY K P++M T+ ++ + +L+D + +V+ + L VLAEI S+
Sbjct: 417 TRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVILKDLEVLAEIASSPAGQ 476
Query: 423 QSSP 426
P
Sbjct: 477 TDDP 480
>CR457343-1|CAG33624.1| 524|Homo sapiens FLJ10305 protein.
Length = 524
Score = 207 bits (505), Expect = 1e-52
Identities = 112/252 (44%), Positives = 149/252 (59%), Gaps = 3/252 (1%)
Query: 416 CSAAGDLQSSPYYYKFLQAXXXXXXXXXXXXXXXGAFIIRQLCVLLNAEDIYRALANILQ 475
CS + +S Y+YKF+ G FIIRQLC+LLNAE+I+ ++A+IL
Sbjct: 258 CSPSTPTMNS-YFYKFMINLLKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILL 316
Query: 476 QEKNLRFVTTMVDILNTILLTSAELYELRALLKDRSKPWSRSLFLALHGCWCHSPVSLLA 535
+E++L+F +TMV LNTILLTS EL++LR LKD S++LF L+ WCH+PV+ ++
Sbjct: 317 REEDLKFASTMVHALNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVS 376
Query: 536 LCLLAHHYRHCNTLIATFGDLEITVEFLTEVDKLVQLIESPIFAYLRLELVG-EHSXXXX 594
LC L +YRH LI FGDLE+TV+FL EVDKLVQLIE PIF YLRL+L+ +++
Sbjct: 377 LCFLTQNYRHAYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLI 436
Query: 595 XXXXXXXXXXPQSDAFHALRARLHCLPPPHQPHRPRG-DEREGSEAADDEPLDYGALLAQ 653
PQS AF L RL C+P P S+ AD +DY LL
Sbjct: 437 KALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDSLKAAPKSQKADSPSIDYAELLQH 496
Query: 654 FHAVQAQHRQYR 665
F VQ +H + R
Sbjct: 497 FEKVQNKHLEVR 508
Score = 85.8 bits (203), Expect = 4e-16
Identities = 42/76 (55%), Positives = 56/76 (73%), Gaps = 4/76 (5%)
Query: 246 MINILIIHAQSPEELLQLTAITWLKEFVELAGAAMLPFASGILCAVLPCHAYSDEPRKKR 305
M NIL+IH Q+ ++L+QLTA+ W++EF++LAG MLP++SGIL AVLPC AY D RKK
Sbjct: 1 MANILVIHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDD--RKK- 57
Query: 306 TGIRETAATVNFQLIK 321
I+E A N L+K
Sbjct: 58 -SIKEVANVCNQSLMK 72
Score = 48.0 bits (109), Expect = 1e-04
Identities = 22/64 (34%), Positives = 38/64 (59%)
Query: 363 TKVAALDWILHLYNKLPKQMCGETERVWAGAVGSLTDAAHDVLRRALAVLAEICSAAGDL 422
T++A L W+ HLY K P++M T+ ++ + +L+D + +V+ + L VLAEI S+
Sbjct: 159 TRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVILKDLEVLAEIASSPAGQ 218
Query: 423 QSSP 426
P
Sbjct: 219 TDDP 222
>BC007214-1|AAH07214.2| 575|Homo sapiens VAC14 protein protein.
Length = 575
Score = 207 bits (505), Expect = 1e-52
Identities = 112/252 (44%), Positives = 149/252 (59%), Gaps = 3/252 (1%)
Query: 416 CSAAGDLQSSPYYYKFLQAXXXXXXXXXXXXXXXGAFIIRQLCVLLNAEDIYRALANILQ 475
CS + +S Y+YKF+ G FIIRQLC+LLNAE+I+ ++A+IL
Sbjct: 309 CSPSTPTMNS-YFYKFMINLLKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILL 367
Query: 476 QEKNLRFVTTMVDILNTILLTSAELYELRALLKDRSKPWSRSLFLALHGCWCHSPVSLLA 535
+E++L+F +TMV LNTILLTS EL++LR LKD S++LF L+ WCH+PV+ ++
Sbjct: 368 REEDLKFASTMVHALNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVS 427
Query: 536 LCLLAHHYRHCNTLIATFGDLEITVEFLTEVDKLVQLIESPIFAYLRLELVG-EHSXXXX 594
LC L +YRH LI FGDLE+TV+FL EVDKLVQLIE PIF YLRL+L+ +++
Sbjct: 428 LCFLTQNYRHAYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLI 487
Query: 595 XXXXXXXXXXPQSDAFHALRARLHCLPPPHQPHRPRG-DEREGSEAADDEPLDYGALLAQ 653
PQS AF L RL C+P P S+ AD +DY LL
Sbjct: 488 KALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDSLKAAPKSQKADSPSIDYAELLQH 547
Query: 654 FHAVQAQHRQYR 665
F VQ +H + R
Sbjct: 548 FEKVQNKHLEVR 559
Score = 144 bits (349), Expect = 9e-34
Identities = 69/127 (54%), Positives = 94/127 (74%), Gaps = 4/127 (3%)
Query: 195 LNVLAHLPDLLDGLFKMLDDPNPEIRRMCDVQLNEFLRSIKKEPAKVDFQAMINILIIHA 254
+N+L +LP++LDGLF++L D EIR+MC+V L EFL+ IKK P+ V F M NIL+IH
Sbjct: 1 INLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILVIHC 60
Query: 255 QSPEELLQLTAITWLKEFVELAGAAMLPFASGILCAVLPCHAYSDEPRKKRTGIRETAAT 314
Q+ ++L+QLTA+ W++EF++LAG MLP++SGIL AVLPC AY D RKK I+E A
Sbjct: 61 QTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDD--RKK--SIKEVANV 116
Query: 315 VNFQLIK 321
N L+K
Sbjct: 117 CNQSLMK 123
Score = 48.0 bits (109), Expect = 1e-04
Identities = 22/64 (34%), Positives = 38/64 (59%)
Query: 363 TKVAALDWILHLYNKLPKQMCGETERVWAGAVGSLTDAAHDVLRRALAVLAEICSAAGDL 422
T++A L W+ HLY K P++M T+ ++ + +L+D + +V+ + L VLAEI S+
Sbjct: 210 TRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVILKDLEVLAEIASSPAGQ 269
Query: 423 QSSP 426
P
Sbjct: 270 TDDP 273
>BC000536-1|AAH00536.2| 356|Homo sapiens VAC14 protein protein.
Length = 356
Score = 207 bits (505), Expect = 1e-52
Identities = 112/252 (44%), Positives = 149/252 (59%), Gaps = 3/252 (1%)
Query: 416 CSAAGDLQSSPYYYKFLQAXXXXXXXXXXXXXXXGAFIIRQLCVLLNAEDIYRALANILQ 475
CS + +S Y+YKF+ G FIIRQLC+LLNAE+I+ ++A+IL
Sbjct: 90 CSPSTPTMNS-YFYKFMINLLKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILL 148
Query: 476 QEKNLRFVTTMVDILNTILLTSAELYELRALLKDRSKPWSRSLFLALHGCWCHSPVSLLA 535
+E++L+F +TMV LNTILLTS EL++LR LKD S++LF L+ WCH+PV+ ++
Sbjct: 149 REEDLKFASTMVHALNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVS 208
Query: 536 LCLLAHHYRHCNTLIATFGDLEITVEFLTEVDKLVQLIESPIFAYLRLELVG-EHSXXXX 594
LC L +YRH LI FGDLE+TV+FL EVDKLVQLIE PIF YLRL+L+ +++
Sbjct: 209 LCFLTQNYRHAYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLI 268
Query: 595 XXXXXXXXXXPQSDAFHALRARLHCLPPPHQPHRPRG-DEREGSEAADDEPLDYGALLAQ 653
PQS AF L RL C+P P S+ AD +DY LL
Sbjct: 269 KALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDSLKAAPKSQKADSPSIDYAELLQH 328
Query: 654 FHAVQAQHRQYR 665
F VQ +H + R
Sbjct: 329 FEKVQNKHLEVR 340
Score = 36.3 bits (80), Expect = 0.36
Identities = 18/54 (33%), Positives = 31/54 (57%)
Query: 373 HLYNKLPKQMCGETERVWAGAVGSLTDAAHDVLRRALAVLAEICSAAGDLQSSP 426
HLY K P++M T+ ++ + +L+D + +V+ + L VLAEI S+ P
Sbjct: 1 HLYIKTPRKMFRHTDSLFPILLQTLSDESDEVILKDLEVLAEIASSPAGQTDDP 54
>AK025479-1|BAB15145.1| 524|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21826 fis, clone HEP01350. ).
Length = 524
Score = 207 bits (505), Expect = 1e-52
Identities = 112/252 (44%), Positives = 149/252 (59%), Gaps = 3/252 (1%)
Query: 416 CSAAGDLQSSPYYYKFLQAXXXXXXXXXXXXXXXGAFIIRQLCVLLNAEDIYRALANILQ 475
CS + +S Y+YKF+ G FIIRQLC+LLNAE+I+ ++A+IL
Sbjct: 258 CSPSTPTMNS-YFYKFMINLLKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILL 316
Query: 476 QEKNLRFVTTMVDILNTILLTSAELYELRALLKDRSKPWSRSLFLALHGCWCHSPVSLLA 535
+E++L+F +TMV LNTILLTS EL++LR LKD S++LF L+ WCH+PV+ ++
Sbjct: 317 REEDLKFASTMVHALNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVS 376
Query: 536 LCLLAHHYRHCNTLIATFGDLEITVEFLTEVDKLVQLIESPIFAYLRLELVG-EHSXXXX 594
LC L +YRH LI FGDLE+TV+FL EVDKLVQLIE PIF YLRL+L+ +++
Sbjct: 377 LCFLTQNYRHAYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLI 436
Query: 595 XXXXXXXXXXPQSDAFHALRARLHCLPPPHQPHRPRG-DEREGSEAADDEPLDYGALLAQ 653
PQS AF L RL C+P P S+ AD +DY LL
Sbjct: 437 KALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDSLKAAPKSQKADSPSIDYAELLQH 496
Query: 654 FHAVQAQHRQYR 665
F VQ +H + R
Sbjct: 497 FEKVQNKHLEVR 508
Score = 85.8 bits (203), Expect = 4e-16
Identities = 42/76 (55%), Positives = 56/76 (73%), Gaps = 4/76 (5%)
Query: 246 MINILIIHAQSPEELLQLTAITWLKEFVELAGAAMLPFASGILCAVLPCHAYSDEPRKKR 305
M NIL+IH Q+ ++L+QLTA+ W++EF++LAG MLP++SGIL AVLPC AY D RKK
Sbjct: 1 MANILVIHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDD--RKK- 57
Query: 306 TGIRETAATVNFQLIK 321
I+E A N L+K
Sbjct: 58 -SIKEVANVCNQSLMK 72
Score = 48.0 bits (109), Expect = 1e-04
Identities = 22/64 (34%), Positives = 38/64 (59%)
Query: 363 TKVAALDWILHLYNKLPKQMCGETERVWAGAVGSLTDAAHDVLRRALAVLAEICSAAGDL 422
T++A L W+ HLY K P++M T+ ++ + +L+D + +V+ + L VLAEI S+
Sbjct: 159 TRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVILKDLEVLAEIASSPAGQ 218
Query: 423 QSSP 426
P
Sbjct: 219 TDDP 222
>AK001167-1|BAA91530.1| 347|Homo sapiens protein ( Homo sapiens
cDNA FLJ10305 fis, clone NT2RM2000239. ).
Length = 347
Score = 206 bits (504), Expect = 2e-52
Identities = 112/252 (44%), Positives = 149/252 (59%), Gaps = 3/252 (1%)
Query: 416 CSAAGDLQSSPYYYKFLQAXXXXXXXXXXXXXXXGAFIIRQLCVLLNAEDIYRALANILQ 475
CS + +S Y+YKF+ G FIIRQLC+LLNAE+I+ ++A+IL
Sbjct: 81 CSPSTPTMNS-YFYKFMINLLKRFSSEWKLLEVRGPFIIRQLCLLLNAENIFHSMADILL 139
Query: 476 QEKNLRFVTTMVDILNTILLTSAELYELRALLKDRSKPWSRSLFLALHGCWCHSPVSLLA 535
+E++L+F +TMV LNTILLTS EL++LR LKD S++LF L+ WCH+PV+ ++
Sbjct: 140 REEDLKFASTMVHALNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVS 199
Query: 536 LCLLAHHYRHCNTLIATFGDLEITVEFLTEVDKLVQLIESPIFAYLRLELVG-EHSXXXX 594
LC L +YRH LI FGDLE+TV+FL EVDKLVQLIE PIF YLRL+L+ +++
Sbjct: 200 LCFLTQNYRHAYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLI 259
Query: 595 XXXXXXXXXXPQSDAFHALRARLHCLPPPHQPHRPRG-DEREGSEAADDEPLDYGALLAQ 653
PQS AF L RL C+P P S+ AD +DY LL
Sbjct: 260 KALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDSLKAAPKSQKADSPSIDYAELLQH 319
Query: 654 FHAVQAQHRQYR 665
F VQ +H + R
Sbjct: 320 FEKVQNKHLEVR 331
>U25801-1|AAB03813.1| 167|Homo sapiens Tax1 binding protein
protein.
Length = 167
Score = 97.1 bits (231), Expect = 2e-19
Identities = 48/91 (52%), Positives = 64/91 (70%), Gaps = 4/91 (4%)
Query: 231 LRSIKKEPAKVDFQAMINILIIHAQSPEELLQLTAITWLKEFVELAGAAMLPFASGILCA 290
L+ IKK P+ V F M NI +IH Q+ ++L+QLTA+ W++EF++LAG MLP++SGIL A
Sbjct: 1 LKEIKKNPSSVKFPEMANIPVIHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTA 60
Query: 291 VLPCHAYSDEPRKKRTGIRETAATVNFQLIK 321
VLPC AY D RKK I+E A N L+K
Sbjct: 61 VLPCLAYDD--RKK--SIKEVANVCNQSLMK 87
>AF054284-1|AAC97189.1| 1304|Homo sapiens spliceosomal protein SAP
155 protein.
Length = 1304
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/110 (22%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Query: 14 VRGLCDKLYEKRKVAGVEIEKMVKDFNDAKNTSQIKKLIKVLGQDLMSSTNPNMKNGALM 73
V L D+ + RK+ IEK++ + A ++++ +++ L + ++ ++
Sbjct: 854 VDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEE--QLIDGILYAFQEQTTEDSVML 911
Query: 74 -GLSTVAVGLGKASVDYLPELTNPIVACFSESESRVRYQAAEALFNFPVI 122
G TV LGK YLP++ ++ + ++VR QAA+ + V+
Sbjct: 912 NGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAVV 961
>BC072420-1|AAH72420.1| 887|Homo sapiens transportin 2 (importin 3,
karyopherin beta 2b) protein.
Length = 887
Score = 33.5 bits (73), Expect = 2.5
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 67 MKNGALMGLSTVAVGLGKASVDYLPELTNPIVACFSESESRVRYQAAEALFNFPVIFDAL 126
+K ++ L +A G + V YLPEL ++ C S+ ++ VR A L + A
Sbjct: 410 VKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRY-----AH 464
Query: 127 AKLAADPEQQVKH-AAELLDRLL 148
++ P+ +K ELL R+L
Sbjct: 465 WVVSQPPDMHLKPLMTELLKRIL 487
>BC018314-1|AAH18314.1| 771|Homo sapiens Unknown (protein for
IMAGE:4154236) protein.
Length = 771
Score = 33.5 bits (73), Expect = 2.5
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 67 MKNGALMGLSTVAVGLGKASVDYLPELTNPIVACFSESESRVRYQAAEALFNFPVIFDAL 126
+K ++ L +A G + V YLPEL ++ C S+ ++ VR A L + A
Sbjct: 410 VKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRY-----AH 464
Query: 127 AKLAADPEQQVKH-AAELLDRLL 148
++ P+ +K ELL R+L
Sbjct: 465 WVVSQPPDMHLKPLMTELLKRIL 487
>AF019039-1|AAB83973.1| 896|Homo sapiens transportin2 protein.
Length = 896
Score = 33.5 bits (73), Expect = 2.5
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 67 MKNGALMGLSTVAVGLGKASVDYLPELTNPIVACFSESESRVRYQAAEALFNFPVIFDAL 126
+K ++ L +A G + V YLPEL ++ C S+ ++ VR A L + A
Sbjct: 409 VKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRY-----AH 463
Query: 127 AKLAADPEQQVKH-AAELLDRLL 148
++ P+ +K ELL R+L
Sbjct: 464 WVVSQPPDMHLKPLMTELLKRIL 486
>AF007748-1|AAB71349.1| 887|Homo sapiens karyopherin beta2b homolog
protein.
Length = 887
Score = 33.5 bits (73), Expect = 2.5
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 67 MKNGALMGLSTVAVGLGKASVDYLPELTNPIVACFSESESRVRYQAAEALFNFPVIFDAL 126
+K ++ L +A G + V YLPEL ++ C S+ ++ VR A L + A
Sbjct: 410 VKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRY-----AH 464
Query: 127 AKLAADPEQQVKH-AAELLDRLL 148
++ P+ +K ELL R+L
Sbjct: 465 WVVSQPPDMHLKPLMTELLKRIL 487
>AB210011-1|BAE06093.1| 1051|Homo sapiens TNPO2 variant protein
protein.
Length = 1051
Score = 33.5 bits (73), Expect = 2.5
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 67 MKNGALMGLSTVAVGLGKASVDYLPELTNPIVACFSESESRVRYQAAEALFNFPVIFDAL 126
+K ++ L +A G + V YLPEL ++ C S+ ++ VR A L + A
Sbjct: 574 VKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRY-----AH 628
Query: 127 AKLAADPEQQVKH-AAELLDRLL 148
++ P+ +K ELL R+L
Sbjct: 629 WVVSQPPDMHLKPLMTELLKRIL 651
>U72395-1|AAB68948.1| 890|Homo sapiens MIP protein.
Length = 890
Score = 32.3 bits (70), Expect = 5.8
Identities = 13/43 (30%), Positives = 24/43 (55%)
Query: 67 MKNGALMGLSTVAVGLGKASVDYLPELTNPIVACFSESESRVR 109
+K ++ L +A G + + YLPEL ++ C S+ ++ VR
Sbjct: 413 VKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVR 455
>U72069-1|AAB58254.1| 890|Homo sapiens karyopherin beta2 protein.
Length = 890
Score = 32.3 bits (70), Expect = 5.8
Identities = 13/43 (30%), Positives = 24/43 (55%)
Query: 67 MKNGALMGLSTVAVGLGKASVDYLPELTNPIVACFSESESRVR 109
+K ++ L +A G + + YLPEL ++ C S+ ++ VR
Sbjct: 413 VKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVR 455
>U70322-1|AAC50723.1| 890|Homo sapiens transportin protein.
Length = 890
Score = 32.3 bits (70), Expect = 5.8
Identities = 13/43 (30%), Positives = 24/43 (55%)
Query: 67 MKNGALMGLSTVAVGLGKASVDYLPELTNPIVACFSESESRVR 109
+K ++ L +A G + + YLPEL ++ C S+ ++ VR
Sbjct: 413 VKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVR 455
>BC047240-1|AAH47240.1| 855|Homo sapiens HEAT repeat containing 2
protein.
Length = 855
Score = 32.3 bits (70), Expect = 5.8
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 208 LFKMLDDPNPEIRRMCDVQLNEFLRSIKKEPAKVDFQAMINIL----IIHAQSPEELLQL 263
L K LDD + ++R L +L+ +K AK +Q+ + L ++H PE +Q
Sbjct: 748 LLKRLDDVSNDVRMAAASTLVTWLQCVKGANAKSYYQSSVQYLYRELLVHLDDPERAIQD 807
Query: 264 TAITWLKE 271
+ LKE
Sbjct: 808 AILEVLKE 815
>BC040340-1|AAH40340.1| 890|Homo sapiens transportin 1 protein.
Length = 890
Score = 32.3 bits (70), Expect = 5.8
Identities = 13/43 (30%), Positives = 24/43 (55%)
Query: 67 MKNGALMGLSTVAVGLGKASVDYLPELTNPIVACFSESESRVR 109
+K ++ L +A G + + YLPEL ++ C S+ ++ VR
Sbjct: 413 VKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVR 455
>AK000404-1|BAA91142.1| 235|Homo sapiens protein ( Homo sapiens
cDNA FLJ20397 fis, clone KAT00565. ).
Length = 235
Score = 32.3 bits (70), Expect = 5.8
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 208 LFKMLDDPNPEIRRMCDVQLNEFLRSIKKEPAKVDFQAMINIL----IIHAQSPEELLQL 263
L K LDD + ++R L +L+ +K AK +Q+ + L ++H PE +Q
Sbjct: 128 LLKRLDDVSNDVRMAAASTLVTWLQCVKGANAKSYYQSSVQYLYRELLVHLDDPERAIQD 187
Query: 264 TAITWLKE 271
+ LKE
Sbjct: 188 AILEVLKE 195
>U77700-1|AAC51648.1| 1928|Homo sapiens HsGCN1 protein.
Length = 1928
Score = 31.9 bits (69), Expect = 7.7
Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 4/94 (4%)
Query: 23 EKRKVAGVEIEKMVKDFNDAKNTSQIKKLIKVLGQDLMSSTNPNMKNGALMGLSTVAVGL 82
E K G+ I D S LI++LG D S N+K L LS + +
Sbjct: 1441 EAAKALGLVIRLTSADVLRPSVVSITGPLIRILG-DRFSW---NVKAALLETLSLLLAKV 1496
Query: 83 GKASVDYLPELTNPIVACFSESESRVRYQAAEAL 116
G A +LP+L +S VR +AA+AL
Sbjct: 1497 GIALKPFLPQLQTTFTKALQDSNRGVRLKAADAL 1530
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.136 0.403
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 83,958,271
Number of Sequences: 224733
Number of extensions: 3060060
Number of successful extensions: 6459
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 6402
Number of HSP's gapped (non-prelim): 49
length of query: 680
length of database: 73,234,838
effective HSP length: 95
effective length of query: 585
effective length of database: 51,885,203
effective search space: 30352843755
effective search space used: 30352843755
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 69 (31.9 bits)
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