Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000180-TA|BGIBMGA000180-PA|IPR002372|Pyrrolo-quinoline
quinone, IPR000719|Protein kinase, IPR010513|Ribonuclease 2-5A,
IPR011009|Protein kinase-like, IPR011047|Quinonprotein alcohol
dehydrogenase-like, IPR008271|Serine/threonine protein kinase, active
site, IPR002290|Serine/threonine protein kinase, IPR006567|PUG
(973 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC130407-1|AAI30408.1| 977|Homo sapiens endoplasmic reticulum t... 464 e-130
BC130405-1|AAI30406.1| 977|Homo sapiens endoplasmic reticulum t... 464 e-130
AB209869-1|BAD93106.1| 1006|Homo sapiens endoplasmic reticulum t... 464 e-130
AF059198-1|AAC25991.1| 977|Homo sapiens protein kinase/endoribo... 463 e-129
AK131280-1|BAD18455.1| 974|Homo sapiens protein ( Homo sapiens ... 400 e-111
AB047079-1|BAB21297.1| 925|Homo sapiens protein kinase/ribonucl... 398 e-110
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 93 3e-18
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 93 3e-18
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 93 3e-18
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 93 3e-18
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 93 3e-18
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 92 1e-17
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 92 1e-17
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 92 1e-17
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 92 1e-17
L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-depend... 90 4e-17
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 89 9e-17
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 89 9e-17
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 89 9e-17
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 89 9e-17
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 89 9e-17
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 89 9e-17
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 89 9e-17
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 89 9e-17
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 88 2e-16
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 88 2e-16
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 88 2e-16
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 88 2e-16
BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein. 88 2e-16
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 88 2e-16
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 88 2e-16
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 88 2e-16
AL713896-5|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 88 2e-16
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 88 2e-16
AL713896-3|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 88 2e-16
AL713896-2|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 88 2e-16
AL713896-1|CAI13787.1| 453|Homo sapiens calcium/calmodulin-depe... 88 2e-16
AL596247-5|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 88 2e-16
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 88 2e-16
AL596247-3|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 88 2e-16
AL596247-2|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 88 2e-16
AL596247-1|CAI13964.1| 453|Homo sapiens calcium/calmodulin-depe... 88 2e-16
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 88 2e-16
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 88 2e-16
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 88 2e-16
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 87 2e-16
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 87 2e-16
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 87 2e-16
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 87 2e-16
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 87 2e-16
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 87 2e-16
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 87 3e-16
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 87 3e-16
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 87 3e-16
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 87 3e-16
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 87 3e-16
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 87 3e-16
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 87 3e-16
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 87 3e-16
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 87 3e-16
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 87 3e-16
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 87 3e-16
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 87 3e-16
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 87 4e-16
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 86 7e-16
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 86 7e-16
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 85 1e-15
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 85 1e-15
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 85 1e-15
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 85 1e-15
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 85 1e-15
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 85 1e-15
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 85 1e-15
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 83 5e-15
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 83 5e-15
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 83 5e-15
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 83 5e-15
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 83 5e-15
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 83 5e-15
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 83 5e-15
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 82 8e-15
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 81 1e-14
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 81 1e-14
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 81 1e-14
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 81 1e-14
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 81 1e-14
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 81 1e-14
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 81 1e-14
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 81 1e-14
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 81 1e-14
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 81 1e-14
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 81 1e-14
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 81 1e-14
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 81 1e-14
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 81 2e-14
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 81 2e-14
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 81 2e-14
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 81 2e-14
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 81 2e-14
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 81 2e-14
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 81 2e-14
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 81 2e-14
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 81 2e-14
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 81 2e-14
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 81 2e-14
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 81 2e-14
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 80 3e-14
CR542225-1|CAG47021.1| 372|Homo sapiens STK17B protein. 80 4e-14
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 80 4e-14
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 80 4e-14
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 79 6e-14
BC016040-1|AAH16040.1| 372|Homo sapiens serine/threonine kinase... 79 6e-14
AC114760-2|AAY14982.1| 372|Homo sapiens unknown protein. 79 6e-14
AB011421-1|BAA34127.1| 372|Homo sapiens DRAK2 protein. 79 6e-14
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 79 8e-14
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 79 8e-14
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 79 8e-14
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 79 8e-14
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 79 1e-13
BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase... 79 1e-13
BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase... 79 1e-13
AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein. 79 1e-13
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 78 1e-13
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 78 1e-13
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 78 1e-13
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 78 1e-13
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 78 2e-13
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 78 2e-13
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 78 2e-13
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 78 2e-13
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 78 2e-13
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 78 2e-13
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 78 2e-13
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 78 2e-13
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 78 2e-13
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 78 2e-13
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 78 2e-13
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 78 2e-13
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 78 2e-13
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 77 2e-13
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 77 2e-13
U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein ... 77 2e-13
U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein. 77 2e-13
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 77 2e-13
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 77 2e-13
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 77 2e-13
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 77 2e-13
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 77 2e-13
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 77 2e-13
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 77 2e-13
BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase... 77 2e-13
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 77 2e-13
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 77 2e-13
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 77 2e-13
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 77 3e-13
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 77 3e-13
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 77 3e-13
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 77 3e-13
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 77 4e-13
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 77 4e-13
CR542210-1|CAG47006.1| 372|Homo sapiens STK17B protein. 77 4e-13
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 77 4e-13
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 77 4e-13
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 77 4e-13
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 77 4e-13
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 77 4e-13
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 77 4e-13
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 77 4e-13
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 77 4e-13
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 76 5e-13
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 76 7e-13
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 76 7e-13
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 75 9e-13
BC064422-1|AAH64422.1| 241|Homo sapiens PNCK protein protein. 75 9e-13
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 75 9e-13
AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein. 75 9e-13
AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase... 75 9e-13
BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein. 75 2e-12
BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein. 75 2e-12
BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein. 75 2e-12
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 75 2e-12
AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein. 75 2e-12
AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein. 75 2e-12
AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein. 75 2e-12
AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein. 75 2e-12
AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein. 75 2e-12
AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein. 75 2e-12
AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein. 75 2e-12
AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing ... 75 2e-12
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 74 2e-12
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 74 2e-12
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 74 2e-12
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 74 2e-12
U63973-1|AAB05929.1| 563|Homo sapiens rhodopsin kinase protein. 74 3e-12
L77503-1|AAG50439.1| 563|Homo sapiens rhodopsin kinase protein. 74 3e-12
L77502-1|AAT00534.2| 563|Homo sapiens rhodopsin kinase protein. 74 3e-12
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 74 3e-12
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 74 3e-12
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 74 3e-12
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 74 3e-12
U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein ... 73 4e-12
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 73 4e-12
BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein. 73 4e-12
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 73 4e-12
AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens ... 73 4e-12
AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase p... 73 4e-12
AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein. 73 4e-12
AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b v... 73 4e-12
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 73 4e-12
X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein ... 73 5e-12
AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase... 73 5e-12
AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase... 73 5e-12
AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase... 73 5e-12
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 73 5e-12
BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H... 73 7e-12
BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H... 73 7e-12
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 73 7e-12
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 73 7e-12
AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase... 73 7e-12
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 73 7e-12
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 73 7e-12
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 73 7e-12
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 72 9e-12
U50648-1|AAC50768.1| 551|Homo sapiens interferon-inducible RNA-... 72 9e-12
M85294-1|AAA18253.1| 551|Homo sapiens P1/eIF-2a protein kinase ... 72 9e-12
M35663-1|AAA36409.1| 551|Homo sapiens protein ( Human p68 kinas... 72 9e-12
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 72 9e-12
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 72 9e-12
BC101475-1|AAI01476.1| 551|Homo sapiens eukaryotic translation ... 72 9e-12
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 72 9e-12
BC093676-1|AAH93676.1| 551|Homo sapiens eukaryotic translation ... 72 9e-12
BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase, g... 72 9e-12
BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase, g... 72 9e-12
BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase, g... 72 9e-12
BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase, g... 72 9e-12
BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase, g... 72 9e-12
BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein. 72 9e-12
AY302136-1|AAP57628.1| 510|Homo sapiens interferon-inducible do... 72 9e-12
AY228338-1|AAO38055.1| 551|Homo sapiens protein kinase, interfe... 72 9e-12
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 72 9e-12
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 72 9e-12
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 72 9e-12
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 72 9e-12
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 72 9e-12
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 72 9e-12
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 72 9e-12
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 72 9e-12
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 72 9e-12
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 72 9e-12
AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase ga... 72 9e-12
AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b p... 72 9e-12
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 72 9e-12
AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein. 72 9e-12
AC007899-1|AAY24317.1| 551|Homo sapiens unknown protein. 72 9e-12
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 72 9e-12
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 72 1e-11
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 72 1e-11
U63721-3|AAC13886.1| 633|Homo sapiens LIM-kinase protein. 72 1e-11
U63721-2|AAC13885.1| 647|Homo sapiens LIM-kinase protein. 72 1e-11
U62293-2|AAB17546.1| 633|Homo sapiens alternatively spliced LIM... 72 1e-11
U62293-1|AAB17545.1| 647|Homo sapiens LIM-kinase1 protein. 72 1e-11
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 72 1e-11
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 72 1e-11
D26309-1|BAA05371.1| 647|Homo sapiens LIM kinase protein. 72 1e-11
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 72 1e-11
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 72 1e-11
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 72 1e-11
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 72 1e-11
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 72 1e-11
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 72 1e-11
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 72 1e-11
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 72 1e-11
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 72 1e-11
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 72 1e-11
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 72 1e-11
AF111105-1|AAD28547.1| 618|Homo sapiens mitogen-activated prote... 72 1e-11
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 72 1e-11
AC005057-3|AAS07438.1| 596|Homo sapiens unknown protein. 72 1e-11
BC126356-1|AAI26357.1| 1115|Homo sapiens eukaryotic translation ... 71 2e-11
BC126354-1|AAI26355.1| 1116|Homo sapiens eukaryotic translation ... 71 2e-11
AF284615-1|AAF91480.1| 1115|Homo sapiens initiation factor 2-alp... 71 2e-11
AF193339-1|AAF61199.1| 1115|Homo sapiens eukaryotic translation ... 71 2e-11
AF110146-1|AAD19961.1| 1115|Homo sapiens eukaryotic translation ... 71 2e-11
AC104134-2|AAY24331.1| 970|Homo sapiens unknown protein. 71 2e-11
U56816-1|AAC50949.1| 499|Homo sapiens kinase Myt1 protein. 71 2e-11
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 71 2e-11
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 71 2e-11
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 71 2e-11
BC130011-1|AAI30012.1| 485|Homo sapiens PKMYT1 protein protein. 71 2e-11
BC121162-1|AAI21163.1| 485|Homo sapiens PKMYT1 protein protein. 71 2e-11
BC121161-1|AAI21162.1| 485|Homo sapiens PKMYT1 protein protein. 71 2e-11
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 71 2e-11
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 71 2e-11
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 71 2e-11
AK055778-1|BAB71011.1| 1113|Homo sapiens protein ( Homo sapiens ... 71 2e-11
AF549406-1|AAN40703.1| 499|Homo sapiens membrane-associated tyr... 71 2e-11
AF391558-1|AAO13803.1| 1192|Homo sapiens myosin IIIB variant MYO... 71 2e-11
AF391557-1|AAO13802.1| 1275|Homo sapiens myosin IIIB variant MYO... 71 2e-11
AF391556-1|AAO13801.1| 1314|Homo sapiens myosin IIIB variant MYO... 71 2e-11
AF391555-1|AAO13800.1| 1341|Homo sapiens myosin IIIB variant MYO... 71 2e-11
AF391554-1|AAO13799.1| 1251|Homo sapiens myosin IIIB variant MYO... 71 2e-11
AF369908-1|AAL57233.1| 1278|Homo sapiens myosin IIIB protein. 71 2e-11
AF014118-1|AAB71843.1| 499|Homo sapiens membrane-associated kin... 71 2e-11
AC114794-1|AAY24159.1| 249|Homo sapiens unknown protein. 71 2e-11
AC004235-1|AAC04477.1| 495|Homo sapiens Myt1 protein. 71 2e-11
AC004233-1|AAC04478.1| 499|Homo sapiens Myt1 protein. 71 2e-11
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 71 3e-11
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 71 3e-11
BC034673-1|AAH34673.1| 1332|Homo sapiens misshapen-like kinase 1... 71 3e-11
AY775058-1|AAV41830.1| 1312|Homo sapiens misshapen/NIKs-related ... 71 3e-11
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 71 3e-11
AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein. 71 3e-11
AB209179-1|BAD92416.1| 546|Homo sapiens polo-like kinase varian... 71 3e-11
AB083211-1|BAC43747.1| 312|Homo sapiens truncated ZAP kinase pr... 71 3e-11
AB041926-1|BAA94838.1| 1303|Homo sapiens GCK family kinase MINK-... 71 3e-11
AB035698-1|BAA90753.1| 1295|Homo sapiens Misshapen/NIK-related k... 71 3e-11
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 70 4e-11
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 70 4e-11
U12779-1|AAA20851.1| 370|Homo sapiens MAP kinase activated prot... 70 4e-11
BC052584-1|AAH52584.1| 400|Homo sapiens mitogen-activated prote... 70 4e-11
BC036060-1|AAH36060.2| 400|Homo sapiens mitogen-activated prote... 70 4e-11
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 70 4e-11
AL591846-12|CAI13544.1| 400|Homo sapiens mitogen-activated prot... 70 4e-11
AL591846-11|CAI13543.1| 370|Homo sapiens mitogen-activated prot... 70 4e-11
AL358612-2|CAH73815.1| 197|Homo sapiens myosin IIIA protein. 70 4e-11
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 70 4e-11
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 70 4e-11
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 70 5e-11
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 70 5e-11
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 70 5e-11
BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein. 70 5e-11
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 70 5e-11
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 70 5e-11
AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens ... 70 5e-11
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 70 5e-11
AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S... 70 5e-11
AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L... 70 5e-11
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 70 5e-11
U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein. 69 6e-11
BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein. 69 6e-11
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 69 8e-11
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 69 8e-11
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 69 8e-11
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 69 8e-11
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 69 8e-11
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 69 8e-11
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 69 8e-11
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 69 8e-11
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 69 8e-11
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 69 8e-11
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 69 8e-11
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 69 8e-11
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 69 8e-11
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 69 8e-11
AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens ... 69 8e-11
AK000556-1|BAA91251.1| 293|Homo sapiens protein ( Homo sapiens ... 69 8e-11
AF167472-1|AAF13156.1| 551|Homo sapiens double stranded RNA act... 69 8e-11
BC065755-1|AAH65755.1| 234|Homo sapiens MAP3K2 protein protein. 69 1e-10
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 69 1e-10
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 68 1e-10
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 68 1e-10
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 68 1e-10
L40027-1|AAA62432.1| 483|Homo sapiens glycogen synthase kinase ... 68 1e-10
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 68 1e-10
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 68 1e-10
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 68 1e-10
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 68 1e-10
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 68 1e-10
D63424-1|BAA23608.1| 483|Homo sapiens glycogen synthase kinase ... 68 1e-10
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 68 1e-10
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 68 1e-10
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 68 1e-10
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 68 1e-10
BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein. 68 1e-10
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 68 1e-10
BC051865-1|AAH51865.1| 483|Homo sapiens glycogen synthase kinas... 68 1e-10
BC027984-1|AAH27984.1| 483|Homo sapiens glycogen synthase kinas... 68 1e-10
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 68 1e-10
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 68 1e-10
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 68 1e-10
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 68 1e-10
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 68 1e-10
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 68 1e-10
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 68 1e-10
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 68 1e-10
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 68 1e-10
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 68 1e-10
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 68 1e-10
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 68 1e-10
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 68 1e-10
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 68 1e-10
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 68 1e-10
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 68 1e-10
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 68 1e-10
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 68 1e-10
AC006486-1|AAD11986.1| 483|Homo sapiens KG3A_HUMAN protein. 68 1e-10
Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase p... 68 2e-10
X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase pr... 68 2e-10
L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase p... 68 2e-10
BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein. 68 2e-10
BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein. 68 2e-10
BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase ... 68 2e-10
BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase ... 68 2e-10
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 68 2e-10
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 68 2e-10
AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase ... 68 2e-10
AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase ... 68 2e-10
AL117326-3|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 68 2e-10
AL117326-2|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 68 2e-10
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 68 2e-10
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 68 2e-10
AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein. 68 2e-10
AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein. 68 2e-10
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 68 2e-10
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 68 2e-10
AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase ... 68 2e-10
AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein. 68 2e-10
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 68 2e-10
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 68 2e-10
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 68 2e-10
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 67 2e-10
U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor ... 67 2e-10
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 67 2e-10
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 67 2e-10
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 67 2e-10
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 67 2e-10
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 67 2e-10
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 67 2e-10
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 67 2e-10
M14504-1|AAA36519.1| 150|Homo sapiens protein ( Human protein-s... 67 2e-10
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 67 2e-10
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 67 2e-10
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 67 2e-10
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 67 2e-10
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 67 2e-10
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 67 2e-10
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 67 2e-10
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 67 2e-10
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 67 2e-10
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 67 2e-10
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 67 2e-10
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 67 2e-10
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 67 2e-10
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 67 2e-10
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 67 2e-10
AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinas... 67 2e-10
AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinas... 67 2e-10
AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinas... 67 2e-10
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 67 2e-10
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 67 2e-10
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 67 2e-10
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 67 2e-10
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 67 2e-10
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 67 2e-10
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 67 2e-10
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 67 3e-10
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 67 3e-10
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 67 3e-10
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 67 3e-10
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 67 3e-10
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 67 3e-10
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 67 3e-10
BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein. 67 3e-10
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 67 3e-10
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 67 3e-10
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 67 3e-10
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 67 3e-10
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 67 3e-10
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 67 3e-10
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 67 3e-10
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 67 3e-10
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 67 3e-10
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 66 4e-10
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 66 4e-10
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 66 4e-10
U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein. 66 4e-10
U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta... 66 4e-10
U00686-1|AAA03565.1| 544|Homo sapiens putative novel receptor k... 66 4e-10
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 66 4e-10
L16862-1|AAA60175.1| 576|Homo sapiens G protein-coupled recepto... 66 4e-10
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 66 4e-10
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 66 4e-10
BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated prote... 66 4e-10
BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein. 66 4e-10
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 66 4e-10
BC009277-1|AAH09277.1| 576|Homo sapiens G protein-coupled recep... 66 4e-10
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 66 4e-10
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 66 4e-10
AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein. 66 4e-10
AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein k... 66 4e-10
AF125532-1|AAF17226.1| 414|Homo sapiens map kinase-interacting ... 66 4e-10
AF040752-1|AAC09274.1| 560|Homo sapiens G protein-coupled recep... 66 4e-10
AF040751-1|AAC09273.1| 589|Homo sapiens G protein-coupled recep... 66 4e-10
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 66 4e-10
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 66 6e-10
>BC130407-1|AAI30408.1| 977|Homo sapiens endoplasmic reticulum to
nucleus signalling 1 protein.
Length = 977
Score = 464 bits (1143), Expect = e-130
Identities = 224/399 (56%), Positives = 289/399 (72%), Gaps = 7/399 (1%)
Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535
+GKI+F VLG G EGT VYRG FD RDVAVKR+LPECF+FADREV LLRESD H +V
Sbjct: 566 VGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNV 625
Query: 536 VRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIV 595
+RY+CTE+D+QF+YIA+ELC+ATLQ+YVE+K ++ + +L+Q T GL+HLHS++IV
Sbjct: 626 IRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIV 685
Query: 596 HRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN- 654
HRD+KPHN+L+SMP+ G+++AMISDFGL KKL +GR SFSRRSGV GT+GWIAPEM++
Sbjct: 686 HRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSE 745
Query: 655 --GERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEE-EL 711
E T ++DIFS GCVFYYV+S+G HPFG L+RQANIL G +LD L PE+ E
Sbjct: 746 DCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLH---PEKHED 802
Query: 712 VVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPL 771
V+ + LI MI+ P RP + +LK+P FW + L F QDVSD++E + L
Sbjct: 803 VIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQL 862
Query: 772 ERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSL 831
ERGG V++ DWR + + DLR RTY+G V LLRA+RNKKHHYREL ++VR++L
Sbjct: 863 ERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETL 922
Query: 832 GKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYY 870
G LPD FV Y+ +RFP LL H + M+ E + Q YY
Sbjct: 923 GSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYY 961
Score = 188 bits (458), Expect = 8e-47
Identities = 119/338 (35%), Positives = 184/338 (54%), Gaps = 31/338 (9%)
Query: 20 PVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGIL 79
PV++VP+ P FLPDP G LYT G + ++ L KLPFTIPELV +PCRS+DGIL
Sbjct: 60 PVLQVPTHVEE--PAFLPDPNDGSLYTLGSKNNEG-LTKLPFTIPELVQASPCRSSDGIL 116
Query: 80 YTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHD 139
Y GKK D W++ID LTG ++ S F ++ C S +Y+ RTEY I M+D
Sbjct: 117 YMGKKQDIWYVIDLLTGEKQQT----LSSAFA---DSLCPSTSL--LYLGRTEYTITMYD 167
Query: 140 SKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTP 199
+K +WN T+FDY + D+ DY HF S +G V++ D ++GD++W N+ +P
Sbjct: 168 TKTRELRWNATYFDYAASLPEDDV--DYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASP 225
Query: 200 VVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLK-------NSNIELYPTLY 252
VVA Y+ R+GL V ++ +TL ++ + + K + +L PTLY
Sbjct: 226 VVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLY 285
Query: 253 VGEHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTETLKTNAPRYE----PIKNIHY-- 306
VG+++ LYA S+V + + G L+EGP T+ + T + E P ++ +
Sbjct: 286 VGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGV-TIGDKGECVITPSTDVKFDP 344
Query: 307 --KLSDLNLHVSAPYLLLGHYKVP-ELTTSWIPHLPNS 341
K + ++ +LL+GH++ P +T + PN+
Sbjct: 345 GLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNN 382
>BC130405-1|AAI30406.1| 977|Homo sapiens endoplasmic reticulum to
nucleus signalling 1 protein.
Length = 977
Score = 464 bits (1143), Expect = e-130
Identities = 224/399 (56%), Positives = 289/399 (72%), Gaps = 7/399 (1%)
Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535
+GKI+F VLG G EGT VYRG FD RDVAVKR+LPECF+FADREV LLRESD H +V
Sbjct: 566 VGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNV 625
Query: 536 VRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIV 595
+RY+CTE+D+QF+YIA+ELC+ATLQ+YVE+K ++ + +L+Q T GL+HLHS++IV
Sbjct: 626 IRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIV 685
Query: 596 HRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN- 654
HRD+KPHN+L+SMP+ G+++AMISDFGL KKL +GR SFSRRSGV GT+GWIAPEM++
Sbjct: 686 HRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSE 745
Query: 655 --GERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEE-EL 711
E T ++DIFS GCVFYYV+S+G HPFG L+RQANIL G +LD L PE+ E
Sbjct: 746 DCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLH---PEKHED 802
Query: 712 VVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPL 771
V+ + LI MI+ P RP + +LK+P FW + L F QDVSD++E + L
Sbjct: 803 VIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQL 862
Query: 772 ERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSL 831
ERGG V++ DWR + + DLR RTY+G V LLRA+RNKKHHYREL ++VR++L
Sbjct: 863 ERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETL 922
Query: 832 GKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYY 870
G LPD FV Y+ +RFP LL H + M+ E + Q YY
Sbjct: 923 GSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYY 961
Score = 188 bits (458), Expect = 8e-47
Identities = 119/338 (35%), Positives = 184/338 (54%), Gaps = 31/338 (9%)
Query: 20 PVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGIL 79
PV++VP+ P FLPDP G LYT G + ++ L KLPFTIPELV +PCRS+DGIL
Sbjct: 60 PVLQVPTHVEE--PAFLPDPNDGSLYTLGSKNNEG-LTKLPFTIPELVQASPCRSSDGIL 116
Query: 80 YTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHD 139
Y GKK D W++ID LTG ++ S F ++ C S +Y+ RTEY I M+D
Sbjct: 117 YMGKKQDIWYVIDLLTGEKQQT----LSSAFA---DSLCPSTSL--LYLGRTEYTITMYD 167
Query: 140 SKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTP 199
+K +WN T+FDY + D+ DY HF S +G V++ D ++GD++W N+ +P
Sbjct: 168 TKTRELRWNATYFDYAASLPEDDV--DYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASP 225
Query: 200 VVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLK-------NSNIELYPTLY 252
VVA Y+ R+GL V ++ +TL ++ + + K + +L PTLY
Sbjct: 226 VVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLY 285
Query: 253 VGEHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTETLKTNAPRYE----PIKNIHY-- 306
VG+++ LYA S+V + + G L+EGP T+ + T + E P ++ +
Sbjct: 286 VGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGV-TIGDKGECVITPSTDVKFDP 344
Query: 307 --KLSDLNLHVSAPYLLLGHYKVP-ELTTSWIPHLPNS 341
K + ++ +LL+GH++ P +T + PN+
Sbjct: 345 GLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNN 382
>AB209869-1|BAD93106.1| 1006|Homo sapiens endoplasmic reticulum to
nucleus signalling 1 isoform 1 variant protein.
Length = 1006
Score = 464 bits (1143), Expect = e-130
Identities = 224/399 (56%), Positives = 289/399 (72%), Gaps = 7/399 (1%)
Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535
+GKI+F VLG G EGT VYRG FD RDVAVKR+LPECF+FADREV LLRESD H +V
Sbjct: 595 VGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNV 654
Query: 536 VRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIV 595
+RY+CTE+D+QF+YIA+ELC+ATLQ+YVE+K ++ + +L+Q T GL+HLHS++IV
Sbjct: 655 IRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIV 714
Query: 596 HRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN- 654
HRD+KPHN+L+SMP+ G+++AMISDFGL KKL +GR SFSRRSGV GT+GWIAPEM++
Sbjct: 715 HRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSE 774
Query: 655 --GERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEE-EL 711
E T ++DIFS GCVFYYV+S+G HPFG L+RQANIL G +LD L PE+ E
Sbjct: 775 DCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLH---PEKHED 831
Query: 712 VVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPL 771
V+ + LI MI+ P RP + +LK+P FW + L F QDVSD++E + L
Sbjct: 832 VIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQL 891
Query: 772 ERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSL 831
ERGG V++ DWR + + DLR RTY+G V LLRA+RNKKHHYREL ++VR++L
Sbjct: 892 ERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETL 951
Query: 832 GKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYY 870
G LPD FV Y+ +RFP LL H + M+ E + Q YY
Sbjct: 952 GSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYY 990
Score = 188 bits (458), Expect = 8e-47
Identities = 119/338 (35%), Positives = 184/338 (54%), Gaps = 31/338 (9%)
Query: 20 PVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGIL 79
PV++VP+ P FLPDP G LYT G + ++ L KLPFTIPELV +PCRS+DGIL
Sbjct: 89 PVLQVPTHVEE--PAFLPDPNDGSLYTLGSKNNEG-LTKLPFTIPELVQASPCRSSDGIL 145
Query: 80 YTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHD 139
Y GKK D W++ID LTG ++ S F ++ C S +Y+ RTEY I M+D
Sbjct: 146 YMGKKQDIWYVIDLLTGEKQQT----LSSAFA---DSLCPSTSL--LYLGRTEYTITMYD 196
Query: 140 SKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTP 199
+K +WN T+FDY + D+ DY HF S +G V++ D ++GD++W N+ +P
Sbjct: 197 TKTRELRWNATYFDYAASLPEDDV--DYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASP 254
Query: 200 VVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLK-------NSNIELYPTLY 252
VVA Y+ R+GL V ++ +TL ++ + + K + +L PTLY
Sbjct: 255 VVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLY 314
Query: 253 VGEHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTETLKTNAPRYE----PIKNIHY-- 306
VG+++ LYA S+V + + G L+EGP T+ + T + E P ++ +
Sbjct: 315 VGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGV-TIGDKGECVITPSTDVKFDP 373
Query: 307 --KLSDLNLHVSAPYLLLGHYKVP-ELTTSWIPHLPNS 341
K + ++ +LL+GH++ P +T + PN+
Sbjct: 374 GLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNN 411
>AF059198-1|AAC25991.1| 977|Homo sapiens protein
kinase/endoribonulcease protein.
Length = 977
Score = 463 bits (1142), Expect = e-129
Identities = 224/399 (56%), Positives = 288/399 (72%), Gaps = 7/399 (1%)
Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535
+GKI+F VLG G EGT VYRG FD RDVAVKR+LPECF+FADREV LLRESD H +V
Sbjct: 566 VGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNV 625
Query: 536 VRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIV 595
+RY+CTE+D+QF+YIA+ELC+ATLQ+YVE+K ++ + +L+Q T GL+HLHS++IV
Sbjct: 626 IRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIV 685
Query: 596 HRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN- 654
HRD+KPHN+L+SMP+ G+++AMISDFGL KKL +GR SFSRRSGV GT+GWIAPEM++
Sbjct: 686 HRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSE 745
Query: 655 --GERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEE-EL 711
E T ++DIFS GCVFYYV+S+G HPFG L+RQANIL G +LD L PE+ E
Sbjct: 746 DCKENPTYTVDIFSAGCVFYYVVSEGSHPFGKSLQRQANILLGACSLDCLH---PEKHED 802
Query: 712 VVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPL 771
V+ + LI MI+ P RP +LK+P FW + L F QDVSD++E + L
Sbjct: 803 VIARELIEKMIAMDPQKRPSANDVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQL 862
Query: 772 ERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSL 831
ERGG V++ DWR + + DLR RTY+G V LLRA+RNKKHHYREL ++VR++L
Sbjct: 863 ERGGRAVVKMDWRENITDPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETL 922
Query: 832 GKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYY 870
G LPD FV Y+ +RFP LL H + M+ E + Q YY
Sbjct: 923 GTLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYY 961
Score = 187 bits (456), Expect = 1e-46
Identities = 119/338 (35%), Positives = 186/338 (55%), Gaps = 31/338 (9%)
Query: 20 PVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGIL 79
PV++VP+ P FLPDP G LYT G + ++ L KLPFTIPELV +PCRS+DGIL
Sbjct: 60 PVLQVPTHVEE--PAFLPDPNDGSLYTLGSKNNEG-LTKLPFTIPELVQASPCRSSDGIL 116
Query: 80 YTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHD 139
Y GKK D W++ID LTG ++ S F ++ C S +Y+ RTEY I M+D
Sbjct: 117 YMGKKQDIWYVIDLLTGEKQQT----LSSAFA---DSLCPSTSL--LYLGRTEYTITMYD 167
Query: 140 SKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTP 199
+K +WN T+FDY + ++ +D DY HF S +G V++ D ++GD++W N+ +P
Sbjct: 168 TKTRELRWNATYFDYAA-SLPEDE-GDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASP 225
Query: 200 VVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLK-------NSNIELYPTLY 252
VVA Y+ R+GL V ++ +TL ++ + + K + +L PTLY
Sbjct: 226 VVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLY 285
Query: 253 VGEHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTETLKTNAPRYE----PIKNIHY-- 306
VG+++ LYA S+V + + G L+EGP T+ + T + E P ++ +
Sbjct: 286 VGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGV-TIGDKGECVITPSTDVKFDP 344
Query: 307 --KLSDLNLHVSAPYLLLGHYKVP-ELTTSWIPHLPNS 341
K + ++ +LL+GH++ P +T + PN+
Sbjct: 345 GLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNN 382
>AK131280-1|BAD18455.1| 974|Homo sapiens protein ( Homo sapiens
cDNA FLJ16228 fis, clone FEBRA2008692, highly similar
to Homo sapiens IRE1b mRNA for protein
kinase/ribonuclease IRE1 beta. ).
Length = 974
Score = 400 bits (986), Expect = e-111
Identities = 201/399 (50%), Positives = 260/399 (65%), Gaps = 5/399 (1%)
Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535
+GKI+F VLG+G GTFV+RG F+ R VAVKRLL ECF REV LL+ESD H +V
Sbjct: 563 VGKISFNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQLLQESDRHPNV 622
Query: 536 VRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIV 595
+RY+CTER QF YIALELC A+LQ+YVE ++ +L+Q GL+HLHS+ IV
Sbjct: 623 LRYFCTERGPQFHYIALELCRASLQEYVENPDLDRGGLEPEVVLQQLMSGLAHLHSLHIV 682
Query: 596 HRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN- 654
HRD+KP N+L++ P G R ++SDFGL KKL GR SFS SG+ GT+GW+APE++
Sbjct: 683 HRDLKPGNILITGPDSQGLGRVVLSDFGLCKKLPAGRCSFSLHSGIPGTEGWMAPELLQL 742
Query: 655 --GERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712
+ T+++DIFS GCVFYYVLS G HPFGD L RQANILTG L HL++ + ++ V
Sbjct: 743 LPPDSPTSAVDIFSAGCVFYYVLSGGSHPFGDSLYRQANILTGAPCLAHLEEEVHDK--V 800
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLE 772
V + L+ AM+S P RP +L +P FW + L F QDVSD +E + LE
Sbjct: 801 VARDLVGAMLSPLPQPRPSAPQVLAHPFFWSRAKQLQFFQDVSDWLEKESEQEPLVRALE 860
Query: 773 RGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLG 832
GG V+R +W + + DLR R+Y+G V LLRA+RNKKHHYREL +VR +LG
Sbjct: 861 AGGCAVVRDNWHEHISMPLQTDLRKFRSYKGTSVRDLLRAVRNKKHHYRELPVEVRQALG 920
Query: 833 KLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYYP 871
++PDGFV Y+ RFP LL H M+ E + YYP
Sbjct: 921 QVPDGFVQYFTNRFPRLLLHTHRAMRSCASESLFLPYYP 959
Score = 147 bits (355), Expect = 3e-34
Identities = 100/320 (31%), Positives = 157/320 (49%), Gaps = 32/320 (10%)
Query: 20 PVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGIL 79
PV++ P + FL DP G LY G + QQ L KLPFTIPELV +PCRS+DG+
Sbjct: 116 PVIEGPMYVTEMA--FLSDPADGSLYILGTQ-KQQGLMKLPFTIPELVHASPCRSSDGVF 172
Query: 80 YTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHD 139
YTG+K D WF++DP +G ++ T +Y+ RT+Y + MHD
Sbjct: 173 YTGRKQDAWFVVDPESG--------------ETQMTLTTEGPSTPRLYIGRTQYTVTMHD 218
Query: 140 SKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTP 199
+ +WN T+ Y++ M Y + H S G +++ D +G ++W+ + G P
Sbjct: 219 PRAPALRWNTTYRRYSAPPMDGSP-GKYMS-HLASCGMGLLLTVDPGSGTVLWTQDLGVP 276
Query: 200 VVAAYLLDRDGLISVPFNSIGDDTL-------DHIMEDAKTLSNGKGLKNS-NIELYPTL 251
V+ Y +DGL +P ++ DTL HI A + L ++ + +L TL
Sbjct: 277 VMGVYTWHQDGLRQLPHLTLARDTLHFLALRWGHIRLPASGPRDTATLFSTLDTQLLMTL 336
Query: 252 YVGEHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTE--TLKTNAPRY-EPIKNIHYKL 308
YVG+ G Y +LV + G +GP+T+ TL+ + R P + Y
Sbjct: 337 YVGKDETGFYVSKALVHTGVALVPRGLTLAPADGPTTDEVTLQVSGEREGSPSTAVRYPS 396
Query: 309 SDLNLHVSAPYLLLGHYKVP 328
+ L + +LL+GH+++P
Sbjct: 397 GSVAL--PSQWLLIGHHELP 414
>AB047079-1|BAB21297.1| 925|Homo sapiens protein
kinase/ribonuclease IRE1 beta protein.
Length = 925
Score = 398 bits (981), Expect = e-110
Identities = 202/399 (50%), Positives = 259/399 (64%), Gaps = 5/399 (1%)
Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535
+GKI+F VLG G GTFV+RG F+ R VAVKRLL ECF REV LL+ESD H +V
Sbjct: 514 VGKISFNPKDVLGHGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQLLQESDRHPNV 573
Query: 536 VRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIV 595
+RY+CTER QF YIALELC A+LQ+YVE ++ +L+Q GL+HLHS+ IV
Sbjct: 574 LRYFCTERGPQFHYIALELCRASLQEYVENPDLDRGGLEPEVVLQQLMSGLAHLHSLHIV 633
Query: 596 HRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN- 654
HRD+KP N+L++ P G R ++SDFGL KKL GR SFS SG+ GT+GW+APE++
Sbjct: 634 HRDLKPGNILITGPDTQGLGRVVLSDFGLCKKLPAGRCSFSLHSGIPGTEGWMAPELLQL 693
Query: 655 --GERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712
T+++DIFS GCVFYYVLS G HPFGD L RQANILTG L HL++ + ++ V
Sbjct: 694 LPPNSPTSAVDIFSAGCVFYYVLSGGSHPFGDSLYRQANILTGVPCLAHLEEEVHDK--V 751
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLE 772
V + L+ AM+S P ARP +L +P FW + L F QDVSD +E + LE
Sbjct: 752 VARDLVAAMLSLLPQARPSAPQVLAHPFFWSRAKQLQFFQDVSDWLEKESEQEPLMRALE 811
Query: 773 RGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLG 832
GG V+R +W + + DLR R+Y+G V LLRA+RNKKHHYREL +VR +LG
Sbjct: 812 AGGCTVVRDNWHEHISMPLQIDLRKFRSYKGTSVRDLLRAVRNKKHHYRELPVEVRQALG 871
Query: 833 KLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYYP 871
++PDGFV Y+ RFP LL H M+ E + YYP
Sbjct: 872 QVPDGFVQYFTNRFPQLLLHTHRVMRSCASESLFLPYYP 910
Score = 147 bits (355), Expect = 3e-34
Identities = 106/345 (30%), Positives = 166/345 (48%), Gaps = 35/345 (10%)
Query: 20 PVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGIL 79
PV++ P + FL DP G LY G + Q L KLPFTIPELV +PCRS+DG+
Sbjct: 68 PVIEGPMYVTEMA--FLSDPADGSLYILGTQ-KQLGLMKLPFTIPELVHASPCRSSDGVF 124
Query: 80 YTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHD 139
YTG+K D WF++DP +G ++ T +Y+ RT+Y + MHD
Sbjct: 125 YTGRKQDAWFVVDPESG--------------ETQMTLTTAGPSTPRLYIGRTQYTVTMHD 170
Query: 140 SKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTP 199
+ +WN T+ Y++ M Y + H S G +++ D ++G ++W+ + G P
Sbjct: 171 PRAPALRWNTTYRRYSAPPMDGSP-GKYMS-HLASCGMGLLLTVDPESGAVLWTQDLGMP 228
Query: 200 VVAAYLLDRDGLISVPFNSIGDDTL-------DHIMEDAKTLSNGKGLKNS-NIELYPTL 251
V+ Y +DGL +P ++ DTL HI A + L ++ + +L TL
Sbjct: 229 VMGVYTWHQDGLRQLPHLTLARDTLHFLALRWGHIRLPASGPQDTATLFSALDTQLLMTL 288
Query: 252 YVGEHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTE--TLKTNAPRY-EPIKNIHYKL 308
YVG+ G Y +LV + G +GP+T+ TL+ + R P + Y
Sbjct: 289 YVGKDETGFYVSKALVHTGVALVPRGLTLAPTDGPTTDEVTLQVSGEREGSPSTAVRYPS 348
Query: 309 SDLNLHVSAPYLLLGHYKVPEL--TTSWIPH-LPNSNVLNLRDPQ 350
+ L + +LL+GH+++P + TT H P S R P+
Sbjct: 349 GSVAL--PSQWLLIGHHELPPVLHTTMLRVHPTPGSGTAETRPPE 391
>U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase
protein.
Length = 299
Score = 93.5 bits (222), Expect = 3e-18
Identities = 67/222 (30%), Positives = 106/222 (47%), Gaps = 15/222 (6%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEIL 579
D+E+ L R H HVV++Y DK+ YI LE CS ++ K + + L
Sbjct: 19 DKEIELHRILH-HKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 77
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ GL +LH +I+HRD+K N ++ + + DFGL+ +L RR
Sbjct: 78 RQIVSGLKYLHEQEILHRDLKLGNFFINEA-----MELKVGDFGLAARLEPLE---HRRR 129
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNL 699
+ GT +++PE++N + DI++LGCV Y +L G+ PF N+ +
Sbjct: 130 TICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTML-LGRPPF-----ETTNLKETYRCI 183
Query: 700 DHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+P L K LI +M+S P RP + I+++ F
Sbjct: 184 REARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF 225
>BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2
(Drosophila) protein.
Length = 685
Score = 93.5 bits (222), Expect = 3e-18
Identities = 67/222 (30%), Positives = 106/222 (47%), Gaps = 15/222 (6%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEIL 579
D+E+ L R H HVV++Y DK+ YI LE CS ++ K + + L
Sbjct: 128 DKEIELHRILH-HKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 186
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ GL +LH +I+HRD+K N ++ + + DFGL+ +L RR
Sbjct: 187 RQIVSGLKYLHEQEILHRDLKLGNFFINEA-----MELKVGDFGLAARLEPLE---HRRR 238
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNL 699
+ GT +++PE++N + DI++LGCV Y +L G+ PF N+ +
Sbjct: 239 TICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTML-LGRPPF-----ETTNLKETYRCI 292
Query: 700 DHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+P L K LI +M+S P RP + I+++ F
Sbjct: 293 REARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF 334
>AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens
cDNA FLJ40844 fis, clone TRACH2014356, highly similar to
SERINE/THREONINE-PROTEIN KINASE SNK (EC 2.7.1.-). ).
Length = 372
Score = 93.5 bits (222), Expect = 3e-18
Identities = 67/222 (30%), Positives = 106/222 (47%), Gaps = 15/222 (6%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEIL 579
D+E+ L R H HVV++Y DK+ YI LE CS ++ K + + L
Sbjct: 121 DKEIELHRILH-HKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 179
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ GL +LH +I+HRD+K N ++ + + DFGL+ +L RR
Sbjct: 180 RQIVSGLKYLHEQEILHRDLKLGNFFINEA-----MELKVGDFGLAARLEPLE---HRRR 231
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNL 699
+ GT +++PE++N + DI++LGCV Y +L G+ PF N+ +
Sbjct: 232 TICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTML-LGRPPF-----ETTNLKETYRCI 285
Query: 700 DHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+P L K LI +M+S P RP + I+++ F
Sbjct: 286 REARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF 327
>AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 93.5 bits (222), Expect = 3e-18
Identities = 67/222 (30%), Positives = 106/222 (47%), Gaps = 15/222 (6%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEIL 579
D+E+ L R H HVV++Y DK+ YI LE CS ++ K + + L
Sbjct: 128 DKEIELHRILH-HKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 186
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ GL +LH +I+HRD+K N ++ + + DFGL+ +L RR
Sbjct: 187 RQIVSGLKYLHEQEILHRDLKLGNFFINEA-----MELKVGDFGLAARLEPLE---HRRR 238
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNL 699
+ GT +++PE++N + DI++LGCV Y +L G+ PF N+ +
Sbjct: 239 TICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTML-LGRPPF-----ETTNLKETYRCI 292
Query: 700 DHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+P L K LI +M+S P RP + I+++ F
Sbjct: 293 REARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF 334
>AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 93.5 bits (222), Expect = 3e-18
Identities = 67/222 (30%), Positives = 106/222 (47%), Gaps = 15/222 (6%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEIL 579
D+E+ L R H HVV++Y DK+ YI LE CS ++ K + + L
Sbjct: 128 DKEIELHRILH-HKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 186
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ GL +LH +I+HRD+K N ++ + + DFGL+ +L RR
Sbjct: 187 RQIVSGLKYLHEQEILHRDLKLGNFFINEA-----MELKVGDFGLAARLEPLE---HRRR 238
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNL 699
+ GT +++PE++N + DI++LGCV Y +L G+ PF N+ +
Sbjct: 239 TICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTML-LGRPPF-----ETTNLKETYRCI 292
Query: 700 DHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+P L K LI +M+S P RP + I+++ F
Sbjct: 293 REARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF 334
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 8 protein.
Length = 692
Score = 91.9 bits (218), Expect = 1e-17
Identities = 77/282 (27%), Positives = 142/282 (50%), Gaps = 24/282 (8%)
Query: 481 FQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLPECFTFADREVAL----LRESDAHAHV 535
++ +V+G+G G + D++ V +K++ E T +R+ A + + H +V
Sbjct: 4 YERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNV 63
Query: 536 VRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSV-EILRQATMGLSHLHSMD 593
+ YY + + IA+E TL ++++K+ N + +++ Q + L H+H+
Sbjct: 64 IEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL 123
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+K N+LL + I DFG+SK L+ S S+ V GT +I+PE+
Sbjct: 124 ILHRDLKTQNILLDKH----RMVVKIGDFGISKILS----SKSKAYTVVGTPCYISPELC 175
Query: 654 NGERTTTSIDIFSLGCVFYYVLS-KGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712
G+ DI++LGCV Y + S K ++ I++G + D+ PE
Sbjct: 176 EGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTF-APISDRYSPE---- 230
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDV 754
++ L+ +++S +P+ RPP I+ P+ C +++LN DV
Sbjct: 231 -LRQLVLSLLSLEPAQRPPLSHIMAQPL--CIRALLNLHTDV 269
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 91.9 bits (218), Expect = 1e-17
Identities = 77/282 (27%), Positives = 142/282 (50%), Gaps = 24/282 (8%)
Query: 481 FQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLPECFTFADREVAL----LRESDAHAHV 535
++ +V+G+G G + D++ V +K++ E T +R+ A + + H +V
Sbjct: 4 YERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNV 63
Query: 536 VRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSV-EILRQATMGLSHLHSMD 593
+ YY + + IA+E TL ++++K+ N + +++ Q + L H+H+
Sbjct: 64 IEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL 123
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+K N+LL + I DFG+SK L+ S S+ V GT +I+PE+
Sbjct: 124 ILHRDLKTQNILLDKH----RMVVKIGDFGISKILS----SKSKAYTVVGTPCYISPELC 175
Query: 654 NGERTTTSIDIFSLGCVFYYVLS-KGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712
G+ DI++LGCV Y + S K ++ I++G + D+ PE
Sbjct: 176 EGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTF-APISDRYSPE---- 230
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDV 754
++ L+ +++S +P+ RPP I+ P+ C +++LN DV
Sbjct: 231 -LRQLVLSLLSLEPAQRPPLSHIMAQPL--CIRALLNLHTDV 269
>AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8
protein.
Length = 692
Score = 91.9 bits (218), Expect = 1e-17
Identities = 77/282 (27%), Positives = 142/282 (50%), Gaps = 24/282 (8%)
Query: 481 FQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLPECFTFADREVAL----LRESDAHAHV 535
++ +V+G+G G + D++ V +K++ E T +R+ A + + H +V
Sbjct: 4 YERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNV 63
Query: 536 VRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSV-EILRQATMGLSHLHSMD 593
+ YY + + IA+E TL ++++K+ N + +++ Q + L H+H+
Sbjct: 64 IEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL 123
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+K N+LL + I DFG+SK L+ S S+ V GT +I+PE+
Sbjct: 124 ILHRDLKTQNILLDKH----RMVVKIGDFGISKILS----SKSKAYTVVGTPCYISPELC 175
Query: 654 NGERTTTSIDIFSLGCVFYYVLS-KGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712
G+ DI++LGCV Y + S K ++ I++G + D+ PE
Sbjct: 176 EGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTF-APISDRYSPE---- 230
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDV 754
++ L+ +++S +P+ RPP I+ P+ C +++LN DV
Sbjct: 231 -LRQLVLSLLSLEPAQRPPLSHIMAQPL--CIRALLNLHTDV 269
>AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a
protein.
Length = 692
Score = 91.9 bits (218), Expect = 1e-17
Identities = 77/282 (27%), Positives = 142/282 (50%), Gaps = 24/282 (8%)
Query: 481 FQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLPECFTFADREVAL----LRESDAHAHV 535
++ +V+G+G G + D++ V +K++ E T +R+ A + + H +V
Sbjct: 4 YERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNV 63
Query: 536 VRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSV-EILRQATMGLSHLHSMD 593
+ YY + + IA+E TL ++++K+ N + +++ Q + L H+H+
Sbjct: 64 IEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL 123
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+K N+LL + I DFG+SK L+ S S+ V GT +I+PE+
Sbjct: 124 ILHRDLKTQNILLDKH----RMVVKIGDFGISKILS----SKSKAYTVVGTPCYISPELC 175
Query: 654 NGERTTTSIDIFSLGCVFYYVLS-KGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712
G+ DI++LGCV Y + S K ++ I++G + D+ PE
Sbjct: 176 EGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTF-APISDRYSPE---- 230
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDV 754
++ L+ +++S +P+ RPP I+ P+ C +++LN DV
Sbjct: 231 -LRQLVLSLLSLEPAQRPPLSHIMAQPL--CIRALLNLHTDV 269
>L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-dependent
protein kinase isoform A protein.
Length = 306
Score = 89.8 bits (213), Expect = 4e-17
Identities = 69/247 (27%), Positives = 123/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 3 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 60
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 61 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 115
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q T D+ D +
Sbjct: 116 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGTYDFPSPEWDTV 174
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 175 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 227
Query: 766 GAEHPLE 772
A L+
Sbjct: 228 NARRKLK 234
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 88.6 bits (210), Expect = 9e-17
Identities = 67/228 (29%), Positives = 118/228 (51%), Gaps = 16/228 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV++L+E H +V+ + +K + LEL + L D++ +K + + ++ E
Sbjct: 62 EREVSILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLT-EEEATEF 119
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+Q G+ +LHS+ I H D+KP N++L + + R I DFGL+ K++ G +
Sbjct: 120 LKQILNGVYYLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFG----NEF 174
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQ-ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF GD + AN+ +
Sbjct: 175 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANVSAVN 233
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCK 744
Y + D+ + K IR ++ P R + L++P W K
Sbjct: 234 YEFE--DEYFSNTS-ALAKDFIRRLLVKDPKKRMTIQDSLQHP--WIK 276
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 88.6 bits (210), Expect = 9e-17
Identities = 67/228 (29%), Positives = 118/228 (51%), Gaps = 16/228 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV++L+E H +V+ + +K + LEL + L D++ +K + + ++ E
Sbjct: 62 EREVSILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLT-EEEATEF 119
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+Q G+ +LHS+ I H D+KP N++L + + R I DFGL+ K++ G +
Sbjct: 120 LKQILNGVYYLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFG----NEF 174
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQ-ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF GD + AN+ +
Sbjct: 175 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANVSAVN 233
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCK 744
Y + D+ + K IR ++ P R + L++P W K
Sbjct: 234 YEFE--DEYFSNTS-ALAKDFIRRLLVKDPKKRMTIQDSLQHP--WIK 276
>BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protein
kinase 1 protein.
Length = 367
Score = 88.6 bits (210), Expect = 9e-17
Identities = 67/228 (29%), Positives = 118/228 (51%), Gaps = 16/228 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV++L+E H +V+ + +K + LEL + L D++ +K + + ++ E
Sbjct: 62 EREVSILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLT-EEEATEF 119
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+Q G+ +LHS+ I H D+KP N++L + + R I DFGL+ K++ G +
Sbjct: 120 LKQILNGVYYLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFG----NEF 174
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQ-ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF GD + AN+ +
Sbjct: 175 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANVSAVN 233
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCK 744
Y + D+ + K IR ++ P R + L++P W K
Sbjct: 234 YEFE--DEYFSNTS-ALAKDFIRRLLVKDPKKRMTIQDSLQHP--WIK 276
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 88.6 bits (210), Expect = 9e-17
Identities = 67/228 (29%), Positives = 118/228 (51%), Gaps = 16/228 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV++L+E H +V+ + +K + LEL + L D++ +K + + ++ E
Sbjct: 62 EREVSILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLT-EEEATEF 119
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+Q G+ +LHS+ I H D+KP N++L + + R I DFGL+ K++ G +
Sbjct: 120 LKQILNGVYYLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFG----NEF 174
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQ-ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF GD + AN+ +
Sbjct: 175 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANVSAVN 233
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCK 744
Y + D+ + K IR ++ P R + L++P W K
Sbjct: 234 YEFE--DEYFSNTS-ALAKDFIRRLLVKDPKKRMTIQDSLQHP--WIK 276
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 88.6 bits (210), Expect = 9e-17
Identities = 67/228 (29%), Positives = 118/228 (51%), Gaps = 16/228 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV++L+E H +V+ + +K + LEL + L D++ +K + + ++ E
Sbjct: 62 EREVSILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLT-EEEATEF 119
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+Q G+ +LHS+ I H D+KP N++L + + R I DFGL+ K++ G +
Sbjct: 120 LKQILNGVYYLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFG----NEF 174
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQ-ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF GD + AN+ +
Sbjct: 175 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANVSAVN 233
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCK 744
Y + D+ + K IR ++ P R + L++P W K
Sbjct: 234 YEFE--DEYFSNTS-ALAKDFIRRLLVKDPKKRMTIQDSLQHP--WIK 276
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 88.6 bits (210), Expect = 9e-17
Identities = 67/228 (29%), Positives = 118/228 (51%), Gaps = 16/228 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV++L+E H +V+ + +K + LEL + L D++ +K + + ++ E
Sbjct: 62 EREVSILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLT-EEEATEF 119
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+Q G+ +LHS+ I H D+KP N++L + + R I DFGL+ K++ G +
Sbjct: 120 LKQILNGVYYLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFG----NEF 174
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQ-ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF GD + AN+ +
Sbjct: 175 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANVSAVN 233
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCK 744
Y + D+ + K IR ++ P R + L++P W K
Sbjct: 234 YEFE--DEYFSNTS-ALAKDFIRRLLVKDPKKRMTIQDSLQHP--WIK 276
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 88.6 bits (210), Expect = 9e-17
Identities = 67/228 (29%), Positives = 118/228 (51%), Gaps = 16/228 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV++L+E H +V+ + +K + LEL + L D++ +K + + ++ E
Sbjct: 62 EREVSILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLT-EEEATEF 119
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+Q G+ +LHS+ I H D+KP N++L + + R I DFGL+ K++ G +
Sbjct: 120 LKQILNGVYYLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFG----NEF 174
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQ-ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF GD + AN+ +
Sbjct: 175 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANVSAVN 233
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCK 744
Y + D+ + K IR ++ P R + L++P W K
Sbjct: 234 YEFE--DEYFSNTS-ALAKDFIRRLLVKDPKKRMTIQDSLQHP--WIK 276
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 88.6 bits (210), Expect = 9e-17
Identities = 67/228 (29%), Positives = 118/228 (51%), Gaps = 16/228 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV++L+E H +V+ + +K + LEL + L D++ +K + + ++ E
Sbjct: 65 EREVSILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLT-EEEATEF 122
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+Q G+ +LHS+ I H D+KP N++L + + R I DFGL+ K++ G +
Sbjct: 123 LKQILNGVYYLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFG----NEF 177
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQ-ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF GD + AN+ +
Sbjct: 178 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANVSAVN 236
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCK 744
Y + D+ + K IR ++ P R + L++P W K
Sbjct: 237 YEFE--DEYFSNTS-ALAKDFIRRLLVKDPKKRMTIQDSLQHP--WIK 279
>X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein.
Length = 603
Score = 87.8 bits (208), Expect = 2e-16
Identities = 58/216 (26%), Positives = 105/216 (48%), Gaps = 14/216 (6%)
Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMG 585
+ S AH HVV ++ D F ++ LELC + K+ + ++ LRQ +G
Sbjct: 104 IHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLG 163
Query: 586 LSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTD 645
+LH ++HRD+K N+ L+ ++ I DFGL+ K+ R+ + GT
Sbjct: 164 CQYLHRNRVIHRDLKLGNLFLNE-----DLEVKIGDFGLATKVEYDG---ERKKTLCGTP 215
Query: 646 GWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKI 705
+IAPE+++ + + +D++S+GC+ Y +L G+ PF ++ + + +
Sbjct: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLL-VGKPPFETSCLKETYL-----RIKKNEYS 269
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+P+ V LI+ M+ P+ARP +L F
Sbjct: 270 IPKHINPVAASLIQKMLQTDPTARPTINELLNDEFF 305
>U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-dependent
protein kinase II protein.
Length = 315
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>U01038-1|AAA56634.1| 603|Homo sapiens pLK protein.
Length = 603
Score = 87.8 bits (208), Expect = 2e-16
Identities = 58/216 (26%), Positives = 105/216 (48%), Gaps = 14/216 (6%)
Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMG 585
+ S AH HVV ++ D F ++ LELC + K+ + ++ LRQ +G
Sbjct: 104 IHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLG 163
Query: 586 LSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTD 645
+LH ++HRD+K N+ L+ ++ I DFGL+ K+ R+ + GT
Sbjct: 164 CQYLHRNRVIHRDLKLGNLFLNE-----DLEVKIGDFGLATKVEYDG---ERKKTLCGTP 215
Query: 646 GWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKI 705
+IAPE+++ + + +D++S+GC+ Y +L G+ PF ++ + + +
Sbjct: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLL-VGKPPFETSCLKETYL-----RIKKNEYS 269
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+P+ V LI+ M+ P+ARP +L F
Sbjct: 270 IPKHINPVAASLIQKMLQTDPTARPTINELLNDEFF 305
>BC034044-1|AAH34044.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein.
Length = 453
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 5 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 62
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 63 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 117
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 118 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 176
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 177 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 229
Query: 766 GAEHPLE 772
A L+
Sbjct: 230 NARRKLK 236
>BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 87.8 bits (208), Expect = 2e-16
Identities = 58/216 (26%), Positives = 105/216 (48%), Gaps = 14/216 (6%)
Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMG 585
+ S AH HVV ++ D F ++ LELC + K+ + ++ LRQ +G
Sbjct: 104 IHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLG 163
Query: 586 LSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTD 645
+LH ++HRD+K N+ L+ ++ I DFGL+ K+ R+ + GT
Sbjct: 164 CQYLHRNRVIHRDLKLGNLFLNE-----DLEVKIGDFGLATKVEYDG---ERKKTLCGTP 215
Query: 646 GWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKI 705
+IAPE+++ + + +D++S+GC+ Y +L G+ PF ++ + + +
Sbjct: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLL-VGKPPFETSCLKETYL-----RIKKNEYS 269
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+P+ V LI+ M+ P+ARP +L F
Sbjct: 270 IPKHINPVAASLIQKMLQTDPTARPTINELLNDEFF 305
>BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 87.8 bits (208), Expect = 2e-16
Identities = 58/216 (26%), Positives = 105/216 (48%), Gaps = 14/216 (6%)
Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMG 585
+ S AH HVV ++ D F ++ LELC + K+ + ++ LRQ +G
Sbjct: 104 IHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLG 163
Query: 586 LSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTD 645
+LH ++HRD+K N+ L+ ++ I DFGL+ K+ R+ + GT
Sbjct: 164 CQYLHRNRVIHRDLKLGNLFLNE-----DLEVKIGDFGLATKVEYDG---ERKKTLCGTP 215
Query: 646 GWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKI 705
+IAPE+++ + + +D++S+GC+ Y +L G+ PF ++ + + +
Sbjct: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLL-VGKPPFETSCLKETYL-----RIKKNEYS 269
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+P+ V LI+ M+ P+ARP +L F
Sbjct: 270 IPKHINPVAASLIQKMLQTDPTARPTINELLNDEFF 305
>BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 87.8 bits (208), Expect = 2e-16
Identities = 58/216 (26%), Positives = 105/216 (48%), Gaps = 14/216 (6%)
Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMG 585
+ S AH HVV ++ D F ++ LELC + K+ + ++ LRQ +G
Sbjct: 104 IHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLG 163
Query: 586 LSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTD 645
+LH ++HRD+K N+ L+ ++ I DFGL+ K+ R+ + GT
Sbjct: 164 CQYLHRNRVIHRDLKLGNLFLNE-----DLEVKIGDFGLATKVEYDG---ERKKTLCGTP 215
Query: 646 GWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKI 705
+IAPE+++ + + +D++S+GC+ Y +L G+ PF ++ + + +
Sbjct: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLL-VGKPPFETSCLKETYL-----RIKKNEYS 269
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+P+ V LI+ M+ P+ARP +L F
Sbjct: 270 IPKHINPVAASLIQKMLQTDPTARPTINELLNDEFF 305
>AL713896-5|CAI13788.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AL713896-4|CAI13789.1| 495|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 495
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AL713896-3|CAI13790.1| 529|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 529
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AL713896-2|CAI13791.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AL713896-1|CAI13787.1| 453|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 453
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 5 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 62
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 63 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 117
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 118 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 176
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 177 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 229
Query: 766 GAEHPLE 772
A L+
Sbjct: 230 NARRKLK 236
>AL596247-5|CAI13967.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AL596247-4|CAI13966.1| 495|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 495
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AL596247-3|CAI13965.1| 529|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 529
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AL596247-2|CAI13968.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AL596247-1|CAI13964.1| 453|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 453
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 5 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 62
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 63 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 117
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 118 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 176
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 177 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 229
Query: 766 GAEHPLE 772
A L+
Sbjct: 230 NARRKLK 236
>AF415197-1|AAM33514.1| 566|Homo sapiens
calcium/calmodulin-dependent protein kinase II gamma
protein.
Length = 566
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+
Sbjct: 48 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 105
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 106 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 160
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ + +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 161 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 219
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R + LK+P + C++S + + + VE C F
Sbjct: 220 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 272
Query: 766 GAEHPLE 772
A L+
Sbjct: 273 NARRKLK 279
>AF112472-1|AAD03744.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILXAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AF112471-1|AAD03743.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 517
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILXAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein
kinase protein.
Length = 603
Score = 87.4 bits (207), Expect = 2e-16
Identities = 58/216 (26%), Positives = 104/216 (48%), Gaps = 14/216 (6%)
Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMG 585
+ S AH HVV ++ D F ++ LELC K+ + ++ LRQ +G
Sbjct: 104 IHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLEPHKRRKALTEPEARYYLRQIVLG 163
Query: 586 LSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTD 645
+LH ++HRD+K N+ L+ ++ I DFGL+ K+ R+ + GT
Sbjct: 164 CQYLHRNRVIHRDLKLGNLFLNE-----DLEVKIGDFGLATKVEYDG---ERKKTLCGTP 215
Query: 646 GWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKI 705
+IAPE+++ + + +D++S+GC+ Y +L G+ PF ++ + + +
Sbjct: 216 NYIAPEVLSKKEHSFEVDVWSIGCIMYTLL-VGKPPFETSCLKETYL-----RIKKNEYS 269
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+P+ V LI+ M+ P+ARP +L F
Sbjct: 270 IPKHINPVAASLIQKMLQTDPTARPTINELLNDEFF 305
>U23460-1|AAC99802.1| 664|Homo sapiens proline rich
calmodulin-dependent protein kinase protein.
Length = 664
Score = 87.4 bits (207), Expect = 2e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>BC019070-1|AAH19070.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II beta protein.
Length = 503
Score = 87.4 bits (207), Expect = 2e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 4 protein.
Length = 518
Score = 87.4 bits (207), Expect = 2e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 2 protein.
Length = 479
Score = 87.4 bits (207), Expect = 2e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 1 protein.
Length = 503
Score = 87.4 bits (207), Expect = 2e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AF140350-1|AAD42070.1| 449|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 7
subunit protein.
Length = 449
Score = 87.4 bits (207), Expect = 2e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AF083419-1|AAD42038.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e
subunit protein.
Length = 517
Score = 87.4 bits (207), Expect = 2e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AF081924-1|AAD42037.1| 492|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 6
subunit protein.
Length = 492
Score = 87.4 bits (207), Expect = 2e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AF081572-1|AAD42036.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e'
subunit protein.
Length = 503
Score = 87.4 bits (207), Expect = 2e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AF078803-1|AAD42035.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 87.4 bits (207), Expect = 2e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein.
Length = 603
Score = 87.0 bits (206), Expect = 3e-16
Identities = 57/211 (27%), Positives = 104/211 (49%), Gaps = 14/211 (6%)
Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMG 585
+ S AH HVV ++ D F ++ LELC + K+ + ++ LRQ +G
Sbjct: 104 IHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLG 163
Query: 586 LSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTD 645
+LH ++HRD+K N+ L+ ++ I DFGL+ K+ R+ + GT
Sbjct: 164 CQYLHRNRVIHRDLKLGNLFLNE-----DLEVKIGDFGLATKVEYDG---ERKKTLCGTP 215
Query: 646 GWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKI 705
+IAPE+++ + + +D++S+GC+ Y +L G+ PF ++ + + +
Sbjct: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLL-VGKPPFETSCLKETYL-----RIKKNEYS 269
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETIL 736
+P+ V LI+ M+ P+ARP +L
Sbjct: 270 IPKHINPVAASLIQKMLQTDPTARPTINELL 300
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 124
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V
Sbjct: 125 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 178
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 237
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y D + D I K IR ++ P+ R CE ++P
Sbjct: 238 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 277
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 124
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V
Sbjct: 125 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 178
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 237
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y D + D I K IR ++ P+ R CE ++P
Sbjct: 238 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 277
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 124
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V
Sbjct: 125 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 178
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 237
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y D + D I K IR ++ P+ R CE ++P
Sbjct: 238 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 277
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 124
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V
Sbjct: 125 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 178
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 237
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y D + D I K IR ++ P+ R CE ++P
Sbjct: 238 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 277
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 124
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V
Sbjct: 125 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 178
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 237
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y D + D I K IR ++ P+ R CE ++P
Sbjct: 238 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 277
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 124
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V
Sbjct: 125 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 178
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 237
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y D + D I K IR ++ P+ R CE ++P
Sbjct: 238 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 277
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 124
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V
Sbjct: 125 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 178
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 237
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y D + D I K IR ++ P+ R CE ++P
Sbjct: 238 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 277
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 124
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V
Sbjct: 125 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 178
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 237
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y D + D I K IR ++ P+ R CE ++P
Sbjct: 238 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 277
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 124
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V
Sbjct: 125 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 178
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 237
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y D + D I K IR ++ P+ R CE ++P
Sbjct: 238 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 277
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 124
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V
Sbjct: 125 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 178
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 237
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y D + D I K IR ++ P+ R CE ++P
Sbjct: 238 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 277
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 124
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V
Sbjct: 125 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 178
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 237
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y D + D I K IR ++ P+ R CE ++P
Sbjct: 238 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 277
>AK222703-1|BAD96423.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase IIB isoform
2 variant protein.
Length = 542
Score = 86.6 bits (205), Expect = 4e-16
Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705
PE++ E +DI++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + VE C F
Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMYRQETVE-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 85.8 bits (203), Expect = 7e-16
Identities = 66/230 (28%), Positives = 113/230 (49%), Gaps = 23/230 (10%)
Query: 467 MEIGEGEMK-IGKITFQTDQVLGKGCEGTFVYRGTF-DKRDVAV------KRLLPECFTF 518
ME G G + +GK F ++G G V++G +K D+ V K+ L + T
Sbjct: 1 MEPGRGGTETVGKFEFSRKDLIGHGAFAV-VFKGRHREKHDLEVAVKCINKKNLAKSQTL 59
Query: 519 ADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVE 577
+E+ +L+E H ++V Y + Y+ +E C+ L DY+ D++
Sbjct: 60 LGKEIKILKELK-HENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLS--EDTIR 116
Query: 578 ILRQATMGLSHL-HSMDIVHRDVKPHNVLLSMPSG----TGEVRAMISDFGLSKKLNIGR 632
+ Q G L HS I+HRD+KP N+LLS P+G +R I+DFG ++ L
Sbjct: 117 LFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNM 176
Query: 633 VSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
++ + + G+ ++APE+I + D++S+G + Y L+ G+ PF
Sbjct: 177 MA----ATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLT-GKAPF 221
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 85.8 bits (203), Expect = 7e-16
Identities = 66/230 (28%), Positives = 113/230 (49%), Gaps = 23/230 (10%)
Query: 467 MEIGEGEMK-IGKITFQTDQVLGKGCEGTFVYRGTF-DKRDVAV------KRLLPECFTF 518
ME G G + +GK F ++G G V++G +K D+ V K+ L + T
Sbjct: 17 MEPGRGGTETVGKFEFSRKDLIGHGAFAV-VFKGRHREKHDLEVAVKCINKKNLAKSQTL 75
Query: 519 ADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVE 577
+E+ +L+E H ++V Y + Y+ +E C+ L DY+ D++
Sbjct: 76 LGKEIKILKELK-HENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLS--EDTIR 132
Query: 578 ILRQATMGLSHL-HSMDIVHRDVKPHNVLLSMPSG----TGEVRAMISDFGLSKKLNIGR 632
+ Q G L HS I+HRD+KP N+LLS P+G +R I+DFG ++ L
Sbjct: 133 LFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNM 192
Query: 633 VSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
++ + + G+ ++APE+I + D++S+G + Y L+ G+ PF
Sbjct: 193 MA----ATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLT-GKAPF 237
>U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine
protein kinase PRK protein.
Length = 607
Score = 85.0 bits (201), Expect = 1e-15
Identities = 64/220 (29%), Positives = 103/220 (46%), Gaps = 15/220 (6%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQ 581
E+ L R+ H H+VR+ D YI LELCS ++ K + + + LRQ
Sbjct: 71 EIELHRDLQ-HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQ 129
Query: 582 ATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGV 641
GL +LH I+HRD+K N + T + + DFGL+ +L R+ +
Sbjct: 130 ILSGLKYLHQRGILHRDLKLGNFFI-----TENMELKVGDFGLAARLEPPE---QRKKTI 181
Query: 642 TGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDH 701
GT ++APE++ + D++SLGCV Y +L G PF A++ +
Sbjct: 182 CGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLC-GSPPF-----ETADLKETYRCIKQ 235
Query: 702 LDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+ LP + + L+ A++ A P RP + IL++ F
Sbjct: 236 VHYTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFF 275
>BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein.
Length = 344
Score = 85.0 bits (201), Expect = 1e-15
Identities = 66/247 (26%), Positives = 120/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ S V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HQMGVVHRDLKPENLLLASKSKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV----LRRQANILTGDYNLDHLDKI 705
PE++ + +D+++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDMWACG-VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P C++S + + + V+ C F
Sbjct: 242 TPE-----AKDLINKMLTINPAKRITASEALKHPWI-CQRSTVASMMHRQETVD-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 85.0 bits (201), Expect = 1e-15
Identities = 64/220 (29%), Positives = 103/220 (46%), Gaps = 15/220 (6%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQ 581
E+ L R+ H H+VR+ D YI LELCS ++ K + + + LRQ
Sbjct: 110 EIELHRDLQ-HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQ 168
Query: 582 ATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGV 641
GL +LH I+HRD+K N + T + + DFGL+ +L R+ +
Sbjct: 169 ILSGLKYLHQRGILHRDLKLGNFFI-----TENMELKVGDFGLAARLEPPE---QRKKTI 220
Query: 642 TGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDH 701
GT ++APE++ + D++SLGCV Y +L G PF A++ +
Sbjct: 221 CGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLC-GSPPF-----ETADLKETYRCIKQ 274
Query: 702 LDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+ LP + + L+ A++ A P RP + IL++ F
Sbjct: 275 VHYTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFF 314
>AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 85.0 bits (201), Expect = 1e-15
Identities = 64/220 (29%), Positives = 103/220 (46%), Gaps = 15/220 (6%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQ 581
E+ L R+ H H+VR+ D YI LELCS ++ K + + + LRQ
Sbjct: 110 EIELHRDLQ-HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQ 168
Query: 582 ATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGV 641
GL +LH I+HRD+K N + T + + DFGL+ +L R+ +
Sbjct: 169 ILSGLKYLHQRGILHRDLKLGNFFI-----TENMELKVGDFGLAARLEPPE---QRKKTI 220
Query: 642 TGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDH 701
GT ++APE++ + D++SLGCV Y +L G PF A++ +
Sbjct: 221 CGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLC-GSPPF-----ETADLKETYRCIKQ 274
Query: 702 LDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+ LP + + L+ A++ A P RP + IL++ F
Sbjct: 275 VHYTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFF 314
>AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 85.0 bits (201), Expect = 1e-15
Identities = 64/220 (29%), Positives = 103/220 (46%), Gaps = 15/220 (6%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQ 581
E+ L R+ H H+VR+ D YI LELCS ++ K + + + LRQ
Sbjct: 110 EIELHRDLQ-HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQ 168
Query: 582 ATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGV 641
GL +LH I+HRD+K N + T + + DFGL+ +L R+ +
Sbjct: 169 ILSGLKYLHQRGILHRDLKLGNFFI-----TENMELKVGDFGLAARLEPPE---QRKKTI 220
Query: 642 TGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDH 701
GT ++APE++ + D++SLGCV Y +L G PF A++ +
Sbjct: 221 CGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLC-GSPPF-----ETADLKETYRCIKQ 274
Query: 702 LDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+ LP + + L+ A++ A P RP + IL++ F
Sbjct: 275 VHYTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFF 314
>AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine
protein kinase protein.
Length = 646
Score = 85.0 bits (201), Expect = 1e-15
Identities = 64/220 (29%), Positives = 103/220 (46%), Gaps = 15/220 (6%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQ 581
E+ L R+ H H+VR+ D YI LELCS ++ K + + + LRQ
Sbjct: 110 EIELHRDLQ-HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQ 168
Query: 582 ATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGV 641
GL +LH I+HRD+K N + T + + DFGL+ +L R+ +
Sbjct: 169 ILSGLKYLHQRGILHRDLKLGNFFI-----TENMELKVGDFGLAARLEPPE---QRKKTI 220
Query: 642 TGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDH 701
GT ++APE++ + D++SLGCV Y +L G PF A++ +
Sbjct: 221 CGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLC-GSPPF-----ETADLKETYRCIKQ 274
Query: 702 LDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+ LP + + L+ A++ A P RP + IL++ F
Sbjct: 275 VHYTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFF 314
>AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 variant
protein.
Length = 621
Score = 85.0 bits (201), Expect = 1e-15
Identities = 64/220 (29%), Positives = 103/220 (46%), Gaps = 15/220 (6%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQ 581
E+ L R+ H H+VR+ D YI LELCS ++ K + + + LRQ
Sbjct: 85 EIELHRDLQ-HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQ 143
Query: 582 ATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGV 641
GL +LH I+HRD+K N + T + + DFGL+ +L R+ +
Sbjct: 144 ILSGLKYLHQRGILHRDLKLGNFFI-----TENMELKVGDFGLAARLEPPE---QRKKTI 195
Query: 642 TGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDH 701
GT ++APE++ + D++SLGCV Y +L G PF A++ +
Sbjct: 196 CGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLC-GSPPF-----ETADLKETYRCIKQ 249
Query: 702 LDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+ LP + + L+ A++ A P RP + IL++ F
Sbjct: 250 VHYTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFF 289
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 83.0 bits (196), Expect = 5e-15
Identities = 74/246 (30%), Positives = 120/246 (48%), Gaps = 20/246 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+L + H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 64 ENEIAVLHKIK-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEK-GFYTERDASRL 121
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+ Q + +LH + IVHRD+KP N+L S + + MISDFGLSK + G V
Sbjct: 122 IFQVLDAVKYLHDLGIVHRDLKPENLLYY--SLDEDSKIMISDFGLSKMEDPGSV----L 175
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 176 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDAKLFEQILKAE 234
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSI-LNFLQD 753
Y D + D I K IR ++ P R CE L++P ++ N Q
Sbjct: 235 YEFDSPYWDDISDS-----AKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQS 289
Query: 754 VSDQVE 759
VS+Q++
Sbjct: 290 VSEQIK 295
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 83.0 bits (196), Expect = 5e-15
Identities = 74/246 (30%), Positives = 120/246 (48%), Gaps = 20/246 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+L + H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 64 ENEIAVLHKIK-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEK-GFYTERDASRL 121
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+ Q + +LH + IVHRD+KP N+L S + + MISDFGLSK + G V
Sbjct: 122 IFQVLDAVKYLHDLGIVHRDLKPENLLYY--SLDEDSKIMISDFGLSKMEDPGSV----L 175
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 176 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDAKLFEQILKAE 234
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSI-LNFLQD 753
Y D + D I K IR ++ P R CE L++P ++ N Q
Sbjct: 235 YEFDSPYWDDISDS-----AKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQS 289
Query: 754 VSDQVE 759
VS+Q++
Sbjct: 290 VSEQIK 295
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 83.0 bits (196), Expect = 5e-15
Identities = 74/246 (30%), Positives = 120/246 (48%), Gaps = 20/246 (8%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+L + H ++V Y+ ++L S L D + +K F + D+ +
Sbjct: 64 ENEIAVLHKIK-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEK-GFYTERDASRL 121
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+ Q + +LH + IVHRD+KP N+L S + + MISDFGLSK + G V
Sbjct: 122 IFQVLDAVKYLHDLGIVHRDLKPENLLYY--SLDEDSKIMISDFGLSKMEDPGSV----L 175
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696
S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL +
Sbjct: 176 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDAKLFEQILKAE 234
Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSI-LNFLQD 753
Y D + D I K IR ++ P R CE L++P ++ N Q
Sbjct: 235 YEFDSPYWDDISDS-----AKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQS 289
Query: 754 VSDQVE 759
VS+Q++
Sbjct: 290 VSEQIK 295
>BC032784-1|AAH32784.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II delta protein.
Length = 478
Score = 83.0 bits (196), Expect = 5e-15
Identities = 66/247 (26%), Positives = 120/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q ++H
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILESVNHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H IVHRD+KP N+LL+ S V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HLNGIVHRDLKPENLLLASKSKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV----LRRQANILTGDYNLDHLDKI 705
PE++ + +D+++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDMWACG-VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P C++S + + + V+ C F
Sbjct: 242 TPE-----AKDLINKMLTINPAKRITASEALKHPWI-CQRSTVASMMHRQETVD-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AY987011-1|AAX88806.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
protein.
Length = 489
Score = 83.0 bits (196), Expect = 5e-15
Identities = 66/247 (26%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q ++H
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILESVNHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H IVHRD+KP N+LL+ S V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HLNGIVHRDLKPENLLLASKSKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV----LRRQANILTGDYNLDHLDKI 705
PE++ + +D+++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDMWACG-VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P + C++S + + + V+ C F
Sbjct: 242 TPE-----AKDLINKMLTINPAKRITASEALKHP-WTCQRSTVASMMHRQETVD-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional
calcium/calmodulin-dependent protein kinase II delta2
isoform protein.
Length = 499
Score = 83.0 bits (196), Expect = 5e-15
Identities = 66/247 (26%), Positives = 120/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q ++H
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILESVNHC 127
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H IVHRD+KP N+LL+ S V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 128 HLNGIVHRDLKPENLLLASKSKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV----LRRQANILTGDYNLDHLDKI 705
PE++ + +D+++ G V Y+L G PF D L +Q D+ D +
Sbjct: 183 PEVLRKDPYGKPVDMWACG-VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 241
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P C++S + + + V+ C F
Sbjct: 242 TPE-----AKDLINKMLTINPAKRITASEALKHPWI-CQRSTVASMMHRQETVD-CLKKF 294
Query: 766 GAEHPLE 772
A L+
Sbjct: 295 NARRKLK 301
>AB209288-1|BAD92525.1| 522|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
isoform 1 variant protein.
Length = 522
Score = 83.0 bits (196), Expect = 5e-15
Identities = 66/247 (26%), Positives = 120/247 (48%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q ++H
Sbjct: 100 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILESVNHC 157
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H IVHRD+KP N+LL+ S V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 158 HLNGIVHRDLKPENLLLASKSKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 212
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV----LRRQANILTGDYNLDHLDKI 705
PE++ + +D+++ G V Y+L G PF D L +Q D+ D +
Sbjct: 213 PEVLRKDPYGKPVDMWACG-VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 271
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ P+ R LK+P C++S + + + V+ C F
Sbjct: 272 TPE-----AKDLINKMLTINPAKRITASEALKHPWI-CQRSTVASMMHRQETVD-CLKKF 324
Query: 766 GAEHPLE 772
A L+
Sbjct: 325 NARRKLK 331
>U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein.
Length = 487
Score = 82.2 bits (194), Expect = 8e-15
Identities = 61/209 (29%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ VY+ + VA+K++ E +E++++++ D+ HVV+
Sbjct: 30 FDVLEKLGEGSYGS-VYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDS-PHVVK 87
Query: 538 YYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATM-GLSHLHSMDIVH 596
YY + +I +E C A + + N D + + Q+T+ GL +LH M +H
Sbjct: 88 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIH 147
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 148 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 199
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 200 GYNCVADIWSLG-ITAIEMAEGKRPYADI 227
>Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 81.4 bits (192), Expect = 1e-14
Identities = 61/209 (29%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ VY+ + VA+K++ E +E++++++ D+ HVV+
Sbjct: 30 FDVLEKLGEGSYGS-VYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDS-PHVVK 87
Query: 538 YYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATM-GLSHLHSMDIVH 596
YY + +I +E C A + + N D + + Q+T+ GL +LH M +H
Sbjct: 88 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIH 147
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 148 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 199
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 200 GYNCVADIWSLG-ITAIEMAEGKPPYADI 227
>Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 81.4 bits (192), Expect = 1e-14
Identities = 61/209 (29%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ VY+ + VA+K++ E +E++++++ D+ HVV+
Sbjct: 30 FDVLEKLGEGSYGS-VYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDS-PHVVK 87
Query: 538 YYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATM-GLSHLHSMDIVH 596
YY + +I +E C A + + N D + + Q+T+ GL +LH M +H
Sbjct: 88 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIH 147
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 148 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 199
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 200 GYNCVADIWSLG-ITAIEMAEGKPPYADI 227
>U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein
kinase Krs-2 protein.
Length = 487
Score = 81.4 bits (192), Expect = 1e-14
Identities = 61/209 (29%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ VY+ + VA+K++ E +E++++++ D+ HVV+
Sbjct: 30 FDVLEKLGEGSYGS-VYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDS-PHVVK 87
Query: 538 YYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATM-GLSHLHSMDIVH 596
YY + +I +E C A + + N D + + Q+T+ GL +LH M +H
Sbjct: 88 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIH 147
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 148 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 199
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 200 GYNCVADIWSLG-ITAIEMAEGKPPYADI 227
>BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 81.4 bits (192), Expect = 1e-14
Identities = 61/209 (29%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ VY+ + VA+K++ E +E++++++ D+ HVV+
Sbjct: 30 FDVLEKLGEGSYGS-VYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDS-PHVVK 87
Query: 538 YYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATM-GLSHLHSMDIVH 596
YY + +I +E C A + + N D + + Q+T+ GL +LH M +H
Sbjct: 88 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIH 147
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 148 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 199
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 200 GYNCVADIWSLG-ITAIEMAEGKPPYADI 227
>BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 81.4 bits (192), Expect = 1e-14
Identities = 61/209 (29%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ VY+ + VA+K++ E +E++++++ D+ HVV+
Sbjct: 30 FDVLEKLGEGSYGS-VYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDS-PHVVK 87
Query: 538 YYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATM-GLSHLHSMDIVH 596
YY + +I +E C A + + N D + + Q+T+ GL +LH M +H
Sbjct: 88 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIH 147
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 148 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 199
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 200 GYNCVADIWSLG-ITAIEMAEGKPPYADI 227
>BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for
IMAGE:4400771) protein.
Length = 405
Score = 81.4 bits (192), Expect = 1e-14
Identities = 61/209 (29%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ VY+ + VA+K++ E +E++++++ D+ HVV+
Sbjct: 30 FDVLEKLGEGSYGS-VYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDS-PHVVK 87
Query: 538 YYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATM-GLSHLHSMDIVH 596
YY + +I +E C A + + N D + + Q+T+ GL +LH M +H
Sbjct: 88 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIH 147
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 148 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 199
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 200 GYNCVADIWSLG-ITAIEMAEGKPPYADI 227
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 81.4 bits (192), Expect = 1e-14
Identities = 82/272 (30%), Positives = 130/272 (47%), Gaps = 31/272 (11%)
Query: 481 FQTDQVLGKGCEGTFVYRGT--FDKRDVAVK-----RLLPECFTFADREVALLRESDAHA 533
++ ++ LGKG G V G + VA+K +L +RE+A+L+ + H
Sbjct: 34 YRLEKTLGKGQTG-LVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIE-HP 91
Query: 534 HVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592
HV++ + +K++ Y+ LE S L DY+ KK K ++ + RQ L HS
Sbjct: 92 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK-EARKFFRQIVSALDFCHSY 150
Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652
I HRD+KP N+LL + +R I+DFG++ L +G S G+ + PE+
Sbjct: 151 SICHRDLKPENLLLDEKN---NIR--IADFGMA-SLQVGD---SLLETSCGSPHYACPEV 201
Query: 653 INGER-TTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDHLDKILPEE 709
I GE+ D++S G V + L G PF D RQ + G +++ H I P+
Sbjct: 202 IKGEKYDGRRADMWSCG-VILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHF--IPPD- 257
Query: 710 ELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+ L+R MI +P R E I K+P +
Sbjct: 258 ----CQSLLRGMIEVEPEKRLSLEQIQKHPWY 285
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 81.4 bits (192), Expect = 1e-14
Identities = 82/272 (30%), Positives = 130/272 (47%), Gaps = 31/272 (11%)
Query: 481 FQTDQVLGKGCEGTFVYRGT--FDKRDVAVK-----RLLPECFTFADREVALLRESDAHA 533
++ ++ LGKG G V G + VA+K +L +RE+A+L+ + H
Sbjct: 34 YRLEKTLGKGQTG-LVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIE-HP 91
Query: 534 HVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592
HV++ + +K++ Y+ LE S L DY+ KK K ++ + RQ L HS
Sbjct: 92 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK-EARKFFRQIVSALDFCHSY 150
Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652
I HRD+KP N+LL + +R I+DFG++ L +G S G+ + PE+
Sbjct: 151 SICHRDLKPENLLLDEKN---NIR--IADFGMA-SLQVGD---SLLETSCGSPHYACPEV 201
Query: 653 INGER-TTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDHLDKILPEE 709
I GE+ D++S G V + L G PF D RQ + G +++ H I P+
Sbjct: 202 IKGEKYDGRRADMWSCG-VILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHF--IPPD- 257
Query: 710 ELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+ L+R MI +P R E I K+P +
Sbjct: 258 ----CQSLLRGMIEVEPEKRLSLEQIQKHPWY 285
>AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 81.4 bits (192), Expect = 1e-14
Identities = 61/209 (29%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ VY+ + VA+K++ E +E++++++ D+ HVV+
Sbjct: 30 FDVLEKLGEGSYGS-VYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDS-PHVVK 87
Query: 538 YYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATM-GLSHLHSMDIVH 596
YY + +I +E C A + + N D + + Q+T+ GL +LH M +H
Sbjct: 88 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIH 147
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 148 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 199
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 200 GYNCVADIWSLG-ITAIEMAEGKPPYADI 227
>AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 81.4 bits (192), Expect = 1e-14
Identities = 61/209 (29%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ VY+ + VA+K++ E +E++++++ D+ HVV+
Sbjct: 30 FDVLEKLGEGSYGS-VYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDS-PHVVK 87
Query: 538 YYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATM-GLSHLHSMDIVH 596
YY + +I +E C A + + N D + + Q+T+ GL +LH M +H
Sbjct: 88 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIH 147
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 148 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 199
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 200 GYNCVADIWSLG-ITAIEMAEGKPPYADI 227
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 81.4 bits (192), Expect = 1e-14
Identities = 82/272 (30%), Positives = 130/272 (47%), Gaps = 31/272 (11%)
Query: 481 FQTDQVLGKGCEGTFVYRGT--FDKRDVAVK-----RLLPECFTFADREVALLRESDAHA 533
++ ++ LGKG G V G + VA+K +L +RE+A+L+ + H
Sbjct: 34 YRLEKTLGKGQTG-LVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIE-HP 91
Query: 534 HVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592
HV++ + +K++ Y+ LE S L DY+ KK K ++ + RQ L HS
Sbjct: 92 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK-EARKFFRQIVSALDFCHSY 150
Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652
I HRD+KP N+LL + +R I+DFG++ L +G S G+ + PE+
Sbjct: 151 SICHRDLKPENLLLDEKN---NIR--IADFGMA-SLQVGD---SLLETSCGSPHYACPEV 201
Query: 653 INGER-TTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDHLDKILPEE 709
I GE+ D++S G V + L G PF D RQ + G +++ H I P+
Sbjct: 202 IKGEKYDGRRADMWSCG-VILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHF--IPPD- 257
Query: 710 ELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+ L+R MI +P R E I K+P +
Sbjct: 258 ----CQSLLRGMIEVEPEKRLSLEQIQKHPWY 285
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 81.4 bits (192), Expect = 1e-14
Identities = 82/272 (30%), Positives = 130/272 (47%), Gaps = 31/272 (11%)
Query: 481 FQTDQVLGKGCEGTFVYRGT--FDKRDVAVK-----RLLPECFTFADREVALLRESDAHA 533
++ ++ LGKG G V G + VA+K +L +RE+A+L+ + H
Sbjct: 50 YRLEKTLGKGQTG-LVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIE-HP 107
Query: 534 HVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592
HV++ + +K++ Y+ LE S L DY+ KK K ++ + RQ L HS
Sbjct: 108 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK-EARKFFRQIVSALDFCHSY 166
Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652
I HRD+KP N+LL + +R I+DFG++ L +G S G+ + PE+
Sbjct: 167 SICHRDLKPENLLLDEKN---NIR--IADFGMA-SLQVGD---SLLETSCGSPHYACPEV 217
Query: 653 INGER-TTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDHLDKILPEE 709
I GE+ D++S G V + L G PF D RQ + G +++ H I P+
Sbjct: 218 IKGEKYDGRRADMWSCG-VILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHF--IPPD- 273
Query: 710 ELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+ L+R MI +P R E I K+P +
Sbjct: 274 ----CQSLLRGMIEVEPEKRLSLEQIQKHPWY 301
>AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase 4
variant protein.
Length = 511
Score = 81.4 bits (192), Expect = 1e-14
Identities = 61/209 (29%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ VY+ + VA+K++ E +E++++++ D+ HVV+
Sbjct: 54 FDVLEKLGEGSYGS-VYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDS-PHVVK 111
Query: 538 YYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATM-GLSHLHSMDIVH 596
YY + +I +E C A + + N D + + Q+T+ GL +LH M +H
Sbjct: 112 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIH 171
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 172 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 223
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 224 GYNCVADIWSLG-ITAIEMAEGKPPYADI 251
>Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamma
subunit protein.
Length = 406
Score = 81.0 bits (191), Expect = 2e-14
Identities = 69/252 (27%), Positives = 116/252 (46%), Gaps = 31/252 (12%)
Query: 505 DVAVKRLLPECFT----FADREVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATL 559
+V +RL PE RE +LR+ H H++ + F ++ +L L
Sbjct: 56 EVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGEL 115
Query: 560 QDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMI 619
DY+ +K+ K ++ I+R +S LH+ +IVHRD+KP N+LL ++ +
Sbjct: 116 FDYLTEKVALSEK-ETRSIMRSLLEAVSFLHANNIVHRDLKPENILLD-----DNMQIRL 169
Query: 620 SDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTT------SIDIFSLGCVFYY 673
SDFG S L G + + GT G++APE++ T +D+++ G + +
Sbjct: 170 SDFGFSCHLEPG----EKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFT 225
Query: 674 VLSKGQHPFGDVLRRQ----ANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSAR 729
+L+ G PF RRQ I+ G Y + ++ +K LI ++ P AR
Sbjct: 226 LLA-GSPPFWH--RRQILMLRMIMEGQYQFSSPEW---DDRSSTVKDLISRLLQVDPEAR 279
Query: 730 PPCETILKYPMF 741
E L++P F
Sbjct: 280 LTAEQALQHPFF 291
>M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase
protein.
Length = 406
Score = 81.0 bits (191), Expect = 2e-14
Identities = 69/252 (27%), Positives = 116/252 (46%), Gaps = 31/252 (12%)
Query: 505 DVAVKRLLPECFT----FADREVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATL 559
+V +RL PE RE +LR+ H H++ + F ++ +L L
Sbjct: 56 EVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGEL 115
Query: 560 QDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMI 619
DY+ +K+ K ++ I+R +S LH+ +IVHRD+KP N+LL ++ +
Sbjct: 116 FDYLTEKVALSEK-ETRSIMRSLLEAVSFLHANNIVHRDLKPENILLD-----DNMQIRL 169
Query: 620 SDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTT------SIDIFSLGCVFYY 673
SDFG S L G + + GT G++APE++ T +D+++ G + +
Sbjct: 170 SDFGFSCHLEPG----EKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFT 225
Query: 674 VLSKGQHPFGDVLRRQ----ANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSAR 729
+L+ G PF RRQ I+ G Y + ++ +K LI ++ P AR
Sbjct: 226 LLA-GSPPFWH--RRQILMLRMIMEGQYQFSSPEW---DDRSSTVKDLISRLLQVDPEAR 279
Query: 730 PPCETILKYPMF 741
E L++P F
Sbjct: 280 LTAEQALQHPFF 291
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 81.0 bits (191), Expect = 2e-14
Identities = 79/274 (28%), Positives = 124/274 (45%), Gaps = 26/274 (9%)
Query: 481 FQTDQVLGKGCEGT-FVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ + LGKG G ++ R K +A+K L A E L RE + +H
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 535 VVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++R Y D Y+ LE T+ ++K F+ + + I A LS+ HS
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN-ALSYCHSKR 251
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
++HRD+KP N+LL GE++ I+DFG S SRR+ + GT ++ PEMI
Sbjct: 252 VIHRDIKPENLLLG---SAGELK--IADFGWSV-----HAPSSRRTTLCGTLDYLPPEMI 301
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY-NLDHLDKILPEEELV 712
G +D++SLG + Y L G+ PF +AN Y + ++ P+
Sbjct: 302 EGRMHDEKVDLWSLGVLCYEFL-VGKPPF------EANTYQETYKRISRVEFTFPDFVTE 354
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQS 746
+ LI ++ PS RP +L++P S
Sbjct: 355 GARDLISRLLKHNPSQRPMLREVLEHPWITANSS 388
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 81.0 bits (191), Expect = 2e-14
Identities = 79/274 (28%), Positives = 124/274 (45%), Gaps = 26/274 (9%)
Query: 481 FQTDQVLGKGCEGT-FVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ + LGKG G ++ R K +A+K L A E L RE + +H
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 535 VVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++R Y D Y+ LE T+ ++K F+ + + I A LS+ HS
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN-ALSYCHSKR 251
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
++HRD+KP N+LL GE++ I+DFG S SRR+ + GT ++ PEMI
Sbjct: 252 VIHRDIKPENLLLG---SAGELK--IADFGWSV-----HAPSSRRTTLCGTLDYLPPEMI 301
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY-NLDHLDKILPEEELV 712
G +D++SLG + Y L G+ PF +AN Y + ++ P+
Sbjct: 302 EGRMHDEKVDLWSLGVLCYEFL-VGKPPF------EANTYQETYKRISRVEFTFPDFVTE 354
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQS 746
+ LI ++ PS RP +L++P S
Sbjct: 355 GARDLISRLLKHNPSQRPMLREVLEHPWITANSS 388
>BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase,
gamma 2 (testis) protein.
Length = 406
Score = 81.0 bits (191), Expect = 2e-14
Identities = 69/252 (27%), Positives = 116/252 (46%), Gaps = 31/252 (12%)
Query: 505 DVAVKRLLPECFT----FADREVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATL 559
+V +RL PE RE +LR+ H H++ + F ++ +L L
Sbjct: 56 EVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGEL 115
Query: 560 QDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMI 619
DY+ +K+ K ++ I+R +S LH+ +IVHRD+KP N+LL ++ +
Sbjct: 116 FDYLTEKVALSEK-ETRSIMRSLLEAVSFLHANNIVHRDLKPENILLD-----DNMQIRL 169
Query: 620 SDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTT------SIDIFSLGCVFYY 673
SDFG S L G + + GT G++APE++ T +D+++ G + +
Sbjct: 170 SDFGFSCHLEPG----EKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFT 225
Query: 674 VLSKGQHPFGDVLRRQ----ANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSAR 729
+L+ G PF RRQ I+ G Y + ++ +K LI ++ P AR
Sbjct: 226 LLA-GSPPFWH--RRQILMLRMIMEGQYQFSSPEW---DDRSSTVKDLISRLLQVDPEAR 279
Query: 730 PPCETILKYPMF 741
E L++P F
Sbjct: 280 LTAEQALQHPFF 291
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 81.0 bits (191), Expect = 2e-14
Identities = 79/274 (28%), Positives = 124/274 (45%), Gaps = 26/274 (9%)
Query: 481 FQTDQVLGKGCEGT-FVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ + LGKG G ++ R K +A+K L A E L RE + +H
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 535 VVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++R Y D Y+ LE T+ ++K F+ + + I A LS+ HS
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN-ALSYCHSKR 251
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
++HRD+KP N+LL GE++ I+DFG S SRR+ + GT ++ PEMI
Sbjct: 252 VIHRDIKPENLLLG---SAGELK--IADFGWSV-----HAPSSRRTTLCGTLDYLPPEMI 301
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY-NLDHLDKILPEEELV 712
G +D++SLG + Y L G+ PF +AN Y + ++ P+
Sbjct: 302 EGRMHDEKVDLWSLGVLCYEFL-VGKPPF------EANTYQETYKRISRVEFTFPDFVTE 354
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQS 746
+ LI ++ PS RP +L++P S
Sbjct: 355 GARDLISRLLKHNPSQRPMLREVLEHPWITANSS 388
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 81.0 bits (191), Expect = 2e-14
Identities = 79/274 (28%), Positives = 124/274 (45%), Gaps = 26/274 (9%)
Query: 481 FQTDQVLGKGCEGT-FVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ + LGKG G ++ R K +A+K L A E L RE + +H
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 535 VVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++R Y D Y+ LE T+ ++K F+ + + I A LS+ HS
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN-ALSYCHSKR 251
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
++HRD+KP N+LL GE++ I+DFG S SRR+ + GT ++ PEMI
Sbjct: 252 VIHRDIKPENLLLG---SAGELK--IADFGWSV-----HAPSSRRTTLCGTLDYLPPEMI 301
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY-NLDHLDKILPEEELV 712
G +D++SLG + Y L G+ PF +AN Y + ++ P+
Sbjct: 302 EGRMHDEKVDLWSLGVLCYEFL-VGKPPF------EANTYQETYKRISRVEFTFPDFVTE 354
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQS 746
+ LI ++ PS RP +L++P S
Sbjct: 355 GARDLISRLLKHNPSQRPMLREVLEHPWITANSS 388
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 81.0 bits (191), Expect = 2e-14
Identities = 79/274 (28%), Positives = 124/274 (45%), Gaps = 26/274 (9%)
Query: 481 FQTDQVLGKGCEGT-FVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ + LGKG G ++ R K +A+K L A E L RE + +H
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 535 VVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++R Y D Y+ LE T+ ++K F+ + + I A LS+ HS
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN-ALSYCHSKR 251
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
++HRD+KP N+LL GE++ I+DFG S SRR+ + GT ++ PEMI
Sbjct: 252 VIHRDIKPENLLLG---SAGELK--IADFGWSV-----HAPSSRRTTLCGTLDYLPPEMI 301
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY-NLDHLDKILPEEELV 712
G +D++SLG + Y L G+ PF +AN Y + ++ P+
Sbjct: 302 EGRMHDEKVDLWSLGVLCYEFL-VGKPPF------EANTYQETYKRISRVEFTFPDFVTE 354
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQS 746
+ LI ++ PS RP +L++P S
Sbjct: 355 GARDLISRLLKHNPSQRPMLREVLEHPWITANSS 388
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 81.0 bits (191), Expect = 2e-14
Identities = 79/274 (28%), Positives = 124/274 (45%), Gaps = 26/274 (9%)
Query: 481 FQTDQVLGKGCEGT-FVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ + LGKG G ++ R K +A+K L A E L RE + +H
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 535 VVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++R Y D Y+ LE T+ ++K F+ + + I A LS+ HS
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN-ALSYCHSKR 251
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
++HRD+KP N+LL GE++ I+DFG S SRR+ + GT ++ PEMI
Sbjct: 252 VIHRDIKPENLLLG---SAGELK--IADFGWSV-----HAPSSRRTTLCGTLDYLPPEMI 301
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY-NLDHLDKILPEEELV 712
G +D++SLG + Y L G+ PF +AN Y + ++ P+
Sbjct: 302 EGRMHDEKVDLWSLGVLCYEFL-VGKPPF------EANTYQETYKRISRVEFTFPDFVTE 354
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQS 746
+ LI ++ PS RP +L++P S
Sbjct: 355 GARDLISRLLKHNPSQRPMLREVLEHPWITANSS 388
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 81.0 bits (191), Expect = 2e-14
Identities = 79/274 (28%), Positives = 124/274 (45%), Gaps = 26/274 (9%)
Query: 481 FQTDQVLGKGCEGT-FVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ + LGKG G ++ R K +A+K L A E L RE + +H
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 535 VVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++R Y D Y+ LE T+ ++K F+ + + I A LS+ HS
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN-ALSYCHSKR 251
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
++HRD+KP N+LL GE++ I+DFG S SRR+ + GT ++ PEMI
Sbjct: 252 VIHRDIKPENLLLG---SAGELK--IADFGWSV-----HAPSSRRTTLCGTLDYLPPEMI 301
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY-NLDHLDKILPEEELV 712
G +D++SLG + Y L G+ PF +AN Y + ++ P+
Sbjct: 302 EGRMHDEKVDLWSLGVLCYEFL-VGKPPF------EANTYQETYKRISRVEFTFPDFVTE 354
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQS 746
+ LI ++ PS RP +L++P S
Sbjct: 355 GARDLISRLLKHNPSQRPMLREVLEHPWITANSS 388
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 81.0 bits (191), Expect = 2e-14
Identities = 79/274 (28%), Positives = 124/274 (45%), Gaps = 26/274 (9%)
Query: 481 FQTDQVLGKGCEGT-FVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ + LGKG G ++ R K +A+K L A E L RE + +H
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 535 VVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++R Y D Y+ LE T+ ++K F+ + + I A LS+ HS
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN-ALSYCHSKR 251
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
++HRD+KP N+LL GE++ I+DFG S SRR+ + GT ++ PEMI
Sbjct: 252 VIHRDIKPENLLLG---SAGELK--IADFGWSV-----HAPSSRRTTLCGTLDYLPPEMI 301
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY-NLDHLDKILPEEELV 712
G +D++SLG + Y L G+ PF +AN Y + ++ P+
Sbjct: 302 EGRMHDEKVDLWSLGVLCYEFL-VGKPPF------EANTYQETYKRISRVEFTFPDFVTE 354
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQS 746
+ LI ++ PS RP +L++P S
Sbjct: 355 GARDLISRLLKHNPSQRPMLREVLEHPWITANSS 388
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 80.6 bits (190), Expect = 2e-14
Identities = 77/274 (28%), Positives = 124/274 (45%), Gaps = 26/274 (9%)
Query: 481 FQTDQVLGKGCEGT-FVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ + LGKG G ++ R K +A+K L A E L RE + +H
Sbjct: 132 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 191
Query: 535 VVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++R Y D Y+ LE T+ ++K F+ + + + + LS+ HS
Sbjct: 192 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFD-EQRTANLYNRIANALSYCHSKR 250
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
++HRD+KP N+LL GE++ I+DFG S SRR+ + GT ++ PEMI
Sbjct: 251 VIHRDIKPENLLLG---SAGELK--IADFGWSV-----HAPSSRRTTLCGTLDYLPPEMI 300
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY-NLDHLDKILPEEELV 712
G +D++SLG + Y L G+ PF +AN Y + ++ P+
Sbjct: 301 EGRMHDEKVDLWSLGVLCYEFL-VGKPPF------EANTYQETYKRISRVEFTFPDFVTE 353
Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQS 746
+ LI ++ PS RP +L++P S
Sbjct: 354 GARDLISRLLKHNPSQRPMLREVLEHPWITANSS 387
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 80.2 bits (189), Expect = 3e-14
Identities = 71/226 (31%), Positives = 112/226 (49%), Gaps = 23/226 (10%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+RE+A+L+ + H HV++ + +K++ Y+ LE S L DY+ KK K ++ +
Sbjct: 16 EREIAILKLIE-HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK-EARKF 73
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
RQ L HS I HRD+KP N+LL + +R I+DFG++ L +G S
Sbjct: 74 FRQIVSALDFCHSYSICHRDLKPENLLLDEKN---NIR--IADFGMA-SLQVGD---SLL 124
Query: 639 SGVTGTDGWIAPEMINGER-TTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTG 695
G+ + PE+I GE+ D++S G V + L G PF D RQ + G
Sbjct: 125 ETSCGSPHYACPEVIKGEKYDGRRADMWSCG-VILFALLVGALPFDDDNLRQLLEKVKRG 183
Query: 696 DYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+++ H I P+ + L+R MI +P R E I K+P +
Sbjct: 184 VFHMPHF--IPPD-----CQSLLRGMIEVEPEKRLSLEQIQKHPWY 222
>CR542225-1|CAG47021.1| 372|Homo sapiens STK17B protein.
Length = 372
Score = 79.8 bits (188), Expect = 4e-14
Identities = 49/172 (28%), Positives = 91/172 (52%), Gaps = 10/172 (5%)
Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633
D + +++Q G+ +LH +IVH D+KP N+LLS G+++ I DFG+S+K IG
Sbjct: 134 DVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIK--IVDFGMSRK--IGHA 189
Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANIL 693
R + GT ++APE++N + TT+ D++++G + Y +L+ PF ++ +
Sbjct: 190 CELRE--IMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTH-TSPFVGEDNQETYLN 246
Query: 694 TGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQ 745
N+D+ ++ + I++++ P RP E L + W +Q
Sbjct: 247 ISQVNVDYSEETFSSVSQLATD-FIQSLLVKNPEKRPTAEICLSHS--WLQQ 295
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 79.8 bits (188), Expect = 4e-14
Identities = 71/290 (24%), Positives = 130/290 (44%), Gaps = 26/290 (8%)
Query: 481 FQTDQVLGKGC-EGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ +LGKG G + +VA+K + + A + E H
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71
Query: 535 VVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++ Y D + Y+ LE+C + + Y++ ++ + ++ + Q G+ +LHS
Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG 131
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+ N+LL T + I+DFGL+ +L ++ + + GT +I+PE+
Sbjct: 132 ILHRDLTLSNLLL-----TRNMNIKIADFGLATQL---KMPHEKHYTLCGTPNYISPEIA 183
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFG-DVLRRQAN-ILTGDYNLDHLDKILPEEEL 711
D++SLGC+FY +L G+ PF D ++ N ++ DY +P
Sbjct: 184 TRSAHGLESDVWSLGCMFYTLLI-GRPPFDTDTVKNTLNKVVLADYE-------MPSFLS 235
Query: 712 VVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILN-FLQDVSDQVES 760
+ K LI ++ P+ R ++L +P S + L V D ++S
Sbjct: 236 IEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDS 285
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 79.8 bits (188), Expect = 4e-14
Identities = 71/290 (24%), Positives = 130/290 (44%), Gaps = 26/290 (8%)
Query: 481 FQTDQVLGKGC-EGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ +LGKG G + +VA+K + + A + E H
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71
Query: 535 VVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++ Y D + Y+ LE+C + + Y++ ++ + ++ + Q G+ +LHS
Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG 131
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+ N+LL T + I+DFGL+ +L ++ + + GT +I+PE+
Sbjct: 132 ILHRDLTLSNLLL-----TRNMNIKIADFGLATQL---KMPHEKHYTLCGTPNYISPEIA 183
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFG-DVLRRQAN-ILTGDYNLDHLDKILPEEEL 711
D++SLGC+FY +L G+ PF D ++ N ++ DY +P
Sbjct: 184 TRSAHGLESDVWSLGCMFYTLLI-GRPPFDTDTVKNTLNKVVLADYE-------MPTFLS 235
Query: 712 VVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILN-FLQDVSDQVES 760
+ K LI ++ P+ R ++L +P S + L V D ++S
Sbjct: 236 IEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDS 285
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 79.4 bits (187), Expect = 6e-14
Identities = 71/290 (24%), Positives = 130/290 (44%), Gaps = 26/290 (8%)
Query: 481 FQTDQVLGKGC-EGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ +LGKG G + +VA+K + + A + E H
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKHPS 71
Query: 535 VVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++ Y D + Y+ LE+C + + Y++ ++ + ++ + Q G+ +LHS
Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG 131
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+ N+LL T + I+DFGL+ +L ++ + + GT +I+PE+
Sbjct: 132 ILHRDLTLSNLLL-----TRNMNIKIADFGLATQL---KMPHEKHYTLCGTPNYISPEIA 183
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFG-DVLRRQAN-ILTGDYNLDHLDKILPEEEL 711
D++SLGC+FY +L G+ PF D ++ N ++ DY +P
Sbjct: 184 TRSAHGLESDVWSLGCMFYTLLI-GRPPFDTDTVKNTLNKVVLADYE-------MPTFLS 235
Query: 712 VVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILN-FLQDVSDQVES 760
+ K LI ++ P+ R ++L +P S + L V D ++S
Sbjct: 236 IEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDS 285
>BC016040-1|AAH16040.1| 372|Homo sapiens serine/threonine kinase
17b protein.
Length = 372
Score = 79.4 bits (187), Expect = 6e-14
Identities = 49/172 (28%), Positives = 91/172 (52%), Gaps = 10/172 (5%)
Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633
D + +++Q G+ +LH +IVH D+KP N+LLS G+++ I DFG+S+K IG
Sbjct: 134 DVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIK--IVDFGMSRK--IGHA 189
Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANIL 693
R + GT ++APE++N + TT+ D++++G + Y +L+ PF ++ +
Sbjct: 190 CELRE--IMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTH-TSPFVGEDNQETYLN 246
Query: 694 TGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQ 745
N+D+ ++ + I++++ P RP E L + W +Q
Sbjct: 247 ISQVNVDYSEETFSSVSQLATD-FIQSLLVKNPEKRPTAEICLSHS--WLQQ 295
>AC114760-2|AAY14982.1| 372|Homo sapiens unknown protein.
Length = 372
Score = 79.4 bits (187), Expect = 6e-14
Identities = 49/172 (28%), Positives = 91/172 (52%), Gaps = 10/172 (5%)
Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633
D + +++Q G+ +LH +IVH D+KP N+LLS G+++ I DFG+S+K IG
Sbjct: 134 DVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIK--IVDFGMSRK--IGHA 189
Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANIL 693
R + GT ++APE++N + TT+ D++++G + Y +L+ PF ++ +
Sbjct: 190 CELRE--IMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTH-TSPFVGEDNQETYLN 246
Query: 694 TGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQ 745
N+D+ ++ + I++++ P RP E L + W +Q
Sbjct: 247 ISQVNVDYSEETFSSVSQLATD-FIQSLLVKNPEKRPTAEICLSHS--WLQQ 295
>AB011421-1|BAA34127.1| 372|Homo sapiens DRAK2 protein.
Length = 372
Score = 79.4 bits (187), Expect = 6e-14
Identities = 49/172 (28%), Positives = 91/172 (52%), Gaps = 10/172 (5%)
Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633
D + +++Q G+ +LH +IVH D+KP N+LLS G+++ I DFG+S+K IG
Sbjct: 134 DVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIK--IVDFGMSRK--IGHA 189
Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANIL 693
R + GT ++APE++N + TT+ D++++G + Y +L+ PF ++ +
Sbjct: 190 CELRE--IMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTH-TSPFVGEDNQETYLN 246
Query: 694 TGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQ 745
N+D+ ++ + I++++ P RP E L + W +Q
Sbjct: 247 ISQVNVDYSEETFSSVSQLATD-FIQSLLVKNPEKRPTAEICLSHS--WLQQ 295
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 79.0 bits (186), Expect = 8e-14
Identities = 69/263 (26%), Positives = 122/263 (46%), Gaps = 21/263 (7%)
Query: 485 QVLGKGCEG-TFVYRGTFDKRDVAVKRLLPECFTFADREVA----LLRESDAHAHVVRYY 539
+ +G+G G ++ +G D + +K + E ++E + +L E H ++V ++
Sbjct: 8 KAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPNIVAFF 67
Query: 540 CTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSV-EILRQATMGLSHLHSMDIVHR 597
+ ++ +I +E C L + ++ D + Q ++GL H+H I+HR
Sbjct: 68 NSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHR 127
Query: 598 DVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGER 657
D+K N+ LS G V A + DFG+++ LN + +R GT +++PE+ +
Sbjct: 128 DIKAQNIFLSK---NGMV-AKLGDFGIARVLN-NSMELART--CIGTPYYLSPEICQNKP 180
Query: 658 TTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQANILTGDYNLDHLDKILPEEELVVIKI 716
DI+SLGCV Y + + +HPF G+ L++ L H I P +
Sbjct: 181 YNNKTDIWSLGCVLYELCTL-KHPFEGNNLQQ----LVLKICQAHFAPISPGFSR-ELHS 234
Query: 717 LIRAMISAKPSARPPCETILKYP 739
LI + P RP +ILK P
Sbjct: 235 LISQLFQVSPRDRPSINSILKRP 257
>BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H1
protein.
Length = 424
Score = 79.0 bits (186), Expect = 8e-14
Identities = 65/223 (29%), Positives = 116/223 (52%), Gaps = 13/223 (5%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+ +LR HA++++ ++ Y+ +EL + L D + K +F + D+ +
Sbjct: 141 ESELRVLRRV-RHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTER-DATRV 198
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+ G+ +LH++ I HRD+KP N+L P GT + + +I+DFGL+ G +
Sbjct: 199 LQMVLDGVRYLHALGITHRDLKPENLLYYHP-GT-DSKIIITDFGLASARKKGDDCLMKT 256
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGD 696
+ GT +IAPE++ + T S+D+++LG + Y +LS G PF D R + IL G
Sbjct: 257 T--CGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLS-GTMPFEDDNRTRLYRQILRGK 313
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y+ + + P + K I +++ P AR L++P
Sbjct: 314 YS--YSGEPWPSVSNLA-KDFIDRLLTVDPGARMTALQALRHP 353
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 79.0 bits (186), Expect = 8e-14
Identities = 69/263 (26%), Positives = 122/263 (46%), Gaps = 21/263 (7%)
Query: 485 QVLGKGCEG-TFVYRGTFDKRDVAVKRLLPECFTFADREVA----LLRESDAHAHVVRYY 539
+ +G+G G ++ +G D + +K + E ++E + +L E H ++V ++
Sbjct: 8 KAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPNIVAFF 67
Query: 540 CTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSV-EILRQATMGLSHLHSMDIVHR 597
+ ++ +I +E C L + ++ D + Q ++GL H+H I+HR
Sbjct: 68 NSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHR 127
Query: 598 DVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGER 657
D+K N+ LS G V A + DFG+++ LN + +R GT +++PE+ +
Sbjct: 128 DIKAQNIFLSK---NGMV-AKLGDFGIARVLN-NSMELART--CIGTPYYLSPEICQNKP 180
Query: 658 TTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQANILTGDYNLDHLDKILPEEELVVIKI 716
DI+SLGCV Y + + +HPF G+ L++ L H I P +
Sbjct: 181 YNNKTDIWSLGCVLYELCTL-KHPFEGNNLQQ----LVLKICQAHFAPISPGFSR-ELHS 234
Query: 717 LIRAMISAKPSARPPCETILKYP 739
LI + P RP +ILK P
Sbjct: 235 LISQLFQVSPRDRPSINSILKRP 257
>AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase
protein.
Length = 424
Score = 79.0 bits (186), Expect = 8e-14
Identities = 65/223 (29%), Positives = 116/223 (52%), Gaps = 13/223 (5%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+ +LR HA++++ ++ Y+ +EL + L D + K +F + D+ +
Sbjct: 141 ESELRVLRRV-RHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTER-DATRV 198
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+ G+ +LH++ I HRD+KP N+L P GT + + +I+DFGL+ G +
Sbjct: 199 LQMVLDGVRYLHALGITHRDLKPENLLYYHP-GT-DSKIIITDFGLASARKKGDDCLMKT 256
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGD 696
+ GT +IAPE++ + T S+D+++LG + Y +LS G PF D R + IL G
Sbjct: 257 T--CGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLS-GTMPFEDDNRTRLYRQILRGK 313
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y+ + + P + K I +++ P AR L++P
Sbjct: 314 YS--YSGEPWPSVSNLA-KDFIDRLLTVDPGARMTALQALRHP 353
>L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13
protein.
Length = 676
Score = 78.6 bits (185), Expect = 1e-13
Identities = 74/229 (32%), Positives = 108/229 (47%), Gaps = 25/229 (10%)
Query: 468 EIGEGEMKIGKITFQTDQVLGKGCEGTFVY-----RGTFD-----KRDVAVKRLLPECFT 517
+I EG K F +VLGKG G + RG + K+DV + EC
Sbjct: 336 KIWEGSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTM 395
Query: 518 FADREVALLRESDAHAHVVRYYCTERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSV 576
R + L E+ H++ CT + K + +E L L +++ K FE +
Sbjct: 396 VEKRVLTLAAENPFLTHLI---CTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFEL-YRAT 451
Query: 577 EILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS 636
+ GL LHS I++RD+K NVLL G ++ I+DFG+ K+ G S
Sbjct: 452 FYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRD---GHIK--IADFGMCKENIFGE---S 503
Query: 637 RRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GD 684
R S GT +IAPE++ G + T S+D +S G + Y +L GQ PF GD
Sbjct: 504 RASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLI-GQSPFHGD 551
>BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase
17a protein.
Length = 414
Score = 78.6 bits (185), Expect = 1e-13
Identities = 58/178 (32%), Positives = 93/178 (52%), Gaps = 20/178 (11%)
Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633
D ++RQ G+ LH+ D+VH D+KP N+LL+ S G+++ I DFGLS+ L
Sbjct: 162 DVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIK--IVDFGLSRILK---- 215
Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQANI 692
+ + GT ++APE+++ + + + D++S+G V YV+ G PF G+ +Q
Sbjct: 216 NSEELREIMGTPEYVAPEILSYDPISMATDMWSIG-VLTYVMLTGISPFLGN--DKQETF 272
Query: 693 LTGDYNLDHLDKILPEEELVVIK----ILIRAMISAKPSARPPCETILKYPMFWCKQS 746
L N+ ++ EEE V+ IR ++ KP R E LK+P W QS
Sbjct: 273 L----NISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHP--WLTQS 324
>BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase
17a protein.
Length = 414
Score = 78.6 bits (185), Expect = 1e-13
Identities = 58/178 (32%), Positives = 93/178 (52%), Gaps = 20/178 (11%)
Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633
D ++RQ G+ LH+ D+VH D+KP N+LL+ S G+++ I DFGLS+ L
Sbjct: 162 DVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIK--IVDFGLSRILK---- 215
Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQANI 692
+ + GT ++APE+++ + + + D++S+G V YV+ G PF G+ +Q
Sbjct: 216 NSEELREIMGTPEYVAPEILSYDPISMATDMWSIG-VLTYVMLTGISPFLGN--DKQETF 272
Query: 693 LTGDYNLDHLDKILPEEELVVIK----ILIRAMISAKPSARPPCETILKYPMFWCKQS 746
L N+ ++ EEE V+ IR ++ KP R E LK+P W QS
Sbjct: 273 L----NISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHP--WLTQS 324
>AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein.
Length = 414
Score = 78.6 bits (185), Expect = 1e-13
Identities = 58/178 (32%), Positives = 93/178 (52%), Gaps = 20/178 (11%)
Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633
D ++RQ G+ LH+ D+VH D+KP N+LL+ S G+++ I DFGLS+ L
Sbjct: 162 DVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIK--IVDFGLSRILK---- 215
Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQANI 692
+ + GT ++APE+++ + + + D++S+G V YV+ G PF G+ +Q
Sbjct: 216 NSEELREIMGTPEYVAPEILSYDPISMATDMWSIG-VLTYVMLTGISPFLGN--DKQETF 272
Query: 693 LTGDYNLDHLDKILPEEELVVIK----ILIRAMISAKPSARPPCETILKYPMFWCKQS 746
L N+ ++ EEE V+ IR ++ KP R E LK+P W QS
Sbjct: 273 L----NISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHP--WLTQS 324
>BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein.
Length = 363
Score = 78.2 bits (184), Expect = 1e-13
Identities = 69/210 (32%), Positives = 107/210 (50%), Gaps = 19/210 (9%)
Query: 484 DQVLGKGCEGTFVYRGTFDK--RDVAVK-----RLLPECFTFADREVALLRESDAHAHVV 536
D+VLG G G VY G K RDVAVK R + + EVA+L +S H +V
Sbjct: 39 DEVLGSGQFGV-VYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAIL-QSLRHPGIV 96
Query: 537 RYYCTERDKQFRYIALELCSATLQDYV--EKKLNFECKIDSVEILRQATMGLSHLHSMDI 594
C + ++ +E + + + +K ++ ++ Q + L HLH +I
Sbjct: 97 NLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKF-LITQILVALRHLHFKNI 155
Query: 595 VHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN 654
VH D+KP NVLL+ +V+ + DFG ++ IG SF RRS V GT ++APE++
Sbjct: 156 VHCDLKPENVLLASADPFPQVK--LCDFGFAR--IIGEKSF-RRS-VVGTPAYLAPEVLL 209
Query: 655 GERTTTSIDIFSLGCVFYYVLSKGQHPFGD 684
+ S+D++S+G + Y LS G PF +
Sbjct: 210 NQGYNRSLDMWSVGVIMYVSLS-GTFPFNE 238
>AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ90785 fis, clone THYRO1001457, moderately
similar to H.sapiens mRNA for protein kinase C mu. ).
Length = 721
Score = 78.2 bits (184), Expect = 1e-13
Identities = 69/210 (32%), Positives = 107/210 (50%), Gaps = 19/210 (9%)
Query: 484 DQVLGKGCEGTFVYRGTFDK--RDVAVK-----RLLPECFTFADREVALLRESDAHAHVV 536
D+VLG G G VY G K RDVAVK R + + EVA+L +S H +V
Sbjct: 397 DEVLGSGQFGV-VYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAIL-QSLRHPGIV 454
Query: 537 RYYCTERDKQFRYIALELCSATLQDYV--EKKLNFECKIDSVEILRQATMGLSHLHSMDI 594
C + ++ +E + + + +K ++ ++ Q + L HLH +I
Sbjct: 455 NLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKF-LITQILVALRHLHFKNI 513
Query: 595 VHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN 654
VH D+KP NVLL+ +V+ + DFG ++ IG SF RRS V GT ++APE++
Sbjct: 514 VHCDLKPENVLLASADPFPQVK--LCDFGFAR--IIGEKSF-RRS-VVGTPAYLAPEVLL 567
Query: 655 GERTTTSIDIFSLGCVFYYVLSKGQHPFGD 684
+ S+D++S+G + Y LS G PF +
Sbjct: 568 NQGYNRSLDMWSVGVIMYVSLS-GTFPFNE 596
>AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ90192 fis, clone MAMMA1001150, moderately
similar to PROTEIN KINASE C, MU TYPE (EC 2.7.1.-). ).
Length = 721
Score = 78.2 bits (184), Expect = 1e-13
Identities = 69/210 (32%), Positives = 107/210 (50%), Gaps = 19/210 (9%)
Query: 484 DQVLGKGCEGTFVYRGTFDK--RDVAVK-----RLLPECFTFADREVALLRESDAHAHVV 536
D+VLG G G VY G K RDVAVK R + + EVA+L +S H +V
Sbjct: 397 DEVLGSGQFGV-VYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAIL-QSLRHPGIV 454
Query: 537 RYYCTERDKQFRYIALELCSATLQDYV--EKKLNFECKIDSVEILRQATMGLSHLHSMDI 594
C + ++ +E + + + +K ++ ++ Q + L HLH +I
Sbjct: 455 NLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKF-LITQILVALRHLHFKNI 513
Query: 595 VHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN 654
VH D+KP NVLL+ +V+ + DFG ++ IG SF RRS V GT ++APE++
Sbjct: 514 VHCDLKPENVLLASADPFPQVK--LCDFGFAR--IIGEKSF-RRS-VVGTPAYLAPEVLL 567
Query: 655 GERTTTSIDIFSLGCVFYYVLSKGQHPFGD 684
+ S+D++S+G + Y LS G PF +
Sbjct: 568 NQGYNRSLDMWSVGVIMYVSLS-GTFPFNE 596
>AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein.
Length = 878
Score = 78.2 bits (184), Expect = 1e-13
Identities = 69/210 (32%), Positives = 107/210 (50%), Gaps = 19/210 (9%)
Query: 484 DQVLGKGCEGTFVYRGTFDK--RDVAVK-----RLLPECFTFADREVALLRESDAHAHVV 536
D+VLG G G VY G K RDVAVK R + + EVA+L +S H +V
Sbjct: 554 DEVLGSGQFGV-VYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAIL-QSLRHPGIV 611
Query: 537 RYYCTERDKQFRYIALELCSATLQDYV--EKKLNFECKIDSVEILRQATMGLSHLHSMDI 594
C + ++ +E + + + +K ++ ++ Q + L HLH +I
Sbjct: 612 NLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKF-LITQILVALRHLHFKNI 670
Query: 595 VHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN 654
VH D+KP NVLL+ +V+ + DFG ++ IG SF RRS V GT ++APE++
Sbjct: 671 VHCDLKPENVLLASADPFPQVK--LCDFGFAR--IIGEKSF-RRS-VVGTPAYLAPEVLL 724
Query: 655 GERTTTSIDIFSLGCVFYYVLSKGQHPFGD 684
+ S+D++S+G + Y LS G PF +
Sbjct: 725 NQGYNRSLDMWSVGVIMYVSLS-GTFPFNE 753
>BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 77.8 bits (183), Expect = 2e-13
Identities = 77/278 (27%), Positives = 138/278 (49%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ +V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-PYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D +E E +I + ILR+ GL +LHS +HRD+
Sbjct: 88 SYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIAT--ILREILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S GEV+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEHGEVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIKQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L++G+ P ++ + L N L+ + +K +
Sbjct: 198 SKADIWSLG-ITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKP----LKEFVE 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ +PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR 290
>BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 77.8 bits (183), Expect = 2e-13
Identities = 61/213 (28%), Positives = 107/213 (50%), Gaps = 14/213 (6%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV +LRE H +++ + +K + LEL S L D++ +K + + ++ +
Sbjct: 62 EREVNILREI-RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLT-EDEATQF 119
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+Q G+ +LHS I H D+KP N++L + R + DFG++ K+ G +
Sbjct: 120 LKQILDGVHYLHSKRIAHFDLKPENIML-LDKNVPNPRIKLIDFGIAHKIEAG----NEF 174
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF +++ NI +
Sbjct: 175 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGETKQETLTNISAVN 233
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSAR 729
Y+ D + EL K IR ++ P R
Sbjct: 234 YDFDE-EYFSNTSELA--KDFIRRLLVKDPKRR 263
>BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 77.8 bits (183), Expect = 2e-13
Identities = 61/213 (28%), Positives = 107/213 (50%), Gaps = 14/213 (6%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV +LRE H +++ + +K + LEL S L D++ +K + + ++ +
Sbjct: 62 EREVNILREI-RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLT-EDEATQF 119
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+Q G+ +LHS I H D+KP N++L + R + DFG++ K+ G +
Sbjct: 120 LKQILDGVHYLHSKRIAHFDLKPENIML-LDKNVPNPRIKLIDFGIAHKIEAG----NEF 174
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF +++ NI +
Sbjct: 175 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGETKQETLTNISAVN 233
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSAR 729
Y+ D + EL K IR ++ P R
Sbjct: 234 YDFDE-EYFSNTSELA--KDFIRRLLVKDPKRR 263
>BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 77.8 bits (183), Expect = 2e-13
Identities = 77/278 (27%), Positives = 138/278 (49%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ +V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-PYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D +E E +I + ILR+ GL +LHS +HRD+
Sbjct: 88 SYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIAT--ILREILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S GEV+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEHGEVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIKQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L++G+ P ++ + L N L+ + +K +
Sbjct: 198 SKADIWSLG-ITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKP----LKEFVE 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ +PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR 290
>BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 77.8 bits (183), Expect = 2e-13
Identities = 77/278 (27%), Positives = 138/278 (49%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ +V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-PYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D +E E +I + ILR+ GL +LHS +HRD+
Sbjct: 88 SYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIAT--ILREILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S GEV+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEHGEVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIKQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L++G+ P ++ + L N L+ + +K +
Sbjct: 198 SKADIWSLG-ITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKP----LKEFVE 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ +PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR 290
>AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 77.8 bits (183), Expect = 2e-13
Identities = 77/278 (27%), Positives = 138/278 (49%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ +V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-PYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D +E E +I + ILR+ GL +LHS +HRD+
Sbjct: 88 SYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIAT--ILREILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S GEV+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEHGEVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIKQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L++G+ P ++ + L N L+ + +K +
Sbjct: 198 SKADIWSLG-ITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKP----LKEFVE 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ +PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR 290
>AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 77.8 bits (183), Expect = 2e-13
Identities = 77/278 (27%), Positives = 138/278 (49%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ +V +YY
Sbjct: 42 IGKGSFGE-VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-PYVTKYYG 99
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D +E E +I + ILR+ GL +LHS +HRD+
Sbjct: 100 SYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIAT--ILREILKGLDYLHSEKKIHRDI 157
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S GEV+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 158 KAANVLL---SEHGEVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIKQSAYD 209
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L++G+ P ++ + L N L+ + +K +
Sbjct: 210 SKADIWSLG-ITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKP----LKEFVE 264
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ +PS RP + +LK+ ++L ++ D+
Sbjct: 265 ACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR 302
>AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 77.8 bits (183), Expect = 2e-13
Identities = 77/278 (27%), Positives = 138/278 (49%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ +V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-PYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D +E E +I + ILR+ GL +LHS +HRD+
Sbjct: 88 SYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIAT--ILREILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S GEV+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEHGEVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIKQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L++G+ P ++ + L N L+ + +K +
Sbjct: 198 SKADIWSLG-ITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKP----LKEFVE 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ +PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR 290
>AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 77.8 bits (183), Expect = 2e-13
Identities = 77/278 (27%), Positives = 138/278 (49%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ +V +YY
Sbjct: 42 IGKGSFGE-VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-PYVTKYYG 99
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D +E E +I + ILR+ GL +LHS +HRD+
Sbjct: 100 SYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIAT--ILREILKGLDYLHSEKKIHRDI 157
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S GEV+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 158 KAANVLL---SEHGEVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIKQSAYD 209
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L++G+ P ++ + L N L+ + +K +
Sbjct: 210 SKADIWSLG-ITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKP----LKEFVE 264
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ +PS RP + +LK+ ++L ++ D+
Sbjct: 265 ACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR 302
>AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-like
protein kinase 3 protein.
Length = 443
Score = 77.8 bits (183), Expect = 2e-13
Identities = 77/278 (27%), Positives = 138/278 (49%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ +V +YY
Sbjct: 42 IGKGSFGE-VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-PYVTKYYG 99
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D +E E +I + ILR+ GL +LHS +HRD+
Sbjct: 100 SYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIAT--ILREILKGLDYLHSEKKIHRDI 157
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S GEV+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 158 KAANVLL---SEHGEVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIKQSAYD 209
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L++G+ P ++ + L N L+ + +K +
Sbjct: 210 SKADIWSLG-ITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKP----LKEFVE 264
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ +PS RP + +LK+ ++L ++ D+
Sbjct: 265 ACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR 302
>AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3
protein.
Length = 431
Score = 77.8 bits (183), Expect = 2e-13
Identities = 77/278 (27%), Positives = 138/278 (49%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ +V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-PYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D +E E +I + ILR+ GL +LHS +HRD+
Sbjct: 88 SYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIAT--ILREILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S GEV+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEHGEVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIKQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L++G+ P ++ + L N L+ + +K +
Sbjct: 198 SKADIWSLG-ITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKP----LKEFVE 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ +PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR 290
>AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein.
Length = 454
Score = 77.8 bits (183), Expect = 2e-13
Identities = 61/213 (28%), Positives = 107/213 (50%), Gaps = 14/213 (6%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV +LRE H +++ + +K + LEL S L D++ +K + + ++ +
Sbjct: 62 EREVNILREI-RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLT-EDEATQF 119
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+Q G+ +LHS I H D+KP N++L + R + DFG++ K+ G +
Sbjct: 120 LKQILDGVHYLHSKRIAHFDLKPENIML-LDKNVPNPRIKLIDFGIAHKIEAG----NEF 174
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF +++ NI +
Sbjct: 175 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGETKQETLTNISAVN 233
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSAR 729
Y+ D + EL K IR ++ P R
Sbjct: 234 YDFDE-EYFSNTSELA--KDFIRRLLVKDPKRR 263
>AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein.
Length = 454
Score = 77.8 bits (183), Expect = 2e-13
Identities = 61/213 (28%), Positives = 107/213 (50%), Gaps = 14/213 (6%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV +LRE H +++ + +K + LEL S L D++ +K + + ++ +
Sbjct: 62 EREVNILREI-RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLT-EDEATQF 119
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
L+Q G+ +LHS I H D+KP N++L + R + DFG++ K+ G +
Sbjct: 120 LKQILDGVHYLHSKRIAHFDLKPENIML-LDKNVPNPRIKLIDFGIAHKIEAG----NEF 174
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF +++ NI +
Sbjct: 175 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGETKQETLTNISAVN 233
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSAR 729
Y+ D + EL K IR ++ P R
Sbjct: 234 YDFDE-EYFSNTSELA--KDFIRRLLVKDPKRR 263
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 77.4 bits (182), Expect = 2e-13
Identities = 66/247 (26%), Positives = 118/247 (47%), Gaps = 19/247 (7%)
Query: 481 FQTDQVLGKGCEGTFVY-RGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----HAH 534
F+ ++LG+G T V R R+ A+K L ++ + RE D H
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 141
Query: 535 VVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V+ Y T +D + Y L + L Y+ K +F+ + + + L +LH
Sbjct: 142 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD-ETCTRFYTAEIVSALEYLHGKG 200
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+KP N+LL+ ++ I+DFG +K L+ +R + GT +++PE++
Sbjct: 201 IIHRDLKPENILLN-----EDMHIQITDFGTAKVLS-PESKQARANSFVGTAQYVSPELL 254
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEEL 711
+ S D+++LGC+ Y +++ G PF G+ I+ +Y D +K P+
Sbjct: 255 TEKSACKSSDLWALGCIIYQLVA-GLPPFRAGNEYLIFQKIIKLEY--DFPEKFFPKARD 311
Query: 712 VVIKILI 718
+V K+L+
Sbjct: 312 LVEKLLV 318
>X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein.
Length = 912
Score = 77.4 bits (182), Expect = 2e-13
Identities = 68/211 (32%), Positives = 105/211 (49%), Gaps = 21/211 (9%)
Query: 484 DQVLGKGCEGTFVYRGTFDK--RDVAVKRLLPECFTFADREVALLRESDA------HAHV 535
D+VLG G G VY G K RDVA+K + + F ++ + LR A H V
Sbjct: 586 DEVLGSGQFG-IVYGGKHRKTGRDVAIKII--DKLRFPTKQESQLRNEVAILQNLHHPGV 642
Query: 536 VRYYCTERDKQFRYIALELCSATLQDYV--EKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V C + ++ +E + + + +K I ++ Q + L HLH +
Sbjct: 643 VNLECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKF-LITQILVALRHLHFKN 701
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
IVH D+KP NVLL+ +V+ + DFG ++ IG SF RRS V GT ++APE++
Sbjct: 702 IVHCDLKPENVLLASADPFPQVK--LCDFGFAR--IIGEKSF-RRS-VVGTPAYLAPEVL 755
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGD 684
+ S+D++S+G + Y LS G PF +
Sbjct: 756 RNKGYNRSLDMWSVGVIIYVSLS-GTFPFNE 785
>U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein
kinase Krs-1 protein.
Length = 491
Score = 77.4 bits (182), Expect = 2e-13
Identities = 58/209 (27%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ V++ + VA+K++ E +E++++++ D+ +VV+
Sbjct: 27 FDVLEKLGEGSYGS-VFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDS-PYVVK 84
Query: 538 YYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVH 596
YY + +I +E C A ++ D + + + + IL+ GL +LH M +H
Sbjct: 85 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIH 144
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 145 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 196
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 197 GYNCVADIWSLG-ITSIEMAEGKPPYADI 224
>U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein.
Length = 491
Score = 77.4 bits (182), Expect = 2e-13
Identities = 58/209 (27%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ V++ + VA+K++ E +E++++++ D+ +VV+
Sbjct: 27 FDVLEKLGEGSYGS-VFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDS-PYVVK 84
Query: 538 YYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVH 596
YY + +I +E C A ++ D + + + + IL+ GL +LH M +H
Sbjct: 85 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIH 144
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 145 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 196
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 197 GYNCVADIWSLG-ITSIEMAEGKPPYADI 224
>L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13
protein.
Length = 676
Score = 77.4 bits (182), Expect = 2e-13
Identities = 74/229 (32%), Positives = 108/229 (47%), Gaps = 25/229 (10%)
Query: 468 EIGEGEMKIGKITFQTDQVLGKGCEGTFVY-----RGTFD-----KRDVAVKRLLPECFT 517
+I EG K F +VLGKG G + RG + K+DV + EC
Sbjct: 336 KIWEGSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTM 395
Query: 518 FADREVALLRESDAHAHVVRYYCTERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSV 576
R + L E+ H++ CT + K + +E L L +++ K FE +
Sbjct: 396 VEKRVLTLAAENPFLTHLI---CTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFEL-YRAT 451
Query: 577 EILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS 636
+ GL LHS I++RD+K NVLL G ++ I+DFG+ K+ G S
Sbjct: 452 FYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRD---GHIK--IADFGMCKENIFGE---S 503
Query: 637 RRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GD 684
R S GT +IAPE++ G + T S+D +S G + Y +L GQ PF GD
Sbjct: 504 RASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLI-GQSPFHGD 551
>D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-type
protein.
Length = 626
Score = 77.4 bits (182), Expect = 2e-13
Identities = 74/229 (32%), Positives = 108/229 (47%), Gaps = 25/229 (10%)
Query: 468 EIGEGEMKIGKITFQTDQVLGKGCEGTFVY-----RGTFD-----KRDVAVKRLLPECFT 517
+I EG K F +VLGKG G + RG + K+DV + EC
Sbjct: 286 KIWEGSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTM 345
Query: 518 FADREVALLRESDAHAHVVRYYCTERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSV 576
R + L E+ H++ CT + K + +E L L +++ K FE +
Sbjct: 346 VEKRVLTLAAENPFLTHLI---CTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFEL-YRAT 401
Query: 577 EILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS 636
+ GL LHS I++RD+K NVLL G ++ I+DFG+ K+ G S
Sbjct: 402 FYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRD---GHIK--IADFGMCKENIFGE---S 453
Query: 637 RRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GD 684
R S GT +IAPE++ G + T S+D +S G + Y +L GQ PF GD
Sbjct: 454 RASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLI-GQSPFHGD 501
>DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein.
Length = 914
Score = 77.4 bits (182), Expect = 2e-13
Identities = 68/211 (32%), Positives = 105/211 (49%), Gaps = 21/211 (9%)
Query: 484 DQVLGKGCEGTFVYRGTFDK--RDVAVKRLLPECFTFADREVALLRESDA------HAHV 535
D+VLG G G VY G K RDVA+K + + F ++ + LR A H V
Sbjct: 588 DEVLGSGQFG-IVYGGKHRKTGRDVAIKII--DKLRFPTKQESQLRNEVAILQNLHHPGV 644
Query: 536 VRYYCTERDKQFRYIALELCSATLQDYV--EKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V C + ++ +E + + + +K I ++ Q + L HLH +
Sbjct: 645 VNLECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKF-LITQILVALRHLHFKN 703
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
IVH D+KP NVLL+ +V+ + DFG ++ IG SF RRS V GT ++APE++
Sbjct: 704 IVHCDLKPENVLLASADPFPQVK--LCDFGFAR--IIGEKSF-RRS-VVGTPAYLAPEVL 757
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGD 684
+ S+D++S+G + Y LS G PF +
Sbjct: 758 RNKGYNRSLDMWSVGVIIYVSLS-GTFPFNE 787
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 77.4 bits (182), Expect = 2e-13
Identities = 66/247 (26%), Positives = 118/247 (47%), Gaps = 19/247 (7%)
Query: 481 FQTDQVLGKGCEGTFVY-RGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----HAH 534
F+ ++LG+G T V R R+ A+K L ++ + RE D H
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 141
Query: 535 VVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V+ Y T +D + Y L + L Y+ K +F+ + + + L +LH
Sbjct: 142 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD-ETCTRFYTAEIVSALEYLHGKG 200
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+KP N+LL+ ++ I+DFG +K L+ +R + GT +++PE++
Sbjct: 201 IIHRDLKPENILLN-----EDMHIQITDFGTAKVLS-PESKQARANSFVGTAQYVSPELL 254
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEEL 711
+ S D+++LGC+ Y +++ G PF G+ I+ +Y D +K P+
Sbjct: 255 TEKSACKSSDLWALGCIIYQLVA-GLPPFRAGNEYLIFQKIIKLEY--DFPEKFFPKARD 311
Query: 712 VVIKILI 718
+V K+L+
Sbjct: 312 LVEKLLV 318
>BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta
protein.
Length = 676
Score = 77.4 bits (182), Expect = 2e-13
Identities = 74/229 (32%), Positives = 108/229 (47%), Gaps = 25/229 (10%)
Query: 468 EIGEGEMKIGKITFQTDQVLGKGCEGTFVY-----RGTFD-----KRDVAVKRLLPECFT 517
+I EG K F +VLGKG G + RG + K+DV + EC
Sbjct: 336 KIWEGSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTM 395
Query: 518 FADREVALLRESDAHAHVVRYYCTERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSV 576
R + L E+ H++ CT + K + +E L L +++ K FE +
Sbjct: 396 VEKRVLTLAAENPFLTHLI---CTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFEL-YRAT 451
Query: 577 EILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS 636
+ GL LHS I++RD+K NVLL G ++ I+DFG+ K+ G S
Sbjct: 452 FYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRD---GHIK--IADFGMCKENIFGE---S 503
Query: 637 RRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GD 684
R S GT +IAPE++ G + T S+D +S G + Y +L GQ PF GD
Sbjct: 504 RASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLI-GQSPFHGD 551
>BC040457-1|AAH40457.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II alpha protein.
Length = 478
Score = 77.4 bits (182), Expect = 2e-13
Identities = 62/247 (25%), Positives = 115/247 (46%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 69 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 126
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 127 HQMGVVHRDLKPENLLLASKLKGAAVK--LADFGLAIEVEGEQQAW---FGFAGTPGYLS 181
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV----LRRQANILTGDYNLDHLDKI 705
PE++ + +D+++ G V Y+L G PF D L +Q D+ D +
Sbjct: 182 PEVLRKDPYGKPVDLWACG-VILYILLVGYPPFWDEDQHRLYKQIKAGAYDFPSPEWDTV 240
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ PS R LK+P + ++ + + + C F
Sbjct: 241 TPE-----AKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMH--RQETVDCLKKF 293
Query: 766 GAEHPLE 772
A L+
Sbjct: 294 NARRKLK 300
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 77.4 bits (182), Expect = 2e-13
Identities = 66/247 (26%), Positives = 118/247 (47%), Gaps = 19/247 (7%)
Query: 481 FQTDQVLGKGCEGTFVY-RGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----HAH 534
F+ ++LG+G T V R R+ A+K L ++ + RE D H
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 141
Query: 535 VVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V+ Y T +D + Y L + L Y+ K +F+ + + + L +LH
Sbjct: 142 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD-ETCTRFYTAEIVSALEYLHGKG 200
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+KP N+LL+ ++ I+DFG +K L+ +R + GT +++PE++
Sbjct: 201 IIHRDLKPENILLN-----EDMHIQITDFGTAKVLS-PESKQARANSFVGTAQYVSPELL 254
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEEL 711
+ S D+++LGC+ Y +++ G PF G+ I+ +Y D +K P+
Sbjct: 255 TEKSACKSSDLWALGCIIYQLVA-GLPPFRAGNEYLIFQKIIKLEY--DFPEKFFPKARD 311
Query: 712 VVIKILI 718
+V K+L+
Sbjct: 312 LVEKLLV 318
>BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase 3
(STE20 homolog, yeast) protein.
Length = 491
Score = 77.4 bits (182), Expect = 2e-13
Identities = 58/209 (27%), Positives = 111/209 (53%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ V++ + VA+K++ E +E++++++ D+ +VV+
Sbjct: 27 FDVLEKLGEGSYGS-VFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDS-PYVVK 84
Query: 538 YYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVH 596
YY + +I +E C A ++ D + + + + IL+ GL +LH M +H
Sbjct: 85 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIH 144
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT W+APE+I
Sbjct: 145 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIQEI 196
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 197 GYNCVADIWSLG-ITSIEMAEGKPPYADI 224
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 77.4 bits (182), Expect = 2e-13
Identities = 66/247 (26%), Positives = 118/247 (47%), Gaps = 19/247 (7%)
Query: 481 FQTDQVLGKGCEGTFVY-RGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----HAH 534
F+ ++LG+G T V R R+ A+K L ++ + RE D H
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 141
Query: 535 VVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V+ Y T +D + Y L + L Y+ K +F+ + + + L +LH
Sbjct: 142 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD-ETCTRFYTAEIVSALEYLHGKG 200
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+KP N+LL+ ++ I+DFG +K L+ +R + GT +++PE++
Sbjct: 201 IIHRDLKPENILLN-----EDMHIQITDFGTAKVLS-PESKQARANSFVGTAQYVSPELL 254
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEEL 711
+ S D+++LGC+ Y +++ G PF G+ I+ +Y D +K P+
Sbjct: 255 TEKSACKSSDLWALGCIIYQLVA-GLPPFRAGNEYLIFQKIIKLEY--DFPEKFFPKARD 311
Query: 712 VVIKILI 718
+V K+L+
Sbjct: 312 LVEKLLV 318
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 77.4 bits (182), Expect = 2e-13
Identities = 66/247 (26%), Positives = 118/247 (47%), Gaps = 19/247 (7%)
Query: 481 FQTDQVLGKGCEGTFVY-RGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----HAH 534
F+ ++LG+G T V R R+ A+K L ++ + RE D H
Sbjct: 74 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 133
Query: 535 VVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V+ Y T +D + Y L + L Y+ K +F+ + + + L +LH
Sbjct: 134 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD-ETCTRFYTAEIVSALEYLHGKG 192
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+KP N+LL+ ++ I+DFG +K L+ +R + GT +++PE++
Sbjct: 193 IIHRDLKPENILLN-----EDMHIQITDFGTAKVLS-PESKQARANSFVGTAQYVSPELL 246
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEEL 711
+ S D+++LGC+ Y +++ G PF G+ I+ +Y D +K P+
Sbjct: 247 TEKSACKSSDLWALGCIIYQLVA-GLPPFRAGNEYLIFQKIIKLEY--DFPEKFFPKARD 303
Query: 712 VVIKILI 718
+V K+L+
Sbjct: 304 LVEKLLV 310
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 77.4 bits (182), Expect = 2e-13
Identities = 66/247 (26%), Positives = 118/247 (47%), Gaps = 19/247 (7%)
Query: 481 FQTDQVLGKGCEGTFVY-RGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----HAH 534
F+ ++LG+G T V R R+ A+K L ++ + RE D H
Sbjct: 120 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 179
Query: 535 VVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V+ Y T +D + Y L + L Y+ K +F+ + + + L +LH
Sbjct: 180 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD-ETCTRFYTAEIVSALEYLHGKG 238
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+KP N+LL+ ++ I+DFG +K L+ +R + GT +++PE++
Sbjct: 239 IIHRDLKPENILLN-----EDMHIQITDFGTAKVLS-PESKQARANSFVGTAQYVSPELL 292
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEEL 711
+ S D+++LGC+ Y +++ G PF G+ I+ +Y D +K P+
Sbjct: 293 TEKSACKSSDLWALGCIIYQLVA-GLPPFRAGNEYLIFQKIIKLEY--DFPEKFFPKARD 349
Query: 712 VVIKILI 718
+V K+L+
Sbjct: 350 LVEKLLV 356
>AF145711-1|AAD30559.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha-B
subunit protein.
Length = 489
Score = 77.0 bits (181), Expect = 3e-13
Identities = 62/247 (25%), Positives = 115/247 (46%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 69 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 126
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 127 HQMGVVHRDLKPENLLLASKLKGAAVK--LADFGLAIEVEGEQQAW---FGFAGTPGYLS 181
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV----LRRQANILTGDYNLDHLDKI 705
PE++ + +D+++ G V Y+L G PF D L +Q D+ D +
Sbjct: 182 PEVLRKDPYGKPVDLWACG-VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ PS R LK+P + ++ + + + C F
Sbjct: 241 TPE-----AKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMH--RQETVDCLKKF 293
Query: 766 GAEHPLE 772
A L+
Sbjct: 294 NARRKLK 300
>AF145710-1|AAD30558.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha
subunit protein.
Length = 478
Score = 77.0 bits (181), Expect = 3e-13
Identities = 62/247 (25%), Positives = 115/247 (46%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 69 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 126
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 127 HQMGVVHRDLKPENLLLASKLKGAAVK--LADFGLAIEVEGEQQAW---FGFAGTPGYLS 181
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV----LRRQANILTGDYNLDHLDKI 705
PE++ + +D+++ G V Y+L G PF D L +Q D+ D +
Sbjct: 182 PEVLRKDPYGKPVDLWACG-VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ PS R LK+P + ++ + + + C F
Sbjct: 241 TPE-----AKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMH--RQETVDCLKKF 293
Query: 766 GAEHPLE 772
A L+
Sbjct: 294 NARRKLK 300
>AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent
protein kinase II alpha protein.
Length = 478
Score = 77.0 bits (181), Expect = 3e-13
Identities = 62/247 (25%), Positives = 115/247 (46%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 69 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 126
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 127 HQMGVVHRDLKPENLLLASKLKGAAVK--LADFGLAIEVEGEQQAW---FGFAGTPGYLS 181
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV----LRRQANILTGDYNLDHLDKI 705
PE++ + +D+++ G V Y+L G PF D L +Q D+ D +
Sbjct: 182 PEVLRKDPYGKPVDLWACG-VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ PS R LK+P + ++ + + + C F
Sbjct: 241 TPE-----AKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMH--RQETVDCLKKF 293
Query: 766 GAEHPLE 772
A L+
Sbjct: 294 NARRKLK 300
>AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein.
Length = 527
Score = 77.0 bits (181), Expect = 3e-13
Identities = 62/247 (25%), Positives = 115/247 (46%), Gaps = 21/247 (8%)
Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589
H ++VR + + ++ Y+ +L + +D V ++ E D+ ++Q + H
Sbjct: 118 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 175
Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649
H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++
Sbjct: 176 HQMGVVHRDLKPENLLLASKLKGAAVK--LADFGLAIEVEGEQQAW---FGFAGTPGYLS 230
Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV----LRRQANILTGDYNLDHLDKI 705
PE++ + +D+++ G V Y+L G PF D L +Q D+ D +
Sbjct: 231 PEVLRKDPYGKPVDLWACG-VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 289
Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765
PE K LI M++ PS R LK+P + ++ + + + C F
Sbjct: 290 TPE-----AKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMH--RQETVDCLKKF 342
Query: 766 GAEHPLE 772
A L+
Sbjct: 343 NARRKLK 349
>U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein.
Length = 626
Score = 76.6 bits (180), Expect = 4e-13
Identities = 51/158 (32%), Positives = 83/158 (52%), Gaps = 8/158 (5%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSV--EIL 579
E+ LL+ H +V+YY RD+ + + + + ++ + +SV +
Sbjct: 412 EIQLLKNLQ-HERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYT 470
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ G+S+LHS IVHRD+K N+L G V+ + DFG SK+L +S +
Sbjct: 471 RQILEGMSYLHSNMIVHRDIKGANILRD---SAGNVK--LGDFGASKRLQTICMSGTGMR 525
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSK 677
VTGT W++PE+I+GE D++SLGC +L++
Sbjct: 526 SVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTE 563
>DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated protein
kinase kinase kinase 3 variant 2 protein.
Length = 622
Score = 76.6 bits (180), Expect = 4e-13
Identities = 51/158 (32%), Positives = 83/158 (52%), Gaps = 8/158 (5%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSV--EIL 579
E+ LL+ H +V+YY RD+ + + + + ++ + +SV +
Sbjct: 408 EIQLLKNLQ-HERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYT 466
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ G+S+LHS IVHRD+K N+L G V+ + DFG SK+L +S +
Sbjct: 467 RQILEGMSYLHSNMIVHRDIKGANILRD---SAGNVK--LGDFGASKRLQTICMSGTGMR 521
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSK 677
VTGT W++PE+I+GE D++SLGC +L++
Sbjct: 522 SVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTE 559
>CR542210-1|CAG47006.1| 372|Homo sapiens STK17B protein.
Length = 372
Score = 76.6 bits (180), Expect = 4e-13
Identities = 48/172 (27%), Positives = 90/172 (52%), Gaps = 10/172 (5%)
Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633
D + +++Q G+ +LH +IVH D+KP N+LLS G+++ I DFG+S+K IG
Sbjct: 134 DVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIK--IVDFGMSRK--IGHA 189
Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANIL 693
R + GT ++APE++N + TT+ D++++G + Y +L+ PF ++ +
Sbjct: 190 CELRE--IMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTH-TSPFVGEDNQETYLN 246
Query: 694 TGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQ 745
N+D+ ++ + I++++ P P E L + W +Q
Sbjct: 247 ISQVNVDYSEETFSSVSQLATD-FIQSLLVKNPEKGPTAEICLSHS--WLQQ 295
>BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protein
kinase 2 protein.
Length = 370
Score = 76.6 bits (180), Expect = 4e-13
Identities = 63/223 (28%), Positives = 113/223 (50%), Gaps = 14/223 (6%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV++LR+ H +V+ + ++ + LEL S L D++ +K + + ++
Sbjct: 72 EREVSILRQV-LHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLS-EEEATSF 129
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
++Q G+++LH+ I H D+KP N++L + + DFGL+ ++ G V F
Sbjct: 130 IKQILDGVNYLHTKKIAHFDLKPENIML-LDKNIPIPHIKLIDFGLAHEIEDG-VEFKN- 186
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQ-ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF GD + ANI
Sbjct: 187 --IFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANITAVS 243
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y+ D + EL K IR ++ + R + L++P
Sbjct: 244 YDFDE-EFFSQTSELA--KDFIRKLLVKETRKRLTIQEALRHP 283
>BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3, isoform 2 protein.
Length = 626
Score = 76.6 bits (180), Expect = 4e-13
Identities = 51/158 (32%), Positives = 83/158 (52%), Gaps = 8/158 (5%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSV--EIL 579
E+ LL+ H +V+YY RD+ + + + + ++ + +SV +
Sbjct: 412 EIQLLKNLQ-HERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYT 470
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ G+S+LHS IVHRD+K N+L G V+ + DFG SK+L +S +
Sbjct: 471 RQILEGMSYLHSNMIVHRDIKGANILRD---SAGNVK--LGDFGASKRLQTICMSGTGMR 525
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSK 677
VTGT W++PE+I+GE D++SLGC +L++
Sbjct: 526 SVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTE 563
>BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3, isoform 2 protein.
Length = 626
Score = 76.6 bits (180), Expect = 4e-13
Identities = 51/158 (32%), Positives = 83/158 (52%), Gaps = 8/158 (5%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSV--EIL 579
E+ LL+ H +V+YY RD+ + + + + ++ + +SV +
Sbjct: 412 EIQLLKNLQ-HERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYT 470
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ G+S+LHS IVHRD+K N+L G V+ + DFG SK+L +S +
Sbjct: 471 RQILEGMSYLHSNMIVHRDIKGANILRD---SAGNVK--LGDFGASKRLQTICMSGTGMR 525
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSK 677
VTGT W++PE+I+GE D++SLGC +L++
Sbjct: 526 SVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTE 563
>BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3 protein.
Length = 626
Score = 76.6 bits (180), Expect = 4e-13
Identities = 51/158 (32%), Positives = 83/158 (52%), Gaps = 8/158 (5%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSV--EIL 579
E+ LL+ H +V+YY RD+ + + + + ++ + +SV +
Sbjct: 412 EIQLLKNLQ-HERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYT 470
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ G+S+LHS IVHRD+K N+L G V+ + DFG SK+L +S +
Sbjct: 471 RQILEGMSYLHSNMIVHRDIKGANILRD---SAGNVK--LGDFGASKRLQTICMSGTGMR 525
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSK 677
VTGT W++PE+I+GE D++SLGC +L++
Sbjct: 526 SVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTE 563
>BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for
IMAGE:3506235) protein.
Length = 594
Score = 76.6 bits (180), Expect = 4e-13
Identities = 51/158 (32%), Positives = 83/158 (52%), Gaps = 8/158 (5%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSV--EIL 579
E+ LL+ H +V+YY RD+ + + + + ++ + +SV +
Sbjct: 380 EIQLLKNLQ-HERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYT 438
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ G+S+LHS IVHRD+K N+L G V+ + DFG SK+L +S +
Sbjct: 439 RQILEGMSYLHSNMIVHRDIKGANILRD---SAGNVK--LGDFGASKRLQTICMSGTGMR 493
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSK 677
VTGT W++PE+I+GE D++SLGC +L++
Sbjct: 494 SVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTE 531
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 76.6 bits (180), Expect = 4e-13
Identities = 66/247 (26%), Positives = 118/247 (47%), Gaps = 19/247 (7%)
Query: 481 FQTDQVLGKGCEGTFVY-RGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----HAH 534
F+ ++LG+G T V R R+ A+K L ++ + RE D H
Sbjct: 55 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 114
Query: 535 VVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V+ Y T +D + Y L + L Y+ K +F+ + + + L +LH
Sbjct: 115 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD-ETCTRFYTAEIVSALEYLHGKG 173
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I+HRD+KP N+LL+ ++ I+DFG +K L+ +R + GT +++PE++
Sbjct: 174 IIHRDLKPENILLN-----EDMYIQITDFGTAKVLS-PESKQARANSFVGTAQYVSPELL 227
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEEL 711
+ S D+++LGC+ Y +++ G PF G+ I+ +Y D +K P+
Sbjct: 228 TEKSACKSSDLWALGCIIYQLVA-GLPPFRAGNEYLIFQKIIKLEY--DFPEKFFPKARD 284
Query: 712 VVIKILI 718
+V K+L+
Sbjct: 285 LVEKLLV 291
>AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related protein
1 protein.
Length = 370
Score = 76.6 bits (180), Expect = 4e-13
Identities = 63/223 (28%), Positives = 114/223 (51%), Gaps = 14/223 (6%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV++LR+ H +V+ + ++ + LEL S L D++ +K + + ++
Sbjct: 72 EREVSILRQV-LHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLS-EEEATSF 129
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
++Q G+++LH+ I H D+KP N++L + + DFGL+ ++ G V F
Sbjct: 130 IKQILDGVNYLHTKKIAHFDLKPENIML-LDKNIPIPHIKLIDFGLAHEIEDG-VEFKN- 186
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQ-ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF GD + ANI +
Sbjct: 187 --IFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANITSVS 243
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y+ D + EL K IR ++ + R + L++P
Sbjct: 244 YDFDE-EFFSHTSELA--KDFIRKLLVKETRKRLTIQEALRHP 283
>AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protein
kinase 2 protein.
Length = 370
Score = 76.6 bits (180), Expect = 4e-13
Identities = 63/223 (28%), Positives = 113/223 (50%), Gaps = 14/223 (6%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+REV++LR+ H +V+ + ++ + LEL S L D++ +K + + ++
Sbjct: 72 EREVSILRQV-LHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLS-EEEATSF 129
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
++Q G+++LH+ I H D+KP N++L + + DFGL+ ++ G V F
Sbjct: 130 IKQILDGVNYLHTKKIAHFDLKPENIML-LDKNIPIPHIKLIDFGLAHEIEDG-VEFKN- 186
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQ-ANILTGD 696
+ GT ++APE++N E D++S+G + Y +LS G PF GD + ANI
Sbjct: 187 --IFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANITAVS 243
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y+ D + EL K IR ++ + R + L++P
Sbjct: 244 YDFDE-EFFSQTSELA--KDFIRKLLVKETRKRLTIQEALRHP 283
>BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 76.2 bits (179), Expect = 5e-13
Identities = 60/209 (28%), Positives = 110/209 (52%), Gaps = 15/209 (7%)
Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPEC-FTFADREVALLRESDAHAHVVR 537
F + LG+G G+ VY+ + VA+K++ E +E++++++ D+ HVV+
Sbjct: 30 FDVLEKLGEGSYGS-VYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDS-PHVVK 87
Query: 538 YYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATM-GLSHLHSMDIVH 596
YY + +I +E C A + + N D + + Q+T+ GL +LH M +H
Sbjct: 88 YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIH 147
Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656
RD+K N+LL+ E A ++DFG++ +L + ++R+ V GT +APE+I
Sbjct: 148 RDIKAGNILLNT-----EGHAKLADFGVAGQLT---DTMAKRNTVIGTPFLMAPEVIQEI 199
Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685
DI+SLG + +++G+ P+ D+
Sbjct: 200 GYNCVADIWSLG-ITAIEMAEGKPPYADI 227
>BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein.
Length = 1036
Score = 75.8 bits (178), Expect = 7e-13
Identities = 59/220 (26%), Positives = 108/220 (49%), Gaps = 22/220 (10%)
Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKR---DVAVKRL----LPECFTFADREVALLRE 528
+G + ++G G V+RG ++ +VA+K + L + +E+ +L+E
Sbjct: 4 VGDFEYSKRDLVGHGAFAV-VFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKE 62
Query: 529 SDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI-LRQATMGL 586
H ++V Y + ++ +E C+ L DY++ K D++ + L Q +
Sbjct: 63 LQ-HENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLS--EDTIRVFLHQIAAAM 119
Query: 587 SHLHSMDIVHRDVKPHNVLLS----MPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVT 642
LHS I+HRD+KP N+LLS S +R I+DFG ++ L+ ++ + +
Sbjct: 120 RILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMA----ATLC 175
Query: 643 GTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
G+ ++APE+I + D++S+G V Y L G+ PF
Sbjct: 176 GSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCL-VGKPPF 214
>AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein.
Length = 1100
Score = 75.8 bits (178), Expect = 7e-13
Identities = 59/220 (26%), Positives = 108/220 (49%), Gaps = 22/220 (10%)
Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKR---DVAVKRL----LPECFTFADREVALLRE 528
+G + ++G G V+RG ++ +VA+K + L + +E+ +L+E
Sbjct: 68 VGDFEYSKRDLVGHGAFAV-VFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKE 126
Query: 529 SDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI-LRQATMGL 586
H ++V Y + ++ +E C+ L DY++ K D++ + L Q +
Sbjct: 127 LQ-HENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLS--EDTIRVFLHQIAAAM 183
Query: 587 SHLHSMDIVHRDVKPHNVLLS----MPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVT 642
LHS I+HRD+KP N+LLS S +R I+DFG ++ L+ ++ + +
Sbjct: 184 RILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMA----ATLC 239
Query: 643 GTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
G+ ++APE+I + D++S+G V Y L G+ PF
Sbjct: 240 GSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCL-VGKPPF 278
>CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein.
Length = 431
Score = 75.4 bits (177), Expect = 9e-13
Identities = 76/278 (27%), Positives = 137/278 (49%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ +V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-PYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D +E E +I + ILR+ GL +LHS +HRD+
Sbjct: 88 SYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIAT--ILREILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S GEV+ ++D G++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEHGEVK--LADIGVAGQLTDTQI---KRNTFVGTPFWMAPEVIKQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L++G+ P ++ + L N L+ + +K +
Sbjct: 198 SKADIWSLG-ITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKP----LKEFVE 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ +PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR 290
>BC064422-1|AAH64422.1| 241|Homo sapiens PNCK protein protein.
Length = 241
Score = 75.4 bits (177), Expect = 9e-13
Identities = 52/167 (31%), Positives = 86/167 (51%), Gaps = 13/167 (7%)
Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633
D+ ++ Q +S+LHS+ IVHRD+KP N+L + P ++ M+SDFGLS K+ G +
Sbjct: 10 DASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKI--MVSDFGLS-KIQAGNM 66
Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--AN 691
GT G++APE++ + ++D+++LG V Y+L G PF D + +
Sbjct: 67 ----LGTACGTPGYVAPELLEQKPYGKAVDVWALG-VISYILLCGYPPFYDESDPELFSQ 121
Query: 692 ILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKY 738
IL Y D ++ K IR ++ P R C+ L++
Sbjct: 122 ILRASY---EFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALRH 165
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 75.4 bits (177), Expect = 9e-13
Identities = 68/250 (27%), Positives = 121/250 (48%), Gaps = 25/250 (10%)
Query: 481 FQTDQVLGKGCEGTFVY-RGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----HAH 534
F+ ++LG+G T V R R+ A+K L ++ + RE D H
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 141
Query: 535 VVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFE--C-KIDSVEILRQATMGLSHLH 590
V+ Y T +D + Y L + L Y+ K +F+ C + + EI+ + +LH
Sbjct: 142 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSAS----EYLH 197
Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650
I+HRD+KP N+LL+ ++ I+DFG +K L+ +R + GT +++P
Sbjct: 198 GKGIIHRDLKPENILLNE-----DMHIQITDFGTAKVLS-PESKQARANSFVGTAQYVSP 251
Query: 651 EMINGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPE 708
E++ + S D+++LGC+ Y +++ G PF G+ I+ +Y D +K P+
Sbjct: 252 ELLTEKSACKSSDLWALGCIIYQLVA-GLPPFRAGNEYLIFQKIIKLEY--DFPEKFFPK 308
Query: 709 EELVVIKILI 718
+V K+L+
Sbjct: 309 ARDLVEKLLV 318
>AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein.
Length = 890
Score = 75.4 bits (177), Expect = 9e-13
Identities = 67/210 (31%), Positives = 105/210 (50%), Gaps = 19/210 (9%)
Query: 484 DQVLGKGCEGTFVYRGTFDK--RDVAVKRLLPECFTFADR-----EVALLRESDAHAHVV 536
D+VLG G G VY G K RDVA+K + F EVA+L+ H +V
Sbjct: 579 DEVLGSGQFG-IVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLH-HPGIV 636
Query: 537 RYYCTERDKQFRYIALELCSATLQDYV--EKKLNFECKIDSVEILRQATMGLSHLHSMDI 594
C + ++ +E + + + +K +I ++ Q + L +LH +I
Sbjct: 637 NLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKF-MVTQILVALRNLHFKNI 695
Query: 595 VHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN 654
VH D+KP NVLL+ +V+ + DFG ++ IG SF RRS V GT ++APE++
Sbjct: 696 VHCDLKPENVLLASAEPFPQVK--LCDFGFARI--IGEKSF-RRS-VVGTPAYLAPEVLR 749
Query: 655 GERTTTSIDIFSLGCVFYYVLSKGQHPFGD 684
+ S+D++S+G + Y LS G PF +
Sbjct: 750 SKGYNRSLDMWSVGVIIYVSLS-GTFPFNE 778
>AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase
protein.
Length = 890
Score = 75.4 bits (177), Expect = 9e-13
Identities = 67/210 (31%), Positives = 105/210 (50%), Gaps = 19/210 (9%)
Query: 484 DQVLGKGCEGTFVYRGTFDK--RDVAVKRLLPECFTFADR-----EVALLRESDAHAHVV 536
D+VLG G G VY G K RDVA+K + F EVA+L+ H +V
Sbjct: 579 DEVLGSGQFG-IVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLH-HPGIV 636
Query: 537 RYYCTERDKQFRYIALELCSATLQDYV--EKKLNFECKIDSVEILRQATMGLSHLHSMDI 594
C + ++ +E + + + +K +I ++ Q + L +LH +I
Sbjct: 637 NLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKF-MVTQILVALRNLHFKNI 695
Query: 595 VHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN 654
VH D+KP NVLL+ +V+ + DFG ++ IG SF RRS V GT ++APE++
Sbjct: 696 VHCDLKPENVLLASAEPFPQVK--LCDFGFARI--IGEKSF-RRS-VVGTPAYLAPEVLR 749
Query: 655 GERTTTSIDIFSLGCVFYYVLSKGQHPFGD 684
+ S+D++S+G + Y LS G PF +
Sbjct: 750 SKGYNRSLDMWSVGVIIYVSLS-GTFPFNE 778
>BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein.
Length = 625
Score = 74.5 bits (175), Expect = 2e-12
Identities = 72/223 (32%), Positives = 109/223 (48%), Gaps = 26/223 (11%)
Query: 480 TFQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLP--ECFTFADREVALLRESDAHAHVV 536
T++ + +GKG G F + + AVK L P + + E +L+ H +VV
Sbjct: 20 TWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVV 79
Query: 537 RYYCT--ERDK---QFRYIALELCSA-TLQDYVEKKLNFECKIDS---VEILRQATMGLS 587
R+Y ++DK ++ LELCS ++ D V+ L ++ IL +A MGL
Sbjct: 80 RFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQ 139
Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647
HLH+ +HRDVK +N+LL+ G + DFG+S +L R RR+ GT W
Sbjct: 140 HLHNNKTIHRDVKGNNILLTTEGG-----VKLVDFGVSAQLTSTR---HRRNTSVGTPFW 191
Query: 648 IAPEMINGER---TT--TSIDIFSLGCVFYYVLSKGQHPFGDV 685
+APE+I E+ TT D +SLG + L G P D+
Sbjct: 192 MAPEVIACEQQLDTTYDARCDTWSLG-ITAIELGDGDPPLADL 233
>BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein.
Length = 664
Score = 74.5 bits (175), Expect = 2e-12
Identities = 72/223 (32%), Positives = 109/223 (48%), Gaps = 26/223 (11%)
Query: 480 TFQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLP--ECFTFADREVALLRESDAHAHVV 536
T++ + +GKG G F + + AVK L P + + E +L+ H +VV
Sbjct: 20 TWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVV 79
Query: 537 RYYCT--ERDK---QFRYIALELCSA-TLQDYVEKKLNFECKIDS---VEILRQATMGLS 587
R+Y ++DK ++ LELCS ++ D V+ L ++ IL +A MGL
Sbjct: 80 RFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQ 139
Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647
HLH+ +HRDVK +N+LL+ G + DFG+S +L R RR+ GT W
Sbjct: 140 HLHNNKTIHRDVKGNNILLTTEGG-----VKLVDFGVSAQLTSTR---HRRNTSVGTPFW 191
Query: 648 IAPEMINGER---TT--TSIDIFSLGCVFYYVLSKGQHPFGDV 685
+APE+I E+ TT D +SLG + L G P D+
Sbjct: 192 MAPEVIACEQQLDTTYDARCDTWSLG-ITAIELGDGDPPLADL 233
>BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein.
Length = 247
Score = 74.5 bits (175), Expect = 2e-12
Identities = 72/223 (32%), Positives = 109/223 (48%), Gaps = 26/223 (11%)
Query: 480 TFQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLP--ECFTFADREVALLRESDAHAHVV 536
T++ + +GKG G F + + AVK L P + + E +L+ H +VV
Sbjct: 20 TWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVV 79
Query: 537 RYYCT--ERDK---QFRYIALELCSA-TLQDYVEKKLNFECKIDS---VEILRQATMGLS 587
R+Y ++DK ++ LELCS ++ D V+ L ++ IL +A MGL
Sbjct: 80 RFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQ 139
Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647
HLH+ +HRDVK +N+LL+ G + DFG+S +L R RR+ GT W
Sbjct: 140 HLHNNKTIHRDVKGNNILLTTEGG-----VKLVDFGVSAQLTSTR---HRRNTSVGTPFW 191
Query: 648 IAPEMINGER---TT--TSIDIFSLGCVFYYVLSKGQHPFGDV 685
+APE+I E+ TT D +SLG + L G P D+
Sbjct: 192 MAPEVIACEQQLDTTYDARCDTWSLG-ITAIELGDGDPPLADL 233
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 74.5 bits (175), Expect = 2e-12
Identities = 78/268 (29%), Positives = 127/268 (47%), Gaps = 29/268 (10%)
Query: 481 FQTDQVLGKGCEGTF---VYRGTFDKRDVAV---KRLLPECFTFADREVALLRESDAHAH 534
++ ++ LGKG G V+ T K + + ++L +RE+A+L+ + H H
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE-HPH 77
Query: 535 VVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V++ + +K++ Y+ LE S L DY+ KK K ++ + RQ L HS
Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK-EARKFFRQIISALDFCHSHS 136
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I HRD+KP N+LL + +R I+DFG++ L +G S G+ + PE+I
Sbjct: 137 ICHRDLKPENLLLDEKN---NIR--IADFGMA-SLQVGD---SLLETSCGSPHYACPEVI 187
Query: 654 NGER-TTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDHLDKILPEEE 710
GE+ D++S G V + L G PF D RQ + G +++ H I P+
Sbjct: 188 RGEKYDGRKADVWSCG-VILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHF--IPPD-- 242
Query: 711 LVVIKILIRAMISAKPSARPPCETILKY 738
+ L+R MI + R E I K+
Sbjct: 243 ---CQSLLRGMIEVDAARRLTLEHIQKH 267
>AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 74.5 bits (175), Expect = 2e-12
Identities = 72/223 (32%), Positives = 109/223 (48%), Gaps = 26/223 (11%)
Query: 480 TFQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLP--ECFTFADREVALLRESDAHAHVV 536
T++ + +GKG G F + + AVK L P + + E +L+ H +VV
Sbjct: 20 TWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVV 79
Query: 537 RYYCT--ERDK---QFRYIALELCSA-TLQDYVEKKLNFECKIDS---VEILRQATMGLS 587
R+Y ++DK ++ LELCS ++ D V+ L ++ IL +A MGL
Sbjct: 80 RFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQ 139
Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647
HLH+ +HRDVK +N+LL+ G + DFG+S +L R RR+ GT W
Sbjct: 140 HLHNNKTIHRDVKGNNILLTTEGG-----VKLVDFGVSAQLTSTR---HRRNTSVGTPFW 191
Query: 648 IAPEMINGER---TT--TSIDIFSLGCVFYYVLSKGQHPFGDV 685
+APE+I E+ TT D +SLG + L G P D+
Sbjct: 192 MAPEVIACEQQLDTTYDARCDTWSLG-ITAIELGDGDPPLADL 233
>AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 74.5 bits (175), Expect = 2e-12
Identities = 72/223 (32%), Positives = 109/223 (48%), Gaps = 26/223 (11%)
Query: 480 TFQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLP--ECFTFADREVALLRESDAHAHVV 536
T++ + +GKG G F + + AVK L P + + E +L+ H +VV
Sbjct: 20 TWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVV 79
Query: 537 RYYCT--ERDK---QFRYIALELCSA-TLQDYVEKKLNFECKIDS---VEILRQATMGLS 587
R+Y ++DK ++ LELCS ++ D V+ L ++ IL +A MGL
Sbjct: 80 RFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQ 139
Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647
HLH+ +HRDVK +N+LL+ G + DFG+S +L R RR+ GT W
Sbjct: 140 HLHNNKTIHRDVKGNNILLTTEGG-----VKLVDFGVSAQLTSTR---HRRNTSVGTPFW 191
Query: 648 IAPEMINGER---TT--TSIDIFSLGCVFYYVLSKGQHPFGDV 685
+APE+I E+ TT D +SLG + L G P D+
Sbjct: 192 MAPEVIACEQQLDTTYDARCDTWSLG-ITAIELGDGDPPLADL 233
>AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 74.5 bits (175), Expect = 2e-12
Identities = 72/223 (32%), Positives = 109/223 (48%), Gaps = 26/223 (11%)
Query: 480 TFQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLP--ECFTFADREVALLRESDAHAHVV 536
T++ + +GKG G F + + AVK L P + + E +L+ H +VV
Sbjct: 20 TWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVV 79
Query: 537 RYYCT--ERDK---QFRYIALELCSA-TLQDYVEKKLNFECKIDS---VEILRQATMGLS 587
R+Y ++DK ++ LELCS ++ D V+ L ++ IL +A MGL
Sbjct: 80 RFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQ 139
Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647
HLH+ +HRDVK +N+LL+ G + DFG+S +L R RR+ GT W
Sbjct: 140 HLHNNKTIHRDVKGNNILLTTEGG-----VKLVDFGVSAQLTSTR---HRRNTSVGTPFW 191
Query: 648 IAPEMINGER---TT--TSIDIFSLGCVFYYVLSKGQHPFGDV 685
+APE+I E+ TT D +SLG + L G P D+
Sbjct: 192 MAPEVIACEQQLDTTYDARCDTWSLG-ITAIELGDGDPPLADL 233
>AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein.
Length = 247
Score = 74.5 bits (175), Expect = 2e-12
Identities = 72/223 (32%), Positives = 109/223 (48%), Gaps = 26/223 (11%)
Query: 480 TFQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLP--ECFTFADREVALLRESDAHAHVV 536
T++ + +GKG G F + + AVK L P + + E +L+ H +VV
Sbjct: 20 TWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVV 79
Query: 537 RYYCT--ERDK---QFRYIALELCSA-TLQDYVEKKLNFECKIDS---VEILRQATMGLS 587
R+Y ++DK ++ LELCS ++ D V+ L ++ IL +A MGL
Sbjct: 80 RFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQ 139
Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647
HLH+ +HRDVK +N+LL+ G + DFG+S +L R RR+ GT W
Sbjct: 140 HLHNNKTIHRDVKGNNILLTTEGG-----VKLVDFGVSAQLTSTR---HRRNTSVGTPFW 191
Query: 648 IAPEMINGER---TT--TSIDIFSLGCVFYYVLSKGQHPFGDV 685
+APE+I E+ TT D +SLG + L G P D+
Sbjct: 192 MAPEVIACEQQLDTTYDARCDTWSLG-ITAIELGDGDPPLADL 233
>AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 74.5 bits (175), Expect = 2e-12
Identities = 72/223 (32%), Positives = 109/223 (48%), Gaps = 26/223 (11%)
Query: 480 TFQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLP--ECFTFADREVALLRESDAHAHVV 536
T++ + +GKG G F + + AVK L P + + E +L+ H +VV
Sbjct: 20 TWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVV 79
Query: 537 RYYCT--ERDK---QFRYIALELCSA-TLQDYVEKKLNFECKIDS---VEILRQATMGLS 587
R+Y ++DK ++ LELCS ++ D V+ L ++ IL +A MGL
Sbjct: 80 RFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQ 139
Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647
HLH+ +HRDVK +N+LL+ G + DFG+S +L R RR+ GT W
Sbjct: 140 HLHNNKTIHRDVKGNNILLTTEGG-----VKLVDFGVSAQLTSTR---HRRNTSVGTPFW 191
Query: 648 IAPEMINGER---TT--TSIDIFSLGCVFYYVLSKGQHPFGDV 685
+APE+I E+ TT D +SLG + L G P D+
Sbjct: 192 MAPEVIACEQQLDTTYDARCDTWSLG-ITAIELGDGDPPLADL 233
>AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 74.5 bits (175), Expect = 2e-12
Identities = 72/223 (32%), Positives = 109/223 (48%), Gaps = 26/223 (11%)
Query: 480 TFQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLP--ECFTFADREVALLRESDAHAHVV 536
T++ + +GKG G F + + AVK L P + + E +L+ H +VV
Sbjct: 20 TWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVV 79
Query: 537 RYYCT--ERDK---QFRYIALELCSA-TLQDYVEKKLNFECKIDS---VEILRQATMGLS 587
R+Y ++DK ++ LELCS ++ D V+ L ++ IL +A MGL
Sbjct: 80 RFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQ 139
Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647
HLH+ +HRDVK +N+LL+ G + DFG+S +L R RR+ GT W
Sbjct: 140 HLHNNKTIHRDVKGNNILLTTEGG-----VKLVDFGVSAQLTSTR---HRRNTSVGTPFW 191
Query: 648 IAPEMINGER---TT--TSIDIFSLGCVFYYVLSKGQHPFGDV 685
+APE+I E+ TT D +SLG + L G P D+
Sbjct: 192 MAPEVIACEQQLDTTYDARCDTWSLG-ITAIELGDGDPPLADL 233
>AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein.
Length = 1615
Score = 74.5 bits (175), Expect = 2e-12
Identities = 72/223 (32%), Positives = 109/223 (48%), Gaps = 26/223 (11%)
Query: 480 TFQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLP--ECFTFADREVALLRESDAHAHVV 536
T++ + +GKG G F + + AVK L P + + E +L+ H +VV
Sbjct: 20 TWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVV 79
Query: 537 RYYCT--ERDK---QFRYIALELCSA-TLQDYVEKKLNFECKIDS---VEILRQATMGLS 587
R+Y ++DK ++ LELCS ++ D V+ L ++ IL +A MGL
Sbjct: 80 RFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQ 139
Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647
HLH+ +HRDVK +N+LL+ G + DFG+S +L R RR+ GT W
Sbjct: 140 HLHNNKTIHRDVKGNNILLTTEGG-----VKLVDFGVSAQLTSTR---HRRNTSVGTPFW 191
Query: 648 IAPEMINGER---TT--TSIDIFSLGCVFYYVLSKGQHPFGDV 685
+APE+I E+ TT D +SLG + L G P D+
Sbjct: 192 MAPEVIACEQQLDTTYDARCDTWSLG-ITAIELGDGDPPLADL 233
>AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing
kinase protein.
Length = 966
Score = 74.5 bits (175), Expect = 2e-12
Identities = 69/247 (27%), Positives = 119/247 (48%), Gaps = 21/247 (8%)
Query: 485 QVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERD 544
Q LG G +G V+ G F +VA+K++ + T ++ LR+ H +++ +
Sbjct: 172 QWLGSGAQGA-VFLGKFRAEEVAIKKVREQNET----DIKHLRKLK-HPNIIAFKGVCTQ 225
Query: 545 KQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHN 603
I +E C+ L + + ++ V+ G+++LH I+HRD+K N
Sbjct: 226 APCYCIIMEYCAHGQLYEVLRAGRKITPRL-LVDWSTGIASGMNYLHLHKIIHRDLKSPN 284
Query: 604 VLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSID 663
VL++ T V+ ISDFG SK+L+ S + GT W+APE+I E + +D
Sbjct: 285 VLVTH---TDAVK--ISDFGTSKELS----DKSTKMSFAGTVAWMAPEVIRNEPVSEKVD 335
Query: 664 IFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMIS 723
I+S G V + +L+ G+ P+ DV ++ + + L +P KIL++
Sbjct: 336 IWSFGVVLWELLT-GEIPYKDV---DSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQ 391
Query: 724 AKPSARP 730
+KP RP
Sbjct: 392 SKPRNRP 398
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 74.1 bits (174), Expect = 2e-12
Identities = 59/210 (28%), Positives = 109/210 (51%), Gaps = 18/210 (8%)
Query: 485 QVLGKGCEGTFVYRGTFDKRDV--AVKRLLPE-----CFTFADREVALLRESDAHAHVVR 537
++LGKG G V T + + A+K++ E +REV +L+ S H H++
Sbjct: 120 RILGKGSFG-IVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILK-SVKHEHIIH 177
Query: 538 YYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVH 596
+ Y+ +ELC L++ +++K +F + ++ I++ +++LH+ DIVH
Sbjct: 178 LEQVFETPKKMYLVMELCEDGELKEILDRKGHFS-ENETRWIIQSLASAIAYLHNNDIVH 236
Query: 597 RDVKPHNVLL--SMPSGTGEV--RAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652
RD+K N+++ S+ E+ ++DFGL+ K S + GT ++APE+
Sbjct: 237 RDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQ--SRSEAMLQATCGTPIYMAPEV 294
Query: 653 INGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
I+ + DI+S+G V Y +L +G+ PF
Sbjct: 295 ISAHDYSQQCDIWSIGVVMYMLL-RGEPPF 323
>AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 4 isoform b variant protein.
Length = 765
Score = 74.1 bits (174), Expect = 2e-12
Identities = 57/181 (31%), Positives = 92/181 (50%), Gaps = 8/181 (4%)
Query: 504 RDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDY 562
++ AVK L REVA LR +H +VV + D+ Y+ LEL L ++
Sbjct: 428 QEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQPHTYLVLELLRGGELLEH 487
Query: 563 VEKKLNFECKIDSVEILRQATMGLSHLH-SMDIVHRDVKPHNVLLSMPSGTGEVRAMISD 621
+ KK +F + ++ +ILR +S +H +VHRD+KP N+L + + V+ I D
Sbjct: 488 IRKKRHFS-ESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVK--IID 544
Query: 622 FGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHP 681
FG + +L ++ T + APE++ + S D++SLG + Y +LS GQ P
Sbjct: 545 FGFA-RLRPQSPGVPMQTPCF-TLQYAAPELLAQQGYDESCDLWSLGVILYMMLS-GQVP 601
Query: 682 F 682
F
Sbjct: 602 F 602
Score = 50.4 bits (115), Expect = 3e-05
Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 9/103 (8%)
Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640
+ + L HLH + I++RD+K NVLL E +++DFGLSK+ R
Sbjct: 144 EIVLALEHLHKLGIIYRDLKLENVLLD-----SEGHIVLTDFGLSKEFLTEEK--ERTFS 196
Query: 641 VTGTDGWIAPEMINGER-TTTSIDIFSLGCVFYYVLSKGQHPF 682
GT ++APE+I + ++D +SLG + + +L+ G PF
Sbjct: 197 FCGTIEYMAPEIIRSKTGHGKAVDWWSLGILLFELLT-GASPF 238
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 74.1 bits (174), Expect = 2e-12
Identities = 59/210 (28%), Positives = 109/210 (51%), Gaps = 18/210 (8%)
Query: 485 QVLGKGCEGTFVYRGTFDKRDV--AVKRLLPE-----CFTFADREVALLRESDAHAHVVR 537
++LGKG G V T + + A+K++ E +REV +L+ S H H++
Sbjct: 120 RILGKGSFG-IVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILK-SVKHEHIIH 177
Query: 538 YYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVH 596
+ Y+ +ELC L++ +++K +F + ++ I++ +++LH+ DIVH
Sbjct: 178 LEQVFETPKKMYLVMELCEDGELKEILDRKGHFS-ENETRWIIQSLASAIAYLHNNDIVH 236
Query: 597 RDVKPHNVLL--SMPSGTGEV--RAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652
RD+K N+++ S+ E+ ++DFGL+ K S + GT ++APE+
Sbjct: 237 RDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQ--SRSEAMLQATCGTPIYMAPEV 294
Query: 653 INGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
I+ + DI+S+G V Y +L +G+ PF
Sbjct: 295 ISAHDYSQQCDIWSIGVVMYMLL-RGEPPF 323
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 74.1 bits (174), Expect = 2e-12
Identities = 59/210 (28%), Positives = 109/210 (51%), Gaps = 18/210 (8%)
Query: 485 QVLGKGCEGTFVYRGTFDKRDV--AVKRLLPE-----CFTFADREVALLRESDAHAHVVR 537
++LGKG G V T + + A+K++ E +REV +L+ S H H++
Sbjct: 120 RILGKGSFG-IVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILK-SVKHEHIIH 177
Query: 538 YYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVH 596
+ Y+ +ELC L++ +++K +F + ++ I++ +++LH+ DIVH
Sbjct: 178 LEQVFETPKKMYLVMELCEDGELKEILDRKGHFS-ENETRWIIQSLASAIAYLHNNDIVH 236
Query: 597 RDVKPHNVLL--SMPSGTGEV--RAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652
RD+K N+++ S+ E+ ++DFGL+ K S + GT ++APE+
Sbjct: 237 RDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQ--SRSEAMLQATCGTPIYMAPEV 294
Query: 653 INGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
I+ + DI+S+G V Y +L +G+ PF
Sbjct: 295 ISAHDYSQQCDIWSIGVVMYMLL-RGEPPF 323
>U63973-1|AAB05929.1| 563|Homo sapiens rhodopsin kinase protein.
Length = 563
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/102 (43%), Positives = 60/102 (58%), Gaps = 9/102 (8%)
Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640
Q GL HLH IV+RD+KP NVLL G VR ISD GL+ +L G+ S+ G
Sbjct: 300 QIICGLEHLHQRRIVYRDLKPENVLLD---NDGNVR--ISDLGLAVELLDGQ---SKTKG 351
Query: 641 VTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
GT G++APE++ GE S+D F+LG Y +++ + PF
Sbjct: 352 YAGTPGFMAPELLQGEEYDFSVDYFALGVTLYEMIA-ARGPF 392
>L77503-1|AAG50439.1| 563|Homo sapiens rhodopsin kinase protein.
Length = 563
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/102 (43%), Positives = 60/102 (58%), Gaps = 9/102 (8%)
Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640
Q GL HLH IV+RD+KP NVLL G VR ISD GL+ +L G+ S+ G
Sbjct: 300 QIICGLEHLHQRRIVYRDLKPENVLLD---NDGNVR--ISDLGLAVELLDGQ---SKTKG 351
Query: 641 VTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
GT G++APE++ GE S+D F+LG Y +++ + PF
Sbjct: 352 YAGTPGFMAPELLQGEEYDFSVDYFALGVTLYEMIA-ARGPF 392
>L77502-1|AAT00534.2| 563|Homo sapiens rhodopsin kinase protein.
Length = 563
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/102 (43%), Positives = 60/102 (58%), Gaps = 9/102 (8%)
Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640
Q GL HLH IV+RD+KP NVLL G VR ISD GL+ +L G+ S+ G
Sbjct: 300 QIICGLEHLHQRRIVYRDLKPENVLLD---NDGNVR--ISDLGLAVELLDGQ---SKTKG 351
Query: 641 VTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
GT G++APE++ GE S+D F+LG Y +++ + PF
Sbjct: 352 YAGTPGFMAPELLQGEEYDFSVDYFALGVTLYEMIA-ARGPF 392
>AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinase B
(RSK-B) protein.
Length = 772
Score = 73.7 bits (173), Expect = 3e-12
Identities = 57/181 (31%), Positives = 92/181 (50%), Gaps = 8/181 (4%)
Query: 504 RDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDY 562
++ AVK L REVA LR +H +VV + D+ Y+ LEL L ++
Sbjct: 435 QEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEH 494
Query: 563 VEKKLNFECKIDSVEILRQATMGLSHLH-SMDIVHRDVKPHNVLLSMPSGTGEVRAMISD 621
+ KK +F + ++ +ILR +S +H +VHRD+KP N+L + + V+ I D
Sbjct: 495 IRKKRHFS-ESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVK--IID 551
Query: 622 FGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHP 681
FG + +L ++ T + APE++ + S D++SLG + Y +LS GQ P
Sbjct: 552 FGFA-RLRPQSPGVPMQTPCF-TLQYAAPELLAQQGYDESCDLWSLGVILYMMLS-GQVP 608
Query: 682 F 682
F
Sbjct: 609 F 609
Score = 50.4 bits (115), Expect = 3e-05
Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 9/103 (8%)
Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640
+ + L HLH + I++RD+K NVLL E +++DFGLSK+ R
Sbjct: 144 EIVLALEHLHKLGIIYRDLKLENVLLD-----SEGHIVLTDFGLSKEFLTEEK--ERTFS 196
Query: 641 VTGTDGWIAPEMINGER-TTTSIDIFSLGCVFYYVLSKGQHPF 682
GT ++APE+I + ++D +SLG + + +L+ G PF
Sbjct: 197 FCGTIEYMAPEIIRSKTGHGKAVDWWSLGILLFELLT-GASPF 238
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase
RLPK protein.
Length = 802
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/177 (27%), Positives = 92/177 (51%), Gaps = 8/177 (4%)
Query: 507 AVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEK 565
AVK + +E+ L+ + H ++V+ + D+ ++ +EL + L + ++K
Sbjct: 453 AVKIISKRMEANTQKEITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKK 512
Query: 566 KLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLS 625
K +F + ++ I+R+ +SH+H + +VHRD+KP N+L + + E++ I DFG +
Sbjct: 513 KKHFS-ETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIK--IIDFGFA 569
Query: 626 KKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
+ + T + APE++N S D++SLG + Y +LS GQ PF
Sbjct: 570 R---LKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCDLWSLGVILYTMLS-GQVPF 622
Score = 55.2 bits (127), Expect = 1e-06
Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 15/156 (9%)
Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640
+ + L HLH + I++RD+K N+LL G V +++DFGLSK+ R
Sbjct: 160 EIVLALEHLHKLGIIYRDIKLENILL---DSNGHV--VLTDFGLSKEFVADET--ERAYS 212
Query: 641 VTGTDGWIAPEMINGERT--TTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGD 696
GT ++AP+++ G + ++D +SLG + Y +L+ G PF QA I
Sbjct: 213 FCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLT-GASPFTVDGEKNSQAEI---S 268
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPC 732
+ + P+E + K LI+ ++ P R C
Sbjct: 269 RRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGC 304
>AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and
stress-activated protein kinase-2 protein.
Length = 705
Score = 73.7 bits (173), Expect = 3e-12
Identities = 57/181 (31%), Positives = 92/181 (50%), Gaps = 8/181 (4%)
Query: 504 RDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDY 562
++ AVK L REVA LR +H +VV + D+ Y+ LEL L ++
Sbjct: 413 QEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEH 472
Query: 563 VEKKLNFECKIDSVEILRQATMGLSHLH-SMDIVHRDVKPHNVLLSMPSGTGEVRAMISD 621
+ KK +F + ++ +ILR +S +H +VHRD+KP N+L + + V+ I D
Sbjct: 473 IRKKRHFS-ESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVK--IID 529
Query: 622 FGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHP 681
FG + +L ++ T + APE++ + S D++SLG + Y +LS GQ P
Sbjct: 530 FGFA-RLRPQSPGVPMQTPCF-TLQYAAPELLAQQGYDESCDLWSLGVILYMMLS-GQVP 586
Query: 682 F 682
F
Sbjct: 587 F 587
Score = 50.4 bits (115), Expect = 3e-05
Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 9/103 (8%)
Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640
+ + L HLH + I++RD+K NVLL E +++DFGLSK+ R
Sbjct: 128 EIVLALEHLHKLGIIYRDLKLENVLLD-----SEGHIVLTDFGLSKEFLTEEK--ERTFS 180
Query: 641 VTGTDGWIAPEMINGER-TTTSIDIFSLGCVFYYVLSKGQHPF 682
GT ++APE+I + ++D +SLG + + +L+ G PF
Sbjct: 181 FCGTIEYMAPEIIRSKTGHGKAVDWWSLGILLFELLT-GASPF 222
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/177 (27%), Positives = 92/177 (51%), Gaps = 8/177 (4%)
Query: 507 AVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEK 565
AVK + +E+ L+ + H ++V+ + D+ ++ +EL + L + ++K
Sbjct: 453 AVKIISKRMEANTQKEITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKK 512
Query: 566 KLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLS 625
K +F + ++ I+R+ +SH+H + +VHRD+KP N+L + + E++ I DFG +
Sbjct: 513 KKHFS-ETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIK--IIDFGFA 569
Query: 626 KKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
+ + T + APE++N S D++SLG + Y +LS GQ PF
Sbjct: 570 R---LKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCDLWSLGVILYTMLS-GQVPF 622
Score = 55.2 bits (127), Expect = 1e-06
Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 15/156 (9%)
Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640
+ + L HLH + I++RD+K N+LL G V +++DFGLSK+ R
Sbjct: 160 EIVLALEHLHKLGIIYRDIKLENILL---DSNGHV--VLTDFGLSKEFVADET--ERAYS 212
Query: 641 VTGTDGWIAPEMINGERT--TTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGD 696
GT ++AP+++ G + ++D +SLG + Y +L+ G PF QA I
Sbjct: 213 FCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLT-GASPFTVDGEKNSQAEI---S 268
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPC 732
+ + P+E + K LI+ ++ P R C
Sbjct: 269 RRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGC 304
>U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein
kinase protein.
Length = 859
Score = 73.3 bits (172), Expect = 4e-12
Identities = 69/252 (27%), Positives = 116/252 (46%), Gaps = 19/252 (7%)
Query: 485 QVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERD 544
Q +G G +G V+ G F +VAVK++ + ++ LR+ H +++ +
Sbjct: 129 QWVGSGAQGA-VFLGRFHGEEVAVKKVRD----LKETDIKHLRKLK-HPNIITFKGVCTQ 182
Query: 545 KQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNV 604
I +E C+ V + V+ G+++LH I+HRD+K N+
Sbjct: 183 APCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNM 242
Query: 605 LLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDI 664
L+ T + ISDFG SK+L+ S + GT W+APE+I E + +DI
Sbjct: 243 LI-----TYDDVVKISDFGTSKELS----DKSTKMSFAGTVAWMAPEVIRNEPVSEKVDI 293
Query: 665 FSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISA 724
+S G V + +L+ G+ P+ DV ++ + + L +P KIL+R ++
Sbjct: 294 WSFGVVLWELLT-GEIPYKDV---DSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNS 349
Query: 725 KPSARPPCETIL 736
KP RP IL
Sbjct: 350 KPRNRPSFRQIL 361
>BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 73.3 bits (172), Expect = 4e-12
Identities = 77/278 (27%), Positives = 135/278 (48%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ ++V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-SYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D + E +I ++ L++ GL +LHS +HRD+
Sbjct: 88 SYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATM--LKEILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S G+V+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEQGDVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIQQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L+KG+ P D+ + L N L E K I
Sbjct: 198 SKADIWSLG-ITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTES----FKEFID 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDR 290
>BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein.
Length = 567
Score = 73.3 bits (172), Expect = 4e-12
Identities = 69/252 (27%), Positives = 116/252 (46%), Gaps = 19/252 (7%)
Query: 485 QVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERD 544
Q +G G +G V+ G F +VAVK++ + ++ LR+ H +++ +
Sbjct: 162 QWVGSGAQGA-VFLGRFHGEEVAVKKVRD----LKETDIKHLRKLK-HPNIITFKGVCTQ 215
Query: 545 KQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNV 604
I +E C+ V + V+ G+++LH I+HRD+K N+
Sbjct: 216 APCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNM 275
Query: 605 LLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDI 664
L+ T + ISDFG SK+L+ S + GT W+APE+I E + +DI
Sbjct: 276 LI-----TYDDVVKISDFGTSKELS----DKSTKMSFAGTVAWMAPEVIRNEPVSEKVDI 326
Query: 665 FSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISA 724
+S G V + +L+ G+ P+ DV ++ + + L +P KIL+R ++
Sbjct: 327 WSFGVVLWELLT-GEIPYKDV---DSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNS 382
Query: 725 KPSARPPCETIL 736
KP RP IL
Sbjct: 383 KPRNRPSFRQIL 394
>AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle
preferentially expressed protein protein.
Length = 3094
Score = 73.3 bits (172), Expect = 4e-12
Identities = 60/223 (26%), Positives = 101/223 (45%), Gaps = 10/223 (4%)
Query: 519 ADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEI 578
A RE LL H V+ ++ ++ I ELC+ L + + +K C+ +
Sbjct: 1513 ARREARLLARLQ-HDCVLYFHEAFERRRGLVIVTELCTEELLERIARKPTV-CESEIRAY 1570
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ G+ +LH ++H DVKP N LL GE + I DFG +++L G + +
Sbjct: 1571 MRQVLEGIHYLHQSHVLHLDVKPEN-LLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQ- 1628
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYN 698
GT ++APE++N + DI+ +G V + L+ G PF R + +YN
Sbjct: 1629 ---YGTPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLT-GISPFVGENDRTTLMNIRNYN 1684
Query: 699 LDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+ + LI+ ++ + RP E L++P F
Sbjct: 1685 VAFEETTFLSLSREARGFLIKVLVQDR--LRPTAEETLEHPWF 1725
Score = 58.0 bits (134), Expect = 2e-07
Identities = 46/159 (28%), Positives = 76/159 (47%), Gaps = 14/159 (8%)
Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633
D + Q GL +LH ++H D+KP N+LL+ + I DFG ++ N
Sbjct: 2932 DVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLLAPDNAL-----KIVDFGSAQPYN--PQ 2984
Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQAN 691
+ TGT ++APEM+ GE ++ DI+ G + Y +LS G+ PF D +A
Sbjct: 2985 ALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGVLTYIMLS-GRSPFYEPDPQETEAR 3043
Query: 692 ILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARP 730
I+ G ++ L + + +R ++S P +RP
Sbjct: 3044 IVGGRFDAFQLYPNTSQS----ATLFLRKVLSVHPWSRP 3078
>AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ90523 fis, clone NT2RP4000634, highly similar to
Homo sapiens mitogen-activated protein kinase kinase
kinase ).
Length = 423
Score = 73.3 bits (172), Expect = 4e-12
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 8/158 (5%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSV--EIL 579
E+ LL+ H +V+YY RD Q + +++ + ++ + ++V +
Sbjct: 210 EIQLLKNL-LHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYT 268
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ G+ +LHS IVHRD+K N+L TG V+ + DFG SK+L +S +
Sbjct: 269 RQILEGVHYLHSNMIVHRDIKGANILRD---STGNVK--LGDFGASKRLQTICLSGTGMK 323
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSK 677
VTGT W++PE+I+GE DI+S+ C +L++
Sbjct: 324 SVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTE 361
>AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase
protein.
Length = 859
Score = 73.3 bits (172), Expect = 4e-12
Identities = 69/252 (27%), Positives = 116/252 (46%), Gaps = 19/252 (7%)
Query: 485 QVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERD 544
Q +G G +G V+ G F +VAVK++ + ++ LR+ H +++ +
Sbjct: 129 QWVGSGAQGA-VFLGRFHGEEVAVKKVRD----LKETDIKHLRKLK-HPNIITFKGVCTQ 182
Query: 545 KQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNV 604
I +E C+ V + V+ G+++LH I+HRD+K N+
Sbjct: 183 APCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNM 242
Query: 605 LLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDI 664
L+ T + ISDFG SK+L+ S + GT W+APE+I E + +DI
Sbjct: 243 LI-----TYDDVVKISDFGTSKELS----DKSTKMSFAGTVAWMAPEVIRNEPVSEKVDI 293
Query: 665 FSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISA 724
+S G V + +L+ G+ P+ DV ++ + + L +P KIL+R ++
Sbjct: 294 WSFGVVLWELLT-GEIPYKDV---DSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNS 349
Query: 725 KPSARPPCETIL 736
KP RP IL
Sbjct: 350 KPRNRPSFRQIL 361
>AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein.
Length = 270
Score = 73.3 bits (172), Expect = 4e-12
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 8/158 (5%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSV--EIL 579
E+ LL+ H +V+YY RD Q + +++ + ++ + ++V +
Sbjct: 57 EIQLLKNL-LHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYT 115
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ G+ +LHS IVHRD+K N+L TG V+ + DFG SK+L +S +
Sbjct: 116 RQILEGVHYLHSNMIVHRDIKGANILRD---STGNVK--LGDFGASKRLQTICLSGTGMK 170
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSK 677
VTGT W++PE+I+GE DI+S+ C +L++
Sbjct: 171 SVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTE 208
>AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b
variant protein.
Length = 621
Score = 73.3 bits (172), Expect = 4e-12
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 8/158 (5%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSV--EIL 579
E+ LL+ H +V+YY RD Q + +++ + ++ + ++V +
Sbjct: 408 EIQLLKNL-LHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYT 466
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
RQ G+ +LHS IVHRD+K N+L TG V+ + DFG SK+L +S +
Sbjct: 467 RQILEGVHYLHSNMIVHRDIKGANILRD---STGNVK--LGDFGASKRLQTICLSGTGMK 521
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSK 677
VTGT W++PE+I+GE DI+S+ C +L++
Sbjct: 522 SVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTE 559
>AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein.
Length = 2242
Score = 73.3 bits (172), Expect = 4e-12
Identities = 60/223 (26%), Positives = 101/223 (45%), Gaps = 10/223 (4%)
Query: 519 ADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEI 578
A RE LL H V+ ++ ++ I ELC+ L + + +K C+ +
Sbjct: 661 ARREARLLARLQ-HDCVLYFHEAFERRRGLVIVTELCTEELLERIARKPTV-CESEIRAY 718
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
+RQ G+ +LH ++H DVKP N LL GE + I DFG +++L G + +
Sbjct: 719 MRQVLEGIHYLHQSHVLHLDVKPEN-LLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQ- 776
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYN 698
GT ++APE++N + DI+ +G V + L+ G PF R + +YN
Sbjct: 777 ---YGTPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLT-GISPFVGENDRTTLMNIRNYN 832
Query: 699 LDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
+ + LI+ ++ + RP E L++P F
Sbjct: 833 VAFEETTFLSLSREARGFLIKVLVQDR--LRPTAEETLEHPWF 873
Score = 58.0 bits (134), Expect = 2e-07
Identities = 46/159 (28%), Positives = 76/159 (47%), Gaps = 14/159 (8%)
Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633
D + Q GL +LH ++H D+KP N+LL+ + I DFG ++ N
Sbjct: 2080 DVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLLAPDNAL-----KIVDFGSAQPYN--PQ 2132
Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQAN 691
+ TGT ++APEM+ GE ++ DI+ G + Y +LS G+ PF D +A
Sbjct: 2133 ALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGVLTYIMLS-GRSPFYEPDPQETEAR 2191
Query: 692 ILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARP 730
I+ G ++ L + + +R ++S P +RP
Sbjct: 2192 IVGGRFDAFQLYPNTSQS----ATLFLRKVLSVHPWSRP 2226
>X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein
kinase protein.
Length = 305
Score = 72.9 bits (171), Expect = 5e-12
Identities = 46/161 (28%), Positives = 91/161 (56%), Gaps = 11/161 (6%)
Query: 519 ADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVE- 577
A RE++LL+E H ++VR +++ Y+ E S L+ Y++ E + ++
Sbjct: 48 AIREISLLKELK-HPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKS 106
Query: 578 ILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSR 637
L Q G+S HS ++HRD+KP N+L+ + G ++ ++DFGL++ + +++
Sbjct: 107 YLFQLLQGVSFCHSHRVIHRDLKPQNLLI---NELGAIK--LADFGLARAFGVPLRTYTH 161
Query: 638 RSGVTGTDGWIAPEMINGER-TTTSIDIFSLGCVFYYVLSK 677
T + APE++ G + TT++DI+S+GC+F ++++
Sbjct: 162 E---VVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTR 199
>AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase 3
protein.
Length = 305
Score = 72.9 bits (171), Expect = 5e-12
Identities = 46/161 (28%), Positives = 91/161 (56%), Gaps = 11/161 (6%)
Query: 519 ADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVE- 577
A RE++LL+E H ++VR +++ Y+ E S L+ Y++ E + ++
Sbjct: 48 AIREISLLKELK-HPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKS 106
Query: 578 ILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSR 637
L Q G+S HS ++HRD+KP N+L+ + G ++ ++DFGL++ + +++
Sbjct: 107 YLFQLLQGVSFCHSHRVIHRDLKPQNLLI---NELGAIK--LADFGLARAFGVPLRTYTH 161
Query: 638 RSGVTGTDGWIAPEMINGER-TTTSIDIFSLGCVFYYVLSK 677
T + APE++ G + TT++DI+S+GC+F ++++
Sbjct: 162 E---VVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTR 199
>AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 72.9 bits (171), Expect = 5e-12
Identities = 53/180 (29%), Positives = 93/180 (51%), Gaps = 13/180 (7%)
Query: 578 ILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSR 637
ILR+ GL +LHS +HRD+K NVLL S GEV+ ++DFG++ +L ++ +
Sbjct: 41 ILREILKGLDYLHSEKKIHRDIKAANVLL---SEHGEVK--LADFGVAGQLTDTQI---K 92
Query: 638 RSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY 697
R+ GT W+APE+I + DI+SLG + L++G+ P ++ + L
Sbjct: 93 RNTFVGTPFWMAPEVIKQSAYDSKADIWSLG-ITAIELARGEPPHSELHPMKVLFLIPKN 151
Query: 698 NLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
N L+ + +K + A ++ +PS RP + +LK+ ++L ++ D+
Sbjct: 152 NPPTLEGNYSKP----LKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR 207
>AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 72.9 bits (171), Expect = 5e-12
Identities = 53/180 (29%), Positives = 93/180 (51%), Gaps = 13/180 (7%)
Query: 578 ILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSR 637
ILR+ GL +LHS +HRD+K NVLL S GEV+ ++DFG++ +L ++ +
Sbjct: 41 ILREILKGLDYLHSEKKIHRDIKAANVLL---SEHGEVK--LADFGVAGQLTDTQI---K 92
Query: 638 RSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY 697
R+ GT W+APE+I + DI+SLG + L++G+ P ++ + L
Sbjct: 93 RNTFVGTPFWMAPEVIKQSAYDSKADIWSLG-ITAIELARGEPPHSELHPMKVLFLIPKN 151
Query: 698 NLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
N L+ + +K + A ++ +PS RP + +LK+ ++L ++ D+
Sbjct: 152 NPPTLEGNYSKP----LKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR 207
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 72.9 bits (171), Expect = 5e-12
Identities = 69/223 (30%), Positives = 109/223 (48%), Gaps = 23/223 (10%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+RE+A+L+ + H HV++ + +K++ Y+ LE S L DY+ KK K ++ +
Sbjct: 110 EREIAILKLIE-HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK-EARKF 167
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
RQ L HS I HRD+KP N+LL + +R I+DFG++ L +G S
Sbjct: 168 FRQIISALDFCHSHSICHRDLKPENLLLDEKN---NIR--IADFGMA-SLQVGD---SLL 218
Query: 639 SGVTGTDGWIAPEMINGER-TTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTG 695
G+ + PE+I GE+ D++S G V + L G PF D RQ + G
Sbjct: 219 ETSCGSPHYACPEVIRGEKYDGRKADVWSCG-VILFALLVGALPFDDDNLRQLLEKVKRG 277
Query: 696 DYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKY 738
+++ H I P+ + L+R MI + R E I K+
Sbjct: 278 VFHMPHF--IPPD-----CQSLLRGMIEVDAARRLTLEHIQKH 313
>BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 72.5 bits (170), Expect = 7e-12
Identities = 57/181 (31%), Positives = 99/181 (54%), Gaps = 12/181 (6%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILR 580
E+++LR +H ++V+ + Y+ +EL + L D + + +F + D+V IL+
Sbjct: 108 ELSVLRRV-SHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTER-DAVRILQ 165
Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS-RRS 639
G+ +LH++ I HR++KP N+L P E + +I+DFGL+ G+ S
Sbjct: 166 MVADGIRYLHALQITHRNLKPENLLYYHPG--EESKILITDFGLAYS---GKKSGDWTMK 220
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD--VLRRQANILTGDY 697
+ GT +IAPE++ + T+++D+++LG + Y +LS G PF D R IL G Y
Sbjct: 221 TLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLS-GFLPFDDESQTRLYRKILKGKY 279
Query: 698 N 698
N
Sbjct: 280 N 280
>BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 72.5 bits (170), Expect = 7e-12
Identities = 57/181 (31%), Positives = 99/181 (54%), Gaps = 12/181 (6%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILR 580
E+++LR +H ++V+ + Y+ +EL + L D + + +F + D+V IL+
Sbjct: 108 ELSVLRRV-SHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTER-DAVRILQ 165
Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS-RRS 639
G+ +LH++ I HR++KP N+L P E + +I+DFGL+ G+ S
Sbjct: 166 MVADGIRYLHALQITHRNLKPENLLYYHPG--EESKILITDFGLAYS---GKKSGDWTMK 220
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD--VLRRQANILTGDY 697
+ GT +IAPE++ + T+++D+++LG + Y +LS G PF D R IL G Y
Sbjct: 221 TLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLS-GFLPFDDESQTRLYRKILKGKY 279
Query: 698 N 698
N
Sbjct: 280 N 280
>BC032787-1|AAH32787.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 72.5 bits (170), Expect = 7e-12
Identities = 61/223 (27%), Positives = 108/223 (48%), Gaps = 16/223 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+L++ H ++V Y+ ++L S L D + ++ + K D+ +
Sbjct: 66 ENEIAVLKKIK-HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEK-DASLV 123
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
++Q + +LH IVHRD+KP N+L P ++ MI+DFGLSK G +S +
Sbjct: 124 IQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKI--MITDFGLSKMEQNGIMSTA-- 179
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGD 696
GT G++APE++ + + ++D +S+G V Y+L G PF + + I G
Sbjct: 180 ---CGTPGYVAPEVLAQKPYSKAVDCWSIG-VITYILLCGYPPFYEETESKLFEKIKEGY 235
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y + ++ K I ++ P+ R CE L +P
Sbjct: 236 Y---EFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHP 275
>AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein.
Length = 460
Score = 72.5 bits (170), Expect = 7e-12
Identities = 61/223 (27%), Positives = 108/223 (48%), Gaps = 16/223 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+L++ H ++V Y+ ++L S L D + ++ + K D+ +
Sbjct: 66 ENEIAVLKKIK-HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEK-DASLV 123
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
++Q + +LH IVHRD+KP N+L P ++ MI+DFGLSK G +S +
Sbjct: 124 IQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKI--MITDFGLSKMEQNGIMSTA-- 179
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGD 696
GT G++APE++ + + ++D +S+G V Y+L G PF + + I G
Sbjct: 180 ---CGTPGYVAPEVLAQKPYSKAVDCWSIG-VITYILLCGYPPFYEETESKLFEKIKEGY 235
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y + ++ K I ++ P+ R CE L +P
Sbjct: 236 Y---EFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHP 275
>AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase
PSKH2 protein.
Length = 385
Score = 72.5 bits (170), Expect = 7e-12
Identities = 57/181 (31%), Positives = 99/181 (54%), Gaps = 12/181 (6%)
Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILR 580
E+++LR +H ++V+ + Y+ +EL + L D + + +F + D+V IL+
Sbjct: 108 ELSVLRRV-SHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTER-DAVRILQ 165
Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS-RRS 639
G+ +LH++ I HR++KP N+L P E + +I+DFGL+ G+ S
Sbjct: 166 MVADGIRYLHALQITHRNLKPENLLYYHPG--EESKILITDFGLAYS---GKKSGDWTMK 220
Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD--VLRRQANILTGDY 697
+ GT +IAPE++ + T+++D+++LG + Y +LS G PF D R IL G Y
Sbjct: 221 TLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLS-GFLPFDDESQTRLYRKILKGKY 279
Query: 698 N 698
N
Sbjct: 280 N 280
>AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein
protein.
Length = 481
Score = 72.5 bits (170), Expect = 7e-12
Identities = 61/223 (27%), Positives = 108/223 (48%), Gaps = 16/223 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+L++ H ++V Y+ ++L S L D + ++ + K D+ +
Sbjct: 71 ENEIAVLKKIK-HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEK-DASLV 128
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
++Q + +LH IVHRD+KP N+L P ++ MI+DFGLSK G +S +
Sbjct: 129 IQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKI--MITDFGLSKMEQNGIMSTA-- 184
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGD 696
GT G++APE++ + + ++D +S+G V Y+L G PF + + I G
Sbjct: 185 ---CGTPGYVAPEVLAQKPYSKAVDCWSIG-VITYILLCGYPPFYEETESKLFEKIKEGY 240
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y + ++ K I ++ P+ R CE L +P
Sbjct: 241 Y---EFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHP 280
>AL023754-3|CAI19991.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 72.5 bits (170), Expect = 7e-12
Identities = 61/223 (27%), Positives = 108/223 (48%), Gaps = 16/223 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+L++ H ++V Y+ ++L S L D + ++ + K D+ +
Sbjct: 66 ENEIAVLKKIK-HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEK-DASLV 123
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
++Q + +LH IVHRD+KP N+L P ++ MI+DFGLSK G +S +
Sbjct: 124 IQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKI--MITDFGLSKMEQNGIMSTA-- 179
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGD 696
GT G++APE++ + + ++D +S+G V Y+L G PF + + I G
Sbjct: 180 ---CGTPGYVAPEVLAQKPYSKAVDCWSIG-VITYILLCGYPPFYEETESKLFEKIKEGY 235
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y + ++ K I ++ P+ R CE L +P
Sbjct: 236 Y---EFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHP 275
>AF428261-1|AAL28100.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase I gamma
protein.
Length = 476
Score = 72.5 bits (170), Expect = 7e-12
Identities = 61/223 (27%), Positives = 108/223 (48%), Gaps = 16/223 (7%)
Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578
+ E+A+L++ H ++V Y+ ++L S L D + ++ + K D+ +
Sbjct: 66 ENEIAVLKKIK-HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEK-DASLV 123
Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638
++Q + +LH IVHRD+KP N+L P ++ MI+DFGLSK G +S +
Sbjct: 124 IQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKI--MITDFGLSKMEQNGIMSTA-- 179
Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGD 696
GT G++APE++ + + ++D +S+G V Y+L G PF + + I G
Sbjct: 180 ---CGTPGYVAPEVLAQKPYSKAVDCWSIG-VITYILLCGYPPFYEETESKLFEKIKEGY 235
Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739
Y + ++ K I ++ P+ R CE L +P
Sbjct: 236 Y---EFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHP 275
>X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase
protein.
Length = 387
Score = 72.1 bits (169), Expect = 9e-12
Identities = 60/230 (26%), Positives = 107/230 (46%), Gaps = 23/230 (10%)
Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEIL 579
+EV +LR+ H ++++ T F ++ +L L DY+ +K+ K ++ +I+
Sbjct: 73 KEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEK-ETRKIM 131
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
R + LH ++IVHRD+KP N+LL + ++DFG S +L G R
Sbjct: 132 RALLEVICTLHKLNIVHRDLKPENILLD-----DNMNIKLTDFGFSCQLEPG----ERLR 182
Query: 640 GVTGTDGWIAPEMINGERTT------TSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQAN 691
V GT ++APE+I +D++S G + Y +L+ G PF +
Sbjct: 183 EVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLA-GSPPFWHRKQMLMLRM 241
Query: 692 ILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
I++G+Y + ++ +K L+ + +P R E L +P F
Sbjct: 242 IMSGNYQFGSPEW---DDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF 288
>U50648-1|AAC50768.1| 551|Homo sapiens interferon-inducible
RNA-dependent protein kinase protein.
Length = 551
Score = 72.1 bits (169), Expect = 9e-12
Identities = 55/198 (27%), Positives = 97/198 (48%), Gaps = 21/198 (10%)
Query: 549 YIALELCS-ATLQDYVEKKLNFEC-KIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLL 606
+I +E C TL+ ++EK+ + K+ ++E+ Q T G+ ++HS ++HRD+KP N+ L
Sbjct: 363 FIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFL 422
Query: 607 SMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFS 666
T +V+ I DFGL L + +R+ GT +++PE I+ + +D+++
Sbjct: 423 ---VDTKQVK--IGDFGLVTSLK----NDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYA 473
Query: 667 LGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKP 726
LG + +L F T + D D I+ + K L++ ++S KP
Sbjct: 474 LGLILAELLHVCDTAFE----------TSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKP 523
Query: 727 SARPPCETILKYPMFWCK 744
RP IL+ W K
Sbjct: 524 EDRPNTSEILRTLTVWKK 541
>M85294-1|AAA18253.1| 551|Homo sapiens P1/eIF-2a protein kinase
protein.
Length = 551
Score = 72.1 bits (169), Expect = 9e-12
Identities = 55/198 (27%), Positives = 97/198 (48%), Gaps = 21/198 (10%)
Query: 549 YIALELCS-ATLQDYVEKKLNFEC-KIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLL 606
+I +E C TL+ ++EK+ + K+ ++E+ Q T G+ ++HS ++HRD+KP N+ L
Sbjct: 363 FIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFL 422
Query: 607 SMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFS 666
T +V+ I DFGL L + +R+ GT +++PE I+ + +D+++
Sbjct: 423 ---VDTKQVK--IGDFGLVTSLK----NDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYA 473
Query: 667 LGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKP 726
LG + +L F T + D D I+ + K L++ ++S KP
Sbjct: 474 LGLILAELLHVCDTAFE----------TSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKP 523
Query: 727 SARPPCETILKYPMFWCK 744
RP IL+ W K
Sbjct: 524 EDRPNTSEILRTLTVWKK 541
>M35663-1|AAA36409.1| 551|Homo sapiens protein ( Human p68 kinase
mRNA, complete cds. ).
Length = 551
Score = 72.1 bits (169), Expect = 9e-12
Identities = 55/198 (27%), Positives = 97/198 (48%), Gaps = 21/198 (10%)
Query: 549 YIALELCS-ATLQDYVEKKLNFEC-KIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLL 606
+I +E C TL+ ++EK+ + K+ ++E+ Q T G+ ++HS ++HRD+KP N+ L
Sbjct: 363 FIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFL 422
Query: 607 SMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFS 666
T +V+ I DFGL L + +R+ GT +++PE I+ + +D+++
Sbjct: 423 ---VDTKQVK--IGDFGLVTSLK----NDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYA 473
Query: 667 LGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKP 726
LG + +L F T + D D I+ + K L++ ++S KP
Sbjct: 474 LGLILAELLHVCDTAFE----------TSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKP 523
Query: 727 SARPPCETILKYPMFWCK 744
RP IL+ W K
Sbjct: 524 EDRPNTSEILRTLTVWKK 541
>BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related
kinase protein.
Length = 416
Score = 72.1 bits (169), Expect = 9e-12
Identities = 76/278 (27%), Positives = 135/278 (48%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ ++V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-SYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D + E +I ++ L++ GL +LHS +HRD+
Sbjct: 88 SYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATM--LKEILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S G+V+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEQGDVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIQQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L+KG+ P D+ + L N L + K I
Sbjct: 198 SKADIWSLG-ITAIELAKGEPPNSDMHPMRVLFLIPKNN----PPTLVGDFTKSFKEFID 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDR 290
>BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 72.1 bits (169), Expect = 9e-12
Identities = 76/278 (27%), Positives = 135/278 (48%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ ++V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-SYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D + E +I ++ L++ GL +LHS +HRD+
Sbjct: 88 SYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATM--LKEILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S G+V+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEQGDVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIQQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L+KG+ P D+ + L N L + K I
Sbjct: 198 SKADIWSLG-ITAIELAKGEPPNSDMHPMRVLFLIPKNN----PPTLVGDFTKSFKEFID 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDR 290
>BC101475-1|AAI01476.1| 551|Homo sapiens eukaryotic translation
initiation factor 2-alpha kinase 2 protein.
Length = 551
Score = 72.1 bits (169), Expect = 9e-12
Identities = 55/198 (27%), Positives = 97/198 (48%), Gaps = 21/198 (10%)
Query: 549 YIALELCS-ATLQDYVEKKLNFEC-KIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLL 606
+I +E C TL+ ++EK+ + K+ ++E+ Q T G+ ++HS ++HRD+KP N+ L
Sbjct: 363 FIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFL 422
Query: 607 SMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFS 666
T +V+ I DFGL L + +R+ GT +++PE I+ + +D+++
Sbjct: 423 ---VDTKQVK--IGDFGLVTSLK----NDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYA 473
Query: 667 LGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKP 726
LG + +L F T + D D I+ + K L++ ++S KP
Sbjct: 474 LGLILAELLHVCDTAFE----------TSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKP 523
Query: 727 SARPPCETILKYPMFWCK 744
RP IL+ W K
Sbjct: 524 EDRPNTSEILRTLTVWKK 541
>BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 72.1 bits (169), Expect = 9e-12
Identities = 76/278 (27%), Positives = 135/278 (48%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ ++V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-SYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D + E +I ++ L++ GL +LHS +HRD+
Sbjct: 88 SYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATM--LKEILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S G+V+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEQGDVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIQQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L+KG+ P D+ + L N L + K I
Sbjct: 198 SKADIWSLG-ITAIELAKGEPPNSDMHPMRVLFLIPKNN----PPTLVGDFTKSFKEFID 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDR 290
>BC093676-1|AAH93676.1| 551|Homo sapiens eukaryotic translation
initiation factor 2-alpha kinase 2 protein.
Length = 551
Score = 72.1 bits (169), Expect = 9e-12
Identities = 55/198 (27%), Positives = 97/198 (48%), Gaps = 21/198 (10%)
Query: 549 YIALELCS-ATLQDYVEKKLNFEC-KIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLL 606
+I +E C TL+ ++EK+ + K+ ++E+ Q T G+ ++HS ++HRD+KP N+ L
Sbjct: 363 FIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFL 422
Query: 607 SMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFS 666
T +V+ I DFGL L + +R+ GT +++PE I+ + +D+++
Sbjct: 423 ---VDTKQVK--IGDFGLVTSLK----NDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYA 473
Query: 667 LGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKP 726
LG + +L F T + D D I+ + K L++ ++S KP
Sbjct: 474 LGLILAELLHVCDTAFE----------TSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKP 523
Query: 727 SARPPCETILKYPMFWCK 744
RP IL+ W K
Sbjct: 524 EDRPNTSEILRTLTVWKK 541
>BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 72.1 bits (169), Expect = 9e-12
Identities = 60/230 (26%), Positives = 107/230 (46%), Gaps = 23/230 (10%)
Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEIL 579
+EV +LR+ H ++++ T F ++ +L L DY+ +K+ K ++ +I+
Sbjct: 73 KEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEK-ETRKIM 131
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
R + LH ++IVHRD+KP N+LL + ++DFG S +L G R
Sbjct: 132 RALLEVICTLHKLNIVHRDLKPENILLD-----DNMNIKLTDFGFSCQLEPG----ERLR 182
Query: 640 GVTGTDGWIAPEMINGERTT------TSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQAN 691
V GT ++APE+I +D++S G + Y +L+ G PF +
Sbjct: 183 EVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLA-GSPPFWHRKQMLMLRM 241
Query: 692 ILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
I++G+Y + ++ +K L+ + +P R E L +P F
Sbjct: 242 IMSGNYQFGSPEW---DDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF 288
>BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 72.1 bits (169), Expect = 9e-12
Identities = 60/230 (26%), Positives = 107/230 (46%), Gaps = 23/230 (10%)
Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEIL 579
+EV +LR+ H ++++ T F ++ +L L DY+ +K+ K ++ +I+
Sbjct: 73 KEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEK-ETRKIM 131
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
R + LH ++IVHRD+KP N+LL + ++DFG S +L G R
Sbjct: 132 RALLEVICTLHKLNIVHRDLKPENILLD-----DNMNIKLTDFGFSCQLEPG----ERLR 182
Query: 640 GVTGTDGWIAPEMINGERTT------TSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQAN 691
V GT ++APE+I +D++S G + Y +L+ G PF +
Sbjct: 183 EVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLA-GSPPFWHRKQMLMLRM 241
Query: 692 ILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
I++G+Y + ++ +K L+ + +P R E L +P F
Sbjct: 242 IMSGNYQFGSPEW---DDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF 288
>BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 72.1 bits (169), Expect = 9e-12
Identities = 60/230 (26%), Positives = 107/230 (46%), Gaps = 23/230 (10%)
Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEIL 579
+EV +LR+ H ++++ T F ++ +L L DY+ +K+ K ++ +I+
Sbjct: 73 KEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEK-ETRKIM 131
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
R + LH ++IVHRD+KP N+LL + ++DFG S +L G R
Sbjct: 132 RALLEVICTLHKLNIVHRDLKPENILLD-----DNMNIKLTDFGFSCQLEPG----ERLR 182
Query: 640 GVTGTDGWIAPEMINGERTT------TSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQAN 691
V GT ++APE+I +D++S G + Y +L+ G PF +
Sbjct: 183 EVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLA-GSPPFWHRKQMLMLRM 241
Query: 692 ILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
I++G+Y + ++ +K L+ + +P R E L +P F
Sbjct: 242 IMSGNYQFGSPEW---DDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF 288
>BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 72.1 bits (169), Expect = 9e-12
Identities = 60/230 (26%), Positives = 107/230 (46%), Gaps = 23/230 (10%)
Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEIL 579
+EV +LR+ H ++++ T F ++ +L L DY+ +K+ K ++ +I+
Sbjct: 73 KEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEK-ETRKIM 131
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
R + LH ++IVHRD+KP N+LL + ++DFG S +L G R
Sbjct: 132 RALLEVICTLHKLNIVHRDLKPENILLD-----DNMNIKLTDFGFSCQLEPG----ERLR 182
Query: 640 GVTGTDGWIAPEMINGERTT------TSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQAN 691
V GT ++APE+I +D++S G + Y +L+ G PF +
Sbjct: 183 EVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLA-GSPPFWHRKQMLMLRM 241
Query: 692 ILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
I++G+Y + ++ +K L+ + +P R E L +P F
Sbjct: 242 IMSGNYQFGSPEW---DDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF 288
>BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 72.1 bits (169), Expect = 9e-12
Identities = 60/230 (26%), Positives = 107/230 (46%), Gaps = 23/230 (10%)
Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEIL 579
+EV +LR+ H ++++ T F ++ +L L DY+ +K+ K ++ +I+
Sbjct: 73 KEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEK-ETRKIM 131
Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639
R + LH ++IVHRD+KP N+LL + ++DFG S +L G R
Sbjct: 132 RALLEVICTLHKLNIVHRDLKPENILLD-----DNMNIKLTDFGFSCQLEPG----ERLR 182
Query: 640 GVTGTDGWIAPEMINGERTT------TSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQAN 691
V GT ++APE+I +D++S G + Y +L+ G PF +
Sbjct: 183 EVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLA-GSPPFWHRKQMLMLRM 241
Query: 692 ILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741
I++G+Y + ++ +K L+ + +P R E L +P F
Sbjct: 242 IMSGNYQFGSPEW---DDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF 288
>BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein.
Length = 247
Score = 72.1 bits (169), Expect = 9e-12
Identities = 72/223 (32%), Positives = 108/223 (48%), Gaps = 26/223 (11%)
Query: 480 TFQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLPECFTFADREVA--LLRESDAHAHVV 536
T++ + +GKG G F + + AVK L P + E +L+ H +VV
Sbjct: 20 TWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAGYNILKALSDHPNVV 79
Query: 537 RYYCT--ERDK---QFRYIALELCSA-TLQDYVEKKLNFECKIDS---VEILRQATMGLS 587
R+Y ++DK ++ LELCS ++ D V+ L ++ IL +A MGL
Sbjct: 80 RFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQ 139
Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647
HLH+ +HRDVK +N+LL+ G + DFG+S +L R RR+ GT W
Sbjct: 140 HLHNNKTIHRDVKGNNILLTTEGG-----VKLVDFGVSAQLTSTR---HRRNTSVGTPFW 191
Query: 648 IAPEMINGER---TT--TSIDIFSLGCVFYYVLSKGQHPFGDV 685
+APE+I E+ TT D +SLG + L G P D+
Sbjct: 192 MAPEVIACEQQLDTTYDARCDTWSLG-ITAIELGDGDPPLADL 233
>AY302136-1|AAP57628.1| 510|Homo sapiens interferon-inducible
double-stranded RNA-dependent protein kinase protein.
Length = 510
Score = 72.1 bits (169), Expect = 9e-12
Identities = 55/198 (27%), Positives = 97/198 (48%), Gaps = 21/198 (10%)
Query: 549 YIALELCS-ATLQDYVEKKLNFEC-KIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLL 606
+I +E C TL+ ++EK+ + K+ ++E+ Q T G+ ++HS ++HRD+KP N+ L
Sbjct: 322 FIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFL 381
Query: 607 SMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFS 666
T +V+ I DFGL L + +R+ GT +++PE I+ + +D+++
Sbjct: 382 ---VDTKQVK--IGDFGLVTSLK----NDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYA 432
Query: 667 LGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKP 726
LG + +L F T + D D I+ + K L++ ++S KP
Sbjct: 433 LGLILAELLHVCDTAFE----------TSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKP 482
Query: 727 SARPPCETILKYPMFWCK 744
RP IL+ W K
Sbjct: 483 EDRPNTSEILRTLTVWKK 500
>AY228338-1|AAO38055.1| 551|Homo sapiens protein kinase,
interferon-inducible double stranded RNA dependent
protein.
Length = 551
Score = 72.1 bits (169), Expect = 9e-12
Identities = 55/198 (27%), Positives = 97/198 (48%), Gaps = 21/198 (10%)
Query: 549 YIALELCS-ATLQDYVEKKLNFEC-KIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLL 606
+I +E C TL+ ++EK+ + K+ ++E+ Q T G+ ++HS ++HRD+KP N+ L
Sbjct: 363 FIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFL 422
Query: 607 SMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFS 666
T +V+ I DFGL L + +R+ GT +++PE I+ + +D+++
Sbjct: 423 ---VDTKQVK--IGDFGLVTSLK----NDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYA 473
Query: 667 LGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKP 726
LG + +L F T + D D I+ + K L++ ++S KP
Sbjct: 474 LGLILAELLHVCDTAFE----------TSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKP 523
Query: 727 SARPPCETILKYPMFWCK 744
RP IL+ W K
Sbjct: 524 EDRPNTSEILRTLTVWKK 541
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 72.1 bits (169), Expect = 9e-12
Identities = 68/231 (29%), Positives = 112/231 (48%), Gaps = 22/231 (9%)
Query: 481 FQTDQVLGKGCEGTF---VYRGTFDKRDVAV---KRLLPECFTFADREVALLRESDAHAH 534
++ ++ LGKG G V+ T K + + ++L +RE+A+L+ + H H
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE-HPH 77
Query: 535 VVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V++ + +K++ Y+ LE S L DY+ KK K ++ + RQ L HS
Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK-EARKFFRQIISALDFCHSHS 136
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I HRD+KP N+LL + +R I+DFG++ L +G S G+ + PE+I
Sbjct: 137 ICHRDLKPENLLLDEKN---NIR--IADFGMA-SLQVGD---SLLETSCGSPHYACPEVI 187
Query: 654 NGER-TTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDH 701
GE+ D++S G V + L G PF D RQ + G +++ H
Sbjct: 188 RGEKYDGRKADVWSCG-VILFALLVGALPFDDDNLRQLLEKVKRGVFHMPH 237
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 72.1 bits (169), Expect = 9e-12
Identities = 66/209 (31%), Positives = 100/209 (47%), Gaps = 19/209 (9%)
Query: 481 FQTDQVLGKGCEGT-FVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH----- 534
F+ + LGKG G ++ R K +A+K L A E L RE + +H
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 535 VVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
++R Y D Y+ LE T+ ++K F+ + + I A LS+ HS
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN-ALSYCHSKR 251
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
++HRD+KP N+LL GE++ I+DFG S SRR+ + GT ++ PEMI
Sbjct: 252 VIHRDIKPENLLLG---SAGELK--IADFGWSV-----HAPSSRRTTLCGTLDYLPPEMI 301
Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPF 682
G +D++SLG + Y L G+ PF
Sbjct: 302 EGRMHDEKVDLWSLGVLCYEFL-VGKPPF 329
>AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related
kinase (MST4) protein.
Length = 416
Score = 72.1 bits (169), Expect = 9e-12
Identities = 76/278 (27%), Positives = 135/278 (48%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ ++V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-SYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D + E +I ++ L++ GL +LHS +HRD+
Sbjct: 88 SYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATM--LKEILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S G+V+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEQGDVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIQQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L+KG+ P D+ + L N L + K I
Sbjct: 198 SKADIWSLG-ITAIELAKGEPPNSDMHPMRVLFLIPKNN----PPTLVGDFTKSFKEFID 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDR 290
>AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens
cDNA FLJ90669 fis, clone PLACE1005519, moderately
similar to Homo sapiens STE20-like kinase 3 (mst-3)
mRNA. ).
Length = 392
Score = 72.1 bits (169), Expect = 9e-12
Identities = 76/278 (27%), Positives = 135/278 (48%), Gaps = 24/278 (8%)
Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRL-LPEC---FTFADREVALLRESDAHAHVVRYYC 540
+GKG G V++G ++ VA+K + L E +E+ +L + D+ ++V +YY
Sbjct: 30 IGKGSFGE-VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-SYVTKYYG 87
Query: 541 TERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599
+ +I +E L + D + E +I ++ L++ GL +LHS +HRD+
Sbjct: 88 SYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATM--LKEILKGLDYLHSEKKIHRDI 145
Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659
K NVLL S G+V+ ++DFG++ +L ++ +R+ GT W+APE+I
Sbjct: 146 KAANVLL---SEQGDVK--LADFGVAGQLTDTQI---KRNTFVGTPFWMAPEVIQQSAYD 197
Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719
+ DI+SLG + L+KG+ P D+ + L N L + K I
Sbjct: 198 SKADIWSLG-ITAIELAKGEPPNSDMHPMRVLFLIPKNN----PPTLVGDFTKSFKEFID 252
Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757
A ++ PS RP + +LK+ ++L ++ D+
Sbjct: 253 ACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDR 290
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 72.1 bits (169), Expect = 9e-12
Identities = 68/231 (29%), Positives = 112/231 (48%), Gaps = 22/231 (9%)
Query: 481 FQTDQVLGKGCEGTF---VYRGTFDKRDVAV---KRLLPECFTFADREVALLRESDAHAH 534
++ ++ LGKG G V+ T K + + ++L +RE+A+L+ + H H
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE-HPH 77
Query: 535 VVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V++ + +K++ Y+ LE S L DY+ KK K ++ + RQ L HS
Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK-EARKFFRQIISALDFCHSHS 136
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I HRD+KP N+LL + +R I+DFG++ L +G S G+ + PE+I
Sbjct: 137 ICHRDLKPENLLLDEKN---NIR--IADFGMA-SLQVGD---SLLETSCGSPHYACPEVI 187
Query: 654 NGER-TTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDH 701
GE+ D++S G V + L G PF D RQ + G +++ H
Sbjct: 188 RGEKYDGRKADVWSCG-VILFALLVGALPFDDDNLRQLLEKVKRGVFHMPH 237
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 72.1 bits (169), Expect = 9e-12
Identities = 68/231 (29%), Positives = 112/231 (48%), Gaps = 22/231 (9%)
Query: 481 FQTDQVLGKGCEGTF---VYRGTFDKRDVAV---KRLLPECFTFADREVALLRESDAHAH 534
++ ++ LGKG G V+ T K + + ++L +RE+A+L+ + H H
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE-HPH 77
Query: 535 VVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593
V++ + +K++ Y+ LE S L DY+ KK K ++ + RQ L HS
Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK-EARKFFRQIISALDFCHSHS 136
Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653
I HRD+KP N+LL + +R I+DFG++ L +G S G+ + PE+I
Sbjct: 137 ICHRDLKPENLLLDEKN---NIR--IADFGMA-SLQVGD---SLLETSCGSPHYACPEVI 187
Query: 654 NGER-TTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDH 701
GE+ D++S G V + L G PF D RQ + G +++ H
Sbjct: 188 RGEKYDGRKADVWSCG-VILFALLVGALPFDDDNLRQLLEKVKRGVFHMPH 237
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.137 0.419
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 142,142,889
Number of Sequences: 224733
Number of extensions: 6219280
Number of successful extensions: 22398
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1460
Number of HSP's successfully gapped in prelim test: 1166
Number of HSP's that attempted gapping in prelim test: 18343
Number of HSP's gapped (non-prelim): 3071
length of query: 973
length of database: 73,234,838
effective HSP length: 97
effective length of query: 876
effective length of database: 51,435,737
effective search space: 45057705612
effective search space used: 45057705612
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 70 (32.3 bits)
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