BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000180-TA|BGIBMGA000180-PA|IPR002372|Pyrrolo-quinoline quinone, IPR000719|Protein kinase, IPR010513|Ribonuclease 2-5A, IPR011009|Protein kinase-like, IPR011047|Quinonprotein alcohol dehydrogenase-like, IPR008271|Serine/threonine protein kinase, active site, IPR002290|Serine/threonine protein kinase, IPR006567|PUG (973 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI000051A3C5 Cluster: PREDICTED: similar to ire-1 CG45... 855 0.0 UniRef50_UPI00015B426F Cluster: PREDICTED: similar to serine thr... 851 0.0 UniRef50_Q16QF5 Cluster: Serine threonine-protein kinase; n=3; C... 761 0.0 UniRef50_Q5TTF0 Cluster: ENSANGP00000029215; n=1; Anopheles gamb... 707 0.0 UniRef50_Q9VDT7 Cluster: CG4583-PA; n=2; Sophophora|Rep: CG4583-... 547 e-154 UniRef50_UPI0000E49D4B Cluster: PREDICTED: similar to protein ki... 479 e-133 UniRef50_O75460 Cluster: Serine/threonine-protein kinase/endorib... 463 e-129 UniRef50_A7RUN1 Cluster: Predicted protein; n=1; Nematostella ve... 460 e-128 UniRef50_Q6GPM2 Cluster: MGC83537 protein; n=4; Tetrapoda|Rep: M... 435 e-120 UniRef50_Q09499 Cluster: Serine/threonine-protein kinase/endorib... 402 e-110 UniRef50_A5YM46 Cluster: ERN2 protein; n=1; Homo sapiens|Rep: ER... 400 e-110 UniRef50_Q76MJ5 Cluster: Serine/threonine-protein kinase/endorib... 398 e-109 UniRef50_O94537 Cluster: Serine/threonine-protein kinase ppk4 pr... 298 4e-79 UniRef50_P32361 Cluster: Serine/threonine-protein kinase/endorib... 276 2e-72 UniRef50_Q6FUI3 Cluster: Similar to sp|P32361 Saccharomyces cere... 276 2e-72 UniRef50_Q4WKP8 Cluster: Protein kinase and ribonuclease Ire1, p... 269 2e-70 UniRef50_A5DU16 Cluster: Putative uncharacterized protein; n=1; ... 269 2e-70 UniRef50_Q4P7S2 Cluster: Putative uncharacterized protein; n=1; ... 267 9e-70 UniRef50_A6SFQ8 Cluster: Serine/threonine-protein kinase; n=1; B... 266 1e-69 UniRef50_Q0UXD0 Cluster: Putative uncharacterized protein; n=1; ... 264 1e-68 UniRef50_A7EHN1 Cluster: Putative uncharacterized protein; n=1; ... 261 7e-68 UniRef50_Q4RJK1 Cluster: Chromosome 3 SCAF15037, whole genome sh... 250 1e-64 UniRef50_Q9FS17 Cluster: OsIre1p; n=4; Oryza sativa|Rep: OsIre1p... 250 1e-64 UniRef50_A7PKV5 Cluster: Chromosome chr7 scaffold_20, whole geno... 231 5e-59 UniRef50_Q01DV0 Cluster: Endoribonuclease/protein kinase IRE1-li... 229 3e-58 UniRef50_UPI000049A534 Cluster: protein kinase; n=1; Entamoeba h... 224 8e-57 UniRef50_UPI0000499C39 Cluster: protein kinase; n=1; Entamoeba h... 223 2e-56 UniRef50_Q55GJ2 Cluster: Putative uncharacterized protein ireA; ... 213 1e-53 UniRef50_Q9FIN6 Cluster: Gb|AAD32909.1; n=5; core eudicotyledons... 202 3e-50 UniRef50_UPI0000E24A3D Cluster: PREDICTED: endoplasmic reticulum... 198 6e-49 UniRef50_A7QPE4 Cluster: Chromosome chr18 scaffold_137, whole ge... 196 2e-48 UniRef50_Q0WPT1 Cluster: Endoribonuclease/protein kinase IRE1; n... 185 6e-45 UniRef50_Q2UR79 Cluster: Serine/threonine protein kinase and end... 184 8e-45 UniRef50_Q5BGU5 Cluster: Putative uncharacterized protein; n=2; ... 180 2e-43 UniRef50_Q759H2 Cluster: ADR293Cp; n=2; Saccharomycetaceae|Rep: ... 166 2e-39 UniRef50_Q557G1 Cluster: Putative uncharacterized protein; n=1; ... 166 3e-39 UniRef50_A7TTK3 Cluster: Putative uncharacterized protein; n=1; ... 165 7e-39 UniRef50_Q7Z8F3 Cluster: Serine/threonine kinase IREI; n=2; Sord... 164 9e-39 UniRef50_A4QZP3 Cluster: Putative uncharacterized protein; n=1; ... 164 9e-39 UniRef50_UPI000023E202 Cluster: hypothetical protein FG05775.1; ... 159 4e-37 UniRef50_Q5KMH4 Cluster: Protein kinase/endoribonuclease, putati... 158 8e-37 UniRef50_Q7S470 Cluster: Putative uncharacterized protein NCU022... 157 1e-36 UniRef50_Q6BJZ1 Cluster: Similar to CA0532|CaIRE1 Candida albica... 157 1e-36 UniRef50_Q23F24 Cluster: Protein kinase domain containing protei... 154 1e-35 UniRef50_Q5A7G9 Cluster: Likely protein kinase/endoribonuclease ... 153 3e-35 UniRef50_A3LWV1 Cluster: Predicted protein; n=2; Pichia|Rep: Pre... 149 4e-34 UniRef50_Q55DJ9 Cluster: Putative uncharacterized protein irlD; ... 148 6e-34 UniRef50_UPI0000F1E427 Cluster: PREDICTED: similar to SPAC167.01... 148 8e-34 UniRef50_Q55DJ8 Cluster: Putative uncharacterized protein irlC; ... 146 2e-33 UniRef50_Q54IE8 Cluster: Putative uncharacterized protein irlE; ... 144 8e-33 UniRef50_Q86IF7 Cluster: Similar to Arabidopsis thaliana (Mouse-... 140 1e-31 UniRef50_Q9SF12 Cluster: Putative uncharacterized protein F26K24... 136 2e-30 UniRef50_UPI0000F21EB0 Cluster: PREDICTED: similar to Endoplasmi... 133 2e-29 UniRef50_Q86AL1 Cluster: Similar to Dictyostelium discoideum (Sl... 130 2e-28 UniRef50_A4RRT4 Cluster: Predicted protein; n=2; Ostreococcus|Re... 108 8e-22 UniRef50_Q4TFM3 Cluster: Chromosome 18 SCAF4374, whole genome sh... 104 1e-20 UniRef50_UPI00006CB13C Cluster: Protein kinase domain containing... 102 5e-20 UniRef50_A0CYE6 Cluster: Chromosome undetermined scaffold_31, wh... 101 9e-20 UniRef50_UPI0000D9D513 Cluster: PREDICTED: similar to Serine/thr... 100 2e-19 UniRef50_A0CAC3 Cluster: Chromosome undetermined scaffold_161, w... 99 3e-19 UniRef50_UPI00006CFA8B Cluster: Protein kinase domain containing... 99 5e-19 UniRef50_A0C060 Cluster: Chromosome undetermined scaffold_14, wh... 98 1e-18 UniRef50_UPI000049869A Cluster: receptor protein kinase; n=4; En... 97 2e-18 UniRef50_Q386V5 Cluster: Protein kinase, putative; n=1; Trypanos... 97 3e-18 UniRef50_Q5KHJ6 Cluster: MAP kinase kinase kinase, putative; n=2... 96 4e-18 UniRef50_A0DUI6 Cluster: Chromosome undetermined scaffold_64, wh... 96 5e-18 UniRef50_A6C731 Cluster: Serine/threonine protein kinase; n=1; P... 95 6e-18 UniRef50_Q9NH60 Cluster: Calcium/calmodulin-dependent protein ki... 95 1e-17 UniRef50_Q9NH59 Cluster: Calcium/calmodulin-dependent protein ki... 95 1e-17 UniRef50_Q9NH58 Cluster: Calcium/calmodulin-dependent protein ki... 95 1e-17 UniRef50_A2GB48 Cluster: CAMK family protein kinase; n=1; Tricho... 95 1e-17 UniRef50_Q7Z8J5 Cluster: MAP kinase kinase kinase; n=1; Yarrowia... 95 1e-17 UniRef50_Q8ER22 Cluster: Serine:threonine protein kinase; n=2; B... 93 3e-17 UniRef50_Q240Z1 Cluster: Protein kinase domain containing protei... 93 3e-17 UniRef50_Q9NYY3 Cluster: Serine/threonine-protein kinase PLK2; n... 93 3e-17 UniRef50_Q2SLI8 Cluster: Serine/threonine protein kinase; n=2; H... 93 3e-17 UniRef50_Q1CYT1 Cluster: Serine/threonine protein kinase; n=2; C... 93 3e-17 UniRef50_Q5XTZ4 Cluster: Salt-inducible protein kinase; n=2; Poa... 93 3e-17 UniRef50_A0C5Z9 Cluster: Chromosome undetermined scaffold_151, w... 93 3e-17 UniRef50_A5DK85 Cluster: Putative uncharacterized protein; n=1; ... 93 3e-17 UniRef50_A2DY61 Cluster: CAMK family protein kinase; n=1; Tricho... 93 4e-17 UniRef50_A0BF29 Cluster: Chromosome undetermined scaffold_103, w... 93 4e-17 UniRef50_Q556S2 Cluster: Putative uncharacterized protein; n=2; ... 92 6e-17 UniRef50_A0CA77 Cluster: Chromosome undetermined scaffold_160, w... 92 6e-17 UniRef50_Q5AHF2 Cluster: Potential pheromone pathway MAPKKK; n=3... 92 6e-17 UniRef50_Q01YI9 Cluster: Serine/threonine protein kinase; n=1; S... 92 8e-17 UniRef50_Q86SG6 Cluster: Serine/threonine-protein kinase Nek8; n... 92 8e-17 UniRef50_Q8SQT4 Cluster: NIMA-LIKE SER/THR PROTEIN KINASE; n=1; ... 91 1e-16 UniRef50_A5DV77 Cluster: Putative uncharacterized protein; n=1; ... 91 1e-16 UniRef50_Q7UEM6 Cluster: Serine/threonine protein kinase; n=1; P... 91 1e-16 UniRef50_A6FXR0 Cluster: Serine/threonine protein kinase; n=1; P... 91 1e-16 UniRef50_A4A0R5 Cluster: Probable serine/threonine-protein kinas... 91 1e-16 UniRef50_Q4RL54 Cluster: Chromosome 12 SCAF15023, whole genome s... 91 2e-16 UniRef50_A0CWQ7 Cluster: Chromosome undetermined scaffold_3, who... 91 2e-16 UniRef50_A0BDG2 Cluster: Chromosome undetermined scaffold_100, w... 91 2e-16 UniRef50_A7M6H7 Cluster: Calcium/calmodulin-dependent protein ki... 91 2e-16 UniRef50_UPI0000ECAA30 Cluster: Serine/threonine-protein kinase/... 90 2e-16 UniRef50_A3ZYY0 Cluster: Serine/threonine protein kinase; n=1; B... 90 2e-16 UniRef50_Q4Q6Y5 Cluster: Protein kinase-like protein; n=3; Leish... 90 3e-16 UniRef50_Q233F7 Cluster: Protein kinase domain containing protei... 90 3e-16 UniRef50_A0C693 Cluster: Chromosome undetermined scaffold_151, w... 90 3e-16 UniRef50_Q9HFR3 Cluster: Mekk; n=1; Pneumocystis carinii|Rep: Me... 90 3e-16 UniRef50_A6CBR9 Cluster: Serine/threonine protein kinase; n=1; P... 89 4e-16 UniRef50_Q4DQP8 Cluster: Protein kinase-like protein, putative; ... 89 4e-16 UniRef50_Q9FKL3 Cluster: Similarity to protein kinase; n=1; Arab... 89 5e-16 UniRef50_Q9VW24 Cluster: CG8789-PA, isoform A; n=3; Diptera|Rep:... 89 5e-16 UniRef50_Q6BFD3 Cluster: Calcium-dependent protein kinase, putat... 89 5e-16 UniRef50_A0BFB3 Cluster: Chromosome undetermined scaffold_103, w... 89 5e-16 UniRef50_UPI000155BF68 Cluster: PREDICTED: hypothetical protein,... 89 7e-16 UniRef50_A6G5N1 Cluster: Serine/threonine protein kinase; n=1; P... 89 7e-16 UniRef50_A5ZMI3 Cluster: Putative uncharacterized protein; n=1; ... 89 7e-16 UniRef50_Q6EE08 Cluster: Fertilization-related kinase 2; n=1; So... 89 7e-16 UniRef50_P53355 Cluster: Death-associated protein kinase 1; n=68... 89 7e-16 UniRef50_UPI0000DB7108 Cluster: PREDICTED: similar to Death-asso... 88 9e-16 UniRef50_UPI00006CF2DC Cluster: Protein kinase domain containing... 88 9e-16 UniRef50_A7QMH3 Cluster: Chromosome chr19 scaffold_126, whole ge... 88 9e-16 UniRef50_Q54L00 Cluster: Zn binding domain-containing protein; n... 88 9e-16 UniRef50_Q229U9 Cluster: Protein kinase domain containing protei... 88 9e-16 UniRef50_A0CKT6 Cluster: Chromosome undetermined scaffold_20, wh... 88 9e-16 UniRef50_A0BQ14 Cluster: Chromosome undetermined scaffold_12, wh... 88 9e-16 UniRef50_UPI00004998B6 Cluster: cell division control protein 7;... 88 1e-15 UniRef50_A6CBF4 Cluster: Serine/threonine protein kinase; n=1; P... 88 1e-15 UniRef50_Q247W3 Cluster: Protein kinase domain containing protei... 88 1e-15 UniRef50_A0BPJ3 Cluster: Chromosome undetermined scaffold_12, wh... 88 1e-15 UniRef50_P53350 Cluster: Serine/threonine-protein kinase PLK1; n... 88 1e-15 UniRef50_P11730 Cluster: Calcium/calmodulin-dependent protein ki... 88 1e-15 UniRef50_Q13555 Cluster: Calcium/calmodulin-dependent protein ki... 88 1e-15 UniRef50_A0C9W0 Cluster: Chromosome undetermined scaffold_16, wh... 87 2e-15 UniRef50_Q6CVC4 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 87 2e-15 UniRef50_Q13554 Cluster: Calcium/calmodulin-dependent protein ki... 87 2e-15 UniRef50_UPI000155511B Cluster: PREDICTED: similar to Calcium/ca... 87 2e-15 UniRef50_UPI00015A4045 Cluster: Serine/threonine-protein kinase ... 87 2e-15 UniRef50_Q7UX63 Cluster: Probable serine/threonine-protein kinas... 87 2e-15 UniRef50_Q5WFL0 Cluster: Serine/threonine protein kinase; n=1; B... 87 2e-15 UniRef50_A7Q6K4 Cluster: Chromosome chr11 scaffold_56, whole gen... 87 2e-15 UniRef50_Q54L02 Cluster: LIM domain-containing protein; n=1; Dic... 87 2e-15 UniRef50_O44997 Cluster: Dap (Death-associated protein) kinase h... 87 2e-15 UniRef50_Q2H8Z5 Cluster: Putative uncharacterized protein; n=2; ... 87 2e-15 UniRef50_Q696W0 Cluster: Striated muscle preferentially expresse... 87 2e-15 UniRef50_Q8IU85 Cluster: Calcium/calmodulin-dependent protein ki... 87 2e-15 UniRef50_UPI00004990CF Cluster: protein kinase; n=1; Entamoeba h... 87 3e-15 UniRef50_Q4RSE0 Cluster: Chromosome 13 SCAF15000, whole genome s... 87 3e-15 UniRef50_Q5Z1J1 Cluster: Putative serine/threonine protein kinas... 87 3e-15 UniRef50_Q1EW82 Cluster: Protein kinase:PASTA:Serine/threonine p... 87 3e-15 UniRef50_Q9LRY7 Cluster: Similarity to protein kinase; n=3; Arab... 87 3e-15 UniRef50_A0C4R4 Cluster: Chromosome undetermined scaffold_15, wh... 87 3e-15 UniRef50_A0LLB3 Cluster: Serine/threonine protein kinase with TP... 86 4e-15 UniRef50_A7RQY7 Cluster: Predicted protein; n=1; Nematostella ve... 86 4e-15 UniRef50_Q20845 Cluster: Serine/threonine-protein kinase plk-3; ... 86 4e-15 UniRef50_UPI000069FC64 Cluster: Serine/threonine-protein kinase ... 86 5e-15 UniRef50_UPI000069FC63 Cluster: Serine/threonine-protein kinase ... 86 5e-15 UniRef50_A6GFX5 Cluster: Serine/threonine protein kinase; n=1; P... 86 5e-15 UniRef50_Q57VI0 Cluster: Polo-like protein kinase; n=3; Trypanos... 86 5e-15 UniRef50_A7AUM8 Cluster: Ser/Thr protein kinase, putative; n=1; ... 86 5e-15 UniRef50_Q6FXI1 Cluster: Candida glabrata strain CBS138 chromoso... 86 5e-15 UniRef50_Q6L2T2 Cluster: Serine/threonine protein kinase; n=1; P... 86 5e-15 UniRef50_O75385 Cluster: Serine/threonine-protein kinase ULK1; n... 86 5e-15 UniRef50_UPI0000D556BE Cluster: PREDICTED: similar to CG7186-PA;... 85 7e-15 UniRef50_A6G2I7 Cluster: Serine/threonine protein kinase; n=1; P... 85 7e-15 UniRef50_A6CD99 Cluster: Probable serine/threonine-protein kinas... 85 7e-15 UniRef50_A3ZWN5 Cluster: Probable serine/threonine-protein kinas... 85 7e-15 UniRef50_Q10NR1 Cluster: Mitogen-activated protein kinase 1, put... 85 7e-15 UniRef50_Q23FR5 Cluster: Protein kinase domain containing protei... 85 7e-15 UniRef50_A7SP26 Cluster: Predicted protein; n=1; Nematostella ve... 85 7e-15 UniRef50_A2F620 Cluster: STE family protein kinase; n=1; Trichom... 85 7e-15 UniRef50_A0E1K1 Cluster: Chromosome undetermined scaffold_73, wh... 85 7e-15 UniRef50_Q0USU3 Cluster: Putative uncharacterized protein; n=1; ... 85 7e-15 UniRef50_A7TJU8 Cluster: Putative uncharacterized protein; n=1; ... 85 7e-15 UniRef50_UPI0000498BDB Cluster: cell division control protein 7;... 85 9e-15 UniRef50_UPI000023D1D8 Cluster: hypothetical protein FG05484.1; ... 85 9e-15 UniRef50_Q6PHV6 Cluster: Serine/threonine kinase 17b; n=1; Danio... 85 9e-15 UniRef50_Q47SX3 Cluster: Tyrosine protein kinase:Serine/threonin... 85 9e-15 UniRef50_A6G500 Cluster: Serine/threonine protein kinase; n=1; P... 85 9e-15 UniRef50_A0E202 Cluster: Chromosome undetermined scaffold_74, wh... 85 9e-15 UniRef50_A0DM08 Cluster: Chromosome undetermined scaffold_56, wh... 85 9e-15 UniRef50_A0D824 Cluster: Chromosome undetermined scaffold_40, wh... 85 9e-15 UniRef50_O42625 Cluster: MAPKK kinase; n=6; Pezizomycotina|Rep: ... 85 9e-15 UniRef50_Q9H4B4 Cluster: Serine/threonine-protein kinase PLK3; n... 85 9e-15 UniRef50_P54740 Cluster: Serine/threonine-protein kinase pkaB; n... 85 9e-15 UniRef50_UPI0000DB7B8A Cluster: PREDICTED: similar to CG8789-PA,... 85 1e-14 UniRef50_Q7UVF2 Cluster: Serine/threonine protein kinase; n=1; P... 85 1e-14 UniRef50_Q3ACF7 Cluster: Putative serine/threonine protein kinas... 85 1e-14 UniRef50_Q3DW89 Cluster: Protein kinase:PASTA:Serine/threonine p... 85 1e-14 UniRef50_A4SBG1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 85 1e-14 UniRef50_Q22AD4 Cluster: Protein kinase domain containing protei... 85 1e-14 UniRef50_A2FTS4 Cluster: CAMK family protein kinase; n=2; Tricho... 85 1e-14 UniRef50_A2EJ98 Cluster: AGC family protein kinase; n=2; Trichom... 85 1e-14 UniRef50_A0EHY9 Cluster: Chromosome undetermined scaffold_98, wh... 85 1e-14 UniRef50_A0CDW7 Cluster: Chromosome undetermined scaffold_17, wh... 85 1e-14 UniRef50_A0CA86 Cluster: Chromosome undetermined scaffold_160, w... 85 1e-14 UniRef50_Q4PCB9 Cluster: Putative uncharacterized protein; n=1; ... 85 1e-14 UniRef50_Q9CEF5 Cluster: Probable serine/threonine-protein kinas... 85 1e-14 UniRef50_Q39008 Cluster: Mitogen-activated protein kinase kinase... 85 1e-14 UniRef50_UPI0000499655 Cluster: protein kinase; n=2; Entamoeba h... 84 2e-14 UniRef50_A2RRW8 Cluster: LOC100037118 protein; n=1; Xenopus laev... 84 2e-14 UniRef50_A7IE03 Cluster: Protein kinase; n=1; Xanthobacter autot... 84 2e-14 UniRef50_A6CG99 Cluster: Serine/threonine protein kinase; n=1; P... 84 2e-14 UniRef50_Q9SA26 Cluster: F3O9.7 protein; n=3; Arabidopsis thalia... 84 2e-14 UniRef50_Q86HN7 Cluster: Similar to Asterina pectinifera (Starfi... 84 2e-14 UniRef50_Q22W86 Cluster: Protein kinase domain containing protei... 84 2e-14 UniRef50_A0CDN2 Cluster: Chromosome undetermined scaffold_17, wh... 84 2e-14 UniRef50_Q9HFT9 Cluster: Ste11alpha protein; n=5; Tremellomycete... 84 2e-14 UniRef50_A1CZC9 Cluster: MAP kinase kinase kinase Ste11/SteC; n=... 84 2e-14 UniRef50_P23561 Cluster: Serine/threonine-protein kinase STE11; ... 84 2e-14 UniRef50_P34331 Cluster: Serine/threonine-protein kinase plk-1; ... 84 2e-14 UniRef50_P28829 Cluster: Protein kinase byr2; n=3; Schizosacchar... 84 2e-14 UniRef50_UPI00015B4881 Cluster: PREDICTED: similar to serine/thr... 84 2e-14 UniRef50_Q6BFH8 Cluster: Protein kinase, putative; n=3; Parameci... 84 2e-14 UniRef50_Q5DBY2 Cluster: SJCHGC06342 protein; n=1; Schistosoma j... 84 2e-14 UniRef50_A0E054 Cluster: Chromosome undetermined scaffold_71, wh... 84 2e-14 UniRef50_A0D467 Cluster: Chromosome undetermined scaffold_37, wh... 84 2e-14 UniRef50_O15865 Cluster: Calcium-dependent protein kinase 2; n=2... 84 2e-14 UniRef50_UPI00015B60DA Cluster: PREDICTED: similar to calcium/ca... 83 3e-14 UniRef50_UPI0000E7FBCB Cluster: PREDICTED: similar to NIMA (neve... 83 3e-14 UniRef50_UPI00006CF367 Cluster: Protein kinase domain containing... 83 3e-14 UniRef50_Q2S2K2 Cluster: Protein kinase domain; n=1; Salinibacte... 83 3e-14 UniRef50_Q4UF19 Cluster: Serine/threonine protein kinase, putati... 83 3e-14 UniRef50_A5K3W6 Cluster: Serine/threonine protein kinase, putati... 83 3e-14 UniRef50_A0DFE9 Cluster: Chromosome undetermined scaffold_49, wh... 83 3e-14 UniRef50_A0CJV4 Cluster: Chromosome undetermined scaffold_2, who... 83 3e-14 UniRef50_UPI0000F20581 Cluster: PREDICTED: similar to Endoplasmi... 83 4e-14 UniRef50_Q182R7 Cluster: Serine/threonine-protein kinase and pho... 83 4e-14 UniRef50_A2UAS7 Cluster: Serine/threonine protein kinase; n=2; B... 83 4e-14 UniRef50_Q75I98 Cluster: Putative uncharacterized protein OSJNBa... 83 4e-14 UniRef50_A7PH70 Cluster: Chromosome chr17 scaffold_16, whole gen... 83 4e-14 UniRef50_Q4QEC3 Cluster: Protein kinase, putative; n=4; Leishman... 83 4e-14 UniRef50_A3FQ16 Cluster: Calmodulin-domain protein kinase 1, put... 83 4e-14 UniRef50_A0DMG4 Cluster: Chromosome undetermined scaffold_56, wh... 83 4e-14 UniRef50_A0CWJ1 Cluster: Chromosome undetermined scaffold_3, who... 83 4e-14 UniRef50_A0CS09 Cluster: Chromosome undetermined scaffold_26, wh... 83 4e-14 UniRef50_A0CRU6 Cluster: Chromosome undetermined scaffold_25, wh... 83 4e-14 UniRef50_O59790 Cluster: Serine/threonine-protein kinase ark1; n... 83 4e-14 UniRef50_UPI0000D9C1EE Cluster: PREDICTED: similar to calcium/ca... 83 5e-14 UniRef50_Q4RVD3 Cluster: Chromosome 15 SCAF14992, whole genome s... 83 5e-14 UniRef50_Q6MBC4 Cluster: Putative serine/threonine protein kinas... 83 5e-14 UniRef50_A0W4X5 Cluster: Serine/threonine protein kinase with Ch... 83 5e-14 UniRef50_Q9BMX6 Cluster: Phosphoinositide-dependent protein kina... 83 5e-14 UniRef50_Q8IL26 Cluster: Ser/Thr protein kinase, putative; n=1; ... 83 5e-14 UniRef50_Q4Q920 Cluster: Protein kinase, putative; n=3; Leishman... 83 5e-14 UniRef50_A0DFL9 Cluster: Chromosome undetermined scaffold_49, wh... 83 5e-14 UniRef50_Q756N1 Cluster: AER223Cp; n=1; Eremothecium gossypii|Re... 83 5e-14 UniRef50_A4RDS9 Cluster: Putative uncharacterized protein; n=1; ... 83 5e-14 UniRef50_A3LT13 Cluster: Predicted protein; n=1; Pichia stipitis... 83 5e-14 UniRef50_A4IFZ4 Cluster: LOC565828 protein; n=2; Euteleostomi|Re... 82 6e-14 UniRef50_Q895P6 Cluster: Serine/threonine protein kinase; n=6; C... 82 6e-14 UniRef50_Q4JYC1 Cluster: Serine/threonine protein kinase PknB; n... 82 6e-14 UniRef50_P74451 Cluster: Serine/threonine protein kinase; n=1; S... 82 6e-14 UniRef50_A6CDL3 Cluster: Probable protein kinase yloP-putative s... 82 6e-14 UniRef50_A3DCY1 Cluster: Serine/threonine protein kinase; n=1; C... 82 6e-14 UniRef50_Q5EC56 Cluster: Phosphoenolpyruvate carboxylase kinase ... 82 6e-14 UniRef50_A4S2A1 Cluster: Predicted protein; n=1; Ostreococcus lu... 82 6e-14 UniRef50_Q7QVC9 Cluster: GLP_542_34639_36963; n=1; Giardia lambl... 82 6e-14 UniRef50_Q55EC7 Cluster: RasGEF domain-containing protein; n=1; ... 82 6e-14 UniRef50_O01700 Cluster: Putative uncharacterized protein dlk-1;... 82 6e-14 UniRef50_A2E6I9 Cluster: AGC family protein kinase; n=2; Trichom... 82 6e-14 UniRef50_A0C8K1 Cluster: Chromosome undetermined scaffold_158, w... 82 6e-14 UniRef50_Q8SSH1 Cluster: SPK1-LIKE SER/THR PROTEIN KINASE; n=1; ... 82 6e-14 UniRef50_A5DYF0 Cluster: Calcium/calmodulin-dependent protein ki... 82 6e-14 UniRef50_UPI00006CB362 Cluster: Protein kinase domain containing... 82 8e-14 UniRef50_UPI0000ECD6BF Cluster: Serine/threonine-protein kinase ... 82 8e-14 UniRef50_Q81ZV3 Cluster: Putative serine/threonine protein kinas... 82 8e-14 UniRef50_A4J588 Cluster: Protein kinase; n=2; Peptococcaceae|Rep... 82 8e-14 UniRef50_Q67W58 Cluster: Putative ethylene-inducible CTR1-like p... 82 8e-14 UniRef50_Q4CXJ5 Cluster: Protein kinase, putative; n=3; Trypanos... 82 8e-14 UniRef50_Q22S16 Cluster: Protein kinase domain containing protei... 82 8e-14 UniRef50_Q6FWK3 Cluster: Similar to sp|P27636 Saccharomyces cere... 82 8e-14 UniRef50_A7F066 Cluster: Putative uncharacterized protein; n=1; ... 82 8e-14 UniRef50_Q8FUI4 Cluster: Serine/threonine-protein kinases drp72;... 82 8e-14 UniRef50_UPI00015B6237 Cluster: PREDICTED: similar to Mos; n=1; ... 81 1e-13 UniRef50_UPI00015B580D Cluster: PREDICTED: similar to serine/thr... 81 1e-13 UniRef50_UPI000150A956 Cluster: Protein kinase domain containing... 81 1e-13 UniRef50_UPI00006CFB83 Cluster: Protein kinase domain containing... 81 1e-13 UniRef50_UPI000049A290 Cluster: protein kinase; n=1; Entamoeba h... 81 1e-13 UniRef50_Q56A46 Cluster: Zgc:113355; n=3; Clupeocephala|Rep: Zgc... 81 1e-13 UniRef50_Q9K9Z0 Cluster: Serine/threonine protein kinase; n=1; B... 81 1e-13 UniRef50_Q4JYC0 Cluster: Serine/threonine protein kinase PknA; n... 81 1e-13 UniRef50_Q08QR7 Cluster: Serine/threonine protein kinase; n=2; C... 81 1e-13 UniRef50_A7H748 Cluster: Protein kinase; n=2; Anaeromyxobacter|R... 81 1e-13 UniRef50_A6GIW6 Cluster: Serine/threonine kinase PKN8; n=2; Ples... 81 1e-13 UniRef50_A6GH84 Cluster: Serine/threonine protein kinase; n=1; P... 81 1e-13 UniRef50_A3ZQZ2 Cluster: Serine/threonine protein kinase; n=1; B... 81 1e-13 UniRef50_A3ZQ01 Cluster: Serine/threonine protein kinase; n=1; B... 81 1e-13 UniRef50_A1UQJ4 Cluster: Protein kinase; n=2; Mycobacterium|Rep:... 81 1e-13 UniRef50_Q9LN78 Cluster: T12C24.22; n=9; Magnoliophyta|Rep: T12C... 81 1e-13 UniRef50_Q9VCL7 Cluster: CG10177-PA; n=2; Drosophila melanogaste... 81 1e-13 UniRef50_Q16QY2 Cluster: Ribosomal protein S6 kinase, 90kD, poly... 81 1e-13 UniRef50_A7AMU3 Cluster: Protein kinase domain containing protei... 81 1e-13 UniRef50_A2G6P7 Cluster: CAMK family protein kinase; n=1; Tricho... 81 1e-13 UniRef50_A0DYT2 Cluster: Chromosome undetermined scaffold_7, who... 81 1e-13 UniRef50_A0DX23 Cluster: Chromosome undetermined scaffold_68, wh... 81 1e-13 UniRef50_Q5Y251 Cluster: STE11p; n=3; Tremellomycetes|Rep: STE11... 81 1e-13 UniRef50_Q9GT24 Cluster: Probable serine/threonine-protein kinas... 81 1e-13 UniRef50_Q8TDC3 Cluster: BR serine/threonine-protein kinase 1; n... 81 1e-13 UniRef50_UPI0000F2C92F Cluster: PREDICTED: similar to serine/thr... 81 1e-13 UniRef50_UPI0000DB7791 Cluster: PREDICTED: similar to NIMA (neve... 81 1e-13 UniRef50_UPI0000DA331E Cluster: PREDICTED: similar to serine/thr... 81 1e-13 UniRef50_UPI00004988DF Cluster: protein kinase; n=1; Entamoeba h... 81 1e-13 UniRef50_UPI000023D792 Cluster: hypothetical protein FG06326.1; ... 81 1e-13 UniRef50_UPI000065E88B Cluster: Serine/threonine-protein kinase ... 81 1e-13 UniRef50_Q7UM74 Cluster: Probable serine/threonine-protein kinas... 81 1e-13 UniRef50_Q7UFH1 Cluster: Probable serine/threonine-specific prot... 81 1e-13 UniRef50_Q3AC24 Cluster: Putative serine/threonine protein kinas... 81 1e-13 UniRef50_A1SCN7 Cluster: Protein kinase; n=1; Nocardioides sp. J... 81 1e-13 UniRef50_Q9SAJ2 Cluster: T8K14.1 protein; n=3; Arabidopsis thali... 81 1e-13 UniRef50_A7QS17 Cluster: Chromosome undetermined scaffold_155, w... 81 1e-13 UniRef50_A5AQH5 Cluster: Putative uncharacterized protein; n=1; ... 81 1e-13 UniRef50_Q86NL8 Cluster: RE70136p; n=3; Sophophora|Rep: RE70136p... 81 1e-13 UniRef50_Q761X1 Cluster: Putative uncharacterized protein; n=1; ... 81 1e-13 UniRef50_Q5CTY5 Cluster: Calcium/calmodulin dependent protein ki... 81 1e-13 UniRef50_Q23WW0 Cluster: Protein kinase domain containing protei... 81 1e-13 UniRef50_Q22UA7 Cluster: Protein kinase domain containing protei... 81 1e-13 UniRef50_A3FQM1 Cluster: Putative uncharacterized protein; n=2; ... 81 1e-13 UniRef50_A0EG18 Cluster: Chromosome undetermined scaffold_94, wh... 81 1e-13 UniRef50_Q8X1F0 Cluster: PAK1 kinase; n=3; Filobasidiella neofor... 81 1e-13 UniRef50_Q4P2M4 Cluster: Putative uncharacterized protein; n=1; ... 81 1e-13 UniRef50_A6SDS8 Cluster: Putative uncharacterized protein; n=1; ... 81 1e-13 UniRef50_O14965 Cluster: Serine/threonine-protein kinase 6; n=40... 81 1e-13 UniRef50_P15735 Cluster: Phosphorylase b kinase gamma catalytic ... 81 1e-13 UniRef50_UPI000049857F Cluster: protein kinase; n=1; Entamoeba h... 81 2e-13 UniRef50_Q4SK53 Cluster: Chromosome 2 SCAF14570, whole genome sh... 81 2e-13 UniRef50_Q5EUE4 Cluster: Cyclin-dependent kinase-activating kina... 81 2e-13 UniRef50_Q0PIH7 Cluster: Ser/Thr protein kinase; n=1; Heliobacil... 81 2e-13 UniRef50_A6G1T7 Cluster: Serine/threonine protein kinase; n=1; P... 81 2e-13 UniRef50_A6C7D1 Cluster: Tyrosine protein kinase:Serine/threonin... 81 2e-13 UniRef50_Q8IGS1 Cluster: RE38276p; n=2; Drosophila melanogaster|... 81 2e-13 UniRef50_Q23KJ6 Cluster: Protein kinase domain containing protei... 81 2e-13 UniRef50_A4VDW8 Cluster: Calcium-dependent protein kinase; n=1; ... 81 2e-13 UniRef50_A0EHT5 Cluster: Chromosome undetermined scaffold_98, wh... 81 2e-13 UniRef50_A0D0B4 Cluster: Chromosome undetermined scaffold_33, wh... 81 2e-13 UniRef50_A0CL90 Cluster: Chromosome undetermined scaffold_20, wh... 81 2e-13 UniRef50_A0C214 Cluster: Chromosome undetermined scaffold_143, w... 81 2e-13 UniRef50_Q8TGH8 Cluster: Bck1-like MAP kinase kinase kinase; n=1... 81 2e-13 UniRef50_Q7S4G0 Cluster: Putative uncharacterized protein NCU022... 81 2e-13 UniRef50_A6C4A6 Cluster: Probable serine/threonine-protein kinas... 80 3e-13 UniRef50_A3ZN78 Cluster: Serine/threonine protein kinase; n=1; B... 80 3e-13 UniRef50_Q9STG4 Cluster: Putative uncharacterized protein T6H20.... 80 3e-13 UniRef50_A3BQK4 Cluster: Putative uncharacterized protein; n=2; ... 80 3e-13 UniRef50_Q93107 Cluster: Myosin I heavy chain kinase; n=1; Acant... 80 3e-13 UniRef50_Q5KSL4 Cluster: Mos; n=1; Apis mellifera|Rep: Mos - Api... 80 3e-13 UniRef50_Q5CHJ7 Cluster: Calcium-dependent protein kinase; n=4; ... 80 3e-13 UniRef50_Q551J3 Cluster: Putative uncharacterized protein; n=2; ... 80 3e-13 UniRef50_Q54WS5 Cluster: Pleckstrin homology (PH) domain-contain... 80 3e-13 UniRef50_Q22BG7 Cluster: Protein kinase domain containing protei... 80 3e-13 UniRef50_A2E535 Cluster: CAMK family protein kinase; n=1; Tricho... 80 3e-13 UniRef50_A0E864 Cluster: Chromosome undetermined scaffold_82, wh... 80 3e-13 UniRef50_A0DZW9 Cluster: Chromosome undetermined scaffold_70, wh... 80 3e-13 UniRef50_A0DDN1 Cluster: Chromosome undetermined scaffold_47, wh... 80 3e-13 UniRef50_A0CZ76 Cluster: Chromosome undetermined scaffold_32, wh... 80 3e-13 UniRef50_A0CEP3 Cluster: Chromosome undetermined scaffold_172, w... 80 3e-13 UniRef50_Q55U80 Cluster: Putative uncharacterized protein; n=3; ... 80 3e-13 UniRef50_UPI00015B5A6C Cluster: PREDICTED: hypothetical protein;... 80 3e-13 UniRef50_UPI00004986C0 Cluster: protein kinase; n=1; Entamoeba h... 80 3e-13 UniRef50_Q4S5N1 Cluster: Chromosome 9 SCAF14729, whole genome sh... 80 3e-13 UniRef50_Q7URD9 Cluster: Serine/threonine protein kinase; n=1; P... 80 3e-13 UniRef50_A6G4V4 Cluster: Serine/threonine protein kinase; n=1; P... 80 3e-13 UniRef50_Q554C0 Cluster: LISK family protein kinase; n=2; Dictyo... 80 3e-13 UniRef50_Q54R82 Cluster: Protein serine/threonine kinase; n=2; D... 80 3e-13 UniRef50_Q22XZ7 Cluster: Protein kinase domain containing protei... 80 3e-13 UniRef50_A2E7E2 Cluster: CAMK family protein kinase; n=1; Tricho... 80 3e-13 UniRef50_A0DG90 Cluster: Chromosome undetermined scaffold_5, who... 80 3e-13 UniRef50_A0DBV2 Cluster: Chromosome undetermined scaffold_45, wh... 80 3e-13 UniRef50_Q64702 Cluster: Serine/threonine-protein kinase PLK4; n... 80 3e-13 UniRef50_P65733 Cluster: Probable serine/threonine-protein kinas... 80 3e-13 UniRef50_O54784 Cluster: Death-associated protein kinase 3; n=16... 80 3e-13 UniRef50_UPI000049A0D5 Cluster: protein kinase; n=1; Entamoeba h... 79 4e-13 UniRef50_UPI0000499714 Cluster: protein kinase; n=3; Entamoeba h... 79 4e-13 UniRef50_UPI0000498D8F Cluster: protein kinase; n=2; Entamoeba h... 79 4e-13 UniRef50_UPI0000660B42 Cluster: Homolog of Homo sapiens "Serine/... 79 4e-13 UniRef50_Q0AXM0 Cluster: Serine/threonine protein kinase; n=1; S... 79 4e-13 UniRef50_A6CF08 Cluster: Serine/threonine protein kinase; n=1; P... 79 4e-13 UniRef50_Q0DE32 Cluster: Os06g0181200 protein; n=5; Oryza sativa... 79 4e-13 UniRef50_A7P2E2 Cluster: Chromosome chr1 scaffold_5, whole genom... 79 4e-13 UniRef50_A7NXT1 Cluster: Chromosome chr5 scaffold_2, whole genom... 79 4e-13 UniRef50_Q6BG36 Cluster: SNF1-related protein kinase, putative; ... 79 4e-13 UniRef50_Q4DPN9 Cluster: Protein kinase, putative; n=3; Trypanos... 79 4e-13 UniRef50_Q23R88 Cluster: Protein kinase domain containing protei... 79 4e-13 UniRef50_Q22W87 Cluster: Protein kinase domain containing protei... 79 4e-13 UniRef50_A0DGK3 Cluster: Chromosome undetermined scaffold_5, who... 79 4e-13 UniRef50_A0BW59 Cluster: Chromosome undetermined scaffold_131, w... 79 4e-13 UniRef50_A5E6H6 Cluster: Putative uncharacterized protein; n=1; ... 79 4e-13 UniRef50_O94768 Cluster: Serine/threonine-protein kinase 17B; n=... 79 4e-13 UniRef50_O00444 Cluster: Serine/threonine-protein kinase PLK4; n... 79 4e-13 UniRef50_O42565 Cluster: LIM domain kinase 1; n=4; Coelomata|Rep... 79 4e-13 UniRef50_UPI00015B628A Cluster: PREDICTED: similar to LD14856p; ... 79 6e-13 UniRef50_UPI0000F1E715 Cluster: PREDICTED: similar to serine/thr... 79 6e-13 UniRef50_UPI000023D36F Cluster: hypothetical protein FG08701.1; ... 79 6e-13 UniRef50_Q4S965 Cluster: Chromosome 3 SCAF14700, whole genome sh... 79 6e-13 UniRef50_Q97PA9 Cluster: Serine/threonine protein kinase; n=15; ... 79 6e-13 UniRef50_Q47XY2 Cluster: Protein kinase domain protein; n=1; Col... 79 6e-13 UniRef50_Q2RK10 Cluster: Serine/threonine protein kinase; n=1; M... 79 6e-13 UniRef50_Q5EUE6 Cluster: Putative serine/threonine protein kinas... 79 6e-13 UniRef50_Q1FLS9 Cluster: Putative uncharacterized protein; n=1; ... 79 6e-13 UniRef50_Q01YB1 Cluster: Serine/threonine protein kinase; n=1; S... 79 6e-13 UniRef50_A6NUT2 Cluster: Putative uncharacterized protein; n=1; ... 79 6e-13 UniRef50_A5Z9Q8 Cluster: Putative uncharacterized protein; n=1; ... 79 6e-13 UniRef50_A5G0B5 Cluster: Protein kinase; n=1; Acidiphilium crypt... 79 6e-13 UniRef50_A4X0Y3 Cluster: Protein kinase; n=3; Actinomycetales|Re... 79 6e-13 UniRef50_A4F5S3 Cluster: Serine/threonine protein kinase; n=5; A... 79 6e-13 UniRef50_A1GF65 Cluster: Serine/threonine protein kinase; n=2; S... 79 6e-13 UniRef50_A7PYX6 Cluster: Chromosome chr12 scaffold_38, whole gen... 79 6e-13 UniRef50_Q4QEZ0 Cluster: Protein kinase, putative; n=3; Leishman... 79 6e-13 UniRef50_Q4D1J3 Cluster: Protein kinase, putative; n=2; Trypanos... 79 6e-13 UniRef50_Q240Z4 Cluster: Protein kinase domain containing protei... 79 6e-13 UniRef50_Q16RU6 Cluster: Mitogen-activated protein kinase kinase... 79 6e-13 UniRef50_A4I2U0 Cluster: Protein kinase, putative; n=3; Leishman... 79 6e-13 UniRef50_A2FF57 Cluster: CAMK family protein kinase; n=1; Tricho... 79 6e-13 UniRef50_A0DI56 Cluster: Chromosome undetermined scaffold_51, wh... 79 6e-13 UniRef50_A0DHI3 Cluster: Chromosome undetermined scaffold_50, wh... 79 6e-13 UniRef50_A0BVP1 Cluster: Chromosome undetermined scaffold_130, w... 79 6e-13 UniRef50_A2QHV0 Cluster: Contig An04c0070, complete genome; n=4;... 79 6e-13 UniRef50_Q6P3R8 Cluster: Serine/threonine-protein kinase Nek5; n... 79 6e-13 UniRef50_P11801 Cluster: Serine/threonine-protein kinase H1; n=3... 79 6e-13 UniRef50_P38692 Cluster: Serine/threonine-protein kinase KIC1; n... 79 6e-13 UniRef50_Q7RAH3 Cluster: Calcium-dependent protein kinase 1; n=2... 79 6e-13 UniRef50_P27636 Cluster: Cell division control protein 15; n=3; ... 79 6e-13 UniRef50_UPI00006CFF91 Cluster: Protein kinase domain containing... 79 8e-13 UniRef50_UPI00006CDA40 Cluster: Protein kinase domain containing... 79 8e-13 UniRef50_A5ZAP7 Cluster: Putative uncharacterized protein; n=1; ... 79 8e-13 UniRef50_Q9LQA1 Cluster: F4N2.17; n=8; Magnoliophyta|Rep: F4N2.1... 79 8e-13 UniRef50_Q9LDQ1 Cluster: T12C24.12; n=4; core eudicotyledons|Rep... 79 8e-13 UniRef50_Q7XTK4 Cluster: Putative mitogen-activated protein kina... 79 8e-13 UniRef50_A7P1R5 Cluster: Chromosome chr19 scaffold_4, whole geno... 79 8e-13 UniRef50_Q7RJE3 Cluster: Mus musculus GCN2alpha; n=9; Plasmodium... 79 8e-13 UniRef50_A7RR18 Cluster: Predicted protein; n=2; Nematostella ve... 79 8e-13 UniRef50_A2E1S0 Cluster: AGC family protein kinase; n=1; Trichom... 79 8e-13 UniRef50_A0E889 Cluster: Chromosome undetermined scaffold_82, wh... 79 8e-13 UniRef50_A0CDT3 Cluster: Chromosome undetermined scaffold_17, wh... 79 8e-13 UniRef50_A0C2Z2 Cluster: Chromosome undetermined scaffold_145, w... 79 8e-13 UniRef50_O74297 Cluster: CPC3 protein; n=2; Sordariomycetes|Rep:... 79 8e-13 UniRef50_A6R8E8 Cluster: Putative uncharacterized protein; n=1; ... 79 8e-13 UniRef50_Q6C3D7 Cluster: Serine/threonine-protein kinase STE20; ... 79 8e-13 UniRef50_Q9UEE5 Cluster: Serine/threonine-protein kinase 17A; n=... 79 8e-13 UniRef50_Q05655 Cluster: Protein kinase C delta type; n=61; Eume... 79 8e-13 UniRef50_UPI0000519D29 Cluster: PREDICTED: similar to maternal e... 78 1e-12 UniRef50_Q47KC3 Cluster: Tyrosine protein kinase:Serine/threonin... 78 1e-12 UniRef50_Q3VHV4 Cluster: Protein kinase; n=2; Pelodictyon phaeoc... 78 1e-12 UniRef50_A6FYY8 Cluster: Serine/threonine protein kinase; n=1; P... 78 1e-12 UniRef50_Q9M1Z9 Cluster: Receptor lectin kinase-like protein; n=... 78 1e-12 UniRef50_Q24DS8 Cluster: Protein kinase domain containing protei... 78 1e-12 UniRef50_Q08666 Cluster: Protein serine/threonine kinase; n=2; E... 78 1e-12 UniRef50_A2GAV1 Cluster: CAMK family protein kinase; n=1; Tricho... 78 1e-12 UniRef50_A2F807 Cluster: CAMK family protein kinase; n=1; Tricho... 78 1e-12 UniRef50_A2EB11 Cluster: CAMK family protein kinase; n=3; Tricho... 78 1e-12 UniRef50_A0EEC5 Cluster: Chromosome undetermined scaffold_91, wh... 78 1e-12 UniRef50_A0E675 Cluster: Chromosome undetermined scaffold_8, who... 78 1e-12 UniRef50_A0E012 Cluster: Chromosome undetermined scaffold_71, wh... 78 1e-12 UniRef50_A0C1C8 Cluster: Chromosome undetermined scaffold_141, w... 78 1e-12 UniRef50_Q5B3J3 Cluster: Putative uncharacterized protein; n=1; ... 78 1e-12 UniRef50_Q10056 Cluster: Serine/threonine-protein kinase shk2; n... 78 1e-12 UniRef50_Q9BZL6 Cluster: Serine/threonine-protein kinase D2; n=1... 78 1e-12 UniRef50_UPI00006CCFDA Cluster: Protein kinase domain containing... 78 1e-12 UniRef50_Q3SI75 Cluster: Serine/Threonine protein kinase; n=1; T... 78 1e-12 UniRef50_A6GJA8 Cluster: Serine/threonine protein kinase; n=1; P... 78 1e-12 UniRef50_Q96285 Cluster: Receptor-like kinase; n=8; Arabidopsis ... 78 1e-12 UniRef50_A4S6E4 Cluster: Predicted protein; n=2; Ostreococcus|Re... 78 1e-12 UniRef50_Q8IKX5 Cluster: Protein kinase, putative; n=7; Plasmodi... 78 1e-12 UniRef50_A2EE93 Cluster: AGC family protein kinase; n=1; Trichom... 78 1e-12 UniRef50_A0E7F6 Cluster: Chromosome undetermined scaffold_81, wh... 78 1e-12 UniRef50_A0E6L8 Cluster: Chromosome undetermined scaffold_8, who... 78 1e-12 UniRef50_A0DLP7 Cluster: Chromosome undetermined scaffold_556, w... 78 1e-12 UniRef50_A0D3X3 Cluster: Chromosome undetermined scaffold_37, wh... 78 1e-12 UniRef50_A0CTT3 Cluster: Chromosome undetermined scaffold_27, wh... 78 1e-12 UniRef50_A0CJM5 Cluster: Chromosome undetermined scaffold_2, who... 78 1e-12 UniRef50_A0CDK7 Cluster: Chromosome undetermined scaffold_17, wh... 78 1e-12 UniRef50_A0C2X8 Cluster: Chromosome undetermined scaffold_145, w... 78 1e-12 UniRef50_A0BQC5 Cluster: Chromosome undetermined scaffold_120, w... 78 1e-12 UniRef50_A6R025 Cluster: Predicted protein; n=1; Ajellomyces cap... 78 1e-12 UniRef50_Q9Y6E0 Cluster: Serine/threonine-protein kinase 24; n=1... 78 1e-12 UniRef50_Q7RZD3 Cluster: Serine/threonine-protein kinase ste-20;... 78 1e-12 UniRef50_P52304 Cluster: Serine/threonine-protein kinase polo; n... 78 1e-12 UniRef50_P0A5S5 Cluster: Probable serine/threonine-protein kinas... 78 1e-12 UniRef50_UPI00015551F0 Cluster: PREDICTED: similar to Serine/thr... 77 2e-12 UniRef50_UPI0000D57103 Cluster: PREDICTED: similar to CG32666-PB... 77 2e-12 UniRef50_UPI000049A581 Cluster: protein kinase; n=1; Entamoeba h... 77 2e-12 UniRef50_UPI0000498E32 Cluster: protein kinase; n=2; Entamoeba h... 77 2e-12 UniRef50_Q4RX00 Cluster: Chromosome 11 SCAF14979, whole genome s... 77 2e-12 UniRef50_Q2J4L0 Cluster: Serine/threonine protein kinase; n=3; F... 77 2e-12 UniRef50_Q9KX10 Cluster: Protein kinase; n=17; Staphylococcus|Re... 77 2e-12 UniRef50_Q5EUI6 Cluster: Putative serine/threonine protein kinas... 77 2e-12 UniRef50_A6FWP3 Cluster: Serine/threonine kinase family protein;... 77 2e-12 UniRef50_A6C6H6 Cluster: Serine/threonine protein kinase; n=1; P... 77 2e-12 UniRef50_Q8MVX2 Cluster: Putative serine/threonine protein kinas... 77 2e-12 UniRef50_Q584V3 Cluster: Protein kinase, putative; n=1; Trypanos... 77 2e-12 UniRef50_Q55CZ1 Cluster: Putative transmembrane protein; n=1; Di... 77 2e-12 UniRef50_Q4R2X5 Cluster: Mos; n=1; Athalia rosae|Rep: Mos - Atha... 77 2e-12 UniRef50_Q38FL3 Cluster: Protein kinase, putative; n=3; Trypanos... 77 2e-12 UniRef50_A2EJW2 Cluster: CAMK family protein kinase; n=1; Tricho... 77 2e-12 UniRef50_A2DAR5 Cluster: AGC family protein kinase; n=1; Trichom... 77 2e-12 UniRef50_A0DGC5 Cluster: Chromosome undetermined scaffold_5, who... 77 2e-12 UniRef50_A0CX34 Cluster: Chromosome undetermined scaffold_3, who... 77 2e-12 UniRef50_A0CV67 Cluster: Chromosome undetermined scaffold_29, wh... 77 2e-12 UniRef50_A0CEY3 Cluster: Chromosome undetermined scaffold_173, w... 77 2e-12 UniRef50_A0BN05 Cluster: Chromosome undetermined scaffold_117, w... 77 2e-12 UniRef50_A0BJ86 Cluster: Chromosome undetermined scaffold_11, wh... 77 2e-12 UniRef50_A0BET2 Cluster: Chromosome undetermined scaffold_102, w... 77 2e-12 UniRef50_Q59EH6 Cluster: 3-phosphoinositide dependent protein ki... 77 2e-12 UniRef50_A5DCL7 Cluster: Putative uncharacterized protein; n=1; ... 77 2e-12 UniRef50_Q13188 Cluster: Serine/threonine-protein kinase 3; n=84... 77 2e-12 UniRef50_Q8R9T6 Cluster: Probable serine/threonine-protein kinas... 77 2e-12 UniRef50_O15530 Cluster: 3-phosphoinositide-dependent protein ki... 77 2e-12 >UniRef50_UPI000051A3C5 Cluster: PREDICTED: similar to ire-1 CG4583-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to ire-1 CG4583-PA - Apis mellifera Length = 968 Score = 855 bits (2115), Expect = 0.0 Identities = 439/861 (50%), Positives = 566/861 (65%), Gaps = 37/861 (4%) Query: 19 QPVVKVPSQ-DANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDG 77 +P+VKVP + MP FLPDP+ G LY +G + + LKKLPFTIP+LVAN+PCRS+DG Sbjct: 82 EPIVKVPVELGRTSMPMFLPDPKDGSLYVFGT--ETEALKKLPFTIPQLVANSPCRSSDG 139 Query: 78 ILYTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILM 137 ILYTG+K DTWF IDP TG RE + GFDK K NTC E + +++ RTEY+I+M Sbjct: 140 ILYTGRKIDTWFGIDPRTGQREQLLGFDKVK-------NTCPVEMQNAVFMGRTEYSIIM 192 Query: 138 HDSKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFG 197 DSK N KWNVTF+DY++ M + + +Y +HF ++S GR+++ DRK G ++W + Sbjct: 193 VDSKQKNRKWNVTFYDYSATKMEPEGIENYDLVHFATSSTGRIVTVDRKLGIILWELDVQ 252 Query: 198 TPVVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLKNSNIELYPTLYVGEHN 257 +PV+A Y++ DGL++VPF S+ D+TL+ I+ K +N K S+I+L+PTLY+G+H Sbjct: 253 SPVIAVYIVREDGLLTVPFTSVADETLNLIL---KRFAN----KPSDIQLFPTLYIGQHR 305 Query: 258 HGLYALSSLVDKNTITISTGHQPLLIEGPSTETLKTNAPRYEPIKNIHYKLSDLNLHVSA 317 HGLYAL SLVD T TIS LL+EGP + P+ N + LSD + Sbjct: 306 HGLYALPSLVDLTTATISNNIGQLLLEGP------LSVPQLGKNDNGNVPLSDTYNNEYQ 359 Query: 318 PYLLLGHYKVPELTTSWIPHLPNSNVLNLRDPQIDSIKLINGAVQAQTENDVENETNLKS 377 + LGHY++P + + DP I+++ L Q+ ++++ KS Sbjct: 360 AVITLGHYEIP--AEYKLQESQPLQITGRSDPVIETLPLRYSNSTKQSLFSLQDDE--KS 415 Query: 378 NSVSVSVQTEDLFEGLSFRPDLWYKQAHVWLHQQENKVLKVALIILVGLVIAMFWYLRLQ 437 N+ + + + + + Y W QQENK LK+ LI+L+G ++ MFWYL Q Sbjct: 416 NNDTNNESWREFMQNV-------YTMGKNWFSQQENKGLKLTLIVLLGCILVMFWYLNAQ 468 Query: 438 AREFXXXXXXXXXXXXXXXXXXXXXXXXLM--EIGEGEMKIGKITFQTDQVLGKGCEGTF 495 +EF ++ ++GEG +K+GKITF T QVLGKGCEGTF Sbjct: 469 FKEFQQLSQGSRENNSTSDYYGTRSNALVVPEDMGEGVVKVGKITFDTGQVLGKGCEGTF 528 Query: 496 VYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELC 555 VYRG FD R VAVKRLLP+CFTFADREVALLRESDAHA+VVRY+CTE+D+ FRYIALEL Sbjct: 529 VYRGNFDGRSVAVKRLLPDCFTFADREVALLRESDAHANVVRYFCTEQDRMFRYIALELA 588 Query: 556 SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEV 615 ATLQDYV K + + KI + ILRQAT GL+HLH +DIVHRD+KPHNVLLS P GEV Sbjct: 589 EATLQDYVAGKYDKK-KISAKSILRQATSGLAHLHLLDIVHRDIKPHNVLLSTPGPRGEV 647 Query: 616 RAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVL 675 RAMISDFGL KKL +GRVSFSRRSGVTGTDGWIAPEM+NG RTT ++DIFSLGCVFYYVL Sbjct: 648 RAMISDFGLCKKLQLGRVSFSRRSGVTGTDGWIAPEMLNGNRTTCAVDIFSLGCVFYYVL 707 Query: 676 SKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETI 735 S G+HPFGD LRRQANIL G+ +L L + + + + ILI+AMI+ PS RPP + Sbjct: 708 SNGKHPFGDPLRRQANILCGENDLTALHDEISQNDKELALILIKAMIANNPSERPPVMAV 767 Query: 736 LKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLERGGARVLRGDWRVRVCRVVAGDL 795 +P+FW IL F QDVSD+VE A LE RV++GDWR+ + VA DL Sbjct: 768 HDHPIFWEPAKILGFFQDVSDRVEKEETSSPALLALEFECNRVVQGDWRLLIDVEVATDL 827 Query: 796 RTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVWL 855 R R+YRG+ V LLRA+RNKKHHYREL ++SLG +PD F YWL+RFP LL HVW Sbjct: 828 RKYRSYRGESVRDLLRALRNKKHHYRELSQQAQESLGYIPDKFTEYWLSRFPSLLSHVWC 887 Query: 856 QMQQYRDEDILQTYYPRTYVF 876 MQ +R+E L+ YY Y F Sbjct: 888 AMQTFRNEPTLRDYYHADYTF 908 >UniRef50_UPI00015B426F Cluster: PREDICTED: similar to serine threonine-protein kinase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to serine threonine-protein kinase - Nasonia vitripennis Length = 973 Score = 851 bits (2105), Expect = 0.0 Identities = 434/884 (49%), Positives = 573/884 (64%), Gaps = 45/884 (5%) Query: 19 QPVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGI 78 +P VKVP D N MP FLPDP+ G LY +GP + + LKKLPFTIP+LVA++PCRS+DGI Sbjct: 64 EPAVKVP-HDTNQMPVFLPDPKDGSLYLFGP--ETEALKKLPFTIPQLVASSPCRSSDGI 120 Query: 79 LYTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMH 138 LYTG+K DTWF +DP TG RE + GF K+ +NTC + + IYV RTEYNI+M Sbjct: 121 LYTGRKIDTWFSVDPKTGEREQLLGFSKA-------DNTCPIDTQNAIYVGRTEYNIIMI 173 Query: 139 DSKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGT 198 DSK + KWNVTF+DY++ M +++ DY HF +S G+V++ DR G+ +W+ N G+ Sbjct: 174 DSKRKDRKWNVTFYDYSAAKMDNELVEDYDLAHFAGSSTGQVVTLDR-FGNTLWNINLGS 232 Query: 199 PVVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLKNSNIELYPTLYVGEHNH 258 PV+A Y + +DGLI++PF S+ + TL +++ + + + +PTLY+GEH+H Sbjct: 233 PVIAIYTISKDGLITIPFTSVSESTLGQLLQKI-------AINPNEFQFFPTLYIGEHSH 285 Query: 259 GLYALSSLVDKNTITISTGHQPLLIEGPSTETLKTNAPRYEPIKNIHYKLSDLNLH-VSA 317 GLYAL S D T TI++ LL+EGP ++ N P + + + + A Sbjct: 286 GLYALPSFSDSATPTIASKAGQLLLEGPIISQMQKNESPPPPFDGGSKEPLESDFQRIGA 345 Query: 318 P---YLLLGHYKVPELTTSWIPHLPNSNVLNLRDPQIDSIKLINGAVQAQTENDVENETN 374 ++LGHY+VP + + PH + DP I T+ + N+T Sbjct: 346 DKNNIMILGHYEVP---SEYKPHNQPLQITGRSDPVI------------LTKGNTFNKTK 390 Query: 375 LKSNSVSVSVQTEDLFEGLSFRPDLW--YKQAHVWLHQQENKVLKVALIILVGLVIAMFW 432 +++ + ++ +R L Y + WL+QQENK LK+ALIILVG V+ MFW Sbjct: 391 KIDLTINEKQLNDSGYDSRGWRRALSISYAASKKWLNQQENKGLKLALIILVGCVVTMFW 450 Query: 433 YLRLQAREFXXXXXXXXXXXXXXXXXXXXXXXXLM----EIGEGEMKIGKITFQTDQVLG 488 YL Q +EF + EIGEG +++GKITF ++VLG Sbjct: 451 YLNAQFKEFQQLSQQFDQGSRENSRTGSNGRNGTIYTPEEIGEGLVRVGKITFNAEEVLG 510 Query: 489 KGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFR 548 KGC+GTFVY+G FD R VAVKRLLP+CFTFADREVALLRESDAHA+VVRY+CTE+D+ FR Sbjct: 511 KGCDGTFVYKGEFDGRSVAVKRLLPDCFTFADREVALLRESDAHANVVRYFCTEQDRLFR 570 Query: 549 YIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSM 608 YIALEL ATLQDYV + + KI + IL+QAT GL+HLHS+DIVHRD+KPHNVLLS+ Sbjct: 571 YIALELAEATLQDYVAGRYD-RTKISTKNILKQATSGLAHLHSLDIVHRDIKPHNVLLSV 629 Query: 609 PSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLG 668 P GEVRAMISDFGL KKL GR+SFSRRSGVTGTDGWIAPEM+NG+RTT ++D+FSLG Sbjct: 630 PGPRGEVRAMISDFGLCKKLQRGRMSFSRRSGVTGTDGWIAPEMLNGQRTTYAVDVFSLG 689 Query: 669 CVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSA 728 CVFYYVLS G+HPFGD LRRQANIL G+ +L L I ++ V + +LI+AM+ + P Sbjct: 690 CVFYYVLSSGKHPFGDPLRRQANILCGEIDLTALQNISENDKQVAL-VLIKAMVDSDPLK 748 Query: 729 RPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLERGGARVLRGDWRVRVC 788 RPP + I +PMFW +L F QDVSD+VE A LERG +V++GDWR+ + Sbjct: 749 RPPAQAIHDHPMFWDAAQVLTFFQDVSDRVEKDGSESPALRALERGNRKVVQGDWRLHID 808 Query: 789 RVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPL 848 VA DLR R+YRG+ V LLRA+RNKKHHYREL + + SLG++P F YWL+RFP Sbjct: 809 VEVATDLRKYRSYRGESVRDLLRALRNKKHHYRELTVEAQQSLGEIPTKFTDYWLSRFPH 868 Query: 849 LLPHVWLQMQQYRDEDILQTYYPRTYVFNRDDVIELNNDKDCDY 892 LL H W MQ +R E L++YY Y F +D + + D D+ Sbjct: 869 LLIHSWCAMQNFRSEPTLRSYYDPVYEFKTEDTNDTDVVDDEDF 912 >UniRef50_Q16QF5 Cluster: Serine threonine-protein kinase; n=3; Coelomata|Rep: Serine threonine-protein kinase - Aedes aegypti (Yellowfever mosquito) Length = 1215 Score = 761 bits (1882), Expect = 0.0 Identities = 400/889 (44%), Positives = 555/889 (62%), Gaps = 41/889 (4%) Query: 19 QPVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGI 78 +P ++VPS + + +LPDPR G LYTY R + LKKLP+TIP+LVANAPCRS+DGI Sbjct: 211 EPAIQVPSL-SGMNTHYLPDPRDGSLYTY--RNPEGGLKKLPYTIPQLVANAPCRSSDGI 267 Query: 79 LYTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMH 138 LY+GKKSD WF+IDP TG RE V GF + + + +Y+ RT+Y ++M+ Sbjct: 268 LYSGKKSDDWFLIDPKTGRREKVLGFGTP--LDREKAESIGWATSRSVYLGRTQYTVMMY 325 Query: 139 DS--KNVNHK-WNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHN 195 DS + N K WNVTFFDYTS M ++ +Y +H TS+S+G ++ +RK G +W + Sbjct: 326 DSMSSDQNSKPWNVTFFDYTSHTMAPELTKEYEFLHLTSSSSGMTVTIERKKGTSLWQKD 385 Query: 196 FGTPVVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLKNSNIELYPTLYVGE 255 +PVVA +LL +GL+SVPF ++ DD L I E+ +N+ L+P+LYVGE Sbjct: 386 LSSPVVAVFLLGSEGLLSVPFQTVSDDALRDIKEEGHI---------NNVNLFPSLYVGE 436 Query: 256 HNHGLYALSSLVDKNTITISTGHQPLLIEGPSTETLKTNAP-RYEPIKNIHYKLSDLNLH 314 + +YA+ S+VDK+T T+ + + L+ GP +T+ P R++ I ++ + N+ Sbjct: 437 LTNTIYAIPSMVDKHTATLPSEPRVNLLGGPKRS--ETDDPSRHDLIATDTVQMQNDNI- 493 Query: 315 VSAPYLLLGHYKVPELTTSWIPHLPNSNVLNL-RDPQIDSIKL-INGAVQAQ----TEND 368 ++LGHY+ P+ S H+ + + + +D Q+ ++ L +G +A+ T Sbjct: 494 -----IILGHYQPPKTDESLKLHISSGSAGRMFKDGQLSTVLLGYSGLPKAEDSVKTIGV 548 Query: 369 VENETNLKSNSVSVSVQTEDLFEGLSFRPDLWYKQAHVWLHQQENKVLKVALIILVGLVI 428 ++ + + S+ E F+ L R Y WL Q NK+ + + L G+V+ Sbjct: 549 QTDDDQIPRRNASIYAN-ETSFKALMGR---MYLDVKFWLEAQPNKLPTMMFVALFGVVV 604 Query: 429 AMFWYLRLQAREFXXXXXXXXXXXXXXXXXXXXXXXXLMEIGEGEMKIGKITFQTDQVLG 488 FWY LQ R ++ G+GE+++GKI F T VLG Sbjct: 605 FGFWYFHLQMRALQEQSQNGSQTNSNRSSGGNYAET--IDFGDGEIRVGKINFNTQDVLG 662 Query: 489 KGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFR 548 KGCEGTFV++GTF+KR+VAVKR+LP CFT ADREVALLRESDAH +VVRY+CTE+D+QFR Sbjct: 663 KGCEGTFVFKGTFEKREVAVKRILPGCFTLADREVALLRESDAHENVVRYFCTEQDRQFR 722 Query: 549 YIALELCSATLQDYVEKKLN--FECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLL 606 YIA+ELC+ATLQ+YV+ K F+ +I +E+L+QAT GL HLHS++IVHRD+KP N+LL Sbjct: 723 YIAVELCAATLQEYVDPKSGEAFQKQISVLEVLQQATNGLMHLHSLNIVHRDIKPQNILL 782 Query: 607 SMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFS 666 S+P VRAMISDFGL KKLN G+ SFSRRSGVTGTDGWIAPEM G RTTTS+DIFS Sbjct: 783 SLPDNKKRVRAMISDFGLCKKLNYGKASFSRRSGVTGTDGWIAPEMQRGHRTTTSVDIFS 842 Query: 667 LGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKI-LPEEELVVIKILIRAMISAK 725 LGCVF+YV+SKG HPFGD L+RQANIL+G+Y+L L KI +P+ V+ LI MI+A Sbjct: 843 LGCVFHYVISKGYHPFGDNLKRQANILSGEYDLSALYKIGVPKNLSVLADELICDMIAAD 902 Query: 726 PSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLERGGARVLRGDWRV 785 + RPP + +P+FW + IL+FLQDVSD+VE LER V+R DW + Sbjct: 903 QNKRPPASAVRNHPLFWSNERILSFLQDVSDRVEKSDVLTDPLRTLERNARYVVRDDWSL 962 Query: 786 RVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTR 845 + + + DLR R Y+G V LLRA+RNKKHHY EL DV+++LG +P F YW+ R Sbjct: 963 HLDQEITNDLRKYRGYQGYSVRDLLRALRNKKHHYHELTPDVQEALGAIPHKFTQYWINR 1022 Query: 846 FPLLLPHVWLQMQQYRDEDILQTYYPRTYVFNRDDVIELNNDKDCDYEV 894 FP LL H + + Y E I +YY + N + + +YE+ Sbjct: 1023 FPHLLSHAYHSLADYSHEPIFHSYYNDEVNYQFSKPAYFNEEGNENYEL 1071 >UniRef50_Q5TTF0 Cluster: ENSANGP00000029215; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000029215 - Anopheles gambiae str. PEST Length = 893 Score = 707 bits (1748), Expect = 0.0 Identities = 387/887 (43%), Positives = 534/887 (60%), Gaps = 49/887 (5%) Query: 15 STLSQPVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRS 74 S +P ++VP+ ++ +LPDPR G LY G + LKKLP+TIP+LVA+APCRS Sbjct: 24 SIADEPAIRVPAP-SDTSAHYLPDPRDGSLYRMN--GLEGGLKKLPYTIPQLVASAPCRS 80 Query: 75 TDGILYTGKKSDTWFMIDPLTGFREHVSGFD----KSKIFKSDDENTCNSEKKKGIYVAR 130 +DGILY+GKKSD WF+IDP TG RE V GF ++ +D ++ + +Y+ R Sbjct: 81 SDGILYSGKKSDVWFLIDPKTGQREKVLGFGGAPPQAASKDADGTDSIGWATSRAVYLGR 140 Query: 131 TEYNILMHDS--KNVNHK-WNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKT 187 T+Y ++M+DS + N K WNVTFFDY++ +M ++ +Y +H TS+S+G +F++ Sbjct: 141 TQYTVMMYDSLATDRNSKPWNVTFFDYSAHSMAPELTKEYEFLHLTSSSSGLTATFEQNK 200 Query: 188 GDLVWSHNFGTPVVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLKNSNIEL 247 G +W + +PVVA +LL +GL+SVPF ++ D+ L I E A++ N +K L Sbjct: 201 GTPMWQKDLSSPVVAVFLLGSEGLLSVPFQTVSDEVLQEINERAES-GNFDDMK-----L 254 Query: 248 YPTLYVGEHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTETLKTNAPRYEPIKN--IH 305 + T+Y+GE + LYA+ SLVDKNT T+ + L+ GP LK P P + + Sbjct: 255 FETVYIGEAGNNLYAIPSLVDKNTATLPSEPSINLLGGP----LKRR-PASSPSSSAALT 309 Query: 306 YKLSDLNLHVSAPYLLLGHYKVPELTTSW----IPHLPNSNVLNLRDPQIDSIKLINGAV 361 +L N ++ ++LGHY+ P+ S P P S L S L+ Sbjct: 310 SRLGGKNENI----IILGHYQTPKTDDSIKLDIAPSGPASMGKGLWKHHELSTMLLKTPK 365 Query: 362 QAQT----------ENDVENETNLKSNSVSVSVQTEDLFEGLSFRPDLWYKQAHVWLHQQ 411 + Q+ ++D E+E + + S++ + + + Y +WL Q Sbjct: 366 RPQSTIGVPTDDDDDDDGEHELEYGETNETNSMKLQGSTDFIRALFSRLYMDTKLWLDAQ 425 Query: 412 ENKVLKVALIILVGLVIAMFWYLRLQAREFX------XXXXXXXXXXXXXXXXXXXXXXX 465 NK+ + LI L GLV+ F+Y+ LQ + Sbjct: 426 PNKLPTILLITLFGLVVFGFYYINLQMKALKEQSQQGSQTSNSNRSSGGSGGSGSGSYSE 485 Query: 466 LMEIGEGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVAL 525 M+ G+GEM++GKI F T VLGKGCEGTFV+RG F+KR+VAVKR+LP CFT ADREV L Sbjct: 486 PMDFGDGEMRVGKINFNTQNVLGKGCEGTFVFRGMFEKREVAVKRILPGCFTLADREVTL 545 Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMG 585 LRESDAH +VVRY+CTE+D+QFRYIA+ELC+ATLQDYV+ K KI +++ILRQAT G Sbjct: 546 LRESDAHENVVRYFCTEQDRQFRYIAVELCAATLQDYVDGKGTSTVKISALDILRQATSG 605 Query: 586 LSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTD 645 L HLHS+ IVHRD+KP N+LLS+P VRAMISDFGL KKLN G+ SFSRRSGVTGTD Sbjct: 606 LMHLHSLSIVHRDIKPQNILLSLPDNRQRVRAMISDFGLCKKLNYGKASFSRRSGVTGTD 665 Query: 646 GWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHL--D 703 GWIAPEM G+R TTS+DIFSLGCVFYYVLS G HPFGD L+RQANIL+ +++L L + Sbjct: 666 GWIAPEMQRGQRATTSVDIFSLGCVFYYVLSDGFHPFGDNLKRQANILSDEFDLGMLRRE 725 Query: 704 KILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCAC 763 P+ ++ + L+ MI ++P RP + + ++P+FW IL FLQDVSD+VE Sbjct: 726 NSQPDCRTILAEELVTDMIRSEPGKRPSAKAVSRHPLFWNNGRILAFLQDVSDRVEKLEV 785 Query: 764 GFGAEHPLERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYREL 823 LE+ V+R DW + + DLR R Y+G V LLRA+RNKKHHY EL Sbjct: 786 MTEPLRSLEKNARFVVREDWSRYLDAEITADLRKFRGYQGYSVRDLLRALRNKKHHYHEL 845 Query: 824 ESDVRDSLGKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYY 870 ++ +LG +P F YW++RFP LL H + + E I + YY Sbjct: 846 TPSMQSALGTIPHQFTQYWISRFPRLLSHSYHALADCSREPIFRPYY 892 >UniRef50_Q9VDT7 Cluster: CG4583-PA; n=2; Sophophora|Rep: CG4583-PA - Drosophila melanogaster (Fruit fly) Length = 1038 Score = 547 bits (1350), Expect = e-154 Identities = 306/676 (45%), Positives = 420/676 (62%), Gaps = 64/676 (9%) Query: 18 SQPVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDG 77 S P + Q+ +P FLPDPR G +Y G G LKKLP+TIP+LVANAPCRS+DG Sbjct: 16 SYPPIVAEHQENVQVPHFLPDPRDGSIYQLGQMGS---LKKLPYTIPQLVANAPCRSSDG 72 Query: 78 ILYTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILM 137 ILY+GKKSDTW+M+DP TG RE V GF + + + E + IY+ RT+Y ++M Sbjct: 73 ILYSGKKSDTWYMVDPKTGRREKVMGFGDATVDGKEGEQI-GWATSRAIYLGRTQYTVMM 131 Query: 138 HDS--KNVNHK-WNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSH 194 +DS KN + K WN+TF+DY +++ ++ +Y IH T+T+NG++++ DRK G +W Sbjct: 132 YDSLAKNKDAKPWNITFYDYNAVSAPPELAKEYEYIHLTTTTNGQIVTLDRKHGKFLWQR 191 Query: 195 NFGTPVVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLKNSNIELYPTLYVG 254 + +PVVAA+LL DGL+SVPF ++ D+ I+E++KT G N+ ++L+ +LYVG Sbjct: 192 DLSSPVVAAFLLGPDGLLSVPFTTVSDEAYQAILEESKT-----GNVNT-VKLFQSLYVG 245 Query: 255 EHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTETLKTNAPRYEPIKNIHYKLSDLNLH 314 EH GLYAL SLVDKNT IST L++GP+ + N+ + + I+ L H Sbjct: 246 EHQKGLYALPSLVDKNTPRISTAPPIKLLDGPTGDQ---NSNQETDPRTIYIN-DVLQEH 301 Query: 315 VSAPYLLLGHYKVPELTTSWIPHLPNSNVLNLR-DPQIDSIKLINGAVQAQTENDVENE- 372 ++LGHY ++PN NL+ P S K++ ND Sbjct: 302 AG---IMLGHY-----------NMPNEGNGNLQLSPTTASSKVVQSLATIHNYNDGYGLL 347 Query: 373 TNLKSNSVSVSVQTE-DLFE-GLSFRPD-----------LWYK---QAHV--W-LHQQEN 413 N + N+ + VQT+ +L E G+ R + L QA + W + Sbjct: 348 ANNEKNAADIGVQTDPELVEIGIDQRTNGNTINRTKTIILQNSNKVQAFINEWFMEHPSG 407 Query: 414 KVLKVALIILVGLVIAMFWYLRLQAREF---------XXXXXXXXXXXXXXXXXXXXXXX 464 KV ++ ++I++G+ IA+FWY RE Sbjct: 408 KVHQILIVIVLGM-IALFWYTCSTMRELQKQSENGSKTFAIAQNGSNGSTGSNGSNANAE 466 Query: 465 XLMEIGEGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVA 524 L+++G G++++GKI+F T++VLGKGCEGTFV++GTF++R VAVKRLLPECFTFADREVA Sbjct: 467 DLVDLGNGQVRVGKISFSTNEVLGKGCEGTFVFKGTFEERFVAVKRLLPECFTFADREVA 526 Query: 525 LLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVE--KKLNFECKIDSVEILRQA 582 LLRESDAH +VVRY+CTE+D+QFRYIA+ELC+ATLQDY E + L + ID ++L QA Sbjct: 527 LLRESDAHENVVRYFCTEQDRQFRYIAVELCAATLQDYTEGDRSLELQNHIDVWQVLSQA 586 Query: 583 TMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVT 642 GLSHLHS+DIVHRD+KP NVL+S+P G+VR MISDFGL KKLN G+ SFSRRSGVT Sbjct: 587 ASGLSHLHSLDIVHRDIKPQNVLISLPDAKGKVRVMISDFGLCKKLNFGKTSFSRRSGVT 646 Query: 643 GTDGWIAPEMINGERT 658 GTDGWIAPEM+ +RT Sbjct: 647 GTDGWIAPEMMRSQRT 662 Score = 194 bits (474), Expect = 7e-48 Identities = 98/222 (44%), Positives = 132/222 (59%), Gaps = 2/222 (0%) Query: 659 TTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHL--DKILPEEELVVIKI 716 TT++DIFSLGCV+YYVLS G H FGD L+RQANIL+ +YNL L + + +++ + Sbjct: 692 TTAVDIFSLGCVYYYVLSGGHHAFGDNLKRQANILSHEYNLAKLRPEDDSEDSRIILAEQ 751 Query: 717 LIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLERGGA 776 LI MI P +RPP I +P+FW + +L+FLQDVSD+VE LE+ G Sbjct: 752 LISDMIHKDPQSRPPARCIGNHPLFWDEPKMLSFLQDVSDRVEKLQFHAEPLKSLEKNGR 811 Query: 777 RVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPD 836 V+ DW V + ++ DLR R Y G V LLRA+RNKKHHY EL + LG +P Sbjct: 812 IVVLDDWNVHLDPMITDDLRKYRGYMGASVRDLLRALRNKKHHYHELTPAAQKMLGCIPH 871 Query: 837 GFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYYPRTYVFNR 878 F +YW+ RFP L+ H + +E I + YY Y+F R Sbjct: 872 EFTNYWVDRFPQLISHAYHAFSICSNEPIFKPYYSAGYLFTR 913 >UniRef50_UPI0000E49D4B Cluster: PREDICTED: similar to protein kinase/endoribonulcease; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to protein kinase/endoribonulcease - Strongylocentrotus purpuratus Length = 1112 Score = 479 bits (1182), Expect = e-133 Identities = 231/403 (57%), Positives = 293/403 (72%), Gaps = 4/403 (0%) Query: 469 IGEGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRE 528 + EG +K+GKI F QVLG+GCEGTFV++G FD RD+AVKR+LPECF+FADREV LLRE Sbjct: 578 VPEGFVKVGKILFNPKQVLGQGCEGTFVFKGRFDNRDIAVKRILPECFSFADREVDLLRE 637 Query: 529 SDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSH 588 SD H +V+RY+CTE D QFR+IALELC+ATLQ++V + F + ++IL Q++ GL+H Sbjct: 638 SDEHPNVIRYFCTESDLQFRFIALELCTATLQEFVHDRGRFH-MLKPLDILFQSSSGLAH 696 Query: 589 LHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWI 648 LHS++IVHRD+KPHNVL+S P+ G+V+AMISDFGL KKL+ GR+SFSRRSGV GTDGWI Sbjct: 697 LHSLNIVHRDIKPHNVLISQPNQHGKVKAMISDFGLCKKLSAGRMSFSRRSGVAGTDGWI 756 Query: 649 APEMING-ERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILP 707 APEM+ G +RTTT+IDIFSLGCVFYYVLS G+HPFGD L RQANI++G+Y+LD L Sbjct: 757 APEMLTGQDRTTTAIDIFSLGCVFYYVLSNGKHPFGDSLHRQANIISGEYSLDLLPPDKR 816 Query: 708 EEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGA 767 +E + LI M+ RP IL++P FW + L F QDVSD++E Sbjct: 817 NDE--IAHQLITQMVDPYFDTRPEANAILRHPFFWYPEKQLAFFQDVSDRIEKEPLDCPL 874 Query: 768 EHPLERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDV 827 LE G V+RGDWR + + DLR R YRG V LLRA+RNKKHH+REL +V Sbjct: 875 LVALETGAQNVVRGDWRNNITEELQTDLRKFRAYRGHSVRDLLRAMRNKKHHFRELPEEV 934 Query: 828 RDSLGKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYY 870 + SLGK+PD FV Y+ +RFPLLL HV+ + R+E +L YY Sbjct: 935 KASLGKVPDQFVKYFTSRFPLLLLHVYDALSLCREEPVLSKYY 977 Score = 192 bits (469), Expect = 3e-47 Identities = 117/325 (36%), Positives = 181/325 (55%), Gaps = 20/325 (6%) Query: 20 PVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGIL 79 PVVK+ + + FLPDP G LY GP GD LKKLP TIP +V+++P R D +L Sbjct: 82 PVVKMAVDNPDGFT-FLPDPTDGTLYVLGPGGDG--LKKLPLTIPSIVSSSPFRGPDNML 138 Query: 80 YTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHD 139 YTG+K+DTW +D SG K + +++C +++ RTE+ + M D Sbjct: 139 YTGRKADTWIAVDV-------NSGHKKQTLTTESSQSSCPLTSSSTLFLGRTEFTVTMFD 191 Query: 140 SKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTP 199 S N N WNVTF DY+S + D N Y HF+S ++G++++ D+KTG+++W + +P Sbjct: 192 STNSNKIWNVTFADYSS-HVSSDQSN-YDLRHFSSIADGQMVTLDKKTGEMLWVTSHSSP 249 Query: 200 VVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAK--TLSNGKGLKNSNIELYPTLYVGEHN 257 VVA Y L +GL V ++ +TL H+++ + T N + +L PTLY+G++ Sbjct: 250 VVAMYRLLGEGLHKVAHTAVSPNTLGHLLDGGEYPTWRNQLLGYTKHTKLVPTLYIGDYP 309 Query: 258 HGLYALSSLVDKNTI-TISTGHQPLLIEGPSTETLKTNAPRYEPIKNIHYKLSDLNLHVS 316 GL AL +LV++ T+ IS G P L+EGP + + R +P N LSD ++ Sbjct: 310 SGLLALPALVEEETVPIISRGWSPPLLEGPGFDGITPPNDRDKPPMN---PLSD-GTNIQ 365 Query: 317 APYLLLGHYKVPELTTSWIPHLPNS 341 +LLG++++P + P P S Sbjct: 366 G-LILLGYHELPANSIMIRPTAPVS 389 Score = 45.2 bits (102), Expect = 0.009 Identities = 18/30 (60%), Positives = 24/30 (80%) Query: 469 IGEGEMKIGKITFQTDQVLGKGCEGTFVYR 498 + EG +K+GKI F QVLG+GCEGTFV++ Sbjct: 501 VPEGFVKVGKILFNPKQVLGQGCEGTFVFK 530 >UniRef50_O75460 Cluster: Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Inositol-requiring protein 1) (hIRE1p) (IRE1a) (Ire1-alpha) (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]; n=22; Euteleostomi|Rep: Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Inositol-requiring protein 1) (hIRE1p) (IRE1a) (Ire1-alpha) (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] - Homo sapiens (Human) Length = 977 Score = 463 bits (1142), Expect = e-129 Identities = 224/399 (56%), Positives = 288/399 (72%), Gaps = 7/399 (1%) Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535 +GKI+F VLG G EGT VYRG FD RDVAVKR+LPECF+FADREV LLRESD H +V Sbjct: 566 VGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNV 625 Query: 536 VRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIV 595 +RY+CTE+D+QF+YIA+ELC+ATLQ+YVE+K ++ + +L+Q T GL+HLHS++IV Sbjct: 626 IRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIV 685 Query: 596 HRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN- 654 HRD+KPHN+L+SMP+ G+++AMISDFGL KKL +GR SFSRRSGV GT+GWIAPEM++ Sbjct: 686 HRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSE 745 Query: 655 --GERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEE-EL 711 E T ++DIFS GCVFYYV+S+G HPFG L+RQANIL G +LD L PE+ E Sbjct: 746 DCKENPTYTVDIFSAGCVFYYVVSEGSHPFGKSLQRQANILLGACSLDCLH---PEKHED 802 Query: 712 VVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPL 771 V+ + LI MI+ P RP +LK+P FW + L F QDVSD++E + L Sbjct: 803 VIARELIEKMIAMDPQKRPSANDVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQL 862 Query: 772 ERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSL 831 ERGG V++ DWR + + DLR RTY+G V LLRA+RNKKHHYREL ++VR++L Sbjct: 863 ERGGRAVVKMDWRENITDPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETL 922 Query: 832 GKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYY 870 G LPD FV Y+ +RFP LL H + M+ E + Q YY Sbjct: 923 GTLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYY 961 Score = 187 bits (456), Expect = 1e-45 Identities = 119/338 (35%), Positives = 186/338 (55%), Gaps = 31/338 (9%) Query: 20 PVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGIL 79 PV++VP+ P FLPDP G LYT G + ++ L KLPFTIPELV +PCRS+DGIL Sbjct: 60 PVLQVPTHVEE--PAFLPDPNDGSLYTLGSKNNEG-LTKLPFTIPELVQASPCRSSDGIL 116 Query: 80 YTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHD 139 Y GKK D W++ID LTG ++ S F ++ C S +Y+ RTEY I M+D Sbjct: 117 YMGKKQDIWYVIDLLTGEKQQT----LSSAFA---DSLCPSTSL--LYLGRTEYTITMYD 167 Query: 140 SKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTP 199 +K +WN T+FDY + ++ +D DY HF S +G V++ D ++GD++W N+ +P Sbjct: 168 TKTRELRWNATYFDYAA-SLPEDE-GDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASP 225 Query: 200 VVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLK-------NSNIELYPTLY 252 VVA Y+ R+GL V ++ +TL ++ + + K + +L PTLY Sbjct: 226 VVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLY 285 Query: 253 VGEHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTETLKTNAPRYE----PIKNIHY-- 306 VG+++ LYA S+V + + G L+EGP T+ + T + E P ++ + Sbjct: 286 VGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGV-TIGDKGECVITPSTDVKFDP 344 Query: 307 --KLSDLNLHVSAPYLLLGHYKVP-ELTTSWIPHLPNS 341 K + ++ +LL+GH++ P +T + PN+ Sbjct: 345 GLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNN 382 >UniRef50_A7RUN1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 924 Score = 460 bits (1135), Expect = e-128 Identities = 224/401 (55%), Positives = 284/401 (70%), Gaps = 7/401 (1%) Query: 474 MKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHA 533 + +GKITF V+G+GCEGT VY+G FD RDVAVKR+LPECF+FADREVALLRESDAHA Sbjct: 526 ISVGKITFCLKDVIGRGCEGTVVYKGKFDGRDVAVKRILPECFSFADREVALLRESDAHA 585 Query: 534 HVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 +VVRY+C E+D QFRYIALELC TLQ+YVE ++ + +L+QAT GL+HLHS++ Sbjct: 586 NVVRYFCMEQDHQFRYIALELCDVTLQEYVEDPRFDRSELQPLTVLQQATSGLAHLHSLN 645 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 IVHRD+KPHNVL+S + +G V MISDFGL KKL GR S + RSG GTDGWIAPEM Sbjct: 646 IVHRDIKPHNVLISKAT-SGHVNVMISDFGLCKKLTYGRSSVTCRSGAAGTDGWIAPEMF 704 Query: 654 -NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEEL- 711 R S+DIFS GC+FYYVLS G HPFGD RRQANI++G+ NLD LP+ E Sbjct: 705 KENTRMNRSVDIFSCGCLFYYVLSGGLHPFGDTYRRQANIISGECNLD----TLPQAECP 760 Query: 712 VVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPL 771 VV + +I MI PS RP + L++P+FW +Q L F QDVSD++E + L Sbjct: 761 VVARDIIEMMIDPDPSKRPTAQMALQHPLFWNRQRQLAFFQDVSDRIEKESDDSPLLDAL 820 Query: 772 ERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSL 831 +R RV+RGDW+V +C+ + DLR RTY G ++ LLRA+RNKKHHYREL +V+ SL Sbjct: 821 QRDSIRVVRGDWKVHICQALQDDLRRFRTYNGTQLRDLLRALRNKKHHYRELPDEVKRSL 880 Query: 832 GKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYYPR 872 G +PD +V Y+ +RFP LL H + M+ ++E + TYY R Sbjct: 881 GTIPDEYVRYFTSRFPRLLMHTYNVMRICQNETVFHTYYYR 921 Score = 195 bits (476), Expect = 4e-48 Identities = 119/328 (36%), Positives = 174/328 (53%), Gaps = 36/328 (10%) Query: 35 FLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGILYTGKKSDTWFMIDPL 94 F+PDP+ G LY +G D LKKLPFTIPELV +PCRS DGILYTG+K+D WF +DP Sbjct: 50 FIPDPKDGSLYAFGNTLDG--LKKLPFTIPELVRASPCRSNDGILYTGRKTDVWFAVDPD 107 Query: 95 TGFREHVSGFDKSKIFKSDDENTC--NSEKKKGIYVARTEYNILMHDSKNVNHKWNVTFF 152 TG ++ D + E C K ++ RTEY I M+D K +WN TF Sbjct: 108 TGIKQQTLRLDGT-------ETVCPIMPNKAAPMFFGRTEYTITMYDHKTREKRWNATFN 160 Query: 153 DYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTPVVAAYLLDRDGLI 212 DY S + +D+ DYG H S+S+G ++ + TG++ W+ NFG+PVV Y D DGL Sbjct: 161 DY-STHLAQDI--DYGFHHMASSSDGFTVTMESSTGEIQWTRNFGSPVVGVYKFDGDGLH 217 Query: 213 SVPFNSIGDDTLDHIMED--------AKTLSNGKGLKNSNIELYPTLYVGEHNHGLYALS 264 + N I +TL+ ++ + ++ L + PTLY+GEH+ GLYAL Sbjct: 218 RLKINHIASETLNVLISGNSSADKVVLQLINTVPPLSTLFVSCRPTLYIGEHSGGLYALP 277 Query: 265 SLVDKNTITISTGHQPLLIEGPSTE------TLKTNAPRYEPIKNI----HYKLSDLNLH 314 SLV++ + + Q +L+EGP T N P + +++ L + Sbjct: 278 SLVEEGSPLVEA--QVMLLEGPKKHIRVPRGTKGANTPSKDSNQDLPPPPRRPLQQPKVL 335 Query: 315 VSAPYLLLGHYKVPELTTSWI--PHLPN 340 LLLGH++VP + + + H+P+ Sbjct: 336 EPKAALLLGHHQVPSIASPQLQMTHIPD 363 >UniRef50_Q6GPM2 Cluster: MGC83537 protein; n=4; Tetrapoda|Rep: MGC83537 protein - Xenopus laevis (African clawed frog) Length = 958 Score = 435 bits (1071), Expect = e-120 Identities = 215/401 (53%), Positives = 276/401 (68%), Gaps = 5/401 (1%) Query: 473 EMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAH 532 E+++GKI+F VLG G GT V+RGTFD R VAVKR+L E F ADREV LLRESD H Sbjct: 554 EIRVGKISFSPKDVLGHGAGGTCVFRGTFDDRAVAVKRILSESFILADREVQLLRESDEH 613 Query: 533 AHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592 +V+RYYCT+ DK F YIALELC+ATLQ+Y++ +DSV +L Q GL+HLHS+ Sbjct: 614 PNVIRYYCTDSDKLFCYIALELCAATLQEYIKNPEFHRSGLDSVTLLHQTMSGLAHLHSL 673 Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652 +IVHRD+KP N+L+S PS G+VRA+ISDFGL KKL++GR SFS RSG+ GT+GWIAPE+ Sbjct: 674 NIVHRDLKPCNILISYPSAHGKVRALISDFGLCKKLSVGRNSFSLRSGIPGTEGWIAPEV 733 Query: 653 ING---ERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEE 709 + + T ++DIFS GCVFYYVLSKGQHPFGD LRRQ+NIL+G Y+L L Sbjct: 734 LRDRPKQNPTAAVDIFSAGCVFYYVLSKGQHPFGDNLRRQSNILSGSYSLPKLQD--DTH 791 Query: 710 ELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEH 769 E VV + L+ MI++ P RP + +L +P FW L F QDVSD++E Sbjct: 792 ENVVARHLVEMMINSDPLLRPSSQNVLIHPFFWTPAKRLQFFQDVSDRIEKEPVESPIVV 851 Query: 770 PLERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRD 829 LE V+R +WR+ + + DLR R+YRG+ V LLRA+RNKKHHY EL +DVR+ Sbjct: 852 ALESDARPVVRVNWRLHISVPLQTDLRKFRSYRGNSVRDLLRAMRNKKHHYHELPADVRE 911 Query: 830 SLGKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYY 870 +LG +PD FVSY+ +RFP LL H + M++ E QTYY Sbjct: 912 TLGSIPDEFVSYFTSRFPHLLLHTYQAMKKCSPERQFQTYY 952 Score = 202 bits (493), Expect = 4e-50 Identities = 113/318 (35%), Positives = 184/318 (57%), Gaps = 24/318 (7%) Query: 20 PVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGIL 79 PV++VP + P FLPDP G LY G R +++ L KLPFTI ELV ++PCRS+DGIL Sbjct: 65 PVIQVPLYVSE--PAFLPDPSDGSLYILGGR-NKEGLMKLPFTIQELVQSSPCRSSDGIL 121 Query: 80 YTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHD 139 YTGKK D WF++DP +G ++ + S E C S +Y+ RT+Y I M+D Sbjct: 122 YTGKKQDAWFVVDPNSGEKQTTLSTESS-------EGLCPSSPL--LYIGRTQYMITMYD 172 Query: 140 SKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTP 199 +K+ +WN TF DY+ A D DY HFTST +G++++ DR +G+++W N+G+P Sbjct: 173 TKSRELRWNATFHDYS--APMCDESYDYKMAHFTSTGDGQLVTADRDSGEVLWMQNYGSP 230 Query: 200 VVAAYLLDRDGLISVPFNSIGDDTLDHI---MEDAKTLSNG----KGLKNSNIELYPTLY 252 VV ++ +D L +P ++ +TL ++ D + + + L ++ L P+LY Sbjct: 231 VVGLFMWHQDSLRRIPHLNVASETLRYLTFHSHDIRLIKWNYQAVQQLSSTKTHLLPSLY 290 Query: 253 VGEHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTE--TLKTNAPRYEPIKNIHYKLSD 310 VG+H G YA SS++ + + G ++GP+T+ TLK + +++ N + Sbjct: 291 VGKHVTGFYATSSMIHEGVALVPRGITLARVDGPTTQDVTLK-ESTKFDVTSNTDVRYPQ 349 Query: 311 LNLHVSAPYLLLGHYKVP 328 ++ + +LL+GH+++P Sbjct: 350 GSVISAHQWLLIGHHELP 367 >UniRef50_Q09499 Cluster: Serine/threonine-protein kinase/endoribonuclease ire-1 precursor (Inositol-requiring protein 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]; n=2; Caenorhabditis|Rep: Serine/threonine-protein kinase/endoribonuclease ire-1 precursor (Inositol-requiring protein 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] - Caenorhabditis elegans Length = 967 Score = 402 bits (989), Expect = e-110 Identities = 201/408 (49%), Positives = 267/408 (65%), Gaps = 7/408 (1%) Query: 467 MEIGEGEMKIG-KITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVAL 525 +EI EG M +G K+ + +LG GCEGT VYRGTFD R+VAVKR++ E FA RE L Sbjct: 503 IEIPEGWMAVGSKLMYSPSDILGTGCEGTVVYRGTFDGREVAVKRVVSEFVKFAHREADL 562 Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVE-KKLNFECKIDSVEILRQATM 584 LRESD H HV+RY+C E D QFRY+ALELC A+L DYVE K++ I +I++QAT Sbjct: 563 LRESDTHPHVIRYFCMESDSQFRYLALELCIASLNDYVEQKEVQQNVTIALRDIMKQATD 622 Query: 585 GLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSR--RSGVT 642 GL+HLH+ IVHRD+KP NVL++M S GE+RA+ISDFGL K++ G+ S SR SG+ Sbjct: 623 GLAHLHASKIVHRDMKPQNVLITMASQRGEMRAVISDFGLCKRVQPGKNSISRGIASGLA 682 Query: 643 GTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHL 702 GTDGWIAPE++ T+ +DIFSLGC+FYYVL+ G HPFG L RQANI+ G+Y L Sbjct: 683 GTDGWIAPEVLISASTSYPVDIFSLGCIFYYVLTSGTHPFGKSLHRQANIVNGEYT---L 739 Query: 703 DKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCA 762 +K+ ++ + LI +M++ +P R + +L +P FW + L + DVSD+VE Sbjct: 740 NKLADLDDWSLADDLISSMLNVEPLHRLTADAVLNHPFFWTSEKRLAYFSDVSDRVEKEE 799 Query: 763 CGFGAEHPLERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRE 822 +E V+ G WR ++C + DLR RTY+ V LLRA+RNKKHHYRE Sbjct: 800 DNSPVVRRIETDARIVVCGGWREKICDALKEDLRKFRTYKSFSVRDLLRAMRNKKHHYRE 859 Query: 823 LESDVRDSLGKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYY 870 L DVR SLG +PD F+ Y+ +RFP LL HV+ + E + + YY Sbjct: 860 LPEDVRQSLGDIPDQFLHYFTSRFPRLLLHVYKATEYCSGEAVFKRYY 907 Score = 191 bits (466), Expect = 7e-47 Identities = 119/334 (35%), Positives = 179/334 (53%), Gaps = 33/334 (9%) Query: 19 QPVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGI 78 +PV++ PS FLP+P G LY LKKLPF IP+LV +PC+ DGI Sbjct: 71 EPVLRSPSAVKQGFT-FLPNPLDGSLYVL----KNSSLKKLPFNIPQLVHASPCKGNDGI 125 Query: 79 LYTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMH 138 LY G K D WF IDP TG + + + + C + +K+ I++ RTEY + M Sbjct: 126 LYAGSKKDVWFGIDPKTGLKVET-------LSSASADRICPANQKQTIFLGRTEYRVSMF 178 Query: 139 DSKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGT 198 D KN WN TF DY++ + + +N + H+ S+S+G +++FDR+TG++ W + Sbjct: 179 DEKNRGKTWNATFNDYSAHLLPE--VNTWPFKHYASSSHGYILTFDRETGEMRWEQDLKQ 236 Query: 199 PVVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLKNSNI----------ELY 248 PVVA YLL DGL +PF +G +T++++ ++ T+ + N + + Sbjct: 237 PVVALYLLRDDGLHKLPFEVMGKETMENVAKNIFTVDQWPTVLGVNAADPQTTSLTNQFF 296 Query: 249 PTLYVGEHNHGLYALSSLVDKNTITISTG-HQPLLIEGPS----TETLKTN--APRYEPI 301 P L+VGE + GLYA+ +LVD TIT S P L+EGP+ TE K PR I Sbjct: 297 PALFVGESSFGLYAIEALVDHQTITYSPKLLGPPLLEGPAPIALTEMEKEEYLPPRRPII 356 Query: 302 KNIHYKLSDLNLHVSAPYLLLGHYKVPELTTSWI 335 +NI ++ + YLLLG++ P +T + I Sbjct: 357 RNIPPSIT--HKTSDGEYLLLGYHDRPMMTMATI 388 >UniRef50_A5YM46 Cluster: ERN2 protein; n=1; Homo sapiens|Rep: ERN2 protein - Homo sapiens (Human) Length = 874 Score = 400 bits (986), Expect = e-110 Identities = 201/399 (50%), Positives = 260/399 (65%), Gaps = 5/399 (1%) Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535 +GKI+F VLG+G GTFV+RG F+ R VAVKRLL ECF REV LL+ESD H +V Sbjct: 463 VGKISFNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQLLQESDRHPNV 522 Query: 536 VRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIV 595 +RY+CTER QF YIALELC A+LQ+YVE ++ +L+Q GL+HLHS+ IV Sbjct: 523 LRYFCTERGPQFHYIALELCRASLQEYVENPDLDRGGLEPEVVLQQLMSGLAHLHSLHIV 582 Query: 596 HRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN- 654 HRD+KP N+L++ P G R ++SDFGL KKL GR SFS SG+ GT+GW+APE++ Sbjct: 583 HRDLKPGNILITGPDSQGLGRVVLSDFGLCKKLPAGRCSFSLHSGIPGTEGWMAPELLQL 642 Query: 655 --GERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712 + T+++DIFS GCVFYYVLS G HPFGD L RQANILTG L HL++ + ++ V Sbjct: 643 LPPDSPTSAVDIFSAGCVFYYVLSGGSHPFGDSLYRQANILTGAPCLAHLEEEVHDK--V 700 Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLE 772 V + L+ AM+S P RP +L +P FW + L F QDVSD +E + LE Sbjct: 701 VARDLVGAMLSPLPQPRPSAPQVLAHPFFWSRAKQLQFFQDVSDWLEKESEQEPLVRALE 760 Query: 773 RGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLG 832 GG V+R +W + + DLR R+Y+G V LLRA+RNKKHHYREL +VR +LG Sbjct: 761 AGGCAVVRDNWHEHISMPLQTDLRKFRSYKGTSVRDLLRAVRNKKHHYRELPVEVRQALG 820 Query: 833 KLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYYP 871 ++PDGFV Y+ RFP LL H M+ E + YYP Sbjct: 821 QVPDGFVQYFTNRFPRLLLHTHRAMRSCASESLFLPYYP 859 Score = 147 bits (355), Expect = 2e-33 Identities = 100/320 (31%), Positives = 157/320 (49%), Gaps = 32/320 (10%) Query: 20 PVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGIL 79 PV++ P + FL DP G LY G + QQ L KLPFTIPELV +PCRS+DG+ Sbjct: 68 PVIEGPMYVTEMA--FLSDPADGSLYILGTQ-KQQGLMKLPFTIPELVHASPCRSSDGVF 124 Query: 80 YTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHD 139 YTG+K D WF++DP +G ++ T +Y+ RT+Y + MHD Sbjct: 125 YTGRKQDAWFVVDPESG--------------ETQMTLTTEGPSTPRLYIGRTQYTVTMHD 170 Query: 140 SKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTP 199 + +WN T+ Y++ M Y + H S G +++ D +G ++W+ + G P Sbjct: 171 PRAPALRWNTTYRRYSAPPMDGSP-GKYMS-HLASCGMGLLLTVDPGSGTVLWTQDLGVP 228 Query: 200 VVAAYLLDRDGLISVPFNSIGDDTL-------DHIMEDAKTLSNGKGLKNS-NIELYPTL 251 V+ Y +DGL +P ++ DTL HI A + L ++ + +L TL Sbjct: 229 VMGVYTWHQDGLRQLPHLTLARDTLHFLALRWGHIRLPASGPRDTATLFSTLDTQLLMTL 288 Query: 252 YVGEHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTE--TLKTNAPRY-EPIKNIHYKL 308 YVG+ G Y +LV + G +GP+T+ TL+ + R P + Y Sbjct: 289 YVGKDETGFYVSKALVHTGVALVPRGLTLAPADGPTTDEVTLQVSGEREGSPSTAVRYPS 348 Query: 309 SDLNLHVSAPYLLLGHYKVP 328 + L + +LL+GH+++P Sbjct: 349 GSVAL--PSQWLLIGHHELP 366 >UniRef50_Q76MJ5 Cluster: Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (hIRE2p) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]; n=19; Euteleostomi|Rep: Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (hIRE2p) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] - Homo sapiens (Human) Length = 925 Score = 398 bits (981), Expect = e-109 Identities = 202/399 (50%), Positives = 259/399 (64%), Gaps = 5/399 (1%) Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535 +GKI+F VLG G GTFV+RG F+ R VAVKRLL ECF REV LL+ESD H +V Sbjct: 514 VGKISFNPKDVLGHGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQLLQESDRHPNV 573 Query: 536 VRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIV 595 +RY+CTER QF YIALELC A+LQ+YVE ++ +L+Q GL+HLHS+ IV Sbjct: 574 LRYFCTERGPQFHYIALELCRASLQEYVENPDLDRGGLEPEVVLQQLMSGLAHLHSLHIV 633 Query: 596 HRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN- 654 HRD+KP N+L++ P G R ++SDFGL KKL GR SFS SG+ GT+GW+APE++ Sbjct: 634 HRDLKPGNILITGPDTQGLGRVVLSDFGLCKKLPAGRCSFSLHSGIPGTEGWMAPELLQL 693 Query: 655 --GERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712 T+++DIFS GCVFYYVLS G HPFGD L RQANILTG L HL++ + ++ V Sbjct: 694 LPPNSPTSAVDIFSAGCVFYYVLSGGSHPFGDSLYRQANILTGVPCLAHLEEEVHDK--V 751 Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLE 772 V + L+ AM+S P ARP +L +P FW + L F QDVSD +E + LE Sbjct: 752 VARDLVAAMLSLLPQARPSAPQVLAHPFFWSRAKQLQFFQDVSDWLEKESEQEPLMRALE 811 Query: 773 RGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLG 832 GG V+R +W + + DLR R+Y+G V LLRA+RNKKHHYREL +VR +LG Sbjct: 812 AGGCTVVRDNWHEHISMPLQIDLRKFRSYKGTSVRDLLRAVRNKKHHYRELPVEVRQALG 871 Query: 833 KLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYYP 871 ++PDGFV Y+ RFP LL H M+ E + YYP Sbjct: 872 QVPDGFVQYFTNRFPQLLLHTHRVMRSCASESLFLPYYP 910 Score = 147 bits (355), Expect = 2e-33 Identities = 106/345 (30%), Positives = 166/345 (48%), Gaps = 35/345 (10%) Query: 20 PVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGIL 79 PV++ P + FL DP G LY G + Q L KLPFTIPELV +PCRS+DG+ Sbjct: 68 PVIEGPMYVTEMA--FLSDPADGSLYILGTQ-KQLGLMKLPFTIPELVHASPCRSSDGVF 124 Query: 80 YTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHD 139 YTG+K D WF++DP +G ++ T +Y+ RT+Y + MHD Sbjct: 125 YTGRKQDAWFVVDPESG--------------ETQMTLTTAGPSTPRLYIGRTQYTVTMHD 170 Query: 140 SKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTP 199 + +WN T+ Y++ M Y + H S G +++ D ++G ++W+ + G P Sbjct: 171 PRAPALRWNTTYRRYSAPPMDGSP-GKYMS-HLASCGMGLLLTVDPESGAVLWTQDLGMP 228 Query: 200 VVAAYLLDRDGLISVPFNSIGDDTL-------DHIMEDAKTLSNGKGLKNS-NIELYPTL 251 V+ Y +DGL +P ++ DTL HI A + L ++ + +L TL Sbjct: 229 VMGVYTWHQDGLRQLPHLTLARDTLHFLALRWGHIRLPASGPQDTATLFSALDTQLLMTL 288 Query: 252 YVGEHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTE--TLKTNAPRY-EPIKNIHYKL 308 YVG+ G Y +LV + G +GP+T+ TL+ + R P + Y Sbjct: 289 YVGKDETGFYVSKALVHTGVALVPRGLTLAPTDGPTTDEVTLQVSGEREGSPSTAVRYPS 348 Query: 309 SDLNLHVSAPYLLLGHYKVPEL--TTSWIPH-LPNSNVLNLRDPQ 350 + L + +LL+GH+++P + TT H P S R P+ Sbjct: 349 GSVAL--PSQWLLIGHHELPPVLHTTMLRVHPTPGSGTAETRPPE 391 >UniRef50_O94537 Cluster: Serine/threonine-protein kinase ppk4 precursor; n=1; Schizosaccharomyces pombe|Rep: Serine/threonine-protein kinase ppk4 precursor - Schizosaccharomyces pombe (Fission yeast) Length = 1072 Score = 298 bits (732), Expect = 4e-79 Identities = 164/412 (39%), Positives = 238/412 (57%), Gaps = 31/412 (7%) Query: 471 EGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESD 530 +G + + +T + V+G G GT VYRG ++ R+VAVKR+L E + A RE+ LL++SD Sbjct: 645 DGSVTVNSLTVYPE-VIGYGSHGTIVYRGVYEDREVAVKRVLMEFYDLASREITLLQQSD 703 Query: 531 AHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFE---CKIDSVEILRQATMGLS 587 H ++VRYYC ++ QF YI +ELC L D +EK + ++ ID V +L Q G+S Sbjct: 704 NHPNIVRYYCKQKSDQFLYIVIELCKCNLSDLIEKPIAYDDLFKSIDLVSLLYQIAFGVS 763 Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTG----EVRAMISDFGLSKKLNIGRVSFSRRS-GVT 642 HLHS+D+VHRD+KP N+LL + + VRA+ISDFGLSKKL+ + S + Sbjct: 764 HLHSLDLVHRDLKPQNILLVVNNSPNLSKTRVRALISDFGLSKKLDFNQSSLRNTTFEAA 823 Query: 643 GTDGWIAPEMING------------------ERTTTSIDIFSLGCVFYYVLSKGQHPFGD 684 G+ GW +PE+++G + + + DIF+LGC+FYY L+ G HPFG Sbjct: 824 GSYGWRSPEILSGSLSQQSKEIQVKTREGRIRQASHATDIFALGCIFYYTLTGGMHPFGS 883 Query: 685 VLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCK 744 + NIL G+Y L HL + E V+ LI MI+ +PS RP E +L +P+FW Sbjct: 884 HYDCEGNILKGNYCLVHLQSL--GECGVLAADLIEDMIAFEPSKRPTIEVVLNHPLFWDY 941 Query: 745 QSILNFLQDVSD--QVESCACGFGAEHPLERGGARVLRGDWRVRVCRVVAGDLRTRRTYR 802 L+FL DVSD +VE LE V+ +W + + +L R Y Sbjct: 942 AKKLDFLIDVSDRFEVEERDPPSPLLQMLENNSKSVIGENWTTCLHSSLVDNLGKYRKYD 1001 Query: 803 GDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVW 854 G ++ +LR +RNK+HHY++L VR LG LPDGF SY++ +FP+LL H + Sbjct: 1002 GSKILDILRVLRNKRHHYQDLPESVRRVLGDLPDGFTSYFVEKFPMLLLHCY 1053 >UniRef50_P32361 Cluster: Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]; n=3; Saccharomyces cerevisiae|Rep: Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] - Saccharomyces cerevisiae (Baker's yeast) Length = 1115 Score = 276 bits (677), Expect = 2e-72 Identities = 166/438 (37%), Positives = 244/438 (55%), Gaps = 52/438 (11%) Query: 483 TDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTE 542 ++++LG G GT V++G+F R VAVKR+L + A E+ LL ESD H +V+RYYC+E Sbjct: 676 SEKILGYGSSGTVVFQGSFQGRPVAVKRMLIDFCDIALMEIKLLTESDDHPNVIRYYCSE 735 Query: 543 RDKQFRYIALELCSATLQDYVEKK------LNFECKIDSVEILRQATMGLSHLHSMDIVH 596 +F YIALELC+ LQD VE K L + + + + +LRQ G++HLHS+ I+H Sbjct: 736 TTDRFLYIALELCNLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIH 795 Query: 597 RDVKPHNVLLSMPS--------GTGEVRAMISDFGLSKKLNIGRVSF-SRRSGVTGTDGW 647 RD+KP N+L+S S G +R +ISDFGL KKL+ G+ SF + + +GT GW Sbjct: 796 RDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGW 855 Query: 648 IAPEMI---------------NGERTTTSIDIF----------------SLGCVFYYVLS 676 APE++ + T S D F S+GCVFYY+LS Sbjct: 856 RAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILS 915 Query: 677 KGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVV-IKILIRAMISAKPSARPPCETI 735 KG+HPFGD R++NI+ G ++LD + K L + L+ LI MI P RP + Sbjct: 916 KGKHPFGDKYSRESNIIRGIFSLDEM-KCLHDRSLIAEATDLISQMIDHDPLKRPTAMKV 974 Query: 736 LKYPMFWCKQSILNFLQDVSD--QVESCACGFGAEHPLERGGARVL-RGDWRVRVCRVVA 792 L++P+FW K L FL VSD ++E+ + G V+ GDW V+ + Sbjct: 975 LRHPLFWPKSKKLEFLLKVSDRLEIENRDPPSALLMKFDAGSDFVIPSGDWTVKFDKTFM 1034 Query: 793 GDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPH 852 +L R Y ++ LLRA+RNK HH+ +L D+ + +G +PDGF Y+ RFP LL Sbjct: 1035 DNLERYRKYHSSKLMDLLRALRNKYHHFMDLPEDIAELMGPVPDGFYDYFTKRFPNLLIG 1094 Query: 853 VWLQMQQ-YRDEDILQTY 869 V++ +++ D+ IL+ + Sbjct: 1095 VYMIVKENLSDDQILREF 1112 >UniRef50_Q6FUI3 Cluster: Similar to sp|P32361 Saccharomyces cerevisiae YHR079c IRE1; n=1; Candida glabrata|Rep: Similar to sp|P32361 Saccharomyces cerevisiae YHR079c IRE1 - Candida glabrata (Yeast) (Torulopsis glabrata) Length = 1036 Score = 276 bits (676), Expect = 2e-72 Identities = 162/434 (37%), Positives = 244/434 (56%), Gaps = 46/434 (10%) Query: 483 TDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTE 542 +D+VLG G GT VY G F +R VAVKR+L + + A +E+ LL ESD H +VVRYYC+E Sbjct: 603 SDKVLGYGSSGTVVYEGKFQERSVAVKRMLVDFYDIASKEIELLSESDEHPNVVRYYCSE 662 Query: 543 RDKQFRYIALELCSATLQDYVEKK--LNFECKI---DSVEILRQATMGLSHLHSMDIVHR 597 +F YIALELC + L+ +E + E ++ + V+IL Q T G+++LHS++I+HR Sbjct: 663 ETSKFLYIALELCDSNLEQLIETNNVMRHEQRLKDYELVDILAQITQGIAYLHSLNIIHR 722 Query: 598 DVKPHNVLLSMP----------SGTGEVRAMISDFGLSKKLNIGRVSFSRR-SGVTGTDG 646 D+KP N+L+S +G + R M+SDFGL KKL+ + SF GT G Sbjct: 723 DIKPQNILISKSKKRLQKPTTGNGNNKTRIMLSDFGLCKKLDFEQSSFKTNIKNAAGTVG 782 Query: 647 WIAPEMI----NG---------------------ERTTTSIDIFSLGCVFYYVLSKGQHP 681 W+APE++ N R T +IDIFSLGCVFYYVLS G HP Sbjct: 783 WMAPELLIEDENSNKISVSQEIEKIDEVYDPYLRRRLTKAIDIFSLGCVFYYVLSGGSHP 842 Query: 682 FGDVLRRQANILTGDYNLDHLDKILPEEELVVIKI-LIRAMISAKPSARPPCETILKYPM 740 FGD R+ I+ G + L + + ++ LV + ++ +++ PS RP E +L++P Sbjct: 843 FGDKYTREFQIINGKKDFKGLKENMKDKSLVYEAVNILNQLLNHDPSNRPSAEVVLRHPF 902 Query: 741 FWCKQSILNFLQDVSDQVESCACGFGAE--HPLERGGARVL-RGDWRVRVCRVVAGDLRT 797 FW K L+FL VSD++E +E LE R++ DW + +L Sbjct: 903 FWSKAKKLDFLLKVSDRLEIETRDPPSELLTKLENRSRRIIPHHDWCKYLDPEFFENLMK 962 Query: 798 RRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHV-WLQ 856 R Y+ ++V LLRAIRN HHY +L +R+ +G +P+GF Y+ ++P LL V +L Sbjct: 963 YRKYQKEKVVDLLRAIRNVYHHYNDLPEHIREKMGSIPNGFYDYFSEKYPHLLMEVHFLI 1022 Query: 857 MQQYRDEDILQTYY 870 + ++E++ + ++ Sbjct: 1023 NKTIKNENLFEEFF 1036 >UniRef50_Q4WKP8 Cluster: Protein kinase and ribonuclease Ire1, putative; n=7; Eurotiomycetidae|Rep: Protein kinase and ribonuclease Ire1, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 1165 Score = 269 bits (660), Expect = 2e-70 Identities = 173/441 (39%), Positives = 248/441 (56%), Gaps = 63/441 (14%) Query: 471 EGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESD 530 +G ++IG++ +D VLG G GT VYRG+FD RDVAVKR+L E + A EV LL+ESD Sbjct: 701 DGVLQIGRLRVFSDVVLGHGSHGTVVYRGSFDGRDVAVKRMLVEFYDIASHEVGLLQESD 760 Query: 531 AHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNF----ECKIDSVEILRQATMGL 586 H +V+RY+C E+ F YIALELC A+LQD +E+ ++ + +D +ILRQ G+ Sbjct: 761 DHNNVIRYFCREQAAGFLYIALELCPASLQDLIERPGDYPQLVQGGLDMPDILRQIIAGV 820 Query: 587 SHLHSMDIVHRDVKPHNVLLSMPSG-TG--EVRAMISDFGLSKKLNIGRVSF-SRRSGVT 642 +LHS+ IVHRD+KP N+L++MP G TG +R +ISDFGL KKL+ + SF + + Sbjct: 821 RYLHSLKIVHRDLKPQNILVAMPRGRTGSRSLRLLISDFGLCKKLDDNQSSFRATTAHAA 880 Query: 643 GTDGWIAPEMI----------NGERTTT------------------SIDIFSLGCVFYYV 674 GT GW APE++ GE T +IDIFSLGCVFYYV Sbjct: 881 GTSGWRAPELLVDDDNRSAIQGGESQHTESSEPAVVDPQTNRRATRAIDIFSLGCVFYYV 940 Query: 675 LSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPS----- 727 L++G HPF R+ANI+ G++NLD L ++ + LIR+M+S P Sbjct: 941 LTRGSHPFDKNGKFMREANIVKGNFNLDELQRL--GDYAFEADDLIRSMLSLDPRKRLAP 998 Query: 728 --------------ARPPCETILKYPMFWCKQSILNFLQDVSD--QVESCACGFGAEHPL 771 RP +L +P FW L+FL DVSD + E A L Sbjct: 999 LCSSLAFRLFTDLFPRPDASAVLMHPFFWNPSDRLSFLCDVSDHFEFEPRDPPSDALLCL 1058 Query: 772 ERGGARVL--RGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRD 829 E RV+ D+ + + +L +R Y G ++ LLRA+RNK++HY ++ + ++ Sbjct: 1059 ESVACRVMGPEMDFLRLLPKDFKDNLGKQRKYTGSKMLDLLRALRNKRNHYNDMPAHLKA 1118 Query: 830 SLGKLPDGFVSYWLTRFPLLL 850 +G LP+G++++W RFP LL Sbjct: 1119 HIGGLPEGYLNFWTVRFPSLL 1139 Score = 50.4 bits (115), Expect = 2e-04 Identities = 46/177 (25%), Positives = 74/177 (41%), Gaps = 15/177 (8%) Query: 42 GFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTD-GILYTGKKSDTWFMIDPLTG---- 96 G LY Y P G L+KL T+ ELV P TD + YT +K T + +D TG Sbjct: 175 GNLYIYSP-GPDAGLQKLGLTVKELVEQTPYSGTDPAVTYTARKETTLYTVDARTGNILQ 233 Query: 97 -FREH---VSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHDSKNVNHKWNVTFF 152 F SG K+ D E + + R EY + + +++ + + + Sbjct: 234 VFSSRGPITSGHGCRKVDGFDLEAEECDTPSGTLVLGRVEYAVAIQNTETGDPICTLKYS 293 Query: 153 DYTSLAMGKDMLNDY----GTIHFTSTSNGRVMSFDRKTGDLV-WSHNFGTPVVAAY 204 ++T+ D+ + Y H S +G V+ FD D ++ F +PVV + Sbjct: 294 EWTANNRDMDLQSQYFRTMDQSHIYSMHDGVVLGFDHSRMDRPRYTQRFSSPVVRVF 350 >UniRef50_A5DU16 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 1286 Score = 269 bits (660), Expect = 2e-70 Identities = 168/454 (37%), Positives = 250/454 (55%), Gaps = 65/454 (14%) Query: 483 TDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTE 542 +D++LG G GT V++G+F+ R VAVKR+L + + A+ EV LL+ESD H +V+RY+C++ Sbjct: 838 SDKILGYGSHGTVVFQGSFENRPVAVKRMLLDFYDVANHEVRLLQESDDHPNVIRYFCSQ 897 Query: 543 --RDKQFRYIALELCSATLQDYVEKKLNFE--CKIDSVEILRQATMGLSHLHSMDIVHRD 598 ++F YIALELC TL+D +EK F C EIL Q GL +LHS+ IVHRD Sbjct: 898 SSESEKFLYIALELCLCTLEDIIEKPQRFADLCIPKRNEILYQLASGLHYLHSLKIVHRD 957 Query: 599 VKPHNVLL---------------SMPSGTGE--------VRAMISDFGLSKKLNIGRVSF 635 +KP N+L+ S+ S G VR +ISDFGL KKL+ + SF Sbjct: 958 IKPQNILVADMKKTYQIKKNQSSSLSSSLGNENHEEHNNVRLLISDFGLCKKLDNDQSSF 1017 Query: 636 --SRRSGVTGTDGW-------------IAPEMIN----------------GERTTTSIDI 664 + ++ +GT GW I+P+ I+ G+R T +IDI Sbjct: 1018 RATTQNAASGTSGWRAPELLLHHDLLEISPDSISSVHSAGGIMDPNISSSGKRLTKAIDI 1077 Query: 665 FSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISA 724 FSLGCVF+Y+L+ G HPFGD R+ NI+ G+Y+L L + P ++ + LI +I A Sbjct: 1078 FSLGCVFFYILTNGSHPFGDRYLREGNIIKGEYDLSLLIQRCPNDKYESVD-LISKLIDA 1136 Query: 725 KPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAE--HPLERGGARVLRGD 782 P+ RP I+K+P+FW L F+ VSD V+ + LE A+V D Sbjct: 1137 NPANRPNASVIMKHPLFWSNHKRLEFIIKVSDTVDRVNRKEPSALLDSLESHAAKVHNMD 1196 Query: 783 WRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYW 842 WR + + + +L T R Y +++A L+RAIRNK HY EL +++ +G PDGF Y+ Sbjct: 1197 WRSALDQELVDNLGTYRMYGTEKLADLIRAIRNKCRHYDELPKSLQEKIGTFPDGFYKYF 1256 Query: 843 LTRFPLLLPHVWLQMQQYRDEDILQTYYPRTYVF 876 RF PH+ +++ + ++++ Y R + F Sbjct: 1257 NDRF----PHLLMELYYFAEQNLKDEYEYRLFYF 1286 Score = 45.6 bits (103), Expect = 0.007 Identities = 34/157 (21%), Positives = 64/157 (40%), Gaps = 7/157 (4%) Query: 56 LKKLPFTIPELVANAPCR-STDGILYTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDD 114 L KLP +I LV +P S D +YTG + + ++ TG + G + Sbjct: 187 LNKLPTSIKTLVMESPFSLSGDDKIYTGTRKTALYSLNIHTGEIKSSFGNRDEECPVPTS 246 Query: 115 ENTCNSEKKKGIYVARTEYNILMHDSKNVNHKWNVTFFDYTSLAMGKDML----NDYGTI 170 + I + +T Y + +H N N WNVT+ + + D++ + Sbjct: 247 ALPPRDAEDDTIMIGKTRYELSIHSKSNSNVVWNVTYSQWVPNNIDNDLIMQNQESLDKL 306 Query: 171 HFTSTSNGRVMSFDRKTGDLVWSHNFGTPVVAAYLLD 207 +FT + +++ ++ G +W P +A + D Sbjct: 307 YFTPFHDRSLLAINKDMGTPIWISKL--PALAVNIFD 341 >UniRef50_Q4P7S2 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 1442 Score = 267 bits (655), Expect = 9e-70 Identities = 166/425 (39%), Positives = 234/425 (55%), Gaps = 39/425 (9%) Query: 483 TDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTE 542 +D+VLG G GT V+RGTF R VAVKRLL + A +EV+LL +D H +V+RY+ E Sbjct: 1013 SDEVLGYGSSGTVVFRGTFQGRAVAVKRLLRDFVHVASKEVSLLESADNHPNVIRYFYKE 1072 Query: 543 RDKQFRYIALELCSATLQDYVEKKLNFECKIDSVE---ILRQATMGLSHLHSMDIVHRDV 599 F +IALELC A+L + VE+ ++ + +E L+Q GL HLHS+ IVHRD+ Sbjct: 1073 LTPSFLFIALELCPASLAEVVERPADYRDLSNLLEPKRALQQIASGLRHLHSLSIVHRDI 1132 Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLN-IGRVSFSRR-SGVTGTDGWIAPEMINGE- 656 KP N+L++ + ++ ++SDFGLSK+L+ + + SFS+ + GT GW APE++ G+ Sbjct: 1133 KPQNILVATSTSGKHLKMLLSDFGLSKRLDGMAQTSFSQTVNNPGGTVGWRAPEILRGDV 1192 Query: 657 ----------------RTTTS----------IDIFSLGCVFYYVLSKGQHPFGDVLRRQA 690 R+T+S +DIF+LGC+ YYVLS G HPFG R+ Sbjct: 1193 NLDAGSESESSMGNNPRSTSSREEKQRLTRAVDIFALGCLAYYVLSNGDHPFGSRFEREM 1252 Query: 691 NILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNF 750 NI+ +L LD + EE + L+ M+S P RP L +P FW LNF Sbjct: 1253 NIIRKRVDLSRLDGL--GEEGHEAQDLVLRMVSHDPRHRPSAAEALTHPYFWDANKRLNF 1310 Query: 751 LQDVSDQVESCACG--FGAEHPLERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAH 808 LQD SD+ E A LE VL DW R R+ +L R Y V Sbjct: 1311 LQDASDRFEIMDKDPPTPALVLLESKARNVLGTDWHRRCDRMFLENLGKFRKYDPTSVQD 1370 Query: 809 LLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVW---LQMQQYRDEDI 865 LLRA+RNKKHHY++L ++ LG LPDG+++Y+ RFP L HV+ + R E + Sbjct: 1371 LLRAMRNKKHHYQDLPGTLKKVLGSLPDGYLNYFTRRFPELFLHVYNTIVDQPLIRTEPV 1430 Query: 866 LQTYY 870 + Y+ Sbjct: 1431 FREYF 1435 >UniRef50_A6SFQ8 Cluster: Serine/threonine-protein kinase; n=1; Botryotinia fuckeliana B05.10|Rep: Serine/threonine-protein kinase - Botryotinia fuckeliana B05.10 Length = 1184 Score = 266 bits (653), Expect = 1e-69 Identities = 164/427 (38%), Positives = 234/427 (54%), Gaps = 43/427 (10%) Query: 468 EIGEGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLR 527 E+ ++IG + ++++G G GT V+ G FD R VAVKR+L + + A +E LLR Sbjct: 738 EVSGSRIRIGALEVDQNKLVGTGSNGTMVFEGKFDGRAVAVKRMLIQFYDIASQETKLLR 797 Query: 528 ESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEK-----KLNFECKIDSVEILRQA 582 ESD H +V+RY+ + F YIALELC A+L D +EK L + D +L Q Sbjct: 798 ESDDHPNVIRYFAQQSAGGFLYIALELCPASLSDVIEKPHLHRDLAQGGEKDLPNVLYQI 857 Query: 583 TMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSF-SRRSGV 641 T G+ HLH++ IVHRD+KP N+L++M S G+ R ++SDFGL KKL + + SF + + Sbjct: 858 TNGIQHLHNLRIVHRDLKPQNILVAM-SKNGKPRLLVSDFGLCKKLEVEQSSFRATTAHA 916 Query: 642 TGTDGWIAPEMI------NGERTTTSID------------------------IFSLGCVF 671 GT GW APE++ G TS D IFSLG VF Sbjct: 917 AGTSGWRAPELLLDDDDKPGSMVDTSTDGGGSGSILVGSDMMHNRRATRAIDIFSLGLVF 976 Query: 672 YYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSAR 729 +YVL+KG HPF GD R+ NI ++NLD L+ IL + K LI +M+ +P +R Sbjct: 977 FYVLTKGSHPFDCGDRYMREVNIRKDNFNLDLLE-ILGDYAFEA-KDLISSMLRKEPKSR 1034 Query: 730 PPCETILKYPMFWCKQSILNFLQDVSD--QVESCACGFGAEHPLERGGARVLRGDWRVRV 787 P ++ +P FW + LNFL DVSD + E A LER V GD+ + Sbjct: 1035 PVAAQVMAHPFFWSAKKRLNFLCDVSDHFEKEKRDPPSPALLELERWAGDVCHGDFLKSL 1094 Query: 788 CRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFP 847 + + +R Y G R+ LLRA+RNKK+HY ++ ++ +G LPDG++S+W +FP Sbjct: 1095 GKEFVDSMGKQRKYTGTRLLDLLRALRNKKNHYEDMPDKLKKDVGPLPDGYLSFWTRKFP 1154 Query: 848 LLLPHVW 854 LL W Sbjct: 1155 NLLIVCW 1161 >UniRef50_Q0UXD0 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 1186 Score = 264 bits (646), Expect = 1e-68 Identities = 165/423 (39%), Positives = 236/423 (55%), Gaps = 50/423 (11%) Query: 475 KIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH 534 +IGK+T D++LG G GTFV+ G +++R+VA+KR+LP+ F A++EV LL+ESD H + Sbjct: 740 RIGKLTIDQDRLLGNGSGGTFVFEGKWNEREVAIKRMLPQYFGLAEQEVKLLQESDLHPN 799 Query: 535 VVRYYCTERDKQFRYIALELCSATLQDY------------VEKKLNFECKIDSVEILRQA 582 V+RY+ E+D+ F YIA+ELC A+L D ++KL+ E + +L Q Sbjct: 800 VIRYFDDEKDENFLYIAVELCQASLFDLYRDGRPGEELTEAQQKLSLEISRNIPRVLYQL 859 Query: 583 TMGLSHLHSMDIVHRDVKPHNVLLSMPS--GTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640 GL+HLHS+ I+HRD+KP N+L++ PS T R +ISDFGL K L + +G Sbjct: 860 AYGLNHLHSLRIIHRDIKPQNILIAYPSRNQTNCPRLVISDFGLCKTLPDNVSTLIGTTG 919 Query: 641 VTGTDGWIAPEMI--------NG-----ERTTTS------------IDIFSLGCVFYYVL 675 GT GW APE+I NG R ++S +DIFSLGCVF+YVL Sbjct: 920 NAGTVGWKAPELISQPKELMNNGSSNGMSRDSSSSTDPVAQGVKRAVDIFSLGCVFFYVL 979 Query: 676 SKGQHPFGD----VLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPP 731 + G HP+ D + R+ NI NL L EE LI+ M+ +P RP Sbjct: 980 TGGCHPYDDDEGWMQIREYNIKKEKANLKQLRLGADSEEPY---HLIQWMLKTRPEDRPT 1036 Query: 732 CETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEH--PLERGGARVL--RGDWRVRV 787 ++ +P FW + LNFL D SD E +EH LE VL + ++ ++ Sbjct: 1037 AVQVMNHPFFWSAEKRLNFLCDCSDHWEREPRDPPSEHLSILEEYSYEVLDSKRNFLAKL 1096 Query: 788 CRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFP 847 L +R Y GDR+ LLRA+RNKK+HY +++ V+ +G LPDG++SYW +FP Sbjct: 1097 DTAFINSLGKQRKYTGDRMLDLLRALRNKKNHYEDMDEIVKAKVGPLPDGYLSYWTIKFP 1156 Query: 848 LLL 850 LL Sbjct: 1157 QLL 1159 Score = 48.0 bits (109), Expect = 0.001 Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 19/168 (11%) Query: 35 FLPDPRH-GFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDG---ILYTGKKSDTWFM 90 ++ +PR G LY P G +L+ L T+ +L AP S D ++Y +K Sbjct: 172 WIVEPREEGALYVLLP-GPYPVLQSLGLTVKQLTDIAPYASDDPELPVVYNVEKRTFMLN 230 Query: 91 IDPLTGFREHVSGFDKSKIF-KSDD------ENTCNSEKKKGIY-VARTEYNILMHDSKN 142 +D TG + F S F SDD +N N +G + + +TEY I++H+ K Sbjct: 231 VDAATGLVKQ--SFSPSGTFGNSDDSCASPVKNVFNERDCRGTFEIGQTEYTIIIHNKKT 288 Query: 143 VNHKWNVTFFDYTSLAMGKDMLNDYGTI----HFTSTSNGRVMSFDRK 186 H + + ++ + + D+ + Y + NG V S+D K Sbjct: 289 NEHVCTIKYAEWAANSRDIDLKSQYTRTMDDQYIYGRFNGEVFSYDHK 336 >UniRef50_A7EHN1 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 1187 Score = 261 bits (639), Expect = 7e-68 Identities = 161/427 (37%), Positives = 232/427 (54%), Gaps = 43/427 (10%) Query: 468 EIGEGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLR 527 E+ +++IG + ++++G G GT V+ G FD R VAVKR+L + + A +E LLR Sbjct: 741 EVSGSKIRIGALEVDQNKLVGMGSNGTMVFEGKFDGRAVAVKRMLIQFYDIASQETKLLR 800 Query: 528 ESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEK-----KLNFECKIDSVEILRQA 582 ESD H +V+RY+ + F YIALELC A+L D +EK L + D +L Q Sbjct: 801 ESDDHPNVIRYFAQQSAAGFLYIALELCPASLADVIEKPHLHRDLAQGGEKDLPNVLYQI 860 Query: 583 TMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSF-SRRSGV 641 G+ HLH++ IVHRD+KP N+L++M G+ R ++SDFGL KKL + + SF + + Sbjct: 861 ANGIQHLHNLRIVHRDLKPQNILVAM-GKNGKPRLLVSDFGLCKKLEVEQSSFRATTAHA 919 Query: 642 TGTDGWIAPEMI------NGERTTTSID------------------------IFSLGCVF 671 GT GW APE++ G TS D IFSLG VF Sbjct: 920 AGTSGWRAPELLLDDDIKQGSMVDTSTDGGGSGSILVSSDMLPNRRATRAIDIFSLGLVF 979 Query: 672 YYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSAR 729 +YVL+KG HPF GD R+ NI ++NL L+ IL + K LI +M+ +P +R Sbjct: 980 FYVLTKGSHPFDCGDRYMREVNIRKDNFNLGLLE-ILGDYAFEA-KDLISSMLCKEPKSR 1037 Query: 730 PPCETILKYPMFWCKQSILNFLQDVSD--QVESCACGFGAEHPLERGGARVLRGDWRVRV 787 P ++ +P FW + LNFL DVSD + E A LER V GD+ + Sbjct: 1038 PVAAQVMAHPFFWSAKKRLNFLCDVSDHFEKEKRDPPSPALLELERWAGDVCHGDFLKPL 1097 Query: 788 CRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFP 847 + + +R Y G R+ LLRA+RNKK+HY ++ ++ +G LPDG++S+W +FP Sbjct: 1098 GKEFVDSMGKQRKYTGTRLLDLLRALRNKKNHYEDMPDKLKKDVGPLPDGYLSFWTRKFP 1157 Query: 848 LLLPHVW 854 LL W Sbjct: 1158 NLLIVCW 1164 >UniRef50_Q4RJK1 Cluster: Chromosome 3 SCAF15037, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 3 SCAF15037, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1113 Score = 250 bits (613), Expect = 1e-64 Identities = 137/281 (48%), Positives = 180/281 (64%), Gaps = 29/281 (10%) Query: 562 YVEKKLNFECK-IDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMIS 620 YVE+K +FE ++ V +L+Q GL+HLHS++IVHRD+KPHN+L+SMP+ G VRAMIS Sbjct: 735 YVERK-DFERHGLEPVMLLQQTMSGLTHLHSLNIVHRDLKPHNILVSMPNAHGRVRAMIS 793 Query: 621 DFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN---GERTTTSIDIFSLGCVFYYVLSK 677 DFGL KKL +GR SFSRRSGV GT+GWIAPE+++ + T ++DIFS GCVFYYV+S+ Sbjct: 794 DFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEVLSEDCKDNPTCAVDIFSAGCVFYYVVSQ 853 Query: 678 GQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILK 737 G HPFG L+RQANIL G Y+LD L + +V + LI M+S +P RP E++LK Sbjct: 854 GSHPFGRSLQRQANILLGTYSLDQLQ--TDKHGDIVARDLIERMLSVEPCKRPSAESVLK 911 Query: 738 YPMFWCKQSILNF----------------------LQDVSDQVESCACGFGAEHPLERGG 775 +P FW + L F LQDVSD++E LERGG Sbjct: 912 HPFFWSLEKELQFFQVSRSFILYFFNFNFTSTVVLLQDVSDRIEKEPLDGSIVRQLERGG 971 Query: 776 ARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNK 816 V++GDWR + + DLR R+Y+G V LLRA+RNK Sbjct: 972 RAVVKGDWREHITVPLQTDLRKFRSYKGGSVRDLLRAMRNK 1012 Score = 154 bits (374), Expect = 1e-35 Identities = 110/341 (32%), Positives = 172/341 (50%), Gaps = 35/341 (10%) Query: 33 PQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGILYTGKKSDTWFMID 92 P FLPDP G LY+ G + + L KLPFTIPELV +PCRS+DG+LY GKK D W+++D Sbjct: 88 PAFLPDPNDGSLYSLGGKNSEG-LTKLPFTIPELVQASPCRSSDGVLYMGKKQDLWYVVD 146 Query: 93 PLTGFREHV--SGF------DKSKIF-----KS----DDENTCN-SEKKKGIYVA-RTEY 133 LTG ++ S F S ++ KS + + C+ +++++ + + EY Sbjct: 147 LLTGEKQQTLTSSFAEMLCPSSSLLYLGRTGKSSTPVNQSSGCDLAQQQRHVCPSVPVEY 206 Query: 134 NILMHDSKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWS 193 I M+D+K+ +WN T+ DY S D Y HF S +G V++ D +GD+ W Sbjct: 207 TITMYDTKSRELRWNATYADYASTLPDDD--TKYKMAHFVSNGDGLVVTVDSDSGDVQWV 264 Query: 194 HNFGTPVVAAYLLDRDGLISVPFNSIGDDTLDHI---MEDAKTLSNGK----GLKNSNIE 246 N+ +PVVA Y+ R+ L V ++ +TL ++ + ++ K K + Sbjct: 265 QNYNSPVVAIYIWQREALRKVAHTNVAVETLRYLTFMSGEVGRITQWKYPFPKEKKPKNK 324 Query: 247 LYPTLYVGEHNHGLYALSSLVDKNTITISTGHQPLLIEGP-STETLKTNAPRYEPIKNIH 305 TLYVG+++ LYA SLV + G ++EGP S ET + P ++ Sbjct: 325 FMATLYVGKYSTSLYASPSLVHDGVTVVPRGSTFPMLEGPDSQETEEDKECVITPSTSVK 384 Query: 306 YKLSDLNLH---VSAPYLLL-GHYKV-PELTTSWIPHLPNS 341 + + H YLLL GH++ PE T + P++ Sbjct: 385 FNAALRKRHRVNFMRNYLLLIGHHETPPEAHTKILERFPDN 425 Score = 137 bits (332), Expect = 1e-30 Identities = 62/97 (63%), Positives = 80/97 (82%), Gaps = 3/97 (3%) Query: 468 EIGEGE---MKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVA 524 E GE E +++G I+F+ +VLG G EGT VY+G FD R VAVKR+LPECF+FADREV Sbjct: 605 EEGEEESSVVRVGNISFRPKEVLGHGAEGTIVYKGQFDNRPVAVKRILPECFSFADREVQ 664 Query: 525 LLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQD 561 LLRESD H +V+RY+CTERD+QF+YIA+ELC+A+LQ+ Sbjct: 665 LLRESDEHPNVIRYFCTERDRQFQYIAIELCAASLQE 701 >UniRef50_Q9FS17 Cluster: OsIre1p; n=4; Oryza sativa|Rep: OsIre1p - Oryza sativa (Rice) Length = 893 Score = 250 bits (612), Expect = 1e-64 Identities = 145/414 (35%), Positives = 220/414 (53%), Gaps = 29/414 (7%) Query: 475 KIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH 534 +IGK+ + ++ GKG GT V+ G++ R+VAVKRLL A +E+ L SD + Sbjct: 486 QIGKLCVYSKEI-GKGSNGTVVFEGSYGGREVAVKRLLRSHNDIASKEIENLIASDQDPN 544 Query: 535 VVRYYCTERDKQFRYIALELCSATLQDYVE----------KKLNFEC-------KIDSVE 577 +VR Y E+D F YI+LE C +L D ++ K + E ++ Sbjct: 545 IVRMYGFEQDNDFVYISLERCRCSLADLIQLHSVPPFSNTKGTDIELWRQDGLPSAQLLK 604 Query: 578 ILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSR 637 ++R G+ HLHS+ I+HRD+KP NVL+S G +RA +SD G+SK+L S S Sbjct: 605 LMRDVVAGIVHLHSLGIIHRDLKPQNVLISKE---GPLRAKLSDMGISKRLQEDMTSVSH 661 Query: 638 RSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY 697 G+ GW APE + R T +ID+FSLGC+ +Y ++KG+HPFG+ R I+ + Sbjct: 662 HGTGFGSSGWQAPEQLRHGRQTRAIDLFSLGCLIFYCITKGKHPFGEYYERDMKIINNQF 721 Query: 698 NLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757 +L +D I PE LI ++ P RP ++ +P FW + L+FL+D SD+ Sbjct: 722 DLFIVDHI-PE-----AVHLISQLLDPDPEKRPTAVYVMHHPFFWSPELCLSFLRDTSDR 775 Query: 758 VESCACGFGAEHPLERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKK 817 +E + LE +W ++ + D+ R Y + LLR IRNK Sbjct: 776 IEKTS-ETDLIDALEGINVEAFGKNWGEKLDAALLADMGRYRKYSFESTRDLLRLIRNKS 834 Query: 818 HHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVWLQMQQY-RDEDILQTYY 870 HYRE D+++ LG LP+GFV Y+ +RFP LL V+ M ++ +DE+ Y+ Sbjct: 835 GHYREFSDDLKELLGSLPEGFVQYFSSRFPKLLIKVYEVMSEHCKDEEAFSKYF 888 >UniRef50_A7PKV5 Cluster: Chromosome chr7 scaffold_20, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr7 scaffold_20, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 741 Score = 231 bits (566), Expect = 5e-59 Identities = 139/401 (34%), Positives = 212/401 (52%), Gaps = 16/401 (3%) Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535 +GK+ F ++ V+ KG GT V G + R VAVKRL+ A +E+ L SD H ++ Sbjct: 348 VGKL-FVSNIVIAKGSNGTIVLEGIHEGRSVAVKRLVRAHHDVAFKEIQNLIASDRHPNI 406 Query: 536 VRYYCTERDKQFRYIALE---LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592 VR+Y E D+ F + + +QD K N + ++R GL HLH + Sbjct: 407 VRWYGVEYDQDFVFTRIPPKTQVKCIVQDIKLWKSNGYPSSVLLSLMRDVVSGLVHLHDL 466 Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652 I+HRD+KP NVL+ + A +SD G+SK+L S + G+ GW APE Sbjct: 467 GIIHRDLKPQNVLIIKEKS---LCAKLSDMGISKRLVGDMSSLGHHATGYGSSGWQAPEQ 523 Query: 653 INGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712 + R T ++D+FSLGC+ + ++ G+HPFGD L R NI+ +L L + +PE Sbjct: 524 LLHGRQTRAVDLFSLGCILFSCITGGRHPFGDPLERDVNIVKNKPDL-FLVEFIPE---- 578 Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQV--ESCACGFGAEHP 770 + + R ++ KP RP +L +P+FW + L+FL+D SD+V E Sbjct: 579 ALDLFAR-LLDPKPELRPKASEVLYHPLFWSSELRLSFLRDASDRVELEDRESNSHVLKA 637 Query: 771 LERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDS 830 LE L G W ++ D+ R Y+ D V LLR IRNK +HYREL ++++ Sbjct: 638 LEGTAPTALGGKWNEKMEPAFLADIGRYRRYKFDSVRDLLRVIRNKWNHYRELPREIQEI 697 Query: 831 LGKLPDGFVSYWLTRFPLLLPHVWLQMQQY-RDEDILQTYY 870 LG +P+GF SY+ +RFP LL V+ + ++ + E+ Q Y+ Sbjct: 698 LGSVPEGFDSYFSSRFPRLLIEVYKVVSRHCKGEECFQKYF 738 Score = 38.3 bits (85), Expect = 1.00 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 5/98 (5%) Query: 58 KLPFTIPELVANAPCRSTDGILYTGKKSDTWFMIDPLTGFREH-VSGFDKSKIFKSDDEN 116 KLP T E +++ P S DG + G K T F+++ TG H + S+ E Sbjct: 54 KLPMTAEEFISSTPHVSEDGGVILGSKQTTVFLLNAKTGKLIHSYRSLESPPTPLSNKEE 113 Query: 117 TCNSEK----KKGIYVARTEYNILMHDSKNVNHKWNVT 150 S + +Y+ RT+Y++ + WN+T Sbjct: 114 NSGSTNLNIVEPRLYITRTDYSLQSFAQGSDKVLWNMT 151 >UniRef50_Q01DV0 Cluster: Endoribonuclease/protein kinase IRE1-like protein; n=2; Ostreococcus|Rep: Endoribonuclease/protein kinase IRE1-like protein - Ostreococcus tauri Length = 971 Score = 229 bits (560), Expect = 3e-58 Identities = 149/405 (36%), Positives = 213/405 (52%), Gaps = 39/405 (9%) Query: 473 EMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAH 532 E +IG++ + VLG G GT V+ G D R VAVKRLL + A +E+ L SD H Sbjct: 483 ETRIGRLLIEPT-VLGYGSCGTIVFAGEMDGRRVAVKRLLAQFHELARKELDALIASDEH 541 Query: 533 AHVVRYYCTERDKQFRYIALELCSATLQDYVE-------------KKLNFECKIDSVEIL 579 +++R + E D+ F Y+ALELC+++L V+ K +N + K + E + Sbjct: 542 PNILRCFALEEDENFVYMALELCASSLAHLVDPVDTGDNVNVLDIKCVNAKTKYPTPECM 601 Query: 580 R---QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGR-VSF 635 R GL+ LH IVHRD+KP NVL++ SG G+ I+D GL+K++NI SF Sbjct: 602 RIMYDVISGLAALHERGIVHRDLKPQNVLITA-SGRGK----IADMGLAKRVNIAEGTSF 656 Query: 636 SRR-------SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRR 688 + V GT GW APE ++ R + S+D+FS GC+ YY L+ G HPFG L+R Sbjct: 657 ETHVAGGPNANSVAGTSGWQAPERLSQGRQSRSVDVFSFGCLMYYALTGGSHPFGSKLQR 716 Query: 689 QANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSIL 748 +N++ ++ L PE + L+R+ I A PS RP + IL +P++W + Sbjct: 717 DSNVMANKSDVSKL-TFFPEAQ-----ALVRSCIDANPSVRPSAKDILSHPIWWDAGKKI 770 Query: 749 NFLQDVSDQV--ESCACGFGAEHPLE-RGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDR 805 FL D SD+V E LE R + DW ++ + ++ R Y G Sbjct: 771 QFLIDASDRVEMEDRVSDRTLLRELEKRAKGAIACEDWTKKLDPALLENMGRYREYNGAS 830 Query: 806 VAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLL 850 V LLR IRNK +HYREL ++ +LG PDG Y RFP LL Sbjct: 831 VRDLLRVIRNKANHYRELPPKLQRALGSYPDGLWQYLSIRFPSLL 875 Score = 65.7 bits (153), Expect = 6e-09 Identities = 51/163 (31%), Positives = 73/163 (44%), Gaps = 15/163 (9%) Query: 42 GFLYTYGP-RGDQQMLKKLPFTIPELVANAPCRSTDGILYTGKKSDTWFMIDPLTGFREH 100 G LY + R + ++++LP T ELV +P + DG L G++S T + ++P TG Sbjct: 132 GALYAHHVGREGKHVVRRLPVTTRELVDASPSATADGALVVGRRSSTIYALNPRTGGVVR 191 Query: 101 VSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHDSKNVNHKWNVTFFDYTSLA-- 158 V D S DE E IYV RTEY + D+ + +WNVT + SL Sbjct: 192 VVNVDGSTTSVDADEVDDEGEL---IYVGRTEYVVRSVDAASGAERWNVTHGELRSLTRD 248 Query: 159 -------MGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSH 194 +G D G+ F V S D +TG W+H Sbjct: 249 SSTGTLKIGTDRAPSSGS--FAIGPGNTVRSVDARTGKTKWTH 289 >UniRef50_UPI000049A534 Cluster: protein kinase; n=1; Entamoeba histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba histolytica HM-1:IMSS Length = 798 Score = 224 bits (548), Expect = 8e-57 Identities = 142/418 (33%), Positives = 223/418 (53%), Gaps = 37/418 (8%) Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535 IG+ + +VLG G GT V+ GT + R VAVKR++ E +TFAD E+ ++ +D H+ Sbjct: 391 IGEQFSCSKKVLGHGSLGTIVFEGTANGRKVAVKRMVKEFYTFADNEMKIINMTDEKPHL 450 Query: 536 VRYYCTERDKQFRYIALELCSATLQDYVEK-------KLNFECKIDS------------V 576 VRYY + D F Y+A+ C TL DY+ K K++ E K ++ V Sbjct: 451 VRYYGSFEDDNFVYLAITFCPYTLDDYLIKIEEIENEKIDEETKENNSSKRLMKLNKERV 510 Query: 577 EILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS 636 ++++ +G+ +LHS+ IVHRD+KP NVL+ G +R I+DFGL+KKL+ SFS Sbjct: 511 RLMKECAIGVYYLHSLGIVHRDIKPLNVLIDENRG---IR--ITDFGLAKKLDPSTSSFS 565 Query: 637 RRSGVTGTDGWIAPEMINGE--RTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILT 694 S G+ GW APEM++ R + ++DIF+LGC+FYY+ ++ +HP+G+ L RQ NIL Sbjct: 566 N-STTKGSIGWQAPEMLDDSCPRLSKAVDIFTLGCLFYYIATR-KHPYGNSLERQNNILK 623 Query: 695 GD-YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQD 753 G + L + E + M P+ R E +L +P+FW + L F+Q Sbjct: 624 GICIKTECSFDNLYQSEFIAC---FNGMNKKNPNERITIEEVLSHPLFWSCKKRLEFIQK 680 Query: 754 VSDQVESCACGFGAEHPLERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAI 813 VSD + + + L+ G + W + ++ + R Y + LLR I Sbjct: 681 VSDIIIADK-NYTISKRLDSAGVAI---QWDKELSPIILQSINKYRIYDFNHTIDLLRVI 736 Query: 814 RNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVWLQMQQ-YRDEDILQTYY 870 RN+ HHY L + +D G PDGF Y+ +FP L ++ +++ Y D+L ++ Sbjct: 737 RNESHHYYTLPQEEKDLYGTFPDGFYKYFHFKFPSLFTVLYSFVKEFYSHSDVLSEFF 794 >UniRef50_UPI0000499C39 Cluster: protein kinase; n=1; Entamoeba histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba histolytica HM-1:IMSS Length = 779 Score = 223 bits (544), Expect = 2e-56 Identities = 139/394 (35%), Positives = 212/394 (53%), Gaps = 23/394 (5%) Query: 483 TDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTE 542 TD+ LG G GT V+ G F+ R VAVKRL+ E ++ A EV + +++ ++VRYY + Sbjct: 398 TDKQLGTGSLGTVVFEGNFNGRRVAVKRLVKEFYSIAQHEVEIFNQTEELPNLVRYYMSY 457 Query: 543 RDKQFRYIALELCSATLQDYV---EKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599 D+ F YIAL C TL+ ++ E + ++ +++ G+ +LH + IVHRD+ Sbjct: 458 SDRNFIYIALTYCECTLEQHINTMEYRKTPLLNEHTIGLMKGCARGVYYLHKLGIVHRDL 517 Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659 KP NVL+ GEV+ I+DFGL+KK+ SF+ G G+ GW APE I GER T Sbjct: 518 KPQNVLI---DSKGEVK--ITDFGLAKKIE-DNASFTCSHG--GSVGWQAPEAIKGERLT 569 Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGD-YNLDHLDKILPEEELVV-IKIL 717 + +DI++LGC+F+++ K +HPFG ++ R NIL G +D+ + + + E V+ + IL Sbjct: 570 SKVDIYNLGCLFFFIARK-EHPFGPLIDRSKNILLGKMVKMDYDNANVYQNEFVMTLAIL 628 Query: 718 IRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLERGGAR 777 R P+ RP + I+ P+FW LNF++ SD E L+ G Sbjct: 629 TR----IDPNLRPTADQIMALPLFWDFNKKLNFIKSASDLFEMDP-SMIITRELDASGIG 683 Query: 778 VLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDG 837 + W+ + + L R Y ++ LLRAIRNK HHY L + PDG Sbjct: 684 I---RWQQSLDPGLVDSLVKFRKYDFNKTRDLLRAIRNKSHHYYNLPKSEQSLFTSFPDG 740 Query: 838 FVSYWLTRFPLLLPHVW-LQMQQYRDEDILQTYY 870 F Y+ RFP LL V+ + + Y +E I ++ Sbjct: 741 FYLYFYKRFPGLLILVYNVVKKHYPNEPIFNEFF 774 >UniRef50_Q55GJ2 Cluster: Putative uncharacterized protein ireA; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein ireA - Dictyostelium discoideum AX4 Length = 984 Score = 213 bits (521), Expect = 1e-53 Identities = 143/432 (33%), Positives = 218/432 (50%), Gaps = 40/432 (9%) Query: 469 IGEGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRE 528 + G +KIGK+ T+++LG G GT VY G + R VAVKR+L + FADREV++L Sbjct: 563 LDNGNVKIGKLEIITNKILGTGSCGTIVYEGKMEGRKVAVKRMLSQFVKFADREVSILIH 622 Query: 529 SDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECK-IDSVEILRQATMG-- 585 SD H +VVRYY E D +F Y+A+ C +L YV++ L+ + DS I G Sbjct: 623 SDEHTNVVRYYAKEEDDEFIYLAISFCQKSLDMYVQQTLSLQISPTDSPSIQSSNNNGNG 682 Query: 586 -LSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAM---------------------ISDFG 623 + ++ + + D K ++L + G + ++ ISD G Sbjct: 683 NNGNNNNNNQIIIDNKTKQMILELFKGLEHLHSLNIVHRDIKPHNVLIDPNNRVKISDMG 742 Query: 624 LSKKLNIGRVSFSRRSGVTGTDGWIAPEMING-ERTTTSIDIFSLGCVFYYVLSKGQHPF 682 L K L+ S + S + GW E +NG R T +DIFSLGCV YY+L+ G HPF Sbjct: 743 LGKLLDNDDQSLTFTS---DSHGWQPAEYLNGTNRNTKKVDIFSLGCVVYYLLT-GAHPF 798 Query: 683 GDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFW 742 G R+ N+L G +++D + K LP+ I L+ +MI +P RP + +P FW Sbjct: 799 GHRYNREKNVLKGKFDIDQI-KHLPD-----IHQLVHSMIQFEPEKRPDIGECINHPFFW 852 Query: 743 CKQSILNFLQDVSD--QVESCACGFGAEHPLERGGARVLRGDWRVRVCRVVAGDLRTRRT 800 L+FL SD + E E GDW +++ +V+ ++ R Sbjct: 853 EVHKKLSFLVAASDYLEFEKPTSPLNLEIDSHVDLVTDGSGDWWLKIDQVLIDNIGRYRK 912 Query: 801 YRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFP--LLLPHVWLQMQ 858 Y G + LLR IRNK +HYR+L + + LG LPDGF +Y+ +FP ++ ++++ Sbjct: 913 YNGKSIRDLLRVIRNKFNHYRDLSPEEQTCLGILPDGFFNYFDLKFPQLFIVTYLFILKN 972 Query: 859 QYRDEDILQTYY 870 D+ +Q YY Sbjct: 973 LKNDQYFVQYYY 984 Score = 35.5 bits (78), Expect = 7.0 Identities = 45/201 (22%), Positives = 83/201 (41%), Gaps = 27/201 (13%) Query: 16 TLSQPVVKVPSQDAN-LMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRS 74 T S P + +P+ D + L+ Q+ D H ++ Q+++ P + EL + S Sbjct: 90 TKSSPSILIPTLDGSGLLFQYSNDRLHQVPFSL-----QELVNTSPLFLKELEDKSSTSS 144 Query: 75 TDGI-----------LYTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENT-CNSEK 122 T ++ G K + ++D TG E + K ++ +D+++ N Sbjct: 145 TSTTSESSKDENKVTMFIGNKKTSITVVDSQTG--EIIKSMSKDGLWLTDEDDCPVNIIP 202 Query: 123 KKGIYVARTEYNILMHDSKNVNHKWNVTFFDY-----TSLAMGKDMLNDYGTIHFTSTSN 177 + + R++Y I+ D K+ KWN++ +Y S + LN G I S S Sbjct: 203 DEALMFTRSDYQIIALDPKSGVEKWNLSVGEYIPHSTKSFYNSEISLNFEGLIEVASLSQ 262 Query: 178 GRVMSFDRKTGDLV--WSHNF 196 + +K V SHN+ Sbjct: 263 RMYKIYIKKPEKTVVGISHNY 283 >UniRef50_Q9FIN6 Cluster: Gb|AAD32909.1; n=5; core eudicotyledons|Rep: Gb|AAD32909.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 939 Score = 202 bits (494), Expect = 3e-50 Identities = 109/303 (35%), Positives = 173/303 (57%), Gaps = 11/303 (3%) Query: 576 VEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSF 635 ++++R GL HLH + IVHRD+KP NVL+ S + A +SD G+SK+L + Sbjct: 646 LKLMRDIVAGLVHLHDIGIVHRDLKPQNVLIVKNSS---LCAKLSDMGISKRLPADTSAL 702 Query: 636 SRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTG 695 +R S +G+ GW APE + ER T ++D+FSLGCV ++ ++ G+HP+GD R N+L Sbjct: 703 TRNSTGSGSSGWQAPEQLRNERQTRAVDLFSLGCVLFFCMTGGKHPYGDNYERDVNVLND 762 Query: 696 DYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVS 755 +L L + LPE L+ +++ P+ RP + ++ +P+FW L+FL+D S Sbjct: 763 QKDL-FLIESLPE-----AVHLLTGLLNPDPNLRPRAQDVMHHPLFWNSDMRLSFLRDAS 816 Query: 756 DQVESCACGFGAE--HPLERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAI 813 D+VE G++ LE A L G W ++ + ++ R Y+ D + LLR I Sbjct: 817 DRVELENREEGSQLLAALESTAAVTLNGRWDEKLDSIFLDNIGRYRRYKFDSIRDLLRVI 876 Query: 814 RNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYYPRT 873 RNK +HYREL ++++ LG +P+GF Y+ +RFP LL V+ + Y + + Y +T Sbjct: 877 RNKLNHYRELPKELQELLGSVPEGFERYFSSRFPKLLIQVYTVLFDYCNNEEFFFKYSKT 936 Query: 874 YVF 876 VF Sbjct: 937 TVF 939 Score = 75.8 bits (178), Expect = 5e-12 Identities = 35/89 (39%), Positives = 59/89 (66%), Gaps = 1/89 (1%) Query: 475 KIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH 534 ++GK+ F +++ + KG GT V G+++ R VAVKRL+ A +E+ L SD H++ Sbjct: 514 RVGKL-FVSNKEIAKGSNGTVVLEGSYEGRLVAVKRLVQSHHDVAQKEILNLMASDKHSN 572 Query: 535 VVRYYCTERDKQFRYIALELCSATLQDYV 563 +VR+Y ++D+ F YI+LELC+ +L D + Sbjct: 573 IVRWYGVDQDEHFIYISLELCACSLNDLI 601 >UniRef50_UPI0000E24A3D Cluster: PREDICTED: endoplasmic reticulum to nucleus signalling 1; n=1; Pan troglodytes|Rep: PREDICTED: endoplasmic reticulum to nucleus signalling 1 - Pan troglodytes Length = 968 Score = 198 bits (483), Expect = 6e-49 Identities = 106/219 (48%), Positives = 138/219 (63%), Gaps = 10/219 (4%) Query: 659 TTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEE-ELVVIKIL 717 T ++DIFS GCVFYYV+S+G HPFG L+RQANIL G +LD L PE+ E V+ + L Sbjct: 737 TYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLH---PEKHEDVIAREL 793 Query: 718 IRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLERGGAR 777 I MI+ P RP + +LK+P FW + L F QDVSD++E + LERGG Sbjct: 794 IEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRA 853 Query: 778 VLRGDWRVRVC-RVVAGD-----LRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSL 831 V++ DWR + + GD LR RTY+G V LLRA+RNKKHHYREL ++VR++L Sbjct: 854 VVKMDWRENITVPLQTGDHAAAYLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETL 913 Query: 832 GKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDEDILQTYY 870 G LPD FV Y+ +RFP LL H + M+ E + Q YY Sbjct: 914 GSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYY 952 Score = 192 bits (468), Expect = 4e-47 Identities = 107/210 (50%), Positives = 135/210 (64%), Gaps = 39/210 (18%) Query: 476 IGKITFQTDQVLGKGCEGTFVYR---------GTFDKRDVAVKRLLPECFTFADREVALL 526 +GKI+F VLG G EGT VYR G FD RDVAVKR+LPECF+FADREV LL Sbjct: 485 VGKISFCPKDVLGHGAEGTIVYRHNSRSSSRRGMFDNRDVAVKRILPECFSFADREVQLL 544 Query: 527 RESDAHAHVVRYYCTERDKQFRYIALELCSATLQD----------------------YVE 564 RESD H +V+RY+CTE+D+QF+YIA+ELC+ATLQ+ YVE Sbjct: 545 RESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEETWTVVLSLFSHGWCGLGGCQLYVE 604 Query: 565 KKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGL 624 +K ++ + +L+Q T GL+HLHS++I R L ++AMISDFGL Sbjct: 605 QKDFAHLGLEPITLLQQTTSGLAHLHSLNIGER--------LHFTRPAARIKAMISDFGL 656 Query: 625 SKKLNIGRVSFSRRSGVTGTDGWIAPEMIN 654 KKL +GR SFSRRSGV GT+GWIAPEM++ Sbjct: 657 CKKLAVGRHSFSRRSGVPGTEGWIAPEMLS 686 Score = 122 bits (295), Expect = 4e-26 Identities = 84/276 (30%), Positives = 141/276 (51%), Gaps = 28/276 (10%) Query: 82 GKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHDSK 141 GKK D W++ID LTG ++ S F ++ C S +Y+ RTEY I M+D+K Sbjct: 2 GKKQDIWYVIDLLTGEKQQTL----SSAFA---DSLCPSTSL--LYLGRTEYTITMYDTK 52 Query: 142 NVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTPVV 201 +WN T+FDY + D+ DY HF S +G V++ D ++GD++W N+ +PVV Sbjct: 53 TRELRWNATYFDYAASLPEDDV--DYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVV 110 Query: 202 AAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLK-------NSNIELYPTLYVG 254 A Y+ R+GL V ++ +TL ++ + + K + +L PTLYVG Sbjct: 111 AFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVG 170 Query: 255 EHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTETLKTNAPRYE----PIKNIHY---- 306 +++ LYA S+V + + G L+EGP T+ + T + E P ++ + Sbjct: 171 KYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGV-TIGDKGECVITPSTDVKFDPGL 229 Query: 307 KLSDLNLHVSAPYLLLGHYKVP-ELTTSWIPHLPNS 341 K + ++ +LL+GH++ P +T + PN+ Sbjct: 230 KSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNN 265 >UniRef50_A7QPE4 Cluster: Chromosome chr18 scaffold_137, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr18 scaffold_137, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 852 Score = 196 bits (478), Expect = 2e-48 Identities = 108/303 (35%), Positives = 168/303 (55%), Gaps = 11/303 (3%) Query: 576 VEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSF 635 ++++R GL+HLH + I+HRD+KP N+L+ + + + A +SD G+SK+L S Sbjct: 558 LKLMRDVVSGLAHLHELGIIHRDLKPQNILIIIKGKS--LSAKLSDMGISKRLLGDMSSL 615 Query: 636 SRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTG 695 + G+ GW APE + R T ++D+FSLGCV ++ L+ G+HP+GD L R NI+ Sbjct: 616 THHGTGYGSSGWQAPEQLRHGRQTRAVDLFSLGCVLFFCLTGGKHPYGDNLERDVNIVNN 675 Query: 696 DYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVS 755 +L ++ I PE L ++ P RP +L +P FW + L+FL+DVS Sbjct: 676 RKDLFLIENI-PE-----AVDLFSLLLEPDPDLRPKAMDVLHHPFFWSSEMRLSFLRDVS 729 Query: 756 DQVESCACGFGAE--HPLERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAI 813 D+VE ++ LE G L G W ++ ++ R Y+ D V LLR I Sbjct: 730 DRVELEDRENESQLLKQLESIGTLALNGKWDEKMEGAFINNIGRYRRYKFDSVRDLLRVI 789 Query: 814 RNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVWLQMQQY-RDEDILQTYYPR 872 RNK +HYREL SD+++ LG +P+GF Y+ +RFP L V+ + + R+E+ Q Y R Sbjct: 790 RNKLNHYRELPSDIQEILGPVPEGFNLYFSSRFPRFLIEVYKVIHTHCREEEFFQKYIQR 849 Query: 873 TYV 875 + Sbjct: 850 NLI 852 Score = 73.3 bits (172), Expect = 3e-11 Identities = 38/98 (38%), Positives = 57/98 (58%), Gaps = 1/98 (1%) Query: 466 LMEIGEGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVAL 525 L ++ GE KIGK+ ++ KG GT V G +D R VAVKRL+ A +E+ Sbjct: 411 LADVHVGERKIGKMLVSKKEI-AKGSNGTIVLEGIYDGRPVAVKRLVRTHHDVALKEIQN 469 Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYV 563 L SD H ++VR++ E D+ F Y++LE C+ +L D + Sbjct: 470 LIASDQHPNIVRWHGVEYDQDFVYLSLERCNCSLSDLI 507 >UniRef50_Q0WPT1 Cluster: Endoribonuclease/protein kinase IRE1; n=3; Arabidopsis thaliana|Rep: Endoribonuclease/protein kinase IRE1 - Arabidopsis thaliana (Mouse-ear cress) Length = 841 Score = 185 bits (450), Expect = 6e-45 Identities = 102/298 (34%), Positives = 168/298 (56%), Gaps = 12/298 (4%) Query: 576 VEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSF 635 ++++R G+ HLH + IVHRD+KP NVL+S + A +SD G+SK+++ S Sbjct: 548 LKLMRDIVCGIVHLHELGIVHRDLKPQNVLISKDM---TLSAKLSDMGISKRMSRDMSSL 604 Query: 636 SRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTG 695 + +G+ GW APE + R T ++D+FSLGCV +Y ++ +HPFGD L R NI+ Sbjct: 605 GHLATGSGSSGWQAPEQLLQGRQTRAVDMFSLGCVIFYTITGCKHPFGDDLERDVNIVKN 664 Query: 696 DYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVS 755 +L L + +PE LI +++ P RP +L +PMFW + L+FL+D S Sbjct: 665 KVDL-FLVEHVPE-----ASDLISRLLNPDPDLRPSATEVLLHPMFWNSEMRLSFLRDAS 718 Query: 756 DQVESCACGFGAE--HPLERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAI 813 D+VE +E +E + G W ++ V ++ R Y+ D + LLR I Sbjct: 719 DRVELENREADSEILKAMESTAPVAIGGKWDEKLEPVFITNIGRYRRYKYDSIRDLLRVI 778 Query: 814 RNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVWLQMQQY-RDEDILQTYY 870 R+K +H+REL ++++ +G +P+GF Y+ RFP LL V+ + + R+E++ + Y+ Sbjct: 779 RSKLNHHRELPPEIQELVGTVPEGFDEYFAVRFPKLLIEVYRVISLHCREEEVFRKYF 836 Score = 76.2 bits (179), Expect = 4e-12 Identities = 37/95 (38%), Positives = 58/95 (61%), Gaps = 1/95 (1%) Query: 475 KIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH 534 KIGK+ F + + + KG GT V+ G ++ R VAVKRL+ A +E+ L SD H + Sbjct: 409 KIGKL-FLSSKEIAKGSNGTVVFEGIYEGRPVAVKRLVRSHHEVAFKEIQNLIASDQHTN 467 Query: 535 VVRYYCTERDKQFRYIALELCSATLQDYVEKKLNF 569 ++R+Y E D+ F Y++LE C+ +L D ++ L F Sbjct: 468 IIRWYGVEYDQDFVYLSLERCTCSLDDLIKSYLEF 502 >UniRef50_Q2UR79 Cluster: Serine/threonine protein kinase and endoribonuclease ERN1/IRE1; n=1; Aspergillus oryzae|Rep: Serine/threonine protein kinase and endoribonuclease ERN1/IRE1 - Aspergillus oryzae Length = 1144 Score = 184 bits (449), Expect = 8e-45 Identities = 97/198 (48%), Positives = 133/198 (67%), Gaps = 11/198 (5%) Query: 466 LMEIGEGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVAL 525 +ME+ +G ++IG++ TD VLG G GT VYRG+FD RDVAVKR+L E + A EV L Sbjct: 693 IMEM-DGVLQIGRLRVFTDVVLGHGSHGTVVYRGSFDGRDVAVKRMLVEFYDIASHEVGL 751 Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFE------CKIDSVEIL 579 L+ESD HA+V+RY+C E+ F YIALELC A+LQD VE+ ++ ++ +IL Sbjct: 752 LQESDDHANVIRYFCREQAAGFLYIALELCPASLQDVVERPSDYPQLVQGGLDVNMPDIL 811 Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMP---SGTGEVRAMISDFGLSKKLNIGRVSF- 635 RQ G+ +LHS+ IVHRD+KP N+L++MP SG +R +ISDFGL KKL + SF Sbjct: 812 RQIICGVRYLHSLKIVHRDLKPQNILVAMPRGRSGARSLRLLISDFGLCKKLEDNQSSFR 871 Query: 636 SRRSGVTGTDGWIAPEMI 653 + + GT GW APE++ Sbjct: 872 ATTAHAAGTSGWRAPELL 889 Score = 142 bits (343), Expect = 5e-32 Identities = 79/200 (39%), Positives = 117/200 (58%), Gaps = 8/200 (4%) Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEELVVI 714 R T +IDIFSLGCVFYYVL++G HPF R+ANI+ G++NLD L+++ + Sbjct: 921 RATRAIDIFSLGCVFYYVLTRGSHPFDKNGKFMREANIVKGNHNLDELERL--GDYAFEA 978 Query: 715 KILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPL--E 772 + LI++M+S P RP ++L +P FW L FL DVSD E +E L E Sbjct: 979 RDLIQSMLSLDPRKRPDASSVLTHPFFWNPSDRLTFLCDVSDHFEFEPRDPPSEALLCLE 1038 Query: 773 RGGARVL--RGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDS 830 +RV+ D+ ++ +L +R Y G ++ LLRA+RNK HHY ++ ++ Sbjct: 1039 SVASRVMGPEMDFLRQLPTSFKDNLGKQRKYTGSKMLDLLRALRNKCHHYNDMPEHLKAH 1098 Query: 831 LGKLPDGFVSYWLTRFPLLL 850 +G LP+G++S+W RFP LL Sbjct: 1099 IGGLPEGYLSFWTVRFPSLL 1118 >UniRef50_Q5BGU5 Cluster: Putative uncharacterized protein; n=2; cellular organisms|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 1100 Score = 180 bits (438), Expect = 2e-43 Identities = 94/191 (49%), Positives = 126/191 (65%), Gaps = 8/191 (4%) Query: 471 EGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESD 530 +G ++IG++ T VLG G GT VYRG+FD RDVAVKR+L E + A EV LL+ESD Sbjct: 676 DGVIQIGRLKVFTADVLGHGSHGTVVYRGSFDGRDVAVKRMLVEFYDIASHEVGLLQESD 735 Query: 531 AHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNF----ECKIDSVEILRQATMGL 586 H +V+RYYC E+ K F YIALELC A+LQD VE+ F +D ++LRQ G+ Sbjct: 736 DHNNVIRYYCREQAKGFFYIALELCPASLQDVVERPDAFPQLVNGGLDMPDVLRQIVAGV 795 Query: 587 SHLHSMDIVHRDVKPHNVLLSMPS---GTGEVRAMISDFGLSKKLNIGRVSF-SRRSGVT 642 +LHS+ IVHRD+KP N+L++ P G+ +R +ISDFGL KKL + SF + + Sbjct: 796 RYLHSLKIVHRDLKPQNILVAAPRGRIGSRAIRLLISDFGLCKKLEDNQSSFRATTAHAA 855 Query: 643 GTDGWIAPEMI 653 GT GW APE++ Sbjct: 856 GTSGWRAPELL 866 Score = 125 bits (301), Expect = 7e-27 Identities = 71/192 (36%), Positives = 109/192 (56%), Gaps = 8/192 (4%) Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEELVVI 714 R T +IDIFSLGCVFYYVL++G HPF R+ANI+ G++NLD L ++ E Sbjct: 898 RATRAIDIFSLGCVFYYVLTRGCHPFDKNGKFMREANIVKGNFNLDELQRL--GEYAFEA 955 Query: 715 KILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSD--QVESCACGFGAEHPLE 772 LIR+M++ P RP +L +P FW L+FL DVSD + E A LE Sbjct: 956 DDLIRSMLALDPRQRPDASAVLTHPFFWNPSDRLSFLCDVSDHFEFEPRDPPSDALLCLE 1015 Query: 773 RGGARVL--RGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDS 830 + V+ D+ + + L +R Y G ++ L+RA+RNK++HY ++ ++ Sbjct: 1016 SVASDVIGPEMDFLKLLPKDFKDSLGKQRKYTGSKMLDLMRALRNKRNHYNDMPEHLKAH 1075 Query: 831 LGKLPDGFVSYW 842 +G LP+G++++W Sbjct: 1076 IGGLPEGYLNFW 1087 >UniRef50_Q759H2 Cluster: ADR293Cp; n=2; Saccharomycetaceae|Rep: ADR293Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 1134 Score = 166 bits (404), Expect = 2e-39 Identities = 87/188 (46%), Positives = 117/188 (62%), Gaps = 14/188 (7%) Query: 483 TDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTE 542 +D++LG G GT V++G+F R VAVKR+L + F A E+ LL SD H +VVRYYC+E Sbjct: 692 SDKILGYGSSGTVVFQGSFQHRPVAVKRMLIDFFDVASHEIKLLAGSDDHPNVVRYYCSE 751 Query: 543 RDKQFRYIALELCSATLQDYVEKK------LNFECKIDSVEILRQATMGLSHLHSMDIVH 596 ++F YIALELC+ATL+D +E K L + +I+ + +L Q G+SHLHSM IVH Sbjct: 752 VTEKFLYIALELCTATLEDVIELKGDSPKFLELQQRINPINVLFQIASGISHLHSMKIVH 811 Query: 597 RDVKPHNVL-------LSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR-SGVTGTDGWI 648 RD+KP N+L L +R +ISDFGL KKL SF + GT GW Sbjct: 812 RDLKPQNILVAPSKAFLHQNQDVSSIRILISDFGLCKKLEAEESSFKTNINNAAGTSGWR 871 Query: 649 APEMINGE 656 APE++NG+ Sbjct: 872 APELLNGK 879 Score = 166 bits (403), Expect = 3e-39 Identities = 89/222 (40%), Positives = 130/222 (58%), Gaps = 5/222 (2%) Query: 653 INGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712 + +R T +IDIFSLGCVFYYVLSKG+HPFGD R+ NIL G+Y+L+ L+K L + V Sbjct: 912 VTKKRLTRAIDIFSLGCVFYYVLSKGKHPFGDRFVREGNILKGEYSLEDLNKTLRDRSTV 971 Query: 713 V-IKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSD--QVESCACGFGAEH 769 + K LI MI P RP +L++P+FW L FL VSD ++E Sbjct: 972 LEAKNLIEQMIQYDPLKRPTAHLLLRHPLFWPVPKKLEFLLKVSDRFEIERRDPPSQLLL 1031 Query: 770 PLERGGARVL-RGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVR 828 LE +V+ DW + +V +L R Y G+++ LLRA+RNK HH+ +L ++ Sbjct: 1032 KLEASSTKVIPNKDWHAKFDQVFMDNLGKYRKYHGEKLMDLLRALRNKYHHFHDLPEELA 1091 Query: 829 DSLGKLPDGFVSYWLTRFPLLLPHVWLQMQ-QYRDEDILQTY 869 + +G +PDGF Y++ RFP LL ++ ++ RD+ IL + Sbjct: 1092 ELMGPIPDGFYYYFIKRFPDLLMEIYYVVKANLRDDQILTEF 1133 >UniRef50_Q557G1 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 1448 Score = 166 bits (403), Expect = 3e-39 Identities = 131/430 (30%), Positives = 219/430 (50%), Gaps = 48/430 (11%) Query: 471 EGEMKIGKITFQTDQ--VLGKGCEGTFVYRGTF-DKRDVAVKRLLPECFTFADREV-ALL 526 E + IGK F ++ +LG+G GT V++G + DK VA+K++ ++EV AL+ Sbjct: 1015 EDFVSIGKFKFNRNESNILGRGSNGTLVFKGLWSDKIPVAIKQMQKAFNPLINKEVEALI 1074 Query: 527 RESDAH-AHVVRYYCTERDKQFRYIALELCSATLQDYVEK-KLN---FECKIDSVEILRQ 581 + + ++++RY E DK Y+ L LC +LQ+ VE KLN +E+ + Sbjct: 1075 SLTSKNCSNMIRYIDKEEDKLHVYLGLTLCDGSLQNLVESGKLNDFVISSNKSIIELAKD 1134 Query: 582 ATMGLSHLHSMDIVHRDVKPHNVLL-----SMPSGTGEVRAMISDFGLSKKLNIGRVSFS 636 G+ LHS DIVH D+ P N+L S + + +ISD GLSK + + S+S Sbjct: 1135 ILFGIQFLHSHDIVHNDLNPRNILTLIGKTSNNNNSSNNSFIISDLGLSK-MEV-ESSYS 1192 Query: 637 RRSGV-TGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFG-DVLRRQANILT 694 S + TG G+ E++ +R T S+DIFSLGC+ +Y+L+ GQHPFG D L R NI++ Sbjct: 1193 FTSNIPTGQGGYHPFEVLQSKRMTKSVDIFSLGCILFYLLTNGQHPFGNDKLFRIVNIIS 1252 Query: 695 GDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDV 754 NL L+ +L LI++MIS S RP + +L +P+FW + + F+ Sbjct: 1253 NKMNLTPLN----SNQLAC--TLIKSMISKDESIRPTIQNVLNHPLFWNLEKKIQFIDAA 1306 Query: 755 SDQV-ESCACGFGAE-----HPLERGGARVLRGDWR--VRVCRVVAGDLRTRRT--YRGD 804 + + E + ++ + + L W + V ++ ++ T Y+ D Sbjct: 1307 LNLIKEPSNSSYNSKLTKQLNHCDDNDEPFLNDSWNHLIDVTNLLTPTKGSKITISYQYD 1366 Query: 805 RVAHLLRAIRNKKHHYRELESDV---------RDSLGKL-----PDGFVSYWLTRFPLLL 850 +V L+R IRN H++E++ + R +L L D + Y+ ++ P L+ Sbjct: 1367 KVRDLIRFIRNTIAHHKEIKRAIIQQFQNQQSRPNLEVLEYLSSQDSILLYFESKIPNLI 1426 Query: 851 PHVWLQMQQY 860 H++ Q++QY Sbjct: 1427 HHIYQQLKQY 1436 >UniRef50_A7TTK3 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 1303 Score = 165 bits (400), Expect = 7e-39 Identities = 87/217 (40%), Positives = 124/217 (57%), Gaps = 14/217 (6%) Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVV-IK 715 R T +IDIFSLGCVFYYVLS GQHPFGD R+ANI+ G+Y+L LD + LV+ K Sbjct: 1085 RLTRAIDIFSLGCVFYYVLSNGQHPFGDRYMREANIIKGNYSLHDLDSTVGNPALVIEAK 1144 Query: 716 ILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHP----- 770 LI M+ P RP +LK+P+FW L FL +SD+ E F P Sbjct: 1145 DLIEKMLDNDPLKRPSASNVLKHPLFWSASKKLQFLLKISDRFE-----FERRDPPSPLL 1199 Query: 771 --LERGGARVL-RGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDV 827 LE ++V+ GDW + + +L R Y G+ + LLR++RNK HHY ++ + Sbjct: 1200 LTLESHASKVIENGDWTSKFNSLFIDNLGRYRKYHGEMLMDLLRSLRNKYHHYNDMPQKL 1259 Query: 828 RDSLGKLPDGFVSYWLTRFPLLLPHVWLQMQQYRDED 864 + +G+LPDGF +Y+L +FP LL +++ + +D Sbjct: 1260 MNEIGQLPDGFYNYFLKKFPNLLIEIYIMASENLSDD 1296 Score = 150 bits (364), Expect = 2e-34 Identities = 83/205 (40%), Positives = 121/205 (59%), Gaps = 30/205 (14%) Query: 483 TDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTE 542 +++VLG G GT VY+G F R VAVKR+L + A RE+ LL ESD H +V+RYYC+E Sbjct: 848 SEKVLGYGSSGTVVYQGEFQGRPVAVKRMLIDFCDIATREIDLLTESDDHPNVIRYYCSE 907 Query: 543 RDKQFRYIALELCSATLQDYVEKKLNFE----------------CKIDSVEILRQATMGL 586 ++F YIALELC++TL+D ++ ++ F ++S+ IL+Q G+ Sbjct: 908 YTEKFLYIALELCNSTLEDLIDTRIKFPDLELSSMNEPPSGPLISDLNSIAILQQIAAGV 967 Query: 587 SHLHSMDIVHRDVKPHNVLLSMPS-------------GTGEVRAMISDFGLSKKLNIGRV 633 +HLH + I+HRD+KP N+L+S T VR +ISDFGL KKL+ + Sbjct: 968 AHLHLLKIIHRDLKPQNILVSTSKKLVEGHTQNQFYINTNNVRILISDFGLCKKLDADKS 1027 Query: 634 SF-SRRSGVTGTDGWIAPEMINGER 657 SF + + GT GW APE+++ R Sbjct: 1028 SFQTNTNNAAGTTGWRAPELLDSNR 1052 Score = 36.3 bits (80), Expect = 4.0 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 21/128 (16%) Query: 54 QMLKKLPFTIPELVANAPCR-STDGIL------------YTGKKSDTWFMIDPLTGFREH 100 Q L KLP +I +L+ ++P T+ I+ YTG + + F ID +TG Sbjct: 281 QGLTKLPISIHQLIMSSPMNLKTNFIIDDIGTIIEEEKTYTGSRQTSMFTIDLITGTVIS 340 Query: 101 VSGF-DKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHDSKNVNHKWNVTFFDYTSLAM 159 GF ++KI+ +D N I + RT Y + +H S + + +NVT+ + ++ Sbjct: 341 AFGFGTENKIYVKEDVIQENL-----IKIGRTTYELEIHSSDSPS--YNVTYTTWQQNSL 393 Query: 160 GKDMLNDY 167 + N+Y Sbjct: 394 DLHLSNNY 401 >UniRef50_Q7Z8F3 Cluster: Serine/threonine kinase IREI; n=2; Sordariomycetes|Rep: Serine/threonine kinase IREI - Trichoderma reesei (Hypocrea jecorina) Length = 1243 Score = 164 bits (399), Expect = 9e-39 Identities = 89/223 (39%), Positives = 128/223 (57%), Gaps = 8/223 (3%) Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEEL 711 NG R T +IDIFSLG VF+YVL+ G HPF GD R+ NI G+YNLD LD + + Sbjct: 1018 NGGRATRAIDIFSLGLVFFYVLTNGSHPFDCGDRYMREVNIRKGNYNLDPLDAL--GDFA 1075 Query: 712 VVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACG--FGAEH 769 K LI +M+ A P ARP ++ +P FW + L FL DVSD +E A Sbjct: 1076 YEAKDLIASMLQASPKARPDSREVMAHPFFWSPKKRLAFLCDVSDSLEKEVRDPPSPALV 1135 Query: 770 PLERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRD 829 LER V++GD+ + R L +R Y G+++ LLRA+RNK++HY ++ ++ Sbjct: 1136 ELERHAPEVIKGDFLKVLTRDFVESLGKQRKYTGNKLLDLLRALRNKRNHYEDMSDSLKR 1195 Query: 830 SLGKLPDGFVSYWLTRFPLLLPHVW--LQMQQYRDEDILQTYY 870 S+G LPDG+++YW +FP+LL W + ++ D + YY Sbjct: 1196 SVGSLPDGYLAYWTVKFPMLLLTCWNVVYNLEWEKTDRFREYY 1238 Score = 159 bits (386), Expect = 3e-37 Identities = 86/186 (46%), Positives = 113/186 (60%), Gaps = 7/186 (3%) Query: 474 MKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHA 533 + +G I TD LG G GT V+ G FD RDVAVKR+ + + A RE LLRESD H Sbjct: 802 ISMGNIEVDTDVELGMGSNGTVVFAGRFDGRDVAVKRMTIQFYDIATRETKLLRESDDHP 861 Query: 534 HVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNF-----ECKIDSVEILRQATMGLSH 588 +V+RYY + F YIALE C+A+L D +EK F + D +L Q T G+SH Sbjct: 862 NVIRYYSQVQRGDFLYIALERCAASLADVIEKPYAFGELAKAGQKDLPGVLYQITNGISH 921 Query: 589 LHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG-VTGTDGW 647 LHS+ IVHRD+KP N+L+++ G R ++SDFGL KKL + SF +G GT GW Sbjct: 922 LHSLRIVHRDLKPQNILVNLDK-DGRPRLLVSDFGLCKKLEDRQSSFGATTGRAAGTSGW 980 Query: 648 IAPEMI 653 APE++ Sbjct: 981 RAPELL 986 >UniRef50_A4QZP3 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 1303 Score = 164 bits (399), Expect = 9e-39 Identities = 87/185 (47%), Positives = 116/185 (62%), Gaps = 7/185 (3%) Query: 475 KIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH 534 K+G + DQ LG G GT V+ G +D RDVAVKR+L + + A +E LLRESD H + Sbjct: 860 KMGSLEVNEDQQLGTGSNGTVVFAGKWDGRDVAVKRMLIQFYDIASQETRLLRESDDHPN 919 Query: 535 VVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFE-----CKIDSVEILRQATMGLSHL 589 V+RYY + F YIALELC A+L + +EK F+ + D +L Q T GLSHL Sbjct: 920 VIRYYAQQSRDAFLYIALELCQASLAEVIEKPAYFKNLAQAGEKDLPNVLYQITNGLSHL 979 Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG-VTGTDGWI 648 HS+ IVHRD+KP N+L++M G+ R ++SDFGL KKL G+ SF + GT GW Sbjct: 980 HSLRIVHRDLKPQNILVNM-GKDGKPRLLVSDFGLCKKLEGGQSSFGATTAHAAGTTGWR 1038 Query: 649 APEMI 653 APE++ Sbjct: 1039 APELL 1043 Score = 140 bits (338), Expect = 2e-31 Identities = 79/227 (34%), Positives = 123/227 (54%), Gaps = 7/227 (3%) Query: 633 VSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQA 690 V S S +G+ + R T +IDIFSLG VF+YVL+KG HP+ GD R+ Sbjct: 1056 VDASMSSAHSGSGSVQGSSDVPNRRATRAIDIFSLGLVFFYVLTKGSHPYDRGDRYMREV 1115 Query: 691 NILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNF 750 NI G ++L L+ + + + + ++ M+S +PS RP ++++P FW + L F Sbjct: 1116 NIRKGSFDLSRLEVL--GDYAMEARDIVERMLSFEPSERPTARDVMRHPFFWSAKKRLAF 1173 Query: 751 LQDVSDQVESCACGFGAE--HPLERGGARVLR-GDWRVRVCRVVAGDLRTRRTYRGDRVA 807 L DVSD E + LE V+ GD+ ++ R L +R Y G R+ Sbjct: 1174 LCDVSDHFEKEPRDPPSWPLQILEEAAPDVITSGDFLRQLPREFVDSLGKQRKYTGSRML 1233 Query: 808 HLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVW 854 LLRA+RNKK+HY ++ ++ ++G LP+G++S+W RF LL + W Sbjct: 1234 DLLRALRNKKNHYEDMPESLKKTVGPLPEGYLSFWTRRFDTLLINCW 1280 >UniRef50_UPI000023E202 Cluster: hypothetical protein FG05775.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG05775.1 - Gibberella zeae PH-1 Length = 1243 Score = 159 bits (385), Expect = 4e-37 Identities = 84/186 (45%), Positives = 115/186 (61%), Gaps = 7/186 (3%) Query: 474 MKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHA 533 +++G I TD+ LG G GT V+ G FD R VAVKR+L + + A +E LLRESD H Sbjct: 806 IRMGNIEVNTDEQLGTGSNGTLVFAGKFDGRAVAVKRMLIQFYDIASQETRLLRESDDHP 865 Query: 534 HVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFE-----CKIDSVEILRQATMGLSH 588 +V+RYY + F YIALE C+A+L D +E+ F + D +L Q T G+SH Sbjct: 866 NVIRYYSQQIRDGFLYIALERCAASLADVIERPHYFRDLANAGRHDLPNVLYQITNGISH 925 Query: 589 LHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG-VTGTDGW 647 LH + IVHRD+KP N+L++ G+ R ++SDFGL KKL G+ SF +G GT GW Sbjct: 926 LHELRIVHRDLKPQNILVN-KGKDGKPRLLVSDFGLCKKLEGGQSSFGATTGRAAGTSGW 984 Query: 648 IAPEMI 653 APE++ Sbjct: 985 RAPELL 990 Score = 147 bits (355), Expect = 2e-33 Identities = 82/216 (37%), Positives = 117/216 (54%), Gaps = 5/216 (2%) Query: 642 TGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNL 699 +G+ +A + R T +IDIFSLG VF+YVL+ G HPF GD R+ NI G YNL Sbjct: 1007 SGSGSVLADDNTTPRRATRAIDIFSLGLVFFYVLTNGSHPFDCGDRYMREVNIRKGQYNL 1066 Query: 700 DHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVE 759 D LD + LI +M+ A P RP + ++ +P FW + L+FL DVSD E Sbjct: 1067 DLLDSLGDFSREA--SDLISSMLEADPKCRPTAKEVMAHPFFWSARKRLSFLCDVSDHFE 1124 Query: 760 SCACGFGAEHPLE-RGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKH 818 + E A + GD+ + R L +R Y G R+ LLRA+RNKK+ Sbjct: 1125 KEPRDPPSSALAELESHASDVTGDFLKALPRDFVDSLGKQRKYNGARLLDLLRALRNKKN 1184 Query: 819 HYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVW 854 HY ++ ++ ++G LPDG++++W RFP LL W Sbjct: 1185 HYEDMPEALKRNVGALPDGYLAFWTVRFPSLLLICW 1220 >UniRef50_Q5KMH4 Cluster: Protein kinase/endoribonuclease, putative; n=1; Filobasidiella neoformans|Rep: Protein kinase/endoribonuclease, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 1073 Score = 158 bits (383), Expect = 8e-37 Identities = 89/240 (37%), Positives = 139/240 (57%), Gaps = 11/240 (4%) Query: 639 SGVTGTDGWIA--PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGD 696 S G+ G IA + + R T ++D+F+LGC++++VL G+HPFG+ R++NI+ G+ Sbjct: 833 SSSVGSSGGIANAEDGVARSRLTKAVDLFALGCLYFWVLLSGEHPFGETYNRESNIVKGE 892 Query: 697 -YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVS 755 N+ L + E E V + L+ ++S++P ARP L +P+FW L FL D S Sbjct: 893 AVNMGMLSLLGEEREEV--EDLVGRLLSSEPDARPSTSECLAHPIFWPAAKRLGFLCDAS 950 Query: 756 DQVESCACGFGAEHPL---ERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRA 812 D+ E AE L E+G V+ DW R+ + G L R Y+G V +LRA Sbjct: 951 DRFEIMQTE-PAEPTLVLLEQGAQSVVGKDWYSRLDKTFTGSLGKYRKYKGGSVRDMLRA 1009 Query: 813 IRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVW--LQMQQYRDEDILQTYY 870 +RNKKHHY++LE V+ LG LP GF+ Y+ +R+P LL HV+ ++ + R+E + + Y+ Sbjct: 1010 MRNKKHHYQDLEPAVQKHLGALPAGFLLYFSSRYPKLLMHVYRTVKESELREESLFEGYF 1069 Score = 153 bits (371), Expect = 2e-35 Identities = 81/178 (45%), Positives = 112/178 (62%), Gaps = 8/178 (4%) Query: 483 TDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTE 542 +D ++G G GT V +GT+ R VAVKRLL + A +EV LL+ SD H +V+RYYC E Sbjct: 648 SDTIIGFGSHGTVVLKGTWGGRPVAVKRLLSDFTRLASQEVKLLQASDDHPNVIRYYCQE 707 Query: 543 RDKQFRYIALELCSATLQDYVE---KKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599 + F YIAL+LC A+L D +E K ++D L + T GL HLH M I+HRD+ Sbjct: 708 KRDNFLYIALDLCQASLADLIESPDKHRELADQLDRKRALMEVTKGLKHLHGMKIIHRDI 767 Query: 600 KPHNVLLSM-PSGTGEVRAMISDFGLSKKLNIGRVSFS-RRSGVTGTDGWIAPEMING 655 KP NVL+S PSG +R ++SDFGL+++L + SF+ + + G+ GW APE I G Sbjct: 768 KPQNVLVSQTPSG---LRILVSDFGLARRLGQDQSSFAPTANNLAGSLGWRAPECIRG 822 Score = 45.6 bits (103), Expect = 0.007 Identities = 31/159 (19%), Positives = 70/159 (44%), Gaps = 10/159 (6%) Query: 34 QFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDG--ILYTGKKSDTWFMI 91 +++ +P G LY + + Q ++KLP ++ +L+ +P + ++TG K + + Sbjct: 92 EYIVEPLSGSLYVHEDKDGQMKMRKLPLSVDQLIELSPFTFPESPTQIFTGSKHTSLMSV 151 Query: 92 DPLTGFR-------EHVSGFDKSKIFKS-DDENTCNSEKKKGIYVARTEYNILMHDSKNV 143 D TG + ++S +D S + DD S ++ +++ RT+Y + +H + Sbjct: 152 DLRTGEQIDCFSPTANLSQYDGSSVCDDLDDLEQRGSSQRDTLFIGRTDYRLTIHSPSSS 211 Query: 144 NHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMS 182 T Y+S + + +T + R ++ Sbjct: 212 QGLSTYTSAAYSSEKKSAPAIQEISYSTYTPNAYNRPLA 250 >UniRef50_Q7S470 Cluster: Putative uncharacterized protein NCU02202.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU02202.1 - Neurospora crassa Length = 1208 Score = 157 bits (381), Expect = 1e-36 Identities = 83/186 (44%), Positives = 114/186 (61%), Gaps = 7/186 (3%) Query: 474 MKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHA 533 +K+G + +Q LG G GT V+ G +D RDVAVKR+L + A +E LLRESD H Sbjct: 760 LKMGSLEVNQEQQLGIGSNGTIVFAGKWDGRDVAVKRMLVQFNEIASQETKLLRESDDHP 819 Query: 534 HVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFE-----CKIDSVEILRQATMGLSH 588 +V+RY+ ++ F YIALELC A+L D +++ F + D +L Q GLSH Sbjct: 820 NVIRYFAQQQSAGFLYIALELCQASLADVIQRPSMFRELAQAGERDMPGVLYQVAKGLSH 879 Query: 589 LHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG-VTGTDGW 647 LHS+ IVHRD+KP N+L++M G R ++SDFGL KKL G+ SF + GT GW Sbjct: 880 LHSLRIVHRDLKPQNILVNM-GKDGRPRILVSDFGLCKKLEGGQSSFGATTAHAAGTTGW 938 Query: 648 IAPEMI 653 APE++ Sbjct: 939 RAPELL 944 Score = 145 bits (352), Expect = 4e-33 Identities = 89/242 (36%), Positives = 130/242 (53%), Gaps = 9/242 (3%) Query: 636 SRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANIL 693 S +GT + +N R T +IDIFSLG VF+YVL+KG HPF GD R++NI Sbjct: 964 SSMHSASGTGSGVVGAGVNVRRVTRAIDIFSLGLVFFYVLTKGHHPFDLGDRYMRESNIR 1023 Query: 694 TGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQD 753 G Y+L L+ + + K LI +M+++ P RP ++ +P FW + LNFL D Sbjct: 1024 KGKYDLQLLEVL--GDYAHDAKDLIESMLNSNPKKRPTAIGVMAHPFFWSPRKRLNFLCD 1081 Query: 754 VSDQVESCACG--FGAEHPLERGGARVL-RGDWRVRVCRVVAGDLRTRRTYRGDRVAHLL 810 VSD E A LE + V+ GD+ + R L +R Y G+R+ LL Sbjct: 1082 VSDHFEKEPRDPPSPALALLEDQSSCVITNGDFLKTLPREFVESLGKQRKYTGNRMLDLL 1141 Query: 811 RAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVW--LQMQQYRDEDILQT 868 RA+RNKK+HY +L +R +G LP+G++ ++ TRFP LL W + + + D + Sbjct: 1142 RALRNKKNHYEDLTPQLRKMVGPLPEGYLGFFTTRFPNLLIKCWEVIADLELEESDRFKE 1201 Query: 869 YY 870 YY Sbjct: 1202 YY 1203 Score = 35.1 bits (77), Expect = 9.3 Identities = 41/183 (22%), Positives = 76/183 (41%), Gaps = 19/183 (10%) Query: 40 RHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGILYTGKKSDTWFMIDPLTGFRE 99 R G +Y + P L K+ T+ +LV +GI+YTG+K ++ TG Sbjct: 224 RDGEIYIWRPSDSGPQLTKMTMTMKQLVETYSGLHMNGIVYTGEKRTNMVTLNAATGAMI 283 Query: 100 HVSGFDKSKIFKSDDE---------NTCNSE--KKKGIYVARTEYNILMHDSKNVNHKWN 148 G I K + E N+ SE ++ I + RTEY + ++ + + + Sbjct: 284 KNLGPRGVNINKVESERCLREYALGNSITSECSNRETITLGRTEYIVGVYRTDG-SPIAS 342 Query: 149 VTFFDYTSLAMGKDMLNDYGTI----HFTSTSNGRVMSF--DRKTGDL-VWSHNFGTPVV 201 + + ++ + D+ + + T +G F DR+ GD ++SH +PV Sbjct: 343 LKYSEWAPNVLDGDLGQQHSATPDKRYITGKPDGTFFGFGLDRENGDRPLFSHQLTSPVA 402 Query: 202 AAY 204 + Sbjct: 403 RVF 405 >UniRef50_Q6BJZ1 Cluster: Similar to CA0532|CaIRE1 Candida albicans CaIRE1 protein kinase; n=1; Debaryomyces hansenii|Rep: Similar to CA0532|CaIRE1 Candida albicans CaIRE1 protein kinase - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 1195 Score = 157 bits (381), Expect = 1e-36 Identities = 84/186 (45%), Positives = 122/186 (65%), Gaps = 15/186 (8%) Query: 483 TDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTE 542 TD++LG G GT VY+GTF+ R VAVKR+L + + A+ EV LL+ESD H +V+RY+C++ Sbjct: 759 TDRILGYGSHGTIVYQGTFENRPVAVKRMLLDFYDIANHEVKLLQESDDHPNVIRYFCSQ 818 Query: 543 --RDKQFRYIALELCSATLQDYVEKKLNFE-----CKIDSVEILRQATMGLSHLHSMDIV 595 ++F YIALELC +L+D +EK +F I++ ++L Q GL +LHS+ IV Sbjct: 819 LSETEKFLYIALELCLCSLEDIIEKSKSFPKDIRLKDINATDVLHQLVSGLHYLHSLKIV 878 Query: 596 HRDVKPHNVLLS--MPSGTGEV----RAMISDFGLSKKLNIGRVSF--SRRSGVTGTDGW 647 HRD+KP N+L++ S T V R +ISDFGL KKL+ + SF + ++ GT GW Sbjct: 879 HRDLKPQNILVADLKKSTTNSVNPSARLLISDFGLCKKLDADQSSFRATTQNAALGTSGW 938 Query: 648 IAPEMI 653 APE++ Sbjct: 939 RAPELL 944 Score = 151 bits (365), Expect = 1e-34 Identities = 83/225 (36%), Positives = 124/225 (55%), Gaps = 4/225 (1%) Query: 649 APEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPE 708 A +NG+R T +IDIFSLGCVF+Y+L+KG HPFGD R+ NI+ G+++L L P Sbjct: 971 ATSNVNGKRLTKAIDIFSLGCVFFYILTKGSHPFGDRYLREGNIIKGEFDLSALKFHCPM 1030 Query: 709 EELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSD--QVESCACGFG 766 + V + LI +MI P RP ILK+P FW L FL VSD ++E Sbjct: 1031 DH-VELSHLIASMIHFNPKMRPGTTAILKHPYFWPINKKLEFLLKVSDRFEIERRDPPSD 1089 Query: 767 AEHPLERGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESD 826 LE V +G+W +L R Y+ +++ LLRA RNK HH+ ++ + Sbjct: 1090 LLLKLESISINVHQGNWHKEFDTEFMDNLGKYRKYQQEKLMDLLRAFRNKYHHFNDMPAT 1149 Query: 827 VRDSLGKLPDGFVSYWLTRFPLLLPHVWLQMQ-QYRDEDILQTYY 870 ++ + LP+GF +Y+ +FP LL V+ ++ +DE I + +Y Sbjct: 1150 LQQKMSPLPNGFYNYFSEKFPSLLMEVYFIVEANLQDEHIFEEFY 1194 Score = 54.8 bits (126), Expect = 1e-05 Identities = 44/187 (23%), Positives = 86/187 (45%), Gaps = 11/187 (5%) Query: 26 SQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCR-STDGILYTGKK 84 S +N++ F+ + G LY + P Q L KLP +I +LV +P S D +YTG + Sbjct: 113 STQSNIL-WFVEPYKDGSLYYFVP---QFGLNKLPTSIKDLVLESPFSLSGDDKIYTGTR 168 Query: 85 SDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHDSKNVN 144 + F I+ TG + V G ++ + + ++ I + +T Y + +H + N Sbjct: 169 KTSLFTINIYTGEIKSVFGNEEKCPNPNTHYRNRDLGQQDTIMLGKTTYELSIHSKEKTN 228 Query: 145 HKWNVTFFDYTSLAMGKDML----NDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTPV 200 WNVT+ + + D++ ++FT + +++ ++ G +W P+ Sbjct: 229 IVWNVTYSQWGPNNIDNDLIVQNQQSMDKLYFTPFHDKSLLAINKDIGTPIWISKL--PL 286 Query: 201 VAAYLLD 207 +A + D Sbjct: 287 LAVNVFD 293 >UniRef50_Q23F24 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 838 Score = 154 bits (374), Expect = 1e-35 Identities = 122/417 (29%), Positives = 192/417 (46%), Gaps = 72/417 (17%) Query: 475 KIGKITFQTDQVLGKGCEGTFVYRGTFDK--------------------RDVAVKRLLPE 514 K + ++VLG G +GT ++ GTF R++AVK+LL + Sbjct: 431 KFKGLQINRNKVLGYGAQGTVIFEGTFQGNIQEQKIVFDLINIVYVNIGREIAVKQLLKD 490 Query: 515 CFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEK--------- 565 A +E+ +L + H ++++YY E K + LE C ++ D ++ Sbjct: 491 NKDLASKEIQMLIKLQ-HKNIIKYYYFEETKDHILLGLEKCVGSISDLIDYANRKNKKKS 549 Query: 566 ----------KLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEV 615 K +F K + GLS+LHS ++HRD+KP N+L+ E+ Sbjct: 550 EQDLKALYNIKTDFFIKSTMKNTFKDCLEGLSYLHSQGVIHRDIKPENILIHYNK---EI 606 Query: 616 RAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVL 675 + ++DFGLSK ++ V F+ GT GW E I+ + T + D+FSLGCVFYY+ Sbjct: 607 K--LADFGLSKNISKTNVIFTND---IGTWGWRPLEQIDNQPLTYNTDVFSLGCVFYYIY 661 Query: 676 SKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETI 735 ++G HPFG+ LR E+E +K LI+ MI S R + Sbjct: 662 TQGGHPFGEYLRM-------------------EDE--TLKDLIQKMIHNDQSKRLTVKEC 700 Query: 736 LKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLER--GGARVLRGD-WRVRVCRVVA 792 LK+P FW +F+ + SD +E+ +E+ VL G+ W V + + Sbjct: 701 LKHPYFWNTLQKFSFICEFSDYIETFDTENKYSDLIEQQAKSLNVLEGNRWDKNVDKSLI 760 Query: 793 GDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLL 849 D + + Y +V L+R IRN+K HY EL +D +G D +Y+ RFP L Sbjct: 761 QDTKVFKFYNYGQVKDLIRLIRNRKSHYHELSESSKDIVGDTLDDMFNYFDERFPKL 817 >UniRef50_Q5A7G9 Cluster: Likely protein kinase/endoribonuclease Ire1; n=2; Candida albicans|Rep: Likely protein kinase/endoribonuclease Ire1 - Candida albicans (Yeast) Length = 1224 Score = 153 bits (370), Expect = 3e-35 Identities = 87/236 (36%), Positives = 131/236 (55%), Gaps = 5/236 (2%) Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYN 698 +G T+G ++ +G+R T +IDIFSLGCVFYY+L+ G HPFGD R+ NI+ G+Y+ Sbjct: 990 NGNGATNGSVSNSATSGKRLTKAIDIFSLGCVFYYILTGGYHPFGDRYLREGNIIKGEYD 1049 Query: 699 LDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSD-- 756 L L + P + I LI +IS PS RP ILK+P+FW L FL VSD Sbjct: 1050 LSLLMEKCPNDRYESID-LISKIISHDPSQRPNTGKILKHPLFWSFSKRLEFLLKVSDRF 1108 Query: 757 QVESCACGFGAEHPLERGGARVLRGDW-RVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRN 815 ++E LE V G+W ++ +L R Y +++ LLRA+RN Sbjct: 1109 EIEKRDPPSPLLLKLEEHAKAVHNGNWHKLLNDDEFMDNLGKYRKYSPEKLMDLLRAMRN 1168 Query: 816 KKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHVWLQMQQ-YRDEDILQTYY 870 K HHY ++ ++ + LPDGF Y+ +FP LL ++ +++ +R+E + + YY Sbjct: 1169 KYHHYNDMPESLQLKMAPLPDGFYKYFNDKFPKLLMEIYYVVEENFRNEHVFKEYY 1224 Score = 152 bits (369), Expect = 4e-35 Identities = 85/192 (44%), Positives = 120/192 (62%), Gaps = 21/192 (10%) Query: 483 TDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTE 542 +D++LG G GT V++GTF+ R VAVKR+L + + A+ EV LL+ESD H +VVRY+C++ Sbjct: 772 SDKILGYGSHGTVVFQGTFENRPVAVKRMLLDFYDIANHEVRLLQESDDHPNVVRYFCSQ 831 Query: 543 --RDKQFRYIALELCSATLQDYVEKKLNFE--CKIDSVEILRQATMGLSHLHSMDIVHRD 598 ++F YIALELC TL+D +EK N C +IL Q T GL +LHS+ IVHRD Sbjct: 832 SSESEKFLYIALELCLCTLEDIIEKPQNMPNLCIPKRNDILYQLTSGLHYLHSLKIVHRD 891 Query: 599 VKPHNVLLSMPSGTGE---------------VRAMISDFGLSKKLNIGRVSF--SRRSGV 641 +KP N+L++ G+ VR +ISDFGL KKL + SF + ++ Sbjct: 892 IKPQNILVANIKKNGKRKNQITEIDETCENNVRLLISDFGLCKKLENDQSSFRATTQNAA 951 Query: 642 TGTDGWIAPEMI 653 +GT GW APE++ Sbjct: 952 SGTSGWRAPELL 963 Score = 54.4 bits (125), Expect = 1e-05 Identities = 47/196 (23%), Positives = 86/196 (43%), Gaps = 15/196 (7%) Query: 17 LSQPVVKVPSQ-----DANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAP 71 + +P+VK+ S A+ + F+ + G LY + P+ L KLP +I +LV +P Sbjct: 105 IDEPLVKIQSNIKDKSAAHNILWFVEPYQDGTLYYFTPKFG---LNKLPTSIKDLVMESP 161 Query: 72 CR-STDGILYTGKKSDTWFMIDPLTG-FREHVSGFDKSKIFKSDDENTCNSEKKKGIYVA 129 S D +YTG + + + I+ TG + D+ I +S I + Sbjct: 162 FTLSGDDKIYTGTRKTSLYNINIHTGEIKSSFGNTDECPIPRSTLPPEAAFNADDTIMIG 221 Query: 130 RTEYNILMHDSKNVNHKWNVTFFDYTSLAMGKDML----NDYGTIHFTSTSNGRVMSFDR 185 +T Y + +H N + WNVT+ + + D++ I+FT + +++ ++ Sbjct: 222 KTTYELSIHSKSNSDVMWNVTYSQWVPNNIDNDLILQNQQSLDKIYFTPFHDRSLLAINK 281 Query: 186 KTGDLVWSHNF-GTPV 200 G +W G PV Sbjct: 282 DIGTPIWISKLPGLPV 297 >UniRef50_A3LWV1 Cluster: Predicted protein; n=2; Pichia|Rep: Predicted protein - Pichia stipitis (Yeast) Length = 1176 Score = 149 bits (361), Expect = 4e-34 Identities = 84/190 (44%), Positives = 122/190 (64%), Gaps = 19/190 (10%) Query: 483 TDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTE 542 +D++LG G GT VY+GTF+ R VAVKR+L + + A+ EV LL+ESD H +V+RY+C++ Sbjct: 728 SDKILGYGSHGTIVYQGTFENRPVAVKRMLLDFYDVANHEVRLLQESDDHPNVIRYFCSQ 787 Query: 543 --RDKQFRYIALELCSATLQDYVEK-KLNFECKIDSV-EILRQATMGLSHLHSMDIVHRD 598 ++F YIALELC +L+D +EK K + + I V ++L Q GL +LHS+ IVHRD Sbjct: 788 SSESEKFLYIALELCLCSLEDIIEKPKKSPQLSIPKVNDVLYQLASGLHYLHSLKIVHRD 847 Query: 599 VKPHNVLL------------SMPS-GTGEVRAMISDFGLSKKLNIGRVSF--SRRSGVTG 643 +KP N+L+ + PS VR +ISDFGL KKL+ + SF + + +G Sbjct: 848 LKPQNILVADIKKTSSSKATTKPSEEENNVRLLISDFGLCKKLDSDQSSFRATTQHAASG 907 Query: 644 TDGWIAPEMI 653 T GW APE++ Sbjct: 908 TSGWRAPELL 917 Score = 141 bits (342), Expect = 7e-32 Identities = 79/219 (36%), Positives = 118/219 (53%), Gaps = 4/219 (1%) Query: 655 GERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVI 714 G+R T +IDIFSLGCV+YY+LS G HPFGD R+ NI+ G+Y++ L + P ++ Sbjct: 959 GKRLTKAIDIFSLGCVYYYILSGGMHPFGDRYLREGNIIKGEYDISLLKQCCPNDKYEAT 1018 Query: 715 KILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSD--QVESCACGFGAEHPLE 772 LI +MI A PS R IL +P+FW + L FL VSD +VE LE Sbjct: 1019 D-LIASMIHANPSKRRSTSKILIHPLFWSSKKRLEFLLKVSDRFEVERRDPPSDLLLKLE 1077 Query: 773 RGGARVLRGDWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLG 832 V G+W + +L R Y +++ LLRAIRNK HH+ ++ ++ + Sbjct: 1078 DRANAVHGGNWHKQFDDEFMDNLGKYRKYHKEKLMDLLRAIRNKYHHFNDMPETLQAQMS 1137 Query: 833 KLPDGFVSYWLTRFPLLLPHVWLQMQQ-YRDEDILQTYY 870 LP GF Y+ +FP LL ++ +++ +E + +Y Sbjct: 1138 PLPGGFYKYFNNKFPNLLMQIYFLIEENLAEEHAFKDFY 1176 Score = 53.6 bits (123), Expect = 2e-05 Identities = 47/199 (23%), Positives = 87/199 (43%), Gaps = 18/199 (9%) Query: 19 QPVVKVPSQDANLMPQ-----FLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCR 73 +P+VK+ S + Q F+ + G LY + P+ L KLP +I +LV +P Sbjct: 103 EPLVKIQSNSSTEDSQSNILWFVEPYQDGSLYYFTPKFG---LNKLPTSIRQLVMESPFS 159 Query: 74 -STDGILYTGKKSDTWFMIDPLTGFREHVSGF---DKSKIFKSDDENTCNSEKKKGIYVA 129 S D +YTG + + ++ TG E VS F +K + + + + I + Sbjct: 160 LSGDDKIYTGSRKTALYTVNIFTG--EIVSSFGNEEKCPVANTHYKIDNLYSRSDTINIG 217 Query: 130 RTEYNILMHDSKNVNHKWNVTFFDYTSLAMGKDML----NDYGTIHFTSTSNGRVMSFDR 185 RT Y + +H N N WNV++ + + D++ ++FT N +++ ++ Sbjct: 218 RTTYELTIHSKLNTNVVWNVSYSQWGPNNIDNDLIMQNSESIDKLYFTPFYNKSILAINK 277 Query: 186 KTGDLVWSHNFGTPVVAAY 204 W N + V+ + Sbjct: 278 DISAPKWLTNLPSFAVSVF 296 >UniRef50_Q55DJ9 Cluster: Putative uncharacterized protein irlD; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein irlD - Dictyostelium discoideum AX4 Length = 1505 Score = 148 bits (359), Expect = 6e-34 Identities = 101/311 (32%), Positives = 164/311 (52%), Gaps = 38/311 (12%) Query: 466 LMEIGEGEMKIGKITF--QTDQVLGKGCEGTFVYRGTFDKR-DVAVKRLLPECFTFADRE 522 ++E+ + ++ IGK F + + ++G+G GT V++G ++ R VA+K++ +E Sbjct: 1037 IIELNKYDISIGKFKFSRKDEFIIGRGSNGTLVFKGIWNDRIPVAIKQMHKAFNPLISKE 1096 Query: 523 V-ALLRESDAHAH-VVRYYCTERDKQFRYIALELCSATLQDYVEKKL------------- 567 + L+ ++ + + +VRY E D F Y+ L LC+ +LQ+ VEK L Sbjct: 1097 IEVLITLTNKNCNNIVRYIDQEEDDMFVYLGLTLCNGSLQNLVEKDLEINLISTSNNENN 1156 Query: 568 ------NF-ECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMIS 620 NF ++ +E+++ G+ LH IVH D+ P N+L+ + R +IS Sbjct: 1157 NNNKLKNFIGSELRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIK------DDRFIIS 1210 Query: 621 DFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQH 680 D GLSK SF+ + TG +G+ E++ +R T S+DIFS+GC+ +Y+++ GQH Sbjct: 1211 DLGLSKMEVTSSYSFTMHAP-TGQEGFHPAEVLLEKRKTKSVDIFSMGCILFYLMTGGQH 1269 Query: 681 PFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPM 740 PFGD R ANILT L+ P + +V LI MIS S RP E IL +P Sbjct: 1270 PFGDKFFRMANILTDKPILE------PLKHNLVACDLISQMISKNESDRPTTENILLHPF 1323 Query: 741 FWCKQSILNFL 751 FW + + F+ Sbjct: 1324 FWNHEKKVKFI 1334 >UniRef50_UPI0000F1E427 Cluster: PREDICTED: similar to SPAC167.01; n=1; Danio rerio|Rep: PREDICTED: similar to SPAC167.01 - Danio rerio Length = 539 Score = 148 bits (358), Expect = 8e-34 Identities = 109/371 (29%), Positives = 182/371 (49%), Gaps = 30/371 (8%) Query: 486 VLGKGCEGTFVYRGTFDK-RDVAVKRLLPECFTFADREVALLRESDAHAH-VVRYYCTER 543 ++ G +GT V+ G D +VAVKR++ + E LR + + +VRY Sbjct: 166 LIANGSDGTQVFLGLRDDGTEVAVKRMVKFNYQVLKNEEEFLRLPELESQSIVRYVDFAE 225 Query: 544 DKQFRYIALELCSATLQDYVEKKL---NFECKIDSVEILRQATMGLSHLHSMD--IVHRD 598 D F Y+ L+LC TL++Y++ L E + +++++ L LH ++HRD Sbjct: 226 DDHFGYLVLQLCEYTLEEYIQDHLPEDKDERTLVLEKLVKEVLCSLQVLHDPQTKVLHRD 285 Query: 599 VKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERT 658 +KP NVL+ + +A ++DFG+S++L G + ++ + GT W A E IN + Sbjct: 286 IKPQNVLIDIQG-----KARLADFGISRRLKQGETTL--QTSIAGTRCWKAKESINKKIN 338 Query: 659 T---TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIK 715 T S DI G + YY+LS G HPFG+ + + NIL G Y+L+HLD L ++ Sbjct: 339 TGYKRSSDIQVAGMLVYYILSGGHHPFGEDVDCEGNILRGRYSLEHLDDDLAKD------ 392 Query: 716 ILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLERGG 775 L+ MI P+ RP E L +P FW + + +L+ + + E+ A L Sbjct: 393 -LVEWMIDGNPNKRPTVEQSLAHPFFWTDERKVRYLKILGSENEA-EKNRKANKELIDAI 450 Query: 776 ARVLRG----DWRVRVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSL 831 ++ G +W+ + + +L +R + + LLR IRN H++ ++ L Sbjct: 451 SKCTEGKSFAEWKSKFPSELVQELEKKRGAYPENMLGLLRFIRNLYGHHK-ADAAKNSPL 509 Query: 832 GKLPDGFVSYW 842 PD FVS + Sbjct: 510 VLFPDLFVSVY 520 >UniRef50_Q55DJ8 Cluster: Putative uncharacterized protein irlC; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein irlC - Dictyostelium discoideum AX4 Length = 1444 Score = 147 bits (355), Expect = 2e-33 Identities = 100/299 (33%), Positives = 157/299 (52%), Gaps = 33/299 (11%) Query: 473 EMKIGKITF--QTDQVLGKGCEGTFVYRGTFDKR-DVAVKRLLPECFTFADREV-ALLRE 528 ++ IGK F + + VLG+G GT V++G ++ R VA+K++ +E+ L+ Sbjct: 971 DISIGKFKFNRKEENVLGRGSNGTLVFKGIWNNRIPVAIKQMQKMFNPLISKEIEVLITL 1030 Query: 529 SDAHAH-VVRYYCTERDKQFRYIALELCSATLQDYVEK-------------KLNFECKID 574 ++ + + +VRY E D+ Y+ L LC +LQ+ VEK +N K + Sbjct: 1031 TNKNCYNIVRYIDQEEDESCVYLGLTLCDGSLQNLVEKGDNNLTLTQFLGYDINSSSKNN 1090 Query: 575 S--VEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGR 632 S +E+++ G+ LH IVH D+ P N+L+ + R +ISD GLSK Sbjct: 1091 SRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIK------DDRFIISDLGLSKMEVTSS 1144 Query: 633 VSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANI 692 SF+ + TG +G+ E++ +R T S+DIFS+GC+ +Y+++ GQHPFGD R NI Sbjct: 1145 YSFTMHAP-TGQEGFHPAEVLLEKRKTKSVDIFSMGCILFYLMTGGQHPFGDKFYRIVNI 1203 Query: 693 LTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFL 751 LT L+ P + +V LI MIS S RP E IL +P FW + + F+ Sbjct: 1204 LTDKPILE------PLKHNLVACDLISQMISKNESDRPTIEKILLHPFFWNHEKKVKFI 1256 >UniRef50_Q54IE8 Cluster: Putative uncharacterized protein irlE; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein irlE - Dictyostelium discoideum AX4 Length = 1350 Score = 144 bits (350), Expect = 8e-33 Identities = 94/296 (31%), Positives = 152/296 (51%), Gaps = 27/296 (9%) Query: 473 EMKIGKITFQTDQ--VLGKGCEGTFVYRGTFDKR-DVAVKRLLPECFTFADREVALLRE- 528 ++ IGK F + +LG+G GT V++G ++ R VA+K++ +E+ +L Sbjct: 893 DVSIGKFKFNKKESNILGRGSNGTLVFKGIWNNRIPVAIKQMQKMFNPLISKEIEILIGL 952 Query: 529 SDAHAHVVRYYCTERDKQFRYIALELCSATLQD-YVEKKLNFECKIDS-----------V 576 ++ + ++V Y E D+ Y+ L LC +LQ Y + KLN ++ + Sbjct: 953 TNKNLNLVGYIDQEEDENCVYLGLTLCDGSLQSLYDQSKLNEFINQNNNQNNNNNNNRVL 1012 Query: 577 EILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS 636 +++ G+ LH +IVH D+ P N+L+ + R +ISD GLSK +FS Sbjct: 1013 DLIIGMINGVIFLHDQNIVHNDLNPRNILVK------DNRLIISDLGLSKMNVSSTYNFS 1066 Query: 637 RRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGD 696 + TG DG+ E++ +R T S+D+FSLGC+ Y++++ G HPFGD R I Sbjct: 1067 TNAIPTGQDGYHPVEVLLEKRKTKSVDVFSLGCLIYFIMTNGAHPFGDKFSRLRYITKSK 1126 Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQ 752 YNL L + +V LI MIS S RP ++LK+P+FW + FL+ Sbjct: 1127 YNLSQLSNL-----NLVATHLIELMISYDESKRPTLSSVLKHPLFWDSLKKIKFLE 1177 >UniRef50_Q86IF7 Cluster: Similar to Arabidopsis thaliana (Mouse-ear cress). Gb|AAD32909.1; n=2; Dictyostelium discoideum|Rep: Similar to Arabidopsis thaliana (Mouse-ear cress). Gb|AAD32909.1 - Dictyostelium discoideum (Slime mold) Length = 1431 Score = 140 bits (340), Expect = 1e-31 Identities = 102/309 (33%), Positives = 156/309 (50%), Gaps = 42/309 (13%) Query: 473 EMKIGKITFQTDQ--VLGKGCEGTFVYRGTFDKR-DVAVKRLLPECFTFADREVALLRE- 528 + +IGK F D+ ++G+G GT V+RG ++ R VAVK++ +E+ +L Sbjct: 977 DFQIGKFKFSRDENNIIGRGSNGTLVFRGIWNDRIPVAVKQMQKAFNPHISKEIEVLIRL 1036 Query: 529 -SDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKK---------------LNFECK 572 S+ ++++RY E D+ F Y+ L LC +LQD +E K F Sbjct: 1037 TSNNCSNMIRYIDQEEDQLFVYLGLTLCEESLQDLMESKRYKEFIEKTTTTNITTTFNNN 1096 Query: 573 IDSVEILRQATM--------GLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGL 624 I + Q + G++ LH DIVH D+ P N+L+ + +ISD GL Sbjct: 1097 IIDENLYEQRILSLFKDVINGINFLHCQDIVHNDLNPRNILVHKGN------FVISDLGL 1150 Query: 625 SKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFG- 683 SK SF+ + TG +G+ E++ +R T S+DIFSLGC+ +Y+L+ GQHPFG Sbjct: 1151 SKMQVETSYSFTNNAP-TGQEGYHPIEVLQEKRKTKSVDIFSLGCILFYLLTNGQHPFGN 1209 Query: 684 DVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWC 743 + L R ANI+ +L+ L P +LV R MIS RP +TIL +P+FW Sbjct: 1210 NKLLRVANIVYDKPDLEPLKFNAPALDLV------RLMISQDEKKRPTIDTILNHPLFWS 1263 Query: 744 KQSILNFLQ 752 + F + Sbjct: 1264 TNEKIKFYE 1272 >UniRef50_Q9SF12 Cluster: Putative uncharacterized protein F26K24.16; n=1; Arabidopsis thaliana|Rep: Putative uncharacterized protein F26K24.16 - Arabidopsis thaliana (Mouse-ear cress) Length = 554 Score = 136 bits (330), Expect = 2e-30 Identities = 88/314 (28%), Positives = 155/314 (49%), Gaps = 28/314 (8%) Query: 576 VEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSF 635 ++++R GL+HLH + +HR++ P NVL+ + T + A ISD LSK L + S+ Sbjct: 249 LKLMRDVVCGLAHLHKLKTIHRNLNPQNVLIIVKDMT--LTAKISDMSLSKHLGGKKSSY 306 Query: 636 SRRSGVTGTDGWIAPEMINGERTTTS---IDIFSLGCVFYYVLSKGQHPFGDVLRRQANI 692 + +G+ GW APE +N ++ D+F+ GC+ +Y + G HPFG R NI Sbjct: 307 KHLATCSGSSGWQAPEQLNKDKKKKEDFPADMFNFGCLLHYAVM-GTHPFGSPSERDTNI 365 Query: 693 LTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQ 752 T N +L + E + LI +++ KP RP +L +P+FW + L FL+ Sbjct: 366 KTN--NKTNLSLVTNLEAIN----LIEQLLNYKPDLRPSATQVLLHPLFWDSEKRLFFLR 419 Query: 753 DVSDQVESCACGFGAEHPLERGGARVLRGDWRVRVCRVVAGDLRT-------------RR 799 + SD++E +G + DW ++ + + R Sbjct: 420 EASDRIELDITMWGDLNKTIAPRVLGESKDWASKLGKTFITHIENLAQAQPGQESRQYNR 479 Query: 800 TYRGDRVAHLLRAIRNKKHHYRELESD--VRDSLGKLPDGFVSYWLTRFPLLLPHVWLQM 857 +Y+ + HLLR IRN H+RE+ D +++ +GK+P+G ++ RFP L+ ++ + Sbjct: 480 SYKYWSLRHLLRLIRNILSHHREILDDPKIKEMVGKVPEGLDIFFTARFPNLMMEIYAFI 539 Query: 858 QQY-RDEDILQTYY 870 + + E+ + Y+ Sbjct: 540 SMHCKGEEAFEKYF 553 Score = 38.3 bits (85), Expect = 1.00 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 3/78 (3%) Query: 490 GCEGTFVYRGTFDKRD-VAVK--RLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQ 546 G G V++G + +R VAVK L F E+ D H++++R++ E+D+ Sbjct: 130 GRNGYEVFQGVYGRRSSVAVKCLDLAHTTEAFIQNEIDNHCLCDDHSNIIRFHGLEQDQS 189 Query: 547 FRYIALELCSATLQDYVE 564 F YI LE +L D ++ Sbjct: 190 FAYICLEPWKCSLDDLIK 207 >UniRef50_UPI0000F21EB0 Cluster: PREDICTED: similar to Endoplasmic reticulum (ER) to nucleus signalling 2; n=1; Danio rerio|Rep: PREDICTED: similar to Endoplasmic reticulum (ER) to nucleus signalling 2 - Danio rerio Length = 581 Score = 133 bits (322), Expect = 2e-29 Identities = 99/299 (33%), Positives = 154/299 (51%), Gaps = 25/299 (8%) Query: 475 KIGKITFQ--TDQVLGKGCEGTFVYRGTF-DKRDVAVKRLL--PECFTFADREVALLRES 529 K+G I F + ++G G G VY G D +VA+KR+ P+ + E+ LR+ Sbjct: 149 KVGSIYFSKSNNYMIGSGGSG-MVYLGLKEDGTEVAIKRICKDPQNSKDFENELKHLRDL 207 Query: 530 DAHA-HVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECK----IDSVEILRQATM 584 + + ++VRY D F Y+AL+LC L +++ K L+ E + D +I++ + Sbjct: 208 NLESKNIVRYVDLAEDDDFYYLALQLCENDLVEHM-KSLDQEVRNNKEFDLRKIVQDVLL 266 Query: 585 GLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVR-AMISDFGLSKKLNIGRVSFSRRSGVTG 643 GL LH ++HRD+KP NVL+ T + A ++DFGLS+KL GR + + G Sbjct: 267 GLQVLHRAGVIHRDIKPKNVLIGNIRSTDSGKNARLADFGLSRKLEEGRSAV--HTARAG 324 Query: 644 TDGWIAPEMINGERTTT---SIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLD 700 T GW A E++N + S DI G + YY+LS G+HPFG + R+ NI G LD Sbjct: 325 TQGWEATEILNQSEKSDYKKSSDIQVAGMLVYYILSDGKHPFGGINDREDNIRKGKCCLD 384 Query: 701 HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVE 759 H+ I V K LI MI+ P+ R + +L +P F + +++ D+ E Sbjct: 385 HIQDI-------VAKDLIEWMINKDPAQRLNIDEVLIHPYFLDEHRKYTIHKELGDRPE 436 >UniRef50_Q86AL1 Cluster: Similar to Dictyostelium discoideum (Slime mold). Adenylyl cyclase; n=2; Dictyostelium discoideum|Rep: Similar to Dictyostelium discoideum (Slime mold). Adenylyl cyclase - Dictyostelium discoideum (Slime mold) Length = 1400 Score = 130 bits (313), Expect = 2e-28 Identities = 104/315 (33%), Positives = 157/315 (49%), Gaps = 41/315 (13%) Query: 471 EGEMKIGKITFQTDQ--VLGKGCEGTFVYRGTF-DKRDVAVKRLLPECFTFADREV-ALL 526 E + IGK F ++ +LG+G GT V++G + DK VA+K++ ++EV AL+ Sbjct: 938 EDFVSIGKFKFNRNESNILGRGSNGTLVFKGIWSDKIPVAIKQMQKAFNPLINKEVEALI 997 Query: 527 RESDAH-AHVVRYYCTERDKQFRYIALELCSATLQDYVEK-KLN--FECKIDSV-EILRQ 581 ++ + ++++RY E DK F Y+ L LC +LQ VE KLN S+ E+ + Sbjct: 998 TLTNKNCSNMIRYIDKEEDKHFVYLGLTLCDVSLQYLVENGKLNEFINSSGKSLNELAKD 1057 Query: 582 ATMGLSHLHSMDIVHRD------------------------VKPHNVLLSMPSGTGEVRA 617 G+ LHS DIVH D +K +N + + Sbjct: 1058 IINGVQFLHSHDIVHNDLNPRNILTLSTNKNNNNNNKSNNKIKSNNNSNNNSNNNSNNSF 1117 Query: 618 MISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSK 677 +ISD GLSK SF+ TG G+ E++ +R T S+DIFSLGC+ +Y+ + Sbjct: 1118 IISDLGLSKMEVESSYSFTTNVP-TGQGGYHPVEVLQSKRMTKSVDIFSLGCILFYLFTN 1176 Query: 678 GQHPFG-DVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETIL 736 GQHPFG D L R NI+ NL+ L L + LI++MIS S RP E +L Sbjct: 1177 GQHPFGNDKLFRIYNIMLNKVNLELLGHNL------LACDLIKSMISNDESKRPTIENVL 1230 Query: 737 KYPMFWCKQSILNFL 751 +P+FW + + F+ Sbjct: 1231 NHPLFWNVEKKIQFI 1245 >UniRef50_A4RRT4 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 1295 Score = 108 bits (259), Expect = 8e-22 Identities = 87/313 (27%), Positives = 152/313 (48%), Gaps = 36/313 (11%) Query: 472 GEMKIGK-ITFQTDQVLGKGCEGTFVYRG-----TFDKRDVAVKRLLP-------ECFTF 518 G ++G+ I + ++V+G G GT+V+RG + + VAVKR+ + Sbjct: 792 GWRRVGESIIYNEEEVIGVGSAGTYVFRGYVRHTSRARHAVAVKRIARPPGEKGRDLVQL 851 Query: 519 ADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEI 578 +REV L+ + V ++C +IA ELC +L++++ ++ N +++ Sbjct: 852 VEREVELMTALNQSPLVPFFHCWGITSSNVFIAQELCPESLREHIARQPNL-LAAKRIKL 910 Query: 579 LRQATMGLSHLHSMD-----IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633 L+ G++ LH I H D+KP N+L++ G+V+ I+D GL +L Sbjct: 911 LKGVAEGIAWLHDDGKTQGCITHNDLKPENLLVT---SNGKVK--IADVGLGVRLRKEEG 965 Query: 634 SFSRRS-------GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD-- 684 + S G++ APE++ + T + DI+++G VF+YVL+ PFG+ Sbjct: 966 DSDQYSLGTFSKYGISIVLAGRAPEILARKPLTPAADIWAMGVVFFYVLTGFNSPFGEDP 1025 Query: 685 -VLRRQANILTGDYNLDHLDKI--LPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741 V IL G YNL L +P + + L+ AM+S P+ RP E +L +P+ Sbjct: 1026 NVKPSDDEILNGRYNLQRLMNANDMPPRRAIEARHLLSAMLSPNPAMRPTAEGVLNHPLL 1085 Query: 742 WCKQSILNFLQDV 754 W ++L L D+ Sbjct: 1086 WDDDTVLENLSDL 1098 >UniRef50_Q4TFM3 Cluster: Chromosome 18 SCAF4374, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 18 SCAF4374, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 262 Score = 104 bits (249), Expect = 1e-20 Identities = 46/94 (48%), Positives = 62/94 (65%), Gaps = 2/94 (2%) Query: 659 TTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILI 718 T ++D+FS GCVFY+V+S+GQHPFGD LRRQ NIL G+Y+L H + E ++ + LI Sbjct: 1 TAAVDVFSAGCVFYFVISRGQHPFGDALRRQVNILAGEYSLLHFKQ--GSHEDIIAQNLI 58 Query: 719 RAMISAKPSARPPCETILKYPMFWCKQSILNFLQ 752 MIS + RP C +LK+P FW + L F Q Sbjct: 59 EQMISTEAETRPSCSCVLKHPFFWSPERQLLFFQ 92 Score = 91.5 bits (217), Expect = 1e-16 Identities = 42/85 (49%), Positives = 58/85 (68%) Query: 787 VCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRF 846 V V DLR RTY+G+ V LLRA+RNKKHHY EL S+V+++LG+LP+GF++Y+ +RF Sbjct: 177 VLPVFLPDLRRFRTYKGNSVRDLLRAMRNKKHHYHELPSEVQETLGELPEGFINYFTSRF 236 Query: 847 PLLLPHVWLQMQQYRDEDILQTYYP 871 P LL H + + E + YYP Sbjct: 237 PRLLMHTYEALLICSHERLFHPYYP 261 >UniRef50_UPI00006CB13C Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 529 Score = 102 bits (244), Expect = 5e-20 Identities = 80/268 (29%), Positives = 134/268 (50%), Gaps = 22/268 (8%) Query: 487 LGKGCEGTF---VYR-GTFDKRD---VAVKRLLPECFT----FADREVALLRESDAHAHV 535 LGKG G+ YR G D+R+ A+K +L + RE+ +L+ D H ++ Sbjct: 42 LGKGSFGSVKLATYRQGQNDRREKKLFAIKTILKDRVKDKIYMLQRELEVLKTLD-HPNI 100 Query: 536 VRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDI 594 +++Y T DK + + +E C L +YV K E + ++ +I+++ ++H+HS +I Sbjct: 101 IKFYETYHDKMYIHFVMEYCPGGDLFEYVANKGPLE-EFEAAQIMKKLFSAVAHIHSKNI 159 Query: 595 VHRDVKPHNVLLSMPSGTG-EVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 VHRD+KP N+L + T +++ I DFGLS++ N + + V GT ++APE+I Sbjct: 160 VHRDLKPENILFTSKDKTSWDIK--IIDFGLSRQFN---SNDKKHMSVVGTPLYVAPEII 214 Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVV 713 + D +SLG + Y +LS G+ PF ++ + D D E Sbjct: 215 GEKNYEKECDNWSLGVIMYILLS-GREPFYAKSLKEVYDKIRNQRYDFNDSCW-ENITKQ 272 Query: 714 IKILIRAMISAKPSARPPCETILKYPMF 741 K LI +++ P R CE LK+ F Sbjct: 273 AKDLISKLLTVDPKKRFTCEQALKHQWF 300 >UniRef50_A0CYE6 Cluster: Chromosome undetermined scaffold_31, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_31, whole genome shotgun sequence - Paramecium tetraurelia Length = 509 Score = 101 bits (242), Expect = 9e-20 Identities = 78/272 (28%), Positives = 135/272 (49%), Gaps = 23/272 (8%) Query: 481 FQTDQVLGKGCEGTF-VYRGTFDKRDVAVKRL----LPECFTFADREVALLRESDAHAHV 535 ++ +VLG G GT V D ++ A+K + + E F RE+ +L + D H ++ Sbjct: 33 YRFGKVLGSGSFGTVKVGYSVRDSKEFAIKTIHKYRMREQFYLVLRELDILTQLD-HPNI 91 Query: 536 VRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 ++ + D + + +E CS L+ VEK + + +S I++Q +++LHSM Sbjct: 92 IKVFEEYEDDMYYHFVMEYCSGGELLERIVEK--GYIGESESKVIMQQLFSAINYLHSMG 149 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 I HRD+KP N+L + ++ + DFGLSKK R + GT ++APE++ Sbjct: 150 IAHRDLKPENILFASKDKDAPIK--VIDFGLSKKFRNINQKLQRMNSKVGTPIYVAPEIL 207 Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFG----DVLRRQANILTGDYNLDHLDKILPEE 709 +G+ + D +SLGC+ +VL G PF D L + D++ D++ E Sbjct: 208 SGD-YSFQCDEWSLGCIM-HVLLCGNPPFQAKQLDKLEVKIKHSEVDFSFTAFDRVSSE- 264 Query: 710 ELVVIKILIRAMISAKPSARPPCETILKYPMF 741 K LI++++ +P R CE L++ F Sbjct: 265 ----AKNLIKSLLVKQPKKRITCEKALEHQWF 292 >UniRef50_UPI0000D9D513 Cluster: PREDICTED: similar to Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (hIRE2p) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2); n=1; Macaca mulatta|Rep: PREDICTED: similar to Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (hIRE2p) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) - Macaca mulatta Length = 323 Score = 100 bits (239), Expect = 2e-19 Identities = 52/118 (44%), Positives = 73/118 (61%), Gaps = 5/118 (4%) Query: 635 FSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILT 694 FS+ + ++ P +++ T+++DIFS GCVFYYVLS G HPFGD L RQANILT Sbjct: 25 FSQADFLEAEISFLRPSLLS---QTSAVDIFSAGCVFYYVLSGGSHPFGDSLYRQANILT 81 Query: 695 GDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQ 752 G L HL++ + ++ VV + L+ AM+S P ARP +L +P FW + L F Q Sbjct: 82 GVPCLAHLEEEVHDK--VVARDLVAAMLSLLPQARPSAPQVLAHPFFWSRAKQLQFFQ 137 Score = 91.1 bits (216), Expect = 1e-16 Identities = 42/86 (48%), Positives = 55/86 (63%) Query: 786 RVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTR 845 R ++ DLR R+Y+G V LLRA+RNKKHHYREL +V+ +LG++PDGFV Y+ R Sbjct: 223 RTLNSLSTDLRKFRSYKGTSVRDLLRAVRNKKHHYRELPVEVQQALGQVPDGFVQYFTNR 282 Query: 846 FPLLLPHVWLQMQQYRDEDILQTYYP 871 FP LL H M+ E + YYP Sbjct: 283 FPQLLLHTHRVMRSCASESLFLPYYP 308 >UniRef50_A0CAC3 Cluster: Chromosome undetermined scaffold_161, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_161, whole genome shotgun sequence - Paramecium tetraurelia Length = 500 Score = 99 bits (238), Expect = 3e-19 Identities = 72/210 (34%), Positives = 112/210 (53%), Gaps = 17/210 (8%) Query: 481 FQTDQVLGKGCEGTFVYRGTFDKR-DVAVKRLLPECFTFADREVALLRESDA-----HAH 534 F+ Q+LGKG T + KR +VA+K + + F ++E A+ +E+ H + Sbjct: 24 FEPRQMLGKGAFATVISAFDKVKRINVAIKIVEKKLFRSKEQEDAIRQEALTLQTLFHKN 83 Query: 535 VVRYYCTERDKQFRYIAL-ELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 +++ +Q YI + ++ TL++Y+ K E I++Q LS+LH D Sbjct: 84 IIQILGFFETQQKFYIVMNQVDGVTLEEYIPKLQMHEV----TPIIKQILRALSYLHQKD 139 Query: 594 IVHRDVKPHNVLLSMPSGTGE-VRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652 IVHRD+KP N+L+ G GE + + DFGLS +N R+ S GT + APE+ Sbjct: 140 IVHRDIKPENILIG---GNGEELSVTLIDFGLSASVN--RIEDGLMSKNCGTLLYQAPEL 194 Query: 653 INGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 I T S+DI++LG V Y +L KG+HPF Sbjct: 195 IKKGNYTRSVDIWALGIVVYNMLYKGEHPF 224 >UniRef50_UPI00006CFA8B Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 579 Score = 99.1 bits (236), Expect = 5e-19 Identities = 71/267 (26%), Positives = 132/267 (49%), Gaps = 21/267 (7%) Query: 485 QVLGKGCEGTFVYRGTFDKRDVAVKRLLP----ECFTFADREVALLRESDAHAHVVRYYC 540 +++GKG G + ++ AVK +L E + RE+ ++++ D H ++V++Y Sbjct: 98 KLIGKGSFGKVRLATNVNGKEFAVKSILKADAGERYYLLRRELDIMKKVD-HPNLVKFYE 156 Query: 541 TERDKQFRYIALELCSAT-LQDYVEKKLNFECKIDSVE---ILRQATMGLSHLHSMDIVH 596 T D ++ +I +E L Y +++ K E I+R+ LSH+H++ I+H Sbjct: 157 TYHDDKYLHIVMEFVQGKELSQYCQERFEVNRKFTESEVAFIVRKLLSALSHMHNLGIIH 216 Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656 RD+K N++++ + I DFGLS+ + + S + + GT ++APE+IN + Sbjct: 217 RDIKLENIMIN----ESNLDVKILDFGLSRDFSQSQASILQ--SIVGTPLYVAPEVINEQ 270 Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEELVVI 714 D +S+G + YY++S G HPF ++ NI + ++N + Sbjct: 271 PYDQKSDSWSMGVLMYYLIS-GSHPFEASNIKELFKNICSANFNFRSSAWSGISKS---A 326 Query: 715 KILIRAMISAKPSARPPCETILKYPMF 741 K+LI ++ P +R CE L+ F Sbjct: 327 KVLITQFLNLDPKSRISCEEALQSDWF 353 >UniRef50_A0C060 Cluster: Chromosome undetermined scaffold_14, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_14, whole genome shotgun sequence - Paramecium tetraurelia Length = 562 Score = 97.9 bits (233), Expect = 1e-18 Identities = 61/195 (31%), Positives = 108/195 (55%), Gaps = 14/195 (7%) Query: 492 EGTF--VYRGTFDKRDVAVK-RLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFR 548 EG+F VY+G F+ ++VAVK +++ F E+++L + D H +++R + Sbjct: 19 EGSFGQVYKGNFNGQEVAVKHQIIQNSFL---SEISILEKID-HPNIIRLLKEYKFGNMS 74 Query: 549 YIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLS 607 Y+ +E CS TL+DY++KKL + + + I+R + +LH I+HRD+KP N+L+ Sbjct: 75 YLVMEYCSGGTLKDYIQKKLTED---EIIGIMRSLLSAVEYLHGQGIIHRDIKPDNILIK 131 Query: 608 MPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSL 667 + ++ ++DFGLS + + + S GT ++APE I ++D +S Sbjct: 132 NKNDLSSIK--LADFGLSFQYDAEIQYYQTVSHQCGTFIFMAPEQILNMSYNKTVDTWSC 189 Query: 668 GCVFYYVLSKGQHPF 682 G V Y +L K +HP+ Sbjct: 190 GIVLYMLLQK-KHPY 203 >UniRef50_UPI000049869A Cluster: receptor protein kinase; n=4; Entamoeba histolytica HM-1:IMSS|Rep: receptor protein kinase - Entamoeba histolytica HM-1:IMSS Length = 1656 Score = 97.1 bits (231), Expect = 2e-18 Identities = 58/195 (29%), Positives = 108/195 (55%), Gaps = 10/195 (5%) Query: 484 DQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYY-CTE 542 D+ LG+G G VY+G + VA+K++ ++E+ +L + + ++R+Y C + Sbjct: 1396 DKFLGEGSFG-MVYKGVYRNITVAIKKMKTNDIDEMEKELEMLNKVKSQC-IIRFYGCVQ 1453 Query: 543 RDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKP 601 + + +EL + D ++KK N + + + A G+ +LH+ I+HRD+KP Sbjct: 1454 TNGNVSLV-MELAEFGSFSDVIQKK-NLKMNL---RVYLDAAKGVEYLHNNGIIHRDIKP 1508 Query: 602 HNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTS 661 NVL+ + ++ ++DFG ++ +NI R + + SG+ GT ++APE++NGE Sbjct: 1509 DNVLIVNNNIDADICGKLTDFGSARMINIIRKNRTFTSGI-GTPIYMAPEILNGEHYEAP 1567 Query: 662 IDIFSLGCVFYYVLS 676 +DIFS+G + Y S Sbjct: 1568 VDIFSMGVMLYEACS 1582 >UniRef50_Q386V5 Cluster: Protein kinase, putative; n=1; Trypanosoma brucei|Rep: Protein kinase, putative - Trypanosoma brucei Length = 751 Score = 96.7 bits (230), Expect = 3e-18 Identities = 80/265 (30%), Positives = 116/265 (43%), Gaps = 15/265 (5%) Query: 481 FQTDQVLGKGCEGTFVYRGTF-DKRDVAVKRL-LPECFTFADREVALLRESDAHAHVVRY 538 F+ + LG G G VY+ D R VAVK++ + DREV +L H H VRY Sbjct: 223 FKIIRELGGGGFGK-VYQAILGDGRFVAVKKMKITSHDKVIDREVRVLSTLPPHKHCVRY 281 Query: 539 YCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRD 598 ++R YI +E S Y+ K + ++ GL H+H DIVHRD Sbjct: 282 LGSKRSSNHYYIFMEYVSGGSIRYIRKSAGVFEEPVMRRCVKMVLEGLQHIHRHDIVHRD 341 Query: 599 VKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERT 658 +K NVLL G V+ I DFG K LN G G GT W++PE+ GE Sbjct: 342 IKGENVLL---DEKGCVK--IVDFGACKVLNSGH----NTVGSVGTPYWMSPEVCRGEAA 392 Query: 659 TTSIDIFSLGCVFYYVLSKGQHP--FGDVLRRQANILTGDYNLDHLDKILPEEELVVIKI 716 T D++ +GC+ + ++ P F +L + KI P+ + Sbjct: 393 TEKSDVWGVGCLCLEMTNESGIPWEFHSTANNTQAVLYSIAAAKNPPKI-PQHLSPAARD 451 Query: 717 LIRAMISAKPSARPPCETILKYPMF 741 I + P RP + +L++P F Sbjct: 452 FIACTLRVDPKDRPTVDKLLQHPFF 476 >UniRef50_Q5KHJ6 Cluster: MAP kinase kinase kinase, putative; n=2; Filobasidiella neoformans|Rep: MAP kinase kinase kinase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 1451 Score = 96.3 bits (229), Expect = 4e-18 Identities = 83/284 (29%), Positives = 142/284 (50%), Gaps = 29/284 (10%) Query: 481 FQTDQVLGKGCEGTFVYRG-------TFDKRDVAVKRLLPECFTFADREVALLRESDAHA 533 +Q +LG+G G VYR T + +++ L P E+ LL+ + HA Sbjct: 9 YQLGDLLGRGASGN-VYRALNFLTGETVAIKSISLLSLPPSSLPDIMSEIDLLKNLN-HA 66 Query: 534 HVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592 ++V+Y RDK+ +I LE C + +LQ ++K F + +V I Q GL +LH Sbjct: 67 NIVKYKGFARDKENLWIILEYCENGSLQTILKKFGKFPESLVAVYI-SQVLEGLIYLHEQ 125 Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG-----VTGTDGW 647 ++HRD+K N+L + G V+ ++DFG+S + + S +S V G+ W Sbjct: 126 GVIHRDIKGANILTNKD---GSVK--LADFGVSSRAPTAVLDQSGKSNDGEAEVVGSPYW 180 Query: 648 IAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQAN-ILTGDYNLDHLDKIL 706 +APE+I +T+ DI+S+GCV +L +G+ P+GD+ QA + D ++ + Sbjct: 181 MAPEVIEQSGASTASDIWSVGCVVVELL-EGKPPYGDLAPMQALWRIVQDESMR-----I 234 Query: 707 PEEELVVIKILIRAMISAKPSARPPCETILKYP-MFWCKQSILN 749 PE ++K + P+ R + +L++P M K+S N Sbjct: 235 PEGASPIVKDFLYHCFQKDPNLRISAKKLLRHPWMLSVKKSASN 278 >UniRef50_A0DUI6 Cluster: Chromosome undetermined scaffold_64, whole genome shotgun sequence; n=3; Oligohymenophorea|Rep: Chromosome undetermined scaffold_64, whole genome shotgun sequence - Paramecium tetraurelia Length = 314 Score = 95.9 bits (228), Expect = 5e-18 Identities = 89/299 (29%), Positives = 149/299 (49%), Gaps = 28/299 (9%) Query: 471 EGEMKIGKITFQTDQVLGKGCEGTF---VYRGT---FDKRDVAVKRLLPECFTFADREVA 524 +G I K+ + ++ LG+G G V + T F + + + L E EV Sbjct: 2 QGNEDINKV-YTLEKTLGEGAFGVVKRAVKKSTGEHFAVKIINKENLSNEDLLALQTEVE 60 Query: 525 LLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQAT 583 +L + D H +VV+ Y D + Y+ LEL + L + + +K +F K ++ LR Sbjct: 61 ILTQID-HPNVVKLYEIYEDDTYFYMVLELMTGGELFERIVEKDHFSEK-EAAATLRPII 118 Query: 584 MGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTG 643 L++ H M IVHRD+KP N+L S ++ +SDFGL++ + V ++ G Sbjct: 119 DALAYCHKMGIVHRDLKPENLLYSTMEPGALLK--VSDFGLARFVGSEEVMMTQ----CG 172 Query: 644 TDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNL-- 699 T G++APE+ING+ T +ID +S+G + Y +L G PF D + + I TG++ Sbjct: 173 TPGYVAPEIINGKGYTEAIDFWSVGVILYIMLC-GFPPFYDEDNDKLFSMIKTGNFAFPS 231 Query: 700 DHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFW--CKQSILNFLQDVSD 756 + D+I E K LI+ +++ P+ R + ILK+P +SI+N + D Sbjct: 232 PYWDQISNE-----AKELIKGLLTIDPAKRLTTDKILKHPWLLNNTHKSIVNLQAKLKD 285 >UniRef50_A6C731 Cluster: Serine/threonine protein kinase; n=1; Planctomyces maris DSM 8797|Rep: Serine/threonine protein kinase - Planctomyces maris DSM 8797 Length = 871 Score = 95.5 bits (227), Expect = 6e-18 Identities = 69/211 (32%), Positives = 111/211 (52%), Gaps = 19/211 (9%) Query: 481 FQTDQVLGKGCEGTFVYRGTFD---KRDVAVKRLLPECFTFADREVALLRESDA-----H 532 ++ V+G+G G V R FD +R VA+K L PE + + LRE+ H Sbjct: 124 YEVLNVVGQGAFG-MVLRA-FDTKLERIVAIKVLAPEMASMSPARKRFLREARTSARIRH 181 Query: 533 AHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHS 591 +VVR + E ++ Y+ +E TLQ +E+ + + + + +Q GL+ H+ Sbjct: 182 ENVVRIHSVE-EEPIPYLVMEFIPGRTLQQQIEEHGPLDLR-SVLRLGKQIAEGLAAAHA 239 Query: 592 MDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPE 651 D++HRD+KP N+LL G E R I+DFGL++ + S ++ + GT ++APE Sbjct: 240 QDLIHRDIKPGNILLE---GDMEERVKITDFGLAR--TVDDASMTQSGMIAGTPMYMAPE 294 Query: 652 MINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 NG+ D+FSLG V Y ++S G+ PF Sbjct: 295 QANGQNLDQRADLFSLGSVLYQMVS-GRPPF 324 >UniRef50_Q9NH60 Cluster: Calcium/calmodulin-dependent protein kinase II isoform B; n=3; Bilateria|Rep: Calcium/calmodulin-dependent protein kinase II isoform B - Caenorhabditis elegans Length = 520 Score = 94.7 bits (225), Expect = 1e-17 Identities = 76/278 (27%), Positives = 135/278 (48%), Gaps = 23/278 (8%) Query: 501 FDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA--T 558 F + + K+L F +RE + R+ H ++VR + + +++ F Y+ +L + Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQ-HPNIVRLHDSIQEESFHYLVFDLVTGGEL 96 Query: 559 LQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAM 618 +D V ++ F + D+ ++Q +++ HS IVHRD+KP N+LL+ + V+ Sbjct: 97 FEDIVARE--FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK-- 152 Query: 619 ISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKG 678 ++DFGL+ ++N G GT G+++PE++ + + +DI++ G V Y+L G Sbjct: 153 LADFGLAIEVN----DSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACG-VILYILLVG 207 Query: 679 QHPF--GDVLRRQANILTG--DYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCET 734 PF D R A I G DY D + PE K LI +M++ P R + Sbjct: 208 YPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPE-----AKSLIDSMLTVNPKKRITADQ 262 Query: 735 ILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLE 772 LK P ++ + + + D V+ C F A L+ Sbjct: 263 ALKVPWICNRERVASAIHR-QDTVD-CLKKFNARRKLK 298 >UniRef50_Q9NH59 Cluster: Calcium/calmodulin-dependent protein kinase II isoform C; n=8; Eumetazoa|Rep: Calcium/calmodulin-dependent protein kinase II isoform C - Caenorhabditis elegans Length = 533 Score = 94.7 bits (225), Expect = 1e-17 Identities = 76/278 (27%), Positives = 135/278 (48%), Gaps = 23/278 (8%) Query: 501 FDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA--T 558 F + + K+L F +RE + R+ H ++VR + + +++ F Y+ +L + Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQ-HPNIVRLHDSIQEESFHYLVFDLVTGGEL 96 Query: 559 LQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAM 618 +D V ++ F + D+ ++Q +++ HS IVHRD+KP N+LL+ + V+ Sbjct: 97 FEDIVARE--FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK-- 152 Query: 619 ISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKG 678 ++DFGL+ ++N G GT G+++PE++ + + +DI++ G V Y+L G Sbjct: 153 LADFGLAIEVN----DSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACG-VILYILLVG 207 Query: 679 QHPF--GDVLRRQANILTG--DYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCET 734 PF D R A I G DY D + PE K LI +M++ P R + Sbjct: 208 YPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPE-----AKSLIDSMLTVNPKKRITADQ 262 Query: 735 ILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLE 772 LK P ++ + + + D V+ C F A L+ Sbjct: 263 ALKVPWICNRERVASAIHR-QDTVD-CLKKFNARRKLK 298 >UniRef50_Q9NH58 Cluster: Calcium/calmodulin-dependent protein kinase II isoform D; n=2; Caenorhabditis elegans|Rep: Calcium/calmodulin-dependent protein kinase II isoform D - Caenorhabditis elegans Length = 571 Score = 94.7 bits (225), Expect = 1e-17 Identities = 76/278 (27%), Positives = 135/278 (48%), Gaps = 23/278 (8%) Query: 501 FDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA--T 558 F + + K+L F +RE + R+ H ++VR + + +++ F Y+ +L + Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQ-HPNIVRLHDSIQEESFHYLVFDLVTGGEL 96 Query: 559 LQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAM 618 +D V ++ F + D+ ++Q +++ HS IVHRD+KP N+LL+ + V+ Sbjct: 97 FEDIVARE--FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK-- 152 Query: 619 ISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKG 678 ++DFGL+ ++N G GT G+++PE++ + + +DI++ G V Y+L G Sbjct: 153 LADFGLAIEVN----DSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACG-VILYILLVG 207 Query: 679 QHPF--GDVLRRQANILTG--DYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCET 734 PF D R A I G DY D + PE K LI +M++ P R + Sbjct: 208 YPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPE-----AKSLIDSMLTVNPKKRITADQ 262 Query: 735 ILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHPLE 772 LK P ++ + + + D V+ C F A L+ Sbjct: 263 ALKVPWICNRERVASAIHR-QDTVD-CLKKFNARRKLK 298 >UniRef50_A2GB48 Cluster: CAMK family protein kinase; n=1; Trichomonas vaginalis G3|Rep: CAMK family protein kinase - Trichomonas vaginalis G3 Length = 400 Score = 94.7 bits (225), Expect = 1e-17 Identities = 72/221 (32%), Positives = 117/221 (52%), Gaps = 21/221 (9%) Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEIL 579 RE+ ++RE D H V++Y D+ YI +E TL D + + E ++ + + Sbjct: 52 REINIMRELD-HPFAVKFYELLEDENRYYIVMEYIEGLTLLDIANRGMISEWRLRHMFV- 109 Query: 580 RQATMGLSHLHS-MDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638 Q T +++LHS +++ HRD+K N++L G +R I DFGLS G Sbjct: 110 -QITCCIAYLHSVLNVAHRDIKLENIILDK---YGNIR--IIDFGLSNSYE-GTGGILNT 162 Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ-ANILTGDY 697 + G+ + APEM GE T + D++SLGCV Y L+ GQ PF + +R AN++ + Sbjct: 163 A--CGSPQYAAPEMFLGEPYTDAADMWSLGCVL-YALATGQLPFDETNQRALANMIVYQH 219 Query: 698 NLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKY 738 ++ D++ P +K LI+A++S PS RP C + K+ Sbjct: 220 P-EYPDEVPPN-----LKNLIQALLSKSPSNRPTCSDVFKF 254 >UniRef50_Q7Z8J5 Cluster: MAP kinase kinase kinase; n=1; Yarrowia lipolytica|Rep: MAP kinase kinase kinase - Yarrowia lipolytica (Candida lipolytica) Length = 944 Score = 94.7 bits (225), Expect = 1e-17 Identities = 67/209 (32%), Positives = 107/209 (51%), Gaps = 12/209 (5%) Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEIL 579 RE+ LLR+ H ++V+Y + D+++ I LE ++ + K FE + + Sbjct: 736 REMNLLRDFQ-HDNIVQYLGSSSDEEYLNIFLEYVPGGSVSSMLTKYGQFEEPLVK-HFV 793 Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639 RQ GL +LHS +I+HRD+K NVL+ G V+ ISDFG+SKK+ S S R Sbjct: 794 RQILKGLDYLHSRNIIHRDIKGANVLV---DNKGNVK--ISDFGISKKI---EASSSNRQ 845 Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNL 699 + G+ W+APE++ T DI+SLGC+ +L+ G HPF + QA G Sbjct: 846 SLQGSVYWMAPEVVKQTSYTLKADIWSLGCLIVEMLT-GSHPFPQFSQMQAIFKIGTSGR 904 Query: 700 DHLDKILPEEELVVIKILIRAMISAKPSA 728 + + E+ +++ + +PSA Sbjct: 905 PDIPENCSEDTKDMLRQTFEQDYNKRPSA 933 >UniRef50_Q8ER22 Cluster: Serine:threonine protein kinase; n=2; Bacillaceae|Rep: Serine:threonine protein kinase - Oceanobacillus iheyensis Length = 688 Score = 93.5 bits (222), Expect = 3e-17 Identities = 61/202 (30%), Positives = 110/202 (54%), Gaps = 17/202 (8%) Query: 488 GKGCEGTFVYRGTFDKRDVAVKRLL------PECFTFADREVALLRESDAHAHVVRYYCT 541 G G ++ R T +RDVAVK L E DRE A S +H ++V + Sbjct: 19 GGGMANVYLARDTILERDVAVKALRMEYIHDQEFIARFDRE-AQSATSLSHPNIVNIFDV 77 Query: 542 ERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVK 600 + Q Y+ +E TL++Y+ + + ++++I++Q T ++H H+ +IVHRD+K Sbjct: 78 GEEDQLLYMVMEYVDGMTLKEYIHQHGPIDVP-EALDIMKQLTSAIAHAHANEIVHRDIK 136 Query: 601 PHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTT 660 P N+L+ + TG+ A ++DFG++ L+ + ++ + + G+ +++PE G T Sbjct: 137 PQNILI---NSTGQ--AKVTDFGIAMALS--ATALTQTNSILGSVHYLSPEQARGGMATK 189 Query: 661 SIDIFSLGCVFYYVLSKGQHPF 682 DI+S+G V Y +L+ G+ PF Sbjct: 190 KSDIYSMGIVLYELLT-GKLPF 210 >UniRef50_Q240Z1 Cluster: Protein kinase domain containing protein; n=3; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 515 Score = 93.5 bits (222), Expect = 3e-17 Identities = 74/276 (26%), Positives = 136/276 (49%), Gaps = 27/276 (9%) Query: 481 FQTDQVLGKGCEGTF---VYRGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----H 532 ++ V+GKG GT + + + +++A+K + + ++ LLRE D H Sbjct: 37 YEFQSVIGKGAFGTVKLACLKNSINDKNIAIKII--DKSMLKQKQYLLLRELDMMKNLDH 94 Query: 533 AHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHS 591 +++++Y +D+ F YI +E C+ L + + KK F K S+ I+ + ++H+HS Sbjct: 95 PNIIKFYEVYQDEMFFYICMEYCAGGELLERITKKKVFSEKEASI-IMEKIFSAINHMHS 153 Query: 592 MDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPE 651 +VHRD+KP N+L S E++ + DFGLS K + S S + GT +++P Sbjct: 154 RGVVHRDIKPENILFSNKYPDSEIK--LIDFGLSTKFD----DNSNLSTMVGTPIYVSPN 207 Query: 652 MINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDHLDKILPEE 709 +++G+ T D +S G V Y+L G PF + + I +G Y +D + + Sbjct: 208 VLDGKYDKT-CDNWSAG-VILYILLVGYPPFFGNNKNEIFKKIKSGSYTMDGFEWANVSQ 265 Query: 710 ELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQ 745 + K L+ ++ R +L++P W K+ Sbjct: 266 ---LAKDLVSKLLVVNSKKRYTAAQVLQHP--WIKK 296 >UniRef50_Q9NYY3 Cluster: Serine/threonine-protein kinase PLK2; n=39; Euteleostomi|Rep: Serine/threonine-protein kinase PLK2 - Homo sapiens (Human) Length = 685 Score = 93.5 bits (222), Expect = 3e-17 Identities = 67/222 (30%), Positives = 106/222 (47%), Gaps = 15/222 (6%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEIL 579 D+E+ L R H HVV++Y DK+ YI LE CS ++ K + + L Sbjct: 128 DKEIELHRILH-HKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 186 Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639 RQ GL +LH +I+HRD+K N ++ + + DFGL+ +L RR Sbjct: 187 RQIVSGLKYLHEQEILHRDLKLGNFFINEA-----MELKVGDFGLAARLEPLE---HRRR 238 Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNL 699 + GT +++PE++N + DI++LGCV Y +L G+ PF N+ + Sbjct: 239 TICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTML-LGRPPF-----ETTNLKETYRCI 292 Query: 700 DHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741 +P L K LI +M+S P RP + I+++ F Sbjct: 293 REARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF 334 >UniRef50_Q2SLI8 Cluster: Serine/threonine protein kinase; n=2; Hahella chejuensis KCTC 2396|Rep: Serine/threonine protein kinase - Hahella chejuensis (strain KCTC 2396) Length = 905 Score = 93.1 bits (221), Expect = 3e-17 Identities = 56/151 (37%), Positives = 85/151 (56%), Gaps = 7/151 (4%) Query: 534 HVVRYYCTERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592 HV+ + T D Y+ +E L L D VEK+ + + V +L Q GL H M Sbjct: 103 HVIDFGNT--DDGMMYLVVEYLRGENLSDLVEKRSGLPLE-NVVWLLEQIGAGLQAAHQM 159 Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652 +IVHRD+KP N++++ SG V A + DFG+SK L G + ++R V GT G++APE Sbjct: 160 NIVHRDLKPGNIIVARVSGDHSV-AKLLDFGISKPLGEGDLKYTRLGMVMGTPGYLAPEQ 218 Query: 653 INGERTTTS-IDIFSLGCVFYYVLSKGQHPF 682 I G R DI++LG + Y+ ++ G+ P+ Sbjct: 219 IEGARNIDKRADIYALGAILYFCIT-GERPY 248 >UniRef50_Q1CYT1 Cluster: Serine/threonine protein kinase; n=2; Cystobacterineae|Rep: Serine/threonine protein kinase - Myxococcus xanthus (strain DK 1622) Length = 389 Score = 93.1 bits (221), Expect = 3e-17 Identities = 76/252 (30%), Positives = 119/252 (47%), Gaps = 18/252 (7%) Query: 487 LGKGCEGTFVYRGTFD--KRDVAVKRLLPECFTFAD-----REVALLRESDAHAHVVRYY 539 LG+G VYRG + +R+VA+K LLP+ + R AL + H ++V Y Sbjct: 48 LGRGGMA-LVYRGLHEMLQREVAIKELLPDGQRDRETLSRFRREALALAAFRHQNIVTLY 106 Query: 540 CTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599 + ++ +EL + K+ + V R A+ L H H I+HRD+ Sbjct: 107 DMVEKGESLFMVMELVDGPTLHTLIKEGPLPADVTGVIAARIAS-ALDHAHFRHIIHRDL 165 Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTT 659 KP NV+L+ +GEV+ M DFG++K ++G + +++ GT +++PE + G Sbjct: 166 KPANVMLTK---SGEVKLM--DFGIAK--DVGMEALTQQGMAVGTPSYMSPEQVTGVPVD 218 Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719 DIFSLG + Y LS G PF + D L K+ P +++I+ R Sbjct: 219 GRTDIFSLGVLLYEALS-GARPFHGKTAGEVFAKIRDGKYTPLSKVAPNVPAPLVRIIQR 277 Query: 720 AMISAKPSARPP 731 AM KP R P Sbjct: 278 AM-EVKPEDRFP 288 >UniRef50_Q5XTZ4 Cluster: Salt-inducible protein kinase; n=2; Poaceae|Rep: Salt-inducible protein kinase - Zea mays (Maize) Length = 323 Score = 93.1 bits (221), Expect = 3e-17 Identities = 68/214 (31%), Positives = 114/214 (53%), Gaps = 22/214 (10%) Query: 487 LGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALL-----RESDA-----HAHVV 536 LG G GT VY G + DVA+KR+ CFT E+ L RE++ H +VV Sbjct: 52 LGSGAFGT-VYHGKWRGSDVAIKRIKKSCFTGRSSELERLAHEFWREAEILSKLHHPNVV 110 Query: 537 RYYCTERDKQFRYIALE---LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 +Y +D +A + + +L+ +++K + + + I A GL +LHS + Sbjct: 111 AFYGVVKDGPGGTLATVTEFMVNGSLRHVLQRKDKYLDRRKRLIIAMDAAFGLEYLHSKN 170 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 IVH D+K N+L+++ + + + DFGLSK I R + + GV GT W+APE++ Sbjct: 171 IVHVDLKCDNLLVNLKDQSRPI-CKVGDFGLSK---IKRNTLA-SGGVRGTLPWMAPELL 225 Query: 654 NG--ERTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685 NG + + +D+FS G V + +L+ G+ P+ ++ Sbjct: 226 NGSSNKVSEKVDVFSFGIVMWEILT-GEEPYANM 258 >UniRef50_A0C5Z9 Cluster: Chromosome undetermined scaffold_151, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_151, whole genome shotgun sequence - Paramecium tetraurelia Length = 510 Score = 93.1 bits (221), Expect = 3e-17 Identities = 67/205 (32%), Positives = 111/205 (54%), Gaps = 14/205 (6%) Query: 485 QVLGKGCEGTFV-YRGTFDKRDVAVKRLLPECFTFADREV----ALLRESDAHAHVVRYY 539 ++LGKG T + + + A+K + F +V A L H ++VR Sbjct: 27 RILGKGAFSTVIEIQNLMTNKKAALKIIEKSNFNTLQLDVLRKEAQLLNQLNHQNIVRVT 86 Query: 540 CTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRD 598 ++ K +I ++L + TL+ + KL+ + + V+ L QA + +LHS DI+HRD Sbjct: 87 FSKETKSKLFIMMDLITGVTLEQFQLNKLDDQTVHNIVKQLLQA---IKYLHSKDIIHRD 143 Query: 599 VKPHNVLLSMPSGTGE-VRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGER 657 +KP N+++S TGE VR + DFGLS +L S S GT ++APEMI ++ Sbjct: 144 IKPENIMISQ---TGEDVRVTLIDFGLSAQLTYLEGS-GIMSDNCGTFLYMAPEMIQKKK 199 Query: 658 TTTSIDIFSLGCVFYYVLSKGQHPF 682 S+DI+++G V + +L++G+HPF Sbjct: 200 YNRSVDIWAMGIVVFNLLTQGKHPF 224 >UniRef50_A5DK85 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 762 Score = 93.1 bits (221), Expect = 3e-17 Identities = 70/241 (29%), Positives = 118/241 (48%), Gaps = 19/241 (7%) Query: 504 RDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDY 562 ++ +V++L E++LL+ + H ++VRY + D+ + I LE ++Q Sbjct: 522 KNSSVEKLQQSLIEALQHEMSLLKVLN-HENIVRYLGSSTDENYLNIFLEYVPGGSVQSM 580 Query: 563 VEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDF 622 + FE + +RQ +GLS+LH DI+HRD+K N+L+ + GT ISDF Sbjct: 581 LNSYGPFEEPLIR-NFIRQILIGLSYLHGEDIIHRDIKGANILIDI-KGT----VKISDF 634 Query: 623 GLSKKLNIGRVSFS------RRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLS 676 G+SKK + + RR+ + G+ W+APE++ T DI+S+GC+ + + Sbjct: 635 GISKKESSNELESQTQLRSRRRASLQGSVFWMAPEVVKQTAYTKKADIWSVGCLIVEMFT 694 Query: 677 KGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETIL 736 G+HPF D+ + QA G H+ +PE K + S RP +L Sbjct: 695 -GKHPFPDLSQMQAIFKIG----THIKPQIPEWCTAEAKDFLTKTFETDHSLRPDAVDLL 749 Query: 737 K 737 + Sbjct: 750 E 750 >UniRef50_A2DY61 Cluster: CAMK family protein kinase; n=1; Trichomonas vaginalis G3|Rep: CAMK family protein kinase - Trichomonas vaginalis G3 Length = 421 Score = 92.7 bits (220), Expect = 4e-17 Identities = 77/267 (28%), Positives = 128/267 (47%), Gaps = 23/267 (8%) Query: 481 FQTDQVLGKGCEGTFVY-RGTFDKRDVAVKRLLPECFTFADREVAL----LRESDAHAHV 535 +Q Q +G G G V + A+K++ T R+ AL L H ++ Sbjct: 6 YQVIQTIGTGSYGKVVLAKEKKSGTKYAIKKVKLSGMTVEQRQKALEEVNLLLKLNHPNI 65 Query: 536 VRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDI 594 VR Y + K +I ++ L + +EK + ++D + Q + LS++H +I Sbjct: 66 VRCYKSFIKKCTLHIVMDYVDGGNLDNVIEKTHEYMSEMDVLSFFIQIVIALSYIHKKNI 125 Query: 595 VHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN 654 +HRD+KP NV L M +G A + DFG+SK L S + V GT ++APE+ + Sbjct: 126 IHRDIKPENVFL-MKNGI----AKLGDFGISKTL---ESSIGLATTVIGTPYYLAPEVWS 177 Query: 655 GERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQA--NILTGDYNLDHLDKILPEEELV 712 GE+ T D++SLGC+ Y + + + PF +++ IL G + K +P Sbjct: 178 GEQYNTKADMWSLGCILYEMCAL-EKPFTGENQKELFDKILAGHH------KEIPSMYSN 230 Query: 713 VIKILIRAMISAKPSARPPCETILKYP 739 ++ L+ ++S PS RP IL+ P Sbjct: 231 DLRHLVDGLLSMDPSFRPTSAQILQLP 257 >UniRef50_A0BF29 Cluster: Chromosome undetermined scaffold_103, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_103, whole genome shotgun sequence - Paramecium tetraurelia Length = 575 Score = 92.7 bits (220), Expect = 4e-17 Identities = 75/281 (26%), Positives = 141/281 (50%), Gaps = 22/281 (7%) Query: 473 EMKIGKITFQTDQVLGKGCEGTFVYR---GTFDKRDVAVKRLLPECFTF-ADREVALLR- 527 ++K+G TD++LGKG G VY T +D+ VK + + T A +E+ LL+ Sbjct: 4 KIKVGHYNINTDEMLGKGSFG-IVYSCQSDTLKNKDLCVKIISCKNATVQAHKEIQLLQL 62 Query: 528 -ESDAHAHVVRYYCTERDKQFRYIALELC-----SATLQDYVEKKLNFECKIDSVEILRQ 581 + + +++ Y +D+ Y+ ++ C + +QDY KK F + +++ Q Sbjct: 63 LQRVTNPNLITIYDVIQDQNQIYVFMDRCRGGDLKSLIQDYNLKKKQFTLE-QIADMVSQ 121 Query: 582 ATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGV 641 G L ++HRD+KP N+L + ++ ++DFGLSK L+ +S + Sbjct: 122 IVCGYEALIQNKMIHRDLKPANILFEFKTKE-KITLKLTDFGLSKVLD--DISIKQYMTR 178 Query: 642 TGTDGWIAPEMINGERTTTSIDIFSLGCVFY-----YVLSKGQHPFGDVLRRQANILTGD 696 GT +++P++ G++ + DIFSLG + Y + S+G +P L Q ++ T Sbjct: 179 VGTPAYMSPQIALGDKFSAKCDIFSLGIIIYELTFLEIPSQGMNPLIRNL-FQKSLKTKP 237 Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILK 737 + +L++ P + +I+ LI M+S + RP + ++K Sbjct: 238 FVCPNLNQQQPAQLKCLIQDLINKMLSFEEEKRPSWDQLIK 278 >UniRef50_Q556S2 Cluster: Putative uncharacterized protein; n=2; Dictyostelium discoideum|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 513 Score = 92.3 bits (219), Expect = 6e-17 Identities = 68/225 (30%), Positives = 124/225 (55%), Gaps = 18/225 (8%) Query: 477 GKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFAD-----REVALLRESDA 531 G+ +F+ + LG+G G+ VYR + ++ E F D +E+ +L++ + Sbjct: 38 GETSFEIQEKLGEGSFGS-VYRAIHKSSNTSIAIKEFEIFEANDVEPISKEIQILKKCN- 95 Query: 532 HAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVE-ILRQATMGLSHLH 590 + +VV Y+ + K +I ++ CS + + + + + K + IL+Q+ +GL +LH Sbjct: 96 NPYVVSYFGSIMLKNKYWILMDYCSLSSFNDIMQSIGKTFKEKEISLILQQSLLGLVYLH 155 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650 S I+HRD+K N+LL TG+V+ I+DFG+S+++ + +FS+ S + GT W+AP Sbjct: 156 SKQIIHRDIKSANILL---DETGQVK--IADFGVSQQI---QSTFSKGS-IAGTPYWMAP 206 Query: 651 EMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTG 695 E++N ID++SLG V L+ G+ P +V +A + G Sbjct: 207 EILNQTDYNNKIDVWSLGIV-AIELADGEPPLSEVNPMRAMYMIG 250 >UniRef50_A0CA77 Cluster: Chromosome undetermined scaffold_160, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_160, whole genome shotgun sequence - Paramecium tetraurelia Length = 480 Score = 92.3 bits (219), Expect = 6e-17 Identities = 86/288 (29%), Positives = 142/288 (49%), Gaps = 23/288 (7%) Query: 483 TDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAH--VVRYY 539 ++Q LG+G G ++ + + VAVK +LP+ E+ +L E H+H +VR Sbjct: 11 SNQQLGQGVFGQVYLAKKKTTQEQVAVK-ILPKNNQLTLSEIEILNELVKHSHPAIVRII 69 Query: 540 CTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRD 598 Y+ E C S TL D+++KK + + +EIL Q GL +LH ++IVHRD Sbjct: 70 DVYDQGTQVYVVQEFCNSGTLFDFMKKKPQYLGEEHCIEILEQVAQGLDYLHKINIVHRD 129 Query: 599 VKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERT 658 +KP N+L + + G++ ISDFGL IG V + + GT ++APE+I+G Sbjct: 130 IKPENILRT--TYNGQIYYKISDFGLG---CIGDVKLTSK---FGTAYYVAPEIIDGRAE 181 Query: 659 ----TTSIDIFSLGCVFYYVLSK----GQHPFGDVLRRQANILTGDYNLDHLDKILPEEE 710 ++DI++LG +F +L H +V + N ++ LP + Sbjct: 182 LYGYDKTVDIWALGLMFDELLHGTPFFDGHTEDEVFIKIRNEPYYPRKHEYSGSRLPPRK 241 Query: 711 LVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQV 758 +V IL+ MI+ +P+ R IL + KQ++ N + +QV Sbjct: 242 QIVANILM-GMINKEPNQRKSLPWILDLIRQY-KQNVNNSSISLLNQV 287 >UniRef50_Q5AHF2 Cluster: Potential pheromone pathway MAPKKK; n=3; Saccharomycetales|Rep: Potential pheromone pathway MAPKKK - Candida albicans (Yeast) Length = 823 Score = 92.3 bits (219), Expect = 6e-17 Identities = 64/215 (29%), Positives = 109/215 (50%), Gaps = 15/215 (6%) Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEIL 579 RE+ LL+E + H ++VRY+ + D+ F I LE ++Q + FE + + Sbjct: 600 REMMLLKELN-HENIVRYFGSTTDENFLNIFLEYVPGGSVQSMLNSYGPFEEPLIR-NFV 657 Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNI------GRV 633 RQ +GLS+LH DI+HRD+K N+L+ + GT I DFG+SKK++ Sbjct: 658 RQVLIGLSYLHGEDIIHRDIKGANILIDI-KGT----VKIGDFGISKKVSAIDEEDEDFK 712 Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANIL 693 +R+ + G+ W+APE++ T DI+S+GC+ + + G+HPF ++ + QA Sbjct: 713 KTGKRASLQGSVFWMAPEVVKQTTYTKKADIWSVGCLIVEMFT-GRHPFPELSQMQALFK 771 Query: 694 TGDYNLDHLDKILPEEELVVIKILIRAMISAKPSA 728 G++ + + E +K +P A Sbjct: 772 IGNHITPQIPEWCTNEAKEFLKKTFEINFEMRPDA 806 >UniRef50_Q01YI9 Cluster: Serine/threonine protein kinase; n=1; Solibacter usitatus Ellin6076|Rep: Serine/threonine protein kinase - Solibacter usitatus (strain Ellin6076) Length = 431 Score = 91.9 bits (218), Expect = 8e-17 Identities = 70/226 (30%), Positives = 114/226 (50%), Gaps = 20/226 (8%) Query: 475 KIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDA--- 531 KIG FQ + + G + F RG D ++VAVK + T RE RE++ Sbjct: 3 KIGP--FQLLETIHLGSQPLFRARGK-DGQEVAVKAIPVANLTDETRE-RFTREAETCRK 58 Query: 532 --HAHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSH 588 H +++R + T Y A+EL + A L + + +F+ + + I+ Q + GL + Sbjct: 59 LDHPNIIRVFETGEADGMLYQAMELLAGADLGKVMSEGRHFDWEA-KLSIMEQVSSGLQY 117 Query: 589 LHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWI 648 H +VHRD+KP N+ L +G V+ + DFG+ + + ++ GT ++ Sbjct: 118 AHEHQLVHRDIKPANLFLE---NSGRVKVL--DFGM---VRVAESELTKAGSSLGTLNYM 169 Query: 649 APEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILT 694 +PE I GER T + D+FS G VFY L+ G+HPF R A +++ Sbjct: 170 SPEQIRGERVTPATDVFSAGIVFYQ-LASGRHPFSSRDRGLAQVVS 214 >UniRef50_Q86SG6 Cluster: Serine/threonine-protein kinase Nek8; n=26; Deuterostomia|Rep: Serine/threonine-protein kinase Nek8 - Homo sapiens (Human) Length = 692 Score = 91.9 bits (218), Expect = 8e-17 Identities = 77/282 (27%), Positives = 142/282 (50%), Gaps = 24/282 (8%) Query: 481 FQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLPECFTFADREVAL----LRESDAHAHV 535 ++ +V+G+G G + D++ V +K++ E T +R+ A + + H +V Sbjct: 4 YERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNV 63 Query: 536 VRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSV-EILRQATMGLSHLHSMD 593 + YY + + IA+E TL ++++K+ N + +++ Q + L H+H+ Sbjct: 64 IEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL 123 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 I+HRD+K N+LL + I DFG+SK L+ S S+ V GT +I+PE+ Sbjct: 124 ILHRDLKTQNILLDKH----RMVVKIGDFGISKILS----SKSKAYTVVGTPCYISPELC 175 Query: 654 NGERTTTSIDIFSLGCVFYYVLS-KGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712 G+ DI++LGCV Y + S K ++ I++G + D+ PE Sbjct: 176 EGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTF-APISDRYSPE---- 230 Query: 713 VIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDV 754 ++ L+ +++S +P+ RPP I+ P+ C +++LN DV Sbjct: 231 -LRQLVLSLLSLEPAQRPPLSHIMAQPL--CIRALLNLHTDV 269 >UniRef50_Q8SQT4 Cluster: NIMA-LIKE SER/THR PROTEIN KINASE; n=1; Encephalitozoon cuniculi|Rep: NIMA-LIKE SER/THR PROTEIN KINASE - Encephalitozoon cuniculi Length = 300 Score = 91.5 bits (217), Expect = 1e-16 Identities = 71/204 (34%), Positives = 108/204 (52%), Gaps = 14/204 (6%) Query: 487 LGKGCEGTFVYRGTF--DKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERD 544 L +G GT T + VA K +L +A++EV +L S +H VVR Sbjct: 25 LSRGAHGTVYLLETEAPTREKVACKSMLKRYRRYAEKEVEML-SSISHRRVVRLLDFFPT 83 Query: 545 KQFRYIALELCS-ATLQDYVEKKLNFECKI--DSV-EILRQATMGLSHLHSMDIVHRDVK 600 K I LE + +L + +E + ++ D V +L QA GL +LHS I+HRDVK Sbjct: 84 KSGLSIILEYLNYGSLHEMIEYLMENGYRVAGDLVWSVLAQAADGLRYLHSKQIIHRDVK 143 Query: 601 PHNVLLSMPSGTGE--VRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERT 658 P N+L++ E + + DF L+K L G+ S G+ GT ++APE+++GER Sbjct: 144 PSNILMNRTLVQKEELLEFKLCDFSLAKNL-CGKESVC---GIVGTPSYMAPEVVSGERY 199 Query: 659 TTSIDIFSLGCVFYYVLSKGQHPF 682 +TS+DI+SLG Y +L+ + PF Sbjct: 200 STSVDIWSLGISIYELLTL-RRPF 222 >UniRef50_A5DV77 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 908 Score = 91.5 bits (217), Expect = 1e-16 Identities = 61/185 (32%), Positives = 104/185 (56%), Gaps = 15/185 (8%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEI 578 +RE+ LL+E + H ++VRY+ ++ D ++ I LE ++Q + FE + Sbjct: 684 EREMMLLKELN-HENIVRYFGSKTDDKYLNIFLEYVPGGSVQTMLNSYGPFEEPLIR-NF 741 Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNI---GRVSF 635 +RQ +GLS+LH DI+HRD+K N+L+ + GT I DFG+SKK++ F Sbjct: 742 IRQVLIGLSYLHGEDIIHRDIKGANILIDI-KGT----VKIGDFGISKKVSTIDEEDEDF 796 Query: 636 SR---RSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANI 692 R R+ + G+ W+APE++ T DI+S+GC+ + + G+HPF ++ + QA Sbjct: 797 KRTGKRASLQGSVFWMAPEVVKQTTYTKKADIWSVGCLIVEMFT-GKHPFPNLSQMQALF 855 Query: 693 LTGDY 697 G++ Sbjct: 856 KIGNH 860 >UniRef50_Q7UEM6 Cluster: Serine/threonine protein kinase; n=1; Pirellula sp.|Rep: Serine/threonine protein kinase - Rhodopirellula baltica Length = 856 Score = 91.1 bits (216), Expect = 1e-16 Identities = 69/215 (32%), Positives = 106/215 (49%), Gaps = 16/215 (7%) Query: 476 IGKIT-FQTDQVLGKGCEGTFVYR-GTFDKRDVAVKRLLPECFTFADREVALLRESDA-- 531 IG+ ++ Q+LG+G G + T R AVK L PE T A RE+ + Sbjct: 112 IGRFARYEIHQILGRGGMGIVMEATDTSLGRRCAVKVLAPELATSAAARKRFSREAKSAA 171 Query: 532 ---HAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLS 587 H HVV + + Y+ + + +LQ V++ I++V I Q GL+ Sbjct: 172 AVVHPHVVPIQTVDEHEGLPYLVMPVVDGPSLQQRVDRDGPLSL-IETVRIASQIADGLA 230 Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647 H +VHRD+KP NVLL G R I+DFGL++ + S +R + GT + Sbjct: 231 AAHEQGLVHRDIKPANVLLE----NGVERVQITDFGLARA--VDDASMTRSGVIAGTPQY 284 Query: 648 IAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 ++PE +G+ D+FSLG V +++LS G+ PF Sbjct: 285 MSPEQAHGDSIDHRSDLFSLGSVIHFMLS-GRSPF 318 >UniRef50_A6FXR0 Cluster: Serine/threonine protein kinase; n=1; Plesiocystis pacifica SIR-1|Rep: Serine/threonine protein kinase - Plesiocystis pacifica SIR-1 Length = 745 Score = 91.1 bits (216), Expect = 1e-16 Identities = 71/208 (34%), Positives = 104/208 (50%), Gaps = 17/208 (8%) Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLL------PECFTFADREVALLRESDAH 532 +Q + +G G G VYRGT D VA+K + P REV L D H Sbjct: 53 YQIESFIGSGGMGR-VYRGTQLSLDRPVAIKVMRLERSADPAMVRRFLREVRLSSRLD-H 110 Query: 533 AHVVRYYCTERDKQFR-YIALELCSA-TLQDYV-EKKLNFECKIDSVEILRQATMGLSHL 589 ++VR ++ R Y+ +EL TL DYV E L +E + E+ Q G+ Sbjct: 111 PNIVRVIDGGNTREGRCYLIMELLEGVTLGDYVPEGGLRWE---EVRELFGQLCSGVQAF 167 Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649 H +VHRD+KP+NVLL + G G R I DFGL++ L+ + GT G++A Sbjct: 168 HRAGLVHRDLKPNNVLL-VDDGDGGRRVKIFDFGLARDLDPDTTGLTAEGEFLGTPGYVA 226 Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSK 677 PE ++ T D+++LG V Y++L+K Sbjct: 227 PEQMSSGEVTLQTDVYALGAVLYFMLTK 254 >UniRef50_A4A0R5 Cluster: Probable serine/threonine-protein kinase pknB; n=1; Blastopirellula marina DSM 3645|Rep: Probable serine/threonine-protein kinase pknB - Blastopirellula marina DSM 3645 Length = 450 Score = 91.1 bits (216), Expect = 1e-16 Identities = 71/205 (34%), Positives = 103/205 (50%), Gaps = 19/205 (9%) Query: 487 LGKGCEG-TFVYRGTFDKRDVAVK-----RLLPECFTFADREVALLRESDAHAHVVRYYC 540 +G+G G F F R VA+K R PE T RE+ + + D H +VR Y Sbjct: 81 IGQGGMGQVFKAEHNFMGRQVAIKVLPLQRSTPEAITRFMREIRMQAQLD-HPCLVRAYD 139 Query: 541 TERDKQFRYIALELCSAT-LQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599 +D Y+ E T L+ + K + + + I+ A GL + HS D+ HRDV Sbjct: 140 AGQDGNVHYLVTEYVPGTDLRRLIRAKRHLT-QYHAATIVSHAARGLEYAHSKDLCHRDV 198 Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG-VTGTDGWIAPEMINGERT 658 KP N+L+ T E +A +SD GL+ +N S + SG + GT ++APE I Sbjct: 199 KPGNILV-----TPEGQAKVSDLGLADFMN--EASSAGASGKIVGTIDYLAPEQIRDPLD 251 Query: 659 TTSI-DIFSLGCVFYYVLSKGQHPF 682 + + DI+SLGC FYY L+ G+ PF Sbjct: 252 VSPLWDIYSLGCTFYYALT-GKVPF 275 >UniRef50_Q4RL54 Cluster: Chromosome 12 SCAF15023, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 12 SCAF15023, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 735 Score = 90.6 bits (215), Expect = 2e-16 Identities = 67/222 (30%), Positives = 105/222 (47%), Gaps = 15/222 (6%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEIL 579 DRE+ L R H H+V +Y DK+ YI LE CS ++ K + + L Sbjct: 99 DREIELHRILH-HKHIVHFYHHFEDKENIYILLEYCSRKSLAHILKARKVLTEPEVRYYL 157 Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639 RQ GL +LH +I+HRD+K N ++ + + DFGL+ KL + +RR Sbjct: 158 RQIVSGLRYLHEQEILHRDLKLGNFFVNE-----SMELKVGDFGLAAKLE---PAGNRRK 209 Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNL 699 + GT +++PE++N + DI++LGCV Y +L G+ PF N+ + Sbjct: 210 TICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTML-LGRPPF-----ETTNLKETYRCI 263 Query: 700 DHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741 LP K LI +++ P RP + IL++ F Sbjct: 264 REARYSLPSSLSAQAKQLITNLLAKTPEDRPNLDLILRHDFF 305 >UniRef50_A0CWQ7 Cluster: Chromosome undetermined scaffold_3, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_3, whole genome shotgun sequence - Paramecium tetraurelia Length = 498 Score = 90.6 bits (215), Expect = 2e-16 Identities = 77/285 (27%), Positives = 148/285 (51%), Gaps = 28/285 (9%) Query: 474 MKIGKIT--FQTDQVLGKGCEGTF---VYRGTFDKR---DVAVKRLLPECFTFADREVAL 525 +K G IT + +++LG+G G ++ + +R ++ K++L E EV+L Sbjct: 46 LKTGDITDNYIMNKILGEGSYGQVRLVQHKKSGQQRAMKQISKKKILKEQEEAMFSEVSL 105 Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATM 584 L+ D + ++V+ + +D Q Y+ E L L + + K F ++ + E ++Q Sbjct: 106 LKNMD-YPNIVKLFELYQDSQNYYLVTEYLNGGELLEKLTKLQTFNERM-AAEYMKQVLS 163 Query: 585 GLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGT 644 L++ H+ +I+HRD+KP N++L+ +++ + DFG +K+ V+ ++ V GT Sbjct: 164 ALAYCHAQNIIHRDMKPSNIMLASTDPQSKIK--VIDFGTAKRF----VNGQTQTQVIGT 217 Query: 645 DGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF----GDVLRRQANILTGDYNLD 700 ++APE+I+ + T DI+S G + Y +L+ G+ PF ++ + +NI +G YN Sbjct: 218 PLYLAPEVID-KNYTEKCDIWSCGVILYQILT-GKFPFESKVSNLQQLFSNIKSGKYNFT 275 Query: 701 HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQ 745 + E + LI++M+ P+ RP + IL P W K+ Sbjct: 276 SKEFTTLSYE---AQELIKSMLQFDPNKRPSAQKILDDP--WIKE 315 >UniRef50_A0BDG2 Cluster: Chromosome undetermined scaffold_100, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_100, whole genome shotgun sequence - Paramecium tetraurelia Length = 699 Score = 90.6 bits (215), Expect = 2e-16 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 8/190 (4%) Query: 542 ERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKP 601 E Q I + L DYV+ K + + ++ I Q LS++HS+ IVHRD+KP Sbjct: 495 ENRDQIHIITEIIEDGDLFDYVQNKQYLD-ESEAAIIFNQLLDALSYIHSIGIVHRDIKP 553 Query: 602 HNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTS 661 N+L+ + T + +I DFGL+ L+ + + ++ GT + APEM+ + T S Sbjct: 554 ENILMILDKNTVKQIKLI-DFGLANHLSKIQKNNEYQNYHCGTCNYQAPEMLQFQEITFS 612 Query: 662 IDIFSLGCVFYYVLSKGQHPF-GDV-LRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719 +D+F+LG + YY+LS G PF D+ L N + G YN+D EE K LI Sbjct: 613 VDVFALGVILYYMLS-GYLPFDSDIPLEIIQNTIDGIYNMDDYHWQCVSEE---AKDLIV 668 Query: 720 AMISAKPSAR 729 A++ +PS R Sbjct: 669 ALLHNQPSKR 678 >UniRef50_A7M6H7 Cluster: Calcium/calmodulin-dependent protein kinase; n=15; Dikarya|Rep: Calcium/calmodulin-dependent protein kinase - Coprinus cinereus (Inky cap fungus) (Hormographiella aspergillata) Length = 488 Score = 90.6 bits (215), Expect = 2e-16 Identities = 71/285 (24%), Positives = 134/285 (47%), Gaps = 19/285 (6%) Query: 481 FQTDQVLGKGC-----EGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRE-SDAHAH 534 ++T + LG G E + G + V K+L+ E+A+L++ S H + Sbjct: 107 YRTGKTLGSGTYAIVKEAIHITTGKYYACKVINKKLMEGREHMVRNEIAVLKKISSGHPN 166 Query: 535 VVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 +V + Y+ +LC+ L D + K N+ + D+ +++R + ++H+ Sbjct: 167 IVTLHDYFETAHNLYLVFDLCTGGELFDRICAKGNYY-EADAADLVRTIFKAVEYIHNSG 225 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 +VHRD+KP N+L + E MI+DFGLS+ + FS + + GT G++APE+ Sbjct: 226 VVHRDLKPENLLFK--TQAEEAAIMIADFGLSRVME--EEKFSLLTEICGTPGYMAPEIF 281 Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDHLDKILPEEEL 711 +D++++G + Y++L+ G PF ++Q I+ GDY + + E Sbjct: 282 KRTGHGKPVDVWAMGVITYFLLA-GYTPFDRESQQQEMEAIIAGDYKFEPAE--YWENVS 338 Query: 712 VVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSD 756 K +R ++ P+ RP L + W +F+ + +D Sbjct: 339 ETAKDFVRTCLTIDPNKRPTATEALAHK--WLADKEPHFVANPAD 381 >UniRef50_UPI0000ECAA30 Cluster: Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (hIRE2p) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.2; n=3; Gallus gallus|Rep: Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (hIRE2p) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.2 - Gallus gallus Length = 87 Score = 90.2 bits (214), Expect = 2e-16 Identities = 41/77 (53%), Positives = 53/77 (68%) Query: 794 DLRTRRTYRGDRVAHLLRAIRNKKHHYRELESDVRDSLGKLPDGFVSYWLTRFPLLLPHV 853 DLR RTY+G V LLRA+RNKKHHY EL ++VR++LG +PDGF+ Y+ +RFP LL H Sbjct: 2 DLRKFRTYKGSSVRDLLRAMRNKKHHYHELPAEVREALGSVPDGFMQYFTSRFPRLLLHT 61 Query: 854 WLQMQQYRDEDILQTYY 870 MQ E + + YY Sbjct: 62 HSAMQLCAHERLFRPYY 78 >UniRef50_A3ZYY0 Cluster: Serine/threonine protein kinase; n=1; Blastopirellula marina DSM 3645|Rep: Serine/threonine protein kinase - Blastopirellula marina DSM 3645 Length = 897 Score = 90.2 bits (214), Expect = 2e-16 Identities = 70/216 (32%), Positives = 112/216 (51%), Gaps = 19/216 (8%) Query: 476 IGKIT-FQTDQVLGKGCEGTFVYRGTFDK--RDVAVKRLLPECFTFADREVALLRESDA- 531 +G+++ ++ QVLG+G G V++ +K R VA+K + PE + LRE+ A Sbjct: 94 LGRLSHYEVRQVLGRGGCG-IVFKAFDEKLQRTVAIKVIAPELSATSPARKRFLREARAA 152 Query: 532 ----HAHVVRYYCTERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGL 586 H VV Y E + Y+ +E L T+QD +++ F + + RQ GL Sbjct: 153 AGVRHNSVVSIYAVE-NLPIPYLVMEYLDGGTMQDKLDQSGPFALP-EILLFGRQIAEGL 210 Query: 587 SHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDG 646 + H+ ++HRD+KP N+LL G +SDFGL++ ++ R++ S V GT Sbjct: 211 AAAHAQGLIHRDIKPCNILLD----AGGQSVKLSDFGLARTMDDARLTQS--GAVAGTPL 264 Query: 647 WIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 +++PE GE D+FSLG V YV+ G+ PF Sbjct: 265 YMSPEQARGETLDQRSDLFSLGSVL-YVMCSGRPPF 299 >UniRef50_Q4Q6Y5 Cluster: Protein kinase-like protein; n=3; Leishmania|Rep: Protein kinase-like protein - Leishmania major Length = 1899 Score = 89.8 bits (213), Expect = 3e-16 Identities = 81/288 (28%), Positives = 133/288 (46%), Gaps = 24/288 (8%) Query: 480 TFQTDQVLGKGCEGTFVYRGTFDK-RDVAVKRL-----LPECFTFADREVALLRESDAHA 533 TF LGKG GT V+ G + VAVK + PE + EV +LRE +H Sbjct: 1559 TFSCGPALGKGSYGT-VHLGILTNGKMVAVKYVNVVSESPETLASVEAEVNMLREL-SHP 1616 Query: 534 HVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592 +++RY+ + + +E +L V+K + + + Q GL +LH Sbjct: 1617 NIIRYFGAHTIQDTMLVFMEFAVGGSLTSIVKKFTHLTEPVMQLYTF-QILKGLQYLHDK 1675 Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKL-NIGRVSFSRRSGVTGTDGWIAPE 651 +VHRD+K N+L+ G G A ++DFG SK L NI S + G+ W+APE Sbjct: 1676 GVVHRDIKGENILID---GYGV--AKLADFGCSKSLANIANSSQVGCGTLVGSPFWMAPE 1730 Query: 652 MINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKI--LPEE 709 +I E T DI+S+GC +L+ G+ P+ + N+ + + + + I +PEE Sbjct: 1731 VIRSEAYGTKADIWSVGCTVVEMLNGGEPPWREEF---DNVYSAMFYVGSTNDIPQIPEE 1787 Query: 710 ELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQ-SILNFLQDVSD 756 + + + R + +L++P W K + + +D SD Sbjct: 1788 TSDPCRAFLFRCFEREVMKRASADELLQHP--WLKSAAAASHAEDSSD 1833 >UniRef50_Q233F7 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 768 Score = 89.8 bits (213), Expect = 3e-16 Identities = 60/211 (28%), Positives = 111/211 (52%), Gaps = 11/211 (5%) Query: 478 KITFQTDQVLGKGCEGTFVYRG--TFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535 K FQ + LG+G GT VY+ D+++ A+K L + + E LL++ D H H+ Sbjct: 14 KYQFQLSEKLGQGAFGT-VYKAIDNTDEQECAIKILYKSNMSCSLIEGRLLQQLD-HPHI 71 Query: 536 VRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVE---ILRQATMGLSHLHS 591 V++ K I +EL T+ ++++ E E I++ + ++HS Sbjct: 72 VKFKRVGETKHAFVIIMELMKGGTIAQLIKQRKQNEQPFTDDEASTIMKCILSAVDYMHS 131 Query: 592 MDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPE 651 +I+HRD+KP N+LL+ P+ V+ ++DFGL + + +++ GT +++PE Sbjct: 132 QNILHRDLKPENILLADPNDLTSVK--VADFGLGIQYST-EMTYRSFLQQCGTVLFMSPE 188 Query: 652 MINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 + + + +D++S G + Y +LS G+HPF Sbjct: 189 QLKNQPYSKPVDLWSCGIIMYMILSMGRHPF 219 >UniRef50_A0C693 Cluster: Chromosome undetermined scaffold_151, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_151, whole genome shotgun sequence - Paramecium tetraurelia Length = 515 Score = 89.8 bits (213), Expect = 3e-16 Identities = 67/209 (32%), Positives = 106/209 (50%), Gaps = 18/209 (8%) Query: 486 VLGKGCEGTFV--YRGTFDKRDV-AVKRL----LPECFTFADREVALLRESDAHAHVVRY 538 VLGKG GT Y+ D V A+K + + + E +LR+ D H ++VR+ Sbjct: 30 VLGKGSFGTVKVGYKDGPDGEQVYAIKTINKVRVADKTQMIQEEFEILRKMD-HPNIVRF 88 Query: 539 YCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHR 597 Y D F Y +E C L + V K +F+ + + ++R+ +++LHS ++HR Sbjct: 89 YEMYEDDMFIYFVMEHCKGGNLLERVLSKGSFD-ENKACIVMRKLFSAIAYLHSQGVMHR 147 Query: 598 DVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIG----RVSFSRRSGVTGTDGWIAPEMI 653 D+KP N+LLS E++ I DFGLSKKL + R+ GT ++APE++ Sbjct: 148 DLKPENILLSNEKDDAEIK--IIDFGLSKKLKESDKDRKKQLQRKQSQVGTPLYVAPEVV 205 Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 G D +++GC+ Y VL + PF Sbjct: 206 TGV-YNQKCDDWAVGCIMYIVLC-SEPPF 232 >UniRef50_Q9HFR3 Cluster: Mekk; n=1; Pneumocystis carinii|Rep: Mekk - Pneumocystis carinii Length = 823 Score = 89.8 bits (213), Expect = 3e-16 Identities = 66/221 (29%), Positives = 108/221 (48%), Gaps = 15/221 (6%) Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEIL 579 RE++LL+E H ++V+Y + D+ LE ++ + FE + + Sbjct: 599 REISLLKELH-HENIVQYLGSSMDETHLTFFLEYVPGGSVTALLNNYGAFEEPLIR-NFV 656 Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSR-- 637 RQ GL++LH+ I+HRD+K N+L+ G ISDFG+SKK+ +S +R Sbjct: 657 RQILKGLNYLHNKKIIHRDIKGANILVDNKGG-----IKISDFGISKKVEANLLSMTRNQ 711 Query: 638 RSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY 697 R + G+ W+APE++ T DI+SLGC+ + + G+HPF + + QA G Y Sbjct: 712 RPSLQGSVYWMAPEVVKQTLYTRKADIWSLGCLIVEMFT-GKHPFPKMNQLQAIFKIGQY 770 Query: 698 NLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKY 738 + +PE + + + ARP +LKY Sbjct: 771 ----VSPDIPEHCTSEARHFLEKIFEPDYHARPTAADLLKY 807 >UniRef50_A6CBR9 Cluster: Serine/threonine protein kinase; n=1; Planctomyces maris DSM 8797|Rep: Serine/threonine protein kinase - Planctomyces maris DSM 8797 Length = 1576 Score = 89.4 bits (212), Expect = 4e-16 Identities = 66/212 (31%), Positives = 108/212 (50%), Gaps = 22/212 (10%) Query: 481 FQTDQVLGKGCEGTFVYRGTFDK--RDVAVKRLLPECFTFADREVALLRESDA-----HA 533 +Q ++G+G G V+R K R VA+K + P + + +RE+ A H Sbjct: 115 YQIYNIIGQGGMG-IVFRALDPKLNRIVAIKVMSPLLAVNPNAKKRFIREAQAAAAVSHP 173 Query: 534 HVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILR---QATMGLSHLH 590 H+V + + DK Y+ +E + +++KL+ + EILR Q GL+ H Sbjct: 174 HIVTIHAVDEDK-LPYLVMEY---VVGQSLQEKLDKVGSLKVTEILRIGSQIAEGLAAAH 229 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650 ++HRD+KP N+LL G R I+DFGL++ ++ V+ +R V+GT +++P Sbjct: 230 KQGLIHRDIKPANILLE----NGVERVKITDFGLARAVD--DVTITRTGEVSGTPQYMSP 283 Query: 651 EMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 E G+R D+FSLG V Y + G+ PF Sbjct: 284 EQATGDRIDQRSDLFSLGAVL-YAMCTGRSPF 314 >UniRef50_Q4DQP8 Cluster: Protein kinase-like protein, putative; n=2; Trypanosoma cruzi|Rep: Protein kinase-like protein, putative - Trypanosoma cruzi Length = 1758 Score = 89.4 bits (212), Expect = 4e-16 Identities = 80/270 (29%), Positives = 128/270 (47%), Gaps = 23/270 (8%) Query: 481 FQTDQVLGKGCEGTFVYRGTFDK-RDVAVKRL-----LPECFTFADREVALLRESDAHAH 534 F LG G GT V+ G R VAVK L + + + +EV +L++ +H + Sbjct: 1482 FSCGPALGSGSYGT-VHLGILKSGRLVAVKYLSIQNSVKDALSQVQKEVGVLKKL-SHPN 1539 Query: 535 VVRYY--CTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVE--ILRQATMGLSHLH 590 ++RY+ CT+ D YI L + A NF +SV Q +GL +LH Sbjct: 1540 IIRYFGCCTDND----YILLFMEFAVAGSLTSIVRNFTGLNESVIQFYTYQMLLGLRYLH 1595 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKL-NIGRVSFSRRSGVTGTDGWIA 649 +VHRD+K N+L+ G G V+ ++DFG SK L I S + + G+ W+A Sbjct: 1596 QKGVVHRDIKGENILVD---GFGAVK--LADFGSSKILPGISDRSRAGCETLIGSPFWMA 1650 Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEE 709 PE+I E T DI+S+GC +L+ G P+ + +++ D + KI PE+ Sbjct: 1651 PEVIRNEPYGTKTDIWSVGCTVVEMLNGGTPPWQEEFENVYSLMYYVGTTDSIPKI-PED 1709 Query: 710 ELVVIKILIRAMISAKPSARPPCETILKYP 739 + +R + RP + +L++P Sbjct: 1710 TSESCRDFLRMCFQRDTTKRPSSDELLQHP 1739 >UniRef50_Q9FKL3 Cluster: Similarity to protein kinase; n=1; Arabidopsis thaliana|Rep: Similarity to protein kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 1054 Score = 89.0 bits (211), Expect = 5e-16 Identities = 80/259 (30%), Positives = 130/259 (50%), Gaps = 25/259 (9%) Query: 487 LGKGCEGTFVYRGTFDKRDVAVKRLLPECFTF--ADRE--------VALLRESDAHAHVV 536 LG G G+ VY G + DVA+KR+ CF ++RE ALL S H +VV Sbjct: 787 LGHGTYGS-VYHGKWKGSDVAIKRIKASCFAGKPSERERLIEDFWKEALLLSSLHHPNVV 845 Query: 537 RYYCTERDK---QFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 +Y RD +A + + +L+ +++KK + + I G+ +LH + Sbjct: 846 SFYGIVRDGPDGSLATVAEFMVNGSLKQFLQKKDRTIDRRKRLIIAMDTAFGMEYLHGKN 905 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 IVH D+K N+L++M + I D GLSK VS GV GT W+APE++ Sbjct: 906 IVHFDLKCENLLVNMRDPQRPI-CKIGDLGLSKVKQKTLVS----GGVRGTLPWMAPELL 960 Query: 654 NGERTTTS--IDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEEL 711 +G+ S ID++S G V + +L+ G+ P+ D+ A+I+ G N + L +P+ Sbjct: 961 SGKSNMVSEKIDVYSFGIVMWELLT-GEEPYADM--HCASIIGGIVN-NALRPKIPQWCD 1016 Query: 712 VVIKILIRAMISAKPSARP 730 K L+ + +++P+ RP Sbjct: 1017 PEWKGLMESCWTSEPTERP 1035 >UniRef50_Q9VW24 Cluster: CG8789-PA, isoform A; n=3; Diptera|Rep: CG8789-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 977 Score = 89.0 bits (211), Expect = 5e-16 Identities = 75/254 (29%), Positives = 127/254 (50%), Gaps = 23/254 (9%) Query: 487 LGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQ 546 LG G +G V+ G VAVK++ + ++ LR+ D H +++++ Sbjct: 167 LGSGAQGA-VFSGRLKNETVAVKKVKE----LKETDIKHLRKLD-HENIIKFKGVCTQSP 220 Query: 547 FRYIALELCS-ATLQDYV-EKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNV 604 I +E C LQ+ + E+++ ++ V +Q +G+ +LHS I+HRD+K N+ Sbjct: 221 VFCIIMEFCPYGPLQNILKEEQVMLPSRL--VSWSKQIALGMQYLHSHKIIHRDLKSPNI 278 Query: 605 LLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDI 664 L+S T EV ISDFG S++ N S + GT W+APE+I E + +DI Sbjct: 279 LIS----TNEV-VKISDFGTSREWN----EISTKMSFAGTVAWMAPEVIRNEPCSEKVDI 329 Query: 665 FSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISA 724 +S G V + +L+ + P+ DV + I+ G N + L ++P K+L++ + Sbjct: 330 WSYGVVLWEMLT-CEIPYKDV--DSSAIIWGVGN-NSLKLLVPSTCPEGFKLLVKLCWKS 385 Query: 725 KPSARPPCETILKY 738 KP RP IL + Sbjct: 386 KPRNRPSFRQILSH 399 >UniRef50_Q6BFD3 Cluster: Calcium-dependent protein kinase, putative; n=4; Paramecium tetraurelia|Rep: Calcium-dependent protein kinase, putative - Paramecium tetraurelia Length = 539 Score = 89.0 bits (211), Expect = 5e-16 Identities = 72/242 (29%), Positives = 119/242 (49%), Gaps = 23/242 (9%) Query: 509 KRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKL 567 KR + + RE+ +L + D H +++R Y T D ++ + +E C L + + +K Sbjct: 69 KRRIGQRLHLIQRELEILVQLD-HPNIIRVYETYEDMRYYHFVMEYCRGGELFERIVRKG 127 Query: 568 NFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKK 627 F + S+ +++Q + ++H + HRD+KP N++L+ P ++R I DFGLSKK Sbjct: 128 VFSERKCSI-LMKQLFSAVHYMHQQGVTHRDLKPENLMLASPDDDLDIR--IIDFGLSKK 184 Query: 628 ------LNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHP 681 N GR S R GT ++APE++ G+ + T D +SLGC+ YVL G+ P Sbjct: 185 YPPPQSANQGR-SQVRTQTKVGTPIYVAPEVLQGKYSQT-CDEWSLGCIM-YVLLCGEPP 241 Query: 682 FGD----VLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILK 737 F VL + +N + I E +++VI++L P R C L Sbjct: 242 FFSNNLKVLEEKIQNKDIQFNENSWQNISKEAKMLVIRLL-----DKNPKKRITCAQALS 296 Query: 738 YP 739 P Sbjct: 297 SP 298 >UniRef50_A0BFB3 Cluster: Chromosome undetermined scaffold_103, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_103, whole genome shotgun sequence - Paramecium tetraurelia Length = 418 Score = 89.0 bits (211), Expect = 5e-16 Identities = 52/149 (34%), Positives = 83/149 (55%), Gaps = 11/149 (7%) Query: 532 HAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLH 590 H ++VR + ++ Y+ LEL + TL++Y+ KK+ + + V IL+Q + HLH Sbjct: 180 HQNIVRLLGISKTQRHFYLLLELPNGDTLKNYMCKKIKLS-EEEIVGILKQLLQAIDHLH 238 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650 S +I+HRD+KP N++L + + DFGL+ LN + + V GT G++AP Sbjct: 239 SNNIIHRDIKPENIILQ--HSDDQTLIKLIDFGLAANLNDPHIQYK----VCGTSGYVAP 292 Query: 651 EMINGERTT---TSIDIFSLGCVFYYVLS 676 E+IN T T DIFS G + Y +L+ Sbjct: 293 EVINNNGLTPYGTKCDIFSCGVILYQLLT 321 >UniRef50_UPI000155BF68 Cluster: PREDICTED: hypothetical protein, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: hypothetical protein, partial - Ornithorhynchus anatinus Length = 488 Score = 88.6 bits (210), Expect = 7e-16 Identities = 54/172 (31%), Positives = 90/172 (52%), Gaps = 10/172 (5%) Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633 D V ++RQ GL HLH IVH D+KP N+LLS G+V+ + DFGLS+KL+ G Sbjct: 20 DVVRLVRQILEGLCHLHQNGIVHLDLKPQNILLSALQPLGDVK--LVDFGLSRKLS-GPC 76 Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANIL 693 + GT ++APE++N + TT+ D++++G + Y +L+ PF ++ + Sbjct: 77 ELRE---ILGTPEYLAPEVLNYDPITTATDMWNIGIIAYMLLAHSS-PFAGEDNQETYLN 132 Query: 694 TGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQ 745 N+D+ + + + IR ++ P RP + L +P W +Q Sbjct: 133 ISQVNVDYSEPAFSSVSHLA-RDFIRTLLVKNPEERPTASSCLSHP--WLQQ 181 >UniRef50_A6G5N1 Cluster: Serine/threonine protein kinase; n=1; Plesiocystis pacifica SIR-1|Rep: Serine/threonine protein kinase - Plesiocystis pacifica SIR-1 Length = 653 Score = 88.6 bits (210), Expect = 7e-16 Identities = 67/213 (31%), Positives = 108/213 (50%), Gaps = 18/213 (8%) Query: 481 FQTDQVLGKGCEGTFVYRGTF----DKRDVAVK------RLLPECFTFADREVALLRESD 530 + ++++G+G G VY + + R+V VK L P+ +RE L + Sbjct: 24 YSLERLIGRGGMG-HVYLASMVEEGEAREVVVKVIAPTLALQPQAMARFEREAKRL-DGL 81 Query: 531 AHAHVVRYYCTERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589 H++VV Y + YI +E + L DY+ +K N + V I Q G+ H Sbjct: 82 RHSNVVEMYDYGHENGRAYIVMEHVDGELLNDYLSRKANLTLH-EFVPIAAQILKGVGHA 140 Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649 HS D++ RD+KP NV+L G +I DFGL+K L G +++ + GT G+++ Sbjct: 141 HSRDLMIRDIKPANVMLCERKGRANFVKII-DFGLAKMLE-GDEDITKQHFI-GTSGYLS 197 Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 PE I G +D+++LG +FY +LS G+ PF Sbjct: 198 PEQIKGLDIDLRVDVYALGVLFYQMLS-GRMPF 229 >UniRef50_A5ZMI3 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 738 Score = 88.6 bits (210), Expect = 7e-16 Identities = 74/222 (33%), Positives = 113/222 (50%), Gaps = 22/222 (9%) Query: 474 MKIGKITFQTDQVLGK-GCEGTF-VYRGTFDK--RDVAVKRLLPE-----CFTFADREVA 524 +K G I + ++LGK G G VY+ K R VAVK L PE F R A Sbjct: 2 LKTGMIIAERYEILGKIGTGGMADVYKAKDHKLNRFVAVKVLKPEFREDTTFIRKFRSEA 61 Query: 525 LLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQAT 583 H ++V + D+ YI +EL TL++Y+ KK K ++ I Q + Sbjct: 62 QAAAGLTHPNIVNVFDVGDDEGVYYIVMELIEGITLKEYIAKKGKLSIK-EATSIAIQVS 120 Query: 584 MGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTG 643 MGL H+ IVHRDVKP N+++S G+V+ ++DFG+++ + +S S V G Sbjct: 121 MGLEAAHNHGIVHRDVKPQNIIIST---DGKVK--VTDFGIARAASSNTIS----SNVMG 171 Query: 644 TDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GD 684 + + +PE + G + DI+SLG Y +++ G+ PF GD Sbjct: 172 SVHYSSPEQVRGGYSDEKSDIYSLGITLYEMVT-GRVPFDGD 212 >UniRef50_Q6EE08 Cluster: Fertilization-related kinase 2; n=1; Solanum chacoense|Rep: Fertilization-related kinase 2 - Solanum chacoense (Chaco potato) Length = 304 Score = 88.6 bits (210), Expect = 7e-16 Identities = 68/209 (32%), Positives = 102/209 (48%), Gaps = 20/209 (9%) Query: 476 IGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHV 535 + I + + +GKG EGT T + +AVK L C +E L E + + Sbjct: 1 MASIRWSRGRTIGKGAEGTVTLATTHNNFSIAVKSSLFSCSKSLQKEREFLNEFQDCSQI 60 Query: 536 VRYY---CTERDKQFRY-IALELC-SATLQDYVEKKL---NFECKIDSVEILRQATMGLS 587 +R + TE D Y I LE +L + KK +FE K S IL +GL Sbjct: 61 IRCFGADVTEEDNNILYNILLEYAIGGSLAHRIGKKSGLPDFEVKKYSKPIL----LGLR 116 Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647 +H VH D+KPHN+LL GT E RA I+DFG + K+ IG S++ + GT + Sbjct: 117 VVHGKGFVHGDIKPHNILL---VGT-EKRAKIADFGFASKVGIG----SKKRKLRGTPMY 168 Query: 648 IAPEMINGERTTTSIDIFSLGCVFYYVLS 676 +APE + + T DI++ GC + +++ Sbjct: 169 MAPESVLDDEYGTPADIWAFGCTVFEMIT 197 >UniRef50_P53355 Cluster: Death-associated protein kinase 1; n=68; Eumetazoa|Rep: Death-associated protein kinase 1 - Homo sapiens (Human) Length = 1432 Score = 88.6 bits (210), Expect = 7e-16 Identities = 67/228 (29%), Positives = 118/228 (51%), Gaps = 16/228 (7%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578 +REV++L+E H +V+ + +K + LEL + L D++ +K + + ++ E Sbjct: 62 EREVSILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLT-EEEATEF 119 Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638 L+Q G+ +LHS+ I H D+KP N++L + + R I DFGL+ K++ G + Sbjct: 120 LKQILNGVYYLHSLQIAHFDLKPENIML-LDRNVPKPRIKIIDFGLAHKIDFG----NEF 174 Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQ-ANILTGD 696 + GT ++APE++N E D++S+G + Y +LS G PF GD + AN+ + Sbjct: 175 KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANVSAVN 233 Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCK 744 Y + D+ + K IR ++ P R + L++P W K Sbjct: 234 YEFE--DEYFSNTS-ALAKDFIRRLLVKDPKKRMTIQDSLQHP--WIK 276 >UniRef50_UPI0000DB7108 Cluster: PREDICTED: similar to Death-associated protein kinase 1 (DAP kinase 1); n=1; Apis mellifera|Rep: PREDICTED: similar to Death-associated protein kinase 1 (DAP kinase 1) - Apis mellifera Length = 1110 Score = 88.2 bits (209), Expect = 9e-16 Identities = 55/170 (32%), Positives = 87/170 (51%), Gaps = 12/170 (7%) Query: 572 KIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIG 631 ++++ ++RQ M LSHLHS + H D+KP N+LLS P ++ + D GLS +L Sbjct: 126 ELEAAHVVRQVLMALSHLHSHQVAHLDIKPENILLSTPPPMPSIK--LIDLGLSHRL--- 180 Query: 632 RVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQ 689 V S + GT ++APE++N E + D++++G V Y+L G PF D Sbjct: 181 -VPGSEHRALFGTPEFVAPEIVNYEPLSLGTDLWAVG-VLTYILLSGASPFLGEDKQETY 238 Query: 690 ANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739 AN+ Y D+ E + K IR+++ P R E+ LK+P Sbjct: 239 ANVAACQYQFDNEYFSTVSE---IAKDFIRSLLIKDPKERGTAESCLKHP 285 >UniRef50_UPI00006CF2DC Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 842 Score = 88.2 bits (209), Expect = 9e-16 Identities = 75/264 (28%), Positives = 128/264 (48%), Gaps = 20/264 (7%) Query: 485 QVLGKGCEGTF--VYRGTFDKRD---VAVKRLLPECFTFADREVALLRESDAHAHVVRYY 539 +++ K EG+F V++G D +D AVK + E ++LR D H ++V++ Sbjct: 76 ELIEKIDEGSFGVVFKGR-DIQDGSLCAVKVTQNNKEKYTSIETSILRGLD-HPNIVKFK 133 Query: 540 CTERDKQFRYIALELCSA-TLQDYVE--KKLNFECKIDSVEILRQATMG-LSHLHSMDIV 595 +YI +E TLQ +E K N + ++ M L +H +++ Sbjct: 134 KFIELDSNKYIVMEYIGCGTLQQLIEERKAKNNPFNQQEISVIMSHLMSALKCMHENNVL 193 Query: 596 HRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMING 655 HRD+KP N+LL +++ +SDFGLS K G V F S GT ++APE++ Sbjct: 194 HRDIKPENILLGSKEDLSKLK--LSDFGLSVKYQDG-VPFKSYSQKCGTVIFMAPEILAE 250 Query: 656 ERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIK 715 ++ + IDI+S G + Y + + G+HPF + + NLD ++L E++ Sbjct: 251 KQYSKPIDIWSCGIILYMLYTMGKHPFKSSSISREEYIKKIINLDVSKEVLDEDDFP--- 307 Query: 716 ILIRAMISAKPSARPPCETILKYP 739 M++ +PS R +LK+P Sbjct: 308 ---SEMLNKEPSNRYTASQVLKHP 328 >UniRef50_A7QMH3 Cluster: Chromosome chr19 scaffold_126, whole genome shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome chr19 scaffold_126, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 1121 Score = 88.2 bits (209), Expect = 9e-16 Identities = 67/214 (31%), Positives = 107/214 (50%), Gaps = 22/214 (10%) Query: 487 LGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADRE-----VALLRESDA-----HAHVV 536 LG G GT VY G + DVA+KR+ CFT E + RE+D H +VV Sbjct: 846 LGSGTFGT-VYHGKWRGSDVAIKRIKKICFTSRSSEQERLTIEFWREADILSKLHHPNVV 904 Query: 537 RYYCTERDKQFRYIALE---LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 +Y D +A + +L+ + +K + + + I A G+ +LHS + Sbjct: 905 AFYGVVHDGPGATLATVTEYMVDGSLRHVLLRKDRYLDRRKRLLIAMDAAFGMEYLHSKN 964 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 IVH D+K N+L+++ + + DFGLSK VS GV GT W+APE++ Sbjct: 965 IVHFDLKCDNLLVNLKDPLRPI-CKVGDFGLSKIKRNTLVS----GGVRGTLPWMAPELL 1019 Query: 654 NG--ERTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685 NG + + +D+FS G V + +L+ G+ P+ ++ Sbjct: 1020 NGSSNKVSEKVDVFSFGIVLWEILT-GEEPYANM 1052 >UniRef50_Q54L00 Cluster: Zn binding domain-containing protein; n=1; Dictyostelium discoideum AX4|Rep: Zn binding domain-containing protein - Dictyostelium discoideum AX4 Length = 650 Score = 88.2 bits (209), Expect = 9e-16 Identities = 66/259 (25%), Positives = 124/259 (47%), Gaps = 18/259 (6%) Query: 486 VLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFA----DREVALLRESDA-HAHVVRYY- 539 V+ G G VY+G + RDVA+K E F F DREV ++ D+ H + R+Y Sbjct: 391 VIASGASGK-VYKGIYKGRDVAIKVYSSENFCFNIEEFDREVTIMSLIDSDHPNFTRFYG 449 Query: 540 CTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRD 598 +++K++ + EL S +L+D + K + I + HLHS+ ++HRD Sbjct: 450 ANKQNKKYLFHVSELVKSGSLRDLLLDKEKPLAYFTQLSIASDIANAMKHLHSIGVIHRD 509 Query: 599 VKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERT 658 +K NVL+ T + A + DFG S+ +++ + + + GT +++PE+ G Sbjct: 510 LKSLNVLI-----TEDFTAKVIDFGTSRNVDLAK----QMTLNLGTSCYMSPELFKGNGY 560 Query: 659 TTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILI 718 + D+++ G V + ++++ + P+ ++ +L + P E +IK Sbjct: 561 DETCDVYAFGIVLWEIIAR-KEPYENINSWSIPVLVAKGERPTIPADCPSEYSKLIKACW 619 Query: 719 RAMISAKPSARPPCETILK 737 +PS + C+T+ K Sbjct: 620 TDKPKKRPSFKEICDTLKK 638 >UniRef50_Q229U9 Cluster: Protein kinase domain containing protein; n=4; Oligohymenophorea|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 493 Score = 88.2 bits (209), Expect = 9e-16 Identities = 73/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%) Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILR 580 EV +LR D H H+++ Y +D YI LE+C+ L + +K +F K ++ I+ Sbjct: 95 EVEILRLLD-HPHILKIYEQYQDNNNYYIILEMCTGGELFAKIIEKGSFSEK-EASYIMN 152 Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640 Q + + H+ IVHRD+KP N+LL + S G I D+G SK V + Sbjct: 153 QIVSAVFYAHNHKIVHRDLKPENILLDITS-DGTYNIKIVDWGTSKIFEQDEVMVEK--- 208 Query: 641 VTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFG--DVLRRQANILTGDYN 698 GT +IAPE++ + D++S G + Y +LS G PFG + L AN+ G Y+ Sbjct: 209 -FGTPYYIAPEVLK-KSYNEKCDVWSCGVILYILLS-GTPPFGGKNELEIMANVEKGQYS 265 Query: 699 L--DHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741 L D+L + E K LIR M+ P R +L++ F Sbjct: 266 LEGDNLKHVSEE-----AKDLIRQMLEYNPKNRLSASQVLEHKWF 305 >UniRef50_A0CKT6 Cluster: Chromosome undetermined scaffold_20, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_20, whole genome shotgun sequence - Paramecium tetraurelia Length = 537 Score = 88.2 bits (209), Expect = 9e-16 Identities = 57/202 (28%), Positives = 101/202 (50%), Gaps = 14/202 (6%) Query: 487 LGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQ 546 +G+G G VY+G + +VA+K L A + + E+ H +++++Y Q Sbjct: 17 IGQGAFGQ-VYKGLYKNEEVAIKFLQD-----AQIQETSIMENLQHKNIIKFYQVVYFIQ 70 Query: 547 FRYIALELCSATLQDYV---EKKLNFECKIDSV---EILRQATMGLSHLHSMDIVHRDVK 600 F+Y C + +Y K + +D + +I+ G+ +LHS I+HRD+K Sbjct: 71 FKYFKQGNCQYLVMEYAAGGSLKELMKQSLDELTISQIMESIFTGIEYLHSKQIIHRDIK 130 Query: 601 PHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTT 660 P N+L+ ++ I+DFGLS + + S GT ++APE I + Sbjct: 131 PDNILIKNTEDLSSIK--IADFGLSYQYKPEIRYYQTVSKQCGTFIFMAPEQILNKTYNK 188 Query: 661 SIDIFSLGCVFYYVLSKGQHPF 682 ++D++S G V Y +L++G+HPF Sbjct: 189 AVDMWSCGIVLYMLLNQGKHPF 210 >UniRef50_A0BQ14 Cluster: Chromosome undetermined scaffold_12, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_12, whole genome shotgun sequence - Paramecium tetraurelia Length = 584 Score = 88.2 bits (209), Expect = 9e-16 Identities = 66/223 (29%), Positives = 123/223 (55%), Gaps = 23/223 (10%) Query: 474 MKIGKITFQTDQVLGKGCEGT----FVYRGTFDKRD-VAVKRL----LPECFTFADREVA 524 ++I K T + LGKG GT F +GT D++ +A+K + PE +E+ Sbjct: 6 IQIDKYMIDTQKQLGKGNCGTVYLGFYAKGTGDEKIFLAIKEIPVKASPEVTVSLLQEIN 65 Query: 525 LLRESDAHAHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEIL-RQA 582 +LR+ + H+++V + +++++F Y+ E C+ L D++ LN + V + RQ Sbjct: 66 VLRKIN-HSNIVGFIDAKKNEEFMYLVTEYCNQGALDDFI---LNHNLSEEDVVVFFRQI 121 Query: 583 TMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVT 642 +L S I+HRD+KP N+LL G+V+ ++DFGL+K ++ S + + Sbjct: 122 AAAFKYLVSKKIIHRDIKPQNLLLH----NGQVK--VADFGLAKVMDQSNQS-GKFQTFS 174 Query: 643 GTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685 GT +++P++I E + D++SLG FY++L + ++P+ +V Sbjct: 175 GTPVFMSPQIIKQESYNSLSDMWSLGVTFYFMLFR-EYPWEEV 216 >UniRef50_UPI00004998B6 Cluster: cell division control protein 7; n=1; Entamoeba histolytica HM-1:IMSS|Rep: cell division control protein 7 - Entamoeba histolytica HM-1:IMSS Length = 1760 Score = 87.8 bits (208), Expect = 1e-15 Identities = 74/271 (27%), Positives = 120/271 (44%), Gaps = 20/271 (7%) Query: 478 KITFQTDQVLGKGCEGTFVYRGTFDKRD-VAVKRLL---PECFTFADREVALLRESDAHA 533 K F +G+G G D + VA+K++ E+ LL++ H Sbjct: 417 KSVFSIANSIGRGAYGEVFQGMNADSGEFVAIKQMKVNKKSVMKEVMEEIRLLKKLK-HK 475 Query: 534 HVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 H+VRY + F YI +E + + KK N + S + + Q GL+ +H Sbjct: 476 HIVRYIASTESHGFLYIIMEYMESGSLLNIVKKFNHLNESLSAKYIHQVLDGLAFIHDQG 535 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIG-RVSFSRRSGVTGTDGWIAPEM 652 IVHRD+K N+L++ G V+ I+DFG+S ++N + GT W+APE+ Sbjct: 536 IVHRDIKAANILVAK---DGSVK--IADFGVSVQMNGNEKQEGGSDEDPIGTPNWMAPEV 590 Query: 653 INGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQA--NILTGDYNLDHLDKILPEEE 710 I + TT DI++LGC +++ G P+ D+ A I+ DY P Sbjct: 591 IQMQGTTVKADIWALGCTIIELIT-GNPPYYDLNPTAALYKIVNDDY------PPFPSTV 643 Query: 711 LVVIKILIRAMISAKPSARPPCETILKYPMF 741 V +K + + P+ R +LK+ F Sbjct: 644 SVQLKDFLFSCFKRNPNQRASSRELLKHKWF 674 >UniRef50_A6CBF4 Cluster: Serine/threonine protein kinase; n=1; Planctomyces maris DSM 8797|Rep: Serine/threonine protein kinase - Planctomyces maris DSM 8797 Length = 793 Score = 87.8 bits (208), Expect = 1e-15 Identities = 75/263 (28%), Positives = 125/263 (47%), Gaps = 20/263 (7%) Query: 475 KIGKITFQTDQVLGKGCEGTFVYRG--TFDKRDVAVKRLLPECFT---FADREVALLRES 529 K+GK T +LG+G G VY+ + +RDVA+K L E + DR +A + + Sbjct: 74 KLGKYTISG--LLGQGGMGV-VYKAHDSMIERDVAIKLLPAELASDKMMLDRFLAEAKAA 130 Query: 530 D--AHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLS 587 H HVV + ++ YI +EL + D + + +++ I+ A GL Sbjct: 131 GRLTHPHVVSIHEINQEGDVHYIVMELMTGGSTDDHLESIGPYSPLEASRIIADACEGLM 190 Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647 H+ +VHRD+KP N+L S G ++ ++DFGL+K++ + ++ + GT + Sbjct: 191 VAHASGLVHRDIKPGNLL---QSAHGTIK--VADFGLAKRIIQQSMQLTQDGQLIGTPYF 245 Query: 648 IAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILP 707 ++PE + DI+SLG YY L G HP+ D +I+ Y H D + P Sbjct: 246 MSPEQCESKPVDMRSDIYSLGAT-YYTLLTGDHPYEDA----GSIVQIMYAHCHADILDP 300 Query: 708 EEELVVIKILIRAMISAKPSARP 730 E I A++S + +P Sbjct: 301 REVNSSIPDKCAAIVSKSMAKKP 323 >UniRef50_Q247W3 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 637 Score = 87.8 bits (208), Expect = 1e-15 Identities = 71/231 (30%), Positives = 121/231 (52%), Gaps = 24/231 (10%) Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEI 578 RE+ +L+ D H +V+++Y T +DK++ ++ +E CS L + K+ E K+ V+I Sbjct: 117 RELEILKSLD-HPNVIKFYETYQDKKYFHLVMEYCSGGELLHRIAQDKMASEEKM--VKI 173 Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKL----NIGRVS 634 +++ +G+ +LH I HRD+KP N L S S E++ I DFGLS + N Sbjct: 174 MKKIFLGVKYLHEKGICHRDLKPENFLFSNNSELSEIK--IIDFGLSTYIDEIENEDDNG 231 Query: 635 F--SRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQA-- 690 F + + GT ++APE+I G + DI+SLG + Y++L G+ PF + Sbjct: 232 FFGNDLQTICGTANYLAPEVIKG-KYDKRCDIWSLGVLLYFLLC-GELPFSGNTNTEIFD 289 Query: 691 NILTG--DYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739 IL ++ ++ K+ E + +V K+L+ P R E +LK+P Sbjct: 290 KILNQKVEFQGNNWKKVSKEAKDLVKKLLV-----VNPDDRITLEQVLKHP 335 >UniRef50_A0BPJ3 Cluster: Chromosome undetermined scaffold_12, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_12, whole genome shotgun sequence - Paramecium tetraurelia Length = 414 Score = 87.8 bits (208), Expect = 1e-15 Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 14/213 (6%) Query: 532 HAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHS 591 H ++++ D + LE C D+++ ID ++++ + HLH Sbjct: 165 HPNIIQLEEISCDDNSLSVLLEYCHGG--DFLKYLNQNNNNIDHQLVMKKLLSVVQHLHQ 222 Query: 592 MDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPE 651 +DI+HRD+K NVLL +P+ + +++DFGL+ + ++ + GT G+ APE Sbjct: 223 LDILHRDIKLQNVLLRIPNDVSSL--VLADFGLA--CHKSQIPYYNTR--CGTPGYTAPE 276 Query: 652 MINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANIL---TGDYNLDHLDKILPE 708 + T +DIFS G +F+ +L+ ++PFG Q +L + DY+L HLD I + Sbjct: 277 VFTQAIYDTKVDIFSCGVMFFNLLTL-KNPFGSSRNPQTLLLKNISADYDLTHLDLIKTK 335 Query: 709 EELVVIKILIRAMISAKPSARPPCETILKYPMF 741 L L+ M+ P RP L++P F Sbjct: 336 TPLAY--DLVLQMLHKDPKLRPSATQCLQHPYF 366 >UniRef50_P53350 Cluster: Serine/threonine-protein kinase PLK1; n=42; Bilateria|Rep: Serine/threonine-protein kinase PLK1 - Homo sapiens (Human) Length = 603 Score = 87.8 bits (208), Expect = 1e-15 Identities = 58/216 (26%), Positives = 105/216 (48%), Gaps = 14/216 (6%) Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMG 585 + S AH HVV ++ D F ++ LELC + K+ + ++ LRQ +G Sbjct: 104 IHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLG 163 Query: 586 LSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTD 645 +LH ++HRD+K N+ L+ ++ I DFGL+ K+ R+ + GT Sbjct: 164 CQYLHRNRVIHRDLKLGNLFLNE-----DLEVKIGDFGLATKVEYDG---ERKKTLCGTP 215 Query: 646 GWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKI 705 +IAPE+++ + + +D++S+GC+ Y +L G+ PF ++ + + + Sbjct: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLL-VGKPPFETSCLKETYL-----RIKKNEYS 269 Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741 +P+ V LI+ M+ P+ARP +L F Sbjct: 270 IPKHINPVAASLIQKMLQTDPTARPTINELLNDEFF 305 >UniRef50_P11730 Cluster: Calcium/calmodulin-dependent protein kinase type II gamma chain; n=38; Coelomata|Rep: Calcium/calmodulin-dependent protein kinase type II gamma chain - Rattus norvegicus (Rat) Length = 527 Score = 87.8 bits (208), Expect = 1e-15 Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%) Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589 H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+ Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 127 Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649 H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++ Sbjct: 128 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 182 Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705 PE++ + +DI++ G V Y+L G PF D L +Q D+ D + Sbjct: 183 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241 Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765 PE K LI M++ P+ R + LK+P + C++S + + + VE C F Sbjct: 242 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 294 Query: 766 GAEHPLE 772 A L+ Sbjct: 295 NARRKLK 301 >UniRef50_Q13555 Cluster: Calcium/calmodulin-dependent protein kinase type II gamma chain; n=237; Eumetazoa|Rep: Calcium/calmodulin-dependent protein kinase type II gamma chain - Homo sapiens (Human) Length = 558 Score = 87.8 bits (208), Expect = 1e-15 Identities = 68/247 (27%), Positives = 122/247 (49%), Gaps = 21/247 (8%) Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589 H ++VR + + ++ F Y+ +L + +D V ++ E D+ + Q ++H+ Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHI 127 Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649 H DIVHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++ Sbjct: 128 HQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAW---FGFAGTPGYLS 182 Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705 PE++ + +DI++ G V Y+L G PF D L +Q D+ D + Sbjct: 183 PEVLRKDPYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241 Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765 PE K LI M++ P+ R + LK+P + C++S + + + VE C F Sbjct: 242 TPE-----AKNLINQMLTINPAKRITADQALKHP-WVCQRSTVASMMHRQETVE-CLRKF 294 Query: 766 GAEHPLE 772 A L+ Sbjct: 295 NARRKLK 301 >UniRef50_A0C9W0 Cluster: Chromosome undetermined scaffold_16, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_16, whole genome shotgun sequence - Paramecium tetraurelia Length = 464 Score = 87.4 bits (207), Expect = 2e-15 Identities = 72/266 (27%), Positives = 132/266 (49%), Gaps = 19/266 (7%) Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRDVAVKRL-----LPECFTFADREVALLRESDAHAHV 535 ++ +VLG+G G V + + +AVK++ + + +E+ +L + H ++ Sbjct: 67 WEQGEVLGQGAFGKVVMGLQKNGQIMAVKQVFIQNQIDDKVRQLQKEIEMLSKLQ-HPNI 125 Query: 536 VRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDI 594 VRY E+ QF I LE S ++ +E+ F ++ L+Q +GLS+LH+ ++ Sbjct: 126 VRYMGCEQKNQFINIFLEYVSGGSVSTLLERFGCFRERLIKT-YLKQILLGLSYLHAKNV 184 Query: 595 VHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN 654 +HRD+K N+L+ SG R ++DFG SK+LN ++ + GT ++APE+IN Sbjct: 185 IHRDIKGGNILID-NSG----RCKLADFGSSKQLN--DITHDSIGSICGTPNFMAPEVIN 237 Query: 655 GERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEE-ELVV 713 E+ DI+SLGC ++ GQ P+ + + A + +P++ + Sbjct: 238 QEQYGKKADIWSLGCT-VIEMATGQPPYSEY--KDAIAIMVKIGKSTKPPPIPDQLQSTE 294 Query: 714 IKILIRAMISAKPSARPPCETILKYP 739 K + + P R + +LK+P Sbjct: 295 AKDFLSKCLQIDPKKRATADELLKHP 320 >UniRef50_Q6CVC4 Cluster: Kluyveromyces lactis strain NRRL Y-1140 chromosome B of strain NRRL Y- 1140 of Kluyveromyces lactis; n=2; Saccharomycetaceae|Rep: Kluyveromyces lactis strain NRRL Y-1140 chromosome B of strain NRRL Y- 1140 of Kluyveromyces lactis - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 730 Score = 87.4 bits (207), Expect = 2e-15 Identities = 60/191 (31%), Positives = 98/191 (51%), Gaps = 13/191 (6%) Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEI--- 578 E+ +L+E H ++V YY + ++ I LE V LN D + Sbjct: 518 EMNILKELH-HENIVTYYGSSQEGGNLNIFLEYVPG---GSVSSMLNNYGPFDEPLVKNF 573 Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638 RQ +GL++LH +I+HRD+K N+L+ + G I+DFG+SKKL+ ++R Sbjct: 574 TRQILIGLAYLHKRNIIHRDIKGANILIDIKGGV-----KITDFGISKKLSPLNKQQNKR 628 Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYN 698 + + G+ W+APE++ TT DI+S+GCV + + G+HPF D + QA G Sbjct: 629 ASLQGSVYWMAPEVVKQVVTTEKADIWSVGCVIVEMFT-GKHPFPDFSQMQAIFKIGTNI 687 Query: 699 LDHLDKILPEE 709 + + + EE Sbjct: 688 IPEIPSWVSEE 698 >UniRef50_Q13554 Cluster: Calcium/calmodulin-dependent protein kinase type II beta chain; n=102; Bilateria|Rep: Calcium/calmodulin-dependent protein kinase type II beta chain - Homo sapiens (Human) Length = 664 Score = 87.4 bits (207), Expect = 2e-15 Identities = 68/247 (27%), Positives = 121/247 (48%), Gaps = 21/247 (8%) Query: 532 HAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGLSHL 589 H+++VR + + ++ F Y+ +L + +D V ++ E D+ ++Q + H Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 127 Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649 H M +VHRD+KP N+LL+ V+ ++DFGL+ ++ + ++ G GT G+++ Sbjct: 128 HQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAW---FGFAGTPGYLS 182 Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD----VLRRQANILTGDYNLDHLDKI 705 PE++ E +DI++ G V Y+L G PF D L +Q D+ D + Sbjct: 183 PEVLRKEAYGKPVDIWACG-VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241 Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGF 765 PE K LI M++ P+ R LK+P + C++S + + + VE C F Sbjct: 242 TPE-----AKNLINQMLTINPAKRITAHEALKHP-WVCQRSTVASMMHRQETVE-CLKKF 294 Query: 766 GAEHPLE 772 A L+ Sbjct: 295 NARRKLK 301 >UniRef50_UPI000155511B Cluster: PREDICTED: similar to Calcium/calmodulin-dependent protein kinase ID; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to Calcium/calmodulin-dependent protein kinase ID - Ornithorhynchus anatinus Length = 408 Score = 87.0 bits (206), Expect = 2e-15 Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578 + E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ + Sbjct: 83 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 140 Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638 +RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V Sbjct: 141 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 194 Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696 S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL + Sbjct: 195 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 253 Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739 Y D + D I K IR ++ P+ R CE ++P Sbjct: 254 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 293 >UniRef50_UPI00015A4045 Cluster: Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase).; n=1; Danio rerio|Rep: Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase). - Danio rerio Length = 591 Score = 87.0 bits (206), Expect = 2e-15 Identities = 64/222 (28%), Positives = 105/222 (47%), Gaps = 15/222 (6%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEIL 579 DRE+ L R H H+V++Y DK YI LE CS ++ K + + L Sbjct: 86 DREIELHRALH-HKHIVQFYHHFEDKDNIYILLEYCSRRSLAHILKARKVLTEPEVRYYL 144 Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639 +Q GL +LH +I+HRD+K N ++ + + DFGL+ KL +RR Sbjct: 145 KQIVSGLKYLHEQEILHRDLKLGNFFINE-----FMELKVGDFGLAAKLEPLE---NRRR 196 Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNL 699 + GT +++PE++N + D+++LGCV Y +L G+ PF ++ + Sbjct: 197 TICGTPNYLSPEVLNKQGHGCESDVWALGCVMYTML-LGRPPFETTNLKETYRCIREARY 255 Query: 700 DHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741 + P+ K LI +M++ P RP IL++ F Sbjct: 256 STPSSLSPQ-----AKHLISSMLAKNPVDRPQLCDILRHDFF 292 >UniRef50_Q7UX63 Cluster: Probable serine/threonine-protein kinase pknA; n=1; Pirellula sp.|Rep: Probable serine/threonine-protein kinase pknA - Rhodopirellula baltica Length = 657 Score = 87.0 bits (206), Expect = 2e-15 Identities = 93/335 (27%), Positives = 152/335 (45%), Gaps = 31/335 (9%) Query: 481 FQTDQVLGKGCEGTFVYRGTFDK--RDVAVKRL---LPECFTFA---DREVALLRESDAH 532 +Q + V+G+G G+ VYR K +VAVK + + + F D EV LR H Sbjct: 29 YQIESVIGRGGMGS-VYRAKHAKSGEEVAVKLIAQHVADDMRFRRRFDAEVETLRRL-RH 86 Query: 533 AHVVRYYCTERDKQFRYIALELCSA-TLQDYVE--KKLNFECKIDSVEILRQATMGLSHL 589 +VR + + ++EL TLQ + K+L + + +++I Q L H Sbjct: 87 PGIVRLIGYGEEAGQLFYSMELVRGETLQKRIRDVKRLGW---LPTLDIASQVCSALKHA 143 Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649 H + ++HRD+KP N++L + GEV+ + DFG++K G + V GT ++A Sbjct: 144 HDIGVIHRDLKPANLIL---TDAGEVK--LVDFGIAKLFGFGEQTL--HGSVLGTADYMA 196 Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQANILTGDYNLDHLDKILPE 708 PE T D+++LG V Y +L+ G+ PF G + + L D + LD I P+ Sbjct: 197 PEQAGSHSITPRTDLYALGSVMYAMLA-GRAPFAGKKVTQVVEALQRDRPVP-LDLINPD 254 Query: 709 EELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACG---F 765 V++I + ++ P+ RPP + ++ L + +++Q G F Sbjct: 255 IPAEVVEI-VHQLLEKDPADRPP-TALAVMNRLKATRAGLQRGRTLNEQASRTQLGDEDF 312 Query: 766 GAEHPLERGGARVLRGDWRVRVCRVVAGDLRTRRT 800 E P G RG R V+ DL T T Sbjct: 313 TPELPPNLAGDLDTRGHHHTDASREVSPDLPTNET 347 >UniRef50_Q5WFL0 Cluster: Serine/threonine protein kinase; n=1; Bacillus clausii KSM-K16|Rep: Serine/threonine protein kinase - Bacillus clausii (strain KSM-K16) Length = 706 Score = 87.0 bits (206), Expect = 2e-15 Identities = 65/217 (29%), Positives = 108/217 (49%), Gaps = 16/217 (7%) Query: 475 KIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLP-----ECFTFADREVALLRES 529 +IG D + G G ++ R VAVK L P E F R A S Sbjct: 5 RIGGRYVVLDSIGGGGMANVYLALDVILDRHVAVKVLQPQFSEDEQFINRFRREAQAATS 64 Query: 530 DAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSH 588 A+ ++V Y + YI +E TL+ ++++ + + +++ +Q G+ H Sbjct: 65 LANPNIVNIYDVGEEDNVYYIVMEYVRGRTLKQVIQEEGPLDIAV-ALDYFKQILYGVGH 123 Query: 589 LHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWI 648 H+M IVHRD+KP N+L+ S GE A ++DFG+++ + ++ + + V G+ ++ Sbjct: 124 AHAMQIVHRDIKPQNILI---SENGE--AKVTDFGIARAMTSATITHT--NSVMGSVHYL 176 Query: 649 APEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GD 684 +PE G T DI+SLG V Y +++ GQ PF GD Sbjct: 177 SPEQARGGHVTYRSDIYSLGIVLYEMVT-GQIPFSGD 212 >UniRef50_A7Q6K4 Cluster: Chromosome chr11 scaffold_56, whole genome shotgun sequence; n=40; Eukaryota|Rep: Chromosome chr11 scaffold_56, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 1063 Score = 87.0 bits (206), Expect = 2e-15 Identities = 81/259 (31%), Positives = 127/259 (49%), Gaps = 25/259 (9%) Query: 487 LGKGCEGTFVYRGTFDKRDVAVKRLLPECFTF--ADRE--------VALLRESDAHAHVV 536 LG G G VY G + DVA+KR+ CF ++RE AL+ S H +VV Sbjct: 796 LGSGTYGA-VYHGKWKGSDVAIKRIKASCFAGRPSERERLIADFWKEALILSSLHHPNVV 854 Query: 537 RYYCTERDKQFRYIALE---LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 +Y RD +A + + +L+ +++KK + I A+ G+ +LH + Sbjct: 855 SFYGIVRDGPGGSLATVTEFMVNGSLKQFLQKKDRTIDRRKRRIIAMDASFGMEYLHGKN 914 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 IVH D+K N+L++M V I D GLSK VS GV GT W+APE++ Sbjct: 915 IVHFDLKCENLLVNMRDPHRPV-CKIGDLGLSKVKQHTLVS----GGVRGTLPWMAPELL 969 Query: 654 NGE--RTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEEL 711 +G+ T ID++S G V + +L+ G P+ D+ A+I+ G N + L +P Sbjct: 970 SGKTNMVTEKIDVYSFGIVMWELLT-GDEPYADM--HCASIIGGIVN-NTLRPQIPRWCE 1025 Query: 712 VVIKILIRAMISAKPSARP 730 K L+ + ++ P+ RP Sbjct: 1026 PEWKYLMESCWASDPAERP 1044 >UniRef50_Q54L02 Cluster: LIM domain-containing protein; n=1; Dictyostelium discoideum AX4|Rep: LIM domain-containing protein - Dictyostelium discoideum AX4 Length = 874 Score = 87.0 bits (206), Expect = 2e-15 Identities = 65/259 (25%), Positives = 124/259 (47%), Gaps = 18/259 (6%) Query: 486 VLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFA----DREVALLRESDA-HAHVVRYY- 539 V+ G G VY+G + RDVA+K E F F DREV ++ D+ H + R+Y Sbjct: 615 VIAAGASGK-VYKGIYKGRDVAIKVYSSENFCFNIDEFDREVTIMSLIDSDHPNFTRFYG 673 Query: 540 CTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRD 598 +++K++ + EL S +L+D + K + I + HLHS+ ++HRD Sbjct: 674 ANKQNKKYLFHVSELVKSGSLRDLLLDKEKPLLYFTQLSIASDIANAMKHLHSIGVIHRD 733 Query: 599 VKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERT 658 +K NVL+ T + A + DFG S+ +++ + + GT +++PE+ G Sbjct: 734 LKSLNVLI-----TEDFTAKVIDFGTSRNVDLAK----HMTMNLGTSCYMSPELFKGNGY 784 Query: 659 TTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILI 718 + D+++ G V + ++++ + P+ ++ ++ + + P E +IK Sbjct: 785 DETCDVYAFGIVLWEIIAR-KEPYENINSWSIPVMVAKGDRPTIPADCPSEYSKLIKACW 843 Query: 719 RAMISAKPSARPPCETILK 737 +PS + C+T+ K Sbjct: 844 TDKPKKRPSFKEICDTLKK 862 >UniRef50_O44997 Cluster: Dap (Death-associated protein) kinase homolog protein 1; n=3; Bilateria|Rep: Dap (Death-associated protein) kinase homolog protein 1 - Caenorhabditis elegans Length = 1425 Score = 87.0 bits (206), Expect = 2e-15 Identities = 56/168 (33%), Positives = 93/168 (55%), Gaps = 13/168 (7%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFEC--KIDSV 576 +REV +L++ +++VV + I LEL S L D+V K EC ++++ Sbjct: 77 EREVRVLQKIRGNSNVVELHAVYETASDVIIVLELVSGGELFDHVCAK---ECLDEVEAA 133 Query: 577 EILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS 636 ++Q + + HLHS+ IVH D+KP NV+L G+ + I DFGLS+++ G V Sbjct: 134 AFIKQILLAVRHLHSLHIVHLDIKPENVMLKQ---RGDSQIKIIDFGLSREIEPGAVV-- 188 Query: 637 RRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD 684 + GT ++APE++N E + + D++++G V Y +LS G GD Sbjct: 189 --KDMVGTPEFVAPEVVNYEALSPATDMWAVGVVTYILLSGGSPFLGD 234 >UniRef50_Q2H8Z5 Cluster: Putative uncharacterized protein; n=2; Sordariomycetes|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 865 Score = 87.0 bits (206), Expect = 2e-15 Identities = 64/178 (35%), Positives = 97/178 (54%), Gaps = 18/178 (10%) Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEI-- 578 RE++LLR+ H ++V+Y ++ I LE + V+ LN + I Sbjct: 646 REISLLRDL-RHPNIVQYLGCGSSVEYLNIFLEYVAG---GSVQTMLNSYGALPEPLIRS 701 Query: 579 -LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKL---NI--GR 632 +RQ GLS+LH+ DI+HRD+K N+L+ G ++ ISDFG+SKKL NI G Sbjct: 702 FVRQILNGLSYLHNRDIIHRDIKGANILV---DNKGTIK--ISDFGISKKLEATNILNGA 756 Query: 633 VSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQA 690 + R + G+ W+APE++ T DI+SLGC+ +++ GQHPF D + QA Sbjct: 757 NNNKHRPSLQGSVFWMAPEVVKQTSYTRKADIWSLGCLVVEMMT-GQHPFPDCTQLQA 813 >UniRef50_Q696W0 Cluster: Striated muscle preferentially expressed protein kinase; n=7; Danio rerio|Rep: Striated muscle preferentially expressed protein kinase - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 2995 Score = 87.0 bits (206), Expect = 2e-15 Identities = 67/226 (29%), Positives = 111/226 (49%), Gaps = 14/226 (6%) Query: 517 TFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNF-ECKIDS 575 T A RE+ALL E D H +VR++ ++ I ELC L + + K+ E ++ S Sbjct: 1293 TCALRELALLAELD-HKSIVRFHDAFEKRRVVIILTELCHEELLERITKRTTILESEVQS 1351 Query: 576 VEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSF 635 I+RQ G+ +LH DI+H D+KP N+L++ T ++R I DFG + K+ + Sbjct: 1352 --IIRQLLEGIEYLHQNDIIHLDLKPENILMA-DQKTDQIR--ICDFGNALKVKPNEELY 1406 Query: 636 SRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTG 695 + G +IAPE++N + S DI+ +G + Y L+ G PF R + Sbjct: 1407 CK----YGIPEFIAPEIVNQSPISKSTDIWPVGVITYLCLT-GVSPFAGENDRDTLLNIR 1461 Query: 696 DYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741 +YN+ + + + +I+ ++S K RP L +P F Sbjct: 1462 NYNVAFEESMFKDLCREAKGFIIKVLVSNK--LRPDATECLLHPWF 1505 Score = 70.1 bits (164), Expect = 3e-10 Identities = 61/209 (29%), Positives = 100/209 (47%), Gaps = 18/209 (8%) Query: 548 RYIAL--ELCSAT--LQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHN 603 RY+ L E CS LQ+ +++ E D V + Q GL +LH+ I+H D+KP N Sbjct: 2749 RYLVLITEYCSGKEILQNLIDRFCYSED--DVVGFIVQILQGLEYLHNCKILHLDIKPDN 2806 Query: 604 VLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSID 663 +++ T I DFG +++ N +S + S GT ++APEM+ G+ D Sbjct: 2807 IMV-----TNLNVIKIIDFGSAQRFN--PLSLQQCSRYLGTLEYMAPEMLKGDLVGPPAD 2859 Query: 664 IFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMIS 723 I+SLG + Y +LS G+HPF D + + D K+ P+ ++ +++ Sbjct: 2860 IWSLGVLSYIMLS-GRHPFEDKDPQLTEAKIHEAKFDS-TKLYPKVSQSA-STFLKKILN 2916 Query: 724 AKPSARPPCETILKYPMFWCKQSILNFLQ 752 + P RP + L + W S L L+ Sbjct: 2917 SYPWCRPTIKDCLNHS--WLHDSYLKKLR 2943 >UniRef50_Q8IU85 Cluster: Calcium/calmodulin-dependent protein kinase type 1D; n=114; Eumetazoa|Rep: Calcium/calmodulin-dependent protein kinase type 1D - Homo sapiens (Human) Length = 385 Score = 87.0 bits (206), Expect = 2e-15 Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 19/225 (8%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578 + E+A+LR+ H ++V Y+ ++L S L D + +K F + D+ + Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTL 124 Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638 +RQ + +LH M IVHRD+KP N+L S E + MISDFGLSK G V Sbjct: 125 IRQVLDAVYYLHRMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----M 178 Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGD 696 S GT G++APE++ + + ++D +S+G V Y+L G PF D + IL + Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAE 237 Query: 697 YNLD--HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739 Y D + D I K IR ++ P+ R CE ++P Sbjct: 238 YEFDSPYWDDISDS-----AKDFIRNLMEKDPNKRYTCEQAARHP 277 >UniRef50_UPI00004990CF Cluster: protein kinase; n=1; Entamoeba histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba histolytica HM-1:IMSS Length = 446 Score = 86.6 bits (205), Expect = 3e-15 Identities = 66/223 (29%), Positives = 111/223 (49%), Gaps = 16/223 (7%) Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEIL 579 RE+ ++R+ H +VV+ Y D++ + +E S L D + ++ +F + D+ +I+ Sbjct: 196 REIDVMRKLSNHPNVVKLYDVYEDEKTILMVIEYMSGGELYDQIIQRGSFT-EADASDIV 254 Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639 Q L ++HS I HRD+KP N+L + P G I+DFGLSK + G + + Sbjct: 255 YQILSALCYIHSNGIGHRDLKPENLLCATPKGD---IVKIADFGLSKDNSDGNTAMTT-- 309 Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDY 697 G+ ++APE++ G DI+SLG V YVL G PF + + I++GDY Sbjct: 310 -CCGSPSYVAPEVLEGSSYDHECDIWSLG-VITYVLLSGYLPFFGETQDELFQKIMSGDY 367 Query: 698 NLDH-LDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739 ++ K + EE K I + P R ++++P Sbjct: 368 TFNYSCFKGVSEE----AKDFINKCLVVDPQERATAAQLMEHP 406 >UniRef50_Q4RSE0 Cluster: Chromosome 13 SCAF15000, whole genome shotgun sequence; n=2; Euteleostomi|Rep: Chromosome 13 SCAF15000, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 414 Score = 86.6 bits (205), Expect = 3e-15 Identities = 64/193 (33%), Positives = 97/193 (50%), Gaps = 17/193 (8%) Query: 551 ALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPS 610 A + L D + +K F ++D+ ++RQ +++LHSM IVHRD+KP N+L P Sbjct: 130 AARVSGGELFDRIVEK-GFYTEMDASRLIRQVLDAVNYLHSMGIVHRDLKPENLLYFSPD 188 Query: 611 GTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCV 670 E + MISDFGLSK G V + GT G++APE++ + + ++D +S+G V Sbjct: 189 --DESKIMISDFGLSKMEGTGDV----MATACGTPGYVAPEVLAQKPYSKAVDCWSIG-V 241 Query: 671 FYYVLSKGQHPFGDV--LRRQANILTGDYNLD--HLDKILPEEELVVIKILIRAMISAKP 726 Y+L G PF D + IL DY D + D I K I ++ P Sbjct: 242 IAYILLCGYPPFYDENDSKLFEQILKADYEFDAPYWDDISDS-----AKDFISRLMEKNP 296 Query: 727 SARPPCETILKYP 739 R C+ L++P Sbjct: 297 EKRFTCDQALQHP 309 >UniRef50_Q5Z1J1 Cluster: Putative serine/threonine protein kinase; n=2; Bacteria|Rep: Putative serine/threonine protein kinase - Nocardia farcinica Length = 526 Score = 86.6 bits (205), Expect = 3e-15 Identities = 62/209 (29%), Positives = 101/209 (48%), Gaps = 9/209 (4%) Query: 481 FQTDQVLGKGCEGT-FVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----HAH 534 ++ QVLG G GT ++ + R A+K L + T + RE++ H + Sbjct: 12 YRVIQVLGSGGMGTVYLAQNPILPRRDALKVLSADLSTDDEFRARFEREANLAAGLDHPN 71 Query: 535 VVRYYCTERDKQFRYIALELCSAT-LQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 +V Y + +IA++ T + K + ++ I+ + GL + H Sbjct: 72 IVAVYNRGEEDGQLWIAMQYVDGTDAAEEAAKGPSVMTPQRALRIVSEVGKGLDYAHRRG 131 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 ++HRDVKP N LLS G E R +++DFG++K G+ + T + +PE + Sbjct: 132 LLHRDVKPANFLLSAVDGDDEERVLLTDFGVAKSAEDGQ-DLTATGNFMATVAYASPEQL 190 Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 GER DI+SLGC FY +L+ GQ+PF Sbjct: 191 LGERLDHRSDIYSLGCSFYRMLT-GQNPF 218 >UniRef50_Q1EW82 Cluster: Protein kinase:PASTA:Serine/threonine protein kinase, active site; n=2; Clostridiaceae|Rep: Protein kinase:PASTA:Serine/threonine protein kinase, active site - Clostridium oremlandii OhILAs Length = 651 Score = 86.6 bits (205), Expect = 3e-15 Identities = 79/280 (28%), Positives = 133/280 (47%), Gaps = 31/280 (11%) Query: 476 IGKITFQTDQVLGK--GCEGTFVYRG--TFDKRDVAVKRLLPECFTFADREVALLRESDA 531 IGK+ + +++ K G VY+ R VA+K L PE D +ES A Sbjct: 2 IGKVLGKRYEIIEKIGGGGMAIVYKAKCALLNRFVAIKVLRPEFINDKDLLDKFRKESQA 61 Query: 532 -----HAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMG 585 H ++V Y + YI +E + TL++ +++K K + ++ RQ + Sbjct: 62 AASLSHPNIVNVYDVGEEDDIYYIVMEYVNGKTLKEVIKEKGKLN-KDEILDFTRQIALA 120 Query: 586 LSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTD 645 L H H+ +VHRD+KPHN+L+ T + RA ++DFG++ L + + + G+ Sbjct: 121 LKHAHANHVVHRDIKPHNILI-----TEDHRAKVTDFGIA--LAATSSTITNTGSIIGSV 173 Query: 646 GWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GD-----VLRR-QAN-ILTGDY 697 + +PE G T D++SLG V Y ++ G+ PF GD L+ Q N L Y Sbjct: 174 HYFSPEQARGGYTDEKSDLYSLGIVM-YEMATGRLPFEGDAPITIALKHIQENPELPSQY 232 Query: 698 NLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILK 737 N I + E++++K+L + I+ +A E + K Sbjct: 233 N----PSISKDLEIIIMKLLQKEQINRYANAAALIEDLYK 268 >UniRef50_Q9LRY7 Cluster: Similarity to protein kinase; n=3; Arabidopsis thaliana|Rep: Similarity to protein kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 1117 Score = 86.6 bits (205), Expect = 3e-15 Identities = 78/260 (30%), Positives = 119/260 (45%), Gaps = 25/260 (9%) Query: 487 LGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALL-----RESDA-----HAHVV 536 LG G GT VY GT+ DVA+KR+ CF E L RE+ H +VV Sbjct: 842 LGSGTYGT-VYHGTWRGTDVAIKRIRNSCFAGRSSEQERLTKDFWREAQILSNLHHPNVV 900 Query: 537 RYYCTERDKQFRYIALE---LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 +Y D +A + + +L+ + KK + I A G+ +LHS + Sbjct: 901 AFYGIVPDGTGGTLATVTEFMVNGSLRHALLKKDRLLDTRKKIIIAMDAAFGMEYLHSKN 960 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 IVH D+K N+L+++ + + D GLS+ VS GV GT W+APE++ Sbjct: 961 IVHFDLKCENLLVNLRDPQRPI-CKVGDLGLSRIKRNTLVS----GGVRGTLPWMAPELL 1015 Query: 654 NGERTTTS--IDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEEL 711 NG T S +D+FS G + +L+ G+ P+ D+ + G + L +P+ Sbjct: 1016 NGSSTRVSEKVDVFSYGISLWEILT-GEEPYADM---HCGAIIGGIVKNTLRPPIPKSCS 1071 Query: 712 VVIKILIRAMISAKPSARPP 731 K L+ S P +RPP Sbjct: 1072 PEWKKLMEQCWSVDPDSRPP 1091 >UniRef50_A0C4R4 Cluster: Chromosome undetermined scaffold_15, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_15, whole genome shotgun sequence - Paramecium tetraurelia Length = 491 Score = 86.6 bits (205), Expect = 3e-15 Identities = 64/247 (25%), Positives = 121/247 (48%), Gaps = 19/247 (7%) Query: 506 VAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEK 565 VA+K L + + A +E+ ++R+ H +++ Y DK+F I +EL +++ ++ Sbjct: 149 VALKNLNVDNVSVA-KEIQIMRQLK-HPGIIKIYEVYEDKEFICIVMELMQYSMKQQKKR 206 Query: 566 KLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLS 625 +C +I+ Q M L ++H I+HRD+KP N+L + I DFGL+ Sbjct: 207 HTEHQC----AQIMLQLFMVLQYIHDRKIIHRDIKPDNILYK-----NQDTICICDFGLA 257 Query: 626 KKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV 685 N V +R GT G++APE++ ++ +D++S G + Y +L G+ PF Sbjct: 258 DYYNPMSVYQYQR---CGTPGYVAPEVLRDQKYDFKVDVYSAGIILYTLL-VGKQPF--A 311 Query: 686 LRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQ 745 Q ++ +Y+ +D + + + L ++++S P ARP +L + F+ Sbjct: 312 AHSQNKVVQLNYH-GKIDYAQVKASDLCLSFL-KSVLSINPQARPSAYEVLHHEWFFKTL 369 Query: 746 SILNFLQ 752 N+ Q Sbjct: 370 GESNYFQ 376 >UniRef50_A0LLB3 Cluster: Serine/threonine protein kinase with TPR repeats; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Serine/threonine protein kinase with TPR repeats - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 850 Score = 86.2 bits (204), Expect = 4e-15 Identities = 79/269 (29%), Positives = 134/269 (49%), Gaps = 36/269 (13%) Query: 481 FQTDQVLGKGCEGTFVYRGTFDK---RDVAVKRLLPECFT-------FADREVA---LLR 527 F+ DQ L +G G V+R FD R VA+K L+P+ A RE A L++ Sbjct: 15 FRLDQYLARGAMG-LVFRA-FDTVLVRTVALK-LIPKAIEEGLSKEELAAREEARKRLIQ 71 Query: 528 ESDA-----HAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQA 582 E+ A H ++V + ++F YI +E + ++ ++ D++ I+ Q Sbjct: 72 EAKAAGRLTHPNIVTIHSYGESEEFEYICMEFVTGETLAHMLRERKAVPIEDAIPIVEQI 131 Query: 583 TMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVT 642 + L + IVHRD+KP NV++++ + R + DFG++K + +S + V Sbjct: 132 LLALQTANQEKIVHRDIKPSNVMVTL-----DKRVKVMDFGIAK---LPSLSMTITGTVL 183 Query: 643 GTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHL 702 GT +++PE I+G++ DIFSLG VFY +L+ G+ PF N T Y + + Sbjct: 184 GTPYYMSPEQISGQKVDIRSDIFSLGAVFYEMLT-GERPF-----EAENTATLAYKIVQV 237 Query: 703 DKILPEEELVVIKILIRAMISAKPSARPP 731 + I P+ + I + ++IS K A+ P Sbjct: 238 EPIPPKVLNIHIPSTVGSIIS-KALAKDP 265 >UniRef50_A7RQY7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 676 Score = 86.2 bits (204), Expect = 4e-15 Identities = 80/293 (27%), Positives = 141/293 (48%), Gaps = 32/293 (10%) Query: 481 FQTDQVLGKGCEGT-FVYRGTFDKRDVAVKRLLPECFTFADREVAL----LRESDAHAHV 535 ++ +++G+G GT ++ R D V +K++ E T +R+ AL + H ++ Sbjct: 4 YEKVRIVGRGAYGTVYLCRRLVDNFLVIIKQIPVEEMTKEERQSALNEVKVLSMFQHPNI 63 Query: 536 VRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILR---QATMGLSHLHS 591 +RYY + ++ I +E T+ DY++++ +D EILR Q + L H+H Sbjct: 64 IRYYDSFVQEKALMIVMEYAQGGTIYDYLQQRGGK--LMDEDEILRLFVQILLALRHVHK 121 Query: 592 MDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPE 651 I+HRD+K N+LL+ I DFG+SK L+ S S+ + V G+ +I+PE Sbjct: 122 GQILHRDLKTQNILLNKKRKV----VKIGDFGISKILS----SKSKANTVIGSPCYISPE 173 Query: 652 MINGERTTTSIDIFSLGCVFYYVLS-KGQHPFGDVLRRQANILTGDYNLDHLDKILPEEE 710 + G+ D++SLGCV Y + + K ++ I+ G ++ +PE Sbjct: 174 LCEGKPYNQKSDVWSLGCVLYELTTLKRAFEASNLPALVLKIMRGYFS------PIPERY 227 Query: 711 LVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCAC 763 ++ LI M+ P+ RP + I+ P+ I+N L D+ V C Sbjct: 228 SEELRKLILDMLVLDPTKRPGIKEIMAQPV------IVNALFDLPTDVGRVPC 274 >UniRef50_Q20845 Cluster: Serine/threonine-protein kinase plk-3; n=1; Caenorhabditis elegans|Rep: Serine/threonine-protein kinase plk-3 - Caenorhabditis elegans Length = 615 Score = 86.2 bits (204), Expect = 4e-15 Identities = 63/216 (29%), Positives = 105/216 (48%), Gaps = 16/216 (7%) Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILR 580 REV + R+ +H ++V+++ D Q Y LELCS + K+ + ++ Sbjct: 82 REVEIHRQL-SHRNIVQFHHFFEDSQNVYFTLELCSKNSLMELNKQRGPLTEHEARFYTI 140 Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640 Q G+ HLH++ I+HRD+K N+ L+ ++ I DFGL+ +R Sbjct: 141 QVAEGVKHLHNLQIIHRDLKLGNLFLNE-----HLQVKIGDFGLATFCEKNEKKMTRG-- 193 Query: 641 VTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLD 700 GT +IAPE++N +DI+++GC+ YVL G PF + R Q + + Sbjct: 194 --GTPNYIAPEVLNETGHAFEVDIWAIGCIL-YVLLFGSPPF-ESRRVQETYV----RIK 245 Query: 701 HLDKILPEEELVVIKILIRAMISAKPSARPPCETIL 736 + D ++PE LIR+++ P RP E +L Sbjct: 246 NNDYVVPENASPTANRLIRSLLDPVPDRRPTAEAVL 281 >UniRef50_UPI000069FC64 Cluster: Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (NimA-related protein kinase 5).; n=1; Xenopus tropicalis|Rep: Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (NimA-related protein kinase 5). - Xenopus tropicalis Length = 672 Score = 85.8 bits (203), Expect = 5e-15 Identities = 69/264 (26%), Positives = 123/264 (46%), Gaps = 23/264 (8%) Query: 485 QVLGKGCEG-TFVYRGTFDKRDVAVKRL----LPECFTFADREVALLRESDAHAHVVRYY 539 +++G+G G ++ +G D +K + +P A + +L H ++V ++ Sbjct: 8 RMIGEGAFGKAYLAKGKSDNMQCVIKEINLSKMPTKEKEASHKEVVLLAKMKHPNIVTFF 67 Query: 540 CTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSV-EILRQATMGLSHLHSMDIVHR 597 + ++ YI +E C L V K+ + D + Q ++GL H+H ++HR Sbjct: 68 SSIEERNKLYIVMEYCDGGDLMKRVNKQRGVLFEEDQILSWFVQISLGLKHIHDRKVLHR 127 Query: 598 DVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGER 657 D+K N+ LS +GT A + DFG+++ LN + +R GT +++PE+ + Sbjct: 128 DIKAQNIFLS-NNGT---LAKLGDFGIARMLN-NTMELART--CVGTPYYLSPEICENKP 180 Query: 658 TTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDHLDKILPEEELVVIK 715 DI+SLGCV Y + + +HPF RQ I G Y + +P + ++ Sbjct: 181 YNNKTDIWSLGCVLYELCAL-KHPFEASSLRQLVLKICRGRY------EPIPTKYSYDLR 233 Query: 716 ILIRAMISAKPSARPPCETILKYP 739 IL+ + RP +ILK P Sbjct: 234 ILVSQLFKISSRDRPSINSILKKP 257 >UniRef50_UPI000069FC63 Cluster: Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (NimA-related protein kinase 5).; n=1; Xenopus tropicalis|Rep: Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (NimA-related protein kinase 5). - Xenopus tropicalis Length = 624 Score = 85.8 bits (203), Expect = 5e-15 Identities = 69/264 (26%), Positives = 123/264 (46%), Gaps = 23/264 (8%) Query: 485 QVLGKGCEG-TFVYRGTFDKRDVAVKRL----LPECFTFADREVALLRESDAHAHVVRYY 539 +++G+G G ++ +G D +K + +P A + +L H ++V ++ Sbjct: 8 RMIGEGAFGKAYLAKGKSDNMQCVIKEINLSKMPTKEKEASHKEVVLLAKMKHPNIVTFF 67 Query: 540 CTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSV-EILRQATMGLSHLHSMDIVHR 597 + ++ YI +E C L V K+ + D + Q ++GL H+H ++HR Sbjct: 68 SSIEERNKLYIVMEYCDGGDLMKRVNKQRGVLFEEDQILSWFVQISLGLKHIHDRKVLHR 127 Query: 598 DVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGER 657 D+K N+ LS +GT A + DFG+++ LN + +R GT +++PE+ + Sbjct: 128 DIKAQNIFLS-NNGT---LAKLGDFGIARMLN-NTMELART--CVGTPYYLSPEICENKP 180 Query: 658 TTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDHLDKILPEEELVVIK 715 DI+SLGCV Y + + +HPF RQ I G Y + +P + ++ Sbjct: 181 YNNKTDIWSLGCVLYELCAL-KHPFEASSLRQLVLKICRGRY------EPIPTKYSYDLR 233 Query: 716 ILIRAMISAKPSARPPCETILKYP 739 IL+ + RP +ILK P Sbjct: 234 ILVSQLFKISSRDRPSINSILKKP 257 >UniRef50_A6GFX5 Cluster: Serine/threonine protein kinase; n=1; Plesiocystis pacifica SIR-1|Rep: Serine/threonine protein kinase - Plesiocystis pacifica SIR-1 Length = 345 Score = 85.8 bits (203), Expect = 5e-15 Identities = 71/215 (33%), Positives = 107/215 (49%), Gaps = 17/215 (7%) Query: 475 KIGKITFQTDQVLGKGCEGTFVYRGTFDK--RDVAVKRLLPECFTFADREVALLRESDA- 531 KIG Q +LGKG G VY G R VA+K L + + + LRE + Sbjct: 7 KIGHYDIQG--LLGKGAMGE-VYEGLDPNLNRRVALKVLGRKHQESTEFKERFLREGRSL 63 Query: 532 ----HAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLS 587 H +VV+ Y ++A+E + KK D+ E++RQA +GLS Sbjct: 64 ASMNHVNVVQVYFIGEFDGRPFLAMEFLDGNDIGGLIKKNGPLHPGDAAEVVRQAAVGLS 123 Query: 588 HLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGW 647 +VHRDVKP N+++ + TGEV+ ++DFGL+K L +S + GT + Sbjct: 124 EAKRAGVVHRDVKPSNLVV---TSTGEVK--VTDFGLAKALQ-EDLSITATGVFVGTPDY 177 Query: 648 IAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 +APE GE +S D+++LGC Y++ + G PF Sbjct: 178 LAPEQAMGEEVDSSADVYALGCSLYHMCT-GNPPF 211 >UniRef50_Q57VI0 Cluster: Polo-like protein kinase; n=3; Trypanosoma brucei|Rep: Polo-like protein kinase - Trypanosoma brucei Length = 768 Score = 85.8 bits (203), Expect = 5e-15 Identities = 66/216 (30%), Positives = 105/216 (48%), Gaps = 22/216 (10%) Query: 532 HAHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLH 590 H H+V + T D YI LE CS TL + ++++ F ++ I Q+ + ++H Sbjct: 98 HKHIVNFIRTFHDDWNVYILLEKCSNQTLMEILKRRQRFSVP-ETQYIALQSLSAIQYMH 156 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650 ++HRD+K N+++ + I DFGL+ +L + R+ + GT +IAP Sbjct: 157 EQCVIHRDLKLGNIMMD-----ANMNVKIGDFGLAAEL---QYDGERKRTICGTPNYIAP 208 Query: 651 EMINGERTTTS--IDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNL-DHLDKI 705 E+I G R S +D++SLG V Y L G+ PF DV I Y H+D Sbjct: 209 EIIEGSREGHSYEVDVWSLG-VILYTLLVGEPPFQTSDVKATYRRIRQCRYEFPSHVD-- 265 Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741 +PE K LI +++ ++P RP I +P F Sbjct: 266 VPESG----KELIHSILQSRPDQRPTLLEIRSHPFF 297 >UniRef50_A7AUM8 Cluster: Ser/Thr protein kinase, putative; n=1; Babesia bovis|Rep: Ser/Thr protein kinase, putative - Babesia bovis Length = 1106 Score = 85.8 bits (203), Expect = 5e-15 Identities = 62/216 (28%), Positives = 114/216 (52%), Gaps = 18/216 (8%) Query: 533 AHVVRYYCTERDKQFRYIALELCSA-TLQDYV-EKKLNFECKIDSVEILRQATMGLSHLH 590 AH R + ER ++ +I +E C+ L + + +++L+ + ++ +E+ RQ LS++H Sbjct: 367 AHHARKH-KERPVKYLFILMEYCAEDNLANAINDRRLHDKPQL-VIELFRQILEALSYIH 424 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVS-FSRRSGVTGTDGWIA 649 I+HRD+KP N+ L G ++ + DFGL+ KLN G S F+ +G+ GT +++ Sbjct: 425 EKGIIHRDIKPSNIFLKSEDGVLSIK--LGDFGLTAKLNTGPSSDFTNPTGIVGTLHYMS 482 Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEE 709 PE G+ +DIF+ G V + +LS PF + R A++L+ + +K P E Sbjct: 483 PEQERGDSYDEKVDIFAAGVVLFEMLSP---PFTTNMER-ADVLS---SFPTEEKKWPSE 535 Query: 710 ELVVIK----ILIRAMISAKPSARPPCETILKYPMF 741 + + ++ +M+ P RP +L+ +F Sbjct: 536 FVSTVDHGIFKILESMLCIDPMKRPSASYLLQSEVF 571 >UniRef50_Q6FXI1 Cluster: Candida glabrata strain CBS138 chromosome B complete sequence; n=1; Candida glabrata|Rep: Candida glabrata strain CBS138 chromosome B complete sequence - Candida glabrata (Yeast) (Torulopsis glabrata) Length = 676 Score = 85.8 bits (203), Expect = 5e-15 Identities = 55/171 (32%), Positives = 99/171 (57%), Gaps = 10/171 (5%) Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILR 580 E++LL+E H ++V YY + ++ I LE ++ + FE + V R Sbjct: 462 EMSLLKELQ-HENIVTYYGSSQEGGNLNIFLEYVPGGSVSSMLSNYGPFEEPL-IVNFTR 519 Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLN-IGRVSFSRRS 639 Q +G+++LH +I+HRD+K N+L+ + G V+ I+DFG+SKKL+ + + + +R+ Sbjct: 520 QILIGVAYLHRKNIIHRDIKGANILIDI---KGCVK--ITDFGISKKLSPLNQENQDKRT 574 Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQA 690 + G+ W++PE++ TT+ DI+S GCV + + G+HP+ D + QA Sbjct: 575 SLQGSVYWMSPEVVKQTATTSKADIWSTGCVVIEMFT-GKHPYPDFSQMQA 624 >UniRef50_Q6L2T2 Cluster: Serine/threonine protein kinase; n=1; Picrophilus torridus|Rep: Serine/threonine protein kinase - Picrophilus torridus Length = 1205 Score = 85.8 bits (203), Expect = 5e-15 Identities = 61/214 (28%), Positives = 111/214 (51%), Gaps = 20/214 (9%) Query: 477 GKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVA-LLRESD----- 530 G + + LG+G +G VY+ + + V L + + D + ++RE++ Sbjct: 6 GNNRYSVIKKLGEGGKG-IVYKCIDNNLNRIVALKLIKSESLDDESYSRIIREAETTARL 64 Query: 531 AHAHVVRYYCTERDKQFRYIALELCSAT-LQDYVEKKLNFECKIDSV-EILRQATMGLSH 588 +H ++V Y +++ ++ +E L DY++ K K+D + ++ T LS+ Sbjct: 65 SHPNIVSIYDMQKEDNRFFMVIEYIDGKDLLDYIDNK---PLKLDEILSLIIPITSALSY 121 Query: 589 LHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWI 648 H ++HRD+KP N+++S GE + M DFGL+K L+ R +R + GT ++ Sbjct: 122 AHKNGVLHRDIKPENIMVSK---NGEPKLM--DFGLAKALD--RPGITRAGTIVGTPAYL 174 Query: 649 APEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 +PE G+ + D++SLGCV YY +S G+ PF Sbjct: 175 SPESALGKESDNRSDLYSLGCVLYY-MSTGRPPF 207 >UniRef50_O75385 Cluster: Serine/threonine-protein kinase ULK1; n=32; Eumetazoa|Rep: Serine/threonine-protein kinase ULK1 - Homo sapiens (Human) Length = 1050 Score = 85.8 bits (203), Expect = 5e-15 Identities = 66/230 (28%), Positives = 113/230 (49%), Gaps = 23/230 (10%) Query: 467 MEIGEGEMK-IGKITFQTDQVLGKGCEGTFVYRGTF-DKRDVAV------KRLLPECFTF 518 ME G G + +GK F ++G G V++G +K D+ V K+ L + T Sbjct: 1 MEPGRGGTETVGKFEFSRKDLIGHGAFAV-VFKGRHREKHDLEVAVKCINKKNLAKSQTL 59 Query: 519 ADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVE 577 +E+ +L+E H ++V Y + Y+ +E C+ L DY+ D++ Sbjct: 60 LGKEIKILKELK-HENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLS--EDTIR 116 Query: 578 ILRQATMGLSHL-HSMDIVHRDVKPHNVLLSMPSG----TGEVRAMISDFGLSKKLNIGR 632 + Q G L HS I+HRD+KP N+LLS P+G +R I+DFG ++ L Sbjct: 117 LFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNM 176 Query: 633 VSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 ++ + + G+ ++APE+I + D++S+G + Y L+ G+ PF Sbjct: 177 MA----ATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLT-GKAPF 221 >UniRef50_UPI0000D556BE Cluster: PREDICTED: similar to CG7186-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG7186-PA - Tribolium castaneum Length = 720 Score = 85.4 bits (202), Expect = 7e-15 Identities = 64/224 (28%), Positives = 116/224 (51%), Gaps = 23/224 (10%) Query: 532 HAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLH 590 H ++ Y D + Y+ LELC + L+ Y++ K E ++ S I++Q G+ +LH Sbjct: 65 HPSILELYTFFEDANYVYLVLELCHNGELRQYIKTKALTESEVSS--IMKQVVEGMKYLH 122 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650 + +I+HRD+ N+LL T +++ I+DFGL+ +L+ R + + + GT +I+P Sbjct: 123 THNILHRDISLSNLLL-----TKDMQVKIADFGLATQLS--RPD-EKHTTMCGTPNFISP 174 Query: 651 EMINGERTTTSIDIFSLGCVFYYVLSKGQHPFG--DVLRRQANILTGDYNL-DHLDKILP 707 E+++ D++ LGC+ Y +L G PF V I++ +++L HL P Sbjct: 175 EVLSRTSHGLEADVWGLGCLLYNLL-VGSPPFDTHGVKNTLNRIVSANFHLPSHLS---P 230 Query: 708 EEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFL 751 E K LI +++ P R + IL++P Q +++ L Sbjct: 231 E-----AKDLINSLLQKNPKDRIKLDQILEHPFITRGQLLMSHL 269 >UniRef50_A6G2I7 Cluster: Serine/threonine protein kinase; n=1; Plesiocystis pacifica SIR-1|Rep: Serine/threonine protein kinase - Plesiocystis pacifica SIR-1 Length = 875 Score = 85.4 bits (202), Expect = 7e-15 Identities = 71/228 (31%), Positives = 117/228 (51%), Gaps = 24/228 (10%) Query: 472 GEMKIGKITFQTDQVLGKGCEGTF--VYRGTFDKRDVAVKRLLPECFTFAD------REV 523 GE+ G+ ++ + +LG+G G+ V+ D+R +A+K LL T REV Sbjct: 13 GELFAGR--YRVEALLGRGGMGSVYRVHDRELDER-IALK-LLDAASTSGSSVERFRREV 68 Query: 524 ALLRESDAHAHVVRYYCTERDKQFRYIALELCSAT-LQDYVEKKLNFECKIDSVEILRQA 582 L R H +V R Y ++ +EL + L+D++ K ++ VE+ Q Sbjct: 69 RLARRV-THHNVARTYDLGEHGGLHFLTMELVEGSNLRDWLRKFRPNPARV--VELAGQI 125 Query: 583 TMGLSHLHSMDIVHRDVKPHNVLLSMPS-----GTGEVRAMISDFGLSKKLNIGRVSFSR 637 GL H+ I+HRD+KP NVLL + G +R ++DFG+++ V Sbjct: 126 AAGLGSAHAAGIIHRDLKPSNVLLDLSGGPQTRGASAMRVALTDFGVARMSAEQTVGGGG 185 Query: 638 RSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GD 684 R G+ GT ++APE + GE TT + D+++LG + + +L+ G+ PF GD Sbjct: 186 R-GMLGTPAYMAPEQVAGEETTPATDLYALGLMIFEMLA-GRLPFSGD 231 >UniRef50_A6CD99 Cluster: Probable serine/threonine-protein kinase pknB; n=1; Planctomyces maris DSM 8797|Rep: Probable serine/threonine-protein kinase pknB - Planctomyces maris DSM 8797 Length = 1430 Score = 85.4 bits (202), Expect = 7e-15 Identities = 60/184 (32%), Positives = 97/184 (52%), Gaps = 14/184 (7%) Query: 504 RDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSAT-LQDY 562 RD A +L + F + A LR H ++V Y + + YIALE T L + Sbjct: 23 RDKAENPVLVKRFKAEGQAAAHLR----HENIVSVYDAGEEDGYLYIALEYVEGTDLHNL 78 Query: 563 VEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDF 622 + K+ + S+EI+ Q T LSH + IVHRD+KP N+L+ + G V+ ++D Sbjct: 79 INKRNRIPVR-RSLEIITQVTEALSHAYQQGIVHRDIKPANILIRL---DGVVK--LTDL 132 Query: 623 GLSKKLNIGRVSFSRRSGVT-GTDGWIAPEMINGERTT-TSIDIFSLGCVFYYVLSKGQH 680 GL++ ++ + R+G T GT ++APE + DI+SLGC +Y++L+ G+ Sbjct: 133 GLARSIDDNTETSITRAGTTVGTVDYMAPEQARDSKAADIRSDIYSLGCTWYHMLT-GRA 191 Query: 681 PFGD 684 PF + Sbjct: 192 PFSE 195 >UniRef50_A3ZWN5 Cluster: Probable serine/threonine-protein kinase pknA; n=1; Blastopirellula marina DSM 3645|Rep: Probable serine/threonine-protein kinase pknA - Blastopirellula marina DSM 3645 Length = 613 Score = 85.4 bits (202), Expect = 7e-15 Identities = 53/164 (32%), Positives = 88/164 (53%), Gaps = 11/164 (6%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578 +RE+ L+ H H+VR + + + A+EL +L + +++K ++ + ++ EI Sbjct: 54 EREIETLKTLK-HPHIVRLFGYGEEPAGMFYAMELVDGNSLSELIQRKRDYTWR-EAFEI 111 Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638 GL H H ++HRDVKP N+L+ G V+ ISDFG+++ G + Sbjct: 112 GLAIAQGLKHAHDFGVIHRDVKPANILIDKE---GNVK--ISDFGIARLF--GATGVTAD 164 Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 G+ GT ++APE GE + D++SLG V Y +L+K Q PF Sbjct: 165 GGIIGTADFMAPEQAFGEPVSPRSDLYSLGAVIYAMLAK-QPPF 207 >UniRef50_Q10NR1 Cluster: Mitogen-activated protein kinase 1, putative, expressed; n=3; Oryza sativa|Rep: Mitogen-activated protein kinase 1, putative, expressed - Oryza sativa subsp. japonica (Rice) Length = 597 Score = 85.4 bits (202), Expect = 7e-15 Identities = 66/228 (28%), Positives = 114/228 (50%), Gaps = 19/228 (8%) Query: 514 ECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECK 572 +C ++E+ALL + + H ++V+YY T+++ YI LEL + +L +K + Sbjct: 360 QCIFQLEQEIALLSQFE-HENIVQYYGTDKEDSKLYIFLELVTQGSLASLYQKYRLRDTH 418 Query: 573 IDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGR 632 + + RQ GL++LH +IVHRD+K N+L+ G V+ ++DFGL+K++ Sbjct: 419 VSAYT--RQILNGLTYLHERNIVHRDIKCANILV---HANGSVK--LADFGLAKEI---- 467 Query: 633 VSFSRRSGVTGTDGWIAPEMINGERT-TTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQAN 691 F+ GT W+APE++N + T DI+SLGC +L++ Q P+ + QA Sbjct: 468 TKFNVLKSCKGTVYWMAPEVVNPKTTYGPEADIWSLGCTVLEMLTR-QLPYPGLEWTQAL 526 Query: 692 ILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739 G + L + + I + P RP +L++P Sbjct: 527 YRIGKGEPPAIPNCLSRD----ARDFISQCVKPNPQDRPSAAKLLEHP 570 >UniRef50_Q23FR5 Cluster: Protein kinase domain containing protein; n=2; Oligohymenophorea|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 524 Score = 85.4 bits (202), Expect = 7e-15 Identities = 66/202 (32%), Positives = 103/202 (50%), Gaps = 17/202 (8%) Query: 487 LGKGCEGTF---VYRGTFDKRDV--AVKRLLPECFTFADREVALLRESDAHAHVVRYYCT 541 LG G G +R T D+R V K L + F D E+ +L+E D H ++++ Y Sbjct: 57 LGSGAFGVVFLATHRITGDERAVKAVAKDRLSDKQQFQD-EINILKELD-HPNIIKLYEV 114 Query: 542 ERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVK 600 + Y+ E C L YV + + K D+ I+RQ +S++H ++HRD+K Sbjct: 115 YESESTIYLVTEYCEGGELFQYVVQNKRLQEK-DAALIMRQLFSAVSYIHDNGVIHRDLK 173 Query: 601 PHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTT 660 P N LL S ++ + DFG+SKK G V + +GT +IAPE+I G+ + Sbjct: 174 PENFLLKKKSDPTTIKMI--DFGISKKFKKGEVLRQQ----SGTPYYIAPEVIEGQ-YSE 226 Query: 661 SIDIFSLGCVFYYVLSKGQHPF 682 +D ++LG + Y +LS G PF Sbjct: 227 QVDNWALGVILYILLS-GTPPF 247 >UniRef50_A7SP26 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 304 Score = 85.4 bits (202), Expect = 7e-15 Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 17/177 (9%) Query: 585 GLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGT 644 GL +LH I+HRD+KP+N+L T ++ I+DFGLSK S + G Sbjct: 31 GLHYLHGKSILHRDLKPNNLLYHFQDETPRLK--IADFGLSKDTTSASQSSTVIGTNVGC 88 Query: 645 DGWIAPEMING-ERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQAN-----ILTGDYN 698 W+APE+ + + D+FS G V +Y++SKG+HPF + Q N I T Sbjct: 89 KVWMAPEVSRAPSKHSQKSDVFSCGLVLHYIMSKGKHPFAKESQTQENARIWEISTASSI 148 Query: 699 LDHL----DKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFL 751 ++ + + PE + +VI+ L R P RP ++ +P+FW + L ++ Sbjct: 149 VNDIKSLHSSLGPEAKDIVIQALAR-----DPEDRPSASNMIGHPVFWSEDKKLRYI 200 >UniRef50_A2F620 Cluster: STE family protein kinase; n=1; Trichomonas vaginalis G3|Rep: STE family protein kinase - Trichomonas vaginalis G3 Length = 1308 Score = 85.4 bits (202), Expect = 7e-15 Identities = 80/268 (29%), Positives = 129/268 (48%), Gaps = 28/268 (10%) Query: 481 FQTDQVLGKGCEGTFVYRG-TFDKRD-VAVKRL----LPECFTFADREVALLRESDAHAH 534 FQ LG+G G VY+G D D VA+K + P+ +E+ L+ + H + Sbjct: 40 FQLGPKLGRGAFGC-VYQGLNKDTGDYVAIKTISLTRFPDALDSVQQEIDLMAPLE-HPN 97 Query: 535 VVRYYCTERDKQFRYIALELCSATLQDYVEKKL-NFECKIDSVEILRQATMGLSHLHSMD 593 VV+Y + + K F YI +E V+KK NF + S + L + +GL +LH Sbjct: 98 VVKYITSHQTKDFLYIVMEFAEGGSLQNVQKKFENFNEHLAS-KYLYEVLLGLKYLHEQS 156 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKL--NIGRVSFSRRSGVTGTDGWIAPE 651 I+HRD+K N+LL+ + +SDFG+S KL N + S+ S W APE Sbjct: 157 IIHRDIKAANILLT------KGHCKLSDFGISVKLTDNKNPDALSQCSPF-----WAAPE 205 Query: 652 MINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEEL 711 +I+ E T DI+SLG + L GQ P+ ++ +A + + + LP++ Sbjct: 206 VISMEPITEKCDIWSLG-ITAIELFAGQPPYFELNAVRAMFQI----VQNPEPPLPKDIS 260 Query: 712 VVIKILIRAMISAKPSARPPCETILKYP 739 K + + ++ + R E +LK+P Sbjct: 261 ANFKDFLTSCLTKNVTFRKNTEQLLKHP 288 >UniRef50_A0E1K1 Cluster: Chromosome undetermined scaffold_73, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_73, whole genome shotgun sequence - Paramecium tetraurelia Length = 715 Score = 85.4 bits (202), Expect = 7e-15 Identities = 77/273 (28%), Positives = 134/273 (49%), Gaps = 29/273 (10%) Query: 481 FQTDQVLGKGCEGTFVYRGTFD-KRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYY 539 FQ +G G +G V + + VA+K + D+E +LL + + H ++V ++ Sbjct: 293 FQYIDSIGGGSQGKVVKAQSKGLNQSVAIKIIERHKNKAQDQEASLLEKCN-HYNIVHFH 351 Query: 540 CTERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRD 598 YI +E L TLQ+ ++K+L E K+ + +++Q GLS+LH+ I+HRD Sbjct: 352 KLLYTHNHLYIIMEYLQGITLQEVMQKQLR-ENKMRN--LIKQILEGLSYLHNQGIIHRD 408 Query: 599 VKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERT 658 +KP N+ L + V+ + D GLS ++ +++ + GT ++APE+ Sbjct: 409 LKPSNIYLVRENNKSIVKLI--DLGLSYQICSHKIANKQ----CGTLLYMAPELAQDVPY 462 Query: 659 TTSIDIFSLGCVFYYVLSKGQHPF-------GDVLRRQANILTGDYNLDHLDKILPEEEL 711 ++DIF+LG +FY + G+HPF D +R A + ++NLD + I P Sbjct: 463 NQTVDIFALGIIFYQLFHDGKHPFYVPGMRSSDYFKRLAKL---EFNLDFKENI-PS--- 515 Query: 712 VVIKILIRAMISAKPSARPPCETILKYPMFWCK 744 + K I+ ++ P R L +P W K Sbjct: 516 -MAKDFIQKTMALSPDDRMSAYQCLDHP--WIK 545 >UniRef50_Q0USU3 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 1499 Score = 85.4 bits (202), Expect = 7e-15 Identities = 80/267 (29%), Positives = 127/267 (47%), Gaps = 26/267 (9%) Query: 481 FQTDQVLGKGCEGTFVYRGTF--DKRDVAVKRLLPECFTFAD-----REVALLRESDAHA 533 FQ LGKG G+ VYR VA+K++ E AD E+ LL+ + H Sbjct: 71 FQLGDCLGKGAFGS-VYRALNWGTGETVAIKQVRLENLGAADLKNMEMEIDLLKNLN-HP 128 Query: 534 HVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592 ++V+Y R + YI LE C + +L + F + ++ + QA GL +LH Sbjct: 129 NIVKYNGFVRSSESLYIILEYCENGSLHSICKNFGKFPENLVAL-YMSQALHGLLYLHEQ 187 Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652 ++HRD+K N+L T E ++DFG++ K S +S V GT W+APE+ Sbjct: 188 GVIHRDIKGANILT-----TKEGLVKLADFGVATKQ-----SGLDQSSVVGTPYWMAPEV 237 Query: 653 INGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712 I TTS DI+SLGC ++ +G+ P+ + QA L N +H +P Sbjct: 238 IELSGATTSSDIWSLGCTVIELI-EGKPPYHKLQPMQA--LFRIVNDEH--PPIPGSASP 292 Query: 713 VIKILIRAMISAKPSARPPCETILKYP 739 +++ + P+ R + +LK+P Sbjct: 293 LLREFLMECFQKNPTLRISAKRLLKHP 319 >UniRef50_A7TJU8 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 977 Score = 85.4 bits (202), Expect = 7e-15 Identities = 79/276 (28%), Positives = 134/276 (48%), Gaps = 29/276 (10%) Query: 478 KITFQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLL---PECFTFADREVALLRESDAH 532 +I +Q V+GKG G VY+ K + VA+K + E E+ LL+ + H Sbjct: 60 RIQYQLKAVIGKGSFGV-VYKAVNRKTNQVVAIKEVNYDNDEELNDIMSEIHLLKNLN-H 117 Query: 533 AHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHS 591 ++V+Y+ + YI LE CS +L+ + +I++ +RQ GLS+LH Sbjct: 118 VNIVKYHGFIQKMDTLYIILEYCSRGSLKKLISPNRGIP-EIEAQSYIRQTLQGLSYLHE 176 Query: 592 MDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPE 651 ++HRD+K N+LL + V+ ++DFG+S K+N ++ + + G+ W+APE Sbjct: 177 QGVIHRDIKSANLLL---DSSNVVK--LADFGVSTKVNNASMAMT----LAGSLNWMAPE 227 Query: 652 MINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEEL 711 +I +T DI+SLG +L+ G PF +++ NI Y +++ D LP E Sbjct: 228 IIGNRGASTLSDIWSLGATVVELLT-GNPPFHNLV--DVNIY---YAIEN-DTYLPPENK 280 Query: 712 V--VIKILIRAMISAKPSARPPCETILKYPMFWCKQ 745 V V + RP + +L++ W Q Sbjct: 281 VSHVAANFLSCCFQKNMYLRPTAKQLLQHE--WLSQ 314 >UniRef50_UPI0000498BDB Cluster: cell division control protein 7; n=1; Entamoeba histolytica HM-1:IMSS|Rep: cell division control protein 7 - Entamoeba histolytica HM-1:IMSS Length = 1071 Score = 85.0 bits (201), Expect = 9e-15 Identities = 57/179 (31%), Positives = 91/179 (50%), Gaps = 10/179 (5%) Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQ 581 E+ LL++ H H+VRY + F YI +E + + KK N + S + + Q Sbjct: 47 EIRLLKKLK-HKHIVRYIASTESHGFLYIIMEYMESGSLLNIVKKFNHLNESLSAKYIHQ 105 Query: 582 ATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIG-RVSFSRRSG 640 GL+ +H IVHRD+K N+L++ G V+ I+DFG+S ++N + Sbjct: 106 VLDGLAFIHDQGIVHRDIKAANILVAK---DGSVK--IADFGVSVQMNGNEKQETGSDED 160 Query: 641 VTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQA--NILTGDY 697 GT W+APE+I + TT DI++LGC +++ G P+ D+ A I+ DY Sbjct: 161 PIGTPNWMAPEVIQMQGTTVKADIWALGCTVIELIT-GNPPYYDLNPTAALYKIVNDDY 218 >UniRef50_UPI000023D1D8 Cluster: hypothetical protein FG05484.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG05484.1 - Gibberella zeae PH-1 Length = 849 Score = 85.0 bits (201), Expect = 9e-15 Identities = 69/227 (30%), Positives = 107/227 (47%), Gaps = 21/227 (9%) Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEI-- 578 RE++LLR+ H ++V+Y + I LE V+ LN + + Sbjct: 630 REISLLRDL-RHPNIVQYLGCSSTADYLNIFLEYVPG---GSVQTMLNSYGALPEPLVRS 685 Query: 579 -LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKL---NI--GR 632 +RQ GLS+LH+ DI+HRD+K N+L+ G ++ ISDFG+SKKL NI G Sbjct: 686 FVRQILTGLSYLHNQDIIHRDIKGANILV---DNKGTIK--ISDFGISKKLEATNILNGA 740 Query: 633 VSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANI 692 + R + G+ W+APE++ T DI+SLGC+ +++ G HPF D + QA Sbjct: 741 NNSKHRPSLQGSVFWMAPEVVKQTSYTRKADIWSLGCLVVEMMT-GSHPFPDCSQLQAIF 799 Query: 693 LTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739 G +PE K + + RP + ++ P Sbjct: 800 KIGG---GKAAPTIPEHASEAAKEFLAQTFEIDHNLRPSADQLILSP 843 >UniRef50_Q6PHV6 Cluster: Serine/threonine kinase 17b; n=1; Danio rerio|Rep: Serine/threonine kinase 17b - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 354 Score = 85.0 bits (201), Expect = 9e-15 Identities = 47/165 (28%), Positives = 87/165 (52%), Gaps = 8/165 (4%) Query: 578 ILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSR 637 ++RQ G+ LH +VH D+KP N+LL+ S G+++ I DFGL+++L S Sbjct: 135 LIRQMLEGIHLLHQSSVVHLDLKPQNILLTSLSPLGDIK--IVDFGLARRLG----SAGE 188 Query: 638 RSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY 697 + GT ++APE++N E TT+ D++S+G V Y+L G+ PF +++ + Sbjct: 189 LREILGTPEYVAPEILNYEPITTATDLWSVG-VITYMLVTGESPFAGDDKQETFLNVSQV 247 Query: 698 NLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFW 742 N+++ + + + + + ++ A P RP + +P W Sbjct: 248 NVEYSRETFSRVSELAVDFIRKLLVKA-PEDRPSAADCMTHPWLW 291 >UniRef50_Q47SX3 Cluster: Tyrosine protein kinase:Serine/threonine protein kinase; n=1; Thermobifida fusca YX|Rep: Tyrosine protein kinase:Serine/threonine protein kinase - Thermobifida fusca (strain YX) Length = 624 Score = 85.0 bits (201), Expect = 9e-15 Identities = 82/261 (31%), Positives = 128/261 (49%), Gaps = 30/261 (11%) Query: 487 LGKGCEGTFVYRGTFDKRD--VAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTER- 543 LG G GT VY G ++ VA+K + PE F + A R+ +A V +CT + Sbjct: 30 LGSGGMGT-VYLGRAPEKGTHVAIKVIRPE-LAFDEATRARFRDEMENARKVASFCTAKV 87 Query: 544 ----DKQFR-YIALELCSAT-LQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHR 597 Q R Y+ E + T L +++ + + L A L+ +H +VHR Sbjct: 88 LDHGTFQNRPYMVTEYIAGTALAEHIAEHGPLDSGTLHGFALGVAA-ALAAIHKAGLVHR 146 Query: 598 DVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGER 657 D+KP NVLLS+ SG + DFG+++ LN S ++ V G+ GW+APE + E+ Sbjct: 147 DLKPANVLLSL-SGP-----RVIDFGIARALNTS-TSHTQTGIVMGSPGWMAPEQLLEEK 199 Query: 658 TTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEELVVIK 715 TT DIF+ GC+ + G+HPF GD + +L + ++ +LD P + LV Sbjct: 200 VTTKADIFAWGCLVAFA-GNGRHPFGNGDAMTLGKRMLFAEPDIGNLDP--PLDRLVA-- 254 Query: 716 ILIRAMISAKPSARPPCETIL 736 RA ++ P RP + +L Sbjct: 255 ---RA-LAKDPDQRPTAQELL 271 >UniRef50_A6G500 Cluster: Serine/threonine protein kinase; n=1; Plesiocystis pacifica SIR-1|Rep: Serine/threonine protein kinase - Plesiocystis pacifica SIR-1 Length = 626 Score = 85.0 bits (201), Expect = 9e-15 Identities = 70/219 (31%), Positives = 109/219 (49%), Gaps = 24/219 (10%) Query: 481 FQTDQVLGKGCEGTFVYRGTFD--KRDVAVKRLLPECFTFADREVALLRESDAHA----- 533 ++ D VLG G G V+RG KRDVA+K L PE D + E +AH+ Sbjct: 9 YRVDAVLGAGGMGA-VFRGHHSGLKRDVAIKVLHPEISQGRDASMTKRFEREAHSASRLD 67 Query: 534 --HVVRY--YCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSH 588 + VR + T D +Y+ +EL + L D ++ + ++ ++RQ GL H Sbjct: 68 HPNCVRVTDFGTTGDGT-KYLVMELLTGGELADRLDAAWD---PSEATAVMRQIFAGLEH 123 Query: 589 LHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNI-----GRVSFSRRSGVTG 643 H +VHRD+KP NV ++ EV I DFG++K L+ G +R+ V G Sbjct: 124 AHHFGVVHRDLKPENVFMTQDYRGREV-VKIVDFGIAKLLDAGEGEGGHEKLTRQGVVFG 182 Query: 644 TDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 T ++APE G + D+++ G +FY +L+ G+ PF Sbjct: 183 TPRFMAPEQAAGGKIDERTDLYAAGLIFYELLA-GRPPF 220 >UniRef50_A0E202 Cluster: Chromosome undetermined scaffold_74, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_74, whole genome shotgun sequence - Paramecium tetraurelia Length = 587 Score = 85.0 bits (201), Expect = 9e-15 Identities = 75/251 (29%), Positives = 123/251 (49%), Gaps = 25/251 (9%) Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILR 580 E+ L+R+ D H ++++ + Y+ LEL L + ++KK+ F K + + I++ Sbjct: 211 EIKLMRQLD-HPNIIKLHEVHETSNSLYVCLELLEGGQLYEQLKKKVIFSNK-EILTIIK 268 Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640 GL H+HS DI+HRD+K N+L P+ V ++DFGL+ +N + R Sbjct: 269 GLLEGLKHVHSKDIMHRDIKLENILFKKPNQIESV--CLADFGLATYVNEEVYLYCR--- 323 Query: 641 VTGTDGWIAPEMINGERTTTS----IDIFSLGCVFYYVLSKGQHPFG----DVLRRQANI 692 GT G++APE+IN + TT DI+SLG VF+ +L+ G+ F + Q Sbjct: 324 -CGTPGFVAPEVINIKDLTTKYDKVCDIYSLGLVFHLLLT-GKPAFTGRSYTTIVNQNKE 381 Query: 693 LTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF--WCKQSILNF 750 + D I+P+ L L++ M+ A P R E L++ F + +I F Sbjct: 382 AKIQWKSSAFD-IIPKAAL----NLLKRMLEADPKLRITAEEALQHNYFNPYHIPNIAQF 436 Query: 751 LQDVSDQVESC 761 D D +SC Sbjct: 437 EDDNIDIDDSC 447 >UniRef50_A0DM08 Cluster: Chromosome undetermined scaffold_56, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_56, whole genome shotgun sequence - Paramecium tetraurelia Length = 521 Score = 85.0 bits (201), Expect = 9e-15 Identities = 79/288 (27%), Positives = 137/288 (47%), Gaps = 32/288 (11%) Query: 469 IGEGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFT--FADREVALL 526 + E +IG T ++GKG G VY T D + K++L F DRE+ +L Sbjct: 1 MSRSEAQIGIYTLNKKNMIGKGSFG-LVYTATCDGEEFCAKQILSNGAQKKFTDREIQIL 59 Query: 527 R-------ESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDYVE--KKLN-FECKIDS 575 R ++ H++ ERD + Y+ +E C L+ +E KK N + +S Sbjct: 60 RMLRSSPIQNPNIVHIIDVIQNERDSEV-YVIMEYCRGGDLKKEMEQKKKRNEWYTHQES 118 Query: 576 VEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSF 635 + I+ Q G L+ +D +HRD+KP N+L+S SG + ++DFG+ +S Sbjct: 119 LNIVAQIIKGYKSLYDVDFIHRDIKPANILIS--SGFYK----LADFGMGI-----FISP 167 Query: 636 SRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTG 695 S+ + + GT + AP++ + T D++SLG +FY ++ K + P ++ QA +T Sbjct: 168 SQSTNI-GTPAYSAPQIFFDSKYTNKCDVYSLGVIFYELIFK-EKPIN--VKTQAEQITL 223 Query: 696 DYNLDHLDKILPEEELVVIK--ILIRAMISAKPSARPPCETILKYPMF 741 P +E + I+ +LI M+S + R + +P+F Sbjct: 224 LRKTQENKITCPRDENLDIRVCVLIEQMLSYEEKQRIGWNDLFIHPLF 271 >UniRef50_A0D824 Cluster: Chromosome undetermined scaffold_40, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_40, whole genome shotgun sequence - Paramecium tetraurelia Length = 414 Score = 85.0 bits (201), Expect = 9e-15 Identities = 64/201 (31%), Positives = 107/201 (53%), Gaps = 16/201 (7%) Query: 485 QVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERD 544 Q +G G V+ G +D + VA+K + P +EV +L ES H +Y+ ++ Sbjct: 13 QQIGHGAFSQ-VFLGEYDSKKVAIKVMDPIYLDQFKKEVEIL-ESIHHQSFAQYFYSKET 70 Query: 545 KQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHN 603 + YI E L TL +++ E I +I+ + +S+LHS DI+HRD+KP N Sbjct: 71 ENSLYIVQEYLEGKTLTQFIKTVQMEETHIK--QIIIELLDSVSYLHSQDIIHRDIKPDN 128 Query: 604 VLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSID 663 +++ T E + + DFGLS + ++S+ + GT ++APEMI + S+D Sbjct: 129 III-----TTEGQLKLIDFGLSSH-SESKLSYDK----CGTLLFMAPEMIFKQPYLKSVD 178 Query: 664 IFSLGCVFYYVLSKGQHPFGD 684 I+S G + Y +++K +HPF D Sbjct: 179 IWSCGIIAYQLINK-KHPFWD 198 >UniRef50_O42625 Cluster: MAPKK kinase; n=6; Pezizomycotina|Rep: MAPKK kinase - Neurospora crassa Length = 666 Score = 85.0 bits (201), Expect = 9e-15 Identities = 61/177 (34%), Positives = 97/177 (54%), Gaps = 16/177 (9%) Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNF-ECKIDSVEI 578 RE+ LLR+ H ++V+Y ++ I LE ++Q +++ E + S Sbjct: 445 REITLLRDLQ-HPNIVQYLGCSSSAEYLNIFLEYVPGGSVQTMLDQYGALPESLVRS--F 501 Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKL---NI--GRV 633 +RQ GLS++H+ DI+HRD+K N+L+ G ++ ISDFG+SKKL NI G Sbjct: 502 VRQILQGLSYVHNRDIIHRDIKGANILV---DNKGTIK--ISDFGISKKLEATNILNGAN 556 Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQA 690 + R + G+ W+APE++ T DI+SLGC+ +++ G HPF D + QA Sbjct: 557 NNKHRPSLQGSVFWMAPEVVKQTSYTRKADIWSLGCLVVEMMT-GTHPFPDCTQLQA 612 >UniRef50_Q9H4B4 Cluster: Serine/threonine-protein kinase PLK3; n=21; Eutheria|Rep: Serine/threonine-protein kinase PLK3 - Homo sapiens (Human) Length = 646 Score = 85.0 bits (201), Expect = 9e-15 Identities = 64/220 (29%), Positives = 103/220 (46%), Gaps = 15/220 (6%) Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQ 581 E+ L R+ H H+VR+ D YI LELCS ++ K + + + LRQ Sbjct: 110 EIELHRDLQ-HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQ 168 Query: 582 ATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGV 641 GL +LH I+HRD+K N + T + + DFGL+ +L R+ + Sbjct: 169 ILSGLKYLHQRGILHRDLKLGNFFI-----TENMELKVGDFGLAARLEPPE---QRKKTI 220 Query: 642 TGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDH 701 GT ++APE++ + D++SLGCV Y +L G PF A++ + Sbjct: 221 CGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLC-GSPPF-----ETADLKETYRCIKQ 274 Query: 702 LDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741 + LP + + L+ A++ A P RP + IL++ F Sbjct: 275 VHYTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFF 314 >UniRef50_P54740 Cluster: Serine/threonine-protein kinase pkaB; n=3; Streptomyces|Rep: Serine/threonine-protein kinase pkaB - Streptomyces coelicolor Length = 417 Score = 85.0 bits (201), Expect = 9e-15 Identities = 67/218 (30%), Positives = 112/218 (51%), Gaps = 15/218 (6%) Query: 475 KIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDA--- 531 KIG + Q+LG+G GT V+ G VA+K L + + + ++E A Sbjct: 4 KIGS-RYTAHQILGRGSAGT-VWLGEGPDGPVAIKLLREDLASDQELVSRFVQERTALLG 61 Query: 532 --HAHVVRYYCTERDKQFRYIALELCSAT-LQDYVEKKLNFECKIDSVEILRQATMGLSH 588 H HVV D + ++L T L+ ++++ + +V ++ GL+ Sbjct: 62 LDHPHVVSVRDLVVDGNDLALVMDLVRGTDLRTRLDRERRLAPEA-AVAVVADVADGLAA 120 Query: 589 LHSMDIVHRDVKPHNVLLSM--PSGTGEVR-AMISDFGLSKKLNIGRVSFSRRSGVTGTD 645 H+ +VHRDVKP NVLL M P G G A+++DFG++K ++ R +R + + GT Sbjct: 121 AHAAGVVHRDVKPENVLLDMQGPLGPGGSHPALLTDFGVAKLIDTPR--RTRATKIIGTP 178 Query: 646 GWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFG 683 ++APE++ G ++DI++L V Y +L+ G PFG Sbjct: 179 DYLAPEIVEGLPPRAAVDIYALATVLYELLA-GFTPFG 215 >UniRef50_UPI0000DB7B8A Cluster: PREDICTED: similar to CG8789-PA, isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar to CG8789-PA, isoform A - Apis mellifera Length = 895 Score = 84.6 bits (200), Expect = 1e-14 Identities = 77/247 (31%), Positives = 121/247 (48%), Gaps = 21/247 (8%) Query: 485 QVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERD 544 Q LG G +G V+ G +K VAVK++ + ++ LR+ + H ++V++ Sbjct: 153 QWLGSGAQGA-VFSGKLNKEVVAVKKVREP----RETDIRHLRKLN-HPNIVQFKGVCTQ 206 Query: 545 KQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHN 603 I +E C L D + V +Q G+++LH+ I+HRD+K N Sbjct: 207 APCYCIIMEFCPYGPLYDLLRAGEPVPPP-RLVSWSKQIAAGMAYLHAHKIIHRDLKSPN 265 Query: 604 VLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSID 663 VL+ G GEV ISDFG S++ N S R GT W+APE+I E + +D Sbjct: 266 VLI----GQGEV-VKISDFGTSREWN----EISTRMSFAGTVAWMAPEIIRNEPCSEKVD 316 Query: 664 IFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMIS 723 I+S G V + +LS G+ P+ DV + I+ G N + L +P ++L++ + Sbjct: 317 IWSYGVVLWELLS-GEIPYKDV--DSSAIIWGVGN-NSLHLPIPASCPEGYRLLVKQCWA 372 Query: 724 AKPSARP 730 AKP RP Sbjct: 373 AKPRNRP 379 >UniRef50_Q7UVF2 Cluster: Serine/threonine protein kinase; n=1; Pirellula sp.|Rep: Serine/threonine protein kinase - Rhodopirellula baltica Length = 504 Score = 84.6 bits (200), Expect = 1e-14 Identities = 81/258 (31%), Positives = 125/258 (48%), Gaps = 26/258 (10%) Query: 487 LGKGCEGTFVYRGTFD--KRDVAVKRLLPECFTFADREVALLRESDA-----HAHVVRYY 539 LGKG G VY G KR +A+K L + R E+ A H ++VR Y Sbjct: 91 LGKGGMG-MVYLGEHSVMKRQMALKILNSDSSRDERRIQRFQEEARASAQLDHPNIVRAY 149 Query: 540 CTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599 + YI +E V + +++ + QAT GL+H H I+HRD+ Sbjct: 150 DFNQSNGKLYIVMEYIDGIDLHQVVARDGVMSIAAAIDAMYQATGGLAHAHERGIIHRDI 209 Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG---VTGTDGWIAPEM-ING 655 KP N++L G V+ +SD GL++ IG S +G +TGT ++APE +N Sbjct: 210 KPSNLML---RSDGVVK--VSDMGLAR---IGWSEGSGDTGKRRLTGTADFVAPEQALNS 261 Query: 656 ERTTTSIDIFSLGCVFYYVLSKGQHPF-GD-VLRRQANILTGDYNLDHLDKILPEEELVV 713 DI+SLGC +++L+ G+ P+ GD V +R A T + + K+ P+ + Sbjct: 262 HSVDARADIYSLGCTLFFLLT-GRPPYKGDTVAQRLAKHQTAP--VPDVRKLRPDCPAPL 318 Query: 714 IKILIRAMISAKPSARPP 731 +L R M++ KP+ RPP Sbjct: 319 ASLLTR-MMAKKPADRPP 335 >UniRef50_Q3ACF7 Cluster: Putative serine/threonine protein kinase; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: Putative serine/threonine protein kinase - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 764 Score = 84.6 bits (200), Expect = 1e-14 Identities = 71/230 (30%), Positives = 112/230 (48%), Gaps = 23/230 (10%) Query: 481 FQTDQVLGKG--CEGTFVYRGTFDKRDVAVKRL----LPECFTFADREVALLRESDAHAH 534 ++ + ++G+G + + Y D R+VAVK + LP A L H + Sbjct: 216 YRLEDLIGEGNFSKVYWAYDNKLD-REVAVKEINLTDLPGDIKDKIYNEAQLMAKINHEN 274 Query: 535 VVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 +V+ Y T Y+ +EL TL +Y+E+K +V I+ Q LS++H + Sbjct: 275 IVKLYDTFYFDDKIYLIIELVQGKTLVEYLEEKGGMLSVKKAVNIMIQIAKALSYIHQHN 334 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 I+HRD+KP N+L+S T ++ I+DFG++ +LN + GT +APE I Sbjct: 335 IIHRDLKPENILIS----TDDI-VKITDFGIA-QLN---EEEKEEGFILGTPVVMAPEQI 385 Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLD 703 DIF+LGC+FYY+L+ G +PF N YN+ H D Sbjct: 386 LKTGIDQRTDIFALGCIFYYLLT-GHYPFSG-----TNFSELSYNILHFD 429 >UniRef50_Q3DW89 Cluster: Protein kinase:PASTA:Serine/threonine protein kinase, active site; n=1; Chloroflexus aurantiacus J-10-fl|Rep: Protein kinase:PASTA:Serine/threonine protein kinase, active site - Chloroflexus aurantiacus J-10-fl Length = 600 Score = 84.6 bits (200), Expect = 1e-14 Identities = 70/214 (32%), Positives = 108/214 (50%), Gaps = 21/214 (9%) Query: 481 FQTDQVLGKG-CEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----HAH 534 +Q +Q+LG+G ++ R R VA+K P T D E+ A H + Sbjct: 10 YQIEQLLGEGGMARVYLGRDLRLNRPVAIKIPHPHLMTDPDFMARFRHEAHAAAMVSHPN 69 Query: 535 VVRYYCTERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 +V Y +D YI +E + TL+ + ++ F +V I Q GL H Sbjct: 70 LVDVYDVGQDGDRHYIVMEYVAGTTLKQLINREAPFAIP-RAVRIAEQIARGLHAAHRAG 128 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS-RRSGVT-GTDGWIAPE 651 ++HRD+KP N+++ + G+VR I+DFG++K R+S + +GVT GT +IAPE Sbjct: 129 LIHRDIKPQNIIV---TDDGQVR--ITDFGVAK----SRLSTAMTETGVTLGTVDYIAPE 179 Query: 652 MINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GD 684 G T DI++LG V Y +L+ G+ PF GD Sbjct: 180 QAQGRAATPQSDIYALGVVLYEMLT-GRLPFTGD 212 >UniRef50_A4SBG1 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 272 Score = 84.6 bits (200), Expect = 1e-14 Identities = 73/255 (28%), Positives = 124/255 (48%), Gaps = 22/255 (8%) Query: 487 LGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDA------HAHVVRYYC 540 +G+G G V+RG + DVA+KRL +R +A + + H H+V++ Sbjct: 15 IGRGAFGE-VFRGKYRGTDVAIKRLCVLSDVSDERGLAEFKRELSFLTRLRHRHIVQFIG 73 Query: 541 TERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDV 599 I ++ C +L Y+ ++ + +A GL +LH+ DI+HRDV Sbjct: 74 ASTAPPNLCIIMDYCDKGSLYAYLHNPNKTLSAFKVLKWMSEAAKGLVYLHASDIIHRDV 133 Query: 600 KPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE-RT 658 K N+ + G ++ + DFGLS K + G + + GT ++APE++ G+ R Sbjct: 134 KSGNLFI---DDGGSIK--LGDFGLS-KFHTGASTSGGMMSLVGTYQFMAPELLEGQPRY 187 Query: 659 TTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDY-NLDHLDKI---LPEEELV 712 TT++D++S V + L++ + PF + Q A +L G+ +LD K LPEE + Sbjct: 188 TTAVDVYSFAVVMWECLTR-EDPFSGLSPMQIVAALLRGERPSLDDASKFAVRLPEEYIA 246 Query: 713 VIKILIRAMISAKPS 727 VI RA +P+ Sbjct: 247 VIARCWRADALERPT 261 >UniRef50_Q22AD4 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 1193 Score = 84.6 bits (200), Expect = 1e-14 Identities = 70/264 (26%), Positives = 132/264 (50%), Gaps = 20/264 (7%) Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPECFTFADREVALLRESDAHAHVVRY 538 F+ +LG+G G VY+ + VAVK + E + ++E+ +L+E + +VV+Y Sbjct: 21 FEILDLLGEGSYGQ-VYKALHKQTGELVAVKMVPNEGDSALEKEIRMLKECQSE-YVVKY 78 Query: 539 YCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATM-GLSHLHSMDIVH 596 Y + Q ++ +E C+A ++ D V K + + + Q+T+ GL +LHS I+H Sbjct: 79 YASYYKDQHLWLIMEYCAAGSIIDLV-KITRIQLNEQQIASILQSTLKGLQYLHSNKIIH 137 Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLS-KKLNIGRVSFSRRSGVTGTDGWIAPEMING 655 RD+K N+LL A ++DFG+S ++++ + ++ GT W+APE+I Sbjct: 138 RDIKAGNILLDQRG-----NAKLADFGVSFQQIH----TQAKAESKIGTPCWMAPEVIMH 188 Query: 656 ERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIK 715 + + DI+SLG + L++G+ P+ DV + + ++ P + Sbjct: 189 LKYDSKADIWSLG-ITAIELAEGEPPYSDV--KPSMVMAKIQQKPPQGLKNPSQWSQQFN 245 Query: 716 ILIRAMISAKPSARPPCETILKYP 739 ++ + P RP E +L++P Sbjct: 246 DFVKQCLQQDPQKRPTAEQLLQHP 269 >UniRef50_A2FTS4 Cluster: CAMK family protein kinase; n=2; Trichomonas vaginalis G3|Rep: CAMK family protein kinase - Trichomonas vaginalis G3 Length = 299 Score = 84.6 bits (200), Expect = 1e-14 Identities = 79/270 (29%), Positives = 133/270 (49%), Gaps = 28/270 (10%) Query: 487 LGKGCEGT-FVYRGTFDKRDVAVKRLLPECFT---FADREVALLRESDAHAHVVRYYCTE 542 +G+G T +V R T D +V +++P+ F D E+ +L + H ++V++ Sbjct: 13 IGRGVSSTVYVARNT-DTDEVVCIKVIPKAEKEKCFLDTEIKVLPTLN-HPNIVKFIDFL 70 Query: 543 RDKQFRYIALELCSA-TLQDYVEK-KLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVK 600 D + Y+ E C+ TL +VE KL E I + I++Q L ++H+ + HRD+K Sbjct: 71 EDLENYYLIEEYCNGETLTQFVESGKLLTERSI--LSIMQQLFSALMYIHAKGVSHRDLK 128 Query: 601 PHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGER-TT 659 P N+++ S + DFGLS N S RS G+ + +PE IN ++ Sbjct: 129 PDNIIIIDSS-----NIKVIDFGLSTDDN-----SSLRSTFCGSVAFASPECINHQKYDA 178 Query: 660 TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIR 719 + DI+S G + +Y LS GQ P+ + NI+ ++ ++ +P L+ IK +I Sbjct: 179 KAADIWSCGVICFY-LSTGQIPW-----KGNNIVQLMRSISAVNYYIPNSILIPIKSIIT 232 Query: 720 AMISAKPSARPPCETILKYPMFWCKQSILN 749 + PS RP E +L+ P F C + N Sbjct: 233 QCLCLDPSKRPTAEKLLESP-FLCTKGRRN 261 >UniRef50_A2EJ98 Cluster: AGC family protein kinase; n=2; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 430 Score = 84.6 bits (200), Expect = 1e-14 Identities = 65/261 (24%), Positives = 124/261 (47%), Gaps = 23/261 (8%) Query: 478 KITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVA-LLRESDA----- 531 K F +VLG+G G + + ++L + +++++ +L E DA Sbjct: 32 KNDFNIGRVLGRGAFGEVLKVQDIETGKYYAMKVLSKSRIAREKKLSYVLLERDAMTTLK 91 Query: 532 HAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLH 590 H +++R Y T +D Y +EL + LQ + + + + I + ++L Q + L+H+H Sbjct: 92 HPNIIRLYLTFQDPSNLYYVVELAENGDLQHVLNQYKSIDLPI-AKQLLGQTLLALAHMH 150 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650 I+HRD+KP N+LL + R I+DFG K +S+R G+ +++P Sbjct: 151 QHRIIHRDIKPENILLDHYN-----RVKITDFGTVKIYKENEPFYSQRGSFVGSPEYVSP 205 Query: 651 EMINGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPE 708 E +N + + D+++ GC+ + ++ G PF G I +G+Y ++P+ Sbjct: 206 ETLNETTISAATDLWAFGCLIFQFIT-GYSPFHTGSNYDTFQKIESGNY-------VIPD 257 Query: 709 EELVVIKILIRAMISAKPSAR 729 K +I+ ++ KP R Sbjct: 258 YVPEDAKDIIQKLLKVKPEER 278 >UniRef50_A0EHY9 Cluster: Chromosome undetermined scaffold_98, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_98, whole genome shotgun sequence - Paramecium tetraurelia Length = 517 Score = 84.6 bits (200), Expect = 1e-14 Identities = 78/285 (27%), Positives = 137/285 (48%), Gaps = 41/285 (14%) Query: 478 KITFQTDQVLGKGC-EGTFVYRGTFDKRDVAVKRLL-------PECFTFADREVALLRES 529 ++ + +++GKG + + FD + A K P+ + E+ ++R+ Sbjct: 135 QVNYDISKLIGKGTFASVYEAKSKFDSQMYAAKAFYKKTLFQDPKGKEQVENEIRIMRQL 194 Query: 530 DAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEIL-RQATMGLSH 588 + H +++ + +K Y+ ++L +Y K LN S +++ RQ GL Sbjct: 195 N-HPNLINLHEVYENKAQIYLIIDLARGGSLEYALKVLNGPVPFLSAKVIFRQIVEGLIG 253 Query: 589 LHSMDIVHRDVKPHNVLLS--MP-SGTGEV----RAMISDFGLS----KKLNIGRVSFSR 637 LH +I+HRD+KP N+L +P G + M+SDFG+S +KLN+ + Sbjct: 254 LHEKNIMHRDLKPDNILFRDFVPLKRYGLIHMGPNIMVSDFGVSSVVQEKLNVYQ----- 308 Query: 638 RSGVTGTDGWIAPEMINGERTTT-----SIDIFSLGCVFYYVLSKGQHPFGDVLRRQANI 692 TGT G++APE+ E T DIFSLGC+ YY+L G+ F + +QAN+ Sbjct: 309 ---YTGTPGYMAPEVFETETDPTKTYNEKCDIFSLGCILYYLLI-GKPLFAN---KQANM 361 Query: 693 LTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILK 737 + +D + + +L++ M+S P+ RP C+ IL+ Sbjct: 362 ---EMKIDWMGVEQELNSSHSLTMLLQKMLSPSPNDRPSCKEILE 403 >UniRef50_A0CDW7 Cluster: Chromosome undetermined scaffold_17, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_17, whole genome shotgun sequence - Paramecium tetraurelia Length = 397 Score = 84.6 bits (200), Expect = 1e-14 Identities = 60/188 (31%), Positives = 103/188 (54%), Gaps = 12/188 (6%) Query: 544 DKQFRYIALELCSATLQDY-VEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPH 602 D+ YI TL +Y V+ LN ++ + E++R+ +GL+HLH++ I+HRD+K Sbjct: 182 DQSVIYIMPHCKGGTLYEYLVQNDLNLP-ELVTQEMMRKLLIGLNHLHNIGIMHRDIKLD 240 Query: 603 NVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSI 662 N++L + +R M DFG S +N S+ R GT G+IAPE++N + Sbjct: 241 NIMLLRKNDPNSIRIM--DFGYSTLINDEMFSYQR----CGTPGYIAPEILNMGQYNQLC 294 Query: 663 DIFSLGCVFYYVLSKGQHPFGDVLRRQANIL--TGDYNLDHLDKILPEEELVVIKILIRA 720 DI+SLGCVF+ +L+ G+ + +A+ L ++ L +I L +++ +I A Sbjct: 295 DIYSLGCVFHALLT-GKKLYNTPKSTKASELLQLNRNSITSLSQICNLNALELLQSMI-A 352 Query: 721 MISAKPSA 728 ++ +PSA Sbjct: 353 IVKYRPSA 360 >UniRef50_A0CA86 Cluster: Chromosome undetermined scaffold_160, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_160, whole genome shotgun sequence - Paramecium tetraurelia Length = 569 Score = 84.6 bits (200), Expect = 1e-14 Identities = 66/295 (22%), Positives = 135/295 (45%), Gaps = 19/295 (6%) Query: 471 EGEMKIGKITFQTDQVLGKGCEGTFV--YRGTFDKRDVAVKRLLPECFT-FADREVALLR 527 E + K+ + + LGKG G Y + + K L + DRE+ +L Sbjct: 2 EQDQKVEDFVIKKSEFLGKGQYGVVYGCYSEKLKDQKLCAKVLQAQIEKGLIDREIKILE 61 Query: 528 ESDA--HAHVVRYYCTERDKQFRYIALELCSA-----TLQDYVEKKLNFECKIDSVEILR 580 + + + ++V+ Y ++++ YI +E C+ + Y K +F + +I R Sbjct: 62 QLNKVDNPNLVKIYRVIKEERQIYIVMERCTGGDLKQLMDQYQLSKKSFTLE-QIQDIAR 120 Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640 Q +G L + ++HRD+KP N+L+ +G G++ ++DFG+ + L+ ++ + Sbjct: 121 QIILGYKSLFDIKVIHRDIKPANILIE-NNGNGQIIVKLTDFGMGRMLD--DITKKQVLT 177 Query: 641 VTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-----GDVLRRQANILTG 695 GT + AP++ ++ ++ D++SLG + Y + + PF ++ + ++ Sbjct: 178 KVGTPAYAAPQLYLEDQYSSKCDVYSLGVILYQLAFNNRLPFTAKTIPELTQFLKDLKVK 237 Query: 696 DYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMFWCKQSILNF 750 + L + P++ I+ LI M+ ARP + +LK +F NF Sbjct: 238 PFQCPELTQEGPQQTKKAIQSLINKMMQFSEEARPGWDDLLKSELFEMPAKPSNF 292 >UniRef50_Q4PCB9 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 1673 Score = 84.6 bits (200), Expect = 1e-14 Identities = 83/275 (30%), Positives = 135/275 (49%), Gaps = 24/275 (8%) Query: 479 ITFQTDQVLGKGCEGTFVYRGTF--DKRDVAVKRLLPECFTFAD-----REVALLRESDA 531 +T+Q +G+G G+ VYR R VAVKR+ E T + EV LL+ S Sbjct: 958 VTYQLGNCIGRGQFGS-VYRALNLNSGRMVAVKRIKLEGRTDEEINDLMGEVDLLK-SLT 1015 Query: 532 HAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLH 590 H VV+Y R I LE + +L ++ NF K+ + +++ GL++LH Sbjct: 1016 HPSVVKYEGLVRGPDVVSIILEFVENGSLLHTLKAFGNFPEKLVASYVVK-ILEGLNYLH 1074 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650 ++VH D+K N+L + G V+ +SDFG+S L + ++ GT W+AP Sbjct: 1075 GQNVVHCDLKAANILTTKQ---GNVK--LSDFGVSLNLKAVK-KMGNKNDAIGTPNWMAP 1128 Query: 651 EMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEE 710 E+I + TT+ DI+SLGC +L+ G+ P+ D+L A + D I PE+ Sbjct: 1129 EVIELKGVTTAADIWSLGCTIIELLT-GKPPYYDMLAMSAMFRIVE---DDCPPI-PEKC 1183 Query: 711 LVVIKILIRAMISAKPSARPPCETILKYPMFWCKQ 745 ++ L+ + P+ RP E + ++ W +Q Sbjct: 1184 SDALRDLLMQCFNKDPAKRPSAEMLFEHE--WMQQ 1216 >UniRef50_Q9CEF5 Cluster: Probable serine/threonine-protein kinase pknB; n=4; Lactococcus lactis|Rep: Probable serine/threonine-protein kinase pknB - Lactococcus lactis subsp. lactis (Streptococcus lactis) Length = 627 Score = 84.6 bits (200), Expect = 1e-14 Identities = 63/221 (28%), Positives = 107/221 (48%), Gaps = 22/221 (9%) Query: 466 LMEIGEGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVAL 525 + EIG G M + D LG V R F+ D+A+ R E F A+ Sbjct: 15 IKEIGRGGM--ANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAEL---- 68 Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATM 584 +H ++V + +YI +E TL+ Y+ + +++EI+ + Sbjct: 69 -----SHPNIVGISDVGEFESQQYIVMEFVDGMTLKQYINQNAPL-ANDEAIEIITEILS 122 Query: 585 GLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGT 644 + HS I+HRD+KP NVL+S SGT ++DFG++K L+ S ++ + + G+ Sbjct: 123 AMDMAHSHGIIHRDLKPQNVLVS-SSGT----VKVTDFGIAKALS--ETSLTQTNTMFGS 175 Query: 645 DGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GD 684 +++PE G T DI+++G + + +L+ GQ PF GD Sbjct: 176 VHYLSPEQARGSNATVQSDIYAIGIILFELLT-GQIPFDGD 215 >UniRef50_Q39008 Cluster: Mitogen-activated protein kinase kinase kinase 1; n=7; Magnoliophyta|Rep: Mitogen-activated protein kinase kinase kinase 1 - Arabidopsis thaliana (Mouse-ear cress) Length = 608 Score = 84.6 bits (200), Expect = 1e-14 Identities = 83/274 (30%), Positives = 128/274 (46%), Gaps = 34/274 (12%) Query: 480 TFQTDQVLGKGCEGTFVYRGTFDKRDV-AVKRL--------LPECFTFADREVALLRESD 530 ++Q Q+LG+G G+ VY G D AVK + EC + E+ LL + Sbjct: 332 SWQKGQLLGRGSFGS-VYEGISGDGDFFAVKEVSLLDQGSQAQECIQQLEGEIKLLSQLQ 390 Query: 531 AHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEIL--RQATMGLSH 588 H ++VRY T +D YI LEL T ++ ++ + DSV L RQ GL + Sbjct: 391 -HQNIVRYRGTAKDGSNLYIFLEL--VTQGSLLKLYQRYQLR-DSVVSLYTRQILDGLKY 446 Query: 589 LHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWI 648 LH +HRD+K N+L+ G V+ ++DFGL+K F+ GT W+ Sbjct: 447 LHDKGFIHRDIKCANILV---DANGAVK--LADFGLAKV-----SKFNDIKSCKGTPFWM 496 Query: 649 APEMINGERTT---TSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKI 705 APE+IN + + + DI+SLGC + + GQ P+ D+ QA G L Sbjct: 497 APEVINRKDSDGYGSPADIWSLGCTVLEMCT-GQIPYSDLEPVQALFRIGRGTLPE---- 551 Query: 706 LPEEELVVIKILIRAMISAKPSARPPCETILKYP 739 +P+ + ++ I + P RP +L +P Sbjct: 552 VPDTLSLDARLFILKCLKVNPEERPTAAELLNHP 585 >UniRef50_UPI0000499655 Cluster: protein kinase; n=2; Entamoeba histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba histolytica HM-1:IMSS Length = 1240 Score = 84.2 bits (199), Expect = 2e-14 Identities = 57/205 (27%), Positives = 106/205 (51%), Gaps = 9/205 (4%) Query: 484 DQVLGKGCEGTFVYRGTFDKRDVAVKRLLP-----ECFTFADREVALLRESDAHAHVVRY 538 ++ +G+G G V++GT+ R VA+K+L + T ++E +L + + + Y Sbjct: 974 EKKIGEGSFGV-VFKGTYRGRVVAIKKLKESQSSEKALTEFEKEATMLDKFRSDYIIHFY 1032 Query: 539 YCTERDKQFRYIALELCSATLQDYVEKKL-NFECKIDSVEILRQATMGLSHLHSMDIVHR 597 + + +L+D +EK+ N+ ++IL A+ G+ +LH +++HR Sbjct: 1033 GAIFIPNKICLVTEYAYYGSLRDLIEKRSRNYVSHHLRLKILLDASKGIQYLHENEMLHR 1092 Query: 598 DVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGER 657 D+KP NVL+ + A ++DFG S+ +N+ + + GV GT ++APE++N + Sbjct: 1093 DIKPDNVLVLSLDDNVNINAKLTDFGSSRNVNLLMTNMTFTKGV-GTPSYMAPEILNRLK 1151 Query: 658 TTTSIDIFSLGCVFYYVLSKGQHPF 682 DI+S G Y VL+ + PF Sbjct: 1152 YKMPADIYSFGMTMYSVLNWSE-PF 1175 >UniRef50_A2RRW8 Cluster: LOC100037118 protein; n=1; Xenopus laevis|Rep: LOC100037118 protein - Xenopus laevis (African clawed frog) Length = 358 Score = 84.2 bits (199), Expect = 2e-14 Identities = 49/166 (29%), Positives = 91/166 (54%), Gaps = 8/166 (4%) Query: 574 DSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRV 633 D V ++RQ G+ HLH+ ++VH D+KP N+LL+ + G++R I DFGLS++++ Sbjct: 125 DVVRLIRQILQGVLHLHTCNVVHLDLKPQNILLTSSNPLGDIR--IVDFGLSRRVD---- 178 Query: 634 SFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANIL 693 + + GT ++APE++N E +T+ D++S+G V YV+ G PF +++ + Sbjct: 179 TIKEVREILGTPEYVAPEVLNYEPISTATDMWSVG-VLAYVMLTGVSPFQGETKQETFLN 237 Query: 694 TGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739 N+ + + + I I++++ P R + LK+P Sbjct: 238 ISQVNIQYGQEDFEGISDLAID-FIKSLLIKNPRKRIRADQCLKHP 282 >UniRef50_A7IE03 Cluster: Protein kinase; n=1; Xanthobacter autotrophicus Py2|Rep: Protein kinase - Xanthobacter sp. (strain Py2) Length = 586 Score = 84.2 bits (199), Expect = 2e-14 Identities = 63/210 (30%), Positives = 104/210 (49%), Gaps = 17/210 (8%) Query: 481 FQTDQVLGKGCEG-TFVYRGTFDKRDVAVKRLLPECF---TFADR---EVALLRESDAHA 533 ++ +LG G G R T R+VA+K L PE +F DR E + L + H Sbjct: 12 YEITALLGSGGNGRVHAARDTMLGREVAIKSLRPELMNDASFLDRFRAEASSLARLN-HP 70 Query: 534 HVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592 ++ Y + + Y+ +EL TL+ ++++ + + I+ Q GL++ HSM Sbjct: 71 NIATLYALQPEGSNLYMIMELVRGRTLESVLQQRGGPLPVQECLAIVAQVADGLAYAHSM 130 Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652 ++HRD+KP N+++ T + R I DFG+++ G +R + GT +IAPE Sbjct: 131 GVIHRDIKPSNLMI-----TDDGRVKIMDFGIARV--AGSQRLTRDGSIIGTLAYIAPEQ 183 Query: 653 INGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 + G D++SL V Y +LS G PF Sbjct: 184 LRGSPGDERSDLYSLAIVVYEMLS-GAPPF 212 >UniRef50_A6CG99 Cluster: Serine/threonine protein kinase; n=1; Planctomyces maris DSM 8797|Rep: Serine/threonine protein kinase - Planctomyces maris DSM 8797 Length = 499 Score = 84.2 bits (199), Expect = 2e-14 Identities = 70/227 (30%), Positives = 110/227 (48%), Gaps = 20/227 (8%) Query: 466 LMEIGEGEMKIGKIT-FQTDQVLGKGCEGTFVYRG--TFDKRDVAVKRLLPECFTFADRE 522 L+E E + +G+ ++ LG+G G V RG T R A+K L P + A Sbjct: 86 LLEPTERQDSLGRFAQYEILDFLGRGGMG-IVMRGLDTALDRQCAIKVLAPRFASSAAAR 144 Query: 523 VALLRESDA-----HAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSV 576 RE+ + H HVV ++ + + +LQ +E+ I+S+ Sbjct: 145 KRFSREAKSAAAVVHPHVVPILTVNEHNGLPFLVMPVVEGQSLQRRIEEYGPLSV-IESI 203 Query: 577 EILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEV-RAMISDFGLSKKLNIGRVSF 635 I Q GL+ H+ +VHRD+KP N+LL EV R I+DFGL++ I S Sbjct: 204 RIAAQVADGLAAAHTQGLVHRDIKPENILLE-----HEVERVQITDFGLARA--IDDASM 256 Query: 636 SRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 +R + GT +++PE +G+ D+FSLG V Y++L+ G+ PF Sbjct: 257 TRSGVIAGTPQYMSPEQAHGDSIDHRSDLFSLGSVMYFMLA-GRSPF 302 >UniRef50_Q9SA26 Cluster: F3O9.7 protein; n=3; Arabidopsis thaliana|Rep: F3O9.7 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 1147 Score = 84.2 bits (199), Expect = 2e-14 Identities = 76/259 (29%), Positives = 124/259 (47%), Gaps = 25/259 (9%) Query: 487 LGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLR-----ESDA-----HAHVV 536 LG G GT VY G + DVA+KR+ CF E L E++ H +VV Sbjct: 869 LGSGTFGT-VYHGKWRGSDVAIKRIKKSCFAGRSSEQERLTGEFWGEAEILSKLHHPNVV 927 Query: 537 RYYCTERDKQFRYIALE---LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMD 593 +Y +D +A + +L+ + +K + + I A G+ +LH+ + Sbjct: 928 AFYGVVKDGPGATLATVTEYMVDGSLRHVLVRKDRHLDRRKRLIIAMDAAFGMEYLHAKN 987 Query: 594 IVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI 653 IVH D+K N+L+++ + + + DFGLSK VS GV GT W+APE++ Sbjct: 988 IVHFDLKCDNLLVNLKDPSRPI-CKVGDFGLSKIKRNTLVS----GGVRGTLPWMAPELL 1042 Query: 654 NGERTTTS--IDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEEL 711 NG + S +D+FS G V + +L+ G+ P+ ++ I+ G N + L +P Sbjct: 1043 NGSSSKVSEKVDVFSFGIVLWEILT-GEEPYANM--HYGAIIGGIVN-NTLRPTIPSYCD 1098 Query: 712 VVIKILIRAMISAKPSARP 730 +IL+ + P+ARP Sbjct: 1099 SDWRILMEECWAPNPTARP 1117 >UniRef50_Q86HN7 Cluster: Similar to Asterina pectinifera (Starfish). Polo-like kinase; n=2; Dictyostelium discoideum|Rep: Similar to Asterina pectinifera (Starfish). Polo-like kinase - Dictyostelium discoideum (Slime mold) Length = 978 Score = 84.2 bits (199), Expect = 2e-14 Identities = 62/222 (27%), Positives = 112/222 (50%), Gaps = 25/222 (11%) Query: 526 LRESDAHAHVVRY-YCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATM 584 + S +H ++V++ +C E ++ YI LELC+ + KK + + ++ + Q M Sbjct: 214 IHSSLSHENIVKFEHCFENEENV-YILLELCNQKTVMDIHKKRKYLMEYETKYYVYQVIM 272 Query: 585 GLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGT 644 + +LH+ +I+HRD+K N+ + +R + DFGLS K+ G R+ + GT Sbjct: 273 AVQYLHNNNIIHRDLKLGNLFID------NMRIKLGDFGLSTKVEHG----ERKKTICGT 322 Query: 645 DGWIAPEMI-NGERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDH 701 +IAPE++ N + +D++S+G + Y +L G+ PF DV I Y+ Sbjct: 323 PNYIAPEILDNSNGHSYEVDVWSIGIILYTLLI-GKPPFETSDVKHTYQRIKQNQYS--- 378 Query: 702 LDKILPEEELV--VIKILIRAMISAKPSARPPCETILKYPMF 741 P+E ++ K LI ++++ P RP IL++ F Sbjct: 379 ----FPDEPIISHYGKSLIISILNPVPEQRPNLTQILEHDFF 416 >UniRef50_Q22W86 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 596 Score = 84.2 bits (199), Expect = 2e-14 Identities = 65/255 (25%), Positives = 133/255 (52%), Gaps = 28/255 (10%) Query: 478 KITFQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRL-LPECFTFADR---EVALLRESDA 531 K ++LG G G+ + D + +A+K++ + F D E+ LLR D Sbjct: 12 KYVVDESKLLGSGNCGSVYFGWKTDNTEQYLAIKQIPINSKFEITDSMLIEINLLRRLD- 70 Query: 532 HAHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLH 590 H ++V++ ++ K F Y+ +E C+ +++D + + E ++ ++ +Q L+ Sbjct: 71 HPNIVKFIDAKKTKDFMYLIMEFCNEGSIEDLIINQKVSENEV--LDYFKQICKAFRELN 128 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650 + +I+H DVKP N+LL + ++DFG+SK ++ S + + GT ++AP Sbjct: 129 NKNILHGDVKPSNILLH------NSQCKLADFGVSKTID----KKSENTTMRGTPFFMAP 178 Query: 651 EMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANI---LTGDYNLD----HLD 703 +++N + TT DI+SLG +++L K + P+ + +++Q + +T +Y+ D H Sbjct: 179 QLLNNQPYTTKSDIWSLGITLFFMLFK-RLPWDEKVQKQHQLRQFITNEYDPDKFFSHCT 237 Query: 704 KILPEEELVVIKILI 718 ++ E L ++K +I Sbjct: 238 NVISEFTLSLLKRMI 252 >UniRef50_A0CDN2 Cluster: Chromosome undetermined scaffold_17, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_17, whole genome shotgun sequence - Paramecium tetraurelia Length = 483 Score = 84.2 bits (199), Expect = 2e-14 Identities = 50/164 (30%), Positives = 95/164 (57%), Gaps = 10/164 (6%) Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALE-LCSATLQDYVEKKLNFECKIDSVEIL 579 +E+ ++R + H+++ + D++ Y+ L+ L L +++ K N + ++++ Sbjct: 160 KEIEIMRLMK-NKHIIKLFEVFEDEKKIYLLLDFLQGRDLLNHIYKNDNVYDETLVLKLM 218 Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNI-GRVSFSRR 638 GLS++HS +I+HRD+KP N++L + ++ +++DFGL+ N G F R Sbjct: 219 HNVLNGLSYIHSHNIIHRDIKPENLILKQKNNIEDI--ILADFGLADFYNPDGDYLFKR- 275 Query: 639 SGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 G+ G+IAPEM+N E+ +D++SLG VF+ +L+ GQ F Sbjct: 276 ---CGSIGYIAPEMLNNEKYDYKVDVYSLGTVFFLLLT-GQQAF 315 >UniRef50_Q9HFT9 Cluster: Ste11alpha protein; n=5; Tremellomycetes|Rep: Ste11alpha protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 1230 Score = 84.2 bits (199), Expect = 2e-14 Identities = 65/224 (29%), Positives = 110/224 (49%), Gaps = 17/224 (7%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEI 578 +RE+ LL+E H ++V+Y + D I LE ++ + FE + Sbjct: 988 EREIELLKELQ-HENIVQYLDSSVDANHLNIFLEYVPGGSVAALLNNYGAFEEALVR-NF 1045 Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSR- 637 +RQ GL++LH IVHRD+K N+L+ G ISDFG+SKK+ ++ R Sbjct: 1046 VRQILTGLNYLHMRGIVHRDIKGANILVDNKGG-----IKISDFGISKKVENSLITGLRT 1100 Query: 638 -RSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGD 696 R + G+ W+APE++ + DI+S+GC+ +L+ G HP+ D+ + QA Sbjct: 1101 NRPSLQGSVFWMAPEVVKQTSYSPKADIWSVGCLVVEMLT-GTHPWADLTQMQA-----I 1154 Query: 697 YNLDHLDKILPEEEL-VVIKILIRAMISAKPSARPPCETILKYP 739 + + L + P ++ V +R + + RP +LK+P Sbjct: 1155 FRIGSLARPAPPSDISVQADEFLRKTFEIEHAKRPTAAQLLKHP 1198 >UniRef50_A1CZC9 Cluster: MAP kinase kinase kinase Ste11/SteC; n=10; Eurotiomycetidae|Rep: MAP kinase kinase kinase Ste11/SteC - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 973 Score = 84.2 bits (199), Expect = 2e-14 Identities = 63/189 (33%), Positives = 91/189 (48%), Gaps = 17/189 (8%) Query: 517 TFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSV 576 T E+ LL+ H ++V+Y T D Q+ I LE + K+ N + Sbjct: 689 TALKHEIELLQGLH-HPNIVQYLGTSADDQYLNIFLEYVPGGSIATMLKQYNTFQEPLIK 747 Query: 577 EILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS 636 +RQ GLS+LHS DI+HRD+K N+L+ G ISDFG+SK++ V + Sbjct: 748 NFVRQILEGLSYLHSRDIIHRDIKGANILVDNKGG-----IKISDFGISKRVEASTVLGA 802 Query: 637 RRSG----------VTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVL 686 R SG + G+ W+APE++ T DI+SLGC+ + G HPF D Sbjct: 803 RASGSGGGHLHRPSLQGSVYWMAPEVVRQTAHTKKADIWSLGCLVVEMFI-GAHPFPDCS 861 Query: 687 RRQANILTG 695 + QA G Sbjct: 862 QLQAIFAIG 870 >UniRef50_P23561 Cluster: Serine/threonine-protein kinase STE11; n=4; Saccharomycetaceae|Rep: Serine/threonine-protein kinase STE11 - Saccharomyces cerevisiae (Baker's yeast) Length = 738 Score = 84.2 bits (199), Expect = 2e-14 Identities = 55/170 (32%), Positives = 94/170 (55%), Gaps = 9/170 (5%) Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILR 580 E+ LL+E H ++V YY ++ I LE ++ + FE + + R Sbjct: 525 EMNLLKELH-HENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLIT-NFTR 582 Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640 Q +G+++LH +I+HRD+K N+L+ + G V+ I+DFG+SKKL+ ++R+ Sbjct: 583 QILIGVAYLHKKNIIHRDIKGANILIDIK---GCVK--ITDFGISKKLSPLNKKQNKRAS 637 Query: 641 VTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQA 690 + G+ W++PE++ TT DI+S GCV + + G+HPF D + QA Sbjct: 638 LQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT-GKHPFPDFSQMQA 686 >UniRef50_P34331 Cluster: Serine/threonine-protein kinase plk-1; n=7; Bilateria|Rep: Serine/threonine-protein kinase plk-1 - Caenorhabditis elegans Length = 649 Score = 84.2 bits (199), Expect = 2e-14 Identities = 60/223 (26%), Positives = 107/223 (47%), Gaps = 17/223 (7%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEIL 579 D E L+ H ++V+ + D YI LELC+ + K+ + ++ Sbjct: 84 DNERILIHRELGHINIVKLFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEPEARYFT 143 Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639 Q G+ +LH ++I+HRD+K N+ L+ ++ I DFGL+ +N R+ Sbjct: 144 HQIVDGVLYLHDLNIIHRDMKLGNLFLN-----DDLVVKIGDFGLATTVN----GDERKK 194 Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYN- 698 + GT +IAPE++N + +DI+++GC+ Y+L GQ PF ++ L Y+ Sbjct: 195 TLCGTPNYIAPEVLNKAGHSFEVDIWAVGCIL-YILLFGQPPF------ESKSLEETYSR 247 Query: 699 LDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741 + H + +P LIR M+ +P+ RP + + + F Sbjct: 248 IRHNNYTIPSIATQPAASLIRKMLDPEPTRRPTAKQVQRDGFF 290 >UniRef50_P28829 Cluster: Protein kinase byr2; n=3; Schizosaccharomyces pombe|Rep: Protein kinase byr2 - Schizosaccharomyces pombe (Fission yeast) Length = 659 Score = 84.2 bits (199), Expect = 2e-14 Identities = 58/179 (32%), Positives = 94/179 (52%), Gaps = 12/179 (6%) Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILR 580 E+ALL+E +H H+V+Y + + I LE ++ + +FE + ++ Sbjct: 447 EIALLQEL-SHEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVK-NFIK 504 Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSF---SR 637 Q GL +LHS IVHRD+K N+L+ G+++ ISDFG+SKKL + S Sbjct: 505 QTLKGLEYLHSRGIVHRDIKGANILV---DNKGKIK--ISDFGISKKLELNSTSTKTGGA 559 Query: 638 RSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGD 696 R G+ W+APE++ T DI+SLGC+ +L+ +HP+ + + QA G+ Sbjct: 560 RPSFQGSSFWMAPEVVKQTMHTEKTDIWSLGCLVIEMLT-SKHPYPNCDQMQAIFRIGE 617 >UniRef50_UPI00015B4881 Cluster: PREDICTED: similar to serine/threonine protein kinase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to serine/threonine protein kinase - Nasonia vitripennis Length = 546 Score = 83.8 bits (198), Expect = 2e-14 Identities = 72/244 (29%), Positives = 122/244 (50%), Gaps = 34/244 (13%) Query: 502 DKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELC-SATLQ 560 DKR + +K E + ++EV + H+ V R +CT +D + Y L + L Sbjct: 100 DKRHI-IKEKKSE-YVKREKEVLNMLAGAKHSFV-RLFCTFQDLERLYFVLSYAKNGELL 156 Query: 561 DYVEKKLNF--EC-KIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRA 617 Y+ K +F EC K S EILR GL +LH + I+HRD+KP N+LL + Sbjct: 157 PYINKVGSFDIECTKFYSAEILR----GLEYLHGLGIIHRDLKPENILLDE-----NMHV 207 Query: 618 MISDFGLSK------------KLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIF 665 +I+DFG +K K N G+ RR+ GT +++PE++ + T+ + D++ Sbjct: 208 LITDFGSAKILKEDPEQLALDKTNSGKYRRERRNSFVGTAQYVSPELLTDKTTSRASDLW 267 Query: 666 SLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAK 725 +LGC+ Y +++ G PF R ++ L L L+ +P+ + + L+ ++ + Sbjct: 268 ALGCIIYQMVA-GLPPF----RSRSEYLIFQKIL-ALEYEIPDGFCELARDLVSKLLKLE 321 Query: 726 PSAR 729 PS R Sbjct: 322 PSER 325 >UniRef50_Q6BFH8 Cluster: Protein kinase, putative; n=3; Paramecium tetraurelia|Rep: Protein kinase, putative - Paramecium tetraurelia Length = 531 Score = 83.8 bits (198), Expect = 2e-14 Identities = 66/210 (31%), Positives = 109/210 (51%), Gaps = 22/210 (10%) Query: 480 TFQTDQVLGKG-CEGTFVYRGTFDKRDVAVKRLLPECFTFADR-------EVALLRESDA 531 +F+ + +GKG ++ D+R A+K E D+ E+A++R+ D+ Sbjct: 115 SFKAHRKIGKGNFASVYLADRLEDERSFAIKAFSKEVAYGQDKGKLSILNEIAIMRQLDS 174 Query: 532 HAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATM-GLSHL 589 +A + + E D Y+ L+L +L D V+ + F +E+L + + GL H+ Sbjct: 175 YALIKLHEVYETDNSL-YMVLDLLEGGSLYDKVKNRPQFNAF--EIEVLVFSLLEGLHHM 231 Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649 HS +I+HRD+KP N+L V I+DFGL+++ + F+R GT G++A Sbjct: 232 HSKNIMHRDLKPENILFRKQGVIQSV--CIADFGLAQRSDEFPYLFNR----CGTPGFVA 285 Query: 650 PEMIN---GERTTTSIDIFSLGCVFYYVLS 676 PE+IN G R DIFSLG +FY +L+ Sbjct: 286 PEVINCKDGGRYDPICDIFSLGLIFYILLT 315 >UniRef50_Q5DBY2 Cluster: SJCHGC06342 protein; n=1; Schistosoma japonicum|Rep: SJCHGC06342 protein - Schistosoma japonicum (Blood fluke) Length = 324 Score = 83.8 bits (198), Expect = 2e-14 Identities = 64/225 (28%), Positives = 105/225 (46%), Gaps = 15/225 (6%) Query: 521 REVALLRESDAHAHVVR---YYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSV 576 +E+ +++ ++H+V+ YY E++ + LE CS L YV + + Sbjct: 75 QEIDIMKTGHYNSHIVKMKHYYIGEKEV---VLLLENCSHGDLYHYVHYSEEPLPENIVI 131 Query: 577 EILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFS 636 E+L Q LS +HS IVH D+KP N+LL P ++ + DFGL+K L V Sbjct: 132 EVLWQLLKALSFIHSQSIVHLDIKPENILLRRPLPHCDI--ALCDFGLAKYLRTNEVI-- 187 Query: 637 RRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGD 696 + GT + APE++N + + DI+S+G V YY+L+ + PF D + + Sbjct: 188 --RDLVGTPDYAAPEVLNYDPIHLTTDIWSVGVVVYYLLT-SESPFWDESKEHTYLNVCQ 244 Query: 697 YNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741 + + D + + I I+ +I P RP L P F Sbjct: 245 LKISYPDYLFHNISVEAI-AFIKRLIQRNPKDRPSAIDCLDDPWF 288 >UniRef50_A0E054 Cluster: Chromosome undetermined scaffold_71, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_71, whole genome shotgun sequence - Paramecium tetraurelia Length = 553 Score = 83.8 bits (198), Expect = 2e-14 Identities = 60/205 (29%), Positives = 105/205 (51%), Gaps = 22/205 (10%) Query: 484 DQVLGKGCEGTFVYRGTFDKRD----VAVKRL-------LPECFTFADREVALLRESDAH 532 +++LGKG GT VY G D +AVK + P+ RE +L+ + H Sbjct: 17 NKILGKGTYGT-VYLGYMDTGQNQVRIAVKTVPMDSVKQSPQILNLIKRESTILKAVE-H 74 Query: 533 AHVVRYYCTERDKQFRYIALELC-SATLQDYV-EKKLNFECKIDSVEILRQATMGLSHLH 590 ++VR Y R + + YI LE C L+ ++ KK +++++ L+ G L Sbjct: 75 PNIVRLYNANRTQNYIYIFLEFCPDGDLRKFMLSKKEKHLSELEAIIFLKHIVEGFKELF 134 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650 I+HRD+KP N+LLS +G A I+DFG ++ + + + + GT +++P Sbjct: 135 QKKIIHRDIKPENILLS--NGI----AKIADFGFARVMEV-EMDEPGKFSRNGTPIYMSP 187 Query: 651 EMINGERTTTSIDIFSLGCVFYYVL 675 +++ G+ + D++SLG +FY +L Sbjct: 188 QILRGQPFSAKCDVWSLGIMFYEML 212 >UniRef50_A0D467 Cluster: Chromosome undetermined scaffold_37, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_37, whole genome shotgun sequence - Paramecium tetraurelia Length = 835 Score = 83.8 bits (198), Expect = 2e-14 Identities = 75/247 (30%), Positives = 122/247 (49%), Gaps = 26/247 (10%) Query: 496 VYRGTFDKRDVAVKRL---LPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIAL 552 VY GT+ VAVK L +P +REV +L + H ++V+Y + + YI + Sbjct: 57 VYLGTYKSMQVAVKVLEKSVPCYCELFNREVEILEQLQ-HPNLVKYITSYETFEKLYIVM 115 Query: 553 ELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGT 612 + + + K E KI S I++Q + L++LH+ DI HRD+KP N+L+ + Sbjct: 116 DYVEGSNLTELSKSNLSEQKIRS--IIKQLLIVLTYLHNKDITHRDIKPDNILVGL---D 170 Query: 613 GEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFY 672 G VR + DFGLS++ + ++S+ + GT ++APEMI S+D++S+G + Sbjct: 171 GRVR--LIDFGLSQQ-SESKISYDK----CGTLLFMAPEMILKMPYLKSVDMWSIG-IIQ 222 Query: 673 YVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPC 732 Y+L + +HPF +I T + N +DK R + P AR Sbjct: 223 YLLYERKHPF-HYENLVESIQTYNINFSIMDKSAQN--------FFRKCAAVNPEARMSA 273 Query: 733 ETILKYP 739 E L +P Sbjct: 274 EQALMHP 280 >UniRef50_O15865 Cluster: Calcium-dependent protein kinase 2; n=2; Plasmodium falciparum|Rep: Calcium-dependent protein kinase 2 - Plasmodium falciparum (isolate K1 / Thailand) Length = 513 Score = 83.8 bits (198), Expect = 2e-14 Identities = 68/209 (32%), Positives = 113/209 (54%), Gaps = 20/209 (9%) Query: 484 DQVLGKGCEGTFVYRGTFDK---RDVAVKRLLPECFTFADR---EVALLRESDAHAHVVR 537 D+ LG+G G VY+G DK + A+K + +R E+ ++++ D H ++V+ Sbjct: 75 DEKLGQGTYGC-VYKG-IDKVTNQLYAIKEEKKDRLKNINRFFQEIEIMKKLD-HPNIVK 131 Query: 538 YYCTERDKQFRYIALELCSAT-LQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVH 596 Y T + + Y+ +ELCS L D + + +F K ++ I++Q + +LHS++IVH Sbjct: 132 LYETYENDNYIYLIMELCSGRELFDSIIENGSFTEK-NAATIMKQIFSAIFYLHSLNIVH 190 Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656 RD+KP N L S + I DFGLSK L G + ++ GT ++AP++++G Sbjct: 191 RDLKPENFLFQ--SENKDSLLKIIDFGLSKNLGTGEFTTTK----AGTPYYVAPQVLDG- 243 Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPF-GD 684 + DI+S G + Y +L G PF GD Sbjct: 244 KYDKKCDIWSSGVIMYTLLC-GYPPFYGD 271 >UniRef50_UPI00015B60DA Cluster: PREDICTED: similar to calcium/calmodulin dependent protein kinase I; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to calcium/calmodulin dependent protein kinase I - Nasonia vitripennis Length = 443 Score = 83.4 bits (197), Expect = 3e-14 Identities = 55/172 (31%), Positives = 94/172 (54%), Gaps = 12/172 (6%) Query: 532 HAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLH 590 H ++V+ T DK Y+ +EL + L D + +K ++ + D+ ++RQ + ++H Sbjct: 100 HPNIVQLLETFEDKHKVYLVMELVTGGELFDRIVEKGSYTER-DASSLIRQVLEAVDYMH 158 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650 +VHRD+KP N+L P ++ MISDFGLSK + G ++ + GT G++AP Sbjct: 159 EQGVVHRDLKPENLLYYSPDEDSKI--MISDFGLSKMEDSGIMATA-----CGTPGYVAP 211 Query: 651 EMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGDYNLD 700 E++ + ++D++S+G V Y+L G PF D A IL G++ D Sbjct: 212 EVLAQKPYGKAVDVWSIG-VISYILLCGYPPFYDENDANLFAQILKGEFEFD 262 >UniRef50_UPI0000E7FBCB Cluster: PREDICTED: similar to NIMA (never in mitosis gene a)-related kinase 5; n=1; Gallus gallus|Rep: PREDICTED: similar to NIMA (never in mitosis gene a)-related kinase 5 - Gallus gallus Length = 816 Score = 83.4 bits (197), Expect = 3e-14 Identities = 71/264 (26%), Positives = 126/264 (47%), Gaps = 27/264 (10%) Query: 487 LGKGCEGT-FVYRGTFDKRDVAVKRL----LPECFTFADREVALLRESDAHAHVVRYYCT 541 +G+G G F+ + D +K + +P A ++ +L HA++V +Y + Sbjct: 10 IGEGSFGKIFLAKAKVDNEQCVIKEIDLTKMPVKEKEASQKEVILLAKMKHANIVTFYAS 69 Query: 542 ERDKQFRYIALELCSATLQDYVEKKLNFECKI--DSVEILR---QATMGLSHLHSMDIVH 596 +++ YI +E C D + K++N + + + +IL Q +GL H+H I+H Sbjct: 70 LQEENKLYIVMEYCDGG--DLM-KRINMQHGVLFEEDQILSWFVQIALGLKHIHDRKILH 126 Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656 RD+K N+ L S G+V A + DFG++++LN F+ GT +++PE+ Sbjct: 127 RDIKSQNIFL---SSNGKV-AKLGDFGIARQLN-DTTEFAYT--CVGTPYYLSPEICENR 179 Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPF-GDVLRRQANILTGDYNLDHLDKILPEEELVVIK 715 DI+SLGCV Y + + +HPF G+ L + + Y + P ++ Sbjct: 180 PYNNKTDIWSLGCVLYELCAL-KHPFEGNSLHQLVLKICRGY----FHPVSPNYS-YDLR 233 Query: 716 ILIRAMISAKPSARPPCETILKYP 739 +LI + P RP +IL+ P Sbjct: 234 MLISQLFKISPRDRPSITSILRKP 257 >UniRef50_UPI00006CF367 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 529 Score = 83.4 bits (197), Expect = 3e-14 Identities = 55/184 (29%), Positives = 96/184 (52%), Gaps = 11/184 (5%) Query: 500 TFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALE-LCSAT 558 TFDKR + + + T E+ +LR+ D H ++++ Y + Y+ L Sbjct: 107 TFDKRALLTSKNSEKTRTGLLNEIQILRKCD-HPNIIKLYEVYESDNYIYLVQNVLKGGE 165 Query: 559 LQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAM 618 L D + K NF K ++ +I+ Q L ++H+ +I+HRD+KP N++L S +++ Sbjct: 166 LFDTIIKNGNFSEK-NAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDFQIK-- 222 Query: 619 ISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKG 678 ++DFGL+ + F R GT G++APE++ ++ +D+FS G V Y+L G Sbjct: 223 LADFGLA-AFTSDDLLFKR----CGTPGYVAPEILEDKKYDQKVDVFSSG-VILYILLTG 276 Query: 679 QHPF 682 PF Sbjct: 277 CSPF 280 >UniRef50_Q2S2K2 Cluster: Protein kinase domain; n=1; Salinibacter ruber DSM 13855|Rep: Protein kinase domain - Salinibacter ruber (strain DSM 13855) Length = 649 Score = 83.4 bits (197), Expect = 3e-14 Identities = 75/265 (28%), Positives = 128/265 (48%), Gaps = 28/265 (10%) Query: 481 FQTDQVLGKGCEGTFVYRGTFD--KRDVAVKRLLPECF---TFADR---EVALLRESDAH 532 ++ D V+G+G GT VYR T ++ VA+K + P TF R E L DA Sbjct: 11 YRLDAVIGRGGMGT-VYRATDQALEKTVALKVIAPHLADDDTFVRRFREEAKALARLDAD 69 Query: 533 AHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592 V Y E ++ ++ + +L+ + ++ E ++ +LRQ + H H+ Sbjct: 70 GIVDVYTLRETEEALFFVMEHVEGPSLETVLRRRGQLEPP-QALSLLRQVLTAVGHAHAS 128 Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652 ++HRD+KP N+L+ + +A+I+DFGL+K L + GT +++PE Sbjct: 129 GVLHRDLKPSNILID-----ADGQAVITDFGLAKIL-ASDADLTATHDQLGTVAYMSPEQ 182 Query: 653 ING-ERTTTSIDIFSLGCVFYYVLSKGQHPF---GDVLRRQANILTGDY--NLDHLDKIL 706 + G + + D+F++G + Y VL+ G+ PF G Q I+ + H ++ Sbjct: 183 VKGLQNVDAASDLFAVGLLAYEVLT-GRLPFDRSGSDFVVQRAIVDASFPPPSTHAPEVP 241 Query: 707 PEEELVVIKILIRAMISAKPSARPP 731 P E VV+ +L S P+ARPP Sbjct: 242 PAVEQVVLDLL-----SKDPAARPP 261 >UniRef50_Q4UF19 Cluster: Serine/threonine protein kinase, putative; n=2; Theileria|Rep: Serine/threonine protein kinase, putative - Theileria annulata Length = 1124 Score = 83.4 bits (197), Expect = 3e-14 Identities = 65/220 (29%), Positives = 109/220 (49%), Gaps = 17/220 (7%) Query: 545 KQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHN 603 K+ +I +E C +L + + K+ + ++ RQ LS++H I+HRDVKP N Sbjct: 389 KKCLFILMEYCGEESLFETINKQTLQDTPQKVTDLFRQIMEALSYIHEKGIIHRDVKPSN 448 Query: 604 VLLSMPSGTGEVRAMISDFGLSKKL--NIGRVSFSRRSGVTGTDGWIAPEMINGERTTTS 661 + L + E+ + DFGL+ KL + G+ + +GV GT ++APE + Sbjct: 449 IFLKFEN---EITIKLGDFGLTAKLQQSKGKNTIVNENGVVGTLHYMAPEQFECDAYNEK 505 Query: 662 IDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPE--EELVVIKI--L 717 +DI+S G V + +LSK PF + R IL+ + +K PE E V ++ L Sbjct: 506 VDIYSAGVVLFEMLSK---PFQTFMER-CEILS---SFSTPNKQWPEGFRERVDNRLFKL 558 Query: 718 IRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQ 757 + +M++ P+ RP IL+ +F + L L +V Q Sbjct: 559 LESMLNINPNKRPSASEILQNEIFTSNKLNLQSLYNVITQ 598 >UniRef50_A5K3W6 Cluster: Serine/threonine protein kinase, putative; n=1; Plasmodium vivax|Rep: Serine/threonine protein kinase, putative - Plasmodium vivax Length = 1526 Score = 83.4 bits (197), Expect = 3e-14 Identities = 49/158 (31%), Positives = 88/158 (55%), Gaps = 12/158 (7%) Query: 544 DKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPH 602 ++++ YI +E C TL++ ++ ++ + E+++Q GL ++H M+I+HRD+KP Sbjct: 590 NEKYLYILMEYCPGKTLREAIDCGFIYKNENLLWELIKQILKGLHYIHDMNIMHRDIKPS 649 Query: 603 NVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSI 662 N+ L + + A I DFGL+ +++ + + + GT +I+PE +NGE Sbjct: 650 NIFLQISDNI--LTAKIGDFGLTTRIDNNSNNINPSA---GTVNYISPEQLNGEHFDQKA 704 Query: 663 DIFSLGCVFYYVLSKGQHPFGDVLRRQ---ANILTGDY 697 DIFSLG VF+ + PF ++ R +N+L G Y Sbjct: 705 DIFSLGVVFFEMF---HEPFSTLMERSIVLSNLLKGIY 739 >UniRef50_A0DFE9 Cluster: Chromosome undetermined scaffold_49, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_49, whole genome shotgun sequence - Paramecium tetraurelia Length = 445 Score = 83.4 bits (197), Expect = 3e-14 Identities = 77/262 (29%), Positives = 129/262 (49%), Gaps = 30/262 (11%) Query: 481 FQTDQVLGKGCEGTFVYRGTF--DKRDVAVKRLLPECFTFADREVALLRESDA-----HA 533 + ++GKG G VY+ +K + AVK A+LRE D H Sbjct: 116 YSIGNLIGKGTYGK-VYKAIQKQNKSEYAVKTFDKSNLQKQIEIEAILREIDILRIVQHP 174 Query: 534 HVVRYYCTERDKQFRYIALELCSA-TLQDYV-EKKLNFECKIDSVEILRQATMGLSHLHS 591 V++ T + ++ EL L+ + EKKLN + V I+ + L+++HS Sbjct: 175 RVIKLLETYESETHIFVVYELLKGGELKQLMNEKKLNQD---QCVSIIYKIIDALAYIHS 231 Query: 592 MDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNI-GRVSFSRRSGVTGTDGWIAP 650 I+HRD+KP N++ ++ +I+DFGL+ G+ FSR GT G++AP Sbjct: 232 KGIIHRDLKPENLIFRYAQNIEDI--VIADFGLADFYRKDGKYLFSR----CGTAGYLAP 285 Query: 651 EMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV---LRRQANILTGDYNLDHLDKILP 707 E+I + +D++S+G VFY +++ G+ PF + + Q N+L+ N+D L K++ Sbjct: 286 ELIMNKIYDYKVDVYSVGIVFYMLINGGKSPFEKIDYATQLQQNMLS---NID-LKKLII 341 Query: 708 EEELVVIKILIRAMISAKPSAR 729 E + L+ MI A P +R Sbjct: 342 SNE---CQDLLSKMIDANPQSR 360 >UniRef50_A0CJV4 Cluster: Chromosome undetermined scaffold_2, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_2, whole genome shotgun sequence - Paramecium tetraurelia Length = 465 Score = 83.4 bits (197), Expect = 3e-14 Identities = 60/198 (30%), Positives = 105/198 (53%), Gaps = 16/198 (8%) Query: 549 YIALELCSA-TLQDYVEKKLNFECKIDSVE-ILRQATMGLSHLHSMDIVHRDVKPHNVLL 606 YI LE C +L Y+ K+L + + ++ IL + G+++LHS++I+HRD+KP N++L Sbjct: 187 YIVLEYCRGQSLNSYI-KELKHQLNVRIIQNILWELLQGVAYLHSLNIIHRDIKPENIIL 245 Query: 607 SMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSI--DI 664 ++ ++ I DFGLS KL ++ GT G++APE+IN + + DI Sbjct: 246 NIQE--KKIDLKIVDFGLSVKLEP-----NKELKKCGTPGYVAPEIINLKNGKYGLESDI 298 Query: 665 FSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYN-LDHLDKILPEEELVVIKILIRAMIS 723 FS+GCVFY +L + +G+ Q IL+ + L ++ + + + L+ M+ Sbjct: 299 FSVGCVFYKLLLRKDLFYGET---QNEILSANRRCLCNIQNLSLIHIPITAQNLLSEMLQ 355 Query: 724 AKPSARPPCETILKYPMF 741 P R + L++ F Sbjct: 356 EDPRLRIKATSALQHHFF 373 >UniRef50_UPI0000F20581 Cluster: PREDICTED: similar to Endoplasmic reticulum (ER) to nucleus signalling 2; n=1; Danio rerio|Rep: PREDICTED: similar to Endoplasmic reticulum (ER) to nucleus signalling 2 - Danio rerio Length = 111 Score = 83.0 bits (196), Expect = 4e-14 Identities = 35/43 (81%), Positives = 39/43 (90%) Query: 659 TTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDH 701 T+++DIFS GCVFYYV SKGQHPFGD LRRQANIL+G YNLDH Sbjct: 9 TSAVDIFSAGCVFYYVTSKGQHPFGDTLRRQANILSGVYNLDH 51 >UniRef50_Q182R7 Cluster: Serine/threonine-protein kinase and phosphatase; n=2; Clostridium difficile|Rep: Serine/threonine-protein kinase and phosphatase - Clostridium difficile (strain 630) Length = 669 Score = 83.0 bits (196), Expect = 4e-14 Identities = 57/188 (30%), Positives = 97/188 (51%), Gaps = 15/188 (7%) Query: 504 RDVAVKRLLPECFTFADREVALLRESDA-----HAHVVRYYCTERDKQFRYIALELCSA- 557 R VA+K L PE + RE++A H ++V Y D + YI +E Sbjct: 34 RTVALKVLRPEFVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGK 93 Query: 558 TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRA 617 L++ ++ + + + +++I +Q M LS H I+HRD+KPHN+L+ S G V Sbjct: 94 NLKEIIQDEGILD-EYTALDITKQIAMALSAAHKKGIIHRDIKPHNILI---SNEGRV-V 148 Query: 618 MISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSK 677 ++DFG++K + + + + G+ + +PE G+ T + D++SLG V Y +L Sbjct: 149 KVADFGIAKA--VSNSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLI- 205 Query: 678 GQHPF-GD 684 G+ PF GD Sbjct: 206 GKVPFRGD 213 >UniRef50_A2UAS7 Cluster: Serine/threonine protein kinase; n=2; Bacillus|Rep: Serine/threonine protein kinase - Bacillus coagulans 36D1 Length = 698 Score = 83.0 bits (196), Expect = 4e-14 Identities = 60/202 (29%), Positives = 103/202 (50%), Gaps = 17/202 (8%) Query: 488 GKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----HAHVVRYYCTE 542 G G ++ R RDVAVK L P+ + RE+ + H ++V Y Sbjct: 19 GGGTANVYLARDMILDRDVAVKVLRPDFANEPEFIQRFHREAQSATSLVHPNIVSIYDVG 78 Query: 543 RDKQFRYIALELCSA-TLQDYVEKKLNFECKID-SVEILRQATMGLSHLHSMDIVHRDVK 600 + YI +E TL+ Y+++ N ++ +++I+ Q ++H H I+HRD+K Sbjct: 79 EEDDLNYIVMENVEGMTLKQYIQQ--NGPVSVEKTLDIMGQLAAAIAHAHDNHIIHRDIK 136 Query: 601 PHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTT 660 P N+L+ S G V+ I+DFG++ L+ S +R + V G+ +++PE G T Sbjct: 137 PQNILI---SHDGVVK--ITDFGIAMALS--ATSITRTNAVLGSVHYLSPEQARGGVATY 189 Query: 661 SIDIFSLGCVFYYVLSKGQHPF 682 DI++LG V + +L+ G+ PF Sbjct: 190 KSDIYALGIVMFELLT-GRLPF 210 >UniRef50_Q75I98 Cluster: Putative uncharacterized protein OSJNBa0004L11.12; n=3; Oryza sativa|Rep: Putative uncharacterized protein OSJNBa0004L11.12 - Oryza sativa subsp. japonica (Rice) Length = 654 Score = 83.0 bits (196), Expect = 4e-14 Identities = 60/222 (27%), Positives = 117/222 (52%), Gaps = 19/222 (8%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEI 578 ++E+ALL + + H ++V+YY T++++ YI +EL + +L +K + ++ + Sbjct: 429 EQEIALLSQFE-HENIVQYYGTDKEESKLYIFIELVTQGSLSSLYQKYKLRDSQVSAYT- 486 Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRR 638 RQ GL +LH ++VHRD+K N+L+ G V+ ++DFGL+K+++ +++ R Sbjct: 487 -RQILNGLVYLHERNVVHRDIKCANILV---HANGSVK--LADFGLAKEMS--KINMLR- 537 Query: 639 SGVTGTDGWIAPEMINGERT-TTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDY 697 G+ W+APE++N ++T DI+SLGC +L++ P+ +V A + G Sbjct: 538 -SCKGSVYWMAPEVVNPKKTYGPQADIWSLGCTVLEMLTR-NIPYPNVEWTNAFFMIGKG 595 Query: 698 NLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739 + L ++ + I + P RP ++ +P Sbjct: 596 ERPQIPSYLSKD----AQDFISQCVQVDPEQRPSASQLMSHP 633 >UniRef50_A7PH70 Cluster: Chromosome chr17 scaffold_16, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr17 scaffold_16, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 846 Score = 83.0 bits (196), Expect = 4e-14 Identities = 81/265 (30%), Positives = 129/265 (48%), Gaps = 26/265 (9%) Query: 487 LGKGCEGTFVYRGTFDKRD-VAVKRLLPECFTFADREVALLR----ESDAHAHVVRY--Y 539 +GKG G+ VY+ + VAVK+L P A+++ L + H ++VR + Sbjct: 584 IGKGGHGS-VYKAELPSGNIVAVKKLHPSDMDMANQKDFLNKVRAMTEIKHRNIVRLLGF 642 Query: 540 CTERDKQFR-YIALELCS-ATLQDYVE-KKLNFECKIDSVEILRQATMGLSHLHSMDIVH 596 C+ F Y LE S AT+ E KKL + ++ ++ + A + H S IVH Sbjct: 643 CSYPRHSFLVYEYLERGSLATILSREEAKKLGWATRVKIIKGVAHALSYMHHDCSPPIVH 702 Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656 RD+ +N+LL + A IS+ G +K L +V S +S + GT G++APE Sbjct: 703 RDISSNNILLD-----SQYEAHISNLGTAKLL---KVDSSNQSKLAGTVGYVAPEHAYTM 754 Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPFGDVL----RRQANILTGDYNLDHLDKILPEEELV 712 + T D++S G + V+ KG+HP +L + NI+ D L + P++E Sbjct: 755 KVTEKTDVYSFGVIALEVI-KGRHPGDQILSISVSPEKNIVLKDMLDPRLPPLTPQDEGE 813 Query: 713 VIKI--LIRAMISAKPSARPPCETI 735 V+ I L A ++A P +RP E I Sbjct: 814 VVAIIKLATACLNANPQSRPTMEII 838 >UniRef50_Q4QEC3 Cluster: Protein kinase, putative; n=4; Leishmania|Rep: Protein kinase, putative - Leishmania major Length = 702 Score = 83.0 bits (196), Expect = 4e-14 Identities = 67/210 (31%), Positives = 105/210 (50%), Gaps = 20/210 (9%) Query: 481 FQTDQVLGKG----CEGTFVYRGTFDKRDVAVKRL-LPECFTFADREVALLRESDAHAHV 535 FQ +VLG+G C GT+ + V L P+ E+++ R H HV Sbjct: 49 FQCGRVLGRGGFAKCYEVSDETGTYALKAVNRASLEKPKTLQKLHSEISIHRRMK-HKHV 107 Query: 536 VRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDI 594 V + T RD+ + Y+ LE C TL D ++ + F ++ ++ Q L ++HS + Sbjct: 108 VEFLRTFRDRYYVYMLLEKCDHGTLMDLLKVR-RFSVA-ETQYVMLQCLSALQYMHSECV 165 Query: 595 VHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMIN 654 +HRD+KP N++L E+ I DFGL+ +L + R+ + GT +IAPE+I+ Sbjct: 166 IHRDLKPGNIMLDR-----ELNVKIGDFGLAAEL---QYDGERKRTICGTPNYIAPEIID 217 Query: 655 GERTTTS--IDIFSLGCVFYYVLSKGQHPF 682 + S +D +SLG V Y L GQ PF Sbjct: 218 HKSHGHSYEVDTWSLG-VILYTLLVGQPPF 246 >UniRef50_A3FQ16 Cluster: Calmodulin-domain protein kinase 1, putative; n=3; Apicomplexa|Rep: Calmodulin-domain protein kinase 1, putative - Cryptosporidium parvum Iowa II Length = 538 Score = 83.0 bits (196), Expect = 4e-14 Identities = 72/227 (31%), Positives = 114/227 (50%), Gaps = 26/227 (11%) Query: 521 REVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEIL 579 REV LL++ D H ++++ + D YI EL + L D + K+ F + D+ I+ Sbjct: 122 REVELLKKLD-HPNIMKLFEILEDSSSFYIVGELYTGGELFDEIIKRKRFS-EHDAARII 179 Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639 +Q G++++H +IVHRD+KP N+LL +++ I DFGLS ++ Sbjct: 180 KQVFSGITYMHKHNIVHRDLKPENILLESKEKDCDIK--IIDFGLSTCFQ----QNTKMK 233 Query: 640 GVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-----GDVLRRQANILT 694 GT +IAPE++ G D++S G + Y +LS G PF D+L+R + T Sbjct: 234 DRIGTAYYIAPEVLRG-TYDEKCDVWSAGVILYILLS-GTPPFYGKNEYDILKR---VET 288 Query: 695 GDYNLDHLDKILPEEELVV--IKILIRAMISAKPSARPPCETILKYP 739 G Y D LP+ + K LIR M++ PS R L++P Sbjct: 289 GKYAFD-----LPQWRTISDDAKDLIRKMLTFHPSLRITATQCLEHP 330 >UniRef50_A0DMG4 Cluster: Chromosome undetermined scaffold_56, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_56, whole genome shotgun sequence - Paramecium tetraurelia Length = 517 Score = 83.0 bits (196), Expect = 4e-14 Identities = 77/277 (27%), Positives = 127/277 (45%), Gaps = 28/277 (10%) Query: 469 IGEGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRE 528 IG G +I ++ DQ G +G DK+ + +++ RE+ +L Sbjct: 36 IGRGNFATVQIGYKIDQE-NSGFKGKCYAIKCIDKQRIGFEQI--------QRELEILSR 86 Query: 529 SDAHAHVVRYYCTERDKQFRYIALELCSA--TLQDYVEKKLNFECKIDSVEILRQATMGL 586 D H +++R + D Y +E C LQ ++ E ++ + I+RQ + Sbjct: 87 LD-HPNIIRVFEEYEDLNHFYFVMEYCRGGELLQQIIKHGAQTE-RMTQI-IMRQLFSAV 143 Query: 587 SHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGV----- 641 +LH I+HRD+KP N++L+ G ++R I DFGLSK+ + + +RS Sbjct: 144 GYLHERGIIHRDLKPENLMLANADGDFDIR--IIDFGLSKREQVIKKPQQQRSKCRHQTK 201 Query: 642 TGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDH 701 GT ++APE++ G + T D +SLGC+ YVL G+ PF Q NL+ Sbjct: 202 VGTPIYVAPEVLKGVYSET-CDEWSLGCIM-YVLLFGEPPFSGQNIHQLEQQINKPNLNF 259 Query: 702 LDKILPEEELVVIKILIRAMISAKPSARPPCETILKY 738 I E + ++ K+L P+ R C LK+ Sbjct: 260 RLNISAECQDLITKLL-----EPNPNKRITCLQALKH 291 >UniRef50_A0CWJ1 Cluster: Chromosome undetermined scaffold_3, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_3, whole genome shotgun sequence - Paramecium tetraurelia Length = 379 Score = 83.0 bits (196), Expect = 4e-14 Identities = 73/266 (27%), Positives = 122/266 (45%), Gaps = 17/266 (6%) Query: 474 MKIGKITFQTDQVLGKGCEGTFVYRGTFD-KRDVAVKRLLPECFTFADREVALLRESDAH 532 +KI I + LG+G G F K+ VA+K + +++ + L + Sbjct: 7 LKINSIVYIIQAPLGQGTFGKVYKAQQFSSKKVVAIK--VQNQINESEKALLLQFKEKNF 64 Query: 533 AHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592 ++V Y E YI +E CS +L D ++ N D+ + +Q + GL LHS Sbjct: 65 KNLVNIYDYEEQHNHTYIVMEYCSHSLYDQIQT--NTINPKDTRYVFKQISNGLYELHSQ 122 Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAM--ISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650 + HRD+KP N+L+ G V+ M + DFG SK N R++ + GT ++AP Sbjct: 123 GLAHRDLKPANILICQLQDRGHVQEMYKLCDFGTSK--NSQRLT----TACVGTPYYLAP 176 Query: 651 EMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGD-VLRRQANILTGDYNLDHLDKILPEE 709 E + + S+DI++LG V Y + + G VL+ I + N +D + + Sbjct: 177 EQLQQQTYDKSVDIWALGAVMYELFTNTPLFSGSTVLQIYDKIKNYEINA-QIDNL--ND 233 Query: 710 ELVVIKILIRAMISAKPSARPPCETI 735 + K L+++M+ P R E I Sbjct: 234 LDIKYKNLLKSMLKKNPQERISIEEI 259 >UniRef50_A0CS09 Cluster: Chromosome undetermined scaffold_26, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_26, whole genome shotgun sequence - Paramecium tetraurelia Length = 595 Score = 83.0 bits (196), Expect = 4e-14 Identities = 59/206 (28%), Positives = 111/206 (53%), Gaps = 17/206 (8%) Query: 485 QVLGKGCEGTFVYR-GTFDKRDVAVK---RLLPECFTFADREVALLRESDAHAHVVRYYC 540 + LG G G V + K VAVK + + F ++E A+ + + H ++V++Y Sbjct: 69 ETLGHGAFGLVVKAFNNYSKVLVAVKIISKATIKKFEALEQEAAIFSQLN-HQNIVKFYD 127 Query: 541 TERDKQFRYIALELCSA-TLQDYVEKKLNFE--CKIDSVEILRQATMG-LSHLHSMDIVH 596 +R I +E+ + +LQ ++ KL + +++ ++ + Q +G LS++H VH Sbjct: 128 IKRTDTKILIEMEIINGGSLQKLMDTKLKYNQWFEVEEIKQIIQGILGALSYIHENHFVH 187 Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGE 656 RD+KP N+L+ + I+DFGLS N R + ++ GT ++APE++ + Sbjct: 188 RDLKPDNILIGEAANV----VKITDFGLSSHHN--RYALMQKK--CGTLTYMAPELLLKK 239 Query: 657 RTTTSIDIFSLGCVFYYVLSKGQHPF 682 ++D++S+G + Y +L+KGQHP+ Sbjct: 240 VYNKNVDVWSVGVIMYQLLNKGQHPY 265 >UniRef50_A0CRU6 Cluster: Chromosome undetermined scaffold_25, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_25, whole genome shotgun sequence - Paramecium tetraurelia Length = 503 Score = 83.0 bits (196), Expect = 4e-14 Identities = 58/221 (26%), Positives = 101/221 (45%), Gaps = 8/221 (3%) Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQ 581 E++++R+ + Y E + + L L Y+ + +I ++ Sbjct: 172 EISIMRKIQFQGIIRLYEVYETEHHIWLVTDYLEGGELFQYLRNQPQGFNEIQVALLMHN 231 Query: 582 ATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLN-IGRVSFSRRSG 640 L +LHS I+HRD+KP N++L P +V I+DFGL+ N G+ F R Sbjct: 232 LLNSLDYLHSQGIIHRDIKPENLILRSPLNASDV--YIADFGLADYYNPEGKYLFKR--- 286 Query: 641 VTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLD 700 GT G++APE++ + +D+FS G + + +LS GQ PF + + I + +D Sbjct: 287 -CGTPGYVAPEILQEKNYDYKVDVFSAGILMFIMLS-GQSPFQTKSKNELVIKNYNCEID 344 Query: 701 HLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF 741 + L ++ L+ M+S P R + L +P F Sbjct: 345 YTINNLQQKISPEALQLLMIMLSPNPQTRYTAKQALCHPWF 385 >UniRef50_O59790 Cluster: Serine/threonine-protein kinase ark1; n=21; Ascomycota|Rep: Serine/threonine-protein kinase ark1 - Schizosaccharomyces pombe (Fission yeast) Length = 355 Score = 83.0 bits (196), Expect = 4e-14 Identities = 75/267 (28%), Positives = 124/267 (46%), Gaps = 25/267 (9%) Query: 481 FQTDQVLGKGCEGTFVYRGTFDKRD--VAVKRLLPECFTFADREVALLRESDA-----HA 533 F+ + LGKG G VY K VA+K L + E + RE + H Sbjct: 89 FEIGKPLGKGKFGR-VYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHK 147 Query: 534 HVVRYYCTERDKQFRYIALELCS-ATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSM 592 +++R Y D++ Y+ LE L ++ + F ++ S I + A LS+LH Sbjct: 148 NILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMAN-ALSYLHKK 206 Query: 593 DIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEM 652 ++HRD+KP N+LL + GE++ +SDFG S +RR+ + GT ++ PEM Sbjct: 207 HVIHRDIKPENILLGI---DGEIK--LSDFGWSV-----HAPSNRRTTLCGTLDYLPPEM 256 Query: 653 INGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELV 712 + G+ T +D++SLG + Y L G PF D+ A + +D +P Sbjct: 257 VEGKEHTEKVDLWSLGVLTYEFL-VGAPPFEDMSGHSATY----KRIAKVDLKIPSFVPP 311 Query: 713 VIKILIRAMISAKPSARPPCETILKYP 739 + LI ++ P R E ++++P Sbjct: 312 DARDLISRLLQHNPEKRMSLEQVMRHP 338 >UniRef50_UPI0000D9C1EE Cluster: PREDICTED: similar to calcium/calmodulin-dependent protein kinase ID isoform 2; n=2; Eutheria|Rep: PREDICTED: similar to calcium/calmodulin-dependent protein kinase ID isoform 2 - Macaca mulatta Length = 622 Score = 82.6 bits (195), Expect = 5e-14 Identities = 68/213 (31%), Positives = 103/213 (48%), Gaps = 18/213 (8%) Query: 532 HAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLH 590 H ++V Y+ ++L S L D + +K F + D+ ++RQ + +LH Sbjct: 315 HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTLIRQVLDAVYYLH 373 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAP 650 M IVHRD+KP N+L S E + MISDFGLSK G V S GT G++AP Sbjct: 374 RMGIVHRDLKPENLLYY--SQDEESKIMISDFGLSKMEGKGDV----MSTACGTPGYVAP 427 Query: 651 EMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDV--LRRQANILTGDYNLD--HLDKIL 706 E++ + + ++D +S+G V Y+L G PF D + IL +Y D + D I Sbjct: 428 EVLAQKPYSKAVDCWSIG-VIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDIS 486 Query: 707 PEEELVVIKILIRAMISAKPSARPPCETILKYP 739 K IR ++ P+ R CE ++P Sbjct: 487 DS-----AKDFIRNLMEKDPNKRYTCEQAARHP 514 >UniRef50_Q4RVD3 Cluster: Chromosome 15 SCAF14992, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15 SCAF14992, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 702 Score = 82.6 bits (195), Expect = 5e-14 Identities = 55/157 (35%), Positives = 83/157 (52%), Gaps = 9/157 (5%) Query: 526 LRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMG 585 L + +H HVV++ D++ YI LELCS ++ K + + + LRQ G Sbjct: 129 LHRTLSHKHVVKFSHHFEDQENIYIFLELCSRKSLAHIWKARHTLTEPEVRYYLRQIISG 188 Query: 586 LSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTD 645 L +LHS I+HRD+K N ++ E+R + DFGL+ KL R+ + GT Sbjct: 189 LKYLHSRGILHRDLKLGNFFVNENM---ELR--LGDFGLAAKLETVE---QRKKTICGTP 240 Query: 646 GWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 ++APE++N + T D++SLGCV Y L G PF Sbjct: 241 NYLAPEVLNRQGHGTESDVWSLGCVM-YTLMCGNPPF 276 >UniRef50_Q6MBC4 Cluster: Putative serine/threonine protein kinase; n=2; Bacteria|Rep: Putative serine/threonine protein kinase - Protochlamydia amoebophila (strain UWE25) Length = 529 Score = 82.6 bits (195), Expect = 5e-14 Identities = 67/216 (31%), Positives = 112/216 (51%), Gaps = 20/216 (9%) Query: 475 KIGKITFQTDQVLGKGCEGTFVYRGTF-DKRD-VAVKRLLPECFTFADREVALLRESDA- 531 KIG +Q + +L KG + +Y T D +D + +K L PE + + LRES+ Sbjct: 27 KIGP--YQVEALLEKGGM-SILYLATHPDTKDPITIKVLFPEFVSNPEMVQRFLRESEII 83 Query: 532 ----HAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGL 586 H ++V+ Y + YIA+E +L+ Y+ + L K ++E++ + +M L Sbjct: 84 GLADHPNIVKLYGQGEWEGGLYIAMEFIQGISLRQYLLRNL-ISLK-HALELVMEISMAL 141 Query: 587 SHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDG 646 HLH+ ++HRDVKP N+L++ G + DFG+++ L G+ + + GT Sbjct: 142 CHLHAHGVIHRDVKPENILVTESGG-----VKVIDFGIAQLLTEGQTDPKSQRRLIGTPI 196 Query: 647 WIAPEMING-ERTTTSIDIFSLGCVFY-YVLSKGQH 680 +++PE N E T+ DI+SLG + Y VL K H Sbjct: 197 YMSPEQKNNPESTSYPSDIYSLGIITYELVLGKLSH 232 >UniRef50_A0W4X5 Cluster: Serine/threonine protein kinase with Chase2 sensor precursor; n=1; Geobacter lovleyi SZ|Rep: Serine/threonine protein kinase with Chase2 sensor precursor - Geobacter lovleyi SZ Length = 825 Score = 82.6 bits (195), Expect = 5e-14 Identities = 67/216 (31%), Positives = 109/216 (50%), Gaps = 23/216 (10%) Query: 481 FQTDQVLGKGCEGTFVYRGTFDK--RDVAVKRLLPECFT---FADREVALLRESDA---- 531 ++ + LG+G G VY G K R VA+K + E + + RE++A Sbjct: 559 YEIQKELGRGAMGV-VYLGKDPKINRLVAIKTVRFEEVDPDLLEETKKRFFREAEAAGTL 617 Query: 532 -HAHVVRYYCTERDKQFRYIALELCSAT-LQDYVEKKLNFECKIDSVEILRQATMGLSHL 589 H ++V Y ++ Y+A+EL + L Y++K+ K ++I+ GL+ Sbjct: 618 NHPNIVTIYDVGEEEDLAYVAMELLEGSDLTPYIKKEKLLPAKT-LLKIIGSVAEGLAFA 676 Query: 590 HSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIA 649 H IVHRD+KP N++L + GT I+DFG+++ I S ++ V GT +++ Sbjct: 677 HEKGIVHRDIKPANIML-LKDGT----VKIADFGIAR---ITTSSATQTGTVLGTPSYMS 728 Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF-GD 684 PE + G++ D+FSLG Y +L GQ PF GD Sbjct: 729 PEQVAGQKVDGRSDLFSLGVAMYELLC-GQKPFSGD 763 >UniRef50_Q9BMX6 Cluster: Phosphoinositide-dependent protein kinase I; n=2; Protostomia|Rep: Phosphoinositide-dependent protein kinase I - Aplysia californica (California sea hare) Length = 822 Score = 82.6 bits (195), Expect = 5e-14 Identities = 70/245 (28%), Positives = 120/245 (48%), Gaps = 21/245 (8%) Query: 485 QVLGKGCEGT-FVYRGTFDKRDVAVK-----RLLPECFT-FADREVALLRESDAHAHVVR 537 +V+G+G T ++ + +++ A+K L+ E T F RE +L + D H +R Sbjct: 376 KVIGEGSYSTVYLAKEVSTQKEFAIKVCDKKHLIRERKTHFVMREKEVLMKLD-HPFFIR 434 Query: 538 YYCTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVH 596 T +D + Y L + L Y+ K F+ + + L +LHS+ IVH Sbjct: 435 LAYTFQDPERLYYTLTYARNGELLGYLHKLSAFDVPCTRF-YTAEIVLALEYLHSLGIVH 493 Query: 597 RDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNI-GRVSFSRRSGVTGTDGWIAPEMING 655 RD+KP N+LLS ++ I+DFG SK L+ + R++ GT +++PE++N Sbjct: 494 RDLKPENILLS-----EDMHIKITDFGTSKILSSDSKPEVKRKNSFVGTAEYVSPEVLNN 548 Query: 656 ERTTTSIDIFSLGCVFYYVLSKGQHPF--GDVLRRQANILTGDYNLDHLDKILPEEELVV 713 + D++ LGC+ Y LS G PF G+ + I+ +Y D + P + +V Sbjct: 549 QPANFGSDLWGLGCIIYQCLS-GSLPFRCGNEYQTFQKIVKAEY--DFPEGFHPHAKDLV 605 Query: 714 IKILI 718 K+L+ Sbjct: 606 QKLLV 610 >UniRef50_Q8IL26 Cluster: Ser/Thr protein kinase, putative; n=1; Plasmodium falciparum 3D7|Rep: Ser/Thr protein kinase, putative - Plasmodium falciparum (isolate 3D7) Length = 1558 Score = 82.6 bits (195), Expect = 5e-14 Identities = 52/158 (32%), Positives = 87/158 (55%), Gaps = 18/158 (11%) Query: 546 QFRYIALELCSA-TLQDYVEKKLNFECKIDSV--EILRQATMGLSHLHSMDIVHRDVKPH 602 ++ YI +E C TL++ ++ F C+ + + E+++Q G+S++H M I+HRD+KP Sbjct: 607 KYLYILMEYCPGKTLREAID--CGFICRNEKLIWELIKQILKGISYIHDMKIMHRDIKPS 664 Query: 603 NVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSI 662 N+ L + + A I DFGL+ ++ +++ S GT +I+PE +NGE Sbjct: 665 NIFLQITDNI--LIAKIGDFGLTTRIGDTQINPS-----AGTIHYISPEQLNGEPFNEKA 717 Query: 663 DIFSLGCVFYYVLSKGQHPFGDVLRRQ---ANILTGDY 697 DIFSLG VF+ + PF + R +N+L G Y Sbjct: 718 DIFSLGVVFFEMF---HEPFSTSMERSITLSNLLKGIY 752 >UniRef50_Q4Q920 Cluster: Protein kinase, putative; n=3; Leishmania|Rep: Protein kinase, putative - Leishmania major Length = 1025 Score = 82.6 bits (195), Expect = 5e-14 Identities = 61/193 (31%), Positives = 99/193 (51%), Gaps = 22/193 (11%) Query: 485 QVLGKGCEGTFVYRGTFDKRD--VAVKRL-----LPECFTFADREVALLRESDAHAHVVR 537 ++LG+G G VY T D +AVK + + EV+++ + H ++V Sbjct: 747 KLLGRGSYGA-VYEATSDLTGGKMAVKMFYFSQNVESSISTLLNEVSIMCSLN-HPNIVH 804 Query: 538 YYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHR 597 Y+ ER + +ELC A+L D + + + V+I+RQ +++LHS I HR Sbjct: 805 YFHCERKDNNVSLFMELCEASLTDIIVGRRQKPAHLSVVQIIRQVLTAIAYLHSRGIAHR 864 Query: 598 DVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGER 657 DVKP N+LL GE ++DFG + + N G+ V GT ++APE+ G+ Sbjct: 865 DVKPQNILLK-----GET-VKLTDFGTAIQGNAGK-------EVRGTFRYMAPEVYKGDP 911 Query: 658 TTTSIDIFSLGCV 670 + S DI+S+GC+ Sbjct: 912 HSLSCDIWSIGCL 924 >UniRef50_A0DFL9 Cluster: Chromosome undetermined scaffold_49, whole genome shotgun sequence; n=10; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_49, whole genome shotgun sequence - Paramecium tetraurelia Length = 543 Score = 82.6 bits (195), Expect = 5e-14 Identities = 73/250 (29%), Positives = 123/250 (49%), Gaps = 27/250 (10%) Query: 522 EVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYV-EKKLNFECKIDSVEIL 579 E+ ++R+ + HAH+++ + Y+ALEL +L D + EK L +I +I+ Sbjct: 188 ELKIMRQLN-HAHIMQMHEVYETSNSLYVALELLEGGSLYDLIKEKTLLSTTQIQ--QIM 244 Query: 580 RQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRS 639 GL H+H I+HRD+K N+L V +I+DFGL+ K++ + R Sbjct: 245 VGVLQGLHHMHQKKIMHRDLKLENILFKQQKQMDSV--VIADFGLATKVDEPVYLYYR-- 300 Query: 640 GVTGTDGWIAPEMINGE----RTTTSIDIFSLGCVFYYVLSKGQ----HPFGDVLRRQAN 691 GT G++APE+IN + + DIFSLG VFY +LS Q +G V+++ Sbjct: 301 --CGTPGYVAPEVINIKDVQGHYSEVCDIFSLGLVFYLLLSGKQAFPGKSYGTVVKQNRE 358 Query: 692 ILTGDYNLDHLDKILPEEELVVIKILIRAMISAKPSARPPCETILKYPMF--WCKQSILN 749 + D+ + L + P + L L++ M+ P+ R LK+P Q + Sbjct: 359 AVI-DFKIKQLQQ-APSQAL----DLMKKMLERDPNKRVSATDCLKHPFLAEMNNQMADD 412 Query: 750 FLQDVSDQVE 759 F+ D D+++ Sbjct: 413 FVNDSFDEID 422 >UniRef50_Q756N1 Cluster: AER223Cp; n=1; Eremothecium gossypii|Rep: AER223Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 902 Score = 82.6 bits (195), Expect = 5e-14 Identities = 65/212 (30%), Positives = 112/212 (52%), Gaps = 22/212 (10%) Query: 485 QVLGKGCEGTFVYRGTFDKRD--VAVKRLLPECFTFADR---EVALLRESDAHAHVVRYY 539 QV+GKG G VY+ D +A+K + E E+ LL+ H ++V+Y+ Sbjct: 23 QVIGKGAYGV-VYKAVNRATDQVIAIKAIEYENEEELHEHMLEIDLLKNLK-HENIVKYH 80 Query: 540 CTERDKQFRYIALELC-SATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRD 598 + YI LE C +L+D ++K+ E K + +RQ GL +LH ++HRD Sbjct: 81 GFIQSSHELYILLEYCIRGSLRDLIKKEALSEAKAKTY--VRQTLRGLQYLHDQGVIHRD 138 Query: 599 VKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERT 658 +K N+LL + G V+ ++DFG+S ++N ++++ G+ W+APE++ G+ Sbjct: 139 IKAANLLL---TENGVVK--LADFGVSTRVNNMAMTYA------GSPNWMAPEVMLGKGA 187 Query: 659 TTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQA 690 +T DI+SLG +L+ G PF +++ A Sbjct: 188 STVSDIWSLGATVVELLT-GNPPFYNLVNEAA 218 >UniRef50_A4RDS9 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 1514 Score = 82.6 bits (195), Expect = 5e-14 Identities = 59/177 (33%), Positives = 95/177 (53%), Gaps = 12/177 (6%) Query: 509 KRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKL 567 K+ + E D+E+ ++ D H ++V+Y ER + I LE S ++ + K Sbjct: 1266 KKRMKELVAALDQEIETMQHLD-HVNIVQYLGCERKETSISIFLEYISGGSIGSCLRKNG 1324 Query: 568 NFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKK 627 FE + + RQ GL++LH I+HRD+K N+LL + GT A ISDFG+SKK Sbjct: 1325 KFEESVVQ-SLTRQTLSGLAYLHREGILHRDLKADNILLDV-DGT----AKISDFGISKK 1378 Query: 628 LNIGRVSFSRRSGVTGTDGWIAPEMI--NGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 + + + + G+ W+APE+I GE + +DI+SLGCV + + G+ P+ Sbjct: 1379 TD-NIYGNDKSNSMQGSVFWMAPEVIRSQGEGYSAKVDIWSLGCVVLEMFA-GRRPW 1433 >UniRef50_A3LT13 Cluster: Predicted protein; n=1; Pichia stipitis|Rep: Predicted protein - Pichia stipitis (Yeast) Length = 806 Score = 82.6 bits (195), Expect = 5e-14 Identities = 72/264 (27%), Positives = 128/264 (48%), Gaps = 21/264 (7%) Query: 481 FQTDQVLGKGCEGTFVYRG--TFDKRDVAVKRLLPEC----FTFADREVALLRESDAHAH 534 ++ +V+G+G G VY+G K+ VA+K L + + +E+ L E + Sbjct: 5 YKRTEVIGRGKFG-IVYKGYNKQTKQVVAIKVLNLDTEEDEVSDVQQEIKFLSELKNVPN 63 Query: 535 VVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDI 594 V +YY + + +I ++ C+ + K FE K V I+R+ + LS +H + + Sbjct: 64 VTQYYGSFLNDTKLWIIMDYCAGGSLRTILKSGVFEEKYIGV-IVRELLLALSAVHKLGV 122 Query: 595 VHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMI- 653 +HRD+K NVL+ T E ++ DFG++ K+ + +R+ + GT W+APE+I Sbjct: 123 IHRDLKAANVLI-----TKEGSVLLCDFGVAAKITSNAL---KRTTMAGTPYWMAPEVIR 174 Query: 654 NGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVV 713 G+ + DI+SLG + Y ++ G P+ D + AN + ++ E V Sbjct: 175 KGDTYNSKADIWSLG-ITIYEIATGNPPYCD---KDANWAMQMISKSTPPRLEGREYSVA 230 Query: 714 IKILIRAMISAKPSARPPCETILK 737 +K I + P RP + +LK Sbjct: 231 LKECIALCLDENPDERPSADDLLK 254 >UniRef50_A4IFZ4 Cluster: LOC565828 protein; n=2; Euteleostomi|Rep: LOC565828 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 500 Score = 82.2 bits (194), Expect = 6e-14 Identities = 52/169 (30%), Positives = 94/169 (55%), Gaps = 10/169 (5%) Query: 520 DREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEI 578 +REV+++++ H H++ + Y+ ELC L+D ++K +F + ++ I Sbjct: 93 EREVSIMKQVK-HEHIIHLEEVFETPKRMYLVTELCEGGDLKDLLQKNKHFT-EEETRHI 150 Query: 579 LRQATMGLSHLHSMDIVHRDVKPHNVLL-SMPSGTGE--VRAMISDFGLS-KKLNIGRVS 634 ++ + + +LH DIVHRD+K N+L+ S G V ++DFGLS +K +G S Sbjct: 151 IKSLSEAIVYLHKKDIVHRDLKLENILVKSCHQGNDNDMVNIKVTDFGLSVQKGGVG--S 208 Query: 635 FSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFG 683 + GT ++APE++NG + + D++S+G + Y +L G+ PFG Sbjct: 209 ENMLQATCGTPIYMAPEVVNGHQYSQQCDLWSIGVIMYMLLC-GEPPFG 256 >UniRef50_Q895P6 Cluster: Serine/threonine protein kinase; n=6; Clostridium|Rep: Serine/threonine protein kinase - Clostridium tetani Length = 619 Score = 82.2 bits (194), Expect = 6e-14 Identities = 69/222 (31%), Positives = 107/222 (48%), Gaps = 19/222 (8%) Query: 471 EGEMKIGKITFQTDQVLGKGCEGTF--VYRGT--FDKRDVAVKRLLPECFTFADREVALL 526 E + IG + ++L K EG VY+ F R VAVK L E A Sbjct: 13 ESVVMIGTLLGNRYELLEKVGEGGMAEVYKAKCHFLNRYVAVKILKEEFSQDAQFVEKFK 72 Query: 527 RESDAHA-----HVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILR 580 RE+ A A ++V Y ++ YI +E TL+D + KK K ++V++ Sbjct: 73 REATAAASISDNNIVNIYDVGSEENINYIVMEYVQGETLKDVIRKKGKIPYK-EAVKLAI 131 Query: 581 QATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSG 640 Q GL H +I+HRD+KPHN+L+ T + ++DFG++K N V+ + S Sbjct: 132 QIAKGLECAHRNNIIHRDIKPHNILV-----TADNLVKVTDFGIAKATN--SVTITNTSQ 184 Query: 641 VTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 + G+ + +PE G DI+SLG V Y +++ GQ P+ Sbjct: 185 IIGSVHYFSPEQAKGGFIDFRTDIYSLGIVLYEMVT-GQLPY 225 >UniRef50_Q4JYC1 Cluster: Serine/threonine protein kinase PknB; n=1; Corynebacterium jeikeium K411|Rep: Serine/threonine protein kinase PknB - Corynebacterium jeikeium (strain K411) Length = 722 Score = 82.2 bits (194), Expect = 6e-14 Identities = 59/189 (31%), Positives = 94/189 (49%), Gaps = 17/189 (8%) Query: 504 RDVAVKRLLPECF---TFADR--EVALLRESDAHAHVVRYYCT----ERDKQFRYIALE- 553 RDVAVK + P+ TF +R A H +V Y T + D YI +E Sbjct: 36 RDVAVKMMRPDLARDTTFLERFRREAQNAAKLNHPAIVAVYDTGQTPDEDGAVPYIVMER 95 Query: 554 LCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTG 613 + TL+D ++ D+ ++ Q L H I+HRD+KP NV+++ TG Sbjct: 96 VHGETLRDIIQDSGKMSLN-DAAAVMSQVCSALFFSHEAGIIHRDIKPANVMIT---NTG 151 Query: 614 EVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYY 673 V+ M DFG+++ L+ + ++ + V GT +++PE G+ DI++ GCVF Y Sbjct: 152 AVKVM--DFGIARALSDSSSAMTQTAAVIGTAQYLSPEQARGQSADARSDIYAAGCVF-Y 208 Query: 674 VLSKGQHPF 682 L+ G+ PF Sbjct: 209 ELATGKAPF 217 >UniRef50_P74451 Cluster: Serine/threonine protein kinase; n=1; Synechocystis sp. PCC 6803|Rep: Serine/threonine protein kinase - Synechocystis sp. (strain PCC 6803) Length = 631 Score = 82.2 bits (194), Expect = 6e-14 Identities = 51/153 (33%), Positives = 85/153 (55%), Gaps = 9/153 (5%) Query: 532 HAHVVRYYCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLH 590 H ++V + E RY+ ++ C TL+D ++ + C +++LRQ +GL+ H Sbjct: 82 HPNIVACHGLEYHPGGRYLVMDYCEGGTLRDIIDGDGDL-CLAGKIDLLRQILLGLAQAH 140 Query: 591 SMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSK-KLNIGRVSFSRRSGVTGTDGWIA 649 DIVH D+KP N+LL +P G + +SDFG+++ G +FS+ G TG+ ++A Sbjct: 141 QHDIVHCDLKPENILL-IPRAEG-WQVKVSDFGIARLTAKTGNPNFSK--GYTGSPAYMA 196 Query: 650 PEMINGERTTTSIDIFSLGCVFYYVLSKGQHPF 682 PE G+ + S DI+++G + Y L G PF Sbjct: 197 PERFYGKFSVAS-DIYAVG-ILLYELIVGDRPF 227 >UniRef50_A6CDL3 Cluster: Probable protein kinase yloP-putative serine/threonine protein kinase; n=1; Planctomyces maris DSM 8797|Rep: Probable protein kinase yloP-putative serine/threonine protein kinase - Planctomyces maris DSM 8797 Length = 943 Score = 82.2 bits (194), Expect = 6e-14 Identities = 72/251 (28%), Positives = 119/251 (47%), Gaps = 22/251 (8%) Query: 486 VLGKG-CEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDA-----HAHVVRYY 539 ++GKG ++ +R A+K L + A RE+ A H ++VR Y Sbjct: 81 LVGKGGMSSVYLAEHVLMRRRCAIKVLPSKRVNDASYLARFHREAQAVASLDHINIVRAY 140 Query: 540 CT----ERDKQFRYIALELCSAT-LQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDI 594 E D + ++ +E LQ+ V K + + D+V +RQ GL+H H D+ Sbjct: 141 DVDHEKENDAEIHFLVMEYVDGQDLQEIVTKTGPLDIR-DAVNYIRQGAKGLAHAHEADM 199 Query: 595 VHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGR---VSFSRRSGVTGTDGWIAPE 651 VHRDVKP N+L+ G V+ I D GL++ + G ++ + V GT ++APE Sbjct: 200 VHRDVKPGNLLV---DSKGVVK--ILDLGLARFFHEGEDKSLTIAHDEKVLGTADYLAPE 254 Query: 652 M-INGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQANILTGDYNLDHLDKILPEEE 710 I+ + + DI+SLGC Y++L+ G PF + Q + + N + P+ Sbjct: 255 QAIDSHQVDSRADIYSLGCTMYFLLT-GHPPFTEGSLAQRLMAHQNKNPPPVTDDRPDTP 313 Query: 711 LVVIKILIRAM 721 V++IL + M Sbjct: 314 PEVVQILEKMM 324 >UniRef50_A3DCY1 Cluster: Serine/threonine protein kinase; n=1; Clostridium thermocellum ATCC 27405|Rep: Serine/threonine protein kinase - Clostridium thermocellum (strain ATCC 27405 / DSM 1237) Length = 703 Score = 82.2 bits (194), Expect = 6e-14 Identities = 59/205 (28%), Positives = 100/205 (48%), Gaps = 15/205 (7%) Query: 484 DQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFT---FADREV--ALLRESDAHAHVVRY 538 +++ G G + R R VA+K L PE F R A S +H ++V Sbjct: 14 EKIGGGGMADVYKARCKLLNRFVAIKILKPEFINDEEFLKRFTIEAQAAASLSHPNIVSI 73 Query: 539 YCTERDKQFRYIALELCSA-TLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHR 597 Y ++ YI +E + TL++Y+++ K D+V I Q + H H +VHR Sbjct: 74 YDVGQENDIHYIVMEYVNGQTLKEYLDENGALYWK-DAVNIAIQICQAIEHAHKNHVVHR 132 Query: 598 DVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGER 657 D+KPHN+LL T + ++DFG+++ ++ ++ + G+ + +PE G Sbjct: 133 DIKPHNILL-----TKDGMLKVTDFGIARAVSSSTITMA--GNAIGSVHYFSPEQARGGF 185 Query: 658 TTTSIDIFSLGCVFYYVLSKGQHPF 682 T D++SLG V Y +L+ G+ PF Sbjct: 186 TDEKSDLYSLGIVLYELLT-GRVPF 209 >UniRef50_Q5EC56 Cluster: Phosphoenolpyruvate carboxylase kinase 4; n=21; Magnoliophyta|Rep: Phosphoenolpyruvate carboxylase kinase 4 - Zea mays (Maize) Length = 293 Score = 82.2 bits (194), Expect = 6e-14 Identities = 62/217 (28%), Positives = 99/217 (45%), Gaps = 10/217 (4%) Query: 528 ESDAHAHVVRYYCTERDKQFRYIALELCSAT-LQDYVEKKLNFEC-KIDSVEILRQATMG 585 E D + V++ + + ++LC+ L D++ + + D+ ++ Q Sbjct: 67 EGDGNPGVLQVRAVYEGDAWTHTVMDLCTGPDLLDWIRLRRGAPVPEPDAARVVAQLAEA 126 Query: 586 LSHLHSMDIVHRDVKPHNVLLSM-PSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGT 644 L+ H +VHRDVKP NVLL + P+G R ++DFG + L G + R G+ GT Sbjct: 127 LAGCHRRGVVHRDVKPDNVLLDVDPAGEAPPRVRLADFGSAAWLGEG--ARGRAEGLVGT 184 Query: 645 DGWIAPEMINGERTTTSIDIFSLGCVFYYVLSKGQHPFGDVLRRQ--ANILTGDYNLDHL 702 +APE++ G +D++S G V Y +LS G PFG A +L G Sbjct: 185 PHDVAPEVVAGGEYGEKVDVWSAGVVMYALLSGGALPFGGETAADVFAAVLRGSL---RF 241 Query: 703 DKILPEEELVVIKILIRAMISAKPSARPPCETILKYP 739 L K L+R M+ S R E +L++P Sbjct: 242 PPALFAGVSPAAKDLMRRMMCRDVSRRFSAEQVLRHP 278 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.321 0.137 0.419 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,090,531,700 Number of Sequences: 1657284 Number of extensions: 48041516 Number of successful extensions: 129985 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 2778 Number of HSP's successfully gapped in prelim test: 7384 Number of HSP's that attempted gapping in prelim test: 116614 Number of HSP's gapped (non-prelim): 12802 length of query: 973 length of database: 575,637,011 effective HSP length: 108 effective length of query: 865 effective length of database: 396,650,339 effective search space: 343102543235 effective search space used: 343102543235 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.8 bits) S2: 77 (35.1 bits)
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