Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000173-TA|BGIBMGA000173-PA|IPR003123|Vacuolar sorting
protein 9, IPR002110|Ankyrin
(896 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC050529-1|AAH50529.1| 1050|Homo sapiens ankyrin repeat domain 2... 223 2e-57
AK054561-1|BAB70755.1| 1060|Homo sapiens FLJ00040 protein protein. 223 2e-57
U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein. 125 8e-28
U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein. 125 8e-28
X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2... 122 4e-27
X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for ... 122 4e-27
U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein. 122 4e-27
M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein. 122 4e-27
AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4 var... 122 4e-27
Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein. 114 2e-24
X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein. 114 2e-24
BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein pr... 114 2e-24
AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 111 8e-24
AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 111 8e-24
AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 111 8e-24
AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 111 8e-24
AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 111 8e-24
AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens ... 106 3e-22
BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein. 105 9e-22
BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein. 105 9e-22
BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein. 105 9e-22
AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens ... 105 9e-22
AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein. 105 9e-22
BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein. 104 2e-21
AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein. 104 2e-21
AL834335-1|CAD39003.1| 407|Homo sapiens hypothetical protein pr... 99 6e-20
D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein. 97 3e-19
BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome, ma... 97 3e-19
BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome, ma... 97 3e-19
AL031177-5|CAA20117.1| 226|Homo sapiens proteasome (prosome, ma... 97 3e-19
AL031177-4|CAI43134.1| 193|Homo sapiens proteasome (prosome, ma... 97 3e-19
AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit ... 97 3e-19
X83703-1|CAA58676.1| 319|Homo sapiens nuclear protein protein. 96 4e-19
BC018667-1|AAH18667.1| 319|Homo sapiens ankyrin repeat domain 1... 96 4e-19
AY903446-1|AAX23581.1| 319|Homo sapiens liver ankyrin repeat do... 96 4e-19
AL590622-4|CAC70101.1| 319|Homo sapiens ankyrin repeat domain 1... 96 4e-19
BC112351-1|AAI12352.1| 725|Homo sapiens INVS protein protein. 95 7e-19
BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a pro... 95 7e-19
BC041665-1|AAH41665.1| 604|Homo sapiens Similar to inversin pro... 95 7e-19
AL445214-4|CAI39744.1| 1065|Homo sapiens inversin protein. 95 7e-19
AL445214-3|CAI39745.2| 895|Homo sapiens inversin protein. 95 7e-19
AL356798-2|CAI40807.1| 1065|Homo sapiens inversin protein. 95 7e-19
AL356798-1|CAI40808.2| 895|Homo sapiens inversin protein. 95 7e-19
AL137072-3|CAH72173.1| 1065|Homo sapiens inversin protein. 95 7e-19
AL137072-2|CAM16212.1| 895|Homo sapiens inversin protein. 95 7e-19
AF084382-2|AAC79457.1| 895|Homo sapiens inversin protein altern... 95 7e-19
AF084382-1|AAC79456.1| 1065|Homo sapiens inversin protein protein. 95 7e-19
AF084367-1|AAC79436.1| 1065|Homo sapiens inversin protein protein. 95 7e-19
BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein. 92 7e-18
AF039217-1|AAD02131.2| 1013|Homo sapiens inv candidate homolog p... 91 1e-17
BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein. 91 2e-17
BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein pr... 90 3e-17
AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens ... 90 3e-17
AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein. 90 3e-17
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 87 2e-16
BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein pr... 87 2e-16
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 87 2e-16
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 87 2e-16
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 87 2e-16
BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein. 87 2e-16
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 87 2e-16
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 87 2e-16
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 87 2e-16
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 87 3e-16
AF121775-1|AAF24125.1| 366|Homo sapiens nasopharyngeal carcinom... 87 3e-16
BC069013-1|AAH69013.1| 457|Homo sapiens ANKRD11 protein protein. 87 3e-16
AY533563-1|AAS45544.1| 2663|Homo sapiens ankyrin repeat-containi... 87 3e-16
AY373756-1|AAR25661.1| 2664|Homo sapiens ankyrin repeat-containi... 87 3e-16
AC017035-2|AAY15060.1| 394|Homo sapiens unknown protein. 87 3e-16
AB209186-1|BAD92423.1| 439|Homo sapiens ankyrin repeat domain 1... 87 3e-16
BC098394-1|AAH98394.1| 1327|Homo sapiens tankyrase, TRF1-interac... 86 5e-16
AB209339-1|BAD92576.1| 1055|Homo sapiens tankyrase, TRF1-interac... 86 5e-16
AK025859-1|BAB15260.1| 460|Homo sapiens protein ( Homo sapiens ... 86 6e-16
AF082557-1|AAC79842.1| 1094|Homo sapiens TRF1-interacting ankyri... 86 6e-16
AF082556-1|AAC79841.1| 1327|Homo sapiens TRF1-interacting ankyri... 86 6e-16
BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein. 85 8e-16
AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein. 85 8e-16
BC107759-1|AAI07760.1| 360|Homo sapiens ankyrin repeat domain 2... 84 2e-15
AL359388-4|CAI14194.1| 333|Homo sapiens ankyrin repeat domain 2... 84 2e-15
AL355315-9|CAI15463.1| 333|Homo sapiens ankyrin repeat domain 2... 84 2e-15
AJ583444-1|CAE47432.1| 449|Homo sapiens ankyrin repeat protein ... 84 2e-15
AJ304805-1|CAC19412.1| 333|Homo sapiens skeletal muscle ankyrin... 84 2e-15
AJ304804-1|CAC19411.1| 333|Homo sapiens skeletal muscle ankyrin... 84 2e-15
AB058599-1|BAB60958.1| 333|Homo sapiens ankyrin-repeat protein ... 84 2e-15
U40282-1|AAC16892.1| 452|Homo sapiens integrin-linked kinase pr... 83 3e-15
CR407673-1|CAG28601.1| 452|Homo sapiens ILK protein. 83 3e-15
BC062346-1|AAH62346.1| 361|Homo sapiens ankyrin repeat domain 1... 83 3e-15
BC001554-1|AAH01554.1| 452|Homo sapiens integrin-linked kinase ... 83 3e-15
AL137186-4|CAI41072.1| 361|Homo sapiens ankyrin repeat domain 1... 83 3e-15
AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens ... 83 3e-15
AJ404847-1|CAB99253.1| 452|Homo sapiens integrin-linked kinase ... 83 3e-15
AJ277481-1|CAB94832.1| 452|Homo sapiens integrin-linked kinase-... 83 3e-15
AF244139-1|AAF74449.1| 452|Homo sapiens integrin-linked kinase ... 83 3e-15
BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting se... 83 6e-15
BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting se... 83 6e-15
AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein. 83 6e-15
AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein. 83 6e-15
AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specifici... 83 6e-15
CR457336-1|CAG33617.1| 288|Homo sapiens ASB8 protein. 82 7e-15
BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein. 82 7e-15
BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein. 82 7e-15
BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein. 82 7e-15
BC001321-1|AAH01321.1| 288|Homo sapiens ankyrin repeat and SOCS... 82 7e-15
AY281131-1|AAP37612.1| 1249|Homo sapiens AIDA-1b protein. 82 7e-15
AK024908-1|BAB15033.1| 288|Homo sapiens NP3) mRNA. protein. 82 7e-15
BC043394-1|AAH43394.1| 751|Homo sapiens ANKRD17 protein protein. 81 2e-14
BC007747-1|AAH07747.2| 830|Homo sapiens ANKRD17 protein protein. 81 2e-14
AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6... 81 2e-14
AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6... 81 2e-14
AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1 var... 81 2e-14
BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 81 2e-14
BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 81 2e-14
BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6... 81 2e-14
AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein. 81 2e-14
AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein. 81 2e-14
AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein. 81 2e-14
DQ508934-1|ABF57994.1| 591|Homo sapiens SARP3 protein. 80 3e-14
DQ508815-1|ABF60230.1| 593|Homo sapiens SARP protein. 80 3e-14
BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH d... 80 3e-14
BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH d... 80 3e-14
BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH d... 80 3e-14
BC004457-1|AAH04457.2| 627|Homo sapiens ankyrin repeat and KH d... 80 3e-14
AK125596-1|BAC86214.1| 235|Homo sapiens protein ( Homo sapiens ... 80 3e-14
AK022041-1|BAB13958.1| 435|Homo sapiens protein ( Homo sapiens ... 80 3e-14
AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeat... 80 3e-14
AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeat... 80 3e-14
AF258557-1|AAG23760.1| 627|Homo sapiens PP2500 protein. 80 3e-14
AK095193-1|BAC04496.1| 389|Homo sapiens protein ( Homo sapiens ... 80 4e-14
BC107056-1|AAI07057.1| 305|Homo sapiens ankyrin repeat domain 2... 79 5e-14
AY196212-1|AAO40750.1| 305|Homo sapiens muscle ankyrin repeat p... 79 5e-14
AK092564-1|BAC03915.1| 263|Homo sapiens protein ( Homo sapiens ... 79 5e-14
AJ315766-1|CAC86120.1| 296|Homo sapiens Ankyrin repeat-containi... 79 5e-14
AF492401-1|AAO24067.1| 305|Homo sapiens diabetes related ankyri... 79 5e-14
AC092636-3|AAY14965.1| 305|Homo sapiens unknown protein. 79 5e-14
AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein pr... 79 7e-14
AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein. 79 7e-14
AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens ... 79 7e-14
AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein pr... 79 7e-14
BC101620-1|AAI01621.1| 1001|Homo sapiens ankyrin repeat domain 3... 79 9e-14
BC101618-1|AAI01619.1| 1001|Homo sapiens ankyrin repeat domain 3... 79 9e-14
AK091120-1|BAC03587.1| 1001|Homo sapiens protein ( Homo sapiens ... 79 9e-14
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 78 1e-13
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 78 1e-13
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 78 1e-13
AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens ... 78 1e-13
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 78 1e-13
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 78 1e-13
AB033076-1|BAA86564.2| 1777|Homo sapiens KIAA1250 protein protein. 78 1e-13
BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein. 78 2e-13
AL133620-1|CAB63746.1| 1031|Homo sapiens hypothetical protein pr... 78 2e-13
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 77 3e-13
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 77 3e-13
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 77 3e-13
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 77 3e-13
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 77 3e-13
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 77 3e-13
AL159174-2|CAI39610.1| 640|Homo sapiens ankyrin repeat domain 6... 77 3e-13
AL096678-3|CAI42281.1| 640|Homo sapiens ankyrin repeat domain 6... 77 3e-13
AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens ... 77 3e-13
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 77 3e-13
EF041819-1|ABL09300.1| 782|Homo sapiens several ankyrin repeat ... 77 4e-13
BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH d... 77 4e-13
AY057056-1|AAL25260.1| 151|Homo sapiens hepatocellular carcinom... 77 4e-13
AL117504-1|CAB55968.1| 641|Homo sapiens hypothetical protein pr... 77 4e-13
AL031177-6|CAI43131.1| 151|Homo sapiens proteasome (prosome, ma... 77 4e-13
BC057225-1|AAH57225.1| 330|Homo sapiens ANKRD12 protein protein. 76 6e-13
BC066643-1|AAH66643.1| 1202|Homo sapiens CASK interacting protei... 75 9e-13
AF451976-1|AAL49757.1| 1202|Homo sapiens cask-interacting protei... 75 9e-13
AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase, TRF1-interac... 75 1e-12
AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein. 75 1e-12
AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein. 75 1e-12
AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein. 75 1e-12
AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein. 75 1e-12
AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related prote... 75 1e-12
AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein ... 75 1e-12
U05681-1|AAC51348.1| 368|Homo sapiens B-cell leukemia/lymphoma ... 75 1e-12
M31732-1|AAA51815.1| 446|Homo sapiens BCL3 protein. 75 1e-12
BC064993-1|AAH64993.1| 446|Homo sapiens B-cell CLL/lymphoma 3 p... 75 1e-12
BC027033-1|AAH27033.1| 448|Homo sapiens hypothetical protein MG... 75 1e-12
AL691467-2|CAH73760.1| 410|Homo sapiens novel protein protein. 75 1e-12
AL691467-1|CAH73759.1| 448|Homo sapiens novel protein protein. 75 1e-12
AL592424-19|CAI16391.1| 410|Homo sapiens novel protein protein. 75 1e-12
AL592424-18|CAI16392.1| 448|Homo sapiens novel protein protein. 75 1e-12
AL590133-27|CAI13351.1| 448|Homo sapiens novel protein protein. 75 1e-12
AL590133-26|CAI13352.1| 410|Homo sapiens novel protein protein. 75 1e-12
AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS... 75 1e-12
AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens ... 75 1e-12
AB075861-1|BAB85567.1| 863|Homo sapiens KIAA1981 protein protein. 75 1e-12
BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein. 74 2e-12
BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS... 74 2e-12
BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS... 74 2e-12
AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS... 74 2e-12
AK001283-1|BAA91599.1| 445|Homo sapiens protein ( Homo sapiens ... 74 2e-12
AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens ... 74 2e-12
AF308285-1|AAG48253.1| 1188|Homo sapiens serologically defined b... 74 2e-12
AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein. 74 2e-12
AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein. 74 2e-12
AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS... 74 2e-12
BC070234-1|AAH70234.1| 371|Homo sapiens ANKRD12 protein protein. 74 3e-12
AY533564-1|AAS45545.2| 2039|Homo sapiens ankyrin repeat-containi... 74 3e-12
AY373757-1|AAR25662.1| 2062|Homo sapiens ankyrin repeat-containi... 74 3e-12
AK024808-1|BAB15014.1| 492|Homo sapiens protein ( Homo sapiens ... 74 3e-12
AF317425-1|AAG38609.1| 2062|Homo sapiens GAC-1 protein. 74 3e-12
DQ388145-2|ABD72216.1| 1482|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388144-2|ABD72214.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388143-2|ABD72212.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388142-2|ABD72210.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388141-2|ABD72208.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388140-2|ABD72206.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388139-2|ABD72204.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388138-2|ABD72202.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388137-2|ABD72200.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388136-2|ABD72198.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388135-2|ABD72196.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388134-2|ABD72194.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388133-2|ABD72192.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388132-2|ABD72190.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388131-2|ABD72188.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388130-2|ABD72186.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388129-2|ABD72184.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ388128-2|ABD72182.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ356264-2|ABC87066.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ356263-2|ABC87064.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ356262-2|ABC87062.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ356261-2|ABC87060.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ356260-2|ABC87058.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ356259-2|ABC87056.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ356258-2|ABC87054.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ356257-2|ABC87052.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ354391-2|ABC79055.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ354390-2|ABC79053.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ354389-2|ABC79051.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
DQ354388-2|ABC79049.1| 1663|Homo sapiens CTTNBP2 protein. 73 3e-12
BC106000-1|AAI06001.1| 1663|Homo sapiens cortactin binding prote... 73 3e-12
AK092230-1|BAC03833.1| 448|Homo sapiens ITOCHONDRIAL PRECURSOR.... 73 3e-12
AF377960-1|AAL32176.1| 1663|Homo sapiens cortactin-binding prote... 73 3e-12
AB051545-1|BAB21849.1| 1662|Homo sapiens KIAA1758 protein protein. 73 3e-12
AF451977-1|AAL49758.1| 1431|Homo sapiens cask-interacting protei... 73 5e-12
AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein p... 73 6e-12
D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein. 72 8e-12
BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and ster... 72 8e-12
BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for IM... 72 8e-12
AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and ster... 72 8e-12
AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and ster... 72 8e-12
AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and ster... 72 8e-12
AL031177-2|CAI43133.1| 185|Homo sapiens proteasome (prosome, ma... 72 8e-12
AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kina... 72 8e-12
AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein. 72 8e-12
AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 pro... 72 8e-12
X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein. 72 1e-11
BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lys... 72 1e-11
BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lys... 72 1e-11
BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein. 72 1e-11
BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein. 72 1e-11
BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein. 72 1e-11
BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein. 72 1e-11
BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein. 72 1e-11
AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated transc... 72 1e-11
AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated transc... 72 1e-11
AL671762-16|CAI18224.2| 1210|Homo sapiens euchromatic histone-ly... 72 1e-11
AL671762-15|CAI18226.2| 1176|Homo sapiens euchromatic histone-ly... 72 1e-11
AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic histone-ly... 72 1e-11
AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic histone-ly... 72 1e-11
AL662834-27|CAI17747.2| 1176|Homo sapiens euchromatic histone-ly... 72 1e-11
AL662834-26|CAI17748.1| 1210|Homo sapiens euchromatic histone-ly... 72 1e-11
AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic histone-ly... 72 1e-11
AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic histone-ly... 72 1e-11
AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein. 72 1e-11
AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein. 72 1e-11
BC063581-1|AAH63581.1| 274|Homo sapiens ankyrin repeat and SOCS... 71 1e-11
BC012917-1|AAH12917.1| 313|Homo sapiens ankyrin repeat, family ... 71 1e-11
AK222974-1|BAD96694.1| 274|Homo sapiens ankyrin repeat and SOCS... 71 1e-11
AK222958-1|BAD96678.1| 274|Homo sapiens ankyrin repeat and SOCS... 71 1e-11
AK026204-1|BAB15392.1| 274|Homo sapiens protein ( Homo sapiens ... 71 1e-11
AK022876-1|BAB14288.1| 313|Homo sapiens protein ( Homo sapiens ... 71 1e-11
AF451994-1|AAP97683.1| 318|Homo sapiens ankyrin repeat-containi... 71 1e-11
AF314032-1|AAK01621.1| 313|Homo sapiens ankyrin-repeat family A... 71 1e-11
AF251051-1|AAK34941.1| 313|Homo sapiens ankyrin protein. 71 1e-11
BC126428-1|AAI26429.1| 777|Homo sapiens BRCA1 associated RING d... 71 2e-11
BC118585-1|AAI18586.1| 273|Homo sapiens ASB16 protein protein. 71 2e-11
BC118584-1|AAI18585.1| 273|Homo sapiens ASB16 protein protein. 71 2e-11
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 71 2e-11
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 71 2e-11
BC075088-1|AAH75088.1| 453|Homo sapiens ankyrin repeat and SOCS... 71 2e-11
BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin... 71 2e-11
BC016881-1|AAH16881.1| 638|Homo sapiens Unknown (protein for IM... 71 2e-11
AK055435-1|BAB70922.1| 634|Homo sapiens protein ( Homo sapiens ... 71 2e-11
AK054727-1|BAB70800.1| 453|Homo sapiens protein ( Homo sapiens ... 71 2e-11
AF403034-1|AAL57353.1| 253|Homo sapiens ankyrin repeat domain-c... 71 2e-11
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 71 2e-11
U76638-1|AAB38316.1| 777|Homo sapiens BRCA1-associated RING dom... 71 2e-11
BC126426-1|AAI26427.1| 777|Homo sapiens BRCA1 associated RING d... 71 2e-11
BC030622-1|AAH30622.1| 301|Homo sapiens ankyrin repeat domain 2... 71 2e-11
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 71 2e-11
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 71 2e-11
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 71 2e-11
AK223409-1|BAD97129.1| 777|Homo sapiens BRCA1 associated RING d... 71 2e-11
AK057782-1|BAB71569.1| 268|Homo sapiens protein ( Homo sapiens ... 71 2e-11
AK027869-1|BAB55419.1| 773|Homo sapiens protein ( Homo sapiens ... 71 2e-11
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 71 2e-11
AF038042-1|AAB99978.1| 777|Homo sapiens BRCA1-associated RING d... 71 2e-11
AC016708-1|AAX93130.1| 777|Homo sapiens unknown protein. 71 2e-11
DQ309791-1|ABC48694.1| 871|Homo sapiens SamCystin protein. 70 3e-11
BC130610-1|AAI30611.1| 1672|Homo sapiens KIDINS220 protein protein. 70 3e-11
AL807776-3|CAM13062.1| 871|Homo sapiens ankyrin repeat and ster... 70 3e-11
AL353782-4|CAM14169.1| 871|Homo sapiens ankyrin repeat and ster... 70 3e-11
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 70 4e-11
BC028369-1|AAH28369.1| 617|Homo sapiens fem-1 homolog c (C. ele... 70 4e-11
AY249188-1|AAO64429.1| 617|Homo sapiens FEM1C protein. 70 4e-11
AL365415-1|CAB96957.1| 271|Homo sapiens similar to (NP_034322.1... 70 4e-11
AF391093-1|AAL37627.1| 617|Homo sapiens FEM1A protein. 70 4e-11
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 70 4e-11
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 70 4e-11
AB058688-1|BAB47414.1| 617|Homo sapiens KIAA1785 protein protein. 70 4e-11
AL442128-2|CAH73039.1| 420|Homo sapiens ankyrin repeat domain 1... 69 6e-11
AL157875-2|CAH70238.1| 420|Homo sapiens ankyrin repeat domain 1... 69 6e-11
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 69 6e-11
AF308292-1|AAG48260.1| 352|Homo sapiens serologically defined b... 69 6e-11
CR457302-1|CAG33583.1| 278|Homo sapiens ASB13 protein. 69 7e-11
BC012056-1|AAH12056.1| 173|Homo sapiens ASB13 protein protein. 69 7e-11
BC003542-1|AAH03542.2| 860|Homo sapiens M-phase phosphoprotein,... 69 7e-11
AL365356-2|CAH72614.1| 278|Homo sapiens ankyrin repeat and SOCS... 69 7e-11
AL359457-4|CAI16671.1| 860|Homo sapiens M-phase phosphoprotein,... 69 7e-11
AL354808-3|CAI41002.1| 860|Homo sapiens M-phase phosphoprotein,... 69 7e-11
Z97630-4|CAB63057.1| 300|Homo sapiens protein ( Human DNA seque... 69 1e-10
CR456471-1|CAG30357.1| 300|Homo sapiens dJ466N1.4 protein. 69 1e-10
BC066909-1|AAH66909.1| 300|Homo sapiens ankyrin repeat domain 5... 69 1e-10
BC014641-1|AAH14641.1| 300|Homo sapiens ankyrin repeat domain 5... 69 1e-10
BC004988-1|AAH04988.1| 669|Homo sapiens fem-1 homolog a (C. ele... 69 1e-10
AY356352-1|AAR10439.1| 669|Homo sapiens prostaglandin E recepto... 69 1e-10
AK000100-1|BAA90945.1| 420|Homo sapiens protein ( Homo sapiens ... 69 1e-10
AJ311359-1|CAC85342.1| 668|Homo sapiens putative sex determinin... 69 1e-10
AF403031-1|AAL57350.1| 286|Homo sapiens ankyrin repeat domain-c... 69 1e-10
U13048-1|AAA65710.1| 348|Homo sapiens nuclear respiratory facto... 68 1e-10
U13047-1|AAA65709.1| 360|Homo sapiens nuclear respiratory facto... 68 1e-10
U13046-1|AAA65708.1| 383|Homo sapiens nuclear respiratory facto... 68 1e-10
U13045-1|AAA65707.1| 395|Homo sapiens nuclear respiratory facto... 68 1e-10
D13317-1|BAA02574.1| 383|Homo sapiens transcription factor E4TF... 68 1e-10
D13316-1|BAA02573.1| 347|Homo sapiens transcription factor E4TF... 68 1e-10
BT006652-1|AAP35298.1| 360|Homo sapiens GA binding protein tran... 68 1e-10
BC050702-1|AAH50702.1| 395|Homo sapiens GA binding protein tran... 68 1e-10
BC036080-1|AAH36080.1| 383|Homo sapiens GA binding protein tran... 68 1e-10
BC016910-1|AAH16910.1| 360|Homo sapiens GA binding protein tran... 68 1e-10
AK123496-1|BAC85629.1| 656|Homo sapiens protein ( Homo sapiens ... 68 1e-10
AB075857-1|BAB85563.1| 606|Homo sapiens KIAA1977 protein protein. 68 1e-10
BC020817-1|AAH20817.2| 303|Homo sapiens ANKRD2 protein protein. 68 2e-10
AY557346-1|AAS67920.1| 273|Homo sapiens ankyrin repeat and SOCS... 68 2e-10
AL359388-5|CAI14193.1| 300|Homo sapiens ankyrin repeat domain 2... 68 2e-10
AL355315-10|CAI15462.1| 300|Homo sapiens ankyrin repeat domain ... 68 2e-10
CR545463-1|CAM28350.1| 545|Homo sapiens protein expressed in pr... 67 2e-10
BC127623-1|AAI27624.1| 458|Homo sapiens ACTBL1 protein protein. 67 2e-10
BC127123-1|AAI27124.1| 581|Homo sapiens protein expressed in pr... 67 2e-10
BC101006-1|AAI01007.1| 581|Homo sapiens protein expressed in pr... 67 2e-10
BC101005-1|AAI01006.1| 544|Homo sapiens POTE15 protein protein. 67 2e-10
BC066981-1|AAH66981.1| 381|Homo sapiens POTE15 protein protein. 67 2e-10
BC011608-1|AAH11608.2| 716|Homo sapiens EHMT1 protein protein. 67 2e-10
AY465173-1|AAS58872.1| 581|Homo sapiens POTE15A protein. 67 2e-10
AY465170-1|AAS58869.1| 544|Homo sapiens POTE15B protein. 67 2e-10
AY462874-1|AAS58868.1| 508|Homo sapiens POTE14A protein. 67 2e-10
AY083210-1|AAM09024.1| 1267|Homo sapiens euchromatic histone met... 67 2e-10
AL611925-3|CAH71077.1| 1267|Homo sapiens euchromatic histone-lys... 67 2e-10
AL590627-3|CAI17355.1| 1267|Homo sapiens euchromatic histone-lys... 67 2e-10
AK023196-1|BAB14456.1| 278|Homo sapiens ARPP-19) mRNA. protein. 67 2e-10
AB058779-1|BAB47505.2| 803|Homo sapiens KIAA1876 protein protein. 67 2e-10
AB028932-1|BAB56104.1| 917|Homo sapiens GLP1 protein. 67 2e-10
AL139008-2|CAM15100.1| 1011|Homo sapiens ankyrin repeat domain 1... 67 3e-10
BC126351-1|AAI26352.1| 467|Homo sapiens ASB10 protein protein. 66 4e-10
BC031303-1|AAH31303.1| 183|Homo sapiens ankyrin repeat domain 3... 66 4e-10
AY337578-1|AAQ17469.1| 233|Homo sapiens ankyrin repeat and SOCS... 66 4e-10
AK125565-1|BAC86204.1| 452|Homo sapiens protein ( Homo sapiens ... 66 4e-10
AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat... 66 4e-10
AF417920-1|AAL59159.1| 429|Homo sapiens ASB-10 protein. 66 4e-10
AC092636-4|AAY14966.1| 183|Homo sapiens unknown protein. 66 4e-10
AB209367-1|BAD92604.1| 192|Homo sapiens hypothetical protein MG... 66 4e-10
AB046856-1|BAB13462.2| 1864|Homo sapiens KIAA1636 protein protein. 66 4e-10
BC117367-1|AAI17368.1| 264|Homo sapiens ankyrin repeat domain 1... 66 5e-10
BC038951-1|AAH38951.1| 264|Homo sapiens ANKRD19 protein protein. 66 5e-10
BC028712-1|AAH28712.1| 264|Homo sapiens ANKRD19 protein protein. 66 5e-10
AL136981-3|CAC12726.1| 264|Homo sapiens ankyrin repeat domain 1... 66 5e-10
EF523384-1|ABP57734.1| 1075|Homo sapiens POTE-2 alpha-actin prot... 66 7e-10
AY465172-1|AAS58871.1| 486|Homo sapiens POTE14C protein. 66 7e-10
AY462873-1|AAS58867.1| 376|Homo sapiens POTE2C protein. 66 7e-10
AY462872-1|AAS58866.1| 394|Homo sapiens POTE2B protein. 66 7e-10
AY462871-1|AAS58865.1| 712|Homo sapiens POTE2A protein. 66 7e-10
AY462868-1|AAS58862.1| 376|Homo sapiens POTE2D protein. 66 7e-10
AY172978-1|AAO23914.1| 584|Homo sapiens POTE protein. 66 7e-10
BX537857-1|CAD97864.1| 306|Homo sapiens hypothetical protein pr... 65 9e-10
BX537853-1|CAD97861.1| 302|Homo sapiens hypothetical protein pr... 65 9e-10
BC103875-1|AAI03876.1| 323|Homo sapiens ankyrin repeat and SOCS... 65 9e-10
BC103874-1|AAI03875.1| 323|Homo sapiens ankyrin repeat and SOCS... 65 9e-10
BC069340-1|AAH69340.1| 323|Homo sapiens ankyrin repeat and SOCS... 65 9e-10
BC032354-1|AAH32354.1| 587|Homo sapiens ankyrin repeat and SOCS... 65 9e-10
AJ251238-1|CAC17765.1| 587|Homo sapiens hypothetical protein pr... 65 9e-10
AF425642-1|AAL60519.1| 323|Homo sapiens ankyrin repeat domain-c... 65 9e-10
AB056723-1|BAB64532.1| 587|Homo sapiens ankyrin repeat-conteini... 65 9e-10
BC114558-1|AAI14559.1| 238|Homo sapiens regulatory factor X-ass... 65 1e-09
AF105428-1|AAD17973.1| 237|Homo sapiens putative protein RFX-Bd... 65 1e-09
AB209433-1|BAD92670.1| 1031|Homo sapiens HLA-B associated transc... 65 1e-09
BC014558-1|AAH14558.1| 627|Homo sapiens fem-1 homolog b (C. ele... 64 2e-09
BC010122-1|AAH10122.1| 627|Homo sapiens fem-1 homolog b (C. ele... 64 2e-09
AK096295-1|BAC04752.1| 681|Homo sapiens protein ( Homo sapiens ... 64 2e-09
AF204883-1|AAF69303.1| 627|Homo sapiens FEM1 beta protein. 64 2e-09
AF178632-1|AAF05314.1| 627|Homo sapiens FEM-1-like death recept... 64 2e-09
AB095935-1|BAC23111.1| 996|Homo sapiens KIAA2015 protein protein. 64 2e-09
AB007856-1|BAA23692.2| 627|Homo sapiens KIAA0396 protein. 64 2e-09
CR542199-1|CAG46996.1| 260|Homo sapiens RFXANK protein. 64 2e-09
CR456981-1|CAG33262.1| 260|Homo sapiens RFXANK protein. 64 2e-09
CR456543-1|CAG30429.1| 806|Homo sapiens PLA2G6 protein. 64 2e-09
BC114563-1|AAI14564.1| 260|Homo sapiens regulatory factor X-ass... 64 2e-09
BC051904-1|AAH51904.1| 752|Homo sapiens phospholipase A2, group... 64 2e-09
BC036742-1|AAH36742.2| 806|Homo sapiens phospholipase A2, group... 64 2e-09
AY522921-1|AAR92478.1| 806|Homo sapiens phospholipase A2, group... 64 2e-09
AL022322-2|CAA18446.1| 806|Homo sapiens phospholipase A2, group... 64 2e-09
AF117692-1|AAD30424.1| 806|Homo sapiens calcium-independent pho... 64 2e-09
AF116267-1|AAF34728.1| 806|Homo sapiens calcium-independent pho... 64 2e-09
AF105427-1|AAD17972.1| 260|Homo sapiens transcription factor RF... 64 2e-09
AF102989-1|AAD41723.1| 806|Homo sapiens Ca2+-independent phosph... 64 2e-09
AF102988-1|AAD41722.1| 752|Homo sapiens Ca2+-independent phosph... 64 2e-09
AF094760-1|AAC69883.1| 260|Homo sapiens RFXANK protein. 64 2e-09
AF064594-1|AAC97486.1| 806|Homo sapiens calcium-independent pho... 64 2e-09
AC003110-1|AAB86654.1| 196|Homo sapiens F14150_1 protein. 64 2e-09
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 64 3e-09
BC131801-1|AAI31802.1| 567|Homo sapiens protein phosphatase 1, ... 64 3e-09
BC022878-1|AAH22878.1| 776|Homo sapiens ankyrin repeat domain 5... 64 3e-09
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 64 3e-09
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 64 3e-09
AL121889-2|CAM27345.1| 467|Homo sapiens protein phosphatase 1, ... 64 3e-09
AL121889-1|CAI19080.1| 567|Homo sapiens protein phosphatase 1, ... 64 3e-09
AL109754-1|CAB87618.2| 776|Homo sapiens ankyrin repeat domain 5... 64 3e-09
AL031657-2|CAM28212.1| 467|Homo sapiens protein phosphatase 1, ... 64 3e-09
AL031657-1|CAI20058.1| 567|Homo sapiens protein phosphatase 1, ... 64 3e-09
AK057011-1|BAB71342.1| 258|Homo sapiens protein ( Homo sapiens ... 64 3e-09
AF362910-1|AAK52796.1| 567|Homo sapiens CAAX box protein TIMAP ... 64 3e-09
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 64 3e-09
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 64 3e-09
AB177855-1|BAD66833.1| 467|Homo sapiens KIAA0823 splice variant... 64 3e-09
AB020630-1|BAA74846.2| 578|Homo sapiens KIAA0823 protein protein. 64 3e-09
BC037542-1|AAH37542.1| 999|Homo sapiens MIB2 protein protein. 63 4e-09
BC016490-1|AAH16490.1| 1030|Homo sapiens MIB2 protein protein. 63 4e-09
AY462869-1|AAS58863.1| 498|Homo sapiens POTE8A protein. 63 4e-09
AL691432-4|CAM12833.1| 919|Homo sapiens mindbomb homolog 2 (Dro... 63 4e-09
AL691432-3|CAM12832.1| 753|Homo sapiens mindbomb homolog 2 (Dro... 63 4e-09
AL691432-2|CAM12831.1| 999|Homo sapiens mindbomb homolog 2 (Dro... 63 4e-09
AL691432-1|CAM12830.1| 948|Homo sapiens mindbomb homolog 2 (Dro... 63 4e-09
AK098785-1|BAC05413.1| 802|Homo sapiens protein ( Homo sapiens ... 63 4e-09
AK097106-1|BAC04952.1| 819|Homo sapiens protein ( Homo sapiens ... 63 4e-09
AK095914-1|BAC04646.1| 681|Homo sapiens protein ( Homo sapiens ... 63 4e-09
AK091610-1|BAC03707.1| 645|Homo sapiens protein ( Homo sapiens ... 63 4e-09
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 63 4e-09
AB097000-1|BAC77353.1| 999|Homo sapiens putative NFkB activatin... 63 4e-09
AB076693-1|BAC00994.1| 1009|Homo sapiens skeletrophin gamma prot... 63 4e-09
AB076692-1|BAC00993.1| 948|Homo sapiens skeletrophin beta protein. 63 4e-09
AB076691-1|BAC00992.1| 999|Homo sapiens skeletrophin alpha prot... 63 4e-09
AB074480-1|BAB92950.1| 1013|Homo sapiens skeletrophin protein. 63 4e-09
AB032965-1|BAA86453.1| 1124|Homo sapiens KIAA1139 protein protein. 63 4e-09
BC056266-1|AAH56266.1| 357|Homo sapiens ANKRD18A protein protein. 63 5e-09
BC017798-1|AAH17798.1| 239|Homo sapiens ankyrin repeat domain 4... 63 5e-09
AL591543-1|CAI17285.1| 992|Homo sapiens ankyrin repeat domain 1... 63 5e-09
AL390918-2|CAI15822.1| 940|Homo sapiens protein ( Human DNA seq... 63 5e-09
AL390918-1|CAI15821.1| 1858|Homo sapiens protein ( Human DNA seq... 63 5e-09
AL353143-2|CAH73222.1| 940|Homo sapiens protein ( Human DNA seq... 63 5e-09
AL353143-1|CAH73221.1| 1858|Homo sapiens protein ( Human DNA seq... 63 5e-09
AL161431-1|CAI15548.1| 1858|Homo sapiens protein ( Human DNA seq... 63 5e-09
AL157771-2|CAI16367.1| 940|Homo sapiens protein ( Human DNA seq... 63 5e-09
AL157771-1|CAI16366.1| 1858|Homo sapiens protein ( Human DNA seq... 63 5e-09
AL136132-2|CAH70520.1| 940|Homo sapiens protein ( Human DNA seq... 63 5e-09
AL136132-1|CAH70519.1| 1858|Homo sapiens protein ( Human DNA seq... 63 5e-09
AK127806-1|BAC87143.1| 935|Homo sapiens protein ( Homo sapiens ... 63 5e-09
AK025322-1|BAB15111.1| 416|Homo sapiens protein ( Homo sapiens ... 63 5e-09
AF025354-1|AAK60412.1| 239|Homo sapiens fetal globin-inducing f... 63 5e-09
AB020672-1|BAA74888.2| 1900|Homo sapiens KIAA0865 protein protein. 63 5e-09
BC117678-1|AAI17679.1| 581|Homo sapiens ANKHD1 protein protein. 62 6e-09
BC039715-1|AAH39715.1| 161|Homo sapiens ANKRD10 protein protein. 62 6e-09
BC001727-1|AAH01727.1| 220|Homo sapiens ANKRD10 protein protein. 62 6e-09
AL442128-1|CAH73037.1| 220|Homo sapiens ankyrin repeat domain 1... 62 6e-09
AL137614-1|CAB70843.1| 160|Homo sapiens hypothetical protein pr... 62 6e-09
AK021564-1|BAB13844.1| 140|Homo sapiens protein ( Homo sapiens ... 62 6e-09
AK000196-1|BAA91003.1| 239|Homo sapiens protein ( Homo sapiens ... 62 6e-09
BC101007-1|AAI01008.1| 301|Homo sapiens POTE15 protein protein. 62 8e-09
BC035234-1|AAH35234.1| 343|Homo sapiens ankyrin repeat domain 5... 62 8e-09
BC024189-1|AAH24189.2| 345|Homo sapiens fibronectin type III an... 62 8e-09
AY358154-1|AAQ88521.1| 371|Homo sapiens CG3104 hlg protein. 62 8e-09
AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin... 62 8e-09
AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin... 62 8e-09
AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin... 62 8e-09
AK093479-1|BAC04181.1| 530|Homo sapiens protein ( Homo sapiens ... 62 8e-09
DQ152234-1|AAZ77790.1| 707|Homo sapiens Shank2E protein. 62 1e-08
BC113481-1|AAI13482.1| 349|Homo sapiens ankyrin repeat and SOCS... 62 1e-08
BC113479-1|AAI13480.1| 349|Homo sapiens ankyrin repeat and SOCS... 62 1e-08
BC025024-1|AAH25024.1| 318|Homo sapiens Unknown (protein for IM... 62 1e-08
AK098736-1|BAC05399.1| 181|Homo sapiens protein ( Homo sapiens ... 62 1e-08
AK075298-1|BAC11532.1| 129|Homo sapiens protein ( Homo sapiens ... 62 1e-08
AK000904-1|BAA91417.1| 519|Homo sapiens protein ( Homo sapiens ... 62 1e-08
AF156779-1|AAD41896.1| 426|Homo sapiens ASB-4 protein protein. 62 1e-08
AC003079-1|AAB83943.2| 426|Homo sapiens unknown protein. 62 1e-08
BT006845-1|AAP35491.1| 528|Homo sapiens protein phosphatase 1, ... 61 1e-08
BC053506-1|AAH53506.1| 528|Homo sapiens protein phosphatase 1, ... 61 1e-08
BC049841-1|AAH49841.1| 528|Homo sapiens protein phosphatase 1, ... 61 1e-08
BC007854-1|AAH07854.1| 528|Homo sapiens protein phosphatase 1, ... 61 1e-08
AB033081-1|BAA86569.2| 1232|Homo sapiens KIAA1255 protein protein. 61 1e-08
>BC050529-1|AAH50529.1| 1050|Homo sapiens ankyrin repeat domain 27
(VPS9 domain) protein.
Length = 1050
Score = 223 bits (546), Expect = 2e-57
Identities = 137/416 (32%), Positives = 227/416 (54%), Gaps = 21/416 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T SRD G T LHVA++ G+A++++ L+ G+ +NATD + + LH A +G+Q+V L+
Sbjct: 455 TPFSRDDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLL 514
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LLH A+ ++ + NTPLHLA GH CVKA++Y+ S R ++ NE G+TPLH+
Sbjct: 515 LLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCR---LDIGNEKGDTPLHI 571
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
A++WGY+G+ L+++G+ +QN +T A N +IL V+++ + FE SSE
Sbjct: 572 AARWGYQGVIETLLQNGASTEIQNRLKETPLKCALNSKILSVMEAYHLS-FER-RQKSSE 629
Query: 664 VKKISCESEKPTSLKLQNLTLKCSDTNDASK---TIENLKLIERILRAISYGDVKLACFY 720
+ S+ ++ T S + +S+ T ++ + +E++LRA++ GD+++ +
Sbjct: 630 A-PVQSPQRSVDSISQESSTSSFSSMSASSRQEETKKDYREVEKLLRAVADGDLEMVRYL 688
Query: 721 MNIDYSAFIAPDKEKSNS-----LCHPLCECQYC----KRKTE-SCTDFDVNVCDSNGFT 770
++++ D E + S CHPLC+C C KR + + VNV +G +
Sbjct: 689 --LEWTEEDLEDAEDTVSAADPEFCHPLCQCPKCAPAQKRLAKVPASGLGVNVTSQDGSS 746
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
LH AA +G + +L+ + AN RN PLHLA V++ LLD+ A N
Sbjct: 747 PLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKK 806
Query: 831 DVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
D++ NTPL A G+ +LL + I N TAL A + H+ +++L+
Sbjct: 807 DLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELL 862
Score = 190 bits (462), Expect = 2e-47
Identities = 130/409 (31%), Positives = 215/409 (52%), Gaps = 39/409 (9%)
Query: 5 YDEIVSENPFFLELKNEYANLFQHCLSESWIICVPRIGSLTSRVFTVEDFCAHLLVPSDE 64
YDE + +NPF+L L+ +L I+ VP GSL+S + + F +++L+P +E
Sbjct: 4 YDEDLLKNPFYLALQKCRPDLCSKVAQIHGIVLVPCKGSLSSSIQSTCQFESYILIPVEE 63
Query: 65 LPETHFNTLTEKQVTVLNKVITVEVSKGLPLQSHILFEETFYTEDFMKYKVWCIESPLEP 124
HF TL K V + I + L ILFEETFY E + + CI PLE
Sbjct: 64 ----HFQTLNGKDVFIQGNRIKLGAGFACLLSVPILFEETFYNEKEESFSILCIAHPLEK 119
Query: 125 TKTTDDAVVSKK--YLSGINDCIDLLWTQAAAIG----------------PLR---DTVS 163
+++++ + L I D + L + LR D+ +
Sbjct: 120 RESSEEPLAPSDPFSLKTIEDVREFLGRHSERFDRNIASFHRTFRECERKSLRHHIDSAN 179
Query: 164 ELYTQCLQVTLQNRRLRDKSKSCKQVLENIKLSVESYMQHLLFDSIFKSICTSCAYEDAH 223
LYT+CLQ L++ L+ +K Q + +K +VE Y+ H +++ IFK + T A EDA
Sbjct: 180 ALYTKCLQQLLRDSHLKMLAKQEAQ-MNLMKQAVEIYVHHEIYNLIFKYVGTMEASEDAA 238
Query: 224 LNKKIRNMCDIQLRDLDIKKDLYHTVPKAKQILSKIDTYNTVLEKLVCLKQALNSINKKD 283
NK R++ D+Q +D+ +K + +P+AK+ L++++ + +KLVCL++ + I +
Sbjct: 239 FNKITRSLQDLQQKDIGVKPEFSFNIPRAKRELAQLNKCTSPQQKLVCLRKVVQLITQSP 298
Query: 284 SSN-NVVLLTADDLLPVFVFLVIKSGLPNWFSQLTYMKEFRFSSAGKCDGDESAFLITTL 342
S N+ + ADDLL V ++L++K+ +PNW + L+Y+K FRFSS K DE + +T+
Sbjct: 299 SQRVNLETMCADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSLAK---DELGYCLTSF 355
Query: 343 EAVIGHIQSGALTG-PPDPEAYYYYESNLTEENLSCKQRKSSLTESIST 390
EA I +I+ G+L+ PP+ E + + L KQR S L++ S+
Sbjct: 356 EAAIEYIRQGSLSAKPPESEGF--------GDRLFLKQRMSLLSQMTSS 396
Score = 99.1 bits (236), Expect = 6e-20
Identities = 65/202 (32%), Positives = 105/202 (51%), Gaps = 14/202 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+TS+D G + LHVA++HG+A ++ LL+ G+ A + ++ LH A +GH V+ L
Sbjct: 739 VTSQD--GSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCL 796
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L S A N+K++ NTPL A + GH V ++ +H +IN +N GNT LH A
Sbjct: 797 LDSNAKPNKKDLSGNTPLIYACSGGHHELVALLL---QHGA---SINASNNKGNTALHEA 850
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHN----LRILQVLKSCTPNLFEYIHIT 660
+ + LL+ HG+ + N +TA D A + +LQV+ SC +L +
Sbjct: 851 VIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDDVAETD 910
Query: 661 SSEVKKISCESEKPTSLKLQNL 682
E ++ + K + KL +L
Sbjct: 911 RKEY--VTVKIRKKWNSKLYDL 930
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/131 (34%), Positives = 59/131 (45%), Gaps = 6/131 (4%)
Query: 732 DKEKSNSLCHPLCECQYCKRKTESCTDFDVNVC-----DSNGFTALHYAARYGLDEFCNI 786
DK+ +CHPLC C C++ + D +V D G T LH AA G ++
Sbjct: 423 DKDTVQKMCHPLCFCDDCEKLVSGRLN-DPSVVTPFSRDDRGHTPLHVAAVCGQASLIDL 481
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
L+ A VN + TPLHLA V LLL A+ D NTPLH A G+
Sbjct: 482 LVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGH 541
Query: 847 IGAAKILLSYN 857
K L+ Y+
Sbjct: 542 EDCVKALVYYD 552
Score = 54.4 bits (125), Expect = 2e-06
Identities = 31/104 (29%), Positives = 54/104 (51%)
Query: 772 LHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID 831
LH A + G + L+ + A N ++ TPL A ++ LLL +GA+INA +
Sbjct: 781 LHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASN 840
Query: 832 VARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
NT LH+A ++ ++LL + + +LN ++TA+ A+
Sbjct: 841 NKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAE 884
Score = 50.0 bits (114), Expect = 4e-05
Identities = 28/86 (32%), Positives = 43/86 (50%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N D +G T L YA G E +L+ + A++N N K T LH A I V+ LLL
Sbjct: 804 NKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELLL 863
Query: 822 DNGANINAIDVARNTPLHDASETGNI 847
+GA++ ++ + T + A + I
Sbjct: 864 LHGASVQVLNKRQRTAVDCAEQNSKI 889
>AK054561-1|BAB70755.1| 1060|Homo sapiens FLJ00040 protein protein.
Length = 1060
Score = 223 bits (546), Expect = 2e-57
Identities = 137/416 (32%), Positives = 227/416 (54%), Gaps = 21/416 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T SRD G T LHVA++ G+A++++ L+ G+ +NATD + + LH A +G+Q+V L+
Sbjct: 465 TPFSRDDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLL 524
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LLH A+ ++ + NTPLHLA GH CVKA++Y+ S R ++ NE G+TPLH+
Sbjct: 525 LLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCR---LDIGNEKGDTPLHI 581
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
A++WGY+G+ L+++G+ +QN +T A N +IL V+++ + FE SSE
Sbjct: 582 AARWGYQGVIETLLQNGASTEIQNRLKETPLKCALNSKILSVMEAYHLS-FER-RQKSSE 639
Query: 664 VKKISCESEKPTSLKLQNLTLKCSDTNDASK---TIENLKLIERILRAISYGDVKLACFY 720
+ S+ ++ T S + +S+ T ++ + +E++LRA++ GD+++ +
Sbjct: 640 A-PVQSPQRSVDSISQESSTSSFSSMSASSRQEETKKDYREVEKLLRAVADGDLEMVRYL 698
Query: 721 MNIDYSAFIAPDKEKSNS-----LCHPLCECQYC----KRKTE-SCTDFDVNVCDSNGFT 770
++++ D E + S CHPLC+C C KR + + VNV +G +
Sbjct: 699 --LEWTEEDLEDAEDTVSAADPEFCHPLCQCPKCAPAQKRLAKVPASGLGVNVTSQDGSS 756
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
LH AA +G + +L+ + AN RN PLHLA V++ LLD+ A N
Sbjct: 757 PLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKK 816
Query: 831 DVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
D++ NTPL A G+ +LL + I N TAL A + H+ +++L+
Sbjct: 817 DLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELL 872
Score = 190 bits (462), Expect = 2e-47
Identities = 130/409 (31%), Positives = 215/409 (52%), Gaps = 39/409 (9%)
Query: 5 YDEIVSENPFFLELKNEYANLFQHCLSESWIICVPRIGSLTSRVFTVEDFCAHLLVPSDE 64
YDE + +NPF+L L+ +L I+ VP GSL+S + + F +++L+P +E
Sbjct: 14 YDEDLLKNPFYLALQKCRPDLCSKVAQIHGIVLVPCKGSLSSSIQSTCQFESYILIPVEE 73
Query: 65 LPETHFNTLTEKQVTVLNKVITVEVSKGLPLQSHILFEETFYTEDFMKYKVWCIESPLEP 124
HF TL K V + I + L ILFEETFY E + + CI PLE
Sbjct: 74 ----HFQTLNGKDVFIQGNRIKLGAGFACLLSVPILFEETFYNEKEESFSILCIAHPLEK 129
Query: 125 TKTTDDAVVSKK--YLSGINDCIDLLWTQAAAIG----------------PLR---DTVS 163
+++++ + L I D + L + LR D+ +
Sbjct: 130 RESSEEPLAPSDPFSLKTIEDVREFLGRHSERFDRNIASFHRTFRECERKSLRHHIDSAN 189
Query: 164 ELYTQCLQVTLQNRRLRDKSKSCKQVLENIKLSVESYMQHLLFDSIFKSICTSCAYEDAH 223
LYT+CLQ L++ L+ +K Q + +K +VE Y+ H +++ IFK + T A EDA
Sbjct: 190 ALYTKCLQQLLRDSHLKMLAKQEAQ-MNLMKQAVEIYVHHEIYNLIFKYVGTMEASEDAA 248
Query: 224 LNKKIRNMCDIQLRDLDIKKDLYHTVPKAKQILSKIDTYNTVLEKLVCLKQALNSINKKD 283
NK R++ D+Q +D+ +K + +P+AK+ L++++ + +KLVCL++ + I +
Sbjct: 249 FNKITRSLQDLQQKDIGVKPEFSFNIPRAKRELAQLNKCTSPQQKLVCLRKVVQLITQSP 308
Query: 284 SSN-NVVLLTADDLLPVFVFLVIKSGLPNWFSQLTYMKEFRFSSAGKCDGDESAFLITTL 342
S N+ + ADDLL V ++L++K+ +PNW + L+Y+K FRFSS K DE + +T+
Sbjct: 309 SQRVNLETMCADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSLAK---DELGYCLTSF 365
Query: 343 EAVIGHIQSGALTG-PPDPEAYYYYESNLTEENLSCKQRKSSLTESIST 390
EA I +I+ G+L+ PP+ E + + L KQR S L++ S+
Sbjct: 366 EAAIEYIRQGSLSAKPPESEGF--------GDRLFLKQRMSLLSQMTSS 406
Score = 99.1 bits (236), Expect = 6e-20
Identities = 65/202 (32%), Positives = 105/202 (51%), Gaps = 14/202 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+TS+D G + LHVA++HG+A ++ LL+ G+ A + ++ LH A +GH V+ L
Sbjct: 749 VTSQD--GSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCL 806
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L S A N+K++ NTPL A + GH V ++ +H +IN +N GNT LH A
Sbjct: 807 LDSNAKPNKKDLSGNTPLIYACSGGHHELVALLL---QHGA---SINASNNKGNTALHEA 860
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHN----LRILQVLKSCTPNLFEYIHIT 660
+ + LL+ HG+ + N +TA D A + +LQV+ SC +L +
Sbjct: 861 VIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDDVAETD 920
Query: 661 SSEVKKISCESEKPTSLKLQNL 682
E ++ + K + KL +L
Sbjct: 921 RKEY--VTVKIRKKWNSKLYDL 940
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/131 (34%), Positives = 59/131 (45%), Gaps = 6/131 (4%)
Query: 732 DKEKSNSLCHPLCECQYCKRKTESCTDFDVNVC-----DSNGFTALHYAARYGLDEFCNI 786
DK+ +CHPLC C C++ + D +V D G T LH AA G ++
Sbjct: 433 DKDTVQKMCHPLCFCDDCEKLVSGRLN-DPSVVTPFSRDDRGHTPLHVAAVCGQASLIDL 491
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
L+ A VN + TPLHLA V LLL A+ D NTPLH A G+
Sbjct: 492 LVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGH 551
Query: 847 IGAAKILLSYN 857
K L+ Y+
Sbjct: 552 EDCVKALVYYD 562
Score = 54.4 bits (125), Expect = 2e-06
Identities = 31/104 (29%), Positives = 54/104 (51%)
Query: 772 LHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID 831
LH A + G + L+ + A N ++ TPL A ++ LLL +GA+INA +
Sbjct: 791 LHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASN 850
Query: 832 VARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
NT LH+A ++ ++LL + + +LN ++TA+ A+
Sbjct: 851 NKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAE 894
Score = 50.0 bits (114), Expect = 4e-05
Identities = 28/86 (32%), Positives = 43/86 (50%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N D +G T L YA G E +L+ + A++N N K T LH A I V+ LLL
Sbjct: 814 NKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELLL 873
Query: 822 DNGANINAIDVARNTPLHDASETGNI 847
+GA++ ++ + T + A + I
Sbjct: 874 LHGASVQVLNKRQRTAVDCAEQNSKI 899
>U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein.
Length = 1088
Score = 125 bits (301), Expect = 8e-28
Identities = 106/405 (26%), Positives = 184/405 (45%), Gaps = 19/405 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A + ++E LL+ G+ I A + + +H A+ GH N++ L+H GA+
Sbjct: 20 NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 79
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N N+ T LH+A +G V+ ++ G ++ ++ TPLH++++ G
Sbjct: 80 PNTTNVRGETALHMAARSGQAEVVRYLV----QDGAQVEAKAKDD--QTPLHISARLGKA 133
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEY---IHITSSEVKKI 667
I + L++ G+ P N+ + + H L + + L ++ + IT+ +
Sbjct: 134 DIVQQLLQQGASP---NAATTSGYTPLH-LSAREGHEDVAAFLLDHGASLSITTKKGFTP 189
Query: 668 SCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA 727
+ K L++ NL L+ S + DA+ + + A Y + K+A ++ S
Sbjct: 190 LHVAAKYGKLEVANLLLQKSASPDAA----GKSGLTPLHVAAHYDNQKVALLLLDQGASP 245
Query: 728 FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNIL 787
A K L + Q T D N G ++H AA+ G + ++L
Sbjct: 246 HAAA-KNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 304
Query: 788 IFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
+ ANVN NK TPLHLAA ++ V +L++ GA+++A TPLH GNI
Sbjct: 305 LGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNI 364
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYAN 891
LL ++ + T L A + H II+ L+ N A+
Sbjct: 365 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNAS 409
Score = 90.6 bits (215), Expect = 2e-17
Identities = 83/354 (23%), Positives = 155/354 (43%), Gaps = 20/354 (5%)
Query: 539 NVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGN 598
N+ LL AN N K ++ TPLH+A + ++ ++ +H +I ESG
Sbjct: 2 NLRCDLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLL---KHGA---SIQAVTESGL 55
Query: 599 TPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH 658
TP+H+A+ G+ I L+ HG+ P+ N +TA A +V++ + +
Sbjct: 56 TPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEA 115
Query: 659 ITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKT-IENLKLIERILRAISYGDVKLA 717
+ + + + +Q L + + N A+ + L L R G +A
Sbjct: 116 KAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAR------EGHEDVA 169
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESC---TDFDVNVCDSNGFTALHY 774
F +D+ A ++ +K + H +Y K + + + +G T LH
Sbjct: 170 AFL--LDHGASLSITTKKGFTPLH--VAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 225
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AA Y + +L+ A+ + K TPLH+AA N+ + LL+ GA+ NA+
Sbjct: 226 AAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQG 285
Query: 835 NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDN 888
+H A++ G++ +LL N ++ L N + T L +A + + + +++ N
Sbjct: 286 IASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVN 339
Score = 87.8 bits (208), Expect = 1e-16
Identities = 86/385 (22%), Positives = 160/385 (41%), Gaps = 18/385 (4%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
LL+ + NA LN + LH A + V+ +LL GA+I TP+H+A GH
Sbjct: 7 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 66
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH 630
++ V ++ H G + N N G T LH+A++ G + R L++ G++ +
Sbjct: 67 VNIVSQLM----HHG--ASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDD 120
Query: 631 KTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTN 690
+T + L +++ T+S + + + +++ D +
Sbjct: 121 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGH----EDVAAFLLD-H 175
Query: 691 DASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCK 750
AS +I K + A YG +++A N+ +PD + L Y
Sbjct: 176 GASLSITTKKGFTPLHVAAKYGKLEVA----NLLLQKSASPDAAGKSGLTPLHVAAHYDN 231
Query: 751 RKTESC---TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHL 807
+K + NG+T LH AA+ + L+ A+ N ++ +HL
Sbjct: 232 QKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHL 291
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA ++ LLL AN+N + + TPLH A++ + A++L++ +
Sbjct: 292 AAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMG 351
Query: 868 KTALAVAKDKVHLTIIDLIDNYANK 892
T L V ++ I++ + ++ K
Sbjct: 352 YTPLHVGCHYGNIKIVNFLLQHSAK 376
Score = 83.4 bits (197), Expect = 3e-15
Identities = 76/318 (23%), Positives = 136/318 (42%), Gaps = 18/318 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+++ GKA IV+ LL+ G+ NA + + LH ++ GH++V LL GA+++
Sbjct: 122 TPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSI 181
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
TPLH+A G L ++ + + + A +SG TPLH+A+ + + +A
Sbjct: 182 TTKKGFTPLHVAAKYGKLEVANLLLQ------KSASPDAAGKSGLTPLHVAAHYDNQKVA 235
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEK 673
LL++ G+ P T A + + + + +T + + +++
Sbjct: 236 LLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQE 295
Query: 674 PTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDK 733
+ + +L L +A+ + N + + A V +A +N A +
Sbjct: 296 -GHVDMVSLLL----GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVN--QGAHVDAQT 348
Query: 734 EKSNSLCHPLCECQYCKRKTESCT---DFDVNVCDSNGFTALHYAARYGLDEFCNILIFN 790
+ + H C Y K + VN NG+T LH AA+ G N+L+ N
Sbjct: 349 KMGYTPLH--VGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQN 406
Query: 791 RANVNCRNKKAQTPLHLA 808
A+ N T L +A
Sbjct: 407 NASPNELTVNGNTALGIA 424
Score = 77.0 bits (181), Expect = 3e-13
Identities = 47/168 (27%), Positives = 84/168 (50%), Gaps = 13/168 (7%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + I TLLE G++ NA +++H A+ GH +++ +LL AN
Sbjct: 251 NGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNAN 310
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N N TPLHLA ++ + ++ H ++ + G TPLH+ +G
Sbjct: 311 VNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAH------VDAQTKMGYTPLHVGCHYGNI 364
Query: 611 GIARLLIEHGSE--PSLQNSY---HKTAFD-YAHNLRILQVLKSCTPN 652
I L++H ++ +N Y H+ A + H + +L + + +PN
Sbjct: 365 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL-LQNNASPN 411
Score = 70.5 bits (165), Expect = 2e-11
Identities = 36/127 (28%), Positives = 63/127 (49%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ + +G T LH AA+ +L+ A+V+ + K TPLH+ ++
Sbjct: 310 NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNF 369
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL + A +NA TPLH A++ G+ +LL N L TAL +A+ +
Sbjct: 370 LLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGY 429
Query: 880 LTIIDLI 886
++++D +
Sbjct: 430 ISVVDTL 436
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/93 (31%), Positives = 51/93 (54%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHV +G IV LL+ +++NA N + LH A+ +GH +++ +LL + A+
Sbjct: 351 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASP 410
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHS 584
N+ ++ NT L +A G++ V + E +
Sbjct: 411 NELTVNGNTALGIARRLGYISVVDTLKIVTEET 443
Score = 56.0 bits (129), Expect = 6e-07
Identities = 39/127 (30%), Positives = 61/127 (48%), Gaps = 3/127 (2%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T LH +AR G + L+ A+ N TPLHL+A V LLD+GA+++
Sbjct: 122 TPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSI 181
Query: 830 IDVARNTPLHDASETGNIGAAKILL--SYNPDITLLNATEKTALAVAKDKVHLTIIDLID 887
TPLH A++ G + A +LL S +PD + +A D + ++ L+D
Sbjct: 182 TTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALL-LLD 240
Query: 888 NYANKYA 894
A+ +A
Sbjct: 241 QGASPHA 247
>U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein.
Length = 4377
Score = 125 bits (301), Expect = 8e-28
Identities = 106/405 (26%), Positives = 184/405 (45%), Gaps = 19/405 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A + ++E LL+ G+ I A + + +H A+ GH N++ L+H GA+
Sbjct: 399 NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 458
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N N+ T LH+A +G V+ ++ G ++ ++ TPLH++++ G
Sbjct: 459 PNTTNVRGETALHMAARSGQAEVVRYLV----QDGAQVEAKAKDD--QTPLHISARLGKA 512
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEY---IHITSSEVKKI 667
I + L++ G+ P N+ + + H L + + L ++ + IT+ +
Sbjct: 513 DIVQQLLQQGASP---NAATTSGYTPLH-LSAREGHEDVAAFLLDHGASLSITTKKGFTP 568
Query: 668 SCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA 727
+ K L++ NL L+ S + DA+ + + A Y + K+A ++ S
Sbjct: 569 LHVAAKYGKLEVANLLLQKSASPDAA----GKSGLTPLHVAAHYDNQKVALLLLDQGASP 624
Query: 728 FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNIL 787
A K L + Q T D N G ++H AA+ G + ++L
Sbjct: 625 HAAA-KNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683
Query: 788 IFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
+ ANVN NK TPLHLAA ++ V +L++ GA+++A TPLH GNI
Sbjct: 684 LGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNI 743
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYAN 891
LL ++ + T L A + H II+ L+ N A+
Sbjct: 744 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNAS 788
Score = 115 bits (277), Expect = 7e-25
Identities = 98/406 (24%), Positives = 182/406 (44%), Gaps = 20/406 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
S+ +GL+ LH+A+ V+ LL+ ++ + +ALH A+ GH V +LL
Sbjct: 329 SKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLD 388
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
AN N K ++ TPLH+A + ++ ++ +H +I ESG TP+H+A+
Sbjct: 389 KKANPNAKALNGFTPLHIACKKNRIKVMELLL---KHGA---SIQAVTESGLTPIHVAAF 442
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
G+ I L+ HG+ P+ N +TA A +V++ + + +
Sbjct: 443 MGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTP 502
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKT-IENLKLIERILRAISYGDVKLACFYMNIDY 725
+ + + +Q L + + N A+ + L L R G +A F +D+
Sbjct: 503 LHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAR------EGHEDVAAFL--LDH 554
Query: 726 SAFIAPDKEKSNSLCHPLCECQYCKRKTESC---TDFDVNVCDSNGFTALHYAARYGLDE 782
A ++ +K + H +Y K + + + +G T LH AA Y +
Sbjct: 555 GASLSITTKKGFTPLH--VAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQK 612
Query: 783 FCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDAS 842
+L+ A+ + K TPLH+AA N+ + LL+ GA+ NA+ +H A+
Sbjct: 613 VALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAA 672
Query: 843 ETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDN 888
+ G++ +LL N ++ L N + T L +A + + + +++ N
Sbjct: 673 QEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVN 718
Score = 109 bits (262), Expect = 4e-23
Identities = 107/411 (26%), Positives = 177/411 (43%), Gaps = 27/411 (6%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ +G + LL + ++ T N+ + LH AS RG+ N++ +LL GA I
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ K D TPLH +GH V+ ++ R I ++G +PLH+A++ +
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLL------DRAAPILSKTKNGLSPLHMATQGDHLN 348
Query: 612 IARLLIEHG-SEPSLQNSYHKTAFDYAH--NLRILQVL--KSCTPNLFEYIHITSSEVKK 666
+LL++H + N Y AH + ++ +VL K PN T
Sbjct: 349 CVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLH--- 405
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYS 726
I+C K +K+ L LK + AS + I A G V + M+ S
Sbjct: 406 IAC---KKNRIKVMELLLK----HGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 458
Query: 727 AFIAPDK-EKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCN 785
+ E + + + + + + + D T LH +AR G +
Sbjct: 459 PNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQ 516
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
L+ A+ N TPLHL+A V LLD+GA+++ TPLH A++ G
Sbjct: 517 QLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYG 576
Query: 846 NIGAAKILL--SYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKYA 894
+ A +LL S +PD + +A D + ++ L+D A+ +A
Sbjct: 577 KLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALL-LLDQGASPHA 626
Score = 101 bits (242), Expect = 1e-20
Identities = 94/403 (23%), Positives = 171/403 (42%), Gaps = 18/403 (4%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
LTALHVA+ G + + LL+ + NA LN + LH A + V+ +LL GA+I
Sbjct: 368 LTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQ 427
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
TP+H+A GH++ V ++ H G + N N G T LH+A++ G +
Sbjct: 428 AVTESGLTPIHVAAFMGHVNIVSQLM----HHGA--SPNTTNVRGETALHMAARSGQAEV 481
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESE 672
R L++ G++ + +T + L +++ T+S + +
Sbjct: 482 VRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAR 541
Query: 673 KPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPD 732
+ +++ D + AS +I K + A YG +++A N+ +PD
Sbjct: 542 EGH----EDVAAFLLD-HGASLSITTKKGFTPLHVAAKYGKLEVA----NLLLQKSASPD 592
Query: 733 KEKSNSLCHPLCECQYCKRKTESCT---DFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
+ L Y +K + NG+T LH AA+ + L+
Sbjct: 593 AAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLE 652
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
A+ N ++ +HLAA ++ LLL AN+N + + TPLH A++ +
Sbjct: 653 YGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNV 712
Query: 850 AKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANK 892
A++L++ + T L V ++ I++ + ++ K
Sbjct: 713 AEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAK 755
Score = 97.5 bits (232), Expect = 2e-19
Identities = 94/384 (24%), Positives = 167/384 (43%), Gaps = 34/384 (8%)
Query: 512 LEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHL 571
++ G +IN + N +ALH AS GH V+ LL AN++ NT LH+A G
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 120
Query: 572 HCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHK 631
VK ++ N+N +++G TPL++A++ + + + L+++G+ SL
Sbjct: 121 EVVKVLV------TNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGF 174
Query: 632 T----AFDYAHNLRILQVLKSCTPNLFEY--IHITSSEVKKISCESEKPTSLKLQNLTLK 685
T A H+ + +L++ T +HI + + + K +L LQ
Sbjct: 175 TPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARK------DDTKAAALLLQ----- 223
Query: 686 CSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA-FIAPDKEKSNSLCHPLC 744
ND + +E+ + A YG++ +A +N + F A + +
Sbjct: 224 ----NDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 279
Query: 745 ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTP 804
K + D D G T LH AR G ++ +L+ A + + K +P
Sbjct: 280 NANMVKLLLDRGAKIDAKTRD--GLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSP 337
Query: 805 LHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL--SYNPDITL 862
LH+A + ++LLL + ++ + T LH A+ G+ AK+LL NP+
Sbjct: 338 LHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKA 397
Query: 863 LNATEKTALAVAKDKVHLTIIDLI 886
LN T L +A K + +++L+
Sbjct: 398 LNGF--TPLHIACKKNRIKVMELL 419
Score = 83.4 bits (197), Expect = 3e-15
Identities = 76/318 (23%), Positives = 136/318 (42%), Gaps = 18/318 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+++ GKA IV+ LL+ G+ NA + + LH ++ GH++V LL GA+++
Sbjct: 501 TPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSI 560
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
TPLH+A G L ++ + + + A +SG TPLH+A+ + + +A
Sbjct: 561 TTKKGFTPLHVAAKYGKLEVANLLLQ------KSASPDAAGKSGLTPLHVAAHYDNQKVA 614
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEK 673
LL++ G+ P T A + + + + +T + + +++
Sbjct: 615 LLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQE 674
Query: 674 PTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDK 733
+ + +L L +A+ + N + + A V +A +N A +
Sbjct: 675 -GHVDMVSLLL----GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVN--QGAHVDAQT 727
Query: 734 EKSNSLCHPLCECQYCKRKTESCT---DFDVNVCDSNGFTALHYAARYGLDEFCNILIFN 790
+ + H C Y K + VN NG+T LH AA+ G N+L+ N
Sbjct: 728 KMGYTPLH--VGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQN 785
Query: 791 RANVNCRNKKAQTPLHLA 808
A+ N T L +A
Sbjct: 786 NASPNELTVNGNTALGIA 803
Score = 77.0 bits (181), Expect = 3e-13
Identities = 45/134 (33%), Positives = 76/134 (56%), Gaps = 6/134 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ +GL ALH+AS G +V LL+ + ++A +ALH AS G V+ +L+ +G
Sbjct: 71 NQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNG 130
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN+N ++ + TPL++A HL VK F +G ++ A E G TPL +A + G
Sbjct: 131 ANVNAQSQNGFTPLYMAAQENHLEVVK----FLLDNGASQSL--ATEDGFTPLAVALQQG 184
Query: 609 YEGIARLLIEHGSE 622
++ + LL+E+ ++
Sbjct: 185 HDQVVSLLLENDTK 198
Score = 77.0 bits (181), Expect = 3e-13
Identities = 47/168 (27%), Positives = 84/168 (50%), Gaps = 13/168 (7%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + I TLLE G++ NA +++H A+ GH +++ +LL AN
Sbjct: 630 NGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNAN 689
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N N TPLHLA ++ + ++ H ++ + G TPLH+ +G
Sbjct: 690 VNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAH------VDAQTKMGYTPLHVGCHYGNI 743
Query: 611 GIARLLIEHGSE--PSLQNSY---HKTAFD-YAHNLRILQVLKSCTPN 652
I L++H ++ +N Y H+ A + H + +L + + +PN
Sbjct: 744 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL-LQNNASPN 790
Score = 70.5 bits (165), Expect = 2e-11
Identities = 36/127 (28%), Positives = 63/127 (49%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ + +G T LH AA+ +L+ A+V+ + K TPLH+ ++
Sbjct: 689 NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNF 748
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL + A +NA TPLH A++ G+ +LL N L TAL +A+ +
Sbjct: 749 LLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGY 808
Query: 880 LTIIDLI 886
++++D +
Sbjct: 809 ISVVDTL 815
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/93 (31%), Positives = 51/93 (54%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHV +G IV LL+ +++NA N + LH A+ +GH +++ +LL + A+
Sbjct: 730 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASP 789
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHS 584
N+ ++ NT L +A G++ V + E +
Sbjct: 790 NELTVNGNTALGIARRLGYISVVDTLKIVTEET 822
Score = 55.6 bits (128), Expect = 7e-07
Identities = 34/129 (26%), Positives = 62/129 (48%), Gaps = 6/129 (4%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
L ALH+A+ LL+ + + + + LH A+ G+ NV +LL+ A ++
Sbjct: 203 LPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVD 262
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ TPLH+A G+ + VK ++ R I+ G TPLH ++ G+E +
Sbjct: 263 FTARNDITPLHVASKRGNANMVKLLL------DRGAKIDAKTRDGLTPLHCGARSGHEQV 316
Query: 613 ARLLIEHGS 621
+L++ +
Sbjct: 317 VEMLLDRAA 325
Score = 53.6 bits (123), Expect = 3e-06
Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 1/119 (0%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AAR G E I N ++N N+ LHLA+ V+ LL AN++A
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 835 NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANK 892
NT LH AS G K+L++ ++ + T L +A + HL ++ L+DN A++
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQ 166
Score = 43.2 bits (97), Expect = 0.004
Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 4/131 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN NGFT L+ AA+ E L+ N A+ + + TPL +A V+ L
Sbjct: 132 NVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSL 191
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+N R LH A+ + AA +LL + + + + + T L +A +
Sbjct: 192 LLENDTK----GKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGN 247
Query: 880 LTIIDLIDNYA 890
+ + L+ N A
Sbjct: 248 INVATLLLNRA 258
>X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2)
protein.
Length = 1719
Score = 122 bits (295), Expect = 4e-27
Identities = 100/365 (27%), Positives = 166/365 (45%), Gaps = 14/365 (3%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G+T LH+AS G +V LL+ G++I +E + LH A+ GH + +LL GA
Sbjct: 238 NGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAP 297
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
I K + +P+H+A HL CV+ ++ + I+ TPLH+A+ G+
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQY------DAEIDDITLDHLTPLHVAAHCGHH 351
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCE 670
+A++L++ G++P+ + T A ++V++ +T S + +
Sbjct: 352 RVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVA 411
Query: 671 SEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIA 730
S ++NL + AS + N+K+ + A G ++A + + + + A
Sbjct: 412 SFMGHLPIVKNLLQR-----GASPNVSNVKVETPLHMAARAGHTEVAKYLLQ-NKAKVNA 465
Query: 731 PDKEKSNSLCHPLCECQYCKR-KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
K+ L H + K + + N+ + G T LH AAR G E L+
Sbjct: 466 KAKDDQTPL-HCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLE 524
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
A+ C KK TPLH+AA K V LLL+ A+ NA TPLH A N+
Sbjct: 525 KEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDI 584
Query: 850 AKILL 854
K+LL
Sbjct: 585 VKLLL 589
Score = 117 bits (281), Expect = 2e-25
Identities = 104/403 (25%), Positives = 180/403 (44%), Gaps = 18/403 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
++ +GL+ +H+A+ V LL+ +EI+ L+ + LH A+ GH V +LL
Sbjct: 300 AKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLD 359
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA N + ++ TPLH+A H+ ++ ++ +G +I+ ESG TPLH+AS
Sbjct: 360 KGAKPNSRALNGFTPLHIACKKNHVRVMELLL----KTG--ASIDAVTESGLTPLHVASF 413
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
G+ I + L++ G+ P++ N +T A +V K N + +
Sbjct: 414 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTP 473
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYS 726
+ C + + + L L+ + + + T + L I + + LA ++
Sbjct: 474 LHC-AARIGHTNMVKLLLENNANPNLATTAGHTPL--HIAAREGHVETVLAL----LEKE 526
Query: 727 AFIAPDKEKSNSLCHPLCECQYCK-RKTESCTDFDV--NVCDSNGFTALHYAARYGLDEF 783
A A +K + H +Y K R E + D N NG T LH A + +
Sbjct: 527 ASQACMTKKGFTPLH--VAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDI 584
Query: 784 CNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASE 843
+L+ + + TPLH+AA N+ V R LL G + NA V TPLH A++
Sbjct: 585 VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQ 644
Query: 844 TGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
G+ +LLS + L N + T L + + H+ + D++
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVL 687
Score = 101 bits (242), Expect = 1e-20
Identities = 102/425 (24%), Positives = 175/425 (41%), Gaps = 32/425 (7%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G TALH+A++ G+ +V L+ G+ +NA + L+ A+ H V+ LL +GAN
Sbjct: 78 GNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQ 137
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI----------------------- 588
N D TPL +A+ GH + V +I + ++
Sbjct: 138 NVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 197
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
N + +++G TPLH+A+ + +A+LL+ G+ + T A + +++
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 257
Query: 649 CTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRA 708
+ T E+ + C + +++ + L A KT L I +
Sbjct: 258 LLDRGAQIETKTKDELTPLHCAARNG-HVRISEILLDHGAPIQA-KTKNGLSPIHMAAQ- 314
Query: 709 ISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCK-RKTESCTDFDVNVCDSN 767
GD L C + + Y A I + H C + + K N N
Sbjct: 315 ---GD-HLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 370
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
GFT LH A + +L+ A+++ + TPLH+A+ +++ LL GA+
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 430
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LI 886
N +V TPLH A+ G+ AK LL + ++T L A H ++ L+
Sbjct: 431 NVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL 490
Query: 887 DNYAN 891
+N AN
Sbjct: 491 ENNAN 495
Score = 83.0 bits (196), Expect = 4e-15
Identities = 47/130 (36%), Positives = 69/130 (53%), Gaps = 6/130 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+GLT LHVA H IV+ LL G ++ N + LH A+ + V LL G +
Sbjct: 568 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGS 627
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N +++ TPLHLA GH V ++ ++ N N N+SG TPLHL ++ G+
Sbjct: 628 ANAESVQGVTPLHLAAQEGHAEMVALLL------SKQANGNLGNKSGLTPLHLVAQEGHV 681
Query: 611 GIARLLIEHG 620
+A +LI+HG
Sbjct: 682 PVADVLIKHG 691
Score = 77.0 bits (181), Expect = 3e-13
Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + + +LL+ G NA + + LH A+ GH ++ +LL AN
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N N TPLHL GH+ +I +H + ++ G TPLH+AS +G
Sbjct: 661 GNLGNKSGLTPLHLVAQEGHVPVADVLI---KHG---VMVDATTRMGYTPLHVASHYGNI 714
Query: 611 GIARLLIEHGSE 622
+ + L++H ++
Sbjct: 715 KLVKFLLQHQAD 726
Score = 74.1 bits (174), Expect = 2e-12
Identities = 41/133 (30%), Positives = 66/133 (49%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N C+ NG LH A++ G + L+ + KK T LH+AA+ + V+R
Sbjct: 37 DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRE 96
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L++ GAN+NA TPL+ A++ ++ K LL + + T LAVA + H
Sbjct: 97 LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGH 156
Query: 880 LTIIDLIDNYANK 892
++ + NY K
Sbjct: 157 ENVVAHLINYGTK 169
Score = 72.1 bits (169), Expect = 8e-12
Identities = 46/134 (34%), Positives = 69/134 (51%), Gaps = 6/134 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ +GL LH+AS G +V LL + T +ALH A+ G V+ L++ G
Sbjct: 42 NQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYG 101
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN+N ++ TPL++A HL VK F +G N N A E G TPL +A + G
Sbjct: 102 ANVNAQSQKGFTPLYMAAQENHLEVVK----FLLENG--ANQNVATEDGFTPLAVALQQG 155
Query: 609 YEGIARLLIEHGSE 622
+E + LI +G++
Sbjct: 156 HENVVAHLINYGTK 169
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/141 (31%), Positives = 68/141 (48%), Gaps = 1/141 (0%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
T ++ +G T LH A+ G L+ A+ N N K +TPLH+AA T V
Sbjct: 393 TGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEV 452
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+ LL N A +NA TPLH A+ G+ K+LL N + L T L +A
Sbjct: 453 AKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAR 512
Query: 877 KVHL-TIIDLIDNYANKYANT 896
+ H+ T++ L++ A++ T
Sbjct: 513 EGHVETVLALLEKEASQACMT 533
Score = 70.5 bits (165), Expect = 2e-11
Identities = 42/119 (35%), Positives = 57/119 (47%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G T LH AA+ G E +L+ +AN N NK TPLHL A V +L+ +G +
Sbjct: 635 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMV 694
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+A TPLH AS GNI K LL + D+ + L A + H I+ L+
Sbjct: 695 DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Score = 63.3 bits (147), Expect = 4e-09
Identities = 45/127 (35%), Positives = 61/127 (48%), Gaps = 1/127 (0%)
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
ALH AAR +L+ N N + +K TPLH+AA V +LLL+ GA++N
Sbjct: 176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 831 DVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNY 889
TPLH AS GN+ ++LL I E T L A H+ I + L+D+
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHG 295
Query: 890 ANKYANT 896
A A T
Sbjct: 296 APIQAKT 302
Score = 62.9 bits (146), Expect = 5e-09
Identities = 33/101 (32%), Positives = 52/101 (51%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+T LH A+ YG + L+ ++A+VN + K +PLH AA T ++ LLL NGA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 760
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK 868
N + TPL A G I +L + + + ++K
Sbjct: 761 NEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDK 801
Score = 61.3 bits (142), Expect = 1e-08
Identities = 33/125 (26%), Positives = 65/125 (52%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ + +G T LH A+ G ++LI + V+ + TPLH+A+ +++ LL
Sbjct: 662 NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLL 721
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ A++NA +PLH A++ G+ +LL +++ T LA+AK +++
Sbjct: 722 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYIS 781
Query: 882 IIDLI 886
+ D++
Sbjct: 782 VTDVL 786
Score = 60.9 bits (141), Expect = 2e-08
Identities = 30/80 (37%), Positives = 50/80 (62%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHVAS +G +V+ LL+ +++NA S LH A+ +GH +++ +LL +GA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 760
Query: 552 NQKNIDKNTPLHLAVNNGHL 571
N+ + D TPL +A G++
Sbjct: 761 NEVSSDGTTPLAIAKRLGYI 780
Score = 59.3 bits (137), Expect = 6e-08
Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 1/131 (0%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
NG+T LH AA+ E L+ + N + + TPLHLAA ++ LLL AN
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-L 885
N + + TPLH ++ G++ A +L+ + + T L VA ++ ++ L
Sbjct: 661 GNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 720
Query: 886 IDNYANKYANT 896
+ + A+ A T
Sbjct: 721 LQHQADVNAKT 731
Score = 58.8 bits (136), Expect = 8e-08
Identities = 42/145 (28%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH+ + G + + L++ G ++AT + LH AS G+ ++ LL A++
Sbjct: 668 GLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADV 727
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K +PLH A GH V ++ +G + N + G TPL +A + GY
Sbjct: 728 NAKTKLGYSPLHQAAQQGHTDIVTLLL----KNG--ASPNEVSSDGTTPLAIAKRLGYIS 781
Query: 612 IARLLIEHGSEPS--LQNSYHKTAF 634
+ +L E S L + H+ +F
Sbjct: 782 VTDVLKVVTDETSFVLVSDKHRMSF 806
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/138 (25%), Positives = 66/138 (47%), Gaps = 6/138 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
R++ T+ A+ G L G +IN + N + LH AS GH +++ LLH
Sbjct: 8 READAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHK 67
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
+ NT LH+A G V+ ++ + N+N ++ G TPL++A++
Sbjct: 68 EIILETTTKKGNTALHIAALAGQDEVVRELVNYG------ANVNAQSQKGFTPLYMAAQE 121
Query: 608 GYEGIARLLIEHGSEPSL 625
+ + + L+E+G+ ++
Sbjct: 122 NHLEVVKFLLENGANQNV 139
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Query: 532 ASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
A+ G+ + L L +G +IN N + LHLA GH+ V +++ ++I +
Sbjct: 19 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLH------KEIILE 72
Query: 592 CANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTP 651
+ GNT LH+A+ G + + R L+ +G+ + Q+ T A L+V+K
Sbjct: 73 TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLE 132
Query: 652 N 652
N
Sbjct: 133 N 133
Score = 41.9 bits (94), Expect = 0.010
Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 3/140 (2%)
Query: 759 FDVNVCDSNGFTALHYAARYG-LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+ V +++ T+ AAR G LD+ + L N ++N N+ LHLA+ ++
Sbjct: 3 YSVGFREADAATSFLRAARSGNLDKALDHLR-NGVDINTCNQNGLNGLHLASKEGHVKMV 61
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
LL + NT LH A+ G + L++Y ++ + T L +A +
Sbjct: 62 VELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 121
Query: 878 VHLTIID-LIDNYANKYANT 896
HL ++ L++N AN+ T
Sbjct: 122 NHLEVVKFLLENGANQNVAT 141
Score = 32.3 bits (70), Expect = 7.9
Identities = 17/49 (34%), Positives = 26/49 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
DVN G++ LH AA+ G + +L+ N A+ N + TPL +A
Sbjct: 726 DVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIA 774
>X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for
ankyrin (variant 2.1). ).
Length = 1881
Score = 122 bits (295), Expect = 4e-27
Identities = 100/365 (27%), Positives = 166/365 (45%), Gaps = 14/365 (3%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G+T LH+AS G +V LL+ G++I +E + LH A+ GH + +LL GA
Sbjct: 238 NGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAP 297
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
I K + +P+H+A HL CV+ ++ + I+ TPLH+A+ G+
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQY------DAEIDDITLDHLTPLHVAAHCGHH 351
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCE 670
+A++L++ G++P+ + T A ++V++ +T S + +
Sbjct: 352 RVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVA 411
Query: 671 SEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIA 730
S ++NL + AS + N+K+ + A G ++A + + + + A
Sbjct: 412 SFMGHLPIVKNLLQR-----GASPNVSNVKVETPLHMAARAGHTEVAKYLLQ-NKAKVNA 465
Query: 731 PDKEKSNSLCHPLCECQYCKR-KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
K+ L H + K + + N+ + G T LH AAR G E L+
Sbjct: 466 KAKDDQTPL-HCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLE 524
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
A+ C KK TPLH+AA K V LLL+ A+ NA TPLH A N+
Sbjct: 525 KEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDI 584
Query: 850 AKILL 854
K+LL
Sbjct: 585 VKLLL 589
Score = 117 bits (281), Expect = 2e-25
Identities = 104/403 (25%), Positives = 180/403 (44%), Gaps = 18/403 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
++ +GL+ +H+A+ V LL+ +EI+ L+ + LH A+ GH V +LL
Sbjct: 300 AKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLD 359
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA N + ++ TPLH+A H+ ++ ++ +G +I+ ESG TPLH+AS
Sbjct: 360 KGAKPNSRALNGFTPLHIACKKNHVRVMELLL----KTG--ASIDAVTESGLTPLHVASF 413
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
G+ I + L++ G+ P++ N +T A +V K N + +
Sbjct: 414 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTP 473
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYS 726
+ C + + + L L+ + + + T + L I + + LA ++
Sbjct: 474 LHC-AARIGHTNMVKLLLENNANPNLATTAGHTPL--HIAAREGHVETVLAL----LEKE 526
Query: 727 AFIAPDKEKSNSLCHPLCECQYCK-RKTESCTDFDV--NVCDSNGFTALHYAARYGLDEF 783
A A +K + H +Y K R E + D N NG T LH A + +
Sbjct: 527 ASQACMTKKGFTPLH--VAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDI 584
Query: 784 CNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASE 843
+L+ + + TPLH+AA N+ V R LL G + NA V TPLH A++
Sbjct: 585 VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQ 644
Query: 844 TGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
G+ +LLS + L N + T L + + H+ + D++
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVL 687
Score = 101 bits (242), Expect = 1e-20
Identities = 102/425 (24%), Positives = 175/425 (41%), Gaps = 32/425 (7%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G TALH+A++ G+ +V L+ G+ +NA + L+ A+ H V+ LL +GAN
Sbjct: 78 GNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQ 137
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI----------------------- 588
N D TPL +A+ GH + V +I + ++
Sbjct: 138 NVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 197
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
N + +++G TPLH+A+ + +A+LL+ G+ + T A + +++
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 257
Query: 649 CTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRA 708
+ T E+ + C + +++ + L A KT L I +
Sbjct: 258 LLDRGAQIETKTKDELTPLHCAARNG-HVRISEILLDHGAPIQA-KTKNGLSPIHMAAQ- 314
Query: 709 ISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCK-RKTESCTDFDVNVCDSN 767
GD L C + + Y A I + H C + + K N N
Sbjct: 315 ---GD-HLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 370
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
GFT LH A + +L+ A+++ + TPLH+A+ +++ LL GA+
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 430
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LI 886
N +V TPLH A+ G+ AK LL + ++T L A H ++ L+
Sbjct: 431 NVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL 490
Query: 887 DNYAN 891
+N AN
Sbjct: 491 ENNAN 495
Score = 83.0 bits (196), Expect = 4e-15
Identities = 47/130 (36%), Positives = 69/130 (53%), Gaps = 6/130 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+GLT LHVA H IV+ LL G ++ N + LH A+ + V LL G +
Sbjct: 568 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGS 627
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N +++ TPLHLA GH V ++ ++ N N N+SG TPLHL ++ G+
Sbjct: 628 ANAESVQGVTPLHLAAQEGHAEMVALLL------SKQANGNLGNKSGLTPLHLVAQEGHV 681
Query: 611 GIARLLIEHG 620
+A +LI+HG
Sbjct: 682 PVADVLIKHG 691
Score = 77.0 bits (181), Expect = 3e-13
Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + + +LL+ G NA + + LH A+ GH ++ +LL AN
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N N TPLHL GH+ +I +H + ++ G TPLH+AS +G
Sbjct: 661 GNLGNKSGLTPLHLVAQEGHVPVADVLI---KHG---VMVDATTRMGYTPLHVASHYGNI 714
Query: 611 GIARLLIEHGSE 622
+ + L++H ++
Sbjct: 715 KLVKFLLQHQAD 726
Score = 74.1 bits (174), Expect = 2e-12
Identities = 41/133 (30%), Positives = 66/133 (49%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N C+ NG LH A++ G + L+ + KK T LH+AA+ + V+R
Sbjct: 37 DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRE 96
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L++ GAN+NA TPL+ A++ ++ K LL + + T LAVA + H
Sbjct: 97 LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGH 156
Query: 880 LTIIDLIDNYANK 892
++ + NY K
Sbjct: 157 ENVVAHLINYGTK 169
Score = 72.1 bits (169), Expect = 8e-12
Identities = 46/134 (34%), Positives = 69/134 (51%), Gaps = 6/134 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ +GL LH+AS G +V LL + T +ALH A+ G V+ L++ G
Sbjct: 42 NQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYG 101
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN+N ++ TPL++A HL VK F +G N N A E G TPL +A + G
Sbjct: 102 ANVNAQSQKGFTPLYMAAQENHLEVVK----FLLENG--ANQNVATEDGFTPLAVALQQG 155
Query: 609 YEGIARLLIEHGSE 622
+E + LI +G++
Sbjct: 156 HENVVAHLINYGTK 169
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/141 (31%), Positives = 68/141 (48%), Gaps = 1/141 (0%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
T ++ +G T LH A+ G L+ A+ N N K +TPLH+AA T V
Sbjct: 393 TGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEV 452
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+ LL N A +NA TPLH A+ G+ K+LL N + L T L +A
Sbjct: 453 AKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAR 512
Query: 877 KVHL-TIIDLIDNYANKYANT 896
+ H+ T++ L++ A++ T
Sbjct: 513 EGHVETVLALLEKEASQACMT 533
Score = 70.5 bits (165), Expect = 2e-11
Identities = 42/119 (35%), Positives = 57/119 (47%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G T LH AA+ G E +L+ +AN N NK TPLHL A V +L+ +G +
Sbjct: 635 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMV 694
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+A TPLH AS GNI K LL + D+ + L A + H I+ L+
Sbjct: 695 DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Score = 63.3 bits (147), Expect = 4e-09
Identities = 45/127 (35%), Positives = 61/127 (48%), Gaps = 1/127 (0%)
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
ALH AAR +L+ N N + +K TPLH+AA V +LLL+ GA++N
Sbjct: 176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 831 DVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNY 889
TPLH AS GN+ ++LL I E T L A H+ I + L+D+
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHG 295
Query: 890 ANKYANT 896
A A T
Sbjct: 296 APIQAKT 302
Score = 62.9 bits (146), Expect = 5e-09
Identities = 33/101 (32%), Positives = 52/101 (51%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+T LH A+ YG + L+ ++A+VN + K +PLH AA T ++ LLL NGA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 760
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK 868
N + TPL A G I +L + + + ++K
Sbjct: 761 NEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDK 801
Score = 61.3 bits (142), Expect = 1e-08
Identities = 33/125 (26%), Positives = 65/125 (52%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ + +G T LH A+ G ++LI + V+ + TPLH+A+ +++ LL
Sbjct: 662 NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLL 721
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ A++NA +PLH A++ G+ +LL +++ T LA+AK +++
Sbjct: 722 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYIS 781
Query: 882 IIDLI 886
+ D++
Sbjct: 782 VTDVL 786
Score = 60.9 bits (141), Expect = 2e-08
Identities = 30/80 (37%), Positives = 50/80 (62%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHVAS +G +V+ LL+ +++NA S LH A+ +GH +++ +LL +GA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 760
Query: 552 NQKNIDKNTPLHLAVNNGHL 571
N+ + D TPL +A G++
Sbjct: 761 NEVSSDGTTPLAIAKRLGYI 780
Score = 59.3 bits (137), Expect = 6e-08
Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 1/131 (0%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
NG+T LH AA+ E L+ + N + + TPLHLAA ++ LLL AN
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-L 885
N + + TPLH ++ G++ A +L+ + + T L VA ++ ++ L
Sbjct: 661 GNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 720
Query: 886 IDNYANKYANT 896
+ + A+ A T
Sbjct: 721 LQHQADVNAKT 731
Score = 58.8 bits (136), Expect = 8e-08
Identities = 42/145 (28%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH+ + G + + L++ G ++AT + LH AS G+ ++ LL A++
Sbjct: 668 GLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADV 727
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K +PLH A GH V ++ +G + N + G TPL +A + GY
Sbjct: 728 NAKTKLGYSPLHQAAQQGHTDIVTLLL----KNG--ASPNEVSSDGTTPLAIAKRLGYIS 781
Query: 612 IARLLIEHGSEPS--LQNSYHKTAF 634
+ +L E S L + H+ +F
Sbjct: 782 VTDVLKVVTDETSFVLVSDKHRMSF 806
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/138 (25%), Positives = 66/138 (47%), Gaps = 6/138 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
R++ T+ A+ G L G +IN + N + LH AS GH +++ LLH
Sbjct: 8 READAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHK 67
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
+ NT LH+A G V+ ++ + N+N ++ G TPL++A++
Sbjct: 68 EIILETTTKKGNTALHIAALAGQDEVVRELVNYG------ANVNAQSQKGFTPLYMAAQE 121
Query: 608 GYEGIARLLIEHGSEPSL 625
+ + + L+E+G+ ++
Sbjct: 122 NHLEVVKFLLENGANQNV 139
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Query: 532 ASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
A+ G+ + L L +G +IN N + LHLA GH+ V +++ ++I +
Sbjct: 19 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLH------KEIILE 72
Query: 592 CANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTP 651
+ GNT LH+A+ G + + R L+ +G+ + Q+ T A L+V+K
Sbjct: 73 TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLE 132
Query: 652 N 652
N
Sbjct: 133 N 133
Score = 41.9 bits (94), Expect = 0.010
Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 3/140 (2%)
Query: 759 FDVNVCDSNGFTALHYAARYG-LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+ V +++ T+ AAR G LD+ + L N ++N N+ LHLA+ ++
Sbjct: 3 YSVGFREADAATSFLRAARSGNLDKALDHLR-NGVDINTCNQNGLNGLHLASKEGHVKMV 61
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
LL + NT LH A+ G + L++Y ++ + T L +A +
Sbjct: 62 VELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 121
Query: 878 VHLTIID-LIDNYANKYANT 896
HL ++ L++N AN+ T
Sbjct: 122 NHLEVVKFLLENGANQNVAT 141
Score = 32.3 bits (70), Expect = 7.9
Identities = 17/49 (34%), Positives = 26/49 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
DVN G++ LH AA+ G + +L+ N A+ N + TPL +A
Sbjct: 726 DVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIA 774
>U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein.
Length = 1856
Score = 122 bits (295), Expect = 4e-27
Identities = 100/365 (27%), Positives = 166/365 (45%), Gaps = 14/365 (3%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G+T LH+AS G +V LL+ G++I +E + LH A+ GH + +LL GA
Sbjct: 205 NGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAP 264
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
I K + +P+H+A HL CV+ ++ + I+ TPLH+A+ G+
Sbjct: 265 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQY------DAEIDDITLDHLTPLHVAAHCGHH 318
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCE 670
+A++L++ G++P+ + T A ++V++ +T S + +
Sbjct: 319 RVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVA 378
Query: 671 SEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIA 730
S ++NL + AS + N+K+ + A G ++A + + + + A
Sbjct: 379 SFMGHLPIVKNLLQR-----GASPNVSNVKVETPLHMAARAGHTEVAKYLLQ-NKAKVNA 432
Query: 731 PDKEKSNSLCHPLCECQYCKR-KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
K+ L H + K + + N+ + G T LH AAR G E L+
Sbjct: 433 KAKDDQTPL-HCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLE 491
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
A+ C KK TPLH+AA K V LLL+ A+ NA TPLH A N+
Sbjct: 492 KEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDI 551
Query: 850 AKILL 854
K+LL
Sbjct: 552 VKLLL 556
Score = 117 bits (281), Expect = 2e-25
Identities = 104/403 (25%), Positives = 180/403 (44%), Gaps = 18/403 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
++ +GL+ +H+A+ V LL+ +EI+ L+ + LH A+ GH V +LL
Sbjct: 267 AKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLD 326
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA N + ++ TPLH+A H+ ++ ++ +G +I+ ESG TPLH+AS
Sbjct: 327 KGAKPNSRALNGFTPLHIACKKNHVRVMELLL----KTG--ASIDAVTESGLTPLHVASF 380
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
G+ I + L++ G+ P++ N +T A +V K N + +
Sbjct: 381 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTP 440
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYS 726
+ C + + + L L+ + + + T + L I + + LA ++
Sbjct: 441 LHC-AARIGHTNMVKLLLENNANPNLATTAGHTPL--HIAAREGHVETVLAL----LEKE 493
Query: 727 AFIAPDKEKSNSLCHPLCECQYCK-RKTESCTDFDV--NVCDSNGFTALHYAARYGLDEF 783
A A +K + H +Y K R E + D N NG T LH A + +
Sbjct: 494 ASQACMTKKGFTPLH--VAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDI 551
Query: 784 CNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASE 843
+L+ + + TPLH+AA N+ V R LL G + NA V TPLH A++
Sbjct: 552 VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQ 611
Query: 844 TGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
G+ +LLS + L N + T L + + H+ + D++
Sbjct: 612 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVL 654
Score = 101 bits (242), Expect = 1e-20
Identities = 102/425 (24%), Positives = 175/425 (41%), Gaps = 32/425 (7%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G TALH+A++ G+ +V L+ G+ +NA + L+ A+ H V+ LL +GAN
Sbjct: 45 GNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQ 104
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI----------------------- 588
N D TPL +A+ GH + V +I + ++
Sbjct: 105 NVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 164
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
N + +++G TPLH+A+ + +A+LL+ G+ + T A + +++
Sbjct: 165 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 224
Query: 649 CTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRA 708
+ T E+ + C + +++ + L A KT L I +
Sbjct: 225 LLDRGAQIETKTKDELTPLHCAARNG-HVRISEILLDHGAPIQA-KTKNGLSPIHMAAQ- 281
Query: 709 ISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCK-RKTESCTDFDVNVCDSN 767
GD L C + + Y A I + H C + + K N N
Sbjct: 282 ---GD-HLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 337
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
GFT LH A + +L+ A+++ + TPLH+A+ +++ LL GA+
Sbjct: 338 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 397
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LI 886
N +V TPLH A+ G+ AK LL + ++T L A H ++ L+
Sbjct: 398 NVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL 457
Query: 887 DNYAN 891
+N AN
Sbjct: 458 ENNAN 462
Score = 83.0 bits (196), Expect = 4e-15
Identities = 47/130 (36%), Positives = 69/130 (53%), Gaps = 6/130 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+GLT LHVA H IV+ LL G ++ N + LH A+ + V LL G +
Sbjct: 535 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGS 594
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N +++ TPLHLA GH V ++ ++ N N N+SG TPLHL ++ G+
Sbjct: 595 ANAESVQGVTPLHLAAQEGHAEMVALLL------SKQANGNLGNKSGLTPLHLVAQEGHV 648
Query: 611 GIARLLIEHG 620
+A +LI+HG
Sbjct: 649 PVADVLIKHG 658
Score = 77.0 bits (181), Expect = 3e-13
Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + + +LL+ G NA + + LH A+ GH ++ +LL AN
Sbjct: 568 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 627
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N N TPLHL GH+ +I +H + ++ G TPLH+AS +G
Sbjct: 628 GNLGNKSGLTPLHLVAQEGHVPVADVLI---KHG---VMVDATTRMGYTPLHVASHYGNI 681
Query: 611 GIARLLIEHGSE 622
+ + L++H ++
Sbjct: 682 KLVKFLLQHQAD 693
Score = 74.5 bits (175), Expect = 1e-12
Identities = 40/97 (41%), Positives = 55/97 (56%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N C+ G TALH AA G DE L+ ANVN +++K TPL++AA N V++
Sbjct: 37 DINTCNQKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKF 96
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSY 856
LL+NGAN N TPL A + G+ L++Y
Sbjct: 97 LLENGANQNVATEDGFTPLAVALQQGHENVVAHLINY 133
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/141 (31%), Positives = 68/141 (48%), Gaps = 1/141 (0%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
T ++ +G T LH A+ G L+ A+ N N K +TPLH+AA T V
Sbjct: 360 TGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEV 419
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+ LL N A +NA TPLH A+ G+ K+LL N + L T L +A
Sbjct: 420 AKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAR 479
Query: 877 KVHL-TIIDLIDNYANKYANT 896
+ H+ T++ L++ A++ T
Sbjct: 480 EGHVETVLALLEKEASQACMT 500
Score = 70.5 bits (165), Expect = 2e-11
Identities = 42/119 (35%), Positives = 57/119 (47%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G T LH AA+ G E +L+ +AN N NK TPLHL A V +L+ +G +
Sbjct: 602 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMV 661
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+A TPLH AS GNI K LL + D+ + L A + H I+ L+
Sbjct: 662 DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 720
Score = 63.3 bits (147), Expect = 4e-09
Identities = 42/135 (31%), Positives = 70/135 (51%), Gaps = 2/135 (1%)
Query: 759 FDVNVCDSNGFTALHYAARYG-LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+ V +++ T+ AAR G LD+ + L N ++N N+K T LH+AA+ + V+
Sbjct: 3 YSVGFREADAATSFLRAARSGNLDKALDHLR-NGVDINTCNQKGNTALHIAALAGQDEVV 61
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
R L++ GAN+NA TPL+ A++ ++ K LL + + T LAVA +
Sbjct: 62 RELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQ 121
Query: 878 VHLTIIDLIDNYANK 892
H ++ + NY K
Sbjct: 122 GHENVVAHLINYGTK 136
Score = 63.3 bits (147), Expect = 4e-09
Identities = 45/127 (35%), Positives = 61/127 (48%), Gaps = 1/127 (0%)
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
ALH AAR +L+ N N + +K TPLH+AA V +LLL+ GA++N
Sbjct: 143 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 202
Query: 831 DVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNY 889
TPLH AS GN+ ++LL I E T L A H+ I + L+D+
Sbjct: 203 PQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHG 262
Query: 890 ANKYANT 896
A A T
Sbjct: 263 APIQAKT 269
Score = 62.9 bits (146), Expect = 5e-09
Identities = 43/135 (31%), Positives = 67/135 (49%), Gaps = 6/135 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
R++ T+ A+ G L G +IN + +ALH A+ G V+ L++
Sbjct: 8 READAATSFLRAARSGNLDKALDHLRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNY 67
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GAN+N ++ TPL++A HL VK F +G N N A E G TPL +A +
Sbjct: 68 GANVNAQSQKGFTPLYMAAQENHLEVVK----FLLENG--ANQNVATEDGFTPLAVALQQ 121
Query: 608 GYEGIARLLIEHGSE 622
G+E + LI +G++
Sbjct: 122 GHENVVAHLINYGTK 136
Score = 62.9 bits (146), Expect = 5e-09
Identities = 33/101 (32%), Positives = 52/101 (51%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+T LH A+ YG + L+ ++A+VN + K +PLH AA T ++ LLL NGA+
Sbjct: 668 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 727
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK 868
N + TPL A G I +L + + + ++K
Sbjct: 728 NEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDK 768
Score = 61.3 bits (142), Expect = 1e-08
Identities = 33/125 (26%), Positives = 65/125 (52%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ + +G T LH A+ G ++LI + V+ + TPLH+A+ +++ LL
Sbjct: 629 NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLL 688
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ A++NA +PLH A++ G+ +LL +++ T LA+AK +++
Sbjct: 689 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYIS 748
Query: 882 IIDLI 886
+ D++
Sbjct: 749 VTDVL 753
Score = 60.9 bits (141), Expect = 2e-08
Identities = 30/80 (37%), Positives = 50/80 (62%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHVAS +G +V+ LL+ +++NA S LH A+ +GH +++ +LL +GA+
Sbjct: 668 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 727
Query: 552 NQKNIDKNTPLHLAVNNGHL 571
N+ + D TPL +A G++
Sbjct: 728 NEVSSDGTTPLAIAKRLGYI 747
Score = 59.3 bits (137), Expect = 6e-08
Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 1/131 (0%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
NG+T LH AA+ E L+ + N + + TPLHLAA ++ LLL AN
Sbjct: 568 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 627
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-L 885
N + + TPLH ++ G++ A +L+ + + T L VA ++ ++ L
Sbjct: 628 GNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 687
Query: 886 IDNYANKYANT 896
+ + A+ A T
Sbjct: 688 LQHQADVNAKT 698
Score = 58.8 bits (136), Expect = 8e-08
Identities = 42/145 (28%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH+ + G + + L++ G ++AT + LH AS G+ ++ LL A++
Sbjct: 635 GLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADV 694
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K +PLH A GH V ++ +G + N + G TPL +A + GY
Sbjct: 695 NAKTKLGYSPLHQAAQQGHTDIVTLLL----KNG--ASPNEVSSDGTTPLAIAKRLGYIS 748
Query: 612 IARLLIEHGSEPS--LQNSYHKTAF 634
+ +L E S L + H+ +F
Sbjct: 749 VTDVLKVVTDETSFVLVSDKHRMSF 773
Score = 40.7 bits (91), Expect = 0.022
Identities = 21/71 (29%), Positives = 36/71 (50%)
Query: 582 EHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLR 641
+H ++IN N+ GNT LH+A+ G + + R L+ +G+ + Q+ T A
Sbjct: 30 DHLRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQEN 89
Query: 642 ILQVLKSCTPN 652
L+V+K N
Sbjct: 90 HLEVVKFLLEN 100
Score = 32.3 bits (70), Expect = 7.9
Identities = 17/49 (34%), Positives = 26/49 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
DVN G++ LH AA+ G + +L+ N A+ N + TPL +A
Sbjct: 693 DVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIA 741
>M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein.
Length = 1880
Score = 122 bits (295), Expect = 4e-27
Identities = 100/365 (27%), Positives = 166/365 (45%), Gaps = 14/365 (3%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G+T LH+AS G +V LL+ G++I +E + LH A+ GH + +LL GA
Sbjct: 238 NGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAP 297
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
I K + +P+H+A HL CV+ ++ + I+ TPLH+A+ G+
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQY------DAEIDDITLDHLTPLHVAAHCGHH 351
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCE 670
+A++L++ G++P+ + T A ++V++ +T S + +
Sbjct: 352 RVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVA 411
Query: 671 SEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIA 730
S ++NL + AS + N+K+ + A G ++A + + + + A
Sbjct: 412 SFMGHLPIVKNLLQR-----GASPNVSNVKVETPLHMAARAGHTEVAKYLLQ-NKAKVNA 465
Query: 731 PDKEKSNSLCHPLCECQYCKR-KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
K+ L H + K + + N+ + G T LH AAR G E L+
Sbjct: 466 KAKDDQTPL-HCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLE 524
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
A+ C KK TPLH+AA K V LLL+ A+ NA TPLH A N+
Sbjct: 525 KEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDI 584
Query: 850 AKILL 854
K+LL
Sbjct: 585 VKLLL 589
Score = 117 bits (281), Expect = 2e-25
Identities = 104/403 (25%), Positives = 180/403 (44%), Gaps = 18/403 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
++ +GL+ +H+A+ V LL+ +EI+ L+ + LH A+ GH V +LL
Sbjct: 300 AKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLD 359
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA N + ++ TPLH+A H+ ++ ++ +G +I+ ESG TPLH+AS
Sbjct: 360 KGAKPNSRALNGFTPLHIACKKNHVRVMELLL----KTG--ASIDAVTESGLTPLHVASF 413
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
G+ I + L++ G+ P++ N +T A +V K N + +
Sbjct: 414 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTP 473
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYS 726
+ C + + + L L+ + + + T + L I + + LA ++
Sbjct: 474 LHC-AARIGHTNMVKLLLENNANPNLATTAGHTPL--HIAAREGHVETVLAL----LEKE 526
Query: 727 AFIAPDKEKSNSLCHPLCECQYCK-RKTESCTDFDV--NVCDSNGFTALHYAARYGLDEF 783
A A +K + H +Y K R E + D N NG T LH A + +
Sbjct: 527 ASQACMTKKGFTPLH--VAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDI 584
Query: 784 CNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASE 843
+L+ + + TPLH+AA N+ V R LL G + NA V TPLH A++
Sbjct: 585 VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQ 644
Query: 844 TGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
G+ +LLS + L N + T L + + H+ + D++
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVL 687
Score = 102 bits (245), Expect = 5e-21
Identities = 103/425 (24%), Positives = 175/425 (41%), Gaps = 32/425 (7%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G TALH+A++ G+ +V L+ G+ +NA + L+ A+ H V+ LL +GAN
Sbjct: 78 GNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQ 137
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI----------------------- 588
N D TPL +A+ GH + V +I + ++
Sbjct: 138 NVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 197
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
N + +++G TPLH+A+ + +A+LL+ GS + T A + +++
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGSSVNFTPQNGITPLHIASRRGNVIMVRL 257
Query: 649 CTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRA 708
+ T E+ + C + +++ + L A KT L I +
Sbjct: 258 LLDRGAQIETKTKDELTPLHCAARNG-HVRISEILLDHGAPIQA-KTKNGLSPIHMAAQ- 314
Query: 709 ISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCK-RKTESCTDFDVNVCDSN 767
GD L C + + Y A I + H C + + K N N
Sbjct: 315 ---GD-HLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 370
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
GFT LH A + +L+ A+++ + TPLH+A+ +++ LL GA+
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 430
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LI 886
N +V TPLH A+ G+ AK LL + ++T L A H ++ L+
Sbjct: 431 NVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL 490
Query: 887 DNYAN 891
+N AN
Sbjct: 491 ENNAN 495
Score = 83.0 bits (196), Expect = 4e-15
Identities = 47/130 (36%), Positives = 69/130 (53%), Gaps = 6/130 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+GLT LHVA H IV+ LL G ++ N + LH A+ + V LL G +
Sbjct: 568 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGS 627
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N +++ TPLHLA GH V ++ ++ N N N+SG TPLHL ++ G+
Sbjct: 628 ANAESVQGVTPLHLAAQEGHAEMVALLL------SKQANGNLGNKSGLTPLHLVAQEGHV 681
Query: 611 GIARLLIEHG 620
+A +LI+HG
Sbjct: 682 PVADVLIKHG 691
Score = 77.0 bits (181), Expect = 3e-13
Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + + +LL+ G NA + + LH A+ GH ++ +LL AN
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N N TPLHL GH+ +I +H + ++ G TPLH+AS +G
Sbjct: 661 GNLGNKSGLTPLHLVAQEGHVPVADVLI---KHG---VMVDATTRMGYTPLHVASHYGNI 714
Query: 611 GIARLLIEHGSE 622
+ + L++H ++
Sbjct: 715 KLVKFLLQHQAD 726
Score = 74.1 bits (174), Expect = 2e-12
Identities = 41/133 (30%), Positives = 66/133 (49%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N C+ NG LH A++ G + L+ + KK T LH+AA+ + V+R
Sbjct: 37 DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRE 96
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L++ GAN+NA TPL+ A++ ++ K LL + + T LAVA + H
Sbjct: 97 LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGH 156
Query: 880 LTIIDLIDNYANK 892
++ + NY K
Sbjct: 157 ENVVAHLINYGTK 169
Score = 72.1 bits (169), Expect = 8e-12
Identities = 46/134 (34%), Positives = 69/134 (51%), Gaps = 6/134 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ +GL LH+AS G +V LL + T +ALH A+ G V+ L++ G
Sbjct: 42 NQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYG 101
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN+N ++ TPL++A HL VK F +G N N A E G TPL +A + G
Sbjct: 102 ANVNAQSQKGFTPLYMAAQENHLEVVK----FLLENG--ANQNVATEDGFTPLAVALQQG 155
Query: 609 YEGIARLLIEHGSE 622
+E + LI +G++
Sbjct: 156 HENVVAHLINYGTK 169
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/141 (31%), Positives = 68/141 (48%), Gaps = 1/141 (0%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
T ++ +G T LH A+ G L+ A+ N N K +TPLH+AA T V
Sbjct: 393 TGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEV 452
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+ LL N A +NA TPLH A+ G+ K+LL N + L T L +A
Sbjct: 453 AKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAR 512
Query: 877 KVHL-TIIDLIDNYANKYANT 896
+ H+ T++ L++ A++ T
Sbjct: 513 EGHVETVLALLEKEASQACMT 533
Score = 70.5 bits (165), Expect = 2e-11
Identities = 42/119 (35%), Positives = 57/119 (47%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G T LH AA+ G E +L+ +AN N NK TPLHL A V +L+ +G +
Sbjct: 635 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMV 694
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+A TPLH AS GNI K LL + D+ + L A + H I+ L+
Sbjct: 695 DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Score = 62.9 bits (146), Expect = 5e-09
Identities = 33/101 (32%), Positives = 52/101 (51%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+T LH A+ YG + L+ ++A+VN + K +PLH AA T ++ LLL NGA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 760
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK 868
N + TPL A G I +L + + + ++K
Sbjct: 761 NEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDK 801
Score = 62.1 bits (144), Expect = 8e-09
Identities = 44/127 (34%), Positives = 61/127 (48%), Gaps = 1/127 (0%)
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
ALH AAR +L+ N N + +K TPLH+AA V +LLL+ G+++N
Sbjct: 176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGSSVNFT 235
Query: 831 DVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNY 889
TPLH AS GN+ ++LL I E T L A H+ I + L+D+
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHG 295
Query: 890 ANKYANT 896
A A T
Sbjct: 296 APIQAKT 302
Score = 61.3 bits (142), Expect = 1e-08
Identities = 33/125 (26%), Positives = 65/125 (52%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ + +G T LH A+ G ++LI + V+ + TPLH+A+ +++ LL
Sbjct: 662 NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLL 721
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ A++NA +PLH A++ G+ +LL +++ T LA+AK +++
Sbjct: 722 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYIS 781
Query: 882 IIDLI 886
+ D++
Sbjct: 782 VTDVL 786
Score = 60.9 bits (141), Expect = 2e-08
Identities = 30/80 (37%), Positives = 50/80 (62%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHVAS +G +V+ LL+ +++NA S LH A+ +GH +++ +LL +GA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 760
Query: 552 NQKNIDKNTPLHLAVNNGHL 571
N+ + D TPL +A G++
Sbjct: 761 NEVSSDGTTPLAIAKRLGYI 780
Score = 59.3 bits (137), Expect = 6e-08
Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 1/131 (0%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
NG+T LH AA+ E L+ + N + + TPLHLAA ++ LLL AN
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-L 885
N + + TPLH ++ G++ A +L+ + + T L VA ++ ++ L
Sbjct: 661 GNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 720
Query: 886 IDNYANKYANT 896
+ + A+ A T
Sbjct: 721 LQHQADVNAKT 731
Score = 58.8 bits (136), Expect = 8e-08
Identities = 42/145 (28%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH+ + G + + L++ G ++AT + LH AS G+ ++ LL A++
Sbjct: 668 GLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADV 727
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K +PLH A GH V ++ +G + N + G TPL +A + GY
Sbjct: 728 NAKTKLGYSPLHQAAQQGHTDIVTLLL----KNG--ASPNEVSSDGTTPLAIAKRLGYIS 781
Query: 612 IARLLIEHGSEPS--LQNSYHKTAF 634
+ +L E S L + H+ +F
Sbjct: 782 VTDVLKVVTDETSFVLVSDKHRMSF 806
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/138 (25%), Positives = 66/138 (47%), Gaps = 6/138 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
R++ T+ A+ G L G +IN + N + LH AS GH +++ LLH
Sbjct: 8 READAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHK 67
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
+ NT LH+A G V+ ++ + N+N ++ G TPL++A++
Sbjct: 68 EIILETTTKKGNTALHIAALAGQDEVVRELVNYG------ANVNAQSQKGFTPLYMAAQE 121
Query: 608 GYEGIARLLIEHGSEPSL 625
+ + + L+E+G+ ++
Sbjct: 122 NHLEVVKFLLENGANQNV 139
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Query: 532 ASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
A+ G+ + L L +G +IN N + LHLA GH+ V +++ ++I +
Sbjct: 19 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLH------KEIILE 72
Query: 592 CANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTP 651
+ GNT LH+A+ G + + R L+ +G+ + Q+ T A L+V+K
Sbjct: 73 TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLE 132
Query: 652 N 652
N
Sbjct: 133 N 133
Score = 41.9 bits (94), Expect = 0.010
Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 3/140 (2%)
Query: 759 FDVNVCDSNGFTALHYAARYG-LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+ V +++ T+ AAR G LD+ + L N ++N N+ LHLA+ ++
Sbjct: 3 YSVGFREADAATSFLRAARSGNLDKALDHLR-NGVDINTCNQNGLNGLHLASKEGHVKMV 61
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
LL + NT LH A+ G + L++Y ++ + T L +A +
Sbjct: 62 VELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 121
Query: 878 VHLTIID-LIDNYANKYANT 896
HL ++ L++N AN+ T
Sbjct: 122 NHLEVVKFLLENGANQNVAT 141
Score = 32.3 bits (70), Expect = 7.9
Identities = 17/49 (34%), Positives = 26/49 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
DVN G++ LH AA+ G + +L+ N A+ N + TPL +A
Sbjct: 726 DVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIA 774
>AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4
variant protein.
Length = 1899
Score = 122 bits (295), Expect = 4e-27
Identities = 100/365 (27%), Positives = 166/365 (45%), Gaps = 14/365 (3%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G+T LH+AS G +V LL+ G++I +E + LH A+ GH + +LL GA
Sbjct: 273 NGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAP 332
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
I K + +P+H+A HL CV+ ++ + I+ TPLH+A+ G+
Sbjct: 333 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQY------DAEIDDITLDHLTPLHVAAHCGHH 386
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCE 670
+A++L++ G++P+ + T A ++V++ +T S + +
Sbjct: 387 RVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVA 446
Query: 671 SEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIA 730
S ++NL + AS + N+K+ + A G ++A + + + + A
Sbjct: 447 SFMGHLPIVKNLLQR-----GASPNVSNVKVETPLHMAARAGHTEVAKYLLQ-NKAKVNA 500
Query: 731 PDKEKSNSLCHPLCECQYCKR-KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
K+ L H + K + + N+ + G T LH AAR G E L+
Sbjct: 501 KAKDDQTPL-HCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLE 559
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
A+ C KK TPLH+AA K V LLL+ A+ NA TPLH A N+
Sbjct: 560 KEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDI 619
Query: 850 AKILL 854
K+LL
Sbjct: 620 VKLLL 624
Score = 117 bits (281), Expect = 2e-25
Identities = 104/403 (25%), Positives = 180/403 (44%), Gaps = 18/403 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
++ +GL+ +H+A+ V LL+ +EI+ L+ + LH A+ GH V +LL
Sbjct: 335 AKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLD 394
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA N + ++ TPLH+A H+ ++ ++ +G +I+ ESG TPLH+AS
Sbjct: 395 KGAKPNSRALNGFTPLHIACKKNHVRVMELLL----KTG--ASIDAVTESGLTPLHVASF 448
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
G+ I + L++ G+ P++ N +T A +V K N + +
Sbjct: 449 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTP 508
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYS 726
+ C + + + L L+ + + + T + L I + + LA ++
Sbjct: 509 LHC-AARIGHTNMVKLLLENNANPNLATTAGHTPL--HIAAREGHVETVLAL----LEKE 561
Query: 727 AFIAPDKEKSNSLCHPLCECQYCK-RKTESCTDFDV--NVCDSNGFTALHYAARYGLDEF 783
A A +K + H +Y K R E + D N NG T LH A + +
Sbjct: 562 ASQACMTKKGFTPLH--VAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDI 619
Query: 784 CNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASE 843
+L+ + + TPLH+AA N+ V R LL G + NA V TPLH A++
Sbjct: 620 VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQ 679
Query: 844 TGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
G+ +LLS + L N + T L + + H+ + D++
Sbjct: 680 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVL 722
Score = 101 bits (242), Expect = 1e-20
Identities = 102/425 (24%), Positives = 175/425 (41%), Gaps = 32/425 (7%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G TALH+A++ G+ +V L+ G+ +NA + L+ A+ H V+ LL +GAN
Sbjct: 113 GNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQ 172
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI----------------------- 588
N D TPL +A+ GH + V +I + ++
Sbjct: 173 NVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 232
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
N + +++G TPLH+A+ + +A+LL+ G+ + T A + +++
Sbjct: 233 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 292
Query: 649 CTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRA 708
+ T E+ + C + +++ + L A KT L I +
Sbjct: 293 LLDRGAQIETKTKDELTPLHCAARNG-HVRISEILLDHGAPIQA-KTKNGLSPIHMAAQ- 349
Query: 709 ISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCK-RKTESCTDFDVNVCDSN 767
GD L C + + Y A I + H C + + K N N
Sbjct: 350 ---GD-HLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 405
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
GFT LH A + +L+ A+++ + TPLH+A+ +++ LL GA+
Sbjct: 406 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 465
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LI 886
N +V TPLH A+ G+ AK LL + ++T L A H ++ L+
Sbjct: 466 NVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL 525
Query: 887 DNYAN 891
+N AN
Sbjct: 526 ENNAN 530
Score = 83.0 bits (196), Expect = 4e-15
Identities = 47/130 (36%), Positives = 69/130 (53%), Gaps = 6/130 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+GLT LHVA H IV+ LL G ++ N + LH A+ + V LL G +
Sbjct: 603 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGS 662
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N +++ TPLHLA GH V ++ ++ N N N+SG TPLHL ++ G+
Sbjct: 663 ANAESVQGVTPLHLAAQEGHAEMVALLL------SKQANGNLGNKSGLTPLHLVAQEGHV 716
Query: 611 GIARLLIEHG 620
+A +LI+HG
Sbjct: 717 PVADVLIKHG 726
Score = 77.0 bits (181), Expect = 3e-13
Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + + +LL+ G NA + + LH A+ GH ++ +LL AN
Sbjct: 636 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 695
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N N TPLHL GH+ +I +H + ++ G TPLH+AS +G
Sbjct: 696 GNLGNKSGLTPLHLVAQEGHVPVADVLI---KHG---VMVDATTRMGYTPLHVASHYGNI 749
Query: 611 GIARLLIEHGSE 622
+ + L++H ++
Sbjct: 750 KLVKFLLQHQAD 761
Score = 74.1 bits (174), Expect = 2e-12
Identities = 41/133 (30%), Positives = 66/133 (49%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N C+ NG LH A++ G + L+ + KK T LH+AA+ + V+R
Sbjct: 72 DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRE 131
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L++ GAN+NA TPL+ A++ ++ K LL + + T LAVA + H
Sbjct: 132 LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGH 191
Query: 880 LTIIDLIDNYANK 892
++ + NY K
Sbjct: 192 ENVVAHLINYGTK 204
Score = 72.1 bits (169), Expect = 8e-12
Identities = 46/134 (34%), Positives = 69/134 (51%), Gaps = 6/134 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ +GL LH+AS G +V LL + T +ALH A+ G V+ L++ G
Sbjct: 77 NQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYG 136
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN+N ++ TPL++A HL VK F +G N N A E G TPL +A + G
Sbjct: 137 ANVNAQSQKGFTPLYMAAQENHLEVVK----FLLENG--ANQNVATEDGFTPLAVALQQG 190
Query: 609 YEGIARLLIEHGSE 622
+E + LI +G++
Sbjct: 191 HENVVAHLINYGTK 204
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/141 (31%), Positives = 68/141 (48%), Gaps = 1/141 (0%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
T ++ +G T LH A+ G L+ A+ N N K +TPLH+AA T V
Sbjct: 428 TGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEV 487
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+ LL N A +NA TPLH A+ G+ K+LL N + L T L +A
Sbjct: 488 AKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAR 547
Query: 877 KVHL-TIIDLIDNYANKYANT 896
+ H+ T++ L++ A++ T
Sbjct: 548 EGHVETVLALLEKEASQACMT 568
Score = 70.5 bits (165), Expect = 2e-11
Identities = 42/119 (35%), Positives = 57/119 (47%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G T LH AA+ G E +L+ +AN N NK TPLHL A V +L+ +G +
Sbjct: 670 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMV 729
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+A TPLH AS GNI K LL + D+ + L A + H I+ L+
Sbjct: 730 DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 788
Score = 63.3 bits (147), Expect = 4e-09
Identities = 45/127 (35%), Positives = 61/127 (48%), Gaps = 1/127 (0%)
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
ALH AAR +L+ N N + +K TPLH+AA V +LLL+ GA++N
Sbjct: 211 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 270
Query: 831 DVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNY 889
TPLH AS GN+ ++LL I E T L A H+ I + L+D+
Sbjct: 271 PQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHG 330
Query: 890 ANKYANT 896
A A T
Sbjct: 331 APIQAKT 337
Score = 62.9 bits (146), Expect = 5e-09
Identities = 33/101 (32%), Positives = 52/101 (51%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+T LH A+ YG + L+ ++A+VN + K +PLH AA T ++ LLL NGA+
Sbjct: 736 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 795
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK 868
N + TPL A G I +L + + + ++K
Sbjct: 796 NEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDK 836
Score = 61.3 bits (142), Expect = 1e-08
Identities = 33/125 (26%), Positives = 65/125 (52%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ + +G T LH A+ G ++LI + V+ + TPLH+A+ +++ LL
Sbjct: 697 NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLL 756
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ A++NA +PLH A++ G+ +LL +++ T LA+AK +++
Sbjct: 757 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYIS 816
Query: 882 IIDLI 886
+ D++
Sbjct: 817 VTDVL 821
Score = 60.9 bits (141), Expect = 2e-08
Identities = 30/80 (37%), Positives = 50/80 (62%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHVAS +G +V+ LL+ +++NA S LH A+ +GH +++ +LL +GA+
Sbjct: 736 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 795
Query: 552 NQKNIDKNTPLHLAVNNGHL 571
N+ + D TPL +A G++
Sbjct: 796 NEVSSDGTTPLAIAKRLGYI 815
Score = 59.3 bits (137), Expect = 6e-08
Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 1/131 (0%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
NG+T LH AA+ E L+ + N + + TPLHLAA ++ LLL AN
Sbjct: 636 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 695
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-L 885
N + + TPLH ++ G++ A +L+ + + T L VA ++ ++ L
Sbjct: 696 GNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 755
Query: 886 IDNYANKYANT 896
+ + A+ A T
Sbjct: 756 LQHQADVNAKT 766
Score = 58.8 bits (136), Expect = 8e-08
Identities = 42/145 (28%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH+ + G + + L++ G ++AT + LH AS G+ ++ LL A++
Sbjct: 703 GLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADV 762
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K +PLH A GH V ++ +G + N + G TPL +A + GY
Sbjct: 763 NAKTKLGYSPLHQAAQQGHTDIVTLLL----KNG--ASPNEVSSDGTTPLAIAKRLGYIS 816
Query: 612 IARLLIEHGSEPS--LQNSYHKTAF 634
+ +L E S L + H+ +F
Sbjct: 817 VTDVLKVVTDETSFVLVSDKHRMSF 841
Score = 58.0 bits (134), Expect = 1e-07
Identities = 31/114 (27%), Positives = 58/114 (50%), Gaps = 6/114 (5%)
Query: 512 LEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHL 571
L G +IN + N + LH AS GH +++ LLH + NT LH+A G
Sbjct: 67 LRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQD 126
Query: 572 HCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSL 625
V+ ++ + N+N ++ G TPL++A++ + + + L+E+G+ ++
Sbjct: 127 EVVRELVNYG------ANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNV 174
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Query: 532 ASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
A+ G+ + L L +G +IN N + LHLA GH+ V +++ ++I +
Sbjct: 54 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLH------KEIILE 107
Query: 592 CANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTP 651
+ GNT LH+A+ G + + R L+ +G+ + Q+ T A L+V+K
Sbjct: 108 TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLE 167
Query: 652 N 652
N
Sbjct: 168 N 168
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Query: 770 TALHYAARYG-LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
T+ AAR G LD+ + L N ++N N+ LHLA+ ++ LL +
Sbjct: 49 TSFLRAARSGNLDKALDHLR-NGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 107
Query: 829 AIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LID 887
NT LH A+ G + L++Y ++ + T L +A + HL ++ L++
Sbjct: 108 TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLE 167
Query: 888 NYANKYANT 896
N AN+ T
Sbjct: 168 NGANQNVAT 176
Score = 32.3 bits (70), Expect = 7.9
Identities = 17/49 (34%), Positives = 26/49 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
DVN G++ LH AA+ G + +L+ N A+ N + TPL +A
Sbjct: 761 DVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIA 809
>Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein.
Length = 3925
Score = 114 bits (274), Expect = 2e-24
Identities = 108/417 (25%), Positives = 182/417 (43%), Gaps = 35/417 (8%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH A+ G +VE LLE G+ + A N S LH A+ H + LL A +
Sbjct: 299 GLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPV 358
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ +D T LH+A + GH K ++ ++ N N +G TPLH+A K
Sbjct: 359 DDVTLDYLTALHVAAHCGHYRVTKLLL------DKRANPNARALNGFTPLHIACKKNRIK 412
Query: 612 IARLLIEHGSE-----PSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
+ LL+++G+ S H AF N+ +L + +P++ T+ +
Sbjct: 413 VMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAA 472
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIE------NLKLIERILRAISYGDVKLACFY 720
+ + E L L+N L + + + ++++ +L+ +++ D Y
Sbjct: 473 RAGQVEVVRCL-LRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGY 531
Query: 721 MNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGL 780
+ SA +E + L E ++ GFT LH AA+YG
Sbjct: 532 TPLHISA-----REGQVDVASVLLEAGAAH-----------SLATKKGFTPLHVAAKYGS 575
Query: 781 DEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
+ +L+ RA + K TPLH+AA + V LLL+ GA+ +A TPLH
Sbjct: 576 LDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHI 635
Query: 841 ASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANKYANT 896
A++ + A LL+Y + ++ T L +A + H ++ L+D AN + +T
Sbjct: 636 AAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST 692
Score = 110 bits (264), Expect = 2e-23
Identities = 106/402 (26%), Positives = 179/402 (44%), Gaps = 18/402 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G+T LHVAS G +V+ LL+ G +I+A + + LH A+ GH V+ +LL GA
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 324
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ + + +PLH+A H+ CVK ++ +H K ++ T LH+A+ G+
Sbjct: 325 LLARTKNGLSPLHMAAQGDHVECVKHLL---QH---KAPVDDVTLDYLTALHVAAHCGHY 378
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCE 670
+ +LL++ + P+ + T A ++V++ IT S + I
Sbjct: 379 RVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVA 438
Query: 671 SEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLA-CFYMNIDYSAFI 729
+ L + L L+ N AS + N++ + A G V++ C N
Sbjct: 439 AFM-GHLNIVLLLLQ----NGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDAR 493
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
A +++ + L + + + + D +NG+T LH +AR G + ++L+
Sbjct: 494 AREEQTPLHIASRLGKTEIVQLLLQHMAHPD--AATTNGYTPLHISAREGQVDVASVLLE 551
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
A + KK TPLH+AA V +LLL A ++ TPLH A+ N
Sbjct: 552 AGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKV 611
Query: 850 AKILL--SYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
A +LL +P T N T L +A K + I + NY
Sbjct: 612 ALLLLEKGASPHATAKNG--YTPLHIAAKKNQMQIASTLLNY 651
Score = 104 bits (249), Expect = 2e-21
Identities = 102/408 (25%), Positives = 176/408 (43%), Gaps = 19/408 (4%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
LTALHVA+ G + + LL+ + NA LN + LH A + V+ +L+ GA+I
Sbjct: 366 LTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQ 425
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
TP+H+A GHL+ V ++ +G ++ N G T LH+A++ G +
Sbjct: 426 AITESGLTPIHVAAFMGHLNIVLLLL----QNGASPDVT--NIRGETALHMAARAGQVEV 479
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESE 672
R L+ +G+ + +T A L ++++ ++ T++ + S
Sbjct: 480 VRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHI-SA 538
Query: 673 KPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPD 732
+ + + ++ L+ A+ ++ K + A YG + +A + +A D
Sbjct: 539 REGQVDVASVLLEAG----AAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA----D 590
Query: 733 KEKSNSLCHPLCECQYCKRKTESCT---DFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
N L Y +K + NG+T LH AA+ + + L+
Sbjct: 591 SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 650
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
A N K+ TPLHLA+ T ++ LLLD GANI+ + T LH A++ +
Sbjct: 651 YGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNV 710
Query: 850 AKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANKYANT 896
A IL + D T L VA ++ +++ L+ AN A T
Sbjct: 711 ADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKT 758
Score = 101 bits (243), Expect = 9e-21
Identities = 102/397 (25%), Positives = 172/397 (43%), Gaps = 28/397 (7%)
Query: 503 GKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPL 562
G V L+ G +IN + N +ALH A+ GH ++ LL G++++ NT L
Sbjct: 42 GNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTAL 101
Query: 563 HLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSE 622
H+A G VK ++ NIN +++G TPL++A++ + + + L+E+G+
Sbjct: 102 HIASLAGQAEVVKVLV------KEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN 155
Query: 623 PSLQNSYHKT----AFDYAHNLRILQVLKSCTPNLFEY--IHITSSEVKKISCESEKPTS 676
S T A HN + +L++ T +HI + + + K +
Sbjct: 156 QSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARK------DDTKSAA 209
Query: 677 LKLQN-LTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA-FIAPDKE 734
L LQN ++T E+ I A YG+V +A +N + F A +
Sbjct: 210 LLLQNDHNADVQSKMMVNRTTESGFTPLHI--AAHYGNVNVATLLLNRGAAVDFTARNGI 267
Query: 735 KSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANV 794
+ K + D D G T LH AAR G D+ +L+ A +
Sbjct: 268 TPLHVASKRGNTNMVKLLLDRGGQIDAKTRD--GLTPLHCAARSGHDQVVELLLERGAPL 325
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
R K +PLH+AA + ++ LL + A ++ + + T LH A+ G+ K+LL
Sbjct: 326 LARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLL 385
Query: 855 S--YNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
NP+ LN T L +A K + +++L+ Y
Sbjct: 386 DKRANPNARALNGF--TPLHIACKKNRIKVMELLVKY 420
Score = 80.6 bits (190), Expect = 2e-14
Identities = 43/137 (31%), Positives = 76/137 (55%), Gaps = 6/137 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+R +G T LH+A + ++E L++ G+ I A + + +H A+ GH N++L+LL
Sbjct: 393 ARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQ 452
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ + NI T LH+A G + V+ ++ +G ++ E TPLH+AS+
Sbjct: 453 NGASPDVTNIRGETALHMAARAGQVEVVRCLL----RNGALVDARAREE--QTPLHIASR 506
Query: 607 WGYEGIARLLIEHGSEP 623
G I +LL++H + P
Sbjct: 507 LGKTEIVQLLLQHMAHP 523
Score = 80.2 bits (189), Expect = 3e-14
Identities = 47/168 (27%), Positives = 87/168 (51%), Gaps = 6/168 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +R +GL+ LH+A+ V+ LL+ + ++ L+ +ALH A+ GH V +L
Sbjct: 325 LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLL 384
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L AN N + ++ TPLH+A + ++ ++ + +I ESG TP+H+A
Sbjct: 385 LDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYG------ASIQAITESGLTPIHVA 438
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPN 652
+ G+ I LL+++G+ P + N +TA A ++V++ N
Sbjct: 439 AFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRN 486
Score = 76.6 bits (180), Expect = 4e-13
Identities = 45/134 (33%), Positives = 74/134 (55%), Gaps = 6/134 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ +GL ALH+A+ G +V+ LL GS +++ +ALH AS G V+ +L+ G
Sbjct: 61 NQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEG 120
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
ANIN ++ + TPL++A H+ VK Y E+ N + A E G TPL +A + G
Sbjct: 121 ANINAQSQNGFTPLYMAAQENHIDVVK---YLLENGA---NQSTATEDGFTPLAVALQQG 174
Query: 609 YEGIARLLIEHGSE 622
+ +L+E+ ++
Sbjct: 175 HNQAVAILLENDTK 188
Score = 74.1 bits (174), Expect = 2e-12
Identities = 40/128 (31%), Positives = 68/128 (53%), Gaps = 6/128 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ +G + LL G+ ++ T N + LH AS RG+ N++ +LL G I
Sbjct: 233 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQI 292
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ K D TPLH A +GH V+ ++ R + ++G +PLH+A++ +
Sbjct: 293 DAKTRDGLTPLHCAARSGHDQVVELLL------ERGAPLLARTKNGLSPLHMAAQGDHVE 346
Query: 612 IARLLIEH 619
+ L++H
Sbjct: 347 CVKHLLQH 354
Score = 73.3 bits (172), Expect = 3e-12
Identities = 45/136 (33%), Positives = 69/136 (50%), Gaps = 6/136 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
S +GLT LHVA+ + + LLE G+ +AT N + LH A+ + + LL+
Sbjct: 591 SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 650
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA N TPLHLA GH V ++ + NI+ + +SG T LHLA++
Sbjct: 651 YGAETNIVTKQGVTPLHLASQEGHTDMVTLLL------DKGANIHMSTKSGLTSLHLAAQ 704
Query: 607 WGYEGIARLLIEHGSE 622
+A +L +HG++
Sbjct: 705 EDKVNVADILTKHGAD 720
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/155 (29%), Positives = 81/155 (52%), Gaps = 6/155 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G+T LH+AS G +V LL+ G+ I+ + + ++LH A+ NV +L GA+
Sbjct: 662 GVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQ 721
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ TPL +A + G+ VK + + + N+N ++G TPLH A++ G+
Sbjct: 722 DAHTKLGYTPLIVACHYGN---VKMVNFLLKQGA---NVNAKTKNGYTPLHQAAQQGHTH 775
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVL 646
I +L++HG++P+ + TA A L + V+
Sbjct: 776 IINVLLQHGAKPNATTANGNTALAIAKRLGYISVV 810
Score = 67.3 bits (157), Expect = 2e-10
Identities = 37/127 (29%), Positives = 64/127 (50%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
++++ +G T+LH AA+ +IL + A+ + K TPL +A ++
Sbjct: 687 NIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNF 746
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL GAN+NA TPLH A++ G+ +LL + A TALA+AK +
Sbjct: 747 LLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGY 806
Query: 880 LTIIDLI 886
++++D +
Sbjct: 807 ISVVDTL 813
Score = 67.3 bits (157), Expect = 2e-10
Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 6/125 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT+LH+A+ K + + L + G++ +A + L A G+ ++ LL GAN+
Sbjct: 695 GLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANV 754
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K + TPLH A GH H + ++ +H G K N AN GNT L +A + GY
Sbjct: 755 NAKTKNGYTPLHQAAQQGHTHIINVLL---QH-GAKPNATTAN--GNTALAIAKRLGYIS 808
Query: 612 IARLL 616
+ L
Sbjct: 809 VVDTL 813
Score = 65.7 bits (153), Expect = 7e-10
Identities = 34/95 (35%), Positives = 55/95 (57%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
++ S G TALH+AS+ G+A +V+ L++ G+ INA N + L+ A+ H +V+
Sbjct: 89 SVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKY 148
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
LL +GAN + D TPL +A+ GH V ++
Sbjct: 149 LLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 183
Score = 61.7 bits (143), Expect = 1e-08
Identities = 42/122 (34%), Positives = 55/122 (45%), Gaps = 4/122 (3%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+T L A YG + N L+ ANVN + K TPLH AA T +I +LL +GA
Sbjct: 728 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKP 787
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNA--TEKTALAVAKDKVHLTIIDL 885
NA NT L A G I L ++T TEK L V + ++D+
Sbjct: 788 NATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTE--VLDV 845
Query: 886 ID 887
D
Sbjct: 846 SD 847
Score = 60.1 bits (139), Expect = 3e-08
Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
NG T LH A++ G +L+ ++ + + TPLH AA + V+ LLL+ GA
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 324
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-L 885
+ A +PLH A++ ++ K LL + + + TAL VA H + L
Sbjct: 325 LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLL 384
Query: 886 IDNYANKYA 894
+D AN A
Sbjct: 385 LDKRANPNA 393
Score = 59.7 bits (138), Expect = 5e-08
Identities = 38/133 (28%), Positives = 60/133 (45%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+ N+ G T LH A++ G + +L+ AN++ K T LHLAA +K V +
Sbjct: 654 ETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADI 713
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L +GA+ +A TPL A GN+ LL ++ T L A + H
Sbjct: 714 LTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGH 773
Query: 880 LTIIDLIDNYANK 892
II+++ + K
Sbjct: 774 THIINVLLQHGAK 786
Score = 56.0 bits (129), Expect = 6e-07
Identities = 37/136 (27%), Positives = 66/136 (48%), Gaps = 6/136 (4%)
Query: 490 SHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGA 549
++G T LH+++ G+ + LLE G+ + + LH A+ G +V +LL A
Sbjct: 528 TNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRA 587
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ + TPLH+A H K + E + + + ++G TPLH+A+K
Sbjct: 588 AADSAGKNGLTPLHVA---AHYDNQKVALLLLE---KGASPHATAKNGYTPLHIAAKKNQ 641
Query: 610 EGIARLLIEHGSEPSL 625
IA L+ +G+E ++
Sbjct: 642 MQIASTLLNYGAETNI 657
Score = 52.4 bits (120), Expect = 7e-06
Identities = 36/140 (25%), Positives = 68/140 (48%), Gaps = 8/140 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++ +G T L++A+ +V+ LLE G+ + + + L A +GH + +L
Sbjct: 123 INAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAIL 182
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG---RKININCANESGNTPL 601
L + + K + LH+A A++ +H+ K+ +N ESG TPL
Sbjct: 183 LEN----DTKGKVRLPALHIAARKDDTKSA-ALLLQNDHNADVQSKMMVNRTTESGFTPL 237
Query: 602 HLASKWGYEGIARLLIEHGS 621
H+A+ +G +A LL+ G+
Sbjct: 238 HIAAHYGNVNVATLLLNRGA 257
Score = 50.4 bits (115), Expect = 3e-05
Identities = 33/121 (27%), Positives = 59/121 (48%), Gaps = 6/121 (4%)
Query: 532 ASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
A+ G+ + ++ L G +IN N + LHLA GH+ V+ ++ GR +++
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELL------GRGSSVD 91
Query: 592 CANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTP 651
A + GNT LH+AS G + ++L++ G+ + Q+ T A + V+K
Sbjct: 92 SATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLE 151
Query: 652 N 652
N
Sbjct: 152 N 152
Score = 48.8 bits (111), Expect = 8e-05
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 3/124 (2%)
Query: 775 AARYG-LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVA 833
AAR G LD+ L ++N N+ LHLAA +++ LL G+++++
Sbjct: 38 AARAGNLDKVVEYLK-GGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKK 96
Query: 834 RNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANK 892
NT LH AS G K+L+ +I + T L +A + H+ ++ L++N AN+
Sbjct: 97 GNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQ 156
Query: 893 YANT 896
T
Sbjct: 157 STAT 160
Score = 36.3 bits (80), Expect = 0.48
Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 2/103 (1%)
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKA--IIYFAEHSGRKININCANESGNTPLHLA 604
SG N + + P N L +A + E+ I+IN N++G LHLA
Sbjct: 12 SGEKFNGSSQRRKRPKKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLA 71
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+K G+ G+ + L+ GS TA A +V+K
Sbjct: 72 AKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVK 114
Score = 36.3 bits (80), Expect = 0.48
Identities = 19/57 (33%), Positives = 32/57 (56%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVL 541
+ ++ +G T LH A+ G I+ LL+ G++ NAT N +AL A G+ +V+
Sbjct: 754 VNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVV 810
>X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein.
Length = 1872
Score = 114 bits (274), Expect = 2e-24
Identities = 108/417 (25%), Positives = 182/417 (43%), Gaps = 35/417 (8%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH A+ G +VE LLE G+ + A N S LH A+ H + LL A +
Sbjct: 299 GLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPV 358
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ +D T LH+A + GH K ++ ++ N N +G TPLH+A K
Sbjct: 359 DDVTLDYLTALHVAAHCGHYRVTKLLL------DKRANPNARALNGFTPLHIACKKNRIK 412
Query: 612 IARLLIEHGSE-----PSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
+ LL+++G+ S H AF N+ +L + +P++ T+ +
Sbjct: 413 VMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAA 472
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIE------NLKLIERILRAISYGDVKLACFY 720
+ + E L L+N L + + + ++++ +L+ +++ D Y
Sbjct: 473 RAGQVEVVRCL-LRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGY 531
Query: 721 MNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGL 780
+ SA +E + L E ++ GFT LH AA+YG
Sbjct: 532 TPLHISA-----REGQVDVASVLLEAGAAH-----------SLATKKGFTPLHVAAKYGS 575
Query: 781 DEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
+ +L+ RA + K TPLH+AA + V LLL+ GA+ +A TPLH
Sbjct: 576 LDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHI 635
Query: 841 ASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANKYANT 896
A++ + A LL+Y + ++ T L +A + H ++ L+D AN + +T
Sbjct: 636 AAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST 692
Score = 110 bits (264), Expect = 2e-23
Identities = 106/402 (26%), Positives = 179/402 (44%), Gaps = 18/402 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G+T LHVAS G +V+ LL+ G +I+A + + LH A+ GH V+ +LL GA
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 324
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ + + +PLH+A H+ CVK ++ +H K ++ T LH+A+ G+
Sbjct: 325 LLARTKNGLSPLHMAAQGDHVECVKHLL---QH---KAPVDDVTLDYLTALHVAAHCGHY 378
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCE 670
+ +LL++ + P+ + T A ++V++ IT S + I
Sbjct: 379 RVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVA 438
Query: 671 SEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLA-CFYMNIDYSAFI 729
+ L + L L+ N AS + N++ + A G V++ C N
Sbjct: 439 AFM-GHLNIVLLLLQ----NGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDAR 493
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
A +++ + L + + + + D +NG+T LH +AR G + ++L+
Sbjct: 494 AREEQTPLHIASRLGKTEIVQLLLQHMAHPD--AATTNGYTPLHISAREGQVDVASVLLE 551
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
A + KK TPLH+AA V +LLL A ++ TPLH A+ N
Sbjct: 552 AGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKV 611
Query: 850 AKILL--SYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
A +LL +P T N T L +A K + I + NY
Sbjct: 612 ALLLLEKGASPHATAKNG--YTPLHIAAKKNQMQIASTLLNY 651
Score = 104 bits (249), Expect = 2e-21
Identities = 102/408 (25%), Positives = 176/408 (43%), Gaps = 19/408 (4%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
LTALHVA+ G + + LL+ + NA LN + LH A + V+ +L+ GA+I
Sbjct: 366 LTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQ 425
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
TP+H+A GHL+ V ++ +G ++ N G T LH+A++ G +
Sbjct: 426 AITESGLTPIHVAAFMGHLNIVLLLL----QNGASPDVT--NIRGETALHMAARAGQVEV 479
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESE 672
R L+ +G+ + +T A L ++++ ++ T++ + S
Sbjct: 480 VRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHI-SA 538
Query: 673 KPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPD 732
+ + + ++ L+ A+ ++ K + A YG + +A + +A D
Sbjct: 539 REGQVDVASVLLEAG----AAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA----D 590
Query: 733 KEKSNSLCHPLCECQYCKRKTESCT---DFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
N L Y +K + NG+T LH AA+ + + L+
Sbjct: 591 SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 650
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
A N K+ TPLHLA+ T ++ LLLD GANI+ + T LH A++ +
Sbjct: 651 YGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNV 710
Query: 850 AKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANKYANT 896
A IL + D T L VA ++ +++ L+ AN A T
Sbjct: 711 ADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKT 758
Score = 101 bits (243), Expect = 9e-21
Identities = 102/397 (25%), Positives = 172/397 (43%), Gaps = 28/397 (7%)
Query: 503 GKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPL 562
G V L+ G +IN + N +ALH A+ GH ++ LL G++++ NT L
Sbjct: 42 GNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTAL 101
Query: 563 HLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSE 622
H+A G VK ++ NIN +++G TPL++A++ + + + L+E+G+
Sbjct: 102 HIASLAGQAEVVKVLV------KEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN 155
Query: 623 PSLQNSYHKT----AFDYAHNLRILQVLKSCTPNLFEY--IHITSSEVKKISCESEKPTS 676
S T A HN + +L++ T +HI + + + K +
Sbjct: 156 QSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARK------DDTKSAA 209
Query: 677 LKLQN-LTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA-FIAPDKE 734
L LQN ++T E+ I A YG+V +A +N + F A +
Sbjct: 210 LLLQNDHNADVQSKMMVNRTTESGFTPLHI--AAHYGNVNVATLLLNRGAAVDFTARNGI 267
Query: 735 KSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANV 794
+ K + D D G T LH AAR G D+ +L+ A +
Sbjct: 268 TPLHVASKRGNTNMVKLLLDRGGQIDAKTRD--GLTPLHCAARSGHDQVVELLLERGAPL 325
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
R K +PLH+AA + ++ LL + A ++ + + T LH A+ G+ K+LL
Sbjct: 326 LARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLL 385
Query: 855 S--YNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
NP+ LN T L +A K + +++L+ Y
Sbjct: 386 DKRANPNARALNGF--TPLHIACKKNRIKVMELLVKY 420
Score = 80.6 bits (190), Expect = 2e-14
Identities = 43/137 (31%), Positives = 76/137 (55%), Gaps = 6/137 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+R +G T LH+A + ++E L++ G+ I A + + +H A+ GH N++L+LL
Sbjct: 393 ARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQ 452
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ + NI T LH+A G + V+ ++ +G ++ E TPLH+AS+
Sbjct: 453 NGASPDVTNIRGETALHMAARAGQVEVVRCLL----RNGALVDARAREE--QTPLHIASR 506
Query: 607 WGYEGIARLLIEHGSEP 623
G I +LL++H + P
Sbjct: 507 LGKTEIVQLLLQHMAHP 523
Score = 80.2 bits (189), Expect = 3e-14
Identities = 47/168 (27%), Positives = 87/168 (51%), Gaps = 6/168 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +R +GL+ LH+A+ V+ LL+ + ++ L+ +ALH A+ GH V +L
Sbjct: 325 LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLL 384
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L AN N + ++ TPLH+A + ++ ++ + +I ESG TP+H+A
Sbjct: 385 LDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYG------ASIQAITESGLTPIHVA 438
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPN 652
+ G+ I LL+++G+ P + N +TA A ++V++ N
Sbjct: 439 AFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRN 486
Score = 76.6 bits (180), Expect = 4e-13
Identities = 45/134 (33%), Positives = 74/134 (55%), Gaps = 6/134 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ +GL ALH+A+ G +V+ LL GS +++ +ALH AS G V+ +L+ G
Sbjct: 61 NQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEG 120
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
ANIN ++ + TPL++A H+ VK Y E+ N + A E G TPL +A + G
Sbjct: 121 ANINAQSQNGFTPLYMAAQENHIDVVK---YLLENGA---NQSTATEDGFTPLAVALQQG 174
Query: 609 YEGIARLLIEHGSE 622
+ +L+E+ ++
Sbjct: 175 HNQAVAILLENDTK 188
Score = 74.1 bits (174), Expect = 2e-12
Identities = 40/128 (31%), Positives = 68/128 (53%), Gaps = 6/128 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ +G + LL G+ ++ T N + LH AS RG+ N++ +LL G I
Sbjct: 233 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQI 292
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ K D TPLH A +GH V+ ++ R + ++G +PLH+A++ +
Sbjct: 293 DAKTRDGLTPLHCAARSGHDQVVELLL------ERGAPLLARTKNGLSPLHMAAQGDHVE 346
Query: 612 IARLLIEH 619
+ L++H
Sbjct: 347 CVKHLLQH 354
Score = 73.3 bits (172), Expect = 3e-12
Identities = 45/136 (33%), Positives = 69/136 (50%), Gaps = 6/136 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
S +GLT LHVA+ + + LLE G+ +AT N + LH A+ + + LL+
Sbjct: 591 SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 650
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA N TPLHLA GH V ++ + NI+ + +SG T LHLA++
Sbjct: 651 YGAETNIVTKQGVTPLHLASQEGHTDMVTLLL------DKGANIHMSTKSGLTSLHLAAQ 704
Query: 607 WGYEGIARLLIEHGSE 622
+A +L +HG++
Sbjct: 705 EDKVNVADILTKHGAD 720
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/155 (29%), Positives = 81/155 (52%), Gaps = 6/155 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G+T LH+AS G +V LL+ G+ I+ + + ++LH A+ NV +L GA+
Sbjct: 662 GVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQ 721
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ TPL +A + G+ VK + + + N+N ++G TPLH A++ G+
Sbjct: 722 DAHTKLGYTPLIVACHYGN---VKMVNFLLKQGA---NVNAKTKNGYTPLHQAAQQGHTH 775
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVL 646
I +L++HG++P+ + TA A L + V+
Sbjct: 776 IINVLLQHGAKPNATTANGNTALAIAKRLGYISVV 810
Score = 67.3 bits (157), Expect = 2e-10
Identities = 37/127 (29%), Positives = 64/127 (50%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
++++ +G T+LH AA+ +IL + A+ + K TPL +A ++
Sbjct: 687 NIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNF 746
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL GAN+NA TPLH A++ G+ +LL + A TALA+AK +
Sbjct: 747 LLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGY 806
Query: 880 LTIIDLI 886
++++D +
Sbjct: 807 ISVVDTL 813
Score = 67.3 bits (157), Expect = 2e-10
Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 6/125 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT+LH+A+ K + + L + G++ +A + L A G+ ++ LL GAN+
Sbjct: 695 GLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANV 754
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K + TPLH A GH H + ++ +H G K N AN GNT L +A + GY
Sbjct: 755 NAKTKNGYTPLHQAAQQGHTHIINVLL---QH-GAKPNATTAN--GNTALAIAKRLGYIS 808
Query: 612 IARLL 616
+ L
Sbjct: 809 VVDTL 813
Score = 65.7 bits (153), Expect = 7e-10
Identities = 34/95 (35%), Positives = 55/95 (57%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
++ S G TALH+AS+ G+A +V+ L++ G+ INA N + L+ A+ H +V+
Sbjct: 89 SVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKY 148
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
LL +GAN + D TPL +A+ GH V ++
Sbjct: 149 LLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 183
Score = 61.7 bits (143), Expect = 1e-08
Identities = 42/122 (34%), Positives = 55/122 (45%), Gaps = 4/122 (3%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+T L A YG + N L+ ANVN + K TPLH AA T +I +LL +GA
Sbjct: 728 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKP 787
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNA--TEKTALAVAKDKVHLTIIDL 885
NA NT L A G I L ++T TEK L V + ++D+
Sbjct: 788 NATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTE--VLDV 845
Query: 886 ID 887
D
Sbjct: 846 SD 847
Score = 60.1 bits (139), Expect = 3e-08
Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
NG T LH A++ G +L+ ++ + + TPLH AA + V+ LLL+ GA
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 324
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-L 885
+ A +PLH A++ ++ K LL + + + TAL VA H + L
Sbjct: 325 LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLL 384
Query: 886 IDNYANKYA 894
+D AN A
Sbjct: 385 LDKRANPNA 393
Score = 59.7 bits (138), Expect = 5e-08
Identities = 38/133 (28%), Positives = 60/133 (45%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+ N+ G T LH A++ G + +L+ AN++ K T LHLAA +K V +
Sbjct: 654 ETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADI 713
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L +GA+ +A TPL A GN+ LL ++ T L A + H
Sbjct: 714 LTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGH 773
Query: 880 LTIIDLIDNYANK 892
II+++ + K
Sbjct: 774 THIINVLLQHGAK 786
Score = 56.0 bits (129), Expect = 6e-07
Identities = 37/136 (27%), Positives = 66/136 (48%), Gaps = 6/136 (4%)
Query: 490 SHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGA 549
++G T LH+++ G+ + LLE G+ + + LH A+ G +V +LL A
Sbjct: 528 TNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRA 587
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ + TPLH+A H K + E + + + ++G TPLH+A+K
Sbjct: 588 AADSAGKNGLTPLHVA---AHYDNQKVALLLLE---KGASPHATAKNGYTPLHIAAKKNQ 641
Query: 610 EGIARLLIEHGSEPSL 625
IA L+ +G+E ++
Sbjct: 642 MQIASTLLNYGAETNI 657
Score = 52.4 bits (120), Expect = 7e-06
Identities = 36/140 (25%), Positives = 68/140 (48%), Gaps = 8/140 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++ +G T L++A+ +V+ LLE G+ + + + L A +GH + +L
Sbjct: 123 INAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAIL 182
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG---RKININCANESGNTPL 601
L + + K + LH+A A++ +H+ K+ +N ESG TPL
Sbjct: 183 LEN----DTKGKVRLPALHIAARKDDTKSA-ALLLQNDHNADVQSKMMVNRTTESGFTPL 237
Query: 602 HLASKWGYEGIARLLIEHGS 621
H+A+ +G +A LL+ G+
Sbjct: 238 HIAAHYGNVNVATLLLNRGA 257
Score = 50.4 bits (115), Expect = 3e-05
Identities = 33/121 (27%), Positives = 59/121 (48%), Gaps = 6/121 (4%)
Query: 532 ASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
A+ G+ + ++ L G +IN N + LHLA GH+ V+ ++ GR +++
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELL------GRGSSVD 91
Query: 592 CANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTP 651
A + GNT LH+AS G + ++L++ G+ + Q+ T A + V+K
Sbjct: 92 SATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLE 151
Query: 652 N 652
N
Sbjct: 152 N 152
Score = 48.8 bits (111), Expect = 8e-05
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 3/124 (2%)
Query: 775 AARYG-LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVA 833
AAR G LD+ L ++N N+ LHLAA +++ LL G+++++
Sbjct: 38 AARAGNLDKVVEYLK-GGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKK 96
Query: 834 RNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANK 892
NT LH AS G K+L+ +I + T L +A + H+ ++ L++N AN+
Sbjct: 97 GNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQ 156
Query: 893 YANT 896
T
Sbjct: 157 STAT 160
Score = 36.3 bits (80), Expect = 0.48
Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 2/103 (1%)
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKA--IIYFAEHSGRKININCANESGNTPLHLA 604
SG N + + P N L +A + E+ I+IN N++G LHLA
Sbjct: 12 SGEKFNGSSQRRKRPKKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLA 71
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+K G+ G+ + L+ GS TA A +V+K
Sbjct: 72 AKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVK 114
Score = 36.3 bits (80), Expect = 0.48
Identities = 19/57 (33%), Positives = 32/57 (56%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVL 541
+ ++ +G T LH A+ G I+ LL+ G++ NAT N +AL A G+ +V+
Sbjct: 754 VNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVV 810
>BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein
protein.
Length = 1863
Score = 114 bits (274), Expect = 2e-24
Identities = 108/417 (25%), Positives = 182/417 (43%), Gaps = 35/417 (8%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH A+ G +VE LLE G+ + A N S LH A+ H + LL A +
Sbjct: 278 GLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPV 337
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ +D T LH+A + GH K ++ ++ N N +G TPLH+A K
Sbjct: 338 DDVTLDYLTALHVAAHCGHYRVTKLLL------DKRANPNARALNGFTPLHIACKKNRIK 391
Query: 612 IARLLIEHGSE-----PSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
+ LL+++G+ S H AF N+ +L + +P++ T+ +
Sbjct: 392 VMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAA 451
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIE------NLKLIERILRAISYGDVKLACFY 720
+ + E L L+N L + + + ++++ +L+ +++ D Y
Sbjct: 452 RAGQVEVVRCL-LRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGY 510
Query: 721 MNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGL 780
+ SA +E + L E ++ GFT LH AA+YG
Sbjct: 511 TPLHISA-----REGQVDVASVLLEAGAAH-----------SLATKKGFTPLHVAAKYGS 554
Query: 781 DEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
+ +L+ RA + K TPLH+AA + V LLL+ GA+ +A TPLH
Sbjct: 555 LDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHI 614
Query: 841 ASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANKYANT 896
A++ + A LL+Y + ++ T L +A + H ++ L+D AN + +T
Sbjct: 615 AAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST 671
Score = 110 bits (264), Expect = 2e-23
Identities = 106/402 (26%), Positives = 179/402 (44%), Gaps = 18/402 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G+T LHVAS G +V+ LL+ G +I+A + + LH A+ GH V+ +LL GA
Sbjct: 244 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 303
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ + + +PLH+A H+ CVK ++ +H K ++ T LH+A+ G+
Sbjct: 304 LLARTKNGLSPLHMAAQGDHVECVKHLL---QH---KAPVDDVTLDYLTALHVAAHCGHY 357
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCE 670
+ +LL++ + P+ + T A ++V++ IT S + I
Sbjct: 358 RVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVA 417
Query: 671 SEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLA-CFYMNIDYSAFI 729
+ L + L L+ N AS + N++ + A G V++ C N
Sbjct: 418 AFM-GHLNIVLLLLQ----NGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDAR 472
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
A +++ + L + + + + D +NG+T LH +AR G + ++L+
Sbjct: 473 AREEQTPLHIASRLGKTEIVQLLLQHMAHPD--AATTNGYTPLHISAREGQVDVASVLLE 530
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
A + KK TPLH+AA V +LLL A ++ TPLH A+ N
Sbjct: 531 AGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKV 590
Query: 850 AKILL--SYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
A +LL +P T N T L +A K + I + NY
Sbjct: 591 ALLLLEKGASPHATAKNG--YTPLHIAAKKNQMQIASTLLNY 630
Score = 104 bits (249), Expect = 2e-21
Identities = 106/416 (25%), Positives = 179/416 (43%), Gaps = 29/416 (6%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
TM + + L A +VE L+ G +IN + N +ALH A+ GH ++
Sbjct: 3 TMLQKSDSNASFLRAARAGNLDKVVE-YLKGGIDINTCNQNGLNALHLAAKEGHVGLVQE 61
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL G++++ NT LH+A G VK ++ NIN +++G TPL++
Sbjct: 62 LLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLV------KEGANINAQSQNGFTPLYM 115
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKT----AFDYAHNLRILQVLKSCTPNLFEY--I 657
A++ + + + L+E+G+ S T A HN + +L++ T +
Sbjct: 116 AAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPAL 175
Query: 658 HITSSEVKKISCESEKPTSLKLQN-LTLKCSDTNDASKTIENLKLIERILRAISYGDVKL 716
HI + + + K +L LQN ++T E+ I A YG+V +
Sbjct: 176 HIAARK------DDTKSAALLLQNDHNADIQSKMMVNRTTESGFTPLHI--AAHYGNVNV 227
Query: 717 ACFYMNIDYSA-FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYA 775
A +N + F A + + K + D D G T LH A
Sbjct: 228 ATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD--GLTPLHCA 285
Query: 776 ARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARN 835
AR G D+ +L+ A + R K +PLH+AA + ++ LL + A ++ + +
Sbjct: 286 ARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYL 345
Query: 836 TPLHDASETGNIGAAKILLS--YNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
T LH A+ G+ K+LL NP+ LN T L +A K + +++L+ Y
Sbjct: 346 TALHVAAHCGHYRVTKLLLDKRANPNARALNGF--TPLHIACKKNRIKVMELLVKY 399
Score = 104 bits (249), Expect = 2e-21
Identities = 102/408 (25%), Positives = 176/408 (43%), Gaps = 19/408 (4%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
LTALHVA+ G + + LL+ + NA LN + LH A + V+ +L+ GA+I
Sbjct: 345 LTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQ 404
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
TP+H+A GHL+ V ++ +G ++ N G T LH+A++ G +
Sbjct: 405 AITESGLTPIHVAAFMGHLNIVLLLL----QNGASPDVT--NIRGETALHMAARAGQVEV 458
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESE 672
R L+ +G+ + +T A L ++++ ++ T++ + S
Sbjct: 459 VRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHI-SA 517
Query: 673 KPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPD 732
+ + + ++ L+ A+ ++ K + A YG + +A + +A D
Sbjct: 518 REGQVDVASVLLEAG----AAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA----D 569
Query: 733 KEKSNSLCHPLCECQYCKRKTESCT---DFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
N L Y +K + NG+T LH AA+ + + L+
Sbjct: 570 SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 629
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
A N K+ TPLHLA+ T ++ LLLD GANI+ + T LH A++ +
Sbjct: 630 YGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNV 689
Query: 850 AKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANKYANT 896
A IL + D T L VA ++ +++ L+ AN A T
Sbjct: 690 ADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKT 737
Score = 80.6 bits (190), Expect = 2e-14
Identities = 43/137 (31%), Positives = 76/137 (55%), Gaps = 6/137 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+R +G T LH+A + ++E L++ G+ I A + + +H A+ GH N++L+LL
Sbjct: 372 ARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQ 431
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ + NI T LH+A G + V+ ++ +G ++ E TPLH+AS+
Sbjct: 432 NGASPDVTNIRGETALHMAARAGQVEVVRCLL----RNGALVDARAREE--QTPLHIASR 485
Query: 607 WGYEGIARLLIEHGSEP 623
G I +LL++H + P
Sbjct: 486 LGKTEIVQLLLQHMAHP 502
Score = 80.2 bits (189), Expect = 3e-14
Identities = 47/168 (27%), Positives = 87/168 (51%), Gaps = 6/168 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +R +GL+ LH+A+ V+ LL+ + ++ L+ +ALH A+ GH V +L
Sbjct: 304 LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLL 363
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L AN N + ++ TPLH+A + ++ ++ + +I ESG TP+H+A
Sbjct: 364 LDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYG------ASIQAITESGLTPIHVA 417
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPN 652
+ G+ I LL+++G+ P + N +TA A ++V++ N
Sbjct: 418 AFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRN 465
Score = 73.3 bits (172), Expect = 3e-12
Identities = 45/136 (33%), Positives = 69/136 (50%), Gaps = 6/136 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
S +GLT LHVA+ + + LLE G+ +AT N + LH A+ + + LL+
Sbjct: 570 SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 629
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA N TPLHLA GH V ++ + NI+ + +SG T LHLA++
Sbjct: 630 YGAETNIVTKQGVTPLHLASQEGHTDMVTLLL------DKGANIHMSTKSGLTSLHLAAQ 683
Query: 607 WGYEGIARLLIEHGSE 622
+A +L +HG++
Sbjct: 684 EDKVNVADILTKHGAD 699
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/155 (29%), Positives = 81/155 (52%), Gaps = 6/155 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G+T LH+AS G +V LL+ G+ I+ + + ++LH A+ NV +L GA+
Sbjct: 641 GVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQ 700
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ TPL +A + G+ VK + + + N+N ++G TPLH A++ G+
Sbjct: 701 DAHTKLGYTPLIVACHYGN---VKMVNFLLKQGA---NVNAKTKNGYTPLHQAAQQGHTH 754
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVL 646
I +L++HG++P+ + TA A L + V+
Sbjct: 755 IINVLLQHGAKPNATTANGNTALAIAKRLGYISVV 789
Score = 67.3 bits (157), Expect = 2e-10
Identities = 37/127 (29%), Positives = 64/127 (50%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
++++ +G T+LH AA+ +IL + A+ + K TPL +A ++
Sbjct: 666 NIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNF 725
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL GAN+NA TPLH A++ G+ +LL + A TALA+AK +
Sbjct: 726 LLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGY 785
Query: 880 LTIIDLI 886
++++D +
Sbjct: 786 ISVVDTL 792
Score = 67.3 bits (157), Expect = 2e-10
Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 6/125 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT+LH+A+ K + + L + G++ +A + L A G+ ++ LL GAN+
Sbjct: 674 GLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANV 733
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K + TPLH A GH H + ++ +H G K N AN GNT L +A + GY
Sbjct: 734 NAKTKNGYTPLHQAAQQGHTHIINVLL---QH-GAKPNATTAN--GNTALAIAKRLGYIS 787
Query: 612 IARLL 616
+ L
Sbjct: 788 VVDTL 792
Score = 61.7 bits (143), Expect = 1e-08
Identities = 42/122 (34%), Positives = 55/122 (45%), Gaps = 4/122 (3%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+T L A YG + N L+ ANVN + K TPLH AA T +I +LL +GA
Sbjct: 707 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKP 766
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNA--TEKTALAVAKDKVHLTIIDL 885
NA NT L A G I L ++T TEK L V + ++D+
Sbjct: 767 NATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTE--VLDV 824
Query: 886 ID 887
D
Sbjct: 825 SD 826
Score = 59.7 bits (138), Expect = 5e-08
Identities = 38/133 (28%), Positives = 60/133 (45%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+ N+ G T LH A++ G + +L+ AN++ K T LHLAA +K V +
Sbjct: 633 ETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADI 692
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L +GA+ +A TPL A GN+ LL ++ T L A + H
Sbjct: 693 LTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGH 752
Query: 880 LTIIDLIDNYANK 892
II+++ + K
Sbjct: 753 THIINVLLQHGAK 765
Score = 56.0 bits (129), Expect = 6e-07
Identities = 37/136 (27%), Positives = 66/136 (48%), Gaps = 6/136 (4%)
Query: 490 SHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGA 549
++G T LH+++ G+ + LLE G+ + + LH A+ G +V +LL A
Sbjct: 507 TNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRA 566
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ + TPLH+A H K + E + + + ++G TPLH+A+K
Sbjct: 567 AADSAGKNGLTPLHVA---AHYDNQKVALLLLE---KGASPHATAKNGYTPLHIAAKKNQ 620
Query: 610 EGIARLLIEHGSEPSL 625
IA L+ +G+E ++
Sbjct: 621 MQIASTLLNYGAETNI 636
Score = 48.8 bits (111), Expect = 8e-05
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 3/124 (2%)
Query: 775 AARYG-LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVA 833
AAR G LD+ L ++N N+ LHLAA +++ LL G+++++
Sbjct: 17 AARAGNLDKVVEYLK-GGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKK 75
Query: 834 RNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANK 892
NT LH AS G K+L+ +I + T L +A + H+ ++ L++N AN+
Sbjct: 76 GNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQ 135
Query: 893 YANT 896
T
Sbjct: 136 STAT 139
Score = 36.3 bits (80), Expect = 0.48
Identities = 19/57 (33%), Positives = 32/57 (56%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVL 541
+ ++ +G T LH A+ G I+ LL+ G++ NAT N +AL A G+ +V+
Sbjct: 733 VNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVV 789
>AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 111 bits (268), Expect = 8e-24
Identities = 103/405 (25%), Positives = 182/405 (44%), Gaps = 24/405 (5%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A + ++E LL+ G+ I A + + +H A+ GH N++ L+H GA+
Sbjct: 399 NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 458
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N N+ T LH+A +G V+ ++ G ++ ++ TPLH++++ G
Sbjct: 459 PNTTNVRGETALHMAARSGQAEVVRYLV----QDGAQVEAKAKDD--QTPLHISARLGKA 512
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEY---IHITSSEVKKI 667
I + L++ G+ P N+ + + H L + + L ++ + IT+ +
Sbjct: 513 DIVQQLLQQGASP---NAATTSGYTPLH-LSAREGHEDVAAFLLDHGASLSITTKKGFTP 568
Query: 668 SCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA 727
+ K L++ NL L+ S + DA+ + + A Y + K+A ++ S
Sbjct: 569 LHVAAKYGKLEVANLLLQKSASPDAA----GKSGLTPLHVAAHYDNQKVALLLLDQGASP 624
Query: 728 FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNIL 787
A K L + Q T D N G ++H AA+ G + ++L
Sbjct: 625 HAAA-KNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683
Query: 788 IFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
+ ANV+ TPLHLAA ++ V +L++ GA+++A TPLH GNI
Sbjct: 684 LGRNANVS-----GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNI 738
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYAN 891
LL ++ + T L A + H II+ L+ N A+
Sbjct: 739 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNAS 783
Score = 109 bits (263), Expect = 3e-23
Identities = 101/414 (24%), Positives = 186/414 (44%), Gaps = 24/414 (5%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
S+ +GL+ LH+A+ V+ LL+ ++ + +ALH A+ GH V +LL
Sbjct: 329 SKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLD 388
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
AN N K ++ TPLH+A + ++ ++ +H +I ESG TP+H+A+
Sbjct: 389 KKANPNAKALNGFTPLHIACKKNRIKVMELLL---KHGA---SIQAVTESGLTPIHVAAF 442
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
G+ I L+ HG+ P+ N +TA A +V++ + + +
Sbjct: 443 MGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTP 502
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKT-IENLKLIERILRAISYGDVKLACFYMNIDY 725
+ + + +Q L + + N A+ + L L R G +A F +D+
Sbjct: 503 LHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAR------EGHEDVAAFL--LDH 554
Query: 726 SAFIAPDKEKSNSLCHPLCECQYCKRKTESC---TDFDVNVCDSNGFTALHYAARYGLDE 782
A ++ +K + H +Y K + + + +G T LH AA Y +
Sbjct: 555 GASLSITTKKGFTPLH--VAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQK 612
Query: 783 FCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDAS 842
+L+ A+ + K TPLH+AA N+ + LL+ GA+ NA+ +H A+
Sbjct: 613 VALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAA 672
Query: 843 ETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKYANT 896
+ G++ +LL N +++ L LA +D+V++ + L++ A+ A T
Sbjct: 673 QEGHVDMVSLLLGRNANVSGLTPLH---LAAQEDRVNVAEV-LVNQGAHVDAQT 722
Score = 109 bits (262), Expect = 4e-23
Identities = 107/411 (26%), Positives = 177/411 (43%), Gaps = 27/411 (6%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ +G + LL + ++ T N+ + LH AS RG+ N++ +LL GA I
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ K D TPLH +GH V+ ++ R I ++G +PLH+A++ +
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLL------DRAAPILSKTKNGLSPLHMATQGDHLN 348
Query: 612 IARLLIEHG-SEPSLQNSYHKTAFDYAH--NLRILQVL--KSCTPNLFEYIHITSSEVKK 666
+LL++H + N Y AH + ++ +VL K PN T
Sbjct: 349 CVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLH--- 405
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYS 726
I+C K +K+ L LK + AS + I A G V + M+ S
Sbjct: 406 IAC---KKNRIKVMELLLK----HGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 458
Query: 727 AFIAPDK-EKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCN 785
+ E + + + + + + + D T LH +AR G +
Sbjct: 459 PNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQ 516
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
L+ A+ N TPLHL+A V LLD+GA+++ TPLH A++ G
Sbjct: 517 QLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYG 576
Query: 846 NIGAAKILL--SYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKYA 894
+ A +LL S +PD + +A D + ++ L+D A+ +A
Sbjct: 577 KLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALL-LLDQGASPHA 626
Score = 97.5 bits (232), Expect = 2e-19
Identities = 94/384 (24%), Positives = 167/384 (43%), Gaps = 34/384 (8%)
Query: 512 LEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHL 571
++ G +IN + N +ALH AS GH V+ LL AN++ NT LH+A G
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 120
Query: 572 HCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHK 631
VK ++ N+N +++G TPL++A++ + + + L+++G+ SL
Sbjct: 121 EVVKVLV------TNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGF 174
Query: 632 T----AFDYAHNLRILQVLKSCTPNLFEY--IHITSSEVKKISCESEKPTSLKLQNLTLK 685
T A H+ + +L++ T +HI + + + K +L LQ
Sbjct: 175 TPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARK------DDTKAAALLLQ----- 223
Query: 686 CSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA-FIAPDKEKSNSLCHPLC 744
ND + +E+ + A YG++ +A +N + F A + +
Sbjct: 224 ----NDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 279
Query: 745 ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTP 804
K + D D G T LH AR G ++ +L+ A + + K +P
Sbjct: 280 NANMVKLLLDRGAKIDAKTRD--GLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSP 337
Query: 805 LHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL--SYNPDITL 862
LH+A + ++LLL + ++ + T LH A+ G+ AK+LL NP+
Sbjct: 338 LHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKA 397
Query: 863 LNATEKTALAVAKDKVHLTIIDLI 886
LN T L +A K + +++L+
Sbjct: 398 LNGF--TPLHIACKKNRIKVMELL 419
Score = 77.0 bits (181), Expect = 3e-13
Identities = 45/134 (33%), Positives = 76/134 (56%), Gaps = 6/134 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ +GL ALH+AS G +V LL+ + ++A +ALH AS G V+ +L+ +G
Sbjct: 71 NQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNG 130
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN+N ++ + TPL++A HL VK F +G ++ A E G TPL +A + G
Sbjct: 131 ANVNAQSQNGFTPLYMAAQENHLEVVK----FLLDNGASQSL--ATEDGFTPLAVALQQG 184
Query: 609 YEGIARLLIEHGSE 622
++ + LL+E+ ++
Sbjct: 185 HDQVVSLLLENDTK 198
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/168 (26%), Positives = 83/168 (49%), Gaps = 18/168 (10%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + I TLLE G++ NA +++H A+ GH +++ +LL AN
Sbjct: 630 NGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNAN 689
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++ TPLHLA ++ + ++ H ++ + G TPLH+ +G
Sbjct: 690 VSGL-----TPLHLAAQEDRVNVAEVLVNQGAH------VDAQTKMGYTPLHVGCHYGNI 738
Query: 611 GIARLLIEHGSE--PSLQNSY---HKTAFD-YAHNLRILQVLKSCTPN 652
I L++H ++ +N Y H+ A + H + +L + + +PN
Sbjct: 739 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL-LQNNASPN 785
Score = 65.7 bits (153), Expect = 7e-10
Identities = 34/120 (28%), Positives = 58/120 (48%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
+G T LH AA+ +L+ A+V+ + K TPLH+ ++ LL + A
Sbjct: 691 SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAK 750
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+NA TPLH A++ G+ +LL N L TAL +A+ +++++D +
Sbjct: 751 VNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 810
Score = 63.3 bits (147), Expect = 4e-09
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH+A+ + + E L+ G+ ++A + LH G+ ++ LL A +
Sbjct: 692 GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKV 751
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K + TPLH A GH H + ++ S ++ +N GNT L +A + GY
Sbjct: 752 NAKTKNGYTPLHQAAQQGHTHIINVLLQ-NNASPNELTVN-----GNTALGIARRLGYIS 805
Query: 612 IARLL 616
+ L
Sbjct: 806 VVDTL 810
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/93 (31%), Positives = 51/93 (54%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHV +G IV LL+ +++NA N + LH A+ +GH +++ +LL + A+
Sbjct: 725 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASP 784
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHS 584
N+ ++ NT L +A G++ V + E +
Sbjct: 785 NELTVNGNTALGIARRLGYISVVDTLKIVTEET 817
Score = 55.6 bits (128), Expect = 7e-07
Identities = 34/129 (26%), Positives = 62/129 (48%), Gaps = 6/129 (4%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
L ALH+A+ LL+ + + + + LH A+ G+ NV +LL+ A ++
Sbjct: 203 LPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVD 262
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ TPLH+A G+ + VK ++ R I+ G TPLH ++ G+E +
Sbjct: 263 FTARNDITPLHVASKRGNANMVKLLL------DRGAKIDAKTRDGLTPLHCGARSGHEQV 316
Query: 613 ARLLIEHGS 621
+L++ +
Sbjct: 317 VEMLLDRAA 325
Score = 53.6 bits (123), Expect = 3e-06
Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 1/119 (0%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AAR G E I N ++N N+ LHLA+ V+ LL AN++A
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 835 NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANK 892
NT LH AS G K+L++ ++ + T L +A + HL ++ L+DN A++
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQ 166
Score = 43.2 bits (97), Expect = 0.004
Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 4/131 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN NGFT L+ AA+ E L+ N A+ + + TPL +A V+ L
Sbjct: 132 NVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSL 191
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+N R LH A+ + AA +LL + + + + + T L +A +
Sbjct: 192 LLENDTK----GKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGN 247
Query: 880 LTIIDLIDNYA 890
+ + L+ N A
Sbjct: 248 INVATLLLNRA 258
Score = 34.7 bits (76), Expect = 1.5
Identities = 18/48 (37%), Positives = 24/48 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
VN NG+T LH AA+ G N+L+ N A+ N T L +A
Sbjct: 751 VNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIA 798
>AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 111 bits (268), Expect = 8e-24
Identities = 103/405 (25%), Positives = 182/405 (44%), Gaps = 24/405 (5%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A + ++E LL+ G+ I A + + +H A+ GH N++ L+H GA+
Sbjct: 14 NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 73
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N N+ T LH+A +G V+ ++ G ++ ++ TPLH++++ G
Sbjct: 74 PNTTNVRGETALHMAARSGQAEVVRYLV----QDGAQVEAKAKDD--QTPLHISARLGKA 127
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEY---IHITSSEVKKI 667
I + L++ G+ P N+ + + H L + + L ++ + IT+ +
Sbjct: 128 DIVQQLLQQGASP---NAATTSGYTPLH-LSAREGHEDVAAFLLDHGASLSITTKKGFTP 183
Query: 668 SCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA 727
+ K L++ NL L+ S + DA+ + + A Y + K+A ++ S
Sbjct: 184 LHVAAKYGKLEVANLLLQKSASPDAA----GKSGLTPLHVAAHYDNQKVALLLLDQGASP 239
Query: 728 FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNIL 787
A K L + Q T D N G ++H AA+ G + ++L
Sbjct: 240 HAAA-KNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 298
Query: 788 IFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
+ ANV+ TPLHLAA ++ V +L++ GA+++A TPLH GNI
Sbjct: 299 LGRNANVS-----GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNI 353
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYAN 891
LL ++ + T L A + H II+ L+ N A+
Sbjct: 354 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNAS 398
Score = 84.6 bits (200), Expect = 1e-15
Identities = 85/357 (23%), Positives = 157/357 (43%), Gaps = 24/357 (6%)
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL AN N K ++ TPLH+A + ++ ++ +H +I ESG TP+H+
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLL---KHGA---SIQAVTESGLTPIHV 54
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
A+ G+ I L+ HG+ P+ N +TA A +V++ + + +
Sbjct: 55 AAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDD 114
Query: 664 VKKISCESEKPTSLKLQNLTLKCSDTNDASKT-IENLKLIERILRAISYGDVKLACFYMN 722
+ + + +Q L + + N A+ + L L R G +A F +
Sbjct: 115 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAR------EGHEDVAAFLL- 167
Query: 723 IDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCT---DFDVNVCDSNGFTALHYAARYG 779
D+ A ++ +K + H +Y K + + + +G T LH AA Y
Sbjct: 168 -DHGASLSITTKKGFTPLH--VAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 224
Query: 780 LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLH 839
+ +L+ A+ + K TPLH+AA N+ + LL+ GA+ NA+ +H
Sbjct: 225 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVH 284
Query: 840 DASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKYANT 896
A++ G++ +LL N +++ L LA +D+V++ + L++ A+ A T
Sbjct: 285 LAAQEGHVDMVSLLLGRNANVSGLTPLH---LAAQEDRVNVAEV-LVNQGAHVDAQT 337
Score = 82.2 bits (194), Expect = 7e-15
Identities = 85/385 (22%), Positives = 159/385 (41%), Gaps = 23/385 (5%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
LL+ + NA LN + LH A + V+ +LL GA+I TP+H+A GH
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH 630
++ V ++ H G + N N G T LH+A++ G + R L++ G++ +
Sbjct: 61 VNIVSQLM----HHG--ASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDD 114
Query: 631 KTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTN 690
+T + L +++ T+S + + + +++ D +
Sbjct: 115 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGH----EDVAAFLLD-H 169
Query: 691 DASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCK 750
AS +I K + A YG +++A N+ +PD + L Y
Sbjct: 170 GASLSITTKKGFTPLHVAAKYGKLEVA----NLLLQKSASPDAAGKSGLTPLHVAAHYDN 225
Query: 751 RKTESC---TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHL 807
+K + NG+T LH AA+ + L+ A+ N ++ +HL
Sbjct: 226 QKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHL 285
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA ++ LLL AN++ + TPLH A++ + A++L++ +
Sbjct: 286 AAQEGHVDMVSLLLGRNANVSGL-----TPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMG 340
Query: 868 KTALAVAKDKVHLTIIDLIDNYANK 892
T L V ++ I++ + ++ K
Sbjct: 341 YTPLHVGCHYGNIKIVNFLLQHSAK 365
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/168 (26%), Positives = 83/168 (49%), Gaps = 18/168 (10%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + I TLLE G++ NA +++H A+ GH +++ +LL AN
Sbjct: 245 NGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNAN 304
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++ TPLHLA ++ + ++ H ++ + G TPLH+ +G
Sbjct: 305 VSGL-----TPLHLAAQEDRVNVAEVLVNQGAH------VDAQTKMGYTPLHVGCHYGNI 353
Query: 611 GIARLLIEHGSE--PSLQNSY---HKTAFD-YAHNLRILQVLKSCTPN 652
I L++H ++ +N Y H+ A + H + +L + + +PN
Sbjct: 354 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL-LQNNASPN 400
Score = 65.7 bits (153), Expect = 7e-10
Identities = 34/120 (28%), Positives = 58/120 (48%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
+G T LH AA+ +L+ A+V+ + K TPLH+ ++ LL + A
Sbjct: 306 SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAK 365
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+NA TPLH A++ G+ +LL N L TAL +A+ +++++D +
Sbjct: 366 VNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 425
Score = 63.3 bits (147), Expect = 4e-09
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH+A+ + + E L+ G+ ++A + LH G+ ++ LL A +
Sbjct: 307 GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKV 366
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K + TPLH A GH H + ++ S ++ +N GNT L +A + GY
Sbjct: 367 NAKTKNGYTPLHQAAQQGHTHIINVLLQ-NNASPNELTVN-----GNTALGIARRLGYIS 420
Query: 612 IARLL 616
+ L
Sbjct: 421 VVDTL 425
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/93 (31%), Positives = 51/93 (54%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHV +G IV LL+ +++NA N + LH A+ +GH +++ +LL + A+
Sbjct: 340 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASP 399
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHS 584
N+ ++ NT L +A G++ V + E +
Sbjct: 400 NELTVNGNTALGIARRLGYISVVDTLKIVTEET 432
Score = 34.7 bits (76), Expect = 1.5
Identities = 18/48 (37%), Positives = 24/48 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
VN NG+T LH AA+ G N+L+ N A+ N T L +A
Sbjct: 366 VNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIA 413
>AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 111 bits (268), Expect = 8e-24
Identities = 103/405 (25%), Positives = 182/405 (44%), Gaps = 24/405 (5%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A + ++E LL+ G+ I A + + +H A+ GH N++ L+H GA+
Sbjct: 399 NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 458
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N N+ T LH+A +G V+ ++ G ++ ++ TPLH++++ G
Sbjct: 459 PNTTNVRGETALHMAARSGQAEVVRYLV----QDGAQVEAKAKDD--QTPLHISARLGKA 512
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEY---IHITSSEVKKI 667
I + L++ G+ P N+ + + H L + + L ++ + IT+ +
Sbjct: 513 DIVQQLLQQGASP---NAATTSGYTPLH-LSAREGHEDVAAFLLDHGASLSITTKKGFTP 568
Query: 668 SCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA 727
+ K L++ NL L+ S + DA+ + + A Y + K+A ++ S
Sbjct: 569 LHVAAKYGKLEVANLLLQKSASPDAA----GKSGLTPLHVAAHYDNQKVALLLLDQGASP 624
Query: 728 FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNIL 787
A K L + Q T D N G ++H AA+ G + ++L
Sbjct: 625 HAAA-KNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683
Query: 788 IFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
+ ANV+ TPLHLAA ++ V +L++ GA+++A TPLH GNI
Sbjct: 684 LGRNANVS-----GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNI 738
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYAN 891
LL ++ + T L A + H II+ L+ N A+
Sbjct: 739 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNAS 783
Score = 109 bits (263), Expect = 3e-23
Identities = 101/414 (24%), Positives = 186/414 (44%), Gaps = 24/414 (5%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
S+ +GL+ LH+A+ V+ LL+ ++ + +ALH A+ GH V +LL
Sbjct: 329 SKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLD 388
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
AN N K ++ TPLH+A + ++ ++ +H +I ESG TP+H+A+
Sbjct: 389 KKANPNAKALNGFTPLHIACKKNRIKVMELLL---KHGA---SIQAVTESGLTPIHVAAF 442
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
G+ I L+ HG+ P+ N +TA A +V++ + + +
Sbjct: 443 MGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTP 502
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKT-IENLKLIERILRAISYGDVKLACFYMNIDY 725
+ + + +Q L + + N A+ + L L R G +A F +D+
Sbjct: 503 LHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAR------EGHEDVAAFL--LDH 554
Query: 726 SAFIAPDKEKSNSLCHPLCECQYCKRKTESC---TDFDVNVCDSNGFTALHYAARYGLDE 782
A ++ +K + H +Y K + + + +G T LH AA Y +
Sbjct: 555 GASLSITTKKGFTPLH--VAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQK 612
Query: 783 FCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDAS 842
+L+ A+ + K TPLH+AA N+ + LL+ GA+ NA+ +H A+
Sbjct: 613 VALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAA 672
Query: 843 ETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKYANT 896
+ G++ +LL N +++ L LA +D+V++ + L++ A+ A T
Sbjct: 673 QEGHVDMVSLLLGRNANVSGLTPLH---LAAQEDRVNVAEV-LVNQGAHVDAQT 722
Score = 109 bits (262), Expect = 4e-23
Identities = 107/411 (26%), Positives = 177/411 (43%), Gaps = 27/411 (6%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ +G + LL + ++ T N+ + LH AS RG+ N++ +LL GA I
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ K D TPLH +GH V+ ++ R I ++G +PLH+A++ +
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLL------DRAAPILSKTKNGLSPLHMATQGDHLN 348
Query: 612 IARLLIEHG-SEPSLQNSYHKTAFDYAH--NLRILQVL--KSCTPNLFEYIHITSSEVKK 666
+LL++H + N Y AH + ++ +VL K PN T
Sbjct: 349 CVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLH--- 405
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYS 726
I+C K +K+ L LK + AS + I A G V + M+ S
Sbjct: 406 IAC---KKNRIKVMELLLK----HGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 458
Query: 727 AFIAPDK-EKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCN 785
+ E + + + + + + + D T LH +AR G +
Sbjct: 459 PNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQ 516
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
L+ A+ N TPLHL+A V LLD+GA+++ TPLH A++ G
Sbjct: 517 QLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYG 576
Query: 846 NIGAAKILL--SYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKYA 894
+ A +LL S +PD + +A D + ++ L+D A+ +A
Sbjct: 577 KLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALL-LLDQGASPHA 626
Score = 97.5 bits (232), Expect = 2e-19
Identities = 94/384 (24%), Positives = 167/384 (43%), Gaps = 34/384 (8%)
Query: 512 LEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHL 571
++ G +IN + N +ALH AS GH V+ LL AN++ NT LH+A G
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 120
Query: 572 HCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHK 631
VK ++ N+N +++G TPL++A++ + + + L+++G+ SL
Sbjct: 121 EVVKVLV------TNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGF 174
Query: 632 T----AFDYAHNLRILQVLKSCTPNLFEY--IHITSSEVKKISCESEKPTSLKLQNLTLK 685
T A H+ + +L++ T +HI + + + K +L LQ
Sbjct: 175 TPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARK------DDTKAAALLLQ----- 223
Query: 686 CSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA-FIAPDKEKSNSLCHPLC 744
ND + +E+ + A YG++ +A +N + F A + +
Sbjct: 224 ----NDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 279
Query: 745 ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTP 804
K + D D G T LH AR G ++ +L+ A + + K +P
Sbjct: 280 NANMVKLLLDRGAKIDAKTRD--GLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSP 337
Query: 805 LHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL--SYNPDITL 862
LH+A + ++LLL + ++ + T LH A+ G+ AK+LL NP+
Sbjct: 338 LHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKA 397
Query: 863 LNATEKTALAVAKDKVHLTIIDLI 886
LN T L +A K + +++L+
Sbjct: 398 LNGF--TPLHIACKKNRIKVMELL 419
Score = 77.0 bits (181), Expect = 3e-13
Identities = 45/134 (33%), Positives = 76/134 (56%), Gaps = 6/134 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ +GL ALH+AS G +V LL+ + ++A +ALH AS G V+ +L+ +G
Sbjct: 71 NQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNG 130
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN+N ++ + TPL++A HL VK F +G ++ A E G TPL +A + G
Sbjct: 131 ANVNAQSQNGFTPLYMAAQENHLEVVK----FLLDNGASQSL--ATEDGFTPLAVALQQG 184
Query: 609 YEGIARLLIEHGSE 622
++ + LL+E+ ++
Sbjct: 185 HDQVVSLLLENDTK 198
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/168 (26%), Positives = 83/168 (49%), Gaps = 18/168 (10%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + I TLLE G++ NA +++H A+ GH +++ +LL AN
Sbjct: 630 NGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNAN 689
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++ TPLHLA ++ + ++ H ++ + G TPLH+ +G
Sbjct: 690 VSGL-----TPLHLAAQEDRVNVAEVLVNQGAH------VDAQTKMGYTPLHVGCHYGNI 738
Query: 611 GIARLLIEHGSE--PSLQNSY---HKTAFD-YAHNLRILQVLKSCTPN 652
I L++H ++ +N Y H+ A + H + +L + + +PN
Sbjct: 739 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL-LQNNASPN 785
Score = 65.7 bits (153), Expect = 7e-10
Identities = 34/120 (28%), Positives = 58/120 (48%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
+G T LH AA+ +L+ A+V+ + K TPLH+ ++ LL + A
Sbjct: 691 SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAK 750
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+NA TPLH A++ G+ +LL N L TAL +A+ +++++D +
Sbjct: 751 VNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 810
Score = 63.3 bits (147), Expect = 4e-09
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH+A+ + + E L+ G+ ++A + LH G+ ++ LL A +
Sbjct: 692 GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKV 751
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K + TPLH A GH H + ++ S ++ +N GNT L +A + GY
Sbjct: 752 NAKTKNGYTPLHQAAQQGHTHIINVLLQ-NNASPNELTVN-----GNTALGIARRLGYIS 805
Query: 612 IARLL 616
+ L
Sbjct: 806 VVDTL 810
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/93 (31%), Positives = 51/93 (54%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHV +G IV LL+ +++NA N + LH A+ +GH +++ +LL + A+
Sbjct: 725 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASP 784
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHS 584
N+ ++ NT L +A G++ V + E +
Sbjct: 785 NELTVNGNTALGIARRLGYISVVDTLKIVTEET 817
Score = 55.6 bits (128), Expect = 7e-07
Identities = 34/129 (26%), Positives = 62/129 (48%), Gaps = 6/129 (4%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
L ALH+A+ LL+ + + + + LH A+ G+ NV +LL+ A ++
Sbjct: 203 LPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVD 262
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ TPLH+A G+ + VK ++ R I+ G TPLH ++ G+E +
Sbjct: 263 FTARNDITPLHVASKRGNANMVKLLL------DRGAKIDAKTRDGLTPLHCGARSGHEQV 316
Query: 613 ARLLIEHGS 621
+L++ +
Sbjct: 317 VEMLLDRAA 325
Score = 53.6 bits (123), Expect = 3e-06
Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 1/119 (0%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AAR G E I N ++N N+ LHLA+ V+ LL AN++A
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 835 NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANK 892
NT LH AS G K+L++ ++ + T L +A + HL ++ L+DN A++
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQ 166
Score = 43.2 bits (97), Expect = 0.004
Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 4/131 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN NGFT L+ AA+ E L+ N A+ + + TPL +A V+ L
Sbjct: 132 NVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSL 191
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+N R LH A+ + AA +LL + + + + + T L +A +
Sbjct: 192 LLENDTK----GKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGN 247
Query: 880 LTIIDLIDNYA 890
+ + L+ N A
Sbjct: 248 INVATLLLNRA 258
Score = 34.7 bits (76), Expect = 1.5
Identities = 18/48 (37%), Positives = 24/48 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
VN NG+T LH AA+ G N+L+ N A+ N T L +A
Sbjct: 751 VNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIA 798
>AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 111 bits (268), Expect = 8e-24
Identities = 103/405 (25%), Positives = 182/405 (44%), Gaps = 24/405 (5%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A + ++E LL+ G+ I A + + +H A+ GH N++ L+H GA+
Sbjct: 14 NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 73
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N N+ T LH+A +G V+ ++ G ++ ++ TPLH++++ G
Sbjct: 74 PNTTNVRGETALHMAARSGQAEVVRYLV----QDGAQVEAKAKDD--QTPLHISARLGKA 127
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEY---IHITSSEVKKI 667
I + L++ G+ P N+ + + H L + + L ++ + IT+ +
Sbjct: 128 DIVQQLLQQGASP---NAATTSGYTPLH-LSAREGHEDVAAFLLDHGASLSITTKKGFTP 183
Query: 668 SCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA 727
+ K L++ NL L+ S + DA+ + + A Y + K+A ++ S
Sbjct: 184 LHVAAKYGKLEVANLLLQKSASPDAA----GKSGLTPLHVAAHYDNQKVALLLLDQGASP 239
Query: 728 FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNIL 787
A K L + Q T D N G ++H AA+ G + ++L
Sbjct: 240 HAAA-KNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 298
Query: 788 IFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
+ ANV+ TPLHLAA ++ V +L++ GA+++A TPLH GNI
Sbjct: 299 LGRNANVS-----GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNI 353
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYAN 891
LL ++ + T L A + H II+ L+ N A+
Sbjct: 354 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNAS 398
Score = 84.6 bits (200), Expect = 1e-15
Identities = 85/357 (23%), Positives = 157/357 (43%), Gaps = 24/357 (6%)
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL AN N K ++ TPLH+A + ++ ++ +H +I ESG TP+H+
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLL---KHGA---SIQAVTESGLTPIHV 54
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
A+ G+ I L+ HG+ P+ N +TA A +V++ + + +
Sbjct: 55 AAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDD 114
Query: 664 VKKISCESEKPTSLKLQNLTLKCSDTNDASKT-IENLKLIERILRAISYGDVKLACFYMN 722
+ + + +Q L + + N A+ + L L R G +A F +
Sbjct: 115 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAR------EGHEDVAAFLL- 167
Query: 723 IDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCT---DFDVNVCDSNGFTALHYAARYG 779
D+ A ++ +K + H +Y K + + + +G T LH AA Y
Sbjct: 168 -DHGASLSITTKKGFTPLH--VAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 224
Query: 780 LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLH 839
+ +L+ A+ + K TPLH+AA N+ + LL+ GA+ NA+ +H
Sbjct: 225 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVH 284
Query: 840 DASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKYANT 896
A++ G++ +LL N +++ L LA +D+V++ + L++ A+ A T
Sbjct: 285 LAAQEGHVDMVSLLLGRNANVSGLTPLH---LAAQEDRVNVAEV-LVNQGAHVDAQT 337
Score = 82.2 bits (194), Expect = 7e-15
Identities = 85/385 (22%), Positives = 159/385 (41%), Gaps = 23/385 (5%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
LL+ + NA LN + LH A + V+ +LL GA+I TP+H+A GH
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH 630
++ V ++ H G + N N G T LH+A++ G + R L++ G++ +
Sbjct: 61 VNIVSQLM----HHG--ASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDD 114
Query: 631 KTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTN 690
+T + L +++ T+S + + + +++ D +
Sbjct: 115 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGH----EDVAAFLLD-H 169
Query: 691 DASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCK 750
AS +I K + A YG +++A N+ +PD + L Y
Sbjct: 170 GASLSITTKKGFTPLHVAAKYGKLEVA----NLLLQKSASPDAAGKSGLTPLHVAAHYDN 225
Query: 751 RKTESC---TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHL 807
+K + NG+T LH AA+ + L+ A+ N ++ +HL
Sbjct: 226 QKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHL 285
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA ++ LLL AN++ + TPLH A++ + A++L++ +
Sbjct: 286 AAQEGHVDMVSLLLGRNANVSGL-----TPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMG 340
Query: 868 KTALAVAKDKVHLTIIDLIDNYANK 892
T L V ++ I++ + ++ K
Sbjct: 341 YTPLHVGCHYGNIKIVNFLLQHSAK 365
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/168 (26%), Positives = 83/168 (49%), Gaps = 18/168 (10%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + I TLLE G++ NA +++H A+ GH +++ +LL AN
Sbjct: 245 NGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNAN 304
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++ TPLHLA ++ + ++ H ++ + G TPLH+ +G
Sbjct: 305 VSGL-----TPLHLAAQEDRVNVAEVLVNQGAH------VDAQTKMGYTPLHVGCHYGNI 353
Query: 611 GIARLLIEHGSE--PSLQNSY---HKTAFD-YAHNLRILQVLKSCTPN 652
I L++H ++ +N Y H+ A + H + +L + + +PN
Sbjct: 354 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL-LQNNASPN 400
Score = 65.7 bits (153), Expect = 7e-10
Identities = 34/120 (28%), Positives = 58/120 (48%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
+G T LH AA+ +L+ A+V+ + K TPLH+ ++ LL + A
Sbjct: 306 SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAK 365
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+NA TPLH A++ G+ +LL N L TAL +A+ +++++D +
Sbjct: 366 VNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 425
Score = 63.3 bits (147), Expect = 4e-09
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH+A+ + + E L+ G+ ++A + LH G+ ++ LL A +
Sbjct: 307 GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKV 366
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K + TPLH A GH H + ++ S ++ +N GNT L +A + GY
Sbjct: 367 NAKTKNGYTPLHQAAQQGHTHIINVLLQ-NNASPNELTVN-----GNTALGIARRLGYIS 420
Query: 612 IARLL 616
+ L
Sbjct: 421 VVDTL 425
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/93 (31%), Positives = 51/93 (54%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHV +G IV LL+ +++NA N + LH A+ +GH +++ +LL + A+
Sbjct: 340 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASP 399
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHS 584
N+ ++ NT L +A G++ V + E +
Sbjct: 400 NELTVNGNTALGIARRLGYISVVDTLKIVTEET 432
Score = 34.7 bits (76), Expect = 1.5
Identities = 18/48 (37%), Positives = 24/48 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
VN NG+T LH AA+ G N+L+ N A+ N T L +A
Sbjct: 366 VNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIA 413
>AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 111 bits (268), Expect = 8e-24
Identities = 103/405 (25%), Positives = 182/405 (44%), Gaps = 24/405 (5%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A + ++E LL+ G+ I A + + +H A+ GH N++ L+H GA+
Sbjct: 399 NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 458
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N N+ T LH+A +G V+ ++ G ++ ++ TPLH++++ G
Sbjct: 459 PNTTNVRGETALHMAARSGQAEVVRYLV----QDGAQVEAKAKDD--QTPLHISARLGKA 512
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEY---IHITSSEVKKI 667
I + L++ G+ P N+ + + H L + + L ++ + IT+ +
Sbjct: 513 DIVQQLLQQGASP---NAATTSGYTPLH-LSAREGHEDVAAFLLDHGASLSITTKKGFTP 568
Query: 668 SCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA 727
+ K L++ NL L+ S + DA+ + + A Y + K+A ++ S
Sbjct: 569 LHVAAKYGKLEVANLLLQKSASPDAA----GKSGLTPLHVAAHYDNQKVALLLLDQGASP 624
Query: 728 FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNIL 787
A K L + Q T D N G ++H AA+ G + ++L
Sbjct: 625 HAAA-KNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683
Query: 788 IFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
+ ANV+ TPLHLAA ++ V +L++ GA+++A TPLH GNI
Sbjct: 684 LGRNANVS-----GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNI 738
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYAN 891
LL ++ + T L A + H II+ L+ N A+
Sbjct: 739 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNAS 783
Score = 109 bits (263), Expect = 3e-23
Identities = 101/414 (24%), Positives = 186/414 (44%), Gaps = 24/414 (5%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
S+ +GL+ LH+A+ V+ LL+ ++ + +ALH A+ GH V +LL
Sbjct: 329 SKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLD 388
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
AN N K ++ TPLH+A + ++ ++ +H +I ESG TP+H+A+
Sbjct: 389 KKANPNAKALNGFTPLHIACKKNRIKVMELLL---KHGA---SIQAVTESGLTPIHVAAF 442
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
G+ I L+ HG+ P+ N +TA A +V++ + + +
Sbjct: 443 MGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTP 502
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKT-IENLKLIERILRAISYGDVKLACFYMNIDY 725
+ + + +Q L + + N A+ + L L R G +A F +D+
Sbjct: 503 LHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAR------EGHEDVAAFL--LDH 554
Query: 726 SAFIAPDKEKSNSLCHPLCECQYCKRKTESC---TDFDVNVCDSNGFTALHYAARYGLDE 782
A ++ +K + H +Y K + + + +G T LH AA Y +
Sbjct: 555 GASLSITTKKGFTPLH--VAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQK 612
Query: 783 FCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDAS 842
+L+ A+ + K TPLH+AA N+ + LL+ GA+ NA+ +H A+
Sbjct: 613 VALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAA 672
Query: 843 ETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKYANT 896
+ G++ +LL N +++ L LA +D+V++ + L++ A+ A T
Sbjct: 673 QEGHVDMVSLLLGRNANVSGLTPLH---LAAQEDRVNVAEV-LVNQGAHVDAQT 722
Score = 109 bits (262), Expect = 4e-23
Identities = 107/411 (26%), Positives = 177/411 (43%), Gaps = 27/411 (6%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ +G + LL + ++ T N+ + LH AS RG+ N++ +LL GA I
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ K D TPLH +GH V+ ++ R I ++G +PLH+A++ +
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLL------DRAAPILSKTKNGLSPLHMATQGDHLN 348
Query: 612 IARLLIEHG-SEPSLQNSYHKTAFDYAH--NLRILQVL--KSCTPNLFEYIHITSSEVKK 666
+LL++H + N Y AH + ++ +VL K PN T
Sbjct: 349 CVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLH--- 405
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYS 726
I+C K +K+ L LK + AS + I A G V + M+ S
Sbjct: 406 IAC---KKNRIKVMELLLK----HGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 458
Query: 727 AFIAPDK-EKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCN 785
+ E + + + + + + + D T LH +AR G +
Sbjct: 459 PNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQ 516
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
L+ A+ N TPLHL+A V LLD+GA+++ TPLH A++ G
Sbjct: 517 QLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYG 576
Query: 846 NIGAAKILL--SYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKYA 894
+ A +LL S +PD + +A D + ++ L+D A+ +A
Sbjct: 577 KLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALL-LLDQGASPHA 626
Score = 97.5 bits (232), Expect = 2e-19
Identities = 94/384 (24%), Positives = 167/384 (43%), Gaps = 34/384 (8%)
Query: 512 LEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHL 571
++ G +IN + N +ALH AS GH V+ LL AN++ NT LH+A G
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 120
Query: 572 HCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHK 631
VK ++ N+N +++G TPL++A++ + + + L+++G+ SL
Sbjct: 121 EVVKVLV------TNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGF 174
Query: 632 T----AFDYAHNLRILQVLKSCTPNLFEY--IHITSSEVKKISCESEKPTSLKLQNLTLK 685
T A H+ + +L++ T +HI + + + K +L LQ
Sbjct: 175 TPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARK------DDTKAAALLLQ----- 223
Query: 686 CSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA-FIAPDKEKSNSLCHPLC 744
ND + +E+ + A YG++ +A +N + F A + +
Sbjct: 224 ----NDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 279
Query: 745 ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTP 804
K + D D G T LH AR G ++ +L+ A + + K +P
Sbjct: 280 NANMVKLLLDRGAKIDAKTRD--GLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSP 337
Query: 805 LHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL--SYNPDITL 862
LH+A + ++LLL + ++ + T LH A+ G+ AK+LL NP+
Sbjct: 338 LHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKA 397
Query: 863 LNATEKTALAVAKDKVHLTIIDLI 886
LN T L +A K + +++L+
Sbjct: 398 LNGF--TPLHIACKKNRIKVMELL 419
Score = 77.0 bits (181), Expect = 3e-13
Identities = 45/134 (33%), Positives = 76/134 (56%), Gaps = 6/134 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ +GL ALH+AS G +V LL+ + ++A +ALH AS G V+ +L+ +G
Sbjct: 71 NQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNG 130
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN+N ++ + TPL++A HL VK F +G ++ A E G TPL +A + G
Sbjct: 131 ANVNAQSQNGFTPLYMAAQENHLEVVK----FLLDNGASQSL--ATEDGFTPLAVALQQG 184
Query: 609 YEGIARLLIEHGSE 622
++ + LL+E+ ++
Sbjct: 185 HDQVVSLLLENDTK 198
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/168 (26%), Positives = 83/168 (49%), Gaps = 18/168 (10%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + I TLLE G++ NA +++H A+ GH +++ +LL AN
Sbjct: 630 NGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNAN 689
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++ TPLHLA ++ + ++ H ++ + G TPLH+ +G
Sbjct: 690 VSGL-----TPLHLAAQEDRVNVAEVLVNQGAH------VDAQTKMGYTPLHVGCHYGNI 738
Query: 611 GIARLLIEHGSE--PSLQNSY---HKTAFD-YAHNLRILQVLKSCTPN 652
I L++H ++ +N Y H+ A + H + +L + + +PN
Sbjct: 739 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL-LQNNASPN 785
Score = 65.7 bits (153), Expect = 7e-10
Identities = 34/120 (28%), Positives = 58/120 (48%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
+G T LH AA+ +L+ A+V+ + K TPLH+ ++ LL + A
Sbjct: 691 SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAK 750
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+NA TPLH A++ G+ +LL N L TAL +A+ +++++D +
Sbjct: 751 VNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 810
Score = 63.3 bits (147), Expect = 4e-09
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLT LH+A+ + + E L+ G+ ++A + LH G+ ++ LL A +
Sbjct: 692 GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKV 751
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K + TPLH A GH H + ++ S ++ +N GNT L +A + GY
Sbjct: 752 NAKTKNGYTPLHQAAQQGHTHIINVLLQ-NNASPNELTVN-----GNTALGIARRLGYIS 805
Query: 612 IARLL 616
+ L
Sbjct: 806 VVDTL 810
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/93 (31%), Positives = 51/93 (54%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHV +G IV LL+ +++NA N + LH A+ +GH +++ +LL + A+
Sbjct: 725 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASP 784
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHS 584
N+ ++ NT L +A G++ V + E +
Sbjct: 785 NELTVNGNTALGIARRLGYISVVDTLKIVTEET 817
Score = 55.6 bits (128), Expect = 7e-07
Identities = 34/129 (26%), Positives = 62/129 (48%), Gaps = 6/129 (4%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
L ALH+A+ LL+ + + + + LH A+ G+ NV +LL+ A ++
Sbjct: 203 LPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVD 262
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ TPLH+A G+ + VK ++ R I+ G TPLH ++ G+E +
Sbjct: 263 FTARNDITPLHVASKRGNANMVKLLL------DRGAKIDAKTRDGLTPLHCGARSGHEQV 316
Query: 613 ARLLIEHGS 621
+L++ +
Sbjct: 317 VEMLLDRAA 325
Score = 53.6 bits (123), Expect = 3e-06
Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 1/119 (0%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AAR G E I N ++N N+ LHLA+ V+ LL AN++A
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 835 NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANK 892
NT LH AS G K+L++ ++ + T L +A + HL ++ L+DN A++
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQ 166
Score = 43.2 bits (97), Expect = 0.004
Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 4/131 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN NGFT L+ AA+ E L+ N A+ + + TPL +A V+ L
Sbjct: 132 NVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSL 191
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+N R LH A+ + AA +LL + + + + + T L +A +
Sbjct: 192 LLENDTK----GKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGN 247
Query: 880 LTIIDLIDNYA 890
+ + L+ N A
Sbjct: 248 INVATLLLNRA 258
Score = 34.7 bits (76), Expect = 1.5
Identities = 18/48 (37%), Positives = 24/48 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
VN NG+T LH AA+ G N+L+ N A+ N T L +A
Sbjct: 751 VNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIA 798
>AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens
cDNA FLJ39767 fis, clone SPLEN2000607, weakly similar to
ANKYRIN 1. ).
Length = 919
Score = 106 bits (255), Expect = 3e-22
Identities = 108/390 (27%), Positives = 170/390 (43%), Gaps = 25/390 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T LHVA+ +G ++ TL G++ ++ LH A+ H + LL SG
Sbjct: 311 DKDGNTPLHVAARYGHELLINTLRTSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSG 370
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
I+ + T LH A G++ C+K + + SG + + ++ G TPLH A+
Sbjct: 371 FEIDTPDKFGRTCLHAAAAGGNVECIKLL----QSSG--ADFHKKDKCGRTPLHYAAANC 424
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+ L+ G+ + + + +TA YA + K+ N H S E+++
Sbjct: 425 HFHCIETLVTTGANVNETDDWGRTALHYA-AASDMDRNKTILGN----AHDNSEELERAR 479
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAF 728
EK +L L+ L NDA+ +I + + I A +YG + + S F
Sbjct: 480 ELKEKEATLCLEFLL-----QNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGF 534
Query: 729 IAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCN 785
D + S H Q + +S D D+ D G TAL AA G E
Sbjct: 535 EESDSGATKSPLHLAAYNGHHQALEVLLQSLVDLDIR--DEKGRTALDLAAFKGHTECVE 592
Query: 786 ILIFNRANVNCR-NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDV---ARNTPLHDA 841
LI A++ + N +TPLH + IN T+ +RLLL+ N A+DV TPL A
Sbjct: 593 ALINPGASIFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLA 652
Query: 842 SETGNIGAAKILLSYNPDITLLNATEKTAL 871
G+I A +LL ++ ++ TAL
Sbjct: 653 VAYGHIDAVSLLLEKEANVDTVDILGCTAL 682
Score = 101 bits (242), Expect = 1e-20
Identities = 112/437 (25%), Positives = 190/437 (43%), Gaps = 45/437 (10%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYA-SSRGHQNVLLMLLHS 547
DS T LHVA+ G A I+E L+ G+ +NA D + LH A +SR + V +++ HS
Sbjct: 13 DSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHS 72
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAI------IYFAEHSGRKI------------- 588
A++N ++ + TPLH+A N + C + I + ++ GR
Sbjct: 73 -ADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMV 131
Query: 589 --------NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNL 640
NIN ++ LH A+ G+ + LLI HG+E + ++ T A +
Sbjct: 132 NLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASN 191
Query: 641 RILQVLKSCTPNL---FEYIHITSSEVKKISCESEKPTSL-KLQNLTLKCSDTNDASKTI 696
+ V+K NL + I++ + I+C + + + +L + + N+ T
Sbjct: 192 GQINVVKHLL-NLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTP 250
Query: 697 ENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLC-ECQYCKRKTES 755
+ A ++G + C + ++ A + + S H ++ + +T
Sbjct: 251 LHFAA------ASTHGAL---CLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLI 301
Query: 756 CTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTV 815
+++ D +G T LH AARYG + N L + A+ + PLHLAA+N +
Sbjct: 302 QNGGEIDCVDKDGNTPLHVAARYGHELLINTLRTSGADTAKCGIHSMFPLHLAALNAHSD 361
Query: 816 VIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
R LL +G I+ D T LH A+ GN+ K+L S D + +T L A
Sbjct: 362 CCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAA 421
Query: 876 DKVHLTIID-LIDNYAN 891
H I+ L+ AN
Sbjct: 422 ANCHFHCIETLVTTGAN 438
Score = 96.3 bits (229), Expect = 4e-19
Identities = 117/424 (27%), Positives = 184/424 (43%), Gaps = 43/424 (10%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLE-MGSEINATDLNEC-SALHYASSRGHQNVLLMLL 545
RD G ++H A+ +G +E LLE S +D S LH A+ GH L +LL
Sbjct: 503 RDKEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLL 562
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
S +++ ++ T L LA GH CV+A+I + G I + N + TPLH +
Sbjct: 563 QSLVDLDIRDEKGRTALDLAAFKGHTECVEALI----NPGASIFVK-DNVTKRTPLHASV 617
Query: 606 KWGYEGIARLLIEHGSEP---SLQNSYHKT----AFDYAHNLRILQVL-KSCTPNLFEYI 657
G+ RLL+E P ++++ +T A Y H + +L K + + +
Sbjct: 618 INGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDTVDIL 677
Query: 658 HITSSEVKKISCESEKPTSLKLQNLTLKCSDTND------ASKTIENLKLIERILRAISY 711
T+ ++ E L Q +++ C D+ A+ L E + A+S
Sbjct: 678 GCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQMALSE 737
Query: 712 GDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTA 771
D CF N Y+ + + L E Q C RK N FT
Sbjct: 738 ED---CCFKDNQGYTPLHWACYNGNENCIEVLLE-QKCFRK-----------FIGNPFTP 782
Query: 772 LHYAARYGLDEFCNILI--FNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
LH A ++L+ + + V+CR+ K +TPL AA + ++LLL + A +NA
Sbjct: 783 LHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVECLQLLLRHSAPVNA 842
Query: 830 IDVARNTPLHDASETGNIGAAKILL-SYNPDITLLNATEKTALAVAKDKVH----LTIID 884
+D + T L A+E G GA IL+ S D+T+ + T L +A K H L I+D
Sbjct: 843 VDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILD 902
Query: 885 LIDN 888
I +
Sbjct: 903 KIQD 906
Score = 93.5 bits (222), Expect = 3e-18
Identities = 98/377 (25%), Positives = 156/377 (41%), Gaps = 30/377 (7%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T +D G T LH A+ +G+ +V+ LL +G EI+ ++ +ALH A G V+ L
Sbjct: 174 VTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNEL 233
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGH-LHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ GAN+NQ N + TPLH A + H C++ ++ ++G +NI ++ G +PLH+
Sbjct: 234 IDYGANVNQPNNNGFTPLHFAAASTHGALCLELLV----NNGADVNIQ--SKDGKSPLHM 287
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKT----AFDYAHNLRILQVLKSCTPNLFEYIHI 659
+ G ++ LI++G E + T A Y H L L +
Sbjct: 288 TAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHEL------------LINTLRT 335
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSD--TNDASKTIENLKLIERILRAISYGDVKLA 717
+ ++ K S P L N C + + K L A + G
Sbjct: 336 SGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVEC 395
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ + F DK L + C + +T T +VN D G TALHYAA
Sbjct: 396 IKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAA 455
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
+D N I A+ N + L T+ + LL N AN + D
Sbjct: 456 SDMDR--NKTILGNAHDNSEELERAREL---KEKEATLCLEFLLQNDANPSIRDKEGYNS 510
Query: 838 LHDASETGNIGAAKILL 854
+H A+ G+ ++LL
Sbjct: 511 IHYAAAYGHRQCLELLL 527
Score = 91.1 bits (216), Expect = 2e-17
Identities = 85/339 (25%), Positives = 155/339 (45%), Gaps = 17/339 (5%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
L+ ++N D + + LH A+ G ++ +L+ SGA +N K+ TPLH AV +
Sbjct: 2 LIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRS 61
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH 630
V+ +I +HS ++N +++ TPLH+A+ A ++I S ++ +
Sbjct: 62 EEAVQVLI---KHSA---DVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGG 115
Query: 631 KTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTN 690
+TA H+ + ++ L + +I + + K L + L + +
Sbjct: 116 RTAL---HHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLIN--H 170
Query: 691 DASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCK 750
A T ++ K + A S G + + +N+ I N+ H C
Sbjct: 171 GAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVE--IDEINVYGNTALHIAC-YNGQD 227
Query: 751 RKTESCTDF--DVNVCDSNGFTALHYAARYGLDEFC-NILIFNRANVNCRNKKAQTPLHL 807
D+ +VN ++NGFT LH+AA C +L+ N A+VN ++K ++PLH+
Sbjct: 228 AVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHM 287
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
A++ + + L+ NG I+ +D NTPLH A+ G+
Sbjct: 288 TAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGH 326
Score = 79.0 bits (186), Expect = 7e-14
Identities = 49/153 (32%), Positives = 74/153 (48%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +RD + T LHVA+ + E ++ + S +N +D +ALH+A+ GH ++ +L
Sbjct: 75 VNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLL 134
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GANIN + LH A GHL V +I H + C ++ G TPLH A
Sbjct: 135 LAKGANINAFDKKDRRALHWAAYMGHLDVVALLI---NHGA---EVTCKDKKGYTPLHAA 188
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G + + L+ G E N Y TA A
Sbjct: 189 ASNGQINVVKHLLNLGVEIDEINVYGNTALHIA 221
Score = 77.0 bits (181), Expect = 3e-13
Identities = 83/346 (23%), Positives = 147/346 (42%), Gaps = 15/346 (4%)
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
ML+H ++N + +K TPLH+A G ++ +I SG + +N + TPLH
Sbjct: 1 MLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLIL----SGAR--VNAKDNMWLTPLH 54
Query: 603 LASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSS 662
A E ++LI+H ++ + ++ +T A + ++ + P L ++++
Sbjct: 55 RAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIP-LLSSVNVSDR 113
Query: 663 EVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISY-GDVKLACFYM 721
+ + +++ NL L +A K R L +Y G + + +
Sbjct: 114 GGRTALHHAALNGHVEMVNLLLAKGANINAFD-----KKDRRALHWAAYMGHLDVVALLI 168
Query: 722 NIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLD 781
N + DK+ L Q K +++ + G TALH A G D
Sbjct: 169 N-HGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQD 227
Query: 782 EFCNILIFNRANVNCRNKKAQTPLHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHD 840
N LI ANVN N TPLH AA + + + + LL++NGA++N +PLH
Sbjct: 228 AVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHM 287
Query: 841 ASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+ G ++ L+ +I ++ T L VA H +I+ +
Sbjct: 288 TAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTL 333
Score = 66.9 bits (156), Expect = 3e-10
Identities = 88/400 (22%), Positives = 172/400 (43%), Gaps = 27/400 (6%)
Query: 504 KATI-VETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL---HSGANINQKNIDKN 559
+AT+ +E LL+ + + D +++HYA++ GH+ L +LL +SG + K+
Sbjct: 485 EATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKS 544
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
PLHLA NGH ++ ++ ++++ +E G T L LA+ G+ LI
Sbjct: 545 -PLHLAAYNGHHQALEVLLQSL------VDLDIRDEKGRTALDLAAFKGHTECVEALINP 597
Query: 620 GSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKL 679
G+ ++++ K +A ++ C L E I V + + P L +
Sbjct: 598 GASIFVKDNVTKRTPLHAS---VINGHTLCLRLLLE-IADNPEAVDVKDAKGQTPLMLAV 653
Query: 680 QNLTLKC-SDTNDASKTIENLKLI--ERILRAISYGDVKLACFYMNIDYSAFIAPDKEKS 736
+ S + ++ + ++ + R I G + C M ++ I +
Sbjct: 654 AYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEE--CVQMLLEQEVSILCKDSRG 711
Query: 737 NSLCHPLCECQYCKRKTE----SCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRA 792
+ H + +E + ++ D D+ G+T LH+A Y +E C ++ +
Sbjct: 712 RTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWAC-YNGNENCIEVLLEQK 770
Query: 793 NVNCRNKKAQTPLHLAAINNKTVVIRLLLD--NGANINAIDVARNTPLHDASETGNIGAA 850
TPLH A IN+ LLL + + ++ D TPL A+ ++
Sbjct: 771 CFRKFIGNPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVECL 830
Query: 851 KILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
++LL ++ + ++ + KTAL +A + +D++ N A
Sbjct: 831 QLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSA 870
Score = 55.2 bits (127), Expect = 1e-06
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
++ RD G T L A+ ++ LL + +NA D + +AL A+ G + +L
Sbjct: 807 VSCRDDKGRTPLRAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDIL 866
Query: 545 LHSG-ANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
++S A++ K+ D NTPLHLA + GH C I+
Sbjct: 867 VNSAQADLTVKDKDLNTPLHLACSKGHEKCALLIL 901
Score = 46.8 bits (106), Expect = 3e-04
Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLLEM--GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
T LH A I+ LL S ++ D + L A+ H L +LL A +
Sbjct: 781 TPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVECLQLLLRHSAPV 840
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + T L +A NG V ++ A+ ++ ++ NTPLHLA G+E
Sbjct: 841 NAVDNSGKTALMMAAENGQAGAVDILVNSAQ-----ADLTVKDKDLNTPLHLACSKGHEK 895
Query: 612 IARLLIEHGSEPSLQN 627
A L+++ + SL N
Sbjct: 896 CALLILDKIQDESLIN 911
Score = 46.0 bits (104), Expect = 6e-04
Identities = 30/115 (26%), Positives = 51/115 (44%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D C + LH AA + C L+ + ++ +K +T LH AA I+L
Sbjct: 339 DTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKL 398
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
L +GA+ + D TPLH A+ + + L++ ++ + +TAL A
Sbjct: 399 LQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYA 453
Score = 44.4 bits (100), Expect = 0.002
Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
V+ D G T L AA E +L+ + A VN + +T L +AA N + + +L
Sbjct: 807 VSCRDDKGRTPLRAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDIL 866
Query: 821 LDNG-ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLN 864
+++ A++ D NTPLH A G+ A ++L D +L+N
Sbjct: 867 VNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQDESLIN 911
Score = 37.5 bits (83), Expect = 0.21
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFN-RANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN D++G TAL AA G +IL+ + +A++ ++K TPLHLA L
Sbjct: 840 VNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALL 899
Query: 820 LLDNGANINAIDVARN 835
+LD + + I+ N
Sbjct: 900 ILDKIQDESLINEKNN 915
>BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 105 bits (251), Expect = 9e-22
Identities = 102/411 (24%), Positives = 182/411 (44%), Gaps = 31/411 (7%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH A+ G A I+E L+ G+ +NA D + LH A + + + +LL
Sbjct: 70 QDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKH 129
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A++N ++ + TPLH+A N + C +A++ N+N ++ +G T LH A+
Sbjct: 130 SADVNARDKNWQTPLHIAAANKAVKCAEALVPLLS------NVNVSDRAGRTALHHAAFS 183
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKI 667
G+ + +LL+ G+ + + + A +A + ++V+K + S ++
Sbjct: 184 GHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVK-----------LLVSHGAEV 232
Query: 668 SCESEKP-TSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF-----YM 721
+C+ +K T L S K + +L + A + +AC+ +
Sbjct: 233 TCKDKKSYTPLH----AAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 288
Query: 722 N--IDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESC--TDFDVNVCDSNGFTALHYAAR 777
N ID A + EK + H + E DVN+ +G T LH A
Sbjct: 289 NELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTAL 348
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
+G +I + A ++C +K TPLH+AA ++I L+ +GA+ + P
Sbjct: 349 HGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFP 408
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDN 888
LH A+ +G + LLS DI + +T L A +L ++L+ N
Sbjct: 409 LHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLN 459
Score = 103 bits (247), Expect = 3e-21
Identities = 110/424 (25%), Positives = 185/424 (43%), Gaps = 38/424 (8%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T +D T LH A+ G ++V+ LL++G ++N + + LH A G V+ L
Sbjct: 232 VTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNEL 291
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGH-LHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ GA +NQKN TPLH A + H C++ ++ G ++N ++ G TPLH+
Sbjct: 292 IDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLV------GNGADVNMKSKDGKTPLHM 345
Query: 604 ASKWGYEGIARLLIEHGS----EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH- 658
+ G ++ +I+ G+ E N+ A Y H L I ++ S IH
Sbjct: 346 TALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHG 405
Query: 659 ITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLAC 718
+ + +S S+ KL + +D +T L A + G L C
Sbjct: 406 MFPLHLAALSGFSD--CCRKLLSSGFDIDTPDDFGRT---------CLHAAAAGG-NLEC 453
Query: 719 FYMNIDYSA-FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ ++ A F DK + L + C Y + VN D G T LHYAA
Sbjct: 454 LNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAAT 513
Query: 778 YGLDEFC-NILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL-----LDNGANINAID 831
D C L+ N AN R+K+ +H +A + ++L+ LD + D
Sbjct: 514 SDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTD 573
Query: 832 V-------ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
+ A +PLH A+ G+ A ++L+ D+ + N++ +T L +A K H+ +D
Sbjct: 574 MLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVD 633
Query: 885 LIDN 888
++ N
Sbjct: 634 VLIN 637
Score = 85.4 bits (202), Expect = 8e-16
Identities = 89/386 (23%), Positives = 169/386 (43%), Gaps = 29/386 (7%)
Query: 485 MTSRDSHGLTALH--VASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
+ ++ G T LH AS HG A +E L+ G+++N + + LH + G +
Sbjct: 298 VNQKNEKGFTPLHFAAASTHG-ALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQ 356
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
++ SGA I+ ++ + NTPLH+A GH + +I + ++ G PLH
Sbjct: 357 TIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR------GIHGMFPLH 410
Query: 603 LASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAH---NLRILQVLKSCTPNLFEY--- 656
LA+ G+ R L+ G + + + +T A NL L +L + + +
Sbjct: 411 LAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKF 470
Query: 657 ----IHITSSEVKKISCESEKPTSLKLQNLTLK-CSDTNDASKTIENLKLIERILRAISY 711
+H ++ + + + +L + C+ + A+ + + K +E +LR +
Sbjct: 471 GRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDAN 530
Query: 712 GDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLC--ECQYCKRKTESCTDFDVNVCDSNGF 769
++ Y + YSA + LC L E S TD + +
Sbjct: 531 PGIRDKQGYNAVHYSAAYG------HRLCLQLIASETPLDVLMETSGTDMLSDSDNRATI 584
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
+ LH AA +G + +L+ + +++ RN +TPL LAA + +L++ GA+I
Sbjct: 585 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILV 644
Query: 830 ID-VARNTPLHDASETGNIGAAKILL 854
D + + TP+H A+ G+ ++L+
Sbjct: 645 KDYILKRTPIHAAATNGHSECLRLLI 670
Score = 83.0 bits (196), Expect = 4e-15
Identities = 86/351 (24%), Positives = 156/351 (44%), Gaps = 17/351 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A +G V L+ ++N D + + LH A+ G ++ +L+ SGA +N K+
Sbjct: 48 AIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKW 107
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH AV + V+ ++ +HS ++N +++ TPLH+A+ A L+
Sbjct: 108 LTPLHRAVASCSEEAVQVLL---KHSA---DVNARDKNWQTPLHIAAANKAVKCAEALVP 161
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLK 678
S ++ + +TA +A +++K L +I + + K
Sbjct: 162 LLSNVNVSDRAGRTALHHAAFSGHGEMVKLL---LSRGANINAFDKKDRRAIHWAAYMGH 218
Query: 679 LQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNS 738
++ + L S + A T ++ K + A S G + + + +D + N+
Sbjct: 219 IEVVKLLVS--HGAEVTCKDKKSYTPLHAAASSGMISVVKYL--LDLGVDMNEPNAYGNT 274
Query: 739 LCHPLC--ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFC-NILIFNRANVN 795
H C + C VN + GFT LH+AA C +L+ N A+VN
Sbjct: 275 PLHVACYNGQDVVVNELIDCGAI-VNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVN 333
Query: 796 CRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
++K +TPLH+ A++ + + ++ +GA I+ D NTPLH A+ G+
Sbjct: 334 MKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGH 384
Score = 78.2 bits (184), Expect = 1e-13
Identities = 44/153 (28%), Positives = 76/153 (49%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +RD + T LH+A+ + E L+ + S +N +D +ALH+A+ GH ++ +L
Sbjct: 133 VNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLL 192
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GANIN + +H A GH+ VK ++ H + C ++ TPLH A
Sbjct: 193 LSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLV---SHGA---EVTCKDKKSYTPLHAA 246
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G + + L++ G + + N+Y T A
Sbjct: 247 ASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVA 279
Score = 72.5 bits (170), Expect = 6e-12
Identities = 47/143 (32%), Positives = 71/143 (49%), Gaps = 6/143 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D N T LH AA + L+ +NVN ++ +T LH AA + +++L
Sbjct: 132 DVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKL 191
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL GANINA D +H A+ G+I K+L+S+ ++T + T L A
Sbjct: 192 LLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM 251
Query: 880 LTIID-LID-----NYANKYANT 896
++++ L+D N N Y NT
Sbjct: 252 ISVVKYLLDLGVDMNEPNAYGNT 274
Score = 68.1 bits (159), Expect = 1e-10
Identities = 45/149 (30%), Positives = 79/149 (53%), Gaps = 10/149 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATD-LNECSALHYASSRGHQNVLLMLLH 546
R+S G T L +A+ G V+ L+ G+ I D + + + +H A++ GH L +L+
Sbjct: 612 RNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIG 671
Query: 547 SGANINQKNI-DKN--TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ N +I D N TPL L+V NGH CV +++ + N++ ++ G T LH
Sbjct: 672 NAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLL------NKGANVDAKDKWGRTALHR 725
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKT 632
+ G+E L++HG++ L++S +T
Sbjct: 726 GAVTGHEECVDALLQHGAKCLLRDSRGRT 754
Score = 66.5 bits (155), Expect = 4e-10
Identities = 80/361 (22%), Positives = 152/361 (42%), Gaps = 15/361 (4%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A G + + L+ ++N ++ +K TPLH A G ++ +I SG +
Sbjct: 44 SLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLIL----SGAR 99
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+N + TPLH A E ++L++H ++ + ++ +T A + ++ +
Sbjct: 100 --VNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAE 157
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
+ P L ++++ + + ++ L L + A+ + K I
Sbjct: 158 ALVP-LLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL----SRGANINAFDKKDRRAIHW 212
Query: 708 AISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCEC-QYCKRKTESCTDFDVNVCDS 766
A G +++ + + + A + +KS + H K D+N ++
Sbjct: 213 AAYMGHIEVV--KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNA 270
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAIN-NKTVVIRLLLDNGA 825
G T LH A G D N LI A VN +N+K TPLH AA + + + + LL+ NGA
Sbjct: 271 YGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGA 330
Query: 826 NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDL 885
++N TPLH + G ++ ++ I + T L +A H +I+
Sbjct: 331 DVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINT 390
Query: 886 I 886
+
Sbjct: 391 L 391
Score = 65.7 bits (153), Expect = 7e-10
Identities = 39/142 (27%), Positives = 76/142 (53%), Gaps = 4/142 (2%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
++ LH+A+ HG +E L++ +++ + + + L A+ +GH + +L++ GA+I
Sbjct: 584 ISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 643
Query: 553 QKN-IDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
K+ I K TP+H A NGH C++ +I AE ++ + +G TPL L+ G+
Sbjct: 644 VKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTD 700
Query: 612 IARLLIEHGSEPSLQNSYHKTA 633
L+ G+ ++ + +TA
Sbjct: 701 CVYSLLNKGANVDAKDKWGRTA 722
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/163 (26%), Positives = 78/163 (47%), Gaps = 6/163 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++DS LT LH A V+ LL+ +++NA D N + LH A++ L
Sbjct: 100 VNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEAL 159
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +N+N + T LH A +GH VK ++ R NIN ++ +H A
Sbjct: 160 VPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL------SRGANINAFDKKDRRAIHWA 213
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ G+ + +LL+ HG+E + ++ T A + ++ V+K
Sbjct: 214 AYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVK 256
Score = 56.4 bits (130), Expect = 4e-07
Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 9/128 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDL---NECSALHYASSRGHQNVLLMLLHSGAN 550
T +H A+ +G + + L+ NA D+ N + L + GH + + LL+ GAN
Sbjct: 652 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 711
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++ K+ T LH GH CV A++ +H + + + G TP+HL++ G+
Sbjct: 712 VDAKDKWGRTALHRGAVTGHEECVDALL---QHGAKCL---LRDSRGRTPIHLSAACGHI 765
Query: 611 GIARLLIE 618
G+ L++
Sbjct: 766 GVLGALLQ 773
Score = 54.8 bits (126), Expect = 1e-06
Identities = 46/148 (31%), Positives = 71/148 (47%), Gaps = 18/148 (12%)
Query: 488 RDSHGLTALHVASIHGKATIV-----ETLLEMGSEINATDL-----NEC--SALHYASSR 535
RD G A+H ++ +G + ET L++ E + TD+ N S LH A+
Sbjct: 534 RDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYH 593
Query: 536 GHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANE 595
GH L +L+ S +++ +N TPL LA GH+ CV +I + G I +
Sbjct: 594 GHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLI----NQGASILVK-DYI 648
Query: 596 SGNTPLHLASKWGYEGIARLLIEHGSEP 623
TP+H A+ G+ RLLI + +EP
Sbjct: 649 LKRTPIHAAATNGHSECLRLLIGN-AEP 675
Score = 53.2 bits (122), Expect = 4e-06
Identities = 38/130 (29%), Positives = 65/130 (50%), Gaps = 4/130 (3%)
Query: 770 TALHYAARYGLDEFCNILIFN---RANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
T +H AA G E +LI N + V+ ++ QTPL L+ +N T + LL+ GAN
Sbjct: 652 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 711
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-L 885
++A D T LH + TG+ LL + L ++ +T + ++ H+ ++ L
Sbjct: 712 VDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGAL 771
Query: 886 IDNYANKYAN 895
+ + A+ AN
Sbjct: 772 LQSAASMDAN 781
Score = 51.6 bits (118), Expect = 1e-05
Identities = 28/94 (29%), Positives = 50/94 (53%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D +G T L ++ ++G V +LL G+ ++A D +ALH + GH+ + LL
Sbjct: 682 QDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQH 741
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFA 581
GA ++ TP+HL+ GH+ + A++ A
Sbjct: 742 GAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSA 775
Score = 47.6 bits (108), Expect = 2e-04
Identities = 29/94 (30%), Positives = 45/94 (47%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
V++ D NG T L + G + L+ ANV+ ++K +T LH A+ + L
Sbjct: 679 VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDAL 738
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L +GA D TP+H ++ G+IG LL
Sbjct: 739 LQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALL 772
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/137 (27%), Positives = 65/137 (47%), Gaps = 4/137 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNK-KAQTPLHLAAINNKTVVIR 818
D++V +S+G T L AA G E ++LI A++ ++ +TP+H AA N + +R
Sbjct: 608 DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLR 667
Query: 819 LLLDNGANINAIDVA---RNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
LL+ N NA+D+ TPL + G+ LL+ ++ + +TAL
Sbjct: 668 LLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGA 727
Query: 876 DKVHLTIIDLIDNYANK 892
H +D + + K
Sbjct: 728 VTGHEECVDALLQHGAK 744
Score = 39.5 bits (88), Expect = 0.052
Identities = 23/70 (32%), Positives = 39/70 (55%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ D G TALH A G +E + L+ + A R+ + +TP+HL+A V+
Sbjct: 711 NVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 770
Query: 820 LLDNGANINA 829
LL + A+++A
Sbjct: 771 LLQSAASMDA 780
>BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein.
Length = 782
Score = 105 bits (251), Expect = 9e-22
Identities = 102/411 (24%), Positives = 182/411 (44%), Gaps = 31/411 (7%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH A+ G A I+E L+ G+ +NA D + LH A + + + +LL
Sbjct: 67 QDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKH 126
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A++N ++ + TPLH+A N + C +A++ N+N ++ +G T LH A+
Sbjct: 127 SADVNARDKNWQTPLHIAAANKAVKCAEALVPLLS------NVNVSDRAGRTALHHAAFS 180
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKI 667
G+ + +LL+ G+ + + + A +A + ++V+K + S ++
Sbjct: 181 GHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVK-----------LLVSHGAEV 229
Query: 668 SCESEKP-TSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF-----YM 721
+C+ +K T L S K + +L + A + +AC+ +
Sbjct: 230 TCKDKKSYTPLH----AAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 285
Query: 722 N--IDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESC--TDFDVNVCDSNGFTALHYAAR 777
N ID A + EK + H + E DVN+ +G T LH A
Sbjct: 286 NELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTAL 345
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
+G +I + A ++C +K TPLH+AA ++I L+ +GA+ + P
Sbjct: 346 HGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFP 405
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDN 888
LH A+ +G + LLS DI + +T L A +L ++L+ N
Sbjct: 406 LHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLN 456
Score = 103 bits (247), Expect = 3e-21
Identities = 110/424 (25%), Positives = 185/424 (43%), Gaps = 38/424 (8%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T +D T LH A+ G ++V+ LL++G ++N + + LH A G V+ L
Sbjct: 229 VTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNEL 288
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGH-LHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ GA +NQKN TPLH A + H C++ ++ G ++N ++ G TPLH+
Sbjct: 289 IDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLV------GNGADVNMKSKDGKTPLHM 342
Query: 604 ASKWGYEGIARLLIEHGS----EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH- 658
+ G ++ +I+ G+ E N+ A Y H L I ++ S IH
Sbjct: 343 TALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHG 402
Query: 659 ITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLAC 718
+ + +S S+ KL + +D +T L A + G L C
Sbjct: 403 MFPLHLAALSGFSD--CCRKLLSSGFDIDTPDDFGRT---------CLHAAAAGG-NLEC 450
Query: 719 FYMNIDYSA-FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ ++ A F DK + L + C Y + VN D G T LHYAA
Sbjct: 451 LNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAAT 510
Query: 778 YGLDEFC-NILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL-----LDNGANINAID 831
D C L+ N AN R+K+ +H +A + ++L+ LD + D
Sbjct: 511 SDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTD 570
Query: 832 V-------ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
+ A +PLH A+ G+ A ++L+ D+ + N++ +T L +A K H+ +D
Sbjct: 571 MLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVD 630
Query: 885 LIDN 888
++ N
Sbjct: 631 VLIN 634
Score = 85.4 bits (202), Expect = 8e-16
Identities = 89/386 (23%), Positives = 169/386 (43%), Gaps = 29/386 (7%)
Query: 485 MTSRDSHGLTALH--VASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
+ ++ G T LH AS HG A +E L+ G+++N + + LH + G +
Sbjct: 295 VNQKNEKGFTPLHFAAASTHG-ALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQ 353
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
++ SGA I+ ++ + NTPLH+A GH + +I + ++ G PLH
Sbjct: 354 TIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR------GIHGMFPLH 407
Query: 603 LASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAH---NLRILQVLKSCTPNLFEY--- 656
LA+ G+ R L+ G + + + +T A NL L +L + + +
Sbjct: 408 LAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKF 467
Query: 657 ----IHITSSEVKKISCESEKPTSLKLQNLTLK-CSDTNDASKTIENLKLIERILRAISY 711
+H ++ + + + +L + C+ + A+ + + K +E +LR +
Sbjct: 468 GRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDAN 527
Query: 712 GDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLC--ECQYCKRKTESCTDFDVNVCDSNGF 769
++ Y + YSA + LC L E S TD + +
Sbjct: 528 PGIRDKQGYNAVHYSAAYG------HRLCLQLIASETPLDVLMETSGTDMLSDSDNRATI 581
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
+ LH AA +G + +L+ + +++ RN +TPL LAA + +L++ GA+I
Sbjct: 582 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILV 641
Query: 830 ID-VARNTPLHDASETGNIGAAKILL 854
D + + TP+H A+ G+ ++L+
Sbjct: 642 KDYILKRTPIHAAATNGHSECLRLLI 667
Score = 84.2 bits (199), Expect = 2e-15
Identities = 88/357 (24%), Positives = 159/357 (44%), Gaps = 17/357 (4%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
L +L A +G V L+ ++N D + + LH A+ G ++ +L+ SGA +N
Sbjct: 39 LPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVN 98
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
K+ TPLH AV + V+ ++ +HS ++N +++ TPLH+A+
Sbjct: 99 AKDSKWLTPLHRAVASCSEEAVQVLL---KHSA---DVNARDKNWQTPLHIAAANKAVKC 152
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESE 672
A L+ S ++ + +TA +A +++K L +I + + K
Sbjct: 153 AEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLL---LSRGANINAFDKKDRRAIHW 209
Query: 673 KPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPD 732
++ + L S + A T ++ K + A S G + + + +D +
Sbjct: 210 AAYMGHIEVVKLLVS--HGAEVTCKDKKSYTPLHAAASSGMISVVKYL--LDLGVDMNEP 265
Query: 733 KEKSNSLCHPLC--ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFC-NILIF 789
N+ H C + C VN + GFT LH+AA C +L+
Sbjct: 266 NAYGNTPLHVACYNGQDVVVNELIDCGAI-VNQKNEKGFTPLHFAAASTHGALCLELLVG 324
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
N A+VN ++K +TPLH+ A++ + + ++ +GA I+ D NTPLH A+ G+
Sbjct: 325 NGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGH 381
Score = 78.2 bits (184), Expect = 1e-13
Identities = 44/153 (28%), Positives = 76/153 (49%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +RD + T LH+A+ + E L+ + S +N +D +ALH+A+ GH ++ +L
Sbjct: 130 VNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLL 189
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GANIN + +H A GH+ VK ++ H + C ++ TPLH A
Sbjct: 190 LSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLV---SHGA---EVTCKDKKSYTPLHAA 243
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G + + L++ G + + N+Y T A
Sbjct: 244 ASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVA 276
Score = 72.5 bits (170), Expect = 6e-12
Identities = 47/143 (32%), Positives = 71/143 (49%), Gaps = 6/143 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D N T LH AA + L+ +NVN ++ +T LH AA + +++L
Sbjct: 129 DVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKL 188
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL GANINA D +H A+ G+I K+L+S+ ++T + T L A
Sbjct: 189 LLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM 248
Query: 880 LTIID-LID-----NYANKYANT 896
++++ L+D N N Y NT
Sbjct: 249 ISVVKYLLDLGVDMNEPNAYGNT 271
Score = 68.1 bits (159), Expect = 1e-10
Identities = 45/149 (30%), Positives = 79/149 (53%), Gaps = 10/149 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATD-LNECSALHYASSRGHQNVLLMLLH 546
R+S G T L +A+ G V+ L+ G+ I D + + + +H A++ GH L +L+
Sbjct: 609 RNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIG 668
Query: 547 SGANINQKNI-DKN--TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ N +I D N TPL L+V NGH CV +++ + N++ ++ G T LH
Sbjct: 669 NAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLL------NKGANVDAKDKWGRTALHR 722
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKT 632
+ G+E L++HG++ L++S +T
Sbjct: 723 GAVTGHEECVDALLQHGAKCLLRDSRGRT 751
Score = 67.3 bits (157), Expect = 2e-10
Identities = 81/365 (22%), Positives = 153/365 (41%), Gaps = 15/365 (4%)
Query: 524 NECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
N +L A G + + L+ ++N ++ +K TPLH A G ++ +I
Sbjct: 37 NVLPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLIL---- 92
Query: 584 SGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRIL 643
SG + +N + TPLH A E ++L++H ++ + ++ +T A + +
Sbjct: 93 SGAR--VNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAV 150
Query: 644 QVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIE 703
+ ++ P L ++++ + + ++ L L + A+ + K
Sbjct: 151 KCAEALVP-LLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL----SRGANINAFDKKDRR 205
Query: 704 RILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCEC-QYCKRKTESCTDFDVN 762
I A G +++ + + + A + +KS + H K D+N
Sbjct: 206 AIHWAAYMGHIEVV--KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMN 263
Query: 763 VCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAIN-NKTVVIRLLL 821
++ G T LH A G D N LI A VN +N+K TPLH AA + + + + LL+
Sbjct: 264 EPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLV 323
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
NGA++N TPLH + G ++ ++ I + T L +A H
Sbjct: 324 GNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHEL 383
Query: 882 IIDLI 886
+I+ +
Sbjct: 384 LINTL 388
Score = 65.7 bits (153), Expect = 7e-10
Identities = 39/142 (27%), Positives = 76/142 (53%), Gaps = 4/142 (2%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
++ LH+A+ HG +E L++ +++ + + + L A+ +GH + +L++ GA+I
Sbjct: 581 ISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 640
Query: 553 QKN-IDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
K+ I K TP+H A NGH C++ +I AE ++ + +G TPL L+ G+
Sbjct: 641 VKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTD 697
Query: 612 IARLLIEHGSEPSLQNSYHKTA 633
L+ G+ ++ + +TA
Sbjct: 698 CVYSLLNKGANVDAKDKWGRTA 719
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/163 (26%), Positives = 78/163 (47%), Gaps = 6/163 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++DS LT LH A V+ LL+ +++NA D N + LH A++ L
Sbjct: 97 VNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEAL 156
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +N+N + T LH A +GH VK ++ R NIN ++ +H A
Sbjct: 157 VPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL------SRGANINAFDKKDRRAIHWA 210
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ G+ + +LL+ HG+E + ++ T A + ++ V+K
Sbjct: 211 AYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVK 253
Score = 56.4 bits (130), Expect = 4e-07
Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 9/128 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDL---NECSALHYASSRGHQNVLLMLLHSGAN 550
T +H A+ +G + + L+ NA D+ N + L + GH + + LL+ GAN
Sbjct: 649 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 708
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++ K+ T LH GH CV A++ +H + + + G TP+HL++ G+
Sbjct: 709 VDAKDKWGRTALHRGAVTGHEECVDALL---QHGAKCL---LRDSRGRTPIHLSAACGHI 762
Query: 611 GIARLLIE 618
G+ L++
Sbjct: 763 GVLGALLQ 770
Score = 54.8 bits (126), Expect = 1e-06
Identities = 46/148 (31%), Positives = 71/148 (47%), Gaps = 18/148 (12%)
Query: 488 RDSHGLTALHVASIHGKATIV-----ETLLEMGSEINATDL-----NEC--SALHYASSR 535
RD G A+H ++ +G + ET L++ E + TD+ N S LH A+
Sbjct: 531 RDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYH 590
Query: 536 GHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANE 595
GH L +L+ S +++ +N TPL LA GH+ CV +I + G I +
Sbjct: 591 GHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLI----NQGASILVK-DYI 645
Query: 596 SGNTPLHLASKWGYEGIARLLIEHGSEP 623
TP+H A+ G+ RLLI + +EP
Sbjct: 646 LKRTPIHAAATNGHSECLRLLIGN-AEP 672
Score = 53.2 bits (122), Expect = 4e-06
Identities = 38/130 (29%), Positives = 65/130 (50%), Gaps = 4/130 (3%)
Query: 770 TALHYAARYGLDEFCNILIFN---RANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
T +H AA G E +LI N + V+ ++ QTPL L+ +N T + LL+ GAN
Sbjct: 649 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 708
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-L 885
++A D T LH + TG+ LL + L ++ +T + ++ H+ ++ L
Sbjct: 709 VDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGAL 768
Query: 886 IDNYANKYAN 895
+ + A+ AN
Sbjct: 769 LQSAASMDAN 778
Score = 51.6 bits (118), Expect = 1e-05
Identities = 28/94 (29%), Positives = 50/94 (53%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D +G T L ++ ++G V +LL G+ ++A D +ALH + GH+ + LL
Sbjct: 679 QDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQH 738
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFA 581
GA ++ TP+HL+ GH+ + A++ A
Sbjct: 739 GAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSA 772
Score = 47.6 bits (108), Expect = 2e-04
Identities = 29/94 (30%), Positives = 45/94 (47%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
V++ D NG T L + G + L+ ANV+ ++K +T LH A+ + L
Sbjct: 676 VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDAL 735
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L +GA D TP+H ++ G+IG LL
Sbjct: 736 LQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALL 769
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/137 (27%), Positives = 65/137 (47%), Gaps = 4/137 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNK-KAQTPLHLAAINNKTVVIR 818
D++V +S+G T L AA G E ++LI A++ ++ +TP+H AA N + +R
Sbjct: 605 DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLR 664
Query: 819 LLLDNGANINAIDVA---RNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
LL+ N NA+D+ TPL + G+ LL+ ++ + +TAL
Sbjct: 665 LLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGA 724
Query: 876 DKVHLTIIDLIDNYANK 892
H +D + + K
Sbjct: 725 VTGHEECVDALLQHGAK 741
Score = 39.5 bits (88), Expect = 0.052
Identities = 23/70 (32%), Positives = 39/70 (55%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ D G TALH A G +E + L+ + A R+ + +TP+HL+A V+
Sbjct: 708 NVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 767
Query: 820 LLDNGANINA 829
LL + A+++A
Sbjct: 768 LLQSAASMDA 777
>BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 105 bits (251), Expect = 9e-22
Identities = 102/411 (24%), Positives = 182/411 (44%), Gaps = 31/411 (7%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH A+ G A I+E L+ G+ +NA D + LH A + + + +LL
Sbjct: 70 QDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKH 129
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A++N ++ + TPLH+A N + C +A++ N+N ++ +G T LH A+
Sbjct: 130 SADVNARDKNWQTPLHIAAANKAVKCAEALVPLLS------NVNVSDRAGRTALHHAAFS 183
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKI 667
G+ + +LL+ G+ + + + A +A + ++V+K + S ++
Sbjct: 184 GHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVK-----------LLVSHGAEV 232
Query: 668 SCESEKP-TSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF-----YM 721
+C+ +K T L S K + +L + A + +AC+ +
Sbjct: 233 TCKDKKSYTPLH----AAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 288
Query: 722 N--IDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESC--TDFDVNVCDSNGFTALHYAAR 777
N ID A + EK + H + E DVN+ +G T LH A
Sbjct: 289 NELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTAL 348
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
+G +I + A ++C +K TPLH+AA ++I L+ +GA+ + P
Sbjct: 349 HGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFP 408
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDN 888
LH A+ +G + LLS DI + +T L A +L ++L+ N
Sbjct: 409 LHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLN 459
Score = 103 bits (247), Expect = 3e-21
Identities = 110/424 (25%), Positives = 185/424 (43%), Gaps = 38/424 (8%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T +D T LH A+ G ++V+ LL++G ++N + + LH A G V+ L
Sbjct: 232 VTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNEL 291
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGH-LHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ GA +NQKN TPLH A + H C++ ++ G ++N ++ G TPLH+
Sbjct: 292 IDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLV------GNGADVNMKSKDGKTPLHM 345
Query: 604 ASKWGYEGIARLLIEHGS----EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH- 658
+ G ++ +I+ G+ E N+ A Y H L I ++ S IH
Sbjct: 346 TALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHG 405
Query: 659 ITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLAC 718
+ + +S S+ KL + +D +T L A + G L C
Sbjct: 406 MFPLHLAALSGFSD--CCRKLLSSGFDIDTPDDFGRT---------CLHAAAAGG-NLEC 453
Query: 719 FYMNIDYSA-FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ ++ A F DK + L + C Y + VN D G T LHYAA
Sbjct: 454 LNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAAT 513
Query: 778 YGLDEFC-NILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL-----LDNGANINAID 831
D C L+ N AN R+K+ +H +A + ++L+ LD + D
Sbjct: 514 SDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTD 573
Query: 832 V-------ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
+ A +PLH A+ G+ A ++L+ D+ + N++ +T L +A K H+ +D
Sbjct: 574 MLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVD 633
Query: 885 LIDN 888
++ N
Sbjct: 634 VLIN 637
Score = 85.4 bits (202), Expect = 8e-16
Identities = 89/386 (23%), Positives = 169/386 (43%), Gaps = 29/386 (7%)
Query: 485 MTSRDSHGLTALH--VASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
+ ++ G T LH AS HG A +E L+ G+++N + + LH + G +
Sbjct: 298 VNQKNEKGFTPLHFAAASTHG-ALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQ 356
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
++ SGA I+ ++ + NTPLH+A GH + +I + ++ G PLH
Sbjct: 357 TIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR------GIHGMFPLH 410
Query: 603 LASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAH---NLRILQVLKSCTPNLFEY--- 656
LA+ G+ R L+ G + + + +T A NL L +L + + +
Sbjct: 411 LAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKF 470
Query: 657 ----IHITSSEVKKISCESEKPTSLKLQNLTLK-CSDTNDASKTIENLKLIERILRAISY 711
+H ++ + + + +L + C+ + A+ + + K +E +LR +
Sbjct: 471 GRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDAN 530
Query: 712 GDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLC--ECQYCKRKTESCTDFDVNVCDSNGF 769
++ Y + YSA + LC L E S TD + +
Sbjct: 531 PGIRDKQGYNAVHYSAAYG------HRLCLQLIASETPLDVLMETSGTDMLSDSDNRATI 584
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
+ LH AA +G + +L+ + +++ RN +TPL LAA + +L++ GA+I
Sbjct: 585 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILV 644
Query: 830 ID-VARNTPLHDASETGNIGAAKILL 854
D + + TP+H A+ G+ ++L+
Sbjct: 645 KDYILKRTPIHAAATNGHSECLRLLI 670
Score = 83.0 bits (196), Expect = 4e-15
Identities = 86/351 (24%), Positives = 156/351 (44%), Gaps = 17/351 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A +G V L+ ++N D + + LH A+ G ++ +L+ SGA +N K+
Sbjct: 48 AIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKW 107
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH AV + V+ ++ +HS ++N +++ TPLH+A+ A L+
Sbjct: 108 LTPLHRAVASCSEEAVQVLL---KHSA---DVNARDKNWQTPLHIAAANKAVKCAEALVP 161
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLK 678
S ++ + +TA +A +++K L +I + + K
Sbjct: 162 LLSNVNVSDRAGRTALHHAAFSGHGEMVKLL---LSRGANINAFDKKDRRAIHWAAYMGH 218
Query: 679 LQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNS 738
++ + L S + A T ++ K + A S G + + + +D + N+
Sbjct: 219 IEVVKLLVS--HGAEVTCKDKKSYTPLHAAASSGMISVVKYL--LDLGVDMNEPNAYGNT 274
Query: 739 LCHPLC--ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFC-NILIFNRANVN 795
H C + C VN + GFT LH+AA C +L+ N A+VN
Sbjct: 275 PLHVACYNGQDVVVNELIDCGAI-VNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVN 333
Query: 796 CRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
++K +TPLH+ A++ + + ++ +GA I+ D NTPLH A+ G+
Sbjct: 334 MKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGH 384
Score = 78.2 bits (184), Expect = 1e-13
Identities = 44/153 (28%), Positives = 76/153 (49%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +RD + T LH+A+ + E L+ + S +N +D +ALH+A+ GH ++ +L
Sbjct: 133 VNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLL 192
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GANIN + +H A GH+ VK ++ H + C ++ TPLH A
Sbjct: 193 LSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLV---SHGA---EVTCKDKKSYTPLHAA 246
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G + + L++ G + + N+Y T A
Sbjct: 247 ASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVA 279
Score = 72.5 bits (170), Expect = 6e-12
Identities = 47/143 (32%), Positives = 71/143 (49%), Gaps = 6/143 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D N T LH AA + L+ +NVN ++ +T LH AA + +++L
Sbjct: 132 DVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKL 191
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL GANINA D +H A+ G+I K+L+S+ ++T + T L A
Sbjct: 192 LLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM 251
Query: 880 LTIID-LID-----NYANKYANT 896
++++ L+D N N Y NT
Sbjct: 252 ISVVKYLLDLGVDMNEPNAYGNT 274
Score = 68.1 bits (159), Expect = 1e-10
Identities = 45/149 (30%), Positives = 79/149 (53%), Gaps = 10/149 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATD-LNECSALHYASSRGHQNVLLMLLH 546
R+S G T L +A+ G V+ L+ G+ I D + + + +H A++ GH L +L+
Sbjct: 612 RNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIG 671
Query: 547 SGANINQKNI-DKN--TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ N +I D N TPL L+V NGH CV +++ + N++ ++ G T LH
Sbjct: 672 NAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLL------NKGANVDAKDKWGRTALHR 725
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKT 632
+ G+E L++HG++ L++S +T
Sbjct: 726 GAVTGHEECVDALLQHGAKCLLRDSRGRT 754
Score = 66.5 bits (155), Expect = 4e-10
Identities = 80/361 (22%), Positives = 152/361 (42%), Gaps = 15/361 (4%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A G + + L+ ++N ++ +K TPLH A G ++ +I SG +
Sbjct: 44 SLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLIL----SGAR 99
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+N + TPLH A E ++L++H ++ + ++ +T A + ++ +
Sbjct: 100 --VNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAE 157
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
+ P L ++++ + + ++ L L + A+ + K I
Sbjct: 158 ALVP-LLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL----SRGANINAFDKKDRRAIHW 212
Query: 708 AISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCEC-QYCKRKTESCTDFDVNVCDS 766
A G +++ + + + A + +KS + H K D+N ++
Sbjct: 213 AAYMGHIEVV--KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNA 270
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAIN-NKTVVIRLLLDNGA 825
G T LH A G D N LI A VN +N+K TPLH AA + + + + LL+ NGA
Sbjct: 271 YGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGA 330
Query: 826 NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDL 885
++N TPLH + G ++ ++ I + T L +A H +I+
Sbjct: 331 DVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINT 390
Query: 886 I 886
+
Sbjct: 391 L 391
Score = 65.7 bits (153), Expect = 7e-10
Identities = 39/142 (27%), Positives = 76/142 (53%), Gaps = 4/142 (2%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
++ LH+A+ HG +E L++ +++ + + + L A+ +GH + +L++ GA+I
Sbjct: 584 ISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 643
Query: 553 QKN-IDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
K+ I K TP+H A NGH C++ +I AE ++ + +G TPL L+ G+
Sbjct: 644 VKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTD 700
Query: 612 IARLLIEHGSEPSLQNSYHKTA 633
L+ G+ ++ + +TA
Sbjct: 701 CVYSLLNKGANVDAKDKWGRTA 722
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/163 (26%), Positives = 78/163 (47%), Gaps = 6/163 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++DS LT LH A V+ LL+ +++NA D N + LH A++ L
Sbjct: 100 VNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEAL 159
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +N+N + T LH A +GH VK ++ R NIN ++ +H A
Sbjct: 160 VPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL------SRGANINAFDKKDRRAIHWA 213
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ G+ + +LL+ HG+E + ++ T A + ++ V+K
Sbjct: 214 AYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVK 256
Score = 56.4 bits (130), Expect = 4e-07
Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 9/128 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDL---NECSALHYASSRGHQNVLLMLLHSGAN 550
T +H A+ +G + + L+ NA D+ N + L + GH + + LL+ GAN
Sbjct: 652 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 711
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++ K+ T LH GH CV A++ +H + + + G TP+HL++ G+
Sbjct: 712 VDAKDKWGRTALHRGAVTGHEECVDALL---QHGAKCL---LRDSRGRTPIHLSAACGHI 765
Query: 611 GIARLLIE 618
G+ L++
Sbjct: 766 GVLGALLQ 773
Score = 54.8 bits (126), Expect = 1e-06
Identities = 46/148 (31%), Positives = 71/148 (47%), Gaps = 18/148 (12%)
Query: 488 RDSHGLTALHVASIHGKATIV-----ETLLEMGSEINATDL-----NEC--SALHYASSR 535
RD G A+H ++ +G + ET L++ E + TD+ N S LH A+
Sbjct: 534 RDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYH 593
Query: 536 GHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANE 595
GH L +L+ S +++ +N TPL LA GH+ CV +I + G I +
Sbjct: 594 GHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLI----NQGASILVK-DYI 648
Query: 596 SGNTPLHLASKWGYEGIARLLIEHGSEP 623
TP+H A+ G+ RLLI + +EP
Sbjct: 649 LKRTPIHAAATNGHSECLRLLIGN-AEP 675
Score = 53.2 bits (122), Expect = 4e-06
Identities = 38/130 (29%), Positives = 65/130 (50%), Gaps = 4/130 (3%)
Query: 770 TALHYAARYGLDEFCNILIFN---RANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
T +H AA G E +LI N + V+ ++ QTPL L+ +N T + LL+ GAN
Sbjct: 652 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 711
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-L 885
++A D T LH + TG+ LL + L ++ +T + ++ H+ ++ L
Sbjct: 712 VDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGAL 771
Query: 886 IDNYANKYAN 895
+ + A+ AN
Sbjct: 772 LQSAASMDAN 781
Score = 51.6 bits (118), Expect = 1e-05
Identities = 28/94 (29%), Positives = 50/94 (53%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D +G T L ++ ++G V +LL G+ ++A D +ALH + GH+ + LL
Sbjct: 682 QDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQH 741
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFA 581
GA ++ TP+HL+ GH+ + A++ A
Sbjct: 742 GAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSA 775
Score = 47.6 bits (108), Expect = 2e-04
Identities = 29/94 (30%), Positives = 45/94 (47%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
V++ D NG T L + G + L+ ANV+ ++K +T LH A+ + L
Sbjct: 679 VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDAL 738
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L +GA D TP+H ++ G+IG LL
Sbjct: 739 LQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALL 772
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/137 (27%), Positives = 65/137 (47%), Gaps = 4/137 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNK-KAQTPLHLAAINNKTVVIR 818
D++V +S+G T L AA G E ++LI A++ ++ +TP+H AA N + +R
Sbjct: 608 DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLR 667
Query: 819 LLLDNGANINAIDVA---RNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
LL+ N NA+D+ TPL + G+ LL+ ++ + +TAL
Sbjct: 668 LLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGA 727
Query: 876 DKVHLTIIDLIDNYANK 892
H +D + + K
Sbjct: 728 VTGHEECVDALLQHGAK 744
Score = 39.5 bits (88), Expect = 0.052
Identities = 23/70 (32%), Positives = 39/70 (55%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ D G TALH A G +E + L+ + A R+ + +TP+HL+A V+
Sbjct: 711 NVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 770
Query: 820 LLDNGANINA 829
LL + A+++A
Sbjct: 771 LLQSAASMDA 780
>AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens
cDNA FLJ44940 fis, clone BRAMY4000915, weakly similar
to Ankyrin 1. ).
Length = 687
Score = 105 bits (251), Expect = 9e-22
Identities = 102/411 (24%), Positives = 182/411 (44%), Gaps = 31/411 (7%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH A+ G A I+E L+ G+ +NA D + LH A + + + +LL
Sbjct: 70 QDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKH 129
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A++N ++ + TPLH+A N + C +A++ N+N ++ +G T LH A+
Sbjct: 130 SADVNARDKNWQTPLHIAAANKAVKCAEALVPLLS------NVNVSDRAGRTALHHAAFS 183
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKI 667
G+ + +LL+ G+ + + + A +A + ++V+K + S ++
Sbjct: 184 GHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVK-----------LLVSHGAEV 232
Query: 668 SCESEKP-TSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF-----YM 721
+C+ +K T L S K + +L + A + +AC+ +
Sbjct: 233 TCKDKKSYTPLH----AAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 288
Query: 722 N--IDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESC--TDFDVNVCDSNGFTALHYAAR 777
N ID A + EK + H + E DVN+ +G T LH A
Sbjct: 289 NELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTAL 348
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
+G +I + A ++C +K TPLH+AA ++I L+ +GA+ + P
Sbjct: 349 HGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFP 408
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDN 888
LH A+ +G + LLS DI + +T L A +L ++L+ N
Sbjct: 409 LHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLN 459
Score = 103 bits (247), Expect = 3e-21
Identities = 110/424 (25%), Positives = 185/424 (43%), Gaps = 38/424 (8%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T +D T LH A+ G ++V+ LL++G ++N + + LH A G V+ L
Sbjct: 232 VTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNEL 291
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGH-LHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ GA +NQKN TPLH A + H C++ ++ G ++N ++ G TPLH+
Sbjct: 292 IDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLV------GNGADVNMKSKDGKTPLHM 345
Query: 604 ASKWGYEGIARLLIEHGS----EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH- 658
+ G ++ +I+ G+ E N+ A Y H L I ++ S IH
Sbjct: 346 TALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHG 405
Query: 659 ITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLAC 718
+ + +S S+ KL + +D +T L A + G L C
Sbjct: 406 MFPLHLAALSGFSD--CCRKLLSSGFDIDTPDDFGRT---------CLHAAAAGG-NLEC 453
Query: 719 FYMNIDYSA-FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ ++ A F DK + L + C Y + VN D G T LHYAA
Sbjct: 454 LNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAAT 513
Query: 778 YGLDEFC-NILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL-----LDNGANINAID 831
D C L+ N AN R+K+ +H +A + ++L+ LD + D
Sbjct: 514 SDTDGKCLEYLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTD 573
Query: 832 V-------ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
+ A +PLH A+ G+ A ++L+ D+ + N++ +T L +A K H+ +D
Sbjct: 574 MLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVD 633
Query: 885 LIDN 888
++ N
Sbjct: 634 VLIN 637
Score = 85.8 bits (203), Expect = 6e-16
Identities = 90/386 (23%), Positives = 169/386 (43%), Gaps = 29/386 (7%)
Query: 485 MTSRDSHGLTALH--VASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
+ ++ G T LH AS HG A +E L+ G+++N + + LH + G +
Sbjct: 298 VNQKNEKGFTPLHFAAASTHG-ALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQ 356
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
++ SGA I+ ++ + NTPLH+A GH + +I + ++ G PLH
Sbjct: 357 TIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR------GIHGMFPLH 410
Query: 603 LASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAH---NLRILQVLKSCTPNLFEY--- 656
LA+ G+ R L+ G + + + +T A NL L +L + + +
Sbjct: 411 LAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKF 470
Query: 657 ----IHITSSEVKKISCESEKPTSLKLQNLTLK-CSDTNDASKTIENLKLIERILRAISY 711
+H ++ + + + +L + C+ + A+ + + K +E +LR +
Sbjct: 471 GRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDAN 530
Query: 712 GDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLC--ECQYCKRKTESCTDFDVNVCDSNGF 769
V+ Y + YSA + LC L E S TD + +
Sbjct: 531 PGVRDKQGYNAVHYSAAYG------HRLCLQLIASETPLDVLMETSGTDMLSDSDNRATI 584
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
+ LH AA +G + +L+ + +++ RN +TPL LAA + +L++ GA+I
Sbjct: 585 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILV 644
Query: 830 ID-VARNTPLHDASETGNIGAAKILL 854
D + + TP+H A+ G+ ++L+
Sbjct: 645 KDYILKRTPIHAAATNGHSECLRLLI 670
Score = 83.0 bits (196), Expect = 4e-15
Identities = 86/351 (24%), Positives = 156/351 (44%), Gaps = 17/351 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A +G V L+ ++N D + + LH A+ G ++ +L+ SGA +N K+
Sbjct: 48 AIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKW 107
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH AV + V+ ++ +HS ++N +++ TPLH+A+ A L+
Sbjct: 108 LTPLHRAVASCSEEAVQVLL---KHSA---DVNARDKNWQTPLHIAAANKAVKCAEALVP 161
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLK 678
S ++ + +TA +A +++K L +I + + K
Sbjct: 162 LLSNVNVSDRAGRTALHHAAFSGHGEMVKLL---LSRGANINAFDKKDRRAIHWAAYMGH 218
Query: 679 LQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNS 738
++ + L S + A T ++ K + A S G + + + +D + N+
Sbjct: 219 IEVVKLLVS--HGAEVTCKDKKSYTPLHAAASSGMISVVKYL--LDLGVDMNEPNAYGNT 274
Query: 739 LCHPLC--ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFC-NILIFNRANVN 795
H C + C VN + GFT LH+AA C +L+ N A+VN
Sbjct: 275 PLHVACYNGQDVVVNELIDCGAI-VNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVN 333
Query: 796 CRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
++K +TPLH+ A++ + + ++ +GA I+ D NTPLH A+ G+
Sbjct: 334 MKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGH 384
Score = 78.2 bits (184), Expect = 1e-13
Identities = 44/153 (28%), Positives = 76/153 (49%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +RD + T LH+A+ + E L+ + S +N +D +ALH+A+ GH ++ +L
Sbjct: 133 VNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLL 192
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GANIN + +H A GH+ VK ++ H + C ++ TPLH A
Sbjct: 193 LSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLV---SHGA---EVTCKDKKSYTPLHAA 246
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G + + L++ G + + N+Y T A
Sbjct: 247 ASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVA 279
Score = 72.5 bits (170), Expect = 6e-12
Identities = 47/143 (32%), Positives = 71/143 (49%), Gaps = 6/143 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D N T LH AA + L+ +NVN ++ +T LH AA + +++L
Sbjct: 132 DVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKL 191
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL GANINA D +H A+ G+I K+L+S+ ++T + T L A
Sbjct: 192 LLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM 251
Query: 880 LTIID-LID-----NYANKYANT 896
++++ L+D N N Y NT
Sbjct: 252 ISVVKYLLDLGVDMNEPNAYGNT 274
Score = 66.5 bits (155), Expect = 4e-10
Identities = 80/361 (22%), Positives = 152/361 (42%), Gaps = 15/361 (4%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A G + + L+ ++N ++ +K TPLH A G ++ +I SG +
Sbjct: 44 SLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLIL----SGAR 99
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+N + TPLH A E ++L++H ++ + ++ +T A + ++ +
Sbjct: 100 --VNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAE 157
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
+ P L ++++ + + ++ L L + A+ + K I
Sbjct: 158 ALVP-LLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL----SRGANINAFDKKDRRAIHW 212
Query: 708 AISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCEC-QYCKRKTESCTDFDVNVCDS 766
A G +++ + + + A + +KS + H K D+N ++
Sbjct: 213 AAYMGHIEVV--KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNA 270
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAIN-NKTVVIRLLLDNGA 825
G T LH A G D N LI A VN +N+K TPLH AA + + + + LL+ NGA
Sbjct: 271 YGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGA 330
Query: 826 NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDL 885
++N TPLH + G ++ ++ I + T L +A H +I+
Sbjct: 331 DVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINT 390
Query: 886 I 886
+
Sbjct: 391 L 391
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/163 (26%), Positives = 78/163 (47%), Gaps = 6/163 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++DS LT LH A V+ LL+ +++NA D N + LH A++ L
Sbjct: 100 VNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEAL 159
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +N+N + T LH A +GH VK ++ R NIN ++ +H A
Sbjct: 160 VPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL------SRGANINAFDKKDRRAIHWA 213
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ G+ + +LL+ HG+E + ++ T A + ++ V+K
Sbjct: 214 AYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVK 256
Score = 54.8 bits (126), Expect = 1e-06
Identities = 46/148 (31%), Positives = 71/148 (47%), Gaps = 18/148 (12%)
Query: 488 RDSHGLTALHVASIHGKATIV-----ETLLEMGSEINATDL-----NEC--SALHYASSR 535
RD G A+H ++ +G + ET L++ E + TD+ N S LH A+
Sbjct: 534 RDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYH 593
Query: 536 GHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANE 595
GH L +L+ S +++ +N TPL LA GH+ CV +I + G I +
Sbjct: 594 GHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLI----NQGASILVK-DYI 648
Query: 596 SGNTPLHLASKWGYEGIARLLIEHGSEP 623
TP+H A+ G+ RLLI + +EP
Sbjct: 649 LKRTPIHAAATNGHSECLRLLIGN-AEP 675
Score = 43.2 bits (97), Expect = 0.004
Identities = 26/74 (35%), Positives = 43/74 (58%), Gaps = 1/74 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNK-KAQTPLHLAAINNKTVVIR 818
D++V +S+G T L AA G E ++LI A++ ++ +TP+H AA N + +R
Sbjct: 608 DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLR 667
Query: 819 LLLDNGANINAIDV 832
LL+ N NA+D+
Sbjct: 668 LLIGNAEPQNAVDI 681
>AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein.
Length = 1059
Score = 105 bits (251), Expect = 9e-22
Identities = 102/411 (24%), Positives = 182/411 (44%), Gaps = 31/411 (7%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH A+ G A I+E L+ G+ +NA D + LH A + + + +LL
Sbjct: 43 QDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKH 102
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A++N ++ + TPLH+A N + C +A++ N+N ++ +G T LH A+
Sbjct: 103 SADVNARDKNWQTPLHIAAANKAVKCAEALVPLLS------NVNVSDRAGRTALHHAAFS 156
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKI 667
G+ + +LL+ G+ + + + A +A + ++V+K + S ++
Sbjct: 157 GHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVK-----------LLVSHGAEV 205
Query: 668 SCESEKP-TSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF-----YM 721
+C+ +K T L S K + +L + A + +AC+ +
Sbjct: 206 TCKDKKSYTPLH----AAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 261
Query: 722 N--IDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESC--TDFDVNVCDSNGFTALHYAAR 777
N ID A + EK + H + E DVN+ +G T LH A
Sbjct: 262 NELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTAL 321
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
+G +I + A ++C +K TPLH+AA ++I L+ +GA+ + P
Sbjct: 322 HGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFP 381
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDN 888
LH A+ +G + LLS DI + +T L A +L ++L+ N
Sbjct: 382 LHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLN 432
Score = 103 bits (247), Expect = 3e-21
Identities = 110/424 (25%), Positives = 185/424 (43%), Gaps = 38/424 (8%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T +D T LH A+ G ++V+ LL++G ++N + + LH A G V+ L
Sbjct: 205 VTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNEL 264
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGH-LHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ GA +NQKN TPLH A + H C++ ++ G ++N ++ G TPLH+
Sbjct: 265 IDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLV------GNGADVNMKSKDGKTPLHM 318
Query: 604 ASKWGYEGIARLLIEHGS----EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH- 658
+ G ++ +I+ G+ E N+ A Y H L I ++ S IH
Sbjct: 319 TALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHG 378
Query: 659 ITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLAC 718
+ + +S S+ KL + +D +T L A + G L C
Sbjct: 379 MFPLHLAALSGFSD--CCRKLLSSGFDIDTPDDFGRT---------CLHAAAAGG-NLEC 426
Query: 719 FYMNIDYSA-FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ ++ A F DK + L + C Y + VN D G T LHYAA
Sbjct: 427 LNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAAT 486
Query: 778 YGLDEFC-NILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL-----LDNGANINAID 831
D C L+ N AN R+K+ +H +A + ++L+ LD + D
Sbjct: 487 SDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTD 546
Query: 832 V-------ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
+ A +PLH A+ G+ A ++L+ D+ + N++ +T L +A K H+ +D
Sbjct: 547 MLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVD 606
Query: 885 LIDN 888
++ N
Sbjct: 607 VLIN 610
Score = 85.4 bits (202), Expect = 8e-16
Identities = 89/386 (23%), Positives = 169/386 (43%), Gaps = 29/386 (7%)
Query: 485 MTSRDSHGLTALH--VASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
+ ++ G T LH AS HG A +E L+ G+++N + + LH + G +
Sbjct: 271 VNQKNEKGFTPLHFAAASTHG-ALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQ 329
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
++ SGA I+ ++ + NTPLH+A GH + +I + ++ G PLH
Sbjct: 330 TIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR------GIHGMFPLH 383
Query: 603 LASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAH---NLRILQVLKSCTPNLFEY--- 656
LA+ G+ R L+ G + + + +T A NL L +L + + +
Sbjct: 384 LAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKF 443
Query: 657 ----IHITSSEVKKISCESEKPTSLKLQNLTLK-CSDTNDASKTIENLKLIERILRAISY 711
+H ++ + + + +L + C+ + A+ + + K +E +LR +
Sbjct: 444 GRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDAN 503
Query: 712 GDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLC--ECQYCKRKTESCTDFDVNVCDSNGF 769
++ Y + YSA + LC L E S TD + +
Sbjct: 504 PGIRDKQGYNAVHYSAAYG------HRLCLQLIASETPLDVLMETSGTDMLSDSDNRATI 557
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
+ LH AA +G + +L+ + +++ RN +TPL LAA + +L++ GA+I
Sbjct: 558 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILV 617
Query: 830 ID-VARNTPLHDASETGNIGAAKILL 854
D + + TP+H A+ G+ ++L+
Sbjct: 618 KDYILKRTPIHAAATNGHSECLRLLI 643
Score = 83.0 bits (196), Expect = 4e-15
Identities = 86/351 (24%), Positives = 156/351 (44%), Gaps = 17/351 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A +G V L+ ++N D + + LH A+ G ++ +L+ SGA +N K+
Sbjct: 21 AIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKW 80
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH AV + V+ ++ +HS ++N +++ TPLH+A+ A L+
Sbjct: 81 LTPLHRAVASCSEEAVQVLL---KHSA---DVNARDKNWQTPLHIAAANKAVKCAEALVP 134
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLK 678
S ++ + +TA +A +++K L +I + + K
Sbjct: 135 LLSNVNVSDRAGRTALHHAAFSGHGEMVKLL---LSRGANINAFDKKDRRAIHWAAYMGH 191
Query: 679 LQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNS 738
++ + L S + A T ++ K + A S G + + + +D + N+
Sbjct: 192 IEVVKLLVS--HGAEVTCKDKKSYTPLHAAASSGMISVVKYL--LDLGVDMNEPNAYGNT 247
Query: 739 LCHPLC--ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFC-NILIFNRANVN 795
H C + C VN + GFT LH+AA C +L+ N A+VN
Sbjct: 248 PLHVACYNGQDVVVNELIDCGAI-VNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVN 306
Query: 796 CRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
++K +TPLH+ A++ + + ++ +GA I+ D NTPLH A+ G+
Sbjct: 307 MKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGH 357
Score = 78.2 bits (184), Expect = 1e-13
Identities = 44/153 (28%), Positives = 76/153 (49%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +RD + T LH+A+ + E L+ + S +N +D +ALH+A+ GH ++ +L
Sbjct: 106 VNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLL 165
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GANIN + +H A GH+ VK ++ H + C ++ TPLH A
Sbjct: 166 LSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLV---SHGA---EVTCKDKKSYTPLHAA 219
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G + + L++ G + + N+Y T A
Sbjct: 220 ASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVA 252
Score = 72.5 bits (170), Expect = 6e-12
Identities = 47/143 (32%), Positives = 71/143 (49%), Gaps = 6/143 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D N T LH AA + L+ +NVN ++ +T LH AA + +++L
Sbjct: 105 DVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKL 164
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL GANINA D +H A+ G+I K+L+S+ ++T + T L A
Sbjct: 165 LLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM 224
Query: 880 LTIID-LID-----NYANKYANT 896
++++ L+D N N Y NT
Sbjct: 225 ISVVKYLLDLGVDMNEPNAYGNT 247
Score = 72.5 bits (170), Expect = 6e-12
Identities = 45/142 (31%), Positives = 75/142 (52%), Gaps = 5/142 (3%)
Query: 754 ESCTDFDVN--VCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAIN 811
+S D N D++G+TALH+A Y E C L+ + A +PLH A IN
Sbjct: 746 QSAASMDANPATADNHGYTALHWAC-YNGHETCVELLLEQEVFQKTEGNAFSPLHCAVIN 804
Query: 812 NKTVVIRLLLDN-GANI-NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKT 869
+ +L+D GA+I NA D TPLH A+ T ++ ++LLS+N + +++T KT
Sbjct: 805 DNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKT 864
Query: 870 ALAVAKDKVHLTIIDLIDNYAN 891
L +A + ++++ + A+
Sbjct: 865 PLMMAAENGQTNTVEMLVSSAS 886
Score = 67.3 bits (157), Expect = 2e-10
Identities = 81/366 (22%), Positives = 154/366 (42%), Gaps = 15/366 (4%)
Query: 523 LNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAE 582
L + +L A G + + L+ ++N ++ +K TPLH A G ++ +I
Sbjct: 12 LRDQPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLIL--- 68
Query: 583 HSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRI 642
SG + +N + TPLH A E ++L++H ++ + ++ +T A +
Sbjct: 69 -SGAR--VNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKA 125
Query: 643 LQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLI 702
++ ++ P L ++++ + + ++ L L + A+ + K
Sbjct: 126 VKCAEALVP-LLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL----SRGANINAFDKKDR 180
Query: 703 ERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCEC-QYCKRKTESCTDFDV 761
I A G +++ + + + A + +KS + H K D+
Sbjct: 181 RAIHWAAYMGHIEVV--KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDM 238
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAIN-NKTVVIRLL 820
N ++ G T LH A G D N LI A VN +N+K TPLH AA + + + + LL
Sbjct: 239 NEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELL 298
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ NGA++N TPLH + G ++ ++ I + T L +A H
Sbjct: 299 VGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHE 358
Query: 881 TIIDLI 886
+I+ +
Sbjct: 359 LLINTL 364
Score = 66.1 bits (154), Expect = 5e-10
Identities = 41/138 (29%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + DS G T LH A+ ++ LL +++N+ D + L A+ G N + ML
Sbjct: 822 VNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEML 881
Query: 545 LHS-GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ S A + ++ KNT LHLA + GH A++ + + R + IN N + TPLH+
Sbjct: 882 VSSASAELTLQDNSKNTALHLACSKGHE--TSALLILEKITDRNL-INATNAALQTPLHV 938
Query: 604 ASKWGYEGIARLLIEHGS 621
A++ G + + L+ G+
Sbjct: 939 AARNGLTMVVQELLGKGA 956
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/163 (26%), Positives = 78/163 (47%), Gaps = 6/163 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++DS LT LH A V+ LL+ +++NA D N + LH A++ L
Sbjct: 73 VNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEAL 132
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +N+N + T LH A +GH VK ++ R NIN ++ +H A
Sbjct: 133 VPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL------SRGANINAFDKKDRRAIHWA 186
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ G+ + +LL+ HG+E + ++ T A + ++ V+K
Sbjct: 187 AYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVK 229
Score = 64.9 bits (151), Expect = 1e-09
Identities = 41/125 (32%), Positives = 66/125 (52%), Gaps = 3/125 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILI--FNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLD 822
+ N F+ LH A + +LI + VN + K +TPLH AA + ++LLL
Sbjct: 791 EGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLS 850
Query: 823 NGANINAIDVARNTPLHDASETGNIGAAKILL-SYNPDITLLNATEKTALAVAKDKVHLT 881
+ A +N++D TPL A+E G ++L+ S + ++TL + ++ TAL +A K H T
Sbjct: 851 HNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHET 910
Query: 882 IIDLI 886
LI
Sbjct: 911 SALLI 915
Score = 63.3 bits (147), Expect = 4e-09
Identities = 40/131 (30%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D +G T L ++ ++G V +LL G+ ++A D +ALH + GH+ + LL
Sbjct: 655 QDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQH 714
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA ++ TP+HL+ GH+ + A++ A + N A+ G T LH A
Sbjct: 715 GAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSA--ASMDANPATADNHGYTALHWACYN 772
Query: 608 GYEGIARLLIE 618
G+E LL+E
Sbjct: 773 GHETCVELLLE 783
Score = 63.3 bits (147), Expect = 4e-09
Identities = 43/142 (30%), Positives = 70/142 (49%), Gaps = 7/142 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLE-MGSEI-NATDLNECSALHYASSRGHQNVLLMLLH 546
+ + + LH A I+ E L++ +G+ I NATD + LH A+ H L +LL
Sbjct: 791 EGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLS 850
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
A +N + TPL +A NG + V+ ++ S + + S NT LHLA
Sbjct: 851 HNAQVNSVDSTGKTPLMMAAENGQTNTVEMLV-----SSASAELTLQDNSKNTALHLACS 905
Query: 607 WGYEGIARLLIEHGSEPSLQNS 628
G+E A L++E ++ +L N+
Sbjct: 906 KGHETSALLILEKITDRNLINA 927
Score = 61.3 bits (142), Expect = 1e-08
Identities = 45/139 (32%), Positives = 73/139 (52%), Gaps = 5/139 (3%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN DS G T LH AA E +L+ + A VN + +TPL +AA N +T + +L
Sbjct: 822 VNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEML 881
Query: 821 LDN-GANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE---KTALAV-AK 875
+ + A + D ++NT LH A G+ +A ++L D L+NAT +T L V A+
Sbjct: 882 VSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAAR 941
Query: 876 DKVHLTIIDLIDNYANKYA 894
+ + + + +L+ A+ A
Sbjct: 942 NGLTMVVQELLGKGASVLA 960
Score = 57.6 bits (133), Expect = 2e-07
Identities = 39/151 (25%), Positives = 73/151 (48%), Gaps = 13/151 (8%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDL---NECSALHYASSRGHQNVLLMLLHSGAN 550
T +H A+ +G + + L+ NA D+ N + L + GH + + LL+ GAN
Sbjct: 625 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 684
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++ K+ T LH GH CV A++ +H + + + G TP+HL++ G+
Sbjct: 685 VDAKDKWGRTALHRGAVTGHEECVDALL---QHGAKCL---LRDSRGRTPIHLSAACGHI 738
Query: 611 GIARLLIEHG----SEPSLQNSYHKTAFDYA 637
G+ L++ + P+ +++ TA +A
Sbjct: 739 GVLGALLQSAASMDANPATADNHGYTALHWA 769
Score = 57.2 bits (132), Expect = 2e-07
Identities = 41/149 (27%), Positives = 74/149 (49%), Gaps = 9/149 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINAT----DLNECSALHYASSRGHQNVLLM 543
RDS G T +H+++ G ++ LL+ + ++A D + +ALH+A GH+ + +
Sbjct: 721 RDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVEL 780
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL + + +PLH AV N + + +I + G I +N + G TPLH
Sbjct: 781 LLEQEV-FQKTEGNAFSPLHCAVINDNEGAAEMLI---DTLGASI-VNATDSKGRTPLHA 835
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKT 632
A+ + +LL+ H ++ + +S KT
Sbjct: 836 AAFTDHVECLQLLLSHNAQVNSVDSTGKT 864
Score = 54.8 bits (126), Expect = 1e-06
Identities = 46/148 (31%), Positives = 71/148 (47%), Gaps = 18/148 (12%)
Query: 488 RDSHGLTALHVASIHGKATIV-----ETLLEMGSEINATDL-----NEC--SALHYASSR 535
RD G A+H ++ +G + ET L++ E + TD+ N S LH A+
Sbjct: 507 RDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYH 566
Query: 536 GHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANE 595
GH L +L+ S +++ +N TPL LA GH+ CV +I + G I +
Sbjct: 567 GHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLI----NQGASILVK-DYI 621
Query: 596 SGNTPLHLASKWGYEGIARLLIEHGSEP 623
TP+H A+ G+ RLLI + +EP
Sbjct: 622 LKRTPIHAAATNGHSECLRLLIGN-AEP 648
Score = 49.6 bits (113), Expect = 5e-05
Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 3/86 (3%)
Query: 755 SCTDFDVNVCDSNGFTALHYAARYGLDEFCNIL---IFNRANVNCRNKKAQTPLHLAAIN 811
S ++ + D++ TALH A G + ++ I +R +N N QTPLH+AA N
Sbjct: 883 SSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARN 942
Query: 812 NKTVVIRLLLDNGANINAIDVARNTP 837
T+V++ LL GA++ A+D TP
Sbjct: 943 GLTMVVQELLGKGASVLAVDENGYTP 968
Score = 48.4 bits (110), Expect = 1e-04
Identities = 38/130 (29%), Positives = 58/130 (44%), Gaps = 4/130 (3%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
V++ D NG T L + G + L+ ANV+ ++K +T LH A+ + L
Sbjct: 652 VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDAL 711
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK----TALAVAKD 876
L +GA D TP+H ++ G+IG LL + AT TAL A
Sbjct: 712 LQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACY 771
Query: 877 KVHLTIIDLI 886
H T ++L+
Sbjct: 772 NGHETCVELL 781
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/137 (27%), Positives = 65/137 (47%), Gaps = 4/137 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNK-KAQTPLHLAAINNKTVVIR 818
D++V +S+G T L AA G E ++LI A++ ++ +TP+H AA N + +R
Sbjct: 581 DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLR 640
Query: 819 LLLDNGANINAIDVA---RNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
LL+ N NA+D+ TPL + G+ LL+ ++ + +TAL
Sbjct: 641 LLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGA 700
Query: 876 DKVHLTIIDLIDNYANK 892
H +D + + K
Sbjct: 701 VTGHEECVDALLQHGAK 717
Score = 41.5 bits (93), Expect = 0.013
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 4/99 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ D G TALH A G +E + L+ + A R+ + +TP+HL+A V+
Sbjct: 684 NVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 743
Query: 820 LLDNGANINA----IDVARNTPLHDASETGNIGAAKILL 854
LL + A+++A D T LH A G+ ++LL
Sbjct: 744 LLQSAASMDANPATADNHGYTALHWACYNGHETCVELLL 782
Score = 36.3 bits (80), Expect = 0.48
Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSE---INATDLNECSALHYASSRGHQNVL 541
+T +D+ TALH+A G T +LE ++ INAT+ + LH A+ G V+
Sbjct: 889 LTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVV 948
Query: 542 LMLLHSGANINQKNIDKNTP-LHLAVNNGHLHCVKAII 578
LL GA++ + + TP L A N C+ I+
Sbjct: 949 QELLGKGASVLAVDENGYTPALACAPNKDVADCLALIL 986
>BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein.
Length = 579
Score = 104 bits (249), Expect = 2e-21
Identities = 113/437 (25%), Positives = 191/437 (43%), Gaps = 45/437 (10%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYA-SSRGHQNVLLMLLHS 547
DS T LHVA+ G A I+E L+ G+ +NA D + LH A +SR + V +++ HS
Sbjct: 38 DSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHS 97
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAI------IYFAEHSGRKI------------- 588
A++N ++ + TPLH+A N + C + I + ++ GR
Sbjct: 98 -ADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMV 156
Query: 589 --------NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNL 640
NIN ++ LH A+ G+ + LLI HG+E + ++ T A +
Sbjct: 157 NLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASN 216
Query: 641 RILQVLKSCTPNL---FEYIHITSSEVKKISCESEKPTSL-KLQNLTLKCSDTNDASKTI 696
+ V+K NL + I++ + I+C + + + +L + + N+ T
Sbjct: 217 GQINVVKHLL-NLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTP 275
Query: 697 ENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLC-ECQYCKRKTES 755
+ A ++G + C + ++ A + + S H ++ + +T
Sbjct: 276 LHFAA------ASTHGAL---CLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLI 326
Query: 756 CTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTV 815
+++ D +G T LH AARYG + N LI + A+ + PLHLAA+N +
Sbjct: 327 QNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSD 386
Query: 816 VIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
R LL +G I+ D T LH A+ GN+ K+L S D + +T L A
Sbjct: 387 CCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAA 446
Query: 876 DKVHLTIID-LIDNYAN 891
H I+ L+ AN
Sbjct: 447 ANCHFHCIETLVTTGAN 463
Score = 92.3 bits (219), Expect = 7e-18
Identities = 87/351 (24%), Positives = 158/351 (45%), Gaps = 17/351 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A G + L+ ++N D + + LH A+ G ++ +L+ SGA +N K+
Sbjct: 15 AIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMW 74
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH AV + V+ +I +HS ++N +++ TPLH+A+ A ++I
Sbjct: 75 LTPLHRAVASRSEEAVQVLI---KHSA---DVNARDKNWQTPLHVAAANKAVKCAEVIIP 128
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLK 678
S ++ + +TA H+ + ++ L + +I + + K
Sbjct: 129 LLSSVNVSDRGGRTAL---HHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGH 185
Query: 679 LQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNS 738
L + L + + A T ++ K + A S G + + +N+ I N+
Sbjct: 186 LDVVALLIN--HGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVE--IDEINVYGNT 241
Query: 739 LCHPLCECQYCKRKTESCTDF--DVNVCDSNGFTALHYAARYGLDEFC-NILIFNRANVN 795
H C D+ +VN ++NGFT LH+AA C +L+ N A+VN
Sbjct: 242 ALHIAC-YNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVN 300
Query: 796 CRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
++K ++PLH+ A++ + + L+ NG I+ +D NTPLH A+ G+
Sbjct: 301 IQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGH 351
Score = 92.3 bits (219), Expect = 7e-18
Identities = 98/368 (26%), Positives = 156/368 (42%), Gaps = 28/368 (7%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T +D G T LH A+ +G+ +V+ LL +G EI+ ++ +ALH A G V+ L
Sbjct: 199 VTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNEL 258
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGH-LHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ GAN+NQ N + TPLH A + H C++ ++ ++G +NI ++ G +PLH+
Sbjct: 259 IDYGANVNQPNNNGFTPLHFAAASTHGALCLELLV----NNGADVNIQ--SKDGKSPLHM 312
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKT----AFDYAHNLRILQVLKSCTPNLFEYIH- 658
+ G ++ LI++G E + T A Y H L I ++ S IH
Sbjct: 313 TAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHS 372
Query: 659 ITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLAC 718
+ + ++ S+ L + DT D K L A + G
Sbjct: 373 MFPLHLAALNAHSDCCRKLLSSGFEI---DTPD--------KFGRTCLHAAAAGGNVECI 421
Query: 719 FYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
+ + F DK L + C + +T T +VN D G TALHYAA
Sbjct: 422 KLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAAS 481
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPL 838
+D N I A+ N + L T+ + LL N AN + D +
Sbjct: 482 DMDR--NKTILGNAHDNSEELERAREL---KEKEATLCLEFLLQNDANPSIRDKEGYNSI 536
Query: 839 HDASETGN 846
H A+ G+
Sbjct: 537 HYAAAYGH 544
Score = 79.0 bits (186), Expect = 7e-14
Identities = 49/153 (32%), Positives = 74/153 (48%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +RD + T LHVA+ + E ++ + S +N +D +ALH+A+ GH ++ +L
Sbjct: 100 VNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLL 159
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GANIN + LH A GHL V +I H + C ++ G TPLH A
Sbjct: 160 LAKGANINAFDKKDRRALHWAAYMGHLDVVALLI---NHGA---EVTCKDKKGYTPLHAA 213
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G + + L+ G E N Y TA A
Sbjct: 214 ASNGQINVVKHLLNLGVEIDEINVYGNTALHIA 246
Score = 69.3 bits (162), Expect = 6e-11
Identities = 39/127 (30%), Positives = 66/127 (51%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN DS T LH AA G E +LI + A VN ++ TPLH A + +++
Sbjct: 33 DVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQV 92
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ + A++NA D TPLH A+ + A++++ + + + +TAL A H
Sbjct: 93 LIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGH 152
Query: 880 LTIIDLI 886
+ +++L+
Sbjct: 153 VEMVNLL 159
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/96 (33%), Positives = 52/96 (54%)
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPL 838
G E +LI +VN + + +TPLH+AA +I LL+ +GA +NA D TPL
Sbjct: 19 GDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPL 78
Query: 839 HDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
H A + + A ++L+ ++ D+ + +T L VA
Sbjct: 79 HRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVA 114
Score = 46.0 bits (104), Expect = 6e-04
Identities = 30/115 (26%), Positives = 51/115 (44%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D C + LH AA + C L+ + ++ +K +T LH AA I+L
Sbjct: 364 DTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKL 423
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
L +GA+ + D TPLH A+ + + L++ ++ + +TAL A
Sbjct: 424 LQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYA 478
Score = 32.7 bits (71), Expect = 5.9
Identities = 16/53 (30%), Positives = 28/53 (52%)
Query: 802 QTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
Q PL A + IR+L+ ++N +D + TPLH A+ G+ ++L+
Sbjct: 9 QPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLI 61
>AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein.
Length = 525
Score = 104 bits (249), Expect = 2e-21
Identities = 113/437 (25%), Positives = 191/437 (43%), Gaps = 45/437 (10%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYA-SSRGHQNVLLMLLHS 547
DS T LHVA+ G A I+E L+ G+ +NA D + LH A +SR + V +++ HS
Sbjct: 13 DSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHS 72
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAI------IYFAEHSGRKI------------- 588
A++N ++ + TPLH+A N + C + I + ++ GR
Sbjct: 73 -ADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMV 131
Query: 589 --------NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNL 640
NIN ++ LH A+ G+ + LLI HG+E + ++ T A +
Sbjct: 132 NLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASN 191
Query: 641 RILQVLKSCTPNL---FEYIHITSSEVKKISCESEKPTSL-KLQNLTLKCSDTNDASKTI 696
+ V+K NL + I++ + I+C + + + +L + + N+ T
Sbjct: 192 GQINVVKHLL-NLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTP 250
Query: 697 ENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLC-ECQYCKRKTES 755
+ A ++G + C + ++ A + + S H ++ + +T
Sbjct: 251 LHFAA------ASTHGAL---CLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLI 301
Query: 756 CTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTV 815
+++ D +G T LH AARYG + N LI + A+ + PLHLAA+N +
Sbjct: 302 QNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSD 361
Query: 816 VIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
R LL +G I+ D T LH A+ GN+ K+L S D + +T L A
Sbjct: 362 CCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAA 421
Query: 876 DKVHLTIID-LIDNYAN 891
H I+ L+ AN
Sbjct: 422 ANCHFHCIETLVTTGAN 438
Score = 92.3 bits (219), Expect = 7e-18
Identities = 98/368 (26%), Positives = 156/368 (42%), Gaps = 28/368 (7%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T +D G T LH A+ +G+ +V+ LL +G EI+ ++ +ALH A G V+ L
Sbjct: 174 VTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNEL 233
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGH-LHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ GAN+NQ N + TPLH A + H C++ ++ ++G +NI ++ G +PLH+
Sbjct: 234 IDYGANVNQPNNNGFTPLHFAAASTHGALCLELLV----NNGADVNIQ--SKDGKSPLHM 287
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKT----AFDYAHNLRILQVLKSCTPNLFEYIH- 658
+ G ++ LI++G E + T A Y H L I ++ S IH
Sbjct: 288 TAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHS 347
Query: 659 ITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLAC 718
+ + ++ S+ L + DT D K L A + G
Sbjct: 348 MFPLHLAALNAHSDCCRKLLSSGFEI---DTPD--------KFGRTCLHAAAAGGNVECI 396
Query: 719 FYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
+ + F DK L + C + +T T +VN D G TALHYAA
Sbjct: 397 KLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAAS 456
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPL 838
+D N I A+ N + L T+ + LL N AN + D +
Sbjct: 457 DMDR--NKTILGNAHDNSEELERAREL---KEKEATLCLEFLLQNDANPSIRDKEGYNSI 511
Query: 839 HDASETGN 846
H A+ G+
Sbjct: 512 HYAAAYGH 519
Score = 91.1 bits (216), Expect = 2e-17
Identities = 85/339 (25%), Positives = 155/339 (45%), Gaps = 17/339 (5%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
L+ ++N D + + LH A+ G ++ +L+ SGA +N K+ TPLH AV +
Sbjct: 2 LIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRS 61
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH 630
V+ +I +HS ++N +++ TPLH+A+ A ++I S ++ +
Sbjct: 62 EEAVQVLI---KHSA---DVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGG 115
Query: 631 KTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTN 690
+TA H+ + ++ L + +I + + K L + L + +
Sbjct: 116 RTAL---HHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLIN--H 170
Query: 691 DASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCK 750
A T ++ K + A S G + + +N+ I N+ H C
Sbjct: 171 GAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVE--IDEINVYGNTALHIAC-YNGQD 227
Query: 751 RKTESCTDF--DVNVCDSNGFTALHYAARYGLDEFC-NILIFNRANVNCRNKKAQTPLHL 807
D+ +VN ++NGFT LH+AA C +L+ N A+VN ++K ++PLH+
Sbjct: 228 AVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHM 287
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
A++ + + L+ NG I+ +D NTPLH A+ G+
Sbjct: 288 TAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGH 326
Score = 79.0 bits (186), Expect = 7e-14
Identities = 49/153 (32%), Positives = 74/153 (48%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +RD + T LHVA+ + E ++ + S +N +D +ALH+A+ GH ++ +L
Sbjct: 75 VNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLL 134
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GANIN + LH A GHL V +I H + C ++ G TPLH A
Sbjct: 135 LAKGANINAFDKKDRRALHWAAYMGHLDVVALLI---NHGA---EVTCKDKKGYTPLHAA 188
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G + + L+ G E N Y TA A
Sbjct: 189 ASNGQINVVKHLLNLGVEIDEINVYGNTALHIA 221
Score = 77.0 bits (181), Expect = 3e-13
Identities = 83/346 (23%), Positives = 147/346 (42%), Gaps = 15/346 (4%)
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
ML+H ++N + +K TPLH+A G ++ +I SG + +N + TPLH
Sbjct: 1 MLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLIL----SGAR--VNAKDNMWLTPLH 54
Query: 603 LASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSS 662
A E ++LI+H ++ + ++ +T A + ++ + P L ++++
Sbjct: 55 RAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIP-LLSSVNVSDR 113
Query: 663 EVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISY-GDVKLACFYM 721
+ + +++ NL L +A K R L +Y G + + +
Sbjct: 114 GGRTALHHAALNGHVEMVNLLLAKGANINAFD-----KKDRRALHWAAYMGHLDVVALLI 168
Query: 722 NIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLD 781
N + DK+ L Q K +++ + G TALH A G D
Sbjct: 169 N-HGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQD 227
Query: 782 EFCNILIFNRANVNCRNKKAQTPLHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHD 840
N LI ANVN N TPLH AA + + + + LL++NGA++N +PLH
Sbjct: 228 AVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHM 287
Query: 841 ASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+ G ++ L+ +I ++ T L VA H +I+ +
Sbjct: 288 TAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTL 333
Score = 46.0 bits (104), Expect = 6e-04
Identities = 30/115 (26%), Positives = 51/115 (44%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D C + LH AA + C L+ + ++ +K +T LH AA I+L
Sbjct: 339 DTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKL 398
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
L +GA+ + D TPLH A+ + + L++ ++ + +TAL A
Sbjct: 399 LQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYA 453
>AL834335-1|CAD39003.1| 407|Homo sapiens hypothetical protein
protein.
Length = 407
Score = 99.1 bits (236), Expect = 6e-20
Identities = 65/202 (32%), Positives = 105/202 (51%), Gaps = 14/202 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+TS+D G + LHVA++HG+A ++ LL+ G+ A + ++ LH A +GH V+ L
Sbjct: 96 VTSQD--GSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCL 153
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L S A N+K++ NTPL A + GH V ++ +H +IN +N GNT LH A
Sbjct: 154 LDSNAKPNKKDLSGNTPLIYACSGGHHELVALLL---QHGA---SINASNNKGNTALHEA 207
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHN----LRILQVLKSCTPNLFEYIHIT 660
+ + LL+ HG+ + N +TA D A + +LQV+ SC +L +
Sbjct: 208 VIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDDVAETD 267
Query: 661 SSEVKKISCESEKPTSLKLQNL 682
E ++ + K + KL +L
Sbjct: 268 RKEY--VTVKIRKKWNSKLYDL 287
Score = 93.9 bits (223), Expect = 2e-18
Identities = 62/210 (29%), Positives = 106/210 (50%), Gaps = 12/210 (5%)
Query: 687 SDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNS-----LCH 741
S ++ +T ++ + +E++LRA++ GD+++ + + +++ D E + S CH
Sbjct: 12 SASSRQEETKKDYREVEKLLRAVADGDLEMVRYLL--EWTEEDLEDAEDTVSAADPEFCH 69
Query: 742 PLCECQYC----KRKTE-SCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC 796
PLC+C C KR + + VNV +G + LH AA +G + +L+ + AN
Sbjct: 70 PLCQCPKCAPAQKRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGA 129
Query: 797 RNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSY 856
RN PLHLA V++ LLD+ A N D++ NTPL A G+ +LL +
Sbjct: 130 RNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQH 189
Query: 857 NPDITLLNATEKTALAVAKDKVHLTIIDLI 886
I N TAL A + H+ +++L+
Sbjct: 190 GASINASNNKGNTALHEAVIEKHVFVVELL 219
Score = 72.1 bits (169), Expect = 8e-12
Identities = 43/123 (34%), Positives = 62/123 (50%), Gaps = 6/123 (4%)
Query: 515 GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCV 574
G +N T + S LH A+ G +++ +LL GAN +N D+ PLHLA GH V
Sbjct: 91 GLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVV 150
Query: 575 KAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAF 634
K ++ S K N + SGNTPL A G+ + LL++HG+ + N+ TA
Sbjct: 151 KCLL----DSNAKPNKK--DLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTAL 204
Query: 635 DYA 637
A
Sbjct: 205 HEA 207
Score = 54.4 bits (125), Expect = 2e-06
Identities = 31/104 (29%), Positives = 54/104 (51%)
Query: 772 LHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID 831
LH A + G + L+ + A N ++ TPL A ++ LLL +GA+INA +
Sbjct: 138 LHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASN 197
Query: 832 VARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
NT LH+A ++ ++LL + + +LN ++TA+ A+
Sbjct: 198 NKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAE 241
Score = 50.0 bits (114), Expect = 4e-05
Identities = 28/86 (32%), Positives = 43/86 (50%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N D +G T L YA G E +L+ + A++N N K T LH A I V+ LLL
Sbjct: 161 NKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELLL 220
Query: 822 DNGANINAIDVARNTPLHDASETGNI 847
+GA++ ++ + T + A + I
Sbjct: 221 LHGASVQVLNKRQRTAVDCAEQNSKI 246
Score = 40.7 bits (91), Expect = 0.022
Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 7/130 (5%)
Query: 509 ETLLEMGSEINATDLNECSAL-HYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVN 567
E L + ++A D C L Q L + SG +N + D ++PLH+A
Sbjct: 51 EDLEDAEDTVSAADPEFCHPLCQCPKCAPAQKRLAKVPASGLGVNVTSQDGSSPLHVAAL 110
Query: 568 NGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQN 627
+G + ++ ++G + N PLHLA + G+ + + L++ ++P+ ++
Sbjct: 111 HGRADLIPLLLKHGANAGAR------NADQAVPLHLACQQGHFQVVKCLLDSNAKPNKKD 164
Query: 628 SYHKTAFDYA 637
T YA
Sbjct: 165 LSGNTPLIYA 174
Score = 35.9 bits (79), Expect = 0.64
Identities = 19/75 (25%), Positives = 35/75 (46%)
Query: 573 CVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKT 632
C A A+ + +N ++ G++PLH+A+ G + LL++HG+ +N+
Sbjct: 77 CAPAQKRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAV 136
Query: 633 AFDYAHNLRILQVLK 647
A QV+K
Sbjct: 137 PLHLACQQGHFQVVK 151
>D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein.
Length = 226
Score = 96.7 bits (230), Expect = 3e-19
Identities = 51/153 (33%), Positives = 83/153 (54%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +D G + LH+A+ G+ IV+ LL G+++NA + N C+ LHYA+S+ + +ML
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GAN + K+ + T +H A G+L + ++Y+ K + N + GNTPLHLA
Sbjct: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY------KASTNIQDTEGNTPLHLA 179
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A+LL+ G+ ++N KT A
Sbjct: 180 CDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 78.6 bits (185), Expect = 9e-14
Identities = 47/141 (33%), Positives = 75/141 (53%), Gaps = 9/141 (6%)
Query: 509 ETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNN 568
E++L S TD + +ALH+A S GH ++ LL G +N K+ +PLH+A +
Sbjct: 24 ESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASA 83
Query: 569 GHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNS 628
G VKA++ G+ +N N++G TPLH A+ IA +L+E G+ P ++
Sbjct: 84 GRDEIVKALL------GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH 137
Query: 629 YHKTAFDYA---HNLRILQVL 646
Y TA A NL+++ +L
Sbjct: 138 YEATAMHRAAAKGNLKMIHIL 158
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/127 (34%), Positives = 64/127 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN + NG T LHYAA E +L+ AN + ++ T +H AA +I +L
Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L A+ N D NTPLH A + + AK+L+S I + N EKT L VAK + L
Sbjct: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGL 218
Query: 881 TIIDLID 887
+ +++
Sbjct: 219 ILKRMVE 225
Score = 72.5 bits (170), Expect = 6e-12
Identities = 43/117 (36%), Positives = 59/117 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G++ LH AA G DE L+ A VN N+ TPLH AA N+ + +L
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
L+ GAN +A D T +H A+ GN+ ILL Y + + T L +A D+
Sbjct: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDE 182
Score = 58.8 bits (136), Expect = 8e-08
Identities = 46/154 (29%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T T +DS TALH A G IVE LL++G +N D S LH A+S G ++
Sbjct: 34 TRTDQDSR--TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKA 91
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GA +N N + TPLH A + H + ++ G N + + T +H
Sbjct: 92 LLGKGAQVNAVNQNGCTPLHYAASKNR-HEIAVMLL---EGG--ANPDAKDHYEATAMHR 145
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A+ G + +L+ + + ++Q++ T A
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
Score = 58.8 bits (136), Expect = 8e-08
Identities = 38/125 (30%), Positives = 61/125 (48%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D + TALH+A G E L+ VN ++ +PLH+AA + +++ LL G
Sbjct: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
A +NA++ TPLH A+ A +LL + + E TA+ A K +L +I
Sbjct: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
Query: 885 LIDNY 889
++ Y
Sbjct: 157 ILLYY 161
Score = 42.3 bits (95), Expect = 0.007
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Query: 780 LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLH 839
L+E ++ +++ ++ ++T LH A T ++ LL G +N D A +PLH
Sbjct: 19 LEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLH 78
Query: 840 DASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK-VHLTIIDLIDNYAN 891
A+ G K LL + +N T L A K H + L++ AN
Sbjct: 79 IAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN 131
>BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 96.7 bits (230), Expect = 3e-19
Identities = 51/153 (33%), Positives = 83/153 (54%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +D G + LH+A+ G+ IV+ LL G+++NA + N C+ LHYA+S+ + +ML
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GAN + K+ + T +H A G+L + ++Y+ K + N + GNTPLHLA
Sbjct: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY------KASTNIQDTEGNTPLHLA 179
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A+LL+ G+ ++N KT A
Sbjct: 180 CDEERVEEAKLLVSQGTSIYIENKEEKTPLQVA 212
Score = 78.6 bits (185), Expect = 9e-14
Identities = 47/141 (33%), Positives = 75/141 (53%), Gaps = 9/141 (6%)
Query: 509 ETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNN 568
E++L S TD + +ALH+A S GH ++ LL G +N K+ +PLH+A +
Sbjct: 24 ESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASA 83
Query: 569 GHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNS 628
G VKA++ G+ +N N++G TPLH A+ IA +L+E G+ P ++
Sbjct: 84 GRDEIVKALL------GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH 137
Query: 629 YHKTAFDYA---HNLRILQVL 646
Y TA A NL+++ +L
Sbjct: 138 YEATAMHRAAAKGNLKMIHIL 158
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/127 (34%), Positives = 64/127 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN + NG T LHYAA E +L+ AN + ++ T +H AA +I +L
Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L A+ N D NTPLH A + + AK+L+S I + N EKT L VAK + L
Sbjct: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGTSIYIENKEEKTPLQVAKGGLGL 218
Query: 881 TIIDLID 887
+ +++
Sbjct: 219 ILKRMVE 225
Score = 72.5 bits (170), Expect = 6e-12
Identities = 43/117 (36%), Positives = 59/117 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G++ LH AA G DE L+ A VN N+ TPLH AA N+ + +L
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
L+ GAN +A D T +H A+ GN+ ILL Y + + T L +A D+
Sbjct: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDE 182
Score = 58.8 bits (136), Expect = 8e-08
Identities = 46/154 (29%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T T +DS TALH A G IVE LL++G +N D S LH A+S G ++
Sbjct: 34 TRTDQDSR--TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKA 91
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GA +N N + TPLH A + H + ++ G N + + T +H
Sbjct: 92 LLGKGAQVNAVNQNGCTPLHYAASKNR-HEIAVMLL---EGG--ANPDAKDHYEATAMHR 145
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A+ G + +L+ + + ++Q++ T A
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
Score = 58.8 bits (136), Expect = 8e-08
Identities = 38/125 (30%), Positives = 61/125 (48%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D + TALH+A G E L+ VN ++ +PLH+AA + +++ LL G
Sbjct: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
A +NA++ TPLH A+ A +LL + + E TA+ A K +L +I
Sbjct: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
Query: 885 LIDNY 889
++ Y
Sbjct: 157 ILLYY 161
Score = 42.3 bits (95), Expect = 0.007
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Query: 780 LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLH 839
L+E ++ +++ ++ ++T LH A T ++ LL G +N D A +PLH
Sbjct: 19 LEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLH 78
Query: 840 DASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK-VHLTIIDLIDNYAN 891
A+ G K LL + +N T L A K H + L++ AN
Sbjct: 79 IAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN 131
>BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 96.7 bits (230), Expect = 3e-19
Identities = 51/153 (33%), Positives = 83/153 (54%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +D G + LH+A+ G+ IV+ LL G+++NA + N C+ LHYA+S+ + +ML
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GAN + K+ + T +H A G+L + ++Y+ K + N + GNTPLHLA
Sbjct: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY------KASTNIQDTEGNTPLHLA 179
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A+LL+ G+ ++N KT A
Sbjct: 180 CDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 78.6 bits (185), Expect = 9e-14
Identities = 47/141 (33%), Positives = 75/141 (53%), Gaps = 9/141 (6%)
Query: 509 ETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNN 568
E++L S TD + +ALH+A S GH ++ LL G +N K+ +PLH+A +
Sbjct: 24 ESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASA 83
Query: 569 GHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNS 628
G VKA++ G+ +N N++G TPLH A+ IA +L+E G+ P ++
Sbjct: 84 GRDEIVKALL------GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH 137
Query: 629 YHKTAFDYA---HNLRILQVL 646
Y TA A NL+++ +L
Sbjct: 138 YEATAMHRAAAKGNLKMIHIL 158
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/127 (34%), Positives = 64/127 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN + NG T LHYAA E +L+ AN + ++ T +H AA +I +L
Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L A+ N D NTPLH A + + AK+L+S I + N EKT L VAK + L
Sbjct: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGL 218
Query: 881 TIIDLID 887
+ +++
Sbjct: 219 ILKRMVE 225
Score = 72.5 bits (170), Expect = 6e-12
Identities = 43/117 (36%), Positives = 59/117 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G++ LH AA G DE L+ A VN N+ TPLH AA N+ + +L
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
L+ GAN +A D T +H A+ GN+ ILL Y + + T L +A D+
Sbjct: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDE 182
Score = 58.8 bits (136), Expect = 8e-08
Identities = 46/154 (29%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T T +DS TALH A G IVE LL++G +N D S LH A+S G ++
Sbjct: 34 TRTDQDSR--TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKA 91
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GA +N N + TPLH A + H + ++ G N + + T +H
Sbjct: 92 LLGKGAQVNAVNQNGCTPLHYAASKNR-HEIAVMLL---EGG--ANPDAKDHYEATAMHR 145
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A+ G + +L+ + + ++Q++ T A
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
Score = 58.8 bits (136), Expect = 8e-08
Identities = 38/125 (30%), Positives = 61/125 (48%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D + TALH+A G E L+ VN ++ +PLH+AA + +++ LL G
Sbjct: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
A +NA++ TPLH A+ A +LL + + E TA+ A K +L +I
Sbjct: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
Query: 885 LIDNY 889
++ Y
Sbjct: 157 ILLYY 161
Score = 42.3 bits (95), Expect = 0.007
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Query: 780 LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLH 839
L+E ++ +++ ++ ++T LH A T ++ LL G +N D A +PLH
Sbjct: 19 LEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLH 78
Query: 840 DASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK-VHLTIIDLIDNYAN 891
A+ G K LL + +N T L A K H + L++ AN
Sbjct: 79 IAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN 131
>AL031177-5|CAA20117.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 96.7 bits (230), Expect = 3e-19
Identities = 51/153 (33%), Positives = 83/153 (54%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +D G + LH+A+ G+ IV+ LL G+++NA + N C+ LHYA+S+ + +ML
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GAN + K+ + T +H A G+L + ++Y+ K + N + GNTPLHLA
Sbjct: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY------KASTNIQDTEGNTPLHLA 179
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A+LL+ G+ ++N KT A
Sbjct: 180 CDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 78.6 bits (185), Expect = 9e-14
Identities = 47/141 (33%), Positives = 75/141 (53%), Gaps = 9/141 (6%)
Query: 509 ETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNN 568
E++L S TD + +ALH+A S GH ++ LL G +N K+ +PLH+A +
Sbjct: 24 ESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASA 83
Query: 569 GHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNS 628
G VKA++ G+ +N N++G TPLH A+ IA +L+E G+ P ++
Sbjct: 84 GRDEIVKALL------GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH 137
Query: 629 YHKTAFDYA---HNLRILQVL 646
Y TA A NL+++ +L
Sbjct: 138 YEATAMHRAAAKGNLKMIHIL 158
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/127 (34%), Positives = 64/127 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN + NG T LHYAA E +L+ AN + ++ T +H AA +I +L
Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L A+ N D NTPLH A + + AK+L+S I + N EKT L VAK + L
Sbjct: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGL 218
Query: 881 TIIDLID 887
+ +++
Sbjct: 219 ILKRMVE 225
Score = 72.5 bits (170), Expect = 6e-12
Identities = 43/117 (36%), Positives = 59/117 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G++ LH AA G DE L+ A VN N+ TPLH AA N+ + +L
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
L+ GAN +A D T +H A+ GN+ ILL Y + + T L +A D+
Sbjct: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDE 182
Score = 58.8 bits (136), Expect = 8e-08
Identities = 46/154 (29%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T T +DS TALH A G IVE LL++G +N D S LH A+S G ++
Sbjct: 34 TRTDQDSR--TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKA 91
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GA +N N + TPLH A + H + ++ G N + + T +H
Sbjct: 92 LLGKGAQVNAVNQNGCTPLHYAASKNR-HEIAVMLL---EGG--ANPDAKDHYEATAMHR 145
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A+ G + +L+ + + ++Q++ T A
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
Score = 58.8 bits (136), Expect = 8e-08
Identities = 38/125 (30%), Positives = 61/125 (48%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D + TALH+A G E L+ VN ++ +PLH+AA + +++ LL G
Sbjct: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
A +NA++ TPLH A+ A +LL + + E TA+ A K +L +I
Sbjct: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
Query: 885 LIDNY 889
++ Y
Sbjct: 157 ILLYY 161
Score = 42.3 bits (95), Expect = 0.007
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Query: 780 LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLH 839
L+E ++ +++ ++ ++T LH A T ++ LL G +N D A +PLH
Sbjct: 19 LEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLH 78
Query: 840 DASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK-VHLTIIDLIDNYAN 891
A+ G K LL + +N T L A K H + L++ AN
Sbjct: 79 IAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN 131
>AL031177-4|CAI43134.1| 193|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 193
Score = 96.7 bits (230), Expect = 3e-19
Identities = 52/152 (34%), Positives = 82/152 (53%), Gaps = 6/152 (3%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
T D G + LH+A+ G+ IV+ LL G+++NA + N C+ LHYA+S+ + +MLL
Sbjct: 34 TRTDQAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLL 93
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GAN + K+ + T +H A G+L + ++Y+ K + N + GNTPLHLA
Sbjct: 94 EGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY------KASTNIQDTEGNTPLHLAC 147
Query: 606 KWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A+LL+ G+ ++N KT A
Sbjct: 148 DEERVEEAKLLVSQGASIYIENKEEKTPLQVA 179
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/127 (34%), Positives = 64/127 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN + NG T LHYAA E +L+ AN + ++ T +H AA +I +L
Sbjct: 66 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 125
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L A+ N D NTPLH A + + AK+L+S I + N EKT L VAK + L
Sbjct: 126 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGL 185
Query: 881 TIIDLID 887
+ +++
Sbjct: 186 ILKRMVE 192
Score = 70.9 bits (166), Expect = 2e-11
Identities = 41/113 (36%), Positives = 57/113 (50%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G++ LH AA G DE L+ A VN N+ TPLH AA N+ + +LL+ G
Sbjct: 37 DQAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 96
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
AN +A D T +H A+ GN+ ILL Y + + T L +A D+
Sbjct: 97 ANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDE 149
Score = 46.0 bits (104), Expect = 6e-04
Identities = 29/110 (26%), Positives = 55/110 (50%)
Query: 780 LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLH 839
L+E ++ +++ ++ +PLH+AA + +++ LL GA +NA++ TPLH
Sbjct: 19 LEELKESILADKSLATRTDQAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLH 78
Query: 840 DASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
A+ A +LL + + E TA+ A K +L +I ++ Y
Sbjct: 79 YAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY 128
Score = 39.5 bits (88), Expect = 0.052
Identities = 33/129 (25%), Positives = 57/129 (44%), Gaps = 6/129 (4%)
Query: 509 ETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNN 568
E++L S TD S LH A+S G ++ LL GA +N N + TPLH A +
Sbjct: 24 ESILADKSLATRTDQAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASK 83
Query: 569 GHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNS 628
H + ++ G N + + T +H A+ G + +L+ + + ++Q++
Sbjct: 84 NR-HEIAVMLL---EGG--ANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDT 137
Query: 629 YHKTAFDYA 637
T A
Sbjct: 138 EGNTPLHLA 146
>AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit p28
protein.
Length = 226
Score = 96.7 bits (230), Expect = 3e-19
Identities = 51/153 (33%), Positives = 83/153 (54%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +D G + LH+A+ G+ IV+ LL G+++NA + N C+ LHYA+S+ + +ML
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GAN + K+ + T +H A G+L + ++Y+ K + N + GNTPLHLA
Sbjct: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY------KASTNIQDTEGNTPLHLA 179
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A+LL+ G+ ++N KT A
Sbjct: 180 CDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 78.6 bits (185), Expect = 9e-14
Identities = 47/141 (33%), Positives = 75/141 (53%), Gaps = 9/141 (6%)
Query: 509 ETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNN 568
E++L S TD + +ALH+A S GH ++ LL G +N K+ +PLH+A +
Sbjct: 24 ESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASA 83
Query: 569 GHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNS 628
G VKA++ G+ +N N++G TPLH A+ IA +L+E G+ P ++
Sbjct: 84 GRDEIVKALL------GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH 137
Query: 629 YHKTAFDYA---HNLRILQVL 646
Y TA A NL+++ +L
Sbjct: 138 YEATAMHRAAAKGNLKMIHIL 158
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/127 (34%), Positives = 64/127 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN + NG T LHYAA E +L+ AN + ++ T +H AA +I +L
Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L A+ N D NTPLH A + + AK+L+S I + N EKT L VAK + L
Sbjct: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGL 218
Query: 881 TIIDLID 887
+ +++
Sbjct: 219 ILKRMVE 225
Score = 72.5 bits (170), Expect = 6e-12
Identities = 43/117 (36%), Positives = 59/117 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G++ LH AA G DE L+ A VN N+ TPLH AA N+ + +L
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
L+ GAN +A D T +H A+ GN+ ILL Y + + T L +A D+
Sbjct: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDE 182
Score = 58.8 bits (136), Expect = 8e-08
Identities = 46/154 (29%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T T +DS TALH A G IVE LL++G +N D S LH A+S G ++
Sbjct: 34 TRTDQDSR--TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKA 91
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GA +N N + TPLH A + H + ++ G N + + T +H
Sbjct: 92 LLGKGAQVNAVNQNGCTPLHYAASKNR-HEIAVMLL---EGG--ANPDAKDHYEATAMHR 145
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A+ G + +L+ + + ++Q++ T A
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
Score = 58.8 bits (136), Expect = 8e-08
Identities = 38/125 (30%), Positives = 61/125 (48%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D + TALH+A G E L+ VN ++ +PLH+AA + +++ LL G
Sbjct: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
A +NA++ TPLH A+ A +LL + + E TA+ A K +L +I
Sbjct: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
Query: 885 LIDNY 889
++ Y
Sbjct: 157 ILLYY 161
Score = 42.3 bits (95), Expect = 0.007
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Query: 780 LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLH 839
L+E ++ +++ ++ ++T LH A T ++ LL G +N D A +PLH
Sbjct: 19 LEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLH 78
Query: 840 DASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK-VHLTIIDLIDNYAN 891
A+ G K LL + +N T L A K H + L++ AN
Sbjct: 79 IAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN 131
>X83703-1|CAA58676.1| 319|Homo sapiens nuclear protein protein.
Length = 319
Score = 96.3 bits (229), Expect = 4e-19
Identities = 53/147 (36%), Positives = 86/147 (58%), Gaps = 6/147 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D + TALH A + G IVE L+E G++I D+ E +A+H+AS G+ +VL +LL+ G
Sbjct: 150 DEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKG 209
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A I+ ++ +T LH+AV GH C + +I + ++N + G+TPLH A +
Sbjct: 210 AKISARDKLLSTALHVAVRTGHYECAEHLI------ACEADLNAKDREGDTPLHDAVRLN 263
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFD 635
+ RLLI +G++ +++N KT D
Sbjct: 264 RYKMIRLLIMYGADLNIKNCAGKTPMD 290
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/121 (34%), Positives = 62/121 (51%), Gaps = 8/121 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
RD TA+H AS G +++ LL G++I+A D +ALH A GH L+
Sbjct: 182 RDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIAC 241
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKINI-NCANESGNTPLHLASK 606
A++N K+ + +TPLH AV ++ +I + G +NI NCA G TP+ L
Sbjct: 242 EADLNAKDREGDTPLHDAVRLNRYKMIRLLIMY----GADLNIKNCA---GKTPMDLVLH 294
Query: 607 W 607
W
Sbjct: 295 W 295
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/102 (30%), Positives = 51/102 (50%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TA+H+A+R G + +L+ A ++ R+K T LH+A L+ A++NA
Sbjct: 188 TAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNA 247
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
D +TPLHDA ++L+ Y D+ + N KT +
Sbjct: 248 KDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPM 289
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/125 (32%), Positives = 58/125 (46%), Gaps = 3/125 (2%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
+VCD TALH A G L+ A + R+ T +H A+ V++LLL
Sbjct: 147 DVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLL 206
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ GA I+A D +T LH A TG+ A+ L++ D LNA ++ D V L
Sbjct: 207 NKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEAD---LNAKDREGDTPLHDAVRLN 263
Query: 882 IIDLI 886
+I
Sbjct: 264 RYKMI 268
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/119 (27%), Positives = 62/119 (52%), Gaps = 6/119 (5%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A++ K +VE L + + D + +ALH A GH ++ L+ +GA I +++ +
Sbjct: 127 AALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLE 186
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLI 617
+T +H A G+L +K ++ + G K I+ ++ +T LH+A + G+ A LI
Sbjct: 187 STAIHWASRGGNLDVLKLLL----NKGAK--ISARDKLLSTALHVAVRTGHYECAEHLI 239
Score = 45.6 bits (103), Expect = 8e-04
Identities = 25/85 (29%), Positives = 44/85 (51%)
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
++ N + ++ +T LH A + ++ L++ GA I D+ +T +H AS GN+
Sbjct: 142 DKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDV 201
Query: 850 AKILLSYNPDITLLNATEKTALAVA 874
K+LL+ I+ + TAL VA
Sbjct: 202 LKLLLNKGAKISARDKLLSTALHVA 226
Score = 44.0 bits (99), Expect = 0.002
Identities = 26/83 (31%), Positives = 43/83 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+++RD TALHVA G E L+ +++NA D + LH A ++ +L
Sbjct: 212 ISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLL 271
Query: 545 LHSGANINQKNIDKNTPLHLAVN 567
+ GA++N KN TP+ L ++
Sbjct: 272 IMYGADLNIKNCAGKTPMDLVLH 294
Score = 35.5 bits (78), Expect = 0.84
Identities = 23/85 (27%), Positives = 38/85 (44%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA+ NK V+ L + N + D + T LH A G++ + L+ I + E
Sbjct: 127 AALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLE 186
Query: 868 KTALAVAKDKVHLTIIDLIDNYANK 892
TA+ A +L ++ L+ N K
Sbjct: 187 STAIHWASRGGNLDVLKLLLNKGAK 211
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Query: 749 CKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHL 807
C +C + D+N D G T LH A R + +LI A++N +N +TP+ L
Sbjct: 234 CAEHLIAC-EADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDL 291
>BC018667-1|AAH18667.1| 319|Homo sapiens ankyrin repeat domain 1
(cardiac muscle) protein.
Length = 319
Score = 96.3 bits (229), Expect = 4e-19
Identities = 53/147 (36%), Positives = 86/147 (58%), Gaps = 6/147 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D + TALH A + G IVE L+E G++I D+ E +A+H+AS G+ +VL +LL+ G
Sbjct: 150 DEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKG 209
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A I+ ++ +T LH+AV GH C + +I + ++N + G+TPLH A +
Sbjct: 210 AKISARDKLLSTALHVAVRTGHYECAEHLI------ACEADLNAKDREGDTPLHDAVRLN 263
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFD 635
+ RLLI +G++ +++N KT D
Sbjct: 264 RYKMIRLLIMYGADLNIKNCAGKTPMD 290
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/121 (34%), Positives = 62/121 (51%), Gaps = 8/121 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
RD TA+H AS G +++ LL G++I+A D +ALH A GH L+
Sbjct: 182 RDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIAC 241
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKINI-NCANESGNTPLHLASK 606
A++N K+ + +TPLH AV ++ +I + G +NI NCA G TP+ L
Sbjct: 242 EADLNAKDREGDTPLHDAVRLNRYKMIRLLIMY----GADLNIKNCA---GKTPMDLVLH 294
Query: 607 W 607
W
Sbjct: 295 W 295
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/102 (30%), Positives = 51/102 (50%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TA+H+A+R G + +L+ A ++ R+K T LH+A L+ A++NA
Sbjct: 188 TAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNA 247
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
D +TPLHDA ++L+ Y D+ + N KT +
Sbjct: 248 KDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPM 289
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/125 (32%), Positives = 58/125 (46%), Gaps = 3/125 (2%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
+VCD TALH A G L+ A + R+ T +H A+ V++LLL
Sbjct: 147 DVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLL 206
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ GA I+A D +T LH A TG+ A+ L++ D LNA ++ D V L
Sbjct: 207 NKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEAD---LNAKDREGDTPLHDAVRLN 263
Query: 882 IIDLI 886
+I
Sbjct: 264 RYKMI 268
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/119 (27%), Positives = 62/119 (52%), Gaps = 6/119 (5%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A++ K +VE L + + D + +ALH A GH ++ L+ +GA I +++ +
Sbjct: 127 AALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLE 186
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLI 617
+T +H A G+L +K ++ + G K I+ ++ +T LH+A + G+ A LI
Sbjct: 187 STAIHWASRGGNLDVLKLLL----NKGAK--ISARDKLLSTALHVAVRTGHYECAEHLI 239
Score = 45.6 bits (103), Expect = 8e-04
Identities = 25/85 (29%), Positives = 44/85 (51%)
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
++ N + ++ +T LH A + ++ L++ GA I D+ +T +H AS GN+
Sbjct: 142 DKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDV 201
Query: 850 AKILLSYNPDITLLNATEKTALAVA 874
K+LL+ I+ + TAL VA
Sbjct: 202 LKLLLNKGAKISARDKLLSTALHVA 226
Score = 44.0 bits (99), Expect = 0.002
Identities = 26/83 (31%), Positives = 43/83 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+++RD TALHVA G E L+ +++NA D + LH A ++ +L
Sbjct: 212 ISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLL 271
Query: 545 LHSGANINQKNIDKNTPLHLAVN 567
+ GA++N KN TP+ L ++
Sbjct: 272 IMYGADLNIKNCAGKTPMDLVLH 294
Score = 35.5 bits (78), Expect = 0.84
Identities = 23/85 (27%), Positives = 38/85 (44%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA+ NK V+ L + N + D + T LH A G++ + L+ I + E
Sbjct: 127 AALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLE 186
Query: 868 KTALAVAKDKVHLTIIDLIDNYANK 892
TA+ A +L ++ L+ N K
Sbjct: 187 STAIHWASRGGNLDVLKLLLNKGAK 211
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Query: 749 CKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHL 807
C +C + D+N D G T LH A R + +LI A++N +N +TP+ L
Sbjct: 234 CAEHLIAC-EADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDL 291
>AY903446-1|AAX23581.1| 319|Homo sapiens liver ankyrin repeat
domain 1 protein.
Length = 319
Score = 96.3 bits (229), Expect = 4e-19
Identities = 53/147 (36%), Positives = 86/147 (58%), Gaps = 6/147 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D + TALH A + G IVE L+E G++I D+ E +A+H+AS G+ +VL +LL+ G
Sbjct: 150 DEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKG 209
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A I+ ++ +T LH+AV GH C + +I + ++N + G+TPLH A +
Sbjct: 210 AKISARDKLLSTALHVAVRTGHYECAEHLI------ACEADLNAKDREGDTPLHDAVRLN 263
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFD 635
+ RLLI +G++ +++N KT D
Sbjct: 264 RYKMIRLLIMYGADLNIKNCAGKTPMD 290
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/121 (34%), Positives = 62/121 (51%), Gaps = 8/121 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
RD TA+H AS G +++ LL G++I+A D +ALH A GH L+
Sbjct: 182 RDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIAC 241
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKINI-NCANESGNTPLHLASK 606
A++N K+ + +TPLH AV ++ +I + G +NI NCA G TP+ L
Sbjct: 242 EADLNAKDREGDTPLHDAVRLNRYKMIRLLIMY----GADLNIKNCA---GKTPMDLVLH 294
Query: 607 W 607
W
Sbjct: 295 W 295
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/102 (30%), Positives = 51/102 (50%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TA+H+A+R G + +L+ A ++ R+K T LH+A L+ A++NA
Sbjct: 188 TAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNA 247
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
D +TPLHDA ++L+ Y D+ + N KT +
Sbjct: 248 KDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPM 289
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/125 (32%), Positives = 58/125 (46%), Gaps = 3/125 (2%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
+VCD TALH A G L+ A + R+ T +H A+ V++LLL
Sbjct: 147 DVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLL 206
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ GA I+A D +T LH A TG+ A+ L++ D LNA ++ D V L
Sbjct: 207 NKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEAD---LNAKDREGDTPLHDAVRLN 263
Query: 882 IIDLI 886
+I
Sbjct: 264 RYKMI 268
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/119 (27%), Positives = 62/119 (52%), Gaps = 6/119 (5%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A++ K +VE L + + D + +ALH A GH ++ L+ +GA I +++ +
Sbjct: 127 AALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLE 186
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLI 617
+T +H A G+L +K ++ + G K I+ ++ +T LH+A + G+ A LI
Sbjct: 187 STAIHWASRGGNLDVLKLLL----NKGAK--ISARDKLLSTALHVAVRTGHYECAEHLI 239
Score = 45.6 bits (103), Expect = 8e-04
Identities = 25/85 (29%), Positives = 44/85 (51%)
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
++ N + ++ +T LH A + ++ L++ GA I D+ +T +H AS GN+
Sbjct: 142 DKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDV 201
Query: 850 AKILLSYNPDITLLNATEKTALAVA 874
K+LL+ I+ + TAL VA
Sbjct: 202 LKLLLNKGAKISARDKLLSTALHVA 226
Score = 44.0 bits (99), Expect = 0.002
Identities = 26/83 (31%), Positives = 43/83 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+++RD TALHVA G E L+ +++NA D + LH A ++ +L
Sbjct: 212 ISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLL 271
Query: 545 LHSGANINQKNIDKNTPLHLAVN 567
+ GA++N KN TP+ L ++
Sbjct: 272 IMYGADLNIKNCAGKTPMDLVLH 294
Score = 35.5 bits (78), Expect = 0.84
Identities = 23/85 (27%), Positives = 38/85 (44%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA+ NK V+ L + N + D + T LH A G++ + L+ I + E
Sbjct: 127 AALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLE 186
Query: 868 KTALAVAKDKVHLTIIDLIDNYANK 892
TA+ A +L ++ L+ N K
Sbjct: 187 STAIHWASRGGNLDVLKLLLNKGAK 211
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Query: 749 CKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHL 807
C +C + D+N D G T LH A R + +LI A++N +N +TP+ L
Sbjct: 234 CAEHLIAC-EADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDL 291
>AL590622-4|CAC70101.1| 319|Homo sapiens ankyrin repeat domain 1
(cardiac muscle) protein.
Length = 319
Score = 96.3 bits (229), Expect = 4e-19
Identities = 53/147 (36%), Positives = 86/147 (58%), Gaps = 6/147 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D + TALH A + G IVE L+E G++I D+ E +A+H+AS G+ +VL +LL+ G
Sbjct: 150 DEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKG 209
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A I+ ++ +T LH+AV GH C + +I + ++N + G+TPLH A +
Sbjct: 210 AKISARDKLLSTALHVAVRTGHYECAEHLI------ACEADLNAKDREGDTPLHDAVRLN 263
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFD 635
+ RLLI +G++ +++N KT D
Sbjct: 264 RYKMIRLLIMYGADLNIKNCAGKTPMD 290
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/121 (34%), Positives = 62/121 (51%), Gaps = 8/121 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
RD TA+H AS G +++ LL G++I+A D +ALH A GH L+
Sbjct: 182 RDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIAC 241
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKINI-NCANESGNTPLHLASK 606
A++N K+ + +TPLH AV ++ +I + G +NI NCA G TP+ L
Sbjct: 242 EADLNAKDREGDTPLHDAVRLNRYKMIRLLIMY----GADLNIKNCA---GKTPMDLVLH 294
Query: 607 W 607
W
Sbjct: 295 W 295
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/102 (30%), Positives = 51/102 (50%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TA+H+A+R G + +L+ A ++ R+K T LH+A L+ A++NA
Sbjct: 188 TAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNA 247
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
D +TPLHDA ++L+ Y D+ + N KT +
Sbjct: 248 KDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPM 289
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/125 (32%), Positives = 58/125 (46%), Gaps = 3/125 (2%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
+VCD TALH A G L+ A + R+ T +H A+ V++LLL
Sbjct: 147 DVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLL 206
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ GA I+A D +T LH A TG+ A+ L++ D LNA ++ D V L
Sbjct: 207 NKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEAD---LNAKDREGDTPLHDAVRLN 263
Query: 882 IIDLI 886
+I
Sbjct: 264 RYKMI 268
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/119 (27%), Positives = 62/119 (52%), Gaps = 6/119 (5%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A++ K +VE L + + D + +ALH A GH ++ L+ +GA I +++ +
Sbjct: 127 AALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLE 186
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLI 617
+T +H A G+L +K ++ + G K I+ ++ +T LH+A + G+ A LI
Sbjct: 187 STAIHWASRGGNLDVLKLLL----NKGAK--ISARDKLLSTALHVAVRTGHYECAEHLI 239
Score = 45.6 bits (103), Expect = 8e-04
Identities = 25/85 (29%), Positives = 44/85 (51%)
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
++ N + ++ +T LH A + ++ L++ GA I D+ +T +H AS GN+
Sbjct: 142 DKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDV 201
Query: 850 AKILLSYNPDITLLNATEKTALAVA 874
K+LL+ I+ + TAL VA
Sbjct: 202 LKLLLNKGAKISARDKLLSTALHVA 226
Score = 44.0 bits (99), Expect = 0.002
Identities = 26/83 (31%), Positives = 43/83 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+++RD TALHVA G E L+ +++NA D + LH A ++ +L
Sbjct: 212 ISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLL 271
Query: 545 LHSGANINQKNIDKNTPLHLAVN 567
+ GA++N KN TP+ L ++
Sbjct: 272 IMYGADLNIKNCAGKTPMDLVLH 294
Score = 35.5 bits (78), Expect = 0.84
Identities = 23/85 (27%), Positives = 38/85 (44%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA+ NK V+ L + N + D + T LH A G++ + L+ I + E
Sbjct: 127 AALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLE 186
Query: 868 KTALAVAKDKVHLTIIDLIDNYANK 892
TA+ A +L ++ L+ N K
Sbjct: 187 STAIHWASRGGNLDVLKLLLNKGAK 211
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Query: 749 CKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHL 807
C +C + D+N D G T LH A R + +LI A++N +N +TP+ L
Sbjct: 234 CAEHLIAC-EADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDL 291
>BC112351-1|AAI12352.1| 725|Homo sapiens INVS protein protein.
Length = 725
Score = 95.5 bits (227), Expect = 7e-19
Identities = 85/384 (22%), Positives = 168/384 (43%), Gaps = 16/384 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L + + + LL+ G+++N TD ++ +ALH A+ +G+ + +LL
Sbjct: 45 DQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR 104
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN QK++++ TPLHL + C+ ++ F ++ +++ T LH ++ +
Sbjct: 105 ANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYN 160
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+LLI+H S + + K +A N + + T T S +
Sbjct: 161 NPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQD 218
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR-----AISYGDVKLACFYMNI 723
E P + + + D + ++ N+ + + R A G ++ +
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLER 277
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDE 782
+ S I D + + L H + + + V + D G T+ +AA G D+
Sbjct: 278 NKSGTIPSDSQGATPL-HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDD 336
Query: 783 FCNILIFNRA--NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
++ ++ ++N +K T LH AA++ ++LLL+N A ++A DV ++TPL
Sbjct: 337 VLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFR 396
Query: 841 ASETGNIGAAKILLSYNPDITLLN 864
A E G+ + L+ + L++
Sbjct: 397 ACEMGHKDVIQTLIKGGARVDLVD 420
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 467
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 468 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIK 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 144 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 203
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 258
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 309
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 310 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 364
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 365 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 422
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 423 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 482
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 483 NIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 110 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 169
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 170 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 229
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 230 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 280
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 281 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 340
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 341 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 399
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA 512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 480 ADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 535
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 536 RHEVIQFMLEHGA 548
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 392 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 451
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDKEGRTALHWSCNNGYLDAI 505
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 506 KLLLDFAAFPNQMENNEERYTPLDYA 531
Score = 58.8 bits (136), Expect = 8e-08
Identities = 90/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 179 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 238
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 239 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 293
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 352
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 353 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 408
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 466
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++K+ +T LH + N I+LLLD A N ++ R T
Sbjct: 467 GYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
Query: 837 PL 838
PL
Sbjct: 527 PL 528
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 132
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 133 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 248 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 308 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 363
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 364 AALSGHVSTVKLLLENNAQ 382
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 512 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 551
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 481 DPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 540
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 541 QFMLEHGALSIAAIQDIA 558
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/86 (26%), Positives = 43/86 (50%)
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+++ N A + ++ +TPL + ++ LL GA++N D ++ T LH A++ G
Sbjct: 33 LIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKG 92
Query: 846 NIGAAKILLSYNPDITLLNATEKTAL 871
N K+LL+ + + E T L
Sbjct: 93 NYRFMKLLLTRRANWMQKDLEEMTPL 118
Score = 33.5 bits (73), Expect = 3.4
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 805 LHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
+H AA+N +K + RL++ N A + D TPL + A LL D+
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 864 NATEKTALAVAKDKVHLTIIDLI 886
+ +++TAL +A K + + L+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLL 100
>BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a
protein.
Length = 1065
Score = 95.5 bits (227), Expect = 7e-19
Identities = 85/384 (22%), Positives = 168/384 (43%), Gaps = 16/384 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L + + + LL+ G+++N TD ++ +ALH A+ +G+ + +LL
Sbjct: 45 DQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR 104
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN QK++++ TPLHL + C+ ++ F ++ +++ T LH ++ +
Sbjct: 105 ANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYN 160
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+LLI+H S + + K +A N + + T T S +
Sbjct: 161 NPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQD 218
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR-----AISYGDVKLACFYMNI 723
E P + + + D + ++ N+ + + R A G ++ +
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLER 277
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDE 782
+ S I D + + L H + + + V + D G T+ +AA G D+
Sbjct: 278 NKSGTIPSDSQGATPL-HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDD 336
Query: 783 FCNILIFNRA--NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
++ ++ ++N +K T LH AA++ ++LLL+N A ++A DV ++TPL
Sbjct: 337 VLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFR 396
Query: 841 ASETGNIGAAKILLSYNPDITLLN 864
A E G+ + L+ + L++
Sbjct: 397 ACEMGHKDVIQTLIKGGARVDLVD 420
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 467
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 468 YINCMAVLMENNADPNIQDQEGRTALHWSCNNGYLDAIK 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 144 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 203
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 258
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 309
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 310 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 364
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 365 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 422
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 423 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 482
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 483 NIQDQEGRTALHWSCNNGYLDAIKLLLDF 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 110 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 169
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 170 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 229
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 230 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 280
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 281 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 340
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 341 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 399
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDQEGRTALHWSCNNGYLDAIKLLLDFA 512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 480 ADPNIQDQEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 535
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 536 RHEVIQFMLEHGA 548
Score = 60.9 bits (141), Expect = 2e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 392 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 451
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDQEGRTALHWSCNNGYLDAI 505
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 506 KLLLDFAAFPNQMENNEERYTPLDYA 531
Score = 57.2 bits (132), Expect = 2e-07
Identities = 89/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 179 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 238
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 239 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 293
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 352
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 353 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 408
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 466
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++++ +T LH + N I+LLLD A N ++ R T
Sbjct: 467 GYINCMAVLMENNADPNIQDQEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
Query: 837 PL 838
PL
Sbjct: 527 PL 528
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 132
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 133 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 248 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 308 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 363
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 364 AALSGHVSTVKLLLENNAQ 382
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDQEGRTALHWSCNNGYLDAIKLLLDF 511
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 512 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 551
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 481 DPNIQDQEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 540
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 541 QFMLEHGALSIAAIQDIA 558
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/86 (26%), Positives = 43/86 (50%)
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+++ N A + ++ +TPL + ++ LL GA++N D ++ T LH A++ G
Sbjct: 33 LIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKG 92
Query: 846 NIGAAKILLSYNPDITLLNATEKTAL 871
N K+LL+ + + E T L
Sbjct: 93 NYRFMKLLLTRRANWMQKDLEEMTPL 118
Score = 33.5 bits (73), Expect = 3.4
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 805 LHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
+H AA+N +K + RL++ N A + D TPL + A LL D+
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 864 NATEKTALAVAKDKVHLTIIDLI 886
+ +++TAL +A K + + L+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLL 100
>BC041665-1|AAH41665.1| 604|Homo sapiens Similar to inversin
protein.
Length = 604
Score = 95.5 bits (227), Expect = 7e-19
Identities = 85/384 (22%), Positives = 168/384 (43%), Gaps = 16/384 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L + + + LL+ G+++N TD ++ +ALH A+ +G+ + +LL
Sbjct: 45 DQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR 104
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN QK++++ TPLHL + C+ ++ F ++ +++ T LH ++ +
Sbjct: 105 ANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYN 160
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+LLI+H S + + K +A N + + T T S +
Sbjct: 161 NPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQD 218
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR-----AISYGDVKLACFYMNI 723
E P + + + D + ++ N+ + + R A G ++ +
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLER 277
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDE 782
+ S I D + + L H + + + V + D G T+ +AA G D+
Sbjct: 278 NKSGTIPSDSQGATPL-HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDD 336
Query: 783 FCNILIFNRA--NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
++ ++ ++N +K T LH AA++ ++LLL+N A ++A DV ++TPL
Sbjct: 337 VLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFR 396
Query: 841 ASETGNIGAAKILLSYNPDITLLN 864
A E G+ + L+ + L++
Sbjct: 397 ACEMGHKDVIQTLIKGGARVDLVD 420
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 467
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 468 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIK 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 144 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 203
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 258
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 309
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 310 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 364
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 365 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 422
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 423 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 482
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 483 NIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 110 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 169
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 170 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 229
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 230 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 280
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 281 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 340
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 341 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 399
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA 512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 480 ADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 535
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 536 RHEVIQFMLEHGA 548
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 392 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 451
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDKEGRTALHWSCNNGYLDAI 505
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 506 KLLLDFAAFPNQMENNEERYTPLDYA 531
Score = 58.8 bits (136), Expect = 8e-08
Identities = 90/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 179 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 238
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 239 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 293
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 352
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 353 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 408
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 466
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++K+ +T LH + N I+LLLD A N ++ R T
Sbjct: 467 GYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
Query: 837 PL 838
PL
Sbjct: 527 PL 528
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 132
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 133 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 248 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 308 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 363
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 364 AALSGHVSTVKLLLENNAQ 382
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 512 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 551
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 481 DPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 540
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 541 QFMLEHGALSIAAIQDIA 558
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/86 (26%), Positives = 43/86 (50%)
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+++ N A + ++ +TPL + ++ LL GA++N D ++ T LH A++ G
Sbjct: 33 LIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKG 92
Query: 846 NIGAAKILLSYNPDITLLNATEKTAL 871
N K+LL+ + + E T L
Sbjct: 93 NYRFMKLLLTRRANWMQKDLEEMTPL 118
Score = 33.5 bits (73), Expect = 3.4
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 805 LHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
+H AA+N +K + RL++ N A + D TPL + A LL D+
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 864 NATEKTALAVAKDKVHLTIIDLI 886
+ +++TAL +A K + + L+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLL 100
>AL445214-4|CAI39744.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 95.5 bits (227), Expect = 7e-19
Identities = 85/384 (22%), Positives = 168/384 (43%), Gaps = 16/384 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L + + + LL+ G+++N TD ++ +ALH A+ +G+ + +LL
Sbjct: 45 DQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR 104
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN QK++++ TPLHL + C+ ++ F ++ +++ T LH ++ +
Sbjct: 105 ANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYN 160
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+LLI+H S + + K +A N + + T T S +
Sbjct: 161 NPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQD 218
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR-----AISYGDVKLACFYMNI 723
E P + + + D + ++ N+ + + R A G ++ +
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLER 277
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDE 782
+ S I D + + L H + + + V + D G T+ +AA G D+
Sbjct: 278 NKSGTIPSDSQGATPL-HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDD 336
Query: 783 FCNILIFNRA--NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
++ ++ ++N +K T LH AA++ ++LLL+N A ++A DV ++TPL
Sbjct: 337 VLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFR 396
Query: 841 ASETGNIGAAKILLSYNPDITLLN 864
A E G+ + L+ + L++
Sbjct: 397 ACEMGHKDVIQTLIKGGARVDLVD 420
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 467
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 468 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIK 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 144 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 203
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 258
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 309
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 310 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 364
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 365 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 422
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 423 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 482
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 483 NIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 110 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 169
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 170 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 229
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 230 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 280
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 281 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 340
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 341 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 399
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA 512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 480 ADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 535
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 536 RHEVIQFMLEHGA 548
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 392 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 451
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDKEGRTALHWSCNNGYLDAI 505
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 506 KLLLDFAAFPNQMENNEERYTPLDYA 531
Score = 58.8 bits (136), Expect = 8e-08
Identities = 90/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 179 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 238
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 239 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 293
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 352
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 353 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 408
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 466
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++K+ +T LH + N I+LLLD A N ++ R T
Sbjct: 467 GYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
Query: 837 PL 838
PL
Sbjct: 527 PL 528
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 132
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 133 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 248 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 308 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 363
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 364 AALSGHVSTVKLLLENNAQ 382
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 512 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 551
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 481 DPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 540
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 541 QFMLEHGALSIAAIQDIA 558
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/86 (26%), Positives = 43/86 (50%)
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+++ N A + ++ +TPL + ++ LL GA++N D ++ T LH A++ G
Sbjct: 33 LIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKG 92
Query: 846 NIGAAKILLSYNPDITLLNATEKTAL 871
N K+LL+ + + E T L
Sbjct: 93 NYRFMKLLLTRRANWMQKDLEEMTPL 118
Score = 33.5 bits (73), Expect = 3.4
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 805 LHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
+H AA+N +K + RL++ N A + D TPL + A LL D+
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 864 NATEKTALAVAKDKVHLTIIDLI 886
+ +++TAL +A K + + L+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLL 100
>AL445214-3|CAI39745.2| 895|Homo sapiens inversin protein.
Length = 895
Score = 95.5 bits (227), Expect = 7e-19
Identities = 85/384 (22%), Positives = 168/384 (43%), Gaps = 16/384 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L + + + LL+ G+++N TD ++ +ALH A+ +G+ + +LL
Sbjct: 45 DQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR 104
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN QK++++ TPLHL + C+ ++ F ++ +++ T LH ++ +
Sbjct: 105 ANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYN 160
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+LLI+H S + + K +A N + + T T S +
Sbjct: 161 NPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQD 218
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR-----AISYGDVKLACFYMNI 723
E P + + + D + ++ N+ + + R A G ++ +
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLER 277
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDE 782
+ S I D + + L H + + + V + D G T+ +AA G D+
Sbjct: 278 NKSGTIPSDSQGATPL-HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDD 336
Query: 783 FCNILIFNRA--NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
++ ++ ++N +K T LH AA++ ++LLL+N A ++A DV ++TPL
Sbjct: 337 VLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFR 396
Query: 841 ASETGNIGAAKILLSYNPDITLLN 864
A E G+ + L+ + L++
Sbjct: 397 ACEMGHKDVIQTLIKGGARVDLVD 420
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 467
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 468 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIK 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 144 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 203
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 258
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 309
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 310 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 364
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 365 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 422
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 423 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 482
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 483 NIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 110 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 169
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 170 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 229
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 230 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 280
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 281 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 340
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 341 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 399
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA 512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 480 ADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 535
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 536 RHEVIQFMLEHGA 548
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 392 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 451
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDKEGRTALHWSCNNGYLDAI 505
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 506 KLLLDFAAFPNQMENNEERYTPLDYA 531
Score = 58.8 bits (136), Expect = 8e-08
Identities = 90/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 179 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 238
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 239 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 293
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 352
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 353 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 408
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 466
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++K+ +T LH + N I+LLLD A N ++ R T
Sbjct: 467 GYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
Query: 837 PL 838
PL
Sbjct: 527 PL 528
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 132
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 133 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 248 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 308 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 363
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 364 AALSGHVSTVKLLLENNAQ 382
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 512 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 551
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 481 DPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 540
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 541 QFMLEHGALSIAAIQDIA 558
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/86 (26%), Positives = 43/86 (50%)
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+++ N A + ++ +TPL + ++ LL GA++N D ++ T LH A++ G
Sbjct: 33 LIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKG 92
Query: 846 NIGAAKILLSYNPDITLLNATEKTAL 871
N K+LL+ + + E T L
Sbjct: 93 NYRFMKLLLTRRANWMQKDLEEMTPL 118
Score = 33.5 bits (73), Expect = 3.4
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 805 LHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
+H AA+N +K + RL++ N A + D TPL + A LL D+
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 864 NATEKTALAVAKDKVHLTIIDLI 886
+ +++TAL +A K + + L+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLL 100
>AL356798-2|CAI40807.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 95.5 bits (227), Expect = 7e-19
Identities = 85/384 (22%), Positives = 168/384 (43%), Gaps = 16/384 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L + + + LL+ G+++N TD ++ +ALH A+ +G+ + +LL
Sbjct: 45 DQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR 104
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN QK++++ TPLHL + C+ ++ F ++ +++ T LH ++ +
Sbjct: 105 ANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYN 160
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+LLI+H S + + K +A N + + T T S +
Sbjct: 161 NPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQD 218
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR-----AISYGDVKLACFYMNI 723
E P + + + D + ++ N+ + + R A G ++ +
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLER 277
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDE 782
+ S I D + + L H + + + V + D G T+ +AA G D+
Sbjct: 278 NKSGTIPSDSQGATPL-HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDD 336
Query: 783 FCNILIFNRA--NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
++ ++ ++N +K T LH AA++ ++LLL+N A ++A DV ++TPL
Sbjct: 337 VLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFR 396
Query: 841 ASETGNIGAAKILLSYNPDITLLN 864
A E G+ + L+ + L++
Sbjct: 397 ACEMGHKDVIQTLIKGGARVDLVD 420
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 467
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 468 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIK 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 144 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 203
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 258
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 309
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 310 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 364
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 365 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 422
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 423 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 482
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 483 NIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 110 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 169
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 170 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 229
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 230 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 280
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 281 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 340
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 341 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 399
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA 512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 480 ADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 535
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 536 RHEVIQFMLEHGA 548
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 392 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 451
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDKEGRTALHWSCNNGYLDAI 505
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 506 KLLLDFAAFPNQMENNEERYTPLDYA 531
Score = 58.8 bits (136), Expect = 8e-08
Identities = 90/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 179 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 238
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 239 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 293
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 352
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 353 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 408
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 466
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++K+ +T LH + N I+LLLD A N ++ R T
Sbjct: 467 GYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
Query: 837 PL 838
PL
Sbjct: 527 PL 528
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 132
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 133 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 248 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 308 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 363
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 364 AALSGHVSTVKLLLENNAQ 382
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 512 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 551
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 481 DPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 540
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 541 QFMLEHGALSIAAIQDIA 558
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/86 (26%), Positives = 43/86 (50%)
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+++ N A + ++ +TPL + ++ LL GA++N D ++ T LH A++ G
Sbjct: 33 LIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKG 92
Query: 846 NIGAAKILLSYNPDITLLNATEKTAL 871
N K+LL+ + + E T L
Sbjct: 93 NYRFMKLLLTRRANWMQKDLEEMTPL 118
Score = 33.5 bits (73), Expect = 3.4
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 805 LHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
+H AA+N +K + RL++ N A + D TPL + A LL D+
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 864 NATEKTALAVAKDKVHLTIIDLI 886
+ +++TAL +A K + + L+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLL 100
>AL356798-1|CAI40808.2| 895|Homo sapiens inversin protein.
Length = 895
Score = 95.5 bits (227), Expect = 7e-19
Identities = 85/384 (22%), Positives = 168/384 (43%), Gaps = 16/384 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L + + + LL+ G+++N TD ++ +ALH A+ +G+ + +LL
Sbjct: 45 DQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR 104
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN QK++++ TPLHL + C+ ++ F ++ +++ T LH ++ +
Sbjct: 105 ANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYN 160
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+LLI+H S + + K +A N + + T T S +
Sbjct: 161 NPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQD 218
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR-----AISYGDVKLACFYMNI 723
E P + + + D + ++ N+ + + R A G ++ +
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLER 277
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDE 782
+ S I D + + L H + + + V + D G T+ +AA G D+
Sbjct: 278 NKSGTIPSDSQGATPL-HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDD 336
Query: 783 FCNILIFNRA--NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
++ ++ ++N +K T LH AA++ ++LLL+N A ++A DV ++TPL
Sbjct: 337 VLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFR 396
Query: 841 ASETGNIGAAKILLSYNPDITLLN 864
A E G+ + L+ + L++
Sbjct: 397 ACEMGHKDVIQTLIKGGARVDLVD 420
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 467
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 468 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIK 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 144 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 203
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 258
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 309
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 310 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 364
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 365 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 422
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 423 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 482
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 483 NIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 110 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 169
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 170 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 229
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 230 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 280
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 281 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 340
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 341 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 399
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA 512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 480 ADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 535
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 536 RHEVIQFMLEHGA 548
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 392 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 451
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDKEGRTALHWSCNNGYLDAI 505
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 506 KLLLDFAAFPNQMENNEERYTPLDYA 531
Score = 58.8 bits (136), Expect = 8e-08
Identities = 90/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 179 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 238
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 239 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 293
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 352
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 353 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 408
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 466
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++K+ +T LH + N I+LLLD A N ++ R T
Sbjct: 467 GYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
Query: 837 PL 838
PL
Sbjct: 527 PL 528
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 132
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 133 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 248 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 308 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 363
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 364 AALSGHVSTVKLLLENNAQ 382
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 512 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 551
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 481 DPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 540
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 541 QFMLEHGALSIAAIQDIA 558
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/86 (26%), Positives = 43/86 (50%)
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+++ N A + ++ +TPL + ++ LL GA++N D ++ T LH A++ G
Sbjct: 33 LIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKG 92
Query: 846 NIGAAKILLSYNPDITLLNATEKTAL 871
N K+LL+ + + E T L
Sbjct: 93 NYRFMKLLLTRRANWMQKDLEEMTPL 118
Score = 33.5 bits (73), Expect = 3.4
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 805 LHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
+H AA+N +K + RL++ N A + D TPL + A LL D+
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 864 NATEKTALAVAKDKVHLTIIDLI 886
+ +++TAL +A K + + L+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLL 100
>AL137072-3|CAH72173.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 95.5 bits (227), Expect = 7e-19
Identities = 85/384 (22%), Positives = 168/384 (43%), Gaps = 16/384 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L + + + LL+ G+++N TD ++ +ALH A+ +G+ + +LL
Sbjct: 45 DQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR 104
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN QK++++ TPLHL + C+ ++ F ++ +++ T LH ++ +
Sbjct: 105 ANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYN 160
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+LLI+H S + + K +A N + + T T S +
Sbjct: 161 NPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQD 218
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR-----AISYGDVKLACFYMNI 723
E P + + + D + ++ N+ + + R A G ++ +
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLER 277
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDE 782
+ S I D + + L H + + + V + D G T+ +AA G D+
Sbjct: 278 NKSGTIPSDSQGATPL-HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDD 336
Query: 783 FCNILIFNRA--NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
++ ++ ++N +K T LH AA++ ++LLL+N A ++A DV ++TPL
Sbjct: 337 VLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFR 396
Query: 841 ASETGNIGAAKILLSYNPDITLLN 864
A E G+ + L+ + L++
Sbjct: 397 ACEMGHKDVIQTLIKGGARVDLVD 420
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 467
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 468 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIK 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 144 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 203
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 258
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 309
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 310 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 364
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 365 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 422
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 423 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 482
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 483 NIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 110 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 169
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 170 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 229
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 230 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 280
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 281 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 340
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 341 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 399
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA 512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 480 ADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 535
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 536 RHEVIQFMLEHGA 548
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 392 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 451
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDKEGRTALHWSCNNGYLDAI 505
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 506 KLLLDFAAFPNQMENNEERYTPLDYA 531
Score = 58.8 bits (136), Expect = 8e-08
Identities = 90/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 179 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 238
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 239 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 293
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 352
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 353 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 408
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 466
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++K+ +T LH + N I+LLLD A N ++ R T
Sbjct: 467 GYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
Query: 837 PL 838
PL
Sbjct: 527 PL 528
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 132
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 133 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 248 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 308 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 363
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 364 AALSGHVSTVKLLLENNAQ 382
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 512 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 551
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 481 DPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 540
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 541 QFMLEHGALSIAAIQDIA 558
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/86 (26%), Positives = 43/86 (50%)
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+++ N A + ++ +TPL + ++ LL GA++N D ++ T LH A++ G
Sbjct: 33 LIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKG 92
Query: 846 NIGAAKILLSYNPDITLLNATEKTAL 871
N K+LL+ + + E T L
Sbjct: 93 NYRFMKLLLTRRANWMQKDLEEMTPL 118
Score = 33.5 bits (73), Expect = 3.4
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 805 LHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
+H AA+N +K + RL++ N A + D TPL + A LL D+
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 864 NATEKTALAVAKDKVHLTIIDLI 886
+ +++TAL +A K + + L+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLL 100
>AL137072-2|CAM16212.1| 895|Homo sapiens inversin protein.
Length = 895
Score = 95.5 bits (227), Expect = 7e-19
Identities = 85/384 (22%), Positives = 168/384 (43%), Gaps = 16/384 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L + + + LL+ G+++N TD ++ +ALH A+ +G+ + +LL
Sbjct: 45 DQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR 104
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN QK++++ TPLHL + C+ ++ F ++ +++ T LH ++ +
Sbjct: 105 ANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYN 160
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+LLI+H S + + K +A N + + T T S +
Sbjct: 161 NPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQD 218
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR-----AISYGDVKLACFYMNI 723
E P + + + D + ++ N+ + + R A G ++ +
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLER 277
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDE 782
+ S I D + + L H + + + V + D G T+ +AA G D+
Sbjct: 278 NKSGTIPSDSQGATPL-HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDD 336
Query: 783 FCNILIFNRA--NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
++ ++ ++N +K T LH AA++ ++LLL+N A ++A DV ++TPL
Sbjct: 337 VLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFR 396
Query: 841 ASETGNIGAAKILLSYNPDITLLN 864
A E G+ + L+ + L++
Sbjct: 397 ACEMGHKDVIQTLIKGGARVDLVD 420
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 467
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 468 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIK 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 144 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 203
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 258
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 309
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 310 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 364
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 365 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 422
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 423 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 482
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 483 NIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 110 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 169
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 170 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 229
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 230 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 280
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 281 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 340
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 341 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 399
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA 512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 480 ADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 535
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 536 RHEVIQFMLEHGA 548
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 392 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 451
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDKEGRTALHWSCNNGYLDAI 505
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 506 KLLLDFAAFPNQMENNEERYTPLDYA 531
Score = 58.8 bits (136), Expect = 8e-08
Identities = 90/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 179 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 238
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 239 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 293
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 352
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 353 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 408
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 466
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++K+ +T LH + N I+LLLD A N ++ R T
Sbjct: 467 GYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
Query: 837 PL 838
PL
Sbjct: 527 PL 528
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 132
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 133 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 248 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 308 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 363
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 364 AALSGHVSTVKLLLENNAQ 382
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 512 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 551
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 481 DPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 540
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 541 QFMLEHGALSIAAIQDIA 558
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/86 (26%), Positives = 43/86 (50%)
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+++ N A + ++ +TPL + ++ LL GA++N D ++ T LH A++ G
Sbjct: 33 LIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKG 92
Query: 846 NIGAAKILLSYNPDITLLNATEKTAL 871
N K+LL+ + + E T L
Sbjct: 93 NYRFMKLLLTRRANWMQKDLEEMTPL 118
Score = 33.5 bits (73), Expect = 3.4
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 805 LHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
+H AA+N +K + RL++ N A + D TPL + A LL D+
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 864 NATEKTALAVAKDKVHLTIIDLI 886
+ +++TAL +A K + + L+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLL 100
>AF084382-2|AAC79457.1| 895|Homo sapiens inversin protein
alternative isoform protein.
Length = 895
Score = 95.5 bits (227), Expect = 7e-19
Identities = 85/384 (22%), Positives = 168/384 (43%), Gaps = 16/384 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L + + + LL+ G+++N TD ++ +ALH A+ +G+ + +LL
Sbjct: 45 DQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR 104
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN QK++++ TPLHL + C+ ++ F ++ +++ T LH ++ +
Sbjct: 105 ANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYN 160
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+LLI+H S + + K +A N + + T T S +
Sbjct: 161 NPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQD 218
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR-----AISYGDVKLACFYMNI 723
E P + + + D + ++ N+ + + R A G ++ +
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLER 277
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDE 782
+ S I D + + L H + + + V + D G T+ +AA G D+
Sbjct: 278 NKSGTIPSDSQGATPL-HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDD 336
Query: 783 FCNILIFNRA--NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
++ ++ ++N +K T LH AA++ ++LLL+N A ++A DV ++TPL
Sbjct: 337 VLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFR 396
Query: 841 ASETGNIGAAKILLSYNPDITLLN 864
A E G+ + L+ + L++
Sbjct: 397 ACEMGHKDVIQTLIKGGARVDLVD 420
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 467
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 468 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIK 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 144 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 203
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 258
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 309
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 310 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 364
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 365 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 422
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 423 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 482
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 483 NIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 110 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 169
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 170 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 229
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 230 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 280
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 281 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 340
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 341 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 399
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA 512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 480 ADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 535
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 536 RHEVIQFMLEHGA 548
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 392 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 451
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDKEGRTALHWSCNNGYLDAI 505
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 506 KLLLDFAAFPNQMENNEERYTPLDYA 531
Score = 58.8 bits (136), Expect = 8e-08
Identities = 90/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 179 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 238
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 239 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 293
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 352
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 353 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 408
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 466
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++K+ +T LH + N I+LLLD A N ++ R T
Sbjct: 467 GYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
Query: 837 PL 838
PL
Sbjct: 527 PL 528
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 132
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 133 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 248 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 308 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 363
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 364 AALSGHVSTVKLLLENNAQ 382
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 512 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 551
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 481 DPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 540
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 541 QFMLEHGALSIAAIQDIA 558
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/86 (26%), Positives = 43/86 (50%)
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+++ N A + ++ +TPL + ++ LL GA++N D ++ T LH A++ G
Sbjct: 33 LIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKG 92
Query: 846 NIGAAKILLSYNPDITLLNATEKTAL 871
N K+LL+ + + E T L
Sbjct: 93 NYRFMKLLLTRRANWMQKDLEEMTPL 118
Score = 33.5 bits (73), Expect = 3.4
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 805 LHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
+H AA+N +K + RL++ N A + D TPL + A LL D+
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 864 NATEKTALAVAKDKVHLTIIDLI 886
+ +++TAL +A K + + L+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLL 100
>AF084382-1|AAC79456.1| 1065|Homo sapiens inversin protein protein.
Length = 1065
Score = 95.5 bits (227), Expect = 7e-19
Identities = 85/384 (22%), Positives = 168/384 (43%), Gaps = 16/384 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L + + + LL+ G+++N TD ++ +ALH A+ +G+ + +LL
Sbjct: 45 DQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR 104
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN QK++++ TPLHL + C+ ++ F ++ +++ T LH ++ +
Sbjct: 105 ANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYN 160
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+LLI+H S + + K +A N + + T T S +
Sbjct: 161 NPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQD 218
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR-----AISYGDVKLACFYMNI 723
E P + + + D + ++ N+ + + R A G ++ +
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLER 277
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDE 782
+ S I D + + L H + + + V + D G T+ +AA G D+
Sbjct: 278 NKSGTIPSDSQGATPL-HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDD 336
Query: 783 FCNILIFNRA--NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
++ ++ ++N +K T LH AA++ ++LLL+N A ++A DV ++TPL
Sbjct: 337 VLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFR 396
Query: 841 ASETGNIGAAKILLSYNPDITLLN 864
A E G+ + L+ + L++
Sbjct: 397 ACEMGHKDVIQTLIKGGARVDLVD 420
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 467
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 468 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIK 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 144 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 203
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 258
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 309
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 310 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 364
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 365 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 422
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 423 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 482
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 483 NIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 110 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 169
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 170 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 229
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 230 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 280
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 281 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 340
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 341 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 399
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA 512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 480 ADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 535
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 536 RHEVIQFMLEHGA 548
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 392 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 451
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDKEGRTALHWSCNNGYLDAI 505
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 506 KLLLDFAAFPNQMENNEERYTPLDYA 531
Score = 58.8 bits (136), Expect = 8e-08
Identities = 90/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 179 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 238
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 239 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 293
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 352
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 353 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 408
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 466
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++K+ +T LH + N I+LLLD A N ++ R T
Sbjct: 467 GYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
Query: 837 PL 838
PL
Sbjct: 527 PL 528
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 132
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 133 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 248 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 308 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 363
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 364 AALSGHVSTVKLLLENNAQ 382
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 512 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 551
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 481 DPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 540
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 541 QFMLEHGALSIAAIQDIA 558
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/86 (26%), Positives = 43/86 (50%)
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+++ N A + ++ +TPL + ++ LL GA++N D ++ T LH A++ G
Sbjct: 33 LIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKG 92
Query: 846 NIGAAKILLSYNPDITLLNATEKTAL 871
N K+LL+ + + E T L
Sbjct: 93 NYRFMKLLLTRRANWMQKDLEEMTPL 118
Score = 33.5 bits (73), Expect = 3.4
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 805 LHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
+H AA+N +K + RL++ N A + D TPL + A LL D+
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 864 NATEKTALAVAKDKVHLTIIDLI 886
+ +++TAL +A K + + L+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLL 100
>AF084367-1|AAC79436.1| 1065|Homo sapiens inversin protein protein.
Length = 1065
Score = 95.5 bits (227), Expect = 7e-19
Identities = 85/384 (22%), Positives = 168/384 (43%), Gaps = 16/384 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L + + + LL+ G+++N TD ++ +ALH A+ +G+ + +LL
Sbjct: 45 DQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR 104
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN QK++++ TPLHL + C+ ++ F ++ +++ T LH ++ +
Sbjct: 105 ANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYN 160
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS 668
+LLI+H S + + K +A N + + T T S +
Sbjct: 161 NPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQD 218
Query: 669 CESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR-----AISYGDVKLACFYMNI 723
E P + + + D + ++ N+ + + R A G ++ +
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLER 277
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDE 782
+ S I D + + L H + + + V + D G T+ +AA G D+
Sbjct: 278 NKSGTIPSDSQGATPL-HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDD 336
Query: 783 FCNILIFNRA--NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
++ ++ ++N +K T LH AA++ ++LLL+N A ++A DV ++TPL
Sbjct: 337 VLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFR 396
Query: 841 ASETGNIGAAKILLSYNPDITLLN 864
A E G+ + L+ + L++
Sbjct: 397 ACEMGHKDVIQTLIKGGARVDLVD 420
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 467
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 468 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIK 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 144 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 203
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 204 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 258
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 309
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 310 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 364
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 365 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 422
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 423 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 482
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 483 NIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 110 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 169
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 170 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 229
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 230 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 280
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 281 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 340
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 341 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 399
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA 512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 480 ADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 535
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 536 RHEVIQFMLEHGA 548
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 392 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 451
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDKEGRTALHWSCNNGYLDAI 505
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 506 KLLLDFAAFPNQMENNEERYTPLDYA 531
Score = 58.8 bits (136), Expect = 8e-08
Identities = 90/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 179 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 238
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 239 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 293
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 352
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 353 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 408
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 466
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++K+ +T LH + N I+LLLD A N ++ R T
Sbjct: 467 GYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 526
Query: 837 PL 838
PL
Sbjct: 527 PL 528
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 132
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 133 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 248 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 308 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 363
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 364 AALSGHVSTVKLLLENNAQ 382
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 452 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDF 511
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 512 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 551
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 481 DPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 540
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 541 QFMLEHGALSIAAIQDIA 558
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/86 (26%), Positives = 43/86 (50%)
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+++ N A + ++ +TPL + ++ LL GA++N D ++ T LH A++ G
Sbjct: 33 LIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKG 92
Query: 846 NIGAAKILLSYNPDITLLNATEKTAL 871
N K+LL+ + + E T L
Sbjct: 93 NYRFMKLLLTRRANWMQKDLEEMTPL 118
Score = 33.5 bits (73), Expect = 3.4
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 805 LHLAAIN-NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
+H AA+N +K + RL++ N A + D TPL + A LL D+
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 864 NATEKTALAVAKDKVHLTIIDLI 886
+ +++TAL +A K + + L+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLL 100
>BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein.
Length = 367
Score = 92.3 bits (219), Expect = 7e-18
Identities = 88/351 (25%), Positives = 158/351 (45%), Gaps = 17/351 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A G + L+ ++N D + + LH A+ G ++ +L+ SGA +N K+
Sbjct: 15 AIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMW 74
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH AV + V+ +I +HS ++N +++ TPLH+A+ A ++I
Sbjct: 75 LTPLHRAVASRSEEAVQVLI---KHSA---DVNARDKNWQTPLHVAAANKAVKCAEVIIP 128
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLK 678
S ++ + +TA H+ + ++ L + +I + + K
Sbjct: 129 LLSSVNVSDRGGRTAL---HHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGH 185
Query: 679 LQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNS 738
L + L + + A T ++ K + A S G + + +N+ I N+
Sbjct: 186 LDVVALLIN--HGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVE--IDEINVYGNT 241
Query: 739 LCHPLCECQYCKRKTESCTDFDVNVC--DSNGFTALHYAARYGLDEFC-NILIFNRANVN 795
H C E D+ NV ++NGFT LH+AA C +L+ N A+VN
Sbjct: 242 ALHIACYNGQDAVVNE-LIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVN 300
Query: 796 CRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
++K ++PLH+ A++ + + L+ NG I+ +D NTPLH A+ G+
Sbjct: 301 IQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGH 351
Score = 90.6 bits (215), Expect = 2e-17
Identities = 51/149 (34%), Positives = 82/149 (55%), Gaps = 6/149 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G TALH A+++G +V LL G+ INA D + ALH+A+ GH +V+ +L++ G
Sbjct: 137 DRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHG 196
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A + K+ TPLH A +NG ++ VK ++ + I+ N GNT LH+A G
Sbjct: 197 AEVTCKDKKGYTPLHAAASNGQINVVKHLLNLG------VEIDEINVYGNTALHIACYNG 250
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ + LI++G+ + N+ T +A
Sbjct: 251 QDAVVNELIDYGANVNQPNNNGFTPLHFA 279
Score = 89.8 bits (213), Expect = 4e-17
Identities = 90/351 (25%), Positives = 160/351 (45%), Gaps = 37/351 (10%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYA-SSRGHQNVLLMLLHS 547
DS T LHVA+ G A I+E L+ G+ +NA D + LH A +SR + V +++ HS
Sbjct: 38 DSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHS 97
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A++N ++ + TPLH+A N + C + II ++N ++ G T LH A+
Sbjct: 98 -ADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLS------SVNVSDRGGRTALHHAALN 150
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKI 667
G+ + LL+ G+ + + + A +A + L V + + + ++
Sbjct: 151 GHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDV-----------VALLINHGAEV 199
Query: 668 SCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAIS-YGDVKL--ACF----- 719
+C+ +K + L + +N +++L + + I+ YG+ L AC+
Sbjct: 200 TCKDKKGYT------PLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDA 253
Query: 720 YMN--IDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTD--FDVNVCDSNGFTALHYA 775
+N IDY A + + H + E + DVN+ +G + LH
Sbjct: 254 VVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMT 313
Query: 776 ARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
A +G LI N ++C +K TPLH+AA ++I L+ +GA+
Sbjct: 314 AVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGAD 364
Score = 82.6 bits (195), Expect = 6e-15
Identities = 51/132 (38%), Positives = 70/132 (53%), Gaps = 1/132 (0%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VNV D G TALH+AA G E N+L+ AN+N +KK + LH AA V+ LL
Sbjct: 133 VNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALL 192
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA-KDKVH 879
+++GA + D TPLH A+ G I K LL+ +I +N TAL +A +
Sbjct: 193 INHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQD 252
Query: 880 LTIIDLIDNYAN 891
+ +LID AN
Sbjct: 253 AVVNELIDYGAN 264
Score = 79.4 bits (187), Expect = 5e-14
Identities = 53/169 (31%), Positives = 89/169 (52%), Gaps = 11/169 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T +D G T LH A+ +G+ +V+ LL +G EI+ ++ +ALH A G V+ L
Sbjct: 199 VTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNEL 258
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGH-LHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ GAN+NQ N + TPLH A + H C++ ++ ++G +NI ++ G +PLH+
Sbjct: 259 IDYGANVNQPNNNGFTPLHFAAASTHGALCLELLV----NNGADVNIQ--SKDGKSPLHM 312
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKT----AFDYAHNLRILQVLKS 648
+ G ++ LI++G E + T A Y H L I ++ S
Sbjct: 313 TAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITS 361
Score = 79.0 bits (186), Expect = 7e-14
Identities = 49/153 (32%), Positives = 74/153 (48%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +RD + T LHVA+ + E ++ + S +N +D +ALH+A+ GH ++ +L
Sbjct: 100 VNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLL 159
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GANIN + LH A GHL V +I H + C ++ G TPLH A
Sbjct: 160 LAKGANINAFDKKDRRALHWAAYMGHLDVVALLI---NHGA---EVTCKDKKGYTPLHAA 213
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G + + L+ G E N Y TA A
Sbjct: 214 ASNGQINVVKHLLNLGVEIDEINVYGNTALHIA 246
Score = 77.8 bits (183), Expect = 2e-13
Identities = 84/353 (23%), Positives = 148/353 (41%), Gaps = 15/353 (4%)
Query: 536 GHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANE 595
G + ML+H ++N + +K TPLH+A G ++ +I SG ++N +
Sbjct: 19 GDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLIL----SGARVNAK--DN 72
Query: 596 SGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFE 655
TPLH A E ++LI+H ++ + ++ +T A + ++ + P L
Sbjct: 73 MWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIP-LLS 131
Query: 656 YIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISY-GDV 714
++++ + + +++ NL L +A K R L +Y G +
Sbjct: 132 SVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFD-----KKDRRALHWAAYMGHL 186
Query: 715 KLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHY 774
+ +N + DK+ L Q K +++ + G TALH
Sbjct: 187 DVVALLINHG-AEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHI 245
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK-TVVIRLLLDNGANINAIDVA 833
A G D N LI ANVN N TPLH AA + + + LL++NGA++N
Sbjct: 246 ACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKD 305
Query: 834 RNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+PLH + G ++ L+ +I ++ T L VA H +I+ +
Sbjct: 306 GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTL 358
Score = 71.7 bits (168), Expect = 1e-11
Identities = 46/134 (34%), Positives = 67/134 (50%), Gaps = 2/134 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
++N D ALH+AA G + +LI + A V C++KK TPLH AA N + V++
Sbjct: 165 NINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKH 224
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+ G I+ I+V NT LH A G L+ Y ++ N T L A H
Sbjct: 225 LLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTH 284
Query: 880 --LTIIDLIDNYAN 891
L + L++N A+
Sbjct: 285 GALCLELLVNNGAD 298
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/129 (31%), Positives = 66/129 (51%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D+ T LH A +E +LI + A+VN R+K QTPLH+AA N ++
Sbjct: 67 VNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVI 126
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ +++N D T LH A+ G++ +LL+ +I + ++ AL A HL
Sbjct: 127 IPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHL 186
Query: 881 TIIDLIDNY 889
++ L+ N+
Sbjct: 187 DVVALLINH 195
Score = 66.9 bits (156), Expect = 3e-10
Identities = 70/314 (22%), Positives = 138/314 (43%), Gaps = 21/314 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D+ LT LH A V+ L++ +++NA D N + LH A++ ++
Sbjct: 67 VNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVI 126
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +++N + T LH A NGH+ V ++ + NIN ++ LH A
Sbjct: 127 IPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLL------AKGANINAFDKKDRRALHWA 180
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNL---FEYIHITS 661
+ G+ + LLI HG+E + ++ T A + + V+K NL + I++
Sbjct: 181 AYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLL-NLGVEIDEINVYG 239
Query: 662 SEVKKISCESEKPTSL-KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFY 720
+ I+C + + + +L + + N+ T + A ++G + C
Sbjct: 240 NTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLH------FAAASTHGAL---CLE 290
Query: 721 MNIDYSAFIAPDKEKSNSLCH-PLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYG 779
+ ++ A + + S H ++ + +T +++ D +G T LH AARYG
Sbjct: 291 LLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYG 350
Query: 780 LDEFCNILIFNRAN 793
+ N LI + A+
Sbjct: 351 HELLINTLITSGAD 364
Score = 32.7 bits (71), Expect = 5.9
Identities = 16/53 (30%), Positives = 28/53 (52%)
Query: 802 QTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
Q PL A + IR+L+ ++N +D + TPLH A+ G+ ++L+
Sbjct: 9 QPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLI 61
>AF039217-1|AAD02131.2| 1013|Homo sapiens inv candidate homolog
protein.
Length = 1013
Score = 91.5 bits (217), Expect = 1e-17
Identities = 81/364 (22%), Positives = 162/364 (44%), Gaps = 16/364 (4%)
Query: 509 ETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNN 568
+ LL+ G+++N TD ++ +ALH A+ +G+ + +LL AN QK++++ TPLHL +
Sbjct: 13 DALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRH 72
Query: 569 GHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNS 628
C+ ++ F ++ +++ T LH ++ + +LLI+H S + +
Sbjct: 73 RSPKCLALLLKFMAPG----EVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDV 128
Query: 629 YHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSD 688
K +A N + + T T S + E P + + + D
Sbjct: 129 EGKIPLHWAANHKDPSAVH--TVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 186
Query: 689 TNDASKTIENLKLIERILR-----AISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPL 743
+ ++ N+ + + R A G ++ + + S I D + + L H
Sbjct: 187 VLTSYESC-NITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPL-HYA 244
Query: 744 CECQYCKRKTESCTDFDV-NVCDSNGFTALHYAARYGLDEFCNILIFNRA--NVNCRNKK 800
+ + + V + D G T+ +AA G D+ ++ ++ ++N +K
Sbjct: 245 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 304
Query: 801 AQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
T LH AA++ ++LLL+N A ++A DV ++TPL A E G+ + L+ +
Sbjct: 305 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 364
Query: 861 TLLN 864
L++
Sbjct: 365 DLVD 368
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/159 (30%), Positives = 88/159 (55%), Gaps = 6/159 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G TALH A++ G + V+ LLE ++++ATD+ + + L A GH++V+ L+ G
Sbjct: 302 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 361
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + D ++ LH A G+ + +I KIN N + +G TPL A+ G
Sbjct: 362 ARVDLVDQDGHSLLHWAALGGNADVCQILI------ENKINPNVQDYAGRTPLQCAAYGG 415
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
Y +L+E+ ++P++Q+ +TA ++ N L +K
Sbjct: 416 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIK 454
Score = 79.8 bits (188), Expect = 4e-14
Identities = 97/389 (24%), Positives = 166/389 (42%), Gaps = 40/389 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV------ 540
++D + TALH ++ + V+ L++ S I D+ LH+A++ +
Sbjct: 92 TQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRC 151
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
+L + + +N ++ + TPLH AV +G++ V + S NI + TP
Sbjct: 152 ILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLT-----SYESCNITSYDNLFRTP 206
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL-QNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHI 659
LH A+ G+ I LL+E ++ +S T YA + +K + +
Sbjct: 207 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVK---------VFL 257
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
VK S + E TS + ++D +T+ +LK I A YG L
Sbjct: 258 KHPSVKDDS-DLEGRTSF----MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAA 312
Query: 720 YMN---------IDYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV--CDSN 767
++ ++ +A + A D K L CE + K ++ V D +
Sbjct: 313 ALSGHVSTVKLLLENNAQVDATDVMKHTPLFR-ACEMGH-KDVIQTLIKGGARVDLVDQD 370
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH+AA G + C ILI N+ N N ++ +TPL AA + +L++N A+
Sbjct: 371 GHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADP 430
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSY 856
N D T LH + G + A K+LL +
Sbjct: 431 NIQDKEGRTALHWSCNNGYLDAIKLLLDF 459
Score = 74.9 bits (176), Expect = 1e-12
Identities = 92/413 (22%), Positives = 171/413 (41%), Gaps = 20/413 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGS--EINATDLNECSALHYASSRGHQNVLLMLL 545
+D +T LH+ + H + LL+ + E++ D N+ +ALH+++ + + +L+
Sbjct: 58 KDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLI 117
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+NI +++ PLH A N+ V + + + + +N + G TPLH A
Sbjct: 118 KHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAV 177
Query: 606 KWGYEGIARLLIEHGS-EPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
G + +L + S + ++ +T +A L Q++ ++ + ++
Sbjct: 178 ADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIV---------HLLLERNKS 228
Query: 665 KKISCESEKPTSLKL---QNL--TLKCSDTNDASKTIENLKLIERILRAISYG--DVKLA 717
I +S+ T L N T+K + + K +L+ + A G DV
Sbjct: 229 GTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRT 288
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAAR 777
+ D +A DK +L K + V+ D T L A
Sbjct: 289 MLSLKSDIDINMA-DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACE 347
Query: 778 YGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTP 837
G + LI A V+ ++ + LH AA+ V ++L++N N N D A TP
Sbjct: 348 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 407
Query: 838 LHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
L A+ G I +L+ N D + + +TAL + + +L I L+ ++A
Sbjct: 408 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA 460
Score = 61.7 bits (143), Expect = 1e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH A++ G A + + L+E N D + L A+ G+ N + +L+ +
Sbjct: 368 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 427
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ + T LH + NNG+L +K ++ FA + N NE TPL A
Sbjct: 428 ADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMEN----NEERYTPLDYALLGE 483
Query: 609 YEGIARLLIEHGS 621
+ + ++EHG+
Sbjct: 484 RHEVIQFMLEHGA 496
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/146 (26%), Positives = 78/146 (53%), Gaps = 8/146 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A G +++TL++ G+ ++ D + S LH+A+ G+ +V +L+ + N N
Sbjct: 340 TPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNV 399
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A G+++C+ ++ E++ + N ++ G T LH + GY
Sbjct: 400 QDYAGRTPLQCAAYGGYINCMAVLM---ENNA---DPNIQDKEGRTALHWSCNNGYLDAI 453
Query: 614 RLLIEHGSEPS-LQNSYHK-TAFDYA 637
+LL++ + P+ ++N+ + T DYA
Sbjct: 454 KLLLDFAAFPNQMENNEERYTPLDYA 479
Score = 58.8 bits (136), Expect = 8e-08
Identities = 90/362 (24%), Positives = 148/362 (40%), Gaps = 24/362 (6%)
Query: 489 DSHGLTALHVASIHGKATIVET---LLEMG---SEINATDLNECSALHYASSRGHQNVLL 542
D G LH A+ H + V T +L+ S +N D + LH+A + G+ V+
Sbjct: 127 DVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVD 186
Query: 543 MLL-HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L + NI + TPLH A GH V ++ K ++ G TPL
Sbjct: 187 VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL-----ERNKSGTIPSDSQGATPL 241
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
H A++ + ++ ++H S + +T+F +A VL++ +L I I
Sbjct: 242 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTML-SLKSDIDINM 300
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYM 721
++ K + +L T+K N+A ++ + RA G +
Sbjct: 301 AD--KYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDV--IQT 356
Query: 722 NIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
I A + + +SL H C+ E+ + NV D G T L AA
Sbjct: 357 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN--KINPNVQDYAGRTPLQCAAYG 414
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID--VARNT 836
G +L+ N A+ N ++K+ +T LH + N I+LLLD A N ++ R T
Sbjct: 415 GYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYT 474
Query: 837 PL 838
PL
Sbjct: 475 PL 476
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D + TALH AA+ G F +L+ RAN ++ + TPLHL + + L
Sbjct: 21 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLAL 80
Query: 820 LLDNGA--NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL A ++ D + T LH ++ N K+L+ ++ +I + + K L
Sbjct: 81 LLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 134
Score = 49.6 bits (113), Expect = 5e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMG-SEINATDLNECSALHYASSRGHQNVLLM 543
+TS D+ T LH A++ G A IV LLE S +D + LHYA+ + +
Sbjct: 196 ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 255
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L + + +++ T A G ++ ++ I+IN A++ G T LH
Sbjct: 256 FLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKS----DIDINMADKYGGTALHA 311
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ +LL+E+ ++
Sbjct: 312 AALSGHVSTVKLLLENNAQ 330
Score = 39.5 bits (88), Expect = 0.052
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G T L A+ G + L+E ++ N D +ALH++ + G+ + + +LL
Sbjct: 400 QDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDF 459
Query: 548 GANINQ--KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
A NQ N ++ TPL A+ G H + I + EH I
Sbjct: 460 AAFPNQMENNEERYTPLDYAL-LGERH--EVIQFMLEHGALSI 499
Score = 37.9 bits (84), Expect = 0.16
Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 8/114 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH--SGANI 551
TALH+A+ G ++ LL + DL E + LH + L +LL + +
Sbjct: 31 TALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEV 90
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+ ++ +K T LH + + VK +I +H NI + G PLH A+
Sbjct: 91 DTQDKNKQTALHWSAYYNNPEHVKLLI---KHDS---NIGIPDVEGKIPLHWAA 138
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC--RNKKAQTPLHLAAINNKTVVI 817
D N+ D G TALH++ G + +L+ A N N++ TPL A + + VI
Sbjct: 429 DPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVI 488
Query: 818 RLLLDNGA-NINAI-DVA 833
+ +L++GA +I AI D+A
Sbjct: 489 QFMLEHGALSIAAIQDIA 506
>BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein.
Length = 306
Score = 90.6 bits (215), Expect = 2e-17
Identities = 51/149 (34%), Positives = 82/149 (55%), Gaps = 6/149 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G TALH A+++G +V LL G+ INA D + ALH+A+ GH +V+ +L++ G
Sbjct: 76 DRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHG 135
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A + K+ TPLH A +NG ++ VK ++ + I+ N GNT LH+A G
Sbjct: 136 AEVTCKDKKGYTPLHAAASNGQINVVKHLLNLG------VEIDEINVYGNTALHIACYNG 189
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ + LI++G+ + N+ T +A
Sbjct: 190 QDAVVNELIDYGANVNQPNNNGFTPLHFA 218
Score = 84.2 bits (199), Expect = 2e-15
Identities = 42/133 (31%), Positives = 83/133 (62%), Gaps = 7/133 (5%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL-MLLHSGA 549
+G TALH+A +G+ +V L++ G+ +N + N + LH+A++ H + L +L+++GA
Sbjct: 177 YGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGA 236
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
++N ++ D +PLH+ +G + +I ++ G I+C ++ GNTPLH+A+++G+
Sbjct: 237 DVNIQSKDGKSPLHMTAVHGRFTRSQTLI---QNGGE---IDCVDKDGNTPLHVAARYGH 290
Query: 610 EGIARLLIEHGSE 622
E + LI G++
Sbjct: 291 ELLINTLITSGAD 303
Score = 82.6 bits (195), Expect = 6e-15
Identities = 51/132 (38%), Positives = 70/132 (53%), Gaps = 1/132 (0%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VNV D G TALH+AA G E N+L+ AN+N +KK + LH AA V+ LL
Sbjct: 72 VNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALL 131
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA-KDKVH 879
+++GA + D TPLH A+ G I K LL+ +I +N TAL +A +
Sbjct: 132 INHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQD 191
Query: 880 LTIIDLIDNYAN 891
+ +LID AN
Sbjct: 192 AVVNELIDYGAN 203
Score = 79.4 bits (187), Expect = 5e-14
Identities = 53/169 (31%), Positives = 89/169 (52%), Gaps = 11/169 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T +D G T LH A+ +G+ +V+ LL +G EI+ ++ +ALH A G V+ L
Sbjct: 138 VTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNEL 197
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGH-LHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ GAN+NQ N + TPLH A + H C++ ++ ++G +NI ++ G +PLH+
Sbjct: 198 IDYGANVNQPNNNGFTPLHFAAASTHGALCLELLV----NNGADVNIQ--SKDGKSPLHM 251
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKT----AFDYAHNLRILQVLKS 648
+ G ++ LI++G E + T A Y H L I ++ S
Sbjct: 252 TAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITS 300
Score = 79.0 bits (186), Expect = 7e-14
Identities = 49/153 (32%), Positives = 74/153 (48%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +RD + T LHVA+ + E ++ + S +N +D +ALH+A+ GH ++ +L
Sbjct: 39 VNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLL 98
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L GANIN + LH A GHL V +I H + C ++ G TPLH A
Sbjct: 99 LAKGANINAFDKKDRRALHWAAYMGHLDVVALLI---NHGA---EVTCKDKKGYTPLHAA 152
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G + + L+ G E N Y TA A
Sbjct: 153 ASNGQINVVKHLLNLGVEIDEINVYGNTALHIA 185
Score = 75.8 bits (178), Expect = 6e-13
Identities = 78/303 (25%), Positives = 137/303 (45%), Gaps = 17/303 (5%)
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
SGA +N K+ TPLH AV + V+ +I +HS ++N +++ TPLH+A+
Sbjct: 2 SGARVNAKDNMWLTPLHRAVASRSEEAVQVLI---KHSA---DVNARDKNWQTPLHVAAA 55
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKK 666
A ++I S ++ + +TA H+ + ++ L + +I + + K
Sbjct: 56 NKAVKCAEVIIPLLSSVNVSDRGGRTAL---HHAALNGHVEMVNLLLAKGANINAFDKKD 112
Query: 667 ISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYS 726
L + L + + A T ++ K + A S G + + +N+
Sbjct: 113 RRALHWAAYMGHLDVVALLIN--HGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVE 170
Query: 727 AFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVC--DSNGFTALHYAARYGLDEFC 784
I N+ H C E D+ NV ++NGFT LH+AA C
Sbjct: 171 --IDEINVYGNTALHIACYNGQDAVVNE-LIDYGANVNQPNNNGFTPLHFAAASTHGALC 227
Query: 785 -NILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASE 843
+L+ N A+VN ++K ++PLH+ A++ + + L+ NG I+ +D NTPLH A+
Sbjct: 228 LELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAAR 287
Query: 844 TGN 846
G+
Sbjct: 288 YGH 290
Score = 71.7 bits (168), Expect = 1e-11
Identities = 46/134 (34%), Positives = 67/134 (50%), Gaps = 2/134 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
++N D ALH+AA G + +LI + A V C++KK TPLH AA N + V++
Sbjct: 104 NINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKH 163
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+ G I+ I+V NT LH A G L+ Y ++ N T L A H
Sbjct: 164 LLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTH 223
Query: 880 --LTIIDLIDNYAN 891
L + L++N A+
Sbjct: 224 GALCLELLVNNGAD 237
Score = 70.1 bits (164), Expect = 3e-11
Identities = 78/325 (24%), Positives = 145/325 (44%), Gaps = 37/325 (11%)
Query: 515 GSEINATDLNECSALHYA-SSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHC 573
G+ +NA D + LH A +SR + V +++ HS A++N ++ + TPLH+A N + C
Sbjct: 3 GARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHS-ADVNARDKNWQTPLHVAAANKAVKC 61
Query: 574 VKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTA 633
+ II ++N ++ G T LH A+ G+ + LL+ G+ + + + A
Sbjct: 62 AEVIIPLLS------SVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRA 115
Query: 634 FDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDAS 693
+A + L V + + + +++C+ +K + L + +N
Sbjct: 116 LHWAAYMGHLDV-----------VALLINHGAEVTCKDKKGYT------PLHAAASNGQI 158
Query: 694 KTIENLKLIERILRAIS-YGDVKL--ACF-----YMN--IDYSAFIAPDKEKSNSLCHPL 743
+++L + + I+ YG+ L AC+ +N IDY A + + H
Sbjct: 159 NVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFA 218
Query: 744 CECQYCKRKTESCTD--FDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKA 801
+ E + DVN+ +G + LH A +G LI N ++C +K
Sbjct: 219 AASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDG 278
Query: 802 QTPLHLAAINNKTVVIRLLLDNGAN 826
TPLH+AA ++I L+ +GA+
Sbjct: 279 NTPLHVAARYGHELLINTLITSGAD 303
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/129 (31%), Positives = 66/129 (51%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D+ T LH A +E +LI + A+VN R+K QTPLH+AA N ++
Sbjct: 6 VNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVI 65
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ +++N D T LH A+ G++ +LL+ +I + ++ AL A HL
Sbjct: 66 IPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHL 125
Query: 881 TIIDLIDNY 889
++ L+ N+
Sbjct: 126 DVVALLINH 134
Score = 67.3 bits (157), Expect = 2e-10
Identities = 38/124 (30%), Positives = 62/124 (50%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D N T LH AA + ++I ++VN ++ +T LH AA+N ++ L
Sbjct: 38 DVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNL 97
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL GANINA D LH A+ G++ +L+++ ++T + T L A
Sbjct: 98 LLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQ 157
Query: 880 LTII 883
+ ++
Sbjct: 158 INVV 161
Score = 66.9 bits (156), Expect = 3e-10
Identities = 70/314 (22%), Positives = 138/314 (43%), Gaps = 21/314 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D+ LT LH A V+ L++ +++NA D N + LH A++ ++
Sbjct: 6 VNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVI 65
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +++N + T LH A NGH+ V ++ + NIN ++ LH A
Sbjct: 66 IPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLL------AKGANINAFDKKDRRALHWA 119
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNL---FEYIHITS 661
+ G+ + LLI HG+E + ++ T A + + V+K NL + I++
Sbjct: 120 AYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLL-NLGVEIDEINVYG 178
Query: 662 SEVKKISCESEKPTSL-KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFY 720
+ I+C + + + +L + + N+ T + A ++G + C
Sbjct: 179 NTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLH------FAAASTHGAL---CLE 229
Query: 721 MNIDYSAFIAPDKEKSNSLCH-PLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYG 779
+ ++ A + + S H ++ + +T +++ D +G T LH AARYG
Sbjct: 230 LLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYG 289
Query: 780 LDEFCNILIFNRAN 793
+ N LI + A+
Sbjct: 290 HELLINTLITSGAD 303
Score = 60.5 bits (140), Expect = 3e-08
Identities = 40/120 (33%), Positives = 58/120 (48%), Gaps = 1/120 (0%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK-TVVIRLLLDNGAN 826
G TALH A G D N LI ANVN N TPLH AA + + + LL++NGA+
Sbjct: 178 GNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGAD 237
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+N +PLH + G ++ L+ +I ++ T L VA H +I+ +
Sbjct: 238 VNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTL 297
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/95 (26%), Positives = 50/95 (52%)
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A VN ++ TPLH A + +++L+ + A++NA D TPLH A+ + A+
Sbjct: 4 ARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAE 63
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+++ + + + +TAL A H+ +++L+
Sbjct: 64 VIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLL 98
>BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein
protein.
Length = 1280
Score = 90.2 bits (214), Expect = 3e-17
Identities = 93/406 (22%), Positives = 181/406 (44%), Gaps = 23/406 (5%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYAS-----SRGHQNVLLM 543
D+ G TAL A+ G IVE LL+ G+E+N D++ +AL A+ S+GH +V+ +
Sbjct: 525 DNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSL 584
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L+ GA ++ + D TPL +A GH+ V ++ G +++ + +G TPL
Sbjct: 585 LIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLL----EGGA--DVDHTDNNGRTPLLA 638
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
A+ G+ + L+ G+ +S +T A ++V+++ + H +
Sbjct: 639 AASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAG 698
Query: 664 VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAIS--YGDVKLACFYM 721
+ + + L + L + + TN+ I+N I IL + Y V++
Sbjct: 699 WTPLHMAAFEGHRLICEALIEQGARTNE----IDNDGRIPFILASQEGHYDCVQILLENK 754
Query: 722 -NIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGL 780
NID + + N+L E + DVN D++G L+ A
Sbjct: 755 SNIDQRGY-----DGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQ 809
Query: 781 DEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
+ N ANV + + +T LH++ ++++L+ A++NA D + + L
Sbjct: 810 LTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQS 869
Query: 841 ASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
A+ G++ ++L+ + + TAL +A + H+ ++ ++
Sbjct: 870 AAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 915
Score = 87.4 bits (207), Expect = 2e-16
Identities = 91/374 (24%), Positives = 169/374 (45%), Gaps = 24/374 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G+T L VA+ G +V+ LLE G++++ TD N + L A+S GH +V+ LL G
Sbjct: 596 DKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWG 655
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + + T L +A G++ V+ ++ R ++ N +++G TPLH+A+ G
Sbjct: 656 AAVDSIDSEGRTVLSIASAQGNVEVVRTLL------DRGLDENHRDDAGWTPLHMAAFEG 709
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAH---NLRILQVLKSCTPNLFEYIHITSSEVK 665
+ I LIE G+ + ++ + F A + +Q+L N+ + + + ++
Sbjct: 710 HRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALR 769
Query: 666 KISCESEKP--TSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNI 723
+ E + L + C D D T+ L L ++ A + +
Sbjct: 770 VAALEGHRDIVELLFSHGADVNCKDA-DGRPTLYILALENQLTMAEYF-----------L 817
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKR-KTESCTDFDVNVCDSNGFTALHYAARYGLDE 782
+ A + + + H C + + + DVN D+ +AL AA G +
Sbjct: 818 ENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVK 877
Query: 783 FCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDAS 842
+LI + A V+ + T L +AA V+++LL++GA+ N D T + A+
Sbjct: 878 VVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAA 937
Query: 843 ETGNIGAAKILLSY 856
+ G+ K+L Y
Sbjct: 938 KNGHSQIIKLLEKY 951
Score = 80.2 bits (189), Expect = 3e-14
Identities = 52/203 (25%), Positives = 107/203 (52%), Gaps = 7/203 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ G L++ ++ + T+ E LE G+ + A+D +ALH + +GH ++ +L+
Sbjct: 793 KDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAY 852
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A++N + +K + L A GH+ V+ +I EH G ++ C G T L +A++
Sbjct: 853 HADVNAADNEKRSALQSAAWQGHVKVVQLLI---EH-GAVVDHTC--NQGATALCIAAQE 906
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH-ITSSEVKK 666
G+ + ++L+EHG++P+ + + +TA A Q++K ++ + S V
Sbjct: 907 GHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLNGCSPSPVHT 966
Query: 667 ISCESEKPTSLKLQNLTLKCSDT 689
+ + + S K+Q+LT+K + +
Sbjct: 967 MEQKPLQSLSSKVQSLTIKSNSS 989
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/142 (31%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
S DS G T L +AS G +V TLL+ G + N D + LH A+ GH+ + L+
Sbjct: 660 SIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIE 719
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA N+ + D P LA GH CV+ ++ K NI+ G L +A+
Sbjct: 720 QGARTNEIDNDGRIPFILASQEGHYDCVQILL------ENKSNIDQRGYDGRNALRVAAL 773
Query: 607 WGYEGIARLLIEHGSEPSLQNS 628
G+ I LL HG++ + +++
Sbjct: 774 EGHRDIVELLFSHGADVNCKDA 795
Score = 74.9 bits (176), Expect = 1e-12
Identities = 45/145 (31%), Positives = 74/145 (51%), Gaps = 6/145 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
DS+G T L A+ G +V L+ G+++ D + + L A+ +GH V+ L+ G
Sbjct: 393 DSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCG 452
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
ANIN + D T L A GH V A++Y + ++CA+ T L A+ G
Sbjct: 453 ANINHTDQDGWTALRSAAWGGHTEVVSALLYAG------VKVDCADADSRTALRAAAWGG 506
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTA 633
+E I L++HG+E + ++ +TA
Sbjct: 507 HEDIVLNLLQHGAEVNKADNEGRTA 531
Score = 72.5 bits (170), Expect = 6e-12
Identities = 46/149 (30%), Positives = 75/149 (50%), Gaps = 6/149 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D+HG T L +A+ G +V L+ G+ IN TD + +AL A+ GH V+ LL++G
Sbjct: 426 DAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAG 485
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ + D T L A GH V ++ +H +N A+ G T L A+ G
Sbjct: 486 VKVDCADADSRTALRAAAWGGHEDIVLNLL---QHGAE---VNKADNEGRTALIAAAYMG 539
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ I L++HG+E + ++ +TA A
Sbjct: 540 HREIVEHLLDHGAEVNHEDVDGRTALSVA 568
Score = 65.7 bits (153), Expect = 7e-10
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 6/134 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
R G AL VA++ G IVE L G+++N D + L+ + + L +
Sbjct: 760 RGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLEN 819
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GAN+ + + T LH++ GH+ V+ +I A H+ ++N A+ + L A+
Sbjct: 820 GANVEASDAEGRTALHVSCWQGHMEMVQVLI--AYHA----DVNAADNEKRSALQSAAWQ 873
Query: 608 GYEGIARLLIEHGS 621
G+ + +LLIEHG+
Sbjct: 874 GHVKVVQLLIEHGA 887
Score = 64.1 bits (149), Expect = 2e-09
Identities = 40/136 (29%), Positives = 67/136 (49%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V D+ G TALH + G E +LI A+VN + + ++ L AA V++L
Sbjct: 822 NVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQL 881
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+++GA ++ T L A++ G+I ++LL + D + +TA+ VA H
Sbjct: 882 LIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGH 941
Query: 880 LTIIDLIDNYANKYAN 895
II L++ Y N
Sbjct: 942 SQIIKLLEKYGASSLN 957
Score = 63.7 bits (148), Expect = 3e-09
Identities = 43/139 (30%), Positives = 71/139 (51%), Gaps = 11/139 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D+ TAL A+ G IV LL+ G+E+N D +AL A+ GH+ ++ LL G
Sbjct: 492 DADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHG 551
Query: 549 ANINQKNIDKNTPLHLAV-----NNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
A +N +++D T L +A + GH V +I R ++ ++ G TPL +
Sbjct: 552 AEVNHEDVDGRTALSVAALCVPASKGHASVVSLLI------DRGAEVDHCDKDGMTPLLV 605
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ + LL+E G++
Sbjct: 606 AAYEGHVDVVDLLLEGGAD 624
Score = 62.9 bits (146), Expect = 5e-09
Identities = 43/123 (34%), Positives = 57/123 (46%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN CDSNG T L AA G + N+L+ A++ + TPL LAA T V+ L
Sbjct: 389 VNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCL 448
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ GANIN D T L A+ G+ LL + +A +TAL A H
Sbjct: 449 IGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHE 508
Query: 881 TII 883
I+
Sbjct: 509 DIV 511
Score = 60.5 bits (140), Expect = 3e-08
Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 11/139 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G TAL A+ G +V LL G +++ D + +AL A+ GH++++L LL G
Sbjct: 459 DQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHG 518
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA---- 604
A +N+ + + T L A GH V+ ++ +H +N + G T L +A
Sbjct: 519 AEVNKADNEGRTALIAAAYMGHREIVEHLL---DHGA---EVNHEDVDGRTALSVAALCV 572
Query: 605 -SKWGYEGIARLLIEHGSE 622
+ G+ + LLI+ G+E
Sbjct: 573 PASKGHASVVSLLIDRGAE 591
Score = 55.2 bits (127), Expect = 1e-06
Identities = 37/132 (28%), Positives = 65/132 (49%), Gaps = 5/132 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
++N D +G+TAL AA G E + L++ V+C + ++T L AA ++
Sbjct: 454 NINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLN 513
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA----- 874
LL +GA +N D T L A+ G+ + LL + ++ + +TAL+VA
Sbjct: 514 LLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVP 573
Query: 875 KDKVHLTIIDLI 886
K H +++ L+
Sbjct: 574 ASKGHASVVSLL 585
Score = 54.8 bits (126), Expect = 1e-06
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ + D++G T L AAR G + N LI AN+N ++ T L AA T V+
Sbjct: 421 DLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSA 480
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL G ++ D T L A+ G+ LL + ++ + +TAL A H
Sbjct: 481 LLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGH 540
Query: 880 LTIID-LIDNYA 890
I++ L+D+ A
Sbjct: 541 REIVEHLLDHGA 552
Score = 54.4 bits (125), Expect = 2e-06
Identities = 38/132 (28%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAI-----NNKT 814
+VN D+ G TAL AA G E L+ + A VN + +T L +AA+
Sbjct: 520 EVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHA 579
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V+ LL+D GA ++ D TPL A+ G++ +LL D+ + +T L A
Sbjct: 580 SVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAA 639
Query: 875 KDKVHLTIIDLI 886
H ++++ +
Sbjct: 640 ASMGHASVVNTL 651
Score = 53.6 bits (123), Expect = 3e-06
Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DV+ D+NG T L AA G N L+F A V+ + + +T L +A+ V+R
Sbjct: 624 DVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRT 683
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LLD G + N D A TPLH A+ G+ + L+ ++ + +A + H
Sbjct: 684 LLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGH 743
Query: 880 LTIID-LIDNYAN 891
+ L++N +N
Sbjct: 744 YDCVQILLENKSN 756
Score = 52.8 bits (121), Expect = 5e-06
Identities = 36/126 (28%), Positives = 62/126 (49%), Gaps = 6/126 (4%)
Query: 508 VETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVN 567
+ TLL+ G+ +N D N + L A+ G +V+ +L+ GA++ ++ +TPL LA
Sbjct: 379 IRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAAR 438
Query: 568 NGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQN 627
GH V +I G NIN ++ G T L A+ G+ + L+ G + +
Sbjct: 439 QGHTKVVNCLI------GCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCAD 492
Query: 628 SYHKTA 633
+ +TA
Sbjct: 493 ADSRTA 498
Score = 50.0 bits (114), Expect = 4e-05
Identities = 27/93 (29%), Positives = 49/93 (52%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D+ +AL A+ G +V+ L+E G+ ++ T +AL A+ GH +V+ +L
Sbjct: 856 VNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 915
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAI 577
L GA+ N + T + +A NGH +K +
Sbjct: 916 LEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 948
Score = 48.0 bits (109), Expect = 1e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 1/137 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N D G+T LH AA G C LI A N + + P LA+ +++
Sbjct: 690 DENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQI 749
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+N +NI+ L A+ G+ ++L S+ D+ +A + L + +
Sbjct: 750 LLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQ 809
Query: 880 LTIID-LIDNYANKYAN 895
LT+ + ++N AN A+
Sbjct: 810 LTMAEYFLENGANVEAS 826
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/105 (26%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Query: 782 EFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDA 841
E +L+ A+VN + + + A + IR LLDNGA++N D T L +A
Sbjct: 346 EVLQLLVKAGAHVNSEDDRTSCIVRQALEREDS--IRTLLDNGASVNQCDSNGRTLLANA 403
Query: 842 SETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+ +G++ +L+S D+ + +A T L +A + H +++ +
Sbjct: 404 AYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCL 448
Score = 37.5 bits (83), Expect = 0.21
Identities = 27/100 (27%), Positives = 45/100 (45%)
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
L+ N A+VN + +T L AA + V+ LL+ GA++ D +TPL A+ G+
Sbjct: 382 LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGH 441
Query: 847 IGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
L+ +I + TAL A H ++ +
Sbjct: 442 TKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSAL 481
>AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens cDNA
FLJ45589 fis, clone BRTHA3014547, weakly similar to
Ankyrin 1. ).
Length = 1375
Score = 90.2 bits (214), Expect = 3e-17
Identities = 93/406 (22%), Positives = 181/406 (44%), Gaps = 23/406 (5%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYAS-----SRGHQNVLLM 543
D+ G TAL A+ G IVE LL+ G+E+N D++ +AL A+ S+GH +V+ +
Sbjct: 620 DNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSL 679
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L+ GA ++ + D TPL +A GH+ V ++ G +++ + +G TPL
Sbjct: 680 LIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLL----EGGA--DVDHTDNNGRTPLLA 733
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
A+ G+ + L+ G+ +S +T A ++V+++ + H +
Sbjct: 734 AASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAG 793
Query: 664 VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAIS--YGDVKLACFYM 721
+ + + L + L + + TN+ I+N I IL + Y V++
Sbjct: 794 WTPLHMAAFEGHRLICEALIEQGARTNE----IDNDGRIPFILASQEGHYDCVQILLENK 849
Query: 722 -NIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGL 780
NID + + N+L E + DVN D++G L+ A
Sbjct: 850 SNIDQRGY-----DGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQ 904
Query: 781 DEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
+ N ANV + + +T LH++ ++++L+ A++NA D + + L
Sbjct: 905 LTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQS 964
Query: 841 ASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
A+ G++ ++L+ + + TAL +A + H+ ++ ++
Sbjct: 965 AAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 1010
Score = 87.4 bits (207), Expect = 2e-16
Identities = 91/374 (24%), Positives = 169/374 (45%), Gaps = 24/374 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G+T L VA+ G +V+ LLE G++++ TD N + L A+S GH +V+ LL G
Sbjct: 691 DKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWG 750
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + + T L +A G++ V+ ++ R ++ N +++G TPLH+A+ G
Sbjct: 751 AAVDSIDSEGRTVLSIASAQGNVEVVRTLL------DRGLDENHRDDAGWTPLHMAAFEG 804
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAH---NLRILQVLKSCTPNLFEYIHITSSEVK 665
+ I LIE G+ + ++ + F A + +Q+L N+ + + + ++
Sbjct: 805 HRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALR 864
Query: 666 KISCESEKP--TSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNI 723
+ E + L + C D D T+ L L ++ A + +
Sbjct: 865 VAALEGHRDIVELLFSHGADVNCKDA-DGRPTLYILALENQLTMAEYF-----------L 912
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKR-KTESCTDFDVNVCDSNGFTALHYAARYGLDE 782
+ A + + + H C + + + DVN D+ +AL AA G +
Sbjct: 913 ENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVK 972
Query: 783 FCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDAS 842
+LI + A V+ + T L +AA V+++LL++GA+ N D T + A+
Sbjct: 973 VVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAA 1032
Query: 843 ETGNIGAAKILLSY 856
+ G+ K+L Y
Sbjct: 1033 KNGHSQIIKLLEKY 1046
Score = 80.2 bits (189), Expect = 3e-14
Identities = 52/203 (25%), Positives = 107/203 (52%), Gaps = 7/203 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ G L++ ++ + T+ E LE G+ + A+D +ALH + +GH ++ +L+
Sbjct: 888 KDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAY 947
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A++N + +K + L A GH+ V+ +I EH G ++ C G T L +A++
Sbjct: 948 HADVNAADNEKRSALQSAAWQGHVKVVQLLI---EH-GAVVDHTC--NQGATALCIAAQE 1001
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH-ITSSEVKK 666
G+ + ++L+EHG++P+ + + +TA A Q++K ++ + S V
Sbjct: 1002 GHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLNGCSPSPVHT 1061
Query: 667 ISCESEKPTSLKLQNLTLKCSDT 689
+ + + S K+Q+LT+K + +
Sbjct: 1062 MEQKPLQSLSSKVQSLTIKSNSS 1084
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/142 (31%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
S DS G T L +AS G +V TLL+ G + N D + LH A+ GH+ + L+
Sbjct: 755 SIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIE 814
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA N+ + D P LA GH CV+ ++ K NI+ G L +A+
Sbjct: 815 QGARTNEIDNDGRIPFILASQEGHYDCVQILL------ENKSNIDQRGYDGRNALRVAAL 868
Query: 607 WGYEGIARLLIEHGSEPSLQNS 628
G+ I LL HG++ + +++
Sbjct: 869 EGHRDIVELLFSHGADVNCKDA 890
Score = 73.3 bits (172), Expect = 3e-12
Identities = 45/145 (31%), Positives = 73/145 (50%), Gaps = 6/145 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
DS+G T L A+ G +V L+ G+++ D + + L A+ +GH V+ L+ G
Sbjct: 488 DSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCG 547
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
ANIN + D T L A GH V A++Y + ++CA+ T L A+ G
Sbjct: 548 ANINHTDQDGWTALRSAAWGGHTEVVSALLYAG------VKVDCADADSRTALRAAAWGG 601
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTA 633
E I L++HG+E + ++ +TA
Sbjct: 602 REDIVLNLLQHGAEVNKADNEGRTA 626
Score = 69.3 bits (162), Expect = 6e-11
Identities = 45/149 (30%), Positives = 74/149 (49%), Gaps = 6/149 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D+HG T L +A+ G +V L+ G+ IN TD + +AL A+ GH V+ LL++G
Sbjct: 521 DAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAG 580
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ + D T L A G V ++ +H +N A+ G T L A+ G
Sbjct: 581 VKVDCADADSRTALRAAAWGGREDIVLNLL---QHGAE---VNKADNEGRTALIAAAYMG 634
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ I L++HG+E + ++ +TA A
Sbjct: 635 HREIVEHLLDHGAEVNHEDVDGRTALSVA 663
Score = 65.7 bits (153), Expect = 7e-10
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 6/134 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
R G AL VA++ G IVE L G+++N D + L+ + + L +
Sbjct: 855 RGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLEN 914
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GAN+ + + T LH++ GH+ V+ +I A H+ ++N A+ + L A+
Sbjct: 915 GANVEASDAEGRTALHVSCWQGHMEMVQVLI--AYHA----DVNAADNEKRSALQSAAWQ 968
Query: 608 GYEGIARLLIEHGS 621
G+ + +LLIEHG+
Sbjct: 969 GHVKVVQLLIEHGA 982
Score = 64.9 bits (151), Expect = 1e-09
Identities = 43/139 (30%), Positives = 72/139 (51%), Gaps = 11/139 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D+ TAL A+ G+ IV LL+ G+E+N D +AL A+ GH+ ++ LL G
Sbjct: 587 DADSRTALRAAAWGGREDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHG 646
Query: 549 ANINQKNIDKNTPLHLA-----VNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
A +N +++D T L +A + GH V +I R ++ ++ G TPL +
Sbjct: 647 AEVNHEDVDGRTALSVAALCVPASKGHASVVSLLI------DRGAEVDHCDKDGMTPLLV 700
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ + LL+E G++
Sbjct: 701 AAYEGHVDVVDLLLEGGAD 719
Score = 64.1 bits (149), Expect = 2e-09
Identities = 40/136 (29%), Positives = 67/136 (49%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V D+ G TALH + G E +LI A+VN + + ++ L AA V++L
Sbjct: 917 NVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQL 976
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+++GA ++ T L A++ G+I ++LL + D + +TA+ VA H
Sbjct: 977 LIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGH 1036
Query: 880 LTIIDLIDNYANKYAN 895
II L++ Y N
Sbjct: 1037 SQIIKLLEKYGASSLN 1052
Score = 62.5 bits (145), Expect = 6e-09
Identities = 41/114 (35%), Positives = 54/114 (47%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN CDSNG T L AA G + N+L+ A++ + TPL LAA T V+ L
Sbjct: 484 VNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCL 543
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
+ GANIN D T L A+ G+ LL + +A +TAL A
Sbjct: 544 IGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAA 597
Score = 56.4 bits (130), Expect = 4e-07
Identities = 37/132 (28%), Positives = 66/132 (50%), Gaps = 5/132 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
++N D +G+TAL AA G E + L++ V+C + ++T L AA + ++
Sbjct: 549 NINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGREDIVLN 608
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA----- 874
LL +GA +N D T L A+ G+ + LL + ++ + +TAL+VA
Sbjct: 609 LLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVP 668
Query: 875 KDKVHLTIIDLI 886
K H +++ L+
Sbjct: 669 ASKGHASVVSLL 680
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/132 (30%), Positives = 61/132 (46%), Gaps = 1/132 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ + D++G T L AAR G + N LI AN+N ++ T L AA T V+
Sbjct: 516 DLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSA 575
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL G ++ D T L A+ G LL + ++ + +TAL A H
Sbjct: 576 LLYAGVKVDCADADSRTALRAAAWGGREDIVLNLLQHGAEVNKADNEGRTALIAAAYMGH 635
Query: 880 LTIID-LIDNYA 890
I++ L+D+ A
Sbjct: 636 REIVEHLLDHGA 647
Score = 54.4 bits (125), Expect = 2e-06
Identities = 38/132 (28%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAI-----NNKT 814
+VN D+ G TAL AA G E L+ + A VN + +T L +AA+
Sbjct: 615 EVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHA 674
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V+ LL+D GA ++ D TPL A+ G++ +LL D+ + +T L A
Sbjct: 675 SVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAA 734
Query: 875 KDKVHLTIIDLI 886
H ++++ +
Sbjct: 735 ASMGHASVVNTL 746
Score = 53.6 bits (123), Expect = 3e-06
Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DV+ D+NG T L AA G N L+F A V+ + + +T L +A+ V+R
Sbjct: 719 DVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRT 778
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LLD G + N D A TPLH A+ G+ + L+ ++ + +A + H
Sbjct: 779 LLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGH 838
Query: 880 LTIID-LIDNYAN 891
+ L++N +N
Sbjct: 839 YDCVQILLENKSN 851
Score = 52.8 bits (121), Expect = 5e-06
Identities = 36/126 (28%), Positives = 62/126 (49%), Gaps = 6/126 (4%)
Query: 508 VETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVN 567
+ TLL+ G+ +N D N + L A+ G +V+ +L+ GA++ ++ +TPL LA
Sbjct: 474 IRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAAR 533
Query: 568 NGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQN 627
GH V +I G NIN ++ G T L A+ G+ + L+ G + +
Sbjct: 534 QGHTKVVNCLI------GCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCAD 587
Query: 628 SYHKTA 633
+ +TA
Sbjct: 588 ADSRTA 593
Score = 50.0 bits (114), Expect = 4e-05
Identities = 27/93 (29%), Positives = 49/93 (52%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D+ +AL A+ G +V+ L+E G+ ++ T +AL A+ GH +V+ +L
Sbjct: 951 VNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 1010
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAI 577
L GA+ N + T + +A NGH +K +
Sbjct: 1011 LEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 1043
Score = 48.0 bits (109), Expect = 1e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 1/137 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N D G+T LH AA G C LI A N + + P LA+ +++
Sbjct: 785 DENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQI 844
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+N +NI+ L A+ G+ ++L S+ D+ +A + L + +
Sbjct: 845 LLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQ 904
Query: 880 LTIID-LIDNYANKYAN 895
LT+ + ++N AN A+
Sbjct: 905 LTMAEYFLENGANVEAS 921
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/105 (26%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Query: 782 EFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDA 841
E +L+ A+VN + + + A + IR LLDNGA++N D T L +A
Sbjct: 441 EVLQLLVKAGAHVNSEDDRTSCIVRQALEREDS--IRTLLDNGASVNQCDSNGRTLLANA 498
Query: 842 SETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+ +G++ +L+S D+ + +A T L +A + H +++ +
Sbjct: 499 AYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCL 543
Score = 37.5 bits (83), Expect = 0.21
Identities = 27/100 (27%), Positives = 45/100 (45%)
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
L+ N A+VN + +T L AA + V+ LL+ GA++ D +TPL A+ G+
Sbjct: 477 LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGH 536
Query: 847 IGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
L+ +I + TAL A H ++ +
Sbjct: 537 TKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSAL 576
>AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein.
Length = 1089
Score = 90.2 bits (214), Expect = 3e-17
Identities = 93/406 (22%), Positives = 181/406 (44%), Gaps = 23/406 (5%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYAS-----SRGHQNVLLM 543
D+ G TAL A+ G IVE LL+ G+E+N D++ +AL A+ S+GH +V+ +
Sbjct: 334 DNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSL 393
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L+ GA ++ + D TPL +A GH+ V ++ G +++ + +G TPL
Sbjct: 394 LIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLL----EGGA--DVDHTDNNGRTPLLA 447
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
A+ G+ + L+ G+ +S +T A ++V+++ + H +
Sbjct: 448 AASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAG 507
Query: 664 VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAIS--YGDVKLACFYM 721
+ + + L + L + + TN+ I+N I IL + Y V++
Sbjct: 508 WTPLHMAAFEGHRLICEALIEQGARTNE----IDNDGRIPFILASQEGHYDCVQILLENK 563
Query: 722 -NIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGL 780
NID + + N+L E + DVN D++G L+ A
Sbjct: 564 SNIDQRGY-----DGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQ 618
Query: 781 DEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHD 840
+ N ANV + + +T LH++ ++++L+ A++NA D + + L
Sbjct: 619 LTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQS 678
Query: 841 ASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
A+ G++ ++L+ + + TAL +A + H+ ++ ++
Sbjct: 679 AAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 724
Score = 87.4 bits (207), Expect = 2e-16
Identities = 91/374 (24%), Positives = 169/374 (45%), Gaps = 24/374 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G+T L VA+ G +V+ LLE G++++ TD N + L A+S GH +V+ LL G
Sbjct: 405 DKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWG 464
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + + T L +A G++ V+ ++ R ++ N +++G TPLH+A+ G
Sbjct: 465 AAVDSIDSEGRTVLSIASAQGNVEVVRTLL------DRGLDENHRDDAGWTPLHMAAFEG 518
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAH---NLRILQVLKSCTPNLFEYIHITSSEVK 665
+ I LIE G+ + ++ + F A + +Q+L N+ + + + ++
Sbjct: 519 HRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALR 578
Query: 666 KISCESEKP--TSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNI 723
+ E + L + C D D T+ L L ++ A + +
Sbjct: 579 VAALEGHRDIVELLFSHGADVNCKDA-DGRPTLYILALENQLTMAEYF-----------L 626
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKR-KTESCTDFDVNVCDSNGFTALHYAARYGLDE 782
+ A + + + H C + + + DVN D+ +AL AA G +
Sbjct: 627 ENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVK 686
Query: 783 FCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDAS 842
+LI + A V+ + T L +AA V+++LL++GA+ N D T + A+
Sbjct: 687 VVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAA 746
Query: 843 ETGNIGAAKILLSY 856
+ G+ K+L Y
Sbjct: 747 KNGHSQIIKLLEKY 760
Score = 80.2 bits (189), Expect = 3e-14
Identities = 52/203 (25%), Positives = 107/203 (52%), Gaps = 7/203 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ G L++ ++ + T+ E LE G+ + A+D +ALH + +GH ++ +L+
Sbjct: 602 KDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAY 661
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A++N + +K + L A GH+ V+ +I EH G ++ C G T L +A++
Sbjct: 662 HADVNAADNEKRSALQSAAWQGHVKVVQLLI---EH-GAVVDHTC--NQGATALCIAAQE 715
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH-ITSSEVKK 666
G+ + ++L+EHG++P+ + + +TA A Q++K ++ + S V
Sbjct: 716 GHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLNGCSPSPVHT 775
Query: 667 ISCESEKPTSLKLQNLTLKCSDT 689
+ + + S K+Q+LT+K + +
Sbjct: 776 MEQKPLQSLSSKVQSLTIKSNSS 798
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/142 (31%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
S DS G T L +AS G +V TLL+ G + N D + LH A+ GH+ + L+
Sbjct: 469 SIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIE 528
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA N+ + D P LA GH CV+ ++ K NI+ G L +A+
Sbjct: 529 QGARTNEIDNDGRIPFILASQEGHYDCVQILL------ENKSNIDQRGYDGRNALRVAAL 582
Query: 607 WGYEGIARLLIEHGSEPSLQNS 628
G+ I LL HG++ + +++
Sbjct: 583 EGHRDIVELLFSHGADVNCKDA 604
Score = 74.5 bits (175), Expect = 1e-12
Identities = 45/145 (31%), Positives = 74/145 (51%), Gaps = 6/145 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
DS+G T L A+ G +V L+ G+++ D + + L A+ +GH V+ L+ G
Sbjct: 202 DSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCG 261
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
ANIN + D T L A GH V A++Y + ++CA+ T L A+ G
Sbjct: 262 ANINHTDQDGWTALRSAAWGGHTEVVSALLYAG------VKVDCADADSRTVLRAAAWGG 315
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTA 633
+E I L++HG+E + ++ +TA
Sbjct: 316 HEDIVLNLLQHGAEVNKADNEGRTA 340
Score = 72.1 bits (169), Expect = 8e-12
Identities = 46/149 (30%), Positives = 75/149 (50%), Gaps = 6/149 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D+HG T L +A+ G +V L+ G+ IN TD + +AL A+ GH V+ LL++G
Sbjct: 235 DAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAG 294
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ + D T L A GH V ++ +H +N A+ G T L A+ G
Sbjct: 295 VKVDCADADSRTVLRAAAWGGHEDIVLNLL---QHGAE---VNKADNEGRTALIAAAYMG 348
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ I L++HG+E + ++ +TA A
Sbjct: 349 HREIVEHLLDHGAEVNHEDVDGRTALSVA 377
Score = 65.7 bits (153), Expect = 7e-10
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 6/134 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
R G AL VA++ G IVE L G+++N D + L+ + + L +
Sbjct: 569 RGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLEN 628
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GAN+ + + T LH++ GH+ V+ +I A H+ ++N A+ + L A+
Sbjct: 629 GANVEASDAEGRTALHVSCWQGHMEMVQVLI--AYHA----DVNAADNEKRSALQSAAWQ 682
Query: 608 GYEGIARLLIEHGS 621
G+ + +LLIEHG+
Sbjct: 683 GHVKVVQLLIEHGA 696
Score = 64.1 bits (149), Expect = 2e-09
Identities = 40/136 (29%), Positives = 67/136 (49%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V D+ G TALH + G E +LI A+VN + + ++ L AA V++L
Sbjct: 631 NVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQL 690
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+++GA ++ T L A++ G+I ++LL + D + +TA+ VA H
Sbjct: 691 LIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGH 750
Query: 880 LTIIDLIDNYANKYAN 895
II L++ Y N
Sbjct: 751 SQIIKLLEKYGASSLN 766
Score = 62.1 bits (144), Expect = 8e-09
Identities = 42/139 (30%), Positives = 70/139 (50%), Gaps = 11/139 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D+ T L A+ G IV LL+ G+E+N D +AL A+ GH+ ++ LL G
Sbjct: 301 DADSRTVLRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHG 360
Query: 549 ANINQKNIDKNTPLHLAV-----NNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
A +N +++D T L +A + GH V +I R ++ ++ G TPL +
Sbjct: 361 AEVNHEDVDGRTALSVAALCVPASKGHASVVSLLI------DRGAEVDHCDKDGMTPLLV 414
Query: 604 ASKWGYEGIARLLIEHGSE 622
A+ G+ + LL+E G++
Sbjct: 415 AAYEGHVDVVDLLLEGGAD 433
Score = 61.3 bits (142), Expect = 1e-08
Identities = 42/123 (34%), Positives = 56/123 (45%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN CDSNG T L AA G + N+L+ A++ + TPL LAA T V+ L
Sbjct: 198 VNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCL 257
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ GANIN D T L A+ G+ LL + +A +T L A H
Sbjct: 258 IGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTVLRAAAWGGHE 317
Query: 881 TII 883
I+
Sbjct: 318 DIV 320
Score = 58.8 bits (136), Expect = 8e-08
Identities = 40/139 (28%), Positives = 68/139 (48%), Gaps = 11/139 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G TAL A+ G +V LL G +++ D + + L A+ GH++++L LL G
Sbjct: 268 DQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTVLRAAAWGGHEDIVLNLLQHG 327
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA---- 604
A +N+ + + T L A GH V+ ++ +H +N + G T L +A
Sbjct: 328 AEVNKADNEGRTALIAAAYMGHREIVEHLL---DHGA---EVNHEDVDGRTALSVAALCV 381
Query: 605 -SKWGYEGIARLLIEHGSE 622
+ G+ + LLI+ G+E
Sbjct: 382 PASKGHASVVSLLIDRGAE 400
Score = 54.8 bits (126), Expect = 1e-06
Identities = 37/132 (28%), Positives = 65/132 (49%), Gaps = 5/132 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
++N D +G+TAL AA G E + L++ V+C + ++T L AA ++
Sbjct: 263 NINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTVLRAAAWGGHEDIVLN 322
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA----- 874
LL +GA +N D T L A+ G+ + LL + ++ + +TAL+VA
Sbjct: 323 LLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVP 382
Query: 875 KDKVHLTIIDLI 886
K H +++ L+
Sbjct: 383 ASKGHASVVSLL 394
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ + D++G T L AAR G + N LI AN+N ++ T L AA T V+
Sbjct: 230 DLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSA 289
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL G ++ D T L A+ G+ LL + ++ + +TAL A H
Sbjct: 290 LLYAGVKVDCADADSRTVLRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGH 349
Query: 880 LTIID-LIDNYA 890
I++ L+D+ A
Sbjct: 350 REIVEHLLDHGA 361
Score = 54.4 bits (125), Expect = 2e-06
Identities = 38/132 (28%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAI-----NNKT 814
+VN D+ G TAL AA G E L+ + A VN + +T L +AA+
Sbjct: 329 EVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHA 388
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V+ LL+D GA ++ D TPL A+ G++ +LL D+ + +T L A
Sbjct: 389 SVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAA 448
Query: 875 KDKVHLTIIDLI 886
H ++++ +
Sbjct: 449 ASMGHASVVNTL 460
Score = 53.6 bits (123), Expect = 3e-06
Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DV+ D+NG T L AA G N L+F A V+ + + +T L +A+ V+R
Sbjct: 433 DVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRT 492
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LLD G + N D A TPLH A+ G+ + L+ ++ + +A + H
Sbjct: 493 LLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGH 552
Query: 880 LTIID-LIDNYAN 891
+ L++N +N
Sbjct: 553 YDCVQILLENKSN 565
Score = 51.2 bits (117), Expect = 2e-05
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 6/113 (5%)
Query: 508 VETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVN 567
+ TLL+ G+ +N D N + L A+ G +V+ +L+ GA++ ++ +TPL LA
Sbjct: 188 IRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAAR 247
Query: 568 NGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHG 620
GH V +I G NIN ++ G T L A+ G+ + L+ G
Sbjct: 248 QGHTKVVNCLI------GCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAG 294
Score = 50.0 bits (114), Expect = 4e-05
Identities = 27/93 (29%), Positives = 49/93 (52%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D+ +AL A+ G +V+ L+E G+ ++ T +AL A+ GH +V+ +L
Sbjct: 665 VNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 724
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAI 577
L GA+ N + T + +A NGH +K +
Sbjct: 725 LEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 757
Score = 48.0 bits (109), Expect = 1e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 1/137 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N D G+T LH AA G C LI A N + + P LA+ +++
Sbjct: 499 DENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQI 558
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+N +NI+ L A+ G+ ++L S+ D+ +A + L + +
Sbjct: 559 LLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQ 618
Query: 880 LTIID-LIDNYANKYAN 895
LT+ + ++N AN A+
Sbjct: 619 LTMAEYFLENGANVEAS 635
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/105 (26%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Query: 782 EFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDA 841
E +L+ A+VN + + + A + IR LLDNGA++N D T L +A
Sbjct: 155 EVLQLLVKAGAHVNSEDDRTSCIVRQALEREDS--IRTLLDNGASVNQCDSNGRTLLANA 212
Query: 842 SETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+ +G++ +L+S D+ + +A T L +A + H +++ +
Sbjct: 213 AYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCL 257
Score = 37.5 bits (83), Expect = 0.21
Identities = 27/100 (27%), Positives = 45/100 (45%)
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
L+ N A+VN + +T L AA + V+ LL+ GA++ D +TPL A+ G+
Sbjct: 191 LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGH 250
Query: 847 IGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
L+ +I + TAL A H ++ +
Sbjct: 251 TKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSAL 290
>DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 87.4 bits (207), Expect = 2e-16
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G TALH+A A ++ +LL G++I +ALH A+ GH +LL GAN
Sbjct: 100 NGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGAN 159
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N ++ TPLH+A GH + ++ F ++N + E G+ PLHLAS G+
Sbjct: 160 VNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG------ADVNVSGEVGDRPLHLASAKGFL 213
Query: 611 GIARLLIEHGSE 622
IA+LL+E GS+
Sbjct: 214 NIAKLLMEEGSK 225
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/148 (33%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLTALH+A+I G + LL+ G+ +N D + LH A+ GH+ V +LL GA++
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + PLHLA G L+ K ++ G K ++N + + PLH S++G+
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLM----EEGSKADVNAQDNEDHVPLHFCSRFGHHD 249
Query: 612 IARLLIEHGSE--PSLQNSYHKTAFDYA 637
I + L++ E P + N Y T A
Sbjct: 250 IVKYLLQSDLEVQPHVVNIYGDTPLHLA 277
Score = 74.9 bits (176), Expect = 1e-12
Identities = 45/136 (33%), Positives = 73/136 (53%), Gaps = 7/136 (5%)
Query: 488 RDSHGLTALHVASI-HGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
R +GL+ LH+ I GK + + TL+ G + N +ALH A + + ++ LLH
Sbjct: 63 RTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLH 122
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
SGA+I Q T LH+A GHL ++ +H N+N + TPLH+A+
Sbjct: 123 SGADIQQVGYGGLTALHIATIAGHLEAADVLL---QHGA---NVNIQDAVFFTPLHIAAY 176
Query: 607 WGYEGIARLLIEHGSE 622
+G+E + RLL++ G++
Sbjct: 177 YGHEQVTRLLLKFGAD 192
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/154 (29%), Positives = 81/154 (52%), Gaps = 8/154 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH+A+ +G + LL+ G+++N + LH AS++G N+ +L+
Sbjct: 163 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 222
Query: 548 G--ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
G A++N ++ + + PLH GH VK ++ S ++ + N G+TPLHLA
Sbjct: 223 GSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL----QSDLEVQPHVVNIYGDTPLHLAC 278
Query: 606 KWGYEGIARLLIEHGSEPSL--QNSYHKTAFDYA 637
G +A+ +I+ SL +N + +TAF A
Sbjct: 279 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 312
Score = 63.3 bits (147), Expect = 4e-09
Identities = 37/95 (38%), Positives = 51/95 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ G TALH A G E ++L+ + ANVN ++ TPLH+AA V RL
Sbjct: 126 DIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRL 185
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
LL GA++N + PLH AS G + AK+L+
Sbjct: 186 LLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Query: 734 EKSNSLCHPLCECQYCKR--KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
E SL H C C K +T + NGFTALH A E L+ +
Sbjct: 65 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++ T LH+A I +LL +GAN+N D TPLH A+ G+ +
Sbjct: 125 ADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTR 184
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANK 892
+LL + D+ + L +A K L I L+ +K
Sbjct: 185 LLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSK 225
Score = 60.5 bits (140), Expect = 3e-08
Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ D+ FT LH AA YG ++ +L+ A+VN + PLHLA+ + +L
Sbjct: 159 NVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKL 218
Query: 820 LLDNG--ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
L++ G A++NA D + PLH S G+ K LL + ++
Sbjct: 219 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEV 261
Score = 42.3 bits (95), Expect = 0.007
Identities = 36/145 (24%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEI--NATDLNECSALHYASSRGHQNVLL 542
+ ++D+ LH S G IV+ LL+ E+ + ++ + LH A G V
Sbjct: 228 VNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 287
Query: 543 MLLH-SGA-NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
++ SG ++ ++NI T H A G + + + + + ININ G+T
Sbjct: 288 EIIQISGTESLTKENIFSETAFHSACTYGK--SIDLVKFLLDQN--VININHQGRDGHTG 343
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL 625
LH A G+ + + L+++G++ +L
Sbjct: 344 LHSACYHGHIRLVQFLLDNGADMNL 368
Score = 40.7 bits (91), Expect = 0.022
Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCN--ILIFNRANVNCRNKKAQTPLHLAAIN 811
+S + +V + G T LH A G E I I ++ N ++T H A
Sbjct: 256 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTY 315
Query: 812 NKTV-VIRLLLD-NGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL------ 863
K++ +++ LLD N NIN +T LH A G+I + LL D+ L+
Sbjct: 316 GKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSR 375
Query: 864 ---NATEKTALAVAKDKVHLTIIDLIDNY 889
E+T L A +K H I+ L+ +Y
Sbjct: 376 SSGEKDEQTCLMWAYEKGHDAIVTLLKHY 404
Score = 33.5 bits (73), Expect = 3.4
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Query: 789 FNRANVNCRNKKAQTPLHLAAI-NNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
F++ N+N R + + LHL I K IR L+ G + + T LH A N
Sbjct: 55 FSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNA 114
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL DI + TAL +A HL D++
Sbjct: 115 ELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVL 153
>BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein
protein.
Length = 714
Score = 87.4 bits (207), Expect = 2e-16
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G TALH+A A ++ +LL G++I +ALH A+ GH +LL GAN
Sbjct: 218 NGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGAN 277
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N ++ TPLH+A GH + ++ F ++N + E G+ PLHLAS G+
Sbjct: 278 VNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG------ADVNVSGEVGDRPLHLASAKGFL 331
Query: 611 GIARLLIEHGSE 622
IA+LL+E GS+
Sbjct: 332 NIAKLLMEEGSK 343
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/148 (32%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLTALH+A+I G + LL+ G+ +N D + LH A+ GH+ V +LL GA++
Sbjct: 252 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 311
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + PLHLA G L+ K ++ G K ++N + + PLH S++G+
Sbjct: 312 NVSGEVGDRPLHLASAKGFLNIAKLLM----EEGSKADVNAQDNEDHVPLHFCSRFGHHD 367
Query: 612 IARLLIEHGSE--PSLQNSYHKTAFDYA 637
+ + L++ E P + N Y T A
Sbjct: 368 MVKYLLQSDLEVQPHVVNIYGDTPLHLA 395
Score = 74.9 bits (176), Expect = 1e-12
Identities = 45/136 (33%), Positives = 73/136 (53%), Gaps = 7/136 (5%)
Query: 488 RDSHGLTALHVASI-HGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
R +GL+ LH+ I GK + + TL+ G + N +ALH A + + ++ LLH
Sbjct: 181 RTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLH 240
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
SGA+I Q T LH+A GHL ++ +H N+N + TPLH+A+
Sbjct: 241 SGADIQQVGYGGLTALHIATIAGHLEAADVLL---QHGA---NVNIQDAVFFTPLHIAAY 294
Query: 607 WGYEGIARLLIEHGSE 622
+G+E + RLL++ G++
Sbjct: 295 YGHEQVTRLLLKFGAD 310
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/154 (29%), Positives = 81/154 (52%), Gaps = 8/154 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH+A+ +G + LL+ G+++N + LH AS++G N+ +L+
Sbjct: 281 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 340
Query: 548 G--ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
G A++N ++ + + PLH GH VK ++ S ++ + N G+TPLHLA
Sbjct: 341 GSKADVNAQDNEDHVPLHFCSRFGHHDMVKYLL----QSDLEVQPHVVNIYGDTPLHLAC 396
Query: 606 KWGYEGIARLLIEHGSEPSL--QNSYHKTAFDYA 637
G +A+ +I+ SL +N + +TAF A
Sbjct: 397 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 430
Score = 63.3 bits (147), Expect = 4e-09
Identities = 37/95 (38%), Positives = 51/95 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ G TALH A G E ++L+ + ANVN ++ TPLH+AA V RL
Sbjct: 244 DIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRL 303
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
LL GA++N + PLH AS G + AK+L+
Sbjct: 304 LLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 338
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Query: 734 EKSNSLCHPLCECQYCKR--KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
E SL H C C K +T + NGFTALH A E L+ +
Sbjct: 183 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 242
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++ T LH+A I +LL +GAN+N D TPLH A+ G+ +
Sbjct: 243 ADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTR 302
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANK 892
+LL + D+ + L +A K L I L+ +K
Sbjct: 303 LLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSK 343
Score = 60.5 bits (140), Expect = 3e-08
Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ D+ FT LH AA YG ++ +L+ A+VN + PLHLA+ + +L
Sbjct: 277 NVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKL 336
Query: 820 LLDNG--ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
L++ G A++NA D + PLH S G+ K LL + ++
Sbjct: 337 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDMVKYLLQSDLEV 379
Score = 42.3 bits (95), Expect = 0.007
Identities = 36/145 (24%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEI--NATDLNECSALHYASSRGHQNVLL 542
+ ++D+ LH S G +V+ LL+ E+ + ++ + LH A G V
Sbjct: 346 VNAQDNEDHVPLHFCSRFGHHDMVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 405
Query: 543 MLLH-SGA-NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
++ SG ++ ++NI T H A G + + + + + ININ G+T
Sbjct: 406 EIIQISGTESLTKENIFSETAFHSACTYGK--SIDLVKFLLDQN--VININHQGRDGHTG 461
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL 625
LH A G+ + + L+++G++ SL
Sbjct: 462 LHSACYHGHIRLVQFLLDNGADMSL 486
Score = 41.1 bits (92), Expect = 0.017
Identities = 42/149 (28%), Positives = 66/149 (44%), Gaps = 13/149 (8%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCN--ILIFNRANVNCRNKKAQTPLHLAAIN 811
+S + +V + G T LH A G E I I ++ N ++T H A
Sbjct: 374 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTY 433
Query: 812 NKTV-VIRLLLD-NGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL------ 863
K++ +++ LLD N NIN +T LH A G+I + LL D++L+
Sbjct: 434 GKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMSLVACDPSR 493
Query: 864 ---NATEKTALAVAKDKVHLTIIDLIDNY 889
E+T L A +K H I+ L+ +Y
Sbjct: 494 SSGEKDEQTCLMWAYEKGHDAIVTLLKHY 522
Score = 33.5 bits (73), Expect = 3.4
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Query: 789 FNRANVNCRNKKAQTPLHLAAI-NNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
F++ N+N R + + LHL I K IR L+ G + + T LH A N
Sbjct: 173 FSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNA 232
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL DI + TAL +A HL D++
Sbjct: 233 ELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVL 271
>BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 87.4 bits (207), Expect = 2e-16
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G TALH+A A ++ +LL G++I +ALH A+ GH +LL GAN
Sbjct: 100 NGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGAN 159
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N ++ TPLH+A GH + ++ F ++N + E G+ PLHLAS G+
Sbjct: 160 VNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG------ADVNVSGEVGDRPLHLASAKGFL 213
Query: 611 GIARLLIEHGSE 622
IA+LL+E GS+
Sbjct: 214 NIAKLLMEEGSK 225
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/148 (33%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLTALH+A+I G + LL+ G+ +N D + LH A+ GH+ V +LL GA++
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + PLHLA G L+ K ++ G K ++N + + PLH S++G+
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLM----EEGSKADVNAQDNEDHVPLHFCSRFGHHD 249
Query: 612 IARLLIEHGSE--PSLQNSYHKTAFDYA 637
I + L++ E P + N Y T A
Sbjct: 250 IVKYLLQSDLEVQPHVVNIYGDTPLHLA 277
Score = 74.9 bits (176), Expect = 1e-12
Identities = 45/136 (33%), Positives = 73/136 (53%), Gaps = 7/136 (5%)
Query: 488 RDSHGLTALHVASI-HGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
R +GL+ LH+ I GK + + TL+ G + N +ALH A + + ++ LLH
Sbjct: 63 RTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLH 122
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
SGA+I Q T LH+A GHL ++ +H N+N + TPLH+A+
Sbjct: 123 SGADIQQVGYGGLTALHIATIAGHLEAADVLL---QHGA---NVNIQDAVFFTPLHIAAY 176
Query: 607 WGYEGIARLLIEHGSE 622
+G+E + RLL++ G++
Sbjct: 177 YGHEQVTRLLLKFGAD 192
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/154 (29%), Positives = 81/154 (52%), Gaps = 8/154 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH+A+ +G + LL+ G+++N + LH AS++G N+ +L+
Sbjct: 163 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 222
Query: 548 G--ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
G A++N ++ + + PLH GH VK ++ S ++ + N G+TPLHLA
Sbjct: 223 GSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL----QSDLEVQPHVVNIYGDTPLHLAC 278
Query: 606 KWGYEGIARLLIEHGSEPSL--QNSYHKTAFDYA 637
G +A+ +I+ SL +N + +TAF A
Sbjct: 279 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 312
Score = 63.3 bits (147), Expect = 4e-09
Identities = 37/95 (38%), Positives = 51/95 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ G TALH A G E ++L+ + ANVN ++ TPLH+AA V RL
Sbjct: 126 DIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRL 185
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
LL GA++N + PLH AS G + AK+L+
Sbjct: 186 LLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Query: 734 EKSNSLCHPLCECQYCKR--KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
E SL H C C K +T + NGFTALH A E L+ +
Sbjct: 65 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++ T LH+A I +LL +GAN+N D TPLH A+ G+ +
Sbjct: 125 ADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTR 184
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANK 892
+LL + D+ + L +A K L I L+ +K
Sbjct: 185 LLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSK 225
Score = 60.5 bits (140), Expect = 3e-08
Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ D+ FT LH AA YG ++ +L+ A+VN + PLHLA+ + +L
Sbjct: 159 NVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKL 218
Query: 820 LLDNG--ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
L++ G A++NA D + PLH S G+ K LL + ++
Sbjct: 219 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEV 261
Score = 42.3 bits (95), Expect = 0.007
Identities = 36/145 (24%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEI--NATDLNECSALHYASSRGHQNVLL 542
+ ++D+ LH S G IV+ LL+ E+ + ++ + LH A G V
Sbjct: 228 VNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 287
Query: 543 MLLH-SGA-NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
++ SG ++ ++NI T H A G + + + + + ININ G+T
Sbjct: 288 EIIQISGTESLTKENIFSETAFHSACTYGK--SIDLVKFLLDQN--VININHQGRDGHTG 343
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL 625
LH A G+ + + L+++G++ +L
Sbjct: 344 LHSACYHGHIRLVQFLLDNGADMNL 368
Score = 40.7 bits (91), Expect = 0.022
Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCN--ILIFNRANVNCRNKKAQTPLHLAAIN 811
+S + +V + G T LH A G E I I ++ N ++T H A
Sbjct: 256 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTY 315
Query: 812 NKTV-VIRLLLD-NGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL------ 863
K++ +++ LLD N NIN +T LH A G+I + LL D+ L+
Sbjct: 316 GKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSR 375
Query: 864 ---NATEKTALAVAKDKVHLTIIDLIDNY 889
E+T L A +K H I+ L+ +Y
Sbjct: 376 SSGEKDEQTCLMWAYEKGHDAIVTLLKHY 404
Score = 33.5 bits (73), Expect = 3.4
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Query: 789 FNRANVNCRNKKAQTPLHLAAI-NNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
F++ N+N R + + LHL I K IR L+ G + + T LH A N
Sbjct: 55 FSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNA 114
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL DI + TAL +A HL D++
Sbjct: 115 ELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVL 153
>BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 87.4 bits (207), Expect = 2e-16
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G TALH+A A ++ +LL G++I +ALH A+ GH +LL GAN
Sbjct: 100 NGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGAN 159
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N ++ TPLH+A GH + ++ F ++N + E G+ PLHLAS G+
Sbjct: 160 VNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG------ADVNVSGEVGDRPLHLASAKGFL 213
Query: 611 GIARLLIEHGSE 622
IA+LL+E GS+
Sbjct: 214 NIAKLLMEEGSK 225
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/148 (33%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLTALH+A+I G + LL+ G+ +N D + LH A+ GH+ V +LL GA++
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + PLHLA G L+ K ++ G K ++N + + PLH S++G+
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLM----EEGSKADVNAQDNEDHVPLHFCSRFGHHD 249
Query: 612 IARLLIEHGSE--PSLQNSYHKTAFDYA 637
I + L++ E P + N Y T A
Sbjct: 250 IVKYLLQSDLEVQPHVVNIYGDTPLHLA 277
Score = 74.9 bits (176), Expect = 1e-12
Identities = 45/136 (33%), Positives = 73/136 (53%), Gaps = 7/136 (5%)
Query: 488 RDSHGLTALHVASI-HGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
R +GL+ LH+ I GK + + TL+ G + N +ALH A + + ++ LLH
Sbjct: 63 RTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLH 122
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
SGA+I Q T LH+A GHL ++ +H N+N + TPLH+A+
Sbjct: 123 SGADIQQVGYGGLTALHIATIAGHLEAADVLL---QHGA---NVNIQDAVFFTPLHIAAY 176
Query: 607 WGYEGIARLLIEHGSE 622
+G+E + RLL++ G++
Sbjct: 177 YGHEQVTRLLLKFGAD 192
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/154 (29%), Positives = 81/154 (52%), Gaps = 8/154 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH+A+ +G + LL+ G+++N + LH AS++G N+ +L+
Sbjct: 163 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 222
Query: 548 G--ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
G A++N ++ + + PLH GH VK ++ S ++ + N G+TPLHLA
Sbjct: 223 GSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL----QSDLEVQPHVVNIYGDTPLHLAC 278
Query: 606 KWGYEGIARLLIEHGSEPSL--QNSYHKTAFDYA 637
G +A+ +I+ SL +N + +TAF A
Sbjct: 279 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 312
Score = 63.3 bits (147), Expect = 4e-09
Identities = 37/95 (38%), Positives = 51/95 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ G TALH A G E ++L+ + ANVN ++ TPLH+AA V RL
Sbjct: 126 DIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRL 185
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
LL GA++N + PLH AS G + AK+L+
Sbjct: 186 LLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Query: 734 EKSNSLCHPLCECQYCKR--KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
E SL H C C K +T + NGFTALH A E L+ +
Sbjct: 65 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++ T LH+A I +LL +GAN+N D TPLH A+ G+ +
Sbjct: 125 ADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTR 184
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANK 892
+LL + D+ + L +A K L I L+ +K
Sbjct: 185 LLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSK 225
Score = 60.5 bits (140), Expect = 3e-08
Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ D+ FT LH AA YG ++ +L+ A+VN + PLHLA+ + +L
Sbjct: 159 NVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKL 218
Query: 820 LLDNG--ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
L++ G A++NA D + PLH S G+ K LL + ++
Sbjct: 219 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEV 261
Score = 42.3 bits (95), Expect = 0.007
Identities = 36/145 (24%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEI--NATDLNECSALHYASSRGHQNVLL 542
+ ++D+ LH S G IV+ LL+ E+ + ++ + LH A G V
Sbjct: 228 VNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 287
Query: 543 MLLH-SGA-NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
++ SG ++ ++NI T H A G + + + + + ININ G+T
Sbjct: 288 EIIQISGTESLTKENIFSETAFHSACTYGK--SIDLVKFLLDQN--VININHQGRDGHTG 343
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL 625
LH A G+ + + L+++G++ +L
Sbjct: 344 LHSACYHGHIRLVQFLLDNGADMNL 368
Score = 40.7 bits (91), Expect = 0.022
Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCN--ILIFNRANVNCRNKKAQTPLHLAAIN 811
+S + +V + G T LH A G E I I ++ N ++T H A
Sbjct: 256 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTY 315
Query: 812 NKTV-VIRLLLD-NGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL------ 863
K++ +++ LLD N NIN +T LH A G+I + LL D+ L+
Sbjct: 316 GKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSR 375
Query: 864 ---NATEKTALAVAKDKVHLTIIDLIDNY 889
E+T L A +K H I+ L+ +Y
Sbjct: 376 SSGEKDEQTCLMWAYEKGHDAIVTLLKHY 404
Score = 33.5 bits (73), Expect = 3.4
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Query: 789 FNRANVNCRNKKAQTPLHLAAI-NNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
F++ N+N R + + LHL I K IR L+ G + + T LH A N
Sbjct: 55 FSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNA 114
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL DI + TAL +A HL D++
Sbjct: 115 ELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVL 153
>BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 87.4 bits (207), Expect = 2e-16
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G TALH+A A ++ +LL G++I +ALH A+ GH +LL GAN
Sbjct: 100 NGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGAN 159
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N ++ TPLH+A GH + ++ F ++N + E G+ PLHLAS G+
Sbjct: 160 VNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG------ADVNVSGEVGDRPLHLASAKGFL 213
Query: 611 GIARLLIEHGSE 622
IA+LL+E GS+
Sbjct: 214 NIAKLLMEEGSK 225
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/148 (33%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLTALH+A+I G + LL+ G+ +N D + LH A+ GH+ V +LL GA++
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + PLHLA G L+ K ++ G K ++N + + PLH S++G+
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLM----EEGSKADVNAQDNEDHVPLHFCSRFGHHD 249
Query: 612 IARLLIEHGSE--PSLQNSYHKTAFDYA 637
I + L++ E P + N Y T A
Sbjct: 250 IVKYLLQSDLEVQPHVVNIYGDTPLHLA 277
Score = 74.9 bits (176), Expect = 1e-12
Identities = 45/136 (33%), Positives = 73/136 (53%), Gaps = 7/136 (5%)
Query: 488 RDSHGLTALHVASI-HGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
R +GL+ LH+ I GK + + TL+ G + N +ALH A + + ++ LLH
Sbjct: 63 RTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLH 122
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
SGA+I Q T LH+A GHL ++ +H N+N + TPLH+A+
Sbjct: 123 SGADIQQVGYGGLTALHIATIAGHLEAADVLL---QHGA---NVNIQDAVFFTPLHIAAY 176
Query: 607 WGYEGIARLLIEHGSE 622
+G+E + RLL++ G++
Sbjct: 177 YGHEQVTRLLLKFGAD 192
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/154 (29%), Positives = 81/154 (52%), Gaps = 8/154 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH+A+ +G + LL+ G+++N + LH AS++G N+ +L+
Sbjct: 163 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 222
Query: 548 G--ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
G A++N ++ + + PLH GH VK ++ S ++ + N G+TPLHLA
Sbjct: 223 GSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL----QSDLEVQPHVVNIYGDTPLHLAC 278
Query: 606 KWGYEGIARLLIEHGSEPSL--QNSYHKTAFDYA 637
G +A+ +I+ SL +N + +TAF A
Sbjct: 279 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 312
Score = 63.3 bits (147), Expect = 4e-09
Identities = 37/95 (38%), Positives = 51/95 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ G TALH A G E ++L+ + ANVN ++ TPLH+AA V RL
Sbjct: 126 DIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRL 185
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
LL GA++N + PLH AS G + AK+L+
Sbjct: 186 LLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Query: 734 EKSNSLCHPLCECQYCKR--KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
E SL H C C K +T + NGFTALH A E L+ +
Sbjct: 65 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++ T LH+A I +LL +GAN+N D TPLH A+ G+ +
Sbjct: 125 ADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTR 184
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANK 892
+LL + D+ + L +A K L I L+ +K
Sbjct: 185 LLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSK 225
Score = 60.5 bits (140), Expect = 3e-08
Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ D+ FT LH AA YG ++ +L+ A+VN + PLHLA+ + +L
Sbjct: 159 NVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKL 218
Query: 820 LLDNG--ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
L++ G A++NA D + PLH S G+ K LL + ++
Sbjct: 219 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEV 261
Score = 42.3 bits (95), Expect = 0.007
Identities = 36/145 (24%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEI--NATDLNECSALHYASSRGHQNVLL 542
+ ++D+ LH S G IV+ LL+ E+ + ++ + LH A G V
Sbjct: 228 VNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 287
Query: 543 MLLH-SGA-NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
++ SG ++ ++NI T H A G + + + + + ININ G+T
Sbjct: 288 EIIQISGTESLTKENIFSETAFHSACTYGK--SIDLVKFLLDQN--VININHQGRDGHTG 343
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL 625
LH A G+ + + L+++G++ +L
Sbjct: 344 LHSACYHGHIRLVQFLLDNGADMNL 368
Score = 40.7 bits (91), Expect = 0.022
Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCN--ILIFNRANVNCRNKKAQTPLHLAAIN 811
+S + +V + G T LH A G E I I ++ N ++T H A
Sbjct: 256 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTY 315
Query: 812 NKTV-VIRLLLD-NGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL------ 863
K++ +++ LLD N NIN +T LH A G+I + LL D+ L+
Sbjct: 316 GKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSR 375
Query: 864 ---NATEKTALAVAKDKVHLTIIDLIDNY 889
E+T L A +K H I+ L+ +Y
Sbjct: 376 SSGEKDEQTCLMWAYEKGHDAIVTLLKHY 404
Score = 33.5 bits (73), Expect = 3.4
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Query: 789 FNRANVNCRNKKAQTPLHLAAI-NNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
F++ N+N R + + LHL I K IR L+ G + + T LH A N
Sbjct: 55 FSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNA 114
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL DI + TAL +A HL D++
Sbjct: 115 ELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVL 153
>BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein.
Length = 743
Score = 87.4 bits (207), Expect = 2e-16
Identities = 91/374 (24%), Positives = 169/374 (45%), Gaps = 24/374 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G+T L VA+ G +V+ LLE G++++ TD N + L A+S GH +V+ LL G
Sbjct: 59 DKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWG 118
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A ++ + + T L +A G++ V+ ++ R ++ N +++G TPLH+A+ G
Sbjct: 119 AAVDSIDSEGRTVLSIASAQGNVEVVRTLL------DRGLDENHRDDAGWTPLHMAAFEG 172
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAH---NLRILQVLKSCTPNLFEYIHITSSEVK 665
+ I LIE G+ + ++ + F A + +Q+L N+ + + + ++
Sbjct: 173 HRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALR 232
Query: 666 KISCESEKP--TSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNI 723
+ E + L + C D D T+ L L ++ A + +
Sbjct: 233 VAALEGHRDIVELLFSHGADVNCKDA-DGRPTLYILALENQLTMAEYF-----------L 280
Query: 724 DYSAFIAPDKEKSNSLCHPLCECQYCKR-KTESCTDFDVNVCDSNGFTALHYAARYGLDE 782
+ A + + + H C + + + DVN D+ +AL AA G +
Sbjct: 281 ENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVK 340
Query: 783 FCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDAS 842
+LI + A V+ + T L +AA V+++LL++GA+ N D T + A+
Sbjct: 341 VVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAA 400
Query: 843 ETGNIGAAKILLSY 856
+ G+ K+L Y
Sbjct: 401 KNGHSQIIKLLEKY 414
Score = 81.0 bits (191), Expect = 2e-14
Identities = 87/392 (22%), Positives = 173/392 (44%), Gaps = 23/392 (5%)
Query: 503 GKATIVETLLEMGSEINATDLNECSALHYA-----SSRGHQNVLLMLLHSGANINQKNID 557
G IVE LL+ G+E+N D++ +AL A +S+GH +V+ +L+ GA ++ + D
Sbjct: 2 GHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKD 61
Query: 558 KNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLI 617
TPL +A GH+ V ++ G +++ + +G TPL A+ G+ + L+
Sbjct: 62 GMTPLLVAAYEGHVDVVDLLL----EGG--ADVDHTDNNGRTPLLAAASMGHASVVNTLL 115
Query: 618 EHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G+ +S +T A ++V+++ + H + + + + L
Sbjct: 116 FWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRL 175
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAIS--YGDVKLAC-FYMNIDYSAFIAPDKE 734
+ L + + TN+ I+N I IL + Y V++ NID + +
Sbjct: 176 ICEALIEQGARTNE----IDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGY-----D 226
Query: 735 KSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANV 794
N+L E + DVN D++G L+ A + N ANV
Sbjct: 227 GRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANV 286
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
+ + +T LH++ ++++L+ A++NA D + + L A+ G++ ++L+
Sbjct: 287 EASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLI 346
Query: 855 SYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+ + TAL +A + H+ ++ ++
Sbjct: 347 EHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 378
Score = 80.2 bits (189), Expect = 3e-14
Identities = 52/203 (25%), Positives = 107/203 (52%), Gaps = 7/203 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ G L++ ++ + T+ E LE G+ + A+D +ALH + +GH ++ +L+
Sbjct: 256 KDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAY 315
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A++N + +K + L A GH+ V+ +I EH G ++ C G T L +A++
Sbjct: 316 HADVNAADNEKRSALQSAAWQGHVKVVQLLI---EH-GAVVDHTC--NQGATALCIAAQE 369
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH-ITSSEVKK 666
G+ + ++L+EHG++P+ + + +TA A Q++K ++ + S V
Sbjct: 370 GHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLNGCSPSPVHT 429
Query: 667 ISCESEKPTSLKLQNLTLKCSDT 689
+ + + S K+Q+LT+K + +
Sbjct: 430 MEQKPLQSLSSKVQSLTIKSNSS 452
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/142 (31%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
S DS G T L +AS G +V TLL+ G + N D + LH A+ GH+ + L+
Sbjct: 123 SIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIE 182
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA N+ + D P LA GH CV+ ++ K NI+ G L +A+
Sbjct: 183 QGARTNEIDNDGRIPFILASQEGHYDCVQILL------ENKSNIDQRGYDGRNALRVAAL 236
Query: 607 WGYEGIARLLIEHGSEPSLQNS 628
G+ I LL HG++ + +++
Sbjct: 237 EGHRDIVELLFSHGADVNCKDA 258
Score = 65.7 bits (153), Expect = 7e-10
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 6/134 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
R G AL VA++ G IVE L G+++N D + L+ + + L +
Sbjct: 223 RGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLEN 282
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GAN+ + + T LH++ GH+ V+ +I A H+ ++N A+ + L A+
Sbjct: 283 GANVEASDAEGRTALHVSCWQGHMEMVQVLI--AYHA----DVNAADNEKRSALQSAAWQ 336
Query: 608 GYEGIARLLIEHGS 621
G+ + +LLIEHG+
Sbjct: 337 GHVKVVQLLIEHGA 350
Score = 64.1 bits (149), Expect = 2e-09
Identities = 40/136 (29%), Positives = 67/136 (49%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V D+ G TALH + G E +LI A+VN + + ++ L AA V++L
Sbjct: 285 NVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQL 344
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+++GA ++ T L A++ G+I ++LL + D + +TA+ VA H
Sbjct: 345 LIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGH 404
Query: 880 LTIIDLIDNYANKYAN 895
II L++ Y N
Sbjct: 405 SQIIKLLEKYGASSLN 420
Score = 61.7 bits (143), Expect = 1e-08
Identities = 39/137 (28%), Positives = 71/137 (51%), Gaps = 11/137 (8%)
Query: 489 DSHGLTALHVASI-----HGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
D G TAL VA++ G A++V L++ G+E++ D + + L A+ GH +V+ +
Sbjct: 21 DVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDL 80
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GA+++ + + TPL A + GH V ++++ ++ + G T L +
Sbjct: 81 LLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWG------AAVDSIDSEGRTVLSI 134
Query: 604 ASKWGYEGIARLLIEHG 620
AS G + R L++ G
Sbjct: 135 ASAQGNVEVVRTLLDRG 151
Score = 53.6 bits (123), Expect = 3e-06
Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DV+ D+NG T L AA G N L+F A V+ + + +T L +A+ V+R
Sbjct: 87 DVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRT 146
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LLD G + N D A TPLH A+ G+ + L+ ++ + +A + H
Sbjct: 147 LLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGH 206
Query: 880 LTIID-LIDNYAN 891
+ L++N +N
Sbjct: 207 YDCVQILLENKSN 219
Score = 50.0 bits (114), Expect = 4e-05
Identities = 27/93 (29%), Positives = 49/93 (52%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D+ +AL A+ G +V+ L+E G+ ++ T +AL A+ GH +V+ +L
Sbjct: 319 VNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 378
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAI 577
L GA+ N + T + +A NGH +K +
Sbjct: 379 LEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 411
Score = 48.0 bits (109), Expect = 1e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 1/137 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N D G+T LH AA G C LI A N + + P LA+ +++
Sbjct: 153 DENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQI 212
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+N +NI+ L A+ G+ ++L S+ D+ +A + L + +
Sbjct: 213 LLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQ 272
Query: 880 LTIID-LIDNYANKYAN 895
LT+ + ++N AN A+
Sbjct: 273 LTMAEYFLENGANVEAS 289
>AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat
kinase protein.
Length = 835
Score = 87.4 bits (207), Expect = 2e-16
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G TALH+A A ++ +LL G++I +ALH A+ GH +LL GAN
Sbjct: 100 NGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGAN 159
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N ++ TPLH+A GH + ++ F ++N + E G+ PLHLAS G+
Sbjct: 160 VNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG------ADVNVSGEVGDRPLHLASAKGFL 213
Query: 611 GIARLLIEHGSE 622
IA+LL+E GS+
Sbjct: 214 NIAKLLMEEGSK 225
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/148 (33%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLTALH+A+I G + LL+ G+ +N D + LH A+ GH+ V +LL GA++
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + PLHLA G L+ K ++ G K ++N + + PLH S++G+
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLM----EEGSKADVNAQDNEDHVPLHFCSRFGHHD 249
Query: 612 IARLLIEHGSE--PSLQNSYHKTAFDYA 637
I + L++ E P + N Y T A
Sbjct: 250 IVKYLLQSDLEVQPHVVNIYGDTPLHLA 277
Score = 74.9 bits (176), Expect = 1e-12
Identities = 45/136 (33%), Positives = 73/136 (53%), Gaps = 7/136 (5%)
Query: 488 RDSHGLTALHVASI-HGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
R +GL+ LH+ I GK + + TL+ G + N +ALH A + + ++ LLH
Sbjct: 63 RTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLH 122
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
SGA+I Q T LH+A GHL ++ +H N+N + TPLH+A+
Sbjct: 123 SGADIQQVGYGGLTALHIATIAGHLEAADVLL---QHGA---NVNIQDAVFFTPLHIAAY 176
Query: 607 WGYEGIARLLIEHGSE 622
+G+E + RLL++ G++
Sbjct: 177 YGHEQVTRLLLKFGAD 192
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/154 (29%), Positives = 81/154 (52%), Gaps = 8/154 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH+A+ +G + LL+ G+++N + LH AS++G N+ +L+
Sbjct: 163 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 222
Query: 548 G--ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
G A++N ++ + + PLH GH VK ++ S ++ + N G+TPLHLA
Sbjct: 223 GSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL----QSDLEVQPHVVNIYGDTPLHLAC 278
Query: 606 KWGYEGIARLLIEHGSEPSL--QNSYHKTAFDYA 637
G +A+ +I+ SL +N + +TAF A
Sbjct: 279 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 312
Score = 63.3 bits (147), Expect = 4e-09
Identities = 37/95 (38%), Positives = 51/95 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ G TALH A G E ++L+ + ANVN ++ TPLH+AA V RL
Sbjct: 126 DIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRL 185
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
LL GA++N + PLH AS G + AK+L+
Sbjct: 186 LLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Query: 734 EKSNSLCHPLCECQYCKR--KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
E SL H C C K +T + NGFTALH A E L+ +
Sbjct: 65 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++ T LH+A I +LL +GAN+N D TPLH A+ G+ +
Sbjct: 125 ADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTR 184
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANK 892
+LL + D+ + L +A K L I L+ +K
Sbjct: 185 LLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSK 225
Score = 60.5 bits (140), Expect = 3e-08
Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ D+ FT LH AA YG ++ +L+ A+VN + PLHLA+ + +L
Sbjct: 159 NVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKL 218
Query: 820 LLDNG--ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
L++ G A++NA D + PLH S G+ K LL + ++
Sbjct: 219 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEV 261
Score = 42.3 bits (95), Expect = 0.007
Identities = 36/145 (24%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEI--NATDLNECSALHYASSRGHQNVLL 542
+ ++D+ LH S G IV+ LL+ E+ + ++ + LH A G V
Sbjct: 228 VNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 287
Query: 543 MLLH-SGA-NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
++ SG ++ ++NI T H A G + + + + + ININ G+T
Sbjct: 288 EIIQISGTESLTKENIFSETAFHSACTYGK--SIDLVKFLLDQN--VININHQGRDGHTG 343
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL 625
LH A G+ + + L+++G++ +L
Sbjct: 344 LHSACYHGHIRLVQFLLDNGADMNL 368
Score = 40.7 bits (91), Expect = 0.022
Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCN--ILIFNRANVNCRNKKAQTPLHLAAIN 811
+S + +V + G T LH A G E I I ++ N ++T H A
Sbjct: 256 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTY 315
Query: 812 NKTV-VIRLLLD-NGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL------ 863
K++ +++ LLD N NIN +T LH A G+I + LL D+ L+
Sbjct: 316 GKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSR 375
Query: 864 ---NATEKTALAVAKDKVHLTIIDLIDNY 889
E+T L A +K H I+ L+ +Y
Sbjct: 376 SSGEKDEQTCLMWAYEKGHDAIVTLLKHY 404
Score = 33.5 bits (73), Expect = 3.4
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Query: 789 FNRANVNCRNKKAQTPLHLAAI-NNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
F++ N+N R + + LHL I K IR L+ G + + T LH A N
Sbjct: 55 FSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNA 114
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL DI + TAL +A HL D++
Sbjct: 115 ELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVL 153
>AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosine
kinase protein.
Length = 835
Score = 87.4 bits (207), Expect = 2e-16
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G TALH+A A ++ +LL G++I +ALH A+ GH +LL GAN
Sbjct: 100 NGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGAN 159
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N ++ TPLH+A GH + ++ F ++N + E G+ PLHLAS G+
Sbjct: 160 VNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG------ADVNVSGEVGDRPLHLASAKGFL 213
Query: 611 GIARLLIEHGSE 622
IA+LL+E GS+
Sbjct: 214 NIAKLLMEEGSK 225
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/148 (33%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLTALH+A+I G + LL+ G+ +N D + LH A+ GH+ V +LL GA++
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + PLHLA G L+ K ++ G K ++N + + PLH S++G+
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLM----EEGSKADVNAQDNEDHVPLHFCSRFGHHD 249
Query: 612 IARLLIEHGSE--PSLQNSYHKTAFDYA 637
I + L++ E P + N Y T A
Sbjct: 250 IVKYLLQSDLEVQPHVVNIYGDTPLHLA 277
Score = 74.9 bits (176), Expect = 1e-12
Identities = 45/136 (33%), Positives = 73/136 (53%), Gaps = 7/136 (5%)
Query: 488 RDSHGLTALHVASI-HGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
R +GL+ LH+ I GK + + TL+ G + N +ALH A + + ++ LLH
Sbjct: 63 RTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLH 122
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
SGA+I Q T LH+A GHL ++ +H N+N + TPLH+A+
Sbjct: 123 SGADIQQVGYGGLTALHIATIAGHLEAADVLL---QHGA---NVNIQDAVFFTPLHIAAY 176
Query: 607 WGYEGIARLLIEHGSE 622
+G+E + RLL++ G++
Sbjct: 177 YGHEQVTRLLLKFGAD 192
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/154 (29%), Positives = 81/154 (52%), Gaps = 8/154 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH+A+ +G + LL+ G+++N + LH AS++G N+ +L+
Sbjct: 163 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 222
Query: 548 G--ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
G A++N ++ + + PLH GH VK ++ S ++ + N G+TPLHLA
Sbjct: 223 GSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL----QSDLEVQPHVVNIYGDTPLHLAC 278
Query: 606 KWGYEGIARLLIEHGSEPSL--QNSYHKTAFDYA 637
G +A+ +I+ SL +N + +TAF A
Sbjct: 279 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 312
Score = 63.3 bits (147), Expect = 4e-09
Identities = 37/95 (38%), Positives = 51/95 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ G TALH A G E ++L+ + ANVN ++ TPLH+AA V RL
Sbjct: 126 DIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRL 185
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
LL GA++N + PLH AS G + AK+L+
Sbjct: 186 LLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Query: 734 EKSNSLCHPLCECQYCKR--KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
E SL H C C K +T + NGFTALH A E L+ +
Sbjct: 65 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++ T LH+A I +LL +GAN+N D TPLH A+ G+ +
Sbjct: 125 ADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTR 184
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANK 892
+LL + D+ + L +A K L I L+ +K
Sbjct: 185 LLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSK 225
Score = 60.5 bits (140), Expect = 3e-08
Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ D+ FT LH AA YG ++ +L+ A+VN + PLHLA+ + +L
Sbjct: 159 NVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKL 218
Query: 820 LLDNG--ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
L++ G A++NA D + PLH S G+ K LL + ++
Sbjct: 219 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEV 261
Score = 42.3 bits (95), Expect = 0.007
Identities = 36/145 (24%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEI--NATDLNECSALHYASSRGHQNVLL 542
+ ++D+ LH S G IV+ LL+ E+ + ++ + LH A G V
Sbjct: 228 VNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 287
Query: 543 MLLH-SGA-NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
++ SG ++ ++NI T H A G + + + + + ININ G+T
Sbjct: 288 EIIQISGTESLTKENIFSETAFHSACTYGK--SIDLVKFLLDQN--VININHQGRDGHTG 343
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL 625
LH A G+ + + L+++G++ +L
Sbjct: 344 LHSACYHGHIRLVQFLLDNGADMNL 368
Score = 40.7 bits (91), Expect = 0.022
Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCN--ILIFNRANVNCRNKKAQTPLHLAAIN 811
+S + +V + G T LH A G E I I ++ N ++T H A
Sbjct: 256 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTY 315
Query: 812 NKTV-VIRLLLD-NGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL------ 863
K++ +++ LLD N NIN +T LH A G+I + LL D+ L+
Sbjct: 316 GKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSR 375
Query: 864 ---NATEKTALAVAKDKVHLTIIDLIDNY 889
E+T L A +K H I+ L+ +Y
Sbjct: 376 SSGEKDEQTCLMWAYEKGHDAIVTLLKHY 404
Score = 33.5 bits (73), Expect = 3.4
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Query: 789 FNRANVNCRNKKAQTPLHLAAI-NNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
F++ N+N R + + LHL I K IR L+ G + + T LH A N
Sbjct: 55 FSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNA 114
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL DI + TAL +A HL D++
Sbjct: 115 ELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVL 153
>AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinase
variant protein.
Length = 941
Score = 87.4 bits (207), Expect = 2e-16
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G TALH+A A ++ +LL G++I +ALH A+ GH +LL GAN
Sbjct: 206 NGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGAN 265
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N ++ TPLH+A GH + ++ F ++N + E G+ PLHLAS G+
Sbjct: 266 VNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG------ADVNVSGEVGDRPLHLASAKGFL 319
Query: 611 GIARLLIEHGSE 622
IA+LL+E GS+
Sbjct: 320 NIAKLLMEEGSK 331
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/148 (33%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLTALH+A+I G + LL+ G+ +N D + LH A+ GH+ V +LL GA++
Sbjct: 240 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 299
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + PLHLA G L+ K ++ G K ++N + + PLH S++G+
Sbjct: 300 NVSGEVGDRPLHLASAKGFLNIAKLLM----EEGSKADVNAQDNEDHVPLHFCSRFGHHD 355
Query: 612 IARLLIEHGSE--PSLQNSYHKTAFDYA 637
I + L++ E P + N Y T A
Sbjct: 356 IVKYLLQSDLEVQPHVVNIYGDTPLHLA 383
Score = 74.9 bits (176), Expect = 1e-12
Identities = 45/136 (33%), Positives = 73/136 (53%), Gaps = 7/136 (5%)
Query: 488 RDSHGLTALHVASI-HGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
R +GL+ LH+ I GK + + TL+ G + N +ALH A + + ++ LLH
Sbjct: 169 RTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLH 228
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
SGA+I Q T LH+A GHL ++ +H N+N + TPLH+A+
Sbjct: 229 SGADIQQVGYGGLTALHIATIAGHLEAADVLL---QHGA---NVNIQDAVFFTPLHIAAY 282
Query: 607 WGYEGIARLLIEHGSE 622
+G+E + RLL++ G++
Sbjct: 283 YGHEQVTRLLLKFGAD 298
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/154 (29%), Positives = 81/154 (52%), Gaps = 8/154 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH+A+ +G + LL+ G+++N + LH AS++G N+ +L+
Sbjct: 269 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 328
Query: 548 G--ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
G A++N ++ + + PLH GH VK ++ S ++ + N G+TPLHLA
Sbjct: 329 GSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL----QSDLEVQPHVVNIYGDTPLHLAC 384
Query: 606 KWGYEGIARLLIEHGSEPSL--QNSYHKTAFDYA 637
G +A+ +I+ SL +N + +TAF A
Sbjct: 385 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 418
Score = 63.3 bits (147), Expect = 4e-09
Identities = 37/95 (38%), Positives = 51/95 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ G TALH A G E ++L+ + ANVN ++ TPLH+AA V RL
Sbjct: 232 DIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRL 291
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
LL GA++N + PLH AS G + AK+L+
Sbjct: 292 LLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 326
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Query: 734 EKSNSLCHPLCECQYCKR--KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
E SL H C C K +T + NGFTALH A E L+ +
Sbjct: 171 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 230
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++ T LH+A I +LL +GAN+N D TPLH A+ G+ +
Sbjct: 231 ADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTR 290
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANK 892
+LL + D+ + L +A K L I L+ +K
Sbjct: 291 LLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSK 331
Score = 60.5 bits (140), Expect = 3e-08
Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ D+ FT LH AA YG ++ +L+ A+VN + PLHLA+ + +L
Sbjct: 265 NVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKL 324
Query: 820 LLDNG--ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
L++ G A++NA D + PLH S G+ K LL + ++
Sbjct: 325 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEV 367
Score = 42.3 bits (95), Expect = 0.007
Identities = 36/145 (24%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEI--NATDLNECSALHYASSRGHQNVLL 542
+ ++D+ LH S G IV+ LL+ E+ + ++ + LH A G V
Sbjct: 334 VNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 393
Query: 543 MLLH-SGA-NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
++ SG ++ ++NI T H A G + + + + + ININ G+T
Sbjct: 394 EIIQISGTESLTKENIFSETAFHSACTYGK--SIDLVKFLLDQN--VININHQGRDGHTG 449
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL 625
LH A G+ + + L+++G++ +L
Sbjct: 450 LHSACYHGHIRLVQFLLDNGADMNL 474
Score = 40.7 bits (91), Expect = 0.022
Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCN--ILIFNRANVNCRNKKAQTPLHLAAIN 811
+S + +V + G T LH A G E I I ++ N ++T H A
Sbjct: 362 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTY 421
Query: 812 NKTV-VIRLLLD-NGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL------ 863
K++ +++ LLD N NIN +T LH A G+I + LL D+ L+
Sbjct: 422 GKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSR 481
Query: 864 ---NATEKTALAVAKDKVHLTIIDLIDNY 889
E+T L A +K H I+ L+ +Y
Sbjct: 482 SSGEKDEQTCLMWAYEKGHDAIVTLLKHY 510
Score = 33.5 bits (73), Expect = 3.4
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Query: 789 FNRANVNCRNKKAQTPLHLAAI-NNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
F++ N+N R + + LHL I K IR L+ G + + T LH A N
Sbjct: 161 FSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNA 220
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL DI + TAL +A HL D++
Sbjct: 221 ELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVL 259
>BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein.
Length = 843
Score = 87.0 bits (206), Expect = 3e-16
Identities = 47/132 (35%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G TALH+A A ++ +LL G+++ +ALH A+ GH +LL GAN
Sbjct: 201 NGFTALHLAVYKDNAELITSLLHSGADVQQVGYGGLTALHIATIAGHLEAADVLLQHGAN 260
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N ++ TPLH+A GH + ++ F ++N + E G+ PLHLAS G+
Sbjct: 261 VNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG------ADVNVSGEVGDRPLHLASAKGFL 314
Query: 611 GIARLLIEHGSE 622
IA+LL+E GS+
Sbjct: 315 NIAKLLMEEGSK 326
Score = 86.2 bits (204), Expect = 5e-16
Identities = 49/148 (33%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GLTALH+A+I G + LL+ G+ +N D + LH A+ GH+ V +LL GA++
Sbjct: 235 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 294
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + PLHLA G L+ K ++ G K ++N + + PLH S++G+
Sbjct: 295 NVSGEVGDRPLHLASAKGFLNIAKLLM----EEGSKADVNAQDNEDHVPLHFCSRFGHHD 350
Query: 612 IARLLIEHGSE--PSLQNSYHKTAFDYA 637
I + L++ E P + N Y T A
Sbjct: 351 IVKYLLQSDLEVQPHVVNIYGDTPLHLA 378
Score = 74.5 bits (175), Expect = 1e-12
Identities = 44/136 (32%), Positives = 73/136 (53%), Gaps = 7/136 (5%)
Query: 488 RDSHGLTALHVASI-HGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
R +GL+ LH+ I GK + + TL+ G + N +ALH A + + ++ LLH
Sbjct: 164 RTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLH 223
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
SGA++ Q T LH+A GHL ++ +H N+N + TPLH+A+
Sbjct: 224 SGADVQQVGYGGLTALHIATIAGHLEAADVLL---QHGA---NVNIQDAVFFTPLHIAAY 277
Query: 607 WGYEGIARLLIEHGSE 622
+G+E + RLL++ G++
Sbjct: 278 YGHEQVTRLLLKFGAD 293
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/154 (29%), Positives = 81/154 (52%), Gaps = 8/154 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ T LH+A+ +G + LL+ G+++N + LH AS++G N+ +L+
Sbjct: 264 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 323
Query: 548 G--ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
G A++N ++ + + PLH GH VK ++ S ++ + N G+TPLHLA
Sbjct: 324 GSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL----QSDLEVQPHVVNIYGDTPLHLAC 379
Query: 606 KWGYEGIARLLIEHGSEPSL--QNSYHKTAFDYA 637
G +A+ +I+ SL +N + +TAF A
Sbjct: 380 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 413
Score = 63.7 bits (148), Expect = 3e-09
Identities = 38/95 (40%), Positives = 51/95 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DV G TALH A G E ++L+ + ANVN ++ TPLH+AA V RL
Sbjct: 227 DVQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRL 286
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
LL GA++N + PLH AS G + AK+L+
Sbjct: 287 LLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 321
Score = 62.1 bits (144), Expect = 8e-09
Identities = 48/161 (29%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Query: 734 EKSNSLCHPLCECQYCKR--KTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
E SL H C C K +T + NGFTALH A E L+ +
Sbjct: 166 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 225
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A+V T LH+A I +LL +GAN+N D TPLH A+ G+ +
Sbjct: 226 ADVQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTR 285
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANK 892
+LL + D+ + L +A K L I L+ +K
Sbjct: 286 LLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSK 326
Score = 60.5 bits (140), Expect = 3e-08
Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ D+ FT LH AA YG ++ +L+ A+VN + PLHLA+ + +L
Sbjct: 260 NVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKL 319
Query: 820 LLDNG--ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
L++ G A++NA D + PLH S G+ K LL + ++
Sbjct: 320 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEV 362
Score = 42.3 bits (95), Expect = 0.007
Identities = 36/145 (24%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEI--NATDLNECSALHYASSRGHQNVLL 542
+ ++D+ LH S G IV+ LL+ E+ + ++ + LH A G V
Sbjct: 329 VNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 388
Query: 543 MLLH-SGA-NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
++ SG ++ ++NI T H A G + + + + + ININ G+T
Sbjct: 389 EIIQISGTESLTKENIFSETAFHSACTYGK--SIDLVKFLLDQN--VININHQGRDGHTG 444
Query: 601 LHLASKWGYEGIARLLIEHGSEPSL 625
LH A G+ + + L+++G++ +L
Sbjct: 445 LHSACYHGHIRLVQFLLDNGADMNL 469
Score = 40.7 bits (91), Expect = 0.022
Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCN--ILIFNRANVNCRNKKAQTPLHLAAIN 811
+S + +V + G T LH A G E I I ++ N ++T H A
Sbjct: 357 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTY 416
Query: 812 NKTV-VIRLLLD-NGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL------ 863
K++ +++ LLD N NIN +T LH A G+I + LL D+ L+
Sbjct: 417 GKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSR 476
Query: 864 ---NATEKTALAVAKDKVHLTIIDLIDNY 889
E+T L A +K H I+ L+ +Y
Sbjct: 477 SSGEKDEQTCLMWAYEKGHDAIVTLLKHY 505
Score = 33.1 bits (72), Expect = 4.5
Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Query: 789 FNRANVNCRNKKAQTPLHLAAI-NNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
F++ N+N R + + LHL I K IR L+ G + + T LH A N
Sbjct: 156 FSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNA 215
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL D+ + TAL +A HL D++
Sbjct: 216 ELITSLLHSGADVQQVGYGGLTALHIATIAGHLEAADVL 254
>AF121775-1|AAF24125.1| 366|Homo sapiens nasopharyngeal carcinoma
susceptibility protein LZ16 protein.
Length = 366
Score = 87.0 bits (206), Expect = 3e-16
Identities = 50/144 (34%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ R+ G T LH A+I G A ++ L+ G+++N D +ALH A +RG+ +V L
Sbjct: 161 LNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQL 220
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L +GA +N K +D +TPLH A NNGH VK ++ + N +N G TPL +A
Sbjct: 221 LAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGG------NPQQSNRKGETPLKVA 274
Query: 605 SKWGYEGIARLLIEHGSEPSLQNS 628
+ + LL+ G+ S + S
Sbjct: 275 NS---PTMVNLLLGKGTYTSSEES 295
Score = 58.8 bits (136), Expect = 8e-08
Identities = 43/138 (31%), Positives = 61/138 (44%)
Query: 746 CQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPL 805
CQ + S T +N + G T LH AA G LI A+VN ++ T L
Sbjct: 146 CQKGTPNSASKTKDKLNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTAL 205
Query: 806 HLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNA 865
H A V + LL GA +N + +TPLHDA+ G+ K+LL Y + N
Sbjct: 206 HEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNR 265
Query: 866 TEKTALAVAKDKVHLTII 883
+T L VA + ++
Sbjct: 266 KGETPLKVANSPTMVNLL 283
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/96 (32%), Positives = 48/96 (50%)
Query: 794 VNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
+N RN++ +T LH AAI I+ L+ GA++N D A T LH+A G AK L
Sbjct: 161 LNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQL 220
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
L+ ++ + T L A + H ++ L+ Y
Sbjct: 221 LAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRY 256
Score = 32.7 bits (71), Expect = 5.9
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 6/97 (6%)
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N++N T LH A G +K +I G +N+ + +G T LH A GY
Sbjct: 161 LNKRNERGETRLHRAAIRGDARRIKELI----SEGADVNVK--DFAGWTALHEACNRGYY 214
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+A+ L+ G+E + + T A N +V+K
Sbjct: 215 DVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVK 251
>BC069013-1|AAH69013.1| 457|Homo sapiens ANKRD11 protein protein.
Length = 457
Score = 86.6 bits (205), Expect = 3e-16
Identities = 50/144 (34%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ R+ G T LH A+I G A ++ L+ G+++N D +ALH A +RG+ +V L
Sbjct: 161 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQL 220
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L +GA +N K +D +TPLH A NNGH VK ++ + N +N G TPL +A
Sbjct: 221 LAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGG------NPQQSNRKGETPLKVA 274
Query: 605 SKWGYEGIARLLIEHGSEPSLQNS 628
+ + LL+ G+ S + S
Sbjct: 275 NS---PTMVNLLLGKGTYTSSEES 295
Score = 60.1 bits (139), Expect = 3e-08
Identities = 44/138 (31%), Positives = 61/138 (44%)
Query: 746 CQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPL 805
CQ + S T VN + G T LH AA G LI A+VN ++ T L
Sbjct: 146 CQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTAL 205
Query: 806 HLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNA 865
H A V + LL GA +N + +TPLHDA+ G+ K+LL Y + N
Sbjct: 206 HEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNR 265
Query: 866 TEKTALAVAKDKVHLTII 883
+T L VA + ++
Sbjct: 266 KGETPLKVANSPTMVNLL 283
Score = 56.0 bits (129), Expect = 6e-07
Identities = 32/96 (33%), Positives = 48/96 (50%)
Query: 794 VNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
VN RN++ +T LH AAI I+ L+ GA++N D A T LH+A G AK L
Sbjct: 161 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQL 220
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
L+ ++ + T L A + H ++ L+ Y
Sbjct: 221 LAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRY 256
Score = 33.1 bits (72), Expect = 4.5
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 6/97 (6%)
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N++N T LH A G +K +I G +N+ + +G T LH A GY
Sbjct: 161 VNKRNERGETRLHRAAIRGDARRIKELI----SEGADVNVK--DFAGWTALHEACNRGYY 214
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+A+ L+ G+E + + T A N +V+K
Sbjct: 215 DVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVK 251
>AY533563-1|AAS45544.1| 2663|Homo sapiens ankyrin repeat-containing
cofactor-1 protein.
Length = 2663
Score = 86.6 bits (205), Expect = 3e-16
Identities = 50/144 (34%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ R+ G T LH A+I G A ++ L+ G+++N D +ALH A +RG+ +V L
Sbjct: 161 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQL 220
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L +GA +N K +D +TPLH A NNGH VK ++ + N +N G TPL +A
Sbjct: 221 LAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGG------NPQQSNRKGETPLKVA 274
Query: 605 SKWGYEGIARLLIEHGSEPSLQNS 628
+ + LL+ G+ S + S
Sbjct: 275 NS---PTMVNLLLGKGTYTSSEES 295
Score = 60.1 bits (139), Expect = 3e-08
Identities = 44/138 (31%), Positives = 61/138 (44%)
Query: 746 CQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPL 805
CQ + S T VN + G T LH AA G LI A+VN ++ T L
Sbjct: 146 CQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTAL 205
Query: 806 HLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNA 865
H A V + LL GA +N + +TPLHDA+ G+ K+LL Y + N
Sbjct: 206 HEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNR 265
Query: 866 TEKTALAVAKDKVHLTII 883
+T L VA + ++
Sbjct: 266 KGETPLKVANSPTMVNLL 283
Score = 56.0 bits (129), Expect = 6e-07
Identities = 32/96 (33%), Positives = 48/96 (50%)
Query: 794 VNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
VN RN++ +T LH AAI I+ L+ GA++N D A T LH+A G AK L
Sbjct: 161 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQL 220
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
L+ ++ + T L A + H ++ L+ Y
Sbjct: 221 LAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRY 256
Score = 33.1 bits (72), Expect = 4.5
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 6/97 (6%)
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N++N T LH A G +K +I G +N+ + +G T LH A GY
Sbjct: 161 VNKRNERGETRLHRAAIRGDARRIKELI----SEGADVNVK--DFAGWTALHEACNRGYY 214
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+A+ L+ G+E + + T A N +V+K
Sbjct: 215 DVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVK 251
>AY373756-1|AAR25661.1| 2664|Homo sapiens ankyrin repeat-containing
protein protein.
Length = 2664
Score = 86.6 bits (205), Expect = 3e-16
Identities = 50/144 (34%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ R+ G T LH A+I G A ++ L+ G+++N D +ALH A +RG+ +V L
Sbjct: 162 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQL 221
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L +GA +N K +D +TPLH A NNGH VK ++ + N +N G TPL +A
Sbjct: 222 LAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGG------NPQQSNRKGETPLKVA 275
Query: 605 SKWGYEGIARLLIEHGSEPSLQNS 628
+ + LL+ G+ S + S
Sbjct: 276 NS---PTMVNLLLGKGTYTSSEES 296
Score = 60.1 bits (139), Expect = 3e-08
Identities = 44/138 (31%), Positives = 61/138 (44%)
Query: 746 CQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPL 805
CQ + S T VN + G T LH AA G LI A+VN ++ T L
Sbjct: 147 CQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTAL 206
Query: 806 HLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNA 865
H A V + LL GA +N + +TPLHDA+ G+ K+LL Y + N
Sbjct: 207 HEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNR 266
Query: 866 TEKTALAVAKDKVHLTII 883
+T L VA + ++
Sbjct: 267 KGETPLKVANSPTMVNLL 284
Score = 56.0 bits (129), Expect = 6e-07
Identities = 32/96 (33%), Positives = 48/96 (50%)
Query: 794 VNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
VN RN++ +T LH AAI I+ L+ GA++N D A T LH+A G AK L
Sbjct: 162 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQL 221
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
L+ ++ + T L A + H ++ L+ Y
Sbjct: 222 LAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRY 257
Score = 33.1 bits (72), Expect = 4.5
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 6/97 (6%)
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N++N T LH A G +K +I G +N+ + +G T LH A GY
Sbjct: 162 VNKRNERGETRLHRAAIRGDARRIKELI----SEGADVNVK--DFAGWTALHEACNRGYY 215
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+A+ L+ G+E + + T A N +V+K
Sbjct: 216 DVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVK 252
>AC017035-2|AAY15060.1| 394|Homo sapiens unknown protein.
Length = 394
Score = 86.6 bits (205), Expect = 3e-16
Identities = 106/383 (27%), Positives = 167/383 (43%), Gaps = 41/383 (10%)
Query: 527 SALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGR 586
S LH A+ GH L +LL S +++ ++ T L LA GH CV+A+I + G
Sbjct: 19 SPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALI----NQGA 74
Query: 587 KININCANESGNTPLHLASKWGYEGIARLLIEHGSEPS---LQNSYHKT----AFDYAHN 639
I + N + TPLH + G+ RLL+E P ++++ +T A Y H
Sbjct: 75 SIFVK-DNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHI 133
Query: 640 LRILQVL-KSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTND------A 692
+ +L K + + + T+ ++ E L Q +++ C D+ A
Sbjct: 134 DAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYA 193
Query: 693 SKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRK 752
+ L E + A+S D CF N Y+ + + L E Q C RK
Sbjct: 194 AARGHATWLSELLQMALSEED---CCFKDNQGYTPLHWACYNGNENCIEVLLE-QKCFRK 249
Query: 753 TESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILI--FNRANVNCRNKKAQTPLHLAAI 810
N FT LH A ++L+ + + V+CR+ K +TPLH AA
Sbjct: 250 FIG-----------NPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLHAAAF 298
Query: 811 NNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL-SYNPDITLLNATEKT 869
+ ++LLL + A +NA+D + T L A+E G GA IL+ S D+T+ + T
Sbjct: 299 ADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNT 358
Query: 870 ALAVAKDKVH----LTIIDLIDN 888
L +A K H L I+D I +
Sbjct: 359 PLHLACSKGHEKCALLILDKIQD 381
Score = 69.3 bits (162), Expect = 6e-11
Identities = 40/124 (32%), Positives = 69/124 (55%), Gaps = 4/124 (3%)
Query: 496 LHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK- 554
LH+A+ +G +E LL+ +++ D +AL A+ +GH + L++ GA+I K
Sbjct: 21 LHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINQGASIFVKD 80
Query: 555 NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIAR 614
N+ K TPLH +V NGH C++ ++ A++ ++ + G TPL LA +G+
Sbjct: 81 NVTKRTPLHASVINGHTLCLRLLLEIADNPEA---VDVKDAKGQTPLMLAVAYGHIDAVS 137
Query: 615 LLIE 618
LL+E
Sbjct: 138 LLLE 141
Score = 63.7 bits (148), Expect = 3e-09
Identities = 47/150 (31%), Positives = 76/150 (50%), Gaps = 10/150 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMG-SEINAT--DLNECSALHYASSRGHQNVLLML 544
+DS G T LH A+ G AT + LL+M SE + D + LH+A G++N + +L
Sbjct: 182 KDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVL 241
Query: 545 LHSGANINQKNIDKN-TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L +K I TPLH A+ N H +C ++ + S ++C ++ G TPLH
Sbjct: 242 LEQ--KCFRKFIGNPFTPLHCAIINDHGNCASLLLGAIDSS----IVSCRDDKGRTPLHA 295
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTA 633
A+ + +LL+ H + + ++ KTA
Sbjct: 296 AAFADHVECLQLLLRHSAPVNAVDNSGKTA 325
Score = 62.9 bits (146), Expect = 5e-09
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ G T L +A +G V LLE + ++ D+ C+ALH GH+ + MLL
Sbjct: 116 KDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQ 175
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
+I K+ TPLH A GH + ++ A + + + G TPLH A
Sbjct: 176 EVSILCKDSRGRTPLHYAAARGHATWLSELLQMAL---SEEDCCFKDNQGYTPLHWACYN 232
Query: 608 GYEGIARLLIE 618
G E +L+E
Sbjct: 233 GNENCIEVLLE 243
Score = 60.9 bits (141), Expect = 2e-08
Identities = 45/154 (29%), Positives = 72/154 (46%), Gaps = 10/154 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATD-LNECSALHYASSRGHQNVLLMLLH 546
RD G TAL +A+ G VE L+ G+ I D + + + LH + GH L +LL
Sbjct: 46 RDEKGRTALDLAAFKGHTECVEALINQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLE 105
Query: 547 SGAN---INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
N ++ K+ TPL LAV GH+ V ++ ++ N++ + G T LH
Sbjct: 106 IADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLL------EKEANVDTVDILGCTALHR 159
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
G+E ++L+E ++S +T YA
Sbjct: 160 GIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYA 193
Score = 58.4 bits (135), Expect = 1e-07
Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
++ RD G T LH A+ ++ LL + +NA D + +AL A+ G + +L
Sbjct: 282 VSCRDDKGRTPLHAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDIL 341
Query: 545 LHSG-ANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
++S A++ K+ D NTPLHLA + GH C I+
Sbjct: 342 VNSAQADLTVKDKDLNTPLHLACSKGHEKCALLIL 376
Score = 57.6 bits (133), Expect = 2e-07
Identities = 35/119 (29%), Positives = 59/119 (49%), Gaps = 9/119 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSA---LHYASSRGHQNVLLMLLHSGAN 550
T LH + I+G + LLE+ A D+ + L A + GH + + +LL AN
Sbjct: 86 TPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEAN 145
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
++ +I T LH + GH CV+ ++ ++++I C + G TPLH A+ G+
Sbjct: 146 VDTVDILGCTALHRGIMTGHEECVQMLL------EQEVSILCKDSRGRTPLHYAAARGH 198
Score = 55.2 bits (127), Expect = 1e-06
Identities = 77/359 (21%), Positives = 148/359 (41%), Gaps = 23/359 (6%)
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
LL +SG + K+ PLHLA NGH ++ ++ ++++ +E G T
Sbjct: 1 LLERTNSGFEESDSGATKS-PLHLAAYNGHHQALEVLLQSL------VDLDIRDEKGRTA 53
Query: 601 LHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHIT 660
L LA+ G+ LI G+ ++++ K +A ++ C L E I
Sbjct: 54 LDLAAFKGHTECVEALINQGASIFVKDNVTKRTPLHAS---VINGHTLCLRLLLE-IADN 109
Query: 661 SSEVKKISCESEKPTSLKLQNLTLKC-SDTNDASKTIENLKLI--ERILRAISYGDVKLA 717
V + + P L + + S + ++ + ++ + R I G +
Sbjct: 110 PEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEE-- 167
Query: 718 CFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTE----SCTDFDVNVCDSNGFTALH 773
C M ++ I + + H + +E + ++ D D+ G+T LH
Sbjct: 168 CVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLH 227
Query: 774 YAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLD--NGANINAID 831
+A Y +E C ++ + TPLH A IN+ LLL + + ++ D
Sbjct: 228 WAC-YNGNENCIEVLLEQKCFRKFIGNPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRD 286
Query: 832 VARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYA 890
TPLH A+ ++ ++LL ++ + ++ + KTAL +A + +D++ N A
Sbjct: 287 DKGRTPLHAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSA 345
Score = 50.0 bits (114), Expect = 4e-05
Identities = 39/136 (28%), Positives = 60/136 (44%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLLEM--GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
T LH A I+ LL S ++ D + LH A+ H L +LL A +
Sbjct: 256 TPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLHAAAFADHVECLQLLLRHSAPV 315
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + T L +A NG V ++ A+ ++ ++ NTPLHLA G+E
Sbjct: 316 NAVDNSGKTALMMAAENGQAGAVDILVNSAQ-----ADLTVKDKDLNTPLHLACSKGHEK 370
Query: 612 IARLLIEHGSEPSLQN 627
A L+++ + SL N
Sbjct: 371 CALLILDKIQDESLIN 386
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/105 (31%), Positives = 53/105 (50%), Gaps = 1/105 (0%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
V+ D G T LH AA E +L+ + A VN + +T L +AA N + + +L
Sbjct: 282 VSCRDDKGRTPLHAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDIL 341
Query: 821 LDNG-ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLN 864
+++ A++ D NTPLH A G+ A ++L D +L+N
Sbjct: 342 VNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQDESLIN 386
Score = 37.5 bits (83), Expect = 0.21
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFN-RANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN D++G TAL AA G +IL+ + +A++ ++K TPLHLA L
Sbjct: 315 VNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALL 374
Query: 820 LLDNGANINAIDVARN 835
+LD + + I+ N
Sbjct: 375 ILDKIQDESLINEKNN 390
>AB209186-1|BAD92423.1| 439|Homo sapiens ankyrin repeat domain 11
variant protein.
Length = 439
Score = 86.6 bits (205), Expect = 3e-16
Identities = 50/144 (34%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ R+ G T LH A+I G A ++ L+ G+++N D +ALH A +RG+ +V L
Sbjct: 175 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQL 234
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L +GA +N K +D +TPLH A NNGH VK ++ + N +N G TPL +A
Sbjct: 235 LAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGG------NPQQSNRKGETPLKVA 288
Query: 605 SKWGYEGIARLLIEHGSEPSLQNS 628
+ + LL+ G+ S + S
Sbjct: 289 NS---PTMVNLLLGKGTYTSSEES 309
Score = 60.1 bits (139), Expect = 3e-08
Identities = 44/138 (31%), Positives = 61/138 (44%)
Query: 746 CQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPL 805
CQ + S T VN + G T LH AA G LI A+VN ++ T L
Sbjct: 160 CQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTAL 219
Query: 806 HLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNA 865
H A V + LL GA +N + +TPLHDA+ G+ K+LL Y + N
Sbjct: 220 HEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNR 279
Query: 866 TEKTALAVAKDKVHLTII 883
+T L VA + ++
Sbjct: 280 KGETPLKVANSPTMVNLL 297
Score = 56.0 bits (129), Expect = 6e-07
Identities = 32/96 (33%), Positives = 48/96 (50%)
Query: 794 VNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
VN RN++ +T LH AAI I+ L+ GA++N D A T LH+A G AK L
Sbjct: 175 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQL 234
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
L+ ++ + T L A + H ++ L+ Y
Sbjct: 235 LAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRY 270
Score = 33.1 bits (72), Expect = 4.5
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 6/97 (6%)
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N++N T LH A G +K +I G +N+ + +G T LH A GY
Sbjct: 175 VNKRNERGETRLHRAAIRGDARRIKELI----SEGADVNVK--DFAGWTALHEACNRGYY 228
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+A+ L+ G+E + + T A N +V+K
Sbjct: 229 DVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVK 265
>BC098394-1|AAH98394.1| 1327|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase
protein.
Length = 1327
Score = 86.2 bits (204), Expect = 5e-16
Identities = 108/387 (27%), Positives = 165/387 (42%), Gaps = 42/387 (10%)
Query: 527 SALHYASSRGH---QNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
+ALH A + H + V +LL GAN+N+KN D TPLH+A H + V +++ +H
Sbjct: 524 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAH-NDVMEVLH--KH 580
Query: 584 SGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRIL 643
+ +N + G T LH A+ G+ RLL+ +GS+PS+ + TA N +
Sbjct: 581 GAK---MNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMG-NEAVQ 636
Query: 644 QVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIE 703
Q+L TP I +S+V E+ K L+ + CS N + +E +
Sbjct: 637 QILSESTP-------IRTSDVDYRLLEASKAGD--LETVKQLCSSQNVNCRDLEG-RHST 686
Query: 704 RILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV 763
+ A Y V + + ++ A DK L + Y + VNV
Sbjct: 687 PLHFAAGYNRVSVVEYLLHHGADVH-AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 745
Query: 764 CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTV--VIR--- 818
D FT LH AA G E C +L+ + A+ +N+ TPL L + + ++R
Sbjct: 746 ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDA 805
Query: 819 LLLD--------------NGANINAIDV-ARN-TPLHDASETGNIGAAKILLSYNPDITL 862
LLD NIN D RN TPLH A+ N+ A+ LL + D+
Sbjct: 806 ALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNA 865
Query: 863 LNATEKTALAVAKDKVHLTIIDLIDNY 889
+ L A H+ I L+ Y
Sbjct: 866 QDKGGLIPLHNAASYGHVDIAALLIKY 892
Score = 78.6 bits (185), Expect = 9e-14
Identities = 102/405 (25%), Positives = 168/405 (41%), Gaps = 37/405 (9%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+RD GL LH A G A +V LL G++ NA D + LH A+ +G +V ++LL
Sbjct: 244 ARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQ 303
Query: 547 SGANINQKNIDKNTPLHLAVNNGHL----HCVKAIIYFAEHSGRK---------ININCA 593
GA+ N +N D + L LA + K + A SG + +N+NC
Sbjct: 304 HGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCH 363
Query: 594 NESG--NTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH----KTAFDYAHNLRILQVLK 647
G +TPLHLA+ + I +LL++HG++ ++ A Y H +LK
Sbjct: 364 ASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLK 423
Query: 648 --SCTPNL----FEYIHITSSEVKKISC-----ESEKPTSLKLQNLT-LKCSDTNDASKT 695
+C + F +H +S+ + C PT + + + + T + +
Sbjct: 424 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRER 483
Query: 696 IENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTES 755
+ +L+A D+ + ++ F P ++ C K+ TE
Sbjct: 484 LTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTEL 543
Query: 756 CTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
NV + N T LH AA ++ +L + A +N + QT LH AA+
Sbjct: 544 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGH 603
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
RLLL G++ + I + T A++ GN +IL P
Sbjct: 604 LQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQILSESTP 644
Score = 76.2 bits (179), Expect = 5e-13
Identities = 84/320 (26%), Positives = 146/320 (45%), Gaps = 42/320 (13%)
Query: 504 KATIVETLLEMGSE--INATDLN--ECSALHYASSRGHQNVLLMLLHSGANINQKNIDKN 559
KA +ET+ ++ S +N DL + LH+A+ +V+ LLH GA+++ K+
Sbjct: 659 KAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGL 718
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
PLH A + GH + ++ H ++N A+ TPLH A+ G I +LL++H
Sbjct: 719 VPLHNACSYGHYEVAELLV---RHGA---SVNVADLWKFTPLHEAAAKGKYEICKLLLKH 772
Query: 620 GSEPSLQNSYHKTAFDYAH--NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G++P+ +N T D + I +L+ L + V+K+ C E
Sbjct: 773 GADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKL-CTPE----- 826
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI-APDK--- 733
+ C DT + T +L A Y ++++A + +++ A + A DK
Sbjct: 827 -----NINCRDTQGRNSTPLHL--------AAGYNNLEVAEYL--LEHGADVNAQDKGGL 871
Query: 734 -EKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRA 792
N+ + + K +C VN D FT LH AA+ G + C +L+ + A
Sbjct: 872 IPLHNAASYGHVDIAALLIKYNTC----VNATDKWAFTPLHEAAQKGRTQLCALLLAHGA 927
Query: 793 NVNCRNKKAQTPLHLAAINN 812
+ +N++ QTPL LA ++
Sbjct: 928 DPTMKNQEGQTPLDLATADD 947
Score = 73.7 bits (173), Expect = 3e-12
Identities = 53/157 (33%), Positives = 82/157 (52%), Gaps = 17/157 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
++D GL LH A +G + E L+ G+ +N DL + + LH A+++G + +LL
Sbjct: 712 AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLK 771
Query: 547 SGANINQKNIDKNTPLHLAVNNG-----HLHCVKAIIYFAEHSG-----RKI----NINC 592
GA+ +KN D NTPL L V G L A + A G +K+ NINC
Sbjct: 772 HGADPTKKNRDGNTPLDL-VKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINC 830
Query: 593 ANESG--NTPLHLASKWGYEGIARLLIEHGSEPSLQN 627
+ G +TPLHLA+ + +A L+EHG++ + Q+
Sbjct: 831 RDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQD 867
Score = 72.1 bits (169), Expect = 8e-12
Identities = 43/120 (35%), Positives = 66/120 (55%), Gaps = 2/120 (1%)
Query: 757 TDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
T +VN S+G T LH AA Y +L+ + A+V+ ++K PLH A
Sbjct: 356 TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHY 415
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V LLL +GA +NA+D+ + TPLH+A+ + +LLS+ D TL+N K+A+ +A
Sbjct: 416 EVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 475
Score = 68.9 bits (161), Expect = 7e-11
Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 3/137 (2%)
Query: 751 RKTESCTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
R + CT ++N D+ G T LH AA Y E L+ + A+VN ++K PLH A
Sbjct: 818 RVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNA 877
Query: 809 AINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK 868
A + LL+ +NA D TPLH+A++ G +LL++ D T+ N +
Sbjct: 878 ASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQ 937
Query: 869 TALAVA-KDKVHLTIID 884
T L +A D + +ID
Sbjct: 938 TPLDLATADDIRALLID 954
Score = 66.1 bits (154), Expect = 5e-10
Identities = 89/320 (27%), Positives = 143/320 (44%), Gaps = 36/320 (11%)
Query: 490 SHGLTALHVASIHGKATIVETLLEMGSEINATDL--NECSALHYASSRGHQNVLLMLLHS 547
S L L A +G + V+ L++ + +NA D+ + S LH+A+ G ++V+ LL
Sbjct: 180 SGALRELLEACRNGDVSRVKRLVD-AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQM 238
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GAN++ ++ PLH A + GH V ++ + N N TPLH A+
Sbjct: 239 GANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWN------YTPLHEAAIK 292
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKI 667
G + +L++HG++P+++N+ K+A D A + VL EY E +
Sbjct: 293 GKIDVCIVLLQHGADPNIRNTDGKSALDLA-DPSAKAVLTG------EYKKDELLEAAR- 344
Query: 668 SCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA 727
S EK +L L L + C ++ T +L A Y V++ + + + A
Sbjct: 345 SGNEEKLMAL-LTPLNVNCHASDGRKSTPLHL--------AAGYNRVRIV--QLLLQHGA 393
Query: 728 FI-APDKEKSNSLCHPLCECQYCKRKTESCTDFD--VNVCDSNGFTALHYAARYGLDEFC 784
+ A DK L H C + + TE VN D FT LH AA E C
Sbjct: 394 DVHAKDKGGLVPL-HNACSYGHYE-VTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVC 451
Query: 785 NILIFNRAN---VNCRNKKA 801
++L+ + A+ VNC K A
Sbjct: 452 SLLLSHGADPTLVNCHGKSA 471
Score = 65.3 bits (152), Expect = 9e-10
Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 6/113 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH A+ + + ++VE LL G++++A D LH A S GH V +L+ GA++N
Sbjct: 686 TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 745
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
++ K TPLH A G K ++ +K N GNTPL L +
Sbjct: 746 ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKK------NRDGNTPLDLVKE 792
Score = 63.7 bits (148), Expect = 3e-09
Identities = 42/117 (35%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 760 DVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+VN D G + LH+AA +G + L+ ANV+ R+ PLH A V+
Sbjct: 206 NVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVV 265
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LLL GA+ NA D TPLH+A+ G I +LL + D + N K+AL +A
Sbjct: 266 SLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
Score = 60.5 bits (140), Expect = 3e-08
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCR--NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDV 832
AAR G +E L+ NVNC + + TPLHLAA N+ +++LLL +GA+++A D
Sbjct: 342 AARSGNEEKLMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDK 400
Query: 833 ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
PLH+A G+ ++LL + + ++ + T L A K + + L+
Sbjct: 401 GGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 454
Score = 57.6 bits (133), Expect = 2e-07
Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 13/141 (9%)
Query: 481 TCPTMTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQ 538
T + RD+ G T LH+A+ + + E LLE G+++NA D LH A+S GH
Sbjct: 824 TPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHV 883
Query: 539 NVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESG 597
++ +L+ +N + TPLH A G C + + A+ + + N+ G
Sbjct: 884 DIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMK-------NQEG 936
Query: 598 NTPLHLASKWGYEGIARLLIE 618
TPL LA+ + I LLI+
Sbjct: 937 QTPLDLATA---DDIRALLID 954
Score = 40.3 bits (90), Expect = 0.030
Identities = 38/140 (27%), Positives = 61/140 (43%), Gaps = 16/140 (11%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
M + D+ G TALH A++ G LL GS+ + L + A+ G++ V +
Sbjct: 584 MNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAV-QQI 638
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESG--NTPLH 602
L I ++D L A G L VK + N+NC + G +TPLH
Sbjct: 639 LSESTPIRTSDVDYR--LLEASKAGDLETVKQLC-------SSQNVNCRDLEGRHSTPLH 689
Query: 603 LASKWGYEGIARLLIEHGSE 622
A+ + + L+ HG++
Sbjct: 690 FAAGYNRVSVVEYLLHHGAD 709
Score = 38.7 bits (86), Expect = 0.091
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 802 QTPLHLAAIN---NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
+T LH A + + V LLL GAN+N + TPLH A+E + ++L +
Sbjct: 523 ETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGA 582
Query: 859 DITLLNATEKTALAVAKDKVHLTIIDLIDNYAN 891
+ L+ +TAL A HL L+ +Y +
Sbjct: 583 KMNALDTLGQTALHRAALAGHLQTCRLLLSYGS 615
>AB209339-1|BAD92576.1| 1055|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase
variant protein.
Length = 1055
Score = 86.2 bits (204), Expect = 5e-16
Identities = 108/387 (27%), Positives = 165/387 (42%), Gaps = 42/387 (10%)
Query: 527 SALHYASSRGH---QNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
+ALH A + H + V +LL GAN+N+KN D TPLH+A H + V +++ +H
Sbjct: 252 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAH-NDVMEVLH--KH 308
Query: 584 SGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRIL 643
+ +N + G T LH A+ G+ RLL+ +GS+PS+ + TA N +
Sbjct: 309 GAK---MNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMG-NEAVQ 364
Query: 644 QVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIE 703
Q+L TP I +S+V E+ K L+ + CS N + +E +
Sbjct: 365 QILSESTP-------IRTSDVDYRLLEASKAGD--LETVKQLCSSQNVNCRDLEG-RHST 414
Query: 704 RILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV 763
+ A Y V + + ++ A DK L + Y + VNV
Sbjct: 415 PLHFAAGYNRVSVVEYLLHHGADVH-AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 473
Query: 764 CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTV--VIR--- 818
D FT LH AA G E C +L+ + A+ +N+ TPL L + + ++R
Sbjct: 474 ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDA 533
Query: 819 LLLD--------------NGANINAIDV-ARN-TPLHDASETGNIGAAKILLSYNPDITL 862
LLD NIN D RN TPLH A+ N+ A+ LL + D+
Sbjct: 534 ALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNA 593
Query: 863 LNATEKTALAVAKDKVHLTIIDLIDNY 889
+ L A H+ I L+ Y
Sbjct: 594 QDKGGLIPLHNAASYGHVDIAALLIKY 620
Score = 76.2 bits (179), Expect = 5e-13
Identities = 84/320 (26%), Positives = 146/320 (45%), Gaps = 42/320 (13%)
Query: 504 KATIVETLLEMGSE--INATDLN--ECSALHYASSRGHQNVLLMLLHSGANINQKNIDKN 559
KA +ET+ ++ S +N DL + LH+A+ +V+ LLH GA+++ K+
Sbjct: 387 KAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGL 446
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
PLH A + GH + ++ H ++N A+ TPLH A+ G I +LL++H
Sbjct: 447 VPLHNACSYGHYEVAELLV---RHGA---SVNVADLWKFTPLHEAAAKGKYEICKLLLKH 500
Query: 620 GSEPSLQNSYHKTAFDYAH--NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G++P+ +N T D + I +L+ L + V+K+ C E
Sbjct: 501 GADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKL-CTPE----- 554
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI-APDK--- 733
+ C DT + T +L A Y ++++A + +++ A + A DK
Sbjct: 555 -----NINCRDTQGRNSTPLHL--------AAGYNNLEVAEYL--LEHGADVNAQDKGGL 599
Query: 734 -EKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRA 792
N+ + + K +C VN D FT LH AA+ G + C +L+ + A
Sbjct: 600 IPLHNAASYGHVDIAALLIKYNTC----VNATDKWAFTPLHEAAQKGRTQLCALLLAHGA 655
Query: 793 NVNCRNKKAQTPLHLAAINN 812
+ +N++ QTPL LA ++
Sbjct: 656 DPTMKNQEGQTPLDLATADD 675
Score = 73.7 bits (173), Expect = 3e-12
Identities = 53/157 (33%), Positives = 82/157 (52%), Gaps = 17/157 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
++D GL LH A +G + E L+ G+ +N DL + + LH A+++G + +LL
Sbjct: 440 AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLK 499
Query: 547 SGANINQKNIDKNTPLHLAVNNG-----HLHCVKAIIYFAEHSG-----RKI----NINC 592
GA+ +KN D NTPL L V G L A + A G +K+ NINC
Sbjct: 500 HGADPTKKNRDGNTPLDL-VKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINC 558
Query: 593 ANESG--NTPLHLASKWGYEGIARLLIEHGSEPSLQN 627
+ G +TPLHLA+ + +A L+EHG++ + Q+
Sbjct: 559 RDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQD 595
Score = 72.1 bits (169), Expect = 8e-12
Identities = 43/120 (35%), Positives = 66/120 (55%), Gaps = 2/120 (1%)
Query: 757 TDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
T +VN S+G T LH AA Y +L+ + A+V+ ++K PLH A
Sbjct: 84 TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHY 143
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V LLL +GA +NA+D+ + TPLH+A+ + +LLS+ D TL+N K+A+ +A
Sbjct: 144 EVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 203
Score = 68.9 bits (161), Expect = 7e-11
Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 3/137 (2%)
Query: 751 RKTESCTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
R + CT ++N D+ G T LH AA Y E L+ + A+VN ++K PLH A
Sbjct: 546 RVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNA 605
Query: 809 AINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK 868
A + LL+ +NA D TPLH+A++ G +LL++ D T+ N +
Sbjct: 606 ASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQ 665
Query: 869 TALAVA-KDKVHLTIID 884
T L +A D + +ID
Sbjct: 666 TPLDLATADDIRALLID 682
Score = 65.3 bits (152), Expect = 9e-10
Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 6/113 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH A+ + + ++VE LL G++++A D LH A S GH V +L+ GA++N
Sbjct: 414 TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 473
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
++ K TPLH A G K ++ +K N GNTPL L +
Sbjct: 474 ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKK------NRDGNTPLDLVKE 520
Score = 60.5 bits (140), Expect = 3e-08
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCR--NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDV 832
AAR G +E L+ NVNC + + TPLHLAA N+ +++LLL +GA+++A D
Sbjct: 70 AARSGNEEKLMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDK 128
Query: 833 ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
PLH+A G+ ++LL + + ++ + T L A K + + L+
Sbjct: 129 GGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 182
Score = 58.8 bits (136), Expect = 8e-08
Identities = 33/108 (30%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D T LH+A+ + + IV+ LL+ G++++A D LH A S GH V +LL G
Sbjct: 94 DGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG 153
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANES 596
A +N ++ + TPLH A + + ++ H +NC +S
Sbjct: 154 ACVNAMDLWQFTPLHEAASKNRVEVCSLLL---SHGADPTLVNCHGKS 198
Score = 58.0 bits (134), Expect = 1e-07
Identities = 89/373 (23%), Positives = 151/373 (40%), Gaps = 37/373 (9%)
Query: 519 NATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHL----HCV 574
NA D + LH A+ +G +V ++LL GA+ N +N D + L LA +
Sbjct: 4 NARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYK 63
Query: 575 KAIIYFAEHSGRK---------ININCANESG--NTPLHLASKWGYEGIARLLIEHGSEP 623
K + A SG + +N+NC G +TPLHLA+ + I +LL++HG++
Sbjct: 64 KDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADV 123
Query: 624 SLQNSYH----KTAFDYAHNLRILQVLK--SCTPNL----FEYIHITSSEVKKISC---- 669
++ A Y H +LK +C + F +H +S+ + C
Sbjct: 124 HAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLL 183
Query: 670 -ESEKPTSLKLQNLT-LKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA 727
PT + + + + T + + + +L+A D+ + ++
Sbjct: 184 SHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIIN 243
Query: 728 FIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNG--FTALHYAARYGLDEFCN 785
F P ++ C K+ TE NV + N T LH AA ++
Sbjct: 244 FKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVME 303
Query: 786 ILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETG 845
+L + A +N + QT LH AA+ RLLL G++ + I + T A++ G
Sbjct: 304 VLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMG 359
Query: 846 NIGAAKILLSYNP 858
N +IL P
Sbjct: 360 NEAVQQILSESTP 372
Score = 57.6 bits (133), Expect = 2e-07
Identities = 37/142 (26%), Positives = 68/142 (47%), Gaps = 6/142 (4%)
Query: 496 LHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKN 555
L A + ++ L + +A+D + + LH A+ ++ +LL GA+++ K+
Sbjct: 68 LEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKD 127
Query: 556 IDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARL 615
PLH A + GH + ++ +H +N + TPLH A+ + L
Sbjct: 128 KGGLVPLHNACSYGHYEVTELLL---KHGA---CVNAMDLWQFTPLHEAASKNRVEVCSL 181
Query: 616 LIEHGSEPSLQNSYHKTAFDYA 637
L+ HG++P+L N + K+A D A
Sbjct: 182 LLSHGADPTLVNCHGKSAVDMA 203
Score = 57.6 bits (133), Expect = 2e-07
Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 13/141 (9%)
Query: 481 TCPTMTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQ 538
T + RD+ G T LH+A+ + + E LLE G+++NA D LH A+S GH
Sbjct: 552 TPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHV 611
Query: 539 NVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESG 597
++ +L+ +N + TPLH A G C + + A+ + + N+ G
Sbjct: 612 DIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMK-------NQEG 664
Query: 598 NTPLHLASKWGYEGIARLLIE 618
TPL LA+ + I LLI+
Sbjct: 665 QTPLDLATA---DDIRALLID 682
Score = 52.4 bits (120), Expect = 7e-06
Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 3/90 (3%)
Query: 494 TALH--VASIHGKAT-IVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
TALH VAS+H K + E LL G+ +N + + + LH A+ R H +V+ +L GA
Sbjct: 252 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK 311
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
+N + T LH A GHL + ++ +
Sbjct: 312 MNALDTLGQTALHRAALAGHLQTCRLLLSY 341
Score = 46.4 bits (105), Expect = 5e-04
Identities = 26/79 (32%), Positives = 42/79 (53%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
++D GL LH A +G + E LL+ G+ +NA DL + + LH A+S+ V +LL
Sbjct: 125 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 184
Query: 547 SGANINQKNIDKNTPLHLA 565
GA+ N + + +A
Sbjct: 185 HGADPTLVNCHGKSAVDMA 203
Score = 44.4 bits (100), Expect = 0.002
Identities = 39/151 (25%), Positives = 71/151 (47%), Gaps = 21/151 (13%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T LHVA+ ++E L + G+++NA D +ALH A+ GH +LL G++ +
Sbjct: 287 MTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPS 346
Query: 553 -----------------QKNIDKNTPLHLA-VNNGHLHCVKA-IIYFAEHSGRKININCA 593
Q+ + ++TP+ + V+ L KA + + N+NC
Sbjct: 347 IISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCR 406
Query: 594 NESG--NTPLHLASKWGYEGIARLLIEHGSE 622
+ G +TPLH A+ + + L+ HG++
Sbjct: 407 DLEGRHSTPLHFAAGYNRVSVVEYLLHHGAD 437
Score = 38.7 bits (86), Expect = 0.091
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 802 QTPLHLAAIN---NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
+T LH A + + V LLL GAN+N + TPLH A+E + ++L +
Sbjct: 251 ETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGA 310
Query: 859 DITLLNATEKTALAVAKDKVHLTIIDLIDNYAN 891
+ L+ +TAL A HL L+ +Y +
Sbjct: 311 KMNALDTLGQTALHRAALAGHLQTCRLLLSYGS 343
Score = 34.3 bits (75), Expect = 1.9
Identities = 19/50 (38%), Positives = 27/50 (54%)
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
A+ NA D TPLH+A+ G I +LL + D + N K+AL +A
Sbjct: 1 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 50
Score = 32.3 bits (70), Expect = 7.9
Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 4/74 (5%)
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A+ N R+ TPLH AAI K V +LL +GA+ N RNT A + + A
Sbjct: 1 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPN----IRNTDGKSALDLADPSAKA 56
Query: 852 ILLSYNPDITLLNA 865
+L LL A
Sbjct: 57 VLTGEYKKDELLEA 70
>AK025859-1|BAB15260.1| 460|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22206 fis, clone HRC01431. ).
Length = 460
Score = 85.8 bits (203), Expect = 6e-16
Identities = 87/339 (25%), Positives = 150/339 (44%), Gaps = 16/339 (4%)
Query: 521 TDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
T+ N +AL A + GH+ ++ LL GA+I ++ TPL LA GH+ V+ ++
Sbjct: 43 TESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILL-- 100
Query: 581 AEHSGRKININCANE-SGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
G +I +E + +TPL LA G + + LL+ G+ +N T A +
Sbjct: 101 ----GNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAAS 156
Query: 640 LRILQVLKSCTPNLFEYIHITSSE--VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIE 697
+ ++K E T S+ + + + + ++ L SD N +T
Sbjct: 157 GGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNR 216
Query: 698 NLKLIERILRAISYGDVKLACFYMNIDYSAF--IAPDKEKSNSLCHPLCECQYCKRKTES 755
N L + + L N+++ A + P E ++ + + +
Sbjct: 217 NTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASG-----GYAEVGRVLLDK 271
Query: 756 CTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTV 815
D + S+ TAL AA G +FC +LI A+++ RNKK TPL LAA
Sbjct: 272 GADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLD 331
Query: 816 VIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
V++LL+ GA+++A D + TPL A G++ + L+
Sbjct: 332 VVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLV 370
Score = 79.0 bits (186), Expect = 7e-14
Identities = 47/140 (33%), Positives = 80/140 (57%), Gaps = 5/140 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLH 546
RD G T L +A+ G +VE LL G++I A ++ + + L A S G Q V+ +LL
Sbjct: 76 RDKKGFTPLILAATAGHVGVVEILLGNGADIEAQSERTKDTPLSLACSGGRQEVVELLLA 135
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GAN +N+ TPL LA + G+++ +K ++ ++G +IN ++ G +PL LA+
Sbjct: 136 RGANKEHRNVSDYTPLSLAASGGYVNIIKILL----NAGAEINSRTGSKLGISPLMLAAM 191
Query: 607 WGYEGIARLLIEHGSEPSLQ 626
G+ +LL++ GS+ + Q
Sbjct: 192 NGHTAAVKLLLDMGSDINAQ 211
Score = 69.3 bits (162), Expect = 6e-11
Identities = 48/135 (35%), Positives = 71/135 (52%), Gaps = 7/135 (5%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+S+ TAL +A G +V+TLLE G+ I D + L A++ GH V+ +LL +G
Sbjct: 44 ESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLGNG 103
Query: 549 ANIN-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A+I Q K+TPL LA + G V+ ++ R N N S TPL LA+
Sbjct: 104 ADIEAQSERTKDTPLSLACSGGRQEVVELLL------ARGANKEHRNVSDYTPLSLAASG 157
Query: 608 GYEGIARLLIEHGSE 622
GY I ++L+ G+E
Sbjct: 158 GYVNIIKILLNAGAE 172
Score = 65.7 bits (153), Expect = 7e-10
Identities = 55/201 (27%), Positives = 97/201 (48%), Gaps = 18/201 (8%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDL--NECSALHYASSRGHQNVLLMLL 545
R GLT L A+ G A + LL+ G+++NA + + +AL A+ +GH +L+
Sbjct: 245 RAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLI 304
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+I+ +N NTPL LA N GHL V+ ++ +G +++ A+ TPL A
Sbjct: 305 GRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLV----QAG--ADVDAADNRKITPLMAAF 358
Query: 606 KWGYEGIARLLIEHGSE-PSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
+ G+ + R L++ ++ PS Y + ++LK C + + +
Sbjct: 359 RKGHVKVVRYLVKEVNQFPS-----DSECMRYIATITDKEMLKKCHLCMESIVQAKDRQ- 412
Query: 665 KKISCESEKPTSLKLQNLTLK 685
+ E+ K S+ L+ L L+
Sbjct: 413 ---AAEANKNASILLEELDLE 430
Score = 62.9 bits (146), Expect = 5e-09
Identities = 43/130 (33%), Positives = 68/130 (52%), Gaps = 3/130 (2%)
Query: 760 DVNV-CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
D+N ++N TAL A G E ++L+ +ANV R K TPL AA V R
Sbjct: 207 DINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGR 266
Query: 819 LLLDNGANINA--IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD GA++NA + +R+T L A++ G+ ++L+ I + N T L +A +
Sbjct: 267 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAAN 326
Query: 877 KVHLTIIDLI 886
HL ++ L+
Sbjct: 327 GGHLDVVQLL 336
Score = 62.5 bits (145), Expect = 6e-09
Identities = 39/131 (29%), Positives = 69/131 (52%), Gaps = 8/131 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL +A G+ +V LL+ + + + L A+S G+ V +LL GA++N
Sbjct: 218 TALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 277
Query: 554 KNI--DKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ ++T L +A + GH + +I GR +I+ N+ GNTPL LA+ G+
Sbjct: 278 PPVPSSRDTALTIAADKGHYKFCELLI------GRGAHIDVRNKKGNTPLWLAANGGHLD 331
Query: 612 IARLLIEHGSE 622
+ +LL++ G++
Sbjct: 332 VVQLLVQAGAD 342
Score = 60.1 bits (139), Expect = 3e-08
Identities = 46/159 (28%), Positives = 78/159 (49%), Gaps = 8/159 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLHSGAN 550
G++ L +A+++G V+ LL+MGS+INA + N +AL A +G V+ +LL AN
Sbjct: 182 GISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKAN 241
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ + TPL A + G+ + ++ G +N S +T L +A+ G+
Sbjct: 242 VEHRAKTGLTPLMEAASGGYAEVGRVLL----DKGADVNAPPVPSSRDTALTIAADKGHY 297
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHN---LRILQVL 646
LLI G+ ++N T A N L ++Q+L
Sbjct: 298 KFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLL 336
Score = 59.7 bits (138), Expect = 5e-08
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D D +SN TAL A G +E L+ A++ R+KK TPL LAA V+
Sbjct: 38 DIDAQT-ESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVV 96
Query: 818 RLLLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LL NGA+I A + ++TPL A G ++LL+ + N ++ T L++A
Sbjct: 97 EILLGNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAAS 156
Query: 877 KVHLTIIDLIDN 888
++ II ++ N
Sbjct: 157 GGYVNIIKILLN 168
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/127 (31%), Positives = 64/127 (50%), Gaps = 7/127 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L +A G+ +VE LL G+ ++++ + L A+S G+ N++ +LL++GA IN
Sbjct: 116 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS 175
Query: 554 KNIDK--NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ K +PL LA NGH VK ++ +I N NT L LA G
Sbjct: 176 RTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETN-----RNTALTLACFQGRTE 230
Query: 612 IARLLIE 618
+ LL++
Sbjct: 231 VVSLLLD 237
Score = 53.2 bits (122), Expect = 4e-06
Identities = 41/126 (32%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L A G E +L+ AN RN TPL LAA +I++LL+ GA IN+
Sbjct: 116 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS 175
Query: 830 IDVAR--NTPLHDASETGNIGAAKILLSYNPDITL-LNATEKTALAVAKDKVHLTIID-L 885
++ +PL A+ G+ A K+LL DI + TAL +A + ++ L
Sbjct: 176 RTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLL 235
Query: 886 IDNYAN 891
+D AN
Sbjct: 236 LDRKAN 241
Score = 52.8 bits (121), Expect = 5e-06
Identities = 79/346 (22%), Positives = 140/346 (40%), Gaps = 16/346 (4%)
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
Q + +T L LA GH V+ ++ R +I ++ G TPL LA+ G+ G+
Sbjct: 42 QTESNHDTALTLACAGGHEELVQTLLE------RGASIEHRDKKGFTPLILAATAGHVGV 95
Query: 613 ARLLIEHGSEPSLQNSYHK-TAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCES 671
+L+ +G++ Q+ K T A + +V++ H S+ +S +
Sbjct: 96 VEILLGNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAA 155
Query: 672 EKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAP 731
++ L ++ N S+T L + +L A++ G A + +D + I
Sbjct: 156 SGGYVNIIKILLNAGAEIN--SRTGSKLGISPLMLAAMN-GHT--AAVKLLLDMGSDINA 210
Query: 732 DKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCD--SNGFTALHYAARYGLDEFCNILIF 789
E + + L Q D NV G T L AA G E +L+
Sbjct: 211 QIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLD 270
Query: 790 NRANVNCRN--KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
A+VN T L +AA LL+ GA+I+ + NTPL A+ G++
Sbjct: 271 KGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHL 330
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKY 893
++L+ D+ + + T L A K H+ ++ + N++
Sbjct: 331 DVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQF 376
Score = 48.4 bits (110), Expect = 1e-04
Identities = 29/96 (30%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +SRD TAL +A+ G E L+ G+ I+ + + L A++ GH +V+
Sbjct: 279 PVPSSRD----TALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQ 334
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+L+ +GA+++ + K TPL A GH+ V+ ++
Sbjct: 335 LLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLV 370
>AF082557-1|AAC79842.1| 1094|Homo sapiens TRF1-interacting
ankyrin-related ADP-ribose polymerase protein.
Length = 1094
Score = 85.8 bits (203), Expect = 6e-16
Identities = 108/387 (27%), Positives = 163/387 (42%), Gaps = 42/387 (10%)
Query: 527 SALHYASSRGH---QNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
+ALH A + H + V +LL GAN+N+KN D TPLH+A H + V +++ +H
Sbjct: 291 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAH-NDVMEVLH--KH 347
Query: 584 SGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRIL 643
+ +N + G T LH A+ G+ RLL+ +GS+PS+ + TA N +
Sbjct: 348 GAK---MNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMG-NEAVQ 403
Query: 644 QVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIE 703
Q+L TP I +S+V E+ K L+ + CS N + +E +
Sbjct: 404 QILSESTP-------IRTSDVDYRLLEASKAGD--LETVKQLCSSQNVNCRDLEG-RHST 453
Query: 704 RILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV 763
+ A Y V + + ++ A DK L + Y + VNV
Sbjct: 454 PLHFAAGYNRVSVVEYLLHHGADVH-AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 512
Query: 764 CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL---- 819
D FT LH AA G E C +L+ + A+ +N+ TPL L + + L
Sbjct: 513 ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLKGDA 572
Query: 820 -LLD--------------NGANINAIDV-ARN-TPLHDASETGNIGAAKILLSYNPDITL 862
LLD NIN D RN TPLH A+ N+ A+ LL + D+
Sbjct: 573 ALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNA 632
Query: 863 LNATEKTALAVAKDKVHLTIIDLIDNY 889
+ L A H+ I L+ Y
Sbjct: 633 QDKGGLIPLHNAASYGHVDIAALLIKY 659
Score = 78.6 bits (185), Expect = 9e-14
Identities = 102/405 (25%), Positives = 168/405 (41%), Gaps = 37/405 (9%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+RD GL LH A G A +V LL G++ NA D + LH A+ +G +V ++LL
Sbjct: 11 ARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQ 70
Query: 547 SGANINQKNIDKNTPLHLAVNNGHL----HCVKAIIYFAEHSGRK---------ININCA 593
GA+ N +N D + L LA + K + A SG + +N+NC
Sbjct: 71 HGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCH 130
Query: 594 NESG--NTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH----KTAFDYAHNLRILQVLK 647
G +TPLHLA+ + I +LL++HG++ ++ A Y H +LK
Sbjct: 131 ASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLK 190
Query: 648 --SCTPNL----FEYIHITSSEVKKISC-----ESEKPTSLKLQNLT-LKCSDTNDASKT 695
+C + F +H +S+ + C PT + + + + T + +
Sbjct: 191 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRER 250
Query: 696 IENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTES 755
+ +L+A D+ + ++ F P ++ C K+ TE
Sbjct: 251 LTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTEL 310
Query: 756 CTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
NV + N T LH AA ++ +L + A +N + QT LH AA+
Sbjct: 311 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGH 370
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
RLLL G++ + I + T A++ GN +IL P
Sbjct: 371 LQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQILSESTP 411
Score = 77.4 bits (182), Expect = 2e-13
Identities = 85/320 (26%), Positives = 146/320 (45%), Gaps = 42/320 (13%)
Query: 504 KATIVETLLEMGSE--INATDLN--ECSALHYASSRGHQNVLLMLLHSGANINQKNIDKN 559
KA +ET+ ++ S +N DL + LH+A+ +V+ LLH GA+++ K+
Sbjct: 426 KAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGL 485
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
PLH A + GH + ++ H ++N A+ TPLH A+ G I +LL++H
Sbjct: 486 VPLHNACSYGHYEVAELLV---RHGA---SVNVADLWKFTPLHEAAAKGKYEICKLLLKH 539
Query: 620 GSEPSLQNSYHKTAFDYAH--NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G++P+ +N T D + I +LK L + V+K+ C E
Sbjct: 540 GADPTKKNRDGNTPLDLVKEGDTDIQDLLKGDAALLDAAKKGCLARVQKL-CTPE----- 593
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI-APDK--- 733
+ C DT + T +L A Y ++++A + +++ A + A DK
Sbjct: 594 -----NINCRDTQGRNSTPLHL--------AAGYNNLEVAEYL--LEHGADVNAQDKGGL 638
Query: 734 -EKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRA 792
N+ + + K +C VN D FT LH AA+ G + C +L+ + A
Sbjct: 639 IPLHNAASYGHVDIAALLIKYNTC----VNATDKWAFTPLHEAAQKGRTQLCALLLAHGA 694
Query: 793 NVNCRNKKAQTPLHLAAINN 812
+ +N++ QTPL LA ++
Sbjct: 695 DPTMKNQEGQTPLDLATADD 714
Score = 73.7 bits (173), Expect = 3e-12
Identities = 53/157 (33%), Positives = 82/157 (52%), Gaps = 17/157 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
++D GL LH A +G + E L+ G+ +N DL + + LH A+++G + +LL
Sbjct: 479 AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLK 538
Query: 547 SGANINQKNIDKNTPLHLAVNNG-----HLHCVKAIIYFAEHSG-----RKI----NINC 592
GA+ +KN D NTPL L V G L A + A G +K+ NINC
Sbjct: 539 HGADPTKKNRDGNTPLDL-VKEGDTDIQDLLKGDAALLDAAKKGCLARVQKLCTPENINC 597
Query: 593 ANESG--NTPLHLASKWGYEGIARLLIEHGSEPSLQN 627
+ G +TPLHLA+ + +A L+EHG++ + Q+
Sbjct: 598 RDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQD 634
Score = 72.1 bits (169), Expect = 8e-12
Identities = 43/120 (35%), Positives = 66/120 (55%), Gaps = 2/120 (1%)
Query: 757 TDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
T +VN S+G T LH AA Y +L+ + A+V+ ++K PLH A
Sbjct: 123 TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHY 182
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V LLL +GA +NA+D+ + TPLH+A+ + +LLS+ D TL+N K+A+ +A
Sbjct: 183 EVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 242
Score = 68.9 bits (161), Expect = 7e-11
Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 3/137 (2%)
Query: 751 RKTESCTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
R + CT ++N D+ G T LH AA Y E L+ + A+VN ++K PLH A
Sbjct: 585 RVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNA 644
Query: 809 AINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK 868
A + LL+ +NA D TPLH+A++ G +LL++ D T+ N +
Sbjct: 645 ASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQ 704
Query: 869 TALAVA-KDKVHLTIID 884
T L +A D + +ID
Sbjct: 705 TPLDLATADDIRALLID 721
Score = 65.3 bits (152), Expect = 9e-10
Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 6/113 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH A+ + + ++VE LL G++++A D LH A S GH V +L+ GA++N
Sbjct: 453 TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 512
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
++ K TPLH A G K ++ +K N GNTPL L +
Sbjct: 513 ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKK------NRDGNTPLDLVKE 559
Score = 60.5 bits (140), Expect = 3e-08
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCR--NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDV 832
AAR G +E L+ NVNC + + TPLHLAA N+ +++LLL +GA+++A D
Sbjct: 109 AARSGNEEKLMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDK 167
Query: 833 ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
PLH+A G+ ++LL + + ++ + T L A K + + L+
Sbjct: 168 GGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 221
Score = 57.6 bits (133), Expect = 2e-07
Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 13/141 (9%)
Query: 481 TCPTMTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQ 538
T + RD+ G T LH+A+ + + E LLE G+++NA D LH A+S GH
Sbjct: 591 TPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHV 650
Query: 539 NVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESG 597
++ +L+ +N + TPLH A G C + + A+ + + N+ G
Sbjct: 651 DIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMK-------NQEG 703
Query: 598 NTPLHLASKWGYEGIARLLIE 618
TPL LA+ + I LLI+
Sbjct: 704 QTPLDLATA---DDIRALLID 721
Score = 53.6 bits (123), Expect = 3e-06
Identities = 32/83 (38%), Positives = 43/83 (51%)
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
ANV+ R+ PLH A V+ LLL GA+ NA D TPLH+A+ G I
Sbjct: 7 ANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCI 66
Query: 852 ILLSYNPDITLLNATEKTALAVA 874
+LL + D + N K+AL +A
Sbjct: 67 VLLQHGADPNIRNTDGKSALDLA 89
Score = 48.8 bits (111), Expect = 8e-05
Identities = 73/264 (27%), Positives = 113/264 (42%), Gaps = 33/264 (12%)
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GAN++ ++ PLH A + GH V ++ + N N TPLH
Sbjct: 2 LLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNY------TPLHE 55
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
A+ G + +L++HG++P+++N+ K+A D A + VL EY E
Sbjct: 56 AAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA-DPSAKAVLTG------EYKKDELLE 108
Query: 664 VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNI 723
+ S EK +L L L + C ++ T +L A Y V++ + +
Sbjct: 109 AAR-SGNEEKLMAL-LTPLNVNCHASDGRKSTPLHL--------AAGYNRVRIV--QLLL 156
Query: 724 DYSAFI-APDKEKSNSLCHPLCECQYCKRKTESCTDFD--VNVCDSNGFTALHYAARYGL 780
+ A + A DK L H C + + TE VN D FT LH AA
Sbjct: 157 QHGADVHAKDKGGLVPL-HNACSYGHYE-VTELLLKHGACVNAMDLWQFTPLHEAASKNR 214
Query: 781 DEFCNILIFNRAN---VNCRNKKA 801
E C++L+ + A+ VNC K A
Sbjct: 215 VEVCSLLLSHGADPTLVNCHGKSA 238
Score = 47.6 bits (108), Expect = 2e-04
Identities = 35/106 (33%), Positives = 49/106 (46%), Gaps = 4/106 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ D G LH A +G E ++L+ A+ N R+ TPLH AAI K V +
Sbjct: 8 NVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIV 67
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNA 865
LL +GA+ N RNT A + + A +L LL A
Sbjct: 68 LLQHGADPN----IRNTDGKSALDLADPSAKAVLTGEYKKDELLEA 109
Score = 45.6 bits (103), Expect = 8e-04
Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
LL+MG+ ++A D LH A S GH V+ +LL GA+ N ++ TPLH A G
Sbjct: 2 LLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGK 61
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ I +H + N N G + L LA
Sbjct: 62 ---IDVCIVLLQHGA---DPNIRNTDGKSALDLA 89
Score = 40.3 bits (90), Expect = 0.030
Identities = 38/140 (27%), Positives = 61/140 (43%), Gaps = 16/140 (11%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
M + D+ G TALH A++ G LL GS+ + L + A+ G++ V +
Sbjct: 351 MNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAV-QQI 405
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESG--NTPLH 602
L I ++D L A G L VK + N+NC + G +TPLH
Sbjct: 406 LSESTPIRTSDVDYR--LLEASKAGDLETVKQLC-------SSQNVNCRDLEGRHSTPLH 456
Query: 603 LASKWGYEGIARLLIEHGSE 622
A+ + + L+ HG++
Sbjct: 457 FAAGYNRVSVVEYLLHHGAD 476
Score = 38.7 bits (86), Expect = 0.091
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 802 QTPLHLAAIN---NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
+T LH A + + V LLL GAN+N + TPLH A+E + ++L +
Sbjct: 290 ETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGA 349
Query: 859 DITLLNATEKTALAVAKDKVHLTIIDLIDNYAN 891
+ L+ +TAL A HL L+ +Y +
Sbjct: 350 KMNALDTLGQTALHRAALAGHLQTCRLLLSYGS 382
>AF082556-1|AAC79841.1| 1327|Homo sapiens TRF1-interacting
ankyrin-related ADP-ribose polymerase protein.
Length = 1327
Score = 85.8 bits (203), Expect = 6e-16
Identities = 108/387 (27%), Positives = 163/387 (42%), Gaps = 42/387 (10%)
Query: 527 SALHYASSRGH---QNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
+ALH A + H + V +LL GAN+N+KN D TPLH+A H + V +++ +H
Sbjct: 524 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAH-NDVMEVLH--KH 580
Query: 584 SGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRIL 643
+ +N + G T LH A+ G+ RLL+ +GS+PS+ + TA N +
Sbjct: 581 GAK---MNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMG-NEAVQ 636
Query: 644 QVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIE 703
Q+L TP I +S+V E+ K L+ + CS N + +E +
Sbjct: 637 QILSESTP-------IRTSDVDYRLLEASKAGD--LETVKQLCSSQNVNCRDLEG-RHST 686
Query: 704 RILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNV 763
+ A Y V + + ++ A DK L + Y + VNV
Sbjct: 687 PLHFAAGYNRVSVVEYLLHHGADVH-AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 745
Query: 764 CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL---- 819
D FT LH AA G E C +L+ + A+ +N+ TPL L + + L
Sbjct: 746 ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLKGDA 805
Query: 820 -LLD--------------NGANINAIDV-ARN-TPLHDASETGNIGAAKILLSYNPDITL 862
LLD NIN D RN TPLH A+ N+ A+ LL + D+
Sbjct: 806 ALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNA 865
Query: 863 LNATEKTALAVAKDKVHLTIIDLIDNY 889
+ L A H+ I L+ Y
Sbjct: 866 QDKGGLIPLHNAASYGHVDIAALLIKY 892
Score = 78.6 bits (185), Expect = 9e-14
Identities = 102/405 (25%), Positives = 168/405 (41%), Gaps = 37/405 (9%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+RD GL LH A G A +V LL G++ NA D + LH A+ +G +V ++LL
Sbjct: 244 ARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQ 303
Query: 547 SGANINQKNIDKNTPLHLAVNNGHL----HCVKAIIYFAEHSGRK---------ININCA 593
GA+ N +N D + L LA + K + A SG + +N+NC
Sbjct: 304 HGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCH 363
Query: 594 NESG--NTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH----KTAFDYAHNLRILQVLK 647
G +TPLHLA+ + I +LL++HG++ ++ A Y H +LK
Sbjct: 364 ASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLK 423
Query: 648 --SCTPNL----FEYIHITSSEVKKISC-----ESEKPTSLKLQNLT-LKCSDTNDASKT 695
+C + F +H +S+ + C PT + + + + T + +
Sbjct: 424 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRER 483
Query: 696 IENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTES 755
+ +L+A D+ + ++ F P ++ C K+ TE
Sbjct: 484 LTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTEL 543
Query: 756 CTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
NV + N T LH AA ++ +L + A +N + QT LH AA+
Sbjct: 544 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGH 603
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
RLLL G++ + I + T A++ GN +IL P
Sbjct: 604 LQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQILSESTP 644
Score = 77.4 bits (182), Expect = 2e-13
Identities = 85/320 (26%), Positives = 146/320 (45%), Gaps = 42/320 (13%)
Query: 504 KATIVETLLEMGSE--INATDLN--ECSALHYASSRGHQNVLLMLLHSGANINQKNIDKN 559
KA +ET+ ++ S +N DL + LH+A+ +V+ LLH GA+++ K+
Sbjct: 659 KAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGL 718
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
PLH A + GH + ++ H ++N A+ TPLH A+ G I +LL++H
Sbjct: 719 VPLHNACSYGHYEVAELLV---RHGA---SVNVADLWKFTPLHEAAAKGKYEICKLLLKH 772
Query: 620 GSEPSLQNSYHKTAFDYAH--NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G++P+ +N T D + I +LK L + V+K+ C E
Sbjct: 773 GADPTKKNRDGNTPLDLVKEGDTDIQDLLKGDAALLDAAKKGCLARVQKL-CTPE----- 826
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI-APDK--- 733
+ C DT + T +L A Y ++++A + +++ A + A DK
Sbjct: 827 -----NINCRDTQGRNSTPLHL--------AAGYNNLEVAEYL--LEHGADVNAQDKGGL 871
Query: 734 -EKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRA 792
N+ + + K +C VN D FT LH AA+ G + C +L+ + A
Sbjct: 872 IPLHNAASYGHVDIAALLIKYNTC----VNATDKWAFTPLHEAAQKGRTQLCALLLAHGA 927
Query: 793 NVNCRNKKAQTPLHLAAINN 812
+ +N++ QTPL LA ++
Sbjct: 928 DPTMKNQEGQTPLDLATADD 947
Score = 73.7 bits (173), Expect = 3e-12
Identities = 53/157 (33%), Positives = 82/157 (52%), Gaps = 17/157 (10%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
++D GL LH A +G + E L+ G+ +N DL + + LH A+++G + +LL
Sbjct: 712 AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLK 771
Query: 547 SGANINQKNIDKNTPLHLAVNNG-----HLHCVKAIIYFAEHSG-----RKI----NINC 592
GA+ +KN D NTPL L V G L A + A G +K+ NINC
Sbjct: 772 HGADPTKKNRDGNTPLDL-VKEGDTDIQDLLKGDAALLDAAKKGCLARVQKLCTPENINC 830
Query: 593 ANESG--NTPLHLASKWGYEGIARLLIEHGSEPSLQN 627
+ G +TPLHLA+ + +A L+EHG++ + Q+
Sbjct: 831 RDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQD 867
Score = 72.1 bits (169), Expect = 8e-12
Identities = 43/120 (35%), Positives = 66/120 (55%), Gaps = 2/120 (1%)
Query: 757 TDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
T +VN S+G T LH AA Y +L+ + A+V+ ++K PLH A
Sbjct: 356 TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHY 415
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V LLL +GA +NA+D+ + TPLH+A+ + +LLS+ D TL+N K+A+ +A
Sbjct: 416 EVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 475
Score = 68.9 bits (161), Expect = 7e-11
Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 3/137 (2%)
Query: 751 RKTESCTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
R + CT ++N D+ G T LH AA Y E L+ + A+VN ++K PLH A
Sbjct: 818 RVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNA 877
Query: 809 AINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK 868
A + LL+ +NA D TPLH+A++ G +LL++ D T+ N +
Sbjct: 878 ASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQ 937
Query: 869 TALAVA-KDKVHLTIID 884
T L +A D + +ID
Sbjct: 938 TPLDLATADDIRALLID 954
Score = 66.1 bits (154), Expect = 5e-10
Identities = 89/320 (27%), Positives = 143/320 (44%), Gaps = 36/320 (11%)
Query: 490 SHGLTALHVASIHGKATIVETLLEMGSEINATDL--NECSALHYASSRGHQNVLLMLLHS 547
S L L A +G + V+ L++ + +NA D+ + S LH+A+ G ++V+ LL
Sbjct: 180 SGALRELLEACRNGDVSRVKRLVD-AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQM 238
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GAN++ ++ PLH A + GH V ++ + N N TPLH A+
Sbjct: 239 GANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWN------YTPLHEAAIK 292
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKI 667
G + +L++HG++P+++N+ K+A D A + VL EY E +
Sbjct: 293 GKIDVCIVLLQHGADPNIRNTDGKSALDLA-DPSAKAVLTG------EYKKDELLEAAR- 344
Query: 668 SCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSA 727
S EK +L L L + C ++ T +L A Y V++ + + + A
Sbjct: 345 SGNEEKLMAL-LTPLNVNCHASDGRKSTPLHL--------AAGYNRVRIV--QLLLQHGA 393
Query: 728 FI-APDKEKSNSLCHPLCECQYCKRKTESCTDFD--VNVCDSNGFTALHYAARYGLDEFC 784
+ A DK L H C + + TE VN D FT LH AA E C
Sbjct: 394 DVHAKDKGGLVPL-HNACSYGHYE-VTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVC 451
Query: 785 NILIFNRAN---VNCRNKKA 801
++L+ + A+ VNC K A
Sbjct: 452 SLLLSHGADPTLVNCHGKSA 471
Score = 65.3 bits (152), Expect = 9e-10
Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 6/113 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH A+ + + ++VE LL G++++A D LH A S GH V +L+ GA++N
Sbjct: 686 TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 745
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
++ K TPLH A G K ++ +K N GNTPL L +
Sbjct: 746 ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKK------NRDGNTPLDLVKE 792
Score = 63.7 bits (148), Expect = 3e-09
Identities = 42/117 (35%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 760 DVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+VN D G + LH+AA +G + L+ ANV+ R+ PLH A V+
Sbjct: 206 NVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVV 265
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LLL GA+ NA D TPLH+A+ G I +LL + D + N K+AL +A
Sbjct: 266 SLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
Score = 60.5 bits (140), Expect = 3e-08
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCR--NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDV 832
AAR G +E L+ NVNC + + TPLHLAA N+ +++LLL +GA+++A D
Sbjct: 342 AARSGNEEKLMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDK 400
Query: 833 ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
PLH+A G+ ++LL + + ++ + T L A K + + L+
Sbjct: 401 GGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 454
Score = 57.6 bits (133), Expect = 2e-07
Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 13/141 (9%)
Query: 481 TCPTMTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQ 538
T + RD+ G T LH+A+ + + E LLE G+++NA D LH A+S GH
Sbjct: 824 TPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHV 883
Query: 539 NVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESG 597
++ +L+ +N + TPLH A G C + + A+ + + N+ G
Sbjct: 884 DIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMK-------NQEG 936
Query: 598 NTPLHLASKWGYEGIARLLIE 618
TPL LA+ + I LLI+
Sbjct: 937 QTPLDLATA---DDIRALLID 954
Score = 40.3 bits (90), Expect = 0.030
Identities = 38/140 (27%), Positives = 61/140 (43%), Gaps = 16/140 (11%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
M + D+ G TALH A++ G LL GS+ + L + A+ G++ V +
Sbjct: 584 MNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAV-QQI 638
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESG--NTPLH 602
L I ++D L A G L VK + N+NC + G +TPLH
Sbjct: 639 LSESTPIRTSDVDYR--LLEASKAGDLETVKQLC-------SSQNVNCRDLEGRHSTPLH 689
Query: 603 LASKWGYEGIARLLIEHGSE 622
A+ + + L+ HG++
Sbjct: 690 FAAGYNRVSVVEYLLHHGAD 709
Score = 38.7 bits (86), Expect = 0.091
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 802 QTPLHLAAIN---NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
+T LH A + + V LLL GAN+N + TPLH A+E + ++L +
Sbjct: 523 ETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGA 582
Query: 859 DITLLNATEKTALAVAKDKVHLTIIDLIDNYAN 891
+ L+ +TAL A HL L+ +Y +
Sbjct: 583 KMNALDTLGQTALHRAALAGHLQTCRLLLSYGS 615
>BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein.
Length = 1500
Score = 85.4 bits (202), Expect = 8e-16
Identities = 86/338 (25%), Positives = 149/338 (44%), Gaps = 14/338 (4%)
Query: 521 TDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
T+ N +AL A + GH+ ++ LL GA+I ++ TPL LA GH+ V+ ++
Sbjct: 1079 TESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILL-- 1136
Query: 581 AEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNL 640
+G I + + +TPL LA G + + LL+ G+ +N T A +
Sbjct: 1137 --DNGADIEAQ-SERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASG 1193
Query: 641 RILQVLKSCTPNLFEYIHITSSE--VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN 698
+ ++K E T S+ + + + + ++ L SD N +T N
Sbjct: 1194 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRN 1253
Query: 699 LKLIERILRAISYGDVKLACFYMNIDYSAF--IAPDKEKSNSLCHPLCECQYCKRKTESC 756
L + + L N+++ A + P E ++ + + +
Sbjct: 1254 TALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASG-----GYAEVGRVLLDKG 1308
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
D + S+ TAL AA G +FC +LI A+++ RNKK TPL LAA V
Sbjct: 1309 ADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDV 1368
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
++LL+ GA+++A D + TPL A G++ + L+
Sbjct: 1369 VQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLV 1406
Score = 81.0 bits (191), Expect = 2e-14
Identities = 93/398 (23%), Positives = 164/398 (41%), Gaps = 20/398 (5%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L A+ G IV+ LL +++NA +AL YA + G+ +V+ +LL SGA+I
Sbjct: 302 ITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIE 361
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +G IN + +NE + L LA G+ +
Sbjct: 362 DHNENGHTPLMEAGSAGHVEVARLLL----ENGAGINTH-SNEFKESALTLACYKGHLEM 416
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPNLFEYIHITSSEVKKISC 669
R L+E G++ + TA A ++ + ++L + S + +C
Sbjct: 417 VRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 476
Query: 670 ESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI 729
+ L + ND T ++ A G ++ + A I
Sbjct: 477 GGHVELAALLIERGASLEEVNDEGYT--------PLMEAAREGHEEMVALLLG--QGANI 526
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
E++ L C + ++ + T L AA+ G E L+
Sbjct: 527 NAQTEETQETALTLACCGGFLEVADFLIKAGADI-ELGCSTPLMEAAQEGHLELVKYLLA 585
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
ANV+ T L A N T V +LL GA++ TPL A+ G++
Sbjct: 586 AGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCT 645
Query: 850 AKILLSYNPDITLLNA-TEKTALAVAKDKVHLTIIDLI 886
+ L+S ++ A + T L++A HL +++L+
Sbjct: 646 VQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELL 683
Score = 80.6 bits (190), Expect = 2e-14
Identities = 47/140 (33%), Positives = 81/140 (57%), Gaps = 5/140 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLH 546
RD G T L +A+ G +VE LL+ G++I A ++ + + L A S G Q V+ +LL
Sbjct: 1112 RDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLA 1171
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GAN +N+ TPL LA + G+++ +K ++ ++G +IN ++ G +PL LA+
Sbjct: 1172 RGANKEHRNVSDYTPLSLAASGGYVNIIKILL----NAGAEINSRTGSKLGISPLMLAAM 1227
Query: 607 WGYEGIARLLIEHGSEPSLQ 626
G+ +LL++ GS+ + Q
Sbjct: 1228 NGHTAAVKLLLDMGSDINAQ 1247
Score = 69.7 bits (163), Expect = 4e-11
Identities = 48/135 (35%), Positives = 71/135 (52%), Gaps = 7/135 (5%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+S+ TAL +A G +V+TLLE G+ I D + L A++ GH V+ +LL +G
Sbjct: 1080 ESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNG 1139
Query: 549 ANIN-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A+I Q K+TPL LA + G V+ ++ R N N S TPL LA+
Sbjct: 1140 ADIEAQSERTKDTPLSLACSGGRQEVVELLL------ARGANKEHRNVSDYTPLSLAASG 1193
Query: 608 GYEGIARLLIEHGSE 622
GY I ++L+ G+E
Sbjct: 1194 GYVNIIKILLNAGAE 1208
Score = 68.5 bits (160), Expect = 1e-10
Identities = 43/131 (32%), Positives = 69/131 (52%), Gaps = 5/131 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A+ G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++
Sbjct: 566 TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 625
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A GH+ V+ +I G +N AN + +T L LA G+ +
Sbjct: 626 ESEGGRTPLMKAARAGHVCTVQFLI----SKGANVNRTTAN-NDHTVLSLACAGGHLAVV 680
Query: 614 RLLIEHGSEPS 624
LL+ HG++P+
Sbjct: 681 ELLLAHGADPT 691
Score = 65.7 bits (153), Expect = 7e-10
Identities = 55/201 (27%), Positives = 97/201 (48%), Gaps = 18/201 (8%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDL--NECSALHYASSRGHQNVLLMLL 545
R GLT L A+ G A + LL+ G+++NA + + +AL A+ +GH +L+
Sbjct: 1281 RAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLI 1340
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+I+ +N NTPL LA N GHL V+ ++ +G +++ A+ TPL A
Sbjct: 1341 GRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLV----QAG--ADVDAADNRKITPLMAAF 1394
Query: 606 KWGYEGIARLLIEHGSE-PSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
+ G+ + R L++ ++ PS Y + ++LK C + + +
Sbjct: 1395 RKGHVKVVRYLVKEVNQFPS-----DSECMRYIATITDKEMLKKCHLCMESIVQAKDRQ- 1448
Query: 665 KKISCESEKPTSLKLQNLTLK 685
+ E+ K S+ L+ L L+
Sbjct: 1449 ---AAEANKNASILLEELDLE 1466
Score = 62.9 bits (146), Expect = 5e-09
Identities = 43/130 (33%), Positives = 68/130 (52%), Gaps = 3/130 (2%)
Query: 760 DVNV-CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
D+N ++N TAL A G E ++L+ +ANV R K TPL AA V R
Sbjct: 1243 DINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGR 1302
Query: 819 LLLDNGANINA--IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD GA++NA + +R+T L A++ G+ ++L+ I + N T L +A +
Sbjct: 1303 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAAN 1362
Query: 877 KVHLTIIDLI 886
HL ++ L+
Sbjct: 1363 GGHLDVVQLL 1372
Score = 62.5 bits (145), Expect = 6e-09
Identities = 44/132 (33%), Positives = 68/132 (51%), Gaps = 2/132 (1%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D D +SN TAL A G +E L+ A++ R+KK TPL LAA V+
Sbjct: 1074 DIDAQT-ESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVV 1132
Query: 818 RLLLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLDNGA+I A + ++TPL A G ++LL+ + N ++ T L++A
Sbjct: 1133 EILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAAS 1192
Query: 877 KVHLTIIDLIDN 888
++ II ++ N
Sbjct: 1193 GGYVNIIKILLN 1204
Score = 62.5 bits (145), Expect = 6e-09
Identities = 39/131 (29%), Positives = 69/131 (52%), Gaps = 8/131 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL +A G+ +V LL+ + + + L A+S G+ V +LL GA++N
Sbjct: 1254 TALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 1313
Query: 554 KNI--DKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ ++T L +A + GH + +I GR +I+ N+ GNTPL LA+ G+
Sbjct: 1314 PPVPSSRDTALTIAADKGHYKFCELLI------GRGAHIDVRNKKGNTPLWLAANGGHLD 1367
Query: 612 IARLLIEHGSE 622
+ +LL++ G++
Sbjct: 1368 VVQLLVQAGAD 1378
Score = 60.1 bits (139), Expect = 3e-08
Identities = 46/159 (28%), Positives = 78/159 (49%), Gaps = 8/159 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLHSGAN 550
G++ L +A+++G V+ LL+MGS+INA + N +AL A +G V+ +LL AN
Sbjct: 1218 GISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKAN 1277
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ + TPL A + G+ + ++ G +N S +T L +A+ G+
Sbjct: 1278 VEHRAKTGLTPLMEAASGGYAEVGRVLL----DKGADVNAPPVPSSRDTALTIAADKGHY 1333
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHN---LRILQVL 646
LLI G+ ++N T A N L ++Q+L
Sbjct: 1334 KFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLL 1372
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/142 (31%), Positives = 69/142 (48%), Gaps = 7/142 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++ S G TAL A G +V+ LLE G+ I + N + L A S GH V +L
Sbjct: 327 VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLL 386
Query: 545 LHSGANIN-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L +GA IN N K + L LA GHL V+ ++ K + +T L
Sbjct: 387 LENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHK------TDEMHTALME 440
Query: 604 ASKWGYEGIARLLIEHGSEPSL 625
A G+ +ARLL++ G++ ++
Sbjct: 441 ACMDGHVEVARLLLDSGAQVNM 462
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/127 (31%), Positives = 64/127 (50%), Gaps = 7/127 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L +A G+ +VE LL G+ ++++ + L A+S G+ N++ +LL++GA IN
Sbjct: 1152 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS 1211
Query: 554 KNIDK--NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ K +PL LA NGH VK ++ +I N NT L LA G
Sbjct: 1212 RTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETN-----RNTALTLACFQGRTE 1266
Query: 612 IARLLIE 618
+ LL++
Sbjct: 1267 VVSLLLD 1273
Score = 55.6 bits (128), Expect = 7e-07
Identities = 98/404 (24%), Positives = 161/404 (39%), Gaps = 34/404 (8%)
Query: 504 KATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLH 563
+A T + S NA + S L A S G N + LL G ++N+ + + L
Sbjct: 214 EAAAALTRMRAESTANAGQSDNRS-LAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLC 272
Query: 564 LAVNNGHLHCVKAIIYFAEHSGRKININCANESGN-TPLHLASKWGYEGIARLLIEHGSE 622
LA + G+ + ++ A H+ N+ G+ TPL A+ G+ I +LL+ H ++
Sbjct: 273 LACSAGYYELAQVLL--AMHA----NVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKAD 326
Query: 623 PSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNL 682
+ Q+S TA YA C + + + I +E + ++
Sbjct: 327 VNAQSSTGNTALTYA-----------CAGGYVDVVKVLLESGASIEDHNENGHTPLME-- 373
Query: 683 TLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI----APDKEKSNS 738
A +EN I + LAC+ +++ F+ A + K++
Sbjct: 374 AGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDE 433
Query: 739 LCHPLCE-CQYCKRKTESC---TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANV 794
+ L E C + + VN+ + + L AA G E +LI A++
Sbjct: 434 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASL 493
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA-IDVARNTPLHDASETGNIGAAKIL 853
N + TPL AA ++ LLL GANINA + + T L A G + A L
Sbjct: 494 EEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFL 553
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANKYANT 896
+ DI L T L A + HL ++ L+ AN +A T
Sbjct: 554 IKAGADIEL---GCSTPLMEAAQEGHLELVKYLLAAGANVHATT 594
Score = 54.4 bits (125), Expect = 2e-06
Identities = 79/346 (22%), Positives = 141/346 (40%), Gaps = 16/346 (4%)
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
Q + +T L LA GH V+ ++ R +I ++ G TPL LA+ G+ G+
Sbjct: 1078 QTESNHDTALTLACAGGHEELVQTLLE------RGASIEHRDKKGFTPLILAATAGHVGV 1131
Query: 613 ARLLIEHGSEPSLQNSYHK-TAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCES 671
+L+++G++ Q+ K T A + +V++ H S+ +S +
Sbjct: 1132 VEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAA 1191
Query: 672 EKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAP 731
++ L ++ N S+T L + +L A++ G A + +D + I
Sbjct: 1192 SGGYVNIIKILLNAGAEIN--SRTGSKLGISPLMLAAMN-GHT--AAVKLLLDMGSDINA 1246
Query: 732 DKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCD--SNGFTALHYAARYGLDEFCNILIF 789
E + + L Q D NV G T L AA G E +L+
Sbjct: 1247 QIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLD 1306
Query: 790 NRANVNCRN--KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
A+VN T L +AA LL+ GA+I+ + NTPL A+ G++
Sbjct: 1307 KGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHL 1366
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKY 893
++L+ D+ + + T L A K H+ ++ + N++
Sbjct: 1367 DVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQF 1412
Score = 50.0 bits (114), Expect = 4e-05
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ + G TAL YA G + ++L+ A++ ++ +TPL AA ++
Sbjct: 589 NVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQF 648
Query: 820 LLDNGANINAIDVAR-NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
L+ GAN+N +T L A G++ ++LL++ D T T L A
Sbjct: 649 LISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGG 708
Query: 879 HLTIIDLIDNYAN 891
H +++ + +Y N
Sbjct: 709 HTSVVCYLLDYPN 721
Score = 48.4 bits (110), Expect = 1e-04
Identities = 29/96 (30%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +SRD TAL +A+ G E L+ G+ I+ + + L A++ GH +V+
Sbjct: 1315 PVPSSRD----TALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQ 1370
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+L+ +GA+++ + K TPL A GH+ V+ ++
Sbjct: 1371 LLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLV 1406
Score = 46.0 bits (104), Expect = 6e-04
Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 7/129 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G TAL A +G + + LL+ G+++ + L A+ GH + L+ GAN+
Sbjct: 597 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANV 656
Query: 552 NQKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N+ + +T L LA GHL V+ ++ ++ + G+T L A+K G+
Sbjct: 657 NRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRL------KDGSTMLIEAAKGGHT 710
Query: 611 GIARLLIEH 619
+ L+++
Sbjct: 711 SVVCYLLDY 719
>AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein.
Length = 2486
Score = 85.4 bits (202), Expect = 8e-16
Identities = 86/338 (25%), Positives = 149/338 (44%), Gaps = 14/338 (4%)
Query: 521 TDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
T+ N +AL A + GH+ ++ LL GA+I ++ TPL LA GH+ V+ ++
Sbjct: 962 TESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILL-- 1019
Query: 581 AEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNL 640
+G I + + +TPL LA G + + LL+ G+ +N T A +
Sbjct: 1020 --DNGADIEAQ-SERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASG 1076
Query: 641 RILQVLKSCTPNLFEYIHITSSE--VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN 698
+ ++K E T S+ + + + + ++ L SD N +T N
Sbjct: 1077 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRN 1136
Query: 699 LKLIERILRAISYGDVKLACFYMNIDYSAF--IAPDKEKSNSLCHPLCECQYCKRKTESC 756
L + + L N+++ A + P E ++ + + +
Sbjct: 1137 TALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASG-----GYAEVGRVLLDKG 1191
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
D + S+ TAL AA G +FC +LI A+++ RNKK TPL LAA V
Sbjct: 1192 ADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDV 1251
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
++LL+ GA+++A D + TPL A G++ + L+
Sbjct: 1252 VQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLV 1289
Score = 81.8 bits (193), Expect = 1e-14
Identities = 93/398 (23%), Positives = 165/398 (41%), Gaps = 20/398 (5%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T+L A+ G IV+ LL +++NA +AL YA + G+ +V+ +LL SGA+I
Sbjct: 186 ITSLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIE 245
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +G IN + +NE + L LA G+ +
Sbjct: 246 DHNENGHTPLMEAGSAGHVEVARLLL----ENGAGINTH-SNEFKESALTLACYKGHLEM 300
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPNLFEYIHITSSEVKKISC 669
R L+E G++ + TA A ++ + ++L + S + +C
Sbjct: 301 VRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 360
Query: 670 ESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI 729
+ L + ND T ++ A G ++ + A I
Sbjct: 361 GGHVELAALLIERGASLEEVNDEGYT--------PLMEAAREGHEEMVALLLG--QGANI 410
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
E++ L C + ++ + T L AA+ G E L+
Sbjct: 411 NAQTEETQETALTLACCGGFLEVADFLIKAGADI-ELGCSTPLMEAAQEGHLELVKYLLA 469
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
ANV+ T L A N T V +LL GA++ TPL A+ G++
Sbjct: 470 AGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCT 529
Query: 850 AKILLSYNPDITLLNA-TEKTALAVAKDKVHLTIIDLI 886
+ L+S ++ A + T L++A HL +++L+
Sbjct: 530 VQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELL 567
Score = 80.6 bits (190), Expect = 2e-14
Identities = 47/140 (33%), Positives = 81/140 (57%), Gaps = 5/140 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLH 546
RD G T L +A+ G +VE LL+ G++I A ++ + + L A S G Q V+ +LL
Sbjct: 995 RDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLA 1054
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GAN +N+ TPL LA + G+++ +K ++ ++G +IN ++ G +PL LA+
Sbjct: 1055 RGANKEHRNVSDYTPLSLAASGGYVNIIKILL----NAGAEINSRTGSKLGISPLMLAAM 1110
Query: 607 WGYEGIARLLIEHGSEPSLQ 626
G+ +LL++ GS+ + Q
Sbjct: 1111 NGHTAAVKLLLDMGSDINAQ 1130
Score = 69.7 bits (163), Expect = 4e-11
Identities = 48/135 (35%), Positives = 71/135 (52%), Gaps = 7/135 (5%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+S+ TAL +A G +V+TLLE G+ I D + L A++ GH V+ +LL +G
Sbjct: 963 ESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNG 1022
Query: 549 ANIN-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A+I Q K+TPL LA + G V+ ++ R N N S TPL LA+
Sbjct: 1023 ADIEAQSERTKDTPLSLACSGGRQEVVELLL------ARGANKEHRNVSDYTPLSLAASG 1076
Query: 608 GYEGIARLLIEHGSE 622
GY I ++L+ G+E
Sbjct: 1077 GYVNIIKILLNAGAE 1091
Score = 68.5 bits (160), Expect = 1e-10
Identities = 43/131 (32%), Positives = 69/131 (52%), Gaps = 5/131 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A+ G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++
Sbjct: 450 TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 509
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A GH+ V+ +I G +N AN + +T L LA G+ +
Sbjct: 510 ESEGGRTPLMKAARAGHVCTVQFLI----SKGANVNRTTAN-NDHTVLSLACAGGHLAVV 564
Query: 614 RLLIEHGSEPS 624
LL+ HG++P+
Sbjct: 565 ELLLAHGADPT 575
Score = 65.7 bits (153), Expect = 7e-10
Identities = 55/201 (27%), Positives = 97/201 (48%), Gaps = 18/201 (8%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDL--NECSALHYASSRGHQNVLLMLL 545
R GLT L A+ G A + LL+ G+++NA + + +AL A+ +GH +L+
Sbjct: 1164 RAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLI 1223
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+I+ +N NTPL LA N GHL V+ ++ +G +++ A+ TPL A
Sbjct: 1224 GRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLV----QAG--ADVDAADNRKITPLMAAF 1277
Query: 606 KWGYEGIARLLIEHGSE-PSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEV 664
+ G+ + R L++ ++ PS Y + ++LK C + + +
Sbjct: 1278 RKGHVKVVRYLVKEVNQFPS-----DSECMRYIATITDKEMLKKCHLCMESIVQAKDRQ- 1331
Query: 665 KKISCESEKPTSLKLQNLTLK 685
+ E+ K S+ L+ L L+
Sbjct: 1332 ---AAEANKNASILLEELDLE 1349
Score = 62.9 bits (146), Expect = 5e-09
Identities = 43/130 (33%), Positives = 68/130 (52%), Gaps = 3/130 (2%)
Query: 760 DVNV-CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
D+N ++N TAL A G E ++L+ +ANV R K TPL AA V R
Sbjct: 1126 DINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGR 1185
Query: 819 LLLDNGANINA--IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD GA++NA + +R+T L A++ G+ ++L+ I + N T L +A +
Sbjct: 1186 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAAN 1245
Query: 877 KVHLTIIDLI 886
HL ++ L+
Sbjct: 1246 GGHLDVVQLL 1255
Score = 62.5 bits (145), Expect = 6e-09
Identities = 44/132 (33%), Positives = 68/132 (51%), Gaps = 2/132 (1%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D D +SN TAL A G +E L+ A++ R+KK TPL LAA V+
Sbjct: 957 DIDAQT-ESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVV 1015
Query: 818 RLLLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLDNGA+I A + ++TPL A G ++LL+ + N ++ T L++A
Sbjct: 1016 EILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAAS 1075
Query: 877 KVHLTIIDLIDN 888
++ II ++ N
Sbjct: 1076 GGYVNIIKILLN 1087
Score = 62.5 bits (145), Expect = 6e-09
Identities = 39/131 (29%), Positives = 69/131 (52%), Gaps = 8/131 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL +A G+ +V LL+ + + + L A+S G+ V +LL GA++N
Sbjct: 1137 TALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 1196
Query: 554 KNI--DKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ ++T L +A + GH + +I GR +I+ N+ GNTPL LA+ G+
Sbjct: 1197 PPVPSSRDTALTIAADKGHYKFCELLI------GRGAHIDVRNKKGNTPLWLAANGGHLD 1250
Query: 612 IARLLIEHGSE 622
+ +LL++ G++
Sbjct: 1251 VVQLLVQAGAD 1261
Score = 60.1 bits (139), Expect = 3e-08
Identities = 46/159 (28%), Positives = 78/159 (49%), Gaps = 8/159 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLHSGAN 550
G++ L +A+++G V+ LL+MGS+INA + N +AL A +G V+ +LL AN
Sbjct: 1101 GISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKAN 1160
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ + TPL A + G+ + ++ G +N S +T L +A+ G+
Sbjct: 1161 VEHRAKTGLTPLMEAASGGYAEVGRVLL----DKGADVNAPPVPSSRDTALTIAADKGHY 1216
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHN---LRILQVL 646
LLI G+ ++N T A N L ++Q+L
Sbjct: 1217 KFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLL 1255
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/142 (31%), Positives = 69/142 (48%), Gaps = 7/142 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++ S G TAL A G +V+ LLE G+ I + N + L A S GH V +L
Sbjct: 211 VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLL 270
Query: 545 LHSGANIN-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L +GA IN N K + L LA GHL V+ ++ K + +T L
Sbjct: 271 LENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHK------TDEMHTALME 324
Query: 604 ASKWGYEGIARLLIEHGSEPSL 625
A G+ +ARLL++ G++ ++
Sbjct: 325 ACMDGHVEVARLLLDSGAQVNM 346
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/127 (31%), Positives = 64/127 (50%), Gaps = 7/127 (5%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L +A G+ +VE LL G+ ++++ + L A+S G+ N++ +LL++GA IN
Sbjct: 1035 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS 1094
Query: 554 KNIDK--NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ K +PL LA NGH VK ++ +I N NT L LA G
Sbjct: 1095 RTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETN-----RNTALTLACFQGRTE 1149
Query: 612 IARLLIE 618
+ LL++
Sbjct: 1150 VVSLLLD 1156
Score = 54.4 bits (125), Expect = 2e-06
Identities = 79/346 (22%), Positives = 141/346 (40%), Gaps = 16/346 (4%)
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
Q + +T L LA GH V+ ++ R +I ++ G TPL LA+ G+ G+
Sbjct: 961 QTESNHDTALTLACAGGHEELVQTLLE------RGASIEHRDKKGFTPLILAATAGHVGV 1014
Query: 613 ARLLIEHGSEPSLQNSYHK-TAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCES 671
+L+++G++ Q+ K T A + +V++ H S+ +S +
Sbjct: 1015 VEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAA 1074
Query: 672 EKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAP 731
++ L ++ N S+T L + +L A++ G A + +D + I
Sbjct: 1075 SGGYVNIIKILLNAGAEIN--SRTGSKLGISPLMLAAMN-GHT--AAVKLLLDMGSDINA 1129
Query: 732 DKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCD--SNGFTALHYAARYGLDEFCNILIF 789
E + + L Q D NV G T L AA G E +L+
Sbjct: 1130 QIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLD 1189
Query: 790 NRANVNCRN--KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNI 847
A+VN T L +AA LL+ GA+I+ + NTPL A+ G++
Sbjct: 1190 KGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHL 1249
Query: 848 GAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKY 893
++L+ D+ + + T L A K H+ ++ + N++
Sbjct: 1250 DVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQF 1295
Score = 52.4 bits (120), Expect = 7e-06
Identities = 97/404 (24%), Positives = 160/404 (39%), Gaps = 34/404 (8%)
Query: 504 KATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLH 563
+A T + S NA + S L A S G N + LL G ++N+ + + L
Sbjct: 98 EAAAALTRMRAESTANAGQSDNRS-LAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLC 156
Query: 564 LAVNNGHLHCVKAIIYFAEHSGRKININCANESGN-TPLHLASKWGYEGIARLLIEHGSE 622
LA + G+ + ++ A H+ N+ G+ T L A+ G+ I +LL+ H ++
Sbjct: 157 LACSAGYYELAQVLL--AMHA----NVEDRGIKGDITSLMAAANGGHVKIVKLLLAHKAD 210
Query: 623 PSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNL 682
+ Q+S TA YA C + + + I +E + ++
Sbjct: 211 VNAQSSTGNTALTYA-----------CAGGYVDVVKVLLESGASIEDHNENGHTPLME-- 257
Query: 683 TLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI----APDKEKSNS 738
A +EN I + LAC+ +++ F+ A + K++
Sbjct: 258 AGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDE 317
Query: 739 LCHPLCE-CQYCKRKTESC---TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANV 794
+ L E C + + VN+ + + L AA G E +LI A++
Sbjct: 318 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASL 377
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA-IDVARNTPLHDASETGNIGAAKIL 853
N + TPL AA ++ LLL GANINA + + T L A G + A L
Sbjct: 378 EEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFL 437
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANKYANT 896
+ DI L T L A + HL ++ L+ AN +A T
Sbjct: 438 IKAGADIEL---GCSTPLMEAAQEGHLELVKYLLAAGANVHATT 478
Score = 50.0 bits (114), Expect = 4e-05
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ + G TAL YA G + ++L+ A++ ++ +TPL AA ++
Sbjct: 473 NVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQF 532
Query: 820 LLDNGANINAIDVAR-NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
L+ GAN+N +T L A G++ ++LL++ D T T L A
Sbjct: 533 LISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGG 592
Query: 879 HLTIIDLIDNYAN 891
H +++ + +Y N
Sbjct: 593 HTSVVCYLLDYPN 605
Score = 48.4 bits (110), Expect = 1e-04
Identities = 29/96 (30%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +SRD TAL +A+ G E L+ G+ I+ + + L A++ GH +V+
Sbjct: 1198 PVPSSRD----TALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQ 1253
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+L+ +GA+++ + K TPL A GH+ V+ ++
Sbjct: 1254 LLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLV 1289
Score = 46.0 bits (104), Expect = 6e-04
Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 7/129 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G TAL A +G + + LL+ G+++ + L A+ GH + L+ GAN+
Sbjct: 481 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANV 540
Query: 552 NQKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N+ + +T L LA GHL V+ ++ ++ + G+T L A+K G+
Sbjct: 541 NRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRL------KDGSTMLIEAAKGGHT 594
Query: 611 GIARLLIEH 619
+ L+++
Sbjct: 595 SVVCYLLDY 603
>BC107759-1|AAI07760.1| 360|Homo sapiens ankyrin repeat domain 2
(stretch responsive muscle) protein.
Length = 360
Score = 83.8 bits (198), Expect = 2e-15
Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 6/147 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D TALH AS+ G I+E LL+ G+ ++ D +C+A+H+A GH V+ +L G
Sbjct: 178 DQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHG 237
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ +TPLH+AV G + V+ + + IN + G+T LH A +
Sbjct: 238 ADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG------LEINARDREGDTALHDAVRLN 291
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFD 635
I +LL+ HG++ +N KT D
Sbjct: 292 RYKIIKLLLLHGADMMTKNLAGKTPTD 318
Score = 62.9 bits (146), Expect = 5e-09
Identities = 43/149 (28%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A++ GK ++E L G + D +ALH AS GH +L LL +GA ++ ++
Sbjct: 155 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 214
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
T +H A GHL VK + + G N+ ++ +TPLH+A + G I +
Sbjct: 215 CTAMHWACRGGHLEVVKLL----QSHGADTNVR--DKLLSTPLHVAVRTGQVEIVEHFLS 268
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G E + ++ TA A L +++K
Sbjct: 269 LGLEINARDREGDTALHDAVRLNRYKIIK 297
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/100 (35%), Positives = 49/100 (49%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TA+H+A R G E +L + A+ N R+K TPLH+A + ++ L G INA
Sbjct: 216 TAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINA 275
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKT 869
D +T LHDA K+LL + D+ N KT
Sbjct: 276 RDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKT 315
Score = 56.0 bits (129), Expect = 6e-07
Identities = 40/125 (32%), Positives = 58/125 (46%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
+ CD TALH A+ G E L+ N A V+ +++ T +H A V++LL
Sbjct: 175 DTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQ 234
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+GA+ N D +TPLH A TG + + LS +I + TAL A
Sbjct: 235 SHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYK 294
Query: 882 IIDLI 886
II L+
Sbjct: 295 IIKLL 299
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/77 (40%), Positives = 40/77 (51%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
RD T LHVA G+ IVE L +G EINA D +ALH A ++ +LL
Sbjct: 243 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 302
Query: 548 GANINQKNIDKNTPLHL 564
GA++ KN+ TP L
Sbjct: 303 GADMMTKNLAGKTPTDL 319
Score = 47.6 bits (108), Expect = 2e-04
Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 9/145 (6%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +D TA+H A G +V+ L G++ N D + LH A G ++
Sbjct: 206 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 265
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L G IN ++ + +T LH AV +K ++ H + N A G TP L
Sbjct: 266 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLL---HGADMMTKNLA---GKTPTDL 319
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNS 628
W + R +EH EP +++
Sbjct: 320 VQLW--QADTRHALEH-PEPGAEHN 341
Score = 44.8 bits (101), Expect = 0.001
Identities = 27/78 (34%), Positives = 40/78 (51%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D NV D T LH A R G E + +N R+++ T LH A N+ +I+L
Sbjct: 239 DTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKL 298
Query: 820 LLDNGANINAIDVARNTP 837
LL +GA++ ++A TP
Sbjct: 299 LLLHGADMMTKNLAGKTP 316
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA+ K VI L +G + + D R T LH AS G++ + LL + + +
Sbjct: 155 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 214
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
TA+ A HL ++ L+ ++
Sbjct: 215 CTAMHWACRGGHLEVVKLLQSH 236
>AL359388-4|CAI14194.1| 333|Homo sapiens ankyrin repeat domain 2
(stretch responsive muscle) protein.
Length = 333
Score = 83.8 bits (198), Expect = 2e-15
Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 6/147 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D TALH AS+ G I+E LL+ G+ ++ D +C+A+H+A GH V+ +L G
Sbjct: 151 DQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHG 210
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ +TPLH+AV G + V+ + + IN + G+T LH A +
Sbjct: 211 ADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG------LEINARDREGDTALHDAVRLN 264
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFD 635
I +LL+ HG++ +N KT D
Sbjct: 265 RYKIIKLLLLHGADMMTKNLAGKTPTD 291
Score = 62.9 bits (146), Expect = 5e-09
Identities = 43/149 (28%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A++ GK ++E L G + D +ALH AS GH +L LL +GA ++ ++
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
T +H A GHL VK + + G N+ ++ +TPLH+A + G I +
Sbjct: 188 CTAMHWACRGGHLEVVKLL----QSHGADTNVR--DKLLSTPLHVAVRTGQVEIVEHFLS 241
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G E + ++ TA A L +++K
Sbjct: 242 LGLEINARDREGDTALHDAVRLNRYKIIK 270
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/100 (35%), Positives = 49/100 (49%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TA+H+A R G E +L + A+ N R+K TPLH+A + ++ L G INA
Sbjct: 189 TAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINA 248
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKT 869
D +T LHDA K+LL + D+ N KT
Sbjct: 249 RDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKT 288
Score = 56.0 bits (129), Expect = 6e-07
Identities = 40/125 (32%), Positives = 58/125 (46%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
+ CD TALH A+ G E L+ N A V+ +++ T +H A V++LL
Sbjct: 148 DTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQ 207
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+GA+ N D +TPLH A TG + + LS +I + TAL A
Sbjct: 208 SHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYK 267
Query: 882 IIDLI 886
II L+
Sbjct: 268 IIKLL 272
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/77 (40%), Positives = 40/77 (51%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
RD T LHVA G+ IVE L +G EINA D +ALH A ++ +LL
Sbjct: 216 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 275
Query: 548 GANINQKNIDKNTPLHL 564
GA++ KN+ TP L
Sbjct: 276 GADMMTKNLAGKTPTDL 292
Score = 47.6 bits (108), Expect = 2e-04
Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 9/145 (6%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +D TA+H A G +V+ L G++ N D + LH A G ++
Sbjct: 179 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 238
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L G IN ++ + +T LH AV +K ++ H + N A G TP L
Sbjct: 239 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLL---HGADMMTKNLA---GKTPTDL 292
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNS 628
W + R +EH EP +++
Sbjct: 293 VQLW--QADTRHALEH-PEPGAEHN 314
Score = 44.8 bits (101), Expect = 0.001
Identities = 27/78 (34%), Positives = 40/78 (51%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D NV D T LH A R G E + +N R+++ T LH A N+ +I+L
Sbjct: 212 DTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKL 271
Query: 820 LLDNGANINAIDVARNTP 837
LL +GA++ ++A TP
Sbjct: 272 LLLHGADMMTKNLAGKTP 289
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA+ K VI L +G + + D R T LH AS G++ + LL + + +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
TA+ A HL ++ L+ ++
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSH 209
>AL355315-9|CAI15463.1| 333|Homo sapiens ankyrin repeat domain 2
(stretch responsive muscle) protein.
Length = 333
Score = 83.8 bits (198), Expect = 2e-15
Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 6/147 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D TALH AS+ G I+E LL+ G+ ++ D +C+A+H+A GH V+ +L G
Sbjct: 151 DQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHG 210
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ +TPLH+AV G + V+ + + IN + G+T LH A +
Sbjct: 211 ADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG------LEINARDREGDTALHDAVRLN 264
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFD 635
I +LL+ HG++ +N KT D
Sbjct: 265 RYKIIKLLLLHGADMMTKNLAGKTPTD 291
Score = 62.9 bits (146), Expect = 5e-09
Identities = 43/149 (28%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A++ GK ++E L G + D +ALH AS GH +L LL +GA ++ ++
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
T +H A GHL VK + + G N+ ++ +TPLH+A + G I +
Sbjct: 188 CTAMHWACRGGHLEVVKLL----QSHGADTNVR--DKLLSTPLHVAVRTGQVEIVEHFLS 241
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G E + ++ TA A L +++K
Sbjct: 242 LGLEINARDREGDTALHDAVRLNRYKIIK 270
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/100 (35%), Positives = 49/100 (49%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TA+H+A R G E +L + A+ N R+K TPLH+A + ++ L G INA
Sbjct: 189 TAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINA 248
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKT 869
D +T LHDA K+LL + D+ N KT
Sbjct: 249 RDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKT 288
Score = 56.0 bits (129), Expect = 6e-07
Identities = 40/125 (32%), Positives = 58/125 (46%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
+ CD TALH A+ G E L+ N A V+ +++ T +H A V++LL
Sbjct: 148 DTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQ 207
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+GA+ N D +TPLH A TG + + LS +I + TAL A
Sbjct: 208 SHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYK 267
Query: 882 IIDLI 886
II L+
Sbjct: 268 IIKLL 272
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/77 (40%), Positives = 40/77 (51%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
RD T LHVA G+ IVE L +G EINA D +ALH A ++ +LL
Sbjct: 216 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 275
Query: 548 GANINQKNIDKNTPLHL 564
GA++ KN+ TP L
Sbjct: 276 GADMMTKNLAGKTPTDL 292
Score = 47.6 bits (108), Expect = 2e-04
Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 9/145 (6%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +D TA+H A G +V+ L G++ N D + LH A G ++
Sbjct: 179 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 238
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L G IN ++ + +T LH AV +K ++ H + N A G TP L
Sbjct: 239 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLL---HGADMMTKNLA---GKTPTDL 292
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNS 628
W + R +EH EP +++
Sbjct: 293 VQLW--QADTRHALEH-PEPGAEHN 314
Score = 44.8 bits (101), Expect = 0.001
Identities = 27/78 (34%), Positives = 40/78 (51%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D NV D T LH A R G E + +N R+++ T LH A N+ +I+L
Sbjct: 212 DTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKL 271
Query: 820 LLDNGANINAIDVARNTP 837
LL +GA++ ++A TP
Sbjct: 272 LLLHGADMMTKNLAGKTP 289
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA+ K VI L +G + + D R T LH AS G++ + LL + + +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
TA+ A HL ++ L+ ++
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSH 209
>AJ583444-1|CAE47432.1| 449|Homo sapiens ankyrin repeat protein
protein.
Length = 449
Score = 83.8 bits (198), Expect = 2e-15
Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 6/147 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D TALH AS+ G I+E LL+ G+ ++ D +C+A+H+A GH V+ +L G
Sbjct: 267 DQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHG 326
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ +TPLH+AV G + V+ + + IN + G+T LH A +
Sbjct: 327 ADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG------LEINARDREGDTALHDAVRLN 380
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFD 635
I +LL+ HG++ +N KT D
Sbjct: 381 RYKIIKLLLLHGADMMTKNLAGKTPTD 407
Score = 62.9 bits (146), Expect = 5e-09
Identities = 43/149 (28%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A++ GK ++E L G + D +ALH AS GH +L LL +GA ++ ++
Sbjct: 244 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 303
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
T +H A GHL VK + + G N+ ++ +TPLH+A + G I +
Sbjct: 304 CTAMHWACRGGHLEVVKLL----QSHGADTNVR--DKLLSTPLHVAVRTGQVEIVEHFLS 357
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G E + ++ TA A L +++K
Sbjct: 358 LGLEINARDREGDTALHDAVRLNRYKIIK 386
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/100 (35%), Positives = 49/100 (49%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TA+H+A R G E +L + A+ N R+K TPLH+A + ++ L G INA
Sbjct: 305 TAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINA 364
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKT 869
D +T LHDA K+LL + D+ N KT
Sbjct: 365 RDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKT 404
Score = 56.0 bits (129), Expect = 6e-07
Identities = 40/125 (32%), Positives = 58/125 (46%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
+ CD TALH A+ G E L+ N A V+ +++ T +H A V++LL
Sbjct: 264 DTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQ 323
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+GA+ N D +TPLH A TG + + LS +I + TAL A
Sbjct: 324 SHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYK 383
Query: 882 IIDLI 886
II L+
Sbjct: 384 IIKLL 388
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/77 (40%), Positives = 40/77 (51%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
RD T LHVA G+ IVE L +G EINA D +ALH A ++ +LL
Sbjct: 332 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 391
Query: 548 GANINQKNIDKNTPLHL 564
GA++ KN+ TP L
Sbjct: 392 GADMMTKNLAGKTPTDL 408
Score = 47.6 bits (108), Expect = 2e-04
Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 9/145 (6%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +D TA+H A G +V+ L G++ N D + LH A G ++
Sbjct: 295 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 354
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L G IN ++ + +T LH AV +K ++ H + N A G TP L
Sbjct: 355 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLL---HGADMMTKNLA---GKTPTDL 408
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNS 628
W + R +EH EP +++
Sbjct: 409 VQLW--QADTRHALEH-PEPGAEHN 430
Score = 44.8 bits (101), Expect = 0.001
Identities = 27/78 (34%), Positives = 40/78 (51%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D NV D T LH A R G E + +N R+++ T LH A N+ +I+L
Sbjct: 328 DTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKL 387
Query: 820 LLDNGANINAIDVARNTP 837
LL +GA++ ++A TP
Sbjct: 388 LLLHGADMMTKNLAGKTP 405
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA+ K VI L +G + + D R T LH AS G++ + LL + + +
Sbjct: 244 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 303
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
TA+ A HL ++ L+ ++
Sbjct: 304 CTAMHWACRGGHLEVVKLLQSH 325
>AJ304805-1|CAC19412.1| 333|Homo sapiens skeletal muscle ankyrin
protein 2 protein.
Length = 333
Score = 83.8 bits (198), Expect = 2e-15
Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 6/147 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D TALH AS+ G I+E LL+ G+ ++ D +C+A+H+A GH V+ +L G
Sbjct: 151 DQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHG 210
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ +TPLH+AV G + V+ + + IN + G+T LH A +
Sbjct: 211 ADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG------LEINARDREGDTALHDAVRLN 264
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFD 635
I +LL+ HG++ +N KT D
Sbjct: 265 RYKIIKLLLLHGADMMTKNLAGKTPTD 291
Score = 62.9 bits (146), Expect = 5e-09
Identities = 43/149 (28%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A++ GK ++E L G + D +ALH AS GH +L LL +GA ++ ++
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
T +H A GHL VK + + G N+ ++ +TPLH+A + G I +
Sbjct: 188 CTAMHWACRGGHLEVVKLL----QSHGADTNVR--DKLLSTPLHVAVRTGQVEIVEHFLS 241
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G E + ++ TA A L +++K
Sbjct: 242 LGLEINARDREGDTALHDAVRLNRYKIIK 270
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/100 (35%), Positives = 49/100 (49%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TA+H+A R G E +L + A+ N R+K TPLH+A + ++ L G INA
Sbjct: 189 TAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINA 248
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKT 869
D +T LHDA K+LL + D+ N KT
Sbjct: 249 RDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKT 288
Score = 56.0 bits (129), Expect = 6e-07
Identities = 40/125 (32%), Positives = 58/125 (46%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
+ CD TALH A+ G E L+ N A V+ +++ T +H A V++LL
Sbjct: 148 DTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQ 207
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+GA+ N D +TPLH A TG + + LS +I + TAL A
Sbjct: 208 SHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYK 267
Query: 882 IIDLI 886
II L+
Sbjct: 268 IIKLL 272
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/77 (40%), Positives = 40/77 (51%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
RD T LHVA G+ IVE L +G EINA D +ALH A ++ +LL
Sbjct: 216 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 275
Query: 548 GANINQKNIDKNTPLHL 564
GA++ KN+ TP L
Sbjct: 276 GADMMTKNLAGKTPTDL 292
Score = 47.6 bits (108), Expect = 2e-04
Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 9/145 (6%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +D TA+H A G +V+ L G++ N D + LH A G ++
Sbjct: 179 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 238
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L G IN ++ + +T LH AV +K ++ H + N A G TP L
Sbjct: 239 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLL---HGADMMTKNLA---GKTPTDL 292
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNS 628
W + R +EH EP +++
Sbjct: 293 VQLW--QADTRHALEH-PEPGAEHN 314
Score = 44.8 bits (101), Expect = 0.001
Identities = 27/78 (34%), Positives = 40/78 (51%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D NV D T LH A R G E + +N R+++ T LH A N+ +I+L
Sbjct: 212 DTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKL 271
Query: 820 LLDNGANINAIDVARNTP 837
LL +GA++ ++A TP
Sbjct: 272 LLLHGADMMTKNLAGKTP 289
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA+ K VI L +G + + D R T LH AS G++ + LL + + +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
TA+ A HL ++ L+ ++
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSH 209
>AJ304804-1|CAC19411.1| 333|Homo sapiens skeletal muscle ankyrin
repeat protein.
Length = 333
Score = 83.8 bits (198), Expect = 2e-15
Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 6/147 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D TALH AS+ G I+E LL+ G+ ++ D +C+A+H+A GH V+ +L G
Sbjct: 151 DQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHG 210
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ +TPLH+AV G + V+ + + IN + G+T LH A +
Sbjct: 211 ADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG------LEINARDREGDTALHDAVRLN 264
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFD 635
I +LL+ HG++ +N KT D
Sbjct: 265 RYKIIKLLLLHGADMMTKNLAGKTPTD 291
Score = 62.9 bits (146), Expect = 5e-09
Identities = 43/149 (28%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A++ GK ++E L G + D +ALH AS GH +L LL +GA ++ ++
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
T +H A GHL VK + + G N+ ++ +TPLH+A + G I +
Sbjct: 188 CTAMHWACRGGHLEVVKLL----QSHGADTNVR--DKLLSTPLHVAVRTGQVEIVEHFLS 241
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G E + ++ TA A L +++K
Sbjct: 242 LGLEINARDREGDTALHDAVRLNRYKIIK 270
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/100 (35%), Positives = 49/100 (49%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TA+H+A R G E +L + A+ N R+K TPLH+A + ++ L G INA
Sbjct: 189 TAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINA 248
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKT 869
D +T LHDA K+LL + D+ N KT
Sbjct: 249 RDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKT 288
Score = 56.0 bits (129), Expect = 6e-07
Identities = 40/125 (32%), Positives = 58/125 (46%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
+ CD TALH A+ G E L+ N A V+ +++ T +H A V++LL
Sbjct: 148 DTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQ 207
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+GA+ N D +TPLH A TG + + LS +I + TAL A
Sbjct: 208 SHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYK 267
Query: 882 IIDLI 886
II L+
Sbjct: 268 IIKLL 272
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/77 (40%), Positives = 40/77 (51%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
RD T LHVA G+ IVE L +G EINA D +ALH A ++ +LL
Sbjct: 216 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 275
Query: 548 GANINQKNIDKNTPLHL 564
GA++ KN+ TP L
Sbjct: 276 GADMMTKNLAGKTPTDL 292
Score = 47.6 bits (108), Expect = 2e-04
Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 9/145 (6%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +D TA+H A G +V+ L G++ N D + LH A G ++
Sbjct: 179 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 238
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L G IN ++ + +T LH AV +K ++ H + N A G TP L
Sbjct: 239 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLL---HGADMMTKNLA---GKTPTDL 292
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNS 628
W + R +EH EP +++
Sbjct: 293 VQLW--QADTRHALEH-PEPGAEHN 314
Score = 44.8 bits (101), Expect = 0.001
Identities = 27/78 (34%), Positives = 40/78 (51%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D NV D T LH A R G E + +N R+++ T LH A N+ +I+L
Sbjct: 212 DTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKL 271
Query: 820 LLDNGANINAIDVARNTP 837
LL +GA++ ++A TP
Sbjct: 272 LLLHGADMMTKNLAGKTP 289
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA+ K VI L +G + + D R T LH AS G++ + LL + + +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
TA+ A HL ++ L+ ++
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSH 209
>AB058599-1|BAB60958.1| 333|Homo sapiens ankyrin-repeat protein
protein.
Length = 333
Score = 83.8 bits (198), Expect = 2e-15
Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 6/147 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D TALH AS+ G I+E LL+ G+ ++ D +C+A+H+A GH V+ +L G
Sbjct: 151 DQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHG 210
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N ++ +TPLH+AV G + V+ + + IN + G+T LH A +
Sbjct: 211 ADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG------LEINARDREGDTALHDAVRLN 264
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFD 635
I +LL+ HG++ +N KT D
Sbjct: 265 RYKIIKLLLLHGADMMTKNLAGKTPTD 291
Score = 62.9 bits (146), Expect = 5e-09
Identities = 43/149 (28%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A++ GK ++E L G + D +ALH AS GH +L LL +GA ++ ++
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
T +H A GHL VK + + G N+ ++ +TPLH+A + G I +
Sbjct: 188 CTAMHWACRGGHLEVVKLL----QSHGADTNVR--DKLLSTPLHVAVRTGQVEIVEHFLS 241
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G E + ++ TA A L +++K
Sbjct: 242 LGLEINARDREGDTALHDAVRLNRYKIIK 270
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/100 (35%), Positives = 49/100 (49%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TA+H+A R G E +L + A+ N R+K TPLH+A + ++ L G INA
Sbjct: 189 TAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINA 248
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKT 869
D +T LHDA K+LL + D+ N KT
Sbjct: 249 RDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKT 288
Score = 56.0 bits (129), Expect = 6e-07
Identities = 40/125 (32%), Positives = 58/125 (46%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
+ CD TALH A+ G E L+ N A V+ +++ T +H A V++LL
Sbjct: 148 DTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQ 207
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+GA+ N D +TPLH A TG + + LS +I + TAL A
Sbjct: 208 SHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYK 267
Query: 882 IIDLI 886
II L+
Sbjct: 268 IIKLL 272
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/77 (40%), Positives = 40/77 (51%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
RD T LHVA G+ IVE L +G EINA D +ALH A ++ +LL
Sbjct: 216 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 275
Query: 548 GANINQKNIDKNTPLHL 564
GA++ KN+ TP L
Sbjct: 276 GADMMTKNLAGKTPTDL 292
Score = 47.6 bits (108), Expect = 2e-04
Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 9/145 (6%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +D TA+H A G +V+ L G++ N D + LH A G ++
Sbjct: 179 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 238
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L G IN ++ + +T LH AV +K ++ H + N A G TP L
Sbjct: 239 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLL---HGADMMTKNLA---GKTPTDL 292
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNS 628
W + R +EH EP +++
Sbjct: 293 VQLW--QADTRHALEH-PEPGAEHN 314
Score = 44.8 bits (101), Expect = 0.001
Identities = 27/78 (34%), Positives = 40/78 (51%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D NV D T LH A R G E + +N R+++ T LH A N+ +I+L
Sbjct: 212 DTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKL 271
Query: 820 LLDNGANINAIDVARNTP 837
LL +GA++ ++A TP
Sbjct: 272 LLLHGADMMTKNLAGKTP 289
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA+ K VI L +G + + D R T LH AS G++ + LL + + +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
TA+ A HL ++ L+ ++
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSH 209
>U40282-1|AAC16892.1| 452|Homo sapiens integrin-linked kinase
protein.
Length = 452
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/136 (36%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Query: 503 GKATIVETLLE-MGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTP 561
G A V L+ +++N D + S LH+A G V+ ML+ GA IN N +TP
Sbjct: 11 GNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTP 70
Query: 562 LHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGS 621
LHLA ++GH V+ ++ + K +IN NE GN PLH A WG + +A L+ +G+
Sbjct: 71 LHLAASHGHRDIVQKLLQY------KADINAVNEHGNVPLHYACFWGQDQVAEDLVANGA 124
Query: 622 EPSLQNSYHKTAFDYA 637
S+ N Y + D A
Sbjct: 125 LVSICNKYGEMPVDKA 140
Score = 70.1 bits (164), Expect = 3e-11
Identities = 38/108 (35%), Positives = 59/108 (54%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
T+ D+N D +GF+ LH+A R G +LI A +N N+ TPLHLAA + +
Sbjct: 23 TENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDI 82
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLN 864
++ LL A+INA++ N PLH A G A+ L++ +++ N
Sbjct: 83 VQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130
Score = 63.3 bits (147), Expect = 4e-09
Identities = 30/77 (38%), Positives = 45/77 (58%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D HG + LH A G++ +VE L+ G+ IN + + + LH A+S GH++++ LL
Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYK 90
Query: 549 ANINQKNIDKNTPLHLA 565
A+IN N N PLH A
Sbjct: 91 ADINAVNEHGNVPLHYA 107
Score = 40.3 bits (90), Expect = 0.030
Identities = 22/59 (37%), Positives = 34/59 (57%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T LH+A+ HG IV+ LL+ ++INA + + LHYA G V L+ +GA ++
Sbjct: 69 TPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVS 127
Score = 39.5 bits (88), Expect = 0.052
Identities = 23/81 (28%), Positives = 38/81 (46%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+NV + T LH AA +G + L+ +A++N N+ PLH A + V L
Sbjct: 60 INVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDL 119
Query: 821 LDNGANINAIDVARNTPLHDA 841
+ NGA ++ + P+ A
Sbjct: 120 VANGALVSICNKYGEMPVDKA 140
Score = 37.9 bits (84), Expect = 0.16
Identities = 21/71 (29%), Positives = 34/71 (47%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + +G LHYA +G D+ L+ N A V+ NK + P+ A + ++
Sbjct: 92 DINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRER 151
Query: 820 LLDNGANINAI 830
G N+N I
Sbjct: 152 AEKMGQNLNRI 162
>CR407673-1|CAG28601.1| 452|Homo sapiens ILK protein.
Length = 452
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/136 (36%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Query: 503 GKATIVETLLE-MGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTP 561
G A V L+ +++N D + S LH+A G V+ ML+ GA IN N +TP
Sbjct: 11 GNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTP 70
Query: 562 LHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGS 621
LHLA ++GH V+ ++ + K +IN NE GN PLH A WG + +A L+ +G+
Sbjct: 71 LHLAASHGHRDIVQKLLQY------KADINAVNEHGNVPLHYACFWGQDQVAEDLVANGA 124
Query: 622 EPSLQNSYHKTAFDYA 637
S+ N Y + D A
Sbjct: 125 LVSICNKYGEMPVDKA 140
Score = 70.1 bits (164), Expect = 3e-11
Identities = 38/108 (35%), Positives = 59/108 (54%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
T+ D+N D +GF+ LH+A R G +LI A +N N+ TPLHLAA + +
Sbjct: 23 TENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDI 82
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLN 864
++ LL A+INA++ N PLH A G A+ L++ +++ N
Sbjct: 83 VQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130
Score = 63.3 bits (147), Expect = 4e-09
Identities = 30/77 (38%), Positives = 45/77 (58%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D HG + LH A G++ +VE L+ G+ IN + + + LH A+S GH++++ LL
Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYK 90
Query: 549 ANINQKNIDKNTPLHLA 565
A+IN N N PLH A
Sbjct: 91 ADINAVNEHGNVPLHYA 107
Score = 40.3 bits (90), Expect = 0.030
Identities = 22/59 (37%), Positives = 34/59 (57%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T LH+A+ HG IV+ LL+ ++INA + + LHYA G V L+ +GA ++
Sbjct: 69 TPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVS 127
Score = 39.5 bits (88), Expect = 0.052
Identities = 23/81 (28%), Positives = 38/81 (46%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+NV + T LH AA +G + L+ +A++N N+ PLH A + V L
Sbjct: 60 INVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDL 119
Query: 821 LDNGANINAIDVARNTPLHDA 841
+ NGA ++ + P+ A
Sbjct: 120 VANGALVSICNKYGEMPVDKA 140
Score = 37.9 bits (84), Expect = 0.16
Identities = 21/71 (29%), Positives = 34/71 (47%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + +G LHYA +G D+ L+ N A V+ NK + P+ A + ++
Sbjct: 92 DINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRER 151
Query: 820 LLDNGANINAI 830
G N+N I
Sbjct: 152 AEKMGQNLNRI 162
>BC062346-1|AAH62346.1| 361|Homo sapiens ankyrin repeat domain 16
protein.
Length = 361
Score = 83.4 bits (197), Expect = 3e-15
Identities = 82/304 (26%), Positives = 135/304 (44%), Gaps = 22/304 (7%)
Query: 529 LHYASSRGHQNVLLMLLHS-GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
LH A+ GH++VL L + G +I N D PLH A + GH CV+ ++ GR
Sbjct: 41 LHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLL------GRG 94
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAH---NLRILQ 644
++C ++ TPL +A G+ + L+EHG+ P L+N +F A + ILQ
Sbjct: 95 AAVDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQ 154
Query: 645 VLKSCTPNLFEYIHITSSEVKKISCESEKPTS-LKLQNLTLK-CSDTNDASKTIENLKLI 702
L + P ++ T S++++ + L+ + LK C D +
Sbjct: 155 YLLTVCPGAWK----TESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCG----V 206
Query: 703 ERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQ-YCKRKTESCTDFDV 761
++ AI G + +A ++ + A D + +L Q R S DV
Sbjct: 207 TALMDAIQCGHIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDV 266
Query: 762 NV-CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+V S TALHYAA+ G L+ A++N +++K ++ LHLA + L
Sbjct: 267 DVRATSTHLTALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFL 326
Query: 821 LDNG 824
L +G
Sbjct: 327 LQSG 330
Score = 62.5 bits (145), Expect = 6e-09
Identities = 33/96 (34%), Positives = 55/96 (57%), Gaps = 2/96 (2%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLL-EMGSEINATDLN-ECSALHYASSRGHQNVLL 542
+++ DS G ALH A++ G+ + L+ E+G +++ + +ALHYA+ GH + +
Sbjct: 232 LSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDVDVRATSTHLTALHYAAKEGHTSTIQ 291
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
LL GA+IN K+ + LHLA HL C K ++
Sbjct: 292 TLLSLGADINSKDEKNRSALHLACAGQHLACAKFLL 327
Score = 51.6 bits (118), Expect = 1e-05
Identities = 73/299 (24%), Positives = 104/299 (34%), Gaps = 12/299 (4%)
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
+T LH A +GH + Y AE G ++I N PLH A+ G+ R L+
Sbjct: 38 DTLLHCAARHGHRD---VLAYLAEAWG--MDIEATNRDYKRPLHEAASMGHRDCVRYLLG 92
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLK 678
G+ T A + L V++ + + S + L
Sbjct: 93 RGAAVDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLI 152
Query: 679 LQNLTLKCSDTNDASKTIENLKLIERILRA-ISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
LQ L C I L + + V L DY
Sbjct: 153 LQYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDA 212
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRA-NVNC 796
C + + + +C + DS G ALH AA G DE L+ +V+
Sbjct: 213 IQCGHIDVARLLLDEHGACLSAE----DSLGAQALHRAAVTGQDEAIRFLVSELGVDVDV 268
Query: 797 RNKKAQ-TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
R T LH AA T I+ LL GA+IN+ D + LH A ++ AK LL
Sbjct: 269 RATSTHLTALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLL 327
Score = 50.8 bits (116), Expect = 2e-05
Identities = 45/164 (27%), Positives = 76/164 (46%), Gaps = 12/164 (7%)
Query: 492 GLTALHVASIHGKATIVETLLEM-GSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
G T LH A+ HG ++ L E G +I AT+ + LH A+S GH++ + LL GA
Sbjct: 37 GDTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAA 96
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++ TPL +A +L ++ ++ EH + N+ G H+AS+ G
Sbjct: 97 VDCLKKADWTPLMMACTRKNLGVIQELV---EHGANPL---LKNKDGWNSFHIASREGDP 150
Query: 611 GIARLLI-----EHGSEPSLQNSYHKTAFDYAHNLRILQVLKSC 649
I + L+ +E ++ + TA + H + +LK C
Sbjct: 151 LILQYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLKRC 194
Score = 47.2 bits (107), Expect = 3e-04
Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 9/140 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
RD+ G+TAL A G + LL E G+ ++A D ALH A+ G + L+
Sbjct: 201 RDNCGVTALMDAIQCGHIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVS 260
Query: 547 S-GANINQKNIDKN-TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
G +++ + + T LH A GH ++ ++ +IN +E + LHLA
Sbjct: 261 ELGVDVDVRATSTHLTALHYAAKEGHTSTIQTLLSLGA------DINSKDEKNRSALHLA 314
Query: 605 SKWGYEGIARLLIEHGSEPS 624
+ A+ L++ G + S
Sbjct: 315 CAGQHLACAKFLLQSGLKDS 334
Score = 41.5 bits (93), Expect = 0.013
Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
Query: 768 GFTALHYAARYG-LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
G T LH AAR+G D + ++ N+ + PLH AA +R LL GA
Sbjct: 37 GDTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAA 96
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLN 864
++ + A TPL A N+G + L+ + + L N
Sbjct: 97 VDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKN 134
Score = 38.7 bits (86), Expect = 0.091
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 3/119 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNR-ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDN 823
D+ G TAL A + G + +L+ A ++ + LH AA+ + IR L+
Sbjct: 202 DNCGVTALMDAIQCGHIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSE 261
Query: 824 -GANINAIDVARN-TPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
G +++ + + T LH A++ G+ + LLS DI + ++AL +A HL
Sbjct: 262 LGVDVDVRATSTHLTALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHL 320
Score = 35.9 bits (79), Expect = 0.64
Identities = 33/128 (25%), Positives = 53/128 (41%), Gaps = 1/128 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ + + LH AA G + L+ A V+C K TPL +A VI+
Sbjct: 63 DIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAAVDCLKKADWTPLMMACTRKNLGVIQE 122
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNA-TEKTALAVAKDKV 878
L+++GAN + H AS G+ + LL+ P + +T L A
Sbjct: 123 LVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKIRRTPLHTAAMHG 182
Query: 879 HLTIIDLI 886
HL + ++
Sbjct: 183 HLEAVKVL 190
Score = 34.7 bits (76), Expect = 1.5
Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 6/78 (7%)
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLD--NGANINAIDVARNTPLHDASET 844
L+ + AN +NK H+A+ ++++ LL GA + R TPLH A+
Sbjct: 123 LVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKI-RRTPLHTAAMH 181
Query: 845 GNIGAAKILL---SYNPD 859
G++ A K+LL Y PD
Sbjct: 182 GHLEAVKVLLKRCQYEPD 199
>BC001554-1|AAH01554.1| 452|Homo sapiens integrin-linked kinase
protein.
Length = 452
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/136 (36%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Query: 503 GKATIVETLLE-MGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTP 561
G A V L+ +++N D + S LH+A G V+ ML+ GA IN N +TP
Sbjct: 11 GNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTP 70
Query: 562 LHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGS 621
LHLA ++GH V+ ++ + K +IN NE GN PLH A WG + +A L+ +G+
Sbjct: 71 LHLAASHGHRDIVQKLLQY------KADINAVNEHGNVPLHYACFWGQDQVAEDLVANGA 124
Query: 622 EPSLQNSYHKTAFDYA 637
S+ N Y + D A
Sbjct: 125 LVSICNKYGEMPVDKA 140
Score = 70.1 bits (164), Expect = 3e-11
Identities = 38/108 (35%), Positives = 59/108 (54%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
T+ D+N D +GF+ LH+A R G +LI A +N N+ TPLHLAA + +
Sbjct: 23 TENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDI 82
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLN 864
++ LL A+INA++ N PLH A G A+ L++ +++ N
Sbjct: 83 VQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130
Score = 63.3 bits (147), Expect = 4e-09
Identities = 30/77 (38%), Positives = 45/77 (58%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D HG + LH A G++ +VE L+ G+ IN + + + LH A+S GH++++ LL
Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYK 90
Query: 549 ANINQKNIDKNTPLHLA 565
A+IN N N PLH A
Sbjct: 91 ADINAVNEHGNVPLHYA 107
Score = 40.3 bits (90), Expect = 0.030
Identities = 22/59 (37%), Positives = 34/59 (57%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T LH+A+ HG IV+ LL+ ++INA + + LHYA G V L+ +GA ++
Sbjct: 69 TPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVS 127
Score = 39.5 bits (88), Expect = 0.052
Identities = 23/81 (28%), Positives = 38/81 (46%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+NV + T LH AA +G + L+ +A++N N+ PLH A + V L
Sbjct: 60 INVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDL 119
Query: 821 LDNGANINAIDVARNTPLHDA 841
+ NGA ++ + P+ A
Sbjct: 120 VANGALVSICNKYGEMPVDKA 140
Score = 37.9 bits (84), Expect = 0.16
Identities = 21/71 (29%), Positives = 34/71 (47%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + +G LHYA +G D+ L+ N A V+ NK + P+ A + ++
Sbjct: 92 DINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRER 151
Query: 820 LLDNGANINAI 830
G N+N I
Sbjct: 152 AEKMGQNLNRI 162
>AL137186-4|CAI41072.1| 361|Homo sapiens ankyrin repeat domain 16
protein.
Length = 361
Score = 83.4 bits (197), Expect = 3e-15
Identities = 82/304 (26%), Positives = 135/304 (44%), Gaps = 22/304 (7%)
Query: 529 LHYASSRGHQNVLLMLLHS-GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
LH A+ GH++VL L + G +I N D PLH A + GH CV+ ++ GR
Sbjct: 41 LHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLL------GRG 94
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAH---NLRILQ 644
++C ++ TPL +A G+ + L+EHG+ P L+N +F A + ILQ
Sbjct: 95 AAVDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQ 154
Query: 645 VLKSCTPNLFEYIHITSSEVKKISCESEKPTS-LKLQNLTLK-CSDTNDASKTIENLKLI 702
L + P ++ T S++++ + L+ + LK C D +
Sbjct: 155 YLLTVCPGAWK----TESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCG----V 206
Query: 703 ERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQ-YCKRKTESCTDFDV 761
++ AI G + +A ++ + A D + +L Q R S DV
Sbjct: 207 TALMDAIQCGHIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDV 266
Query: 762 NV-CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+V S TALHYAA+ G L+ A++N +++K ++ LHLA + L
Sbjct: 267 DVRATSTHLTALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFL 326
Query: 821 LDNG 824
L +G
Sbjct: 327 LQSG 330
Score = 62.5 bits (145), Expect = 6e-09
Identities = 33/96 (34%), Positives = 55/96 (57%), Gaps = 2/96 (2%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLL-EMGSEINATDLN-ECSALHYASSRGHQNVLL 542
+++ DS G ALH A++ G+ + L+ E+G +++ + +ALHYA+ GH + +
Sbjct: 232 LSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDVDVRATSTHLTALHYAAKEGHTSTIQ 291
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
LL GA+IN K+ + LHLA HL C K ++
Sbjct: 292 TLLSLGADINSKDEKNRSALHLACAGQHLACAKFLL 327
Score = 51.6 bits (118), Expect = 1e-05
Identities = 73/299 (24%), Positives = 104/299 (34%), Gaps = 12/299 (4%)
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
+T LH A +GH + Y AE G ++I N PLH A+ G+ R L+
Sbjct: 38 DTLLHCAARHGHRD---VLAYLAEAWG--MDIEATNRDYKRPLHEAASMGHRDCVRYLLG 92
Query: 619 HGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLK 678
G+ T A + L V++ + + S + L
Sbjct: 93 RGAAVDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLI 152
Query: 679 LQNLTLKCSDTNDASKTIENLKLIERILRA-ISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
LQ L C I L + + V L DY
Sbjct: 153 LQYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDA 212
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRA-NVNC 796
C + + + +C + DS G ALH AA G DE L+ +V+
Sbjct: 213 IQCGHIDVARLLLDEHGACLSAE----DSLGAQALHRAAVTGQDEAIRFLVSELGVDVDV 268
Query: 797 RNKKAQ-TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
R T LH AA T I+ LL GA+IN+ D + LH A ++ AK LL
Sbjct: 269 RATSTHLTALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLL 327
Score = 50.8 bits (116), Expect = 2e-05
Identities = 45/164 (27%), Positives = 76/164 (46%), Gaps = 12/164 (7%)
Query: 492 GLTALHVASIHGKATIVETLLEM-GSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
G T LH A+ HG ++ L E G +I AT+ + LH A+S GH++ + LL GA
Sbjct: 37 GDTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAA 96
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++ TPL +A +L ++ ++ EH + N+ G H+AS+ G
Sbjct: 97 VDCLKKADWTPLMMACTRKNLGVIQELV---EHGANPL---LKNKDGWNSFHIASREGDP 150
Query: 611 GIARLLI-----EHGSEPSLQNSYHKTAFDYAHNLRILQVLKSC 649
I + L+ +E ++ + TA + H + +LK C
Sbjct: 151 LILQYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLKRC 194
Score = 47.2 bits (107), Expect = 3e-04
Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 9/140 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
RD+ G+TAL A G + LL E G+ ++A D ALH A+ G + L+
Sbjct: 201 RDNCGVTALMDAIQCGHIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVS 260
Query: 547 S-GANINQKNIDKN-TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
G +++ + + T LH A GH ++ ++ +IN +E + LHLA
Sbjct: 261 ELGVDVDVRATSTHLTALHYAAKEGHTSTIQTLLSLGA------DINSKDEKNRSALHLA 314
Query: 605 SKWGYEGIARLLIEHGSEPS 624
+ A+ L++ G + S
Sbjct: 315 CAGQHLACAKFLLQSGLKDS 334
Score = 41.5 bits (93), Expect = 0.013
Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
Query: 768 GFTALHYAARYG-LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
G T LH AAR+G D + ++ N+ + PLH AA +R LL GA
Sbjct: 37 GDTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAA 96
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLN 864
++ + A TPL A N+G + L+ + + L N
Sbjct: 97 VDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKN 134
Score = 38.7 bits (86), Expect = 0.091
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 3/119 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNR-ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDN 823
D+ G TAL A + G + +L+ A ++ + LH AA+ + IR L+
Sbjct: 202 DNCGVTALMDAIQCGHIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSE 261
Query: 824 -GANINAIDVARN-TPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
G +++ + + T LH A++ G+ + LLS DI + ++AL +A HL
Sbjct: 262 LGVDVDVRATSTHLTALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHL 320
Score = 35.9 bits (79), Expect = 0.64
Identities = 33/128 (25%), Positives = 53/128 (41%), Gaps = 1/128 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ + + LH AA G + L+ A V+C K TPL +A VI+
Sbjct: 63 DIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAAVDCLKKADWTPLMMACTRKNLGVIQE 122
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNA-TEKTALAVAKDKV 878
L+++GAN + H AS G+ + LL+ P + +T L A
Sbjct: 123 LVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKIRRTPLHTAAMHG 182
Query: 879 HLTIIDLI 886
HL + ++
Sbjct: 183 HLEAVKVL 190
Score = 34.7 bits (76), Expect = 1.5
Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 6/78 (7%)
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLD--NGANINAIDVARNTPLHDASET 844
L+ + AN +NK H+A+ ++++ LL GA + R TPLH A+
Sbjct: 123 LVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKI-RRTPLHTAAMH 181
Query: 845 GNIGAAKILL---SYNPD 859
G++ A K+LL Y PD
Sbjct: 182 GHLEAVKVLLKRCQYEPD 199
>AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens
cDNA FLJ14518 fis, clone NT2RM1000850, weakly similar to
ANKYRIN R. ).
Length = 784
Score = 83.4 bits (197), Expect = 3e-15
Identities = 44/135 (32%), Positives = 74/135 (54%), Gaps = 5/135 (3%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
++ ++D TALH A+ +G + LLE + +N D + +H A G +N++ +
Sbjct: 496 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGLTPMHVACQHGQENIVRI 555
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL G +++ + D PLH A GHL VK + A+ G +++N G TPLHL
Sbjct: 556 LLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL---AKQPG--VSVNAQTLDGRTPLHL 610
Query: 604 ASKWGYEGIARLLIE 618
A++ G+ +AR+LI+
Sbjct: 611 AAQRGHYRVARILID 625
Score = 69.7 bits (163), Expect = 4e-11
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ G + L+++ S++N L + LH A+ GH + +LLH GA
Sbjct: 604 GRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGK 663
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
D T LHLA NGHL VK ++ K ++ T LHLA+ G+
Sbjct: 664 EAVTSDGYTALHLAARNGHLATVKLLV------EEKADVLARGPLNQTALHLAAAHGHSE 717
Query: 612 IARLLI 617
+ L+
Sbjct: 718 VVEELV 723
Score = 68.1 bits (159), Expect = 1e-10
Identities = 43/124 (34%), Positives = 61/124 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN +G T LH AA+ G ILI ++VN + AQTPLH+AA T RLL
Sbjct: 597 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLL 656
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L GA A+ T LH A+ G++ K+L+ D+ +TAL +A H
Sbjct: 657 LHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHS 716
Query: 881 TIID 884
+++
Sbjct: 717 EVVE 720
Score = 66.1 bits (154), Expect = 5e-10
Identities = 41/143 (28%), Positives = 70/143 (48%), Gaps = 7/143 (4%)
Query: 496 LHVASIHGKATIVETLLEM-GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
LH A+ G IV+ L + G +NA L+ + LH A+ RGH V +L+ +++N
Sbjct: 574 LHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVC 633
Query: 555 NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIAR 614
++ TPLH+A GH + +++ R G T LHLA++ G+ +
Sbjct: 634 SLLAQTPLHVAAETGHTSTARLLLH------RGAGKEAVTSDGYTALHLAARNGHLATVK 687
Query: 615 LLIEHGSEPSLQNSYHKTAFDYA 637
LL+E ++ + ++TA A
Sbjct: 688 LLVEEKADVLARGPLNQTALHLA 710
Score = 65.7 bits (153), Expect = 7e-10
Identities = 41/128 (32%), Positives = 64/128 (50%), Gaps = 1/128 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRA-NVNCRNKKAQTPLHLAAINNKTVVIR 818
DV++ + + LHYAA G +L +VN + +TPLHLAA V R
Sbjct: 562 DVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVAR 621
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+L+D +++N + TPLH A+ETG+ A++LL + + TAL +A
Sbjct: 622 ILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNG 681
Query: 879 HLTIIDLI 886
HL + L+
Sbjct: 682 HLATVKLL 689
Score = 65.3 bits (152), Expect = 9e-10
Identities = 36/115 (31%), Positives = 59/115 (51%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DV++ +G + LH A G +E L+ N AN N N++ TPLH+A V+
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVER 489
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LL ++NA D + T LH A++ G+ + ++LL N + ++ T + VA
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGLTPMHVA 544
Score = 64.9 bits (151), Expect = 1e-09
Identities = 38/134 (28%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +++R G T LH+A +VE LL +NA D ++ +ALH+A+ G ++
Sbjct: 464 PNLSNR--RGSTPLHMAVERRVRGVVERLLARKISVNAKDEDQWTALHFAAQNGDESSTR 521
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
+LL A++N+ + + TP+H+A +G + V+ ++ R ++++ + PLH
Sbjct: 522 LLLEKNASVNEVDFEGLTPMHVACQHGQENIVRILL------RRGVDVSLQGKDAWLPLH 575
Query: 603 LASKWGYEGIARLL 616
A+ G+ I +LL
Sbjct: 576 YAAWQGHLPIVKLL 589
Score = 62.5 bits (145), Expect = 6e-09
Identities = 38/125 (30%), Positives = 59/125 (47%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ + G T LH A + L+ + +VN +++ T LH AA N RLLL
Sbjct: 465 NLSNRRGSTPLHMAVERRVRGVVERLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLL 524
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ A++N +D TP+H A + G +ILL D++L L A + HL
Sbjct: 525 EKNASVNEVDFEGLTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLP 584
Query: 882 IIDLI 886
I+ L+
Sbjct: 585 IVKLL 589
Score = 59.7 bits (138), Expect = 5e-08
Identities = 39/135 (28%), Positives = 66/135 (48%), Gaps = 6/135 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A G+ + LL + N ++ + LH A R + V+ LL ++
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVERLLARKISV 497
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K+ D+ T LH A NG + ++ + ++N + G TP+H+A + G E
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLL------EKNASVNEVDFEGLTPMHVACQHGQEN 551
Query: 612 IARLLIEHGSEPSLQ 626
I R+L+ G + SLQ
Sbjct: 552 IVRILLRRGVDVSLQ 566
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/128 (28%), Positives = 69/128 (53%), Gaps = 3/128 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D + +TALH+AA+ G + +L+ A+VN + + TP+H+A + + ++R+L
Sbjct: 497 VNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGLTPMHVACQHGQENIVRIL 556
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNAT--EKTALAVAKDKV 878
L G +++ PLH A+ G++ K LL+ P +++ T +T L +A +
Sbjct: 557 LRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK-LLAKQPGVSVNAQTLDGRTPLHLAAQRG 615
Query: 879 HLTIIDLI 886
H + ++
Sbjct: 616 HYRVARIL 623
Score = 51.6 bits (118), Expect = 1e-05
Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 1/127 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVNVC T LH AA G +L+ A T LHLAA N ++L
Sbjct: 629 DVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKL 688
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L++ A++ A T LH A+ G+ + L+S + I L + +AL +A H
Sbjct: 689 LVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRH 747
Query: 880 LTIIDLI 886
++ +
Sbjct: 748 AQTVETL 754
Score = 44.8 bits (101), Expect = 0.001
Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 490 SHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGA 549
S G TALH+A+ +G V+ L+E +++ A +ALH A++ GH V+ L+ S
Sbjct: 668 SDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV-SAD 726
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
I+ + + LHLA H V+ ++ H
Sbjct: 727 VIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAH 760
Score = 43.6 bits (98), Expect = 0.003
Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH+A+ HG + +VE L+ I+ D SALH A+ H + LL GA+IN
Sbjct: 705 TALHLAAAHGHSEVVEELVS-ADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINL 763
Query: 554 KNI 556
+++
Sbjct: 764 QSL 766
Score = 35.5 bits (78), Expect = 0.84
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
Query: 562 LHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGS 621
LHLAV G C K ++ N N +N G+TPLH+A + G+ L+
Sbjct: 442 LHLAVEAGQEECAKWLLL------NNANPNLSNRRGSTPLHMAVERRVRGVVERLLARKI 495
Query: 622 EPSLQNSYHKTAFDYA 637
+ ++ TA +A
Sbjct: 496 SVNAKDEDQWTALHFA 511
Score = 33.1 bits (72), Expect = 4.5
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
TALH AA +G E L+ + ++ +++ + LHLAA + LL +GA+IN
Sbjct: 705 TALHLAAAHGHSEVVEELV-SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHIN 762
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/35 (48%), Positives = 21/35 (60%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDL 523
D GL+ALH+A+ A VETLL G+ IN L
Sbjct: 732 DEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSL 766
>AJ404847-1|CAB99253.1| 452|Homo sapiens integrin-linked kinase 1
protein.
Length = 452
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/136 (36%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Query: 503 GKATIVETLLE-MGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTP 561
G A V L+ +++N D + S LH+A G V+ ML+ GA IN N +TP
Sbjct: 11 GNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTP 70
Query: 562 LHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGS 621
LHLA ++GH V+ ++ + K +IN NE GN PLH A WG + +A L+ +G+
Sbjct: 71 LHLAASHGHRDIVQKLLQY------KADINAVNEHGNVPLHYACFWGQDQVAEDLVANGA 124
Query: 622 EPSLQNSYHKTAFDYA 637
S+ N Y + D A
Sbjct: 125 LVSICNKYGEMPVDKA 140
Score = 70.1 bits (164), Expect = 3e-11
Identities = 38/108 (35%), Positives = 59/108 (54%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
T+ D+N D +GF+ LH+A R G +LI A +N N+ TPLHLAA + +
Sbjct: 23 TENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDI 82
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLN 864
++ LL A+INA++ N PLH A G A+ L++ +++ N
Sbjct: 83 VQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130
Score = 63.3 bits (147), Expect = 4e-09
Identities = 30/77 (38%), Positives = 45/77 (58%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D HG + LH A G++ +VE L+ G+ IN + + + LH A+S GH++++ LL
Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYK 90
Query: 549 ANINQKNIDKNTPLHLA 565
A+IN N N PLH A
Sbjct: 91 ADINAVNEHGNVPLHYA 107
Score = 40.3 bits (90), Expect = 0.030
Identities = 22/59 (37%), Positives = 34/59 (57%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T LH+A+ HG IV+ LL+ ++INA + + LHYA G V L+ +GA ++
Sbjct: 69 TPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVS 127
Score = 39.5 bits (88), Expect = 0.052
Identities = 23/81 (28%), Positives = 38/81 (46%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+NV + T LH AA +G + L+ +A++N N+ PLH A + V L
Sbjct: 60 INVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDL 119
Query: 821 LDNGANINAIDVARNTPLHDA 841
+ NGA ++ + P+ A
Sbjct: 120 VANGALVSICNKYGEMPVDKA 140
Score = 37.9 bits (84), Expect = 0.16
Identities = 21/71 (29%), Positives = 34/71 (47%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + +G LHYA +G D+ L+ N A V+ NK + P+ A + ++
Sbjct: 92 DINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRER 151
Query: 820 LLDNGANINAI 830
G N+N I
Sbjct: 152 AEKMGQNLNRI 162
>AJ277481-1|CAB94832.1| 452|Homo sapiens integrin-linked kinase-2
protein.
Length = 452
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/136 (36%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Query: 503 GKATIVETLLE-MGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTP 561
G A V L+ +++N D + S LH+A G V+ ML+ GA IN N +TP
Sbjct: 11 GNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTP 70
Query: 562 LHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGS 621
LHLA ++GH V+ ++ + K +IN NE GN PLH A WG + +A L+ +G+
Sbjct: 71 LHLAASHGHRDIVQKLLQY------KADINAVNEHGNVPLHYACFWGQDQVAEDLVANGA 124
Query: 622 EPSLQNSYHKTAFDYA 637
S+ N Y + D A
Sbjct: 125 LVSICNKYGEMPVDKA 140
Score = 70.1 bits (164), Expect = 3e-11
Identities = 38/108 (35%), Positives = 59/108 (54%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
T+ D+N D +GF+ LH+A R G +LI A +N N+ TPLHLAA + +
Sbjct: 23 TENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDI 82
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLN 864
++ LL A+INA++ N PLH A G A+ L++ +++ N
Sbjct: 83 VQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130
Score = 63.3 bits (147), Expect = 4e-09
Identities = 30/77 (38%), Positives = 45/77 (58%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D HG + LH A G++ +VE L+ G+ IN + + + LH A+S GH++++ LL
Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYK 90
Query: 549 ANINQKNIDKNTPLHLA 565
A+IN N N PLH A
Sbjct: 91 ADINAVNEHGNVPLHYA 107
Score = 40.3 bits (90), Expect = 0.030
Identities = 22/59 (37%), Positives = 34/59 (57%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T LH+A+ HG IV+ LL+ ++INA + + LHYA G V L+ +GA ++
Sbjct: 69 TPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVS 127
Score = 39.5 bits (88), Expect = 0.052
Identities = 23/81 (28%), Positives = 38/81 (46%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+NV + T LH AA +G + L+ +A++N N+ PLH A + V L
Sbjct: 60 INVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDL 119
Query: 821 LDNGANINAIDVARNTPLHDA 841
+ NGA ++ + P+ A
Sbjct: 120 VANGALVSICNKYGEMPVDKA 140
Score = 37.9 bits (84), Expect = 0.16
Identities = 21/71 (29%), Positives = 34/71 (47%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + +G LHYA +G D+ L+ N A V+ NK + P+ A + ++
Sbjct: 92 DINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRER 151
Query: 820 LLDNGANINAI 830
G N+N I
Sbjct: 152 AEKMGQNLNRI 162
>AF244139-1|AAF74449.1| 452|Homo sapiens integrin-linked kinase 1
protein.
Length = 452
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/136 (36%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Query: 503 GKATIVETLLE-MGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTP 561
G A V L+ +++N D + S LH+A G V+ ML+ GA IN N +TP
Sbjct: 11 GNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTP 70
Query: 562 LHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGS 621
LHLA ++GH V+ ++ + K +IN NE GN PLH A WG + +A L+ +G+
Sbjct: 71 LHLAASHGHRDIVQKLLQY------KADINAVNEHGNVPLHYACFWGQDQVAEDLVANGA 124
Query: 622 EPSLQNSYHKTAFDYA 637
S+ N Y + D A
Sbjct: 125 LVSICNKYGEMPVDKA 140
Score = 70.1 bits (164), Expect = 3e-11
Identities = 38/108 (35%), Positives = 59/108 (54%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
T+ D+N D +GF+ LH+A R G +LI A +N N+ TPLHLAA + +
Sbjct: 23 TENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDI 82
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLN 864
++ LL A+INA++ N PLH A G A+ L++ +++ N
Sbjct: 83 VQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130
Score = 63.3 bits (147), Expect = 4e-09
Identities = 30/77 (38%), Positives = 45/77 (58%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D HG + LH A G++ +VE L+ G+ IN + + + LH A+S GH++++ LL
Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYK 90
Query: 549 ANINQKNIDKNTPLHLA 565
A+IN N N PLH A
Sbjct: 91 ADINAVNEHGNVPLHYA 107
Score = 40.3 bits (90), Expect = 0.030
Identities = 22/59 (37%), Positives = 34/59 (57%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T LH+A+ HG IV+ LL+ ++INA + + LHYA G V L+ +GA ++
Sbjct: 69 TPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVS 127
Score = 39.5 bits (88), Expect = 0.052
Identities = 23/81 (28%), Positives = 38/81 (46%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+NV + T LH AA +G + L+ +A++N N+ PLH A + V L
Sbjct: 60 INVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDL 119
Query: 821 LDNGANINAIDVARNTPLHDA 841
+ NGA ++ + P+ A
Sbjct: 120 VANGALVSICNKYGEMPVDKA 140
Score = 37.9 bits (84), Expect = 0.16
Identities = 21/71 (29%), Positives = 34/71 (47%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + +G LHYA +G D+ L+ N A V+ NK + P+ A + ++
Sbjct: 92 DINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRER 151
Query: 820 LLDNGANINAI 830
G N+N I
Sbjct: 152 AEKMGQNLNRI 162
>BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 82.6 bits (195), Expect = 6e-15
Identities = 44/135 (32%), Positives = 74/135 (54%), Gaps = 5/135 (3%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
++ ++D TALH A+ +G + LLE + +N D + +H A G +N++ +
Sbjct: 496 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRI 555
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL G +++ + D PLH A GHL VK + A+ G +++N G TPLHL
Sbjct: 556 LLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL---AKQPG--VSVNAQTLDGRTPLHL 610
Query: 604 ASKWGYEGIARLLIE 618
A++ G+ +AR+LI+
Sbjct: 611 AAQRGHYRVARILID 625
Score = 69.7 bits (163), Expect = 4e-11
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ G + L+++ S++N L + LH A+ GH + +LLH GA
Sbjct: 604 GRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGK 663
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
D T LHLA NGHL VK ++ K ++ T LHLA+ G+
Sbjct: 664 EAVTSDGYTALHLAARNGHLATVKLLV------EEKADVLARGPLNQTALHLAAAHGHSE 717
Query: 612 IARLLI 617
+ L+
Sbjct: 718 VVEELV 723
Score = 69.3 bits (162), Expect = 6e-11
Identities = 37/115 (32%), Positives = 61/115 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DV++ +G + LH A G +E L+ N AN N N++ TPLH+A V+ L
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LL ++NA D + T LH A++ G+ + ++LL N + ++ +T + VA
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVA 544
Score = 68.1 bits (159), Expect = 1e-10
Identities = 43/124 (34%), Positives = 61/124 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN +G T LH AA+ G ILI ++VN + AQTPLH+AA T RLL
Sbjct: 597 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLL 656
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L GA A+ T LH A+ G++ K+L+ D+ +TAL +A H
Sbjct: 657 LHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHS 716
Query: 881 TIID 884
+++
Sbjct: 717 EVVE 720
Score = 66.1 bits (154), Expect = 5e-10
Identities = 38/134 (28%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +++R G T LH+A +VE LL +NA D ++ +ALH+A+ G ++
Sbjct: 464 PNLSNR--RGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTR 521
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
+LL A++N+ + + TP+H+A +G + V+ ++ R ++++ + PLH
Sbjct: 522 LLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL------RRGVDVSLQGKDAWLPLH 575
Query: 603 LASKWGYEGIARLL 616
A+ G+ I +LL
Sbjct: 576 YAAWQGHLPIVKLL 589
Score = 66.1 bits (154), Expect = 5e-10
Identities = 41/143 (28%), Positives = 70/143 (48%), Gaps = 7/143 (4%)
Query: 496 LHVASIHGKATIVETLLEM-GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
LH A+ G IV+ L + G +NA L+ + LH A+ RGH V +L+ +++N
Sbjct: 574 LHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVC 633
Query: 555 NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIAR 614
++ TPLH+A GH + +++ R G T LHLA++ G+ +
Sbjct: 634 SLLAQTPLHVAAETGHTSTARLLLH------RGAGKEAVTSDGYTALHLAARNGHLATVK 687
Query: 615 LLIEHGSEPSLQNSYHKTAFDYA 637
LL+E ++ + ++TA A
Sbjct: 688 LLVEEKADVLARGPLNQTALHLA 710
Score = 65.7 bits (153), Expect = 7e-10
Identities = 38/125 (30%), Positives = 60/125 (48%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ + G T LH A + +L+ + +VN +++ T LH AA N RLLL
Sbjct: 465 NLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLL 524
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ A++N +D TP+H A + G +ILL D++L L A + HL
Sbjct: 525 EKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLP 584
Query: 882 IIDLI 886
I+ L+
Sbjct: 585 IVKLL 589
Score = 65.7 bits (153), Expect = 7e-10
Identities = 41/128 (32%), Positives = 64/128 (50%), Gaps = 1/128 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRA-NVNCRNKKAQTPLHLAAINNKTVVIR 818
DV++ + + LHYAA G +L +VN + +TPLHLAA V R
Sbjct: 562 DVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVAR 621
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+L+D +++N + TPLH A+ETG+ A++LL + + TAL +A
Sbjct: 622 ILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNG 681
Query: 879 HLTIIDLI 886
HL + L+
Sbjct: 682 HLATVKLL 689
Score = 62.1 bits (144), Expect = 8e-09
Identities = 39/135 (28%), Positives = 67/135 (49%), Gaps = 6/135 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A G+ + LL + N ++ + LH A R + V+ +LL ++
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K+ D+ T LH A NG + ++ + ++N + G TP+H+A + G E
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLL------EKNASVNEVDFEGRTPMHVACQHGQEN 551
Query: 612 IARLLIEHGSEPSLQ 626
I R+L+ G + SLQ
Sbjct: 552 IVRILLRRGVDVSLQ 566
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/128 (28%), Positives = 70/128 (54%), Gaps = 3/128 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D + +TALH+AA+ G + +L+ A+VN + + +TP+H+A + + ++R+L
Sbjct: 497 VNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRIL 556
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNAT--EKTALAVAKDKV 878
L G +++ PLH A+ G++ K LL+ P +++ T +T L +A +
Sbjct: 557 LRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK-LLAKQPGVSVNAQTLDGRTPLHLAAQRG 615
Query: 879 HLTIIDLI 886
H + ++
Sbjct: 616 HYRVARIL 623
Score = 51.6 bits (118), Expect = 1e-05
Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 1/127 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVNVC T LH AA G +L+ A T LHLAA N ++L
Sbjct: 629 DVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKL 688
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L++ A++ A T LH A+ G+ + L+S + I L + +AL +A H
Sbjct: 689 LVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRH 747
Query: 880 LTIIDLI 886
++ +
Sbjct: 748 AQTVETL 754
Score = 44.8 bits (101), Expect = 0.001
Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 490 SHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGA 549
S G TALH+A+ +G V+ L+E +++ A +ALH A++ GH V+ L+ S
Sbjct: 668 SDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV-SAD 726
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
I+ + + LHLA H V+ ++ H
Sbjct: 727 VIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAH 760
Score = 43.6 bits (98), Expect = 0.003
Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH+A+ HG + +VE L+ I+ D SALH A+ H + LL GA+IN
Sbjct: 705 TALHLAAAHGHSEVVEELVS-ADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINL 763
Query: 554 KNI 556
+++
Sbjct: 764 QSL 766
Score = 37.9 bits (84), Expect = 0.16
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 562 LHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGS 621
LHLAV G C K ++ N N +N G+TPLH+A + G+ LL+
Sbjct: 442 LHLAVEAGQEECAKWLLL------NNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKI 495
Query: 622 EPSLQNSYHKTAFDYA 637
+ ++ TA +A
Sbjct: 496 SVNAKDEDQWTALHFA 511
Score = 33.1 bits (72), Expect = 4.5
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
TALH AA +G E L+ + ++ +++ + LHLAA + LL +GA+IN
Sbjct: 705 TALHLAAAHGHSEVVEELV-SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHIN 762
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/35 (48%), Positives = 21/35 (60%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDL 523
D GL+ALH+A+ A VETLL G+ IN L
Sbjct: 732 DEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSL 766
>BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 82.6 bits (195), Expect = 6e-15
Identities = 44/135 (32%), Positives = 74/135 (54%), Gaps = 5/135 (3%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
++ ++D TALH A+ +G + LLE + +N D + +H A G +N++ +
Sbjct: 496 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRI 555
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL G +++ + D PLH A GHL VK + A+ G +++N G TPLHL
Sbjct: 556 LLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL---AKQPG--VSVNAQTLDGRTPLHL 610
Query: 604 ASKWGYEGIARLLIE 618
A++ G+ +AR+LI+
Sbjct: 611 AAQRGHYRVARILID 625
Score = 69.7 bits (163), Expect = 4e-11
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ G + L+++ S++N L + LH A+ GH + +LLH GA
Sbjct: 604 GRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGK 663
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
D T LHLA NGHL VK ++ K ++ T LHLA+ G+
Sbjct: 664 EAVTSDGYTALHLAARNGHLATVKLLV------EEKADVLARGPLNQTALHLAAAHGHSE 717
Query: 612 IARLLI 617
+ L+
Sbjct: 718 VVEELV 723
Score = 69.3 bits (162), Expect = 6e-11
Identities = 37/115 (32%), Positives = 61/115 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DV++ +G + LH A G +E L+ N AN N N++ TPLH+A V+ L
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LL ++NA D + T LH A++ G+ + ++LL N + ++ +T + VA
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVA 544
Score = 68.1 bits (159), Expect = 1e-10
Identities = 43/124 (34%), Positives = 61/124 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN +G T LH AA+ G ILI ++VN + AQTPLH+AA T RLL
Sbjct: 597 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLL 656
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L GA A+ T LH A+ G++ K+L+ D+ +TAL +A H
Sbjct: 657 LHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHS 716
Query: 881 TIID 884
+++
Sbjct: 717 EVVE 720
Score = 66.1 bits (154), Expect = 5e-10
Identities = 38/134 (28%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +++R G T LH+A +VE LL +NA D ++ +ALH+A+ G ++
Sbjct: 464 PNLSNR--RGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTR 521
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
+LL A++N+ + + TP+H+A +G + V+ ++ R ++++ + PLH
Sbjct: 522 LLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL------RRGVDVSLQGKDAWLPLH 575
Query: 603 LASKWGYEGIARLL 616
A+ G+ I +LL
Sbjct: 576 YAAWQGHLPIVKLL 589
Score = 66.1 bits (154), Expect = 5e-10
Identities = 41/143 (28%), Positives = 70/143 (48%), Gaps = 7/143 (4%)
Query: 496 LHVASIHGKATIVETLLEM-GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
LH A+ G IV+ L + G +NA L+ + LH A+ RGH V +L+ +++N
Sbjct: 574 LHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVC 633
Query: 555 NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIAR 614
++ TPLH+A GH + +++ R G T LHLA++ G+ +
Sbjct: 634 SLLAQTPLHVAAETGHTSTARLLLH------RGAGKEAVTSDGYTALHLAARNGHLATVK 687
Query: 615 LLIEHGSEPSLQNSYHKTAFDYA 637
LL+E ++ + ++TA A
Sbjct: 688 LLVEEKADVLARGPLNQTALHLA 710
Score = 65.7 bits (153), Expect = 7e-10
Identities = 38/125 (30%), Positives = 60/125 (48%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ + G T LH A + +L+ + +VN +++ T LH AA N RLLL
Sbjct: 465 NLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLL 524
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ A++N +D TP+H A + G +ILL D++L L A + HL
Sbjct: 525 EKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLP 584
Query: 882 IIDLI 886
I+ L+
Sbjct: 585 IVKLL 589
Score = 65.7 bits (153), Expect = 7e-10
Identities = 41/128 (32%), Positives = 64/128 (50%), Gaps = 1/128 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRA-NVNCRNKKAQTPLHLAAINNKTVVIR 818
DV++ + + LHYAA G +L +VN + +TPLHLAA V R
Sbjct: 562 DVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVAR 621
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+L+D +++N + TPLH A+ETG+ A++LL + + TAL +A
Sbjct: 622 ILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNG 681
Query: 879 HLTIIDLI 886
HL + L+
Sbjct: 682 HLATVKLL 689
Score = 62.1 bits (144), Expect = 8e-09
Identities = 39/135 (28%), Positives = 67/135 (49%), Gaps = 6/135 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A G+ + LL + N ++ + LH A R + V+ +LL ++
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K+ D+ T LH A NG + ++ + ++N + G TP+H+A + G E
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLL------EKNASVNEVDFEGRTPMHVACQHGQEN 551
Query: 612 IARLLIEHGSEPSLQ 626
I R+L+ G + SLQ
Sbjct: 552 IVRILLRRGVDVSLQ 566
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/128 (28%), Positives = 70/128 (54%), Gaps = 3/128 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D + +TALH+AA+ G + +L+ A+VN + + +TP+H+A + + ++R+L
Sbjct: 497 VNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRIL 556
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNAT--EKTALAVAKDKV 878
L G +++ PLH A+ G++ K LL+ P +++ T +T L +A +
Sbjct: 557 LRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK-LLAKQPGVSVNAQTLDGRTPLHLAAQRG 615
Query: 879 HLTIIDLI 886
H + ++
Sbjct: 616 HYRVARIL 623
Score = 51.6 bits (118), Expect = 1e-05
Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 1/127 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVNVC T LH AA G +L+ A T LHLAA N ++L
Sbjct: 629 DVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKL 688
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L++ A++ A T LH A+ G+ + L+S + I L + +AL +A H
Sbjct: 689 LVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRH 747
Query: 880 LTIIDLI 886
++ +
Sbjct: 748 AQTVETL 754
Score = 44.8 bits (101), Expect = 0.001
Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 490 SHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGA 549
S G TALH+A+ +G V+ L+E +++ A +ALH A++ GH V+ L+ S
Sbjct: 668 SDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV-SAD 726
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
I+ + + LHLA H V+ ++ H
Sbjct: 727 VIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAH 760
Score = 43.6 bits (98), Expect = 0.003
Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH+A+ HG + +VE L+ I+ D SALH A+ H + LL GA+IN
Sbjct: 705 TALHLAAAHGHSEVVEELVS-ADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINL 763
Query: 554 KNI 556
+++
Sbjct: 764 QSL 766
Score = 37.9 bits (84), Expect = 0.16
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 562 LHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGS 621
LHLAV G C K ++ N N +N G+TPLH+A + G+ LL+
Sbjct: 442 LHLAVEAGQEECAKWLLL------NNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKI 495
Query: 622 EPSLQNSYHKTAFDYA 637
+ ++ TA +A
Sbjct: 496 SVNAKDEDQWTALHFA 511
Score = 33.1 bits (72), Expect = 4.5
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
TALH AA +G E L+ + ++ +++ + LHLAA + LL +GA+IN
Sbjct: 705 TALHLAAAHGHSEVVEELV-SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHIN 762
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/35 (48%), Positives = 21/35 (60%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDL 523
D GL+ALH+A+ A VETLL G+ IN L
Sbjct: 732 DEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSL 766
>AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein.
Length = 832
Score = 82.6 bits (195), Expect = 6e-15
Identities = 44/135 (32%), Positives = 74/135 (54%), Gaps = 5/135 (3%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
++ ++D TALH A+ +G + LLE + +N D + +H A G +N++ +
Sbjct: 544 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRI 603
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL G +++ + D PLH A GHL VK + A+ G +++N G TPLHL
Sbjct: 604 LLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL---AKQPG--VSVNAQTLDGRTPLHL 658
Query: 604 ASKWGYEGIARLLIE 618
A++ G+ +AR+LI+
Sbjct: 659 AAQRGHYRVARILID 673
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ G + L+++ S++N L + LH A+ GH + +LLH GA
Sbjct: 652 GRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGK 711
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
D T LHLA NGHL VK ++ K ++ T LHLA+ G+
Sbjct: 712 EAMTSDGYTALHLAARNGHLATVKLLV------EEKADVLARGPLNQTALHLAAAHGHSE 765
Query: 612 IARLLI 617
+ L+
Sbjct: 766 VVEELV 771
Score = 69.3 bits (162), Expect = 6e-11
Identities = 37/115 (32%), Positives = 61/115 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DV++ +G + LH A G +E L+ N AN N N++ TPLH+A V+ L
Sbjct: 478 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 537
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LL ++NA D + T LH A++ G+ + ++LL N + ++ +T + VA
Sbjct: 538 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVA 592
Score = 67.3 bits (157), Expect = 2e-10
Identities = 43/124 (34%), Positives = 61/124 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN +G T LH AA+ G ILI ++VN + AQTPLH+AA T RLL
Sbjct: 645 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLL 704
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L GA A+ T LH A+ G++ K+L+ D+ +TAL +A H
Sbjct: 705 LHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHS 764
Query: 881 TIID 884
+++
Sbjct: 765 EVVE 768
Score = 66.1 bits (154), Expect = 5e-10
Identities = 38/134 (28%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +++R G T LH+A +VE LL +NA D ++ +ALH+A+ G ++
Sbjct: 512 PNLSNR--RGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTR 569
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
+LL A++N+ + + TP+H+A +G + V+ ++ R ++++ + PLH
Sbjct: 570 LLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL------RRGVDVSLQGKDAWLPLH 623
Query: 603 LASKWGYEGIARLL 616
A+ G+ I +LL
Sbjct: 624 YAAWQGHLPIVKLL 637
Score = 66.1 bits (154), Expect = 5e-10
Identities = 41/128 (32%), Positives = 64/128 (50%), Gaps = 1/128 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRA-NVNCRNKKAQTPLHLAAINNKTVVIR 818
DV++ + + LHYAA G +L +VN + +TPLHLAA V R
Sbjct: 610 DVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVAR 669
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+L+D +++N + TPLH A+ETG+ A++LL + + TAL +A
Sbjct: 670 ILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNG 729
Query: 879 HLTIIDLI 886
HL + L+
Sbjct: 730 HLATVKLL 737
Score = 65.7 bits (153), Expect = 7e-10
Identities = 38/125 (30%), Positives = 60/125 (48%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ + G T LH A + +L+ + +VN +++ T LH AA N RLLL
Sbjct: 513 NLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLL 572
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ A++N +D TP+H A + G +ILL D++L L A + HL
Sbjct: 573 EKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLP 632
Query: 882 IIDLI 886
I+ L+
Sbjct: 633 IVKLL 637
Score = 65.7 bits (153), Expect = 7e-10
Identities = 41/143 (28%), Positives = 70/143 (48%), Gaps = 7/143 (4%)
Query: 496 LHVASIHGKATIVETLLEM-GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
LH A+ G IV+ L + G +NA L+ + LH A+ RGH V +L+ +++N
Sbjct: 622 LHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVC 681
Query: 555 NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIAR 614
++ TPLH+A GH + +++ R G T LHLA++ G+ +
Sbjct: 682 SLLAQTPLHVAAETGHTSTARLLLH------RGAGKEAMTSDGYTALHLAARNGHLATVK 735
Query: 615 LLIEHGSEPSLQNSYHKTAFDYA 637
LL+E ++ + ++TA A
Sbjct: 736 LLVEEKADVLARGPLNQTALHLA 758
Score = 62.1 bits (144), Expect = 8e-09
Identities = 39/135 (28%), Positives = 67/135 (49%), Gaps = 6/135 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A G+ + LL + N ++ + LH A R + V+ +LL ++
Sbjct: 486 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 545
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K+ D+ T LH A NG + ++ + ++N + G TP+H+A + G E
Sbjct: 546 NAKDEDQWTALHFAAQNGDESSTRLLL------EKNASVNEVDFEGRTPMHVACQHGQEN 599
Query: 612 IARLLIEHGSEPSLQ 626
I R+L+ G + SLQ
Sbjct: 600 IVRILLRRGVDVSLQ 614
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/128 (28%), Positives = 70/128 (54%), Gaps = 3/128 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D + +TALH+AA+ G + +L+ A+VN + + +TP+H+A + + ++R+L
Sbjct: 545 VNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRIL 604
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNAT--EKTALAVAKDKV 878
L G +++ PLH A+ G++ K LL+ P +++ T +T L +A +
Sbjct: 605 LRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK-LLAKQPGVSVNAQTLDGRTPLHLAAQRG 663
Query: 879 HLTIIDLI 886
H + ++
Sbjct: 664 HYRVARIL 671
Score = 52.4 bits (120), Expect = 7e-06
Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 1/127 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVNVC T LH AA G +L+ A T LHLAA N ++L
Sbjct: 677 DVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKL 736
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L++ A++ A T LH A+ G+ + L+S + I L + +AL +A H
Sbjct: 737 LVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRH 795
Query: 880 LTIIDLI 886
++ +
Sbjct: 796 AQTVETL 802
Score = 44.8 bits (101), Expect = 0.001
Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 490 SHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGA 549
S G TALH+A+ +G V+ L+E +++ A +ALH A++ GH V+ L+ S
Sbjct: 716 SDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV-SAD 774
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
I+ + + LHLA H V+ ++ H
Sbjct: 775 VIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAH 808
Score = 43.6 bits (98), Expect = 0.003
Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH+A+ HG + +VE L+ I+ D SALH A+ H + LL GA+IN
Sbjct: 753 TALHLAAAHGHSEVVEELVS-ADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINL 811
Query: 554 KNI 556
+++
Sbjct: 812 QSL 814
Score = 37.9 bits (84), Expect = 0.16
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 562 LHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGS 621
LHLAV G C K ++ N N +N G+TPLH+A + G+ LL+
Sbjct: 490 LHLAVEAGQEECAKWLLL------NNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKI 543
Query: 622 EPSLQNSYHKTAFDYA 637
+ ++ TA +A
Sbjct: 544 SVNAKDEDQWTALHFA 559
Score = 33.1 bits (72), Expect = 4.5
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
TALH AA +G E L+ + ++ +++ + LHLAA + LL +GA+IN
Sbjct: 753 TALHLAAAHGHSEVVEELV-SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHIN 810
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/35 (48%), Positives = 21/35 (60%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDL 523
D GL+ALH+A+ A VETLL G+ IN L
Sbjct: 780 DEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSL 814
>AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein.
Length = 784
Score = 82.6 bits (195), Expect = 6e-15
Identities = 44/135 (32%), Positives = 74/135 (54%), Gaps = 5/135 (3%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
++ ++D TALH A+ +G + LLE + +N D + +H A G +N++ +
Sbjct: 496 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRI 555
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL G +++ + D PLH A GHL VK + A+ G +++N G TPLHL
Sbjct: 556 LLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL---AKQPG--VSVNAQTLDGRTPLHL 610
Query: 604 ASKWGYEGIARLLIE 618
A++ G+ +AR+LI+
Sbjct: 611 AAQRGHYRVARILID 625
Score = 69.7 bits (163), Expect = 4e-11
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ G + L+++ S++N L + LH A+ GH + +LLH GA
Sbjct: 604 GRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGK 663
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
D T LHLA NGHL VK ++ K ++ T LHLA+ G+
Sbjct: 664 KAVTSDGYTALHLAARNGHLATVKLLV------EEKADVLARGPLNQTALHLAAAHGHSE 717
Query: 612 IARLLI 617
+ L+
Sbjct: 718 VVEELV 723
Score = 69.3 bits (162), Expect = 6e-11
Identities = 37/115 (32%), Positives = 61/115 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DV++ +G + LH A G +E L+ N AN N N++ TPLH+A V+ L
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LL ++NA D + T LH A++ G+ + ++LL N + ++ +T + VA
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVA 544
Score = 68.1 bits (159), Expect = 1e-10
Identities = 43/124 (34%), Positives = 61/124 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN +G T LH AA+ G ILI ++VN + AQTPLH+AA T RLL
Sbjct: 597 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLL 656
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L GA A+ T LH A+ G++ K+L+ D+ +TAL +A H
Sbjct: 657 LHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHS 716
Query: 881 TIID 884
+++
Sbjct: 717 EVVE 720
Score = 67.7 bits (158), Expect = 2e-10
Identities = 42/143 (29%), Positives = 73/143 (51%), Gaps = 7/143 (4%)
Query: 496 LHVASIHGKATIVETLLEM-GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
LH A+ G IV+ L + G +NA L+ + LH A+ RGH V +L+ +++N
Sbjct: 574 LHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVC 633
Query: 555 NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIAR 614
++ TPLH+A GH + +++ +G+K G T LHLA++ G+ +
Sbjct: 634 SLLAQTPLHVAAETGHTSTARLLLH--RGAGKK----AVTSDGYTALHLAARNGHLATVK 687
Query: 615 LLIEHGSEPSLQNSYHKTAFDYA 637
LL+E ++ + ++TA A
Sbjct: 688 LLVEEKADVLARGPLNQTALHLA 710
Score = 66.1 bits (154), Expect = 5e-10
Identities = 38/134 (28%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +++R G T LH+A +VE LL +NA D ++ +ALH+A+ G ++
Sbjct: 464 PNLSNR--RGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTR 521
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
+LL A++N+ + + TP+H+A +G + V+ ++ R ++++ + PLH
Sbjct: 522 LLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL------RRGVDVSLQGKDAWLPLH 575
Query: 603 LASKWGYEGIARLL 616
A+ G+ I +LL
Sbjct: 576 YAAWQGHLPIVKLL 589
Score = 65.7 bits (153), Expect = 7e-10
Identities = 38/125 (30%), Positives = 60/125 (48%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ + G T LH A + +L+ + +VN +++ T LH AA N RLLL
Sbjct: 465 NLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLL 524
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ A++N +D TP+H A + G +ILL D++L L A + HL
Sbjct: 525 EKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLP 584
Query: 882 IIDLI 886
I+ L+
Sbjct: 585 IVKLL 589
Score = 65.7 bits (153), Expect = 7e-10
Identities = 41/128 (32%), Positives = 64/128 (50%), Gaps = 1/128 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRA-NVNCRNKKAQTPLHLAAINNKTVVIR 818
DV++ + + LHYAA G +L +VN + +TPLHLAA V R
Sbjct: 562 DVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVAR 621
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+L+D +++N + TPLH A+ETG+ A++LL + + TAL +A
Sbjct: 622 ILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKKAVTSDGYTALHLAARNG 681
Query: 879 HLTIIDLI 886
HL + L+
Sbjct: 682 HLATVKLL 689
Score = 62.1 bits (144), Expect = 8e-09
Identities = 39/135 (28%), Positives = 67/135 (49%), Gaps = 6/135 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A G+ + LL + N ++ + LH A R + V+ +LL ++
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K+ D+ T LH A NG + ++ + ++N + G TP+H+A + G E
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLL------EKNASVNEVDFEGRTPMHVACQHGQEN 551
Query: 612 IARLLIEHGSEPSLQ 626
I R+L+ G + SLQ
Sbjct: 552 IVRILLRRGVDVSLQ 566
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/128 (28%), Positives = 70/128 (54%), Gaps = 3/128 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D + +TALH+AA+ G + +L+ A+VN + + +TP+H+A + + ++R+L
Sbjct: 497 VNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRIL 556
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNAT--EKTALAVAKDKV 878
L G +++ PLH A+ G++ K LL+ P +++ T +T L +A +
Sbjct: 557 LRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK-LLAKQPGVSVNAQTLDGRTPLHLAAQRG 615
Query: 879 HLTIIDLI 886
H + ++
Sbjct: 616 HYRVARIL 623
Score = 51.6 bits (118), Expect = 1e-05
Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 1/127 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVNVC T LH AA G +L+ A T LHLAA N ++L
Sbjct: 629 DVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKKAVTSDGYTALHLAARNGHLATVKL 688
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L++ A++ A T LH A+ G+ + L+S + I L + +AL +A H
Sbjct: 689 LVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRH 747
Query: 880 LTIIDLI 886
++ +
Sbjct: 748 AQTVETL 754
Score = 44.8 bits (101), Expect = 0.001
Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 490 SHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGA 549
S G TALH+A+ +G V+ L+E +++ A +ALH A++ GH V+ L+ S
Sbjct: 668 SDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV-SAD 726
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
I+ + + LHLA H V+ ++ H
Sbjct: 727 VIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAH 760
Score = 43.6 bits (98), Expect = 0.003
Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH+A+ HG + +VE L+ I+ D SALH A+ H + LL GA+IN
Sbjct: 705 TALHLAAAHGHSEVVEELVS-ADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINL 763
Query: 554 KNI 556
+++
Sbjct: 764 QSL 766
Score = 37.9 bits (84), Expect = 0.16
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 562 LHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGS 621
LHLAV G C K ++ N N +N G+TPLH+A + G+ LL+
Sbjct: 442 LHLAVEAGQEECAKWLLL------NNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKI 495
Query: 622 EPSLQNSYHKTAFDYA 637
+ ++ TA +A
Sbjct: 496 SVNAKDEDQWTALHFA 511
Score = 33.1 bits (72), Expect = 4.5
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
TALH AA +G E L+ + ++ +++ + LHLAA + LL +GA+IN
Sbjct: 705 TALHLAAAHGHSEVVEELV-SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHIN 762
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/35 (48%), Positives = 21/35 (60%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDL 523
D GL+ALH+A+ A VETLL G+ IN L
Sbjct: 732 DEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSL 766
>AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specificity
Ser/Thr/Tyr kinase protein.
Length = 784
Score = 82.6 bits (195), Expect = 6e-15
Identities = 44/135 (32%), Positives = 74/135 (54%), Gaps = 5/135 (3%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
++ ++D TALH A+ +G + LLE + +N D + +H A G +N++ +
Sbjct: 496 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRI 555
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL G +++ + D PLH A GHL VK + A+ G +++N G TPLHL
Sbjct: 556 LLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL---AKQPG--VSVNAQTLDGRTPLHL 610
Query: 604 ASKWGYEGIARLLIE 618
A++ G+ +AR+LI+
Sbjct: 611 AAQRGHYRVARILID 625
Score = 69.7 bits (163), Expect = 4e-11
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ G + L+++ S++N L + LH A+ GH + +LLH GA
Sbjct: 604 GRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGK 663
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
D T LHLA NGHL VK ++ K ++ T LHLA+ G+
Sbjct: 664 EAVTSDGYTALHLAARNGHLATVKLLV------EEKADVLARGPLNQTALHLAAAHGHSE 717
Query: 612 IARLLI 617
+ L+
Sbjct: 718 VVEELV 723
Score = 69.3 bits (162), Expect = 6e-11
Identities = 37/115 (32%), Positives = 61/115 (53%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DV++ +G + LH A G +E L+ N AN N N++ TPLH+A V+ L
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LL ++NA D + T LH A++ G+ + ++LL N + ++ +T + VA
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVA 544
Score = 68.1 bits (159), Expect = 1e-10
Identities = 43/124 (34%), Positives = 61/124 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN +G T LH AA+ G ILI ++VN + AQTPLH+AA T RLL
Sbjct: 597 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLL 656
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L GA A+ T LH A+ G++ K+L+ D+ +TAL +A H
Sbjct: 657 LHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHS 716
Query: 881 TIID 884
+++
Sbjct: 717 EVVE 720
Score = 66.1 bits (154), Expect = 5e-10
Identities = 38/134 (28%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +++R G T LH+A +VE LL +NA D ++ +ALH+A+ G ++
Sbjct: 464 PNLSNR--RGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTR 521
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
+LL A++N+ + + TP+H+A +G + V+ ++ R ++++ + PLH
Sbjct: 522 LLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL------RRGVDVSLQGKDAWLPLH 575
Query: 603 LASKWGYEGIARLL 616
A+ G+ I +LL
Sbjct: 576 YAAWQGHLPIVKLL 589
Score = 66.1 bits (154), Expect = 5e-10
Identities = 41/143 (28%), Positives = 70/143 (48%), Gaps = 7/143 (4%)
Query: 496 LHVASIHGKATIVETLLEM-GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
LH A+ G IV+ L + G +NA L+ + LH A+ RGH V +L+ +++N
Sbjct: 574 LHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVC 633
Query: 555 NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIAR 614
++ TPLH+A GH + +++ R G T LHLA++ G+ +
Sbjct: 634 SLLAQTPLHVAAETGHTSTARLLLH------RGAGKEAVTSDGYTALHLAARNGHLATVK 687
Query: 615 LLIEHGSEPSLQNSYHKTAFDYA 637
LL+E ++ + ++TA A
Sbjct: 688 LLVEEKADVLARGPLNQTALHLA 710
Score = 65.7 bits (153), Expect = 7e-10
Identities = 38/125 (30%), Positives = 60/125 (48%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ + G T LH A + +L+ + +VN +++ T LH AA N RLLL
Sbjct: 465 NLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLL 524
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLT 881
+ A++N +D TP+H A + G +ILL D++L L A + HL
Sbjct: 525 EKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLP 584
Query: 882 IIDLI 886
I+ L+
Sbjct: 585 IVKLL 589
Score = 65.7 bits (153), Expect = 7e-10
Identities = 41/128 (32%), Positives = 64/128 (50%), Gaps = 1/128 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRA-NVNCRNKKAQTPLHLAAINNKTVVIR 818
DV++ + + LHYAA G +L +VN + +TPLHLAA V R
Sbjct: 562 DVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVAR 621
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+L+D +++N + TPLH A+ETG+ A++LL + + TAL +A
Sbjct: 622 ILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNG 681
Query: 879 HLTIIDLI 886
HL + L+
Sbjct: 682 HLATVKLL 689
Score = 62.1 bits (144), Expect = 8e-09
Identities = 39/135 (28%), Positives = 67/135 (49%), Gaps = 6/135 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A G+ + LL + N ++ + LH A R + V+ +LL ++
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N K+ D+ T LH A NG + ++ + ++N + G TP+H+A + G E
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLL------EKNASVNEVDFEGRTPMHVACQHGQEN 551
Query: 612 IARLLIEHGSEPSLQ 626
I R+L+ G + SLQ
Sbjct: 552 IVRILLRRGVDVSLQ 566
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/128 (28%), Positives = 70/128 (54%), Gaps = 3/128 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D + +TALH+AA+ G + +L+ A+VN + + +TP+H+A + + ++R+L
Sbjct: 497 VNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRIL 556
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNAT--EKTALAVAKDKV 878
L G +++ PLH A+ G++ K LL+ P +++ T +T L +A +
Sbjct: 557 LRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK-LLAKQPGVSVNAQTLDGRTPLHLAAQRG 615
Query: 879 HLTIIDLI 886
H + ++
Sbjct: 616 HYRVARIL 623
Score = 51.6 bits (118), Expect = 1e-05
Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 1/127 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVNVC T LH AA G +L+ A T LHLAA N ++L
Sbjct: 629 DVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKL 688
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L++ A++ A T LH A+ G+ + L+S + I L + +AL +A H
Sbjct: 689 LVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRH 747
Query: 880 LTIIDLI 886
++ +
Sbjct: 748 AQTVETL 754
Score = 44.8 bits (101), Expect = 0.001
Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 490 SHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGA 549
S G TALH+A+ +G V+ L+E +++ A +ALH A++ GH V+ L+ S
Sbjct: 668 SDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV-SAD 726
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
I+ + + LHLA H V+ ++ H
Sbjct: 727 VIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAH 760
Score = 43.6 bits (98), Expect = 0.003
Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH+A+ HG + +VE L+ I+ D SALH A+ H + LL GA+IN
Sbjct: 705 TALHLAAAHGHSEVVEELVS-ADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINL 763
Query: 554 KNI 556
+++
Sbjct: 764 QSL 766
Score = 37.9 bits (84), Expect = 0.16
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 562 LHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGS 621
LHLAV G C K ++ N N +N G+TPLH+A + G+ LL+
Sbjct: 442 LHLAVEAGQEECAKWLLL------NNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKI 495
Query: 622 EPSLQNSYHKTAFDYA 637
+ ++ TA +A
Sbjct: 496 SVNAKDEDQWTALHFA 511
Score = 33.1 bits (72), Expect = 4.5
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
TALH AA +G E L+ + ++ +++ + LHLAA + LL +GA+IN
Sbjct: 705 TALHLAAAHGHSEVVEELV-SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHIN 762
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/35 (48%), Positives = 21/35 (60%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDL 523
D GL+ALH+A+ A VETLL G+ IN L
Sbjct: 732 DEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSL 766
>CR457336-1|CAG33617.1| 288|Homo sapiens ASB8 protein.
Length = 288
Score = 82.2 bits (194), Expect = 7e-15
Identities = 44/114 (38%), Positives = 65/114 (57%), Gaps = 3/114 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFC-NILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
+VN D TALHYAA DE C +L+ AN N + TPLH AA N +R
Sbjct: 78 EVNALDGYNRTALHYAAEK--DEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVR 135
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALA 872
LL++GA++NA+D +TPL A+ GN+ + ILL Y ++ ++N +T ++
Sbjct: 136 ALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPIS 189
Score = 74.1 bits (174), Expect = 2e-12
Identities = 53/170 (31%), Positives = 88/170 (51%), Gaps = 8/170 (4%)
Query: 490 SHG-LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+HG L LH A + A VE LLE G+E+NA D +ALHYA+ + + + +LL G
Sbjct: 50 THGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEK-DEACVEVLLEYG 108
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN N + +++TPLH A + CV+A++ SG ++N + + +TPL A+ G
Sbjct: 109 ANPNALDGNRDTPLHWAAFKNNAECVRALL----ESG--ASVNALDYNNDTPLSWAAMKG 162
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH 658
+L+++G+E + N +T L + + + FE +H
Sbjct: 163 NLESVSILLDYGAEVRVINLIGQTPISRLVALLVRGLGTEKEDSCFELLH 212
Score = 60.1 bits (139), Expect = 3e-08
Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D + TALH A+ +A VE LLE G+ NA D N + LH+A+ + + + LL SG
Sbjct: 83 DGYNRTALHYAAEKDEAC-VEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESG 141
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAII-YFAE 582
A++N + + +TPL A G+L V ++ Y AE
Sbjct: 142 ASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAE 176
Score = 58.0 bits (134), Expect = 1e-07
Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 2/130 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN C LH A + +L+ A VN + +T LH AA ++ V +
Sbjct: 46 DVN-CTHGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACV-EV 103
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+ GAN NA+D R+TPLH A+ N + LL + L+ T L+ A K +
Sbjct: 104 LLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGN 163
Query: 880 LTIIDLIDNY 889
L + ++ +Y
Sbjct: 164 LESVSILLDY 173
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/74 (33%), Positives = 39/74 (52%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D + T LH A+ A V LLE G+ +NA D N + L +A+ +G+ + +LL G
Sbjct: 115 DGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYG 174
Query: 549 ANINQKNIDKNTPL 562
A + N+ TP+
Sbjct: 175 AEVRVINLIGQTPI 188
>BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein.
Length = 420
Score = 82.2 bits (194), Expect = 7e-15
Identities = 44/126 (34%), Positives = 71/126 (56%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN + LHYAA G ++ +LI N + + +PLHLA +N ++RLL
Sbjct: 157 VNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLL 216
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+++ +++NA+D + TPLH A+E A +LL D+ L + KTALAVA H+
Sbjct: 217 INSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDEQGKTALAVAVRSNHV 276
Query: 881 TIIDLI 886
+++D+I
Sbjct: 277 SLVDMI 282
Score = 80.6 bits (190), Expect = 2e-14
Identities = 49/153 (32%), Positives = 80/153 (52%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +++ GLTALH A+ V+ LL GS +NA S LHYA+ G ++V +L
Sbjct: 124 LEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVL 183
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+H+G N + +PLHLAV + V+ +I ++N + TPLHLA
Sbjct: 184 IHAGGCANVVDHQGASPLHLAVRHNFPALVRLLI------NSDSDVNAVDNRQQTPLHLA 237
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
++ ++ IA +L+ G + +L++ KTA A
Sbjct: 238 AEHAWQDIADMLLIAGVDLNLRDEQGKTALAVA 270
Score = 70.5 bits (165), Expect = 2e-11
Identities = 42/132 (31%), Positives = 67/132 (50%), Gaps = 6/132 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G TA H A+ HG+ ++ L+ G + N D +ALH A+ RGH VL L+ G
Sbjct: 62 DKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIG 121
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ ++N + T LH A H CV+ ++ +G +N + + LH A+ G
Sbjct: 122 LDLEEQNAEGLTALHSAAGGSHPDCVQLLL----RAGS--TVNALTQKNLSCLHYAALSG 175
Query: 609 YEGIARLLIEHG 620
E ++R+LI G
Sbjct: 176 SEDVSRVLIHAG 187
Score = 68.1 bits (159), Expect = 1e-10
Identities = 40/150 (26%), Positives = 76/150 (50%), Gaps = 6/150 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G TALH+A+ G +++ L+++G ++ + +ALH A+ H + + +LL +
Sbjct: 94 KDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRA 153
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+ +N + LH A +G + +I H+G N+ + G +PLHLA +
Sbjct: 154 GSTVNALTQKNLSCLHYAALSGSEDVSRVLI----HAGGCANV--VDHQGASPLHLAVRH 207
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ + RLLI S+ + ++ +T A
Sbjct: 208 NFPALVRLLINSDSDVNAVDNRQQTPLHLA 237
Score = 56.0 bits (129), Expect = 6e-07
Identities = 29/90 (32%), Positives = 48/90 (53%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH+A H +V L+ S++NA D + + LH A+ Q++ MLL +G
Sbjct: 194 DHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAG 253
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
++N ++ T L +AV + H+ V II
Sbjct: 254 VDLNLRDEQGKTALAVAVRSNHVSLVDMII 283
Score = 55.6 bits (128), Expect = 7e-07
Identities = 36/137 (26%), Positives = 67/137 (48%), Gaps = 8/137 (5%)
Query: 503 GKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK--NT 560
G I++ L+ G++I+ + + LH A+ +GH VL ++ ++ ++DK T
Sbjct: 8 GHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRT 67
Query: 561 PLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHG 620
H A +G L + ++ G + N ++ GNT LHLA+ G+ + + L++ G
Sbjct: 68 AFHRAAEHGQLDALDFLV------GSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIG 121
Query: 621 SEPSLQNSYHKTAFDYA 637
+ QN+ TA A
Sbjct: 122 LDLEEQNAEGLTALHSA 138
Score = 53.2 bits (122), Expect = 4e-06
Identities = 33/127 (25%), Positives = 62/127 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ ++ G TALH AA + +L+ + VN +K + LH AA++ V R+
Sbjct: 123 DLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 182
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ G N +D +PLH A ++L++ + D+ ++ ++T L +A +
Sbjct: 183 LIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAW 242
Query: 880 LTIIDLI 886
I D++
Sbjct: 243 QDIADML 249
Score = 50.8 bits (116), Expect = 2e-05
Identities = 33/135 (24%), Positives = 63/135 (46%), Gaps = 6/135 (4%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ + L+ LH A++ G + L+ G N D S LH A ++ +
Sbjct: 156 TVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRL 215
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L++S +++N + + TPLHLA H + I +G +++N +E G T L +
Sbjct: 216 LINSDSDVNAVDNRQQTPLHLAAE----HAWQDIADMLLIAG--VDLNLRDEQGKTALAV 269
Query: 604 ASKWGYEGIARLLIE 618
A + + + ++I+
Sbjct: 270 AVRSNHVSLVDMIIK 284
Score = 50.0 bits (114), Expect = 4e-05
Identities = 28/93 (30%), Positives = 47/93 (50%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
NV D G + LH A R+ +LI + ++VN + + QTPLHLAA + + +LL
Sbjct: 191 NVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLL 250
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILL 854
G ++N D T L A + ++ +++
Sbjct: 251 IAGVDLNLRDEQGKTALAVAVRSNHVSLVDMII 283
Score = 49.2 bits (112), Expect = 6e-05
Identities = 32/121 (26%), Positives = 55/121 (45%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
E D ++ D G TA H AA +G + + L+ + + N ++K+ T LHLAA
Sbjct: 51 EDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGH 110
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
V++ L+D G ++ + T LH A+ + ++LL + L + L
Sbjct: 111 MAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHY 170
Query: 874 A 874
A
Sbjct: 171 A 171
Score = 45.2 bits (102), Expect = 0.001
Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDN--GANINAIDV 832
+A +G IL+ + A ++C +K T LH AA V+ ++++ ++ +D
Sbjct: 4 SAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDK 63
Query: 833 ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LID 887
T H A+E G + A L+ D + + TAL +A + H+ ++ L+D
Sbjct: 64 LGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 119
Score = 42.3 bits (95), Expect = 0.007
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 3/126 (2%)
Query: 764 CDS-NGFTALHYAARYGLDEFCNILIFNRANVNCRN--KKAQTPLHLAAINNKTVVIRLL 820
C+S +G T LH AA+ G ++ + +V + K +T H AA + + + L
Sbjct: 25 CESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFL 84
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ +G + N D NT LH A+ G++ + L+ D+ NA TAL A H
Sbjct: 85 VGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHP 144
Query: 881 TIIDLI 886
+ L+
Sbjct: 145 DCVQLL 150
Score = 41.9 bits (94), Expect = 0.010
Identities = 28/112 (25%), Positives = 53/112 (47%), Gaps = 4/112 (3%)
Query: 536 GHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANE 595
GH +L +L++SGA I+ ++ D T LH A GH+ ++ F + ++ ++
Sbjct: 8 GHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHV----PVLAFIMEDLEDVALDHVDK 63
Query: 596 SGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G T H A++ G L+ G + ++++ TA A + VL+
Sbjct: 64 LGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQ 115
Score = 39.1 bits (87), Expect = 0.068
Identities = 17/65 (26%), Positives = 37/65 (56%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
+D DVN D+ T LH AA + + ++L+ ++N R+++ +T L +A +N +
Sbjct: 219 SDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDEQGKTALAVAVRSNHVSL 278
Query: 817 IRLLL 821
+ +++
Sbjct: 279 VDMII 283
>BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 82.2 bits (194), Expect = 7e-15
Identities = 44/126 (34%), Positives = 71/126 (56%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN + LHYAA G ++ +LI N + + +PLHLA +N ++RLL
Sbjct: 160 VNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLL 219
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+++ +++NA+D + TPLH A+E A +LL D+ L + KTALAVA H+
Sbjct: 220 INSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDKQGKTALAVAVRSNHV 279
Query: 881 TIIDLI 886
+++D+I
Sbjct: 280 SLVDMI 285
Score = 80.6 bits (190), Expect = 2e-14
Identities = 49/153 (32%), Positives = 80/153 (52%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +++ GLTALH A+ V+ LL GS +NA S LHYA+ G ++V +L
Sbjct: 127 LEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVL 186
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+H+G N + +PLHLAV + V+ +I ++N + TPLHLA
Sbjct: 187 IHAGGCANVVDHQGASPLHLAVRHNFPALVRLLI------NSDSDVNAVDNRQQTPLHLA 240
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
++ ++ IA +L+ G + +L++ KTA A
Sbjct: 241 AEHAWQDIADMLLIAGVDLNLRDKQGKTALAVA 273
Score = 70.5 bits (165), Expect = 2e-11
Identities = 42/132 (31%), Positives = 67/132 (50%), Gaps = 6/132 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G TA H A+ HG+ ++ L+ G + N D +ALH A+ RGH VL L+ G
Sbjct: 65 DKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIG 124
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ ++N + T LH A H CV+ ++ +G +N + + LH A+ G
Sbjct: 125 LDLEEQNAEGLTALHSAAGGSHPDCVQLLL----RAGS--TVNALTQKNLSCLHYAALSG 178
Query: 609 YEGIARLLIEHG 620
E ++R+LI G
Sbjct: 179 SEDVSRVLIHAG 190
Score = 68.1 bits (159), Expect = 1e-10
Identities = 40/150 (26%), Positives = 76/150 (50%), Gaps = 6/150 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G TALH+A+ G +++ L+++G ++ + +ALH A+ H + + +LL +
Sbjct: 97 KDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRA 156
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+ +N + LH A +G + +I H+G N+ + G +PLHLA +
Sbjct: 157 GSTVNALTQKNLSCLHYAALSGSEDVSRVLI----HAGGCANV--VDHQGASPLHLAVRH 210
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ + RLLI S+ + ++ +T A
Sbjct: 211 NFPALVRLLINSDSDVNAVDNRQQTPLHLA 240
Score = 58.0 bits (134), Expect = 1e-07
Identities = 38/147 (25%), Positives = 73/147 (49%), Gaps = 8/147 (5%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+ AL +++ G I++ L+ G++I+ + + LH A+ +GH VL ++ ++
Sbjct: 1 MNALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVA 60
Query: 553 QKNIDK--NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++DK T H A +G L + ++ G + N ++ GNT LHLA+ G+
Sbjct: 61 LDHVDKLGRTAFHRAAEHGQLDALDFLV------GSGCDHNVKDKEGNTALHLAAGRGHM 114
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ + L++ G + QN+ TA A
Sbjct: 115 AVLQRLVDIGLDLEEQNAEGLTALHSA 141
Score = 56.0 bits (129), Expect = 6e-07
Identities = 29/90 (32%), Positives = 48/90 (53%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH+A H +V L+ S++NA D + + LH A+ Q++ MLL +G
Sbjct: 197 DHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAG 256
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
++N ++ T L +AV + H+ V II
Sbjct: 257 VDLNLRDKQGKTALAVAVRSNHVSLVDMII 286
Score = 53.2 bits (122), Expect = 4e-06
Identities = 33/127 (25%), Positives = 62/127 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ ++ G TALH AA + +L+ + VN +K + LH AA++ V R+
Sbjct: 126 DLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 185
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ G N +D +PLH A ++L++ + D+ ++ ++T L +A +
Sbjct: 186 LIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAW 245
Query: 880 LTIIDLI 886
I D++
Sbjct: 246 QDIADML 252
Score = 50.0 bits (114), Expect = 4e-05
Identities = 28/93 (30%), Positives = 47/93 (50%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
NV D G + LH A R+ +LI + ++VN + + QTPLHLAA + + +LL
Sbjct: 194 NVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLL 253
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILL 854
G ++N D T L A + ++ +++
Sbjct: 254 IAGVDLNLRDKQGKTALAVAVRSNHVSLVDMII 286
Score = 49.2 bits (112), Expect = 6e-05
Identities = 32/121 (26%), Positives = 55/121 (45%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
E D ++ D G TA H AA +G + + L+ + + N ++K+ T LHLAA
Sbjct: 54 EDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGH 113
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
V++ L+D G ++ + T LH A+ + ++LL + L + L
Sbjct: 114 MAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHY 173
Query: 874 A 874
A
Sbjct: 174 A 174
Score = 49.2 bits (112), Expect = 6e-05
Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 6/135 (4%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ + L+ LH A++ G + L+ G N D S LH A ++ +
Sbjct: 159 TVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRL 218
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L++S +++N + + TPLHLA H + I +G +++N ++ G T L +
Sbjct: 219 LINSDSDVNAVDNRQQTPLHLAAE----HAWQDIADMLLIAG--VDLNLRDKQGKTALAV 272
Query: 604 ASKWGYEGIARLLIE 618
A + + + ++I+
Sbjct: 273 AVRSNHVSLVDMIIK 287
Score = 46.8 bits (106), Expect = 3e-04
Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDN--GANIN 828
AL +A +G IL+ + A ++C +K T LH AA V+ ++++ ++
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 829 AIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LID 887
+D T H A+E G + A L+ D + + TAL +A + H+ ++ L+D
Sbjct: 63 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 122
Score = 42.3 bits (95), Expect = 0.007
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 3/126 (2%)
Query: 764 CDS-NGFTALHYAARYGLDEFCNILIFNRANVNCRN--KKAQTPLHLAAINNKTVVIRLL 820
C+S +G T LH AA+ G ++ + +V + K +T H AA + + + L
Sbjct: 28 CESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFL 87
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ +G + N D NT LH A+ G++ + L+ D+ NA TAL A H
Sbjct: 88 VGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHP 147
Query: 881 TIIDLI 886
+ L+
Sbjct: 148 DCVQLL 153
Score = 40.7 bits (91), Expect = 0.022
Identities = 18/65 (27%), Positives = 37/65 (56%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
+D DVN D+ T LH AA + + ++L+ ++N R+K+ +T L +A +N +
Sbjct: 222 SDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDKQGKTALAVAVRSNHVSL 281
Query: 817 IRLLL 821
+ +++
Sbjct: 282 VDMII 286
>BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 82.2 bits (194), Expect = 7e-15
Identities = 44/126 (34%), Positives = 71/126 (56%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN + LHYAA G ++ +LI N + + +PLHLA +N ++RLL
Sbjct: 160 VNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLL 219
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+++ +++NA+D + TPLH A+E A +LL D+ L + KTALAVA H+
Sbjct: 220 INSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDEQGKTALAVAVRSNHV 279
Query: 881 TIIDLI 886
+++D+I
Sbjct: 280 SLVDMI 285
Score = 80.6 bits (190), Expect = 2e-14
Identities = 49/153 (32%), Positives = 80/153 (52%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +++ GLTALH A+ V+ LL GS +NA S LHYA+ G ++V +L
Sbjct: 127 LEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVL 186
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+H+G N + +PLHLAV + V+ +I ++N + TPLHLA
Sbjct: 187 IHAGGCANVVDHQGASPLHLAVRHNFPALVRLLI------NSDSDVNAVDNRQQTPLHLA 240
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
++ ++ IA +L+ G + +L++ KTA A
Sbjct: 241 AEHAWQDIADMLLIAGVDLNLRDEQGKTALAVA 273
Score = 70.5 bits (165), Expect = 2e-11
Identities = 42/132 (31%), Positives = 67/132 (50%), Gaps = 6/132 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G TA H A+ HG+ ++ L+ G + N D +ALH A+ RGH VL L+ G
Sbjct: 65 DKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIG 124
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ ++N + T LH A H CV+ ++ +G +N + + LH A+ G
Sbjct: 125 LDLEEQNAEGLTALHSAAGGSHPDCVQLLL----RAGS--TVNALTQKNLSCLHYAALSG 178
Query: 609 YEGIARLLIEHG 620
E ++R+LI G
Sbjct: 179 SEDVSRVLIHAG 190
Score = 68.1 bits (159), Expect = 1e-10
Identities = 40/150 (26%), Positives = 76/150 (50%), Gaps = 6/150 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G TALH+A+ G +++ L+++G ++ + +ALH A+ H + + +LL +
Sbjct: 97 KDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRA 156
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+ +N + LH A +G + +I H+G N+ + G +PLHLA +
Sbjct: 157 GSTVNALTQKNLSCLHYAALSGSEDVSRVLI----HAGGCANV--VDHQGASPLHLAVRH 210
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ + RLLI S+ + ++ +T A
Sbjct: 211 NFPALVRLLINSDSDVNAVDNRQQTPLHLA 240
Score = 58.0 bits (134), Expect = 1e-07
Identities = 38/147 (25%), Positives = 73/147 (49%), Gaps = 8/147 (5%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+ AL +++ G I++ L+ G++I+ + + LH A+ +GH VL ++ ++
Sbjct: 1 MNALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVA 60
Query: 553 QKNIDK--NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++DK T H A +G L + ++ G + N ++ GNT LHLA+ G+
Sbjct: 61 LDHVDKLGRTAFHRAAEHGQLDALDFLV------GSGCDHNVKDKEGNTALHLAAGRGHM 114
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ + L++ G + QN+ TA A
Sbjct: 115 AVLQRLVDIGLDLEEQNAEGLTALHSA 141
Score = 56.0 bits (129), Expect = 6e-07
Identities = 29/90 (32%), Positives = 48/90 (53%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G + LH+A H +V L+ S++NA D + + LH A+ Q++ MLL +G
Sbjct: 197 DHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAG 256
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
++N ++ T L +AV + H+ V II
Sbjct: 257 VDLNLRDEQGKTALAVAVRSNHVSLVDMII 286
Score = 53.2 bits (122), Expect = 4e-06
Identities = 33/127 (25%), Positives = 62/127 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ ++ G TALH AA + +L+ + VN +K + LH AA++ V R+
Sbjct: 126 DLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 185
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ G N +D +PLH A ++L++ + D+ ++ ++T L +A +
Sbjct: 186 LIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAW 245
Query: 880 LTIIDLI 886
I D++
Sbjct: 246 QDIADML 252
Score = 50.8 bits (116), Expect = 2e-05
Identities = 33/135 (24%), Positives = 63/135 (46%), Gaps = 6/135 (4%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ + L+ LH A++ G + L+ G N D S LH A ++ +
Sbjct: 159 TVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRL 218
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L++S +++N + + TPLHLA H + I +G +++N +E G T L +
Sbjct: 219 LINSDSDVNAVDNRQQTPLHLAAE----HAWQDIADMLLIAG--VDLNLRDEQGKTALAV 272
Query: 604 ASKWGYEGIARLLIE 618
A + + + ++I+
Sbjct: 273 AVRSNHVSLVDMIIK 287
Score = 50.0 bits (114), Expect = 4e-05
Identities = 28/93 (30%), Positives = 47/93 (50%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
NV D G + LH A R+ +LI + ++VN + + QTPLHLAA + + +LL
Sbjct: 194 NVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLL 253
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILL 854
G ++N D T L A + ++ +++
Sbjct: 254 IAGVDLNLRDEQGKTALAVAVRSNHVSLVDMII 286
Score = 49.2 bits (112), Expect = 6e-05
Identities = 32/121 (26%), Positives = 55/121 (45%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
E D ++ D G TA H AA +G + + L+ + + N ++K+ T LHLAA
Sbjct: 54 EDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGH 113
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
V++ L+D G ++ + T LH A+ + ++LL + L + L
Sbjct: 114 MAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHY 173
Query: 874 A 874
A
Sbjct: 174 A 174
Score = 46.8 bits (106), Expect = 3e-04
Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDN--GANIN 828
AL +A +G IL+ + A ++C +K T LH AA V+ ++++ ++
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 829 AIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LID 887
+D T H A+E G + A L+ D + + TAL +A + H+ ++ L+D
Sbjct: 63 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 122
Score = 42.3 bits (95), Expect = 0.007
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 3/126 (2%)
Query: 764 CDS-NGFTALHYAARYGLDEFCNILIFNRANVNCRN--KKAQTPLHLAAINNKTVVIRLL 820
C+S +G T LH AA+ G ++ + +V + K +T H AA + + + L
Sbjct: 28 CESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFL 87
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ +G + N D NT LH A+ G++ + L+ D+ NA TAL A H
Sbjct: 88 VGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHP 147
Query: 881 TIIDLI 886
+ L+
Sbjct: 148 DCVQLL 153
Score = 39.1 bits (87), Expect = 0.068
Identities = 17/65 (26%), Positives = 37/65 (56%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
+D DVN D+ T LH AA + + ++L+ ++N R+++ +T L +A +N +
Sbjct: 222 SDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDEQGKTALAVAVRSNHVSL 281
Query: 817 IRLLL 821
+ +++
Sbjct: 282 VDMII 286
>BC001321-1|AAH01321.1| 288|Homo sapiens ankyrin repeat and SOCS
box-containing 8 protein.
Length = 288
Score = 82.2 bits (194), Expect = 7e-15
Identities = 44/114 (38%), Positives = 65/114 (57%), Gaps = 3/114 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFC-NILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
+VN D TALHYAA DE C +L+ AN N + TPLH AA N +R
Sbjct: 78 EVNALDGYNRTALHYAAEK--DEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVR 135
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALA 872
LL++GA++NA+D +TPL A+ GN+ + ILL Y ++ ++N +T ++
Sbjct: 136 ALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPIS 189
Score = 74.1 bits (174), Expect = 2e-12
Identities = 53/170 (31%), Positives = 88/170 (51%), Gaps = 8/170 (4%)
Query: 490 SHG-LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+HG L LH A + A VE LLE G+E+NA D +ALHYA+ + + + +LL G
Sbjct: 50 THGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEK-DEACVEVLLEYG 108
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN N + +++TPLH A + CV+A++ SG ++N + + +TPL A+ G
Sbjct: 109 ANPNALDGNRDTPLHWAAFKNNAECVRALL----ESG--ASVNALDYNNDTPLSWAAMKG 162
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH 658
+L+++G+E + N +T L + + + FE +H
Sbjct: 163 NLESVSILLDYGAEVRVINLIGQTPISRLVALLVRGLGTEKEDSCFELLH 212
Score = 60.1 bits (139), Expect = 3e-08
Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D + TALH A+ +A VE LLE G+ NA D N + LH+A+ + + + LL SG
Sbjct: 83 DGYNRTALHYAAEKDEAC-VEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESG 141
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAII-YFAE 582
A++N + + +TPL A G+L V ++ Y AE
Sbjct: 142 ASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAE 176
Score = 58.0 bits (134), Expect = 1e-07
Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 2/130 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN C LH A + +L+ A VN + +T LH AA ++ V +
Sbjct: 46 DVN-CTHGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACV-EV 103
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+ GAN NA+D R+TPLH A+ N + LL + L+ T L+ A K +
Sbjct: 104 LLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGN 163
Query: 880 LTIIDLIDNY 889
L + ++ +Y
Sbjct: 164 LESVSILLDY 173
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/74 (33%), Positives = 39/74 (52%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D + T LH A+ A V LLE G+ +NA D N + L +A+ +G+ + +LL G
Sbjct: 115 DGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYG 174
Query: 549 ANINQKNIDKNTPL 562
A + N+ TP+
Sbjct: 175 AEVRVINLIGQTPI 188
>AY281131-1|AAP37612.1| 1249|Homo sapiens AIDA-1b protein.
Length = 1249
Score = 82.2 bits (194), Expect = 7e-15
Identities = 45/142 (31%), Positives = 79/142 (55%), Gaps = 6/142 (4%)
Query: 515 GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCV 574
G +N TD + +ALH+A+ GH++++L LL A+ N + P+HLA G + V
Sbjct: 49 GPNVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIV 108
Query: 575 KAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAF 634
K +I+ H +N N T LH A+++G+ + +L+E ++P+++NS +T
Sbjct: 109 KILIH---HGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPL 165
Query: 635 DYA---HNLRILQVLKSCTPNL 653
D A LR+++++ S PNL
Sbjct: 166 DLAALYGRLRVVKMIISAHPNL 187
Score = 74.5 bits (175), Expect = 1e-12
Identities = 57/228 (25%), Positives = 113/228 (49%), Gaps = 17/228 (7%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +++ TALH A+ +G + +V LLE ++ + + L A+ G V+ M+
Sbjct: 121 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI 180
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ + N+ N K+TPLHLA NGH KA++ +G ++++C E G+ LH A
Sbjct: 181 ISAHPNLMSCNTRKHTPLHLAARNGH----KAVVQVLLEAG--MDVSCQTEKGSA-LHEA 233
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDY------AHNLRILQVLKSCTPNLFEYIH 658
+ +G + R+L+E G + ++++S +T D +L+I +L+ + +Y
Sbjct: 234 ALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHPSQKSLQIATLLQEYLEGVGKYAT 293
Query: 659 ITSSEVKKISCESEKPTSLKLQNLTLKCSD---TNDASKTIENLKLIE 703
+ V++ E S +++ + K T + SK ++ +KL +
Sbjct: 294 VLEEPVQE-DATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQ 340
Score = 70.9 bits (166), Expect = 2e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 9/141 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMG---SEINATDLNECSALHYASSRGHQNVLLMLL 545
D+ G +H+A+ G IV+ L+ G S +N + +ALH A+ GH V+ +LL
Sbjct: 89 DNKGYFPIHLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLL 148
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+ +N TPL LA G L VK II + H N+ N +TPLHLA+
Sbjct: 149 EELTDPTIRNSKLETPLDLAALYGRLRVVKMII--SAHP----NLMSCNTRKHTPLHLAA 202
Query: 606 KWGYEGIARLLIEHGSEPSLQ 626
+ G++ + ++L+E G + S Q
Sbjct: 203 RNGHKAVVQVLLEAGMDVSCQ 223
Score = 65.7 bits (153), Expect = 7e-10
Identities = 32/101 (31%), Positives = 57/101 (56%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN ++ TALH AA+YG E +L+ + RN K +TPL LAA+ + V++++
Sbjct: 121 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI 180
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDIT 861
+ N+ + + ++TPLH A+ G+ ++LL D++
Sbjct: 181 ISAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAGMDVS 221
Score = 65.3 bits (152), Expect = 9e-10
Identities = 39/130 (30%), Positives = 69/130 (53%), Gaps = 3/130 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN DS+G+TALH+AA G + L+ A+ N + K P+HLAA ++++
Sbjct: 51 NVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKI 110
Query: 820 LLDNGANINAIDVARN---TPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
L+ +G + + ++ N T LH A++ G+ +LL D T+ N+ +T L +A
Sbjct: 111 LIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAAL 170
Query: 877 KVHLTIIDLI 886
L ++ +I
Sbjct: 171 YGRLRVVKMI 180
Score = 64.1 bits (149), Expect = 2e-09
Identities = 43/148 (29%), Positives = 73/148 (49%), Gaps = 11/148 (7%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P + DS G TALH A+++G IV LL+ + N D +H A+ +G ++
Sbjct: 50 PNVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVK 109
Query: 543 MLLHSG---ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNT 599
+L+H G + +N++N + T LH A GH V ++ E + I N T
Sbjct: 110 ILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLL--EELTDPTIR----NSKLET 163
Query: 600 PLHLASKWGYEGIARLLIEHGSEPSLQN 627
PL LA+ +G + +++I + P+L +
Sbjct: 164 PLDLAALYGRLRVVKMII--SAHPNLMS 189
Score = 58.8 bits (136), Expect = 8e-08
Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D + +S T L AA YG ++I N+ N + TPLHLAA N V+++
Sbjct: 153 DPTIRNSKLETPLDLAALYGRLRVVKMIISAHPNLMSCNTRKHTPLHLAARNGHKAVVQV 212
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD--- 876
LL+ G +++ + + LH+A+ G + ++LL D + ++ +T L + K+
Sbjct: 213 LLEAGMDVSC-QTEKGSALHEAALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHPS 271
Query: 877 KVHLTIIDLIDNY---ANKYA 894
+ L I L+ Y KYA
Sbjct: 272 QKSLQIATLLQEYLEGVGKYA 292
Score = 56.4 bits (130), Expect = 4e-07
Identities = 36/128 (28%), Positives = 64/128 (50%), Gaps = 3/128 (2%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFN---RANVNCRNKKAQTPLHLAAINNKTVVIR 818
NV D+ G+ +H AA G E ILI + + VN +N + +T LH AA + V+
Sbjct: 86 NVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVA 145
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+LL+ + + TPL A+ G + K+++S +P++ N + T L +A
Sbjct: 146 VLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMIISAHPNLMSCNTRKHTPLHLAARNG 205
Query: 879 HLTIIDLI 886
H ++ ++
Sbjct: 206 HKAVVQVL 213
Score = 49.6 bits (113), Expect = 5e-05
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 785 NIL-IFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASE 843
N+L I+ NVNC + T LH AA+N ++ LL A+ N D P+H A+
Sbjct: 42 NLLSIWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAW 101
Query: 844 TGNIGAAKILLSYNPD---ITLLNATEKTALAVAKDKVHLTIIDLI 886
G++ KIL+ + P + N +TAL A H ++ ++
Sbjct: 102 KGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVL 147
Score = 44.4 bits (100), Expect = 0.002
Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 13/116 (11%)
Query: 542 LMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
L+ + G N+N + T LH A NGH V ++ + + + N A+ G P+
Sbjct: 43 LLSIWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQY------EASTNVADNKGYFPI 96
Query: 602 HLASKWGYEGIARLLIEHG---SEPSLQNSYHKTAF----DYAHNLRILQVLKSCT 650
HLA+ G I ++LI HG S + QN+ ++TA Y H+ + +L+ T
Sbjct: 97 HLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELT 152
Score = 43.2 bits (97), Expect = 0.004
Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 1/73 (1%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P + S ++ T LH+A+ +G +V+ LLE G +++ + SALH A+ G +V+
Sbjct: 185 PNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSC-QTEKGSALHEAALFGKVDVVR 243
Query: 543 MLLHSGANINQKN 555
+LL +G + N K+
Sbjct: 244 VLLETGIDANIKD 256
>AK024908-1|BAB15033.1| 288|Homo sapiens NP3) mRNA. protein.
Length = 288
Score = 82.2 bits (194), Expect = 7e-15
Identities = 44/114 (38%), Positives = 65/114 (57%), Gaps = 3/114 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFC-NILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
+VN D TALHYAA DE C +L+ AN N + TPLH AA N +R
Sbjct: 78 EVNALDGYNRTALHYAAEK--DEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVR 135
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALA 872
LL++GA++NA+D +TPL A+ GN+ + ILL Y ++ ++N +T ++
Sbjct: 136 ALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPIS 189
Score = 74.1 bits (174), Expect = 2e-12
Identities = 53/170 (31%), Positives = 88/170 (51%), Gaps = 8/170 (4%)
Query: 490 SHG-LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+HG L LH A + A VE LLE G+E+NA D +ALHYA+ + + + +LL G
Sbjct: 50 THGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEK-DEACVEVLLEYG 108
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
AN N + +++TPLH A + CV+A++ SG ++N + + +TPL A+ G
Sbjct: 109 ANPNALDGNRDTPLHWAAFKNNAECVRALL----ESG--ASVNALDYNNDTPLSWAAMKG 162
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIH 658
+L+++G+E + N +T L + + + FE +H
Sbjct: 163 NLESVSILLDYGAEVRVINLIGQTPISRLVALLVRGLGTEKEDSCFELLH 212
Score = 60.1 bits (139), Expect = 3e-08
Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D + TALH A+ +A VE LLE G+ NA D N + LH+A+ + + + LL SG
Sbjct: 83 DGYNRTALHYAAEKDEAC-VEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESG 141
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAII-YFAE 582
A++N + + +TPL A G+L V ++ Y AE
Sbjct: 142 ASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAE 176
Score = 58.0 bits (134), Expect = 1e-07
Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 2/130 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN C LH A + +L+ A VN + +T LH AA ++ V +
Sbjct: 46 DVN-CTHGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACV-EV 103
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL+ GAN NA+D R+TPLH A+ N + LL + L+ T L+ A K +
Sbjct: 104 LLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGN 163
Query: 880 LTIIDLIDNY 889
L + ++ +Y
Sbjct: 164 LESVSILLDY 173
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/74 (33%), Positives = 39/74 (52%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D + T LH A+ A V LLE G+ +NA D N + L +A+ +G+ + +LL G
Sbjct: 115 DGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYG 174
Query: 549 ANINQKNIDKNTPL 562
A + N+ TP+
Sbjct: 175 AEVRVINLIGQTPI 188
>BC043394-1|AAH43394.1| 751|Homo sapiens ANKRD17 protein protein.
Length = 751
Score = 81.0 bits (191), Expect = 2e-14
Identities = 93/398 (23%), Positives = 164/398 (41%), Gaps = 20/398 (5%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L A+ G IV+ LL +++NA +AL YA + G+ +V+ +LL SGA+I
Sbjct: 302 ITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIE 361
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +G IN + +NE + L LA G+ +
Sbjct: 362 DHNENGHTPLMEAGSAGHVEVARLLL----ENGAGINTH-SNEFKESALTLACYKGHLEM 416
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPNLFEYIHITSSEVKKISC 669
R L+E G++ + TA A ++ + ++L + S + +C
Sbjct: 417 VRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 476
Query: 670 ESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI 729
+ L + ND T ++ A G ++ + A I
Sbjct: 477 GGHVELAALLIERGASLEEVNDEGYT--------PLMEAAREGHEEMVALLLG--QGANI 526
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
E++ L C + ++ + T L AA+ G E L+
Sbjct: 527 NAQTEETQETALTLACCGGFLEVADFLIKAGADI-ELGCSTPLMEAAQEGHLELVKYLLA 585
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
ANV+ T L A N T V +LL GA++ TPL A+ G++
Sbjct: 586 AGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCT 645
Query: 850 AKILLSYNPDITLLNA-TEKTALAVAKDKVHLTIIDLI 886
+ L+S ++ A + T L++A HL +++L+
Sbjct: 646 VQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELL 683
Score = 68.5 bits (160), Expect = 1e-10
Identities = 43/131 (32%), Positives = 69/131 (52%), Gaps = 5/131 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A+ G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++
Sbjct: 566 TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 625
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A GH+ V+ +I G +N AN + +T L LA G+ +
Sbjct: 626 ESEGGRTPLMKAARAGHVCTVQFLI----SKGANVNRTTAN-NDHTVLSLACAGGHLAVV 680
Query: 614 RLLIEHGSEPS 624
LL+ HG++P+
Sbjct: 681 ELLLAHGADPT 691
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/142 (31%), Positives = 69/142 (48%), Gaps = 7/142 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++ S G TAL A G +V+ LLE G+ I + N + L A S GH V +L
Sbjct: 327 VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLL 386
Query: 545 LHSGANIN-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L +GA IN N K + L LA GHL V+ ++ K + +T L
Sbjct: 387 LENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHK------TDEMHTALME 440
Query: 604 ASKWGYEGIARLLIEHGSEPSL 625
A G+ +ARLL++ G++ ++
Sbjct: 441 ACMDGHVEVARLLLDSGAQVNM 462
Score = 55.6 bits (128), Expect = 7e-07
Identities = 98/404 (24%), Positives = 161/404 (39%), Gaps = 34/404 (8%)
Query: 504 KATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLH 563
+A T + S NA + S L A S G N + LL G ++N+ + + L
Sbjct: 214 EAAAALTRMRAESTANAGQSDNRS-LAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLC 272
Query: 564 LAVNNGHLHCVKAIIYFAEHSGRKININCANESGN-TPLHLASKWGYEGIARLLIEHGSE 622
LA + G+ + ++ A H+ N+ G+ TPL A+ G+ I +LL+ H ++
Sbjct: 273 LACSAGYYELAQVLL--AMHA----NVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKAD 326
Query: 623 PSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNL 682
+ Q+S TA YA C + + + I +E + ++
Sbjct: 327 VNAQSSTGNTALTYA-----------CAGGYVDVVKVLLESGASIEDHNENGHTPLME-- 373
Query: 683 TLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI----APDKEKSNS 738
A +EN I + LAC+ +++ F+ A + K++
Sbjct: 374 AGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDE 433
Query: 739 LCHPLCE-CQYCKRKTESC---TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANV 794
+ L E C + + VN+ + + L AA G E +LI A++
Sbjct: 434 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASL 493
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA-IDVARNTPLHDASETGNIGAAKIL 853
N + TPL AA ++ LLL GANINA + + T L A G + A L
Sbjct: 494 EEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFL 553
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANKYANT 896
+ DI L T L A + HL ++ L+ AN +A T
Sbjct: 554 IKAGADIEL---GCSTPLMEAAQEGHLELVKYLLAAGANVHATT 594
Score = 50.0 bits (114), Expect = 4e-05
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ + G TAL YA G + ++L+ A++ ++ +TPL AA ++
Sbjct: 589 NVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQF 648
Query: 820 LLDNGANINAIDVAR-NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
L+ GAN+N +T L A G++ ++LL++ D T T L A
Sbjct: 649 LISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGG 708
Query: 879 HLTIIDLIDNYAN 891
H +++ + +Y N
Sbjct: 709 HTSVVCYLLDYPN 721
Score = 46.0 bits (104), Expect = 6e-04
Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 7/129 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G TAL A +G + + LL+ G+++ + L A+ GH + L+ GAN+
Sbjct: 597 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANV 656
Query: 552 NQKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N+ + +T L LA GHL V+ ++ ++ + G+T L A+K G+
Sbjct: 657 NRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRL------KDGSTMLIEAAKGGHT 710
Query: 611 GIARLLIEH 619
+ L+++
Sbjct: 711 SVVCYLLDY 719
>BC007747-1|AAH07747.2| 830|Homo sapiens ANKRD17 protein protein.
Length = 830
Score = 81.0 bits (191), Expect = 2e-14
Identities = 93/398 (23%), Positives = 164/398 (41%), Gaps = 20/398 (5%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L A+ G IV+ LL +++NA +AL YA + G+ +V+ +LL SGA+I
Sbjct: 122 ITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIE 181
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +G IN + +NE + L LA G+ +
Sbjct: 182 DHNENGHTPLMEAGSAGHVEVARLLL----ENGAGINTH-SNEFKESALTLACYKGHLEM 236
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPNLFEYIHITSSEVKKISC 669
R L+E G++ + TA A ++ + ++L + S + +C
Sbjct: 237 VRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 296
Query: 670 ESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI 729
+ L + ND T ++ A G ++ + A I
Sbjct: 297 GGHVELAALLIERGASLEEVNDEGYT--------PLMEAAREGHEEMVALLLG--QGANI 346
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
E++ L C + ++ + T L AA+ G E L+
Sbjct: 347 NAQTEETQETALTLACCGGFLEVADFLIKAGADI-ELGCSTPLMEAAQEGHLELVKYLLA 405
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
ANV+ T L A N T V +LL GA++ TPL A+ G++
Sbjct: 406 AGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCT 465
Query: 850 AKILLSYNPDITLLNA-TEKTALAVAKDKVHLTIIDLI 886
+ L+S ++ A + T L++A HL +++L+
Sbjct: 466 VQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELL 503
Score = 68.5 bits (160), Expect = 1e-10
Identities = 43/131 (32%), Positives = 69/131 (52%), Gaps = 5/131 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A+ G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++
Sbjct: 386 TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 445
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A GH+ V+ +I G +N AN + +T L LA G+ +
Sbjct: 446 ESEGGRTPLMKAARAGHVCTVQFLI----SKGANVNRTTAN-NDHTVLSLACAGGHLAVV 500
Query: 614 RLLIEHGSEPS 624
LL+ HG++P+
Sbjct: 501 ELLLAHGADPT 511
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/142 (31%), Positives = 69/142 (48%), Gaps = 7/142 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++ S G TAL A G +V+ LLE G+ I + N + L A S GH V +L
Sbjct: 147 VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLL 206
Query: 545 LHSGANIN-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L +GA IN N K + L LA GHL V+ ++ K + +T L
Sbjct: 207 LENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHK------TDEMHTALME 260
Query: 604 ASKWGYEGIARLLIEHGSEPSL 625
A G+ +ARLL++ G++ ++
Sbjct: 261 ACMDGHVEVARLLLDSGAQVNM 282
Score = 55.6 bits (128), Expect = 7e-07
Identities = 98/404 (24%), Positives = 161/404 (39%), Gaps = 34/404 (8%)
Query: 504 KATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLH 563
+A T + S NA + S L A S G N + LL G ++N+ + + L
Sbjct: 34 EAAAALTRMRAESTANAGQSDNRS-LAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLC 92
Query: 564 LAVNNGHLHCVKAIIYFAEHSGRKININCANESGN-TPLHLASKWGYEGIARLLIEHGSE 622
LA + G+ + ++ A H+ N+ G+ TPL A+ G+ I +LL+ H ++
Sbjct: 93 LACSAGYYELAQVLL--AMHA----NVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKAD 146
Query: 623 PSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNL 682
+ Q+S TA YA C + + + I +E + ++
Sbjct: 147 VNAQSSTGNTALTYA-----------CAGGYVDVVKVLLESGASIEDHNENGHTPLME-- 193
Query: 683 TLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI----APDKEKSNS 738
A +EN I + LAC+ +++ F+ A + K++
Sbjct: 194 AGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDE 253
Query: 739 LCHPLCE-CQYCKRKTESC---TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANV 794
+ L E C + + VN+ + + L AA G E +LI A++
Sbjct: 254 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASL 313
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA-IDVARNTPLHDASETGNIGAAKIL 853
N + TPL AA ++ LLL GANINA + + T L A G + A L
Sbjct: 314 EEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFL 373
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANKYANT 896
+ DI L T L A + HL ++ L+ AN +A T
Sbjct: 374 IKAGADIEL---GCSTPLMEAAQEGHLELVKYLLAAGANVHATT 414
Score = 50.0 bits (114), Expect = 4e-05
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ + G TAL YA G + ++L+ A++ ++ +TPL AA ++
Sbjct: 409 NVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQF 468
Query: 820 LLDNGANINAIDVAR-NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
L+ GAN+N +T L A G++ ++LL++ D T T L A
Sbjct: 469 LISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGG 528
Query: 879 HLTIIDLIDNYAN 891
H +++ + +Y N
Sbjct: 529 HTSVVCYLLDYPN 541
Score = 46.0 bits (104), Expect = 6e-04
Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 7/129 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G TAL A +G + + LL+ G+++ + L A+ GH + L+ GAN+
Sbjct: 417 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANV 476
Query: 552 NQKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N+ + +T L LA GHL V+ ++ ++ + G+T L A+K G+
Sbjct: 477 NRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRL------KDGSTMLIEAAKGGHT 530
Query: 611 GIARLLIEH 619
+ L+++
Sbjct: 531 SVVCYLLDY 539
>AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6
protein.
Length = 692
Score = 81.0 bits (191), Expect = 2e-14
Identities = 48/157 (30%), Positives = 83/157 (52%), Gaps = 6/157 (3%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
HG T LH+A+ G +V+ LL+ G +++ D + +ALH A+ G+ ++ L+H G
Sbjct: 41 HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA 100
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+++++ D NT LH A +G K +I +G N+ N++GNT LHLA + +
Sbjct: 101 LDRQDKDGNTALHEASWHGFSQSAKLLI----KAG--ANVLAKNKAGNTALHLACQNSHS 154
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
R+L+ GS L+N+ T A L +++
Sbjct: 155 QSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIR 191
Score = 74.9 bits (176), Expect = 1e-12
Identities = 49/160 (30%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D TALH A++ G I+ L+ G ++ D + +ALH AS G +L+ +
Sbjct: 71 QDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKA 130
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GAN+ KN NT LHLA N H + ++ + K N +G+T LH+A+++
Sbjct: 131 GANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLK------NNAGDTCLHVAARY 184
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ I RLL+ +N TA A L +V K
Sbjct: 185 NHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAK 224
Score = 74.1 bits (174), Expect = 2e-12
Identities = 44/154 (28%), Positives = 84/154 (54%), Gaps = 8/154 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G TALH AS HG + + L++ G+ + A + +ALH A H +LL +
Sbjct: 104 QDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLA 163
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+ + KN +T LH+A HL ++ ++ +++ N++G+T LH+A+
Sbjct: 164 GSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAF------CSVHEKNQAGDTALHVAAAL 217
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYA--HN 639
++ +A++L+E G++ ++ N+ +T + A HN
Sbjct: 218 NHKKVAKILLEAGADTTIVNNAGQTPLETARYHN 251
Score = 60.1 bits (139), Expect = 3e-08
Identities = 39/122 (31%), Positives = 62/122 (50%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D +G TALH A+ +G + +LI ANV +NK T LHLA N+ + R+LL G
Sbjct: 105 DKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAG 164
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
+ + + A +T LH A+ ++ ++LL+ + N TAL VA H +
Sbjct: 165 SRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAK 224
Query: 885 LI 886
++
Sbjct: 225 IL 226
Score = 59.3 bits (137), Expect = 6e-08
Identities = 42/127 (33%), Positives = 62/127 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D++V D TALH A G E LI ++ ++K T LH A+ + + +L
Sbjct: 67 DLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKL 126
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ GAN+ A + A NT LH A + + + ++LL L N T L VA H
Sbjct: 127 LIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNH 186
Query: 880 LTIIDLI 886
L+II L+
Sbjct: 187 LSIIRLL 193
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/108 (32%), Positives = 55/108 (50%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G TALH A + + +L+ + + +N T LH+AA N +IRLLL ++
Sbjct: 141 GNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 200
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
+ + A +T LH A+ + AKILL D T++N +T L A+
Sbjct: 201 HEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETAR 248
Score = 54.4 bits (125), Expect = 2e-06
Identities = 35/113 (30%), Positives = 54/113 (47%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
+G T LH AA G IL+ +++ ++ QT LH A + T +I L+ G
Sbjct: 41 HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA 100
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
++ D NT LH+AS G +AK+L+ ++ N TAL +A H
Sbjct: 101 LDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSH 153
Score = 51.2 bits (117), Expect = 2e-05
Identities = 34/108 (31%), Positives = 50/108 (46%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G T LH AARY +L+ +V+ +N+ T LH+AA N V ++LL+ GA+
Sbjct: 174 GDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADT 233
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
++ A TPL A N A +L T + AVA+
Sbjct: 234 TIVNNAGQTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVAR 281
Score = 48.8 bits (111), Expect = 8e-05
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 6/130 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+++ G TALH+A + + LL GS + + + LH A+ H +++ +LL
Sbjct: 136 AKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLT 195
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+ ++++KN +T LH+A H K ++ +G I N +G TPL A
Sbjct: 196 AFCSVHEKNQAGDTALHVAAALNHKKVAKILL----EAGADTTI--VNNAGQTPLETARY 249
Query: 607 WGYEGIARLL 616
+A LL
Sbjct: 250 HNNPEVALLL 259
Score = 38.7 bits (86), Expect = 0.091
Identities = 19/48 (39%), Positives = 27/48 (56%)
Query: 799 KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
K +TPLHLAA V+++LL G +++ D T LH A+ GN
Sbjct: 40 KHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGN 87
>AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6
protein.
Length = 692
Score = 81.0 bits (191), Expect = 2e-14
Identities = 48/157 (30%), Positives = 83/157 (52%), Gaps = 6/157 (3%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
HG T LH+A+ G +V+ LL+ G +++ D + +ALH A+ G+ ++ L+H G
Sbjct: 41 HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA 100
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+++++ D NT LH A +G K +I +G N+ N++GNT LHLA + +
Sbjct: 101 LDRQDKDGNTALHEASWHGFSQSAKLLI----KAG--ANVLAKNKAGNTALHLACQNSHS 154
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
R+L+ GS L+N+ T A L +++
Sbjct: 155 QSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIR 191
Score = 74.9 bits (176), Expect = 1e-12
Identities = 49/160 (30%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D TALH A++ G I+ L+ G ++ D + +ALH AS G +L+ +
Sbjct: 71 QDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKA 130
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GAN+ KN NT LHLA N H + ++ + K N +G+T LH+A+++
Sbjct: 131 GANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLK------NNAGDTCLHVAARY 184
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ I RLL+ +N TA A L +V K
Sbjct: 185 NHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAK 224
Score = 74.1 bits (174), Expect = 2e-12
Identities = 44/154 (28%), Positives = 84/154 (54%), Gaps = 8/154 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G TALH AS HG + + L++ G+ + A + +ALH A H +LL +
Sbjct: 104 QDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLA 163
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+ + KN +T LH+A HL ++ ++ +++ N++G+T LH+A+
Sbjct: 164 GSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAF------CSVHEKNQAGDTALHVAAAL 217
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYA--HN 639
++ +A++L+E G++ ++ N+ +T + A HN
Sbjct: 218 NHKKVAKILLEAGADTTIVNNAGQTPLETARYHN 251
Score = 60.1 bits (139), Expect = 3e-08
Identities = 39/122 (31%), Positives = 62/122 (50%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D +G TALH A+ +G + +LI ANV +NK T LHLA N+ + R+LL G
Sbjct: 105 DKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAG 164
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
+ + + A +T LH A+ ++ ++LL+ + N TAL VA H +
Sbjct: 165 SRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAK 224
Query: 885 LI 886
++
Sbjct: 225 IL 226
Score = 59.3 bits (137), Expect = 6e-08
Identities = 42/127 (33%), Positives = 62/127 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D++V D TALH A G E LI ++ ++K T LH A+ + + +L
Sbjct: 67 DLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKL 126
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ GAN+ A + A NT LH A + + + ++LL L N T L VA H
Sbjct: 127 LIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNH 186
Query: 880 LTIIDLI 886
L+II L+
Sbjct: 187 LSIIRLL 193
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/108 (32%), Positives = 55/108 (50%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G TALH A + + +L+ + + +N T LH+AA N +IRLLL ++
Sbjct: 141 GNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 200
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
+ + A +T LH A+ + AKILL D T++N +T L A+
Sbjct: 201 HEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETAR 248
Score = 54.4 bits (125), Expect = 2e-06
Identities = 35/113 (30%), Positives = 54/113 (47%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
+G T LH AA G IL+ +++ ++ QT LH A + T +I L+ G
Sbjct: 41 HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA 100
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
++ D NT LH+AS G +AK+L+ ++ N TAL +A H
Sbjct: 101 LDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSH 153
Score = 51.2 bits (117), Expect = 2e-05
Identities = 34/108 (31%), Positives = 50/108 (46%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G T LH AARY +L+ +V+ +N+ T LH+AA N V ++LL+ GA+
Sbjct: 174 GDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADT 233
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
++ A TPL A N A +L T + AVA+
Sbjct: 234 TIVNNAGQTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVAR 281
Score = 48.8 bits (111), Expect = 8e-05
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 6/130 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+++ G TALH+A + + LL GS + + + LH A+ H +++ +LL
Sbjct: 136 AKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLT 195
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+ ++++KN +T LH+A H K ++ +G I N +G TPL A
Sbjct: 196 AFCSVHEKNQAGDTALHVAAALNHKKVAKILL----EAGADTTI--VNNAGQTPLETARY 249
Query: 607 WGYEGIARLL 616
+A LL
Sbjct: 250 HNNPEVALLL 259
Score = 38.7 bits (86), Expect = 0.091
Identities = 19/48 (39%), Positives = 27/48 (56%)
Query: 799 KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
K +TPLHLAA V+++LL G +++ D T LH A+ GN
Sbjct: 40 KHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGN 87
>AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1
variant protein.
Length = 931
Score = 81.0 bits (191), Expect = 2e-14
Identities = 84/336 (25%), Positives = 146/336 (43%), Gaps = 19/336 (5%)
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
T LH+A +G V+ ++ G ++ ++ TPLH++++ G I + L++
Sbjct: 12 TALHMAARSGQAEVVRYLV----QDGAQVEAKAKDDQ--TPLHISARLGKADIVQQLLQQ 65
Query: 620 GSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEY---IHITSSEVKKISCESEKPTS 676
G+ P N+ + + H L + + L ++ + IT+ + + K
Sbjct: 66 GASP---NAATTSGYTPLH-LSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 121
Query: 677 LKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKS 736
L++ NL L+ S + DA+ + + A Y + K+A ++ S A K
Sbjct: 122 LEVANLLLQKSASPDAA----GKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAA-KNGY 176
Query: 737 NSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC 796
L + Q T D N G ++H AA+ G + ++L+ ANVN
Sbjct: 177 TPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNL 236
Query: 797 RNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSY 856
NK TPLHLAA ++ V +L++ GA+++A TPLH GNI LL +
Sbjct: 237 SNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQH 296
Query: 857 NPDITLLNATEKTALAVAKDKVHLTIID-LIDNYAN 891
+ + T L A + H II+ L+ N A+
Sbjct: 297 SAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNAS 332
Score = 77.0 bits (181), Expect = 3e-13
Identities = 47/168 (27%), Positives = 84/168 (50%), Gaps = 13/168 (7%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
+G T LH+A+ + I TLLE G++ NA +++H A+ GH +++ +LL AN
Sbjct: 174 NGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNAN 233
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N N TPLHLA ++ + ++ H ++ + G TPLH+ +G
Sbjct: 234 VNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAH------VDAQTKMGYTPLHVGCHYGNI 287
Query: 611 GIARLLIEHGSE--PSLQNSY---HKTAFD-YAHNLRILQVLKSCTPN 652
I L++H ++ +N Y H+ A + H + +L + + +PN
Sbjct: 288 KIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL-LQNNASPN 334
Score = 76.6 bits (180), Expect = 4e-13
Identities = 43/140 (30%), Positives = 75/140 (53%), Gaps = 6/140 (4%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ G TALH+A+ G+A +V L++ G+++ A ++ + LH ++ G +++
Sbjct: 2 TLAHVPQRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 61
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GA+ N TPLHL+ GH + + F G ++I + G TPLH+
Sbjct: 62 LLQQGASPNAATTSGYTPLHLSAREGH----EDVAAFLLDHGASLSI--TTKKGFTPLHV 115
Query: 604 ASKWGYEGIARLLIEHGSEP 623
A+K+G +A LL++ + P
Sbjct: 116 AAKYGKLEVANLLLQKSASP 135
Score = 70.5 bits (165), Expect = 2e-11
Identities = 36/127 (28%), Positives = 63/127 (49%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ + +G T LH AA+ +L+ A+V+ + K TPLH+ ++
Sbjct: 233 NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNF 292
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL + A +NA TPLH A++ G+ +LL N L TAL +A+ +
Sbjct: 293 LLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGY 352
Query: 880 LTIIDLI 886
++++D +
Sbjct: 353 ISVVDTL 359
Score = 68.5 bits (160), Expect = 1e-10
Identities = 41/119 (34%), Positives = 61/119 (51%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G TALH AAR G E L+ + A V + K QTPLH++A K +++ LL GA+
Sbjct: 10 GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 69
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
NA + TPLH ++ G+ A LL + +++ T L VA L + +L+
Sbjct: 70 NAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 128
Score = 62.9 bits (146), Expect = 5e-09
Identities = 33/99 (33%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 527 SALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGR 586
+ALH A+ G V+ L+ GA + K D TPLH++ G V+ ++ +
Sbjct: 12 TALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQ------Q 65
Query: 587 KININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSL 625
+ N A SG TPLHL+++ G+E +A L++HG+ S+
Sbjct: 66 GASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSI 104
Score = 60.5 bits (140), Expect = 3e-08
Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 6/136 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHVA+ +GK + LL+ + +A + + LH A+ +Q V L+LL GA+
Sbjct: 109 GFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASP 168
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ + TPLH+A + ++ + + N G +HLA++ G+
Sbjct: 169 HAAAKNGYTPLHIAAKKNQMDIATTLLEYG------ADANAVTRQGIASVHLAAQEGHVD 222
Query: 612 IARLLIEHGSEPSLQN 627
+ LL+ + +L N
Sbjct: 223 MVSLLLGRNANVNLSN 238
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/93 (31%), Positives = 51/93 (54%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LHV +G IV LL+ +++NA N + LH A+ +GH +++ +LL + A+
Sbjct: 274 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASP 333
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHS 584
N+ ++ NT L +A G++ V + E +
Sbjct: 334 NELTVNGNTALGIARRLGYISVVDTLKIVTEET 366
Score = 57.2 bits (132), Expect = 2e-07
Identities = 60/301 (19%), Positives = 121/301 (40%), Gaps = 12/301 (3%)
Query: 595 ESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLF 654
+ G T LH+A++ G + R L++ G++ + +T + L +++
Sbjct: 8 QRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 67
Query: 655 EYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDV 714
T+S + + + +++ D + AS +I K + A YG +
Sbjct: 68 SPNAATTSGYTPLHLSAREGH----EDVAAFLLD-HGASLSITTKKGFTPLHVAAKYGKL 122
Query: 715 KLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCT---DFDVNVCDSNGFTA 771
++A N+ +PD + L Y +K + NG+T
Sbjct: 123 EVA----NLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTP 178
Query: 772 LHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID 831
LH AA+ + L+ A+ N ++ +HLAA ++ LLL AN+N +
Sbjct: 179 LHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSN 238
Query: 832 VARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYAN 891
+ TPLH A++ + A++L++ + T L V ++ I++ + ++
Sbjct: 239 KSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 298
Query: 892 K 892
K
Sbjct: 299 K 299
Score = 56.0 bits (129), Expect = 6e-07
Identities = 39/127 (30%), Positives = 61/127 (48%), Gaps = 3/127 (2%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T LH +AR G + L+ A+ N TPLHL+A V LLD+GA+++
Sbjct: 45 TPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSI 104
Query: 830 IDVARNTPLHDASETGNIGAAKILL--SYNPDITLLNATEKTALAVAKDKVHLTIIDLID 887
TPLH A++ G + A +LL S +PD + +A D + ++ L+D
Sbjct: 105 TTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALL-LLD 163
Query: 888 NYANKYA 894
A+ +A
Sbjct: 164 QGASPHA 170
Score = 56.0 bits (129), Expect = 6e-07
Identities = 37/131 (28%), Positives = 63/131 (48%), Gaps = 6/131 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+++ G + LL+ G+ ++ T + LH A+ G V +LL A+
Sbjct: 76 GYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASP 135
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ TPLH+A H K + + + + A ++G TPLH+A+K
Sbjct: 136 DAAGKSGLTPLHVA---AHYDNQKVALLLLDQGA---SPHAAAKNGYTPLHIAAKKNQMD 189
Query: 612 IARLLIEHGSE 622
IA L+E+G++
Sbjct: 190 IATTLLEYGAD 200
>BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1
(Drosophila) protein.
Length = 1006
Score = 80.6 bits (190), Expect = 2e-14
Identities = 48/147 (32%), Positives = 82/147 (55%), Gaps = 8/147 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG-AN 550
G TA+ AS +G I++ LL+ ++ A D + A+H+A+ G + ++ +LH G A+
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAF-GDEGAVIEVLHRGSAD 522
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N +N + TPLH+AVN GHL VK ++ F H + + G+TPLH A +
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHP------SLQDSEGDTPLHDAISKKRD 576
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYA 637
I +L+E G++ ++ N+ A +A
Sbjct: 577 DILAVLLEAGADVTITNNNGFNALHHA 603
Score = 67.7 bits (158), Expect = 2e-10
Identities = 43/114 (37%), Positives = 61/114 (53%), Gaps = 4/114 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNR--ANVNCRNKKAQTPLHLAAINNKTVVI 817
DV D +G A+H+AA +G DE I + +R A++N RNK+ QTPLH+A V+
Sbjct: 489 DVEAEDKDGDRAVHHAA-FG-DEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVV 546
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
+ LLD G + + D +TPLHDA +LL D+T+ N AL
Sbjct: 547 KTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNAL 600
Score = 61.7 bits (143), Expect = 1e-08
Identities = 43/164 (26%), Positives = 79/164 (48%), Gaps = 4/164 (2%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +R+ T LH+A G +V+TLL+ G + D + LH A S+ ++L +L
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L +GA++ N + LH A G+ ++ ++ R ++ + G T LHLA
Sbjct: 583 LEAGADVTITNNNGFNALHHAALRGNPSAMRVLL---SKLPRPWIVDEKKDDGYTALHLA 639
Query: 605 SKWGYEGIARLLIEHG-SEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ + +A LL+ G + +QN +TA A + Q+++
Sbjct: 640 ALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVR 683
Score = 58.4 bits (135), Expect = 1e-07
Identities = 41/165 (24%), Positives = 84/165 (50%), Gaps = 11/165 (6%)
Query: 492 GLTALHVASIHGKATIVETLLEMGS-EINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
G TALH+A+++ + E L+ G+ ++ ++N+ +ALH A R H ++ +L+ +GA
Sbjct: 632 GYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAK 691
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL------A 604
++ ++ D +TPLH A+ + L ++ + + G+ ++ A E L + A
Sbjct: 692 LDIQDKDGDTPLHEALRHHTLSQLRQ-LQDMQDVGK---VDAAWEPSKNTLIMGLGTQGA 747
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSC 649
K IA L +G++ S++N ++ D + + + L C
Sbjct: 748 EKKSAASIACFLAANGADLSIRNKKGQSPLDLCPDPNLCKALAKC 792
Score = 55.6 bits (128), Expect = 7e-07
Identities = 30/76 (39%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Query: 767 NGFTALHYAARYGLDEFCNILIFN-RANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGA 825
+G+TALH AA E +L+ AN++ +N QT LHLA T ++RLL+ GA
Sbjct: 631 DGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGA 690
Query: 826 NINAIDVARNTPLHDA 841
++ D +TPLH+A
Sbjct: 691 KLDIQDKDGDTPLHEA 706
Score = 53.2 bits (122), Expect = 4e-06
Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 1/120 (0%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D DVN G TA+ A++ G + +L+ +V +K +H AA ++ VI
Sbjct: 455 DVDVNG-QCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVI 513
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
+L A++NA + R TPLH A G++ K LL + +L ++ T L A K
Sbjct: 514 EVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISK 573
Score = 50.8 bits (116), Expect = 2e-05
Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 6/137 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+ D G A+H A+ + ++E L +++NA + + LH A ++GH V+ LL
Sbjct: 492 AEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLD 551
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
G + + ++ + +TPLH A++ + ++ +G + I N +G LH A+
Sbjct: 552 FGCHPSLQDSEGDTPLHDAISKKRDDILAVLL----EAGADVTI--TNNNGFNALHHAAL 605
Query: 607 WGYEGIARLLIEHGSEP 623
G R+L+ P
Sbjct: 606 RGNPSAMRVLLSKLPRP 622
Score = 47.2 bits (107), Expect = 3e-04
Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 3/135 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + T LH A G + L+ + + ++ + TPLH A + ++ +
Sbjct: 522 DLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAV 581
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK---TALAVAKD 876
LL+ GA++ + LH A+ GN A ++LLS P +++ + TAL +A
Sbjct: 582 LLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAAL 641
Query: 877 KVHLTIIDLIDNYAN 891
H+ + +L+ + N
Sbjct: 642 NNHVEVAELLVHQGN 656
Score = 35.5 bits (78), Expect = 0.84
Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
Query: 788 IFNRANVNCRNKKA-QTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
+ R +V+ + A T + A+ N +++LLL ++ A D + +H A+ G+
Sbjct: 450 LLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAA-FGD 508
Query: 847 IGAA-KILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
GA ++L + D+ N +T L +A +K HL ++
Sbjct: 509 EGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVV 546
>BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1
(Drosophila) protein.
Length = 1006
Score = 80.6 bits (190), Expect = 2e-14
Identities = 48/147 (32%), Positives = 82/147 (55%), Gaps = 8/147 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG-AN 550
G TA+ AS +G I++ LL+ ++ A D + A+H+A+ G + ++ +LH G A+
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAF-GDEGAVIEVLHRGSAD 522
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N +N + TPLH+AVN GHL VK ++ F H + + G+TPLH A +
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHP------SLQDSEGDTPLHDAISKKRD 576
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYA 637
I +L+E G++ ++ N+ A +A
Sbjct: 577 DILAVLLEAGADVTITNNNGFNALHHA 603
Score = 67.7 bits (158), Expect = 2e-10
Identities = 43/114 (37%), Positives = 61/114 (53%), Gaps = 4/114 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNR--ANVNCRNKKAQTPLHLAAINNKTVVI 817
DV D +G A+H+AA +G DE I + +R A++N RNK+ QTPLH+A V+
Sbjct: 489 DVEAEDKDGDRAVHHAA-FG-DEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVV 546
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
+ LLD G + + D +TPLHDA +LL D+T+ N AL
Sbjct: 547 KTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNAL 600
Score = 61.7 bits (143), Expect = 1e-08
Identities = 43/164 (26%), Positives = 79/164 (48%), Gaps = 4/164 (2%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +R+ T LH+A G +V+TLL+ G + D + LH A S+ ++L +L
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L +GA++ N + LH A G+ ++ ++ R ++ + G T LHLA
Sbjct: 583 LEAGADVTITNNNGFNALHHAALRGNPSAMRVLL---SKLPRPWIVDEKKDDGYTALHLA 639
Query: 605 SKWGYEGIARLLIEHG-SEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ + +A LL+ G + +QN +TA A + Q+++
Sbjct: 640 ALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVR 683
Score = 58.4 bits (135), Expect = 1e-07
Identities = 41/165 (24%), Positives = 84/165 (50%), Gaps = 11/165 (6%)
Query: 492 GLTALHVASIHGKATIVETLLEMGS-EINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
G TALH+A+++ + E L+ G+ ++ ++N+ +ALH A R H ++ +L+ +GA
Sbjct: 632 GYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAK 691
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL------A 604
++ ++ D +TPLH A+ + L ++ + + G+ ++ A E L + A
Sbjct: 692 LDIQDKDGDTPLHEALRHHTLSQLRQ-LQDMQDVGK---VDAAWEPSKNTLIMGLGTQGA 747
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSC 649
K IA L +G++ S++N ++ D + + + L C
Sbjct: 748 EKKSAASIACFLAANGADLSIRNKKGQSPLDLCPDPNLCKALAKC 792
Score = 55.6 bits (128), Expect = 7e-07
Identities = 30/76 (39%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Query: 767 NGFTALHYAARYGLDEFCNILIFN-RANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGA 825
+G+TALH AA E +L+ AN++ +N QT LHLA T ++RLL+ GA
Sbjct: 631 DGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGA 690
Query: 826 NINAIDVARNTPLHDA 841
++ D +TPLH+A
Sbjct: 691 KLDIQDKDGDTPLHEA 706
Score = 53.2 bits (122), Expect = 4e-06
Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 1/120 (0%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D DVN G TA+ A++ G + +L+ +V +K +H AA ++ VI
Sbjct: 455 DVDVNG-QCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVI 513
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
+L A++NA + R TPLH A G++ K LL + +L ++ T L A K
Sbjct: 514 EVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISK 573
Score = 50.8 bits (116), Expect = 2e-05
Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 6/137 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+ D G A+H A+ + ++E L +++NA + + LH A ++GH V+ LL
Sbjct: 492 AEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLD 551
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
G + + ++ + +TPLH A++ + ++ +G + I N +G LH A+
Sbjct: 552 FGCHPSLQDSEGDTPLHDAISKKRDDILAVLL----EAGADVTI--TNNNGFNALHHAAL 605
Query: 607 WGYEGIARLLIEHGSEP 623
G R+L+ P
Sbjct: 606 RGNPSAMRVLLSKLPRP 622
Score = 47.2 bits (107), Expect = 3e-04
Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 3/135 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + T LH A G + L+ + + ++ + TPLH A + ++ +
Sbjct: 522 DLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAV 581
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK---TALAVAKD 876
LL+ GA++ + LH A+ GN A ++LLS P +++ + TAL +A
Sbjct: 582 LLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAAL 641
Query: 877 KVHLTIIDLIDNYAN 891
H+ + +L+ + N
Sbjct: 642 NNHVEVAELLVHQGN 656
Score = 35.5 bits (78), Expect = 0.84
Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
Query: 788 IFNRANVNCRNKKA-QTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
+ R +V+ + A T + A+ N +++LLL ++ A D + +H A+ G+
Sbjct: 450 LLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAA-FGD 508
Query: 847 IGAA-KILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
GA ++L + D+ N +T L +A +K HL ++
Sbjct: 509 EGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVV 546
>BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6
protein.
Length = 722
Score = 80.6 bits (190), Expect = 2e-14
Identities = 47/157 (29%), Positives = 83/157 (52%), Gaps = 6/157 (3%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
HG T LH+A+ G +V+ LL+ G +++ D + +ALH A+ G+ ++ L+H G
Sbjct: 41 HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA 100
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+++++ D NT LH A +G K ++ +G N+ N++GNT LHLA + +
Sbjct: 101 LDRQDKDGNTALHEASWHGFSQSAKLLV----KAG--ANVLAKNKAGNTALHLACQNSHS 154
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
R+L+ GS L+N+ T A L +++
Sbjct: 155 QSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIR 191
Score = 76.6 bits (180), Expect = 4e-13
Identities = 49/188 (26%), Positives = 97/188 (51%), Gaps = 8/188 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G TALH AS HG + + L++ G+ + A + +ALH A H +LL +
Sbjct: 104 QDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLA 163
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+ + KN +T LH+A HL ++ ++ +++ N++G+T LH+A+
Sbjct: 164 GSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAF------CSVHEKNQAGDTALHVAAAL 217
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYA--HNLRILQVLKSCTPNLFEYIHITSSEVK 665
++ +A++L+E G++ ++ N+ +T + A HN + +L + P + + S K
Sbjct: 218 NHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKK 277
Query: 666 KISCESEK 673
+ + E+
Sbjct: 278 RERLKEER 285
Score = 74.5 bits (175), Expect = 1e-12
Identities = 49/160 (30%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D TALH A++ G I+ L+ G ++ D + +ALH AS G +L+ +
Sbjct: 71 QDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKA 130
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GAN+ KN NT LHLA N H + ++ + K N +G+T LH+A+++
Sbjct: 131 GANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLK------NNAGDTCLHVAARY 184
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ I RLL+ +N TA A L +V K
Sbjct: 185 NHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAK 224
Score = 59.7 bits (138), Expect = 5e-08
Identities = 38/122 (31%), Positives = 62/122 (50%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D +G TALH A+ +G + +L+ ANV +NK T LHLA N+ + R+LL G
Sbjct: 105 DKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAG 164
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
+ + + A +T LH A+ ++ ++LL+ + N TAL VA H +
Sbjct: 165 SRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAK 224
Query: 885 LI 886
++
Sbjct: 225 IL 226
Score = 58.8 bits (136), Expect = 8e-08
Identities = 42/127 (33%), Positives = 62/127 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D++V D TALH A G E LI ++ ++K T LH A+ + + +L
Sbjct: 67 DLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKL 126
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ GAN+ A + A NT LH A + + + ++LL L N T L VA H
Sbjct: 127 LVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNH 186
Query: 880 LTIIDLI 886
L+II L+
Sbjct: 187 LSIIRLL 193
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/108 (32%), Positives = 55/108 (50%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G TALH A + + +L+ + + +N T LH+AA N +IRLLL ++
Sbjct: 141 GNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 200
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
+ + A +T LH A+ + AKILL D T++N +T L A+
Sbjct: 201 HEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETAR 248
Score = 54.0 bits (124), Expect = 2e-06
Identities = 35/113 (30%), Positives = 54/113 (47%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
+G T LH AA G IL+ +++ ++ QT LH A + T +I L+ G
Sbjct: 41 HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA 100
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
++ D NT LH+AS G +AK+L+ ++ N TAL +A H
Sbjct: 101 LDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSH 153
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G T LH AARY +L+ +V+ +N+ T LH+AA N V ++LL+ GA+
Sbjct: 174 GDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADT 233
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++ A TPL A N A +LL+ P +
Sbjct: 234 TIVNNAGQTPLETARYHNNPEVA-LLLTKAPQV 265
Score = 48.8 bits (111), Expect = 8e-05
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 6/130 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+++ G TALH+A + + LL GS + + + LH A+ H +++ +LL
Sbjct: 136 AKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLT 195
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+ ++++KN +T LH+A H K ++ +G I N +G TPL A
Sbjct: 196 AFCSVHEKNQAGDTALHVAAALNHKKVAKILL----EAGADTTI--VNNAGQTPLETARY 249
Query: 607 WGYEGIARLL 616
+A LL
Sbjct: 250 HNNPEVALLL 259
Score = 38.7 bits (86), Expect = 0.091
Identities = 19/48 (39%), Positives = 27/48 (56%)
Query: 799 KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
K +TPLHLAA V+++LL G +++ D T LH A+ GN
Sbjct: 40 KHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGN 87
>AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein.
Length = 1006
Score = 80.6 bits (190), Expect = 2e-14
Identities = 48/147 (32%), Positives = 82/147 (55%), Gaps = 8/147 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG-AN 550
G TA+ AS +G I++ LL+ ++ A D + A+H+A+ G + ++ +LH G A+
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAF-GDEGAVIEVLHRGSAD 522
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N +N + TPLH+AVN GHL VK ++ F H + + G+TPLH A +
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHP------SLQDSEGDTPLHDAISKKRD 576
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYA 637
I +L+E G++ ++ N+ A +A
Sbjct: 577 DILAVLLEAGADVTITNNNGFNALHHA 603
Score = 67.7 bits (158), Expect = 2e-10
Identities = 43/114 (37%), Positives = 61/114 (53%), Gaps = 4/114 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNR--ANVNCRNKKAQTPLHLAAINNKTVVI 817
DV D +G A+H+AA +G DE I + +R A++N RNK+ QTPLH+A V+
Sbjct: 489 DVEAEDKDGDRAVHHAA-FG-DEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVV 546
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
+ LLD G + + D +TPLHDA +LL D+T+ N AL
Sbjct: 547 KTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNAL 600
Score = 61.7 bits (143), Expect = 1e-08
Identities = 43/164 (26%), Positives = 79/164 (48%), Gaps = 4/164 (2%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +R+ T LH+A G +V+TLL+ G + D + LH A S+ ++L +L
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L +GA++ N + LH A G+ ++ ++ R ++ + G T LHLA
Sbjct: 583 LEAGADVTITNNNGFNALHHAALRGNPSAMRVLL---SKLPRPWIVDEKKDDGYTALHLA 639
Query: 605 SKWGYEGIARLLIEHG-SEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ + +A LL+ G + +QN +TA A + Q+++
Sbjct: 640 ALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVR 683
Score = 58.4 bits (135), Expect = 1e-07
Identities = 41/165 (24%), Positives = 84/165 (50%), Gaps = 11/165 (6%)
Query: 492 GLTALHVASIHGKATIVETLLEMGS-EINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
G TALH+A+++ + E L+ G+ ++ ++N+ +ALH A R H ++ +L+ +GA
Sbjct: 632 GYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAK 691
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL------A 604
++ ++ D +TPLH A+ + L ++ + + G+ ++ A E L + A
Sbjct: 692 LDIQDKDGDTPLHEALRHHTLSQLRQ-LQDMQDVGK---VDAAWEPSKNTLIMGLGTQGA 747
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSC 649
K IA L +G++ S++N ++ D + + + L C
Sbjct: 748 EKKSAASIACFLAANGADLSIRNKKGQSPLDLCPDPNLCKALAKC 792
Score = 55.6 bits (128), Expect = 7e-07
Identities = 30/76 (39%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Query: 767 NGFTALHYAARYGLDEFCNILIFN-RANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGA 825
+G+TALH AA E +L+ AN++ +N QT LHLA T ++RLL+ GA
Sbjct: 631 DGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGA 690
Query: 826 NINAIDVARNTPLHDA 841
++ D +TPLH+A
Sbjct: 691 KLDIQDKDGDTPLHEA 706
Score = 53.2 bits (122), Expect = 4e-06
Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 1/120 (0%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D DVN G TA+ A++ G + +L+ +V +K +H AA ++ VI
Sbjct: 455 DVDVNG-QCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVI 513
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
+L A++NA + R TPLH A G++ K LL + +L ++ T L A K
Sbjct: 514 EVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISK 573
Score = 50.8 bits (116), Expect = 2e-05
Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 6/137 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+ D G A+H A+ + ++E L +++NA + + LH A ++GH V+ LL
Sbjct: 492 AEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLD 551
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
G + + ++ + +TPLH A++ + ++ +G + I N +G LH A+
Sbjct: 552 FGCHPSLQDSEGDTPLHDAISKKRDDILAVLL----EAGADVTI--TNNNGFNALHHAAL 605
Query: 607 WGYEGIARLLIEHGSEP 623
G R+L+ P
Sbjct: 606 RGNPSAMRVLLSKLPRP 622
Score = 47.2 bits (107), Expect = 3e-04
Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 3/135 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + T LH A G + L+ + + ++ + TPLH A + ++ +
Sbjct: 522 DLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAV 581
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK---TALAVAKD 876
LL+ GA++ + LH A+ GN A ++LLS P +++ + TAL +A
Sbjct: 582 LLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAAL 641
Query: 877 KVHLTIIDLIDNYAN 891
H+ + +L+ + N
Sbjct: 642 NNHVEVAELLVHQGN 656
Score = 35.5 bits (78), Expect = 0.84
Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
Query: 788 IFNRANVNCRNKKA-QTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
+ R +V+ + A T + A+ N +++LLL ++ A D + +H A+ G+
Sbjct: 450 LLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAA-FGD 508
Query: 847 IGAA-KILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
GA ++L + D+ N +T L +A +K HL ++
Sbjct: 509 EGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVV 546
>AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein.
Length = 997
Score = 80.6 bits (190), Expect = 2e-14
Identities = 48/147 (32%), Positives = 82/147 (55%), Gaps = 8/147 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG-AN 550
G TA+ AS +G I++ LL+ ++ A D + A+H+A+ G + ++ +LH G A+
Sbjct: 455 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAF-GDEGAVIEVLHRGSAD 513
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+N +N + TPLH+AVN GHL VK ++ F H + + G+TPLH A +
Sbjct: 514 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHP------SLQDSEGDTPLHDAISKKRD 567
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYA 637
I +L+E G++ ++ N+ A +A
Sbjct: 568 DILAVLLEAGADVTITNNNGFNALHHA 594
Score = 67.7 bits (158), Expect = 2e-10
Identities = 43/114 (37%), Positives = 61/114 (53%), Gaps = 4/114 (3%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNR--ANVNCRNKKAQTPLHLAAINNKTVVI 817
DV D +G A+H+AA +G DE I + +R A++N RNK+ QTPLH+A V+
Sbjct: 480 DVEAEDKDGDRAVHHAA-FG-DEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVV 537
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
+ LLD G + + D +TPLHDA +LL D+T+ N AL
Sbjct: 538 KTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNAL 591
Score = 61.7 bits (143), Expect = 1e-08
Identities = 43/164 (26%), Positives = 79/164 (48%), Gaps = 4/164 (2%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +R+ T LH+A G +V+TLL+ G + D + LH A S+ ++L +L
Sbjct: 514 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 573
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L +GA++ N + LH A G+ ++ ++ R ++ + G T LHLA
Sbjct: 574 LEAGADVTITNNNGFNALHHAALRGNPSAMRVLL---SKLPRPWIVDEKKDDGYTALHLA 630
Query: 605 SKWGYEGIARLLIEHG-SEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ + +A LL+ G + +QN +TA A + Q+++
Sbjct: 631 ALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVR 674
Score = 58.4 bits (135), Expect = 1e-07
Identities = 41/165 (24%), Positives = 84/165 (50%), Gaps = 11/165 (6%)
Query: 492 GLTALHVASIHGKATIVETLLEMGS-EINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
G TALH+A+++ + E L+ G+ ++ ++N+ +ALH A R H ++ +L+ +GA
Sbjct: 623 GYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAK 682
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL------A 604
++ ++ D +TPLH A+ + L ++ + + G+ ++ A E L + A
Sbjct: 683 LDIQDKDGDTPLHEALRHHTLSQLRQ-LQDMQDVGK---VDAAWEPSKNTLIMGLGTQGA 738
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSC 649
K IA L +G++ S++N ++ D + + + L C
Sbjct: 739 EKKSAASIACFLAANGADLSIRNKKGQSPLDLCPDPNLCKALAKC 783
Score = 55.6 bits (128), Expect = 7e-07
Identities = 30/76 (39%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Query: 767 NGFTALHYAARYGLDEFCNILIFN-RANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGA 825
+G+TALH AA E +L+ AN++ +N QT LHLA T ++RLL+ GA
Sbjct: 622 DGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGA 681
Query: 826 NINAIDVARNTPLHDA 841
++ D +TPLH+A
Sbjct: 682 KLDIQDKDGDTPLHEA 697
Score = 53.2 bits (122), Expect = 4e-06
Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 1/120 (0%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D DVN G TA+ A++ G + +L+ +V +K +H AA ++ VI
Sbjct: 446 DVDVNG-QCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVI 504
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
+L A++NA + R TPLH A G++ K LL + +L ++ T L A K
Sbjct: 505 EVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISK 564
Score = 50.8 bits (116), Expect = 2e-05
Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 6/137 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+ D G A+H A+ + ++E L +++NA + + LH A ++GH V+ LL
Sbjct: 483 AEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLD 542
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
G + + ++ + +TPLH A++ + ++ +G + I N +G LH A+
Sbjct: 543 FGCHPSLQDSEGDTPLHDAISKKRDDILAVLL----EAGADVTI--TNNNGFNALHHAAL 596
Query: 607 WGYEGIARLLIEHGSEP 623
G R+L+ P
Sbjct: 597 RGNPSAMRVLLSKLPRP 613
Score = 47.2 bits (107), Expect = 3e-04
Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 3/135 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + T LH A G + L+ + + ++ + TPLH A + ++ +
Sbjct: 513 DLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAV 572
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK---TALAVAKD 876
LL+ GA++ + LH A+ GN A ++LLS P +++ + TAL +A
Sbjct: 573 LLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAAL 632
Query: 877 KVHLTIIDLIDNYAN 891
H+ + +L+ + N
Sbjct: 633 NNHVEVAELLVHQGN 647
Score = 35.5 bits (78), Expect = 0.84
Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
Query: 788 IFNRANVNCRNKKA-QTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
+ R +V+ + A T + A+ N +++LLL ++ A D + +H A+ G+
Sbjct: 441 LLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAA-FGD 499
Query: 847 IGAA-KILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
GA ++L + D+ N +T L +A +K HL ++
Sbjct: 500 EGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVV 537
>AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein.
Length = 693
Score = 80.6 bits (190), Expect = 2e-14
Identities = 47/157 (29%), Positives = 83/157 (52%), Gaps = 6/157 (3%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
HG T LH+A+ G +V+ LL+ G +++ D + +ALH A+ G+ ++ L+H G
Sbjct: 42 HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA 101
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+++++ D NT LH A +G K ++ +G N+ N++GNT LHLA + +
Sbjct: 102 LDRQDKDGNTALHEASWHGFSQSAKLLV----KAG--ANVLAKNKAGNTALHLACQNSHS 155
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
R+L+ GS L+N+ T A L +++
Sbjct: 156 QSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIR 192
Score = 74.5 bits (175), Expect = 1e-12
Identities = 49/160 (30%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D TALH A++ G I+ L+ G ++ D + +ALH AS G +L+ +
Sbjct: 72 QDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKA 131
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GAN+ KN NT LHLA N H + ++ + K N +G+T LH+A+++
Sbjct: 132 GANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLK------NNAGDTCLHVAARY 185
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ I RLL+ +N TA A L +V K
Sbjct: 186 NHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAK 225
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/154 (28%), Positives = 84/154 (54%), Gaps = 8/154 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G TALH AS HG + + L++ G+ + A + +ALH A H +LL +
Sbjct: 105 QDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLA 164
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+ + KN +T LH+A HL ++ ++ +++ N++G+T LH+A+
Sbjct: 165 GSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAF------CSVHEKNQAGDTALHVAAAL 218
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYA--HN 639
++ +A++L+E G++ ++ N+ +T + A HN
Sbjct: 219 NHKKVAKILLEAGADTTIVNNAGQTPLETARYHN 252
Score = 59.7 bits (138), Expect = 5e-08
Identities = 38/122 (31%), Positives = 62/122 (50%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D +G TALH A+ +G + +L+ ANV +NK T LHLA N+ + R+LL G
Sbjct: 106 DKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAG 165
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
+ + + A +T LH A+ ++ ++LL+ + N TAL VA H +
Sbjct: 166 SRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAK 225
Query: 885 LI 886
++
Sbjct: 226 IL 227
Score = 58.8 bits (136), Expect = 8e-08
Identities = 42/127 (33%), Positives = 62/127 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D++V D TALH A G E LI ++ ++K T LH A+ + + +L
Sbjct: 68 DLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKL 127
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ GAN+ A + A NT LH A + + + ++LL L N T L VA H
Sbjct: 128 LVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNH 187
Query: 880 LTIIDLI 886
L+II L+
Sbjct: 188 LSIIRLL 194
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/108 (32%), Positives = 55/108 (50%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G TALH A + + +L+ + + +N T LH+AA N +IRLLL ++
Sbjct: 142 GNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 201
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
+ + A +T LH A+ + AKILL D T++N +T L A+
Sbjct: 202 HEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETAR 249
Score = 54.0 bits (124), Expect = 2e-06
Identities = 35/113 (30%), Positives = 54/113 (47%)
Query: 767 NGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
+G T LH AA G IL+ +++ ++ QT LH A + T +I L+ G
Sbjct: 42 HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA 101
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
++ D NT LH+AS G +AK+L+ ++ N TAL +A H
Sbjct: 102 LDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSH 154
Score = 51.2 bits (117), Expect = 2e-05
Identities = 34/108 (31%), Positives = 50/108 (46%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G T LH AARY +L+ +V+ +N+ T LH+AA N V ++LL+ GA+
Sbjct: 175 GDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADT 234
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
++ A TPL A N A +L T + AVA+
Sbjct: 235 TIVNNAGQTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVAR 282
Score = 48.8 bits (111), Expect = 8e-05
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 6/130 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+++ G TALH+A + + LL GS + + + LH A+ H +++ +LL
Sbjct: 137 AKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLT 196
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+ ++++KN +T LH+A H K ++ +G I N +G TPL A
Sbjct: 197 AFCSVHEKNQAGDTALHVAAALNHKKVAKILL----EAGADTTI--VNNAGQTPLETARY 250
Query: 607 WGYEGIARLL 616
+A LL
Sbjct: 251 HNNPEVALLL 260
Score = 38.7 bits (86), Expect = 0.091
Identities = 19/48 (39%), Positives = 27/48 (56%)
Query: 799 KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
K +TPLHLAA V+++LL G +++ D T LH A+ GN
Sbjct: 41 KHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGN 88
>DQ508934-1|ABF57994.1| 591|Homo sapiens SARP3 protein.
Length = 591
Score = 80.2 bits (189), Expect = 3e-14
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 2/132 (1%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T++D G T LH+A+ HG + ++ +L G + + TD E +HYA+ G L +L
Sbjct: 438 LTAQDDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLL 497
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ G +I + + N P+HLA GHLHC K ++ + S + N++G L LA
Sbjct: 498 VKWGCSIEDVDYNGNLPVHLAAMEGHLHCFKFLV--SRMSSATQVLKAFNDNGENVLDLA 555
Query: 605 SKWGYEGIARLL 616
++ + I + +
Sbjct: 556 QRFFKQNILQFI 567
Score = 67.3 bits (157), Expect = 2e-10
Identities = 40/137 (29%), Positives = 73/137 (53%), Gaps = 9/137 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T+RD TA H+A+I G+ V+ L+ G+ + A D C+ LH A++ GH L ++
Sbjct: 408 VTTRD---WTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIM 464
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L SG + + + + P+H A +G L C++ ++ + +I + +GN P+HLA
Sbjct: 465 LRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWG------CSIEDVDYNGNLPVHLA 518
Query: 605 SKWGYEGIARLLIEHGS 621
+ G+ + L+ S
Sbjct: 519 AMEGHLHCFKFLVSRMS 535
Score = 58.4 bits (135), Expect = 1e-07
Identities = 45/148 (30%), Positives = 71/148 (47%), Gaps = 12/148 (8%)
Query: 496 LHVASIHG--KATIVETLLEM---GSEINATD-LNECSALHYASSRGHQNVLLMLLHSGA 549
+H SIH +A V+ L E+ G+ IN D L++ + LH+A+ G L LL GA
Sbjct: 344 MHFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGA 403
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+I T H+A G CV+A+I N+ ++ G TPLHLA+ G+
Sbjct: 404 DITHVTTRDWTASHIAAIRGQDACVQALIM------NGANLTAQDDRGCTPLHLAATHGH 457
Query: 610 EGIARLLIEHGSEPSLQNSYHKTAFDYA 637
++++ G +PS+ + YA
Sbjct: 458 SFTLQIMLRSGVDPSVTDKREWRPVHYA 485
Score = 58.4 bits (135), Expect = 1e-07
Identities = 33/121 (27%), Positives = 61/121 (50%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ + +TA H AA G D LI N AN+ ++ + TPLHLAA + + +++
Sbjct: 404 DITHVTTRDWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQI 463
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
+L +G + + D P+H A+ G +G ++L+ + I ++ + +A + H
Sbjct: 464 MLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGH 523
Query: 880 L 880
L
Sbjct: 524 L 524
Score = 54.8 bits (126), Expect = 1e-06
Identities = 37/130 (28%), Positives = 65/130 (50%), Gaps = 6/130 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
H T LH A+ G + LL G++I + +A H A+ RG + L+ +GAN
Sbjct: 378 HKFTPLHWAAHSGSLECLHWLLWHGADITHVTTRDWTASHIAAIRGQDACVQALIMNGAN 437
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ ++ TPLHLA +GH ++ ++ SG ++ + ++ P+H A+ G
Sbjct: 438 LTAQDDRGCTPLHLAATHGHSFTLQIML----RSG--VDPSVTDKREWRPVHYAAFHGRL 491
Query: 611 GIARLLIEHG 620
G +LL++ G
Sbjct: 492 GCLQLLVKWG 501
Score = 53.6 bits (123), Expect = 3e-06
Identities = 32/99 (32%), Positives = 53/99 (53%)
Query: 769 FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
FT LH+AA G E + L+++ A++ + T H+AAI + ++ L+ NGAN+
Sbjct: 380 FTPLHWAAHSGSLECLHWLLWHGADITHVTTRDWTASHIAAIRGQDACVQALIMNGANLT 439
Query: 829 AIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
A D TPLH A+ G+ +I+L D ++ + E
Sbjct: 440 AQDDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKRE 478
Score = 50.8 bits (116), Expect = 2e-05
Identities = 27/91 (29%), Positives = 48/91 (52%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T LH AA +G I++ + + + +K+ P+H AA + + ++LL+ G
Sbjct: 442 DDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWG 501
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLS 855
+I +D N P+H A+ G++ K L+S
Sbjct: 502 CSIEDVDYNGNLPVHLAAMEGHLHCFKFLVS 532
Score = 36.3 bits (80), Expect = 0.48
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARN-TPLHDASETGNIGAA 850
AN R K +H A + ++ GA+IN +DV TPLH A+ +G++
Sbjct: 336 ANPCSRKKMHFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECL 395
Query: 851 KILLSYNPDITLLNATEKTALAVA 874
LL + DIT + + TA +A
Sbjct: 396 HWLLWHGADITHVTTRDWTASHIA 419
>DQ508815-1|ABF60230.1| 593|Homo sapiens SARP protein.
Length = 593
Score = 80.2 bits (189), Expect = 3e-14
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 2/132 (1%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T++D G T LH+A+ HG + ++ +L G + + TD E +HYA+ G L +L
Sbjct: 210 LTAQDDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLL 269
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ G +I + + N P+HLA GHLHC K ++ + S + N++G L LA
Sbjct: 270 VKWGCSIEDVDYNGNLPVHLAAMEGHLHCFKFLV--SRMSSATQVLKAFNDNGENVLDLA 327
Query: 605 SKWGYEGIARLL 616
++ + I + +
Sbjct: 328 QRFFKQNILQFI 339
Score = 69.3 bits (162), Expect = 6e-11
Identities = 39/137 (28%), Positives = 72/137 (52%), Gaps = 6/137 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T + G TA H+A+I G+ V+ L+ G+ + A D C+ LH A++ GH L ++
Sbjct: 177 ITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIM 236
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L SG + + + + P+H A +G L C++ ++ + +I + +GN P+HLA
Sbjct: 237 LRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWG------CSIEDVDYNGNLPVHLA 290
Query: 605 SKWGYEGIARLLIEHGS 621
+ G+ + L+ S
Sbjct: 291 AMEGHLHCFKFLVSRMS 307
Score = 61.3 bits (142), Expect = 1e-08
Identities = 88/344 (25%), Positives = 140/344 (40%), Gaps = 37/344 (10%)
Query: 496 LHVASIHG--KATIVETLLEM---GSEINATD-LNECSALHYASSRGHQNVLLMLLHSGA 549
+H SIH +A V+ L E+ G+ IN D L++ + LH+A+ G L LL GA
Sbjct: 116 VHFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGA 175
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+I T H+A G CV+A+I N+ ++ G TPLHLA+ G+
Sbjct: 176 DITHVTTRGWTASHIAAIRGQDACVQALIM------NGANLTAQDDRGCTPLHLAATHGH 229
Query: 610 EGIARLLIEHGSEPSLQNSYHKTAFDYA--H-NLRILQVLK--SCTPNLFEY-----IHI 659
++++ G +PS+ + YA H L LQ+L C+ +Y +H+
Sbjct: 230 SFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHL 289
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
+ E + C + + LK ND + + L L +R + + F
Sbjct: 290 AAME-GHLHCFKFLVSRMSSATQVLKA--FNDNGENV--LDLAQRFFKQ------NILQF 338
Query: 720 YMNIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAA 776
+Y D+E H + K+ E ++N NG T +H AA
Sbjct: 339 IQGAEYEGKDLEDQETLAFPGHVAAFKGDLGMLKKLVEDGV-ININERADNGSTPMHKAA 397
Query: 777 RYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
G E LI A+ N NK + P +A ++LL
Sbjct: 398 GQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVKLL 441
Score = 61.3 bits (142), Expect = 1e-08
Identities = 34/121 (28%), Positives = 62/121 (51%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ + G+TA H AA G D LI N AN+ ++ + TPLHLAA + + +++
Sbjct: 176 DITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQI 235
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
+L +G + + D P+H A+ G +G ++L+ + I ++ + +A + H
Sbjct: 236 MLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGH 295
Query: 880 L 880
L
Sbjct: 296 L 296
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/99 (32%), Positives = 53/99 (53%)
Query: 769 FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
FT LH+AA G E + L+++ A++ + T H+AAI + ++ L+ NGAN+
Sbjct: 152 FTPLHWAAHSGSLECLHWLLWHGADITHVTTRGWTASHIAAIRGQDACVQALIMNGANLT 211
Query: 829 AIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
A D TPLH A+ G+ +I+L D ++ + E
Sbjct: 212 AQDDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKRE 250
Score = 53.2 bits (122), Expect = 4e-06
Identities = 37/130 (28%), Positives = 64/130 (49%), Gaps = 6/130 (4%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
H T LH A+ G + LL G++I +A H A+ RG + L+ +GAN
Sbjct: 150 HKFTPLHWAAHSGSLECLHWLLWHGADITHVTTRGWTASHIAAIRGQDACVQALIMNGAN 209
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ ++ TPLHLA +GH ++ ++ SG ++ + ++ P+H A+ G
Sbjct: 210 LTAQDDRGCTPLHLAATHGHSFTLQIML----RSG--VDPSVTDKREWRPVHYAAFHGRL 263
Query: 611 GIARLLIEHG 620
G +LL++ G
Sbjct: 264 GCLQLLVKWG 273
Score = 50.8 bits (116), Expect = 2e-05
Identities = 27/91 (29%), Positives = 48/91 (52%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T LH AA +G I++ + + + +K+ P+H AA + + ++LL+ G
Sbjct: 214 DDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWG 273
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLS 855
+I +D N P+H A+ G++ K L+S
Sbjct: 274 CSIEDVDYNGNLPVHLAAMEGHLHCFKFLVS 304
Score = 41.5 bits (93), Expect = 0.013
Identities = 43/167 (25%), Positives = 76/167 (45%), Gaps = 15/167 (8%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSE----INATDLNECSALHYASSRGHQNVLLML 544
D +G +H+A++ G + L+ S + A + N + L A QN+L +
Sbjct: 280 DYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFI 339
Query: 545 LHSGANINQKNI-DKNT---PLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
GA K++ D+ T P H+A G L +K ++ ININ ++G+TP
Sbjct: 340 --QGAEYEGKDLEDQETLAFPGHVAAFKGDLGMLKKLV-----EDGVININERADNGSTP 392
Query: 601 LHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+H A+ G+ + LI+ G++ ++ N + D A L +K
Sbjct: 393 MHKAAGQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVK 439
Score = 40.3 bits (90), Expect = 0.030
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 804 PLHLAAINNKTVVIRLLLDNGA-NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITL 862
P H+AA +++ L+++G NIN +TP+H A+ G+I + L+ D +
Sbjct: 358 PGHVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNI 417
Query: 863 LNATEKTALAVAKDKVHLTIIDLID 887
N + VAK HL + L++
Sbjct: 418 TNKAGERPSDVAKRFAHLAAVKLLE 442
Score = 39.9 bits (89), Expect = 0.039
Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 6/116 (5%)
Query: 497 HVASIHGKATIVETLLEMGS-EINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKN 555
HVA+ G +++ L+E G IN N + +H A+ +GH L L+ GA+ N N
Sbjct: 360 HVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITN 419
Query: 556 IDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
P +A HL VK + +K +I+ NE + + G EG
Sbjct: 420 KAGERPSDVAKRFAHLAAVKLL-----EELQKYDIDDENEIDENDVKYFIRHGVEG 470
Score = 34.3 bits (75), Expect = 1.9
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Query: 796 CRNKKAQT-PLHLAAINNKTVVIRLLLDNGANINAIDVARN-TPLHDASETGNIGAAKIL 853
C KK +H A + ++ GA+IN +DV TPLH A+ +G++ L
Sbjct: 111 CSRKKVHFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWL 170
Query: 854 LSYNPDITLLNATEKTALAVA 874
L + DIT + TA +A
Sbjct: 171 LWHGADITHVTTRGWTASHIA 191
Score = 32.3 bits (70), Expect = 7.9
Identities = 18/61 (29%), Positives = 28/61 (45%)
Query: 793 NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKI 852
N+N R TP+H AA ++ L+ GA+ N + A P A ++ A K+
Sbjct: 381 NINERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVKL 440
Query: 853 L 853
L
Sbjct: 441 L 441
>BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 80.2 bits (189), Expect = 3e-14
Identities = 99/397 (24%), Positives = 169/397 (42%), Gaps = 22/397 (5%)
Query: 495 ALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
+L A G V LL+ G +N S L A S G+ + +LL AN+ +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDR 267
Query: 555 -NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N TPL A + G+L VK ++ H ++N + +GNT L A G+ I
Sbjct: 268 GNKGDITPLMAASSGGYLDIVKLLLL---HDA---DVNSQSATGNTALTYACAGGFVDIV 321
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESE- 672
++L+ G+ N T A + ++V + + I+ S+E K+ +
Sbjct: 322 KVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDH-GAGINTHSNEFKESALTLAC 380
Query: 673 KPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPD 732
L + L+ + KT E + ++ A G V++A ++ + D
Sbjct: 381 YKGHLDMVRFLLEAG-ADQEHKTDE---MHTALMEACMDGHVEVARLLLDSGAQVNMPAD 436
Query: 733 KEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSN--GFTALHYAARYGLDEFCNILIFN 790
+S L C + N+ + N G+T L AAR G +E +L+
Sbjct: 437 SFESPLT---LAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQ 493
Query: 791 RANVNCRNKKAQ-TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
AN+N + ++ Q T L LA + V L+ GA+I ++ +TPL +AS+ G++
Sbjct: 494 GANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLMEASQEGHLEL 550
Query: 850 AKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
K LL+ ++ AT TAL A + H + D++
Sbjct: 551 VKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Score = 62.5 bits (145), Expect = 6e-09
Identities = 44/141 (31%), Positives = 74/141 (52%), Gaps = 5/141 (3%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L AS G IV+ LL +++N+ +AL YA + G +++ +LL+ GANI
Sbjct: 273 ITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIE 332
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +H G IN + +NE + L LA G+ +
Sbjct: 333 DHNENGHTPLMEAASAGHVEVARVLL---DH-GAGINTH-SNEFKESALTLACYKGHLDM 387
Query: 613 ARLLIEHGSEPSLQNSYHKTA 633
R L+E G++ + TA
Sbjct: 388 VRFLLEAGADQEHKTDEMHTA 408
Score = 61.7 bits (143), Expect = 1e-08
Identities = 93/379 (24%), Positives = 155/379 (40%), Gaps = 31/379 (8%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A S G N + LL G ++N+ + + L LA + G+ + ++ A H+ +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVE 265
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ N+ TPL AS GY I +LL+ H ++ + Q++ TA YA
Sbjct: 266 ---DRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYA---------- 312
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
C + + + +E I +E + ++ A +++ I
Sbjct: 313 -CAGGFVDIVKVLLNEGANIEDHNENGHTPLME--AASAGHVEVARVLLDHGAGINTHSN 369
Query: 708 AISYGDVKLACFYMNIDYSAFI----APDKEKSNSLCHPLCE-CQYCKRKTESC---TDF 759
+ LAC+ ++D F+ A + K++ + L E C + +
Sbjct: 370 EFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGA 429
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN+ + + L AA G E +LI AN+ N + TPL AA ++ L
Sbjct: 430 QVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVAL 489
Query: 820 LLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GANINA + + T L A G A L+ DI L T L A +
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL---GCSTPLMEASQEG 546
Query: 879 HLTIID-LIDNYANKYANT 896
HL ++ L+ + AN +A T
Sbjct: 547 HLELVKYLLASGANVHATT 565
Score = 58.0 bits (134), Expect = 1e-07
Identities = 44/135 (32%), Positives = 72/135 (53%), Gaps = 9/135 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNEC--SALHYASSRGHQNVLLMLLH 546
+ +G T L A+ G + LL+ G+ IN T NE SAL A +GH +++ LL
Sbjct: 335 NENGHTPLMEAASAGHVEVARVLLDHGAGIN-THSNEFKESALTLACYKGHLDMVRFLLE 393
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ K + +T L A +GH+ + ++ SG ++N+ +S +PL LA+
Sbjct: 394 AGADQEHKTDEMHTALMEACMDGHVEVARLLL----DSGAQVNMPA--DSFESPLTLAAC 447
Query: 607 WGYEGIARLLIEHGS 621
G+ +A LLIE G+
Sbjct: 448 GGHVELAALLIERGA 462
Score = 57.6 bits (133), Expect = 2e-07
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
+AL +A G +V LLE G++ +AL A GH V +LL SGA +N
Sbjct: 374 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 433
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
+PL LA GH+ +I R N+ N+ G TPL A++ G+E +
Sbjct: 434 PADSFESPLTLAACGGHVELAALLIE------RGANLEEVNDEGYTPLMEAAREGHEEMV 487
Query: 614 RLLIEHGSEPSLQ 626
LL+ G+ + Q
Sbjct: 488 ALLLAQGANINAQ 500
Score = 56.4 bits (130), Expect = 4e-07
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL A + G + LL+ G+++N + S L A+ GH + +L+ GAN+ +
Sbjct: 407 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEE 466
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N + TPL A GH V ++ G IN E+ T L LA G+ +A
Sbjct: 467 VNDEGYTPLMEAAREGHEEMVALLL----AQGANINAQ-TEETQETALTLACCGGFSEVA 521
Query: 614 RLLIEHGSEPSL 625
LI+ G++ L
Sbjct: 522 DFLIKAGADIEL 533
Score = 52.0 bits (119), Expect = 9e-06
Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLHS 547
+ G T L A+ G +V LL G+ INA T+ + +AL A G V L+ +
Sbjct: 468 NDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA+I + +TPL A GHL VK ++ SG N++ +G+T L A +
Sbjct: 528 GADIE---LGCSTPLMEASQEGHLELVKYLL----ASG--ANVHATTATGDTALTYACEN 578
Query: 608 GYEGIARLLIEHGSE 622
G+ +A +L++ G++
Sbjct: 579 GHTDVADVLLQAGAD 593
Score = 41.1 bits (92), Expect = 0.017
Identities = 22/61 (36%), Positives = 36/61 (59%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L AS G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++++
Sbjct: 537 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDK 596
Query: 554 K 554
+
Sbjct: 597 Q 597
Score = 39.1 bits (87), Expect = 0.068
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TAL A G E + LI A++ TPL A+ +++ LL +GAN++A
Sbjct: 507 TALTLACCGGFSEVADFLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHA 563
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDI 860
+T L A E G+ A +LL D+
Sbjct: 564 TTATGDTALTYACENGHTDVADVLLQAGADL 594
>BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 80.2 bits (189), Expect = 3e-14
Identities = 99/397 (24%), Positives = 169/397 (42%), Gaps = 22/397 (5%)
Query: 495 ALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
+L A G V LL+ G +N S L A S G+ + +LL AN+ +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDR 267
Query: 555 -NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N TPL A + G+L VK ++ H ++N + +GNT L A G+ I
Sbjct: 268 GNKGDITPLMAASSGGYLDIVKLLLL---HDA---DVNSQSATGNTALTYACAGGFVDIV 321
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESE- 672
++L+ G+ N T A + ++V + + I+ S+E K+ +
Sbjct: 322 KVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDH-GAGINTHSNEFKESALTLAC 380
Query: 673 KPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPD 732
L + L+ + KT E + ++ A G V++A ++ + D
Sbjct: 381 YKGHLDMVRFLLEAG-ADQEHKTDE---MHTALMEACMDGHVEVARLLLDSGAQVNMPAD 436
Query: 733 KEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSN--GFTALHYAARYGLDEFCNILIFN 790
+S L C + N+ + N G+T L AAR G +E +L+
Sbjct: 437 SFESPLT---LAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQ 493
Query: 791 RANVNCRNKKAQ-TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
AN+N + ++ Q T L LA + V L+ GA+I ++ +TPL +AS+ G++
Sbjct: 494 GANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLMEASQEGHLEL 550
Query: 850 AKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
K LL+ ++ AT TAL A + H + D++
Sbjct: 551 VKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Score = 62.5 bits (145), Expect = 6e-09
Identities = 44/141 (31%), Positives = 74/141 (52%), Gaps = 5/141 (3%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L AS G IV+ LL +++N+ +AL YA + G +++ +LL+ GANI
Sbjct: 273 ITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIE 332
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +H G IN + +NE + L LA G+ +
Sbjct: 333 DHNENGHTPLMEAASAGHVEVARVLL---DH-GAGINTH-SNEFKESALTLACYKGHLDM 387
Query: 613 ARLLIEHGSEPSLQNSYHKTA 633
R L+E G++ + TA
Sbjct: 388 VRFLLEAGADQEHKTDEMHTA 408
Score = 61.7 bits (143), Expect = 1e-08
Identities = 93/379 (24%), Positives = 155/379 (40%), Gaps = 31/379 (8%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A S G N + LL G ++N+ + + L LA + G+ + ++ A H+ +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVE 265
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ N+ TPL AS GY I +LL+ H ++ + Q++ TA YA
Sbjct: 266 ---DRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYA---------- 312
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
C + + + +E I +E + ++ A +++ I
Sbjct: 313 -CAGGFVDIVKVLLNEGANIEDHNENGHTPLME--AASAGHVEVARVLLDHGAGINTHSN 369
Query: 708 AISYGDVKLACFYMNIDYSAFI----APDKEKSNSLCHPLCE-CQYCKRKTESC---TDF 759
+ LAC+ ++D F+ A + K++ + L E C + +
Sbjct: 370 EFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGA 429
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN+ + + L AA G E +LI AN+ N + TPL AA ++ L
Sbjct: 430 QVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVAL 489
Query: 820 LLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GANINA + + T L A G A L+ DI L T L A +
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL---GCSTPLMEASQEG 546
Query: 879 HLTIID-LIDNYANKYANT 896
HL ++ L+ + AN +A T
Sbjct: 547 HLELVKYLLASGANVHATT 565
Score = 58.0 bits (134), Expect = 1e-07
Identities = 44/135 (32%), Positives = 72/135 (53%), Gaps = 9/135 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNEC--SALHYASSRGHQNVLLMLLH 546
+ +G T L A+ G + LL+ G+ IN T NE SAL A +GH +++ LL
Sbjct: 335 NENGHTPLMEAASAGHVEVARVLLDHGAGIN-THSNEFKESALTLACYKGHLDMVRFLLE 393
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ K + +T L A +GH+ + ++ SG ++N+ +S +PL LA+
Sbjct: 394 AGADQEHKTDEMHTALMEACMDGHVEVARLLL----DSGAQVNMPA--DSFESPLTLAAC 447
Query: 607 WGYEGIARLLIEHGS 621
G+ +A LLIE G+
Sbjct: 448 GGHVELAALLIERGA 462
Score = 57.6 bits (133), Expect = 2e-07
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
+AL +A G +V LLE G++ +AL A GH V +LL SGA +N
Sbjct: 374 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 433
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
+PL LA GH+ +I R N+ N+ G TPL A++ G+E +
Sbjct: 434 PADSFESPLTLAACGGHVELAALLIE------RGANLEEVNDEGYTPLMEAAREGHEEMV 487
Query: 614 RLLIEHGSEPSLQ 626
LL+ G+ + Q
Sbjct: 488 ALLLAQGANINAQ 500
Score = 56.4 bits (130), Expect = 4e-07
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL A + G + LL+ G+++N + S L A+ GH + +L+ GAN+ +
Sbjct: 407 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEE 466
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N + TPL A GH V ++ G IN E+ T L LA G+ +A
Sbjct: 467 VNDEGYTPLMEAAREGHEEMVALLL----AQGANINAQ-TEETQETALTLACCGGFSEVA 521
Query: 614 RLLIEHGSEPSL 625
LI+ G++ L
Sbjct: 522 DFLIKAGADIEL 533
Score = 52.0 bits (119), Expect = 9e-06
Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLHS 547
+ G T L A+ G +V LL G+ INA T+ + +AL A G V L+ +
Sbjct: 468 NDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA+I + +TPL A GHL VK ++ SG N++ +G+T L A +
Sbjct: 528 GADIE---LGCSTPLMEASQEGHLELVKYLL----ASG--ANVHATTATGDTALTYACEN 578
Query: 608 GYEGIARLLIEHGSE 622
G+ +A +L++ G++
Sbjct: 579 GHTDVADVLLQAGAD 593
Score = 41.1 bits (92), Expect = 0.017
Identities = 22/61 (36%), Positives = 36/61 (59%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L AS G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++++
Sbjct: 537 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDK 596
Query: 554 K 554
+
Sbjct: 597 Q 597
Score = 39.1 bits (87), Expect = 0.068
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TAL A G E + LI A++ TPL A+ +++ LL +GAN++A
Sbjct: 507 TALTLACCGGFSEVADFLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHA 563
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDI 860
+T L A E G+ A +LL D+
Sbjct: 564 TTATGDTALTYACENGHTDVADVLLQAGADL 594
>BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 616
Score = 80.2 bits (189), Expect = 3e-14
Identities = 99/397 (24%), Positives = 169/397 (42%), Gaps = 22/397 (5%)
Query: 495 ALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
+L A G V LL+ G +N S L A S G+ + +LL AN+ +
Sbjct: 197 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDR 256
Query: 555 -NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N TPL A + G+L VK ++ H ++N + +GNT L A G+ I
Sbjct: 257 GNKGDITPLMAASSGGYLDIVKLLLL---HDA---DVNSQSATGNTALTYACAGGFVDIV 310
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESE- 672
++L+ G+ N T A + ++V + + I+ S+E K+ +
Sbjct: 311 KVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDH-GAGINTHSNEFKESALTLAC 369
Query: 673 KPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPD 732
L + L+ + KT E + ++ A G V++A ++ + D
Sbjct: 370 YKGHLDMVRFLLEAG-ADQEHKTDE---MHTALMEACMDGHVEVARLLLDSGAQVNMPAD 425
Query: 733 KEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSN--GFTALHYAARYGLDEFCNILIFN 790
+S L C + N+ + N G+T L AAR G +E +L+
Sbjct: 426 SFESPLT---LAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQ 482
Query: 791 RANVNCRNKKAQ-TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
AN+N + ++ Q T L LA + V L+ GA+I ++ +TPL +AS+ G++
Sbjct: 483 GANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLMEASQEGHLEL 539
Query: 850 AKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
K LL+ ++ AT TAL A + H + D++
Sbjct: 540 VKYLLASGANVHATTATGDTALTYACENGHTDVADVL 576
Score = 62.5 bits (145), Expect = 6e-09
Identities = 44/141 (31%), Positives = 74/141 (52%), Gaps = 5/141 (3%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L AS G IV+ LL +++N+ +AL YA + G +++ +LL+ GANI
Sbjct: 262 ITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIE 321
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +H G IN + +NE + L LA G+ +
Sbjct: 322 DHNENGHTPLMEAASAGHVEVARVLL---DH-GAGINTH-SNEFKESALTLACYKGHLDM 376
Query: 613 ARLLIEHGSEPSLQNSYHKTA 633
R L+E G++ + TA
Sbjct: 377 VRFLLEAGADQEHKTDEMHTA 397
Score = 61.7 bits (143), Expect = 1e-08
Identities = 93/379 (24%), Positives = 155/379 (40%), Gaps = 31/379 (8%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A S G N + LL G ++N+ + + L LA + G+ + ++ A H+ +
Sbjct: 197 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVE 254
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ N+ TPL AS GY I +LL+ H ++ + Q++ TA YA
Sbjct: 255 ---DRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYA---------- 301
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
C + + + +E I +E + ++ A +++ I
Sbjct: 302 -CAGGFVDIVKVLLNEGANIEDHNENGHTPLME--AASAGHVEVARVLLDHGAGINTHSN 358
Query: 708 AISYGDVKLACFYMNIDYSAFI----APDKEKSNSLCHPLCE-CQYCKRKTESC---TDF 759
+ LAC+ ++D F+ A + K++ + L E C + +
Sbjct: 359 EFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGA 418
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN+ + + L AA G E +LI AN+ N + TPL AA ++ L
Sbjct: 419 QVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVAL 478
Query: 820 LLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GANINA + + T L A G A L+ DI L T L A +
Sbjct: 479 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL---GCSTPLMEASQEG 535
Query: 879 HLTIID-LIDNYANKYANT 896
HL ++ L+ + AN +A T
Sbjct: 536 HLELVKYLLASGANVHATT 554
Score = 58.0 bits (134), Expect = 1e-07
Identities = 44/135 (32%), Positives = 72/135 (53%), Gaps = 9/135 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNEC--SALHYASSRGHQNVLLMLLH 546
+ +G T L A+ G + LL+ G+ IN T NE SAL A +GH +++ LL
Sbjct: 324 NENGHTPLMEAASAGHVEVARVLLDHGAGIN-THSNEFKESALTLACYKGHLDMVRFLLE 382
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ K + +T L A +GH+ + ++ SG ++N+ +S +PL LA+
Sbjct: 383 AGADQEHKTDEMHTALMEACMDGHVEVARLLL----DSGAQVNMPA--DSFESPLTLAAC 436
Query: 607 WGYEGIARLLIEHGS 621
G+ +A LLIE G+
Sbjct: 437 GGHVELAALLIERGA 451
Score = 57.6 bits (133), Expect = 2e-07
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
+AL +A G +V LLE G++ +AL A GH V +LL SGA +N
Sbjct: 363 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 422
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
+PL LA GH+ +I R N+ N+ G TPL A++ G+E +
Sbjct: 423 PADSFESPLTLAACGGHVELAALLIE------RGANLEEVNDEGYTPLMEAAREGHEEMV 476
Query: 614 RLLIEHGSEPSLQ 626
LL+ G+ + Q
Sbjct: 477 ALLLAQGANINAQ 489
Score = 56.4 bits (130), Expect = 4e-07
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL A + G + LL+ G+++N + S L A+ GH + +L+ GAN+ +
Sbjct: 396 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEE 455
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N + TPL A GH V ++ G IN E+ T L LA G+ +A
Sbjct: 456 VNDEGYTPLMEAAREGHEEMVALLL----AQGANINAQ-TEETQETALTLACCGGFSEVA 510
Query: 614 RLLIEHGSEPSL 625
LI+ G++ L
Sbjct: 511 DFLIKAGADIEL 522
Score = 52.0 bits (119), Expect = 9e-06
Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLHS 547
+ G T L A+ G +V LL G+ INA T+ + +AL A G V L+ +
Sbjct: 457 NDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKA 516
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA+I + +TPL A GHL VK ++ SG N++ +G+T L A +
Sbjct: 517 GADIE---LGCSTPLMEASQEGHLELVKYLL----ASG--ANVHATTATGDTALTYACEN 567
Query: 608 GYEGIARLLIEHGSE 622
G+ +A +L++ G++
Sbjct: 568 GHTDVADVLLQAGAD 582
Score = 41.1 bits (92), Expect = 0.017
Identities = 22/61 (36%), Positives = 36/61 (59%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L AS G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++++
Sbjct: 526 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDK 585
Query: 554 K 554
+
Sbjct: 586 Q 586
Score = 39.1 bits (87), Expect = 0.068
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TAL A G E + LI A++ TPL A+ +++ LL +GAN++A
Sbjct: 496 TALTLACCGGFSEVADFLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHA 552
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDI 860
+T L A E G+ A +LL D+
Sbjct: 553 TTATGDTALTYACENGHTDVADVLLQAGADL 583
>BC004457-1|AAH04457.2| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 80.2 bits (189), Expect = 3e-14
Identities = 99/397 (24%), Positives = 169/397 (42%), Gaps = 22/397 (5%)
Query: 495 ALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
+L A G V LL+ G +N S L A S G+ + +LL AN+ +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDR 267
Query: 555 -NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N TPL A + G+L VK ++ H ++N + +GNT L A G+ I
Sbjct: 268 GNKGDITPLMAASSGGYLDIVKLLLL---HDA---DVNSQSATGNTALTYACAGGFVDIV 321
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESE- 672
++L+ G+ N T A + ++V + + I+ S+E K+ +
Sbjct: 322 KVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDH-GAGINTHSNEFKESALTLAC 380
Query: 673 KPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPD 732
L + L+ + KT E + ++ A G V++A ++ + D
Sbjct: 381 YKGHLDMVRFLLEAG-ADQEHKTDE---MHTALMEACMDGHVEVARLLLDSGAQVNMPAD 436
Query: 733 KEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSN--GFTALHYAARYGLDEFCNILIFN 790
+S L C + N+ + N G+T L AAR G +E +L+
Sbjct: 437 SFESPLT---LAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQ 493
Query: 791 RANVNCRNKKAQ-TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
AN+N + ++ Q T L LA + V L+ GA+I ++ +TPL +AS+ G++
Sbjct: 494 GANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLMEASQEGHLEL 550
Query: 850 AKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
K LL+ ++ AT TAL A + H + D++
Sbjct: 551 VKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Score = 62.5 bits (145), Expect = 6e-09
Identities = 44/141 (31%), Positives = 74/141 (52%), Gaps = 5/141 (3%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L AS G IV+ LL +++N+ +AL YA + G +++ +LL+ GANI
Sbjct: 273 ITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIE 332
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +H G IN + +NE + L LA G+ +
Sbjct: 333 DHNENGHTPLMEAASAGHVEVARVLL---DH-GAGINTH-SNEFKESALTLACYKGHLDM 387
Query: 613 ARLLIEHGSEPSLQNSYHKTA 633
R L+E G++ + TA
Sbjct: 388 VRFLLEAGADQEHKTDEMHTA 408
Score = 61.7 bits (143), Expect = 1e-08
Identities = 93/379 (24%), Positives = 155/379 (40%), Gaps = 31/379 (8%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A S G N + LL G ++N+ + + L LA + G+ + ++ A H+ +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVE 265
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ N+ TPL AS GY I +LL+ H ++ + Q++ TA YA
Sbjct: 266 ---DRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYA---------- 312
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
C + + + +E I +E + ++ A +++ I
Sbjct: 313 -CAGGFVDIVKVLLNEGANIEDHNENGHTPLME--AASAGHVEVARVLLDHGAGINTHSN 369
Query: 708 AISYGDVKLACFYMNIDYSAFI----APDKEKSNSLCHPLCE-CQYCKRKTESC---TDF 759
+ LAC+ ++D F+ A + K++ + L E C + +
Sbjct: 370 EFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGA 429
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN+ + + L AA G E +LI AN+ N + TPL AA ++ L
Sbjct: 430 QVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVAL 489
Query: 820 LLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GANINA + + T L A G A L+ DI L T L A +
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL---GCSTPLMEASQEG 546
Query: 879 HLTIID-LIDNYANKYANT 896
HL ++ L+ + AN +A T
Sbjct: 547 HLELVKYLLASGANVHATT 565
Score = 58.0 bits (134), Expect = 1e-07
Identities = 44/135 (32%), Positives = 72/135 (53%), Gaps = 9/135 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNEC--SALHYASSRGHQNVLLMLLH 546
+ +G T L A+ G + LL+ G+ IN T NE SAL A +GH +++ LL
Sbjct: 335 NENGHTPLMEAASAGHVEVARVLLDHGAGIN-THSNEFKESALTLACYKGHLDMVRFLLE 393
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ K + +T L A +GH+ + ++ SG ++N+ +S +PL LA+
Sbjct: 394 AGADQEHKTDEMHTALMEACMDGHVEVARLLL----DSGAQVNMPA--DSFESPLTLAAC 447
Query: 607 WGYEGIARLLIEHGS 621
G+ +A LLIE G+
Sbjct: 448 GGHVELAALLIERGA 462
Score = 57.6 bits (133), Expect = 2e-07
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
+AL +A G +V LLE G++ +AL A GH V +LL SGA +N
Sbjct: 374 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 433
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
+PL LA GH+ +I R N+ N+ G TPL A++ G+E +
Sbjct: 434 PADSFESPLTLAACGGHVELAALLIE------RGANLEEVNDEGYTPLMEAAREGHEEMV 487
Query: 614 RLLIEHGSEPSLQ 626
LL+ G+ + Q
Sbjct: 488 ALLLAQGANINAQ 500
Score = 56.4 bits (130), Expect = 4e-07
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL A + G + LL+ G+++N + S L A+ GH + +L+ GAN+ +
Sbjct: 407 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEE 466
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N + TPL A GH V ++ G IN E+ T L LA G+ +A
Sbjct: 467 VNDEGYTPLMEAAREGHEEMVALLL----AQGANINAQ-TEETQETALTLACCGGFSEVA 521
Query: 614 RLLIEHGSEPSL 625
LI+ G++ L
Sbjct: 522 DFLIKAGADIEL 533
Score = 52.0 bits (119), Expect = 9e-06
Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLHS 547
+ G T L A+ G +V LL G+ INA T+ + +AL A G V L+ +
Sbjct: 468 NDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA+I + +TPL A GHL VK ++ SG N++ +G+T L A +
Sbjct: 528 GADIE---LGCSTPLMEASQEGHLELVKYLL----ASG--ANVHATTATGDTALTYACEN 578
Query: 608 GYEGIARLLIEHGSE 622
G+ +A +L++ G++
Sbjct: 579 GHTDVADVLLQAGAD 593
Score = 41.1 bits (92), Expect = 0.017
Identities = 22/61 (36%), Positives = 36/61 (59%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L AS G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++++
Sbjct: 537 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDK 596
Query: 554 K 554
+
Sbjct: 597 Q 597
Score = 39.1 bits (87), Expect = 0.068
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TAL A G E + LI A++ TPL A+ +++ LL +GAN++A
Sbjct: 507 TALTLACCGGFSEVADFLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHA 563
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDI 860
+T L A E G+ A +LL D+
Sbjct: 564 TTATGDTALTYACENGHTDVADVLLQAGADL 594
>AK125596-1|BAC86214.1| 235|Homo sapiens protein ( Homo sapiens
cDNA FLJ43608 fis, clone SPLEN2012624. ).
Length = 235
Score = 80.2 bits (189), Expect = 3e-14
Identities = 44/113 (38%), Positives = 64/113 (56%), Gaps = 3/113 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFC-NILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN D TALHYAA DE C +L+ AN N + TPLH AA N +R
Sbjct: 26 VNDLDGYNRTALHYAAEK--DEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRA 83
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALA 872
LL++GA++NA+D +TPL A+ GN+ + ILL Y ++ ++N +T ++
Sbjct: 84 LLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPIS 136
Score = 60.1 bits (139), Expect = 3e-08
Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D + TALH A+ +A VE LLE G+ NA D N + LH+A+ + + + LL SG
Sbjct: 30 DGYNRTALHYAAEKDEAC-VEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESG 88
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAII-YFAE 582
A++N + + +TPL A G+L V ++ Y AE
Sbjct: 89 ASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAE 123
Score = 52.0 bits (119), Expect = 9e-06
Identities = 39/142 (27%), Positives = 70/142 (49%), Gaps = 7/142 (4%)
Query: 517 EINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKA 576
++N D +ALHYA+ + V + LL GAN N + +++TPLH A + CV+A
Sbjct: 25 QVNDLDGYNRTALHYAAEKDEACVEV-LLEYGANPNALDGNRDTPLHWAAFKNNAECVRA 83
Query: 577 IIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDY 636
++ SG ++N + + +TPL A+ G +L+++G+E + N +T
Sbjct: 84 LL----ESGA--SVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPISR 137
Query: 637 AHNLRILQVLKSCTPNLFEYIH 658
L + + + FE +H
Sbjct: 138 LVALLVRGLGTEKEDSCFELLH 159
Score = 49.2 bits (112), Expect = 6e-05
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 780 LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLH 839
L +++ VN + +T LH AA ++ V +LL+ GAN NA+D R+TPLH
Sbjct: 12 LSSLSTVIVPPFLQVNDLDGYNRTALHYAAEKDEACV-EVLLEYGANPNALDGNRDTPLH 70
Query: 840 DASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
A+ N + LL + L+ T L+ A K +L + ++ +Y
Sbjct: 71 WAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDY 120
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/74 (33%), Positives = 39/74 (52%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D + T LH A+ A V LLE G+ +NA D N + L +A+ +G+ + +LL G
Sbjct: 62 DGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYG 121
Query: 549 ANINQKNIDKNTPL 562
A + N+ TP+
Sbjct: 122 AEVRVINLIGQTPI 135
>AK022041-1|BAB13958.1| 435|Homo sapiens protein ( Homo sapiens
cDNA FLJ11979 fis, clone HEMBB1001282, weakly similar to
ANKYRIN R. ).
Length = 435
Score = 80.2 bits (189), Expect = 3e-14
Identities = 99/397 (24%), Positives = 169/397 (42%), Gaps = 22/397 (5%)
Query: 495 ALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
+L A G V LL+ G +N S L A S G+ + +LL AN+ +
Sbjct: 16 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDR 75
Query: 555 -NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N TPL A + G+L VK ++ H ++N + +GNT L A G+ I
Sbjct: 76 GNKGDITPLMAASSGGYLDIVKLLLL---HDA---DVNSQSATGNTALTYACAGGFVDIV 129
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESE- 672
++L+ G+ N T A + ++V + + I+ S+E K+ +
Sbjct: 130 KVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDH-GAGINTHSNEFKESALTLAC 188
Query: 673 KPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPD 732
L + L+ + KT E + ++ A G V++A ++ + D
Sbjct: 189 YKGHLDMVRFLLEAG-ADQEHKTDE---MHTALMEACMDGHVEVARLLLDSGAQVNMPAD 244
Query: 733 KEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSN--GFTALHYAARYGLDEFCNILIFN 790
+S L C + N+ + N G+T L AAR G +E +L+
Sbjct: 245 SFESPLT---LAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQ 301
Query: 791 RANVNCRNKKAQ-TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
AN+N + ++ Q T L LA + V L+ GA+I ++ +TPL +AS+ G++
Sbjct: 302 GANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLMEASQEGHLEL 358
Query: 850 AKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
K LL+ ++ AT TAL A + H + D++
Sbjct: 359 VKYLLASGANVHATTATGDTALTYACENGHTDVADVL 395
Score = 62.5 bits (145), Expect = 6e-09
Identities = 44/141 (31%), Positives = 74/141 (52%), Gaps = 5/141 (3%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L AS G IV+ LL +++N+ +AL YA + G +++ +LL+ GANI
Sbjct: 81 ITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIE 140
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +H G IN + +NE + L LA G+ +
Sbjct: 141 DHNENGHTPLMEAASAGHVEVARVLL---DH-GAGINTH-SNEFKESALTLACYKGHLDM 195
Query: 613 ARLLIEHGSEPSLQNSYHKTA 633
R L+E G++ + TA
Sbjct: 196 VRFLLEAGADQEHKTDEMHTA 216
Score = 61.7 bits (143), Expect = 1e-08
Identities = 93/379 (24%), Positives = 155/379 (40%), Gaps = 31/379 (8%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A S G N + LL G ++N+ + + L LA + G+ + ++ A H+ +
Sbjct: 16 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVE 73
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ N+ TPL AS GY I +LL+ H ++ + Q++ TA YA
Sbjct: 74 ---DRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYA---------- 120
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
C + + + +E I +E + ++ A +++ I
Sbjct: 121 -CAGGFVDIVKVLLNEGANIEDHNENGHTPLME--AASAGHVEVARVLLDHGAGINTHSN 177
Query: 708 AISYGDVKLACFYMNIDYSAFI----APDKEKSNSLCHPLCE-CQYCKRKTESC---TDF 759
+ LAC+ ++D F+ A + K++ + L E C + +
Sbjct: 178 EFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGA 237
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN+ + + L AA G E +LI AN+ N + TPL AA ++ L
Sbjct: 238 QVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVAL 297
Query: 820 LLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GANINA + + T L A G A L+ DI L T L A +
Sbjct: 298 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL---GCSTPLMEASQEG 354
Query: 879 HLTIID-LIDNYANKYANT 896
HL ++ L+ + AN +A T
Sbjct: 355 HLELVKYLLASGANVHATT 373
Score = 58.0 bits (134), Expect = 1e-07
Identities = 44/135 (32%), Positives = 72/135 (53%), Gaps = 9/135 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNEC--SALHYASSRGHQNVLLMLLH 546
+ +G T L A+ G + LL+ G+ IN T NE SAL A +GH +++ LL
Sbjct: 143 NENGHTPLMEAASAGHVEVARVLLDHGAGIN-THSNEFKESALTLACYKGHLDMVRFLLE 201
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ K + +T L A +GH+ + ++ SG ++N+ +S +PL LA+
Sbjct: 202 AGADQEHKTDEMHTALMEACMDGHVEVARLLL----DSGAQVNMPA--DSFESPLTLAAC 255
Query: 607 WGYEGIARLLIEHGS 621
G+ +A LLIE G+
Sbjct: 256 GGHVELAALLIERGA 270
Score = 57.6 bits (133), Expect = 2e-07
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
+AL +A G +V LLE G++ +AL A GH V +LL SGA +N
Sbjct: 182 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 241
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
+PL LA GH+ +I R N+ N+ G TPL A++ G+E +
Sbjct: 242 PADSFESPLTLAACGGHVELAALLIE------RGANLEEVNDEGYTPLMEAAREGHEEMV 295
Query: 614 RLLIEHGSEPSLQ 626
LL+ G+ + Q
Sbjct: 296 ALLLAQGANINAQ 308
Score = 56.4 bits (130), Expect = 4e-07
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL A + G + LL+ G+++N + S L A+ GH + +L+ GAN+ +
Sbjct: 215 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEE 274
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N + TPL A GH V ++ G IN E+ T L LA G+ +A
Sbjct: 275 VNDEGYTPLMEAAREGHEEMVALLL----AQGANINAQ-TEETQETALTLACCGGFSEVA 329
Query: 614 RLLIEHGSEPSL 625
LI+ G++ L
Sbjct: 330 DFLIKAGADIEL 341
Score = 52.0 bits (119), Expect = 9e-06
Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLHS 547
+ G T L A+ G +V LL G+ INA T+ + +AL A G V L+ +
Sbjct: 276 NDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKA 335
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA+I + +TPL A GHL VK ++ SG N++ +G+T L A +
Sbjct: 336 GADIE---LGCSTPLMEASQEGHLELVKYLL----ASG--ANVHATTATGDTALTYACEN 386
Query: 608 GYEGIARLLIEHGSE 622
G+ +A +L++ G++
Sbjct: 387 GHTDVADVLLQAGAD 401
Score = 41.1 bits (92), Expect = 0.017
Identities = 22/61 (36%), Positives = 36/61 (59%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L AS G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++++
Sbjct: 345 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDK 404
Query: 554 K 554
+
Sbjct: 405 Q 405
Score = 39.1 bits (87), Expect = 0.068
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TAL A G E + LI A++ TPL A+ +++ LL +GAN++A
Sbjct: 315 TALTLACCGGFSEVADFLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHA 371
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDI 860
+T L A E G+ A +LL D+
Sbjct: 372 TTATGDTALTYACENGHTDVADVLLQAGADL 402
>AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeats
single KH domain protein isoform 2 protein.
Length = 2617
Score = 80.2 bits (189), Expect = 3e-14
Identities = 91/398 (22%), Positives = 166/398 (41%), Gaps = 20/398 (5%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L AS G IV+ LL +++N+ +AL YA + G +++ +LL+ GANI
Sbjct: 273 ITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIE 332
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +H G IN + +NE + L LA G+ +
Sbjct: 333 DHNENGHTPLMEAASAGHVEVARVLL---DH-GAGINTH-SNEFKESALTLACYKGHLDM 387
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPNLFEYIHITSSEVKKISC 669
R L+E G++ + TA A ++ + ++L + S + +C
Sbjct: 388 VRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 447
Query: 670 ESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI 729
+ L + ND T ++ A G ++ + + A I
Sbjct: 448 GGHVELAALLIERGANLEEVNDEGYT--------PLMEAAREGHEEMVA--LLLAQGANI 497
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
E++ L C + ++ + T L A++ G E L+
Sbjct: 498 NAQTEETQETALTLACCGGFSEVADFLIKAGADI-ELGCSTPLMEASQEGHLELVKYLLA 556
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
+ ANV+ T L A N T V +LL GA++ TPL A+ G++
Sbjct: 557 SGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCT 616
Query: 850 AKILLSYNPDITLLNA-TEKTALAVAKDKVHLTIIDLI 886
+ L+S ++ A + T +++A HL +++L+
Sbjct: 617 VQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 654
Score = 79.0 bits (186), Expect = 7e-14
Identities = 47/140 (33%), Positives = 80/140 (57%), Gaps = 5/140 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLH 546
RD G T L +A+ G +VE LL+ G +I A ++ + + L A S G Q V+ +LL
Sbjct: 1084 RDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLA 1143
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GAN +N+ TPL LA + G+++ +K ++ ++G +IN ++ G +PL LA+
Sbjct: 1144 RGANKEHRNVSDYTPLSLAASGGYVNIIKILL----NAGAEINSRTGSKLGISPLMLAAM 1199
Query: 607 WGYEGIARLLIEHGSEPSLQ 626
G+ +LL++ GS+ + Q
Sbjct: 1200 NGHVPAVKLLLDMGSDINAQ 1219
Score = 77.4 bits (182), Expect = 2e-13
Identities = 83/338 (24%), Positives = 146/338 (43%), Gaps = 14/338 (4%)
Query: 521 TDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
T+ N +AL A + GH+ ++ +L+ A I ++ TPL LA GH+ V+ ++
Sbjct: 1051 TESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILL-- 1108
Query: 581 AEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNL 640
G I + + +TPL LA G + + LL+ G+ +N T A +
Sbjct: 1109 --DKGGDIEAQ-SERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASG 1165
Query: 641 RILQVLKSCTPNLFEYIHITSSE--VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN 698
+ ++K E T S+ + + + ++ L SD N +T N
Sbjct: 1166 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN 1225
Query: 699 LKLIERILRAISYGDVKLACFYMNIDYSAF--IAPDKEKSNSLCHPLCECQYCKRKTESC 756
L + + L N+++ A + P E ++ + + +
Sbjct: 1226 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASG-----GYAEVGRVLLDKG 1280
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
D + S+ TAL AA G +FC +LI A+++ RNKK TPL LA+ V
Sbjct: 1281 ADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDV 1340
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
++LL+ GA+++A D + TPL A G++ + L+
Sbjct: 1341 VQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV 1378
Score = 68.9 bits (161), Expect = 7e-11
Identities = 44/131 (33%), Positives = 69/131 (52%), Gaps = 5/131 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L AS G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++
Sbjct: 537 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 596
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A GHL V+ +I G +N AN + +T + LA G+ +
Sbjct: 597 ESEGGRTPLMKAARAGHLCTVQFLI----SKGANVNRATAN-NDHTVVSLACAGGHLAVV 651
Query: 614 RLLIEHGSEPS 624
LL+ HG++P+
Sbjct: 652 ELLLAHGADPT 662
Score = 64.9 bits (151), Expect = 1e-09
Identities = 42/133 (31%), Positives = 72/133 (54%), Gaps = 8/133 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDL--NECSALHYASSRGHQNVLLMLL 545
R GLT L A+ G A + LL+ G+++NA + + +AL A+ +GH +L+
Sbjct: 1253 RAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLI 1312
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
H GA+I+ +N NTPL LA N GH V+ ++ +G +++ A+ TPL A
Sbjct: 1313 HRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLV----QAG--ADVDAADNRKITPLMSAF 1366
Query: 606 KWGYEGIARLLIE 618
+ G+ + + L++
Sbjct: 1367 RKGHVKVVQYLVK 1379
Score = 64.5 bits (150), Expect = 2e-09
Identities = 41/131 (31%), Positives = 70/131 (53%), Gaps = 8/131 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL +A G+A +V LL+ + + + L A+S G+ V +LL GA++N
Sbjct: 1226 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 1285
Query: 554 KNI--DKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ ++T L +A + GH + +I H G I++ N+ GNTPL LAS G+
Sbjct: 1286 PPVPSSRDTALTIAADKGHYKFCELLI----HRGAHIDVR--NKKGNTPLWLASNGGHFD 1339
Query: 612 IARLLIEHGSE 622
+ +LL++ G++
Sbjct: 1340 VVQLLVQAGAD 1350
Score = 61.7 bits (143), Expect = 1e-08
Identities = 93/379 (24%), Positives = 155/379 (40%), Gaps = 31/379 (8%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A S G N + LL G ++N+ + + L LA + G+ + ++ A H+ +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVE 265
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ N+ TPL AS GY I +LL+ H ++ + Q++ TA YA
Sbjct: 266 ---DRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYA---------- 312
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
C + + + +E I +E + ++ A +++ I
Sbjct: 313 -CAGGFVDIVKVLLNEGANIEDHNENGHTPLME--AASAGHVEVARVLLDHGAGINTHSN 369
Query: 708 AISYGDVKLACFYMNIDYSAFI----APDKEKSNSLCHPLCE-CQYCKRKTESC---TDF 759
+ LAC+ ++D F+ A + K++ + L E C + +
Sbjct: 370 EFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGA 429
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN+ + + L AA G E +LI AN+ N + TPL AA ++ L
Sbjct: 430 QVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVAL 489
Query: 820 LLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GANINA + + T L A G A L+ DI L T L A +
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL---GCSTPLMEASQEG 546
Query: 879 HLTIID-LIDNYANKYANT 896
HL ++ L+ + AN +A T
Sbjct: 547 HLELVKYLLASGANVHATT 565
Score = 60.9 bits (141), Expect = 2e-08
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D D + +SN TAL A G +E ++LI A + R+KK TPL LAA V+
Sbjct: 1046 DIDAHT-ESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVV 1104
Query: 818 RLLLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD G +I A + ++TPL A G +LL+ + N ++ T L++A
Sbjct: 1105 EILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAAS 1164
Query: 877 KVHLTIIDLIDN 888
++ II ++ N
Sbjct: 1165 GGYVNIIKILLN 1176
Score = 60.9 bits (141), Expect = 2e-08
Identities = 42/130 (32%), Positives = 67/130 (51%), Gaps = 3/130 (2%)
Query: 760 DVNV-CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
D+N ++N TAL A G E ++L+ +ANV R K TPL AA V R
Sbjct: 1215 DINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGR 1274
Query: 819 LLLDNGANINA--IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD GA++NA + +R+T L A++ G+ ++L+ I + N T L +A +
Sbjct: 1275 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASN 1334
Query: 877 KVHLTIIDLI 886
H ++ L+
Sbjct: 1335 GGHFDVVQLL 1344
Score = 60.5 bits (140), Expect = 3e-08
Identities = 43/149 (28%), Positives = 72/149 (48%), Gaps = 5/149 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINAT-DLNECSALHYASSRGHQNVLLMLLHSGAN 550
G++ L +A+++G V+ LL+MGS+INA + N +AL A +G V+ +LL AN
Sbjct: 1190 GISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKAN 1249
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ + TPL A + G+ + ++ G +N S +T L +A+ G+
Sbjct: 1250 VEHRAKTGLTPLMEAASGGYAEVGRVLL----DKGADVNAPPVPSSRDTALTIAADKGHY 1305
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
LLI G+ ++N T A N
Sbjct: 1306 KFCELLIHRGAHIDVRNKKGNTPLWLASN 1334
Score = 58.0 bits (134), Expect = 1e-07
Identities = 44/135 (32%), Positives = 72/135 (53%), Gaps = 9/135 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNEC--SALHYASSRGHQNVLLMLLH 546
+ +G T L A+ G + LL+ G+ IN T NE SAL A +GH +++ LL
Sbjct: 335 NENGHTPLMEAASAGHVEVARVLLDHGAGIN-THSNEFKESALTLACYKGHLDMVRFLLE 393
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ K + +T L A +GH+ + ++ SG ++N+ +S +PL LA+
Sbjct: 394 AGADQEHKTDEMHTALMEACMDGHVEVARLLL----DSGAQVNMPA--DSFESPLTLAAC 447
Query: 607 WGYEGIARLLIEHGS 621
G+ +A LLIE G+
Sbjct: 448 GGHVELAALLIERGA 462
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/126 (32%), Positives = 62/126 (49%), Gaps = 4/126 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L A G E ++L+ AN RN TPL LAA +I++LL+ GA IN+
Sbjct: 1124 TPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS 1183
Query: 830 IDVAR--NTPLHDASETGNIGAAKILLSYNPDITL-LNATEKTALAVAKDKVHLTIID-L 885
++ +PL A+ G++ A K+LL DI + TAL +A + ++ L
Sbjct: 1184 RTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 1243
Query: 886 IDNYAN 891
+D AN
Sbjct: 1244 LDRKAN 1249
Score = 52.8 bits (121), Expect = 5e-06
Identities = 80/340 (23%), Positives = 133/340 (39%), Gaps = 16/340 (4%)
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
+T L LA GH V +I R I ++ G TPL LA+ G+ G+ +L++
Sbjct: 1056 DTALTLACAGGHEELVSVLI------ARDAKIEHRDKKGFTPLILAATAGHVGVVEILLD 1109
Query: 619 HGSEPSLQNSYHK-TAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G + Q+ K T A + +V+ H S+ +S +
Sbjct: 1110 KGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVN 1169
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ L ++ N S+T L + +L A++ G V + +D + I E +
Sbjct: 1170 IIKILLNAGAEIN--SRTGSKLGISPLMLAAMN-GHVPAV--KLLLDMGSDINAQIETNR 1224
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCD--SNGFTALHYAARYGLDEFCNILIFNRANVN 795
+ L Q D NV G T L AA G E +L+ A+VN
Sbjct: 1225 NTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVN 1284
Query: 796 CRN--KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
T L +AA LL+ GA+I+ + NTPL AS G+ ++L
Sbjct: 1285 APPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLL 1344
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKY 893
+ D+ + + T L A K H+ ++ + N++
Sbjct: 1345 VQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQF 1384
Score = 49.2 bits (112), Expect = 6e-05
Identities = 33/133 (24%), Positives = 61/133 (45%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ + G TAL YA G + ++L+ A++ ++ +TPL AA ++
Sbjct: 560 NVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQF 619
Query: 820 LLDNGANINAIDVAR-NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
L+ GAN+N +T + A G++ ++LL++ D T T L A
Sbjct: 620 LISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGG 679
Query: 879 HLTIIDLIDNYAN 891
H ++ + +Y N
Sbjct: 680 HTNVVSYLLDYPN 692
Score = 49.2 bits (112), Expect = 6e-05
Identities = 30/96 (31%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +SRD TAL +A+ G E L+ G+ I+ + + L AS+ GH +V+
Sbjct: 1287 PVPSSRD----TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQ 1342
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+L+ +GA+++ + K TPL A GH+ V+ ++
Sbjct: 1343 LLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV 1378
Score = 45.6 bits (103), Expect = 8e-04
Identities = 32/129 (24%), Positives = 61/129 (47%), Gaps = 7/129 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G TAL A +G + + LL+ G+++ + L A+ GH + L+ GAN+
Sbjct: 568 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANV 627
Query: 552 NQKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N+ + +T + LA GHL V+ ++ ++ + G+T L A+K G+
Sbjct: 628 NRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRL------KDGSTMLIEAAKGGHT 681
Query: 611 GIARLLIEH 619
+ L+++
Sbjct: 682 NVVSYLLDY 690
>AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeats
single KH domain protein isoform 1 protein.
Length = 2542
Score = 80.2 bits (189), Expect = 3e-14
Identities = 91/398 (22%), Positives = 166/398 (41%), Gaps = 20/398 (5%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L AS G IV+ LL +++N+ +AL YA + G +++ +LL+ GANI
Sbjct: 273 ITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIE 332
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +H G IN + +NE + L LA G+ +
Sbjct: 333 DHNENGHTPLMEAASAGHVEVARVLL---DH-GAGINTH-SNEFKESALTLACYKGHLDM 387
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPNLFEYIHITSSEVKKISC 669
R L+E G++ + TA A ++ + ++L + S + +C
Sbjct: 388 VRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 447
Query: 670 ESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI 729
+ L + ND T ++ A G ++ + + A I
Sbjct: 448 GGHVELAALLIERGANLEEVNDEGYT--------PLMEAAREGHEEMVA--LLLAQGANI 497
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
E++ L C + ++ + T L A++ G E L+
Sbjct: 498 NAQTEETQETALTLACCGGFSEVADFLIKAGADI-ELGCSTPLMEASQEGHLELVKYLLA 556
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
+ ANV+ T L A N T V +LL GA++ TPL A+ G++
Sbjct: 557 SGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCT 616
Query: 850 AKILLSYNPDITLLNA-TEKTALAVAKDKVHLTIIDLI 886
+ L+S ++ A + T +++A HL +++L+
Sbjct: 617 VQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 654
Score = 79.0 bits (186), Expect = 7e-14
Identities = 47/140 (33%), Positives = 80/140 (57%), Gaps = 5/140 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLH 546
RD G T L +A+ G +VE LL+ G +I A ++ + + L A S G Q V+ +LL
Sbjct: 1084 RDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLA 1143
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GAN +N+ TPL LA + G+++ +K ++ ++G +IN ++ G +PL LA+
Sbjct: 1144 RGANKEHRNVSDYTPLSLAASGGYVNIIKILL----NAGAEINSRTGSKLGISPLMLAAM 1199
Query: 607 WGYEGIARLLIEHGSEPSLQ 626
G+ +LL++ GS+ + Q
Sbjct: 1200 NGHVPAVKLLLDMGSDINAQ 1219
Score = 77.4 bits (182), Expect = 2e-13
Identities = 83/338 (24%), Positives = 146/338 (43%), Gaps = 14/338 (4%)
Query: 521 TDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
T+ N +AL A + GH+ ++ +L+ A I ++ TPL LA GH+ V+ ++
Sbjct: 1051 TESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILL-- 1108
Query: 581 AEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNL 640
G I + + +TPL LA G + + LL+ G+ +N T A +
Sbjct: 1109 --DKGGDIEAQ-SERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASG 1165
Query: 641 RILQVLKSCTPNLFEYIHITSSE--VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN 698
+ ++K E T S+ + + + ++ L SD N +T N
Sbjct: 1166 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN 1225
Query: 699 LKLIERILRAISYGDVKLACFYMNIDYSAF--IAPDKEKSNSLCHPLCECQYCKRKTESC 756
L + + L N+++ A + P E ++ + + +
Sbjct: 1226 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASG-----GYAEVGRVLLDKG 1280
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
D + S+ TAL AA G +FC +LI A+++ RNKK TPL LA+ V
Sbjct: 1281 ADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDV 1340
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
++LL+ GA+++A D + TPL A G++ + L+
Sbjct: 1341 VQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV 1378
Score = 68.9 bits (161), Expect = 7e-11
Identities = 44/131 (33%), Positives = 69/131 (52%), Gaps = 5/131 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L AS G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++
Sbjct: 537 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 596
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A GHL V+ +I G +N AN + +T + LA G+ +
Sbjct: 597 ESEGGRTPLMKAARAGHLCTVQFLI----SKGANVNRATAN-NDHTVVSLACAGGHLAVV 651
Query: 614 RLLIEHGSEPS 624
LL+ HG++P+
Sbjct: 652 ELLLAHGADPT 662
Score = 64.9 bits (151), Expect = 1e-09
Identities = 42/133 (31%), Positives = 72/133 (54%), Gaps = 8/133 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDL--NECSALHYASSRGHQNVLLMLL 545
R GLT L A+ G A + LL+ G+++NA + + +AL A+ +GH +L+
Sbjct: 1253 RAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLI 1312
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
H GA+I+ +N NTPL LA N GH V+ ++ +G +++ A+ TPL A
Sbjct: 1313 HRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLV----QAG--ADVDAADNRKITPLMSAF 1366
Query: 606 KWGYEGIARLLIE 618
+ G+ + + L++
Sbjct: 1367 RKGHVKVVQYLVK 1379
Score = 64.5 bits (150), Expect = 2e-09
Identities = 41/131 (31%), Positives = 70/131 (53%), Gaps = 8/131 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL +A G+A +V LL+ + + + L A+S G+ V +LL GA++N
Sbjct: 1226 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 1285
Query: 554 KNI--DKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ ++T L +A + GH + +I H G I++ N+ GNTPL LAS G+
Sbjct: 1286 PPVPSSRDTALTIAADKGHYKFCELLI----HRGAHIDVR--NKKGNTPLWLASNGGHFD 1339
Query: 612 IARLLIEHGSE 622
+ +LL++ G++
Sbjct: 1340 VVQLLVQAGAD 1350
Score = 61.7 bits (143), Expect = 1e-08
Identities = 93/379 (24%), Positives = 155/379 (40%), Gaps = 31/379 (8%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A S G N + LL G ++N+ + + L LA + G+ + ++ A H+ +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVE 265
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ N+ TPL AS GY I +LL+ H ++ + Q++ TA YA
Sbjct: 266 ---DRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYA---------- 312
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
C + + + +E I +E + ++ A +++ I
Sbjct: 313 -CAGGFVDIVKVLLNEGANIEDHNENGHTPLME--AASAGHVEVARVLLDHGAGINTHSN 369
Query: 708 AISYGDVKLACFYMNIDYSAFI----APDKEKSNSLCHPLCE-CQYCKRKTESC---TDF 759
+ LAC+ ++D F+ A + K++ + L E C + +
Sbjct: 370 EFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGA 429
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN+ + + L AA G E +LI AN+ N + TPL AA ++ L
Sbjct: 430 QVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVAL 489
Query: 820 LLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GANINA + + T L A G A L+ DI L T L A +
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL---GCSTPLMEASQEG 546
Query: 879 HLTIID-LIDNYANKYANT 896
HL ++ L+ + AN +A T
Sbjct: 547 HLELVKYLLASGANVHATT 565
Score = 60.9 bits (141), Expect = 2e-08
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D D + +SN TAL A G +E ++LI A + R+KK TPL LAA V+
Sbjct: 1046 DIDAHT-ESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVV 1104
Query: 818 RLLLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD G +I A + ++TPL A G +LL+ + N ++ T L++A
Sbjct: 1105 EILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAAS 1164
Query: 877 KVHLTIIDLIDN 888
++ II ++ N
Sbjct: 1165 GGYVNIIKILLN 1176
Score = 60.9 bits (141), Expect = 2e-08
Identities = 42/130 (32%), Positives = 67/130 (51%), Gaps = 3/130 (2%)
Query: 760 DVNV-CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
D+N ++N TAL A G E ++L+ +ANV R K TPL AA V R
Sbjct: 1215 DINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGR 1274
Query: 819 LLLDNGANINA--IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD GA++NA + +R+T L A++ G+ ++L+ I + N T L +A +
Sbjct: 1275 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASN 1334
Query: 877 KVHLTIIDLI 886
H ++ L+
Sbjct: 1335 GGHFDVVQLL 1344
Score = 60.5 bits (140), Expect = 3e-08
Identities = 43/149 (28%), Positives = 72/149 (48%), Gaps = 5/149 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINAT-DLNECSALHYASSRGHQNVLLMLLHSGAN 550
G++ L +A+++G V+ LL+MGS+INA + N +AL A +G V+ +LL AN
Sbjct: 1190 GISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKAN 1249
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ + TPL A + G+ + ++ G +N S +T L +A+ G+
Sbjct: 1250 VEHRAKTGLTPLMEAASGGYAEVGRVLL----DKGADVNAPPVPSSRDTALTIAADKGHY 1305
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
LLI G+ ++N T A N
Sbjct: 1306 KFCELLIHRGAHIDVRNKKGNTPLWLASN 1334
Score = 58.0 bits (134), Expect = 1e-07
Identities = 44/135 (32%), Positives = 72/135 (53%), Gaps = 9/135 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNEC--SALHYASSRGHQNVLLMLLH 546
+ +G T L A+ G + LL+ G+ IN T NE SAL A +GH +++ LL
Sbjct: 335 NENGHTPLMEAASAGHVEVARVLLDHGAGIN-THSNEFKESALTLACYKGHLDMVRFLLE 393
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ K + +T L A +GH+ + ++ SG ++N+ +S +PL LA+
Sbjct: 394 AGADQEHKTDEMHTALMEACMDGHVEVARLLL----DSGAQVNMPA--DSFESPLTLAAC 447
Query: 607 WGYEGIARLLIEHGS 621
G+ +A LLIE G+
Sbjct: 448 GGHVELAALLIERGA 462
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/126 (32%), Positives = 62/126 (49%), Gaps = 4/126 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L A G E ++L+ AN RN TPL LAA +I++LL+ GA IN+
Sbjct: 1124 TPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS 1183
Query: 830 IDVAR--NTPLHDASETGNIGAAKILLSYNPDITL-LNATEKTALAVAKDKVHLTIID-L 885
++ +PL A+ G++ A K+LL DI + TAL +A + ++ L
Sbjct: 1184 RTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 1243
Query: 886 IDNYAN 891
+D AN
Sbjct: 1244 LDRKAN 1249
Score = 52.8 bits (121), Expect = 5e-06
Identities = 80/340 (23%), Positives = 133/340 (39%), Gaps = 16/340 (4%)
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
+T L LA GH V +I R I ++ G TPL LA+ G+ G+ +L++
Sbjct: 1056 DTALTLACAGGHEELVSVLI------ARDAKIEHRDKKGFTPLILAATAGHVGVVEILLD 1109
Query: 619 HGSEPSLQNSYHK-TAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G + Q+ K T A + +V+ H S+ +S +
Sbjct: 1110 KGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVN 1169
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ L ++ N S+T L + +L A++ G V + +D + I E +
Sbjct: 1170 IIKILLNAGAEIN--SRTGSKLGISPLMLAAMN-GHVPAV--KLLLDMGSDINAQIETNR 1224
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCD--SNGFTALHYAARYGLDEFCNILIFNRANVN 795
+ L Q D NV G T L AA G E +L+ A+VN
Sbjct: 1225 NTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVN 1284
Query: 796 CRN--KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
T L +AA LL+ GA+I+ + NTPL AS G+ ++L
Sbjct: 1285 APPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLL 1344
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKY 893
+ D+ + + T L A K H+ ++ + N++
Sbjct: 1345 VQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQF 1384
Score = 49.2 bits (112), Expect = 6e-05
Identities = 33/133 (24%), Positives = 61/133 (45%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ + G TAL YA G + ++L+ A++ ++ +TPL AA ++
Sbjct: 560 NVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQF 619
Query: 820 LLDNGANINAIDVAR-NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
L+ GAN+N +T + A G++ ++LL++ D T T L A
Sbjct: 620 LISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGG 679
Query: 879 HLTIIDLIDNYAN 891
H ++ + +Y N
Sbjct: 680 HTNVVSYLLDYPN 692
Score = 49.2 bits (112), Expect = 6e-05
Identities = 30/96 (31%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +SRD TAL +A+ G E L+ G+ I+ + + L AS+ GH +V+
Sbjct: 1287 PVPSSRD----TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQ 1342
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+L+ +GA+++ + K TPL A GH+ V+ ++
Sbjct: 1343 LLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV 1378
Score = 45.6 bits (103), Expect = 8e-04
Identities = 32/129 (24%), Positives = 61/129 (47%), Gaps = 7/129 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G TAL A +G + + LL+ G+++ + L A+ GH + L+ GAN+
Sbjct: 568 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANV 627
Query: 552 NQKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N+ + +T + LA GHL V+ ++ ++ + G+T L A+K G+
Sbjct: 628 NRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRL------KDGSTMLIEAAKGGHT 681
Query: 611 GIARLLIEH 619
+ L+++
Sbjct: 682 NVVSYLLDY 690
>AF258557-1|AAG23760.1| 627|Homo sapiens PP2500 protein.
Length = 627
Score = 80.2 bits (189), Expect = 3e-14
Identities = 99/397 (24%), Positives = 169/397 (42%), Gaps = 22/397 (5%)
Query: 495 ALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
+L A G V LL+ G +N S L A S G+ + +LL AN+ +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDR 267
Query: 555 -NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N TPL A + G+L VK ++ H ++N + +GNT L A G+ I
Sbjct: 268 GNKGDITPLMAASSGGYLDIVKLLLL---HDA---DVNSQSATGNTALTYACAGGFVDIV 321
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESE- 672
++L+ G+ N T A + ++V + + I+ S+E K+ +
Sbjct: 322 KVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDH-GAGINTHSNEFKESALTLAC 380
Query: 673 KPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPD 732
L + L+ + KT E + ++ A G V++A ++ + D
Sbjct: 381 YKGHLDMVRFLLEAG-ADQEHKTDE---MHTALMEACMDGHVEVARLLLDSGAQVNMPAD 436
Query: 733 KEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSN--GFTALHYAARYGLDEFCNILIFN 790
+S L C + N+ + N G+T L AAR G +E +L+
Sbjct: 437 SFESPLT---LAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQ 493
Query: 791 RANVNCRNKKAQ-TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
AN+N + ++ Q T L LA + V L+ GA+I ++ +TPL +AS+ G++
Sbjct: 494 GANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLMEASQEGHLEL 550
Query: 850 AKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
K LL+ ++ AT TAL A + H + D++
Sbjct: 551 VKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Score = 62.5 bits (145), Expect = 6e-09
Identities = 44/141 (31%), Positives = 74/141 (52%), Gaps = 5/141 (3%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L AS G IV+ LL +++N+ +AL YA + G +++ +LL+ GANI
Sbjct: 273 ITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIE 332
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +H G IN + +NE + L LA G+ +
Sbjct: 333 DHNENGHTPLMEAASAGHVEVARVLL---DH-GAGINTH-SNEFKESALTLACYKGHLDM 387
Query: 613 ARLLIEHGSEPSLQNSYHKTA 633
R L+E G++ + TA
Sbjct: 388 VRFLLEAGADQEHKTDEMHTA 408
Score = 61.7 bits (143), Expect = 1e-08
Identities = 93/379 (24%), Positives = 155/379 (40%), Gaps = 31/379 (8%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A S G N + LL G ++N+ + + L LA + G+ + ++ A H+ +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVE 265
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ N+ TPL AS GY I +LL+ H ++ + Q++ TA YA
Sbjct: 266 ---DRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYA---------- 312
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
C + + + +E I +E + ++ A +++ I
Sbjct: 313 -CAGGFVDIVKVLLNEGANIEDHNENGHTPLME--AASAGHVEVARVLLDHGAGINTHSN 369
Query: 708 AISYGDVKLACFYMNIDYSAFI----APDKEKSNSLCHPLCE-CQYCKRKTESC---TDF 759
+ LAC+ ++D F+ A + K++ + L E C + +
Sbjct: 370 EFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGA 429
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN+ + + L AA G E +LI AN+ N + TPL AA ++ L
Sbjct: 430 QVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVAL 489
Query: 820 LLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GANINA + + T L A G A L+ DI L T L A +
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL---GCSTPLMEASQEG 546
Query: 879 HLTIID-LIDNYANKYANT 896
HL ++ L+ + AN +A T
Sbjct: 547 HLELVKYLLASGANVHATT 565
Score = 58.0 bits (134), Expect = 1e-07
Identities = 44/135 (32%), Positives = 72/135 (53%), Gaps = 9/135 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNEC--SALHYASSRGHQNVLLMLLH 546
+ +G T L A+ G + LL+ G+ IN T NE SAL A +GH +++ LL
Sbjct: 335 NENGHTPLMEAASAGHVEVARVLLDHGAGIN-THSNEFKESALTLACYKGHLDMVRFLLE 393
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ K + +T L A +GH+ + ++ SG ++N+ +S +PL LA+
Sbjct: 394 AGADQEHKTDEMHTALMEACMDGHVEVARLLL----DSGAQVNMPA--DSFESPLTLAAC 447
Query: 607 WGYEGIARLLIEHGS 621
G+ +A LLIE G+
Sbjct: 448 GGHVELAALLIERGA 462
Score = 57.6 bits (133), Expect = 2e-07
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
+AL +A G +V LLE G++ +AL A GH V +LL SGA +N
Sbjct: 374 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 433
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
+PL LA GH+ +I R N+ N+ G TPL A++ G+E +
Sbjct: 434 PADSFESPLTLAACGGHVELAALLIE------RGANLEEVNDEGYTPLMEAAREGHEEMV 487
Query: 614 RLLIEHGSEPSLQ 626
LL+ G+ + Q
Sbjct: 488 ALLLAQGANINAQ 500
Score = 56.4 bits (130), Expect = 4e-07
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL A + G + LL+ G+++N + S L A+ GH + +L+ GAN+ +
Sbjct: 407 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEE 466
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N + TPL A GH V ++ G IN E+ T L LA G+ +A
Sbjct: 467 VNDEGYTPLMEAAREGHEEMVALLL----AQGANINAQ-TEETQETALTLACCGGFSEVA 521
Query: 614 RLLIEHGSEPSL 625
LI+ G++ L
Sbjct: 522 DFLIKAGADIEL 533
Score = 52.0 bits (119), Expect = 9e-06
Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLHS 547
+ G T L A+ G +V LL G+ INA T+ + +AL A G V L+ +
Sbjct: 468 NDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA+I + +TPL A GHL VK ++ SG N++ +G+T L A +
Sbjct: 528 GADIE---LGCSTPLMEASQEGHLELVKYLL----ASG--ANVHATTATGDTALTYACEN 578
Query: 608 GYEGIARLLIEHGSE 622
G+ +A +L++ G++
Sbjct: 579 GHTDVADVLLQAGAD 593
Score = 41.1 bits (92), Expect = 0.017
Identities = 22/61 (36%), Positives = 36/61 (59%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L AS G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++++
Sbjct: 537 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDK 596
Query: 554 K 554
+
Sbjct: 597 Q 597
Score = 39.1 bits (87), Expect = 0.068
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TAL A G E + LI A++ TPL A+ +++ LL +GAN++A
Sbjct: 507 TALTLACCGGFSEVADFLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHA 563
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDI 860
+T L A E G+ A +LL D+
Sbjct: 564 TTATGDTALTYACENGHTDVADVLLQAGADL 594
>AK095193-1|BAC04496.1| 389|Homo sapiens protein ( Homo sapiens
cDNA FLJ37874 fis, clone BRSSN2018731, weakly similar to
ANKYRIN 1. ).
Length = 389
Score = 79.8 bits (188), Expect = 4e-14
Identities = 40/132 (30%), Positives = 69/132 (52%), Gaps = 2/132 (1%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T++D G T LH+A+ HG + ++ +L G + + TD E +HYA+ G L +L
Sbjct: 91 LTAQDDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLL 150
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ G I + + N P+HLA GHLHC K ++ + S + N++G L LA
Sbjct: 151 VKWGCGIEDVDYNGNLPVHLAAMEGHLHCFKFLV--SRMSSATQVLKAFNDNGENVLDLA 208
Query: 605 SKWGYEGIARLL 616
++ + I + +
Sbjct: 209 QRFFKQNILQFI 220
Score = 68.9 bits (161), Expect = 7e-11
Identities = 39/137 (28%), Positives = 71/137 (51%), Gaps = 6/137 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T + G TA H+A+I G+ V+ L+ G+ + A D C+ LH A++ GH L ++
Sbjct: 58 ITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIM 117
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L SG + + + + P+H A +G L C++ ++ + I + +GN P+HLA
Sbjct: 118 LRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWG------CGIEDVDYNGNLPVHLA 171
Query: 605 SKWGYEGIARLLIEHGS 621
+ G+ + L+ S
Sbjct: 172 AMEGHLHCFKFLVSRMS 188
Score = 60.9 bits (141), Expect = 2e-08
Identities = 34/121 (28%), Positives = 62/121 (51%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ + G+TA H AA G D LI N AN+ ++ + TPLHLAA + + +++
Sbjct: 57 DITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQI 116
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
+L +G + + D P+H A+ G +G ++L+ + I ++ + +A + H
Sbjct: 117 MLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCGIEDVDYNGNLPVHLAAMEGH 176
Query: 880 L 880
L
Sbjct: 177 L 177
Score = 50.4 bits (115), Expect = 3e-05
Identities = 27/91 (29%), Positives = 47/91 (51%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T LH AA +G I++ + + + +K+ P+H AA + + ++LL+ G
Sbjct: 95 DDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWG 154
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLS 855
I +D N P+H A+ G++ K L+S
Sbjct: 155 CGIEDVDYNGNLPVHLAAMEGHLHCFKFLVS 185
Score = 44.4 bits (100), Expect = 0.002
Identities = 31/110 (28%), Positives = 56/110 (50%), Gaps = 6/110 (5%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
LL G++I +A H A+ RG + L+ +GAN+ ++ TPLHLA +GH
Sbjct: 51 LLWHGADITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGH 110
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHG 620
++ ++ SG ++ + ++ P+H A+ G G +LL++ G
Sbjct: 111 SFTLQIML----RSG--VDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWG 154
Score = 43.6 bits (98), Expect = 0.003
Identities = 70/290 (24%), Positives = 111/290 (38%), Gaps = 31/290 (10%)
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GA+I T H+A G CV+A+I N+ ++ G TPLHL
Sbjct: 51 LLWHGADITHVTTRGWTASHIAAIRGQDACVQALIM------NGANLTAQDDRGCTPLHL 104
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA--H-NLRILQVLK--SCTPNLFEY-- 656
A+ G+ ++++ G +PS+ + YA H L LQ+L C +Y
Sbjct: 105 AATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCGIEDVDYNG 164
Query: 657 ---IHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGD 713
+H+ + E + C + + LK ND + + L L +R +
Sbjct: 165 NLPVHLAAME-GHLHCFKFLVSRMSSATQVLKA--FNDNGENV--LDLAQRFFKQ----- 214
Query: 714 VKLACFYMNIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFT 770
+ F +Y D+E H + K+ E ++N NG T
Sbjct: 215 -NILQFIQGAEYEGKDLEDQETLAFPGHVAAFKGDLGMLKKLVEDGV-ININERADNGST 272
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+H AA G E LI A+ N NK + P +A ++LL
Sbjct: 273 PMHKAAGQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVKLL 322
Score = 43.2 bits (97), Expect = 0.004
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 6/105 (5%)
Query: 769 FTALHYAARYG----LDEFCNI--LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLD 822
F ++H A R G L E + L+++ A++ + T H+AAI + ++ L+
Sbjct: 27 FGSIHDAVRAGDVKQLSEIVCLHWLLWHGADITHVTTRGWTASHIAAIRGQDACVQALIM 86
Query: 823 NGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
NGAN+ A D TPLH A+ G+ +I+L D ++ + E
Sbjct: 87 NGANLTAQDDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKRE 131
Score = 41.5 bits (93), Expect = 0.013
Identities = 43/167 (25%), Positives = 76/167 (45%), Gaps = 15/167 (8%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSE----INATDLNECSALHYASSRGHQNVLLML 544
D +G +H+A++ G + L+ S + A + N + L A QN+L +
Sbjct: 161 DYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFI 220
Query: 545 LHSGANINQKNI-DKNT---PLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
GA K++ D+ T P H+A G L +K ++ ININ ++G+TP
Sbjct: 221 --QGAEYEGKDLEDQETLAFPGHVAAFKGDLGMLKKLV-----EDGVININERADNGSTP 273
Query: 601 LHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+H A+ G+ + LI+ G++ ++ N + D A L +K
Sbjct: 274 MHKAAGQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVK 320
Score = 40.3 bits (90), Expect = 0.030
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 804 PLHLAAINNKTVVIRLLLDNGA-NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITL 862
P H+AA +++ L+++G NIN +TP+H A+ G+I + L+ D +
Sbjct: 239 PGHVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNI 298
Query: 863 LNATEKTALAVAKDKVHLTIIDLID 887
N + VAK HL + L++
Sbjct: 299 TNKAGERPSDVAKRFAHLAAVKLLE 323
Score = 39.9 bits (89), Expect = 0.039
Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 6/116 (5%)
Query: 497 HVASIHGKATIVETLLEMGS-EINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKN 555
HVA+ G +++ L+E G IN N + +H A+ +GH L L+ GA+ N N
Sbjct: 241 HVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITN 300
Query: 556 IDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
P +A HL VK + +K +I+ NE + + G EG
Sbjct: 301 KAGERPSDVAKRFAHLAAVKLL-----EELQKYDIDDENEIDENDVKYFIRHGVEG 351
Score = 32.3 bits (70), Expect = 7.9
Identities = 18/61 (29%), Positives = 28/61 (45%)
Query: 793 NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKI 852
N+N R TP+H AA ++ L+ GA+ N + A P A ++ A K+
Sbjct: 262 NINERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVKL 321
Query: 853 L 853
L
Sbjct: 322 L 322
>BC107056-1|AAI07057.1| 305|Homo sapiens ankyrin repeat domain 23
protein.
Length = 305
Score = 79.4 bits (187), Expect = 5e-14
Identities = 46/146 (31%), Positives = 79/146 (54%), Gaps = 6/146 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH A + G + +V LL G+ ++A DL + + + +A GH +L LL+ GA +N
Sbjct: 146 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 205
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ +TPLH+AV H C++ +I H +N ++ G+T LH A + G
Sbjct: 206 RDKIGSTPLHVAVRTRHPDCLEHLIECGAH------LNAQDKEGDTALHEAVRHGSYKAM 259
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHN 639
+LL+ +G+E ++N+ T A +
Sbjct: 260 KLLLLYGAELGVRNAASVTPVQLARD 285
Score = 63.7 bits (148), Expect = 3e-09
Identities = 41/146 (28%), Positives = 74/146 (50%), Gaps = 6/146 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GL A+ + +++ L G + NA D +ALH+A +GH ++ LL +GA +
Sbjct: 111 GLEMFLKAAAENQEYLIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATV 170
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ +++ TP+ A GHL +K ++ + G + +N ++ G+TPLH+A + +
Sbjct: 171 DARDLLDRTPVFWACRGGHLVILKQLL----NQGAR--VNARDKIGSTPLHVAVRTRHPD 224
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYA 637
LIE G+ + Q+ TA A
Sbjct: 225 CLEHLIECGAHLNAQDKEGDTALHEA 250
Score = 62.1 bits (144), Expect = 8e-09
Identities = 36/107 (33%), Positives = 56/107 (52%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T + +A R G L+ A VN R+K TPLH+A + L++ GA++NA
Sbjct: 179 TPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNA 238
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
D +T LH+A G+ A K+LL Y ++ + NA T + +A+D
Sbjct: 239 QDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVRNAASVTPVQLARD 285
Score = 60.1 bits (139), Expect = 3e-08
Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 7/140 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +RD T + A G I++ LL G+ +NA D + LH A H + L
Sbjct: 169 TVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEH 228
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L+ GA++N ++ + +T LH AV +G +K ++ + G + N + TP+ L
Sbjct: 229 LIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVR------NAASVTPVQL 282
Query: 604 ASKWGYEGIARLLIEHGSEP 623
A W GI L H + P
Sbjct: 283 ARDW-QRGIREALQAHVAHP 301
Score = 54.4 bits (125), Expect = 2e-06
Identities = 35/112 (31%), Positives = 53/112 (47%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N D TALH+A G + N L+ A V+ R+ +TP+ A V+++
Sbjct: 136 DPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQ 195
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL+ GA +NA D +TPLH A T + + L+ + + TAL
Sbjct: 196 LLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTAL 247
Score = 40.3 bits (90), Expect = 0.030
Identities = 27/83 (32%), Positives = 40/83 (48%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G T LH A R + LI A++N ++K+ T LH A + ++LL
Sbjct: 203 VNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLL 262
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L GA + + A TP+ A +
Sbjct: 263 LLYGAELGVRNAASVTPVQLARD 285
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/80 (28%), Positives = 38/80 (47%)
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
N +K +T LH A + + ++ LL GA ++A D+ TP+ A G++ K LL
Sbjct: 138 NAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLL 197
Query: 855 SYNPDITLLNATEKTALAVA 874
+ + + T L VA
Sbjct: 198 NQGARVNARDKIGSTPLHVA 217
>AY196212-1|AAO40750.1| 305|Homo sapiens muscle ankyrin repeat
protein 3 protein.
Length = 305
Score = 79.4 bits (187), Expect = 5e-14
Identities = 46/146 (31%), Positives = 79/146 (54%), Gaps = 6/146 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH A + G + +V LL G+ ++A DL + + + +A GH +L LL+ GA +N
Sbjct: 146 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 205
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ +TPLH+AV H C++ +I H +N ++ G+T LH A + G
Sbjct: 206 RDKIGSTPLHVAVRTRHPDCLEHLIECGAH------LNAQDKEGDTALHEAVRHGSYKAM 259
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHN 639
+LL+ +G+E ++N+ T A +
Sbjct: 260 KLLLLYGAELGVRNAASVTPVQLARD 285
Score = 63.7 bits (148), Expect = 3e-09
Identities = 41/146 (28%), Positives = 74/146 (50%), Gaps = 6/146 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GL A+ + +++ L G + NA D +ALH+A +GH ++ LL +GA +
Sbjct: 111 GLEMFLKAAAENQEYLIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATV 170
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ +++ TP+ A GHL +K ++ + G + +N ++ G+TPLH+A + +
Sbjct: 171 DARDLLDRTPVFWACRGGHLVILKQLL----NQGAR--VNARDKIGSTPLHVAVRTRHPD 224
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYA 637
LIE G+ + Q+ TA A
Sbjct: 225 CLEHLIECGAHLNAQDKEGDTALHEA 250
Score = 62.1 bits (144), Expect = 8e-09
Identities = 36/107 (33%), Positives = 56/107 (52%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T + +A R G L+ A VN R+K TPLH+A + L++ GA++NA
Sbjct: 179 TPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNA 238
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
D +T LH+A G+ A K+LL Y ++ + NA T + +A+D
Sbjct: 239 QDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVRNAASVTPVQLARD 285
Score = 60.1 bits (139), Expect = 3e-08
Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 7/140 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +RD T + A G I++ LL G+ +NA D + LH A H + L
Sbjct: 169 TVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEH 228
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L+ GA++N ++ + +T LH AV +G +K ++ + G + N + TP+ L
Sbjct: 229 LIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVR------NAASVTPVQL 282
Query: 604 ASKWGYEGIARLLIEHGSEP 623
A W GI L H + P
Sbjct: 283 ARDW-QRGIREALQAHVAHP 301
Score = 54.4 bits (125), Expect = 2e-06
Identities = 35/112 (31%), Positives = 53/112 (47%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N D TALH+A G + N L+ A V+ R+ +TP+ A V+++
Sbjct: 136 DPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQ 195
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL+ GA +NA D +TPLH A T + + L+ + + TAL
Sbjct: 196 LLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTAL 247
Score = 40.3 bits (90), Expect = 0.030
Identities = 27/83 (32%), Positives = 40/83 (48%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G T LH A R + LI A++N ++K+ T LH A + ++LL
Sbjct: 203 VNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLL 262
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L GA + + A TP+ A +
Sbjct: 263 LLYGAELGVRNAASVTPVQLARD 285
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/80 (28%), Positives = 38/80 (47%)
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
N +K +T LH A + + ++ LL GA ++A D+ TP+ A G++ K LL
Sbjct: 138 NAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLL 197
Query: 855 SYNPDITLLNATEKTALAVA 874
+ + + T L VA
Sbjct: 198 NQGARVNARDKIGSTPLHVA 217
>AK092564-1|BAC03915.1| 263|Homo sapiens protein ( Homo sapiens
cDNA FLJ35245 fis, clone PROST2002897, moderately
similar to Oryctolagus cuniculus CARP mRNA. ).
Length = 263
Score = 79.4 bits (187), Expect = 5e-14
Identities = 46/146 (31%), Positives = 79/146 (54%), Gaps = 6/146 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH A + G + +V LL G+ ++A DL + + + +A GH +L LL+ GA +N
Sbjct: 104 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 163
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ +TPLH+AV H C++ +I H +N ++ G+T LH A + G
Sbjct: 164 RDKIGSTPLHVAVRTRHPDCLEHLIECGAH------LNAQDKEGDTALHEAVRHGSYKAM 217
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHN 639
+LL+ +G+E ++N+ T A +
Sbjct: 218 KLLLLYGAELGVRNAASLTPVQLARD 243
Score = 62.1 bits (144), Expect = 8e-09
Identities = 36/107 (33%), Positives = 56/107 (52%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T + +A R G L+ A VN R+K TPLH+A + L++ GA++NA
Sbjct: 137 TPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNA 196
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
D +T LH+A G+ A K+LL Y ++ + NA T + +A+D
Sbjct: 197 QDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVRNAASLTPVQLARD 243
Score = 60.1 bits (139), Expect = 3e-08
Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 7/140 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +RD T + A G I++ LL G+ +NA D + LH A H + L
Sbjct: 127 TVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEH 186
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L+ GA++N ++ + +T LH AV +G +K ++ + G + N + TP+ L
Sbjct: 187 LIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVR------NAASLTPVQL 240
Query: 604 ASKWGYEGIARLLIEHGSEP 623
A W GI L H + P
Sbjct: 241 ARDW-QRGIREALQAHVAHP 259
Score = 52.4 bits (120), Expect = 7e-06
Identities = 32/102 (31%), Positives = 50/102 (49%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TALH+A G + N L+ A V+ R+ +TP+ A V+++ LL+ GA +NA
Sbjct: 104 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 163
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
D +TPLH A T + + L+ + + TAL
Sbjct: 164 RDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTAL 205
Score = 40.3 bits (90), Expect = 0.030
Identities = 27/83 (32%), Positives = 40/83 (48%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G T LH A R + LI A++N ++K+ T LH A + ++LL
Sbjct: 161 VNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLL 220
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L GA + + A TP+ A +
Sbjct: 221 LLYGAELGVRNAASLTPVQLARD 243
Score = 34.3 bits (75), Expect = 1.9
Identities = 22/76 (28%), Positives = 36/76 (47%)
Query: 799 KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
K +T LH A + + ++ LL GA ++A D+ TP+ A G++ K LL+
Sbjct: 100 KLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGA 159
Query: 859 DITLLNATEKTALAVA 874
+ + T L VA
Sbjct: 160 RVNARDKIGSTPLHVA 175
>AJ315766-1|CAC86120.1| 296|Homo sapiens Ankyrin repeat-containing
protein protein.
Length = 296
Score = 79.4 bits (187), Expect = 5e-14
Identities = 46/146 (31%), Positives = 79/146 (54%), Gaps = 6/146 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH A + G + +V LL G+ ++A DL + + + +A GH +L LL+ GA +N
Sbjct: 137 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 196
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ +TPLH+AV H C++ +I H +N ++ G+T LH A + G
Sbjct: 197 RDKIGSTPLHVAVRTRHPDCLEHLIECGAH------LNAQDKEGDTALHEAVRHGSYKAM 250
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHN 639
+LL+ +G+E ++N+ T A +
Sbjct: 251 KLLLLYGAELGVRNAASVTPVQLARD 276
Score = 63.7 bits (148), Expect = 3e-09
Identities = 41/146 (28%), Positives = 74/146 (50%), Gaps = 6/146 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GL A+ + +++ L G + NA D +ALH+A +GH ++ LL +GA +
Sbjct: 102 GLEMFLKAAAENQEYLIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATV 161
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ +++ TP+ A GHL +K ++ + G + +N ++ G+TPLH+A + +
Sbjct: 162 DARDLLDRTPVFWACRGGHLVILKQLL----NQGAR--VNARDKIGSTPLHVAVRTRHPD 215
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYA 637
LIE G+ + Q+ TA A
Sbjct: 216 CLEHLIECGAHLNAQDKEGDTALHEA 241
Score = 62.1 bits (144), Expect = 8e-09
Identities = 36/107 (33%), Positives = 56/107 (52%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T + +A R G L+ A VN R+K TPLH+A + L++ GA++NA
Sbjct: 170 TPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNA 229
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
D +T LH+A G+ A K+LL Y ++ + NA T + +A+D
Sbjct: 230 QDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVRNAASVTPVQLARD 276
Score = 60.1 bits (139), Expect = 3e-08
Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 7/140 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +RD T + A G I++ LL G+ +NA D + LH A H + L
Sbjct: 160 TVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEH 219
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L+ GA++N ++ + +T LH AV +G +K ++ + G + N + TP+ L
Sbjct: 220 LIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVR------NAASVTPVQL 273
Query: 604 ASKWGYEGIARLLIEHGSEP 623
A W GI L H + P
Sbjct: 274 ARDW-QRGIREALQAHVAHP 292
Score = 54.4 bits (125), Expect = 2e-06
Identities = 35/112 (31%), Positives = 53/112 (47%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N D TALH+A G + N L+ A V+ R+ +TP+ A V+++
Sbjct: 127 DPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQ 186
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL+ GA +NA D +TPLH A T + + L+ + + TAL
Sbjct: 187 LLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTAL 238
Score = 40.3 bits (90), Expect = 0.030
Identities = 27/83 (32%), Positives = 40/83 (48%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G T LH A R + LI A++N ++K+ T LH A + ++LL
Sbjct: 194 VNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLL 253
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L GA + + A TP+ A +
Sbjct: 254 LLYGAELGVRNAASVTPVQLARD 276
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/80 (28%), Positives = 38/80 (47%)
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
N +K +T LH A + + ++ LL GA ++A D+ TP+ A G++ K LL
Sbjct: 129 NAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLL 188
Query: 855 SYNPDITLLNATEKTALAVA 874
+ + + T L VA
Sbjct: 189 NQGARVNARDKIGSTPLHVA 208
>AF492401-1|AAO24067.1| 305|Homo sapiens diabetes related ankyrin
repeat protein protein.
Length = 305
Score = 79.4 bits (187), Expect = 5e-14
Identities = 46/146 (31%), Positives = 79/146 (54%), Gaps = 6/146 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH A + G + +V LL G+ ++A DL + + + +A GH +L LL+ GA +N
Sbjct: 146 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 205
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ +TPLH+AV H C++ +I H +N ++ G+T LH A + G
Sbjct: 206 RDKIGSTPLHVAVRTRHPDCLEHLIECGAH------LNAQDKEGDTALHEAVRHGSYKAM 259
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHN 639
+LL+ +G+E ++N+ T A +
Sbjct: 260 KLLLLYGAELGVRNAASVTPVQLARD 285
Score = 63.7 bits (148), Expect = 3e-09
Identities = 41/146 (28%), Positives = 74/146 (50%), Gaps = 6/146 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GL A+ + +++ L G + NA D +ALH+A +GH ++ LL +GA +
Sbjct: 111 GLEMFLKAAAENQEYLIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATV 170
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ +++ TP+ A GHL +K ++ + G + +N ++ G+TPLH+A + +
Sbjct: 171 DARDLLDRTPVFWACRGGHLVILKQLL----NQGAR--VNARDKIGSTPLHVAVRTRHPD 224
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYA 637
LIE G+ + Q+ TA A
Sbjct: 225 CLEHLIECGAHLNAQDKEGDTALHEA 250
Score = 62.1 bits (144), Expect = 8e-09
Identities = 36/107 (33%), Positives = 56/107 (52%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T + +A R G L+ A VN R+K TPLH+A + L++ GA++NA
Sbjct: 179 TPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNA 238
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
D +T LH+A G+ A K+LL Y ++ + NA T + +A+D
Sbjct: 239 QDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVRNAASVTPVQLARD 285
Score = 60.1 bits (139), Expect = 3e-08
Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 7/140 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +RD T + A G I++ LL G+ +NA D + LH A H + L
Sbjct: 169 TVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEH 228
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L+ GA++N ++ + +T LH AV +G +K ++ + G + N + TP+ L
Sbjct: 229 LIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVR------NAASVTPVQL 282
Query: 604 ASKWGYEGIARLLIEHGSEP 623
A W GI L H + P
Sbjct: 283 ARDW-QRGIREALQAHVAHP 301
Score = 54.4 bits (125), Expect = 2e-06
Identities = 35/112 (31%), Positives = 53/112 (47%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N D TALH+A G + N L+ A V+ R+ +TP+ A V+++
Sbjct: 136 DPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQ 195
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL+ GA +NA D +TPLH A T + + L+ + + TAL
Sbjct: 196 LLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTAL 247
Score = 40.3 bits (90), Expect = 0.030
Identities = 27/83 (32%), Positives = 40/83 (48%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G T LH A R + LI A++N ++K+ T LH A + ++LL
Sbjct: 203 VNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLL 262
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L GA + + A TP+ A +
Sbjct: 263 LLYGAELGVRNAASVTPVQLARD 285
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/80 (28%), Positives = 38/80 (47%)
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
N +K +T LH A + + ++ LL GA ++A D+ TP+ A G++ K LL
Sbjct: 138 NAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLL 197
Query: 855 SYNPDITLLNATEKTALAVA 874
+ + + T L VA
Sbjct: 198 NQGARVNARDKIGSTPLHVA 217
>AC092636-3|AAY14965.1| 305|Homo sapiens unknown protein.
Length = 305
Score = 79.4 bits (187), Expect = 5e-14
Identities = 46/146 (31%), Positives = 79/146 (54%), Gaps = 6/146 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH A + G + +V LL G+ ++A DL + + + +A GH +L LL+ GA +N
Sbjct: 146 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 205
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ +TPLH+AV H C++ +I H +N ++ G+T LH A + G
Sbjct: 206 RDKIGSTPLHVAVRTRHPDCLEHLIECGAH------LNAQDKEGDTALHEAVRHGSYKAM 259
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHN 639
+LL+ +G+E ++N+ T A +
Sbjct: 260 KLLLLYGAELGVRNAASVTPVQLARD 285
Score = 63.7 bits (148), Expect = 3e-09
Identities = 41/146 (28%), Positives = 74/146 (50%), Gaps = 6/146 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
GL A+ + +++ L G + NA D +ALH+A +GH ++ LL +GA +
Sbjct: 111 GLEMFLKAAAENQEYLIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATV 170
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ +++ TP+ A GHL +K ++ + G + +N ++ G+TPLH+A + +
Sbjct: 171 DARDLLDRTPVFWACRGGHLVILKQLL----NQGAR--VNARDKIGSTPLHVAVRTRHPD 224
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYA 637
LIE G+ + Q+ TA A
Sbjct: 225 CLEHLIECGAHLNAQDKEGDTALHEA 250
Score = 62.1 bits (144), Expect = 8e-09
Identities = 36/107 (33%), Positives = 56/107 (52%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T + +A R G L+ A VN R+K TPLH+A + L++ GA++NA
Sbjct: 179 TPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNA 238
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
D +T LH+A G+ A K+LL Y ++ + NA T + +A+D
Sbjct: 239 QDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVRNAASVTPVQLARD 285
Score = 60.1 bits (139), Expect = 3e-08
Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 7/140 (5%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +RD T + A G I++ LL G+ +NA D + LH A H + L
Sbjct: 169 TVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEH 228
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L+ GA++N ++ + +T LH AV +G +K ++ + G + N + TP+ L
Sbjct: 229 LIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVR------NAASVTPVQL 282
Query: 604 ASKWGYEGIARLLIEHGSEP 623
A W GI L H + P
Sbjct: 283 ARDW-QRGIREALQAHVAHP 301
Score = 54.4 bits (125), Expect = 2e-06
Identities = 35/112 (31%), Positives = 53/112 (47%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N D TALH+A G + N L+ A V+ R+ +TP+ A V+++
Sbjct: 136 DPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQ 195
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL 871
LL+ GA +NA D +TPLH A T + + L+ + + TAL
Sbjct: 196 LLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTAL 247
Score = 40.3 bits (90), Expect = 0.030
Identities = 27/83 (32%), Positives = 40/83 (48%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G T LH A R + LI A++N ++K+ T LH A + ++LL
Sbjct: 203 VNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLL 262
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L GA + + A TP+ A +
Sbjct: 263 LLYGAELGVRNAASVTPVQLARD 285
Score = 37.1 bits (82), Expect = 0.28
Identities = 23/80 (28%), Positives = 38/80 (47%)
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
N +K +T LH A + + ++ LL GA ++A D+ TP+ A G++ K LL
Sbjct: 138 NAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLL 197
Query: 855 SYNPDITLLNATEKTALAVA 874
+ + + T L VA
Sbjct: 198 NQGARVNARDKIGSTPLHVA 217
>AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein
protein.
Length = 968
Score = 79.0 bits (186), Expect = 7e-14
Identities = 47/140 (33%), Positives = 80/140 (57%), Gaps = 5/140 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLH 546
RD G T L +A+ G +VE LL+ G +I A ++ + + L A S G Q V+ +LL
Sbjct: 578 RDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLA 637
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GAN +N+ TPL LA + G+++ +K ++ ++G +IN ++ G +PL LA+
Sbjct: 638 RGANKEHRNVSDYTPLSLAASGGYVNIIKILL----NAGAEINSRTGSKLGISPLMLAAM 693
Query: 607 WGYEGIARLLIEHGSEPSLQ 626
G+ +LL++ GS+ + Q
Sbjct: 694 NGHVPAVKLLLDMGSDINAQ 713
Score = 77.4 bits (182), Expect = 2e-13
Identities = 83/338 (24%), Positives = 146/338 (43%), Gaps = 14/338 (4%)
Query: 521 TDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
T+ N +AL A + GH+ ++ +L+ A I ++ TPL LA GH+ V+ ++
Sbjct: 545 TESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILL-- 602
Query: 581 AEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNL 640
G I + + +TPL LA G + + LL+ G+ +N T A +
Sbjct: 603 --DKGGDIEAQ-SERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASG 659
Query: 641 RILQVLKSCTPNLFEYIHITSSE--VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN 698
+ ++K E T S+ + + + ++ L SD N +T N
Sbjct: 660 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN 719
Query: 699 LKLIERILRAISYGDVKLACFYMNIDYSAF--IAPDKEKSNSLCHPLCECQYCKRKTESC 756
L + + L N+++ A + P E ++ + + +
Sbjct: 720 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASG-----GYAEVGRVLLDKG 774
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
D + S+ TAL AA G +FC +LI A+++ RNKK TPL LA+ V
Sbjct: 775 ADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDV 834
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
++LL+ GA+++A D + TPL A G++ + L+
Sbjct: 835 VQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV 872
Score = 64.9 bits (151), Expect = 1e-09
Identities = 42/133 (31%), Positives = 72/133 (54%), Gaps = 8/133 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDL--NECSALHYASSRGHQNVLLMLL 545
R GLT L A+ G A + LL+ G+++NA + + +AL A+ +GH +L+
Sbjct: 747 RAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLI 806
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
H GA+I+ +N NTPL LA N GH V+ ++ +G +++ A+ TPL A
Sbjct: 807 HRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLV----QAG--ADVDAADNRKITPLMSAF 860
Query: 606 KWGYEGIARLLIE 618
+ G+ + + L++
Sbjct: 861 RKGHVKVVQYLVK 873
Score = 64.5 bits (150), Expect = 2e-09
Identities = 41/131 (31%), Positives = 70/131 (53%), Gaps = 8/131 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL +A G+A +V LL+ + + + L A+S G+ V +LL GA++N
Sbjct: 720 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 779
Query: 554 KNI--DKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ ++T L +A + GH + +I H G I++ N+ GNTPL LAS G+
Sbjct: 780 PPVPSSRDTALTIAADKGHYKFCELLI----HRGAHIDVR--NKKGNTPLWLASNGGHFD 833
Query: 612 IARLLIEHGSE 622
+ +LL++ G++
Sbjct: 834 VVQLLVQAGAD 844
Score = 60.9 bits (141), Expect = 2e-08
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D D + +SN TAL A G +E ++LI A + R+KK TPL LAA V+
Sbjct: 540 DIDAHT-ESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVV 598
Query: 818 RLLLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD G +I A + ++TPL A G +LL+ + N ++ T L++A
Sbjct: 599 EILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAAS 658
Query: 877 KVHLTIIDLIDN 888
++ II ++ N
Sbjct: 659 GGYVNIIKILLN 670
Score = 60.9 bits (141), Expect = 2e-08
Identities = 42/130 (32%), Positives = 67/130 (51%), Gaps = 3/130 (2%)
Query: 760 DVNV-CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
D+N ++N TAL A G E ++L+ +ANV R K TPL AA V R
Sbjct: 709 DINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGR 768
Query: 819 LLLDNGANINA--IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD GA++NA + +R+T L A++ G+ ++L+ I + N T L +A +
Sbjct: 769 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASN 828
Query: 877 KVHLTIIDLI 886
H ++ L+
Sbjct: 829 GGHFDVVQLL 838
Score = 60.5 bits (140), Expect = 3e-08
Identities = 43/149 (28%), Positives = 72/149 (48%), Gaps = 5/149 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINAT-DLNECSALHYASSRGHQNVLLMLLHSGAN 550
G++ L +A+++G V+ LL+MGS+INA + N +AL A +G V+ +LL AN
Sbjct: 684 GISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKAN 743
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ + TPL A + G+ + ++ G +N S +T L +A+ G+
Sbjct: 744 VEHRAKTGLTPLMEAASGGYAEVGRVLL----DKGADVNAPPVPSSRDTALTIAADKGHY 799
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
LLI G+ ++N T A N
Sbjct: 800 KFCELLIHRGAHIDVRNKKGNTPLWLASN 828
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/126 (32%), Positives = 62/126 (49%), Gaps = 4/126 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L A G E ++L+ AN RN TPL LAA +I++LL+ GA IN+
Sbjct: 618 TPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS 677
Query: 830 IDVAR--NTPLHDASETGNIGAAKILLSYNPDITL-LNATEKTALAVAKDKVHLTIID-L 885
++ +PL A+ G++ A K+LL DI + TAL +A + ++ L
Sbjct: 678 RTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 737
Query: 886 IDNYAN 891
+D AN
Sbjct: 738 LDRKAN 743
Score = 52.8 bits (121), Expect = 5e-06
Identities = 46/150 (30%), Positives = 72/150 (48%), Gaps = 24/150 (16%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L AS G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++++
Sbjct: 12 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDK 71
Query: 554 --------KNIDK-----------NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCAN 594
+ ID TPL A GHL V+ +I G +N AN
Sbjct: 72 QEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLI----SKGANVNRATAN 127
Query: 595 ESGNTPLHLASKWGYEGIARLLIEHGSEPS 624
+ +T + LA G+ + LL+ HG++P+
Sbjct: 128 -NDHTVVSLACAGGHLAVVELLLAHGADPT 156
Score = 52.8 bits (121), Expect = 5e-06
Identities = 80/340 (23%), Positives = 133/340 (39%), Gaps = 16/340 (4%)
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
+T L LA GH V +I R I ++ G TPL LA+ G+ G+ +L++
Sbjct: 550 DTALTLACAGGHEELVSVLI------ARDAKIEHRDKKGFTPLILAATAGHVGVVEILLD 603
Query: 619 HGSEPSLQNSYHK-TAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G + Q+ K T A + +V+ H S+ +S +
Sbjct: 604 KGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVN 663
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ L ++ N S+T L + +L A++ G V + +D + I E +
Sbjct: 664 IIKILLNAGAEIN--SRTGSKLGISPLMLAAMN-GHVPAV--KLLLDMGSDINAQIETNR 718
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCD--SNGFTALHYAARYGLDEFCNILIFNRANVN 795
+ L Q D NV G T L AA G E +L+ A+VN
Sbjct: 719 NTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVN 778
Query: 796 CRN--KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
T L +AA LL+ GA+I+ + NTPL AS G+ ++L
Sbjct: 779 APPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLL 838
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKY 893
+ D+ + + T L A K H+ ++ + N++
Sbjct: 839 VQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQF 878
Score = 49.2 bits (112), Expect = 6e-05
Identities = 30/96 (31%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +SRD TAL +A+ G E L+ G+ I+ + + L AS+ GH +V+
Sbjct: 781 PVPSSRD----TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQ 836
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+L+ +GA+++ + K TPL A GH+ V+ ++
Sbjct: 837 LLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV 872
Score = 39.1 bits (87), Expect = 0.068
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 1/88 (1%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEIN-ATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
G T L A+ G V+ L+ G+ +N AT N+ + + A + GH V+ +LL GA+
Sbjct: 95 GRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGAD 154
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAII 578
+ D +T L A GH + V ++
Sbjct: 155 PTHRLKDGSTMLIEAAKGGHTNVVSYLL 182
Score = 36.7 bits (81), Expect = 0.37
Identities = 18/57 (31%), Positives = 32/57 (56%)
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
I++ +TPL +AS+ G++ K LL+ ++ AT TAL A + H + D++
Sbjct: 6 IELGCSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 62
Score = 35.1 bits (77), Expect = 1.1
Identities = 19/58 (32%), Positives = 30/58 (51%)
Query: 803 TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
TPL A+ +++ LL +GAN++A +T L A E G+ A +LL D+
Sbjct: 12 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 69
Score = 34.3 bits (75), Expect = 1.9
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 14/110 (12%)
Query: 526 CSA-LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHS 584
CS L AS GH ++ LL SGAN++ +T L A NGH ++
Sbjct: 10 CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 69
Query: 585 GRKININC-------------ANESGNTPLHLASKWGYEGIARLLIEHGS 621
++ ++ +E G TPL A++ G+ + LI G+
Sbjct: 70 DKQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKGA 119
Score = 34.3 bits (75), Expect = 1.9
Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 802 QTPLHLAAINNKTVVIRLLLDNGANINAIDVAR-NTPLHDASETGNIGAAKILLSYNPDI 860
+TPL AA ++ L+ GAN+N +T + A G++ ++LL++ D
Sbjct: 96 RTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADP 155
Query: 861 TLLNATEKTALAVAKDKVHLTIIDLIDNYAN 891
T T L A H ++ + +Y N
Sbjct: 156 THRLKDGSTMLIEAAKGGHTNVVSYLLDYPN 186
>AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein.
Length = 1486
Score = 79.0 bits (186), Expect = 7e-14
Identities = 47/140 (33%), Positives = 80/140 (57%), Gaps = 5/140 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLH 546
RD G T L +A+ G +VE LL+ G +I A ++ + + L A S G Q V+ +LL
Sbjct: 1117 RDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLA 1176
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GAN +N+ TPL LA + G+++ +K ++ ++G +IN ++ G +PL LA+
Sbjct: 1177 RGANKEHRNVSDYTPLSLAASGGYVNIIKILL----NAGAEINSRTGSKLGISPLMLAAM 1232
Query: 607 WGYEGIARLLIEHGSEPSLQ 626
G+ +LL++ GS+ + Q
Sbjct: 1233 NGHVPAVKLLLDMGSDINAQ 1252
Score = 77.4 bits (182), Expect = 2e-13
Identities = 83/338 (24%), Positives = 146/338 (43%), Gaps = 14/338 (4%)
Query: 521 TDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
T+ N +AL A + GH+ ++ +L+ A I ++ TPL LA GH+ V+ ++
Sbjct: 1084 TESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILL-- 1141
Query: 581 AEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNL 640
G I + + +TPL LA G + + LL+ G+ +N T A +
Sbjct: 1142 --DKGGDIEAQ-SERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASG 1198
Query: 641 RILQVLKSCTPNLFEYIHITSSE--VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN 698
+ ++K E T S+ + + + ++ L SD N +T N
Sbjct: 1199 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN 1258
Query: 699 LKLIERILRAISYGDVKLACFYMNIDYSAF--IAPDKEKSNSLCHPLCECQYCKRKTESC 756
L + + L N+++ A + P E ++ + + +
Sbjct: 1259 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASG-----GYAEVGRVLLDKG 1313
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
D + S+ TAL AA G +FC +LI A+++ RNKK TPL LA+ V
Sbjct: 1314 ADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDV 1373
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
++LL+ GA+++A D + TPL A G++ + L+
Sbjct: 1374 VQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV 1411
Score = 67.7 bits (158), Expect = 2e-10
Identities = 94/417 (22%), Positives = 172/417 (41%), Gaps = 39/417 (9%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L AS G IV+ LL +++N+ +AL YA + G +++ +LL+ GANI
Sbjct: 287 ITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIE 346
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +H G IN + +NE + L LA G+ +
Sbjct: 347 DHNENGHTPLMEAASAGHVEVARVLL---DH-GAGINTH-SNEFKESALTLACYKGHLDM 401
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPNLFEYIHITSSEVKKISC 669
R L+E G++ + TA A ++ + ++L + S + +C
Sbjct: 402 VRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 461
Query: 670 ESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI 729
+ L + ND T ++ A G ++ + + A I
Sbjct: 462 GGHVELAALLIERGANLEEVNDEGYT--------PLMEAAREGHEEMVA--LLLAQGANI 511
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
E++ L C + ++ + T L A++ G E L+
Sbjct: 512 NAQTEETQETALTLACCGGFSEVADFLIKAGADI-ELGCSTPLMEASQEGHLELVKYLLA 570
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN----------AIDVARN---- 835
+ ANV+ T L A N T V +LL GA+++ ID A++
Sbjct: 571 SGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDKQEDMKTILEGIDPAKHQEHE 630
Query: 836 -----TPLHDASETGNIGAAKILLSYNPDITLLNA-TEKTALAVAKDKVHLTIIDLI 886
TPL A+ G++ + L+S ++ A + T +++A HL +++L+
Sbjct: 631 SEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 687
Score = 64.9 bits (151), Expect = 1e-09
Identities = 42/133 (31%), Positives = 72/133 (54%), Gaps = 8/133 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDL--NECSALHYASSRGHQNVLLMLL 545
R GLT L A+ G A + LL+ G+++NA + + +AL A+ +GH +L+
Sbjct: 1286 RAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLI 1345
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
H GA+I+ +N NTPL LA N GH V+ ++ +G +++ A+ TPL A
Sbjct: 1346 HRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLV----QAG--ADVDAADNRKITPLMSAF 1399
Query: 606 KWGYEGIARLLIE 618
+ G+ + + L++
Sbjct: 1400 RKGHVKVVQYLVK 1412
Score = 64.5 bits (150), Expect = 2e-09
Identities = 41/131 (31%), Positives = 70/131 (53%), Gaps = 8/131 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL +A G+A +V LL+ + + + L A+S G+ V +LL GA++N
Sbjct: 1259 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 1318
Query: 554 KNI--DKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ ++T L +A + GH + +I H G I++ N+ GNTPL LAS G+
Sbjct: 1319 PPVPSSRDTALTIAADKGHYKFCELLI----HRGAHIDVR--NKKGNTPLWLASNGGHFD 1372
Query: 612 IARLLIEHGSE 622
+ +LL++ G++
Sbjct: 1373 VVQLLVQAGAD 1383
Score = 61.7 bits (143), Expect = 1e-08
Identities = 93/379 (24%), Positives = 155/379 (40%), Gaps = 31/379 (8%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A S G N + LL G ++N+ + + L LA + G+ + ++ A H+ +
Sbjct: 222 SLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVE 279
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ N+ TPL AS GY I +LL+ H ++ + Q++ TA YA
Sbjct: 280 ---DRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYA---------- 326
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
C + + + +E I +E + ++ A +++ I
Sbjct: 327 -CAGGFVDIVKVLLNEGANIEDHNENGHTPLME--AASAGHVEVARVLLDHGAGINTHSN 383
Query: 708 AISYGDVKLACFYMNIDYSAFI----APDKEKSNSLCHPLCE-CQYCKRKTESC---TDF 759
+ LAC+ ++D F+ A + K++ + L E C + +
Sbjct: 384 EFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGA 443
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN+ + + L AA G E +LI AN+ N + TPL AA ++ L
Sbjct: 444 QVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVAL 503
Query: 820 LLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GANINA + + T L A G A L+ DI L T L A +
Sbjct: 504 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL---GCSTPLMEASQEG 560
Query: 879 HLTIID-LIDNYANKYANT 896
HL ++ L+ + AN +A T
Sbjct: 561 HLELVKYLLASGANVHATT 579
Score = 60.9 bits (141), Expect = 2e-08
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D D + +SN TAL A G +E ++LI A + R+KK TPL LAA V+
Sbjct: 1079 DIDAHT-ESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVV 1137
Query: 818 RLLLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD G +I A + ++TPL A G +LL+ + N ++ T L++A
Sbjct: 1138 EILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAAS 1197
Query: 877 KVHLTIIDLIDN 888
++ II ++ N
Sbjct: 1198 GGYVNIIKILLN 1209
Score = 60.9 bits (141), Expect = 2e-08
Identities = 42/130 (32%), Positives = 67/130 (51%), Gaps = 3/130 (2%)
Query: 760 DVNV-CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
D+N ++N TAL A G E ++L+ +ANV R K TPL AA V R
Sbjct: 1248 DINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGR 1307
Query: 819 LLLDNGANINA--IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD GA++NA + +R+T L A++ G+ ++L+ I + N T L +A +
Sbjct: 1308 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASN 1367
Query: 877 KVHLTIIDLI 886
H ++ L+
Sbjct: 1368 GGHFDVVQLL 1377
Score = 60.5 bits (140), Expect = 3e-08
Identities = 43/149 (28%), Positives = 72/149 (48%), Gaps = 5/149 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINAT-DLNECSALHYASSRGHQNVLLMLLHSGAN 550
G++ L +A+++G V+ LL+MGS+INA + N +AL A +G V+ +LL AN
Sbjct: 1223 GISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKAN 1282
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ + TPL A + G+ + ++ G +N S +T L +A+ G+
Sbjct: 1283 VEHRAKTGLTPLMEAASGGYAEVGRVLL----DKGADVNAPPVPSSRDTALTIAADKGHY 1338
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
LLI G+ ++N T A N
Sbjct: 1339 KFCELLIHRGAHIDVRNKKGNTPLWLASN 1367
Score = 58.0 bits (134), Expect = 1e-07
Identities = 44/135 (32%), Positives = 72/135 (53%), Gaps = 9/135 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNEC--SALHYASSRGHQNVLLMLLH 546
+ +G T L A+ G + LL+ G+ IN T NE SAL A +GH +++ LL
Sbjct: 349 NENGHTPLMEAASAGHVEVARVLLDHGAGIN-THSNEFKESALTLACYKGHLDMVRFLLE 407
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ K + +T L A +GH+ + ++ SG ++N+ +S +PL LA+
Sbjct: 408 AGADQEHKTDEMHTALMEACMDGHVEVARLLL----DSGAQVNMPA--DSFESPLTLAAC 461
Query: 607 WGYEGIARLLIEHGS 621
G+ +A LLIE G+
Sbjct: 462 GGHVELAALLIERGA 476
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/126 (32%), Positives = 62/126 (49%), Gaps = 4/126 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L A G E ++L+ AN RN TPL LAA +I++LL+ GA IN+
Sbjct: 1157 TPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS 1216
Query: 830 IDVAR--NTPLHDASETGNIGAAKILLSYNPDITL-LNATEKTALAVAKDKVHLTIID-L 885
++ +PL A+ G++ A K+LL DI + TAL +A + ++ L
Sbjct: 1217 RTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 1276
Query: 886 IDNYAN 891
+D AN
Sbjct: 1277 LDRKAN 1282
Score = 52.8 bits (121), Expect = 5e-06
Identities = 80/340 (23%), Positives = 133/340 (39%), Gaps = 16/340 (4%)
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
+T L LA GH V +I R I ++ G TPL LA+ G+ G+ +L++
Sbjct: 1089 DTALTLACAGGHEELVSVLI------ARDAKIEHRDKKGFTPLILAATAGHVGVVEILLD 1142
Query: 619 HGSEPSLQNSYHK-TAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G + Q+ K T A + +V+ H S+ +S +
Sbjct: 1143 KGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVN 1202
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ L ++ N S+T L + +L A++ G V + +D + I E +
Sbjct: 1203 IIKILLNAGAEIN--SRTGSKLGISPLMLAAMN-GHVPAV--KLLLDMGSDINAQIETNR 1257
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCD--SNGFTALHYAARYGLDEFCNILIFNRANVN 795
+ L Q D NV G T L AA G E +L+ A+VN
Sbjct: 1258 NTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVN 1317
Query: 796 CRN--KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
T L +AA LL+ GA+I+ + NTPL AS G+ ++L
Sbjct: 1318 APPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLL 1377
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKY 893
+ D+ + + T L A K H+ ++ + N++
Sbjct: 1378 VQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQF 1417
Score = 52.0 bits (119), Expect = 9e-06
Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLHS 547
+ G T L A+ G +V LL G+ INA T+ + +AL A G V L+ +
Sbjct: 482 NDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKA 541
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA+I + +TPL A GHL VK ++ SG N++ +G+T L A +
Sbjct: 542 GADIE---LGCSTPLMEASQEGHLELVKYLL----ASG--ANVHATTATGDTALTYACEN 592
Query: 608 GYEGIARLLIEHGSE 622
G+ +A +L++ G++
Sbjct: 593 GHTDVADVLLQAGAD 607
Score = 49.2 bits (112), Expect = 6e-05
Identities = 30/96 (31%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +SRD TAL +A+ G E L+ G+ I+ + + L AS+ GH +V+
Sbjct: 1320 PVPSSRD----TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQ 1375
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+L+ +GA+++ + K TPL A GH+ V+ ++
Sbjct: 1376 LLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV 1411
Score = 39.1 bits (87), Expect = 0.068
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 1/88 (1%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEIN-ATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
G T L A+ G V+ L+ G+ +N AT N+ + + A + GH V+ +LL GA+
Sbjct: 634 GRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGAD 693
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAII 578
+ D +T L A GH + V ++
Sbjct: 694 PTHRLKDGSTMLIEAAKGGHTNVVSYLL 721
Score = 34.3 bits (75), Expect = 1.9
Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 802 QTPLHLAAINNKTVVIRLLLDNGANINAIDVAR-NTPLHDASETGNIGAAKILLSYNPDI 860
+TPL AA ++ L+ GAN+N +T + A G++ ++LL++ D
Sbjct: 635 RTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADP 694
Query: 861 TLLNATEKTALAVAKDKVHLTIIDLIDNYAN 891
T T L A H ++ + +Y N
Sbjct: 695 THRLKDGSTMLIEAAKGGHTNVVSYLLDYPN 725
>AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens
cDNA FLJ20288 fis, clone HEP04414. ).
Length = 686
Score = 79.0 bits (186), Expect = 7e-14
Identities = 47/140 (33%), Positives = 80/140 (57%), Gaps = 5/140 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLH 546
RD G T L +A+ G +VE LL+ G +I A ++ + + L A S G Q V+ +LL
Sbjct: 295 RDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLA 354
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GAN +N+ TPL LA + G+++ +K ++ ++G +IN ++ G +PL LA+
Sbjct: 355 RGANKEHRNVSDYTPLSLAASGGYVNIIKILL----NAGAEINSRTGSKLGISPLMLAAM 410
Query: 607 WGYEGIARLLIEHGSEPSLQ 626
G+ +LL++ GS+ + Q
Sbjct: 411 NGHVPAVKLLLDMGSDINAQ 430
Score = 77.4 bits (182), Expect = 2e-13
Identities = 83/338 (24%), Positives = 146/338 (43%), Gaps = 14/338 (4%)
Query: 521 TDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
T+ N +AL A + GH+ ++ +L+ A I ++ TPL LA GH+ V+ ++
Sbjct: 262 TESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILL-- 319
Query: 581 AEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNL 640
G I + + +TPL LA G + + LL+ G+ +N T A +
Sbjct: 320 --DKGGDIEAQ-SERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASG 376
Query: 641 RILQVLKSCTPNLFEYIHITSSE--VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN 698
+ ++K E T S+ + + + ++ L SD N +T N
Sbjct: 377 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN 436
Query: 699 LKLIERILRAISYGDVKLACFYMNIDYSAF--IAPDKEKSNSLCHPLCECQYCKRKTESC 756
L + + L N+++ A + P E ++ + + +
Sbjct: 437 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASG-----GYAEVGRVLLDKG 491
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
D + S+ TAL AA G +FC +LI A+++ RNKK TPL LA+ V
Sbjct: 492 ADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDV 551
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
++LL+ GA+++A D + TPL A G++ + L+
Sbjct: 552 VQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV 589
Score = 72.1 bits (169), Expect = 8e-12
Identities = 103/401 (25%), Positives = 167/401 (41%), Gaps = 50/401 (12%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ----- 553
AS G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++++
Sbjct: 3 ASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDKQEDMK 62
Query: 554 ---KNIDK-----------NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNT 599
+ ID TPL A GHL V+ +I G +N AN + +T
Sbjct: 63 TILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLI----SKGANVNRATAN-NDHT 117
Query: 600 PLHLASKWGYEGIARLLIEHGSEPSLQNSYHKT----------------AFDYAHNLRIL 643
+ LA G+ + LL+ HG++P+ + T DY +N +L
Sbjct: 118 VVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYPNN--VL 175
Query: 644 QVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNL--TLKCSDTNDASKTIENLKL 701
V + L S E + S E+ P L +Q T + +N +S+T E L
Sbjct: 176 SVPTTDVSQLPPPSQDQSQEPDRTSQEN-SPALLGVQKAVSTRVPTGSNSSSQTTECLTP 234
Query: 702 IERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKR-KTESCTDFD 760
+ + Y ++D A + + + +L C + + D
Sbjct: 235 ESCSQTTSNVASQSMPPVYPSVDVDAHTESNHDTALTLA---CAGGHEELVSVLIARDAK 291
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQ-TPLHLAAINNKTVVIRL 819
+ D GFT L AA G IL+ ++ ++++ + TPL LA + V+ L
Sbjct: 292 IEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDL 351
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
LL GAN +V+ TPL A+ G + KILL+ +I
Sbjct: 352 LLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI 392
Score = 64.9 bits (151), Expect = 1e-09
Identities = 42/133 (31%), Positives = 72/133 (54%), Gaps = 8/133 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDL--NECSALHYASSRGHQNVLLMLL 545
R GLT L A+ G A + LL+ G+++NA + + +AL A+ +GH +L+
Sbjct: 464 RAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLI 523
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
H GA+I+ +N NTPL LA N GH V+ ++ +G +++ A+ TPL A
Sbjct: 524 HRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLV----QAG--ADVDAADNRKITPLMSAF 577
Query: 606 KWGYEGIARLLIE 618
+ G+ + + L++
Sbjct: 578 RKGHVKVVQYLVK 590
Score = 64.5 bits (150), Expect = 2e-09
Identities = 41/131 (31%), Positives = 70/131 (53%), Gaps = 8/131 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL +A G+A +V LL+ + + + L A+S G+ V +LL GA++N
Sbjct: 437 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 496
Query: 554 KNI--DKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ ++T L +A + GH + +I H G I++ N+ GNTPL LAS G+
Sbjct: 497 PPVPSSRDTALTIAADKGHYKFCELLI----HRGAHIDVR--NKKGNTPLWLASNGGHFD 550
Query: 612 IARLLIEHGSE 622
+ +LL++ G++
Sbjct: 551 VVQLLVQAGAD 561
Score = 60.9 bits (141), Expect = 2e-08
Identities = 42/130 (32%), Positives = 67/130 (51%), Gaps = 3/130 (2%)
Query: 760 DVNV-CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
D+N ++N TAL A G E ++L+ +ANV R K TPL AA V R
Sbjct: 426 DINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGR 485
Query: 819 LLLDNGANINA--IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD GA++NA + +R+T L A++ G+ ++L+ I + N T L +A +
Sbjct: 486 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASN 545
Query: 877 KVHLTIIDLI 886
H ++ L+
Sbjct: 546 GGHFDVVQLL 555
Score = 60.5 bits (140), Expect = 3e-08
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D D + +SN TAL A G +E ++LI A + R+KK TPL LAA V+
Sbjct: 257 DVDAHT-ESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVV 315
Query: 818 RLLLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD G +I A + ++TPL A G +LL+ + N ++ T L++A
Sbjct: 316 EILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAAS 375
Query: 877 KVHLTIIDLIDN 888
++ II ++ N
Sbjct: 376 GGYVNIIKILLN 387
Score = 60.5 bits (140), Expect = 3e-08
Identities = 43/149 (28%), Positives = 72/149 (48%), Gaps = 5/149 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINAT-DLNECSALHYASSRGHQNVLLMLLHSGAN 550
G++ L +A+++G V+ LL+MGS+INA + N +AL A +G V+ +LL AN
Sbjct: 401 GISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKAN 460
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ + TPL A + G+ + ++ G +N S +T L +A+ G+
Sbjct: 461 VEHRAKTGLTPLMEAASGGYAEVGRVLL----DKGADVNAPPVPSSRDTALTIAADKGHY 516
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
LLI G+ ++N T A N
Sbjct: 517 KFCELLIHRGAHIDVRNKKGNTPLWLASN 545
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/126 (32%), Positives = 62/126 (49%), Gaps = 4/126 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L A G E ++L+ AN RN TPL LAA +I++LL+ GA IN+
Sbjct: 335 TPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS 394
Query: 830 IDVAR--NTPLHDASETGNIGAAKILLSYNPDITL-LNATEKTALAVAKDKVHLTIID-L 885
++ +PL A+ G++ A K+LL DI + TAL +A + ++ L
Sbjct: 395 RTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 454
Query: 886 IDNYAN 891
+D AN
Sbjct: 455 LDRKAN 460
Score = 52.8 bits (121), Expect = 5e-06
Identities = 80/340 (23%), Positives = 133/340 (39%), Gaps = 16/340 (4%)
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
+T L LA GH V +I R I ++ G TPL LA+ G+ G+ +L++
Sbjct: 267 DTALTLACAGGHEELVSVLI------ARDAKIEHRDKKGFTPLILAATAGHVGVVEILLD 320
Query: 619 HGSEPSLQNSYHK-TAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G + Q+ K T A + +V+ H S+ +S +
Sbjct: 321 KGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVN 380
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ L ++ N S+T L + +L A++ G V + +D + I E +
Sbjct: 381 IIKILLNAGAEIN--SRTGSKLGISPLMLAAMN-GHVPAV--KLLLDMGSDINAQIETNR 435
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCD--SNGFTALHYAARYGLDEFCNILIFNRANVN 795
+ L Q D NV G T L AA G E +L+ A+VN
Sbjct: 436 NTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVN 495
Query: 796 CRN--KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
T L +AA LL+ GA+I+ + NTPL AS G+ ++L
Sbjct: 496 APPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLL 555
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKY 893
+ D+ + + T L A K H+ ++ + N++
Sbjct: 556 VQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQF 595
Score = 49.2 bits (112), Expect = 6e-05
Identities = 30/96 (31%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +SRD TAL +A+ G E L+ G+ I+ + + L AS+ GH +V+
Sbjct: 498 PVPSSRD----TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQ 553
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+L+ +GA+++ + K TPL A GH+ V+ ++
Sbjct: 554 LLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV 589
Score = 39.1 bits (87), Expect = 0.068
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 1/88 (1%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEIN-ATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
G T L A+ G V+ L+ G+ +N AT N+ + + A + GH V+ +LL GA+
Sbjct: 81 GRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGAD 140
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAII 578
+ D +T L A GH + V ++
Sbjct: 141 PTHRLKDGSTMLIEAAKGGHTNVVSYLL 168
Score = 34.3 bits (75), Expect = 1.9
Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 802 QTPLHLAAINNKTVVIRLLLDNGANINAIDVAR-NTPLHDASETGNIGAAKILLSYNPDI 860
+TPL AA ++ L+ GAN+N +T + A G++ ++LL++ D
Sbjct: 82 RTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADP 141
Query: 861 TLLNATEKTALAVAKDKVHLTIIDLIDNYAN 891
T T L A H ++ + +Y N
Sbjct: 142 THRLKDGSTMLIEAAKGGHTNVVSYLLDYPN 172
>AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein
protein.
Length = 532
Score = 79.0 bits (186), Expect = 7e-14
Identities = 47/140 (33%), Positives = 80/140 (57%), Gaps = 5/140 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLH 546
RD G T L +A+ G +VE LL+ G +I A ++ + + L A S G Q V+ +LL
Sbjct: 161 RDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLA 220
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GAN +N+ TPL LA + G+++ +K ++ ++G +IN ++ G +PL LA+
Sbjct: 221 RGANKEHRNVSDYTPLSLAASGGYVNIIKILL----NAGAEINSRTGSKLGISPLMLAAM 276
Query: 607 WGYEGIARLLIEHGSEPSLQ 626
G+ +LL++ GS+ + Q
Sbjct: 277 NGHVPAVKLLLDMGSDINAQ 296
Score = 77.4 bits (182), Expect = 2e-13
Identities = 83/338 (24%), Positives = 146/338 (43%), Gaps = 14/338 (4%)
Query: 521 TDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
T+ N +AL A + GH+ ++ +L+ A I ++ TPL LA GH+ V+ ++
Sbjct: 128 TESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILL-- 185
Query: 581 AEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNL 640
G I + + +TPL LA G + + LL+ G+ +N T A +
Sbjct: 186 --DKGGDIEAQ-SERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASG 242
Query: 641 RILQVLKSCTPNLFEYIHITSSE--VKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN 698
+ ++K E T S+ + + + ++ L SD N +T N
Sbjct: 243 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN 302
Query: 699 LKLIERILRAISYGDVKLACFYMNIDYSAF--IAPDKEKSNSLCHPLCECQYCKRKTESC 756
L + + L N+++ A + P E ++ + + +
Sbjct: 303 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASG-----GYAEVGRVLLDKG 357
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
D + S+ TAL AA G +FC +LI A+++ RNKK TPL LA+ V
Sbjct: 358 ADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDV 417
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
++LL+ GA+++A D + TPL A G++ + L+
Sbjct: 418 VQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV 455
Score = 64.9 bits (151), Expect = 1e-09
Identities = 42/133 (31%), Positives = 72/133 (54%), Gaps = 8/133 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDL--NECSALHYASSRGHQNVLLMLL 545
R GLT L A+ G A + LL+ G+++NA + + +AL A+ +GH +L+
Sbjct: 330 RAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLI 389
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
H GA+I+ +N NTPL LA N GH V+ ++ +G +++ A+ TPL A
Sbjct: 390 HRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLV----QAG--ADVDAADNRKITPLMSAF 443
Query: 606 KWGYEGIARLLIE 618
+ G+ + + L++
Sbjct: 444 RKGHVKVVQYLVK 456
Score = 64.5 bits (150), Expect = 2e-09
Identities = 41/131 (31%), Positives = 70/131 (53%), Gaps = 8/131 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL +A G+A +V LL+ + + + L A+S G+ V +LL GA++N
Sbjct: 303 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 362
Query: 554 KNI--DKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ ++T L +A + GH + +I H G I++ N+ GNTPL LAS G+
Sbjct: 363 PPVPSSRDTALTIAADKGHYKFCELLI----HRGAHIDVR--NKKGNTPLWLASNGGHFD 416
Query: 612 IARLLIEHGSE 622
+ +LL++ G++
Sbjct: 417 VVQLLVQAGAD 427
Score = 60.9 bits (141), Expect = 2e-08
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
D D + +SN TAL A G +E ++LI A + R+KK TPL LAA V+
Sbjct: 123 DIDAHT-ESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVV 181
Query: 818 RLLLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD G +I A + ++TPL A G +LL+ + N ++ T L++A
Sbjct: 182 EILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAAS 241
Query: 877 KVHLTIIDLIDN 888
++ II ++ N
Sbjct: 242 GGYVNIIKILLN 253
Score = 60.9 bits (141), Expect = 2e-08
Identities = 42/130 (32%), Positives = 67/130 (51%), Gaps = 3/130 (2%)
Query: 760 DVNV-CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
D+N ++N TAL A G E ++L+ +ANV R K TPL AA V R
Sbjct: 292 DINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGR 351
Query: 819 LLLDNGANINA--IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+LLD GA++NA + +R+T L A++ G+ ++L+ I + N T L +A +
Sbjct: 352 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASN 411
Query: 877 KVHLTIIDLI 886
H ++ L+
Sbjct: 412 GGHFDVVQLL 421
Score = 60.5 bits (140), Expect = 3e-08
Identities = 43/149 (28%), Positives = 72/149 (48%), Gaps = 5/149 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINAT-DLNECSALHYASSRGHQNVLLMLLHSGAN 550
G++ L +A+++G V+ LL+MGS+INA + N +AL A +G V+ +LL AN
Sbjct: 267 GISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKAN 326
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ + TPL A + G+ + ++ G +N S +T L +A+ G+
Sbjct: 327 VEHRAKTGLTPLMEAASGGYAEVGRVLL----DKGADVNAPPVPSSRDTALTIAADKGHY 382
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
LLI G+ ++N T A N
Sbjct: 383 KFCELLIHRGAHIDVRNKKGNTPLWLASN 411
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/126 (32%), Positives = 62/126 (49%), Gaps = 4/126 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L A G E ++L+ AN RN TPL LAA +I++LL+ GA IN+
Sbjct: 201 TPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS 260
Query: 830 IDVAR--NTPLHDASETGNIGAAKILLSYNPDITL-LNATEKTALAVAKDKVHLTIID-L 885
++ +PL A+ G++ A K+LL DI + TAL +A + ++ L
Sbjct: 261 RTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 320
Query: 886 IDNYAN 891
+D AN
Sbjct: 321 LDRKAN 326
Score = 52.8 bits (121), Expect = 5e-06
Identities = 80/340 (23%), Positives = 133/340 (39%), Gaps = 16/340 (4%)
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
+T L LA GH V +I R I ++ G TPL LA+ G+ G+ +L++
Sbjct: 133 DTALTLACAGGHEELVSVLI------ARDAKIEHRDKKGFTPLILAATAGHVGVVEILLD 186
Query: 619 HGSEPSLQNSYHK-TAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G + Q+ K T A + +V+ H S+ +S +
Sbjct: 187 KGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVN 246
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ L ++ N S+T L + +L A++ G V + +D + I E +
Sbjct: 247 IIKILLNAGAEIN--SRTGSKLGISPLMLAAMN-GHVPAV--KLLLDMGSDINAQIETNR 301
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCD--SNGFTALHYAARYGLDEFCNILIFNRANVN 795
+ L Q D NV G T L AA G E +L+ A+VN
Sbjct: 302 NTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVN 361
Query: 796 CRN--KKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
T L +AA LL+ GA+I+ + NTPL AS G+ ++L
Sbjct: 362 APPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLL 421
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNYANKY 893
+ D+ + + T L A K H+ ++ + N++
Sbjct: 422 VQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQF 461
Score = 49.2 bits (112), Expect = 6e-05
Identities = 30/96 (31%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P +SRD TAL +A+ G E L+ G+ I+ + + L AS+ GH +V+
Sbjct: 364 PVPSSRD----TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQ 419
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+L+ +GA+++ + K TPL A GH+ V+ ++
Sbjct: 420 LLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV 455
>BC101620-1|AAI01621.1| 1001|Homo sapiens ankyrin repeat domain 35
protein.
Length = 1001
Score = 78.6 bits (185), Expect = 9e-14
Identities = 41/118 (34%), Positives = 66/118 (55%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DSNG + H AA GL E IL+ N A++N +N+ T LHLA I+ + +++LL +G
Sbjct: 51 DSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHG 110
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTI 882
AN +A+D +PLH A+ +G + +L + + +L+ +T L +A H I
Sbjct: 111 ANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAI 168
Score = 69.7 bits (163), Expect = 4e-11
Identities = 46/153 (30%), Positives = 78/153 (50%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ S++ G TALH+A+I + V+ LL+ G+ +A D S LH+A+S G + +L+L
Sbjct: 80 INSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLL 139
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
A ++ + D TPL +A GH ++ G ++N+ N+ + L LA
Sbjct: 140 CDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLL----QRGARVNVTDKND--KSALILA 193
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G +A LL+ HG++ +S A YA
Sbjct: 194 CEKGSAEVAELLLSHGADAGAVDSTGHDALHYA 226
Score = 69.3 bits (162), Expect = 6e-11
Identities = 40/148 (27%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
T DS+G + H+A+ G + LL G++IN+ + + +ALH A+ + +LL
Sbjct: 48 TKLDSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLL 107
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GAN + + + +PLH A ++G C +++ +H + ++ + G TPL +AS
Sbjct: 108 QHGANEDAVDAENRSPLHWAASSG---CASSVLLLCDH---EAFLDVLDNDGRTPLMIAS 161
Query: 606 KWGYEGIARLLIEHGSEPSLQNSYHKTA 633
G+ I L++ G+ ++ + K+A
Sbjct: 162 LGGHAAICSQLLQRGARVNVTDKNDKSA 189
Score = 54.4 bits (125), Expect = 2e-06
Identities = 35/127 (27%), Positives = 64/127 (50%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + +G TALH A + +L+ + AN + + + ++PLH AA + + L
Sbjct: 79 DINSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLL 138
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L D+ A ++ +D TPL AS G+ LL + + + +K+AL +A +K
Sbjct: 139 LCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKSALILACEKGS 198
Query: 880 LTIIDLI 886
+ +L+
Sbjct: 199 AEVAELL 205
Score = 52.8 bits (121), Expect = 5e-06
Identities = 29/79 (36%), Positives = 43/79 (54%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D+ G T L +AS+ G A I LL+ G+ +N TD N+ SAL A +G V +LL G
Sbjct: 150 DNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKSALILACEKGSAEVAELLLSHG 209
Query: 549 ANINQKNIDKNTPLHLAVN 567
A+ + + LH A++
Sbjct: 210 ADAGAVDSTGHDALHYALH 228
Score = 50.0 bits (114), Expect = 4e-05
Identities = 31/110 (28%), Positives = 53/110 (48%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D+ + LH+AA G +L + A ++ + +TPL +A++ + LL G
Sbjct: 117 DAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRG 176
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
A +N D + L A E G+ A++LLS+ D +++T AL A
Sbjct: 177 ARVNVTDKNDKSALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYA 226
Score = 44.4 bits (100), Expect = 0.002
Identities = 28/84 (33%), Positives = 42/84 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D++G T L A+ G C+ L+ A VN +K ++ L LA V LL
Sbjct: 146 LDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKSALILACEKGSAEVAELL 205
Query: 821 LDNGANINAIDVARNTPLHDASET 844
L +GA+ A+D + LH A T
Sbjct: 206 LSHGADAGAVDSTGHDALHYALHT 229
Score = 38.3 bits (85), Expect = 0.12
Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 545 LHSGANINQKNIDKN--TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
L S + +D N +P HLA + G C+ ++ +IN NE G+T LH
Sbjct: 39 LASRKSARPTKLDSNGQSPFHLAASKGLTECLTILL------ANGADINSKNEDGSTALH 92
Query: 603 LASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
LA+ ++L++HG+ ++ +++ +A
Sbjct: 93 LATISCQPQCVKVLLQHGANEDAVDAENRSPLHWA 127
>BC101618-1|AAI01619.1| 1001|Homo sapiens ankyrin repeat domain 35
protein.
Length = 1001
Score = 78.6 bits (185), Expect = 9e-14
Identities = 41/118 (34%), Positives = 66/118 (55%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DSNG + H AA GL E IL+ N A++N +N+ T LHLA I+ + +++LL +G
Sbjct: 51 DSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHG 110
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTI 882
AN +A+D +PLH A+ +G + +L + + +L+ +T L +A H I
Sbjct: 111 ANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAI 168
Score = 69.7 bits (163), Expect = 4e-11
Identities = 46/153 (30%), Positives = 78/153 (50%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ S++ G TALH+A+I + V+ LL+ G+ +A D S LH+A+S G + +L+L
Sbjct: 80 INSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLL 139
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
A ++ + D TPL +A GH ++ G ++N+ N+ + L LA
Sbjct: 140 CDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLL----QRGARVNVTDKND--KSALILA 193
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G +A LL+ HG++ +S A YA
Sbjct: 194 CEKGSAEVAELLLSHGADAGAVDSTGHDALHYA 226
Score = 69.3 bits (162), Expect = 6e-11
Identities = 40/148 (27%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
T DS+G + H+A+ G + LL G++IN+ + + +ALH A+ + +LL
Sbjct: 48 TKLDSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLL 107
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GAN + + + +PLH A ++G C +++ +H + ++ + G TPL +AS
Sbjct: 108 QHGANEDAVDAENRSPLHWAASSG---CASSVLLLCDH---EAFLDVLDNDGRTPLMIAS 161
Query: 606 KWGYEGIARLLIEHGSEPSLQNSYHKTA 633
G+ I L++ G+ ++ + K+A
Sbjct: 162 LGGHAAICSQLLQRGARVNVTDKNDKSA 189
Score = 54.4 bits (125), Expect = 2e-06
Identities = 35/127 (27%), Positives = 64/127 (50%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + +G TALH A + +L+ + AN + + + ++PLH AA + + L
Sbjct: 79 DINSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLL 138
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L D+ A ++ +D TPL AS G+ LL + + + +K+AL +A +K
Sbjct: 139 LCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKSALILACEKGS 198
Query: 880 LTIIDLI 886
+ +L+
Sbjct: 199 AEVAELL 205
Score = 52.8 bits (121), Expect = 5e-06
Identities = 29/79 (36%), Positives = 43/79 (54%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D+ G T L +AS+ G A I LL+ G+ +N TD N+ SAL A +G V +LL G
Sbjct: 150 DNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKSALILACEKGSAEVAELLLSHG 209
Query: 549 ANINQKNIDKNTPLHLAVN 567
A+ + + LH A++
Sbjct: 210 ADAGAVDSTGHDALHYALH 228
Score = 50.0 bits (114), Expect = 4e-05
Identities = 31/110 (28%), Positives = 53/110 (48%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D+ + LH+AA G +L + A ++ + +TPL +A++ + LL G
Sbjct: 117 DAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRG 176
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
A +N D + L A E G+ A++LLS+ D +++T AL A
Sbjct: 177 ARVNVTDKNDKSALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYA 226
Score = 44.4 bits (100), Expect = 0.002
Identities = 28/84 (33%), Positives = 42/84 (50%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D++G T L A+ G C+ L+ A VN +K ++ L LA V LL
Sbjct: 146 LDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKSALILACEKGSAEVAELL 205
Query: 821 LDNGANINAIDVARNTPLHDASET 844
L +GA+ A+D + LH A T
Sbjct: 206 LSHGADAGAVDSTGHDALHYALHT 229
Score = 38.3 bits (85), Expect = 0.12
Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 545 LHSGANINQKNIDKN--TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
L S + +D N +P HLA + G C+ ++ +IN NE G+T LH
Sbjct: 39 LASRKSARPTKLDSNGQSPFHLAASKGLTECLTILL------ANGADINSKNEDGSTALH 92
Query: 603 LASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
LA+ ++L++HG+ ++ +++ +A
Sbjct: 93 LATISCQPQCVKVLLQHGANEDAVDAENRSPLHWA 127
>AK091120-1|BAC03587.1| 1001|Homo sapiens protein ( Homo sapiens
cDNA FLJ33801 fis, clone CTONG2000411. ).
Length = 1001
Score = 78.6 bits (185), Expect = 9e-14
Identities = 41/118 (34%), Positives = 66/118 (55%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DSNG + H AA GL E IL+ N A++N +N+ T LHLA I+ + +++LL +G
Sbjct: 51 DSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHG 110
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTI 882
AN +A+D +PLH A+ +G + +L + + +L+ +T L +A H I
Sbjct: 111 ANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAI 168
Score = 69.3 bits (162), Expect = 6e-11
Identities = 46/153 (30%), Positives = 77/153 (50%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ S++ G TALH+A+I + V+ LL+ G+ +A D S LH+A+S G + +L+L
Sbjct: 80 INSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLL 139
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
A ++ + D TPL +A GH ++ G ++N+ N+ L LA
Sbjct: 140 CDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLL----QRGARVNVTDKND--KAALILA 193
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G +A LL+ HG++ +S A YA
Sbjct: 194 CEKGSAEVAELLLSHGADAGAVDSTGHDALHYA 226
Score = 68.9 bits (161), Expect = 7e-11
Identities = 40/148 (27%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
T DS+G + H+A+ G + LL G++IN+ + + +ALH A+ + +LL
Sbjct: 48 TKLDSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLL 107
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GAN + + + +PLH A ++G C +++ +H + ++ + G TPL +AS
Sbjct: 108 QHGANEDAVDAENRSPLHWAASSG---CASSVLLLCDH---EAFLDVLDNDGRTPLMIAS 161
Query: 606 KWGYEGIARLLIEHGSEPSLQNSYHKTA 633
G+ I L++ G+ ++ + K A
Sbjct: 162 LGGHAAICSQLLQRGARVNVTDKNDKAA 189
Score = 54.0 bits (124), Expect = 2e-06
Identities = 35/127 (27%), Positives = 63/127 (49%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N + +G TALH A + +L+ + AN + + + ++PLH AA + + L
Sbjct: 79 DINSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLL 138
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L D+ A ++ +D TPL AS G+ LL + + + +K AL +A +K
Sbjct: 139 LCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKAALILACEKGS 198
Query: 880 LTIIDLI 886
+ +L+
Sbjct: 199 AEVAELL 205
Score = 51.6 bits (118), Expect = 1e-05
Identities = 28/79 (35%), Positives = 43/79 (54%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D+ G T L +AS+ G A I LL+ G+ +N TD N+ +AL A +G V +LL G
Sbjct: 150 DNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKAALILACEKGSAEVAELLLSHG 209
Query: 549 ANINQKNIDKNTPLHLAVN 567
A+ + + LH A++
Sbjct: 210 ADAGAVDSTGHDALHYALH 228
Score = 49.6 bits (113), Expect = 5e-05
Identities = 31/110 (28%), Positives = 52/110 (47%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D+ + LH+AA G +L + A ++ + +TPL +A++ + LL G
Sbjct: 117 DAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRG 176
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
A +N D L A E G+ A++LLS+ D +++T AL A
Sbjct: 177 ARVNVTDKNDKAALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYA 226
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/84 (33%), Positives = 41/84 (48%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D++G T L A+ G C+ L+ A VN +K + L LA V LL
Sbjct: 146 LDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKAALILACEKGSAEVAELL 205
Query: 821 LDNGANINAIDVARNTPLHDASET 844
L +GA+ A+D + LH A T
Sbjct: 206 LSHGADAGAVDSTGHDALHYALHT 229
Score = 38.3 bits (85), Expect = 0.12
Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 545 LHSGANINQKNIDKN--TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
L S + +D N +P HLA + G C+ ++ +IN NE G+T LH
Sbjct: 39 LASRKSARPTKLDSNGQSPFHLAASKGLTECLTILL------ANGADINSKNEDGSTALH 92
Query: 603 LASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
LA+ ++L++HG+ ++ +++ +A
Sbjct: 93 LATISCQPQCVKVLLQHGANEDAVDAENRSPLHWA 127
>BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 14
protein.
Length = 980
Score = 78.2 bits (184), Expect = 1e-13
Identities = 47/148 (31%), Positives = 70/148 (47%), Gaps = 6/148 (4%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
T DS G TA H+A+ G + ++ G ++ A D SALH A+ H + LL
Sbjct: 47 TKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLL 106
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
S + T LH A G C++A+ EH K IN + GN PL LA
Sbjct: 107 QSKCPAESVDSSGKTALHYAAAQG---CLQAVQILCEH---KSPINLKDLDGNIPLLLAV 160
Query: 606 KWGYEGIARLLIEHGSEPSLQNSYHKTA 633
+ G+ I L++HG++ + +N +TA
Sbjct: 161 QNGHSEICHFLLDHGADVNSRNKSGRTA 188
Score = 76.6 bits (180), Expect = 4e-13
Identities = 49/153 (32%), Positives = 81/153 (52%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T++D+ G +ALH+A+ + + LL+ + D + +ALHYA+++G + +L
Sbjct: 79 VTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQIL 138
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ IN K++D N PL LAV NGH I +F G ++N N+SG T L LA
Sbjct: 139 CEHKSPINLKDLDGNIPLLLAVQNGH----SEICHFLLDHG--ADVNSRNKSGRTALMLA 192
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G LI+ G++ +L +S A Y+
Sbjct: 193 CEIGSSNAVEALIKKGADLNLVDSLGYNALHYS 225
Score = 65.7 bits (153), Expect = 7e-10
Identities = 37/111 (33%), Positives = 61/111 (54%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DS+G TALHYAA G + IL +++ +N ++ PL LA N + + LLD+G
Sbjct: 116 DSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 175
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
A++N+ + + T L A E G+ A + L+ D+ L+++ AL +K
Sbjct: 176 ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSK 226
Score = 57.6 bits (133), Expect = 2e-07
Identities = 40/128 (31%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DS G TA H AA G E ++I + +V ++ + LHLAA N+ IR LL +
Sbjct: 50 DSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSK 109
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
++D + T LH A+ G + A +IL + I L + L +A H I
Sbjct: 110 CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 885 -LIDNYAN 891
L+D+ A+
Sbjct: 170 FLLDHGAD 177
Score = 55.6 bits (128), Expect = 7e-07
Identities = 44/182 (24%), Positives = 77/182 (42%)
Query: 693 SKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRK 752
S T E K +R+L+A+ GD + + ++ D E + + +
Sbjct: 11 SDTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLR 70
Query: 753 TESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINN 812
DV D+ G +ALH AA+ E L+ ++ + +T LH AA
Sbjct: 71 VMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQG 130
Query: 813 KTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALA 872
+++L ++ + IN D+ N PL A + G+ LL + D+ N + +TAL
Sbjct: 131 CLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALM 190
Query: 873 VA 874
+A
Sbjct: 191 LA 192
Score = 55.6 bits (128), Expect = 7e-07
Identities = 31/95 (32%), Positives = 49/95 (51%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+N+ D +G L A + G E C+ L+ + A+VN RNK +T L LA + + L
Sbjct: 145 INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEAL 204
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLS 855
+ GA++N +D LH + + N G +LLS
Sbjct: 205 IKKGADLNLVDSLGYNALHYSKLSENAGIQSLLLS 239
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 7/127 (5%)
Query: 502 HGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNT 560
+G A V +LL + G+ D +A H A+++GH L +++ G ++ ++ ++
Sbjct: 29 NGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHS 88
Query: 561 PLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHG 620
LHLA N H C++ ++ K + SG T LH A+ G ++L EH
Sbjct: 89 ALHLAAKNSHHECIRKLLQ------SKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHK 142
Query: 621 SEPSLQN 627
S +L++
Sbjct: 143 SPINLKD 149
Score = 48.4 bits (110), Expect = 1e-04
Identities = 33/132 (25%), Positives = 61/132 (46%), Gaps = 6/132 (4%)
Query: 516 SEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVK 575
S+ N + N+ L + + V +L GA+ + + + T HLA GH+ C++
Sbjct: 11 SDTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLR 70
Query: 576 AIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFD 635
+I H +++ + +G++ LHLA+K + R L++ +S KTA
Sbjct: 71 VMI---THG---VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALH 124
Query: 636 YAHNLRILQVLK 647
YA LQ ++
Sbjct: 125 YAAAQGCLQAVQ 136
Score = 39.9 bits (89), Expect = 0.039
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHY---ASSRGHQNVL 541
+ SR+ G TAL +A G + VE L++ G+++N D +ALHY + + G Q++L
Sbjct: 178 VNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSENAGIQSLL 237
Query: 542 LMLLHSGANI 551
L + A++
Sbjct: 238 LSKISQDADL 247
Score = 38.3 bits (85), Expect = 0.12
Identities = 26/127 (20%), Positives = 56/127 (44%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N + N L ++ ++L A+ + + +T HLAA +R+
Sbjct: 12 DTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRV 71
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
++ +G ++ A D ++ LH A++ + + LL ++++ KTAL A +
Sbjct: 72 MITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGC 131
Query: 880 LTIIDLI 886
L + ++
Sbjct: 132 LQAVQIL 138
Score = 36.3 bits (80), Expect = 0.48
Identities = 22/91 (24%), Positives = 40/91 (43%)
Query: 789 FNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIG 848
F +++ N NK L + V LL GA+ D T H A+ G++
Sbjct: 8 FRKSDTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVE 67
Query: 849 AAKILLSYNPDITLLNATEKTALAVAKDKVH 879
++++++ D+T + T +AL +A H
Sbjct: 68 CLRVMITHGVDVTAQDTTGHSALHLAAKNSH 98
>AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 14
isoform protein.
Length = 972
Score = 78.2 bits (184), Expect = 1e-13
Identities = 47/148 (31%), Positives = 70/148 (47%), Gaps = 6/148 (4%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
T DS G TA H+A+ G + ++ G ++ A D SALH A+ H + LL
Sbjct: 39 TKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLL 98
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
S + T LH A G C++A+ EH K IN + GN PL LA
Sbjct: 99 QSKCPAESVDSSGKTALHYAAAQG---CLQAVQILCEH---KSPINLKDLDGNIPLLLAV 152
Query: 606 KWGYEGIARLLIEHGSEPSLQNSYHKTA 633
+ G+ I L++HG++ + +N +TA
Sbjct: 153 QNGHSEICHFLLDHGADVNSRNKSGRTA 180
Score = 76.6 bits (180), Expect = 4e-13
Identities = 49/153 (32%), Positives = 81/153 (52%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T++D+ G +ALH+A+ + + LL+ + D + +ALHYA+++G + +L
Sbjct: 71 VTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQIL 130
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ IN K++D N PL LAV NGH I +F G ++N N+SG T L LA
Sbjct: 131 CEHKSPINLKDLDGNIPLLLAVQNGH----SEICHFLLDHG--ADVNSRNKSGRTALMLA 184
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G LI+ G++ +L +S A Y+
Sbjct: 185 CEIGSSNAVEALIKKGADLNLVDSLGYNALHYS 217
Score = 65.7 bits (153), Expect = 7e-10
Identities = 37/111 (33%), Positives = 61/111 (54%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DS+G TALHYAA G + IL +++ +N ++ PL LA N + + LLD+G
Sbjct: 108 DSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 167
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
A++N+ + + T L A E G+ A + L+ D+ L+++ AL +K
Sbjct: 168 ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSK 218
Score = 57.6 bits (133), Expect = 2e-07
Identities = 40/128 (31%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DS G TA H AA G E ++I + +V ++ + LHLAA N+ IR LL +
Sbjct: 42 DSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSK 101
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
++D + T LH A+ G + A +IL + I L + L +A H I
Sbjct: 102 CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICH 161
Query: 885 -LIDNYAN 891
L+D+ A+
Sbjct: 162 FLLDHGAD 169
Score = 56.8 bits (131), Expect = 3e-07
Identities = 44/182 (24%), Positives = 78/182 (42%)
Query: 693 SKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRK 752
+KT E K +R+L+A+ GD + + ++ D E + + +
Sbjct: 3 AKTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLR 62
Query: 753 TESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINN 812
DV D+ G +ALH AA+ E L+ ++ + +T LH AA
Sbjct: 63 VMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQG 122
Query: 813 KTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALA 872
+++L ++ + IN D+ N PL A + G+ LL + D+ N + +TAL
Sbjct: 123 CLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALM 182
Query: 873 VA 874
+A
Sbjct: 183 LA 184
Score = 55.6 bits (128), Expect = 7e-07
Identities = 31/95 (32%), Positives = 49/95 (51%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+N+ D +G L A + G E C+ L+ + A+VN RNK +T L LA + + L
Sbjct: 137 INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEAL 196
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLS 855
+ GA++N +D LH + + N G +LLS
Sbjct: 197 IKKGADLNLVDSLGYNALHYSKLSENAGIQSLLLS 231
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 7/127 (5%)
Query: 502 HGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNT 560
+G A V +LL + G+ D +A H A+++GH L +++ G ++ ++ ++
Sbjct: 21 NGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHS 80
Query: 561 PLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHG 620
LHLA N H C++ ++ K + SG T LH A+ G ++L EH
Sbjct: 81 ALHLAAKNSHHECIRKLLQ------SKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHK 134
Query: 621 SEPSLQN 627
S +L++
Sbjct: 135 SPINLKD 141
Score = 48.0 bits (109), Expect = 1e-04
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 6/134 (4%)
Query: 514 MGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHC 573
M ++ N + N+ L + + V +L GA+ + + + T HLA GH+ C
Sbjct: 1 MEAKTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVEC 60
Query: 574 VKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTA 633
++ +I H +++ + +G++ LHLA+K + R L++ +S KTA
Sbjct: 61 LRVMI---THG---VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTA 114
Query: 634 FDYAHNLRILQVLK 647
YA LQ ++
Sbjct: 115 LHYAAAQGCLQAVQ 128
Score = 39.9 bits (89), Expect = 0.039
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHY---ASSRGHQNVL 541
+ SR+ G TAL +A G + VE L++ G+++N D +ALHY + + G Q++L
Sbjct: 170 VNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSENAGIQSLL 229
Query: 542 LMLLHSGANI 551
L + A++
Sbjct: 230 LSKISQDADL 239
Score = 36.3 bits (80), Expect = 0.48
Identities = 21/95 (22%), Positives = 46/95 (48%)
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A+ + + +T HLAA +R+++ +G ++ A D ++ LH A++ + +
Sbjct: 36 ASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIR 95
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL ++++ KTAL A + L + ++
Sbjct: 96 KLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQIL 130
Score = 33.9 bits (74), Expect = 2.6
Identities = 22/88 (25%), Positives = 37/88 (42%)
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A N NK L + V LL GA+ D T H A+ G++ +
Sbjct: 3 AKTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLR 62
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVH 879
+++++ D+T + T +AL +A H
Sbjct: 63 VMITHGVDVTAQDTTGHSALHLAAKNSH 90
>AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein.
Length = 983
Score = 78.2 bits (184), Expect = 1e-13
Identities = 47/148 (31%), Positives = 70/148 (47%), Gaps = 6/148 (4%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
T DS G TA H+A+ G + ++ G ++ A D SALH A+ H + LL
Sbjct: 50 TKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLL 109
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
S + T LH A G C++A+ EH K IN + GN PL LA
Sbjct: 110 QSKCPAESVDSSGKTALHYAAAQG---CLQAVQILCEH---KSPINLKDLDGNIPLLLAV 163
Query: 606 KWGYEGIARLLIEHGSEPSLQNSYHKTA 633
+ G+ I L++HG++ + +N +TA
Sbjct: 164 QNGHSEICHFLLDHGADVNSRNKSGRTA 191
Score = 76.6 bits (180), Expect = 4e-13
Identities = 49/153 (32%), Positives = 81/153 (52%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T++D+ G +ALH+A+ + + LL+ + D + +ALHYA+++G + +L
Sbjct: 82 VTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQIL 141
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ IN K++D N PL LAV NGH I +F G ++N N+SG T L LA
Sbjct: 142 CEHKSPINLKDLDGNIPLLLAVQNGH----SEICHFLLDHG--ADVNSRNKSGRTALMLA 195
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G LI+ G++ +L +S A Y+
Sbjct: 196 CEIGSSNAVEALIKKGADLNLVDSLGYNALHYS 228
Score = 65.7 bits (153), Expect = 7e-10
Identities = 37/111 (33%), Positives = 61/111 (54%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DS+G TALHYAA G + IL +++ +N ++ PL LA N + + LLD+G
Sbjct: 119 DSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 178
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
A++N+ + + T L A E G+ A + L+ D+ L+++ AL +K
Sbjct: 179 ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSK 229
Score = 57.6 bits (133), Expect = 2e-07
Identities = 40/128 (31%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DS G TA H AA G E ++I + +V ++ + LHLAA N+ IR LL +
Sbjct: 53 DSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSK 112
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
++D + T LH A+ G + A +IL + I L + L +A H I
Sbjct: 113 CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICH 172
Query: 885 -LIDNYAN 891
L+D+ A+
Sbjct: 173 FLLDHGAD 180
Score = 56.4 bits (130), Expect = 4e-07
Identities = 44/181 (24%), Positives = 77/181 (42%)
Query: 694 KTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKT 753
KT E K +R+L+A+ GD + + ++ D E + + +
Sbjct: 15 KTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRV 74
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
DV D+ G +ALH AA+ E L+ ++ + +T LH AA
Sbjct: 75 MITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGC 134
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
+++L ++ + IN D+ N PL A + G+ LL + D+ N + +TAL +
Sbjct: 135 LQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 194
Query: 874 A 874
A
Sbjct: 195 A 195
Score = 55.6 bits (128), Expect = 7e-07
Identities = 31/95 (32%), Positives = 49/95 (51%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+N+ D +G L A + G E C+ L+ + A+VN RNK +T L LA + + L
Sbjct: 148 INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEAL 207
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLS 855
+ GA++N +D LH + + N G +LLS
Sbjct: 208 IKKGADLNLVDSLGYNALHYSKLSENAGIQSLLLS 242
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 7/127 (5%)
Query: 502 HGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNT 560
+G A V +LL + G+ D +A H A+++GH L +++ G ++ ++ ++
Sbjct: 32 NGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHS 91
Query: 561 PLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHG 620
LHLA N H C++ ++ K + SG T LH A+ G ++L EH
Sbjct: 92 ALHLAAKNSHHECIRKLLQ------SKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHK 145
Query: 621 SEPSLQN 627
S +L++
Sbjct: 146 SPINLKD 152
Score = 46.4 bits (105), Expect = 5e-04
Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 6/129 (4%)
Query: 519 NATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
N + N+ L + + V +L GA+ + + + T HLA GH+ C++ +I
Sbjct: 17 NEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMI 76
Query: 579 YFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAH 638
H +++ + +G++ LHLA+K + R L++ +S KTA YA
Sbjct: 77 ---THG---VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAA 130
Query: 639 NLRILQVLK 647
LQ ++
Sbjct: 131 AQGCLQAVQ 139
Score = 39.9 bits (89), Expect = 0.039
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHY---ASSRGHQNVL 541
+ SR+ G TAL +A G + VE L++ G+++N D +ALHY + + G Q++L
Sbjct: 181 VNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSENAGIQSLL 240
Query: 542 LMLLHSGANI 551
L + A++
Sbjct: 241 LSKISQDADL 250
Score = 36.3 bits (80), Expect = 0.48
Identities = 21/95 (22%), Positives = 46/95 (48%)
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A+ + + +T HLAA +R+++ +G ++ A D ++ LH A++ + +
Sbjct: 47 ASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIR 106
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL ++++ KTAL A + L + ++
Sbjct: 107 KLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQIL 141
Score = 32.7 bits (71), Expect = 5.9
Identities = 20/82 (24%), Positives = 35/82 (42%)
Query: 798 NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYN 857
NK L + V LL GA+ D T H A+ G++ ++++++
Sbjct: 20 NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 79
Query: 858 PDITLLNATEKTALAVAKDKVH 879
D+T + T +AL +A H
Sbjct: 80 VDVTAQDTTGHSALHLAAKNSH 101
>AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens
cDNA FLJ34236 fis, clone FCBBF3027199, weakly similar to
ANKYRIN. ).
Length = 505
Score = 78.2 bits (184), Expect = 1e-13
Identities = 46/138 (33%), Positives = 73/138 (52%), Gaps = 4/138 (2%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ SRD+ G T LH A+ + + LL+ +E+NATD +AL A+ G + L
Sbjct: 280 VNSRDTKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFL 339
Query: 545 LHSG-ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L+ G A++ + +KNT LHLA + GH C I+ + G IN N + PLH+
Sbjct: 340 LYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGL---INATNSALQMPLHI 396
Query: 604 ASKWGYEGIARLLIEHGS 621
A++ G + + L+ HG+
Sbjct: 397 AARNGLASVVQALLSHGA 414
Score = 70.9 bits (166), Expect = 2e-11
Identities = 84/342 (24%), Positives = 141/342 (41%), Gaps = 33/342 (9%)
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
+PLHLA NGH +K + AE +N++ + G T L LA++ G +L H
Sbjct: 16 SPLHLAAYNGHCEALKTL---AE---TLVNLDVRDHKGRTALFLATERGSTECVEVLTAH 69
Query: 620 GSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKIS----CESEKPT 675
G+ ++ K +A T +L ++ I S E I+ + P
Sbjct: 70 GASALIKERKRKWTPLHA------AAASGHTDSL--HLLIDSGERADITDVMDVYGQTPL 121
Query: 676 SLKLQNLTLKCSDTN-DASKTIENLKLIERILRAISYGDVKLA--CFYMNIDYSAFIAPD 732
L + N + C + T + L R A+ G V C +D+ AF+
Sbjct: 122 MLAIMNGHVDCVHLLLEKGSTADAADLRGRT--ALHRGAVTGCEDCLAALLDHDAFVLCR 179
Query: 733 KEKSNSLCHPLCECQYCK------RKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNI 786
K + H C + + S D V D +G++ +H+A+ G ++ C
Sbjct: 180 DFKGRTPIHLASACGHTAVLRTLLQAALSTDPLDAGV-DYSGYSPMHWASYTGHED-CLE 237
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDN-GANI-NAIDVARNTPLHDASET 844
L+ + + TPLH A INN+ +LL GA I N+ D TPLH A+
Sbjct: 238 LLLEHSPFSYLEGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDTKGRTPLHAAAFA 297
Query: 845 GNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
N+ ++LL + ++ + T +TAL A + ++ +
Sbjct: 298 DNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFL 339
Score = 67.7 bits (158), Expect = 2e-10
Identities = 44/131 (33%), Positives = 68/131 (51%), Gaps = 2/131 (1%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G T L +A ++G V LLE GS +A DL +ALH + G ++ L LL
Sbjct: 114 DVYGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHD 173
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A + ++ TP+HLA GH ++ ++ A S ++ + SG +P+H AS G
Sbjct: 174 AFVLCRDFKGRTPIHLASACGHTAVLRTLLQ-AALSTDPLDAG-VDYSGYSPMHWASYTG 231
Query: 609 YEGIARLLIEH 619
+E LL+EH
Sbjct: 232 HEDCLELLLEH 242
Score = 65.3 bits (152), Expect = 9e-10
Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 3/118 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILI--FNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLD 822
+ N FT LH A D +L+ VN R+ K +TPLH AA + +R+LL
Sbjct: 249 EGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDTKGRTPLHAAAFADNVSGLRMLLQ 308
Query: 823 NGANINAIDVARNTPLHDASETGNIGAAKILL-SYNPDITLLNATEKTALAVAKDKVH 879
+ A +NA D T L A+E G A + LL D+T+L+ + TAL +A K H
Sbjct: 309 HQAEVNATDHTGRTALMTAAENGQTAAVEFLLYRGKADLTVLDENKNTALHLACSKGH 366
Score = 58.0 bits (134), Expect = 1e-07
Identities = 37/107 (34%), Positives = 56/107 (52%), Gaps = 1/107 (0%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D+ G T LH AA +L+ ++A VN + +T L AA N +T + L
Sbjct: 280 VNSRDTKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFL 339
Query: 821 LDNG-ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNAT 866
L G A++ +D +NT LH A G+ A ++L+ D+ L+NAT
Sbjct: 340 LYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGLINAT 386
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/142 (28%), Positives = 69/142 (48%), Gaps = 7/142 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLL-EMGSEI-NATDLNECSALHYASSRGHQNVLLMLLH 546
+ + T LH A I+ + + E LL +G++I N+ D + LH A+ + + L MLL
Sbjct: 249 EGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDTKGRTPLHAAAFADNVSGLRMLLQ 308
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
A +N + T L A NG V+ ++Y K ++ +E+ NT LHLA
Sbjct: 309 HQAEVNATDHTGRTALMTAAENGQTAAVEFLLYRG-----KADLTVLDENKNTALHLACS 363
Query: 607 WGYEGIARLLIEHGSEPSLQNS 628
G+E A +++ + L N+
Sbjct: 364 KGHEKCALMILAETQDLGLINA 385
Score = 53.2 bits (122), Expect = 4e-06
Identities = 41/143 (28%), Positives = 70/143 (48%), Gaps = 6/143 (4%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGH-QNVLLMLLHSGANI 551
++ LH+A+ +G ++TL E ++ D +AL A+ RG + V ++ H + +
Sbjct: 15 VSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASAL 74
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKINI-NCANESGNTPLHLASKWGYE 610
++ K TPLH A +GH + +I SG + +I + + G TPL LA G+
Sbjct: 75 IKERKRKWTPLHAAAASGHTDSLHLLI----DSGERADITDVMDVYGQTPLMLAIMNGHV 130
Query: 611 GIARLLIEHGSEPSLQNSYHKTA 633
LL+E GS + +TA
Sbjct: 131 DCVHLLLEKGSTADAADLRGRTA 153
Score = 52.8 bits (121), Expect = 5e-06
Identities = 31/82 (37%), Positives = 42/82 (51%), Gaps = 5/82 (6%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRAN----VNCRNKKAQTPLHLAAINNKTV 815
D+ V D N TALH A G E C ++I +N N Q PLH+AA N
Sbjct: 346 DLTVLDENKNTALHLACSKG-HEKCALMILAETQDLGLINATNSALQMPLHIAARNGLAS 404
Query: 816 VIRLLLDNGANINAIDVARNTP 837
V++ LL +GA + A+D +TP
Sbjct: 405 VVQALLSHGATVLAVDEEGHTP 426
Score = 44.4 bits (100), Expect = 0.002
Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 5/123 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFN-RANVNCRNKKAQTPLHLAAINNKTVVIR 818
+VN D G TAL AA G L++ +A++ ++ T LHLA
Sbjct: 312 EVNATDHTGRTALMTAAENGQTAAVEFLLYRGKADLTVLDENKNTALHLACSKGHEKCAL 371
Query: 819 LLLDNGAN---INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKT-ALAVA 874
++L + INA + A PLH A+ G + LLS+ + ++ T ALA A
Sbjct: 372 MILAETQDLGLINATNSALQMPLHIAARNGLASVVQALLSHGATVLAVDEEGHTPALACA 431
Query: 875 KDK 877
+K
Sbjct: 432 PNK 434
Score = 44.0 bits (99), Expect = 0.002
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 7/105 (6%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T + D G TALH ++ G + LL+ + + D + +H AS+ GH VL
Sbjct: 142 TADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRT 201
Query: 544 LLHSGANIN--QKNIDKN--TPLHLAVNNGHLHCVKAIIYFAEHS 584
LL + + + +D + +P+H A GH C++ ++ EHS
Sbjct: 202 LLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLL---EHS 243
Score = 32.7 bits (71), Expect = 5.9
Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 4/98 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSE---INATDLNECSALHYASSRGHQNVL 541
+T D + TALH+A G +L + INAT+ LH A+ G +V+
Sbjct: 347 LTVLDENKNTALHLACSKGHEKCALMILAETQDLGLINATNSALQMPLHIAARNGLASVV 406
Query: 542 LMLLHSGANINQKNIDKNTP-LHLAVNNGHLHCVKAII 578
LL GA + + + +TP L A N C+ I+
Sbjct: 407 QALLSHGATVLAVDEEGHTPALACAPNKDVADCLALIL 444
>AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment
epithelial cell protein protein.
Length = 980
Score = 78.2 bits (184), Expect = 1e-13
Identities = 47/148 (31%), Positives = 70/148 (47%), Gaps = 6/148 (4%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
T DS G TA H+A+ G + ++ G ++ A D SALH A+ H + LL
Sbjct: 47 TKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRRLL 106
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
S + T LH A G C++A+ EH K IN + GN PL LA
Sbjct: 107 QSKCPAESVDSSGKTALHYAAAQG---CLQAVQILCEH---KSPINLKDLDGNIPLLLAV 160
Query: 606 KWGYEGIARLLIEHGSEPSLQNSYHKTA 633
+ G+ I L++HG++ + +N +TA
Sbjct: 161 QNGHSEICHFLLDHGADVNSRNKSGRTA 188
Score = 76.6 bits (180), Expect = 4e-13
Identities = 49/153 (32%), Positives = 81/153 (52%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T++D+ G +ALH+A+ + + LL+ + D + +ALHYA+++G + +L
Sbjct: 79 VTAQDTTGHSALHLAAKNSHHECIRRLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQIL 138
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ IN K++D N PL LAV NGH I +F G ++N N+SG T L LA
Sbjct: 139 CEHKSPINLKDLDGNIPLLLAVQNGH----SEICHFLLDHG--ADVNSRNKSGRTALMLA 192
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G LI+ G++ +L +S A Y+
Sbjct: 193 CEIGSSNAVEALIKKGADLNLVDSLGYNALHYS 225
Score = 65.7 bits (153), Expect = 7e-10
Identities = 37/111 (33%), Positives = 61/111 (54%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DS+G TALHYAA G + IL +++ +N ++ PL LA N + + LLD+G
Sbjct: 116 DSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 175
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
A++N+ + + T L A E G+ A + L+ D+ L+++ AL +K
Sbjct: 176 ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSK 226
Score = 57.6 bits (133), Expect = 2e-07
Identities = 40/128 (31%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DS G TA H AA G E ++I + +V ++ + LHLAA N+ IR LL +
Sbjct: 50 DSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRRLLQSK 109
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
++D + T LH A+ G + A +IL + I L + L +A H I
Sbjct: 110 CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 885 -LIDNYAN 891
L+D+ A+
Sbjct: 170 FLLDHGAD 177
Score = 55.6 bits (128), Expect = 7e-07
Identities = 44/182 (24%), Positives = 77/182 (42%)
Query: 693 SKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRK 752
S T E K +R+L+A+ GD + + ++ D E + + +
Sbjct: 11 SDTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLR 70
Query: 753 TESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINN 812
DV D+ G +ALH AA+ E L+ ++ + +T LH AA
Sbjct: 71 VMITHGVDVTAQDTTGHSALHLAAKNSHHECIRRLLQSKCPAESVDSSGKTALHYAAAQG 130
Query: 813 KTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALA 872
+++L ++ + IN D+ N PL A + G+ LL + D+ N + +TAL
Sbjct: 131 CLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALM 190
Query: 873 VA 874
+A
Sbjct: 191 LA 192
Score = 55.6 bits (128), Expect = 7e-07
Identities = 31/95 (32%), Positives = 49/95 (51%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+N+ D +G L A + G E C+ L+ + A+VN RNK +T L LA + + L
Sbjct: 145 INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEAL 204
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLS 855
+ GA++N +D LH + + N G +LLS
Sbjct: 205 IKKGADLNLVDSLGYNALHYSKLSENAGIQSLLLS 239
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 7/127 (5%)
Query: 502 HGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNT 560
+G A V +LL + G+ D +A H A+++GH L +++ G ++ ++ ++
Sbjct: 29 NGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHS 88
Query: 561 PLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHG 620
LHLA N H C++ ++ K + SG T LH A+ G ++L EH
Sbjct: 89 ALHLAAKNSHHECIRRLLQ------SKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHK 142
Query: 621 SEPSLQN 627
S +L++
Sbjct: 143 SPINLKD 149
Score = 48.4 bits (110), Expect = 1e-04
Identities = 33/132 (25%), Positives = 61/132 (46%), Gaps = 6/132 (4%)
Query: 516 SEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVK 575
S+ N + N+ L + + V +L GA+ + + + T HLA GH+ C++
Sbjct: 11 SDTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLR 70
Query: 576 AIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFD 635
+I H +++ + +G++ LHLA+K + R L++ +S KTA
Sbjct: 71 VMI---THG---VDVTAQDTTGHSALHLAAKNSHHECIRRLLQSKCPAESVDSSGKTALH 124
Query: 636 YAHNLRILQVLK 647
YA LQ ++
Sbjct: 125 YAAAQGCLQAVQ 136
Score = 39.9 bits (89), Expect = 0.039
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHY---ASSRGHQNVL 541
+ SR+ G TAL +A G + VE L++ G+++N D +ALHY + + G Q++L
Sbjct: 178 VNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSENAGIQSLL 237
Query: 542 LMLLHSGANI 551
L + A++
Sbjct: 238 LSKISQDADL 247
Score = 38.3 bits (85), Expect = 0.12
Identities = 26/127 (20%), Positives = 56/127 (44%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N + N L ++ ++L A+ + + +T HLAA +R+
Sbjct: 12 DTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRV 71
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
++ +G ++ A D ++ LH A++ + + LL ++++ KTAL A +
Sbjct: 72 MITHGVDVTAQDTTGHSALHLAAKNSHHECIRRLLQSKCPAESVDSSGKTALHYAAAQGC 131
Query: 880 LTIIDLI 886
L + ++
Sbjct: 132 LQAVQIL 138
Score = 36.3 bits (80), Expect = 0.48
Identities = 22/91 (24%), Positives = 40/91 (43%)
Query: 789 FNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIG 848
F +++ N NK L + V LL GA+ D T H A+ G++
Sbjct: 8 FRKSDTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVE 67
Query: 849 AAKILLSYNPDITLLNATEKTALAVAKDKVH 879
++++++ D+T + T +AL +A H
Sbjct: 68 CLRVMITHGVDVTAQDTTGHSALHLAAKNSH 98
>AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein.
Length = 989
Score = 78.2 bits (184), Expect = 1e-13
Identities = 47/148 (31%), Positives = 70/148 (47%), Gaps = 6/148 (4%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
T DS G TA H+A+ G + ++ G ++ A D SALH A+ H + LL
Sbjct: 56 TKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLL 115
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
S + T LH A G C++A+ EH K IN + GN PL LA
Sbjct: 116 QSKCPAESVDSSGKTALHYAAAQG---CLQAVQILCEH---KSPINLKDLDGNIPLLLAV 169
Query: 606 KWGYEGIARLLIEHGSEPSLQNSYHKTA 633
+ G+ I L++HG++ + +N +TA
Sbjct: 170 QNGHSEICHFLLDHGADVNSRNKSGRTA 197
Score = 76.6 bits (180), Expect = 4e-13
Identities = 49/153 (32%), Positives = 81/153 (52%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T++D+ G +ALH+A+ + + LL+ + D + +ALHYA+++G + +L
Sbjct: 88 VTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQIL 147
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ IN K++D N PL LAV NGH I +F G ++N N+SG T L LA
Sbjct: 148 CEHKSPINLKDLDGNIPLLLAVQNGH----SEICHFLLDHG--ADVNSRNKSGRTALMLA 201
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G LI+ G++ +L +S A Y+
Sbjct: 202 CEIGSSNAVEALIKKGADLNLVDSLGYNALHYS 234
Score = 65.7 bits (153), Expect = 7e-10
Identities = 37/111 (33%), Positives = 61/111 (54%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DS+G TALHYAA G + IL +++ +N ++ PL LA N + + LLD+G
Sbjct: 125 DSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 184
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
A++N+ + + T L A E G+ A + L+ D+ L+++ AL +K
Sbjct: 185 ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSK 235
Score = 57.6 bits (133), Expect = 2e-07
Identities = 40/128 (31%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
DS G TA H AA G E ++I + +V ++ + LHLAA N+ IR LL +
Sbjct: 59 DSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSK 118
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
++D + T LH A+ G + A +IL + I L + L +A H I
Sbjct: 119 CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICH 178
Query: 885 -LIDNYAN 891
L+D+ A+
Sbjct: 179 FLLDHGAD 186
Score = 56.0 bits (129), Expect = 6e-07
Identities = 46/199 (23%), Positives = 84/199 (42%), Gaps = 6/199 (3%)
Query: 676 SLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEK 735
++K + SDTN+ +K + R+L+A+ GD + + ++ D E
Sbjct: 9 NMKSLKAKFRKSDTNEWNKNDD------RLLQAVENGDAEKVASLLGKKGASATKHDSEG 62
Query: 736 SNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVN 795
+ + + DV D+ G +ALH AA+ E L+ ++
Sbjct: 63 KTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAE 122
Query: 796 CRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLS 855
+ +T LH AA +++L ++ + IN D+ N PL A + G+ LL
Sbjct: 123 SVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLD 182
Query: 856 YNPDITLLNATEKTALAVA 874
+ D+ N + +TAL +A
Sbjct: 183 HGADVNSRNKSGRTALMLA 201
Score = 55.6 bits (128), Expect = 7e-07
Identities = 31/95 (32%), Positives = 49/95 (51%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+N+ D +G L A + G E C+ L+ + A+VN RNK +T L LA + + L
Sbjct: 154 INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEAL 213
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLS 855
+ GA++N +D LH + + N G +LLS
Sbjct: 214 IKKGADLNLVDSLGYNALHYSKLSENAGIQSLLLS 248
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 7/127 (5%)
Query: 502 HGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNT 560
+G A V +LL + G+ D +A H A+++GH L +++ G ++ ++ ++
Sbjct: 38 NGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHS 97
Query: 561 PLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHG 620
LHLA N H C++ ++ K + SG T LH A+ G ++L EH
Sbjct: 98 ALHLAAKNSHHECIRKLLQ------SKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHK 151
Query: 621 SEPSLQN 627
S +L++
Sbjct: 152 SPINLKD 158
Score = 48.4 bits (110), Expect = 1e-04
Identities = 33/132 (25%), Positives = 61/132 (46%), Gaps = 6/132 (4%)
Query: 516 SEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVK 575
S+ N + N+ L + + V +L GA+ + + + T HLA GH+ C++
Sbjct: 20 SDTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLR 79
Query: 576 AIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFD 635
+I H +++ + +G++ LHLA+K + R L++ +S KTA
Sbjct: 80 VMI---THG---VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALH 133
Query: 636 YAHNLRILQVLK 647
YA LQ ++
Sbjct: 134 YAAAQGCLQAVQ 145
Score = 39.9 bits (89), Expect = 0.039
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHY---ASSRGHQNVL 541
+ SR+ G TAL +A G + VE L++ G+++N D +ALHY + + G Q++L
Sbjct: 187 VNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSENAGIQSLL 246
Query: 542 LMLLHSGANI 551
L + A++
Sbjct: 247 LSKISQDADL 256
Score = 38.3 bits (85), Expect = 0.12
Identities = 26/127 (20%), Positives = 56/127 (44%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N + N L ++ ++L A+ + + +T HLAA +R+
Sbjct: 21 DTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRV 80
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
++ +G ++ A D ++ LH A++ + + LL ++++ KTAL A +
Sbjct: 81 MITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGC 140
Query: 880 LTIIDLI 886
L + ++
Sbjct: 141 LQAVQIL 147
Score = 36.3 bits (80), Expect = 0.48
Identities = 22/91 (24%), Positives = 40/91 (43%)
Query: 789 FNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIG 848
F +++ N NK L + V LL GA+ D T H A+ G++
Sbjct: 17 FRKSDTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVE 76
Query: 849 AAKILLSYNPDITLLNATEKTALAVAKDKVH 879
++++++ D+T + T +AL +A H
Sbjct: 77 CLRVMITHGVDVTAQDTTGHSALHLAAKNSH 107
>AB033076-1|BAA86564.2| 1777|Homo sapiens KIAA1250 protein protein.
Length = 1777
Score = 78.2 bits (184), Expect = 1e-13
Identities = 88/390 (22%), Positives = 159/390 (40%), Gaps = 18/390 (4%)
Query: 482 CPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVL 541
C + R+ G T L +A+ G IV+ L++ G+ N DL+ +AL AS GH +++
Sbjct: 34 CKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIV 93
Query: 542 LMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
LL G N+ +++ T L A G V+ ++ H N + P+
Sbjct: 94 EELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLL---SHGA---NPSVTGLYSVYPI 147
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
A+ G+ I LL+++G++ + + Y T +A L+ +K + +
Sbjct: 148 IWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGA 207
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN-LKLIERILRAISYGDVKLACFY 720
+ + + + + ++ + + + N K L + + D+ A Y
Sbjct: 208 NSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTY 267
Query: 721 MNIDYSAFIAPDKEKSNSLCHPL--CECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
+NI PD+ L + + + + D D+ D+ TAL++A
Sbjct: 268 VNI-------PDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNK--TALYWAVEK 318
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPL 838
G ++ + K +TPL A V+ LLLD GA ++A+D +TPL
Sbjct: 319 GNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPL 378
Query: 839 HDASETGNIGAAKILLSYNPDITLLNATEK 868
H A + A++LL D LL K
Sbjct: 379 HIAIRGRSRKLAELLLRNPKDGRLLYRPNK 408
Score = 61.7 bits (143), Expect = 1e-08
Identities = 70/293 (23%), Positives = 127/293 (43%), Gaps = 12/293 (4%)
Query: 594 NESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAH---NLRILQVLKSCT 650
NE G TPL +A++ G I + LI++G+ +L++ + TA A ++ I++ L C
Sbjct: 41 NECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCG 100
Query: 651 PNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAIS 710
NL E+ + +C + ++L ++ A+ ++ L + I+ A
Sbjct: 101 VNL-EHRDMGGWTALMWACYKGRTDVVELLL-------SHGANPSVTGLYSVYPIIWAAG 152
Query: 711 YGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFT 770
G + + + + DK + L + K DV+ +N T
Sbjct: 153 RGHADIVHLLLQ-NGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMT 211
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
AL A + G + ++ NVN +K T L +A+ T +++ LLD G +N
Sbjct: 212 ALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIP 271
Query: 831 DVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
D + +T L A G++ + LL DI + KTAL A +K + T++
Sbjct: 272 DRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMV 324
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/123 (32%), Positives = 61/123 (49%), Gaps = 3/123 (2%)
Query: 774 YAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVA 833
+AA G + ++L+ N A VNC +K TPL AA ++ LL GA+++
Sbjct: 149 WAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGAN 208
Query: 834 RNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTII-DLIDNYANK 892
T L A + G + K +L NP++ L + TAL +A + H I+ DL+D A
Sbjct: 209 SMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLD--AGT 266
Query: 893 YAN 895
Y N
Sbjct: 267 YVN 269
Score = 52.4 bits (120), Expect = 7e-06
Identities = 35/124 (28%), Positives = 63/124 (50%), Gaps = 10/124 (8%)
Query: 508 VETLLEMGSEINATDLNEC--SALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLA 565
++ LLE +++ + NEC + L A+ +G+ ++ L+ +GAN N +++D T L A
Sbjct: 27 LKALLEKCKDVD--ERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISA 84
Query: 566 VNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSL 625
GH+H V+ ++ +N+ + G T L A G + LL+ HG+ PS+
Sbjct: 85 SKEGHVHIVEELLKCG------VNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSV 138
Query: 626 QNSY 629
Y
Sbjct: 139 TGLY 142
Score = 51.2 bits (117), Expect = 2e-05
Identities = 35/127 (27%), Positives = 58/127 (45%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ D +G TAL A++ G E L+ VN ++ T L A ++R
Sbjct: 234 NVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRA 293
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL A+I+ T L+ A E GN + +L NPD + +T L A +
Sbjct: 294 LLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRN 353
Query: 880 LTIIDLI 886
+ +++L+
Sbjct: 354 IEVVELL 360
Score = 44.8 bits (101), Expect = 0.001
Identities = 29/94 (30%), Positives = 49/94 (52%)
Query: 793 NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKI 852
+V+ RN+ QTPL +AA +++ L+ NGAN N D+ T L AS+ G++ +
Sbjct: 36 DVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEE 95
Query: 853 LLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL ++ + TAL A K +++L+
Sbjct: 96 LLKCGVNLEHRDMGGWTALMWACYKGRTDVVELL 129
Score = 44.0 bits (99), Expect = 0.002
Identities = 42/175 (24%), Positives = 80/175 (45%), Gaps = 8/175 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L A G IV LL+ ++I+ + +AL++A +G+ ++ +L
Sbjct: 272 DRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCN 331
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
+ D TPL A ++ V+ ++ G K++ ++ G+TPLH+A +
Sbjct: 332 PDTEICTKDGETPLIKATKMRNIEVVELLL----DKGAKVS--AVDKKGDTPLHIAIRGR 385
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
+A LL+ + + L +K A + +N+ KS +F H++ +E
Sbjct: 386 SRKLAELLLRNPKDGRLLYRPNK-AGETPYNIDCSH-QKSILTQIFGARHLSPTE 438
Score = 43.6 bits (98), Expect = 0.003
Identities = 48/154 (31%), Positives = 64/154 (41%), Gaps = 10/154 (6%)
Query: 750 KRKTESCTDFDV-NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
K E C D D N C G T L AA G E LI N AN N + T L A
Sbjct: 28 KALLEKCKDVDERNEC---GQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISA 84
Query: 809 AINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSY--NPDITLLNAT 866
+ ++ LL G N+ D+ T L A G ++LLS+ NP +T L +
Sbjct: 85 SKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYSV 144
Query: 867 EKTALAVAK---DKVHLTIIDLID-NYANKYANT 896
A + D VHL + + N ++KY T
Sbjct: 145 YPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTT 178
Score = 37.1 bits (82), Expect = 0.28
Identities = 29/116 (25%), Positives = 54/116 (46%), Gaps = 3/116 (2%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
R TAL+ A G AT+V +L+ + + + L A+ + V+ +LL
Sbjct: 304 RGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDK 363
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
GA ++ + +TPLH+A+ G + ++ GR + N++G TP ++
Sbjct: 364 GAKVSAVDKKGDTPLHIAI-RGRSRKLAELLLRNPKDGRL--LYRPNKAGETPYNI 416
>BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein.
Length = 399
Score = 77.8 bits (183), Expect = 2e-13
Identities = 46/146 (31%), Positives = 77/146 (52%), Gaps = 6/146 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +++ GLTALH A+ V+ LL GS +NA S LHYA+ G ++V +L
Sbjct: 127 LEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVL 186
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+H+G N + +PLHLAV + V+ +I ++N + TPLHLA
Sbjct: 187 IHAGGCANVVDHQGASPLHLAVRHNFPALVRLLI------NSDSDVNAVDNRQQTPLHLA 240
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYH 630
++ ++ IA +L+ G + +L++ H
Sbjct: 241 AEHAWQDIADMLLIAGVDLNLRDKDH 266
Score = 70.5 bits (165), Expect = 2e-11
Identities = 42/132 (31%), Positives = 67/132 (50%), Gaps = 6/132 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G TA H A+ HG+ ++ L+ G + N D +ALH A+ RGH VL L+ G
Sbjct: 65 DKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIG 124
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ ++N + T LH A H CV+ ++ +G +N + + LH A+ G
Sbjct: 125 LDLEEQNAEGLTALHSAAGGSHPDCVQLLL----RAGS--TVNALTQKNLSCLHYAALSG 178
Query: 609 YEGIARLLIEHG 620
E ++R+LI G
Sbjct: 179 SEDVSRVLIHAG 190
Score = 68.1 bits (159), Expect = 1e-10
Identities = 40/150 (26%), Positives = 76/150 (50%), Gaps = 6/150 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G TALH+A+ G +++ L+++G ++ + +ALH A+ H + + +LL +
Sbjct: 97 KDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRA 156
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+ +N + LH A +G + +I H+G N+ + G +PLHLA +
Sbjct: 157 GSTVNALTQKNLSCLHYAALSGSEDVSRVLI----HAGGCANV--VDHQGASPLHLAVRH 210
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ + RLLI S+ + ++ +T A
Sbjct: 211 NFPALVRLLINSDSDVNAVDNRQQTPLHLA 240
Score = 64.1 bits (149), Expect = 2e-09
Identities = 34/102 (33%), Positives = 55/102 (53%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN + LHYAA G ++ +LI N + + +PLHLA +N ++RLL
Sbjct: 160 VNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLL 219
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITL 862
+++ +++NA+D + TPLH A+E A +LL D+ L
Sbjct: 220 INSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNL 261
Score = 58.0 bits (134), Expect = 1e-07
Identities = 38/147 (25%), Positives = 73/147 (49%), Gaps = 8/147 (5%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+ AL +++ G I++ L+ G++I+ + + LH A+ +GH VL ++ ++
Sbjct: 1 MNALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVA 60
Query: 553 QKNIDK--NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++DK T H A +G L + ++ G + N ++ GNT LHLA+ G+
Sbjct: 61 LDHVDKLGRTAFHRAAEHGQLDALDFLV------GSGCDHNVKDKEGNTALHLAAGRGHM 114
Query: 611 GIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ + L++ G + QN+ TA A
Sbjct: 115 AVLQRLVDIGLDLEEQNAEGLTALHSA 141
Score = 53.2 bits (122), Expect = 4e-06
Identities = 33/127 (25%), Positives = 62/127 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ ++ G TALH AA + +L+ + VN +K + LH AA++ V R+
Sbjct: 126 DLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 185
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ G N +D +PLH A ++L++ + D+ ++ ++T L +A +
Sbjct: 186 LIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAW 245
Query: 880 LTIIDLI 886
I D++
Sbjct: 246 QDIADML 252
Score = 49.2 bits (112), Expect = 6e-05
Identities = 32/121 (26%), Positives = 55/121 (45%)
Query: 754 ESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
E D ++ D G TA H AA +G + + L+ + + N ++K+ T LHLAA
Sbjct: 54 EDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGH 113
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
V++ L+D G ++ + T LH A+ + ++LL + L + L
Sbjct: 114 MAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHY 173
Query: 874 A 874
A
Sbjct: 174 A 174
Score = 46.8 bits (106), Expect = 3e-04
Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDN--GANIN 828
AL +A +G IL+ + A ++C +K T LH AA V+ ++++ ++
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 829 AIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID-LID 887
+D T H A+E G + A L+ D + + TAL +A + H+ ++ L+D
Sbjct: 63 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 122
Score = 46.8 bits (106), Expect = 3e-04
Identities = 25/70 (35%), Positives = 38/70 (54%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
NV D G + LH A R+ +LI + ++VN + + QTPLHLAA + + +LL
Sbjct: 194 NVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLL 253
Query: 822 DNGANINAID 831
G ++N D
Sbjct: 254 IAGVDLNLRD 263
Score = 46.0 bits (104), Expect = 6e-04
Identities = 23/85 (27%), Positives = 41/85 (48%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ + L+ LH A++ G + L+ G N D S LH A ++ +
Sbjct: 159 TVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRL 218
Query: 544 LLHSGANINQKNIDKNTPLHLAVNN 568
L++S +++N + + TPLHLA +
Sbjct: 219 LINSDSDVNAVDNRQQTPLHLAAEH 243
Score = 42.3 bits (95), Expect = 0.007
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 3/126 (2%)
Query: 764 CDS-NGFTALHYAARYGLDEFCNILIFNRANVNCRN--KKAQTPLHLAAINNKTVVIRLL 820
C+S +G T LH AA+ G ++ + +V + K +T H AA + + + L
Sbjct: 28 CESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFL 87
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ +G + N D NT LH A+ G++ + L+ D+ NA TAL A H
Sbjct: 88 VGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHP 147
Query: 881 TIIDLI 886
+ L+
Sbjct: 148 DCVQLL 153
>AL133620-1|CAB63746.1| 1031|Homo sapiens hypothetical protein
protein.
Length = 1031
Score = 77.8 bits (183), Expect = 2e-13
Identities = 89/390 (22%), Positives = 161/390 (41%), Gaps = 17/390 (4%)
Query: 482 CPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVL 541
C + R+ G T L +A+ G IV+ L++ G+ N DL+ +AL AS GH +++
Sbjct: 28 CKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIV 87
Query: 542 LMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
LL G N+ +++ T L A G V+ ++ H G ++ S P+
Sbjct: 88 EELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLL---SH-GANPSVTGLQYS-VYPI 142
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITS 661
A+ G+ I LL+++G++ + + Y T +A L+ +K + +
Sbjct: 143 IWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGA 202
Query: 662 SEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN-LKLIERILRAISYGDVKLACFY 720
+ + + + + ++ + + + N K L + + D+ A Y
Sbjct: 203 NSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTY 262
Query: 721 MNIDYSAFIAPDKEKSNSLCHPL--CECQYCKRKTESCTDFDVNVCDSNGFTALHYAARY 778
+NI PD+ L + + + + D D+ D+ TAL++A
Sbjct: 263 VNI-------PDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNK--TALYWAVEK 313
Query: 779 GLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPL 838
G ++ + K +TPL A V+ LLLD GA ++A+D +TPL
Sbjct: 314 GNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPL 373
Query: 839 HDASETGNIGAAKILLSYNPDITLLNATEK 868
H A + A++LL D LL K
Sbjct: 374 HIAIRGRSRKLAELLLRNPKDGRLLYRPNK 403
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/123 (32%), Positives = 61/123 (49%), Gaps = 3/123 (2%)
Query: 774 YAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVA 833
+AA G + ++L+ N A VNC +K TPL AA ++ LL GA+++
Sbjct: 144 WAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGAN 203
Query: 834 RNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTII-DLIDNYANK 892
T L A + G + K +L NP++ L + TAL +A + H I+ DL+D A
Sbjct: 204 SMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLD--AGT 261
Query: 893 YAN 895
Y N
Sbjct: 262 YVN 264
Score = 56.4 bits (130), Expect = 4e-07
Identities = 37/124 (29%), Positives = 60/124 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DV+ +N TAL A + G + ++ NVN +K T L +A+ T +++
Sbjct: 196 DVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQD 255
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LLD G +N D + +T L A G++ + LL DI + KTAL A +K +
Sbjct: 256 LLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGN 315
Query: 880 LTII 883
T++
Sbjct: 316 ATMV 319
Score = 54.8 bits (126), Expect = 1e-06
Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 1/111 (0%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQT-PLHLAAINNKTVVIRLLLDN 823
D G+TAL +A G + +L+ + AN + + P+ AA ++ LLL N
Sbjct: 101 DMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLQYSVYPIIWAAGRGHADIVHLLLQN 160
Query: 824 GANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
GA +N D TPL A+ G++ K LL+ D+ A TAL VA
Sbjct: 161 GAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVA 211
Score = 51.2 bits (117), Expect = 2e-05
Identities = 35/127 (27%), Positives = 58/127 (45%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN+ D +G TAL A++ G E L+ VN ++ T L A ++R
Sbjct: 229 NVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRA 288
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL A+I+ T L+ A E GN + +L NPD + +T L A +
Sbjct: 289 LLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRN 348
Query: 880 LTIIDLI 886
+ +++L+
Sbjct: 349 IEVVELL 355
Score = 50.8 bits (116), Expect = 2e-05
Identities = 34/120 (28%), Positives = 62/120 (51%), Gaps = 10/120 (8%)
Query: 508 VETLLEMGSEINATDLNEC--SALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLA 565
++ LLE +++ + NEC + L A+ +G+ ++ L+ +GAN N +++D T L A
Sbjct: 21 LKALLEKCKDVD--ERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISA 78
Query: 566 VNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSL 625
GH+H V+ ++ +N+ + G T L A G + LL+ HG+ PS+
Sbjct: 79 SKEGHVHIVEELLKCG------VNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSV 132
Score = 44.8 bits (101), Expect = 0.001
Identities = 29/94 (30%), Positives = 49/94 (52%)
Query: 793 NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKI 852
+V+ RN+ QTPL +AA +++ L+ NGAN N D+ T L AS+ G++ +
Sbjct: 30 DVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEE 89
Query: 853 LLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LL ++ + TAL A K +++L+
Sbjct: 90 LLKCGVNLEHRDMGGWTALMWACYKGRTDVVELL 123
Score = 44.0 bits (99), Expect = 0.002
Identities = 42/175 (24%), Positives = 80/175 (45%), Gaps = 8/175 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G T L A G IV LL+ ++I+ + +AL++A +G+ ++ +L
Sbjct: 267 DRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCN 326
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
+ D TPL A ++ V+ ++ G K++ ++ G+TPLH+A +
Sbjct: 327 PDTEICTKDGETPLIKATKMRNIEVVELLL----DKGAKVS--AVDKKGDTPLHIAIRGR 380
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
+A LL+ + + L +K A + +N+ KS +F H++ +E
Sbjct: 381 SRKLAELLLRNPKDGRLLYRPNK-AGETPYNIDCSH-QKSILTQIFGARHLSPTE 433
Score = 41.5 bits (93), Expect = 0.013
Identities = 48/155 (30%), Positives = 64/155 (41%), Gaps = 11/155 (7%)
Query: 750 KRKTESCTDFDV-NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA 808
K E C D D N C G T L AA G E LI N AN N + T L A
Sbjct: 22 KALLEKCKDVDERNEC---GQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISA 78
Query: 809 AINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSY--NPDITLLNAT 866
+ ++ LL G N+ D+ T L A G ++LLS+ NP +T L +
Sbjct: 79 SKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLQYS 138
Query: 867 EKTALAVA----KDKVHLTIIDLID-NYANKYANT 896
+ A D VHL + + N ++KY T
Sbjct: 139 VYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTT 173
Score = 37.1 bits (82), Expect = 0.28
Identities = 29/116 (25%), Positives = 54/116 (46%), Gaps = 3/116 (2%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
R TAL+ A G AT+V +L+ + + + L A+ + V+ +LL
Sbjct: 299 RGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDK 358
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
GA ++ + +TPLH+A+ G + ++ GR + N++G TP ++
Sbjct: 359 GAKVSAVDKKGDTPLHIAI-RGRSRKLAELLLRNPKDGRL--LYRPNKAGETPYNI 411
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/152 (33%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
++ G T L AS G IVE L E G+++NA D + ALH A R V+ LL
Sbjct: 508 KNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQ 567
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G ++ ++ NTPLH+A +G++ V A+ N++ +N+ G TPLHLA+
Sbjct: 568 GCFVDYQDRHGNTPLHVACKDGNMPIVVAL------CEANCNLDISNKYGRTPLHLAANN 621
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
G + R L G+ + KTA D A +
Sbjct: 622 GILDVVRYLCLMGASVEALTTDGKTAEDLARS 653
Score = 74.1 bits (174), Expect = 2e-12
Identities = 48/161 (29%), Positives = 77/161 (47%), Gaps = 6/161 (3%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
SR T LH A+ HG ++ + L E G +N + + L AS+RG+ +++ L
Sbjct: 474 SRTKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAE 533
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA++N + D + LHLAV + +K ++ + ++ + GNTPLH+A K
Sbjct: 534 HGADLNACDKDGHIALHLAVRRCQMEVIKTLL------SQGCFVDYQDRHGNTPLHVACK 587
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G I L E + N Y +T A N IL V++
Sbjct: 588 DGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVR 628
Score = 64.5 bits (150), Expect = 2e-09
Identities = 43/136 (31%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G A++ A+ HG ++ L E ++ D + ALH A+ GH +V + +
Sbjct: 408 QDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQVTCAA 467
Query: 548 GANIN-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
A I + ++ TPLH A +G+ KA+ +G N+N N G TPL AS
Sbjct: 468 SAQIPISRTKEEETPLHCAAWHGYYSVAKALC----EAG--CNVNIKNREGETPLLTASA 521
Query: 607 WGYEGIARLLIEHGSE 622
GY I L EHG++
Sbjct: 522 RGYHDIVECLAEHGAD 537
Score = 62.1 bits (144), Expect = 8e-09
Identities = 68/301 (22%), Positives = 116/301 (38%), Gaps = 11/301 (3%)
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
++N N+ G PL +A+ G I +LLI+ GS +Q+ A +A + LK
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKF 430
Query: 649 CTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRA 708
+ N + + + + + + +T S S+T E +
Sbjct: 431 LSENKCP-LDVKDKSGEMALHVAARYGHADVAQVTCAASAQIPISRTKEEETPLHCAAWH 489
Query: 709 ISYGDVKLAC---FYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCD 765
Y K C +NI P S H + EC + D+N CD
Sbjct: 490 GYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECL-------AEHGADLNACD 542
Query: 766 SNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGA 825
+G ALH A R E L+ V+ +++ TPLH+A + ++ L +
Sbjct: 543 KDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANC 602
Query: 826 NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDL 885
N++ + TPLH A+ G + + L + L KTA +A+ + H + L
Sbjct: 603 NLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGL 662
Query: 886 I 886
+
Sbjct: 663 L 663
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 5/144 (3%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ HG L +A+ G I++ L++ GS I+ D +A+++A+ GH + L L +
Sbjct: 376 NKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENK 435
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ K+ LH+A GH + + +I I+ E TPLH A+ G
Sbjct: 436 CPLDVKDKSGEMALHVAARYGHADVAQVTC----AASAQIPISRTKEE-ETPLHCAAWHG 490
Query: 609 YEGIARLLIEHGSEPSLQNSYHKT 632
Y +A+ L E G +++N +T
Sbjct: 491 YYSVAKALCEAGCNVNIKNREGET 514
Score = 48.8 bits (111), Expect = 8e-05
Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 6/133 (4%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T LH AA +G L NVN +N++ +TPL A+ ++ L ++GA++NA
Sbjct: 481 TPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNA 540
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA-KDKVHLTIIDLID- 887
D + LH A + K LLS + + T L VA KD ++ L +
Sbjct: 541 CDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEA 600
Query: 888 ----NYANKYANT 896
+ +NKY T
Sbjct: 601 NCNLDISNKYGRT 613
Score = 46.0 bits (104), Expect = 6e-04
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 1/145 (0%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D HG T LHVA G IV L E ++ ++ + LH A++ G +V+ L
Sbjct: 574 QDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLM 633
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK- 606
GA++ D T LA + H H + + + R + I + N + K
Sbjct: 634 GASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKDTHRGLFIQQLRPTQNLQPRIKLKL 693
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHK 631
+G+ G + + + L S+ +
Sbjct: 694 FGHSGSGKTTLVESLKCGLLRSFFR 718
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/152 (33%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
++ G T L AS G IVE L E G+++NA D + ALH A R V+ LL
Sbjct: 507 KNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQ 566
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G ++ ++ NTPLH+A +G++ V A+ N++ +N+ G TPLHLA+
Sbjct: 567 GCFVDYQDRHGNTPLHVACKDGNMPIVVAL------CEANCNLDISNKYGRTPLHLAANN 620
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
G + R L G+ + KTA D A +
Sbjct: 621 GILDVVRYLCLMGASVEALTTDGKTAEDLARS 652
Score = 73.7 bits (173), Expect = 3e-12
Identities = 47/160 (29%), Positives = 77/160 (48%), Gaps = 6/160 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D T LH A+ HG ++ + L E G +N + + L AS+RG+ +++ L
Sbjct: 474 QDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEH 533
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA++N + D + LHLAV + +K ++ + ++ + GNTPLH+A K
Sbjct: 534 GADLNACDKDGHIALHLAVRRCQMEVIKTLL------SQGCFVDYQDRHGNTPLHVACKD 587
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G I L E + N Y +T A N IL V++
Sbjct: 588 GNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVR 627
Score = 73.3 bits (172), Expect = 3e-12
Identities = 45/135 (33%), Positives = 69/135 (51%), Gaps = 6/135 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G A++ A+ HG ++ L E ++ D + ALH A+ GH +V +L
Sbjct: 408 QDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSF 467
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+N N ++ ++ TPLH A +G+ KA+ +G N+N N G TPL AS
Sbjct: 468 GSNPNIQDKEEETPLHCAAWHGYYSVAKALC----EAG--CNVNIKNREGETPLLTASAR 521
Query: 608 GYEGIARLLIEHGSE 622
GY I L EHG++
Sbjct: 522 GYHDIVECLAEHGAD 536
Score = 72.9 bits (171), Expect = 5e-12
Identities = 48/156 (30%), Positives = 75/156 (48%), Gaps = 7/156 (4%)
Query: 482 CPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVL 541
CP + +D G ALHVA+ +G A + + L GS N D E + LH A+ G+ +V
Sbjct: 436 CP-LDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVA 494
Query: 542 LMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
L +G N+N KN + TPL A G+ V+ + AEH ++N ++ G+ L
Sbjct: 495 KALCEAGCNVNIKNREGETPLLTASARGYHDIVECL---AEHGA---DLNACDKDGHIAL 548
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
HLA + + + L+ G Q+ + T A
Sbjct: 549 HLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA 584
Score = 65.3 bits (152), Expect = 9e-10
Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ HG L +A+ G I++ L++ GS I+ D +A+++A+ GH + L L +
Sbjct: 376 NKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENK 435
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ K+ LH+A GH + + F N N ++ TPLH A+ G
Sbjct: 436 CPLDVKDKSGEMALHVAARYGHADVAQLLCSFGS------NPNIQDKEEETPLHCAAWHG 489
Query: 609 YEGIARLLIEHGSEPSLQNSYHKT 632
Y +A+ L E G +++N +T
Sbjct: 490 YYSVAKALCEAGCNVNIKNREGET 513
Score = 62.9 bits (146), Expect = 5e-09
Identities = 38/123 (30%), Positives = 61/123 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D +G ALH AARYG + +L +N N ++K+ +TPLH AA + V + L
Sbjct: 438 LDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKAL 497
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ G N+N + TPL AS G + L + D+ + AL +A + +
Sbjct: 498 CEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQM 557
Query: 881 TII 883
+I
Sbjct: 558 EVI 560
Score = 60.5 bits (140), Expect = 3e-08
Identities = 36/126 (28%), Positives = 62/126 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D G A+++AAR+G + L N+ ++ ++K + LH+AA V +LL
Sbjct: 405 IDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLL 464
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
G+N N D TPLH A+ G AK L ++ + N +T L A + +
Sbjct: 465 CSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYH 524
Query: 881 TIIDLI 886
I++ +
Sbjct: 525 DIVECL 530
Score = 60.5 bits (140), Expect = 3e-08
Identities = 34/127 (26%), Positives = 58/127 (45%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N CD +G ALH A R E L+ V+ +++ TPLH+A + ++
Sbjct: 536 DLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA 595
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L + N++ + TPLH A+ G + + L + L KTA +A+ + H
Sbjct: 596 LCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQH 655
Query: 880 LTIIDLI 886
+ L+
Sbjct: 656 EHVAGLL 662
Score = 55.2 bits (127), Expect = 1e-06
Identities = 42/152 (27%), Positives = 66/152 (43%)
Query: 732 DKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
DKE+ L Y K +VN+ + G T L A+ G + L +
Sbjct: 475 DKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHG 534
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++N +K LHLA + VI+ LL G ++ D NTPLH A + GN+
Sbjct: 535 ADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV 594
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
L N ++ + N +T L +A + L ++
Sbjct: 595 ALCEANCNLDISNKYGRTPLHLAANNGILDVV 626
Score = 51.6 bits (118), Expect = 1e-05
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 6/141 (4%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ D T LH AA +G L NVN +N++ +TPL A+ ++ L
Sbjct: 472 NIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA-KDKVHL 880
++GA++NA D + LH A + K LLS + + T L VA KD
Sbjct: 532 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 591
Query: 881 TIIDLID-----NYANKYANT 896
++ L + + +NKY T
Sbjct: 592 IVVALCEANCNLDISNKYGRT 612
Score = 46.0 bits (104), Expect = 6e-04
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 1/145 (0%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D HG T LHVA G IV L E ++ ++ + LH A++ G +V+ L
Sbjct: 573 QDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLM 632
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK- 606
GA++ D T LA + H H + + + R + I + N + K
Sbjct: 633 GASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKDTHRGLFIQQLRPTQNLQPRIKLKL 692
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHK 631
+G+ G + + + L S+ +
Sbjct: 693 FGHSGSGKTTLVESLKCGLLRSFFR 717
Score = 44.8 bits (101), Expect = 0.001
Identities = 34/101 (33%), Positives = 47/101 (46%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
A DK+ +L + CQ KT V+ D +G T LH A + G L
Sbjct: 539 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
N++ NK +TPLHLAA N V+R L GA++ A+
Sbjct: 599 ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEAL 639
Score = 44.4 bits (100), Expect = 0.002
Identities = 28/120 (23%), Positives = 58/120 (48%)
Query: 755 SCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
S +++DVN + +G L AA G + +LI + ++ ++K ++ AA +
Sbjct: 366 SLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHV 425
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
++ L +N ++ D + LH A+ G+ A++L S+ + + + E+T L A
Sbjct: 426 DTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCA 485
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/152 (33%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
++ G T L AS G IVE L E G+++NA D + ALH A R V+ LL
Sbjct: 507 KNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQ 566
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G ++ ++ NTPLH+A +G++ V A+ N++ +N+ G TPLHLA+
Sbjct: 567 GCFVDYQDRHGNTPLHVACKDGNMPIVVAL------CEANCNLDISNKYGRTPLHLAANN 620
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
G + R L G+ + KTA D A +
Sbjct: 621 GILDVVRYLCLMGASVEALTTDGKTAEDLARS 652
Score = 73.7 bits (173), Expect = 3e-12
Identities = 47/160 (29%), Positives = 77/160 (48%), Gaps = 6/160 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D T LH A+ HG ++ + L E G +N + + L AS+RG+ +++ L
Sbjct: 474 QDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEH 533
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA++N + D + LHLAV + +K ++ + ++ + GNTPLH+A K
Sbjct: 534 GADLNACDKDGHIALHLAVRRCQMEVIKTLL------SQGCFVDYQDRHGNTPLHVACKD 587
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G I L E + N Y +T A N IL V++
Sbjct: 588 GNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVR 627
Score = 73.3 bits (172), Expect = 3e-12
Identities = 45/135 (33%), Positives = 69/135 (51%), Gaps = 6/135 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G A++ A+ HG ++ L E ++ D + ALH A+ GH +V +L
Sbjct: 408 QDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSF 467
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+N N ++ ++ TPLH A +G+ KA+ +G N+N N G TPL AS
Sbjct: 468 GSNPNIQDKEEETPLHCAAWHGYYSVAKALC----EAG--CNVNIKNREGETPLLTASAR 521
Query: 608 GYEGIARLLIEHGSE 622
GY I L EHG++
Sbjct: 522 GYHDIVECLAEHGAD 536
Score = 72.9 bits (171), Expect = 5e-12
Identities = 48/156 (30%), Positives = 75/156 (48%), Gaps = 7/156 (4%)
Query: 482 CPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVL 541
CP + +D G ALHVA+ +G A + + L GS N D E + LH A+ G+ +V
Sbjct: 436 CP-LDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVA 494
Query: 542 LMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
L +G N+N KN + TPL A G+ V+ + AEH ++N ++ G+ L
Sbjct: 495 KALCEAGCNVNIKNREGETPLLTASARGYHDIVECL---AEHGA---DLNACDKDGHIAL 548
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
HLA + + + L+ G Q+ + T A
Sbjct: 549 HLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA 584
Score = 65.3 bits (152), Expect = 9e-10
Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ HG L +A+ G I++ L++ GS I+ D +A+++A+ GH + L L +
Sbjct: 376 NKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENK 435
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ K+ LH+A GH + + F N N ++ TPLH A+ G
Sbjct: 436 CPLDVKDKSGEMALHVAARYGHADVAQLLCSFGS------NPNIQDKEEETPLHCAAWHG 489
Query: 609 YEGIARLLIEHGSEPSLQNSYHKT 632
Y +A+ L E G +++N +T
Sbjct: 490 YYSVAKALCEAGCNVNIKNREGET 513
Score = 62.9 bits (146), Expect = 5e-09
Identities = 38/123 (30%), Positives = 61/123 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D +G ALH AARYG + +L +N N ++K+ +TPLH AA + V + L
Sbjct: 438 LDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKAL 497
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ G N+N + TPL AS G + L + D+ + AL +A + +
Sbjct: 498 CEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQM 557
Query: 881 TII 883
+I
Sbjct: 558 EVI 560
Score = 60.5 bits (140), Expect = 3e-08
Identities = 36/126 (28%), Positives = 62/126 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D G A+++AAR+G + L N+ ++ ++K + LH+AA V +LL
Sbjct: 405 IDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLL 464
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
G+N N D TPLH A+ G AK L ++ + N +T L A + +
Sbjct: 465 CSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYH 524
Query: 881 TIIDLI 886
I++ +
Sbjct: 525 DIVECL 530
Score = 60.5 bits (140), Expect = 3e-08
Identities = 34/127 (26%), Positives = 58/127 (45%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N CD +G ALH A R E L+ V+ +++ TPLH+A + ++
Sbjct: 536 DLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA 595
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L + N++ + TPLH A+ G + + L + L KTA +A+ + H
Sbjct: 596 LCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQH 655
Query: 880 LTIIDLI 886
+ L+
Sbjct: 656 EHVAGLL 662
Score = 55.2 bits (127), Expect = 1e-06
Identities = 42/152 (27%), Positives = 66/152 (43%)
Query: 732 DKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
DKE+ L Y K +VN+ + G T L A+ G + L +
Sbjct: 475 DKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHG 534
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++N +K LHLA + VI+ LL G ++ D NTPLH A + GN+
Sbjct: 535 ADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV 594
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
L N ++ + N +T L +A + L ++
Sbjct: 595 ALCEANCNLDISNKYGRTPLHLAANNGILDVV 626
Score = 51.6 bits (118), Expect = 1e-05
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 6/141 (4%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ D T LH AA +G L NVN +N++ +TPL A+ ++ L
Sbjct: 472 NIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA-KDKVHL 880
++GA++NA D + LH A + K LLS + + T L VA KD
Sbjct: 532 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 591
Query: 881 TIIDLID-----NYANKYANT 896
++ L + + +NKY T
Sbjct: 592 IVVALCEANCNLDISNKYGRT 612
Score = 46.0 bits (104), Expect = 6e-04
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 1/145 (0%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D HG T LHVA G IV L E ++ ++ + LH A++ G +V+ L
Sbjct: 573 QDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLM 632
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK- 606
GA++ D T LA + H H + + + R + I + N + K
Sbjct: 633 GASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKDTHRGLFIQQLRPTQNLQPRIKLKL 692
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHK 631
+G+ G + + + L S+ +
Sbjct: 693 FGHSGSGKTTLVESLKCGLLRSFFR 717
Score = 44.8 bits (101), Expect = 0.001
Identities = 34/101 (33%), Positives = 47/101 (46%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
A DK+ +L + CQ KT V+ D +G T LH A + G L
Sbjct: 539 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
N++ NK +TPLHLAA N V+R L GA++ A+
Sbjct: 599 ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEAL 639
Score = 44.4 bits (100), Expect = 0.002
Identities = 28/120 (23%), Positives = 58/120 (48%)
Query: 755 SCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
S +++DVN + +G L AA G + +LI + ++ ++K ++ AA +
Sbjct: 366 SLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHV 425
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
++ L +N ++ D + LH A+ G+ A++L S+ + + + E+T L A
Sbjct: 426 DTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCA 485
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/152 (33%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
++ G T L AS G IVE L E G+++NA D + ALH A R V+ LL
Sbjct: 507 KNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQ 566
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G ++ ++ NTPLH+A +G++ V A+ N++ +N+ G TPLHLA+
Sbjct: 567 GCFVDYQDRHGNTPLHVACKDGNMPIVVAL------CEANCNLDISNKYGRTPLHLAANN 620
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
G + R L G+ + KTA D A +
Sbjct: 621 GILDVVRYLCLMGASVEALTTDGKTAEDLARS 652
Score = 73.7 bits (173), Expect = 3e-12
Identities = 47/160 (29%), Positives = 77/160 (48%), Gaps = 6/160 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D T LH A+ HG ++ + L E G +N + + L AS+RG+ +++ L
Sbjct: 474 QDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEH 533
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA++N + D + LHLAV + +K ++ + ++ + GNTPLH+A K
Sbjct: 534 GADLNACDKDGHIALHLAVRRCQMEVIKTLL------SQGCFVDYQDRHGNTPLHVACKD 587
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G I L E + N Y +T A N IL V++
Sbjct: 588 GNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVR 627
Score = 73.3 bits (172), Expect = 3e-12
Identities = 45/135 (33%), Positives = 69/135 (51%), Gaps = 6/135 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G A++ A+ HG ++ L E ++ D + ALH A+ GH +V +L
Sbjct: 408 QDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSF 467
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+N N ++ ++ TPLH A +G+ KA+ +G N+N N G TPL AS
Sbjct: 468 GSNPNIQDKEEETPLHCAAWHGYYSVAKALC----EAG--CNVNIKNREGETPLLTASAR 521
Query: 608 GYEGIARLLIEHGSE 622
GY I L EHG++
Sbjct: 522 GYHDIVECLAEHGAD 536
Score = 72.9 bits (171), Expect = 5e-12
Identities = 48/156 (30%), Positives = 75/156 (48%), Gaps = 7/156 (4%)
Query: 482 CPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVL 541
CP + +D G ALHVA+ +G A + + L GS N D E + LH A+ G+ +V
Sbjct: 436 CP-LDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVA 494
Query: 542 LMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
L +G N+N KN + TPL A G+ V+ + AEH ++N ++ G+ L
Sbjct: 495 KALCEAGCNVNIKNREGETPLLTASARGYHDIVECL---AEHGA---DLNACDKDGHIAL 548
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
HLA + + + L+ G Q+ + T A
Sbjct: 549 HLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA 584
Score = 65.3 bits (152), Expect = 9e-10
Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ HG L +A+ G I++ L++ GS I+ D +A+++A+ GH + L L +
Sbjct: 376 NKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENK 435
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ K+ LH+A GH + + F N N ++ TPLH A+ G
Sbjct: 436 CPLDVKDKSGEMALHVAARYGHADVAQLLCSFGS------NPNIQDKEEETPLHCAAWHG 489
Query: 609 YEGIARLLIEHGSEPSLQNSYHKT 632
Y +A+ L E G +++N +T
Sbjct: 490 YYSVAKALCEAGCNVNIKNREGET 513
Score = 62.9 bits (146), Expect = 5e-09
Identities = 38/123 (30%), Positives = 61/123 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D +G ALH AARYG + +L +N N ++K+ +TPLH AA + V + L
Sbjct: 438 LDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKAL 497
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ G N+N + TPL AS G + L + D+ + AL +A + +
Sbjct: 498 CEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQM 557
Query: 881 TII 883
+I
Sbjct: 558 EVI 560
Score = 60.5 bits (140), Expect = 3e-08
Identities = 36/126 (28%), Positives = 62/126 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D G A+++AAR+G + L N+ ++ ++K + LH+AA V +LL
Sbjct: 405 IDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLL 464
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
G+N N D TPLH A+ G AK L ++ + N +T L A + +
Sbjct: 465 CSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYH 524
Query: 881 TIIDLI 886
I++ +
Sbjct: 525 DIVECL 530
Score = 60.5 bits (140), Expect = 3e-08
Identities = 34/127 (26%), Positives = 58/127 (45%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N CD +G ALH A R E L+ V+ +++ TPLH+A + ++
Sbjct: 536 DLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA 595
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L + N++ + TPLH A+ G + + L + L KTA +A+ + H
Sbjct: 596 LCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQH 655
Query: 880 LTIIDLI 886
+ L+
Sbjct: 656 EHVAGLL 662
Score = 55.2 bits (127), Expect = 1e-06
Identities = 42/152 (27%), Positives = 66/152 (43%)
Query: 732 DKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
DKE+ L Y K +VN+ + G T L A+ G + L +
Sbjct: 475 DKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHG 534
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++N +K LHLA + VI+ LL G ++ D NTPLH A + GN+
Sbjct: 535 ADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV 594
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
L N ++ + N +T L +A + L ++
Sbjct: 595 ALCEANCNLDISNKYGRTPLHLAANNGILDVV 626
Score = 51.6 bits (118), Expect = 1e-05
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 6/141 (4%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ D T LH AA +G L NVN +N++ +TPL A+ ++ L
Sbjct: 472 NIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA-KDKVHL 880
++GA++NA D + LH A + K LLS + + T L VA KD
Sbjct: 532 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 591
Query: 881 TIIDLID-----NYANKYANT 896
++ L + + +NKY T
Sbjct: 592 IVVALCEANCNLDISNKYGRT 612
Score = 46.0 bits (104), Expect = 6e-04
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 1/145 (0%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D HG T LHVA G IV L E ++ ++ + LH A++ G +V+ L
Sbjct: 573 QDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLM 632
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK- 606
GA++ D T LA + H H + + + R + I + N + K
Sbjct: 633 GASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKDTHRGLFIQQLRPTQNLQPRIKLKL 692
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHK 631
+G+ G + + + L S+ +
Sbjct: 693 FGHSGSGKTTLVESLKCGLLRSFFR 717
Score = 44.8 bits (101), Expect = 0.001
Identities = 34/101 (33%), Positives = 47/101 (46%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
A DK+ +L + CQ KT V+ D +G T LH A + G L
Sbjct: 539 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
N++ NK +TPLHLAA N V+R L GA++ A+
Sbjct: 599 ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEAL 639
Score = 44.4 bits (100), Expect = 0.002
Identities = 28/120 (23%), Positives = 58/120 (48%)
Query: 755 SCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
S +++DVN + +G L AA G + +LI + ++ ++K ++ AA +
Sbjct: 366 SLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHV 425
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
++ L +N ++ D + LH A+ G+ A++L S+ + + + E+T L A
Sbjct: 426 DTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCA 485
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/152 (33%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
++ G T L AS G IVE L E G+++NA D + ALH A R V+ LL
Sbjct: 507 KNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQ 566
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G ++ ++ NTPLH+A +G++ V A+ N++ +N+ G TPLHLA+
Sbjct: 567 GCFVDYQDRHGNTPLHVACKDGNMPIVVAL------CEANCNLDISNKYGRTPLHLAANN 620
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
G + R L G+ + KTA D A +
Sbjct: 621 GILDVVRYLCLMGASVEALTTDGKTAEDLARS 652
Score = 73.7 bits (173), Expect = 3e-12
Identities = 47/160 (29%), Positives = 77/160 (48%), Gaps = 6/160 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D T LH A+ HG ++ + L E G +N + + L AS+RG+ +++ L
Sbjct: 474 QDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEH 533
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA++N + D + LHLAV + +K ++ + ++ + GNTPLH+A K
Sbjct: 534 GADLNACDKDGHIALHLAVRRCQMEVIKTLL------SQGCFVDYQDRHGNTPLHVACKD 587
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G I L E + N Y +T A N IL V++
Sbjct: 588 GNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVR 627
Score = 73.3 bits (172), Expect = 3e-12
Identities = 45/135 (33%), Positives = 69/135 (51%), Gaps = 6/135 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G A++ A+ HG ++ L E ++ D + ALH A+ GH +V +L
Sbjct: 408 QDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSF 467
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+N N ++ ++ TPLH A +G+ KA+ +G N+N N G TPL AS
Sbjct: 468 GSNPNIQDKEEETPLHCAAWHGYYSVAKALC----EAG--CNVNIKNREGETPLLTASAR 521
Query: 608 GYEGIARLLIEHGSE 622
GY I L EHG++
Sbjct: 522 GYHDIVECLAEHGAD 536
Score = 72.9 bits (171), Expect = 5e-12
Identities = 48/156 (30%), Positives = 75/156 (48%), Gaps = 7/156 (4%)
Query: 482 CPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVL 541
CP + +D G ALHVA+ +G A + + L GS N D E + LH A+ G+ +V
Sbjct: 436 CP-LDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVA 494
Query: 542 LMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
L +G N+N KN + TPL A G+ V+ + AEH ++N ++ G+ L
Sbjct: 495 KALCEAGCNVNIKNREGETPLLTASARGYHDIVECL---AEHGA---DLNACDKDGHIAL 548
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
HLA + + + L+ G Q+ + T A
Sbjct: 549 HLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA 584
Score = 65.3 bits (152), Expect = 9e-10
Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ HG L +A+ G I++ L++ GS I+ D +A+++A+ GH + L L +
Sbjct: 376 NKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENK 435
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ K+ LH+A GH + + F N N ++ TPLH A+ G
Sbjct: 436 CPLDVKDKSGEMALHVAARYGHADVAQLLCSFGS------NPNIQDKEEETPLHCAAWHG 489
Query: 609 YEGIARLLIEHGSEPSLQNSYHKT 632
Y +A+ L E G +++N +T
Sbjct: 490 YYSVAKALCEAGCNVNIKNREGET 513
Score = 62.9 bits (146), Expect = 5e-09
Identities = 38/123 (30%), Positives = 61/123 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D +G ALH AARYG + +L +N N ++K+ +TPLH AA + V + L
Sbjct: 438 LDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKAL 497
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ G N+N + TPL AS G + L + D+ + AL +A + +
Sbjct: 498 CEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQM 557
Query: 881 TII 883
+I
Sbjct: 558 EVI 560
Score = 60.5 bits (140), Expect = 3e-08
Identities = 36/126 (28%), Positives = 62/126 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D G A+++AAR+G + L N+ ++ ++K + LH+AA V +LL
Sbjct: 405 IDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLL 464
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
G+N N D TPLH A+ G AK L ++ + N +T L A + +
Sbjct: 465 CSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYH 524
Query: 881 TIIDLI 886
I++ +
Sbjct: 525 DIVECL 530
Score = 60.5 bits (140), Expect = 3e-08
Identities = 34/127 (26%), Positives = 58/127 (45%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N CD +G ALH A R E L+ V+ +++ TPLH+A + ++
Sbjct: 536 DLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA 595
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L + N++ + TPLH A+ G + + L + L KTA +A+ + H
Sbjct: 596 LCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQH 655
Query: 880 LTIIDLI 886
+ L+
Sbjct: 656 EHVAGLL 662
Score = 55.2 bits (127), Expect = 1e-06
Identities = 42/152 (27%), Positives = 66/152 (43%)
Query: 732 DKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
DKE+ L Y K +VN+ + G T L A+ G + L +
Sbjct: 475 DKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHG 534
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++N +K LHLA + VI+ LL G ++ D NTPLH A + GN+
Sbjct: 535 ADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV 594
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
L N ++ + N +T L +A + L ++
Sbjct: 595 ALCEANCNLDISNKYGRTPLHLAANNGILDVV 626
Score = 51.6 bits (118), Expect = 1e-05
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 6/141 (4%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ D T LH AA +G L NVN +N++ +TPL A+ ++ L
Sbjct: 472 NIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA-KDKVHL 880
++GA++NA D + LH A + K LLS + + T L VA KD
Sbjct: 532 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 591
Query: 881 TIIDLID-----NYANKYANT 896
++ L + + +NKY T
Sbjct: 592 IVVALCEANCNLDISNKYGRT 612
Score = 46.0 bits (104), Expect = 6e-04
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 1/145 (0%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D HG T LHVA G IV L E ++ ++ + LH A++ G +V+ L
Sbjct: 573 QDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLM 632
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK- 606
GA++ D T LA + H H + + + R + I + N + K
Sbjct: 633 GASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKDTHRGLFIQQLRPTQNLQPRIKLKL 692
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHK 631
+G+ G + + + L S+ +
Sbjct: 693 FGHSGSGKTTLVESLKCGLLRSFFR 717
Score = 44.8 bits (101), Expect = 0.001
Identities = 34/101 (33%), Positives = 47/101 (46%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
A DK+ +L + CQ KT V+ D +G T LH A + G L
Sbjct: 539 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
N++ NK +TPLHLAA N V+R L GA++ A+
Sbjct: 599 ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEAL 639
Score = 44.4 bits (100), Expect = 0.002
Identities = 28/120 (23%), Positives = 58/120 (48%)
Query: 755 SCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
S +++DVN + +G L AA G + +LI + ++ ++K ++ AA +
Sbjct: 366 SLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHV 425
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
++ L +N ++ D + LH A+ G+ A++L S+ + + + E+T L A
Sbjct: 426 DTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCA 485
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/152 (33%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
++ G T L AS G IVE L E G+++NA D + ALH A R V+ LL
Sbjct: 507 KNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQ 566
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G ++ ++ NTPLH+A +G++ V A+ N++ +N+ G TPLHLA+
Sbjct: 567 GCFVDYQDRHGNTPLHVACKDGNMPIVVAL------CEANCNLDISNKYGRTPLHLAANN 620
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
G + R L G+ + KTA D A +
Sbjct: 621 GILDVVRYLCLMGASVEALTTDGKTAEDLARS 652
Score = 73.7 bits (173), Expect = 3e-12
Identities = 47/160 (29%), Positives = 77/160 (48%), Gaps = 6/160 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D T LH A+ HG ++ + L E G +N + + L AS+RG+ +++ L
Sbjct: 474 QDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEH 533
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA++N + D + LHLAV + +K ++ + ++ + GNTPLH+A K
Sbjct: 534 GADLNACDKDGHIALHLAVRRCQMEVIKTLL------SQGCFVDYQDRHGNTPLHVACKD 587
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G I L E + N Y +T A N IL V++
Sbjct: 588 GNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVR 627
Score = 73.3 bits (172), Expect = 3e-12
Identities = 45/135 (33%), Positives = 69/135 (51%), Gaps = 6/135 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G A++ A+ HG ++ L E ++ D + ALH A+ GH +V +L
Sbjct: 408 QDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSF 467
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+N N ++ ++ TPLH A +G+ KA+ +G N+N N G TPL AS
Sbjct: 468 GSNPNIQDKEEETPLHCAAWHGYYSVAKALC----EAG--CNVNIKNREGETPLLTASAR 521
Query: 608 GYEGIARLLIEHGSE 622
GY I L EHG++
Sbjct: 522 GYHDIVECLAEHGAD 536
Score = 72.9 bits (171), Expect = 5e-12
Identities = 48/156 (30%), Positives = 75/156 (48%), Gaps = 7/156 (4%)
Query: 482 CPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVL 541
CP + +D G ALHVA+ +G A + + L GS N D E + LH A+ G+ +V
Sbjct: 436 CP-LDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVA 494
Query: 542 LMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
L +G N+N KN + TPL A G+ V+ + AEH ++N ++ G+ L
Sbjct: 495 KALCEAGCNVNIKNREGETPLLTASARGYHDIVECL---AEHGA---DLNACDKDGHIAL 548
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
HLA + + + L+ G Q+ + T A
Sbjct: 549 HLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA 584
Score = 65.3 bits (152), Expect = 9e-10
Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ HG L +A+ G I++ L++ GS I+ D +A+++A+ GH + L L +
Sbjct: 376 NKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENK 435
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ K+ LH+A GH + + F N N ++ TPLH A+ G
Sbjct: 436 CPLDVKDKSGEMALHVAARYGHADVAQLLCSFGS------NPNIQDKEEETPLHCAAWHG 489
Query: 609 YEGIARLLIEHGSEPSLQNSYHKT 632
Y +A+ L E G +++N +T
Sbjct: 490 YYSVAKALCEAGCNVNIKNREGET 513
Score = 62.9 bits (146), Expect = 5e-09
Identities = 38/123 (30%), Positives = 61/123 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D +G ALH AARYG + +L +N N ++K+ +TPLH AA + V + L
Sbjct: 438 LDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKAL 497
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ G N+N + TPL AS G + L + D+ + AL +A + +
Sbjct: 498 CEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQM 557
Query: 881 TII 883
+I
Sbjct: 558 EVI 560
Score = 60.5 bits (140), Expect = 3e-08
Identities = 36/126 (28%), Positives = 62/126 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D G A+++AAR+G + L N+ ++ ++K + LH+AA V +LL
Sbjct: 405 IDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLL 464
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
G+N N D TPLH A+ G AK L ++ + N +T L A + +
Sbjct: 465 CSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYH 524
Query: 881 TIIDLI 886
I++ +
Sbjct: 525 DIVECL 530
Score = 60.5 bits (140), Expect = 3e-08
Identities = 34/127 (26%), Positives = 58/127 (45%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N CD +G ALH A R E L+ V+ +++ TPLH+A + ++
Sbjct: 536 DLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA 595
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L + N++ + TPLH A+ G + + L + L KTA +A+ + H
Sbjct: 596 LCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQH 655
Query: 880 LTIIDLI 886
+ L+
Sbjct: 656 EHVAGLL 662
Score = 55.2 bits (127), Expect = 1e-06
Identities = 42/152 (27%), Positives = 66/152 (43%)
Query: 732 DKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
DKE+ L Y K +VN+ + G T L A+ G + L +
Sbjct: 475 DKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHG 534
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++N +K LHLA + VI+ LL G ++ D NTPLH A + GN+
Sbjct: 535 ADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV 594
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
L N ++ + N +T L +A + L ++
Sbjct: 595 ALCEANCNLDISNKYGRTPLHLAANNGILDVV 626
Score = 51.6 bits (118), Expect = 1e-05
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 6/141 (4%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ D T LH AA +G L NVN +N++ +TPL A+ ++ L
Sbjct: 472 NIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA-KDKVHL 880
++GA++NA D + LH A + K LLS + + T L VA KD
Sbjct: 532 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 591
Query: 881 TIIDLID-----NYANKYANT 896
++ L + + +NKY T
Sbjct: 592 IVVALCEANCNLDISNKYGRT 612
Score = 46.0 bits (104), Expect = 6e-04
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 1/145 (0%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D HG T LHVA G IV L E ++ ++ + LH A++ G +V+ L
Sbjct: 573 QDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLM 632
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK- 606
GA++ D T LA + H H + + + R + I + N + K
Sbjct: 633 GASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKDTHRGLFIQQLRPTQNLQPRIKLKL 692
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHK 631
+G+ G + + + L S+ +
Sbjct: 693 FGHSGSGKTTLVESLKCGLLRSFFR 717
Score = 44.8 bits (101), Expect = 0.001
Identities = 34/101 (33%), Positives = 47/101 (46%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
A DK+ +L + CQ KT V+ D +G T LH A + G L
Sbjct: 539 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
N++ NK +TPLHLAA N V+R L GA++ A+
Sbjct: 599 ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEAL 639
Score = 44.4 bits (100), Expect = 0.002
Identities = 28/120 (23%), Positives = 58/120 (48%)
Query: 755 SCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
S +++DVN + +G L AA G + +LI + ++ ++K ++ AA +
Sbjct: 366 SLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHV 425
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
++ L +N ++ D + LH A+ G+ A++L S+ + + + E+T L A
Sbjct: 426 DTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCA 485
>AL159174-2|CAI39610.1| 640|Homo sapiens ankyrin repeat domain 6
protein.
Length = 640
Score = 77.0 bits (181), Expect = 3e-13
Identities = 49/188 (26%), Positives = 97/188 (51%), Gaps = 8/188 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G TALH AS HG + + L++ G+ + A + +ALH A H +LL +
Sbjct: 17 QDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLA 76
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+ + KN +T LH+A HL ++ ++ +++ N++G+T LH+A+
Sbjct: 77 GSRADLKNNAGDTCLHVAARYNHLSIIRLLL------TAFCSVHEKNQAGDTALHVAAAL 130
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYA--HNLRILQVLKSCTPNLFEYIHITSSEVK 665
++ +A++L+E G++ ++ N+ +T + A HN + +L + P + + S K
Sbjct: 131 NHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKK 190
Query: 666 KISCESEK 673
+ + E+
Sbjct: 191 RERLKEER 198
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/141 (29%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Query: 507 IVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAV 566
I+ L+ G ++ D + +ALH AS G +L+ +GAN+ KN NT LHLA
Sbjct: 3 IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLAC 62
Query: 567 NNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQ 626
N H + ++ + K N +G+T LH+A+++ + I RLL+ +
Sbjct: 63 QNSHSQSTRVLLLAGSRADLK------NNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEK 116
Query: 627 NSYHKTAFDYAHNLRILQVLK 647
N TA A L +V K
Sbjct: 117 NQAGDTALHVAAALNHKKVAK 137
Score = 60.1 bits (139), Expect = 3e-08
Identities = 39/122 (31%), Positives = 62/122 (50%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D +G TALH A+ +G + +LI ANV +NK T LHLA N+ + R+LL G
Sbjct: 18 DKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAG 77
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
+ + + A +T LH A+ ++ ++LL+ + N TAL VA H +
Sbjct: 78 SRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAK 137
Query: 885 LI 886
++
Sbjct: 138 IL 139
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/108 (32%), Positives = 55/108 (50%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G TALH A + + +L+ + + +N T LH+AA N +IRLLL ++
Sbjct: 54 GNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 113
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
+ + A +T LH A+ + AKILL D T++N +T L A+
Sbjct: 114 HEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETAR 161
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G T LH AARY +L+ +V+ +N+ T LH+AA N V ++LL+ GA+
Sbjct: 87 GDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADT 146
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++ A TPL A N A +LL+ P +
Sbjct: 147 TIVNNAGQTPLETARYHNNPEVA-LLLTKAPQV 178
Score = 48.8 bits (111), Expect = 8e-05
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 6/130 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+++ G TALH+A + + LL GS + + + LH A+ H +++ +LL
Sbjct: 49 AKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLT 108
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+ ++++KN +T LH+A H K ++ +G I N +G TPL A
Sbjct: 109 AFCSVHEKNQAGDTALHVAAALNHKKVAKILL----EAGADTTI--VNNAGQTPLETARY 162
Query: 607 WGYEGIARLL 616
+A LL
Sbjct: 163 HNNPEVALLL 172
Score = 46.4 bits (105), Expect = 5e-04
Identities = 33/105 (31%), Positives = 51/105 (48%)
Query: 782 EFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDA 841
E LI ++ ++K T LH A+ + + +LL+ GAN+ A + A NT LH A
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 842 SETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+ + + ++LL L N T L VA HL+II L+
Sbjct: 62 CQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLL 106
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/66 (31%), Positives = 32/66 (48%)
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
T +I L+ G ++ D NT LH+AS G +AK+L+ ++ N TAL +
Sbjct: 1 TEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHL 60
Query: 874 AKDKVH 879
A H
Sbjct: 61 ACQNSH 66
>AL096678-3|CAI42281.1| 640|Homo sapiens ankyrin repeat domain 6
protein.
Length = 640
Score = 77.0 bits (181), Expect = 3e-13
Identities = 49/188 (26%), Positives = 97/188 (51%), Gaps = 8/188 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G TALH AS HG + + L++ G+ + A + +ALH A H +LL +
Sbjct: 17 QDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLA 76
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+ + KN +T LH+A HL ++ ++ +++ N++G+T LH+A+
Sbjct: 77 GSRADLKNNAGDTCLHVAARYNHLSIIRLLL------TAFCSVHEKNQAGDTALHVAAAL 130
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYA--HNLRILQVLKSCTPNLFEYIHITSSEVK 665
++ +A++L+E G++ ++ N+ +T + A HN + +L + P + + S K
Sbjct: 131 NHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKK 190
Query: 666 KISCESEK 673
+ + E+
Sbjct: 191 RERLKEER 198
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/141 (29%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Query: 507 IVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAV 566
I+ L+ G ++ D + +ALH AS G +L+ +GAN+ KN NT LHLA
Sbjct: 3 IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLAC 62
Query: 567 NNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQ 626
N H + ++ + K N +G+T LH+A+++ + I RLL+ +
Sbjct: 63 QNSHSQSTRVLLLAGSRADLK------NNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEK 116
Query: 627 NSYHKTAFDYAHNLRILQVLK 647
N TA A L +V K
Sbjct: 117 NQAGDTALHVAAALNHKKVAK 137
Score = 60.1 bits (139), Expect = 3e-08
Identities = 39/122 (31%), Positives = 62/122 (50%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D +G TALH A+ +G + +LI ANV +NK T LHLA N+ + R+LL G
Sbjct: 18 DKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAG 77
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
+ + + A +T LH A+ ++ ++LL+ + N TAL VA H +
Sbjct: 78 SRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAK 137
Query: 885 LI 886
++
Sbjct: 138 IL 139
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/108 (32%), Positives = 55/108 (50%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G TALH A + + +L+ + + +N T LH+AA N +IRLLL ++
Sbjct: 54 GNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 113
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
+ + A +T LH A+ + AKILL D T++N +T L A+
Sbjct: 114 HEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETAR 161
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G T LH AARY +L+ +V+ +N+ T LH+AA N V ++LL+ GA+
Sbjct: 87 GDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADT 146
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++ A TPL A N A +LL+ P +
Sbjct: 147 TIVNNAGQTPLETARYHNNPEVA-LLLTKAPQV 178
Score = 48.8 bits (111), Expect = 8e-05
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 6/130 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+++ G TALH+A + + LL GS + + + LH A+ H +++ +LL
Sbjct: 49 AKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLT 108
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+ ++++KN +T LH+A H K ++ +G I N +G TPL A
Sbjct: 109 AFCSVHEKNQAGDTALHVAAALNHKKVAKILL----EAGADTTI--VNNAGQTPLETARY 162
Query: 607 WGYEGIARLL 616
+A LL
Sbjct: 163 HNNPEVALLL 172
Score = 46.4 bits (105), Expect = 5e-04
Identities = 33/105 (31%), Positives = 51/105 (48%)
Query: 782 EFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDA 841
E LI ++ ++K T LH A+ + + +LL+ GAN+ A + A NT LH A
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 842 SETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
+ + + ++LL L N T L VA HL+II L+
Sbjct: 62 CQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLL 106
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/66 (31%), Positives = 32/66 (48%)
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
T +I L+ G ++ D NT LH+AS G +AK+L+ ++ N TAL +
Sbjct: 1 TEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHL 60
Query: 874 AKDKVH 879
A H
Sbjct: 61 ACQNSH 66
>AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ45958 fis, clone PLACE7011559, highly similar
to Death-associated protein kinase 1 (EC 2.7.1.-). ).
Length = 337
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/152 (33%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
++ G T L AS G IVE L E G+++NA D + ALH A R V+ LL
Sbjct: 61 KNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQ 120
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G ++ ++ NTPLH+A +G++ V A+ N++ +N+ G TPLHLA+
Sbjct: 121 GCFVDYQDRHGNTPLHVACKDGNMPIVVAL------CEANCNLDISNKYGRTPLHLAANN 174
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
G + R L G+ + KTA D A +
Sbjct: 175 GILDVVRYLCLMGASVEALTTDGKTAEDLARS 206
Score = 74.1 bits (174), Expect = 2e-12
Identities = 47/160 (29%), Positives = 77/160 (48%), Gaps = 6/160 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D T LH A+ HG ++ + L E G +N + + L AS+RG+ +++ L
Sbjct: 28 QDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEH 87
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA++N + D + LHLAV + +K ++ + ++ + GNTPLH+A K
Sbjct: 88 GADLNACDKDGHIALHLAVRRCQMEVIKTLL------SQGCFVDYQDRHGNTPLHVACKD 141
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G I L E + N Y +T A N IL V++
Sbjct: 142 GNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVR 181
Score = 70.1 bits (164), Expect = 3e-11
Identities = 45/143 (31%), Positives = 69/143 (48%), Gaps = 6/143 (4%)
Query: 495 ALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
ALHVA+ +G A + + L GS N D E + LH A+ GH +V L +G N+N K
Sbjct: 2 ALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIK 61
Query: 555 NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIAR 614
N + TPL A G+ V+ + AEH ++N ++ G+ LHLA + + +
Sbjct: 62 NREGETPLLTASARGYHDIVECL---AEHGA---DLNACDKDGHIALHLAVRRCQMEVIK 115
Query: 615 LLIEHGSEPSLQNSYHKTAFDYA 637
L+ G Q+ + T A
Sbjct: 116 TLLSQGCFVDYQDRHGNTPLHVA 138
Score = 60.5 bits (140), Expect = 3e-08
Identities = 34/127 (26%), Positives = 58/127 (45%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N CD +G ALH A R E L+ V+ +++ TPLH+A + ++
Sbjct: 90 DLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA 149
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L + N++ + TPLH A+ G + + L + L KTA +A+ + H
Sbjct: 150 LCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQH 209
Query: 880 LTIIDLI 886
+ L+
Sbjct: 210 EHVAGLL 216
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/113 (30%), Positives = 55/113 (48%)
Query: 771 ALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
ALH AARYG + +L +N N ++K+ +TPLH AA + V + L + G N+N
Sbjct: 2 ALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIK 61
Query: 831 DVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
+ TPL AS G + L + D+ + AL +A + + +I
Sbjct: 62 NREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVI 114
Score = 55.6 bits (128), Expect = 7e-07
Identities = 42/152 (27%), Positives = 66/152 (43%)
Query: 732 DKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
DKE+ L Y K +VN+ + G T L A+ G + L +
Sbjct: 29 DKEEETPLHCAAWHGHYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHG 88
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++N +K LHLA + VI+ LL G ++ D NTPLH A + GN+
Sbjct: 89 ADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV 148
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
L N ++ + N +T L +A + L ++
Sbjct: 149 ALCEANCNLDISNKYGRTPLHLAANNGILDVV 180
Score = 50.8 bits (116), Expect = 2e-05
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 6/141 (4%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ D T LH AA +G L NVN +N++ +TPL A+ ++ L
Sbjct: 26 NIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 85
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA-KDKVHL 880
++GA++NA D + LH A + K LLS + + T L VA KD
Sbjct: 86 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 145
Query: 881 TIIDLID-----NYANKYANT 896
++ L + + +NKY T
Sbjct: 146 IVVALCEANCNLDISNKYGRT 166
Score = 46.0 bits (104), Expect = 6e-04
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 1/145 (0%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D HG T LHVA G IV L E ++ ++ + LH A++ G +V+ L
Sbjct: 127 QDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLM 186
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK- 606
GA++ D T LA + H H + + + R + I + N + K
Sbjct: 187 GASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKDTHRGLFIQQLRPTQNLQPRIKLKL 246
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHK 631
+G+ G + + + L S+ +
Sbjct: 247 FGHSGSGKTTLVESLKCGLLRSFFR 271
Score = 44.8 bits (101), Expect = 0.001
Identities = 34/101 (33%), Positives = 47/101 (46%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
A DK+ +L + CQ KT V+ D +G T LH A + G L
Sbjct: 93 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 152
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
N++ NK +TPLHLAA N V+R L GA++ A+
Sbjct: 153 ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEAL 193
Score = 40.7 bits (91), Expect = 0.022
Identities = 25/82 (30%), Positives = 39/82 (47%)
Query: 805 LHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLN 864
LH+AA V +LL G+N N D TPLH A+ G+ AK L ++ + N
Sbjct: 3 LHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIKN 62
Query: 865 ATEKTALAVAKDKVHLTIIDLI 886
+T L A + + I++ +
Sbjct: 63 REGETPLLTASARGYHDIVECL 84
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/152 (33%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
++ G T L AS G IVE L E G+++NA D + ALH A R V+ LL
Sbjct: 510 KNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQ 569
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G ++ ++ NTPLH+A +G++ V A+ N++ +N+ G TPLHLA+
Sbjct: 570 GCFVDYQDRHGNTPLHVACKDGNMPIVVAL------CEANCNLDISNKYGRTPLHLAANN 623
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHN 639
G + R L G+ + KTA D A +
Sbjct: 624 GILDVVRYLCLMGASVEALTTDGKTAEDLARS 655
Score = 73.7 bits (173), Expect = 3e-12
Identities = 47/160 (29%), Positives = 77/160 (48%), Gaps = 6/160 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D T LH A+ HG ++ + L E G +N + + L AS+RG+ +++ L
Sbjct: 477 QDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEH 536
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA++N + D + LHLAV + +K ++ + ++ + GNTPLH+A K
Sbjct: 537 GADLNACDKDGHIALHLAVRRCQMEVIKTLL------SQGCFVDYQDRHGNTPLHVACKD 590
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
G I L E + N Y +T A N IL V++
Sbjct: 591 GNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVR 630
Score = 73.3 bits (172), Expect = 3e-12
Identities = 45/135 (33%), Positives = 69/135 (51%), Gaps = 6/135 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G A++ A+ HG ++ L E ++ D + ALH A+ GH +V +L
Sbjct: 411 QDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSF 470
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+N N ++ ++ TPLH A +G+ KA+ +G N+N N G TPL AS
Sbjct: 471 GSNPNIQDKEEETPLHCAAWHGYYSVAKALC----EAG--CNVNIKNREGETPLLTASAR 524
Query: 608 GYEGIARLLIEHGSE 622
GY I L EHG++
Sbjct: 525 GYHDIVECLAEHGAD 539
Score = 72.9 bits (171), Expect = 5e-12
Identities = 48/156 (30%), Positives = 75/156 (48%), Gaps = 7/156 (4%)
Query: 482 CPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVL 541
CP + +D G ALHVA+ +G A + + L GS N D E + LH A+ G+ +V
Sbjct: 439 CP-LDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVA 497
Query: 542 LMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
L +G N+N KN + TPL A G+ V+ + AEH ++N ++ G+ L
Sbjct: 498 KALCEAGCNVNIKNREGETPLLTASARGYHDIVECL---AEHGA---DLNACDKDGHIAL 551
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
HLA + + + L+ G Q+ + T A
Sbjct: 552 HLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA 587
Score = 65.3 bits (152), Expect = 9e-10
Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ HG L +A+ G I++ L++ GS I+ D +A+++A+ GH + L L +
Sbjct: 379 NKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENK 438
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
++ K+ LH+A GH + + F N N ++ TPLH A+ G
Sbjct: 439 CPLDVKDKSGEMALHVAARYGHADVAQLLCSFGS------NPNIQDKEEETPLHCAAWHG 492
Query: 609 YEGIARLLIEHGSEPSLQNSYHKT 632
Y +A+ L E G +++N +T
Sbjct: 493 YYSVAKALCEAGCNVNIKNREGET 516
Score = 62.9 bits (146), Expect = 5e-09
Identities = 38/123 (30%), Positives = 61/123 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D +G ALH AARYG + +L +N N ++K+ +TPLH AA + V + L
Sbjct: 441 LDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKAL 500
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
+ G N+N + TPL AS G + L + D+ + AL +A + +
Sbjct: 501 CEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQM 560
Query: 881 TII 883
+I
Sbjct: 561 EVI 563
Score = 60.5 bits (140), Expect = 3e-08
Identities = 36/126 (28%), Positives = 62/126 (49%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
++V D G A+++AAR+G + L N+ ++ ++K + LH+AA V +LL
Sbjct: 408 IDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLL 467
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
G+N N D TPLH A+ G AK L ++ + N +T L A + +
Sbjct: 468 CSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYH 527
Query: 881 TIIDLI 886
I++ +
Sbjct: 528 DIVECL 533
Score = 60.5 bits (140), Expect = 3e-08
Identities = 34/127 (26%), Positives = 58/127 (45%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N CD +G ALH A R E L+ V+ +++ TPLH+A + ++
Sbjct: 539 DLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA 598
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L + N++ + TPLH A+ G + + L + L KTA +A+ + H
Sbjct: 599 LCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQH 658
Query: 880 LTIIDLI 886
+ L+
Sbjct: 659 EHVAGLL 665
Score = 55.2 bits (127), Expect = 1e-06
Identities = 42/152 (27%), Positives = 66/152 (43%)
Query: 732 DKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNR 791
DKE+ L Y K +VN+ + G T L A+ G + L +
Sbjct: 478 DKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHG 537
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
A++N +K LHLA + VI+ LL G ++ D NTPLH A + GN+
Sbjct: 538 ADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV 597
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTII 883
L N ++ + N +T L +A + L ++
Sbjct: 598 ALCEANCNLDISNKYGRTPLHLAANNGILDVV 629
Score = 51.6 bits (118), Expect = 1e-05
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 6/141 (4%)
Query: 762 NVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLL 821
N+ D T LH AA +G L NVN +N++ +TPL A+ ++ L
Sbjct: 475 NIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 534
Query: 822 DNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA-KDKVHL 880
++GA++NA D + LH A + K LLS + + T L VA KD
Sbjct: 535 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 594
Query: 881 TIIDLID-----NYANKYANT 896
++ L + + +NKY T
Sbjct: 595 IVVALCEANCNLDISNKYGRT 615
Score = 46.0 bits (104), Expect = 6e-04
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 1/145 (0%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D HG T LHVA G IV L E ++ ++ + LH A++ G +V+ L
Sbjct: 576 QDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLM 635
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK- 606
GA++ D T LA + H H + + + R + I + N + K
Sbjct: 636 GASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKDTHRGLFIQQLRPTQNLQPRIKLKL 695
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHK 631
+G+ G + + + L S+ +
Sbjct: 696 FGHSGSGKTTLVESLKCGLLRSFFR 720
Score = 44.8 bits (101), Expect = 0.001
Identities = 34/101 (33%), Positives = 47/101 (46%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
A DK+ +L + CQ KT V+ D +G T LH A + G L
Sbjct: 542 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 601
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAI 830
N++ NK +TPLHLAA N V+R L GA++ A+
Sbjct: 602 ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEAL 642
Score = 44.4 bits (100), Expect = 0.002
Identities = 28/120 (23%), Positives = 58/120 (48%)
Query: 755 SCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
S +++DVN + +G L AA G + +LI + ++ ++K ++ AA +
Sbjct: 369 SLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHV 428
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
++ L +N ++ D + LH A+ G+ A++L S+ + + + E+T L A
Sbjct: 429 DTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCA 488
>EF041819-1|ABL09300.1| 782|Homo sapiens several ankyrin repeat
protein transcript variant 2 protein.
Length = 782
Score = 76.6 bits (180), Expect = 4e-13
Identities = 40/132 (30%), Positives = 69/132 (52%), Gaps = 3/132 (2%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T++D G T LH+A+ HG + ++ +L G + TD E +HYA+ G L +L
Sbjct: 384 LTAQDDRGCTPLHLAATHGHSFTLQIMLRSGDP-SVTDKREWRPVHYAAFHGRLGCLQLL 442
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ G +I + + N P+HLA GHLHC K ++ + S + N++G L LA
Sbjct: 443 VKWGCSIEDVDYNGNLPVHLAAMEGHLHCFKFLV--SRMSSATQVLKAFNDNGENVLDLA 500
Query: 605 SKWGYEGIARLL 616
++ + I + +
Sbjct: 501 QRFFKQNILQFI 512
Score = 66.1 bits (154), Expect = 5e-10
Identities = 40/138 (28%), Positives = 72/138 (52%), Gaps = 9/138 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T + G TA H+A+I G+ V+ L+ G+ + A D C+ LH A++ GH L ++
Sbjct: 351 ITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIM 410
Query: 545 LHSG-ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L SG ++ K + P+H A +G L C++ ++ + +I + +GN P+HL
Sbjct: 411 LRSGDPSVTDKR--EWRPVHYAAFHGRLGCLQLLVKWG------CSIEDVDYNGNLPVHL 462
Query: 604 ASKWGYEGIARLLIEHGS 621
A+ G+ + L+ S
Sbjct: 463 AAMEGHLHCFKFLVSRMS 480
Score = 57.6 bits (133), Expect = 2e-07
Identities = 88/344 (25%), Positives = 140/344 (40%), Gaps = 38/344 (11%)
Query: 496 LHVASIHG--KATIVETLLEM---GSEINATD-LNECSALHYASSRGHQNVLLMLLHSGA 549
+H SIH +A V+ L E+ G+ IN D L++ + LH+A+ G L LL GA
Sbjct: 290 VHFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGA 349
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+I T H+A G CV+A+I N+ ++ G TPLHLA+ G+
Sbjct: 350 DITHVTTRGWTASHIAAIRGQDACVQALIM------NGANLTAQDDRGCTPLHLAATHGH 403
Query: 610 EGIARLLIEHGSEPSLQNSYHKTAFDYA--H-NLRILQVLK--SCTPNLFEY-----IHI 659
++++ G +PS+ + YA H L LQ+L C+ +Y +H+
Sbjct: 404 SFTLQIMLRSG-DPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHL 462
Query: 660 TSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACF 719
+ E + C + + LK ND + + L L +R + + F
Sbjct: 463 AAME-GHLHCFKFLVSRMSSATQVLKA--FNDNGENV--LDLAQRFFKQ------NILQF 511
Query: 720 YMNIDYSAFIAPDKEKSNSLCHPLC---ECQYCKRKTESCTDFDVNVCDSNGFTALHYAA 776
+Y D+E H + K+ E ++N NG T +H AA
Sbjct: 512 IQGAEYEGKDLEDQETLAFPGHVAAFKGDLGMLKKLVEDGV-ININERADNGSTPMHKAA 570
Query: 777 RYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
G E LI A+ N NK + P +A ++LL
Sbjct: 571 GQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVKLL 614
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/121 (28%), Positives = 62/121 (51%), Gaps = 1/121 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ + G+TA H AA G D LI N AN+ ++ + TPLHLAA + + +++
Sbjct: 350 DITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQI 409
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
+L +G + + D P+H A+ G +G ++L+ + I ++ + +A + H
Sbjct: 410 MLRSG-DPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGH 468
Query: 880 L 880
L
Sbjct: 469 L 469
Score = 55.6 bits (128), Expect = 7e-07
Identities = 33/94 (35%), Positives = 53/94 (56%), Gaps = 1/94 (1%)
Query: 769 FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
FT LH+AA G E + L+++ A++ + T H+AAI + ++ L+ NGAN+
Sbjct: 326 FTPLHWAAHSGSLECLHWLLWHGADITHVTTRGWTASHIAAIRGQDACVQALIMNGANLT 385
Query: 829 AIDVARNTPLHDASETGNIGAAKILL-SYNPDIT 861
A D TPLH A+ G+ +I+L S +P +T
Sbjct: 386 AQDDRGCTPLHLAATHGHSFTLQIMLRSGDPSVT 419
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 7/130 (5%)
Query: 491 HGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGAN 550
H T LH A+ G + LL G++I +A H A+ RG + L+ +GAN
Sbjct: 324 HKFTPLHWAAHSGSLECLHWLLWHGADITHVTTRGWTASHIAAIRGQDACVQALIMNGAN 383
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
+ ++ TPLHLA +GH ++ ++ R + + ++ P+H A+ G
Sbjct: 384 LTAQDDRGCTPLHLAATHGHSFTLQIML-------RSGDPSVTDKREWRPVHYAAFHGRL 436
Query: 611 GIARLLIEHG 620
G +LL++ G
Sbjct: 437 GCLQLLVKWG 446
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 1/91 (1%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T LH AA +G F ++ + + +K+ P+H AA + + ++LL+ G
Sbjct: 388 DDRGCTPLHLAATHG-HSFTLQIMLRSGDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWG 446
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLS 855
+I +D N P+H A+ G++ K L+S
Sbjct: 447 CSIEDVDYNGNLPVHLAAMEGHLHCFKFLVS 477
Score = 41.5 bits (93), Expect = 0.013
Identities = 43/167 (25%), Positives = 76/167 (45%), Gaps = 15/167 (8%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSE----INATDLNECSALHYASSRGHQNVLLML 544
D +G +H+A++ G + L+ S + A + N + L A QN+L +
Sbjct: 453 DYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFI 512
Query: 545 LHSGANINQKNI-DKNT---PLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
GA K++ D+ T P H+A G L +K ++ ININ ++G+TP
Sbjct: 513 --QGAEYEGKDLEDQETLAFPGHVAAFKGDLGMLKKLV-----EDGVININERADNGSTP 565
Query: 601 LHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+H A+ G+ + LI+ G++ ++ N + D A L +K
Sbjct: 566 MHKAAGQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVK 612
Score = 40.3 bits (90), Expect = 0.030
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 804 PLHLAAINNKTVVIRLLLDNGA-NINAIDVARNTPLHDASETGNIGAAKILLSYNPDITL 862
P H+AA +++ L+++G NIN +TP+H A+ G+I + L+ D +
Sbjct: 531 PGHVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNI 590
Query: 863 LNATEKTALAVAKDKVHLTIIDLID 887
N + VAK HL + L++
Sbjct: 591 TNKAGERPSDVAKRFAHLAAVKLLE 615
Score = 39.9 bits (89), Expect = 0.039
Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 6/116 (5%)
Query: 497 HVASIHGKATIVETLLEMGS-EINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKN 555
HVA+ G +++ L+E G IN N + +H A+ +GH L L+ GA+ N N
Sbjct: 533 HVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITN 592
Query: 556 IDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
P +A HL VK + +K +I+ NE + + G EG
Sbjct: 593 KAGERPSDVAKRFAHLAAVKLL-----EELQKYDIDDENEIDENDVKYFIRHGVEG 643
Score = 34.3 bits (75), Expect = 1.9
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Query: 796 CRNKKAQT-PLHLAAINNKTVVIRLLLDNGANINAIDVARN-TPLHDASETGNIGAAKIL 853
C KK +H A + ++ GA+IN +DV TPLH A+ +G++ L
Sbjct: 285 CSRKKVHFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWL 344
Query: 854 LSYNPDITLLNATEKTALAVA 874
L + DIT + TA +A
Sbjct: 345 LWHGADITHVTTRGWTASHIA 365
Score = 32.3 bits (70), Expect = 7.9
Identities = 18/61 (29%), Positives = 28/61 (45%)
Query: 793 NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKI 852
N+N R TP+H AA ++ L+ GA+ N + A P A ++ A K+
Sbjct: 554 NINERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVKL 613
Query: 853 L 853
L
Sbjct: 614 L 614
>BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 76.6 bits (180), Expect = 4e-13
Identities = 98/397 (24%), Positives = 168/397 (42%), Gaps = 22/397 (5%)
Query: 495 ALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQK 554
+L A G V LL+ +N S L A S G+ + +LL AN+ +
Sbjct: 208 SLAEACSDGDVNAVRKLLDECRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDR 267
Query: 555 -NIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N TPL A + G+L VK ++ H ++N + +GNT L A G+ I
Sbjct: 268 GNKGDITPLMAASSGGYLDIVKLLLL---HDA---DVNSQSATGNTALTYACAGGFVDIV 321
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESE- 672
++L+ G+ N T A + ++V + + I+ S+E K+ +
Sbjct: 322 KVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDH-GAGINTHSNEFKESALTLAC 380
Query: 673 KPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPD 732
L + L+ + KT E + ++ A G V++A ++ + D
Sbjct: 381 YKGHLDMVRFLLEAG-ADQEHKTDE---MHTALMEACMDGHVEVARLLLDSGAQVNMPAD 436
Query: 733 KEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSN--GFTALHYAARYGLDEFCNILIFN 790
+S L C + N+ + N G+T L AAR G +E +L+
Sbjct: 437 SFESPLT---LAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQ 493
Query: 791 RANVNCRNKKAQ-TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
AN+N + ++ Q T L LA + V L+ GA+I ++ +TPL +AS+ G++
Sbjct: 494 GANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLMEASQEGHLEL 550
Query: 850 AKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
K LL+ ++ AT TAL A + H + D++
Sbjct: 551 VKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Score = 62.5 bits (145), Expect = 6e-09
Identities = 44/141 (31%), Positives = 74/141 (52%), Gaps = 5/141 (3%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L AS G IV+ LL +++N+ +AL YA + G +++ +LL+ GANI
Sbjct: 273 ITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIE 332
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +H G IN + +NE + L LA G+ +
Sbjct: 333 DHNENGHTPLMEAASAGHVEVARVLL---DH-GAGINTH-SNEFKESALTLACYKGHLDM 387
Query: 613 ARLLIEHGSEPSLQNSYHKTA 633
R L+E G++ + TA
Sbjct: 388 VRFLLEAGADQEHKTDEMHTA 408
Score = 58.0 bits (134), Expect = 1e-07
Identities = 92/379 (24%), Positives = 154/379 (40%), Gaps = 31/379 (8%)
Query: 528 ALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRK 587
+L A S G N + LL ++N+ + + L LA + G+ + ++ A H+ +
Sbjct: 208 SLAEACSDGDVNAVRKLLDECRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVE 265
Query: 588 ININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ N+ TPL AS GY I +LL+ H ++ + Q++ TA YA
Sbjct: 266 ---DRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYA---------- 312
Query: 648 SCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILR 707
C + + + +E I +E + ++ A +++ I
Sbjct: 313 -CAGGFVDIVKVLLNEGANIEDHNENGHTPLME--AASAGHVEVARVLLDHGAGINTHSN 369
Query: 708 AISYGDVKLACFYMNIDYSAFI----APDKEKSNSLCHPLCE-CQYCKRKTESC---TDF 759
+ LAC+ ++D F+ A + K++ + L E C + +
Sbjct: 370 EFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGA 429
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
VN+ + + L AA G E +LI AN+ N + TPL AA ++ L
Sbjct: 430 QVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVAL 489
Query: 820 LLDNGANINA-IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GANINA + + T L A G A L+ DI L T L A +
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL---GCSTPLMEASQEG 546
Query: 879 HLTIID-LIDNYANKYANT 896
HL ++ L+ + AN +A T
Sbjct: 547 HLELVKYLLASGANVHATT 565
Score = 58.0 bits (134), Expect = 1e-07
Identities = 44/135 (32%), Positives = 72/135 (53%), Gaps = 9/135 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNEC--SALHYASSRGHQNVLLMLLH 546
+ +G T L A+ G + LL+ G+ IN T NE SAL A +GH +++ LL
Sbjct: 335 NENGHTPLMEAASAGHVEVARVLLDHGAGIN-THSNEFKESALTLACYKGHLDMVRFLLE 393
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+GA+ K + +T L A +GH+ + ++ SG ++N+ +S +PL LA+
Sbjct: 394 AGADQEHKTDEMHTALMEACMDGHVEVARLLL----DSGAQVNMPA--DSFESPLTLAAC 447
Query: 607 WGYEGIARLLIEHGS 621
G+ +A LLIE G+
Sbjct: 448 GGHVELAALLIERGA 462
Score = 57.6 bits (133), Expect = 2e-07
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
+AL +A G +V LLE G++ +AL A GH V +LL SGA +N
Sbjct: 374 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 433
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
+PL LA GH+ +I R N+ N+ G TPL A++ G+E +
Sbjct: 434 PADSFESPLTLAACGGHVELAALLIE------RGANLEEVNDEGYTPLMEAAREGHEEMV 487
Query: 614 RLLIEHGSEPSLQ 626
LL+ G+ + Q
Sbjct: 488 ALLLAQGANINAQ 500
Score = 56.4 bits (130), Expect = 4e-07
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TAL A + G + LL+ G+++N + S L A+ GH + +L+ GAN+ +
Sbjct: 407 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEE 466
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N + TPL A GH V ++ G IN E+ T L LA G+ +A
Sbjct: 467 VNDEGYTPLMEAAREGHEEMVALLL----AQGANINAQ-TEETQETALTLACCGGFSEVA 521
Query: 614 RLLIEHGSEPSL 625
LI+ G++ L
Sbjct: 522 DFLIKAGADIEL 533
Score = 52.0 bits (119), Expect = 9e-06
Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINA-TDLNECSALHYASSRGHQNVLLMLLHS 547
+ G T L A+ G +V LL G+ INA T+ + +AL A G V L+ +
Sbjct: 468 NDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA+I + +TPL A GHL VK ++ SG N++ +G+T L A +
Sbjct: 528 GADIE---LGCSTPLMEASQEGHLELVKYLL----ASG--ANVHATTATGDTALTYACEN 578
Query: 608 GYEGIARLLIEHGSE 622
G+ +A +L++ G++
Sbjct: 579 GHTDVADVLLQAGAD 593
Score = 41.1 bits (92), Expect = 0.017
Identities = 22/61 (36%), Positives = 36/61 (59%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L AS G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++++
Sbjct: 537 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDK 596
Query: 554 K 554
+
Sbjct: 597 Q 597
Score = 39.1 bits (87), Expect = 0.068
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TAL A G E + LI A++ TPL A+ +++ LL +GAN++A
Sbjct: 507 TALTLACCGGFSEVADFLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHA 563
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDI 860
+T L A E G+ A +LL D+
Sbjct: 564 TTATGDTALTYACENGHTDVADVLLQAGADL 594
>AY057056-1|AAL25260.1| 151|Homo sapiens hepatocellular
carcinoma-associated protein p28-II protein.
Length = 151
Score = 76.6 bits (180), Expect = 4e-13
Identities = 44/129 (34%), Positives = 68/129 (52%), Gaps = 6/129 (4%)
Query: 509 ETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNN 568
E++L S TD + +ALH+A S GH ++ LL G +N K+ +PLH+A +
Sbjct: 24 ESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASA 83
Query: 569 GHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNS 628
G VKA++ G+ +N N++G TPLH A+ IA +L+E G+ P ++
Sbjct: 84 GRDEIVKALL------GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH 137
Query: 629 YHKTAFDYA 637
Y TA A
Sbjct: 138 YEATAMHRA 146
Score = 66.1 bits (154), Expect = 5e-10
Identities = 30/81 (37%), Positives = 50/81 (61%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +D G + LH+A+ G+ IV+ LL G+++NA + N C+ LHYA+S+ + +ML
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 545 LHSGANINQKNIDKNTPLHLA 565
L GAN + K+ + T +H A
Sbjct: 126 LEGGANPDAKDHYEATAMHRA 146
Score = 58.4 bits (135), Expect = 1e-07
Identities = 37/88 (42%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T T +DS TALH A G IVE LL++G +N D S LH A+S G ++
Sbjct: 34 TRTDQDSR--TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKA 91
Query: 544 LLHSGANINQKNIDKNTPLHLAVN-NGH 570
LL GA +N N + TPLH A + N H
Sbjct: 92 LLGKGAQVNAVNQNGCTPLHYAASKNRH 119
Score = 58.4 bits (135), Expect = 1e-07
Identities = 33/82 (40%), Positives = 44/82 (53%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G++ LH AA G DE L+ A VN N+ TPLH AA N+ + +L
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 821 LDNGANINAIDVARNTPLHDAS 842
L+ GAN +A D T +H A+
Sbjct: 126 LEGGANPDAKDHYEATAMHRAA 147
Score = 56.8 bits (131), Expect = 3e-07
Identities = 37/114 (32%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D + TALH+A G E L+ VN ++ +PLH+AA + +++ LL G
Sbjct: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL--AVAKD 876
A +NA++ TPLH A+ A +LL + + E TA+ A AKD
Sbjct: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKD 150
Score = 42.3 bits (95), Expect = 0.007
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Query: 780 LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLH 839
L+E ++ +++ ++ ++T LH A T ++ LL G +N D A +PLH
Sbjct: 19 LEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLH 78
Query: 840 DASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK-VHLTIIDLIDNYAN 891
A+ G K LL + +N T L A K H + L++ AN
Sbjct: 79 IAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN 131
>AL117504-1|CAB55968.1| 641|Homo sapiens hypothetical protein
protein.
Length = 641
Score = 76.6 bits (180), Expect = 4e-13
Identities = 49/188 (26%), Positives = 97/188 (51%), Gaps = 8/188 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G TALH AS HG + + L++ G+ + A + +ALH A H +LL +
Sbjct: 18 QDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLA 77
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+ + KN +T LH+A HL ++ ++ +++ N++G+T LH+A+
Sbjct: 78 GSRADLKNNAGDTCLHVAARYNHLSIIRLLL------TAFCSVHEKNQAGDTALHVAAAL 131
Query: 608 GYEGIARLLIEHGSEPSLQNSYHKTAFDYA--HNLRILQVLKSCTPNLFEYIHITSSEVK 665
++ +A++L+E G++ ++ N+ +T + A HN + +L + P + + S K
Sbjct: 132 NHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKK 191
Query: 666 KISCESEK 673
+ + E+
Sbjct: 192 RERLKEER 199
Score = 62.5 bits (145), Expect = 6e-09
Identities = 42/141 (29%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Query: 507 IVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAV 566
I+ L+ G ++ D + +ALH AS G +L+ +GAN+ KN NT LHLA
Sbjct: 4 IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLAC 63
Query: 567 NNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQ 626
N H + ++ + K N +G+T LH+A+++ + I RLL+ +
Sbjct: 64 QNSHSQSTRVLLLAGSRADLK------NNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEK 117
Query: 627 NSYHKTAFDYAHNLRILQVLK 647
N TA A L +V K
Sbjct: 118 NQAGDTALHVAAALNHKKVAK 138
Score = 59.7 bits (138), Expect = 5e-08
Identities = 38/122 (31%), Positives = 62/122 (50%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D +G TALH A+ +G + +L+ ANV +NK T LHLA N+ + R+LL G
Sbjct: 19 DKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAG 78
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
+ + + A +T LH A+ ++ ++LL+ + N TAL VA H +
Sbjct: 79 SRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAK 138
Query: 885 LI 886
++
Sbjct: 139 IL 140
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/108 (32%), Positives = 55/108 (50%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G TALH A + + +L+ + + +N T LH+AA N +IRLLL ++
Sbjct: 55 GNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 114
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
+ + A +T LH A+ + AKILL D T++N +T L A+
Sbjct: 115 HEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETAR 162
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G T LH AARY +L+ +V+ +N+ T LH+AA N V ++LL+ GA+
Sbjct: 88 GDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADT 147
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++ A TPL A N A +LL+ P +
Sbjct: 148 TIVNNAGQTPLETARYHNNPEVA-LLLTKAPQV 179
Score = 48.8 bits (111), Expect = 8e-05
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 6/130 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+++ G TALH+A + + LL GS + + + LH A+ H +++ +LL
Sbjct: 50 AKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLT 109
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
+ ++++KN +T LH+A H K ++ +G I N +G TPL A
Sbjct: 110 AFCSVHEKNQAGDTALHVAAALNHKKVAKILL----EAGADTTI--VNNAGQTPLETARY 163
Query: 607 WGYEGIARLL 616
+A LL
Sbjct: 164 HNNPEVALLL 173
Score = 46.4 bits (105), Expect = 5e-04
Identities = 33/107 (30%), Positives = 52/107 (48%)
Query: 780 LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLH 839
+ E LI ++ ++K T LH A+ + + +LL+ GAN+ A + A NT LH
Sbjct: 1 ITEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALH 60
Query: 840 DASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
A + + + ++LL L N T L VA HL+II L+
Sbjct: 61 LACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLL 107
>AL031177-6|CAI43131.1| 151|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 151
Score = 76.6 bits (180), Expect = 4e-13
Identities = 44/129 (34%), Positives = 68/129 (52%), Gaps = 6/129 (4%)
Query: 509 ETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNN 568
E++L S TD + +ALH+A S GH ++ LL G +N K+ +PLH+A +
Sbjct: 24 ESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASA 83
Query: 569 GHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNS 628
G VKA++ G+ +N N++G TPLH A+ IA +L+E G+ P ++
Sbjct: 84 GRDEIVKALL------GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH 137
Query: 629 YHKTAFDYA 637
Y TA A
Sbjct: 138 YEATAMHRA 146
Score = 66.1 bits (154), Expect = 5e-10
Identities = 30/81 (37%), Positives = 50/81 (61%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +D G + LH+A+ G+ IV+ LL G+++NA + N C+ LHYA+S+ + +ML
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 545 LHSGANINQKNIDKNTPLHLA 565
L GAN + K+ + T +H A
Sbjct: 126 LEGGANPDAKDHYEATAMHRA 146
Score = 58.4 bits (135), Expect = 1e-07
Identities = 37/88 (42%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T T +DS TALH A G IVE LL++G +N D S LH A+S G ++
Sbjct: 34 TRTDQDSR--TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKA 91
Query: 544 LLHSGANINQKNIDKNTPLHLAVN-NGH 570
LL GA +N N + TPLH A + N H
Sbjct: 92 LLGKGAQVNAVNQNGCTPLHYAASKNRH 119
Score = 58.4 bits (135), Expect = 1e-07
Identities = 33/82 (40%), Positives = 44/82 (53%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D G++ LH AA G DE L+ A VN N+ TPLH AA N+ + +L
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 821 LDNGANINAIDVARNTPLHDAS 842
L+ GAN +A D T +H A+
Sbjct: 126 LEGGANPDAKDHYEATAMHRAA 147
Score = 56.8 bits (131), Expect = 3e-07
Identities = 37/114 (32%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D + TALH+A G E L+ VN ++ +PLH+AA + +++ LL G
Sbjct: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL--AVAKD 876
A +NA++ TPLH A+ A +LL + + E TA+ A AKD
Sbjct: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKD 150
Score = 42.3 bits (95), Expect = 0.007
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Query: 780 LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLH 839
L+E ++ +++ ++ ++T LH A T ++ LL G +N D A +PLH
Sbjct: 19 LEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLH 78
Query: 840 DASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK-VHLTIIDLIDNYAN 891
A+ G K LL + +N T L A K H + L++ AN
Sbjct: 79 IAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN 131
>BC057225-1|AAH57225.1| 330|Homo sapiens ANKRD12 protein protein.
Length = 330
Score = 75.8 bits (178), Expect = 6e-13
Identities = 45/158 (28%), Positives = 81/158 (51%), Gaps = 9/158 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ R+ G T LH+A+I G V+ L+ +G+ +N D + LH A + G+ +V +L
Sbjct: 178 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 237
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +GA++N + +D +TPLH + ++GH VK ++ H G AN+ G P+ +A
Sbjct: 238 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLL---RHGGNPFQ---ANKHGERPVDVA 291
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRI 642
E + LL SY +++ +A N ++
Sbjct: 292 ET---EELELLLKREVPLSDDDESYTGSSYQFAGNAKL 326
Score = 66.9 bits (156), Expect = 3e-10
Identities = 34/93 (36%), Positives = 50/93 (53%)
Query: 794 VNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
VN RN++ +TPLH+AAI ++ L+ GAN+N D A TPLH+A G AKIL
Sbjct: 178 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 237
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
++ D+ + T L + H I+ L+
Sbjct: 238 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLL 270
Score = 60.9 bits (141), Expect = 2e-08
Identities = 39/123 (31%), Positives = 60/123 (48%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ RG + L+ GAN+N K+ TPLH A N G+ K +I +G +
Sbjct: 189 LHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIA----AGADV 244
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
N ++ +TPLH ++ G+ I +LL+ HG P N + + D A + +LK
Sbjct: 245 NTQGLDD--DTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKR 302
Query: 649 CTP 651
P
Sbjct: 303 EVP 305
Score = 54.0 bits (124), Expect = 2e-06
Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 4/130 (3%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFD---VNVCDSNGFTALHYAARYGLDEFCNI 786
A D ++ HP + ++KT S + VN + G T LH AA G +
Sbjct: 145 ARDNSPDSTPNHP-SQTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVKQVKE 203
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
LI ANVN ++ TPLH A V ++L+ GA++N + +TPLHD++ +G+
Sbjct: 204 LISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGH 263
Query: 847 IGAAKILLSY 856
K+LL +
Sbjct: 264 RDIVKLLLRH 273
Score = 47.2 bits (107), Expect = 3e-04
Identities = 26/67 (38%), Positives = 37/67 (55%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VNV D G+T LH A G + ILI A+VN + TPLH +A + +++L
Sbjct: 210 NVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKL 269
Query: 820 LLDNGAN 826
LL +G N
Sbjct: 270 LLRHGGN 276
>BC066643-1|AAH66643.1| 1202|Homo sapiens CASK interacting protein 2
protein.
Length = 1202
Score = 75.4 bits (177), Expect = 9e-13
Identities = 43/129 (33%), Positives = 72/129 (55%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN D++GF+ALH+AA G E +L+ +A V+ ++ PLH AA + +RL
Sbjct: 41 NVNYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRL 100
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL A +NA + PLH A++ G+ +++LL + + L+N +KT L +A +
Sbjct: 101 LLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGR 160
Query: 880 LTIIDLIDN 888
L + L+ N
Sbjct: 161 LKVAQLLLN 169
Score = 72.9 bits (171), Expect = 5e-12
Identities = 41/130 (31%), Positives = 70/130 (53%), Gaps = 6/130 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ G +ALH A++ G ++ LLE + ++ D N LHYA+ +G + +LL +
Sbjct: 45 QDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRA 104
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A +N ++D PLHLA GH + ++ +H +N A + TPL LA ++
Sbjct: 105 SAAVNAASLDGQIPLHLAAQYGHYEVSEMLL---QHQSNPCLVNKAKK---TPLDLACEF 158
Query: 608 GYEGIARLLI 617
G +A+LL+
Sbjct: 159 GRLKVAQLLL 168
Score = 69.3 bits (162), Expect = 6e-11
Identities = 40/128 (31%), Positives = 68/128 (53%), Gaps = 6/128 (4%)
Query: 518 INATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAI 577
+N D + SALH+A+ G ++ +LL + A ++ K+ + PLH A G L V+ +
Sbjct: 42 VNYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLL 101
Query: 578 IYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ + +N A+ G PLHLA+++G+ ++ +L++H S P L N KT D A
Sbjct: 102 LRASAA------VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLA 155
Query: 638 HNLRILQV 645
L+V
Sbjct: 156 CEFGRLKV 163
Score = 65.3 bits (152), Expect = 9e-10
Identities = 46/145 (31%), Positives = 69/145 (47%), Gaps = 2/145 (1%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +DS+G+ LH A+ G+ V LL + +NA L+ LH A+ GH V M
Sbjct: 74 TVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEM 133
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII--YFAEHSGRKININCANESGNTPL 601
LL +N N K TPL LA G L + ++ + + + + TPL
Sbjct: 134 LLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPL 193
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQ 626
HLA+K G+ + R L+ G E + Q
Sbjct: 194 HLAAKNGHREVIRQLLRAGIEINRQ 218
Score = 64.1 bits (149), Expect = 2e-09
Identities = 40/108 (37%), Positives = 57/108 (52%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
V++ DSNG LHYAA G E +L+ A VN + Q PLHLAA V +L
Sbjct: 75 VDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEML 134
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK 868
L + +N ++ A+ TPL A E G + A++LL+ + + LL K
Sbjct: 135 LQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAK 182
Score = 61.7 bits (143), Expect = 1e-08
Identities = 55/197 (27%), Positives = 90/197 (45%), Gaps = 15/197 (7%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G LH+A+ +G + E LL+ S + + + L A G V +LL+S +
Sbjct: 115 GQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCV 174
Query: 552 N------QKNIDKN--TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ D N TPLHLA NGH ++ ++ +G I IN ++G T LH
Sbjct: 175 ALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLL----RAG--IEINRQTKTG-TALHE 227
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
A+ +G + RLL+E G + +++N+Y++TA D + Q + L E I
Sbjct: 228 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVR 287
Query: 664 VKKISCESEKPTSLKLQ 680
K PT+L ++
Sbjct: 288 ALKDFWNLHDPTALNVR 304
Score = 50.8 bits (116), Expect = 2e-05
Identities = 30/75 (40%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 764 CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDN 823
CD N T LH AA+ G E L+ +N R K T LH AA+ KT V+RLLL+
Sbjct: 185 CDPNYTTPLHLAAKNGHREVIRQLLRAGIEIN-RQTKTGTALHEAALYGKTEVVRLLLEG 243
Query: 824 GANINAIDVARNTPL 838
G ++N + T L
Sbjct: 244 GVDVNIRNTYNQTAL 258
Score = 48.0 bits (109), Expect = 1e-04
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Query: 784 CNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASE 843
C L+ A C + TPLHLAA N VIR LL G IN T LH+A+
Sbjct: 173 CVALLEGEAKDPC-DPNYTTPLHLAAKNGHREVIRQLLRAGIEINR-QTKTGTALHEAAL 230
Query: 844 TGNIGAAKILLSYNPDITLLNATEKTALAV 873
G ++LL D+ + N +TAL +
Sbjct: 231 YGKTEVVRLLLEGGVDVNIRNTYNQTALDI 260
Score = 38.7 bits (86), Expect = 0.091
Identities = 24/96 (25%), Positives = 45/96 (46%)
Query: 791 RANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAA 850
R NVN ++ + LH AA+ +I LLL+ A ++ D PLH A+ G +
Sbjct: 39 RLNVNYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPV 98
Query: 851 KILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
++LL + + + + L +A H + +++
Sbjct: 99 RLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEML 134
Score = 33.9 bits (74), Expect = 2.6
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA---AINNKTVVIRLLLDNGAN 826
TALH AA YG E +L+ +VN RN QT L + + + I+ LL +
Sbjct: 223 TALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASG 282
Query: 827 INAIDVARN-TPLHDASETGNIGAAKIL--LSYNPD 859
I + ++ LHD + N+ A ++ L +PD
Sbjct: 283 ILKVRALKDFWNLHDPTAL-NVRAGDVITVLEQHPD 317
>AF451976-1|AAL49757.1| 1202|Homo sapiens cask-interacting protein 2
protein.
Length = 1202
Score = 75.4 bits (177), Expect = 9e-13
Identities = 43/129 (33%), Positives = 72/129 (55%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN D++GF+ALH+AA G E +L+ +A V+ ++ PLH AA + +RL
Sbjct: 41 NVNYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRL 100
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL A +NA + PLH A++ G+ +++LL + + L+N +KT L +A +
Sbjct: 101 LLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGR 160
Query: 880 LTIIDLIDN 888
L + L+ N
Sbjct: 161 LKVAQLLLN 169
Score = 72.9 bits (171), Expect = 5e-12
Identities = 41/130 (31%), Positives = 70/130 (53%), Gaps = 6/130 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D+ G +ALH A++ G ++ LLE + ++ D N LHYA+ +G + +LL +
Sbjct: 45 QDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRA 104
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
A +N ++D PLHLA GH + ++ +H +N A + TPL LA ++
Sbjct: 105 SAAVNAASLDGQIPLHLAAQYGHYEVSEMLL---QHQSNPCLVNKAKK---TPLDLACEF 158
Query: 608 GYEGIARLLI 617
G +A+LL+
Sbjct: 159 GRLKVAQLLL 168
Score = 69.3 bits (162), Expect = 6e-11
Identities = 40/128 (31%), Positives = 68/128 (53%), Gaps = 6/128 (4%)
Query: 518 INATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAI 577
+N D + SALH+A+ G ++ +LL + A ++ K+ + PLH A G L V+ +
Sbjct: 42 VNYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLL 101
Query: 578 IYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ + +N A+ G PLHLA+++G+ ++ +L++H S P L N KT D A
Sbjct: 102 LRASAA------VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLA 155
Query: 638 HNLRILQV 645
L+V
Sbjct: 156 CEFGRLKV 163
Score = 65.3 bits (152), Expect = 9e-10
Identities = 46/145 (31%), Positives = 69/145 (47%), Gaps = 2/145 (1%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T+ +DS+G+ LH A+ G+ V LL + +NA L+ LH A+ GH V M
Sbjct: 74 TVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEM 133
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII--YFAEHSGRKININCANESGNTPL 601
LL +N N K TPL LA G L + ++ + + + + TPL
Sbjct: 134 LLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPL 193
Query: 602 HLASKWGYEGIARLLIEHGSEPSLQ 626
HLA+K G+ + R L+ G E + Q
Sbjct: 194 HLAAKNGHREVIRQLLRAGIEINRQ 218
Score = 64.1 bits (149), Expect = 2e-09
Identities = 40/108 (37%), Positives = 57/108 (52%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
V++ DSNG LHYAA G E +L+ A VN + Q PLHLAA V +L
Sbjct: 75 VDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEML 134
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK 868
L + +N ++ A+ TPL A E G + A++LL+ + + LL K
Sbjct: 135 LQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAK 182
Score = 61.7 bits (143), Expect = 1e-08
Identities = 55/197 (27%), Positives = 90/197 (45%), Gaps = 15/197 (7%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G LH+A+ +G + E LL+ S + + + L A G V +LL+S +
Sbjct: 115 GQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCV 174
Query: 552 N------QKNIDKN--TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ D N TPLHLA NGH ++ ++ +G I IN ++G T LH
Sbjct: 175 ALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLL----RAG--IEINRQTKTG-TALHE 227
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
A+ +G + RLL+E G + +++N+Y++TA D + Q + L E I
Sbjct: 228 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVR 287
Query: 664 VKKISCESEKPTSLKLQ 680
K PT+L ++
Sbjct: 288 ALKDFWNLHDPTALNVR 304
Score = 50.8 bits (116), Expect = 2e-05
Identities = 30/75 (40%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 764 CDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDN 823
CD N T LH AA+ G E L+ +N R K T LH AA+ KT V+RLLL+
Sbjct: 185 CDPNYTTPLHLAAKNGHREVIRQLLRAGIEIN-RQTKTGTALHEAALYGKTEVVRLLLEG 243
Query: 824 GANINAIDVARNTPL 838
G ++N + T L
Sbjct: 244 GVDVNIRNTYNQTAL 258
Score = 48.0 bits (109), Expect = 1e-04
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Query: 784 CNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASE 843
C L+ A C + TPLHLAA N VIR LL G IN T LH+A+
Sbjct: 173 CVALLEGEAKDPC-DPNYTTPLHLAAKNGHREVIRQLLRAGIEINR-QTKTGTALHEAAL 230
Query: 844 TGNIGAAKILLSYNPDITLLNATEKTALAV 873
G ++LL D+ + N +TAL +
Sbjct: 231 YGKTEVVRLLLEGGVDVNIRNTYNQTALDI 260
Score = 38.7 bits (86), Expect = 0.091
Identities = 24/96 (25%), Positives = 45/96 (46%)
Query: 791 RANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAA 850
R NVN ++ + LH AA+ +I LLL+ A ++ D PLH A+ G +
Sbjct: 39 RLNVNYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPV 98
Query: 851 KILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
++LL + + + + L +A H + +++
Sbjct: 99 RLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEML 134
Score = 33.9 bits (74), Expect = 2.6
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLA---AINNKTVVIRLLLDNGAN 826
TALH AA YG E +L+ +VN RN QT L + + + I+ LL +
Sbjct: 223 TALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASG 282
Query: 827 INAIDVARN-TPLHDASETGNIGAAKIL--LSYNPD 859
I + ++ LHD + N+ A ++ L +PD
Sbjct: 283 ILKVRALKDFWNLHDPTAL-NVRAGDVITVLEQHPD 317
>AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase 2
protein.
Length = 1166
Score = 74.9 bits (176), Expect = 1e-12
Identities = 44/120 (36%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
Query: 757 TDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
T +VN S+G T LH AA Y + +L+ + A+V+ ++K PLH A
Sbjct: 198 TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY 257
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V LL+ +GA +NA+D+ + TPLH+A+ + +LLSY D TLLN K+A+ +A
Sbjct: 258 EVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLA 317
Score = 72.1 bits (169), Expect = 8e-12
Identities = 80/320 (25%), Positives = 147/320 (45%), Gaps = 32/320 (10%)
Query: 504 KATIVETLLEMGS--EINATDLN--ECSALHYASSRGHQNVLLMLLHSGANINQKNIDKN 559
KA VET+ ++ + +N D+ + + LH+A+ +V+ LL GA+++ K+
Sbjct: 501 KAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGL 560
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
PLH A + GH + ++ +H G +N+ A+ TPLH A+ G I +LL++H
Sbjct: 561 VPLHNACSYGHYEVAELLV---KH-GAVVNV--ADLWKFTPLHEAAAKGKYEICKLLLQH 614
Query: 620 GSEPSLQNSYHKTAFDYAH--NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G++P+ +N T D + I +L+ L + VKK+S P ++
Sbjct: 615 GADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLS----SPDNV 670
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ + S + NL++ E +L+ DV N + P N
Sbjct: 671 NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQ--HGADV-------NAQDKGGLIP---LHN 718
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCR 797
+ + + K +C VN D FT LH AA+ G + C +L+ + A+ +
Sbjct: 719 AASYGHVDVAALLIKYNAC----VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLK 774
Query: 798 NKKAQTPLHLAAINNKTVVI 817
N++ QTPL L + ++ + ++
Sbjct: 775 NQEGQTPLDLVSADDVSALL 794
Score = 70.5 bits (165), Expect = 2e-11
Identities = 44/116 (37%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Query: 761 VNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
VN D+ G T LH+AA +G + L+ N ANV R+ PLH A V+
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 108
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LLL +GA+ NA D TPLH+A+ G I +LL + + T+ N +TAL +A
Sbjct: 109 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 68.9 bits (161), Expect = 7e-11
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 2/123 (1%)
Query: 756 CTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
CT VN D G T LH+AA Y L+ + A+V+ ++K PLH A
Sbjct: 512 CTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGH 571
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
V LL+ +GA +N D+ + TPLH+A+ G K+LL + D T N T L +
Sbjct: 572 YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 631
Query: 874 AKD 876
KD
Sbjct: 632 VKD 634
Score = 65.7 bits (153), Expect = 7e-10
Identities = 42/125 (33%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 481 TCPTMTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQ 538
T ++ RD G T LH A+ + + ++VE LL+ G++++A D LH A S GH
Sbjct: 513 TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHY 572
Query: 539 NVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGN 598
V +L+ GA +N ++ K TPLH A G K ++ +K N GN
Sbjct: 573 EVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKK------NRDGN 626
Query: 599 TPLHL 603
TPL L
Sbjct: 627 TPLDL 631
Score = 64.5 bits (150), Expect = 2e-09
Identities = 79/293 (26%), Positives = 129/293 (44%), Gaps = 35/293 (11%)
Query: 517 EINATDL--NECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCV 574
++N+ D + + LH+A+ G ++V+ LL +GAN+ ++ PLH A + GH V
Sbjct: 48 KVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVV 107
Query: 575 KAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAF 634
++ + N N TPLH A+ G + +L++HG+EP+++N+ +TA
Sbjct: 108 NLLLRHGADPNARDNWNY------TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTAL 161
Query: 635 DYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASK 694
D A K+ ++ + S S EK +L L L + C ++
Sbjct: 162 DLAD-----PSAKAVLTGEYKKDELLES---ARSGNEEKMMAL-LTPLNVNCHASDGRKS 212
Query: 695 TIENLKLIERILRAISYGDVKLACFYMNIDYSAFI-APDKEKSNSLCHPLCECQYCKRKT 753
T +L A Y VK+ + + + A + A DK L H C + + T
Sbjct: 213 TPLHL--------AAGYNRVKIV--QLLLQHGADVHAKDKGDLVPL-HNACSYGHYE-VT 260
Query: 754 ESCTDFD--VNVCDSNGFTALHYAARYGLDEFCNILIFNRAN---VNCRNKKA 801
E VN D FT LH AA E C++L+ A+ +NC NK A
Sbjct: 261 ELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 313
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/122 (36%), Positives = 62/122 (50%), Gaps = 3/122 (2%)
Query: 760 DVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+VN D+ G T LH AA Y E L+ + A+VN ++K PLH AA V
Sbjct: 669 NVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVA 728
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL-AVAKD 876
LL+ A +NA D TPLH+A++ G +LL++ D TL N +T L V+ D
Sbjct: 729 ALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD 788
Query: 877 KV 878
V
Sbjct: 789 DV 790
Score = 64.1 bits (149), Expect = 2e-09
Identities = 36/112 (32%), Positives = 61/112 (54%), Gaps = 3/112 (2%)
Query: 770 TALHYAARYGLD---EFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
TALH AA + C +L+ AN+N + K+ TPLH+A+ V+ +++ + A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+NA+D T LH A+ G++ ++LLSY D +++ TAL + + V
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENV 477
Score = 60.5 bits (140), Expect = 3e-08
Identities = 86/383 (22%), Positives = 155/383 (40%), Gaps = 52/383 (13%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEIN--------ATDLNECSA---------- 528
+RD+ T LH A+I GK + LL+ G+E A DL + SA
Sbjct: 119 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKK 178
Query: 529 ---LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
L A S + ++ +L N + + K+TPLHLA + V+ ++ +H
Sbjct: 179 DELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLL---QHGA 235
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQV 645
+++ ++ PLH A +G+ + LL++HG+ + + + T A + ++V
Sbjct: 236 ---DVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEV 292
Query: 646 LKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERI 705
C+ L Y ++ ++C ++ L + T + + +
Sbjct: 293 ---CS-LLLSY----GADPTLLNCHNKSAIDL---------APTPQLKERLAYEFKGHSL 335
Query: 706 LRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESC-----TDFD 760
L+A DV +++++ F P + + H Y KRK + C +
Sbjct: 336 LQAAREADVTRIKKHLSLEMVNFKHP--QTHETALHCAAASPYPKRK-QICELLLRKGAN 392
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+N T LH A+ ++ +++ + A VN + QT LH AA RLL
Sbjct: 393 INEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLL 452
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L G + N I + T L +E
Sbjct: 453 LSYGCDPNIISLQGFTALQMGNE 475
Score = 60.1 bits (139), Expect = 3e-08
Identities = 36/117 (30%), Positives = 63/117 (53%), Gaps = 3/117 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCR--NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDV 832
+AR G +E L+ NVNC + + TPLHLAA N+ +++LLL +GA+++A D
Sbjct: 184 SARSGNEEKMMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDK 242
Query: 833 ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
PLH+A G+ ++L+ + + ++ + T L A K + + L+ +Y
Sbjct: 243 GDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSY 299
Score = 58.4 bits (135), Expect = 1e-07
Identities = 44/123 (35%), Positives = 62/123 (50%), Gaps = 10/123 (8%)
Query: 485 MTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
+ SRD+ G T LH A+ G+ +VE LL+ G+ + A D LH A S GH V+
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 108
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPL 601
+LL GA+ N ++ TPLH A G + C+ + + AE + R N G T L
Sbjct: 109 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIR-------NTDGRTAL 161
Query: 602 HLA 604
LA
Sbjct: 162 DLA 164
Score = 56.8 bits (131), Expect = 3e-07
Identities = 77/365 (21%), Positives = 150/365 (41%), Gaps = 24/365 (6%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
L + +A+D + + LH A+ ++ +LL GA+++ K+ PLH A + GH
Sbjct: 197 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGH 256
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH 630
+ ++ +H +N + TPLH A+ + LL+ +G++P+L N ++
Sbjct: 257 YEVTELLV---KHGA---CVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHN 310
Query: 631 KTAFDYAHNLRILQVL--KSCTPNLFEYIHITS-SEVKK-ISCESEKPTSLKLQNLTLKC 686
K+A D A ++ + L + +L + + +KK +S E + L C
Sbjct: 311 KSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHC 370
Query: 687 SDTNDASKTIENLKLIERILRAIS------YGDVKLACFYMNIDYSAFIAPDKEKSNSLC 740
+ + K + +L+ R I+ + +A + D + + K N+L
Sbjct: 371 AAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALD 430
Query: 741 H----PLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC 796
+ L YC ++C CD N + + A +E N+ + ++
Sbjct: 431 NLGQTSLHRAAYCGH-LQTCRLLLSYGCDPNIISLQGFTALQMGNE--NVQQLLQEGISL 487
Query: 797 RNKKAQTP-LHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLS 855
N +A L A + V +L N I+ ++TPLH A+ + + LL
Sbjct: 488 GNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQ 547
Query: 856 YNPDI 860
+ D+
Sbjct: 548 HGADV 552
Score = 56.8 bits (131), Expect = 3e-07
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 488 RDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
RD+ G T LH+A+ + + E LL+ G+++NA D LH A+S GH +V +L+
Sbjct: 673 RDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLI 732
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPLHLA 604
A +N + TPLH A G C + + A+ + N+ G TPL L
Sbjct: 733 KYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPT-------LKNQEGQTPLDLV 785
Query: 605 S 605
S
Sbjct: 786 S 786
Score = 54.8 bits (126), Expect = 1e-06
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ + V LL GA++N ++ PLH A + GH+ +I +
Sbjct: 683 LHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKY------NA 736
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
+N ++ TPLH A++ G + LL+ HG++P+L+N +T D + +L +
Sbjct: 737 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTA 796
Query: 649 CTP 651
P
Sbjct: 797 AMP 799
Score = 52.8 bits (121), Expect = 5e-06
Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 793 NVNCRNKKAQ--TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAA 850
+VNCR+ + + TPLH AA N+ V+ LL +GA+++A D PLH+A G+ A
Sbjct: 516 SVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVA 575
Query: 851 KILLSYNPDITLLNATEKTAL--AVAKDKVHL 880
++L+ + + + + + T L A AK K +
Sbjct: 576 ELLVKHGAVVNVADLWKFTPLHEAAAKGKYEI 607
Score = 49.6 bits (113), Expect = 5e-05
Identities = 26/80 (32%), Positives = 43/80 (53%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D GL LH A+ +G + L++ + +NATD + LH A+ +G + +L
Sbjct: 705 VNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALL 764
Query: 545 LHSGANINQKNIDKNTPLHL 564
L GA+ KN + TPL L
Sbjct: 765 LAHGADPTLKNQEGQTPLDL 784
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V D G LH A +G E N+L+ + A+ N R+ TPLH AAI K V +
Sbjct: 83 NVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIV 142
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL-SYNPDITLLNA 865
LL +GA RNT A + + A +L Y D L +A
Sbjct: 143 LLQHGAE----PTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185
Score = 44.0 bits (99), Expect = 0.002
Identities = 38/151 (25%), Positives = 72/151 (47%), Gaps = 21/151 (13%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
LT LHVAS +VE +++ +++NA D ++LH A+ GH +LL G + N
Sbjct: 401 LTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 460
Query: 553 QKNIDKNTPLHLAVNN-----------GHLHCVKAIIYFAE----HSGRKI----NINCA 593
++ T L + N G+ + ++ A+ + +K+ ++NC
Sbjct: 461 IISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCR 520
Query: 594 NESG--NTPLHLASKWGYEGIARLLIEHGSE 622
+ G +TPLH A+ + + L++HG++
Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGAD 551
Score = 39.5 bits (88), Expect = 0.052
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 802 QTPLHLAAIN---NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
+T LH AA + + + LLL GANIN TPLH ASE + ++++ +
Sbjct: 365 ETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEA 424
Query: 859 DITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
+ L+ +T+L A HL L+ +Y
Sbjct: 425 KVNALDNLGQTSLHRAAYCGHLQTCRLLLSY 455
>AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein.
Length = 1166
Score = 74.9 bits (176), Expect = 1e-12
Identities = 44/120 (36%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
Query: 757 TDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
T +VN S+G T LH AA Y + +L+ + A+V+ ++K PLH A
Sbjct: 198 TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY 257
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V LL+ +GA +NA+D+ + TPLH+A+ + +LLSY D TLLN K+A+ +A
Sbjct: 258 EVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLA 317
Score = 72.1 bits (169), Expect = 8e-12
Identities = 80/320 (25%), Positives = 147/320 (45%), Gaps = 32/320 (10%)
Query: 504 KATIVETLLEMGS--EINATDLN--ECSALHYASSRGHQNVLLMLLHSGANINQKNIDKN 559
KA VET+ ++ + +N D+ + + LH+A+ +V+ LL GA+++ K+
Sbjct: 501 KAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGL 560
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
PLH A + GH + ++ +H G +N+ A+ TPLH A+ G I +LL++H
Sbjct: 561 VPLHNACSYGHYEVAELLV---KH-GAVVNV--ADLWKFTPLHEAAAKGKYEICKLLLQH 614
Query: 620 GSEPSLQNSYHKTAFDYAH--NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G++P+ +N T D + I +L+ L + VKK+S P ++
Sbjct: 615 GADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLS----SPDNV 670
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ + S + NL++ E +L+ DV N + P N
Sbjct: 671 NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQ--HGADV-------NAQDKGGLIP---LHN 718
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCR 797
+ + + K +C VN D FT LH AA+ G + C +L+ + A+ +
Sbjct: 719 AASYGHVDVAALLIKYNAC----VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLK 774
Query: 798 NKKAQTPLHLAAINNKTVVI 817
N++ QTPL L + ++ + ++
Sbjct: 775 NQEGQTPLDLVSADDVSALL 794
Score = 70.5 bits (165), Expect = 2e-11
Identities = 44/116 (37%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Query: 761 VNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
VN D+ G T LH+AA +G + L+ N ANV R+ PLH A V+
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 108
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LLL +GA+ NA D TPLH+A+ G I +LL + + T+ N +TAL +A
Sbjct: 109 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 68.9 bits (161), Expect = 7e-11
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 2/123 (1%)
Query: 756 CTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
CT VN D G T LH+AA Y L+ + A+V+ ++K PLH A
Sbjct: 512 CTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGH 571
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
V LL+ +GA +N D+ + TPLH+A+ G K+LL + D T N T L +
Sbjct: 572 YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 631
Query: 874 AKD 876
KD
Sbjct: 632 VKD 634
Score = 65.7 bits (153), Expect = 7e-10
Identities = 42/125 (33%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 481 TCPTMTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQ 538
T ++ RD G T LH A+ + + ++VE LL+ G++++A D LH A S GH
Sbjct: 513 TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHY 572
Query: 539 NVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGN 598
V +L+ GA +N ++ K TPLH A G K ++ +K N GN
Sbjct: 573 EVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKK------NRDGN 626
Query: 599 TPLHL 603
TPL L
Sbjct: 627 TPLDL 631
Score = 64.5 bits (150), Expect = 2e-09
Identities = 79/293 (26%), Positives = 129/293 (44%), Gaps = 35/293 (11%)
Query: 517 EINATDL--NECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCV 574
++N+ D + + LH+A+ G ++V+ LL +GAN+ ++ PLH A + GH V
Sbjct: 48 KVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVV 107
Query: 575 KAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAF 634
++ + N N TPLH A+ G + +L++HG+EP+++N+ +TA
Sbjct: 108 NLLLRHGADPNARDNWNY------TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTAL 161
Query: 635 DYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASK 694
D A K+ ++ + S S EK +L L L + C ++
Sbjct: 162 DLAD-----PSAKAVLTGEYKKDELLES---ARSGNEEKMMAL-LTPLNVNCHASDGRKS 212
Query: 695 TIENLKLIERILRAISYGDVKLACFYMNIDYSAFI-APDKEKSNSLCHPLCECQYCKRKT 753
T +L A Y VK+ + + + A + A DK L H C + + T
Sbjct: 213 TPLHL--------AAGYNRVKIV--QLLLQHGADVHAKDKGDLVPL-HNACSYGHYE-VT 260
Query: 754 ESCTDFD--VNVCDSNGFTALHYAARYGLDEFCNILIFNRAN---VNCRNKKA 801
E VN D FT LH AA E C++L+ A+ +NC NK A
Sbjct: 261 ELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 313
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/122 (36%), Positives = 62/122 (50%), Gaps = 3/122 (2%)
Query: 760 DVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+VN D+ G T LH AA Y E L+ + A+VN ++K PLH AA V
Sbjct: 669 NVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVA 728
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL-AVAKD 876
LL+ A +NA D TPLH+A++ G +LL++ D TL N +T L V+ D
Sbjct: 729 ALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD 788
Query: 877 KV 878
V
Sbjct: 789 DV 790
Score = 64.1 bits (149), Expect = 2e-09
Identities = 36/112 (32%), Positives = 61/112 (54%), Gaps = 3/112 (2%)
Query: 770 TALHYAARYGLD---EFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
TALH AA + C +L+ AN+N + K+ TPLH+A+ V+ +++ + A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+NA+D T LH A+ G++ ++LLSY D +++ TAL + + V
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENV 477
Score = 60.5 bits (140), Expect = 3e-08
Identities = 86/383 (22%), Positives = 155/383 (40%), Gaps = 52/383 (13%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEIN--------ATDLNECSA---------- 528
+RD+ T LH A+I GK + LL+ G+E A DL + SA
Sbjct: 119 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKK 178
Query: 529 ---LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
L A S + ++ +L N + + K+TPLHLA + V+ ++ +H
Sbjct: 179 DELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLL---QHGA 235
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQV 645
+++ ++ PLH A +G+ + LL++HG+ + + + T A + ++V
Sbjct: 236 ---DVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEV 292
Query: 646 LKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERI 705
C+ L Y ++ ++C ++ L + T + + +
Sbjct: 293 ---CS-LLLSY----GADPTLLNCHNKSAIDL---------APTPQLKERLAYEFKGHSL 335
Query: 706 LRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESC-----TDFD 760
L+A DV +++++ F P + + H Y KRK + C +
Sbjct: 336 LQAAREADVTRIKKHLSLEMVNFKHP--QTHETALHCAAASPYPKRK-QICELLLRKGAN 392
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+N T LH A+ ++ +++ + A VN + QT LH AA RLL
Sbjct: 393 INEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLL 452
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L G + N I + T L +E
Sbjct: 453 LSYGCDPNIISLQGFTALQMGNE 475
Score = 60.1 bits (139), Expect = 3e-08
Identities = 36/117 (30%), Positives = 63/117 (53%), Gaps = 3/117 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCR--NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDV 832
+AR G +E L+ NVNC + + TPLHLAA N+ +++LLL +GA+++A D
Sbjct: 184 SARSGNEEKMMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDK 242
Query: 833 ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
PLH+A G+ ++L+ + + ++ + T L A K + + L+ +Y
Sbjct: 243 GDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSY 299
Score = 58.4 bits (135), Expect = 1e-07
Identities = 44/123 (35%), Positives = 62/123 (50%), Gaps = 10/123 (8%)
Query: 485 MTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
+ SRD+ G T LH A+ G+ +VE LL+ G+ + A D LH A S GH V+
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 108
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPL 601
+LL GA+ N ++ TPLH A G + C+ + + AE + R N G T L
Sbjct: 109 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIR-------NTDGRTAL 161
Query: 602 HLA 604
LA
Sbjct: 162 DLA 164
Score = 56.8 bits (131), Expect = 3e-07
Identities = 77/365 (21%), Positives = 150/365 (41%), Gaps = 24/365 (6%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
L + +A+D + + LH A+ ++ +LL GA+++ K+ PLH A + GH
Sbjct: 197 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGH 256
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH 630
+ ++ +H +N + TPLH A+ + LL+ +G++P+L N ++
Sbjct: 257 YEVTELLV---KHGA---CVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHN 310
Query: 631 KTAFDYAHNLRILQVL--KSCTPNLFEYIHITS-SEVKK-ISCESEKPTSLKLQNLTLKC 686
K+A D A ++ + L + +L + + +KK +S E + L C
Sbjct: 311 KSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHC 370
Query: 687 SDTNDASKTIENLKLIERILRAIS------YGDVKLACFYMNIDYSAFIAPDKEKSNSLC 740
+ + K + +L+ R I+ + +A + D + + K N+L
Sbjct: 371 AAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALD 430
Query: 741 H----PLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC 796
+ L YC ++C CD N + + A +E N+ + ++
Sbjct: 431 NLGQTSLHRAAYCGH-LQTCRLLLSYGCDPNIISLQGFTALQMGNE--NVQQLLQEGISL 487
Query: 797 RNKKAQTP-LHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLS 855
N +A L A + V +L N I+ ++TPLH A+ + + LL
Sbjct: 488 GNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQ 547
Query: 856 YNPDI 860
+ D+
Sbjct: 548 HGADV 552
Score = 56.8 bits (131), Expect = 3e-07
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 488 RDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
RD+ G T LH+A+ + + E LL+ G+++NA D LH A+S GH +V +L+
Sbjct: 673 RDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLI 732
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPLHLA 604
A +N + TPLH A G C + + A+ + N+ G TPL L
Sbjct: 733 KYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPT-------LKNQEGQTPLDLV 785
Query: 605 S 605
S
Sbjct: 786 S 786
Score = 54.8 bits (126), Expect = 1e-06
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ + V LL GA++N ++ PLH A + GH+ +I +
Sbjct: 683 LHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKY------NA 736
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
+N ++ TPLH A++ G + LL+ HG++P+L+N +T D + +L +
Sbjct: 737 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTA 796
Query: 649 CTP 651
P
Sbjct: 797 AMP 799
Score = 52.8 bits (121), Expect = 5e-06
Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 793 NVNCRNKKAQ--TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAA 850
+VNCR+ + + TPLH AA N+ V+ LL +GA+++A D PLH+A G+ A
Sbjct: 516 SVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVA 575
Query: 851 KILLSYNPDITLLNATEKTAL--AVAKDKVHL 880
++L+ + + + + + T L A AK K +
Sbjct: 576 ELLVKHGAVVNVADLWKFTPLHEAAAKGKYEI 607
Score = 49.6 bits (113), Expect = 5e-05
Identities = 26/80 (32%), Positives = 43/80 (53%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D GL LH A+ +G + L++ + +NATD + LH A+ +G + +L
Sbjct: 705 VNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALL 764
Query: 545 LHSGANINQKNIDKNTPLHL 564
L GA+ KN + TPL L
Sbjct: 765 LAHGADPTLKNQEGQTPLDL 784
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V D G LH A +G E N+L+ + A+ N R+ TPLH AAI K V +
Sbjct: 83 NVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIV 142
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL-SYNPDITLLNA 865
LL +GA RNT A + + A +L Y D L +A
Sbjct: 143 LLQHGAE----PTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185
Score = 44.0 bits (99), Expect = 0.002
Identities = 38/151 (25%), Positives = 72/151 (47%), Gaps = 21/151 (13%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
LT LHVAS +VE +++ +++NA D ++LH A+ GH +LL G + N
Sbjct: 401 LTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 460
Query: 553 QKNIDKNTPLHLAVNN-----------GHLHCVKAIIYFAE----HSGRKI----NINCA 593
++ T L + N G+ + ++ A+ + +K+ ++NC
Sbjct: 461 IISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCR 520
Query: 594 NESG--NTPLHLASKWGYEGIARLLIEHGSE 622
+ G +TPLH A+ + + L++HG++
Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGAD 551
Score = 39.5 bits (88), Expect = 0.052
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 802 QTPLHLAAIN---NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
+T LH AA + + + LLL GANIN TPLH ASE + ++++ +
Sbjct: 365 ETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEA 424
Query: 859 DITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
+ L+ +T+L A HL L+ +Y
Sbjct: 425 KVNALDNLGQTSLHRAAYCGHLQTCRLLLSY 455
>AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein.
Length = 1166
Score = 74.9 bits (176), Expect = 1e-12
Identities = 44/120 (36%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
Query: 757 TDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
T +VN S+G T LH AA Y + +L+ + A+V+ ++K PLH A
Sbjct: 198 TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY 257
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V LL+ +GA +NA+D+ + TPLH+A+ + +LLSY D TLLN K+A+ +A
Sbjct: 258 EVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLA 317
Score = 72.1 bits (169), Expect = 8e-12
Identities = 80/320 (25%), Positives = 147/320 (45%), Gaps = 32/320 (10%)
Query: 504 KATIVETLLEMGS--EINATDLN--ECSALHYASSRGHQNVLLMLLHSGANINQKNIDKN 559
KA VET+ ++ + +N D+ + + LH+A+ +V+ LL GA+++ K+
Sbjct: 501 KAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGL 560
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
PLH A + GH + ++ +H G +N+ A+ TPLH A+ G I +LL++H
Sbjct: 561 VPLHNACSYGHYEVAELLV---KH-GAVVNV--ADLWKFTPLHEAAAKGKYEICKLLLQH 614
Query: 620 GSEPSLQNSYHKTAFDYAH--NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G++P+ +N T D + I +L+ L + VKK+S P ++
Sbjct: 615 GADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLS----SPDNV 670
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ + S + NL++ E +L+ DV N + P N
Sbjct: 671 NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQ--HGADV-------NAQDKGGLIP---LHN 718
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCR 797
+ + + K +C VN D FT LH AA+ G + C +L+ + A+ +
Sbjct: 719 AASYGHVDVAALLIKYNAC----VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLK 774
Query: 798 NKKAQTPLHLAAINNKTVVI 817
N++ QTPL L + ++ + ++
Sbjct: 775 NQEGQTPLDLVSADDVSALL 794
Score = 70.5 bits (165), Expect = 2e-11
Identities = 44/116 (37%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Query: 761 VNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
VN D+ G T LH+AA +G + L+ N ANV R+ PLH A V+
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 108
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LLL +GA+ NA D TPLH+A+ G I +LL + + T+ N +TAL +A
Sbjct: 109 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 68.9 bits (161), Expect = 7e-11
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 2/123 (1%)
Query: 756 CTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
CT VN D G T LH+AA Y L+ + A+V+ ++K PLH A
Sbjct: 512 CTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGH 571
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
V LL+ +GA +N D+ + TPLH+A+ G K+LL + D T N T L +
Sbjct: 572 YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 631
Query: 874 AKD 876
KD
Sbjct: 632 VKD 634
Score = 65.7 bits (153), Expect = 7e-10
Identities = 42/125 (33%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 481 TCPTMTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQ 538
T ++ RD G T LH A+ + + ++VE LL+ G++++A D LH A S GH
Sbjct: 513 TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHY 572
Query: 539 NVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGN 598
V +L+ GA +N ++ K TPLH A G K ++ +K N GN
Sbjct: 573 EVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKK------NRDGN 626
Query: 599 TPLHL 603
TPL L
Sbjct: 627 TPLDL 631
Score = 64.5 bits (150), Expect = 2e-09
Identities = 79/293 (26%), Positives = 129/293 (44%), Gaps = 35/293 (11%)
Query: 517 EINATDL--NECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCV 574
++N+ D + + LH+A+ G ++V+ LL +GAN+ ++ PLH A + GH V
Sbjct: 48 KVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVV 107
Query: 575 KAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAF 634
++ + N N TPLH A+ G + +L++HG+EP+++N+ +TA
Sbjct: 108 NLLLRHGADPNARDNWNY------TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTAL 161
Query: 635 DYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASK 694
D A K+ ++ + S S EK +L L L + C ++
Sbjct: 162 DLAD-----PSAKAVLTGEYKKDELLES---ARSGNEEKMMAL-LTPLNVNCHASDGRKS 212
Query: 695 TIENLKLIERILRAISYGDVKLACFYMNIDYSAFI-APDKEKSNSLCHPLCECQYCKRKT 753
T +L A Y VK+ + + + A + A DK L H C + + T
Sbjct: 213 TPLHL--------AAGYNRVKIV--QLLLQHGADVHAKDKGDLVPL-HNACSYGHYE-VT 260
Query: 754 ESCTDFD--VNVCDSNGFTALHYAARYGLDEFCNILIFNRAN---VNCRNKKA 801
E VN D FT LH AA E C++L+ A+ +NC NK A
Sbjct: 261 ELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 313
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/122 (36%), Positives = 62/122 (50%), Gaps = 3/122 (2%)
Query: 760 DVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+VN D+ G T LH AA Y E L+ + A+VN ++K PLH AA V
Sbjct: 669 NVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVA 728
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL-AVAKD 876
LL+ A +NA D TPLH+A++ G +LL++ D TL N +T L V+ D
Sbjct: 729 ALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD 788
Query: 877 KV 878
V
Sbjct: 789 DV 790
Score = 64.1 bits (149), Expect = 2e-09
Identities = 36/112 (32%), Positives = 61/112 (54%), Gaps = 3/112 (2%)
Query: 770 TALHYAARYGLD---EFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
TALH AA + C +L+ AN+N + K+ TPLH+A+ V+ +++ + A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+NA+D T LH A+ G++ ++LLSY D +++ TAL + + V
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENV 477
Score = 60.5 bits (140), Expect = 3e-08
Identities = 86/383 (22%), Positives = 155/383 (40%), Gaps = 52/383 (13%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEIN--------ATDLNECSA---------- 528
+RD+ T LH A+I GK + LL+ G+E A DL + SA
Sbjct: 119 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKK 178
Query: 529 ---LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
L A S + ++ +L N + + K+TPLHLA + V+ ++ +H
Sbjct: 179 DELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLL---QHGA 235
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQV 645
+++ ++ PLH A +G+ + LL++HG+ + + + T A + ++V
Sbjct: 236 ---DVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEV 292
Query: 646 LKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERI 705
C+ L Y ++ ++C ++ L + T + + +
Sbjct: 293 ---CS-LLLSY----GADPTLLNCHNKSAIDL---------APTPQLKERLAYEFKGHSL 335
Query: 706 LRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESC-----TDFD 760
L+A DV +++++ F P + + H Y KRK + C +
Sbjct: 336 LQAAREADVTRIKKHLSLEMVNFKHP--QTHETALHCAAASPYPKRK-QICELLLRKGAN 392
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+N T LH A+ ++ +++ + A VN + QT LH AA RLL
Sbjct: 393 INEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLL 452
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L G + N I + T L +E
Sbjct: 453 LSYGCDPNIISLQGFTALQMGNE 475
Score = 60.1 bits (139), Expect = 3e-08
Identities = 36/117 (30%), Positives = 63/117 (53%), Gaps = 3/117 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCR--NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDV 832
+AR G +E L+ NVNC + + TPLHLAA N+ +++LLL +GA+++A D
Sbjct: 184 SARSGNEEKMMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDK 242
Query: 833 ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
PLH+A G+ ++L+ + + ++ + T L A K + + L+ +Y
Sbjct: 243 GDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSY 299
Score = 58.4 bits (135), Expect = 1e-07
Identities = 44/123 (35%), Positives = 62/123 (50%), Gaps = 10/123 (8%)
Query: 485 MTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
+ SRD+ G T LH A+ G+ +VE LL+ G+ + A D LH A S GH V+
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 108
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPL 601
+LL GA+ N ++ TPLH A G + C+ + + AE + R N G T L
Sbjct: 109 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIR-------NTDGRTAL 161
Query: 602 HLA 604
LA
Sbjct: 162 DLA 164
Score = 56.8 bits (131), Expect = 3e-07
Identities = 77/365 (21%), Positives = 150/365 (41%), Gaps = 24/365 (6%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
L + +A+D + + LH A+ ++ +LL GA+++ K+ PLH A + GH
Sbjct: 197 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGH 256
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH 630
+ ++ +H +N + TPLH A+ + LL+ +G++P+L N ++
Sbjct: 257 YEVTELLV---KHGA---CVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHN 310
Query: 631 KTAFDYAHNLRILQVL--KSCTPNLFEYIHITS-SEVKK-ISCESEKPTSLKLQNLTLKC 686
K+A D A ++ + L + +L + + +KK +S E + L C
Sbjct: 311 KSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHC 370
Query: 687 SDTNDASKTIENLKLIERILRAIS------YGDVKLACFYMNIDYSAFIAPDKEKSNSLC 740
+ + K + +L+ R I+ + +A + D + + K N+L
Sbjct: 371 AAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALD 430
Query: 741 H----PLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC 796
+ L YC ++C CD N + + A +E N+ + ++
Sbjct: 431 NLGQTSLHRAAYCGH-LQTCRLLLSYGCDPNIISLQGFTALQMGNE--NVQQLLQEGISL 487
Query: 797 RNKKAQTP-LHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLS 855
N +A L A + V +L N I+ ++TPLH A+ + + LL
Sbjct: 488 GNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQ 547
Query: 856 YNPDI 860
+ D+
Sbjct: 548 HGADV 552
Score = 56.8 bits (131), Expect = 3e-07
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 488 RDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
RD+ G T LH+A+ + + E LL+ G+++NA D LH A+S GH +V +L+
Sbjct: 673 RDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLI 732
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPLHLA 604
A +N + TPLH A G C + + A+ + N+ G TPL L
Sbjct: 733 KYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPT-------LKNQEGQTPLDLV 785
Query: 605 S 605
S
Sbjct: 786 S 786
Score = 54.8 bits (126), Expect = 1e-06
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ + V LL GA++N ++ PLH A + GH+ +I +
Sbjct: 683 LHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKY------NA 736
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
+N ++ TPLH A++ G + LL+ HG++P+L+N +T D + +L +
Sbjct: 737 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTA 796
Query: 649 CTP 651
P
Sbjct: 797 AMP 799
Score = 52.8 bits (121), Expect = 5e-06
Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 793 NVNCRNKKAQ--TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAA 850
+VNCR+ + + TPLH AA N+ V+ LL +GA+++A D PLH+A G+ A
Sbjct: 516 SVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVA 575
Query: 851 KILLSYNPDITLLNATEKTAL--AVAKDKVHL 880
++L+ + + + + + T L A AK K +
Sbjct: 576 ELLVKHGAVVNVADLWKFTPLHEAAAKGKYEI 607
Score = 49.6 bits (113), Expect = 5e-05
Identities = 26/80 (32%), Positives = 43/80 (53%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D GL LH A+ +G + L++ + +NATD + LH A+ +G + +L
Sbjct: 705 VNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALL 764
Query: 545 LHSGANINQKNIDKNTPLHL 564
L GA+ KN + TPL L
Sbjct: 765 LAHGADPTLKNQEGQTPLDL 784
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V D G LH A +G E N+L+ + A+ N R+ TPLH AAI K V +
Sbjct: 83 NVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIV 142
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL-SYNPDITLLNA 865
LL +GA RNT A + + A +L Y D L +A
Sbjct: 143 LLQHGAE----PTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185
Score = 44.0 bits (99), Expect = 0.002
Identities = 38/151 (25%), Positives = 72/151 (47%), Gaps = 21/151 (13%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
LT LHVAS +VE +++ +++NA D ++LH A+ GH +LL G + N
Sbjct: 401 LTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 460
Query: 553 QKNIDKNTPLHLAVNN-----------GHLHCVKAIIYFAE----HSGRKI----NINCA 593
++ T L + N G+ + ++ A+ + +K+ ++NC
Sbjct: 461 IISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCR 520
Query: 594 NESG--NTPLHLASKWGYEGIARLLIEHGSE 622
+ G +TPLH A+ + + L++HG++
Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGAD 551
Score = 39.5 bits (88), Expect = 0.052
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 802 QTPLHLAAIN---NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
+T LH AA + + + LLL GANIN TPLH ASE + ++++ +
Sbjct: 365 ETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEA 424
Query: 859 DITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
+ L+ +T+L A HL L+ +Y
Sbjct: 425 KVNALDNLGQTSLHRAAYCGHLQTCRLLLSY 455
>AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein.
Length = 1166
Score = 74.9 bits (176), Expect = 1e-12
Identities = 44/120 (36%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
Query: 757 TDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
T +VN S+G T LH AA Y + +L+ + A+V+ ++K PLH A
Sbjct: 198 TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY 257
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V LL+ +GA +NA+D+ + TPLH+A+ + +LLSY D TLLN K+A+ +A
Sbjct: 258 EVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLA 317
Score = 72.1 bits (169), Expect = 8e-12
Identities = 80/320 (25%), Positives = 147/320 (45%), Gaps = 32/320 (10%)
Query: 504 KATIVETLLEMGS--EINATDLN--ECSALHYASSRGHQNVLLMLLHSGANINQKNIDKN 559
KA VET+ ++ + +N D+ + + LH+A+ +V+ LL GA+++ K+
Sbjct: 501 KAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGL 560
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
PLH A + GH + ++ +H G +N+ A+ TPLH A+ G I +LL++H
Sbjct: 561 VPLHNACSYGHYEVAELLV---KH-GAVVNV--ADLWKFTPLHEAAAKGKYEICKLLLQH 614
Query: 620 GSEPSLQNSYHKTAFDYAH--NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G++P+ +N T D + I +L+ L + VKK+S P ++
Sbjct: 615 GADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLS----SPDNV 670
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ + S + NL++ E +L+ DV N + P N
Sbjct: 671 NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQ--HGADV-------NAQDKGGLIP---LHN 718
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCR 797
+ + + K +C VN D FT LH AA+ G + C +L+ + A+ +
Sbjct: 719 AASYGHVDVAALLIKYNAC----VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLK 774
Query: 798 NKKAQTPLHLAAINNKTVVI 817
N++ QTPL L + ++ + ++
Sbjct: 775 NQEGQTPLDLVSADDVSALL 794
Score = 70.5 bits (165), Expect = 2e-11
Identities = 44/116 (37%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Query: 761 VNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
VN D+ G T LH+AA +G + L+ N ANV R+ PLH A V+
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 108
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LLL +GA+ NA D TPLH+A+ G I +LL + + T+ N +TAL +A
Sbjct: 109 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 68.9 bits (161), Expect = 7e-11
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 2/123 (1%)
Query: 756 CTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
CT VN D G T LH+AA Y L+ + A+V+ ++K PLH A
Sbjct: 512 CTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGH 571
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
V LL+ +GA +N D+ + TPLH+A+ G K+LL + D T N T L +
Sbjct: 572 YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 631
Query: 874 AKD 876
KD
Sbjct: 632 VKD 634
Score = 65.7 bits (153), Expect = 7e-10
Identities = 42/125 (33%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 481 TCPTMTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQ 538
T ++ RD G T LH A+ + + ++VE LL+ G++++A D LH A S GH
Sbjct: 513 TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHY 572
Query: 539 NVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGN 598
V +L+ GA +N ++ K TPLH A G K ++ +K N GN
Sbjct: 573 EVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKK------NRDGN 626
Query: 599 TPLHL 603
TPL L
Sbjct: 627 TPLDL 631
Score = 64.5 bits (150), Expect = 2e-09
Identities = 79/293 (26%), Positives = 129/293 (44%), Gaps = 35/293 (11%)
Query: 517 EINATDL--NECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCV 574
++N+ D + + LH+A+ G ++V+ LL +GAN+ ++ PLH A + GH V
Sbjct: 48 KVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVV 107
Query: 575 KAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAF 634
++ + N N TPLH A+ G + +L++HG+EP+++N+ +TA
Sbjct: 108 NLLLRHGADPNARDNWNY------TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTAL 161
Query: 635 DYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASK 694
D A K+ ++ + S S EK +L L L + C ++
Sbjct: 162 DLAD-----PSAKAVLTGEYKKDELLES---ARSGNEEKMMAL-LTPLNVNCHASDGRKS 212
Query: 695 TIENLKLIERILRAISYGDVKLACFYMNIDYSAFI-APDKEKSNSLCHPLCECQYCKRKT 753
T +L A Y VK+ + + + A + A DK L H C + + T
Sbjct: 213 TPLHL--------AAGYNRVKIV--QLLLQHGADVHAKDKGDLVPL-HNACSYGHYE-VT 260
Query: 754 ESCTDFD--VNVCDSNGFTALHYAARYGLDEFCNILIFNRAN---VNCRNKKA 801
E VN D FT LH AA E C++L+ A+ +NC NK A
Sbjct: 261 ELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 313
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/122 (36%), Positives = 62/122 (50%), Gaps = 3/122 (2%)
Query: 760 DVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+VN D+ G T LH AA Y E L+ + A+VN ++K PLH AA V
Sbjct: 669 NVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVA 728
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL-AVAKD 876
LL+ A +NA D TPLH+A++ G +LL++ D TL N +T L V+ D
Sbjct: 729 ALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD 788
Query: 877 KV 878
V
Sbjct: 789 DV 790
Score = 64.1 bits (149), Expect = 2e-09
Identities = 36/112 (32%), Positives = 61/112 (54%), Gaps = 3/112 (2%)
Query: 770 TALHYAARYGLD---EFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
TALH AA + C +L+ AN+N + K+ TPLH+A+ V+ +++ + A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+NA+D T LH A+ G++ ++LLSY D +++ TAL + + V
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENV 477
Score = 60.5 bits (140), Expect = 3e-08
Identities = 86/383 (22%), Positives = 155/383 (40%), Gaps = 52/383 (13%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEIN--------ATDLNECSA---------- 528
+RD+ T LH A+I GK + LL+ G+E A DL + SA
Sbjct: 119 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKK 178
Query: 529 ---LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
L A S + ++ +L N + + K+TPLHLA + V+ ++ +H
Sbjct: 179 DELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLL---QHGA 235
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQV 645
+++ ++ PLH A +G+ + LL++HG+ + + + T A + ++V
Sbjct: 236 ---DVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEV 292
Query: 646 LKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERI 705
C+ L Y ++ ++C ++ L + T + + +
Sbjct: 293 ---CS-LLLSY----GADPTLLNCHNKSAIDL---------APTPQLKERLAYEFKGHSL 335
Query: 706 LRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESC-----TDFD 760
L+A DV +++++ F P + + H Y KRK + C +
Sbjct: 336 LQAAREADVTRIKKHLSLEMVNFKHP--QTHETALHCAAASPYPKRK-QICELLLRKGAN 392
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+N T LH A+ ++ +++ + A VN + QT LH AA RLL
Sbjct: 393 INEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLL 452
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L G + N I + T L +E
Sbjct: 453 LSYGCDPNIISLQGFTALQMGNE 475
Score = 60.1 bits (139), Expect = 3e-08
Identities = 36/117 (30%), Positives = 63/117 (53%), Gaps = 3/117 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCR--NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDV 832
+AR G +E L+ NVNC + + TPLHLAA N+ +++LLL +GA+++A D
Sbjct: 184 SARSGNEEKMMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDK 242
Query: 833 ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
PLH+A G+ ++L+ + + ++ + T L A K + + L+ +Y
Sbjct: 243 GDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSY 299
Score = 58.4 bits (135), Expect = 1e-07
Identities = 44/123 (35%), Positives = 62/123 (50%), Gaps = 10/123 (8%)
Query: 485 MTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
+ SRD+ G T LH A+ G+ +VE LL+ G+ + A D LH A S GH V+
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 108
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPL 601
+LL GA+ N ++ TPLH A G + C+ + + AE + R N G T L
Sbjct: 109 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIR-------NTDGRTAL 161
Query: 602 HLA 604
LA
Sbjct: 162 DLA 164
Score = 56.8 bits (131), Expect = 3e-07
Identities = 77/365 (21%), Positives = 150/365 (41%), Gaps = 24/365 (6%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
L + +A+D + + LH A+ ++ +LL GA+++ K+ PLH A + GH
Sbjct: 197 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGH 256
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH 630
+ ++ +H +N + TPLH A+ + LL+ +G++P+L N ++
Sbjct: 257 YEVTELLV---KHGA---CVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHN 310
Query: 631 KTAFDYAHNLRILQVL--KSCTPNLFEYIHITS-SEVKK-ISCESEKPTSLKLQNLTLKC 686
K+A D A ++ + L + +L + + +KK +S E + L C
Sbjct: 311 KSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHC 370
Query: 687 SDTNDASKTIENLKLIERILRAIS------YGDVKLACFYMNIDYSAFIAPDKEKSNSLC 740
+ + K + +L+ R I+ + +A + D + + K N+L
Sbjct: 371 AAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALD 430
Query: 741 H----PLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC 796
+ L YC ++C CD N + + A +E N+ + ++
Sbjct: 431 NLGQTSLHRAAYCGH-LQTCRLLLSYGCDPNIISLQGFTALQMGNE--NVQQLLQEGISL 487
Query: 797 RNKKAQTP-LHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLS 855
N +A L A + V +L N I+ ++TPLH A+ + + LL
Sbjct: 488 GNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQ 547
Query: 856 YNPDI 860
+ D+
Sbjct: 548 HGADV 552
Score = 56.8 bits (131), Expect = 3e-07
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 488 RDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
RD+ G T LH+A+ + + E LL+ G+++NA D LH A+S GH +V +L+
Sbjct: 673 RDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLI 732
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPLHLA 604
A +N + TPLH A G C + + A+ + N+ G TPL L
Sbjct: 733 KYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPT-------LKNQEGQTPLDLV 785
Query: 605 S 605
S
Sbjct: 786 S 786
Score = 54.8 bits (126), Expect = 1e-06
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ + V LL GA++N ++ PLH A + GH+ +I +
Sbjct: 683 LHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKY------NA 736
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
+N ++ TPLH A++ G + LL+ HG++P+L+N +T D + +L +
Sbjct: 737 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTA 796
Query: 649 CTP 651
P
Sbjct: 797 AMP 799
Score = 52.8 bits (121), Expect = 5e-06
Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 793 NVNCRNKKAQ--TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAA 850
+VNCR+ + + TPLH AA N+ V+ LL +GA+++A D PLH+A G+ A
Sbjct: 516 SVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVA 575
Query: 851 KILLSYNPDITLLNATEKTAL--AVAKDKVHL 880
++L+ + + + + + T L A AK K +
Sbjct: 576 ELLVKHGAVVNVADLWKFTPLHEAAAKGKYEI 607
Score = 49.6 bits (113), Expect = 5e-05
Identities = 26/80 (32%), Positives = 43/80 (53%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D GL LH A+ +G + L++ + +NATD + LH A+ +G + +L
Sbjct: 705 VNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALL 764
Query: 545 LHSGANINQKNIDKNTPLHL 564
L GA+ KN + TPL L
Sbjct: 765 LAHGADPTLKNQEGQTPLDL 784
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V D G LH A +G E N+L+ + A+ N R+ TPLH AAI K V +
Sbjct: 83 NVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIV 142
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL-SYNPDITLLNA 865
LL +GA RNT A + + A +L Y D L +A
Sbjct: 143 LLQHGAE----PTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185
Score = 44.0 bits (99), Expect = 0.002
Identities = 38/151 (25%), Positives = 72/151 (47%), Gaps = 21/151 (13%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
LT LHVAS +VE +++ +++NA D ++LH A+ GH +LL G + N
Sbjct: 401 LTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 460
Query: 553 QKNIDKNTPLHLAVNN-----------GHLHCVKAIIYFAE----HSGRKI----NINCA 593
++ T L + N G+ + ++ A+ + +K+ ++NC
Sbjct: 461 IISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCR 520
Query: 594 NESG--NTPLHLASKWGYEGIARLLIEHGSE 622
+ G +TPLH A+ + + L++HG++
Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGAD 551
Score = 39.5 bits (88), Expect = 0.052
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 802 QTPLHLAAIN---NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
+T LH AA + + + LLL GANIN TPLH ASE + ++++ +
Sbjct: 365 ETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEA 424
Query: 859 DITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
+ L+ +T+L A HL L+ +Y
Sbjct: 425 KVNALDNLGQTSLHRAAYCGHLQTCRLLLSY 455
>AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein.
Length = 1166
Score = 74.9 bits (176), Expect = 1e-12
Identities = 44/120 (36%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
Query: 757 TDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
T +VN S+G T LH AA Y + +L+ + A+V+ ++K PLH A
Sbjct: 198 TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY 257
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V LL+ +GA +NA+D+ + TPLH+A+ + +LLSY D TLLN K+A+ +A
Sbjct: 258 EVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLA 317
Score = 72.1 bits (169), Expect = 8e-12
Identities = 80/320 (25%), Positives = 147/320 (45%), Gaps = 32/320 (10%)
Query: 504 KATIVETLLEMGS--EINATDLN--ECSALHYASSRGHQNVLLMLLHSGANINQKNIDKN 559
KA VET+ ++ + +N D+ + + LH+A+ +V+ LL GA+++ K+
Sbjct: 501 KAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGL 560
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
PLH A + GH + ++ +H G +N+ A+ TPLH A+ G I +LL++H
Sbjct: 561 VPLHNACSYGHYEVAELLV---KH-GAVVNV--ADLWKFTPLHEAAAKGKYEICKLLLQH 614
Query: 620 GSEPSLQNSYHKTAFDYAH--NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G++P+ +N T D + I +L+ L + VKK+S P ++
Sbjct: 615 GADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLS----SPDNV 670
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ + S + NL++ E +L+ DV N + P N
Sbjct: 671 NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQ--HGADV-------NAQDKGGLIP---LHN 718
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCR 797
+ + + K +C VN D FT LH AA+ G + C +L+ + A+ +
Sbjct: 719 AASYGHVDVAALLIKYNAC----VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLK 774
Query: 798 NKKAQTPLHLAAINNKTVVI 817
N++ QTPL L + ++ + ++
Sbjct: 775 NQEGQTPLDLVSADDVSALL 794
Score = 70.5 bits (165), Expect = 2e-11
Identities = 44/116 (37%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Query: 761 VNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
VN D+ G T LH+AA +G + L+ N ANV R+ PLH A V+
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 108
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LLL +GA+ NA D TPLH+A+ G I +LL + + T+ N +TAL +A
Sbjct: 109 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 68.9 bits (161), Expect = 7e-11
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 2/123 (1%)
Query: 756 CTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
CT VN D G T LH+AA Y L+ + A+V+ ++K PLH A
Sbjct: 512 CTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGH 571
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
V LL+ +GA +N D+ + TPLH+A+ G K+LL + D T N T L +
Sbjct: 572 YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 631
Query: 874 AKD 876
KD
Sbjct: 632 VKD 634
Score = 65.7 bits (153), Expect = 7e-10
Identities = 42/125 (33%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 481 TCPTMTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQ 538
T ++ RD G T LH A+ + + ++VE LL+ G++++A D LH A S GH
Sbjct: 513 TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHY 572
Query: 539 NVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGN 598
V +L+ GA +N ++ K TPLH A G K ++ +K N GN
Sbjct: 573 EVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKK------NRDGN 626
Query: 599 TPLHL 603
TPL L
Sbjct: 627 TPLDL 631
Score = 64.5 bits (150), Expect = 2e-09
Identities = 79/293 (26%), Positives = 129/293 (44%), Gaps = 35/293 (11%)
Query: 517 EINATDL--NECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCV 574
++N+ D + + LH+A+ G ++V+ LL +GAN+ ++ PLH A + GH V
Sbjct: 48 KVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVV 107
Query: 575 KAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAF 634
++ + N N TPLH A+ G + +L++HG+EP+++N+ +TA
Sbjct: 108 NLLLRHGADPNARDNWNY------TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTAL 161
Query: 635 DYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASK 694
D A K+ ++ + S S EK +L L L + C ++
Sbjct: 162 DLAD-----PSAKAVLTGEYKKDELLES---ARSGNEEKMMAL-LTPLNVNCHASDGRKS 212
Query: 695 TIENLKLIERILRAISYGDVKLACFYMNIDYSAFI-APDKEKSNSLCHPLCECQYCKRKT 753
T +L A Y VK+ + + + A + A DK L H C + + T
Sbjct: 213 TPLHL--------AAGYNRVKIV--QLLLQHGADVHAKDKGDLVPL-HNACSYGHYE-VT 260
Query: 754 ESCTDFD--VNVCDSNGFTALHYAARYGLDEFCNILIFNRAN---VNCRNKKA 801
E VN D FT LH AA E C++L+ A+ +NC NK A
Sbjct: 261 ELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 313
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/122 (36%), Positives = 62/122 (50%), Gaps = 3/122 (2%)
Query: 760 DVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+VN D+ G T LH AA Y E L+ + A+VN ++K PLH AA V
Sbjct: 669 NVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVA 728
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL-AVAKD 876
LL+ A +NA D TPLH+A++ G +LL++ D TL N +T L V+ D
Sbjct: 729 ALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD 788
Query: 877 KV 878
V
Sbjct: 789 DV 790
Score = 64.1 bits (149), Expect = 2e-09
Identities = 36/112 (32%), Positives = 61/112 (54%), Gaps = 3/112 (2%)
Query: 770 TALHYAARYGLD---EFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
TALH AA + C +L+ AN+N + K+ TPLH+A+ V+ +++ + A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+NA+D T LH A+ G++ ++LLSY D +++ TAL + + V
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENV 477
Score = 60.5 bits (140), Expect = 3e-08
Identities = 86/383 (22%), Positives = 155/383 (40%), Gaps = 52/383 (13%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEIN--------ATDLNECSA---------- 528
+RD+ T LH A+I GK + LL+ G+E A DL + SA
Sbjct: 119 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKK 178
Query: 529 ---LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
L A S + ++ +L N + + K+TPLHLA + V+ ++ +H
Sbjct: 179 DELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLL---QHGA 235
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQV 645
+++ ++ PLH A +G+ + LL++HG+ + + + T A + ++V
Sbjct: 236 ---DVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEV 292
Query: 646 LKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERI 705
C+ L Y ++ ++C ++ L + T + + +
Sbjct: 293 ---CS-LLLSY----GADPTLLNCHNKSAIDL---------APTPQLKERLAYEFKGHSL 335
Query: 706 LRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESC-----TDFD 760
L+A DV +++++ F P + + H Y KRK + C +
Sbjct: 336 LQAAREADVTRIKKHLSLEMVNFKHP--QTHETALHCAAASPYPKRK-QICELLLRKGAN 392
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+N T LH A+ ++ +++ + A VN + QT LH AA RLL
Sbjct: 393 INEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLL 452
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L G + N I + T L +E
Sbjct: 453 LSYGCDPNIISLQGFTALQMGNE 475
Score = 60.1 bits (139), Expect = 3e-08
Identities = 36/117 (30%), Positives = 63/117 (53%), Gaps = 3/117 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCR--NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDV 832
+AR G +E L+ NVNC + + TPLHLAA N+ +++LLL +GA+++A D
Sbjct: 184 SARSGNEEKMMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDK 242
Query: 833 ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
PLH+A G+ ++L+ + + ++ + T L A K + + L+ +Y
Sbjct: 243 GDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSY 299
Score = 58.4 bits (135), Expect = 1e-07
Identities = 44/123 (35%), Positives = 62/123 (50%), Gaps = 10/123 (8%)
Query: 485 MTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
+ SRD+ G T LH A+ G+ +VE LL+ G+ + A D LH A S GH V+
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 108
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPL 601
+LL GA+ N ++ TPLH A G + C+ + + AE + R N G T L
Sbjct: 109 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIR-------NTDGRTAL 161
Query: 602 HLA 604
LA
Sbjct: 162 DLA 164
Score = 56.8 bits (131), Expect = 3e-07
Identities = 77/365 (21%), Positives = 150/365 (41%), Gaps = 24/365 (6%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
L + +A+D + + LH A+ ++ +LL GA+++ K+ PLH A + GH
Sbjct: 197 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGH 256
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH 630
+ ++ +H +N + TPLH A+ + LL+ +G++P+L N ++
Sbjct: 257 YEVTELLV---KHGA---CVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHN 310
Query: 631 KTAFDYAHNLRILQVL--KSCTPNLFEYIHITS-SEVKK-ISCESEKPTSLKLQNLTLKC 686
K+A D A ++ + L + +L + + +KK +S E + L C
Sbjct: 311 KSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHC 370
Query: 687 SDTNDASKTIENLKLIERILRAIS------YGDVKLACFYMNIDYSAFIAPDKEKSNSLC 740
+ + K + +L+ R I+ + +A + D + + K N+L
Sbjct: 371 AAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALD 430
Query: 741 H----PLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC 796
+ L YC ++C CD N + + A +E N+ + ++
Sbjct: 431 NLGQTSLHRAAYCGH-LQTCRLLLSYGCDPNIISLQGFTALQMGNE--NVQQLLQEGISL 487
Query: 797 RNKKAQTP-LHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLS 855
N +A L A + V +L N I+ ++TPLH A+ + + LL
Sbjct: 488 GNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQ 547
Query: 856 YNPDI 860
+ D+
Sbjct: 548 HGADV 552
Score = 56.8 bits (131), Expect = 3e-07
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 488 RDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
RD+ G T LH+A+ + + E LL+ G+++NA D LH A+S GH +V +L+
Sbjct: 673 RDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLI 732
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPLHLA 604
A +N + TPLH A G C + + A+ + N+ G TPL L
Sbjct: 733 KYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPT-------LKNQEGQTPLDLV 785
Query: 605 S 605
S
Sbjct: 786 S 786
Score = 54.8 bits (126), Expect = 1e-06
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ + V LL GA++N ++ PLH A + GH+ +I +
Sbjct: 683 LHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKY------NA 736
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
+N ++ TPLH A++ G + LL+ HG++P+L+N +T D + +L +
Sbjct: 737 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTA 796
Query: 649 CTP 651
P
Sbjct: 797 AMP 799
Score = 52.8 bits (121), Expect = 5e-06
Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 793 NVNCRNKKAQ--TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAA 850
+VNCR+ + + TPLH AA N+ V+ LL +GA+++A D PLH+A G+ A
Sbjct: 516 SVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVA 575
Query: 851 KILLSYNPDITLLNATEKTAL--AVAKDKVHL 880
++L+ + + + + + T L A AK K +
Sbjct: 576 ELLVKHGAVVNVADLWKFTPLHEAAAKGKYEI 607
Score = 49.6 bits (113), Expect = 5e-05
Identities = 26/80 (32%), Positives = 43/80 (53%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D GL LH A+ +G + L++ + +NATD + LH A+ +G + +L
Sbjct: 705 VNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALL 764
Query: 545 LHSGANINQKNIDKNTPLHL 564
L GA+ KN + TPL L
Sbjct: 765 LAHGADPTLKNQEGQTPLDL 784
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V D G LH A +G E N+L+ + A+ N R+ TPLH AAI K V +
Sbjct: 83 NVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIV 142
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL-SYNPDITLLNA 865
LL +GA RNT A + + A +L Y D L +A
Sbjct: 143 LLQHGAE----PTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185
Score = 44.0 bits (99), Expect = 0.002
Identities = 38/151 (25%), Positives = 72/151 (47%), Gaps = 21/151 (13%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
LT LHVAS +VE +++ +++NA D ++LH A+ GH +LL G + N
Sbjct: 401 LTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 460
Query: 553 QKNIDKNTPLHLAVNN-----------GHLHCVKAIIYFAE----HSGRKI----NINCA 593
++ T L + N G+ + ++ A+ + +K+ ++NC
Sbjct: 461 IISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCR 520
Query: 594 NESG--NTPLHLASKWGYEGIARLLIEHGSE 622
+ G +TPLH A+ + + L++HG++
Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGAD 551
Score = 39.5 bits (88), Expect = 0.052
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 802 QTPLHLAAIN---NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
+T LH AA + + + LLL GANIN TPLH ASE + ++++ +
Sbjct: 365 ETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEA 424
Query: 859 DITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
+ L+ +T+L A HL L+ +Y
Sbjct: 425 KVNALDNLGQTSLHRAAYCGHLQTCRLLLSY 455
>AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related protein
protein.
Length = 1265
Score = 74.9 bits (176), Expect = 1e-12
Identities = 44/120 (36%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
Query: 757 TDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
T +VN S+G T LH AA Y + +L+ + A+V+ ++K PLH A
Sbjct: 298 TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY 357
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V LL+ +GA +NA+D+ + TPLH+A+ + +LLSY D TLLN K+A+ +A
Sbjct: 358 EVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLA 417
Score = 74.9 bits (176), Expect = 1e-12
Identities = 101/408 (24%), Positives = 173/408 (42%), Gaps = 43/408 (10%)
Query: 506 TIVETLLEMGSEINATDLNECSALHYASSRGH---QNVLLMLLHSGANINQKNIDKNTPL 562
T ++ L + I A+ +E +ALH A++ + + + +LL GANIN+K + TPL
Sbjct: 445 TRIKKHLSLEMVIQASQTHE-TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPL 503
Query: 563 HLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSE 622
H+A H V+ ++ +H + +N + G T LH A+ G+ RLL+ +G +
Sbjct: 504 HVASEKAHNDVVEVVV---KHEAK---VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCD 557
Query: 623 PSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNL 682
P++ + TA N + Q+L+ E I + +SE + E+ K ++ +
Sbjct: 558 PNIISLQGFTALQMG-NENVQQLLQ-------EGISLGNSEADRQLLEAAKAGD--VETV 607
Query: 683 TLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHP 742
C+ + + IE + + A Y V + + + A DK L +
Sbjct: 608 KKLCTVQSVNCRDIEG-RQSTPLHFAAGYNRVSVVEYLLQHGADVH-AKDKGGLVPLHNA 665
Query: 743 LCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQ 802
Y + VNV D FT LH AA G E C +L+ + A+ +N+
Sbjct: 666 CSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGN 725
Query: 803 TPLHLAAINNKTV--VIR---LLLD--------------NGANINAIDV--ARNTPLHDA 841
TPL L + + ++R LLD + N+N D +TPLH A
Sbjct: 726 TPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLA 785
Query: 842 SETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
+ N+ A+ LL + D+ + L A H+ + L+ Y
Sbjct: 786 AGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKY 833
Score = 72.1 bits (169), Expect = 8e-12
Identities = 80/320 (25%), Positives = 147/320 (45%), Gaps = 32/320 (10%)
Query: 504 KATIVETLLEMGS--EINATDLN--ECSALHYASSRGHQNVLLMLLHSGANINQKNIDKN 559
KA VET+ ++ + +N D+ + + LH+A+ +V+ LL GA+++ K+
Sbjct: 600 KAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGL 659
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
PLH A + GH + ++ +H G +N+ A+ TPLH A+ G I +LL++H
Sbjct: 660 VPLHNACSYGHYEVAELLV---KH-GAVVNV--ADLWKFTPLHEAAAKGKYEICKLLLQH 713
Query: 620 GSEPSLQNSYHKTAFDYAH--NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G++P+ +N T D + I +L+ L + VKK+S P ++
Sbjct: 714 GADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLS----SPDNV 769
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ + S + NL++ E +L+ DV N + P N
Sbjct: 770 NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQ--HGADV-------NAQDKGGLIP---LHN 817
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCR 797
+ + + K +C VN D FT LH AA+ G + C +L+ + A+ +
Sbjct: 818 AASYGHVDVAALLIKYNAC----VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLK 873
Query: 798 NKKAQTPLHLAAINNKTVVI 817
N++ QTPL L + ++ + ++
Sbjct: 874 NQEGQTPLDLVSADDVSALL 893
Score = 70.9 bits (166), Expect = 2e-11
Identities = 44/116 (37%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Query: 761 VNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
VN D+ G T LH+AA +G + L+ N ANV R+ PLH A V+
Sbjct: 149 VNSRDTAGRKSTPLHFAAXFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 208
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LLL +GA+ NA D TPLH+A+ G I +LL + + T+ N +TAL +A
Sbjct: 209 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 264
Score = 65.7 bits (153), Expect = 7e-10
Identities = 42/125 (33%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 481 TCPTMTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQ 538
T ++ RD G T LH A+ + + ++VE LL+ G++++A D LH A S GH
Sbjct: 612 TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHY 671
Query: 539 NVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGN 598
V +L+ GA +N ++ K TPLH A G K ++ +K N GN
Sbjct: 672 EVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKK------NRDGN 725
Query: 599 TPLHL 603
TPL L
Sbjct: 726 TPLDL 730
Score = 64.5 bits (150), Expect = 2e-09
Identities = 79/293 (26%), Positives = 129/293 (44%), Gaps = 35/293 (11%)
Query: 517 EINATDL--NECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCV 574
++N+ D + + LH+A+ G ++V+ LL +GAN+ ++ PLH A + GH V
Sbjct: 148 KVNSRDTAGRKSTPLHFAAXFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVV 207
Query: 575 KAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAF 634
++ + N N TPLH A+ G + +L++HG+EP+++N+ +TA
Sbjct: 208 NLLLRHGADPNARDNWNY------TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTAL 261
Query: 635 DYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASK 694
D A K+ ++ + S S EK +L L L + C ++
Sbjct: 262 DLAD-----PSAKAVLTGEYKKDELLES---ARSGNEEKMMAL-LTPLNVNCHASDGRKS 312
Query: 695 TIENLKLIERILRAISYGDVKLACFYMNIDYSAFI-APDKEKSNSLCHPLCECQYCKRKT 753
T +L A Y VK+ + + + A + A DK L H C + + T
Sbjct: 313 TPLHL--------AAGYNRVKIV--QLLLQHGADVHAKDKGDLVPL-HNACSYGHYE-VT 360
Query: 754 ESCTDFD--VNVCDSNGFTALHYAARYGLDEFCNILIFNRAN---VNCRNKKA 801
E VN D FT LH AA E C++L+ A+ +NC NK A
Sbjct: 361 ELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 413
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/122 (36%), Positives = 62/122 (50%), Gaps = 3/122 (2%)
Query: 760 DVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+VN D+ G T LH AA Y E L+ + A+VN ++K PLH AA V
Sbjct: 768 NVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVA 827
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL-AVAKD 876
LL+ A +NA D TPLH+A++ G +LL++ D TL N +T L V+ D
Sbjct: 828 ALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD 887
Query: 877 KV 878
V
Sbjct: 888 DV 889
Score = 60.1 bits (139), Expect = 3e-08
Identities = 36/117 (30%), Positives = 63/117 (53%), Gaps = 3/117 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCR--NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDV 832
+AR G +E L+ NVNC + + TPLHLAA N+ +++LLL +GA+++A D
Sbjct: 284 SARSGNEEKMMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDK 342
Query: 833 ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
PLH+A G+ ++L+ + + ++ + T L A K + + L+ +Y
Sbjct: 343 GDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSY 399
Score = 59.7 bits (138), Expect = 5e-08
Identities = 44/123 (35%), Positives = 62/123 (50%), Gaps = 10/123 (8%)
Query: 485 MTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
+ SRD+ G T LH A+ G+ +VE LL+ G+ + A D LH A S GH V+
Sbjct: 149 VNSRDTAGRKSTPLHFAAXFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 208
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPL 601
+LL GA+ N ++ TPLH A G + C+ + + AE + R N G T L
Sbjct: 209 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIR-------NTDGRTAL 261
Query: 602 HLA 604
LA
Sbjct: 262 DLA 264
Score = 59.3 bits (137), Expect = 6e-08
Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 5/109 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D T LH+A+ + + IV+ LL+ G++++A D + LH A S GH V +L+ G
Sbjct: 308 DGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHG 367
Query: 549 ANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANES 596
A +N ++ + TPLH A + + C + Y A+ + +NC N+S
Sbjct: 368 ACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPT----LLNCHNKS 412
Score = 58.0 bits (134), Expect = 1e-07
Identities = 85/383 (22%), Positives = 155/383 (40%), Gaps = 53/383 (13%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEIN--------ATDLNECSA---------- 528
+RD+ T LH A+I GK + LL+ G+E A DL + SA
Sbjct: 219 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKK 278
Query: 529 ---LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
L A S + ++ +L N + + K+TPLHLA + V+ ++ +H
Sbjct: 279 DELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLL---QHGA 335
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA---HNLRI 642
+++ ++ PLH A +G+ + LL++HG+ + + + T A + + +
Sbjct: 336 ---DVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEV 392
Query: 643 LQVLKS--CTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLK 700
+L S P L + ++ ++ E+ + L + D ++ ++L
Sbjct: 393 CSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYEFQRPLVAAXAREADVTRIKKHLS 452
Query: 701 LIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTDFD 760
L E +++A + L C A +P ++ C+ RK +
Sbjct: 453 L-EMVIQASQTHETALHC--------AAASPYPKRKQI-------CELLLRK-----GAN 491
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+N T LH A+ ++ +++ + A VN + QT LH AA RLL
Sbjct: 492 INEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLL 551
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L G + N I + T L +E
Sbjct: 552 LSYGCDPNIISLQGFTALQMGNE 574
Score = 56.8 bits (131), Expect = 3e-07
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 488 RDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
RD+ G T LH+A+ + + E LL+ G+++NA D LH A+S GH +V +L+
Sbjct: 772 RDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLI 831
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPLHLA 604
A +N + TPLH A G C + + A+ + N+ G TPL L
Sbjct: 832 KYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPT-------LKNQEGQTPLDLV 884
Query: 605 S 605
S
Sbjct: 885 S 885
Score = 54.8 bits (126), Expect = 1e-06
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ + V LL GA++N ++ PLH A + GH+ +I +
Sbjct: 782 LHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKY------NA 835
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
+N ++ TPLH A++ G + LL+ HG++P+L+N +T D + +L +
Sbjct: 836 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTA 895
Query: 649 CTP 651
P
Sbjct: 896 AMP 898
Score = 49.6 bits (113), Expect = 5e-05
Identities = 26/80 (32%), Positives = 43/80 (53%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D GL LH A+ +G + L++ + +NATD + LH A+ +G + +L
Sbjct: 804 VNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALL 863
Query: 545 LHSGANINQKNIDKNTPLHL 564
L GA+ KN + TPL L
Sbjct: 864 LAHGADPTLKNQEGQTPLDL 883
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V D G LH A +G E N+L+ + A+ N R+ TPLH AAI K V +
Sbjct: 183 NVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIV 242
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL-SYNPDITLLNA 865
LL +GA RNT A + + A +L Y D L +A
Sbjct: 243 LLQHGAE----PTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 285
Score = 44.0 bits (99), Expect = 0.002
Identities = 38/151 (25%), Positives = 72/151 (47%), Gaps = 21/151 (13%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
LT LHVAS +VE +++ +++NA D ++LH A+ GH +LL G + N
Sbjct: 500 LTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 559
Query: 553 QKNIDKNTPLHLAVNN-----------GHLHCVKAIIYFAE----HSGRKI----NINCA 593
++ T L + N G+ + ++ A+ + +K+ ++NC
Sbjct: 560 IISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCR 619
Query: 594 NESG--NTPLHLASKWGYEGIARLLIEHGSE 622
+ G +TPLH A+ + + L++HG++
Sbjct: 620 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGAD 650
>AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein
protein.
Length = 1166
Score = 74.9 bits (176), Expect = 1e-12
Identities = 44/120 (36%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
Query: 757 TDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
T +VN S+G T LH AA Y + +L+ + A+V+ ++K PLH A
Sbjct: 198 TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY 257
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
V LL+ +GA +NA+D+ + TPLH+A+ + +LLSY D TLLN K+A+ +A
Sbjct: 258 EVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLA 317
Score = 72.1 bits (169), Expect = 8e-12
Identities = 80/320 (25%), Positives = 147/320 (45%), Gaps = 32/320 (10%)
Query: 504 KATIVETLLEMGS--EINATDLN--ECSALHYASSRGHQNVLLMLLHSGANINQKNIDKN 559
KA VET+ ++ + +N D+ + + LH+A+ +V+ LL GA+++ K+
Sbjct: 501 KAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGL 560
Query: 560 TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEH 619
PLH A + GH + ++ +H G +N+ A+ TPLH A+ G I +LL++H
Sbjct: 561 VPLHNACSYGHYEVAELLV---KH-GAVVNV--ADLWKFTPLHEAAAKGKYEICKLLLQH 614
Query: 620 GSEPSLQNSYHKTAFDYAH--NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSL 677
G++P+ +N T D + I +L+ L + VKK+S P ++
Sbjct: 615 GADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLS----SPDNV 670
Query: 678 KLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSN 737
++ + S + NL++ E +L+ DV N + P N
Sbjct: 671 NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQ--HGADV-------NAQDKGGLIP---LHN 718
Query: 738 SLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCR 797
+ + + K +C VN D FT LH AA+ G + C +L+ + A+ +
Sbjct: 719 AASYGHVDVAALLIKYNAC----VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLK 774
Query: 798 NKKAQTPLHLAAINNKTVVI 817
N++ QTPL L + ++ + ++
Sbjct: 775 NQEGQTPLDLVSADDVSALL 794
Score = 70.5 bits (165), Expect = 2e-11
Identities = 44/116 (37%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Query: 761 VNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
VN D+ G T LH+AA +G + L+ N ANV R+ PLH A V+
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 108
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
LLL +GA+ NA D TPLH+A+ G I +LL + + T+ N +TAL +A
Sbjct: 109 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 68.9 bits (161), Expect = 7e-11
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 2/123 (1%)
Query: 756 CTDFDVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNK 813
CT VN D G T LH+AA Y L+ + A+V+ ++K PLH A
Sbjct: 512 CTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGH 571
Query: 814 TVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV 873
V LL+ +GA +N D+ + TPLH+A+ G K+LL + D T N T L +
Sbjct: 572 YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 631
Query: 874 AKD 876
KD
Sbjct: 632 VKD 634
Score = 65.7 bits (153), Expect = 7e-10
Identities = 42/125 (33%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 481 TCPTMTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQ 538
T ++ RD G T LH A+ + + ++VE LL+ G++++A D LH A S GH
Sbjct: 513 TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHY 572
Query: 539 NVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGN 598
V +L+ GA +N ++ K TPLH A G K ++ +K N GN
Sbjct: 573 EVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKK------NRDGN 626
Query: 599 TPLHL 603
TPL L
Sbjct: 627 TPLDL 631
Score = 64.5 bits (150), Expect = 2e-09
Identities = 79/293 (26%), Positives = 129/293 (44%), Gaps = 35/293 (11%)
Query: 517 EINATDL--NECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCV 574
++N+ D + + LH+A+ G ++V+ LL +GAN+ ++ PLH A + GH V
Sbjct: 48 KVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVV 107
Query: 575 KAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAF 634
++ + N N TPLH A+ G + +L++HG+EP+++N+ +TA
Sbjct: 108 NLLLRHGADPNARDNWNY------TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTAL 161
Query: 635 DYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASK 694
D A K+ ++ + S S EK +L L L + C ++
Sbjct: 162 DLAD-----PSAKAVLTGEYKKDELLES---ARSGNEEKMMAL-LTPLNVNCHASDGRKS 212
Query: 695 TIENLKLIERILRAISYGDVKLACFYMNIDYSAFI-APDKEKSNSLCHPLCECQYCKRKT 753
T +L A Y VK+ + + + A + A DK L H C + + T
Sbjct: 213 TPLHL--------AAGYNRVKIV--QLLLQHGADVHAKDKGDLVPL-HNACSYGHYE-VT 260
Query: 754 ESCTDFD--VNVCDSNGFTALHYAARYGLDEFCNILIFNRAN---VNCRNKKA 801
E VN D FT LH AA E C++L+ A+ +NC NK A
Sbjct: 261 ELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 313
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/122 (36%), Positives = 62/122 (50%), Gaps = 3/122 (2%)
Query: 760 DVNVCDSNG--FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVI 817
+VN D+ G T LH AA Y E L+ + A+VN ++K PLH AA V
Sbjct: 669 NVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVA 728
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTAL-AVAKD 876
LL+ A +NA D TPLH+A++ G +LL++ D TL N +T L V+ D
Sbjct: 729 ALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD 788
Query: 877 KV 878
V
Sbjct: 789 DV 790
Score = 64.1 bits (149), Expect = 2e-09
Identities = 36/112 (32%), Positives = 61/112 (54%), Gaps = 3/112 (2%)
Query: 770 TALHYAARYGLD---EFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGAN 826
TALH AA + C +L+ AN+N + K+ TPLH+A+ V+ +++ + A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 827 INAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
+NA+D T LH A+ G++ ++LLSY D +++ TAL + + V
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENV 477
Score = 60.5 bits (140), Expect = 3e-08
Identities = 86/383 (22%), Positives = 155/383 (40%), Gaps = 52/383 (13%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEIN--------ATDLNECSA---------- 528
+RD+ T LH A+I GK + LL+ G+E A DL + SA
Sbjct: 119 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKK 178
Query: 529 ---LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
L A S + ++ +L N + + K+TPLHLA + V+ ++ +H
Sbjct: 179 DELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLL---QHGA 235
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQV 645
+++ ++ PLH A +G+ + LL++HG+ + + + T A + ++V
Sbjct: 236 ---DVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEV 292
Query: 646 LKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERI 705
C+ L Y ++ ++C ++ L + T + + +
Sbjct: 293 ---CS-LLLSY----GADPTLLNCHNKSAIDL---------APTPQLKERLAYEFKGHSL 335
Query: 706 LRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESC-----TDFD 760
L+A DV +++++ F P + + H Y KRK + C +
Sbjct: 336 LQAAREADVTRIKKHLSLEMVNFKHP--QTHETALHCAAASPYPKRK-QICELLLRKGAN 392
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+N T LH A+ ++ +++ + A VN + QT LH AA RLL
Sbjct: 393 INEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLL 452
Query: 821 LDNGANINAIDVARNTPLHDASE 843
L G + N I + T L +E
Sbjct: 453 LSYGCDPNIISLQGFTALQMGNE 475
Score = 60.1 bits (139), Expect = 3e-08
Identities = 36/117 (30%), Positives = 63/117 (53%), Gaps = 3/117 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCR--NKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDV 832
+AR G +E L+ NVNC + + TPLHLAA N+ +++LLL +GA+++A D
Sbjct: 184 SARSGNEEKMMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDK 242
Query: 833 ARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
PLH+A G+ ++L+ + + ++ + T L A K + + L+ +Y
Sbjct: 243 GDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSY 299
Score = 58.4 bits (135), Expect = 1e-07
Identities = 44/123 (35%), Positives = 62/123 (50%), Gaps = 10/123 (8%)
Query: 485 MTSRDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
+ SRD+ G T LH A+ G+ +VE LL+ G+ + A D LH A S GH V+
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVN 108
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPL 601
+LL GA+ N ++ TPLH A G + C+ + + AE + R N G T L
Sbjct: 109 LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIR-------NTDGRTAL 161
Query: 602 HLA 604
LA
Sbjct: 162 DLA 164
Score = 56.8 bits (131), Expect = 3e-07
Identities = 77/365 (21%), Positives = 150/365 (41%), Gaps = 24/365 (6%)
Query: 511 LLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGH 570
L + +A+D + + LH A+ ++ +LL GA+++ K+ PLH A + GH
Sbjct: 197 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGH 256
Query: 571 LHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYH 630
+ ++ +H +N + TPLH A+ + LL+ +G++P+L N ++
Sbjct: 257 YEVTELLV---KHGA---CVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHN 310
Query: 631 KTAFDYAHNLRILQVL--KSCTPNLFEYIHITS-SEVKK-ISCESEKPTSLKLQNLTLKC 686
K+A D A ++ + L + +L + + +KK +S E + L C
Sbjct: 311 KSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHC 370
Query: 687 SDTNDASKTIENLKLIERILRAIS------YGDVKLACFYMNIDYSAFIAPDKEKSNSLC 740
+ + K + +L+ R I+ + +A + D + + K N+L
Sbjct: 371 AAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALD 430
Query: 741 H----PLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNC 796
+ L YC ++C CD N + + A +E N+ + ++
Sbjct: 431 NLGQTSLHRAAYCGH-LQTCRLLLSYGCDPNIISLQGFTALQMGNE--NVQQLLQEGISL 487
Query: 797 RNKKAQTP-LHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLS 855
N +A L A + V +L N I+ ++TPLH A+ + + LL
Sbjct: 488 GNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQ 547
Query: 856 YNPDI 860
+ D+
Sbjct: 548 HGADV 552
Score = 56.8 bits (131), Expect = 3e-07
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 488 RDSHGL--TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
RD+ G T LH+A+ + + E LL+ G+++NA D LH A+S GH +V +L+
Sbjct: 673 RDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLI 732
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLH-CVKAIIYFAEHSGRKININCANESGNTPLHLA 604
A +N + TPLH A G C + + A+ + N+ G TPL L
Sbjct: 733 KYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPT-------LKNQEGQTPLDLV 785
Query: 605 S 605
S
Sbjct: 786 S 786
Score = 54.8 bits (126), Expect = 1e-06
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ + V LL GA++N ++ PLH A + GH+ +I +
Sbjct: 683 LHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKY------NA 736
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
+N ++ TPLH A++ G + LL+ HG++P+L+N +T D + +L +
Sbjct: 737 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTA 796
Query: 649 CTP 651
P
Sbjct: 797 AMP 799
Score = 52.8 bits (121), Expect = 5e-06
Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 793 NVNCRNKKAQ--TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAA 850
+VNCR+ + + TPLH AA N+ V+ LL +GA+++A D PLH+A G+ A
Sbjct: 516 SVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVA 575
Query: 851 KILLSYNPDITLLNATEKTAL--AVAKDKVHL 880
++L+ + + + + + T L A AK K +
Sbjct: 576 ELLVKHGAVVNVADLWKFTPLHEAAAKGKYEI 607
Score = 49.6 bits (113), Expect = 5e-05
Identities = 26/80 (32%), Positives = 43/80 (53%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D GL LH A+ +G + L++ + +NATD + LH A+ +G + +L
Sbjct: 705 VNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALL 764
Query: 545 LHSGANINQKNIDKNTPLHL 564
L GA+ KN + TPL L
Sbjct: 765 LAHGADPTLKNQEGQTPLDL 784
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V D G LH A +G E N+L+ + A+ N R+ TPLH AAI K V +
Sbjct: 83 NVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIV 142
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILL-SYNPDITLLNA 865
LL +GA RNT A + + A +L Y D L +A
Sbjct: 143 LLQHGAE----PTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185
Score = 44.0 bits (99), Expect = 0.002
Identities = 38/151 (25%), Positives = 72/151 (47%), Gaps = 21/151 (13%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
LT LHVAS +VE +++ +++NA D ++LH A+ GH +LL G + N
Sbjct: 401 LTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 460
Query: 553 QKNIDKNTPLHLAVNN-----------GHLHCVKAIIYFAE----HSGRKI----NINCA 593
++ T L + N G+ + ++ A+ + +K+ ++NC
Sbjct: 461 IISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCR 520
Query: 594 NESG--NTPLHLASKWGYEGIARLLIEHGSE 622
+ G +TPLH A+ + + L++HG++
Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGAD 551
Score = 39.5 bits (88), Expect = 0.052
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 802 QTPLHLAAIN---NKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNP 858
+T LH AA + + + LLL GANIN TPLH ASE + ++++ +
Sbjct: 365 ETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEA 424
Query: 859 DITLLNATEKTALAVAKDKVHLTIIDLIDNY 889
+ L+ +T+L A HL L+ +Y
Sbjct: 425 KVNALDNLGQTSLHRAAYCGHLQTCRLLLSY 455
>U05681-1|AAC51348.1| 368|Homo sapiens B-cell leukemia/lymphoma 3
protein.
Length = 368
Score = 74.5 bits (175), Expect = 1e-12
Identities = 50/164 (30%), Positives = 85/164 (51%), Gaps = 11/164 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGS----EINATDLNECSALHYASSRGHQNVLLML 544
D HG TA H+A H T + LL+ + ++ A + + +ALH A + Q + +L
Sbjct: 116 DRHGQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVAVNTECQETVQLL 175
Query: 545 LHSGANINQKNIDKN-TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L GA+I+ +I +PL AV N L V+ ++ +H N+N SG++ LH
Sbjct: 176 LERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLL---QHGA---NVNAQMYSGSSALHS 229
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
AS G + R L+ G++ SL+N ++ T A + R++ +L+
Sbjct: 230 ASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVARSRRVIDILR 273
Score = 65.3 bits (152), Expect = 9e-10
Identities = 42/138 (30%), Positives = 72/138 (52%), Gaps = 4/138 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRN-KKAQTPLHLAAINNKTVVIR 818
D+ + +G TALH A E +L+ A+++ + K ++PL A NN +++
Sbjct: 148 DLEARNYDGLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQ 207
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LLL +GAN+NA + ++ LH AS G + + L+ D +L N T L VA+ +
Sbjct: 208 LLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVARSR- 266
Query: 879 HLTIIDLIDNYANKYANT 896
+ID++ A + A+T
Sbjct: 267 --RVIDILRGKATRPAST 282
Score = 57.2 bits (132), Expect = 2e-07
Identities = 41/121 (33%), Positives = 63/121 (52%), Gaps = 7/121 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNE-CSALHYASSRGHQNVLLM 543
+ +R+ GLTALHVA V+ LLE G++I+A D+ S L +A +++ +
Sbjct: 149 LEARNYDGLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQL 208
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GAN+N + ++ LH A G L V+ ++ S K NC N+ TPL +
Sbjct: 209 LLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLK---NCHND---TPLMV 262
Query: 604 A 604
A
Sbjct: 263 A 263
Score = 49.6 bits (113), Expect = 5e-05
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Query: 557 DKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLL 616
D +TPLH+AV G+L V ++ + GR+++I N TPLHLA + RLL
Sbjct: 48 DGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDI--YNNLRQTPLHLAVITTLPSVVRLL 105
Query: 617 IEHGSEPSLQNSYHKTA 633
+ G+ P + + +TA
Sbjct: 106 VTAGASPMALDRHGQTA 122
Score = 46.4 bits (105), Expect = 5e-04
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEM----GSEINATDLNECSALHYASSRGHQNVL 541
T D G T LH+A + G V L+ + G E++ + + LH A +V+
Sbjct: 43 TRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVV 102
Query: 542 LMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L+ +GA+ + T HLA + C++A++ A + +++ N G T L
Sbjct: 103 RLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSA--APGTLDLEARNYDGLTAL 160
Query: 602 HLASKWGYEGIARLLIEHGSE 622
H+A + +LL+E G++
Sbjct: 161 HVAVNTECQETVQLLLERGAD 181
Score = 46.4 bits (105), Expect = 5e-04
Identities = 43/160 (26%), Positives = 74/160 (46%), Gaps = 11/160 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGA---- 549
T LH+A I ++V L+ G+ A D + +A H A L LL S A
Sbjct: 88 TPLHLAVITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGTL 147
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCAN-ESGNTPLHLASKWG 608
++ +N D T LH+AVN C + + E R +I+ + +SG +PL A +
Sbjct: 148 DLEARNYDGLTALHVAVNT---ECQETVQLLLE---RGADIDAVDIKSGRSPLIHAVENN 201
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
+ +LL++HG+ + Q +A A +L ++++
Sbjct: 202 SLSMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRT 241
Score = 43.2 bits (97), Expect = 0.004
Identities = 40/118 (33%), Positives = 52/118 (44%), Gaps = 8/118 (6%)
Query: 765 DSNGFTALHYAARYG----LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
D +G T LH A G + N+ ++ N QTPLHLA I V+RLL
Sbjct: 46 DEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLL 105
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL-SYNP---DITLLNATEKTALAVA 874
+ GA+ A+D T H A E + + LL S P D+ N TAL VA
Sbjct: 106 VTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVA 163
>M31732-1|AAA51815.1| 446|Homo sapiens BCL3 protein.
Length = 446
Score = 74.5 bits (175), Expect = 1e-12
Identities = 50/164 (30%), Positives = 85/164 (51%), Gaps = 11/164 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGS----EINATDLNECSALHYASSRGHQNVLLML 544
D HG TA H+A H T + LL+ + ++ A + + +ALH A + Q + +L
Sbjct: 194 DRHGQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVAVNTECQETVQLL 253
Query: 545 LHSGANINQKNIDKN-TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L GA+I+ +I +PL AV N L V+ ++ +H N+N SG++ LH
Sbjct: 254 LERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLL---QHGA---NVNAQMYSGSSALHS 307
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
AS G + R L+ G++ SL+N ++ T A + R++ +L+
Sbjct: 308 ASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVARSRRVIDILR 351
Score = 65.3 bits (152), Expect = 9e-10
Identities = 42/138 (30%), Positives = 72/138 (52%), Gaps = 4/138 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRN-KKAQTPLHLAAINNKTVVIR 818
D+ + +G TALH A E +L+ A+++ + K ++PL A NN +++
Sbjct: 226 DLEARNYDGLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQ 285
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LLL +GAN+NA + ++ LH AS G + + L+ D +L N T L VA+ +
Sbjct: 286 LLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVARSR- 344
Query: 879 HLTIIDLIDNYANKYANT 896
+ID++ A + A+T
Sbjct: 345 --RVIDILRGKATRPAST 360
Score = 57.2 bits (132), Expect = 2e-07
Identities = 41/121 (33%), Positives = 63/121 (52%), Gaps = 7/121 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNE-CSALHYASSRGHQNVLLM 543
+ +R+ GLTALHVA V+ LLE G++I+A D+ S L +A +++ +
Sbjct: 227 LEARNYDGLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQL 286
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GAN+N + ++ LH A G L V+ ++ S K NC N+ TPL +
Sbjct: 287 LLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLK---NCHND---TPLMV 340
Query: 604 A 604
A
Sbjct: 341 A 341
Score = 49.6 bits (113), Expect = 5e-05
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Query: 557 DKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLL 616
D +TPLH+AV G+L V ++ + GR+++I N TPLHLA + RLL
Sbjct: 126 DGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDI--YNNLRQTPLHLAVITTLPSVVRLL 183
Query: 617 IEHGSEPSLQNSYHKTA 633
+ G+ P + + +TA
Sbjct: 184 VTAGASPMALDRHGQTA 200
Score = 46.4 bits (105), Expect = 5e-04
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEM----GSEINATDLNECSALHYASSRGHQNVL 541
T D G T LH+A + G V L+ + G E++ + + LH A +V+
Sbjct: 121 TRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVV 180
Query: 542 LMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L+ +GA+ + T HLA + C++A++ A + +++ N G T L
Sbjct: 181 RLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSA--APGTLDLEARNYDGLTAL 238
Query: 602 HLASKWGYEGIARLLIEHGSE 622
H+A + +LL+E G++
Sbjct: 239 HVAVNTECQETVQLLLERGAD 259
Score = 46.4 bits (105), Expect = 5e-04
Identities = 43/160 (26%), Positives = 74/160 (46%), Gaps = 11/160 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGA---- 549
T LH+A I ++V L+ G+ A D + +A H A L LL S A
Sbjct: 166 TPLHLAVITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGTL 225
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCAN-ESGNTPLHLASKWG 608
++ +N D T LH+AVN C + + E R +I+ + +SG +PL A +
Sbjct: 226 DLEARNYDGLTALHVAVNT---ECQETVQLLLE---RGADIDAVDIKSGRSPLIHAVENN 279
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
+ +LL++HG+ + Q +A A +L ++++
Sbjct: 280 SLSMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRT 319
Score = 43.2 bits (97), Expect = 0.004
Identities = 40/118 (33%), Positives = 52/118 (44%), Gaps = 8/118 (6%)
Query: 765 DSNGFTALHYAARYG----LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
D +G T LH A G + N+ ++ N QTPLHLA I V+RLL
Sbjct: 124 DEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLL 183
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL-SYNP---DITLLNATEKTALAVA 874
+ GA+ A+D T H A E + + LL S P D+ N TAL VA
Sbjct: 184 VTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVA 241
>BC064993-1|AAH64993.1| 446|Homo sapiens B-cell CLL/lymphoma 3
protein.
Length = 446
Score = 74.5 bits (175), Expect = 1e-12
Identities = 50/164 (30%), Positives = 85/164 (51%), Gaps = 11/164 (6%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGS----EINATDLNECSALHYASSRGHQNVLLML 544
D HG TA H+A H T + LL+ + ++ A + + +ALH A + Q + +L
Sbjct: 194 DRHGQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVAVNTECQETVQLL 253
Query: 545 LHSGANINQKNIDKN-TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L GA+I+ +I +PL AV N L V+ ++ +H N+N SG++ LH
Sbjct: 254 LERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLL---QHGA---NVNAQMYSGSSALHS 307
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLK 647
AS G + R L+ G++ SL+N ++ T A + R++ +L+
Sbjct: 308 ASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVARSRRVIDILR 351
Score = 65.3 bits (152), Expect = 9e-10
Identities = 42/138 (30%), Positives = 72/138 (52%), Gaps = 4/138 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRN-KKAQTPLHLAAINNKTVVIR 818
D+ + +G TALH A E +L+ A+++ + K ++PL A NN +++
Sbjct: 226 DLEARNYDGLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQ 285
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LLL +GAN+NA + ++ LH AS G + + L+ D +L N T L VA+ +
Sbjct: 286 LLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVARSR- 344
Query: 879 HLTIIDLIDNYANKYANT 896
+ID++ A + A+T
Sbjct: 345 --RVIDILRGKATRPAST 360
Score = 57.2 bits (132), Expect = 2e-07
Identities = 41/121 (33%), Positives = 63/121 (52%), Gaps = 7/121 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNE-CSALHYASSRGHQNVLLM 543
+ +R+ GLTALHVA V+ LLE G++I+A D+ S L +A +++ +
Sbjct: 227 LEARNYDGLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQL 286
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GAN+N + ++ LH A G L V+ ++ S K NC N+ TPL +
Sbjct: 287 LLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLK---NCHND---TPLMV 340
Query: 604 A 604
A
Sbjct: 341 A 341
Score = 49.6 bits (113), Expect = 5e-05
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Query: 557 DKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLL 616
D +TPLH+AV G+L V ++ + GR+++I N TPLHLA + RLL
Sbjct: 126 DGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDI--YNNLRQTPLHLAVITTLPSVVRLL 183
Query: 617 IEHGSEPSLQNSYHKTA 633
+ G+ P + + +TA
Sbjct: 184 VTAGASPMALDRHGQTA 200
Score = 46.4 bits (105), Expect = 5e-04
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEM----GSEINATDLNECSALHYASSRGHQNVL 541
T D G T LH+A + G V L+ + G E++ + + LH A +V+
Sbjct: 121 TRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVV 180
Query: 542 LMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPL 601
+L+ +GA+ + T HLA + C++A++ A + +++ N G T L
Sbjct: 181 RLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSA--APGTLDLEARNYDGLTAL 238
Query: 602 HLASKWGYEGIARLLIEHGSE 622
H+A + +LL+E G++
Sbjct: 239 HVAVNTECQETVQLLLERGAD 259
Score = 46.4 bits (105), Expect = 5e-04
Identities = 43/160 (26%), Positives = 74/160 (46%), Gaps = 11/160 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGA---- 549
T LH+A I ++V L+ G+ A D + +A H A L LL S A
Sbjct: 166 TPLHLAVITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGTL 225
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCAN-ESGNTPLHLASKWG 608
++ +N D T LH+AVN C + + E R +I+ + +SG +PL A +
Sbjct: 226 DLEARNYDGLTALHVAVNT---ECQETVQLLLE---RGADIDAVDIKSGRSPLIHAVENN 279
Query: 609 YEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
+ +LL++HG+ + Q +A A +L ++++
Sbjct: 280 SLSMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRT 319
Score = 43.2 bits (97), Expect = 0.004
Identities = 40/118 (33%), Positives = 52/118 (44%), Gaps = 8/118 (6%)
Query: 765 DSNGFTALHYAARYG----LDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
D +G T LH A G + N+ ++ N QTPLHLA I V+RLL
Sbjct: 124 DEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLL 183
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL-SYNP---DITLLNATEKTALAVA 874
+ GA+ A+D T H A E + + LL S P D+ N TAL VA
Sbjct: 184 VTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVA 241
>BC027033-1|AAH27033.1| 448|Homo sapiens hypothetical protein
MGC29891 protein.
Length = 448
Score = 74.5 bits (175), Expect = 1e-12
Identities = 38/128 (29%), Positives = 69/128 (53%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH AA+YG +L+ + + R K +TPLH+AA + ++ LL+ NGA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLID 887
NA D+ + T LH A+E + ++L+ Y D+ + +K+A +A +K + I+ ++
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQ 157
Query: 888 NYANKYAN 895
N
Sbjct: 158 EAMQNQVN 165
Score = 67.3 bits (157), Expect = 2e-10
Identities = 46/157 (29%), Positives = 80/157 (50%), Gaps = 10/157 (6%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A+ G+ V TL+ G+ TD S LH A+ GH + +LL +G + + +
Sbjct: 13 AARKGQDDEVRTLMANGAPFT-TDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVD 71
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH+A +GH H V+ ++ +G ++N + T LH A++ + + LLI+
Sbjct: 72 RTPLHMAAADGHAHIVELLV----RNG--ADVNAKDMLKMTALHWATERHHRDVVELLIK 125
Query: 619 HGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPN 652
+G++ + + K+AFD A +N IL +L+ N
Sbjct: 126 YGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQN 162
Score = 57.6 bits (133), Expect = 2e-07
Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 7/100 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A+ G A IVE L+ G+++NA D+ + +ALH+A+ R H++V+ +L+ GA+++
Sbjct: 73 TPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVVELLIKYGADVHA 132
Query: 554 -KNIDKNT-PLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
DK+ + L NN + ++ E ++N+N
Sbjct: 133 FSKFDKSAFDIALEKNNAEI-----LVILQEAMQNQVNVN 167
Score = 56.0 bits (129), Expect = 6e-07
Identities = 28/89 (31%), Positives = 51/89 (57%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A+ +G + E LL G +A + + LH A++ GH +++ +L+ +GA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
N K++ K T LH A H V+ +I +
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKY 126
Score = 34.7 bits (76), Expect = 1.5
Identities = 19/78 (24%), Positives = 41/78 (52%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D +TALH A+ +VE L++ G++++A + SA A + + +L++L
Sbjct: 97 VNAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVIL 156
Query: 545 LHSGANINQKNIDKNTPL 562
+ N N ++ P+
Sbjct: 157 QEAMQNQVNVNPERANPV 174
>AL691467-2|CAH73760.1| 410|Homo sapiens novel protein protein.
Length = 410
Score = 74.5 bits (175), Expect = 1e-12
Identities = 38/128 (29%), Positives = 69/128 (53%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH AA+YG +L+ + + R K +TPLH+AA + ++ LL+ NGA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLID 887
NA D+ + T LH A+E + ++L+ Y D+ + +K+A +A +K + I+ ++
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQ 157
Query: 888 NYANKYAN 895
N
Sbjct: 158 EAMQNQVN 165
Score = 67.3 bits (157), Expect = 2e-10
Identities = 46/157 (29%), Positives = 80/157 (50%), Gaps = 10/157 (6%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A+ G+ V TL+ G+ TD S LH A+ GH + +LL +G + + +
Sbjct: 13 AARKGQDDEVRTLMANGAPFT-TDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVD 71
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH+A +GH H V+ ++ +G ++N + T LH A++ + + LLI+
Sbjct: 72 RTPLHMAAADGHAHIVELLV----RNG--ADVNAKDMLKMTALHWATERHHRDVVELLIK 125
Query: 619 HGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPN 652
+G++ + + K+AFD A +N IL +L+ N
Sbjct: 126 YGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQN 162
Score = 57.6 bits (133), Expect = 2e-07
Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 7/100 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A+ G A IVE L+ G+++NA D+ + +ALH+A+ R H++V+ +L+ GA+++
Sbjct: 73 TPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVVELLIKYGADVHA 132
Query: 554 -KNIDKNT-PLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
DK+ + L NN + ++ E ++N+N
Sbjct: 133 FSKFDKSAFDIALEKNNAEI-----LVILQEAMQNQVNVN 167
Score = 56.0 bits (129), Expect = 6e-07
Identities = 28/89 (31%), Positives = 51/89 (57%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A+ +G + E LL G +A + + LH A++ GH +++ +L+ +GA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
N K++ K T LH A H V+ +I +
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKY 126
Score = 34.7 bits (76), Expect = 1.5
Identities = 19/78 (24%), Positives = 41/78 (52%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D +TALH A+ +VE L++ G++++A + SA A + + +L++L
Sbjct: 97 VNAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVIL 156
Query: 545 LHSGANINQKNIDKNTPL 562
+ N N ++ P+
Sbjct: 157 QEAMQNQVNVNPERANPV 174
>AL691467-1|CAH73759.1| 448|Homo sapiens novel protein protein.
Length = 448
Score = 74.5 bits (175), Expect = 1e-12
Identities = 38/128 (29%), Positives = 69/128 (53%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH AA+YG +L+ + + R K +TPLH+AA + ++ LL+ NGA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLID 887
NA D+ + T LH A+E + ++L+ Y D+ + +K+A +A +K + I+ ++
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQ 157
Query: 888 NYANKYAN 895
N
Sbjct: 158 EAMQNQVN 165
Score = 67.3 bits (157), Expect = 2e-10
Identities = 46/157 (29%), Positives = 80/157 (50%), Gaps = 10/157 (6%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A+ G+ V TL+ G+ TD S LH A+ GH + +LL +G + + +
Sbjct: 13 AARKGQDDEVRTLMANGAPFT-TDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVD 71
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH+A +GH H V+ ++ +G ++N + T LH A++ + + LLI+
Sbjct: 72 RTPLHMAAADGHAHIVELLV----RNG--ADVNAKDMLKMTALHWATERHHRDVVELLIK 125
Query: 619 HGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPN 652
+G++ + + K+AFD A +N IL +L+ N
Sbjct: 126 YGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQN 162
Score = 57.6 bits (133), Expect = 2e-07
Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 7/100 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A+ G A IVE L+ G+++NA D+ + +ALH+A+ R H++V+ +L+ GA+++
Sbjct: 73 TPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVVELLIKYGADVHA 132
Query: 554 -KNIDKNT-PLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
DK+ + L NN + ++ E ++N+N
Sbjct: 133 FSKFDKSAFDIALEKNNAEI-----LVILQEAMQNQVNVN 167
Score = 56.0 bits (129), Expect = 6e-07
Identities = 28/89 (31%), Positives = 51/89 (57%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A+ +G + E LL G +A + + LH A++ GH +++ +L+ +GA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
N K++ K T LH A H V+ +I +
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKY 126
Score = 34.7 bits (76), Expect = 1.5
Identities = 19/78 (24%), Positives = 41/78 (52%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D +TALH A+ +VE L++ G++++A + SA A + + +L++L
Sbjct: 97 VNAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVIL 156
Query: 545 LHSGANINQKNIDKNTPL 562
+ N N ++ P+
Sbjct: 157 QEAMQNQVNVNPERANPV 174
>AL592424-19|CAI16391.1| 410|Homo sapiens novel protein protein.
Length = 410
Score = 74.5 bits (175), Expect = 1e-12
Identities = 38/128 (29%), Positives = 69/128 (53%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH AA+YG +L+ + + R K +TPLH+AA + ++ LL+ NGA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLID 887
NA D+ + T LH A+E + ++L+ Y D+ + +K+A +A +K + I+ ++
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQ 157
Query: 888 NYANKYAN 895
N
Sbjct: 158 EAMQNQVN 165
Score = 67.3 bits (157), Expect = 2e-10
Identities = 46/157 (29%), Positives = 80/157 (50%), Gaps = 10/157 (6%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A+ G+ V TL+ G+ TD S LH A+ GH + +LL +G + + +
Sbjct: 13 AARKGQDDEVRTLMANGAPFT-TDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVD 71
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH+A +GH H V+ ++ +G ++N + T LH A++ + + LLI+
Sbjct: 72 RTPLHMAAADGHAHIVELLV----RNG--ADVNAKDMLKMTALHWATERHHRDVVELLIK 125
Query: 619 HGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPN 652
+G++ + + K+AFD A +N IL +L+ N
Sbjct: 126 YGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQN 162
Score = 57.6 bits (133), Expect = 2e-07
Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 7/100 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A+ G A IVE L+ G+++NA D+ + +ALH+A+ R H++V+ +L+ GA+++
Sbjct: 73 TPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVVELLIKYGADVHA 132
Query: 554 -KNIDKNT-PLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
DK+ + L NN + ++ E ++N+N
Sbjct: 133 FSKFDKSAFDIALEKNNAEI-----LVILQEAMQNQVNVN 167
Score = 56.0 bits (129), Expect = 6e-07
Identities = 28/89 (31%), Positives = 51/89 (57%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A+ +G + E LL G +A + + LH A++ GH +++ +L+ +GA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
N K++ K T LH A H V+ +I +
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKY 126
Score = 34.7 bits (76), Expect = 1.5
Identities = 19/78 (24%), Positives = 41/78 (52%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D +TALH A+ +VE L++ G++++A + SA A + + +L++L
Sbjct: 97 VNAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVIL 156
Query: 545 LHSGANINQKNIDKNTPL 562
+ N N ++ P+
Sbjct: 157 QEAMQNQVNVNPERANPV 174
>AL592424-18|CAI16392.1| 448|Homo sapiens novel protein protein.
Length = 448
Score = 74.5 bits (175), Expect = 1e-12
Identities = 38/128 (29%), Positives = 69/128 (53%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH AA+YG +L+ + + R K +TPLH+AA + ++ LL+ NGA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLID 887
NA D+ + T LH A+E + ++L+ Y D+ + +K+A +A +K + I+ ++
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQ 157
Query: 888 NYANKYAN 895
N
Sbjct: 158 EAMQNQVN 165
Score = 67.3 bits (157), Expect = 2e-10
Identities = 46/157 (29%), Positives = 80/157 (50%), Gaps = 10/157 (6%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A+ G+ V TL+ G+ TD S LH A+ GH + +LL +G + + +
Sbjct: 13 AARKGQDDEVRTLMANGAPFT-TDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVD 71
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH+A +GH H V+ ++ +G ++N + T LH A++ + + LLI+
Sbjct: 72 RTPLHMAAADGHAHIVELLV----RNG--ADVNAKDMLKMTALHWATERHHRDVVELLIK 125
Query: 619 HGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPN 652
+G++ + + K+AFD A +N IL +L+ N
Sbjct: 126 YGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQN 162
Score = 57.6 bits (133), Expect = 2e-07
Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 7/100 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A+ G A IVE L+ G+++NA D+ + +ALH+A+ R H++V+ +L+ GA+++
Sbjct: 73 TPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVVELLIKYGADVHA 132
Query: 554 -KNIDKNT-PLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
DK+ + L NN + ++ E ++N+N
Sbjct: 133 FSKFDKSAFDIALEKNNAEI-----LVILQEAMQNQVNVN 167
Score = 56.0 bits (129), Expect = 6e-07
Identities = 28/89 (31%), Positives = 51/89 (57%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A+ +G + E LL G +A + + LH A++ GH +++ +L+ +GA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
N K++ K T LH A H V+ +I +
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKY 126
Score = 34.7 bits (76), Expect = 1.5
Identities = 19/78 (24%), Positives = 41/78 (52%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D +TALH A+ +VE L++ G++++A + SA A + + +L++L
Sbjct: 97 VNAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVIL 156
Query: 545 LHSGANINQKNIDKNTPL 562
+ N N ++ P+
Sbjct: 157 QEAMQNQVNVNPERANPV 174
>AL590133-27|CAI13351.1| 448|Homo sapiens novel protein protein.
Length = 448
Score = 74.5 bits (175), Expect = 1e-12
Identities = 38/128 (29%), Positives = 69/128 (53%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH AA+YG +L+ + + R K +TPLH+AA + ++ LL+ NGA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLID 887
NA D+ + T LH A+E + ++L+ Y D+ + +K+A +A +K + I+ ++
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQ 157
Query: 888 NYANKYAN 895
N
Sbjct: 158 EAMQNQVN 165
Score = 67.3 bits (157), Expect = 2e-10
Identities = 46/157 (29%), Positives = 80/157 (50%), Gaps = 10/157 (6%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A+ G+ V TL+ G+ TD S LH A+ GH + +LL +G + + +
Sbjct: 13 AARKGQDDEVRTLMANGAPFT-TDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVD 71
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH+A +GH H V+ ++ +G ++N + T LH A++ + + LLI+
Sbjct: 72 RTPLHMAAADGHAHIVELLV----RNG--ADVNAKDMLKMTALHWATERHHRDVVELLIK 125
Query: 619 HGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPN 652
+G++ + + K+AFD A +N IL +L+ N
Sbjct: 126 YGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQN 162
Score = 57.6 bits (133), Expect = 2e-07
Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 7/100 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A+ G A IVE L+ G+++NA D+ + +ALH+A+ R H++V+ +L+ GA+++
Sbjct: 73 TPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVVELLIKYGADVHA 132
Query: 554 -KNIDKNT-PLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
DK+ + L NN + ++ E ++N+N
Sbjct: 133 FSKFDKSAFDIALEKNNAEI-----LVILQEAMQNQVNVN 167
Score = 56.0 bits (129), Expect = 6e-07
Identities = 28/89 (31%), Positives = 51/89 (57%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A+ +G + E LL G +A + + LH A++ GH +++ +L+ +GA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
N K++ K T LH A H V+ +I +
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKY 126
Score = 34.7 bits (76), Expect = 1.5
Identities = 19/78 (24%), Positives = 41/78 (52%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D +TALH A+ +VE L++ G++++A + SA A + + +L++L
Sbjct: 97 VNAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVIL 156
Query: 545 LHSGANINQKNIDKNTPL 562
+ N N ++ P+
Sbjct: 157 QEAMQNQVNVNPERANPV 174
>AL590133-26|CAI13352.1| 410|Homo sapiens novel protein protein.
Length = 410
Score = 74.5 bits (175), Expect = 1e-12
Identities = 38/128 (29%), Positives = 69/128 (53%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH AA+YG +L+ + + R K +TPLH+AA + ++ LL+ NGA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLID 887
NA D+ + T LH A+E + ++L+ Y D+ + +K+A +A +K + I+ ++
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQ 157
Query: 888 NYANKYAN 895
N
Sbjct: 158 EAMQNQVN 165
Score = 67.3 bits (157), Expect = 2e-10
Identities = 46/157 (29%), Positives = 80/157 (50%), Gaps = 10/157 (6%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A+ G+ V TL+ G+ TD S LH A+ GH + +LL +G + + +
Sbjct: 13 AARKGQDDEVRTLMANGAPFT-TDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVD 71
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
TPLH+A +GH H V+ ++ +G ++N + T LH A++ + + LLI+
Sbjct: 72 RTPLHMAAADGHAHIVELLV----RNG--ADVNAKDMLKMTALHWATERHHRDVVELLIK 125
Query: 619 HGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPN 652
+G++ + + K+AFD A +N IL +L+ N
Sbjct: 126 YGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQN 162
Score = 57.6 bits (133), Expect = 2e-07
Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 7/100 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A+ G A IVE L+ G+++NA D+ + +ALH+A+ R H++V+ +L+ GA+++
Sbjct: 73 TPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVVELLIKYGADVHA 132
Query: 554 -KNIDKNT-PLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
DK+ + L NN + ++ E ++N+N
Sbjct: 133 FSKFDKSAFDIALEKNNAEI-----LVILQEAMQNQVNVN 167
Score = 56.0 bits (129), Expect = 6e-07
Identities = 28/89 (31%), Positives = 51/89 (57%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A+ +G + E LL G +A + + LH A++ GH +++ +L+ +GA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
N K++ K T LH A H V+ +I +
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKY 126
Score = 34.7 bits (76), Expect = 1.5
Identities = 19/78 (24%), Positives = 41/78 (52%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D +TALH A+ +VE L++ G++++A + SA A + + +L++L
Sbjct: 97 VNAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVIL 156
Query: 545 LHSGANINQKNIDKNTPL 562
+ N N ++ P+
Sbjct: 157 QEAMQNQVNVNPERANPV 174
>AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 518
Score = 74.5 bits (175), Expect = 1e-12
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +LH AS A I++ LL G+ D + L A+ G L +L+ SGAN+
Sbjct: 146 GWNSLHQASFQDNAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 205
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + +DK TPL +A GH CV+ ++ SG ++ C +S P+H A++ G+
Sbjct: 206 NCQALDKATPLFIAAQEGHTKCVELLL----SSGADPDLYCNEDSWQLPIHAAAQMGHTK 261
Query: 612 IARLLI 617
I LLI
Sbjct: 262 ILDLLI 267
Score = 64.5 bits (150), Expect = 2e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 7/136 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G ALH+A+ G IV+ LLE G++ NAT L E + L A G +VL +LL GAN+
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Query: 552 N-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N ++ LH A + +K ++ + N C ++ G TPL +A+++G
Sbjct: 139 NGSHSMCGWNSLHQASFQDNAEIIKLLL------RKGANKECQDDFGITPLFVAAQYGKL 192
Query: 611 GIARLLIEHGSEPSLQ 626
+LI G+ + Q
Sbjct: 193 ESLSILISSGANVNCQ 208
Score = 59.3 bits (137), Expect = 6e-08
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+ +LH A+ E +L+ AN C++ TPL +AA K + +L+ +GAN+
Sbjct: 146 GWNSLHQASFQDNAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 205
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLS--YNPDITLLNATEKTALAVAKDKVHLTIIDL 885
N + + TPL A++ G+ ++LLS +PD+ + + + A H I+DL
Sbjct: 206 NCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDL 265
Query: 886 IDNYANKYANT 896
+ N+ +T
Sbjct: 266 LIPLTNRACDT 276
Score = 54.8 bits (126), Expect = 1e-06
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 741 HPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKK 800
H EC +S ++ + + GF ALH AA G + IL+ A+ N +
Sbjct: 53 HNSVECLQMLINADSSENY-IKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLE 111
Query: 801 AQTPLHLAAINNKTVVIRLLLDNGANIN-AIDVARNTPLHDASETGNIGAAKILL 854
TPL LA N + V+RLLL +GAN+N + + LH AS N K+LL
Sbjct: 112 ETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQDNAEIIKLLL 166
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T L AA+YG E +ILI + ANVNC+ TPL +AA T + LLL +G
Sbjct: 176 DDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235
Query: 825 A--NINAIDVARNTPLHDASETGNIGAAKILL 854
A ++ + + P+H A++ G+ +L+
Sbjct: 236 ADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G+T L VA+ +GK + L+ G+ +N L++ + L A+ GH + +LL S
Sbjct: 175 QDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSS 234
Query: 548 GANIN-QKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+ + N D P+H A GH + +I + R + S P++ A
Sbjct: 235 GADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPL---TNRACDTGLNKVS---PVYSAV 288
Query: 606 KWGYEGIARLLIEHGSEPSLQ 626
G+E +L+ +G P Q
Sbjct: 289 FGGHEDCLEILLRNGYSPDAQ 309
Score = 50.0 bits (114), Expect = 4e-05
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQT---PLHLAAINNKTVVI 817
V+V D+ G+ +H AA + E +LI ++ N K LHLAA ++
Sbjct: 36 VDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIV 95
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++LL+ GA+ NA + TPL A E G I ++LL + ++
Sbjct: 96 QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 526 CSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
CS + A+ G+ VL LL G +++ + P+H A + + C++ +I A+ S
Sbjct: 11 CSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLIN-ADSSE 69
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPS 624
I + G LHLA+ G+ I ++L+E G++P+
Sbjct: 70 NYIKMK--TFEGFCALHLAASQGHWKIVQILLEAGADPN 106
Score = 33.9 bits (74), Expect = 2.6
Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 3/115 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AAR G + L+ +V+ + + P+H AA +N +++L++ ++ N I +
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 835 ---NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LH A+ G+ +ILL D E T L +A + + ++ L+
Sbjct: 77 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLL 131
>AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens
cDNA FLJ25613 fis, clone STM01546. ).
Length = 353
Score = 74.5 bits (175), Expect = 1e-12
Identities = 46/153 (30%), Positives = 74/153 (48%), Gaps = 6/153 (3%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ +RD T LHVA+ + E L + S +N D + SALH+A GH + +L
Sbjct: 118 VNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLL 177
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
L+ GA++N + + PLH A GHL +K ++ R ++ C + G LH A
Sbjct: 178 LNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLV------ARGADLGCKDRKGYGLLHTA 231
Query: 605 SKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
+ G + + L+ G+E N++ TA A
Sbjct: 232 AASGQIEVVKYLLRMGAEIDEPNAFGNTALHIA 264
Score = 68.9 bits (161), Expect = 7e-11
Identities = 42/114 (36%), Positives = 61/114 (53%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+NV D +G +ALH+A G E N+L+ A++N +KK + PLH AA V++LL
Sbjct: 151 LNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLL 210
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
+ GA++ D LH A+ +G I K LL +I NA TAL +A
Sbjct: 211 VARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIA 264
Score = 65.7 bits (153), Expect = 7e-10
Identities = 44/139 (31%), Positives = 65/139 (46%), Gaps = 6/139 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G +ALH A G V LL G+ +N D E LH+A+ GH VL +L+ G
Sbjct: 155 DRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARG 214
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A++ K+ LH A +G + VK ++ I+ N GNT LH+A G
Sbjct: 215 ADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAE------IDEPNAFGNTALHIACYLG 268
Query: 609 YEGIARLLIEHGSEPSLQN 627
+ +A L+ G+ + N
Sbjct: 269 QDAVAIELVNAGANVNQPN 287
Score = 63.3 bits (147), Expect = 4e-09
Identities = 38/130 (29%), Positives = 65/130 (50%)
Query: 757 TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVV 816
T +VN D+ LH AA ++ +L+ + A+VN R+K QTPLH+AA N T
Sbjct: 81 TGANVNAKDTLWLAPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKC 140
Query: 817 IRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
L +++N D + + LH A +G++ +LL+ + + + E+ L A
Sbjct: 141 AEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAF 200
Query: 877 KVHLTIIDLI 886
HL ++ L+
Sbjct: 201 LGHLEVLKLL 210
Score = 61.7 bits (143), Expect = 1e-08
Identities = 35/93 (37%), Positives = 54/93 (58%), Gaps = 3/93 (3%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G LH A+ G+ +V+ LL MG+EI+ + +ALH A G V + L+++
Sbjct: 220 KDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNA 279
Query: 548 GANINQKNIDKNTPLHLAV--NNGHLHCVKAII 578
GAN+NQ N TPLH+A NG L C++ ++
Sbjct: 280 GANVNQPNDKGFTPLHVAAVSTNGAL-CLELLV 311
Score = 58.4 bits (135), Expect = 1e-07
Identities = 41/136 (30%), Positives = 65/136 (47%), Gaps = 1/136 (0%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
+NVCD LH+AA G E +L+ A++ C+++K LH AA + + V++ L
Sbjct: 184 LNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYL 243
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHL 880
L GA I+ + NT LH A G A L++ ++ N T L VA +
Sbjct: 244 LRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNG 303
Query: 881 TI-IDLIDNYANKYAN 895
+ ++L+ N Y N
Sbjct: 304 ALCLELLVNNGAFYFN 319
Score = 55.6 bits (128), Expect = 7e-07
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 6/133 (4%)
Query: 515 GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCV 574
G+ +NA D + LH A++ ++ VL +LL A++N ++ TPLH+A N C
Sbjct: 82 GANVNAKDTLWLAPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCA 141
Query: 575 KAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAF 634
+A+ ++N A+ SG + LH A G+ LL+ G+ ++ + +
Sbjct: 142 EALAPLLS------SLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPL 195
Query: 635 DYAHNLRILQVLK 647
+A L L+VLK
Sbjct: 196 HWAAFLGHLEVLK 208
Score = 55.6 bits (128), Expect = 7e-07
Identities = 35/110 (31%), Positives = 56/110 (50%), Gaps = 6/110 (5%)
Query: 496 LHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKN 555
LH A+ G +++ L+ G+++ D LH A++ G V+ LL GA I++ N
Sbjct: 195 LHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPN 254
Query: 556 IDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
NT LH+A G A+ ++G N+N N+ G TPLH+A+
Sbjct: 255 AFGNTALHIACYLGQ----DAVAIELVNAGA--NVNQPNDKGFTPLHVAA 298
Score = 49.6 bits (113), Expect = 5e-05
Identities = 31/97 (31%), Positives = 49/97 (50%)
Query: 792 ANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAK 851
ANVN ++ PLH AA + V+ LLL + A++NA D TPLH A+ A+
Sbjct: 83 ANVNAKDTLWLAPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAE 142
Query: 852 ILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLIDN 888
L + + + + ++AL A HL ++L+ N
Sbjct: 143 ALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLN 179
Score = 49.6 bits (113), Expect = 5e-05
Identities = 29/101 (28%), Positives = 49/101 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN D T LH AA + L +++N ++ ++ LH A + + L
Sbjct: 117 DVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNL 176
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
LL+ GA++N D PLH A+ G++ K+L++ D+
Sbjct: 177 LLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADL 217
Score = 48.4 bits (110), Expect = 1e-04
Identities = 34/142 (23%), Positives = 68/142 (47%), Gaps = 6/142 (4%)
Query: 481 TCPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV 540
T + ++D+ L LH A+ ++ LL +++NA D + LH A++
Sbjct: 81 TGANVNAKDTLWLAPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKC 140
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
L +++N + + LH AV++GHL V ++ + G +N+ ++ P
Sbjct: 141 AEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLL----NKGASLNV--CDKKERQP 194
Query: 601 LHLASKWGYEGIARLLIEHGSE 622
LH A+ G+ + +LL+ G++
Sbjct: 195 LHWAAFLGHLEVLKLLVARGAD 216
Score = 43.2 bits (97), Expect = 0.004
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+ D G+ LH AA G E L+ A ++ N T LH+A + V
Sbjct: 216 DLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIE 275
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYN 857
L++ GAN+N + TPLH A+ + N GA + L N
Sbjct: 276 LVNAGANVNQPNDKGFTPLHVAAVSTN-GALCLELLVN 312
Score = 33.9 bits (74), Expect = 2.6
Identities = 18/54 (33%), Positives = 29/54 (53%)
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
+ GAN+NA D PLH A+ + N +LL+++ D+ + +T L VA
Sbjct: 79 IPTGANVNAKDTLWLAPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVA 132
>AB075861-1|BAB85567.1| 863|Homo sapiens KIAA1981 protein protein.
Length = 863
Score = 74.5 bits (175), Expect = 1e-12
Identities = 45/148 (30%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Query: 486 TSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLL 545
T D G +A H+A++ G A+ +E ++ GS + +TD +ALH A+ GH L LL
Sbjct: 67 TKLDPEGKSAFHLAAMRGAASCLEVMIAHGSNVMSTDGAGYNALHLAAKYGHPQCLKQLL 126
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
+ ++ + T LH A G L C + + F H +N + SG TPL +A+
Sbjct: 127 QASCVVDVVDSSGWTALHHAAAGGCLSCSEVLCSFKAH------LNPQDRSGATPLIIAA 180
Query: 606 KWGYEGIARLLIEHGSEPSLQNSYHKTA 633
+ + + RLL++ G+ + Q+ +TA
Sbjct: 181 QMCHTDLCRLLLQQGAAANDQDLQGRTA 208
Score = 57.6 bits (133), Expect = 2e-07
Identities = 48/146 (32%), Positives = 73/146 (50%), Gaps = 9/146 (6%)
Query: 741 HPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKK 800
HP C Q + SC V+V DS+G+TALH+AA G +L +A++N +++
Sbjct: 118 HPQCLKQLLQA---SCV---VDVVDSSGWTALHHAAAGGCLSCSEVLCSFKAHLNPQDRS 171
Query: 801 AQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
TPL +AA T + RLLL GA N D+ T L A E + ++LL
Sbjct: 172 GATPLIIAAQMCHTDLCRLLLQQGAAANDQDLQGRTALMLACEGASPETVEVLLQGGAQP 231
Query: 861 TLLNATEKTAL---AVAKDKVHLTII 883
+ +A + A A+A DK+ L ++
Sbjct: 232 GITDALGQDAAHYGALAGDKLILHLL 257
Score = 48.8 bits (111), Expect = 8e-05
Identities = 30/122 (24%), Positives = 54/122 (44%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G +A H AA G ++I + +NV + LHLAA ++ LL
Sbjct: 70 DPEGKSAFHLAAMRGAASCLEVMIAHGSNVMSTDGAGYNALHLAAKYGHPQCLKQLLQAS 129
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIID 884
++ +D + T LH A+ G + +++L S+ + + + T L +A H +
Sbjct: 130 CVVDVVDSSGWTALHHAAAGGCLSCSEVLCSFKAHLNPQDRSGATPLIIAAQMCHTDLCR 189
Query: 885 LI 886
L+
Sbjct: 190 LL 191
Score = 39.1 bits (87), Expect = 0.068
Identities = 30/110 (27%), Positives = 48/110 (43%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G+ ALH AA+YG + L+ V+ + T LH AA +L
Sbjct: 103 DGAGYNALHLAAKYGHPQCLKQLLQASCVVDVVDSSGWTALHHAAAGGCLSCSEVLCSFK 162
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
A++N D + TPL A++ + ++LL + +TAL +A
Sbjct: 163 AHLNPQDRSGATPLIIAAQMCHTDLCRLLLQQGAAANDQDLQGRTALMLA 212
>BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein.
Length = 553
Score = 74.1 bits (174), Expect = 2e-12
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +LH AS A I++ LL G+ D + L A+ G L +L+ SGAN+
Sbjct: 181 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 240
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + +DK TPL +A GH CV+ ++ SG ++ C +S P+H A++ G+
Sbjct: 241 NCQALDKATPLFIAAQEGHTKCVELLL----SSGADPDLYCNEDSWQLPIHAAAQMGHTK 296
Query: 612 IARLLI 617
I LLI
Sbjct: 297 ILDLLI 302
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 7/136 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G ALH+A+ G IV+ LLE G++ NAT L E + L A G +VL +LL GAN+
Sbjct: 114 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 173
Query: 552 N-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N ++ LH A + +K ++ + N C ++ G TPL +A+++G
Sbjct: 174 NGSHSMCGWNSLHQASFQENAEIIKLLL------RKGANKECQDDFGITPLFVAAQYGKL 227
Query: 611 GIARLLIEHGSEPSLQ 626
+LI G+ + Q
Sbjct: 228 ESLSILISSGANVNCQ 243
Score = 58.8 bits (136), Expect = 8e-08
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+ +LH A+ E +L+ AN C++ TPL +AA K + +L+ +GAN+
Sbjct: 181 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 240
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLS--YNPDITLLNATEKTALAVAKDKVHLTIIDL 885
N + + TPL A++ G+ ++LLS +PD+ + + + A H I+DL
Sbjct: 241 NCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDL 300
Query: 886 IDNYANKYANT 896
+ N+ +T
Sbjct: 301 LIPLTNRACDT 311
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T L AA+YG E +ILI + ANVNC+ TPL +AA T + LLL +G
Sbjct: 211 DDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 270
Query: 825 A--NINAIDVARNTPLHDASETGNIGAAKILL 854
A ++ + + P+H A++ G+ +L+
Sbjct: 271 ADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 302
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 741 HPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKK 800
H EC +S ++ + + GF ALH AA G + IL+ A+ N +
Sbjct: 88 HNSVECLQMLINADSSENY-IKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLE 146
Query: 801 AQTPLHLAAINNKTVVIRLLLDNGANIN-AIDVARNTPLHDASETGNIGAAKILL 854
TPL LA N + V+RLLL +GAN+N + + LH AS N K+LL
Sbjct: 147 ETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLL 201
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G+T L VA+ +GK + L+ G+ +N L++ + L A+ GH + +LL S
Sbjct: 210 QDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSS 269
Query: 548 GANIN-QKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+ + N D P+H A GH + +I + R + S P++ A
Sbjct: 270 GADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPL---TNRACDTGLNKVS---PVYSAV 323
Query: 606 KWGYEGIARLLIEHGSEPSLQ 626
G+E +L+ +G P Q
Sbjct: 324 FGGHEDCLEILLRNGYSPDAQ 344
Score = 50.0 bits (114), Expect = 4e-05
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQT---PLHLAAINNKTVVI 817
V+V D+ G+ +H AA + E +LI ++ N K LHLAA ++
Sbjct: 71 VDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIV 130
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++LL+ GA+ NA + TPL A E G I ++LL + ++
Sbjct: 131 QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 173
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 526 CSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
CS + A+ G+ VL LL G +++ + P+H A + + C++ +I A+ S
Sbjct: 46 CSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLIN-ADSSE 104
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPS 624
I + G LHLA+ G+ I ++L+E G++P+
Sbjct: 105 NYIKMK--TFEGFCALHLAASQGHWKIVQILLEAGADPN 141
Score = 33.9 bits (74), Expect = 2.6
Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 3/115 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AAR G + L+ +V+ + + P+H AA +N +++L++ ++ N I +
Sbjct: 52 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 111
Query: 835 ---NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LH A+ G+ +ILL D E T L +A + + ++ L+
Sbjct: 112 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLL 166
>BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing 3 protein.
Length = 518
Score = 74.1 bits (174), Expect = 2e-12
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +LH AS A I++ LL G+ D + L A+ G L +L+ SGAN+
Sbjct: 146 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 205
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + +DK TPL +A GH CV+ ++ SG ++ C +S P+H A++ G+
Sbjct: 206 NCQALDKATPLFIAAQEGHTKCVELLL----SSGADPDLYCNEDSWQLPIHAAAQMGHTK 261
Query: 612 IARLLI 617
I LLI
Sbjct: 262 ILDLLI 267
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 7/136 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G ALH+A+ G IV+ LLE G++ NAT L E + L A G +VL +LL GAN+
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Query: 552 N-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N ++ LH A + +K ++ + N C ++ G TPL +A+++G
Sbjct: 139 NGSHSMCGWNSLHQASFQENAEIIKLLL------RKGANKECQDDFGITPLFVAAQYGKL 192
Query: 611 GIARLLIEHGSEPSLQ 626
+LI G+ + Q
Sbjct: 193 ESLSILISSGANVNCQ 208
Score = 58.8 bits (136), Expect = 8e-08
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+ +LH A+ E +L+ AN C++ TPL +AA K + +L+ +GAN+
Sbjct: 146 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 205
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLS--YNPDITLLNATEKTALAVAKDKVHLTIIDL 885
N + + TPL A++ G+ ++LLS +PD+ + + + A H I+DL
Sbjct: 206 NCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDL 265
Query: 886 IDNYANKYANT 896
+ N+ +T
Sbjct: 266 LIPLTNRACDT 276
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T L AA+YG E +ILI + ANVNC+ TPL +AA T + LLL +G
Sbjct: 176 DDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235
Query: 825 A--NINAIDVARNTPLHDASETGNIGAAKILL 854
A ++ + + P+H A++ G+ +L+
Sbjct: 236 ADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 741 HPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKK 800
H EC +S ++ + + GF ALH AA G + IL+ A+ N +
Sbjct: 53 HNSVECLQMLINADSSENY-IKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLE 111
Query: 801 AQTPLHLAAINNKTVVIRLLLDNGANIN-AIDVARNTPLHDASETGNIGAAKILL 854
TPL LA N + V+RLLL +GAN+N + + LH AS N K+LL
Sbjct: 112 ETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLL 166
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G+T L VA+ +GK + L+ G+ +N L++ + L A+ GH + +LL S
Sbjct: 175 QDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSS 234
Query: 548 GANIN-QKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+ + N D P+H A GH + +I + R + S P++ A
Sbjct: 235 GADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPL---TNRACDTGLNKVS---PVYSAV 288
Query: 606 KWGYEGIARLLIEHGSEPSLQ 626
G+E +L+ +G P Q
Sbjct: 289 FGGHEDCLEILLRNGYSPDAQ 309
Score = 50.0 bits (114), Expect = 4e-05
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQT---PLHLAAINNKTVVI 817
V+V D+ G+ +H AA + E +LI ++ N K LHLAA ++
Sbjct: 36 VDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIV 95
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++LL+ GA+ NA + TPL A E G I ++LL + ++
Sbjct: 96 QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 526 CSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
CS + A+ G+ VL LL G +++ + P+H A + + C++ +I A+ S
Sbjct: 11 CSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLIN-ADSSE 69
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPS 624
I + G LHLA+ G+ I ++L+E G++P+
Sbjct: 70 NYIKMK--TFEGFCALHLAASQGHWKIVQILLEAGADPN 106
Score = 33.9 bits (74), Expect = 2.6
Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 3/115 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AAR G + L+ +V+ + + P+H AA +N +++L++ ++ N I +
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 835 ---NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LH A+ G+ +ILL D E T L +A + + ++ L+
Sbjct: 77 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLL 131
>BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing 3 protein.
Length = 518
Score = 74.1 bits (174), Expect = 2e-12
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +LH AS A I++ LL G+ D + L A+ G L +L+ SGAN+
Sbjct: 146 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 205
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + +DK TPL +A GH CV+ ++ SG ++ C +S P+H A++ G+
Sbjct: 206 NCQALDKATPLFIAAQEGHTKCVELLL----SSGADPDLYCNEDSWQLPIHAAAQMGHTK 261
Query: 612 IARLLI 617
I LLI
Sbjct: 262 ILDLLI 267
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 7/136 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G ALH+A+ G IV+ LLE G++ NAT L E + L A G +VL +LL GAN+
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Query: 552 N-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N ++ LH A + +K ++ + N C ++ G TPL +A+++G
Sbjct: 139 NGSHSMCGWNSLHQASFQENAEIIKLLL------RKGANKECQDDFGITPLFVAAQYGKL 192
Query: 611 GIARLLIEHGSEPSLQ 626
+LI G+ + Q
Sbjct: 193 ESLSILISSGANVNCQ 208
Score = 58.8 bits (136), Expect = 8e-08
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+ +LH A+ E +L+ AN C++ TPL +AA K + +L+ +GAN+
Sbjct: 146 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 205
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLS--YNPDITLLNATEKTALAVAKDKVHLTIIDL 885
N + + TPL A++ G+ ++LLS +PD+ + + + A H I+DL
Sbjct: 206 NCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDL 265
Query: 886 IDNYANKYANT 896
+ N+ +T
Sbjct: 266 LIPLTNRACDT 276
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T L AA+YG E +ILI + ANVNC+ TPL +AA T + LLL +G
Sbjct: 176 DDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235
Query: 825 A--NINAIDVARNTPLHDASETGNIGAAKILL 854
A ++ + + P+H A++ G+ +L+
Sbjct: 236 ADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 741 HPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKK 800
H EC +S ++ + + GF ALH AA G + IL+ A+ N +
Sbjct: 53 HNSVECLQMLINADSSENY-IKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLE 111
Query: 801 AQTPLHLAAINNKTVVIRLLLDNGANIN-AIDVARNTPLHDASETGNIGAAKILL 854
TPL LA N + V+RLLL +GAN+N + + LH AS N K+LL
Sbjct: 112 ETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLL 166
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G+T L VA+ +GK + L+ G+ +N L++ + L A+ GH + +LL S
Sbjct: 175 QDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSS 234
Query: 548 GANIN-QKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+ + N D P+H A GH + +I + R + S P++ A
Sbjct: 235 GADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPL---TNRACDTGLNKVS---PVYSAV 288
Query: 606 KWGYEGIARLLIEHGSEPSLQ 626
G+E +L+ +G P Q
Sbjct: 289 FGGHEDCLEILLRNGYSPDAQ 309
Score = 50.0 bits (114), Expect = 4e-05
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQT---PLHLAAINNKTVVI 817
V+V D+ G+ +H AA + E +LI ++ N K LHLAA ++
Sbjct: 36 VDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIV 95
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++LL+ GA+ NA + TPL A E G I ++LL + ++
Sbjct: 96 QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 526 CSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
CS + A+ G+ VL LL G +++ + P+H A + + C++ +I A+ S
Sbjct: 11 CSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLIN-ADSSE 69
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPS 624
I + G LHLA+ G+ I ++L+E G++P+
Sbjct: 70 NYIKMK--TFEGFCALHLAASQGHWKIVQILLEAGADPN 106
Score = 33.9 bits (74), Expect = 2.6
Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 3/115 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AAR G + L+ +V+ + + P+H AA +N +++L++ ++ N I +
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 835 ---NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LH A+ G+ +ILL D E T L +A + + ++ L+
Sbjct: 77 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLL 131
>AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 512
Score = 74.1 bits (174), Expect = 2e-12
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +LH AS A I++ LL G+ D + L A+ G L +L+ SGAN+
Sbjct: 140 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 199
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + +DK TPL +A GH CV+ ++ SG ++ C +S P+H A++ G+
Sbjct: 200 NCQALDKATPLFIAAQEGHTKCVELLL----SSGADPDLYCNEDSWQLPIHAAAQMGHTK 255
Query: 612 IARLLI 617
I LLI
Sbjct: 256 ILDLLI 261
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 7/136 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G ALH+A+ G IV+ LLE G++ NAT L E + L A G +VL +LL GAN+
Sbjct: 73 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 132
Query: 552 N-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N ++ LH A + +K ++ + N C ++ G TPL +A+++G
Sbjct: 133 NGSHSMCGWNSLHQASFQENAEIIKLLL------RKGANKECQDDFGITPLFVAAQYGKL 186
Query: 611 GIARLLIEHGSEPSLQ 626
+LI G+ + Q
Sbjct: 187 ESLSILISSGANVNCQ 202
Score = 58.8 bits (136), Expect = 8e-08
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+ +LH A+ E +L+ AN C++ TPL +AA K + +L+ +GAN+
Sbjct: 140 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 199
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLS--YNPDITLLNATEKTALAVAKDKVHLTIIDL 885
N + + TPL A++ G+ ++LLS +PD+ + + + A H I+DL
Sbjct: 200 NCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDL 259
Query: 886 IDNYANKYANT 896
+ N+ +T
Sbjct: 260 LIPLTNRACDT 270
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T L AA+YG E +ILI + ANVNC+ TPL +AA T + LLL +G
Sbjct: 170 DDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 229
Query: 825 A--NINAIDVARNTPLHDASETGNIGAAKILL 854
A ++ + + P+H A++ G+ +L+
Sbjct: 230 ADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 261
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 741 HPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKK 800
H EC +S ++ + + GF ALH AA G + IL+ A+ N +
Sbjct: 47 HNSVECLQMLINADSSENY-IKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLE 105
Query: 801 AQTPLHLAAINNKTVVIRLLLDNGANIN-AIDVARNTPLHDASETGNIGAAKILL 854
TPL LA N + V+RLLL +GAN+N + + LH AS N K+LL
Sbjct: 106 ETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLL 160
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G+T L VA+ +GK + L+ G+ +N L++ + L A+ GH + +LL S
Sbjct: 169 QDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSS 228
Query: 548 GANIN-QKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+ + N D P+H A GH + +I + R + S P++ A
Sbjct: 229 GADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPL---TNRACDTGLNKVS---PVYSAV 282
Query: 606 KWGYEGIARLLIEHGSEPSLQ 626
G+E +L+ +G P Q
Sbjct: 283 FGGHEDCLEILLRNGYSPDAQ 303
Score = 50.0 bits (114), Expect = 4e-05
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQT---PLHLAAINNKTVVI 817
V+V D+ G+ +H AA + E +LI ++ N K LHLAA ++
Sbjct: 30 VDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIV 89
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++LL+ GA+ NA + TPL A E G I ++LL + ++
Sbjct: 90 QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 132
Score = 41.5 bits (93), Expect = 0.013
Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Query: 526 CSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
CS + A+ + VL LL G +++ + P+H A + + C++ +I A+ S
Sbjct: 5 CSTVGLAAREANVKVLRQLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLIN-ADSSE 63
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPS 624
I + G LHLA+ G+ I ++L+E G++P+
Sbjct: 64 NYIKMK--TFEGFCALHLAASQGHWKIVQILLEAGADPN 100
>AK001283-1|BAA91599.1| 445|Homo sapiens protein ( Homo sapiens
cDNA FLJ10421 fis, clone NT2RP1000202, weakly similar to
ANKYRIN. ).
Length = 445
Score = 74.1 bits (174), Expect = 2e-12
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +LH AS A I++ LL G+ D + L A+ G L +L+ SGAN+
Sbjct: 73 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 132
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + +DK TPL +A GH CV+ ++ SG ++ C +S P+H A++ G+
Sbjct: 133 NCQALDKATPLFIAAQEGHTKCVELLL----SSGADPDLYCNEDSWQLPIHAAAQMGHTK 188
Query: 612 IARLLI 617
I LLI
Sbjct: 189 ILDLLI 194
Score = 63.7 bits (148), Expect = 3e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 7/136 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G ALH+A+ G IV+ LLE G++ NAT L E + L A G +VL +LL GAN+
Sbjct: 6 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFSAVENGQIDVLRLLLQHGANV 65
Query: 552 N-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N ++ LH A + +K ++ + N C ++ G TPL +A+++G
Sbjct: 66 NGSHSMCGWNSLHQASFQENAEIIKLLL------RKGANKECQDDFGITPLFVAAQYGKL 119
Query: 611 GIARLLIEHGSEPSLQ 626
+LI G+ + Q
Sbjct: 120 ESLSILISSGANVNCQ 135
Score = 58.8 bits (136), Expect = 8e-08
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+ +LH A+ E +L+ AN C++ TPL +AA K + +L+ +GAN+
Sbjct: 73 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 132
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLS--YNPDITLLNATEKTALAVAKDKVHLTIIDL 885
N + + TPL A++ G+ ++LLS +PD+ + + + A H I+DL
Sbjct: 133 NCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDL 192
Query: 886 IDNYANKYANT 896
+ N+ +T
Sbjct: 193 LIPLTNRACDT 203
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T L AA+YG E +ILI + ANVNC+ TPL +AA T + LLL +G
Sbjct: 103 DDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 162
Query: 825 A--NINAIDVARNTPLHDASETGNIGAAKILL 854
A ++ + + P+H A++ G+ +L+
Sbjct: 163 ADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 194
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G+T L VA+ +GK + L+ G+ +N L++ + L A+ GH + +LL S
Sbjct: 102 QDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSS 161
Query: 548 GANIN-QKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+ + N D P+H A GH + +I + R + S P++ A
Sbjct: 162 GADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPL---TNRACDTGLNKVS---PVYSAV 215
Query: 606 KWGYEGIARLLIEHGSEPSLQ 626
G+E +L+ +G P Q
Sbjct: 216 FGGHEDCLEILLRNGYSPDAQ 236
Score = 50.8 bits (116), Expect = 2e-05
Identities = 34/88 (38%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
GF ALH AA G + IL+ A+ N + TPL A N + V+RLLL +GAN+
Sbjct: 6 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFSAVENGQIDVLRLLLQHGANV 65
Query: 828 N-AIDVARNTPLHDASETGNIGAAKILL 854
N + + LH AS N K+LL
Sbjct: 66 NGSHSMCGWNSLHQASFQENAEIIKLLL 93
Score = 43.2 bits (97), Expect = 0.004
Identities = 20/56 (35%), Positives = 32/56 (57%)
Query: 805 LHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
LHLAA ++++LL+ GA+ NA + TPL A E G I ++LL + ++
Sbjct: 10 LHLAASQGHWKIVQILLEAGADPNATTLEETTPLFSAVENGQIDVLRLLLQHGANV 65
>AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ10123 fis, clone HEMBA1002939, weakly similar to
ANKYRIN R. ).
Length = 518
Score = 74.1 bits (174), Expect = 2e-12
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +LH AS A I++ LL G+ D + L A+ G L +L+ SGAN+
Sbjct: 146 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 205
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + +DK TPL +A GH CV+ ++ SG ++ C +S P+H A++ G+
Sbjct: 206 NCQALDKATPLFIAAQEGHTKCVELLL----SSGADPDLYCNEDSWQLPIHAAAQMGHTK 261
Query: 612 IARLLI 617
I LLI
Sbjct: 262 ILDLLI 267
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 7/136 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G ALH+A+ G IV+ LLE G++ NAT L E + L A G +VL +LL GAN+
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Query: 552 N-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N ++ LH A + +K ++ + N C ++ G TPL +A+++G
Sbjct: 139 NGSHSMCGWNSLHQASFQENAEIIKLLL------RKGANKECQDDFGITPLFVAAQYGKL 192
Query: 611 GIARLLIEHGSEPSLQ 626
+LI G+ + Q
Sbjct: 193 ESLSILISSGANVNCQ 208
Score = 58.8 bits (136), Expect = 8e-08
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+ +LH A+ E +L+ AN C++ TPL +AA K + +L+ +GAN+
Sbjct: 146 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 205
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLS--YNPDITLLNATEKTALAVAKDKVHLTIIDL 885
N + + TPL A++ G+ ++LLS +PD+ + + + A H I+DL
Sbjct: 206 NCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDL 265
Query: 886 IDNYANKYANT 896
+ N+ +T
Sbjct: 266 LIPLTNRACDT 276
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T L AA+YG E +ILI + ANVNC+ TPL +AA T + LLL +G
Sbjct: 176 DDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235
Query: 825 A--NINAIDVARNTPLHDASETGNIGAAKILL 854
A ++ + + P+H A++ G+ +L+
Sbjct: 236 ADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 741 HPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKK 800
H EC +S ++ + + GF ALH AA G + IL+ A+ N +
Sbjct: 53 HNSVECLQMLINADSSENY-IKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLE 111
Query: 801 AQTPLHLAAINNKTVVIRLLLDNGANIN-AIDVARNTPLHDASETGNIGAAKILL 854
TPL LA N + V+RLLL +GAN+N + + LH AS N K+LL
Sbjct: 112 ETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLL 166
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G+T L VA+ +GK + L+ G+ +N L++ + L A+ GH + +LL S
Sbjct: 175 QDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSS 234
Query: 548 GANIN-QKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+ + N D P+H A GH + +I + R + S P++ A
Sbjct: 235 GADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPL---TNRACDTGLNKVS---PVYSAV 288
Query: 606 KWGYEGIARLLIEHGSEPSLQ 626
G+E +L+ +G P Q
Sbjct: 289 FGGHEDCLEILLRNGYSPDAQ 309
Score = 50.0 bits (114), Expect = 4e-05
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQT---PLHLAAINNKTVVI 817
V+V D+ G+ +H AA + E +LI ++ N K LHLAA ++
Sbjct: 36 VDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIV 95
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++LL+ GA+ NA + TPL A E G I ++LL + ++
Sbjct: 96 QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 526 CSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
CS + A+ G+ VL LL G +++ + P+H A + + C++ +I A+ S
Sbjct: 11 CSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLIN-ADSSE 69
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPS 624
I + G LHLA+ G+ I ++L+E G++P+
Sbjct: 70 NYIKMK--TFEGFCALHLAASQGHWKIVQILLEAGADPN 106
Score = 33.9 bits (74), Expect = 2.6
Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 3/115 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AAR G + L+ +V+ + + P+H AA +N +++L++ ++ N I +
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 835 ---NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LH A+ G+ +ILL D E T L +A + + ++ L+
Sbjct: 77 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLL 131
>AF308285-1|AAG48253.1| 1188|Homo sapiens serologically defined
breast cancer antigen NY-BR-16 protein.
Length = 1188
Score = 74.1 bits (174), Expect = 2e-12
Identities = 93/398 (23%), Positives = 161/398 (40%), Gaps = 20/398 (5%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T L A+ G IV+ LL +++NA +AL YA + G+ +V+ +LL SGA+I
Sbjct: 302 ITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIE 361
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
N + +TPL A + GH+ + ++ +G IN + +NE + L LA G+ +
Sbjct: 362 DHNENGHTPLMEAGSAGHVEVARLLL----ENGAGINTH-SNEFKESALTLACYKGHLEM 416
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYA---HNLRILQVLKSCTPNLFEYIHITSSEVKKISC 669
R L+E G++ + TA A ++ + ++L + S + +C
Sbjct: 417 VRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 476
Query: 670 ESEKPTSLKLQNLTLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI 729
+ L + ND T ++ A G ++ + A I
Sbjct: 477 GGHVELAALLIERGASLEEVNDEGYT--------PLMEAAREGHEEMVALLLG--QGANI 526
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIF 789
E++ L C + ++ + T L AA+ G E L+
Sbjct: 527 NAQTEETQETALTLACCGGFLEVADFLIKAGADI-ELGCSTPLMEAAQEGHLELVKYLLA 585
Query: 790 NRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGA 849
ANV+ T L A N T V +LL GA++ TPL A+ G++
Sbjct: 586 AGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCT 645
Query: 850 AKILLSYNPDITLLNATEKTAL-AVAKDKVHLTIIDLI 886
+ L+S + T L A+A HL +++L+
Sbjct: 646 VQFLISKGAECESEPQLIMTILSALACAGGHLAVVELL 683
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/142 (31%), Positives = 69/142 (48%), Gaps = 7/142 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++ S G TAL A G +V+ LLE G+ I + N + L A S GH V +L
Sbjct: 327 VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLL 386
Query: 545 LHSGANIN-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
L +GA IN N K + L LA GHL V+ ++ K + +T L
Sbjct: 387 LENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHK------TDEMHTALME 440
Query: 604 ASKWGYEGIARLLIEHGSEPSL 625
A G+ +ARLL++ G++ ++
Sbjct: 441 ACMDGHVEVARLLLDSGAQVNM 462
Score = 55.6 bits (128), Expect = 7e-07
Identities = 98/404 (24%), Positives = 161/404 (39%), Gaps = 34/404 (8%)
Query: 504 KATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLH 563
+A T + S NA + S L A S G N + LL G ++N+ + + L
Sbjct: 214 EAAAALTRMRAESTANAGQSDNRS-LAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLC 272
Query: 564 LAVNNGHLHCVKAIIYFAEHSGRKININCANESGN-TPLHLASKWGYEGIARLLIEHGSE 622
LA + G+ + ++ A H+ N+ G+ TPL A+ G+ I +LL+ H ++
Sbjct: 273 LACSAGYYELAQVLL--AMHA----NVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKAD 326
Query: 623 PSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNL 682
+ Q+S TA YA C + + + I +E + ++
Sbjct: 327 VNAQSSTGNTALTYA-----------CAGGYVDVVKVLLESGASIEDHNENGHTPLME-- 373
Query: 683 TLKCSDTNDASKTIENLKLIERILRAISYGDVKLACFYMNIDYSAFI----APDKEKSNS 738
A +EN I + LAC+ +++ F+ A + K++
Sbjct: 374 AGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDE 433
Query: 739 LCHPLCE-CQYCKRKTESC---TDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANV 794
+ L E C + + VN+ + + L AA G E +LI A++
Sbjct: 434 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASL 493
Query: 795 NCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA-IDVARNTPLHDASETGNIGAAKIL 853
N + TPL AA ++ LLL GANINA + + T L A G + A L
Sbjct: 494 EEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFL 553
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIID-LIDNYANKYANT 896
+ DI L T L A + HL ++ L+ AN +A T
Sbjct: 554 IKAGADIEL---GCSTPLMEAAQEGHLELVKYLLAAGANVHATT 594
Score = 55.2 bits (127), Expect = 1e-06
Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 5/131 (3%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T L A+ G +V+ LL G+ ++AT +AL YA GH +V +LL +GA++
Sbjct: 566 TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 625
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
++ TPL A GH+ V+ +I + + S LA G+ +
Sbjct: 626 ESEGGRTPLMKAARAGHVCTVQFLISKGAECESEPQLIMTILSA-----LACAGGHLAVV 680
Query: 614 RLLIEHGSEPS 624
LL+ HG++P+
Sbjct: 681 ELLLAHGADPT 691
Score = 38.3 bits (85), Expect = 0.12
Identities = 32/133 (24%), Positives = 58/133 (43%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ + G TAL YA G + ++L+ A++ ++ +TPL AA ++
Sbjct: 589 NVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQF 648
Query: 820 LLDNGANINAIDVARNTPLHD-ASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
L+ GA + T L A G++ ++LL++ D T T L A
Sbjct: 649 LISKGAECESEPQLIMTILSALACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAPKGG 708
Query: 879 HLTIIDLIDNYAN 891
H ++ + +Y N
Sbjct: 709 HTSVGCYLLDYPN 721
Score = 33.1 bits (72), Expect = 4.5
Identities = 18/53 (33%), Positives = 28/53 (52%)
Query: 521 TDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHC 573
T+ N +AL A + GH+ ++ LL GA+I ++ TPL LA + C
Sbjct: 1079 TESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATSWSCWC 1131
Score = 32.3 bits (70), Expect = 7.9
Identities = 21/52 (40%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 758 DFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAA 809
D D +SN TAL A G +E L+ A++ R+KK TPL LAA
Sbjct: 1074 DIDAQT-ESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAA 1124
>AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein.
Length = 518
Score = 74.1 bits (174), Expect = 2e-12
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +LH AS A I++ LL G+ D + L A+ G L +L+ SGAN+
Sbjct: 146 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 205
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + +DK TPL +A GH CV+ ++ SG ++ C +S P+H A++ G+
Sbjct: 206 NCQALDKATPLFIAAQEGHTKCVELLL----SSGADPDLYCNEDSWQLPIHAAAQMGHTK 261
Query: 612 IARLLI 617
I LLI
Sbjct: 262 ILDLLI 267
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 7/136 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G ALH+A+ G IV+ LLE G++ NAT L E + L A G +VL +LL GAN+
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Query: 552 N-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N ++ LH A + +K ++ + N C ++ G TPL +A+++G
Sbjct: 139 NGSHSMCGWNSLHQASFQENAEIIKLLL------RKGANKECQDDFGITPLFVAAQYGKL 192
Query: 611 GIARLLIEHGSEPSLQ 626
+LI G+ + Q
Sbjct: 193 ESLSILISSGANVNCQ 208
Score = 58.8 bits (136), Expect = 8e-08
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+ +LH A+ E +L+ AN C++ TPL +AA K + +L+ +GAN+
Sbjct: 146 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 205
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLS--YNPDITLLNATEKTALAVAKDKVHLTIIDL 885
N + + TPL A++ G+ ++LLS +PD+ + + + A H I+DL
Sbjct: 206 NCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDL 265
Query: 886 IDNYANKYANT 896
+ N+ +T
Sbjct: 266 LIPLTNRACDT 276
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T L AA+YG E +ILI + ANVNC+ TPL +AA T + LLL +G
Sbjct: 176 DDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235
Query: 825 A--NINAIDVARNTPLHDASETGNIGAAKILL 854
A ++ + + P+H A++ G+ +L+
Sbjct: 236 ADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 741 HPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKK 800
H EC +S ++ + + GF ALH AA G + IL+ A+ N +
Sbjct: 53 HNSVECLQMLINADSSENY-IKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLE 111
Query: 801 AQTPLHLAAINNKTVVIRLLLDNGANIN-AIDVARNTPLHDASETGNIGAAKILL 854
TPL LA N + V+RLLL +GAN+N + + LH AS N K+LL
Sbjct: 112 ETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLL 166
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G+T L VA+ +GK + L+ G+ +N L++ + L A+ GH + +LL S
Sbjct: 175 QDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSS 234
Query: 548 GANIN-QKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+ + N D P+H A GH + +I + R + S P++ A
Sbjct: 235 GADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPL---TNRACDTGLNKVS---PVYSAV 288
Query: 606 KWGYEGIARLLIEHGSEPSLQ 626
G+E +L+ +G P Q
Sbjct: 289 FGGHEDCLEILLRNGYSPDAQ 309
Score = 50.0 bits (114), Expect = 4e-05
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQT---PLHLAAINNKTVVI 817
V+V D+ G+ +H AA + E +LI ++ N K LHLAA ++
Sbjct: 36 VDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIV 95
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++LL+ GA+ NA + TPL A E G I ++LL + ++
Sbjct: 96 QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 526 CSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
CS + A+ G+ VL LL G +++ + P+H A + + C++ +I A+ S
Sbjct: 11 CSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLIN-ADSSE 69
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPS 624
I + G LHLA+ G+ I ++L+E G++P+
Sbjct: 70 NYIKMK--TFEGFCALHLAASQGHWKIVQILLEAGADPN 106
Score = 33.9 bits (74), Expect = 2.6
Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 3/115 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AAR G + L+ +V+ + + P+H AA +N +++L++ ++ N I +
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 835 ---NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LH A+ G+ +ILL D E T L +A + + ++ L+
Sbjct: 77 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLL 131
>AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein.
Length = 326
Score = 74.1 bits (174), Expect = 2e-12
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +LH AS A I++ LL G+ D + L A+ G L +L+ SGAN+
Sbjct: 146 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 205
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + +DK TPL +A GH CV+ ++ SG ++ C +S P+H A++ G+
Sbjct: 206 NCQALDKATPLFIAAQEGHTKCVELLL----SSGADPDLYCNEDSWQLPIHAAAQMGHTK 261
Query: 612 IARLLI 617
I LLI
Sbjct: 262 ILDLLI 267
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 7/136 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G ALH+A+ G IV+ LLE G++ NAT L E + L A G +VL +LL GAN+
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Query: 552 N-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N ++ LH A + +K ++ + N C ++ G TPL +A+++G
Sbjct: 139 NGSHSMCGWNSLHQASFQENAEIIKLLL------RKGANKECQDDFGITPLFVAAQYGKL 192
Query: 611 GIARLLIEHGSEPSLQ 626
+LI G+ + Q
Sbjct: 193 ESLSILISSGANVNCQ 208
Score = 58.8 bits (136), Expect = 8e-08
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+ +LH A+ E +L+ AN C++ TPL +AA K + +L+ +GAN+
Sbjct: 146 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 205
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLS--YNPDITLLNATEKTALAVAKDKVHLTIIDL 885
N + + TPL A++ G+ ++LLS +PD+ + + + A H I+DL
Sbjct: 206 NCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDL 265
Query: 886 IDNYANKYANT 896
+ N+ +T
Sbjct: 266 LIPLTNRACDT 276
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T L AA+YG E +ILI + ANVNC+ TPL +AA T + LLL +G
Sbjct: 176 DDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235
Query: 825 A--NINAIDVARNTPLHDASETGNIGAAKILL 854
A ++ + + P+H A++ G+ +L+
Sbjct: 236 ADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 741 HPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKK 800
H EC +S ++ + + GF ALH AA G + IL+ A+ N +
Sbjct: 53 HNSVECLQMLINADSSENY-IKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLE 111
Query: 801 AQTPLHLAAINNKTVVIRLLLDNGANIN-AIDVARNTPLHDASETGNIGAAKILL 854
TPL LA N + V+RLLL +GAN+N + + LH AS N K+LL
Sbjct: 112 ETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLL 166
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G+T L VA+ +GK + L+ G+ +N L++ + L A+ GH + +LL S
Sbjct: 175 QDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSS 234
Query: 548 GANIN-QKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+ + N D P+H A GH + +I + R + S P++ A
Sbjct: 235 GADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPL---TNRACDTGLNKVS---PVYSAV 288
Query: 606 KWGYEGIARLLIEHGSEPSLQ 626
G+E +L+ +G P Q
Sbjct: 289 FGGHEDCLEILLRNGYSPDAQ 309
Score = 50.0 bits (114), Expect = 4e-05
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQT---PLHLAAINNKTVVI 817
V+V D+ G+ +H AA + E +LI ++ N K LHLAA ++
Sbjct: 36 VDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIV 95
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++LL+ GA+ NA + TPL A E G I ++LL + ++
Sbjct: 96 QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 526 CSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
CS + A+ G+ VL LL G +++ + P+H A + + C++ +I A+ S
Sbjct: 11 CSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLIN-ADSSE 69
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPS 624
I + G LHLA+ G+ I ++L+E G++P+
Sbjct: 70 NYIKMK--TFEGFCALHLAASQGHWKIVQILLEAGADPN 106
Score = 33.9 bits (74), Expect = 2.6
Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 3/115 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AAR G + L+ +V+ + + P+H AA +N +++L++ ++ N I +
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 835 ---NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LH A+ G+ +ILL D E T L +A + + ++ L+
Sbjct: 77 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLL 131
>AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 340
Score = 74.1 bits (174), Expect = 2e-12
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +LH AS A I++ LL G+ D + L A+ G L +L+ SGAN+
Sbjct: 156 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 215
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N + +DK TPL +A GH CV+ ++ SG ++ C +S P+H A++ G+
Sbjct: 216 NCQALDKATPLFIAAQEGHTKCVELLL----SSGADPDLYCNEDSWQLPIHAAAQMGHTK 271
Query: 612 IARLLI 617
I LLI
Sbjct: 272 ILDLLI 277
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 7/136 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G ALH+A+ G IV+ LLE G++ NAT L E + L A G +VL +LL GAN+
Sbjct: 89 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 148
Query: 552 N-QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
N ++ LH A + +K ++ + N C ++ G TPL +A+++G
Sbjct: 149 NGSHSMCGWNSLHQASFQENAEIIKLLL------RKGANKECQDDFGITPLFVAAQYGKL 202
Query: 611 GIARLLIEHGSEPSLQ 626
+LI G+ + Q
Sbjct: 203 ESLSILISSGANVNCQ 218
Score = 58.8 bits (136), Expect = 8e-08
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G+ +LH A+ E +L+ AN C++ TPL +AA K + +L+ +GAN+
Sbjct: 156 GWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANV 215
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLS--YNPDITLLNATEKTALAVAKDKVHLTIIDL 885
N + + TPL A++ G+ ++LLS +PD+ + + + A H I+DL
Sbjct: 216 NCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDL 275
Query: 886 IDNYANKYANT 896
+ N+ +T
Sbjct: 276 LIPLTNRACDT 286
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D G T L AA+YG E +ILI + ANVNC+ TPL +AA T + LLL +G
Sbjct: 186 DDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 245
Query: 825 A--NINAIDVARNTPLHDASETGNIGAAKILL 854
A ++ + + P+H A++ G+ +L+
Sbjct: 246 ADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 277
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 741 HPLCECQYCKRKTESCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKK 800
H EC +S ++ + + GF ALH AA G + IL+ A+ N +
Sbjct: 63 HNSVECLQMLINADSSENY-IKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLE 121
Query: 801 AQTPLHLAAINNKTVVIRLLLDNGANIN-AIDVARNTPLHDASETGNIGAAKILL 854
TPL LA N + V+RLLL +GAN+N + + LH AS N K+LL
Sbjct: 122 ETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLL 176
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G+T L VA+ +GK + L+ G+ +N L++ + L A+ GH + +LL S
Sbjct: 185 QDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSS 244
Query: 548 GANIN-QKNIDK-NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA+ + N D P+H A GH + +I + R + S P++ A
Sbjct: 245 GADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPL---TNRACDTGLNKVS---PVYSAV 298
Query: 606 KWGYEGIARLLIEHGSEPSLQ 626
G+E +L+ +G P Q
Sbjct: 299 FGGHEDCLEILLRNGYSPDAQ 319
Score = 50.0 bits (114), Expect = 4e-05
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQT---PLHLAAINNKTVVI 817
V+V D+ G+ +H AA + E +LI ++ N K LHLAA ++
Sbjct: 46 VDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIV 105
Query: 818 RLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
++LL+ GA+ NA + TPL A E G I ++LL + ++
Sbjct: 106 QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 148
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 526 CSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSG 585
CS + A+ G+ VL LL G +++ + P+H A + + C++ +I A+ S
Sbjct: 21 CSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLIN-ADSSE 79
Query: 586 RKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPS 624
I + G LHLA+ G+ I ++L+E G++P+
Sbjct: 80 NYIKMK--TFEGFCALHLAASQGHWKIVQILLEAGADPN 116
Score = 33.9 bits (74), Expect = 2.6
Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 3/115 (2%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AAR G + L+ +V+ + + P+H AA +N +++L++ ++ N I +
Sbjct: 27 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 86
Query: 835 ---NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
LH A+ G+ +ILL D E T L +A + + ++ L+
Sbjct: 87 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLL 141
>BC070234-1|AAH70234.1| 371|Homo sapiens ANKRD12 protein protein.
Length = 371
Score = 73.7 bits (173), Expect = 3e-12
Identities = 38/120 (31%), Positives = 67/120 (55%), Gaps = 6/120 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ R+ G T LH+A+I G V+ L+ +G+ +N D + LH A + G+ +V +L
Sbjct: 155 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 214
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +GA++N + +D +TPLH + ++GH VK ++ H G AN+ G P+ +A
Sbjct: 215 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLL---RHGGNPFQ---ANKHGERPVDVA 268
Score = 66.9 bits (156), Expect = 3e-10
Identities = 34/93 (36%), Positives = 50/93 (53%)
Query: 794 VNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
VN RN++ +TPLH+AAI ++ L+ GAN+N D A TPLH+A G AKIL
Sbjct: 155 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 214
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
++ D+ + T L + H I+ L+
Sbjct: 215 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLL 247
Score = 60.9 bits (141), Expect = 2e-08
Identities = 39/123 (31%), Positives = 60/123 (48%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ RG + L+ GAN+N K+ TPLH A N G+ K +I +G +
Sbjct: 166 LHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIA----AGADV 221
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
N ++ +TPLH ++ G+ I +LL+ HG P N + + D A + +LK
Sbjct: 222 NTQGLDD--DTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKR 279
Query: 649 CTP 651
P
Sbjct: 280 EVP 282
Score = 54.0 bits (124), Expect = 2e-06
Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 4/130 (3%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFD---VNVCDSNGFTALHYAARYGLDEFCNI 786
A D ++ HP + ++KT S + VN + G T LH AA G +
Sbjct: 122 ARDNSPDSTPNHP-SQTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVKQVKE 180
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
LI ANVN ++ TPLH A V ++L+ GA++N + +TPLHD++ +G+
Sbjct: 181 LISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGH 240
Query: 847 IGAAKILLSY 856
K+LL +
Sbjct: 241 RDIVKLLLRH 250
Score = 47.2 bits (107), Expect = 3e-04
Identities = 26/67 (38%), Positives = 37/67 (55%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VNV D G+T LH A G + ILI A+VN + TPLH +A + +++L
Sbjct: 187 NVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKL 246
Query: 820 LLDNGAN 826
LL +G N
Sbjct: 247 LLRHGGN 253
>AY533564-1|AAS45545.2| 2039|Homo sapiens ankyrin repeat-containing
cofactor-2 protein.
Length = 2039
Score = 73.7 bits (173), Expect = 3e-12
Identities = 38/120 (31%), Positives = 67/120 (55%), Gaps = 6/120 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ R+ G T LH+A+I G V+ L+ +G+ +N D + LH A + G+ +V +L
Sbjct: 155 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 214
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +GA++N + +D +TPLH + ++GH VK ++ H G AN+ G P+ +A
Sbjct: 215 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLL---RHGGNPFQ---ANKHGERPVDVA 268
Score = 66.9 bits (156), Expect = 3e-10
Identities = 34/93 (36%), Positives = 50/93 (53%)
Query: 794 VNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
VN RN++ +TPLH+AAI ++ L+ GAN+N D A TPLH+A G AKIL
Sbjct: 155 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 214
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
++ D+ + T L + H I+ L+
Sbjct: 215 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLL 247
Score = 60.9 bits (141), Expect = 2e-08
Identities = 39/123 (31%), Positives = 60/123 (48%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ RG + L+ GAN+N K+ TPLH A N G+ K +I +G +
Sbjct: 166 LHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIA----AGADV 221
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
N ++ +TPLH ++ G+ I +LL+ HG P N + + D A + +LK
Sbjct: 222 NTQGLDD--DTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKR 279
Query: 649 CTP 651
P
Sbjct: 280 EVP 282
Score = 54.0 bits (124), Expect = 2e-06
Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 4/130 (3%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFD---VNVCDSNGFTALHYAARYGLDEFCNI 786
A D ++ HP + ++KT S + VN + G T LH AA G +
Sbjct: 122 ARDNSPDSTPNHP-SQTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVKQVKE 180
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
LI ANVN ++ TPLH A V ++L+ GA++N + +TPLHD++ +G+
Sbjct: 181 LISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGH 240
Query: 847 IGAAKILLSY 856
K+LL +
Sbjct: 241 RDIVKLLLRH 250
Score = 47.2 bits (107), Expect = 3e-04
Identities = 26/67 (38%), Positives = 37/67 (55%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VNV D G+T LH A G + ILI A+VN + TPLH +A + +++L
Sbjct: 187 NVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKL 246
Query: 820 LLDNGAN 826
LL +G N
Sbjct: 247 LLRHGGN 253
>AY373757-1|AAR25662.1| 2062|Homo sapiens ankyrin repeat-containing
protein protein.
Length = 2062
Score = 73.7 bits (173), Expect = 3e-12
Identities = 38/120 (31%), Positives = 67/120 (55%), Gaps = 6/120 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ R+ G T LH+A+I G V+ L+ +G+ +N D + LH A + G+ +V +L
Sbjct: 178 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 237
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +GA++N + +D +TPLH + ++GH VK ++ H G AN+ G P+ +A
Sbjct: 238 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLL---RHGGNPFQ---ANKHGERPVDVA 291
Score = 66.9 bits (156), Expect = 3e-10
Identities = 34/93 (36%), Positives = 50/93 (53%)
Query: 794 VNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
VN RN++ +TPLH+AAI ++ L+ GAN+N D A TPLH+A G AKIL
Sbjct: 178 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 237
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
++ D+ + T L + H I+ L+
Sbjct: 238 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLL 270
Score = 60.9 bits (141), Expect = 2e-08
Identities = 39/123 (31%), Positives = 60/123 (48%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ RG + L+ GAN+N K+ TPLH A N G+ K +I +G +
Sbjct: 189 LHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIA----AGADV 244
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
N ++ +TPLH ++ G+ I +LL+ HG P N + + D A + +LK
Sbjct: 245 NTQGLDD--DTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKR 302
Query: 649 CTP 651
P
Sbjct: 303 EVP 305
Score = 55.6 bits (128), Expect = 7e-07
Identities = 42/130 (32%), Positives = 64/130 (49%), Gaps = 4/130 (3%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFD---VNVCDSNGFTALHYAARYGLDEFCNI 786
A D ++ HP + ++KT S T VN + G T LH AA G +
Sbjct: 145 ARDNSPDSTPNHP-SQTTPAQKKTPSSTSRQKDKVNKRNERGETPLHMAAIRGDVKQVKE 203
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
LI ANVN ++ TPLH A V ++L+ GA++N + +TPLHD++ +G+
Sbjct: 204 LISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGH 263
Query: 847 IGAAKILLSY 856
K+LL +
Sbjct: 264 RDIVKLLLRH 273
Score = 47.2 bits (107), Expect = 3e-04
Identities = 26/67 (38%), Positives = 37/67 (55%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VNV D G+T LH A G + ILI A+VN + TPLH +A + +++L
Sbjct: 210 NVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKL 269
Query: 820 LLDNGAN 826
LL +G N
Sbjct: 270 LLRHGGN 276
>AK024808-1|BAB15014.1| 492|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21155 fis, clone CAS09757. ).
Length = 492
Score = 73.7 bits (173), Expect = 3e-12
Identities = 38/120 (31%), Positives = 67/120 (55%), Gaps = 6/120 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ R+ G T LH+A+I G V+ L+ +G+ +N D + LH A + G+ +V +L
Sbjct: 178 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 237
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +GA++N + +D +TPLH + ++GH VK ++ H G AN+ G P+ +A
Sbjct: 238 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLL---RHGGNPFQ---ANKHGERPVDVA 291
Score = 66.9 bits (156), Expect = 3e-10
Identities = 34/93 (36%), Positives = 50/93 (53%)
Query: 794 VNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
VN RN++ +TPLH+AAI ++ L+ GAN+N D A TPLH+A G AKIL
Sbjct: 178 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 237
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
++ D+ + T L + H I+ L+
Sbjct: 238 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLL 270
Score = 60.9 bits (141), Expect = 2e-08
Identities = 39/123 (31%), Positives = 60/123 (48%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ RG + L+ GAN+N K+ TPLH A N G+ K +I +G +
Sbjct: 189 LHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIA----AGADV 244
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
N ++ +TPLH ++ G+ I +LL+ HG P N + + D A + +LK
Sbjct: 245 NTQGLDD--DTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKR 302
Query: 649 CTP 651
P
Sbjct: 303 EVP 305
Score = 55.6 bits (128), Expect = 7e-07
Identities = 42/130 (32%), Positives = 64/130 (49%), Gaps = 4/130 (3%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFD---VNVCDSNGFTALHYAARYGLDEFCNI 786
A D ++ HP + ++KT S T VN + G T LH AA G +
Sbjct: 145 ARDNSPDSTPNHP-SQTTPAQKKTPSSTSRQKDKVNKRNERGETPLHMAAIRGDVKQVKE 203
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
LI ANVN ++ TPLH A V ++L+ GA++N + +TPLHD++ +G+
Sbjct: 204 LISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGH 263
Query: 847 IGAAKILLSY 856
K+LL +
Sbjct: 264 RDIVKLLLRH 273
Score = 47.2 bits (107), Expect = 3e-04
Identities = 26/67 (38%), Positives = 37/67 (55%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VNV D G+T LH A G + ILI A+VN + TPLH +A + +++L
Sbjct: 210 NVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKL 269
Query: 820 LLDNGAN 826
LL +G N
Sbjct: 270 LLRHGGN 276
>AF317425-1|AAG38609.1| 2062|Homo sapiens GAC-1 protein.
Length = 2062
Score = 73.7 bits (173), Expect = 3e-12
Identities = 38/120 (31%), Positives = 67/120 (55%), Gaps = 6/120 (5%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ R+ G T LH+A+I G V+ L+ +G+ +N D + LH A + G+ +V +L
Sbjct: 178 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 237
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA 604
+ +GA++N + +D +TPLH + ++GH VK ++ H G AN+ G P+ +A
Sbjct: 238 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLL---RHGGNPFQ---ANKHGERPVDVA 291
Score = 66.9 bits (156), Expect = 3e-10
Identities = 34/93 (36%), Positives = 50/93 (53%)
Query: 794 VNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKIL 853
VN RN++ +TPLH+AAI ++ L+ GAN+N D A TPLH+A G AKIL
Sbjct: 178 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 237
Query: 854 LSYNPDITLLNATEKTALAVAKDKVHLTIIDLI 886
++ D+ + T L + H I+ L+
Sbjct: 238 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLL 270
Score = 60.9 bits (141), Expect = 2e-08
Identities = 39/123 (31%), Positives = 60/123 (48%), Gaps = 6/123 (4%)
Query: 529 LHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKI 588
LH A+ RG + L+ GAN+N K+ TPLH A N G+ K +I +G +
Sbjct: 189 LHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIA----AGADV 244
Query: 589 NINCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKS 648
N ++ +TPLH ++ G+ I +LL+ HG P N + + D A + +LK
Sbjct: 245 NTQGLDD--DTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKR 302
Query: 649 CTP 651
P
Sbjct: 303 EVP 305
Score = 54.0 bits (124), Expect = 2e-06
Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 4/130 (3%)
Query: 730 APDKEKSNSLCHPLCECQYCKRKTESCTDFD---VNVCDSNGFTALHYAARYGLDEFCNI 786
A D ++ HP + ++KT S + VN + G T LH AA G +
Sbjct: 145 ARDNSPDSTPNHP-SQTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVKQVKE 203
Query: 787 LIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGN 846
LI ANVN ++ TPLH A V ++L+ GA++N + +TPLHD++ +G+
Sbjct: 204 LISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGH 263
Query: 847 IGAAKILLSY 856
K+LL +
Sbjct: 264 RDIVKLLLRH 273
Score = 47.2 bits (107), Expect = 3e-04
Identities = 26/67 (38%), Positives = 37/67 (55%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VNV D G+T LH A G + ILI A+VN + TPLH +A + +++L
Sbjct: 210 NVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKL 269
Query: 820 LLDNGAN 826
LL +G N
Sbjct: 270 LLRHGGN 276
>DQ388145-2|ABD72216.1| 1482|Homo sapiens CTTNBP2 protein.
Length = 1482
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388144-2|ABD72214.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388143-2|ABD72212.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388142-2|ABD72210.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388141-2|ABD72208.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388140-2|ABD72206.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388139-2|ABD72204.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388138-2|ABD72202.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388137-2|ABD72200.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388136-2|ABD72198.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388135-2|ABD72196.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388134-2|ABD72194.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388133-2|ABD72192.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388132-2|ABD72190.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388131-2|ABD72188.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388130-2|ABD72186.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388129-2|ABD72184.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ388128-2|ABD72182.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ356264-2|ABC87066.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ356263-2|ABC87064.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ356262-2|ABC87062.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ356261-2|ABC87060.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ356260-2|ABC87058.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ356259-2|ABC87056.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ356258-2|ABC87054.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ356257-2|ABC87052.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ354391-2|ABC79055.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ354390-2|ABC79053.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ354389-2|ABC79051.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>DQ354388-2|ABC79049.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>BC106000-1|AAI06001.1| 1663|Homo sapiens cortactin binding protein
2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>AK092230-1|BAC03833.1| 448|Homo sapiens ITOCHONDRIAL PRECURSOR.
protein.
Length = 448
Score = 73.3 bits (172), Expect = 3e-12
Identities = 37/128 (28%), Positives = 69/128 (53%)
Query: 768 GFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANI 827
G + LH AA+YG +L+ + + R K +TPLH+AA + ++ LL+ NGA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 828 NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLID 887
NA D+ + T LH A+E + ++L+ Y D+ + +K+A ++ +K + I+ ++
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDISLEKNNAEILVILQ 157
Query: 888 NYANKYAN 895
N
Sbjct: 158 EAMQNQVN 165
Score = 65.7 bits (153), Expect = 7e-10
Identities = 44/153 (28%), Positives = 78/153 (50%), Gaps = 10/153 (6%)
Query: 503 GKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPL 562
G+ V TL+ G+ TD S LH A+ GH + +LL +G + + + TPL
Sbjct: 17 GQDDEVRTLMANGAPFT-TDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPL 75
Query: 563 HLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSE 622
H+A +GH H V+ ++ +G ++N + T LH A++ + + LLI++G++
Sbjct: 76 HMAAADGHAHIVELLV----RNG--ADVNAKDMLKMTALHWATERHHRDVVELLIKYGAD 129
Query: 623 PSLQNSYHKTAFDYA---HNLRILQVLKSCTPN 652
+ + K+AFD + +N IL +L+ N
Sbjct: 130 VHAFSKFDKSAFDISLEKNNAEILVILQEAMQN 162
Score = 58.0 bits (134), Expect = 1e-07
Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 7/100 (7%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A+ G A IVE L+ G+++NA D+ + +ALH+A+ R H++V+ +L+ GA+++
Sbjct: 73 TPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVVELLIKYGADVHA 132
Query: 554 -KNIDKNT-PLHLAVNNGHLHCVKAIIYFAEHSGRKININ 591
DK+ + L NN + ++ E ++N+N
Sbjct: 133 FSKFDKSAFDISLEKNNAEI-----LVILQEAMQNQVNVN 167
Score = 56.0 bits (129), Expect = 6e-07
Identities = 28/89 (31%), Positives = 51/89 (57%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G + LH+A+ +G + E LL G +A + + LH A++ GH +++ +L+ +GA++
Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADV 97
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYF 580
N K++ K T LH A H V+ +I +
Sbjct: 98 NAKDMLKMTALHWATERHHRDVVELLIKY 126
Score = 33.5 bits (73), Expect = 3.4
Identities = 18/78 (23%), Positives = 41/78 (52%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++D +TALH A+ +VE L++ G++++A + SA + + + +L++L
Sbjct: 97 VNAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDISLEKNNAEILVIL 156
Query: 545 LHSGANINQKNIDKNTPL 562
+ N N ++ P+
Sbjct: 157 QEAMQNQVNVNPERANPV 174
>AF377960-1|AAL32176.1| 1663|Homo sapiens cortactin-binding protein
2 protein.
Length = 1663
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 825
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 826 IKLLLEAGTNRSVKTT 841
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 744 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 803
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 804 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 857
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 858 SLKLLMYH-RIPAHGNSFNE 876
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 736 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 795
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 855
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 856 VDSLKLL 862
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 770 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 830 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 864
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 810 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 869
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 870 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 925
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 926 KNCLEILCRHGGLEPERRDKCNRTVHDVA 954
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 718 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 777
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 778 FTPLCAAAAQGHFECVELLISY 799
>AB051545-1|BAB21849.1| 1662|Homo sapiens KIAA1758 protein protein.
Length = 1662
Score = 73.3 bits (172), Expect = 3e-12
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 494 TALHVASIHGKATIVETLL-EMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
T L A+ G T++ LL E G +IN + + SAL+ A+ GH + + +LL + A +N
Sbjct: 711 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 770
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + TPL A GH CV+ +I + NIN A + G TPL+LA K G +
Sbjct: 771 AADKNGFTPLCAAAAQGHFECVELLISY------DANINHAADGGQTPLYLACKNGNKEC 824
Query: 613 ARLLIEHGSEPSLQNS 628
+LL+E G+ S++ +
Sbjct: 825 IKLLLEAGTNRSVKTT 840
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/94 (41%), Positives = 51/94 (54%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN D NGFT L AA G E +LI AN+N QTPL+LA N I+LL
Sbjct: 769 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 828
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILL 854
L+ G N + TP+H A +TGN+ + K+L+
Sbjct: 829 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 862
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G +AL+ A+ +G V LL +++NA D N + L A+++GH + +L+ ANI
Sbjct: 743 GHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANI 802
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPL+LA NG+ C+K ++ +G N + G TP+H A G
Sbjct: 803 NHAADGGQTPLYLACKNGNKECIKLLL----EAG--TNRSVKTTDGWTPVHAAVDTGNVD 856
Query: 612 IARLLIEHGSEPSLQNSYHK 631
+LL+ H P+ NS+++
Sbjct: 857 SLKLLMYH-RIPAHGNSFNE 875
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/127 (29%), Positives = 59/127 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D+N +G +AL+ AA+ G + +L+ A VN +K TPL AA + L
Sbjct: 735 DINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVEL 794
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
L+ ANIN TPL+ A + GN K+LL + ++ T + A D +
Sbjct: 795 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGN 854
Query: 880 LTIIDLI 886
+ + L+
Sbjct: 855 VDSLKLL 861
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/95 (29%), Positives = 49/95 (51%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + D +G T L A+ G VE L+ + IN + L+ A G++ + +L
Sbjct: 769 VNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 828
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIY 579
L +G N + K D TP+H AV+ G++ +K ++Y
Sbjct: 829 LEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMY 863
Score = 39.9 bits (89), Expect = 0.039
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--A 549
G T L++A +G ++ LLE G+ + + + +H A G+ + L +L++ A
Sbjct: 809 GQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPA 868
Query: 550 NINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGY 609
+ N N +++ ++ G ++ ++ IN AN G T H+A+ G+
Sbjct: 869 HGNSFNEEESESSVFDLDGGE----ESPEGISKPVVPADLINHANREGWTAAHIAASKGF 924
Query: 610 EGIARLLIEHGS-EPSLQNSYHKTAFDYA 637
+ +L HG EP ++ ++T D A
Sbjct: 925 KNCLEILCRHGGLEPERRDKCNRTVHDVA 953
Score = 35.9 bits (79), Expect = 0.64
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 808 AAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE 867
AA N T++ LL + G +IN ++ L+ A++ G+ ++LLS + +
Sbjct: 717 AAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNG 776
Query: 868 KTALAVAKDKVHLTIIDLIDNY 889
T L A + H ++L+ +Y
Sbjct: 777 FTPLCAAAAQGHFECVELLISY 798
>AF451977-1|AAL49758.1| 1431|Homo sapiens cask-interacting protein 1
protein.
Length = 1431
Score = 72.9 bits (171), Expect = 5e-12
Identities = 39/130 (30%), Positives = 72/130 (55%), Gaps = 6/130 (4%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D G +ALH A+++G ++ LLE + ++ D LHYA+ +G + + ++L +
Sbjct: 45 QDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKA 104
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
G+ +N + + + PLHLA +GH + ++ +H N + SG TPL LA ++
Sbjct: 105 GSAVNIPSDEGHIPLHLAAQHGHYDVSEMLL---QHQS---NPCMVDNSGKTPLDLACEF 158
Query: 608 GYEGIARLLI 617
G G+ +LL+
Sbjct: 159 GRVGVVQLLL 168
Score = 68.9 bits (161), Expect = 7e-11
Identities = 38/132 (28%), Positives = 74/132 (56%)
Query: 755 SCTDFDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKT 814
S +VN D +GF+ALH+AA G E ++L+ +A V+ ++ K PLH AA +
Sbjct: 36 STKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRK 95
Query: 815 VVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
++L+L G+ +N + PLH A++ G+ +++LL + + +++ + KT L +A
Sbjct: 96 EPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLA 155
Query: 875 KDKVHLTIIDLI 886
+ + ++ L+
Sbjct: 156 CEFGRVGVVQLL 167
Score = 64.9 bits (151), Expect = 1e-09
Identities = 39/135 (28%), Positives = 75/135 (55%), Gaps = 8/135 (5%)
Query: 503 GKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPL 562
GKA ++ + ++ +N D + SALH+A+ G+ ++ +LL + A ++ K+ PL
Sbjct: 29 GKAKLLGSTKKIN--VNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPL 86
Query: 563 HLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSE 622
H A G +K ++ +G +NI ++ G+ PLHLA++ G+ ++ +L++H S
Sbjct: 87 HYAAWQGRKEPMKLVL----KAGSAVNI--PSDEGHIPLHLAAQHGHYDVSEMLLQHQSN 140
Query: 623 PSLQNSYHKTAFDYA 637
P + ++ KT D A
Sbjct: 141 PCMVDNSGKTPLDLA 155
Score = 64.9 bits (151), Expect = 1e-09
Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 15/197 (7%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG--- 548
G LH+A+ HG + E LL+ S D + + L A G V+ +LL S
Sbjct: 115 GHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCA 174
Query: 549 ANINQKNIDKN-----TPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
A + + D +PLHLA NGH+ ++ ++ +G I+IN +SG T LH
Sbjct: 175 ALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLL----QAG--IDINRQTKSG-TALHE 227
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCTPNLFEYIHITSSE 663
A+ G + RLL++ G ++N+Y +TA D H Q + L E
Sbjct: 228 AALCGKTEVVRLLLDSGINAHVRNTYSQTALDIVHQFTTSQASREIKQLLREASAALQVR 287
Query: 664 VKKISCESEKPTSLKLQ 680
K C + TSL ++
Sbjct: 288 ATKDYCNNYDLTSLNVK 304
Score = 59.7 bits (138), Expect = 5e-08
Identities = 36/103 (34%), Positives = 54/103 (52%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
V++ D+ G LHYAA G E +++ + VN + + PLHLAA + V +L
Sbjct: 75 VDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEML 134
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLL 863
L + +N +D + TPL A E G +G ++LLS N LL
Sbjct: 135 LQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALL 177
Score = 50.4 bits (115), Expect = 3e-05
Identities = 29/74 (39%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D NG + LH AA+ G + +L+ ++N R K+ T LH AA+ KT V+RLLLD+G
Sbjct: 186 DPNGTSPLHLAAKNGHIDIIRLLLQAGIDIN-RQTKSGTALHEAALCGKTEVVRLLLDSG 244
Query: 825 ANINAIDVARNTPL 838
N + + T L
Sbjct: 245 INAHVRNTYSQTAL 258
Score = 45.2 bits (102), Expect = 0.001
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D +G + LH+A+ +G I+ LL+ G +IN +ALH A+ G V+ +LL SG
Sbjct: 186 DPNGTSPLHLAAKNGHIDIIRLLLQAGIDIN-RQTKSGTALHEAALCGKTEVVRLLLDSG 244
Query: 549 ANINQKNIDKNTPLHL 564
N + +N T L +
Sbjct: 245 INAHVRNTYSQTALDI 260
Score = 44.0 bits (99), Expect = 0.002
Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN+ G LH AA++G + +L+ +++N + +TPL LA + V++LL
Sbjct: 108 VNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLL 167
Query: 821 LDNGANI--------NAIDVARNTPLHDASETGNIGAAKILLSYNPDI 860
L + +A D +PLH A++ G+I ++LL DI
Sbjct: 168 LSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDI 215
Score = 44.0 bits (99), Expect = 0.002
Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 803 TPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITL 862
+PLHLAA N +IRLLL G +IN T LH+A+ G ++LL + +
Sbjct: 191 SPLHLAAKNGHIDIIRLLLQAGIDINR-QTKSGTALHEAALCGKTEVVRLLLDSGINAHV 249
Query: 863 LNATEKTALAV 873
N +TAL +
Sbjct: 250 RNTYSQTALDI 260
>AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein
protein.
Length = 520
Score = 72.5 bits (170), Expect = 6e-12
Identities = 45/142 (31%), Positives = 75/142 (52%), Gaps = 5/142 (3%)
Query: 754 ESCTDFDVN--VCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAIN 811
+S D N D++G+TALH+A Y E C L+ + A +PLH A IN
Sbjct: 207 QSAASMDANPATADNHGYTALHWAC-YNGHETCVELLLEQEVFQKTEGNAFSPLHCAVIN 265
Query: 812 NKTVVIRLLLDN-GANI-NAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKT 869
+ +L+D GA+I NA D TPLH A+ T ++ ++LLS+N + +++T KT
Sbjct: 266 DNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKT 325
Query: 870 ALAVAKDKVHLTIIDLIDNYAN 891
L +A + ++++ + A+
Sbjct: 326 PLMMAAENGQTNTVEMLVSSAS 347
Score = 66.1 bits (154), Expect = 5e-10
Identities = 41/138 (29%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ + DS G T LH A+ ++ LL +++N+ D + L A+ G N + ML
Sbjct: 283 VNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEML 342
Query: 545 LHS-GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
+ S A + ++ KNT LHLA + GH A++ + + R + IN N + TPLH+
Sbjct: 343 VSSASAELTLQDNSKNTALHLACSKGHE--TSALLILEKITDRNL-INATNAALQTPLHV 399
Query: 604 ASKWGYEGIARLLIEHGS 621
A++ G + + L+ G+
Sbjct: 400 AARNGLTMVVQELLGKGA 417
Score = 65.7 bits (153), Expect = 7e-10
Identities = 39/142 (27%), Positives = 76/142 (53%), Gaps = 4/142 (2%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
++ LH+A+ HG +E L++ +++ + + + L A+ +GH + +L++ GA+I
Sbjct: 18 ISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 77
Query: 553 QKN-IDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
K+ I K TP+H A NGH C++ +I AE ++ + +G TPL L+ G+
Sbjct: 78 VKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTD 134
Query: 612 IARLLIEHGSEPSLQNSYHKTA 633
L+ G+ ++ + +TA
Sbjct: 135 CVYSLLNKGANVDAKDKWGRTA 156
Score = 64.9 bits (151), Expect = 1e-09
Identities = 41/125 (32%), Positives = 66/125 (52%), Gaps = 3/125 (2%)
Query: 765 DSNGFTALHYAARYGLDEFCNILI--FNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLD 822
+ N F+ LH A + +LI + VN + K +TPLH AA + ++LLL
Sbjct: 252 EGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLS 311
Query: 823 NGANINAIDVARNTPLHDASETGNIGAAKILL-SYNPDITLLNATEKTALAVAKDKVHLT 881
+ A +N++D TPL A+E G ++L+ S + ++TL + ++ TAL +A K H T
Sbjct: 312 HNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHET 371
Query: 882 IIDLI 886
LI
Sbjct: 372 SALLI 376
Score = 63.3 bits (147), Expect = 4e-09
Identities = 40/131 (30%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHS 547
+D +G T L ++ ++G V +LL G+ ++A D +ALH + GH+ + LL
Sbjct: 116 QDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQH 175
Query: 548 GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKW 607
GA ++ TP+HL+ GH+ + A++ A + N A+ G T LH A
Sbjct: 176 GAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSA--ASMDANPATADNHGYTALHWACYN 233
Query: 608 GYEGIARLLIE 618
G+E LL+E
Sbjct: 234 GHETCVELLLE 244
Score = 63.3 bits (147), Expect = 4e-09
Identities = 43/142 (30%), Positives = 70/142 (49%), Gaps = 7/142 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLE-MGSEI-NATDLNECSALHYASSRGHQNVLLMLLH 546
+ + + LH A I+ E L++ +G+ I NATD + LH A+ H L +LL
Sbjct: 252 EGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLS 311
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
A +N + TPL +A NG + V+ ++ S + + S NT LHLA
Sbjct: 312 HNAQVNSVDSTGKTPLMMAAENGQTNTVEMLV-----SSASAELTLQDNSKNTALHLACS 366
Query: 607 WGYEGIARLLIEHGSEPSLQNS 628
G+E A L++E ++ +L N+
Sbjct: 367 KGHETSALLILEKITDRNLINA 388
Score = 61.3 bits (142), Expect = 1e-08
Identities = 45/139 (32%), Positives = 73/139 (52%), Gaps = 5/139 (3%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN DS G T LH AA E +L+ + A VN + +TPL +AA N +T + +L
Sbjct: 283 VNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEML 342
Query: 821 LDN-GANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATE---KTALAV-AK 875
+ + A + D ++NT LH A G+ +A ++L D L+NAT +T L V A+
Sbjct: 343 VSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAAR 402
Query: 876 DKVHLTIIDLIDNYANKYA 894
+ + + + +L+ A+ A
Sbjct: 403 NGLTMVVQELLGKGASVLA 421
Score = 57.6 bits (133), Expect = 2e-07
Identities = 39/151 (25%), Positives = 73/151 (48%), Gaps = 13/151 (8%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDL---NECSALHYASSRGHQNVLLMLLHSGAN 550
T +H A+ +G + + L+ NA D+ N + L + GH + + LL+ GAN
Sbjct: 86 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 145
Query: 551 INQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYE 610
++ K+ T LH GH CV A++ +H + + + G TP+HL++ G+
Sbjct: 146 VDAKDKWGRTALHRGAVTGHEECVDALL---QHGAKCL---LRDSRGRTPIHLSAACGHI 199
Query: 611 GIARLLIEHG----SEPSLQNSYHKTAFDYA 637
G+ L++ + P+ +++ TA +A
Sbjct: 200 GVLGALLQSAASMDANPATADNHGYTALHWA 230
Score = 57.2 bits (132), Expect = 2e-07
Identities = 41/149 (27%), Positives = 74/149 (49%), Gaps = 9/149 (6%)
Query: 488 RDSHGLTALHVASIHGKATIVETLLEMGSEINAT----DLNECSALHYASSRGHQNVLLM 543
RDS G T +H+++ G ++ LL+ + ++A D + +ALH+A GH+ + +
Sbjct: 182 RDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVEL 241
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL + + +PLH AV N + + +I + G I +N + G TPLH
Sbjct: 242 LLEQEV-FQKTEGNAFSPLHCAVINDNEGAAEMLI---DTLGASI-VNATDSKGRTPLHA 296
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKT 632
A+ + +LL+ H ++ + +S KT
Sbjct: 297 AAFTDHVECLQLLLSHNAQVNSVDSTGKT 325
Score = 50.4 bits (115), Expect = 3e-05
Identities = 25/84 (29%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Query: 772 LHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAID 831
LH AA +G + +L+ + +++ RN +TPL LAA + +L++ GA+I D
Sbjct: 21 LHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKD 80
Query: 832 -VARNTPLHDASETGNIGAAKILL 854
+ + TP+H A+ G+ ++L+
Sbjct: 81 YILKRTPIHAAATNGHSECLRLLI 104
Score = 49.6 bits (113), Expect = 5e-05
Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 3/86 (3%)
Query: 755 SCTDFDVNVCDSNGFTALHYAARYGLDEFCNIL---IFNRANVNCRNKKAQTPLHLAAIN 811
S ++ + D++ TALH A G + ++ I +R +N N QTPLH+AA N
Sbjct: 344 SSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARN 403
Query: 812 NKTVVIRLLLDNGANINAIDVARNTP 837
T+V++ LL GA++ A+D TP
Sbjct: 404 GLTMVVQELLGKGASVLAVDENGYTP 429
Score = 48.4 bits (110), Expect = 1e-04
Identities = 38/130 (29%), Positives = 58/130 (44%), Gaps = 4/130 (3%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
V++ D NG T L + G + L+ ANV+ ++K +T LH A+ + L
Sbjct: 113 VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDAL 172
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEK----TALAVAKD 876
L +GA D TP+H ++ G+IG LL + AT TAL A
Sbjct: 173 LQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACY 232
Query: 877 KVHLTIIDLI 886
H T ++L+
Sbjct: 233 NGHETCVELL 242
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/137 (27%), Positives = 65/137 (47%), Gaps = 4/137 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNK-KAQTPLHLAAINNKTVVIR 818
D++V +S+G T L AA G E ++LI A++ ++ +TP+H AA N + +R
Sbjct: 42 DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLR 101
Query: 819 LLLDNGANINAIDVA---RNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAK 875
LL+ N NA+D+ TPL + G+ LL+ ++ + +TAL
Sbjct: 102 LLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGA 161
Query: 876 DKVHLTIIDLIDNYANK 892
H +D + + K
Sbjct: 162 VTGHEECVDALLQHGAK 178
Score = 41.5 bits (93), Expect = 0.013
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 4/99 (4%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+V+ D G TALH A G +E + L+ + A R+ + +TP+HL+A V+
Sbjct: 145 NVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 204
Query: 820 LLDNGANINA----IDVARNTPLHDASETGNIGAAKILL 854
LL + A+++A D T LH A G+ ++LL
Sbjct: 205 LLQSAASMDANPATADNHGYTALHWACYNGHETCVELLL 243
Score = 36.3 bits (80), Expect = 0.48
Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSE---INATDLNECSALHYASSRGHQNVL 541
+T +D+ TALH+A G T +LE ++ INAT+ + LH A+ G V+
Sbjct: 350 LTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVV 409
Query: 542 LMLLHSGANINQKNIDKNTP-LHLAVNNGHLHCVKAII 578
LL GA++ + + TP L A N C+ I+
Sbjct: 410 QELLGKGASVLAVDENGYTPALACAPNKDVADCLALIL 447
>D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein.
Length = 1180
Score = 72.1 bits (169), Expect = 8e-12
Identities = 44/151 (29%), Positives = 80/151 (52%), Gaps = 8/151 (5%)
Query: 508 VETLLEM--GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLA 565
+ +LL M G +N D + LH+A+ GH++V+ +LL + A N + PLHLA
Sbjct: 107 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA 166
Query: 566 VNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSL 625
G V+ +I+ R +N N T LH A+++G+ + ++L+E ++P++
Sbjct: 167 AWKGDAQIVRLLIHQGPSHTR---VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTM 223
Query: 626 QNSYHKTAFDYA---HNLRILQVLKSCTPNL 653
+N+ +T D A L ++++L + PNL
Sbjct: 224 RNNKFETPLDLAALYGRLEVVKMLLNAHPNL 254
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 9/138 (6%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P + DS G T LH A+++G +VE LL + N D C LH A+ +G ++
Sbjct: 117 PNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVR 176
Query: 543 MLLHSG---ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNT 599
+L+H G +N++N D T LH A GH VK ++ + N T
Sbjct: 177 LLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLL------EELTDPTMRNNKFET 230
Query: 600 PLHLASKWGYEGIARLLI 617
PL LA+ +G + ++L+
Sbjct: 231 PLDLAALYGRLEVVKMLL 248
Score = 69.7 bits (163), Expect = 4e-11
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 3/132 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN DS G+T LH+AA G + +L+ N A N + K PLHLAA ++RL
Sbjct: 118 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRL 177
Query: 820 LLDNGANINAIDVARN---TPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
L+ G + ++ N T LH A++ G+ K+LL D T+ N +T L +A
Sbjct: 178 LIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAAL 237
Query: 877 KVHLTIIDLIDN 888
L ++ ++ N
Sbjct: 238 YGRLEVVKMLLN 249
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/147 (30%), Positives = 79/147 (53%), Gaps = 7/147 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH A+ +G +V+ LLE ++ + + L A+ G V+ MLL++ N+
Sbjct: 197 TALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLS 256
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N K+TPLHLA NGH KA++ +G ++ N E G+ LH A+ +G +
Sbjct: 257 CNTKKHTPLHLAARNGH----KAVVQVLLDAG--MDSNYQTEMGSA-LHEAALFGKTDVV 309
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNL 640
++L+ G++ ++++++ TA D L
Sbjct: 310 QILLAAGTDVNIKDNHGLTALDTVREL 336
Score = 66.5 bits (155), Expect = 4e-10
Identities = 34/99 (34%), Positives = 57/99 (57%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN +++ TALH AA+YG E +L+ + RN K +TPL LAA+ + V+++L
Sbjct: 188 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 247
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPD 859
L+ N+ + + ++TPLH A+ G+ ++LL D
Sbjct: 248 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD 286
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/107 (33%), Positives = 53/107 (49%), Gaps = 1/107 (0%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L AA YG E +L+ N+ N K TPLHLAA N V+++LLD G + N
Sbjct: 230 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSN- 288
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+ LH+A+ G +ILL+ D+ + + TAL ++
Sbjct: 289 YQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRE 335
Score = 44.0 bits (99), Expect = 0.002
Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 9/117 (7%)
Query: 534 SRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCA 593
S H L+ + G N+N + TPLH A NGH V+ ++ N A
Sbjct: 102 SSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLL------RNDALTNVA 155
Query: 594 NESGNTPLHLASKWGYEGIARLLIEHG---SEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ G PLHLA+ G I RLLI G + + QN+ ++TA A +V+K
Sbjct: 156 DSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVK 212
Score = 41.9 bits (94), Expect = 0.010
Identities = 27/98 (27%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
Query: 481 TCPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV 540
T PTM R++ T L +A+++G+ +V+ LL + + + + + LH A+ GH+ V
Sbjct: 219 TDPTM--RNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAV 276
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+ +LL +G + N + + + LH A G V+ ++
Sbjct: 277 VQVLLDAGMDSNYQT-EMGSALHEAALFGKTDVVQILL 313
>BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 72.1 bits (169), Expect = 8e-12
Identities = 44/151 (29%), Positives = 80/151 (52%), Gaps = 8/151 (5%)
Query: 508 VETLLEM--GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLA 565
+ +LL M G +N D + LH+A+ GH++V+ +LL + A N + PLHLA
Sbjct: 61 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA 120
Query: 566 VNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSL 625
G V+ +I+ R +N N T LH A+++G+ + ++L+E ++P++
Sbjct: 121 AWKGDAQIVRLLIHQGPSHTR---VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTM 177
Query: 626 QNSYHKTAFDYA---HNLRILQVLKSCTPNL 653
+N+ +T D A L ++++L + PNL
Sbjct: 178 RNNKFETPLDLAALYGRLEVVKMLLNAHPNL 208
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 9/138 (6%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P + DS G T LH A+++G +VE LL + N D C LH A+ +G ++
Sbjct: 71 PNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVR 130
Query: 543 MLLHSG---ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNT 599
+L+H G +N++N D T LH A GH VK ++ + N T
Sbjct: 131 LLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLL------EELTDPTMRNNKFET 184
Query: 600 PLHLASKWGYEGIARLLI 617
PL LA+ +G + ++L+
Sbjct: 185 PLDLAALYGRLEVVKMLL 202
Score = 69.7 bits (163), Expect = 4e-11
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 3/132 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN DS G+T LH+AA G + +L+ N A N + K PLHLAA ++RL
Sbjct: 72 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRL 131
Query: 820 LLDNGANINAIDVARN---TPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
L+ G + ++ N T LH A++ G+ K+LL D T+ N +T L +A
Sbjct: 132 LIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAAL 191
Query: 877 KVHLTIIDLIDN 888
L ++ ++ N
Sbjct: 192 YGRLEVVKMLLN 203
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/147 (30%), Positives = 79/147 (53%), Gaps = 7/147 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH A+ +G +V+ LLE ++ + + L A+ G V+ MLL++ N+
Sbjct: 151 TALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLS 210
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N K+TPLHLA NGH KA++ +G ++ N E G+ LH A+ +G +
Sbjct: 211 CNTKKHTPLHLAARNGH----KAVVQVLLDAG--MDSNYQTEMGSA-LHEAALFGKTDVV 263
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNL 640
++L+ G++ ++++++ TA D L
Sbjct: 264 QILLAAGTDVNIKDNHGLTALDTVREL 290
Score = 66.5 bits (155), Expect = 4e-10
Identities = 34/99 (34%), Positives = 57/99 (57%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN +++ TALH AA+YG E +L+ + RN K +TPL LAA+ + V+++L
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPD 859
L+ N+ + + ++TPLH A+ G+ ++LL D
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD 240
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/107 (33%), Positives = 53/107 (49%), Gaps = 1/107 (0%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L AA YG E +L+ N+ N K TPLHLAA N V+++LLD G + N
Sbjct: 184 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSN- 242
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+ LH+A+ G +ILL+ D+ + + TAL ++
Sbjct: 243 YQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRE 289
Score = 44.0 bits (99), Expect = 0.002
Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 9/117 (7%)
Query: 534 SRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCA 593
S H L+ + G N+N + TPLH A NGH V+ ++ N A
Sbjct: 56 SSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLL------RNDALTNVA 109
Query: 594 NESGNTPLHLASKWGYEGIARLLIEHG---SEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ G PLHLA+ G I RLLI G + + QN+ ++TA A +V+K
Sbjct: 110 DSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVK 166
Score = 41.9 bits (94), Expect = 0.010
Identities = 27/98 (27%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
Query: 481 TCPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV 540
T PTM R++ T L +A+++G+ +V+ LL + + + + + LH A+ GH+ V
Sbjct: 173 TDPTM--RNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAV 230
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+ +LL +G + N + + + LH A G V+ ++
Sbjct: 231 VQVLLDAGMDSNYQT-EMGSALHEAALFGKTDVVQILL 267
>BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for
IMAGE:4618556) protein.
Length = 472
Score = 72.1 bits (169), Expect = 8e-12
Identities = 44/151 (29%), Positives = 80/151 (52%), Gaps = 8/151 (5%)
Query: 508 VETLLEM--GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLA 565
+ +LL M G +N D + LH+A+ GH++V+ +LL + A N + PLHLA
Sbjct: 61 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA 120
Query: 566 VNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSL 625
G V+ +I+ R +N N T LH A+++G+ + ++L+E ++P++
Sbjct: 121 AWKGDAQIVRLLIHQGPSHTR---VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTM 177
Query: 626 QNSYHKTAFDYA---HNLRILQVLKSCTPNL 653
+N+ +T D A L ++++L + PNL
Sbjct: 178 RNNKFETPLDLAALYGRLEVVKMLLNAHPNL 208
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 9/138 (6%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P + DS G T LH A+++G +VE LL + N D C LH A+ +G ++
Sbjct: 71 PNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVR 130
Query: 543 MLLHSG---ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNT 599
+L+H G +N++N D T LH A GH VK ++ + N T
Sbjct: 131 LLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLL------EELTDPTMRNNKFET 184
Query: 600 PLHLASKWGYEGIARLLI 617
PL LA+ +G + ++L+
Sbjct: 185 PLDLAALYGRLEVVKMLL 202
Score = 69.7 bits (163), Expect = 4e-11
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 3/132 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN DS G+T LH+AA G + +L+ N A N + K PLHLAA ++RL
Sbjct: 72 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRL 131
Query: 820 LLDNGANINAIDVARN---TPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
L+ G + ++ N T LH A++ G+ K+LL D T+ N +T L +A
Sbjct: 132 LIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAAL 191
Query: 877 KVHLTIIDLIDN 888
L ++ ++ N
Sbjct: 192 YGRLEVVKMLLN 203
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/147 (30%), Positives = 79/147 (53%), Gaps = 7/147 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH A+ +G +V+ LLE ++ + + L A+ G V+ MLL++ N+
Sbjct: 151 TALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLS 210
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N K+TPLHLA NGH KA++ +G ++ N E G+ LH A+ +G +
Sbjct: 211 CNTKKHTPLHLAARNGH----KAVVQVLLDAG--MDSNYQTEMGSA-LHEAALFGKTDVV 263
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNL 640
++L+ G++ ++++++ TA D L
Sbjct: 264 QILLAAGTDVNIKDNHGLTALDTVREL 290
Score = 66.5 bits (155), Expect = 4e-10
Identities = 34/99 (34%), Positives = 57/99 (57%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN +++ TALH AA+YG E +L+ + RN K +TPL LAA+ + V+++L
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPD 859
L+ N+ + + ++TPLH A+ G+ ++LL D
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD 240
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/107 (33%), Positives = 53/107 (49%), Gaps = 1/107 (0%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L AA YG E +L+ N+ N K TPLHLAA N V+++LLD G + N
Sbjct: 184 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSN- 242
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+ LH+A+ G +ILL+ D+ + + TAL ++
Sbjct: 243 YQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRE 289
Score = 44.0 bits (99), Expect = 0.002
Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 9/117 (7%)
Query: 534 SRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCA 593
S H L+ + G N+N + TPLH A NGH V+ ++ N A
Sbjct: 56 SSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLL------RNDALTNVA 109
Query: 594 NESGNTPLHLASKWGYEGIARLLIEHG---SEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ G PLHLA+ G I RLLI G + + QN+ ++TA A +V+K
Sbjct: 110 DSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVK 166
Score = 41.9 bits (94), Expect = 0.010
Identities = 27/98 (27%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
Query: 481 TCPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV 540
T PTM R++ T L +A+++G+ +V+ LL + + + + + LH A+ GH+ V
Sbjct: 173 TDPTM--RNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAV 230
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+ +LL +G + N + + + LH A G V+ ++
Sbjct: 231 VQVLLDAGMDSNYQT-EMGSALHEAALFGKTDVVQILL 267
>AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 72.1 bits (169), Expect = 8e-12
Identities = 44/151 (29%), Positives = 80/151 (52%), Gaps = 8/151 (5%)
Query: 508 VETLLEM--GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLA 565
+ +LL M G +N D + LH+A+ GH++V+ +LL + A N + PLHLA
Sbjct: 61 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA 120
Query: 566 VNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSL 625
G V+ +I+ R +N N T LH A+++G+ + ++L+E ++P++
Sbjct: 121 AWKGDAQIVRLLIHQGPSHTR---VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTM 177
Query: 626 QNSYHKTAFDYA---HNLRILQVLKSCTPNL 653
+N+ +T D A L ++++L + PNL
Sbjct: 178 RNNKFETPLDLAALYGRLEVVKMLLNAHPNL 208
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 9/138 (6%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P + DS G T LH A+++G +VE LL + N D C LH A+ +G ++
Sbjct: 71 PNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVR 130
Query: 543 MLLHSG---ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNT 599
+L+H G +N++N D T LH A GH VK ++ + N T
Sbjct: 131 LLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLL------EELTDPTMRNNKFET 184
Query: 600 PLHLASKWGYEGIARLLI 617
PL LA+ +G + ++L+
Sbjct: 185 PLDLAALYGRLEVVKMLL 202
Score = 69.7 bits (163), Expect = 4e-11
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 3/132 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN DS G+T LH+AA G + +L+ N A N + K PLHLAA ++RL
Sbjct: 72 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRL 131
Query: 820 LLDNGANINAIDVARN---TPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
L+ G + ++ N T LH A++ G+ K+LL D T+ N +T L +A
Sbjct: 132 LIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAAL 191
Query: 877 KVHLTIIDLIDN 888
L ++ ++ N
Sbjct: 192 YGRLEVVKMLLN 203
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/147 (30%), Positives = 79/147 (53%), Gaps = 7/147 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH A+ +G +V+ LLE ++ + + L A+ G V+ MLL++ N+
Sbjct: 151 TALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLS 210
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N K+TPLHLA NGH KA++ +G ++ N E G+ LH A+ +G +
Sbjct: 211 CNTKKHTPLHLAARNGH----KAVVQVLLDAG--MDSNYQTEMGSA-LHEAALFGKTDVV 263
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNL 640
++L+ G++ ++++++ TA D L
Sbjct: 264 QILLAAGTDVNIKDNHGLTALDTVREL 290
Score = 66.5 bits (155), Expect = 4e-10
Identities = 34/99 (34%), Positives = 57/99 (57%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN +++ TALH AA+YG E +L+ + RN K +TPL LAA+ + V+++L
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPD 859
L+ N+ + + ++TPLH A+ G+ ++LL D
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD 240
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/107 (33%), Positives = 53/107 (49%), Gaps = 1/107 (0%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L AA YG E +L+ N+ N K TPLHLAA N V+++LLD G + N
Sbjct: 184 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSN- 242
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+ LH+A+ G +ILL+ D+ + + TAL ++
Sbjct: 243 YQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRE 289
Score = 44.0 bits (99), Expect = 0.002
Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 9/117 (7%)
Query: 534 SRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCA 593
S H L+ + G N+N + TPLH A NGH V+ ++ N A
Sbjct: 56 SSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLL------RNDALTNVA 109
Query: 594 NESGNTPLHLASKWGYEGIARLLIEHG---SEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ G PLHLA+ G I RLLI G + + QN+ ++TA A +V+K
Sbjct: 110 DSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVK 166
Score = 41.9 bits (94), Expect = 0.010
Identities = 27/98 (27%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
Query: 481 TCPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV 540
T PTM R++ T L +A+++G+ +V+ LL + + + + + LH A+ GH+ V
Sbjct: 173 TDPTM--RNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAV 230
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+ +LL +G + N + + + LH A G V+ ++
Sbjct: 231 VQVLLDAGMDSNYQT-EMGSALHEAALFGKTDVVQILL 267
>AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 72.1 bits (169), Expect = 8e-12
Identities = 44/151 (29%), Positives = 80/151 (52%), Gaps = 8/151 (5%)
Query: 508 VETLLEM--GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLA 565
+ +LL M G +N D + LH+A+ GH++V+ +LL + A N + PLHLA
Sbjct: 61 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA 120
Query: 566 VNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSL 625
G V+ +I+ R +N N T LH A+++G+ + ++L+E ++P++
Sbjct: 121 AWKGDAQIVRLLIHQGPSHTR---VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTM 177
Query: 626 QNSYHKTAFDYA---HNLRILQVLKSCTPNL 653
+N+ +T D A L ++++L + PNL
Sbjct: 178 RNNKFETPLDLAALYGRLEVVKMLLNAHPNL 208
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 9/138 (6%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P + DS G T LH A+++G +VE LL + N D C LH A+ +G ++
Sbjct: 71 PNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVR 130
Query: 543 MLLHSG---ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNT 599
+L+H G +N++N D T LH A GH VK ++ + N T
Sbjct: 131 LLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLL------EELTDPTMRNNKFET 184
Query: 600 PLHLASKWGYEGIARLLI 617
PL LA+ +G + ++L+
Sbjct: 185 PLDLAALYGRLEVVKMLL 202
Score = 69.7 bits (163), Expect = 4e-11
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 3/132 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN DS G+T LH+AA G + +L+ N A N + K PLHLAA ++RL
Sbjct: 72 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRL 131
Query: 820 LLDNGANINAIDVARN---TPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
L+ G + ++ N T LH A++ G+ K+LL D T+ N +T L +A
Sbjct: 132 LIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAAL 191
Query: 877 KVHLTIIDLIDN 888
L ++ ++ N
Sbjct: 192 YGRLEVVKMLLN 203
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/147 (30%), Positives = 79/147 (53%), Gaps = 7/147 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH A+ +G +V+ LLE ++ + + L A+ G V+ MLL++ N+
Sbjct: 151 TALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLS 210
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N K+TPLHLA NGH KA++ +G ++ N E G+ LH A+ +G +
Sbjct: 211 CNTKKHTPLHLAARNGH----KAVVQVLLDAG--MDSNYQTEMGSA-LHEAALFGKTDVV 263
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNL 640
++L+ G++ ++++++ TA D L
Sbjct: 264 QILLAAGTDVNIKDNHGLTALDTVREL 290
Score = 66.5 bits (155), Expect = 4e-10
Identities = 34/99 (34%), Positives = 57/99 (57%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN +++ TALH AA+YG E +L+ + RN K +TPL LAA+ + V+++L
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPD 859
L+ N+ + + ++TPLH A+ G+ ++LL D
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD 240
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/107 (33%), Positives = 53/107 (49%), Gaps = 1/107 (0%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L AA YG E +L+ N+ N K TPLHLAA N V+++LLD G + N
Sbjct: 184 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSN- 242
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+ LH+A+ G +ILL+ D+ + + TAL ++
Sbjct: 243 YQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRE 289
Score = 44.0 bits (99), Expect = 0.002
Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 9/117 (7%)
Query: 534 SRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCA 593
S H L+ + G N+N + TPLH A NGH V+ ++ N A
Sbjct: 56 SSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLL------RNDALTNVA 109
Query: 594 NESGNTPLHLASKWGYEGIARLLIEHG---SEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ G PLHLA+ G I RLLI G + + QN+ ++TA A +V+K
Sbjct: 110 DSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVK 166
Score = 41.9 bits (94), Expect = 0.010
Identities = 27/98 (27%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
Query: 481 TCPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV 540
T PTM R++ T L +A+++G+ +V+ LL + + + + + LH A+ GH+ V
Sbjct: 173 TDPTM--RNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAV 230
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+ +LL +G + N + + + LH A G V+ ++
Sbjct: 231 VQVLLDAGMDSNYQT-EMGSALHEAALFGKTDVVQILL 267
>AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 72.1 bits (169), Expect = 8e-12
Identities = 44/151 (29%), Positives = 80/151 (52%), Gaps = 8/151 (5%)
Query: 508 VETLLEM--GSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLA 565
+ +LL M G +N D + LH+A+ GH++V+ +LL + A N + PLHLA
Sbjct: 61 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA 120
Query: 566 VNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSL 625
G V+ +I+ R +N N T LH A+++G+ + ++L+E ++P++
Sbjct: 121 AWKGDAQIVRLLIHQGPSHTR---VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTM 177
Query: 626 QNSYHKTAFDYA---HNLRILQVLKSCTPNL 653
+N+ +T D A L ++++L + PNL
Sbjct: 178 RNNKFETPLDLAALYGRLEVVKMLLNAHPNL 208
Score = 72.1 bits (169), Expect = 8e-12
Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 9/138 (6%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P + DS G T LH A+++G +VE LL + N D C LH A+ +G ++
Sbjct: 71 PNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVR 130
Query: 543 MLLHSG---ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNT 599
+L+H G +N++N D T LH A GH VK ++ + N T
Sbjct: 131 LLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLL------EELTDPTMRNNKFET 184
Query: 600 PLHLASKWGYEGIARLLI 617
PL LA+ +G + ++L+
Sbjct: 185 PLDLAALYGRLEVVKMLL 202
Score = 69.7 bits (163), Expect = 4e-11
Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 3/132 (2%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
+VN DS G+T LH+AA G + +L+ N A N + K PLHLAA ++RL
Sbjct: 72 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRL 131
Query: 820 LLDNGANINAIDVARN---TPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
L+ G + ++ N T LH A++ G+ K+LL D T+ N +T L +A
Sbjct: 132 LIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAAL 191
Query: 877 KVHLTIIDLIDN 888
L ++ ++ N
Sbjct: 192 YGRLEVVKMLLN 203
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/147 (30%), Positives = 79/147 (53%), Gaps = 7/147 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
TALH A+ +G +V+ LLE ++ + + L A+ G V+ MLL++ N+
Sbjct: 151 TALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLS 210
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
N K+TPLHLA NGH KA++ +G ++ N E G+ LH A+ +G +
Sbjct: 211 CNTKKHTPLHLAARNGH----KAVVQVLLDAG--MDSNYQTEMGSA-LHEAALFGKTDVV 263
Query: 614 RLLIEHGSEPSLQNSYHKTAFDYAHNL 640
++L+ G++ ++++++ TA D L
Sbjct: 264 QILLAAGTDVNIKDNHGLTALDTVREL 290
Score = 66.5 bits (155), Expect = 4e-10
Identities = 34/99 (34%), Positives = 57/99 (57%)
Query: 761 VNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLL 820
VN +++ TALH AA+YG E +L+ + RN K +TPL LAA+ + V+++L
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 821 LDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPD 859
L+ N+ + + ++TPLH A+ G+ ++LL D
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD 240
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/107 (33%), Positives = 53/107 (49%), Gaps = 1/107 (0%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T L AA YG E +L+ N+ N K TPLHLAA N V+++LLD G + N
Sbjct: 184 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSN- 242
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKD 876
+ LH+A+ G +ILL+ D+ + + TAL ++
Sbjct: 243 YQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRE 289
Score = 44.0 bits (99), Expect = 0.002
Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 9/117 (7%)
Query: 534 SRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCA 593
S H L+ + G N+N + TPLH A NGH V+ ++ N A
Sbjct: 56 SSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLL------RNDALTNVA 109
Query: 594 NESGNTPLHLASKWGYEGIARLLIEHG---SEPSLQNSYHKTAFDYAHNLRILQVLK 647
+ G PLHLA+ G I RLLI G + + QN+ ++TA A +V+K
Sbjct: 110 DSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVK 166
Score = 41.9 bits (94), Expect = 0.010
Identities = 27/98 (27%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
Query: 481 TCPTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNV 540
T PTM R++ T L +A+++G+ +V+ LL + + + + + LH A+ GH+ V
Sbjct: 173 TDPTM--RNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAV 230
Query: 541 LLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAII 578
+ +LL +G + N + + + LH A G V+ ++
Sbjct: 231 VQVLLDAGMDSNYQT-EMGSALHEAALFGKTDVVQILL 267
>AL031177-2|CAI43133.1| 185|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 185
Score = 72.1 bits (169), Expect = 8e-12
Identities = 51/154 (33%), Positives = 75/154 (48%), Gaps = 16/154 (10%)
Query: 484 TMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLM 543
T T +DS TALH A G IVE LL++G +N D A+S+ + +M
Sbjct: 34 TRTDQDSR--TALHWACSAGHTEIVEFLLQLGVPVNDKD--------DAASKNRHEIAVM 83
Query: 544 LLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHL 603
LL GAN + K+ + T +H A G+L + ++Y+ K + N + GNTPLHL
Sbjct: 84 LLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY------KASTNIQDTEGNTPLHL 137
Query: 604 ASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A A+LL+ G+ ++N KT A
Sbjct: 138 ACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 171
Score = 56.4 bits (130), Expect = 4e-07
Identities = 36/113 (31%), Positives = 55/113 (48%)
Query: 775 AARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVAR 834
AA E +L+ AN + ++ T +H AA +I +LL A+ N D
Sbjct: 72 AASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 131
Query: 835 NTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVHLTIIDLID 887
NTPLH A + + AK+L+S I + N EKT L VAK + L + +++
Sbjct: 132 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVE 184
Score = 52.0 bits (119), Expect = 9e-06
Identities = 37/120 (30%), Positives = 64/120 (53%), Gaps = 7/120 (5%)
Query: 499 ASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQKNIDK 558
A+ + I LLE G+ +A D E +A+H A+++G+ ++ +LL+ A+ N ++ +
Sbjct: 72 AASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 131
Query: 559 NTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIARLLIE 618
NTPLHLA + + K ++ G I I N+ TPL +A K G I + ++E
Sbjct: 132 NTPLHLACDEERVEEAKLLV----SQGASIYIE--NKEEKTPLQVA-KGGLGLILKRMVE 184
Score = 48.0 bits (109), Expect = 1e-04
Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
TA+H AA G + +IL++ +A+ N ++ + TPLHLA + +LL+ GA+I
Sbjct: 100 TAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYI 159
Query: 830 IDVARNTPLHDASETGNIG 848
+ TPL A G +G
Sbjct: 160 ENKEEKTPLQVAK--GGLG 176
>AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kinase
domain containing 1 protein.
Length = 765
Score = 72.1 bits (169), Expect = 8e-12
Identities = 40/118 (33%), Positives = 64/118 (54%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N D +G+ LH+AA+ G D +L+ + A V+ + ++ TPLHLAA NN V RL
Sbjct: 420 DANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARL 479
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
L+ A+ N + TPLH A+ G++ K+L S ++ +T L +A ++
Sbjct: 480 LVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVER 537
Score = 72.1 bits (169), Expect = 8e-12
Identities = 46/133 (34%), Positives = 69/133 (51%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N+ ++ G T LH AA +G +L A ++ + + +TPLHLA K I+
Sbjct: 486 DPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQH 545
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL +GA +A+D + PLH A+ G K+LL Y + L T L +A K H
Sbjct: 546 LLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGH 605
Query: 880 LTIIDLI-DNYAN 891
L II L+ +++AN
Sbjct: 606 LEIIHLLAESHAN 618
Score = 71.7 bits (168), Expect = 1e-11
Identities = 89/368 (24%), Positives = 148/368 (40%), Gaps = 22/368 (5%)
Query: 524 NECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
N+ + LH+ ++G + +LL +++ + TPL +A + ++
Sbjct: 361 NKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGAD 420
Query: 584 SGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNS-----YHKTAFDYAH 638
+ R +E G PLH A++ G +G ARLL++HG+ Q H A +
Sbjct: 421 ANR------VDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFE 474
Query: 639 NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN 698
N+ L V + PNL E T V L Q L N +T +
Sbjct: 475 NVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRN--LRTPLH 532
Query: 699 LKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTD 758
L + +RAI + +K +D S + L +Y K
Sbjct: 533 LAVERGKVRAIQHL-LKSGAVPDALDQSGY--------GPLHTAAARGKYLICKMLLRYG 583
Query: 759 FDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
+ + G+T LH AA G E ++L + AN+ TPLHLAA + + V+
Sbjct: 584 ASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVS 643
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GA+ NA + + TPLH A + + LL ++ ++ N T +A K
Sbjct: 644 ALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKG 703
Query: 879 HLTIIDLI 886
+ I+ ++
Sbjct: 704 NTAILKVL 711
Score = 71.7 bits (168), Expect = 1e-11
Identities = 45/131 (34%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A GK ++ LL+ G+ +A D + LH A++RG + MLL GA++
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLEL 588
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
TPLHLA GHL II+ S N+ TPLHLA++ G E +
Sbjct: 589 PTHQGWTPLHLAAYKGHLE----IIHLLAES--HANMGALGAVNWTPLHLAARHGEEAVV 642
Query: 614 RLLIEHGSEPS 624
L++ G++P+
Sbjct: 643 SALLQCGADPN 653
Score = 68.9 bits (161), Expect = 7e-11
Identities = 46/146 (31%), Positives = 69/146 (47%), Gaps = 6/146 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ G I+ L E + + A + LH A+ G + V+ LL GA+
Sbjct: 593 GWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADP 652
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPLHLAV ++I EH N++ N+ G TP HLA+ G
Sbjct: 653 NAAEQSGWTPLHLAVQRSTF---LSVINLLEHHA---NVHARNKVGWTPAHLAALKGNTA 706
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYA 637
I ++L+E G++ +Q+ T A
Sbjct: 707 ILKVLVEAGAQLDVQDGVSCTPLQLA 732
Score = 67.3 bits (157), Expect = 2e-10
Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 1/131 (0%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D +G+ LH AA G C +L+ A++ + TPLHLAA +I LL ++
Sbjct: 557 DQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESH 616
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK-VHLTII 883
AN+ A+ TPLH A+ G LL D + T L +A + L++I
Sbjct: 617 ANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVI 676
Query: 884 DLIDNYANKYA 894
+L++++AN +A
Sbjct: 677 NLLEHHANVHA 687
Score = 65.7 bits (153), Expect = 7e-10
Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 6/146 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T L +A+ + + LL G++ N D + + LH+A+ G +LL GA +
Sbjct: 395 GYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACV 454
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ + + TPLHLA N + + ++ R+ + N G TPLH+A+ +G+
Sbjct: 455 DAQEREGWTPLHLAAQNNFENVARLLV------SRQADPNLHEAEGKTPLHVAAYFGHVS 508
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYA 637
+ +LL G+E Q +T A
Sbjct: 509 LVKLLTSQGAELDAQQRNLRTPLHLA 534
Score = 63.3 bits (147), Expect = 4e-09
Identities = 42/134 (31%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G LH A+ GK I + LL G+ + + LH A+ +GH ++ +L S
Sbjct: 557 DQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESH 616
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA-SKW 607
AN+ TPLHLA +G V A++ + N A +SG TPLHLA +
Sbjct: 617 ANMGALGAVNWTPLHLAARHGEEAVVSALLQCG------ADPNAAEQSGWTPLHLAVQRS 670
Query: 608 GYEGIARLLIEHGS 621
+ + LL H +
Sbjct: 671 TFLSVINLLEHHAN 684
Score = 61.7 bits (143), Expect = 1e-08
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 8/132 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A+ HG+ +V LL+ G++ NA + + + LH A R ++ LL AN++
Sbjct: 628 TPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHA 687
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
+N TP HLA G+ +K ++ + ++C TPL LA + +GI
Sbjct: 688 RNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSC------TPLQLALRSRKQGIM 741
Query: 614 RLLIEHGSEPSL 625
L G EPS+
Sbjct: 742 SFL--EGKEPSV 751
Score = 61.3 bits (142), Expect = 1e-08
Identities = 34/111 (30%), Positives = 54/111 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N + +G+T LH A + L+ + ANV+ RNK TP HLAA+ T ++++
Sbjct: 651 DPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKV 710
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTA 870
L++ GA ++ D TPL A + G L P + L ++ A
Sbjct: 711 LVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGA 761
Score = 59.3 bits (137), Expect = 6e-08
Identities = 42/170 (24%), Positives = 81/170 (47%), Gaps = 9/170 (5%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+++ G T LH+A+ + + L+ ++ N + + LH A+ GH +++ +L
Sbjct: 456 AQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTS 515
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA ++ + + TPLHLAV G + ++ ++ SG + ++SG PLH A+
Sbjct: 516 QGAELDAQQRNLRTPLHLAVERGKVRAIQHLL----KSGAV--PDALDQSGYGPLHTAAA 569
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFD---YAHNLRILQVLKSCTPNL 653
G I ++L+ +G+ L T Y +L I+ +L N+
Sbjct: 570 RGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANM 619
Score = 58.4 bits (135), Expect = 1e-07
Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 6/158 (3%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T LH G V LL +++ + + L A+ ++ +LL GA+ N
Sbjct: 363 VTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADAN 422
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + D PLH A NG + ++ +H ++ G TPLHLA++ +E +
Sbjct: 423 RVDEDGWAPLHFAAQNGDDGTARLLL---DHGAC---VDAQEREGWTPLHLAAQNNFENV 476
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCT 650
ARLL+ ++P+L + KT A + ++K T
Sbjct: 477 ARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLT 514
Score = 57.2 bits (132), Expect = 2e-07
Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 6/135 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G LH A+ +G LL+ G+ ++A + + LH A+ +NV +L+
Sbjct: 425 DEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQ 484
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N + TPLH+A GH+ VK + + + ++ + TPLHLA + G
Sbjct: 485 ADPNLHEAEGKTPLHVAAYFGHVSLVKLL------TSQGAELDAQQRNLRTPLHLAVERG 538
Query: 609 YEGIARLLIEHGSEP 623
+ L++ G+ P
Sbjct: 539 KVRAIQHLLKSGAVP 553
Score = 53.6 bits (123), Expect = 3e-06
Identities = 32/106 (30%), Positives = 54/106 (50%)
Query: 769 FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
+T LH AAR+G + + L+ A+ N + TPLHLA + + + LL++ AN++
Sbjct: 627 WTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVH 686
Query: 829 AIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
A + TP H A+ GN K+L+ + + + T L +A
Sbjct: 687 ARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLA 732
Score = 36.7 bits (81), Expect = 0.37
Identities = 22/80 (27%), Positives = 42/80 (52%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ G T LH+A V LLE + ++A + + H A+ +G+ +L +L+ +G
Sbjct: 656 EQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAG 715
Query: 549 ANINQKNIDKNTPLHLAVNN 568
A ++ ++ TPL LA+ +
Sbjct: 716 AQLDVQDGVSCTPLQLALRS 735
>AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein.
Length = 765
Score = 72.1 bits (169), Expect = 8e-12
Identities = 40/118 (33%), Positives = 64/118 (54%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N D +G+ LH+AA+ G D +L+ + A V+ + ++ TPLHLAA NN V RL
Sbjct: 420 DANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARL 479
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
L+ A+ N + TPLH A+ G++ K+L S ++ +T L +A ++
Sbjct: 480 LVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVER 537
Score = 72.1 bits (169), Expect = 8e-12
Identities = 46/133 (34%), Positives = 69/133 (51%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N+ ++ G T LH AA +G +L A ++ + + +TPLHLA K I+
Sbjct: 486 DPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQH 545
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL +GA +A+D + PLH A+ G K+LL Y + L T L +A K H
Sbjct: 546 LLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGH 605
Query: 880 LTIIDLI-DNYAN 891
L II L+ +++AN
Sbjct: 606 LEIIHLLAESHAN 618
Score = 71.7 bits (168), Expect = 1e-11
Identities = 89/368 (24%), Positives = 148/368 (40%), Gaps = 22/368 (5%)
Query: 524 NECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
N+ + LH+ ++G + +LL +++ + TPL +A + ++
Sbjct: 361 NKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGAD 420
Query: 584 SGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNS-----YHKTAFDYAH 638
+ R +E G PLH A++ G +G ARLL++HG+ Q H A +
Sbjct: 421 ANR------VDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFE 474
Query: 639 NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN 698
N+ L V + PNL E T V L Q L N +T +
Sbjct: 475 NVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRN--LRTPLH 532
Query: 699 LKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTD 758
L + +RAI + +K +D S + L +Y K
Sbjct: 533 LAVERGKVRAIQHL-LKSGAVPDALDQSGY--------GPLHTAAARGKYLICKMLLRYG 583
Query: 759 FDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
+ + G+T LH AA G E ++L + AN+ TPLHLAA + + V+
Sbjct: 584 ASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVS 643
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GA+ NA + + TPLH A + + LL ++ ++ N T +A K
Sbjct: 644 ALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKG 703
Query: 879 HLTIIDLI 886
+ I+ ++
Sbjct: 704 NTAILKVL 711
Score = 71.7 bits (168), Expect = 1e-11
Identities = 45/131 (34%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A GK ++ LL+ G+ +A D + LH A++RG + MLL GA++
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLEL 588
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
TPLHLA GHL II+ S N+ TPLHLA++ G E +
Sbjct: 589 PTHQGWTPLHLAAYKGHLE----IIHLLAES--HANMGALGAVNWTPLHLAARHGEEAVV 642
Query: 614 RLLIEHGSEPS 624
L++ G++P+
Sbjct: 643 SALLQCGADPN 653
Score = 68.9 bits (161), Expect = 7e-11
Identities = 46/146 (31%), Positives = 69/146 (47%), Gaps = 6/146 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ G I+ L E + + A + LH A+ G + V+ LL GA+
Sbjct: 593 GWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADP 652
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPLHLAV ++I EH N++ N+ G TP HLA+ G
Sbjct: 653 NAAEQSGWTPLHLAVQRSTF---LSVINLLEHHA---NVHARNKVGWTPAHLAALKGNTA 706
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYA 637
I ++L+E G++ +Q+ T A
Sbjct: 707 ILKVLVEAGAQLDVQDGVSCTPLQLA 732
Score = 67.3 bits (157), Expect = 2e-10
Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 1/131 (0%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D +G+ LH AA G C +L+ A++ + TPLHLAA +I LL ++
Sbjct: 557 DQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESH 616
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK-VHLTII 883
AN+ A+ TPLH A+ G LL D + T L +A + L++I
Sbjct: 617 ANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVI 676
Query: 884 DLIDNYANKYA 894
+L++++AN +A
Sbjct: 677 NLLEHHANVHA 687
Score = 65.7 bits (153), Expect = 7e-10
Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 6/146 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T L +A+ + + LL G++ N D + + LH+A+ G +LL GA +
Sbjct: 395 GYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACV 454
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ + + TPLHLA N + + ++ R+ + N G TPLH+A+ +G+
Sbjct: 455 DAQEREGWTPLHLAAQNNFENVARLLV------SRQADPNLHEAEGKTPLHVAAYFGHVS 508
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYA 637
+ +LL G+E Q +T A
Sbjct: 509 LVKLLTSQGAELDAQQRNLRTPLHLA 534
Score = 63.3 bits (147), Expect = 4e-09
Identities = 42/134 (31%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G LH A+ GK I + LL G+ + + LH A+ +GH ++ +L S
Sbjct: 557 DQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESH 616
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA-SKW 607
AN+ TPLHLA +G V A++ + N A +SG TPLHLA +
Sbjct: 617 ANMGALGAVNWTPLHLAARHGEEAVVSALLQCG------ADPNAAEQSGWTPLHLAVQRS 670
Query: 608 GYEGIARLLIEHGS 621
+ + LL H +
Sbjct: 671 TFLSVINLLEHHAN 684
Score = 61.7 bits (143), Expect = 1e-08
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 8/132 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A+ HG+ +V LL+ G++ NA + + + LH A R ++ LL AN++
Sbjct: 628 TPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHA 687
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
+N TP HLA G+ +K ++ + ++C TPL LA + +GI
Sbjct: 688 RNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSC------TPLQLALRSRKQGIM 741
Query: 614 RLLIEHGSEPSL 625
L G EPS+
Sbjct: 742 SFL--EGKEPSV 751
Score = 61.3 bits (142), Expect = 1e-08
Identities = 34/111 (30%), Positives = 54/111 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N + +G+T LH A + L+ + ANV+ RNK TP HLAA+ T ++++
Sbjct: 651 DPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKV 710
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTA 870
L++ GA ++ D TPL A + G L P + L ++ A
Sbjct: 711 LVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGA 761
Score = 59.3 bits (137), Expect = 6e-08
Identities = 42/170 (24%), Positives = 81/170 (47%), Gaps = 9/170 (5%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+++ G T LH+A+ + + L+ ++ N + + LH A+ GH +++ +L
Sbjct: 456 AQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTS 515
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA ++ + + TPLHLAV G + ++ ++ SG + ++SG PLH A+
Sbjct: 516 QGAELDAQQRNLRTPLHLAVERGKVRAIQHLL----KSGAV--PDALDQSGYGPLHTAAA 569
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFD---YAHNLRILQVLKSCTPNL 653
G I ++L+ +G+ L T Y +L I+ +L N+
Sbjct: 570 RGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANM 619
Score = 58.4 bits (135), Expect = 1e-07
Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 6/158 (3%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T LH G V LL +++ + + L A+ ++ +LL GA+ N
Sbjct: 363 VTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADAN 422
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + D PLH A NG + ++ +H ++ G TPLHLA++ +E +
Sbjct: 423 RVDEDGWAPLHFAAQNGDDGTARLLL---DHGAC---VDAQEREGWTPLHLAAQNNFENV 476
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCT 650
ARLL+ ++P+L + KT A + ++K T
Sbjct: 477 ARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLT 514
Score = 57.2 bits (132), Expect = 2e-07
Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 6/135 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G LH A+ +G LL+ G+ ++A + + LH A+ +NV +L+
Sbjct: 425 DEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQ 484
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N + TPLH+A GH+ VK + + + ++ + TPLHLA + G
Sbjct: 485 ADPNLHEAEGKTPLHVAAYFGHVSLVKLL------TSQGAELDAQQRNLRTPLHLAVERG 538
Query: 609 YEGIARLLIEHGSEP 623
+ L++ G+ P
Sbjct: 539 KVRAIQHLLKSGAVP 553
Score = 53.6 bits (123), Expect = 3e-06
Identities = 32/106 (30%), Positives = 54/106 (50%)
Query: 769 FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
+T LH AAR+G + + L+ A+ N + TPLHLA + + + LL++ AN++
Sbjct: 627 WTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVH 686
Query: 829 AIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
A + TP H A+ GN K+L+ + + + T L +A
Sbjct: 687 ARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLA 732
Score = 36.7 bits (81), Expect = 0.37
Identities = 22/80 (27%), Positives = 42/80 (52%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ G T LH+A V LLE + ++A + + H A+ +G+ +L +L+ +G
Sbjct: 656 EQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAG 715
Query: 549 ANINQKNIDKNTPLHLAVNN 568
A ++ ++ TPL LA+ +
Sbjct: 716 AQLDVQDGVSCTPLQLALRS 735
>AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2
protein.
Length = 765
Score = 72.1 bits (169), Expect = 8e-12
Identities = 40/118 (33%), Positives = 64/118 (54%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N D +G+ LH+AA+ G D +L+ + A V+ + ++ TPLHLAA NN V RL
Sbjct: 420 DANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARL 479
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK 877
L+ A+ N + TPLH A+ G++ K+L S ++ +T L +A ++
Sbjct: 480 LVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVER 537
Score = 72.1 bits (169), Expect = 8e-12
Identities = 46/133 (34%), Positives = 69/133 (51%), Gaps = 1/133 (0%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N+ ++ G T LH AA +G +L A ++ + + +TPLHLA K I+
Sbjct: 486 DPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQH 545
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKVH 879
LL +GA +A+D + PLH A+ G K+LL Y + L T L +A K H
Sbjct: 546 LLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGH 605
Query: 880 LTIIDLI-DNYAN 891
L II L+ +++AN
Sbjct: 606 LEIIHLLAESHAN 618
Score = 71.7 bits (168), Expect = 1e-11
Identities = 89/368 (24%), Positives = 148/368 (40%), Gaps = 22/368 (5%)
Query: 524 NECSALHYASSRGHQNVLLMLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEH 583
N+ + LH+ ++G + +LL +++ + TPL +A + ++
Sbjct: 361 NKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGAD 420
Query: 584 SGRKININCANESGNTPLHLASKWGYEGIARLLIEHGSEPSLQNS-----YHKTAFDYAH 638
+ R +E G PLH A++ G +G ARLL++HG+ Q H A +
Sbjct: 421 ANR------VDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFE 474
Query: 639 NLRILQVLKSCTPNLFEYIHITSSEVKKISCESEKPTSLKLQNLTLKCSDTNDASKTIEN 698
N+ L V + PNL E T V L Q L N +T +
Sbjct: 475 NVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRN--LRTPLH 532
Query: 699 LKLIERILRAISYGDVKLACFYMNIDYSAFIAPDKEKSNSLCHPLCECQYCKRKTESCTD 758
L + +RAI + +K +D S + L +Y K
Sbjct: 533 LAVERGKVRAIQHL-LKSGAVPDALDQSGY--------GPLHTAAARGKYLICKMLLRYG 583
Query: 759 FDVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIR 818
+ + G+T LH AA G E ++L + AN+ TPLHLAA + + V+
Sbjct: 584 ASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVS 643
Query: 819 LLLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDKV 878
LL GA+ NA + + TPLH A + + LL ++ ++ N T +A K
Sbjct: 644 ALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKG 703
Query: 879 HLTIIDLI 886
+ I+ ++
Sbjct: 704 NTAILKVL 711
Score = 71.7 bits (168), Expect = 1e-11
Identities = 45/131 (34%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A GK ++ LL+ G+ +A D + LH A++RG + MLL GA++
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLEL 588
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
TPLHLA GHL II+ S N+ TPLHLA++ G E +
Sbjct: 589 PTHQGWTPLHLAAYKGHLE----IIHLLAES--HANMGALGAVNWTPLHLAARHGEEAVV 642
Query: 614 RLLIEHGSEPS 624
L++ G++P+
Sbjct: 643 SALLQCGADPN 653
Score = 68.9 bits (161), Expect = 7e-11
Identities = 46/146 (31%), Positives = 69/146 (47%), Gaps = 6/146 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T LH+A+ G I+ L E + + A + LH A+ G + V+ LL GA+
Sbjct: 593 GWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADP 652
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
N TPLHLAV ++I EH N++ N+ G TP HLA+ G
Sbjct: 653 NAAEQSGWTPLHLAVQRSTF---LSVINLLEHHA---NVHARNKVGWTPAHLAALKGNTA 706
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYA 637
I ++L+E G++ +Q+ T A
Sbjct: 707 ILKVLVEAGAQLDVQDGVSCTPLQLA 732
Score = 67.3 bits (157), Expect = 2e-10
Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 1/131 (0%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNG 824
D +G+ LH AA G C +L+ A++ + TPLHLAA +I LL ++
Sbjct: 557 DQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESH 616
Query: 825 ANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVAKDK-VHLTII 883
AN+ A+ TPLH A+ G LL D + T L +A + L++I
Sbjct: 617 ANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVI 676
Query: 884 DLIDNYANKYA 894
+L++++AN +A
Sbjct: 677 NLLEHHANVHA 687
Score = 65.7 bits (153), Expect = 7e-10
Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 6/146 (4%)
Query: 492 GLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANI 551
G T L +A+ + + LL G++ N D + + LH+A+ G +LL GA +
Sbjct: 395 GYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACV 454
Query: 552 NQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEG 611
+ + + TPLHLA N + + ++ R+ + N G TPLH+A+ +G+
Sbjct: 455 DAQEREGWTPLHLAAQNNFENVARLLV------SRQADPNLHEAEGKTPLHVAAYFGHVS 508
Query: 612 IARLLIEHGSEPSLQNSYHKTAFDYA 637
+ +LL G+E Q +T A
Sbjct: 509 LVKLLTSQGAELDAQQRNLRTPLHLA 534
Score = 63.3 bits (147), Expect = 4e-09
Identities = 42/134 (31%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G LH A+ GK I + LL G+ + + LH A+ +GH ++ +L S
Sbjct: 557 DQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESH 616
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLA-SKW 607
AN+ TPLHLA +G V A++ + N A +SG TPLHLA +
Sbjct: 617 ANMGALGAVNWTPLHLAARHGEEAVVSALLQCG------ADPNAAEQSGWTPLHLAVQRS 670
Query: 608 GYEGIARLLIEHGS 621
+ + LL H +
Sbjct: 671 TFLSVINLLEHHAN 684
Score = 61.7 bits (143), Expect = 1e-08
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 8/132 (6%)
Query: 494 TALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANINQ 553
T LH+A+ HG+ +V LL+ G++ NA + + + LH A R ++ LL AN++
Sbjct: 628 TPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHA 687
Query: 554 KNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGIA 613
+N TP HLA G+ +K ++ + ++C TPL LA + +GI
Sbjct: 688 RNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSC------TPLQLALRSRKQGIM 741
Query: 614 RLLIEHGSEPSL 625
L G EPS+
Sbjct: 742 SFL--EGKEPSV 751
Score = 61.3 bits (142), Expect = 1e-08
Identities = 34/111 (30%), Positives = 54/111 (48%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
D N + +G+T LH A + L+ + ANV+ RNK TP HLAA+ T ++++
Sbjct: 651 DPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKV 710
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTA 870
L++ GA ++ D TPL A + G L P + L ++ A
Sbjct: 711 LVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGA 761
Score = 59.3 bits (137), Expect = 6e-08
Identities = 42/170 (24%), Positives = 81/170 (47%), Gaps = 9/170 (5%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLH 546
+++ G T LH+A+ + + L+ ++ N + + LH A+ GH +++ +L
Sbjct: 456 AQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTS 515
Query: 547 SGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASK 606
GA ++ + + TPLHLAV G + ++ ++ SG + ++SG PLH A+
Sbjct: 516 QGAELDAQQRNLRTPLHLAVERGKVRAIQHLL----KSGAV--PDALDQSGYGPLHTAAA 569
Query: 607 WGYEGIARLLIEHGSEPSLQNSYHKTAFD---YAHNLRILQVLKSCTPNL 653
G I ++L+ +G+ L T Y +L I+ +L N+
Sbjct: 570 RGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANM 619
Score = 58.4 bits (135), Expect = 1e-07
Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 6/158 (3%)
Query: 493 LTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSGANIN 552
+T LH G V LL +++ + + L A+ ++ +LL GA+ N
Sbjct: 363 VTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADAN 422
Query: 553 QKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWGYEGI 612
+ + D PLH A NG + ++ +H ++ G TPLHLA++ +E +
Sbjct: 423 RVDEDGWAPLHFAAQNGDDGTARLLL---DHGAC---VDAQEREGWTPLHLAAQNNFENV 476
Query: 613 ARLLIEHGSEPSLQNSYHKTAFDYAHNLRILQVLKSCT 650
ARLL+ ++P+L + KT A + ++K T
Sbjct: 477 ARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLT 514
Score = 57.2 bits (132), Expect = 2e-07
Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 6/135 (4%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
D G LH A+ +G LL+ G+ ++A + + LH A+ +NV +L+
Sbjct: 425 DEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQ 484
Query: 549 ANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLASKWG 608
A+ N + TPLH+A GH+ VK + + + ++ + TPLHLA + G
Sbjct: 485 ADPNLHEAEGKTPLHVAAYFGHVSLVKLL------TSQGAELDAQQRNLRTPLHLAVERG 538
Query: 609 YEGIARLLIEHGSEP 623
+ L++ G+ P
Sbjct: 539 KVRAIQHLLKSGAVP 553
Score = 53.6 bits (123), Expect = 3e-06
Identities = 32/106 (30%), Positives = 54/106 (50%)
Query: 769 FTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANIN 828
+T LH AAR+G + + L+ A+ N + TPLHLA + + + LL++ AN++
Sbjct: 627 WTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVH 686
Query: 829 AIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
A + TP H A+ GN K+L+ + + + T L +A
Sbjct: 687 ARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLA 732
Score = 36.7 bits (81), Expect = 0.37
Identities = 22/80 (27%), Positives = 42/80 (52%)
Query: 489 DSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLMLLHSG 548
+ G T LH+A V LLE + ++A + + H A+ +G+ +L +L+ +G
Sbjct: 656 EQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAG 715
Query: 549 ANINQKNIDKNTPLHLAVNN 568
A ++ ++ TPL LA+ +
Sbjct: 716 AQLDVQDGVSCTPLQLALRS 735
>X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein.
Length = 1001
Score = 71.7 bits (168), Expect = 1e-11
Identities = 43/150 (28%), Positives = 74/150 (49%), Gaps = 7/150 (4%)
Query: 487 SRDSHGLTALHVASIHGKATIVETLLEMGS-EINATDLNECSALHYASSRGHQNVLLMLL 545
S++ G T LH A+ G +V LL G ++NA D + + +A+ H V+ MLL
Sbjct: 537 SKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLL 596
Query: 546 HSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLHLAS 605
GA++ + ++N LH A G + ++ + +++ N G+TPLH+A+
Sbjct: 597 TRGADVTLTDNEENICLHWASFTGSAAIAEVLL------NARCDLHAVNYHGDTPLHIAA 650
Query: 606 KWGYEGIARLLIEHGSEPSLQNSYHKTAFD 635
+ Y L + G+ P L+N TA+D
Sbjct: 651 RESYHDCVLLFLSRGANPELRNKEGDTAWD 680
Score = 64.9 bits (151), Expect = 1e-09
Identities = 41/129 (31%), Positives = 69/129 (53%), Gaps = 2/129 (1%)
Query: 765 DSNGFTALHYAARYGLDEFCNILIFN-RANVNCRNKKAQTPLHLAAINNKTVVIRLLLDN 823
+ +G T LH+AA+ G E ++L+ + +VN ++ TP+ AA + VIR+LL
Sbjct: 539 EEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTR 598
Query: 824 GANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAV-AKDKVHLTI 882
GA++ D N LH AS TG+ A++LL+ D+ +N T L + A++ H +
Sbjct: 599 GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCV 658
Query: 883 IDLIDNYAN 891
+ + AN
Sbjct: 659 LLFLSRGAN 667
Score = 64.1 bits (149), Expect = 2e-09
Identities = 36/118 (30%), Positives = 64/118 (54%), Gaps = 1/118 (0%)
Query: 770 TALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINA 829
T LH AA+ G E C++L+ AN+N +K+ +TPL A +NN V R ++ G + +
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 830 IDVARNTPLHDASETGNIGAAKILLSYNP-DITLLNATEKTALAVAKDKVHLTIIDLI 886
+ +T LH A++ GN+ +LLS D+ ++ T + A + H+ +I ++
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 595
Score = 61.7 bits (143), Expect = 1e-08
Identities = 40/155 (25%), Positives = 70/155 (45%), Gaps = 5/155 (3%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLL 542
P S T LH A+ G I LL+ G+ INA D + + L A H V
Sbjct: 467 PNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVAR 526
Query: 543 MLLHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTPLH 602
++ G + K D +T LH A G+L V ++ S ++++N + G TP+
Sbjct: 527 YMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLL-----STGQVDVNAQDSGGWTPII 581
Query: 603 LASKWGYEGIARLLIEHGSEPSLQNSYHKTAFDYA 637
A++ + + R+L+ G++ +L ++ +A
Sbjct: 582 WAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWA 616
Score = 54.0 bits (124), Expect = 2e-06
Identities = 27/90 (30%), Positives = 48/90 (53%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+ ++DS G T + A+ H ++ LL G+++ TD E LH+AS G + +L
Sbjct: 569 VNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 628
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCV 574
L++ +++ N +TPLH+A + CV
Sbjct: 629 LNARCDLHAVNYHGDTPLHIAARESYHDCV 658
Score = 48.8 bits (111), Expect = 8e-05
Identities = 30/111 (27%), Positives = 52/111 (46%)
Query: 760 DVNVCDSNGFTALHYAARYGLDEFCNILIFNRANVNCRNKKAQTPLHLAAINNKTVVIRL 819
DVN DS G+T + +AA + E +L+ A+V + + LH A+ + +
Sbjct: 568 DVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEV 627
Query: 820 LLDNGANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTA 870
LL+ +++A++ +TPLH A+ + LS + L N TA
Sbjct: 628 LLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTA 678
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 485 MTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGHQNVLLML 544
+T D+ LH AS G A I E LL +++A + + + LH A+ + + +L+
Sbjct: 602 VTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLF 661
Query: 545 LHSGANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNT 599
L GAN +N + +T L ++ ++FA RK+ + N + T
Sbjct: 662 LSRGANPELRNKEGDTAWDLTPE-------RSDVWFALQLNRKLRLGVGNRAIRT 709
Score = 44.4 bits (100), Expect = 0.002
Identities = 21/62 (33%), Positives = 33/62 (53%)
Query: 793 NVNCRNKKAQTPLHLAAINNKTVVIRLLLDNGANINAIDVARNTPLHDASETGNIGAAKI 852
N + +TPLH AA + +LL GANINA+D + TPL +A ++ A+
Sbjct: 468 NFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARY 527
Query: 853 LL 854
++
Sbjct: 528 MV 529
Score = 38.3 bits (85), Expect = 0.12
Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
Query: 816 VIRLLLDN-GANINAIDVARNTPLHDASETGNIGAAKILLSYNPDITLLNATEKTALAVA 874
VI +LLDN N + ++ TPLH A++ G++ +LL +I ++ ++T L A
Sbjct: 457 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 516
Query: 875 KDKVHLTI 882
HL +
Sbjct: 517 VVNNHLEV 524
Score = 36.7 bits (81), Expect = 0.37
Identities = 35/140 (25%), Positives = 61/140 (43%), Gaps = 8/140 (5%)
Query: 483 PTMTSRDSHGLTALHVASIHGKATIVETLLEMGSEINATDLNECSALHYASSRGH-QNVL 541
P++T + L+A+ + G+ + + L+ SE L+ + +G Q V+
Sbjct: 399 PSLTLPNGGCLSAVGLPLGPGREALEKALVIQESERRKKLRFHPRQLYLSVKQGELQKVI 458
Query: 542 LMLLHS-GANINQKNIDKNTPLHLAVNNGHLHCVKAIIYFAEHSGRKININCANESGNTP 600
LMLL + N K TPLH A G + ++ +G NIN ++ TP
Sbjct: 459 LMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLL----QAG--ANINAVDKQQRTP 512
Query: 601 LHLASKWGYEGIARLLIEHG 620
L A + +AR +++ G
Sbjct: 513 LMEAVVNNHLEVARYMVQRG 532
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.133 0.390
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,974,544
Number of Sequences: 224733
Number of extensions: 4870876
Number of successful extensions: 35804
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 943
Number of HSP's successfully gapped in prelim test: 152
Number of HSP's that attempted gapping in prelim test: 19876
Number of HSP's gapped (non-prelim): 10000
length of query: 896
length of database: 73,234,838
effective HSP length: 97
effective length of query: 799
effective length of database: 51,435,737
effective search space: 41097153863
effective search space used: 41097153863
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 70 (32.3 bits)
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